data_9KKH
# 
_entry.id   9KKH 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9KKH         pdb_00009kkh 10.2210/pdb9kkh/pdb 
WWPDB D_1300053745 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2025-01-29 
2 'Structure model' 1 1 2025-02-19 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.pdbx_database_id_DOI'    
2 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
3 2 'Structure model' '_citation.title'                   
4 2 'Structure model' '_citation_author.identifier_ORCID' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9KKH 
_pdbx_database_status.recvd_initial_deposition_date   2024-11-13 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              gkurisu@protein.osaka-u.ac.jp 
_pdbx_contact_author.name_first         Genji 
_pdbx_contact_author.name_last          Kurisu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-5354-0807 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Uenaka, M.'  1 0009-0000-4663-7582 
'Ohnishi, Y.' 2 0000-0002-1378-054X 
'Tanaka, H.'  3 0000-0003-2035-954X 
'Kurisu, G.'  4 0000-0002-5354-0807 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Acta Crystallogr.,Sect.F' 
_citation.journal_id_ASTM           ACSFEN 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2053-230X 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
;Redox-dependent hydrogen-bond network rearrangement of ferredoxin-NADP + reductase revealed by high-resolution X-ray and neutron crystallography.
;
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1107/S2053230X25000524 
_citation.pdbx_database_id_PubMed   39913263 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Uenaka, M.'  1 0009-0000-4663-7582 
primary 'Ohnishi, Y.' 2 ?                   
primary 'Ise, A.'     3 ?                   
primary 'Yu, J.'      4 0000-0002-4450-541X 
primary 'Yano, N.'    5 0000-0001-9774-6885 
primary 'Kusaka, K.'  6 0000-0002-1664-2855 
primary 'Tanaka, H.'  7 0000-0003-2035-954X 
primary 'Kurisu, G.'  8 0000-0002-5354-0807 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Ferredoxin--NADP reductase, chloroplastic' 34848.461 1   1.18.1.2 ? ? ? 
2 non-polymer syn '2-(N-MORPHOLINO)-ETHANESULFONIC ACID'      195.237   3   ?        ? ? ? 
3 non-polymer syn 'DIHYDROFLAVINE-ADENINE DINUCLEOTIDE'       787.566   1   ?        ? ? ? 
4 water       nat water                                       18.015    510 ?        ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        FNR 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;SRSKVSVAPLHLESAKEPPLNTYKPKEPFTATIVSVESLVGPKAPGETCHIVIDHGGNVPYWEGQSYGVIPPGENPKKPG
APQNVRLYSIASTRYGDNFDGRTGSLCVRRAVYYDPETGKEDPSKNGVCSNFLCNSKPGDKIQLTGPSGKIMLLPEEDPN
ATHIMIATGTGVAPFRGYLRRMFMEDVPNYRFGGLAWLFLGVANSDSLLYDEEFTSYLKQYPDNFRYDKALSREQKNRSG
GKMYVQDKIEEYSDEIFKLLDGGAHIYFCGLKGMMPGIQDTLKKVAERRGESWDQKLAQLKKNKQWHVEVY
;
_entity_poly.pdbx_seq_one_letter_code_can   
;SRSKVSVAPLHLESAKEPPLNTYKPKEPFTATIVSVESLVGPKAPGETCHIVIDHGGNVPYWEGQSYGVIPPGENPKKPG
APQNVRLYSIASTRYGDNFDGRTGSLCVRRAVYYDPETGKEDPSKNGVCSNFLCNSKPGDKIQLTGPSGKIMLLPEEDPN
ATHIMIATGTGVAPFRGYLRRMFMEDVPNYRFGGLAWLFLGVANSDSLLYDEEFTSYLKQYPDNFRYDKALSREQKNRSG
GKMYVQDKIEEYSDEIFKLLDGGAHIYFCGLKGMMPGIQDTLKKVAERRGESWDQKLAQLKKNKQWHVEVY
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '2-(N-MORPHOLINO)-ETHANESULFONIC ACID' MES 
3 'DIHYDROFLAVINE-ADENINE DINUCLEOTIDE'  FDA 
4 water                                  HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER n 
1 2   ARG n 
1 3   SER n 
1 4   LYS n 
1 5   VAL n 
1 6   SER n 
1 7   VAL n 
1 8   ALA n 
1 9   PRO n 
1 10  LEU n 
1 11  HIS n 
1 12  LEU n 
1 13  GLU n 
1 14  SER n 
1 15  ALA n 
1 16  LYS n 
1 17  GLU n 
1 18  PRO n 
1 19  PRO n 
1 20  LEU n 
1 21  ASN n 
1 22  THR n 
1 23  TYR n 
1 24  LYS n 
1 25  PRO n 
1 26  LYS n 
1 27  GLU n 
1 28  PRO n 
1 29  PHE n 
1 30  THR n 
1 31  ALA n 
1 32  THR n 
1 33  ILE n 
1 34  VAL n 
1 35  SER n 
1 36  VAL n 
1 37  GLU n 
1 38  SER n 
1 39  LEU n 
1 40  VAL n 
1 41  GLY n 
1 42  PRO n 
1 43  LYS n 
1 44  ALA n 
1 45  PRO n 
1 46  GLY n 
1 47  GLU n 
1 48  THR n 
1 49  CYS n 
1 50  HIS n 
1 51  ILE n 
1 52  VAL n 
1 53  ILE n 
1 54  ASP n 
1 55  HIS n 
1 56  GLY n 
1 57  GLY n 
1 58  ASN n 
1 59  VAL n 
1 60  PRO n 
1 61  TYR n 
1 62  TRP n 
1 63  GLU n 
1 64  GLY n 
1 65  GLN n 
1 66  SER n 
1 67  TYR n 
1 68  GLY n 
1 69  VAL n 
1 70  ILE n 
1 71  PRO n 
1 72  PRO n 
1 73  GLY n 
1 74  GLU n 
1 75  ASN n 
1 76  PRO n 
1 77  LYS n 
1 78  LYS n 
1 79  PRO n 
1 80  GLY n 
1 81  ALA n 
1 82  PRO n 
1 83  GLN n 
1 84  ASN n 
1 85  VAL n 
1 86  ARG n 
1 87  LEU n 
1 88  TYR n 
1 89  SER n 
1 90  ILE n 
1 91  ALA n 
1 92  SER n 
1 93  THR n 
1 94  ARG n 
1 95  TYR n 
1 96  GLY n 
1 97  ASP n 
1 98  ASN n 
1 99  PHE n 
1 100 ASP n 
1 101 GLY n 
1 102 ARG n 
1 103 THR n 
1 104 GLY n 
1 105 SER n 
1 106 LEU n 
1 107 CYS n 
1 108 VAL n 
1 109 ARG n 
1 110 ARG n 
1 111 ALA n 
1 112 VAL n 
1 113 TYR n 
1 114 TYR n 
1 115 ASP n 
1 116 PRO n 
1 117 GLU n 
1 118 THR n 
1 119 GLY n 
1 120 LYS n 
1 121 GLU n 
1 122 ASP n 
1 123 PRO n 
1 124 SER n 
1 125 LYS n 
1 126 ASN n 
1 127 GLY n 
1 128 VAL n 
1 129 CYS n 
1 130 SER n 
1 131 ASN n 
1 132 PHE n 
1 133 LEU n 
1 134 CYS n 
1 135 ASN n 
1 136 SER n 
1 137 LYS n 
1 138 PRO n 
1 139 GLY n 
1 140 ASP n 
1 141 LYS n 
1 142 ILE n 
1 143 GLN n 
1 144 LEU n 
1 145 THR n 
1 146 GLY n 
1 147 PRO n 
1 148 SER n 
1 149 GLY n 
1 150 LYS n 
1 151 ILE n 
1 152 MET n 
1 153 LEU n 
1 154 LEU n 
1 155 PRO n 
1 156 GLU n 
1 157 GLU n 
1 158 ASP n 
1 159 PRO n 
1 160 ASN n 
1 161 ALA n 
1 162 THR n 
1 163 HIS n 
1 164 ILE n 
1 165 MET n 
1 166 ILE n 
1 167 ALA n 
1 168 THR n 
1 169 GLY n 
1 170 THR n 
1 171 GLY n 
1 172 VAL n 
1 173 ALA n 
1 174 PRO n 
1 175 PHE n 
1 176 ARG n 
1 177 GLY n 
1 178 TYR n 
1 179 LEU n 
1 180 ARG n 
1 181 ARG n 
1 182 MET n 
1 183 PHE n 
1 184 MET n 
1 185 GLU n 
1 186 ASP n 
1 187 VAL n 
1 188 PRO n 
1 189 ASN n 
1 190 TYR n 
1 191 ARG n 
1 192 PHE n 
1 193 GLY n 
1 194 GLY n 
1 195 LEU n 
1 196 ALA n 
1 197 TRP n 
1 198 LEU n 
1 199 PHE n 
1 200 LEU n 
1 201 GLY n 
1 202 VAL n 
1 203 ALA n 
1 204 ASN n 
1 205 SER n 
1 206 ASP n 
1 207 SER n 
1 208 LEU n 
1 209 LEU n 
1 210 TYR n 
1 211 ASP n 
1 212 GLU n 
1 213 GLU n 
1 214 PHE n 
1 215 THR n 
1 216 SER n 
1 217 TYR n 
1 218 LEU n 
1 219 LYS n 
1 220 GLN n 
1 221 TYR n 
1 222 PRO n 
1 223 ASP n 
1 224 ASN n 
1 225 PHE n 
1 226 ARG n 
1 227 TYR n 
1 228 ASP n 
1 229 LYS n 
1 230 ALA n 
1 231 LEU n 
1 232 SER n 
1 233 ARG n 
1 234 GLU n 
1 235 GLN n 
1 236 LYS n 
1 237 ASN n 
1 238 ARG n 
1 239 SER n 
1 240 GLY n 
1 241 GLY n 
1 242 LYS n 
1 243 MET n 
1 244 TYR n 
1 245 VAL n 
1 246 GLN n 
1 247 ASP n 
1 248 LYS n 
1 249 ILE n 
1 250 GLU n 
1 251 GLU n 
1 252 TYR n 
1 253 SER n 
1 254 ASP n 
1 255 GLU n 
1 256 ILE n 
1 257 PHE n 
1 258 LYS n 
1 259 LEU n 
1 260 LEU n 
1 261 ASP n 
1 262 GLY n 
1 263 GLY n 
1 264 ALA n 
1 265 HIS n 
1 266 ILE n 
1 267 TYR n 
1 268 PHE n 
1 269 CYS n 
1 270 GLY n 
1 271 LEU n 
1 272 LYS n 
1 273 GLY n 
1 274 MET n 
1 275 MET n 
1 276 PRO n 
1 277 GLY n 
1 278 ILE n 
1 279 GLN n 
1 280 ASP n 
1 281 THR n 
1 282 LEU n 
1 283 LYS n 
1 284 LYS n 
1 285 VAL n 
1 286 ALA n 
1 287 GLU n 
1 288 ARG n 
1 289 ARG n 
1 290 GLY n 
1 291 GLU n 
1 292 SER n 
1 293 TRP n 
1 294 ASP n 
1 295 GLN n 
1 296 LYS n 
1 297 LEU n 
1 298 ALA n 
1 299 GLN n 
1 300 LEU n 
1 301 LYS n 
1 302 LYS n 
1 303 ASN n 
1 304 LYS n 
1 305 GLN n 
1 306 TRP n 
1 307 HIS n 
1 308 VAL n 
1 309 GLU n 
1 310 VAL n 
1 311 TYR n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   311 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 '542713, ZEAMMB73_Zm00001d034345' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Zea mays' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     4577 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                ? 'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                               ? 'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                             ? 'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                        ? 'C4 H7 N O4'        133.103 
CYS 'L-peptide linking' y CYSTEINE                               ? 'C3 H7 N O2 S'      121.158 
FDA non-polymer         . 'DIHYDROFLAVINE-ADENINE DINUCLEOTIDE'  ? 'C27 H35 N9 O15 P2' 787.566 
GLN 'L-peptide linking' y GLUTAMINE                              ? 'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                        ? 'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                                ? 'C2 H5 N O2'        75.067  
HIS 'L-peptide linking' y HISTIDINE                              ? 'C6 H10 N3 O2 1'    156.162 
HOH non-polymer         . WATER                                  ? 'H2 O'              18.015  
ILE 'L-peptide linking' y ISOLEUCINE                             ? 'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                                ? 'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                                 ? 'C6 H15 N2 O2 1'    147.195 
MES non-polymer         . '2-(N-MORPHOLINO)-ETHANESULFONIC ACID' ? 'C6 H13 N O4 S'     195.237 
MET 'L-peptide linking' y METHIONINE                             ? 'C5 H11 N O2 S'     149.211 
PHE 'L-peptide linking' y PHENYLALANINE                          ? 'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                                ? 'C5 H9 N O2'        115.130 
SER 'L-peptide linking' y SERINE                                 ? 'C3 H7 N O3'        105.093 
THR 'L-peptide linking' y THREONINE                              ? 'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                             ? 'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                               ? 'C9 H11 N O3'       181.189 
VAL 'L-peptide linking' y VALINE                                 ? 'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER 1   1007 ?    ?   ?   A . n 
A 1 2   ARG 2   1008 ?    ?   ?   A . n 
A 1 3   SER 3   1009 1009 SER SER A . n 
A 1 4   LYS 4   1010 1010 LYS LYS A . n 
A 1 5   VAL 5   1011 1011 VAL VAL A . n 
A 1 6   SER 6   1012 1012 SER SER A . n 
A 1 7   VAL 7   1013 1013 VAL VAL A . n 
A 1 8   ALA 8   1014 1014 ALA ALA A . n 
A 1 9   PRO 9   1015 1015 PRO PRO A . n 
A 1 10  LEU 10  1016 1016 LEU LEU A . n 
A 1 11  HIS 11  1017 1017 HIS HIS A . n 
A 1 12  LEU 12  1018 1018 LEU LEU A . n 
A 1 13  GLU 13  1019 1019 GLU GLU A . n 
A 1 14  SER 14  1020 1020 SER SER A . n 
A 1 15  ALA 15  1021 1021 ALA ALA A . n 
A 1 16  LYS 16  1022 1022 LYS LYS A . n 
A 1 17  GLU 17  1023 1023 GLU GLU A . n 
A 1 18  PRO 18  1024 1024 PRO PRO A . n 
A 1 19  PRO 19  1025 1025 PRO PRO A . n 
A 1 20  LEU 20  1026 1026 LEU LEU A . n 
A 1 21  ASN 21  1027 1027 ASN ASN A . n 
A 1 22  THR 22  1028 1028 THR THR A . n 
A 1 23  TYR 23  1029 1029 TYR TYR A . n 
A 1 24  LYS 24  1030 1030 LYS LYS A . n 
A 1 25  PRO 25  1031 1031 PRO PRO A . n 
A 1 26  LYS 26  1032 1032 LYS LYS A . n 
A 1 27  GLU 27  1033 1033 GLU GLU A . n 
A 1 28  PRO 28  1034 1034 PRO PRO A . n 
A 1 29  PHE 29  1035 1035 PHE PHE A . n 
A 1 30  THR 30  1036 1036 THR THR A . n 
A 1 31  ALA 31  1037 1037 ALA ALA A . n 
A 1 32  THR 32  1038 1038 THR THR A . n 
A 1 33  ILE 33  1039 1039 ILE ILE A . n 
A 1 34  VAL 34  1040 1040 VAL VAL A . n 
A 1 35  SER 35  1041 1041 SER SER A . n 
A 1 36  VAL 36  1042 1042 VAL VAL A . n 
A 1 37  GLU 37  1043 1043 GLU GLU A . n 
A 1 38  SER 38  1044 1044 SER SER A . n 
A 1 39  LEU 39  1045 1045 LEU LEU A . n 
A 1 40  VAL 40  1046 1046 VAL VAL A . n 
A 1 41  GLY 41  1047 1047 GLY GLY A . n 
A 1 42  PRO 42  1048 1048 PRO PRO A . n 
A 1 43  LYS 43  1049 1049 LYS LYS A . n 
A 1 44  ALA 44  1050 1050 ALA ALA A . n 
A 1 45  PRO 45  1051 1051 PRO PRO A . n 
A 1 46  GLY 46  1052 1052 GLY GLY A . n 
A 1 47  GLU 47  1053 1053 GLU GLU A . n 
A 1 48  THR 48  1054 1054 THR THR A . n 
A 1 49  CYS 49  1055 1055 CYS CYS A . n 
A 1 50  HIS 50  1056 1056 HIS HIS A . n 
A 1 51  ILE 51  1057 1057 ILE ILE A . n 
A 1 52  VAL 52  1058 1058 VAL VAL A . n 
A 1 53  ILE 53  1059 1059 ILE ILE A . n 
A 1 54  ASP 54  1060 1060 ASP ASP A . n 
A 1 55  HIS 55  1061 1061 HIS HIS A . n 
A 1 56  GLY 56  1062 1062 GLY GLY A . n 
A 1 57  GLY 57  1063 1063 GLY GLY A . n 
A 1 58  ASN 58  1064 1064 ASN ASN A . n 
A 1 59  VAL 59  1065 1065 VAL VAL A . n 
A 1 60  PRO 60  1066 1066 PRO PRO A . n 
A 1 61  TYR 61  1067 1067 TYR TYR A . n 
A 1 62  TRP 62  1068 1068 TRP TRP A . n 
A 1 63  GLU 63  1069 1069 GLU GLU A . n 
A 1 64  GLY 64  1070 1070 GLY GLY A . n 
A 1 65  GLN 65  1071 1071 GLN GLN A . n 
A 1 66  SER 66  1072 1072 SER SER A . n 
A 1 67  TYR 67  1073 1073 TYR TYR A . n 
A 1 68  GLY 68  1074 1074 GLY GLY A . n 
A 1 69  VAL 69  1075 1075 VAL VAL A . n 
A 1 70  ILE 70  1076 1076 ILE ILE A . n 
A 1 71  PRO 71  1077 1077 PRO PRO A . n 
A 1 72  PRO 72  1078 1078 PRO PRO A . n 
A 1 73  GLY 73  1079 1079 GLY GLY A . n 
A 1 74  GLU 74  1080 1080 GLU GLU A . n 
A 1 75  ASN 75  1081 1081 ASN ASN A . n 
A 1 76  PRO 76  1082 1082 PRO PRO A . n 
A 1 77  LYS 77  1083 1083 LYS LYS A . n 
A 1 78  LYS 78  1084 1084 LYS LYS A . n 
A 1 79  PRO 79  1085 1085 PRO PRO A . n 
A 1 80  GLY 80  1086 1086 GLY GLY A . n 
A 1 81  ALA 81  1087 1087 ALA ALA A . n 
A 1 82  PRO 82  1088 1088 PRO PRO A . n 
A 1 83  GLN 83  1089 1089 GLN GLN A . n 
A 1 84  ASN 84  1090 1090 ASN ASN A . n 
A 1 85  VAL 85  1091 1091 VAL VAL A . n 
A 1 86  ARG 86  1092 1092 ARG ARG A . n 
A 1 87  LEU 87  1093 1093 LEU LEU A . n 
A 1 88  TYR 88  1094 1094 TYR TYR A . n 
A 1 89  SER 89  1095 1095 SER SER A . n 
A 1 90  ILE 90  1096 1096 ILE ILE A . n 
A 1 91  ALA 91  1097 1097 ALA ALA A . n 
A 1 92  SER 92  1098 1098 SER SER A . n 
A 1 93  THR 93  1099 1099 THR THR A . n 
A 1 94  ARG 94  1100 1100 ARG ARG A . n 
A 1 95  TYR 95  1101 1101 TYR TYR A . n 
A 1 96  GLY 96  1102 1102 GLY GLY A . n 
A 1 97  ASP 97  1103 1103 ASP ASP A . n 
A 1 98  ASN 98  1104 1104 ASN ASN A . n 
A 1 99  PHE 99  1105 1105 PHE PHE A . n 
A 1 100 ASP 100 1106 1106 ASP ASP A . n 
A 1 101 GLY 101 1107 1107 GLY GLY A . n 
A 1 102 ARG 102 1108 1108 ARG ARG A . n 
A 1 103 THR 103 1109 1109 THR THR A . n 
A 1 104 GLY 104 1110 1110 GLY GLY A . n 
A 1 105 SER 105 1111 1111 SER SER A . n 
A 1 106 LEU 106 1112 1112 LEU LEU A . n 
A 1 107 CYS 107 1113 1113 CYS CYS A . n 
A 1 108 VAL 108 1114 1114 VAL VAL A . n 
A 1 109 ARG 109 1115 1115 ARG ARG A . n 
A 1 110 ARG 110 1116 1116 ARG ARG A . n 
A 1 111 ALA 111 1117 1117 ALA ALA A . n 
A 1 112 VAL 112 1118 1118 VAL VAL A . n 
A 1 113 TYR 113 1119 1119 TYR TYR A . n 
A 1 114 TYR 114 1120 1120 TYR TYR A . n 
A 1 115 ASP 115 1121 1121 ASP ASP A . n 
A 1 116 PRO 116 1122 1122 PRO PRO A . n 
A 1 117 GLU 117 1123 1123 GLU GLU A . n 
A 1 118 THR 118 1124 1124 THR THR A . n 
A 1 119 GLY 119 1125 1125 GLY GLY A . n 
A 1 120 LYS 120 1126 1126 LYS LYS A . n 
A 1 121 GLU 121 1127 1127 GLU GLU A . n 
A 1 122 ASP 122 1128 1128 ASP ASP A . n 
A 1 123 PRO 123 1129 1129 PRO PRO A . n 
A 1 124 SER 124 1130 1130 SER SER A . n 
A 1 125 LYS 125 1131 1131 LYS LYS A . n 
A 1 126 ASN 126 1132 1132 ASN ASN A . n 
A 1 127 GLY 127 1133 1133 GLY GLY A . n 
A 1 128 VAL 128 1134 1134 VAL VAL A . n 
A 1 129 CYS 129 1135 1135 CYS CYS A . n 
A 1 130 SER 130 1136 1136 SER SER A . n 
A 1 131 ASN 131 1137 1137 ASN ASN A . n 
A 1 132 PHE 132 1138 1138 PHE PHE A . n 
A 1 133 LEU 133 1139 1139 LEU LEU A . n 
A 1 134 CYS 134 1140 1140 CYS CYS A . n 
A 1 135 ASN 135 1141 1141 ASN ASN A . n 
A 1 136 SER 136 1142 1142 SER SER A . n 
A 1 137 LYS 137 1143 1143 LYS LYS A . n 
A 1 138 PRO 138 1144 1144 PRO PRO A . n 
A 1 139 GLY 139 1145 1145 GLY GLY A . n 
A 1 140 ASP 140 1146 1146 ASP ASP A . n 
A 1 141 LYS 141 1147 1147 LYS LYS A . n 
A 1 142 ILE 142 1148 1148 ILE ILE A . n 
A 1 143 GLN 143 1149 1149 GLN GLN A . n 
A 1 144 LEU 144 1150 1150 LEU LEU A . n 
A 1 145 THR 145 1151 1151 THR THR A . n 
A 1 146 GLY 146 1152 1152 GLY GLY A . n 
A 1 147 PRO 147 1153 1153 PRO PRO A . n 
A 1 148 SER 148 1154 1154 SER SER A . n 
A 1 149 GLY 149 1155 1155 GLY GLY A . n 
A 1 150 LYS 150 1156 1156 LYS LYS A . n 
A 1 151 ILE 151 1157 1157 ILE ILE A . n 
A 1 152 MET 152 1158 1158 MET MET A . n 
A 1 153 LEU 153 1159 1159 LEU LEU A . n 
A 1 154 LEU 154 1160 1160 LEU LEU A . n 
A 1 155 PRO 155 1161 1161 PRO PRO A . n 
A 1 156 GLU 156 1162 1162 GLU GLU A . n 
A 1 157 GLU 157 1163 1163 GLU GLU A . n 
A 1 158 ASP 158 1164 1164 ASP ASP A . n 
A 1 159 PRO 159 1165 1165 PRO PRO A . n 
A 1 160 ASN 160 1166 1166 ASN ASN A . n 
A 1 161 ALA 161 1167 1167 ALA ALA A . n 
A 1 162 THR 162 1168 1168 THR THR A . n 
A 1 163 HIS 163 1169 1169 HIS HIS A . n 
A 1 164 ILE 164 1170 1170 ILE ILE A . n 
A 1 165 MET 165 1171 1171 MET MET A . n 
A 1 166 ILE 166 1172 1172 ILE ILE A . n 
A 1 167 ALA 167 1173 1173 ALA ALA A . n 
A 1 168 THR 168 1174 1174 THR THR A . n 
A 1 169 GLY 169 1175 1175 GLY GLY A . n 
A 1 170 THR 170 1176 1176 THR THR A . n 
A 1 171 GLY 171 1177 1177 GLY GLY A . n 
A 1 172 VAL 172 1178 1178 VAL VAL A . n 
A 1 173 ALA 173 1179 1179 ALA ALA A . n 
A 1 174 PRO 174 1180 1180 PRO PRO A . n 
A 1 175 PHE 175 1181 1181 PHE PHE A . n 
A 1 176 ARG 176 1182 1182 ARG ARG A . n 
A 1 177 GLY 177 1183 1183 GLY GLY A . n 
A 1 178 TYR 178 1184 1184 TYR TYR A . n 
A 1 179 LEU 179 1185 1185 LEU LEU A . n 
A 1 180 ARG 180 1186 1186 ARG ARG A . n 
A 1 181 ARG 181 1187 1187 ARG ARG A . n 
A 1 182 MET 182 1188 1188 MET MET A . n 
A 1 183 PHE 183 1189 1189 PHE PHE A . n 
A 1 184 MET 184 1190 1190 MET MET A . n 
A 1 185 GLU 185 1191 1191 GLU GLU A . n 
A 1 186 ASP 186 1192 1192 ASP ASP A . n 
A 1 187 VAL 187 1193 1193 VAL VAL A . n 
A 1 188 PRO 188 1194 1194 PRO PRO A . n 
A 1 189 ASN 189 1195 1195 ASN ASN A . n 
A 1 190 TYR 190 1196 1196 TYR TYR A . n 
A 1 191 ARG 191 1197 1197 ARG ARG A . n 
A 1 192 PHE 192 1198 1198 PHE PHE A . n 
A 1 193 GLY 193 1199 1199 GLY GLY A . n 
A 1 194 GLY 194 1200 1200 GLY GLY A . n 
A 1 195 LEU 195 1201 1201 LEU LEU A . n 
A 1 196 ALA 196 1202 1202 ALA ALA A . n 
A 1 197 TRP 197 1203 1203 TRP TRP A . n 
A 1 198 LEU 198 1204 1204 LEU LEU A . n 
A 1 199 PHE 199 1205 1205 PHE PHE A . n 
A 1 200 LEU 200 1206 1206 LEU LEU A . n 
A 1 201 GLY 201 1207 1207 GLY GLY A . n 
A 1 202 VAL 202 1208 1208 VAL VAL A . n 
A 1 203 ALA 203 1209 1209 ALA ALA A . n 
A 1 204 ASN 204 1210 1210 ASN ASN A . n 
A 1 205 SER 205 1211 1211 SER SER A . n 
A 1 206 ASP 206 1212 1212 ASP ASP A . n 
A 1 207 SER 207 1213 1213 SER SER A . n 
A 1 208 LEU 208 1214 1214 LEU LEU A . n 
A 1 209 LEU 209 1215 1215 LEU LEU A . n 
A 1 210 TYR 210 1216 1216 TYR TYR A . n 
A 1 211 ASP 211 1217 1217 ASP ASP A . n 
A 1 212 GLU 212 1218 1218 GLU GLU A . n 
A 1 213 GLU 213 1219 1219 GLU GLU A . n 
A 1 214 PHE 214 1220 1220 PHE PHE A . n 
A 1 215 THR 215 1221 1221 THR THR A . n 
A 1 216 SER 216 1222 1222 SER SER A . n 
A 1 217 TYR 217 1223 1223 TYR TYR A . n 
A 1 218 LEU 218 1224 1224 LEU LEU A . n 
A 1 219 LYS 219 1225 1225 LYS LYS A . n 
A 1 220 GLN 220 1226 1226 GLN GLN A . n 
A 1 221 TYR 221 1227 1227 TYR TYR A . n 
A 1 222 PRO 222 1228 1228 PRO PRO A . n 
A 1 223 ASP 223 1229 1229 ASP ASP A . n 
A 1 224 ASN 224 1230 1230 ASN ASN A . n 
A 1 225 PHE 225 1231 1231 PHE PHE A . n 
A 1 226 ARG 226 1232 1232 ARG ARG A . n 
A 1 227 TYR 227 1233 1233 TYR TYR A . n 
A 1 228 ASP 228 1234 1234 ASP ASP A . n 
A 1 229 LYS 229 1235 1235 LYS LYS A . n 
A 1 230 ALA 230 1236 1236 ALA ALA A . n 
A 1 231 LEU 231 1237 1237 LEU LEU A . n 
A 1 232 SER 232 1238 1238 SER SER A . n 
A 1 233 ARG 233 1239 1239 ARG ARG A . n 
A 1 234 GLU 234 1240 1240 GLU GLU A . n 
A 1 235 GLN 235 1241 1241 GLN GLN A . n 
A 1 236 LYS 236 1242 1242 LYS LYS A . n 
A 1 237 ASN 237 1243 1243 ASN ASN A . n 
A 1 238 ARG 238 1244 1244 ARG ARG A . n 
A 1 239 SER 239 1245 1245 SER SER A . n 
A 1 240 GLY 240 1246 1246 GLY GLY A . n 
A 1 241 GLY 241 1247 1247 GLY GLY A . n 
A 1 242 LYS 242 1248 1248 LYS LYS A . n 
A 1 243 MET 243 1249 1249 MET MET A . n 
A 1 244 TYR 244 1250 1250 TYR TYR A . n 
A 1 245 VAL 245 1251 1251 VAL VAL A . n 
A 1 246 GLN 246 1252 1252 GLN GLN A . n 
A 1 247 ASP 247 1253 1253 ASP ASP A . n 
A 1 248 LYS 248 1254 1254 LYS LYS A . n 
A 1 249 ILE 249 1255 1255 ILE ILE A . n 
A 1 250 GLU 250 1256 1256 GLU GLU A . n 
A 1 251 GLU 251 1257 1257 GLU GLU A . n 
A 1 252 TYR 252 1258 1258 TYR TYR A . n 
A 1 253 SER 253 1259 1259 SER SER A . n 
A 1 254 ASP 254 1260 1260 ASP ASP A . n 
A 1 255 GLU 255 1261 1261 GLU GLU A . n 
A 1 256 ILE 256 1262 1262 ILE ILE A . n 
A 1 257 PHE 257 1263 1263 PHE PHE A . n 
A 1 258 LYS 258 1264 1264 LYS LYS A . n 
A 1 259 LEU 259 1265 1265 LEU LEU A . n 
A 1 260 LEU 260 1266 1266 LEU LEU A . n 
A 1 261 ASP 261 1267 1267 ASP ASP A . n 
A 1 262 GLY 262 1268 1268 GLY GLY A . n 
A 1 263 GLY 263 1269 1269 GLY GLY A . n 
A 1 264 ALA 264 1270 1270 ALA ALA A . n 
A 1 265 HIS 265 1271 1271 HIS HIS A . n 
A 1 266 ILE 266 1272 1272 ILE ILE A . n 
A 1 267 TYR 267 1273 1273 TYR TYR A . n 
A 1 268 PHE 268 1274 1274 PHE PHE A . n 
A 1 269 CYS 269 1275 1275 CYS CYS A . n 
A 1 270 GLY 270 1276 1276 GLY GLY A . n 
A 1 271 LEU 271 1277 1277 LEU LEU A . n 
A 1 272 LYS 272 1278 1278 LYS LYS A . n 
A 1 273 GLY 273 1279 1279 GLY GLY A . n 
A 1 274 MET 274 1280 1280 MET MET A . n 
A 1 275 MET 275 1281 1281 MET MET A . n 
A 1 276 PRO 276 1282 1282 PRO PRO A . n 
A 1 277 GLY 277 1283 1283 GLY GLY A . n 
A 1 278 ILE 278 1284 1284 ILE ILE A . n 
A 1 279 GLN 279 1285 1285 GLN GLN A . n 
A 1 280 ASP 280 1286 1286 ASP ASP A . n 
A 1 281 THR 281 1287 1287 THR THR A . n 
A 1 282 LEU 282 1288 1288 LEU LEU A . n 
A 1 283 LYS 283 1289 1289 LYS LYS A . n 
A 1 284 LYS 284 1290 1290 LYS LYS A . n 
A 1 285 VAL 285 1291 1291 VAL VAL A . n 
A 1 286 ALA 286 1292 1292 ALA ALA A . n 
A 1 287 GLU 287 1293 1293 GLU GLU A . n 
A 1 288 ARG 288 1294 1294 ARG ARG A . n 
A 1 289 ARG 289 1295 1295 ARG ARG A . n 
A 1 290 GLY 290 1296 1296 GLY GLY A . n 
A 1 291 GLU 291 1297 1297 GLU GLU A . n 
A 1 292 SER 292 1298 1298 SER SER A . n 
A 1 293 TRP 293 1299 1299 TRP TRP A . n 
A 1 294 ASP 294 1300 1300 ASP ASP A . n 
A 1 295 GLN 295 1301 1301 GLN GLN A . n 
A 1 296 LYS 296 1302 1302 LYS LYS A . n 
A 1 297 LEU 297 1303 1303 LEU LEU A . n 
A 1 298 ALA 298 1304 1304 ALA ALA A . n 
A 1 299 GLN 299 1305 1305 GLN GLN A . n 
A 1 300 LEU 300 1306 1306 LEU LEU A . n 
A 1 301 LYS 301 1307 1307 LYS LYS A . n 
A 1 302 LYS 302 1308 1308 LYS LYS A . n 
A 1 303 ASN 303 1309 1309 ASN ASN A . n 
A 1 304 LYS 304 1310 1310 LYS LYS A . n 
A 1 305 GLN 305 1311 1311 GLN GLN A . n 
A 1 306 TRP 306 1312 1312 TRP TRP A . n 
A 1 307 HIS 307 1313 1313 HIS HIS A . n 
A 1 308 VAL 308 1314 1314 VAL VAL A . n 
A 1 309 GLU 309 1315 1315 GLU GLU A . n 
A 1 310 VAL 310 1316 1316 VAL VAL A . n 
A 1 311 TYR 311 1317 1317 TYR TYR A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        FDA 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   FDA 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 MES 1   1401 1402 MES MES A . 
C 2 MES 1   1402 1502 MES MES A . 
D 3 FDA 1   1403 1508 FDA FDA A . 
E 2 MES 1   1404 1509 MES MES A . 
F 4 HOH 1   1501 576  HOH HOH A . 
F 4 HOH 2   1502 20   HOH HOH A . 
F 4 HOH 3   1503 161  HOH HOH A . 
F 4 HOH 4   1504 520  HOH HOH A . 
F 4 HOH 5   1505 283  HOH HOH A . 
F 4 HOH 6   1506 183  HOH HOH A . 
F 4 HOH 7   1507 412  HOH HOH A . 
F 4 HOH 8   1508 265  HOH HOH A . 
F 4 HOH 9   1509 49   HOH HOH A . 
F 4 HOH 10  1510 179  HOH HOH A . 
F 4 HOH 11  1511 226  HOH HOH A . 
F 4 HOH 12  1512 379  HOH HOH A . 
F 4 HOH 13  1513 96   HOH HOH A . 
F 4 HOH 14  1514 505  HOH HOH A . 
F 4 HOH 15  1515 204  HOH HOH A . 
F 4 HOH 16  1516 639  HOH HOH A . 
F 4 HOH 17  1517 269  HOH HOH A . 
F 4 HOH 18  1518 359  HOH HOH A . 
F 4 HOH 19  1519 203  HOH HOH A . 
F 4 HOH 20  1520 167  HOH HOH A . 
F 4 HOH 21  1521 148  HOH HOH A . 
F 4 HOH 22  1522 294  HOH HOH A . 
F 4 HOH 23  1523 575  HOH HOH A . 
F 4 HOH 24  1524 564  HOH HOH A . 
F 4 HOH 25  1525 587  HOH HOH A . 
F 4 HOH 26  1526 236  HOH HOH A . 
F 4 HOH 27  1527 578  HOH HOH A . 
F 4 HOH 28  1528 256  HOH HOH A . 
F 4 HOH 29  1529 326  HOH HOH A . 
F 4 HOH 30  1530 554  HOH HOH A . 
F 4 HOH 31  1531 606  HOH HOH A . 
F 4 HOH 32  1532 282  HOH HOH A . 
F 4 HOH 33  1533 623  HOH HOH A . 
F 4 HOH 34  1534 345  HOH HOH A . 
F 4 HOH 35  1535 354  HOH HOH A . 
F 4 HOH 36  1536 363  HOH HOH A . 
F 4 HOH 37  1537 137  HOH HOH A . 
F 4 HOH 38  1538 27   HOH HOH A . 
F 4 HOH 39  1539 101  HOH HOH A . 
F 4 HOH 40  1540 190  HOH HOH A . 
F 4 HOH 41  1541 346  HOH HOH A . 
F 4 HOH 42  1542 21   HOH HOH A . 
F 4 HOH 43  1543 66   HOH HOH A . 
F 4 HOH 44  1544 18   HOH HOH A . 
F 4 HOH 45  1545 139  HOH HOH A . 
F 4 HOH 46  1546 289  HOH HOH A . 
F 4 HOH 47  1547 122  HOH HOH A . 
F 4 HOH 48  1548 335  HOH HOH A . 
F 4 HOH 49  1549 645  HOH HOH A . 
F 4 HOH 50  1550 317  HOH HOH A . 
F 4 HOH 51  1551 225  HOH HOH A . 
F 4 HOH 52  1552 466  HOH HOH A . 
F 4 HOH 53  1553 243  HOH HOH A . 
F 4 HOH 54  1554 384  HOH HOH A . 
F 4 HOH 55  1555 628  HOH HOH A . 
F 4 HOH 56  1556 439  HOH HOH A . 
F 4 HOH 57  1557 61   HOH HOH A . 
F 4 HOH 58  1558 617  HOH HOH A . 
F 4 HOH 59  1559 261  HOH HOH A . 
F 4 HOH 60  1560 176  HOH HOH A . 
F 4 HOH 61  1561 140  HOH HOH A . 
F 4 HOH 62  1562 196  HOH HOH A . 
F 4 HOH 63  1563 108  HOH HOH A . 
F 4 HOH 64  1564 89   HOH HOH A . 
F 4 HOH 65  1565 44   HOH HOH A . 
F 4 HOH 66  1566 249  HOH HOH A . 
F 4 HOH 67  1567 277  HOH HOH A . 
F 4 HOH 68  1568 2    HOH HOH A . 
F 4 HOH 69  1569 67   HOH HOH A . 
F 4 HOH 70  1570 300  HOH HOH A . 
F 4 HOH 71  1571 88   HOH HOH A . 
F 4 HOH 72  1572 76   HOH HOH A . 
F 4 HOH 73  1573 33   HOH HOH A . 
F 4 HOH 74  1574 378  HOH HOH A . 
F 4 HOH 75  1575 107  HOH HOH A . 
F 4 HOH 76  1576 608  HOH HOH A . 
F 4 HOH 77  1577 29   HOH HOH A . 
F 4 HOH 78  1578 131  HOH HOH A . 
F 4 HOH 79  1579 25   HOH HOH A . 
F 4 HOH 80  1580 36   HOH HOH A . 
F 4 HOH 81  1581 23   HOH HOH A . 
F 4 HOH 82  1582 145  HOH HOH A . 
F 4 HOH 83  1583 330  HOH HOH A . 
F 4 HOH 84  1584 352  HOH HOH A . 
F 4 HOH 85  1585 146  HOH HOH A . 
F 4 HOH 86  1586 138  HOH HOH A . 
F 4 HOH 87  1587 570  HOH HOH A . 
F 4 HOH 88  1588 3    HOH HOH A . 
F 4 HOH 89  1589 206  HOH HOH A . 
F 4 HOH 90  1590 14   HOH HOH A . 
F 4 HOH 91  1591 82   HOH HOH A . 
F 4 HOH 92  1592 156  HOH HOH A . 
F 4 HOH 93  1593 119  HOH HOH A . 
F 4 HOH 94  1594 24   HOH HOH A . 
F 4 HOH 95  1595 174  HOH HOH A . 
F 4 HOH 96  1596 68   HOH HOH A . 
F 4 HOH 97  1597 211  HOH HOH A . 
F 4 HOH 98  1598 647  HOH HOH A . 
F 4 HOH 99  1599 417  HOH HOH A . 
F 4 HOH 100 1600 55   HOH HOH A . 
F 4 HOH 101 1601 47   HOH HOH A . 
F 4 HOH 102 1602 104  HOH HOH A . 
F 4 HOH 103 1603 266  HOH HOH A . 
F 4 HOH 104 1604 589  HOH HOH A . 
F 4 HOH 105 1605 332  HOH HOH A . 
F 4 HOH 106 1606 71   HOH HOH A . 
F 4 HOH 107 1607 5    HOH HOH A . 
F 4 HOH 108 1608 115  HOH HOH A . 
F 4 HOH 109 1609 35   HOH HOH A . 
F 4 HOH 110 1610 342  HOH HOH A . 
F 4 HOH 111 1611 58   HOH HOH A . 
F 4 HOH 112 1612 30   HOH HOH A . 
F 4 HOH 113 1613 609  HOH HOH A . 
F 4 HOH 114 1614 103  HOH HOH A . 
F 4 HOH 115 1615 90   HOH HOH A . 
F 4 HOH 116 1616 42   HOH HOH A . 
F 4 HOH 117 1617 19   HOH HOH A . 
F 4 HOH 118 1618 15   HOH HOH A . 
F 4 HOH 119 1619 112  HOH HOH A . 
F 4 HOH 120 1620 267  HOH HOH A . 
F 4 HOH 121 1621 69   HOH HOH A . 
F 4 HOH 122 1622 65   HOH HOH A . 
F 4 HOH 123 1623 70   HOH HOH A . 
F 4 HOH 124 1624 287  HOH HOH A . 
F 4 HOH 125 1625 233  HOH HOH A . 
F 4 HOH 126 1626 16   HOH HOH A . 
F 4 HOH 127 1627 182  HOH HOH A . 
F 4 HOH 128 1628 87   HOH HOH A . 
F 4 HOH 129 1629 7    HOH HOH A . 
F 4 HOH 130 1630 52   HOH HOH A . 
F 4 HOH 131 1631 409  HOH HOH A . 
F 4 HOH 132 1632 556  HOH HOH A . 
F 4 HOH 133 1633 48   HOH HOH A . 
F 4 HOH 134 1634 171  HOH HOH A . 
F 4 HOH 135 1635 22   HOH HOH A . 
F 4 HOH 136 1636 559  HOH HOH A . 
F 4 HOH 137 1637 492  HOH HOH A . 
F 4 HOH 138 1638 43   HOH HOH A . 
F 4 HOH 139 1639 85   HOH HOH A . 
F 4 HOH 140 1640 348  HOH HOH A . 
F 4 HOH 141 1641 34   HOH HOH A . 
F 4 HOH 142 1642 637  HOH HOH A . 
F 4 HOH 143 1643 421  HOH HOH A . 
F 4 HOH 144 1644 385  HOH HOH A . 
F 4 HOH 145 1645 4    HOH HOH A . 
F 4 HOH 146 1646 296  HOH HOH A . 
F 4 HOH 147 1647 158  HOH HOH A . 
F 4 HOH 148 1648 231  HOH HOH A . 
F 4 HOH 149 1649 392  HOH HOH A . 
F 4 HOH 150 1650 100  HOH HOH A . 
F 4 HOH 151 1651 11   HOH HOH A . 
F 4 HOH 152 1652 595  HOH HOH A . 
F 4 HOH 153 1653 188  HOH HOH A . 
F 4 HOH 154 1654 646  HOH HOH A . 
F 4 HOH 155 1655 297  HOH HOH A . 
F 4 HOH 156 1656 39   HOH HOH A . 
F 4 HOH 157 1657 12   HOH HOH A . 
F 4 HOH 158 1658 28   HOH HOH A . 
F 4 HOH 159 1659 186  HOH HOH A . 
F 4 HOH 160 1660 312  HOH HOH A . 
F 4 HOH 161 1661 200  HOH HOH A . 
F 4 HOH 162 1662 13   HOH HOH A . 
F 4 HOH 163 1663 46   HOH HOH A . 
F 4 HOH 164 1664 60   HOH HOH A . 
F 4 HOH 165 1665 135  HOH HOH A . 
F 4 HOH 166 1666 32   HOH HOH A . 
F 4 HOH 167 1667 251  HOH HOH A . 
F 4 HOH 168 1668 442  HOH HOH A . 
F 4 HOH 169 1669 64   HOH HOH A . 
F 4 HOH 170 1670 142  HOH HOH A . 
F 4 HOH 171 1671 526  HOH HOH A . 
F 4 HOH 172 1672 143  HOH HOH A . 
F 4 HOH 173 1673 588  HOH HOH A . 
F 4 HOH 174 1674 205  HOH HOH A . 
F 4 HOH 175 1675 273  HOH HOH A . 
F 4 HOH 176 1676 218  HOH HOH A . 
F 4 HOH 177 1677 8    HOH HOH A . 
F 4 HOH 178 1678 124  HOH HOH A . 
F 4 HOH 179 1679 72   HOH HOH A . 
F 4 HOH 180 1680 26   HOH HOH A . 
F 4 HOH 181 1681 106  HOH HOH A . 
F 4 HOH 182 1682 320  HOH HOH A . 
F 4 HOH 183 1683 214  HOH HOH A . 
F 4 HOH 184 1684 62   HOH HOH A . 
F 4 HOH 185 1685 577  HOH HOH A . 
F 4 HOH 186 1686 568  HOH HOH A . 
F 4 HOH 187 1687 116  HOH HOH A . 
F 4 HOH 188 1688 84   HOH HOH A . 
F 4 HOH 189 1689 59   HOH HOH A . 
F 4 HOH 190 1690 50   HOH HOH A . 
F 4 HOH 191 1691 164  HOH HOH A . 
F 4 HOH 192 1692 97   HOH HOH A . 
F 4 HOH 193 1693 250  HOH HOH A . 
F 4 HOH 194 1694 132  HOH HOH A . 
F 4 HOH 195 1695 75   HOH HOH A . 
F 4 HOH 196 1696 640  HOH HOH A . 
F 4 HOH 197 1697 563  HOH HOH A . 
F 4 HOH 198 1698 565  HOH HOH A . 
F 4 HOH 199 1699 230  HOH HOH A . 
F 4 HOH 200 1700 643  HOH HOH A . 
F 4 HOH 201 1701 223  HOH HOH A . 
F 4 HOH 202 1702 31   HOH HOH A . 
F 4 HOH 203 1703 152  HOH HOH A . 
F 4 HOH 204 1704 473  HOH HOH A . 
F 4 HOH 205 1705 197  HOH HOH A . 
F 4 HOH 206 1706 81   HOH HOH A . 
F 4 HOH 207 1707 172  HOH HOH A . 
F 4 HOH 208 1708 51   HOH HOH A . 
F 4 HOH 209 1709 78   HOH HOH A . 
F 4 HOH 210 1710 113  HOH HOH A . 
F 4 HOH 211 1711 292  HOH HOH A . 
F 4 HOH 212 1712 227  HOH HOH A . 
F 4 HOH 213 1713 424  HOH HOH A . 
F 4 HOH 214 1714 622  HOH HOH A . 
F 4 HOH 215 1715 465  HOH HOH A . 
F 4 HOH 216 1716 92   HOH HOH A . 
F 4 HOH 217 1717 1    HOH HOH A . 
F 4 HOH 218 1718 154  HOH HOH A . 
F 4 HOH 219 1719 641  HOH HOH A . 
F 4 HOH 220 1720 452  HOH HOH A . 
F 4 HOH 221 1721 191  HOH HOH A . 
F 4 HOH 222 1722 17   HOH HOH A . 
F 4 HOH 223 1723 404  HOH HOH A . 
F 4 HOH 224 1724 6    HOH HOH A . 
F 4 HOH 225 1725 91   HOH HOH A . 
F 4 HOH 226 1726 133  HOH HOH A . 
F 4 HOH 227 1727 9    HOH HOH A . 
F 4 HOH 228 1728 383  HOH HOH A . 
F 4 HOH 229 1729 423  HOH HOH A . 
F 4 HOH 230 1730 45   HOH HOH A . 
F 4 HOH 231 1731 221  HOH HOH A . 
F 4 HOH 232 1732 338  HOH HOH A . 
F 4 HOH 233 1733 187  HOH HOH A . 
F 4 HOH 234 1734 331  HOH HOH A . 
F 4 HOH 235 1735 636  HOH HOH A . 
F 4 HOH 236 1736 462  HOH HOH A . 
F 4 HOH 237 1737 144  HOH HOH A . 
F 4 HOH 238 1738 278  HOH HOH A . 
F 4 HOH 239 1739 53   HOH HOH A . 
F 4 HOH 240 1740 558  HOH HOH A . 
F 4 HOH 241 1741 532  HOH HOH A . 
F 4 HOH 242 1742 134  HOH HOH A . 
F 4 HOH 243 1743 189  HOH HOH A . 
F 4 HOH 244 1744 86   HOH HOH A . 
F 4 HOH 245 1745 80   HOH HOH A . 
F 4 HOH 246 1746 276  HOH HOH A . 
F 4 HOH 247 1747 168  HOH HOH A . 
F 4 HOH 248 1748 337  HOH HOH A . 
F 4 HOH 249 1749 313  HOH HOH A . 
F 4 HOH 250 1750 38   HOH HOH A . 
F 4 HOH 251 1751 195  HOH HOH A . 
F 4 HOH 252 1752 625  HOH HOH A . 
F 4 HOH 253 1753 173  HOH HOH A . 
F 4 HOH 254 1754 41   HOH HOH A . 
F 4 HOH 255 1755 83   HOH HOH A . 
F 4 HOH 256 1756 99   HOH HOH A . 
F 4 HOH 257 1757 98   HOH HOH A . 
F 4 HOH 258 1758 567  HOH HOH A . 
F 4 HOH 259 1759 387  HOH HOH A . 
F 4 HOH 260 1760 207  HOH HOH A . 
F 4 HOH 261 1761 429  HOH HOH A . 
F 4 HOH 262 1762 548  HOH HOH A . 
F 4 HOH 263 1763 339  HOH HOH A . 
F 4 HOH 264 1764 539  HOH HOH A . 
F 4 HOH 265 1765 254  HOH HOH A . 
F 4 HOH 266 1766 210  HOH HOH A . 
F 4 HOH 267 1767 198  HOH HOH A . 
F 4 HOH 268 1768 202  HOH HOH A . 
F 4 HOH 269 1769 474  HOH HOH A . 
F 4 HOH 270 1770 634  HOH HOH A . 
F 4 HOH 271 1771 123  HOH HOH A . 
F 4 HOH 272 1772 10   HOH HOH A . 
F 4 HOH 273 1773 162  HOH HOH A . 
F 4 HOH 274 1774 125  HOH HOH A . 
F 4 HOH 275 1775 372  HOH HOH A . 
F 4 HOH 276 1776 57   HOH HOH A . 
F 4 HOH 277 1777 611  HOH HOH A . 
F 4 HOH 278 1778 450  HOH HOH A . 
F 4 HOH 279 1779 130  HOH HOH A . 
F 4 HOH 280 1780 310  HOH HOH A . 
F 4 HOH 281 1781 149  HOH HOH A . 
F 4 HOH 282 1782 95   HOH HOH A . 
F 4 HOH 283 1783 394  HOH HOH A . 
F 4 HOH 284 1784 333  HOH HOH A . 
F 4 HOH 285 1785 252  HOH HOH A . 
F 4 HOH 286 1786 599  HOH HOH A . 
F 4 HOH 287 1787 507  HOH HOH A . 
F 4 HOH 288 1788 40   HOH HOH A . 
F 4 HOH 289 1789 120  HOH HOH A . 
F 4 HOH 290 1790 351  HOH HOH A . 
F 4 HOH 291 1791 114  HOH HOH A . 
F 4 HOH 292 1792 648  HOH HOH A . 
F 4 HOH 293 1793 460  HOH HOH A . 
F 4 HOH 294 1794 73   HOH HOH A . 
F 4 HOH 295 1795 663  HOH HOH A . 
F 4 HOH 296 1796 279  HOH HOH A . 
F 4 HOH 297 1797 481  HOH HOH A . 
F 4 HOH 298 1798 584  HOH HOH A . 
F 4 HOH 299 1799 181  HOH HOH A . 
F 4 HOH 300 1800 54   HOH HOH A . 
F 4 HOH 301 1801 366  HOH HOH A . 
F 4 HOH 302 1802 635  HOH HOH A . 
F 4 HOH 303 1803 574  HOH HOH A . 
F 4 HOH 304 1804 193  HOH HOH A . 
F 4 HOH 305 1805 355  HOH HOH A . 
F 4 HOH 306 1806 232  HOH HOH A . 
F 4 HOH 307 1807 614  HOH HOH A . 
F 4 HOH 308 1808 314  HOH HOH A . 
F 4 HOH 309 1809 175  HOH HOH A . 
F 4 HOH 310 1810 418  HOH HOH A . 
F 4 HOH 311 1811 327  HOH HOH A . 
F 4 HOH 312 1812 157  HOH HOH A . 
F 4 HOH 313 1813 153  HOH HOH A . 
F 4 HOH 314 1814 56   HOH HOH A . 
F 4 HOH 315 1815 222  HOH HOH A . 
F 4 HOH 316 1816 430  HOH HOH A . 
F 4 HOH 317 1817 627  HOH HOH A . 
F 4 HOH 318 1818 603  HOH HOH A . 
F 4 HOH 319 1819 656  HOH HOH A . 
F 4 HOH 320 1820 444  HOH HOH A . 
F 4 HOH 321 1821 471  HOH HOH A . 
F 4 HOH 322 1822 671  HOH HOH A . 
F 4 HOH 323 1823 569  HOH HOH A . 
F 4 HOH 324 1824 649  HOH HOH A . 
F 4 HOH 325 1825 105  HOH HOH A . 
F 4 HOH 326 1826 393  HOH HOH A . 
F 4 HOH 327 1827 551  HOH HOH A . 
F 4 HOH 328 1828 489  HOH HOH A . 
F 4 HOH 329 1829 560  HOH HOH A . 
F 4 HOH 330 1830 436  HOH HOH A . 
F 4 HOH 331 1831 446  HOH HOH A . 
F 4 HOH 332 1832 309  HOH HOH A . 
F 4 HOH 333 1833 403  HOH HOH A . 
F 4 HOH 334 1834 316  HOH HOH A . 
F 4 HOH 335 1835 396  HOH HOH A . 
F 4 HOH 336 1836 407  HOH HOH A . 
F 4 HOH 337 1837 583  HOH HOH A . 
F 4 HOH 338 1838 484  HOH HOH A . 
F 4 HOH 339 1839 389  HOH HOH A . 
F 4 HOH 340 1840 555  HOH HOH A . 
F 4 HOH 341 1841 268  HOH HOH A . 
F 4 HOH 342 1842 305  HOH HOH A . 
F 4 HOH 343 1843 128  HOH HOH A . 
F 4 HOH 344 1844 562  HOH HOH A . 
F 4 HOH 345 1845 414  HOH HOH A . 
F 4 HOH 346 1846 235  HOH HOH A . 
F 4 HOH 347 1847 136  HOH HOH A . 
F 4 HOH 348 1848 657  HOH HOH A . 
F 4 HOH 349 1849 660  HOH HOH A . 
F 4 HOH 350 1850 667  HOH HOH A . 
F 4 HOH 351 1851 272  HOH HOH A . 
F 4 HOH 352 1852 185  HOH HOH A . 
F 4 HOH 353 1853 654  HOH HOH A . 
F 4 HOH 354 1854 440  HOH HOH A . 
F 4 HOH 355 1855 371  HOH HOH A . 
F 4 HOH 356 1856 413  HOH HOH A . 
F 4 HOH 357 1857 655  HOH HOH A . 
F 4 HOH 358 1858 328  HOH HOH A . 
F 4 HOH 359 1859 531  HOH HOH A . 
F 4 HOH 360 1860 580  HOH HOH A . 
F 4 HOH 361 1861 573  HOH HOH A . 
F 4 HOH 362 1862 388  HOH HOH A . 
F 4 HOH 363 1863 626  HOH HOH A . 
F 4 HOH 364 1864 401  HOH HOH A . 
F 4 HOH 365 1865 308  HOH HOH A . 
F 4 HOH 366 1866 353  HOH HOH A . 
F 4 HOH 367 1867 194  HOH HOH A . 
F 4 HOH 368 1868 77   HOH HOH A . 
F 4 HOH 369 1869 447  HOH HOH A . 
F 4 HOH 370 1870 318  HOH HOH A . 
F 4 HOH 371 1871 291  HOH HOH A . 
F 4 HOH 372 1872 177  HOH HOH A . 
F 4 HOH 373 1873 126  HOH HOH A . 
F 4 HOH 374 1874 219  HOH HOH A . 
F 4 HOH 375 1875 102  HOH HOH A . 
F 4 HOH 376 1876 307  HOH HOH A . 
F 4 HOH 377 1877 290  HOH HOH A . 
F 4 HOH 378 1878 79   HOH HOH A . 
F 4 HOH 379 1879 361  HOH HOH A . 
F 4 HOH 380 1880 437  HOH HOH A . 
F 4 HOH 381 1881 664  HOH HOH A . 
F 4 HOH 382 1882 178  HOH HOH A . 
F 4 HOH 383 1883 658  HOH HOH A . 
F 4 HOH 384 1884 480  HOH HOH A . 
F 4 HOH 385 1885 155  HOH HOH A . 
F 4 HOH 386 1886 244  HOH HOH A . 
F 4 HOH 387 1887 632  HOH HOH A . 
F 4 HOH 388 1888 512  HOH HOH A . 
F 4 HOH 389 1889 365  HOH HOH A . 
F 4 HOH 390 1890 234  HOH HOH A . 
F 4 HOH 391 1891 377  HOH HOH A . 
F 4 HOH 392 1892 624  HOH HOH A . 
F 4 HOH 393 1893 602  HOH HOH A . 
F 4 HOH 394 1894 586  HOH HOH A . 
F 4 HOH 395 1895 653  HOH HOH A . 
F 4 HOH 396 1896 241  HOH HOH A . 
F 4 HOH 397 1897 274  HOH HOH A . 
F 4 HOH 398 1898 411  HOH HOH A . 
F 4 HOH 399 1899 118  HOH HOH A . 
F 4 HOH 400 1900 213  HOH HOH A . 
F 4 HOH 401 1901 642  HOH HOH A . 
F 4 HOH 402 1902 323  HOH HOH A . 
F 4 HOH 403 1903 129  HOH HOH A . 
F 4 HOH 404 1904 600  HOH HOH A . 
F 4 HOH 405 1905 597  HOH HOH A . 
F 4 HOH 406 1906 325  HOH HOH A . 
F 4 HOH 407 1907 644  HOH HOH A . 
F 4 HOH 408 1908 360  HOH HOH A . 
F 4 HOH 409 1909 441  HOH HOH A . 
F 4 HOH 410 1910 633  HOH HOH A . 
F 4 HOH 411 1911 432  HOH HOH A . 
F 4 HOH 412 1912 662  HOH HOH A . 
F 4 HOH 413 1913 445  HOH HOH A . 
F 4 HOH 414 1914 650  HOH HOH A . 
F 4 HOH 415 1915 381  HOH HOH A . 
F 4 HOH 416 1916 229  HOH HOH A . 
F 4 HOH 417 1917 478  HOH HOH A . 
F 4 HOH 418 1918 329  HOH HOH A . 
F 4 HOH 419 1919 109  HOH HOH A . 
F 4 HOH 420 1920 490  HOH HOH A . 
F 4 HOH 421 1921 616  HOH HOH A . 
F 4 HOH 422 1922 651  HOH HOH A . 
F 4 HOH 423 1923 469  HOH HOH A . 
F 4 HOH 424 1924 216  HOH HOH A . 
F 4 HOH 425 1925 479  HOH HOH A . 
F 4 HOH 426 1926 434  HOH HOH A . 
F 4 HOH 427 1927 369  HOH HOH A . 
F 4 HOH 428 1928 37   HOH HOH A . 
F 4 HOH 429 1929 199  HOH HOH A . 
F 4 HOH 430 1930 502  HOH HOH A . 
F 4 HOH 431 1931 515  HOH HOH A . 
F 4 HOH 432 1932 304  HOH HOH A . 
F 4 HOH 433 1933 121  HOH HOH A . 
F 4 HOH 434 1934 457  HOH HOH A . 
F 4 HOH 435 1935 598  HOH HOH A . 
F 4 HOH 436 1936 240  HOH HOH A . 
F 4 HOH 437 1937 669  HOH HOH A . 
F 4 HOH 438 1938 117  HOH HOH A . 
F 4 HOH 439 1939 357  HOH HOH A . 
F 4 HOH 440 1940 615  HOH HOH A . 
F 4 HOH 441 1941 631  HOH HOH A . 
F 4 HOH 442 1942 670  HOH HOH A . 
F 4 HOH 443 1943 596  HOH HOH A . 
F 4 HOH 444 1944 260  HOH HOH A . 
F 4 HOH 445 1945 618  HOH HOH A . 
F 4 HOH 446 1946 264  HOH HOH A . 
F 4 HOH 447 1947 285  HOH HOH A . 
F 4 HOH 448 1948 613  HOH HOH A . 
F 4 HOH 449 1949 159  HOH HOH A . 
F 4 HOH 450 1950 362  HOH HOH A . 
F 4 HOH 451 1951 630  HOH HOH A . 
F 4 HOH 452 1952 228  HOH HOH A . 
F 4 HOH 453 1953 151  HOH HOH A . 
F 4 HOH 454 1954 349  HOH HOH A . 
F 4 HOH 455 1955 402  HOH HOH A . 
F 4 HOH 456 1956 356  HOH HOH A . 
F 4 HOH 457 1957 612  HOH HOH A . 
F 4 HOH 458 1958 610  HOH HOH A . 
F 4 HOH 459 1959 302  HOH HOH A . 
F 4 HOH 460 1960 263  HOH HOH A . 
F 4 HOH 461 1961 518  HOH HOH A . 
F 4 HOH 462 1962 426  HOH HOH A . 
F 4 HOH 463 1963 288  HOH HOH A . 
F 4 HOH 464 1964 659  HOH HOH A . 
F 4 HOH 465 1965 672  HOH HOH A . 
F 4 HOH 466 1966 594  HOH HOH A . 
F 4 HOH 467 1967 245  HOH HOH A . 
F 4 HOH 468 1968 541  HOH HOH A . 
F 4 HOH 469 1969 391  HOH HOH A . 
F 4 HOH 470 1970 666  HOH HOH A . 
F 4 HOH 471 1971 257  HOH HOH A . 
F 4 HOH 472 1972 321  HOH HOH A . 
F 4 HOH 473 1973 386  HOH HOH A . 
F 4 HOH 474 1974 476  HOH HOH A . 
F 4 HOH 475 1975 367  HOH HOH A . 
F 4 HOH 476 1976 486  HOH HOH A . 
F 4 HOH 477 1977 259  HOH HOH A . 
F 4 HOH 478 1978 258  HOH HOH A . 
F 4 HOH 479 1979 668  HOH HOH A . 
F 4 HOH 480 1980 571  HOH HOH A . 
F 4 HOH 481 1981 170  HOH HOH A . 
F 4 HOH 482 1982 336  HOH HOH A . 
F 4 HOH 483 1983 93   HOH HOH A . 
F 4 HOH 484 1984 180  HOH HOH A . 
F 4 HOH 485 1985 238  HOH HOH A . 
F 4 HOH 486 1986 347  HOH HOH A . 
F 4 HOH 487 1987 665  HOH HOH A . 
F 4 HOH 488 1988 306  HOH HOH A . 
F 4 HOH 489 1989 315  HOH HOH A . 
F 4 HOH 490 1990 217  HOH HOH A . 
F 4 HOH 491 1991 319  HOH HOH A . 
F 4 HOH 492 1992 208  HOH HOH A . 
F 4 HOH 493 1993 620  HOH HOH A . 
F 4 HOH 494 1994 661  HOH HOH A . 
F 4 HOH 495 1995 579  HOH HOH A . 
F 4 HOH 496 1996 127  HOH HOH A . 
F 4 HOH 497 1997 163  HOH HOH A . 
F 4 HOH 498 1998 212  HOH HOH A . 
F 4 HOH 499 1999 271  HOH HOH A . 
F 4 HOH 500 2000 299  HOH HOH A . 
F 4 HOH 501 2001 311  HOH HOH A . 
F 4 HOH 502 2002 376  HOH HOH A . 
F 4 HOH 503 2003 184  HOH HOH A . 
F 4 HOH 504 2004 74   HOH HOH A . 
F 4 HOH 505 2005 374  HOH HOH A . 
F 4 HOH 506 2006 454  HOH HOH A . 
F 4 HOH 507 2007 410  HOH HOH A . 
F 4 HOH 508 2008 652  HOH HOH A . 
F 4 HOH 509 2009 601  HOH HOH A . 
F 4 HOH 510 2010 301  HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.19.2_4158 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9KKH 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     59.080 
_cell.length_a_esd                 ? 
_cell.length_b                     59.080 
_cell.length_b_esd                 ? 
_cell.length_c                     186.900 
_cell.length_c_esd                 ? 
_cell.volume                       564964.171 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9KKH 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                154 
_symmetry.space_group_name_Hall            
;P 32 2"
;
_symmetry.space_group_name_H-M             'P 32 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9KKH 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.70 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          54.44 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'BATCH MODE' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    PEG2000 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-02-14 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.90000 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SPRING-8 BEAMLINE BL44XU' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.90000 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL44XU 
_diffrn_source.pdbx_synchrotron_site       SPring-8 
# 
_reflns.B_iso_Wilson_estimate                          11.33 
_reflns.entry_id                                       9KKH 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.10 
_reflns.d_resolution_low                               44.88 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     154328 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100.0 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          9.1 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.992 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.10 
_reflns_shell.d_res_low                                     1.12 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           3.6 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             7518 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.901 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               19.22 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9KKH 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.10 
_refine.ls_d_res_low                             44.88 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     154282 
_refine.ls_number_reflns_R_free                  2010 
_refine.ls_number_reflns_R_work                  152272 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.98 
_refine.ls_percent_reflns_R_free                 1.30 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1434 
_refine.ls_R_factor_R_free                       0.1715 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1430 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      5H59 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 16.3883 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.0922 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.10 
_refine_hist.d_res_low                        44.88 
_refine_hist.number_atoms_solvent             510 
_refine_hist.number_atoms_total               3034 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2435 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         89 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0052  ? 3039 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.9522  ? 4160 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0849  ? 413  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0079  ? 564  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 11.2629 ? 539  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.10 1.13  . . 140 10701 100.00 . . . . 0.1963 . . . . . . . . . . . 0.2260 
'X-RAY DIFFRACTION' 1.13 1.16  . . 142 10802 100.00 . . . . 0.1616 . . . . . . . . . . . 0.1913 
'X-RAY DIFFRACTION' 1.16 1.19  . . 142 10734 100.00 . . . . 0.1423 . . . . . . . . . . . 0.1627 
'X-RAY DIFFRACTION' 1.19 1.23  . . 143 10828 100.00 . . . . 0.1360 . . . . . . . . . . . 0.1648 
'X-RAY DIFFRACTION' 1.23 1.27  . . 140 10685 99.97  . . . . 0.1455 . . . . . . . . . . . 0.1563 
'X-RAY DIFFRACTION' 1.27 1.33  . . 141 10790 99.99  . . . . 0.1461 . . . . . . . . . . . 0.1897 
'X-RAY DIFFRACTION' 1.33 1.39  . . 144 10811 99.99  . . . . 0.1630 . . . . . . . . . . . 0.1805 
'X-RAY DIFFRACTION' 1.39 1.46  . . 144 10826 100.00 . . . . 0.1293 . . . . . . . . . . . 0.1680 
'X-RAY DIFFRACTION' 1.46 1.55  . . 142 10871 99.99  . . . . 0.1277 . . . . . . . . . . . 0.1355 
'X-RAY DIFFRACTION' 1.55 1.67  . . 144 10820 99.98  . . . . 0.1249 . . . . . . . . . . . 0.1649 
'X-RAY DIFFRACTION' 1.67 1.84  . . 144 10955 99.98  . . . . 0.1484 . . . . . . . . . . . 0.1641 
'X-RAY DIFFRACTION' 1.84 2.10  . . 143 10944 100.00 . . . . 0.1369 . . . . . . . . . . . 0.1500 
'X-RAY DIFFRACTION' 2.10 2.65  . . 148 11048 99.99  . . . . 0.1479 . . . . . . . . . . . 0.1586 
'X-RAY DIFFRACTION' 2.65 44.88 . . 153 11457 99.86  . . . . 0.1429 . . . . . . . . . . . 0.1938 
# 
_struct.entry_id                     9KKH 
_struct.title                        
'High resolution structure of Ferredoxin-NADP+ reductase from maize root - Reduced form, low X-ray dose' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9KKH 
_struct_keywords.text            'electron transfer, Flavoprotein, OXIDOREDUCTASE' 
_struct_keywords.pdbx_keywords   OXIDOREDUCTASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 3 ? 
E N N 2 ? 
F N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    B4G043_MAIZE 
_struct_ref.pdbx_db_accession          B4G043 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;SRSKVSVAPLHLESAKEPPLNTYKPKEPFTATIVSVESLVGPKAPGETCHIVIDHGGNVPYWEGQSYGVIPPGENPKKPG
APQNVRLYSIASTRYGDNFDGRTGSLCVRRAVYYDPETGKEDPSKNGVCSNFLCNSKPGDKIQLTGPSGKIMLLPEEDPN
ATHIMIATGTGVAPFRGYLRRMFMEDVPNYRFGGLAWLFLGVANSDSLLYDEEFTSYLKQYPDNFRYDKALSREQKNRSG
GKMYVQDKIEEYSDEIFKLLDGGAHIYFCGLKGMMPGIQDTLKKVAERRGESWDQKLAQLKKNKQWHVEVY
;
_struct_ref.pdbx_align_begin           71 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9KKH 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 311 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             B4G043 
_struct_ref_seq.db_align_beg                  71 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  381 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1007 
_struct_ref_seq.pdbx_auth_seq_align_end       1317 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 1860  ? 
1 MORE         -1    ? 
1 'SSA (A^2)'  14940 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO A 9   ? SER A 14  ? PRO A 1015 SER A 1020 5 ? 6  
HELX_P HELX_P2  AA2 ASP A 122 ? ASN A 126 ? ASP A 1128 ASN A 1132 5 ? 5  
HELX_P HELX_P3  AA3 GLY A 127 ? ASN A 135 ? GLY A 1133 ASN A 1141 1 ? 9  
HELX_P HELX_P4  AA4 VAL A 172 ? MET A 184 ? VAL A 1178 MET A 1190 1 ? 13 
HELX_P HELX_P5  AA5 ASN A 204 ? LEU A 208 ? ASN A 1210 LEU A 1214 5 ? 5  
HELX_P HELX_P6  AA6 TYR A 210 ? TYR A 221 ? TYR A 1216 TYR A 1227 1 ? 12 
HELX_P HELX_P7  AA7 TYR A 244 ? TYR A 252 ? TYR A 1250 TYR A 1258 1 ? 9  
HELX_P HELX_P8  AA8 TYR A 252 ? GLY A 262 ? TYR A 1258 GLY A 1268 1 ? 11 
HELX_P HELX_P9  AA9 MET A 274 ? ARG A 289 ? MET A 1280 ARG A 1295 1 ? 16 
HELX_P HELX_P10 AB1 SER A 292 ? ASN A 303 ? SER A 1298 ASN A 1309 1 ? 12 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            disulf1 
_struct_conn.conn_type_id                  disulf 
_struct_conn.pdbx_leaving_atom_flag        ? 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           A 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            49 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       B 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           A 
_struct_conn.ptnr2_label_comp_id           CYS 
_struct_conn.ptnr2_label_seq_id            134 
_struct_conn.ptnr2_label_atom_id           SG 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            A 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             1055 
_struct_conn.ptnr2_auth_asym_id            A 
_struct_conn.ptnr2_auth_comp_id            CYS 
_struct_conn.ptnr2_auth_seq_id             1140 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               2.127 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      CYS 
_pdbx_modification_feature.label_asym_id                      A 
_pdbx_modification_feature.label_seq_id                       49 
_pdbx_modification_feature.label_alt_id                       B 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     A 
_pdbx_modification_feature.modified_residue_label_seq_id      134 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       CYS 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        1055 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      A 
_pdbx_modification_feature.modified_residue_auth_seq_id       1140 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               SG 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                . 
_pdbx_modification_feature.ref_pcm_id                         . 
_pdbx_modification_feature.ref_comp_id                        . 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ALA 8   A . ? ALA 1014 A PRO 9   A ? PRO 1015 A 1 -3.45 
2 GLY 146 A . ? GLY 1152 A PRO 147 A ? PRO 1153 A 1 -1.95 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 6 ? 
AA3 ? 2 ? 
AA4 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? parallel      
AA4 3 4 ? parallel      
AA4 4 5 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 5   ? SER A 6   ? VAL A 1011 SER A 1012 
AA1 2 GLU A 185 ? ASP A 186 ? GLU A 1191 ASP A 1192 
AA2 1 ARG A 86  ? SER A 89  ? ARG A 1092 SER A 1095 
AA2 2 SER A 66  ? ILE A 70  ? SER A 1072 ILE A 1076 
AA2 3 LYS A 141 ? SER A 148 ? LYS A 1147 SER A 1154 
AA2 4 PHE A 29  ? SER A 38  ? PHE A 1035 SER A 1044 
AA2 5 THR A 48  ? ASP A 54  ? THR A 1054 ASP A 1060 
AA2 6 THR A 103 ? ARG A 109 ? THR A 1109 ARG A 1115 
AA3 1 GLU A 74  ? ASN A 75  ? GLU A 1080 ASN A 1081 
AA3 2 LYS A 78  ? PRO A 82  ? LYS A 1084 PRO A 1088 
AA4 1 PHE A 225 ? LEU A 231 ? PHE A 1231 LEU A 1237 
AA4 2 LEU A 195 ? VAL A 202 ? LEU A 1201 VAL A 1208 
AA4 3 THR A 162 ? THR A 168 ? THR A 1168 THR A 1174 
AA4 4 HIS A 265 ? LEU A 271 ? HIS A 1271 LEU A 1277 
AA4 5 TRP A 306 ? TYR A 311 ? TRP A 1312 TYR A 1317 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 5   ? N VAL A 1011 O ASP A 186 ? O ASP A 1192 
AA2 1 2 O TYR A 88  ? O TYR A 1094 N TYR A 67  ? N TYR A 1073 
AA2 2 3 N GLY A 68  ? N GLY A 1074 O THR A 145 ? O THR A 1151 
AA2 3 4 O LEU A 144 ? O LEU A 1150 N PHE A 29  ? N PHE A 1035 
AA2 4 5 N THR A 32  ? N THR A 1038 O ASP A 54  ? O ASP A 1060 
AA2 5 6 N ILE A 53  ? N ILE A 1059 O GLY A 104 ? O GLY A 1110 
AA3 1 2 N ASN A 75  ? N ASN A 1081 O ALA A 81  ? O ALA A 1087 
AA4 1 2 O ARG A 226 ? O ARG A 1232 N LEU A 198 ? N LEU A 1204 
AA4 2 3 O PHE A 199 ? O PHE A 1205 N MET A 165 ? N MET A 1171 
AA4 3 4 N ILE A 164 ? N ILE A 1170 O HIS A 265 ? O HIS A 1271 
AA4 4 5 N PHE A 268 ? N PHE A 1274 O GLU A 309 ? O GLU A 1315 
# 
_pdbx_entry_details.entry_id                   9KKH 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 NZ A LYS 1242 ? A O A HOH 1501 ? ? 2.10 
2 1 O  A HOH 1613 ? ? O A HOH 1740 ? ? 2.19 
# 
loop_
_pdbx_validate_symm_contact.id 
_pdbx_validate_symm_contact.PDB_model_num 
_pdbx_validate_symm_contact.auth_atom_id_1 
_pdbx_validate_symm_contact.auth_asym_id_1 
_pdbx_validate_symm_contact.auth_comp_id_1 
_pdbx_validate_symm_contact.auth_seq_id_1 
_pdbx_validate_symm_contact.PDB_ins_code_1 
_pdbx_validate_symm_contact.label_alt_id_1 
_pdbx_validate_symm_contact.site_symmetry_1 
_pdbx_validate_symm_contact.auth_atom_id_2 
_pdbx_validate_symm_contact.auth_asym_id_2 
_pdbx_validate_symm_contact.auth_comp_id_2 
_pdbx_validate_symm_contact.auth_seq_id_2 
_pdbx_validate_symm_contact.PDB_ins_code_2 
_pdbx_validate_symm_contact.label_alt_id_2 
_pdbx_validate_symm_contact.site_symmetry_2 
_pdbx_validate_symm_contact.dist 
1 1 OD2 A ASP 1128 ? A 1_555 NZ A LYS 1147 ? ? 5_445 2.15 
2 1 O1S A MES 1402 ? ? 1_555 O  A HOH 1653 ? ? 4_655 2.16 
# 
_pdbx_validate_torsion.id              1 
_pdbx_validate_torsion.PDB_model_num   1 
_pdbx_validate_torsion.auth_comp_id    GLU 
_pdbx_validate_torsion.auth_asym_id    A 
_pdbx_validate_torsion.auth_seq_id     1123 
_pdbx_validate_torsion.PDB_ins_code    ? 
_pdbx_validate_torsion.label_alt_id    B 
_pdbx_validate_torsion.phi             -91.68 
_pdbx_validate_torsion.psi             -70.04 
# 
_pdbx_struct_special_symmetry.id              1 
_pdbx_struct_special_symmetry.PDB_model_num   1 
_pdbx_struct_special_symmetry.auth_asym_id    A 
_pdbx_struct_special_symmetry.auth_comp_id    GLY 
_pdbx_struct_special_symmetry.auth_seq_id     1246 
_pdbx_struct_special_symmetry.PDB_ins_code    ? 
_pdbx_struct_special_symmetry.label_asym_id   A 
_pdbx_struct_special_symmetry.label_comp_id   GLY 
_pdbx_struct_special_symmetry.label_seq_id    240 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z          
2 -y,x-y,z+2/3   
3 -x+y,-x,z+1/3  
4 x-y,-y,-z+1/3  
5 -x,-x+y,-z+2/3 
6 y,x,-z         
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? A HOH 2008 ? 5.85 . 
2 1 O ? A HOH 2009 ? 5.90 . 
3 1 O ? A HOH 2010 ? 6.09 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A SER 1007 ? A SER 1 
2 1 Y 1 A ARG 1008 ? A ARG 2 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N N N 1   
ALA CA     C N S 2   
ALA C      C N N 3   
ALA O      O N N 4   
ALA CB     C N N 5   
ALA OXT    O N N 6   
ALA H      H N N 7   
ALA H2     H N N 8   
ALA HA     H N N 9   
ALA HB1    H N N 10  
ALA HB2    H N N 11  
ALA HB3    H N N 12  
ALA HXT    H N N 13  
ARG N      N N N 14  
ARG CA     C N S 15  
ARG C      C N N 16  
ARG O      O N N 17  
ARG CB     C N N 18  
ARG CG     C N N 19  
ARG CD     C N N 20  
ARG NE     N N N 21  
ARG CZ     C N N 22  
ARG NH1    N N N 23  
ARG NH2    N N N 24  
ARG OXT    O N N 25  
ARG H      H N N 26  
ARG H2     H N N 27  
ARG HA     H N N 28  
ARG HB2    H N N 29  
ARG HB3    H N N 30  
ARG HG2    H N N 31  
ARG HG3    H N N 32  
ARG HD2    H N N 33  
ARG HD3    H N N 34  
ARG HE     H N N 35  
ARG HH11   H N N 36  
ARG HH12   H N N 37  
ARG HH21   H N N 38  
ARG HH22   H N N 39  
ARG HXT    H N N 40  
ASN N      N N N 41  
ASN CA     C N S 42  
ASN C      C N N 43  
ASN O      O N N 44  
ASN CB     C N N 45  
ASN CG     C N N 46  
ASN OD1    O N N 47  
ASN ND2    N N N 48  
ASN OXT    O N N 49  
ASN H      H N N 50  
ASN H2     H N N 51  
ASN HA     H N N 52  
ASN HB2    H N N 53  
ASN HB3    H N N 54  
ASN HD21   H N N 55  
ASN HD22   H N N 56  
ASN HXT    H N N 57  
ASP N      N N N 58  
ASP CA     C N S 59  
ASP C      C N N 60  
ASP O      O N N 61  
ASP CB     C N N 62  
ASP CG     C N N 63  
ASP OD1    O N N 64  
ASP OD2    O N N 65  
ASP OXT    O N N 66  
ASP H      H N N 67  
ASP H2     H N N 68  
ASP HA     H N N 69  
ASP HB2    H N N 70  
ASP HB3    H N N 71  
ASP HD2    H N N 72  
ASP HXT    H N N 73  
CYS N      N N N 74  
CYS CA     C N R 75  
CYS C      C N N 76  
CYS O      O N N 77  
CYS CB     C N N 78  
CYS SG     S N N 79  
CYS OXT    O N N 80  
CYS H      H N N 81  
CYS H2     H N N 82  
CYS HA     H N N 83  
CYS HB2    H N N 84  
CYS HB3    H N N 85  
CYS HG     H N N 86  
CYS HXT    H N N 87  
FDA PA     P N S 88  
FDA O1A    O N N 89  
FDA O2A    O N N 90  
FDA O5B    O N N 91  
FDA C5B    C N N 92  
FDA C4B    C N R 93  
FDA O4B    O N N 94  
FDA C3B    C N S 95  
FDA O3B    O N N 96  
FDA C2B    C N R 97  
FDA O2B    O N N 98  
FDA C1B    C N R 99  
FDA N9A    N Y N 100 
FDA C8A    C Y N 101 
FDA N7A    N Y N 102 
FDA C5A    C Y N 103 
FDA C6A    C Y N 104 
FDA N6A    N N N 105 
FDA N1A    N Y N 106 
FDA C2A    C Y N 107 
FDA N3A    N Y N 108 
FDA C4A    C Y N 109 
FDA N1     N N N 110 
FDA C2     C N N 111 
FDA O2     O N N 112 
FDA N3     N N N 113 
FDA C4     C N N 114 
FDA O4     O N N 115 
FDA C4X    C N N 116 
FDA N5     N N N 117 
FDA C5X    C Y N 118 
FDA C6     C Y N 119 
FDA C7     C Y N 120 
FDA C7M    C N N 121 
FDA C8     C Y N 122 
FDA C8M    C N N 123 
FDA C9     C Y N 124 
FDA C9A    C Y N 125 
FDA N10    N N N 126 
FDA C10    C N N 127 
FDA "C1'"  C N N 128 
FDA "C2'"  C N S 129 
FDA "O2'"  O N N 130 
FDA "C3'"  C N S 131 
FDA "O3'"  O N N 132 
FDA "C4'"  C N R 133 
FDA "O4'"  O N N 134 
FDA "C5'"  C N N 135 
FDA "O5'"  O N N 136 
FDA P      P N R 137 
FDA O1P    O N N 138 
FDA O2P    O N N 139 
FDA O3P    O N N 140 
FDA HOA2   H N N 141 
FDA H51A   H N N 142 
FDA H52A   H N N 143 
FDA H4B    H N N 144 
FDA H3B    H N N 145 
FDA HO3A   H N N 146 
FDA H2B    H N N 147 
FDA HO2A   H N N 148 
FDA H1B    H N N 149 
FDA H8A    H N N 150 
FDA H61A   H N N 151 
FDA H62A   H N N 152 
FDA H2A    H N N 153 
FDA HN1    H N N 154 
FDA HN3    H N N 155 
FDA HN5    H N N 156 
FDA H6     H N N 157 
FDA HM71   H N N 158 
FDA HM72   H N N 159 
FDA HM73   H N N 160 
FDA HM81   H N N 161 
FDA HM82   H N N 162 
FDA HM83   H N N 163 
FDA H9     H N N 164 
FDA "H1'1" H N N 165 
FDA "H1'2" H N N 166 
FDA "H2'"  H N N 167 
FDA "HO2'" H N N 168 
FDA "H3'"  H N N 169 
FDA "HO3'" H N N 170 
FDA "H4'"  H N N 171 
FDA "HO4'" H N N 172 
FDA "H5'1" H N N 173 
FDA "H5'2" H N N 174 
FDA HOP2   H N N 175 
GLN N      N N N 176 
GLN CA     C N S 177 
GLN C      C N N 178 
GLN O      O N N 179 
GLN CB     C N N 180 
GLN CG     C N N 181 
GLN CD     C N N 182 
GLN OE1    O N N 183 
GLN NE2    N N N 184 
GLN OXT    O N N 185 
GLN H      H N N 186 
GLN H2     H N N 187 
GLN HA     H N N 188 
GLN HB2    H N N 189 
GLN HB3    H N N 190 
GLN HG2    H N N 191 
GLN HG3    H N N 192 
GLN HE21   H N N 193 
GLN HE22   H N N 194 
GLN HXT    H N N 195 
GLU N      N N N 196 
GLU CA     C N S 197 
GLU C      C N N 198 
GLU O      O N N 199 
GLU CB     C N N 200 
GLU CG     C N N 201 
GLU CD     C N N 202 
GLU OE1    O N N 203 
GLU OE2    O N N 204 
GLU OXT    O N N 205 
GLU H      H N N 206 
GLU H2     H N N 207 
GLU HA     H N N 208 
GLU HB2    H N N 209 
GLU HB3    H N N 210 
GLU HG2    H N N 211 
GLU HG3    H N N 212 
GLU HE2    H N N 213 
GLU HXT    H N N 214 
GLY N      N N N 215 
GLY CA     C N N 216 
GLY C      C N N 217 
GLY O      O N N 218 
GLY OXT    O N N 219 
GLY H      H N N 220 
GLY H2     H N N 221 
GLY HA2    H N N 222 
GLY HA3    H N N 223 
GLY HXT    H N N 224 
HIS N      N N N 225 
HIS CA     C N S 226 
HIS C      C N N 227 
HIS O      O N N 228 
HIS CB     C N N 229 
HIS CG     C Y N 230 
HIS ND1    N Y N 231 
HIS CD2    C Y N 232 
HIS CE1    C Y N 233 
HIS NE2    N Y N 234 
HIS OXT    O N N 235 
HIS H      H N N 236 
HIS H2     H N N 237 
HIS HA     H N N 238 
HIS HB2    H N N 239 
HIS HB3    H N N 240 
HIS HD1    H N N 241 
HIS HD2    H N N 242 
HIS HE1    H N N 243 
HIS HE2    H N N 244 
HIS HXT    H N N 245 
HOH O      O N N 246 
HOH H1     H N N 247 
HOH H2     H N N 248 
ILE N      N N N 249 
ILE CA     C N S 250 
ILE C      C N N 251 
ILE O      O N N 252 
ILE CB     C N S 253 
ILE CG1    C N N 254 
ILE CG2    C N N 255 
ILE CD1    C N N 256 
ILE OXT    O N N 257 
ILE H      H N N 258 
ILE H2     H N N 259 
ILE HA     H N N 260 
ILE HB     H N N 261 
ILE HG12   H N N 262 
ILE HG13   H N N 263 
ILE HG21   H N N 264 
ILE HG22   H N N 265 
ILE HG23   H N N 266 
ILE HD11   H N N 267 
ILE HD12   H N N 268 
ILE HD13   H N N 269 
ILE HXT    H N N 270 
LEU N      N N N 271 
LEU CA     C N S 272 
LEU C      C N N 273 
LEU O      O N N 274 
LEU CB     C N N 275 
LEU CG     C N N 276 
LEU CD1    C N N 277 
LEU CD2    C N N 278 
LEU OXT    O N N 279 
LEU H      H N N 280 
LEU H2     H N N 281 
LEU HA     H N N 282 
LEU HB2    H N N 283 
LEU HB3    H N N 284 
LEU HG     H N N 285 
LEU HD11   H N N 286 
LEU HD12   H N N 287 
LEU HD13   H N N 288 
LEU HD21   H N N 289 
LEU HD22   H N N 290 
LEU HD23   H N N 291 
LEU HXT    H N N 292 
LYS N      N N N 293 
LYS CA     C N S 294 
LYS C      C N N 295 
LYS O      O N N 296 
LYS CB     C N N 297 
LYS CG     C N N 298 
LYS CD     C N N 299 
LYS CE     C N N 300 
LYS NZ     N N N 301 
LYS OXT    O N N 302 
LYS H      H N N 303 
LYS H2     H N N 304 
LYS HA     H N N 305 
LYS HB2    H N N 306 
LYS HB3    H N N 307 
LYS HG2    H N N 308 
LYS HG3    H N N 309 
LYS HD2    H N N 310 
LYS HD3    H N N 311 
LYS HE2    H N N 312 
LYS HE3    H N N 313 
LYS HZ1    H N N 314 
LYS HZ2    H N N 315 
LYS HZ3    H N N 316 
LYS HXT    H N N 317 
MES O1     O N N 318 
MES C2     C N N 319 
MES C3     C N N 320 
MES N4     N N N 321 
MES C5     C N N 322 
MES C6     C N N 323 
MES C7     C N N 324 
MES C8     C N N 325 
MES S      S N N 326 
MES O1S    O N N 327 
MES O2S    O N N 328 
MES O3S    O N N 329 
MES H21    H N N 330 
MES H22    H N N 331 
MES H31    H N N 332 
MES H32    H N N 333 
MES HN4    H N N 334 
MES H51    H N N 335 
MES H52    H N N 336 
MES H61    H N N 337 
MES H62    H N N 338 
MES H71    H N N 339 
MES H72    H N N 340 
MES H81    H N N 341 
MES H82    H N N 342 
MET N      N N N 343 
MET CA     C N S 344 
MET C      C N N 345 
MET O      O N N 346 
MET CB     C N N 347 
MET CG     C N N 348 
MET SD     S N N 349 
MET CE     C N N 350 
MET OXT    O N N 351 
MET H      H N N 352 
MET H2     H N N 353 
MET HA     H N N 354 
MET HB2    H N N 355 
MET HB3    H N N 356 
MET HG2    H N N 357 
MET HG3    H N N 358 
MET HE1    H N N 359 
MET HE2    H N N 360 
MET HE3    H N N 361 
MET HXT    H N N 362 
PHE N      N N N 363 
PHE CA     C N S 364 
PHE C      C N N 365 
PHE O      O N N 366 
PHE CB     C N N 367 
PHE CG     C Y N 368 
PHE CD1    C Y N 369 
PHE CD2    C Y N 370 
PHE CE1    C Y N 371 
PHE CE2    C Y N 372 
PHE CZ     C Y N 373 
PHE OXT    O N N 374 
PHE H      H N N 375 
PHE H2     H N N 376 
PHE HA     H N N 377 
PHE HB2    H N N 378 
PHE HB3    H N N 379 
PHE HD1    H N N 380 
PHE HD2    H N N 381 
PHE HE1    H N N 382 
PHE HE2    H N N 383 
PHE HZ     H N N 384 
PHE HXT    H N N 385 
PRO N      N N N 386 
PRO CA     C N S 387 
PRO C      C N N 388 
PRO O      O N N 389 
PRO CB     C N N 390 
PRO CG     C N N 391 
PRO CD     C N N 392 
PRO OXT    O N N 393 
PRO H      H N N 394 
PRO HA     H N N 395 
PRO HB2    H N N 396 
PRO HB3    H N N 397 
PRO HG2    H N N 398 
PRO HG3    H N N 399 
PRO HD2    H N N 400 
PRO HD3    H N N 401 
PRO HXT    H N N 402 
SER N      N N N 403 
SER CA     C N S 404 
SER C      C N N 405 
SER O      O N N 406 
SER CB     C N N 407 
SER OG     O N N 408 
SER OXT    O N N 409 
SER H      H N N 410 
SER H2     H N N 411 
SER HA     H N N 412 
SER HB2    H N N 413 
SER HB3    H N N 414 
SER HG     H N N 415 
SER HXT    H N N 416 
THR N      N N N 417 
THR CA     C N S 418 
THR C      C N N 419 
THR O      O N N 420 
THR CB     C N R 421 
THR OG1    O N N 422 
THR CG2    C N N 423 
THR OXT    O N N 424 
THR H      H N N 425 
THR H2     H N N 426 
THR HA     H N N 427 
THR HB     H N N 428 
THR HG1    H N N 429 
THR HG21   H N N 430 
THR HG22   H N N 431 
THR HG23   H N N 432 
THR HXT    H N N 433 
TRP N      N N N 434 
TRP CA     C N S 435 
TRP C      C N N 436 
TRP O      O N N 437 
TRP CB     C N N 438 
TRP CG     C Y N 439 
TRP CD1    C Y N 440 
TRP CD2    C Y N 441 
TRP NE1    N Y N 442 
TRP CE2    C Y N 443 
TRP CE3    C Y N 444 
TRP CZ2    C Y N 445 
TRP CZ3    C Y N 446 
TRP CH2    C Y N 447 
TRP OXT    O N N 448 
TRP H      H N N 449 
TRP H2     H N N 450 
TRP HA     H N N 451 
TRP HB2    H N N 452 
TRP HB3    H N N 453 
TRP HD1    H N N 454 
TRP HE1    H N N 455 
TRP HE3    H N N 456 
TRP HZ2    H N N 457 
TRP HZ3    H N N 458 
TRP HH2    H N N 459 
TRP HXT    H N N 460 
TYR N      N N N 461 
TYR CA     C N S 462 
TYR C      C N N 463 
TYR O      O N N 464 
TYR CB     C N N 465 
TYR CG     C Y N 466 
TYR CD1    C Y N 467 
TYR CD2    C Y N 468 
TYR CE1    C Y N 469 
TYR CE2    C Y N 470 
TYR CZ     C Y N 471 
TYR OH     O N N 472 
TYR OXT    O N N 473 
TYR H      H N N 474 
TYR H2     H N N 475 
TYR HA     H N N 476 
TYR HB2    H N N 477 
TYR HB3    H N N 478 
TYR HD1    H N N 479 
TYR HD2    H N N 480 
TYR HE1    H N N 481 
TYR HE2    H N N 482 
TYR HH     H N N 483 
TYR HXT    H N N 484 
VAL N      N N N 485 
VAL CA     C N S 486 
VAL C      C N N 487 
VAL O      O N N 488 
VAL CB     C N N 489 
VAL CG1    C N N 490 
VAL CG2    C N N 491 
VAL OXT    O N N 492 
VAL H      H N N 493 
VAL H2     H N N 494 
VAL HA     H N N 495 
VAL HB     H N N 496 
VAL HG11   H N N 497 
VAL HG12   H N N 498 
VAL HG13   H N N 499 
VAL HG21   H N N 500 
VAL HG22   H N N 501 
VAL HG23   H N N 502 
VAL HXT    H N N 503 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
CYS N     CA     sing N N 70  
CYS N     H      sing N N 71  
CYS N     H2     sing N N 72  
CYS CA    C      sing N N 73  
CYS CA    CB     sing N N 74  
CYS CA    HA     sing N N 75  
CYS C     O      doub N N 76  
CYS C     OXT    sing N N 77  
CYS CB    SG     sing N N 78  
CYS CB    HB2    sing N N 79  
CYS CB    HB3    sing N N 80  
CYS SG    HG     sing N N 81  
CYS OXT   HXT    sing N N 82  
FDA PA    O1A    doub N N 83  
FDA PA    O2A    sing N N 84  
FDA PA    O5B    sing N N 85  
FDA PA    O3P    sing N N 86  
FDA O2A   HOA2   sing N N 87  
FDA O5B   C5B    sing N N 88  
FDA C5B   C4B    sing N N 89  
FDA C5B   H51A   sing N N 90  
FDA C5B   H52A   sing N N 91  
FDA C4B   O4B    sing N N 92  
FDA C4B   C3B    sing N N 93  
FDA C4B   H4B    sing N N 94  
FDA O4B   C1B    sing N N 95  
FDA C3B   O3B    sing N N 96  
FDA C3B   C2B    sing N N 97  
FDA C3B   H3B    sing N N 98  
FDA O3B   HO3A   sing N N 99  
FDA C2B   O2B    sing N N 100 
FDA C2B   C1B    sing N N 101 
FDA C2B   H2B    sing N N 102 
FDA O2B   HO2A   sing N N 103 
FDA C1B   N9A    sing N N 104 
FDA C1B   H1B    sing N N 105 
FDA N9A   C8A    sing Y N 106 
FDA N9A   C4A    sing Y N 107 
FDA C8A   N7A    doub Y N 108 
FDA C8A   H8A    sing N N 109 
FDA N7A   C5A    sing Y N 110 
FDA C5A   C6A    sing Y N 111 
FDA C5A   C4A    doub Y N 112 
FDA C6A   N6A    sing N N 113 
FDA C6A   N1A    doub Y N 114 
FDA N6A   H61A   sing N N 115 
FDA N6A   H62A   sing N N 116 
FDA N1A   C2A    sing Y N 117 
FDA C2A   N3A    doub Y N 118 
FDA C2A   H2A    sing N N 119 
FDA N3A   C4A    sing Y N 120 
FDA N1    C2     sing N N 121 
FDA N1    C10    sing N N 122 
FDA N1    HN1    sing N N 123 
FDA C2    O2     doub N N 124 
FDA C2    N3     sing N N 125 
FDA N3    C4     sing N N 126 
FDA N3    HN3    sing N N 127 
FDA C4    O4     doub N N 128 
FDA C4    C4X    sing N N 129 
FDA C4X   N5     sing N N 130 
FDA C4X   C10    doub N N 131 
FDA N5    C5X    sing N N 132 
FDA N5    HN5    sing N N 133 
FDA C5X   C6     doub Y N 134 
FDA C5X   C9A    sing Y N 135 
FDA C6    C7     sing Y N 136 
FDA C6    H6     sing N N 137 
FDA C7    C7M    sing N N 138 
FDA C7    C8     doub Y N 139 
FDA C7M   HM71   sing N N 140 
FDA C7M   HM72   sing N N 141 
FDA C7M   HM73   sing N N 142 
FDA C8    C8M    sing N N 143 
FDA C8    C9     sing Y N 144 
FDA C8M   HM81   sing N N 145 
FDA C8M   HM82   sing N N 146 
FDA C8M   HM83   sing N N 147 
FDA C9    C9A    doub Y N 148 
FDA C9    H9     sing N N 149 
FDA C9A   N10    sing N N 150 
FDA N10   C10    sing N N 151 
FDA N10   "C1'"  sing N N 152 
FDA "C1'" "C2'"  sing N N 153 
FDA "C1'" "H1'1" sing N N 154 
FDA "C1'" "H1'2" sing N N 155 
FDA "C2'" "O2'"  sing N N 156 
FDA "C2'" "C3'"  sing N N 157 
FDA "C2'" "H2'"  sing N N 158 
FDA "O2'" "HO2'" sing N N 159 
FDA "C3'" "O3'"  sing N N 160 
FDA "C3'" "C4'"  sing N N 161 
FDA "C3'" "H3'"  sing N N 162 
FDA "O3'" "HO3'" sing N N 163 
FDA "C4'" "O4'"  sing N N 164 
FDA "C4'" "C5'"  sing N N 165 
FDA "C4'" "H4'"  sing N N 166 
FDA "O4'" "HO4'" sing N N 167 
FDA "C5'" "O5'"  sing N N 168 
FDA "C5'" "H5'1" sing N N 169 
FDA "C5'" "H5'2" sing N N 170 
FDA "O5'" P      sing N N 171 
FDA P     O1P    doub N N 172 
FDA P     O2P    sing N N 173 
FDA P     O3P    sing N N 174 
FDA O2P   HOP2   sing N N 175 
GLN N     CA     sing N N 176 
GLN N     H      sing N N 177 
GLN N     H2     sing N N 178 
GLN CA    C      sing N N 179 
GLN CA    CB     sing N N 180 
GLN CA    HA     sing N N 181 
GLN C     O      doub N N 182 
GLN C     OXT    sing N N 183 
GLN CB    CG     sing N N 184 
GLN CB    HB2    sing N N 185 
GLN CB    HB3    sing N N 186 
GLN CG    CD     sing N N 187 
GLN CG    HG2    sing N N 188 
GLN CG    HG3    sing N N 189 
GLN CD    OE1    doub N N 190 
GLN CD    NE2    sing N N 191 
GLN NE2   HE21   sing N N 192 
GLN NE2   HE22   sing N N 193 
GLN OXT   HXT    sing N N 194 
GLU N     CA     sing N N 195 
GLU N     H      sing N N 196 
GLU N     H2     sing N N 197 
GLU CA    C      sing N N 198 
GLU CA    CB     sing N N 199 
GLU CA    HA     sing N N 200 
GLU C     O      doub N N 201 
GLU C     OXT    sing N N 202 
GLU CB    CG     sing N N 203 
GLU CB    HB2    sing N N 204 
GLU CB    HB3    sing N N 205 
GLU CG    CD     sing N N 206 
GLU CG    HG2    sing N N 207 
GLU CG    HG3    sing N N 208 
GLU CD    OE1    doub N N 209 
GLU CD    OE2    sing N N 210 
GLU OE2   HE2    sing N N 211 
GLU OXT   HXT    sing N N 212 
GLY N     CA     sing N N 213 
GLY N     H      sing N N 214 
GLY N     H2     sing N N 215 
GLY CA    C      sing N N 216 
GLY CA    HA2    sing N N 217 
GLY CA    HA3    sing N N 218 
GLY C     O      doub N N 219 
GLY C     OXT    sing N N 220 
GLY OXT   HXT    sing N N 221 
HIS N     CA     sing N N 222 
HIS N     H      sing N N 223 
HIS N     H2     sing N N 224 
HIS CA    C      sing N N 225 
HIS CA    CB     sing N N 226 
HIS CA    HA     sing N N 227 
HIS C     O      doub N N 228 
HIS C     OXT    sing N N 229 
HIS CB    CG     sing N N 230 
HIS CB    HB2    sing N N 231 
HIS CB    HB3    sing N N 232 
HIS CG    ND1    sing Y N 233 
HIS CG    CD2    doub Y N 234 
HIS ND1   CE1    doub Y N 235 
HIS ND1   HD1    sing N N 236 
HIS CD2   NE2    sing Y N 237 
HIS CD2   HD2    sing N N 238 
HIS CE1   NE2    sing Y N 239 
HIS CE1   HE1    sing N N 240 
HIS NE2   HE2    sing N N 241 
HIS OXT   HXT    sing N N 242 
HOH O     H1     sing N N 243 
HOH O     H2     sing N N 244 
ILE N     CA     sing N N 245 
ILE N     H      sing N N 246 
ILE N     H2     sing N N 247 
ILE CA    C      sing N N 248 
ILE CA    CB     sing N N 249 
ILE CA    HA     sing N N 250 
ILE C     O      doub N N 251 
ILE C     OXT    sing N N 252 
ILE CB    CG1    sing N N 253 
ILE CB    CG2    sing N N 254 
ILE CB    HB     sing N N 255 
ILE CG1   CD1    sing N N 256 
ILE CG1   HG12   sing N N 257 
ILE CG1   HG13   sing N N 258 
ILE CG2   HG21   sing N N 259 
ILE CG2   HG22   sing N N 260 
ILE CG2   HG23   sing N N 261 
ILE CD1   HD11   sing N N 262 
ILE CD1   HD12   sing N N 263 
ILE CD1   HD13   sing N N 264 
ILE OXT   HXT    sing N N 265 
LEU N     CA     sing N N 266 
LEU N     H      sing N N 267 
LEU N     H2     sing N N 268 
LEU CA    C      sing N N 269 
LEU CA    CB     sing N N 270 
LEU CA    HA     sing N N 271 
LEU C     O      doub N N 272 
LEU C     OXT    sing N N 273 
LEU CB    CG     sing N N 274 
LEU CB    HB2    sing N N 275 
LEU CB    HB3    sing N N 276 
LEU CG    CD1    sing N N 277 
LEU CG    CD2    sing N N 278 
LEU CG    HG     sing N N 279 
LEU CD1   HD11   sing N N 280 
LEU CD1   HD12   sing N N 281 
LEU CD1   HD13   sing N N 282 
LEU CD2   HD21   sing N N 283 
LEU CD2   HD22   sing N N 284 
LEU CD2   HD23   sing N N 285 
LEU OXT   HXT    sing N N 286 
LYS N     CA     sing N N 287 
LYS N     H      sing N N 288 
LYS N     H2     sing N N 289 
LYS CA    C      sing N N 290 
LYS CA    CB     sing N N 291 
LYS CA    HA     sing N N 292 
LYS C     O      doub N N 293 
LYS C     OXT    sing N N 294 
LYS CB    CG     sing N N 295 
LYS CB    HB2    sing N N 296 
LYS CB    HB3    sing N N 297 
LYS CG    CD     sing N N 298 
LYS CG    HG2    sing N N 299 
LYS CG    HG3    sing N N 300 
LYS CD    CE     sing N N 301 
LYS CD    HD2    sing N N 302 
LYS CD    HD3    sing N N 303 
LYS CE    NZ     sing N N 304 
LYS CE    HE2    sing N N 305 
LYS CE    HE3    sing N N 306 
LYS NZ    HZ1    sing N N 307 
LYS NZ    HZ2    sing N N 308 
LYS NZ    HZ3    sing N N 309 
LYS OXT   HXT    sing N N 310 
MES O1    C2     sing N N 311 
MES O1    C6     sing N N 312 
MES C2    C3     sing N N 313 
MES C2    H21    sing N N 314 
MES C2    H22    sing N N 315 
MES C3    N4     sing N N 316 
MES C3    H31    sing N N 317 
MES C3    H32    sing N N 318 
MES N4    C5     sing N N 319 
MES N4    C7     sing N N 320 
MES N4    HN4    sing N N 321 
MES C5    C6     sing N N 322 
MES C5    H51    sing N N 323 
MES C5    H52    sing N N 324 
MES C6    H61    sing N N 325 
MES C6    H62    sing N N 326 
MES C7    C8     sing N N 327 
MES C7    H71    sing N N 328 
MES C7    H72    sing N N 329 
MES C8    S      sing N N 330 
MES C8    H81    sing N N 331 
MES C8    H82    sing N N 332 
MES S     O1S    doub N N 333 
MES S     O2S    doub N N 334 
MES S     O3S    sing N N 335 
MET N     CA     sing N N 336 
MET N     H      sing N N 337 
MET N     H2     sing N N 338 
MET CA    C      sing N N 339 
MET CA    CB     sing N N 340 
MET CA    HA     sing N N 341 
MET C     O      doub N N 342 
MET C     OXT    sing N N 343 
MET CB    CG     sing N N 344 
MET CB    HB2    sing N N 345 
MET CB    HB3    sing N N 346 
MET CG    SD     sing N N 347 
MET CG    HG2    sing N N 348 
MET CG    HG3    sing N N 349 
MET SD    CE     sing N N 350 
MET CE    HE1    sing N N 351 
MET CE    HE2    sing N N 352 
MET CE    HE3    sing N N 353 
MET OXT   HXT    sing N N 354 
PHE N     CA     sing N N 355 
PHE N     H      sing N N 356 
PHE N     H2     sing N N 357 
PHE CA    C      sing N N 358 
PHE CA    CB     sing N N 359 
PHE CA    HA     sing N N 360 
PHE C     O      doub N N 361 
PHE C     OXT    sing N N 362 
PHE CB    CG     sing N N 363 
PHE CB    HB2    sing N N 364 
PHE CB    HB3    sing N N 365 
PHE CG    CD1    doub Y N 366 
PHE CG    CD2    sing Y N 367 
PHE CD1   CE1    sing Y N 368 
PHE CD1   HD1    sing N N 369 
PHE CD2   CE2    doub Y N 370 
PHE CD2   HD2    sing N N 371 
PHE CE1   CZ     doub Y N 372 
PHE CE1   HE1    sing N N 373 
PHE CE2   CZ     sing Y N 374 
PHE CE2   HE2    sing N N 375 
PHE CZ    HZ     sing N N 376 
PHE OXT   HXT    sing N N 377 
PRO N     CA     sing N N 378 
PRO N     CD     sing N N 379 
PRO N     H      sing N N 380 
PRO CA    C      sing N N 381 
PRO CA    CB     sing N N 382 
PRO CA    HA     sing N N 383 
PRO C     O      doub N N 384 
PRO C     OXT    sing N N 385 
PRO CB    CG     sing N N 386 
PRO CB    HB2    sing N N 387 
PRO CB    HB3    sing N N 388 
PRO CG    CD     sing N N 389 
PRO CG    HG2    sing N N 390 
PRO CG    HG3    sing N N 391 
PRO CD    HD2    sing N N 392 
PRO CD    HD3    sing N N 393 
PRO OXT   HXT    sing N N 394 
SER N     CA     sing N N 395 
SER N     H      sing N N 396 
SER N     H2     sing N N 397 
SER CA    C      sing N N 398 
SER CA    CB     sing N N 399 
SER CA    HA     sing N N 400 
SER C     O      doub N N 401 
SER C     OXT    sing N N 402 
SER CB    OG     sing N N 403 
SER CB    HB2    sing N N 404 
SER CB    HB3    sing N N 405 
SER OG    HG     sing N N 406 
SER OXT   HXT    sing N N 407 
THR N     CA     sing N N 408 
THR N     H      sing N N 409 
THR N     H2     sing N N 410 
THR CA    C      sing N N 411 
THR CA    CB     sing N N 412 
THR CA    HA     sing N N 413 
THR C     O      doub N N 414 
THR C     OXT    sing N N 415 
THR CB    OG1    sing N N 416 
THR CB    CG2    sing N N 417 
THR CB    HB     sing N N 418 
THR OG1   HG1    sing N N 419 
THR CG2   HG21   sing N N 420 
THR CG2   HG22   sing N N 421 
THR CG2   HG23   sing N N 422 
THR OXT   HXT    sing N N 423 
TRP N     CA     sing N N 424 
TRP N     H      sing N N 425 
TRP N     H2     sing N N 426 
TRP CA    C      sing N N 427 
TRP CA    CB     sing N N 428 
TRP CA    HA     sing N N 429 
TRP C     O      doub N N 430 
TRP C     OXT    sing N N 431 
TRP CB    CG     sing N N 432 
TRP CB    HB2    sing N N 433 
TRP CB    HB3    sing N N 434 
TRP CG    CD1    doub Y N 435 
TRP CG    CD2    sing Y N 436 
TRP CD1   NE1    sing Y N 437 
TRP CD1   HD1    sing N N 438 
TRP CD2   CE2    doub Y N 439 
TRP CD2   CE3    sing Y N 440 
TRP NE1   CE2    sing Y N 441 
TRP NE1   HE1    sing N N 442 
TRP CE2   CZ2    sing Y N 443 
TRP CE3   CZ3    doub Y N 444 
TRP CE3   HE3    sing N N 445 
TRP CZ2   CH2    doub Y N 446 
TRP CZ2   HZ2    sing N N 447 
TRP CZ3   CH2    sing Y N 448 
TRP CZ3   HZ3    sing N N 449 
TRP CH2   HH2    sing N N 450 
TRP OXT   HXT    sing N N 451 
TYR N     CA     sing N N 452 
TYR N     H      sing N N 453 
TYR N     H2     sing N N 454 
TYR CA    C      sing N N 455 
TYR CA    CB     sing N N 456 
TYR CA    HA     sing N N 457 
TYR C     O      doub N N 458 
TYR C     OXT    sing N N 459 
TYR CB    CG     sing N N 460 
TYR CB    HB2    sing N N 461 
TYR CB    HB3    sing N N 462 
TYR CG    CD1    doub Y N 463 
TYR CG    CD2    sing Y N 464 
TYR CD1   CE1    sing Y N 465 
TYR CD1   HD1    sing N N 466 
TYR CD2   CE2    doub Y N 467 
TYR CD2   HD2    sing N N 468 
TYR CE1   CZ     doub Y N 469 
TYR CE1   HE1    sing N N 470 
TYR CE2   CZ     sing Y N 471 
TYR CE2   HE2    sing N N 472 
TYR CZ    OH     sing N N 473 
TYR OH    HH     sing N N 474 
TYR OXT   HXT    sing N N 475 
VAL N     CA     sing N N 476 
VAL N     H      sing N N 477 
VAL N     H2     sing N N 478 
VAL CA    C      sing N N 479 
VAL CA    CB     sing N N 480 
VAL CA    HA     sing N N 481 
VAL C     O      doub N N 482 
VAL C     OXT    sing N N 483 
VAL CB    CG1    sing N N 484 
VAL CB    CG2    sing N N 485 
VAL CB    HB     sing N N 486 
VAL CG1   HG11   sing N N 487 
VAL CG1   HG12   sing N N 488 
VAL CG1   HG13   sing N N 489 
VAL CG2   HG21   sing N N 490 
VAL CG2   HG22   sing N N 491 
VAL CG2   HG23   sing N N 492 
VAL OXT   HXT    sing N N 493 
# 
_pdbx_audit_support.funding_organization   'Japan Science and Technology' 
_pdbx_audit_support.country                Japan 
_pdbx_audit_support.grant_number           JPMJSP2138 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   5h59 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 32 2 1' 
_space_group.name_Hall        
;P 32 2"
;
_space_group.IT_number        154 
_space_group.crystal_system   trigonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9KKH 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.016926 
_atom_sites.fract_transf_matrix[1][2]   0.009772 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.019545 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.005350 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
P ? ? 9.51135 5.44231 ? ? 1.42069  35.72801 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N     . SER A 1 3   ? 36.35109  -6.18785  22.06414  1.000 32.07862  ? 1009 SER A N     1 
ATOM   2    C CA    . SER A 1 3   ? 36.90376  -7.36479  21.40645  1.000 30.23821  ? 1009 SER A CA    1 
ATOM   3    C C     . SER A 1 3   ? 35.86004  -8.46591  21.34681  1.000 25.41928  ? 1009 SER A C     1 
ATOM   4    O O     . SER A 1 3   ? 34.72285  -8.29065  21.79649  1.000 27.54659  ? 1009 SER A O     1 
ATOM   5    C CB    . SER A 1 3   ? 38.11209  -7.89178  22.18258  1.000 33.45579  ? 1009 SER A CB    1 
ATOM   6    O OG    . SER A 1 3   ? 38.85781  -6.83801  22.76124  1.000 36.06267  ? 1009 SER A OG    1 
ATOM   7    N N     . LYS A 1 4   ? 36.25647  -9.60819  20.79715  1.000 19.49436  ? 1010 LYS A N     1 
ATOM   8    C CA    A LYS A 1 4   ? 35.37762  -10.76091 20.79144  0.820 15.80614  ? 1010 LYS A CA    1 
ATOM   9    C CA    B LYS A 1 4   ? 35.39851  -10.78324 20.78641  0.180 17.51727  ? 1010 LYS A CA    1 
ATOM   10   C C     . LYS A 1 4   ? 35.34076  -11.39738 22.18043  1.000 15.67246  ? 1010 LYS A C     1 
ATOM   11   O O     . LYS A 1 4   ? 36.32234  -11.37713 22.93298  1.000 17.95381  ? 1010 LYS A O     1 
ATOM   12   C CB    A LYS A 1 4   ? 35.82158  -11.76273 19.72567  0.820 15.19251  ? 1010 LYS A CB    1 
ATOM   13   C CB    B LYS A 1 4   ? 35.93472  -11.81770 19.79616  0.180 17.94549  ? 1010 LYS A CB    1 
ATOM   14   C CG    A LYS A 1 4   ? 35.62364  -11.27074 18.29225  0.820 14.12791  ? 1010 LYS A CG    1 
ATOM   15   C CG    B LYS A 1 4   ? 35.21754  -11.84153 18.45386  0.180 17.67123  ? 1010 LYS A CG    1 
ATOM   16   C CD    A LYS A 1 4   ? 36.12069  -12.30578 17.29916  0.820 15.22624  ? 1010 LYS A CD    1 
ATOM   17   C CD    B LYS A 1 4   ? 36.17462  -12.19478 17.32403  0.180 16.48388  ? 1010 LYS A CD    1 
ATOM   18   C CE    A LYS A 1 4   ? 36.06784  -11.80083 15.87954  0.820 16.21874  ? 1010 LYS A CE    1 
ATOM   19   C CE    B LYS A 1 4   ? 35.65506  -11.71099 15.98041  0.180 15.59225  ? 1010 LYS A CE    1 
ATOM   20   N NZ    A LYS A 1 4   ? 34.66989  -11.69752 15.42156  0.820 15.50981  ? 1010 LYS A NZ    1 
ATOM   21   N NZ    B LYS A 1 4   ? 35.95126  -12.67293 14.88214  0.180 15.22160  ? 1010 LYS A NZ    1 
ATOM   22   N N     . VAL A 1 5   ? 34.17763  -11.94575 22.51941  1.000 13.23443  ? 1011 VAL A N     1 
ATOM   23   C CA    . VAL A 1 5   ? 33.89473  -12.47296 23.85289  1.000 12.95275  ? 1011 VAL A CA    1 
ATOM   24   C C     . VAL A 1 5   ? 34.48878  -13.86685 23.98407  1.000 11.50578  ? 1011 VAL A C     1 
ATOM   25   O O     . VAL A 1 5   ? 34.27289  -14.73026 23.13140  1.000 11.69790  ? 1011 VAL A O     1 
ATOM   26   C CB    . VAL A 1 5   ? 32.37314  -12.51657 24.08355  1.000 14.49152  ? 1011 VAL A CB    1 
ATOM   27   C CG1   . VAL A 1 5   ? 32.04088  -13.16328 25.42497  1.000 14.88127  ? 1011 VAL A CG1   1 
ATOM   28   C CG2   . VAL A 1 5   ? 31.76219  -11.12872 23.96104  1.000 16.28616  ? 1011 VAL A CG2   1 
ATOM   29   N N     . SER A 1 6   ? 35.22040  -14.10604 25.06641  1.000 11.75950  ? 1012 SER A N     1 
ATOM   30   C CA    A SER A 1 6   ? 35.74575  -15.44181 25.30507  0.698 11.93299  ? 1012 SER A CA    1 
ATOM   31   C CA    B SER A 1 6   ? 35.74981  -15.43961 25.31603  0.302 12.18789  ? 1012 SER A CA    1 
ATOM   32   C C     . SER A 1 6   ? 34.61043  -16.43188 25.51986  1.000 11.48065  ? 1012 SER A C     1 
ATOM   33   O O     . SER A 1 6   ? 33.68045  -16.18170 26.29508  1.000 13.27436  ? 1012 SER A O     1 
ATOM   34   C CB    A SER A 1 6   ? 36.65271  -15.42680 26.52874  0.698 13.12585  ? 1012 SER A CB    1 
ATOM   35   C CB    B SER A 1 6   ? 36.64840  -15.41574 26.55258  0.302 13.43225  ? 1012 SER A CB    1 
ATOM   36   O OG    A SER A 1 6   ? 37.73322  -14.54684 26.31054  0.698 14.30164  ? 1012 SER A OG    1 
ATOM   37   O OG    B SER A 1 6   ? 37.15033  -16.70756 26.84677  0.302 14.57094  ? 1012 SER A OG    1 
ATOM   38   N N     . VAL A 1 7   ? 34.68795  -17.55827 24.82526  1.000 10.54981  ? 1013 VAL A N     1 
ATOM   39   C CA    . VAL A 1 7   ? 33.71853  -18.63108 24.96707  1.000 10.24619  ? 1013 VAL A CA    1 
ATOM   40   C C     . VAL A 1 7   ? 34.45671  -19.89422 25.36791  1.000 10.07855  ? 1013 VAL A C     1 
ATOM   41   O O     . VAL A 1 7   ? 35.63146  -20.08533 25.03238  1.000 11.66593  ? 1013 VAL A O     1 
ATOM   42   C CB    . VAL A 1 7   ? 32.92750  -18.87042 23.66992  1.000 10.54275  ? 1013 VAL A CB    1 
ATOM   43   C CG1   . VAL A 1 7   ? 32.02194  -17.70675 23.39467  1.000 11.89601  ? 1013 VAL A CG1   1 
ATOM   44   C CG2   . VAL A 1 7   ? 33.85601  -19.11837 22.49043  1.000 12.05095  ? 1013 VAL A CG2   1 
ATOM   45   N N     . ALA A 1 8   ? 33.74854  -20.76736 26.07571  1.000 9.44184   ? 1014 ALA A N     1 
ATOM   46   C CA    . ALA A 1 8   ? 34.28641  -22.03736 26.52423  1.000 9.62416   ? 1014 ALA A CA    1 
ATOM   47   C C     . ALA A 1 8   ? 33.15539  -23.04891 26.54624  1.000 8.96306   ? 1014 ALA A C     1 
ATOM   48   O O     . ALA A 1 8   ? 31.98912  -22.66776 26.69052  1.000 9.57751   ? 1014 ALA A O     1 
ATOM   49   C CB    . ALA A 1 8   ? 34.86120  -21.90343 27.93809  1.000 10.42332  ? 1014 ALA A CB    1 
ATOM   50   N N     . PRO A 1 9   ? 33.46323  -24.34334 26.42556  1.000 9.20069   ? 1015 PRO A N     1 
ATOM   51   C CA    . PRO A 1 9   ? 34.79281  -24.91406 26.20024  1.000 9.87924   ? 1015 PRO A CA    1 
ATOM   52   C C     . PRO A 1 9   ? 35.07672  -25.08964 24.71600  1.000 9.37748   ? 1015 PRO A C     1 
ATOM   53   O O     . PRO A 1 9   ? 34.19978  -25.49198 23.94995  1.000 9.82143   ? 1015 PRO A O     1 
ATOM   54   C CB    . PRO A 1 9   ? 34.68643  -26.26778 26.88648  1.000 10.60320  ? 1015 PRO A CB    1 
ATOM   55   C CG    . PRO A 1 9   ? 33.25456  -26.65432 26.70502  1.000 10.75478  ? 1015 PRO A CG    1 
ATOM   56   C CD    . PRO A 1 9   ? 32.44800  -25.38487 26.64096  1.000 9.98186   ? 1015 PRO A CD    1 
ATOM   57   N N     . LEU A 1 10  ? 36.30878  -24.80259 24.31037  1.000 9.48938   ? 1016 LEU A N     1 
ATOM   58   C CA    . LEU A 1 10  ? 36.62770  -24.86047 22.89214  1.000 11.27752  ? 1016 LEU A CA    1 
ATOM   59   C C     . LEU A 1 10  ? 36.57071  -26.27375 22.32837  1.000 9.40554   ? 1016 LEU A C     1 
ATOM   60   O O     . LEU A 1 10  ? 36.52600  -26.42443 21.10014  1.000 9.90032   ? 1016 LEU A O     1 
ATOM   61   C CB    . LEU A 1 10  ? 37.95790  -24.16488 22.62879  1.000 14.46078  ? 1016 LEU A CB    1 
ATOM   62   C CG    . LEU A 1 10  ? 37.79417  -22.63399 22.63395  1.000 17.35150  ? 1016 LEU A CG    1 
ATOM   63   C CD1   . LEU A 1 10  ? 39.13381  -21.95029 22.49554  1.000 19.06769  ? 1016 LEU A CD1   1 
ATOM   64   C CD2   . LEU A 1 10  ? 36.84422  -22.13644 21.54236  1.000 18.47479  ? 1016 LEU A CD2   1 
ATOM   65   N N     . HIS A 1 11  ? 36.50093  -27.30730 23.17333  1.000 9.56186   ? 1017 HIS A N     1 
ATOM   66   C CA    . HIS A 1 11  ? 36.28560  -28.65186 22.64694  1.000 10.53452  ? 1017 HIS A CA    1 
ATOM   67   C C     . HIS A 1 11  ? 34.95751  -28.79695 21.91664  1.000 10.16745  ? 1017 HIS A C     1 
ATOM   68   O O     . HIS A 1 11  ? 34.78104  -29.77984 21.19289  1.000 11.09043  ? 1017 HIS A O     1 
ATOM   69   C CB    . HIS A 1 11  ? 36.46837  -29.73478 23.72003  1.000 10.82287  ? 1017 HIS A CB    1 
ATOM   70   C CG    . HIS A 1 11  ? 35.38561  -29.79268 24.76219  1.000 10.71416  ? 1017 HIS A CG    1 
ATOM   71   N ND1   . HIS A 1 11  ? 35.62480  -29.49974 26.08891  1.000 10.50385  ? 1017 HIS A ND1   1 
ATOM   72   C CD2   . HIS A 1 11  ? 34.09115  -30.18994 24.70166  1.000 11.95236  ? 1017 HIS A CD2   1 
ATOM   73   C CE1   . HIS A 1 11  ? 34.52467  -29.69459 26.79636  1.000 10.96446  ? 1017 HIS A CE1   1 
ATOM   74   N NE2   . HIS A 1 11  ? 33.57552  -30.10671 25.97652  1.000 12.29647  ? 1017 HIS A NE2   1 
ATOM   75   N N     . LEU A 1 12  ? 34.03809  -27.83690 22.05052  1.000 9.83430   ? 1018 LEU A N     1 
ATOM   76   C CA    . LEU A 1 12  ? 32.82928  -27.87506 21.23079  1.000 10.24189  ? 1018 LEU A CA    1 
ATOM   77   C C     . LEU A 1 12  ? 33.11980  -27.71509 19.74320  1.000 10.54649  ? 1018 LEU A C     1 
ATOM   78   O O     . LEU A 1 12  ? 32.23617  -27.98838 18.92349  1.000 11.96713  ? 1018 LEU A O     1 
ATOM   79   C CB    . LEU A 1 12  ? 31.82890  -26.81092 21.68212  1.000 10.28409  ? 1018 LEU A CB    1 
ATOM   80   C CG    . LEU A 1 12  ? 31.27128  -27.01591 23.09552  1.000 11.28929  ? 1018 LEU A CG    1 
ATOM   81   C CD1   . LEU A 1 12  ? 30.20992  -25.97764 23.39325  1.000 11.62134  ? 1018 LEU A CD1   1 
ATOM   82   C CD2   . LEU A 1 12  ? 30.71469  -28.43157 23.28138  1.000 12.47960  ? 1018 LEU A CD2   1 
ATOM   83   N N     . GLU A 1 13  ? 34.32167  -27.27059 19.37945  1.000 9.54130   ? 1019 GLU A N     1 
ATOM   84   C CA    . GLU A 1 13  ? 34.70428  -27.17545 17.97798  1.000 10.44507  ? 1019 GLU A CA    1 
ATOM   85   C C     . GLU A 1 13  ? 35.23560  -28.48690 17.42143  1.000 11.18442  ? 1019 GLU A C     1 
ATOM   86   O O     . GLU A 1 13  ? 35.43184  -28.58875 16.20569  1.000 13.59168  ? 1019 GLU A O     1 
ATOM   87   C CB    . GLU A 1 13  ? 35.76211  -26.08342 17.79405  1.000 10.47619  ? 1019 GLU A CB    1 
ATOM   88   C CG    . GLU A 1 13  ? 35.32219  -24.70738 18.25022  1.000 10.29643  ? 1019 GLU A CG    1 
ATOM   89   C CD    . GLU A 1 13  ? 34.16757  -24.15449 17.42211  1.000 9.86764   ? 1019 GLU A CD    1 
ATOM   90   O OE1   . GLU A 1 13  ? 34.14603  -24.40350 16.18717  1.000 10.67135  ? 1019 GLU A OE1   1 
ATOM   91   O OE2   . GLU A 1 13  ? 33.30288  -23.45613 17.99980  1.000 10.19601  ? 1019 GLU A OE2   1 
ATOM   92   N N     . SER A 1 14  ? 35.46936  -29.49281 18.26555  1.000 11.47361  ? 1020 SER A N     1 
ATOM   93   C CA    . SER A 1 14  ? 36.18183  -30.67593 17.79395  1.000 12.94904  ? 1020 SER A CA    1 
ATOM   94   C C     . SER A 1 14  ? 35.32781  -31.60347 16.94419  1.000 14.46234  ? 1020 SER A C     1 
ATOM   95   O O     . SER A 1 14  ? 35.84948  -32.23287 16.01558  1.000 16.44106  ? 1020 SER A O     1 
ATOM   96   C CB    . SER A 1 14  ? 36.77354  -31.44298 18.96962  1.000 14.25998  ? 1020 SER A CB    1 
ATOM   97   O OG    . SER A 1 14  ? 37.63439  -30.61299 19.72748  1.000 17.20557  ? 1020 SER A OG    1 
ATOM   98   N N     . ALA A 1 15  ? 34.04320  -31.72861 17.25614  1.000 14.73060  ? 1021 ALA A N     1 
ATOM   99   C CA    . ALA A 1 15  ? 33.19165  -32.65798 16.52898  1.000 17.19297  ? 1021 ALA A CA    1 
ATOM   100  C C     . ALA A 1 15  ? 33.18028  -32.31377 15.04567  1.000 17.25522  ? 1021 ALA A C     1 
ATOM   101  O O     . ALA A 1 15  ? 33.12674  -31.14409 14.65950  1.000 18.46989  ? 1021 ALA A O     1 
ATOM   102  C CB    . ALA A 1 15  ? 31.76822  -32.60825 17.08179  1.000 19.03491  ? 1021 ALA A CB    1 
ATOM   103  N N     . LYS A 1 16  ? 33.25030  -33.34597 14.21148  1.000 19.29588  ? 1022 LYS A N     1 
ATOM   104  C CA    . LYS A 1 16  ? 33.27561  -33.16913 12.76619  1.000 21.21289  ? 1022 LYS A CA    1 
ATOM   105  C C     . LYS A 1 16  ? 31.89095  -33.24294 12.14061  1.000 18.91872  ? 1022 LYS A C     1 
ATOM   106  O O     . LYS A 1 16  ? 31.73044  -32.88118 10.96857  1.000 19.70168  ? 1022 LYS A O     1 
ATOM   107  C CB    . LYS A 1 16  ? 34.18314  -34.22828 12.12749  1.000 25.55832  ? 1022 LYS A CB    1 
ATOM   108  C CG    . LYS A 1 16  ? 35.67354  -34.01777 12.37708  1.000 33.90915  ? 1022 LYS A CG    1 
ATOM   109  C CD    . LYS A 1 16  ? 36.02347  -32.54302 12.44433  1.000 56.40558  ? 1022 LYS A CD    1 
ATOM   110  C CE    . LYS A 1 16  ? 37.25943  -32.21735 11.62172  1.000 66.11043  ? 1022 LYS A CE    1 
ATOM   111  N NZ    . LYS A 1 16  ? 38.48606  -32.17240 12.46451  1.000 77.73691  ? 1022 LYS A NZ    1 
ATOM   112  N N     A GLU A 1 17  ? 30.89390  -33.69720 12.88664  0.567 17.19397  ? 1023 GLU A N     1 
ATOM   113  N N     B GLU A 1 17  ? 30.89533  -33.71422 12.87909  0.433 17.76819  ? 1023 GLU A N     1 
ATOM   114  C CA    A GLU A 1 17  ? 29.53413  -33.82435 12.39797  0.567 16.84640  ? 1023 GLU A CA    1 
ATOM   115  C CA    B GLU A 1 17  ? 29.53771  -33.79424 12.37472  0.433 17.37617  ? 1023 GLU A CA    1 
ATOM   116  C C     A GLU A 1 17  ? 28.58791  -33.23512 13.42966  0.567 15.34488  ? 1023 GLU A C     1 
ATOM   117  C C     B GLU A 1 17  ? 28.58153  -33.25198 13.42434  0.433 15.86849  ? 1023 GLU A C     1 
ATOM   118  O O     A GLU A 1 17  ? 28.89711  -33.23250 14.62729  0.567 15.29899  ? 1023 GLU A O     1 
ATOM   119  O O     B GLU A 1 17  ? 28.87766  -33.29592 14.62424  0.433 15.80183  ? 1023 GLU A O     1 
ATOM   120  C CB    A GLU A 1 17  ? 29.17671  -35.30149 12.18099  0.567 20.29105  ? 1023 GLU A CB    1 
ATOM   121  C CB    B GLU A 1 17  ? 29.15365  -35.24114 12.02659  0.433 19.73210  ? 1023 GLU A CB    1 
ATOM   122  C CG    A GLU A 1 17  ? 29.97469  -35.98044 11.08188  0.567 24.45770  ? 1023 GLU A CG    1 
ATOM   123  C CG    B GLU A 1 17  ? 29.08277  -36.18607 13.21191  0.433 22.23427  ? 1023 GLU A CG    1 
ATOM   124  C CD    A GLU A 1 17  ? 29.70691  -35.37569 9.71848   0.567 28.78299  ? 1023 GLU A CD    1 
ATOM   125  C CD    B GLU A 1 17  ? 28.84683  -37.62649 12.79401  0.433 24.47355  ? 1023 GLU A CD    1 
ATOM   126  O OE1   A GLU A 1 17  ? 28.52286  -35.15015 9.39017   0.567 30.50203  ? 1023 GLU A OE1   1 
ATOM   127  O OE1   B GLU A 1 17  ? 29.43237  -38.06028 11.77946  0.433 25.23410  ? 1023 GLU A OE1   1 
ATOM   128  O OE2   A GLU A 1 17  ? 30.67879  -35.12406 8.97627   0.567 30.54315  ? 1023 GLU A OE2   1 
ATOM   129  O OE2   B GLU A 1 17  ? 28.07140  -38.32467 13.48082  0.433 25.26082  ? 1023 GLU A OE2   1 
ATOM   130  N N     . PRO A 1 18  ? 27.43386  -32.71797 13.00037  1.000 15.84003  ? 1024 PRO A N     1 
ATOM   131  C CA    . PRO A 1 18  ? 26.49635  -32.15591 13.96338  1.000 15.87047  ? 1024 PRO A CA    1 
ATOM   132  C C     . PRO A 1 18  ? 25.85340  -33.25762 14.78419  1.000 15.32540  ? 1024 PRO A C     1 
ATOM   133  O O     . PRO A 1 18  ? 25.59438  -34.36151 14.27492  1.000 16.30060  ? 1024 PRO A O     1 
ATOM   134  C CB    . PRO A 1 18  ? 25.45911  -31.45239 13.06983  1.000 17.57480  ? 1024 PRO A CB    1 
ATOM   135  C CG    . PRO A 1 18  ? 25.48185  -32.26002 11.83194  1.000 18.32794  ? 1024 PRO A CG    1 
ATOM   136  C CD    . PRO A 1 18  ? 26.93481  -32.58014 11.61833  1.000 17.35084  ? 1024 PRO A CD    1 
ATOM   137  N N     . PRO A 1 19  ? 25.57567  -33.00605 16.06043  1.000 15.29742  ? 1025 PRO A N     1 
ATOM   138  C CA    . PRO A 1 19  ? 24.81066  -33.98067 16.83999  1.000 14.57262  ? 1025 PRO A CA    1 
ATOM   139  C C     . PRO A 1 19  ? 23.40260  -34.08453 16.28100  1.000 13.58846  ? 1025 PRO A C     1 
ATOM   140  O O     . PRO A 1 19  ? 22.81644  -33.09025 15.85746  1.000 13.79893  ? 1025 PRO A O     1 
ATOM   141  C CB    . PRO A 1 19  ? 24.79114  -33.37432 18.25018  1.000 16.48355  ? 1025 PRO A CB    1 
ATOM   142  C CG    . PRO A 1 19  ? 25.83487  -32.29322 18.25668  1.000 18.63608  ? 1025 PRO A CG    1 
ATOM   143  C CD    . PRO A 1 19  ? 25.90982  -31.80384 16.84318  1.000 16.60739  ? 1025 PRO A CD    1 
ATOM   144  N N     . LEU A 1 20  ? 22.85799  -35.29952 16.27991  1.000 13.22252  ? 1026 LEU A N     1 
ATOM   145  C CA    . LEU A 1 20  ? 21.49326  -35.51983 15.81545  1.000 13.43382  ? 1026 LEU A CA    1 
ATOM   146  C C     . LEU A 1 20  ? 20.81284  -36.54003 16.71247  1.000 12.42399  ? 1026 LEU A C     1 
ATOM   147  O O     . LEU A 1 20  ? 21.33528  -37.64154 16.91284  1.000 13.37827  ? 1026 LEU A O     1 
ATOM   148  C CB    . LEU A 1 20  ? 21.46661  -36.02810 14.36882  1.000 15.79734  ? 1026 LEU A CB    1 
ATOM   149  C CG    . LEU A 1 20  ? 21.87247  -35.02529 13.29071  1.000 17.85588  ? 1026 LEU A CG    1 
ATOM   150  C CD1   . LEU A 1 20  ? 22.02379  -35.72285 11.95270  1.000 20.49783  ? 1026 LEU A CD1   1 
ATOM   151  C CD2   . LEU A 1 20  ? 20.86524  -33.89414 13.19976  1.000 15.94676  ? 1026 LEU A CD2   1 
ATOM   152  N N     . ASN A 1 21  ? 19.64391  -36.17655 17.24066  1.000 12.34824  ? 1027 ASN A N     1 
ATOM   153  C CA    . ASN A 1 21  ? 18.78086  -37.12514 17.94437  1.000 12.36414  ? 1027 ASN A CA    1 
ATOM   154  C C     . ASN A 1 21  ? 19.47578  -37.72845 19.15987  1.000 11.91430  ? 1027 ASN A C     1 
ATOM   155  O O     . ASN A 1 21  ? 19.24536  -38.88743 19.51937  1.000 13.53680  ? 1027 ASN A O     1 
ATOM   156  C CB    . ASN A 1 21  ? 18.29255  -38.20383 16.98150  1.000 13.75668  ? 1027 ASN A CB    1 
ATOM   157  C CG    . ASN A 1 21  ? 17.36773  -37.64434 15.93676  1.000 15.54696  ? 1027 ASN A CG    1 
ATOM   158  O OD1   . ASN A 1 21  ? 16.39428  -36.95831 16.25143  1.000 17.45109  ? 1027 ASN A OD1   1 
ATOM   159  N ND2   . ASN A 1 21  ? 17.74069  -37.82367 14.68140  1.000 17.06025  ? 1027 ASN A ND2   1 
ATOM   160  N N     . THR A 1 22  ? 20.31762  -36.92464 19.80880  1.000 11.51917  ? 1028 THR A N     1 
ATOM   161  C CA    . THR A 1 22  ? 20.99948  -37.35047 21.02599  1.000 11.43511  ? 1028 THR A CA    1 
ATOM   162  C C     . THR A 1 22  ? 19.99985  -37.81318 22.06954  1.000 11.91570  ? 1028 THR A C     1 
ATOM   163  O O     . THR A 1 22  ? 20.21457  -38.82740 22.74904  1.000 13.46546  ? 1028 THR A O     1 
ATOM   164  C CB    . THR A 1 22  ? 21.79645  -36.16282 21.55407  1.000 11.47603  ? 1028 THR A CB    1 
ATOM   165  O OG1   . THR A 1 22  ? 22.55086  -35.61162 20.46864  1.000 11.89525  ? 1028 THR A OG1   1 
ATOM   166  C CG2   . THR A 1 22  ? 22.72471  -36.57370 22.69126  1.000 12.68599  ? 1028 THR A CG2   1 
ATOM   167  N N     . TYR A 1 23  ? 18.90689  -37.07077 22.21931  1.000 11.51413  ? 1029 TYR A N     1 
ATOM   168  C CA    . TYR A 1 23  ? 17.79248  -37.46874 23.06143  1.000 11.55778  ? 1029 TYR A CA    1 
ATOM   169  C C     . TYR A 1 23  ? 16.56089  -37.64695 22.19187  1.000 12.23151  ? 1029 TYR A C     1 
ATOM   170  O O     . TYR A 1 23  ? 16.28857  -36.83774 21.29751  1.000 12.99782  ? 1029 TYR A O     1 
ATOM   171  C CB    . TYR A 1 23  ? 17.53410  -36.45924 24.18136  1.000 11.40836  ? 1029 TYR A CB    1 
ATOM   172  C CG    . TYR A 1 23  ? 18.61362  -36.51942 25.22039  1.000 11.49217  ? 1029 TYR A CG    1 
ATOM   173  C CD1   . TYR A 1 23  ? 19.79263  -35.80648 25.05105  1.000 11.38782  ? 1029 TYR A CD1   1 
ATOM   174  C CD2   . TYR A 1 23  ? 18.50070  -37.35000 26.32736  1.000 12.47667  ? 1029 TYR A CD2   1 
ATOM   175  C CE1   . TYR A 1 23  ? 20.81139  -35.87451 25.97759  1.000 12.83737  ? 1029 TYR A CE1   1 
ATOM   176  C CE2   . TYR A 1 23  ? 19.51345  -37.42307 27.26731  1.000 13.31742  ? 1029 TYR A CE2   1 
ATOM   177  C CZ    . TYR A 1 23  ? 20.67282  -36.68254 27.08246  1.000 13.34722  ? 1029 TYR A CZ    1 
ATOM   178  O OH    . TYR A 1 23  ? 21.70715  -36.73728 27.99192  1.000 15.47587  ? 1029 TYR A OH    1 
ATOM   179  N N     . LYS A 1 24  ? 15.83005  -38.71072 22.45984  1.000 13.72605  ? 1030 LYS A N     1 
ATOM   180  C CA    . LYS A 1 24  ? 14.68360  -39.12483 21.68181  1.000 14.89513  ? 1030 LYS A CA    1 
ATOM   181  C C     . LYS A 1 24  ? 13.42069  -38.96519 22.51478  1.000 15.32936  ? 1030 LYS A C     1 
ATOM   182  O O     . LYS A 1 24  ? 13.48398  -38.91118 23.74933  1.000 14.76670  ? 1030 LYS A O     1 
ATOM   183  C CB    . LYS A 1 24  ? 14.87152  -40.59573 21.29700  1.000 17.04194  ? 1030 LYS A CB    1 
ATOM   184  C CG    . LYS A 1 24  ? 15.94898  -40.79444 20.25204  1.000 20.87172  ? 1030 LYS A CG    1 
ATOM   185  C CD    . LYS A 1 24  ? 16.20052  -42.26393 20.00018  1.000 23.88673  ? 1030 LYS A CD    1 
ATOM   186  C CE    . LYS A 1 24  ? 17.47780  -42.48550 19.21817  1.000 27.02641  ? 1030 LYS A CE    1 
ATOM   187  N NZ    . LYS A 1 24  ? 17.68779  -43.93442 18.94303  1.000 30.45103  ? 1030 LYS A NZ    1 
ATOM   188  N N     . PRO A 1 25  ? 12.24986  -38.88900 21.86977  1.000 17.20137  ? 1031 PRO A N     1 
ATOM   189  C CA    . PRO A 1 25  ? 11.02641  -38.52819 22.60371  1.000 18.79662  ? 1031 PRO A CA    1 
ATOM   190  C C     . PRO A 1 25  ? 10.68653  -39.44346 23.76260  1.000 19.62010  ? 1031 PRO A C     1 
ATOM   191  O O     . PRO A 1 25  ? 10.11892  -38.97294 24.75586  1.000 21.56972  ? 1031 PRO A O     1 
ATOM   192  C CB    . PRO A 1 25  ? 9.95240   -38.56623 21.51025  1.000 20.25348  ? 1031 PRO A CB    1 
ATOM   193  C CG    . PRO A 1 25  ? 10.69139  -38.14239 20.30080  1.000 20.28071  ? 1031 PRO A CG    1 
ATOM   194  C CD    . PRO A 1 25  ? 12.01647  -38.86719 20.41421  1.000 18.40955  ? 1031 PRO A CD    1 
ATOM   195  N N     . LYS A 1 26  ? 10.99935  -40.73482 23.67911  1.000 20.12071  ? 1032 LYS A N     1 
ATOM   196  C CA    . LYS A 1 26  ? 10.62120  -41.62571 24.76613  1.000 21.45254  ? 1032 LYS A CA    1 
ATOM   197  C C     . LYS A 1 26  ? 11.49795  -41.46065 26.00245  1.000 20.50097  ? 1032 LYS A C     1 
ATOM   198  O O     . LYS A 1 26  ? 11.07262  -41.83664 27.09874  1.000 21.45464  ? 1032 LYS A O     1 
ATOM   199  C CB    . LYS A 1 26  ? 10.56867  -43.07339 24.27721  1.000 24.29595  ? 1032 LYS A CB    1 
ATOM   200  C CG    . LYS A 1 26  ? 9.36955   -43.32600 23.35756  1.000 28.92062  ? 1032 LYS A CG    1 
ATOM   201  C CD    . LYS A 1 26  ? 9.46389   -44.64134 22.60177  1.000 33.76167  ? 1032 LYS A CD    1 
ATOM   202  C CE    . LYS A 1 26  ? 8.44419   -45.64382 23.13137  1.000 37.63464  ? 1032 LYS A CE    1 
ATOM   203  N NZ    . LYS A 1 26  ? 9.01943   -46.59557 24.12479  1.000 39.73751  ? 1032 LYS A NZ    1 
ATOM   204  N N     . GLU A 1 27  ? 12.69444  -40.89458 25.86112  1.000 19.05354  ? 1033 GLU A N     1 
ATOM   205  C CA    . GLU A 1 27  ? 13.56047  -40.58669 27.00057  1.000 18.71769  ? 1033 GLU A CA    1 
ATOM   206  C C     . GLU A 1 27  ? 14.20339  -39.22773 26.78463  1.000 15.61067  ? 1033 GLU A C     1 
ATOM   207  O O     . GLU A 1 27  ? 15.39330  -39.12426 26.46432  1.000 14.37167  ? 1033 GLU A O     1 
ATOM   208  C CB    . GLU A 1 27  ? 14.61970  -41.67114 27.21165  1.000 22.94402  ? 1033 GLU A CB    1 
ATOM   209  C CG    . GLU A 1 27  ? 14.05650  -43.03881 27.52439  1.000 30.13201  ? 1033 GLU A CG    1 
ATOM   210  C CD    . GLU A 1 27  ? 15.09694  -44.12778 27.40644  1.000 37.18321  ? 1033 GLU A CD    1 
ATOM   211  O OE1   . GLU A 1 27  ? 15.13295  -45.00652 28.29375  1.000 39.60229  ? 1033 GLU A OE1   1 
ATOM   212  O OE2   . GLU A 1 27  ? 15.87941  -44.10244 26.43218  1.000 40.05186  ? 1033 GLU A OE2   1 
ATOM   213  N N     . PRO A 1 28  ? 13.44639  -38.15222 26.96830  1.000 13.87573  ? 1034 PRO A N     1 
ATOM   214  C CA    . PRO A 1 28  ? 14.00582  -36.81404 26.76101  1.000 12.94789  ? 1034 PRO A CA    1 
ATOM   215  C C     . PRO A 1 28  ? 15.02446  -36.47276 27.83166  1.000 11.79243  ? 1034 PRO A C     1 
ATOM   216  O O     . PRO A 1 28  ? 15.15036  -37.14527 28.85844  1.000 13.02118  ? 1034 PRO A O     1 
ATOM   217  C CB    . PRO A 1 28  ? 12.78500  -35.89409 26.86320  1.000 13.34587  ? 1034 PRO A CB    1 
ATOM   218  C CG    . PRO A 1 28  ? 11.59192  -36.79415 26.76915  1.000 15.56961  ? 1034 PRO A CG    1 
ATOM   219  C CD    . PRO A 1 28  ? 12.02512  -38.09943 27.33926  1.000 14.52775  ? 1034 PRO A CD    1 
ATOM   220  N N     . PHE A 1 29  ? 15.75409  -35.39518 27.57928  1.000 10.95979  ? 1035 PHE A N     1 
ATOM   221  C CA    . PHE A 1 29  ? 16.60726  -34.81854 28.59839  1.000 10.87900  ? 1035 PHE A CA    1 
ATOM   222  C C     . PHE A 1 29  ? 15.80179  -33.80794 29.40858  1.000 10.89008  ? 1035 PHE A C     1 
ATOM   223  O O     . PHE A 1 29  ? 15.16891  -32.91634 28.83803  1.000 11.60269  ? 1035 PHE A O     1 
ATOM   224  C CB    . PHE A 1 29  ? 17.81320  -34.11894 27.97101  1.000 11.38962  ? 1035 PHE A CB    1 
ATOM   225  C CG    . PHE A 1 29  ? 18.71214  -33.52801 29.00050  1.000 10.53835  ? 1035 PHE A CG    1 
ATOM   226  C CD1   . PHE A 1 29  ? 19.56528  -34.34377 29.73045  1.000 12.39275  ? 1035 PHE A CD1   1 
ATOM   227  C CD2   . PHE A 1 29  ? 18.63051  -32.18250 29.33249  1.000 10.62366  ? 1035 PHE A CD2   1 
ATOM   228  C CE1   . PHE A 1 29  ? 20.36490  -33.82535 30.73942  1.000 12.64393  ? 1035 PHE A CE1   1 
ATOM   229  C CE2   . PHE A 1 29  ? 19.42710  -31.65751 30.35476  1.000 11.23027  ? 1035 PHE A CE2   1 
ATOM   230  C CZ    . PHE A 1 29  ? 20.29082  -32.48683 31.05732  1.000 11.79452  ? 1035 PHE A CZ    1 
ATOM   231  N N     . THR A 1 30  ? 15.81576  -33.93471 30.73560  1.000 10.55402  ? 1036 THR A N     1 
ATOM   232  C CA    . THR A 1 30  ? 15.09585  -32.97933 31.57763  1.000 10.87735  ? 1036 THR A CA    1 
ATOM   233  C C     . THR A 1 30  ? 16.00603  -31.79034 31.83556  1.000 10.19070  ? 1036 THR A C     1 
ATOM   234  O O     . THR A 1 30  ? 16.89416  -31.84083 32.69456  1.000 11.10699  ? 1036 THR A O     1 
ATOM   235  C CB    . THR A 1 30  ? 14.61456  -33.60957 32.87601  1.000 12.27498  ? 1036 THR A CB    1 
ATOM   236  O OG1   . THR A 1 30  ? 13.79390  -34.74008 32.57131  1.000 14.11558  ? 1036 THR A OG1   1 
ATOM   237  C CG2   . THR A 1 30  ? 13.80358  -32.59201 33.67305  1.000 12.62741  ? 1036 THR A CG2   1 
ATOM   238  N N     . ALA A 1 31  ? 15.79136  -30.72542 31.07377  1.000 9.65040   ? 1037 ALA A N     1 
ATOM   239  C CA    . ALA A 1 31  ? 16.53524  -29.48308 31.17763  1.000 9.85072   ? 1037 ALA A CA    1 
ATOM   240  C C     . ALA A 1 31  ? 15.82772  -28.53540 32.14231  1.000 9.56004   ? 1037 ALA A C     1 
ATOM   241  O O     . ALA A 1 31  ? 14.69948  -28.78020 32.57903  1.000 10.48188  ? 1037 ALA A O     1 
ATOM   242  C CB    . ALA A 1 31  ? 16.68139  -28.84835 29.79584  1.000 11.14074  ? 1037 ALA A CB    1 
ATOM   243  N N     . THR A 1 32  ? 16.49824  -27.43346 32.47474  1.000 9.52394   ? 1038 THR A N     1 
ATOM   244  C CA    . THR A 1 32  ? 15.98262  -26.48841 33.45443  1.000 9.25058   ? 1038 THR A CA    1 
ATOM   245  C C     . THR A 1 32  ? 15.98301  -25.08775 32.86746  1.000 9.07655   ? 1038 THR A C     1 
ATOM   246  O O     . THR A 1 32  ? 16.98815  -24.64483 32.30153  1.000 9.90300   ? 1038 THR A O     1 
ATOM   247  C CB    . THR A 1 32  ? 16.81700  -26.52794 34.73035  1.000 9.60269   ? 1038 THR A CB    1 
ATOM   248  O OG1   . THR A 1 32  ? 16.80762  -27.86068 35.24391  1.000 10.10078  ? 1038 THR A OG1   1 
ATOM   249  C CG2   . THR A 1 32  ? 16.26343  -25.58006 35.77013  1.000 10.19313  ? 1038 THR A CG2   1 
ATOM   250  N N     . ILE A 1 33  ? 14.86240  -24.38656 33.02124  1.000 9.34006   ? 1039 ILE A N     1 
ATOM   251  C CA    . ILE A 1 33  ? 14.75711  -23.01126 32.56186  1.000 9.69499   ? 1039 ILE A CA    1 
ATOM   252  C C     . ILE A 1 33  ? 15.67505  -22.11760 33.37901  1.000 9.67781   ? 1039 ILE A C     1 
ATOM   253  O O     . ILE A 1 33  ? 15.66177  -22.14417 34.61903  1.000 10.32024  ? 1039 ILE A O     1 
ATOM   254  C CB    . ILE A 1 33  ? 13.30375  -22.53944 32.67144  1.000 10.44994  ? 1039 ILE A CB    1 
ATOM   255  C CG1   . ILE A 1 33  ? 12.40737  -23.33763 31.72604  1.000 11.99820  ? 1039 ILE A CG1   1 
ATOM   256  C CG2   . ILE A 1 33  ? 13.18051  -21.03845 32.42575  1.000 11.54824  ? 1039 ILE A CG2   1 
ATOM   257  C CD1   . ILE A 1 33  ? 12.46070  -22.86748 30.28465  1.000 14.49070  ? 1039 ILE A CD1   1 
ATOM   258  N N     . VAL A 1 34  ? 16.44503  -21.29384 32.67777  1.000 9.81199   ? 1040 VAL A N     1 
ATOM   259  C CA    . VAL A 1 34  ? 17.23887  -20.23486 33.28540  1.000 10.22605  ? 1040 VAL A CA    1 
ATOM   260  C C     . VAL A 1 34  ? 16.45761  -18.93568 33.34369  1.000 10.81814  ? 1040 VAL A C     1 
ATOM   261  O O     . VAL A 1 34  ? 16.40213  -18.27681 34.38401  1.000 11.75914  ? 1040 VAL A O     1 
ATOM   262  C CB    . VAL A 1 34  ? 18.56676  -20.04982 32.51364  1.000 11.01962  ? 1040 VAL A CB    1 
ATOM   263  C CG1   . VAL A 1 34  ? 19.35600  -18.86916 33.07580  1.000 12.26551  ? 1040 VAL A CG1   1 
ATOM   264  C CG2   . VAL A 1 34  ? 19.38735  -21.33100 32.51500  1.000 12.24480  ? 1040 VAL A CG2   1 
ATOM   265  N N     . SER A 1 35  ? 15.84371  -18.54535 32.22823  1.000 10.49759  ? 1041 SER A N     1 
ATOM   266  C CA    . SER A 1 35  ? 15.13014  -17.28076 32.16144  1.000 10.93301  ? 1041 SER A CA    1 
ATOM   267  C C     . SER A 1 35  ? 14.13984  -17.30675 31.00988  1.000 10.27765  ? 1041 SER A C     1 
ATOM   268  O O     . SER A 1 35  ? 14.31313  -18.04377 30.03183  1.000 10.49378  ? 1041 SER A O     1 
ATOM   269  C CB    . SER A 1 35  ? 16.09010  -16.10614 31.96916  1.000 11.77888  ? 1041 SER A CB    1 
ATOM   270  O OG    . SER A 1 35  ? 16.84061  -16.25847 30.77675  1.000 12.00208  ? 1041 SER A OG    1 
ATOM   271  N N     . VAL A 1 36  ? 13.10292  -16.48395 31.14722  1.000 10.65278  ? 1042 VAL A N     1 
ATOM   272  C CA    . VAL A 1 36  ? 12.12854  -16.21981 30.09539  1.000 10.62758  ? 1042 VAL A CA    1 
ATOM   273  C C     . VAL A 1 36  ? 11.85691  -14.72720 30.11837  1.000 10.82505  ? 1042 VAL A C     1 
ATOM   274  O O     . VAL A 1 36  ? 11.57659  -14.16220 31.18075  1.000 12.85827  ? 1042 VAL A O     1 
ATOM   275  C CB    . VAL A 1 36  ? 10.80592  -16.98215 30.31689  1.000 12.23022  ? 1042 VAL A CB    1 
ATOM   276  C CG1   . VAL A 1 36  ? 9.75278   -16.54021 29.29686  1.000 13.40552  ? 1042 VAL A CG1   1 
ATOM   277  C CG2   . VAL A 1 36  ? 11.02747  -18.47626 30.26811  1.000 12.52439  ? 1042 VAL A CG2   1 
ATOM   278  N N     . GLU A 1 37  ? 11.96374  -14.07768 28.96128  1.000 11.48481  ? 1043 GLU A N     1 
ATOM   279  C CA    A GLU A 1 37  ? 11.72463  -12.64652 28.87618  0.552 12.74313  ? 1043 GLU A CA    1 
ATOM   280  C CA    B GLU A 1 37  ? 11.72836  -12.64633 28.87401  0.448 12.41914  ? 1043 GLU A CA    1 
ATOM   281  C C     . GLU A 1 37  ? 11.00290  -12.33610 27.57642  1.000 12.22460  ? 1043 GLU A C     1 
ATOM   282  O O     . GLU A 1 37  ? 11.27505  -12.95210 26.54175  1.000 14.45316  ? 1043 GLU A O     1 
ATOM   283  C CB    A GLU A 1 37  ? 13.03756  -11.84795 28.91700  0.552 15.21933  ? 1043 GLU A CB    1 
ATOM   284  C CB    B GLU A 1 37  ? 13.05154  -11.87471 28.89453  0.448 13.93851  ? 1043 GLU A CB    1 
ATOM   285  C CG    A GLU A 1 37  ? 13.89287  -12.05360 30.16991  0.552 17.57929  ? 1043 GLU A CG    1 
ATOM   286  C CG    B GLU A 1 37  ? 13.91581  -12.13084 27.67837  0.448 15.26116  ? 1043 GLU A CG    1 
ATOM   287  C CD    A GLU A 1 37  ? 13.22931  -11.55494 31.44671  0.552 19.93516  ? 1043 GLU A CD    1 
ATOM   288  C CD    B GLU A 1 37  ? 15.33793  -11.65524 27.85205  0.448 16.39399  ? 1043 GLU A CD    1 
ATOM   289  O OE1   A GLU A 1 37  ? 12.36668  -10.65268 31.36359  0.552 21.32962  ? 1043 GLU A OE1   1 
ATOM   290  O OE1   B GLU A 1 37  ? 15.61482  -10.47820 27.53710  0.448 18.17427  ? 1043 GLU A OE1   1 
ATOM   291  O OE2   A GLU A 1 37  ? 13.58213  -12.05840 32.53655  0.552 20.43884  ? 1043 GLU A OE2   1 
ATOM   292  O OE2   B GLU A 1 37  ? 16.17926  -12.46396 28.29620  0.448 14.90868  ? 1043 GLU A OE2   1 
ATOM   293  N N     . SER A 1 38  ? 10.08863  -11.37691 27.63263  1.000 12.80049  ? 1044 SER A N     1 
ATOM   294  C CA    . SER A 1 38  ? 9.48076   -10.88006 26.41113  1.000 12.86397  ? 1044 SER A CA    1 
ATOM   295  C C     . SER A 1 38  ? 10.51404  -10.09996 25.61207  1.000 12.40738  ? 1044 SER A C     1 
ATOM   296  O O     . SER A 1 38  ? 11.29941  -9.32820  26.16823  1.000 13.83281  ? 1044 SER A O     1 
ATOM   297  C CB    . SER A 1 38  ? 8.32810   -9.94742  26.73041  1.000 15.02804  ? 1044 SER A CB    1 
ATOM   298  O OG    . SER A 1 38  ? 7.87791   -9.36130  25.52476  1.000 15.25877  ? 1044 SER A OG    1 
ATOM   299  N N     . LEU A 1 39  ? 10.50109  -10.29810 24.29804  1.000 11.59797  ? 1045 LEU A N     1 
ATOM   300  C CA    . LEU A 1 39  ? 11.37610  -9.58650  23.38489  1.000 11.94271  ? 1045 LEU A CA    1 
ATOM   301  C C     . LEU A 1 39  ? 10.71580  -8.36370  22.77395  1.000 13.00306  ? 1045 LEU A C     1 
ATOM   302  O O     . LEU A 1 39  ? 11.34698  -7.67792  21.96384  1.000 13.45309  ? 1045 LEU A O     1 
ATOM   303  C CB    . LEU A 1 39  ? 11.81240  -10.52210 22.26205  1.000 11.41170  ? 1045 LEU A CB    1 
ATOM   304  C CG    . LEU A 1 39  ? 12.80727  -11.59127 22.69731  1.000 11.63512  ? 1045 LEU A CG    1 
ATOM   305  C CD1   . LEU A 1 39  ? 12.91259  -12.64938 21.61545  1.000 12.00854  ? 1045 LEU A CD1   1 
ATOM   306  C CD2   . LEU A 1 39  ? 14.16900  -10.98100 22.98601  1.000 12.62596  ? 1045 LEU A CD2   1 
ATOM   307  N N     . VAL A 1 40  ? 9.45721   -8.08163  23.11320  1.000 13.10460  ? 1046 VAL A N     1 
ATOM   308  C CA    . VAL A 1 40  ? 8.66116   -7.14796  22.33498  1.000 13.37350  ? 1046 VAL A CA    1 
ATOM   309  C C     . VAL A 1 40  ? 8.04683   -6.08719  23.23522  1.000 14.87131  ? 1046 VAL A C     1 
ATOM   310  O O     . VAL A 1 40  ? 7.91528   -6.25761  24.45119  1.000 16.12968  ? 1046 VAL A O     1 
ATOM   311  C CB    . VAL A 1 40  ? 7.58106   -7.85521  21.48321  1.000 13.72152  ? 1046 VAL A CB    1 
ATOM   312  C CG1   . VAL A 1 40  ? 8.23373   -8.78955  20.47471  1.000 15.90142  ? 1046 VAL A CG1   1 
ATOM   313  C CG2   . VAL A 1 40  ? 6.58807   -8.60606  22.35270  1.000 15.12355  ? 1046 VAL A CG2   1 
ATOM   314  N N     . GLY A 1 41  ? 7.67997   -4.97435  22.60479  1.000 15.93112  ? 1047 GLY A N     1 
ATOM   315  C CA    . GLY A 1 41  ? 7.08840   -3.84923  23.28225  1.000 17.64175  ? 1047 GLY A CA    1 
ATOM   316  C C     . GLY A 1 41  ? 5.57615   -3.89073  23.25024  1.000 19.70125  ? 1047 GLY A C     1 
ATOM   317  O O     . GLY A 1 41  ? 4.96183   -4.78476  22.66072  1.000 19.11532  ? 1047 GLY A O     1 
ATOM   318  N N     . PRO A 1 42  ? 4.94496   -2.90114  23.88548  1.000 21.89994  ? 1048 PRO A N     1 
ATOM   319  C CA    . PRO A 1 42  ? 3.48883   -2.96577  24.08680  1.000 23.24799  ? 1048 PRO A CA    1 
ATOM   320  C C     . PRO A 1 42  ? 2.67179   -2.90202  22.80872  1.000 23.61588  ? 1048 PRO A C     1 
ATOM   321  O O     . PRO A 1 42  ? 1.52492   -3.36787  22.80951  1.000 24.92163  ? 1048 PRO A O     1 
ATOM   322  C CB    . PRO A 1 42  ? 3.20434   -1.76709  25.00199  1.000 24.17610  ? 1048 PRO A CB    1 
ATOM   323  C CG    . PRO A 1 42  ? 4.35220   -0.83379  24.76980  1.000 24.60985  ? 1048 PRO A CG    1 
ATOM   324  C CD    . PRO A 1 42  ? 5.54215   -1.71455  24.51995  1.000 23.00139  ? 1048 PRO A CD    1 
ATOM   325  N N     . LYS A 1 43  ? 3.20450   -2.34700  21.72582  1.000 24.02507  ? 1049 LYS A N     1 
ATOM   326  C CA    . LYS A 1 43  ? 2.44970   -2.26748  20.48464  1.000 24.36337  ? 1049 LYS A CA    1 
ATOM   327  C C     . LYS A 1 43  ? 2.58374   -3.51572  19.62239  1.000 22.63978  ? 1049 LYS A C     1 
ATOM   328  O O     . LYS A 1 43  ? 1.93808   -3.58912  18.57072  1.000 23.35975  ? 1049 LYS A O     1 
ATOM   329  C CB    . LYS A 1 43  ? 2.85339   -1.03413  19.67224  1.000 26.63234  ? 1049 LYS A CB    1 
ATOM   330  C CG    . LYS A 1 43  ? 2.57594   0.30060   20.34164  1.000 29.79166  ? 1049 LYS A CG    1 
ATOM   331  C CD    . LYS A 1 43  ? 3.28088   1.41163   19.57914  1.000 32.69136  ? 1049 LYS A CD    1 
ATOM   332  C CE    . LYS A 1 43  ? 2.57251   2.74369   19.73605  1.000 34.91973  ? 1049 LYS A CE    1 
ATOM   333  N NZ    . LYS A 1 43  ? 3.49387   3.88587   19.47584  1.000 36.41847  ? 1049 LYS A NZ    1 
ATOM   334  N N     . ALA A 1 44  ? 3.39464   -4.48917  20.02734  1.000 21.04472  ? 1050 ALA A N     1 
ATOM   335  C CA    . ALA A 1 44  ? 3.50865   -5.70425  19.23943  1.000 19.96127  ? 1050 ALA A CA    1 
ATOM   336  C C     . ALA A 1 44  ? 2.17359   -6.44549  19.24483  1.000 20.98208  ? 1050 ALA A C     1 
ATOM   337  O O     . ALA A 1 44  ? 1.50569   -6.51156  20.28324  1.000 21.92229  ? 1050 ALA A O     1 
ATOM   338  C CB    . ALA A 1 44  ? 4.59731   -6.60152  19.81958  1.000 18.83576  ? 1050 ALA A CB    1 
ATOM   339  N N     . PRO A 1 45  ? 1.75208   -7.01076  18.10945  1.000 23.39937  ? 1051 PRO A N     1 
ATOM   340  C CA    . PRO A 1 45  ? 0.44233   -7.68794  18.06603  1.000 24.48367  ? 1051 PRO A CA    1 
ATOM   341  C C     . PRO A 1 45  ? 0.35911   -8.93482  18.93077  1.000 24.95005  ? 1051 PRO A C     1 
ATOM   342  O O     . PRO A 1 45  ? -0.75210  -9.35930  19.27102  1.000 27.16296  ? 1051 PRO A O     1 
ATOM   343  C CB    . PRO A 1 45  ? 0.25248   -8.02487  16.57939  1.000 26.00219  ? 1051 PRO A CB    1 
ATOM   344  C CG    . PRO A 1 45  ? 1.29485   -7.23931  15.84431  1.000 25.95301  ? 1051 PRO A CG    1 
ATOM   345  C CD    . PRO A 1 45  ? 2.40957   -6.96711  16.79427  1.000 24.83442  ? 1051 PRO A CD    1 
ATOM   346  N N     . GLY A 1 46  ? 1.48590   -9.53329  19.29497  1.000 23.14982  ? 1052 GLY A N     1 
ATOM   347  C CA    . GLY A 1 46  ? 1.49151   -10.68221 20.17992  1.000 21.14046  ? 1052 GLY A CA    1 
ATOM   348  C C     . GLY A 1 46  ? 2.84031   -10.75002 20.85078  1.000 18.06254  ? 1052 GLY A C     1 
ATOM   349  O O     . GLY A 1 46  ? 3.75412   -9.98875  20.52589  1.000 18.25851  ? 1052 GLY A O     1 
ATOM   350  N N     . GLU A 1 47  ? 2.96072   -11.68702 21.78488  1.000 16.49084  ? 1053 GLU A N     1 
ATOM   351  C CA    A GLU A 1 47  ? 4.17370   -11.85694 22.56699  0.384 15.82119  ? 1053 GLU A CA    1 
ATOM   352  C CA    B GLU A 1 47  ? 4.18639   -11.84219 22.55720  0.616 15.25664  ? 1053 GLU A CA    1 
ATOM   353  C C     . GLU A 1 47  ? 5.12587   -12.82604 21.87221  1.000 13.92850  ? 1053 GLU A C     1 
ATOM   354  O O     . GLU A 1 47  ? 4.70227   -13.88747 21.40175  1.000 15.14975  ? 1053 GLU A O     1 
ATOM   355  C CB    A GLU A 1 47  ? 3.78865   -12.40765 23.93907  0.384 17.90224  ? 1053 GLU A CB    1 
ATOM   356  C CB    B GLU A 1 47  ? 3.89382   -12.31118 23.98759  0.616 17.05840  ? 1053 GLU A CB    1 
ATOM   357  C CG    A GLU A 1 47  ? 4.95121   -12.79627 24.80382  0.384 20.00282  ? 1053 GLU A CG    1 
ATOM   358  C CG    B GLU A 1 47  ? 5.15513   -12.44184 24.85115  0.616 19.11925  ? 1053 GLU A CG    1 
ATOM   359  C CD    A GLU A 1 47  ? 5.62171   -11.59232 25.40787  0.384 21.65359  ? 1053 GLU A CD    1 
ATOM   360  C CD    B GLU A 1 47  ? 4.89481   -12.91596 26.28141  0.616 20.80129  ? 1053 GLU A CD    1 
ATOM   361  O OE1   A GLU A 1 47  ? 6.26260   -10.83424 24.65235  0.384 21.57317  ? 1053 GLU A OE1   1 
ATOM   362  O OE1   B GLU A 1 47  ? 3.90884   -13.64372 26.52085  0.616 20.77411  ? 1053 GLU A OE1   1 
ATOM   363  O OE2   A GLU A 1 47  ? 5.49625   -11.39729 26.63466  0.384 22.95608  ? 1053 GLU A OE2   1 
ATOM   364  O OE2   B GLU A 1 47  ? 5.69531   -12.56539 27.17491  0.616 22.29743  ? 1053 GLU A OE2   1 
ATOM   365  N N     . THR A 1 48  ? 6.40157   -12.45478 21.80453  1.000 13.11280  ? 1054 THR A N     1 
ATOM   366  C CA    . THR A 1 48  ? 7.47930   -13.36453 21.44646  1.000 11.68753  ? 1054 THR A CA    1 
ATOM   367  C C     . THR A 1 48  ? 8.46674   -13.31431 22.59715  1.000 11.17800  ? 1054 THR A C     1 
ATOM   368  O O     . THR A 1 48  ? 8.81335   -12.22314 23.05811  1.000 12.17144  ? 1054 THR A O     1 
ATOM   369  C CB    . THR A 1 48  ? 8.16280   -12.93461 20.14785  1.000 12.10059  ? 1054 THR A CB    1 
ATOM   370  O OG1   . THR A 1 48  ? 7.20295   -12.97991 19.09238  1.000 13.52402  ? 1054 THR A OG1   1 
ATOM   371  C CG2   . THR A 1 48  ? 9.27813   -13.88467 19.78645  1.000 12.12320  ? 1054 THR A CG2   1 
ATOM   372  N N     . CYS A 1 49  ? 8.89279   -14.48408 23.07795  1.000 11.77370  ? 1055 CYS A N     1 
ATOM   373  C CA    A CYS A 1 49  ? 9.76115   -14.55245 24.24483  0.689 9.85957   ? 1055 CYS A CA    1 
ATOM   374  C CA    B CYS A 1 49  ? 9.72554   -14.60032 24.26178  0.311 17.73912  ? 1055 CYS A CA    1 
ATOM   375  C C     . CYS A 1 49  ? 11.08195  -15.22558 23.91564  1.000 11.60620  ? 1055 CYS A C     1 
ATOM   376  O O     . CYS A 1 49  ? 11.18812  -16.04680 22.99787  1.000 11.86855  ? 1055 CYS A O     1 
ATOM   377  C CB    A CYS A 1 49  ? 9.13695   -15.31429 25.40672  0.689 9.61402   ? 1055 CYS A CB    1 
ATOM   378  C CB    B CYS A 1 49  ? 8.94878   -15.36780 25.38776  0.311 29.79369  ? 1055 CYS A CB    1 
ATOM   379  S SG    A CYS A 1 49  ? 7.72236   -14.55677 26.10589  0.689 14.01514  ? 1055 CYS A SG    1 
ATOM   380  S SG    B CYS A 1 49  ? 8.45927   -17.13658 25.10205  0.311 14.53934  ? 1055 CYS A SG    1 
ATOM   381  N N     . HIS A 1 50  ? 12.10522  -14.84801 24.68002  1.000 10.59287  ? 1056 HIS A N     1 
ATOM   382  C CA    . HIS A 1 50  ? 13.42714  -15.45087 24.62259  1.000 9.66554   ? 1056 HIS A CA    1 
ATOM   383  C C     . HIS A 1 50  ? 13.53676  -16.38382 25.82196  1.000 9.58393   ? 1056 HIS A C     1 
ATOM   384  O O     . HIS A 1 50  ? 13.36788  -15.94681 26.97091  1.000 10.62742  ? 1056 HIS A O     1 
ATOM   385  C CB    . HIS A 1 50  ? 14.48629  -14.35785 24.70808  1.000 10.59659  ? 1056 HIS A CB    1 
ATOM   386  C CG    . HIS A 1 50  ? 15.86867  -14.83506 24.41224  1.000 10.39181  ? 1056 HIS A CG    1 
ATOM   387  N ND1   . HIS A 1 50  ? 16.29321  -15.13407 23.13333  1.000 10.72167  ? 1056 HIS A ND1   1 
ATOM   388  C CD2   . HIS A 1 50  ? 16.93197  -15.03660 25.22688  1.000 11.62717  ? 1056 HIS A CD2   1 
ATOM   389  C CE1   . HIS A 1 50  ? 17.55513  -15.51754 23.18239  1.000 11.16190  ? 1056 HIS A CE1   1 
ATOM   390  N NE2   . HIS A 1 50  ? 17.96864  -15.45974 24.43561  1.000 11.37963  ? 1056 HIS A NE2   1 
ATOM   391  N N     . ILE A 1 51  ? 13.75918  -17.66761 25.54799  1.000 10.00762  ? 1057 ILE A N     1 
ATOM   392  C CA    . ILE A 1 51  ? 13.79088  -18.73104 26.55501  1.000 10.72735  ? 1057 ILE A CA    1 
ATOM   393  C C     . ILE A 1 51  ? 15.22333  -19.23679 26.64766  1.000 9.91414   ? 1057 ILE A C     1 
ATOM   394  O O     . ILE A 1 51  ? 15.76487  -19.70194 25.64031  1.000 10.59667  ? 1057 ILE A O     1 
ATOM   395  C CB    . ILE A 1 51  ? 12.88851  -19.91103 26.14376  1.000 12.74127  ? 1057 ILE A CB    1 
ATOM   396  C CG1   . ILE A 1 51  ? 11.58397  -19.46094 25.48403  1.000 16.50187  ? 1057 ILE A CG1   1 
ATOM   397  C CG2   . ILE A 1 51  ? 12.70637  -20.85274 27.31925  1.000 14.56558  ? 1057 ILE A CG2   1 
ATOM   398  C CD1   . ILE A 1 51  ? 10.72721  -18.80600 26.45039  1.000 19.05020  ? 1057 ILE A CD1   1 
ATOM   399  N N     . VAL A 1 52  ? 15.83163  -19.19104 27.83553  1.000 10.15458  ? 1058 VAL A N     1 
ATOM   400  C CA    . VAL A 1 52  ? 17.17311  -19.72969 28.04890  1.000 9.60695   ? 1058 VAL A CA    1 
ATOM   401  C C     . VAL A 1 52  ? 17.04771  -21.01500 28.85859  1.000 9.37627   ? 1058 VAL A C     1 
ATOM   402  O O     . VAL A 1 52  ? 16.40151  -21.03005 29.91743  1.000 10.52465  ? 1058 VAL A O     1 
ATOM   403  C CB    . VAL A 1 52  ? 18.08626  -18.71571 28.75469  1.000 10.77147  ? 1058 VAL A CB    1 
ATOM   404  C CG1   . VAL A 1 52  ? 19.48571  -19.28646 28.91413  1.000 11.38130  ? 1058 VAL A CG1   1 
ATOM   405  C CG2   . VAL A 1 52  ? 18.12951  -17.41280 27.96657  1.000 12.38203  ? 1058 VAL A CG2   1 
ATOM   406  N N     . ILE A 1 53  ? 17.64996  -22.08826 28.35054  1.000 9.41588   ? 1059 ILE A N     1 
ATOM   407  C CA    . ILE A 1 53  ? 17.48732  -23.44493 28.86158  1.000 9.60599   ? 1059 ILE A CA    1 
ATOM   408  C C     . ILE A 1 53  ? 18.86161  -24.00947 29.19991  1.000 9.73658   ? 1059 ILE A C     1 
ATOM   409  O O     . ILE A 1 53  ? 19.75541  -24.03485 28.34159  1.000 9.93123   ? 1059 ILE A O     1 
ATOM   410  C CB    . ILE A 1 53  ? 16.82396  -24.33271 27.79553  1.000 10.38384  ? 1059 ILE A CB    1 
ATOM   411  C CG1   . ILE A 1 53  ? 15.47328  -23.74923 27.37047  1.000 12.32194  ? 1059 ILE A CG1   1 
ATOM   412  C CG2   . ILE A 1 53  ? 16.73322  -25.75883 28.28973  1.000 11.40611  ? 1059 ILE A CG2   1 
ATOM   413  C CD1   . ILE A 1 53  ? 14.87524  -24.43604 26.17014  1.000 14.33188  ? 1059 ILE A CD1   1 
ATOM   414  N N     . ASP A 1 54  ? 19.02032  -24.49189 30.43214  1.000 9.87740   ? 1060 ASP A N     1 
ATOM   415  C CA    . ASP A 1 54  ? 20.24594  -25.14666 30.87284  1.000 10.06337  ? 1060 ASP A CA    1 
ATOM   416  C C     . ASP A 1 54  ? 20.14547  -26.62681 30.52487  1.000 10.01755  ? 1060 ASP A C     1 
ATOM   417  O O     . ASP A 1 54  ? 19.34045  -27.35227 31.11409  1.000 10.68444  ? 1060 ASP A O     1 
ATOM   418  C CB    . ASP A 1 54  ? 20.42496  -24.90523 32.37298  1.000 11.59779  ? 1060 ASP A CB    1 
ATOM   419  C CG    . ASP A 1 54  ? 21.67428  -25.56688 32.95040  1.000 11.50390  ? 1060 ASP A CG    1 
ATOM   420  O OD1   . ASP A 1 54  ? 22.36483  -26.32652 32.25519  1.000 13.36359  ? 1060 ASP A OD1   1 
ATOM   421  O OD2   . ASP A 1 54  ? 21.98967  -25.27429 34.12258  1.000 15.40969  ? 1060 ASP A OD2   1 
ATOM   422  N N     . HIS A 1 55  ? 20.93057  -27.06592 29.53873  1.000 10.03744  ? 1061 HIS A N     1 
ATOM   423  C CA    . HIS A 1 55  ? 21.03989  -28.46962 29.16701  1.000 10.87618  ? 1061 HIS A CA    1 
ATOM   424  C C     . HIS A 1 55  ? 22.27059  -29.13028 29.76688  1.000 11.46276  ? 1061 HIS A C     1 
ATOM   425  O O     . HIS A 1 55  ? 22.49787  -30.32203 29.53937  1.000 12.34143  ? 1061 HIS A O     1 
ATOM   426  C CB    . HIS A 1 55  ? 21.01421  -28.64917 27.64232  1.000 11.30459  ? 1061 HIS A CB    1 
ATOM   427  C CG    . HIS A 1 55  ? 22.19332  -28.05783 26.93129  1.000 9.94329   ? 1061 HIS A CG    1 
ATOM   428  N ND1   . HIS A 1 55  ? 23.35182  -28.76863 26.70058  1.000 10.13557  ? 1061 HIS A ND1   1 
ATOM   429  C CD2   . HIS A 1 55  ? 22.37026  -26.84009 26.36226  1.000 10.11118  ? 1061 HIS A CD2   1 
ATOM   430  C CE1   . HIS A 1 55  ? 24.20028  -28.00283 26.03725  1.000 10.31470  ? 1061 HIS A CE1   1 
ATOM   431  N NE2   . HIS A 1 55  ? 23.63225  -26.82728 25.82431  1.000 9.89626   ? 1061 HIS A NE2   1 
ATOM   432  N N     . GLY A 1 56  ? 23.04942  -28.39084 30.55091  1.000 12.27860  ? 1062 GLY A N     1 
ATOM   433  C CA    . GLY A 1 56  ? 24.15930  -28.96294 31.28736  1.000 13.17383  ? 1062 GLY A CA    1 
ATOM   434  C C     . GLY A 1 56  ? 25.32575  -29.40970 30.43868  1.000 12.42787  ? 1062 GLY A C     1 
ATOM   435  O O     . GLY A 1 56  ? 26.24189  -30.05169 30.96580  1.000 13.60769  ? 1062 GLY A O     1 
ATOM   436  N N     . GLY A 1 57  ? 25.34587  -29.06215 29.15055  1.000 10.85410  ? 1063 GLY A N     1 
ATOM   437  C CA    . GLY A 1 57  ? 26.31163  -29.63146 28.24068  1.000 10.84945  ? 1063 GLY A CA    1 
ATOM   438  C C     . GLY A 1 57  ? 25.92605  -30.99253 27.71823  1.000 10.16174  ? 1063 GLY A C     1 
ATOM   439  O O     . GLY A 1 57  ? 26.69418  -31.58766 26.94842  1.000 10.70449  ? 1063 GLY A O     1 
ATOM   440  N N     . ASN A 1 58  ? 24.75945  -31.50409 28.11246  1.000 10.12282  ? 1064 ASN A N     1 
ATOM   441  C CA    . ASN A 1 58  ? 24.31952  -32.82527 27.68649  1.000 10.64535  ? 1064 ASN A CA    1 
ATOM   442  C C     . ASN A 1 58  ? 23.64182  -32.82624 26.32844  1.000 10.56372  ? 1064 ASN A C     1 
ATOM   443  O O     . ASN A 1 58  ? 23.51045  -33.89827 25.72417  1.000 11.14600  ? 1064 ASN A O     1 
ATOM   444  C CB    . ASN A 1 58  ? 23.34707  -33.39830 28.70813  1.000 12.30668  ? 1064 ASN A CB    1 
ATOM   445  C CG    . ASN A 1 58  ? 24.00196  -33.62437 30.03886  1.000 14.44351  ? 1064 ASN A CG    1 
ATOM   446  O OD1   . ASN A 1 58  ? 24.76859  -34.56717 30.20116  1.000 17.78935  ? 1064 ASN A OD1   1 
ATOM   447  N ND2   . ASN A 1 58  ? 23.72902  -32.74573 30.99709  1.000 15.00790  ? 1064 ASN A ND2   1 
ATOM   448  N N     . VAL A 1 59  ? 23.17954  -31.67214 25.85370  1.000 10.25406  ? 1065 VAL A N     1 
ATOM   449  C CA    . VAL A 1 59  ? 22.49457  -31.61074 24.56339  1.000 10.02200  ? 1065 VAL A CA    1 
ATOM   450  C C     . VAL A 1 59  ? 23.16205  -30.55435 23.68749  1.000 9.97814   ? 1065 VAL A C     1 
ATOM   451  O O     . VAL A 1 59  ? 22.52408  -29.56586 23.28561  1.000 10.08434  ? 1065 VAL A O     1 
ATOM   452  C CB    . VAL A 1 59  ? 20.97730  -31.40200 24.70894  1.000 10.53082  ? 1065 VAL A CB    1 
ATOM   453  C CG1   . VAL A 1 59  ? 20.28164  -31.88132 23.44130  1.000 11.16856  ? 1065 VAL A CG1   1 
ATOM   454  C CG2   . VAL A 1 59  ? 20.43467  -32.14727 25.94002  1.000 11.13887  ? 1065 VAL A CG2   1 
ATOM   455  N N     . PRO A 1 60  ? 24.43872  -30.72728 23.35632  1.000 9.59925   ? 1066 PRO A N     1 
ATOM   456  C CA    . PRO A 1 60  ? 25.10311  -29.77106 22.46981  1.000 9.92884   ? 1066 PRO A CA    1 
ATOM   457  C C     . PRO A 1 60  ? 24.50511  -29.82184 21.07074  1.000 9.21889   ? 1066 PRO A C     1 
ATOM   458  O O     . PRO A 1 60  ? 23.84071  -30.78277 20.66613  1.000 10.39286  ? 1066 PRO A O     1 
ATOM   459  C CB    . PRO A 1 60  ? 26.55725  -30.25814 22.45768  1.000 10.07626  ? 1066 PRO A CB    1 
ATOM   460  C CG    . PRO A 1 60  ? 26.42501  -31.74171 22.70803  1.000 10.51343  ? 1066 PRO A CG    1 
ATOM   461  C CD    . PRO A 1 60  ? 25.32750  -31.85441 23.70640  1.000 9.95924   ? 1066 PRO A CD    1 
ATOM   462  N N     . TYR A 1 61  ? 24.79558  -28.77038 20.31438  1.000 8.89481   ? 1067 TYR A N     1 
ATOM   463  C CA    . TYR A 1 61  ? 24.22134  -28.59590 18.99113  1.000 9.24398   ? 1067 TYR A CA    1 
ATOM   464  C C     . TYR A 1 61  ? 25.14752  -27.68930 18.19308  1.000 9.00146   ? 1067 TYR A C     1 
ATOM   465  O O     . TYR A 1 61  ? 26.07141  -27.06573 18.73192  1.000 9.39031   ? 1067 TYR A O     1 
ATOM   466  C CB    . TYR A 1 61  ? 22.81954  -27.96556 19.06575  1.000 9.41869   ? 1067 TYR A CB    1 
ATOM   467  C CG    . TYR A 1 61  ? 22.82557  -26.68333 19.86882  1.000 8.94384   ? 1067 TYR A CG    1 
ATOM   468  C CD1   . TYR A 1 61  ? 23.12569  -25.45392 19.27457  1.000 8.90226   ? 1067 TYR A CD1   1 
ATOM   469  C CD2   . TYR A 1 61  ? 22.58628  -26.70715 21.24067  1.000 9.13498   ? 1067 TYR A CD2   1 
ATOM   470  C CE1   . TYR A 1 61  ? 23.18061  -24.29237 20.01390  1.000 8.86057   ? 1067 TYR A CE1   1 
ATOM   471  C CE2   . TYR A 1 61  ? 22.64033  -25.54409 21.99293  1.000 9.21747   ? 1067 TYR A CE2   1 
ATOM   472  C CZ    . TYR A 1 61  ? 22.94030  -24.34202 21.37673  1.000 8.51582   ? 1067 TYR A CZ    1 
ATOM   473  O OH    . TYR A 1 61  ? 22.98929  -23.18829 22.13585  1.000 8.92982   ? 1067 TYR A OH    1 
ATOM   474  N N     . TRP A 1 62  ? 24.87692  -27.61023 16.89518  1.000 9.36016   ? 1068 TRP A N     1 
ATOM   475  C CA    . TRP A 1 62  ? 25.50453  -26.63411 16.02437  1.000 9.52417   ? 1068 TRP A CA    1 
ATOM   476  C C     . TRP A 1 62  ? 24.50133  -25.53993 15.68343  1.000 8.76772   ? 1068 TRP A C     1 
ATOM   477  O O     . TRP A 1 62  ? 23.28053  -25.73687 15.71821  1.000 9.53125   ? 1068 TRP A O     1 
ATOM   478  C CB    . TRP A 1 62  ? 26.00059  -27.29531 14.73818  1.000 9.70229   ? 1068 TRP A CB    1 
ATOM   479  C CG    . TRP A 1 62  ? 27.21678  -28.14040 14.90209  1.000 10.33876  ? 1068 TRP A CG    1 
ATOM   480  C CD1   . TRP A 1 62  ? 27.81590  -28.53574 16.06369  1.000 11.74048  ? 1068 TRP A CD1   1 
ATOM   481  C CD2   . TRP A 1 62  ? 27.99271  -28.69977 13.84263  1.000 11.31231  ? 1068 TRP A CD2   1 
ATOM   482  N NE1   . TRP A 1 62  ? 28.92285  -29.30644 15.78300  1.000 13.00127  ? 1068 TRP A NE1   1 
ATOM   483  C CE2   . TRP A 1 62  ? 29.04912  -29.42392 14.42436  1.000 12.40164  ? 1068 TRP A CE2   1 
ATOM   484  C CE3   . TRP A 1 62  ? 27.90028  -28.64634 12.44839  1.000 13.47129  ? 1068 TRP A CE3   1 
ATOM   485  C CZ2   . TRP A 1 62  ? 30.00311  -30.09735 13.65719  1.000 14.48586  ? 1068 TRP A CZ2   1 
ATOM   486  C CZ3   . TRP A 1 62  ? 28.84048  -29.31427 11.69183  1.000 15.21264  ? 1068 TRP A CZ3   1 
ATOM   487  C CH2   . TRP A 1 62  ? 29.88208  -30.02864 12.29659  1.000 15.94461  ? 1068 TRP A CH2   1 
ATOM   488  N N     . GLU A 1 63  ? 25.04291  -24.37640 15.33695  1.000 8.93541   ? 1069 GLU A N     1 
ATOM   489  C CA    . GLU A 1 63  ? 24.21093  -23.25881 14.92612  1.000 9.05725   ? 1069 GLU A CA    1 
ATOM   490  C C     . GLU A 1 63  ? 23.30715  -23.68243 13.77414  1.000 9.20436   ? 1069 GLU A C     1 
ATOM   491  O O     . GLU A 1 63  ? 23.72379  -24.40218 12.85824  1.000 9.87357   ? 1069 GLU A O     1 
ATOM   492  C CB    . GLU A 1 63  ? 25.08833  -22.07048 14.53488  1.000 9.95466   ? 1069 GLU A CB    1 
ATOM   493  C CG    . GLU A 1 63  ? 25.87330  -21.47063 15.70914  1.000 9.77064   ? 1069 GLU A CG    1 
ATOM   494  C CD    . GLU A 1 63  ? 27.11344  -22.26917 16.13708  1.000 9.29509   ? 1069 GLU A CD    1 
ATOM   495  O OE1   . GLU A 1 63  ? 27.59890  -23.13101 15.36642  1.000 10.19472  ? 1069 GLU A OE1   1 
ATOM   496  O OE2   . GLU A 1 63  ? 27.61988  -22.00689 17.25376  1.000 11.17357  ? 1069 GLU A OE2   1 
ATOM   497  N N     . GLY A 1 64  ? 22.04733  -23.24910 13.83834  1.000 9.37309   ? 1070 GLY A N     1 
ATOM   498  C CA    . GLY A 1 64  ? 21.07963  -23.56657 12.81459  1.000 10.09032  ? 1070 GLY A CA    1 
ATOM   499  C C     . GLY A 1 64  ? 20.24081  -24.79513 13.09172  1.000 9.53997   ? 1070 GLY A C     1 
ATOM   500  O O     . GLY A 1 64  ? 19.27928  -25.05069 12.35230  1.000 10.86299  ? 1070 GLY A O     1 
ATOM   501  N N     . GLN A 1 65  ? 20.55895  -25.56352 14.12980  1.000 9.34511   ? 1071 GLN A N     1 
ATOM   502  C CA    . GLN A 1 65  ? 19.76196  -26.72758 14.47004  1.000 9.62734   ? 1071 GLN A CA    1 
ATOM   503  C C     . GLN A 1 65  ? 18.55172  -26.32676 15.30415  1.000 9.50226   ? 1071 GLN A C     1 
ATOM   504  O O     . GLN A 1 65  ? 18.38376  -25.16528 15.69131  1.000 9.95847   ? 1071 GLN A O     1 
ATOM   505  C CB    . GLN A 1 65  ? 20.61825  -27.74770 15.20012  1.000 9.55477   ? 1071 GLN A CB    1 
ATOM   506  C CG    . GLN A 1 65  ? 21.69711  -28.33547 14.31954  1.000 9.55339   ? 1071 GLN A CG    1 
ATOM   507  C CD    . GLN A 1 65  ? 22.30122  -29.57248 14.93351  1.000 9.63205   ? 1071 GLN A CD    1 
ATOM   508  O OE1   . GLN A 1 65  ? 23.03882  -29.49282 15.92136  1.000 10.51902  ? 1071 GLN A OE1   1 
ATOM   509  N NE2   . GLN A 1 65  ? 21.96913  -30.73153 14.38449  1.000 10.45898  ? 1071 GLN A NE2   1 
ATOM   510  N N     . SER A 1 66  ? 17.69628  -27.31154 15.58001  1.000 9.86481   ? 1072 SER A N     1 
ATOM   511  C CA    . SER A 1 66  ? 16.48836  -27.12144 16.36679  1.000 10.14781  ? 1072 SER A CA    1 
ATOM   512  C C     . SER A 1 66  ? 16.52104  -28.04314 17.57960  1.000 9.40367   ? 1072 SER A C     1 
ATOM   513  O O     . SER A 1 66  ? 17.10091  -29.13273 17.54035  1.000 10.55500  ? 1072 SER A O     1 
ATOM   514  C CB    . SER A 1 66  ? 15.25729  -27.49622 15.53782  1.000 12.46930  ? 1072 SER A CB    1 
ATOM   515  O OG    . SER A 1 66  ? 15.02927  -26.52171 14.53689  1.000 15.30185  ? 1072 SER A OG    1 
ATOM   516  N N     . TYR A 1 67  ? 15.87614  -27.59733 18.64900  1.000 9.53814   ? 1073 TYR A N     1 
ATOM   517  C CA    . TYR A 1 67  ? 15.55408  -28.46572 19.76902  1.000 9.45625   ? 1073 TYR A CA    1 
ATOM   518  C C     . TYR A 1 67  ? 14.09250  -28.88392 19.65675  1.000 9.81140   ? 1073 TYR A C     1 
ATOM   519  O O     . TYR A 1 67  ? 13.24894  -28.12444 19.17814  1.000 10.78674  ? 1073 TYR A O     1 
ATOM   520  C CB    . TYR A 1 67  ? 15.71428  -27.70092 21.07739  1.000 10.48479  ? 1073 TYR A CB    1 
ATOM   521  C CG    . TYR A 1 67  ? 17.07964  -27.67481 21.72925  1.000 9.64649   ? 1073 TYR A CG    1 
ATOM   522  C CD1   . TYR A 1 67  ? 17.98295  -28.73291 21.62424  1.000 10.12187  ? 1073 TYR A CD1   1 
ATOM   523  C CD2   . TYR A 1 67  ? 17.43183  -26.59366 22.51121  1.000 10.21465  ? 1073 TYR A CD2   1 
ATOM   524  C CE1   . TYR A 1 67  ? 19.20835  -28.69481 22.28977  1.000 10.16735  ? 1073 TYR A CE1   1 
ATOM   525  C CE2   . TYR A 1 67  ? 18.63905  -26.54686 23.16797  1.000 10.87465  ? 1073 TYR A CE2   1 
ATOM   526  C CZ    . TYR A 1 67  ? 19.52551  -27.59569 23.06603  1.000 9.72780   ? 1073 TYR A CZ    1 
ATOM   527  O OH    . TYR A 1 67  ? 20.69924  -27.51605 23.77272  1.000 9.93535   ? 1073 TYR A OH    1 
ATOM   528  N N     . GLY A 1 68  ? 13.79485  -30.09000 20.12360  1.000 9.98728   ? 1074 GLY A N     1 
ATOM   529  C CA    . GLY A 1 68  ? 12.42259  -30.47842 20.37825  1.000 10.75536  ? 1074 GLY A CA    1 
ATOM   530  C C     . GLY A 1 68  ? 12.06235  -30.23635 21.83099  1.000 10.33142  ? 1074 GLY A C     1 
ATOM   531  O O     . GLY A 1 68  ? 12.89165  -30.37576 22.72557  1.000 10.49407  ? 1074 GLY A O     1 
ATOM   532  N N     . VAL A 1 69  ? 10.80897  -29.85528 22.05429  1.000 10.54574  ? 1075 VAL A N     1 
ATOM   533  C CA    . VAL A 1 69  ? 10.25448  -29.70751 23.39416  1.000 11.13230  ? 1075 VAL A CA    1 
ATOM   534  C C     . VAL A 1 69  ? 8.96632   -30.51072 23.44426  1.000 10.47025  ? 1075 VAL A C     1 
ATOM   535  O O     . VAL A 1 69  ? 8.11710   -30.38875 22.55197  1.000 11.52741  ? 1075 VAL A O     1 
ATOM   536  C CB    . VAL A 1 69  ? 9.98315   -28.23307 23.75393  1.000 11.20065  ? 1075 VAL A CB    1 
ATOM   537  C CG1   . VAL A 1 69  ? 9.34868   -28.12386 25.12704  1.000 11.79285  ? 1075 VAL A CG1   1 
ATOM   538  C CG2   . VAL A 1 69  ? 11.26299  -27.40565 23.67956  1.000 12.03699  ? 1075 VAL A CG2   1 
ATOM   539  N N     . ILE A 1 70  ? 8.82790   -31.34548 24.46934  1.000 10.64558  ? 1076 ILE A N     1 
ATOM   540  C CA    . ILE A 1 70  ? 7.60267   -32.10247 24.70355  1.000 11.03305  ? 1076 ILE A CA    1 
ATOM   541  C C     . ILE A 1 70  ? 6.85037   -31.40704 25.83255  1.000 10.99893  ? 1076 ILE A C     1 
ATOM   542  O O     . ILE A 1 70  ? 7.29013   -31.48681 26.99051  1.000 11.10786  ? 1076 ILE A O     1 
ATOM   543  C CB    . ILE A 1 70  ? 7.88924   -33.57007 25.04096  1.000 12.48111  ? 1076 ILE A CB    1 
ATOM   544  C CG1   . ILE A 1 70  ? 8.57082   -34.25447 23.86015  1.000 14.01419  ? 1076 ILE A CG1   1 
ATOM   545  C CG2   . ILE A 1 70  ? 6.59251   -34.29492 25.38010  1.000 13.27366  ? 1076 ILE A CG2   1 
ATOM   546  C CD1   . ILE A 1 70  ? 9.14342   -35.61014 24.17858  1.000 16.50866  ? 1076 ILE A CD1   1 
ATOM   547  N N     . PRO A 1 71  ? 5.77485   -30.68501 25.54997  1.000 11.62015  ? 1077 PRO A N     1 
ATOM   548  C CA    . PRO A 1 71  ? 5.05539   -30.01374 26.62362  1.000 11.92861  ? 1077 PRO A CA    1 
ATOM   549  C C     . PRO A 1 71  ? 4.35712   -31.03931 27.49984  1.000 11.64357  ? 1077 PRO A C     1 
ATOM   550  O O     . PRO A 1 71  ? 4.16186   -32.19413 27.09032  1.000 11.98429  ? 1077 PRO A O     1 
ATOM   551  C CB    . PRO A 1 71  ? 4.04827   -29.14338 25.85973  1.000 12.68331  ? 1077 PRO A CB    1 
ATOM   552  C CG    . PRO A 1 71  ? 3.76474   -29.92391 24.63070  1.000 12.72985  ? 1077 PRO A CG    1 
ATOM   553  C CD    . PRO A 1 71  ? 5.09421   -30.53221 24.24880  1.000 12.24750  ? 1077 PRO A CD    1 
ATOM   554  N N     . PRO A 1 72  ? 3.98139   -30.66476 28.71687  1.000 12.00074  ? 1078 PRO A N     1 
ATOM   555  C CA    A PRO A 1 72  ? 3.34122   -31.61223 29.63208  0.458 12.50307  ? 1078 PRO A CA    1 
ATOM   556  C CA    B PRO A 1 72  ? 3.35093   -31.63164 29.62141  0.542 12.37339  ? 1078 PRO A CA    1 
ATOM   557  C C     . PRO A 1 72  ? 1.94578   -31.99691 29.16578  1.000 13.12981  ? 1078 PRO A C     1 
ATOM   558  O O     . PRO A 1 72  ? 1.33366   -31.35090 28.30885  1.000 13.65015  ? 1078 PRO A O     1 
ATOM   559  C CB    A PRO A 1 72  ? 3.27207   -30.82500 30.94821  0.458 13.19992  ? 1078 PRO A CB    1 
ATOM   560  C CB    B PRO A 1 72  ? 3.33612   -30.90356 30.96720  0.542 13.08921  ? 1078 PRO A CB    1 
ATOM   561  C CG    A PRO A 1 72  ? 4.27832   -29.69508 30.77355  0.458 12.91600  ? 1078 PRO A CG    1 
ATOM   562  C CG    B PRO A 1 72  ? 3.36399   -29.46843 30.61062  0.542 12.49908  ? 1078 PRO A CG    1 
ATOM   563  C CD    A PRO A 1 72  ? 4.15370   -29.34341 29.33668  0.458 12.34493  ? 1078 PRO A CD    1 
ATOM   564  C CD    B PRO A 1 72  ? 4.21380   -29.36905 29.37177  0.542 12.03003  ? 1078 PRO A CD    1 
ATOM   565  N N     . GLY A 1 73  ? 1.44476   -33.07420 29.75677  1.000 14.74397  ? 1079 GLY A N     1 
ATOM   566  C CA    . GLY A 1 73  ? 0.08077   -33.50874 29.55242  1.000 16.01702  ? 1079 GLY A CA    1 
ATOM   567  C C     . GLY A 1 73  ? -0.02846  -34.69840 28.61559  1.000 16.90010  ? 1079 GLY A C     1 
ATOM   568  O O     . GLY A 1 73  ? 0.93849   -35.15566 27.99895  1.000 16.73549  ? 1079 GLY A O     1 
ATOM   569  N N     . GLU A 1 74  ? -1.25449  -35.19927 28.52369  1.000 18.98478  ? 1080 GLU A N     1 
ATOM   570  C CA    . GLU A 1 74  ? -1.58723  -36.28143 27.61574  1.000 22.69550  ? 1080 GLU A CA    1 
ATOM   571  C C     . GLU A 1 74  ? -1.74118  -35.76826 26.18893  1.000 23.30163  ? 1080 GLU A C     1 
ATOM   572  O O     . GLU A 1 74  ? -2.22138  -34.65695 25.94979  1.000 23.77929  ? 1080 GLU A O     1 
ATOM   573  C CB    . GLU A 1 74  ? -2.92586  -36.87801 28.03296  1.000 26.25844  ? 1080 GLU A CB    1 
ATOM   574  C CG    . GLU A 1 74  ? -3.19076  -38.25894 27.50315  1.000 30.94119  ? 1080 GLU A CG    1 
ATOM   575  C CD    . GLU A 1 74  ? -4.40170  -38.86587 28.15713  1.000 34.87925  ? 1080 GLU A CD    1 
ATOM   576  O OE1   . GLU A 1 74  ? -5.40834  -38.14101 28.29633  1.000 36.06629  ? 1080 GLU A OE1   1 
ATOM   577  O OE2   . GLU A 1 74  ? -4.34287  -40.04648 28.55401  1.000 37.54015  ? 1080 GLU A OE2   1 
ATOM   578  N N     . ASN A 1 75  ? -1.35336  -36.60416 25.23744  1.000 24.49555  ? 1081 ASN A N     1 
ATOM   579  C CA    . ASN A 1 75  ? -1.64552  -36.33002 23.83548  1.000 26.49876  ? 1081 ASN A CA    1 
ATOM   580  C C     . ASN A 1 75  ? -3.15650  -36.39072 23.64114  1.000 27.73907  ? 1081 ASN A C     1 
ATOM   581  O O     . ASN A 1 75  ? -3.75801  -37.44919 23.87164  1.000 27.94307  ? 1081 ASN A O     1 
ATOM   582  C CB    . ASN A 1 75  ? -0.95468  -37.38340 22.97271  1.000 28.14017  ? 1081 ASN A CB    1 
ATOM   583  C CG    . ASN A 1 75  ? -1.07908  -37.10799 21.48268  1.000 30.93941  ? 1081 ASN A CG    1 
ATOM   584  O OD1   . ASN A 1 75  ? -1.97111  -36.38581 21.03669  1.000 30.59810  ? 1081 ASN A OD1   1 
ATOM   585  N ND2   . ASN A 1 75  ? -0.16039  -37.67140 20.70590  1.000 33.38584  ? 1081 ASN A ND2   1 
ATOM   586  N N     . PRO A 1 76  ? -3.80842  -35.29691 23.23610  1.000 29.71872  ? 1082 PRO A N     1 
ATOM   587  C CA    . PRO A 1 76  ? -5.27515  -35.32610 23.08194  1.000 31.29257  ? 1082 PRO A CA    1 
ATOM   588  C C     . PRO A 1 76  ? -5.76743  -36.31849 22.04314  1.000 32.84416  ? 1082 PRO A C     1 
ATOM   589  O O     . PRO A 1 76  ? -6.92299  -36.75385 22.12118  1.000 33.78592  ? 1082 PRO A O     1 
ATOM   590  C CB    . PRO A 1 76  ? -5.61980  -33.88208 22.68586  1.000 31.93812  ? 1082 PRO A CB    1 
ATOM   591  C CG    . PRO A 1 76  ? -4.43776  -33.06858 23.12952  1.000 31.90465  ? 1082 PRO A CG    1 
ATOM   592  C CD    . PRO A 1 76  ? -3.24843  -33.96474 22.95289  1.000 30.78804  ? 1082 PRO A CD    1 
ATOM   593  N N     . LYS A 1 77  ? -4.93427  -36.68344 21.07169  1.000 34.07246  ? 1083 LYS A N     1 
ATOM   594  C CA    . LYS A 1 77  ? -5.30236  -37.63818 20.03850  1.000 35.59341  ? 1083 LYS A CA    1 
ATOM   595  C C     . LYS A 1 77  ? -4.85856  -39.05799 20.36077  1.000 38.33449  ? 1083 LYS A C     1 
ATOM   596  O O     . LYS A 1 77  ? -5.20361  -39.98206 19.61643  1.000 39.46166  ? 1083 LYS A O     1 
ATOM   597  C CB    . LYS A 1 77  ? -4.70494  -37.20930 18.69110  1.000 34.34380  ? 1083 LYS A CB    1 
ATOM   598  C CG    . LYS A 1 77  ? -5.22062  -35.86863 18.18036  1.000 38.16412  ? 1083 LYS A CG    1 
ATOM   599  C CD    . LYS A 1 77  ? -4.61177  -35.51569 16.82981  1.000 92.03157  ? 1083 LYS A CD    1 
ATOM   600  C CE    . LYS A 1 77  ? -5.07411  -34.14781 16.34451  1.000 100.73141 ? 1083 LYS A CE    1 
ATOM   601  N NZ    . LYS A 1 77  ? -6.54577  -34.08806 16.12124  1.000 71.52144  ? 1083 LYS A NZ    1 
ATOM   602  N N     . LYS A 1 78  ? -4.11453  -39.25303 21.44860  1.000 39.21571  ? 1084 LYS A N     1 
ATOM   603  C CA    . LYS A 1 78  ? -3.58378  -40.56381 21.81716  1.000 39.48959  ? 1084 LYS A CA    1 
ATOM   604  C C     . LYS A 1 78  ? -3.61316  -40.67153 23.33399  1.000 41.86123  ? 1084 LYS A C     1 
ATOM   605  O O     . LYS A 1 78  ? -2.64005  -40.32050 24.01429  1.000 42.31371  ? 1084 LYS A O     1 
ATOM   606  C CB    . LYS A 1 78  ? -2.16119  -40.74888 21.28777  1.000 37.06207  ? 1084 LYS A CB    1 
ATOM   607  C CG    . LYS A 1 78  ? -2.04867  -41.67163 20.08795  1.000 62.27592  ? 1084 LYS A CG    1 
ATOM   608  C CD    . LYS A 1 78  ? -0.59968  -41.82821 19.65221  1.000 79.47195  ? 1084 LYS A CD    1 
ATOM   609  C CE    . LYS A 1 78  ? -0.20646  -40.74773 18.65460  1.000 87.91895  ? 1084 LYS A CE    1 
ATOM   610  N NZ    . LYS A 1 78  ? 0.91864   -41.17290 17.77549  1.000 52.41979  ? 1084 LYS A NZ    1 
ATOM   611  N N     . PRO A 1 79  ? -4.72391  -41.14354 23.90236  1.000 43.33795  ? 1085 PRO A N     1 
ATOM   612  C CA    . PRO A 1 79  ? -4.81857  -41.24740 25.36397  1.000 43.29888  ? 1085 PRO A CA    1 
ATOM   613  C C     . PRO A 1 79  ? -3.70481  -42.11294 25.93418  1.000 42.17368  ? 1085 PRO A C     1 
ATOM   614  O O     . PRO A 1 79  ? -3.30722  -43.11898 25.34301  1.000 42.11563  ? 1085 PRO A O     1 
ATOM   615  C CB    . PRO A 1 79  ? -6.19641  -41.88725 25.58222  1.000 44.56931  ? 1085 PRO A CB    1 
ATOM   616  C CG    . PRO A 1 79  ? -6.52897  -42.52887 24.25637  1.000 45.00536  ? 1085 PRO A CG    1 
ATOM   617  C CD    . PRO A 1 79  ? -5.96965  -41.57551 23.25117  1.000 44.62583  ? 1085 PRO A CD    1 
ATOM   618  N N     . GLY A 1 80  ? -3.18868  -41.69565 27.08994  1.000 40.69704  ? 1086 GLY A N     1 
ATOM   619  C CA    . GLY A 1 80  ? -2.08105  -42.37113 27.72879  1.000 39.84887  ? 1086 GLY A CA    1 
ATOM   620  C C     . GLY A 1 80  ? -0.71662  -42.06238 27.15337  1.000 38.80328  ? 1086 GLY A C     1 
ATOM   621  O O     . GLY A 1 80  ? 0.29150   -42.47422 27.74221  1.000 40.48384  ? 1086 GLY A O     1 
ATOM   622  N N     . ALA A 1 81  ? -0.64292  -41.34313 26.02456  1.000 35.51611  ? 1087 ALA A N     1 
ATOM   623  C CA    . ALA A 1 81  ? 0.61844   -41.06345 25.36351  1.000 32.72680  ? 1087 ALA A CA    1 
ATOM   624  C C     . ALA A 1 81  ? 1.08550   -39.64906 25.67838  1.000 29.51377  ? 1087 ALA A C     1 
ATOM   625  O O     . ALA A 1 81  ? 0.27053   -38.76813 25.97035  1.000 29.01367  ? 1087 ALA A O     1 
ATOM   626  C CB    . ALA A 1 81  ? 0.45472   -41.19483 23.84708  1.000 33.34297  ? 1087 ALA A CB    1 
ATOM   627  N N     . PRO A 1 82  ? 2.39110   -39.40125 25.62479  1.000 26.69900  ? 1088 PRO A N     1 
ATOM   628  C CA    . PRO A 1 82  ? 2.88225   -38.03328 25.80830  1.000 25.32914  ? 1088 PRO A CA    1 
ATOM   629  C C     . PRO A 1 82  ? 2.49625   -37.16574 24.62416  1.000 21.88595  ? 1088 PRO A C     1 
ATOM   630  O O     . PRO A 1 82  ? 2.09935   -37.64812 23.55992  1.000 22.60730  ? 1088 PRO A O     1 
ATOM   631  C CB    . PRO A 1 82  ? 4.40635   -38.18353 25.88814  1.000 26.83206  ? 1088 PRO A CB    1 
ATOM   632  C CG    . PRO A 1 82  ? 4.71592   -39.60008 25.61003  1.000 27.91513  ? 1088 PRO A CG    1 
ATOM   633  C CD    . PRO A 1 82  ? 3.46846   -40.38810 25.44236  1.000 27.58645  ? 1088 PRO A CD    1 
ATOM   634  N N     . GLN A 1 83  ? 2.62123   -35.85947 24.82945  1.000 18.59728  ? 1089 GLN A N     1 
ATOM   635  C CA    . GLN A 1 83  ? 2.40736   -34.91087 23.75027  1.000 16.66685  ? 1089 GLN A CA    1 
ATOM   636  C C     . GLN A 1 83  ? 3.46258   -35.08124 22.66611  1.000 16.00584  ? 1089 GLN A C     1 
ATOM   637  O O     . GLN A 1 83  ? 4.57387   -35.56351 22.90791  1.000 16.58305  ? 1089 GLN A O     1 
ATOM   638  C CB    . GLN A 1 83  ? 2.49191   -33.48819 24.29068  1.000 15.67174  ? 1089 GLN A CB    1 
ATOM   639  C CG    . GLN A 1 83  ? 1.48166   -33.21986 25.36989  1.000 15.79943  ? 1089 GLN A CG    1 
ATOM   640  C CD    . GLN A 1 83  ? 0.24686   -32.51363 24.85859  1.000 15.52076  ? 1089 GLN A CD    1 
ATOM   641  O OE1   . GLN A 1 83  ? -0.18367  -32.71763 23.71447  1.000 16.19780  ? 1089 GLN A OE1   1 
ATOM   642  N NE2   . GLN A 1 83  ? -0.34625  -31.68865 25.71055  1.000 15.59749  ? 1089 GLN A NE2   1 
ATOM   643  N N     . ASN A 1 84  ? 3.10405   -34.65522 21.45813  1.000 15.22544  ? 1090 ASN A N     1 
ATOM   644  C CA    . ASN A 1 84  ? 4.05313   -34.64101 20.35682  1.000 15.39371  ? 1090 ASN A CA    1 
ATOM   645  C C     . ASN A 1 84  ? 5.11810   -33.57136 20.57541  1.000 13.95123  ? 1090 ASN A C     1 
ATOM   646  O O     . ASN A 1 84  ? 4.86478   -32.50857 21.15476  1.000 13.16401  ? 1090 ASN A O     1 
ATOM   647  C CB    . ASN A 1 84  ? 3.33406   -34.32150 19.05035  1.000 17.78276  ? 1090 ASN A CB    1 
ATOM   648  C CG    . ASN A 1 84  ? 2.31390   -35.37146 18.67552  1.000 21.01494  ? 1090 ASN A CG    1 
ATOM   649  O OD1   . ASN A 1 84  ? 2.49352   -36.55621 18.95061  1.000 21.52497  ? 1090 ASN A OD1   1 
ATOM   650  N ND2   . ASN A 1 84  ? 1.23030   -34.93964 18.04802  1.000 22.31912  ? 1090 ASN A ND2   1 
ATOM   651  N N     . VAL A 1 85  ? 6.32038   -33.86067 20.07395  1.000 13.54217  ? 1091 VAL A N     1 
ATOM   652  C CA    . VAL A 1 85  ? 7.39482   -32.87779 20.04670  1.000 12.55931  ? 1091 VAL A CA    1 
ATOM   653  C C     . VAL A 1 85  ? 6.98219   -31.66868 19.22484  1.000 12.59439  ? 1091 VAL A C     1 
ATOM   654  O O     . VAL A 1 85  ? 6.39863   -31.80169 18.14269  1.000 13.77883  ? 1091 VAL A O     1 
ATOM   655  C CB    . VAL A 1 85  ? 8.63748   -33.52745 19.41513  1.000 13.07080  ? 1091 VAL A CB    1 
ATOM   656  C CG1   . VAL A 1 85  ? 9.71760   -32.48988 19.11962  1.000 13.49264  ? 1091 VAL A CG1   1 
ATOM   657  C CG2   . VAL A 1 85  ? 9.18988   -34.62588 20.29240  1.000 14.92583  ? 1091 VAL A CG2   1 
ATOM   658  N N     . ARG A 1 86  ? 7.29543   -30.48009 19.72937  1.000 11.19923  ? 1092 ARG A N     1 
ATOM   659  C CA    . ARG A 1 86  ? 7.33808   -29.26724 18.92561  1.000 11.18037  ? 1092 ARG A CA    1 
ATOM   660  C C     . ARG A 1 86  ? 8.78849   -28.84866 18.74624  1.000 10.60293  ? 1092 ARG A C     1 
ATOM   661  O O     . ARG A 1 86  ? 9.56333   -28.84503 19.70605  1.000 11.26916  ? 1092 ARG A O     1 
ATOM   662  C CB    . ARG A 1 86  ? 6.58614   -28.11779 19.59685  1.000 11.68970  ? 1092 ARG A CB    1 
ATOM   663  C CG    . ARG A 1 86  ? 5.06927   -28.14956 19.43849  1.000 12.50688  ? 1092 ARG A CG    1 
ATOM   664  C CD    . ARG A 1 86  ? 4.39529   -29.24933 20.23584  1.000 12.84164  ? 1092 ARG A CD    1 
ATOM   665  N NE    . ARG A 1 86  ? 2.98014   -28.94570 20.39828  1.000 13.71721  ? 1092 ARG A NE    1 
ATOM   666  C CZ    . ARG A 1 86  ? 2.05353   -29.81493 20.77505  1.000 13.95654  ? 1092 ARG A CZ    1 
ATOM   667  N NH1   . ARG A 1 86  ? 2.35571   -31.07422 21.05401  1.000 14.52874  ? 1092 ARG A NH1   1 
ATOM   668  N NH2   . ARG A 1 86  ? 0.79012   -29.40959 20.86574  1.000 14.99189  ? 1092 ARG A NH2   1 
ATOM   669  N N     . LEU A 1 87  ? 9.14081   -28.47836 17.51960  1.000 10.81323  ? 1093 LEU A N     1 
ATOM   670  C CA    . LEU A 1 87  ? 10.49697  -28.05707 17.19997  1.000 10.65187  ? 1093 LEU A CA    1 
ATOM   671  C C     . LEU A 1 87  ? 10.63175  -26.54230 17.30090  1.000 10.01594  ? 1093 LEU A C     1 
ATOM   672  O O     . LEU A 1 87  ? 9.73636   -25.79465 16.89663  1.000 10.68985  ? 1093 LEU A O     1 
ATOM   673  C CB    . LEU A 1 87  ? 10.87824  -28.50753 15.78645  1.000 11.80669  ? 1093 LEU A CB    1 
ATOM   674  C CG    . LEU A 1 87  ? 10.99168  -30.02258 15.61151  1.000 13.01993  ? 1093 LEU A CG    1 
ATOM   675  C CD1   . LEU A 1 87  ? 11.12655  -30.36575 14.15811  1.000 15.95339  ? 1093 LEU A CD1   1 
ATOM   676  C CD2   . LEU A 1 87  ? 12.15811  -30.59813 16.40079  1.000 14.38066  ? 1093 LEU A CD2   1 
ATOM   677  N N     . TYR A 1 88  ? 11.78337  -26.09201 17.79776  1.000 9.86513   ? 1094 TYR A N     1 
ATOM   678  C CA    . TYR A 1 88  ? 12.10592  -24.67602 17.89665  1.000 10.24087  ? 1094 TYR A CA    1 
ATOM   679  C C     . TYR A 1 88  ? 13.52442  -24.45420 17.40245  1.000 9.98296   ? 1094 TYR A C     1 
ATOM   680  O O     . TYR A 1 88  ? 14.46332  -25.11510 17.86364  1.000 10.92241  ? 1094 TYR A O     1 
ATOM   681  C CB    . TYR A 1 88  ? 11.93121  -24.14184 19.33615  1.000 10.39413  ? 1094 TYR A CB    1 
ATOM   682  C CG    . TYR A 1 88  ? 10.47797  -24.17857 19.70688  1.000 10.41261  ? 1094 TYR A CG    1 
ATOM   683  C CD1   . TYR A 1 88  ? 9.61883   -23.17485 19.29327  1.000 10.16018  ? 1094 TYR A CD1   1 
ATOM   684  C CD2   . TYR A 1 88  ? 9.94379   -25.26316 20.38731  1.000 10.37462  ? 1094 TYR A CD2   1 
ATOM   685  C CE1   . TYR A 1 88  ? 8.25762   -23.23439 19.56162  1.000 10.96677  ? 1094 TYR A CE1   1 
ATOM   686  C CE2   . TYR A 1 88  ? 8.59161   -25.34129 20.67441  1.000 10.92377  ? 1094 TYR A CE2   1 
ATOM   687  C CZ    . TYR A 1 88  ? 7.74095   -24.32479 20.24869  1.000 11.01053  ? 1094 TYR A CZ    1 
ATOM   688  O OH    . TYR A 1 88  ? 6.38748   -24.40407 20.50204  1.000 12.00063  ? 1094 TYR A OH    1 
ATOM   689  N N     . SER A 1 89  ? 13.67172  -23.52618 16.46467  1.000 10.27933  ? 1095 SER A N     1 
ATOM   690  C CA    . SER A 1 89  ? 14.98664  -23.13669 15.98898  1.000 10.65673  ? 1095 SER A CA    1 
ATOM   691  C C     . SER A 1 89  ? 15.82411  -22.60975 17.13787  1.000 9.96296   ? 1095 SER A C     1 
ATOM   692  O O     . SER A 1 89  ? 15.40635  -21.71364 17.86998  1.000 11.63626  ? 1095 SER A O     1 
ATOM   693  C CB    . SER A 1 89  ? 14.85112  -22.01151 14.97520  1.000 12.13079  ? 1095 SER A CB    1 
ATOM   694  O OG    . SER A 1 89  ? 13.98944  -22.34916 13.91817  1.000 14.29134  ? 1095 SER A OG    1 
ATOM   695  N N     . ILE A 1 90  ? 17.03433  -23.12812 17.28775  1.000 9.69495   ? 1096 ILE A N     1 
ATOM   696  C CA    . ILE A 1 90  ? 17.87876  -22.61780 18.35280  1.000 9.79199   ? 1096 ILE A CA    1 
ATOM   697  C C     . ILE A 1 90  ? 18.36019  -21.22236 17.97601  1.000 8.99920   ? 1096 ILE A C     1 
ATOM   698  O O     . ILE A 1 90  ? 18.84899  -20.99506 16.85863  1.000 9.33051   ? 1096 ILE A O     1 
ATOM   699  C CB    . ILE A 1 90  ? 19.01186  -23.60662 18.65204  1.000 9.37067   ? 1096 ILE A CB    1 
ATOM   700  C CG1   . ILE A 1 90  ? 18.40757  -24.93235 19.13697  1.000 9.91773   ? 1096 ILE A CG1   1 
ATOM   701  C CG2   . ILE A 1 90  ? 19.96006  -23.03523 19.68666  1.000 9.75514   ? 1096 ILE A CG2   1 
ATOM   702  C CD1   . ILE A 1 90  ? 19.35610  -26.10289 19.11071  1.000 10.04551  ? 1096 ILE A CD1   1 
ATOM   703  N N     . ALA A 1 91  ? 18.22938  -20.28056 18.91021  1.000 8.92457   ? 1097 ALA A N     1 
ATOM   704  C CA    . ALA A 1 91  ? 18.54108  -18.87444 18.68847  1.000 9.32712   ? 1097 ALA A CA    1 
ATOM   705  C C     . ALA A 1 91  ? 19.89220  -18.49105 19.26242  1.000 8.67586   ? 1097 ALA A C     1 
ATOM   706  O O     . ALA A 1 91  ? 20.27451  -17.31741 19.20934  1.000 9.66076   ? 1097 ALA A O     1 
ATOM   707  C CB    . ALA A 1 91  ? 17.45499  -17.99204 19.31355  1.000 9.94473   ? 1097 ALA A CB    1 
ATOM   708  N N     . SER A 1 92  ? 20.61638  -19.45175 19.80994  1.000 8.82955   ? 1098 SER A N     1 
ATOM   709  C CA    . SER A 1 92  ? 21.91001  -19.24309 20.42814  1.000 8.66324   ? 1098 SER A CA    1 
ATOM   710  C C     . SER A 1 92  ? 23.00721  -19.93262 19.62125  1.000 7.86003   ? 1098 SER A C     1 
ATOM   711  O O     . SER A 1 92  ? 22.75730  -20.80358 18.78139  1.000 8.87450   ? 1098 SER A O     1 
ATOM   712  C CB    . SER A 1 92  ? 21.88386  -19.82639 21.84122  1.000 8.75202   ? 1098 SER A CB    1 
ATOM   713  O OG    . SER A 1 92  ? 21.23049  -21.08686 21.84005  1.000 8.77114   ? 1098 SER A OG    1 
ATOM   714  N N     . THR A 1 93  ? 24.24343  -19.53180 19.89830  1.000 8.05191   ? 1099 THR A N     1 
ATOM   715  C CA    . THR A 1 93  ? 25.37565  -20.28905 19.38523  1.000 8.28827   ? 1099 THR A CA    1 
ATOM   716  C C     . THR A 1 93  ? 25.53663  -21.55798 20.21450  1.000 8.08027   ? 1099 THR A C     1 
ATOM   717  O O     . THR A 1 93  ? 24.92597  -21.71718 21.27247  1.000 8.09018   ? 1099 THR A O     1 
ATOM   718  C CB    . THR A 1 93  ? 26.67483  -19.50904 19.52843  1.000 8.77564   ? 1099 THR A CB    1 
ATOM   719  O OG1   . THR A 1 93  ? 27.03955  -19.51810 20.91361  1.000 8.55063   ? 1099 THR A OG1   1 
ATOM   720  C CG2   . THR A 1 93  ? 26.54044  -18.10568 18.99716  1.000 9.11494   ? 1099 THR A CG2   1 
ATOM   721  N N     . ARG A 1 94  ? 26.42888  -22.43663 19.75983  1.000 8.00114   ? 1100 ARG A N     1 
ATOM   722  C CA    . ARG A 1 94  ? 26.73787  -23.64598 20.51526  1.000 8.57367   ? 1100 ARG A CA    1 
ATOM   723  C C     . ARG A 1 94  ? 27.23814  -23.34456 21.92452  1.000 8.20834   ? 1100 ARG A C     1 
ATOM   724  O O     . ARG A 1 94  ? 27.12920  -24.21031 22.80121  1.000 8.57304   ? 1100 ARG A O     1 
ATOM   725  C CB    . ARG A 1 94  ? 27.76496  -24.49735 19.76415  1.000 9.16857   ? 1100 ARG A CB    1 
ATOM   726  C CG    . ARG A 1 94  ? 29.15826  -23.90880 19.71256  1.000 9.69538   ? 1100 ARG A CG    1 
ATOM   727  C CD    . ARG A 1 94  ? 30.04731  -24.74741 18.81767  1.000 10.02323  ? 1100 ARG A CD    1 
ATOM   728  N NE    . ARG A 1 94  ? 29.61982  -24.65413 17.42692  1.000 10.25941  ? 1100 ARG A NE    1 
ATOM   729  C CZ    . ARG A 1 94  ? 30.07056  -25.42961 16.44996  1.000 11.05916  ? 1100 ARG A CZ    1 
ATOM   730  N NH1   . ARG A 1 94  ? 30.93455  -26.40415 16.68455  1.000 11.78654  ? 1100 ARG A NH1   1 
ATOM   731  N NH2   . ARG A 1 94  ? 29.65675  -25.21106 15.20535  1.000 12.82148  ? 1100 ARG A NH2   1 
ATOM   732  N N     . TYR A 1 95  ? 27.81334  -22.16262 22.15608  1.000 8.23061   ? 1101 TYR A N     1 
ATOM   733  C CA    . TYR A 1 95  ? 28.25600  -21.76913 23.49137  1.000 8.42338   ? 1101 TYR A CA    1 
ATOM   734  C C     . TYR A 1 95  ? 27.12506  -21.21413 24.33571  1.000 8.50439   ? 1101 TYR A C     1 
ATOM   735  O O     . TYR A 1 95  ? 27.19719  -21.26779 25.56928  1.000 8.93196   ? 1101 TYR A O     1 
ATOM   736  C CB    . TYR A 1 95  ? 29.42737  -20.77542 23.40910  1.000 8.60548   ? 1101 TYR A CB    1 
ATOM   737  C CG    . TYR A 1 95  ? 30.57645  -21.40106 22.66036  1.000 8.70721   ? 1101 TYR A CG    1 
ATOM   738  C CD1   . TYR A 1 95  ? 31.40194  -22.31794 23.29472  1.000 8.92092   ? 1101 TYR A CD1   1 
ATOM   739  C CD2   . TYR A 1 95  ? 30.77702  -21.15035 21.30406  1.000 8.75775   ? 1101 TYR A CD2   1 
ATOM   740  C CE1   . TYR A 1 95  ? 32.40527  -22.95888 22.62439  1.000 9.65928   ? 1101 TYR A CE1   1 
ATOM   741  C CE2   . TYR A 1 95  ? 31.79452  -21.78600 20.61463  1.000 9.33024   ? 1101 TYR A CE2   1 
ATOM   742  C CZ    . TYR A 1 95  ? 32.59719  -22.69911 21.28271  1.000 9.49402   ? 1101 TYR A CZ    1 
ATOM   743  O OH    . TYR A 1 95  ? 33.59347  -23.36449 20.62833  1.000 11.81258  ? 1101 TYR A OH    1 
ATOM   744  N N     . GLY A 1 96  ? 26.08191  -20.69895 23.70300  1.000 8.91081   ? 1102 GLY A N     1 
ATOM   745  C CA    . GLY A 1 96  ? 24.93122  -20.19513 24.41343  1.000 9.08883   ? 1102 GLY A CA    1 
ATOM   746  C C     . GLY A 1 96  ? 25.16657  -18.81403 24.98806  1.000 8.17401   ? 1102 GLY A C     1 
ATOM   747  O O     . GLY A 1 96  ? 26.26888  -18.24209 24.94298  1.000 8.89273   ? 1102 GLY A O     1 
ATOM   748  N N     . ASP A 1 97  ? 24.09078  -18.27538 25.55735  1.000 8.68995   ? 1103 ASP A N     1 
ATOM   749  C CA    . ASP A 1 97  ? 24.06860  -16.88637 25.98731  1.000 9.31098   ? 1103 ASP A CA    1 
ATOM   750  C C     . ASP A 1 97  ? 24.94265  -16.62533 27.20201  1.000 9.60197   ? 1103 ASP A C     1 
ATOM   751  O O     . ASP A 1 97  ? 25.22763  -15.46008 27.50552  1.000 10.65764  ? 1103 ASP A O     1 
ATOM   752  C CB    . ASP A 1 97  ? 22.63338  -16.44616 26.27472  1.000 9.47388   ? 1103 ASP A CB    1 
ATOM   753  C CG    . ASP A 1 97  ? 21.75454  -16.42485 25.03635  1.000 9.37974   ? 1103 ASP A CG    1 
ATOM   754  O OD1   . ASP A 1 97  ? 22.27043  -16.53146 23.89009  1.000 10.09338  ? 1103 ASP A OD1   1 
ATOM   755  O OD2   . ASP A 1 97  ? 20.52595  -16.28847 25.22898  1.000 10.11249  ? 1103 ASP A OD2   1 
ATOM   756  N N     A ASN A 1 98  ? 25.35605  -17.67782 27.90863  0.718 9.40870   ? 1104 ASN A N     1 
ATOM   757  N N     B ASN A 1 98  ? 25.36698  -17.66331 27.91063  0.282 10.35534  ? 1104 ASN A N     1 
ATOM   758  C CA    A ASN A 1 98  ? 26.27525  -17.57922 29.03740  0.718 9.73856   ? 1104 ASN A CA    1 
ATOM   759  C CA    B ASN A 1 98  ? 26.30385  -17.48657 29.00716  0.282 11.26299  ? 1104 ASN A CA    1 
ATOM   760  C C     A ASN A 1 98  ? 27.70790  -17.91097 28.63571  0.718 9.13730   ? 1104 ASN A C     1 
ATOM   761  C C     B ASN A 1 98  ? 27.70971  -17.92483 28.63568  0.282 10.36976  ? 1104 ASN A C     1 
ATOM   762  O O     A ASN A 1 98  ? 28.58899  -17.94782 29.50045  0.718 10.18016  ? 1104 ASN A O     1 
ATOM   763  O O     B ASN A 1 98  ? 28.56694  -18.04699 29.51642  0.282 10.96296  ? 1104 ASN A O     1 
ATOM   764  C CB    A ASN A 1 98  ? 25.80964  -18.49691 30.18993  0.718 10.27610  ? 1104 ASN A CB    1 
ATOM   765  C CB    B ASN A 1 98  ? 25.79641  -18.17087 30.27686  0.282 13.08940  ? 1104 ASN A CB    1 
ATOM   766  C CG    A ASN A 1 98  ? 26.26295  -18.02186 31.56465  0.718 11.39275  ? 1104 ASN A CG    1 
ATOM   767  C CG    B ASN A 1 98  ? 24.95331  -17.24230 31.12356  0.282 15.82199  ? 1104 ASN A CG    1 
ATOM   768  O OD1   A ASN A 1 98  ? 26.36886  -16.82577 31.82664  0.718 12.22448  ? 1104 ASN A OD1   1 
ATOM   769  O OD1   B ASN A 1 98  ? 24.16799  -16.45377 30.59471  0.282 16.22773  ? 1104 ASN A OD1   1 
ATOM   770  N ND2   A ASN A 1 98  ? 26.51346  -18.97485 32.45719  0.718 11.92140  ? 1104 ASN A ND2   1 
ATOM   771  N ND2   B ASN A 1 98  ? 25.10345  -17.33172 32.44043  0.282 18.45424  ? 1104 ASN A ND2   1 
ATOM   772  N N     . PHE A 1 99  ? 27.95743  -18.16586 27.34671  1.000 9.21704   ? 1105 PHE A N     1 
ATOM   773  C CA    . PHE A 1 99  ? 29.31080  -18.32867 26.81864  1.000 9.51134   ? 1105 PHE A CA    1 
ATOM   774  C C     . PHE A 1 99  ? 30.05001  -19.51318 27.42646  1.000 9.63973   ? 1105 PHE A C     1 
ATOM   775  O O     . PHE A 1 99  ? 31.28527  -19.52432 27.47537  1.000 10.15070  ? 1105 PHE A O     1 
ATOM   776  C CB    . PHE A 1 99  ? 30.12442  -17.03538 26.93789  1.000 10.42418  ? 1105 PHE A CB    1 
ATOM   777  C CG    . PHE A 1 99  ? 29.42156  -15.82420 26.37374  1.000 10.37669  ? 1105 PHE A CG    1 
ATOM   778  C CD1   . PHE A 1 99  ? 29.23022  -15.67895 25.00419  1.000 11.18316  ? 1105 PHE A CD1   1 
ATOM   779  C CD2   . PHE A 1 99  ? 28.94660  -14.82925 27.21542  1.000 12.00052  ? 1105 PHE A CD2   1 
ATOM   780  C CE1   . PHE A 1 99  ? 28.58408  -14.54929 24.49264  1.000 11.51159  ? 1105 PHE A CE1   1 
ATOM   781  C CE2   . PHE A 1 99  ? 28.30789  -13.71083 26.70947  1.000 13.25797  ? 1105 PHE A CE2   1 
ATOM   782  C CZ    . PHE A 1 99  ? 28.12985  -13.57441 25.35026  1.000 12.14239  ? 1105 PHE A CZ    1 
ATOM   783  N N     . ASP A 1 100 ? 29.29725  -20.53261 27.83889  1.000 9.14450   ? 1106 ASP A N     1 
ATOM   784  C CA    . ASP A 1 100 ? 29.83605  -21.61868 28.64057  1.000 9.35832   ? 1106 ASP A CA    1 
ATOM   785  C C     . ASP A 1 100 ? 29.47205  -23.01182 28.13422  1.000 8.54477   ? 1106 ASP A C     1 
ATOM   786  O O     . ASP A 1 100 ? 29.81515  -24.00316 28.79052  1.000 9.78028   ? 1106 ASP A O     1 
ATOM   787  C CB    . ASP A 1 100 ? 29.41900  -21.46345 30.11400  1.000 10.07826  ? 1106 ASP A CB    1 
ATOM   788  C CG    . ASP A 1 100 ? 27.91706  -21.61376 30.33343  1.000 9.96293   ? 1106 ASP A CG    1 
ATOM   789  O OD1   . ASP A 1 100 ? 27.16271  -21.78881 29.34158  1.000 9.69925   ? 1106 ASP A OD1   1 
ATOM   790  O OD2   . ASP A 1 100 ? 27.50747  -21.55247 31.52077  1.000 11.03198  ? 1106 ASP A OD2   1 
ATOM   791  N N     . GLY A 1 101 ? 28.77829  -23.12621 27.00308  1.000 8.81832   ? 1107 GLY A N     1 
ATOM   792  C CA    . GLY A 1 101 ? 28.42961  -24.43870 26.50878  1.000 9.15609   ? 1107 GLY A CA    1 
ATOM   793  C C     . GLY A 1 101 ? 27.40119  -25.19113 27.31107  1.000 9.52744   ? 1107 GLY A C     1 
ATOM   794  O O     . GLY A 1 101 ? 27.25426  -26.40231 27.11392  1.000 11.52908  ? 1107 GLY A O     1 
ATOM   795  N N     . ARG A 1 102 ? 26.68200  -24.52280 28.20971  1.000 9.31445   ? 1108 ARG A N     1 
ATOM   796  C CA    . ARG A 1 102 ? 25.70625  -25.20623 29.04286  1.000 10.40049  ? 1108 ARG A CA    1 
ATOM   797  C C     . ARG A 1 102 ? 24.26588  -24.83654 28.75711  1.000 10.05341  ? 1108 ARG A C     1 
ATOM   798  O O     . ARG A 1 102 ? 23.37346  -25.50983 29.28047  1.000 11.51991  ? 1108 ARG A O     1 
ATOM   799  C CB    . ARG A 1 102 ? 25.96334  -24.90295 30.51984  1.000 12.44047  ? 1108 ARG A CB    1 
ATOM   800  C CG    . ARG A 1 102 ? 27.30755  -25.38588 31.00249  1.000 14.33246  ? 1108 ARG A CG    1 
ATOM   801  C CD    . ARG A 1 102 ? 27.44514  -25.28231 32.49852  1.000 15.82207  ? 1108 ARG A CD    1 
ATOM   802  N NE    . ARG A 1 102 ? 26.79835  -26.41668 33.13731  1.000 17.67988  ? 1108 ARG A NE    1 
ATOM   803  C CZ    . ARG A 1 102 ? 25.61211  -26.36880 33.72907  1.000 19.20402  ? 1108 ARG A CZ    1 
ATOM   804  N NH1   . ARG A 1 102 ? 24.89185  -25.25694 33.75120  1.000 21.87768  ? 1108 ARG A NH1   1 
ATOM   805  N NH2   . ARG A 1 102 ? 25.13537  -27.46495 34.31326  1.000 19.54835  ? 1108 ARG A NH2   1 
ATOM   806  N N     . THR A 1 103 ? 24.01063  -23.76307 28.00798  1.000 9.64330   ? 1109 THR A N     1 
ATOM   807  C CA    . THR A 1 103 ? 22.65117  -23.30826 27.77723  1.000 9.46547   ? 1109 THR A CA    1 
ATOM   808  C C     . THR A 1 103 ? 22.40665  -23.10051 26.29560  1.000 9.02766   ? 1109 THR A C     1 
ATOM   809  O O     . THR A 1 103 ? 23.33375  -22.81720 25.52109  1.000 9.01521   ? 1109 THR A O     1 
ATOM   810  C CB    . THR A 1 103 ? 22.26657  -22.01483 28.53962  1.000 10.53514  ? 1109 THR A CB    1 
ATOM   811  O OG1   . THR A 1 103 ? 22.73617  -20.84785 27.85586  1.000 10.54214  ? 1109 THR A OG1   1 
ATOM   812  C CG2   . THR A 1 103 ? 22.77569  -22.02739 29.96605  1.000 11.82896  ? 1109 THR A CG2   1 
ATOM   813  N N     . GLY A 1 104 ? 21.13199  -23.23822 25.92581  1.000 8.97201   ? 1110 GLY A N     1 
ATOM   814  C CA    . GLY A 1 104 ? 20.67190  -22.84818 24.61693  1.000 9.37680   ? 1110 GLY A CA    1 
ATOM   815  C C     . GLY A 1 104 ? 19.41478  -22.01476 24.76174  1.000 8.80647   ? 1110 GLY A C     1 
ATOM   816  O O     . GLY A 1 104 ? 18.76458  -22.01848 25.80848  1.000 10.58209  ? 1110 GLY A O     1 
ATOM   817  N N     . SER A 1 105 ? 19.08649  -21.28234 23.70236  1.000 8.37443   ? 1111 SER A N     1 
ATOM   818  C CA    . SER A 1 105 ? 17.97785  -20.34702 23.75898  1.000 9.22409   ? 1111 SER A CA    1 
ATOM   819  C C     . SER A 1 105 ? 17.02713  -20.55155 22.59962  1.000 9.17486   ? 1111 SER A C     1 
ATOM   820  O O     . SER A 1 105 ? 17.44068  -20.91744 21.49543  1.000 9.45915   ? 1111 SER A O     1 
ATOM   821  C CB    . SER A 1 105 ? 18.46289  -18.91373 23.75252  1.000 9.46927   ? 1111 SER A CB    1 
ATOM   822  O OG    . SER A 1 105 ? 19.33950  -18.71712 24.84618  1.000 9.69475   ? 1111 SER A OG    1 
ATOM   823  N N     . LEU A 1 106 ? 15.75320  -20.25946 22.86589  1.000 9.02844   ? 1112 LEU A N     1 
ATOM   824  C CA    . LEU A 1 106 ? 14.69593  -20.31865 21.87432  1.000 9.31667   ? 1112 LEU A CA    1 
ATOM   825  C C     . LEU A 1 106 ? 14.02491  -18.95783 21.76493  1.000 9.42411   ? 1112 LEU A C     1 
ATOM   826  O O     . LEU A 1 106 ? 14.01352  -18.17073 22.72001  1.000 10.07565  ? 1112 LEU A O     1 
ATOM   827  C CB    . LEU A 1 106 ? 13.63286  -21.35523 22.26814  1.000 9.57453   ? 1112 LEU A CB    1 
ATOM   828  C CG    . LEU A 1 106 ? 14.15386  -22.75460 22.58657  1.000 10.39643  ? 1112 LEU A CG    1 
ATOM   829  C CD1   . LEU A 1 106 ? 13.00461  -23.66352 22.97250  1.000 11.08833  ? 1112 LEU A CD1   1 
ATOM   830  C CD2   . LEU A 1 106 ? 14.93765  -23.33679 21.41545  1.000 10.70847  ? 1112 LEU A CD2   1 
ATOM   831  N N     . CYS A 1 107 ? 13.44275  -18.70748 20.59183  1.000 9.22252   ? 1113 CYS A N     1 
ATOM   832  C CA    . CYS A 1 107 ? 12.73103  -17.47432 20.26629  1.000 9.79493   ? 1113 CYS A CA    1 
ATOM   833  C C     . CYS A 1 107 ? 11.31267  -17.90474 19.88241  1.000 9.84594   ? 1113 CYS A C     1 
ATOM   834  O O     . CYS A 1 107 ? 11.09883  -18.44446 18.78988  1.000 10.28597  ? 1113 CYS A O     1 
ATOM   835  C CB    . CYS A 1 107 ? 13.43937  -16.77564 19.10529  1.000 10.19456  ? 1113 CYS A CB    1 
ATOM   836  S SG    . CYS A 1 107 ? 12.65041  -15.26073 18.57741  1.000 10.58529  ? 1113 CYS A SG    1 
ATOM   837  N N     . VAL A 1 108 ? 10.35724  -17.70645 20.79703  1.000 10.31874  ? 1114 VAL A N     1 
ATOM   838  C CA    . VAL A 1 108 ? 9.07589   -18.40450 20.75267  1.000 10.15008  ? 1114 VAL A CA    1 
ATOM   839  C C     . VAL A 1 108 ? 7.93683   -17.39947 20.66271  1.000 10.69697  ? 1114 VAL A C     1 
ATOM   840  O O     . VAL A 1 108 ? 7.76488   -16.56110 21.55782  1.000 11.33072  ? 1114 VAL A O     1 
ATOM   841  C CB    . VAL A 1 108 ? 8.89260   -19.30770 21.98295  1.000 10.61416  ? 1114 VAL A CB    1 
ATOM   842  C CG1   . VAL A 1 108 ? 7.51273   -19.96170 21.96673  1.000 11.51698  ? 1114 VAL A CG1   1 
ATOM   843  C CG2   . VAL A 1 108 ? 9.98171   -20.35608 22.03369  1.000 11.24317  ? 1114 VAL A CG2   1 
ATOM   844  N N     . ARG A 1 109 ? 7.14186   -17.50823 19.60312  1.000 11.26387  ? 1115 ARG A N     1 
ATOM   845  C CA    . ARG A 1 109 ? 5.92672   -16.71858 19.47873  1.000 11.92853  ? 1115 ARG A CA    1 
ATOM   846  C C     . ARG A 1 109 ? 4.79107   -17.39868 20.24263  1.000 11.50885  ? 1115 ARG A C     1 
ATOM   847  O O     . ARG A 1 109 ? 4.50373   -18.57809 20.01932  1.000 12.71697  ? 1115 ARG A O     1 
ATOM   848  C CB    . ARG A 1 109 ? 5.56096   -16.59950 18.00120  1.000 12.43828  ? 1115 ARG A CB    1 
ATOM   849  C CG    . ARG A 1 109 ? 4.25039   -15.89149 17.72997  1.000 15.18381  ? 1115 ARG A CG    1 
ATOM   850  C CD    . ARG A 1 109 ? 4.30954   -14.43902 18.18961  1.000 32.61251  ? 1115 ARG A CD    1 
ATOM   851  N NE    . ARG A 1 109 ? 3.00421   -13.78908 18.15364  1.000 117.80787 ? 1115 ARG A NE    1 
ATOM   852  C CZ    . ARG A 1 109 ? 2.50241   -13.16882 17.09435  1.000 94.87649  ? 1115 ARG A CZ    1 
ATOM   853  N NH1   . ARG A 1 109 ? 3.19768   -13.03763 15.97589  1.000 49.45120  ? 1115 ARG A NH1   1 
ATOM   854  N NH2   . ARG A 1 109 ? 1.27672   -12.65666 17.16301  1.000 44.88969  ? 1115 ARG A NH2   1 
ATOM   855  N N     . ARG A 1 110 ? 4.13348   -16.66111 21.13459  1.000 12.54620  ? 1116 ARG A N     1 
ATOM   856  C CA    . ARG A 1 110 ? 3.01124   -17.23322 21.86526  1.000 13.38813  ? 1116 ARG A CA    1 
ATOM   857  C C     . ARG A 1 110 ? 1.81768   -17.35262 20.92096  1.000 13.65654  ? 1116 ARG A C     1 
ATOM   858  O O     . ARG A 1 110 ? 1.34815   -16.34577 20.38123  1.000 15.51056  ? 1116 ARG A O     1 
ATOM   859  C CB    . ARG A 1 110 ? 2.66769   -16.33197 23.04753  1.000 15.40292  ? 1116 ARG A CB    1 
ATOM   860  C CG    . ARG A 1 110 ? 1.67959   -16.93563 24.02977  1.000 15.46051  ? 1116 ARG A CG    1 
ATOM   861  C CD    . ARG A 1 110 ? 1.20736   -15.90178 25.03368  1.000 16.19130  ? 1116 ARG A CD    1 
ATOM   862  N NE    . ARG A 1 110 ? 2.18797   -15.58023 26.07109  1.000 16.62445  ? 1116 ARG A NE    1 
ATOM   863  C CZ    . ARG A 1 110 ? 2.32769   -16.25627 27.20500  1.000 15.60225  ? 1116 ARG A CZ    1 
ATOM   864  N NH1   . ARG A 1 110 ? 1.67950   -17.38776 27.40966  1.000 15.83784  ? 1116 ARG A NH1   1 
ATOM   865  N NH2   . ARG A 1 110 ? 3.13291   -15.78153 28.15602  1.000 15.46012  ? 1116 ARG A NH2   1 
ATOM   866  N N     . ALA A 1 111 ? 1.31079   -18.57216 20.72306  1.000 13.20332  ? 1117 ALA A N     1 
ATOM   867  C CA    . ALA A 1 111 ? 0.16715   -18.80742 19.84359  1.000 14.42623  ? 1117 ALA A CA    1 
ATOM   868  C C     . ALA A 1 111 ? -1.11352  -18.69580 20.66530  1.000 14.97866  ? 1117 ALA A C     1 
ATOM   869  O O     . ALA A 1 111 ? -1.42041  -19.57871 21.47793  1.000 15.47024  ? 1117 ALA A O     1 
ATOM   870  C CB    . ALA A 1 111 ? 0.28509   -20.17725 19.18336  1.000 15.05956  ? 1117 ALA A CB    1 
ATOM   871  N N     . VAL A 1 112 ? -1.86535  -17.61467 20.45381  1.000 16.52988  ? 1118 VAL A N     1 
ATOM   872  C CA    . VAL A 1 112 ? -3.08543  -17.33229 21.19942  1.000 17.60014  ? 1118 VAL A CA    1 
ATOM   873  C C     . VAL A 1 112 ? -4.25726  -17.32244 20.23245  1.000 19.33946  ? 1118 VAL A C     1 
ATOM   874  O O     . VAL A 1 112 ? -4.18494  -16.72140 19.15567  1.000 21.08718  ? 1118 VAL A O     1 
ATOM   875  C CB    . VAL A 1 112 ? -3.00080  -15.99777 21.96772  1.000 19.49244  ? 1118 VAL A CB    1 
ATOM   876  C CG1   . VAL A 1 112 ? -4.24659  -15.79628 22.80607  1.000 21.21955  ? 1118 VAL A CG1   1 
ATOM   877  C CG2   . VAL A 1 112 ? -1.77661  -15.97768 22.85408  1.000 20.29761  ? 1118 VAL A CG2   1 
ATOM   878  N N     . TYR A 1 113 ? -5.33807  -17.98642 20.61971  1.000 19.95906  ? 1119 TYR A N     1 
ATOM   879  C CA    . TYR A 1 113 ? -6.52860  -18.04468 19.78770  1.000 20.57350  ? 1119 TYR A CA    1 
ATOM   880  C C     . TYR A 1 113 ? -7.47406  -16.90031 20.11321  1.000 19.77956  ? 1119 TYR A C     1 
ATOM   881  O O     . TYR A 1 113 ? -7.75692  -16.62228 21.28244  1.000 19.02375  ? 1119 TYR A O     1 
ATOM   882  C CB    . TYR A 1 113 ? -7.27518  -19.35583 20.00269  1.000 21.73012  ? 1119 TYR A CB    1 
ATOM   883  C CG    . TYR A 1 113 ? -8.57409  -19.41091 19.23620  1.000 22.11614  ? 1119 TYR A CG    1 
ATOM   884  C CD1   . TYR A 1 113 ? -8.59658  -19.84740 17.92198  1.000 23.01777  ? 1119 TYR A CD1   1 
ATOM   885  C CD2   . TYR A 1 113 ? -9.77240  -19.00849 19.81589  1.000 23.35726  ? 1119 TYR A CD2   1 
ATOM   886  C CE1   . TYR A 1 113 ? -9.76632  -19.89345 17.21045  1.000 24.09189  ? 1119 TYR A CE1   1 
ATOM   887  C CE2   . TYR A 1 113 ? -10.95534 -19.04858 19.10576  1.000 24.06424  ? 1119 TYR A CE2   1 
ATOM   888  C CZ    . TYR A 1 113 ? -10.94144 -19.49161 17.80559  1.000 24.08313  ? 1119 TYR A CZ    1 
ATOM   889  O OH    . TYR A 1 113 ? -12.11393 -19.53580 17.09920  1.000 25.12892  ? 1119 TYR A OH    1 
ATOM   890  N N     . TYR A 1 114 ? -7.99392  -16.27174 19.06251  1.000 20.66215  ? 1120 TYR A N     1 
ATOM   891  C CA    . TYR A 1 114 ? -9.06938  -15.29290 19.16919  1.000 21.06341  ? 1120 TYR A CA    1 
ATOM   892  C C     . TYR A 1 114 ? -10.17474 -15.68484 18.20568  1.000 20.27244  ? 1120 TYR A C     1 
ATOM   893  O O     . TYR A 1 114 ? -9.89706  -16.02484 17.05166  1.000 20.35907  ? 1120 TYR A O     1 
ATOM   894  C CB    . TYR A 1 114 ? -8.56150  -13.89696 18.80469  1.000 22.88897  ? 1120 TYR A CB    1 
ATOM   895  C CG    . TYR A 1 114 ? -7.36314  -13.49525 19.61261  1.000 24.74799  ? 1120 TYR A CG    1 
ATOM   896  C CD1   . TYR A 1 114 ? -7.50970  -13.02349 20.90728  1.000 25.89541  ? 1120 TYR A CD1   1 
ATOM   897  C CD2   . TYR A 1 114 ? -6.07690  -13.62326 19.09866  1.000 25.15728  ? 1120 TYR A CD2   1 
ATOM   898  C CE1   . TYR A 1 114 ? -6.41228  -12.66381 21.66168  1.000 26.43054  ? 1120 TYR A CE1   1 
ATOM   899  C CE2   . TYR A 1 114 ? -4.97064  -13.27078 19.84604  1.000 26.22041  ? 1120 TYR A CE2   1 
ATOM   900  C CZ    . TYR A 1 114 ? -5.14304  -12.79376 21.12693  1.000 26.12265  ? 1120 TYR A CZ    1 
ATOM   901  O OH    . TYR A 1 114 ? -4.03376  -12.44591 21.86632  1.000 27.80759  ? 1120 TYR A OH    1 
ATOM   902  N N     . ASP A 1 115 ? -11.41762 -15.63996 18.66775  1.000 19.51747  ? 1121 ASP A N     1 
ATOM   903  C CA    . ASP A 1 115 ? -12.52443 -15.90442 17.76507  1.000 18.61805  ? 1121 ASP A CA    1 
ATOM   904  C C     . ASP A 1 115 ? -12.45971 -14.86226 16.65271  1.000 19.73520  ? 1121 ASP A C     1 
ATOM   905  O O     . ASP A 1 115 ? -12.24418 -13.67474 16.93942  1.000 20.96567  ? 1121 ASP A O     1 
ATOM   906  C CB    . ASP A 1 115 ? -13.85372 -15.73103 18.48164  1.000 17.29007  ? 1121 ASP A CB    1 
ATOM   907  C CG    . ASP A 1 115 ? -15.01905 -15.92046 17.54571  1.000 16.39855  ? 1121 ASP A CG    1 
ATOM   908  O OD1   . ASP A 1 115 ? -15.31863 -17.08542 17.20265  1.000 16.14443  ? 1121 ASP A OD1   1 
ATOM   909  O OD2   . ASP A 1 115 ? -15.54615 -14.91107 17.04934  1.000 16.33401  ? 1121 ASP A OD2   1 
ATOM   910  N N     . PRO A 1 116 ? -12.60576 -15.25437 15.38363  1.000 21.28105  ? 1122 PRO A N     1 
ATOM   911  C CA    . PRO A 1 116 ? -12.41938 -14.27735 14.29613  1.000 23.41185  ? 1122 PRO A CA    1 
ATOM   912  C C     . PRO A 1 116 ? -13.42303 -13.13521 14.29944  1.000 23.99978  ? 1122 PRO A C     1 
ATOM   913  O O     . PRO A 1 116 ? -13.12584 -12.06947 13.74336  1.000 26.00592  ? 1122 PRO A O     1 
ATOM   914  C CB    . PRO A 1 116 ? -12.53632 -15.12068 13.01916  1.000 25.30466  ? 1122 PRO A CB    1 
ATOM   915  C CG    . PRO A 1 116 ? -12.34776 -16.52823 13.43662  1.000 24.68816  ? 1122 PRO A CG    1 
ATOM   916  C CD    . PRO A 1 116 ? -12.61512 -16.64776 14.90620  1.000 21.94848  ? 1122 PRO A CD    1 
ATOM   917  N N     A GLU A 1 117 ? -14.58256 -13.30549 14.93235  0.508 23.78473  ? 1123 GLU A N     1 
ATOM   918  N N     B GLU A 1 117 ? -14.61584 -13.33050 14.86272  0.492 24.57625  ? 1123 GLU A N     1 
ATOM   919  C CA    A GLU A 1 117 ? -15.60835 -12.27137 14.94612  0.508 23.70142  ? 1123 GLU A CA    1 
ATOM   920  C CA    B GLU A 1 117 ? -15.64519 -12.28248 14.84346  0.492 25.70032  ? 1123 GLU A CA    1 
ATOM   921  C C     A GLU A 1 117 ? -15.68541 -11.50229 16.25768  0.508 20.91966  ? 1123 GLU A C     1 
ATOM   922  C C     B GLU A 1 117 ? -15.56451 -11.40035 16.08526  0.492 25.46330  ? 1123 GLU A C     1 
ATOM   923  O O     A GLU A 1 117 ? -15.97274 -10.30008 16.23852  0.508 22.49759  ? 1123 GLU A O     1 
ATOM   924  O O     B GLU A 1 117 ? -15.19135 -10.22720 16.00041  0.492 25.20553  ? 1123 GLU A O     1 
ATOM   925  C CB    A GLU A 1 117 ? -16.97863 -12.88342 14.63660  0.508 25.67342  ? 1123 GLU A CB    1 
ATOM   926  C CB    B GLU A 1 117 ? -17.04373 -12.88114 14.67723  0.492 26.31425  ? 1123 GLU A CB    1 
ATOM   927  C CG    A GLU A 1 117 ? -17.08810 -13.46886 13.23587  0.508 27.45506  ? 1123 GLU A CG    1 
ATOM   928  C CG    B GLU A 1 117 ? -18.15468 -11.86979 14.95146  0.492 27.01531  ? 1123 GLU A CG    1 
ATOM   929  C CD    A GLU A 1 117 ? -17.57573 -12.45935 12.21579  0.508 29.11409  ? 1123 GLU A CD    1 
ATOM   930  C CD    B GLU A 1 117 ? -19.38651 -12.07817 14.09891  0.492 27.39928  ? 1123 GLU A CD    1 
ATOM   931  O OE1   A GLU A 1 117 ? -17.90188 -11.32124 12.61439  0.508 29.77303  ? 1123 GLU A OE1   1 
ATOM   932  O OE1   B GLU A 1 117 ? -19.24717 -12.45679 12.91774  0.492 27.70725  ? 1123 GLU A OE1   1 
ATOM   933  O OE2   A GLU A 1 117 ? -17.63709 -12.80465 11.01583  0.508 29.30008  ? 1123 GLU A OE2   1 
ATOM   934  O OE2   B GLU A 1 117 ? -20.49955 -11.85596 14.61710  0.492 28.03775  ? 1123 GLU A OE2   1 
ATOM   935  N N     A THR A 1 118 ? -15.44189 -12.15582 17.39506  0.508 18.39347  ? 1124 THR A N     1 
ATOM   936  N N     B THR A 1 118 ? -15.92535 -11.95525 17.24450  0.492 26.17175  ? 1124 THR A N     1 
ATOM   937  C CA    A THR A 1 118 ? -15.55697 -11.49890 18.68807  0.508 16.55994  ? 1124 THR A CA    1 
ATOM   938  C CA    B THR A 1 118 ? -15.99600 -11.15538 18.46063  0.492 25.70958  ? 1124 THR A CA    1 
ATOM   939  C C     A THR A 1 118 ? -14.22623 -11.27958 19.38779  0.508 15.13674  ? 1124 THR A C     1 
ATOM   940  C C     B THR A 1 118 ? -14.64173 -10.59042 18.85763  0.492 26.15895  ? 1124 THR A C     1 
ATOM   941  O O     A THR A 1 118 ? -14.17341 -10.49242 20.33849  0.508 15.96822  ? 1124 THR A O     1 
ATOM   942  O O     B THR A 1 118 ? -14.58682 -9.61142  19.60980  0.492 26.98880  ? 1124 THR A O     1 
ATOM   943  C CB    A THR A 1 118 ? -16.45855 -12.31820 19.62300  0.508 16.53824  ? 1124 THR A CB    1 
ATOM   944  C CB    B THR A 1 118 ? -16.53628 -12.00450 19.61284  0.492 24.09593  ? 1124 THR A CB    1 
ATOM   945  O OG1   A THR A 1 118 ? -15.77767 -13.52625 19.98336  0.508 15.60915  ? 1124 THR A OG1   1 
ATOM   946  O OG1   B THR A 1 118 ? -15.70780 -13.16378 19.77865  0.492 22.57989  ? 1124 THR A OG1   1 
ATOM   947  C CG2   A THR A 1 118 ? -17.78425 -12.65350 18.94920  0.508 16.73121  ? 1124 THR A CG2   1 
ATOM   948  C CG2   B THR A 1 118 ? -17.97001 -12.44022 19.33412  0.492 23.77965  ? 1124 THR A CG2   1 
ATOM   949  N N     A GLY A 1 119 ? -13.16269 -11.95688 18.95811  0.508 13.66664  ? 1125 GLY A N     1 
ATOM   950  N N     B GLY A 1 119 ? -13.55247 -11.17486 18.36479  0.492 25.21278  ? 1125 GLY A N     1 
ATOM   951  C CA    A GLY A 1 119 ? -11.89562 -11.88538 19.64840  0.508 12.95914  ? 1125 GLY A CA    1 
ATOM   952  C CA    B GLY A 1 119 ? -12.23889 -10.85262 18.86812  0.492 25.34631  ? 1125 GLY A CA    1 
ATOM   953  C C     A GLY A 1 119 ? -11.82321 -12.67374 20.93423  0.508 13.25990  ? 1125 GLY A C     1 
ATOM   954  C C     B GLY A 1 119 ? -11.95300 -11.38432 20.25184  0.492 25.60927  ? 1125 GLY A C     1 
ATOM   955  O O     A GLY A 1 119 ? -10.78507 -12.62949 21.59986  0.508 13.95303  ? 1125 GLY A O     1 
ATOM   956  O O     B GLY A 1 119 ? -10.87362 -11.11179 20.78894  0.492 25.43797  ? 1125 GLY A O     1 
ATOM   957  N N     A LYS A 1 120 ? -12.88189 -13.39741 21.30218  0.508 12.52274  ? 1126 LYS A N     1 
ATOM   958  N N     B LYS A 1 120 ? -12.88171 -12.13252 20.84531  0.492 26.40384  ? 1126 LYS A N     1 
ATOM   959  C CA    A LYS A 1 120 ? -12.89780 -14.10573 22.57520  0.508 12.87290  ? 1126 LYS A CA    1 
ATOM   960  C CA    B LYS A 1 120 ? -12.67725 -12.66702 22.18291  0.492 26.93647  ? 1126 LYS A CA    1 
ATOM   961  C C     A LYS A 1 120 ? -11.84493 -15.20722 22.60289  0.508 11.52845  ? 1126 LYS A C     1 
ATOM   962  C C     B LYS A 1 120 ? -11.57615 -13.71631 22.17563  0.492 25.78787  ? 1126 LYS A C     1 
ATOM   963  O O     A LYS A 1 120 ? -11.68877 -15.97596 21.64852  0.508 11.66555  ? 1126 LYS A O     1 
ATOM   964  O O     B LYS A 1 120 ? -11.52851 -14.58948 21.30435  0.492 24.70501  ? 1126 LYS A O     1 
ATOM   965  C CB    A LYS A 1 120 ? -14.28219 -14.70714 22.83454  0.508 14.95837  ? 1126 LYS A CB    1 
ATOM   966  C CB    B LYS A 1 120 ? -13.96658 -13.29401 22.71478  0.492 28.32245  ? 1126 LYS A CB    1 
ATOM   967  C CG    A LYS A 1 120 ? -15.33733 -13.71637 23.30841  0.508 18.30052  ? 1126 LYS A CG    1 
ATOM   968  C CG    B LYS A 1 120 ? -15.02331 -12.29613 23.15620  0.492 29.78909  ? 1126 LYS A CG    1 
ATOM   969  C CD    A LYS A 1 120 ? -16.65055 -14.43653 23.62177  0.508 20.54356  ? 1126 LYS A CD    1 
ATOM   970  C CD    B LYS A 1 120 ? -16.40026 -12.93874 23.21495  0.492 31.26027  ? 1126 LYS A CD    1 
ATOM   971  C CE    A LYS A 1 120 ? -17.84350 -13.48335 23.67535  0.508 22.28713  ? 1126 LYS A CE    1 
ATOM   972  C CE    B LYS A 1 120 ? -17.28174 -12.24951 24.24368  0.492 32.14763  ? 1126 LYS A CE    1 
ATOM   973  N NZ    A LYS A 1 120 ? -19.11520 -14.16638 24.09534  0.508 22.99347  ? 1126 LYS A NZ    1 
ATOM   974  N NZ    B LYS A 1 120 ? -18.71113 -12.64737 24.10851  0.492 32.83025  ? 1126 LYS A NZ    1 
ATOM   975  N N     A GLU A 1 121 ? -11.13977 -15.29227 23.72272  0.508 11.64132  ? 1127 GLU A N     1 
ATOM   976  N N     B GLU A 1 121 ? -10.69404 -13.62741 23.16468  0.492 26.14125  ? 1127 GLU A N     1 
ATOM   977  C CA    A GLU A 1 121 ? -10.11477 -16.29856 23.90455  0.508 11.86569  ? 1127 GLU A CA    1 
ATOM   978  C CA    B GLU A 1 121 ? -9.60992  -14.58383 23.31512  0.492 26.67643  ? 1127 GLU A CA    1 
ATOM   979  C C     A GLU A 1 121 ? -10.75232 -17.63736 24.26853  0.508 10.74478  ? 1127 GLU A C     1 
ATOM   980  C C     B GLU A 1 121 ? -10.14852 -15.85083 23.96544  0.492 23.21331  ? 1127 GLU A C     1 
ATOM   981  O O     A GLU A 1 121 ? -11.94499 -17.73296 24.56546  0.508 10.95144  ? 1127 GLU A O     1 
ATOM   982  O O     B GLU A 1 121 ? -10.91342 -15.78355 24.93284  0.492 23.63458  ? 1127 GLU A O     1 
ATOM   983  C CB    A GLU A 1 121 ? -9.14347  -15.83383 24.98612  0.508 13.48440  ? 1127 GLU A CB    1 
ATOM   984  C CB    B GLU A 1 121 ? -8.51641  -13.96714 24.18684  0.492 30.62511  ? 1127 GLU A CB    1 
ATOM   985  C CG    A GLU A 1 121 ? -8.45926  -14.52172 24.59693  0.508 16.04157  ? 1127 GLU A CG    1 
ATOM   986  C CG    B GLU A 1 121 ? -7.22969  -14.76664 24.26461  0.492 34.10436  ? 1127 GLU A CG    1 
ATOM   987  C CD    A GLU A 1 121 ? -7.30343  -14.12806 25.49816  0.508 20.26167  ? 1127 GLU A CD    1 
ATOM   988  C CD    B GLU A 1 121 ? -7.03585  -15.47412 25.58865  0.492 36.94407  ? 1127 GLU A CD    1 
ATOM   989  O OE1   A GLU A 1 121 ? -6.56222  -15.02260 25.95574  0.508 22.60984  ? 1127 GLU A OE1   1 
ATOM   990  O OE1   B GLU A 1 121 ? -7.60352  -15.01401 26.60435  0.492 37.92194  ? 1127 GLU A OE1   1 
ATOM   991  O OE2   A GLU A 1 121 ? -7.12590  -12.91159 25.73444  0.508 20.84267  ? 1127 GLU A OE2   1 
ATOM   992  O OE2   B GLU A 1 121 ? -6.28958  -16.47790 25.61353  0.492 37.78979  ? 1127 GLU A OE2   1 
ATOM   993  N N     A ASP A 1 122 ? -9.94421  -18.68156 24.22076  0.508 10.45119  ? 1128 ASP A N     1 
ATOM   994  N N     B ASP A 1 122 ? -9.76883  -17.00397 23.42184  0.492 19.61317  ? 1128 ASP A N     1 
ATOM   995  C CA    A ASP A 1 122 ? -10.33811 -20.02078 24.63058  0.508 9.86132   ? 1128 ASP A CA    1 
ATOM   996  C CA    B ASP A 1 122 ? -10.14171 -18.29872 23.99410  0.492 17.74270  ? 1128 ASP A CA    1 
ATOM   997  C C     A ASP A 1 122 ? -9.06153  -20.75487 24.99708  0.508 9.32189   ? 1128 ASP A C     1 
ATOM   998  C C     B ASP A 1 122 ? -8.86924  -19.03572 24.38297  0.492 16.53807  ? 1128 ASP A C     1 
ATOM   999  O O     A ASP A 1 122 ? -8.27144  -21.09931 24.10917  0.508 10.14948  ? 1128 ASP A O     1 
ATOM   1000 O O     B ASP A 1 122 ? -8.23306  -19.67632 23.52637  0.492 15.34984  ? 1128 ASP A O     1 
ATOM   1001 C CB    A ASP A 1 122 ? -11.03939 -20.75046 23.48678  0.508 10.02243  ? 1128 ASP A CB    1 
ATOM   1002 C CB    B ASP A 1 122 ? -10.95347 -19.12012 22.99484  0.492 16.69253  ? 1128 ASP A CB    1 
ATOM   1003 C CG    A ASP A 1 122 ? -11.52453 -22.13235 23.87899  0.508 10.20137  ? 1128 ASP A CG    1 
ATOM   1004 C CG    B ASP A 1 122 ? -11.50552 -20.40309 23.59249  0.492 15.09523  ? 1128 ASP A CG    1 
ATOM   1005 O OD1   A ASP A 1 122 ? -11.05559 -22.71306 24.88539  0.508 9.95031   ? 1128 ASP A OD1   1 
ATOM   1006 O OD1   B ASP A 1 122 ? -11.06747 -20.80120 24.69520  0.492 15.23944  ? 1128 ASP A OD1   1 
ATOM   1007 O OD2   A ASP A 1 122 ? -12.44933 -22.63665 23.20136  0.508 10.57865  ? 1128 ASP A OD2   1 
ATOM   1008 O OD2   B ASP A 1 122 ? -12.38465 -21.01470 22.95039  0.492 15.12138  ? 1128 ASP A OD2   1 
ATOM   1009 N N     A PRO A 1 123 ? -8.81430  -21.00665 26.28157  0.508 9.28608   ? 1129 PRO A N     1 
ATOM   1010 N N     B PRO A 1 123 ? -8.46651  -18.98514 25.65594  0.492 16.58310  ? 1129 PRO A N     1 
ATOM   1011 C CA    A PRO A 1 123 ? -7.54118  -21.64068 26.66002  0.508 9.60551   ? 1129 PRO A CA    1 
ATOM   1012 C CA    B PRO A 1 123 ? -7.22506  -19.66316 26.06512  0.492 15.81852  ? 1129 PRO A CA    1 
ATOM   1013 C C     A PRO A 1 123 ? -7.33818  -23.00795 26.03431  0.508 9.75861   ? 1129 PRO A C     1 
ATOM   1014 C C     B PRO A 1 123 ? -7.21788  -21.15777 25.79694  0.492 14.83762  ? 1129 PRO A C     1 
ATOM   1015 O O     A PRO A 1 123 ? -6.18999  -23.42471 25.83007  0.508 10.46337  ? 1129 PRO A O     1 
ATOM   1016 O O     B PRO A 1 123 ? -6.13747  -21.73842 25.63499  0.492 14.57716  ? 1129 PRO A O     1 
ATOM   1017 C CB    A PRO A 1 123 ? -7.62728  -21.71556 28.18948  0.508 10.40672  ? 1129 PRO A CB    1 
ATOM   1018 C CB    B PRO A 1 123 ? -7.12767  -19.34676 27.56587  0.492 17.27227  ? 1129 PRO A CB    1 
ATOM   1019 C CG    A PRO A 1 123 ? -9.10516  -21.66982 28.47493  0.508 11.81431  ? 1129 PRO A CG    1 
ATOM   1020 C CG    B PRO A 1 123 ? -7.93011  -18.09741 27.73985  0.492 18.16855  ? 1129 PRO A CG    1 
ATOM   1021 C CD    A PRO A 1 123 ? -9.68603  -20.76709 27.44141  0.508 9.95267   ? 1129 PRO A CD    1 
ATOM   1022 C CD    B PRO A 1 123 ? -9.05595  -18.19997 26.75243  0.492 17.52987  ? 1129 PRO A CD    1 
ATOM   1023 N N     A SER A 1 124 ? -8.41768  -23.72012 25.71464  0.508 10.61565  ? 1130 SER A N     1 
ATOM   1024 N N     B SER A 1 124 ? -8.38540  -21.80360 25.73780  0.492 14.20511  ? 1130 SER A N     1 
ATOM   1025 C CA    A SER A 1 124 ? -8.28661  -25.05300 25.13974  0.508 11.28443  ? 1130 SER A CA    1 
ATOM   1026 C CA    B SER A 1 124 ? -8.41836  -23.23905 25.48108  0.492 13.49746  ? 1130 SER A CA    1 
ATOM   1027 C C     A SER A 1 124 ? -7.77629  -25.03108 23.70738  0.508 10.62799  ? 1130 SER A C     1 
ATOM   1028 C C     B SER A 1 124 ? -7.94012  -23.59186 24.08072  0.492 13.77362  ? 1130 SER A C     1 
ATOM   1029 O O     A SER A 1 124 ? -7.35321  -26.07373 23.20329  0.508 12.02978  ? 1130 SER A O     1 
ATOM   1030 O O     B SER A 1 124 ? -7.56581  -24.74541 23.84046  0.492 14.96657  ? 1130 SER A O     1 
ATOM   1031 C CB    A SER A 1 124 ? -9.62020  -25.79969 25.22178  0.508 11.83541  ? 1130 SER A CB    1 
ATOM   1032 C CB    B SER A 1 124 ? -9.82368  -23.79657 25.69892  0.492 13.58992  ? 1130 SER A CB    1 
ATOM   1033 O OG    A SER A 1 124 ? -10.53421 -25.35768 24.23059  0.508 14.63527  ? 1130 SER A OG    1 
ATOM   1034 O OG    B SER A 1 124 ? -10.66694 -23.52515 24.59156  0.492 13.79341  ? 1130 SER A OG    1 
ATOM   1035 N N     A LYS A 1 125 ? -7.80247  -23.87688 23.04836  0.508 10.13079  ? 1131 LYS A N     1 
ATOM   1036 N N     B LYS A 1 125 ? -7.94267  -22.63500 23.15568  0.492 13.54818  ? 1131 LYS A N     1 
ATOM   1037 C CA    A LYS A 1 125 ? -7.36026  -23.74738 21.66713  0.508 11.36193  ? 1131 LYS A CA    1 
ATOM   1038 C CA    B LYS A 1 125 ? -7.45996  -22.86437 21.80213  0.492 13.84881  ? 1131 LYS A CA    1 
ATOM   1039 C C     A LYS A 1 125 ? -6.01923  -23.03815 21.53669  0.508 11.24180  ? 1131 LYS A C     1 
ATOM   1040 C C     B LYS A 1 125 ? -6.10789  -22.20989 21.54573  0.492 14.48812  ? 1131 LYS A C     1 
ATOM   1041 O O     A LYS A 1 125 ? -5.55715  -22.80949 20.41315  0.508 12.03650  ? 1131 LYS A O     1 
ATOM   1042 O O     B LYS A 1 125 ? -5.68804  -22.09838 20.38895  0.492 15.02253  ? 1131 LYS A O     1 
ATOM   1043 C CB    A LYS A 1 125 ? -8.43096  -23.03502 20.83672  0.508 12.63494  ? 1131 LYS A CB    1 
ATOM   1044 C CB    B LYS A 1 125 ? -8.50083  -22.40204 20.78554  0.492 14.31207  ? 1131 LYS A CB    1 
ATOM   1045 C CG    A LYS A 1 125 ? -9.73274  -23.81325 20.75476  0.508 12.87413  ? 1131 LYS A CG    1 
ATOM   1046 C CG    B LYS A 1 125 ? -9.83594  -23.09859 20.91431  0.492 15.34565  ? 1131 LYS A CG    1 
ATOM   1047 C CD    A LYS A 1 125 ? -10.78434 -23.05351 19.96364  0.508 13.33322  ? 1131 LYS A CD    1 
ATOM   1048 C CD    B LYS A 1 125 ? -10.85429 -22.50672 19.96277  0.492 16.08360  ? 1131 LYS A CD    1 
ATOM   1049 C CE    A LYS A 1 125 ? -12.09579 -23.82421 19.89331  0.508 13.86250  ? 1131 LYS A CE    1 
ATOM   1050 C CE    B LYS A 1 125 ? -12.12750 -23.33174 19.93934  0.492 16.49221  ? 1131 LYS A CE    1 
ATOM   1051 N NZ    A LYS A 1 125 ? -13.10073 -23.12797 19.04101  0.508 14.69818  ? 1131 LYS A NZ    1 
ATOM   1052 N NZ    B LYS A 1 125 ? -13.17363 -22.68592 19.10007  0.492 16.30189  ? 1131 LYS A NZ    1 
ATOM   1053 N N     A ASN A 1 126 ? -5.38314  -22.69388 22.65037  0.508 11.16658  ? 1132 ASN A N     1 
ATOM   1054 N N     B ASN A 1 126 ? -5.42335  -21.76573 22.59405  0.492 14.59806  ? 1132 ASN A N     1 
ATOM   1055 C CA    A ASN A 1 126 ? -4.06569  -22.08805 22.60326  0.508 12.09720  ? 1132 ASN A CA    1 
ATOM   1056 C CA    B ASN A 1 126 ? -4.08877  -21.22078 22.42870  0.492 14.20056  ? 1132 ASN A CA    1 
ATOM   1057 C C     A ASN A 1 126 ? -3.02578  -23.11983 22.19486  0.508 12.44380  ? 1132 ASN A C     1 
ATOM   1058 C C     B ASN A 1 126 ? -3.10143  -22.34875 22.13829  0.492 13.90343  ? 1132 ASN A C     1 
ATOM   1059 O O     A ASN A 1 126 ? -3.16741  -24.31940 22.45651  0.508 13.14141  ? 1132 ASN A O     1 
ATOM   1060 O O     B ASN A 1 126 ? -3.38968  -23.52890 22.34543  0.492 14.54184  ? 1132 ASN A O     1 
ATOM   1061 C CB    A ASN A 1 126 ? -3.69392  -21.53707 23.97394  0.508 12.16780  ? 1132 ASN A CB    1 
ATOM   1062 C CB    B ASN A 1 126 ? -3.67007  -20.46660 23.68973  0.492 15.68076  ? 1132 ASN A CB    1 
ATOM   1063 C CG    A ASN A 1 126 ? -4.42079  -20.26583 24.29794  0.508 12.02073  ? 1132 ASN A CG    1 
ATOM   1064 C CG    B ASN A 1 126 ? -4.39876  -19.14406 23.84507  0.492 18.09840  ? 1132 ASN A CG    1 
ATOM   1065 O OD1   A ASN A 1 126 ? -5.06173  -19.67579 23.43228  0.508 12.36696  ? 1132 ASN A OD1   1 
ATOM   1066 O OD1   B ASN A 1 126 ? -5.24657  -18.78715 23.02286  0.492 19.42142  ? 1132 ASN A OD1   1 
ATOM   1067 N ND2   A ASN A 1 126 ? -4.31297  -19.82000 25.54182  0.508 13.25669  ? 1132 ASN A ND2   1 
ATOM   1068 N ND2   B ASN A 1 126 ? -4.06984  -18.40780 24.90125  0.492 18.67743  ? 1132 ASN A ND2   1 
ATOM   1069 N N     A GLY A 1 127 ? -1.96242  -22.64143 21.55838  0.508 11.60233  ? 1133 GLY A N     1 
ATOM   1070 N N     B GLY A 1 127 ? -1.92740  -21.97778 21.63616  0.492 13.69053  ? 1133 GLY A N     1 
ATOM   1071 C CA    A GLY A 1 127 ? -0.84843  -23.51368 21.26212  0.508 11.18490  ? 1133 GLY A CA    1 
ATOM   1072 C CA    B GLY A 1 127 ? -0.91485  -22.97924 21.34235  0.492 14.33554  ? 1133 GLY A CA    1 
ATOM   1073 C C     A GLY A 1 127 ? -0.22051  -24.03946 22.53636  0.508 11.08081  ? 1133 GLY A C     1 
ATOM   1074 C C     B GLY A 1 127 ? -0.31288  -23.52986 22.62309  0.492 14.09592  ? 1133 GLY A C     1 
ATOM   1075 O O     A GLY A 1 127 ? 0.24251   -23.25438 23.37061  0.508 11.85771  ? 1133 GLY A O     1 
ATOM   1076 O O     B GLY A 1 127 ? 0.06191   -22.77063 23.52396  0.492 15.74833  ? 1133 GLY A O     1 
ATOM   1077 N N     A VAL A 1 128 ? -0.19228  -25.36613 22.69400  0.508 11.13235  ? 1134 VAL A N     1 
ATOM   1078 N N     B VAL A 1 128 ? -0.19567  -24.85720 22.70396  0.492 13.32298  ? 1134 VAL A N     1 
ATOM   1079 C CA    A VAL A 1 128 ? 0.22356   -25.96498 23.96186  0.508 12.10102  ? 1134 VAL A CA    1 
ATOM   1080 C CA    B VAL A 1 128 ? 0.19879   -25.49320 23.96131  0.492 13.14476  ? 1134 VAL A CA    1 
ATOM   1081 C C     A VAL A 1 128 ? 1.64829   -25.56007 24.31594  0.508 11.80125  ? 1134 VAL A C     1 
ATOM   1082 C C     B VAL A 1 128 ? 1.67671   -25.26396 24.26480  0.492 12.30935  ? 1134 VAL A C     1 
ATOM   1083 O O     A VAL A 1 128 ? 1.92714   -25.11170 25.43437  0.508 10.93809  ? 1134 VAL A O     1 
ATOM   1084 O O     B VAL A 1 128 ? 2.02609   -24.71439 25.31621  0.492 12.65544  ? 1134 VAL A O     1 
ATOM   1085 C CB    A VAL A 1 128 ? 0.06600   -27.49651 23.91644  0.508 12.02528  ? 1134 VAL A CB    1 
ATOM   1086 C CB    B VAL A 1 128 ? -0.17244  -26.98629 23.97309  0.492 13.72265  ? 1134 VAL A CB    1 
ATOM   1087 C CG1   A VAL A 1 128 ? 0.55027   -28.13132 25.22205  0.508 13.26222  ? 1134 VAL A CG1   1 
ATOM   1088 C CG1   B VAL A 1 128 ? 0.40531   -27.65949 25.20697  0.492 13.81407  ? 1134 VAL A CG1   1 
ATOM   1089 C CG2   A VAL A 1 128 ? -1.37248  -27.86979 23.62700  0.508 12.38758  ? 1134 VAL A CG2   1 
ATOM   1090 C CG2   B VAL A 1 128 ? -1.67739  -27.14770 23.94659  0.492 14.22905  ? 1134 VAL A CG2   1 
ATOM   1091 N N     . CYS A 1 129 ? 2.57353   -25.71220 23.37636  1.000 12.33377  ? 1135 CYS A N     1 
ATOM   1092 C CA    . CYS A 1 129 ? 3.96727   -25.70728 23.77324  1.000 12.03441  ? 1135 CYS A CA    1 
ATOM   1093 C C     . CYS A 1 129 ? 4.48978   -24.26503 23.77311  1.000 10.85425  ? 1135 CYS A C     1 
ATOM   1094 O O     . CYS A 1 129 ? 5.32133   -23.90141 24.61641  1.000 10.86931  ? 1135 CYS A O     1 
ATOM   1095 C CB    . CYS A 1 129 ? 4.78102   -26.68279 22.89445  1.000 12.84990  ? 1135 CYS A CB    1 
ATOM   1096 S SG    . CYS A 1 129 ? 6.45380   -26.94286 23.47408  1.000 11.72045  ? 1135 CYS A SG    1 
ATOM   1097 N N     . SER A 1 130 ? 3.97525   -23.40399 22.88030  1.000 11.16200  ? 1136 SER A N     1 
ATOM   1098 C CA    . SER A 1 130 ? 4.44320   -22.01464 22.87806  1.000 11.15196  ? 1136 SER A CA    1 
ATOM   1099 C C     . SER A 1 130 ? 4.01960   -21.27734 24.14193  1.000 11.14531  ? 1136 SER A C     1 
ATOM   1100 O O     . SER A 1 130 ? 4.80908   -20.50488 24.70712  1.000 11.52564  ? 1136 SER A O     1 
ATOM   1101 C CB    . SER A 1 130 ? 4.01101   -21.26546 21.61983  1.000 11.30070  ? 1136 SER A CB    1 
ATOM   1102 O OG    . SER A 1 130 ? 2.59396   -21.17642 21.52283  1.000 11.67413  ? 1136 SER A OG    1 
ATOM   1103 N N     . ASN A 1 131 ? 2.78704   -21.50733 24.60135  1.000 11.97996  ? 1137 ASN A N     1 
ATOM   1104 C CA    . ASN A 1 131 ? 2.35018   -20.91845 25.86127  1.000 12.71564  ? 1137 ASN A CA    1 
ATOM   1105 C C     . ASN A 1 131 ? 3.09782   -21.52818 27.03840  1.000 11.98161  ? 1137 ASN A C     1 
ATOM   1106 O O     . ASN A 1 131 ? 3.48478   -20.81300 27.96927  1.000 11.99139  ? 1137 ASN A O     1 
ATOM   1107 C CB    . ASN A 1 131 ? 0.84449   -21.12156 25.98784  1.000 14.10348  ? 1137 ASN A CB    1 
ATOM   1108 C CG    . ASN A 1 131 ? 0.07495   -20.08134 25.23147  1.000 16.04817  ? 1137 ASN A CG    1 
ATOM   1109 O OD1   . ASN A 1 131 ? -0.09762  -18.95823 25.70598  1.000 15.82953  ? 1137 ASN A OD1   1 
ATOM   1110 N ND2   . ASN A 1 131 ? -0.25085  -20.38897 23.97910  1.000 15.54681  ? 1137 ASN A ND2   1 
ATOM   1111 N N     . PHE A 1 132 ? 3.30856   -22.84664 27.01285  1.000 12.32261  ? 1138 PHE A N     1 
ATOM   1112 C CA    . PHE A 1 132 ? 4.07709   -23.50780 28.06125  1.000 11.88267  ? 1138 PHE A CA    1 
ATOM   1113 C C     . PHE A 1 132 ? 5.44187   -22.85088 28.21343  1.000 10.66905  ? 1138 PHE A C     1 
ATOM   1114 O O     . PHE A 1 132 ? 5.86999   -22.50442 29.32362  1.000 11.05750  ? 1138 PHE A O     1 
ATOM   1115 C CB    . PHE A 1 132 ? 4.20523   -24.99313 27.71565  1.000 11.65872  ? 1138 PHE A CB    1 
ATOM   1116 C CG    . PHE A 1 132 ? 5.20381   -25.74197 28.55328  1.000 11.42419  ? 1138 PHE A CG    1 
ATOM   1117 C CD1   . PHE A 1 132 ? 5.00060   -25.91498 29.92188  1.000 11.47540  ? 1138 PHE A CD1   1 
ATOM   1118 C CD2   . PHE A 1 132 ? 6.34220   -26.29294 27.97916  1.000 12.40322  ? 1138 PHE A CD2   1 
ATOM   1119 C CE1   . PHE A 1 132 ? 5.92187   -26.62094 30.69433  1.000 12.70286  ? 1138 PHE A CE1   1 
ATOM   1120 C CE2   . PHE A 1 132 ? 7.25618   -26.99724 28.74188  1.000 13.04712  ? 1138 PHE A CE2   1 
ATOM   1121 C CZ    . PHE A 1 132 ? 7.04333   -27.16237 30.09632  1.000 12.78978  ? 1138 PHE A CZ    1 
ATOM   1122 N N     . LEU A 1 133 ? 6.13265   -22.64058 27.08991  1.000 10.45448  ? 1139 LEU A N     1 
ATOM   1123 C CA    . LEU A 1 133 ? 7.45924   -22.03596 27.13558  1.000 10.22886  ? 1139 LEU A CA    1 
ATOM   1124 C C     . LEU A 1 133 ? 7.39464   -20.58404 27.59604  1.000 10.05731  ? 1139 LEU A C     1 
ATOM   1125 O O     . LEU A 1 133 ? 8.12928   -20.17685 28.50575  1.000 10.56766  ? 1139 LEU A O     1 
ATOM   1126 C CB    . LEU A 1 133 ? 8.13286   -22.16182 25.77094  1.000 10.49708  ? 1139 LEU A CB    1 
ATOM   1127 C CG    . LEU A 1 133 ? 8.56957   -23.58981 25.43475  1.000 10.90263  ? 1139 LEU A CG    1 
ATOM   1128 C CD1   . LEU A 1 133 ? 8.95335   -23.70576 23.97833  1.000 11.58301  ? 1139 LEU A CD1   1 
ATOM   1129 C CD2   . LEU A 1 133 ? 9.71705   -24.03597 26.32445  1.000 12.44323  ? 1139 LEU A CD2   1 
ATOM   1130 N N     . CYS A 1 134 ? 6.50189   -19.78768 27.00386  1.000 10.46180  ? 1140 CYS A N     1 
ATOM   1131 C CA    . CYS A 1 134 ? 6.44172   -18.38015 27.37327  1.000 11.52569  ? 1140 CYS A CA    1 
ATOM   1132 C C     . CYS A 1 134 ? 5.94787   -18.16589 28.79678  1.000 11.19214  ? 1140 CYS A C     1 
ATOM   1133 O O     . CYS A 1 134 ? 6.21054   -17.10398 29.37126  1.000 11.61379  ? 1140 CYS A O     1 
ATOM   1134 C CB    . CYS A 1 134 ? 5.59240   -17.58742 26.38232  1.000 13.43009  ? 1140 CYS A CB    1 
ATOM   1135 S SG    . CYS A 1 134 ? 6.37285   -17.38443 24.76833  1.000 15.34866  ? 1140 CYS A SG    1 
ATOM   1136 N N     . ASN A 1 135 ? 5.24153   -19.13972 29.37410  1.000 10.98923  ? 1141 ASN A N     1 
ATOM   1137 C CA    . ASN A 1 135 ? 4.78551   -19.07876 30.76018  1.000 10.98009  ? 1141 ASN A CA    1 
ATOM   1138 C C     . ASN A 1 135 ? 5.81391   -19.63027 31.73797  1.000 10.87501  ? 1141 ASN A C     1 
ATOM   1139 O O     . ASN A 1 135 ? 5.56675   -19.62447 32.95197  1.000 10.84973  ? 1141 ASN A O     1 
ATOM   1140 C CB    . ASN A 1 135 ? 3.48012   -19.86530 30.91646  1.000 11.77482  ? 1141 ASN A CB    1 
ATOM   1141 C CG    . ASN A 1 135 ? 2.30496   -19.16375 30.29859  1.000 12.31325  ? 1141 ASN A CG    1 
ATOM   1142 O OD1   . ASN A 1 135 ? 2.30453   -17.94009 30.14673  1.000 13.03740  ? 1141 ASN A OD1   1 
ATOM   1143 N ND2   . ASN A 1 135 ? 1.28563   -19.93157 29.93026  1.000 12.89280  ? 1141 ASN A ND2   1 
ATOM   1144 N N     . SER A 1 136 ? 6.93149   -20.14487 31.24396  1.000 10.57100  ? 1142 SER A N     1 
ATOM   1145 C CA    . SER A 1 136 ? 7.89772   -20.79182 32.11243  1.000 10.53268  ? 1142 SER A CA    1 
ATOM   1146 C C     . SER A 1 136 ? 8.64587   -19.77516 32.96833  1.000 10.29884  ? 1142 SER A C     1 
ATOM   1147 O O     . SER A 1 136 ? 8.70607   -18.57847 32.66365  1.000 11.38853  ? 1142 SER A O     1 
ATOM   1148 C CB    . SER A 1 136 ? 8.88691   -21.62711 31.30440  1.000 10.73119  ? 1142 SER A CB    1 
ATOM   1149 O OG    . SER A 1 136 ? 8.25256   -22.75453 30.72979  1.000 10.12506  ? 1142 SER A OG    1 
ATOM   1150 N N     . LYS A 1 137 ? 9.22542   -20.27367 34.05403  1.000 10.42599  ? 1143 LYS A N     1 
ATOM   1151 C CA    . LYS A 1 137 ? 9.93675   -19.45802 35.02208  1.000 10.25751  ? 1143 LYS A CA    1 
ATOM   1152 C C     . LYS A 1 137 ? 11.23766  -20.14664 35.39264  1.000 9.68022   ? 1143 LYS A C     1 
ATOM   1153 O O     . LYS A 1 137 ? 11.35322  -21.37276 35.27207  1.000 9.75966   ? 1143 LYS A O     1 
ATOM   1154 C CB    . LYS A 1 137 ? 9.10771   -19.26051 36.29947  1.000 11.69135  ? 1143 LYS A CB    1 
ATOM   1155 C CG    . LYS A 1 137 ? 7.79092   -18.56094 36.06961  1.000 13.12273  ? 1143 LYS A CG    1 
ATOM   1156 C CD    . LYS A 1 137 ? 7.99453   -17.08242 35.81552  1.000 15.38342  ? 1143 LYS A CD    1 
ATOM   1157 C CE    . LYS A 1 137 ? 6.66661   -16.38704 35.57056  1.000 19.72442  ? 1143 LYS A CE    1 
ATOM   1158 N NZ    . LYS A 1 137 ? 6.86009   -14.93292 35.31324  1.000 23.26877  ? 1143 LYS A NZ    1 
ATOM   1159 N N     . PRO A 1 138 ? 12.22037  -19.39030 35.88304  1.000 10.74873  ? 1144 PRO A N     1 
ATOM   1160 C CA    . PRO A 1 138 ? 13.47539  -20.00265 36.32960  1.000 10.31261  ? 1144 PRO A CA    1 
ATOM   1161 C C     . PRO A 1 138 ? 13.22908  -21.18986 37.24653  1.000 10.18075  ? 1144 PRO A C     1 
ATOM   1162 O O     . PRO A 1 138 ? 12.40489  -21.13775 38.16565  1.000 10.76629  ? 1144 PRO A O     1 
ATOM   1163 C CB    . PRO A 1 138 ? 14.18226  -18.85706 37.06373  1.000 11.64281  ? 1144 PRO A CB    1 
ATOM   1164 C CG    . PRO A 1 138 ? 13.67137  -17.62720 36.37368  1.000 11.88378  ? 1144 PRO A CG    1 
ATOM   1165 C CD    . PRO A 1 138 ? 12.22842  -17.92872 36.07586  1.000 11.61177  ? 1144 PRO A CD    1 
ATOM   1166 N N     . GLY A 1 139 ? 13.94502  -22.27762 36.97532  1.000 10.06810  ? 1145 GLY A N     1 
ATOM   1167 C CA    . GLY A 1 139 ? 13.83326  -23.48465 37.74712  1.000 9.92042   ? 1145 GLY A CA    1 
ATOM   1168 C C     . GLY A 1 139 ? 12.84045  -24.49154 37.20645  1.000 10.12741  ? 1145 GLY A C     1 
ATOM   1169 O O     . GLY A 1 139 ? 12.88632  -25.65625 37.60389  1.000 11.13063  ? 1145 GLY A O     1 
ATOM   1170 N N     . ASP A 1 140 ? 11.92646  -24.07505 36.33242  1.000 9.46299   ? 1146 ASP A N     1 
ATOM   1171 C CA    . ASP A 1 140 ? 10.99804  -25.02696 35.74347  1.000 9.56174   ? 1146 ASP A CA    1 
ATOM   1172 C C     . ASP A 1 140 ? 11.75844  -26.04609 34.89915  1.000 9.54820   ? 1146 ASP A C     1 
ATOM   1173 O O     . ASP A 1 140 ? 12.80994  -25.75081 34.31870  1.000 10.84772  ? 1146 ASP A O     1 
ATOM   1174 C CB    . ASP A 1 140 ? 9.99399   -24.31323 34.84675  1.000 9.52638   ? 1146 ASP A CB    1 
ATOM   1175 C CG    . ASP A 1 140 ? 8.91432   -23.57113 35.61040  1.000 9.07024   ? 1146 ASP A CG    1 
ATOM   1176 O OD1   . ASP A 1 140 ? 8.75539   -23.74730 36.84816  1.000 10.32400  ? 1146 ASP A OD1   1 
ATOM   1177 O OD2   . ASP A 1 140 ? 8.17710   -22.82756 34.91723  1.000 9.71798   ? 1146 ASP A OD2   1 
ATOM   1178 N N     . LYS A 1 141 ? 11.19870  -27.25177 34.80715  1.000 9.70489   ? 1147 LYS A N     1 
ATOM   1179 C CA    . LYS A 1 141 ? 11.78395  -28.33116 34.02636  1.000 10.17687  ? 1147 LYS A CA    1 
ATOM   1180 C C     . LYS A 1 141 ? 11.12643  -28.44294 32.65692  1.000 11.27971  ? 1147 LYS A C     1 
ATOM   1181 O O     . LYS A 1 141 ? 9.91639   -28.24439 32.50927  1.000 13.28566  ? 1147 LYS A O     1 
ATOM   1182 C CB    . LYS A 1 141 ? 11.72128  -29.67217 34.76255  1.000 11.29734  ? 1147 LYS A CB    1 
ATOM   1183 C CG    . LYS A 1 141 ? 12.17908  -29.56234 36.18942  1.000 12.61988  ? 1147 LYS A CG    1 
ATOM   1184 C CD    . LYS A 1 141 ? 13.62241  -29.11328 36.22482  1.000 13.82461  ? 1147 LYS A CD    1 
ATOM   1185 C CE    . LYS A 1 141 ? 14.22840  -29.32519 37.57295  1.000 16.27072  ? 1147 LYS A CE    1 
ATOM   1186 N NZ    . LYS A 1 141 ? 15.50878  -28.64921 37.64926  1.000 18.48190  ? 1147 LYS A NZ    1 
ATOM   1187 N N     . ILE A 1 142 ? 11.95001  -28.76043 31.65612  1.000 10.93409  ? 1148 ILE A N     1 
ATOM   1188 C CA    . ILE A 1 142 ? 11.55917  -28.86487 30.25345  1.000 14.00918  ? 1148 ILE A CA    1 
ATOM   1189 C C     . ILE A 1 142 ? 12.05117  -30.21005 29.73951  1.000 13.02324  ? 1148 ILE A C     1 
ATOM   1190 O O     . ILE A 1 142 ? 13.22000  -30.55528 29.94020  1.000 14.81109  ? 1148 ILE A O     1 
ATOM   1191 C CB    . ILE A 1 142 ? 12.23372  -27.75583 29.41189  1.000 16.82051  ? 1148 ILE A CB    1 
ATOM   1192 C CG1   . ILE A 1 142 ? 11.96643  -26.39150 30.02454  1.000 17.48408  ? 1148 ILE A CG1   1 
ATOM   1193 C CG2   . ILE A 1 142 ? 11.77540  -27.79018 27.96032  1.000 18.04307  ? 1148 ILE A CG2   1 
ATOM   1194 C CD1   . ILE A 1 142 ? 10.55829  -25.96992 29.88079  1.000 17.61261  ? 1148 ILE A CD1   1 
ATOM   1195 N N     . GLN A 1 143 ? 11.19101  -30.93974 29.02441  1.000 11.89746  ? 1149 GLN A N     1 
ATOM   1196 C CA    . GLN A 1 143 ? 11.58662  -32.18272 28.36505  1.000 11.88287  ? 1149 GLN A CA    1 
ATOM   1197 C C     . GLN A 1 143 ? 12.11714  -31.83507 26.97852  1.000 10.72211  ? 1149 GLN A C     1 
ATOM   1198 O O     . GLN A 1 143 ? 11.35052  -31.43212 26.09511  1.000 11.65695  ? 1149 GLN A O     1 
ATOM   1199 C CB    . GLN A 1 143 ? 10.40231  -33.14060 28.26906  1.000 13.81728  ? 1149 GLN A CB    1 
ATOM   1200 C CG    . GLN A 1 143 ? 9.88355   -33.61701 29.61385  1.000 16.06375  ? 1149 GLN A CG    1 
ATOM   1201 C CD    . GLN A 1 143 ? 10.91115  -34.43150 30.35922  1.000 18.08435  ? 1149 GLN A CD    1 
ATOM   1202 O OE1   . GLN A 1 143 ? 11.64158  -33.90419 31.19634  1.000 18.79577  ? 1149 GLN A OE1   1 
ATOM   1203 N NE2   . GLN A 1 143 ? 10.96905  -35.72632 30.06981  1.000 21.44813  ? 1149 GLN A NE2   1 
ATOM   1204 N N     . LEU A 1 144 ? 13.42349  -31.99455 26.80125  1.000 11.26721  ? 1150 LEU A N     1 
ATOM   1205 C CA    . LEU A 1 144 ? 14.14065  -31.56148 25.62033  1.000 11.07231  ? 1150 LEU A CA    1 
ATOM   1206 C C     . LEU A 1 144 ? 14.54326  -32.77755 24.79645  1.000 11.30318  ? 1150 LEU A C     1 
ATOM   1207 O O     . LEU A 1 144 ? 15.00574  -33.78896 25.34401  1.000 12.27493  ? 1150 LEU A O     1 
ATOM   1208 C CB    . LEU A 1 144 ? 15.36230  -30.78129 26.10075  1.000 14.58665  ? 1150 LEU A CB    1 
ATOM   1209 C CG    . LEU A 1 144 ? 16.08554  -29.84900 25.15463  1.000 15.19686  ? 1150 LEU A CG    1 
ATOM   1210 C CD1   . LEU A 1 144 ? 15.18736  -28.66745 24.86683  1.000 15.43783  ? 1150 LEU A CD1   1 
ATOM   1211 C CD2   . LEU A 1 144 ? 17.34077  -29.36640 25.84398  1.000 14.06338  ? 1150 LEU A CD2   1 
ATOM   1212 N N     . THR A 1 145 ? 14.35248  -32.68308 23.47601  1.000 11.68122  ? 1151 THR A N     1 
ATOM   1213 C CA    . THR A 1 145 ? 14.79158  -33.72753 22.56409  1.000 11.89522  ? 1151 THR A CA    1 
ATOM   1214 C C     . THR A 1 145 ? 15.65616  -33.12108 21.46613  1.000 11.50907  ? 1151 THR A C     1 
ATOM   1215 O O     . THR A 1 145 ? 15.69290  -31.90174 21.26042  1.000 11.20950  ? 1151 THR A O     1 
ATOM   1216 C CB    . THR A 1 145 ? 13.61606  -34.48793 21.93571  1.000 13.53001  ? 1151 THR A CB    1 
ATOM   1217 O OG1   . THR A 1 145 ? 12.86143  -33.59352 21.11070  1.000 13.58152  ? 1151 THR A OG1   1 
ATOM   1218 C CG2   . THR A 1 145 ? 12.70621  -35.07357 23.01276  1.000 14.68102  ? 1151 THR A CG2   1 
ATOM   1219 N N     . GLY A 1 146 ? 16.34830  -34.00104 20.74894  1.000 11.58414  ? 1152 GLY A N     1 
ATOM   1220 C CA    . GLY A 1 146 ? 17.16890  -33.59473 19.63974  1.000 11.78733  ? 1152 GLY A CA    1 
ATOM   1221 C C     . GLY A 1 146 ? 18.63443  -33.56230 20.01360  1.000 10.59898  ? 1152 GLY A C     1 
ATOM   1222 O O     . GLY A 1 146 ? 19.10772  -34.39015 20.79426  1.000 11.02304  ? 1152 GLY A O     1 
ATOM   1223 N N     . PRO A 1 147 ? 19.39432  -32.60405 19.45942  1.000 10.73551  ? 1153 PRO A N     1 
ATOM   1224 C CA    . PRO A 1 147 ? 18.91862  -31.61733 18.49231  1.000 10.57636  ? 1153 PRO A CA    1 
ATOM   1225 C C     . PRO A 1 147 ? 18.62009  -32.29567 17.16892  1.000 10.28569  ? 1153 PRO A C     1 
ATOM   1226 O O     . PRO A 1 147 ? 18.89230  -33.49376 16.98775  1.000 11.87481  ? 1153 PRO A O     1 
ATOM   1227 C CB    . PRO A 1 147 ? 20.10721  -30.66601 18.35125  1.000 11.84071  ? 1153 PRO A CB    1 
ATOM   1228 C CG    . PRO A 1 147 ? 21.28548  -31.52670 18.58910  1.000 12.05383  ? 1153 PRO A CG    1 
ATOM   1229 C CD    . PRO A 1 147 ? 20.86303  -32.57439 19.59478  1.000 11.14609  ? 1153 PRO A CD    1 
ATOM   1230 N N     . SER A 1 148 ? 18.04491  -31.54660 16.24083  1.000 10.91915  ? 1154 SER A N     1 
ATOM   1231 C CA    . SER A 1 148 ? 17.85388  -32.12335 14.92488  1.000 13.16179  ? 1154 SER A CA    1 
ATOM   1232 C C     . SER A 1 148 ? 17.94322  -31.03161 13.87884  1.000 12.74323  ? 1154 SER A C     1 
ATOM   1233 O O     . SER A 1 148 ? 17.94156  -29.83344 14.17578  1.000 13.24075  ? 1154 SER A O     1 
ATOM   1234 C CB    . SER A 1 148 ? 16.51872  -32.84764 14.78496  1.000 14.77409  ? 1154 SER A CB    1 
ATOM   1235 O OG    . SER A 1 148 ? 15.45929  -31.96333 15.04474  1.000 14.74572  ? 1154 SER A OG    1 
ATOM   1236 N N     . GLY A 1 149 ? 18.00554  -31.47847 12.63827  1.000 13.29490  ? 1155 GLY A N     1 
ATOM   1237 C CA    . GLY A 1 149 ? 18.03658  -30.57733 11.51644  1.000 13.93775  ? 1155 GLY A CA    1 
ATOM   1238 C C     . GLY A 1 149 ? 19.43371  -30.37907 10.98223  1.000 12.48808  ? 1155 GLY A C     1 
ATOM   1239 O O     . GLY A 1 149 ? 20.40833  -30.24469 11.73754  1.000 14.04628  ? 1155 GLY A O     1 
ATOM   1240 N N     . LYS A 1 150 ? 19.52711  -30.36665 9.65590   1.000 11.96934  ? 1156 LYS A N     1 
ATOM   1241 C CA    . LYS A 1 150 ? 20.74461  -29.98945 8.96456   1.000 12.61373  ? 1156 LYS A CA    1 
ATOM   1242 C C     . LYS A 1 150 ? 20.56317  -28.91118 7.91124   1.000 12.01101  ? 1156 LYS A C     1 
ATOM   1243 O O     . LYS A 1 150 ? 21.56767  -28.38221 7.42983   1.000 12.70566  ? 1156 LYS A O     1 
ATOM   1244 C CB    . LYS A 1 150 ? 21.44935  -31.21057 8.34733   1.000 16.30036  ? 1156 LYS A CB    1 
ATOM   1245 C CG    . LYS A 1 150 ? 21.89659  -32.20370 9.40824   1.000 20.10703  ? 1156 LYS A CG    1 
ATOM   1246 C CD    . LYS A 1 150 ? 22.61482  -33.44250 8.88687   1.000 25.38649  ? 1156 LYS A CD    1 
ATOM   1247 C CE    . LYS A 1 150 ? 21.90438  -34.10245 7.73512   1.000 29.18991  ? 1156 LYS A CE    1 
ATOM   1248 N NZ    . LYS A 1 150 ? 22.84060  -34.97609 6.96890   1.000 31.70511  ? 1156 LYS A NZ    1 
ATOM   1249 N N     . ILE A 1 151 ? 19.33002  -28.53981 7.56311   1.000 12.37004  ? 1157 ILE A N     1 
ATOM   1250 C CA    . ILE A 1 151 ? 19.12624  -27.62108 6.44537   1.000 12.94968  ? 1157 ILE A CA    1 
ATOM   1251 C C     . ILE A 1 151 ? 19.79218  -26.28420 6.70246   1.000 11.46666  ? 1157 ILE A C     1 
ATOM   1252 O O     . ILE A 1 151 ? 20.26619  -25.62904 5.76183   1.000 12.54470  ? 1157 ILE A O     1 
ATOM   1253 C CB    . ILE A 1 151 ? 17.62145  -27.44446 6.18279   1.000 15.33145  ? 1157 ILE A CB    1 
ATOM   1254 C CG1   . ILE A 1 151 ? 17.07916  -28.66293 5.45677   1.000 18.06244  ? 1157 ILE A CG1   1 
ATOM   1255 C CG2   . ILE A 1 151 ? 17.34328  -26.21543 5.33434   1.000 16.58095  ? 1157 ILE A CG2   1 
ATOM   1256 C CD1   . ILE A 1 151 ? 15.57886  -28.71700 5.45711   1.000 19.74704  ? 1157 ILE A CD1   1 
ATOM   1257 N N     . MET A 1 152 ? 19.85196  -25.86041 7.96256   1.000 10.76616  ? 1158 MET A N     1 
ATOM   1258 C CA    . MET A 1 152 ? 20.23146  -24.49681 8.26977   1.000 10.61991  ? 1158 MET A CA    1 
ATOM   1259 C C     . MET A 1 152 ? 21.61585  -24.46940 8.94302   1.000 9.99895   ? 1158 MET A C     1 
ATOM   1260 O O     . MET A 1 152 ? 21.99283  -23.47496 9.58080   1.000 10.26795  ? 1158 MET A O     1 
ATOM   1261 C CB    . MET A 1 152 ? 19.17008  -23.97854 9.21969   1.000 12.68522  ? 1158 MET A CB    1 
ATOM   1262 C CG    . MET A 1 152 ? 17.88116  -23.44474 8.58356   1.000 12.26921  ? 1158 MET A CG    1 
ATOM   1263 S SD    . MET A 1 152 ? 17.83434  -22.57336 7.03340   1.000 12.00530  ? 1158 MET A SD    1 
ATOM   1264 C CE    . MET A 1 152 ? 17.67340  -20.93336 7.72213   1.000 14.10532  ? 1158 MET A CE    1 
ATOM   1265 N N     . LEU A 1 153 ? 22.39780  -25.54217 8.81523   1.000 10.02655  ? 1159 LEU A N     1 
ATOM   1266 C CA    . LEU A 1 153 ? 23.78228  -25.48227 9.26077   1.000 10.59970  ? 1159 LEU A CA    1 
ATOM   1267 C C     . LEU A 1 153 ? 24.52146  -24.39469 8.48928   1.000 11.10303  ? 1159 LEU A C     1 
ATOM   1268 O O     . LEU A 1 153 ? 24.24739  -24.13734 7.31479   1.000 13.14520  ? 1159 LEU A O     1 
ATOM   1269 C CB    . LEU A 1 153 ? 24.47225  -26.83385 9.07027   1.000 11.38139  ? 1159 LEU A CB    1 
ATOM   1270 C CG    . LEU A 1 153 ? 23.90159  -28.00290 9.87906   1.000 11.75466  ? 1159 LEU A CG    1 
ATOM   1271 C CD1   . LEU A 1 153 ? 24.60257  -29.30291 9.55104   1.000 14.87682  ? 1159 LEU A CD1   1 
ATOM   1272 C CD2   . LEU A 1 153 ? 23.97320  -27.72109 11.38148  1.000 12.60317  ? 1159 LEU A CD2   1 
ATOM   1273 N N     . LEU A 1 154 ? 25.46173  -23.74077 9.16224   1.000 10.31643  ? 1160 LEU A N     1 
ATOM   1274 C CA    . LEU A 1 154 ? 26.20547  -22.66482 8.52491   1.000 10.08475  ? 1160 LEU A CA    1 
ATOM   1275 C C     . LEU A 1 154 ? 27.34103  -23.24742 7.69196   1.000 9.77377   ? 1160 LEU A C     1 
ATOM   1276 O O     . LEU A 1 154 ? 28.20380  -23.94395 8.23935   1.000 10.50106  ? 1160 LEU A O     1 
ATOM   1277 C CB    . LEU A 1 154 ? 26.78598  -21.73240 9.57199   1.000 10.32780  ? 1160 LEU A CB    1 
ATOM   1278 C CG    . LEU A 1 154 ? 27.53871  -20.51173 9.04282   1.000 10.65787  ? 1160 LEU A CG    1 
ATOM   1279 C CD1   . LEU A 1 154 ? 26.62072  -19.57087 8.26717   1.000 11.46739  ? 1160 LEU A CD1   1 
ATOM   1280 C CD2   . LEU A 1 154 ? 28.18865  -19.78718 10.19584  1.000 11.82417  ? 1160 LEU A CD2   1 
ATOM   1281 N N     . PRO A 1 155 ? 27.40584  -22.96633 6.38237   1.000 9.92869   ? 1161 PRO A N     1 
ATOM   1282 C CA    . PRO A 1 155 ? 28.56518  -23.41812 5.60263   1.000 10.89399  ? 1161 PRO A CA    1 
ATOM   1283 C C     . PRO A 1 155 ? 29.79428  -22.61213 5.98339   1.000 10.38258  ? 1161 PRO A C     1 
ATOM   1284 O O     . PRO A 1 155 ? 29.85763  -21.40662 5.71095   1.000 11.12239  ? 1161 PRO A O     1 
ATOM   1285 C CB    . PRO A 1 155 ? 28.13935  -23.16616 4.14803   1.000 12.68969  ? 1161 PRO A CB    1 
ATOM   1286 C CG    . PRO A 1 155 ? 26.63976  -23.00121 4.19741   1.000 13.08981  ? 1161 PRO A CG    1 
ATOM   1287 C CD    . PRO A 1 155 ? 26.36595  -22.37238 5.52442   1.000 10.86833  ? 1161 PRO A CD    1 
ATOM   1288 N N     . GLU A 1 156 ? 30.77252  -23.26639 6.61293   1.000 10.75330  ? 1162 GLU A N     1 
ATOM   1289 C CA    . GLU A 1 156 ? 31.96694  -22.60638 7.12492   1.000 11.35803  ? 1162 GLU A CA    1 
ATOM   1290 C C     . GLU A 1 156 ? 33.21134  -22.87789 6.29219   1.000 12.54784  ? 1162 GLU A C     1 
ATOM   1291 O O     . GLU A 1 156 ? 34.27592  -22.34888 6.61656   1.000 14.85176  ? 1162 GLU A O     1 
ATOM   1292 C CB    . GLU A 1 156 ? 32.21085  -22.98640 8.59174   1.000 11.42210  ? 1162 GLU A CB    1 
ATOM   1293 C CG    . GLU A 1 156 ? 31.08577  -22.52780 9.48131   1.000 11.31018  ? 1162 GLU A CG    1 
ATOM   1294 C CD    . GLU A 1 156 ? 31.30848  -22.80795 10.94887  1.000 12.86078  ? 1162 GLU A CD    1 
ATOM   1295 O OE1   . GLU A 1 156 ? 32.39034  -23.29558 11.34821  1.000 16.29423  ? 1162 GLU A OE1   1 
ATOM   1296 O OE2   . GLU A 1 156 ? 30.37128  -22.52274 11.71228  1.000 15.76231  ? 1162 GLU A OE2   1 
ATOM   1297 N N     . GLU A 1 157 ? 33.10187  -23.67169 5.22265   1.000 12.62387  ? 1163 GLU A N     1 
ATOM   1298 C CA    . GLU A 1 157 ? 34.26467  -24.00985 4.40230   1.000 14.53394  ? 1163 GLU A CA    1 
ATOM   1299 C C     . GLU A 1 157 ? 34.97932  -22.75946 3.90537   1.000 13.38532  ? 1163 GLU A C     1 
ATOM   1300 O O     . GLU A 1 157 ? 36.21341  -22.72781 3.81564   1.000 14.71887  ? 1163 GLU A O     1 
ATOM   1301 C CB    . GLU A 1 157 ? 33.81776  -24.84215 3.19660   1.000 17.85739  ? 1163 GLU A CB    1 
ATOM   1302 C CG    . GLU A 1 157 ? 33.29650  -26.23778 3.51188   1.000 23.50528  ? 1163 GLU A CG    1 
ATOM   1303 C CD    . GLU A 1 157 ? 31.90516  -26.24125 4.14632   1.000 26.37206  ? 1163 GLU A CD    1 
ATOM   1304 O OE1   . GLU A 1 157 ? 31.09947  -25.31337 3.88703   1.000 23.13166  ? 1163 GLU A OE1   1 
ATOM   1305 O OE2   . GLU A 1 157 ? 31.61013  -27.19171 4.90487   1.000 30.69691  ? 1163 GLU A OE2   1 
ATOM   1306 N N     . ASP A 1 158 ? 34.21798  -21.73338 3.54233   1.000 12.18815  ? 1164 ASP A N     1 
ATOM   1307 C CA    . ASP A 1 158 ? 34.77399  -20.46328 3.09886   1.000 12.33699  ? 1164 ASP A CA    1 
ATOM   1308 C C     . ASP A 1 158 ? 34.51330  -19.43880 4.19419   1.000 12.09908  ? 1164 ASP A C     1 
ATOM   1309 O O     . ASP A 1 158 ? 33.38032  -18.95043 4.32649   1.000 11.45380  ? 1164 ASP A O     1 
ATOM   1310 C CB    . ASP A 1 158 ? 34.10014  -20.03444 1.79373   1.000 12.53514  ? 1164 ASP A CB    1 
ATOM   1311 C CG    . ASP A 1 158 ? 34.58840  -18.68898 1.30136   1.000 13.49032  ? 1164 ASP A CG    1 
ATOM   1312 O OD1   . ASP A 1 158 ? 35.53941  -18.14271 1.90318   1.000 13.67942  ? 1164 ASP A OD1   1 
ATOM   1313 O OD2   . ASP A 1 158 ? 34.02043  -18.18688 0.30302   1.000 15.24179  ? 1164 ASP A OD2   1 
ATOM   1314 N N     . PRO A 1 159 ? 35.50863  -19.08347 5.01349   1.000 13.03332  ? 1165 PRO A N     1 
ATOM   1315 C CA    . PRO A 1 159 ? 35.27329  -18.08516 6.06598   1.000 13.15417  ? 1165 PRO A CA    1 
ATOM   1316 C C     . PRO A 1 159 ? 35.06276  -16.68045 5.53440   1.000 12.55945  ? 1165 PRO A C     1 
ATOM   1317 O O     . PRO A 1 159 ? 34.76902  -15.78033 6.32980   1.000 13.13879  ? 1165 PRO A O     1 
ATOM   1318 C CB    . PRO A 1 159 ? 36.53896  -18.18045 6.92393   1.000 15.70375  ? 1165 PRO A CB    1 
ATOM   1319 C CG    . PRO A 1 159 ? 37.58210  -18.63679 5.97867   1.000 16.42723  ? 1165 PRO A CG    1 
ATOM   1320 C CD    . PRO A 1 159 ? 36.90501  -19.55365 4.99741   1.000 14.70947  ? 1165 PRO A CD    1 
ATOM   1321 N N     . ASN A 1 160 ? 35.20300  -16.47347 4.22224   1.000 12.65128  ? 1166 ASN A N     1 
ATOM   1322 C CA    . ASN A 1 160 ? 34.90913  -15.19869 3.58345   1.000 12.59227  ? 1166 ASN A CA    1 
ATOM   1323 C C     . ASN A 1 160 ? 33.68816  -15.27705 2.67561   1.000 11.96139  ? 1166 ASN A C     1 
ATOM   1324 O O     . ASN A 1 160 ? 33.51852  -14.43746 1.78662   1.000 12.64441  ? 1166 ASN A O     1 
ATOM   1325 C CB    . ASN A 1 160 ? 36.14806  -14.69256 2.85300   1.000 15.14484  ? 1166 ASN A CB    1 
ATOM   1326 C CG    . ASN A 1 160 ? 37.33084  -14.59738 3.78673   1.000 17.38675  ? 1166 ASN A CG    1 
ATOM   1327 O OD1   . ASN A 1 160 ? 37.22259  -14.03349 4.87496   1.000 18.07152  ? 1166 ASN A OD1   1 
ATOM   1328 N ND2   . ASN A 1 160 ? 38.45159  -15.18798 3.39360   1.000 19.68815  ? 1166 ASN A ND2   1 
ATOM   1329 N N     . ALA A 1 161 ? 32.82918  -16.26535 2.89681   1.000 11.35695  ? 1167 ALA A N     1 
ATOM   1330 C CA    . ALA A 1 161 ? 31.59161  -16.38505 2.14788   1.000 11.21960  ? 1167 ALA A CA    1 
ATOM   1331 C C     . ALA A 1 161 ? 30.66474  -15.20545 2.43050   1.000 10.40573  ? 1167 ALA A C     1 
ATOM   1332 O O     . ALA A 1 161 ? 30.83401  -14.44201 3.38792   1.000 11.79475  ? 1167 ALA A O     1 
ATOM   1333 C CB    . ALA A 1 161 ? 30.88187  -17.69165 2.50657   1.000 11.52434  ? 1167 ALA A CB    1 
ATOM   1334 N N     . THR A 1 162 ? 29.66613  -15.06379 1.56819   1.000 10.14643  ? 1168 THR A N     1 
ATOM   1335 C CA    . THR A 1 162 ? 28.58490  -14.11481 1.77068   1.000 10.21556  ? 1168 THR A CA    1 
ATOM   1336 C C     . THR A 1 162 ? 27.33036  -14.87755 2.15775   1.000 9.40449   ? 1168 THR A C     1 
ATOM   1337 O O     . THR A 1 162 ? 27.00977  -15.90392 1.54835   1.000 9.96816   ? 1168 THR A O     1 
ATOM   1338 C CB    . THR A 1 162 ? 28.36753  -13.27298 0.51714   1.000 10.95915  ? 1168 THR A CB    1 
ATOM   1339 O OG1   . THR A 1 162 ? 29.53087  -12.46916 0.30656   1.000 14.05539  ? 1168 THR A OG1   1 
ATOM   1340 C CG2   . THR A 1 162 ? 27.17614  -12.34203 0.67597   1.000 11.44807  ? 1168 THR A CG2   1 
ATOM   1341 N N     . HIS A 1 163 ? 26.65415  -14.38709 3.19827   1.000 9.08625   ? 1169 HIS A N     1 
ATOM   1342 C CA    . HIS A 1 163 ? 25.47497  -15.02175 3.77388   1.000 9.01350   ? 1169 HIS A CA    1 
ATOM   1343 C C     . HIS A 1 163 ? 24.37256  -13.97682 3.86163   1.000 8.95162   ? 1169 HIS A C     1 
ATOM   1344 O O     . HIS A 1 163 ? 24.46541  -13.03761 4.65938   1.000 9.53680   ? 1169 HIS A O     1 
ATOM   1345 C CB    . HIS A 1 163 ? 25.78788  -15.56780 5.16104   1.000 8.87555   ? 1169 HIS A CB    1 
ATOM   1346 C CG    . HIS A 1 163 ? 26.89536  -16.56626 5.18946   1.000 9.08126   ? 1169 HIS A CG    1 
ATOM   1347 N ND1   . HIS A 1 163 ? 26.72974  -17.88192 4.80221   1.000 9.58193   ? 1169 HIS A ND1   1 
ATOM   1348 C CD2   . HIS A 1 163 ? 28.18262  -16.44288 5.59971   1.000 9.87485   ? 1169 HIS A CD2   1 
ATOM   1349 C CE1   . HIS A 1 163 ? 27.88052  -18.51555 4.95923   1.000 9.87404   ? 1169 HIS A CE1   1 
ATOM   1350 N NE2   . HIS A 1 163 ? 28.77527  -17.66837 5.44311   1.000 9.85293   ? 1169 HIS A NE2   1 
ATOM   1351 N N     . ILE A 1 164 ? 23.34438  -14.14119 3.03981   1.000 8.74483   ? 1170 ILE A N     1 
ATOM   1352 C CA    . ILE A 1 164 ? 22.19399  -13.24338 2.99559   1.000 8.95595   ? 1170 ILE A CA    1 
ATOM   1353 C C     . ILE A 1 164 ? 21.06842  -13.92283 3.76551   1.000 9.10276   ? 1170 ILE A C     1 
ATOM   1354 O O     . ILE A 1 164 ? 20.59401  -14.98426 3.35998   1.000 9.62637   ? 1170 ILE A O     1 
ATOM   1355 C CB    . ILE A 1 164 ? 21.77449  -12.94657 1.55061   1.000 9.80972   ? 1170 ILE A CB    1 
ATOM   1356 C CG1   . ILE A 1 164 ? 22.94561  -12.36384 0.75109   1.000 10.91505  ? 1170 ILE A CG1   1 
ATOM   1357 C CG2   . ILE A 1 164 ? 20.57511  -12.01839 1.53224   1.000 10.88253  ? 1170 ILE A CG2   1 
ATOM   1358 C CD1   . ILE A 1 164 ? 22.70828  -12.38469 -0.74862  1.000 12.78496  ? 1170 ILE A CD1   1 
ATOM   1359 N N     . MET A 1 165 ? 20.67232  -13.33676 4.89046   1.000 9.23615   ? 1171 MET A N     1 
ATOM   1360 C CA    . MET A 1 165 ? 19.76823  -13.95461 5.84848   1.000 9.45455   ? 1171 MET A CA    1 
ATOM   1361 C C     . MET A 1 165 ? 18.42507  -13.25221 5.83567   1.000 9.80372   ? 1171 MET A C     1 
ATOM   1362 O O     . MET A 1 165 ? 18.34357  -12.07700 6.20299   1.000 10.52626  ? 1171 MET A O     1 
ATOM   1363 C CB    . MET A 1 165 ? 20.35434  -14.03783 7.25595   1.000 10.15909  ? 1171 MET A CB    1 
ATOM   1364 C CG    . MET A 1 165 ? 21.77880  -14.54243 7.32149   1.000 10.21654  ? 1171 MET A CG    1 
ATOM   1365 S SD    . MET A 1 165 ? 22.61092  -14.13201 8.85901   1.000 9.55666   ? 1171 MET A SD    1 
ATOM   1366 C CE    . MET A 1 165 ? 24.30136  -14.54390 8.42864   1.000 11.53379  ? 1171 MET A CE    1 
ATOM   1367 N N     . ILE A 1 166 ? 17.38263  -13.97060 5.41212   1.000 9.86088   ? 1172 ILE A N     1 
ATOM   1368 C CA    . ILE A 1 166 ? 16.04780  -13.40837 5.25226   1.000 10.06541  ? 1172 ILE A CA    1 
ATOM   1369 C C     . ILE A 1 166 ? 15.14264  -14.00403 6.32163   1.000 10.12576  ? 1172 ILE A C     1 
ATOM   1370 O O     . ILE A 1 166 ? 14.79238  -15.18978 6.25796   1.000 10.89786  ? 1172 ILE A O     1 
ATOM   1371 C CB    . ILE A 1 166 ? 15.47212  -13.69745 3.85982   1.000 11.23270  ? 1172 ILE A CB    1 
ATOM   1372 C CG1   . ILE A 1 166 ? 16.46172  -13.34411 2.74338   1.000 11.63997  ? 1172 ILE A CG1   1 
ATOM   1373 C CG2   . ILE A 1 166 ? 14.14493  -12.96600 3.72038   1.000 11.92840  ? 1172 ILE A CG2   1 
ATOM   1374 C CD1   . ILE A 1 166 ? 16.93111  -11.92998 2.74435   1.000 11.49272  ? 1172 ILE A CD1   1 
ATOM   1375 N N     . ALA A 1 167 ? 14.73243  -13.18242 7.28390   1.000 10.73350  ? 1173 ALA A N     1 
ATOM   1376 C CA    . ALA A 1 167 ? 13.92583  -13.62431 8.41027   1.000 10.89056  ? 1173 ALA A CA    1 
ATOM   1377 C C     . ALA A 1 167 ? 12.61175  -12.86297 8.46135   1.000 11.93075  ? 1173 ALA A C     1 
ATOM   1378 O O     . ALA A 1 167 ? 12.55314  -11.66901 8.15891   1.000 12.42085  ? 1173 ALA A O     1 
ATOM   1379 C CB    . ALA A 1 167 ? 14.65040  -13.33762 9.72217   1.000 10.86740  ? 1173 ALA A CB    1 
ATOM   1380 N N     . THR A 1 168 ? 11.56152  -13.55387 8.89275   1.000 12.54727  ? 1174 THR A N     1 
ATOM   1381 C CA    . THR A 1 168 ? 10.38016  -12.88858 9.41846   1.000 13.74745  ? 1174 THR A CA    1 
ATOM   1382 C C     . THR A 1 168 ? 10.13786  -13.39251 10.83224  1.000 13.27650  ? 1174 THR A C     1 
ATOM   1383 O O     . THR A 1 168 ? 10.22748  -14.59441 11.09739  1.000 13.15737  ? 1174 THR A O     1 
ATOM   1384 C CB    . THR A 1 168 ? 9.12146   -13.09726 8.55439   1.000 16.62435  ? 1174 THR A CB    1 
ATOM   1385 O OG1   . THR A 1 168 ? 8.82477   -14.49254 8.42679   1.000 16.64710  ? 1174 THR A OG1   1 
ATOM   1386 C CG2   . THR A 1 168 ? 9.31464   -12.47848 7.17721   1.000 17.76732  ? 1174 THR A CG2   1 
ATOM   1387 N N     . GLY A 1 169 ? 9.82029   -12.46649 11.72790  1.000 12.96799  ? 1175 GLY A N     1 
ATOM   1388 C CA    . GLY A 1 169 ? 9.50022   -12.83698 13.09985  1.000 12.97790  ? 1175 GLY A CA    1 
ATOM   1389 C C     . GLY A 1 169 ? 10.53035  -13.75732 13.72391  1.000 12.31072  ? 1175 GLY A C     1 
ATOM   1390 O O     . GLY A 1 169 ? 11.73551  -13.49793 13.67598  1.000 11.89016  ? 1175 GLY A O     1 
ATOM   1391 N N     . THR A 1 170 ? 10.04566  -14.85231 14.32103  1.000 12.31148  ? 1176 THR A N     1 
ATOM   1392 C CA    . THR A 1 170 ? 10.90962  -15.79655 15.02455  1.000 11.24347  ? 1176 THR A CA    1 
ATOM   1393 C C     . THR A 1 170 ? 11.93655  -16.44687 14.10983  1.000 10.81445  ? 1176 THR A C     1 
ATOM   1394 O O     . THR A 1 170 ? 12.88325  -17.06419 14.61512  1.000 10.90592  ? 1176 THR A O     1 
ATOM   1395 C CB    . THR A 1 170 ? 10.07394  -16.88339 15.70450  1.000 12.02275  ? 1176 THR A CB    1 
ATOM   1396 O OG1   . THR A 1 170 ? 9.21678   -17.51327 14.74874  1.000 12.32725  ? 1176 THR A OG1   1 
ATOM   1397 C CG2   . THR A 1 170 ? 9.21640   -16.30513 16.82604  1.000 12.98105  ? 1176 THR A CG2   1 
ATOM   1398 N N     . GLY A 1 171 ? 11.76209  -16.34861 12.79195  1.000 11.16712  ? 1177 GLY A N     1 
ATOM   1399 C CA    . GLY A 1 171 ? 12.76749  -16.83309 11.86357  1.000 11.40305  ? 1177 GLY A CA    1 
ATOM   1400 C C     . GLY A 1 171 ? 14.11976  -16.17354 12.01314  1.000 10.48204  ? 1177 GLY A C     1 
ATOM   1401 O O     . GLY A 1 171 ? 15.09669  -16.65669 11.43100  1.000 10.36019  ? 1177 GLY A O     1 
ATOM   1402 N N     . VAL A 1 172 ? 14.21111  -15.10067 12.80291  1.000 10.46903  ? 1178 VAL A N     1 
ATOM   1403 C CA    . VAL A 1 172 ? 15.51323  -14.51736 13.09808  1.000 10.49909  ? 1178 VAL A CA    1 
ATOM   1404 C C     . VAL A 1 172 ? 16.39642  -15.45812 13.90870  1.000 9.36240   ? 1178 VAL A C     1 
ATOM   1405 O O     . VAL A 1 172 ? 17.62212  -15.27615 13.94590  1.000 9.73816   ? 1178 VAL A O     1 
ATOM   1406 C CB    . VAL A 1 172 ? 15.31822  -13.16529 13.80299  1.000 11.84519  ? 1178 VAL A CB    1 
ATOM   1407 C CG1   . VAL A 1 172 ? 14.94809  -13.36648 15.26545  1.000 12.75764  ? 1178 VAL A CG1   1 
ATOM   1408 C CG2   . VAL A 1 172 ? 16.53622  -12.27606 13.62496  1.000 14.24780  ? 1178 VAL A CG2   1 
ATOM   1409 N N     . ALA A 1 173 ? 15.81209  -16.47091 14.54397  1.000 9.70438   ? 1179 ALA A N     1 
ATOM   1410 C CA    . ALA A 1 173 ? 16.52532  -17.32266 15.49463  1.000 9.69830   ? 1179 ALA A CA    1 
ATOM   1411 C C     . ALA A 1 173 ? 17.85621  -17.87712 14.98812  1.000 8.59053   ? 1179 ALA A C     1 
ATOM   1412 O O     . ALA A 1 173 ? 18.88667  -17.64906 15.63092  1.000 9.18703   ? 1179 ALA A O     1 
ATOM   1413 C CB    . ALA A 1 173 ? 15.61593  -18.44539 15.99134  1.000 10.05006  ? 1179 ALA A CB    1 
ATOM   1414 N N     . PRO A 1 174 ? 17.89721  -18.64101 13.88976  1.000 9.07000   ? 1180 PRO A N     1 
ATOM   1415 C CA    . PRO A 1 174 ? 19.20401  -19.17384 13.47629  1.000 9.11857   ? 1180 PRO A CA    1 
ATOM   1416 C C     . PRO A 1 174 ? 20.20760  -18.07879 13.19765  1.000 8.45841   ? 1180 PRO A C     1 
ATOM   1417 O O     . PRO A 1 174 ? 21.41183  -18.27464 13.40756  1.000 8.90809   ? 1180 PRO A O     1 
ATOM   1418 C CB    . PRO A 1 174 ? 18.88025  -19.97577 12.20519  1.000 9.42984   ? 1180 PRO A CB    1 
ATOM   1419 C CG    . PRO A 1 174 ? 17.61026  -19.36550 11.69153  1.000 9.86696   ? 1180 PRO A CG    1 
ATOM   1420 C CD    . PRO A 1 174 ? 16.83243  -19.01950 12.93405  1.000 9.37754   ? 1180 PRO A CD    1 
ATOM   1421 N N     . PHE A 1 175 ? 19.73409  -16.93464 12.69277  1.000 8.89476   ? 1181 PHE A N     1 
ATOM   1422 C CA    . PHE A 1 175 ? 20.63288  -15.85039 12.33131  1.000 8.35150   ? 1181 PHE A CA    1 
ATOM   1423 C C     . PHE A 1 175 ? 21.24467  -15.18773 13.55638  1.000 8.44513   ? 1181 PHE A C     1 
ATOM   1424 O O     . PHE A 1 175 ? 22.38157  -14.71108 13.49757  1.000 8.76970   ? 1181 PHE A O     1 
ATOM   1425 C CB    . PHE A 1 175 ? 19.89721  -14.86924 11.42576  1.000 9.01337   ? 1181 PHE A CB    1 
ATOM   1426 C CG    . PHE A 1 175 ? 19.21099  -15.53858 10.26715  1.000 8.92524   ? 1181 PHE A CG    1 
ATOM   1427 C CD1   . PHE A 1 175 ? 19.80608  -16.60583 9.60564   1.000 9.37955   ? 1181 PHE A CD1   1 
ATOM   1428 C CD2   . PHE A 1 175 ? 17.96409  -15.12171 9.84497   1.000 10.23212  ? 1181 PHE A CD2   1 
ATOM   1429 C CE1   . PHE A 1 175 ? 19.16903  -17.23850 8.52497   1.000 10.06794  ? 1181 PHE A CE1   1 
ATOM   1430 C CE2   . PHE A 1 175 ? 17.32634  -15.74443 8.77474   1.000 10.62279  ? 1181 PHE A CE2   1 
ATOM   1431 C CZ    . PHE A 1 175 ? 17.92636  -16.80073 8.11368   1.000 10.12232  ? 1181 PHE A CZ    1 
ATOM   1432 N N     . ARG A 1 176 ? 20.50673  -15.11204 14.66186  1.000 8.90303   ? 1182 ARG A N     1 
ATOM   1433 C CA    . ARG A 1 176 ? 21.13492  -14.65479 15.89386  1.000 8.45733   ? 1182 ARG A CA    1 
ATOM   1434 C C     . ARG A 1 176 ? 22.34430  -15.52065 16.23149  1.000 8.08319   ? 1182 ARG A C     1 
ATOM   1435 O O     . ARG A 1 176 ? 23.40765  -15.00549 16.61355  1.000 8.60309   ? 1182 ARG A O     1 
ATOM   1436 C CB    . ARG A 1 176 ? 20.12592  -14.66183 17.04095  1.000 9.40697   ? 1182 ARG A CB    1 
ATOM   1437 C CG    . ARG A 1 176 ? 20.69824  -14.14258 18.34618  1.000 9.02133   ? 1182 ARG A CG    1 
ATOM   1438 C CD    . ARG A 1 176 ? 19.64286  -14.10220 19.42415  1.000 8.99807   ? 1182 ARG A CD    1 
ATOM   1439 N NE    . ARG A 1 176 ? 20.12850  -13.59961 20.70401  1.000 9.36784   ? 1182 ARG A NE    1 
ATOM   1440 C CZ    . ARG A 1 176 ? 20.64198  -14.35587 21.66926  1.000 9.31592   ? 1182 ARG A CZ    1 
ATOM   1441 N NH1   . ARG A 1 176 ? 20.78663  -15.67038 21.52394  1.000 9.52222   ? 1182 ARG A NH1   1 
ATOM   1442 N NH2   . ARG A 1 176 ? 21.01574  -13.78186 22.81360  1.000 10.15422  ? 1182 ARG A NH2   1 
ATOM   1443 N N     . GLY A 1 177 ? 22.20223  -16.84095 16.07808  1.000 8.25981   ? 1183 GLY A N     1 
ATOM   1444 C CA    . GLY A 1 177 ? 23.31939  -17.74148 16.30990  1.000 8.46640   ? 1183 GLY A CA    1 
ATOM   1445 C C     . GLY A 1 177 ? 24.43569  -17.56836 15.29794  1.000 8.38532   ? 1183 GLY A C     1 
ATOM   1446 O O     . GLY A 1 177 ? 25.61342  -17.50352 15.67171  1.000 8.95549   ? 1183 GLY A O     1 
ATOM   1447 N N     . TYR A 1 178 ? 24.09151  -17.51027 14.00742  1.000 8.57914   ? 1184 TYR A N     1 
ATOM   1448 C CA    . TYR A 1 178 ? 25.13332  -17.30813 13.00058  1.000 8.54059   ? 1184 TYR A CA    1 
ATOM   1449 C C     . TYR A 1 178 ? 25.94115  -16.06068 13.31703  1.000 8.26000   ? 1184 TYR A C     1 
ATOM   1450 O O     . TYR A 1 178 ? 27.17371  -16.06494 13.25028  1.000 8.79117   ? 1184 TYR A O     1 
ATOM   1451 C CB    . TYR A 1 178 ? 24.53525  -17.07582 11.61498  1.000 9.06677   ? 1184 TYR A CB    1 
ATOM   1452 C CG    . TYR A 1 178 ? 23.82469  -18.19465 10.89784  1.000 8.64581   ? 1184 TYR A CG    1 
ATOM   1453 C CD1   . TYR A 1 178 ? 23.73363  -19.48922 11.39212  1.000 8.81825   ? 1184 TYR A CD1   1 
ATOM   1454 C CD2   . TYR A 1 178 ? 23.22059  -17.91707 9.68202   1.000 9.40798   ? 1184 TYR A CD2   1 
ATOM   1455 C CE1   . TYR A 1 178 ? 23.03058  -20.47187 10.68735  1.000 9.58609   ? 1184 TYR A CE1   1 
ATOM   1456 C CE2   . TYR A 1 178 ? 22.54054  -18.85950 8.97222   1.000 10.21708  ? 1184 TYR A CE2   1 
ATOM   1457 C CZ    . TYR A 1 178 ? 22.43963  -20.13873 9.46750   1.000 9.59025   ? 1184 TYR A CZ    1 
ATOM   1458 O OH    . TYR A 1 178 ? 21.71561  -21.04940 8.72904   1.000 11.01199  ? 1184 TYR A OH    1 
ATOM   1459 N N     . LEU A 1 179 ? 25.23913  -14.95843 13.59592  1.000 8.67926   ? 1185 LEU A N     1 
ATOM   1460 C CA    . LEU A 1 179 ? 25.89281  -13.66257 13.69944  1.000 8.47421   ? 1185 LEU A CA    1 
ATOM   1461 C C     . LEU A 1 179 ? 26.73339  -13.56006 14.96324  1.000 8.57675   ? 1185 LEU A C     1 
ATOM   1462 O O     . LEU A 1 179 ? 27.79797  -12.93447 14.94407  1.000 9.17472   ? 1185 LEU A O     1 
ATOM   1463 C CB    . LEU A 1 179 ? 24.85748  -12.54733 13.62067  1.000 9.10200   ? 1185 LEU A CB    1 
ATOM   1464 C CG    . LEU A 1 179 ? 24.20126  -12.41606 12.23879  1.000 9.44336   ? 1185 LEU A CG    1 
ATOM   1465 C CD1   . LEU A 1 179 ? 22.96165  -11.55491 12.32974  1.000 10.63000  ? 1185 LEU A CD1   1 
ATOM   1466 C CD2   . LEU A 1 179 ? 25.19174  -11.84276 11.21328  1.000 10.60591  ? 1185 LEU A CD2   1 
ATOM   1467 N N     . ARG A 1 180 ? 26.30412  -14.18282 16.06133  1.000 8.66857   ? 1186 ARG A N     1 
ATOM   1468 C CA    . ARG A 1 180 ? 27.16524  -14.20470 17.23413  1.000 8.62837   ? 1186 ARG A CA    1 
ATOM   1469 C C     . ARG A 1 180 ? 28.44018  -14.98432 16.95394  1.000 8.48824   ? 1186 ARG A C     1 
ATOM   1470 O O     . ARG A 1 180 ? 29.52445  -14.59512 17.40105  1.000 9.21160   ? 1186 ARG A O     1 
ATOM   1471 C CB    . ARG A 1 180 ? 26.43753  -14.80627 18.43172  1.000 8.98437   ? 1186 ARG A CB    1 
ATOM   1472 C CG    . ARG A 1 180 ? 25.55334  -13.83952 19.17263  1.000 9.24454   ? 1186 ARG A CG    1 
ATOM   1473 C CD    . ARG A 1 180 ? 25.10582  -14.39740 20.50793  1.000 10.24725  ? 1186 ARG A CD    1 
ATOM   1474 N NE    . ARG A 1 180 ? 24.37748  -13.38132 21.25075  1.000 9.87768   ? 1186 ARG A NE    1 
ATOM   1475 C CZ    . ARG A 1 180 ? 24.46267  -13.19094 22.56000  1.000 9.71429   ? 1186 ARG A CZ    1 
ATOM   1476 N NH1   . ARG A 1 180 ? 25.11370  -14.03700 23.34711  1.000 10.14712  ? 1186 ARG A NH1   1 
ATOM   1477 N NH2   . ARG A 1 180 ? 23.87964  -12.12298 23.08904  1.000 10.29173  ? 1186 ARG A NH2   1 
ATOM   1478 N N     . ARG A 1 181 ? 28.33672  -16.09870 16.23636  1.000 8.66826   ? 1187 ARG A N     1 
ATOM   1479 C CA    . ARG A 1 181 ? 29.53008  -16.86498 15.89453  1.000 8.89593   ? 1187 ARG A CA    1 
ATOM   1480 C C     . ARG A 1 181 ? 30.43877  -16.07499 14.94808  1.000 8.79445   ? 1187 ARG A C     1 
ATOM   1481 O O     . ARG A 1 181 ? 31.66898  -16.11496 15.07060  1.000 9.41896   ? 1187 ARG A O     1 
ATOM   1482 C CB    . ARG A 1 181 ? 29.12094  -18.21110 15.29629  1.000 8.76504   ? 1187 ARG A CB    1 
ATOM   1483 C CG    . ARG A 1 181 ? 30.26704  -19.09506 14.87350  1.000 9.15203   ? 1187 ARG A CG    1 
ATOM   1484 C CD    . ARG A 1 181 ? 29.78073  -20.49385 14.59662  1.000 8.81367   ? 1187 ARG A CD    1 
ATOM   1485 N NE    . ARG A 1 181 ? 30.82101  -21.40571 14.14175  1.000 9.18020   ? 1187 ARG A NE    1 
ATOM   1486 C CZ    . ARG A 1 181 ? 31.62831  -22.08946 14.94113  1.000 9.08103   ? 1187 ARG A CZ    1 
ATOM   1487 N NH1   . ARG A 1 181 ? 31.60267  -21.93336 16.26116  1.000 9.45676   ? 1187 ARG A NH1   1 
ATOM   1488 N NH2   . ARG A 1 181 ? 32.48095  -22.95558 14.40421  1.000 9.97654   ? 1187 ARG A NH2   1 
ATOM   1489 N N     . MET A 1 182 ? 29.84773  -15.35131 13.99788  1.000 8.94684   ? 1188 MET A N     1 
ATOM   1490 C CA    . MET A 1 182 ? 30.62086  -14.59048 13.01352  1.000 9.67878   ? 1188 MET A CA    1 
ATOM   1491 C C     . MET A 1 182 ? 31.31447  -13.40286 13.66267  1.000 9.48242   ? 1188 MET A C     1 
ATOM   1492 O O     . MET A 1 182 ? 32.45703  -13.07649 13.31185  1.000 10.07565  ? 1188 MET A O     1 
ATOM   1493 C CB    . MET A 1 182 ? 29.59689  -14.09325 12.00308  1.000 10.06277  ? 1188 MET A CB    1 
ATOM   1494 C CG    . MET A 1 182 ? 29.24990  -15.14451 10.99940  1.000 10.05143  ? 1188 MET A CG    1 
ATOM   1495 S SD    . MET A 1 182 ? 27.96357  -14.56486 9.90094   1.000 10.74995  ? 1188 MET A SD    1 
ATOM   1496 C CE    . MET A 1 182 ? 27.58201  -16.13738 9.11451   1.000 12.38931  ? 1188 MET A CE    1 
ATOM   1497 N N     . PHE A 1 183 ? 30.64258  -12.73709 14.59768  1.000 9.37816   ? 1189 PHE A N     1 
ATOM   1498 C CA    . PHE A 1 183 ? 31.08669  -11.42462 15.05496  1.000 10.08065  ? 1189 PHE A CA    1 
ATOM   1499 C C     . PHE A 1 183 ? 31.34969  -11.31942 16.54415  1.000 10.09616  ? 1189 PHE A C     1 
ATOM   1500 O O     . PHE A 1 183 ? 32.26323  -10.57734 16.93078  1.000 11.76622  ? 1189 PHE A O     1 
ATOM   1501 C CB    . PHE A 1 183 ? 30.06648  -10.35508 14.66518  1.000 10.36543  ? 1189 PHE A CB    1 
ATOM   1502 C CG    . PHE A 1 183 ? 29.91549  -10.20625 13.18252  1.000 10.02856  ? 1189 PHE A CG    1 
ATOM   1503 C CD1   . PHE A 1 183 ? 31.02445  -9.99519  12.37375  1.000 10.57591  ? 1189 PHE A CD1   1 
ATOM   1504 C CD2   . PHE A 1 183 ? 28.67624  -10.33585 12.58632  1.000 11.02391  ? 1189 PHE A CD2   1 
ATOM   1505 C CE1   . PHE A 1 183 ? 30.89248  -9.87764  11.00187  1.000 10.64578  ? 1189 PHE A CE1   1 
ATOM   1506 C CE2   . PHE A 1 183 ? 28.54062  -10.22601 11.21123  1.000 11.75828  ? 1189 PHE A CE2   1 
ATOM   1507 C CZ    . PHE A 1 183 ? 29.65252  -9.99422  10.42206  1.000 11.34078  ? 1189 PHE A CZ    1 
ATOM   1508 N N     . MET A 1 184 ? 30.58224  -12.00935 17.39368  1.000 9.80306   ? 1190 MET A N     1 
ATOM   1509 C CA    . MET A 1 184 ? 30.65316  -11.65542 18.80656  1.000 10.08787  ? 1190 MET A CA    1 
ATOM   1510 C C     . MET A 1 184 ? 31.63946  -12.53285 19.56950  1.000 10.21248  ? 1190 MET A C     1 
ATOM   1511 O O     . MET A 1 184 ? 32.33135  -12.03589 20.46047  1.000 10.96312  ? 1190 MET A O     1 
ATOM   1512 C CB    . MET A 1 184 ? 29.25593  -11.62430 19.46446  1.000 12.15483  ? 1190 MET A CB    1 
ATOM   1513 C CG    . MET A 1 184 ? 29.21770  -11.46421 20.97304  1.000 11.31873  ? 1190 MET A CG    1 
ATOM   1514 S SD    . MET A 1 184 ? 27.61040  -11.75989 21.71550  1.000 11.02643  ? 1190 MET A SD    1 
ATOM   1515 C CE    . MET A 1 184 ? 26.68959  -10.39290 21.01590  1.000 12.32445  ? 1190 MET A CE    1 
ATOM   1516 N N     . GLU A 1 185 ? 31.74004  -13.81360 19.22800  1.000 9.38112   ? 1191 GLU A N     1 
ATOM   1517 C CA    . GLU A 1 185 ? 32.44768  -14.79151 20.03774  1.000 9.62637   ? 1191 GLU A CA    1 
ATOM   1518 C C     . GLU A 1 185 ? 33.86893  -15.00944 19.53351  1.000 9.70700   ? 1191 GLU A C     1 
ATOM   1519 O O     . GLU A 1 185 ? 34.13280  -14.96902 18.33296  1.000 10.50127  ? 1191 GLU A O     1 
ATOM   1520 C CB    . GLU A 1 185 ? 31.71471  -16.12981 20.01522  1.000 9.41889   ? 1191 GLU A CB    1 
ATOM   1521 C CG    . GLU A 1 185 ? 30.34401  -16.07689 20.63289  1.000 9.25501   ? 1191 GLU A CG    1 
ATOM   1522 C CD    . GLU A 1 185 ? 29.59748  -17.39482 20.55557  1.000 8.82689   ? 1191 GLU A CD    1 
ATOM   1523 O OE1   . GLU A 1 185 ? 29.85995  -18.18873 19.61657  1.000 9.62919   ? 1191 GLU A OE1   1 
ATOM   1524 O OE2   . GLU A 1 185 ? 28.71607  -17.62044 21.42601  1.000 9.29688   ? 1191 GLU A OE2   1 
ATOM   1525 N N     . ASP A 1 186 ? 34.79034  -15.27520 20.45680  1.000 10.35719  ? 1192 ASP A N     1 
ATOM   1526 C CA    . ASP A 1 186 ? 36.17763  -15.54261 20.07669  1.000 10.54313  ? 1192 ASP A CA    1 
ATOM   1527 C C     . ASP A 1 186 ? 36.33161  -17.01659 19.72440  1.000 10.88999  ? 1192 ASP A C     1 
ATOM   1528 O O     . ASP A 1 186 ? 36.62871  -17.85806 20.57784  1.000 12.08136  ? 1192 ASP A O     1 
ATOM   1529 C CB    . ASP A 1 186 ? 37.12843  -15.13380 21.19263  1.000 12.25170  ? 1192 ASP A CB    1 
ATOM   1530 C CG    . ASP A 1 186 ? 38.58056  -15.24054 20.78763  1.000 13.71421  ? 1192 ASP A CG    1 
ATOM   1531 O OD1   . ASP A 1 186 ? 38.87284  -15.47512 19.59973  1.000 14.45398  ? 1192 ASP A OD1   1 
ATOM   1532 O OD2   . ASP A 1 186 ? 39.44281  -15.11027 21.67070  1.000 15.14127  ? 1192 ASP A OD2   1 
ATOM   1533 N N     . VAL A 1 187 ? 36.12075  -17.33321 18.45091  1.000 10.75830  ? 1193 VAL A N     1 
ATOM   1534 C CA    . VAL A 1 187 ? 36.20425  -18.70359 17.95458  1.000 11.40563  ? 1193 VAL A CA    1 
ATOM   1535 C C     . VAL A 1 187 ? 37.42949  -18.76622 17.05463  1.000 11.55796  ? 1193 VAL A C     1 
ATOM   1536 O O     . VAL A 1 187 ? 37.35299  -18.38441 15.87573  1.000 11.08606  ? 1193 VAL A O     1 
ATOM   1537 C CB    . VAL A 1 187 ? 34.92316  -19.11588 17.20696  1.000 11.09065  ? 1193 VAL A CB    1 
ATOM   1538 C CG1   . VAL A 1 187 ? 35.03864  -20.54934 16.73585  1.000 11.53506  ? 1193 VAL A CG1   1 
ATOM   1539 C CG2   . VAL A 1 187 ? 33.69977  -18.93290 18.10389  1.000 13.03879  ? 1193 VAL A CG2   1 
ATOM   1540 N N     . PRO A 1 188 ? 38.57694  -19.21746 17.55734  1.000 12.74349  ? 1194 PRO A N     1 
ATOM   1541 C CA    . PRO A 1 188 ? 39.80781  -19.06118 16.76604  1.000 14.28013  ? 1194 PRO A CA    1 
ATOM   1542 C C     . PRO A 1 188 ? 39.81484  -19.80428 15.45421  1.000 13.53793  ? 1194 PRO A C     1 
ATOM   1543 O O     . PRO A 1 188 ? 40.52808  -19.38687 14.53299  1.000 15.22268  ? 1194 PRO A O     1 
ATOM   1544 C CB    . PRO A 1 188 ? 40.91380  -19.52720 17.73027  1.000 15.98581  ? 1194 PRO A CB    1 
ATOM   1545 C CG    . PRO A 1 188 ? 40.27044  -19.41206 19.08650  1.000 17.21827  ? 1194 PRO A CG    1 
ATOM   1546 C CD    . PRO A 1 188 ? 38.87389  -19.88241 18.83874  1.000 15.59280  ? 1194 PRO A CD    1 
ATOM   1547 N N     . ASN A 1 189 ? 39.06745  -20.88964 15.33473  1.000 13.14121  ? 1195 ASN A N     1 
ATOM   1548 C CA    . ASN A 1 189 ? 39.07753  -21.67135 14.10803  1.000 13.98148  ? 1195 ASN A CA    1 
ATOM   1549 C C     . ASN A 1 189 ? 38.03055  -21.20716 13.09975  1.000 14.30509  ? 1195 ASN A C     1 
ATOM   1550 O O     . ASN A 1 189 ? 37.92361  -21.81679 12.03218  1.000 16.44805  ? 1195 ASN A O     1 
ATOM   1551 C CB    . ASN A 1 189 ? 38.83667  -23.13975 14.44610  1.000 13.99490  ? 1195 ASN A CB    1 
ATOM   1552 C CG    . ASN A 1 189 ? 37.60613  -23.31821 15.30077  1.000 12.81733  ? 1195 ASN A CG    1 
ATOM   1553 O OD1   . ASN A 1 189 ? 37.60176  -22.95296 16.47895  1.000 14.17573  ? 1195 ASN A OD1   1 
ATOM   1554 N ND2   . ASN A 1 189 ? 36.56958  -23.92352 14.74311  1.000 14.26098  ? 1195 ASN A ND2   1 
ATOM   1555 N N     . TYR A 1 190 ? 37.25046  -20.15912 13.40512  1.000 13.12121  ? 1196 TYR A N     1 
ATOM   1556 C CA    . TYR A 1 190 ? 36.29096  -19.58803 12.44743  1.000 12.30064  ? 1196 TYR A CA    1 
ATOM   1557 C C     . TYR A 1 190 ? 36.35561  -18.06446 12.55147  1.000 11.26551  ? 1196 TYR A C     1 
ATOM   1558 O O     . TYR A 1 190 ? 35.67992  -17.45013 13.38335  1.000 11.90067  ? 1196 TYR A O     1 
ATOM   1559 C CB    . TYR A 1 190 ? 34.87182  -20.10475 12.64497  1.000 13.17174  ? 1196 TYR A CB    1 
ATOM   1560 C CG    . TYR A 1 190 ? 33.91039  -19.59834 11.58736  1.000 12.49120  ? 1196 TYR A CG    1 
ATOM   1561 C CD1   . TYR A 1 190 ? 34.03168  -19.98095 10.25220  1.000 12.26847  ? 1196 TYR A CD1   1 
ATOM   1562 C CD2   . TYR A 1 190 ? 32.88983  -18.72194 11.92809  1.000 12.63062  ? 1196 TYR A CD2   1 
ATOM   1563 C CE1   . TYR A 1 190 ? 33.14843  -19.50579 9.28627   1.000 11.59994  ? 1196 TYR A CE1   1 
ATOM   1564 C CE2   . TYR A 1 190 ? 31.99886  -18.25343 10.97682  1.000 11.92411  ? 1196 TYR A CE2   1 
ATOM   1565 C CZ    . TYR A 1 190 ? 32.12917  -18.64589 9.65844   1.000 11.27052  ? 1196 TYR A CZ    1 
ATOM   1566 O OH    . TYR A 1 190 ? 31.23055  -18.16426 8.73386   1.000 11.43628  ? 1196 TYR A OH    1 
ATOM   1567 N N     . ARG A 1 191 ? 37.16382  -17.46411 11.68747  1.000 11.37485  ? 1197 ARG A N     1 
ATOM   1568 C CA    . ARG A 1 191 ? 37.34086  -16.01966 11.62594  1.000 11.88338  ? 1197 ARG A CA    1 
ATOM   1569 C C     . ARG A 1 191 ? 36.64023  -15.54964 10.35936  1.000 12.31520  ? 1197 ARG A C     1 
ATOM   1570 O O     . ARG A 1 191 ? 37.16100  -15.70562 9.25168   1.000 12.59049  ? 1197 ARG A O     1 
ATOM   1571 C CB    . ARG A 1 191 ? 38.81787  -15.65678 11.59890  1.000 13.06048  ? 1197 ARG A CB    1 
ATOM   1572 C CG    . ARG A 1 191 ? 39.59530  -16.13822 12.80846  1.000 13.54351  ? 1197 ARG A CG    1 
ATOM   1573 C CD    . ARG A 1 191 ? 39.01168  -15.60363 14.10240  1.000 13.49861  ? 1197 ARG A CD    1 
ATOM   1574 N NE    . ARG A 1 191 ? 39.98193  -15.71656 15.18863  1.000 13.58925  ? 1197 ARG A NE    1 
ATOM   1575 C CZ    . ARG A 1 191 ? 39.70194  -15.54599 16.47426  1.000 13.08203  ? 1197 ARG A CZ    1 
ATOM   1576 N NH1   . ARG A 1 191 ? 38.47899  -15.24900 16.88156  1.000 12.71488  ? 1197 ARG A NH1   1 
ATOM   1577 N NH2   . ARG A 1 191 ? 40.67493  -15.67213 17.37616  1.000 14.05564  ? 1197 ARG A NH2   1 
ATOM   1578 N N     . PHE A 1 192 ? 35.45066  -14.98532 10.53143  1.000 12.17930  ? 1198 PHE A N     1 
ATOM   1579 C CA    . PHE A 1 192 ? 34.61085  -14.59732 9.41171   1.000 11.79917  ? 1198 PHE A CA    1 
ATOM   1580 C C     . PHE A 1 192 ? 35.07298  -13.26539 8.84072   1.000 12.04555  ? 1198 PHE A C     1 
ATOM   1581 O O     . PHE A 1 192 ? 35.18092  -12.26961 9.56468   1.000 13.86783  ? 1198 PHE A O     1 
ATOM   1582 C CB    . PHE A 1 192 ? 33.15970  -14.47890 9.86400   1.000 11.06072  ? 1198 PHE A CB    1 
ATOM   1583 C CG    . PHE A 1 192 ? 32.23128  -14.10605 8.74826   1.000 10.68069  ? 1198 PHE A CG    1 
ATOM   1584 C CD1   . PHE A 1 192 ? 32.00370  -14.99215 7.70590   1.000 10.64435  ? 1198 PHE A CD1   1 
ATOM   1585 C CD2   . PHE A 1 192 ? 31.61215  -12.86621 8.71319   1.000 10.77580  ? 1198 PHE A CD2   1 
ATOM   1586 C CE1   . PHE A 1 192 ? 31.17257  -14.65232 6.64727   1.000 10.60740  ? 1198 PHE A CE1   1 
ATOM   1587 C CE2   . PHE A 1 192 ? 30.76621  -12.52797 7.65753   1.000 11.13448  ? 1198 PHE A CE2   1 
ATOM   1588 C CZ    . PHE A 1 192 ? 30.54946  -13.42577 6.62872   1.000 10.98945  ? 1198 PHE A CZ    1 
ATOM   1589 N N     . GLY A 1 193 ? 35.33071  -13.24638 7.53603   1.000 12.36676  ? 1199 GLY A N     1 
ATOM   1590 C CA    . GLY A 1 193 ? 35.76072  -12.03425 6.87570   1.000 13.21848  ? 1199 GLY A CA    1 
ATOM   1591 C C     . GLY A 1 193 ? 34.95646  -11.73577 5.63011   1.000 12.45558  ? 1199 GLY A C     1 
ATOM   1592 O O     . GLY A 1 193 ? 35.40004  -10.95864 4.78497   1.000 13.69186  ? 1199 GLY A O     1 
ATOM   1593 N N     . GLY A 1 194 ? 33.77804  -12.32843 5.50255   1.000 11.75145  ? 1200 GLY A N     1 
ATOM   1594 C CA    . GLY A 1 194 ? 32.91485  -12.09887 4.36316   1.000 11.85316  ? 1200 GLY A CA    1 
ATOM   1595 C C     . GLY A 1 194 ? 31.89628  -11.01793 4.63117   1.000 11.12871  ? 1200 GLY A C     1 
ATOM   1596 O O     . GLY A 1 194 ? 32.14725  -10.06367 5.37325   1.000 11.97297  ? 1200 GLY A O     1 
ATOM   1597 N N     . LEU A 1 195 ? 30.72835  -11.16396 4.01037   1.000 10.56786  ? 1201 LEU A N     1 
ATOM   1598 C CA    . LEU A 1 195 ? 29.61165  -10.25437 4.21044   1.000 10.22578  ? 1201 LEU A CA    1 
ATOM   1599 C C     . LEU A 1 195 ? 28.43208  -11.05457 4.73067   1.000 9.68162   ? 1201 LEU A C     1 
ATOM   1600 O O     . LEU A 1 195 ? 28.02993  -12.04834 4.11338   1.000 10.37873  ? 1201 LEU A O     1 
ATOM   1601 C CB    . LEU A 1 195 ? 29.22453  -9.54345  2.91325   1.000 11.42248  ? 1201 LEU A CB    1 
ATOM   1602 C CG    . LEU A 1 195 ? 27.92329  -8.73578  2.94443   1.000 12.72247  ? 1201 LEU A CG    1 
ATOM   1603 C CD1   . LEU A 1 195 ? 28.01077  -7.56800  3.90953   1.000 13.68880  ? 1201 LEU A CD1   1 
ATOM   1604 C CD2   . LEU A 1 195 ? 27.57737  -8.23507  1.54962   1.000 14.27288  ? 1201 LEU A CD2   1 
ATOM   1605 N N     . ALA A 1 196 ? 27.89680  -10.63269 5.87181   1.000 9.51230   ? 1202 ALA A N     1 
ATOM   1606 C CA    . ALA A 1 196 ? 26.65507  -11.15546 6.40951   1.000 9.24769   ? 1202 ALA A CA    1 
ATOM   1607 C C     . ALA A 1 196 ? 25.62594  -10.04262 6.30560   1.000 9.62167   ? 1202 ALA A C     1 
ATOM   1608 O O     . ALA A 1 196 ? 25.88763  -8.91128  6.72900   1.000 10.67060  ? 1202 ALA A O     1 
ATOM   1609 C CB    . ALA A 1 196 ? 26.83403  -11.56560 7.86819   1.000 10.33251  ? 1202 ALA A CB    1 
ATOM   1610 N N     . TRP A 1 197 ? 24.47560  -10.34600 5.71575   1.000 9.17855   ? 1203 TRP A N     1 
ATOM   1611 C CA    . TRP A 1 197 ? 23.46842  -9.32705  5.45385   1.000 9.61368   ? 1203 TRP A CA    1 
ATOM   1612 C C     . TRP A 1 197 ? 22.14002  -9.84517  5.96917   1.000 9.62014   ? 1203 TRP A C     1 
ATOM   1613 O O     . TRP A 1 197 ? 21.57756  -10.78723 5.40232   1.000 10.08168  ? 1203 TRP A O     1 
ATOM   1614 C CB    . TRP A 1 197 ? 23.39439  -9.02651  3.96279   1.000 10.33068  ? 1203 TRP A CB    1 
ATOM   1615 C CG    . TRP A 1 197 ? 22.64794  -7.79182  3.59196   1.000 10.64602  ? 1203 TRP A CG    1 
ATOM   1616 C CD1   . TRP A 1 197 ? 21.75454  -7.07977  4.35230   1.000 11.35759  ? 1203 TRP A CD1   1 
ATOM   1617 C CD2   . TRP A 1 197 ? 22.73148  -7.12445  2.34039   1.000 11.09354  ? 1203 TRP A CD2   1 
ATOM   1618 N NE1   . TRP A 1 197 ? 21.29060  -5.99669  3.64166   1.000 12.17371  ? 1203 TRP A NE1   1 
ATOM   1619 C CE2   . TRP A 1 197 ? 21.87328  -6.00788  2.40056   1.000 12.06783  ? 1203 TRP A CE2   1 
ATOM   1620 C CE3   . TRP A 1 197 ? 23.45716  -7.35977  1.17003   1.000 12.36539  ? 1203 TRP A CE3   1 
ATOM   1621 C CZ2   . TRP A 1 197 ? 21.71953  -5.12709  1.32370   1.000 12.93141  ? 1203 TRP A CZ2   1 
ATOM   1622 C CZ3   . TRP A 1 197 ? 23.30981  -6.48721  0.11346   1.000 13.11967  ? 1203 TRP A CZ3   1 
ATOM   1623 C CH2   . TRP A 1 197 ? 22.44242  -5.38645  0.19048   1.000 13.24236  ? 1203 TRP A CH2   1 
ATOM   1624 N N     . LEU A 1 198 ? 21.64902  -9.24082  7.04807   1.000 9.48713   ? 1204 LEU A N     1 
ATOM   1625 C CA    . LEU A 1 198 ? 20.39678  -9.64178  7.66546   1.000 9.99119   ? 1204 LEU A CA    1 
ATOM   1626 C C     . LEU A 1 198 ? 19.25654  -8.73914  7.21543   1.000 10.32079  ? 1204 LEU A C     1 
ATOM   1627 O O     . LEU A 1 198 ? 19.34088  -7.51104  7.34503   1.000 11.10355  ? 1204 LEU A O     1 
ATOM   1628 C CB    . LEU A 1 198 ? 20.50905  -9.59574  9.19231   1.000 10.17358  ? 1204 LEU A CB    1 
ATOM   1629 C CG    . LEU A 1 198 ? 19.23094  -9.90562  9.97436   1.000 10.77851  ? 1204 LEU A CG    1 
ATOM   1630 C CD1   . LEU A 1 198 ? 18.76154  -11.32281 9.74605   1.000 11.14534  ? 1204 LEU A CD1   1 
ATOM   1631 C CD2   . LEU A 1 198 ? 19.44546  -9.65016  11.45543  1.000 11.58291  ? 1204 LEU A CD2   1 
ATOM   1632 N N     A PHE A 1 199 ? 18.19386  -9.35247  6.69912   0.902 10.36233  ? 1205 PHE A N     1 
ATOM   1633 N N     B PHE A 1 199 ? 18.19569  -9.35962  6.70441   0.098 10.80591  ? 1205 PHE A N     1 
ATOM   1634 C CA    A PHE A 1 199 ? 16.92805  -8.69038  6.42529   0.902 11.52750  ? 1205 PHE A CA    1 
ATOM   1635 C CA    B PHE A 1 199 ? 16.92802  -8.70708  6.41337   0.098 11.35377  ? 1205 PHE A CA    1 
ATOM   1636 C C     A PHE A 1 199 ? 15.90491  -9.26010  7.39481   0.902 12.07787  ? 1205 PHE A C     1 
ATOM   1637 C C     B PHE A 1 199 ? 15.89488  -9.26684  7.38143   0.098 11.72004  ? 1205 PHE A C     1 
ATOM   1638 O O     A PHE A 1 199 ? 15.76619  -10.48185 7.50742   0.902 12.07545  ? 1205 PHE A O     1 
ATOM   1639 O O     B PHE A 1 199 ? 15.74402  -10.48852 7.48840   0.098 11.70211  ? 1205 PHE A O     1 
ATOM   1640 C CB    A PHE A 1 199 ? 16.45699  -9.00935  5.00820   0.902 11.62569  ? 1205 PHE A CB    1 
ATOM   1641 C CB    B PHE A 1 199 ? 16.47663  -9.03856  4.98978   0.098 11.51962  ? 1205 PHE A CB    1 
ATOM   1642 C CG    A PHE A 1 199 ? 17.24080  -8.32519  3.92217   0.902 11.67110  ? 1205 PHE A CG    1 
ATOM   1643 C CG    B PHE A 1 199 ? 17.33081  -8.43280  3.91025   0.098 11.55341  ? 1205 PHE A CG    1 
ATOM   1644 C CD1   A PHE A 1 199 ? 18.45433  -8.83149  3.47801   0.902 11.73979  ? 1205 PHE A CD1   1 
ATOM   1645 C CD1   B PHE A 1 199 ? 18.56119  -8.98296  3.58769   0.098 11.56319  ? 1205 PHE A CD1   1 
ATOM   1646 C CD2   A PHE A 1 199 ? 16.73963  -7.18077  3.32072   0.902 13.74194  ? 1205 PHE A CD2   1 
ATOM   1647 C CD2   B PHE A 1 199 ? 16.88773  -7.33233  3.19484   0.098 11.91851  ? 1205 PHE A CD2   1 
ATOM   1648 C CE1   A PHE A 1 199 ? 19.15541  -8.19509  2.46203   0.902 12.64513  ? 1205 PHE A CE1   1 
ATOM   1649 C CE1   B PHE A 1 199 ? 19.33891  -8.43775  2.58480   0.098 11.83500  ? 1205 PHE A CE1   1 
ATOM   1650 C CE2   A PHE A 1 199 ? 17.43877  -6.53749  2.31341   0.902 13.92924  ? 1205 PHE A CE2   1 
ATOM   1651 C CE2   B PHE A 1 199 ? 17.66382  -6.78095  2.19113   0.098 12.07312  ? 1205 PHE A CE2   1 
ATOM   1652 C CZ    A PHE A 1 199 ? 18.64455  -7.04770  1.88041   0.902 13.86133  ? 1205 PHE A CZ    1 
ATOM   1653 C CZ    B PHE A 1 199 ? 18.89050  -7.33560  1.88664   0.098 12.10795  ? 1205 PHE A CZ    1 
ATOM   1654 N N     . LEU A 1 200 ? 15.17877  -8.38545  8.07713   1.000 12.08500  ? 1206 LEU A N     1 
ATOM   1655 C CA    . LEU A 1 200 ? 14.19807  -8.80615  9.07270   1.000 12.88204  ? 1206 LEU A CA    1 
ATOM   1656 C C     . LEU A 1 200 ? 12.86900  -8.10534  8.83807   1.000 13.85922  ? 1206 LEU A C     1 
ATOM   1657 O O     . LEU A 1 200 ? 12.80034  -6.87210  8.86301   1.000 14.38278  ? 1206 LEU A O     1 
ATOM   1658 C CB    . LEU A 1 200 ? 14.70371  -8.50244  10.48246  1.000 12.88933  ? 1206 LEU A CB    1 
ATOM   1659 C CG    . LEU A 1 200 ? 13.74086  -8.86221  11.61183  1.000 14.56183  ? 1206 LEU A CG    1 
ATOM   1660 C CD1   . LEU A 1 200 ? 13.40555  -10.34745 11.64249  1.000 14.87267  ? 1206 LEU A CD1   1 
ATOM   1661 C CD2   . LEU A 1 200 ? 14.30487  -8.41458  12.93260  1.000 16.11625  ? 1206 LEU A CD2   1 
ATOM   1662 N N     . GLY A 1 201 ? 11.81174  -8.88722  8.63978   1.000 14.38612  ? 1207 GLY A N     1 
ATOM   1663 C CA    . GLY A 1 201 ? 10.45815  -8.36347  8.54829   1.000 15.62691  ? 1207 GLY A CA    1 
ATOM   1664 C C     . GLY A 1 201 ? 9.66666   -8.69104  9.80478   1.000 16.28510  ? 1207 GLY A C     1 
ATOM   1665 O O     . GLY A 1 201 ? 9.60992   -9.84719  10.22721  1.000 16.05891  ? 1207 GLY A O     1 
ATOM   1666 N N     . VAL A 1 202 ? 9.08444   -7.65450  10.40707  1.000 16.81695  ? 1208 VAL A N     1 
ATOM   1667 C CA    . VAL A 1 202 ? 8.20968   -7.79030  11.56514  1.000 17.35615  ? 1208 VAL A CA    1 
ATOM   1668 C C     . VAL A 1 202 ? 7.04922   -6.81364  11.40070  1.000 19.40956  ? 1208 VAL A C     1 
ATOM   1669 O O     . VAL A 1 202 ? 7.01054   -6.01966  10.45906  1.000 21.69920  ? 1208 VAL A O     1 
ATOM   1670 C CB    . VAL A 1 202 ? 8.94817   -7.55638  12.90168  1.000 16.83355  ? 1208 VAL A CB    1 
ATOM   1671 C CG1   . VAL A 1 202 ? 10.01818  -8.62071  13.12701  1.000 16.09060  ? 1208 VAL A CG1   1 
ATOM   1672 C CG2   . VAL A 1 202 ? 9.52111   -6.16129  12.96473  1.000 16.98723  ? 1208 VAL A CG2   1 
ATOM   1673 N N     . ALA A 1 203 ? 6.09904   -6.86126  12.33668  1.000 20.27223  ? 1209 ALA A N     1 
ATOM   1674 C CA    . ALA A 1 203 ? 4.87559   -6.08043  12.18027  1.000 21.36990  ? 1209 ALA A CA    1 
ATOM   1675 C C     . ALA A 1 203 ? 5.09887   -4.59491  12.43908  1.000 22.16801  ? 1209 ALA A C     1 
ATOM   1676 O O     . ALA A 1 203 ? 4.49832   -3.75094  11.76030  1.000 24.73821  ? 1209 ALA A O     1 
ATOM   1677 C CB    . ALA A 1 203 ? 3.78477   -6.63014  13.09848  1.000 21.76577  ? 1209 ALA A CB    1 
ATOM   1678 N N     . ASN A 1 204 ? 5.93240   -4.25527  13.41797  1.000 21.49323  ? 1210 ASN A N     1 
ATOM   1679 C CA    . ASN A 1 204 ? 6.15768   -2.86432  13.79311  1.000 21.49001  ? 1210 ASN A CA    1 
ATOM   1680 C C     . ASN A 1 204 ? 7.43068   -2.79576  14.62901  1.000 20.01626  ? 1210 ASN A C     1 
ATOM   1681 O O     . ASN A 1 204 ? 8.04554   -3.82047  14.93920  1.000 19.61867  ? 1210 ASN A O     1 
ATOM   1682 C CB    . ASN A 1 204 ? 4.93302   -2.25365  14.49287  1.000 22.05942  ? 1210 ASN A CB    1 
ATOM   1683 C CG    . ASN A 1 204 ? 4.48109   -3.04673  15.70875  1.000 21.72472  ? 1210 ASN A CG    1 
ATOM   1684 O OD1   . ASN A 1 204 ? 5.27560   -3.70951  16.36804  1.000 21.54700  ? 1210 ASN A OD1   1 
ATOM   1685 N ND2   . ASN A 1 204 ? 3.19695   -2.95622  16.02474  1.000 22.63707  ? 1210 ASN A ND2   1 
ATOM   1686 N N     . SER A 1 205 ? 7.83093   -1.57172  14.98387  1.000 19.85343  ? 1211 SER A N     1 
ATOM   1687 C CA    . SER A 1 205 ? 9.08117   -1.38807  15.71752  1.000 19.99917  ? 1211 SER A CA    1 
ATOM   1688 C C     . SER A 1 205 ? 9.07214   -2.13916  17.04379  1.000 18.77013  ? 1211 SER A C     1 
ATOM   1689 O O     . SER A 1 205 ? 10.09729  -2.69361  17.45989  1.000 19.11514  ? 1211 SER A O     1 
ATOM   1690 C CB    . SER A 1 205 ? 9.34418   0.09655   15.95160  1.000 22.66085  ? 1211 SER A CB    1 
ATOM   1691 O OG    . SER A 1 205 ? 10.57163  0.29423   16.62201  1.000 25.89531  ? 1211 SER A OG    1 
ATOM   1692 N N     . ASP A 1 206 ? 7.92156   -2.16899  17.72105  1.000 18.16118  ? 1212 ASP A N     1 
ATOM   1693 C CA    . ASP A 1 206 ? 7.80872   -2.88675  18.98640  1.000 17.20485  ? 1212 ASP A CA    1 
ATOM   1694 C C     . ASP A 1 206 ? 7.92443   -4.39526  18.81665  1.000 16.38124  ? 1212 ASP A C     1 
ATOM   1695 O O     . ASP A 1 206 ? 8.11963   -5.10319  19.81119  1.000 15.85388  ? 1212 ASP A O     1 
ATOM   1696 C CB    . ASP A 1 206 ? 6.48232   -2.55423  19.67887  1.000 18.39134  ? 1212 ASP A CB    1 
ATOM   1697 C CG    . ASP A 1 206 ? 6.56540   -1.31295  20.54693  1.000 20.57729  ? 1212 ASP A CG    1 
ATOM   1698 O OD1   . ASP A 1 206 ? 7.58431   -0.59592  20.47774  1.000 22.37842  ? 1212 ASP A OD1   1 
ATOM   1699 O OD2   . ASP A 1 206 ? 5.60425   -1.05044  21.29900  1.000 21.42399  ? 1212 ASP A OD2   1 
ATOM   1700 N N     . SER A 1 207 ? 7.80181   -4.90204  17.59358  1.000 15.96544  ? 1213 SER A N     1 
ATOM   1701 C CA    . SER A 1 207 ? 7.92384   -6.32537  17.31787  1.000 15.36126  ? 1213 SER A CA    1 
ATOM   1702 C C     . SER A 1 207 ? 9.32755   -6.72921  16.90561  1.000 15.30798  ? 1213 SER A C     1 
ATOM   1703 O O     . SER A 1 207 ? 9.55028   -7.90473  16.60726  1.000 14.63226  ? 1213 SER A O     1 
ATOM   1704 C CB    . SER A 1 207 ? 6.93731   -6.74410  16.22388  1.000 16.89423  ? 1213 SER A CB    1 
ATOM   1705 O OG    . SER A 1 207 ? 5.60373   -6.42819  16.59270  1.000 18.18268  ? 1213 SER A OG    1 
ATOM   1706 N N     . LEU A 1 208 ? 10.26613  -5.79054  16.85843  1.000 14.99187  ? 1214 LEU A N     1 
ATOM   1707 C CA    . LEU A 1 208 ? 11.63787  -6.14533  16.53398  1.000 14.38196  ? 1214 LEU A CA    1 
ATOM   1708 C C     . LEU A 1 208 ? 12.21122  -7.07626  17.59540  1.000 13.30709  ? 1214 LEU A C     1 
ATOM   1709 O O     . LEU A 1 208 ? 11.81906  -7.04810  18.76657  1.000 13.27425  ? 1214 LEU A O     1 
ATOM   1710 C CB    . LEU A 1 208 ? 12.50049  -4.89214  16.39415  1.000 15.17173  ? 1214 LEU A CB    1 
ATOM   1711 C CG    . LEU A 1 208 ? 12.28799  -4.11178  15.09423  1.000 16.61597  ? 1214 LEU A CG    1 
ATOM   1712 C CD1   . LEU A 1 208 ? 12.91758  -2.73599  15.19111  1.000 17.30595  ? 1214 LEU A CD1   1 
ATOM   1713 C CD2   . LEU A 1 208 ? 12.84769  -4.87979  13.90432  1.000 17.08818  ? 1214 LEU A CD2   1 
ATOM   1714 N N     . LEU A 1 209 ? 13.13626  -7.92279  17.15384  1.000 12.66264  ? 1215 LEU A N     1 
ATOM   1715 C CA    . LEU A 1 209 ? 13.71850  -8.97374  17.97576  1.000 11.83302  ? 1215 LEU A CA    1 
ATOM   1716 C C     . LEU A 1 209 ? 15.23149  -8.82700  17.92021  1.000 11.40076  ? 1215 LEU A C     1 
ATOM   1717 O O     . LEU A 1 209 ? 15.82856  -8.93781  16.84221  1.000 11.54231  ? 1215 LEU A O     1 
ATOM   1718 C CB    . LEU A 1 209 ? 13.30225  -10.35751 17.46240  1.000 11.43690  ? 1215 LEU A CB    1 
ATOM   1719 C CG    . LEU A 1 209 ? 11.80368  -10.60907 17.28991  1.000 12.13069  ? 1215 LEU A CG    1 
ATOM   1720 C CD1   . LEU A 1 209 ? 11.55583  -11.94728 16.62318  1.000 12.56674  ? 1215 LEU A CD1   1 
ATOM   1721 C CD2   . LEU A 1 209 ? 11.06164  -10.50528 18.62081  1.000 13.05966  ? 1215 LEU A CD2   1 
ATOM   1722 N N     . TYR A 1 210 ? 15.85020  -8.57689  19.07633  1.000 11.36947  ? 1216 TYR A N     1 
ATOM   1723 C CA    . TYR A 1 210 ? 17.30969  -8.48571  19.18432  1.000 11.06480  ? 1216 TYR A CA    1 
ATOM   1724 C C     . TYR A 1 210 ? 17.88763  -7.30122  18.41089  1.000 11.17260  ? 1216 TYR A C     1 
ATOM   1725 O O     . TYR A 1 210 ? 19.04681  -7.33908  17.98913  1.000 11.16560  ? 1216 TYR A O     1 
ATOM   1726 C CB    . TYR A 1 210 ? 18.00608  -9.78187  18.76403  1.000 10.95910  ? 1216 TYR A CB    1 
ATOM   1727 C CG    . TYR A 1 210 ? 17.35444  -11.05840 19.26048  1.000 10.32837  ? 1216 TYR A CG    1 
ATOM   1728 C CD1   . TYR A 1 210 ? 17.40420  -11.41846 20.60764  1.000 10.30030  ? 1216 TYR A CD1   1 
ATOM   1729 C CD2   . TYR A 1 210 ? 16.67906  -11.89909 18.38059  1.000 9.95787   ? 1216 TYR A CD2   1 
ATOM   1730 C CE1   . TYR A 1 210 ? 16.82010  -12.59550 21.05763  1.000 9.87315   ? 1216 TYR A CE1   1 
ATOM   1731 C CE2   . TYR A 1 210 ? 16.09069  -13.06779 18.82294  1.000 10.37856  ? 1216 TYR A CE2   1 
ATOM   1732 C CZ    . TYR A 1 210 ? 16.16215  -13.41763 20.15734  1.000 10.04545  ? 1216 TYR A CZ    1 
ATOM   1733 O OH    . TYR A 1 210 ? 15.58671  -14.59975 20.54223  1.000 10.45350  ? 1216 TYR A OH    1 
ATOM   1734 N N     . ASP A 1 211 ? 17.09914  -6.23571  18.22346  1.000 11.59641  ? 1217 ASP A N     1 
ATOM   1735 C CA    . ASP A 1 211 ? 17.52601  -5.14229  17.35195  1.000 12.01177  ? 1217 ASP A CA    1 
ATOM   1736 C C     . ASP A 1 211 ? 18.81109  -4.48280  17.84278  1.000 12.24418  ? 1217 ASP A C     1 
ATOM   1737 O O     . ASP A 1 211 ? 19.66790  -4.10333  17.03413  1.000 13.47871  ? 1217 ASP A O     1 
ATOM   1738 C CB    . ASP A 1 211 ? 16.40531  -4.11147  17.25130  1.000 13.43352  ? 1217 ASP A CB    1 
ATOM   1739 C CG    . ASP A 1 211 ? 16.73219  -2.97751  16.30584  1.000 14.81008  ? 1217 ASP A CG    1 
ATOM   1740 O OD1   . ASP A 1 211 ? 17.01941  -3.24781  15.12176  1.000 14.98697  ? 1217 ASP A OD1   1 
ATOM   1741 O OD2   . ASP A 1 211 ? 16.69678  -1.81626  16.75450  1.000 17.10512  ? 1217 ASP A OD2   1 
ATOM   1742 N N     . GLU A 1 212 ? 18.95485  -4.30990  19.16034  1.000 12.76378  ? 1218 GLU A N     1 
ATOM   1743 C CA    . GLU A 1 212 ? 20.15464  -3.66505  19.68174  1.000 13.74600  ? 1218 GLU A CA    1 
ATOM   1744 C C     . GLU A 1 212 ? 21.39928  -4.48219  19.36726  1.000 13.00887  ? 1218 GLU A C     1 
ATOM   1745 O O     . GLU A 1 212 ? 22.45586  -3.91867  19.05403  1.000 13.14897  ? 1218 GLU A O     1 
ATOM   1746 C CB    . GLU A 1 212 ? 20.01520  -3.44799  21.18652  1.000 15.78007  ? 1218 GLU A CB    1 
ATOM   1747 C CG    . GLU A 1 212 ? 21.22045  -2.81803  21.85676  1.000 83.82431  ? 1218 GLU A CG    1 
ATOM   1748 C CD    . GLU A 1 212 ? 20.87558  -2.20442  23.19918  1.000 127.67937 ? 1218 GLU A CD    1 
ATOM   1749 O OE1   . GLU A 1 212 ? 21.61651  -1.30844  23.65417  1.000 131.02467 ? 1218 GLU A OE1   1 
ATOM   1750 O OE2   . GLU A 1 212 ? 19.85930  -2.61664  23.79764  1.000 129.98520 ? 1218 GLU A OE2   1 
ATOM   1751 N N     . GLU A 1 213 ? 21.29194  -5.81037  19.44941  1.000 12.10335  ? 1219 GLU A N     1 
ATOM   1752 C CA    . GLU A 1 213 ? 22.41762  -6.67511  19.11508  1.000 11.71931  ? 1219 GLU A CA    1 
ATOM   1753 C C     . GLU A 1 213 ? 22.82241  -6.50637  17.65670  1.000 11.77442  ? 1219 GLU A C     1 
ATOM   1754 O O     . GLU A 1 213 ? 24.00778  -6.33693  17.33782  1.000 12.21059  ? 1219 GLU A O     1 
ATOM   1755 C CB    . GLU A 1 213 ? 22.05277  -8.12605  19.41487  1.000 11.63496  ? 1219 GLU A CB    1 
ATOM   1756 C CG    . GLU A 1 213 ? 23.19226  -9.09918  19.19621  1.000 11.44458  ? 1219 GLU A CG    1 
ATOM   1757 C CD    . GLU A 1 213 ? 23.04096  -10.34599 20.04127  1.000 10.80204  ? 1219 GLU A CD    1 
ATOM   1758 O OE1   . GLU A 1 213 ? 22.97217  -10.17244 21.28078  1.000 11.54599  ? 1219 GLU A OE1   1 
ATOM   1759 O OE2   . GLU A 1 213 ? 23.04320  -11.47702 19.49662  1.000 10.63883  ? 1219 GLU A OE2   1 
ATOM   1760 N N     . PHE A 1 214 ? 21.84991  -6.55231  16.74899  1.000 12.15670  ? 1220 PHE A N     1 
ATOM   1761 C CA    . PHE A 1 214 ? 22.17973  -6.43494  15.33421  1.000 12.64147  ? 1220 PHE A CA    1 
ATOM   1762 C C     . PHE A 1 214 ? 22.70680  -5.04426  15.00861  1.000 13.29971  ? 1220 PHE A C     1 
ATOM   1763 O O     . PHE A 1 214 ? 23.66042  -4.89943  14.23201  1.000 14.44427  ? 1220 PHE A O     1 
ATOM   1764 C CB    . PHE A 1 214 ? 20.95760  -6.79102  14.49481  1.000 12.43800  ? 1220 PHE A CB    1 
ATOM   1765 C CG    . PHE A 1 214 ? 20.44081  -8.18046  14.75709  1.000 11.93246  ? 1220 PHE A CG    1 
ATOM   1766 C CD1   . PHE A 1 214 ? 21.32381  -9.23129  14.97704  1.000 12.70940  ? 1220 PHE A CD1   1 
ATOM   1767 C CD2   . PHE A 1 214 ? 19.07834  -8.42729  14.82460  1.000 12.67082  ? 1220 PHE A CD2   1 
ATOM   1768 C CE1   . PHE A 1 214 ? 20.85466  -10.50720 15.23282  1.000 12.34137  ? 1220 PHE A CE1   1 
ATOM   1769 C CE2   . PHE A 1 214 ? 18.60070  -9.70648  15.07619  1.000 12.99967  ? 1220 PHE A CE2   1 
ATOM   1770 C CZ    . PHE A 1 214 ? 19.48962  -10.74837 15.27292  1.000 12.20694  ? 1220 PHE A CZ    1 
ATOM   1771 N N     . THR A 1 215 ? 22.10576  -4.00666  15.59041  1.000 14.19463  ? 1221 THR A N     1 
ATOM   1772 C CA    . THR A 1 215 ? 22.59051  -2.65861  15.32908  1.000 15.19059  ? 1221 THR A CA    1 
ATOM   1773 C C     . THR A 1 215 ? 24.02833  -2.49484  15.80605  1.000 14.78460  ? 1221 THR A C     1 
ATOM   1774 O O     . THR A 1 215 ? 24.82578  -1.79918  15.16525  1.000 16.40020  ? 1221 THR A O     1 
ATOM   1775 C CB    . THR A 1 215 ? 21.64860  -1.64468  15.97573  1.000 16.92153  ? 1221 THR A CB    1 
ATOM   1776 O OG1   . THR A 1 215 ? 20.36082  -1.73764  15.35312  1.000 18.97115  ? 1221 THR A OG1   1 
ATOM   1777 C CG2   . THR A 1 215 ? 22.17833  -0.23774  15.81306  1.000 19.16170  ? 1221 THR A CG2   1 
ATOM   1778 N N     . SER A 1 216 ? 24.38716  -3.16059  16.90713  1.000 14.59016  ? 1222 SER A N     1 
ATOM   1779 C CA    A SER A 1 216 ? 25.75672  -3.09480  17.40786  0.397 15.47127  ? 1222 SER A CA    1 
ATOM   1780 C CA    B SER A 1 216 ? 25.75815  -3.07178  17.39524  0.283 13.88333  ? 1222 SER A CA    1 
ATOM   1781 C CA    C SER A 1 216 ? 25.75798  -3.08612  17.40357  0.319 14.04418  ? 1222 SER A CA    1 
ATOM   1782 C C     . SER A 1 216 ? 26.74824  -3.64765  16.39007  1.000 13.79486  ? 1222 SER A C     1 
ATOM   1783 O O     . SER A 1 216 ? 27.86297  -3.13367  16.25116  1.000 13.86649  ? 1222 SER A O     1 
ATOM   1784 C CB    A SER A 1 216 ? 25.85493  -3.83139  18.74949  0.397 18.37032  ? 1222 SER A CB    1 
ATOM   1785 C CB    B SER A 1 216 ? 25.88681  -3.75022  18.75791  0.283 13.86261  ? 1222 SER A CB    1 
ATOM   1786 C CB    C SER A 1 216 ? 25.87519  -3.82636  18.73594  0.319 14.35074  ? 1222 SER A CB    1 
ATOM   1787 O OG    A SER A 1 216 ? 26.03018  -5.23458  18.59179  0.397 13.63097  ? 1222 SER A OG    1 
ATOM   1788 O OG    B SER A 1 216 ? 25.08584  -3.08701  19.72036  0.283 18.43400  ? 1222 SER A OG    1 
ATOM   1789 O OG    C SER A 1 216 ? 27.16694  -3.66594  19.29539  0.319 23.44471  ? 1222 SER A OG    1 
ATOM   1790 N N     . TYR A 1 217 ? 26.36289  -4.70311  15.67015  1.000 12.68476  ? 1223 TYR A N     1 
ATOM   1791 C CA    . TYR A 1 217 ? 27.26592  -5.24185  14.66005  1.000 11.95920  ? 1223 TYR A CA    1 
ATOM   1792 C C     . TYR A 1 217 ? 27.53834  -4.23501  13.54789  1.000 12.32798  ? 1223 TYR A C     1 
ATOM   1793 O O     . TYR A 1 217 ? 28.61603  -4.26490  12.94682  1.000 12.64595  ? 1223 TYR A O     1 
ATOM   1794 C CB    . TYR A 1 217 ? 26.70134  -6.51444  14.04130  1.000 11.33207  ? 1223 TYR A CB    1 
ATOM   1795 C CG    . TYR A 1 217 ? 26.52040  -7.69122  14.96857  1.000 10.84644  ? 1223 TYR A CG    1 
ATOM   1796 C CD1   . TYR A 1 217 ? 27.44288  -7.99353  15.97028  1.000 11.22214  ? 1223 TYR A CD1   1 
ATOM   1797 C CD2   . TYR A 1 217 ? 25.41777  -8.51997  14.82109  1.000 10.74546  ? 1223 TYR A CD2   1 
ATOM   1798 C CE1   . TYR A 1 217 ? 27.26108  -9.09588  16.79519  1.000 11.22154  ? 1223 TYR A CE1   1 
ATOM   1799 C CE2   . TYR A 1 217 ? 25.22998  -9.62581  15.63391  1.000 10.47683  ? 1223 TYR A CE2   1 
ATOM   1800 C CZ    . TYR A 1 217 ? 26.15730  -9.91031  16.62362  1.000 9.94760   ? 1223 TYR A CZ    1 
ATOM   1801 O OH    . TYR A 1 217 ? 25.99739  -10.99914 17.44195  1.000 10.73626  ? 1223 TYR A OH    1 
ATOM   1802 N N     . LEU A 1 218 ? 26.57076  -3.36744  13.22490  1.000 12.80906  ? 1224 LEU A N     1 
ATOM   1803 C CA    . LEU A 1 218 ? 26.82424  -2.35170  12.20132  1.000 13.21981  ? 1224 LEU A CA    1 
ATOM   1804 C C     . LEU A 1 218 ? 27.96735  -1.43359  12.60348  1.000 13.81127  ? 1224 LEU A C     1 
ATOM   1805 O O     . LEU A 1 218 ? 28.72196  -0.95654  11.74432  1.000 14.41033  ? 1224 LEU A O     1 
ATOM   1806 C CB    . LEU A 1 218 ? 25.58088  -1.49587  11.97295  1.000 14.28801  ? 1224 LEU A CB    1 
ATOM   1807 C CG    . LEU A 1 218 ? 24.41020  -2.12267  11.21430  1.000 14.32915  ? 1224 LEU A CG    1 
ATOM   1808 C CD1   . LEU A 1 218 ? 23.19615  -1.20017  11.27510  1.000 14.97407  ? 1224 LEU A CD1   1 
ATOM   1809 C CD2   . LEU A 1 218 ? 24.78234  -2.47323  9.76651   1.000 14.26984  ? 1224 LEU A CD2   1 
ATOM   1810 N N     . LYS A 1 219 ? 28.08940  -1.15225  13.90098  1.000 14.40639  ? 1225 LYS A N     1 
ATOM   1811 C CA    . LYS A 1 219 ? 29.12606  -0.25199  14.38472  1.000 16.00360  ? 1225 LYS A CA    1 
ATOM   1812 C C     . LYS A 1 219 ? 30.44562  -0.96746  14.60682  1.000 16.30015  ? 1225 LYS A C     1 
ATOM   1813 O O     . LYS A 1 219 ? 31.50990  -0.34886  14.49746  1.000 17.98483  ? 1225 LYS A O     1 
ATOM   1814 C CB    . LYS A 1 219 ? 28.67700  0.43494   15.67350  1.000 19.38933  ? 1225 LYS A CB    1 
ATOM   1815 C CG    . LYS A 1 219 ? 27.29140  1.05275   15.59630  1.000 24.26188  ? 1225 LYS A CG    1 
ATOM   1816 C CD    . LYS A 1 219 ? 27.17802  2.24679   16.52234  1.000 28.54727  ? 1225 LYS A CD    1 
ATOM   1817 C CE    . LYS A 1 219 ? 25.96372  3.09016   16.18336  1.000 31.87026  ? 1225 LYS A CE    1 
ATOM   1818 N NZ    . LYS A 1 219 ? 24.76543  2.64562   16.95509  1.000 33.50689  ? 1225 LYS A NZ    1 
ATOM   1819 N N     . GLN A 1 220 ? 30.39735  -2.25985  14.90207  1.000 15.01072  ? 1226 GLN A N     1 
ATOM   1820 C CA    . GLN A 1 220 ? 31.59592  -3.03967  15.16897  1.000 16.44262  ? 1226 GLN A CA    1 
ATOM   1821 C C     . GLN A 1 220 ? 32.20595  -3.60758  13.89903  1.000 14.73342  ? 1226 GLN A C     1 
ATOM   1822 O O     . GLN A 1 220 ? 33.43356  -3.70843  13.79345  1.000 15.82710  ? 1226 GLN A O     1 
ATOM   1823 C CB    . GLN A 1 220 ? 31.24907  -4.19813  16.10324  1.000 19.68625  ? 1226 GLN A CB    1 
ATOM   1824 C CG    . GLN A 1 220 ? 30.89523  -3.77430  17.50961  1.000 24.98453  ? 1226 GLN A CG    1 
ATOM   1825 C CD    . GLN A 1 220 ? 30.27779  -4.90197  18.31314  1.000 30.44274  ? 1226 GLN A CD    1 
ATOM   1826 O OE1   . GLN A 1 220 ? 30.30831  -6.06002  17.89382  1.000 32.95411  ? 1226 GLN A OE1   1 
ATOM   1827 N NE2   . GLN A 1 220 ? 29.72019  -4.57220  19.47477  1.000 32.20709  ? 1226 GLN A NE2   1 
ATOM   1828 N N     . TYR A 1 221 ? 31.36897  -3.99344  12.93897  1.000 13.41830  ? 1227 TYR A N     1 
ATOM   1829 C CA    . TYR A 1 221 ? 31.82071  -4.64456  11.70786  1.000 13.05367  ? 1227 TYR A CA    1 
ATOM   1830 C C     . TYR A 1 221 ? 31.16252  -3.98402  10.50203  1.000 12.27253  ? 1227 TYR A C     1 
ATOM   1831 O O     . TYR A 1 221 ? 30.48103  -4.64110  9.70643   1.000 11.98092  ? 1227 TYR A O     1 
ATOM   1832 C CB    . TYR A 1 221 ? 31.52039  -6.14122  11.74982  1.000 13.84378  ? 1227 TYR A CB    1 
ATOM   1833 C CG    . TYR A 1 221 ? 32.32696  -6.84603  12.81056  1.000 15.08200  ? 1227 TYR A CG    1 
ATOM   1834 C CD1   . TYR A 1 221 ? 33.62664  -7.28439  12.56251  1.000 17.08206  ? 1227 TYR A CD1   1 
ATOM   1835 C CD2   . TYR A 1 221 ? 31.80157  -7.04792  14.08180  1.000 16.14366  ? 1227 TYR A CD2   1 
ATOM   1836 C CE1   . TYR A 1 221 ? 34.37243  -7.92159  13.55234  1.000 18.97035  ? 1227 TYR A CE1   1 
ATOM   1837 C CE2   . TYR A 1 221 ? 32.54081  -7.67135  15.07081  1.000 17.59552  ? 1227 TYR A CE2   1 
ATOM   1838 C CZ    . TYR A 1 221 ? 33.82258  -8.10536  14.79900  1.000 19.54702  ? 1227 TYR A CZ    1 
ATOM   1839 O OH    . TYR A 1 221 ? 34.55762  -8.72860  15.78460  1.000 21.51353  ? 1227 TYR A OH    1 
ATOM   1840 N N     . PRO A 1 222 ? 31.37555  -2.67603  10.32107  1.000 12.65093  ? 1228 PRO A N     1 
ATOM   1841 C CA    . PRO A 1 222 ? 30.67180  -1.95871  9.24210   1.000 12.84929  ? 1228 PRO A CA    1 
ATOM   1842 C C     . PRO A 1 222 ? 31.01026  -2.45230  7.85330   1.000 13.06320  ? 1228 PRO A C     1 
ATOM   1843 O O     . PRO A 1 222 ? 30.23162  -2.21328  6.92231   1.000 14.08019  ? 1228 PRO A O     1 
ATOM   1844 C CB    . PRO A 1 222 ? 31.12773  -0.50663  9.43467   1.000 13.76674  ? 1228 PRO A CB    1 
ATOM   1845 C CG    . PRO A 1 222 ? 32.48036  -0.64357  10.08875  1.000 14.09905  ? 1228 PRO A CG    1 
ATOM   1846 C CD    . PRO A 1 222 ? 32.32256  -1.79937  11.03473  1.000 13.62198  ? 1228 PRO A CD    1 
ATOM   1847 N N     . ASP A 1 223 ? 32.15710  -3.09434  7.66549   1.000 12.08854  ? 1229 ASP A N     1 
ATOM   1848 C CA    A ASP A 1 223 ? 32.53172  -3.60402  6.35338   0.502 12.93351  ? 1229 ASP A CA    1 
ATOM   1849 C CA    B ASP A 1 223 ? 32.55767  -3.61027  6.36540   0.498 13.40029  ? 1229 ASP A CA    1 
ATOM   1850 C C     . ASP A 1 223 ? 32.20107  -5.07841  6.17141   1.000 12.79881  ? 1229 ASP A C     1 
ATOM   1851 O O     . ASP A 1 223 ? 32.49539  -5.63760  5.11145   1.000 14.91932  ? 1229 ASP A O     1 
ATOM   1852 C CB    A ASP A 1 223 ? 34.01518  -3.34454  6.06464   0.502 14.77539  ? 1229 ASP A CB    1 
ATOM   1853 C CB    B ASP A 1 223 ? 34.05996  -3.40093  6.16552   0.498 16.44758  ? 1229 ASP A CB    1 
ATOM   1854 C CG    A ASP A 1 223 ? 34.28122  -3.07274  4.59580   0.502 18.33829  ? 1229 ASP A CG    1 
ATOM   1855 C CG    B ASP A 1 223 ? 34.41394  -3.05024  4.74253   0.498 19.95521  ? 1229 ASP A CG    1 
ATOM   1856 O OD1   A ASP A 1 223 ? 33.42532  -2.44104  3.93660   0.502 19.17012  ? 1229 ASP A OD1   1 
ATOM   1857 O OD1   B ASP A 1 223 ? 33.63803  -2.31993  4.08427   0.498 20.90272  ? 1229 ASP A OD1   1 
ATOM   1858 O OD2   A ASP A 1 223 ? 35.34866  -3.48411  4.09499   0.502 20.99758  ? 1229 ASP A OD2   1 
ATOM   1859 O OD2   B ASP A 1 223 ? 35.48539  -3.49892  4.28928   0.498 22.04644  ? 1229 ASP A OD2   1 
ATOM   1860 N N     . ASN A 1 224 ? 31.57881  -5.71448  7.16604   1.000 11.66979  ? 1230 ASN A N     1 
ATOM   1861 C CA    . ASN A 1 224 ? 31.23905  -7.12561  7.07532   1.000 11.34545  ? 1230 ASN A CA    1 
ATOM   1862 C C     . ASN A 1 224 ? 29.78809  -7.44101  7.39883   1.000 10.75204  ? 1230 ASN A C     1 
ATOM   1863 O O     . ASN A 1 224 ? 29.38564  -8.60204  7.24814   1.000 10.77136  ? 1230 ASN A O     1 
ATOM   1864 C CB    . ASN A 1 224 ? 32.14066  -7.97229  7.99164   1.000 12.30317  ? 1230 ASN A CB    1 
ATOM   1865 C CG    . ASN A 1 224 ? 33.60936  -7.79372  7.68875   1.000 12.86957  ? 1230 ASN A CG    1 
ATOM   1866 O OD1   . ASN A 1 224 ? 34.26713  -6.93357  8.26320   1.000 14.41907  ? 1230 ASN A OD1   1 
ATOM   1867 N ND2   . ASN A 1 224 ? 34.13251  -8.59565  6.77518   1.000 12.67276  ? 1230 ASN A ND2   1 
ATOM   1868 N N     . PHE A 1 225 ? 28.99397  -6.46358  7.82563   1.000 11.22023  ? 1231 PHE A N     1 
ATOM   1869 C CA    . PHE A 1 225 ? 27.62469  -6.71145  8.23925   1.000 11.29866  ? 1231 PHE A CA    1 
ATOM   1870 C C     . PHE A 1 225 ? 26.72975  -5.61088  7.70060   1.000 11.47655  ? 1231 PHE A C     1 
ATOM   1871 O O     . PHE A 1 225 ? 27.07230  -4.42749  7.79396   1.000 13.35263  ? 1231 PHE A O     1 
ATOM   1872 C CB    . PHE A 1 225 ? 27.48866  -6.74493  9.76572   1.000 11.37995  ? 1231 PHE A CB    1 
ATOM   1873 C CG    . PHE A 1 225 ? 26.09269  -7.00886  10.23661  1.000 10.68827  ? 1231 PHE A CG    1 
ATOM   1874 C CD1   . PHE A 1 225 ? 25.48361  -8.22201  9.96723   1.000 10.95150  ? 1231 PHE A CD1   1 
ATOM   1875 C CD2   . PHE A 1 225 ? 25.38277  -6.05236  10.94026  1.000 11.66069  ? 1231 PHE A CD2   1 
ATOM   1876 C CE1   . PHE A 1 225 ? 24.19031  -8.48225  10.38298  1.000 11.55444  ? 1231 PHE A CE1   1 
ATOM   1877 C CE2   . PHE A 1 225 ? 24.08488  -6.30501  11.37878  1.000 12.65171  ? 1231 PHE A CE2   1 
ATOM   1878 C CZ    . PHE A 1 225 ? 23.49052  -7.53192  11.09847  1.000 11.80778  ? 1231 PHE A CZ    1 
ATOM   1879 N N     . ARG A 1 226 ? 25.58397  -6.01180  7.14984   1.000 10.81898  ? 1232 ARG A N     1 
ATOM   1880 C CA    . ARG A 1 226 ? 24.52081  -5.10414  6.74469   1.000 11.39590  ? 1232 ARG A CA    1 
ATOM   1881 C C     . ARG A 1 226 ? 23.21186  -5.59301  7.34921   1.000 11.15794  ? 1232 ARG A C     1 
ATOM   1882 O O     . ARG A 1 226 ? 23.04815  -6.78307  7.62424   1.000 10.83766  ? 1232 ARG A O     1 
ATOM   1883 C CB    . ARG A 1 226 ? 24.42382  -5.01429  5.21814   1.000 12.39691  ? 1232 ARG A CB    1 
ATOM   1884 C CG    . ARG A 1 226 ? 25.67132  -4.40664  4.59925   1.000 13.55893  ? 1232 ARG A CG    1 
ATOM   1885 C CD    . ARG A 1 226 ? 25.65639  -4.46918  3.08232   1.000 15.01023  ? 1232 ARG A CD    1 
ATOM   1886 N NE    . ARG A 1 226 ? 24.69456  -3.54744  2.49831   1.000 15.08062  ? 1232 ARG A NE    1 
ATOM   1887 C CZ    . ARG A 1 226 ? 24.71375  -3.18073  1.22268   1.000 16.31732  ? 1232 ARG A CZ    1 
ATOM   1888 N NH1   . ARG A 1 226 ? 25.65070  -3.61375  0.39579   1.000 17.48565  ? 1232 ARG A NH1   1 
ATOM   1889 N NH2   . ARG A 1 226 ? 23.76544  -2.36902  0.75986   1.000 17.03672  ? 1232 ARG A NH2   1 
ATOM   1890 N N     . TYR A 1 227 ? 22.26515  -4.66840  7.52571   1.000 11.81269  ? 1233 TYR A N     1 
ATOM   1891 C CA    . TYR A 1 227 ? 21.06575  -4.94488  8.31380   1.000 12.23166  ? 1233 TYR A CA    1 
ATOM   1892 C C     . TYR A 1 227 ? 19.94210  -4.05085  7.81651   1.000 12.86171  ? 1233 TYR A C     1 
ATOM   1893 O O     . TYR A 1 227 ? 20.06536  -2.82272  7.85683   1.000 14.35075  ? 1233 TYR A O     1 
ATOM   1894 C CB    . TYR A 1 227 ? 21.36397  -4.65123  9.78099   1.000 12.31206  ? 1233 TYR A CB    1 
ATOM   1895 C CG    . TYR A 1 227 ? 20.25393  -4.85941  10.78149  1.000 12.22839  ? 1233 TYR A CG    1 
ATOM   1896 C CD1   . TYR A 1 227 ? 19.32556  -5.88729  10.65893  1.000 12.47829  ? 1233 TYR A CD1   1 
ATOM   1897 C CD2   . TYR A 1 227 ? 20.17979  -4.04550  11.90232  1.000 12.78417  ? 1233 TYR A CD2   1 
ATOM   1898 C CE1   . TYR A 1 227 ? 18.32813  -6.07402  11.62649  1.000 13.09580  ? 1233 TYR A CE1   1 
ATOM   1899 C CE2   . TYR A 1 227 ? 19.20342  -4.22545  12.87229  1.000 13.37921  ? 1233 TYR A CE2   1 
ATOM   1900 C CZ    . TYR A 1 227 ? 18.28411  -5.24266  12.73509  1.000 12.63538  ? 1233 TYR A CZ    1 
ATOM   1901 O OH    . TYR A 1 227 ? 17.31981  -5.42233  13.69788  1.000 13.41404  ? 1233 TYR A OH    1 
ATOM   1902 N N     . ASP A 1 228 ? 18.85270  -4.66083  7.35146   1.000 13.37803  ? 1234 ASP A N     1 
ATOM   1903 C CA    . ASP A 1 228 ? 17.71591  -3.92478  6.82111   1.000 13.99092  ? 1234 ASP A CA    1 
ATOM   1904 C C     . ASP A 1 228 ? 16.42508  -4.50365  7.37134   1.000 14.78264  ? 1234 ASP A C     1 
ATOM   1905 O O     . ASP A 1 228 ? 16.26958  -5.72352  7.45172   1.000 14.26185  ? 1234 ASP A O     1 
ATOM   1906 C CB    . ASP A 1 228 ? 17.71967  -3.97288  5.29863   1.000 15.13848  ? 1234 ASP A CB    1 
ATOM   1907 C CG    . ASP A 1 228 ? 18.80509  -3.10475  4.71066   1.000 14.40141  ? 1234 ASP A CG    1 
ATOM   1908 O OD1   . ASP A 1 228 ? 18.59208  -1.87587  4.61711   1.000 15.17267  ? 1234 ASP A OD1   1 
ATOM   1909 O OD2   . ASP A 1 228 ? 19.87454  -3.63890  4.35307   1.000 14.10187  ? 1234 ASP A OD2   1 
ATOM   1910 N N     . LYS A 1 229 ? 15.50043  -3.62043  7.73775   1.000 15.77959  ? 1235 LYS A N     1 
ATOM   1911 C CA    . LYS A 1 229 ? 14.27659  -3.99913  8.42349   1.000 17.19357  ? 1235 LYS A CA    1 
ATOM   1912 C C     . LYS A 1 229 ? 13.05179  -3.54134  7.64735   1.000 19.05233  ? 1235 LYS A C     1 
ATOM   1913 O O     . LYS A 1 229 ? 13.05419  -2.48437  7.00804   1.000 19.25095  ? 1235 LYS A O     1 
ATOM   1914 C CB    . LYS A 1 229 ? 14.21329  -3.35205  9.80559   1.000 17.27622  ? 1235 LYS A CB    1 
ATOM   1915 C CG    . LYS A 1 229 ? 15.11764  -4.02313  10.81370  1.000 16.62431  ? 1235 LYS A CG    1 
ATOM   1916 C CD    . LYS A 1 229 ? 15.34611  -3.14546  12.03950  1.000 16.93532  ? 1235 LYS A CD    1 
ATOM   1917 C CE    . LYS A 1 229 ? 16.45952  -2.14300  11.81413  1.000 17.21348  ? 1235 LYS A CE    1 
ATOM   1918 N NZ    . LYS A 1 229 ? 16.72249  -1.31156  13.02727  1.000 18.71484  ? 1235 LYS A NZ    1 
ATOM   1919 N N     A ALA A 1 230 ? 11.99823  -4.35418  7.71761   0.559 17.53746  ? 1236 ALA A N     1 
ATOM   1920 N N     B ALA A 1 230 ? 11.99514  -4.33371  7.72882   0.441 22.84576  ? 1236 ALA A N     1 
ATOM   1921 C CA    A ALA A 1 230 ? 10.69625  -4.03397  7.14526   0.559 17.04146  ? 1236 ALA A CA    1 
ATOM   1922 C CA    B ALA A 1 230 ? 10.70234  -3.96693  7.16488   0.441 27.06182  ? 1236 ALA A CA    1 
ATOM   1923 C C     A ALA A 1 230 ? 9.63469   -4.18823  8.22558   0.559 16.03289  ? 1236 ALA A C     1 
ATOM   1924 C C     B ALA A 1 230 ? 9.72637   -3.85101  8.32772   0.441 25.03636  ? 1236 ALA A C     1 
ATOM   1925 O O     A ALA A 1 230 ? 9.55516   -5.23410  8.87687   0.559 15.26619  ? 1236 ALA A O     1 
ATOM   1926 O O     B ALA A 1 230 ? 9.28537   -4.86425  8.87892   0.441 24.40185  ? 1236 ALA A O     1 
ATOM   1927 C CB    A ALA A 1 230 ? 10.38244  -4.96338  5.97008   0.559 16.99402  ? 1236 ALA A CB    1 
ATOM   1928 C CB    B ALA A 1 230 ? 10.24244  -5.00727  6.15655   0.441 33.13646  ? 1236 ALA A CB    1 
ATOM   1929 N N     A LEU A 1 231 ? 8.81081   -3.15648  8.40137   0.559 16.06302  ? 1237 LEU A N     1 
ATOM   1930 N N     B LEU A 1 231 ? 9.41226   -2.61851  8.71653   0.441 22.91699  ? 1237 LEU A N     1 
ATOM   1931 C CA    A LEU A 1 231 ? 7.83408   -3.08449  9.48824   0.559 16.53273  ? 1237 LEU A CA    1 
ATOM   1932 C CA    B LEU A 1 231 ? 8.39342   -2.35257  9.72817   0.441 22.37107  ? 1237 LEU A CA    1 
ATOM   1933 C C     A LEU A 1 231 ? 6.46356   -3.02236  8.80842   0.559 16.83549  ? 1237 LEU A C     1 
ATOM   1934 C C     B LEU A 1 231 ? 7.11301   -2.07387  8.94983   0.441 22.09674  ? 1237 LEU A C     1 
ATOM   1935 O O     A LEU A 1 231 ? 6.05425   -1.95989  8.32619   0.559 17.58069  ? 1237 LEU A O     1 
ATOM   1936 O O     B LEU A 1 231 ? 6.83456   -0.93876  8.56089   0.441 20.91917  ? 1237 LEU A O     1 
ATOM   1937 C CB    A LEU A 1 231 ? 8.08086   -1.82230  10.30781  0.559 17.13015  ? 1237 LEU A CB    1 
ATOM   1938 C CB    B LEU A 1 231 ? 8.79664   -1.17051  10.59938  0.441 22.75879  ? 1237 LEU A CB    1 
ATOM   1939 C CG    A LEU A 1 231 ? 9.47480   -1.70623  10.93658  0.559 16.97344  ? 1237 LEU A CG    1 
ATOM   1940 C CG    B LEU A 1 231 ? 10.17743  -1.25841  11.24989  0.441 23.55061  ? 1237 LEU A CG    1 
ATOM   1941 C CD1   A LEU A 1 231 ? 9.64080   -0.38162  11.68376  0.559 16.85874  ? 1237 LEU A CD1   1 
ATOM   1942 C CD1   B LEU A 1 231 ? 10.41294  -0.06225  12.16293  0.441 23.95290  ? 1237 LEU A CD1   1 
ATOM   1943 C CD2   A LEU A 1 231 ? 9.84558   -2.89070  11.79993  0.559 17.27646  ? 1237 LEU A CD2   1 
ATOM   1944 C CD2   B LEU A 1 231 ? 10.34382  -2.57089  11.99815  0.441 23.80010  ? 1237 LEU A CD2   1 
ATOM   1945 N N     A SER A 1 232 ? 5.73867   -4.14702  8.78493   0.559 17.46226  ? 1238 SER A N     1 
ATOM   1946 N N     B SER A 1 232 ? 6.33095   -3.13200  8.71695   0.441 23.50996  ? 1238 SER A N     1 
ATOM   1947 C CA    A SER A 1 232 ? 4.61793   -4.30478  7.85208   0.559 17.96115  ? 1238 SER A CA    1 
ATOM   1948 C CA    B SER A 1 232 ? 5.22900   -3.04831  7.76021   0.441 25.16425  ? 1238 SER A CA    1 
ATOM   1949 C C     A SER A 1 232 ? 3.45303   -3.36536  8.16020   0.559 17.75754  ? 1238 SER A C     1 
ATOM   1950 C C     B SER A 1 232 ? 4.17939   -2.02702  8.18337   0.441 24.28175  ? 1238 SER A C     1 
ATOM   1951 O O     A SER A 1 232 ? 2.82156   -2.83053  7.23799   0.559 19.08569  ? 1238 SER A O     1 
ATOM   1952 O O     B SER A 1 232 ? 3.63153   -1.30808  7.34000   0.441 24.28658  ? 1238 SER A O     1 
ATOM   1953 C CB    A SER A 1 232 ? 4.15195   -5.76048  7.83295   0.559 19.20746  ? 1238 SER A CB    1 
ATOM   1954 C CB    B SER A 1 232 ? 4.59648   -4.42576  7.55832   0.441 27.27033  ? 1238 SER A CB    1 
ATOM   1955 O OG    A SER A 1 232 ? 3.42129   -6.08271  9.00073   0.559 20.62749  ? 1238 SER A OG    1 
ATOM   1956 O OG    B SER A 1 232 ? 5.58145   -5.40241  7.26322   0.441 29.56164  ? 1238 SER A OG    1 
ATOM   1957 N N     A ARG A 1 233 ? 3.13310   -3.17591  9.44090   0.559 17.18925  ? 1239 ARG A N     1 
ATOM   1958 N N     B ARG A 1 233 ? 3.88549   -1.94629  9.48198   0.441 24.20835  ? 1239 ARG A N     1 
ATOM   1959 C CA    A ARG A 1 233 ? 2.00709   -2.34173  9.83706   0.559 17.39664  ? 1239 ARG A CA    1 
ATOM   1960 C CA    B ARG A 1 233 ? 2.83710   -1.05565  9.96463   0.441 25.04643  ? 1239 ARG A CA    1 
ATOM   1961 C C     A ARG A 1 233 ? 2.36453   -0.86497  9.93929   0.559 18.10376  ? 1239 ARG A C     1 
ATOM   1962 C C     B ARG A 1 233 ? 3.26033   0.40589   10.00456  0.441 23.95523  ? 1239 ARG A C     1 
ATOM   1963 O O     A ARG A 1 233 ? 1.46537   -0.03859  10.12524  0.559 19.06768  ? 1239 ARG A O     1 
ATOM   1964 O O     B ARG A 1 233 ? 2.39575   1.27653   10.13484  0.441 23.66293  ? 1239 ARG A O     1 
ATOM   1965 C CB    A ARG A 1 233 ? 1.42272   -2.83790  11.15771  0.559 17.53673  ? 1239 ARG A CB    1 
ATOM   1966 C CB    B ARG A 1 233 ? 2.38121   -1.47164  11.36599  0.441 26.57712  ? 1239 ARG A CB    1 
ATOM   1967 C CG    A ARG A 1 233 ? 0.90470   -4.26346  11.10302  0.559 19.11464  ? 1239 ARG A CG    1 
ATOM   1968 C CG    B ARG A 1 233 ? 1.43960   -2.66491  11.41368  0.441 28.49429  ? 1239 ARG A CG    1 
ATOM   1969 C CD    A ARG A 1 233 ? 0.32218   -4.66249  12.43774  0.559 20.84173  ? 1239 ARG A CD    1 
ATOM   1970 C CD    B ARG A 1 233 ? 1.39934   -3.25426  12.81866  0.441 30.46976  ? 1239 ARG A CD    1 
ATOM   1971 N NE    A ARG A 1 233 ? -0.26029  -5.99813  12.42030  0.559 23.55787  ? 1239 ARG A NE    1 
ATOM   1972 N NE    B ARG A 1 233 ? 1.10814   -4.68274  12.81035  0.441 31.99499  ? 1239 ARG A NE    1 
ATOM   1973 C CZ    A ARG A 1 233 ? -1.06394  -6.46839  13.36405  0.559 25.01553  ? 1239 ARG A CZ    1 
ATOM   1974 C CZ    B ARG A 1 233 ? -0.10673  -5.20219  12.69896  0.441 32.90389  ? 1239 ARG A CZ    1 
ATOM   1975 N NH1   A ARG A 1 233 ? -1.42461  -5.72488  14.39676  0.559 25.23160  ? 1239 ARG A NH1   1 
ATOM   1976 N NH1   B ARG A 1 233 ? -1.18524  -4.43717  12.66388  0.441 33.63899  ? 1239 ARG A NH1   1 
ATOM   1977 N NH2   A ARG A 1 233 ? -1.51572  -7.71540  13.27030  0.559 25.83179  ? 1239 ARG A NH2   1 
ATOM   1978 N NH2   B ARG A 1 233 ? -0.24345  -6.52366  12.63327  0.441 32.99029  ? 1239 ARG A NH2   1 
ATOM   1979 N N     A GLU A 1 234 ? 3.64258   -0.51530  9.81239   0.559 17.95713  ? 1240 GLU A N     1 
ATOM   1980 N N     B GLU A 1 234 ? 4.55751   0.70418   9.91182   0.441 22.79532  ? 1240 GLU A N     1 
ATOM   1981 C CA    A GLU A 1 234 ? 4.09261   0.86164   9.91690   0.559 17.82989  ? 1240 GLU A CA    1 
ATOM   1982 C CA    B GLU A 1 234 ? 5.01846   2.07809   10.07201  0.441 22.50872  ? 1240 GLU A CA    1 
ATOM   1983 C C     A GLU A 1 234 ? 4.73670   1.38172   8.64239   0.559 16.22956  ? 1240 GLU A C     1 
ATOM   1984 C C     B GLU A 1 234 ? 6.01885   2.52529   9.01391   0.441 20.08689  ? 1240 GLU A C     1 
ATOM   1985 O O     A GLU A 1 234 ? 5.05668   2.57232   8.57630   0.559 17.28426  ? 1240 GLU A O     1 
ATOM   1986 O O     B GLU A 1 234 ? 6.61250   3.60120   9.15978   0.441 21.42161  ? 1240 GLU A O     1 
ATOM   1987 C CB    A GLU A 1 234 ? 5.07257   1.02588   11.09452  0.559 19.70071  ? 1240 GLU A CB    1 
ATOM   1988 C CB    B GLU A 1 234 ? 5.58270   2.32122   11.47528  0.441 24.61417  ? 1240 GLU A CB    1 
ATOM   1989 C CG    A GLU A 1 234 ? 4.40362   0.90231   12.46385  0.559 20.99836  ? 1240 GLU A CG    1 
ATOM   1990 C CG    B GLU A 1 234 ? 6.42239   1.19138   12.01466  0.441 25.94992  ? 1240 GLU A CG    1 
ATOM   1991 C CD    A GLU A 1 234 ? 5.38142   0.83358   13.63568  0.559 22.31770  ? 1240 GLU A CD    1 
ATOM   1992 C CD    B GLU A 1 234 ? 7.10950   1.56702   13.30380  0.441 26.92296  ? 1240 GLU A CD    1 
ATOM   1993 O OE1   A GLU A 1 234 ? 6.57483   0.53470   13.42601  0.559 22.77788  ? 1240 GLU A OE1   1 
ATOM   1994 O OE1   B GLU A 1 234 ? 7.93801   2.50321   13.28914  0.441 27.04020  ? 1240 GLU A OE1   1 
ATOM   1995 O OE2   A GLU A 1 234 ? 4.94451   1.04793   14.78878  0.559 22.92280  ? 1240 GLU A OE2   1 
ATOM   1996 O OE2   B GLU A 1 234 ? 6.80186   0.93835   14.33469  0.441 27.49641  ? 1240 GLU A OE2   1 
ATOM   1997 N N     A GLN A 1 235 ? 4.93839   0.53217   7.63684   0.559 15.23355  ? 1241 GLN A N     1 
ATOM   1998 N N     B GLN A 1 235 ? 6.22109   1.74510   7.95732   0.441 17.35234  ? 1241 GLN A N     1 
ATOM   1999 C CA    A GLN A 1 235 ? 5.60451   0.93073   6.40757   0.559 15.12652  ? 1241 GLN A CA    1 
ATOM   2000 C CA    B GLN A 1 235 ? 7.07530   2.15781   6.85746   0.441 15.79363  ? 1241 GLN A CA    1 
ATOM   2001 C C     A GLN A 1 235 ? 4.87565   0.32629   5.21900   0.559 15.79080  ? 1241 GLN A C     1 
ATOM   2002 C C     B GLN A 1 235 ? 6.39538   1.84652   5.53738   0.441 15.63600  ? 1241 GLN A C     1 
ATOM   2003 O O     A GLN A 1 235 ? 4.18821   -0.69292  5.33380   0.559 15.56379  ? 1241 GLN A O     1 
ATOM   2004 O O     B GLN A 1 235 ? 5.65077   0.86990   5.41455   0.441 16.19825  ? 1241 GLN A O     1 
ATOM   2005 C CB    A GLN A 1 235 ? 7.06552   0.47199   6.36622   0.559 14.23312  ? 1241 GLN A CB    1 
ATOM   2006 C CB    B GLN A 1 235 ? 8.42249   1.44291   6.87772   0.441 15.25954  ? 1241 GLN A CB    1 
ATOM   2007 C CG    A GLN A 1 235 ? 7.90789   0.95672   7.51720   0.559 14.07281  ? 1241 GLN A CG    1 
ATOM   2008 C CG    B GLN A 1 235 ? 9.31155   1.83421   8.03086   0.441 15.52125  ? 1241 GLN A CG    1 
ATOM   2009 C CD    A GLN A 1 235 ? 9.24485   0.24383   7.58309   0.559 13.71799  ? 1241 GLN A CD    1 
ATOM   2010 C CD    B GLN A 1 235 ? 10.55763  0.98403   8.10038   0.441 15.47259  ? 1241 GLN A CD    1 
ATOM   2011 O OE1   A GLN A 1 235 ? 9.39569   -0.87645  7.08758   0.559 13.31017  ? 1241 GLN A OE1   1 
ATOM   2012 O OE1   B GLN A 1 235 ? 10.61665  -0.10095  7.52410   0.441 14.59625  ? 1241 GLN A OE1   1 
ATOM   2013 N NE2   A GLN A 1 235 ? 10.22371  0.89067   8.19906   0.559 14.83358  ? 1241 GLN A NE2   1 
ATOM   2014 N NE2   B GLN A 1 235 ? 11.56710  1.47611   8.80199   0.441 15.09582  ? 1241 GLN A NE2   1 
ATOM   2015 N N     A LYS A 1 236 ? 5.04409   0.96965   4.06364   0.559 17.98387  ? 1242 LYS A N     1 
ATOM   2016 N N     B LYS A 1 236 ? 6.66997   2.68651   4.54854   0.441 14.49850  ? 1242 LYS A N     1 
ATOM   2017 C CA    A LYS A 1 236 ? 4.39325   0.55491   2.83164   0.559 20.21894  ? 1242 LYS A CA    1 
ATOM   2018 C CA    B LYS A 1 236 ? 6.18814   2.48314   3.19454   0.441 14.81184  ? 1242 LYS A CA    1 
ATOM   2019 C C     A LYS A 1 236 ? 5.42437   0.43304   1.72325   0.559 19.38530  ? 1242 LYS A C     1 
ATOM   2020 C C     B LYS A 1 236 ? 7.37647   2.27933   2.27059   0.441 14.74271  ? 1242 LYS A C     1 
ATOM   2021 O O     A LYS A 1 236 ? 6.36934   1.22505   1.65289   0.559 20.88923  ? 1242 LYS A O     1 
ATOM   2022 O O     B LYS A 1 236 ? 8.44053   2.87595   2.46694   0.441 16.23748  ? 1242 LYS A O     1 
ATOM   2023 C CB    A LYS A 1 236 ? 3.31963   1.56504   2.45222   0.559 23.43125  ? 1242 LYS A CB    1 
ATOM   2024 C CB    B LYS A 1 236 ? 5.35761   3.67490   2.72205   0.441 16.15584  ? 1242 LYS A CB    1 
ATOM   2025 C CG    A LYS A 1 236 ? 2.48981   1.87600   3.65991   0.559 63.43202  ? 1242 LYS A CG    1 
ATOM   2026 C CG    B LYS A 1 236 ? 4.03167   3.81030   3.44525   0.441 40.18121  ? 1242 LYS A CG    1 
ATOM   2027 C CD    A LYS A 1 236 ? 1.75483   0.61836   4.05213   0.559 81.26895  ? 1242 LYS A CD    1 
ATOM   2028 C CD    B LYS A 1 236 ? 3.39858   2.45222   3.73547   0.441 66.64097  ? 1242 LYS A CD    1 
ATOM   2029 C CE    A LYS A 1 236 ? 0.76370   0.88123   5.13055   0.559 72.15014  ? 1242 LYS A CE    1 
ATOM   2030 C CE    B LYS A 1 236 ? 1.93069   2.43047   3.34147   0.441 76.80233  ? 1242 LYS A CE    1 
ATOM   2031 N NZ    A LYS A 1 236 ? 0.16326   -0.40020  5.58711   0.559 78.25510  ? 1242 LYS A NZ    1 
ATOM   2032 N NZ    B LYS A 1 236 ? 1.33036   1.07552   3.33627   0.441 67.93270  ? 1242 LYS A NZ    1 
ATOM   2033 N N     A ASN A 1 237 ? 5.24587   -0.57044  0.86704   0.559 17.73154  ? 1243 ASN A N     1 
ATOM   2034 N N     B ASN A 1 237 ? 7.20008   1.40790   1.28446   0.441 16.25698  ? 1243 ASN A N     1 
ATOM   2035 C CA    A ASN A 1 237 ? 6.16247   -0.74429  -0.24574  0.559 16.92920  ? 1243 ASN A CA    1 
ATOM   2036 C CA    B ASN A 1 237 ? 8.20837   1.23573   0.25610   0.441 17.22295  ? 1243 ASN A CA    1 
ATOM   2037 C C     A ASN A 1 237 ? 5.83784   0.25308   -1.35748  0.559 18.21693  ? 1243 ASN A C     1 
ATOM   2038 C C     B ASN A 1 237 ? 8.19175   2.44451   -0.68030  0.441 18.08612  ? 1243 ASN A C     1 
ATOM   2039 O O     A ASN A 1 237 ? 4.84589   0.98585   -1.30868  0.559 18.71969  ? 1243 ASN A O     1 
ATOM   2040 O O     B ASN A 1 237 ? 7.36233   3.34978   -0.55996  0.441 18.11200  ? 1243 ASN A O     1 
ATOM   2041 C CB    A ASN A 1 237 ? 6.14584   -2.18912  -0.76024  0.559 16.85321  ? 1243 ASN A CB    1 
ATOM   2042 C CB    B ASN A 1 237 ? 7.99329   -0.09103  -0.47082  0.441 18.63684  ? 1243 ASN A CB    1 
ATOM   2043 C CG    A ASN A 1 237 ? 4.75742   -2.67101  -1.12921  0.559 17.70065  ? 1243 ASN A CG    1 
ATOM   2044 C CG    B ASN A 1 237 ? 9.18067   -0.48983  -1.32406  0.441 21.71017  ? 1243 ASN A CG    1 
ATOM   2045 O OD1   A ASN A 1 237 ? 4.07692   -2.03484  -1.91550  0.559 19.03345  ? 1243 ASN A OD1   1 
ATOM   2046 O OD1   B ASN A 1 237 ? 10.30674  -0.04273  -1.09163  0.441 24.77295  ? 1243 ASN A OD1   1 
ATOM   2047 N ND2   A ASN A 1 237 ? 4.34839   -3.81499  -0.59755  0.559 17.45820  ? 1243 ASN A ND2   1 
ATOM   2048 N ND2   B ASN A 1 237 ? 8.93996   -1.34667  -2.30712  0.441 20.94365  ? 1243 ASN A ND2   1 
ATOM   2049 N N     A ARG A 1 238 ? 6.70181   0.27180   -2.37093  0.559 19.57784  ? 1244 ARG A N     1 
ATOM   2050 N N     B ARG A 1 238 ? 9.13376   2.46621   -1.62484  0.441 19.73796  ? 1244 ARG A N     1 
ATOM   2051 C CA    A ARG A 1 238 ? 6.51071   1.18214   -3.49453  0.559 21.74817  ? 1244 ARG A CA    1 
ATOM   2052 C CA    B ARG A 1 238 ? 9.26304   3.61282   -2.51754  0.441 22.54635  ? 1244 ARG A CA    1 
ATOM   2053 C C     A ARG A 1 238 ? 5.21345   0.89607   -4.24186  0.559 23.53760  ? 1244 ARG A C     1 
ATOM   2054 C C     B ARG A 1 238 ? 8.05315   3.78977   -3.42526  0.441 23.60559  ? 1244 ARG A C     1 
ATOM   2055 O O     A ARG A 1 238 ? 4.66965   1.78868   -4.90343  0.559 25.23792  ? 1244 ARG A O     1 
ATOM   2056 O O     B ARG A 1 238 ? 7.85962   4.88007   -3.97131  0.441 24.27170  ? 1244 ARG A O     1 
ATOM   2057 C CB    A ARG A 1 238 ? 7.71146   1.09804   -4.43463  0.559 23.72003  ? 1244 ARG A CB    1 
ATOM   2058 C CB    B ARG A 1 238 ? 10.55218  3.51411   -3.33577  0.441 24.96794  ? 1244 ARG A CB    1 
ATOM   2059 C CG    A ARG A 1 238 ? 7.97659   -0.29602  -4.96272  0.559 19.52667  ? 1244 ARG A CG    1 
ATOM   2060 C CG    B ARG A 1 238 ? 11.80802  3.56567   -2.48253  0.441 24.73869  ? 1244 ARG A CG    1 
ATOM   2061 C CD    A ARG A 1 238 ? 9.12145   -0.29138  -5.95929  0.559 45.90011  ? 1244 ARG A CD    1 
ATOM   2062 C CD    B ARG A 1 238 ? 12.95582  2.78516   -3.09826  0.441 45.93046  ? 1244 ARG A CD    1 
ATOM   2063 N NE    A ARG A 1 238 ? 9.05260   0.86311   -6.84593  0.559 64.25266  ? 1244 ARG A NE    1 
ATOM   2064 N NE    B ARG A 1 238 ? 14.23462  3.19360   -2.52927  0.441 40.97342  ? 1244 ARG A NE    1 
ATOM   2065 C CZ    A ARG A 1 238 ? 9.37694   0.84100   -8.13101  0.559 46.57642  ? 1244 ARG A CZ    1 
ATOM   2066 C CZ    B ARG A 1 238 ? 15.35129  2.48213   -2.59933  0.441 66.52825  ? 1244 ARG A CZ    1 
ATOM   2067 N NH1   A ARG A 1 238 ? 9.82500   -0.25991  -8.71190  0.559 62.12974  ? 1244 ARG A NH1   1 
ATOM   2068 N NH1   B ARG A 1 238 ? 15.39785  1.32959   -3.24739  0.441 38.17220  ? 1244 ARG A NH1   1 
ATOM   2069 N NH2   A ARG A 1 238 ? 9.24892   1.95153   -8.85132  0.559 59.67928  ? 1244 ARG A NH2   1 
ATOM   2070 N NH2   B ARG A 1 238 ? 16.45008  2.94033   -2.00646  0.441 37.79484  ? 1244 ARG A NH2   1 
ATOM   2071 N N     A SER A 1 239 ? 4.71229   -0.33795  -4.15916  0.559 24.56578  ? 1245 SER A N     1 
ATOM   2072 N N     B SER A 1 239 ? 7.23887   2.74861   -3.59810  0.441 23.86251  ? 1245 SER A N     1 
ATOM   2073 C CA    A SER A 1 239 ? 3.40808   -0.70574  -4.69465  0.559 26.60758  ? 1245 SER A CA    1 
ATOM   2074 C CA    B SER A 1 239 ? 6.00656   2.87603   -4.36062  0.441 24.20344  ? 1245 SER A CA    1 
ATOM   2075 C C     A SER A 1 239 ? 2.32571   -0.70782  -3.62025  0.559 27.46065  ? 1245 SER A C     1 
ATOM   2076 C C     B SER A 1 239 ? 4.86783   3.43327   -3.52247  0.441 23.21587  ? 1245 SER A C     1 
ATOM   2077 O O     A SER A 1 239 ? 1.34594   -1.45493  -3.72267  0.559 30.14848  ? 1245 SER A O     1 
ATOM   2078 O O     B SER A 1 239 ? 3.89526   3.94192   -4.08612  0.441 24.53782  ? 1245 SER A O     1 
ATOM   2079 C CB    A SER A 1 239 ? 3.46709   -2.04894  -5.42023  0.559 27.32655  ? 1245 SER A CB    1 
ATOM   2080 C CB    B SER A 1 239 ? 5.59727   1.51427   -4.92345  0.441 25.07310  ? 1245 SER A CB    1 
ATOM   2081 O OG    A SER A 1 239 ? 4.41442   -2.00992  -6.47007  0.559 27.58290  ? 1245 SER A OG    1 
ATOM   2082 O OG    B SER A 1 239 ? 6.54126   1.05060   -5.87208  0.441 25.80766  ? 1245 SER A OG    1 
ATOM   2083 N N     A GLY A 1 240 ? 2.49717   0.10993   -2.58273  0.559 25.19229  ? 1246 GLY A N     1 
ATOM   2084 N N     B GLY A 1 240 ? 4.97266   3.35519   -2.19631  0.441 21.04004  ? 1246 GLY A N     1 
ATOM   2085 C CA    A GLY A 1 240 ? 1.44521   0.42860   -1.63616  0.559 23.41147  ? 1246 GLY A CA    1 
ATOM   2086 C CA    B GLY A 1 240 ? 3.92657   3.80046   -1.29928  0.441 19.62118  ? 1246 GLY A CA    1 
ATOM   2087 C C     A GLY A 1 240 ? 0.88779   -0.69038  -0.78600  0.559 21.68968  ? 1246 GLY A C     1 
ATOM   2088 C C     B GLY A 1 240 ? 3.14745   2.68807   -0.63580  0.441 19.61992  ? 1246 GLY A C     1 
ATOM   2089 O O     A GLY A 1 240 ? -0.03754  -0.46200  -0.00249  0.559 21.59200  ? 1246 GLY A O     1 
ATOM   2090 O O     B GLY A 1 240 ? 2.22512   2.98023   0.13324   0.441 19.43777  ? 1246 GLY A O     1 
ATOM   2091 N N     A GLY A 1 241 ? 1.41538   -1.89796  -0.93083  0.559 19.89740  ? 1247 GLY A N     1 
ATOM   2092 N N     B GLY A 1 241 ? 3.46788   1.42293   -0.91922  0.441 19.08563  ? 1247 GLY A N     1 
ATOM   2093 C CA    A GLY A 1 241 ? 1.10220   -2.94550  0.01522   0.559 18.74810  ? 1247 GLY A CA    1 
ATOM   2094 C CA    B GLY A 1 241 ? 2.84105   0.30625   -0.24521  0.441 18.91662  ? 1247 GLY A CA    1 
ATOM   2095 C C     A GLY A 1 241 ? 1.82354   -2.72181  1.32736   0.559 17.76445  ? 1247 GLY A C     1 
ATOM   2096 C C     B GLY A 1 241 ? 3.54803   -0.04239  1.05358   0.441 17.99630  ? 1247 GLY A C     1 
ATOM   2097 O O     A GLY A 1 241 ? 2.68756   -1.85489  1.46324   0.559 17.87446  ? 1247 GLY A O     1 
ATOM   2098 O O     B GLY A 1 241 ? 4.57687   0.52786   1.40789   0.441 17.39645  ? 1247 GLY A O     1 
ATOM   2099 N N     A LYS A 1 242 ? 1.45160   -3.51862  2.32307   0.559 16.62975  ? 1248 LYS A N     1 
ATOM   2100 N N     B LYS A 1 242 ? 2.96768   -1.00182  1.77388   0.441 17.09204  ? 1248 LYS A N     1 
ATOM   2101 C CA    A LYS A 1 242 ? 2.22592   -3.54401  3.55473   0.559 15.86610  ? 1248 LYS A CA    1 
ATOM   2102 C CA    B LYS A 1 242 ? 3.55479   -1.45418  3.02919   0.441 16.50597  ? 1248 LYS A CA    1 
ATOM   2103 C C     A LYS A 1 242 ? 3.66162   -3.95240  3.24246   0.559 15.03780  ? 1248 LYS A C     1 
ATOM   2104 C C     B LYS A 1 242 ? 4.94255   -2.03168  2.78117   0.441 16.39156  ? 1248 LYS A C     1 
ATOM   2105 O O     A LYS A 1 242 ? 3.91389   -4.76247  2.34612   0.559 15.41536  ? 1248 LYS A O     1 
ATOM   2106 O O     B LYS A 1 242 ? 5.17775   -2.71955  1.78480   0.441 17.16213  ? 1248 LYS A O     1 
ATOM   2107 C CB    A LYS A 1 242 ? 1.59942   -4.52037  4.55049   0.559 16.03723  ? 1248 LYS A CB    1 
ATOM   2108 C CB    B LYS A 1 242 ? 2.65938   -2.51608  3.67196   0.441 17.41865  ? 1248 LYS A CB    1 
ATOM   2109 C CG    A LYS A 1 242 ? 0.21870   -4.10653  5.03930   0.559 26.26018  ? 1248 LYS A CG    1 
ATOM   2110 C CG    B LYS A 1 242 ? 1.31588   -1.98999  4.14742   0.441 23.56682  ? 1248 LYS A CG    1 
ATOM   2111 C CD    A LYS A 1 242 ? -0.44766  -5.21635  5.83945   0.559 30.21045  ? 1248 LYS A CD    1 
ATOM   2112 C CD    B LYS A 1 242 ? 0.46962   -3.07763  4.78897   0.441 42.38383  ? 1248 LYS A CD    1 
ATOM   2113 C CE    A LYS A 1 242 ? 0.33383   -5.52800  7.10641   0.559 48.16198  ? 1248 LYS A CE    1 
ATOM   2114 C CE    B LYS A 1 242 ? -0.86222  -2.51434  5.26572   0.441 76.29672  ? 1248 LYS A CE    1 
ATOM   2115 N NZ    A LYS A 1 242 ? -0.46062  -6.34662  8.06363   0.559 67.41994  ? 1248 LYS A NZ    1 
ATOM   2116 N NZ    B LYS A 1 242 ? -1.72705  -3.54948  5.89488   0.441 63.03082  ? 1248 LYS A NZ    1 
ATOM   2117 N N     A MET A 1 243 ? 4.61055   -3.36919  3.97225   0.559 13.66031  ? 1249 MET A N     1 
ATOM   2118 N N     B MET A 1 243 ? 5.86813   -1.73918  3.68932   0.441 15.46809  ? 1249 MET A N     1 
ATOM   2119 C CA    A MET A 1 243 ? 6.02920   -3.60539  3.71513   0.559 13.42904  ? 1249 MET A CA    1 
ATOM   2120 C CA    B MET A 1 243 ? 7.24203   -2.21371  3.55787   0.441 14.68470  ? 1249 MET A CA    1 
ATOM   2121 C C     A MET A 1 243 ? 6.43087   -4.96209  4.27975   0.559 12.63727  ? 1249 MET A C     1 
ATOM   2122 C C     B MET A 1 243 ? 7.32322   -3.62242  4.12600   0.441 13.98396  ? 1249 MET A C     1 
ATOM   2123 O O     A MET A 1 243 ? 6.46827   -5.15212  5.50041   0.559 13.03623  ? 1249 MET A O     1 
ATOM   2124 O O     B MET A 1 243 ? 7.32386   -3.81752  5.34308   0.441 14.49100  ? 1249 MET A O     1 
ATOM   2125 C CB    A MET A 1 243 ? 6.87476   -2.49272  4.32634   0.559 14.22471  ? 1249 MET A CB    1 
ATOM   2126 C CB    B MET A 1 243 ? 8.20025   -1.28615  4.29278   0.441 15.60488  ? 1249 MET A CB    1 
ATOM   2127 C CG    A MET A 1 243 ? 8.36018   -2.58430  3.99732   0.559 14.97646  ? 1249 MET A CG    1 
ATOM   2128 C CG    B MET A 1 243 ? 9.66514   -1.66614  4.13141   0.441 16.41348  ? 1249 MET A CG    1 
ATOM   2129 S SD    A MET A 1 243 ? 8.72181   -2.06717  2.31174   0.559 17.01729  ? 1249 MET A SD    1 
ATOM   2130 S SD    B MET A 1 243 ? 10.36245  -1.21988  2.52968   0.441 18.33988  ? 1249 MET A SD    1 
ATOM   2131 C CE    A MET A 1 243 ? 10.36279  -1.37395  2.48943   0.559 18.58258  ? 1249 MET A CE    1 
ATOM   2132 C CE    B MET A 1 243 ? 10.77047  0.49374   2.85129   0.441 17.46925  ? 1249 MET A CE    1 
ATOM   2133 N N     A TYR A 1 244 ? 6.75019   -5.90051  3.39770   0.559 12.85356  ? 1250 TYR A N     1 
ATOM   2134 N N     B TYR A 1 244 ? 7.38282   -4.61225  3.24679   0.441 13.73353  ? 1250 TYR A N     1 
ATOM   2135 C CA    A TYR A 1 244 ? 7.20707   -7.22423  3.78691   0.559 12.90306  ? 1250 TYR A CA    1 
ATOM   2136 C CA    B TYR A 1 244 ? 7.66344   -5.98062  3.64308   0.441 13.76465  ? 1250 TYR A CA    1 
ATOM   2137 C C     A TYR A 1 244 ? 8.67921   -7.38888  3.43127   0.559 12.72343  ? 1250 TYR A C     1 
ATOM   2138 C C     B TYR A 1 244 ? 9.12751   -6.28932  3.36492   0.441 12.45520  ? 1250 TYR A C     1 
ATOM   2139 O O     A TYR A 1 244 ? 9.27066   -6.57031  2.71972   0.559 12.71481  ? 1250 TYR A O     1 
ATOM   2140 O O     B TYR A 1 244 ? 9.83551   -5.52560  2.70463   0.441 12.36423  ? 1250 TYR A O     1 
ATOM   2141 C CB    A TYR A 1 244 ? 6.34521   -8.30782  3.13036   0.559 14.49125  ? 1250 TYR A CB    1 
ATOM   2142 C CB    B TYR A 1 244 ? 6.74692   -6.95914  2.90664   0.441 15.08625  ? 1250 TYR A CB    1 
ATOM   2143 C CG    A TYR A 1 244 ? 4.92625   -8.34355  3.65840   0.559 15.64640  ? 1250 TYR A CG    1 
ATOM   2144 C CG    B TYR A 1 244 ? 5.29259   -6.78973  3.26499   0.441 16.49925  ? 1250 TYR A CG    1 
ATOM   2145 C CD1   A TYR A 1 244 ? 4.66802   -8.57957  5.00560   0.559 16.38335  ? 1250 TYR A CD1   1 
ATOM   2146 C CD1   B TYR A 1 244 ? 4.80377   -7.23028  4.48556   0.441 17.66750  ? 1250 TYR A CD1   1 
ATOM   2147 C CD2   A TYR A 1 244 ? 3.84456   -8.12934  2.81385   0.559 16.84767  ? 1250 TYR A CD2   1 
ATOM   2148 C CD2   B TYR A 1 244 ? 4.40806   -6.18444  2.38563   0.441 17.78284  ? 1250 TYR A CD2   1 
ATOM   2149 C CE1   A TYR A 1 244 ? 3.37284   -8.60953  5.49396   0.559 17.95532  ? 1250 TYR A CE1   1 
ATOM   2150 C CE1   B TYR A 1 244 ? 3.47047   -7.07577  4.82098   0.441 18.91026  ? 1250 TYR A CE1   1 
ATOM   2151 C CE2   A TYR A 1 244 ? 2.54591   -8.15648  3.29221   0.559 17.97298  ? 1250 TYR A CE2   1 
ATOM   2152 C CE2   B TYR A 1 244 ? 3.07365   -6.02520  2.70951   0.441 18.89575  ? 1250 TYR A CE2   1 
ATOM   2153 C CZ    A TYR A 1 244 ? 2.31568   -8.39639  4.63204   0.559 18.78184  ? 1250 TYR A CZ    1 
ATOM   2154 C CZ    B TYR A 1 244 ? 2.60932   -6.47267  3.92748   0.441 19.94634  ? 1250 TYR A CZ    1 
ATOM   2155 O OH    A TYR A 1 244 ? 1.02256   -8.42238  5.10636   0.559 19.92362  ? 1250 TYR A OH    1 
ATOM   2156 O OH    B TYR A 1 244 ? 1.27916   -6.31213  4.24707   0.441 21.24199  ? 1250 TYR A OH    1 
ATOM   2157 N N     A VAL A 1 245 ? 9.27335   -8.46718  3.94665   0.559 12.23691  ? 1251 VAL A N     1 
ATOM   2158 N N     B VAL A 1 245 ? 9.59054   -7.41955  3.90292   0.441 11.38225  ? 1251 VAL A N     1 
ATOM   2159 C CA    A VAL A 1 245 ? 10.71205  -8.65287  3.79478   0.559 12.21162  ? 1251 VAL A CA    1 
ATOM   2160 C CA    B VAL A 1 245 ? 11.00649  -7.74832  3.77153   0.441 11.36760  ? 1251 VAL A CA    1 
ATOM   2161 C C     A VAL A 1 245 ? 11.11387  -8.73234  2.32426   0.559 12.19125  ? 1251 VAL A C     1 
ATOM   2162 C C     B VAL A 1 245 ? 11.40662  -7.86850  2.30494   0.441 10.92401  ? 1251 VAL A C     1 
ATOM   2163 O O     A VAL A 1 245 ? 12.18952  -8.25506  1.94336   0.559 12.96545  ? 1251 VAL A O     1 
ATOM   2164 O O     B VAL A 1 245 ? 12.52190  -7.48951  1.92999   0.441 11.31487  ? 1251 VAL A O     1 
ATOM   2165 C CB    A VAL A 1 245 ? 11.20483  -9.84590  4.64157   0.559 11.91961  ? 1251 VAL A CB    1 
ATOM   2166 C CB    B VAL A 1 245 ? 11.39511  -8.97788  4.62215   0.441 11.65049  ? 1251 VAL A CB    1 
ATOM   2167 C CG1   A VAL A 1 245 ? 10.79745  -11.16963 4.02009   0.559 11.45686  ? 1251 VAL A CG1   1 
ATOM   2168 C CG1   B VAL A 1 245 ? 10.92165  -10.26798 3.97014   0.441 12.31154  ? 1251 VAL A CG1   1 
ATOM   2169 C CG2   A VAL A 1 245 ? 12.71230  -9.76887  4.85549   0.559 12.52382  ? 1251 VAL A CG2   1 
ATOM   2170 C CG2   B VAL A 1 245 ? 12.89657  -9.00102  4.85963   0.441 11.20796  ? 1251 VAL A CG2   1 
ATOM   2171 N N     A GLN A 1 246 ? 10.24863  -9.28077  1.46490   0.559 11.90288  ? 1252 GLN A N     1 
ATOM   2172 N N     B GLN A 1 246 ? 10.49844  -8.35024  1.44651   0.441 11.24402  ? 1252 GLN A N     1 
ATOM   2173 C CA    A GLN A 1 246 ? 10.59372  -9.35061  0.04629   0.559 12.25301  ? 1252 GLN A CA    1 
ATOM   2174 C CA    B GLN A 1 246 ? 10.81889  -8.46194  0.02611   0.441 12.14920  ? 1252 GLN A CA    1 
ATOM   2175 C C     A GLN A 1 246 ? 10.70557  -7.96632  -0.57391  0.559 11.98293  ? 1252 GLN A C     1 
ATOM   2176 C C     B GLN A 1 246 ? 10.98605  -7.09159  -0.61643  0.441 12.39927  ? 1252 GLN A C     1 
ATOM   2177 O O     A GLN A 1 246 ? 11.47471  -7.76910  -1.52465  0.559 12.45352  ? 1252 GLN A O     1 
ATOM   2178 O O     B GLN A 1 246 ? 11.82396  -6.91907  -1.51139  0.441 12.56525  ? 1252 GLN A O     1 
ATOM   2179 C CB    A GLN A 1 246 ? 9.57202   -10.18921 -0.72274  0.559 12.29676  ? 1252 GLN A CB    1 
ATOM   2180 C CB    B GLN A 1 246 ? 9.75314   -9.27345  -0.71067  0.441 11.71378  ? 1252 GLN A CB    1 
ATOM   2181 C CG    A GLN A 1 246 ? 8.13948   -9.68411  -0.66637  0.559 12.99548  ? 1252 GLN A CG    1 
ATOM   2182 C CG    B GLN A 1 246 ? 8.34253   -8.71870  -0.60207  0.441 11.23372  ? 1252 GLN A CG    1 
ATOM   2183 C CD    A GLN A 1 246 ? 7.34820   -10.33904 0.44618   0.559 13.28880  ? 1252 GLN A CD    1 
ATOM   2184 C CD    B GLN A 1 246 ? 7.57369   -9.31692  0.55724   0.441 12.01141  ? 1252 GLN A CD    1 
ATOM   2185 O OE1   A GLN A 1 246 ? 7.91188   -10.73182 1.46555   0.559 13.16541  ? 1252 GLN A OE1   1 
ATOM   2186 O OE1   B GLN A 1 246 ? 8.15561   -9.72510  1.56225   0.441 12.44407  ? 1252 GLN A OE1   1 
ATOM   2187 N NE2   A GLN A 1 246 ? 6.03954   -10.46617 0.25424   0.559 13.39503  ? 1252 GLN A NE2   1 
ATOM   2188 N NE2   B GLN A 1 246 ? 6.25675   -9.37845  0.41959   0.441 12.82892  ? 1252 GLN A NE2   1 
ATOM   2189 N N     A ASP A 1 247 ? 9.93297   -7.00406  -0.06480  0.559 11.45334  ? 1253 ASP A N     1 
ATOM   2190 N N     B ASP A 1 247 ? 10.17971  -6.10966  -0.19843  0.441 13.74687  ? 1253 ASP A N     1 
ATOM   2191 C CA    A ASP A 1 247 ? 10.01023  -5.64145  -0.57752  0.559 12.51757  ? 1253 ASP A CA    1 
ATOM   2192 C CA    B ASP A 1 247 ? 10.40676  -4.75033  -0.67012  0.441 15.16193  ? 1253 ASP A CA    1 
ATOM   2193 C C     A ASP A 1 247 ? 11.34885  -4.98665  -0.25974  0.559 13.98894  ? 1253 ASP A C     1 
ATOM   2194 C C     B ASP A 1 247 ? 11.78919  -4.28815  -0.27153  0.441 16.20488  ? 1253 ASP A C     1 
ATOM   2195 O O     A ASP A 1 247 ? 11.85159  -4.19407  -1.06198  0.559 13.54651  ? 1253 ASP A O     1 
ATOM   2196 O O     B ASP A 1 247 ? 12.43165  -3.52744  -1.00324  0.441 15.50452  ? 1253 ASP A O     1 
ATOM   2197 C CB    A ASP A 1 247 ? 8.86037   -4.80741  -0.01859  0.559 12.13812  ? 1253 ASP A CB    1 
ATOM   2198 C CB    B ASP A 1 247 ? 9.35429   -3.80285  -0.10092  0.441 15.82923  ? 1253 ASP A CB    1 
ATOM   2199 C CG    A ASP A 1 247 ? 7.50538   -5.38278  -0.35923  0.559 13.47576  ? 1253 ASP A CG    1 
ATOM   2200 C CG    B ASP A 1 247 ? 7.95818   -4.18924  -0.50487  0.441 17.03224  ? 1253 ASP A CG    1 
ATOM   2201 O OD1   A ASP A 1 247 ? 7.28847   -5.72204  -1.54354  0.559 14.60418  ? 1253 ASP A OD1   1 
ATOM   2202 O OD1   B ASP A 1 247 ? 7.69141   -4.23998  -1.72280  0.441 18.55539  ? 1253 ASP A OD1   1 
ATOM   2203 O OD2   A ASP A 1 247 ? 6.65119   -5.46799  0.54623   0.559 13.45570  ? 1253 ASP A OD2   1 
ATOM   2204 O OD2   B ASP A 1 247 ? 7.13446   -4.45395  0.39245   0.441 18.81180  ? 1253 ASP A OD2   1 
ATOM   2205 N N     A LYS A 1 248 ? 11.93262  -5.29797  0.90153   0.559 15.96389  ? 1254 LYS A N     1 
ATOM   2206 N N     B LYS A 1 248 ? 12.26991  -4.76199  0.87600   0.441 18.76660  ? 1254 LYS A N     1 
ATOM   2207 C CA    A LYS A 1 248 ? 13.21884  -4.71128  1.28454   0.559 18.48502  ? 1254 LYS A CA    1 
ATOM   2208 C CA    B LYS A 1 248 ? 13.63086  -4.45320  1.27151   0.441 19.54481  ? 1254 LYS A CA    1 
ATOM   2209 C C     A LYS A 1 248 ? 14.35059  -5.22737  0.40030   0.559 18.71979  ? 1254 LYS A C     1 
ATOM   2210 C C     B LYS A 1 248 ? 14.63594  -5.25381  0.45151   0.441 19.26133  ? 1254 LYS A C     1 
ATOM   2211 O O     A LYS A 1 248 ? 15.23235  -4.46512  -0.01302  0.559 18.87838  ? 1254 LYS A O     1 
ATOM   2212 O O     B LYS A 1 248 ? 15.66661  -4.70471  0.04228   0.441 19.43815  ? 1254 LYS A O     1 
ATOM   2213 C CB    A LYS A 1 248 ? 13.50782  -5.05635  2.74580   0.559 21.47398  ? 1254 LYS A CB    1 
ATOM   2214 C CB    B LYS A 1 248 ? 13.80462  -4.63244  2.77758   0.441 19.88956  ? 1254 LYS A CB    1 
ATOM   2215 C CG    A LYS A 1 248 ? 14.67510  -4.31196  3.38022   0.559 24.19646  ? 1254 LYS A CG    1 
ATOM   2216 C CG    B LYS A 1 248 ? 13.37502  -3.38670  3.55152   0.441 20.49707  ? 1254 LYS A CG    1 
ATOM   2217 C CD    A LYS A 1 248 ? 14.71203  -2.84733  3.00635   0.559 26.22651  ? 1254 LYS A CD    1 
ATOM   2218 C CD    B LYS A 1 248 ? 14.48075  -2.33882  3.61735   0.441 19.98297  ? 1254 LYS A CD    1 
ATOM   2219 C CE    A LYS A 1 248 ? 13.92579  -2.03952  4.01696   0.559 26.31955  ? 1254 LYS A CE    1 
ATOM   2220 C CE    B LYS A 1 248 ? 13.93902  -0.99084  4.07353   0.441 17.68787  ? 1254 LYS A CE    1 
ATOM   2221 N NZ    A LYS A 1 248 ? 13.83411  -0.60641  3.66057   0.559 26.43016  ? 1254 LYS A NZ    1 
ATOM   2222 N NZ    B LYS A 1 248 ? 14.86759  0.12855   3.75314   0.441 17.33100  ? 1254 LYS A NZ    1 
ATOM   2223 N N     . ILE A 1 249 ? 14.35321  -6.53346  0.14982   1.000 18.78861  ? 1255 ILE A N     1 
ATOM   2224 C CA    . ILE A 1 249 ? 15.24403  -7.19739  -0.80355  1.000 18.91532  ? 1255 ILE A CA    1 
ATOM   2225 C C     . ILE A 1 249 ? 15.24072  -6.45717  -2.13135  1.000 18.91298  ? 1255 ILE A C     1 
ATOM   2226 O O     . ILE A 1 249 ? 16.29018  -6.24276  -2.74667  1.000 18.29824  ? 1255 ILE A O     1 
ATOM   2227 C CB    . ILE A 1 249 ? 14.84229  -8.67222  -0.98907  1.000 17.82004  ? 1255 ILE A CB    1 
ATOM   2228 C CG1   . ILE A 1 249 ? 15.00869  -9.44829  0.31732   1.000 17.92345  ? 1255 ILE A CG1   1 
ATOM   2229 C CG2   . ILE A 1 249 ? 15.66719  -9.32077  -2.09448  1.000 18.91286  ? 1255 ILE A CG2   1 
ATOM   2230 C CD1   . ILE A 1 249 ? 14.48146  -10.85311 0.24018   1.000 17.83730  ? 1255 ILE A CD1   1 
ATOM   2231 N N     . GLU A 1 250 ? 14.05977  -6.03284  -2.57953  1.000 19.15459  ? 1256 GLU A N     1 
ATOM   2232 C CA    . GLU A 1 250 ? 13.94406  -5.39263  -3.88311  1.000 19.94370  ? 1256 GLU A CA    1 
ATOM   2233 C C     . GLU A 1 250 ? 14.63874  -4.03502  -3.91636  1.000 19.93329  ? 1256 GLU A C     1 
ATOM   2234 O O     . GLU A 1 250 ? 15.15641  -3.63801  -4.96648  1.000 20.18835  ? 1256 GLU A O     1 
ATOM   2235 C CB    . GLU A 1 250 ? 12.46910  -5.27519  -4.26671  1.000 20.75206  ? 1256 GLU A CB    1 
ATOM   2236 C CG    . GLU A 1 250 ? 12.22827  -4.71316  -5.66707  1.000 22.71406  ? 1256 GLU A CG    1 
ATOM   2237 C CD    . GLU A 1 250 ? 10.80304  -4.23203  -5.88865  1.000 26.53856  ? 1256 GLU A CD    1 
ATOM   2238 O OE1   . GLU A 1 250 ? 10.59233  -3.31205  -6.71549  1.000 29.07358  ? 1256 GLU A OE1   1 
ATOM   2239 O OE2   . GLU A 1 250 ? 9.88941   -4.77146  -5.23139  1.000 27.85304  ? 1256 GLU A OE2   1 
ATOM   2240 N N     . GLU A 1 251 ? 14.65644  -3.30782  -2.79241  1.000 20.73059  ? 1257 GLU A N     1 
ATOM   2241 C CA    . GLU A 1 251 ? 15.44104  -2.07631  -2.70286  1.000 21.24866  ? 1257 GLU A CA    1 
ATOM   2242 C C     . GLU A 1 251 ? 16.91079  -2.29855  -3.01723  1.000 20.31275  ? 1257 GLU A C     1 
ATOM   2243 O O     . GLU A 1 251 ? 17.59324  -1.35486  -3.43368  1.000 21.90286  ? 1257 GLU A O     1 
ATOM   2244 C CB    . GLU A 1 251 ? 15.31826  -1.44288  -1.31314  1.000 23.17658  ? 1257 GLU A CB    1 
ATOM   2245 C CG    . GLU A 1 251 ? 13.93878  -0.95858  -0.95313  1.000 25.20003  ? 1257 GLU A CG    1 
ATOM   2246 C CD    . GLU A 1 251 ? 13.93314  -0.06181  0.27244   1.000 27.42486  ? 1257 GLU A CD    1 
ATOM   2247 O OE1   . GLU A 1 251 ? 14.98710  0.08010   0.93783   1.000 28.23963  ? 1257 GLU A OE1   1 
ATOM   2248 O OE2   . GLU A 1 251 ? 12.86523  0.50336   0.57340   1.000 29.69281  ? 1257 GLU A OE2   1 
ATOM   2249 N N     . TYR A 1 252 ? 17.41307  -3.51677  -2.82577  1.000 17.91630  ? 1258 TYR A N     1 
ATOM   2250 C CA    . TYR A 1 252 ? 18.79784  -3.85877  -3.11653  1.000 16.48901  ? 1258 TYR A CA    1 
ATOM   2251 C C     . TYR A 1 252 ? 18.88658  -4.91170  -4.21514  1.000 15.35617  ? 1258 TYR A C     1 
ATOM   2252 O O     . TYR A 1 252 ? 19.80160  -5.73223  -4.20311  1.000 15.02390  ? 1258 TYR A O     1 
ATOM   2253 C CB    . TYR A 1 252 ? 19.51506  -4.34434  -1.85902  1.000 16.05672  ? 1258 TYR A CB    1 
ATOM   2254 C CG    . TYR A 1 252 ? 19.50074  -3.36341  -0.71581  1.000 15.93531  ? 1258 TYR A CG    1 
ATOM   2255 C CD1   . TYR A 1 252 ? 20.46428  -2.37139  -0.62413  1.000 16.37058  ? 1258 TYR A CD1   1 
ATOM   2256 C CD2   . TYR A 1 252 ? 18.52784  -3.43018  0.27085   1.000 16.34440  ? 1258 TYR A CD2   1 
ATOM   2257 C CE1   . TYR A 1 252 ? 20.47538  -1.48111  0.43515   1.000 16.89507  ? 1258 TYR A CE1   1 
ATOM   2258 C CE2   . TYR A 1 252 ? 18.52257  -2.54006  1.33088   1.000 16.80405  ? 1258 TYR A CE2   1 
ATOM   2259 C CZ    . TYR A 1 252 ? 19.49696  -1.56405  1.41003   1.000 16.59920  ? 1258 TYR A CZ    1 
ATOM   2260 O OH    . TYR A 1 252 ? 19.50612  -0.67528  2.46614   1.000 17.06202  ? 1258 TYR A OH    1 
ATOM   2261 N N     . SER A 1 253 ? 17.95661  -4.86556  -5.18029  1.000 15.10455  ? 1259 SER A N     1 
ATOM   2262 C CA    A SER A 1 253 ? 17.83850  -5.94947  -6.15096  0.621 15.72490  ? 1259 SER A CA    1 
ATOM   2263 C CA    B SER A 1 253 ? 17.82679  -5.91848  -6.19164  0.379 15.22307  ? 1259 SER A CA    1 
ATOM   2264 C C     . SER A 1 253 ? 19.15653  -6.20541  -6.87402  1.000 14.14791  ? 1259 SER A C     1 
ATOM   2265 O O     . SER A 1 253 ? 19.57373  -7.36254  -7.02380  1.000 13.85731  ? 1259 SER A O     1 
ATOM   2266 C CB    A SER A 1 253 ? 16.71441  -5.65332  -7.14551  0.621 17.27872  ? 1259 SER A CB    1 
ATOM   2267 C CB    B SER A 1 253 ? 16.81510  -5.48212  -7.26095  0.379 15.88614  ? 1259 SER A CB    1 
ATOM   2268 O OG    A SER A 1 253 ? 17.02396  -4.51611  -7.92110  0.621 19.10064  ? 1259 SER A OG    1 
ATOM   2269 O OG    B SER A 1 253 ? 15.47392  -5.52809  -6.81038  0.379 16.51301  ? 1259 SER A OG    1 
ATOM   2270 N N     . ASP A 1 254 ? 19.81153  -5.14961  -7.35019  1.000 14.24028  ? 1260 ASP A N     1 
ATOM   2271 C CA    . ASP A 1 254 ? 21.03734  -5.33015  -8.11868  1.000 13.98313  ? 1260 ASP A CA    1 
ATOM   2272 C C     . ASP A 1 254 ? 22.15935  -5.87722  -7.25447  1.000 13.55090  ? 1260 ASP A C     1 
ATOM   2273 O O     . ASP A 1 254 ? 22.84013  -6.83513  -7.63694  1.000 13.39721  ? 1260 ASP A O     1 
ATOM   2274 C CB    . ASP A 1 254 ? 21.42948  -4.01562  -8.79433  1.000 15.11653  ? 1260 ASP A CB    1 
ATOM   2275 C CG    . ASP A 1 254 ? 22.47091  -4.20543  -9.87811  1.000 16.96124  ? 1260 ASP A CG    1 
ATOM   2276 O OD1   . ASP A 1 254 ? 22.48353  -5.26861  -10.53472 1.000 18.41397  ? 1260 ASP A OD1   1 
ATOM   2277 O OD2   . ASP A 1 254 ? 23.24385  -3.25613  -10.13289 1.000 21.18142  ? 1260 ASP A OD2   1 
ATOM   2278 N N     . GLU A 1 255 ? 22.37260  -5.28016  -6.08277  1.000 13.91606  ? 1261 GLU A N     1 
ATOM   2279 C CA    . GLU A 1 255 ? 23.41281  -5.79701  -5.19958  1.000 14.00150  ? 1261 GLU A CA    1 
ATOM   2280 C C     . GLU A 1 255 ? 23.16575  -7.25439  -4.84233  1.000 12.93989  ? 1261 GLU A C     1 
ATOM   2281 O O     . GLU A 1 255 ? 24.10073  -8.06264  -4.83731  1.000 12.76391  ? 1261 GLU A O     1 
ATOM   2282 C CB    . GLU A 1 255 ? 23.54823  -4.96584  -3.92864  1.000 15.22700  ? 1261 GLU A CB    1 
ATOM   2283 C CG    . GLU A 1 255 ? 23.91970  -3.52757  -4.14807  1.000 16.49289  ? 1261 GLU A CG    1 
ATOM   2284 C CD    . GLU A 1 255 ? 24.30679  -2.86463  -2.84416  1.000 18.89752  ? 1261 GLU A CD    1 
ATOM   2285 O OE1   . GLU A 1 255 ? 25.43578  -3.09653  -2.35069  1.000 21.74307  ? 1261 GLU A OE1   1 
ATOM   2286 O OE2   . GLU A 1 255 ? 23.45504  -2.17408  -2.25718  1.000 19.66434  ? 1261 GLU A OE2   1 
ATOM   2287 N N     . ILE A 1 256 ? 21.91642  -7.60915  -4.53572  1.000 12.58104  ? 1262 ILE A N     1 
ATOM   2288 C CA    . ILE A 1 256 ? 21.61281  -8.97210  -4.10295  1.000 12.72521  ? 1262 ILE A CA    1 
ATOM   2289 C C     . ILE A 1 256 ? 21.83031  -9.96484  -5.24089  1.000 12.26509  ? 1262 ILE A C     1 
ATOM   2290 O O     . ILE A 1 256 ? 22.44746  -11.02158 -5.05246  1.000 12.45240  ? 1262 ILE A O     1 
ATOM   2291 C CB    . ILE A 1 256 ? 20.18695  -9.04730  -3.52442  1.000 13.45680  ? 1262 ILE A CB    1 
ATOM   2292 C CG1   . ILE A 1 256 ? 20.09222  -8.28844  -2.19183  1.000 14.88861  ? 1262 ILE A CG1   1 
ATOM   2293 C CG2   . ILE A 1 256 ? 19.73286  -10.49189 -3.37276  1.000 13.45037  ? 1262 ILE A CG2   1 
ATOM   2294 C CD1   . ILE A 1 256 ? 20.80704  -8.94672  -1.03703  1.000 16.26186  ? 1262 ILE A CD1   1 
ATOM   2295 N N     . PHE A 1 257 ? 21.33130  -9.64793  -6.43887  1.000 12.73742  ? 1263 PHE A N     1 
ATOM   2296 C CA    . PHE A 1 257 ? 21.50463  -10.58309 -7.54554  1.000 12.17932  ? 1263 PHE A CA    1 
ATOM   2297 C C     . PHE A 1 257 ? 22.97795  -10.74693 -7.89560  1.000 12.10149  ? 1263 PHE A C     1 
ATOM   2298 O O     . PHE A 1 257 ? 23.43396  -11.85657 -8.19389  1.000 12.40996  ? 1263 PHE A O     1 
ATOM   2299 C CB    . PHE A 1 257 ? 20.66075  -10.16536 -8.75244  1.000 13.60563  ? 1263 PHE A CB    1 
ATOM   2300 C CG    . PHE A 1 257 ? 19.27375  -10.74235 -8.73590  1.000 14.14798  ? 1263 PHE A CG    1 
ATOM   2301 C CD1   . PHE A 1 257 ? 18.48963  -10.65769 -7.59847  1.000 16.00767  ? 1263 PHE A CD1   1 
ATOM   2302 C CD2   . PHE A 1 257 ? 18.75768  -11.39127 -9.84452  1.000 15.18975  ? 1263 PHE A CD2   1 
ATOM   2303 C CE1   . PHE A 1 257 ? 17.21684  -11.19803 -7.57286  1.000 17.49266  ? 1263 PHE A CE1   1 
ATOM   2304 C CE2   . PHE A 1 257 ? 17.48399  -11.93271 -9.82001  1.000 15.98752  ? 1263 PHE A CE2   1 
ATOM   2305 C CZ    . PHE A 1 257 ? 16.71301  -11.83092 -8.68769  1.000 16.68857  ? 1263 PHE A CZ    1 
ATOM   2306 N N     . LYS A 1 258 ? 23.74715  -9.65479  -7.85315  1.000 12.70580  ? 1264 LYS A N     1 
ATOM   2307 C CA    A LYS A 1 258 ? 25.18252  -9.77434  -8.07587  0.857 12.38864  ? 1264 LYS A CA    1 
ATOM   2308 C CA    B LYS A 1 258 ? 25.18666  -9.76506  -8.07058  0.143 12.31141  ? 1264 LYS A CA    1 
ATOM   2309 C C     . LYS A 1 258 ? 25.83759  -10.66138 -7.02273  1.000 11.83967  ? 1264 LYS A C     1 
ATOM   2310 O O     . LYS A 1 258 ? 26.70069  -11.48655 -7.34688  1.000 12.18132  ? 1264 LYS A O     1 
ATOM   2311 C CB    A LYS A 1 258 ? 25.83611  -8.39611  -8.11701  0.857 13.53817  ? 1264 LYS A CB    1 
ATOM   2312 C CB    B LYS A 1 258 ? 25.83238  -8.38006  -8.06476  0.143 12.57767  ? 1264 LYS A CB    1 
ATOM   2313 C CG    A LYS A 1 258 ? 25.65155  -7.66727  -9.44484  0.857 15.72183  ? 1264 LYS A CG    1 
ATOM   2314 C CG    B LYS A 1 258 ? 25.50655  -7.52369  -9.27693  0.143 12.98206  ? 1264 LYS A CG    1 
ATOM   2315 C CD    A LYS A 1 258 ? 26.06104  -6.20069  -9.35371  0.857 17.25033  ? 1264 LYS A CD    1 
ATOM   2316 C CD    B LYS A 1 258 ? 26.01101  -6.10220  -9.08227  0.143 13.27133  ? 1264 LYS A CD    1 
ATOM   2317 C CE    A LYS A 1 258 ? 26.29744  -5.58924  -10.73105 0.857 18.61056  ? 1264 LYS A CE    1 
ATOM   2318 C CE    B LYS A 1 258 ? 26.67833  -5.56187  -10.33631 0.143 13.36742  ? 1264 LYS A CE    1 
ATOM   2319 N NZ    A LYS A 1 258 ? 25.08814  -5.73236  -11.58695 0.857 20.12162  ? 1264 LYS A NZ    1 
ATOM   2320 N NZ    B LYS A 1 258 ? 25.96878  -4.35613  -10.84085 0.143 13.51818  ? 1264 LYS A NZ    1 
ATOM   2321 N N     . LEU A 1 259 ? 25.44561  -10.51019 -5.75266  1.000 11.59060  ? 1265 LEU A N     1 
ATOM   2322 C CA    . LEU A 1 259 ? 26.01823  -11.36787 -4.71704  1.000 11.44205  ? 1265 LEU A CA    1 
ATOM   2323 C C     . LEU A 1 259 ? 25.66711  -12.83460 -4.94945  1.000 11.09883  ? 1265 LEU A C     1 
ATOM   2324 O O     . LEU A 1 259 ? 26.52084  -13.71849 -4.78667  1.000 11.19311  ? 1265 LEU A O     1 
ATOM   2325 C CB    . LEU A 1 259 ? 25.54936  -10.92493 -3.33389  1.000 11.62417  ? 1265 LEU A CB    1 
ATOM   2326 C CG    . LEU A 1 259 ? 26.15265  -9.60780  -2.84741  1.000 12.34752  ? 1265 LEU A CG    1 
ATOM   2327 C CD1   . LEU A 1 259 ? 25.43958  -9.17320  -1.58041  1.000 12.87706  ? 1265 LEU A CD1   1 
ATOM   2328 C CD2   . LEU A 1 259 ? 27.65490  -9.72457  -2.59489  1.000 13.02535  ? 1265 LEU A CD2   1 
ATOM   2329 N N     . LEU A 1 260 ? 24.41145  -13.11524 -5.31373  1.000 11.26579  ? 1266 LEU A N     1 
ATOM   2330 C CA    . LEU A 1 260 ? 24.01824  -14.48941 -5.61384  1.000 11.08284  ? 1266 LEU A CA    1 
ATOM   2331 C C     . LEU A 1 260 ? 24.85295  -15.04757 -6.75553  1.000 11.17511  ? 1266 LEU A C     1 
ATOM   2332 O O     . LEU A 1 260 ? 25.35516  -16.17732 -6.68172  1.000 11.67611  ? 1266 LEU A O     1 
ATOM   2333 C CB    . LEU A 1 260 ? 22.52934  -14.55179 -5.94643  1.000 11.98409  ? 1266 LEU A CB    1 
ATOM   2334 C CG    . LEU A 1 260 ? 21.60281  -14.27779 -4.75765  1.000 12.56109  ? 1266 LEU A CG    1 
ATOM   2335 C CD1   . LEU A 1 260 ? 20.15241  -14.09536 -5.20165  1.000 13.83844  ? 1266 LEU A CD1   1 
ATOM   2336 C CD2   . LEU A 1 260 ? 21.69341  -15.38556 -3.69796  1.000 12.83637  ? 1266 LEU A CD2   1 
ATOM   2337 N N     . ASP A 1 261 ? 25.01561  -14.26244 -7.82357  1.000 12.03463  ? 1267 ASP A N     1 
ATOM   2338 C CA    . ASP A 1 261 ? 25.82022  -14.71191 -8.95103  1.000 12.85650  ? 1267 ASP A CA    1 
ATOM   2339 C C     . ASP A 1 261 ? 27.26440  -14.96270 -8.53166  1.000 12.72026  ? 1267 ASP A C     1 
ATOM   2340 O O     . ASP A 1 261 ? 27.93974  -15.81599 -9.11566  1.000 15.15736  ? 1267 ASP A O     1 
ATOM   2341 C CB    . ASP A 1 261 ? 25.77298  -13.64439 -10.03866 1.000 13.75746  ? 1267 ASP A CB    1 
ATOM   2342 C CG    . ASP A 1 261 ? 24.46685  -13.62888 -10.80288 1.000 14.94986  ? 1267 ASP A CG    1 
ATOM   2343 O OD1   . ASP A 1 261 ? 23.58212  -14.46896 -10.54210 1.000 16.03804  ? 1267 ASP A OD1   1 
ATOM   2344 O OD2   . ASP A 1 261 ? 24.30542  -12.70883 -11.63092 1.000 16.77008  ? 1267 ASP A OD2   1 
ATOM   2345 N N     . GLY A 1 262 ? 27.75433  -14.23315 -7.52789  1.000 12.67616  ? 1268 GLY A N     1 
ATOM   2346 C CA    . GLY A 1 262 ? 29.08985  -14.43535 -7.01612  1.000 13.27631  ? 1268 GLY A CA    1 
ATOM   2347 C C     . GLY A 1 262 ? 29.25051  -15.56915 -6.03355  1.000 12.74980  ? 1268 GLY A C     1 
ATOM   2348 O O     . GLY A 1 262 ? 30.36110  -15.78640 -5.54506  1.000 14.28058  ? 1268 GLY A O     1 
ATOM   2349 N N     . GLY A 1 263 ? 28.18543  -16.30351 -5.72865  1.000 11.76476  ? 1269 GLY A N     1 
ATOM   2350 C CA    . GLY A 1 263 ? 28.27372  -17.46035 -4.86245  1.000 11.67402  ? 1269 GLY A CA    1 
ATOM   2351 C C     . GLY A 1 263 ? 27.67760  -17.30963 -3.47558  1.000 10.81009  ? 1269 GLY A C     1 
ATOM   2352 O O     . GLY A 1 263 ? 27.85087  -18.21424 -2.65101  1.000 11.18684  ? 1269 GLY A O     1 
ATOM   2353 N N     . ALA A 1 264 ? 26.98021  -16.21599 -3.18994  1.000 10.58224  ? 1270 ALA A N     1 
ATOM   2354 C CA    . ALA A 1 264 ? 26.42209  -16.01444 -1.86036  1.000 10.18366  ? 1270 ALA A CA    1 
ATOM   2355 C C     . ALA A 1 264 ? 25.42080  -17.10441 -1.50578  1.000 9.68461   ? 1270 ALA A C     1 
ATOM   2356 O O     . ALA A 1 264 ? 24.66182  -17.58646 -2.35513  1.000 10.61445  ? 1270 ALA A O     1 
ATOM   2357 C CB    . ALA A 1 264 ? 25.72008  -14.65922 -1.79304  1.000 11.42552  ? 1270 ALA A CB    1 
ATOM   2358 N N     . HIS A 1 265 ? 25.41747  -17.47310 -0.22904  1.000 9.28409   ? 1271 HIS A N     1 
ATOM   2359 C CA    . HIS A 1 265 ? 24.34556  -18.26297 0.33852   1.000 9.29721   ? 1271 HIS A CA    1 
ATOM   2360 C C     . HIS A 1 265 ? 23.20004  -17.34806 0.71847   1.000 9.21085   ? 1271 HIS A C     1 
ATOM   2361 O O     . HIS A 1 265 ? 23.40549  -16.21782 1.16988   1.000 9.84726   ? 1271 HIS A O     1 
ATOM   2362 C CB    . HIS A 1 265 ? 24.84010  -18.96996 1.59346   1.000 9.78208   ? 1271 HIS A CB    1 
ATOM   2363 C CG    . HIS A 1 265 ? 25.83484  -20.02894 1.29047   1.000 10.20897  ? 1271 HIS A CG    1 
ATOM   2364 N ND1   . HIS A 1 265 ? 25.46091  -21.27779 0.84380   1.000 10.88067  ? 1271 HIS A ND1   1 
ATOM   2365 C CD2   . HIS A 1 265 ? 27.18883  -20.00280 1.27697   1.000 11.12038  ? 1271 HIS A CD2   1 
ATOM   2366 C CE1   . HIS A 1 265 ? 26.54798  -21.98763 0.59814   1.000 11.65531  ? 1271 HIS A CE1   1 
ATOM   2367 N NE2   . HIS A 1 265 ? 27.60745  -21.23872 0.85309   1.000 11.57515  ? 1271 HIS A NE2   1 
ATOM   2368 N N     . ILE A 1 266 ? 21.98415  -17.84915 0.55180   1.000 9.36280   ? 1272 ILE A N     1 
ATOM   2369 C CA    . ILE A 1 266 ? 20.80151  -17.11662 0.95943   1.000 9.55483   ? 1272 ILE A CA    1 
ATOM   2370 C C     . ILE A 1 266 ? 19.90841  -18.05237 1.76275   1.000 9.08871   ? 1272 ILE A C     1 
ATOM   2371 O O     . ILE A 1 266 ? 19.73467  -19.22711 1.41654   1.000 10.09239  ? 1272 ILE A O     1 
ATOM   2372 C CB    . ILE A 1 266 ? 20.08633  -16.44156 -0.23754  1.000 10.26013  ? 1272 ILE A CB    1 
ATOM   2373 C CG1   . ILE A 1 266 ? 18.95729  -15.53076 0.24380   1.000 10.60315  ? 1272 ILE A CG1   1 
ATOM   2374 C CG2   . ILE A 1 266 ? 19.61863  -17.45921 -1.28229  1.000 10.82084  ? 1272 ILE A CG2   1 
ATOM   2375 C CD1   . ILE A 1 266 ? 18.47458  -14.54697 -0.80280  1.000 12.08102  ? 1272 ILE A CD1   1 
ATOM   2376 N N     . TYR A 1 267 ? 19.37064  -17.53073 2.85595   1.000 9.27650   ? 1273 TYR A N     1 
ATOM   2377 C CA    . TYR A 1 267 ? 18.65033  -18.30626 3.85260   1.000 9.77661   ? 1273 TYR A CA    1 
ATOM   2378 C C     . TYR A 1 267 ? 17.29991  -17.66497 4.08880   1.000 10.03687  ? 1273 TYR A C     1 
ATOM   2379 O O     . TYR A 1 267 ? 17.18202  -16.43503 4.11013   1.000 10.48736  ? 1273 TYR A O     1 
ATOM   2380 C CB    . TYR A 1 267 ? 19.37937  -18.29016 5.20926   1.000 9.70267   ? 1273 TYR A CB    1 
ATOM   2381 C CG    . TYR A 1 267 ? 20.82852  -18.69894 5.12968   1.000 9.36375   ? 1273 TYR A CG    1 
ATOM   2382 C CD1   . TYR A 1 267 ? 21.80537  -17.80921 4.68727   1.000 9.53871   ? 1273 TYR A CD1   1 
ATOM   2383 C CD2   . TYR A 1 267 ? 21.22508  -19.98555 5.48057   1.000 9.62939   ? 1273 TYR A CD2   1 
ATOM   2384 C CE1   . TYR A 1 267 ? 23.13144  -18.19095 4.59804   1.000 9.35856   ? 1273 TYR A CE1   1 
ATOM   2385 C CE2   . TYR A 1 267 ? 22.55983  -20.37010 5.39985   1.000 9.70485   ? 1273 TYR A CE2   1 
ATOM   2386 C CZ    . TYR A 1 267 ? 23.50319  -19.47550 4.94337   1.000 9.77193   ? 1273 TYR A CZ    1 
ATOM   2387 O OH    . TYR A 1 267 ? 24.80605  -19.86341 4.84810   1.000 10.10313  ? 1273 TYR A OH    1 
ATOM   2388 N N     . PHE A 1 268 ? 16.29730  -18.50140 4.33450   1.000 10.08076  ? 1274 PHE A N     1 
ATOM   2389 C CA    . PHE A 1 268 ? 14.95541  -18.03930 4.64885   1.000 10.78415  ? 1274 PHE A CA    1 
ATOM   2390 C C     . PHE A 1 268 ? 14.44218  -18.79463 5.85720   1.000 11.05188  ? 1274 PHE A C     1 
ATOM   2391 O O     . PHE A 1 268 ? 14.50516  -20.02809 5.89429   1.000 11.56651  ? 1274 PHE A O     1 
ATOM   2392 C CB    . PHE A 1 268 ? 14.01801  -18.28708 3.47170   1.000 11.45878  ? 1274 PHE A CB    1 
ATOM   2393 C CG    . PHE A 1 268 ? 14.46088  -17.61634 2.21162   1.000 11.23946  ? 1274 PHE A CG    1 
ATOM   2394 C CD1   . PHE A 1 268 ? 15.34965  -18.24589 1.35820   1.000 11.53101  ? 1274 PHE A CD1   1 
ATOM   2395 C CD2   . PHE A 1 268 ? 14.00723  -16.34204 1.89126   1.000 11.74341  ? 1274 PHE A CD2   1 
ATOM   2396 C CE1   . PHE A 1 268 ? 15.76948  -17.62140 0.20428   1.000 12.05898  ? 1274 PHE A CE1   1 
ATOM   2397 C CE2   . PHE A 1 268 ? 14.43125  -15.71513 0.74032   1.000 11.60320  ? 1274 PHE A CE2   1 
ATOM   2398 C CZ    . PHE A 1 268 ? 15.31378  -16.35668 -0.10704  1.000 12.01233  ? 1274 PHE A CZ    1 
ATOM   2399 N N     . CYS A 1 269 ? 13.90819  -18.05816 6.82782   1.000 10.60190  ? 1275 CYS A N     1 
ATOM   2400 C CA    . CYS A 1 269 ? 13.40392  -18.69230 8.03364   1.000 10.63279  ? 1275 CYS A CA    1 
ATOM   2401 C C     . CYS A 1 269 ? 12.26811  -17.86174 8.60807   1.000 11.16742  ? 1275 CYS A C     1 
ATOM   2402 O O     . CYS A 1 269 ? 12.31950  -16.62764 8.59377   1.000 11.26839  ? 1275 CYS A O     1 
ATOM   2403 C CB    . CYS A 1 269 ? 14.53265  -18.85387 9.05292   1.000 10.87247  ? 1275 CYS A CB    1 
ATOM   2404 S SG    . CYS A 1 269 ? 14.14762  -19.94456 10.43848  1.000 11.43118  ? 1275 CYS A SG    1 
ATOM   2405 N N     . GLY A 1 270 ? 11.26540  -18.54949 9.14171   1.000 11.99216  ? 1276 GLY A N     1 
ATOM   2406 C CA    . GLY A 1 270 ? 10.08503  -17.93187 9.70432   1.000 13.26699  ? 1276 GLY A CA    1 
ATOM   2407 C C     . GLY A 1 270 ? 8.84182   -18.68136 9.26777   1.000 13.51141  ? 1276 GLY A C     1 
ATOM   2408 O O     . GLY A 1 270 ? 8.91616   -19.82507 8.83381   1.000 13.76655  ? 1276 GLY A O     1 
ATOM   2409 N N     . LEU A 1 271 ? 7.68969   -18.02940 9.37869   1.000 14.98612  ? 1277 LEU A N     1 
ATOM   2410 C CA    . LEU A 1 271 ? 6.44157   -18.66356 8.97481   1.000 17.00409  ? 1277 LEU A CA    1 
ATOM   2411 C C     . LEU A 1 271 ? 6.42659   -18.90912 7.46910   1.000 17.50265  ? 1277 LEU A C     1 
ATOM   2412 O O     . LEU A 1 271 ? 6.87092   -18.07096 6.68299   1.000 17.57315  ? 1277 LEU A O     1 
ATOM   2413 C CB    . LEU A 1 271 ? 5.25987   -17.77861 9.36468   1.000 18.84915  ? 1277 LEU A CB    1 
ATOM   2414 C CG    . LEU A 1 271 ? 4.97506   -17.69195 10.86856  1.000 19.67607  ? 1277 LEU A CG    1 
ATOM   2415 C CD1   . LEU A 1 271 ? 3.69740   -16.91970 11.08615  1.000 22.22694  ? 1277 LEU A CD1   1 
ATOM   2416 C CD2   . LEU A 1 271 ? 4.85423   -19.07139 11.50182  1.000 19.48064  ? 1277 LEU A CD2   1 
ATOM   2417 N N     . LYS A 1 272 ? 5.89384   -20.06660 7.07311   1.000 17.82197  ? 1278 LYS A N     1 
ATOM   2418 C CA    . LYS A 1 272 ? 5.92251   -20.47062 5.67245   1.000 20.20547  ? 1278 LYS A CA    1 
ATOM   2419 C C     . LYS A 1 272 ? 5.18795   -19.48873 4.76999   1.000 19.56942  ? 1278 LYS A C     1 
ATOM   2420 O O     . LYS A 1 272 ? 5.50946   -19.39820 3.57756   1.000 20.28685  ? 1278 LYS A O     1 
ATOM   2421 C CB    . LYS A 1 272 ? 5.38607   -21.89779 5.55192   1.000 23.63786  ? 1278 LYS A CB    1 
ATOM   2422 C CG    . LYS A 1 272 ? 3.92950   -22.04657 5.94432   1.000 28.04540  ? 1278 LYS A CG    1 
ATOM   2423 C CD    . LYS A 1 272 ? 3.43407   -23.45725 5.68011   1.000 32.75542  ? 1278 LYS A CD    1 
ATOM   2424 C CE    . LYS A 1 272 ? 4.32839   -24.47035 6.39478   1.000 36.45591  ? 1278 LYS A CE    1 
ATOM   2425 N NZ    . LYS A 1 272 ? 3.80819   -25.86765 6.32290   1.000 38.91010  ? 1278 LYS A NZ    1 
ATOM   2426 N N     . GLY A 1 273 ? 4.24963   -18.71742 5.31930   1.000 19.60684  ? 1279 GLY A N     1 
ATOM   2427 C CA    . GLY A 1 273 ? 3.56626   -17.70498 4.53868   1.000 19.91774  ? 1279 GLY A CA    1 
ATOM   2428 C C     . GLY A 1 273 ? 4.45929   -16.58339 4.04928   1.000 20.06483  ? 1279 GLY A C     1 
ATOM   2429 O O     . GLY A 1 273 ? 4.00617   -15.79815 3.20593   1.000 20.61836  ? 1279 GLY A O     1 
ATOM   2430 N N     . MET A 1 274 ? 5.70721   -16.47765 4.54059   1.000 19.19689  ? 1280 MET A N     1 
ATOM   2431 C CA    . MET A 1 274 ? 6.59125   -15.43898 4.01003   1.000 18.55586  ? 1280 MET A CA    1 
ATOM   2432 C C     . MET A 1 274 ? 7.03427   -15.75214 2.58106   1.000 18.78003  ? 1280 MET A C     1 
ATOM   2433 O O     . MET A 1 274 ? 7.43886   -14.83608 1.85918   1.000 18.70633  ? 1280 MET A O     1 
ATOM   2434 C CB    . MET A 1 274 ? 7.91344   -15.27194 4.79404   1.000 17.83286  ? 1280 MET A CB    1 
ATOM   2435 C CG    . MET A 1 274 ? 8.78181   -16.51789 4.89581   1.000 16.44146  ? 1280 MET A CG    1 
ATOM   2436 S SD    . MET A 1 274 ? 10.08703  -16.42006 6.12096   1.000 14.77705  ? 1280 MET A SD    1 
ATOM   2437 C CE    . MET A 1 274 ? 11.27927  -15.38122 5.29837   1.000 14.37958  ? 1280 MET A CE    1 
ATOM   2438 N N     . MET A 1 275 ? 7.04145   -17.02317 2.18393   1.000 18.54482  ? 1281 MET A N     1 
ATOM   2439 C CA    . MET A 1 275 ? 7.68025   -17.44742 0.93528   1.000 17.67185  ? 1281 MET A CA    1 
ATOM   2440 C C     . MET A 1 275 ? 6.97217   -17.04850 -0.35379  1.000 18.41771  ? 1281 MET A C     1 
ATOM   2441 O O     . MET A 1 275 ? 7.65838   -16.65738 -1.30710  1.000 18.74069  ? 1281 MET A O     1 
ATOM   2442 C CB    . MET A 1 275 ? 8.06735   -18.93177 0.93512   1.000 17.10035  ? 1281 MET A CB    1 
ATOM   2443 C CG    . MET A 1 275 ? 9.13278   -19.38311 1.95198   1.000 16.79835  ? 1281 MET A CG    1 
ATOM   2444 S SD    . MET A 1 275 ? 10.60345  -18.31444 1.96303   1.000 15.14288  ? 1281 MET A SD    1 
ATOM   2445 C CE    . MET A 1 275 ? 11.29682  -18.82570 0.40893   1.000 15.55692  ? 1281 MET A CE    1 
ATOM   2446 N N     . PRO A 1 276 ? 5.63726   -17.15334 -0.46604  1.000 19.42181  ? 1282 PRO A N     1 
ATOM   2447 C CA    . PRO A 1 276 ? 5.01330   -16.78412 -1.75643  1.000 20.46895  ? 1282 PRO A CA    1 
ATOM   2448 C C     . PRO A 1 276 ? 5.32857   -15.36659 -2.20351  1.000 20.86193  ? 1282 PRO A C     1 
ATOM   2449 O O     . PRO A 1 276 ? 5.64205   -15.14404 -3.38300  1.000 21.31983  ? 1282 PRO A O     1 
ATOM   2450 C CB    . PRO A 1 276 ? 3.51523   -17.00945 -1.50631  1.000 20.84314  ? 1282 PRO A CB    1 
ATOM   2451 C CG    . PRO A 1 276 ? 3.49132   -18.07771 -0.46172  1.000 20.99927  ? 1282 PRO A CG    1 
ATOM   2452 C CD    . PRO A 1 276 ? 4.64185   -17.73283 0.46026   1.000 19.84495  ? 1282 PRO A CD    1 
ATOM   2453 N N     . GLY A 1 277 ? 5.25938   -14.39678 -1.29280  1.000 21.23155  ? 1283 GLY A N     1 
ATOM   2454 C CA    . GLY A 1 277 ? 5.58285   -13.02889 -1.65829  1.000 21.06859  ? 1283 GLY A CA    1 
ATOM   2455 C C     . GLY A 1 277 ? 7.03570   -12.86192 -2.05629  1.000 20.41947  ? 1283 GLY A C     1 
ATOM   2456 O O     . GLY A 1 277 ? 7.35760   -12.09795 -2.97381  1.000 21.39602  ? 1283 GLY A O     1 
ATOM   2457 N N     . ILE A 1 278 ? 7.93359   -13.57410 -1.37291  1.000 20.02558  ? 1284 ILE A N     1 
ATOM   2458 C CA    . ILE A 1 278 ? 9.34751   -13.52981 -1.72378  1.000 18.93726  ? 1284 ILE A CA    1 
ATOM   2459 C C     . ILE A 1 278 ? 9.56807   -14.08817 -3.12524  1.000 19.04856  ? 1284 ILE A C     1 
ATOM   2460 O O     . ILE A 1 278 ? 10.26932  -13.48656 -3.94820  1.000 19.03614  ? 1284 ILE A O     1 
ATOM   2461 C CB    . ILE A 1 278 ? 10.17691  -14.26092 -0.65435  1.000 18.35463  ? 1284 ILE A CB    1 
ATOM   2462 C CG1   . ILE A 1 278 ? 10.24710  -13.40705 0.61772   1.000 18.74793  ? 1284 ILE A CG1   1 
ATOM   2463 C CG2   . ILE A 1 278 ? 11.56157  -14.58784 -1.18440  1.000 17.91603  ? 1284 ILE A CG2   1 
ATOM   2464 C CD1   . ILE A 1 278 ? 10.71145  -14.14991 1.84388   1.000 18.67757  ? 1284 ILE A CD1   1 
ATOM   2465 N N     . GLN A 1 279 ? 8.97421   -15.24693 -3.41886  1.000 19.36505  ? 1285 GLN A N     1 
ATOM   2466 C CA    . GLN A 1 279 ? 9.10686   -15.80793 -4.76029  1.000 18.82141  ? 1285 GLN A CA    1 
ATOM   2467 C C     . GLN A 1 279 ? 8.55757   -14.85285 -5.81056  1.000 18.59941  ? 1285 GLN A C     1 
ATOM   2468 O O     . GLN A 1 279 ? 9.16054   -14.67978 -6.87466  1.000 18.44033  ? 1285 GLN A O     1 
ATOM   2469 C CB    . GLN A 1 279 ? 8.40956   -17.16562 -4.85523  1.000 18.72922  ? 1285 GLN A CB    1 
ATOM   2470 C CG    . GLN A 1 279 ? 9.01809   -18.25372 -3.98284  1.000 18.27334  ? 1285 GLN A CG    1 
ATOM   2471 C CD    . GLN A 1 279 ? 10.35038  -18.77414 -4.50871  1.000 17.64930  ? 1285 GLN A CD    1 
ATOM   2472 O OE1   . GLN A 1 279 ? 10.79754  -18.41003 -5.59812  1.000 19.00191  ? 1285 GLN A OE1   1 
ATOM   2473 N NE2   . GLN A 1 279 ? 10.99102  -19.63008 -3.72913  1.000 18.06761  ? 1285 GLN A NE2   1 
ATOM   2474 N N     . ASP A 1 280 ? 7.42334   -14.21021 -5.51978  1.000 19.57799  ? 1286 ASP A N     1 
ATOM   2475 C CA    A ASP A 1 280 ? 6.83807   -13.26685 -6.46616  0.711 20.24582  ? 1286 ASP A CA    1 
ATOM   2476 C CA    B ASP A 1 280 ? 6.83467   -13.26249 -6.46351  0.289 19.69347  ? 1286 ASP A CA    1 
ATOM   2477 C C     . ASP A 1 280 ? 7.78069   -12.09988 -6.73087  1.000 20.28263  ? 1286 ASP A C     1 
ATOM   2478 O O     . ASP A 1 280 ? 7.98582   -11.69989 -7.88498  1.000 20.95826  ? 1286 ASP A O     1 
ATOM   2479 C CB    A ASP A 1 280 ? 5.49820   -12.77309 -5.92438  0.711 21.63400  ? 1286 ASP A CB    1 
ATOM   2480 C CB    B ASP A 1 280 ? 5.50175   -12.73716 -5.92424  0.289 20.11263  ? 1286 ASP A CB    1 
ATOM   2481 C CG    A ASP A 1 280 ? 4.80533   -11.82070 -6.86730  0.711 23.57105  ? 1286 ASP A CG    1 
ATOM   2482 C CG    B ASP A 1 280 ? 4.42057   -13.80060 -5.87998  0.289 20.71454  ? 1286 ASP A CG    1 
ATOM   2483 O OD1   A ASP A 1 280 ? 4.31785   -12.27883 -7.92134  0.711 25.05599  ? 1286 ASP A OD1   1 
ATOM   2484 O OD1   B ASP A 1 280 ? 4.59582   -14.86364 -6.50875  0.289 21.12052  ? 1286 ASP A OD1   1 
ATOM   2485 O OD2   A ASP A 1 280 ? 4.74269   -10.61601 -6.54548  0.711 24.49834  ? 1286 ASP A OD2   1 
ATOM   2486 O OD2   B ASP A 1 280 ? 3.38614   -13.56510 -5.21938  0.289 21.59782  ? 1286 ASP A OD2   1 
ATOM   2487 N N     . THR A 1 281 ? 8.35939   -11.53479 -5.66986  1.000 20.49815  ? 1287 THR A N     1 
ATOM   2488 C CA    . THR A 1 281 ? 9.28113   -10.41705 -5.83545  1.000 20.12885  ? 1287 THR A CA    1 
ATOM   2489 C C     . THR A 1 281 ? 10.52042  -10.83963 -6.61506  1.000 18.58492  ? 1287 THR A C     1 
ATOM   2490 O O     . THR A 1 281 ? 10.96311  -10.13435 -7.52840  1.000 18.89848  ? 1287 THR A O     1 
ATOM   2491 C CB    . THR A 1 281 ? 9.66558   -9.85521  -4.46621  1.000 21.28578  ? 1287 THR A CB    1 
ATOM   2492 O OG1   . THR A 1 281 ? 8.54986   -9.15272  -3.90850  1.000 22.84670  ? 1287 THR A OG1   1 
ATOM   2493 C CG2   . THR A 1 281 ? 10.83732  -8.90142  -4.59396  1.000 21.30133  ? 1287 THR A CG2   1 
ATOM   2494 N N     . LEU A 1 282 ? 11.09269  -11.99637 -6.27636  1.000 17.14573  ? 1288 LEU A N     1 
ATOM   2495 C CA    . LEU A 1 282 ? 12.29660  -12.43865 -6.97267  1.000 16.38071  ? 1288 LEU A CA    1 
ATOM   2496 C C     . LEU A 1 282 ? 12.02099  -12.70831 -8.44688  1.000 16.49366  ? 1288 LEU A C     1 
ATOM   2497 O O     . LEU A 1 282 ? 12.86579  -12.42645 -9.30347  1.000 16.64359  ? 1288 LEU A O     1 
ATOM   2498 C CB    . LEU A 1 282 ? 12.89888  -13.65848 -6.27637  1.000 15.26071  ? 1288 LEU A CB    1 
ATOM   2499 C CG    . LEU A 1 282 ? 13.42946  -13.35968 -4.87338  1.000 15.44779  ? 1288 LEU A CG    1 
ATOM   2500 C CD1   . LEU A 1 282 ? 13.74375  -14.64404 -4.11977  1.000 15.79033  ? 1288 LEU A CD1   1 
ATOM   2501 C CD2   . LEU A 1 282 ? 14.65469  -12.45638 -4.94570  1.000 16.84953  ? 1288 LEU A CD2   1 
ATOM   2502 N N     . LYS A 1 283 ? 10.83904  -13.23762 -8.76294  1.000 17.36277  ? 1289 LYS A N     1 
ATOM   2503 C CA    . LYS A 1 283 ? 10.47310  -13.43797 -10.16021 1.000 18.68459  ? 1289 LYS A CA    1 
ATOM   2504 C C     . LYS A 1 283 ? 10.39744  -12.10743 -10.89828 1.000 18.27257  ? 1289 LYS A C     1 
ATOM   2505 O O     . LYS A 1 283 ? 10.89236  -11.98323 -12.02628 1.000 17.83539  ? 1289 LYS A O     1 
ATOM   2506 C CB    . LYS A 1 283 ? 9.13660   -14.17592 -10.23176 1.000 21.67275  ? 1289 LYS A CB    1 
ATOM   2507 C CG    . LYS A 1 283 ? 8.63700   -14.45627 -11.63551 1.000 26.75331  ? 1289 LYS A CG    1 
ATOM   2508 C CD    . LYS A 1 283 ? 7.18448   -14.91659 -11.61124 1.000 31.00626  ? 1289 LYS A CD    1 
ATOM   2509 C CE    . LYS A 1 283 ? 6.53398   -14.77463 -12.97711 1.000 34.44730  ? 1289 LYS A CE    1 
ATOM   2510 N NZ    . LYS A 1 283 ? 5.39861   -13.80990 -12.96918 1.000 36.59608  ? 1289 LYS A NZ    1 
ATOM   2511 N N     . LYS A 1 284 ? 9.79531   -11.09424 -10.26940 1.000 18.34627  ? 1290 LYS A N     1 
ATOM   2512 C CA    . LYS A 1 284 ? 9.65725   -9.79166  -10.91417 1.000 19.45092  ? 1290 LYS A CA    1 
ATOM   2513 C C     . LYS A 1 284 ? 11.00039  -9.08940  -11.05135 1.000 18.67511  ? 1290 LYS A C     1 
ATOM   2514 O O     . LYS A 1 284 ? 11.26198  -8.43195  -12.06832 1.000 19.86812  ? 1290 LYS A O     1 
ATOM   2515 C CB    . LYS A 1 284 ? 8.65665   -8.93105  -10.14369 1.000 20.14605  ? 1290 LYS A CB    1 
ATOM   2516 C CG    . LYS A 1 284 ? 7.22174   -9.38972  -10.34098 1.000 43.41827  ? 1290 LYS A CG    1 
ATOM   2517 C CD    . LYS A 1 284 ? 6.25393   -8.75058  -9.36312  1.000 77.26992  ? 1290 LYS A CD    1 
ATOM   2518 C CE    . LYS A 1 284 ? 4.90294   -9.44753  -9.43896  1.000 48.95632  ? 1290 LYS A CE    1 
ATOM   2519 N NZ    . LYS A 1 284 ? 3.94045   -8.96108  -8.41272  1.000 49.80192  ? 1290 LYS A NZ    1 
ATOM   2520 N N     . VAL A 1 285 ? 11.85671  -9.20253  -10.03611 1.000 17.66834  ? 1291 VAL A N     1 
ATOM   2521 C CA    . VAL A 1 285 ? 13.19447  -8.62886  -10.12717 1.000 17.60037  ? 1291 VAL A CA    1 
ATOM   2522 C C     . VAL A 1 285 ? 13.96587  -9.26974  -11.26969 1.000 16.07984  ? 1291 VAL A C     1 
ATOM   2523 O O     . VAL A 1 285 ? 14.59802  -8.58028  -12.07918 1.000 16.16559  ? 1291 VAL A O     1 
ATOM   2524 C CB    . VAL A 1 285 ? 13.93932  -8.78176  -8.79098  1.000 19.47547  ? 1291 VAL A CB    1 
ATOM   2525 C CG1   . VAL A 1 285 ? 15.42229  -8.50395  -8.99228  1.000 20.65220  ? 1291 VAL A CG1   1 
ATOM   2526 C CG2   . VAL A 1 285 ? 13.34040  -7.86259  -7.73364  1.000 21.24223  ? 1291 VAL A CG2   1 
ATOM   2527 N N     . ALA A 1 286 ? 13.92043  -10.60135 -11.35548 1.000 14.84794  ? 1292 ALA A N     1 
ATOM   2528 C CA    . ALA A 1 286 ? 14.60212  -11.29345 -12.44318 1.000 14.75364  ? 1292 ALA A CA    1 
ATOM   2529 C C     . ALA A 1 286 ? 14.07493  -10.82868 -13.79380 1.000 14.69771  ? 1292 ALA A C     1 
ATOM   2530 O O     . ALA A 1 286 ? 14.85041  -10.53922 -14.71037 1.000 14.66748  ? 1292 ALA A O     1 
ATOM   2531 C CB    . ALA A 1 286 ? 14.43831  -12.80459 -12.29050 1.000 14.42919  ? 1292 ALA A CB    1 
ATOM   2532 N N     . GLU A 1 287 ? 12.74984  -10.73610 -13.92459 1.000 15.93042  ? 1293 GLU A N     1 
ATOM   2533 C CA    A GLU A 1 287 ? 12.15224  -10.31535 -15.18803 0.419 16.98916  ? 1293 GLU A CA    1 
ATOM   2534 C CA    B GLU A 1 287 ? 12.15324  -10.31737 -15.18833 0.581 16.86654  ? 1293 GLU A CA    1 
ATOM   2535 C C     . GLU A 1 287 ? 12.63510  -8.93132  -15.59686 1.000 16.81679  ? 1293 GLU A C     1 
ATOM   2536 O O     . GLU A 1 287 ? 12.94472  -8.69621  -16.77236 1.000 16.53113  ? 1293 GLU A O     1 
ATOM   2537 C CB    A GLU A 1 287 ? 10.62781  -10.33654 -15.08019 0.419 19.29467  ? 1293 GLU A CB    1 
ATOM   2538 C CB    B GLU A 1 287 ? 10.62978  -10.35192 -15.07133 0.581 19.51341  ? 1293 GLU A CB    1 
ATOM   2539 C CG    A GLU A 1 287 ? 10.01685  -11.72302 -15.11618 0.419 22.30082  ? 1293 GLU A CG    1 
ATOM   2540 C CG    B GLU A 1 287 ? 9.89356   -10.38105 -16.39608 0.581 23.88116  ? 1293 GLU A CG    1 
ATOM   2541 C CD    A GLU A 1 287 ? 8.55936   -11.73550 -14.69006 0.419 24.58445  ? 1293 GLU A CD    1 
ATOM   2542 C CD    B GLU A 1 287 ? 9.67724   -8.99911  -16.98007 0.581 28.04593  ? 1293 GLU A CD    1 
ATOM   2543 O OE1   A GLU A 1 287 ? 8.09475   -10.73865 -14.09524 0.419 25.39786  ? 1293 GLU A OE1   1 
ATOM   2544 O OE1   B GLU A 1 287 ? 9.71211   -8.01238  -16.21574 0.581 29.19175  ? 1293 GLU A OE1   1 
ATOM   2545 O OE2   A GLU A 1 287 ? 7.87368   -12.74195 -14.96516 0.419 25.41325  ? 1293 GLU A OE2   1 
ATOM   2546 O OE2   B GLU A 1 287 ? 9.46726   -8.89882  -18.20542 0.581 29.80015  ? 1293 GLU A OE2   1 
ATOM   2547 N N     . ARG A 1 288 ? 12.70280  -7.99707  -14.64236 1.000 17.00782  ? 1294 ARG A N     1 
ATOM   2548 C CA    . ARG A 1 288 ? 13.16572  -6.65399  -14.97569 1.000 17.49083  ? 1294 ARG A CA    1 
ATOM   2549 C C     . ARG A 1 288 ? 14.60826  -6.66201  -15.44671 1.000 16.35060  ? 1294 ARG A C     1 
ATOM   2550 O O     . ARG A 1 288 ? 14.99905  -5.80988  -16.25246 1.000 17.82188  ? 1294 ARG A O     1 
ATOM   2551 C CB    . ARG A 1 288 ? 13.03145  -5.71478  -13.78007 1.000 21.25636  ? 1294 ARG A CB    1 
ATOM   2552 C CG    . ARG A 1 288 ? 11.61580  -5.43506  -13.34911 1.000 26.59501  ? 1294 ARG A CG    1 
ATOM   2553 C CD    . ARG A 1 288 ? 11.61748  -4.76638  -11.99402 1.000 31.71671  ? 1294 ARG A CD    1 
ATOM   2554 N NE    . ARG A 1 288 ? 10.28428  -4.72094  -11.41403 1.000 36.08774  ? 1294 ARG A NE    1 
ATOM   2555 C CZ    . ARG A 1 288 ? 10.04235  -4.77327  -10.11299 1.000 39.26064  ? 1294 ARG A CZ    1 
ATOM   2556 N NH1   . ARG A 1 288 ? 11.02489  -4.86664  -9.23143  1.000 39.98063  ? 1294 ARG A NH1   1 
ATOM   2557 N NH2   . ARG A 1 288 ? 8.78432   -4.73054  -9.68505  1.000 40.90838  ? 1294 ARG A NH2   1 
ATOM   2558 N N     . ARG A 1 289 ? 15.41354  -7.59452  -14.94398 1.000 16.38765  ? 1295 ARG A N     1 
ATOM   2559 C CA    . ARG A 1 289 ? 16.80037  -7.73663  -15.36122 1.000 16.82293  ? 1295 ARG A CA    1 
ATOM   2560 C C     . ARG A 1 289 ? 16.93774  -8.54998  -16.63808 1.000 16.44861  ? 1295 ARG A C     1 
ATOM   2561 O O     . ARG A 1 289 ? 18.05374  -8.69664  -17.14622 1.000 17.38730  ? 1295 ARG A O     1 
ATOM   2562 C CB    . ARG A 1 289 ? 17.60951  -8.41280  -14.25069 1.000 16.93988  ? 1295 ARG A CB    1 
ATOM   2563 C CG    . ARG A 1 289 ? 17.62495  -7.65371  -12.93192 1.000 17.88207  ? 1295 ARG A CG    1 
ATOM   2564 C CD    . ARG A 1 289 ? 18.19453  -8.50165  -11.79919 1.000 18.34901  ? 1295 ARG A CD    1 
ATOM   2565 N NE    . ARG A 1 289 ? 19.57722  -8.90731  -12.03569 1.000 18.21604  ? 1295 ARG A NE    1 
ATOM   2566 C CZ    . ARG A 1 289 ? 20.63040  -8.14223  -11.78041 1.000 18.67076  ? 1295 ARG A CZ    1 
ATOM   2567 N NH1   . ARG A 1 289 ? 20.49427  -6.91718  -11.29803 1.000 18.80974  ? 1295 ARG A NH1   1 
ATOM   2568 N NH2   . ARG A 1 289 ? 21.85060  -8.61622  -12.01283 1.000 19.54061  ? 1295 ARG A NH2   1 
ATOM   2569 N N     . GLY A 1 290 ? 15.83989  -9.08522  -17.16330 1.000 15.87300  ? 1296 GLY A N     1 
ATOM   2570 C CA    . GLY A 1 290 ? 15.91749  -9.94117  -18.32899 1.000 16.12839  ? 1296 GLY A CA    1 
ATOM   2571 C C     . GLY A 1 290 ? 16.36399  -11.35416 -18.04058 1.000 15.94393  ? 1296 GLY A C     1 
ATOM   2572 O O     . GLY A 1 290 ? 16.87312  -12.03209 -18.94238 1.000 17.34131  ? 1296 GLY A O     1 
ATOM   2573 N N     . GLU A 1 291 ? 16.18517  -11.81230 -16.80346 1.000 15.71001  ? 1297 GLU A N     1 
ATOM   2574 C CA    A GLU A 1 291 ? 16.57530  -13.13104 -16.32382 0.524 16.53239  ? 1297 GLU A CA    1 
ATOM   2575 C CA    B GLU A 1 291 ? 16.57028  -13.14937 -16.38955 0.476 15.85903  ? 1297 GLU A CA    1 
ATOM   2576 C C     . GLU A 1 291 ? 15.33218  -13.96306 -16.03862 1.000 15.54329  ? 1297 GLU A C     1 
ATOM   2577 O O     . GLU A 1 291 ? 14.26022  -13.42721 -15.75002 1.000 17.79341  ? 1297 GLU A O     1 
ATOM   2578 C CB    A GLU A 1 291 ? 17.32556  -13.01283 -14.99281 0.524 17.51109  ? 1297 GLU A CB    1 
ATOM   2579 C CB    B GLU A 1 291 ? 17.53655  -13.09753 -15.19583 0.476 15.33546  ? 1297 GLU A CB    1 
ATOM   2580 C CG    A GLU A 1 291 ? 18.75471  -12.52926 -15.05809 0.524 18.83628  ? 1297 GLU A CG    1 
ATOM   2581 C CG    B GLU A 1 291 ? 18.69688  -12.13342 -15.41145 0.476 15.70510  ? 1297 GLU A CG    1 
ATOM   2582 C CD    A GLU A 1 291 ? 19.37684  -12.48356 -13.67045 0.524 19.81457  ? 1297 GLU A CD    1 
ATOM   2583 C CD    B GLU A 1 291 ? 19.74253  -12.18489 -14.31243 0.476 17.55339  ? 1297 GLU A CD    1 
ATOM   2584 O OE1   A GLU A 1 291 ? 19.81118  -13.54386 -13.17563 0.524 21.56819  ? 1297 GLU A OE1   1 
ATOM   2585 O OE1   B GLU A 1 291 ? 20.29062  -13.27628 -14.05468 0.476 17.54172  ? 1297 GLU A OE1   1 
ATOM   2586 O OE2   A GLU A 1 291 ? 19.40992  -11.40099 -13.05490 0.524 18.46893  ? 1297 GLU A OE2   1 
ATOM   2587 O OE2   B GLU A 1 291 ? 20.04477  -11.12168 -13.73205 0.476 19.83244  ? 1297 GLU A OE2   1 
ATOM   2588 N N     . SER A 1 292 ? 15.49520  -15.28102 -16.07357 1.000 16.00133  ? 1298 SER A N     1 
ATOM   2589 C CA    . SER A 1 292 ? 14.45138  -16.21390 -15.66576 1.000 15.60670  ? 1298 SER A CA    1 
ATOM   2590 C C     . SER A 1 292 ? 14.69675  -16.59929 -14.21352 1.000 14.24402  ? 1298 SER A C     1 
ATOM   2591 O O     . SER A 1 292 ? 15.72740  -17.20416 -13.89723 1.000 14.34827  ? 1298 SER A O     1 
ATOM   2592 C CB    . SER A 1 292 ? 14.49745  -17.46984 -16.53210 1.000 17.33787  ? 1298 SER A CB    1 
ATOM   2593 O OG    . SER A 1 292 ? 13.85206  -18.55529 -15.88893 1.000 17.80431  ? 1298 SER A OG    1 
ATOM   2594 N N     . TRP A 1 293 ? 13.75509  -16.25967 -13.33214 1.000 14.86502  ? 1299 TRP A N     1 
ATOM   2595 C CA    . TRP A 1 293 ? 13.92459  -16.65201 -11.93949 1.000 14.45430  ? 1299 TRP A CA    1 
ATOM   2596 C C     . TRP A 1 293 ? 13.90656  -18.16968 -11.78542 1.000 14.27462  ? 1299 TRP A C     1 
ATOM   2597 O O     . TRP A 1 293 ? 14.64473  -18.72191 -10.96333 1.000 15.03723  ? 1299 TRP A O     1 
ATOM   2598 C CB    . TRP A 1 293 ? 12.87925  -15.99122 -11.04327 1.000 15.01839  ? 1299 TRP A CB    1 
ATOM   2599 C CG    . TRP A 1 293 ? 12.99350  -16.46879 -9.64016  1.000 15.44871  ? 1299 TRP A CG    1 
ATOM   2600 C CD1   . TRP A 1 293 ? 12.06712  -17.17803 -8.93764  1.000 16.43656  ? 1299 TRP A CD1   1 
ATOM   2601 C CD2   . TRP A 1 293 ? 14.12541  -16.31630 -8.77455  1.000 15.76769  ? 1299 TRP A CD2   1 
ATOM   2602 N NE1   . TRP A 1 293 ? 12.54442  -17.46529 -7.68312  1.000 17.52530  ? 1299 TRP A NE1   1 
ATOM   2603 C CE2   . TRP A 1 293 ? 13.80514  -16.94584 -7.55814  1.000 16.60890  ? 1299 TRP A CE2   1 
ATOM   2604 C CE3   . TRP A 1 293 ? 15.37233  -15.69876 -8.90602  1.000 15.94081  ? 1299 TRP A CE3   1 
ATOM   2605 C CZ2   . TRP A 1 293 ? 14.68652  -16.98400 -6.48493  1.000 17.62158  ? 1299 TRP A CZ2   1 
ATOM   2606 C CZ3   . TRP A 1 293 ? 16.24672  -15.73259 -7.83215  1.000 16.68313  ? 1299 TRP A CZ3   1 
ATOM   2607 C CH2   . TRP A 1 293 ? 15.89856  -16.37183 -6.63853  1.000 18.07791  ? 1299 TRP A CH2   1 
ATOM   2608 N N     . ASP A 1 294 ? 13.09275  -18.86645 -12.58324 1.000 14.83970  ? 1300 ASP A N     1 
ATOM   2609 C CA    . ASP A 1 294 ? 13.08549  -20.32550 -12.51436 1.000 15.64754  ? 1300 ASP A CA    1 
ATOM   2610 C C     . ASP A 1 294 ? 14.48227  -20.88095 -12.74986 1.000 15.10828  ? 1300 ASP A C     1 
ATOM   2611 O O     . ASP A 1 294 ? 14.97209  -21.72487 -11.99250 1.000 14.73530  ? 1300 ASP A O     1 
ATOM   2612 C CB    . ASP A 1 294 ? 12.11905  -20.90373 -13.54913 1.000 17.20797  ? 1300 ASP A CB    1 
ATOM   2613 C CG    . ASP A 1 294 ? 10.66740  -20.68212 -13.18786 1.000 18.74680  ? 1300 ASP A CG    1 
ATOM   2614 O OD1   . ASP A 1 294 ? 10.35509  -20.58633 -11.98310 1.000 19.97635  ? 1300 ASP A OD1   1 
ATOM   2615 O OD2   . ASP A 1 294 ? 9.83832   -20.59263 -14.12336 1.000 20.77543  ? 1300 ASP A OD2   1 
ATOM   2616 N N     . GLN A 1 295 ? 15.14165  -20.41220 -13.80564 1.000 15.24432  ? 1301 GLN A N     1 
ATOM   2617 C CA    A GLN A 1 295 ? 16.47878  -20.90990 -14.08603 0.648 16.52085  ? 1301 GLN A CA    1 
ATOM   2618 C CA    B GLN A 1 295 ? 16.49243  -20.87507 -14.11147 0.352 16.28401  ? 1301 GLN A CA    1 
ATOM   2619 C C     . GLN A 1 295 ? 17.46705  -20.48442 -13.00968 1.000 14.89630  ? 1301 GLN A C     1 
ATOM   2620 O O     . GLN A 1 295 ? 18.34255  -21.27040 -12.63174 1.000 14.66705  ? 1301 GLN A O     1 
ATOM   2621 C CB    A GLN A 1 295 ? 16.91723  -20.49783 -15.48582 0.648 19.80221  ? 1301 GLN A CB    1 
ATOM   2622 C CB    B GLN A 1 295 ? 16.94580  -20.29211 -15.45057 0.352 19.00500  ? 1301 GLN A CB    1 
ATOM   2623 C CG    A GLN A 1 295 ? 16.18976  -21.28930 -16.56264 0.648 22.35517  ? 1301 GLN A CG    1 
ATOM   2624 C CG    B GLN A 1 295 ? 18.39355  -20.59088 -15.81365 0.352 21.44556  ? 1301 GLN A CG    1 
ATOM   2625 C CD    A GLN A 1 295 ? 16.19645  -20.59560 -17.89705 0.648 25.44420  ? 1301 GLN A CD    1 
ATOM   2626 C CD    B GLN A 1 295 ? 18.52309  -21.66121 -16.88386 0.352 24.09595  ? 1301 GLN A CD    1 
ATOM   2627 O OE1   A GLN A 1 295 ? 17.18861  -19.98205 -18.28062 0.648 27.19346  ? 1301 GLN A OE1   1 
ATOM   2628 O OE1   B GLN A 1 295 ? 17.91053  -22.72768 -16.79613 0.352 24.68146  ? 1301 GLN A OE1   1 
ATOM   2629 N NE2   A GLN A 1 295 ? 15.08470  -20.68390 -18.61675 0.648 26.04402  ? 1301 GLN A NE2   1 
ATOM   2630 N NE2   B GLN A 1 295 ? 19.32936  -21.38135 -17.90097 0.352 25.09928  ? 1301 GLN A NE2   1 
ATOM   2631 N N     . LYS A 1 296 ? 17.33355  -19.26366 -12.48629 1.000 13.87845  ? 1302 LYS A N     1 
ATOM   2632 C CA    A LYS A 1 296 ? 18.23579  -18.82947 -11.42870 0.531 13.72496  ? 1302 LYS A CA    1 
ATOM   2633 C CA    B LYS A 1 296 ? 18.22553  -18.81529 -11.41836 0.469 13.54411  ? 1302 LYS A CA    1 
ATOM   2634 C C     . LYS A 1 296 ? 18.05351  -19.67145 -10.17160 1.000 12.49428  ? 1302 LYS A C     1 
ATOM   2635 O O     . LYS A 1 296 ? 19.03455  -20.11138 -9.56014  1.000 13.00378  ? 1302 LYS A O     1 
ATOM   2636 C CB    A LYS A 1 296 ? 18.01849  -17.35037 -11.12995 0.531 14.59940  ? 1302 LYS A CB    1 
ATOM   2637 C CB    B LYS A 1 296 ? 17.95530  -17.34704 -11.07876 0.469 13.87013  ? 1302 LYS A CB    1 
ATOM   2638 C CG    A LYS A 1 296 ? 19.11984  -16.75256 -10.29605 0.531 15.57660  ? 1302 LYS A CG    1 
ATOM   2639 C CG    B LYS A 1 296 ? 18.44864  -16.33144 -12.09734 0.469 14.16128  ? 1302 LYS A CG    1 
ATOM   2640 C CD    A LYS A 1 296 ? 19.01883  -15.24327 -10.24586 0.531 16.68269  ? 1302 LYS A CD    1 
ATOM   2641 C CD    B LYS A 1 296 ? 18.63136  -14.95230 -11.46107 0.469 14.76059  ? 1302 LYS A CD    1 
ATOM   2642 C CE    A LYS A 1 296 ? 20.38260  -14.61128 -10.04603 0.531 17.15417  ? 1302 LYS A CE    1 
ATOM   2643 C CE    B LYS A 1 296 ? 19.99699  -14.80789 -10.81222 0.469 15.20493  ? 1302 LYS A CE    1 
ATOM   2644 N NZ    A LYS A 1 296 ? 21.19749  -14.66831 -11.29033 0.531 17.58178  ? 1302 LYS A NZ    1 
ATOM   2645 N NZ    B LYS A 1 296 ? 21.08744  -14.89978 -11.81824 0.469 14.71535  ? 1302 LYS A NZ    1 
ATOM   2646 N N     . LEU A 1 297 ? 16.80497  -19.90443 -9.77254  1.000 12.08028  ? 1303 LEU A N     1 
ATOM   2647 C CA    . LEU A 1 297 ? 16.56174  -20.70055 -8.57686  1.000 12.11785  ? 1303 LEU A CA    1 
ATOM   2648 C C     . LEU A 1 297 ? 17.04925  -22.13603 -8.75771  1.000 11.70956  ? 1303 LEU A C     1 
ATOM   2649 O O     . LEU A 1 297 ? 17.61139  -22.72703 -7.82930  1.000 12.11629  ? 1303 LEU A O     1 
ATOM   2650 C CB    . LEU A 1 297 ? 15.07745  -20.65723 -8.22077  1.000 12.33116  ? 1303 LEU A CB    1 
ATOM   2651 C CG    . LEU A 1 297 ? 14.68304  -21.45118 -6.97686  1.000 12.38306  ? 1303 LEU A CG    1 
ATOM   2652 C CD1   . LEU A 1 297 ? 15.50506  -21.02922 -5.75160  1.000 12.76162  ? 1303 LEU A CD1   1 
ATOM   2653 C CD2   . LEU A 1 297 ? 13.19059  -21.30363 -6.72616  1.000 13.77270  ? 1303 LEU A CD2   1 
ATOM   2654 N N     . ALA A 1 298 ? 16.84103  -22.71981 -9.94323  1.000 12.05646  ? 1304 ALA A N     1 
ATOM   2655 C CA    . ALA A 1 298 ? 17.37226  -24.05743 -10.19468 1.000 12.54072  ? 1304 ALA A CA    1 
ATOM   2656 C C     . ALA A 1 298 ? 18.88610  -24.08518 -10.01372 1.000 12.56157  ? 1304 ALA A C     1 
ATOM   2657 O O     . ALA A 1 298 ? 19.43492  -25.02262 -9.42074  1.000 12.96810  ? 1304 ALA A O     1 
ATOM   2658 C CB    . ALA A 1 298 ? 16.97538  -24.53352 -11.59265 1.000 12.85015  ? 1304 ALA A CB    1 
ATOM   2659 N N     . GLN A 1 299 ? 19.58024  -23.05661 -10.50388 1.000 12.69780  ? 1305 GLN A N     1 
ATOM   2660 C CA    A GLN A 1 299 ? 21.02657  -23.03824 -10.34369 0.582 13.60169  ? 1305 GLN A CA    1 
ATOM   2661 C CA    B GLN A 1 299 ? 21.03090  -22.98737 -10.35107 0.418 13.19588  ? 1305 GLN A CA    1 
ATOM   2662 C C     . GLN A 1 299 ? 21.42319  -22.82364 -8.88860  1.000 12.66120  ? 1305 GLN A C     1 
ATOM   2663 O O     . GLN A 1 299 ? 22.37145  -23.45922 -8.41186  1.000 12.81662  ? 1305 GLN A O     1 
ATOM   2664 C CB    A GLN A 1 299 ? 21.67075  -21.99772 -11.25457 0.582 15.40919  ? 1305 GLN A CB    1 
ATOM   2665 C CB    B GLN A 1 299 ? 21.57074  -21.81600 -11.17349 0.418 14.00640  ? 1305 GLN A CB    1 
ATOM   2666 C CG    A GLN A 1 299 ? 23.17875  -22.19849 -11.43256 0.582 17.91016  ? 1305 GLN A CG    1 
ATOM   2667 C CG    B GLN A 1 299 ? 23.06150  -21.54231 -11.00400 0.418 15.77238  ? 1305 GLN A CG    1 
ATOM   2668 C CD    A GLN A 1 299 ? 23.53782  -23.55164 -12.03946 0.582 20.52539  ? 1305 GLN A CD    1 
ATOM   2669 C CD    B GLN A 1 299 ? 23.55370  -20.40322 -11.88959 0.418 17.04667  ? 1305 GLN A CD    1 
ATOM   2670 O OE1   A GLN A 1 299 ? 22.94660  -23.97793 -13.02933 0.582 22.44042  ? 1305 GLN A OE1   1 
ATOM   2671 O OE1   B GLN A 1 299 ? 24.00996  -19.36612 -11.40186 0.418 18.44621  ? 1305 GLN A OE1   1 
ATOM   2672 N NE2   A GLN A 1 299 ? 24.52475  -24.22071 -11.45603 0.582 20.42139  ? 1305 GLN A NE2   1 
ATOM   2673 N NE2   B GLN A 1 299 ? 23.45226  -20.59082 -13.19809 0.418 17.29018  ? 1305 GLN A NE2   1 
ATOM   2674 N N     . LEU A 1 300 ? 20.72270  -21.93747 -8.16976  1.000 12.06084  ? 1306 LEU A N     1 
ATOM   2675 C CA    . LEU A 1 300 ? 21.03317  -21.73328 -6.75764  1.000 12.01474  ? 1306 LEU A CA    1 
ATOM   2676 C C     . LEU A 1 300 ? 20.86220  -23.02170 -5.96403  1.000 11.92876  ? 1306 LEU A C     1 
ATOM   2677 O O     . LEU A 1 300 ? 21.68342  -23.33756 -5.09139  1.000 12.96775  ? 1306 LEU A O     1 
ATOM   2678 C CB    . LEU A 1 300 ? 20.16679  -20.61928 -6.17285  1.000 12.46003  ? 1306 LEU A CB    1 
ATOM   2679 C CG    . LEU A 1 300 ? 20.43765  -19.21114 -6.71276  1.000 13.17967  ? 1306 LEU A CG    1 
ATOM   2680 C CD1   . LEU A 1 300 ? 19.34600  -18.24858 -6.26644  1.000 14.50757  ? 1306 LEU A CD1   1 
ATOM   2681 C CD2   . LEU A 1 300 ? 21.81127  -18.72619 -6.27533  1.000 13.98250  ? 1306 LEU A CD2   1 
ATOM   2682 N N     . LYS A 1 301 ? 19.80282  -23.78287 -6.25504  1.000 11.96306  ? 1307 LYS A N     1 
ATOM   2683 C CA    . LYS A 1 301 ? 19.62241  -25.06256 -5.57769  1.000 12.58352  ? 1307 LYS A CA    1 
ATOM   2684 C C     . LYS A 1 301 ? 20.69766  -26.06560 -5.96753  1.000 13.17218  ? 1307 LYS A C     1 
ATOM   2685 O O     . LYS A 1 301 ? 21.22093  -26.78850 -5.10735  1.000 13.97258  ? 1307 LYS A O     1 
ATOM   2686 C CB    . LYS A 1 301 ? 18.21257  -25.62318 -5.78558  1.000 12.75117  ? 1307 LYS A CB    1 
ATOM   2687 C CG    . LYS A 1 301 ? 17.10929  -24.76239 -5.17258  1.000 13.89667  ? 1307 LYS A CG    1 
ATOM   2688 C CD    . LYS A 1 301 ? 15.72910  -25.35381 -5.40532  1.000 15.08895  ? 1307 LYS A CD    1 
ATOM   2689 C CE    . LYS A 1 301 ? 14.66247  -24.63383 -4.59417  1.000 17.04184  ? 1307 LYS A CE    1 
ATOM   2690 N NZ    . LYS A 1 301 ? 13.43809  -25.45991 -4.37893  1.000 19.44171  ? 1307 LYS A NZ    1 
ATOM   2691 N N     . LYS A 1 302 ? 21.02259  -26.14361 -7.25916  1.000 13.64499  ? 1308 LYS A N     1 
ATOM   2692 C CA    . LYS A 1 302 ? 22.05944  -27.07000 -7.69632  1.000 14.51496  ? 1308 LYS A CA    1 
ATOM   2693 C C     . LYS A 1 302 ? 23.39042  -26.74621 -7.02904  1.000 13.97051  ? 1308 LYS A C     1 
ATOM   2694 O O     . LYS A 1 302 ? 24.14535  -27.65107 -6.65083  1.000 15.64090  ? 1308 LYS A O     1 
ATOM   2695 C CB    . LYS A 1 302 ? 22.17971  -27.01336 -9.21669  1.000 16.60644  ? 1308 LYS A CB    1 
ATOM   2696 C CG    . LYS A 1 302 ? 23.21998  -27.93638 -9.78774  1.000 20.92588  ? 1308 LYS A CG    1 
ATOM   2697 C CD    . LYS A 1 302 ? 23.13087  -27.95686 -11.30219 1.000 25.38180  ? 1308 LYS A CD    1 
ATOM   2698 C CE    . LYS A 1 302 ? 23.90702  -29.12106 -11.88890 1.000 29.26255  ? 1308 LYS A CE    1 
ATOM   2699 N NZ    . LYS A 1 302 ? 23.69519  -29.22635 -13.35821 1.000 31.62193  ? 1308 LYS A NZ    1 
ATOM   2700 N N     . ASN A 1 303 ? 23.68344  -25.45676 -6.86178  1.000 13.08809  ? 1309 ASN A N     1 
ATOM   2701 C CA    . ASN A 1 303 ? 24.92622  -24.98833 -6.26711  1.000 12.99265  ? 1309 ASN A CA    1 
ATOM   2702 C C     . ASN A 1 303 ? 24.89962  -25.01229 -4.74337  1.000 12.63250  ? 1309 ASN A C     1 
ATOM   2703 O O     . ASN A 1 303 ? 25.88743  -24.60492 -4.12031  1.000 14.11825  ? 1309 ASN A O     1 
ATOM   2704 C CB    . ASN A 1 303 ? 25.18238  -23.53390 -6.67345  1.000 15.07569  ? 1309 ASN A CB    1 
ATOM   2705 C CG    . ASN A 1 303 ? 25.56245  -23.37103 -8.12478  1.000 17.47821  ? 1309 ASN A CG    1 
ATOM   2706 O OD1   . ASN A 1 303 ? 25.79386  -24.34287 -8.84075  1.000 18.71157  ? 1309 ASN A OD1   1 
ATOM   2707 N ND2   . ASN A 1 303 ? 25.64310  -22.11826 -8.56760  1.000 18.20228  ? 1309 ASN A ND2   1 
ATOM   2708 N N     . LYS A 1 304 ? 23.79148  -25.43438 -4.13674  1.000 12.80819  ? 1310 LYS A N     1 
ATOM   2709 C CA    . LYS A 1 304 ? 23.66873  -25.51766 -2.67746  1.000 13.26635  ? 1310 LYS A CA    1 
ATOM   2710 C C     . LYS A 1 304 ? 23.78925  -24.15016 -2.00291  1.000 11.53110  ? 1310 LYS A C     1 
ATOM   2711 O O     . LYS A 1 304 ? 24.33481  -24.02131 -0.90088  1.000 11.98843  ? 1310 LYS A O     1 
ATOM   2712 C CB    . LYS A 1 304 ? 24.62434  -26.54754 -2.07196  1.000 15.81160  ? 1310 LYS A CB    1 
ATOM   2713 C CG    . LYS A 1 304 ? 24.40426  -27.95329 -2.60091  1.000 20.80556  ? 1310 LYS A CG    1 
ATOM   2714 C CD    . LYS A 1 304 ? 25.46703  -28.90806 -2.08347  1.000 25.91094  ? 1310 LYS A CD    1 
ATOM   2715 C CE    . LYS A 1 304 ? 25.22648  -30.32129 -2.59091  1.000 30.11557  ? 1310 LYS A CE    1 
ATOM   2716 N NZ    . LYS A 1 304 ? 23.81670  -30.75487 -2.35059  1.000 32.22220  ? 1310 LYS A NZ    1 
ATOM   2717 N N     . GLN A 1 305 ? 23.24161  -23.12785 -2.66145  1.000 10.63764  ? 1311 GLN A N     1 
ATOM   2718 C CA    . GLN A 1 305 ? 23.23357  -21.76898 -2.14424  1.000 10.46014  ? 1311 GLN A CA    1 
ATOM   2719 C C     . GLN A 1 305 ? 21.91920  -21.38434 -1.47223  1.000 10.08578  ? 1311 GLN A C     1 
ATOM   2720 O O     . GLN A 1 305 ? 21.83500  -20.29245 -0.90516  1.000 11.00014  ? 1311 GLN A O     1 
ATOM   2721 C CB    . GLN A 1 305 ? 23.48473  -20.76545 -3.27545  1.000 10.75972  ? 1311 GLN A CB    1 
ATOM   2722 C CG    . GLN A 1 305 ? 24.87333  -20.76166 -3.83380  1.000 11.02121  ? 1311 GLN A CG    1 
ATOM   2723 C CD    . GLN A 1 305 ? 24.95184  -19.91301 -5.09241  1.000 11.59788  ? 1311 GLN A CD    1 
ATOM   2724 O OE1   . GLN A 1 305 ? 24.92832  -20.43379 -6.20692  1.000 14.21516  ? 1311 GLN A OE1   1 
ATOM   2725 N NE2   . GLN A 1 305 ? 25.01949  -18.60083 -4.92459  1.000 11.07902  ? 1311 GLN A NE2   1 
ATOM   2726 N N     . TRP A 1 306 ? 20.88866  -22.22617 -1.54894  1.000 10.67328  ? 1312 TRP A N     1 
ATOM   2727 C CA    . TRP A 1 306 ? 19.52092  -21.84921 -1.20793  1.000 10.85115  ? 1312 TRP A CA    1 
ATOM   2728 C C     . TRP A 1 306 ? 19.06670  -22.66123 -0.00336  1.000 10.80507  ? 1312 TRP A C     1 
ATOM   2729 O O     . TRP A 1 306 ? 18.94581  -23.88609 -0.09232  1.000 12.12897  ? 1312 TRP A O     1 
ATOM   2730 C CB    . TRP A 1 306 ? 18.62770  -22.13893 -2.41556  1.000 11.73461  ? 1312 TRP A CB    1 
ATOM   2731 C CG    . TRP A 1 306 ? 17.19674  -21.74785 -2.26816  1.000 12.47226  ? 1312 TRP A CG    1 
ATOM   2732 C CD1   . TRP A 1 306 ? 16.16928  -22.54655 -1.86847  1.000 14.03935  ? 1312 TRP A CD1   1 
ATOM   2733 C CD2   . TRP A 1 306 ? 16.61924  -20.46945 -2.56521  1.000 13.29803  ? 1312 TRP A CD2   1 
ATOM   2734 N NE1   . TRP A 1 306 ? 14.99018  -21.84557 -1.89092  1.000 14.36685  ? 1312 TRP A NE1   1 
ATOM   2735 C CE2   . TRP A 1 306 ? 15.23846  -20.56753 -2.31221  1.000 14.62055  ? 1312 TRP A CE2   1 
ATOM   2736 C CE3   . TRP A 1 306 ? 17.13535  -19.25570 -3.03640  1.000 14.06385  ? 1312 TRP A CE3   1 
ATOM   2737 C CZ2   . TRP A 1 306 ? 14.36755  -19.49717 -2.49916  1.000 15.08006  ? 1312 TRP A CZ2   1 
ATOM   2738 C CZ3   . TRP A 1 306 ? 16.26762  -18.19278 -3.21958  1.000 16.04228  ? 1312 TRP A CZ3   1 
ATOM   2739 C CH2   . TRP A 1 306 ? 14.89837  -18.32440 -2.95841  1.000 16.53678  ? 1312 TRP A CH2   1 
ATOM   2740 N N     . HIS A 1 307 ? 18.77921  -21.98800 1.10945   1.000 10.67674  ? 1313 HIS A N     1 
ATOM   2741 C CA    . HIS A 1 307 ? 18.54370  -22.67674 2.37647   1.000 11.09890  ? 1313 HIS A CA    1 
ATOM   2742 C C     . HIS A 1 307 ? 17.25092  -22.16795 2.99499   1.000 11.45420  ? 1313 HIS A C     1 
ATOM   2743 O O     . HIS A 1 307 ? 17.17856  -21.00136 3.38316   1.000 12.97693  ? 1313 HIS A O     1 
ATOM   2744 C CB    . HIS A 1 307 ? 19.72573  -22.43670 3.32040   1.000 11.75001  ? 1313 HIS A CB    1 
ATOM   2745 C CG    . HIS A 1 307 ? 21.05042  -22.60869 2.65128   1.000 11.00880  ? 1313 HIS A CG    1 
ATOM   2746 N ND1   . HIS A 1 307 ? 21.55562  -23.84481 2.30723   1.000 11.79389  ? 1313 HIS A ND1   1 
ATOM   2747 C CD2   . HIS A 1 307 ? 21.95221  -21.69825 2.21356   1.000 11.00156  ? 1313 HIS A CD2   1 
ATOM   2748 C CE1   . HIS A 1 307 ? 22.72694  -23.68933 1.71314   1.000 11.59530  ? 1313 HIS A CE1   1 
ATOM   2749 N NE2   . HIS A 1 307 ? 22.99314  -22.39581 1.64754   1.000 10.87097  ? 1313 HIS A NE2   1 
ATOM   2750 N N     . VAL A 1 308 ? 16.24179  -23.02945 3.11113   1.000 11.65076  ? 1314 VAL A N     1 
ATOM   2751 C CA    . VAL A 1 308 ? 14.92030  -22.61049 3.57079   1.000 11.62794  ? 1314 VAL A CA    1 
ATOM   2752 C C     . VAL A 1 308 ? 14.48796  -23.49879 4.72305   1.000 11.33119  ? 1314 VAL A C     1 
ATOM   2753 O O     . VAL A 1 308 ? 14.47532  -24.72748 4.59124   1.000 12.59131  ? 1314 VAL A O     1 
ATOM   2754 C CB    . VAL A 1 308 ? 13.86326  -22.70034 2.44871   1.000 12.30532  ? 1314 VAL A CB    1 
ATOM   2755 C CG1   . VAL A 1 308 ? 12.48232  -22.34852 2.98604   1.000 13.12404  ? 1314 VAL A CG1   1 
ATOM   2756 C CG2   . VAL A 1 308 ? 14.21226  -21.78976 1.28850   1.000 13.51674  ? 1314 VAL A CG2   1 
ATOM   2757 N N     . GLU A 1 309 ? 14.07828  -22.88288 5.83076   1.000 11.42279  ? 1315 GLU A N     1 
ATOM   2758 C CA    . GLU A 1 309 ? 13.41919  -23.61172 6.91268   1.000 12.75638  ? 1315 GLU A CA    1 
ATOM   2759 C C     . GLU A 1 309 ? 12.26604  -22.74802 7.40329   1.000 12.80246  ? 1315 GLU A C     1 
ATOM   2760 O O     . GLU A 1 309 ? 12.46919  -21.80509 8.17198   1.000 13.05783  ? 1315 GLU A O     1 
ATOM   2761 C CB    . GLU A 1 309 ? 14.37324  -23.95875 8.04225   1.000 15.13628  ? 1315 GLU A CB    1 
ATOM   2762 C CG    . GLU A 1 309 ? 13.71165  -24.86507 9.07216   1.000 18.38116  ? 1315 GLU A CG    1 
ATOM   2763 C CD    . GLU A 1 309 ? 14.67216  -25.81480 9.74306   1.000 23.06490  ? 1315 GLU A CD    1 
ATOM   2764 O OE1   . GLU A 1 309 ? 15.41522  -25.34910 10.62170  1.000 23.33593  ? 1315 GLU A OE1   1 
ATOM   2765 O OE2   . GLU A 1 309 ? 14.66954  -27.02303 9.42204   1.000 27.64918  ? 1315 GLU A OE2   1 
ATOM   2766 N N     . VAL A 1 310 ? 11.06186  -23.05660 6.93285   1.000 13.49322  ? 1316 VAL A N     1 
ATOM   2767 C CA    . VAL A 1 310 ? 9.88329   -22.27918 7.27280   1.000 14.07948  ? 1316 VAL A CA    1 
ATOM   2768 C C     . VAL A 1 310 ? 8.82712   -23.22378 7.82124   1.000 15.09514  ? 1316 VAL A C     1 
ATOM   2769 O O     . VAL A 1 310 ? 8.85980   -24.43191 7.58363   1.000 16.58892  ? 1316 VAL A O     1 
ATOM   2770 C CB    . VAL A 1 310 ? 9.35999   -21.44385 6.08302   1.000 14.75461  ? 1316 VAL A CB    1 
ATOM   2771 C CG1   . VAL A 1 310 ? 10.39511  -20.38645 5.70996   1.000 15.17718  ? 1316 VAL A CG1   1 
ATOM   2772 C CG2   . VAL A 1 310 ? 9.01450   -22.34248 4.87823   1.000 15.29133  ? 1316 VAL A CG2   1 
ATOM   2773 N N     . TYR A 1 311 ? 7.89214   -22.66059 8.57210   1.000 15.23388  ? 1317 TYR A N     1 
ATOM   2774 C CA    . TYR A 1 311 ? 7.05964   -23.49118 9.42866   1.000 16.04151  ? 1317 TYR A CA    1 
ATOM   2775 C C     . TYR A 1 311 ? 5.72774   -22.83852 9.76896   1.000 17.98091  ? 1317 TYR A C     1 
ATOM   2776 O O     . TYR A 1 311 ? 5.37186   -21.80290 9.20133   1.000 18.23547  ? 1317 TYR A O     1 
ATOM   2777 C CB    . TYR A 1 311 ? 7.82201   -23.81815 10.71155  1.000 15.39608  ? 1317 TYR A CB    1 
ATOM   2778 C CG    . TYR A 1 311 ? 8.51947   -22.62597 11.32844  1.000 14.56229  ? 1317 TYR A CG    1 
ATOM   2779 C CD1   . TYR A 1 311 ? 7.80591   -21.67999 12.05639  1.000 14.49991  ? 1317 TYR A CD1   1 
ATOM   2780 C CD2   . TYR A 1 311 ? 9.88975   -22.44726 11.18898  1.000 12.97548  ? 1317 TYR A CD2   1 
ATOM   2781 C CE1   . TYR A 1 311 ? 8.43513   -20.58709 12.61493  1.000 14.05588  ? 1317 TYR A CE1   1 
ATOM   2782 C CE2   . TYR A 1 311 ? 10.52586  -21.35956 11.74444  1.000 12.26667  ? 1317 TYR A CE2   1 
ATOM   2783 C CZ    . TYR A 1 311 ? 9.79653   -20.42847 12.45788  1.000 12.33785  ? 1317 TYR A CZ    1 
ATOM   2784 O OH    . TYR A 1 311 ? 10.40208  -19.33191 13.01936  1.000 12.59880  ? 1317 TYR A OH    1 
ATOM   2785 O OXT   . TYR A 1 311 ? 4.98879   -23.34647 10.61738  1.000 19.39160  ? 1317 TYR A OXT   1 
HETATM 2786 O O1    A MES B 2 .   ? 6.03247   -24.03849 -2.83442  0.678 37.73477  ? 1401 MES A O1    1 
HETATM 2787 O O1    B MES B 2 .   ? 4.62665   -24.56327 -2.93819  0.322 41.17853  ? 1401 MES A O1    1 
HETATM 2788 C C2    A MES B 2 .   ? 6.55123   -23.89423 -1.51590  0.678 37.72334  ? 1401 MES A C2    1 
HETATM 2789 C C2    B MES B 2 .   ? 4.95056   -24.44233 -1.55555  0.322 41.91328  ? 1401 MES A C2    1 
HETATM 2790 C C3    A MES B 2 .   ? 7.75908   -24.80431 -1.32076  0.678 37.60374  ? 1401 MES A C3    1 
HETATM 2791 C C3    B MES B 2 .   ? 6.45700   -24.26779 -1.40781  0.322 43.07097  ? 1401 MES A C3    1 
HETATM 2792 N N4    A MES B 2 .   ? 7.63006   -25.92511 -2.24869  0.678 37.61084  ? 1401 MES A N4    1 
HETATM 2793 N N4    B MES B 2 .   ? 7.07573   -25.43360 -2.02247  0.322 44.07553  ? 1401 MES A N4    1 
HETATM 2794 C C5    A MES B 2 .   ? 6.29469   -26.45211 -2.50410  0.678 37.41280  ? 1401 MES A C5    1 
HETATM 2795 C C5    B MES B 2 .   ? 6.27709   -26.41049 -2.74996  0.322 42.53283  ? 1401 MES A C5    1 
HETATM 2796 C C6    A MES B 2 .   ? 5.44165   -25.31729 -3.06418  0.678 37.46352  ? 1401 MES A C6    1 
HETATM 2797 C C6    B MES B 2 .   ? 5.29676   -25.62716 -3.61882  0.322 41.51851  ? 1401 MES A C6    1 
HETATM 2798 C C7    A MES B 2 .   ? 8.71323   -26.90927 -2.29719  0.678 37.99789  ? 1401 MES A C7    1 
HETATM 2799 C C7    B MES B 2 .   ? 8.52781   -25.53611 -2.01225  0.322 46.65445  ? 1401 MES A C7    1 
HETATM 2800 C C8    A MES B 2 .   ? 9.85872   -26.44749 -1.39904  0.678 38.10687  ? 1401 MES A C8    1 
HETATM 2801 C C8    B MES B 2 .   ? 8.89461   -27.01561 -2.06601  0.322 48.89022  ? 1401 MES A C8    1 
HETATM 2802 S S     A MES B 2 .   ? 11.18502  -27.42649 -1.63908  0.678 37.82970  ? 1401 MES A S     1 
HETATM 2803 S S     B MES B 2 .   ? 10.39048  -27.13259 -2.78243  0.322 50.85905  ? 1401 MES A S     1 
HETATM 2804 O O1S   A MES B 2 .   ? 11.31222  -27.76663 -3.07490  0.678 39.09361  ? 1401 MES A O1S   1 
HETATM 2805 O O1S   B MES B 2 .   ? 10.95651  -25.77350 -2.93576  0.322 51.44798  ? 1401 MES A O1S   1 
HETATM 2806 O O2S   A MES B 2 .   ? 11.02509  -28.67327 -0.85612  0.678 36.61575  ? 1401 MES A O2S   1 
HETATM 2807 O O2S   B MES B 2 .   ? 10.26734  -27.76126 -4.11712  0.322 51.11324  ? 1401 MES A O2S   1 
HETATM 2808 O O3S   A MES B 2 .   ? 12.40329  -26.72233 -1.17436  0.678 38.72486  ? 1401 MES A O3S   1 
HETATM 2809 O O3S   B MES B 2 .   ? 11.28129  -27.96119 -1.93949  0.322 51.29396  ? 1401 MES A O3S   1 
HETATM 2810 O O1    . MES C 2 .   ? 20.25487  3.33145   -1.27590  1.000 131.13085 ? 1402 MES A O1    1 
HETATM 2811 C C2    . MES C 2 .   ? 21.01316  3.78972   -2.40018  1.000 95.47551  ? 1402 MES A C2    1 
HETATM 2812 C C3    . MES C 2 .   ? 21.90180  2.70897   -3.01564  1.000 58.98708  ? 1402 MES A C3    1 
HETATM 2813 N N4    . MES C 2 .   ? 21.05481  1.55627   -3.29339  1.000 101.98499 ? 1402 MES A N4    1 
HETATM 2814 C C5    . MES C 2 .   ? 19.92061  1.24210   -2.43421  1.000 115.04820 ? 1402 MES A C5    1 
HETATM 2815 C C6    . MES C 2 .   ? 20.23386  1.91493   -1.10221  1.000 32.61475  ? 1402 MES A C6    1 
HETATM 2816 C C7    . MES C 2 .   ? 21.24827  0.83319   -4.54261  1.000 36.90002  ? 1402 MES A C7    1 
HETATM 2817 C C8    . MES C 2 .   ? 21.11763  -0.65495  -4.22909  1.000 31.72275  ? 1402 MES A C8    1 
HETATM 2818 S S     . MES C 2 .   ? 21.17884  -1.48167  -5.67212  1.000 213.27755 ? 1402 MES A S     1 
HETATM 2819 O O1S   . MES C 2 .   ? 22.55555  -1.40855  -6.20348  1.000 60.68466  ? 1402 MES A O1S   1 
HETATM 2820 O O2S   . MES C 2 .   ? 20.25833  -0.85176  -6.64194  1.000 40.23903  ? 1402 MES A O2S   1 
HETATM 2821 O O3S   . MES C 2 .   ? 20.78862  -2.89883  -5.49690  1.000 18.46186  ? 1402 MES A O3S   1 
HETATM 2822 P PA    A FDA D 3 .   ? -0.18701  -26.60496 18.98833  0.583 9.40074   ? 1403 FDA A PA    1 
HETATM 2823 P PA    B FDA D 3 .   ? -0.35166  -25.94205 19.09052  0.417 9.36068   ? 1403 FDA A PA    1 
HETATM 2824 O O1A   A FDA D 3 .   ? 0.56226   -27.57266 18.16402  0.583 11.44285  ? 1403 FDA A O1A   1 
HETATM 2825 O O1A   B FDA D 3 .   ? 0.38236   -26.95225 18.29602  0.417 11.66486  ? 1403 FDA A O1A   1 
HETATM 2826 O O2A   A FDA D 3 .   ? -0.74688  -27.03117 20.29104  0.583 10.03876  ? 1403 FDA A O2A   1 
HETATM 2827 O O2A   B FDA D 3 .   ? -0.93085  -26.33819 20.39432  0.417 10.05649  ? 1403 FDA A O2A   1 
HETATM 2828 O O5B   A FDA D 3 .   ? -1.36917  -26.00695 18.12117  0.583 9.08125   ? 1403 FDA A O5B   1 
HETATM 2829 O O5B   B FDA D 3 .   ? -1.51510  -25.29561 18.20962  0.417 7.66659   ? 1403 FDA A O5B   1 
HETATM 2830 C C5B   A FDA D 3 .   ? -1.10885  -25.53153 16.78471  0.583 10.64452  ? 1403 FDA A C5B   1 
HETATM 2831 C C5B   B FDA D 3 .   ? -1.22954  -24.87561 16.86233  0.417 11.46956  ? 1403 FDA A C5B   1 
HETATM 2832 C C4B   A FDA D 3 .   ? -1.97712  -24.33684 16.47696  0.583 10.62918  ? 1403 FDA A C4B   1 
HETATM 2833 C C4B   B FDA D 3 .   ? -2.05306  -23.65390 16.53854  0.417 10.37821  ? 1403 FDA A C4B   1 
HETATM 2834 O O4B   A FDA D 3 .   ? -3.36567  -24.73624 16.45362  0.583 10.94203  ? 1403 FDA A O4B   1 
HETATM 2835 O O4B   B FDA D 3 .   ? -3.45465  -24.00091 16.47379  0.417 11.38368  ? 1403 FDA A O4B   1 
HETATM 2836 C C3B   A FDA D 3 .   ? -1.87529  -23.16691 17.46121  0.583 10.96115  ? 1403 FDA A C3B   1 
HETATM 2837 C C3B   B FDA D 3 .   ? -1.93928  -22.49485 17.53095  0.417 12.21021  ? 1403 FDA A C3B   1 
HETATM 2838 O O3B   A FDA D 3 .   ? -1.78193  -21.93367 16.75704  0.583 12.90165  ? 1403 FDA A O3B   1 
HETATM 2839 O O3B   B FDA D 3 .   ? -1.84554  -21.26156 16.82511  0.417 12.14628  ? 1403 FDA A O3B   1 
HETATM 2840 C C2B   A FDA D 3 .   ? -3.17997  -23.27052 18.25101  0.583 10.69044  ? 1403 FDA A C2B   1 
HETATM 2841 C C2B   B FDA D 3 .   ? -3.24911  -22.57942 18.31947  0.417 10.33769  ? 1403 FDA A C2B   1 
HETATM 2842 O O2B   A FDA D 3 .   ? -3.56806  -21.99635 18.75429  0.583 11.15401  ? 1403 FDA A O2B   1 
HETATM 2843 O O2B   B FDA D 3 .   ? -3.64027  -21.29458 18.79311  0.417 11.23625  ? 1403 FDA A O2B   1 
HETATM 2844 C C1B   A FDA D 3 .   ? -4.11642  -23.77434 17.16157  0.583 10.80350  ? 1403 FDA A C1B   1 
HETATM 2845 C C1B   B FDA D 3 .   ? -4.19932  -23.07062 17.23488  0.417 9.66201   ? 1403 FDA A C1B   1 
HETATM 2846 N N9A   A FDA D 3 .   ? -5.32785  -24.41655 17.64174  0.583 11.96523  ? 1403 FDA A N9A   1 
HETATM 2847 N N9A   B FDA D 3 .   ? -5.39588  -23.73977 17.73357  0.417 11.30534  ? 1403 FDA A N9A   1 
HETATM 2848 C C8A   A FDA D 3 .   ? -5.41908  -25.49872 18.47567  0.583 13.35573  ? 1403 FDA A C8A   1 
HETATM 2849 C C8A   B FDA D 3 .   ? -5.46800  -24.69005 18.71785  0.417 12.89613  ? 1403 FDA A C8A   1 
HETATM 2850 N N7A   A FDA D 3 .   ? -6.63999  -25.94098 18.64577  0.583 14.52833  ? 1403 FDA A N7A   1 
HETATM 2851 N N7A   B FDA D 3 .   ? -6.67808  -25.14480 18.93524  0.417 15.82363  ? 1403 FDA A N7A   1 
HETATM 2852 C C5A   A FDA D 3 .   ? -7.40965  -25.08796 17.86889  0.583 15.62242  ? 1403 FDA A C5A   1 
HETATM 2853 C C5A   B FDA D 3 .   ? -7.45971  -24.44429 18.02909  0.417 18.62263  ? 1403 FDA A C5A   1 
HETATM 2854 C C6A   A FDA D 3 .   ? -8.79082  -25.03342 17.60141  0.583 15.32756  ? 1403 FDA A C6A   1 
HETATM 2855 C C6A   B FDA D 3 .   ? -8.83751  -24.48002 17.73521  0.417 43.91033  ? 1403 FDA A C6A   1 
HETATM 2856 N N6A   A FDA D 3 .   ? -9.67773  -25.90300 18.09352  0.583 18.62284  ? 1403 FDA A N6A   1 
HETATM 2857 N N6A   B FDA D 3 .   ? -9.71390  -25.27085 18.36312  0.417 21.70552  ? 1403 FDA A N6A   1 
HETATM 2858 N N1A   A FDA D 3 .   ? -9.23198  -24.06341 16.77194  0.583 17.43830  ? 1403 FDA A N1A   1 
HETATM 2859 N N1A   B FDA D 3 .   ? -9.29142  -23.66904 16.75498  0.417 46.40963  ? 1403 FDA A N1A   1 
HETATM 2860 C C2A   A FDA D 3 .   ? -8.34520  -23.21385 16.24538  0.583 52.24692  ? 1403 FDA A C2A   1 
HETATM 2861 C C2A   B FDA D 3 .   ? -8.42081  -22.88045 16.11728  0.417 13.33753  ? 1403 FDA A C2A   1 
HETATM 2862 N N3A   A FDA D 3 .   ? -7.02228  -23.17004 16.42243  0.583 13.61783  ? 1403 FDA A N3A   1 
HETATM 2863 N N3A   B FDA D 3 .   ? -7.10386  -22.76074 16.30784  0.417 38.46891  ? 1403 FDA A N3A   1 
HETATM 2864 C C4A   A FDA D 3 .   ? -6.61382  -24.14154 17.24701  0.583 12.92766  ? 1403 FDA A C4A   1 
HETATM 2865 C C4A   B FDA D 3 .   ? -6.68261  -23.57361 17.28135  0.417 15.56049  ? 1403 FDA A C4A   1 
HETATM 2866 N N1    A FDA D 3 .   ? 7.95689   -21.77551 16.31041  0.583 8.96111   ? 1403 FDA A N1    1 
HETATM 2867 N N1    B FDA D 3 .   ? 7.88611   -21.18964 16.36885  0.417 8.01535   ? 1403 FDA A N1    1 
HETATM 2868 C C2    A FDA D 3 .   ? 8.39767   -20.68493 17.01744  0.583 8.72495   ? 1403 FDA A C2    1 
HETATM 2869 C C2    B FDA D 3 .   ? 8.33462   -20.09769 17.06531  0.417 8.65095   ? 1403 FDA A C2    1 
HETATM 2870 O O2    A FDA D 3 .   ? 7.63446   -19.97579 17.67083  0.583 8.91489   ? 1403 FDA A O2    1 
HETATM 2871 O O2    B FDA D 3 .   ? 7.56734   -19.34969 17.66357  0.417 8.36174   ? 1403 FDA A O2    1 
HETATM 2872 N N3    A FDA D 3 .   ? 9.74502   -20.44582 16.96403  0.583 8.43124   ? 1403 FDA A N3    1 
HETATM 2873 N N3    B FDA D 3 .   ? 9.68843   -19.87821 17.04093  0.417 7.25041   ? 1403 FDA A N3    1 
HETATM 2874 C C4    A FDA D 3 .   ? 10.68500  -21.18524 16.26797  0.583 7.42114   ? 1403 FDA A C4    1 
HETATM 2875 C C4    B FDA D 3 .   ? 10.63381  -20.61030 16.34513  0.417 7.76442   ? 1403 FDA A C4    1 
HETATM 2876 O O4    A FDA D 3 .   ? 11.86683  -20.85621 16.28993  0.583 7.84877   ? 1403 FDA A O4    1 
HETATM 2877 O O4    B FDA D 3 .   ? 11.81644  -20.26754 16.37349  0.417 8.04700   ? 1403 FDA A O4    1 
HETATM 2878 C C4X   A FDA D 3 .   ? 10.15565  -22.28861 15.57877  0.583 8.16891   ? 1403 FDA A C4X   1 
HETATM 2879 C C4X   B FDA D 3 .   ? 10.08283  -21.73071 15.64048  0.417 7.83525   ? 1403 FDA A C4X   1 
HETATM 2880 N N5    A FDA D 3 .   ? 11.01841  -23.06426 14.88751  0.583 8.05543   ? 1403 FDA A N5    1 
HETATM 2881 N N5    B FDA D 3 .   ? 10.91284  -22.53089 14.93609  0.417 10.13521  ? 1403 FDA A N5    1 
HETATM 2882 C C5X   A FDA D 3 .   ? 10.55024  -24.18847 14.21349  0.583 8.54892   ? 1403 FDA A C5X   1 
HETATM 2883 C C5X   B FDA D 3 .   ? 10.42434  -23.65907 14.26845  0.417 9.38353   ? 1403 FDA A C5X   1 
HETATM 2884 C C6    A FDA D 3 .   ? 11.43895  -24.97708 13.49489  0.583 9.12252   ? 1403 FDA A C6    1 
HETATM 2885 C C6    B FDA D 3 .   ? 11.28880  -24.45784 13.52719  0.417 11.07013  ? 1403 FDA A C6    1 
HETATM 2886 C C7    A FDA D 3 .   ? 10.99201  -26.08989 12.79364  0.583 10.90782  ? 1403 FDA A C7    1 
HETATM 2887 C C7    B FDA D 3 .   ? 10.81223  -25.56000 12.82521  0.417 11.31368  ? 1403 FDA A C7    1 
HETATM 2888 C C7M   A FDA D 3 .   ? 11.98122  -26.92313 12.02062  0.583 11.79578  ? 1403 FDA A C7M   1 
HETATM 2889 C C7M   B FDA D 3 .   ? 11.77064  -26.39330 12.01317  0.417 12.78488  ? 1403 FDA A C7M   1 
HETATM 2890 C C8    A FDA D 3 .   ? 9.62935   -26.41957 12.81598  0.583 11.03099  ? 1403 FDA A C8    1 
HETATM 2891 C C8    B FDA D 3 .   ? 9.44162   -25.87046 12.86876  0.417 9.87681   ? 1403 FDA A C8    1 
HETATM 2892 C C8M   A FDA D 3 .   ? 9.11349   -27.61870 12.06417  0.583 12.90479  ? 1403 FDA A C8M   1 
HETATM 2893 C C8M   B FDA D 3 .   ? 8.88787   -27.03349 12.08610  0.417 11.95423  ? 1403 FDA A C8M   1 
HETATM 2894 C C9    A FDA D 3 .   ? 8.74037   -25.62962 13.53874  0.583 10.44450  ? 1403 FDA A C9    1 
HETATM 2895 C C9    B FDA D 3 .   ? 8.57862   -25.07296 13.61448  0.417 10.15050  ? 1403 FDA A C9    1 
HETATM 2896 C C9A   A FDA D 3 .   ? 9.18611   -24.51672 14.24000  0.583 9.57227   ? 1403 FDA A C9A   1 
HETATM 2897 C C9A   B FDA D 3 .   ? 9.05612   -23.96973 14.31298  0.417 8.91131   ? 1403 FDA A C9A   1 
HETATM 2898 N N10   A FDA D 3 .   ? 8.30135   -23.70665 15.00128  0.583 8.87337   ? 1403 FDA A N10   1 
HETATM 2899 N N10   B FDA D 3 .   ? 8.19014   -23.13846 15.07197  0.417 8.51841   ? 1403 FDA A N10   1 
HETATM 2900 C C10   A FDA D 3 .   ? 8.81416   -22.58656 15.61956  0.583 8.29854   ? 1403 FDA A C10   1 
HETATM 2901 C C10   B FDA D 3 .   ? 8.72916   -22.01950 15.68349  0.417 8.97145   ? 1403 FDA A C10   1 
HETATM 2902 C "C1'" A FDA D 3 .   ? 6.89732   -24.10569 15.20975  0.583 8.44966   ? 1403 FDA A "C1'" 1 
HETATM 2903 C "C1'" B FDA D 3 .   ? 6.77656   -23.51155 15.28442  0.417 7.59817   ? 1403 FDA A "C1'" 1 
HETATM 2904 C "C2'" A FDA D 3 .   ? 6.75032   -24.94624 16.47839  0.583 7.90058   ? 1403 FDA A "C2'" 1 
HETATM 2905 C "C2'" B FDA D 3 .   ? 6.60173   -24.35640 16.54760  0.417 7.57012   ? 1403 FDA A "C2'" 1 
HETATM 2906 O "O2'" A FDA D 3 .   ? 7.30189   -26.24428 16.26924  0.583 9.21981   ? 1403 FDA A "O2'" 1 
HETATM 2907 O "O2'" B FDA D 3 .   ? 7.13037   -25.66599 16.33860  0.417 7.42386   ? 1403 FDA A "O2'" 1 
HETATM 2908 C "C3'" A FDA D 3 .   ? 5.26963   -25.13434 16.82951  0.583 8.35376   ? 1403 FDA A "C3'" 1 
HETATM 2909 C "C3'" B FDA D 3 .   ? 5.11487   -24.51736 16.88770  0.417 6.39751   ? 1403 FDA A "C3'" 1 
HETATM 2910 O "O3'" A FDA D 3 .   ? 4.55961   -25.72481 15.74649  0.583 9.17429   ? 1403 FDA A "O3'" 1 
HETATM 2911 O "O3'" B FDA D 3 .   ? 4.41543   -25.05131 15.76987  0.417 7.90328   ? 1403 FDA A "O3'" 1 
HETATM 2912 C "C4'" A FDA D 3 .   ? 4.54948   -23.85974 17.27336  0.583 7.91134   ? 1403 FDA A "C4'" 1 
HETATM 2913 C "C4'" B FDA D 3 .   ? 4.42329   -23.23850 17.36650  0.417 7.60025   ? 1403 FDA A "C4'" 1 
HETATM 2914 O "O4'" A FDA D 3 .   ? 5.25941   -23.27284 18.36469  0.583 8.45069   ? 1403 FDA A "O4'" 1 
HETATM 2915 O "O4'" B FDA D 3 .   ? 5.17775   -22.64317 18.42282  0.417 8.53329   ? 1403 FDA A "O4'" 1 
HETATM 2916 C "C5'" A FDA D 3 .   ? 3.12163   -24.15137 17.68999  0.583 8.88259   ? 1403 FDA A "C5'" 1 
HETATM 2917 C "C5'" B FDA D 3 .   ? 3.00727   -23.50099 17.83652  0.417 8.31660   ? 1403 FDA A "C5'" 1 
HETATM 2918 O "O5'" A FDA D 3 .   ? 3.14168   -25.23453 18.64634  0.583 8.23415   ? 1403 FDA A "O5'" 1 
HETATM 2919 O "O5'" B FDA D 3 .   ? 3.04358   -24.59670 18.77263  0.417 7.80383   ? 1403 FDA A "O5'" 1 
HETATM 2920 P P     A FDA D 3 .   ? 2.16439   -25.24580 19.89658  0.583 8.60290   ? 1403 FDA A P     1 
HETATM 2921 P P     B FDA D 3 .   ? 2.05344   -24.62317 20.00900  0.417 7.36332   ? 1403 FDA A P     1 
HETATM 2922 O O1P   A FDA D 3 .   ? 2.38550   -26.49388 20.65480  0.583 9.38861   ? 1403 FDA A O1P   1 
HETATM 2923 O O1P   B FDA D 3 .   ? 2.26186   -25.89594 20.73557  0.417 9.23241   ? 1403 FDA A O1P   1 
HETATM 2924 O O2P   A FDA D 3 .   ? 2.21209   -23.94245 20.60112  0.583 7.87074   ? 1403 FDA A O2P   1 
HETATM 2925 O O2P   B FDA D 3 .   ? 2.13875   -23.34468 20.75414  0.417 8.76945   ? 1403 FDA A O2P   1 
HETATM 2926 O O3P   A FDA D 3 .   ? 0.74385   -25.32393 19.18253  0.583 9.10135   ? 1403 FDA A O3P   1 
HETATM 2927 O O3P   B FDA D 3 .   ? 0.62581   -24.69275 19.29527  0.417 7.08373   ? 1403 FDA A O3P   1 
HETATM 2928 O O1    . MES E 2 .   ? 4.59158   -10.68260 8.65845   1.000 42.87336  ? 1404 MES A O1    1 
HETATM 2929 C C2    . MES E 2 .   ? 5.89707   -10.47419 9.20586   1.000 58.11892  ? 1404 MES A C2    1 
HETATM 2930 C C3    . MES E 2 .   ? 5.93224   -10.59184 10.72935  1.000 46.74305  ? 1404 MES A C3    1 
HETATM 2931 N N4    . MES E 2 .   ? 5.35563   -11.88497 11.07914  1.000 79.83345  ? 1404 MES A N4    1 
HETATM 2932 C C5    . MES E 2 .   ? 4.28724   -12.45766 10.26825  1.000 64.65189  ? 1404 MES A C5    1 
HETATM 2933 C C6    . MES E 2 .   ? 3.65100   -11.26586 9.56088   1.000 77.22583  ? 1404 MES A C6    1 
HETATM 2934 C C7    . MES E 2 .   ? 5.99194   -12.64179 12.15250  1.000 78.00255  ? 1404 MES A C7    1 
HETATM 2935 C C8    . MES E 2 .   ? 5.21594   -13.93355 12.39157  1.000 55.50042  ? 1404 MES A C8    1 
HETATM 2936 S S     . MES E 2 .   ? 5.80597   -14.65473 13.77104  1.000 89.48978  ? 1404 MES A S     1 
HETATM 2937 O O1S   . MES E 2 .   ? 4.89639   -15.74274 14.19484  1.000 62.07417  ? 1404 MES A O1S   1 
HETATM 2938 O O2S   . MES E 2 .   ? 5.87473   -13.63865 14.84254  1.000 33.64770  ? 1404 MES A O2S   1 
HETATM 2939 O O3S   . MES E 2 .   ? 7.15384   -15.22637 13.51865  1.000 16.07098  ? 1404 MES A O3S   1 
HETATM 2940 O O     . HOH F 4 .   ? 1.22883   -1.14408  7.23434   1.000 62.68053  ? 1501 HOH A O     1 
HETATM 2941 O O     . HOH F 4 .   ? 5.02649   -20.37463 18.20930  1.000 16.63820  ? 1502 HOH A O     1 
HETATM 2942 O O     . HOH F 4 .   ? -13.73238 -20.89652 21.08906  1.000 24.41254  ? 1503 HOH A O     1 
HETATM 2943 O O     . HOH F 4 .   ? 7.32860   -6.90169  7.46952   1.000 26.29096  ? 1504 HOH A O     1 
HETATM 2944 O O     . HOH F 4 .   ? 10.95266  -2.31341  -2.97556  1.000 30.77507  ? 1505 HOH A O     1 
HETATM 2945 O O     . HOH F 4 .   ? 7.51974   -12.34991 3.13509   1.000 25.21314  ? 1506 HOH A O     1 
HETATM 2946 O O     . HOH F 4 .   ? 37.13742  -4.41002  5.70899   1.000 41.95200  ? 1507 HOH A O     1 
HETATM 2947 O O     . HOH F 4 .   ? 18.72682  -2.27937  -7.76140  1.000 39.27157  ? 1508 HOH A O     1 
HETATM 2948 O O     A HOH F 4 .   ? 6.76636   -28.51376 15.66621  0.595 12.43318  ? 1509 HOH A O     1 
HETATM 2949 O O     B HOH F 4 .   ? 6.91543   -28.68789 15.01026  0.405 23.56028  ? 1509 HOH A O     1 
HETATM 2950 O O     . HOH F 4 .   ? 16.73212  -0.09411  5.29981   1.000 24.46441  ? 1510 HOH A O     1 
HETATM 2951 O O     . HOH F 4 .   ? 13.44341  0.06137   8.14181   1.000 35.38775  ? 1511 HOH A O     1 
HETATM 2952 O O     . HOH F 4 .   ? 37.55527  -9.90583  4.30713   1.000 38.04996  ? 1512 HOH A O     1 
HETATM 2953 O O     . HOH F 4 .   ? 1.62045   -13.89977 20.16923  1.000 45.03467  ? 1513 HOH A O     1 
HETATM 2954 O O     . HOH F 4 .   ? 2.97095   -11.64917 -3.74980  1.000 51.44788  ? 1514 HOH A O     1 
HETATM 2955 O O     . HOH F 4 .   ? 4.74275   -16.97938 -5.26268  1.000 29.62242  ? 1515 HOH A O     1 
HETATM 2956 O O     . HOH F 4 .   ? 27.68378  -3.28164  -3.37398  1.000 52.96037  ? 1516 HOH A O     1 
HETATM 2957 O O     . HOH F 4 .   ? -5.91581  -21.16061 14.83091  1.000 31.46374  ? 1517 HOH A O     1 
HETATM 2958 O O     . HOH F 4 .   ? 9.70739   -21.07558 -9.63662  1.000 53.09090  ? 1518 HOH A O     1 
HETATM 2959 O O     . HOH F 4 .   ? -0.45535  -29.70997 17.35075  1.000 31.35472  ? 1519 HOH A O     1 
HETATM 2960 O O     . HOH F 4 .   ? -17.18192 -15.55586 20.40173  1.000 26.52803  ? 1520 HOH A O     1 
HETATM 2961 O O     . HOH F 4 .   ? -3.38725  -32.74391 27.06842  1.000 20.01467  ? 1521 HOH A O     1 
HETATM 2962 O O     . HOH F 4 .   ? 8.78838   -7.86120  -13.88946 1.000 45.53161  ? 1522 HOH A O     1 
HETATM 2963 O O     . HOH F 4 .   ? 4.32943   -14.77237 -9.01032  1.000 38.70994  ? 1523 HOH A O     1 
HETATM 2964 O O     . HOH F 4 .   ? -14.001   -19.059   25.186    1.000 30.06576  ? 1524 HOH A O     1 
HETATM 2965 O O     . HOH F 4 .   ? 30.75230  -24.93606 1.41153   1.000 30.05791  ? 1525 HOH A O     1 
HETATM 2966 O O     . HOH F 4 .   ? 7.66735   -38.52479 25.18731  1.000 36.96170  ? 1526 HOH A O     1 
HETATM 2967 O O     . HOH F 4 .   ? 7.73382   -26.64642 8.07280   1.000 40.70129  ? 1527 HOH A O     1 
HETATM 2968 O O     . HOH F 4 .   ? 5.95904   -14.02173 29.22961  1.000 40.75813  ? 1528 HOH A O     1 
HETATM 2969 O O     . HOH F 4 .   ? -4.90236  -26.09576 21.92838  1.000 47.52339  ? 1529 HOH A O     1 
HETATM 2970 O O     . HOH F 4 .   ? 16.77718  -26.24787 12.56943  1.000 24.63063  ? 1530 HOH A O     1 
HETATM 2971 O O     . HOH F 4 .   ? 9.30999   -14.80612 -15.33156 1.000 49.70758  ? 1531 HOH A O     1 
HETATM 2972 O O     . HOH F 4 .   ? -3.29518  -19.12113 17.46560  1.000 35.22547  ? 1532 HOH A O     1 
HETATM 2973 O O     . HOH F 4 .   ? 35.94459  -27.83289 13.80291  1.000 44.83678  ? 1533 HOH A O     1 
HETATM 2974 O O     . HOH F 4 .   ? 5.37494   1.27746   22.38026  1.000 37.52982  ? 1534 HOH A O     1 
HETATM 2975 O O     . HOH F 4 .   ? 13.48018  -26.50490 3.00845   1.000 41.79783  ? 1535 HOH A O     1 
HETATM 2976 O O     . HOH F 4 .   ? 39.75936  -29.77069 18.51707  1.000 48.43147  ? 1536 HOH A O     1 
HETATM 2977 O O     . HOH F 4 .   ? 5.36893   -26.57235 13.43865  1.000 42.40214  ? 1537 HOH A O     1 
HETATM 2978 O O     . HOH F 4 .   ? 12.86151  -19.77376 13.74955  1.000 13.06689  ? 1538 HOH A O     1 
HETATM 2979 O O     . HOH F 4 .   ? 8.05708   -9.26556  6.10949   1.000 22.84975  ? 1539 HOH A O     1 
HETATM 2980 O O     . HOH F 4 .   ? 36.16468  -22.65227 8.38937   1.000 25.84974  ? 1540 HOH A O     1 
HETATM 2981 O O     . HOH F 4 .   ? -11.90730 -13.72745 26.19641  1.000 45.81220  ? 1541 HOH A O     1 
HETATM 2982 O O     . HOH F 4 .   ? 33.40340  -14.15994 15.96021  1.000 12.04418  ? 1542 HOH A O     1 
HETATM 2983 O O     . HOH F 4 .   ? 2.41774   -27.10775 16.31270  1.000 17.27202  ? 1543 HOH A O     1 
HETATM 2984 O O     . HOH F 4 .   ? 13.15699  -20.76233 18.79703  1.000 10.92300  ? 1544 HOH A O     1 
HETATM 2985 O O     . HOH F 4 .   ? 22.06502  -11.35907 -12.08816 1.000 32.81853  ? 1545 HOH A O     1 
HETATM 2986 O O     . HOH F 4 .   ? 25.64709  -36.59363 12.89573  1.000 44.13453  ? 1546 HOH A O     1 
HETATM 2987 O O     . HOH F 4 .   ? 4.05380   -14.08396 1.21676   1.000 25.16225  ? 1547 HOH A O     1 
HETATM 2988 O O     . HOH F 4 .   ? 16.05710  -43.18258 23.97843  1.000 37.59372  ? 1548 HOH A O     1 
HETATM 2989 O O     . HOH F 4 .   ? 19.61196  -44.48857 17.24285  1.000 40.77361  ? 1549 HOH A O     1 
HETATM 2990 O O     . HOH F 4 .   ? 17.79928  -17.97829 36.59345  1.000 33.37832  ? 1550 HOH A O     1 
HETATM 2991 O O     . HOH F 4 .   ? 8.80841   -6.48549  -3.55130  1.000 30.86076  ? 1551 HOH A O     1 
HETATM 2992 O O     . HOH F 4 .   ? 5.85085   -16.67665 -7.94701  1.000 38.52222  ? 1552 HOH A O     1 
HETATM 2993 O O     . HOH F 4 .   ? 23.89359  0.34289   -1.61365  1.000 41.53430  ? 1553 HOH A O     1 
HETATM 2994 O O     . HOH F 4 .   ? -12.91458 -16.28114 26.57416  1.000 35.21750  ? 1554 HOH A O     1 
HETATM 2995 O O     . HOH F 4 .   ? 28.93308  -1.72005  19.06984  1.000 40.74428  ? 1555 HOH A O     1 
HETATM 2996 O O     . HOH F 4 .   ? -8.76829  -16.56931 14.72939  1.000 48.00314  ? 1556 HOH A O     1 
HETATM 2997 O O     A HOH F 4 .   ? 27.87584  -22.76100 12.56128  0.623 10.89129  ? 1557 HOH A O     1 
HETATM 2998 O O     B HOH F 4 .   ? 28.29031  -23.66969 13.02193  0.377 13.32617  ? 1557 HOH A O     1 
HETATM 2999 O O     . HOH F 4 .   ? 5.68562   -10.83230 18.78874  1.000 17.33321  ? 1558 HOH A O     1 
HETATM 3000 O O     . HOH F 4 .   ? 13.50710  -37.36766 30.92168  1.000 33.62872  ? 1559 HOH A O     1 
HETATM 3001 O O     . HOH F 4 .   ? -14.55152 -19.24957 18.52947  1.000 27.85370  ? 1560 HOH A O     1 
HETATM 3002 O O     . HOH F 4 .   ? 15.01499  -31.95457 17.65972  1.000 18.04528  ? 1561 HOH A O     1 
HETATM 3003 O O     . HOH F 4 .   ? 21.19583  -38.04558 30.24223  1.000 24.26924  ? 1562 HOH A O     1 
HETATM 3004 O O     . HOH F 4 .   ? 23.78906  -8.01520  22.59583  1.000 24.97345  ? 1563 HOH A O     1 
HETATM 3005 O O     . HOH F 4 .   ? 38.48314  -14.62837 7.21437   1.000 20.88534  ? 1564 HOH A O     1 
HETATM 3006 O O     . HOH F 4 .   ? 30.75655  -26.12066 7.18594   1.000 18.93097  ? 1565 HOH A O     1 
HETATM 3007 O O     . HOH F 4 .   ? 34.69552  -15.97953 -1.02137  1.000 33.80919  ? 1566 HOH A O     1 
HETATM 3008 O O     . HOH F 4 .   ? 6.38920   -37.35976 22.13767  1.000 44.57638  ? 1567 HOH A O     1 
HETATM 3009 O O     . HOH F 4 .   ? 25.46290  -20.64948 27.62771  1.000 8.96125   ? 1568 HOH A O     1 
HETATM 3010 O O     . HOH F 4 .   ? 22.73753  -24.64414 5.17017   1.000 18.02550  ? 1569 HOH A O     1 
HETATM 3011 O O     . HOH F 4 .   ? 29.40377  -8.06927  19.40430  1.000 32.18278  ? 1570 HOH A O     1 
HETATM 3012 O O     . HOH F 4 .   ? 7.87325   -12.73506 16.37296  1.000 16.29052  ? 1571 HOH A O     1 
HETATM 3013 O O     . HOH F 4 .   ? 26.09961  -10.72869 -11.79138 1.000 21.00840  ? 1572 HOH A O     1 
HETATM 3014 O O     . HOH F 4 .   ? 3.53843   -34.87453 27.42597  1.000 14.76860  ? 1573 HOH A O     1 
HETATM 3015 O O     . HOH F 4 .   ? 21.76092  -18.52079 -10.22023 1.000 50.81590  ? 1574 HOH A O     1 
HETATM 3016 O O     . HOH F 4 .   ? 16.69347  -28.75232 9.12069   1.000 26.59888  ? 1575 HOH A O     1 
HETATM 3017 O O     . HOH F 4 .   ? 12.47635  -1.53961  -7.41331  1.000 65.25241  ? 1576 HOH A O     1 
HETATM 3018 O O     . HOH F 4 .   ? 0.42166   -24.78357 27.62770  1.000 13.16732  ? 1577 HOH A O     1 
HETATM 3019 O O     . HOH F 4 .   ? 19.37523  -15.47926 31.18418  1.000 21.97925  ? 1578 HOH A O     1 
HETATM 3020 O O     . HOH F 4 .   ? 37.96666  -20.86664 26.09733  1.000 12.42683  ? 1579 HOH A O     1 
HETATM 3021 O O     . HOH F 4 .   ? 23.75954  -33.45632 21.51362  1.000 12.53052  ? 1580 HOH A O     1 
HETATM 3022 O O     . HOH F 4 .   ? 7.13376   -16.52909 31.92414  1.000 13.60326  ? 1581 HOH A O     1 
HETATM 3023 O O     . HOH F 4 .   ? 20.74878  -25.50345 -1.25593  1.000 24.75878  ? 1582 HOH A O     1 
HETATM 3024 O O     . HOH F 4 .   ? 38.02079  -24.33351 4.99450   1.000 38.60706  ? 1583 HOH A O     1 
HETATM 3025 O O     . HOH F 4 .   ? 20.54390  -8.33178  -16.19533 1.000 40.10499  ? 1584 HOH A O     1 
HETATM 3026 O O     . HOH F 4 .   ? 23.38717  -29.13479 5.59636   1.000 25.64089  ? 1585 HOH A O     1 
HETATM 3027 O O     . HOH F 4 .   ? 13.63427  -34.10961 18.58460  1.000 21.95326  ? 1586 HOH A O     1 
HETATM 3028 O O     . HOH F 4 .   ? 39.55124  -23.48676 10.68794  1.000 40.54424  ? 1587 HOH A O     1 
HETATM 3029 O O     . HOH F 4 .   ? 26.64489  -16.50623 22.73542  1.000 9.57751   ? 1588 HOH A O     1 
HETATM 3030 O O     . HOH F 4 .   ? 24.34419  -37.31154 19.39888  1.000 29.21373  ? 1589 HOH A O     1 
HETATM 3031 O O     . HOH F 4 .   ? 27.36491  -28.03075 24.97113  1.000 10.36133  ? 1590 HOH A O     1 
HETATM 3032 O O     . HOH F 4 .   ? 16.69573  -40.45152 24.51046  1.000 16.10067  ? 1591 HOH A O     1 
HETATM 3033 O O     . HOH F 4 .   ? 24.80735  -36.24857 25.99597  1.000 33.20607  ? 1592 HOH A O     1 
HETATM 3034 O O     . HOH F 4 .   ? 16.50634  -30.71128 35.11413  1.000 23.86905  ? 1593 HOH A O     1 
HETATM 3035 O O     . HOH F 4 .   ? 28.12171  -25.87389 10.12405  1.000 12.45026  ? 1594 HOH A O     1 
HETATM 3036 O O     . HOH F 4 .   ? -11.93135 -23.12267 16.58113  1.000 22.26974  ? 1595 HOH A O     1 
HETATM 3037 O O     . HOH F 4 .   ? 31.67874  -19.09764 -0.69032  1.000 17.81510  ? 1596 HOH A O     1 
HETATM 3038 O O     . HOH F 4 .   ? 34.37588  -9.81226  10.35067  1.000 27.80215  ? 1597 HOH A O     1 
HETATM 3039 O O     A HOH F 4 .   ? 9.02432   -37.40401 29.22683  0.447 24.88052  ? 1598 HOH A O     1 
HETATM 3040 O O     B HOH F 4 .   ? 7.93474   -36.94558 27.98905  0.553 31.27422  ? 1598 HOH A O     1 
HETATM 3041 O O     . HOH F 4 .   ? -13.45661 -18.01973 21.54009  1.000 40.71061  ? 1599 HOH A O     1 
HETATM 3042 O O     . HOH F 4 .   ? 31.65697  -24.51685 30.70603  1.000 14.02083  ? 1600 HOH A O     1 
HETATM 3043 O O     . HOH F 4 .   ? 27.48517  -1.79279  7.32732   1.000 14.86370  ? 1601 HOH A O     1 
HETATM 3044 O O     . HOH F 4 .   ? 22.98751  -16.66902 -9.07846  1.000 23.74840  ? 1602 HOH A O     1 
HETATM 3045 O O     . HOH F 4 .   ? 28.61868  -34.68054 16.93775  1.000 28.06788  ? 1603 HOH A O     1 
HETATM 3046 O O     A HOH F 4 .   ? 5.33697   -8.61822  26.10343  0.541 22.08371  ? 1604 HOH A O     1 
HETATM 3047 O O     B HOH F 4 .   ? 6.02575   -7.31703  26.21775  0.459 26.10160  ? 1604 HOH A O     1 
HETATM 3048 O O     . HOH F 4 .   ? 25.52823  -36.50450 28.46480  1.000 43.91789  ? 1605 HOH A O     1 
HETATM 3049 O O     . HOH F 4 .   ? 14.86018  -26.50965 39.25473  1.000 17.01882  ? 1606 HOH A O     1 
HETATM 3050 O O     . HOH F 4 .   ? 23.54623  -12.13064 16.91357  1.000 10.05623  ? 1607 HOH A O     1 
HETATM 3051 O O     . HOH F 4 .   ? 38.07765  -17.43742 1.26044   1.000 26.97905  ? 1608 HOH A O     1 
HETATM 3052 O O     . HOH F 4 .   ? 29.18573  -21.96228 33.62387  1.000 12.77294  ? 1609 HOH A O     1 
HETATM 3053 O O     . HOH F 4 .   ? 33.78169  -35.92319 14.90667  1.000 45.39364  ? 1610 HOH A O     1 
HETATM 3054 O O     . HOH F 4 .   ? 0.59380   -33.46752 21.21526  1.000 17.88421  ? 1611 HOH A O     1 
HETATM 3055 O O     . HOH F 4 .   ? 15.38790  -15.08715 28.79369  1.000 13.18684  ? 1612 HOH A O     1 
HETATM 3056 O O     . HOH F 4 .   ? 3.11003   -23.82567 13.71801  1.000 46.43753  ? 1613 HOH A O     1 
HETATM 3057 O O     . HOH F 4 .   ? 11.00483  -4.98318  20.34464  1.000 22.11874  ? 1614 HOH A O     1 
HETATM 3058 O O     . HOH F 4 .   ? 2.73085   -21.13764 9.25403   1.000 23.13422  ? 1615 HOH A O     1 
HETATM 3059 O O     . HOH F 4 .   ? 20.08024  -26.03511 3.07382   1.000 18.41198  ? 1616 HOH A O     1 
HETATM 3060 O O     . HOH F 4 .   ? 24.67591  -13.20438 26.07372  1.000 11.63929  ? 1617 HOH A O     1 
HETATM 3061 O O     . HOH F 4 .   ? 25.24489  -24.65581 24.87932  1.000 10.30052  ? 1618 HOH A O     1 
HETATM 3062 O O     . HOH F 4 .   ? 3.78770   -17.99926 34.23562  1.000 21.41414  ? 1619 HOH A O     1 
HETATM 3063 O O     . HOH F 4 .   ? 19.62601  -0.96729  9.81182   1.000 27.08646  ? 1620 HOH A O     1 
HETATM 3064 O O     . HOH F 4 .   ? 22.24776  -2.41721  3.76803   1.000 15.84830  ? 1621 HOH A O     1 
HETATM 3065 O O     . HOH F 4 .   ? 28.73545  -20.71655 -3.30403  1.000 17.53337  ? 1622 HOH A O     1 
HETATM 3066 O O     . HOH F 4 .   ? 15.38017  -6.68607  15.35426  1.000 16.21280  ? 1623 HOH A O     1 
HETATM 3067 O O     . HOH F 4 .   ? 37.97702  -12.17763 24.96408  1.000 37.17035  ? 1624 HOH A O     1 
HETATM 3068 O O     . HOH F 4 .   ? 34.98113  -23.66946 10.54515  1.000 27.83319  ? 1625 HOH A O     1 
HETATM 3069 O O     . HOH F 4 .   ? 26.21113  -24.76619 11.77233  1.000 10.99896  ? 1626 HOH A O     1 
HETATM 3070 O O     . HOH F 4 .   ? 30.69918  -10.19512 -0.67926  1.000 22.53314  ? 1627 HOH A O     1 
HETATM 3071 O O     . HOH F 4 .   ? 32.95693  -31.36558 19.90191  1.000 19.25829  ? 1628 HOH A O     1 
HETATM 3072 O O     . HOH F 4 .   ? 7.23660   -24.29742 32.75446  1.000 10.53751  ? 1629 HOH A O     1 
HETATM 3073 O O     . HOH F 4 .   ? 33.97356  -4.44613  9.37632   1.000 13.95728  ? 1630 HOH A O     1 
HETATM 3074 O O     . HOH F 4 .   ? -1.47475  -34.15036 19.52916  1.000 37.04881  ? 1631 HOH A O     1 
HETATM 3075 O O     A HOH F 4 .   ? 14.58656  -31.32191 12.52457  0.521 13.45537  ? 1632 HOH A O     1 
HETATM 3076 O O     B HOH F 4 .   ? 14.50075  -30.18799 12.59591  0.479 24.66380  ? 1632 HOH A O     1 
HETATM 3077 O O     A HOH F 4 .   ? 34.64516  -14.73838 13.14779  0.583 10.23342  ? 1633 HOH A O     1 
HETATM 3078 O O     B HOH F 4 .   ? 34.13978  -15.49043 13.29383  0.417 22.67115  ? 1633 HOH A O     1 
HETATM 3079 O O     . HOH F 4 .   ? -3.49770  -27.32177 20.46590  1.000 28.66869  ? 1634 HOH A O     1 
HETATM 3080 O O     . HOH F 4 .   ? 20.49526  -11.05571 22.08709  1.000 12.69001  ? 1635 HOH A O     1 
HETATM 3081 O O     . HOH F 4 .   ? 0.84305   -21.74439 15.95702  1.000 19.74339  ? 1636 HOH A O     1 
HETATM 3082 O O     . HOH F 4 .   ? -0.68993  -3.08780  17.92731  1.000 41.52944  ? 1637 HOH A O     1 
HETATM 3083 O O     . HOH F 4 .   ? 18.35370  -27.54541 -9.61976  1.000 14.99204  ? 1638 HOH A O     1 
HETATM 3084 O O     . HOH F 4 .   ? -16.65715 -17.14802 14.79651  1.000 19.86962  ? 1639 HOH A O     1 
HETATM 3085 O O     . HOH F 4 .   ? 12.58170  1.18725   14.96405  1.000 46.59340  ? 1640 HOH A O     1 
HETATM 3086 O O     A HOH F 4 .   ? 37.03987  -17.91986 23.30075  0.668 13.52687  ? 1641 HOH A O     1 
HETATM 3087 O O     B HOH F 4 .   ? 37.64353  -18.36119 23.25291  0.332 19.84956  ? 1641 HOH A O     1 
HETATM 3088 O O     . HOH F 4 .   ? 38.47981  -32.56933 15.19115  1.000 53.55844  ? 1642 HOH A O     1 
HETATM 3089 O O     . HOH F 4 .   ? 22.56422  -40.22233 23.11519  1.000 55.18178  ? 1643 HOH A O     1 
HETATM 3090 O O     . HOH F 4 .   ? -20.02020 -11.54696 21.94546  1.000 38.17206  ? 1644 HOH A O     1 
HETATM 3091 O O     . HOH F 4 .   ? 29.89857  -20.38849 17.95417  1.000 9.26866   ? 1645 HOH A O     1 
HETATM 3092 O O     . HOH F 4 .   ? -15.19499 -24.86537 19.48892  1.000 45.96658  ? 1646 HOH A O     1 
HETATM 3093 O O     . HOH F 4 .   ? 39.44249  -23.70176 18.39143  1.000 23.95305  ? 1647 HOH A O     1 
HETATM 3094 O O     . HOH F 4 .   ? 5.82212   -9.20901  -4.43317  1.000 37.11432  ? 1648 HOH A O     1 
HETATM 3095 O O     . HOH F 4 .   ? 14.26107  -27.82005 -2.89292  1.000 55.00977  ? 1649 HOH A O     1 
HETATM 3096 O O     . HOH F 4 .   ? 40.93187  -19.59600 11.81075  1.000 19.58358  ? 1650 HOH A O     1 
HETATM 3097 O O     . HOH F 4 .   ? 7.76329   -26.86951 33.55499  1.000 10.25549  ? 1651 HOH A O     1 
HETATM 3098 O O     . HOH F 4 .   ? 14.99920  -1.01475  18.77998  1.000 36.68246  ? 1652 HOH A O     1 
HETATM 3099 O O     . HOH F 4 .   ? 17.48890  -31.30451 8.04330   1.000 34.01856  ? 1653 HOH A O     1 
HETATM 3100 O O     . HOH F 4 .   ? -12.28758 -25.99852 17.19024  1.000 57.51892  ? 1654 HOH A O     1 
HETATM 3101 O O     . HOH F 4 .   ? 23.39860  -30.29319 -6.33285  1.000 51.44667  ? 1655 HOH A O     1 
HETATM 3102 O O     . HOH F 4 .   ? 14.02420  -7.75413  21.27956  1.000 12.73521  ? 1656 HOH A O     1 
HETATM 3103 O O     . HOH F 4 .   ? 31.26043  -19.05664 6.11075   1.000 10.56135  ? 1657 HOH A O     1 
HETATM 3104 O O     . HOH F 4 .   ? 28.69631  -30.39550 25.45402  1.000 12.06347  ? 1658 HOH A O     1 
HETATM 3105 O O     . HOH F 4 .   ? 9.39933   -10.28472 30.08122  1.000 34.09499  ? 1659 HOH A O     1 
HETATM 3106 O O     . HOH F 4 .   ? -15.40636 -21.58622 17.88771  1.000 32.54827  ? 1660 HOH A O     1 
HETATM 3107 O O     . HOH F 4 .   ? 35.60062  -4.25790  12.16012  1.000 41.66680  ? 1661 HOH A O     1 
HETATM 3108 O O     . HOH F 4 .   ? 21.79646  -19.85764 25.42075  1.000 9.89716   ? 1662 HOH A O     1 
HETATM 3109 O O     . HOH F 4 .   ? 33.26770  -17.89179 28.51185  1.000 15.13003  ? 1663 HOH A O     1 
HETATM 3110 O O     . HOH F 4 .   ? 6.50350   -18.06604 14.70278  1.000 17.93470  ? 1664 HOH A O     1 
HETATM 3111 O O     . HOH F 4 .   ? 14.02315  -8.70411  26.12557  1.000 22.94622  ? 1665 HOH A O     1 
HETATM 3112 O O     . HOH F 4 .   ? 8.55977   -30.03627 28.98068  1.000 14.32931  ? 1666 HOH A O     1 
HETATM 3113 O O     . HOH F 4 .   ? 8.19194   -10.10302 15.60560  1.000 26.22317  ? 1667 HOH A O     1 
HETATM 3114 O O     . HOH F 4 .   ? 33.07319  0.02058   16.75715  1.000 48.23906  ? 1668 HOH A O     1 
HETATM 3115 O O     . HOH F 4 .   ? 11.26347  -18.98615 39.49052  1.000 18.86177  ? 1669 HOH A O     1 
HETATM 3116 O O     . HOH F 4 .   ? -1.39252  -31.03272 21.87169  1.000 19.39230  ? 1670 HOH A O     1 
HETATM 3117 O O     . HOH F 4 .   ? 22.04708  -22.76662 35.30960  1.000 40.42447  ? 1671 HOH A O     1 
HETATM 3118 O O     . HOH F 4 .   ? 34.08809  -26.33555 14.19381  1.000 20.76316  ? 1672 HOH A O     1 
HETATM 3119 O O     A HOH F 4 .   ? 25.31089  -22.47818 32.94891  0.607 12.27383  ? 1673 HOH A O     1 
HETATM 3120 O O     B HOH F 4 .   ? 25.03252  -21.04482 32.34879  0.393 22.52441  ? 1673 HOH A O     1 
HETATM 3121 O O     . HOH F 4 .   ? 38.19124  -32.12079 21.99596  1.000 25.91562  ? 1674 HOH A O     1 
HETATM 3122 O O     . HOH F 4 .   ? 26.05302  -6.57053  21.03712  1.000 45.21350  ? 1675 HOH A O     1 
HETATM 3123 O O     . HOH F 4 .   ? 4.36932   -11.38745 2.28569   1.000 38.98265  ? 1676 HOH A O     1 
HETATM 3124 O O     . HOH F 4 .   ? 28.27457  -27.87275 20.23596  1.000 10.41820  ? 1677 HOH A O     1 
HETATM 3125 O O     . HOH F 4 .   ? 15.12919  -36.54970 18.77775  1.000 17.86801  ? 1678 HOH A O     1 
HETATM 3126 O O     . HOH F 4 .   ? 7.51768   -15.55861 10.77353  1.000 24.37910  ? 1679 HOH A O     1 
HETATM 3127 O O     . HOH F 4 .   ? 10.29790  -22.83058 38.98498  1.000 13.19447  ? 1680 HOH A O     1 
HETATM 3128 O O     . HOH F 4 .   ? 31.92501  -13.71213 -0.40752  1.000 19.31618  ? 1681 HOH A O     1 
HETATM 3129 O O     . HOH F 4 .   ? -4.15371  -25.17069 25.04613  1.000 42.06525  ? 1682 HOH A O     1 
HETATM 3130 O O     . HOH F 4 .   ? 33.37800  -14.29067 28.33041  1.000 31.52827  ? 1683 HOH A O     1 
HETATM 3131 O O     . HOH F 4 .   ? 20.04539  -14.38754 27.22150  1.000 17.47547  ? 1684 HOH A O     1 
HETATM 3132 O O     . HOH F 4 .   ? 22.83359  -18.95767 32.30063  1.000 38.09260  ? 1685 HOH A O     1 
HETATM 3133 O O     . HOH F 4 .   ? -2.53741  -21.34485 27.07142  1.000 23.55823  ? 1686 HOH A O     1 
HETATM 3134 O O     . HOH F 4 .   ? 16.56221  -10.76027 -21.41302 1.000 18.27824  ? 1687 HOH A O     1 
HETATM 3135 O O     . HOH F 4 .   ? 34.56275  -11.36455 12.63761  1.000 18.56004  ? 1688 HOH A O     1 
HETATM 3136 O O     . HOH F 4 .   ? 30.95479  -30.10628 26.95894  1.000 15.96463  ? 1689 HOH A O     1 
HETATM 3137 O O     . HOH F 4 .   ? 27.75278  0.07361   9.32423   1.000 14.09342  ? 1690 HOH A O     1 
HETATM 3138 O O     . HOH F 4 .   ? 27.99599  -29.13070 32.95183  1.000 31.37354  ? 1691 HOH A O     1 
HETATM 3139 O O     . HOH F 4 .   ? 29.88697  -29.52042 18.84118  1.000 15.24668  ? 1692 HOH A O     1 
HETATM 3140 O O     . HOH F 4 .   ? 19.28808  -40.63586 24.68616  1.000 33.35033  ? 1693 HOH A O     1 
HETATM 3141 O O     . HOH F 4 .   ? 24.97891  -8.29816  -12.72700 1.000 28.06861  ? 1694 HOH A O     1 
HETATM 3142 O O     . HOH F 4 .   ? 18.92355  -27.03413 10.34407  1.000 20.79457  ? 1695 HOH A O     1 
HETATM 3143 O O     A HOH F 4 .   ? 34.90907  -29.66267 13.06570  0.492 27.70630  ? 1696 HOH A O     1 
HETATM 3144 O O     B HOH F 4 .   ? 36.89417  -29.82234 13.81573  0.508 29.43456  ? 1696 HOH A O     1 
HETATM 3145 O O     . HOH F 4 .   ? 6.62219   -33.11344 29.19074  1.000 23.88797  ? 1697 HOH A O     1 
HETATM 3146 O O     . HOH F 4 .   ? 24.82315  0.26915   18.46770  1.000 31.72936  ? 1698 HOH A O     1 
HETATM 3147 O O     . HOH F 4 .   ? 3.81451   -31.13496 17.23805  1.000 30.46446  ? 1699 HOH A O     1 
HETATM 3148 O O     . HOH F 4 .   ? 7.68841   -31.46672 15.65942  1.000 49.66571  ? 1700 HOH A O     1 
HETATM 3149 O O     A HOH F 4 .   ? 31.95831  -29.21040 16.34654  0.508 16.08723  ? 1701 HOH A O     1 
HETATM 3150 O O     B HOH F 4 .   ? 32.47656  -28.44644 15.06683  0.492 22.84567  ? 1701 HOH A O     1 
HETATM 3151 O O     . HOH F 4 .   ? 18.56068  -22.52961 14.51028  1.000 13.95669  ? 1702 HOH A O     1 
HETATM 3152 O O     . HOH F 4 .   ? 3.01005   -34.67116 31.47781  1.000 20.78987  ? 1703 HOH A O     1 
HETATM 3153 O O     . HOH F 4 .   ? 20.76351  -41.17979 20.15727  1.000 58.24995  ? 1704 HOH A O     1 
HETATM 3154 O O     . HOH F 4 .   ? 16.36601  -23.24071 12.24226  1.000 39.16075  ? 1705 HOH A O     1 
HETATM 3155 O O     . HOH F 4 .   ? 28.09058  -10.91281 -9.73921  1.000 20.88575  ? 1706 HOH A O     1 
HETATM 3156 O O     . HOH F 4 .   ? 14.22017  0.00359   13.07347  1.000 28.73982  ? 1707 HOH A O     1 
HETATM 3157 O O     . HOH F 4 .   ? 31.40400  -21.58740 3.28053   1.000 15.85924  ? 1708 HOH A O     1 
HETATM 3158 O O     . HOH F 4 .   ? 5.45531   -20.60273 15.04043  1.000 17.10279  ? 1709 HOH A O     1 
HETATM 3159 O O     . HOH F 4 .   ? 19.26928  -23.36451 -14.29738 1.000 20.95626  ? 1710 HOH A O     1 
HETATM 3160 O O     . HOH F 4 .   ? 38.76983  -9.77287  19.50305  1.000 34.14473  ? 1711 HOH A O     1 
HETATM 3161 O O     . HOH F 4 .   ? 22.94745  -1.16064  19.47313  1.000 33.03367  ? 1712 HOH A O     1 
HETATM 3162 O O     . HOH F 4 .   ? -0.51453  -4.85863  21.38512  1.000 47.03092  ? 1713 HOH A O     1 
HETATM 3163 O O     . HOH F 4 .   ? 4.96751   -7.34189  -1.76094  1.000 30.43177  ? 1714 HOH A O     1 
HETATM 3164 O O     . HOH F 4 .   ? 17.47497  1.44626   0.98723   1.000 49.80571  ? 1715 HOH A O     1 
HETATM 3165 O O     . HOH F 4 .   ? 38.88670  -26.11981 19.55283  1.000 17.09881  ? 1716 HOH A O     1 
HETATM 3166 O O     . HOH F 4 .   ? 24.18704  -17.64391 22.11439  1.000 9.50982   ? 1717 HOH A O     1 
HETATM 3167 O O     . HOH F 4 .   ? 28.62809  -26.71126 3.81336   1.000 37.76849  ? 1718 HOH A O     1 
HETATM 3168 O O     . HOH F 4 .   ? -11.56510 -20.16421 14.38335  1.000 49.17329  ? 1719 HOH A O     1 
HETATM 3169 O O     . HOH F 4 .   ? 10.14670  0.30871   19.44043  1.000 50.27844  ? 1720 HOH A O     1 
HETATM 3170 O O     . HOH F 4 .   ? 16.47637  -36.49052 12.50181  1.000 32.69056  ? 1721 HOH A O     1 
HETATM 3171 O O     . HOH F 4 .   ? 4.88147   -22.94627 31.96159  1.000 11.24645  ? 1722 HOH A O     1 
HETATM 3172 O O     . HOH F 4 .   ? 6.71348   -33.79139 16.12393  1.000 43.98805  ? 1723 HOH A O     1 
HETATM 3173 O O     . HOH F 4 .   ? 35.87847  -15.81702 15.85643  1.000 11.23876  ? 1724 HOH A O     1 
HETATM 3174 O O     . HOH F 4 .   ? 17.58703  -34.11134 11.62291  1.000 19.47582  ? 1725 HOH A O     1 
HETATM 3175 O O     . HOH F 4 .   ? 35.49588  -12.13127 27.10968  1.000 22.93567  ? 1726 HOH A O     1 
HETATM 3176 O O     . HOH F 4 .   ? 26.80263  -27.02193 22.42631  1.000 9.77890   ? 1727 HOH A O     1 
HETATM 3177 O O     . HOH F 4 .   ? 36.89019  -8.22616  6.12402   1.000 35.79482  ? 1728 HOH A O     1 
HETATM 3178 O O     . HOH F 4 .   ? 37.74365  -22.05928 1.49646   1.000 43.02400  ? 1729 HOH A O     1 
HETATM 3179 O O     . HOH F 4 .   ? 21.63081  -21.37005 16.21613  1.000 12.44432  ? 1730 HOH A O     1 
HETATM 3180 O O     . HOH F 4 .   ? 18.19918  -34.15805 33.74292  1.000 24.30529  ? 1731 HOH A O     1 
HETATM 3181 O O     . HOH F 4 .   ? 17.14790  0.75486   15.58861  1.000 51.75828  ? 1732 HOH A O     1 
HETATM 3182 O O     . HOH F 4 .   ? 9.45969   -19.73048 -7.75274  1.000 30.94558  ? 1733 HOH A O     1 
HETATM 3183 O O     . HOH F 4 .   ? 19.86841  -39.55644 13.87436  1.000 43.47751  ? 1734 HOH A O     1 
HETATM 3184 O O     . HOH F 4 .   ? -3.16336  -7.81657  15.60866  1.000 40.45041  ? 1735 HOH A O     1 
HETATM 3185 O O     . HOH F 4 .   ? -21.62584 -9.77996  12.99945  1.000 48.43219  ? 1736 HOH A O     1 
HETATM 3186 O O     . HOH F 4 .   ? 26.05817  -25.35052 0.96110   1.000 28.44233  ? 1737 HOH A O     1 
HETATM 3187 O O     . HOH F 4 .   ? 21.49326  -15.94471 29.70337  1.000 35.36941  ? 1738 HOH A O     1 
HETATM 3188 O O     . HOH F 4 .   ? 17.26372  -36.00930 32.08236  1.000 16.17768  ? 1739 HOH A O     1 
HETATM 3189 O O     . HOH F 4 .   ? 4.10389   -22.01738 12.99773  1.000 20.30145  ? 1740 HOH A O     1 
HETATM 3190 O O     . HOH F 4 .   ? 11.60308  -14.43259 -13.84152 1.000 26.86251  ? 1741 HOH A O     1 
HETATM 3191 O O     . HOH F 4 .   ? 28.87445  -13.32652 -3.19213  1.000 17.66176  ? 1742 HOH A O     1 
HETATM 3192 O O     . HOH F 4 .   ? 17.87639  -22.07545 36.44339  1.000 34.99192  ? 1743 HOH A O     1 
HETATM 3193 O O     . HOH F 4 .   ? 17.05871  -4.96521  21.21795  1.000 18.23967  ? 1744 HOH A O     1 
HETATM 3194 O O     . HOH F 4 .   ? 26.63725  -6.73935  -5.11126  1.000 15.91386  ? 1745 HOH A O     1 
HETATM 3195 O O     . HOH F 4 .   ? -0.44469  -5.57418  1.65257   1.000 50.20775  ? 1746 HOH A O     1 
HETATM 3196 O O     . HOH F 4 .   ? 13.89456  -4.65256  -9.21990  1.000 33.94193  ? 1747 HOH A O     1 
HETATM 3197 O O     . HOH F 4 .   ? 5.94877   -14.39954 8.46108   1.000 39.97979  ? 1748 HOH A O     1 
HETATM 3198 O O     . HOH F 4 .   ? -1.16691  -15.39796 18.75556  1.000 35.69944  ? 1749 HOH A O     1 
HETATM 3199 O O     . HOH F 4 .   ? 29.63522  -17.24701 -0.60481  1.000 13.29078  ? 1750 HOH A O     1 
HETATM 3200 O O     . HOH F 4 .   ? 16.76391  -25.38091 1.52145   1.000 28.70753  ? 1751 HOH A O     1 
HETATM 3201 O O     . HOH F 4 .   ? 27.76361  -32.44930 30.44856  1.000 35.21966  ? 1752 HOH A O     1 
HETATM 3202 O O     . HOH F 4 .   ? 24.83523  -18.77360 -8.69846  1.000 27.60125  ? 1753 HOH A O     1 
HETATM 3203 O O     . HOH F 4 .   ? 30.46739  -21.62826 0.74203   1.000 19.80613  ? 1754 HOH A O     1 
HETATM 3204 O O     . HOH F 4 .   ? 2.37677   -19.12086 7.48167   1.000 21.93635  ? 1755 HOH A O     1 
HETATM 3205 O O     . HOH F 4 .   ? -3.02689  -30.65297 25.41148  1.000 18.25943  ? 1756 HOH A O     1 
HETATM 3206 O O     . HOH F 4 .   ? 38.95132  -18.94427 9.96637   1.000 16.05437  ? 1757 HOH A O     1 
HETATM 3207 O O     . HOH F 4 .   ? 4.97744   -26.22107 10.91218  1.000 40.04574  ? 1758 HOH A O     1 
HETATM 3208 O O     . HOH F 4 .   ? 26.75669  -21.72327 -11.20595 1.000 32.51518  ? 1759 HOH A O     1 
HETATM 3209 O O     . HOH F 4 .   ? 24.60787  -37.54657 16.77783  1.000 24.87678  ? 1760 HOH A O     1 
HETATM 3210 O O     . HOH F 4 .   ? 39.17248  -14.50045 28.81853  1.000 47.53281  ? 1761 HOH A O     1 
HETATM 3211 O O     . HOH F 4 .   ? 36.59653  -25.12705 12.11216  1.000 35.78051  ? 1762 HOH A O     1 
HETATM 3212 O O     . HOH F 4 .   ? 23.70743  -13.78535 -14.25040 1.000 46.52463  ? 1763 HOH A O     1 
HETATM 3213 O O     . HOH F 4 .   ? 36.91710  -6.04397  7.51119   1.000 48.49467  ? 1764 HOH A O     1 
HETATM 3214 O O     . HOH F 4 .   ? 24.81264  -2.51506  -7.81556  1.000 32.02678  ? 1765 HOH A O     1 
HETATM 3215 O O     . HOH F 4 .   ? 14.29466  -36.11876 14.44380  1.000 23.27537  ? 1766 HOH A O     1 
HETATM 3216 O O     . HOH F 4 .   ? 27.74190  -23.27612 -2.33359  1.000 28.63707  ? 1767 HOH A O     1 
HETATM 3217 O O     . HOH F 4 .   ? 18.04335  -5.27439  -10.52676 1.000 25.05909  ? 1768 HOH A O     1 
HETATM 3218 O O     . HOH F 4 .   ? -10.26833 -11.72452 16.07574  1.000 41.53326  ? 1769 HOH A O     1 
HETATM 3219 O O     . HOH F 4 .   ? 14.54222  -2.75276  -7.66701  1.000 60.92815  ? 1770 HOH A O     1 
HETATM 3220 O O     . HOH F 4 .   ? 5.86870   -0.15945  17.26959  1.000 23.79334  ? 1771 HOH A O     1 
HETATM 3221 O O     . HOH F 4 .   ? 38.10827  -23.57620 26.24285  1.000 10.17510  ? 1772 HOH A O     1 
HETATM 3222 O O     . HOH F 4 .   ? 6.53650   -36.37431 18.61177  1.000 28.41222  ? 1773 HOH A O     1 
HETATM 3223 O O     . HOH F 4 .   ? 16.16406  -0.78531  7.94104   1.000 22.30959  ? 1774 HOH A O     1 
HETATM 3224 O O     . HOH F 4 .   ? 3.81627   -10.32874 15.07252  1.000 49.13056  ? 1775 HOH A O     1 
HETATM 3225 O O     . HOH F 4 .   ? 14.75686  -5.54246  19.82708  1.000 14.95691  ? 1776 HOH A O     1 
HETATM 3226 O O     . HOH F 4 .   ? 11.92836  -1.61530  19.46822  1.000 48.48132  ? 1777 HOH A O     1 
HETATM 3227 O O     . HOH F 4 .   ? 26.97124  -27.01575 -8.98602  1.000 52.61038  ? 1778 HOH A O     1 
HETATM 3228 O O     . HOH F 4 .   ? -1.02930  -18.75270 28.58607  1.000 25.89162  ? 1779 HOH A O     1 
HETATM 3229 O O     . HOH F 4 .   ? 31.91860  -8.40210  20.95926  1.000 56.07985  ? 1780 HOH A O     1 
HETATM 3230 O O     . HOH F 4 .   ? 19.49651  -0.48711  12.54420  1.000 28.77364  ? 1781 HOH A O     1 
HETATM 3231 O O     . HOH F 4 .   ? 6.18181   -9.32513  13.93062  1.000 21.19352  ? 1782 HOH A O     1 
HETATM 3232 O O     . HOH F 4 .   ? 21.65900  -17.63212 -12.73096 1.000 44.83542  ? 1783 HOH A O     1 
HETATM 3233 O O     . HOH F 4 .   ? 0.49848   -12.93017 22.80865  1.000 38.49508  ? 1784 HOH A O     1 
HETATM 3234 O O     . HOH F 4 .   ? 19.41568  -27.41814 -2.86846  1.000 34.83227  ? 1785 HOH A O     1 
HETATM 3235 O O     . HOH F 4 .   ? 1.22369   -16.11277 2.29118   1.000 50.22198  ? 1786 HOH A O     1 
HETATM 3236 O O     . HOH F 4 .   ? 9.18816   -17.96263 -11.31413 1.000 60.64814  ? 1787 HOH A O     1 
HETATM 3237 O O     . HOH F 4 .   ? 23.08607  -2.05478  6.43184   1.000 16.22809  ? 1788 HOH A O     1 
HETATM 3238 O O     . HOH F 4 .   ? 10.94096  -25.52719 5.32327   1.000 23.45650  ? 1789 HOH A O     1 
HETATM 3239 O O     . HOH F 4 .   ? 17.08113  -39.37913 29.08565  1.000 26.53336  ? 1790 HOH A O     1 
HETATM 3240 O O     . HOH F 4 .   ? 10.77976  -17.42760 -13.76974 1.000 27.76128  ? 1791 HOH A O     1 
HETATM 3241 O O     . HOH F 4 .   ? -1.23562  -2.12261  8.45533   1.000 55.82943  ? 1792 HOH A O     1 
HETATM 3242 O O     . HOH F 4 .   ? 27.85476  -34.13670 25.95077  1.000 46.75864  ? 1793 HOH A O     1 
HETATM 3243 O O     . HOH F 4 .   ? 13.36335  -14.89058 33.64899  1.000 17.12437  ? 1794 HOH A O     1 
HETATM 3244 O O     . HOH F 4 .   ? 41.00522  -15.76205 4.81527   1.000 51.02795  ? 1795 HOH A O     1 
HETATM 3245 O O     . HOH F 4 .   ? -19.98325 -9.88968  16.79610  1.000 45.45110  ? 1796 HOH A O     1 
HETATM 3246 O O     . HOH F 4 .   ? 32.61145  -13.83461 -5.39678  1.000 48.04977  ? 1797 HOH A O     1 
HETATM 3247 O O     . HOH F 4 .   ? 22.49089  -16.51775 33.63408  1.000 44.06970  ? 1798 HOH A O     1 
HETATM 3248 O O     . HOH F 4 .   ? 12.22922  -28.35749 8.33371   1.000 45.69153  ? 1799 HOH A O     1 
HETATM 3249 O O     . HOH F 4 .   ? 8.98041   -20.95504 -1.96172  1.000 18.05520  ? 1800 HOH A O     1 
HETATM 3250 O O     . HOH F 4 .   ? 2.68188   -6.27367  -0.27031  1.000 72.98273  ? 1801 HOH A O     1 
HETATM 3251 O O     . HOH F 4 .   ? 32.35053  -17.27780 -3.87796  1.000 49.26285  ? 1802 HOH A O     1 
HETATM 3252 O O     . HOH F 4 .   ? 9.90558   -6.36388  26.68771  1.000 40.54846  ? 1803 HOH A O     1 
HETATM 3253 O O     . HOH F 4 .   ? 31.42317  -27.05475 13.63814  1.000 26.87652  ? 1804 HOH A O     1 
HETATM 3254 O O     . HOH F 4 .   ? 16.73082  -25.69453 -0.99252  1.000 42.53811  ? 1805 HOH A O     1 
HETATM 3255 O O     . HOH F 4 .   ? 10.31825  -26.87191 8.54398   1.000 38.02114  ? 1806 HOH A O     1 
HETATM 3256 O O     . HOH F 4 .   ? 23.42772  -18.33255 34.72725  1.000 50.96672  ? 1807 HOH A O     1 
HETATM 3257 O O     . HOH F 4 .   ? 32.98199  -8.22737  18.66794  1.000 36.74757  ? 1808 HOH A O     1 
HETATM 3258 O O     . HOH F 4 .   ? 20.37108  -25.54169 -13.05364 1.000 21.64868  ? 1809 HOH A O     1 
HETATM 3259 O O     . HOH F 4 .   ? -1.44039  -12.60655 20.33719  1.000 46.60710  ? 1810 HOH A O     1 
HETATM 3260 O O     . HOH F 4 .   ? -6.68047  -16.69083 16.37962  1.000 40.41548  ? 1811 HOH A O     1 
HETATM 3261 O O     . HOH F 4 .   ? 20.53866  -0.06413  6.04251   1.000 32.14266  ? 1812 HOH A O     1 
HETATM 3262 O O     . HOH F 4 .   ? 8.69431   -14.61319 32.93687  1.000 23.43471  ? 1813 HOH A O     1 
HETATM 3263 O O     . HOH F 4 .   ? 1.10068   -22.93506 29.66533  1.000 16.12124  ? 1814 HOH A O     1 
HETATM 3264 O O     . HOH F 4 .   ? 27.21538  -5.50692  -2.74505  1.000 31.82617  ? 1815 HOH A O     1 
HETATM 3265 O O     . HOH F 4 .   ? 35.11860  -12.16580 0.58636   1.000 50.75574  ? 1816 HOH A O     1 
HETATM 3266 O O     . HOH F 4 .   ? 27.877    -27.184   35.878    1.000 60.81017  ? 1817 HOH A O     1 
HETATM 3267 O O     . HOH F 4 .   ? 6.27273   -21.84369 1.93458   1.000 38.64389  ? 1818 HOH A O     1 
HETATM 3268 O O     . HOH F 4 .   ? 29.78231  -32.23035 8.68357   1.000 47.76945  ? 1819 HOH A O     1 
HETATM 3269 O O     . HOH F 4 .   ? 36.86725  -10.79866 2.12037   1.000 57.42785  ? 1820 HOH A O     1 
HETATM 3270 O O     . HOH F 4 .   ? -5.54129  -27.67944 25.05895  1.000 43.19505  ? 1821 HOH A O     1 
HETATM 3271 O O     . HOH F 4 .   ? 25.713    -31.706   33.475    1.000 54.53776  ? 1822 HOH A O     1 
HETATM 3272 O O     . HOH F 4 .   ? -3.41789  -21.47744 14.21534  1.000 44.34156  ? 1823 HOH A O     1 
HETATM 3273 O O     . HOH F 4 .   ? -3.44184  -9.50762  17.80237  1.000 46.59532  ? 1824 HOH A O     1 
HETATM 3274 O O     . HOH F 4 .   ? 21.95748  -13.03663 25.63930  1.000 17.87029  ? 1825 HOH A O     1 
HETATM 3275 O O     . HOH F 4 .   ? 28.10203  -14.55557 30.69371  1.000 42.41881  ? 1826 HOH A O     1 
HETATM 3276 O O     . HOH F 4 .   ? 27.06912  -37.01017 16.08305  1.000 44.79846  ? 1827 HOH A O     1 
HETATM 3277 O O     . HOH F 4 .   ? 12.67441  -10.14792 -19.49622 1.000 47.26854  ? 1828 HOH A O     1 
HETATM 3278 O O     . HOH F 4 .   ? 19.19473  -6.91852  21.44950  1.000 18.97294  ? 1829 HOH A O     1 
HETATM 3279 O O     . HOH F 4 .   ? 15.23225  -37.48509 32.77546  1.000 45.35370  ? 1830 HOH A O     1 
HETATM 3280 O O     . HOH F 4 .   ? 37.21373  -12.25851 11.91367  1.000 49.18886  ? 1831 HOH A O     1 
HETATM 3281 O O     . HOH F 4 .   ? 20.89463  -29.87884 -5.12376  1.000 41.60027  ? 1832 HOH A O     1 
HETATM 3282 O O     . HOH F 4 .   ? 22.47569  -40.21803 18.24860  1.000 56.13740  ? 1833 HOH A O     1 
HETATM 3283 O O     . HOH F 4 .   ? 20.71451  -30.11531 -13.68525 1.000 57.29136  ? 1834 HOH A O     1 
HETATM 3284 O O     . HOH F 4 .   ? 16.92039  -1.60659  -6.56951  1.000 38.77474  ? 1835 HOH A O     1 
HETATM 3285 O O     . HOH F 4 .   ? 2.09824   -4.52333  -2.65874  1.000 40.99880  ? 1836 HOH A O     1 
HETATM 3286 O O     . HOH F 4 .   ? 27.86660  -21.54810 -6.10065  1.000 37.80026  ? 1837 HOH A O     1 
HETATM 3287 O O     . HOH F 4 .   ? 36.55897  -8.20825  10.02880  1.000 42.70415  ? 1838 HOH A O     1 
HETATM 3288 O O     . HOH F 4 .   ? 4.64216   -15.63134 33.17078  1.000 37.00968  ? 1839 HOH A O     1 
HETATM 3289 O O     A HOH F 4 .   ? 14.72157  -28.73026 12.08628  0.553 15.92189  ? 1840 HOH A O     1 
HETATM 3290 O O     B HOH F 4 .   ? 15.71170  -28.05689 12.29296  0.447 19.26076  ? 1840 HOH A O     1 
HETATM 3291 O O     . HOH F 4 .   ? 1.32947   -31.84828 17.37492  1.000 35.86611  ? 1841 HOH A O     1 
HETATM 3292 O O     . HOH F 4 .   ? 25.64691  -13.56107 30.02080  1.000 52.75954  ? 1842 HOH A O     1 
HETATM 3293 O O     . HOH F 4 .   ? 22.81319  -0.02611  2.68955   1.000 29.08774  ? 1843 HOH A O     1 
HETATM 3294 O O     . HOH F 4 .   ? 30.86511  -26.08594 11.11208  1.000 23.50839  ? 1844 HOH A O     1 
HETATM 3295 O O     . HOH F 4 .   ? 13.99113  1.18974   10.85486  1.000 56.86034  ? 1845 HOH A O     1 
HETATM 3296 O O     . HOH F 4 .   ? 7.84376   -30.45948 31.52192  1.000 33.52580  ? 1846 HOH A O     1 
HETATM 3297 O O     . HOH F 4 .   ? 6.38298   -19.99290 -1.76139  1.000 22.37879  ? 1847 HOH A O     1 
HETATM 3298 O O     . HOH F 4 .   ? 15.66247  -21.49972 39.59353  1.000 47.52884  ? 1848 HOH A O     1 
HETATM 3299 O O     . HOH F 4 .   ? 13.96661  2.00785   6.70297   1.000 54.07235  ? 1849 HOH A O     1 
HETATM 3300 O O     . HOH F 4 .   ? 7.98748   -14.55928 38.32006  1.000 46.66762  ? 1850 HOH A O     1 
HETATM 3301 O O     . HOH F 4 .   ? 11.45474  -4.63337  23.10621  1.000 34.16627  ? 1851 HOH A O     1 
HETATM 3302 O O     . HOH F 4 .   ? -1.22363  -18.09530 16.36938  1.000 39.95099  ? 1852 HOH A O     1 
HETATM 3303 O O     . HOH F 4 .   ? 3.95216   -14.66700 31.12905  1.000 45.70686  ? 1853 HOH A O     1 
HETATM 3304 O O     . HOH F 4 .   ? -0.72175  -37.58928 17.46169  1.000 47.44672  ? 1854 HOH A O     1 
HETATM 3305 O O     . HOH F 4 .   ? 30.03320  -27.67799 28.36410  1.000 29.19855  ? 1855 HOH A O     1 
HETATM 3306 O O     . HOH F 4 .   ? 39.77633  -17.55271 28.69706  1.000 51.72293  ? 1856 HOH A O     1 
HETATM 3307 O O     . HOH F 4 .   ? 6.38063   -12.17428 30.41567  1.000 50.08832  ? 1857 HOH A O     1 
HETATM 3308 O O     . HOH F 4 .   ? 27.19251  -0.38098  19.90610  1.000 39.62912  ? 1858 HOH A O     1 
HETATM 3309 O O     . HOH F 4 .   ? 5.45769   -5.07361  26.38778  1.000 43.73530  ? 1859 HOH A O     1 
HETATM 3310 O O     A HOH F 4 .   ? 22.32435  -10.42323 25.53011  0.542 29.24059  ? 1860 HOH A O     1 
HETATM 3311 O O     B HOH F 4 .   ? 23.64079  -10.00869 25.46233  0.458 25.61576  ? 1860 HOH A O     1 
HETATM 3312 O O     . HOH F 4 .   ? 3.79867   -15.05102 6.94176   1.000 32.57287  ? 1861 HOH A O     1 
HETATM 3313 O O     . HOH F 4 .   ? 21.56515  0.20713   8.13103   1.000 54.67841  ? 1862 HOH A O     1 
HETATM 3314 O O     . HOH F 4 .   ? 4.49842   -9.64605  17.23391  1.000 45.97520  ? 1863 HOH A O     1 
HETATM 3315 O O     . HOH F 4 .   ? 16.16416  1.66160   11.47904  1.000 44.90312  ? 1864 HOH A O     1 
HETATM 3316 O O     . HOH F 4 .   ? 8.46603   -12.87033 30.63283  1.000 49.49686  ? 1865 HOH A O     1 
HETATM 3317 O O     . HOH F 4 .   ? 40.08332  -17.10657 8.17460   1.000 37.18885  ? 1866 HOH A O     1 
HETATM 3318 O O     . HOH F 4 .   ? 35.86044  -18.46229 29.48714  1.000 34.21667  ? 1867 HOH A O     1 
HETATM 3319 O O     . HOH F 4 .   ? 30.50405  -15.22627 -2.16936  1.000 18.26264  ? 1868 HOH A O     1 
HETATM 3320 O O     . HOH F 4 .   ? 16.64963  -1.56215  -9.62470  1.000 54.24925  ? 1869 HOH A O     1 
HETATM 3321 O O     . HOH F 4 .   ? 15.41709  -5.33258  -11.28908 1.000 48.53751  ? 1870 HOH A O     1 
HETATM 3322 O O     . HOH F 4 .   ? 29.74271  -10.59136 -5.94569  1.000 41.02375  ? 1871 HOH A O     1 
HETATM 3323 O O     . HOH F 4 .   ? 23.07661  -5.45728  -14.40505 1.000 30.57008  ? 1872 HOH A O     1 
HETATM 3324 O O     . HOH F 4 .   ? 10.81931  -15.35002 34.41506  1.000 19.74264  ? 1873 HOH A O     1 
HETATM 3325 O O     . HOH F 4 .   ? 38.45803  -21.23956 8.58350   1.000 31.60216  ? 1874 HOH A O     1 
HETATM 3326 O O     . HOH F 4 .   ? 4.11050   -29.24414 15.91228  1.000 25.56342  ? 1875 HOH A O     1 
HETATM 3327 O O     . HOH F 4 .   ? 22.01597  -26.97630 0.69033   1.000 28.40849  ? 1876 HOH A O     1 
HETATM 3328 O O     . HOH F 4 .   ? 21.41469  -6.40665  22.96140  1.000 34.41115  ? 1877 HOH A O     1 
HETATM 3329 O O     . HOH F 4 .   ? 28.19490  -27.50231 7.97176   1.000 18.90525  ? 1878 HOH A O     1 
HETATM 3330 O O     . HOH F 4 .   ? 21.21943  1.65177   4.59162   1.000 45.66618  ? 1879 HOH A O     1 
HETATM 3331 O O     . HOH F 4 .   ? 27.94489  -19.40331 -8.08698  1.000 45.64955  ? 1880 HOH A O     1 
HETATM 3332 O O     . HOH F 4 .   ? 1.19189   -38.84907 29.46677  1.000 42.78423  ? 1881 HOH A O     1 
HETATM 3333 O O     . HOH F 4 .   ? 40.64460  -17.14556 25.95338  1.000 36.98720  ? 1882 HOH A O     1 
HETATM 3334 O O     . HOH F 4 .   ? 30.90247  -18.89871 -7.34593  1.000 50.05533  ? 1883 HOH A O     1 
HETATM 3335 O O     . HOH F 4 .   ? 13.54627  -13.44756 -19.35701 1.000 55.19762  ? 1884 HOH A O     1 
HETATM 3336 O O     . HOH F 4 .   ? 19.04369  -29.19014 -7.55556  1.000 32.54411  ? 1885 HOH A O     1 
HETATM 3337 O O     . HOH F 4 .   ? 12.41179  -0.96087  -4.59719  1.000 35.95988  ? 1886 HOH A O     1 
HETATM 3338 O O     . HOH F 4 .   ? 42.72446  -22.26194 15.07121  1.000 40.69256  ? 1887 HOH A O     1 
HETATM 3339 O O     . HOH F 4 .   ? 34.30522  -33.86160 20.22401  1.000 52.83638  ? 1888 HOH A O     1 
HETATM 3340 O O     . HOH F 4 .   ? 19.68560  -41.59641 16.94489  1.000 50.03841  ? 1889 HOH A O     1 
HETATM 3341 O O     . HOH F 4 .   ? 1.08196   -19.00561 33.47526  1.000 33.81835  ? 1890 HOH A O     1 
HETATM 3342 O O     . HOH F 4 .   ? 6.25141   -11.44817 5.43453   1.000 34.08050  ? 1891 HOH A O     1 
HETATM 3343 O O     . HOH F 4 .   ? 38.79727  -27.53620 15.04739  1.000 36.27321  ? 1892 HOH A O     1 
HETATM 3344 O O     . HOH F 4 .   ? 6.00834   -6.92898  -6.06584  1.000 44.89635  ? 1893 HOH A O     1 
HETATM 3345 O O     . HOH F 4 .   ? 1.01974   -36.70412 31.40137  1.000 43.06952  ? 1894 HOH A O     1 
HETATM 3346 O O     . HOH F 4 .   ? 4.11341   -12.63588 5.22533   1.000 52.14598  ? 1895 HOH A O     1 
HETATM 3347 O O     . HOH F 4 .   ? 4.80962   -35.96234 16.04268  1.000 50.88427  ? 1896 HOH A O     1 
HETATM 3348 O O     . HOH F 4 .   ? 26.77601  -26.61525 5.69787   1.000 27.44800  ? 1897 HOH A O     1 
HETATM 3349 O O     . HOH F 4 .   ? 8.03187   -17.37458 -9.27509  1.000 49.55955  ? 1898 HOH A O     1 
HETATM 3350 O O     . HOH F 4 .   ? 26.12908  -34.91070 21.48506  1.000 25.01649  ? 1899 HOH A O     1 
HETATM 3351 O O     . HOH F 4 .   ? 0.72076   -20.09844 5.44174   1.000 32.02741  ? 1900 HOH A O     1 
HETATM 3352 O O     . HOH F 4 .   ? 1.81066   -10.51376 13.49697  1.000 46.57359  ? 1901 HOH A O     1 
HETATM 3353 O O     . HOH F 4 .   ? 4.88114   -21.43226 -0.26486  1.000 33.83632  ? 1902 HOH A O     1 
HETATM 3354 O O     . HOH F 4 .   ? 24.35542  -26.69306 4.45485   1.000 23.72022  ? 1903 HOH A O     1 
HETATM 3355 O O     . HOH F 4 .   ? 1.54998   -14.13280 -0.32812  1.000 44.66211  ? 1904 HOH A O     1 
HETATM 3356 O O     . HOH F 4 .   ? 5.74663   -27.70431 9.09797   1.000 57.85088  ? 1905 HOH A O     1 
HETATM 3357 O O     . HOH F 4 .   ? 4.30902   -5.20318  -4.31657  1.000 51.25182  ? 1906 HOH A O     1 
HETATM 3358 O O     . HOH F 4 .   ? 2.87245   -21.19118 -3.57019  1.000 45.68787  ? 1907 HOH A O     1 
HETATM 3359 O O     . HOH F 4 .   ? 30.26931  -12.77714 -10.07297 1.000 51.82230  ? 1908 HOH A O     1 
HETATM 3360 O O     . HOH F 4 .   ? 26.48055  -32.10507 8.15584   1.000 51.05292  ? 1909 HOH A O     1 
HETATM 3361 O O     . HOH F 4 .   ? 36.47152  -13.97281 -0.68061  1.000 49.58403  ? 1910 HOH A O     1 
HETATM 3362 O O     . HOH F 4 .   ? 39.02533  -12.28016 9.05069   1.000 53.16799  ? 1911 HOH A O     1 
HETATM 3363 O O     . HOH F 4 .   ? -4.14231  -28.72222 17.60697  1.000 43.80430  ? 1912 HOH A O     1 
HETATM 3364 O O     . HOH F 4 .   ? -5.19815  -19.09115 15.97563  1.000 41.68744  ? 1913 HOH A O     1 
HETATM 3365 O O     . HOH F 4 .   ? 21.96737  -11.64657 -17.19498 1.000 65.10714  ? 1914 HOH A O     1 
HETATM 3366 O O     . HOH F 4 .   ? 17.84456  -27.31364 1.45642   1.000 63.79711  ? 1915 HOH A O     1 
HETATM 3367 O O     . HOH F 4 .   ? 15.51878  -14.61124 35.45601  1.000 35.09440  ? 1916 HOH A O     1 
HETATM 3368 O O     . HOH F 4 .   ? 24.11374  -38.63335 13.36729  1.000 53.87592  ? 1917 HOH A O     1 
HETATM 3369 O O     . HOH F 4 .   ? 18.81165  -40.91485 27.41207  1.000 39.62975  ? 1918 HOH A O     1 
HETATM 3370 O O     . HOH F 4 .   ? 39.46448  -18.92040 24.48325  1.000 30.17481  ? 1919 HOH A O     1 
HETATM 3371 O O     . HOH F 4 .   ? 22.33933  -36.94138 32.27490  1.000 53.05599  ? 1920 HOH A O     1 
HETATM 3372 O O     . HOH F 4 .   ? 2.99144   -20.03443 16.35598  1.000 24.69477  ? 1921 HOH A O     1 
HETATM 3373 O O     . HOH F 4 .   ? 39.19210  -27.62186 17.26621  1.000 61.36784  ? 1922 HOH A O     1 
HETATM 3374 O O     . HOH F 4 .   ? 33.20666  -10.54773 0.72968   1.000 50.32816  ? 1923 HOH A O     1 
HETATM 3375 O O     . HOH F 4 .   ? 18.49449  -38.08408 30.93890  1.000 25.98995  ? 1924 HOH A O     1 
HETATM 3376 O O     . HOH F 4 .   ? 38.05475  -9.53837  8.72375   1.000 56.13793  ? 1925 HOH A O     1 
HETATM 3377 O O     . HOH F 4 .   ? 13.55942  -23.10856 41.53353  1.000 45.62400  ? 1926 HOH A O     1 
HETATM 3378 O O     . HOH F 4 .   ? 19.02835  -27.86814 -12.30177 1.000 24.81532  ? 1927 HOH A O     1 
HETATM 3379 O O     . HOH F 4 .   ? 1.32859   -27.03850 28.97067  1.000 12.25971  ? 1928 HOH A O     1 
HETATM 3380 O O     . HOH F 4 .   ? 11.25210  -24.29814 41.07767  1.000 28.01653  ? 1929 HOH A O     1 
HETATM 3381 O O     . HOH F 4 .   ? 26.71645  -35.65481 23.92084  1.000 47.46758  ? 1930 HOH A O     1 
HETATM 3382 O O     . HOH F 4 .   ? 14.95528  -7.35362  23.85147  1.000 23.82910  ? 1931 HOH A O     1 
HETATM 3383 O O     . HOH F 4 .   ? 0.94238   -26.61328 14.06636  1.000 37.96371  ? 1932 HOH A O     1 
HETATM 3384 O O     . HOH F 4 .   ? -2.63160  -28.60976 27.14714  1.000 17.62884  ? 1933 HOH A O     1 
HETATM 3385 O O     . HOH F 4 .   ? 36.18271  -35.29267 18.74337  1.000 50.61975  ? 1934 HOH A O     1 
HETATM 3386 O O     . HOH F 4 .   ? 1.42142   -19.67949 2.47817   1.000 44.68669  ? 1935 HOH A O     1 
HETATM 3387 O O     . HOH F 4 .   ? 25.64750  -8.74246  24.69693  1.000 44.14418  ? 1936 HOH A O     1 
HETATM 3388 O O     . HOH F 4 .   ? 39.48816  -19.42887 2.02012   1.000 51.37225  ? 1937 HOH A O     1 
HETATM 3389 O O     . HOH F 4 .   ? 24.47642  -27.19396 1.79318   1.000 25.38803  ? 1938 HOH A O     1 
HETATM 3390 O O     . HOH F 4 .   ? 31.49941  -20.20359 -2.92653  1.000 39.54768  ? 1939 HOH A O     1 
HETATM 3391 O O     . HOH F 4 .   ? 3.76343   -33.42973 15.08871  1.000 50.13386  ? 1940 HOH A O     1 
HETATM 3392 O O     . HOH F 4 .   ? 43.212    -17.224   12.137    1.000 43.32466  ? 1941 HOH A O     1 
HETATM 3393 O O     . HOH F 4 .   ? 35.15820  -22.93520 -0.36877  1.000 45.50039  ? 1942 HOH A O     1 
HETATM 3394 O O     . HOH F 4 .   ? 27.446    -10.891   -13.746   1.000 53.20639  ? 1943 HOH A O     1 
HETATM 3395 O O     . HOH F 4 .   ? 23.04787  -21.12214 33.51552  1.000 29.99273  ? 1944 HOH A O     1 
HETATM 3396 O O     . HOH F 4 .   ? 1.64781   -17.45784 16.25889  1.000 31.21004  ? 1945 HOH A O     1 
HETATM 3397 O O     . HOH F 4 .   ? 17.94838  0.65428   9.50617   1.000 40.44212  ? 1946 HOH A O     1 
HETATM 3398 O O     . HOH F 4 .   ? 20.68236  -32.07279 -12.53488 1.000 56.33619  ? 1947 HOH A O     1 
HETATM 3399 O O     . HOH F 4 .   ? 37.26321  -5.77712  11.04101  1.000 41.87131  ? 1948 HOH A O     1 
HETATM 3400 O O     . HOH F 4 .   ? 30.72972  -11.48528 -3.65538  1.000 31.96057  ? 1949 HOH A O     1 
HETATM 3401 O O     . HOH F 4 .   ? -5.07651  -29.62997 23.83145  1.000 32.87848  ? 1950 HOH A O     1 
HETATM 3402 O O     . HOH F 4 .   ? 31.83221  -27.02757 9.34893   1.000 42.98862  ? 1951 HOH A O     1 
HETATM 3403 O O     . HOH F 4 .   ? 13.56261  -3.10164  19.92740  1.000 31.04108  ? 1952 HOH A O     1 
HETATM 3404 O O     . HOH F 4 .   ? 28.88899  -7.96568  -6.07540  1.000 22.34011  ? 1953 HOH A O     1 
HETATM 3405 O O     . HOH F 4 .   ? 24.91193  -31.41092 5.73818   1.000 53.45434  ? 1954 HOH A O     1 
HETATM 3406 O O     . HOH F 4 .   ? 25.51578  -29.85650 1.53060   1.000 46.79106  ? 1955 HOH A O     1 
HETATM 3407 O O     . HOH F 4 .   ? 3.04161   2.18344   23.45258  1.000 41.30889  ? 1956 HOH A O     1 
HETATM 3408 O O     . HOH F 4 .   ? -3.75015  -29.74527 21.92781  1.000 40.49521  ? 1957 HOH A O     1 
HETATM 3409 O O     . HOH F 4 .   ? 24.612    3.627     -1.819    1.000 48.53244  ? 1958 HOH A O     1 
HETATM 3410 O O     . HOH F 4 .   ? 5.61972   -35.90580 28.88703  1.000 35.19074  ? 1959 HOH A O     1 
HETATM 3411 O O     . HOH F 4 .   ? 29.10272  -5.74997  -1.25363  1.000 45.10656  ? 1960 HOH A O     1 
HETATM 3412 O O     A HOH F 4 .   ? 8.62966   -32.14831 34.06459  0.553 29.44731  ? 1961 HOH A O     1 
HETATM 3413 O O     B HOH F 4 .   ? 8.55993   -30.91399 33.58015  0.447 31.76442  ? 1961 HOH A O     1 
HETATM 3414 O O     . HOH F 4 .   ? 37.77015  -25.04635 7.22621   1.000 58.23493  ? 1962 HOH A O     1 
HETATM 3415 O O     . HOH F 4 .   ? 25.91566  -10.87694 26.79921  1.000 32.76937  ? 1963 HOH A O     1 
HETATM 3416 O O     . HOH F 4 .   ? 33.06393  -25.63150 -0.06435  1.000 52.26518  ? 1964 HOH A O     1 
HETATM 3417 O O     . HOH F 4 .   ? 9.59036   -22.69115 0.41232   1.000 35.79194  ? 1965 HOH A O     1 
HETATM 3418 O O     . HOH F 4 .   ? 20.22575  -0.01451  19.62515  1.000 39.51114  ? 1966 HOH A O     1 
HETATM 3419 O O     . HOH F 4 .   ? 1.56610   -16.41954 8.05727   1.000 46.88005  ? 1967 HOH A O     1 
HETATM 3420 O O     . HOH F 4 .   ? 1.62160   -20.70299 11.92319  1.000 42.39638  ? 1968 HOH A O     1 
HETATM 3421 O O     . HOH F 4 .   ? 31.20246  -11.39532 -7.83378  1.000 40.00553  ? 1969 HOH A O     1 
HETATM 3422 O O     . HOH F 4 .   ? 20.02664  -16.35756 36.18118  1.000 45.35735  ? 1970 HOH A O     1 
HETATM 3423 O O     . HOH F 4 .   ? 43.13948  -17.63997 21.37872  1.000 47.25685  ? 1971 HOH A O     1 
HETATM 3424 O O     . HOH F 4 .   ? 19.85610  -15.19617 33.93008  1.000 42.57666  ? 1972 HOH A O     1 
HETATM 3425 O O     . HOH F 4 .   ? 19.05444  -34.83361 9.42030   1.000 46.76286  ? 1973 HOH A O     1 
HETATM 3426 O O     . HOH F 4 .   ? 36.80012  -34.04848 22.50939  1.000 52.63826  ? 1974 HOH A O     1 
HETATM 3427 O O     . HOH F 4 .   ? 30.20763  -31.61114 20.65680  1.000 26.68418  ? 1975 HOH A O     1 
HETATM 3428 O O     . HOH F 4 .   ? 24.37815  -39.74249 20.95085  1.000 60.27122  ? 1976 HOH A O     1 
HETATM 3429 O O     . HOH F 4 .   ? 10.85993  -14.76856 37.47072  1.000 42.89200  ? 1977 HOH A O     1 
HETATM 3430 O O     . HOH F 4 .   ? 5.23789   -19.60775 -4.27842  1.000 29.13631  ? 1978 HOH A O     1 
HETATM 3431 O O     . HOH F 4 .   ? 33.01539  -12.57804 -2.62535  1.000 61.35343  ? 1979 HOH A O     1 
HETATM 3432 O O     . HOH F 4 .   ? 39.81961  -21.48498 6.30979   1.000 39.29441  ? 1980 HOH A O     1 
HETATM 3433 O O     . HOH F 4 .   ? 30.07924  -31.91799 23.62958  1.000 29.68350  ? 1981 HOH A O     1 
HETATM 3434 O O     . HOH F 4 .   ? 13.81063  -44.08902 22.26386  1.000 44.79414  ? 1982 HOH A O     1 
HETATM 3435 O O     . HOH F 4 .   ? 2.28173   -23.96651 31.90139  1.000 16.23936  ? 1983 HOH A O     1 
HETATM 3436 O O     . HOH F 4 .   ? 12.30493  -16.48889 39.48385  1.000 36.66629  ? 1984 HOH A O     1 
HETATM 3437 O O     . HOH F 4 .   ? 11.75057  -34.78281 16.77812  1.000 25.85330  ? 1985 HOH A O     1 
HETATM 3438 O O     . HOH F 4 .   ? 31.30215  -23.65516 -0.63895  1.000 57.48292  ? 1986 HOH A O     1 
HETATM 3439 O O     . HOH F 4 .   ? 22.80530  -31.83338 -8.34717  1.000 56.46530  ? 1987 HOH A O     1 
HETATM 3440 O O     . HOH F 4 .   ? 28.66488  -33.72852 19.57611  1.000 49.54664  ? 1988 HOH A O     1 
HETATM 3441 O O     . HOH F 4 .   ? 13.52030  -33.66651 37.18419  1.000 49.23408  ? 1989 HOH A O     1 
HETATM 3442 O O     . HOH F 4 .   ? 9.43585   -34.26037 15.45144  1.000 32.39616  ? 1990 HOH A O     1 
HETATM 3443 O O     . HOH F 4 .   ? 12.57753  -30.04367 6.33036   1.000 28.41955  ? 1991 HOH A O     1 
HETATM 3444 O O     . HOH F 4 .   ? 7.37649   -30.18297 13.34017  1.000 34.74772  ? 1992 HOH A O     1 
HETATM 3445 O O     . HOH F 4 .   ? 18.67109  -8.99007  23.26560  1.000 37.38564  ? 1993 HOH A O     1 
HETATM 3446 O O     . HOH F 4 .   ? -6.46355  -30.46710 21.25438  1.000 49.88058  ? 1994 HOH A O     1 
HETATM 3447 O O     . HOH F 4 .   ? 28.58480  -30.22841 8.22929   1.000 40.34296  ? 1995 HOH A O     1 
HETATM 3448 O O     . HOH F 4 .   ? 29.06593  -8.46854  -10.52310 1.000 27.58506  ? 1996 HOH A O     1 
HETATM 3449 O O     . HOH F 4 .   ? 41.71642  -19.41539 22.70791  1.000 23.28722  ? 1997 HOH A O     1 
HETATM 3450 O O     . HOH F 4 .   ? 28.09644  -9.76151  24.29372  1.000 30.52023  ? 1998 HOH A O     1 
HETATM 3451 O O     . HOH F 4 .   ? 41.77988  -22.59751 19.37897  1.000 27.94215  ? 1999 HOH A O     1 
HETATM 3452 O O     . HOH F 4 .   ? 19.15573  -30.53307 -0.54515  1.000 39.42878  ? 2000 HOH A O     1 
HETATM 3453 O O     . HOH F 4 .   ? 16.98129  -29.02221 -3.50511  1.000 38.52804  ? 2001 HOH A O     1 
HETATM 3454 O O     . HOH F 4 .   ? 2.99090   -17.87422 37.00069  1.000 31.69802  ? 2002 HOH A O     1 
HETATM 3455 O O     . HOH F 4 .   ? 29.74035  -6.91199  -8.49679  1.000 27.30720  ? 2003 HOH A O     1 
HETATM 3456 O O     . HOH F 4 .   ? 16.31038  -29.43199 -6.04747  1.000 18.12074  ? 2004 HOH A O     1 
HETATM 3457 O O     . HOH F 4 .   ? 30.71768  -7.53798  -0.82203  1.000 37.29531  ? 2005 HOH A O     1 
HETATM 3458 O O     . HOH F 4 .   ? 31.27559  -12.58928 29.18266  1.000 53.25255  ? 2006 HOH A O     1 
HETATM 3459 O O     . HOH F 4 .   ? 18.43910  -29.41186 -14.06206 1.000 52.22339  ? 2007 HOH A O     1 
HETATM 3460 O O     . HOH F 4 .   ? 14.14538  -2.49413  22.56882  1.000 45.89605  ? 2008 HOH A O     1 
HETATM 3461 O O     . HOH F 4 .   ? 0.03639   -18.61302 -1.60608  1.000 45.47183  ? 2009 HOH A O     1 
HETATM 3462 O O     . HOH F 4 .   ? 42.62493  -21.57031 21.45342  1.000 33.67274  ? 2010 HOH A O     1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N N   . SER A 3   ? 0.53249 0.42718 0.25918 -0.05027 -0.00042 -0.02466 1009 SER A N   
2    C CA  . SER A 3   ? 0.51062 0.38480 0.25350 -0.05872 -0.00419 -0.03120 1009 SER A CA  
3    C C   . SER A 3   ? 0.42765 0.30092 0.23725 -0.05421 -0.00209 -0.01770 1009 SER A C   
4    O O   . SER A 3   ? 0.46342 0.33373 0.24949 -0.01044 0.00495  -0.02819 1009 SER A O   
5    C CB  . SER A 3   ? 0.56167 0.44476 0.26474 -0.02796 -0.00656 -0.04365 1009 SER A CB  
6    O OG  . SER A 3   ? 0.59990 0.48969 0.28062 -0.01121 -0.00401 -0.04627 1009 SER A OG  
7    N N   . LYS A 4   ? 0.29974 0.23873 0.20223 -0.07172 -0.01170 0.01177  1010 LYS A N   
8    C CA  A LYS A 4   ? 0.22582 0.19370 0.18104 -0.07423 -0.02373 0.03320  1010 LYS A CA  
9    C CA  B LYS A 4   ? 0.25143 0.22842 0.18573 -0.06830 -0.02567 0.02070  1010 LYS A CA  
10   C C   . LYS A 4   ? 0.19931 0.22940 0.16677 -0.06829 -0.04652 0.02176  1010 LYS A C   
11   O O   . LYS A 4   ? 0.19461 0.31090 0.17665 -0.07032 -0.06190 0.02594  1010 LYS A O   
12   C CB  A LYS A 4   ? 0.19631 0.20573 0.17521 -0.04629 -0.01846 0.04568  1010 LYS A CB  
13   C CB  B LYS A 4   ? 0.25336 0.24089 0.18760 -0.05890 -0.01875 0.02595  1010 LYS A CB  
14   C CG  A LYS A 4   ? 0.16872 0.19620 0.17188 -0.06931 -0.01686 0.04424  1010 LYS A CG  
15   C CG  B LYS A 4   ? 0.24472 0.23779 0.18892 -0.06414 -0.01621 0.02805  1010 LYS A CG  
16   C CD  A LYS A 4   ? 0.17349 0.23652 0.16851 -0.04904 -0.01930 0.03599  1010 LYS A CD  
17   C CD  B LYS A 4   ? 0.22710 0.21136 0.18785 -0.08734 -0.01438 0.02836  1010 LYS A CD  
18   C CE  A LYS A 4   ? 0.18910 0.25912 0.16802 -0.03103 -0.00948 0.05218  1010 LYS A CE  
19   C CE  B LYS A 4   ? 0.20808 0.19751 0.18684 -0.11117 -0.01256 0.02960  1010 LYS A CE  
20   N NZ  A LYS A 4   ? 0.17340 0.25112 0.16478 -0.04641 -0.00289 0.07064  1010 LYS A NZ  
21   N NZ  B LYS A 4   ? 0.19194 0.20048 0.18592 -0.11462 -0.01714 0.02215  1010 LYS A NZ  
22   N N   . VAL A 5   ? 0.16435 0.20184 0.13666 -0.04518 -0.03139 0.02711  1011 VAL A N   
23   C CA  . VAL A 5   ? 0.15876 0.21470 0.11868 -0.03527 -0.02270 0.02010  1011 VAL A CA  
24   C C   . VAL A 5   ? 0.13826 0.19940 0.09951 -0.04382 -0.02358 0.01387  1011 VAL A C   
25   O O   . VAL A 5   ? 0.15970 0.19482 0.08994 -0.03116 -0.01220 0.00392  1011 VAL A O   
26   C CB  . VAL A 5   ? 0.19051 0.23507 0.12504 -0.01390 -0.01234 0.01187  1011 VAL A CB  
27   C CG1 . VAL A 5   ? 0.16611 0.27062 0.12869 -0.03379 -0.00762 0.00481  1011 VAL A CG1 
28   C CG2 . VAL A 5   ? 0.21347 0.27473 0.13061 0.02239  -0.01981 0.00438  1011 VAL A CG2 
29   N N   . SER A 6   ? 0.14225 0.20046 0.10410 -0.02808 -0.02512 0.01879  1012 SER A N   
30   C CA  A SER A 6   ? 0.13171 0.20976 0.11192 -0.03008 -0.02705 0.02334  1012 SER A CA  
31   C CA  B SER A 6   ? 0.14734 0.20588 0.10987 -0.01968 -0.01984 0.02206  1012 SER A CA  
32   C C   . SER A 6   ? 0.13633 0.18909 0.11079 -0.02072 -0.00530 0.03132  1012 SER A C   
33   O O   . SER A 6   ? 0.16766 0.20814 0.12857 -0.02488 0.01687  0.01844  1012 SER A O   
34   C CB  A SER A 6   ? 0.15976 0.21833 0.12063 -0.03488 -0.04171 0.02860  1012 SER A CB  
35   C CB  B SER A 6   ? 0.17893 0.21729 0.11414 0.00343  -0.02709 0.01874  1012 SER A CB  
36   O OG  A SER A 6   ? 0.16145 0.25573 0.12621 -0.04577 -0.05563 0.02451  1012 SER A OG  
37   O OG  B SER A 6   ? 0.19594 0.24014 0.11754 0.02553  -0.03175 0.00993  1012 SER A OG  
38   N N   . VAL A 7   ? 0.12603 0.17373 0.10109 -0.00940 -0.02047 0.02837  1013 VAL A N   
39   C CA  . VAL A 7   ? 0.12226 0.17185 0.09520 -0.00441 -0.01704 0.02290  1013 VAL A CA  
40   C C   . VAL A 7   ? 0.10471 0.17674 0.10148 -0.00440 -0.00300 0.03091  1013 VAL A C   
41   O O   . VAL A 7   ? 0.11804 0.20450 0.12072 0.01196  0.01393  0.05049  1013 VAL A O   
42   C CB  . VAL A 7   ? 0.12456 0.18358 0.09243 -0.01627 -0.02703 0.02728  1013 VAL A CB  
43   C CG1 . VAL A 7   ? 0.13276 0.22477 0.09447 0.00064  -0.02990 0.03676  1013 VAL A CG1 
44   C CG2 . VAL A 7   ? 0.16870 0.19217 0.09701 -0.00173 -0.02163 0.00651  1013 VAL A CG2 
45   N N   . ALA A 8   ? 0.11152 0.15940 0.08783 0.00348  -0.00609 0.02386  1014 ALA A N   
46   C CA  . ALA A 8   ? 0.10567 0.17361 0.08640 0.00353  -0.01871 0.02181  1014 ALA A CA  
47   C C   . ALA A 8   ? 0.09554 0.16839 0.07663 -0.00122 -0.00532 0.01405  1014 ALA A C   
48   O O   . ALA A 8   ? 0.10568 0.18115 0.07707 0.00842  -0.00681 0.01598  1014 ALA A O   
49   C CB  . ALA A 8   ? 0.12323 0.17797 0.09484 0.00482  -0.02836 0.00193  1014 ALA A CB  
50   N N   . PRO A 9   ? 0.10001 0.16419 0.08539 0.00695  -0.00547 0.02078  1015 PRO A N   
51   C CA  . PRO A 9   ? 0.10676 0.18027 0.08834 0.01246  -0.00506 0.02215  1015 PRO A CA  
52   C C   . PRO A 9   ? 0.10534 0.16825 0.08271 0.02495  -0.00173 0.01262  1015 PRO A C   
53   O O   . PRO A 9   ? 0.11266 0.17191 0.08861 0.01960  -0.01941 0.00201  1015 PRO A O   
54   C CB  . PRO A 9   ? 0.11397 0.18955 0.09935 0.01073  0.00257  0.02933  1015 PRO A CB  
55   C CG  . PRO A 9   ? 0.11598 0.18742 0.10524 0.00035  -0.00553 0.02717  1015 PRO A CG  
56   C CD  . PRO A 9   ? 0.10494 0.18005 0.09427 0.00261  -0.01169 0.01986  1015 PRO A CD  
57   N N   . LEU A 10  ? 0.10963 0.17684 0.07408 0.00289  0.00492  0.01034  1016 LEU A N   
58   C CA  . LEU A 10  ? 0.15454 0.18588 0.08807 -0.03347 0.02071  -0.00540 1016 LEU A CA  
59   C C   . LEU A 10  ? 0.09770 0.17666 0.08301 -0.00322 -0.00289 0.00476  1016 LEU A C   
60   O O   . LEU A 10  ? 0.12068 0.17951 0.07598 0.00209  -0.00686 0.01055  1016 LEU A O   
61   C CB  . LEU A 10  ? 0.19510 0.24002 0.11432 -0.09295 0.04074  -0.03690 1016 LEU A CB  
62   C CG  . LEU A 10  ? 0.24321 0.28043 0.13564 -0.09528 0.03607  -0.02535 1016 LEU A CG  
63   C CD1 . LEU A 10  ? 0.26641 0.31106 0.14701 -0.06682 0.04048  -0.00826 1016 LEU A CD1 
64   C CD2 . LEU A 10  ? 0.27943 0.28305 0.13947 -0.07324 0.03539  -0.02030 1016 LEU A CD2 
65   N N   . HIS A 11  ? 0.11096 0.16701 0.08534 0.00559  -0.01343 0.00650  1017 HIS A N   
66   C CA  . HIS A 11  ? 0.13266 0.17873 0.08888 0.01647  -0.01435 0.01976  1017 HIS A CA  
67   C C   . HIS A 11  ? 0.13712 0.16351 0.08569 0.01488  -0.01503 0.01914  1017 HIS A C   
68   O O   . HIS A 11  ? 0.16637 0.16080 0.09422 0.01177  -0.02828 -0.00193 1017 HIS A O   
69   C CB  . HIS A 11  ? 0.14308 0.17927 0.08887 0.02355  -0.02299 0.01515  1017 HIS A CB  
70   C CG  . HIS A 11  ? 0.13173 0.18103 0.09433 0.00777  -0.02047 0.02894  1017 HIS A CG  
71   N ND1 . HIS A 11  ? 0.12163 0.18011 0.09736 0.00767  -0.01556 0.03065  1017 HIS A ND1 
72   C CD2 . HIS A 11  ? 0.15073 0.20346 0.09995 -0.01336 -0.02028 0.02591  1017 HIS A CD2 
73   C CE1 . HIS A 11  ? 0.13460 0.17347 0.10853 -0.00188 -0.01036 0.04199  1017 HIS A CE1 
74   N NE2 . HIS A 11  ? 0.14914 0.21144 0.10662 -0.01918 -0.01882 0.03787  1017 HIS A NE2 
75   N N   . LEU A 12  ? 0.10972 0.17996 0.08397 -0.00004 -0.01746 0.01532  1018 LEU A N   
76   C CA  . LEU A 12  ? 0.12930 0.17898 0.08086 -0.00888 -0.01139 0.01406  1018 LEU A CA  
77   C C   . LEU A 12  ? 0.12048 0.19812 0.08211 0.00567  -0.00924 0.01332  1018 LEU A C   
78   O O   . LEU A 12  ? 0.13088 0.23866 0.08516 -0.00666 -0.01511 -0.00243 1018 LEU A O   
79   C CB  . LEU A 12  ? 0.11777 0.19616 0.07682 0.00292  -0.01716 0.01038  1018 LEU A CB  
80   C CG  . LEU A 12  ? 0.12126 0.22180 0.08588 -0.01517 -0.00668 0.00991  1018 LEU A CG  
81   C CD1 . LEU A 12  ? 0.11777 0.22926 0.09453 -0.01706 0.00813  -0.02264 1018 LEU A CD1 
82   C CD2 . LEU A 12  ? 0.14020 0.23918 0.09479 0.00453  0.00168  0.02971  1018 LEU A CD2 
83   N N   . GLU A 13  ? 0.11562 0.17290 0.07400 0.00964  -0.00413 0.01671  1019 GLU A N   
84   C CA  . GLU A 13  ? 0.13424 0.17977 0.08285 0.02694  0.00173  0.00958  1019 GLU A CA  
85   C C   . GLU A 13  ? 0.13973 0.18490 0.10033 0.02285  -0.00710 -0.00655 1019 GLU A C   
86   O O   . GLU A 13  ? 0.20417 0.21396 0.09829 0.04173  0.01129  -0.00748 1019 GLU A O   
87   C CB  . GLU A 13  ? 0.13087 0.18064 0.08654 0.00445  0.00668  0.01655  1019 GLU A CB  
88   C CG  . GLU A 13  ? 0.13508 0.17152 0.08462 0.00883  -0.00084 0.01699  1019 GLU A CG  
89   C CD  . GLU A 13  ? 0.12034 0.18156 0.07303 0.01143  0.00454  0.02226  1019 GLU A CD  
90   O OE1 . GLU A 13  ? 0.13892 0.19578 0.07076 0.02244  0.00162  0.01210  1019 GLU A OE1 
91   O OE2 . GLU A 13  ? 0.12168 0.18491 0.08081 0.01432  -0.00031 0.01757  1019 GLU A OE2 
92   N N   . SER A 14  ? 0.14363 0.16650 0.12581 0.02644  -0.01913 -0.00895 1020 SER A N   
93   C CA  . SER A 14  ? 0.16015 0.18085 0.15100 0.03812  -0.03046 -0.02390 1020 SER A CA  
94   C C   . SER A 14  ? 0.17685 0.20627 0.16638 0.04219  -0.02776 -0.03966 1020 SER A C   
95   O O   . SER A 14  ? 0.21067 0.23713 0.17688 0.06602  -0.03237 -0.05820 1020 SER A O   
96   C CB  . SER A 14  ? 0.17850 0.19786 0.16545 0.03725  -0.05161 -0.02446 1020 SER A CB  
97   O OG  . SER A 14  ? 0.20726 0.26577 0.18070 0.03844  -0.05465 -0.01600 1020 SER A OG  
98   N N   . ALA A 15  ? 0.16137 0.22369 0.17464 -0.00057 -0.03194 -0.03692 1021 ALA A N   
99   C CA  . ALA A 15  ? 0.20373 0.25860 0.19092 -0.00116 -0.03687 -0.05127 1021 ALA A CA  
100  C C   . ALA A 15  ? 0.18643 0.26790 0.20129 0.01936  -0.03785 -0.07831 1021 ALA A C   
101  O O   . ALA A 15  ? 0.21687 0.29320 0.19171 0.04143  -0.03922 -0.06801 1021 ALA A O   
102  C CB  . ALA A 15  ? 0.21912 0.30552 0.19860 -0.03804 -0.03484 -0.04217 1021 ALA A CB  
103  N N   . LYS A 16  ? 0.20578 0.30138 0.22600 0.02685  -0.01857 -0.09242 1022 LYS A N   
104  C CA  . LYS A 16  ? 0.22757 0.32525 0.25318 0.00527  -0.00234 -0.08814 1022 LYS A CA  
105  C C   . LYS A 16  ? 0.19814 0.30707 0.21361 -0.00114 -0.00252 -0.07978 1022 LYS A C   
106  O O   . LYS A 16  ? 0.20625 0.33168 0.21065 -0.00639 0.01873  -0.05813 1022 LYS A O   
112  N N   A GLU A 17  ? 0.17373 0.28325 0.19631 -0.01803 -0.01066 -0.08366 1023 GLU A N   
113  N N   B GLU A 17  ? 0.19669 0.27758 0.20084 -0.00676 0.00170  -0.06330 1023 GLU A N   
114  C CA  A GLU A 17  ? 0.16739 0.29020 0.18250 -0.02369 -0.01099 -0.06781 1023 GLU A CA  
115  C CA  B GLU A 17  ? 0.20544 0.26530 0.18948 -0.00569 0.00953  -0.03673 1023 GLU A CA  
116  C C   A GLU A 17  ? 0.16024 0.25764 0.16515 -0.02008 -0.00702 -0.01730 1023 GLU A C   
117  C C   B GLU A 17  ? 0.18260 0.24842 0.17191 -0.00955 0.00704  0.00114  1023 GLU A C   
118  O O   A GLU A 17  ? 0.17596 0.25375 0.15159 0.02381  -0.01501 -0.02295 1023 GLU A O   
119  O O   B GLU A 17  ? 0.19590 0.24180 0.16270 0.01789  0.00522  0.00235  1023 GLU A O   
120  C CB  A GLU A 17  ? 0.21843 0.36104 0.19149 -0.01636 -0.00738 -0.08178 1023 GLU A CB  
121  C CB  B GLU A 17  ? 0.26626 0.28493 0.19854 0.00208  0.02104  -0.03900 1023 GLU A CB  
122  C CG  A GLU A 17  ? 0.27326 0.45384 0.20219 0.03256  -0.00057 -0.08558 1023 GLU A CG  
123  C CG  B GLU A 17  ? 0.32396 0.31252 0.20832 0.02767  0.03064  -0.03737 1023 GLU A CG  
124  C CD  A GLU A 17  ? 0.32370 0.55728 0.21264 0.08398  0.00628  -0.08236 1023 GLU A CD  
125  C CD  B GLU A 17  ? 0.37255 0.34050 0.21684 0.05292  0.03800  -0.03037 1023 GLU A CD  
126  O OE1 A GLU A 17  ? 0.34943 0.59095 0.21856 0.09968  0.00347  -0.07862 1023 GLU A OE1 
127  O OE1 B GLU A 17  ? 0.38478 0.35234 0.22166 0.06476  0.03746  -0.03214 1023 GLU A OE1 
128  O OE2 A GLU A 17  ? 0.34345 0.60170 0.21535 0.10535  0.01313  -0.08004 1023 GLU A OE2 
129  O OE2 B GLU A 17  ? 0.39049 0.35013 0.21917 0.05445  0.04373  -0.02394 1023 GLU A OE2 
130  N N   . PRO A 18  ? 0.16567 0.26718 0.16900 -0.01660 0.00440  0.02669  1024 PRO A N   
131  C CA  . PRO A 18  ? 0.17655 0.24829 0.17816 -0.02826 0.02400  0.04705  1024 PRO A CA  
132  C C   . PRO A 18  ? 0.19285 0.21795 0.17150 -0.01801 0.03280  0.02817  1024 PRO A C   
133  O O   . PRO A 18  ? 0.22222 0.22607 0.17106 -0.01049 0.03886  0.01827  1024 PRO A O   
134  C CB  . PRO A 18  ? 0.19572 0.28116 0.19087 -0.00863 0.00734  0.05904  1024 PRO A CB  
135  C CG  . PRO A 18  ? 0.18948 0.32017 0.18673 -0.00457 -0.02417 0.05774  1024 PRO A CG  
136  C CD  . PRO A 18  ? 0.18139 0.30197 0.17589 -0.02281 -0.02163 0.04335  1024 PRO A CD  
137  N N   . PRO A 19  ? 0.19458 0.22208 0.16457 -0.00357 0.02589  0.01774  1025 PRO A N   
138  C CA  . PRO A 19  ? 0.18129 0.22096 0.15144 -0.01569 0.00970  0.02302  1025 PRO A CA  
139  C C   . PRO A 19  ? 0.18470 0.19928 0.13232 -0.00621 0.00443  0.01785  1025 PRO A C   
140  O O   . PRO A 19  ? 0.19810 0.19532 0.13088 -0.01851 -0.01323 0.02595  1025 PRO A O   
141  C CB  . PRO A 19  ? 0.19710 0.27177 0.15743 -0.01917 -0.00454 0.00030  1025 PRO A CB  
142  C CG  . PRO A 19  ? 0.24819 0.29186 0.16803 0.02780  0.01730  -0.00339 1025 PRO A CG  
143  C CD  . PRO A 19  ? 0.22411 0.23716 0.16974 0.00860  0.02101  0.00222  1025 PRO A CD  
144  N N   . LEU A 20  ? 0.16928 0.21037 0.12274 -0.01353 0.01376  0.01671  1026 LEU A N   
145  C CA  . LEU A 20  ? 0.19478 0.20333 0.11232 -0.01111 0.01401  0.00836  1026 LEU A CA  
146  C C   . LEU A 20  ? 0.17734 0.17971 0.11501 -0.01314 0.01125  0.00485  1026 LEU A C   
147  O O   . LEU A 20  ? 0.19451 0.19179 0.12202 0.01349  0.02667  0.01258  1026 LEU A O   
148  C CB  . LEU A 20  ? 0.24817 0.23830 0.11376 -0.01520 0.01246  0.00639  1026 LEU A CB  
149  C CG  . LEU A 20  ? 0.28493 0.27288 0.12064 0.02044  0.00567  0.01128  1026 LEU A CG  
150  C CD1 . LEU A 20  ? 0.32837 0.32959 0.12086 0.05552  0.01327  0.01497  1026 LEU A CD1 
151  C CD2 . LEU A 20  ? 0.25417 0.22368 0.12805 -0.01878 -0.01434 0.00746  1026 LEU A CD2 
152  N N   . ASN A 21  ? 0.17085 0.18407 0.11426 -0.01224 -0.00177 0.00596  1027 ASN A N   
153  C CA  . ASN A 21  ? 0.16325 0.18806 0.11848 -0.03102 -0.00177 0.00073  1027 ASN A CA  
154  C C   . ASN A 21  ? 0.15885 0.17548 0.11836 -0.03236 0.00620  0.00153  1027 ASN A C   
155  O O   . ASN A 21  ? 0.20029 0.18587 0.12818 -0.04065 0.00217  0.00579  1027 ASN A O   
156  C CB  . ASN A 21  ? 0.18684 0.20803 0.12782 -0.04134 -0.01120 -0.00951 1027 ASN A CB  
157  C CG  . ASN A 21  ? 0.21916 0.23703 0.13453 -0.04777 -0.01728 -0.01178 1027 ASN A CG  
158  O OD1 . ASN A 21  ? 0.23235 0.28657 0.14414 -0.01656 -0.01586 -0.00961 1027 ASN A OD1 
159  N ND2 . ASN A 21  ? 0.24687 0.27034 0.13101 -0.03798 -0.00591 0.00953  1027 ASN A ND2 
160  N N   . THR A 22  ? 0.14624 0.18777 0.10367 -0.01736 0.00790  -0.00097 1028 THR A N   
161  C CA  . THR A 22  ? 0.15991 0.17389 0.10069 -0.02198 -0.00212 0.01193  1028 THR A CA  
162  C C   . THR A 22  ? 0.16733 0.17852 0.10690 -0.01026 -0.00006 0.01332  1028 THR A C   
163  O O   . THR A 22  ? 0.19216 0.19253 0.12693 -0.00927 0.00575  0.01672  1028 THR A O   
164  C CB  . THR A 22  ? 0.15629 0.17973 0.10002 -0.02487 -0.00209 0.01445  1028 THR A CB  
165  O OG1 . THR A 22  ? 0.17624 0.17709 0.09864 -0.01591 0.00395  0.00258  1028 THR A OG1 
166  C CG2 . THR A 22  ? 0.16795 0.21516 0.09889 -0.01802 -0.00046 0.02456  1028 THR A CG2 
167  N N   . TYR A 23  ? 0.15707 0.17904 0.10137 -0.01513 0.00341  0.00286  1029 TYR A N   
168  C CA  . TYR A 23  ? 0.15537 0.18877 0.09500 -0.01783 0.00553  0.00527  1029 TYR A CA  
169  C C   . TYR A 23  ? 0.17199 0.19442 0.09833 -0.02224 -0.00027 -0.00016 1029 TYR A C   
170  O O   . TYR A 23  ? 0.18299 0.20924 0.10163 -0.03045 -0.01449 0.01284  1029 TYR A O   
171  C CB  . TYR A 23  ? 0.15563 0.17821 0.09962 -0.02600 -0.00046 -0.00144 1029 TYR A CB  
172  C CG  . TYR A 23  ? 0.15885 0.17530 0.10250 -0.01567 0.00073  -0.00155 1029 TYR A CG  
173  C CD1 . TYR A 23  ? 0.16388 0.16102 0.10779 -0.03233 0.01001  -0.00549 1029 TYR A CD1 
174  C CD2 . TYR A 23  ? 0.17619 0.18696 0.11090 -0.01635 -0.00698 0.01047  1029 TYR A CD2 
175  C CE1 . TYR A 23  ? 0.17546 0.19792 0.11438 -0.00920 -0.00220 -0.01385 1029 TYR A CE1 
176  C CE2 . TYR A 23  ? 0.19108 0.19606 0.11885 -0.01116 -0.01349 0.01012  1029 TYR A CE2 
177  C CZ  . TYR A 23  ? 0.17477 0.20702 0.12534 -0.00944 -0.01596 -0.00651 1029 TYR A CZ  
178  O OH  . TYR A 23  ? 0.19553 0.25457 0.13791 0.00186  -0.03213 -0.00837 1029 TYR A OH  
179  N N   . LYS A 24  ? 0.20685 0.20470 0.10997 -0.05714 -0.01006 -0.00025 1030 LYS A N   
180  C CA  . LYS A 24  ? 0.20967 0.22332 0.13295 -0.06821 -0.02109 -0.01645 1030 LYS A CA  
181  C C   . LYS A 24  ? 0.21465 0.22212 0.14567 -0.04354 -0.02582 -0.03048 1030 LYS A C   
182  O O   . LYS A 24  ? 0.21101 0.20830 0.14176 -0.05308 -0.01299 -0.01846 1030 LYS A O   
183  C CB  . LYS A 24  ? 0.22690 0.27344 0.14718 -0.06208 -0.01562 -0.02731 1030 LYS A CB  
184  C CG  . LYS A 24  ? 0.27807 0.35349 0.16147 0.00466  -0.02019 -0.03968 1030 LYS A CG  
185  C CD  . LYS A 24  ? 0.31865 0.41738 0.17155 0.07294  -0.03107 -0.06099 1030 LYS A CD  
186  C CE  . LYS A 24  ? 0.36550 0.47849 0.18289 0.13371  -0.03495 -0.05550 1030 LYS A CE  
187  N NZ  . LYS A 24  ? 0.42374 0.53903 0.19423 0.16925  -0.04265 -0.04739 1030 LYS A NZ  
188  N N   . PRO A 25  ? 0.22035 0.26298 0.17025 -0.03002 -0.03713 -0.04686 1031 PRO A N   
189  C CA  . PRO A 25  ? 0.22392 0.30107 0.18919 -0.05935 -0.02699 -0.06372 1031 PRO A CA  
190  C C   . PRO A 25  ? 0.24017 0.30630 0.19901 -0.08889 -0.00535 -0.08087 1031 PRO A C   
191  O O   . PRO A 25  ? 0.24682 0.36665 0.20607 -0.04762 0.00506  -0.09651 1031 PRO A O   
192  C CB  . PRO A 25  ? 0.23691 0.33910 0.19353 -0.02242 -0.04357 -0.06235 1031 PRO A CB  
193  C CG  . PRO A 25  ? 0.24873 0.33028 0.19156 -0.00566 -0.05834 -0.05463 1031 PRO A CG  
194  C CD  . PRO A 25  ? 0.22507 0.29460 0.17982 -0.02911 -0.05877 -0.04909 1031 PRO A CD  
195  N N   . LYS A 26  ? 0.25676 0.30606 0.20167 -0.11646 0.02019  -0.05616 1032 LYS A N   
196  C CA  . LYS A 26  ? 0.31209 0.29870 0.20431 -0.14009 0.02796  -0.04844 1032 LYS A CA  
197  C C   . LYS A 26  ? 0.29305 0.29216 0.19373 -0.13152 0.04521  -0.03619 1032 LYS A C   
198  O O   . LYS A 26  ? 0.30030 0.31522 0.19966 -0.14903 0.05077  -0.02817 1032 LYS A O   
199  C CB  . LYS A 26  ? 0.37336 0.33197 0.21781 -0.15540 0.02028  -0.04721 1032 LYS A CB  
200  C CG  . LYS A 26  ? 0.44166 0.42604 0.23115 -0.10592 0.01368  -0.04514 1032 LYS A CG  
201  C CD  . LYS A 26  ? 0.50384 0.53834 0.24061 -0.03080 0.00998  -0.03200 1032 LYS A CD  
202  C CE  . LYS A 26  ? 0.55050 0.63207 0.24738 0.03334  0.00560  -0.01899 1032 LYS A CE  
203  N NZ  . LYS A 26  ? 0.57901 0.67979 0.25104 0.06577  0.00355  -0.01124 1032 LYS A NZ  
204  N N   . GLU A 27  ? 0.28434 0.25954 0.18007 -0.12599 0.04434  -0.02537 1033 GLU A N   
205  C CA  . GLU A 27  ? 0.29656 0.24367 0.17096 -0.09707 0.03310  0.00183  1033 GLU A CA  
206  C C   . GLU A 27  ? 0.22144 0.22945 0.14225 -0.07534 0.01689  -0.00571 1033 GLU A C   
207  O O   . GLU A 27  ? 0.20452 0.20104 0.14049 -0.04862 0.00697  -0.00427 1033 GLU A O   
208  C CB  . GLU A 27  ? 0.39975 0.27824 0.19377 -0.08595 0.04596  0.02701  1033 GLU A CB  
209  C CG  . GLU A 27  ? 0.52117 0.41489 0.20882 0.03596  0.04971  0.04589  1033 GLU A CG  
210  C CD  . GLU A 27  ? 0.63571 0.55615 0.22094 0.15021  0.04905  0.06055  1033 GLU A CD  
211  O OE1 . GLU A 27  ? 0.67578 0.60274 0.22619 0.18767  0.05112  0.05475  1033 GLU A OE1 
212  O OE2 . GLU A 27  ? 0.67169 0.62192 0.22818 0.19215  0.04651  0.07682  1033 GLU A OE2 
213  N N   . PRO A 28  ? 0.18259 0.22757 0.11706 -0.06386 0.01559  -0.00126 1034 PRO A N   
214  C CA  . PRO A 28  ? 0.16879 0.22096 0.10221 -0.04259 0.00735  0.01164  1034 PRO A CA  
215  C C   . PRO A 28  ? 0.16586 0.19877 0.08343 -0.03860 0.01190  0.01311  1034 PRO A C   
216  O O   . PRO A 28  ? 0.19968 0.21309 0.08197 -0.04453 -0.00664 0.02072  1034 PRO A O   
217  C CB  . PRO A 28  ? 0.15359 0.24122 0.11227 -0.04086 0.01011  0.00226  1034 PRO A CB  
218  C CG  . PRO A 28  ? 0.19115 0.27040 0.13002 -0.02611 0.01316  -0.00521 1034 PRO A CG  
219  C CD  . PRO A 28  ? 0.18598 0.23973 0.12627 -0.04418 0.01825  -0.00241 1034 PRO A CD  
220  N N   . PHE A 29  ? 0.15156 0.18456 0.08030 -0.03193 0.00713  0.00668  1035 PHE A N   
221  C CA  . PHE A 29  ? 0.15198 0.17632 0.08505 -0.02349 0.00553  0.01104  1035 PHE A CA  
222  C C   . PHE A 29  ? 0.14853 0.18523 0.08000 -0.02139 0.00131  0.00697  1035 PHE A C   
223  O O   . PHE A 29  ? 0.15640 0.20094 0.08351 -0.01390 -0.01070 0.01260  1035 PHE A O   
224  C CB  . PHE A 29  ? 0.15379 0.19117 0.08779 -0.01455 -0.00442 0.00612  1035 PHE A CB  
225  C CG  . PHE A 29  ? 0.14513 0.17362 0.08166 -0.01623 0.00899  0.01865  1035 PHE A CG  
226  C CD1 . PHE A 29  ? 0.17218 0.20618 0.09251 -0.01119 -0.00743 0.01775  1035 PHE A CD1 
227  C CD2 . PHE A 29  ? 0.12873 0.19429 0.08063 -0.02186 0.01612  0.01537  1035 PHE A CD2 
228  C CE1 . PHE A 29  ? 0.16822 0.21584 0.09636 -0.01165 -0.00733 0.01026  1035 PHE A CE1 
229  C CE2 . PHE A 29  ? 0.12873 0.20655 0.09142 -0.01467 0.00899  0.00260  1035 PHE A CE2 
230  C CZ  . PHE A 29  ? 0.14713 0.20615 0.09486 -0.01548 0.00737  0.00466  1035 PHE A CZ  
231  N N   . THR A 30  ? 0.13966 0.18272 0.07862 -0.01294 0.00548  0.01722  1036 THR A N   
232  C CA  . THR A 30  ? 0.13788 0.18895 0.08646 -0.02170 0.00768  0.00783  1036 THR A CA  
233  C C   . THR A 30  ? 0.12040 0.19402 0.07278 -0.01931 0.00128  0.01016  1036 THR A C   
234  O O   . THR A 30  ? 0.12541 0.22174 0.07487 -0.02201 -0.00958 0.02311  1036 THR A O   
235  C CB  . THR A 30  ? 0.16899 0.19281 0.10459 -0.03768 0.03804  0.01322  1036 THR A CB  
236  O OG1 . THR A 30  ? 0.20378 0.20960 0.12294 -0.04465 0.05077  0.00878  1036 THR A OG1 
237  C CG2 . THR A 30  ? 0.17149 0.20054 0.10776 -0.00752 0.04351  0.00549  1036 THR A CG2 
238  N N   . ALA A 31  ? 0.13220 0.16869 0.06578 -0.00621 0.00145  0.00889  1037 ALA A N   
239  C CA  . ALA A 31  ? 0.13607 0.16951 0.06870 -0.01276 0.01941  0.01098  1037 ALA A CA  
240  C C   . ALA A 31  ? 0.11725 0.17978 0.06620 -0.00410 0.00556  0.00151  1037 ALA A C   
241  O O   . ALA A 31  ? 0.11958 0.20264 0.07604 -0.02674 0.00762  -0.00768 1037 ALA A O   
242  C CB  . ALA A 31  ? 0.17689 0.17914 0.06727 0.00489  0.00870  0.01702  1037 ALA A CB  
243  N N   . THR A 32  ? 0.11666 0.18369 0.06151 -0.00611 0.00086  -0.00693 1038 THR A N   
244  C CA  . THR A 32  ? 0.10900 0.18131 0.06117 -0.01118 -0.00337 -0.00275 1038 THR A CA  
245  C C   . THR A 32  ? 0.10619 0.17093 0.06775 -0.00635 -0.00315 0.00136  1038 THR A C   
246  O O   . THR A 32  ? 0.10126 0.19957 0.07544 -0.00790 0.01823  0.01640  1038 THR A O   
247  C CB  . THR A 32  ? 0.11629 0.17938 0.06919 -0.00026 0.00109  0.00131  1038 THR A CB  
248  O OG1 . THR A 32  ? 0.12570 0.18376 0.07433 -0.01246 -0.00054 0.01158  1038 THR A OG1 
249  C CG2 . THR A 32  ? 0.12612 0.18825 0.07293 0.00170  -0.00597 -0.00638 1038 THR A CG2 
250  N N   . ILE A 33  ? 0.10833 0.17791 0.06864 -0.00767 -0.00402 0.01078  1039 ILE A N   
251  C CA  . ILE A 33  ? 0.10693 0.18613 0.07531 -0.00247 0.00626  0.01102  1039 ILE A CA  
252  C C   . ILE A 33  ? 0.11832 0.18212 0.06727 0.00260  0.00918  0.01979  1039 ILE A C   
253  O O   . ILE A 33  ? 0.13170 0.19636 0.06407 -0.01135 -0.00329 0.01123  1039 ILE A O   
254  C CB  . ILE A 33  ? 0.11312 0.20190 0.08202 -0.00843 0.00075  0.01789  1039 ILE A CB  
255  C CG1 . ILE A 33  ? 0.11631 0.25564 0.08393 -0.01577 -0.00737 0.01700  1039 ILE A CG1 
256  C CG2 . ILE A 33  ? 0.14256 0.19620 0.10002 0.01123  0.00923  0.02566  1039 ILE A CG2 
257  C CD1 . ILE A 33  ? 0.14642 0.31302 0.09114 -0.01772 -0.01418 0.00922  1039 ILE A CD1 
258  N N   . VAL A 34  ? 0.11557 0.18335 0.07390 -0.00507 0.00352  0.01097  1040 VAL A N   
259  C CA  . VAL A 34  ? 0.12290 0.18002 0.08563 -0.00018 0.00386  0.01042  1040 VAL A CA  
260  C C   . VAL A 34  ? 0.12889 0.19901 0.08315 -0.01367 0.00208  0.01062  1040 VAL A C   
261  O O   . VAL A 34  ? 0.16838 0.19452 0.08389 0.00485  -0.01284 -0.00290 1040 VAL A O   
262  C CB  . VAL A 34  ? 0.12277 0.19419 0.10173 -0.02265 0.00506  0.00756  1040 VAL A CB  
263  C CG1 . VAL A 34  ? 0.14560 0.21038 0.11005 -0.02140 0.00290  0.00122  1040 VAL A CG1 
264  C CG2 . VAL A 34  ? 0.13252 0.22304 0.10969 0.01238  0.00604  0.00015  1040 VAL A CG2 
265  N N   . SER A 35  ? 0.13020 0.18509 0.08358 -0.00337 -0.00606 0.01878  1041 SER A N   
266  C CA  . SER A 35  ? 0.14451 0.18680 0.08410 -0.00024 -0.00780 0.00992  1041 SER A CA  
267  C C   . SER A 35  ? 0.12571 0.19034 0.07446 0.00426  0.00475  0.00675  1041 SER A C   
268  O O   . SER A 35  ? 0.12750 0.19691 0.07430 0.00186  0.00377  0.00741  1041 SER A O   
269  C CB  . SER A 35  ? 0.15148 0.19412 0.10195 -0.01374 -0.00983 -0.00130 1041 SER A CB  
270  O OG  . SER A 35  ? 0.15091 0.19402 0.11110 -0.00301 0.00513  0.00934  1041 SER A OG  
271  N N   . VAL A 36  ? 0.13627 0.19071 0.07778 0.00613  0.01089  0.00996  1042 VAL A N   
272  C CA  . VAL A 36  ? 0.12809 0.18577 0.08994 0.01135  0.00719  0.01211  1042 VAL A CA  
273  C C   . VAL A 36  ? 0.14063 0.18124 0.08943 0.00764  0.00917  0.01675  1042 VAL A C   
274  O O   . VAL A 36  ? 0.19699 0.20160 0.08996 0.02774  0.01794  0.00148  1042 VAL A O   
275  C CB  . VAL A 36  ? 0.13603 0.22404 0.10463 0.00217  0.01030  0.01667  1042 VAL A CB  
276  C CG1 . VAL A 36  ? 0.14030 0.25743 0.11161 0.00354  -0.00549 0.00510  1042 VAL A CG1 
277  C CG2 . VAL A 36  ? 0.15653 0.20706 0.11229 0.00539  0.01060  0.01608  1042 VAL A CG2 
278  N N   . GLU A 37  ? 0.15175 0.18801 0.09662 0.01562  -0.00959 0.02414  1043 GLU A N   
279  C CA  A GLU A 37  ? 0.18869 0.19314 0.10235 0.02178  -0.01379 0.01265  1043 GLU A CA  
280  C CA  B GLU A 37  ? 0.17560 0.19173 0.10454 0.02003  -0.00971 0.01514  1043 GLU A CA  
281  C C   . GLU A 37  ? 0.16198 0.20630 0.09620 0.03316  -0.00166 0.01158  1043 GLU A C   
282  O O   . GLU A 37  ? 0.20828 0.24366 0.09722 0.07754  -0.01526 -0.02125 1043 GLU A O   
283  C CB  A GLU A 37  ? 0.24412 0.21287 0.12128 0.02913  -0.03126 0.00695  1043 GLU A CB  
284  C CB  B GLU A 37  ? 0.20554 0.19786 0.12620 0.02152  -0.01959 0.01445  1043 GLU A CB  
285  C CG  A GLU A 37  ? 0.29123 0.23940 0.13731 0.03684  -0.03366 0.00524  1043 GLU A CG  
286  C CG  B GLU A 37  ? 0.22458 0.21039 0.14489 0.01964  -0.01489 0.02073  1043 GLU A CG  
287  C CD  A GLU A 37  ? 0.33231 0.27539 0.14975 0.05777  -0.03649 -0.00262 1043 GLU A CD  
288  C CD  B GLU A 37  ? 0.23438 0.22978 0.15874 0.01210  -0.00880 0.02955  1043 GLU A CD  
289  O OE1 A GLU A 37  ? 0.34330 0.30858 0.15854 0.06424  -0.03995 -0.01842 1043 GLU A OE1 
290  O OE1 B GLU A 37  ? 0.25244 0.27229 0.16581 0.01624  -0.00598 0.03806  1043 GLU A OE1 
291  O OE2 A GLU A 37  ? 0.35353 0.27275 0.15030 0.05946  -0.02704 -0.00218 1043 GLU A OE2 
292  O OE2 B GLU A 37  ? 0.20569 0.19698 0.16380 -0.01192 -0.01126 0.02284  1043 GLU A OE2 
293  N N   . SER A 38  ? 0.17242 0.21873 0.09521 0.04448  0.01598  0.01257  1044 SER A N   
294  C CA  . SER A 38  ? 0.16072 0.22930 0.09876 0.05536  0.01539  0.02537  1044 SER A CA  
295  C C   . SER A 38  ? 0.16112 0.21740 0.09290 0.04119  0.00096  0.00878  1044 SER A C   
296  O O   . SER A 38  ? 0.20249 0.23194 0.09115 0.02939  -0.00427 0.00274  1044 SER A O   
297  C CB  . SER A 38  ? 0.19125 0.26633 0.11341 0.08689  0.01743  0.03292  1044 SER A CB  
298  O OG  . SER A 38  ? 0.17488 0.27968 0.12521 0.08240  0.00900  0.02960  1044 SER A OG  
299  N N   . LEU A 39  ? 0.14267 0.20795 0.09006 0.02869  0.00417  0.02306  1045 LEU A N   
300  C CA  . LEU A 39  ? 0.14300 0.21346 0.09731 0.03301  0.01064  0.02043  1045 LEU A CA  
301  C C   . LEU A 39  ? 0.16141 0.22340 0.10924 0.04016  0.01292  0.01169  1045 LEU A C   
302  O O   . LEU A 39  ? 0.16954 0.22248 0.11913 0.03837  0.01474  0.02031  1045 LEU A O   
303  C CB  . LEU A 39  ? 0.13582 0.19770 0.10007 0.03892  -0.00282 0.00652  1045 LEU A CB  
304  C CG  . LEU A 39  ? 0.13362 0.20159 0.10688 0.02396  -0.00210 0.01067  1045 LEU A CG  
305  C CD1 . LEU A 39  ? 0.15378 0.19811 0.10438 0.03602  0.01625  0.00904  1045 LEU A CD1 
306  C CD2 . LEU A 39  ? 0.14414 0.21934 0.11625 0.03324  -0.00807 0.01955  1045 LEU A CD2 
307  N N   . VAL A 40  ? 0.17210 0.21706 0.10875 0.06163  0.01031  0.01333  1046 VAL A N   
308  C CA  . VAL A 40  ? 0.17138 0.22350 0.11325 0.05967  0.00748  0.01810  1046 VAL A CA  
309  C C   . VAL A 40  ? 0.20807 0.23753 0.11944 0.07776  0.01118  0.02011  1046 VAL A C   
310  O O   . VAL A 40  ? 0.22837 0.26817 0.11632 0.08592  0.02011  0.01864  1046 VAL A O   
311  C CB  . VAL A 40  ? 0.16985 0.23302 0.11849 0.04444  -0.00377 0.01131  1046 VAL A CB  
312  C CG1 . VAL A 40  ? 0.21100 0.27171 0.12148 0.09782  -0.01200 -0.00128 1046 VAL A CG1 
313  C CG2 . VAL A 40  ? 0.19999 0.24984 0.12479 0.05484  -0.01145 0.01515  1046 VAL A CG2 
314  N N   . GLY A 41  ? 0.23488 0.23751 0.13292 0.09777  0.00926  0.01896  1047 GLY A N   
315  C CA  . GLY A 41  ? 0.26960 0.24790 0.15280 0.11049  0.02326  0.00786  1047 GLY A CA  
316  C C   . GLY A 41  ? 0.28219 0.29278 0.17359 0.13362  0.03262  0.00667  1047 GLY A C   
317  O O   . GLY A 41  ? 0.25317 0.30126 0.17186 0.11998  0.03313  0.01398  1047 GLY A O   
318  N N   . PRO A 42  ? 0.30521 0.33027 0.19661 0.16010  0.04040  -0.00215 1048 PRO A N   
319  C CA  . PRO A 42  ? 0.30172 0.36966 0.21194 0.14940  0.05473  0.00764  1048 PRO A CA  
320  C C   . PRO A 42  ? 0.28373 0.39073 0.22284 0.15894  0.04987  0.03019  1048 PRO A C   
321  O O   . PRO A 42  ? 0.30311 0.41414 0.22965 0.15421  0.04939  0.04030  1048 PRO A O   
322  C CB  . PRO A 42  ? 0.33206 0.37083 0.21569 0.14632  0.06098  -0.00636 1048 PRO A CB  
323  C CG  . PRO A 42  ? 0.36059 0.35909 0.21538 0.15331  0.05071  -0.01796 1048 PRO A CG  
324  C CD  . PRO A 42  ? 0.34521 0.32119 0.20755 0.17473  0.03911  -0.01976 1048 PRO A CD  
325  N N   . LYS A 43  ? 0.29644 0.38814 0.22827 0.19186  0.03509  0.03833  1049 LYS A N   
326  C CA  . LYS A 43  ? 0.31018 0.38248 0.23304 0.18033  0.02936  0.04976  1049 LYS A CA  
327  C C   . LYS A 43  ? 0.25175 0.38933 0.21913 0.16161  0.01930  0.05767  1049 LYS A C   
328  O O   . LYS A 43  ? 0.26175 0.41045 0.21536 0.17805  0.01495  0.06411  1049 LYS A O   
329  C CB  . LYS A 43  ? 0.36921 0.39199 0.25071 0.19817  0.02544  0.04988  1049 LYS A CB  
330  C CG  . LYS A 43  ? 0.43918 0.42820 0.26456 0.19566  0.02869  0.04991  1049 LYS A CG  
331  C CD  . LYS A 43  ? 0.50954 0.45680 0.27578 0.19515  0.02987  0.04518  1049 LYS A CD  
332  C CE  . LYS A 43  ? 0.55953 0.48315 0.28412 0.18117  0.03195  0.04334  1049 LYS A CE  
333  N NZ  . LYS A 43  ? 0.58605 0.50890 0.28879 0.17948  0.03078  0.04354  1049 LYS A NZ  
334  N N   . ALA A 44  ? 0.22423 0.36651 0.20887 0.13996  0.01275  0.06413  1050 ALA A N   
335  C CA  . ALA A 44  ? 0.20305 0.35498 0.20041 0.10993  0.00247  0.06226  1050 ALA A CA  
336  C C   . ALA A 44  ? 0.19689 0.39761 0.20272 0.12159  0.00011  0.05574  1050 ALA A C   
337  O O   . ALA A 44  ? 0.21694 0.41516 0.20085 0.13400  0.01404  0.04639  1050 ALA A O   
338  C CB  . ALA A 44  ? 0.19267 0.32963 0.19338 0.10823  -0.00528 0.06657  1050 ALA A CB  
339  N N   . PRO A 45  ? 0.22687 0.45551 0.20670 0.10353  -0.01276 0.05136  1051 PRO A N   
340  C CA  . PRO A 45  ? 0.23214 0.48950 0.20863 0.08763  -0.02220 0.05159  1051 PRO A CA  
341  C C   . PRO A 45  ? 0.23002 0.50492 0.21305 0.10314  -0.03285 0.03984  1051 PRO A C   
342  O O   . PRO A 45  ? 0.24767 0.55901 0.22539 0.13425  -0.01922 0.04061  1051 PRO A O   
343  C CB  . PRO A 45  ? 0.27759 0.50143 0.20895 0.07563  -0.02071 0.04865  1051 PRO A CB  
344  C CG  . PRO A 45  ? 0.27990 0.49577 0.21042 0.06444  -0.02186 0.04401  1051 PRO A CG  
345  C CD  . PRO A 45  ? 0.26108 0.47505 0.20747 0.07823  -0.01947 0.04595  1051 PRO A CD  
346  N N   . GLY A 46  ? 0.21523 0.45886 0.20549 0.08865  -0.04879 0.02358  1052 GLY A N   
347  C CA  . GLY A 46  ? 0.18949 0.41787 0.19588 0.06632  -0.04059 0.01751  1052 GLY A CA  
348  C C   . GLY A 46  ? 0.15059 0.35650 0.17920 0.04149  -0.02835 0.01411  1052 GLY A C   
349  O O   . GLY A 46  ? 0.16580 0.35059 0.17735 0.03419  -0.04370 0.02156  1052 GLY A O   
350  N N   . GLU A 47  ? 0.13972 0.32005 0.16680 0.03240  -0.00586 0.00879  1053 GLU A N   
351  C CA  A GLU A 47  ? 0.14366 0.30152 0.15596 0.03219  -0.00028 0.01061  1053 GLU A CA  
352  C CA  B GLU A 47  ? 0.12739 0.29796 0.15434 0.01662  0.00822  0.01891  1053 GLU A CA  
353  C C   . GLU A 47  ? 0.12211 0.26133 0.14578 0.01662  -0.00315 0.01530  1053 GLU A C   
354  O O   . GLU A 47  ? 0.12667 0.29067 0.15828 0.01898  0.00076  0.01540  1053 GLU A O   
355  C CB  A GLU A 47  ? 0.19719 0.32784 0.15517 0.04330  0.00280  0.00499  1053 GLU A CB  
356  C CB  B GLU A 47  ? 0.17067 0.32660 0.15087 -0.00371 0.02184  0.02619  1053 GLU A CB  
357  C CG  A GLU A 47  ? 0.25952 0.34619 0.15431 0.06621  -0.00505 0.00014  1053 GLU A CG  
358  C CG  B GLU A 47  ? 0.23468 0.34409 0.14767 0.00665  0.01505  0.03634  1053 GLU A CG  
359  C CD  A GLU A 47  ? 0.30710 0.36196 0.15368 0.08340  -0.01157 -0.00500 1053 GLU A CD  
360  C CD  B GLU A 47  ? 0.28001 0.36238 0.14797 0.01292  0.00981  0.04304  1053 GLU A CD  
361  O OE1 A GLU A 47  ? 0.30622 0.36043 0.15303 0.08319  -0.01867 -0.01165 1053 GLU A OE1 
362  O OE1 B GLU A 47  ? 0.29178 0.35341 0.14414 0.00416  0.01659  0.05822  1053 GLU A OE1 
363  O OE2 A GLU A 47  ? 0.34180 0.37706 0.15337 0.09729  -0.02176 -0.00804 1053 GLU A OE2 
364  O OE2 B GLU A 47  ? 0.31744 0.37896 0.15080 0.04527  0.01060  0.04503  1053 GLU A OE2 
365  N N   . THR A 48  ? 0.11605 0.25634 0.12583 0.02104  -0.01266 0.02108  1054 THR A N   
366  C CA  . THR A 48  ? 0.10245 0.23541 0.10621 0.03932  -0.00860 0.02553  1054 THR A CA  
367  C C   . THR A 48  ? 0.10875 0.20930 0.10667 0.01399  0.00230  0.02076  1054 THR A C   
368  O O   . THR A 48  ? 0.13475 0.22748 0.10023 0.02036  -0.00318 0.01956  1054 THR A O   
369  C CB  . THR A 48  ? 0.11605 0.24400 0.09972 0.02444  -0.00750 0.02785  1054 THR A CB  
370  O OG1 . THR A 48  ? 0.14306 0.26858 0.10222 0.02241  -0.01434 0.02778  1054 THR A OG1 
371  C CG2 . THR A 48  ? 0.12314 0.23691 0.10058 0.02460  -0.00031 0.02714  1054 THR A CG2 
372  N N   . CYS A 49  ? 0.09648 0.22493 0.12594 0.02256  0.00714  0.02536  1055 CYS A N   
373  C CA  A CYS A 49  ? 0.06775 0.19645 0.11041 0.00603  0.02309  0.03575  1055 CYS A CA  
374  C CA  B CYS A 49  ? 0.19162 0.27326 0.20913 0.02549  0.00337  0.02257  1055 CYS A CA  
375  C C   . CYS A 49  ? 0.11316 0.20075 0.12708 0.02602  0.00512  0.01721  1055 CYS A C   
376  O O   . CYS A 49  ? 0.11172 0.22763 0.11160 0.01633  0.01146  0.00882  1055 CYS A O   
381  N N   . HIS A 50  ? 0.10421 0.19887 0.09939 0.02461  -0.00493 0.01118  1056 HIS A N   
382  C CA  . HIS A 50  ? 0.10463 0.17474 0.08787 0.00856  -0.00186 0.01263  1056 HIS A CA  
383  C C   . HIS A 50  ? 0.10641 0.17837 0.07937 0.00181  0.00410  0.01230  1056 HIS A C   
384  O O   . HIS A 50  ? 0.13185 0.20016 0.07179 0.01224  -0.00203 0.00816  1056 HIS A O   
385  C CB  . HIS A 50  ? 0.12315 0.18499 0.09447 0.02158  0.00245  0.02349  1056 HIS A CB  
386  C CG  . HIS A 50  ? 0.12504 0.17378 0.09602 -0.00087 0.00600  0.02958  1056 HIS A CG  
387  N ND1 . HIS A 50  ? 0.13559 0.17278 0.09900 0.00650  0.00916  0.02653  1056 HIS A ND1 
388  C CD2 . HIS A 50  ? 0.13348 0.19841 0.10989 0.01291  -0.00086 0.02705  1056 HIS A CD2 
389  C CE1 . HIS A 50  ? 0.12379 0.18643 0.11388 0.00201  0.00236  0.02451  1056 HIS A CE1 
390  N NE2 . HIS A 50  ? 0.12505 0.18643 0.12090 0.00392  0.00562  0.02838  1056 HIS A NE2 
391  N N   . ILE A 51  ? 0.10827 0.18656 0.08541 0.01620  -0.00301 0.01972  1057 ILE A N   
392  C CA  . ILE A 51  ? 0.12040 0.19054 0.09665 0.00995  0.00624  0.02572  1057 ILE A CA  
393  C C   . ILE A 51  ? 0.12269 0.17540 0.07860 0.00844  -0.00132 0.01929  1057 ILE A C   
394  O O   . ILE A 51  ? 0.12625 0.20272 0.07366 0.01343  0.00389  0.00255  1057 ILE A O   
395  C CB  . ILE A 51  ? 0.11759 0.22755 0.13897 -0.00368 0.02553  0.04287  1057 ILE A CB  
396  C CG1 . ILE A 51  ? 0.18555 0.28768 0.15376 0.00791  0.02143  0.03835  1057 ILE A CG1 
397  C CG2 . ILE A 51  ? 0.16756 0.23779 0.14808 -0.00329 0.02987  0.03870  1057 ILE A CG2 
398  C CD1 . ILE A 51  ? 0.24012 0.32677 0.15693 0.02920  0.02367  0.03144  1057 ILE A CD1 
399  N N   . VAL A 52  ? 0.12897 0.18240 0.07445 0.01573  0.00125  0.01616  1058 VAL A N   
400  C CA  . VAL A 52  ? 0.11740 0.17253 0.07509 0.00045  -0.00157 0.00655  1058 VAL A CA  
401  C C   . VAL A 52  ? 0.10850 0.17126 0.07649 -0.00521 -0.00184 0.01613  1058 VAL A C   
402  O O   . VAL A 52  ? 0.12028 0.20402 0.07558 0.00268  0.00607  0.02284  1058 VAL A O   
403  C CB  . VAL A 52  ? 0.13585 0.19010 0.08332 0.00258  0.00744  0.01611  1058 VAL A CB  
404  C CG1 . VAL A 52  ? 0.15035 0.19777 0.08432 -0.01489 -0.00007 0.00117  1058 VAL A CG1 
405  C CG2 . VAL A 52  ? 0.18409 0.19739 0.08898 -0.00615 0.00153  0.02459  1058 VAL A CG2 
406  N N   . ILE A 53  ? 0.10632 0.17496 0.07648 -0.00042 0.00807  0.01420  1059 ILE A N   
407  C CA  . ILE A 53  ? 0.10858 0.17329 0.08311 -0.00124 0.00565  0.02128  1059 ILE A CA  
408  C C   . ILE A 53  ? 0.11237 0.18691 0.07067 -0.00042 0.00166  0.02138  1059 ILE A C   
409  O O   . ILE A 53  ? 0.09899 0.20770 0.07065 -0.00204 0.01153  0.02980  1059 ILE A O   
410  C CB  . ILE A 53  ? 0.11139 0.17989 0.10326 -0.01106 -0.00456 0.01662  1059 ILE A CB  
411  C CG1 . ILE A 53  ? 0.12884 0.21748 0.12186 -0.00829 -0.01867 0.01042  1059 ILE A CG1 
412  C CG2 . ILE A 53  ? 0.13081 0.18863 0.11394 -0.01268 0.00384  0.02798  1059 ILE A CG2 
413  C CD1 . ILE A 53  ? 0.16767 0.24011 0.13677 0.00286  -0.04469 -0.00842 1059 ILE A CD1 
414  N N   . ASP A 54  ? 0.11120 0.19349 0.07061 -0.00944 0.00416  0.01890  1060 ASP A N   
415  C CA  . ASP A 54  ? 0.10469 0.20531 0.07235 -0.00406 -0.00153 0.02375  1060 ASP A CA  
416  C C   . ASP A 54  ? 0.10892 0.19585 0.07585 -0.00361 0.00582  0.02980  1060 ASP A C   
417  O O   . ASP A 54  ? 0.12256 0.19300 0.09040 0.00025  0.01116  0.03401  1060 ASP A O   
418  C CB  . ASP A 54  ? 0.13663 0.22293 0.08111 0.00148  -0.00823 0.02308  1060 ASP A CB  
419  C CG  . ASP A 54  ? 0.15549 0.19393 0.08768 -0.00924 -0.01538 0.02716  1060 ASP A CG  
420  O OD1 . ASP A 54  ? 0.15544 0.25245 0.09986 0.02115  -0.02021 0.02395  1060 ASP A OD1 
421  O OD2 . ASP A 54  ? 0.19487 0.29902 0.09161 0.04274  -0.01740 0.00769  1060 ASP A OD2 
422  N N   . HIS A 55  ? 0.11763 0.18282 0.08093 -0.01052 0.00854  0.02122  1061 HIS A N   
423  C CA  . HIS A 55  ? 0.13700 0.18575 0.09049 0.00354  0.01132  0.02460  1061 HIS A CA  
424  C C   . HIS A 55  ? 0.13582 0.20273 0.09699 0.00354  0.02875  0.02744  1061 HIS A C   
425  O O   . HIS A 55  ? 0.15295 0.20337 0.11260 0.01656  0.02691  0.02999  1061 HIS A O   
426  C CB  . HIS A 55  ? 0.12499 0.21291 0.09162 -0.00876 0.01429  0.01766  1061 HIS A CB  
427  C CG  . HIS A 55  ? 0.11757 0.17612 0.08411 -0.00140 0.00602  0.00625  1061 HIS A CG  
428  N ND1 . HIS A 55  ? 0.13349 0.16758 0.08404 -0.01524 0.00555  0.01146  1061 HIS A ND1 
429  C CD2 . HIS A 55  ? 0.11730 0.18700 0.07988 -0.01079 -0.00273 0.01205  1061 HIS A CD2 
430  C CE1 . HIS A 55  ? 0.14246 0.17373 0.07572 0.00428  -0.00244 0.02307  1061 HIS A CE1 
431  N NE2 . HIS A 55  ? 0.13106 0.17277 0.07219 0.00289  -0.00708 0.02200  1061 HIS A NE2 
432  N N   . GLY A 56  ? 0.14162 0.23102 0.09389 0.02668  0.00233  0.00810  1062 GLY A N   
433  C CA  . GLY A 56  ? 0.15552 0.25324 0.09179 0.03491  -0.00381 0.00591  1062 GLY A CA  
434  C C   . GLY A 56  ? 0.16640 0.22017 0.08563 0.03461  -0.01454 -0.00344 1062 GLY A C   
435  O O   . GLY A 56  ? 0.18506 0.23947 0.09251 0.04487  -0.01329 0.00793  1062 GLY A O   
436  N N   . GLY A 57  ? 0.13861 0.19129 0.08250 -0.00573 -0.00541 0.00218  1063 GLY A N   
437  C CA  . GLY A 57  ? 0.13445 0.18970 0.08808 -0.00239 -0.00446 0.00167  1063 GLY A CA  
438  C C   . GLY A 57  ? 0.13143 0.17895 0.07572 -0.00148 -0.00432 0.01706  1063 GLY A C   
439  O O   . GLY A 57  ? 0.13866 0.19101 0.07706 0.00335  0.00095  0.01104  1063 GLY A O   
440  N N   . ASN A 58  ? 0.12892 0.17907 0.07664 -0.01153 0.00073  0.02022  1064 ASN A N   
441  C CA  . ASN A 58  ? 0.14798 0.17292 0.08357 -0.00982 -0.00129 0.02747  1064 ASN A CA  
442  C C   . ASN A 58  ? 0.14821 0.17002 0.08315 -0.00609 0.00786  0.02159  1064 ASN A C   
443  O O   . ASN A 58  ? 0.16334 0.16653 0.09362 -0.01745 -0.00057 0.01555  1064 ASN A O   
444  C CB  . ASN A 58  ? 0.16973 0.20764 0.09022 -0.01584 0.00242  0.04867  1064 ASN A CB  
445  C CG  . ASN A 58  ? 0.21158 0.23509 0.10212 0.01392  0.01072  0.05776  1064 ASN A CG  
446  O OD1 . ASN A 58  ? 0.26898 0.28857 0.11837 0.07623  0.00015  0.04941  1064 ASN A OD1 
447  N ND2 . ASN A 58  ? 0.21695 0.24738 0.10590 0.01517  0.00190  0.03636  1064 ASN A ND2 
448  N N   . VAL A 59  ? 0.13042 0.17594 0.08325 -0.01327 0.00419  0.02371  1065 VAL A N   
449  C CA  . VAL A 59  ? 0.12320 0.17856 0.07903 -0.01341 0.00875  0.03410  1065 VAL A CA  
450  C C   . VAL A 59  ? 0.13291 0.17163 0.07459 -0.00946 -0.00111 0.01568  1065 VAL A C   
451  O O   . VAL A 59  ? 0.13400 0.16634 0.08282 -0.01410 0.00009  0.01581  1065 VAL A O   
452  C CB  . VAL A 59  ? 0.12463 0.18479 0.09070 -0.02698 0.00752  0.02765  1065 VAL A CB  
453  C CG1 . VAL A 59  ? 0.13852 0.19421 0.09162 -0.03311 -0.00736 0.01278  1065 VAL A CG1 
454  C CG2 . VAL A 59  ? 0.14549 0.18670 0.09104 -0.01698 0.01180  0.02033  1065 VAL A CG2 
455  N N   . PRO A 60  ? 0.13123 0.15667 0.07682 -0.01425 0.00625  0.01684  1066 PRO A N   
456  C CA  . PRO A 60  ? 0.12971 0.16889 0.07865 -0.01520 -0.00116 0.01621  1066 PRO A CA  
457  C C   . PRO A 60  ? 0.12503 0.15425 0.07100 -0.02133 -0.00525 0.01303  1066 PRO A C   
458  O O   . PRO A 60  ? 0.16091 0.15707 0.07690 -0.01620 -0.00916 0.01556  1066 PRO A O   
459  C CB  . PRO A 60  ? 0.13014 0.16686 0.08586 -0.00993 0.00007  0.01658  1066 PRO A CB  
460  C CG  . PRO A 60  ? 0.13569 0.17365 0.09012 -0.00216 0.00540  0.02198  1066 PRO A CG  
461  C CD  . PRO A 60  ? 0.12997 0.16620 0.08224 -0.00760 0.00708  0.02309  1066 PRO A CD  
462  N N   . TYR A 61  ? 0.12279 0.15181 0.06336 -0.01864 -0.00356 0.01653  1067 TYR A N   
463  C CA  . TYR A 61  ? 0.11903 0.16324 0.06896 -0.00801 -0.00726 0.01951  1067 TYR A CA  
464  C C   . TYR A 61  ? 0.10443 0.16745 0.07013 -0.00287 -0.00130 0.01367  1067 TYR A C   
465  O O   . TYR A 61  ? 0.12169 0.16724 0.06785 -0.01282 -0.00962 0.01234  1067 TYR A O   
466  C CB  . TYR A 61  ? 0.12272 0.16001 0.07514 -0.01399 -0.00548 0.00857  1067 TYR A CB  
467  C CG  . TYR A 61  ? 0.09418 0.16846 0.07719 -0.01932 -0.00213 0.01349  1067 TYR A CG  
468  C CD1 . TYR A 61  ? 0.10099 0.16176 0.07550 -0.00646 0.00344  0.01228  1067 TYR A CD1 
469  C CD2 . TYR A 61  ? 0.09543 0.17660 0.07506 -0.00858 -0.00313 0.00857  1067 TYR A CD2 
470  C CE1 . TYR A 61  ? 0.09705 0.16161 0.07799 -0.00722 -0.00027 0.01029  1067 TYR A CE1 
471  C CE2 . TYR A 61  ? 0.10613 0.17227 0.07182 -0.00666 0.00838  0.01620  1067 TYR A CE2 
472  C CZ  . TYR A 61  ? 0.09119 0.16251 0.06987 -0.01228 0.00247  0.01356  1067 TYR A CZ  
473  O OH  . TYR A 61  ? 0.10358 0.16569 0.07002 -0.00755 0.00179  0.00724  1067 TYR A OH  
474  N N   . TRP A 62  ? 0.11865 0.16858 0.06841 -0.01705 0.00131  0.01410  1068 TRP A N   
475  C CA  . TRP A 62  ? 0.12568 0.17000 0.06619 -0.00968 -0.00031 0.01722  1068 TRP A CA  
476  C C   . TRP A 62  ? 0.10659 0.16609 0.06045 -0.01349 0.00148  0.01534  1068 TRP A C   
477  O O   . TRP A 62  ? 0.11727 0.17454 0.07033 -0.01345 -0.00129 0.02067  1068 TRP A O   
478  C CB  . TRP A 62  ? 0.11816 0.17114 0.07934 0.00356  -0.00254 0.01996  1068 TRP A CB  
479  C CG  . TRP A 62  ? 0.11337 0.18370 0.09576 -0.00807 0.00179  0.01814  1068 TRP A CG  
480  C CD1 . TRP A 62  ? 0.12388 0.20982 0.11238 0.01674  -0.00557 0.01648  1068 TRP A CD1 
481  C CD2 . TRP A 62  ? 0.13748 0.18375 0.10859 0.00232  0.00836  0.00793  1068 TRP A CD2 
482  N NE1 . TRP A 62  ? 0.13869 0.22956 0.12574 0.01186  -0.00703 0.01511  1068 TRP A NE1 
483  C CE2 . TRP A 62  ? 0.14681 0.20111 0.12328 0.00842  -0.00004 -0.00191 1068 TRP A CE2 
484  C CE3 . TRP A 62  ? 0.16967 0.23275 0.10943 0.02998  0.00486  -0.01301 1068 TRP A CE3 
485  C CZ2 . TRP A 62  ? 0.17645 0.24063 0.13332 0.02967  0.00493  -0.01102 1068 TRP A CZ2 
486  C CZ3 . TRP A 62  ? 0.20639 0.24973 0.12189 0.04455  -0.00470 -0.02852 1068 TRP A CZ3 
487  C CH2 . TRP A 62  ? 0.20781 0.26409 0.13392 0.05205  0.00080  -0.01932 1068 TRP A CH2 
488  N N   . GLU A 63  ? 0.11067 0.16572 0.06311 -0.01542 -0.00360 0.02017  1069 GLU A N   
489  C CA  . GLU A 63  ? 0.11747 0.15379 0.07287 -0.02339 -0.00841 0.01607  1069 GLU A CA  
490  C C   . GLU A 63  ? 0.11090 0.17300 0.06583 -0.02714 -0.00161 0.03139  1069 GLU A C   
491  O O   . GLU A 63  ? 0.11757 0.19256 0.06501 -0.01856 -0.00235 0.01318  1069 GLU A O   
492  C CB  . GLU A 63  ? 0.12728 0.16735 0.08360 -0.01633 -0.01769 0.02636  1069 GLU A CB  
493  C CG  . GLU A 63  ? 0.11947 0.16673 0.08503 -0.01212 -0.01085 0.01394  1069 GLU A CG  
494  C CD  . GLU A 63  ? 0.10413 0.17860 0.07045 -0.02699 -0.00261 0.01298  1069 GLU A CD  
495  O OE1 . GLU A 63  ? 0.12335 0.17176 0.09224 -0.01579 -0.00254 0.00061  1069 GLU A OE1 
496  O OE2 . GLU A 63  ? 0.12293 0.23307 0.06855 -0.04412 -0.00477 0.01313  1069 GLU A OE2 
497  N N   . GLY A 64  ? 0.10078 0.18073 0.07463 -0.01868 -0.00982 0.02287  1070 GLY A N   
498  C CA  . GLY A 64  ? 0.11115 0.19694 0.07530 -0.02377 -0.00781 0.02549  1070 GLY A CA  
499  C C   . GLY A 64  ? 0.11503 0.17778 0.06967 -0.01753 0.00287  0.01184  1070 GLY A C   
500  O O   . GLY A 64  ? 0.11904 0.21384 0.07986 -0.03765 -0.00814 0.02910  1070 GLY A O   
501  N N   . GLN A 65  ? 0.12375 0.16789 0.06343 -0.01656 0.00950  0.01788  1071 GLN A N   
502  C CA  . GLN A 65  ? 0.11673 0.17883 0.07023 -0.01887 0.00763  0.01770  1071 GLN A CA  
503  C C   . GLN A 65  ? 0.11288 0.17363 0.07453 -0.00375 0.00782  0.01916  1071 GLN A C   
504  O O   . GLN A 65  ? 0.11052 0.18674 0.08112 -0.01664 0.01446  0.01404  1071 GLN A O   
505  C CB  . GLN A 65  ? 0.11821 0.17751 0.06732 0.00137  -0.00019 0.00644  1071 GLN A CB  
506  C CG  . GLN A 65  ? 0.12058 0.17358 0.06882 -0.00610 0.00044  0.01198  1071 GLN A CG  
507  C CD  . GLN A 65  ? 0.11131 0.18175 0.07291 -0.01652 0.00906  0.01229  1071 GLN A CD  
508  O OE1 . GLN A 65  ? 0.12948 0.18786 0.08234 -0.02510 -0.00622 0.01197  1071 GLN A OE1 
509  N NE2 . GLN A 65  ? 0.14375 0.17016 0.08348 -0.01333 -0.00771 -0.00988 1071 GLN A NE2 
510  N N   . SER A 66  ? 0.10823 0.19127 0.07532 -0.02660 0.00922  0.02751  1072 SER A N   
511  C CA  . SER A 66  ? 0.10211 0.20239 0.08107 -0.02437 0.00037  0.03231  1072 SER A CA  
512  C C   . SER A 66  ? 0.10623 0.17411 0.07696 -0.02445 0.00599  0.01124  1072 SER A C   
513  O O   . SER A 66  ? 0.13408 0.19123 0.07573 -0.00674 0.01503  0.01271  1072 SER A O   
514  C CB  . SER A 66  ? 0.12831 0.25044 0.09502 -0.02219 -0.00988 0.06278  1072 SER A CB  
515  O OG  . SER A 66  ? 0.14512 0.31514 0.12114 -0.02088 -0.01918 0.07232  1072 SER A OG  
516  N N   . TYR A 67  ? 0.11642 0.17143 0.07455 -0.01613 0.00321  0.00044  1073 TYR A N   
517  C CA  . TYR A 67  ? 0.10670 0.17956 0.07303 -0.02480 -0.00189 0.01725  1073 TYR A CA  
518  C C   . TYR A 67  ? 0.11094 0.18750 0.07434 -0.01835 -0.00464 0.01407  1073 TYR A C   
519  O O   . TYR A 67  ? 0.11457 0.20741 0.08787 -0.02675 -0.00313 0.01923  1073 TYR A O   
520  C CB  . TYR A 67  ? 0.11692 0.19752 0.08393 -0.01198 -0.00958 0.00897  1073 TYR A CB  
521  C CG  . TYR A 67  ? 0.11140 0.17737 0.07776 -0.01073 -0.00323 0.01623  1073 TYR A CG  
522  C CD1 . TYR A 67  ? 0.11796 0.18740 0.07923 -0.00158 -0.00048 0.01808  1073 TYR A CD1 
523  C CD2 . TYR A 67  ? 0.13212 0.16915 0.08684 -0.01596 -0.01294 -0.00162 1073 TYR A CD2 
524  C CE1 . TYR A 67  ? 0.12410 0.18024 0.08198 -0.01360 -0.00344 0.01181  1073 TYR A CE1 
525  C CE2 . TYR A 67  ? 0.14073 0.18455 0.08791 0.00306  -0.01010 0.01651  1073 TYR A CE2 
526  C CZ  . TYR A 67  ? 0.11232 0.17923 0.07806 -0.01728 -0.00480 0.01540  1073 TYR A CZ  
527  O OH  . TYR A 67  ? 0.12054 0.18231 0.07465 -0.01951 -0.00718 0.01872  1073 TYR A OH  
528  N N   . GLY A 68  ? 0.11950 0.18866 0.07132 -0.03418 0.00252  0.01450  1074 GLY A N   
529  C CA  . GLY A 68  ? 0.12293 0.21552 0.07021 -0.03466 0.00803  0.00303  1074 GLY A CA  
530  C C   . GLY A 68  ? 0.11497 0.20596 0.07162 -0.03391 0.00415  0.01109  1074 GLY A C   
531  O O   . GLY A 68  ? 0.11517 0.20992 0.07364 -0.02674 0.00869  0.00899  1074 GLY A O   
532  N N   . VAL A 69  ? 0.12107 0.20502 0.07460 -0.03111 0.00309  0.01947  1075 VAL A N   
533  C CA  . VAL A 69  ? 0.12836 0.22066 0.07395 -0.04119 0.00293  0.00947  1075 VAL A CA  
534  C C   . VAL A 69  ? 0.11251 0.21957 0.06574 -0.04060 0.00218  0.00905  1075 VAL A C   
535  O O   . VAL A 69  ? 0.12645 0.24187 0.06967 -0.04942 -0.00444 0.01817  1075 VAL A O   
536  C CB  . VAL A 69  ? 0.12096 0.21605 0.08857 -0.03299 0.00149  0.01079  1075 VAL A CB  
537  C CG1 . VAL A 69  ? 0.13023 0.22546 0.09238 -0.01295 -0.00189 0.00390  1075 VAL A CG1 
538  C CG2 . VAL A 69  ? 0.14255 0.21190 0.10290 -0.01566 -0.00166 0.00810  1075 VAL A CG2 
539  N N   . ILE A 70  ? 0.11268 0.22262 0.06918 -0.04042 0.00235  0.00217  1076 ILE A N   
540  C CA  . ILE A 70  ? 0.12186 0.21539 0.08195 -0.02777 0.00726  -0.00002 1076 ILE A CA  
541  C C   . ILE A 70  ? 0.11128 0.22804 0.07859 -0.03023 0.01086  0.01310  1076 ILE A C   
542  O O   . ILE A 70  ? 0.13011 0.22186 0.07008 -0.01898 0.00813  0.01474  1076 ILE A O   
543  C CB  . ILE A 70  ? 0.14325 0.22299 0.10799 -0.02911 0.02827  0.00369  1076 ILE A CB  
544  C CG1 . ILE A 70  ? 0.16505 0.23869 0.12874 -0.03206 0.03392  -0.00485 1076 ILE A CG1 
545  C CG2 . ILE A 70  ? 0.15929 0.22769 0.11736 -0.04376 0.03589  0.00095  1076 ILE A CG2 
546  C CD1 . ILE A 70  ? 0.21537 0.26731 0.14457 0.00158  0.03771  0.01267  1076 ILE A CD1 
547  N N   . PRO A 71  ? 0.12252 0.23619 0.08280 -0.02891 0.00859  0.01903  1077 PRO A N   
548  C CA  . PRO A 71  ? 0.12696 0.23506 0.09121 -0.01971 0.01288  0.01003  1077 PRO A CA  
549  C C   . PRO A 71  ? 0.12436 0.22295 0.09509 -0.02014 0.02194  0.01105  1077 PRO A C   
550  O O   . PRO A 71  ? 0.13703 0.22446 0.09386 -0.02463 0.01916  0.01519  1077 PRO A O   
551  C CB  . PRO A 71  ? 0.13229 0.25786 0.09176 -0.01369 0.00257  0.01876  1077 PRO A CB  
552  C CG  . PRO A 71  ? 0.13878 0.25454 0.09036 -0.02412 0.00008  0.02674  1077 PRO A CG  
553  C CD  . PRO A 71  ? 0.12200 0.25826 0.08509 -0.02939 -0.00079 0.02514  1077 PRO A CD  
554  N N   . PRO A 72  ? 0.13033 0.22602 0.09962 -0.01387 0.02731  0.01817  1078 PRO A N   
555  C CA  A PRO A 72  ? 0.14029 0.23441 0.10036 -0.02396 0.02415  0.01383  1078 PRO A CA  
556  C CA  B PRO A 72  ? 0.13923 0.23005 0.10086 -0.01825 0.02640  0.01396  1078 PRO A CA  
557  C C   . PRO A 72  ? 0.15301 0.24085 0.10501 -0.02420 0.02772  0.00702  1078 PRO A C   
558  O O   . PRO A 72  ? 0.15925 0.24504 0.11435 -0.00240 0.01226  0.00512  1078 PRO A O   
559  C CB  A PRO A 72  ? 0.16004 0.23995 0.10155 -0.01157 0.02023  0.01310  1078 PRO A CB  
560  C CB  B PRO A 72  ? 0.15737 0.23616 0.10380 -0.00291 0.02843  0.01251  1078 PRO A CB  
561  C CG  A PRO A 72  ? 0.16440 0.22467 0.10169 -0.00104 0.01839  0.01493  1078 PRO A CG  
562  C CG  B PRO A 72  ? 0.13662 0.23333 0.10496 0.00728  0.02611  0.01676  1078 PRO A CG  
563  C CD  A PRO A 72  ? 0.15396 0.21444 0.10065 -0.00744 0.01855  0.01514  1078 PRO A CD  
564  C CD  B PRO A 72  ? 0.13201 0.22194 0.10314 0.00627  0.02192  0.01405  1078 PRO A CD  
565  N N   . GLY A 73  ? 0.17306 0.27050 0.11664 -0.05575 0.03966  0.00209  1079 GLY A N   
566  C CA  . GLY A 73  ? 0.18163 0.28981 0.13713 -0.07111 0.04010  -0.01934 1079 GLY A CA  
567  C C   . GLY A 73  ? 0.20201 0.29276 0.14735 -0.07206 0.04873  -0.03157 1079 GLY A C   
568  O O   . GLY A 73  ? 0.21037 0.26899 0.15651 -0.03660 0.04942  -0.01477 1079 GLY A O   
569  N N   . GLU A 74  ? 0.23662 0.32889 0.15583 -0.09937 0.05202  -0.06776 1080 GLU A N   
570  C CA  . GLU A 74  ? 0.30216 0.38594 0.17422 -0.14693 0.05759  -0.07560 1080 GLU A CA  
571  C C   . GLU A 74  ? 0.31407 0.39166 0.17962 -0.16690 0.06669  -0.09282 1080 GLU A C   
572  O O   . GLU A 74  ? 0.33328 0.39690 0.17333 -0.13814 0.06612  -0.07272 1080 GLU A O   
573  C CB  . GLU A 74  ? 0.37067 0.43339 0.19364 -0.16090 0.05506  -0.04472 1080 GLU A CB  
574  C CG  . GLU A 74  ? 0.43053 0.52783 0.21726 -0.13668 0.06327  -0.00601 1080 GLU A CG  
575  C CD  . GLU A 74  ? 0.47298 0.61350 0.23878 -0.12537 0.07040  0.01936  1080 GLU A CD  
576  O OE1 . GLU A 74  ? 0.48426 0.63876 0.24734 -0.13347 0.07139  0.02443  1080 GLU A OE1 
577  O OE2 . GLU A 74  ? 0.50416 0.67433 0.24786 -0.06912 0.06846  0.02328  1080 GLU A OE2 
578  N N   . ASN A 75  ? 0.32102 0.41381 0.19590 -0.19773 0.07053  -0.09869 1081 ASN A N   
579  C CA  . ASN A 75  ? 0.33707 0.44670 0.22306 -0.19970 0.07417  -0.08551 1081 ASN A CA  
580  C C   . ASN A 75  ? 0.32703 0.47027 0.25666 -0.22448 0.04953  -0.06028 1081 ASN A C   
581  O O   . ASN A 75  ? 0.32717 0.48112 0.25343 -0.22616 0.04914  -0.06441 1081 ASN A O   
582  C CB  . ASN A 75  ? 0.38198 0.46211 0.22510 -0.17389 0.08989  -0.07700 1081 ASN A CB  
583  C CG  . ASN A 75  ? 0.44014 0.50381 0.23161 -0.11999 0.09395  -0.06454 1081 ASN A CG  
584  O OD1 . ASN A 75  ? 0.44643 0.48386 0.23230 -0.16346 0.07741  -0.06833 1081 ASN A OD1 
585  N ND2 . ASN A 75  ? 0.47031 0.56107 0.23713 -0.06255 0.10759  -0.06322 1081 ASN A ND2 
586  N N   . PRO A 76  ? 0.31900 0.51061 0.29956 -0.22508 0.01486  -0.05693 1082 PRO A N   
587  C CA  . PRO A 76  ? 0.33606 0.52135 0.33157 -0.22694 -0.01021 -0.06514 1082 PRO A CA  
588  C C   . PRO A 76  ? 0.35742 0.52317 0.36734 -0.23644 -0.02643 -0.05808 1082 PRO A C   
589  O O   . PRO A 76  ? 0.34910 0.56585 0.36876 -0.23474 -0.03174 -0.04897 1082 PRO A O   
590  C CB  . PRO A 76  ? 0.32999 0.55552 0.32800 -0.21241 -0.00903 -0.05747 1082 PRO A CB  
591  C CG  . PRO A 76  ? 0.33103 0.56038 0.32082 -0.19033 -0.00123 -0.05179 1082 PRO A CG  
592  C CD  . PRO A 76  ? 0.31758 0.54142 0.31081 -0.21002 0.00697  -0.05472 1082 PRO A CD  
593  N N   . LYS A 77  ? 0.39238 0.50824 0.39398 -0.23432 -0.04872 -0.07891 1083 LYS A N   
594  C CA  . LYS A 77  ? 0.43645 0.49591 0.42003 -0.22166 -0.06601 -0.08699 1083 LYS A CA  
595  C C   . LYS A 77  ? 0.48293 0.54189 0.43172 -0.19471 -0.07277 -0.08772 1083 LYS A C   
596  O O   . LYS A 77  ? 0.50136 0.56478 0.43322 -0.17413 -0.07933 -0.09703 1083 LYS A O   
602  N N   . LYS A 78  ? 0.49711 0.55181 0.44110 -0.20679 -0.06841 -0.07211 1084 LYS A N   
603  C CA  . LYS A 78  ? 0.49799 0.55079 0.45164 -0.22703 -0.05230 -0.04379 1084 LYS A CA  
604  C C   . LYS A 78  ? 0.52217 0.62336 0.44500 -0.24498 -0.02729 -0.00503 1084 LYS A C   
605  O O   . LYS A 78  ? 0.52290 0.63879 0.44604 -0.25769 -0.02325 -0.00258 1084 LYS A O   
611  N N   . PRO A 79  ? 0.53629 0.67354 0.43682 -0.26221 -0.00670 0.02826  1085 PRO A N   
612  C CA  . PRO A 79  ? 0.54366 0.67288 0.42862 -0.26802 0.01009  0.05169  1085 PRO A CA  
613  C C   . PRO A 79  ? 0.55386 0.63265 0.41590 -0.26369 0.02758  0.07292  1085 PRO A C   
614  O O   . PRO A 79  ? 0.56204 0.61913 0.41903 -0.26074 0.02279  0.07083  1085 PRO A O   
615  C CB  . PRO A 79  ? 0.54763 0.71395 0.43185 -0.25909 0.00800  0.04990  1085 PRO A CB  
616  C CG  . PRO A 79  ? 0.54845 0.72708 0.43447 -0.26059 0.00436  0.04645  1085 PRO A CG  
617  C CD  . PRO A 79  ? 0.54554 0.71402 0.43601 -0.25804 -0.00017 0.04053  1085 PRO A CD  
618  N N   . GLY A 80  ? 0.54960 0.59744 0.39927 -0.26426 0.04619  0.08967  1086 GLY A N   
619  C CA  . GLY A 80  ? 0.55381 0.57742 0.38284 -0.22638 0.05750  0.09361  1086 GLY A CA  
620  C C   . GLY A 80  ? 0.55764 0.55207 0.36464 -0.18257 0.06168  0.09048  1086 GLY A C   
621  O O   . GLY A 80  ? 0.57824 0.59095 0.36901 -0.14441 0.05670  0.09016  1086 GLY A O   
622  N N   . ALA A 81  ? 0.53826 0.47002 0.34117 -0.17984 0.06697  0.07818  1087 ALA A N   
623  C CA  . ALA A 81  ? 0.51536 0.41206 0.31604 -0.15696 0.06385  0.04911  1087 ALA A CA  
624  C C   . ALA A 81  ? 0.47837 0.35527 0.28776 -0.14360 0.06181  0.03313  1087 ALA A C   
625  O O   . ALA A 81  ? 0.47156 0.34701 0.28382 -0.15668 0.07307  0.03312  1087 ALA A O   
626  C CB  . ALA A 81  ? 0.52783 0.42069 0.31837 -0.12857 0.06086  0.03700  1087 ALA A CB  
627  N N   . PRO A 82  ? 0.43954 0.31295 0.26194 -0.13349 0.05395  0.01928  1088 PRO A N   
628  C CA  . PRO A 82  ? 0.40776 0.31802 0.23661 -0.09749 0.04328  0.00781  1088 PRO A CA  
629  C C   . PRO A 82  ? 0.33495 0.30044 0.19618 -0.11656 0.03527  -0.00666 1088 PRO A C   
630  O O   . PRO A 82  ? 0.34235 0.32099 0.19564 -0.12449 0.02421  -0.01977 1088 PRO A O   
631  C CB  . PRO A 82  ? 0.43237 0.33916 0.24798 -0.08037 0.04530  0.01149  1088 PRO A CB  
632  C CG  . PRO A 82  ? 0.44202 0.36164 0.25699 -0.08468 0.05135  0.01290  1088 PRO A CG  
633  C CD  . PRO A 82  ? 0.44777 0.33872 0.26167 -0.10148 0.05104  0.00949  1088 PRO A CD  
634  N N   . GLN A 83  ? 0.26644 0.27507 0.16511 -0.10225 0.03278  0.00975  1089 GLN A N   
635  C CA  . GLN A 83  ? 0.20963 0.28425 0.13939 -0.07895 0.02204  0.00988  1089 GLN A CA  
636  C C   . GLN A 83  ? 0.19764 0.28067 0.12983 -0.08209 0.00901  0.00411  1089 GLN A C   
637  O O   . GLN A 83  ? 0.19998 0.29072 0.13938 -0.06201 0.01192  -0.00086 1089 GLN A O   
638  C CB  . GLN A 83  ? 0.16401 0.29492 0.13652 -0.07391 0.02131  0.01120  1089 GLN A CB  
639  C CG  . GLN A 83  ? 0.17953 0.28352 0.13726 -0.04327 0.01267  0.01052  1089 GLN A CG  
640  C CD  . GLN A 83  ? 0.17451 0.28396 0.13125 -0.04593 0.00761  -0.00097 1089 GLN A CD  
641  O OE1 . GLN A 83  ? 0.17073 0.31793 0.12678 -0.05066 -0.00023 -0.00430 1089 GLN A OE1 
642  N NE2 . GLN A 83  ? 0.19421 0.26178 0.13665 -0.04644 0.01190  -0.00320 1089 GLN A NE2 
643  N N   . ASN A 84  ? 0.18364 0.27708 0.11777 -0.09881 0.00641  0.00202  1090 ASN A N   
644  C CA  . ASN A 84  ? 0.17723 0.29067 0.11699 -0.09357 -0.01045 -0.00640 1090 ASN A CA  
645  C C   . ASN A 84  ? 0.16301 0.26296 0.10411 -0.05563 -0.00874 -0.00542 1090 ASN A C   
646  O O   . ASN A 84  ? 0.12914 0.26937 0.10167 -0.05707 0.00413  0.01298  1090 ASN A O   
647  C CB  . ASN A 84  ? 0.18753 0.35192 0.13621 -0.11249 -0.01796 -0.01435 1090 ASN A CB  
648  C CG  . ASN A 84  ? 0.24643 0.39706 0.15498 -0.09370 -0.01570 -0.02688 1090 ASN A CG  
649  O OD1 . ASN A 84  ? 0.28837 0.36367 0.16580 -0.11355 0.00016  -0.03345 1090 ASN A OD1 
650  N ND2 . ASN A 84  ? 0.24419 0.44038 0.16346 -0.10117 -0.02558 -0.04015 1090 ASN A ND2 
651  N N   . VAL A 85  ? 0.16178 0.25303 0.09973 -0.06369 0.00257  -0.00244 1091 VAL A N   
652  C CA  . VAL A 85  ? 0.13994 0.24010 0.09716 -0.07016 -0.00052 -0.00204 1091 VAL A CA  
653  C C   . VAL A 85  ? 0.14430 0.24760 0.08663 -0.05827 -0.00635 -0.00239 1091 VAL A C   
654  O O   . VAL A 85  ? 0.16750 0.26473 0.09131 -0.06416 -0.02779 -0.01104 1091 VAL A O   
655  C CB  . VAL A 85  ? 0.15841 0.22965 0.10857 -0.05423 0.00532  -0.00778 1091 VAL A CB  
656  C CG1 . VAL A 85  ? 0.16818 0.22442 0.12005 -0.04032 0.02031  -0.01022 1091 VAL A CG1 
657  C CG2 . VAL A 85  ? 0.20154 0.24940 0.11617 -0.02229 0.01631  0.00635  1091 VAL A CG2 
658  N N   . ARG A 86  ? 0.12284 0.22679 0.07588 -0.04335 0.00150  0.00947  1092 ARG A N   
659  C CA  . ARG A 86  ? 0.11670 0.23626 0.07184 -0.04471 -0.00672 0.00866  1092 ARG A CA  
660  C C   . ARG A 86  ? 0.11280 0.22179 0.06827 -0.03997 -0.00054 0.01602  1092 ARG A C   
661  O O   . ARG A 86  ? 0.11578 0.24632 0.06609 -0.03528 -0.00483 0.01639  1092 ARG A O   
662  C CB  . ARG A 86  ? 0.12011 0.24677 0.07728 -0.04365 -0.00647 0.01584  1092 ARG A CB  
663  C CG  . ARG A 86  ? 0.12845 0.25964 0.08711 -0.03099 0.01219  0.02965  1092 ARG A CG  
664  C CD  . ARG A 86  ? 0.11118 0.28437 0.09237 -0.03511 0.00544  0.02977  1092 ARG A CD  
665  N NE  . ARG A 86  ? 0.11387 0.31011 0.09721 -0.05081 0.00443  0.02437  1092 ARG A NE  
666  C CZ  . ARG A 86  ? 0.12051 0.30260 0.10717 -0.04013 -0.00081 0.03312  1092 ARG A CZ  
667  N NH1 . ARG A 86  ? 0.13528 0.30548 0.11126 -0.04296 0.00480  0.03234  1092 ARG A NH1 
668  N NH2 . ARG A 86  ? 0.12023 0.32695 0.12245 -0.03160 -0.00494 0.03200  1092 ARG A NH2 
669  N N   . LEU A 87  ? 0.11806 0.22426 0.06853 -0.04010 0.00470  0.01001  1093 LEU A N   
670  C CA  . LEU A 87  ? 0.12524 0.21075 0.06873 -0.03608 0.00771  0.00662  1093 LEU A CA  
671  C C   . LEU A 87  ? 0.10645 0.20177 0.07234 -0.02824 -0.00192 0.00393  1093 LEU A C   
672  O O   . LEU A 87  ? 0.10857 0.22256 0.07504 -0.01900 -0.00381 0.00929  1093 LEU A O   
673  C CB  . LEU A 87  ? 0.13833 0.23254 0.07773 -0.04486 0.01965  0.00400  1093 LEU A CB  
674  C CG  . LEU A 87  ? 0.19157 0.21542 0.08771 -0.03408 0.00991  -0.02048 1093 LEU A CG  
675  C CD1 . LEU A 87  ? 0.26140 0.24963 0.09513 -0.00582 0.00611  -0.02968 1093 LEU A CD1 
676  C CD2 . LEU A 87  ? 0.20926 0.23578 0.10136 -0.00880 -0.00001 -0.01488 1093 LEU A CD2 
677  N N   . TYR A 88  ? 0.10890 0.18513 0.08080 -0.01700 -0.00318 0.01164  1094 TYR A N   
678  C CA  . TYR A 88  ? 0.11425 0.19029 0.08456 -0.02381 -0.00322 0.01503  1094 TYR A CA  
679  C C   . TYR A 88  ? 0.11124 0.18073 0.08733 -0.01982 -0.00077 0.01738  1094 TYR A C   
680  O O   . TYR A 88  ? 0.11003 0.20355 0.10141 -0.01207 0.00091  0.03198  1094 TYR A O   
681  C CB  . TYR A 88  ? 0.10658 0.21345 0.07490 -0.00710 -0.01081 0.01207  1094 TYR A CB  
682  C CG  . TYR A 88  ? 0.11561 0.21122 0.06880 -0.01937 -0.01238 0.01352  1094 TYR A CG  
683  C CD1 . TYR A 88  ? 0.10848 0.20748 0.07009 -0.01636 -0.01011 0.01232  1094 TYR A CD1 
684  C CD2 . TYR A 88  ? 0.12847 0.20360 0.06211 -0.02014 -0.00966 0.01393  1094 TYR A CD2 
685  C CE1 . TYR A 88  ? 0.11984 0.22824 0.06861 -0.02619 -0.00310 0.01694  1094 TYR A CE1 
686  C CE2 . TYR A 88  ? 0.11591 0.23403 0.06511 -0.03067 -0.00559 0.02446  1094 TYR A CE2 
687  C CZ  . TYR A 88  ? 0.10718 0.23977 0.07141 -0.02413 -0.00231 0.02711  1094 TYR A CZ  
688  O OH  . TYR A 88  ? 0.10905 0.25743 0.08949 -0.02092 0.00394  0.03767  1094 TYR A OH  
689  N N   . SER A 89  ? 0.10231 0.20001 0.08825 -0.02215 -0.00301 0.02167  1095 SER A N   
690  C CA  . SER A 89  ? 0.10556 0.20461 0.09474 -0.02812 -0.00285 0.03294  1095 SER A CA  
691  C C   . SER A 89  ? 0.09014 0.19183 0.09657 -0.01647 -0.01050 0.02191  1095 SER A C   
692  O O   . SER A 89  ? 0.11199 0.21009 0.12004 0.00188  -0.02556 -0.01766 1095 SER A O   
693  C CB  . SER A 89  ? 0.12214 0.23839 0.10038 -0.04229 -0.01983 0.04476  1095 SER A CB  
694  O OG  . SER A 89  ? 0.18467 0.25831 0.10002 -0.01380 -0.02066 0.04019  1095 SER A OG  
695  N N   . ILE A 90  ? 0.09361 0.18992 0.08483 -0.01984 -0.00837 0.02657  1096 ILE A N   
696  C CA  . ILE A 90  ? 0.09538 0.19772 0.07894 -0.01527 -0.00267 0.01980  1096 ILE A CA  
697  C C   . ILE A 90  ? 0.09546 0.17357 0.07289 -0.00750 0.00070  0.01556  1096 ILE A C   
698  O O   . ILE A 90  ? 0.10518 0.17483 0.07451 -0.01099 0.00405  0.01291  1096 ILE A O   
699  C CB  . ILE A 90  ? 0.09994 0.17116 0.08495 -0.01009 -0.00586 0.02707  1096 ILE A CB  
700  C CG1 . ILE A 90  ? 0.11385 0.17375 0.08922 -0.02245 -0.01567 0.02789  1096 ILE A CG1 
701  C CG2 . ILE A 90  ? 0.10761 0.17137 0.09168 -0.00966 -0.01522 0.01782  1096 ILE A CG2 
702  C CD1 . ILE A 90  ? 0.11507 0.16990 0.09671 -0.01597 -0.00216 0.03318  1096 ILE A CD1 
703  N N   . ALA A 91  ? 0.10041 0.16980 0.06887 -0.00996 -0.00681 0.01103  1097 ALA A N   
704  C CA  . ALA A 91  ? 0.10518 0.16911 0.08010 0.00107  -0.00925 0.00812  1097 ALA A CA  
705  C C   . ALA A 91  ? 0.10103 0.15134 0.07727 -0.01336 -0.00594 0.02126  1097 ALA A C   
706  O O   . ALA A 91  ? 0.11468 0.17561 0.07677 0.00117  -0.02141 0.01427  1097 ALA A O   
707  C CB  . ALA A 91  ? 0.10790 0.18639 0.08356 0.01591  -0.00685 0.00573  1097 ALA A CB  
708  N N   . SER A 92  ? 0.10349 0.15821 0.07378 0.00766  -0.01217 0.01371  1098 SER A N   
709  C CA  . SER A 92  ? 0.09292 0.16370 0.07254 0.00483  -0.01305 0.01303  1098 SER A CA  
710  C C   . SER A 92  ? 0.09900 0.13053 0.06912 -0.01183 -0.00597 0.01125  1098 SER A C   
711  O O   . SER A 92  ? 0.10830 0.15964 0.06926 0.00137  -0.00481 0.00992  1098 SER A O   
712  C CB  . SER A 92  ? 0.09940 0.15893 0.07420 -0.00707 -0.00465 0.01803  1098 SER A CB  
713  O OG  . SER A 92  ? 0.10087 0.16038 0.07202 -0.01021 0.00022  0.01183  1098 SER A OG  
714  N N   . THR A 93  ? 0.09230 0.14647 0.06717 -0.00073 -0.00696 0.01453  1099 THR A N   
715  C CA  . THR A 93  ? 0.09892 0.14730 0.06869 -0.00785 -0.00151 0.00972  1099 THR A CA  
716  C C   . THR A 93  ? 0.08817 0.15750 0.06135 -0.00893 -0.00204 0.00350  1099 THR A C   
717  O O   . THR A 93  ? 0.09596 0.15167 0.05976 -0.00997 0.00533  0.01094  1099 THR A O   
718  C CB  . THR A 93  ? 0.10973 0.15887 0.06484 0.00120  -0.01013 0.01520  1099 THR A CB  
719  O OG1 . THR A 93  ? 0.10227 0.15626 0.06636 -0.00333 -0.01273 0.02037  1099 THR A OG1 
720  C CG2 . THR A 93  ? 0.11489 0.15458 0.07685 -0.01277 -0.00196 0.02507  1099 THR A CG2 
721  N N   . ARG A 94  ? 0.09177 0.14990 0.06234 -0.00732 -0.00449 0.00584  1100 ARG A N   
722  C CA  . ARG A 94  ? 0.11069 0.14922 0.06585 0.00220  -0.00385 0.00147  1100 ARG A CA  
723  C C   . ARG A 94  ? 0.09680 0.14901 0.06607 -0.00569 0.00305  0.01278  1100 ARG A C   
724  O O   . ARG A 94  ? 0.10187 0.15592 0.06795 -0.00563 0.00270  0.01250  1100 ARG A O   
725  C CB  . ARG A 94  ? 0.11118 0.15610 0.08109 -0.01021 0.00738  0.00392  1100 ARG A CB  
726  C CG  . ARG A 94  ? 0.10657 0.17002 0.09178 0.01273  0.00278  0.00045  1100 ARG A CG  
727  C CD  . ARG A 94  ? 0.10659 0.18818 0.08607 -0.00369 -0.00153 0.00611  1100 ARG A CD  
728  N NE  . ARG A 94  ? 0.10821 0.19524 0.08637 0.00170  0.00879  0.00843  1100 ARG A NE  
729  C CZ  . ARG A 94  ? 0.11265 0.21725 0.09030 0.00178  0.00124  0.01331  1100 ARG A CZ  
730  N NH1 . ARG A 94  ? 0.12731 0.22199 0.09853 0.02958  -0.00768 -0.00625 1100 ARG A NH1 
731  N NH2 . ARG A 94  ? 0.13320 0.26690 0.08705 0.00678  -0.00455 0.02059  1100 ARG A NH2 
732  N N   . TYR A 95  ? 0.10115 0.14794 0.06363 -0.00326 -0.00141 0.01175  1101 TYR A N   
733  C CA  . TYR A 95  ? 0.10001 0.15528 0.06475 -0.00458 -0.00623 0.01085  1101 TYR A CA  
734  C C   . TYR A 95  ? 0.09548 0.16127 0.06637 -0.00492 -0.00622 0.01381  1101 TYR A C   
735  O O   . TYR A 95  ? 0.10322 0.17371 0.06244 -0.00012 -0.00691 0.01637  1101 TYR A O   
736  C CB  . TYR A 95  ? 0.09677 0.16055 0.06965 -0.00536 -0.00754 0.00518  1101 TYR A CB  
737  C CG  . TYR A 95  ? 0.09996 0.16009 0.07079 -0.01578 -0.00839 0.00884  1101 TYR A CG  
738  C CD1 . TYR A 95  ? 0.10270 0.15718 0.07908 0.00685  -0.00598 0.01568  1101 TYR A CD1 
739  C CD2 . TYR A 95  ? 0.10340 0.15215 0.07720 -0.01123 -0.00398 0.00519  1101 TYR A CD2 
740  C CE1 . TYR A 95  ? 0.10651 0.17669 0.08382 0.01255  -0.01316 0.01751  1101 TYR A CE1 
741  C CE2 . TYR A 95  ? 0.10131 0.17127 0.08192 -0.00214 -0.00403 0.00978  1101 TYR A CE2 
742  C CZ  . TYR A 95  ? 0.09887 0.17510 0.08676 0.00603  -0.00541 0.00573  1101 TYR A CZ  
743  O OH  . TYR A 95  ? 0.12722 0.22404 0.09757 0.03563  -0.00710 -0.00025 1101 TYR A OH  
744  N N   . GLY A 96  ? 0.10380 0.16391 0.07086 0.01033  -0.01010 0.00268  1102 GLY A N   
745  C CA  . GLY A 96  ? 0.10124 0.17341 0.07068 0.00016  -0.00972 0.00147  1102 GLY A CA  
746  C C   . GLY A 96  ? 0.09788 0.14982 0.06288 -0.00608 -0.00585 0.00760  1102 GLY A C   
747  O O   . GLY A 96  ? 0.10946 0.16585 0.06256 0.00198  -0.00782 0.01468  1102 GLY A O   
748  N N   . ASP A 97  ? 0.10542 0.15107 0.07368 -0.00144 -0.00529 0.00400  1103 ASP A N   
749  C CA  . ASP A 97  ? 0.10455 0.16723 0.08199 0.01156  -0.01876 -0.00551 1103 ASP A CA  
750  C C   . ASP A 97  ? 0.11771 0.16708 0.08003 0.01781  -0.01922 -0.01355 1103 ASP A C   
751  O O   . ASP A 97  ? 0.13930 0.16894 0.09671 0.00825  -0.03348 -0.00930 1103 ASP A O   
752  C CB  . ASP A 97  ? 0.09429 0.17921 0.08647 0.01715  -0.02023 0.00325  1103 ASP A CB  
753  C CG  . ASP A 97  ? 0.09995 0.16845 0.08799 -0.00002 -0.01088 0.00119  1103 ASP A CG  
754  O OD1 . ASP A 97  ? 0.12226 0.17515 0.08609 0.01432  -0.01043 0.00000  1103 ASP A OD1 
755  O OD2 . ASP A 97  ? 0.10833 0.17978 0.09612 0.00990  -0.01103 0.00232  1103 ASP A OD2 
756  N N   A ASN A 98  ? 0.09735 0.19456 0.06558 0.02532  -0.00754 0.00284  1104 ASN A N   
757  N N   B ASN A 98  ? 0.12480 0.18993 0.07873 0.01950  -0.01425 -0.00113 1104 ASN A N   
758  C CA  A ASN A 98  ? 0.10255 0.20365 0.06383 0.01596  -0.01680 0.00012  1104 ASN A CA  
759  C CA  B ASN A 98  ? 0.13956 0.20628 0.08211 0.02600  -0.01318 0.00716  1104 ASN A CA  
760  C C   A ASN A 98  ? 0.11689 0.16375 0.06653 0.00019  -0.01532 -0.00131 1104 ASN A C   
761  C C   B ASN A 98  ? 0.12870 0.18972 0.07558 0.01599  -0.01073 0.00729  1104 ASN A C   
762  O O   A ASN A 98  ? 0.11773 0.19247 0.07660 -0.00225 -0.03168 -0.00666 1104 ASN A O   
763  O O   B ASN A 98  ? 0.13307 0.20508 0.07840 0.02622  -0.01243 0.00279  1104 ASN A O   
764  C CB  A ASN A 98  ? 0.12129 0.20820 0.06096 0.01240  -0.00711 0.00047  1104 ASN A CB  
765  C CB  B ASN A 98  ? 0.17446 0.22965 0.09323 0.04957  -0.00648 0.01517  1104 ASN A CB  
766  C CG  A ASN A 98  ? 0.15160 0.20980 0.07147 0.04089  -0.01656 -0.00889 1104 ASN A CG  
767  C CG  B ASN A 98  ? 0.21954 0.27180 0.10982 0.07012  -0.00586 0.02517  1104 ASN A CG  
768  O OD1 A ASN A 98  ? 0.16523 0.22465 0.07459 0.05874  -0.02342 -0.01239 1104 ASN A OD1 
769  O OD1 B ASN A 98  ? 0.22693 0.27412 0.11553 0.06676  -0.00797 0.02835  1104 ASN A OD1 
770  N ND2 A ASN A 98  ? 0.16999 0.20459 0.07838 0.02841  -0.00817 -0.00053 1104 ASN A ND2 
771  N ND2 B ASN A 98  ? 0.26035 0.32311 0.11772 0.08677  -0.00513 0.02024  1104 ASN A ND2 
772  N N   . PHE A 99  ? 0.10806 0.17187 0.07027 0.00226  -0.01168 0.01302  1105 PHE A N   
773  C CA  . PHE A 99  ? 0.10752 0.17122 0.08266 -0.00015 -0.01314 0.00572  1105 PHE A CA  
774  C C   . PHE A 99  ? 0.10200 0.18473 0.07953 -0.00092 -0.02380 0.00282  1105 PHE A C   
775  O O   . PHE A 99  ? 0.11133 0.17698 0.09737 -0.00532 -0.01144 0.00961  1105 PHE A O   
776  C CB  . PHE A 99  ? 0.12653 0.16861 0.10093 -0.00166 -0.01743 0.00829  1105 PHE A CB  
777  C CG  . PHE A 99  ? 0.11814 0.16083 0.11530 -0.00926 -0.02361 0.00500  1105 PHE A CG  
778  C CD1 . PHE A 99  ? 0.13853 0.16215 0.12422 0.00483  -0.03406 0.01523  1105 PHE A CD1 
779  C CD2 . PHE A 99  ? 0.15462 0.17073 0.13061 0.01131  -0.00594 0.00972  1105 PHE A CD2 
780  C CE1 . PHE A 99  ? 0.12506 0.17406 0.13827 -0.00611 -0.03637 0.01562  1105 PHE A CE1 
781  C CE2 . PHE A 99  ? 0.18432 0.18095 0.13847 0.01986  -0.00589 0.01075  1105 PHE A CE2 
782  C CZ  . PHE A 99  ? 0.14926 0.17324 0.13885 -0.01506 -0.02461 0.01703  1105 PHE A CZ  
783  N N   . ASP A 100 ? 0.11099 0.17053 0.06592 -0.00770 -0.01526 0.02125  1106 ASP A N   
784  C CA  . ASP A 100 ? 0.11367 0.17799 0.06392 -0.00061 -0.01611 0.01189  1106 ASP A CA  
785  C C   . ASP A 100 ? 0.09151 0.16781 0.06535 0.00311  -0.00938 0.01945  1106 ASP A C   
786  O O   . ASP A 100 ? 0.11419 0.18866 0.06876 0.00113  -0.01012 0.02328  1106 ASP A O   
787  C CB  . ASP A 100 ? 0.10833 0.20936 0.06524 0.00535  -0.00827 0.01369  1106 ASP A CB  
788  C CG  . ASP A 100 ? 0.11518 0.20015 0.06322 0.01299  -0.00701 0.00629  1106 ASP A CG  
789  O OD1 . ASP A 100 ? 0.10776 0.19590 0.06486 0.01687  -0.00952 0.00673  1106 ASP A OD1 
790  O OD2 . ASP A 100 ? 0.11777 0.23519 0.06621 0.01275  -0.00003 0.00888  1106 ASP A OD2 
791  N N   . GLY A 101 ? 0.09105 0.17557 0.06844 0.00364  -0.00195 0.01324  1107 GLY A N   
792  C CA  . GLY A 101 ? 0.11615 0.16056 0.07118 -0.00090 -0.00489 0.01247  1107 GLY A CA  
793  C C   . GLY A 101 ? 0.12072 0.16742 0.07386 -0.01094 -0.00864 0.01242  1107 GLY A C   
794  O O   . GLY A 101 ? 0.18687 0.17052 0.08067 -0.01734 0.00610  0.01795  1107 GLY A O   
795  N N   . ARG A 102 ? 0.09587 0.18460 0.07343 -0.00609 -0.01012 0.02824  1108 ARG A N   
796  C CA  . ARG A 102 ? 0.10130 0.22056 0.07331 -0.00979 -0.00455 0.04758  1108 ARG A CA  
797  C C   . ARG A 102 ? 0.09175 0.21547 0.07476 -0.01279 -0.00675 0.04838  1108 ARG A C   
798  O O   . ARG A 102 ? 0.10907 0.23535 0.09328 -0.01982 -0.00942 0.05393  1108 ARG A O   
799  C CB  . ARG A 102 ? 0.11282 0.26952 0.09035 -0.01638 -0.01993 0.04971  1108 ARG A CB  
800  C CG  . ARG A 102 ? 0.15365 0.29246 0.09846 -0.00540 -0.03270 0.04498  1108 ARG A CG  
801  C CD  . ARG A 102 ? 0.15716 0.33849 0.10552 -0.01923 -0.01884 0.04838  1108 ARG A CD  
802  N NE  . ARG A 102 ? 0.17878 0.37734 0.11563 0.00561  0.00357  0.04050  1108 ARG A NE  
803  C CZ  . ARG A 102 ? 0.21505 0.39612 0.11850 0.05375  0.00811  0.03008  1108 ARG A CZ  
804  N NH1 . ARG A 102 ? 0.25904 0.44463 0.12758 0.10967  0.00020  0.02632  1108 ARG A NH1 
805  N NH2 . ARG A 102 ? 0.24103 0.38463 0.11710 0.06504  0.00231  0.03702  1108 ARG A NH2 
806  N N   . THR A 103 ? 0.09624 0.19737 0.07279 -0.00080 -0.01551 0.02779  1109 THR A N   
807  C CA  . THR A 103 ? 0.10036 0.18539 0.07389 -0.00542 -0.00579 0.02405  1109 THR A CA  
808  C C   . THR A 103 ? 0.10162 0.17110 0.07029 0.00174  -0.00761 0.01943  1109 THR A C   
809  O O   . THR A 103 ? 0.08668 0.18246 0.07340 0.00102  0.00282  0.02466  1109 THR A O   
810  C CB  . THR A 103 ? 0.12026 0.19901 0.08102 -0.00070 -0.00354 0.01293  1109 THR A CB  
811  O OG1 . THR A 103 ? 0.11779 0.19205 0.09071 0.00614  -0.00775 0.00517  1109 THR A OG1 
812  C CG2 . THR A 103 ? 0.12974 0.23778 0.08193 -0.01710 -0.00638 -0.00134 1109 THR A CG2 
813  N N   . GLY A 104 ? 0.09867 0.17654 0.06568 0.00240  -0.00763 0.01672  1110 GLY A N   
814  C CA  . GLY A 104 ? 0.10854 0.18073 0.06700 0.01115  -0.00595 0.02245  1110 GLY A CA  
815  C C   . GLY A 104 ? 0.10233 0.16672 0.06555 0.00791  -0.00734 0.01310  1110 GLY A C   
816  O O   . GLY A 104 ? 0.11240 0.21889 0.07078 0.01608  0.00752  0.02773  1110 GLY A O   
817  N N   . SER A 105 ? 0.08376 0.17101 0.06342 -0.00288 -0.01098 0.01360  1111 SER A N   
818  C CA  . SER A 105 ? 0.09481 0.18822 0.06745 0.00272  -0.00867 0.01532  1111 SER A CA  
819  C C   . SER A 105 ? 0.09716 0.18390 0.06755 -0.00294 -0.00161 0.01846  1111 SER A C   
820  O O   . SER A 105 ? 0.10247 0.19399 0.06295 -0.00576 -0.00524 0.02092  1111 SER A O   
821  C CB  . SER A 105 ? 0.09918 0.18231 0.07830 0.00654  -0.01664 0.00609  1111 SER A CB  
822  O OG  . SER A 105 ? 0.09967 0.18753 0.08116 0.00720  -0.01360 0.00100  1111 SER A OG  
823  N N   . LEU A 106 ? 0.09035 0.18054 0.07214 -0.00021 -0.00541 0.00949  1112 LEU A N   
824  C CA  . LEU A 106 ? 0.09487 0.18532 0.07380 0.00252  -0.00546 0.01528  1112 LEU A CA  
825  C C   . LEU A 106 ? 0.09845 0.19132 0.06831 0.00663  -0.00857 0.00720  1112 LEU A C   
826  O O   . LEU A 106 ? 0.12091 0.18990 0.07202 0.01223  -0.01612 0.01573  1112 LEU A O   
827  C CB  . LEU A 106 ? 0.09593 0.18158 0.08628 0.00601  -0.01245 0.01688  1112 LEU A CB  
828  C CG  . LEU A 106 ? 0.10445 0.19903 0.09155 -0.01704 -0.01150 0.02114  1112 LEU A CG  
829  C CD1 . LEU A 106 ? 0.12469 0.20209 0.09452 -0.02588 -0.00693 0.02321  1112 LEU A CD1 
830  C CD2 . LEU A 106 ? 0.12016 0.18974 0.09697 -0.00604 0.00154  0.00598  1112 LEU A CD2 
831  N N   . CYS A 107 ? 0.09361 0.18973 0.06708 0.00587  -0.00537 0.01584  1113 CYS A N   
832  C CA  . CYS A 107 ? 0.10217 0.19428 0.07571 0.00362  -0.00807 0.02706  1113 CYS A CA  
833  C C   . CYS A 107 ? 0.09526 0.20336 0.07549 0.00067  -0.00212 0.02368  1113 CYS A C   
834  O O   . CYS A 107 ? 0.10382 0.21123 0.07577 -0.00074 -0.00666 0.01370  1113 CYS A O   
835  C CB  . CYS A 107 ? 0.10971 0.19590 0.08174 0.00409  0.00175  0.02520  1113 CYS A CB  
836  S SG  . CYS A 107 ? 0.11895 0.20497 0.07827 0.01028  -0.00285 0.02397  1113 CYS A SG  
837  N N   . VAL A 108 ? 0.09437 0.21645 0.08125 0.00704  0.00484  0.03264  1114 VAL A N   
838  C CA  . VAL A 108 ? 0.08540 0.20965 0.09061 -0.00642 0.00115  0.03473  1114 VAL A CA  
839  C C   . VAL A 108 ? 0.09263 0.21851 0.09529 -0.00175 0.00469  0.03186  1114 VAL A C   
840  O O   . VAL A 108 ? 0.09927 0.22928 0.10196 0.01502  0.00208  0.02112  1114 VAL A O   
841  C CB  . VAL A 108 ? 0.09553 0.20563 0.10213 -0.00717 -0.00101 0.02958  1114 VAL A CB  
842  C CG1 . VAL A 108 ? 0.11672 0.21333 0.10754 0.00252  0.00874  0.02266  1114 VAL A CG1 
843  C CG2 . VAL A 108 ? 0.10706 0.20134 0.11879 -0.00160 0.00028  0.02574  1114 VAL A CG2 
844  N N   . ARG A 109 ? 0.09715 0.23856 0.09227 0.00933  -0.00675 0.04061  1115 ARG A N   
845  C CA  . ARG A 109 ? 0.10584 0.23999 0.10740 0.02158  -0.01120 0.05497  1115 ARG A CA  
846  C C   . ARG A 109 ? 0.08458 0.24727 0.10543 0.00522  0.00135  0.03310  1115 ARG A C   
847  O O   . ARG A 109 ? 0.11766 0.25644 0.10908 0.00387  0.00588  0.02722  1115 ARG A O   
855  N N   . ARG A 110 ? 0.10525 0.26140 0.11005 0.02604  0.00249  0.03684  1116 ARG A N   
856  C CA  . ARG A 110 ? 0.09486 0.28712 0.12671 -0.00225 0.02091  0.02306  1116 ARG A CA  
857  C C   . ARG A 110 ? 0.09402 0.28430 0.14056 0.00904  -0.00077 0.03372  1116 ARG A C   
858  O O   . ARG A 110 ? 0.12744 0.29039 0.17149 0.02447  -0.03111 0.03502  1116 ARG A O   
859  C CB  . ARG A 110 ? 0.15167 0.29975 0.13382 0.00357  0.03273  0.00477  1116 ARG A CB  
860  C CG  . ARG A 110 ? 0.14845 0.30338 0.13559 -0.01476 0.01691  -0.00699 1116 ARG A CG  
861  C CD  . ARG A 110 ? 0.18275 0.29801 0.13443 -0.00072 0.00996  0.00449  1116 ARG A CD  
862  N NE  . ARG A 110 ? 0.20202 0.29538 0.13425 0.01636  0.00185  0.01250  1116 ARG A NE  
863  C CZ  . ARG A 110 ? 0.16794 0.29267 0.13221 0.02130  0.00165  0.01251  1116 ARG A CZ  
864  N NH1 . ARG A 110 ? 0.17485 0.29482 0.13210 0.02862  -0.01220 0.00843  1116 ARG A NH1 
865  N NH2 . ARG A 110 ? 0.15063 0.29125 0.14554 -0.00132 0.01751  0.00355  1116 ARG A NH2 
866  N N   . ALA A 111 ? 0.09439 0.27769 0.12958 0.00604  -0.00674 0.02926  1117 ALA A N   
867  C CA  . ALA A 111 ? 0.10717 0.30394 0.13702 0.01403  -0.00385 0.02285  1117 ALA A CA  
868  C C   . ALA A 111 ? 0.08732 0.33409 0.14771 0.00698  -0.00337 0.01974  1117 ALA A C   
869  O O   . ALA A 111 ? 0.11107 0.34382 0.13290 0.00576  0.00864  0.04224  1117 ALA A O   
870  C CB  . ALA A 111 ? 0.11247 0.32043 0.13930 0.00419  -0.00559 0.01585  1117 ALA A CB  
871  N N   . VAL A 112 ? 0.09844 0.34606 0.18356 0.01390  -0.00438 -0.01736 1118 VAL A N   
872  C CA  . VAL A 112 ? 0.09912 0.35421 0.21539 0.00777  0.00087  -0.04541 1118 VAL A CA  
873  C C   . VAL A 112 ? 0.11159 0.38673 0.23649 0.00856  0.00009  -0.05173 1118 VAL A C   
874  O O   . VAL A 112 ? 0.12740 0.42721 0.24660 0.02656  -0.02354 -0.03535 1118 VAL A O   
875  C CB  . VAL A 112 ? 0.11980 0.39003 0.23079 0.02851  -0.01290 -0.05968 1118 VAL A CB  
876  C CG1 . VAL A 112 ? 0.15064 0.41763 0.23797 0.04254  -0.00832 -0.06286 1118 VAL A CG1 
877  C CG2 . VAL A 112 ? 0.14049 0.39659 0.23414 0.03182  -0.02166 -0.06960 1118 VAL A CG2 
878  N N   . TYR A 113 ? 0.10836 0.40303 0.24696 -0.01896 0.00920  -0.06240 1119 TYR A N   
879  C CA  . TYR A 113 ? 0.11256 0.41250 0.25664 -0.01360 0.00108  -0.07915 1119 TYR A CA  
880  C C   . TYR A 113 ? 0.11040 0.39795 0.24318 -0.02199 0.00614  -0.08006 1119 TYR A C   
881  O O   . TYR A 113 ? 0.13919 0.34979 0.23384 -0.02885 0.02496  -0.07325 1119 TYR A O   
882  C CB  . TYR A 113 ? 0.12189 0.41916 0.28459 -0.00139 -0.01350 -0.10549 1119 TYR A CB  
883  C CG  . TYR A 113 ? 0.12169 0.41214 0.30648 -0.00240 -0.01651 -0.10521 1119 TYR A CG  
884  C CD1 . TYR A 113 ? 0.13955 0.41833 0.31669 0.00941  -0.03768 -0.11513 1119 TYR A CD1 
885  C CD2 . TYR A 113 ? 0.13037 0.43580 0.32130 0.01931  -0.01580 -0.10408 1119 TYR A CD2 
886  C CE1 . TYR A 113 ? 0.16082 0.42904 0.32553 0.01272  -0.05459 -0.11800 1119 TYR A CE1 
887  C CE2 . TYR A 113 ? 0.14802 0.43691 0.32940 0.02324  -0.03501 -0.10608 1119 TYR A CE2 
888  C CZ  . TYR A 113 ? 0.14800 0.43681 0.33025 0.01292  -0.06070 -0.11012 1119 TYR A CZ  
889  O OH  . TYR A 113 ? 0.16774 0.44686 0.34018 0.02589  -0.08077 -0.11876 1119 TYR A OH  
890  N N   . TYR A 114 ? 0.11473 0.43083 0.23950 -0.00406 -0.01036 -0.06840 1120 TYR A N   
891  C CA  . TYR A 114 ? 0.11825 0.44086 0.24121 -0.02244 -0.01398 -0.05273 1120 TYR A CA  
892  C C   . TYR A 114 ? 0.11512 0.43378 0.22136 0.00027  -0.00762 -0.03443 1120 TYR A C   
893  O O   . TYR A 114 ? 0.12448 0.44130 0.20778 -0.00485 -0.00024 -0.02618 1120 TYR A O   
894  C CB  . TYR A 114 ? 0.13001 0.47648 0.26318 -0.02012 -0.02630 -0.05079 1120 TYR A CB  
895  C CG  . TYR A 114 ? 0.14491 0.51421 0.28118 -0.04143 -0.02890 -0.04182 1120 TYR A CG  
896  C CD1 . TYR A 114 ? 0.17384 0.51923 0.29084 -0.05583 -0.02424 -0.03888 1120 TYR A CD1 
897  C CD2 . TYR A 114 ? 0.14675 0.51959 0.28952 -0.04987 -0.02981 -0.03311 1120 TYR A CD2 
898  C CE1 . TYR A 114 ? 0.17705 0.52931 0.29788 -0.07396 -0.02829 -0.04379 1120 TYR A CE1 
899  C CE2 . TYR A 114 ? 0.15520 0.54383 0.29722 -0.04967 -0.03436 -0.03997 1120 TYR A CE2 
900  C CZ  . TYR A 114 ? 0.17123 0.51655 0.30477 -0.09777 -0.03134 -0.03270 1120 TYR A CZ  
901  O OH  . TYR A 114 ? 0.19087 0.55474 0.31096 -0.07551 -0.03601 -0.03767 1120 TYR A OH  
902  N N   . ASP A 115 ? 0.10975 0.41808 0.21375 0.00107  -0.02180 -0.01944 1121 ASP A N   
903  C CA  . ASP A 115 ? 0.10691 0.39340 0.20710 -0.03617 -0.01725 0.01539  1121 ASP A CA  
904  C C   . ASP A 115 ? 0.13977 0.39052 0.21956 -0.07473 -0.01462 0.03904  1121 ASP A C   
905  O O   . ASP A 115 ? 0.16081 0.40862 0.22717 -0.07744 -0.01183 0.03487  1121 ASP A O   
906  C CB  . ASP A 115 ? 0.12046 0.34209 0.19439 -0.01322 -0.03057 0.01118  1121 ASP A CB  
907  C CG  . ASP A 115 ? 0.13891 0.29535 0.18880 -0.01270 -0.03211 0.02582  1121 ASP A CG  
908  O OD1 . ASP A 115 ? 0.14676 0.28269 0.18396 -0.01385 -0.03579 0.03350  1121 ASP A OD1 
909  O OD2 . ASP A 115 ? 0.14891 0.28211 0.18960 -0.01556 -0.03219 0.04688  1121 ASP A OD2 
910  N N   . PRO A 116 ? 0.18710 0.39638 0.22510 -0.06522 -0.01750 0.05811  1122 PRO A N   
911  C CA  . PRO A 116 ? 0.24259 0.40819 0.23876 -0.06871 -0.00681 0.07734  1122 PRO A CA  
912  C C   . PRO A 116 ? 0.26827 0.38528 0.25833 -0.09316 -0.00096 0.09613  1122 PRO A C   
913  O O   . PRO A 116 ? 0.30967 0.41306 0.26537 -0.07714 0.00398  0.10526  1122 PRO A O   
914  C CB  . PRO A 116 ? 0.27708 0.44996 0.23442 -0.00121 -0.00580 0.07371  1122 PRO A CB  
915  C CG  . PRO A 116 ? 0.26527 0.44199 0.23078 -0.00994 -0.00557 0.06821  1122 PRO A CG  
916  C CD  . PRO A 116 ? 0.20576 0.40306 0.22513 -0.06074 -0.01640 0.05595  1122 PRO A CD  
917  N N   A GLU A 117 ? 0.27484 0.37515 0.25373 -0.08864 -0.01311 0.09307  1123 GLU A N   
918  N N   B GLU A 117 ? 0.25710 0.40060 0.27608 -0.10219 -0.00282 0.07545  1123 GLU A N   
919  C CA  A GLU A 117 ? 0.30083 0.35042 0.24930 -0.05840 -0.02754 0.08725  1123 GLU A CA  
920  C CA  B GLU A 117 ? 0.26901 0.41382 0.29367 -0.07583 -0.00575 0.05210  1123 GLU A CA  
921  C C   A GLU A 117 ? 0.27738 0.27697 0.24050 -0.05329 -0.03036 0.10060  1123 GLU A C   
922  C C   B GLU A 117 ? 0.27661 0.38672 0.30416 -0.07617 -0.00008 0.04611  1123 GLU A C   
923  O O   A GLU A 117 ? 0.31085 0.29888 0.24507 -0.02554 -0.02239 0.10359  1123 GLU A O   
924  O O   B GLU A 117 ? 0.27936 0.37084 0.30749 -0.07726 0.00119  0.05202  1123 GLU A O   
925  C CB  A GLU A 117 ? 0.34233 0.37928 0.25386 -0.04484 -0.03750 0.07013  1123 GLU A CB  
926  C CB  B GLU A 117 ? 0.26473 0.43528 0.29981 -0.06955 -0.01238 0.03803  1123 GLU A CB  
927  C CG  A GLU A 117 ? 0.38851 0.39591 0.25875 -0.02769 -0.04064 0.05767  1123 GLU A CG  
928  C CG  B GLU A 117 ? 0.26912 0.45170 0.30564 -0.05497 -0.01351 0.03068  1123 GLU A CG  
929  C CD  A GLU A 117 ? 0.43471 0.40834 0.26315 -0.00101 -0.04072 0.05019  1123 GLU A CD  
930  C CD  B GLU A 117 ? 0.27687 0.45403 0.31015 -0.05096 -0.01243 0.02810  1123 GLU A CD  
931  O OE1 A GLU A 117 ? 0.45314 0.41218 0.26592 0.00961  -0.04382 0.04231  1123 GLU A OE1 
932  O OE1 B GLU A 117 ? 0.28750 0.45462 0.31063 -0.03116 -0.02226 0.02537  1123 GLU A OE1 
933  O OE2 A GLU A 117 ? 0.44855 0.40153 0.26318 -0.00696 -0.03549 0.05314  1123 GLU A OE2 
934  O OE2 B GLU A 117 ? 0.28983 0.46192 0.31356 -0.04388 -0.00562 0.02597  1123 GLU A OE2 
935  N N   A THR A 118 ? 0.22094 0.24971 0.22821 -0.04512 -0.03995 0.09176  1124 THR A N   
936  N N   B THR A 118 ? 0.28902 0.39576 0.30962 -0.04671 0.00537  0.03254  1124 THR A N   
937  C CA  A THR A 118 ? 0.18777 0.22331 0.21812 -0.01744 -0.04208 0.08420  1124 THR A CA  
938  C CA  B THR A 118 ? 0.27548 0.38731 0.31405 -0.04332 0.01434  0.02814  1124 THR A CA  
939  C C   A THR A 118 ? 0.15941 0.20415 0.21157 -0.01716 -0.03962 0.07091  1124 THR A C   
940  C C   B THR A 118 ? 0.28251 0.39405 0.31736 -0.03779 0.02135  0.03273  1124 THR A C   
941  O O   A THR A 118 ? 0.17155 0.21972 0.21545 -0.00523 -0.03948 0.06424  1124 THR A O   
942  O O   B THR A 118 ? 0.29455 0.41096 0.31995 -0.01478 0.01531  0.02900  1124 THR A O   
943  C CB  A THR A 118 ? 0.18525 0.22801 0.21513 -0.00064 -0.04141 0.08572  1124 THR A CB  
944  C CB  B THR A 118 ? 0.24017 0.36136 0.31400 -0.07829 0.01903  0.02546  1124 THR A CB  
945  O OG1 A THR A 118 ? 0.15963 0.22320 0.21024 -0.00513 -0.03990 0.09032  1124 THR A OG1 
946  O OG1 B THR A 118 ? 0.19744 0.34803 0.31246 -0.11489 0.02858  0.03649  1124 THR A OG1 
947  C CG2 A THR A 118 ? 0.18387 0.23680 0.21503 0.01120  -0.04203 0.08034  1124 THR A CG2 
948  C CG2 B THR A 118 ? 0.23820 0.35139 0.31393 -0.07748 0.01584  0.01651  1124 THR A CG2 
949  N N   A GLY A 119 ? 0.12481 0.19459 0.19987 -0.03557 -0.03001 0.07349  1125 GLY A N   
950  N N   B GLY A 119 ? 0.26913 0.37252 0.31632 -0.06678 0.03611  0.04605  1125 GLY A N   
951  C CA  A GLY A 119 ? 0.10589 0.19999 0.18651 -0.02375 -0.02809 0.06587  1125 GLY A CA  
952  C CA  B GLY A 119 ? 0.27254 0.37591 0.31459 -0.04508 0.04605  0.05494  1125 GLY A CA  
953  C C   A GLY A 119 ? 0.12256 0.20732 0.17394 -0.00750 -0.01994 0.04562  1125 GLY A C   
954  C C   B GLY A 119 ? 0.27966 0.38174 0.31164 -0.01614 0.05615  0.06376  1125 GLY A C   
955  O O   A GLY A 119 ? 0.13101 0.22316 0.17598 -0.02267 -0.03011 0.02033  1125 GLY A O   
956  O O   B GLY A 119 ? 0.28095 0.37383 0.31175 -0.02332 0.05162  0.06283  1125 GLY A O   
957  N N   A LYS A 120 ? 0.11917 0.19972 0.15692 0.01007  -0.00888 0.04244  1126 LYS A N   
958  N N   B LYS A 120 ? 0.29378 0.40069 0.30875 0.01773  0.06985  0.07085  1126 LYS A N   
959  C CA  A LYS A 120 ? 0.11965 0.22383 0.14563 0.02184  0.00041  0.03180  1126 LYS A CA  
960  C CA  B LYS A 120 ? 0.29786 0.42185 0.30375 0.02588  0.08759  0.08574  1126 LYS A CA  
961  C C   A LYS A 120 ? 0.12368 0.18589 0.12846 0.01895  -0.00789 0.01869  1126 LYS A C   
962  C C   B LYS A 120 ? 0.29924 0.39059 0.29000 0.01665  0.08684  0.09165  1126 LYS A C   
963  O O   A LYS A 120 ? 0.13551 0.18760 0.12013 0.02576  -0.01259 0.01309  1126 LYS A O   
964  O O   B LYS A 120 ? 0.28386 0.36669 0.28813 -0.00660 0.08742  0.10165  1126 LYS A O   
965  C CB  A LYS A 120 ? 0.13003 0.28269 0.15563 0.04689  0.00305  0.03633  1126 LYS A CB  
966  C CB  B LYS A 120 ? 0.29790 0.46702 0.31120 0.04493  0.10253  0.09237  1126 LYS A CB  
967  C CG  A LYS A 120 ? 0.17289 0.35895 0.16349 0.09017  0.00641  0.02604  1126 LYS A CG  
968  C CG  B LYS A 120 ? 0.30175 0.51246 0.31763 0.06036  0.11201  0.09635  1126 LYS A CG  
969  C CD  A LYS A 120 ? 0.19905 0.41232 0.16919 0.09871  0.00610  0.01290  1126 LYS A CD  
970  C CD  B LYS A 120 ? 0.31326 0.55102 0.32347 0.08838  0.11575  0.09707  1126 LYS A CD  
971  C CE  A LYS A 120 ? 0.22066 0.45320 0.17295 0.12809  0.00407  -0.00946 1126 LYS A CE  
972  C CE  B LYS A 120 ? 0.31857 0.57577 0.32711 0.10039  0.12009  0.10227  1126 LYS A CE  
973  N NZ  A LYS A 120 ? 0.21552 0.48444 0.17369 0.14722  -0.00335 -0.02609 1126 LYS A NZ  
974  N NZ  B LYS A 120 ? 0.32477 0.59276 0.32987 0.11452  0.12182  0.10531  1126 LYS A NZ  
975  N N   A GLU A 121 ? 0.13166 0.18560 0.12505 0.01224  -0.02020 0.00492  1127 GLU A N   
976  N N   B GLU A 121 ? 0.32699 0.38850 0.27776 0.03534  0.08079  0.08403  1127 GLU A N   
977  C CA  A GLU A 121 ? 0.13851 0.18777 0.12456 -0.01184 -0.02139 0.00412  1127 GLU A CA  
978  C CA  B GLU A 121 ? 0.34630 0.40270 0.26458 0.06425  0.07646  0.07936  1127 GLU A CA  
979  C C   A GLU A 121 ? 0.11537 0.17971 0.11317 -0.02306 -0.01277 0.00613  1127 GLU A C   
980  C C   B GLU A 121 ? 0.29717 0.34187 0.24295 0.03797  0.08026  0.07641  1127 GLU A C   
981  O O   A GLU A 121 ? 0.11650 0.18133 0.11828 0.00005  0.00468  0.02024  1127 GLU A O   
982  O O   B GLU A 121 ? 0.30421 0.35181 0.24199 0.04187  0.09528  0.08287  1127 GLU A O   
983  C CB  A GLU A 121 ? 0.17606 0.19984 0.13644 -0.03214 -0.02814 -0.00127 1127 GLU A CB  
984  C CB  B GLU A 121 ? 0.40901 0.48391 0.27069 0.11116  0.07338  0.07720  1127 GLU A CB  
985  C CG  A GLU A 121 ? 0.22812 0.22849 0.15289 -0.04302 -0.04545 -0.01644 1127 GLU A CG  
986  C CG  B GLU A 121 ? 0.46086 0.55933 0.27563 0.14085  0.07197  0.07478  1127 GLU A CG  
987  C CD  A GLU A 121 ? 0.30453 0.29619 0.16912 0.00716  -0.04903 -0.01848 1127 GLU A CD  
988  C CD  B GLU A 121 ? 0.50166 0.62135 0.28070 0.18772  0.06929  0.06814  1127 GLU A CD  
989  O OE1 A GLU A 121 ? 0.33062 0.35086 0.17760 0.02651  -0.05141 -0.01749 1127 GLU A OE1 
990  O OE1 B GLU A 121 ? 0.51402 0.64512 0.28172 0.19539  0.06866  0.06682  1127 GLU A OE1 
991  O OE2 A GLU A 121 ? 0.32220 0.29530 0.17443 0.00393  -0.04675 -0.01699 1127 GLU A OE2 
992  O OE2 B GLU A 121 ? 0.50915 0.64388 0.28281 0.20639  0.07022  0.06326  1127 GLU A OE2 
993  N N   A ASP A 122 ? 0.12367 0.17520 0.09823 -0.00892 -0.01445 0.01167  1128 ASP A N   
994  N N   B ASP A 122 ? 0.23480 0.28886 0.22154 0.00065  0.06421  0.06377  1128 ASP A N   
995  C CA  A ASP A 122 ? 0.10905 0.18124 0.08440 -0.00832 -0.00496 0.01764  1128 ASP A CA  
996  C CA  B ASP A 122 ? 0.19162 0.28188 0.20064 -0.01380 0.05233  0.05395  1128 ASP A CA  
997  C C   A ASP A 122 ? 0.10704 0.17266 0.07449 -0.00678 -0.00144 0.02290  1128 ASP A C   
998  C C   B ASP A 122 ? 0.16596 0.28082 0.18159 -0.02820 0.04391  0.04233  1128 ASP A C   
999  O O   A ASP A 122 ? 0.11633 0.19802 0.07129 0.01180  0.01476  0.02830  1128 ASP A O   
1000 O O   B ASP A 122 ? 0.16135 0.24573 0.17615 -0.06263 0.03912  0.04047  1128 ASP A O   
1001 C CB  A ASP A 122 ? 0.13099 0.16706 0.08276 -0.01833 -0.00854 0.01600  1128 ASP A CB  
1002 C CB  B ASP A 122 ? 0.15771 0.27824 0.19829 -0.01534 0.04566  0.05244  1128 ASP A CB  
1003 C CG  A ASP A 122 ? 0.11845 0.18749 0.08166 -0.00064 -0.00952 0.01169  1128 ASP A CG  
1004 C CG  B ASP A 122 ? 0.12467 0.25406 0.19482 -0.02044 0.03459  0.04714  1128 ASP A CG  
1005 O OD1 A ASP A 122 ? 0.09932 0.19631 0.08244 0.01021  -0.00057 0.03043  1128 ASP A OD1 
1006 O OD1 B ASP A 122 ? 0.12778 0.25635 0.19491 0.00239  0.01358  0.04544  1128 ASP A OD1 
1007 O OD2 A ASP A 122 ? 0.13803 0.18350 0.08041 0.00862  -0.00467 0.01848  1128 ASP A OD2 
1008 O OD2 B ASP A 122 ? 0.13237 0.24886 0.19331 -0.00355 0.03095  0.03770  1128 ASP A OD2 
1009 N N   A PRO A 123 ? 0.10146 0.17472 0.07665 0.00885  0.00114  0.01491  1129 PRO A N   
1010 N N   B PRO A 123 ? 0.18136 0.28032 0.16840 -0.00121 0.04077  0.03178  1129 PRO A N   
1011 C CA  A PRO A 123 ? 0.10288 0.18010 0.08199 0.00187  -0.00019 0.00693  1129 PRO A CA  
1012 C CA  B PRO A 123 ? 0.15703 0.28499 0.15901 -0.00958 0.02810  0.02216  1129 PRO A CA  
1013 C C   A PRO A 123 ? 0.10369 0.18227 0.08482 0.00436  0.00134  0.01710  1129 PRO A C   
1014 C C   B PRO A 123 ? 0.13278 0.28397 0.14701 -0.00038 0.01954  0.01583  1129 PRO A C   
1015 O O   A PRO A 123 ? 0.10594 0.20065 0.09096 0.01905  0.00990  0.01208  1129 PRO A O   
1016 O O   B PRO A 123 ? 0.10628 0.30648 0.14111 0.00296  0.00712  -0.00129 1129 PRO A O   
1017 C CB  A PRO A 123 ? 0.12673 0.18607 0.08261 0.01785  -0.00190 -0.00148 1129 PRO A CB  
1018 C CB  B PRO A 123 ? 0.18750 0.30587 0.16289 0.01271  0.03027  0.02030  1129 PRO A CB  
1019 C CG  A PRO A 123 ? 0.16130 0.20442 0.08316 0.04241  0.01316  -0.00270 1129 PRO A CG  
1020 C CG  B PRO A 123 ? 0.21625 0.30762 0.16646 0.01034  0.03398  0.02406  1129 PRO A CG  
1021 C CD  A PRO A 123 ? 0.12412 0.17696 0.07708 0.03326  0.01573  0.01473  1129 PRO A CD  
1022 C CD  B PRO A 123 ? 0.20298 0.29631 0.16676 0.00538  0.04393  0.02952  1129 PRO A CD  
1023 N N   A SER A 124 ? 0.11633 0.19709 0.08993 0.00583  -0.00006 0.00906  1130 SER A N   
1024 N N   B SER A 124 ? 0.13939 0.25968 0.14066 0.01966  0.02311  0.03055  1130 SER A N   
1025 C CA  A SER A 124 ? 0.12660 0.21108 0.09108 -0.00480 0.00430  0.01754  1130 SER A CA  
1026 C CA  B SER A 124 ? 0.13134 0.24304 0.13846 0.00777  0.02905  0.03369  1130 SER A CA  
1027 C C   A SER A 124 ? 0.12169 0.19063 0.09150 -0.01753 0.00659  0.00830  1130 SER A C   
1028 C C   B SER A 124 ? 0.12641 0.26117 0.13576 0.03011  0.03090  0.03889  1130 SER A C   
1029 O O   A SER A 124 ? 0.17373 0.18755 0.09581 0.02154  0.02386  0.00196  1130 SER A O   
1030 O O   B SER A 124 ? 0.16989 0.25911 0.13966 0.06234  0.03676  0.03871  1130 SER A O   
1031 C CB  A SER A 124 ? 0.12737 0.22820 0.09413 -0.02628 0.00845  0.03613  1130 SER A CB  
1032 C CB  B SER A 124 ? 0.11918 0.25556 0.14161 0.00715  0.02234  0.03228  1130 SER A CB  
1033 O OG  A SER A 124 ? 0.17716 0.26960 0.10931 0.00353  0.00758  0.03713  1130 SER A OG  
1034 O OG  B SER A 124 ? 0.12655 0.25512 0.14242 0.01516  0.01788  0.04012  1130 SER A OG  
1035 N N   A LYS A 125 ? 0.08707 0.21174 0.08611 -0.00393 -0.00235 0.02391  1131 LYS A N   
1036 N N   B LYS A 125 ? 0.10033 0.28383 0.13061 0.00843  0.01947  0.03177  1131 LYS A N   
1037 C CA  A LYS A 125 ? 0.10061 0.24164 0.08946 -0.00960 0.00267  0.02997  1131 LYS A CA  
1038 C CA  B LYS A 125 ? 0.08726 0.30953 0.12940 0.00003  0.00513  0.03559  1131 LYS A CA  
1039 C C   A LYS A 125 ? 0.09802 0.24016 0.08896 -0.01264 0.00153  0.02556  1131 LYS A C   
1040 C C   B LYS A 125 ? 0.10239 0.31996 0.12813 0.00867  0.00984  0.04217  1131 LYS A C   
1041 O O   A LYS A 125 ? 0.11759 0.24991 0.08983 -0.01195 0.01252  0.02917  1131 LYS A O   
1042 O O   B LYS A 125 ? 0.09745 0.34446 0.12888 0.01479  0.01568  0.04760  1131 LYS A O   
1043 C CB  A LYS A 125 ? 0.11600 0.26665 0.09741 0.00276  -0.00582 0.02451  1131 LYS A CB  
1044 C CB  B LYS A 125 ? 0.08750 0.32333 0.13297 -0.02120 -0.01033 0.03047  1131 LYS A CB  
1045 C CG  A LYS A 125 ? 0.12598 0.25911 0.10406 0.00564  -0.00375 0.02227  1131 LYS A CG  
1046 C CG  B LYS A 125 ? 0.09525 0.34818 0.13964 -0.02069 -0.01779 0.01807  1131 LYS A CG  
1047 C CD  A LYS A 125 ? 0.13645 0.25664 0.11352 0.00758  0.00218  0.02863  1131 LYS A CD  
1048 C CD  B LYS A 125 ? 0.10177 0.36138 0.14795 -0.02886 -0.02113 0.01935  1131 LYS A CD  
1049 C CE  A LYS A 125 ? 0.14989 0.25536 0.12146 0.01795  -0.00009 0.03339  1131 LYS A CE  
1050 C CE  B LYS A 125 ? 0.10468 0.36620 0.15575 -0.02929 -0.02454 0.01930  1131 LYS A CE  
1051 N NZ  A LYS A 125 ? 0.16745 0.26592 0.12509 0.04611  -0.00669 0.03233  1131 LYS A NZ  
1052 N NZ  B LYS A 125 ? 0.10647 0.35227 0.16065 -0.04537 -0.02512 0.00942  1131 LYS A NZ  
1053 N N   A ASN A 126 ? 0.09596 0.24038 0.08795 -0.00667 -0.01377 0.02441  1132 ASN A N   
1054 N N   B ASN A 126 ? 0.10895 0.31777 0.12794 0.00148  0.00468  0.03253  1132 ASN A N   
1055 C CA  A ASN A 126 ? 0.11466 0.25251 0.09247 0.00073  -0.00431 0.02637  1132 ASN A CA  
1056 C CA  B ASN A 126 ? 0.08598 0.32712 0.12646 -0.02397 -0.00313 0.02693  1132 ASN A CA  
1057 C C   A ASN A 126 ? 0.13057 0.24357 0.09867 0.01087  -0.00212 0.03187  1132 ASN A C   
1058 C C   B ASN A 126 ? 0.08348 0.32243 0.12236 -0.00403 0.00478  0.03623  1132 ASN A C   
1059 O O   A ASN A 126 ? 0.14248 0.24392 0.11291 0.01910  -0.00060 0.03463  1132 ASN A O   
1060 O O   B ASN A 126 ? 0.08940 0.33014 0.13299 -0.01786 0.00912  0.03695  1132 ASN A O   
1061 C CB  A ASN A 126 ? 0.11806 0.24933 0.09493 0.00575  -0.00597 0.02237  1132 ASN A CB  
1062 C CB  B ASN A 126 ? 0.11336 0.35479 0.12764 -0.00719 -0.00239 0.03341  1132 ASN A CB  
1063 C CG  A ASN A 126 ? 0.12548 0.23261 0.09865 0.01528  -0.00881 0.03427  1132 ASN A CG  
1064 C CG  B ASN A 126 ? 0.16098 0.39092 0.13575 0.01516  -0.00355 0.03510  1132 ASN A CG  
1065 O OD1 A ASN A 126 ? 0.12741 0.24473 0.09775 0.03959  -0.01029 0.03764  1132 ASN A OD1 
1066 O OD1 B ASN A 126 ? 0.20705 0.39148 0.13939 0.01871  -0.00352 0.04057  1132 ASN A OD1 
1067 N ND2 A ASN A 126 ? 0.15305 0.24573 0.10492 0.04168  -0.00918 0.03475  1132 ASN A ND2 
1068 N ND2 B ASN A 126 ? 0.16345 0.40569 0.14052 0.02060  -0.00161 0.03136  1132 ASN A ND2 
1069 N N   A GLY A 127 ? 0.12026 0.22966 0.09092 0.00507  -0.00495 0.02782  1133 GLY A N   
1070 N N   B GLY A 127 ? 0.09133 0.31241 0.11644 -0.01004 0.01578  0.03958  1133 GLY A N   
1071 C CA  A GLY A 127 ? 0.10375 0.23757 0.08365 0.00606  0.00095  0.02532  1133 GLY A CA  
1072 C CA  B GLY A 127 ? 0.10971 0.32524 0.10973 0.01248  0.01939  0.05068  1133 GLY A CA  
1073 C C   A GLY A 127 ? 0.10315 0.23625 0.08162 -0.02194 -0.00467 0.01908  1133 GLY A C   
1074 C C   B GLY A 127 ? 0.11734 0.30941 0.10883 -0.01657 0.00694  0.04805  1133 GLY A C   
1075 O O   A GLY A 127 ? 0.12447 0.24686 0.07920 0.01049  -0.01495 0.01406  1133 GLY A O   
1076 O O   B GLY A 127 ? 0.15597 0.33551 0.10688 0.02275  0.00334  0.04321  1133 GLY A O   
1077 N N   A VAL A 128 ? 0.11047 0.23228 0.08023 -0.04279 -0.00030 0.03269  1134 VAL A N   
1078 N N   B VAL A 128 ? 0.11867 0.28058 0.10696 -0.04738 -0.00866 0.04863  1134 VAL A N   
1079 C CA  A VAL A 128 ? 0.13004 0.24405 0.08569 -0.02056 -0.00569 0.03258  1134 VAL A CA  
1080 C CA  B VAL A 128 ? 0.11547 0.27571 0.10827 -0.05368 -0.02308 0.04104  1134 VAL A CA  
1081 C C   A VAL A 128 ? 0.11262 0.25383 0.08195 -0.02737 -0.00457 0.04222  1134 VAL A C   
1082 C C   B VAL A 128 ? 0.09742 0.27313 0.09714 -0.06417 -0.01322 0.04374  1134 VAL A C   
1083 O O   A VAL A 128 ? 0.12158 0.22083 0.07318 -0.03325 -0.00231 0.04317  1134 VAL A O   
1084 O O   B VAL A 128 ? 0.10525 0.27771 0.09789 -0.06861 -0.01012 0.04555  1134 VAL A O   
1085 C CB  A VAL A 128 ? 0.13580 0.22363 0.09747 -0.03056 -0.00298 0.03116  1134 VAL A CB  
1086 C CB  B VAL A 128 ? 0.13398 0.26509 0.12233 -0.05532 -0.02141 0.03867  1134 VAL A CB  
1087 C CG1 A VAL A 128 ? 0.15791 0.24403 0.10197 -0.00996 0.00124  0.03409  1134 VAL A CG1 
1088 C CG1 B VAL A 128 ? 0.13832 0.25680 0.12975 -0.06907 -0.02593 0.03350  1134 VAL A CG1 
1089 C CG2 A VAL A 128 ? 0.14924 0.21806 0.10337 -0.03103 -0.00372 0.01902  1134 VAL A CG2 
1090 C CG2 B VAL A 128 ? 0.14685 0.26493 0.12886 -0.03876 -0.02134 0.03840  1134 VAL A CG2 
1091 N N   . CYS A 129 ? 0.10330 0.27475 0.09058 -0.04704 -0.00384 0.04026  1135 CYS A N   
1092 C CA  . CYS A 129 ? 0.10402 0.26594 0.08729 -0.02587 -0.00137 0.02096  1135 CYS A CA  
1093 C C   . CYS A 129 ? 0.10271 0.23254 0.07716 -0.02249 -0.00486 0.03197  1135 CYS A C   
1094 O O   . CYS A 129 ? 0.10377 0.22905 0.08017 -0.01590 -0.01000 0.02282  1135 CYS A O   
1095 C CB  . CYS A 129 ? 0.12822 0.27142 0.08860 -0.01741 -0.01086 0.00672  1135 CYS A CB  
1096 S SG  . CYS A 129 ? 0.11985 0.24289 0.08259 -0.02773 -0.00271 0.01771  1135 CYS A SG  
1097 N N   . SER A 130 ? 0.09930 0.24205 0.08275 -0.01645 -0.00701 0.02781  1136 SER A N   
1098 C CA  . SER A 130 ? 0.10343 0.24342 0.07687 0.00956  -0.00220 0.02547  1136 SER A CA  
1099 C C   . SER A 130 ? 0.09998 0.24032 0.08318 0.01324  -0.01125 0.02326  1136 SER A C   
1100 O O   . SER A 130 ? 0.11756 0.23258 0.08779 -0.00591 -0.01288 0.02557  1136 SER A O   
1101 C CB  . SER A 130 ? 0.09524 0.25949 0.07465 0.01674  0.00049  0.01728  1136 SER A CB  
1102 O OG  . SER A 130 ? 0.10074 0.26384 0.07899 -0.00100 -0.00180 0.02291  1136 SER A OG  
1103 N N   . ASN A 131 ? 0.10608 0.26842 0.08069 0.00558  0.00437  0.03024  1137 ASN A N   
1104 C CA  . ASN A 131 ? 0.10874 0.29140 0.08299 0.02353  -0.00197 0.02972  1137 ASN A CA  
1105 C C   . ASN A 131 ? 0.10784 0.26759 0.07982 0.00548  -0.00154 0.03012  1137 ASN A C   
1106 O O   . ASN A 131 ? 0.11050 0.26339 0.08172 -0.00861 -0.00147 0.02253  1137 ASN A O   
1107 C CB  . ASN A 131 ? 0.11383 0.32576 0.09628 0.02262  -0.00597 0.01789  1137 ASN A CB  
1108 C CG  . ASN A 131 ? 0.13848 0.36038 0.11090 0.04046  -0.01497 -0.00288 1137 ASN A CG  
1109 O OD1 . ASN A 131 ? 0.15952 0.31821 0.12372 0.02999  -0.01314 -0.00340 1137 ASN A OD1 
1110 N ND2 . ASN A 131 ? 0.11602 0.36935 0.10534 0.02266  -0.01544 0.00534  1137 ASN A ND2 
1111 N N   . PHE A 132 ? 0.10465 0.27703 0.08652 -0.01065 -0.00255 0.02297  1138 PHE A N   
1112 C CA  . PHE A 132 ? 0.11463 0.25338 0.08348 -0.01904 -0.00398 0.03055  1138 PHE A CA  
1113 C C   . PHE A 132 ? 0.10980 0.22143 0.07414 -0.01860 -0.00463 0.03154  1138 PHE A C   
1114 O O   . PHE A 132 ? 0.11810 0.23593 0.06611 -0.01730 -0.00339 0.02730  1138 PHE A O   
1115 C CB  . PHE A 132 ? 0.12126 0.23493 0.08679 -0.02293 -0.00855 0.02494  1138 PHE A CB  
1116 C CG  . PHE A 132 ? 0.11304 0.23921 0.08182 -0.03764 -0.00447 0.02432  1138 PHE A CG  
1117 C CD1 . PHE A 132 ? 0.13303 0.22275 0.08023 -0.03090 -0.00995 0.02477  1138 PHE A CD1 
1118 C CD2 . PHE A 132 ? 0.13175 0.25522 0.08430 -0.02521 -0.00206 0.01880  1138 PHE A CD2 
1119 C CE1 . PHE A 132 ? 0.15739 0.24041 0.08486 -0.03129 -0.01243 0.01077  1138 PHE A CE1 
1120 C CE2 . PHE A 132 ? 0.14323 0.26127 0.09122 -0.00869 -0.01324 0.00197  1138 PHE A CE2 
1121 C CZ  . PHE A 132 ? 0.15030 0.24483 0.09083 -0.02053 -0.01830 0.00398  1138 PHE A CZ  
1122 N N   . LEU A 133 ? 0.10464 0.21585 0.07673 -0.02002 -0.00246 0.02437  1139 LEU A N   
1123 C CA  . LEU A 133 ? 0.10825 0.19890 0.08150 -0.00844 0.00357  0.02979  1139 LEU A CA  
1124 C C   . LEU A 133 ? 0.09501 0.21087 0.07626 -0.00057 0.00314  0.03091  1139 LEU A C   
1125 O O   . LEU A 133 ? 0.10615 0.21551 0.07987 -0.00319 -0.00099 0.02114  1139 LEU A O   
1126 C CB  . LEU A 133 ? 0.11186 0.20173 0.08525 -0.01198 0.00356  0.02892  1139 LEU A CB  
1127 C CG  . LEU A 133 ? 0.11560 0.20632 0.09233 -0.02315 -0.00245 0.00828  1139 LEU A CG  
1128 C CD1 . LEU A 133 ? 0.13022 0.21477 0.09512 -0.01636 0.01211  0.00161  1139 LEU A CD1 
1129 C CD2 . LEU A 133 ? 0.13977 0.22832 0.10470 -0.00213 -0.01211 -0.00265 1139 LEU A CD2 
1130 N N   . CYS A 134 ? 0.11592 0.20345 0.07814 0.00484  -0.00074 0.02585  1140 CYS A N   
1131 C CA  . CYS A 134 ? 0.13647 0.21915 0.08230 0.01526  0.00666  0.03588  1140 CYS A CA  
1132 C C   . CYS A 134 ? 0.13016 0.21122 0.08387 0.01369  0.00752  0.02079  1140 CYS A C   
1133 O O   . CYS A 134 ? 0.13762 0.21531 0.08835 0.00651  0.01149  0.02975  1140 CYS A O   
1134 C CB  . CYS A 134 ? 0.19375 0.22766 0.08887 0.02525  0.01737  0.03931  1140 CYS A CB  
1135 S SG  . CYS A 134 ? 0.25495 0.23159 0.09664 0.03992  0.01964  0.04439  1140 CYS A SG  
1136 N N   . ASN A 135 ? 0.11818 0.22003 0.07934 0.00239  0.00972  0.02722  1141 ASN A N   
1137 C CA  . ASN A 135 ? 0.10363 0.22950 0.08407 -0.00123 0.00163  0.03015  1141 ASN A CA  
1138 C C   . ASN A 135 ? 0.11411 0.21620 0.08289 0.00013  0.00892  0.02743  1141 ASN A C   
1139 O O   . ASN A 135 ? 0.12666 0.20951 0.07608 0.00707  0.00361  0.02321  1141 ASN A O   
1140 C CB  . ASN A 135 ? 0.11264 0.24225 0.09249 0.00256  0.00580  0.03541  1141 ASN A CB  
1141 C CG  . ASN A 135 ? 0.12394 0.24167 0.10224 0.00788  0.01953  0.02763  1141 ASN A CG  
1142 O OD1 . ASN A 135 ? 0.11973 0.26101 0.11462 0.02372  0.00374  0.02073  1141 ASN A OD1 
1143 N ND2 . ASN A 135 ? 0.11244 0.26838 0.10905 -0.00127 0.00748  0.01834  1141 ASN A ND2 
1144 N N   . SER A 136 ? 0.11519 0.19734 0.08912 0.00447  -0.00217 0.02618  1142 SER A N   
1145 C CA  . SER A 136 ? 0.11855 0.19476 0.08688 -0.00159 -0.00204 0.01263  1142 SER A CA  
1146 C C   . SER A 136 ? 0.12832 0.17705 0.08595 0.00486  0.00576  0.02458  1142 SER A C   
1147 O O   . SER A 136 ? 0.14897 0.19417 0.08957 0.00350  -0.00292 0.03016  1142 SER A O   
1148 C CB  . SER A 136 ? 0.11894 0.20261 0.08619 -0.00561 0.00431  0.01426  1142 SER A CB  
1149 O OG  . SER A 136 ? 0.11272 0.19183 0.08015 -0.01808 -0.00542 0.02168  1142 SER A OG  
1150 N N   . LYS A 137 ? 0.11956 0.18949 0.08709 -0.00215 -0.00582 0.01438  1143 LYS A N   
1151 C CA  . LYS A 137 ? 0.11691 0.17944 0.09339 -0.01060 0.00055  0.00985  1143 LYS A CA  
1152 C C   . LYS A 137 ? 0.10934 0.17535 0.08312 -0.02699 0.00500  0.00554  1143 LYS A C   
1153 O O   . LYS A 137 ? 0.11707 0.18515 0.06860 -0.01175 0.00229  0.00962  1143 LYS A O   
1154 C CB  . LYS A 137 ? 0.13749 0.19664 0.11008 -0.00093 0.01467  0.01505  1143 LYS A CB  
1155 C CG  . LYS A 137 ? 0.15703 0.20445 0.13713 0.01662  0.01386  0.01339  1143 LYS A CG  
1156 C CD  . LYS A 137 ? 0.20182 0.21502 0.16766 0.02582  0.01188  0.02133  1143 LYS A CD  
1157 C CE  . LYS A 137 ? 0.28092 0.27897 0.18955 0.08188  0.01994  0.03298  1143 LYS A CE  
1158 N NZ  . LYS A 137 ? 0.35961 0.32092 0.20358 0.09993  0.01931  0.03970  1143 LYS A NZ  
1159 N N   . PRO A 138 ? 0.13560 0.18214 0.09066 0.00045  -0.00137 0.01113  1144 PRO A N   
1160 C CA  . PRO A 138 ? 0.11538 0.18939 0.08707 -0.01708 -0.00426 0.00504  1144 PRO A CA  
1161 C C   . PRO A 138 ? 0.11368 0.19426 0.07889 -0.01764 -0.00238 0.00639  1144 PRO A C   
1162 O O   . PRO A 138 ? 0.13152 0.19691 0.08064 -0.01025 0.00877  0.00508  1144 PRO A O   
1163 C CB  . PRO A 138 ? 0.14188 0.20257 0.09793 -0.02512 -0.01095 -0.00197 1144 PRO A CB  
1164 C CG  . PRO A 138 ? 0.14883 0.19858 0.10412 -0.02715 -0.00864 0.00538  1144 PRO A CG  
1165 C CD  . PRO A 138 ? 0.15270 0.18542 0.10307 -0.01997 -0.00602 0.00292  1144 PRO A CD  
1166 N N   . GLY A 139 ? 0.10963 0.19690 0.07601 -0.01197 -0.00614 0.00151  1145 GLY A N   
1167 C CA  . GLY A 139 ? 0.11937 0.17795 0.07961 -0.01199 -0.00791 0.00633  1145 GLY A CA  
1168 C C   . GLY A 139 ? 0.11935 0.19092 0.07452 0.00269  -0.00034 0.00724  1145 GLY A C   
1169 O O   . GLY A 139 ? 0.14568 0.19600 0.08124 -0.00602 -0.02178 0.02041  1145 GLY A O   
1170 N N   . ASP A 140 ? 0.10983 0.18808 0.06164 -0.00071 -0.00368 0.00535  1146 ASP A N   
1171 C CA  . ASP A 140 ? 0.10611 0.18989 0.06730 -0.00538 0.00063  -0.00046 1146 ASP A CA  
1172 C C   . ASP A 140 ? 0.10061 0.19016 0.07202 -0.01475 0.00562  0.00062  1146 ASP A C   
1173 O O   . ASP A 140 ? 0.11196 0.21309 0.08711 -0.01403 0.01071  0.01020  1146 ASP A O   
1174 C CB  . ASP A 140 ? 0.10393 0.18310 0.07493 -0.00519 0.00803  0.00845  1146 ASP A CB  
1175 C CG  . ASP A 140 ? 0.10372 0.16535 0.07557 -0.01759 0.00433  0.01807  1146 ASP A CG  
1176 O OD1 . ASP A 140 ? 0.11582 0.19821 0.07824 -0.00231 0.01073  0.02207  1146 ASP A OD1 
1177 O OD2 . ASP A 140 ? 0.11426 0.17721 0.07777 -0.00702 0.00185  0.02237  1146 ASP A OD2 
1178 N N   . LYS A 141 ? 0.11221 0.18594 0.07059 -0.00518 0.00485  -0.00110 1147 LYS A N   
1179 C CA  . LYS A 141 ? 0.10099 0.19922 0.08646 -0.00514 0.00156  -0.00662 1147 LYS A CA  
1180 C C   . LYS A 141 ? 0.10906 0.22712 0.09240 -0.00062 -0.00294 -0.01689 1147 LYS A C   
1181 O O   . LYS A 141 ? 0.11869 0.28446 0.10164 0.01652  -0.01678 -0.04040 1147 LYS A O   
1182 C CB  . LYS A 141 ? 0.12399 0.20422 0.10104 -0.00515 0.00041  0.00355  1147 LYS A CB  
1183 C CG  . LYS A 141 ? 0.13430 0.23446 0.11074 -0.00412 -0.00450 0.02562  1147 LYS A CG  
1184 C CD  . LYS A 141 ? 0.13398 0.27461 0.11667 -0.00851 -0.01862 0.03595  1147 LYS A CD  
1185 C CE  . LYS A 141 ? 0.16977 0.32249 0.12595 -0.04222 -0.03412 0.04947  1147 LYS A CE  
1186 N NZ  . LYS A 141 ? 0.21695 0.35286 0.13242 0.01903  -0.01108 0.04665  1147 LYS A NZ  
1187 N N   . ILE A 142 ? 0.13502 0.19925 0.08117 -0.00654 -0.00865 -0.02083 1148 ILE A N   
1188 C CA  . ILE A 142 ? 0.20410 0.24179 0.08640 0.03880  -0.02062 -0.02321 1148 ILE A CA  
1189 C C   . ILE A 142 ? 0.15829 0.24382 0.09271 0.01624  -0.01549 -0.03442 1148 ILE A C   
1190 O O   . ILE A 142 ? 0.17807 0.26808 0.11660 0.03278  -0.04653 -0.05285 1148 ILE A O   
1191 C CB  . ILE A 142 ? 0.25189 0.27482 0.11240 0.02545  -0.03775 -0.02089 1148 ILE A CB  
1192 C CG1 . ILE A 142 ? 0.19024 0.34079 0.13329 -0.03238 -0.01349 -0.00029 1148 ILE A CG1 
1193 C CG2 . ILE A 142 ? 0.27356 0.30217 0.10983 0.00544  -0.04201 -0.01404 1148 ILE A CG2 
1194 C CD1 . ILE A 142 ? 0.13344 0.39196 0.14379 -0.04785 -0.00718 0.00197  1148 ILE A CD1 
1195 N N   . GLN A 143 ? 0.15462 0.21570 0.08173 -0.00765 0.00376  -0.00768 1149 GLN A N   
1196 C CA  . GLN A 143 ? 0.16792 0.20521 0.07837 -0.01442 0.00730  0.00322  1149 GLN A CA  
1197 C C   . GLN A 143 ? 0.13045 0.20026 0.07668 -0.02162 -0.00300 0.00168  1149 GLN A C   
1198 O O   . GLN A 143 ? 0.11804 0.24335 0.08152 -0.00610 0.00590  0.00683  1149 GLN A O   
1199 C CB  . GLN A 143 ? 0.18876 0.24168 0.09456 -0.03309 0.01558  0.01457  1149 GLN A CB  
1200 C CG  . GLN A 143 ? 0.21056 0.28507 0.11472 -0.03557 0.00911  0.02336  1149 GLN A CG  
1201 C CD  . GLN A 143 ? 0.24404 0.30384 0.13925 -0.03540 0.00541  0.01909  1149 GLN A CD  
1202 O OE1 . GLN A 143 ? 0.25352 0.30734 0.15330 -0.03919 -0.01517 0.02597  1149 GLN A OE1 
1203 N NE2 . GLN A 143 ? 0.28969 0.37478 0.15046 0.00654  0.01572  0.00396  1149 GLN A NE2 
1204 N N   . LEU A 144 ? 0.13809 0.20387 0.08615 -0.02214 -0.00845 0.01251  1150 LEU A N   
1205 C CA  . LEU A 144 ? 0.11308 0.19778 0.10983 -0.03496 0.00105  0.02060  1150 LEU A CA  
1206 C C   . LEU A 144 ? 0.12667 0.21060 0.09220 -0.01979 0.00906  0.02377  1150 LEU A C   
1207 O O   . LEU A 144 ? 0.15966 0.21539 0.09134 0.00612  0.01914  0.03057  1150 LEU A O   
1208 C CB  . LEU A 144 ? 0.15592 0.25712 0.14118 -0.01309 -0.02031 0.03312  1150 LEU A CB  
1209 C CG  . LEU A 144 ? 0.17255 0.24800 0.15687 -0.03396 -0.02824 0.02820  1150 LEU A CG  
1210 C CD1 . LEU A 144 ? 0.21140 0.21487 0.16030 -0.02423 -0.05834 0.02317  1150 LEU A CD1 
1211 C CD2 . LEU A 144 ? 0.16435 0.21355 0.15645 -0.04219 -0.04129 0.03221  1150 LEU A CD2 
1212 N N   . THR A 145 ? 0.13640 0.22012 0.08732 -0.01446 0.01839  0.02080  1151 THR A N   
1213 C CA  . THR A 145 ? 0.13945 0.21688 0.09564 -0.01564 0.01722  0.02760  1151 THR A CA  
1214 C C   . THR A 145 ? 0.13435 0.20663 0.09631 -0.01119 0.00721  0.01931  1151 THR A C   
1215 O O   . THR A 145 ? 0.12766 0.19864 0.09961 -0.01365 0.00947  0.01839  1151 THR A O   
1216 C CB  . THR A 145 ? 0.14925 0.25195 0.11288 -0.02468 0.00736  0.03739  1151 THR A CB  
1217 O OG1 . THR A 145 ? 0.14576 0.25290 0.11737 -0.03398 -0.00521 0.01985  1151 THR A OG1 
1218 C CG2 . THR A 145 ? 0.16257 0.27107 0.12417 -0.04433 0.00588  0.04025  1151 THR A CG2 
1219 N N   . GLY A 146 ? 0.14348 0.20157 0.09509 0.00115  0.01595  0.02029  1152 GLY A N   
1220 C CA  . GLY A 146 ? 0.13948 0.21382 0.09456 -0.00814 0.01226  0.02051  1152 GLY A CA  
1221 C C   . GLY A 146 ? 0.14344 0.16786 0.09142 -0.01048 0.01128  0.01182  1152 GLY A C   
1222 O O   . GLY A 146 ? 0.15963 0.17055 0.08865 -0.00169 0.00524  0.01431  1152 GLY A O   
1223 N N   . PRO A 147 ? 0.13945 0.18222 0.08624 -0.00376 0.00219  0.00532  1153 PRO A N   
1224 C CA  . PRO A 147 ? 0.14513 0.16614 0.09058 -0.01409 -0.00642 0.00806  1153 PRO A CA  
1225 C C   . PRO A 147 ? 0.15098 0.15539 0.08444 -0.01413 0.00750  0.00788  1153 PRO A C   
1226 O O   . PRO A 147 ? 0.16696 0.18605 0.09818 -0.01175 0.01579  0.00113  1153 PRO A O   
1227 C CB  . PRO A 147 ? 0.14902 0.19708 0.10380 -0.02047 -0.01446 0.01865  1153 PRO A CB  
1228 C CG  . PRO A 147 ? 0.15730 0.19232 0.10837 -0.02002 0.00096  0.01701  1153 PRO A CG  
1229 C CD  . PRO A 147 ? 0.14228 0.18661 0.09462 -0.02724 -0.00178 0.00861  1153 PRO A CD  
1230 N N   . SER A 148 ? 0.16909 0.17189 0.07390 -0.03230 -0.00969 0.00212  1154 SER A N   
1231 C CA  . SER A 148 ? 0.21396 0.20255 0.08358 -0.02630 -0.00360 -0.00554 1154 SER A CA  
1232 C C   . SER A 148 ? 0.19943 0.20400 0.08075 -0.00757 0.00528  -0.00293 1154 SER A C   
1233 O O   . SER A 148 ? 0.21261 0.20997 0.08051 -0.00271 0.01524  0.01040  1154 SER A O   
1234 C CB  . SER A 148 ? 0.21670 0.24202 0.10262 -0.02397 -0.00100 -0.00332 1154 SER A CB  
1235 O OG  . SER A 148 ? 0.18359 0.26797 0.10871 -0.01891 -0.00251 0.01556  1154 SER A OG  
1236 N N   . GLY A 149 ? 0.20389 0.22407 0.07719 0.00943  -0.00423 -0.00329 1155 GLY A N   
1237 C CA  . GLY A 149 ? 0.20234 0.24845 0.07877 0.00242  0.00837  0.01968  1155 GLY A CA  
1238 C C   . GLY A 149 ? 0.19549 0.19371 0.08529 -0.03572 -0.01505 -0.00294 1155 GLY A C   
1239 O O   . GLY A 149 ? 0.23606 0.19617 0.10146 -0.01149 -0.03820 -0.01083 1155 GLY A O   
1240 N N   . LYS A 150 ? 0.17405 0.18941 0.09132 -0.03681 0.00051  0.00580  1156 LYS A N   
1241 C CA  . LYS A 150 ? 0.18184 0.18379 0.11363 -0.01931 -0.00150 0.01205  1156 LYS A CA  
1242 C C   . LYS A 150 ? 0.16104 0.18871 0.10661 -0.04413 -0.01335 0.00982  1156 LYS A C   
1243 O O   . LYS A 150 ? 0.17334 0.19769 0.11173 -0.02721 -0.01132 0.02653  1156 LYS A O   
1244 C CB  . LYS A 150 ? 0.24197 0.23367 0.14370 0.01329  0.03442  0.03435  1156 LYS A CB  
1245 C CG  . LYS A 150 ? 0.29811 0.29941 0.16646 0.04550  0.04029  0.04235  1156 LYS A CG  
1246 C CD  . LYS A 150 ? 0.37440 0.40673 0.18344 0.10181  0.03338  0.03007  1156 LYS A CD  
1247 C CE  . LYS A 150 ? 0.42765 0.48735 0.19409 0.14425  0.03800  0.01924  1156 LYS A CE  
1248 N NZ  . LYS A 150 ? 0.46163 0.54054 0.20249 0.17959  0.03496  0.01543  1156 LYS A NZ  
1249 N N   . ILE A 151 ? 0.16431 0.19959 0.10610 -0.05035 -0.03222 0.01051  1157 ILE A N   
1250 C CA  . ILE A 151 ? 0.17211 0.20589 0.11404 -0.03778 -0.04333 0.00897  1157 ILE A CA  
1251 C C   . ILE A 151 ? 0.15541 0.18705 0.09321 -0.03313 -0.02424 0.01210  1157 ILE A C   
1252 O O   . ILE A 151 ? 0.19757 0.18847 0.09061 -0.02800 -0.01041 0.01646  1157 ILE A O   
1253 C CB  . ILE A 151 ? 0.19665 0.24015 0.14573 -0.05055 -0.06094 0.01487  1157 ILE A CB  
1254 C CG1 . ILE A 151 ? 0.23186 0.28189 0.17254 -0.04673 -0.05729 0.02042  1157 ILE A CG1 
1255 C CG2 . ILE A 151 ? 0.21907 0.26084 0.15009 -0.01533 -0.05215 0.01677  1157 ILE A CG2 
1256 C CD1 . ILE A 151 ? 0.23606 0.33204 0.18219 -0.04916 -0.06167 0.02643  1157 ILE A CD1 
1257 N N   . MET A 152 ? 0.14425 0.18550 0.07932 -0.03762 -0.02360 0.00700  1158 MET A N   
1258 C CA  . MET A 152 ? 0.13811 0.18656 0.07884 -0.03057 -0.01803 0.01231  1158 MET A CA  
1259 C C   . MET A 152 ? 0.14137 0.16950 0.06904 -0.02731 -0.00658 0.01788  1158 MET A C   
1260 O O   . MET A 152 ? 0.14938 0.16385 0.07690 -0.01466 -0.01132 0.02140  1158 MET A O   
1261 C CB  . MET A 152 ? 0.13275 0.26074 0.08848 0.00287  -0.01732 0.00614  1158 MET A CB  
1262 C CG  . MET A 152 ? 0.13137 0.23554 0.09926 -0.00668 -0.00058 0.03744  1158 MET A CG  
1263 S SD  . MET A 152 ? 0.13505 0.21941 0.10168 -0.01514 -0.00644 0.03899  1158 MET A SD  
1264 C CE  . MET A 152 ? 0.20387 0.21485 0.11722 -0.00067 0.01996  0.02580  1158 MET A CE  
1265 N N   . LEU A 153 ? 0.13708 0.17263 0.07126 -0.02041 -0.01237 0.01044  1159 LEU A N   
1266 C CA  . LEU A 153 ? 0.14208 0.17768 0.08297 -0.03376 -0.00262 0.01525  1159 LEU A CA  
1267 C C   . LEU A 153 ? 0.14005 0.20523 0.07658 -0.03640 -0.00165 0.01212  1159 LEU A C   
1268 O O   . LEU A 153 ? 0.18747 0.23502 0.07696 -0.05787 -0.00848 0.01908  1159 LEU A O   
1269 C CB  . LEU A 153 ? 0.14174 0.19872 0.09198 -0.00921 -0.00102 0.01095  1159 LEU A CB  
1270 C CG  . LEU A 153 ? 0.15606 0.18784 0.10273 -0.01158 -0.01255 -0.00530 1159 LEU A CG  
1271 C CD1 . LEU A 153 ? 0.22954 0.22294 0.11277 0.04018  -0.01860 -0.01239 1159 LEU A CD1 
1272 C CD2 . LEU A 153 ? 0.17479 0.19713 0.10694 -0.00308 0.00996  0.01041  1159 LEU A CD2 
1273 N N   . LEU A 154 ? 0.12190 0.18476 0.08531 -0.02688 0.00569  0.01161  1160 LEU A N   
1274 C CA  . LEU A 154 ? 0.11706 0.17547 0.09065 -0.01031 0.00567  0.01776  1160 LEU A CA  
1275 C C   . LEU A 154 ? 0.11828 0.16999 0.08308 -0.01750 -0.00118 0.02603  1160 LEU A C   
1276 O O   . LEU A 154 ? 0.12834 0.18785 0.08281 0.00253  0.00530  0.02853  1160 LEU A O   
1277 C CB  . LEU A 154 ? 0.12909 0.17315 0.09017 -0.01437 0.00167  0.00480  1160 LEU A CB  
1278 C CG  . LEU A 154 ? 0.12853 0.18061 0.09582 -0.02109 -0.00416 0.00492  1160 LEU A CG  
1279 C CD1 . LEU A 154 ? 0.14450 0.19621 0.09500 -0.00519 -0.00166 0.01185  1160 LEU A CD1 
1280 C CD2 . LEU A 154 ? 0.14592 0.19936 0.10399 -0.02492 -0.00015 -0.00040 1160 LEU A CD2 
1281 N N   . PRO A 155 ? 0.13063 0.16392 0.08269 -0.01275 0.00363  0.01605  1161 PRO A N   
1282 C CA  . PRO A 155 ? 0.14414 0.18736 0.08241 -0.00646 0.00380  0.00893  1161 PRO A CA  
1283 C C   . PRO A 155 ? 0.13854 0.16779 0.08816 0.00259  0.00719  0.01197  1161 PRO A C   
1284 O O   . PRO A 155 ? 0.13017 0.17931 0.11312 -0.01442 -0.00054 0.02131  1161 PRO A O   
1285 C CB  . PRO A 155 ? 0.16671 0.23533 0.08011 -0.01353 -0.00577 0.00803  1161 PRO A CB  
1286 C CG  . PRO A 155 ? 0.18133 0.23676 0.07926 0.00004  -0.01308 0.00464  1161 PRO A CG  
1287 C CD  . PRO A 155 ? 0.14380 0.19103 0.07812 0.00133  -0.01632 0.01429  1161 PRO A CD  
1288 N N   . GLU A 156 ? 0.14061 0.18645 0.08152 0.00383  0.01101  0.01428  1162 GLU A N   
1289 C CA  . GLU A 156 ? 0.12650 0.21715 0.08791 -0.00318 0.01182  0.02071  1162 GLU A CA  
1290 C C   . GLU A 156 ? 0.14522 0.22846 0.10308 -0.00267 0.01012  0.02403  1162 GLU A C   
1291 O O   . GLU A 156 ? 0.14199 0.31235 0.10995 -0.00929 0.00863  0.01628  1162 GLU A O   
1292 C CB  . GLU A 156 ? 0.14531 0.20869 0.07999 0.00643  0.00519  0.01851  1162 GLU A CB  
1293 C CG  . GLU A 156 ? 0.14288 0.20941 0.07744 -0.00309 0.01275  0.01754  1162 GLU A CG  
1294 C CD  . GLU A 156 ? 0.16483 0.24135 0.08248 -0.03037 0.01047  -0.00156 1162 GLU A CD  
1295 O OE1 . GLU A 156 ? 0.24614 0.28273 0.09023 0.07739  -0.00865 0.01882  1162 GLU A OE1 
1296 O OE2 . GLU A 156 ? 0.16663 0.33602 0.09624 -0.05470 0.01579  -0.03661 1162 GLU A OE2 
1297 N N   . GLU A 157 ? 0.15145 0.21059 0.11761 0.00889  0.03579  0.01254  1163 GLU A N   
1298 C CA  . GLU A 157 ? 0.18620 0.23000 0.13602 -0.00237 0.05722  0.00907  1163 GLU A CA  
1299 C C   . GLU A 157 ? 0.15214 0.23411 0.12233 0.00359  0.05703  0.01645  1163 GLU A C   
1300 O O   . GLU A 157 ? 0.16206 0.25637 0.14082 0.01845  0.05245  0.02423  1163 GLU A O   
1301 C CB  . GLU A 157 ? 0.24607 0.26840 0.16403 0.00163  0.08405  0.00493  1163 GLU A CB  
1302 C CG  . GLU A 157 ? 0.34441 0.35987 0.18881 0.04844  0.05642  0.00961  1163 GLU A CG  
1303 C CD  . GLU A 157 ? 0.40214 0.39787 0.20200 0.08821  0.03565  0.01353  1163 GLU A CD  
1304 O OE1 . GLU A 157 ? 0.33125 0.34457 0.20308 0.01937  0.01989  0.00068  1163 GLU A OE1 
1305 O OE2 . GLU A 157 ? 0.47370 0.47959 0.21304 0.14976  0.03619  0.01985  1163 GLU A OE2 
1306 N N   . ASP A 158 ? 0.15662 0.20049 0.10598 0.00659  0.03489  0.00539  1164 ASP A N   
1307 C CA  . ASP A 158 ? 0.14892 0.21431 0.10552 0.00186  0.02214  0.00436  1164 ASP A CA  
1308 C C   . ASP A 158 ? 0.12609 0.22367 0.10995 -0.00756 0.01025  0.00994  1164 ASP A C   
1309 O O   . ASP A 158 ? 0.12594 0.20430 0.10495 -0.00511 0.01363  0.00736  1164 ASP A O   
1310 C CB  . ASP A 158 ? 0.15873 0.21230 0.10525 -0.00044 0.01992  0.00673  1164 ASP A CB  
1311 C CG  . ASP A 158 ? 0.16532 0.24259 0.10466 -0.00447 0.01007  0.00735  1164 ASP A CG  
1312 O OD1 . ASP A 158 ? 0.15945 0.24673 0.11358 -0.01162 0.02672  0.02060  1164 ASP A OD1 
1313 O OD2 . ASP A 158 ? 0.20846 0.26264 0.10802 -0.00913 -0.00301 0.02531  1164 ASP A OD2 
1314 N N   . PRO A 159 ? 0.13984 0.23146 0.12391 0.00712  0.00327  0.00076  1165 PRO A N   
1315 C CA  . PRO A 159 ? 0.14907 0.22592 0.12480 0.01211  -0.01739 -0.00448 1165 PRO A CA  
1316 C C   . PRO A 159 ? 0.13469 0.21899 0.12352 -0.00875 -0.00823 0.00768  1165 PRO A C   
1317 O O   . PRO A 159 ? 0.15709 0.21094 0.13118 -0.00871 -0.00649 0.00401  1165 PRO A O   
1318 C CB  . PRO A 159 ? 0.18767 0.27145 0.13755 0.04058  -0.03501 -0.01575 1165 PRO A CB  
1319 C CG  . PRO A 159 ? 0.17931 0.30064 0.14422 0.02295  -0.02853 -0.02033 1165 PRO A CG  
1320 C CD  . PRO A 159 ? 0.14512 0.27637 0.13740 0.01776  -0.01694 -0.00953 1165 PRO A CD  
1321 N N   . ASN A 160 ? 0.12863 0.22849 0.12357 -0.01615 -0.00441 0.02079  1166 ASN A N   
1322 C CA  . ASN A 160 ? 0.13147 0.21775 0.12922 -0.03640 -0.00271 0.02652  1166 ASN A CA  
1323 C C   . ASN A 160 ? 0.13660 0.20280 0.11508 -0.00021 -0.00309 0.02208  1166 ASN A C   
1324 O O   . ASN A 160 ? 0.15695 0.20873 0.11476 -0.01692 0.00002  0.03224  1166 ASN A O   
1325 C CB  . ASN A 160 ? 0.14472 0.28026 0.15045 -0.03940 0.00860  0.03360  1166 ASN A CB  
1326 C CG  . ASN A 160 ? 0.16012 0.33186 0.16863 -0.05118 0.00586  0.02974  1166 ASN A CG  
1327 O OD1 . ASN A 160 ? 0.18224 0.32292 0.18147 -0.05597 -0.01134 0.01169  1166 ASN A OD1 
1328 N ND2 . ASN A 160 ? 0.16839 0.40128 0.17839 -0.00947 0.00165  0.02303  1166 ASN A ND2 
1329 N N   . ALA A 161 ? 0.13473 0.19160 0.10518 -0.02158 -0.00308 0.01150  1167 ALA A N   
1330 C CA  . ALA A 161 ? 0.13833 0.18832 0.09964 -0.02609 0.00244  0.00940  1167 ALA A CA  
1331 C C   . ALA A 161 ? 0.13774 0.17227 0.08537 -0.02263 -0.00424 0.00325  1167 ALA A C   
1332 O O   . ALA A 161 ? 0.14288 0.20756 0.09770 -0.01823 -0.01482 -0.00406 1167 ALA A O   
1333 C CB  . ALA A 161 ? 0.14874 0.18334 0.10579 -0.01916 0.00760  0.01416  1167 ALA A CB  
1334 N N   . THR A 162 ? 0.13203 0.17260 0.08088 -0.02036 -0.00087 0.01089  1168 THR A N   
1335 C CA  . THR A 162 ? 0.13903 0.16617 0.08294 -0.01905 -0.00668 0.01846  1168 THR A CA  
1336 C C   . THR A 162 ? 0.13400 0.14875 0.07457 -0.01587 -0.00874 0.00745  1168 THR A C   
1337 O O   . THR A 162 ? 0.13408 0.16012 0.08455 -0.01456 -0.00307 -0.00393 1168 THR A O   
1338 C CB  . THR A 162 ? 0.15832 0.16295 0.09512 -0.03045 0.00520  0.02683  1168 THR A CB  
1339 O OG1 . THR A 162 ? 0.19850 0.21392 0.12162 -0.03233 0.02884  0.04310  1168 THR A OG1 
1340 C CG2 . THR A 162 ? 0.17772 0.16319 0.09406 -0.01836 -0.00219 0.02214  1168 THR A CG2 
1341 N N   . HIS A 163 ? 0.13141 0.14442 0.06940 -0.00541 -0.00837 0.00720  1169 HIS A N   
1342 C CA  . HIS A 163 ? 0.12584 0.14278 0.07385 -0.01545 -0.00398 0.00974  1169 HIS A CA  
1343 C C   . HIS A 163 ? 0.13725 0.13267 0.07020 -0.01320 -0.00325 0.01355  1169 HIS A C   
1344 O O   . HIS A 163 ? 0.14439 0.14333 0.07464 -0.00248 -0.01488 0.00083  1169 HIS A O   
1345 C CB  . HIS A 163 ? 0.13110 0.14079 0.06534 -0.00736 -0.00794 0.01397  1169 HIS A CB  
1346 C CG  . HIS A 163 ? 0.13850 0.13602 0.07052 -0.02003 -0.01027 0.00315  1169 HIS A CG  
1347 N ND1 . HIS A 163 ? 0.12625 0.15817 0.07965 -0.00658 -0.00356 0.01749  1169 HIS A ND1 
1348 C CD2 . HIS A 163 ? 0.12917 0.16730 0.07873 -0.00807 -0.01342 0.00695  1169 HIS A CD2 
1349 C CE1 . HIS A 163 ? 0.12953 0.16104 0.08460 -0.01323 -0.00829 0.01580  1169 HIS A CE1 
1350 N NE2 . HIS A 163 ? 0.12892 0.16196 0.08349 -0.00530 -0.00234 0.00893  1169 HIS A NE2 
1351 N N   . ILE A 164 ? 0.12017 0.14405 0.06805 -0.01478 -0.01317 0.01293  1170 ILE A N   
1352 C CA  . ILE A 164 ? 0.12493 0.15033 0.06503 0.00389  -0.00569 0.01362  1170 ILE A CA  
1353 C C   . ILE A 164 ? 0.12885 0.15492 0.06210 -0.00011 -0.01323 0.01010  1170 ILE A C   
1354 O O   . ILE A 164 ? 0.13684 0.16287 0.06605 -0.01886 -0.00146 0.00618  1170 ILE A O   
1355 C CB  . ILE A 164 ? 0.13710 0.17052 0.06511 -0.00522 -0.00475 0.01827  1170 ILE A CB  
1356 C CG1 . ILE A 164 ? 0.15958 0.18675 0.06840 -0.00307 0.00132  0.01801  1170 ILE A CG1 
1357 C CG2 . ILE A 164 ? 0.15625 0.18690 0.07034 0.00901  -0.01205 0.01994  1170 ILE A CG2 
1358 C CD1 . ILE A 164 ? 0.18649 0.22538 0.07389 0.01286  0.00415  0.02356  1170 ILE A CD1 
1359 N N   . MET A 165 ? 0.13259 0.15788 0.06046 0.00057  -0.00956 0.00783  1171 MET A N   
1360 C CA  . MET A 165 ? 0.13320 0.16359 0.06244 -0.00030 -0.00990 0.01546  1171 MET A CA  
1361 C C   . MET A 165 ? 0.12871 0.17582 0.06797 -0.00279 -0.00890 0.01773  1171 MET A C   
1362 O O   . MET A 165 ? 0.15443 0.16249 0.08303 0.01217  -0.01218 0.00658  1171 MET A O   
1363 C CB  . MET A 165 ? 0.13757 0.18443 0.06400 0.00821  -0.01469 0.01558  1171 MET A CB  
1364 C CG  . MET A 165 ? 0.12628 0.19012 0.07178 0.01663  -0.01734 0.02080  1171 MET A CG  
1365 S SD  . MET A 165 ? 0.12701 0.16716 0.06895 -0.00324 -0.01309 0.02068  1171 MET A SD  
1366 C CE  . MET A 165 ? 0.13563 0.22023 0.08237 -0.03073 -0.02097 0.02038  1171 MET A CE  
1367 N N   . ILE A 166 ? 0.11956 0.18767 0.06743 0.01174  -0.00661 0.01817  1172 ILE A N   
1368 C CA  . ILE A 166 ? 0.12858 0.19033 0.06353 0.01314  -0.01139 0.02343  1172 ILE A CA  
1369 C C   . ILE A 166 ? 0.12094 0.20089 0.06290 0.01979  -0.02363 0.01124  1172 ILE A C   
1370 O O   . ILE A 166 ? 0.13501 0.20636 0.07270 0.00179  -0.01663 0.01166  1172 ILE A O   
1371 C CB  . ILE A 166 ? 0.13686 0.22492 0.06501 0.02662  -0.01203 0.02075  1172 ILE A CB  
1372 C CG1 . ILE A 166 ? 0.16223 0.21965 0.06038 0.00382  -0.01442 0.01984  1172 ILE A CG1 
1373 C CG2 . ILE A 166 ? 0.13731 0.24347 0.07244 0.04098  -0.00761 0.02665  1172 ILE A CG2 
1374 C CD1 . ILE A 166 ? 0.15300 0.21802 0.06565 0.01302  -0.01736 0.00716  1172 ILE A CD1 
1375 N N   . ALA A 167 ? 0.12773 0.21431 0.06579 0.03071  -0.01515 0.01101  1173 ALA A N   
1376 C CA  . ALA A 167 ? 0.13008 0.21427 0.06944 0.02154  -0.00666 0.00930  1173 ALA A CA  
1377 C C   . ALA A 167 ? 0.12828 0.25169 0.07334 0.03740  -0.01112 0.01338  1173 ALA A C   
1378 O O   . ALA A 167 ? 0.13552 0.25666 0.07976 0.03945  -0.01182 0.00824  1173 ALA A O   
1379 C CB  . ALA A 167 ? 0.12904 0.20937 0.07450 0.02355  -0.00950 0.00840  1173 ALA A CB  
1380 N N   . THR A 168 ? 0.11421 0.28054 0.08198 0.02120  -0.01369 0.00757  1174 THR A N   
1381 C CA  . THR A 168 ? 0.12163 0.31160 0.08911 0.03854  -0.01329 0.01715  1174 THR A CA  
1382 C C   . THR A 168 ? 0.12734 0.29203 0.08508 0.03166  -0.01642 0.02060  1174 THR A C   
1383 O O   . THR A 168 ? 0.13190 0.28897 0.07905 0.03256  -0.01182 0.01430  1174 THR A O   
1384 C CB  . THR A 168 ? 0.15400 0.37457 0.10308 0.06429  -0.00890 0.01506  1174 THR A CB  
1385 O OG1 . THR A 168 ? 0.13788 0.39310 0.10153 0.01767  -0.00873 0.00884  1174 THR A OG1 
1386 C CG2 . THR A 168 ? 0.18016 0.38233 0.11259 0.07112  -0.01707 0.02350  1174 THR A CG2 
1387 N N   . GLY A 169 ? 0.13639 0.27887 0.07747 0.04600  -0.00636 0.01829  1175 GLY A N   
1388 C CA  . GLY A 169 ? 0.14093 0.27559 0.07658 0.04042  -0.00460 0.02301  1175 GLY A CA  
1389 C C   . GLY A 169 ? 0.12640 0.26848 0.07287 0.02215  -0.00710 0.01431  1175 GLY A C   
1390 O O   . GLY A 169 ? 0.13522 0.24084 0.07571 0.02014  -0.00763 0.01030  1175 GLY A O   
1391 N N   . THR A 170 ? 0.14004 0.25584 0.07190 0.02531  0.00122  0.03064  1176 THR A N   
1392 C CA  . THR A 170 ? 0.11113 0.23991 0.07615 0.01350  -0.00260 0.03068  1176 THR A CA  
1393 C C   . THR A 170 ? 0.10021 0.23107 0.07962 -0.00045 -0.00604 0.02152  1176 THR A C   
1394 O O   . THR A 170 ? 0.10532 0.22342 0.08563 0.00453  -0.00359 0.02274  1176 THR A O   
1395 C CB  . THR A 170 ? 0.11014 0.26661 0.08006 0.00997  0.00311  0.01952  1176 THR A CB  
1396 O OG1 . THR A 170 ? 0.10817 0.26977 0.09044 -0.00395 -0.00665 0.01497  1176 THR A OG1 
1397 C CG2 . THR A 170 ? 0.11660 0.29198 0.08464 0.01796  0.00472  0.01781  1176 THR A CG2 
1398 N N   . GLY A 171 ? 0.10788 0.23737 0.07906 0.01305  -0.00594 0.01719  1177 GLY A N   
1399 C CA  . GLY A 171 ? 0.11475 0.24586 0.07265 0.01006  -0.00710 0.00555  1177 GLY A CA  
1400 C C   . GLY A 171 ? 0.10875 0.22693 0.06259 0.01858  -0.01311 0.00985  1177 GLY A C   
1401 O O   . GLY A 171 ? 0.11365 0.21441 0.06558 -0.00035 -0.00564 0.01728  1177 GLY A O   
1402 N N   . VAL A 172 ? 0.11316 0.22037 0.06424 0.01174  -0.00758 0.01485  1178 VAL A N   
1403 C CA  . VAL A 172 ? 0.12128 0.19571 0.08193 0.01490  -0.00444 0.02744  1178 VAL A CA  
1404 C C   . VAL A 172 ? 0.10687 0.17958 0.06929 0.00590  -0.01019 0.00692  1178 VAL A C   
1405 O O   . VAL A 172 ? 0.11949 0.18158 0.06894 0.00633  -0.00834 0.01208  1178 VAL A O   
1406 C CB  . VAL A 172 ? 0.13749 0.20248 0.11010 0.01804  -0.00661 0.01579  1178 VAL A CB  
1407 C CG1 . VAL A 172 ? 0.15896 0.21255 0.11323 0.04342  -0.01441 -0.00981 1178 VAL A CG1 
1408 C CG2 . VAL A 172 ? 0.15709 0.25264 0.13162 0.02018  -0.01251 0.01758  1178 VAL A CG2 
1409 N N   . ALA A 173 ? 0.11745 0.18587 0.06540 0.00810  -0.00141 0.01283  1179 ALA A N   
1410 C CA  . ALA A 173 ? 0.11927 0.17854 0.07068 -0.00042 0.00087  0.01307  1179 ALA A CA  
1411 C C   . ALA A 173 ? 0.09629 0.16191 0.06820 -0.00434 -0.00645 0.01314  1179 ALA A C   
1412 O O   . ALA A 173 ? 0.10932 0.17996 0.05978 -0.00967 0.00025  0.01300  1179 ALA A O   
1413 C CB  . ALA A 173 ? 0.11250 0.19495 0.07441 -0.01150 0.00560  0.01143  1179 ALA A CB  
1414 N N   . PRO A 174 ? 0.10123 0.17529 0.06810 -0.00281 -0.00247 0.01936  1180 PRO A N   
1415 C CA  . PRO A 174 ? 0.10527 0.17373 0.06746 -0.01123 -0.00771 0.01274  1180 PRO A CA  
1416 C C   . PRO A 174 ? 0.10076 0.15931 0.06131 -0.00699 -0.01081 0.01064  1180 PRO A C   
1417 O O   . PRO A 174 ? 0.11450 0.15364 0.07033 -0.00859 -0.00490 0.01389  1180 PRO A O   
1418 C CB  . PRO A 174 ? 0.10893 0.17190 0.07747 -0.01468 -0.01229 -0.00180 1180 PRO A CB  
1419 C CG  . PRO A 174 ? 0.10603 0.19331 0.07556 -0.00535 -0.00854 0.00851  1180 PRO A CG  
1420 C CD  . PRO A 174 ? 0.10225 0.18508 0.06898 -0.00485 -0.01419 0.00601  1180 PRO A CD  
1421 N N   . PHE A 175 ? 0.11391 0.16772 0.05633 0.00711  -0.01480 0.01909  1181 PHE A N   
1422 C CA  . PHE A 175 ? 0.11456 0.14789 0.05487 -0.01220 -0.00685 0.02133  1181 PHE A CA  
1423 C C   . PHE A 175 ? 0.11006 0.15184 0.05898 0.00312  -0.00881 0.02222  1181 PHE A C   
1424 O O   . PHE A 175 ? 0.11431 0.15437 0.06452 0.00106  -0.00107 0.01357  1181 PHE A O   
1425 C CB  . PHE A 175 ? 0.12139 0.16389 0.05719 0.00293  -0.01616 0.00943  1181 PHE A CB  
1426 C CG  . PHE A 175 ? 0.11711 0.16208 0.05992 -0.00882 -0.00594 0.02438  1181 PHE A CG  
1427 C CD1 . PHE A 175 ? 0.12671 0.16734 0.06233 -0.00640 -0.01022 0.00993  1181 PHE A CD1 
1428 C CD2 . PHE A 175 ? 0.12484 0.18896 0.07498 0.00059  -0.00842 0.00771  1181 PHE A CD2 
1429 C CE1 . PHE A 175 ? 0.12824 0.18846 0.06583 -0.01296 -0.01548 0.01034  1181 PHE A CE1 
1430 C CE2 . PHE A 175 ? 0.11773 0.21026 0.07562 -0.00057 -0.00813 0.01330  1181 PHE A CE2 
1431 C CZ  . PHE A 175 ? 0.10832 0.20994 0.06634 -0.01693 -0.00275 0.01860  1181 PHE A CZ  
1432 N N   . ARG A 176 ? 0.11553 0.16616 0.05659 0.00416  -0.01149 0.01679  1182 ARG A N   
1433 C CA  . ARG A 176 ? 0.10980 0.15645 0.05509 0.00147  -0.00800 0.01149  1182 ARG A CA  
1434 C C   . ARG A 176 ? 0.10651 0.15160 0.04901 -0.00642 -0.00364 0.01055  1182 ARG A C   
1435 O O   . ARG A 176 ? 0.11459 0.15417 0.05812 -0.00867 -0.00232 0.01378  1182 ARG A O   
1436 C CB  . ARG A 176 ? 0.12432 0.17629 0.05681 0.01167  -0.01192 0.00455  1182 ARG A CB  
1437 C CG  . ARG A 176 ? 0.12613 0.16075 0.05590 0.00131  -0.00001 0.00837  1182 ARG A CG  
1438 C CD  . ARG A 176 ? 0.11439 0.17402 0.05348 0.01428  -0.01096 0.00370  1182 ARG A CD  
1439 N NE  . ARG A 176 ? 0.11882 0.16906 0.06806 0.01133  -0.00655 0.00908  1182 ARG A NE  
1440 C CZ  . ARG A 176 ? 0.11680 0.16906 0.06811 0.00429  -0.00028 0.00756  1182 ARG A CZ  
1441 N NH1 . ARG A 176 ? 0.10758 0.17560 0.07862 0.01499  -0.00522 0.00922  1182 ARG A NH1 
1442 N NH2 . ARG A 176 ? 0.13871 0.18349 0.06362 -0.00507 -0.00560 0.00329  1182 ARG A NH2 
1443 N N   . GLY A 177 ? 0.11369 0.14253 0.05761 0.00173  -0.00090 0.01305  1183 GLY A N   
1444 C CA  . GLY A 177 ? 0.11713 0.14053 0.06402 0.00562  0.00604  0.01735  1183 GLY A CA  
1445 C C   . GLY A 177 ? 0.10757 0.14865 0.06238 0.00323  -0.00801 0.01472  1183 GLY A C   
1446 O O   . GLY A 177 ? 0.11212 0.16247 0.06568 -0.00176 -0.00924 0.01053  1183 GLY A O   
1447 N N   . TYR A 178 ? 0.11252 0.15596 0.05749 -0.00892 -0.00727 0.01283  1184 TYR A N   
1448 C CA  . TYR A 178 ? 0.10563 0.16148 0.05739 -0.01638 -0.00896 0.01426  1184 TYR A CA  
1449 C C   . TYR A 178 ? 0.10672 0.15100 0.05612 -0.01663 -0.01066 0.01207  1184 TYR A C   
1450 O O   . TYR A 178 ? 0.11085 0.15835 0.06482 -0.00603 -0.00496 0.01644  1184 TYR A O   
1451 C CB  . TYR A 178 ? 0.13519 0.15006 0.05925 -0.00053 -0.00718 0.01332  1184 TYR A CB  
1452 C CG  . TYR A 178 ? 0.10730 0.15618 0.06502 -0.00999 -0.00429 0.00946  1184 TYR A CG  
1453 C CD1 . TYR A 178 ? 0.11370 0.15488 0.06647 -0.01611 -0.00586 0.00710  1184 TYR A CD1 
1454 C CD2 . TYR A 178 ? 0.12898 0.15692 0.07156 -0.00506 -0.01371 0.01579  1184 TYR A CD2 
1455 C CE1 . TYR A 178 ? 0.12291 0.17320 0.06812 -0.00317 -0.00356 0.01685  1184 TYR A CE1 
1456 C CE2 . TYR A 178 ? 0.13909 0.16976 0.07935 -0.01980 -0.01524 0.00985  1184 TYR A CE2 
1457 C CZ  . TYR A 178 ? 0.12450 0.15994 0.07994 -0.01398 -0.01163 0.01170  1184 TYR A CZ  
1458 O OH  . TYR A 178 ? 0.16103 0.16818 0.08920 -0.02868 -0.03016 0.00293  1184 TYR A OH  
1459 N N   . LEU A 179 ? 0.12308 0.14248 0.06421 0.00058  -0.01625 0.00779  1185 LEU A N   
1460 C CA  . LEU A 179 ? 0.11971 0.13900 0.06327 -0.00540 -0.01343 0.01726  1185 LEU A CA  
1461 C C   . LEU A 179 ? 0.11959 0.13930 0.06699 -0.00945 -0.00091 0.01618  1185 LEU A C   
1462 O O   . LEU A 179 ? 0.12969 0.14502 0.07388 -0.01458 -0.01175 0.01595  1185 LEU A O   
1463 C CB  . LEU A 179 ? 0.12811 0.14722 0.07050 -0.00033 -0.01804 0.01665  1185 LEU A CB  
1464 C CG  . LEU A 179 ? 0.13290 0.15321 0.07270 0.00406  -0.01189 0.02661  1185 LEU A CG  
1465 C CD1 . LEU A 179 ? 0.13772 0.18034 0.08584 0.00763  -0.01909 0.03423  1185 LEU A CD1 
1466 C CD2 . LEU A 179 ? 0.16320 0.17146 0.06832 0.00184  -0.00342 0.02816  1185 LEU A CD2 
1467 N N   . ARG A 180 ? 0.11654 0.15097 0.06185 -0.00405 -0.01159 0.01657  1186 ARG A N   
1468 C CA  . ARG A 180 ? 0.12250 0.13981 0.06553 -0.00777 -0.00978 0.01532  1186 ARG A CA  
1469 C C   . ARG A 180 ? 0.11548 0.13736 0.06967 -0.01091 -0.00748 0.02166  1186 ARG A C   
1470 O O   . ARG A 180 ? 0.11218 0.16198 0.07584 -0.01664 -0.01389 0.01582  1186 ARG A O   
1471 C CB  . ARG A 180 ? 0.11944 0.15638 0.06554 -0.00469 -0.01132 0.01319  1186 ARG A CB  
1472 C CG  . ARG A 180 ? 0.13355 0.15133 0.06637 -0.00137 -0.00412 0.01491  1186 ARG A CG  
1473 C CD  . ARG A 180 ? 0.14343 0.17162 0.07430 0.00271  0.00681  0.00512  1186 ARG A CD  
1474 N NE  . ARG A 180 ? 0.13876 0.16084 0.07571 0.00580  -0.01019 0.00962  1186 ARG A NE  
1475 C CZ  . ARG A 180 ? 0.13536 0.15014 0.08360 -0.00131 -0.01135 0.01208  1186 ARG A CZ  
1476 N NH1 . ARG A 180 ? 0.14397 0.15524 0.08634 0.00001  -0.01339 0.02175  1186 ARG A NH1 
1477 N NH2 . ARG A 180 ? 0.14446 0.15675 0.08983 0.00469  -0.00476 0.00445  1186 ARG A NH2 
1478 N N   . ARG A 181 ? 0.10708 0.14940 0.07288 0.00171  -0.00129 0.01603  1187 ARG A N   
1479 C CA  . ARG A 181 ? 0.11654 0.14410 0.07737 -0.00740 -0.00498 0.01396  1187 ARG A CA  
1480 C C   . ARG A 181 ? 0.10854 0.14710 0.07851 -0.01493 -0.00474 0.01358  1187 ARG A C   
1481 O O   . ARG A 181 ? 0.10420 0.16662 0.08706 -0.01152 0.00083  0.02195  1187 ARG A O   
1482 C CB  . ARG A 181 ? 0.11182 0.14132 0.07989 -0.00651 -0.01518 0.01520  1187 ARG A CB  
1483 C CG  . ARG A 181 ? 0.10546 0.15920 0.08307 0.00073  -0.00721 0.01022  1187 ARG A CG  
1484 C CD  . ARG A 181 ? 0.10470 0.14842 0.08175 -0.00440 0.00426  0.00444  1187 ARG A CD  
1485 N NE  . ARG A 181 ? 0.11584 0.15439 0.07858 -0.00346 0.00102  0.01245  1187 ARG A NE  
1486 C CZ  . ARG A 181 ? 0.11399 0.15555 0.07550 -0.00108 -0.00479 0.01153  1187 ARG A CZ  
1487 N NH1 . ARG A 181 ? 0.11729 0.17220 0.06982 -0.00384 -0.00768 0.01551  1187 ARG A NH1 
1488 N NH2 . ARG A 181 ? 0.11888 0.17493 0.08526 0.01517  0.00235  0.01247  1187 ARG A NH2 
1489 N N   . MET A 182 ? 0.12397 0.13721 0.07876 -0.00845 -0.00369 0.03046  1188 MET A N   
1490 C CA  . MET A 182 ? 0.12477 0.16216 0.08082 -0.01489 -0.01136 0.02574  1188 MET A CA  
1491 C C   . MET A 182 ? 0.12660 0.15391 0.07978 -0.01434 -0.00275 0.02428  1188 MET A C   
1492 O O   . MET A 182 ? 0.12540 0.16946 0.08797 -0.01781 -0.00550 0.02998  1188 MET A O   
1493 C CB  . MET A 182 ? 0.13989 0.15679 0.08566 -0.02102 -0.01764 0.02244  1188 MET A CB  
1494 C CG  . MET A 182 ? 0.12406 0.17134 0.08651 -0.01849 -0.02159 0.02249  1188 MET A CG  
1495 S SD  . MET A 182 ? 0.14854 0.17352 0.08639 -0.00934 -0.02088 0.02809  1188 MET A SD  
1496 C CE  . MET A 182 ? 0.16352 0.20964 0.09758 0.00711  -0.01125 -0.00587 1188 MET A CE  
1497 N N   . PHE A 183 ? 0.13254 0.14607 0.07772 -0.01006 -0.02034 0.01503  1189 PHE A N   
1498 C CA  . PHE A 183 ? 0.14511 0.15417 0.08374 -0.01379 -0.01810 0.02079  1189 PHE A CA  
1499 C C   . PHE A 183 ? 0.12826 0.16641 0.08894 -0.02998 -0.02030 0.01318  1189 PHE A C   
1500 O O   . PHE A 183 ? 0.16139 0.19124 0.09443 -0.03165 -0.02079 0.02587  1189 PHE A O   
1501 C CB  . PHE A 183 ? 0.14736 0.16042 0.08606 -0.00324 -0.01453 0.02102  1189 PHE A CB  
1502 C CG  . PHE A 183 ? 0.14847 0.14661 0.08596 -0.01627 -0.01807 0.02422  1189 PHE A CG  
1503 C CD1 . PHE A 183 ? 0.17358 0.14200 0.08626 -0.00537 -0.01595 0.01970  1189 PHE A CD1 
1504 C CD2 . PHE A 183 ? 0.17323 0.15465 0.09099 -0.01385 -0.02893 0.02803  1189 PHE A CD2 
1505 C CE1 . PHE A 183 ? 0.17433 0.14172 0.08844 -0.01712 -0.01203 0.02224  1189 PHE A CE1 
1506 C CE2 . PHE A 183 ? 0.17496 0.17667 0.09514 -0.02868 -0.02487 0.02421  1189 PHE A CE2 
1507 C CZ  . PHE A 183 ? 0.18325 0.15575 0.09189 -0.02630 -0.02343 0.01891  1189 PHE A CZ  
1508 N N   . MET A 184 ? 0.13114 0.16338 0.07795 -0.01731 -0.00993 0.02298  1190 MET A N   
1509 C CA  . MET A 184 ? 0.13362 0.16617 0.08350 -0.01985 -0.01093 0.02086  1190 MET A CA  
1510 C C   . MET A 184 ? 0.13568 0.16501 0.08733 -0.02050 -0.00941 0.01492  1190 MET A C   
1511 O O   . MET A 184 ? 0.16224 0.16022 0.09409 -0.02487 -0.02893 0.00865  1190 MET A O   
1512 C CB  . MET A 184 ? 0.14531 0.22783 0.08868 0.00380  -0.01918 0.01720  1190 MET A CB  
1513 C CG  . MET A 184 ? 0.15353 0.18667 0.08986 -0.01539 -0.00994 -0.00119 1190 MET A CG  
1514 S SD  . MET A 184 ? 0.15674 0.18187 0.08034 -0.01007 -0.00531 0.01320  1190 MET A SD  
1515 C CE  . MET A 184 ? 0.17449 0.19734 0.09644 0.00393  -0.01093 0.00287  1190 MET A CE  
1516 N N   . GLU A 185 ? 0.11810 0.15347 0.08487 -0.01275 -0.00875 0.02121  1191 GLU A N   
1517 C CA  . GLU A 185 ? 0.10809 0.17275 0.08492 -0.01637 -0.00972 0.01875  1191 GLU A CA  
1518 C C   . GLU A 185 ? 0.10980 0.17524 0.08378 -0.03098 -0.01146 0.01976  1191 GLU A C   
1519 O O   . GLU A 185 ? 0.11870 0.20303 0.07727 -0.02583 -0.00690 0.02568  1191 GLU A O   
1520 C CB  . GLU A 185 ? 0.10780 0.15773 0.09234 -0.02248 -0.00779 0.02388  1191 GLU A CB  
1521 C CG  . GLU A 185 ? 0.10283 0.15967 0.08915 -0.01220 -0.00400 0.02477  1191 GLU A CG  
1522 C CD  . GLU A 185 ? 0.09201 0.15746 0.08592 0.00127  -0.01419 0.01849  1191 GLU A CD  
1523 O OE1 . GLU A 185 ? 0.11164 0.15542 0.09880 0.00137  -0.00667 -0.00328 1191 GLU A OE1 
1524 O OE2 . GLU A 185 ? 0.10437 0.16135 0.08752 -0.01704 -0.00460 0.02199  1191 GLU A OE2 
1525 N N   . ASP A 186 ? 0.09315 0.21255 0.08783 -0.01814 -0.01253 0.01453  1192 ASP A N   
1526 C CA  . ASP A 186 ? 0.10955 0.20340 0.08765 -0.02420 -0.01249 0.00798  1192 ASP A CA  
1527 C C   . ASP A 186 ? 0.10701 0.21872 0.08805 -0.01889 -0.00736 0.01720  1192 ASP A C   
1528 O O   . ASP A 186 ? 0.13743 0.23242 0.08919 0.00409  -0.01156 0.02003  1192 ASP A O   
1529 C CB  . ASP A 186 ? 0.10529 0.26341 0.09681 -0.03822 -0.02427 0.00374  1192 ASP A CB  
1530 C CG  . ASP A 186 ? 0.12169 0.28905 0.11033 -0.03544 -0.02621 0.01296  1192 ASP A CG  
1531 O OD1 . ASP A 186 ? 0.10832 0.32691 0.11395 -0.03131 -0.01377 0.01340  1192 ASP A OD1 
1532 O OD2 . ASP A 186 ? 0.12146 0.33219 0.12165 -0.03570 -0.03397 0.01736  1192 ASP A OD2 
1533 N N   . VAL A 187 ? 0.11548 0.20385 0.08944 -0.02506 -0.01412 0.00206  1193 VAL A N   
1534 C CA  . VAL A 187 ? 0.10726 0.22780 0.09831 -0.00046 -0.01139 0.00172  1193 VAL A CA  
1535 C C   . VAL A 187 ? 0.10282 0.23006 0.10627 -0.01146 -0.00487 0.01097  1193 VAL A C   
1536 O O   . VAL A 187 ? 0.10809 0.20073 0.11241 -0.00965 0.00200  0.01393  1193 VAL A O   
1537 C CB  . VAL A 187 ? 0.10909 0.20822 0.10409 -0.02200 -0.00440 -0.00853 1193 VAL A CB  
1538 C CG1 . VAL A 187 ? 0.11573 0.21720 0.10535 -0.02040 -0.00477 -0.00356 1193 VAL A CG1 
1539 C CG2 . VAL A 187 ? 0.11517 0.26552 0.11472 -0.03833 0.00561  -0.00889 1193 VAL A CG2 
1540 N N   . PRO A 188 ? 0.09959 0.26630 0.11830 -0.00206 -0.02083 0.00691  1194 PRO A N   
1541 C CA  . PRO A 188 ? 0.10629 0.30224 0.13406 -0.00211 -0.00645 0.01406  1194 PRO A CA  
1542 C C   . PRO A 188 ? 0.11719 0.26747 0.12973 -0.00020 0.00700  0.02900  1194 PRO A C   
1543 O O   . PRO A 188 ? 0.14864 0.28821 0.14154 -0.00882 0.02567  0.03519  1194 PRO A O   
1544 C CB  . PRO A 188 ? 0.12492 0.33956 0.14291 0.02410  -0.01906 0.01087  1194 PRO A CB  
1545 C CG  . PRO A 188 ? 0.14872 0.36772 0.13777 0.04623  -0.03569 0.00418  1194 PRO A CG  
1546 C CD  . PRO A 188 ? 0.13101 0.33694 0.12451 0.05482  -0.03070 0.01189  1194 PRO A CD  
1547 N N   . ASN A 189 ? 0.15056 0.22905 0.11970 0.01980  -0.00693 0.02830  1195 ASN A N   
1548 C CA  . ASN A 189 ? 0.18070 0.22963 0.12091 0.02361  0.00736  0.02665  1195 ASN A CA  
1549 C C   . ASN A 189 ? 0.20960 0.22168 0.11225 0.02298  -0.00355 0.01293  1195 ASN A C   
1550 O O   . ASN A 189 ? 0.26433 0.24509 0.11553 0.04287  -0.00883 -0.00736 1195 ASN A O   
1551 C CB  . ASN A 189 ? 0.15857 0.24289 0.13028 0.01669  0.01467  0.02111  1195 ASN A CB  
1552 C CG  . ASN A 189 ? 0.14676 0.21822 0.12203 0.00689  0.00818  0.01445  1195 ASN A CG  
1553 O OD1 . ASN A 189 ? 0.17333 0.25020 0.11508 -0.00615 0.00893  0.00944  1195 ASN A OD1 
1554 N ND2 . ASN A 189 ? 0.17777 0.23952 0.12456 0.02060  0.00266  0.02646  1195 ASN A ND2 
1555 N N   . TYR A 190 ? 0.16967 0.22875 0.10012 -0.00339 -0.00576 0.01790  1196 TYR A N   
1556 C CA  . TYR A 190 ? 0.14483 0.22640 0.09614 -0.02340 -0.01172 0.02101  1196 TYR A CA  
1557 C C   . TYR A 190 ? 0.12677 0.20778 0.09348 -0.01405 -0.00088 0.01399  1196 TYR A C   
1558 O O   . TYR A 190 ? 0.12639 0.22650 0.09928 -0.00958 -0.00690 0.00270  1196 TYR A O   
1559 C CB  . TYR A 190 ? 0.16088 0.24358 0.09601 -0.03494 -0.01127 0.01956  1196 TYR A CB  
1560 C CG  . TYR A 190 ? 0.15726 0.22146 0.09589 -0.04710 -0.00258 0.01615  1196 TYR A CG  
1561 C CD1 . TYR A 190 ? 0.14788 0.22257 0.09569 -0.03561 -0.01033 0.00453  1196 TYR A CD1 
1562 C CD2 . TYR A 190 ? 0.15089 0.23111 0.09791 -0.05141 0.01083  0.01373  1196 TYR A CD2 
1563 C CE1 . TYR A 190 ? 0.13895 0.20556 0.09624 -0.03832 -0.00178 0.01075  1196 TYR A CE1 
1564 C CE2 . TYR A 190 ? 0.15109 0.20595 0.09603 -0.04335 0.00652  0.00615  1196 TYR A CE2 
1565 C CZ  . TYR A 190 ? 0.13228 0.19668 0.09928 -0.03656 -0.00021 0.01356  1196 TYR A CZ  
1566 O OH  . TYR A 190 ? 0.14238 0.18832 0.10382 -0.02789 -0.00313 0.00983  1196 TYR A OH  
1567 N N   . ARG A 191 ? 0.12314 0.21089 0.09816 0.00435  -0.00318 0.02269  1197 ARG A N   
1568 C CA  . ARG A 191 ? 0.12864 0.22161 0.10127 -0.00772 -0.00867 0.02534  1197 ARG A CA  
1569 C C   . ARG A 191 ? 0.13780 0.22940 0.10072 0.00516  -0.00995 0.02893  1197 ARG A C   
1570 O O   . ARG A 191 ? 0.13527 0.24279 0.10032 -0.01342 -0.00653 0.03582  1197 ARG A O   
1571 C CB  . ARG A 191 ? 0.13192 0.25867 0.10565 0.00217  -0.00696 0.02459  1197 ARG A CB  
1572 C CG  . ARG A 191 ? 0.12099 0.28283 0.11077 0.00499  -0.00517 0.02841  1197 ARG A CG  
1573 C CD  . ARG A 191 ? 0.11735 0.27995 0.11559 -0.01620 -0.00942 0.02336  1197 ARG A CD  
1574 N NE  . ARG A 191 ? 0.11971 0.27839 0.11823 -0.01932 -0.01334 0.03104  1197 ARG A NE  
1575 C CZ  . ARG A 191 ? 0.11124 0.26492 0.12090 -0.02619 -0.01945 0.02121  1197 ARG A CZ  
1576 N NH1 . ARG A 191 ? 0.10895 0.25033 0.12382 -0.01551 -0.01256 0.01628  1197 ARG A NH1 
1577 N NH2 . ARG A 191 ? 0.12424 0.28693 0.12288 -0.02762 -0.03322 0.02102  1197 ARG A NH2 
1578 N N   . PHE A 192 ? 0.15556 0.20509 0.10210 0.01191  -0.02209 0.02118  1198 PHE A N   
1579 C CA  . PHE A 192 ? 0.15252 0.19001 0.10578 0.00079  -0.02020 0.02660  1198 PHE A CA  
1580 C C   . PHE A 192 ? 0.14765 0.19446 0.11556 -0.01563 -0.02431 0.01307  1198 PHE A C   
1581 O O   . PHE A 192 ? 0.19658 0.20012 0.13022 -0.02070 -0.02827 -0.00178 1198 PHE A O   
1582 C CB  . PHE A 192 ? 0.12861 0.19222 0.09943 -0.01686 -0.00946 0.02486  1198 PHE A CB  
1583 C CG  . PHE A 192 ? 0.13131 0.17832 0.09619 -0.02516 -0.00659 0.02475  1198 PHE A CG  
1584 C CD1 . PHE A 192 ? 0.13002 0.17670 0.09771 -0.02756 -0.00968 0.01399  1198 PHE A CD1 
1585 C CD2 . PHE A 192 ? 0.14036 0.16544 0.10364 -0.00568 0.00552  0.03037  1198 PHE A CD2 
1586 C CE1 . PHE A 192 ? 0.13483 0.17102 0.09719 -0.04650 -0.01335 0.02140  1198 PHE A CE1 
1587 C CE2 . PHE A 192 ? 0.14015 0.17706 0.10586 -0.00589 -0.00510 0.02873  1198 PHE A CE2 
1588 C CZ  . PHE A 192 ? 0.14636 0.16982 0.10137 -0.02302 -0.01069 0.03021  1198 PHE A CZ  
1589 N N   . GLY A 193 ? 0.14941 0.20075 0.11972 -0.02903 -0.01543 0.02575  1199 GLY A N   
1590 C CA  . GLY A 193 ? 0.16783 0.20968 0.12474 -0.03917 -0.01704 0.02202  1199 GLY A CA  
1591 C C   . GLY A 193 ? 0.15656 0.19567 0.12102 -0.03984 -0.00772 0.02521  1199 GLY A C   
1592 O O   . GLY A 193 ? 0.17232 0.21949 0.12842 -0.04240 -0.00530 0.02619  1199 GLY A O   
1593 N N   . GLY A 194 ? 0.15191 0.18406 0.11054 -0.02192 -0.01631 0.02154  1200 GLY A N   
1594 C CA  . GLY A 194 ? 0.15170 0.19245 0.10622 -0.02158 -0.01167 0.01860  1200 GLY A CA  
1595 C C   . GLY A 194 ? 0.16149 0.16321 0.09814 -0.01934 -0.01478 0.01538  1200 GLY A C   
1596 O O   . GLY A 194 ? 0.17360 0.17201 0.10931 -0.02466 -0.02591 -0.00344 1200 GLY A O   
1597 N N   . LEU A 195 ? 0.15559 0.15976 0.08618 -0.03015 -0.01423 0.01581  1201 LEU A N   
1598 C CA  . LEU A 195 ? 0.15762 0.14651 0.08440 -0.01780 -0.00991 0.02053  1201 LEU A CA  
1599 C C   . LEU A 195 ? 0.14695 0.13886 0.08205 -0.00842 -0.01325 0.00811  1201 LEU A C   
1600 O O   . LEU A 195 ? 0.15321 0.15401 0.08712 -0.02239 -0.00613 -0.00679 1201 LEU A O   
1601 C CB  . LEU A 195 ? 0.18071 0.15986 0.09342 -0.01957 -0.02250 0.01362  1201 LEU A CB  
1602 C CG  . LEU A 195 ? 0.22499 0.15691 0.10149 -0.00082 -0.03792 0.01244  1201 LEU A CG  
1603 C CD1 . LEU A 195 ? 0.25340 0.15830 0.10841 0.00800  -0.03169 0.01211  1201 LEU A CD1 
1604 C CD2 . LEU A 195 ? 0.26495 0.16779 0.10956 0.01286  -0.03364 0.02247  1201 LEU A CD2 
1605 N N   . ALA A 196 ? 0.14857 0.14006 0.07280 -0.01447 -0.01307 0.00662  1202 ALA A N   
1606 C CA  . ALA A 196 ? 0.14607 0.12932 0.07598 -0.01291 -0.01508 0.01425  1202 ALA A CA  
1607 C C   . ALA A 196 ? 0.16142 0.13089 0.07327 -0.00891 -0.02054 0.00542  1202 ALA A C   
1608 O O   . ALA A 196 ? 0.17983 0.13409 0.09151 -0.00248 -0.02989 0.00144  1202 ALA A O   
1609 C CB  . ALA A 196 ? 0.16734 0.14814 0.07710 -0.00831 -0.02021 0.02498  1202 ALA A CB  
1610 N N   . TRP A 197 ? 0.14409 0.13557 0.06908 0.00095  -0.01047 0.01084  1203 TRP A N   
1611 C CA  . TRP A 197 ? 0.15379 0.13863 0.07286 -0.00834 -0.01231 0.01211  1203 TRP A CA  
1612 C C   . TRP A 197 ? 0.14792 0.14490 0.07271 0.00754  -0.01324 0.00976  1203 TRP A C   
1613 O O   . TRP A 197 ? 0.15557 0.15125 0.07623 -0.00840 -0.00692 -0.00352 1203 TRP A O   
1614 C CB  . TRP A 197 ? 0.16882 0.14842 0.07528 0.00601  -0.01228 0.00684  1203 TRP A CB  
1615 C CG  . TRP A 197 ? 0.18955 0.14174 0.07321 0.00607  -0.01097 0.01500  1203 TRP A CG  
1616 C CD1 . TRP A 197 ? 0.20668 0.14281 0.08204 0.01685  -0.01892 0.01894  1203 TRP A CD1 
1617 C CD2 . TRP A 197 ? 0.21481 0.13667 0.07002 0.00501  -0.01706 0.00705  1203 TRP A CD2 
1618 N NE1 . TRP A 197 ? 0.22751 0.16080 0.07423 0.01901  -0.01928 0.01764  1203 TRP A NE1 
1619 C CE2 . TRP A 197 ? 0.23112 0.15644 0.07096 0.00325  -0.01797 0.01684  1203 TRP A CE2 
1620 C CE3 . TRP A 197 ? 0.22607 0.16817 0.07559 -0.00649 -0.01390 0.01344  1203 TRP A CE3 
1621 C CZ2 . TRP A 197 ? 0.24638 0.16817 0.07678 0.02970  -0.02403 0.01139  1203 TRP A CZ2 
1622 C CZ3 . TRP A 197 ? 0.24361 0.17786 0.07701 -0.00027 -0.01926 0.01772  1203 TRP A CZ3 
1623 C CH2 . TRP A 197 ? 0.26224 0.16341 0.07751 0.02593  -0.02597 0.01379  1203 TRP A CH2 
1624 N N   . LEU A 198 ? 0.15277 0.13630 0.07140 0.00790  -0.01212 0.01332  1204 LEU A N   
1625 C CA  . LEU A 198 ? 0.15423 0.14951 0.07588 0.01651  -0.00741 0.01840  1204 LEU A CA  
1626 C C   . LEU A 198 ? 0.16489 0.15044 0.07681 0.02624  -0.01476 0.00601  1204 LEU A C   
1627 O O   . LEU A 198 ? 0.18112 0.15900 0.08176 0.03173  -0.01644 0.00932  1204 LEU A O   
1628 C CB  . LEU A 198 ? 0.15343 0.15521 0.07791 0.01136  -0.00873 0.01734  1204 LEU A CB  
1629 C CG  . LEU A 198 ? 0.16588 0.16764 0.07601 0.01846  -0.01255 0.00591  1204 LEU A CG  
1630 C CD1 . LEU A 198 ? 0.17586 0.16084 0.08678 0.00900  0.00261  0.01031  1204 LEU A CD1 
1631 C CD2 . LEU A 198 ? 0.18280 0.18243 0.07487 0.01888  -0.00532 0.01150  1204 LEU A CD2 
1632 N N   A PHE A 199 ? 0.15240 0.16175 0.07958 0.02882  -0.00971 0.00863  1205 PHE A N   
1633 N N   B PHE A 199 ? 0.16428 0.16709 0.07920 0.02659  -0.01735 0.00459  1205 PHE A N   
1634 C CA  A PHE A 199 ? 0.16582 0.18758 0.08460 0.03944  -0.01926 0.00605  1205 PHE A CA  
1635 C CA  B PHE A 199 ? 0.16669 0.18326 0.08143 0.03063  -0.02162 0.00244  1205 PHE A CA  
1636 C C   A PHE A 199 ? 0.16728 0.20107 0.09055 0.04619  -0.02008 0.00408  1205 PHE A C   
1637 C C   B PHE A 199 ? 0.16665 0.19371 0.08495 0.03897  -0.02198 0.00376  1205 PHE A C   
1638 O O   A PHE A 199 ? 0.17673 0.18743 0.09465 0.02637  0.00078  0.00667  1205 PHE A O   
1639 O O   B PHE A 199 ? 0.16826 0.19077 0.08559 0.03408  -0.01958 0.00342  1205 PHE A O   
1640 C CB  A PHE A 199 ? 0.16427 0.19483 0.08262 0.03169  -0.03152 0.00885  1205 PHE A CB  
1641 C CB  B PHE A 199 ? 0.16751 0.18987 0.08032 0.02447  -0.02565 -0.00234 1205 PHE A CB  
1642 C CG  A PHE A 199 ? 0.17847 0.18371 0.08127 0.03479  -0.03200 0.00015  1205 PHE A CG  
1643 C CG  B PHE A 199 ? 0.16966 0.19031 0.07900 0.02005  -0.02828 -0.00774 1205 PHE A CG  
1644 C CD1 A PHE A 199 ? 0.18845 0.17317 0.08443 -0.00190 -0.01712 0.01344  1205 PHE A CD1 
1645 C CD1 B PHE A 199 ? 0.17121 0.18928 0.07886 0.00891  -0.02935 -0.01084 1205 PHE A CD1 
1646 C CD2 A PHE A 199 ? 0.22104 0.21664 0.08445 0.05936  -0.01890 0.02021  1205 PHE A CD2 
1647 C CD2 B PHE A 199 ? 0.17867 0.19517 0.07901 0.02331  -0.02596 -0.00661 1205 PHE A CD2 
1648 C CE1 A PHE A 199 ? 0.21308 0.17792 0.08946 0.01386  -0.01922 0.02190  1205 PHE A CE1 
1649 C CE1 B PHE A 199 ? 0.18067 0.18942 0.07959 0.01219  -0.03033 -0.01099 1205 PHE A CE1 
1650 C CE2 A PHE A 199 ? 0.23083 0.21021 0.08821 0.05546  -0.02735 0.03181  1205 PHE A CE2 
1651 C CE2 B PHE A 199 ? 0.18184 0.19775 0.07913 0.02046  -0.02701 -0.00674 1205 PHE A CE2 
1652 C CZ  A PHE A 199 ? 0.23606 0.19893 0.09168 0.02904  -0.02095 0.02745  1205 PHE A CZ  
1653 C CZ  B PHE A 199 ? 0.18476 0.19547 0.07981 0.01811  -0.02719 -0.00928 1205 PHE A CZ  
1654 N N   . LEU A 200 ? 0.16818 0.20385 0.08714 0.04658  -0.02224 0.00673  1206 LEU A N   
1655 C CA  . LEU A 200 ? 0.17160 0.22444 0.09342 0.04995  -0.01054 0.01137  1206 LEU A CA  
1656 C C   . LEU A 200 ? 0.17474 0.24737 0.10448 0.08614  -0.01187 0.01565  1206 LEU A C   
1657 O O   . LEU A 200 ? 0.20011 0.23339 0.11298 0.08119  -0.00454 0.01364  1206 LEU A O   
1658 C CB  . LEU A 200 ? 0.16950 0.22376 0.09648 0.04927  -0.00474 0.01091  1206 LEU A CB  
1659 C CG  . LEU A 200 ? 0.21234 0.24261 0.09833 0.05923  0.00421  0.00344  1206 LEU A CG  
1660 C CD1 . LEU A 200 ? 0.21478 0.25045 0.09986 0.05307  0.00594  0.00597  1206 LEU A CD1 
1661 C CD2 . LEU A 200 ? 0.25108 0.26136 0.09991 0.05834  -0.00123 -0.00097 1206 LEU A CD2 
1662 N N   . GLY A 201 ? 0.16205 0.28154 0.10302 0.07419  -0.01340 0.00314  1207 GLY A N   
1663 C CA  . GLY A 201 ? 0.16427 0.32584 0.10364 0.08716  -0.01836 -0.00415 1207 GLY A CA  
1664 C C   . GLY A 201 ? 0.17389 0.33597 0.10891 0.11374  -0.01378 0.00077  1207 GLY A C   
1665 O O   . GLY A 201 ? 0.16027 0.34215 0.10774 0.08400  -0.00974 -0.00315 1207 GLY A O   
1666 N N   . VAL A 202 ? 0.18532 0.33870 0.11495 0.10637  -0.00690 0.00811  1208 VAL A N   
1667 C CA  . VAL A 202 ? 0.17722 0.36170 0.12053 0.12010  -0.01023 0.00385  1208 VAL A CA  
1668 C C   . VAL A 202 ? 0.20258 0.40493 0.12997 0.14387  -0.00763 0.00395  1208 VAL A C   
1669 O O   . VAL A 202 ? 0.24919 0.43077 0.14451 0.17684  0.00814  0.02575  1208 VAL A O   
1670 C CB  . VAL A 202 ? 0.20447 0.31366 0.12147 0.09926  -0.01625 -0.00183 1208 VAL A CB  
1671 C CG1 . VAL A 202 ? 0.20508 0.28733 0.11896 0.09353  -0.02462 -0.00305 1208 VAL A CG1 
1672 C CG2 . VAL A 202 ? 0.21381 0.31090 0.12073 0.10477  -0.00616 0.00598  1208 VAL A CG2 
1673 N N   . ALA A 203 ? 0.21040 0.42817 0.13168 0.15264  -0.01175 -0.01403 1209 ALA A N   
1674 C CA  . ALA A 203 ? 0.22334 0.45202 0.13660 0.16317  -0.00733 -0.00870 1209 ALA A CA  
1675 C C   . ALA A 203 ? 0.26144 0.43675 0.14409 0.17870  -0.01477 -0.00714 1209 ALA A C   
1676 O O   . ALA A 203 ? 0.32332 0.45846 0.15816 0.22393  -0.01421 -0.01892 1209 ALA A O   
1677 C CB  . ALA A 203 ? 0.20741 0.48122 0.13837 0.15259  -0.00120 -0.00010 1209 ALA A CB  
1678 N N   . ASN A 204 ? 0.26854 0.41043 0.13768 0.17617  -0.00385 0.01043  1210 ASN A N   
1679 C CA  . ASN A 204 ? 0.29537 0.38004 0.14111 0.17937  0.00559  0.02863  1210 ASN A CA  
1680 C C   . ASN A 204 ? 0.28109 0.34845 0.13099 0.16214  0.01482  0.03753  1210 ASN A C   
1681 O O   . ASN A 204 ? 0.26348 0.35446 0.12748 0.15510  0.01004  0.03427  1210 ASN A O   
1682 C CB  . ASN A 204 ? 0.30198 0.39168 0.14450 0.18365  0.01111  0.03404  1210 ASN A CB  
1683 C CG  . ASN A 204 ? 0.28215 0.39813 0.14516 0.18123  0.01395  0.03763  1210 ASN A CG  
1684 O OD1 . ASN A 204 ? 0.27423 0.39715 0.14731 0.17797  0.00840  0.03544  1210 ASN A OD1 
1685 N ND2 . ASN A 204 ? 0.27875 0.42846 0.15290 0.18064  0.00281  0.03285  1210 ASN A ND2 
1686 N N   . SER A 205 ? 0.30177 0.31358 0.13899 0.15761  0.01843  0.04922  1211 SER A N   
1687 C CA  . SER A 205 ? 0.32653 0.29099 0.14236 0.14005  0.01768  0.05182  1211 SER A CA  
1688 C C   . SER A 205 ? 0.30183 0.27411 0.13724 0.12606  0.01445  0.04145  1211 SER A C   
1689 O O   . SER A 205 ? 0.29717 0.28932 0.13980 0.11225  0.01215  0.04609  1211 SER A O   
1690 C CB  . SER A 205 ? 0.39888 0.30457 0.15756 0.13310  0.02401  0.06448  1211 SER A CB  
1691 O OG  . SER A 205 ? 0.46082 0.34691 0.17618 0.14686  0.02782  0.04946  1211 SER A OG  
1692 N N   . ASP A 206 ? 0.30290 0.25712 0.13002 0.12673  0.02352  0.03785  1212 ASP A N   
1693 C CA  . ASP A 206 ? 0.27348 0.25258 0.12765 0.10515  0.01939  0.02552  1212 ASP A CA  
1694 C C   . ASP A 206 ? 0.24564 0.26261 0.11416 0.10589  0.00807  0.01554  1212 ASP A C   
1695 O O   . ASP A 206 ? 0.24734 0.25147 0.10357 0.08794  -0.00464 0.01622  1212 ASP A O   
1696 C CB  . ASP A 206 ? 0.28431 0.26761 0.14687 0.12282  0.02958  0.01194  1212 ASP A CB  
1697 C CG  . ASP A 206 ? 0.31330 0.30104 0.16750 0.11937  0.03788  0.00612  1212 ASP A CG  
1698 O OD1 . ASP A 206 ? 0.35630 0.31606 0.17792 0.11193  0.04095  -0.00310 1212 ASP A OD1 
1699 O OD2 . ASP A 206 ? 0.32933 0.31286 0.17182 0.12985  0.03754  0.00358  1212 ASP A OD2 
1700 N N   . SER A 207 ? 0.21878 0.27291 0.11492 0.11535  0.00323  0.00754  1213 SER A N   
1701 C CA  . SER A 207 ? 0.17679 0.28854 0.11833 0.09462  -0.01178 0.00490  1213 SER A CA  
1702 C C   . SER A 207 ? 0.18541 0.28022 0.11601 0.09283  -0.00488 0.01019  1213 SER A C   
1703 O O   . SER A 207 ? 0.18375 0.25809 0.11412 0.08571  -0.02415 0.00686  1213 SER A O   
1704 C CB  . SER A 207 ? 0.17329 0.33923 0.12938 0.10090  -0.00956 0.00458  1213 SER A CB  
1705 O OG  . SER A 207 ? 0.18568 0.37386 0.13132 0.11358  -0.00541 -0.00265 1213 SER A OG  
1706 N N   . LEU A 208 ? 0.19402 0.26146 0.11415 0.09303  -0.00480 0.01801  1214 LEU A N   
1707 C CA  . LEU A 208 ? 0.20823 0.22442 0.11380 0.08238  0.00015  0.02543  1214 LEU A CA  
1708 C C   . LEU A 208 ? 0.18515 0.21780 0.10266 0.06747  -0.00085 0.01085  1214 LEU A C   
1709 O O   . LEU A 208 ? 0.18305 0.21478 0.10652 0.06316  0.00881  0.01635  1214 LEU A O   
1710 C CB  . LEU A 208 ? 0.22306 0.22895 0.12445 0.07211  -0.00957 0.02983  1214 LEU A CB  
1711 C CG  . LEU A 208 ? 0.25683 0.24044 0.13405 0.09139  -0.00284 0.04244  1214 LEU A CG  
1712 C CD1 . LEU A 208 ? 0.28362 0.23777 0.13616 0.08699  0.00119  0.05408  1214 LEU A CD1 
1713 C CD2 . LEU A 208 ? 0.25837 0.25328 0.13763 0.09364  0.00234  0.04474  1214 LEU A CD2 
1714 N N   . LEU A 209 ? 0.16604 0.21842 0.09666 0.06256  0.00045  0.01745  1215 LEU A N   
1715 C CA  . LEU A 209 ? 0.15424 0.20069 0.09467 0.05512  -0.00251 0.01787  1215 LEU A CA  
1716 C C   . LEU A 209 ? 0.14665 0.19799 0.08854 0.02717  0.00158  0.00601  1215 LEU A C   
1717 O O   . LEU A 209 ? 0.16170 0.19234 0.08452 0.02426  0.00491  0.00796  1215 LEU A O   
1718 C CB  . LEU A 209 ? 0.15035 0.18895 0.09525 0.03366  -0.00783 0.00734  1215 LEU A CB  
1719 C CG  . LEU A 209 ? 0.15063 0.21389 0.09639 0.03697  0.00052  0.01878  1215 LEU A CG  
1720 C CD1 . LEU A 209 ? 0.15446 0.21968 0.10335 0.02023  -0.00317 0.00699  1215 LEU A CD1 
1721 C CD2 . LEU A 209 ? 0.15923 0.23749 0.09949 0.03023  -0.00304 0.02206  1215 LEU A CD2 
1722 N N   . TYR A 210 ? 0.15223 0.19084 0.08892 0.03581  -0.00643 0.00567  1216 TYR A N   
1723 C CA  . TYR A 210 ? 0.16464 0.16566 0.09011 0.01656  0.00079  0.00418  1216 TYR A CA  
1724 C C   . TYR A 210 ? 0.17253 0.16813 0.08385 0.02495  0.00077  0.01708  1216 TYR A C   
1725 O O   . TYR A 210 ? 0.18012 0.15852 0.08560 0.00807  -0.00043 0.00818  1216 TYR A O   
1726 C CB  . TYR A 210 ? 0.15003 0.17077 0.09560 0.02664  0.00694  0.01062  1216 TYR A CB  
1727 C CG  . TYR A 210 ? 0.13963 0.16067 0.09213 0.02273  -0.00360 0.01292  1216 TYR A CG  
1728 C CD1 . TYR A 210 ? 0.14227 0.16135 0.08774 0.00951  -0.00417 0.00482  1216 TYR A CD1 
1729 C CD2 . TYR A 210 ? 0.12305 0.16245 0.09285 0.01528  -0.00063 0.01200  1216 TYR A CD2 
1730 C CE1 . TYR A 210 ? 0.11905 0.16774 0.08835 0.01485  0.00353  0.01488  1216 TYR A CE1 
1731 C CE2 . TYR A 210 ? 0.11982 0.18168 0.09284 0.01674  -0.00038 0.02284  1216 TYR A CE2 
1732 C CZ  . TYR A 210 ? 0.11469 0.17440 0.09259 0.01518  -0.00014 0.01921  1216 TYR A CZ  
1733 O OH  . TYR A 210 ? 0.12283 0.18100 0.09335 0.01377  0.00006  0.01079  1216 TYR A OH  
1734 N N   . ASP A 211 ? 0.18562 0.16211 0.09288 0.02496  -0.00742 0.01303  1217 ASP A N   
1735 C CA  . ASP A 211 ? 0.21185 0.14626 0.09828 0.03419  -0.00423 0.01779  1217 ASP A CA  
1736 C C   . ASP A 211 ? 0.21667 0.14573 0.10282 0.02544  -0.00885 0.00983  1217 ASP A C   
1737 O O   . ASP A 211 ? 0.22176 0.18187 0.10849 0.02248  -0.00111 0.02581  1217 ASP A O   
1738 C CB  . ASP A 211 ? 0.24368 0.16785 0.09889 0.04092  0.00220  0.02830  1217 ASP A CB  
1739 C CG  . ASP A 211 ? 0.28126 0.17865 0.10280 0.07623  0.01265  0.01409  1217 ASP A CG  
1740 O OD1 . ASP A 211 ? 0.27802 0.19667 0.09475 0.07541  0.00649  0.02468  1217 ASP A OD1 
1741 O OD2 . ASP A 211 ? 0.34654 0.18995 0.11342 0.07464  0.02034  0.01567  1217 ASP A OD2 
1742 N N   . GLU A 212 ? 0.20841 0.16090 0.11566 0.03981  -0.01597 -0.00156 1218 GLU A N   
1743 C CA  . GLU A 212 ? 0.21787 0.16418 0.14024 0.03084  -0.02029 -0.01247 1218 GLU A CA  
1744 C C   . GLU A 212 ? 0.22454 0.15525 0.11448 0.01061  -0.01331 0.00093  1218 GLU A C   
1745 O O   . GLU A 212 ? 0.22960 0.16122 0.10878 -0.00728 -0.00229 0.00175  1218 GLU A O   
1751 N N   . GLU A 213 ? 0.20530 0.15689 0.09767 0.02014  -0.01273 0.00545  1219 GLU A N   
1752 C CA  . GLU A 213 ? 0.19405 0.15747 0.09376 0.00973  -0.00296 0.01234  1219 GLU A CA  
1753 C C   . GLU A 213 ? 0.20386 0.15704 0.08648 0.01174  -0.00333 0.01765  1219 GLU A C   
1754 O O   . GLU A 213 ? 0.21916 0.15847 0.08631 0.00724  -0.00662 0.00979  1219 GLU A O   
1755 C CB  . GLU A 213 ? 0.18658 0.15359 0.10191 0.01234  -0.00560 0.02093  1219 GLU A CB  
1756 C CG  . GLU A 213 ? 0.17957 0.15412 0.10115 0.01759  -0.00273 0.01517  1219 GLU A CG  
1757 C CD  . GLU A 213 ? 0.16337 0.15779 0.08928 -0.00111 -0.01299 0.00593  1219 GLU A CD  
1758 O OE1 . GLU A 213 ? 0.18768 0.16638 0.08463 0.01137  -0.01275 0.00871  1219 GLU A OE1 
1759 O OE2 . GLU A 213 ? 0.15587 0.16374 0.08462 0.00732  -0.01347 0.01130  1219 GLU A OE2 
1760 N N   . PHE A 214 ? 0.20961 0.16760 0.08469 0.02153  -0.01927 -0.00077 1220 PHE A N   
1761 C CA  . PHE A 214 ? 0.20522 0.18741 0.08769 0.01852  -0.01512 0.00192  1220 PHE A CA  
1762 C C   . PHE A 214 ? 0.21767 0.19330 0.09436 0.02748  -0.01006 0.00099  1220 PHE A C   
1763 O O   . PHE A 214 ? 0.23335 0.22235 0.09311 0.02851  -0.00316 -0.00065 1220 PHE A O   
1764 C CB  . PHE A 214 ? 0.21181 0.17603 0.08475 0.03422  -0.02126 -0.00025 1220 PHE A CB  
1765 C CG  . PHE A 214 ? 0.19867 0.17398 0.08072 0.03704  -0.02493 -0.00697 1220 PHE A CG  
1766 C CD1 . PHE A 214 ? 0.21355 0.18234 0.08702 0.02622  -0.02862 -0.00161 1220 PHE A CD1 
1767 C CD2 . PHE A 214 ? 0.21307 0.18629 0.08208 0.04946  -0.01448 -0.00933 1220 PHE A CD2 
1768 C CE1 . PHE A 214 ? 0.19110 0.19262 0.08520 0.02716  -0.02512 0.00283  1220 PHE A CE1 
1769 C CE2 . PHE A 214 ? 0.21119 0.19885 0.08389 0.04584  -0.00612 0.00154  1220 PHE A CE2 
1770 C CZ  . PHE A 214 ? 0.19208 0.19168 0.08005 0.03043  -0.01003 0.00218  1220 PHE A CZ  
1771 N N   . THR A 215 ? 0.25596 0.17829 0.10508 0.04467  -0.00302 0.02360  1221 THR A N   
1772 C CA  . THR A 215 ? 0.27404 0.17621 0.12692 0.02928  -0.00275 0.02834  1221 THR A CA  
1773 C C   . THR A 215 ? 0.26626 0.16588 0.12961 0.01904  0.01258  0.02555  1221 THR A C   
1774 O O   . THR A 215 ? 0.28966 0.20165 0.13183 0.00713  0.02772  0.03722  1221 THR A O   
1775 C CB  . THR A 215 ? 0.30920 0.18069 0.15305 0.04241  -0.01748 0.02714  1221 THR A CB  
1776 O OG1 . THR A 215 ? 0.32998 0.21945 0.17140 0.06156  -0.02186 0.01421  1221 THR A OG1 
1777 C CG2 . THR A 215 ? 0.34637 0.21487 0.16681 0.05119  -0.00886 0.01732  1221 THR A CG2 
1778 N N   . SER A 216 ? 0.23915 0.17090 0.14432 0.01180  0.01415  0.01458  1222 SER A N   
1779 C CA  A SER A 216 ? 0.23145 0.18924 0.16715 0.00495  0.01012  0.01074  1222 SER A CA  
1780 C CA  B SER A 216 ? 0.21147 0.16762 0.14842 0.00186  0.01019  0.01067  1222 SER A CA  
1781 C CA  C SER A 216 ? 0.21388 0.16956 0.15017 0.00234  0.01022  0.01035  1222 SER A CA  
1782 C C   . SER A 216 ? 0.21735 0.17444 0.13235 -0.00278 0.00559  0.00783  1222 SER A C   
1783 O O   . SER A 216 ? 0.22798 0.19112 0.10776 -0.03493 0.00009  0.00469  1222 SER A O   
1790 N N   . TYR A 217 ? 0.21994 0.15215 0.10987 -0.01703 0.00594  0.00812  1223 TYR A N   
1791 C CA  . TYR A 217 ? 0.20875 0.14310 0.10255 -0.01806 0.00633  0.01662  1223 TYR A CA  
1792 C C   . TYR A 217 ? 0.22143 0.14615 0.10082 -0.01881 0.00179  0.01624  1223 TYR A C   
1793 O O   . TYR A 217 ? 0.21946 0.15693 0.10410 -0.03597 0.00357  0.01598  1223 TYR A O   
1794 C CB  . TYR A 217 ? 0.19275 0.14061 0.09720 -0.01842 0.00935  0.01586  1223 TYR A CB  
1795 C CG  . TYR A 217 ? 0.18089 0.13710 0.09412 -0.00964 0.00638  0.01540  1223 TYR A CG  
1796 C CD1 . TYR A 217 ? 0.17712 0.14553 0.10374 -0.01059 -0.00305 0.01917  1223 TYR A CD1 
1797 C CD2 . TYR A 217 ? 0.17224 0.14641 0.08962 -0.00989 0.00083  0.01336  1223 TYR A CD2 
1798 C CE1 . TYR A 217 ? 0.16395 0.16040 0.10202 -0.01196 -0.01014 0.01759  1223 TYR A CE1 
1799 C CE2 . TYR A 217 ? 0.15767 0.15753 0.08288 -0.00357 -0.00585 0.01585  1223 TYR A CE2 
1800 C CZ  . TYR A 217 ? 0.14613 0.14273 0.08911 -0.00587 -0.00811 0.01585  1223 TYR A CZ  
1801 O OH  . TYR A 217 ? 0.16323 0.15043 0.09426 -0.01862 -0.00583 0.02740  1223 TYR A OH  
1802 N N   . LEU A 218 ? 0.23761 0.14637 0.10270 -0.01802 -0.00638 0.01970  1224 LEU A N   
1803 C CA  . LEU A 218 ? 0.26072 0.14148 0.10009 -0.01483 -0.00700 0.02353  1224 LEU A CA  
1804 C C   . LEU A 218 ? 0.29129 0.13938 0.09409 -0.02016 -0.01804 0.01684  1224 LEU A C   
1805 O O   . LEU A 218 ? 0.30334 0.15416 0.09003 -0.03666 -0.01740 0.01980  1224 LEU A O   
1806 C CB  . LEU A 218 ? 0.27400 0.16808 0.10081 0.00871  -0.01733 0.01247  1224 LEU A CB  
1807 C CG  . LEU A 218 ? 0.27132 0.17071 0.10241 0.00044  -0.01511 0.00461  1224 LEU A CG  
1808 C CD1 . LEU A 218 ? 0.27612 0.18155 0.11127 0.00911  -0.01114 0.01615  1224 LEU A CD1 
1809 C CD2 . LEU A 218 ? 0.26125 0.18992 0.09101 -0.02227 -0.01740 -0.00672 1224 LEU A CD2 
1810 N N   . LYS A 219 ? 0.30960 0.14084 0.09694 -0.02174 -0.02797 0.00799  1225 LYS A N   
1811 C CA  . LYS A 219 ? 0.33956 0.15491 0.11359 -0.03113 -0.02520 -0.00445 1225 LYS A CA  
1812 C C   . LYS A 219 ? 0.33426 0.17321 0.11187 -0.06344 -0.01756 0.00558  1225 LYS A C   
1813 O O   . LYS A 219 ? 0.33770 0.21892 0.12672 -0.08785 -0.01318 0.00660  1225 LYS A O   
1814 C CB  . LYS A 219 ? 0.37332 0.22915 0.13423 0.00831  -0.02994 -0.03993 1225 LYS A CB  
1815 C CG  . LYS A 219 ? 0.43398 0.33615 0.15171 0.06421  -0.01786 -0.03761 1225 LYS A CG  
1816 C CD  . LYS A 219 ? 0.49016 0.42962 0.16488 0.11031  -0.00314 -0.00759 1225 LYS A CD  
1817 C CE  . LYS A 219 ? 0.53279 0.50390 0.17423 0.13901  0.00836  0.00952  1225 LYS A CE  
1818 N NZ  . LYS A 219 ? 0.55850 0.53523 0.17938 0.15212  0.01393  0.01959  1225 LYS A NZ  
1819 N N   . GLN A 220 ? 0.31446 0.15748 0.09840 -0.04514 -0.03246 -0.00519 1226 GLN A N   
1820 C CA  . GLN A 220 ? 0.31394 0.20509 0.10571 -0.04231 -0.03483 0.00741  1226 GLN A CA  
1821 C C   . GLN A 220 ? 0.26336 0.19067 0.10577 -0.05828 -0.03601 0.01051  1226 GLN A C   
1822 O O   . GLN A 220 ? 0.24680 0.24049 0.11407 -0.06003 -0.03679 -0.01243 1226 GLN A O   
1823 C CB  . GLN A 220 ? 0.38480 0.25079 0.11239 -0.01411 -0.02250 0.02046  1226 GLN A CB  
1824 C CG  . GLN A 220 ? 0.49022 0.32883 0.13025 0.02910  -0.00492 0.02966  1226 GLN A CG  
1825 C CD  . GLN A 220 ? 0.58938 0.40673 0.16057 0.08754  0.01060  0.03095  1226 GLN A CD  
1826 O OE1 . GLN A 220 ? 0.63550 0.44437 0.17224 0.09725  0.01265  0.02648  1226 GLN A OE1 
1827 N NE2 . GLN A 220 ? 0.60852 0.44654 0.16866 0.09676  0.01559  0.03529  1226 GLN A NE2 
1828 N N   . TYR A 221 ? 0.26204 0.15881 0.08898 -0.05089 -0.03858 0.01208  1227 TYR A N   
1829 C CA  . TYR A 221 ? 0.25284 0.15062 0.09252 -0.05453 -0.02646 0.01479  1227 TYR A CA  
1830 C C   . TYR A 221 ? 0.22971 0.14753 0.08906 -0.05975 -0.02712 0.01587  1227 TYR A C   
1831 O O   . TYR A 221 ? 0.21132 0.15492 0.08897 -0.04378 -0.02709 0.01955  1227 TYR A O   
1832 C CB  . TYR A 221 ? 0.26971 0.15034 0.10594 -0.04940 -0.03965 0.02848  1227 TYR A CB  
1833 C CG  . TYR A 221 ? 0.26865 0.16941 0.13498 -0.05690 -0.04890 0.03731  1227 TYR A CG  
1834 C CD1 . TYR A 221 ? 0.28888 0.19741 0.16275 -0.04804 -0.04199 0.03227  1227 TYR A CD1 
1835 C CD2 . TYR A 221 ? 0.28540 0.18742 0.14057 -0.05933 -0.06232 0.04986  1227 TYR A CD2 
1836 C CE1 . TYR A 221 ? 0.30492 0.23820 0.17767 -0.04571 -0.05227 0.03323  1227 TYR A CE1 
1837 C CE2 . TYR A 221 ? 0.30267 0.20493 0.16095 -0.06219 -0.06609 0.05601  1227 TYR A CE2 
1838 C CZ  . TYR A 221 ? 0.31612 0.24640 0.18018 -0.02253 -0.06937 0.04253  1227 TYR A CZ  
1839 O OH  . TYR A 221 ? 0.33043 0.29063 0.19636 -0.01687 -0.07305 0.05212  1227 TYR A OH  
1840 N N   . PRO A 222 ? 0.24861 0.13876 0.09331 -0.04692 -0.03390 0.01295  1228 PRO A N   
1841 C CA  . PRO A 222 ? 0.25628 0.13700 0.09494 -0.04407 -0.03646 0.02136  1228 PRO A CA  
1842 C C   . PRO A 222 ? 0.23719 0.16319 0.09596 -0.05188 -0.02946 0.02672  1228 PRO A C   
1843 O O   . PRO A 222 ? 0.24916 0.18538 0.10044 -0.03562 -0.03693 0.02387  1228 PRO A O   
1844 C CB  . PRO A 222 ? 0.27072 0.15128 0.10107 -0.05128 -0.03707 0.01506  1228 PRO A CB  
1845 C CG  . PRO A 222 ? 0.26207 0.16455 0.10908 -0.05677 -0.03764 0.02055  1228 PRO A CG  
1846 C CD  . PRO A 222 ? 0.26501 0.14256 0.11001 -0.05590 -0.03329 0.00862  1228 PRO A CD  
1847 N N   . ASP A 223 ? 0.21442 0.14919 0.09571 -0.05519 -0.01649 0.01977  1229 ASP A N   
1848 C CA  A ASP A 223 ? 0.21966 0.17362 0.09814 -0.06807 -0.00536 0.03101  1229 ASP A CA  
1849 C CA  B ASP A 223 ? 0.23173 0.17920 0.09822 -0.05144 -0.01113 0.01871  1229 ASP A CA  
1850 C C   . ASP A 223 ? 0.22291 0.17074 0.09265 -0.05435 -0.00728 0.02204  1229 ASP A C   
1851 O O   . ASP A 223 ? 0.28493 0.18123 0.10071 -0.02573 0.01776  0.01865  1229 ASP A O   
1852 C CB  A ASP A 223 ? 0.23239 0.21565 0.11335 -0.10182 0.00812  0.03874  1229 ASP A CB  
1853 C CB  B ASP A 223 ? 0.27335 0.24444 0.10714 -0.04787 -0.00566 0.00724  1229 ASP A CB  
1854 C CG  A ASP A 223 ? 0.26763 0.30573 0.12341 -0.07127 0.02158  0.06405  1229 ASP A CG  
1855 C CG  B ASP A 223 ? 0.31246 0.32930 0.11645 -0.02788 -0.00407 0.00058  1229 ASP A CG  
1856 O OD1 A ASP A 223 ? 0.26630 0.33571 0.12636 -0.08535 0.01257  0.06248  1229 ASP A OD1 
1857 O OD1 B ASP A 223 ? 0.32511 0.34646 0.12263 -0.02513 -0.00599 0.00732  1229 ASP A OD1 
1858 O OD2 A ASP A 223 ? 0.31623 0.35369 0.12789 -0.01788 0.04026  0.07055  1229 ASP A OD2 
1859 O OD2 B ASP A 223 ? 0.33583 0.37955 0.12228 0.00672  0.00297  -0.01854 1229 ASP A OD2 
1860 N N   . ASN A 224 ? 0.20080 0.15188 0.09073 -0.04504 -0.01294 0.01219  1230 ASN A N   
1861 C CA  . ASN A 224 ? 0.18864 0.14860 0.09383 -0.03171 -0.00896 0.01227  1230 ASN A CA  
1862 C C   . ASN A 224 ? 0.17883 0.14766 0.08203 -0.03406 -0.02083 0.01424  1230 ASN A C   
1863 O O   . ASN A 224 ? 0.18566 0.14135 0.08226 -0.02300 -0.01948 0.00462  1230 ASN A O   
1864 C CB  . ASN A 224 ? 0.18661 0.17342 0.10744 -0.02943 -0.01695 0.01654  1230 ASN A CB  
1865 C CG  . ASN A 224 ? 0.19931 0.16549 0.12419 -0.03812 -0.03529 0.00529  1230 ASN A CG  
1866 O OD1 . ASN A 224 ? 0.22058 0.18026 0.14702 -0.03920 -0.04220 -0.01190 1230 ASN A OD1 
1867 N ND2 . ASN A 224 ? 0.17992 0.17237 0.12922 -0.03400 -0.02697 0.01446  1230 ASN A ND2 
1868 N N   . PHE A 225 ? 0.19600 0.14305 0.08727 -0.02784 -0.01932 0.00479  1231 PHE A N   
1869 C CA  . PHE A 225 ? 0.19395 0.14153 0.09382 -0.02624 -0.01736 0.00694  1231 PHE A CA  
1870 C C   . PHE A 225 ? 0.20346 0.12986 0.10274 -0.01576 -0.01396 0.00442  1231 PHE A C   
1871 O O   . PHE A 225 ? 0.23592 0.14050 0.13092 -0.02594 -0.01225 0.00391  1231 PHE A O   
1872 C CB  . PHE A 225 ? 0.20312 0.14433 0.08494 -0.02494 -0.01144 0.00026  1231 PHE A CB  
1873 C CG  . PHE A 225 ? 0.18649 0.14234 0.07727 -0.01771 -0.00528 0.00957  1231 PHE A CG  
1874 C CD1 . PHE A 225 ? 0.18225 0.14919 0.08466 -0.01185 -0.01014 0.01395  1231 PHE A CD1 
1875 C CD2 . PHE A 225 ? 0.20993 0.15594 0.07718 -0.00134 -0.01499 -0.00019 1231 PHE A CD2 
1876 C CE1 . PHE A 225 ? 0.18761 0.16226 0.08915 0.00981  -0.01371 0.01788  1231 PHE A CE1 
1877 C CE2 . PHE A 225 ? 0.21368 0.18862 0.07841 0.02008  -0.01003 0.00754  1231 PHE A CE2 
1878 C CZ  . PHE A 225 ? 0.19482 0.16812 0.08570 -0.00377 -0.01123 0.02028  1231 PHE A CZ  
1879 N N   . ARG A 226 ? 0.19961 0.13062 0.08084 -0.00414 -0.01171 0.00197  1232 ARG A N   
1880 C CA  . ARG A 226 ? 0.21455 0.14196 0.07648 -0.00197 -0.00670 0.01332  1232 ARG A CA  
1881 C C   . ARG A 226 ? 0.20368 0.14692 0.07335 -0.00007 -0.00758 0.01801  1232 ARG A C   
1882 O O   . ARG A 226 ? 0.19216 0.14441 0.07520 -0.00570 -0.01368 0.01111  1232 ARG A O   
1883 C CB  . ARG A 226 ? 0.23579 0.15549 0.07974 -0.00355 0.00326  0.02206  1232 ARG A CB  
1884 C CG  . ARG A 226 ? 0.26475 0.16095 0.08948 -0.00493 0.00963  0.02273  1232 ARG A CG  
1885 C CD  . ARG A 226 ? 0.29339 0.17859 0.09834 0.00975  0.00801  0.02637  1232 ARG A CD  
1886 N NE  . ARG A 226 ? 0.30791 0.16997 0.09511 -0.00731 -0.00650 0.02583  1232 ARG A NE  
1887 C CZ  . ARG A 226 ? 0.33106 0.19091 0.09801 -0.00038 -0.01573 0.01748  1232 ARG A CZ  
1888 N NH1 . ARG A 226 ? 0.34567 0.22474 0.09397 -0.00172 0.00754  0.02062  1232 ARG A NH1 
1889 N NH2 . ARG A 226 ? 0.34225 0.19932 0.10575 0.00334  -0.03691 0.02441  1232 ARG A NH2 
1890 N N   . TYR A 227 ? 0.22913 0.14092 0.07878 0.01050  -0.00540 0.01458  1233 TYR A N   
1891 C CA  . TYR A 227 ? 0.22689 0.15588 0.08197 0.02715  0.00049  0.02055  1233 TYR A CA  
1892 C C   . TYR A 227 ? 0.26055 0.14136 0.08678 0.03590  -0.00414 0.01832  1233 TYR A C   
1893 O O   . TYR A 227 ? 0.29211 0.15426 0.09890 0.04532  -0.00438 0.01024  1233 TYR A O   
1894 C CB  . TYR A 227 ? 0.23350 0.15523 0.07907 0.01717  0.00171  0.01491  1233 TYR A CB  
1895 C CG  . TYR A 227 ? 0.23782 0.14648 0.08032 0.03633  -0.00732 0.02178  1233 TYR A CG  
1896 C CD1 . TYR A 227 ? 0.23089 0.16164 0.08159 0.03439  -0.00417 0.01311  1233 TYR A CD1 
1897 C CD2 . TYR A 227 ? 0.23882 0.16336 0.08357 0.03761  -0.00983 0.00868  1233 TYR A CD2 
1898 C CE1 . TYR A 227 ? 0.23335 0.17911 0.08512 0.05665  -0.00406 0.01243  1233 TYR A CE1 
1899 C CE2 . TYR A 227 ? 0.23916 0.18431 0.08487 0.04351  -0.00577 0.01748  1233 TYR A CE2 
1900 C CZ  . TYR A 227 ? 0.21762 0.17754 0.08493 0.04356  -0.00712 0.02175  1233 TYR A CZ  
1901 O OH  . TYR A 227 ? 0.21387 0.21060 0.08520 0.04452  0.00510  0.02464  1233 TYR A OH  
1902 N N   . ASP A 228 ? 0.25564 0.16628 0.08639 0.05184  -0.00611 0.01517  1234 ASP A N   
1903 C CA  . ASP A 228 ? 0.26705 0.16967 0.09487 0.07210  -0.01845 0.00976  1234 ASP A CA  
1904 C C   . ASP A 228 ? 0.25608 0.19814 0.10745 0.08103  -0.01066 0.01943  1234 ASP A C   
1905 O O   . ASP A 228 ? 0.22567 0.20202 0.11419 0.06821  0.00066  0.00601  1234 ASP A O   
1906 C CB  . ASP A 228 ? 0.29230 0.18704 0.09585 0.07278  -0.02066 0.01794  1234 ASP A CB  
1907 C CG  . ASP A 228 ? 0.28762 0.16031 0.09926 0.06205  -0.01723 0.02118  1234 ASP A CG  
1908 O OD1 . ASP A 228 ? 0.29957 0.16938 0.10754 0.06024  -0.02072 0.02038  1234 ASP A OD1 
1909 O OD2 . ASP A 228 ? 0.27770 0.15819 0.09991 0.04562  -0.01535 0.02409  1234 ASP A OD2 
1910 N N   . LYS A 229 ? 0.27831 0.21063 0.11061 0.10963  -0.00307 0.02338  1235 LYS A N   
1911 C CA  . LYS A 229 ? 0.28983 0.24206 0.12139 0.12130  -0.01704 0.01550  1235 LYS A CA  
1912 C C   . LYS A 229 ? 0.30292 0.25986 0.16112 0.14236  -0.03629 0.01215  1235 LYS A C   
1913 O O   . LYS A 229 ? 0.34007 0.23851 0.15287 0.13590  -0.03854 0.02002  1235 LYS A O   
1914 C CB  . LYS A 229 ? 0.29674 0.24927 0.11040 0.11274  -0.01985 0.01992  1235 LYS A CB  
1915 C CG  . LYS A 229 ? 0.29762 0.22692 0.10711 0.10021  -0.01054 0.02622  1235 LYS A CG  
1916 C CD  . LYS A 229 ? 0.30640 0.22938 0.10768 0.07581  -0.00918 0.04274  1235 LYS A CD  
1917 C CE  . LYS A 229 ? 0.32552 0.22054 0.10797 0.05986  -0.00296 0.04647  1235 LYS A CE  
1918 N NZ  . LYS A 229 ? 0.35506 0.24616 0.10986 0.07716  -0.01294 0.03143  1235 LYS A NZ  
1919 N N   A ALA A 230 ? 0.25943 0.25171 0.15520 0.14485  -0.02812 0.00475  1236 ALA A N   
1920 N N   B ALA A 230 ? 0.32557 0.30414 0.23833 0.12729  -0.05431 0.00605  1236 ALA A N   
1921 C CA  A ALA A 230 ? 0.22387 0.26125 0.16238 0.13925  -0.02203 0.00447  1236 ALA A CA  
1922 C CA  B ALA A 230 ? 0.35070 0.35589 0.32164 0.10743  -0.07271 -0.00254 1236 ALA A CA  
1923 C C   A ALA A 230 ? 0.21448 0.25878 0.13591 0.13955  -0.00208 0.00449  1236 ALA A C   
1924 C C   B ALA A 230 ? 0.31490 0.32754 0.30882 0.08719  -0.08950 -0.00867 1236 ALA A C   
1925 O O   A ALA A 230 ? 0.18878 0.26125 0.13001 0.12942  0.00062  -0.00572 1236 ALA A O   
1926 O O   B ALA A 230 ? 0.30167 0.31632 0.30916 0.06427  -0.09077 -0.01421 1236 ALA A O   
1929 N N   A LEU A 231 ? 0.23243 0.25324 0.12465 0.14233  0.00553  0.01922  1237 LEU A N   
1930 N N   B LEU A 231 ? 0.28170 0.29234 0.29670 0.07537  -0.10555 -0.00956 1237 LEU A N   
1931 C CA  A LEU A 231 ? 0.25375 0.25093 0.12349 0.14641  0.00991  0.02470  1237 LEU A CA  
1932 C CA  B LEU A 231 ? 0.27485 0.28873 0.28642 0.08944  -0.10444 -0.00548 1237 LEU A CA  
1933 C C   A LEU A 231 ? 0.23494 0.28190 0.12283 0.13880  -0.00003 0.02900  1237 LEU A C   
1934 C C   B LEU A 231 ? 0.26605 0.29316 0.28036 0.08964  -0.09515 -0.00048 1237 LEU A C   
1935 O O   A LEU A 231 ? 0.23956 0.29892 0.12950 0.14381  0.00219  0.03368  1237 LEU A O   
1936 O O   B LEU A 231 ? 0.24240 0.27547 0.27697 0.09045  -0.10167 -0.00286 1237 LEU A O   
1937 C CB  A LEU A 231 ? 0.29693 0.22791 0.12602 0.14532  0.01648  0.02238  1237 LEU A CB  
1938 C CB  B LEU A 231 ? 0.28480 0.29666 0.28327 0.09392  -0.11237 -0.00522 1237 LEU A CB  
1939 C CG  A LEU A 231 ? 0.31068 0.20870 0.12554 0.11022  0.02324  0.01179  1237 LEU A CG  
1940 C CG  B LEU A 231 ? 0.30286 0.30968 0.28228 0.10679  -0.11506 -0.00201 1237 LEU A CG  
1941 C CD1 A LEU A 231 ? 0.30426 0.20811 0.12819 0.10556  0.02482  0.01179  1237 LEU A CD1 
1942 C CD1 B LEU A 231 ? 0.31332 0.31539 0.28139 0.10297  -0.11718 -0.00552 1237 LEU A CD1 
1943 C CD2 A LEU A 231 ? 0.32169 0.20921 0.12553 0.08755  0.01286  0.01467  1237 LEU A CD2 
1944 C CD2 B LEU A 231 ? 0.31329 0.30972 0.28128 0.11212  -0.11763 0.00109  1237 LEU A CD2 
1945 N N   A SER A 232 ? 0.23457 0.29899 0.12992 0.14232  -0.01196 0.01909  1238 SER A N   
1946 N N   B SER A 232 ? 0.29075 0.32343 0.27909 0.10213  -0.08168 0.00993  1238 SER A N   
1947 C CA  A SER A 232 ? 0.22998 0.31533 0.13713 0.13482  -0.02846 0.00694  1238 SER A CA  
1948 C CA  B SER A 232 ? 0.30784 0.36830 0.27998 0.12816  -0.07176 0.02228  1238 SER A CA  
1949 C C   A SER A 232 ? 0.22881 0.30765 0.13825 0.12802  -0.03208 0.01581  1238 SER A C   
1950 C C   B SER A 232 ? 0.28727 0.35689 0.27843 0.11869  -0.06775 0.04255  1238 SER A C   
1951 O O   A SER A 232 ? 0.24647 0.33985 0.13884 0.12894  -0.03547 0.01634  1238 SER A O   
1952 O O   B SER A 232 ? 0.29179 0.35196 0.27903 0.12729  -0.07059 0.05282  1238 SER A O   
1953 C CB  A SER A 232 ? 0.23122 0.35216 0.14641 0.11056  -0.02508 0.00202  1238 SER A CB  
1954 C CB  B SER A 232 ? 0.33278 0.42094 0.28242 0.14847  -0.07035 0.01215  1238 SER A CB  
1955 O OG  A SER A 232 ? 0.24740 0.38588 0.15046 0.09797  -0.02931 -0.01618 1238 SER A OG  
1956 O OG  B SER A 232 ? 0.36875 0.46959 0.28487 0.14617  -0.06446 0.00560  1238 SER A OG  
1957 N N   A ARG A 233 ? 0.22067 0.29091 0.14153 0.11085  -0.01808 0.01991  1239 ARG A N   
1958 N N   B ARG A 233 ? 0.29043 0.35179 0.27758 0.12002  -0.05278 0.04949  1239 ARG A N   
1959 C CA  A ARG A 233 ? 0.22103 0.28852 0.15145 0.11379  -0.01653 0.02421  1239 ARG A CA  
1960 C CA  B ARG A 233 ? 0.30854 0.36506 0.27805 0.11907  -0.04035 0.05364  1239 ARG A CA  
1961 C C   A ARG A 233 ? 0.25911 0.28398 0.14477 0.13030  -0.01251 0.02647  1239 ARG A C   
1962 C C   B ARG A 233 ? 0.31734 0.32934 0.26350 0.10485  -0.02690 0.05888  1239 ARG A C   
1963 O O   A ARG A 233 ? 0.29171 0.28799 0.14478 0.14075  -0.00097 0.02236  1239 ARG A O   
1964 O O   B ARG A 233 ? 0.31935 0.31747 0.26226 0.11371  -0.01878 0.06002  1239 ARG A O   
1965 C CB  A ARG A 233 ? 0.19567 0.30136 0.16928 0.09825  -0.01671 0.02824  1239 ARG A CB  
1966 C CB  B ARG A 233 ? 0.32157 0.39590 0.29234 0.11938  -0.04047 0.05656  1239 ARG A CB  
1967 C CG  A ARG A 233 ? 0.20064 0.33811 0.18752 0.09031  -0.02465 0.03427  1239 ARG A CG  
1968 C CG  B ARG A 233 ? 0.34619 0.42951 0.30695 0.11847  -0.04357 0.05768  1239 ARG A CG  
1969 C CD  A ARG A 233 ? 0.21341 0.37769 0.20080 0.07621  -0.04617 0.03725  1239 ARG A CD  
1970 C CD  B ARG A 233 ? 0.37916 0.45793 0.32062 0.11861  -0.04668 0.05943  1239 ARG A CD  
1971 N NE  A ARG A 233 ? 0.25070 0.43142 0.21298 0.07160  -0.05072 0.03758  1239 ARG A NE  
1972 N NE  B ARG A 233 ? 0.39993 0.48366 0.33207 0.10918  -0.05190 0.05801  1239 ARG A NE  
1973 C CZ  A ARG A 233 ? 0.26837 0.46295 0.21916 0.07449  -0.04970 0.03902  1239 ARG A CZ  
1974 C CZ  B ARG A 233 ? 0.40443 0.50518 0.34059 0.10068  -0.05949 0.05699  1239 ARG A CZ  
1975 N NH1 A ARG A 233 ? 0.27102 0.46730 0.22036 0.07997  -0.04485 0.03636  1239 ARG A NH1 
1976 N NH1 B ARG A 233 ? 0.41415 0.52048 0.34350 0.10164  -0.05747 0.05607  1239 ARG A NH1 
1977 N NH2 A ARG A 233 ? 0.28804 0.47021 0.22324 0.07635  -0.05056 0.04041  1239 ARG A NH2 
1978 N NH2 B ARG A 233 ? 0.40509 0.50503 0.34336 0.09632  -0.06300 0.05906  1239 ARG A NH2 
1979 N N   A GLU A 234 ? 0.27178 0.27106 0.13945 0.12046  -0.00700 0.04155  1240 GLU A N   
1980 N N   B GLU A 234 ? 0.32013 0.29443 0.25156 0.09533  -0.02346 0.05688  1240 GLU A N   
1981 C CA  A GLU A 234 ? 0.28375 0.25437 0.13933 0.11162  -0.00176 0.04219  1240 GLU A CA  
1982 C CA  B GLU A 234 ? 0.33614 0.27659 0.24250 0.06728  -0.01860 0.04201  1240 GLU A CA  
1983 C C   A GLU A 234 ? 0.24359 0.22669 0.14637 0.07098  -0.00247 0.03337  1240 GLU A C   
1984 C C   B GLU A 234 ? 0.30249 0.23181 0.22891 0.05561  -0.02947 0.02923  1240 GLU A C   
1985 O O   A GLU A 234 ? 0.26048 0.24989 0.14636 0.07076  -0.00820 0.01868  1240 GLU A O   
1986 O O   B GLU A 234 ? 0.32886 0.25356 0.23151 0.06609  -0.01981 0.02219  1240 GLU A O   
1987 C CB  A GLU A 234 ? 0.32211 0.28658 0.13985 0.14386  0.00554  0.03942  1240 GLU A CB  
1988 C CB  B GLU A 234 ? 0.38613 0.30190 0.24720 0.07325  -0.00521 0.04026  1240 GLU A CB  
1989 C CG  A GLU A 234 ? 0.34284 0.30927 0.14572 0.16700  0.01259  0.04334  1240 GLU A CG  
1990 C CG  B GLU A 234 ? 0.42019 0.31482 0.25096 0.08211  0.00490  0.03733  1240 GLU A CG  
1991 C CD  A GLU A 234 ? 0.37447 0.32263 0.15087 0.17276  0.02101  0.04805  1240 GLU A CD  
1992 C CD  B GLU A 234 ? 0.44522 0.32502 0.25271 0.10019  0.00992  0.03857  1240 GLU A CD  
1993 O OE1 A GLU A 234 ? 0.38247 0.32470 0.15828 0.18700  0.01918  0.04421  1240 GLU A OE1 
1994 O OE1 B GLU A 234 ? 0.45369 0.32055 0.25317 0.10855  0.01202  0.04061  1240 GLU A OE1 
1995 O OE2 A GLU A 234 ? 0.38829 0.32499 0.15768 0.17335  0.02201  0.05321  1240 GLU A OE2 
1996 O OE2 B GLU A 234 ? 0.45493 0.33737 0.25244 0.11511  0.00935  0.03976  1240 GLU A OE2 
1997 N N   A GLN A 235 ? 0.21215 0.20919 0.15746 0.04767  -0.00786 0.02891  1241 GLN A N   
1998 N N   B GLN A 235 ? 0.24608 0.20083 0.21241 0.02449  -0.04806 0.02253  1241 GLN A N   
1999 C CA  A GLN A 235 ? 0.19024 0.21277 0.17173 0.03933  -0.01388 0.03286  1241 GLN A CA  
2000 C CA  B GLN A 235 ? 0.21768 0.18286 0.19955 0.02063  -0.06286 0.01860  1241 GLN A CA  
2001 C C   A GLN A 235 ? 0.17750 0.22960 0.19288 0.03330  -0.01927 0.04935  1241 GLN A C   
2002 C C   B GLN A 235 ? 0.22292 0.17376 0.19741 0.02694  -0.06360 0.01899  1241 GLN A C   
2003 O O   A GLN A 235 ? 0.15526 0.24787 0.18822 0.03317  -0.00719 0.05593  1241 GLN A O   
2004 O O   B GLN A 235 ? 0.23798 0.18248 0.19500 0.03489  -0.06667 0.02405  1241 GLN A O   
2005 C CB  A GLN A 235 ? 0.17357 0.19931 0.16792 0.02201  -0.00861 0.02759  1241 GLN A CB  
2006 C CB  B GLN A 235 ? 0.20691 0.18220 0.19068 0.00117  -0.06856 0.01029  1241 GLN A CB  
2007 C CG  A GLN A 235 ? 0.18072 0.18712 0.16687 0.02766  -0.00953 0.01888  1241 GLN A CG  
2008 C CG  B GLN A 235 ? 0.21123 0.19377 0.18474 0.00726  -0.06581 0.01144  1241 GLN A CG  
2009 C CD  A GLN A 235 ? 0.18233 0.17619 0.16270 0.02737  -0.00864 0.01304  1241 GLN A CD  
2010 C CD  B GLN A 235 ? 0.21839 0.18708 0.18242 -0.00122 -0.05907 0.01068  1241 GLN A CD  
2011 O OE1 A GLN A 235 ? 0.17229 0.17400 0.15944 0.03379  -0.00249 0.01965  1241 GLN A OE1 
2012 O OE1 B GLN A 235 ? 0.21990 0.15692 0.17777 -0.00420 -0.05256 0.01648  1241 GLN A OE1 
2013 N NE2 A GLN A 235 ? 0.20140 0.19637 0.16584 0.02419  -0.01578 0.00306  1241 GLN A NE2 
2014 N NE2 B GLN A 235 ? 0.20511 0.18539 0.18307 -0.01290 -0.06471 0.01044  1241 GLN A NE2 
2015 N N   A LYS A 236 ? 0.20192 0.25961 0.22177 0.05614  -0.03670 0.04467  1242 LYS A N   
2016 N N   B LYS A 236 ? 0.18624 0.16750 0.19714 0.02319  -0.07316 0.02131  1242 LYS A N   
2017 C CA  A LYS A 236 ? 0.22873 0.28562 0.25388 0.06561  -0.04221 0.04767  1242 LYS A CA  
2018 C CA  B LYS A 236 ? 0.17605 0.18569 0.20104 0.02537  -0.07645 0.03864  1242 LYS A CA  
2019 C C   A LYS A 236 ? 0.21056 0.28061 0.24539 0.08637  -0.04520 0.04890  1242 LYS A C   
2020 C C   B LYS A 236 ? 0.15296 0.20051 0.20668 0.00942  -0.07349 0.04153  1242 LYS A C   
2021 O O   A LYS A 236 ? 0.25533 0.29409 0.24427 0.10971  -0.04298 0.04333  1242 LYS A O   
2022 O O   B LYS A 236 ? 0.18876 0.21952 0.20867 0.02805  -0.06466 0.04373  1242 LYS A O   
2033 N N   A ASN A 237 ? 0.18349 0.25019 0.24004 0.08395  -0.04994 0.04547  1243 ASN A N   
2034 N N   B ASN A 237 ? 0.15156 0.24910 0.21703 0.03019  -0.06224 0.04122  1243 ASN A N   
2035 C CA  A ASN A 237 ? 0.16371 0.24081 0.23871 0.07442  -0.05360 0.03666  1243 ASN A CA  
2036 C CA  B ASN A 237 ? 0.14164 0.28488 0.22788 0.02177  -0.04467 0.05352  1243 ASN A CA  
2037 C C   A ASN A 237 ? 0.19674 0.25071 0.24471 0.08273  -0.06157 0.03931  1243 ASN A C   
2038 C C   B ASN A 237 ? 0.16512 0.28225 0.23982 0.02950  -0.02435 0.05825  1243 ASN A C   
2039 O O   A ASN A 237 ? 0.21266 0.25632 0.24229 0.05860  -0.05130 0.04170  1243 ASN A O   
2040 O O   B ASN A 237 ? 0.18062 0.27185 0.23570 0.05836  -0.01279 0.07142  1243 ASN A O   
2041 C CB  A ASN A 237 ? 0.19062 0.21861 0.23111 0.02619  -0.05333 0.01749  1243 ASN A CB  
2042 C CB  B ASN A 237 ? 0.14577 0.33307 0.22927 0.04020  -0.04698 0.06659  1243 ASN A CB  
2043 C CG  A ASN A 237 ? 0.20885 0.23860 0.22509 0.03922  -0.06959 0.01683  1243 ASN A CG  
2044 C CG  B ASN A 237 ? 0.19437 0.39794 0.23258 0.08254  -0.04292 0.08028  1243 ASN A CG  
2045 O OD1 A ASN A 237 ? 0.21986 0.27741 0.22592 0.07181  -0.06001 0.02776  1243 ASN A OD1 
2046 O OD1 B ASN A 237 ? 0.25113 0.45641 0.23372 0.12954  -0.04439 0.07128  1243 ASN A OD1 
2047 N ND2 A ASN A 237 ? 0.22046 0.22058 0.22229 0.00324  -0.09406 -0.00173 1243 ASN A ND2 
2048 N ND2 B ASN A 237 ? 0.18005 0.37906 0.23665 0.05414  -0.03637 0.09139  1243 ASN A ND2 
2049 N N   A ARG A 238 ? 0.22711 0.26099 0.25576 0.06125  -0.06463 0.04227  1244 ARG A N   
2050 N N   B ARG A 238 ? 0.19305 0.30043 0.25647 0.03039  -0.01751 0.05885  1244 ARG A N   
2051 C CA  A ARG A 238 ? 0.25603 0.29963 0.27067 0.07634  -0.04745 0.04345  1244 ARG A CA  
2052 C CA  B ARG A 238 ? 0.25519 0.32568 0.27579 0.05479  -0.01317 0.04773  1244 ARG A CA  
2053 C C   A ARG A 238 ? 0.27044 0.36517 0.25871 0.09384  -0.03399 0.03814  1244 ARG A C   
2054 C C   B ARG A 238 ? 0.27665 0.36496 0.25530 0.09803  -0.01145 0.03415  1244 ARG A C   
2055 O O   A ARG A 238 ? 0.29430 0.40827 0.25635 0.14043  -0.03103 0.04573  1244 ARG A O   
2056 O O   B ARG A 238 ? 0.29120 0.37732 0.25370 0.11630  -0.00865 0.03724  1244 ARG A O   
2071 N N   A SER A 239 ? 0.28218 0.39849 0.25272 0.04708  -0.01988 0.02157  1245 SER A N   
2072 N N   B SER A 239 ? 0.27857 0.39124 0.23685 0.11396  -0.01790 0.01756  1245 SER A N   
2073 C CA  A SER A 239 ? 0.32328 0.43613 0.25156 0.03511  -0.00126 0.01115  1245 SER A CA  
2074 C CA  B SER A 239 ? 0.28716 0.41165 0.22081 0.11522  -0.02685 0.00481  1245 SER A CA  
2075 C C   A SER A 239 ? 0.33738 0.45791 0.24808 0.02507  -0.00105 0.00351  1245 SER A C   
2076 C C   B SER A 239 ? 0.27617 0.40110 0.20483 0.10536  -0.04419 -0.00311 1245 SER A C   
2077 O O   A SER A 239 ? 0.38262 0.50908 0.25380 0.05214  0.00117  -0.00519 1245 SER A O   
2078 O O   B SER A 239 ? 0.29457 0.43581 0.20194 0.13486  -0.04985 -0.00274 1245 SER A O   
2079 C CB  A SER A 239 ? 0.34076 0.44393 0.25359 0.04598  0.00628  0.00334  1245 SER A CB  
2080 C CB  B SER A 239 ? 0.30028 0.43163 0.22075 0.12281  -0.02114 0.00213  1245 SER A CB  
2081 O OG  A SER A 239 ? 0.34484 0.44738 0.25581 0.03853  0.00995  -0.00108 1245 SER A OG  
2082 O OG  B SER A 239 ? 0.31927 0.44029 0.22101 0.11995  -0.01649 0.00284  1245 SER A OG  
2083 N N   A GLY A 240 ? 0.29911 0.42168 0.23640 0.01685  -0.00572 0.00647  1246 GLY A N   
2084 N N   B GLY A 240 ? 0.23887 0.36637 0.19418 0.07210  -0.04976 -0.01003 1246 GLY A N   
2085 C CA  A GLY A 240 ? 0.26478 0.39689 0.22786 0.03681  -0.01645 0.00965  1246 GLY A CA  
2086 C CA  B GLY A 240 ? 0.20776 0.34810 0.18965 0.07415  -0.05114 -0.01207 1246 GLY A CA  
2087 C C   A GLY A 240 ? 0.22697 0.37768 0.21945 0.03891  -0.02944 0.01162  1246 GLY A C   
2088 C C   B GLY A 240 ? 0.20485 0.35303 0.18759 0.09075  -0.05552 -0.00937 1246 GLY A C   
2089 O O   A GLY A 240 ? 0.20306 0.40011 0.21723 0.07136  -0.05762 0.00959  1246 GLY A O   
2090 O O   B GLY A 240 ? 0.18342 0.36824 0.18689 0.06877  -0.06722 -0.01140 1246 GLY A O   
2091 N N   A GLY A 241 ? 0.20413 0.33956 0.21233 0.04286  -0.03148 0.01001  1247 GLY A N   
2092 N N   B GLY A 241 ? 0.20583 0.33120 0.18813 0.07793  -0.04428 -0.00607 1247 GLY A N   
2093 C CA  A GLY A 241 ? 0.19552 0.31246 0.20436 0.02774  -0.02816 0.01888  1247 GLY A CA  
2094 C CA  B GLY A 241 ? 0.21011 0.31590 0.19273 0.06162  -0.03848 -0.00780 1247 GLY A CA  
2095 C C   A GLY A 241 ? 0.20001 0.27893 0.19603 0.02596  -0.03052 0.02515  1247 GLY A C   
2096 C C   B GLY A 241 ? 0.19098 0.29735 0.19544 0.04531  -0.03496 -0.00913 1247 GLY A C   
2097 O O   A GLY A 241 ? 0.22360 0.26231 0.19324 0.02316  -0.03645 0.03217  1247 GLY A O   
2098 O O   B GLY A 241 ? 0.17845 0.29261 0.18992 0.01764  -0.02211 -0.01468 1247 GLY A O   
2099 N N   A LYS A 242 ? 0.17323 0.26839 0.19023 0.01588  -0.03971 0.01709  1248 LYS A N   
2100 N N   B LYS A 242 ? 0.18311 0.26550 0.20082 0.05432  -0.04574 -0.00423 1248 LYS A N   
2101 C CA  A LYS A 242 ? 0.17107 0.24348 0.18829 0.01248  -0.04062 0.01674  1248 LYS A CA  
2102 C CA  B LYS A 242 ? 0.18520 0.23436 0.20759 0.04086  -0.04724 0.00359  1248 LYS A CA  
2103 C C   A LYS A 242 ? 0.15955 0.23853 0.17329 0.01833  -0.03064 0.01990  1248 LYS A C   
2104 C C   B LYS A 242 ? 0.18032 0.23876 0.20372 0.04187  -0.04170 0.01165  1248 LYS A C   
2105 O O   A LYS A 242 ? 0.15533 0.25629 0.17410 0.02833  -0.02760 0.01893  1248 LYS A O   
2106 O O   B LYS A 242 ? 0.17632 0.27044 0.20532 0.05879  -0.04171 0.00213  1248 LYS A O   
2117 N N   A MET A 243 ? 0.14708 0.21347 0.15848 0.02881  -0.03463 0.01864  1249 MET A N   
2118 N N   B MET A 243 ? 0.17356 0.21442 0.19974 0.04412  -0.04303 0.02063  1249 MET A N   
2119 C CA  A MET A 243 ? 0.15886 0.20481 0.14656 0.00827  -0.02141 0.02554  1249 MET A CA  
2120 C CA  B MET A 243 ? 0.16683 0.19925 0.19187 0.03090  -0.05155 0.02475  1249 MET A CA  
2121 C C   A MET A 243 ? 0.13817 0.20532 0.13667 -0.00735 -0.01513 0.02018  1249 MET A C   
2122 C C   B MET A 243 ? 0.17628 0.18639 0.16866 0.02542  -0.05381 0.03003  1249 MET A C   
2123 O O   A MET A 243 ? 0.14866 0.21615 0.13051 0.01144  -0.01181 0.01715  1249 MET A O   
2124 O O   B MET A 243 ? 0.19378 0.19544 0.16137 0.01417  -0.05350 0.03527  1249 MET A O   
2125 C CB  A MET A 243 ? 0.18476 0.20911 0.14661 -0.00874 -0.01885 0.02699  1249 MET A CB  
2126 C CB  B MET A 243 ? 0.19924 0.18757 0.20610 0.01984  -0.04877 0.02599  1249 MET A CB  
2127 C CG  A MET A 243 ? 0.19869 0.22160 0.14875 -0.01163 -0.01802 0.01972  1249 MET A CG  
2128 C CG  B MET A 243 ? 0.20269 0.20287 0.21809 0.00342  -0.06171 0.02552  1249 MET A CG  
2129 S SD  A MET A 243 ? 0.25513 0.23629 0.15516 -0.05197 -0.00586 0.01042  1249 MET A SD  
2130 S SD  B MET A 243 ? 0.19759 0.26738 0.23187 0.01591  -0.05928 0.01918  1249 MET A SD  
2131 C CE  A MET A 243 ? 0.26598 0.27659 0.16348 -0.03498 -0.01322 0.00033  1249 MET A CE  
2132 C CE  B MET A 243 ? 0.18453 0.24855 0.23067 0.02609  -0.07060 0.02422  1249 MET A CE  
2133 N N   A TYR A 244 ? 0.15654 0.19658 0.13525 -0.01000 -0.01774 0.01415  1250 TYR A N   
2134 N N   B TYR A 244 ? 0.18510 0.17862 0.15810 0.02305  -0.05014 0.02246  1250 TYR A N   
2135 C CA  A TYR A 244 ? 0.15381 0.19544 0.14101 -0.01765 -0.01073 0.02150  1250 TYR A CA  
2136 C CA  B TYR A 244 ? 0.18131 0.19160 0.15009 0.00752  -0.03879 0.01364  1250 TYR A CA  
2137 C C   A TYR A 244 ? 0.16112 0.19324 0.12907 0.00553  -0.01563 0.03673  1250 TYR A C   
2138 C C   B TYR A 244 ? 0.16671 0.18124 0.12529 0.00555  -0.04414 0.01386  1250 TYR A C   
2139 O O   A TYR A 244 ? 0.14456 0.20976 0.12878 0.01004  -0.01448 0.04342  1250 TYR A O   
2140 O O   B TYR A 244 ? 0.17213 0.17438 0.12328 0.00512  -0.04450 0.01671  1250 TYR A O   
2141 C CB  A TYR A 244 ? 0.15875 0.23262 0.15923 0.00543  -0.00618 0.01389  1250 TYR A CB  
2142 C CB  B TYR A 244 ? 0.17642 0.23013 0.16666 0.01836  -0.04035 0.00823  1250 TYR A CB  
2143 C CG  A TYR A 244 ? 0.15470 0.26493 0.17486 0.00239  -0.00153 0.01327  1250 TYR A CG  
2144 C CG  B TYR A 244 ? 0.17938 0.26523 0.18229 0.02177  -0.03604 0.00535  1250 TYR A CG  
2145 C CD1 A TYR A 244 ? 0.15398 0.28625 0.18226 -0.00737 0.00071  0.00785  1250 TYR A CD1 
2146 C CD1 B TYR A 244 ? 0.19059 0.29228 0.18841 0.03082  -0.03483 0.00516  1250 TYR A CD1 
2147 C CD2 A TYR A 244 ? 0.16540 0.28987 0.18486 0.00058  -0.00260 0.01938  1250 TYR A CD2 
2148 C CD2 B TYR A 244 ? 0.19562 0.29069 0.18936 0.04906  -0.03280 0.01052  1250 TYR A CD2 
2149 C CE1 A TYR A 244 ? 0.16888 0.32302 0.19032 -0.00148 0.00404  0.00917  1250 TYR A CE1 
2150 C CE1 B TYR A 244 ? 0.20746 0.31652 0.19452 0.03400  -0.03063 0.00377  1250 TYR A CE1 
2151 C CE2 A TYR A 244 ? 0.17669 0.31238 0.19383 -0.01257 -0.00208 0.01242  1250 TYR A CE2 
2152 C CE2 B TYR A 244 ? 0.20157 0.32145 0.19494 0.05993  -0.03118 0.01260  1250 TYR A CE2 
2153 C CZ  A TYR A 244 ? 0.17999 0.33519 0.19844 -0.00123 0.00379  0.00856  1250 TYR A CZ  
2154 C CZ  B TYR A 244 ? 0.21135 0.34759 0.19892 0.05532  -0.02674 0.00583  1250 TYR A CZ  
2155 O OH  A TYR A 244 ? 0.19789 0.35008 0.20903 0.00543  0.00908  0.00655  1250 TYR A OH  
2156 O OH  B TYR A 244 ? 0.22195 0.38041 0.20474 0.07207  -0.02597 0.00245  1250 TYR A OH  
2157 N N   A VAL A 245 ? 0.16281 0.18036 0.12178 0.00314  -0.02163 0.03484  1251 VAL A N   
2158 N N   B VAL A 245 ? 0.16370 0.16133 0.10745 0.01628  -0.03216 0.01899  1251 VAL A N   
2159 C CA  A VAL A 245 ? 0.16449 0.17886 0.12063 0.00174  -0.01326 0.03601  1251 VAL A CA  
2160 C CA  B VAL A 245 ? 0.18006 0.15961 0.09225 0.01932  -0.03278 0.03022  1251 VAL A CA  
2161 C C   A VAL A 245 ? 0.16769 0.17195 0.12357 -0.00417 -0.00729 0.03605  1251 VAL A C   
2162 C C   B VAL A 245 ? 0.17684 0.14891 0.08932 0.00549  -0.02820 0.04450  1251 VAL A C   
2163 O O   A VAL A 245 ? 0.18009 0.18243 0.13011 0.00583  -0.00861 0.05230  1251 VAL A O   
2164 O O   B VAL A 245 ? 0.19068 0.15051 0.08872 0.00080  -0.02640 0.04816  1251 VAL A O   
2165 C CB  A VAL A 245 ? 0.14945 0.18099 0.12245 0.00503  -0.01628 0.02583  1251 VAL A CB  
2166 C CB  B VAL A 245 ? 0.19002 0.16630 0.08634 0.01983  -0.03297 0.03354  1251 VAL A CB  
2167 C CG1 A VAL A 245 ? 0.14976 0.16322 0.12232 -0.00007 -0.01847 0.02189  1251 VAL A CG1 
2168 C CG1 B VAL A 245 ? 0.21254 0.17169 0.08355 0.02554  -0.03371 0.03080  1251 VAL A CG1 
2169 C CG2 A VAL A 245 ? 0.15080 0.19971 0.12534 0.01147  0.00328  0.02711  1251 VAL A CG2 
2170 C CG2 B VAL A 245 ? 0.17936 0.15882 0.08767 0.01239  -0.03191 0.02928  1251 VAL A CG2 
2171 N N   A GLN A 246 ? 0.16890 0.16472 0.11863 0.00619  -0.00832 0.03833  1252 GLN A N   
2172 N N   B GLN A 246 ? 0.18133 0.15170 0.09420 0.00667  -0.01994 0.03809  1252 GLN A N   
2173 C CA  A GLN A 246 ? 0.17750 0.16659 0.12146 0.01136  0.00268  0.03906  1252 GLN A CA  
2174 C CA  B GLN A 246 ? 0.20011 0.16368 0.09782 0.01220  -0.01817 0.04164  1252 GLN A CA  
2175 C C   A GLN A 246 ? 0.16476 0.16671 0.12382 0.01332  -0.00497 0.04452  1252 GLN A C   
2176 C C   B GLN A 246 ? 0.22148 0.15302 0.09662 0.01202  -0.01751 0.04874  1252 GLN A C   
2177 O O   A GLN A 246 ? 0.18130 0.16513 0.12675 0.00738  -0.00025 0.03569  1252 GLN A O   
2178 O O   B GLN A 246 ? 0.23244 0.15123 0.09376 -0.00393 -0.01734 0.05314  1252 GLN A O   
2179 C CB  A GLN A 246 ? 0.19903 0.14495 0.12325 -0.00185 0.00083  0.02005  1252 GLN A CB  
2180 C CB  B GLN A 246 ? 0.18760 0.15752 0.09995 -0.01158 -0.02881 0.03657  1252 GLN A CB  
2181 C CG  A GLN A 246 ? 0.19466 0.17296 0.12615 -0.02168 -0.01033 0.01739  1252 GLN A CG  
2182 C CG  B GLN A 246 ? 0.18152 0.14284 0.10248 -0.03304 -0.04136 0.02385  1252 GLN A CG  
2183 C CD  A GLN A 246 ? 0.18000 0.19359 0.13132 -0.02300 -0.02052 0.02689  1252 GLN A CD  
2184 C CD  B GLN A 246 ? 0.19063 0.15660 0.10915 -0.04026 -0.03534 0.01723  1252 GLN A CD  
2185 O OE1 A GLN A 246 ? 0.17968 0.19180 0.12875 -0.01962 -0.02104 0.02760  1252 GLN A OE1 
2186 O OE1 B GLN A 246 ? 0.19254 0.16965 0.11063 -0.02672 -0.02568 0.02662  1252 GLN A OE1 
2187 N NE2 A GLN A 246 ? 0.16690 0.20613 0.13592 -0.02060 -0.03106 0.02531  1252 GLN A NE2 
2188 N NE2 B GLN A 246 ? 0.19786 0.17350 0.11608 -0.00364 -0.03383 0.01476  1252 GLN A NE2 
2189 N N   A ASP A 247 ? 0.14898 0.16052 0.12567 -0.00725 -0.00862 0.05535  1253 ASP A N   
2190 N N   B ASP A 247 ? 0.26366 0.15749 0.10118 0.02450  -0.02277 0.04388  1253 ASP A N   
2191 C CA  A ASP A 247 ? 0.16552 0.17959 0.13050 -0.01496 -0.00212 0.05482  1253 ASP A CA  
2192 C CA  B ASP A 247 ? 0.29129 0.17753 0.10726 0.03154  -0.02935 0.03756  1253 ASP A CA  
2193 C C   A ASP A 247 ? 0.17859 0.22075 0.13218 -0.01125 -0.00984 0.05634  1253 ASP A C   
2194 C C   B ASP A 247 ? 0.30626 0.20408 0.10537 0.04474  -0.03431 0.03913  1253 ASP A C   
2195 O O   A ASP A 247 ? 0.17504 0.20177 0.13790 -0.03098 -0.00623 0.06278  1253 ASP A O   
2196 O O   B ASP A 247 ? 0.31295 0.17091 0.10524 0.01812  -0.03686 0.02765  1253 ASP A O   
2197 C CB  A ASP A 247 ? 0.14554 0.18920 0.12645 -0.02306 -0.00740 0.04113  1253 ASP A CB  
2198 C CB  B ASP A 247 ? 0.29721 0.19138 0.11285 0.04247  -0.02538 0.04525  1253 ASP A CB  
2199 C CG  A ASP A 247 ? 0.16825 0.21820 0.12556 -0.00406 -0.01475 0.03938  1253 ASP A CG  
2200 C CG  B ASP A 247 ? 0.29562 0.23222 0.11931 0.05584  -0.02719 0.06005  1253 ASP A CG  
2201 O OD1 A ASP A 247 ? 0.19480 0.23357 0.12651 0.00772  -0.01618 0.02607  1253 ASP A OD1 
2202 O OD1 B ASP A 247 ? 0.32493 0.25998 0.12011 0.02086  -0.02545 0.05645  1253 ASP A OD1 
2203 O OD2 A ASP A 247 ? 0.17002 0.21340 0.12783 0.00065  -0.02291 0.03947  1253 ASP A OD2 
2204 O OD2 B ASP A 247 ? 0.28613 0.30249 0.12614 0.06833  -0.01963 0.06146  1253 ASP A OD2 
2205 N N   A LYS A 248 ? 0.20377 0.27236 0.13043 0.01009  -0.02554 0.05815  1254 LYS A N   
2206 N N   B LYS A 248 ? 0.31397 0.28005 0.11903 0.08338  -0.03442 0.03878  1254 LYS A N   
2207 C CA  A LYS A 248 ? 0.24145 0.32811 0.13279 0.03927  -0.02983 0.06165  1254 LYS A CA  
2208 C CA  B LYS A 248 ? 0.31147 0.31000 0.12114 0.08206  -0.03598 0.04060  1254 LYS A CA  
2209 C C   A LYS A 248 ? 0.22763 0.34668 0.13696 0.05748  -0.02957 0.07431  1254 LYS A C   
2210 C C   B LYS A 248 ? 0.27722 0.32313 0.13149 0.09021  -0.02579 0.05770  1254 LYS A C   
2211 O O   A LYS A 248 ? 0.22332 0.34535 0.14863 0.05491  -0.03968 0.07812  1254 LYS A O   
2212 O O   B LYS A 248 ? 0.28133 0.32044 0.13679 0.11003  -0.01791 0.05600  1254 LYS A O   
2213 C CB  A LYS A 248 ? 0.30700 0.37146 0.13746 0.07394  -0.03256 0.05732  1254 LYS A CB  
2214 C CB  B LYS A 248 ? 0.32327 0.31403 0.11841 0.07110  -0.04703 0.03041  1254 LYS A CB  
2215 C CG  A LYS A 248 ? 0.35834 0.41496 0.14606 0.11227  -0.01507 0.05614  1254 LYS A CG  
2216 C CG  B LYS A 248 ? 0.32902 0.33356 0.11621 0.07679  -0.03823 0.02579  1254 LYS A CG  
2217 C CD  A LYS A 248 ? 0.39373 0.45087 0.15189 0.14380  0.01136  0.04789  1254 LYS A CD  
2218 C CD  B LYS A 248 ? 0.32674 0.31822 0.11430 0.07965  -0.04191 0.01676  1254 LYS A CD  
2219 C CE  A LYS A 248 ? 0.39175 0.45512 0.15315 0.15528  0.02512  0.04250  1254 LYS A CE  
2220 C CE  B LYS A 248 ? 0.28258 0.28423 0.10525 0.04869  -0.05128 0.02041  1254 LYS A CE  
2221 N NZ  A LYS A 248 ? 0.39234 0.45792 0.15397 0.15736  0.02361  0.04245  1254 LYS A NZ  
2222 N NZ  B LYS A 248 ? 0.26880 0.28116 0.10854 0.03189  -0.05066 0.01418  1254 LYS A NZ  
2223 N N   . ILE A 249 ? 0.24634 0.33617 0.13138 0.06991  -0.01568 0.07429  1255 ILE A N   
2224 C CA  . ILE A 249 ? 0.24624 0.33497 0.13749 0.08353  0.00524  0.08272  1255 ILE A CA  
2225 C C   . ILE A 249 ? 0.25983 0.32171 0.13706 0.09515  0.00075  0.07621  1255 ILE A C   
2226 O O   . ILE A 249 ? 0.27734 0.27587 0.14204 0.07695  0.00967  0.07797  1255 ILE A O   
2227 C CB  . ILE A 249 ? 0.21884 0.30871 0.14953 0.07053  0.01485  0.09943  1255 ILE A CB  
2228 C CG1 . ILE A 249 ? 0.20995 0.31368 0.15738 0.06467  -0.00838 0.09473  1255 ILE A CG1 
2229 C CG2 . ILE A 249 ? 0.24350 0.31795 0.15715 0.07555  0.03945  0.10651  1255 ILE A CG2 
2230 C CD1 . ILE A 249 ? 0.20279 0.31503 0.15992 0.05192  -0.01435 0.09667  1255 ILE A CD1 
2231 N N   . GLU A 250 ? 0.26101 0.32969 0.13709 0.09880  -0.00335 0.07225  1256 GLU A N   
2232 C CA  . GLU A 250 ? 0.29396 0.33185 0.13197 0.10967  -0.00824 0.05695  1256 GLU A CA  
2233 C C   . GLU A 250 ? 0.32434 0.30722 0.12581 0.12344  -0.00725 0.03912  1256 GLU A C   
2234 O O   . GLU A 250 ? 0.34176 0.30480 0.12050 0.10464  -0.00514 0.04052  1256 GLU A O   
2235 C CB  . GLU A 250 ? 0.29231 0.36228 0.13389 0.10825  -0.02175 0.04820  1256 GLU A CB  
2236 C CG  . GLU A 250 ? 0.32040 0.39706 0.14557 0.10905  -0.03403 0.04861  1256 GLU A CG  
2237 C CD  . GLU A 250 ? 0.38344 0.45769 0.16722 0.13248  -0.03212 0.05700  1256 GLU A CD  
2238 O OE1 . GLU A 250 ? 0.44185 0.49148 0.17133 0.13408  -0.02025 0.06156  1256 GLU A OE1 
2239 O OE2 . GLU A 250 ? 0.39350 0.48332 0.18147 0.14737  -0.03564 0.06046  1256 GLU A OE2 
2240 N N   . GLU A 251 ? 0.36163 0.29718 0.12885 0.14666  -0.00450 0.02445  1257 GLU A N   
2241 C CA  . GLU A 251 ? 0.39012 0.28513 0.13211 0.14358  -0.01158 0.02084  1257 GLU A CA  
2242 C C   . GLU A 251 ? 0.39291 0.25057 0.12831 0.12009  -0.00800 0.02852  1257 GLU A C   
2243 O O   . GLU A 251 ? 0.43715 0.25301 0.14205 0.12064  -0.00935 0.03389  1257 GLU A O   
2244 C CB  . GLU A 251 ? 0.40767 0.32903 0.14391 0.18076  -0.01941 0.00292  1257 GLU A CB  
2245 C CG  . GLU A 251 ? 0.42404 0.37471 0.15874 0.21943  -0.02368 -0.01352 1257 GLU A CG  
2246 C CD  . GLU A 251 ? 0.43481 0.43164 0.17558 0.24154  -0.03647 -0.03613 1257 GLU A CD  
2247 O OE1 . GLU A 251 ? 0.43814 0.45437 0.18046 0.23624  -0.04441 -0.04282 1257 GLU A OE1 
2248 O OE2 . GLU A 251 ? 0.46671 0.47309 0.18839 0.24323  -0.03291 -0.04752 1257 GLU A OE2 
2249 N N   . TYR A 252 ? 0.34204 0.23232 0.10638 0.10600  -0.01471 0.01046  1258 TYR A N   
2250 C CA  . TYR A 252 ? 0.31444 0.21993 0.09214 0.07590  -0.01666 0.00590  1258 TYR A CA  
2251 C C   . TYR A 252 ? 0.28727 0.20720 0.08900 0.04837  -0.01760 0.01182  1258 TYR A C   
2252 O O   . TYR A 252 ? 0.28460 0.19770 0.08854 0.05115  -0.02690 0.00287  1258 TYR A O   
2253 C CB  . TYR A 252 ? 0.30993 0.20764 0.09251 0.06788  -0.02570 0.00926  1258 TYR A CB  
2254 C CG  . TYR A 252 ? 0.31584 0.19208 0.09754 0.06078  -0.03087 0.01758  1258 TYR A CG  
2255 C CD1 . TYR A 252 ? 0.34162 0.18282 0.09757 0.03236  -0.02242 0.02404  1258 TYR A CD1 
2256 C CD2 . TYR A 252 ? 0.32082 0.19863 0.10156 0.06080  -0.03671 0.01836  1258 TYR A CD2 
2257 C CE1 . TYR A 252 ? 0.34905 0.19227 0.10062 0.03929  -0.02530 0.02360  1258 TYR A CE1 
2258 C CE2 . TYR A 252 ? 0.33448 0.19750 0.10650 0.07456  -0.03241 0.01790  1258 TYR A CE2 
2259 C CZ  . TYR A 252 ? 0.34920 0.17971 0.10179 0.05834  -0.02947 0.01373  1258 TYR A CZ  
2260 O OH  . TYR A 252 ? 0.37355 0.17472 0.10001 0.03332  -0.01723 0.01002  1258 TYR A OH  
2261 N N   . SER A 253 ? 0.27137 0.20996 0.09258 0.01601  -0.01124 0.00456  1259 SER A N   
2262 C CA  A SER A 253 ? 0.26424 0.23569 0.09754 0.02037  -0.00449 -0.00475 1259 SER A CA  
2263 C CA  B SER A 253 ? 0.26590 0.21815 0.09436 0.01000  -0.00431 0.00075  1259 SER A CA  
2264 C C   . SER A 253 ? 0.25166 0.19341 0.09249 0.01352  -0.00920 0.00295  1259 SER A C   
2265 O O   . SER A 253 ? 0.24179 0.19460 0.09013 0.00302  -0.01362 0.00120  1259 SER A O   
2266 C CB  A SER A 253 ? 0.25549 0.29131 0.10971 0.01902  -0.00379 -0.01020 1259 SER A CB  
2267 C CB  B SER A 253 ? 0.26190 0.24273 0.09897 -0.00754 -0.00109 -0.00034 1259 SER A CB  
2268 O OG  A SER A 253 ? 0.26966 0.33951 0.11657 0.06970  -0.01003 -0.00862 1259 SER A OG  
2269 O OG  B SER A 253 ? 0.26692 0.25862 0.10188 0.00306  0.00109  -0.00254 1259 SER A OG  
2270 N N   . ASP A 254 ? 0.25121 0.19349 0.09636 0.01321  -0.00442 0.01301  1260 ASP A N   
2271 C CA  . ASP A 254 ? 0.24276 0.18504 0.10350 0.01607  -0.00294 0.03603  1260 ASP A CA  
2272 C C   . ASP A 254 ? 0.24215 0.17527 0.09745 0.00854  -0.01730 0.02010  1260 ASP A C   
2273 O O   . ASP A 254 ? 0.23574 0.17902 0.09428 -0.00032 -0.01093 0.02701  1260 ASP A O   
2274 C CB  . ASP A 254 ? 0.25418 0.19737 0.12281 0.02386  0.00857  0.02939  1260 ASP A CB  
2275 C CG  . ASP A 254 ? 0.30003 0.19933 0.14509 0.00395  0.02820  0.01507  1260 ASP A CG  
2276 O OD1 . ASP A 254 ? 0.29968 0.24161 0.15835 -0.00037 0.03299  -0.00063 1260 ASP A OD1 
2277 O OD2 . ASP A 254 ? 0.36180 0.27726 0.16574 -0.00793 0.03396  -0.02324 1260 ASP A OD2 
2278 N N   . GLU A 255 ? 0.26545 0.17246 0.09084 0.00010  -0.02437 0.01567  1261 GLU A N   
2279 C CA  . GLU A 255 ? 0.27115 0.17159 0.08925 -0.01234 -0.03020 0.01796  1261 GLU A CA  
2280 C C   . GLU A 255 ? 0.24464 0.16195 0.08507 -0.00886 -0.01789 0.02072  1261 GLU A C   
2281 O O   . GLU A 255 ? 0.22635 0.16799 0.09063 -0.02390 -0.01137 0.01838  1261 GLU A O   
2282 C CB  . GLU A 255 ? 0.30659 0.17434 0.09763 -0.02929 -0.03265 0.00732  1261 GLU A CB  
2283 C CG  . GLU A 255 ? 0.33676 0.18272 0.10717 -0.04601 -0.02335 0.00580  1261 GLU A CG  
2284 C CD  . GLU A 255 ? 0.37215 0.22581 0.12005 -0.03044 -0.01535 0.01257  1261 GLU A CD  
2285 O OE1 . GLU A 255 ? 0.38345 0.31803 0.12465 -0.00350 -0.01021 0.00966  1261 GLU A OE1 
2286 O OE2 . GLU A 255 ? 0.40293 0.21410 0.13013 -0.00367 -0.01061 0.00113  1261 GLU A OE2 
2287 N N   . ILE A 256 ? 0.23185 0.16173 0.08445 -0.01578 -0.01301 0.01183  1262 ILE A N   
2288 C CA  . ILE A 256 ? 0.21599 0.18527 0.08224 -0.00993 -0.01602 0.01274  1262 ILE A CA  
2289 C C   . ILE A 256 ? 0.20241 0.18343 0.08017 -0.00459 -0.01720 0.02118  1262 ILE A C   
2290 O O   . ILE A 256 ? 0.20461 0.18715 0.08137 -0.01485 -0.01486 0.01885  1262 ILE A O   
2291 C CB  . ILE A 256 ? 0.21848 0.20521 0.08761 -0.01324 -0.01368 0.00513  1262 ILE A CB  
2292 C CG1 . ILE A 256 ? 0.24348 0.22761 0.09461 -0.00471 -0.00931 -0.00816 1262 ILE A CG1 
2293 C CG2 . ILE A 256 ? 0.21480 0.20173 0.09453 -0.01140 -0.01797 0.01256  1262 ILE A CG2 
2294 C CD1 . ILE A 256 ? 0.26481 0.25180 0.10126 0.01369  -0.00074 0.00636  1262 ILE A CD1 
2295 N N   . PHE A 257 ? 0.20686 0.19692 0.08018 -0.01039 -0.01284 0.01832  1263 PHE A N   
2296 C CA  . PHE A 257 ? 0.20641 0.17421 0.08213 -0.02448 -0.01757 0.01490  1263 PHE A CA  
2297 C C   . PHE A 257 ? 0.21233 0.17488 0.07259 -0.02380 -0.01273 0.01435  1263 PHE A C   
2298 O O   . PHE A 257 ? 0.21004 0.18739 0.07409 -0.00735 -0.01290 0.01618  1263 PHE A O   
2299 C CB  . PHE A 257 ? 0.20558 0.21576 0.09561 -0.02875 -0.02412 0.01738  1263 PHE A CB  
2300 C CG  . PHE A 257 ? 0.21632 0.20551 0.11573 -0.02719 -0.02515 0.01190  1263 PHE A CG  
2301 C CD1 . PHE A 257 ? 0.22314 0.25722 0.12785 -0.04230 -0.01567 0.01345  1263 PHE A CD1 
2302 C CD2 . PHE A 257 ? 0.22493 0.22457 0.12764 -0.02500 -0.03357 0.00567  1263 PHE A CD2 
2303 C CE1 . PHE A 257 ? 0.24147 0.28308 0.14009 -0.01455 -0.02162 0.01182  1263 PHE A CE1 
2304 C CE2 . PHE A 257 ? 0.23363 0.23595 0.13787 -0.01681 -0.04410 0.00643  1263 PHE A CE2 
2305 C CZ  . PHE A 257 ? 0.22158 0.26845 0.14406 -0.02162 -0.03724 0.01359  1263 PHE A CZ  
2306 N N   . LYS A 258 ? 0.22619 0.18090 0.07566 -0.02172 -0.00029 0.02029  1264 LYS A N   
2307 C CA  A LYS A 258 ? 0.21868 0.16778 0.08425 -0.02318 0.00620  0.01757  1264 LYS A CA  
2308 C CA  B LYS A 258 ? 0.21415 0.17383 0.07980 -0.02212 0.00203  0.01510  1264 LYS A CA  
2309 C C   . LYS A 258 ? 0.20399 0.16613 0.07973 -0.03806 0.00385  0.01105  1264 LYS A C   
2310 O O   . LYS A 258 ? 0.20145 0.17816 0.08322 -0.02945 0.00371  0.01279  1264 LYS A O   
2311 C CB  A LYS A 258 ? 0.25363 0.15888 0.10188 -0.02465 0.01093  0.02669  1264 LYS A CB  
2312 C CB  B LYS A 258 ? 0.21587 0.17750 0.08452 -0.02008 0.00341  0.01520  1264 LYS A CB  
2313 C CG  A LYS A 258 ? 0.30297 0.17693 0.11746 0.00232  0.01897  0.04376  1264 LYS A CG  
2314 C CG  B LYS A 258 ? 0.22029 0.18517 0.08780 -0.00820 0.00620  0.01546  1264 LYS A CG  
2315 C CD  A LYS A 258 ? 0.34673 0.18010 0.12861 0.00509  0.02450  0.05619  1264 LYS A CD  
2316 C CD  B LYS A 258 ? 0.22739 0.18672 0.09014 0.00151  0.00717  0.01306  1264 LYS A CD  
2317 C CE  A LYS A 258 ? 0.37141 0.19705 0.13866 0.02888  0.02270  0.06605  1264 LYS A CE  
2318 C CE  B LYS A 258 ? 0.22498 0.19044 0.09248 0.01219  0.00661  0.00981  1264 LYS A CE  
2319 N NZ  A LYS A 258 ? 0.38790 0.22570 0.15093 0.04599  0.02087  0.06791  1264 LYS A NZ  
2320 N NZ  B LYS A 258 ? 0.22083 0.19889 0.09391 0.01732  0.00566  0.01040  1264 LYS A NZ  
2321 N N   . LEU A 259 ? 0.20632 0.16282 0.07125 -0.03676 -0.00788 0.01988  1265 LEU A N   
2322 C CA  . LEU A 259 ? 0.20525 0.15475 0.07475 -0.01698 -0.00825 0.00558  1265 LEU A CA  
2323 C C   . LEU A 259 ? 0.19066 0.15783 0.07321 -0.01823 0.00083  0.01696  1265 LEU A C   
2324 O O   . LEU A 259 ? 0.18680 0.15868 0.07981 -0.02756 -0.00458 0.00790  1265 LEU A O   
2325 C CB  . LEU A 259 ? 0.21572 0.14287 0.08307 -0.03858 -0.01325 0.00359  1265 LEU A CB  
2326 C CG  . LEU A 259 ? 0.21630 0.15973 0.09312 -0.02549 -0.01373 0.00628  1265 LEU A CG  
2327 C CD1 . LEU A 259 ? 0.22265 0.17343 0.09319 -0.00203 -0.02118 -0.00514 1265 LEU A CD1 
2328 C CD2 . LEU A 259 ? 0.21277 0.18262 0.09952 -0.03618 -0.00970 -0.00059 1265 LEU A CD2 
2329 N N   . LEU A 260 ? 0.18488 0.16800 0.07517 -0.03851 -0.00761 0.00463  1266 LEU A N   
2330 C CA  . LEU A 260 ? 0.19393 0.14609 0.08109 -0.03443 -0.00653 0.00526  1266 LEU A CA  
2331 C C   . LEU A 260 ? 0.20112 0.14286 0.08063 -0.03527 -0.00758 0.00685  1266 LEU A C   
2332 O O   . LEU A 260 ? 0.19061 0.16840 0.08463 -0.02455 -0.00632 0.01677  1266 LEU A O   
2333 C CB  . LEU A 260 ? 0.17887 0.18513 0.09134 -0.03104 -0.00477 0.01497  1266 LEU A CB  
2334 C CG  . LEU A 260 ? 0.18931 0.18666 0.10129 -0.03017 -0.00351 0.01387  1266 LEU A CG  
2335 C CD1 . LEU A 260 ? 0.19706 0.21554 0.11319 -0.03017 -0.00273 0.01404  1266 LEU A CD1 
2336 C CD2 . LEU A 260 ? 0.20148 0.18562 0.10063 -0.03539 0.00157  0.00949  1266 LEU A CD2 
2337 N N   . ASP A 261 ? 0.21982 0.15656 0.08087 -0.03063 0.00754  0.01878  1267 ASP A N   
2338 C CA  . ASP A 261 ? 0.22430 0.17872 0.08546 -0.01456 0.00833  0.01492  1267 ASP A CA  
2339 C C   . ASP A 261 ? 0.21831 0.17631 0.08869 -0.02811 0.01152  0.00554  1267 ASP A C   
2340 O O   . ASP A 261 ? 0.26304 0.21011 0.10276 0.00510  0.00476  -0.01693 1267 ASP A O   
2341 C CB  . ASP A 261 ? 0.23450 0.20022 0.08800 -0.03006 -0.00373 0.02110  1267 ASP A CB  
2342 C CG  . ASP A 261 ? 0.26287 0.21135 0.09381 -0.02204 -0.00966 0.02674  1267 ASP A CG  
2343 O OD1 . ASP A 261 ? 0.27191 0.23362 0.10384 -0.01993 -0.02219 0.01617  1267 ASP A OD1 
2344 O OD2 . ASP A 261 ? 0.29642 0.24300 0.09777 -0.01585 -0.01953 0.03696  1267 ASP A OD2 
2345 N N   . GLY A 262 ? 0.20399 0.18403 0.09361 -0.03856 0.00904  0.01002  1268 GLY A N   
2346 C CA  . GLY A 262 ? 0.20835 0.19602 0.10006 -0.02650 0.01166  0.01511  1268 GLY A CA  
2347 C C   . GLY A 262 ? 0.18846 0.19769 0.09828 -0.03341 0.00985  0.00958  1268 GLY A C   
2348 O O   . GLY A 262 ? 0.19496 0.23307 0.11457 -0.02689 0.00566  0.02173  1268 GLY A O   
2349 N N   . GLY A 263 ? 0.18948 0.16586 0.09166 -0.02854 0.01878  0.00387  1269 GLY A N   
2350 C CA  . GLY A 263 ? 0.17761 0.17955 0.08640 -0.01179 0.01077  0.00256  1269 GLY A CA  
2351 C C   . GLY A 263 ? 0.16449 0.16127 0.08498 -0.01783 -0.00080 -0.00387 1269 GLY A C   
2352 O O   . GLY A 263 ? 0.17580 0.15749 0.09176 -0.01102 -0.00009 0.00323  1269 GLY A O   
2353 N N   . ALA A 264 ? 0.15203 0.16983 0.08022 -0.03196 -0.00048 -0.00141 1270 ALA A N   
2354 C CA  . ALA A 264 ? 0.15250 0.15754 0.07689 -0.02299 -0.00321 0.01474  1270 ALA A CA  
2355 C C   . ALA A 264 ? 0.14359 0.15159 0.07280 -0.02914 -0.00492 0.00646  1270 ALA A C   
2356 O O   . ALA A 264 ? 0.16191 0.16329 0.07810 -0.03144 -0.00938 0.00520  1270 ALA A O   
2357 C CB  . ALA A 264 ? 0.17975 0.17189 0.08248 -0.01348 -0.01444 0.01048  1270 ALA A CB  
2358 N N   . HIS A 265 ? 0.12986 0.15701 0.06588 -0.01315 -0.00097 0.00109  1271 HIS A N   
2359 C CA  . HIS A 265 ? 0.12451 0.15241 0.07634 -0.01703 -0.00764 0.00506  1271 HIS A CA  
2360 C C   . HIS A 265 ? 0.12257 0.15109 0.07631 -0.01957 -0.00685 0.00575  1271 HIS A C   
2361 O O   . HIS A 265 ? 0.13915 0.15245 0.08255 -0.01326 -0.00367 -0.00809 1271 HIS A O   
2362 C CB  . HIS A 265 ? 0.13694 0.15867 0.07607 -0.02072 -0.00215 0.00069  1271 HIS A CB  
2363 C CG  . HIS A 265 ? 0.15084 0.15880 0.07825 -0.01527 -0.00001 -0.00132 1271 HIS A CG  
2364 N ND1 . HIS A 265 ? 0.15444 0.17224 0.08674 -0.02014 0.00449  0.00204  1271 HIS A ND1 
2365 C CD2 . HIS A 265 ? 0.14997 0.18821 0.08434 -0.00837 0.00645  0.00254  1271 HIS A CD2 
2366 C CE1 . HIS A 265 ? 0.14575 0.20268 0.09442 0.00034  0.00263  0.00344  1271 HIS A CE1 
2367 N NE2 . HIS A 265 ? 0.15661 0.19458 0.08861 0.00378  -0.00353 -0.00495 1271 HIS A NE2 
2368 N N   . ILE A 266 ? 0.13048 0.15465 0.07062 -0.01372 0.00289  0.00153  1272 ILE A N   
2369 C CA  . ILE A 266 ? 0.13370 0.15749 0.07184 -0.01391 -0.00877 0.00786  1272 ILE A CA  
2370 C C   . ILE A 266 ? 0.13409 0.14601 0.06523 -0.01105 -0.01478 0.00191  1272 ILE A C   
2371 O O   . ILE A 266 ? 0.14742 0.16825 0.06780 -0.01920 0.00322  0.00721  1272 ILE A O   
2372 C CB  . ILE A 266 ? 0.14448 0.17290 0.07246 -0.00747 -0.00945 0.01205  1272 ILE A CB  
2373 C CG1 . ILE A 266 ? 0.15092 0.16834 0.08360 0.00000  -0.01822 0.00672  1272 ILE A CG1 
2374 C CG2 . ILE A 266 ? 0.15161 0.18997 0.06956 -0.01724 -0.01561 0.01232  1272 ILE A CG2 
2375 C CD1 . ILE A 266 ? 0.17655 0.19306 0.08941 0.00840  -0.03049 0.00357  1272 ILE A CD1 
2376 N N   . TYR A 267 ? 0.13050 0.16013 0.06184 -0.00421 -0.00842 0.00523  1273 TYR A N   
2377 C CA  . TYR A 267 ? 0.12343 0.17974 0.06830 -0.01051 0.00169  0.01666  1273 TYR A CA  
2378 C C   . TYR A 267 ? 0.13395 0.17714 0.07027 -0.01604 -0.00649 0.00332  1273 TYR A C   
2379 O O   . TYR A 267 ? 0.12881 0.18996 0.07970 -0.01381 -0.00528 0.00585  1273 TYR A O   
2380 C CB  . TYR A 267 ? 0.11498 0.18570 0.06798 -0.00481 -0.01473 0.00815  1273 TYR A CB  
2381 C CG  . TYR A 267 ? 0.12319 0.15969 0.07290 -0.01042 -0.01713 0.00784  1273 TYR A CG  
2382 C CD1 . TYR A 267 ? 0.13073 0.16195 0.06975 -0.00730 -0.01359 0.00189  1273 TYR A CD1 
2383 C CD2 . TYR A 267 ? 0.13020 0.16392 0.07175 -0.01094 -0.01730 0.00653  1273 TYR A CD2 
2384 C CE1 . TYR A 267 ? 0.12715 0.15510 0.07333 -0.01683 -0.01500 0.00603  1273 TYR A CE1 
2385 C CE2 . TYR A 267 ? 0.13982 0.14985 0.07906 -0.01603 -0.01063 0.01124  1273 TYR A CE2 
2386 C CZ  . TYR A 267 ? 0.13216 0.15311 0.08602 -0.01261 -0.01534 0.01061  1273 TYR A CZ  
2387 O OH  . TYR A 267 ? 0.12842 0.16235 0.09310 -0.00995 -0.01042 0.00794  1273 TYR A OH  
2388 N N   . PHE A 268 ? 0.12161 0.19390 0.06752 -0.01715 -0.00225 0.01833  1274 PHE A N   
2389 C CA  . PHE A 268 ? 0.11274 0.22524 0.07176 -0.01687 -0.01298 0.00759  1274 PHE A CA  
2390 C C   . PHE A 268 ? 0.12271 0.22060 0.07661 -0.01290 -0.00720 0.00676  1274 PHE A C   
2391 O O   . PHE A 268 ? 0.13880 0.22105 0.07963 -0.02267 -0.00635 0.01412  1274 PHE A O   
2392 C CB  . PHE A 268 ? 0.12192 0.24171 0.07175 -0.01462 -0.01132 0.01567  1274 PHE A CB  
2393 C CG  . PHE A 268 ? 0.12318 0.22575 0.07812 -0.02292 -0.01681 0.00762  1274 PHE A CG  
2394 C CD1 . PHE A 268 ? 0.12967 0.23196 0.07650 -0.02932 -0.01328 0.00113  1274 PHE A CD1 
2395 C CD2 . PHE A 268 ? 0.13976 0.22741 0.07903 -0.00523 -0.02509 0.00485  1274 PHE A CD2 
2396 C CE1 . PHE A 268 ? 0.13597 0.24436 0.07786 -0.01777 -0.00754 0.00743  1274 PHE A CE1 
2397 C CE2 . PHE A 268 ? 0.13870 0.22635 0.07582 -0.01077 -0.02789 0.01073  1274 PHE A CE2 
2398 C CZ  . PHE A 268 ? 0.14079 0.23889 0.07674 -0.01134 -0.01547 0.01710  1274 PHE A CZ  
2399 N N   . CYS A 269 ? 0.11686 0.21618 0.06978 -0.00280 -0.01160 0.00819  1275 CYS A N   
2400 C CA  . CYS A 269 ? 0.12152 0.21649 0.06598 -0.01618 -0.00760 0.01924  1275 CYS A CA  
2401 C C   . CYS A 269 ? 0.11838 0.23752 0.06840 -0.00175 -0.01006 0.01956  1275 CYS A C   
2402 O O   . CYS A 269 ? 0.11868 0.23780 0.07167 0.00709  -0.00549 0.02351  1275 CYS A O   
2403 C CB  . CYS A 269 ? 0.12028 0.22357 0.06926 -0.00112 -0.02272 0.01675  1275 CYS A CB  
2404 S SG  . CYS A 269 ? 0.11608 0.24238 0.07587 -0.01204 -0.01322 0.02496  1275 CYS A SG  
2405 N N   . GLY A 270 ? 0.10734 0.27146 0.07685 -0.00741 -0.01304 0.02004  1276 GLY A N   
2406 C CA  . GLY A 270 ? 0.11782 0.30380 0.08247 0.00536  -0.00549 0.02035  1276 GLY A CA  
2407 C C   . GLY A 270 ? 0.10766 0.31857 0.08714 0.00500  -0.00743 0.02980  1276 GLY A C   
2408 O O   . GLY A 270 ? 0.12086 0.31524 0.08698 -0.00845 -0.00958 0.03036  1276 GLY A O   
2409 N N   . LEU A 271 ? 0.11937 0.35071 0.09932 0.01462  -0.01551 0.01978  1277 LEU A N   
2410 C CA  . LEU A 271 ? 0.11812 0.41321 0.11474 0.00342  -0.01128 0.02033  1277 LEU A CA  
2411 C C   . LEU A 271 ? 0.12498 0.42329 0.11675 -0.01107 -0.01278 0.02505  1277 LEU A C   
2412 O O   . LEU A 271 ? 0.13418 0.41207 0.12145 -0.00666 -0.02243 0.02240  1277 LEU A O   
2413 C CB  . LEU A 271 ? 0.14913 0.44306 0.12399 0.02698  -0.01598 0.02598  1277 LEU A CB  
2414 C CG  . LEU A 271 ? 0.16538 0.44734 0.13488 0.01090  0.00640  0.03435  1277 LEU A CG  
2415 C CD1 . LEU A 271 ? 0.22139 0.47708 0.14605 0.08185  0.02776  0.04768  1277 LEU A CD1 
2416 C CD2 . LEU A 271 ? 0.17181 0.44077 0.12759 0.00773  0.00646  0.03208  1277 LEU A CD2 
2417 N N   . LYS A 272 ? 0.13181 0.43201 0.11334 -0.02119 -0.00897 0.02238  1278 LYS A N   
2418 C CA  . LYS A 272 ? 0.17129 0.46926 0.12716 -0.02357 -0.02175 0.01056  1278 LYS A CA  
2419 C C   . LYS A 272 ? 0.13743 0.47993 0.12619 -0.02130 -0.00933 0.01655  1278 LYS A C   
2420 O O   . LYS A 272 ? 0.14508 0.49419 0.13154 -0.02155 -0.01220 0.01289  1278 LYS A O   
2421 C CB  . LYS A 272 ? 0.23431 0.52304 0.14078 -0.03094 -0.02986 0.00258  1278 LYS A CB  
2422 C CG  . LYS A 272 ? 0.33696 0.57049 0.15815 0.01804  -0.03722 -0.00890 1278 LYS A CG  
2423 C CD  . LYS A 272 ? 0.45548 0.61439 0.17469 0.08637  -0.04036 -0.02103 1278 LYS A CD  
2424 C CE  . LYS A 272 ? 0.54015 0.65405 0.19096 0.12700  -0.04062 -0.02795 1278 LYS A CE  
2425 N NZ  . LYS A 272 ? 0.59256 0.68077 0.20508 0.15809  -0.03679 -0.02595 1278 LYS A NZ  
2426 N N   . GLY A 273 ? 0.13905 0.47705 0.12887 -0.00369 -0.01229 0.02131  1279 GLY A N   
2427 C CA  . GLY A 273 ? 0.15120 0.47767 0.12791 0.01243  -0.01109 0.03005  1279 GLY A CA  
2428 C C   . GLY A 273 ? 0.15813 0.47333 0.13092 0.03759  -0.00991 0.03864  1279 GLY A C   
2429 O O   . GLY A 273 ? 0.15495 0.49070 0.13775 0.02805  -0.00884 0.04951  1279 GLY A O   
2430 N N   . MET A 274 ? 0.15726 0.44870 0.12344 0.03731  -0.00925 0.03709  1280 MET A N   
2431 C CA  . MET A 274 ? 0.17115 0.41862 0.11527 0.04473  -0.00924 0.03476  1280 MET A CA  
2432 C C   . MET A 274 ? 0.17074 0.42329 0.11953 0.05620  -0.01189 0.03287  1280 MET A C   
2433 O O   . MET A 274 ? 0.16819 0.42210 0.12047 0.02975  -0.01425 0.04447  1280 MET A O   
2434 C CB  . MET A 274 ? 0.15934 0.40531 0.11292 0.04444  -0.01323 0.02787  1280 MET A CB  
2435 C CG  . MET A 274 ? 0.14383 0.38032 0.10054 0.01943  -0.00414 0.02977  1280 MET A CG  
2436 S SD  . MET A 274 ? 0.13492 0.33257 0.09397 0.01472  -0.01379 0.03224  1280 MET A SD  
2437 C CE  . MET A 274 ? 0.15006 0.30847 0.08782 0.02147  -0.01402 0.02676  1280 MET A CE  
2438 N N   . MET A 275 ? 0.15442 0.43101 0.11919 0.02797  -0.01533 0.02797  1281 MET A N   
2439 C CA  . MET A 275 ? 0.13741 0.41709 0.11695 -0.00982 -0.01623 0.03484  1281 MET A CA  
2440 C C   . MET A 275 ? 0.14892 0.42894 0.12193 -0.01489 -0.01818 0.04330  1281 MET A C   
2441 O O   . MET A 275 ? 0.14289 0.44542 0.12375 -0.02110 -0.00938 0.05224  1281 MET A O   
2442 C CB  . MET A 275 ? 0.15779 0.38065 0.11129 -0.02927 -0.02708 0.03294  1281 MET A CB  
2443 C CG  . MET A 275 ? 0.15809 0.37570 0.10447 -0.01214 -0.02358 0.01972  1281 MET A CG  
2444 S SD  . MET A 275 ? 0.14465 0.33511 0.09560 -0.00299 -0.02631 0.00248  1281 MET A SD  
2445 C CE  . MET A 275 ? 0.15408 0.34391 0.09310 -0.01334 -0.01849 -0.00845 1281 MET A CE  
2446 N N   . PRO A 276 ? 0.15075 0.45380 0.13339 -0.01288 -0.02253 0.04291  1282 PRO A N   
2447 C CA  . PRO A 276 ? 0.16170 0.47568 0.14035 -0.00237 -0.02621 0.03665  1282 PRO A CA  
2448 C C   . PRO A 276 ? 0.16739 0.48705 0.13822 0.02327  -0.01460 0.04880  1282 PRO A C   
2449 O O   . PRO A 276 ? 0.17350 0.49537 0.14119 0.02973  -0.01273 0.05380  1282 PRO A O   
2450 C CB  . PRO A 276 ? 0.16161 0.48741 0.14292 0.00021  -0.02666 0.02645  1282 PRO A CB  
2451 C CG  . PRO A 276 ? 0.17376 0.48428 0.13984 0.00424  -0.02748 0.03117  1282 PRO A CG  
2452 C CD  . PRO A 276 ? 0.15336 0.46742 0.13324 -0.03493 -0.01764 0.05201  1282 PRO A CD  
2453 N N   . GLY A 277 ? 0.18254 0.48358 0.14058 0.05022  -0.01639 0.04574  1283 GLY A N   
2454 C CA  . GLY A 277 ? 0.19163 0.46921 0.13967 0.06810  -0.00979 0.05438  1283 GLY A CA  
2455 C C   . GLY A 277 ? 0.19210 0.44941 0.13434 0.06281  -0.01419 0.04985  1283 GLY A C   
2456 O O   . GLY A 277 ? 0.22258 0.45311 0.13727 0.08070  -0.01135 0.05293  1283 GLY A O   
2457 N N   . ILE A 278 ? 0.19206 0.43566 0.13317 0.05413  -0.01385 0.05826  1284 ILE A N   
2458 C CA  . ILE A 278 ? 0.17683 0.41595 0.12675 0.04801  -0.01203 0.05678  1284 ILE A CA  
2459 C C   . ILE A 278 ? 0.18232 0.41588 0.12556 0.04219  -0.01066 0.05948  1284 ILE A C   
2460 O O   . ILE A 278 ? 0.18437 0.41090 0.12802 0.04547  -0.00613 0.06801  1284 ILE A O   
2461 C CB  . ILE A 278 ? 0.17051 0.40305 0.12384 0.04240  -0.01140 0.05867  1284 ILE A CB  
2462 C CG1 . ILE A 278 ? 0.17089 0.41763 0.12381 0.04011  -0.00511 0.06017  1284 ILE A CG1 
2463 C CG2 . ILE A 278 ? 0.17230 0.38738 0.12105 0.04952  -0.00490 0.06276  1284 ILE A CG2 
2464 C CD1 . ILE A 278 ? 0.16468 0.42152 0.12345 0.04067  -0.00931 0.05262  1284 ILE A CD1 
2465 N N   . GLN A 279 ? 0.18736 0.42241 0.12602 0.05369  -0.01044 0.05389  1285 GLN A N   
2466 C CA  . GLN A 279 ? 0.19458 0.40041 0.12014 0.03368  -0.01050 0.05977  1285 GLN A CA  
2467 C C   . GLN A 279 ? 0.19027 0.39576 0.12066 0.03185  -0.00980 0.06309  1285 GLN A C   
2468 O O   . GLN A 279 ? 0.18938 0.39061 0.12066 0.02084  0.00141  0.07116  1285 GLN A O   
2469 C CB  . GLN A 279 ? 0.19135 0.38975 0.13053 0.01989  -0.00541 0.06551  1285 GLN A CB  
2470 C CG  . GLN A 279 ? 0.18388 0.37030 0.14012 0.00457  0.01056  0.06995  1285 GLN A CG  
2471 C CD  . GLN A 279 ? 0.19077 0.33514 0.14468 -0.01337 0.00320  0.04895  1285 GLN A CD  
2472 O OE1 . GLN A 279 ? 0.20993 0.36186 0.15020 -0.01422 0.02018  0.06336  1285 GLN A OE1 
2473 N NE2 . GLN A 279 ? 0.20622 0.33060 0.14967 0.01504  -0.01743 0.02854  1285 GLN A NE2 
2474 N N   . ASP A 280 ? 0.20305 0.41209 0.12873 0.04889  -0.02345 0.05275  1286 ASP A N   
2475 C CA  A ASP A 280 ? 0.21432 0.42125 0.13368 0.06868  -0.02394 0.04866  1286 ASP A CA  
2476 C CA  B ASP A 280 ? 0.21543 0.40656 0.12627 0.06146  -0.02319 0.04653  1286 ASP A CA  
2477 C C   . ASP A 280 ? 0.22942 0.41272 0.12851 0.08135  -0.01735 0.04560  1286 ASP A C   
2478 O O   . ASP A 280 ? 0.25459 0.41357 0.12816 0.08719  -0.00983 0.04976  1286 ASP A O   
2479 C CB  A ASP A 280 ? 0.23173 0.44677 0.14349 0.07669  -0.02525 0.05343  1286 ASP A CB  
2480 C CB  B ASP A 280 ? 0.22637 0.41245 0.12537 0.04758  -0.02485 0.04938  1286 ASP A CB  
2481 C CG  A ASP A 280 ? 0.26964 0.47218 0.15377 0.09107  -0.02634 0.05891  1286 ASP A CG  
2482 C CG  B ASP A 280 ? 0.24232 0.42167 0.12307 0.04299  -0.02240 0.04665  1286 ASP A CG  
2483 O OD1 A ASP A 280 ? 0.28905 0.49891 0.16406 0.09949  -0.03230 0.05816  1286 ASP A OD1 
2484 O OD1 B ASP A 280 ? 0.25996 0.42174 0.12078 0.04536  -0.02358 0.04008  1286 ASP A OD1 
2485 O OD2 A ASP A 280 ? 0.29206 0.48000 0.15877 0.10938  -0.02045 0.06220  1286 ASP A OD2 
2486 O OD2 B ASP A 280 ? 0.24814 0.44589 0.12658 0.04215  -0.01876 0.04638  1286 ASP A OD2 
2487 N N   . THR A 281 ? 0.24833 0.41015 0.12035 0.08608  -0.01169 0.03278  1287 THR A N   
2488 C CA  . THR A 281 ? 0.27106 0.37591 0.11783 0.11234  -0.00431 0.02772  1287 THR A CA  
2489 C C   . THR A 281 ? 0.26414 0.33306 0.10894 0.08746  -0.00494 0.03955  1287 THR A C   
2490 O O   . THR A 281 ? 0.29063 0.31925 0.10818 0.08039  0.00873  0.04544  1287 THR A O   
2491 C CB  . THR A 281 ? 0.30289 0.38460 0.12127 0.11687  0.00785  0.02944  1287 THR A CB  
2492 O OG1 . THR A 281 ? 0.31784 0.41666 0.13356 0.14207  0.00934  0.02932  1287 THR A OG1 
2493 C CG2 . THR A 281 ? 0.30761 0.37930 0.12245 0.12017  0.00387  0.03059  1287 THR A CG2 
2494 N N   . LEU A 282 ? 0.22075 0.32692 0.10378 0.05801  -0.00234 0.05004  1288 LEU A N   
2495 C CA  . LEU A 282 ? 0.21149 0.30690 0.10400 0.04377  -0.00752 0.04912  1288 LEU A CA  
2496 C C   . LEU A 282 ? 0.21988 0.30197 0.10484 0.03232  -0.00644 0.05339  1288 LEU A C   
2497 O O   . LEU A 282 ? 0.23530 0.28908 0.10800 0.02208  0.00444  0.05072  1288 LEU A O   
2498 C CB  . LEU A 282 ? 0.19030 0.28173 0.10781 0.03082  -0.00715 0.04523  1288 LEU A CB  
2499 C CG  . LEU A 282 ? 0.19479 0.27675 0.11540 0.02739  -0.01084 0.04019  1288 LEU A CG  
2500 C CD1 . LEU A 282 ? 0.20301 0.28278 0.11417 0.05235  -0.00111 0.04778  1288 LEU A CD1 
2501 C CD2 . LEU A 282 ? 0.21388 0.29679 0.12954 0.01587  -0.01365 0.02782  1288 LEU A CD2 
2502 N N   . LYS A 283 ? 0.23401 0.31344 0.11225 0.04089  -0.01840 0.05623  1289 LYS A N   
2503 C CA  . LYS A 283 ? 0.25367 0.32800 0.12826 0.03104  -0.03341 0.05489  1289 LYS A CA  
2504 C C   . LYS A 283 ? 0.24796 0.31316 0.13316 0.03310  -0.02646 0.06551  1289 LYS A C   
2505 O O   . LYS A 283 ? 0.25152 0.30211 0.12402 -0.00312 -0.01232 0.06760  1289 LYS A O   
2506 C CB  . LYS A 283 ? 0.28587 0.39413 0.14347 -0.01032 -0.04227 0.05186  1289 LYS A CB  
2507 C CG  . LYS A 283 ? 0.36786 0.48332 0.16532 0.03063  -0.04650 0.04007  1289 LYS A CG  
2508 C CD  . LYS A 283 ? 0.43173 0.56249 0.18388 0.05890  -0.05005 0.02986  1289 LYS A CD  
2509 C CE  . LYS A 283 ? 0.48629 0.62549 0.19706 0.10394  -0.05193 0.02478  1289 LYS A CE  
2510 N NZ  . LYS A 283 ? 0.51650 0.67045 0.20353 0.12155  -0.05337 0.02261  1289 LYS A NZ  
2511 N N   . LYS A 284 ? 0.24007 0.30424 0.15276 0.04160  -0.03311 0.06501  1290 LYS A N   
2512 C CA  . LYS A 284 ? 0.26726 0.29262 0.17917 0.06027  -0.03100 0.06025  1290 LYS A CA  
2513 C C   . LYS A 284 ? 0.29519 0.27502 0.13936 0.06235  -0.03209 0.04085  1290 LYS A C   
2514 O O   . LYS A 284 ? 0.33805 0.28316 0.13370 0.05858  -0.01218 0.05909  1290 LYS A O   
2520 N N   . VAL A 285 ? 0.28553 0.26826 0.11753 0.04422  -0.03373 0.01648  1291 VAL A N   
2521 C CA  . VAL A 285 ? 0.29336 0.26399 0.11138 0.03415  -0.02848 0.00403  1291 VAL A CA  
2522 C C   . VAL A 285 ? 0.27609 0.22511 0.10976 0.00202  -0.01999 0.00596  1291 VAL A C   
2523 O O   . VAL A 285 ? 0.28337 0.21634 0.11450 -0.01164 -0.00677 0.01254  1291 VAL A O   
2524 C CB  . VAL A 285 ? 0.32351 0.30263 0.11384 0.01783  -0.03154 -0.00672 1291 VAL A CB  
2525 C CG1 . VAL A 285 ? 0.35045 0.31422 0.12001 0.03297  -0.02750 0.00847  1291 VAL A CG1 
2526 C CG2 . VAL A 285 ? 0.35286 0.34149 0.11276 0.03938  -0.02978 -0.01828 1291 VAL A CG2 
2527 N N   . ALA A 286 ? 0.24042 0.21868 0.10505 -0.00637 -0.01999 0.01690  1292 ALA A N   
2528 C CA  . ALA A 286 ? 0.24816 0.20280 0.10961 -0.00365 -0.01321 0.02745  1292 ALA A CA  
2529 C C   . ALA A 286 ? 0.26173 0.19374 0.10298 -0.02860 -0.01479 0.01328  1292 ALA A C   
2530 O O   . ALA A 286 ? 0.25373 0.19831 0.10526 -0.04138 0.00805  0.02325  1292 ALA A O   
2531 C CB  . ALA A 286 ? 0.25204 0.17528 0.12092 -0.00736 -0.01446 0.02974  1292 ALA A CB  
2532 N N   . GLU A 287 ? 0.26626 0.23672 0.10230 -0.03046 -0.03662 0.02135  1293 GLU A N   
2533 C CA  A GLU A 287 ? 0.28490 0.25159 0.10902 -0.03644 -0.03786 0.03005  1293 GLU A CA  
2534 C CA  B GLU A 287 ? 0.27689 0.25681 0.10715 -0.04877 -0.03906 0.03901  1293 GLU A CA  
2535 C C   . GLU A 287 ? 0.28426 0.24633 0.10837 -0.03508 -0.03572 0.03427  1293 GLU A C   
2536 O O   . GLU A 287 ? 0.28459 0.23985 0.10367 -0.02976 -0.02796 0.04451  1293 GLU A O   
2537 C CB  A GLU A 287 ? 0.30946 0.30290 0.12075 -0.03125 -0.04334 0.02879  1293 GLU A CB  
2538 C CB  B GLU A 287 ? 0.28737 0.33611 0.11794 -0.06422 -0.04750 0.04903  1293 GLU A CB  
2539 C CG  A GLU A 287 ? 0.35381 0.35948 0.13404 -0.00327 -0.03896 0.01831  1293 GLU A CG  
2540 C CG  B GLU A 287 ? 0.33208 0.44356 0.13174 -0.02697 -0.04232 0.04474  1293 GLU A CG  
2541 C CD  A GLU A 287 ? 0.39093 0.39657 0.14660 0.00770  -0.03517 0.00703  1293 GLU A CD  
2542 C CD  B GLU A 287 ? 0.37744 0.54287 0.14531 -0.00680 -0.03134 0.04097  1293 GLU A CD  
2543 O OE1 A GLU A 287 ? 0.40104 0.41384 0.15013 0.00679  -0.03543 0.00472  1293 GLU A OE1 
2544 O OE1 B GLU A 287 ? 0.38526 0.57261 0.15129 -0.01277 -0.03320 0.03285  1293 GLU A OE1 
2545 O OE2 A GLU A 287 ? 0.40392 0.40857 0.15310 0.00897  -0.03264 0.00892  1293 GLU A OE2 
2546 O OE2 B GLU A 287 ? 0.39474 0.58344 0.15410 0.00908  -0.02503 0.04221  1293 GLU A OE2 
2547 N N   . ARG A 288 ? 0.30520 0.22397 0.11704 -0.02211 -0.03034 0.04162  1294 ARG A N   
2548 C CA  . ARG A 288 ? 0.32168 0.21158 0.13131 -0.02016 -0.02029 0.03895  1294 ARG A CA  
2549 C C   . ARG A 288 ? 0.30842 0.17796 0.13487 -0.04650 -0.03433 0.02769  1294 ARG A C   
2550 O O   . ARG A 288 ? 0.33225 0.20231 0.14259 -0.03648 -0.02517 0.03754  1294 ARG A O   
2551 C CB  . ARG A 288 ? 0.38026 0.27758 0.14981 0.01251  0.00622  0.04301  1294 ARG A CB  
2552 C CG  . ARG A 288 ? 0.44465 0.39839 0.16745 0.04352  0.01564  0.05351  1294 ARG A CG  
2553 C CD  . ARG A 288 ? 0.50268 0.52065 0.18176 0.07728  0.02297  0.05865  1294 ARG A CD  
2554 N NE  . ARG A 288 ? 0.55894 0.61879 0.19343 0.11835  0.02729  0.05644  1294 ARG A NE  
2555 C CZ  . ARG A 288 ? 0.59273 0.69365 0.20534 0.13305  0.03195  0.05489  1294 ARG A CZ  
2556 N NH1 . ARG A 288 ? 0.60688 0.70555 0.20665 0.13448  0.02662  0.04846  1294 ARG A NH1 
2557 N NH2 . ARG A 288 ? 0.60663 0.73114 0.21656 0.15270  0.03550  0.05106  1294 ARG A NH2 
2558 N N   . ARG A 289 ? 0.30358 0.18560 0.13348 -0.02091 -0.02806 0.02729  1295 ARG A N   
2559 C CA  . ARG A 289 ? 0.30163 0.20402 0.13355 -0.02709 -0.02376 0.02385  1295 ARG A CA  
2560 C C   . ARG A 289 ? 0.29105 0.20457 0.12936 -0.04960 -0.00605 0.03640  1295 ARG A C   
2561 O O   . ARG A 289 ? 0.27336 0.25003 0.13725 -0.05409 0.00140  0.03810  1295 ARG A O   
2562 C CB  . ARG A 289 ? 0.30274 0.20330 0.13760 -0.02946 -0.03143 0.02389  1295 ARG A CB  
2563 C CG  . ARG A 289 ? 0.31315 0.22667 0.13962 -0.01008 -0.03872 0.01365  1295 ARG A CG  
2564 C CD  . ARG A 289 ? 0.29750 0.26370 0.13598 -0.01738 -0.03426 0.01697  1295 ARG A CD  
2565 N NE  . ARG A 289 ? 0.29383 0.26652 0.13177 -0.03961 -0.03370 0.02500  1295 ARG A NE  
2566 C CZ  . ARG A 289 ? 0.29661 0.28329 0.12951 -0.05623 -0.02492 0.03655  1295 ARG A CZ  
2567 N NH1 . ARG A 289 ? 0.32109 0.26595 0.12764 -0.05786 -0.03150 0.01786  1295 ARG A NH1 
2568 N NH2 . ARG A 289 ? 0.29473 0.31323 0.13450 -0.05916 -0.01893 0.04965  1295 ARG A NH2 
2569 N N   . GLY A 290 ? 0.30511 0.17830 0.11969 -0.04730 0.00042  0.03297  1296 GLY A N   
2570 C CA  . GLY A 290 ? 0.31929 0.18071 0.11280 -0.03248 0.00426  0.02680  1296 GLY A CA  
2571 C C   . GLY A 290 ? 0.30187 0.19473 0.10920 -0.02696 0.00035  0.02155  1296 GLY A C   
2572 O O   . GLY A 290 ? 0.32393 0.21785 0.11712 -0.00075 0.01222  0.03239  1296 GLY A O   
2573 N N   . GLU A 291 ? 0.28238 0.20660 0.10793 -0.05710 -0.01700 0.03556  1297 GLU A N   
2574 C CA  A GLU A 291 ? 0.29049 0.22229 0.11538 -0.04560 -0.02420 0.02693  1297 GLU A CA  
2575 C CA  B GLU A 291 ? 0.26967 0.22111 0.11179 -0.06902 -0.02666 0.02747  1297 GLU A CA  
2576 C C   . GLU A 291 ? 0.27594 0.19638 0.11826 -0.06489 -0.03082 0.03364  1297 GLU A C   
2577 O O   . GLU A 291 ? 0.29931 0.23396 0.14280 -0.05655 -0.03455 0.01841  1297 GLU A O   
2578 C CB  A GLU A 291 ? 0.30695 0.23915 0.11923 -0.03782 -0.02269 0.01917  1297 GLU A CB  
2579 C CB  B GLU A 291 ? 0.24278 0.23256 0.10734 -0.10698 -0.03045 0.02266  1297 GLU A CB  
2580 C CG  A GLU A 291 ? 0.33662 0.25273 0.12635 -0.02477 -0.01967 0.01849  1297 GLU A CG  
2581 C CG  B GLU A 291 ? 0.24870 0.24540 0.10262 -0.09989 -0.02869 0.03062  1297 GLU A CG  
2582 C CD  A GLU A 291 ? 0.35076 0.27127 0.13084 -0.01872 -0.01677 0.03186  1297 GLU A CD  
2583 C CD  B GLU A 291 ? 0.27361 0.28698 0.10636 -0.07947 -0.02263 0.02720  1297 GLU A CD  
2584 O OE1 A GLU A 291 ? 0.36753 0.31987 0.13210 -0.00656 -0.02449 0.03849  1297 GLU A OE1 
2585 O OE1 B GLU A 291 ? 0.27527 0.28442 0.10682 -0.09140 -0.00970 0.04574  1297 GLU A OE1 
2586 O OE2 A GLU A 291 ? 0.35732 0.21540 0.12901 -0.02249 -0.01187 0.04795  1297 GLU A OE2 
2587 O OE2 B GLU A 291 ? 0.29722 0.34247 0.11386 -0.04008 -0.02469 0.00945  1297 GLU A OE2 
2588 N N   . SER A 292 ? 0.28208 0.20411 0.12179 -0.05359 -0.02303 0.04279  1298 SER A N   
2589 C CA  . SER A 292 ? 0.27307 0.20250 0.11741 -0.06656 -0.02837 0.04371  1298 SER A CA  
2590 C C   . SER A 292 ? 0.24657 0.18194 0.11270 -0.06224 -0.02037 0.03595  1298 SER A C   
2591 O O   . SER A 292 ? 0.23987 0.20089 0.10440 -0.03960 -0.01307 0.03002  1298 SER A O   
2592 C CB  . SER A 292 ? 0.30883 0.22309 0.12684 -0.05678 -0.02747 0.03413  1298 SER A CB  
2593 O OG  . SER A 292 ? 0.31819 0.22440 0.13390 -0.05398 -0.03304 0.03284  1298 SER A OG  
2594 N N   . TRP A 293 ? 0.24907 0.19324 0.12249 -0.04699 -0.01546 0.04294  1299 TRP A N   
2595 C CA  . TRP A 293 ? 0.23251 0.19250 0.12418 -0.03683 -0.01119 0.03635  1299 TRP A CA  
2596 C C   . TRP A 293 ? 0.21938 0.20222 0.12077 -0.03672 -0.01008 0.03811  1299 TRP A C   
2597 O O   . TRP A 293 ? 0.23489 0.21957 0.11689 -0.00360 -0.01447 0.02458  1299 TRP A O   
2598 C CB  . TRP A 293 ? 0.23576 0.20317 0.13169 -0.02575 0.00396  0.02220  1299 TRP A CB  
2599 C CG  . TRP A 293 ? 0.23782 0.21344 0.13573 -0.04020 0.02192  0.01112  1299 TRP A CG  
2600 C CD1 . TRP A 293 ? 0.25091 0.23248 0.14113 -0.04380 0.03431  0.01090  1299 TRP A CD1 
2601 C CD2 . TRP A 293 ? 0.25264 0.21717 0.12929 -0.04247 0.02424  0.00613  1299 TRP A CD2 
2602 N NE1 . TRP A 293 ? 0.28505 0.24087 0.13996 -0.04111 0.03291  0.00529  1299 TRP A NE1 
2603 C CE2 . TRP A 293 ? 0.28351 0.21863 0.12892 -0.02760 0.02369  0.00110  1299 TRP A CE2 
2604 C CE3 . TRP A 293 ? 0.25270 0.22855 0.12443 -0.03345 0.01654  -0.00404 1299 TRP A CE3 
2605 C CZ2 . TRP A 293 ? 0.30615 0.24215 0.12124 -0.00662 0.01434  0.00412  1299 TRP A CZ2 
2606 C CZ3 . TRP A 293 ? 0.27554 0.23754 0.12081 -0.01444 0.01325  -0.00226 1299 TRP A CZ3 
2607 C CH2 . TRP A 293 ? 0.29930 0.26738 0.12020 0.01021  0.00669  -0.00258 1299 TRP A CH2 
2608 N N   . ASP A 294 ? 0.23551 0.19784 0.13049 -0.04840 -0.01257 0.04331  1300 ASP A N   
2609 C CA  . ASP A 294 ? 0.24229 0.21019 0.14205 -0.05867 -0.01735 0.04880  1300 ASP A CA  
2610 C C   . ASP A 294 ? 0.24810 0.19721 0.12874 -0.05502 -0.02252 0.03229  1300 ASP A C   
2611 O O   . ASP A 294 ? 0.23819 0.18953 0.13215 -0.05341 -0.03742 0.02568  1300 ASP A O   
2612 C CB  . ASP A 294 ? 0.25532 0.23233 0.16617 -0.06627 -0.02842 0.04816  1300 ASP A CB  
2613 C CG  . ASP A 294 ? 0.28442 0.24118 0.18669 -0.06028 -0.03587 0.04965  1300 ASP A CG  
2614 O OD1 . ASP A 294 ? 0.27870 0.28239 0.19792 -0.07402 -0.01760 0.05761  1300 ASP A OD1 
2615 O OD2 . ASP A 294 ? 0.32950 0.26186 0.19801 -0.04212 -0.05708 0.01517  1300 ASP A OD2 
2616 N N   . GLN A 295 ? 0.24205 0.22662 0.11055 -0.04290 -0.02816 0.01724  1301 GLN A N   
2617 C CA  A GLN A 295 ? 0.25016 0.27445 0.10311 -0.04638 -0.01823 0.01286  1301 GLN A CA  
2618 C CA  B GLN A 295 ? 0.25543 0.25828 0.10501 -0.04319 -0.01766 0.01217  1301 GLN A CA  
2619 C C   . GLN A 295 ? 0.22589 0.24320 0.09691 -0.05968 -0.00494 0.01349  1301 GLN A C   
2620 O O   . GLN A 295 ? 0.22558 0.23768 0.09402 -0.04315 0.00258  0.01540  1301 GLN A O   
2621 C CB  A GLN A 295 ? 0.29179 0.35436 0.10624 -0.01831 -0.01991 0.01785  1301 GLN A CB  
2622 C CB  B GLN A 295 ? 0.30361 0.30830 0.11019 -0.01236 -0.01999 0.01164  1301 GLN A CB  
2623 C CG  A GLN A 295 ? 0.34033 0.39133 0.11774 -0.01519 -0.02492 0.01301  1301 GLN A CG  
2624 C CG  B GLN A 295 ? 0.35238 0.34175 0.12070 0.00307  -0.02287 0.01055  1301 GLN A CG  
2625 C CD  A GLN A 295 ? 0.38955 0.44536 0.13185 0.00265  -0.02394 0.00932  1301 GLN A CD  
2626 C CD  B GLN A 295 ? 0.40013 0.38260 0.13280 0.02679  -0.02325 0.00592  1301 GLN A CD  
2627 O OE1 A GLN A 295 ? 0.41341 0.47813 0.14169 0.00925  -0.00706 0.01544  1301 GLN A OE1 
2628 O OE1 B GLN A 295 ? 0.41572 0.38256 0.13950 0.02748  -0.02784 -0.00544 1301 GLN A OE1 
2629 N NE2 A GLN A 295 ? 0.40078 0.45323 0.13554 0.01015  -0.04091 0.00206  1301 GLN A NE2 
2630 N NE2 B GLN A 295 ? 0.41375 0.40597 0.13394 0.04019  -0.02183 0.00420  1301 GLN A NE2 
2631 N N   . LYS A 296 ? 0.22847 0.20533 0.09352 -0.06076 0.00228  0.02195  1302 LYS A N   
2632 C CA  A LYS A 296 ? 0.22948 0.19083 0.10117 -0.05967 -0.00050 0.00880  1302 LYS A CA  
2633 C CA  B LYS A 296 ? 0.22337 0.19334 0.09791 -0.05889 -0.00261 0.01602  1302 LYS A CA  
2634 C C   . LYS A 296 ? 0.20072 0.18048 0.09353 -0.06875 -0.00488 0.00706  1302 LYS A C   
2635 O O   . LYS A 296 ? 0.19692 0.19351 0.10365 -0.06031 -0.00639 0.00976  1302 LYS A O   
2636 C CB  A LYS A 296 ? 0.25164 0.18667 0.11640 -0.06786 0.00105  0.00388  1302 LYS A CB  
2637 C CB  B LYS A 296 ? 0.23695 0.18398 0.10607 -0.06313 -0.00661 0.02094  1302 LYS A CB  
2638 C CG  A LYS A 296 ? 0.25845 0.20668 0.12670 -0.06673 -0.00543 -0.01467 1302 LYS A CG  
2639 C CG  B LYS A 296 ? 0.22849 0.20059 0.10899 -0.05525 -0.01685 0.00971  1302 LYS A CG  
2640 C CD  A LYS A 296 ? 0.26837 0.23476 0.13074 -0.07510 -0.00080 -0.01716 1302 LYS A CD  
2641 C CD  B LYS A 296 ? 0.22204 0.22274 0.11605 -0.06564 -0.01568 0.00688  1302 LYS A CD  
2642 C CE  A LYS A 296 ? 0.27676 0.24436 0.13065 -0.07619 0.00134  -0.01997 1302 LYS A CE  
2643 C CE  B LYS A 296 ? 0.22471 0.23430 0.11871 -0.06432 -0.01484 -0.00124 1302 LYS A CE  
2644 N NZ  A LYS A 296 ? 0.28816 0.25090 0.12896 -0.05704 0.00066  -0.02019 1302 LYS A NZ  
2645 N NZ  B LYS A 296 ? 0.20243 0.23668 0.12001 -0.08604 -0.01860 -0.00418 1302 LYS A NZ  
2646 N N   . LEU A 297 ? 0.18750 0.18447 0.08702 -0.06555 0.00059  0.01337  1303 LEU A N   
2647 C CA  . LEU A 297 ? 0.19099 0.18599 0.08344 -0.05820 -0.00376 0.01017  1303 LEU A CA  
2648 C C   . LEU A 297 ? 0.18938 0.17511 0.08042 -0.05661 -0.00867 0.00770  1303 LEU A C   
2649 O O   . LEU A 297 ? 0.19176 0.18894 0.07966 -0.04885 -0.01715 0.00733  1303 LEU A O   
2650 C CB  . LEU A 297 ? 0.18775 0.19745 0.08332 -0.05065 -0.00982 0.01502  1303 LEU A CB  
2651 C CG  . LEU A 297 ? 0.18546 0.20519 0.07986 -0.06684 -0.01320 0.00840  1303 LEU A CG  
2652 C CD1 . LEU A 297 ? 0.20242 0.20631 0.07616 -0.05068 -0.00514 0.01188  1303 LEU A CD1 
2653 C CD2 . LEU A 297 ? 0.19280 0.24746 0.08304 -0.05912 -0.00779 0.01323  1303 LEU A CD2 
2654 N N   . ALA A 298 ? 0.19930 0.17786 0.08094 -0.05858 -0.01770 0.00459  1304 ALA A N   
2655 C CA  . ALA A 298 ? 0.21166 0.18138 0.08345 -0.05124 -0.02238 -0.00676 1304 ALA A CA  
2656 C C   . ALA A 298 ? 0.20649 0.18643 0.08437 -0.04763 -0.01463 -0.00269 1304 ALA A C   
2657 O O   . ALA A 298 ? 0.20506 0.20324 0.08443 -0.04923 -0.01670 -0.00138 1304 ALA A O   
2658 C CB  . ALA A 298 ? 0.21894 0.18619 0.08312 -0.04154 -0.02853 -0.00752 1304 ALA A CB  
2659 N N   . GLN A 299 ? 0.18678 0.20656 0.08912 -0.06248 -0.00009 -0.00428 1305 GLN A N   
2660 C CA  A GLN A 299 ? 0.19602 0.22238 0.09840 -0.05522 -0.00134 -0.00606 1305 GLN A CA  
2661 C CA  B GLN A 299 ? 0.19539 0.20969 0.09630 -0.05201 0.00065  -0.00780 1305 GLN A CA  
2662 C C   . GLN A 299 ? 0.19803 0.18523 0.09780 -0.05354 -0.00924 -0.01043 1305 GLN A C   
2663 O O   . GLN A 299 ? 0.20497 0.17811 0.10389 -0.03953 -0.00854 -0.00373 1305 GLN A O   
2664 C CB  A GLN A 299 ? 0.20211 0.27215 0.11122 -0.07788 0.00888  -0.00123 1305 GLN A CB  
2665 C CB  B GLN A 299 ? 0.19926 0.22881 0.10411 -0.06423 0.01261  -0.00468 1305 GLN A CB  
2666 C CG  A GLN A 299 ? 0.23264 0.32578 0.12208 -0.05301 0.00686  -0.01623 1305 GLN A CG  
2667 C CG  B GLN A 299 ? 0.23376 0.25249 0.11302 -0.05705 0.01255  -0.00552 1305 GLN A CG  
2668 C CD  A GLN A 299 ? 0.25991 0.38894 0.13102 -0.03023 -0.00378 -0.02865 1305 GLN A CD  
2669 C CD  B GLN A 299 ? 0.26048 0.26648 0.12073 -0.05286 0.01167  -0.01014 1305 GLN A CD  
2670 O OE1 A GLN A 299 ? 0.27454 0.43886 0.13923 -0.00624 -0.01592 -0.04763 1305 GLN A OE1 
2671 O OE1 B GLN A 299 ? 0.28906 0.28254 0.12928 -0.03240 0.01047  -0.00571 1305 GLN A OE1 
2672 N NE2 A GLN A 299 ? 0.27141 0.37385 0.13066 -0.04553 -0.00965 -0.02483 1305 GLN A NE2 
2673 N NE2 B GLN A 299 ? 0.26484 0.27191 0.12020 -0.06060 0.01186  -0.00279 1305 GLN A NE2 
2674 N N   . LEU A 300 ? 0.18647 0.17725 0.09453 -0.05005 -0.01516 -0.01310 1306 LEU A N   
2675 C CA  . LEU A 300 ? 0.17682 0.17392 0.10577 -0.04786 -0.01404 -0.01407 1306 LEU A CA  
2676 C C   . LEU A 300 ? 0.18164 0.17020 0.10140 -0.04046 -0.01744 -0.01065 1306 LEU A C   
2677 O O   . LEU A 300 ? 0.19499 0.19056 0.10716 -0.04673 -0.02717 -0.01489 1306 LEU A O   
2678 C CB  . LEU A 300 ? 0.18509 0.17251 0.11583 -0.04193 -0.01121 -0.00072 1306 LEU A CB  
2679 C CG  . LEU A 300 ? 0.19137 0.18130 0.12810 -0.04258 -0.01494 -0.00560 1306 LEU A CG  
2680 C CD1 . LEU A 300 ? 0.20923 0.19935 0.14264 -0.01191 -0.01520 -0.01976 1306 LEU A CD1 
2681 C CD2 . LEU A 300 ? 0.20054 0.19804 0.13269 -0.04622 -0.01571 -0.00132 1306 LEU A CD2 
2682 N N   . LYS A 301 ? 0.18568 0.17040 0.09847 -0.05353 -0.01500 0.00068  1307 LYS A N   
2683 C CA  . LYS A 301 ? 0.19329 0.18262 0.10222 -0.04502 -0.01251 0.00327  1307 LYS A CA  
2684 C C   . LYS A 301 ? 0.21153 0.18221 0.10674 -0.05289 -0.02177 -0.00071 1307 LYS A C   
2685 O O   . LYS A 301 ? 0.22907 0.19276 0.10907 -0.02413 -0.01612 0.01513  1307 LYS A O   
2686 C CB  . LYS A 301 ? 0.17848 0.19610 0.10990 -0.05275 -0.01275 -0.00639 1307 LYS A CB  
2687 C CG  . LYS A 301 ? 0.18666 0.22738 0.11397 -0.05065 -0.00909 0.00102  1307 LYS A CG  
2688 C CD  . LYS A 301 ? 0.18893 0.26377 0.12061 -0.07950 -0.01768 0.00159  1307 LYS A CD  
2689 C CE  . LYS A 301 ? 0.21632 0.30826 0.12293 -0.08467 -0.01715 0.02042  1307 LYS A CE  
2690 N NZ  . LYS A 301 ? 0.22331 0.38328 0.13210 -0.10379 -0.02158 0.02609  1307 LYS A NZ  
2691 N N   . LYS A 302 ? 0.20788 0.19937 0.11120 -0.05140 -0.01846 -0.01508 1308 LYS A N   
2692 C CA  . LYS A 302 ? 0.23544 0.19567 0.12039 -0.02578 -0.01243 -0.02365 1308 LYS A CA  
2693 C C   . LYS A 302 ? 0.22914 0.18279 0.11888 -0.01180 -0.01539 -0.01886 1308 LYS A C   
2694 O O   . LYS A 302 ? 0.26838 0.19782 0.12808 0.00124  -0.02246 -0.02568 1308 LYS A O   
2695 C CB  . LYS A 302 ? 0.26962 0.23140 0.12995 -0.01490 -0.01106 -0.04830 1308 LYS A CB  
2696 C CG  . LYS A 302 ? 0.32980 0.32152 0.14376 0.03104  -0.00049 -0.06449 1308 LYS A CG  
2697 C CD  . LYS A 302 ? 0.40323 0.40913 0.15203 0.08867  0.00618  -0.07509 1308 LYS A CD  
2698 C CE  . LYS A 302 ? 0.46141 0.47965 0.17078 0.11844  0.00408  -0.07645 1308 LYS A CE  
2699 N NZ  . LYS A 302 ? 0.49590 0.52439 0.18119 0.12990  -0.00450 -0.07774 1308 LYS A NZ  
2700 N N   . ASN A 303 ? 0.20136 0.18368 0.11225 -0.01757 0.00224  -0.02697 1309 ASN A N   
2701 C CA  . ASN A 303 ? 0.18813 0.19191 0.11363 -0.03357 0.00317  -0.01933 1309 ASN A CA  
2702 C C   . ASN A 303 ? 0.19026 0.17926 0.11045 -0.01350 -0.00549 -0.01093 1309 ASN A C   
2703 O O   . ASN A 303 ? 0.19879 0.22325 0.11439 -0.01929 -0.01048 -0.00976 1309 ASN A O   
2704 C CB  . ASN A 303 ? 0.21957 0.23008 0.12316 -0.04230 0.00909  -0.00592 1309 ASN A CB  
2705 C CG  . ASN A 303 ? 0.26552 0.26219 0.13639 -0.02584 0.01860  -0.01638 1309 ASN A CG  
2706 O OD1 . ASN A 303 ? 0.30377 0.26963 0.13755 -0.00080 0.03960  -0.03570 1309 ASN A OD1 
2707 N ND2 . ASN A 303 ? 0.27891 0.27014 0.14255 -0.04585 0.01876  -0.00084 1309 ASN A ND2 
2708 N N   . LYS A 304 ? 0.20742 0.17304 0.10618 -0.00658 0.00114  -0.01151 1310 LYS A N   
2709 C CA  . LYS A 304 ? 0.23202 0.16339 0.10865 -0.01220 -0.00092 -0.00643 1310 LYS A CA  
2710 C C   . LYS A 304 ? 0.17565 0.17049 0.09199 -0.02182 0.00378  0.00779  1310 LYS A C   
2711 O O   . LYS A 304 ? 0.19188 0.17007 0.09356 -0.01194 -0.00559 0.00919  1310 LYS A O   
2712 C CB  . LYS A 304 ? 0.31557 0.15736 0.12783 0.03568  -0.02105 -0.00938 1310 LYS A CB  
2713 C CG  . LYS A 304 ? 0.41940 0.21851 0.15261 0.08428  -0.03101 -0.01338 1310 LYS A CG  
2714 C CD  . LYS A 304 ? 0.49840 0.31770 0.16840 0.09533  -0.02999 -0.02199 1310 LYS A CD  
2715 C CE  . LYS A 304 ? 0.55210 0.40760 0.18456 0.10490  -0.02280 -0.01934 1310 LYS A CE  
2716 N NZ  . LYS A 304 ? 0.57581 0.45465 0.19383 0.11306  -0.02014 -0.02237 1310 LYS A NZ  
2717 N N   . GLN A 305 ? 0.16851 0.14707 0.08860 -0.01493 0.00011  0.00686  1311 GLN A N   
2718 C CA  . GLN A 305 ? 0.15359 0.15695 0.08690 -0.02171 0.00850  0.01140  1311 GLN A CA  
2719 C C   . GLN A 305 ? 0.14998 0.14951 0.08373 -0.02427 -0.00030 0.00493  1311 GLN A C   
2720 O O   . GLN A 305 ? 0.16405 0.15716 0.09674 -0.02632 0.00158  -0.01188 1311 GLN A O   
2721 C CB  . GLN A 305 ? 0.15271 0.17209 0.08402 -0.02776 0.01025  0.00774  1311 GLN A CB  
2722 C CG  . GLN A 305 ? 0.16913 0.15858 0.09104 -0.03154 0.01164  0.00711  1311 GLN A CG  
2723 C CD  . GLN A 305 ? 0.17767 0.17384 0.08916 -0.03638 0.01159  -0.00911 1311 GLN A CD  
2724 O OE1 . GLN A 305 ? 0.25756 0.18919 0.09336 -0.01028 0.02669  -0.00591 1311 GLN A OE1 
2725 N NE2 . GLN A 305 ? 0.16487 0.16767 0.08841 -0.03829 -0.00048 0.00025  1311 GLN A NE2 
2726 N N   . TRP A 306 ? 0.14772 0.17063 0.08718 -0.03266 0.00097  -0.00026 1312 TRP A N   
2727 C CA  . TRP A 306 ? 0.14374 0.18498 0.08358 -0.03256 -0.00475 0.00548  1312 TRP A CA  
2728 C C   . TRP A 306 ? 0.15673 0.17036 0.08345 -0.03871 -0.00721 -0.00964 1312 TRP A C   
2729 O O   . TRP A 306 ? 0.20080 0.17162 0.08842 -0.03090 -0.00581 0.00247  1312 TRP A O   
2730 C CB  . TRP A 306 ? 0.15216 0.21339 0.08031 -0.02449 -0.01463 0.00310  1312 TRP A CB  
2731 C CG  . TRP A 306 ? 0.16199 0.23335 0.07854 -0.03764 -0.01758 -0.00997 1312 TRP A CG  
2732 C CD1 . TRP A 306 ? 0.17524 0.27664 0.08155 -0.02855 -0.00709 -0.02088 1312 TRP A CD1 
2733 C CD2 . TRP A 306 ? 0.16107 0.25874 0.08545 -0.01907 -0.02459 -0.02264 1312 TRP A CD2 
2734 N NE1 . TRP A 306 ? 0.15849 0.30401 0.08338 -0.03398 -0.01100 -0.02147 1312 TRP A NE1 
2735 C CE2 . TRP A 306 ? 0.16812 0.29992 0.08747 0.00151  -0.02375 -0.03276 1312 TRP A CE2 
2736 C CE3 . TRP A 306 ? 0.19829 0.25399 0.08208 0.00919  -0.03419 -0.02117 1312 TRP A CE3 
2737 C CZ2 . TRP A 306 ? 0.17808 0.30133 0.09356 -0.00788 -0.02976 -0.03822 1312 TRP A CZ2 
2738 C CZ3 . TRP A 306 ? 0.22981 0.28544 0.09428 0.03730  -0.04220 -0.03525 1312 TRP A CZ3 
2739 C CH2 . TRP A 306 ? 0.22315 0.30985 0.09533 0.02281  -0.03539 -0.03880 1312 TRP A CH2 
2740 N N   . HIS A 307 ? 0.14069 0.17979 0.08519 -0.03542 0.00428  0.00263  1313 HIS A N   
2741 C CA  . HIS A 307 ? 0.15524 0.17662 0.08985 -0.03150 0.00238  0.01209  1313 HIS A CA  
2742 C C   . HIS A 307 ? 0.15286 0.18431 0.09804 -0.04749 0.00353  -0.00042 1313 HIS A C   
2743 O O   . HIS A 307 ? 0.16399 0.19185 0.13722 -0.03375 0.02459  -0.00770 1313 HIS A O   
2744 C CB  . HIS A 307 ? 0.15486 0.20939 0.08219 -0.01966 -0.00944 0.01246  1313 HIS A CB  
2745 C CG  . HIS A 307 ? 0.16014 0.17758 0.08057 -0.01110 -0.00182 0.02240  1313 HIS A CG  
2746 N ND1 . HIS A 307 ? 0.17464 0.18874 0.08473 -0.02184 0.00207  0.02149  1313 HIS A ND1 
2747 C CD2 . HIS A 307 ? 0.15258 0.18253 0.08289 -0.01241 -0.00218 0.01515  1313 HIS A CD2 
2748 C CE1 . HIS A 307 ? 0.17685 0.17191 0.09181 -0.01813 0.00083  0.02501  1313 HIS A CE1 
2749 N NE2 . HIS A 307 ? 0.15579 0.16482 0.09244 -0.01398 -0.00617 0.01337  1313 HIS A NE2 
2750 N N   . VAL A 308 ? 0.14820 0.20782 0.08665 -0.03586 -0.00653 0.00045  1314 VAL A N   
2751 C CA  . VAL A 308 ? 0.14364 0.21341 0.08476 -0.03417 -0.00553 0.00836  1314 VAL A CA  
2752 C C   . VAL A 308 ? 0.13732 0.20871 0.08450 -0.03937 -0.01361 0.00952  1314 VAL A C   
2753 O O   . VAL A 308 ? 0.17016 0.21295 0.09531 -0.04532 -0.00832 0.02514  1314 VAL A O   
2754 C CB  . VAL A 308 ? 0.17429 0.20673 0.08653 -0.03204 -0.01217 0.00382  1314 VAL A CB  
2755 C CG1 . VAL A 308 ? 0.15457 0.25657 0.08752 -0.02669 -0.01347 0.01241  1314 VAL A CG1 
2756 C CG2 . VAL A 308 ? 0.19331 0.23754 0.08273 -0.02040 -0.01947 0.00483  1314 VAL A CG2 
2757 N N   . GLU A 309 ? 0.12839 0.22323 0.08240 -0.04738 -0.01904 0.02153  1315 GLU A N   
2758 C CA  . GLU A 309 ? 0.13972 0.25524 0.08972 -0.04579 -0.01183 0.04457  1315 GLU A CA  
2759 C C   . GLU A 309 ? 0.12669 0.27204 0.08771 -0.04749 -0.02428 0.02710  1315 GLU A C   
2760 O O   . GLU A 309 ? 0.12239 0.28590 0.08785 -0.04578 -0.00798 0.02677  1315 GLU A O   
2761 C CB  . GLU A 309 ? 0.14527 0.31917 0.11067 -0.04229 -0.00333 0.07016  1315 GLU A CB  
2762 C CG  . GLU A 309 ? 0.16043 0.40333 0.13464 -0.02249 0.00019  0.08706  1315 GLU A CG  
2763 C CD  . GLU A 309 ? 0.24385 0.47500 0.15751 0.00756  0.00356  0.07199  1315 GLU A CD  
2764 O OE1 . GLU A 309 ? 0.24666 0.47144 0.16855 -0.03040 -0.00587 0.07892  1315 GLU A OE1 
2765 O OE2 . GLU A 309 ? 0.31152 0.56265 0.17637 0.07627  -0.00407 0.03978  1315 GLU A OE2 
2766 N N   . VAL A 310 ? 0.12788 0.29025 0.09455 -0.03564 -0.02172 0.02455  1316 VAL A N   
2767 C CA  . VAL A 310 ? 0.12892 0.30622 0.09981 -0.03794 -0.02070 0.02612  1316 VAL A CA  
2768 C C   . VAL A 310 ? 0.12909 0.32976 0.11470 -0.05799 -0.02362 0.01514  1316 VAL A C   
2769 O O   . VAL A 310 ? 0.16168 0.32756 0.14106 -0.05999 -0.00392 0.01915  1316 VAL A O   
2770 C CB  . VAL A 310 ? 0.14393 0.32400 0.09267 -0.03477 -0.02281 0.02207  1316 VAL A CB  
2771 C CG1 . VAL A 310 ? 0.15097 0.33436 0.09133 -0.04160 -0.01669 0.01918  1316 VAL A CG1 
2772 C CG2 . VAL A 310 ? 0.15263 0.33539 0.09298 -0.03965 -0.02073 0.01014  1316 VAL A CG2 
2773 N N   . TYR A 311 ? 0.12529 0.34646 0.10707 -0.04275 -0.02468 0.02435  1317 TYR A N   
2774 C CA  . TYR A 311 ? 0.13686 0.36330 0.10935 -0.05860 -0.01057 0.04003  1317 TYR A CA  
2775 C C   . TYR A 311 ? 0.15056 0.40800 0.12464 -0.05347 -0.01222 0.03868  1317 TYR A C   
2776 O O   . TYR A 311 ? 0.13476 0.43197 0.12614 -0.04365 -0.01708 0.05013  1317 TYR A O   
2777 C CB  . TYR A 311 ? 0.15526 0.32846 0.10126 -0.06136 -0.02091 0.03069  1317 TYR A CB  
2778 C CG  . TYR A 311 ? 0.15338 0.30935 0.09056 -0.04310 -0.01955 0.02876  1317 TYR A CG  
2779 C CD1 . TYR A 311 ? 0.14316 0.31840 0.08937 -0.03734 -0.01261 0.03494  1317 TYR A CD1 
2780 C CD2 . TYR A 311 ? 0.14156 0.26838 0.08307 -0.03727 -0.02190 0.02645  1317 TYR A CD2 
2781 C CE1 . TYR A 311 ? 0.14363 0.30547 0.08495 -0.01221 -0.01103 0.03474  1317 TYR A CE1 
2782 C CE2 . TYR A 311 ? 0.13406 0.25840 0.07362 -0.00652 -0.01968 0.02231  1317 TYR A CE2 
2783 C CZ  . TYR A 311 ? 0.12271 0.26933 0.07675 -0.01745 -0.01663 0.02678  1317 TYR A CZ  
2784 O OH  . TYR A 311 ? 0.13693 0.25875 0.08301 0.00158  -0.01559 0.02174  1317 TYR A OH  
2785 O OXT . TYR A 311 ? 0.16688 0.43090 0.13901 -0.06352 0.00342  0.03815  1317 TYR A OXT 
2786 O O1  A MES B .   ? 0.63604 0.47405 0.32366 0.05612  -0.01739 -0.04320 1401 MES A O1  
2787 O O1  B MES B .   ? 0.59666 0.47582 0.49212 -0.22879 -0.00580 -0.14999 1401 MES A O1  
2788 C C2  A MES B .   ? 0.63155 0.47832 0.32344 0.05478  -0.01734 -0.04455 1401 MES A C2  
2789 C C2  B MES B .   ? 0.60503 0.49525 0.49223 -0.21381 -0.00453 -0.15000 1401 MES A C2  
2790 C C3  A MES B .   ? 0.62296 0.48354 0.32227 0.04596  -0.02142 -0.04980 1401 MES A C3  
2791 C C3  B MES B .   ? 0.61988 0.52413 0.49248 -0.18600 -0.00325 -0.15034 1401 MES A C3  
2792 N N4  A MES B .   ? 0.61321 0.49576 0.32007 0.02305  -0.02967 -0.05823 1401 MES A N4  
2793 N N4  B MES B .   ? 0.63802 0.54415 0.49250 -0.15857 -0.00276 -0.15145 1401 MES A N4  
2794 C C5  A MES B .   ? 0.62370 0.47638 0.32144 0.03641  -0.02206 -0.05130 1401 MES A C5  
2795 C C5  B MES B .   ? 0.61779 0.50621 0.49205 -0.19719 -0.00493 -0.15307 1401 MES A C5  
2796 C C6  A MES B .   ? 0.62669 0.47438 0.32238 0.04314  -0.01940 -0.04626 1401 MES A C6  
2797 C C6  B MES B .   ? 0.60263 0.48290 0.49198 -0.22388 -0.00621 -0.15206 1401 MES A C6  
2798 C C7  A MES B .   ? 0.59759 0.52831 0.31784 -0.00189 -0.04846 -0.07278 1401 MES A C7  
2799 C C7  B MES B .   ? 0.68118 0.59843 0.49304 -0.09109 0.00195  -0.14829 1401 MES A C7  
2800 C C8  A MES B .   ? 0.58291 0.54973 0.31524 -0.02401 -0.07130 -0.08939 1401 MES A C8  
2801 C C8  B MES B .   ? 0.72162 0.64253 0.49346 -0.04215 0.00493  -0.14626 1401 MES A C8  
2802 S S   A MES B .   ? 0.56365 0.56186 0.31185 -0.04975 -0.09612 -0.10354 1401 MES A S   
2803 S S   B MES B .   ? 0.75768 0.68090 0.49383 -0.00060 0.00708  -0.14467 1401 MES A S   
2804 O O1S A MES B .   ? 0.57857 0.59402 0.31279 -0.00861 -0.09327 -0.10474 1401 MES A O1S 
2805 O O1S B MES B .   ? 0.76644 0.69450 0.49385 0.01122  0.00840  -0.14494 1401 MES A O1S 
2806 O O2S A MES B .   ? 0.56296 0.51551 0.31275 -0.07130 -0.09547 -0.09376 1401 MES A O2S 
2807 O O2S B MES B .   ? 0.76577 0.68216 0.49414 0.00306  0.00540  -0.14452 1401 MES A O2S 
2808 O O3S A MES B .   ? 0.56751 0.59140 0.31246 -0.03073 -0.10315 -0.10877 1401 MES A O3S 
2809 O O3S B MES B .   ? 0.76431 0.69100 0.49363 0.00440  0.00756  -0.14501 1401 MES A O3S 
2941 O O   . HOH F .   ? 0.21296 0.27711 0.14211 0.00196  0.01175  0.04052  1502 HOH A O   
2942 O O   . HOH F .   ? 0.14853 0.55433 0.22471 0.02263  -0.00180 -0.10555 1503 HOH A O   
2943 O O   . HOH F .   ? 0.22877 0.56179 0.20838 0.15741  -0.04534 -0.08360 1504 HOH A O   
2944 O O   . HOH F .   ? 0.43587 0.49309 0.24035 0.19614  -0.02931 0.09119  1505 HOH A O   
2945 O O   . HOH F .   ? 0.29645 0.50561 0.15593 0.12095  -0.00436 0.01457  1506 HOH A O   
2946 O O   . HOH F .   ? 0.52659 0.63364 0.43376 0.16784  0.22708  0.21052  1507 HOH A O   
2947 O O   . HOH F .   ? 0.44544 0.38755 0.65914 -0.06632 0.23164  -0.12303 1508 HOH A O   
2948 O O   A HOH F .   ? 0.15214 0.24963 0.07063 -0.03296 -0.01969 -0.00481 1509 HOH A O   
2949 O O   B HOH F .   ? 0.40914 0.31151 0.17454 -0.04444 0.04160  0.04248  1509 HOH A O   
2950 O O   . HOH F .   ? 0.49156 0.27611 0.16186 0.16637  -0.01562 -0.00019 1510 HOH A O   
2951 O O   . HOH F .   ? 0.62603 0.37432 0.34422 0.25905  0.01493  0.06128  1511 HOH A O   
2952 O O   . HOH F .   ? 0.47111 0.59776 0.37685 -0.23634 0.11407  0.06611  1512 HOH A O   
2953 O O   . HOH F .   ? 0.78832 0.49582 0.42697 -0.01917 -0.22411 -0.13865 1513 HOH A O   
2954 O O   . HOH F .   ? 0.44724 0.94210 0.56544 0.26551  -0.17749 -0.14474 1514 HOH A O   
2955 O O   . HOH F .   ? 0.29215 0.63169 0.20168 0.09219  -0.05732 0.02744  1515 HOH A O   
2957 O O   . HOH F .   ? 0.28989 0.54915 0.35645 0.01662  -0.02653 0.11570  1517 HOH A O   
2958 O O   . HOH F .   ? 1.01778 0.62020 0.37923 0.19725  -0.00486 -0.03055 1518 HOH A O   
2959 O O   . HOH F .   ? 0.48764 0.40159 0.30211 -0.16733 -0.04259 -0.02721 1519 HOH A O   
2960 O O   . HOH F .   ? 0.14230 0.50849 0.35716 -0.01699 0.01606  0.00877  1520 HOH A O   
2961 O O   . HOH F .   ? 0.30702 0.33617 0.11728 -0.04525 -0.00876 0.00586  1521 HOH A O   
2962 O O   . HOH F .   ? 0.74956 0.67978 0.30066 0.32479  0.01503  0.09682  1522 HOH A O   
2966 O O   . HOH F .   ? 0.50131 0.41239 0.49068 -0.15811 0.18027  0.02784  1526 HOH A O   
2968 O O   . HOH F .   ? 0.83377 0.47949 0.23537 -0.17907 -0.05821 0.02920  1528 HOH A O   
2969 O O   . HOH F .   ? 0.30681 0.94141 0.55745 -0.14671 0.09415  -0.17392 1529 HOH A O   
2972 O O   . HOH F .   ? 0.53584 0.40747 0.39510 0.04002  -0.12997 -0.10882 1532 HOH A O   
2974 O O   . HOH F .   ? 0.55579 0.44720 0.42297 0.12410  0.04290  -0.13600 1534 HOH A O   
2975 O O   . HOH F .   ? 0.72958 0.30437 0.55418 -0.06269 -0.36013 0.01447  1535 HOH A O   
2976 O O   . HOH F .   ? 0.64239 0.82385 0.37393 -0.19467 0.08112  0.06713  1536 HOH A O   
2977 O O   . HOH F .   ? 0.29660 0.87482 0.43967 -0.12392 0.06769  -0.32136 1537 HOH A O   
2978 O O   . HOH F .   ? 0.11621 0.25114 0.12913 -0.01586 -0.01585 0.03546  1538 HOH A O   
2979 O O   . HOH F .   ? 0.18251 0.54231 0.14337 0.07522  -0.01161 -0.02471 1539 HOH A O   
2980 O O   . HOH F .   ? 0.24213 0.45519 0.28485 0.02789  -0.07441 0.03026  1540 HOH A O   
2981 O O   . HOH F .   ? 0.58792 0.56541 0.58732 0.20697  -0.12941 -0.30745 1541 HOH A O   
2982 O O   . HOH F .   ? 0.14942 0.21150 0.09671 -0.03653 -0.02531 0.03898  1542 HOH A O   
2983 O O   . HOH F .   ? 0.17600 0.33529 0.14498 -0.06046 0.00250  -0.00963 1543 HOH A O   
2984 O O   . HOH F .   ? 0.11549 0.20938 0.09016 0.01150  -0.01942 -0.00011 1544 HOH A O   
2985 O O   . HOH F .   ? 0.31627 0.53065 0.40003 -0.05396 -0.09559 0.01774  1545 HOH A O   
2986 O O   . HOH F .   ? 0.40872 0.44724 0.82095 -0.08361 0.10507  -0.32165 1546 HOH A O   
2987 O O   . HOH F .   ? 0.23058 0.56110 0.16437 0.08837  0.00653  0.07475  1547 HOH A O   
2988 O O   . HOH F .   ? 0.73742 0.37248 0.31849 -0.05313 -0.02550 -0.08560 1548 HOH A O   
2990 O O   . HOH F .   ? 0.27996 0.74346 0.24480 -0.14604 -0.01578 -0.08062 1550 HOH A O   
2991 O O   . HOH F .   ? 0.37221 0.59576 0.20460 0.23377  0.01396  0.05982  1551 HOH A O   
2992 O O   . HOH F .   ? 0.44641 0.64834 0.36892 0.05163  -0.07524 0.11287  1552 HOH A O   
2993 O O   . HOH F .   ? 0.90059 0.40026 0.27727 -0.22199 0.12153  -0.05330 1553 HOH A O   
2994 O O   . HOH F .   ? 0.36640 0.59669 0.37502 0.12360  0.13552  0.23432  1554 HOH A O   
2996 O O   . HOH F .   ? 0.35427 1.10627 0.36336 0.07690  0.07807  0.05611  1556 HOH A O   
2997 O O   A HOH F .   ? 0.14777 0.20658 0.05947 -0.03411 -0.01190 0.01796  1557 HOH A O   
2998 O O   B HOH F .   ? 0.13809 0.25217 0.11607 -0.04850 0.01370  -0.00121 1557 HOH A O   
3000 O O   . HOH F .   ? 0.48773 0.58196 0.20805 0.01008  0.10751  0.09366  1559 HOH A O   
3001 O O   . HOH F .   ? 0.24480 0.34125 0.47227 -0.02541 -0.11300 0.16458  1560 HOH A O   
3002 O O   . HOH F .   ? 0.22309 0.35053 0.11202 0.05343  -0.03340 -0.03298 1561 HOH A O   
3003 O O   . HOH F .   ? 0.29262 0.39950 0.22999 -0.00790 -0.05583 0.10697  1562 HOH A O   
3004 O O   . HOH F .   ? 0.42247 0.27132 0.25508 0.06340  -0.15312 -0.09762 1563 HOH A O   
3005 O O   . HOH F .   ? 0.17858 0.42361 0.19136 -0.05278 -0.00340 0.07582  1564 HOH A O   
3006 O O   . HOH F .   ? 0.29760 0.20997 0.21173 0.04958  0.05978  0.05115  1565 HOH A O   
3007 O O   . HOH F .   ? 0.53224 0.37080 0.38156 -0.04673 -0.00637 0.15440  1566 HOH A O   
3008 O O   . HOH F .   ? 0.30375 0.49093 0.89902 0.05536  0.06198  0.21193  1567 HOH A O   
3009 O O   . HOH F .   ? 0.09889 0.17841 0.06318 0.00865  -0.01258 0.00856  1568 HOH A O   
3010 O O   . HOH F .   ? 0.21665 0.36563 0.10261 -0.06850 -0.02141 0.00766  1569 HOH A O   
3011 O O   . HOH F .   ? 0.55061 0.43484 0.23735 -0.20550 -0.09569 0.09669  1570 HOH A O   
3012 O O   . HOH F .   ? 0.18765 0.32049 0.11083 0.03150  -0.01889 0.01994  1571 HOH A O   
3013 O O   . HOH F .   ? 0.38078 0.26746 0.14999 -0.09460 -0.07957 0.06129  1572 HOH A O   
3014 O O   . HOH F .   ? 0.19968 0.22885 0.13261 -0.03593 0.02408  0.00360  1573 HOH A O   
3015 O O   . HOH F .   ? 0.81768 0.45628 0.65682 -0.24566 -0.05884 -0.19335 1574 HOH A O   
3016 O O   . HOH F .   ? 0.26576 0.49339 0.25149 -0.03076 0.02067  0.16140  1575 HOH A O   
3018 O O   . HOH F .   ? 0.15027 0.24103 0.10899 -0.00797 0.02479  0.03372  1577 HOH A O   
3019 O O   . HOH F .   ? 0.21421 0.40118 0.21972 -0.10008 -0.01060 -0.00394 1578 HOH A O   
3020 O O   . HOH F .   ? 0.13008 0.20257 0.13951 0.00478  -0.02112 0.03555  1579 HOH A O   
3021 O O   . HOH F .   ? 0.18195 0.17280 0.12135 -0.01917 -0.02070 0.01207  1580 HOH A O   
3022 O O   . HOH F .   ? 0.19921 0.20046 0.11719 0.02962  -0.00136 0.01910  1581 HOH A O   
3023 O O   . HOH F .   ? 0.32449 0.24879 0.36744 -0.07191 0.15900  -0.05830 1582 HOH A O   
3024 O O   . HOH F .   ? 0.30384 0.75900 0.40405 0.12021  0.05878  0.18952  1583 HOH A O   
3025 O O   . HOH F .   ? 0.37841 0.70858 0.43682 -0.10961 0.06356  0.15172  1584 HOH A O   
3026 O O   . HOH F .   ? 0.31543 0.44957 0.20923 -0.10194 0.09002  -0.07400 1585 HOH A O   
3027 O O   . HOH F .   ? 0.23836 0.47374 0.12202 0.03322  -0.01358 -0.01452 1586 HOH A O   
3029 O O   . HOH F .   ? 0.12472 0.16437 0.07481 -0.00932 -0.01459 0.01432  1588 HOH A O   
3030 O O   . HOH F .   ? 0.36777 0.36398 0.37824 0.11725  0.18933  0.05668  1589 HOH A O   
3031 O O   . HOH F .   ? 0.12556 0.17415 0.09397 -0.00466 0.00930  0.01753  1590 HOH A O   
3032 O O   . HOH F .   ? 0.27057 0.20870 0.13248 -0.02897 0.00201  0.02412  1591 HOH A O   
3033 O O   . HOH F .   ? 0.52016 0.37938 0.36214 0.21490  -0.21559 -0.12830 1592 HOH A O   
3034 O O   . HOH F .   ? 0.19945 0.47420 0.23327 -0.06591 0.00051  -0.15382 1593 HOH A O   
3035 O O   . HOH F .   ? 0.15861 0.20333 0.11111 0.01720  0.00114  0.03939  1594 HOH A O   
3036 O O   . HOH F .   ? 0.18926 0.49828 0.15861 0.00162  -0.02735 -0.00333 1595 HOH A O   
3037 O O   . HOH F .   ? 0.21761 0.31548 0.14380 0.05804  -0.03030 -0.05353 1596 HOH A O   
3038 O O   . HOH F .   ? 0.53173 0.30634 0.21829 -0.15894 0.12902  -0.02863 1597 HOH A O   
3041 O O   . HOH F .   ? 0.22459 0.84333 0.47889 0.07691  -0.02148 -0.01365 1599 HOH A O   
3042 O O   . HOH F .   ? 0.16578 0.26463 0.10231 0.05502  -0.04421 0.01077  1600 HOH A O   
3043 O O   . HOH F .   ? 0.29223 0.15802 0.11451 -0.05045 0.00231  -0.00534 1601 HOH A O   
3044 O O   . HOH F .   ? 0.32849 0.27379 0.30005 -0.09516 -0.11068 0.11008  1602 HOH A O   
3045 O O   . HOH F .   ? 0.30787 0.53168 0.22690 0.10491  -0.01043 0.12501  1603 HOH A O   
3048 O O   . HOH F .   ? 0.89888 0.43934 0.33046 0.13099  0.01216  0.07545  1605 HOH A O   
3049 O O   . HOH F .   ? 0.22240 0.28326 0.14098 0.03177  -0.00350 0.03354  1606 HOH A O   
3050 O O   . HOH F .   ? 0.13452 0.16777 0.07981 -0.01223 -0.01370 0.02441  1607 HOH A O   
3051 O O   . HOH F .   ? 0.20105 0.39770 0.42633 -0.04982 0.06266  -0.06974 1608 HOH A O   
3052 O O   . HOH F .   ? 0.16028 0.22443 0.10060 0.02560  -0.01748 0.01329  1609 HOH A O   
3053 O O   . HOH F .   ? 0.83415 0.32608 0.56453 -0.06662 -0.01734 -0.09452 1610 HOH A O   
3054 O O   . HOH F .   ? 0.17873 0.35298 0.14781 -0.09196 0.00775  0.01197  1611 HOH A O   
3055 O O   . HOH F .   ? 0.16760 0.21834 0.11510 0.00538  -0.00903 0.01228  1612 HOH A O   
3057 O O   . HOH F .   ? 0.35950 0.26545 0.21546 0.04062  0.05137  -0.03907 1614 HOH A O   
3058 O O   . HOH F .   ? 0.15217 0.56194 0.16489 -0.02820 -0.00824 0.03286  1615 HOH A O   
3059 O O   . HOH F .   ? 0.36080 0.23001 0.10876 -0.11325 0.00555  0.00874  1616 HOH A O   
3060 O O   . HOH F .   ? 0.16331 0.18881 0.09012 0.01525  -0.00746 0.01038  1617 HOH A O   
3061 O O   . HOH F .   ? 0.11879 0.18780 0.08478 -0.00617 0.01134  0.02650  1618 HOH A O   
3062 O O   . HOH F .   ? 0.26852 0.31016 0.23496 0.05812  0.07808  -0.00370 1619 HOH A O   
3063 O O   . HOH F .   ? 0.57950 0.22805 0.22161 0.03643  0.07957  -0.03637 1620 HOH A O   
3064 O O   . HOH F .   ? 0.30500 0.17083 0.12633 -0.01059 -0.02700 0.02107  1621 HOH A O   
3065 O O   . HOH F .   ? 0.26607 0.20349 0.19662 0.03763  0.02055  -0.04333 1622 HOH A O   
3066 O O   . HOH F .   ? 0.24063 0.24373 0.13165 0.04903  0.00275  0.00307  1623 HOH A O   
3067 O O   . HOH F .   ? 0.34999 0.62270 0.43961 0.06973  0.03299  0.18874  1624 HOH A O   
3068 O O   . HOH F .   ? 0.31372 0.55417 0.18965 0.21663  0.01530  0.05169  1625 HOH A O   
3069 O O   . HOH F .   ? 0.13321 0.21697 0.06773 -0.02136 0.00077  0.00418  1626 HOH A O   
3070 O O   . HOH F .   ? 0.27813 0.27377 0.30426 -0.07122 0.01923  0.09120  1627 HOH A O   
3071 O O   . HOH F .   ? 0.23309 0.28090 0.21773 -0.00675 -0.03728 -0.08324 1628 HOH A O   
3072 O O   . HOH F .   ? 0.12794 0.19376 0.07868 -0.01321 0.00183  0.02458  1629 HOH A O   
3073 O O   . HOH F .   ? 0.23636 0.19761 0.09634 -0.02878 -0.02360 0.01807  1630 HOH A O   
3074 O O   . HOH F .   ? 0.36037 0.78587 0.26145 -0.25158 -0.03865 0.02773  1631 HOH A O   
3077 O O   A HOH F .   ? 0.12154 0.18397 0.08332 0.01842  -0.00732 0.01126  1633 HOH A O   
3078 O O   B HOH F .   ? 0.23251 0.44037 0.18852 0.03406  -0.00438 -0.02930 1633 HOH A O   
3079 O O   . HOH F .   ? 0.19497 0.62337 0.27094 -0.08370 -0.03038 0.17869  1634 HOH A O   
3080 O O   . HOH F .   ? 0.16148 0.20647 0.11421 0.02146  -0.01977 -0.01998 1635 HOH A O   
3082 O O   . HOH F .   ? 0.36310 0.69692 0.51791 0.11183  -0.00488 -0.05358 1637 HOH A O   
3083 O O   . HOH F .   ? 0.21518 0.17979 0.17466 -0.05025 -0.01644 0.00217  1638 HOH A O   
3084 O O   . HOH F .   ? 0.14532 0.42184 0.18779 0.03993  -0.04193 -0.02491 1639 HOH A O   
3085 O O   . HOH F .   ? 0.88517 0.32310 0.56207 0.08726  0.39313  0.04215  1640 HOH A O   
3086 O O   A HOH F .   ? 0.09780 0.32915 0.08701 0.04212  -0.00228 0.00785  1641 HOH A O   
3087 O O   B HOH F .   ? 0.32419 0.28597 0.14403 -0.05028 0.08839  -0.01666 1641 HOH A O   
3089 O O   . HOH F .   ? 0.61310 0.44341 1.04015 -0.06768 0.14230  0.27545  1643 HOH A O   
3090 O O   . HOH F .   ? 0.28781 0.64858 0.51398 -0.00085 -0.00599 -0.27420 1644 HOH A O   
3091 O O   . HOH F .   ? 0.10753 0.16862 0.07602 -0.00268 -0.00078 0.00312  1645 HOH A O   
3092 O O   . HOH F .   ? 0.31551 0.46517 0.96585 -0.05846 -0.18035 0.10264  1646 HOH A O   
3093 O O   . HOH F .   ? 0.22099 0.42967 0.25945 -0.06443 -0.09237 0.14384  1647 HOH A O   
3094 O O   . HOH F .   ? 0.34562 0.49567 0.56888 0.17584  -0.18280 -0.09254 1648 HOH A O   
3095 O O   . HOH F .   ? 0.59005 0.39801 1.10206 -0.07783 0.36117  -0.01498 1649 HOH A O   
3096 O O   . HOH F .   ? 0.18592 0.37749 0.18067 -0.00383 0.02298  0.01886  1650 HOH A O   
3097 O O   . HOH F .   ? 0.11628 0.19354 0.07984 -0.01682 -0.00029 0.01004  1651 HOH A O   
3099 O O   . HOH F .   ? 0.46396 0.52049 0.30810 -0.17547 -0.17725 0.05752  1653 HOH A O   
3101 O O   . HOH F .   ? 0.59128 0.33696 1.02650 -0.10318 -0.26736 0.01448  1655 HOH A O   
3102 O O   . HOH F .   ? 0.17682 0.20366 0.10340 0.02583  0.00991  0.02127  1656 HOH A O   
3103 O O   . HOH F .   ? 0.11918 0.18229 0.09982 -0.00301 -0.00634 0.01307  1657 HOH A O   
3104 O O   . HOH F .   ? 0.14114 0.19870 0.11852 0.00735  0.00255  0.02896  1658 HOH A O   
3105 O O   . HOH F .   ? 0.56179 0.51705 0.21661 0.29178  -0.00919 -0.03035 1659 HOH A O   
3106 O O   . HOH F .   ? 0.19314 0.42347 0.62007 0.02909  -0.10949 0.02399  1660 HOH A O   
3107 O O   . HOH F .   ? 0.53627 0.42978 0.61710 -0.23181 0.16607  -0.20196 1661 HOH A O   
3108 O O   . HOH F .   ? 0.10328 0.18107 0.09170 -0.00438 -0.00655 0.01687  1662 HOH A O   
3109 O O   . HOH F .   ? 0.18262 0.26125 0.13100 -0.04138 -0.02837 -0.00086 1663 HOH A O   
3110 O O   . HOH F .   ? 0.15552 0.38114 0.14477 -0.00316 -0.02394 0.00915  1664 HOH A O   
3111 O O   . HOH F .   ? 0.27164 0.41439 0.18582 -0.05698 0.04020  -0.01089 1665 HOH A O   
3112 O O   . HOH F .   ? 0.15156 0.27145 0.12143 0.01776  -0.02398 -0.04310 1666 HOH A O   
3113 O O   . HOH F .   ? 0.33772 0.31877 0.33987 0.01427  -0.18499 0.07195  1667 HOH A O   
3114 O O   . HOH F .   ? 0.70837 0.80394 0.32055 -0.44968 0.00669  -0.01497 1668 HOH A O   
3115 O O   . HOH F .   ? 0.21457 0.28005 0.22204 -0.04028 0.07588  -0.06592 1669 HOH A O   
3116 O O   . HOH F .   ? 0.20471 0.36395 0.16817 -0.07154 0.00705  0.02875  1670 HOH A O   
3117 O O   . HOH F .   ? 0.77975 0.48554 0.27065 0.12823  -0.13859 -0.04432 1671 HOH A O   
3118 O O   . HOH F .   ? 0.34883 0.26577 0.17430 0.04821  -0.03632 -0.04104 1672 HOH A O   
3121 O O   . HOH F .   ? 0.33183 0.31925 0.33360 0.08984  -0.15689 -0.01756 1674 HOH A O   
3122 O O   . HOH F .   ? 0.59020 0.31339 0.81431 -0.09409 -0.30315 0.14766  1675 HOH A O   
3123 O O   . HOH F .   ? 0.31849 0.81142 0.35125 -0.06151 0.05024  0.15301  1676 HOH A O   
3124 O O   . HOH F .   ? 0.14323 0.16275 0.08987 -0.01695 -0.01455 0.01570  1677 HOH A O   
3125 O O   . HOH F .   ? 0.22766 0.29332 0.15792 -0.00489 -0.02295 -0.01508 1678 HOH A O   
3126 O O   . HOH F .   ? 0.20014 0.49212 0.23404 -0.03455 0.07925  -0.08606 1679 HOH A O   
3127 O O   . HOH F .   ? 0.16009 0.25896 0.08228 -0.02760 0.01204  0.00834  1680 HOH A O   
3128 O O   . HOH F .   ? 0.20558 0.34357 0.18478 -0.05642 0.01254  0.09691  1681 HOH A O   
3129 O O   . HOH F .   ? 0.38010 0.65793 0.56026 0.00994  0.21021  -0.18758 1682 HOH A O   
3130 O O   . HOH F .   ? 0.59246 0.35658 0.24889 0.09439  -0.01687 -0.04522 1683 HOH A O   
3131 O O   . HOH F .   ? 0.18846 0.28044 0.19509 0.00606  0.02428  -0.05432 1684 HOH A O   
3134 O O   . HOH F .   ? 0.32474 0.25114 0.11861 -0.03356 0.02029  0.00861  1687 HOH A O   
3135 O O   . HOH F .   ? 0.24462 0.27529 0.18528 -0.08325 -0.02241 0.07907  1688 HOH A O   
3136 O O   . HOH F .   ? 0.16075 0.27221 0.17363 -0.02559 -0.00398 0.03600  1689 HOH A O   
3137 O O   . HOH F .   ? 0.25848 0.15435 0.12266 -0.03136 -0.01785 0.02302  1690 HOH A O   
3138 O O   . HOH F .   ? 0.38462 0.49297 0.31446 0.21611  -0.15127 -0.17266 1691 HOH A O   
3139 O O   . HOH F .   ? 0.17522 0.23766 0.16642 0.00295  -0.00182 -0.00939 1692 HOH A O   
3140 O O   . HOH F .   ? 0.61014 0.29677 0.36025 0.08791  0.20067  0.07141  1693 HOH A O   
3141 O O   . HOH F .   ? 0.56542 0.33217 0.16889 -0.10668 -0.05464 0.04653  1694 HOH A O   
3142 O O   . HOH F .   ? 0.43731 0.23106 0.12172 -0.09156 0.01201  0.01227  1695 HOH A O   
3147 O O   . HOH F .   ? 0.25370 0.60166 0.30215 -0.04704 -0.10123 -0.02887 1699 HOH A O   
3149 O O   A HOH F .   ? 0.16133 0.27768 0.17223 0.07009  -0.03727 -0.07653 1701 HOH A O   
3150 O O   B HOH F .   ? 0.17921 0.45234 0.23649 0.06599  -0.02198 -0.16786 1701 HOH A O   
3151 O O   . HOH F .   ? 0.23693 0.19638 0.09698 -0.04425 0.04200  0.00746  1702 HOH A O   
3152 O O   . HOH F .   ? 0.34938 0.28624 0.15430 0.01165  0.03532  0.01913  1703 HOH A O   
3153 O O   . HOH F .   ? 0.76053 0.30838 1.14432 0.05784  -0.08508 -0.08923 1704 HOH A O   
3154 O O   . HOH F .   ? 0.86801 0.37558 0.24434 0.03758  -0.00277 0.06370  1705 HOH A O   
3155 O O   . HOH F .   ? 0.39196 0.24169 0.15991 -0.07224 0.04750  -0.01138 1706 HOH A O   
3156 O O   . HOH F .   ? 0.48648 0.31056 0.29494 0.16770  0.07543  0.03822  1707 HOH A O   
3157 O O   . HOH F .   ? 0.14857 0.32950 0.12451 -0.01421 0.01162  0.02244  1708 HOH A O   
3158 O O   . HOH F .   ? 0.14091 0.34556 0.16336 -0.00302 -0.02444 0.02153  1709 HOH A O   
3159 O O   . HOH F .   ? 0.37821 0.28399 0.13404 0.00299  0.00410  0.00605  1710 HOH A O   
3160 O O   . HOH F .   ? 0.21298 0.49075 0.59361 -0.12564 0.01175  0.07808  1711 HOH A O   
3161 O O   . HOH F .   ? 0.56553 0.30717 0.38243 -0.14706 0.03641  -0.11355 1712 HOH A O   
3162 O O   . HOH F .   ? 0.48182 0.45847 0.84667 0.14275  0.20393  -0.03233 1713 HOH A O   
3164 O O   . HOH F .   ? 0.70015 0.40061 0.79162 0.11834  0.12764  -0.06779 1715 HOH A O   
3165 O O   . HOH F .   ? 0.16767 0.36390 0.11811 0.00334  -0.00473 0.01012  1716 HOH A O   
3166 O O   . HOH F .   ? 0.11178 0.17095 0.07860 -0.01717 -0.00846 0.00904  1717 HOH A O   
3167 O O   . HOH F .   ? 0.36160 0.36652 0.70692 -0.03370 0.16383  -0.02699 1718 HOH A O   
3169 O O   . HOH F .   ? 0.73176 0.87759 0.30100 0.16873  0.14020  -0.01977 1720 HOH A O   
3170 O O   . HOH F .   ? 0.28387 0.62297 0.33525 -0.12632 -0.05992 0.17615  1721 HOH A O   
3171 O O   . HOH F .   ? 0.12929 0.20821 0.08982 -0.00614 0.00769  0.02460  1722 HOH A O   
3172 O O   . HOH F .   ? 0.68350 0.73977 0.24808 0.02302  -0.16826 0.01545  1723 HOH A O   
3173 O O   . HOH F .   ? 0.11689 0.21793 0.09220 -0.00874 -0.00918 0.01583  1724 HOH A O   
3174 O O   . HOH F .   ? 0.26951 0.29975 0.17073 -0.00632 -0.06021 -0.05940 1725 HOH A O   
3175 O O   . HOH F .   ? 0.39225 0.27897 0.20023 -0.01034 -0.11916 -0.04119 1726 HOH A O   
3176 O O   . HOH F .   ? 0.12934 0.16334 0.07888 -0.00869 -0.00399 0.01793  1727 HOH A O   
3177 O O   . HOH F .   ? 0.26369 0.65020 0.44615 -0.16314 0.08476  -0.16130 1728 HOH A O   
3178 O O   . HOH F .   ? 0.44619 0.55066 0.63787 0.13934  0.26900  0.24734  1729 HOH A O   
3179 O O   . HOH F .   ? 0.12734 0.24891 0.09658 0.00227  -0.00520 0.00099  1730 HOH A O   
3180 O O   . HOH F .   ? 0.23173 0.43953 0.25224 0.03527  -0.02705 0.15496  1731 HOH A O   
3181 O O   . HOH F .   ? 0.86645 0.79750 0.30263 0.00996  -0.01934 0.21695  1732 HOH A O   
3182 O O   . HOH F .   ? 0.43508 0.47323 0.26748 -0.05950 -0.02468 0.13417  1733 HOH A O   
3183 O O   . HOH F .   ? 0.75336 0.31534 0.58325 -0.03716 0.37575  -0.06529 1734 HOH A O   
3185 O O   . HOH F .   ? 0.57182 0.40085 0.86754 -0.01443 0.22946  0.05518  1736 HOH A O   
3186 O O   . HOH F .   ? 0.59354 0.27993 0.20721 -0.10787 -0.01938 -0.01834 1737 HOH A O   
3187 O O   . HOH F .   ? 0.40220 0.62650 0.31517 -0.18528 0.14913  -0.14417 1738 HOH A O   
3188 O O   . HOH F .   ? 0.23142 0.25089 0.13236 0.01536  -0.01676 0.04005  1739 HOH A O   
3190 O O   . HOH F .   ? 0.36547 0.39733 0.25786 0.04487  -0.14457 0.01533  1741 HOH A O   
3191 O O   . HOH F .   ? 0.22924 0.21408 0.22775 -0.02549 -0.03659 0.00461  1742 HOH A O   
3192 O O   . HOH F .   ? 0.50708 0.50334 0.31912 -0.24618 -0.17710 0.13935  1743 HOH A O   
3193 O O   . HOH F .   ? 0.28167 0.30062 0.11073 0.00840  0.02578  -0.01088 1744 HOH A O   
3194 O O   . HOH F .   ? 0.25822 0.21462 0.13181 0.00022  0.00268  0.01934  1745 HOH A O   
3195 O O   . HOH F .   ? 0.50587 0.89023 0.51157 -0.30165 -0.17318 0.12907  1746 HOH A O   
3196 O O   . HOH F .   ? 0.57719 0.49976 0.21270 0.18496  0.04322  0.09064  1747 HOH A O   
3197 O O   . HOH F .   ? 0.33029 0.56151 0.62725 -0.12526 -0.13762 0.03352  1748 HOH A O   
3198 O O   . HOH F .   ? 0.37400 0.45319 0.52923 0.07264  0.06001  0.16551  1749 HOH A O   
3199 O O   . HOH F .   ? 0.17417 0.21634 0.11447 0.01457  -0.01307 -0.01995 1750 HOH A O   
3200 O O   . HOH F .   ? 0.34995 0.34318 0.39762 -0.06076 0.09540  -0.20307 1751 HOH A O   
3202 O O   . HOH F .   ? 0.51468 0.37428 0.15975 0.17421  -0.00420 -0.01458 1753 HOH A O   
3203 O O   . HOH F .   ? 0.18982 0.42475 0.13797 0.07882  -0.02264 -0.04819 1754 HOH A O   
3204 O O   . HOH F .   ? 0.14970 0.51356 0.17022 0.01416  -0.01564 0.07786  1755 HOH A O   
3205 O O   . HOH F .   ? 0.19844 0.35950 0.13583 -0.04002 0.01631  0.01564  1756 HOH A O   
3206 O O   . HOH F .   ? 0.17843 0.28294 0.14862 0.00876  0.02385  0.02005  1757 HOH A O   
3208 O O   . HOH F .   ? 0.47902 0.53466 0.22175 -0.03980 0.11710  0.05313  1759 HOH A O   
3209 O O   . HOH F .   ? 0.28117 0.28230 0.38173 0.07967  0.08648  0.10441  1760 HOH A O   
3210 O O   . HOH F .   ? 0.56471 0.84198 0.39934 0.25630  -0.11740 0.10645  1761 HOH A O   
3211 O O   . HOH F .   ? 0.61895 0.50625 0.23430 0.10297  -0.04947 -0.13656 1762 HOH A O   
3212 O O   . HOH F .   ? 0.54868 0.91011 0.30893 -0.23970 -0.09054 0.12197  1763 HOH A O   
3213 O O   . HOH F .   ? 0.31454 0.58627 0.94176 -0.09328 -0.14441 -0.08839 1764 HOH A O   
3214 O O   . HOH F .   ? 0.59359 0.25658 0.36670 -0.07136 -0.08816 0.01934  1765 HOH A O   
3215 O O   . HOH F .   ? 0.35241 0.31677 0.21518 -0.02508 -0.07747 -0.01297 1766 HOH A O   
3216 O O   . HOH F .   ? 0.37939 0.47861 0.23008 -0.00532 -0.10238 -0.11618 1767 HOH A O   
3217 O O   . HOH F .   ? 0.43992 0.37652 0.13569 -0.07797 -0.05602 0.01776  1768 HOH A O   
3218 O O   . HOH F .   ? 0.28989 0.60204 0.68614 -0.04011 -0.01563 0.03325  1769 HOH A O   
3220 O O   . HOH F .   ? 0.37002 0.32033 0.21369 0.17716  0.01798  0.03878  1771 HOH A O   
3221 O O   . HOH F .   ? 0.10429 0.20097 0.08135 0.00186  -0.01057 0.00297  1772 HOH A O   
3222 O O   . HOH F .   ? 0.31353 0.38875 0.37725 -0.10952 0.09848  -0.19028 1773 HOH A O   
3223 O O   . HOH F .   ? 0.45145 0.21008 0.18613 0.10958  0.05390  0.01996  1774 HOH A O   
3224 O O   . HOH F .   ? 0.34345 0.73131 0.79198 -0.05449 0.22054  -0.17952 1775 HOH A O   
3225 O O   . HOH F .   ? 0.22009 0.20393 0.14428 0.04982  0.01758  0.00789  1776 HOH A O   
3227 O O   . HOH F .   ? 0.58337 0.70989 0.70569 -0.01724 0.25689  -0.00100 1778 HOH A O   
3228 O O   . HOH F .   ? 0.17618 0.46929 0.33830 0.04280  0.00635  0.14548  1779 HOH A O   
3229 O O   . HOH F .   ? 1.00223 0.60854 0.52001 -0.11261 -0.25536 0.18362  1780 HOH A O   
3230 O O   . HOH F .   ? 0.42592 0.32891 0.33844 -0.01654 0.05270  -0.13375 1781 HOH A O   
3231 O O   . HOH F .   ? 0.22261 0.38046 0.20219 0.07582  -0.04705 0.01586  1782 HOH A O   
3232 O O   . HOH F .   ? 0.48375 0.62967 0.59012 0.04891  0.25616  0.21757  1783 HOH A O   
3233 O O   . HOH F .   ? 0.32746 0.48252 0.65266 -0.13859 -0.18787 0.29955  1784 HOH A O   
3234 O O   . HOH F .   ? 0.79569 0.28859 0.23919 -0.18042 -0.09133 0.03880  1785 HOH A O   
3236 O O   . HOH F .   ? 0.81008 0.37581 1.11846 -0.03870 -0.21063 0.17726  1787 HOH A O   
3237 O O   . HOH F .   ? 0.33636 0.15745 0.12279 -0.00137 -0.01009 0.03403  1788 HOH A O   
3238 O O   . HOH F .   ? 0.25110 0.37860 0.26154 -0.09592 0.03032  -0.13246 1789 HOH A O   
3239 O O   . HOH F .   ? 0.36286 0.31860 0.32669 -0.06778 -0.08567 0.11731  1790 HOH A O   
3240 O O   . HOH F .   ? 0.32815 0.28586 0.44079 -0.07684 -0.12113 0.11353  1791 HOH A O   
3242 O O   . HOH F .   ? 0.65805 0.31713 0.80143 -0.05800 -0.29343 0.06767  1793 HOH A O   
3243 O O   . HOH F .   ? 0.22161 0.30459 0.12444 0.04002  0.00544  -0.02666 1794 HOH A O   
3245 O O   . HOH F .   ? 0.36234 0.59671 0.76788 -0.10459 0.04822  0.30592  1796 HOH A O   
3246 O O   . HOH F .   ? 0.49626 0.60804 0.72137 -0.11981 0.13908  0.28952  1797 HOH A O   
3248 O O   . HOH F .   ? 0.51497 0.40705 0.81405 -0.07960 0.16041  -0.28902 1799 HOH A O   
3249 O O   . HOH F .   ? 0.24237 0.32218 0.12147 -0.06256 0.00105  -0.00504 1800 HOH A O   
3250 O O   . HOH F .   ? 1.01394 0.98925 0.76982 0.32340  -0.35381 -0.28243 1801 HOH A O   
3253 O O   . HOH F .   ? 0.32313 0.45985 0.23821 -0.10386 0.10719  -0.10874 1804 HOH A O   
3254 O O   . HOH F .   ? 0.57396 0.37961 0.66269 0.03104  -0.17047 0.06018  1805 HOH A O   
3255 O O   . HOH F .   ? 0.33228 0.70617 0.40618 -0.02778 -0.07043 0.12407  1806 HOH A O   
3257 O O   . HOH F .   ? 0.65805 0.44134 0.29684 -0.05100 -0.15918 -0.01096 1808 HOH A O   
3258 O O   . HOH F .   ? 0.37478 0.28813 0.15964 -0.04288 0.00923  0.00893  1809 HOH A O   
3259 O O   . HOH F .   ? 0.31790 0.59983 0.85312 -0.09231 -0.18995 0.18316  1810 HOH A O   
3260 O O   . HOH F .   ? 0.39419 0.83619 0.30523 0.26870  0.01414  -0.06104 1811 HOH A O   
3261 O O   . HOH F .   ? 0.59389 0.36880 0.25859 0.04315  0.05574  -0.02493 1812 HOH A O   
3262 O O   . HOH F .   ? 0.28929 0.26383 0.33729 0.01670  -0.10786 -0.00269 1813 HOH A O   
3263 O O   . HOH F .   ? 0.20932 0.26188 0.14133 -0.02560 0.05331  0.02498  1814 HOH A O   
3264 O O   . HOH F .   ? 0.50206 0.39622 0.31097 -0.11311 -0.04234 -0.14930 1815 HOH A O   
3265 O O   . HOH F .   ? 0.77318 0.68919 0.46612 0.15796  -0.20094 0.20621  1816 HOH A O   
3269 O O   . HOH F .   ? 0.60517 0.64386 0.93296 0.15198  0.15356  -0.32080 1820 HOH A O   
3270 O O   . HOH F .   ? 0.63514 0.43839 0.56768 0.04279  0.03951  0.08364  1821 HOH A O   
3274 O O   . HOH F .   ? 0.21610 0.32732 0.13557 0.03940  -0.00583 0.01866  1825 HOH A O   
3275 O O   . HOH F .   ? 0.74282 0.65177 0.21713 -0.04649 0.06126  -0.08895 1826 HOH A O   
3276 O O   . HOH F .   ? 0.50950 0.44935 0.74329 -0.02281 0.26624  0.06231  1827 HOH A O   
3277 O O   . HOH F .   ? 0.57195 0.79314 0.43090 -0.34753 -0.10700 0.13316  1828 HOH A O   
3279 O O   . HOH F .   ? 0.68465 0.41482 0.62376 0.00760  0.06086  -0.07892 1830 HOH A O   
3280 O O   . HOH F .   ? 0.49988 0.67578 0.69329 -0.05771 -0.16333 -0.28961 1831 HOH A O   
3281 O O   . HOH F .   ? 0.64397 0.36535 0.57130 0.06592  0.06490  0.05736  1832 HOH A O   
3282 O O   . HOH F .   ? 0.71589 0.35791 1.05916 0.09213  -0.01443 -0.17901 1833 HOH A O   
3283 O O   . HOH F .   ? 0.66874 0.63683 0.87124 -0.09452 0.05572  0.00263  1834 HOH A O   
3284 O O   . HOH F .   ? 0.63908 0.52229 0.31189 -0.08377 -0.04211 0.15297  1835 HOH A O   
3285 O O   . HOH F .   ? 0.46125 0.70205 0.39447 0.08476  -0.09979 0.13969  1836 HOH A O   
3287 O O   . HOH F .   ? 0.35309 0.60321 0.66627 -0.13209 0.09119  -0.18392 1838 HOH A O   
3288 O O   . HOH F .   ? 0.57626 0.50133 0.32862 -0.11604 0.01702  0.17067  1839 HOH A O   
3291 O O   . HOH F .   ? 0.28972 0.61344 0.45958 -0.08059 -0.14191 0.04870  1841 HOH A O   
3292 O O   . HOH F .   ? 0.66290 0.84385 0.49787 0.28792  -0.19483 -0.04849 1842 HOH A O   
3293 O O   . HOH F .   ? 0.59785 0.26805 0.23931 -0.03494 -0.10727 0.08389  1843 HOH A O   
3295 O O   . HOH F .   ? 0.65822 0.91705 0.58516 0.20457  0.20611  -0.08547 1845 HOH A O   
3296 O O   . HOH F .   ? 0.50005 0.50057 0.27321 0.19450  0.15213  0.12499  1846 HOH A O   
3297 O O   . HOH F .   ? 0.20745 0.45669 0.18615 -0.03644 -0.01169 -0.03802 1847 HOH A O   
3301 O O   . HOH F .   ? 0.34863 0.34501 0.60452 -0.00738 0.03581  -0.13180 1851 HOH A O   
3302 O O   . HOH F .   ? 0.31469 0.63557 0.56769 0.02079  0.01844  0.24659  1852 HOH A O   
3304 O O   . HOH F .   ? 0.48880 0.99179 0.32217 -0.34259 0.02254  0.01488  1854 HOH A O   
3305 O O   . HOH F .   ? 0.21544 0.38260 0.51137 -0.01159 -0.13305 0.13097  1855 HOH A O   
3306 O O   . HOH F .   ? 0.45831 0.93298 0.57395 0.24332  -0.02814 -0.23642 1856 HOH A O   
3308 O O   . HOH F .   ? 0.66665 0.47339 0.36568 0.08152  -0.13079 -0.09031 1858 HOH A O   
3309 O O   . HOH F .   ? 0.70160 0.55303 0.40712 0.06872  0.11738  0.17434  1859 HOH A O   
3313 O O   . HOH F .   ? 0.69620 0.83928 0.54205 -0.28677 -0.24106 0.31000  1862 HOH A O   
3315 O O   . HOH F .   ? 0.98218 0.41567 0.30826 0.16182  0.16870  0.02146  1864 HOH A O   
3316 O O   . HOH F .   ? 0.48775 0.46656 0.92635 -0.10637 0.19601  0.08404  1865 HOH A O   
3317 O O   . HOH F .   ? 0.48122 0.60348 0.32830 -0.11036 0.14748  -0.05367 1866 HOH A O   
3318 O O   . HOH F .   ? 0.21172 0.52612 0.56224 -0.02719 -0.07192 -0.09523 1867 HOH A O   
3319 O O   . HOH F .   ? 0.23945 0.29948 0.15496 -0.01873 -0.00880 0.05948  1868 HOH A O   
3320 O O   . HOH F .   ? 0.74287 0.79482 0.52354 -0.19075 -0.05653 0.34322  1869 HOH A O   
3321 O O   . HOH F .   ? 0.34078 1.16675 0.33667 -0.02182 -0.01491 -0.09925 1870 HOH A O   
3322 O O   . HOH F .   ? 0.38623 0.44172 0.73077 -0.03230 0.17543  -0.11916 1871 HOH A O   
3323 O O   . HOH F .   ? 0.43416 0.26591 0.46145 0.04333  0.06454  0.18148  1872 HOH A O   
3324 O O   . HOH F .   ? 0.21178 0.26233 0.27602 -0.02132 -0.01860 0.03567  1873 HOH A O   
3325 O O   . HOH F .   ? 0.32396 0.41847 0.45831 -0.04313 -0.07982 -0.03872 1874 HOH A O   
3326 O O   . HOH F .   ? 0.21359 0.43031 0.32739 -0.10404 0.00837  0.01603  1875 HOH A O   
3327 O O   . HOH F .   ? 0.36108 0.35053 0.36778 -0.03324 0.12486  0.09093  1876 HOH A O   
3328 O O   . HOH F .   ? 0.43798 0.60693 0.26255 0.22830  -0.11221 -0.13346 1877 HOH A O   
3329 O O   . HOH F .   ? 0.24723 0.27371 0.19738 -0.01703 0.02537  -0.00979 1878 HOH A O   
3330 O O   . HOH F .   ? 0.93063 0.48968 0.31480 -0.01366 0.02475  -0.01793 1879 HOH A O   
3331 O O   . HOH F .   ? 0.67305 0.53223 0.52919 -0.27617 0.16808  -0.24306 1880 HOH A O   
3333 O O   . HOH F .   ? 0.44341 0.66027 0.30166 0.22525  -0.13668 -0.08079 1882 HOH A O   
3335 O O   . HOH F .   ? 0.66846 0.89979 0.52901 -0.00662 -0.25424 0.17813  1884 HOH A O   
3336 O O   . HOH F .   ? 0.30735 0.31382 0.61536 -0.11371 -0.14229 0.18449  1885 HOH A O   
3337 O O   . HOH F .   ? 0.43951 0.68273 0.24407 0.19552  -0.02707 0.09248  1886 HOH A O   
3339 O O   . HOH F .   ? 0.74576 0.55685 0.70493 -0.03852 -0.25672 0.24091  1888 HOH A O   
3340 O O   . HOH F .   ? 0.57683 0.61563 0.70878 -0.15683 -0.33623 -0.01451 1889 HOH A O   
3341 O O   . HOH F .   ? 0.54324 0.47379 0.26791 -0.05369 0.08959  0.17138  1890 HOH A O   
3342 O O   . HOH F .   ? 0.29430 0.54810 0.45250 0.09627  0.03830  -0.05514 1891 HOH A O   
3347 O O   . HOH F .   ? 0.86535 0.50993 0.55809 0.14293  0.37094  0.10733  1896 HOH A O   
3348 O O   . HOH F .   ? 0.41830 0.36667 0.25794 -0.10594 0.00031  0.02058  1897 HOH A O   
3349 O O   . HOH F .   ? 0.44833 0.93172 0.50299 0.01823  0.13212  0.04778  1898 HOH A O   
3350 O O   . HOH F .   ? 0.29230 0.20615 0.45206 0.03543  -0.13594 -0.04960 1899 HOH A O   
3351 O O   . HOH F .   ? 0.29529 0.62272 0.29889 -0.12073 -0.12009 0.06216  1900 HOH A O   
3353 O O   . HOH F .   ? 0.33038 0.47452 0.48072 -0.07171 0.01634  0.05352  1902 HOH A O   
3354 O O   . HOH F .   ? 0.26910 0.39378 0.23838 -0.11144 0.06532  -0.09871 1903 HOH A O   
3357 O O   . HOH F .   ? 0.60048 1.05484 0.29201 0.18609  -0.01096 -0.07117 1906 HOH A O   
3359 O O   . HOH F .   ? 0.70043 0.62612 0.64246 -0.19042 0.11960  0.23414  1908 HOH A O   
3360 O O   . HOH F .   ? 0.87955 0.80157 0.25865 0.11530  0.05423  -0.02032 1909 HOH A O   
3362 O O   . HOH F .   ? 0.65495 0.51478 0.85041 -0.21437 -0.40221 0.20636  1911 HOH A O   
3364 O O   . HOH F .   ? 0.56187 0.55973 0.46233 -0.07249 -0.06033 0.07524  1913 HOH A O   
3366 O O   . HOH F .   ? 1.25517 0.60754 0.56129 -0.06481 0.38943  0.05511  1915 HOH A O   
3367 O O   . HOH F .   ? 0.51577 0.54365 0.27400 -0.26867 -0.06660 -0.01674 1916 HOH A O   
3368 O O   . HOH F .   ? 0.72105 0.55752 0.76847 0.29079  -0.16394 -0.13887 1917 HOH A O   
3369 O O   . HOH F .   ? 0.70736 0.31496 0.48344 -0.04541 -0.17083 0.01165  1918 HOH A O   
3370 O O   . HOH F .   ? 0.21150 0.56225 0.37275 -0.04281 -0.02838 -0.16092 1919 HOH A O   
3371 O O   . HOH F .   ? 0.74462 0.60397 0.66729 -0.13676 -0.11995 0.16665  1920 HOH A O   
3374 O O   . HOH F .   ? 0.58715 0.91909 0.40601 -0.35967 -0.03977 -0.10007 1923 HOH A O   
3375 O O   . HOH F .   ? 0.43691 0.31481 0.23578 0.01144  0.01887  0.00910  1924 HOH A O   
3376 O O   . HOH F .   ? 0.49466 0.83750 0.80082 0.08387  -0.31164 -0.12572 1925 HOH A O   
3377 O O   . HOH F .   ? 0.45485 0.91109 0.36757 -0.03332 -0.13086 -0.07545 1926 HOH A O   
3378 O O   . HOH F .   ? 0.38099 0.34101 0.22087 -0.09352 0.05934  -0.06330 1927 HOH A O   
3379 O O   . HOH F .   ? 0.15533 0.22004 0.09044 -0.01014 0.01628  0.02993  1928 HOH A O   
3380 O O   . HOH F .   ? 0.19018 0.62393 0.25039 -0.04136 -0.01640 0.18264  1929 HOH A O   
3381 O O   . HOH F .   ? 0.73240 0.59197 0.47918 0.32536  -0.21142 -0.04609 1930 HOH A O   
3382 O O   . HOH F .   ? 0.44646 0.30763 0.15131 -0.05869 -0.08465 0.01958  1931 HOH A O   
3383 O O   . HOH F .   ? 0.35976 0.81563 0.26705 0.09831  -0.07867 -0.11659 1932 HOH A O   
3384 O O   . HOH F .   ? 0.21877 0.33643 0.11461 -0.03289 0.00867  0.02404  1933 HOH A O   
3385 O O   . HOH F .   ? 0.70011 0.47425 0.74896 -0.14060 0.18799  0.07786  1934 HOH A O   
3387 O O   . HOH F .   ? 0.50193 0.58483 0.59052 0.05864  -0.12954 -0.29197 1936 HOH A O   
3389 O O   . HOH F .   ? 0.38327 0.41297 0.16839 -0.01718 0.03346  0.00713  1938 HOH A O   
3390 O O   . HOH F .   ? 0.34646 0.60624 0.54993 0.19506  -0.07200 -0.25243 1939 HOH A O   
3395 O O   . HOH F .   ? 0.22162 0.57857 0.33940 0.15586  -0.02535 -0.06104 1944 HOH A O   
3397 O O   . HOH F .   ? 0.59532 0.40633 0.53496 0.20232  -0.12281 -0.14170 1946 HOH A O   
3398 O O   . HOH F .   ? 0.54987 0.90658 0.68407 -0.01776 0.32079  0.17256  1947 HOH A O   
3400 O O   . HOH F .   ? 0.29798 0.30663 0.60974 -0.06263 0.05663  0.17596  1949 HOH A O   
3401 O O   . HOH F .   ? 0.44889 0.53432 0.26602 -0.03722 -0.07624 0.03501  1950 HOH A O   
3403 O O   . HOH F .   ? 0.50077 0.35043 0.32822 0.23278  0.07417  0.05603  1952 HOH A O   
3404 O O   . HOH F .   ? 0.30113 0.36107 0.18663 0.00150  -0.00080 0.02071  1953 HOH A O   
3405 O O   . HOH F .   ? 0.51865 0.75627 0.75610 0.13302  0.32061  0.15656  1954 HOH A O   
3406 O O   . HOH F .   ? 0.76948 0.57465 0.43372 0.27143  0.13194  0.14909  1955 HOH A O   
3407 O O   . HOH F .   ? 0.57874 0.55111 0.43970 0.28106  0.08612  0.02846  1956 HOH A O   
3410 O O   . HOH F .   ? 0.51525 0.53066 0.29118 0.07690  -0.07367 0.05555  1959 HOH A O   
3411 O O   . HOH F .   ? 0.60745 0.46225 0.64415 -0.05820 -0.30717 0.19018  1960 HOH A O   
3412 O O   A HOH F .   ? 0.36435 0.28873 0.46578 -0.09652 0.20557  -0.15055 1961 HOH A O   
3413 O O   B HOH F .   ? 0.19667 0.49605 0.51418 -0.13676 -0.01596 0.03394  1961 HOH A O   
3414 O O   . HOH F .   ? 0.78855 0.70503 0.71908 -0.13758 0.32598  -0.23666 1962 HOH A O   
3415 O O   . HOH F .   ? 0.33415 0.23851 0.67242 0.02613  0.00487  -0.14098 1963 HOH A O   
3419 O O   . HOH F .   ? 0.41709 0.72782 0.63631 0.12671  -0.24509 0.11385  1967 HOH A O   
3420 O O   . HOH F .   ? 0.35544 0.57362 0.68181 -0.09347 0.24822  -0.07682 1968 HOH A O   
3421 O O   . HOH F .   ? 0.49178 0.36990 0.65834 -0.08014 0.20554  -0.03433 1969 HOH A O   
3423 O O   . HOH F .   ? 0.31285 0.45355 1.02914 0.08734  -0.03470 0.10884  1971 HOH A O   
3424 O O   . HOH F .   ? 0.39537 0.51036 0.71199 -0.09463 -0.11170 -0.10014 1972 HOH A O   
3425 O O   . HOH F .   ? 0.43488 0.97844 0.36346 -0.32147 -0.03452 0.04093  1973 HOH A O   
3426 O O   . HOH F .   ? 0.54458 0.77209 0.68334 -0.07851 -0.20183 0.00979  1974 HOH A O   
3427 O O   . HOH F .   ? 0.34420 0.27872 0.39097 0.04174  0.08297  0.02096  1975 HOH A O   
3428 O O   . HOH F .   ? 0.71954 0.96376 0.60673 0.13030  0.33112  -0.15296 1976 HOH A O   
3429 O O   . HOH F .   ? 0.55981 0.34075 0.72914 0.05409  0.25656  0.06256  1977 HOH A O   
3430 O O   . HOH F .   ? 0.29997 0.55049 0.25659 0.05397  -0.10913 -0.10842 1978 HOH A O   
3433 O O   . HOH F .   ? 0.35639 0.31036 0.46109 0.09057  0.15188  -0.03956 1981 HOH A O   
3434 O O   . HOH F .   ? 0.43757 0.32430 0.94010 0.00644  0.03352  -0.01499 1982 HOH A O   
3435 O O   . HOH F .   ? 0.17281 0.24411 0.20009 -0.01222 -0.00187 -0.00833 1983 HOH A O   
3436 O O   . HOH F .   ? 0.53773 0.44788 0.40754 -0.16048 0.19565  -0.20793 1984 HOH A O   
3437 O O   . HOH F .   ? 0.33610 0.43680 0.20941 0.07558  -0.05630 -0.10404 1985 HOH A O   
3438 O O   . HOH F .   ? 1.03700 0.62006 0.52703 -0.11926 0.30281  -0.10511 1986 HOH A O   
3440 O O   . HOH F .   ? 0.91654 0.59732 0.36868 0.18779  0.20158  0.10350  1988 HOH A O   
3441 O O   . HOH F .   ? 0.62827 0.75373 0.48867 -0.06827 0.10987  0.31090  1989 HOH A O   
3442 O O   . HOH F .   ? 0.43327 0.60154 0.19609 0.16659  -0.06584 -0.04633 1990 HOH A O   
3443 O O   . HOH F .   ? 0.31382 0.48935 0.27664 -0.12231 -0.03061 -0.09118 1991 HOH A O   
3444 O O   . HOH F .   ? 0.64902 0.31968 0.35156 -0.16206 -0.00726 -0.00563 1992 HOH A O   
3448 O O   . HOH F .   ? 0.52987 0.29839 0.21985 -0.14503 0.14326  -0.05411 1996 HOH A O   
3449 O O   . HOH F .   ? 0.24158 0.34383 0.29940 0.00944  -0.00964 -0.02729 1997 HOH A O   
3450 O O   . HOH F .   ? 0.44961 0.38870 0.32132 0.04695  -0.10491 -0.11638 1998 HOH A O   
3451 O O   . HOH F .   ? 0.17062 0.51069 0.38036 -0.05909 0.01297  0.14581  1999 HOH A O   
3452 O O   . HOH F .   ? 0.46487 0.60569 0.42756 -0.20228 0.08632  -0.14826 2000 HOH A O   
3453 O O   . HOH F .   ? 0.71620 0.46147 0.28622 -0.21243 -0.17461 0.07632  2001 HOH A O   
3454 O O   . HOH F .   ? 0.40223 0.49957 0.30258 0.09813  0.01368  -0.05549 2002 HOH A O   
3455 O O   . HOH F .   ? 0.45734 0.40111 0.17910 -0.17234 0.05063  -0.02659 2003 HOH A O   
3456 O O   . HOH F .   ? 0.28420 0.25678 0.14753 -0.10163 -0.05988 0.01361  2004 HOH A O   
3457 O O   . HOH F .   ? 0.47111 0.34960 0.59634 -0.10307 0.00380  0.10496  2005 HOH A O   
3458 O O   . HOH F .   ? 0.69564 0.70479 0.62293 -0.19852 -0.05538 -0.17798 2006 HOH A O   
3459 O O   . HOH F .   ? 0.53236 1.04665 0.40524 0.16439  0.14617  -0.08505 2007 HOH A O   
3462 O O   . HOH F .   ? 0.29981 0.71863 0.26098 0.00876  -0.05584 0.14435  2010 HOH A O   
# 
