data_9KKC
# 
_entry.id   9KKC 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9KKC         pdb_00009kkc 10.2210/pdb9kkc/pdb 
WWPDB D_1300053676 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-01-29 ? 
2 'Structure model' 1 1 2025-02-19 ? 
3 'Structure model' 1 2 2025-03-12 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Database references' 
2 3 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 3 'Structure model' citation        
4 3 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.pdbx_database_id_DOI'    
2 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
3 2 'Structure model' '_citation.title'                   
4 2 'Structure model' '_citation_author.identifier_ORCID' 
5 3 'Structure model' '_citation.journal_volume'          
6 3 'Structure model' '_citation.page_first'              
7 3 'Structure model' '_citation.page_last'               
8 3 'Structure model' '_citation_author.identifier_ORCID' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9KKC 
_pdbx_database_status.recvd_initial_deposition_date   2024-11-13 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              gkurisu@protein.osaka-u.ac.jp 
_pdbx_contact_author.name_first         Genji 
_pdbx_contact_author.name_last          Kurisu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-5354-0807 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Uenaka, M.'  1 0009-0000-4663-7582 
'Ohnishi, Y.' 2 0000-0002-1378-054X 
'Tanaka, H.'  3 0000-0003-2035-954X 
'Kurisu, G.'  4 0000-0002-5354-0807 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Acta Crystallogr.,Sect.F' 
_citation.journal_id_ASTM           ACSFEN 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2053-230X 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            81 
_citation.language                  ? 
_citation.page_first                73 
_citation.page_last                 84 
_citation.title                     
;Redox-dependent hydrogen-bond network rearrangement of ferredoxin-NADP + reductase revealed by high-resolution X-ray and neutron crystallography.
;
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1107/S2053230X25000524 
_citation.pdbx_database_id_PubMed   39913263 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Uenaka, M.'  1 ? 
primary 'Ohnishi, Y.' 2 ? 
primary 'Ise, A.'     3 ? 
primary 'Yu, J.'      4 ? 
primary 'Yano, N.'    5 ? 
primary 'Kusaka, K.'  6 ? 
primary 'Tanaka, H.'  7 ? 
primary 'Kurisu, G.'  8 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Ferredoxin--NADP reductase, chloroplastic' 34604.191 1   1.18.1.2 ? 'UNP residues 17-327' ? 
2 non-polymer syn 'FLAVIN-ADENINE DINUCLEOTIDE'               785.550   1   ?        ? ?                     ? 
3 non-polymer syn '2-(N-MORPHOLINO)-ETHANESULFONIC ACID'      195.237   1   ?        ? ?                     ? 
4 water       nat water                                       18.015    447 ?        ? ?                     ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        FNR 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;SKVSVAPLHLESAKEPPLNTYKPKEPFTATIVSVESLVGPKAPGETCHIVIDHGGNVPYWEGQSYGVIPPGENPKKPGAP
QNVRLYSIASTRYGDNFDGRTGSLCVRRAVYYDPETGKEDPSKNGVCSNFLCNSKPGDKIQLTGPSGKIMLLPEEDPNAT
HIMIATGTGVAPFRGYLRRMFMEDVPNYRFGGLAWLFLGVANSDSLLYDEEFTSYLKQYPDNFRYDKALSREQKNRSGGK
MYVQDKIEEYSDEIFKLLDGGAHIYFCGLKGMMPGIQDTLKKVAERRGESWDQKLAQLKKNKQWHVEVY
;
_entity_poly.pdbx_seq_one_letter_code_can   
;SKVSVAPLHLESAKEPPLNTYKPKEPFTATIVSVESLVGPKAPGETCHIVIDHGGNVPYWEGQSYGVIPPGENPKKPGAP
QNVRLYSIASTRYGDNFDGRTGSLCVRRAVYYDPETGKEDPSKNGVCSNFLCNSKPGDKIQLTGPSGKIMLLPEEDPNAT
HIMIATGTGVAPFRGYLRRMFMEDVPNYRFGGLAWLFLGVANSDSLLYDEEFTSYLKQYPDNFRYDKALSREQKNRSGGK
MYVQDKIEEYSDEIFKLLDGGAHIYFCGLKGMMPGIQDTLKKVAERRGESWDQKLAQLKKNKQWHVEVY
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'FLAVIN-ADENINE DINUCLEOTIDE'          FAD 
3 '2-(N-MORPHOLINO)-ETHANESULFONIC ACID' MES 
4 water                                  HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER n 
1 2   LYS n 
1 3   VAL n 
1 4   SER n 
1 5   VAL n 
1 6   ALA n 
1 7   PRO n 
1 8   LEU n 
1 9   HIS n 
1 10  LEU n 
1 11  GLU n 
1 12  SER n 
1 13  ALA n 
1 14  LYS n 
1 15  GLU n 
1 16  PRO n 
1 17  PRO n 
1 18  LEU n 
1 19  ASN n 
1 20  THR n 
1 21  TYR n 
1 22  LYS n 
1 23  PRO n 
1 24  LYS n 
1 25  GLU n 
1 26  PRO n 
1 27  PHE n 
1 28  THR n 
1 29  ALA n 
1 30  THR n 
1 31  ILE n 
1 32  VAL n 
1 33  SER n 
1 34  VAL n 
1 35  GLU n 
1 36  SER n 
1 37  LEU n 
1 38  VAL n 
1 39  GLY n 
1 40  PRO n 
1 41  LYS n 
1 42  ALA n 
1 43  PRO n 
1 44  GLY n 
1 45  GLU n 
1 46  THR n 
1 47  CYS n 
1 48  HIS n 
1 49  ILE n 
1 50  VAL n 
1 51  ILE n 
1 52  ASP n 
1 53  HIS n 
1 54  GLY n 
1 55  GLY n 
1 56  ASN n 
1 57  VAL n 
1 58  PRO n 
1 59  TYR n 
1 60  TRP n 
1 61  GLU n 
1 62  GLY n 
1 63  GLN n 
1 64  SER n 
1 65  TYR n 
1 66  GLY n 
1 67  VAL n 
1 68  ILE n 
1 69  PRO n 
1 70  PRO n 
1 71  GLY n 
1 72  GLU n 
1 73  ASN n 
1 74  PRO n 
1 75  LYS n 
1 76  LYS n 
1 77  PRO n 
1 78  GLY n 
1 79  ALA n 
1 80  PRO n 
1 81  GLN n 
1 82  ASN n 
1 83  VAL n 
1 84  ARG n 
1 85  LEU n 
1 86  TYR n 
1 87  SER n 
1 88  ILE n 
1 89  ALA n 
1 90  SER n 
1 91  THR n 
1 92  ARG n 
1 93  TYR n 
1 94  GLY n 
1 95  ASP n 
1 96  ASN n 
1 97  PHE n 
1 98  ASP n 
1 99  GLY n 
1 100 ARG n 
1 101 THR n 
1 102 GLY n 
1 103 SER n 
1 104 LEU n 
1 105 CYS n 
1 106 VAL n 
1 107 ARG n 
1 108 ARG n 
1 109 ALA n 
1 110 VAL n 
1 111 TYR n 
1 112 TYR n 
1 113 ASP n 
1 114 PRO n 
1 115 GLU n 
1 116 THR n 
1 117 GLY n 
1 118 LYS n 
1 119 GLU n 
1 120 ASP n 
1 121 PRO n 
1 122 SER n 
1 123 LYS n 
1 124 ASN n 
1 125 GLY n 
1 126 VAL n 
1 127 CYS n 
1 128 SER n 
1 129 ASN n 
1 130 PHE n 
1 131 LEU n 
1 132 CYS n 
1 133 ASN n 
1 134 SER n 
1 135 LYS n 
1 136 PRO n 
1 137 GLY n 
1 138 ASP n 
1 139 LYS n 
1 140 ILE n 
1 141 GLN n 
1 142 LEU n 
1 143 THR n 
1 144 GLY n 
1 145 PRO n 
1 146 SER n 
1 147 GLY n 
1 148 LYS n 
1 149 ILE n 
1 150 MET n 
1 151 LEU n 
1 152 LEU n 
1 153 PRO n 
1 154 GLU n 
1 155 GLU n 
1 156 ASP n 
1 157 PRO n 
1 158 ASN n 
1 159 ALA n 
1 160 THR n 
1 161 HIS n 
1 162 ILE n 
1 163 MET n 
1 164 ILE n 
1 165 ALA n 
1 166 THR n 
1 167 GLY n 
1 168 THR n 
1 169 GLY n 
1 170 VAL n 
1 171 ALA n 
1 172 PRO n 
1 173 PHE n 
1 174 ARG n 
1 175 GLY n 
1 176 TYR n 
1 177 LEU n 
1 178 ARG n 
1 179 ARG n 
1 180 MET n 
1 181 PHE n 
1 182 MET n 
1 183 GLU n 
1 184 ASP n 
1 185 VAL n 
1 186 PRO n 
1 187 ASN n 
1 188 TYR n 
1 189 ARG n 
1 190 PHE n 
1 191 GLY n 
1 192 GLY n 
1 193 LEU n 
1 194 ALA n 
1 195 TRP n 
1 196 LEU n 
1 197 PHE n 
1 198 LEU n 
1 199 GLY n 
1 200 VAL n 
1 201 ALA n 
1 202 ASN n 
1 203 SER n 
1 204 ASP n 
1 205 SER n 
1 206 LEU n 
1 207 LEU n 
1 208 TYR n 
1 209 ASP n 
1 210 GLU n 
1 211 GLU n 
1 212 PHE n 
1 213 THR n 
1 214 SER n 
1 215 TYR n 
1 216 LEU n 
1 217 LYS n 
1 218 GLN n 
1 219 TYR n 
1 220 PRO n 
1 221 ASP n 
1 222 ASN n 
1 223 PHE n 
1 224 ARG n 
1 225 TYR n 
1 226 ASP n 
1 227 LYS n 
1 228 ALA n 
1 229 LEU n 
1 230 SER n 
1 231 ARG n 
1 232 GLU n 
1 233 GLN n 
1 234 LYS n 
1 235 ASN n 
1 236 ARG n 
1 237 SER n 
1 238 GLY n 
1 239 GLY n 
1 240 LYS n 
1 241 MET n 
1 242 TYR n 
1 243 VAL n 
1 244 GLN n 
1 245 ASP n 
1 246 LYS n 
1 247 ILE n 
1 248 GLU n 
1 249 GLU n 
1 250 TYR n 
1 251 SER n 
1 252 ASP n 
1 253 GLU n 
1 254 ILE n 
1 255 PHE n 
1 256 LYS n 
1 257 LEU n 
1 258 LEU n 
1 259 ASP n 
1 260 GLY n 
1 261 GLY n 
1 262 ALA n 
1 263 HIS n 
1 264 ILE n 
1 265 TYR n 
1 266 PHE n 
1 267 CYS n 
1 268 GLY n 
1 269 LEU n 
1 270 LYS n 
1 271 GLY n 
1 272 MET n 
1 273 MET n 
1 274 PRO n 
1 275 GLY n 
1 276 ILE n 
1 277 GLN n 
1 278 ASP n 
1 279 THR n 
1 280 LEU n 
1 281 LYS n 
1 282 LYS n 
1 283 VAL n 
1 284 ALA n 
1 285 GLU n 
1 286 ARG n 
1 287 ARG n 
1 288 GLY n 
1 289 GLU n 
1 290 SER n 
1 291 TRP n 
1 292 ASP n 
1 293 GLN n 
1 294 LYS n 
1 295 LEU n 
1 296 ALA n 
1 297 GLN n 
1 298 LEU n 
1 299 LYS n 
1 300 LYS n 
1 301 ASN n 
1 302 LYS n 
1 303 GLN n 
1 304 TRP n 
1 305 HIS n 
1 306 VAL n 
1 307 GLU n 
1 308 VAL n 
1 309 TYR n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   309 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 '542713, ZEAMMB73_Zm00001d034345' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Zea mays' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     4577 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                ? 'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                               ? 'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                             ? 'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                        ? 'C4 H7 N O4'        133.103 
CYS 'L-peptide linking' y CYSTEINE                               ? 'C3 H7 N O2 S'      121.158 
FAD non-polymer         . 'FLAVIN-ADENINE DINUCLEOTIDE'          ? 'C27 H33 N9 O15 P2' 785.550 
GLN 'L-peptide linking' y GLUTAMINE                              ? 'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                        ? 'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                                ? 'C2 H5 N O2'        75.067  
HIS 'L-peptide linking' y HISTIDINE                              ? 'C6 H10 N3 O2 1'    156.162 
HOH non-polymer         . WATER                                  ? 'H2 O'              18.015  
ILE 'L-peptide linking' y ISOLEUCINE                             ? 'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                                ? 'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                                 ? 'C6 H15 N2 O2 1'    147.195 
MES non-polymer         . '2-(N-MORPHOLINO)-ETHANESULFONIC ACID' ? 'C6 H13 N O4 S'     195.237 
MET 'L-peptide linking' y METHIONINE                             ? 'C5 H11 N O2 S'     149.211 
PHE 'L-peptide linking' y PHENYLALANINE                          ? 'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                                ? 'C5 H9 N O2'        115.130 
SER 'L-peptide linking' y SERINE                                 ? 'C3 H7 N O3'        105.093 
THR 'L-peptide linking' y THREONINE                              ? 'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                             ? 'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                               ? 'C9 H11 N O3'       181.189 
VAL 'L-peptide linking' y VALINE                                 ? 'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER 1   1009 1009 SER SER A . n 
A 1 2   LYS 2   1010 1010 LYS LYS A . n 
A 1 3   VAL 3   1011 1011 VAL VAL A . n 
A 1 4   SER 4   1012 1012 SER SER A . n 
A 1 5   VAL 5   1013 1013 VAL VAL A . n 
A 1 6   ALA 6   1014 1014 ALA ALA A . n 
A 1 7   PRO 7   1015 1015 PRO PRO A . n 
A 1 8   LEU 8   1016 1016 LEU LEU A . n 
A 1 9   HIS 9   1017 1017 HIS HIS A . n 
A 1 10  LEU 10  1018 1018 LEU LEU A . n 
A 1 11  GLU 11  1019 1019 GLU GLU A . n 
A 1 12  SER 12  1020 1020 SER SER A . n 
A 1 13  ALA 13  1021 1021 ALA ALA A . n 
A 1 14  LYS 14  1022 1022 LYS LYS A . n 
A 1 15  GLU 15  1023 1023 GLU GLU A . n 
A 1 16  PRO 16  1024 1024 PRO PRO A . n 
A 1 17  PRO 17  1025 1025 PRO PRO A . n 
A 1 18  LEU 18  1026 1026 LEU LEU A . n 
A 1 19  ASN 19  1027 1027 ASN ASN A . n 
A 1 20  THR 20  1028 1028 THR THR A . n 
A 1 21  TYR 21  1029 1029 TYR TYR A . n 
A 1 22  LYS 22  1030 1030 LYS LYS A . n 
A 1 23  PRO 23  1031 1031 PRO PRO A . n 
A 1 24  LYS 24  1032 1032 LYS LYS A . n 
A 1 25  GLU 25  1033 1033 GLU GLU A . n 
A 1 26  PRO 26  1034 1034 PRO PRO A . n 
A 1 27  PHE 27  1035 1035 PHE PHE A . n 
A 1 28  THR 28  1036 1036 THR THR A . n 
A 1 29  ALA 29  1037 1037 ALA ALA A . n 
A 1 30  THR 30  1038 1038 THR THR A . n 
A 1 31  ILE 31  1039 1039 ILE ILE A . n 
A 1 32  VAL 32  1040 1040 VAL VAL A . n 
A 1 33  SER 33  1041 1041 SER SER A . n 
A 1 34  VAL 34  1042 1042 VAL VAL A . n 
A 1 35  GLU 35  1043 1043 GLU GLU A . n 
A 1 36  SER 36  1044 1044 SER SER A . n 
A 1 37  LEU 37  1045 1045 LEU LEU A . n 
A 1 38  VAL 38  1046 1046 VAL VAL A . n 
A 1 39  GLY 39  1047 1047 GLY GLY A . n 
A 1 40  PRO 40  1048 1048 PRO PRO A . n 
A 1 41  LYS 41  1049 1049 LYS LYS A . n 
A 1 42  ALA 42  1050 1050 ALA ALA A . n 
A 1 43  PRO 43  1051 1051 PRO PRO A . n 
A 1 44  GLY 44  1052 1052 GLY GLY A . n 
A 1 45  GLU 45  1053 1053 GLU GLU A . n 
A 1 46  THR 46  1054 1054 THR THR A . n 
A 1 47  CYS 47  1055 1055 CYS CYS A . n 
A 1 48  HIS 48  1056 1056 HIS HIS A . n 
A 1 49  ILE 49  1057 1057 ILE ILE A . n 
A 1 50  VAL 50  1058 1058 VAL VAL A . n 
A 1 51  ILE 51  1059 1059 ILE ILE A . n 
A 1 52  ASP 52  1060 1060 ASP ASP A . n 
A 1 53  HIS 53  1061 1061 HIS HIS A . n 
A 1 54  GLY 54  1062 1062 GLY GLY A . n 
A 1 55  GLY 55  1063 1063 GLY GLY A . n 
A 1 56  ASN 56  1064 1064 ASN ASN A . n 
A 1 57  VAL 57  1065 1065 VAL VAL A . n 
A 1 58  PRO 58  1066 1066 PRO PRO A . n 
A 1 59  TYR 59  1067 1067 TYR TYR A . n 
A 1 60  TRP 60  1068 1068 TRP TRP A . n 
A 1 61  GLU 61  1069 1069 GLU GLU A . n 
A 1 62  GLY 62  1070 1070 GLY GLY A . n 
A 1 63  GLN 63  1071 1071 GLN GLN A . n 
A 1 64  SER 64  1072 1072 SER SER A . n 
A 1 65  TYR 65  1073 1073 TYR TYR A . n 
A 1 66  GLY 66  1074 1074 GLY GLY A . n 
A 1 67  VAL 67  1075 1075 VAL VAL A . n 
A 1 68  ILE 68  1076 1076 ILE ILE A . n 
A 1 69  PRO 69  1077 1077 PRO PRO A . n 
A 1 70  PRO 70  1078 1078 PRO PRO A . n 
A 1 71  GLY 71  1079 1079 GLY GLY A . n 
A 1 72  GLU 72  1080 1080 GLU GLU A . n 
A 1 73  ASN 73  1081 1081 ASN ASN A . n 
A 1 74  PRO 74  1082 1082 PRO PRO A . n 
A 1 75  LYS 75  1083 1083 LYS LYS A . n 
A 1 76  LYS 76  1084 1084 LYS LYS A . n 
A 1 77  PRO 77  1085 1085 PRO PRO A . n 
A 1 78  GLY 78  1086 1086 GLY GLY A . n 
A 1 79  ALA 79  1087 1087 ALA ALA A . n 
A 1 80  PRO 80  1088 1088 PRO PRO A . n 
A 1 81  GLN 81  1089 1089 GLN GLN A . n 
A 1 82  ASN 82  1090 1090 ASN ASN A . n 
A 1 83  VAL 83  1091 1091 VAL VAL A . n 
A 1 84  ARG 84  1092 1092 ARG ARG A . n 
A 1 85  LEU 85  1093 1093 LEU LEU A . n 
A 1 86  TYR 86  1094 1094 TYR TYR A . n 
A 1 87  SER 87  1095 1095 SER SER A . n 
A 1 88  ILE 88  1096 1096 ILE ILE A . n 
A 1 89  ALA 89  1097 1097 ALA ALA A . n 
A 1 90  SER 90  1098 1098 SER SER A . n 
A 1 91  THR 91  1099 1099 THR THR A . n 
A 1 92  ARG 92  1100 1100 ARG ARG A . n 
A 1 93  TYR 93  1101 1101 TYR TYR A . n 
A 1 94  GLY 94  1102 1102 GLY GLY A . n 
A 1 95  ASP 95  1103 1103 ASP ASP A . n 
A 1 96  ASN 96  1104 1104 ASN ASN A . n 
A 1 97  PHE 97  1105 1105 PHE PHE A . n 
A 1 98  ASP 98  1106 1106 ASP ASP A . n 
A 1 99  GLY 99  1107 1107 GLY GLY A . n 
A 1 100 ARG 100 1108 1108 ARG ARG A . n 
A 1 101 THR 101 1109 1109 THR THR A . n 
A 1 102 GLY 102 1110 1110 GLY GLY A . n 
A 1 103 SER 103 1111 1111 SER SER A . n 
A 1 104 LEU 104 1112 1112 LEU LEU A . n 
A 1 105 CYS 105 1113 1113 CYS CYS A . n 
A 1 106 VAL 106 1114 1114 VAL VAL A . n 
A 1 107 ARG 107 1115 1115 ARG ARG A . n 
A 1 108 ARG 108 1116 1116 ARG ARG A . n 
A 1 109 ALA 109 1117 1117 ALA ALA A . n 
A 1 110 VAL 110 1118 1118 VAL VAL A . n 
A 1 111 TYR 111 1119 1119 TYR TYR A . n 
A 1 112 TYR 112 1120 1120 TYR TYR A . n 
A 1 113 ASP 113 1121 1121 ASP ASP A . n 
A 1 114 PRO 114 1122 1122 PRO PRO A . n 
A 1 115 GLU 115 1123 1123 GLU GLU A . n 
A 1 116 THR 116 1124 1124 THR THR A . n 
A 1 117 GLY 117 1125 1125 GLY GLY A . n 
A 1 118 LYS 118 1126 1126 LYS LYS A . n 
A 1 119 GLU 119 1127 1127 GLU GLU A . n 
A 1 120 ASP 120 1128 1128 ASP ASP A . n 
A 1 121 PRO 121 1129 1129 PRO PRO A . n 
A 1 122 SER 122 1130 1130 SER SER A . n 
A 1 123 LYS 123 1131 1131 LYS LYS A . n 
A 1 124 ASN 124 1132 1132 ASN ASN A . n 
A 1 125 GLY 125 1133 1133 GLY GLY A . n 
A 1 126 VAL 126 1134 1134 VAL VAL A . n 
A 1 127 CYS 127 1135 1135 CYS CYS A . n 
A 1 128 SER 128 1136 1136 SER SER A . n 
A 1 129 ASN 129 1137 1137 ASN ASN A . n 
A 1 130 PHE 130 1138 1138 PHE PHE A . n 
A 1 131 LEU 131 1139 1139 LEU LEU A . n 
A 1 132 CYS 132 1140 1140 CYS CYS A . n 
A 1 133 ASN 133 1141 1141 ASN ASN A . n 
A 1 134 SER 134 1142 1142 SER SER A . n 
A 1 135 LYS 135 1143 1143 LYS LYS A . n 
A 1 136 PRO 136 1144 1144 PRO PRO A . n 
A 1 137 GLY 137 1145 1145 GLY GLY A . n 
A 1 138 ASP 138 1146 1146 ASP ASP A . n 
A 1 139 LYS 139 1147 1147 LYS LYS A . n 
A 1 140 ILE 140 1148 1148 ILE ILE A . n 
A 1 141 GLN 141 1149 1149 GLN GLN A . n 
A 1 142 LEU 142 1150 1150 LEU LEU A . n 
A 1 143 THR 143 1151 1151 THR THR A . n 
A 1 144 GLY 144 1152 1152 GLY GLY A . n 
A 1 145 PRO 145 1153 1153 PRO PRO A . n 
A 1 146 SER 146 1154 1154 SER SER A . n 
A 1 147 GLY 147 1155 1155 GLY GLY A . n 
A 1 148 LYS 148 1156 1156 LYS LYS A . n 
A 1 149 ILE 149 1157 1157 ILE ILE A . n 
A 1 150 MET 150 1158 1158 MET MET A . n 
A 1 151 LEU 151 1159 1159 LEU LEU A . n 
A 1 152 LEU 152 1160 1160 LEU LEU A . n 
A 1 153 PRO 153 1161 1161 PRO PRO A . n 
A 1 154 GLU 154 1162 1162 GLU GLU A . n 
A 1 155 GLU 155 1163 1163 GLU GLU A . n 
A 1 156 ASP 156 1164 1164 ASP ASP A . n 
A 1 157 PRO 157 1165 1165 PRO PRO A . n 
A 1 158 ASN 158 1166 1166 ASN ASN A . n 
A 1 159 ALA 159 1167 1167 ALA ALA A . n 
A 1 160 THR 160 1168 1168 THR THR A . n 
A 1 161 HIS 161 1169 1169 HIS HIS A . n 
A 1 162 ILE 162 1170 1170 ILE ILE A . n 
A 1 163 MET 163 1171 1171 MET MET A . n 
A 1 164 ILE 164 1172 1172 ILE ILE A . n 
A 1 165 ALA 165 1173 1173 ALA ALA A . n 
A 1 166 THR 166 1174 1174 THR THR A . n 
A 1 167 GLY 167 1175 1175 GLY GLY A . n 
A 1 168 THR 168 1176 1176 THR THR A . n 
A 1 169 GLY 169 1177 1177 GLY GLY A . n 
A 1 170 VAL 170 1178 1178 VAL VAL A . n 
A 1 171 ALA 171 1179 1179 ALA ALA A . n 
A 1 172 PRO 172 1180 1180 PRO PRO A . n 
A 1 173 PHE 173 1181 1181 PHE PHE A . n 
A 1 174 ARG 174 1182 1182 ARG ARG A . n 
A 1 175 GLY 175 1183 1183 GLY GLY A . n 
A 1 176 TYR 176 1184 1184 TYR TYR A . n 
A 1 177 LEU 177 1185 1185 LEU LEU A . n 
A 1 178 ARG 178 1186 1186 ARG ARG A . n 
A 1 179 ARG 179 1187 1187 ARG ARG A . n 
A 1 180 MET 180 1188 1188 MET MET A . n 
A 1 181 PHE 181 1189 1189 PHE PHE A . n 
A 1 182 MET 182 1190 1190 MET MET A . n 
A 1 183 GLU 183 1191 1191 GLU GLU A . n 
A 1 184 ASP 184 1192 1192 ASP ASP A . n 
A 1 185 VAL 185 1193 1193 VAL VAL A . n 
A 1 186 PRO 186 1194 1194 PRO PRO A . n 
A 1 187 ASN 187 1195 1195 ASN ASN A . n 
A 1 188 TYR 188 1196 1196 TYR TYR A . n 
A 1 189 ARG 189 1197 1197 ARG ARG A . n 
A 1 190 PHE 190 1198 1198 PHE PHE A . n 
A 1 191 GLY 191 1199 1199 GLY GLY A . n 
A 1 192 GLY 192 1200 1200 GLY GLY A . n 
A 1 193 LEU 193 1201 1201 LEU LEU A . n 
A 1 194 ALA 194 1202 1202 ALA ALA A . n 
A 1 195 TRP 195 1203 1203 TRP TRP A . n 
A 1 196 LEU 196 1204 1204 LEU LEU A . n 
A 1 197 PHE 197 1205 1205 PHE PHE A . n 
A 1 198 LEU 198 1206 1206 LEU LEU A . n 
A 1 199 GLY 199 1207 1207 GLY GLY A . n 
A 1 200 VAL 200 1208 1208 VAL VAL A . n 
A 1 201 ALA 201 1209 1209 ALA ALA A . n 
A 1 202 ASN 202 1210 1210 ASN ASN A . n 
A 1 203 SER 203 1211 1211 SER SER A . n 
A 1 204 ASP 204 1212 1212 ASP ASP A . n 
A 1 205 SER 205 1213 1213 SER SER A . n 
A 1 206 LEU 206 1214 1214 LEU LEU A . n 
A 1 207 LEU 207 1215 1215 LEU LEU A . n 
A 1 208 TYR 208 1216 1216 TYR TYR A . n 
A 1 209 ASP 209 1217 1217 ASP ASP A . n 
A 1 210 GLU 210 1218 1218 GLU GLU A . n 
A 1 211 GLU 211 1219 1219 GLU GLU A . n 
A 1 212 PHE 212 1220 1220 PHE PHE A . n 
A 1 213 THR 213 1221 1221 THR THR A . n 
A 1 214 SER 214 1222 1222 SER SER A . n 
A 1 215 TYR 215 1223 1223 TYR TYR A . n 
A 1 216 LEU 216 1224 1224 LEU LEU A . n 
A 1 217 LYS 217 1225 1225 LYS LYS A . n 
A 1 218 GLN 218 1226 1226 GLN GLN A . n 
A 1 219 TYR 219 1227 1227 TYR TYR A . n 
A 1 220 PRO 220 1228 1228 PRO PRO A . n 
A 1 221 ASP 221 1229 1229 ASP ASP A . n 
A 1 222 ASN 222 1230 1230 ASN ASN A . n 
A 1 223 PHE 223 1231 1231 PHE PHE A . n 
A 1 224 ARG 224 1232 1232 ARG ARG A . n 
A 1 225 TYR 225 1233 1233 TYR TYR A . n 
A 1 226 ASP 226 1234 1234 ASP ASP A . n 
A 1 227 LYS 227 1235 1235 LYS LYS A . n 
A 1 228 ALA 228 1236 1236 ALA ALA A . n 
A 1 229 LEU 229 1237 1237 LEU LEU A . n 
A 1 230 SER 230 1238 1238 SER SER A . n 
A 1 231 ARG 231 1239 1239 ARG ARG A . n 
A 1 232 GLU 232 1240 1240 GLU GLU A . n 
A 1 233 GLN 233 1241 1241 GLN GLN A . n 
A 1 234 LYS 234 1242 1242 LYS LYS A . n 
A 1 235 ASN 235 1243 1243 ASN ASN A . n 
A 1 236 ARG 236 1244 1244 ARG ARG A . n 
A 1 237 SER 237 1245 1245 SER SER A . n 
A 1 238 GLY 238 1246 1246 GLY GLY A . n 
A 1 239 GLY 239 1247 1247 GLY GLY A . n 
A 1 240 LYS 240 1248 1248 LYS LYS A . n 
A 1 241 MET 241 1249 1249 MET MET A . n 
A 1 242 TYR 242 1250 1250 TYR TYR A . n 
A 1 243 VAL 243 1251 1251 VAL VAL A . n 
A 1 244 GLN 244 1252 1252 GLN GLN A . n 
A 1 245 ASP 245 1253 1253 ASP ASP A . n 
A 1 246 LYS 246 1254 1254 LYS LYS A . n 
A 1 247 ILE 247 1255 1255 ILE ILE A . n 
A 1 248 GLU 248 1256 1256 GLU GLU A . n 
A 1 249 GLU 249 1257 1257 GLU GLU A . n 
A 1 250 TYR 250 1258 1258 TYR TYR A . n 
A 1 251 SER 251 1259 1259 SER SER A . n 
A 1 252 ASP 252 1260 1260 ASP ASP A . n 
A 1 253 GLU 253 1261 1261 GLU GLU A . n 
A 1 254 ILE 254 1262 1262 ILE ILE A . n 
A 1 255 PHE 255 1263 1263 PHE PHE A . n 
A 1 256 LYS 256 1264 1264 LYS LYS A . n 
A 1 257 LEU 257 1265 1265 LEU LEU A . n 
A 1 258 LEU 258 1266 1266 LEU LEU A . n 
A 1 259 ASP 259 1267 1267 ASP ASP A . n 
A 1 260 GLY 260 1268 1268 GLY GLY A . n 
A 1 261 GLY 261 1269 1269 GLY GLY A . n 
A 1 262 ALA 262 1270 1270 ALA ALA A . n 
A 1 263 HIS 263 1271 1271 HIS HIS A . n 
A 1 264 ILE 264 1272 1272 ILE ILE A . n 
A 1 265 TYR 265 1273 1273 TYR TYR A . n 
A 1 266 PHE 266 1274 1274 PHE PHE A . n 
A 1 267 CYS 267 1275 1275 CYS CYS A . n 
A 1 268 GLY 268 1276 1276 GLY GLY A . n 
A 1 269 LEU 269 1277 1277 LEU LEU A . n 
A 1 270 LYS 270 1278 1278 LYS LYS A . n 
A 1 271 GLY 271 1279 1279 GLY GLY A . n 
A 1 272 MET 272 1280 1280 MET MET A . n 
A 1 273 MET 273 1281 1281 MET MET A . n 
A 1 274 PRO 274 1282 1282 PRO PRO A . n 
A 1 275 GLY 275 1283 1283 GLY GLY A . n 
A 1 276 ILE 276 1284 1284 ILE ILE A . n 
A 1 277 GLN 277 1285 1285 GLN GLN A . n 
A 1 278 ASP 278 1286 1286 ASP ASP A . n 
A 1 279 THR 279 1287 1287 THR THR A . n 
A 1 280 LEU 280 1288 1288 LEU LEU A . n 
A 1 281 LYS 281 1289 1289 LYS LYS A . n 
A 1 282 LYS 282 1290 1290 LYS LYS A . n 
A 1 283 VAL 283 1291 1291 VAL VAL A . n 
A 1 284 ALA 284 1292 1292 ALA ALA A . n 
A 1 285 GLU 285 1293 1293 GLU GLU A . n 
A 1 286 ARG 286 1294 1294 ARG ARG A . n 
A 1 287 ARG 287 1295 1295 ARG ARG A . n 
A 1 288 GLY 288 1296 1296 GLY GLY A . n 
A 1 289 GLU 289 1297 1297 GLU GLU A . n 
A 1 290 SER 290 1298 1298 SER SER A . n 
A 1 291 TRP 291 1299 1299 TRP TRP A . n 
A 1 292 ASP 292 1300 1300 ASP ASP A . n 
A 1 293 GLN 293 1301 1301 GLN GLN A . n 
A 1 294 LYS 294 1302 1302 LYS LYS A . n 
A 1 295 LEU 295 1303 1303 LEU LEU A . n 
A 1 296 ALA 296 1304 1304 ALA ALA A . n 
A 1 297 GLN 297 1305 1305 GLN GLN A . n 
A 1 298 LEU 298 1306 1306 LEU LEU A . n 
A 1 299 LYS 299 1307 1307 LYS LYS A . n 
A 1 300 LYS 300 1308 1308 LYS LYS A . n 
A 1 301 ASN 301 1309 1309 ASN ASN A . n 
A 1 302 LYS 302 1310 1310 LYS LYS A . n 
A 1 303 GLN 303 1311 1311 GLN GLN A . n 
A 1 304 TRP 304 1312 1312 TRP TRP A . n 
A 1 305 HIS 305 1313 1313 HIS HIS A . n 
A 1 306 VAL 306 1314 1314 VAL VAL A . n 
A 1 307 GLU 307 1315 1315 GLU GLU A . n 
A 1 308 VAL 308 1316 1316 VAL VAL A . n 
A 1 309 TYR 309 1317 1317 TYR TYR A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        FAD 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   FAD 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 FAD 1   1401 1401 FAD FAD A . 
C 3 MES 1   1402 1402 MES MES A . 
D 4 HOH 1   1501 203  HOH HOH A . 
D 4 HOH 2   1502 284  HOH HOH A . 
D 4 HOH 3   1503 190  HOH HOH A . 
D 4 HOH 4   1504 354  HOH HOH A . 
D 4 HOH 5   1505 119  HOH HOH A . 
D 4 HOH 6   1506 214  HOH HOH A . 
D 4 HOH 7   1507 64   HOH HOH A . 
D 4 HOH 8   1508 283  HOH HOH A . 
D 4 HOH 9   1509 33   HOH HOH A . 
D 4 HOH 10  1510 267  HOH HOH A . 
D 4 HOH 11  1511 183  HOH HOH A . 
D 4 HOH 12  1512 158  HOH HOH A . 
D 4 HOH 13  1513 89   HOH HOH A . 
D 4 HOH 14  1514 607  HOH HOH A . 
D 4 HOH 15  1515 54   HOH HOH A . 
D 4 HOH 16  1516 52   HOH HOH A . 
D 4 HOH 17  1517 58   HOH HOH A . 
D 4 HOH 18  1518 139  HOH HOH A . 
D 4 HOH 19  1519 179  HOH HOH A . 
D 4 HOH 20  1520 428  HOH HOH A . 
D 4 HOH 21  1521 481  HOH HOH A . 
D 4 HOH 22  1522 148  HOH HOH A . 
D 4 HOH 23  1523 253  HOH HOH A . 
D 4 HOH 24  1524 619  HOH HOH A . 
D 4 HOH 25  1525 507  HOH HOH A . 
D 4 HOH 26  1526 82   HOH HOH A . 
D 4 HOH 27  1527 588  HOH HOH A . 
D 4 HOH 28  1528 96   HOH HOH A . 
D 4 HOH 29  1529 612  HOH HOH A . 
D 4 HOH 30  1530 81   HOH HOH A . 
D 4 HOH 31  1531 263  HOH HOH A . 
D 4 HOH 32  1532 116  HOH HOH A . 
D 4 HOH 33  1533 124  HOH HOH A . 
D 4 HOH 34  1534 326  HOH HOH A . 
D 4 HOH 35  1535 157  HOH HOH A . 
D 4 HOH 36  1536 384  HOH HOH A . 
D 4 HOH 37  1537 135  HOH HOH A . 
D 4 HOH 38  1538 71   HOH HOH A . 
D 4 HOH 39  1539 553  HOH HOH A . 
D 4 HOH 40  1540 446  HOH HOH A . 
D 4 HOH 41  1541 110  HOH HOH A . 
D 4 HOH 42  1542 604  HOH HOH A . 
D 4 HOH 43  1543 23   HOH HOH A . 
D 4 HOH 44  1544 15   HOH HOH A . 
D 4 HOH 45  1545 297  HOH HOH A . 
D 4 HOH 46  1546 20   HOH HOH A . 
D 4 HOH 47  1547 19   HOH HOH A . 
D 4 HOH 48  1548 423  HOH HOH A . 
D 4 HOH 49  1549 378  HOH HOH A . 
D 4 HOH 50  1550 289  HOH HOH A . 
D 4 HOH 51  1551 261  HOH HOH A . 
D 4 HOH 52  1552 352  HOH HOH A . 
D 4 HOH 53  1553 22   HOH HOH A . 
D 4 HOH 54  1554 252  HOH HOH A . 
D 4 HOH 55  1555 72   HOH HOH A . 
D 4 HOH 56  1556 232  HOH HOH A . 
D 4 HOH 57  1557 3    HOH HOH A . 
D 4 HOH 58  1558 100  HOH HOH A . 
D 4 HOH 59  1559 176  HOH HOH A . 
D 4 HOH 60  1560 70   HOH HOH A . 
D 4 HOH 61  1561 599  HOH HOH A . 
D 4 HOH 62  1562 69   HOH HOH A . 
D 4 HOH 63  1563 181  HOH HOH A . 
D 4 HOH 64  1564 453  HOH HOH A . 
D 4 HOH 65  1565 527  HOH HOH A . 
D 4 HOH 66  1566 600  HOH HOH A . 
D 4 HOH 67  1567 168  HOH HOH A . 
D 4 HOH 68  1568 236  HOH HOH A . 
D 4 HOH 69  1569 123  HOH HOH A . 
D 4 HOH 70  1570 204  HOH HOH A . 
D 4 HOH 71  1571 338  HOH HOH A . 
D 4 HOH 72  1572 18   HOH HOH A . 
D 4 HOH 73  1573 554  HOH HOH A . 
D 4 HOH 74  1574 266  HOH HOH A . 
D 4 HOH 75  1575 27   HOH HOH A . 
D 4 HOH 76  1576 80   HOH HOH A . 
D 4 HOH 77  1577 31   HOH HOH A . 
D 4 HOH 78  1578 142  HOH HOH A . 
D 4 HOH 79  1579 218  HOH HOH A . 
D 4 HOH 80  1580 21   HOH HOH A . 
D 4 HOH 81  1581 35   HOH HOH A . 
D 4 HOH 82  1582 67   HOH HOH A . 
D 4 HOH 83  1583 1    HOH HOH A . 
D 4 HOH 84  1584 108  HOH HOH A . 
D 4 HOH 85  1585 256  HOH HOH A . 
D 4 HOH 86  1586 95   HOH HOH A . 
D 4 HOH 87  1587 248  HOH HOH A . 
D 4 HOH 88  1588 197  HOH HOH A . 
D 4 HOH 89  1589 474  HOH HOH A . 
D 4 HOH 90  1590 436  HOH HOH A . 
D 4 HOH 91  1591 380  HOH HOH A . 
D 4 HOH 92  1592 171  HOH HOH A . 
D 4 HOH 93  1593 473  HOH HOH A . 
D 4 HOH 94  1594 221  HOH HOH A . 
D 4 HOH 95  1595 294  HOH HOH A . 
D 4 HOH 96  1596 313  HOH HOH A . 
D 4 HOH 97  1597 30   HOH HOH A . 
D 4 HOH 98  1598 225  HOH HOH A . 
D 4 HOH 99  1599 156  HOH HOH A . 
D 4 HOH 100 1600 115  HOH HOH A . 
D 4 HOH 101 1601 182  HOH HOH A . 
D 4 HOH 102 1602 131  HOH HOH A . 
D 4 HOH 103 1603 359  HOH HOH A . 
D 4 HOH 104 1604 444  HOH HOH A . 
D 4 HOH 105 1605 65   HOH HOH A . 
D 4 HOH 106 1606 205  HOH HOH A . 
D 4 HOH 107 1607 140  HOH HOH A . 
D 4 HOH 108 1608 226  HOH HOH A . 
D 4 HOH 109 1609 34   HOH HOH A . 
D 4 HOH 110 1610 11   HOH HOH A . 
D 4 HOH 111 1611 233  HOH HOH A . 
D 4 HOH 112 1612 24   HOH HOH A . 
D 4 HOH 113 1613 106  HOH HOH A . 
D 4 HOH 114 1614 465  HOH HOH A . 
D 4 HOH 115 1615 187  HOH HOH A . 
D 4 HOH 116 1616 144  HOH HOH A . 
D 4 HOH 117 1617 615  HOH HOH A . 
D 4 HOH 118 1618 84   HOH HOH A . 
D 4 HOH 119 1619 12   HOH HOH A . 
D 4 HOH 120 1620 99   HOH HOH A . 
D 4 HOH 121 1621 36   HOH HOH A . 
D 4 HOH 122 1622 335  HOH HOH A . 
D 4 HOH 123 1623 211  HOH HOH A . 
D 4 HOH 124 1624 429  HOH HOH A . 
D 4 HOH 125 1625 152  HOH HOH A . 
D 4 HOH 126 1626 32   HOH HOH A . 
D 4 HOH 127 1627 143  HOH HOH A . 
D 4 HOH 128 1628 87   HOH HOH A . 
D 4 HOH 129 1629 50   HOH HOH A . 
D 4 HOH 130 1630 563  HOH HOH A . 
D 4 HOH 131 1631 13   HOH HOH A . 
D 4 HOH 132 1632 332  HOH HOH A . 
D 4 HOH 133 1633 101  HOH HOH A . 
D 4 HOH 134 1634 153  HOH HOH A . 
D 4 HOH 135 1635 44   HOH HOH A . 
D 4 HOH 136 1636 227  HOH HOH A . 
D 4 HOH 137 1637 174  HOH HOH A . 
D 4 HOH 138 1638 146  HOH HOH A . 
D 4 HOH 139 1639 471  HOH HOH A . 
D 4 HOH 140 1640 45   HOH HOH A . 
D 4 HOH 141 1641 405  HOH HOH A . 
D 4 HOH 142 1642 273  HOH HOH A . 
D 4 HOH 143 1643 300  HOH HOH A . 
D 4 HOH 144 1644 16   HOH HOH A . 
D 4 HOH 145 1645 46   HOH HOH A . 
D 4 HOH 146 1646 584  HOH HOH A . 
D 4 HOH 147 1647 542  HOH HOH A . 
D 4 HOH 148 1648 112  HOH HOH A . 
D 4 HOH 149 1649 2    HOH HOH A . 
D 4 HOH 150 1650 497  HOH HOH A . 
D 4 HOH 151 1651 7    HOH HOH A . 
D 4 HOH 152 1652 206  HOH HOH A . 
D 4 HOH 153 1653 90   HOH HOH A . 
D 4 HOH 154 1654 103  HOH HOH A . 
D 4 HOH 155 1655 320  HOH HOH A . 
D 4 HOH 156 1656 165  HOH HOH A . 
D 4 HOH 157 1657 55   HOH HOH A . 
D 4 HOH 158 1658 167  HOH HOH A . 
D 4 HOH 159 1659 98   HOH HOH A . 
D 4 HOH 160 1660 614  HOH HOH A . 
D 4 HOH 161 1661 404  HOH HOH A . 
D 4 HOH 162 1662 412  HOH HOH A . 
D 4 HOH 163 1663 331  HOH HOH A . 
D 4 HOH 164 1664 86   HOH HOH A . 
D 4 HOH 165 1665 385  HOH HOH A . 
D 4 HOH 166 1666 250  HOH HOH A . 
D 4 HOH 167 1667 66   HOH HOH A . 
D 4 HOH 168 1668 351  HOH HOH A . 
D 4 HOH 169 1669 49   HOH HOH A . 
D 4 HOH 170 1670 62   HOH HOH A . 
D 4 HOH 171 1671 439  HOH HOH A . 
D 4 HOH 172 1672 210  HOH HOH A . 
D 4 HOH 173 1673 68   HOH HOH A . 
D 4 HOH 174 1674 282  HOH HOH A . 
D 4 HOH 175 1675 345  HOH HOH A . 
D 4 HOH 176 1676 249  HOH HOH A . 
D 4 HOH 177 1677 26   HOH HOH A . 
D 4 HOH 178 1678 48   HOH HOH A . 
D 4 HOH 179 1679 29   HOH HOH A . 
D 4 HOH 180 1680 42   HOH HOH A . 
D 4 HOH 181 1681 5    HOH HOH A . 
D 4 HOH 182 1682 113  HOH HOH A . 
D 4 HOH 183 1683 442  HOH HOH A . 
D 4 HOH 184 1684 8    HOH HOH A . 
D 4 HOH 185 1685 421  HOH HOH A . 
D 4 HOH 186 1686 43   HOH HOH A . 
D 4 HOH 187 1687 28   HOH HOH A . 
D 4 HOH 188 1688 564  HOH HOH A . 
D 4 HOH 189 1689 4    HOH HOH A . 
D 4 HOH 190 1690 235  HOH HOH A . 
D 4 HOH 191 1691 154  HOH HOH A . 
D 4 HOH 192 1692 104  HOH HOH A . 
D 4 HOH 193 1693 76   HOH HOH A . 
D 4 HOH 194 1694 230  HOH HOH A . 
D 4 HOH 195 1695 489  HOH HOH A . 
D 4 HOH 196 1696 287  HOH HOH A . 
D 4 HOH 197 1697 97   HOH HOH A . 
D 4 HOH 198 1698 387  HOH HOH A . 
D 4 HOH 199 1699 231  HOH HOH A . 
D 4 HOH 200 1700 107  HOH HOH A . 
D 4 HOH 201 1701 196  HOH HOH A . 
D 4 HOH 202 1702 47   HOH HOH A . 
D 4 HOH 203 1703 312  HOH HOH A . 
D 4 HOH 204 1704 14   HOH HOH A . 
D 4 HOH 205 1705 25   HOH HOH A . 
D 4 HOH 206 1706 392  HOH HOH A . 
D 4 HOH 207 1707 145  HOH HOH A . 
D 4 HOH 208 1708 17   HOH HOH A . 
D 4 HOH 209 1709 396  HOH HOH A . 
D 4 HOH 210 1710 38   HOH HOH A . 
D 4 HOH 211 1711 191  HOH HOH A . 
D 4 HOH 212 1712 130  HOH HOH A . 
D 4 HOH 213 1713 520  HOH HOH A . 
D 4 HOH 214 1714 39   HOH HOH A . 
D 4 HOH 215 1715 138  HOH HOH A . 
D 4 HOH 216 1716 137  HOH HOH A . 
D 4 HOH 217 1717 268  HOH HOH A . 
D 4 HOH 218 1718 51   HOH HOH A . 
D 4 HOH 219 1719 177  HOH HOH A . 
D 4 HOH 220 1720 555  HOH HOH A . 
D 4 HOH 221 1721 6    HOH HOH A . 
D 4 HOH 222 1722 237  HOH HOH A . 
D 4 HOH 223 1723 10   HOH HOH A . 
D 4 HOH 224 1724 533  HOH HOH A . 
D 4 HOH 225 1725 400  HOH HOH A . 
D 4 HOH 226 1726 366  HOH HOH A . 
D 4 HOH 227 1727 83   HOH HOH A . 
D 4 HOH 228 1728 85   HOH HOH A . 
D 4 HOH 229 1729 365  HOH HOH A . 
D 4 HOH 230 1730 585  HOH HOH A . 
D 4 HOH 231 1731 9    HOH HOH A . 
D 4 HOH 232 1732 243  HOH HOH A . 
D 4 HOH 233 1733 126  HOH HOH A . 
D 4 HOH 234 1734 452  HOH HOH A . 
D 4 HOH 235 1735 161  HOH HOH A . 
D 4 HOH 236 1736 222  HOH HOH A . 
D 4 HOH 237 1737 193  HOH HOH A . 
D 4 HOH 238 1738 548  HOH HOH A . 
D 4 HOH 239 1739 122  HOH HOH A . 
D 4 HOH 240 1740 134  HOH HOH A . 
D 4 HOH 241 1741 417  HOH HOH A . 
D 4 HOH 242 1742 353  HOH HOH A . 
D 4 HOH 243 1743 164  HOH HOH A . 
D 4 HOH 244 1744 383  HOH HOH A . 
D 4 HOH 245 1745 40   HOH HOH A . 
D 4 HOH 246 1746 590  HOH HOH A . 
D 4 HOH 247 1747 59   HOH HOH A . 
D 4 HOH 248 1748 587  HOH HOH A . 
D 4 HOH 249 1749 462  HOH HOH A . 
D 4 HOH 250 1750 501  HOH HOH A . 
D 4 HOH 251 1751 276  HOH HOH A . 
D 4 HOH 252 1752 269  HOH HOH A . 
D 4 HOH 253 1753 173  HOH HOH A . 
D 4 HOH 254 1754 133  HOH HOH A . 
D 4 HOH 255 1755 418  HOH HOH A . 
D 4 HOH 256 1756 57   HOH HOH A . 
D 4 HOH 257 1757 75   HOH HOH A . 
D 4 HOH 258 1758 277  HOH HOH A . 
D 4 HOH 259 1759 532  HOH HOH A . 
D 4 HOH 260 1760 432  HOH HOH A . 
D 4 HOH 261 1761 376  HOH HOH A . 
D 4 HOH 262 1762 463  HOH HOH A . 
D 4 HOH 263 1763 540  HOH HOH A . 
D 4 HOH 264 1764 91   HOH HOH A . 
D 4 HOH 265 1765 616  HOH HOH A . 
D 4 HOH 266 1766 424  HOH HOH A . 
D 4 HOH 267 1767 195  HOH HOH A . 
D 4 HOH 268 1768 125  HOH HOH A . 
D 4 HOH 269 1769 172  HOH HOH A . 
D 4 HOH 270 1770 279  HOH HOH A . 
D 4 HOH 271 1771 296  HOH HOH A . 
D 4 HOH 272 1772 200  HOH HOH A . 
D 4 HOH 273 1773 265  HOH HOH A . 
D 4 HOH 274 1774 149  HOH HOH A . 
D 4 HOH 275 1775 128  HOH HOH A . 
D 4 HOH 276 1776 105  HOH HOH A . 
D 4 HOH 277 1777 53   HOH HOH A . 
D 4 HOH 278 1778 186  HOH HOH A . 
D 4 HOH 279 1779 340  HOH HOH A . 
D 4 HOH 280 1780 189  HOH HOH A . 
D 4 HOH 281 1781 175  HOH HOH A . 
D 4 HOH 282 1782 207  HOH HOH A . 
D 4 HOH 283 1783 617  HOH HOH A . 
D 4 HOH 284 1784 272  HOH HOH A . 
D 4 HOH 285 1785 202  HOH HOH A . 
D 4 HOH 286 1786 593  HOH HOH A . 
D 4 HOH 287 1787 309  HOH HOH A . 
D 4 HOH 288 1788 611  HOH HOH A . 
D 4 HOH 289 1789 327  HOH HOH A . 
D 4 HOH 290 1790 589  HOH HOH A . 
D 4 HOH 291 1791 571  HOH HOH A . 
D 4 HOH 292 1792 162  HOH HOH A . 
D 4 HOH 293 1793 198  HOH HOH A . 
D 4 HOH 294 1794 136  HOH HOH A . 
D 4 HOH 295 1795 620  HOH HOH A . 
D 4 HOH 296 1796 92   HOH HOH A . 
D 4 HOH 297 1797 552  HOH HOH A . 
D 4 HOH 298 1798 389  HOH HOH A . 
D 4 HOH 299 1799 596  HOH HOH A . 
D 4 HOH 300 1800 531  HOH HOH A . 
D 4 HOH 301 1801 56   HOH HOH A . 
D 4 HOH 302 1802 121  HOH HOH A . 
D 4 HOH 303 1803 254  HOH HOH A . 
D 4 HOH 304 1804 132  HOH HOH A . 
D 4 HOH 305 1805 291  HOH HOH A . 
D 4 HOH 306 1806 579  HOH HOH A . 
D 4 HOH 307 1807 318  HOH HOH A . 
D 4 HOH 308 1808 188  HOH HOH A . 
D 4 HOH 309 1809 234  HOH HOH A . 
D 4 HOH 310 1810 244  HOH HOH A . 
D 4 HOH 311 1811 185  HOH HOH A . 
D 4 HOH 312 1812 346  HOH HOH A . 
D 4 HOH 313 1813 77   HOH HOH A . 
D 4 HOH 314 1814 570  HOH HOH A . 
D 4 HOH 315 1815 73   HOH HOH A . 
D 4 HOH 316 1816 409  HOH HOH A . 
D 4 HOH 317 1817 449  HOH HOH A . 
D 4 HOH 318 1818 78   HOH HOH A . 
D 4 HOH 319 1819 79   HOH HOH A . 
D 4 HOH 320 1820 342  HOH HOH A . 
D 4 HOH 321 1821 120  HOH HOH A . 
D 4 HOH 322 1822 290  HOH HOH A . 
D 4 HOH 323 1823 480  HOH HOH A . 
D 4 HOH 324 1824 311  HOH HOH A . 
D 4 HOH 325 1825 355  HOH HOH A . 
D 4 HOH 326 1826 437  HOH HOH A . 
D 4 HOH 327 1827 603  HOH HOH A . 
D 4 HOH 328 1828 388  HOH HOH A . 
D 4 HOH 329 1829 605  HOH HOH A . 
D 4 HOH 330 1830 333  HOH HOH A . 
D 4 HOH 331 1831 375  HOH HOH A . 
D 4 HOH 332 1832 114  HOH HOH A . 
D 4 HOH 333 1833 394  HOH HOH A . 
D 4 HOH 334 1834 440  HOH HOH A . 
D 4 HOH 335 1835 363  HOH HOH A . 
D 4 HOH 336 1836 466  HOH HOH A . 
D 4 HOH 337 1837 308  HOH HOH A . 
D 4 HOH 338 1838 502  HOH HOH A . 
D 4 HOH 339 1839 403  HOH HOH A . 
D 4 HOH 340 1840 360  HOH HOH A . 
D 4 HOH 341 1841 374  HOH HOH A . 
D 4 HOH 342 1842 329  HOH HOH A . 
D 4 HOH 343 1843 602  HOH HOH A . 
D 4 HOH 344 1844 411  HOH HOH A . 
D 4 HOH 345 1845 361  HOH HOH A . 
D 4 HOH 346 1846 490  HOH HOH A . 
D 4 HOH 347 1847 464  HOH HOH A . 
D 4 HOH 348 1848 307  HOH HOH A . 
D 4 HOH 349 1849 556  HOH HOH A . 
D 4 HOH 350 1850 155  HOH HOH A . 
D 4 HOH 351 1851 178  HOH HOH A . 
D 4 HOH 352 1852 551  HOH HOH A . 
D 4 HOH 353 1853 228  HOH HOH A . 
D 4 HOH 354 1854 285  HOH HOH A . 
D 4 HOH 355 1855 457  HOH HOH A . 
D 4 HOH 356 1856 264  HOH HOH A . 
D 4 HOH 357 1857 229  HOH HOH A . 
D 4 HOH 358 1858 582  HOH HOH A . 
D 4 HOH 359 1859 292  HOH HOH A . 
D 4 HOH 360 1860 323  HOH HOH A . 
D 4 HOH 361 1861 93   HOH HOH A . 
D 4 HOH 362 1862 129  HOH HOH A . 
D 4 HOH 363 1863 301  HOH HOH A . 
D 4 HOH 364 1864 102  HOH HOH A . 
D 4 HOH 365 1865 219  HOH HOH A . 
D 4 HOH 366 1866 486  HOH HOH A . 
D 4 HOH 367 1867 433  HOH HOH A . 
D 4 HOH 368 1868 216  HOH HOH A . 
D 4 HOH 369 1869 613  HOH HOH A . 
D 4 HOH 370 1870 492  HOH HOH A . 
D 4 HOH 371 1871 118  HOH HOH A . 
D 4 HOH 372 1872 199  HOH HOH A . 
D 4 HOH 373 1873 458  HOH HOH A . 
D 4 HOH 374 1874 515  HOH HOH A . 
D 4 HOH 375 1875 369  HOH HOH A . 
D 4 HOH 376 1876 299  HOH HOH A . 
D 4 HOH 377 1877 448  HOH HOH A . 
D 4 HOH 378 1878 377  HOH HOH A . 
D 4 HOH 379 1879 37   HOH HOH A . 
D 4 HOH 380 1880 349  HOH HOH A . 
D 4 HOH 381 1881 595  HOH HOH A . 
D 4 HOH 382 1882 373  HOH HOH A . 
D 4 HOH 383 1883 479  HOH HOH A . 
D 4 HOH 384 1884 117  HOH HOH A . 
D 4 HOH 385 1885 321  HOH HOH A . 
D 4 HOH 386 1886 443  HOH HOH A . 
D 4 HOH 387 1887 562  HOH HOH A . 
D 4 HOH 388 1888 606  HOH HOH A . 
D 4 HOH 389 1889 260  HOH HOH A . 
D 4 HOH 390 1890 239  HOH HOH A . 
D 4 HOH 391 1891 159  HOH HOH A . 
D 4 HOH 392 1892 337  HOH HOH A . 
D 4 HOH 393 1893 357  HOH HOH A . 
D 4 HOH 394 1894 594  HOH HOH A . 
D 4 HOH 395 1895 274  HOH HOH A . 
D 4 HOH 396 1896 302  HOH HOH A . 
D 4 HOH 397 1897 304  HOH HOH A . 
D 4 HOH 398 1898 402  HOH HOH A . 
D 4 HOH 399 1899 459  HOH HOH A . 
D 4 HOH 400 1900 213  HOH HOH A . 
D 4 HOH 401 1901 259  HOH HOH A . 
D 4 HOH 402 1902 476  HOH HOH A . 
D 4 HOH 403 1903 170  HOH HOH A . 
D 4 HOH 404 1904 74   HOH HOH A . 
D 4 HOH 405 1905 567  HOH HOH A . 
D 4 HOH 406 1906 241  HOH HOH A . 
D 4 HOH 407 1907 512  HOH HOH A . 
D 4 HOH 408 1908 240  HOH HOH A . 
D 4 HOH 409 1909 127  HOH HOH A . 
D 4 HOH 410 1910 180  HOH HOH A . 
D 4 HOH 411 1911 528  HOH HOH A . 
D 4 HOH 412 1912 245  HOH HOH A . 
D 4 HOH 413 1913 278  HOH HOH A . 
D 4 HOH 414 1914 258  HOH HOH A . 
D 4 HOH 415 1915 367  HOH HOH A . 
D 4 HOH 416 1916 271  HOH HOH A . 
D 4 HOH 417 1917 336  HOH HOH A . 
D 4 HOH 418 1918 386  HOH HOH A . 
D 4 HOH 419 1919 288  HOH HOH A . 
D 4 HOH 420 1920 194  HOH HOH A . 
D 4 HOH 421 1921 319  HOH HOH A . 
D 4 HOH 422 1922 217  HOH HOH A . 
D 4 HOH 423 1923 151  HOH HOH A . 
D 4 HOH 424 1924 184  HOH HOH A . 
D 4 HOH 425 1925 238  HOH HOH A . 
D 4 HOH 426 1926 356  HOH HOH A . 
D 4 HOH 427 1927 478  HOH HOH A . 
D 4 HOH 428 1928 212  HOH HOH A . 
D 4 HOH 429 1929 362  HOH HOH A . 
D 4 HOH 430 1930 467  HOH HOH A . 
D 4 HOH 431 1931 420  HOH HOH A . 
D 4 HOH 432 1932 434  HOH HOH A . 
D 4 HOH 433 1933 391  HOH HOH A . 
D 4 HOH 434 1934 586  HOH HOH A . 
D 4 HOH 435 1935 247  HOH HOH A . 
D 4 HOH 436 1936 372  HOH HOH A . 
D 4 HOH 437 1937 163  HOH HOH A . 
D 4 HOH 438 1938 438  HOH HOH A . 
D 4 HOH 439 1939 208  HOH HOH A . 
D 4 HOH 440 1940 220  HOH HOH A . 
D 4 HOH 441 1941 381  HOH HOH A . 
D 4 HOH 442 1942 559  HOH HOH A . 
D 4 HOH 443 1943 461  HOH HOH A . 
D 4 HOH 444 1944 455  HOH HOH A . 
D 4 HOH 445 1945 618  HOH HOH A . 
D 4 HOH 446 1946 470  HOH HOH A . 
D 4 HOH 447 1947 454  HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.dependencies 
_software.description 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.pdbx_ordinal 
_software.type 
_software.version 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? STARGazer ? ? 1 ? .        
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? STARGazer ? ? 2 ? .        
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER    ? ? 3 ? .        
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC    ? ? 4 ? 5.8.0425 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9KKC 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     59.29 
_cell.length_a_esd                 ? 
_cell.length_b                     59.29 
_cell.length_b_esd                 ? 
_cell.length_c                     187.24 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9KKC 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                154 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 32 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9KKC 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'NEUTRON DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             ? 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          ? 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'BATCH MODE' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    PEG2000 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     DIFFRACTOMETER 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         iBIX 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-03-02 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   L 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             LAUE 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             neutron 
# 
loop_
_diffrn_radiation_wavelength.id 
_diffrn_radiation_wavelength.wavelength 
_diffrn_radiation_wavelength.wt 
1 2.05 1.0 
2 5.38 1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      'SPALLATION SOURCE' 
_diffrn_source.target                      ? 
_diffrn_source.type                        'J-PARC MLF BEAMLINE BL-03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        2.05-5.38 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL-03 
_diffrn_source.pdbx_synchrotron_site       'JPARC MLF' 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9KKC 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.80 
_reflns.d_resolution_low                               19.415 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     36250 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.5 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                9.0226 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          6.34 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                0.1548 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.9682 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.80 
_reflns_shell.d_res_low                                     1.86 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             3539 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.7180 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.3492 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            0.043 
_refine.aniso_B[1][2]                            0.022 
_refine.aniso_B[1][3]                            -0.000 
_refine.aniso_B[2][2]                            0.043 
_refine.aniso_B[2][3]                            -0.000 
_refine.aniso_B[3][3]                            -0.141 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               24.332 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.950 
_refine.correlation_coeff_Fo_to_Fc_free          0.894 
_refine.details                                  'Hydrogens have been used if present in the input file' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9KKC 
_refine.pdbx_refine_id                           'NEUTRON DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.800 
_refine.ls_d_res_low                             19.415 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     36248 
_refine.ls_number_reflns_R_free                  1764 
_refine.ls_number_reflns_R_work                  34484 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.577 
_refine.ls_percent_reflns_R_free                 4.866 
_refine.ls_R_factor_all                          0.193 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2449 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1904 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      5H59 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.186 
_refine.pdbx_overall_ESU_R_Free                  0.164 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             5.225 
_refine.overall_SU_ML                            0.153 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'NEUTRON DIFFRACTION' ? 0.008  0.014     4205  ? r_bond_refined_d               ? ? 
'NEUTRON DIFFRACTION' ? 0.001  0.017     1975  ? r_bond_other_d                 ? ? 
'NEUTRON DIFFRACTION' ? 0.000  0.005     7752  ? r_ext_dist_refined_b           ? ? 
'NEUTRON DIFFRACTION' ? 1.678  2.014     5201  ? r_angle_refined_deg            ? ? 
'NEUTRON DIFFRACTION' ? 0.564  1.708     4810  ? r_angle_other_deg              ? ? 
'NEUTRON DIFFRACTION' ? 6.443  5.000     327   ? r_dihedral_angle_1_deg         ? ? 
'NEUTRON DIFFRACTION' ? 8.061  10643.245 94    ? r_dihedral_angle_2_deg         ? ? 
'NEUTRON DIFFRACTION' ? 14.958 10.000    522   ? r_dihedral_angle_3_deg         ? ? 
'NEUTRON DIFFRACTION' ? 3.895  10.000    153   ? r_dihedral_angle_other_3_deg   ? ? 
'NEUTRON DIFFRACTION' ? 16.481 10.000    122   ? r_dihedral_angle_6_deg         ? ? 
'NEUTRON DIFFRACTION' ? 14.511 10.000    31    ? r_dihedral_angle_other_6_deg   ? ? 
'NEUTRON DIFFRACTION' ? 0.088  0.200     375   ? r_chiral_restr                 ? ? 
'NEUTRON DIFFRACTION' ? 0.011  0.020     3686  ? r_gen_planes_refined           ? ? 
'NEUTRON DIFFRACTION' ? 0.000  0.020     163   ? r_gen_planes_other             ? ? 
'NEUTRON DIFFRACTION' ? 0.218  0.200     1267  ? r_nbd_refined                  ? ? 
'NEUTRON DIFFRACTION' ? 0.163  0.200     1232  ? r_symmetry_nbd_other           ? ? 
'NEUTRON DIFFRACTION' ? 0.183  0.200     1217  ? r_nbtor_refined                ? ? 
'NEUTRON DIFFRACTION' ? 0.053  0.200     99    ? r_symmetry_nbtor_other         ? ? 
'NEUTRON DIFFRACTION' ? 0.198  0.200     379   ? r_xyhbond_nbd_refined          ? ? 
'NEUTRON DIFFRACTION' ? 0.228  0.200     71    ? r_symmetry_nbd_refined         ? ? 
'NEUTRON DIFFRACTION' ? 0.194  0.200     66    ? r_nbd_other                    ? ? 
'NEUTRON DIFFRACTION' ? 0.176  0.200     43    ? r_symmetry_xyhbond_nbd_refined ? ? 
'NEUTRON DIFFRACTION' ? 1.727  1.954     1610  ? r_mcbond_it                    ? ? 
'NEUTRON DIFFRACTION' ? 1.727  1.954     1610  ? r_mcbond_other                 ? ? 
'NEUTRON DIFFRACTION' ? 2.392  3.396     2240  ? r_mcangle_it                   ? ? 
'NEUTRON DIFFRACTION' ? 2.392  3.396     2241  ? r_mcangle_other                ? ? 
'NEUTRON DIFFRACTION' ? 2.428  2.731     2595  ? r_scbond_it                    ? ? 
'NEUTRON DIFFRACTION' ? 2.529  2.369     1699  ? r_scbond_other                 ? ? 
'NEUTRON DIFFRACTION' ? 3.696  4.247     2961  ? r_scangle_it                   ? ? 
'NEUTRON DIFFRACTION' ? 3.895  4.107     2515  ? r_scangle_other                ? ? 
'NEUTRON DIFFRACTION' ? 5.377  31.345    10076 ? r_lrange_it                    ? ? 
'NEUTRON DIFFRACTION' ? 5.052  29.617    9686  ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'NEUTRON DIFFRACTION' 1.800 1.846  2610 . 113 2483 99.4636  . 0.316 . . 0.317 . . . . . 0.310 . 20 . 0.922 0.930 0.309 
'NEUTRON DIFFRACTION' 1.846 1.896  2564 . 146 2413 99.8050  . 0.292 . . 0.292 . . . . . 0.282 . 20 . 0.931 0.930 0.295 
'NEUTRON DIFFRACTION' 1.896 1.951  2442 . 121 2317 99.8362  . 0.275 . . 0.275 . . . . . 0.262 . 20 . 0.943 0.939 0.284 
'NEUTRON DIFFRACTION' 1.951 2.010  2419 . 134 2284 99.9587  . 0.260 . . 0.258 . . . . . 0.242 . 20 . 0.949 0.934 0.294 
'NEUTRON DIFFRACTION' 2.010 2.075  2375 . 131 2242 99.9158  . 0.234 . . 0.231 . . . . . 0.210 . 20 . 0.960 0.944 0.276 
'NEUTRON DIFFRACTION' 2.075 2.147  2285 . 132 2152 99.9562  . 0.217 . . 0.216 . . . . . 0.191 . 20 . 0.966 0.965 0.228 
'NEUTRON DIFFRACTION' 2.147 2.227  2199 . 94  2105 100.0000 . 0.207 . . 0.205 . . . . . 0.176 . 20 . 0.970 0.952 0.243 
'NEUTRON DIFFRACTION' 2.227 2.317  2104 . 115 1989 100.0000 . 0.193 . . 0.190 . . . . . 0.161 . 20 . 0.974 0.956 0.236 
'NEUTRON DIFFRACTION' 2.317 2.419  2066 . 108 1958 100.0000 . 0.195 . . 0.191 . . . . . 0.157 . 20 . 0.976 0.955 0.253 
'NEUTRON DIFFRACTION' 2.419 2.535  1950 . 94  1856 100.0000 . 0.176 . . 0.173 . . . . . 0.140 . 20 . 0.980 0.963 0.241 
'NEUTRON DIFFRACTION' 2.535 2.669  1892 . 92  1800 100.0000 . 0.178 . . 0.174 . . . . . 0.141 . 20 . 0.981 0.967 0.248 
'NEUTRON DIFFRACTION' 2.669 2.828  1771 . 75  1695 99.9435  . 0.171 . . 0.169 . . . . . 0.136 . 20 . 0.982 0.970 0.205 
'NEUTRON DIFFRACTION' 2.828 3.019  1685 . 69  1616 100.0000 . 0.163 . . 0.160 . . . . . 0.124 . 20 . 0.983 0.966 0.236 
'NEUTRON DIFFRACTION' 3.019 3.254  1559 . 85  1474 100.0000 . 0.156 . . 0.153 . . . . . 0.127 . 20 . 0.985 0.971 0.209 
'NEUTRON DIFFRACTION' 3.254 3.554  1460 . 57  1402 99.9315  . 0.175 . . 0.172 . . . . . 0.149 . 20 . 0.984 0.969 0.240 
'NEUTRON DIFFRACTION' 3.554 3.957  1354 . 57  1292 99.6307  . 0.157 . . 0.156 . . . . . 0.135 . 20 . 0.987 0.977 0.193 
'NEUTRON DIFFRACTION' 3.957 4.538  1180 . 51  1126 99.7458  . 0.141 . . 0.138 . . . . . 0.115 . 20 . 0.990 0.977 0.217 
'NEUTRON DIFFRACTION' 4.538 5.484  1043 . 41  1002 100.0000 . 0.131 . . 0.128 . . . . . 0.106 . 20 . 0.991 0.975 0.233 
'NEUTRON DIFFRACTION' 5.484 7.463  841  . 35  804  99.7622  . 0.149 . . 0.145 . . . . . 0.117 . 20 . 0.988 0.975 0.242 
'NEUTRON DIFFRACTION' 7.463 19.415 562  . 14  474  86.8327  . 0.178 . . 0.175 . . . . . 0.147 . 20 . 0.981 0.943 0.288 
# 
_struct.entry_id                     9KKC 
_struct.title                        'Neutron structure of Ferredoxin-NADP+ reductase from maize root -Oxidized form' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9KKC 
_struct_keywords.text            'electron transfer, Flavoprotein, OXIDOREDUCTASE' 
_struct_keywords.pdbx_keywords   OXIDOREDUCTASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    B4G043_MAIZE 
_struct_ref.pdbx_db_accession          B4G043 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;SKVSVAPLHLESAKEPPLNTYKPKEPFTATIVSVESLVGPKAPGETCHIVIDHGGNVPYWEGQSYGVIPPGENPKKPGAP
QNVRLYSIASTRYGDNFDGRTGSLCVRRAVYYDPETGKEDPSKNGVCSNFLCNSKPGDKIQLTGPSGKIMLLPEEDPNAT
HIMIATGTGVAPFRGYLRRMFMEDVPNYRFGGLAWLFLGVANSDSLLYDEEFTSYLKQYPDNFRYDKALSREQKNRSGGK
MYVQDKIEEYSDEIFKLLDGGAHIYFCGLKGMMPGIQDTLKKVAERRGESWDQKLAQLKKNKQWHVEVY
;
_struct_ref.pdbx_align_begin           73 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9KKC 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 309 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             B4G043 
_struct_ref_seq.db_align_beg                  73 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  381 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1009 
_struct_ref_seq.pdbx_auth_seq_align_end       1317 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO A 7   ? SER A 12  ? PRO A 1015 SER A 1020 5 ? 6  
HELX_P HELX_P2  AA2 ASP A 120 ? ASN A 124 ? ASP A 1128 ASN A 1132 5 ? 5  
HELX_P HELX_P3  AA3 GLY A 125 ? ASN A 133 ? GLY A 1133 ASN A 1141 1 ? 9  
HELX_P HELX_P4  AA4 VAL A 170 ? MET A 182 ? VAL A 1178 MET A 1190 1 ? 13 
HELX_P HELX_P5  AA5 ASN A 202 ? LEU A 206 ? ASN A 1210 LEU A 1214 5 ? 5  
HELX_P HELX_P6  AA6 TYR A 208 ? TYR A 219 ? TYR A 1216 TYR A 1227 1 ? 12 
HELX_P HELX_P7  AA7 TYR A 242 ? TYR A 250 ? TYR A 1250 TYR A 1258 1 ? 9  
HELX_P HELX_P8  AA8 TYR A 250 ? GLY A 260 ? TYR A 1258 GLY A 1268 1 ? 11 
HELX_P HELX_P9  AA9 MET A 272 ? ARG A 287 ? MET A 1280 ARG A 1295 1 ? 16 
HELX_P HELX_P10 AB1 SER A 290 ? ASN A 301 ? SER A 1298 ASN A 1309 1 ? 12 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 47 SG A ? ? 1_555 A CYS 132 SG ? ? A CYS 1055 A CYS 1140 1_555 ? ? ? ? ? ? ? 2.041 ? ? 
disulf2 disulf ? ? A CYS 47 SG B ? ? 1_555 A CYS 132 SG ? ? A CYS 1055 A CYS 1140 1_555 ? ? ? ? ? ? ? 2.716 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 47 A CYS A 132 ? CYS A 1055 ? 1_555 CYS A 1140 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS A 47 B CYS A 132 ? CYS A 1055 ? 1_555 CYS A 1140 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ALA 6   A . ? ALA 1014 A PRO 7   A ? PRO 1015 A 1 -3.48 
2 GLY 144 A . ? GLY 1152 A PRO 145 A ? PRO 1153 A 1 -0.75 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 2 ? 
AA3 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? parallel      
AA3 3 4 ? parallel      
AA3 4 5 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ARG A 84  ? SER A 87  ? ARG A 1092 SER A 1095 
AA1 2 SER A 64  ? ILE A 68  ? SER A 1072 ILE A 1076 
AA1 3 LYS A 139 ? SER A 146 ? LYS A 1147 SER A 1154 
AA1 4 PHE A 27  ? SER A 36  ? PHE A 1035 SER A 1044 
AA1 5 THR A 46  ? ASP A 52  ? THR A 1054 ASP A 1060 
AA1 6 THR A 101 ? ARG A 107 ? THR A 1109 ARG A 1115 
AA2 1 GLU A 72  ? ASN A 73  ? GLU A 1080 ASN A 1081 
AA2 2 LYS A 76  ? PRO A 80  ? LYS A 1084 PRO A 1088 
AA3 1 PHE A 223 ? LEU A 229 ? PHE A 1231 LEU A 1237 
AA3 2 LEU A 193 ? VAL A 200 ? LEU A 1201 VAL A 1208 
AA3 3 THR A 160 ? THR A 166 ? THR A 1168 THR A 1174 
AA3 4 HIS A 263 ? LEU A 269 ? HIS A 1271 LEU A 1277 
AA3 5 TRP A 304 ? TYR A 309 ? TRP A 1312 TYR A 1317 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O TYR A 86  ? O TYR A 1094 N TYR A 65  ? N TYR A 1073 
AA1 2 3 N GLY A 66  ? N GLY A 1074 O THR A 143 ? O THR A 1151 
AA1 3 4 O LEU A 142 ? O LEU A 1150 N PHE A 27  ? N PHE A 1035 
AA1 4 5 N THR A 30  ? N THR A 1038 O ASP A 52  ? O ASP A 1060 
AA1 5 6 N ILE A 51  ? N ILE A 1059 O GLY A 102 ? O GLY A 1110 
AA2 1 2 N ASN A 73  ? N ASN A 1081 O ALA A 79  ? O ALA A 1087 
AA3 1 2 O ARG A 224 ? O ARG A 1232 N LEU A 196 ? N LEU A 1204 
AA3 2 3 O PHE A 197 ? O PHE A 1205 N MET A 163 ? N MET A 1171 
AA3 3 4 N ILE A 162 ? N ILE A 1170 O HIS A 263 ? O HIS A 1271 
AA3 4 5 N PHE A 266 ? N PHE A 1274 O GLU A 307 ? O GLU A 1315 
# 
_pdbx_entry_details.entry_id                   9KKC 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 OD1 A ASP 1128 ? ? HG A SER 1130 ? ? 1.44 
2  1 OE1 A GLN 1252 ? A H2 A HOH 1511 ? ? 1.48 
3  1 OD1 A ASP 1234 ? ? H1 A HOH 1519 ? ? 1.49 
4  1 OD1 A ASN 1243 ? B H2 A HOH 1508 ? ? 1.49 
5  1 O   A GLU 1080 ? ? H1 A HOH 1522 ? ? 1.50 
6  1 O   A SER 1012 ? ? H1 A HOH 1506 ? ? 1.51 
7  1 O   A HOH 1542 ? ? H2 A HOH 1843 ? ? 1.51 
8  1 O   A HOH 1701 ? ? H1 A HOH 1868 ? ? 1.53 
9  1 H1  A HOH 1647 ? ? O  A HOH 1661 ? ? 1.54 
10 1 H2  A HOH 1664 ? ? O  A HOH 1756 ? ? 1.55 
11 1 HZ1 A LYS 1147 ? ? O  A HOH 1538 ? ? 1.57 
12 1 H1  A HOH 1799 ? ? O  A HOH 1888 ? ? 1.57 
13 1 OD1 A ASN 1230 ? ? H1 A HOH 1516 ? ? 1.58 
14 1 OD1 A ASP 1286 ? ? H2 A HOH 1529 ? ? 1.58 
15 1 O   A HOH 1584 ? ? H2 A HOH 1642 ? ? 1.59 
16 1 H1  A HOH 1703 ? ? O  A HOH 1916 ? ? 1.59 
17 1 OG  A SER 1222 ? ? H2 A HOH 1502 ? ? 1.59 
18 1 O   A ASP 1103 ? ? H2 A HOH 1547 ? ? 1.59 
19 1 O   A ARG 1115 ? ? H2 A HOH 1546 ? ? 1.59 
20 1 H1  A HOH 1794 ? ? O  A HOH 1860 ? ? 1.59 
21 1 O   A HOH 1530 ? ? H2 A HOH 1693 ? ? 1.60 
22 1 O2A A FAD 1401 ? ? O  A HOH 1501 ? ? 2.04 
23 1 O   A HOH 1551 ? ? O  A HOH 1590 ? ? 2.10 
24 1 OG  A SER 1222 ? ? O  A HOH 1502 ? ? 2.18 
# 
_pdbx_validate_symm_contact.id                1 
_pdbx_validate_symm_contact.PDB_model_num     1 
_pdbx_validate_symm_contact.auth_atom_id_1    OD2 
_pdbx_validate_symm_contact.auth_asym_id_1    A 
_pdbx_validate_symm_contact.auth_comp_id_1    ASP 
_pdbx_validate_symm_contact.auth_seq_id_1     1128 
_pdbx_validate_symm_contact.PDB_ins_code_1    ? 
_pdbx_validate_symm_contact.label_alt_id_1    ? 
_pdbx_validate_symm_contact.site_symmetry_1   1_555 
_pdbx_validate_symm_contact.auth_atom_id_2    HZ2 
_pdbx_validate_symm_contact.auth_asym_id_2    A 
_pdbx_validate_symm_contact.auth_comp_id_2    LYS 
_pdbx_validate_symm_contact.auth_seq_id_2     1147 
_pdbx_validate_symm_contact.PDB_ins_code_2    ? 
_pdbx_validate_symm_contact.label_alt_id_2    ? 
_pdbx_validate_symm_contact.site_symmetry_2   5_445 
_pdbx_validate_symm_contact.dist              1.55 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             N 
_pdbx_validate_rmsd_angle.auth_asym_id_1             A 
_pdbx_validate_rmsd_angle.auth_comp_id_1             GLU 
_pdbx_validate_rmsd_angle.auth_seq_id_1              1293 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             CA 
_pdbx_validate_rmsd_angle.auth_asym_id_2             A 
_pdbx_validate_rmsd_angle.auth_comp_id_2             GLU 
_pdbx_validate_rmsd_angle.auth_seq_id_2              1293 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             CB 
_pdbx_validate_rmsd_angle.auth_asym_id_3             A 
_pdbx_validate_rmsd_angle.auth_comp_id_3             GLU 
_pdbx_validate_rmsd_angle.auth_seq_id_3              1293 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                123.52 
_pdbx_validate_rmsd_angle.angle_target_value         110.60 
_pdbx_validate_rmsd_angle.angle_deviation            12.92 
_pdbx_validate_rmsd_angle.angle_standard_deviation   1.80 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 LYS A 1084 ? ? -161.47 83.00   
2 1 ASP A 1128 ? ? -172.42 109.88  
3 1 ASN A 1243 ? B -61.81  -179.78 
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    A 
_pdbx_validate_planes.auth_seq_id     1244 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    A 
_pdbx_validate_planes.rmsd            0.138 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? A HOH 1944 ? 5.86 . 
2 1 O ? A HOH 1945 ? 5.98 . 
3 1 O ? A HOH 1946 ? 6.07 . 
4 1 O ? A HOH 1947 ? 6.42 . 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N N N 1   
ALA CA     C N S 2   
ALA C      C N N 3   
ALA O      O N N 4   
ALA CB     C N N 5   
ALA OXT    O N N 6   
ALA H      H N N 7   
ALA H2     H N N 8   
ALA HA     H N N 9   
ALA HB1    H N N 10  
ALA HB2    H N N 11  
ALA HB3    H N N 12  
ALA HXT    H N N 13  
ARG N      N N N 14  
ARG CA     C N S 15  
ARG C      C N N 16  
ARG O      O N N 17  
ARG CB     C N N 18  
ARG CG     C N N 19  
ARG CD     C N N 20  
ARG NE     N N N 21  
ARG CZ     C N N 22  
ARG NH1    N N N 23  
ARG NH2    N N N 24  
ARG OXT    O N N 25  
ARG H      H N N 26  
ARG H2     H N N 27  
ARG HA     H N N 28  
ARG HB2    H N N 29  
ARG HB3    H N N 30  
ARG HG2    H N N 31  
ARG HG3    H N N 32  
ARG HD2    H N N 33  
ARG HD3    H N N 34  
ARG HE     H N N 35  
ARG HH11   H N N 36  
ARG HH12   H N N 37  
ARG HH21   H N N 38  
ARG HH22   H N N 39  
ARG HXT    H N N 40  
ASN N      N N N 41  
ASN CA     C N S 42  
ASN C      C N N 43  
ASN O      O N N 44  
ASN CB     C N N 45  
ASN CG     C N N 46  
ASN OD1    O N N 47  
ASN ND2    N N N 48  
ASN OXT    O N N 49  
ASN H      H N N 50  
ASN H2     H N N 51  
ASN HA     H N N 52  
ASN HB2    H N N 53  
ASN HB3    H N N 54  
ASN HD21   H N N 55  
ASN HD22   H N N 56  
ASN HXT    H N N 57  
ASP N      N N N 58  
ASP CA     C N S 59  
ASP C      C N N 60  
ASP O      O N N 61  
ASP CB     C N N 62  
ASP CG     C N N 63  
ASP OD1    O N N 64  
ASP OD2    O N N 65  
ASP OXT    O N N 66  
ASP H      H N N 67  
ASP H2     H N N 68  
ASP HA     H N N 69  
ASP HB2    H N N 70  
ASP HB3    H N N 71  
ASP HD2    H N N 72  
ASP HXT    H N N 73  
CYS N      N N N 74  
CYS CA     C N R 75  
CYS C      C N N 76  
CYS O      O N N 77  
CYS CB     C N N 78  
CYS SG     S N N 79  
CYS OXT    O N N 80  
CYS H      H N N 81  
CYS H2     H N N 82  
CYS HA     H N N 83  
CYS HB2    H N N 84  
CYS HB3    H N N 85  
CYS HG     H N N 86  
CYS HXT    H N N 87  
FAD PA     P N R 88  
FAD O1A    O N N 89  
FAD O2A    O N N 90  
FAD O5B    O N N 91  
FAD C5B    C N N 92  
FAD C4B    C N R 93  
FAD O4B    O N N 94  
FAD C3B    C N S 95  
FAD O3B    O N N 96  
FAD C2B    C N R 97  
FAD O2B    O N N 98  
FAD C1B    C N R 99  
FAD N9A    N Y N 100 
FAD C8A    C Y N 101 
FAD N7A    N Y N 102 
FAD C5A    C Y N 103 
FAD C6A    C Y N 104 
FAD N6A    N N N 105 
FAD N1A    N Y N 106 
FAD C2A    C Y N 107 
FAD N3A    N Y N 108 
FAD C4A    C Y N 109 
FAD N1     N N N 110 
FAD C2     C N N 111 
FAD O2     O N N 112 
FAD N3     N N N 113 
FAD C4     C N N 114 
FAD O4     O N N 115 
FAD C4X    C N N 116 
FAD N5     N N N 117 
FAD C5X    C Y N 118 
FAD C6     C Y N 119 
FAD C7     C Y N 120 
FAD C7M    C N N 121 
FAD C8     C Y N 122 
FAD C8M    C N N 123 
FAD C9     C Y N 124 
FAD C9A    C Y N 125 
FAD N10    N N N 126 
FAD C10    C N N 127 
FAD "C1'"  C N N 128 
FAD "C2'"  C N S 129 
FAD "O2'"  O N N 130 
FAD "C3'"  C N S 131 
FAD "O3'"  O N N 132 
FAD "C4'"  C N R 133 
FAD "O4'"  O N N 134 
FAD "C5'"  C N N 135 
FAD "O5'"  O N N 136 
FAD P      P N R 137 
FAD O1P    O N N 138 
FAD O2P    O N N 139 
FAD O3P    O N N 140 
FAD HOA2   H N N 141 
FAD H51A   H N N 142 
FAD H52A   H N N 143 
FAD H4B    H N N 144 
FAD H3B    H N N 145 
FAD HO3A   H N N 146 
FAD H2B    H N N 147 
FAD HO2A   H N N 148 
FAD H1B    H N N 149 
FAD H8A    H N N 150 
FAD H61A   H N N 151 
FAD H62A   H N N 152 
FAD H2A    H N N 153 
FAD HN3    H N N 154 
FAD H6     H N N 155 
FAD HM71   H N N 156 
FAD HM72   H N N 157 
FAD HM73   H N N 158 
FAD HM81   H N N 159 
FAD HM82   H N N 160 
FAD HM83   H N N 161 
FAD H9     H N N 162 
FAD "H1'1" H N N 163 
FAD "H1'2" H N N 164 
FAD "H2'"  H N N 165 
FAD "HO2'" H N N 166 
FAD "H3'"  H N N 167 
FAD "HO3'" H N N 168 
FAD "H4'"  H N N 169 
FAD "HO4'" H N N 170 
FAD "H5'1" H N N 171 
FAD "H5'2" H N N 172 
FAD HOP2   H N N 173 
GLN N      N N N 174 
GLN CA     C N S 175 
GLN C      C N N 176 
GLN O      O N N 177 
GLN CB     C N N 178 
GLN CG     C N N 179 
GLN CD     C N N 180 
GLN OE1    O N N 181 
GLN NE2    N N N 182 
GLN OXT    O N N 183 
GLN H      H N N 184 
GLN H2     H N N 185 
GLN HA     H N N 186 
GLN HB2    H N N 187 
GLN HB3    H N N 188 
GLN HG2    H N N 189 
GLN HG3    H N N 190 
GLN HE21   H N N 191 
GLN HE22   H N N 192 
GLN HXT    H N N 193 
GLU N      N N N 194 
GLU CA     C N S 195 
GLU C      C N N 196 
GLU O      O N N 197 
GLU CB     C N N 198 
GLU CG     C N N 199 
GLU CD     C N N 200 
GLU OE1    O N N 201 
GLU OE2    O N N 202 
GLU OXT    O N N 203 
GLU H      H N N 204 
GLU H2     H N N 205 
GLU HA     H N N 206 
GLU HB2    H N N 207 
GLU HB3    H N N 208 
GLU HG2    H N N 209 
GLU HG3    H N N 210 
GLU HE2    H N N 211 
GLU HXT    H N N 212 
GLY N      N N N 213 
GLY CA     C N N 214 
GLY C      C N N 215 
GLY O      O N N 216 
GLY OXT    O N N 217 
GLY H      H N N 218 
GLY H2     H N N 219 
GLY HA2    H N N 220 
GLY HA3    H N N 221 
GLY HXT    H N N 222 
HIS N      N N N 223 
HIS CA     C N S 224 
HIS C      C N N 225 
HIS O      O N N 226 
HIS CB     C N N 227 
HIS CG     C Y N 228 
HIS ND1    N Y N 229 
HIS CD2    C Y N 230 
HIS CE1    C Y N 231 
HIS NE2    N Y N 232 
HIS OXT    O N N 233 
HIS H      H N N 234 
HIS H2     H N N 235 
HIS HA     H N N 236 
HIS HB2    H N N 237 
HIS HB3    H N N 238 
HIS HD1    H N N 239 
HIS HD2    H N N 240 
HIS HE1    H N N 241 
HIS HE2    H N N 242 
HIS HXT    H N N 243 
HOH O      O N N 244 
HOH H1     H N N 245 
HOH H2     H N N 246 
ILE N      N N N 247 
ILE CA     C N S 248 
ILE C      C N N 249 
ILE O      O N N 250 
ILE CB     C N S 251 
ILE CG1    C N N 252 
ILE CG2    C N N 253 
ILE CD1    C N N 254 
ILE OXT    O N N 255 
ILE H      H N N 256 
ILE H2     H N N 257 
ILE HA     H N N 258 
ILE HB     H N N 259 
ILE HG12   H N N 260 
ILE HG13   H N N 261 
ILE HG21   H N N 262 
ILE HG22   H N N 263 
ILE HG23   H N N 264 
ILE HD11   H N N 265 
ILE HD12   H N N 266 
ILE HD13   H N N 267 
ILE HXT    H N N 268 
LEU N      N N N 269 
LEU CA     C N S 270 
LEU C      C N N 271 
LEU O      O N N 272 
LEU CB     C N N 273 
LEU CG     C N N 274 
LEU CD1    C N N 275 
LEU CD2    C N N 276 
LEU OXT    O N N 277 
LEU H      H N N 278 
LEU H2     H N N 279 
LEU HA     H N N 280 
LEU HB2    H N N 281 
LEU HB3    H N N 282 
LEU HG     H N N 283 
LEU HD11   H N N 284 
LEU HD12   H N N 285 
LEU HD13   H N N 286 
LEU HD21   H N N 287 
LEU HD22   H N N 288 
LEU HD23   H N N 289 
LEU HXT    H N N 290 
LYS N      N N N 291 
LYS CA     C N S 292 
LYS C      C N N 293 
LYS O      O N N 294 
LYS CB     C N N 295 
LYS CG     C N N 296 
LYS CD     C N N 297 
LYS CE     C N N 298 
LYS NZ     N N N 299 
LYS OXT    O N N 300 
LYS H      H N N 301 
LYS H2     H N N 302 
LYS HA     H N N 303 
LYS HB2    H N N 304 
LYS HB3    H N N 305 
LYS HG2    H N N 306 
LYS HG3    H N N 307 
LYS HD2    H N N 308 
LYS HD3    H N N 309 
LYS HE2    H N N 310 
LYS HE3    H N N 311 
LYS HZ1    H N N 312 
LYS HZ2    H N N 313 
LYS HZ3    H N N 314 
LYS HXT    H N N 315 
MES O1     O N N 316 
MES C2     C N N 317 
MES C3     C N N 318 
MES N4     N N N 319 
MES C5     C N N 320 
MES C6     C N N 321 
MES C7     C N N 322 
MES C8     C N N 323 
MES S      S N N 324 
MES O1S    O N N 325 
MES O2S    O N N 326 
MES O3S    O N N 327 
MES H21    H N N 328 
MES H22    H N N 329 
MES H31    H N N 330 
MES H32    H N N 331 
MES HN4    H N N 332 
MES H51    H N N 333 
MES H52    H N N 334 
MES H61    H N N 335 
MES H62    H N N 336 
MES H71    H N N 337 
MES H72    H N N 338 
MES H81    H N N 339 
MES H82    H N N 340 
MET N      N N N 341 
MET CA     C N S 342 
MET C      C N N 343 
MET O      O N N 344 
MET CB     C N N 345 
MET CG     C N N 346 
MET SD     S N N 347 
MET CE     C N N 348 
MET OXT    O N N 349 
MET H      H N N 350 
MET H2     H N N 351 
MET HA     H N N 352 
MET HB2    H N N 353 
MET HB3    H N N 354 
MET HG2    H N N 355 
MET HG3    H N N 356 
MET HE1    H N N 357 
MET HE2    H N N 358 
MET HE3    H N N 359 
MET HXT    H N N 360 
PHE N      N N N 361 
PHE CA     C N S 362 
PHE C      C N N 363 
PHE O      O N N 364 
PHE CB     C N N 365 
PHE CG     C Y N 366 
PHE CD1    C Y N 367 
PHE CD2    C Y N 368 
PHE CE1    C Y N 369 
PHE CE2    C Y N 370 
PHE CZ     C Y N 371 
PHE OXT    O N N 372 
PHE H      H N N 373 
PHE H2     H N N 374 
PHE HA     H N N 375 
PHE HB2    H N N 376 
PHE HB3    H N N 377 
PHE HD1    H N N 378 
PHE HD2    H N N 379 
PHE HE1    H N N 380 
PHE HE2    H N N 381 
PHE HZ     H N N 382 
PHE HXT    H N N 383 
PRO N      N N N 384 
PRO CA     C N S 385 
PRO C      C N N 386 
PRO O      O N N 387 
PRO CB     C N N 388 
PRO CG     C N N 389 
PRO CD     C N N 390 
PRO OXT    O N N 391 
PRO H      H N N 392 
PRO HA     H N N 393 
PRO HB2    H N N 394 
PRO HB3    H N N 395 
PRO HG2    H N N 396 
PRO HG3    H N N 397 
PRO HD2    H N N 398 
PRO HD3    H N N 399 
PRO HXT    H N N 400 
SER N      N N N 401 
SER CA     C N S 402 
SER C      C N N 403 
SER O      O N N 404 
SER CB     C N N 405 
SER OG     O N N 406 
SER OXT    O N N 407 
SER H      H N N 408 
SER H2     H N N 409 
SER HA     H N N 410 
SER HB2    H N N 411 
SER HB3    H N N 412 
SER HG     H N N 413 
SER HXT    H N N 414 
THR N      N N N 415 
THR CA     C N S 416 
THR C      C N N 417 
THR O      O N N 418 
THR CB     C N R 419 
THR OG1    O N N 420 
THR CG2    C N N 421 
THR OXT    O N N 422 
THR H      H N N 423 
THR H2     H N N 424 
THR HA     H N N 425 
THR HB     H N N 426 
THR HG1    H N N 427 
THR HG21   H N N 428 
THR HG22   H N N 429 
THR HG23   H N N 430 
THR HXT    H N N 431 
TRP N      N N N 432 
TRP CA     C N S 433 
TRP C      C N N 434 
TRP O      O N N 435 
TRP CB     C N N 436 
TRP CG     C Y N 437 
TRP CD1    C Y N 438 
TRP CD2    C Y N 439 
TRP NE1    N Y N 440 
TRP CE2    C Y N 441 
TRP CE3    C Y N 442 
TRP CZ2    C Y N 443 
TRP CZ3    C Y N 444 
TRP CH2    C Y N 445 
TRP OXT    O N N 446 
TRP H      H N N 447 
TRP H2     H N N 448 
TRP HA     H N N 449 
TRP HB2    H N N 450 
TRP HB3    H N N 451 
TRP HD1    H N N 452 
TRP HE1    H N N 453 
TRP HE3    H N N 454 
TRP HZ2    H N N 455 
TRP HZ3    H N N 456 
TRP HH2    H N N 457 
TRP HXT    H N N 458 
TYR N      N N N 459 
TYR CA     C N S 460 
TYR C      C N N 461 
TYR O      O N N 462 
TYR CB     C N N 463 
TYR CG     C Y N 464 
TYR CD1    C Y N 465 
TYR CD2    C Y N 466 
TYR CE1    C Y N 467 
TYR CE2    C Y N 468 
TYR CZ     C Y N 469 
TYR OH     O N N 470 
TYR OXT    O N N 471 
TYR H      H N N 472 
TYR H2     H N N 473 
TYR HA     H N N 474 
TYR HB2    H N N 475 
TYR HB3    H N N 476 
TYR HD1    H N N 477 
TYR HD2    H N N 478 
TYR HE1    H N N 479 
TYR HE2    H N N 480 
TYR HH     H N N 481 
TYR HXT    H N N 482 
VAL N      N N N 483 
VAL CA     C N S 484 
VAL C      C N N 485 
VAL O      O N N 486 
VAL CB     C N N 487 
VAL CG1    C N N 488 
VAL CG2    C N N 489 
VAL OXT    O N N 490 
VAL H      H N N 491 
VAL H2     H N N 492 
VAL HA     H N N 493 
VAL HB     H N N 494 
VAL HG11   H N N 495 
VAL HG12   H N N 496 
VAL HG13   H N N 497 
VAL HG21   H N N 498 
VAL HG22   H N N 499 
VAL HG23   H N N 500 
VAL HXT    H N N 501 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
CYS N     CA     sing N N 70  
CYS N     H      sing N N 71  
CYS N     H2     sing N N 72  
CYS CA    C      sing N N 73  
CYS CA    CB     sing N N 74  
CYS CA    HA     sing N N 75  
CYS C     O      doub N N 76  
CYS C     OXT    sing N N 77  
CYS CB    SG     sing N N 78  
CYS CB    HB2    sing N N 79  
CYS CB    HB3    sing N N 80  
CYS SG    HG     sing N N 81  
CYS OXT   HXT    sing N N 82  
FAD PA    O1A    doub N N 83  
FAD PA    O2A    sing N N 84  
FAD PA    O5B    sing N N 85  
FAD PA    O3P    sing N N 86  
FAD O2A   HOA2   sing N N 87  
FAD O5B   C5B    sing N N 88  
FAD C5B   C4B    sing N N 89  
FAD C5B   H51A   sing N N 90  
FAD C5B   H52A   sing N N 91  
FAD C4B   O4B    sing N N 92  
FAD C4B   C3B    sing N N 93  
FAD C4B   H4B    sing N N 94  
FAD O4B   C1B    sing N N 95  
FAD C3B   O3B    sing N N 96  
FAD C3B   C2B    sing N N 97  
FAD C3B   H3B    sing N N 98  
FAD O3B   HO3A   sing N N 99  
FAD C2B   O2B    sing N N 100 
FAD C2B   C1B    sing N N 101 
FAD C2B   H2B    sing N N 102 
FAD O2B   HO2A   sing N N 103 
FAD C1B   N9A    sing N N 104 
FAD C1B   H1B    sing N N 105 
FAD N9A   C8A    sing Y N 106 
FAD N9A   C4A    sing Y N 107 
FAD C8A   N7A    doub Y N 108 
FAD C8A   H8A    sing N N 109 
FAD N7A   C5A    sing Y N 110 
FAD C5A   C6A    sing Y N 111 
FAD C5A   C4A    doub Y N 112 
FAD C6A   N6A    sing N N 113 
FAD C6A   N1A    doub Y N 114 
FAD N6A   H61A   sing N N 115 
FAD N6A   H62A   sing N N 116 
FAD N1A   C2A    sing Y N 117 
FAD C2A   N3A    doub Y N 118 
FAD C2A   H2A    sing N N 119 
FAD N3A   C4A    sing Y N 120 
FAD N1    C2     sing N N 121 
FAD N1    C10    doub N N 122 
FAD C2    O2     doub N N 123 
FAD C2    N3     sing N N 124 
FAD N3    C4     sing N N 125 
FAD N3    HN3    sing N N 126 
FAD C4    O4     doub N N 127 
FAD C4    C4X    sing N N 128 
FAD C4X   N5     doub N N 129 
FAD C4X   C10    sing N N 130 
FAD N5    C5X    sing N N 131 
FAD C5X   C6     doub Y N 132 
FAD C5X   C9A    sing Y N 133 
FAD C6    C7     sing Y N 134 
FAD C6    H6     sing N N 135 
FAD C7    C7M    sing N N 136 
FAD C7    C8     doub Y N 137 
FAD C7M   HM71   sing N N 138 
FAD C7M   HM72   sing N N 139 
FAD C7M   HM73   sing N N 140 
FAD C8    C8M    sing N N 141 
FAD C8    C9     sing Y N 142 
FAD C8M   HM81   sing N N 143 
FAD C8M   HM82   sing N N 144 
FAD C8M   HM83   sing N N 145 
FAD C9    C9A    doub Y N 146 
FAD C9    H9     sing N N 147 
FAD C9A   N10    sing N N 148 
FAD N10   C10    sing N N 149 
FAD N10   "C1'"  sing N N 150 
FAD "C1'" "C2'"  sing N N 151 
FAD "C1'" "H1'1" sing N N 152 
FAD "C1'" "H1'2" sing N N 153 
FAD "C2'" "O2'"  sing N N 154 
FAD "C2'" "C3'"  sing N N 155 
FAD "C2'" "H2'"  sing N N 156 
FAD "O2'" "HO2'" sing N N 157 
FAD "C3'" "O3'"  sing N N 158 
FAD "C3'" "C4'"  sing N N 159 
FAD "C3'" "H3'"  sing N N 160 
FAD "O3'" "HO3'" sing N N 161 
FAD "C4'" "O4'"  sing N N 162 
FAD "C4'" "C5'"  sing N N 163 
FAD "C4'" "H4'"  sing N N 164 
FAD "O4'" "HO4'" sing N N 165 
FAD "C5'" "O5'"  sing N N 166 
FAD "C5'" "H5'1" sing N N 167 
FAD "C5'" "H5'2" sing N N 168 
FAD "O5'" P      sing N N 169 
FAD P     O1P    doub N N 170 
FAD P     O2P    sing N N 171 
FAD P     O3P    sing N N 172 
FAD O2P   HOP2   sing N N 173 
GLN N     CA     sing N N 174 
GLN N     H      sing N N 175 
GLN N     H2     sing N N 176 
GLN CA    C      sing N N 177 
GLN CA    CB     sing N N 178 
GLN CA    HA     sing N N 179 
GLN C     O      doub N N 180 
GLN C     OXT    sing N N 181 
GLN CB    CG     sing N N 182 
GLN CB    HB2    sing N N 183 
GLN CB    HB3    sing N N 184 
GLN CG    CD     sing N N 185 
GLN CG    HG2    sing N N 186 
GLN CG    HG3    sing N N 187 
GLN CD    OE1    doub N N 188 
GLN CD    NE2    sing N N 189 
GLN NE2   HE21   sing N N 190 
GLN NE2   HE22   sing N N 191 
GLN OXT   HXT    sing N N 192 
GLU N     CA     sing N N 193 
GLU N     H      sing N N 194 
GLU N     H2     sing N N 195 
GLU CA    C      sing N N 196 
GLU CA    CB     sing N N 197 
GLU CA    HA     sing N N 198 
GLU C     O      doub N N 199 
GLU C     OXT    sing N N 200 
GLU CB    CG     sing N N 201 
GLU CB    HB2    sing N N 202 
GLU CB    HB3    sing N N 203 
GLU CG    CD     sing N N 204 
GLU CG    HG2    sing N N 205 
GLU CG    HG3    sing N N 206 
GLU CD    OE1    doub N N 207 
GLU CD    OE2    sing N N 208 
GLU OE2   HE2    sing N N 209 
GLU OXT   HXT    sing N N 210 
GLY N     CA     sing N N 211 
GLY N     H      sing N N 212 
GLY N     H2     sing N N 213 
GLY CA    C      sing N N 214 
GLY CA    HA2    sing N N 215 
GLY CA    HA3    sing N N 216 
GLY C     O      doub N N 217 
GLY C     OXT    sing N N 218 
GLY OXT   HXT    sing N N 219 
HIS N     CA     sing N N 220 
HIS N     H      sing N N 221 
HIS N     H2     sing N N 222 
HIS CA    C      sing N N 223 
HIS CA    CB     sing N N 224 
HIS CA    HA     sing N N 225 
HIS C     O      doub N N 226 
HIS C     OXT    sing N N 227 
HIS CB    CG     sing N N 228 
HIS CB    HB2    sing N N 229 
HIS CB    HB3    sing N N 230 
HIS CG    ND1    sing Y N 231 
HIS CG    CD2    doub Y N 232 
HIS ND1   CE1    doub Y N 233 
HIS ND1   HD1    sing N N 234 
HIS CD2   NE2    sing Y N 235 
HIS CD2   HD2    sing N N 236 
HIS CE1   NE2    sing Y N 237 
HIS CE1   HE1    sing N N 238 
HIS NE2   HE2    sing N N 239 
HIS OXT   HXT    sing N N 240 
HOH O     H1     sing N N 241 
HOH O     H2     sing N N 242 
ILE N     CA     sing N N 243 
ILE N     H      sing N N 244 
ILE N     H2     sing N N 245 
ILE CA    C      sing N N 246 
ILE CA    CB     sing N N 247 
ILE CA    HA     sing N N 248 
ILE C     O      doub N N 249 
ILE C     OXT    sing N N 250 
ILE CB    CG1    sing N N 251 
ILE CB    CG2    sing N N 252 
ILE CB    HB     sing N N 253 
ILE CG1   CD1    sing N N 254 
ILE CG1   HG12   sing N N 255 
ILE CG1   HG13   sing N N 256 
ILE CG2   HG21   sing N N 257 
ILE CG2   HG22   sing N N 258 
ILE CG2   HG23   sing N N 259 
ILE CD1   HD11   sing N N 260 
ILE CD1   HD12   sing N N 261 
ILE CD1   HD13   sing N N 262 
ILE OXT   HXT    sing N N 263 
LEU N     CA     sing N N 264 
LEU N     H      sing N N 265 
LEU N     H2     sing N N 266 
LEU CA    C      sing N N 267 
LEU CA    CB     sing N N 268 
LEU CA    HA     sing N N 269 
LEU C     O      doub N N 270 
LEU C     OXT    sing N N 271 
LEU CB    CG     sing N N 272 
LEU CB    HB2    sing N N 273 
LEU CB    HB3    sing N N 274 
LEU CG    CD1    sing N N 275 
LEU CG    CD2    sing N N 276 
LEU CG    HG     sing N N 277 
LEU CD1   HD11   sing N N 278 
LEU CD1   HD12   sing N N 279 
LEU CD1   HD13   sing N N 280 
LEU CD2   HD21   sing N N 281 
LEU CD2   HD22   sing N N 282 
LEU CD2   HD23   sing N N 283 
LEU OXT   HXT    sing N N 284 
LYS N     CA     sing N N 285 
LYS N     H      sing N N 286 
LYS N     H2     sing N N 287 
LYS CA    C      sing N N 288 
LYS CA    CB     sing N N 289 
LYS CA    HA     sing N N 290 
LYS C     O      doub N N 291 
LYS C     OXT    sing N N 292 
LYS CB    CG     sing N N 293 
LYS CB    HB2    sing N N 294 
LYS CB    HB3    sing N N 295 
LYS CG    CD     sing N N 296 
LYS CG    HG2    sing N N 297 
LYS CG    HG3    sing N N 298 
LYS CD    CE     sing N N 299 
LYS CD    HD2    sing N N 300 
LYS CD    HD3    sing N N 301 
LYS CE    NZ     sing N N 302 
LYS CE    HE2    sing N N 303 
LYS CE    HE3    sing N N 304 
LYS NZ    HZ1    sing N N 305 
LYS NZ    HZ2    sing N N 306 
LYS NZ    HZ3    sing N N 307 
LYS OXT   HXT    sing N N 308 
MES O1    C2     sing N N 309 
MES O1    C6     sing N N 310 
MES C2    C3     sing N N 311 
MES C2    H21    sing N N 312 
MES C2    H22    sing N N 313 
MES C3    N4     sing N N 314 
MES C3    H31    sing N N 315 
MES C3    H32    sing N N 316 
MES N4    C5     sing N N 317 
MES N4    C7     sing N N 318 
MES N4    HN4    sing N N 319 
MES C5    C6     sing N N 320 
MES C5    H51    sing N N 321 
MES C5    H52    sing N N 322 
MES C6    H61    sing N N 323 
MES C6    H62    sing N N 324 
MES C7    C8     sing N N 325 
MES C7    H71    sing N N 326 
MES C7    H72    sing N N 327 
MES C8    S      sing N N 328 
MES C8    H81    sing N N 329 
MES C8    H82    sing N N 330 
MES S     O1S    doub N N 331 
MES S     O2S    doub N N 332 
MES S     O3S    sing N N 333 
MET N     CA     sing N N 334 
MET N     H      sing N N 335 
MET N     H2     sing N N 336 
MET CA    C      sing N N 337 
MET CA    CB     sing N N 338 
MET CA    HA     sing N N 339 
MET C     O      doub N N 340 
MET C     OXT    sing N N 341 
MET CB    CG     sing N N 342 
MET CB    HB2    sing N N 343 
MET CB    HB3    sing N N 344 
MET CG    SD     sing N N 345 
MET CG    HG2    sing N N 346 
MET CG    HG3    sing N N 347 
MET SD    CE     sing N N 348 
MET CE    HE1    sing N N 349 
MET CE    HE2    sing N N 350 
MET CE    HE3    sing N N 351 
MET OXT   HXT    sing N N 352 
PHE N     CA     sing N N 353 
PHE N     H      sing N N 354 
PHE N     H2     sing N N 355 
PHE CA    C      sing N N 356 
PHE CA    CB     sing N N 357 
PHE CA    HA     sing N N 358 
PHE C     O      doub N N 359 
PHE C     OXT    sing N N 360 
PHE CB    CG     sing N N 361 
PHE CB    HB2    sing N N 362 
PHE CB    HB3    sing N N 363 
PHE CG    CD1    doub Y N 364 
PHE CG    CD2    sing Y N 365 
PHE CD1   CE1    sing Y N 366 
PHE CD1   HD1    sing N N 367 
PHE CD2   CE2    doub Y N 368 
PHE CD2   HD2    sing N N 369 
PHE CE1   CZ     doub Y N 370 
PHE CE1   HE1    sing N N 371 
PHE CE2   CZ     sing Y N 372 
PHE CE2   HE2    sing N N 373 
PHE CZ    HZ     sing N N 374 
PHE OXT   HXT    sing N N 375 
PRO N     CA     sing N N 376 
PRO N     CD     sing N N 377 
PRO N     H      sing N N 378 
PRO CA    C      sing N N 379 
PRO CA    CB     sing N N 380 
PRO CA    HA     sing N N 381 
PRO C     O      doub N N 382 
PRO C     OXT    sing N N 383 
PRO CB    CG     sing N N 384 
PRO CB    HB2    sing N N 385 
PRO CB    HB3    sing N N 386 
PRO CG    CD     sing N N 387 
PRO CG    HG2    sing N N 388 
PRO CG    HG3    sing N N 389 
PRO CD    HD2    sing N N 390 
PRO CD    HD3    sing N N 391 
PRO OXT   HXT    sing N N 392 
SER N     CA     sing N N 393 
SER N     H      sing N N 394 
SER N     H2     sing N N 395 
SER CA    C      sing N N 396 
SER CA    CB     sing N N 397 
SER CA    HA     sing N N 398 
SER C     O      doub N N 399 
SER C     OXT    sing N N 400 
SER CB    OG     sing N N 401 
SER CB    HB2    sing N N 402 
SER CB    HB3    sing N N 403 
SER OG    HG     sing N N 404 
SER OXT   HXT    sing N N 405 
THR N     CA     sing N N 406 
THR N     H      sing N N 407 
THR N     H2     sing N N 408 
THR CA    C      sing N N 409 
THR CA    CB     sing N N 410 
THR CA    HA     sing N N 411 
THR C     O      doub N N 412 
THR C     OXT    sing N N 413 
THR CB    OG1    sing N N 414 
THR CB    CG2    sing N N 415 
THR CB    HB     sing N N 416 
THR OG1   HG1    sing N N 417 
THR CG2   HG21   sing N N 418 
THR CG2   HG22   sing N N 419 
THR CG2   HG23   sing N N 420 
THR OXT   HXT    sing N N 421 
TRP N     CA     sing N N 422 
TRP N     H      sing N N 423 
TRP N     H2     sing N N 424 
TRP CA    C      sing N N 425 
TRP CA    CB     sing N N 426 
TRP CA    HA     sing N N 427 
TRP C     O      doub N N 428 
TRP C     OXT    sing N N 429 
TRP CB    CG     sing N N 430 
TRP CB    HB2    sing N N 431 
TRP CB    HB3    sing N N 432 
TRP CG    CD1    doub Y N 433 
TRP CG    CD2    sing Y N 434 
TRP CD1   NE1    sing Y N 435 
TRP CD1   HD1    sing N N 436 
TRP CD2   CE2    doub Y N 437 
TRP CD2   CE3    sing Y N 438 
TRP NE1   CE2    sing Y N 439 
TRP NE1   HE1    sing N N 440 
TRP CE2   CZ2    sing Y N 441 
TRP CE3   CZ3    doub Y N 442 
TRP CE3   HE3    sing N N 443 
TRP CZ2   CH2    doub Y N 444 
TRP CZ2   HZ2    sing N N 445 
TRP CZ3   CH2    sing Y N 446 
TRP CZ3   HZ3    sing N N 447 
TRP CH2   HH2    sing N N 448 
TRP OXT   HXT    sing N N 449 
TYR N     CA     sing N N 450 
TYR N     H      sing N N 451 
TYR N     H2     sing N N 452 
TYR CA    C      sing N N 453 
TYR CA    CB     sing N N 454 
TYR CA    HA     sing N N 455 
TYR C     O      doub N N 456 
TYR C     OXT    sing N N 457 
TYR CB    CG     sing N N 458 
TYR CB    HB2    sing N N 459 
TYR CB    HB3    sing N N 460 
TYR CG    CD1    doub Y N 461 
TYR CG    CD2    sing Y N 462 
TYR CD1   CE1    sing Y N 463 
TYR CD1   HD1    sing N N 464 
TYR CD2   CE2    doub Y N 465 
TYR CD2   HD2    sing N N 466 
TYR CE1   CZ     doub Y N 467 
TYR CE1   HE1    sing N N 468 
TYR CE2   CZ     sing Y N 469 
TYR CE2   HE2    sing N N 470 
TYR CZ    OH     sing N N 471 
TYR OH    HH     sing N N 472 
TYR OXT   HXT    sing N N 473 
VAL N     CA     sing N N 474 
VAL N     H      sing N N 475 
VAL N     H2     sing N N 476 
VAL CA    C      sing N N 477 
VAL CA    CB     sing N N 478 
VAL CA    HA     sing N N 479 
VAL C     O      doub N N 480 
VAL C     OXT    sing N N 481 
VAL CB    CG1    sing N N 482 
VAL CB    CG2    sing N N 483 
VAL CB    HB     sing N N 484 
VAL CG1   HG11   sing N N 485 
VAL CG1   HG12   sing N N 486 
VAL CG1   HG13   sing N N 487 
VAL CG2   HG21   sing N N 488 
VAL CG2   HG22   sing N N 489 
VAL CG2   HG23   sing N N 490 
VAL OXT   HXT    sing N N 491 
# 
_pdbx_audit_support.funding_organization   'Japan Science and Technology' 
_pdbx_audit_support.country                Japan 
_pdbx_audit_support.grant_number           JPMJSP2138 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   5h59 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9KKC 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.016866 
_atom_sites.fract_transf_matrix[1][2]   0.009738 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.019475 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.005341 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
C 6  6  0.6650  0.0000 
D 1  1  0.6670  0.0000 
H 1  1  -0.3740 0.0000 
N 7  7  0.9360  0.0000 
O 8  8  0.5810  0.0000 
P 15 15 0.5130  0.0000 
S 16 16 0.2847  0.0000 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    N N      . SER A 1 1   ? 36.357  -6.125  20.759  1    52.285 ? 1009 SER A N      1 ? 
ATOM   2    C CA     . SER A 1 1   ? 37.028  -7.446  20.831  1    44.444 ? 1009 SER A CA     1 ? 
ATOM   3    C C      . SER A 1 1   ? 36.027  -8.526  21.26   1    35.803 ? 1009 SER A C      1 ? 
ATOM   4    O O      . SER A 1 1   ? 34.999  -8.28   21.889  1    35.888 ? 1009 SER A O      1 ? 
ATOM   5    C CB     . SER A 1 1   ? 38.265  -7.378  21.698  1    43.504 ? 1009 SER A CB     1 ? 
ATOM   6    O OG     . SER A 1 1   ? 37.942  -7.171  23.063  1    46.228 ? 1009 SER A OG     1 ? 
ATOM   7    H HA     . SER A 1 1   ? 37.346  -7.698  19.821  1    44.226 ? 1009 SER A HA     1 c 
ATOM   8    H HB2    . SER A 1 1   ? 38.83   -8.307  21.596  1    44.558 ? 1009 SER A HB2    1 c 
ATOM   9    H HB3    . SER A 1 1   ? 38.897  -6.557  21.356  1    44.69  ? 1009 SER A HB3    1 c 
ATOM   10   H HG     . SER A 1 1   ? 37.505  -6.308  23.165  1    44.737 ? 1009 SER A HG     1 ? 
ATOM   11   N N      . LYS A 1 2   ? 36.325  -9.738  20.823  1    27.939 ? 1010 LYS A N      1 ? 
ATOM   12   C CA     . LYS A 1 2   ? 35.396  -10.848 20.868  1    24.865 ? 1010 LYS A CA     1 ? 
ATOM   13   C C      . LYS A 1 2   ? 35.361  -11.463 22.266  1    21.78  ? 1010 LYS A C      1 ? 
ATOM   14   O O      . LYS A 1 2   ? 36.349  -11.444 23.012  1    26.513 ? 1010 LYS A O      1 ? 
ATOM   15   C CB     . LYS A 1 2   ? 35.769  -11.855 19.781  1    21.26  ? 1010 LYS A CB     1 ? 
ATOM   16   C CG     . LYS A 1 2   ? 35.685  -11.346 18.351  1    20.744 ? 1010 LYS A CG     1 ? 
ATOM   17   C CD     . LYS A 1 2   ? 36.184  -12.428 17.395  1    21.505 ? 1010 LYS A CD     1 ? 
ATOM   18   C CE     . LYS A 1 2   ? 36.22   -12.129 15.924  1    22.803 ? 1010 LYS A CE     1 ? 
ATOM   19   N NZ     . LYS A 1 2   ? 34.881  -11.986 15.345  1    27.578 ? 1010 LYS A NZ     1 ? 
ATOM   20   H H      . LYS A 1 2   ? 37.286  -9.91   20.476  1    27.977 ? 1010 LYS A H      1 ? 
ATOM   21   H HA     . LYS A 1 2   ? 34.4    -10.461 20.642  1    24.204 ? 1010 LYS A HA     1 c 
ATOM   22   H HB2    . LYS A 1 2   ? 36.79   -12.196 19.963  1    21.874 ? 1010 LYS A HB2    1 c 
ATOM   23   H HB3    . LYS A 1 2   ? 35.112  -12.721 19.874  1    21.845 ? 1010 LYS A HB3    1 c 
ATOM   24   H HG2    . LYS A 1 2   ? 34.648  -11.094 18.116  1    21.018 ? 1010 LYS A HG2    1 c 
ATOM   25   H HG3    . LYS A 1 2   ? 36.3    -10.45  18.249  1    21.019 ? 1010 LYS A HG3    1 c 
ATOM   26   H HD2    . LYS A 1 2   ? 37.191  -12.706 17.71   1    21.607 ? 1010 LYS A HD2    1 c 
ATOM   27   H HD3    . LYS A 1 2   ? 35.562  -13.311 17.545  1    21.574 ? 1010 LYS A HD3    1 c 
ATOM   28   H HE2    . LYS A 1 2   ? 36.778  -11.206 15.757  1    23.504 ? 1010 LYS A HE2    1 c 
ATOM   29   H HE3    . LYS A 1 2   ? 36.737  -12.942 15.41   1    23.504 ? 1010 LYS A HE3    1 c 
ATOM   30   H HZ1    . LYS A 1 2   ? 34.428  -11.108 15.656  1    24.889 ? 1010 LYS A HZ1    1 ? 
ATOM   31   H HZ2    . LYS A 1 2   ? 34.993  -11.957 14.32   1    26.282 ? 1010 LYS A HZ2    1 ? 
ATOM   32   H HZ3    . LYS A 1 2   ? 34.281  -12.792 15.578  1    25.072 ? 1010 LYS A HZ3    1 ? 
ATOM   33   N N      . VAL A 1 3   ? 34.206  -12.03  22.61   1    19.575 ? 1011 VAL A N      1 ? 
ATOM   34   C CA     . VAL A 1 3   ? 33.932  -12.56  23.947  1    19.744 ? 1011 VAL A CA     1 ? 
ATOM   35   C C      . VAL A 1 3   ? 34.529  -13.959 24.057  1    19.859 ? 1011 VAL A C      1 ? 
ATOM   36   O O      . VAL A 1 3   ? 34.308  -14.816 23.199  1    18.671 ? 1011 VAL A O      1 ? 
ATOM   37   C CB     . VAL A 1 3   ? 32.415  -12.613 24.197  1    20.641 ? 1011 VAL A CB     1 ? 
ATOM   38   C CG1    . VAL A 1 3   ? 32.088  -13.305 25.524  1    20.971 ? 1011 VAL A CG1    1 ? 
ATOM   39   C CG2    . VAL A 1 3   ? 31.792  -11.224 24.105  1    19.858 ? 1011 VAL A CG2    1 ? 
ATOM   40   H H      . VAL A 1 3   ? 33.497  -12.196 21.887  1    20.131 ? 1011 VAL A H      1 ? 
ATOM   41   H HA     . VAL A 1 3   ? 34.398  -11.909 24.691  1    19.905 ? 1011 VAL A HA     1 c 
ATOM   42   H HB     . VAL A 1 3   ? 31.983  -13.218 23.398  1    20.392 ? 1011 VAL A HB     1 c 
ATOM   43   H HG11   . VAL A 1 3   ? 31.024  -13.191 25.741  1    20.875 ? 1011 VAL A HG11   1 c 
ATOM   44   H HG12   . VAL A 1 3   ? 32.33   -14.367 25.454  1    20.888 ? 1011 VAL A HG12   1 c 
ATOM   45   H HG13   . VAL A 1 3   ? 32.671  -12.85  26.328  1    20.85  ? 1011 VAL A HG13   1 c 
ATOM   46   H HG21   . VAL A 1 3   ? 31.961  -10.813 23.108  1    20.098 ? 1011 VAL A HG21   1 c 
ATOM   47   H HG22   . VAL A 1 3   ? 30.718  -11.294 24.291  1    20.199 ? 1011 VAL A HG22   1 c 
ATOM   48   H HG23   . VAL A 1 3   ? 32.247  -10.569 24.85   1    20.093 ? 1011 VAL A HG23   1 c 
ATOM   49   N N      . SER A 1 4   ? 35.252  -14.214 25.15   1    19.865 ? 1012 SER A N      1 ? 
ATOM   50   C CA     . SER A 1 4   ? 35.782  -15.539 25.41   1    18.951 ? 1012 SER A CA     1 ? 
ATOM   51   C C      . SER A 1 4   ? 34.643  -16.534 25.605  1    18.326 ? 1012 SER A C      1 ? 
ATOM   52   O O      . SER A 1 4   ? 33.706  -16.272 26.363  1    21.622 ? 1012 SER A O      1 ? 
ATOM   53   C CB     . SER A 1 4   ? 36.673  -15.558 26.624  1    20.651 ? 1012 SER A CB     1 ? 
ATOM   54   O OG     . SER A 1 4   ? 37.899  -14.886 26.337  1    23.438 ? 1012 SER A OG     1 ? 
ATOM   55   H H      . SER A 1 4   ? 35.469  -13.448 25.802  1    22.292 ? 1012 SER A H      1 ? 
ATOM   56   H HA     . SER A 1 4   ? 36.368  -15.851 24.543  1    19.267 ? 1012 SER A HA     1 c 
ATOM   57   H HB2    . SER A 1 4   ? 36.168  -15.062 27.455  1    20.886 ? 1012 SER A HB2    1 c 
ATOM   58   H HB3    . SER A 1 4   ? 36.879  -16.592 26.91   1    20.874 ? 1012 SER A HB3    1 c 
ATOM   59   H HG     . SER A 1 4   ? 38.465  -14.93  27.125  1    22.491 ? 1012 SER A HG     1 ? 
ATOM   60   N N      . VAL A 1 5   ? 34.725  -17.676 24.932  1    16.856 ? 1013 VAL A N      1 ? 
ATOM   61   C CA     . VAL A 1 5   ? 33.741  -18.738 25.048  1    16.051 ? 1013 VAL A CA     1 ? 
ATOM   62   C C      . VAL A 1 5   ? 34.475  -20.004 25.457  1    16.48  ? 1013 VAL A C      1 ? 
ATOM   63   O O      . VAL A 1 5   ? 35.65   -20.199 25.126  1    18.219 ? 1013 VAL A O      1 ? 
ATOM   64   C CB     . VAL A 1 5   ? 32.958  -18.973 23.744  1    15.182 ? 1013 VAL A CB     1 ? 
ATOM   65   C CG1    . VAL A 1 5   ? 32.044  -17.802 23.472  1    16.235 ? 1013 VAL A CG1    1 ? 
ATOM   66   C CG2    . VAL A 1 5   ? 33.895  -19.232 22.55   1    16.512 ? 1013 VAL A CG2    1 ? 
ATOM   67   H H      . VAL A 1 5   ? 35.566  -17.859 24.347  1    15.327 ? 1013 VAL A H      1 ? 
ATOM   68   H HA     . VAL A 1 5   ? 33.034  -18.475 25.837  1    16.161 ? 1013 VAL A HA     1 c 
ATOM   69   H HB     . VAL A 1 5   ? 32.341  -19.86  23.893  1    15.735 ? 1013 VAL A HB     1 c 
ATOM   70   H HG11   . VAL A 1 5   ? 31.346  -17.684 24.303  1    15.938 ? 1013 VAL A HG11   1 c 
ATOM   71   H HG12   . VAL A 1 5   ? 32.638  -16.892 23.366  1    15.933 ? 1013 VAL A HG12   1 c 
ATOM   72   H HG13   . VAL A 1 5   ? 31.486  -17.981 22.552  1    15.925 ? 1013 VAL A HG13   1 c 
ATOM   73   H HG21   . VAL A 1 5   ? 34.504  -20.117 22.746  1    16.147 ? 1013 VAL A HG21   1 c 
ATOM   74   H HG22   . VAL A 1 5   ? 33.3    -19.394 21.649  1    16.145 ? 1013 VAL A HG22   1 c 
ATOM   75   H HG23   . VAL A 1 5   ? 34.546  -18.368 22.403  1    16.176 ? 1013 VAL A HG23   1 c 
ATOM   76   N N      . ALA A 1 6   ? 33.76   -20.88  26.154  1    15.501 ? 1014 ALA A N      1 ? 
ATOM   77   C CA     . ALA A 1 6   ? 34.301  -22.142 26.613  1    16.494 ? 1014 ALA A CA     1 ? 
ATOM   78   C C      . ALA A 1 6   ? 33.176  -23.163 26.632  1    15.939 ? 1014 ALA A C      1 ? 
ATOM   79   O O      . ALA A 1 6   ? 32.003  -22.784 26.781  1    15.82  ? 1014 ALA A O      1 ? 
ATOM   80   C CB     . ALA A 1 6   ? 34.89   -21.998 28.022  1    16.955 ? 1014 ALA A CB     1 ? 
ATOM   81   H H      . ALA A 1 6   ? 32.819  -20.597 26.48   1    17.22  ? 1014 ALA A H      1 ? 
ATOM   82   H HA     . ALA A 1 6   ? 35.073  -22.473 25.916  1    16.29  ? 1014 ALA A HA     1 c 
ATOM   83   H HB1    . ALA A 1 6   ? 35.7    -21.267 28.008  1    16.82  ? 1014 ALA A HB1    1 c 
ATOM   84   H HB2    . ALA A 1 6   ? 34.113  -21.663 28.712  1    16.82  ? 1014 ALA A HB2    1 c 
ATOM   85   H HB3    . ALA A 1 6   ? 35.278  -22.962 28.357  1    16.801 ? 1014 ALA A HB3    1 c 
ATOM   86   N N      . PRO A 1 7   ? 33.482  -24.463 26.506  1    15.992 ? 1015 PRO A N      1 ? 
ATOM   87   C CA     . PRO A 1 7   ? 34.822  -25.022 26.275  1    16.087 ? 1015 PRO A CA     1 ? 
ATOM   88   C C      . PRO A 1 7   ? 35.112  -25.211 24.798  1    17.222 ? 1015 PRO A C      1 ? 
ATOM   89   O O      . PRO A 1 7   ? 34.223  -25.61  24.035  1    16.153 ? 1015 PRO A O      1 ? 
ATOM   90   C CB     . PRO A 1 7   ? 34.738  -26.384 26.968  1    15.928 ? 1015 PRO A CB     1 ? 
ATOM   91   C CG     . PRO A 1 7   ? 33.285  -26.789 26.759  1    15.193 ? 1015 PRO A CG     1 ? 
ATOM   92   C CD     . PRO A 1 7   ? 32.479  -25.508 26.735  1    15.254 ? 1015 PRO A CD     1 ? 
ATOM   93   H HA     . PRO A 1 7   ? 35.584  -24.394 26.738  1    16.229 ? 1015 PRO A HA     1 c 
ATOM   94   H HB2    . PRO A 1 7   ? 35.417  -27.102 26.505  1    15.812 ? 1015 PRO A HB2    1 c 
ATOM   95   H HB3    . PRO A 1 7   ? 34.972  -26.298 28.031  1    15.803 ? 1015 PRO A HB3    1 c 
ATOM   96   H HG2    . PRO A 1 7   ? 33.169  -27.327 25.815  1    15.362 ? 1015 PRO A HG2    1 c 
ATOM   97   H HG3    . PRO A 1 7   ? 32.946  -27.435 27.571  1    15.362 ? 1015 PRO A HG3    1 c 
ATOM   98   H HD2    . PRO A 1 7   ? 31.743  -25.519 25.928  1    15.403 ? 1015 PRO A HD2    1 c 
ATOM   99   H HD3    . PRO A 1 7   ? 31.966  -25.347 27.686  1    15.403 ? 1015 PRO A HD3    1 c 
ATOM   100  N N      . LEU A 1 8   ? 36.345  -24.945 24.389  1    16.489 ? 1016 LEU A N      1 ? 
ATOM   101  C CA     . LEU A 1 8   ? 36.667  -24.998 22.971  1    16.979 ? 1016 LEU A CA     1 ? 
ATOM   102  C C      . LEU A 1 8   ? 36.601  -26.406 22.397  1    15.2   ? 1016 LEU A C      1 ? 
ATOM   103  O O      . LEU A 1 8   ? 36.531  -26.55  21.172  1    16.164 ? 1016 LEU A O      1 ? 
ATOM   104  C CB     . LEU A 1 8   ? 37.998  -24.301 22.708  1    21.416 ? 1016 LEU A CB     1 ? 
ATOM   105  C CG     . LEU A 1 8   ? 37.839  -22.764 22.712  1    24.586 ? 1016 LEU A CG     1 ? 
ATOM   106  C CD1    . LEU A 1 8   ? 39.157  -22.069 22.628  1    24.507 ? 1016 LEU A CD1    1 ? 
ATOM   107  C CD2    . LEU A 1 8   ? 36.864  -22.24  21.625  1    27.809 ? 1016 LEU A CD2    1 ? 
ATOM   108  H H      . LEU A 1 8   ? 37.055  -24.602 25.055  1    18.212 ? 1016 LEU A H      1 ? 
ATOM   109  H HA     . LEU A 1 8   ? 35.89   -24.431 22.459  1    17.357 ? 1016 LEU A HA     1 c 
ATOM   110  H HB2    . LEU A 1 8   ? 38.705  -24.587 23.489  1    20.961 ? 1016 LEU A HB2    1 c 
ATOM   111  H HB3    . LEU A 1 8   ? 38.373  -24.616 21.732  1    20.961 ? 1016 LEU A HB3    1 c 
ATOM   112  H HG     . LEU A 1 8   ? 37.405  -22.49  23.676  1    24.507 ? 1016 LEU A HG     1 c 
ATOM   113  H HD11   . LEU A 1 8   ? 39.663  -22.355 21.703  1    24.507 ? 1016 LEU A HD11   1 c 
ATOM   114  H HD12   . LEU A 1 8   ? 39.002  -20.988 22.637  1    24.507 ? 1016 LEU A HD12   1 c 
ATOM   115  H HD13   . LEU A 1 8   ? 39.776  -22.353 23.482  1    24.437 ? 1016 LEU A HD13   1 c 
ATOM   116  H HD21   . LEU A 1 8   ? 37.166  -22.622 20.648  1    26.833 ? 1016 LEU A HD21   1 c 
ATOM   117  H HD22   . LEU A 1 8   ? 35.85   -22.576 21.849  1    26.744 ? 1016 LEU A HD22   1 c 
ATOM   118  H HD23   . LEU A 1 8   ? 36.887  -21.148 21.612  1    26.753 ? 1016 LEU A HD23   1 c 
ATOM   119  N N      . HIS A 1 9   ? 36.508  -27.447 23.238  1    15.904 ? 1017 HIS A N      1 ? 
ATOM   120  C CA     . HIS A 1 9   ? 36.285  -28.784 22.71   1    16.731 ? 1017 HIS A CA     1 ? 
ATOM   121  C C      . HIS A 1 9   ? 34.953  -28.925 21.983  1    17.373 ? 1017 HIS A C      1 ? 
ATOM   122  O O      . HIS A 1 9   ? 34.774  -29.917 21.273  1    17.099 ? 1017 HIS A O      1 ? 
ATOM   123  C CB     . HIS A 1 9   ? 36.475  -29.875 23.78   1    16.984 ? 1017 HIS A CB     1 ? 
ATOM   124  C CG     . HIS A 1 9   ? 35.407  -29.947 24.83   1    17.693 ? 1017 HIS A CG     1 ? 
ATOM   125  N ND1    . HIS A 1 9   ? 35.649  -29.658 26.157  1    17.926 ? 1017 HIS A ND1    1 ? 
ATOM   126  C CD2    . HIS A 1 9   ? 34.11   -30.332 24.775  1    18.741 ? 1017 HIS A CD2    1 ? 
ATOM   127  C CE1    . HIS A 1 9   ? 34.547  -29.853 26.871  1    18.372 ? 1017 HIS A CE1    1 ? 
ATOM   128  N NE2    . HIS A 1 9   ? 33.592  -30.249 26.049  1    20.814 ? 1017 HIS A NE2    1 ? 
ATOM   129  H H      . HIS A 1 9   ? 36.73   -27.316 24.234  1    16.652 ? 1017 HIS A H      1 ? 
ATOM   130  H HA     . HIS A 1 9   ? 37.074  -28.942 21.972  1    16.721 ? 1017 HIS A HA     1 c 
ATOM   131  H HB2    . HIS A 1 9   ? 36.535  -30.843 23.278  1    17.084 ? 1017 HIS A HB2    1 c 
ATOM   132  H HB3    . HIS A 1 9   ? 37.436  -29.712 24.271  1    17.084 ? 1017 HIS A HB3    1 c 
ATOM   133  H HD1    . HIS A 1 9   ? 36.505  -29.349 26.533  1    18.767 ? 1017 HIS A HD1    1 ? 
ATOM   134  H HD2    . HIS A 1 9   ? 33.565  -30.644 23.89   1    18.929 ? 1017 HIS A HD2    1 c 
ATOM   135  H HE1    . HIS A 1 9   ? 34.44   -29.675 27.935  1    18.791 ? 1017 HIS A HE1    1 c 
ATOM   136  H HE2    . HIS A 1 9   ? 32.63   -30.466 26.313  1    22.029 ? 1017 HIS A HE2    1 ? 
ATOM   137  N N      . LEU A 1 10  ? 34.043  -27.957 22.107  1    16.81  ? 1018 LEU A N      1 ? 
ATOM   138  C CA     . LEU A 1 10  ? 32.832  -27.988 21.289  1    18.306 ? 1018 LEU A CA     1 ? 
ATOM   139  C C      . LEU A 1 10  ? 33.121  -27.836 19.795  1    17.593 ? 1018 LEU A C      1 ? 
ATOM   140  O O      . LEU A 1 10  ? 32.23   -28.086 18.977  1    17.58  ? 1018 LEU A O      1 ? 
ATOM   141  C CB     . LEU A 1 10  ? 31.828  -26.925 21.745  1    17.732 ? 1018 LEU A CB     1 ? 
ATOM   142  C CG     . LEU A 1 10  ? 31.266  -27.117 23.152  1    17.813 ? 1018 LEU A CG     1 ? 
ATOM   143  C CD1    . LEU A 1 10  ? 30.214  -26.058 23.443  1    20.155 ? 1018 LEU A CD1    1 ? 
ATOM   144  C CD2    . LEU A 1 10  ? 30.69   -28.487 23.391  1    17.767 ? 1018 LEU A CD2    1 ? 
ATOM   145  H H      . LEU A 1 10  ? 34.223  -27.135 22.717  1    18.228 ? 1018 LEU A H      1 ? 
ATOM   146  H HA     . LEU A 1 10  ? 32.376  -28.97  21.427  1    17.781 ? 1018 LEU A HA     1 c 
ATOM   147  H HB2    . LEU A 1 10  ? 32.318  -25.95  21.698  1    17.874 ? 1018 LEU A HB2    1 c 
ATOM   148  H HB3    . LEU A 1 10  ? 30.995  -26.917 21.038  1    17.874 ? 1018 LEU A HB3    1 c 
ATOM   149  H HG     . LEU A 1 10  ? 32.084  -26.975 23.861  1    18.179 ? 1018 LEU A HG     1 c 
ATOM   150  H HD11   . LEU A 1 10  ? 29.817  -26.204 24.45   1    19.448 ? 1018 LEU A HD11   1 c 
ATOM   151  H HD12   . LEU A 1 10  ? 30.664  -25.066 23.372  1    19.403 ? 1018 LEU A HD12   1 c 
ATOM   152  H HD13   . LEU A 1 10  ? 29.402  -26.141 22.718  1    19.409 ? 1018 LEU A HD13   1 c 
ATOM   153  H HD21   . LEU A 1 10  ? 31.481  -29.235 23.318  1    17.782 ? 1018 LEU A HD21   1 c 
ATOM   154  H HD22   . LEU A 1 10  ? 30.245  -28.526 24.387  1    17.78  ? 1018 LEU A HD22   1 c 
ATOM   155  H HD23   . LEU A 1 10  ? 29.922  -28.695 22.643  1    17.779 ? 1018 LEU A HD23   1 c 
ATOM   156  N N      . GLU A 1 11  ? 34.323  -27.398 19.425  1    16.16  ? 1019 GLU A N      1 ? 
ATOM   157  C CA     . GLU A 1 11  ? 34.708  -27.3   18.026  1    16.205 ? 1019 GLU A CA     1 ? 
ATOM   158  C C      . GLU A 1 11  ? 35.243  -28.613 17.468  1    18.901 ? 1019 GLU A C      1 ? 
ATOM   159  O O      . GLU A 1 11  ? 35.451  -28.711 16.255  1    18.042 ? 1019 GLU A O      1 ? 
ATOM   160  C CB     . GLU A 1 11  ? 35.782  -26.221 17.856  1    15.883 ? 1019 GLU A CB     1 ? 
ATOM   161  C CG     . GLU A 1 11  ? 35.352  -24.834 18.303  1    16.838 ? 1019 GLU A CG     1 ? 
ATOM   162  C CD     . GLU A 1 11  ? 34.216  -24.269 17.476  1    15.407 ? 1019 GLU A CD     1 ? 
ATOM   163  O OE1    . GLU A 1 11  ? 34.189  -24.504 16.248  1    16.379 ? 1019 GLU A OE1    1 ? 
ATOM   164  O OE2    . GLU A 1 11  ? 33.348  -23.573 18.054  1    19.386 ? 1019 GLU A OE2    1 ? 
ATOM   165  H H      . GLU A 1 11  ? 34.936  -27.041 20.175  1    15.508 ? 1019 GLU A H      1 ? 
ATOM   166  H HA     . GLU A 1 11  ? 33.828  -27.01  17.447  1    16.588 ? 1019 GLU A HA     1 c 
ATOM   167  H HB2    . GLU A 1 11  ? 36.664  -26.514 18.428  1    16.241 ? 1019 GLU A HB2    1 c 
ATOM   168  H HB3    . GLU A 1 11  ? 36.07   -26.177 16.803  1    16.176 ? 1019 GLU A HB3    1 c 
ATOM   169  H HG2    . GLU A 1 11  ? 35.038  -24.878 19.347  1    16.352 ? 1019 GLU A HG2    1 c 
ATOM   170  H HG3    . GLU A 1 11  ? 36.204  -24.156 18.239  1    16.38  ? 1019 GLU A HG3    1 c 
ATOM   171  N N      . SER A 1 12  ? 35.473  -29.622 18.315  1    18.656 ? 1020 SER A N      1 ? 
ATOM   172  C CA     . SER A 1 12  ? 36.196  -30.808 17.867  1    19.745 ? 1020 SER A CA     1 ? 
ATOM   173  C C      . SER A 1 12  ? 35.344  -31.734 16.998  1    20.551 ? 1020 SER A C      1 ? 
ATOM   174  O O      . SER A 1 12  ? 35.866  -32.361 16.072  1    20.25  ? 1020 SER A O      1 ? 
ATOM   175  C CB     . SER A 1 12  ? 36.754  -31.578 19.054  1    20.474 ? 1020 SER A CB     1 ? 
ATOM   176  O OG     . SER A 1 12  ? 37.623  -30.761 19.822  1    22.873 ? 1020 SER A OG     1 ? 
ATOM   177  H H      . SER A 1 12  ? 35.299  -29.507 19.327  1    19.999 ? 1020 SER A H      1 ? 
ATOM   178  H HA     . SER A 1 12  ? 37.04   -30.47  17.262  1    19.792 ? 1020 SER A HA     1 c 
ATOM   179  H HB2    . SER A 1 12  ? 35.929  -31.923 19.681  1    20.846 ? 1020 SER A HB2    1 c 
ATOM   180  H HB3    . SER A 1 12  ? 37.3    -32.452 18.694  1    20.846 ? 1020 SER A HB3    1 c 
ATOM   181  H HG     . SER A 1 12  ? 38.458  -30.622 19.311  1    21.746 ? 1020 SER A HG     1 ? 
ATOM   182  N N      . ALA A 1 13  ? 34.051  -31.861 17.299  1    20.468 ? 1021 ALA A N      1 ? 
ATOM   183  C CA     . ALA A 1 13  ? 33.202  -32.778 16.556  1    21.639 ? 1021 ALA A CA     1 ? 
ATOM   184  C C      . ALA A 1 13  ? 33.181  -32.424 15.071  1    21.425 ? 1021 ALA A C      1 ? 
ATOM   185  O O      . ALA A 1 13  ? 33.128  -31.256 14.698  1    20.454 ? 1021 ALA A O      1 ? 
ATOM   186  C CB     . ALA A 1 13  ? 31.779  -32.758 17.104  1    22.861 ? 1021 ALA A CB     1 ? 
ATOM   187  H H      . ALA A 1 13  ? 33.635  -31.324 18.084  1    20.713 ? 1021 ALA A H      1 ? 
ATOM   188  H HA     . ALA A 1 13  ? 33.613  -33.785 16.662  1    21.589 ? 1021 ALA A HA     1 c 
ATOM   189  H HB1    . ALA A 1 13  ? 31.369  -31.748 17.027  1    22.511 ? 1021 ALA A HB1    1 c 
ATOM   190  H HB2    . ALA A 1 13  ? 31.154  -33.445 16.529  1    22.543 ? 1021 ALA A HB2    1 c 
ATOM   191  H HB3    . ALA A 1 13  ? 31.783  -33.066 18.152  1    22.464 ? 1021 ALA A HB3    1 c 
ATOM   192  N N      . LYS A 1 14  ? 33.229  -33.456 14.225  1    23.683 ? 1022 LYS A N      1 ? 
ATOM   193  C CA     . LYS A 1 14  ? 33.247  -33.235 12.786  1    29.267 ? 1022 LYS A CA     1 ? 
ATOM   194  C C      . LYS A 1 14  ? 31.862  -33.306 12.156  1    25.574 ? 1022 LYS A C      1 ? 
ATOM   195  O O      . LYS A 1 14  ? 31.707  -32.946 10.987  1    23.842 ? 1022 LYS A O      1 ? 
ATOM   196  C CB     . LYS A 1 14  ? 34.182  -34.246 12.107  1    41.79  ? 1022 LYS A CB     1 ? 
ATOM   197  C CG     . LYS A 1 14  ? 34.253  -35.667 12.712  1    50.957 ? 1022 LYS A CG     1 ? 
ATOM   198  C CD     . LYS A 1 14  ? 34.838  -36.712 11.764  1    61.881 ? 1022 LYS A CD     1 ? 
ATOM   199  C CE     . LYS A 1 14  ? 34.212  -36.578 10.4    1    69.492 ? 1022 LYS A CE     1 ? 
ATOM   200  N NZ     . LYS A 1 14  ? 34.038  -37.877 9.76    1    75.968 ? 1022 LYS A NZ     1 ? 
ATOM   201  H H      . LYS A 1 14  ? 33.348  -34.412 14.601  1    22.409 ? 1022 LYS A H      1 ? 
ATOM   202  H HA     . LYS A 1 14  ? 33.651  -32.237 12.602  1    29.15  ? 1022 LYS A HA     1 c 
ATOM   203  H HB2    . LYS A 1 14  ? 33.879  -34.332 11.063  1    40.433 ? 1022 LYS A HB2    1 c 
ATOM   204  H HB3    . LYS A 1 14  ? 35.191  -33.829 12.116  1    40.345 ? 1022 LYS A HB3    1 c 
ATOM   205  H HG2    . LYS A 1 14  ? 34.861  -35.629 13.618  1    50.547 ? 1022 LYS A HG2    1 c 
ATOM   206  H HG3    . LYS A 1 14  ? 33.245  -35.973 12.999  1    50.798 ? 1022 LYS A HG3    1 c 
ATOM   207  H HD2    . LYS A 1 14  ? 35.918  -36.57  11.683  1    60.891 ? 1022 LYS A HD2    1 c 
ATOM   208  H HD3    . LYS A 1 14  ? 34.643  -37.712 12.156  1    60.985 ? 1022 LYS A HD3    1 c 
ATOM   209  H HE2    . LYS A 1 14  ? 33.231  -36.107 10.49   1    68.487 ? 1022 LYS A HE2    1 c 
ATOM   210  H HE3    . LYS A 1 14  ? 34.839  -35.947 9.766   1    69.019 ? 1022 LYS A HE3    1 c 
ATOM   211  H HZ1    . LYS A 1 14  ? 34.927  -38.235 9.418   1    74.033 ? 1022 LYS A HZ1    1 ? 
ATOM   212  H HZ2    . LYS A 1 14  ? 33.648  -38.526 10.443  1    77.031 ? 1022 LYS A HZ2    1 ? 
ATOM   213  H HZ3    . LYS A 1 14  ? 33.394  -37.769 8.98    1    75.807 ? 1022 LYS A HZ3    1 ? 
ATOM   214  N N      . GLU A 1 15  ? 30.869  -33.768 12.898  1    23.495 ? 1023 GLU A N      1 ? 
ATOM   215  C CA     . GLU A 1 15  ? 29.508  -33.899 12.416  1    26.589 ? 1023 GLU A CA     1 ? 
ATOM   216  C C      . GLU A 1 15  ? 28.574  -33.323 13.466  1    22.333 ? 1023 GLU A C      1 ? 
ATOM   217  O O      . GLU A 1 15  ? 28.896  -33.36  14.655  1    20.814 ? 1023 GLU A O      1 ? 
ATOM   218  C CB     . GLU A 1 15  ? 29.087  -35.379 12.412  1    27.283 ? 1023 GLU A CB     1 ? 
ATOM   219  C CG     . GLU A 1 15  ? 29.826  -36.293 11.43   1    37.555 ? 1023 GLU A CG     1 ? 
ATOM   220  C CD     . GLU A 1 15  ? 29.521  -36.011 9.955   1    49.063 ? 1023 GLU A CD     1 ? 
ATOM   221  O OE1    . GLU A 1 15  ? 28.387  -36.312 9.493   1    49.066 ? 1023 GLU A OE1    1 ? 
ATOM   222  O OE2    . GLU A 1 15  ? 30.409  -35.461 9.252   1    49.777 ? 1023 GLU A OE2    1 ? 
ATOM   223  H H      . GLU A 1 15  ? 31.066  -34.08  13.862  1    24.794 ? 1023 GLU A H      1 ? 
ATOM   224  H HA     . GLU A 1 15  ? 29.387  -33.4   11.453  1    25.287 ? 1023 GLU A HA     1 c 
ATOM   225  H HB2    . GLU A 1 15  ? 29.23   -35.781 13.417  1    29.107 ? 1023 GLU A HB2    1 c 
ATOM   226  H HB3    . GLU A 1 15  ? 28.021  -35.434 12.185  1    29.07  ? 1023 GLU A HB3    1 c 
ATOM   227  H HG2    . GLU A 1 15  ? 30.901  -36.186 11.587  1    37.128 ? 1023 GLU A HG2    1 c 
ATOM   228  H HG3    . GLU A 1 15  ? 29.563  -37.331 11.645  1    37.128 ? 1023 GLU A HG3    1 c 
ATOM   229  N N      . PRO A 1 16  ? 27.415  -32.787 13.065  1    21.938 ? 1024 PRO A N      1 ? 
ATOM   230  C CA     . PRO A 1 16  ? 26.497  -32.23  14.048  1    22.266 ? 1024 PRO A CA     1 ? 
ATOM   231  C C      . PRO A 1 16  ? 25.832  -33.345 14.837  1    19.12  ? 1024 PRO A C      1 ? 
ATOM   232  O O      . PRO A 1 16  ? 25.567  -34.43  14.307  1    20.079 ? 1024 PRO A O      1 ? 
ATOM   233  C CB     . PRO A 1 16  ? 25.468  -31.473 13.198  1    18.412 ? 1024 PRO A CB     1 ? 
ATOM   234  C CG     . PRO A 1 16  ? 25.473  -32.241 11.893  1    21.232 ? 1024 PRO A CG     1 ? 
ATOM   235  C CD     . PRO A 1 16  ? 26.902  -32.655 11.686  1    24.759 ? 1024 PRO A CD     1 ? 
ATOM   236  H HA     . PRO A 1 16  ? 27.029  -31.55  14.714  1    20.915 ? 1024 PRO A HA     1 c 
ATOM   237  H HB2    . PRO A 1 16  ? 24.48   -31.496 13.664  1    19.776 ? 1024 PRO A HB2    1 c 
ATOM   238  H HB3    . PRO A 1 16  ? 25.772  -30.435 13.045  1    19.78  ? 1024 PRO A HB3    1 c 
ATOM   239  H HG2    . PRO A 1 16  ? 24.825  -33.117 11.955  1    21.276 ? 1024 PRO A HG2    1 c 
ATOM   240  H HG3    . PRO A 1 16  ? 25.134  -31.611 11.07   1    21.214 ? 1024 PRO A HG3    1 c 
ATOM   241  H HD2    . PRO A 1 16  ? 26.967  -33.607 11.156  1    23.318 ? 1024 PRO A HD2    1 c 
ATOM   242  H HD3    . PRO A 1 16  ? 27.461  -31.895 11.136  1    23.318 ? 1024 PRO A HD3    1 c 
ATOM   243  N N      . PRO A 1 17  ? 25.55   -33.121 16.122  1    20.211 ? 1025 PRO A N      1 ? 
ATOM   244  C CA     . PRO A 1 17  ? 24.768  -34.09  16.872  1    20.653 ? 1025 PRO A CA     1 ? 
ATOM   245  C C      . PRO A 1 17  ? 23.36   -34.185 16.31   1    18.084 ? 1025 PRO A C      1 ? 
ATOM   246  O O      . PRO A 1 17  ? 22.792  -33.186 15.867  1    18.443 ? 1025 PRO A O      1 ? 
ATOM   247  C CB     . PRO A 1 17  ? 24.756  -33.526 18.297  1    20.551 ? 1025 PRO A CB     1 ? 
ATOM   248  C CG     . PRO A 1 17  ? 25.802  -32.45  18.322  1    21.958 ? 1025 PRO A CG     1 ? 
ATOM   249  C CD     . PRO A 1 17  ? 25.868  -31.927 16.925  1    21.124 ? 1025 PRO A CD     1 ? 
ATOM   250  H HA     . PRO A 1 17  ? 25.254  -35.068 16.845  1    20.074 ? 1025 PRO A HA     1 c 
ATOM   251  H HB2    . PRO A 1 17  ? 23.774  -33.115 18.54   1    20.899 ? 1025 PRO A HB2    1 c 
ATOM   252  H HB3    . PRO A 1 17  ? 24.99   -34.306 19.023  1    21.089 ? 1025 PRO A HB3    1 c 
ATOM   253  H HG2    . PRO A 1 17  ? 25.525  -31.654 19.015  1    21.473 ? 1025 PRO A HG2    1 c 
ATOM   254  H HG3    . PRO A 1 17  ? 26.765  -32.858 18.623  1    21.758 ? 1025 PRO A HG3    1 c 
ATOM   255  H HD2    . PRO A 1 17  ? 25.132  -31.138 16.757  1    21.095 ? 1025 PRO A HD2    1 c 
ATOM   256  H HD3    . PRO A 1 17  ? 26.865  -31.552 16.689  1    21.099 ? 1025 PRO A HD3    1 c 
ATOM   257  N N      . LEU A 1 18  ? 22.793  -35.391 16.321  1    17.618 ? 1026 LEU A N      1 ? 
ATOM   258  C CA     . LEU A 1 18  ? 21.43   -35.592 15.853  1    17.66  ? 1026 LEU A CA     1 ? 
ATOM   259  C C      . LEU A 1 18  ? 20.744  -36.618 16.742  1    17.518 ? 1026 LEU A C      1 ? 
ATOM   260  O O      . LEU A 1 18  ? 21.267  -37.721 16.931  1    20.136 ? 1026 LEU A O      1 ? 
ATOM   261  C CB     . LEU A 1 18  ? 21.382  -36.078 14.405  1    19.207 ? 1026 LEU A CB     1 ? 
ATOM   262  C CG     . LEU A 1 18  ? 21.772  -35.072 13.32   1    20.825 ? 1026 LEU A CG     1 ? 
ATOM   263  C CD1    . LEU A 1 18  ? 21.982  -35.802 11.983  1    25.132 ? 1026 LEU A CD1    1 ? 
ATOM   264  C CD2    . LEU A 1 18  ? 20.752  -33.949 13.206  1    19.781 ? 1026 LEU A CD2    1 ? 
ATOM   265  H H      . LEU A 1 18  ? 23.323  -36.212 16.65   1    18.192 ? 1026 LEU A H      1 ? 
ATOM   266  H HA     . LEU A 1 18  ? 20.893  -34.646 15.933  1    17.864 ? 1026 LEU A HA     1 c 
ATOM   267  H HB2    . LEU A 1 18  ? 22.04   -36.945 14.318  1    19.193 ? 1026 LEU A HB2    1 c 
ATOM   268  H HB3    . LEU A 1 18  ? 20.367  -36.426 14.199  1    19.193 ? 1026 LEU A HB3    1 c 
ATOM   269  H HG     . LEU A 1 18  ? 22.726  -34.625 13.606  1    21.017 ? 1026 LEU A HG     1 c 
ATOM   270  H HD11   . LEU A 1 18  ? 21.053  -36.292 11.684  1    23.882 ? 1026 LEU A HD11   1 c 
ATOM   271  H HD12   . LEU A 1 18  ? 22.276  -35.083 11.216  1    23.882 ? 1026 LEU A HD12   1 c 
ATOM   272  H HD13   . LEU A 1 18  ? 22.766  -36.552 12.097  1    23.942 ? 1026 LEU A HD13   1 c 
ATOM   273  H HD21   . LEU A 1 18  ? 20.709  -33.397 14.147  1    20.073 ? 1026 LEU A HD21   1 c 
ATOM   274  H HD22   . LEU A 1 18  ? 21.043  -33.271 12.4    1    20.073 ? 1026 LEU A HD22   1 c 
ATOM   275  H HD23   . LEU A 1 18  ? 19.769  -34.37  12.987  1    20.095 ? 1026 LEU A HD23   1 c 
ATOM   276  N N      . ASN A 1 19  ? 19.559  -36.265 17.257  1    15.915 ? 1027 ASN A N      1 ? 
ATOM   277  C CA     . ASN A 1 19  ? 18.716  -37.21  17.977  1    17.33  ? 1027 ASN A CA     1 ? 
ATOM   278  C C      . ASN A 1 19  ? 19.416  -37.813 19.19   1    16.171 ? 1027 ASN A C      1 ? 
ATOM   279  O O      . ASN A 1 19  ? 19.175  -38.97  19.546  1    16.436 ? 1027 ASN A O      1 ? 
ATOM   280  C CB     . ASN A 1 19  ? 18.165  -38.288 17.05   1    18.898 ? 1027 ASN A CB     1 ? 
ATOM   281  C CG     . ASN A 1 19  ? 17.325  -37.704 15.939  1    21.97  ? 1027 ASN A CG     1 ? 
ATOM   282  O OD1    . ASN A 1 19  ? 17.7    -37.865 14.769  1    18.606 ? 1027 ASN A OD1    1 ? 
ATOM   283  N ND2    . ASN A 1 19  ? 16.26   -36.966 16.235  1    27.388 ? 1027 ASN A ND2    1 ? 
ATOM   284  H H      . ASN A 1 19  ? 19.269  -35.277 17.189  1    17.452 ? 1027 ASN A H      1 ? 
ATOM   285  H HA     . ASN A 1 19  ? 17.855  -36.651 18.35   1    17.108 ? 1027 ASN A HA     1 c 
ATOM   286  H HB2    . ASN A 1 19  ? 18.995  -38.848 16.615  1    19.296 ? 1027 ASN A HB2    1 c 
ATOM   287  H HB3    . ASN A 1 19  ? 17.555  -38.984 17.63   1    19.179 ? 1027 ASN A HB3    1 c 
ATOM   288  H HD21   . ASN A 1 19  ? 15.81   -36.443 15.48   1    25.672 ? 1027 ASN A HD21   1 ? 
ATOM   289  H HD22   . ASN A 1 19  ? 15.939  -36.873 17.199  1    24.629 ? 1027 ASN A HD22   1 ? 
ATOM   290  N N      . THR A 1 20  ? 20.247  -37.002 19.848  1    16.211 ? 1028 THR A N      1 ? 
ATOM   291  C CA     . THR A 1 20  ? 20.929  -37.427 21.06   1    15.755 ? 1028 THR A CA     1 ? 
ATOM   292  C C      . THR A 1 20  ? 19.929  -37.892 22.111  1    15.088 ? 1028 THR A C      1 ? 
ATOM   293  O O      . THR A 1 20  ? 20.142  -38.909 22.781  1    15.789 ? 1028 THR A O      1 ? 
ATOM   294  C CB     . THR A 1 20  ? 21.733  -36.241 21.582  1    16.011 ? 1028 THR A CB     1 ? 
ATOM   295  O OG1    . THR A 1 20  ? 22.484  -35.707 20.488  1    14.251 ? 1028 THR A OG1    1 ? 
ATOM   296  C CG2    . THR A 1 20  ? 22.664  -36.663 22.718  1    15.47  ? 1028 THR A CG2    1 ? 
ATOM   297  H H      . THR A 1 20  ? 20.441  -36.047 19.51   1    16.555 ? 1028 THR A H      1 ? 
ATOM   298  H HA     . THR A 1 20  ? 21.609  -38.245 20.818  1    15.764 ? 1028 THR A HA     1 c 
ATOM   299  H HB     . THR A 1 20  ? 21.05   -35.476 21.956  1    15.525 ? 1028 THR A HB     1 c 
ATOM   300  H HG1    . THR A 1 20  ? 23.345  -36.138 20.393  1    15.222 ? 1028 THR A HG1    1 ? 
ATOM   301  H HG21   . THR A 1 20  ? 23.257  -35.804 23.04   1    15.618 ? 1028 THR A HG21   1 c 
ATOM   302  H HG22   . THR A 1 20  ? 22.072  -37.031 23.558  1    15.616 ? 1028 THR A HG22   1 c 
ATOM   303  H HG23   . THR A 1 20  ? 23.331  -37.453 22.368  1    15.621 ? 1028 THR A HG23   1 c 
ATOM   304  N N      . TYR A 1 21  ? 18.835  -37.151 22.262  1    16.004 ? 1029 TYR A N      1 ? 
ATOM   305  C CA     . TYR A 1 21  ? 17.725  -37.553 23.111  1    16.36  ? 1029 TYR A CA     1 ? 
ATOM   306  C C      . TYR A 1 21  ? 16.491  -37.726 22.243  1    16.611 ? 1029 TYR A C      1 ? 
ATOM   307  O O      . TYR A 1 21  ? 16.215  -36.918 21.35   1    15.937 ? 1029 TYR A O      1 ? 
ATOM   308  C CB     . TYR A 1 21  ? 17.475  -36.543 24.237  1    16.922 ? 1029 TYR A CB     1 ? 
ATOM   309  C CG     . TYR A 1 21  ? 18.567  -36.607 25.27   1    16.627 ? 1029 TYR A CG     1 ? 
ATOM   310  C CD1    . TYR A 1 21  ? 19.744  -35.895 25.097  1    18.594 ? 1029 TYR A CD1    1 ? 
ATOM   311  C CD2    . TYR A 1 21  ? 18.445  -37.435 26.377  1    17.134 ? 1029 TYR A CD2    1 ? 
ATOM   312  C CE1    . TYR A 1 21  ? 20.767  -35.975 26.02   1    17.979 ? 1029 TYR A CE1    1 ? 
ATOM   313  C CE2    . TYR A 1 21  ? 19.458  -37.52  27.314  1    16.852 ? 1029 TYR A CE2    1 ? 
ATOM   314  C CZ     . TYR A 1 21  ? 20.619  -36.787 27.134  1    18.711 ? 1029 TYR A CZ     1 ? 
ATOM   315  O OH     . TYR A 1 21  ? 21.654  -36.852 28.029  1    18.144 ? 1029 TYR A OH     1 ? 
ATOM   316  H H      . TYR A 1 21  ? 18.696  -36.335 21.637  1    15.128 ? 1029 TYR A H      1 ? 
ATOM   317  H HA     . TYR A 1 21  ? 17.967  -38.517 23.562  1    16.448 ? 1029 TYR A HA     1 c 
ATOM   318  H HB2    . TYR A 1 21  ? 17.436  -35.538 23.812  1    16.734 ? 1029 TYR A HB2    1 c 
ATOM   319  H HB3    . TYR A 1 21  ? 16.516  -36.766 24.709  1    16.734 ? 1029 TYR A HB3    1 c 
ATOM   320  H HD1    . TYR A 1 21  ? 19.861  -35.258 24.227  1    17.999 ? 1029 TYR A HD1    1 c 
ATOM   321  H HD2    . TYR A 1 21  ? 17.536  -38.008 26.521  1    17.002 ? 1029 TYR A HD2    1 c 
ATOM   322  H HE1    . TYR A 1 21  ? 21.675  -35.402 25.881  1    18.235 ? 1029 TYR A HE1    1 c 
ATOM   323  H HE2    . TYR A 1 21  ? 19.346  -38.159 28.184  1    17.312 ? 1029 TYR A HE2    1 c 
ATOM   324  H HH     . TYR A 1 21  ? 21.493  -37.509 28.697  1    19.556 ? 1029 TYR A HH     1 ? 
ATOM   325  N N      . LYS A 1 22  ? 15.771  -38.812 22.513  1    19.56  ? 1030 LYS A N      1 ? 
ATOM   326  C CA     . LYS A 1 22  ? 14.616  -39.201 21.73   1    21.894 ? 1030 LYS A CA     1 ? 
ATOM   327  C C      . LYS A 1 22  ? 13.356  -39.03  22.558  1    21.264 ? 1030 LYS A C      1 ? 
ATOM   328  O O      . LYS A 1 22  ? 13.415  -38.961 23.793  1    21.304 ? 1030 LYS A O      1 ? 
ATOM   329  C CB     . LYS A 1 22  ? 14.78   -40.668 21.333  1    24.795 ? 1030 LYS A CB     1 ? 
ATOM   330  C CG     . LYS A 1 22  ? 15.885  -40.923 20.316  1    25.096 ? 1030 LYS A CG     1 ? 
ATOM   331  C CD     . LYS A 1 22  ? 16.182  -42.411 20.194  1    31.203 ? 1030 LYS A CD     1 ? 
ATOM   332  C CE     . LYS A 1 22  ? 17.509  -42.799 19.64   1    37.346 ? 1030 LYS A CE     1 ? 
ATOM   333  N NZ     . LYS A 1 22  ? 17.56   -44.263 19.423  1    38.831 ? 1030 LYS A NZ     1 ? 
ATOM   334  H H      . LYS A 1 22  ? 16.187  -39.523 23.133  1    19.895 ? 1030 LYS A H      1 ? 
ATOM   335  H HA     . LYS A 1 22  ? 14.561  -38.572 20.841  1    21.727 ? 1030 LYS A HA     1 c 
ATOM   336  H HB2    . LYS A 1 22  ? 14.994  -41.254 22.23   1    24.196 ? 1030 LYS A HB2    1 c 
ATOM   337  H HB3    . LYS A 1 22  ? 13.837  -41.028 20.918  1    24.196 ? 1030 LYS A HB3    1 c 
ATOM   338  H HG2    . LYS A 1 22  ? 15.573  -40.532 19.346  1    26.246 ? 1030 LYS A HG2    1 c 
ATOM   339  H HG3    . LYS A 1 22  ? 16.787  -40.395 20.63   1    26.246 ? 1030 LYS A HG3    1 c 
ATOM   340  H HD2    . LYS A 1 22  ? 16.083  -42.854 21.187  1    30.987 ? 1030 LYS A HD2    1 c 
ATOM   341  H HD3    . LYS A 1 22  ? 15.404  -42.858 19.571  1    30.969 ? 1030 LYS A HD3    1 c 
ATOM   342  H HE2    . LYS A 1 22  ? 17.658  -42.287 18.69   1    36.604 ? 1030 LYS A HE2    1 c 
ATOM   343  H HE3    . LYS A 1 22  ? 18.301  -42.508 20.332  1    36.537 ? 1030 LYS A HE3    1 c 
ATOM   344  H HZ1    . LYS A 1 22  ? 17.05   -44.526 18.572  1    36.361 ? 1030 LYS A HZ1    1 ? 
ATOM   345  H HZ2    . LYS A 1 22  ? 18.53   -44.556 19.315  1    37.374 ? 1030 LYS A HZ2    1 ? 
ATOM   346  H HZ3    . LYS A 1 22  ? 17.147  -44.754 20.225  1    37.637 ? 1030 LYS A HZ3    1 ? 
ATOM   347  N N      . PRO A 1 23  ? 12.179  -38.946 21.911  1    24.291 ? 1031 PRO A N      1 ? 
ATOM   348  C CA     . PRO A 1 23  ? 10.964  -38.583 22.641  1    23.398 ? 1031 PRO A CA     1 ? 
ATOM   349  C C      . PRO A 1 23  ? 10.609  -39.508 23.802  1    25.914 ? 1031 PRO A C      1 ? 
ATOM   350  O O      . PRO A 1 23  ? 10.05   -39.038 24.801  1    31.041 ? 1031 PRO A O      1 ? 
ATOM   351  C CB     . PRO A 1 23  ? 9.884   -38.591 21.556  1    22.306 ? 1031 PRO A CB     1 ? 
ATOM   352  C CG     . PRO A 1 23  ? 10.649  -38.229 20.317  1    22.232 ? 1031 PRO A CG     1 ? 
ATOM   353  C CD     . PRO A 1 23  ? 11.944  -38.976 20.458  1    22.92  ? 1031 PRO A CD     1 ? 
ATOM   354  H HA     . PRO A 1 23  ? 11.072  -37.566 23.022  1    23.71  ? 1031 PRO A HA     1 c 
ATOM   355  H HB2    . PRO A 1 23  ? 9.428   -39.579 21.463  1    22.518 ? 1031 PRO A HB2    1 c 
ATOM   356  H HB3    . PRO A 1 23  ? 9.108   -37.853 21.769  1    22.518 ? 1031 PRO A HB3    1 c 
ATOM   357  H HG2    . PRO A 1 23  ? 10.115  -38.546 19.419  1    22.397 ? 1031 PRO A HG2    1 c 
ATOM   358  H HG3    . PRO A 1 23  ? 10.826  -37.153 20.266  1    22.397 ? 1031 PRO A HG3    1 c 
ATOM   359  H HD2    . PRO A 1 23  ? 11.853  -40.003 20.099  1    23.062 ? 1031 PRO A HD2    1 c 
ATOM   360  H HD3    . PRO A 1 23  ? 12.751  -38.474 19.921  1    23.047 ? 1031 PRO A HD3    1 c 
ATOM   361  N N      . LYS A 1 24  ? 10.893  -40.796 23.712  1    26.887 ? 1032 LYS A N      1 ? 
ATOM   362  C CA     . LYS A 1 24  ? 10.524  -41.695 24.786  1    29.362 ? 1032 LYS A CA     1 ? 
ATOM   363  C C      . LYS A 1 24  ? 11.383  -41.493 26.041  1    30.181 ? 1032 LYS A C      1 ? 
ATOM   364  O O      . LYS A 1 24  ? 10.954  -41.867 27.141  1    28.421 ? 1032 LYS A O      1 ? 
ATOM   365  C CB     . LYS A 1 24  ? 10.723  -43.118 24.255  1    36.996 ? 1032 LYS A CB     1 ? 
ATOM   366  C CG     . LYS A 1 24  ? 9.843   -43.493 23.02   1    46.009 ? 1032 LYS A CG     1 ? 
ATOM   367  C CD     . LYS A 1 24  ? 8.425   -43.986 23.3    1    56.33  ? 1032 LYS A CD     1 ? 
ATOM   368  C CE     . LYS A 1 24  ? 8.437   -45.104 24.315  1    65.309 ? 1032 LYS A CE     1 ? 
ATOM   369  N NZ     . LYS A 1 24  ? 7.136   -45.732 24.553  1    69.303 ? 1032 LYS A NZ     1 ? 
ATOM   370  H H      . LYS A 1 24  ? 11.372  -41.168 22.868  1    26.457 ? 1032 LYS A H      1 ? 
ATOM   371  H HA     . LYS A 1 24  ? 9.473   -41.534 25.035  1    30.221 ? 1032 LYS A HA     1 c 
ATOM   372  H HB2    . LYS A 1 24  ? 11.772  -43.239 23.977  1    36.91  ? 1032 LYS A HB2    1 c 
ATOM   373  H HB3    . LYS A 1 24  ? 10.514  -43.823 25.061  1    37.168 ? 1032 LYS A HB3    1 c 
ATOM   374  H HG2    . LYS A 1 24  ? 9.776   -42.616 22.374  1    45.75  ? 1032 LYS A HG2    1 c 
ATOM   375  H HG3    . LYS A 1 24  ? 10.368  -44.268 22.457  1    45.87  ? 1032 LYS A HG3    1 c 
ATOM   376  H HD2    . LYS A 1 24  ? 7.822   -43.159 23.682  1    55.694 ? 1032 LYS A HD2    1 c 
ATOM   377  H HD3    . LYS A 1 24  ? 7.974   -44.345 22.372  1    55.694 ? 1032 LYS A HD3    1 c 
ATOM   378  H HE2    . LYS A 1 24  ? 9.135   -45.874 23.979  1    63.988 ? 1032 LYS A HE2    1 c 
ATOM   379  H HE3    . LYS A 1 24  ? 8.805   -44.717 25.267  1    63.574 ? 1032 LYS A HE3    1 c 
ATOM   380  H HZ1    . LYS A 1 24  ? 6.784   -46.137 23.688  1    67.134 ? 1032 LYS A HZ1    1 ? 
ATOM   381  H HZ2    . LYS A 1 24  ? 7.269   -46.468 25.242  1    67.503 ? 1032 LYS A HZ2    1 ? 
ATOM   382  H HZ3    . LYS A 1 24  ? 6.464   -45.058 24.912  1    64.63  ? 1032 LYS A HZ3    1 ? 
ATOM   383  N N      . GLU A 1 25  ? 12.585  -40.929 25.894  1    26.234 ? 1033 GLU A N      1 ? 
ATOM   384  C CA     . GLU A 1 25  ? 13.469  -40.66  27.024  1    25.517 ? 1033 GLU A CA     1 ? 
ATOM   385  C C      . GLU A 1 25  ? 14.136  -39.303 26.83   1    22.131 ? 1033 GLU A C      1 ? 
ATOM   386  O O      . GLU A 1 25  ? 15.322  -39.21  26.505  1    19.644 ? 1033 GLU A O      1 ? 
ATOM   387  C CB     . GLU A 1 25  ? 14.516  -41.754 27.216  1    30.101 ? 1033 GLU A CB     1 ? 
ATOM   388  C CG     . GLU A 1 25  ? 13.943  -43.174 27.2    1    37.459 ? 1033 GLU A CG     1 ? 
ATOM   389  C CD     . GLU A 1 25  ? 14.936  -44.319 27.412  1    45.212 ? 1033 GLU A CD     1 ? 
ATOM   390  O OE1    . GLU A 1 25  ? 15.838  -44.556 26.561  1    43.302 ? 1033 GLU A OE1    1 ? 
ATOM   391  O OE2    . GLU A 1 25  ? 14.796  -44.98  28.463  1    48.442 ? 1033 GLU A OE2    1 ? 
ATOM   392  H H      . GLU A 1 25  ? 12.883  -40.597 24.957  1    24.428 ? 1033 GLU A H      1 ? 
ATOM   393  H HA     . GLU A 1 25  ? 12.86   -40.615 27.929  1    25.726 ? 1033 GLU A HA     1 c 
ATOM   394  H HB2    . GLU A 1 25  ? 15.26   -41.676 26.422  1    30.311 ? 1033 GLU A HB2    1 c 
ATOM   395  H HB3    . GLU A 1 25  ? 15.027  -41.588 28.167  1    30.421 ? 1033 GLU A HB3    1 c 
ATOM   396  H HG2    . GLU A 1 25  ? 13.175  -43.245 27.974  1    37.194 ? 1033 GLU A HG2    1 c 
ATOM   397  H HG3    . GLU A 1 25  ? 13.444  -43.335 26.243  1    37.105 ? 1033 GLU A HG3    1 c 
ATOM   398  N N      . PRO A 1 26  ? 13.386  -38.213 27.027  1    17.665 ? 1034 PRO A N      1 ? 
ATOM   399  C CA     . PRO A 1 26  ? 13.942  -36.885 26.819  1    18.927 ? 1034 PRO A CA     1 ? 
ATOM   400  C C      . PRO A 1 26  ? 14.974  -36.538 27.879  1    18.812 ? 1034 PRO A C      1 ? 
ATOM   401  O O      . PRO A 1 26  ? 15.105  -37.213 28.905  1    19.412 ? 1034 PRO A O      1 ? 
ATOM   402  C CB     . PRO A 1 26  ? 12.733  -35.961 26.909  1    17.434 ? 1034 PRO A CB     1 ? 
ATOM   403  C CG     . PRO A 1 26  ? 11.531  -36.873 26.817  1    19.31  ? 1034 PRO A CG     1 ? 
ATOM   404  C CD     . PRO A 1 26  ? 11.963  -38.175 27.382  1    18.456 ? 1034 PRO A CD     1 ? 
ATOM   405  H HA     . PRO A 1 26  ? 14.393  -36.824 25.826  1    18.397 ? 1034 PRO A HA     1 c 
ATOM   406  H HB2    . PRO A 1 26  ? 12.732  -35.414 27.854  1    18.147 ? 1034 PRO A HB2    1 c 
ATOM   407  H HB3    . PRO A 1 26  ? 12.735  -35.239 26.089  1    18.144 ? 1034 PRO A HB3    1 c 
ATOM   408  H HG2    . PRO A 1 26  ? 10.694  -36.467 27.389  1    18.711 ? 1034 PRO A HG2    1 c 
ATOM   409  H HG3    . PRO A 1 26  ? 11.218  -36.993 25.778  1    18.75  ? 1034 PRO A HG3    1 c 
ATOM   410  H HD2    . PRO A 1 26  ? 11.831  -38.204 28.466  1    18.495 ? 1034 PRO A HD2    1 c 
ATOM   411  H HD3    . PRO A 1 26  ? 11.421  -39.003 26.928  1    18.641 ? 1034 PRO A HD3    1 c 
ATOM   412  N N      . PHE A 1 27  ? 15.706  -35.453 27.639  1    17.153 ? 1035 PHE A N      1 ? 
ATOM   413  C CA     . PHE A 1 27  ? 16.562  -34.888 28.665  1    16.931 ? 1035 PHE A CA     1 ? 
ATOM   414  C C      . PHE A 1 27  ? 15.754  -33.876 29.475  1    17.526 ? 1035 PHE A C      1 ? 
ATOM   415  O O      . PHE A 1 27  ? 15.115  -32.993 28.899  1    19.512 ? 1035 PHE A O      1 ? 
ATOM   416  C CB     . PHE A 1 27  ? 17.779  -34.19  28.05   1    16.787 ? 1035 PHE A CB     1 ? 
ATOM   417  C CG     . PHE A 1 27  ? 18.676  -33.6   29.098  1    16.072 ? 1035 PHE A CG     1 ? 
ATOM   418  C CD1    . PHE A 1 27  ? 19.523  -34.423 29.825  1    16.218 ? 1035 PHE A CD1    1 ? 
ATOM   419  C CD2    . PHE A 1 27  ? 18.601  -32.255 29.42   1    16.709 ? 1035 PHE A CD2    1 ? 
ATOM   420  C CE1    . PHE A 1 27  ? 20.319  -33.898 30.827  1    15.427 ? 1035 PHE A CE1    1 ? 
ATOM   421  C CE2    . PHE A 1 27  ? 19.383  -31.745 30.437  1    16.009 ? 1035 PHE A CE2    1 ? 
ATOM   422  C CZ     . PHE A 1 27  ? 20.244  -32.566 31.142  1    15.59  ? 1035 PHE A CZ     1 ? 
ATOM   423  H H      . PHE A 1 27  ? 15.521  -34.877 26.801  1    17.988 ? 1035 PHE A H      1 ? 
ATOM   424  H HA     . PHE A 1 27  ? 16.904  -35.686 29.326  1    17.065 ? 1035 PHE A HA     1 c 
ATOM   425  H HB2    . PHE A 1 27  ? 18.343  -34.917 27.462  1    16.659 ? 1035 PHE A HB2    1 c 
ATOM   426  H HB3    . PHE A 1 27  ? 17.433  -33.397 27.384  1    16.657 ? 1035 PHE A HB3    1 c 
ATOM   427  H HD1    . PHE A 1 27  ? 19.578  -35.481 29.59   1    16.013 ? 1035 PHE A HD1    1 c 
ATOM   428  H HD2    . PHE A 1 27  ? 17.916  -31.607 28.882  1    16.402 ? 1035 PHE A HD2    1 c 
ATOM   429  H HE1    . PHE A 1 27  ? 20.993  -34.547 31.376  1    15.646 ? 1035 PHE A HE1    1 c 
ATOM   430  H HE2    . PHE A 1 27  ? 19.336  -30.687 30.671  1    16.04  ? 1035 PHE A HE2    1 c 
ATOM   431  H HZ     . PHE A 1 27  ? 20.877  -32.153 31.92   1    15.659 ? 1035 PHE A HZ     1 c 
ATOM   432  N N      . THR A 1 28  ? 15.775  -33.994 30.801  1    16.08  ? 1036 THR A N      1 ? 
ATOM   433  C CA     . THR A 1 28  ? 15.057  -33.04  31.64   1    16.504 ? 1036 THR A CA     1 ? 
ATOM   434  C C      . THR A 1 28  ? 15.962  -31.848 31.906  1    14.98  ? 1036 THR A C      1 ? 
ATOM   435  O O      . THR A 1 28  ? 16.854  -31.906 32.754  1    13.935 ? 1036 THR A O      1 ? 
ATOM   436  C CB     . THR A 1 28  ? 14.559  -33.679 32.933  1    15.736 ? 1036 THR A CB     1 ? 
ATOM   437  O OG1    . THR A 1 28  ? 13.722  -34.797 32.613  1    14.625 ? 1036 THR A OG1    1 ? 
ATOM   438  C CG2    . THR A 1 28  ? 13.771  -32.663 33.757  1    16.67  ? 1036 THR A CG2    1 ? 
ATOM   439  H H      . THR A 1 28  ? 16.314  -34.762 31.236  1    15.927 ? 1036 THR A H      1 ? 
ATOM   440  H HA     . THR A 1 28  ? 14.186  -32.692 31.083  1    16.033 ? 1036 THR A HA     1 c 
ATOM   441  H HB     . THR A 1 28  ? 15.413  -34.025 33.519  1    15.809 ? 1036 THR A HB     1 c 
ATOM   442  H HG1    . THR A 1 28  ? 12.976  -34.536 32.073  1    15.495 ? 1036 THR A HG1    1 ? 
ATOM   443  H HG21   . THR A 1 28  ? 13.35   -33.155 34.635  1    16.404 ? 1036 THR A HG21   1 c 
ATOM   444  H HG22   . THR A 1 28  ? 14.433  -31.855 34.077  1    16.398 ? 1036 THR A HG22   1 c 
ATOM   445  H HG23   . THR A 1 28  ? 12.961  -32.251 33.15   1    16.407 ? 1036 THR A HG23   1 c 
ATOM   446  N N      . ALA A 1 29  ? 15.724  -30.773 31.161  1    15.073 ? 1037 ALA A N      1 ? 
ATOM   447  C CA     . ALA A 1 29  ? 16.46   -29.53  31.253  1    15.195 ? 1037 ALA A CA     1 ? 
ATOM   448  C C      . ALA A 1 29  ? 15.763  -28.582 32.225  1    16.118 ? 1037 ALA A C      1 ? 
ATOM   449  O O      . ALA A 1 29  ? 14.636  -28.814 32.651  1    16.317 ? 1037 ALA A O      1 ? 
ATOM   450  C CB     . ALA A 1 29  ? 16.59   -28.9   29.871  1    15.828 ? 1037 ALA A CB     1 ? 
ATOM   451  H H      . ALA A 1 29  ? 14.978  -30.846 30.446  1    14.747 ? 1037 ALA A H      1 ? 
ATOM   452  H HA     . ALA A 1 29  ? 17.457  -29.749 31.642  1    15.433 ? 1037 ALA A HA     1 c 
ATOM   453  H HB1    . ALA A 1 29  ? 17.148  -27.965 29.944  1    15.653 ? 1037 ALA A HB1    1 c 
ATOM   454  H HB2    . ALA A 1 29  ? 17.119  -29.584 29.204  1    15.647 ? 1037 ALA A HB2    1 c 
ATOM   455  H HB3    . ALA A 1 29  ? 15.597  -28.697 29.465  1    15.634 ? 1037 ALA A HB3    1 c 
ATOM   456  N N      . THR A 1 30  ? 16.458  -27.496 32.572  1    15.83  ? 1038 THR A N      1 ? 
ATOM   457  C CA     . THR A 1 30  ? 15.952  -26.545 33.55   1    15.239 ? 1038 THR A CA     1 ? 
ATOM   458  C C      . THR A 1 30  ? 15.949  -25.139 32.969  1    15.141 ? 1038 THR A C      1 ? 
ATOM   459  O O      . THR A 1 30  ? 16.954  -24.691 32.416  1    16.71  ? 1038 THR A O      1 ? 
ATOM   460  C CB     . THR A 1 30  ? 16.773  -26.588 34.848  1    16.076 ? 1038 THR A CB     1 ? 
ATOM   461  O OG1    . THR A 1 30  ? 16.756  -27.93  35.351  1    17.575 ? 1038 THR A OG1    1 ? 
ATOM   462  C CG2    . THR A 1 30  ? 16.201  -25.644 35.9    1    16.913 ? 1038 THR A CG2    1 ? 
ATOM   463  H H      . THR A 1 30  ? 17.434  -27.375 32.237  1    15.842 ? 1038 THR A H      1 ? 
ATOM   464  H HA     . THR A 1 30  ? 14.924  -26.819 33.79   1    15.479 ? 1038 THR A HA     1 c 
ATOM   465  H HB     . THR A 1 30  ? 17.804  -26.298 34.635  1    16.346 ? 1038 THR A HB     1 c 
ATOM   466  H HG1    . THR A 1 30  ? 17.386  -28.086 36.064  1    20.236 ? 1038 THR A HG1    1 ? 
ATOM   467  H HG21   . THR A 1 30  ? 16.753  -25.763 36.835  1    16.665 ? 1038 THR A HG21   1 c 
ATOM   468  H HG22   . THR A 1 30  ? 16.291  -24.612 35.556  1    16.658 ? 1038 THR A HG22   1 c 
ATOM   469  H HG23   . THR A 1 30  ? 15.148  -25.881 36.07   1    16.632 ? 1038 THR A HG23   1 c 
ATOM   470  N N      . ILE A 1 31  ? 14.828  -24.434 33.126  1    13.19  ? 1039 ILE A N      1 ? 
ATOM   471  C CA     . ILE A 1 31  ? 14.718  -23.059 32.667  1    13.843 ? 1039 ILE A CA     1 ? 
ATOM   472  C C      . ILE A 1 31  ? 15.621  -22.158 33.495  1    15.504 ? 1039 ILE A C      1 ? 
ATOM   473  O O      . ILE A 1 31  ? 15.583  -22.186 34.735  1    14.587 ? 1039 ILE A O      1 ? 
ATOM   474  C CB     . ILE A 1 31  ? 13.259  -22.591 32.758  1    14.8   ? 1039 ILE A CB     1 ? 
ATOM   475  C CG1    . ILE A 1 31  ? 12.372  -23.407 31.822  1    16.202 ? 1039 ILE A CG1    1 ? 
ATOM   476  C CG2    . ILE A 1 31  ? 13.153  -21.087 32.492  1    14.85  ? 1039 ILE A CG2    1 ? 
ATOM   477  C CD1    . ILE A 1 31  ? 12.433  -22.929 30.393  1    18.204 ? 1039 ILE A CD1    1 ? 
ATOM   478  H H      . ILE A 1 31  ? 14.017  -24.842 33.633  1    13.047 ? 1039 ILE A H      1 ? 
ATOM   479  H HA     . ILE A 1 31  ? 15.035  -23.014 31.623  1    14.17  ? 1039 ILE A HA     1 c 
ATOM   480  H HB     . ILE A 1 31  ? 12.917  -22.774 33.779  1    14.874 ? 1039 ILE A HB     1 c 
ATOM   481  H HG12   . ILE A 1 31  ? 12.682  -24.453 31.859  1    16.319 ? 1039 ILE A HG12   1 c 
ATOM   482  H HG13   . ILE A 1 31  ? 11.339  -23.348 32.171  1    16.304 ? 1039 ILE A HG13   1 c 
ATOM   483  H HG21   . ILE A 1 31  ? 13.687  -20.839 31.573  1    14.847 ? 1039 ILE A HG21   1 c 
ATOM   484  H HG22   . ILE A 1 31  ? 12.102  -20.808 32.387  1    14.835 ? 1039 ILE A HG22   1 c 
ATOM   485  H HG23   . ILE A 1 31  ? 13.592  -20.533 33.325  1    14.817 ? 1039 ILE A HG23   1 c 
ATOM   486  H HD11   . ILE A 1 31  ? 13.474  -22.906 30.062  1    17.595 ? 1039 ILE A HD11   1 c 
ATOM   487  H HD12   . ILE A 1 31  ? 11.866  -23.611 29.757  1    17.595 ? 1039 ILE A HD12   1 c 
ATOM   488  H HD13   . ILE A 1 31  ? 12.008  -21.926 30.317  1    17.522 ? 1039 ILE A HD13   1 c 
ATOM   489  N N      . VAL A 1 32  ? 16.403  -21.329 32.804  1    13.921 ? 1040 VAL A N      1 ? 
ATOM   490  C CA     . VAL A 1 32  ? 17.199  -20.285 33.435  1    15.039 ? 1040 VAL A CA     1 ? 
ATOM   491  C C      . VAL A 1 32  ? 16.427  -18.972 33.49   1    14.471 ? 1040 VAL A C      1 ? 
ATOM   492  O O      . VAL A 1 32  ? 16.369  -18.311 34.53   1    15.73  ? 1040 VAL A O      1 ? 
ATOM   493  C CB     . VAL A 1 32  ? 18.53   -20.108 32.677  1    14.427 ? 1040 VAL A CB     1 ? 
ATOM   494  C CG1    . VAL A 1 32  ? 19.328  -18.935 33.257  1    14.966 ? 1040 VAL A CG1    1 ? 
ATOM   495  C CG2    . VAL A 1 32  ? 19.333  -21.409 32.688  1    15.332 ? 1040 VAL A CG2    1 ? 
ATOM   496  H H      . VAL A 1 32  ? 16.394  -21.386 31.765  1    15.079 ? 1040 VAL A H      1 ? 
ATOM   497  H HA     . VAL A 1 32  ? 17.424  -20.596 34.457  1    14.613 ? 1040 VAL A HA     1 c 
ATOM   498  H HB     . VAL A 1 32  ? 18.284  -19.871 31.64   1    14.792 ? 1040 VAL A HB     1 c 
ATOM   499  H HG11   . VAL A 1 32  ? 18.802  -17.999 33.058  1    14.814 ? 1040 VAL A HG11   1 c 
ATOM   500  H HG12   . VAL A 1 32  ? 19.441  -19.066 34.335  1    14.816 ? 1040 VAL A HG12   1 c 
ATOM   501  H HG13   . VAL A 1 32  ? 20.314  -18.899 32.789  1    14.819 ? 1040 VAL A HG13   1 c 
ATOM   502  H HG21   . VAL A 1 32  ? 20.28   -21.257 32.166  1    15.074 ? 1040 VAL A HG21   1 c 
ATOM   503  H HG22   . VAL A 1 32  ? 19.532  -21.706 33.72   1    15.074 ? 1040 VAL A HG22   1 c 
ATOM   504  H HG23   . VAL A 1 32  ? 18.764  -22.194 32.187  1    15.068 ? 1040 VAL A HG23   1 c 
ATOM   505  N N      . SER A 1 33  ? 15.828  -18.573 32.366  1    15.766 ? 1041 SER A N      1 ? 
ATOM   506  C CA     . SER A 1 33  ? 15.15   -17.293 32.287  1    15.289 ? 1041 SER A CA     1 ? 
ATOM   507  C C      . SER A 1 33  ? 14.141  -17.316 31.145  1    16.979 ? 1041 SER A C      1 ? 
ATOM   508  O O      . SER A 1 33  ? 14.305  -18.055 30.176  1    15.955 ? 1041 SER A O      1 ? 
ATOM   509  C CB     . SER A 1 33  ? 16.114  -16.134 32.113  1    15.369 ? 1041 SER A CB     1 ? 
ATOM   510  O OG     . SER A 1 33  ? 16.859  -16.287 30.912  1    15     ? 1041 SER A OG     1 ? 
ATOM   511  H H      . SER A 1 33  ? 15.848  -19.177 31.527  1    14.821 ? 1041 SER A H      1 ? 
ATOM   512  H HA     . SER A 1 33  ? 14.6    -17.144 33.219  1    15.72  ? 1041 SER A HA     1 c 
ATOM   513  H HB2    . SER A 1 33  ? 15.555  -15.197 32.079  1    15.266 ? 1041 SER A HB2    1 c 
ATOM   514  H HB3    . SER A 1 33  ? 16.797  -16.098 32.964  1    15.266 ? 1041 SER A HB3    1 c 
ATOM   515  H HG     . SER A 1 33  ? 16.218  -16.198 30.188  1    15.465 ? 1041 SER A HG     1 ? 
ATOM   516  N N      . VAL A 1 34  ? 13.112  -16.482 31.267  1    15.906 ? 1042 VAL A N      1 ? 
ATOM   517  C CA     . VAL A 1 34  ? 12.129  -16.217 30.228  1    15.317 ? 1042 VAL A CA     1 ? 
ATOM   518  C C      . VAL A 1 34  ? 11.869  -14.716 30.244  1    16.285 ? 1042 VAL A C      1 ? 
ATOM   519  O O      . VAL A 1 34  ? 11.588  -14.149 31.303  1    17.805 ? 1042 VAL A O      1 ? 
ATOM   520  C CB     . VAL A 1 34  ? 10.796  -16.956 30.446  1    15.413 ? 1042 VAL A CB     1 ? 
ATOM   521  C CG1    . VAL A 1 34  ? 9.741   -16.524 29.405  1    16.575 ? 1042 VAL A CG1    1 ? 
ATOM   522  C CG2    . VAL A 1 34  ? 11.005  -18.46  30.415  1    16.056 ? 1042 VAL A CG2    1 ? 
ATOM   523  H H      . VAL A 1 34  ? 13.034  -15.924 32.14   1    16.629 ? 1042 VAL A H      1 ? 
ATOM   524  H HA     . VAL A 1 34  ? 12.545  -16.501 29.261  1    15.601 ? 1042 VAL A HA     1 c 
ATOM   525  H HB     . VAL A 1 34  ? 10.43   -16.683 31.438  1    15.711 ? 1042 VAL A HB     1 c 
ATOM   526  H HG11   . VAL A 1 34  ? 10.153  -16.641 28.4    1    16.24  ? 1042 VAL A HG11   1 c 
ATOM   527  H HG12   . VAL A 1 34  ? 8.851   -17.147 29.507  1    16.241 ? 1042 VAL A HG12   1 c 
ATOM   528  H HG13   . VAL A 1 34  ? 9.472   -15.478 29.566  1    16.223 ? 1042 VAL A HG13   1 c 
ATOM   529  H HG21   . VAL A 1 34  ? 11.394  -18.752 29.438  1    15.929 ? 1042 VAL A HG21   1 c 
ATOM   530  H HG22   . VAL A 1 34  ? 11.717  -18.747 31.191  1    15.891 ? 1042 VAL A HG22   1 c 
ATOM   531  H HG23   . VAL A 1 34  ? 10.053  -18.965 30.591  1    15.882 ? 1042 VAL A HG23   1 c 
ATOM   532  N N      . GLU A 1 35  ? 11.979  -14.063 29.085  1    16.179 ? 1043 GLU A N      1 ? 
ATOM   533  C CA     . GLU A 1 35  ? 11.771  -12.626 28.98   1    17.319 ? 1043 GLU A CA     1 ? 
ATOM   534  C C      . GLU A 1 35  ? 11.02   -12.334 27.683  1    18.962 ? 1043 GLU A C      1 ? 
ATOM   535  O O      . GLU A 1 35  ? 11.274  -12.965 26.657  1    18.562 ? 1043 GLU A O      1 ? 
ATOM   536  C CB     . GLU A 1 35  ? 13.067  -11.809 29.062  1    18.694 ? 1043 GLU A CB     1 ? 
ATOM   537  C CG     . GLU A 1 35  ? 13.915  -11.819 27.78   0.4  21.014 ? 1043 GLU A CG     1 ? 
ATOM   538  C CD     . GLU A 1 35  ? 15.355  -11.289 27.805  0.33 22.497 ? 1043 GLU A CD     1 ? 
ATOM   539  O OE1    . GLU A 1 35  ? 16.153  -11.658 28.692  0.8  25.021 ? 1043 GLU A OE1    1 ? 
ATOM   540  O OE2    . GLU A 1 35  ? 15.733  -10.554 26.866  0.73 22.79  ? 1043 GLU A OE2    1 ? 
ATOM   541  H H      . GLU A 1 35  ? 12.246  -14.588 28.23   1    16.216 ? 1043 GLU A H      1 ? 
ATOM   542  H HA     . GLU A 1 35  ? 11.134  -12.318 29.811  0.95 17.615 ? 1043 GLU A HA     1 c 
ATOM   543  H HB2    . GLU A 1 35  ? 12.812  -10.775 29.302  0.96 18.859 ? 1043 GLU A HB2    1 c 
ATOM   544  H HB3    . GLU A 1 35  ? 13.673  -12.199 29.882  0.28 18.859 ? 1043 GLU A HB3    1 c 
ATOM   545  H HG2    . GLU A 1 35  ? 13.954  -12.847 27.418  0.58 20.756 ? 1043 GLU A HG2    1 c 
ATOM   546  H HG3    . GLU A 1 35  ? 13.375  -11.253 27.018  0.36 20.829 ? 1043 GLU A HG3    1 c 
ATOM   547  N N      . SER A 1 36  ? 10.116  -11.35  27.726  1    18.883 ? 1044 SER A N      1 ? 
ATOM   548  C CA     . SER A 1 36  ? 9.5     -10.889 26.498  1    18.609 ? 1044 SER A CA     1 ? 
ATOM   549  C C      . SER A 1 36  ? 10.527  -10.123 25.669  1    16.8   ? 1044 SER A C      1 ? 
ATOM   550  O O      . SER A 1 36  ? 11.33   -9.359  26.21   1    17.347 ? 1044 SER A O      1 ? 
ATOM   551  C CB     . SER A 1 36  ? 8.321   -9.982  26.799  1    19.837 ? 1044 SER A CB     1 ? 
ATOM   552  O OG     . SER A 1 36  ? 7.838   -9.42   25.58   1    16.662 ? 1044 SER A OG     1 ? 
ATOM   553  H H      . SER A 1 36  ? 9.94    -10.824 28.599  1    17.549 ? 1044 SER A H      1 ? 
ATOM   554  H HA     . SER A 1 36  ? 9.153   -11.753 25.927  1    18.535 ? 1044 SER A HA     1 c 
ATOM   555  H HB2    . SER A 1 36  ? 7.528   -10.558 27.28   1    18.794 ? 1044 SER A HB2    1 c 
ATOM   556  H HB3    . SER A 1 36  ? 8.635   -9.184  27.475  1    18.794 ? 1044 SER A HB3    1 c 
ATOM   557  N N      . LEU A 1 37  ? 10.504  -10.339 24.353  1    17.204 ? 1045 LEU A N      1 ? 
ATOM   558  C CA     . LEU A 1 37  ? 11.37   -9.634  23.423  1    17.232 ? 1045 LEU A CA     1 ? 
ATOM   559  C C      . LEU A 1 37  ? 10.71   -8.41   22.8    1    18.284 ? 1045 LEU A C      1 ? 
ATOM   560  O O      . LEU A 1 37  ? 11.34   -7.732  21.985  1    19.84  ? 1045 LEU A O      1 ? 
ATOM   561  C CB     . LEU A 1 37  ? 11.807  -10.583 22.306  1    16.238 ? 1045 LEU A CB     1 ? 
ATOM   562  C CG     . LEU A 1 37  ? 12.797  -11.658 22.749  1    15.531 ? 1045 LEU A CG     1 ? 
ATOM   563  C CD1    . LEU A 1 37  ? 12.901  -12.723 21.671  1    15.636 ? 1045 LEU A CD1    1 ? 
ATOM   564  C CD2    . LEU A 1 37  ? 14.165  -11.045 23.027  1    14.378 ? 1045 LEU A CD2    1 ? 
ATOM   565  H H      . LEU A 1 37  ? 9.801   -10.978 23.947  1    17.965 ? 1045 LEU A H      1 ? 
ATOM   566  H HA     . LEU A 1 37  ? 12.254  -9.302  23.97   1    17.192 ? 1045 LEU A HA     1 c 
ATOM   567  H HB2    . LEU A 1 37  ? 10.919  -11.073 21.902  1    16.295 ? 1045 LEU A HB2    1 c 
ATOM   568  H HB3    . LEU A 1 37  ? 12.268  -9.993  21.511  1    16.31  ? 1045 LEU A HB3    1 c 
ATOM   569  H HG     . LEU A 1 37  ? 12.424  -12.12  23.666  1    15.459 ? 1045 LEU A HG     1 c 
ATOM   570  H HD11   . LEU A 1 37  ? 13.608  -13.493 21.985  1    15.611 ? 1045 LEU A HD11   1 c 
ATOM   571  H HD12   . LEU A 1 37  ? 11.92   -13.175 21.508  1    15.611 ? 1045 LEU A HD12   1 c 
ATOM   572  H HD13   . LEU A 1 37  ? 13.25   -12.268 20.741  1    15.624 ? 1045 LEU A HD13   1 c 
ATOM   573  H HD21   . LEU A 1 37  ? 14.513  -10.511 22.14   1    14.704 ? 1045 LEU A HD21   1 c 
ATOM   574  H HD22   . LEU A 1 37  ? 14.089  -10.347 23.863  1    14.72  ? 1045 LEU A HD22   1 c 
ATOM   575  H HD23   . LEU A 1 37  ? 14.876  -11.834 23.278  1    14.735 ? 1045 LEU A HD23   1 c 
ATOM   576  N N      . VAL A 1 38  ? 9.444   -8.133  23.133  1    18.966 ? 1046 VAL A N      1 ? 
ATOM   577  C CA     . VAL A 1 38  ? 8.65    -7.192  22.356  1    20.074 ? 1046 VAL A CA     1 ? 
ATOM   578  C C      . VAL A 1 38  ? 8.042   -6.127  23.26   1    22.949 ? 1046 VAL A C      1 ? 
ATOM   579  O O      . VAL A 1 38  ? 7.91    -6.295  24.476  1    22.193 ? 1046 VAL A O      1 ? 
ATOM   580  C CB     . VAL A 1 38  ? 7.566   -7.894  21.511  1    20.773 ? 1046 VAL A CB     1 ? 
ATOM   581  C CG1    . VAL A 1 38  ? 8.208   -8.84   20.494  1    21.268 ? 1046 VAL A CG1    1 ? 
ATOM   582  C CG2    . VAL A 1 38  ? 6.541   -8.603  22.383  1    21.083 ? 1046 VAL A CG2    1 ? 
ATOM   583  H H      . VAL A 1 38  ? 8.978   -8.74   23.824  1    17.174 ? 1046 VAL A H      1 ? 
ATOM   584  H HA     . VAL A 1 38  ? 9.324   -6.687  21.665  1    20.522 ? 1046 VAL A HA     1 c 
ATOM   585  H HB     . VAL A 1 38  ? 7.042   -7.117  20.954  1    20.871 ? 1046 VAL A HB     1 c 
ATOM   586  H HG11   . VAL A 1 38  ? 8.793   -9.598  21.019  1    21.122 ? 1046 VAL A HG11   1 c 
ATOM   587  H HG12   . VAL A 1 38  ? 7.427   -9.327  19.906  1    21.122 ? 1046 VAL A HG12   1 c 
ATOM   588  H HG13   . VAL A 1 38  ? 8.862   -8.272  19.83   1    21.1   ? 1046 VAL A HG13   1 c 
ATOM   589  H HG21   . VAL A 1 38  ? 6.009   -7.87   22.994  1    20.992 ? 1046 VAL A HG21   1 c 
ATOM   590  H HG22   . VAL A 1 38  ? 5.827   -9.132  21.749  1    20.984 ? 1046 VAL A HG22   1 c 
ATOM   591  H HG23   . VAL A 1 38  ? 7.047   -9.319  23.033  1    20.938 ? 1046 VAL A HG23   1 c 
ATOM   592  N N      . GLY A 1 39  ? 7.656   -5.023  22.624  1    24.65  ? 1047 GLY A N      1 ? 
ATOM   593  C CA     . GLY A 1 39  ? 7.074   -3.895  23.31   1    24.557 ? 1047 GLY A CA     1 ? 
ATOM   594  C C      . GLY A 1 39  ? 5.555   -3.922  23.255  1    25.67  ? 1047 GLY A C      1 ? 
ATOM   595  O O      . GLY A 1 39  ? 4.937   -4.814  22.67   1    26.492 ? 1047 GLY A O      1 ? 
ATOM   596  H H      . GLY A 1 39  ? 7.829   -4.934  21.605  1    22.961 ? 1047 GLY A H      1 ? 
ATOM   597  H HA2    . GLY A 1 39  ? 7.402   -3.902  24.351  1    24.802 ? 1047 GLY A HA2    1 c 
ATOM   598  H HA3    . GLY A 1 39  ? 7.438   -2.974  22.85   1    24.844 ? 1047 GLY A HA3    1 c 
ATOM   599  N N      . PRO A 1 40  ? 4.921   -2.916  23.88   1    27.992 ? 1048 PRO A N      1 ? 
ATOM   600  C CA     . PRO A 1 40  ? 3.473   -2.976  24.07   1    28.953 ? 1048 PRO A CA     1 ? 
ATOM   601  C C      . PRO A 1 40  ? 2.647   -2.911  22.787  1    28.252 ? 1048 PRO A C      1 ? 
ATOM   602  O O      . PRO A 1 40  ? 1.495   -3.359  22.794  1    33.558 ? 1048 PRO A O      1 ? 
ATOM   603  C CB     . PRO A 1 40  ? 3.181   -1.803  25.011  1    29.233 ? 1048 PRO A CB     1 ? 
ATOM   604  C CG     . PRO A 1 40  ? 4.332   -0.866  24.811  1    30.811 ? 1048 PRO A CG     1 ? 
ATOM   605  C CD     . PRO A 1 40  ? 5.528   -1.744  24.526  1    28.778 ? 1048 PRO A CD     1 ? 
ATOM   606  H HA     . PRO A 1 40  ? 3.23    -3.903  24.593  1    28.694 ? 1048 PRO A HA     1 c 
ATOM   607  H HB2    . PRO A 1 40  ? 2.237   -1.321  24.749  1    29.511 ? 1048 PRO A HB2    1 c 
ATOM   608  H HB3    . PRO A 1 40  ? 3.129   -2.14   26.048  1    29.511 ? 1048 PRO A HB3    1 c 
ATOM   609  H HG2    . PRO A 1 40  ? 4.143   -0.194  23.971  1    30.012 ? 1048 PRO A HG2    1 c 
ATOM   610  H HG3    . PRO A 1 40  ? 4.504   -0.266  25.708  1    30.012 ? 1048 PRO A HG3    1 c 
ATOM   611  H HD2    . PRO A 1 40  ? 6.234   -1.252  23.855  1    29.022 ? 1048 PRO A HD2    1 c 
ATOM   612  H HD3    . PRO A 1 40  ? 6.041   -2.031  25.446  1    29.022 ? 1048 PRO A HD3    1 c 
ATOM   613  N N      . LYS A 1 41  ? 3.193   -2.38   21.691  1    26.443 ? 1049 LYS A N      1 ? 
ATOM   614  C CA     . LYS A 1 41  ? 2.449   -2.306  20.443  1    25.134 ? 1049 LYS A CA     1 ? 
ATOM   615  C C      . LYS A 1 41  ? 2.575   -3.569  19.593  1    27.352 ? 1049 LYS A C      1 ? 
ATOM   616  O O      . LYS A 1 41  ? 1.938   -3.651  18.538  1    23.669 ? 1049 LYS A O      1 ? 
ATOM   617  C CB     . LYS A 1 41  ? 2.826   -1.132  19.527  1    29.255 ? 1049 LYS A CB     1 ? 
ATOM   618  C CG     . LYS A 1 41  ? 2.603   0.257   20.11   1    35.161 ? 1049 LYS A CG     1 ? 
ATOM   619  C CD     . LYS A 1 41  ? 2.955   1.369   19.127  1    39.129 ? 1049 LYS A CD     1 ? 
ATOM   620  C CE     . LYS A 1 41  ? 3.318   2.659   19.823  1    45.409 ? 1049 LYS A CE     1 ? 
ATOM   621  N NZ     . LYS A 1 41  ? 3.896   3.621   18.875  1    49.795 ? 1049 LYS A NZ     1 ? 
ATOM   622  H H      . LYS A 1 41  ? 4.121   -1.91   21.743  1    23.946 ? 1049 LYS A H      1 ? 
ATOM   623  H HA     . LYS A 1 41  ? 1.394   -2.181  20.696  1    26.51  ? 1049 LYS A HA     1 c 
ATOM   624  H HB2    . LYS A 1 41  ? 3.881   -1.226  19.261  1    29.468 ? 1049 LYS A HB2    1 c 
ATOM   625  H HB3    . LYS A 1 41  ? 2.247   -1.211  18.604  1    29.437 ? 1049 LYS A HB3    1 c 
ATOM   626  H HG2    . LYS A 1 41  ? 1.555   0.352   20.4    1    34.563 ? 1049 LYS A HG2    1 c 
ATOM   627  H HG3    . LYS A 1 41  ? 3.215   0.363   21.008  1    34.563 ? 1049 LYS A HG3    1 c 
ATOM   628  H HD2    . LYS A 1 41  ? 3.797   1.047   18.511  1    39.505 ? 1049 LYS A HD2    1 c 
ATOM   629  H HD3    . LYS A 1 41  ? 2.102   1.547   18.469  1    39.505 ? 1049 LYS A HD3    1 c 
ATOM   630  H HE2    . LYS A 1 41  ? 2.425   3.096   20.274  1    44.901 ? 1049 LYS A HE2    1 c 
ATOM   631  H HE3    . LYS A 1 41  ? 4.039   2.46    20.616  1    44.958 ? 1049 LYS A HE3    1 c 
ATOM   632  H HZ1    . LYS A 1 41  ? 3.915   4.548   19.3    0.5  47.53  ? 1049 LYS A HZ1    1 ? 
ATOM   633  H HZ2    . LYS A 1 41  ? 4.847   3.351   18.625  1    45.382 ? 1049 LYS A HZ2    1 ? 
ATOM   634  H HZ3    . LYS A 1 41  ? 3.323   3.654   18.027  1    47.168 ? 1049 LYS A HZ3    1 ? 
ATOM   635  N N      . ALA A 1 42  ? 3.372   -4.55   20.019  1    25.209 ? 1050 ALA A N      1 ? 
ATOM   636  C CA     . ALA A 1 42  ? 3.472   -5.782  19.258  1    26.629 ? 1050 ALA A CA     1 ? 
ATOM   637  C C      . ALA A 1 42  ? 2.131   -6.509  19.263  1    27.635 ? 1050 ALA A C      1 ? 
ATOM   638  O O      . ALA A 1 42  ? 1.448   -6.556  20.287  1    30.578 ? 1050 ALA A O      1 ? 
ATOM   639  C CB     . ALA A 1 42  ? 4.544   -6.69   19.851  1    26.627 ? 1050 ALA A CB     1 ? 
ATOM   640  H H      . ALA A 1 42  ? 3.875   -4.463  20.912  1    24.418 ? 1050 ALA A H      1 ? 
ATOM   641  H HA     . ALA A 1 42  ? 3.735   -5.532  18.23   1    26.59  ? 1050 ALA A HA     1 c 
ATOM   642  H HB1    . ALA A 1 42  ? 5.511   -6.185  19.819  1    26.564 ? 1050 ALA A HB1    1 c 
ATOM   643  H HB2    . ALA A 1 42  ? 4.294   -6.926  20.888  1    26.607 ? 1050 ALA A HB2    1 c 
ATOM   644  H HB3    . ALA A 1 42  ? 4.602   -7.616  19.274  1    26.587 ? 1050 ALA A HB3    1 c 
ATOM   645  N N      . PRO A 1 43  ? 1.713   -7.085  18.125  1    29.086 ? 1051 PRO A N      1 ? 
ATOM   646  C CA     . PRO A 1 43  ? 0.416   -7.768  18.075  1    32.033 ? 1051 PRO A CA     1 ? 
ATOM   647  C C      . PRO A 1 43  ? 0.314   -8.984  18.988  1    32.827 ? 1051 PRO A C      1 ? 
ATOM   648  O O      . PRO A 1 43  ? -0.795  -9.372  19.361  1    37.031 ? 1051 PRO A O      1 ? 
ATOM   649  C CB     . PRO A 1 43  ? 0.259   -8.21   16.63   1    30.413 ? 1051 PRO A CB     1 ? 
ATOM   650  C CG     . PRO A 1 43  ? 1.282   -7.387  15.86   1    31.929 ? 1051 PRO A CG     1 ? 
ATOM   651  C CD     . PRO A 1 43  ? 2.38    -7.068  16.811  1    31.277 ? 1051 PRO A CD     1 ? 
ATOM   652  H HA     . PRO A 1 43  ? -0.375  -7.059  18.327  1    31.311 ? 1051 PRO A HA     1 c 
ATOM   653  H HB2    . PRO A 1 43  ? 0.462   -9.278  16.526  1    31.09  ? 1051 PRO A HB2    1 c 
ATOM   654  H HB3    . PRO A 1 43  ? -0.753  -8.008  16.271  1    31.082 ? 1051 PRO A HB3    1 c 
ATOM   655  H HG2    . PRO A 1 43  ? 1.669   -7.953  15.011  1    31.447 ? 1051 PRO A HG2    1 c 
ATOM   656  H HG3    . PRO A 1 43  ? 0.829   -6.467  15.485  1    31.421 ? 1051 PRO A HG3    1 c 
ATOM   657  H HD2    . PRO A 1 43  ? 3.17    -7.82   16.769  1    30.826 ? 1051 PRO A HD2    1 c 
ATOM   658  H HD3    . PRO A 1 43  ? 2.806   -6.084  16.604  1    30.835 ? 1051 PRO A HD3    1 c 
ATOM   659  N N      . GLY A 1 44  ? 1.436   -9.6    19.342  1    30.083 ? 1052 GLY A N      1 ? 
ATOM   660  C CA     . GLY A 1 44  ? 1.43    -10.71  20.278  1    26.413 ? 1052 GLY A CA     1 ? 
ATOM   661  C C      . GLY A 1 44  ? 2.807   -10.812 20.885  1    24.951 ? 1052 GLY A C      1 ? 
ATOM   662  O O      . GLY A 1 44  ? 3.728   -10.099 20.497  1    23.225 ? 1052 GLY A O      1 ? 
ATOM   663  H H      . GLY A 1 44  ? 2.322   -9.352  18.874  1    31.685 ? 1052 GLY A H      1 ? 
ATOM   664  H HA2    . GLY A 1 44  ? 0.687   -10.533 21.058  1    26.908 ? 1052 GLY A HA2    1 c 
ATOM   665  H HA3    . GLY A 1 44  ? 1.176   -11.635 19.757  1    26.799 ? 1052 GLY A HA3    1 c 
ATOM   666  N N      . GLU A 1 45  ? 2.943   -11.703 21.868  1    24.003 ? 1053 GLU A N      1 ? 
ATOM   667  C CA     . GLU A 1 45  ? 4.19    -11.829 22.596  1    21.305 ? 1053 GLU A CA     1 ? 
ATOM   668  C C      . GLU A 1 45  ? 5.108   -12.85  21.917  1    18.152 ? 1053 GLU A C      1 ? 
ATOM   669  O O      . GLU A 1 45  ? 4.67    -13.906 21.449  1    17.097 ? 1053 GLU A O      1 ? 
ATOM   670  C CB     . GLU A 1 45  ? 3.91    -12.232 24.046  1    23.267 ? 1053 GLU A CB     1 ? 
ATOM   671  C CG     . GLU A 1 45  ? 5.169   -12.2   24.937  1    26.053 ? 1053 GLU A CG     1 ? 
ATOM   672  C CD     . GLU A 1 45  ? 5.066   -12.791 26.35   1    32.002 ? 1053 GLU A CD     1 ? 
ATOM   673  O OE1    . GLU A 1 45  ? 3.938   -12.985 26.87   1    35.915 ? 1053 GLU A OE1    1 ? 
ATOM   674  O OE2    . GLU A 1 45  ? 6.128   -13.094 26.951  1    33.307 ? 1053 GLU A OE2    1 ? 
ATOM   675  H H      . GLU A 1 45  ? 2.147   -12.28  22.182  1    20.27  ? 1053 GLU A H      1 ? 
ATOM   676  H HA     . GLU A 1 45  ? 4.688   -10.857 22.596  1    21.478 ? 1053 GLU A HA     1 c 
ATOM   677  H HB2    . GLU A 1 45  ? 3.161   -11.555 24.462  1    23.387 ? 1053 GLU A HB2    1 c 
ATOM   678  H HB3    . GLU A 1 45  ? 3.491   -13.24  24.057  1    23.387 ? 1053 GLU A HB3    1 c 
ATOM   679  H HG2    . GLU A 1 45  ? 5.972   -12.726 24.417  1    26.473 ? 1053 GLU A HG2    1 c 
ATOM   680  H HG3    . GLU A 1 45  ? 5.492   -11.161 25.034  1    26.573 ? 1053 GLU A HG3    1 c 
ATOM   681  N N      . THR A 1 46  ? 6.393   -12.494 21.854  1    16.652 ? 1054 THR A N      1 ? 
ATOM   682  C CA     . THR A 1 46  ? 7.448   -13.422 21.505  1    17.171 ? 1054 THR A CA     1 ? 
ATOM   683  C C      . THR A 1 46  ? 8.445   -13.336 22.657  1    16.797 ? 1054 THR A C      1 ? 
ATOM   684  O O      . THR A 1 46  ? 8.799   -12.231 23.076  1    15.229 ? 1054 THR A O      1 ? 
ATOM   685  C CB     . THR A 1 46  ? 8.122   -13.031 20.187  1    17.996 ? 1054 THR A CB     1 ? 
ATOM   686  O OG1    . THR A 1 46  ? 7.16    -13.106 19.138  1    17.742 ? 1054 THR A OG1    1 ? 
ATOM   687  C CG2    . THR A 1 46  ? 9.254   -13.991 19.834  1    18.447 ? 1054 THR A CG2    1 ? 
ATOM   688  H H      . THR A 1 46  ? 6.689   -11.588 22.234  1    16.392 ? 1054 THR A H      1 ? 
ATOM   689  H HA     . THR A 1 46  ? 7.043   -14.431 21.432  1    17.153 ? 1054 THR A HA     1 c 
ATOM   690  H HB     . THR A 1 46  ? 8.511   -12.013 20.254  1    17.879 ? 1054 THR A HB     1 c 
ATOM   691  H HG1    . THR A 1 46  ? 6.742   -12.24  19.079  1    19.74  ? 1054 THR A HG1    1 ? 
ATOM   692  H HG21   . THR A 1 46  ? 8.865   -15.01  19.781  1    18.309 ? 1054 THR A HG21   1 c 
ATOM   693  H HG22   . THR A 1 46  ? 9.678   -13.715 18.866  1    18.311 ? 1054 THR A HG22   1 c 
ATOM   694  H HG23   . THR A 1 46  ? 10.031  -13.939 20.599  1    18.28  ? 1054 THR A HG23   1 c 
ATOM   695  N N      A CYS A 1 47  ? 8.907   -14.511 23.104  0.52 17.98  ? 1055 CYS A N      1 ? 
ATOM   696  N N      B CYS A 1 47  ? 8.874   -14.483 23.189  0.48 17.274 ? 1055 CYS A N      1 ? 
ATOM   697  C CA     A CYS A 1 47  ? 9.72    -14.629 24.305  0.52 17.623 ? 1055 CYS A CA     1 ? 
ATOM   698  C CA     B CYS A 1 47  ? 9.763   -14.449 24.341  0.48 16.427 ? 1055 CYS A CA     1 ? 
ATOM   699  C C      A CYS A 1 47  ? 11.108  -15.183 23.961  0.52 16.818 ? 1055 CYS A C      1 ? 
ATOM   700  C C      B CYS A 1 47  ? 11.06   -15.203 24.034  0.48 16.125 ? 1055 CYS A C      1 ? 
ATOM   701  O O      A CYS A 1 47  ? 11.28   -15.832 22.929  0.52 15.673 ? 1055 CYS A O      1 ? 
ATOM   702  O O      B CYS A 1 47  ? 11.115  -16.014 23.113  0.48 15.044 ? 1055 CYS A O      1 ? 
ATOM   703  C CB     A CYS A 1 47  ? 9.038   -15.548 25.308  0.52 18.189 ? 1055 CYS A CB     1 ? 
ATOM   704  C CB     B CYS A 1 47  ? 9.069   -14.994 25.581  0.48 16.119 ? 1055 CYS A CB     1 ? 
ATOM   705  S SG     A CYS A 1 47  ? 7.243   -15.309 25.411  0.52 18.364 ? 1055 CYS A SG     1 ? 
ATOM   706  S SG     B CYS A 1 47  ? 9.046   -16.805 25.623  0.48 15.765 ? 1055 CYS A SG     1 ? 
ATOM   707  H H      A CYS A 1 47  ? 8.696   -15.376 22.573  0.52 17.79  ? 1055 CYS A H      1 ? 
ATOM   708  H H      B CYS A 1 47  ? 8.605   -15.398 22.783  0.48 16.979 ? 1055 CYS A H      1 ? 
ATOM   709  H HA     A CYS A 1 47  ? 9.837   -13.636 24.741  0.52 17.627 ? 1055 CYS A HA     1 c 
ATOM   710  H HA     B CYS A 1 47  ? 10.018  -13.406 24.537  0.48 16.477 ? 1055 CYS A HA     1 c 
ATOM   711  H HB2    A CYS A 1 47  ? 9.234   -16.586 25.032  0.52 18.09  ? 1055 CYS A HB2    1 c 
ATOM   712  H HB2    B CYS A 1 47  ? 9.58    -14.631 26.474  0.48 16.141 ? 1055 CYS A HB2    1 c 
ATOM   713  H HB3    A CYS A 1 47  ? 9.467   -15.378 26.298  0.52 18.09  ? 1055 CYS A HB3    1 c 
ATOM   714  H HB3    B CYS A 1 47  ? 8.039   -14.631 25.608  0.48 16.135 ? 1055 CYS A HB3    1 c 
ATOM   715  N N      . HIS A 1 48  ? 12.099  -14.863 24.809  1    16.253 ? 1056 HIS A N      1 ? 
ATOM   716  C CA     . HIS A 1 48  ? 13.416  -15.47  24.75   1    16.255 ? 1056 HIS A CA     1 ? 
ATOM   717  C C      . HIS A 1 48  ? 13.541  -16.374 25.974  1    15.896 ? 1056 HIS A C      1 ? 
ATOM   718  O O      . HIS A 1 48  ? 13.377  -15.918 27.112  1    13.837 ? 1056 HIS A O      1 ? 
ATOM   719  C CB     . HIS A 1 48  ? 14.485  -14.382 24.802  1    15.908 ? 1056 HIS A CB     1 ? 
ATOM   720  C CG     . HIS A 1 48  ? 15.871  -14.874 24.507  1    18.198 ? 1056 HIS A CG     1 ? 
ATOM   721  N ND1    . HIS A 1 48  ? 16.298  -15.165 23.23   1    17.738 ? 1056 HIS A ND1    1 ? 
ATOM   722  C CD2    . HIS A 1 48  ? 16.933  -15.066 25.321  1    17.836 ? 1056 HIS A CD2    1 ? 
ATOM   723  C CE1    . HIS A 1 48  ? 17.563  -15.542 23.281  1    18.837 ? 1056 HIS A CE1    1 ? 
ATOM   724  N NE2    . HIS A 1 48  ? 17.969  -15.487 24.537  1    17.567 ? 1056 HIS A NE2    1 ? 
ATOM   725  H H      . HIS A 1 48  ? 11.93   -14.163 25.55   1    14.675 ? 1056 HIS A H      1 ? 
ATOM   726  H HA     . HIS A 1 48  ? 13.518  -16.071 23.847  1    16.117 ? 1056 HIS A HA     1 c 
ATOM   727  H HB2    . HIS A 1 48  ? 14.225  -13.606 24.081  1    16.442 ? 1056 HIS A HB2    1 c 
ATOM   728  H HB3    . HIS A 1 48  ? 14.475  -13.931 25.795  1    16.496 ? 1056 HIS A HB3    1 c 
ATOM   729  H HD2    . HIS A 1 48  ? 16.964  -14.924 26.397  1    17.855 ? 1056 HIS A HD2    1 c 
ATOM   730  H HE1    . HIS A 1 48  ? 18.165  -15.846 22.431  1    18.305 ? 1056 HIS A HE1    1 c 
ATOM   731  H HE2    . HIS A 1 48  ? 18.892  -15.734 24.795  1    18.736 ? 1056 HIS A HE2    1 ? 
ATOM   732  N N      . ILE A 1 49  ? 13.78   -17.663 25.729  1    17.836 ? 1057 ILE A N      1 ? 
ATOM   733  C CA     . ILE A 1 49  ? 13.863  -18.694 26.759  1    18.793 ? 1057 ILE A CA     1 ? 
ATOM   734  C C      . ILE A 1 49  ? 15.278  -19.231 26.81   1    15.581 ? 1057 ILE A C      1 ? 
ATOM   735  O O      . ILE A 1 49  ? 15.773  -19.742 25.805  1    16.781 ? 1057 ILE A O      1 ? 
ATOM   736  C CB     . ILE A 1 49  ? 12.907  -19.859 26.468  1    21.38  ? 1057 ILE A CB     1 ? 
ATOM   737  C CG1    . ILE A 1 49  ? 11.52   -19.293 26.244  1    24.82  ? 1057 ILE A CG1    1 ? 
ATOM   738  C CG2    . ILE A 1 49  ? 12.78   -20.774 27.676  1    22.978 ? 1057 ILE A CG2    1 ? 
ATOM   739  C CD1    . ILE A 1 49  ? 10.892  -19.589 24.888  1    29.43  ? 1057 ILE A CD1    1 ? 
ATOM   740  H H      . ILE A 1 49  ? 13.923  -17.955 24.744  1    17.195 ? 1057 ILE A H      1 ? 
ATOM   741  H HA     . ILE A 1 49  ? 13.609  -18.257 27.726  1    18.363 ? 1057 ILE A HA     1 c 
ATOM   742  H HB     . ILE A 1 49  ? 13.237  -20.419 25.591  1    21.742 ? 1057 ILE A HB     1 c 
ATOM   743  H HG12   . ILE A 1 49  ? 10.859  -19.688 27.018  1    24.875 ? 1057 ILE A HG12   1 c 
ATOM   744  H HG13   . ILE A 1 49  ? 11.56   -18.21  26.375  1    24.72  ? 1057 ILE A HG13   1 c 
ATOM   745  H HG21   . ILE A 1 49  ? 12.462  -20.194 28.544  1    22.408 ? 1057 ILE A HG21   1 c 
ATOM   746  H HG22   . ILE A 1 49  ? 12.04   -21.551 27.47   1    22.466 ? 1057 ILE A HG22   1 c 
ATOM   747  H HG23   . ILE A 1 49  ? 13.744  -21.24  27.887  1    22.351 ? 1057 ILE A HG23   1 c 
ATOM   748  H HD11   . ILE A 1 49  ? 9.831   -19.333 24.9    1    27.851 ? 1057 ILE A HD11   1 c 
ATOM   749  H HD12   . ILE A 1 49  ? 11.398  -19.005 24.116  1    27.788 ? 1057 ILE A HD12   1 c 
ATOM   750  H HD13   . ILE A 1 49  ? 11.003  -20.653 24.672  1    27.628 ? 1057 ILE A HD13   1 c 
ATOM   751  N N      . VAL A 1 50  ? 15.906  -19.177 27.987  1    18.547 ? 1058 VAL A N      1 ? 
ATOM   752  C CA     . VAL A 1 50  ? 17.235  -19.744 28.191  1    18.646 ? 1058 VAL A CA     1 ? 
ATOM   753  C C      . VAL A 1 50  ? 17.076  -21.044 28.976  1    15.452 ? 1058 VAL A C      1 ? 
ATOM   754  O O      . VAL A 1 50  ? 16.441  -21.056 30.038  1    16.802 ? 1058 VAL A O      1 ? 
ATOM   755  C CB     . VAL A 1 50  ? 18.176  -18.766 28.91   1    16.716 ? 1058 VAL A CB     1 ? 
ATOM   756  C CG1    . VAL A 1 50  ? 19.552  -19.388 29.109  1    18.345 ? 1058 VAL A CG1    1 ? 
ATOM   757  C CG2    . VAL A 1 50  ? 18.273  -17.464 28.136  1    19.039 ? 1058 VAL A CG2    1 ? 
ATOM   758  H H      . VAL A 1 50  ? 15.4    -18.773 28.796  1    18.515 ? 1058 VAL A H      1 ? 
ATOM   759  H HA     . VAL A 1 50  ? 17.663  -19.979 27.216  1    17.618 ? 1058 VAL A HA     1 c 
ATOM   760  H HB     . VAL A 1 50  ? 17.745  -18.556 29.891  1    17.745 ? 1058 VAL A HB     1 c 
ATOM   761  H HG11   . VAL A 1 50  ? 19.473  -20.25  29.775  1    17.892 ? 1058 VAL A HG11   1 c 
ATOM   762  H HG12   . VAL A 1 50  ? 19.951  -19.71  28.144  1    17.903 ? 1058 VAL A HG12   1 c 
ATOM   763  H HG13   . VAL A 1 50  ? 20.224  -18.651 29.552  1    17.995 ? 1058 VAL A HG13   1 c 
ATOM   764  H HG21   . VAL A 1 50  ? 18.961  -16.787 28.646  1    18.355 ? 1058 VAL A HG21   1 c 
ATOM   765  H HG22   . VAL A 1 50  ? 18.642  -17.664 27.128  1    18.332 ? 1058 VAL A HG22   1 c 
ATOM   766  H HG23   . VAL A 1 50  ? 17.286  -17     28.075  1    18.362 ? 1058 VAL A HG23   1 c 
ATOM   767  N N      . ILE A 1 51  ? 17.663  -22.126 28.456  1    13.811 ? 1059 ILE A N      1 ? 
ATOM   768  C CA     . ILE A 1 51  ? 17.493  -23.485 28.96   1    16.127 ? 1059 ILE A CA     1 ? 
ATOM   769  C C      . ILE A 1 51  ? 18.857  -24.065 29.306  1    15.969 ? 1059 ILE A C      1 ? 
ATOM   770  O O      . ILE A 1 51  ? 19.752  -24.105 28.455  1    14.015 ? 1059 ILE A O      1 ? 
ATOM   771  C CB     . ILE A 1 51  ? 16.816  -24.361 27.882  1    17.031 ? 1059 ILE A CB     1 ? 
ATOM   772  C CG1    . ILE A 1 51  ? 15.45   -23.804 27.495  1    19.034 ? 1059 ILE A CG1    1 ? 
ATOM   773  C CG2    . ILE A 1 51  ? 16.726  -25.812 28.331  1    19.487 ? 1059 ILE A CG2    1 ? 
ATOM   774  C CD1    . ILE A 1 51  ? 14.913  -24.379 26.199  1    18.343 ? 1059 ILE A CD1    1 ? 
ATOM   775  H H      . ILE A 1 51  ? 18.233  -21.981 27.599  1    14.049 ? 1059 ILE A H      1 ? 
ATOM   776  H HA     . ILE A 1 51  ? 16.867  -23.465 29.855  1    15.782 ? 1059 ILE A HA     1 c 
ATOM   777  H HB     . ILE A 1 51  ? 17.447  -24.329 26.991  1    17.634 ? 1059 ILE A HB     1 c 
ATOM   778  H HG12   . ILE A 1 51  ? 14.741  -24.021 28.297  1    18.418 ? 1059 ILE A HG12   1 c 
ATOM   779  H HG13   . ILE A 1 51  ? 15.523  -22.72  27.395  1    18.379 ? 1059 ILE A HG13   1 c 
ATOM   780  H HG21   . ILE A 1 51  ? 16.168  -26.39  27.592  1    18.742 ? 1059 ILE A HG21   1 c 
ATOM   781  H HG22   . ILE A 1 51  ? 17.729  -26.231 28.433  1    18.732 ? 1059 ILE A HG22   1 c 
ATOM   782  H HG23   . ILE A 1 51  ? 16.211  -25.866 29.293  1    18.684 ? 1059 ILE A HG23   1 c 
ATOM   783  H HD11   . ILE A 1 51  ? 14.783  -25.458 26.3    1    18.525 ? 1059 ILE A HD11   1 c 
ATOM   784  H HD12   . ILE A 1 51  ? 13.951  -23.919 25.967  1    18.523 ? 1059 ILE A HD12   1 c 
ATOM   785  H HD13   . ILE A 1 51  ? 15.617  -24.174 25.389  1    18.491 ? 1059 ILE A HD13   1 c 
ATOM   786  N N      . ASP A 1 52  ? 19.012  -24.531 30.548  1    17.304 ? 1060 ASP A N      1 ? 
ATOM   787  C CA     . ASP A 1 52  ? 20.234  -25.202 30.984  1    15.326 ? 1060 ASP A CA     1 ? 
ATOM   788  C C      . ASP A 1 52  ? 20.124  -26.681 30.624  1    14.864 ? 1060 ASP A C      1 ? 
ATOM   789  O O      . ASP A 1 52  ? 19.305  -27.401 31.206  1    13.942 ? 1060 ASP A O      1 ? 
ATOM   790  C CB     . ASP A 1 52  ? 20.404  -24.991 32.483  1    17.647 ? 1060 ASP A CB     1 ? 
ATOM   791  C CG     . ASP A 1 52  ? 21.646  -25.643 33.063  1    18.718 ? 1060 ASP A CG     1 ? 
ATOM   792  O OD1    . ASP A 1 52  ? 22.311  -26.437 32.385  1    22.705 ? 1060 ASP A OD1    1 ? 
ATOM   793  O OD2    . ASP A 1 52  ? 21.941  -25.332 34.234  1    21.637 ? 1060 ASP A OD2    1 ? 
ATOM   794  H H      . ASP A 1 52  ? 18.206  -24.515 31.203  1    14.379 ? 1060 ASP A H      1 ? 
ATOM   795  H HA     . ASP A 1 52  ? 21.084  -24.764 30.458  1    15.961 ? 1060 ASP A HA     1 c 
ATOM   796  H HB2    . ASP A 1 52  ? 20.454  -23.919 32.687  1    17.325 ? 1060 ASP A HB2    1 c 
ATOM   797  H HB3    . ASP A 1 52  ? 19.531  -25.394 32.999  1    17.334 ? 1060 ASP A HB3    1 c 
ATOM   798  N N      . HIS A 1 53  ? 20.922  -27.121 29.645  1    13.939 ? 1061 HIS A N      1 ? 
ATOM   799  C CA     . HIS A 1 53  ? 21.026  -28.523 29.265  1    13.646 ? 1061 HIS A CA     1 ? 
ATOM   800  C C      . HIS A 1 53  ? 22.253  -29.201 29.874  1    14.197 ? 1061 HIS A C      1 ? 
ATOM   801  O O      . HIS A 1 53  ? 22.472  -30.39  29.635  1    15.017 ? 1061 HIS A O      1 ? 
ATOM   802  C CB     . HIS A 1 53  ? 20.996  -28.717 27.744  1    13.515 ? 1061 HIS A CB     1 ? 
ATOM   803  C CG     . HIS A 1 53  ? 22.177  -28.137 27.025  1    14.063 ? 1061 HIS A CG     1 ? 
ATOM   804  N ND1    . HIS A 1 53  ? 23.329  -28.855 26.786  1    15.289 ? 1061 HIS A ND1    1 ? 
ATOM   805  C CD2    . HIS A 1 53  ? 22.36   -26.918 26.461  1    14.14  ? 1061 HIS A CD2    1 ? 
ATOM   806  C CE1    . HIS A 1 53  ? 24.172  -28.096 26.103  1    15.091 ? 1061 HIS A CE1    1 ? 
ATOM   807  N NE2    . HIS A 1 53  ? 23.611  -26.916 25.904  1    15.059 ? 1061 HIS A NE2    1 ? 
ATOM   808  H H      . HIS A 1 53  ? 21.587  -26.447 29.228  1    14.197 ? 1061 HIS A H      1 ? 
ATOM   809  H HA     . HIS A 1 53  ? 20.142  -29.022 29.665  1    13.799 ? 1061 HIS A HA     1 c 
ATOM   810  H HB2    . HIS A 1 53  ? 20.943  -29.786 27.531  1    13.693 ? 1061 HIS A HB2    1 c 
ATOM   811  H HB3    . HIS A 1 53  ? 20.085  -28.259 27.353  1    13.669 ? 1061 HIS A HB3    1 c 
ATOM   812  H HD2    . HIS A 1 53  ? 21.664  -26.086 26.468  1    14.325 ? 1061 HIS A HD2    1 c 
ATOM   813  H HE1    . HIS A 1 53  ? 25.167  -28.388 25.791  1    15.128 ? 1061 HIS A HE1    1 c 
ATOM   814  H HE2    . HIS A 1 53  ? 24.073  -26.136 25.451  1    15.169 ? 1061 HIS A HE2    1 ? 
ATOM   815  N N      . GLY A 1 54  ? 23.038  -28.466 30.653  1    16.369 ? 1062 GLY A N      1 ? 
ATOM   816  C CA     . GLY A 1 54  ? 24.163  -29.017 31.377  1    17.083 ? 1062 GLY A CA     1 ? 
ATOM   817  C C      . GLY A 1 54  ? 25.321  -29.496 30.521  1    16.133 ? 1062 GLY A C      1 ? 
ATOM   818  O O      . GLY A 1 54  ? 26.208  -30.164 31.044  1    16.109 ? 1062 GLY A O      1 ? 
ATOM   819  H H      . GLY A 1 54  ? 22.793  -27.47  30.787  1    16.591 ? 1062 GLY A H      1 ? 
ATOM   820  H HA2    . GLY A 1 54  ? 24.529  -28.26  32.073  1    16.77  ? 1062 GLY A HA2    1 c 
ATOM   821  H HA3    . GLY A 1 54  ? 23.801  -29.858 31.972  1    16.703 ? 1062 GLY A HA3    1 c 
ATOM   822  N N      . GLY A 1 55  ? 25.341  -29.152 29.232  1    15.219 ? 1063 GLY A N      1 ? 
ATOM   823  C CA     . GLY A 1 55  ? 26.295  -29.736 28.32   1    17.196 ? 1063 GLY A CA     1 ? 
ATOM   824  C C      . GLY A 1 55  ? 25.896  -31.105 27.802  1    17.503 ? 1063 GLY A C      1 ? 
ATOM   825  O O      . GLY A 1 55  ? 26.647  -31.695 27.019  1    18.45  ? 1063 GLY A O      1 ? 
ATOM   826  H H      . GLY A 1 55  ? 24.638  -28.502 28.863  1    14.881 ? 1063 GLY A H      1 ? 
ATOM   827  H HA2    . GLY A 1 55  ? 26.423  -29.059 27.473  1    16.79  ? 1063 GLY A HA2    1 c 
ATOM   828  H HA3    . GLY A 1 55  ? 27.259  -29.813 28.827  1    16.822 ? 1063 GLY A HA3    1 c 
ATOM   829  N N      . ASN A 1 56  ? 24.722  -31.608 28.198  1    17.645 ? 1064 ASN A N      1 ? 
ATOM   830  C CA     . ASN A 1 56  ? 24.268  -32.92  27.771  1    17.112 ? 1064 ASN A CA     1 ? 
ATOM   831  C C      . ASN A 1 56  ? 23.602  -32.912 26.404  1    14.808 ? 1064 ASN A C      1 ? 
ATOM   832  O O      . ASN A 1 56  ? 23.486  -33.978 25.789  1    17.345 ? 1064 ASN A O      1 ? 
ATOM   833  C CB     . ASN A 1 56  ? 23.287  -33.488 28.791  1    16.779 ? 1064 ASN A CB     1 ? 
ATOM   834  C CG     . ASN A 1 56  ? 23.949  -33.723 30.115  1    18.496 ? 1064 ASN A CG     1 ? 
ATOM   835  O OD1    . ASN A 1 56  ? 24.734  -34.671 30.25   1    22.657 ? 1064 ASN A OD1    1 ? 
ATOM   836  N ND2    . ASN A 1 56  ? 23.693  -32.85  31.074  1    18.081 ? 1064 ASN A ND2    1 ? 
ATOM   837  H H      . ASN A 1 56  ? 24.108  -31.019 28.773  1    19.904 ? 1064 ASN A H      1 ? 
ATOM   838  H HA     . ASN A 1 56  ? 25.131  -33.587 27.735  1    16.725 ? 1064 ASN A HA     1 c 
ATOM   839  H HB2    . ASN A 1 56  ? 22.456  -32.792 28.92   1    17.233 ? 1064 ASN A HB2    1 c 
ATOM   840  H HB3    . ASN A 1 56  ? 22.884  -34.431 28.417  1    17.38  ? 1064 ASN A HB3    1 c 
ATOM   841  H HD21   . ASN A 1 56  ? 23.978  -32.997 32.026  1    17.129 ? 1064 ASN A HD21   1 ? 
ATOM   842  H HD22   . ASN A 1 56  ? 23.088  -32.076 30.824  1    16.931 ? 1064 ASN A HD22   1 ? 
ATOM   843  N N      . VAL A 1 57  ? 23.141  -31.753 25.927  1    14.264 ? 1065 VAL A N      1 ? 
ATOM   844  C CA     . VAL A 1 57  ? 22.47   -31.698 24.631  1    16.015 ? 1065 VAL A CA     1 ? 
ATOM   845  C C      . VAL A 1 57  ? 23.139  -30.645 23.746  1    14.821 ? 1065 VAL A C      1 ? 
ATOM   846  O O      . VAL A 1 57  ? 22.504  -29.653 23.351  1    16.369 ? 1065 VAL A O      1 ? 
ATOM   847  C CB     . VAL A 1 57  ? 20.952  -31.492 24.762  1    15.857 ? 1065 VAL A CB     1 ? 
ATOM   848  C CG1    . VAL A 1 57  ? 20.26   -31.982 23.476  1    15.345 ? 1065 VAL A CG1    1 ? 
ATOM   849  C CG2    . VAL A 1 57  ? 20.373  -32.227 25.995  1    18.563 ? 1065 VAL A CG2    1 ? 
ATOM   850  H H      . VAL A 1 57  ? 23.345  -30.865 26.408  1    12.962 ? 1065 VAL A H      1 ? 
ATOM   851  H HA     . VAL A 1 57  ? 22.621  -32.665 24.148  1    15.434 ? 1065 VAL A HA     1 c 
ATOM   852  H HB     . VAL A 1 57  ? 20.769  -30.422 24.876  1    16.241 ? 1065 VAL A HB     1 c 
ATOM   853  H HG11   . VAL A 1 57  ? 20.684  -31.466 22.613  1    15.465 ? 1065 VAL A HG11   1 c 
ATOM   854  H HG12   . VAL A 1 57  ? 20.414  -33.058 23.367  1    15.481 ? 1065 VAL A HG12   1 c 
ATOM   855  H HG13   . VAL A 1 57  ? 19.189  -31.774 23.536  1    15.488 ? 1065 VAL A HG13   1 c 
ATOM   856  H HG21   . VAL A 1 57  ? 19.289  -32.092 26.024  1    17.751 ? 1065 VAL A HG21   1 c 
ATOM   857  H HG22   . VAL A 1 57  ? 20.604  -33.292 25.926  1    17.752 ? 1065 VAL A HG22   1 c 
ATOM   858  H HG23   . VAL A 1 57  ? 20.814  -31.819 26.906  1    17.667 ? 1065 VAL A HG23   1 c 
ATOM   859  N N      . PRO A 1 58  ? 24.418  -30.823 23.404  1    13.629 ? 1066 PRO A N      1 ? 
ATOM   860  C CA     . PRO A 1 58  ? 25.075  -29.869 22.52   1    14.032 ? 1066 PRO A CA     1 ? 
ATOM   861  C C      . PRO A 1 58  ? 24.471  -29.906 21.12   1    13.766 ? 1066 PRO A C      1 ? 
ATOM   862  O O      . PRO A 1 58  ? 23.809  -30.866 20.72   1    14.722 ? 1066 PRO A O      1 ? 
ATOM   863  C CB     . PRO A 1 58  ? 26.526  -30.36  22.489  1    14.234 ? 1066 PRO A CB     1 ? 
ATOM   864  C CG     . PRO A 1 58  ? 26.391  -31.854 22.739  1    14.257 ? 1066 PRO A CG     1 ? 
ATOM   865  C CD     . PRO A 1 58  ? 25.304  -31.947 23.762  1    13.44  ? 1066 PRO A CD     1 ? 
ATOM   866  H HA     . PRO A 1 58  ? 25.011  -28.863 22.937  1    13.966 ? 1066 PRO A HA     1 c 
ATOM   867  H HB2    . PRO A 1 58  ? 26.985  -30.163 21.518  1    14.199 ? 1066 PRO A HB2    1 c 
ATOM   868  H HB3    . PRO A 1 58  ? 27.119  -29.884 23.271  1    14.214 ? 1066 PRO A HB3    1 c 
ATOM   869  H HG2    . PRO A 1 58  ? 26.111  -32.382 21.825  1    14.104 ? 1066 PRO A HG2    1 c 
ATOM   870  H HG3    . PRO A 1 58  ? 27.323  -32.274 23.123  1    14.076 ? 1066 PRO A HG3    1 c 
ATOM   871  H HD2    . PRO A 1 58  ? 24.773  -32.898 23.696  1    13.709 ? 1066 PRO A HD2    1 c 
ATOM   872  H HD3    . PRO A 1 58  ? 25.697  -31.823 24.772  1    13.691 ? 1066 PRO A HD3    1 c 
ATOM   873  N N      . TYR A 1 59  ? 24.766  -28.862 20.354  1    13.643 ? 1067 TYR A N      1 ? 
ATOM   874  C CA     . TYR A 1 59  ? 24.195  -28.679 19.034  1    13.667 ? 1067 TYR A CA     1 ? 
ATOM   875  C C      . TYR A 1 59  ? 25.132  -27.783 18.231  1    13.662 ? 1067 TYR A C      1 ? 
ATOM   876  O O      . TYR A 1 59  ? 26.057  -27.157 18.773  1    12.99  ? 1067 TYR A O      1 ? 
ATOM   877  C CB     . TYR A 1 59  ? 22.788  -28.041 19.108  1    13.488 ? 1067 TYR A CB     1 ? 
ATOM   878  C CG     . TYR A 1 59  ? 22.796  -26.763 19.917  1    12.665 ? 1067 TYR A CG     1 ? 
ATOM   879  C CD1    . TYR A 1 59  ? 23.09   -25.536 19.316  1    13.209 ? 1067 TYR A CD1    1 ? 
ATOM   880  C CD2    . TYR A 1 59  ? 22.575  -26.789 21.29   1    14.455 ? 1067 TYR A CD2    1 ? 
ATOM   881  C CE1    . TYR A 1 59  ? 23.164  -24.374 20.054  1    12.325 ? 1067 TYR A CE1    1 ? 
ATOM   882  C CE2    . TYR A 1 59  ? 22.639  -25.627 22.034  1    14.82  ? 1067 TYR A CE2    1 ? 
ATOM   883  C CZ     . TYR A 1 59  ? 22.943  -24.421 21.424  1    13.465 ? 1067 TYR A CZ     1 ? 
ATOM   884  O OH     . TYR A 1 59  ? 22.987  -23.287 22.196  1    13.246 ? 1067 TYR A OH     1 ? 
ATOM   885  H H      . TYR A 1 59  ? 25.361  -28.11  20.739  1    13.136 ? 1067 TYR A H      1 ? 
ATOM   886  H HA     . TYR A 1 59  ? 24.121  -29.65  18.54   1    13.637 ? 1067 TYR A HA     1 c 
ATOM   887  H HB2    . TYR A 1 59  ? 22.443  -27.825 18.095  1    13.34  ? 1067 TYR A HB2    1 c 
ATOM   888  H HB3    . TYR A 1 59  ? 22.1    -28.754 19.568  1    13.34  ? 1067 TYR A HB3    1 c 
ATOM   889  H HD1    . TYR A 1 59  ? 23.288  -25.499 18.251  1    12.953 ? 1067 TYR A HD1    1 c 
ATOM   890  H HD2    . TYR A 1 59  ? 22.36   -27.731 21.783  1    14.115 ? 1067 TYR A HD2    1 c 
ATOM   891  H HE1    . TYR A 1 59  ? 23.389  -23.43  19.569  1    12.78  ? 1067 TYR A HE1    1 c 
ATOM   892  H HE2    . TYR A 1 59  ? 22.462  -25.659 23.104  1    14.394 ? 1067 TYR A HE2    1 c 
ATOM   893  H HH     . TYR A 1 59  ? 23.597  -22.643 21.8    1    13.66  ? 1067 TYR A HH     1 ? 
ATOM   894  N N      . TRP A 1 60  ? 24.86   -27.696 16.928  1    13.54  ? 1068 TRP A N      1 ? 
ATOM   895  C CA     . TRP A 1 60  ? 25.5    -26.729 16.06   1    15.369 ? 1068 TRP A CA     1 ? 
ATOM   896  C C      . TRP A 1 60  ? 24.499  -25.633 15.719  1    15.972 ? 1068 TRP A C      1 ? 
ATOM   897  O O      . TRP A 1 60  ? 23.28   -25.82  15.757  1    16.995 ? 1068 TRP A O      1 ? 
ATOM   898  C CB     . TRP A 1 60  ? 26      -27.374 14.763  1    15.554 ? 1068 TRP A CB     1 ? 
ATOM   899  C CG     . TRP A 1 60  ? 27.219  -28.23  14.93   1    17.339 ? 1068 TRP A CG     1 ? 
ATOM   900  C CD1    . TRP A 1 60  ? 27.806  -28.625 16.096  1    18.213 ? 1068 TRP A CD1    1 ? 
ATOM   901  C CD2    . TRP A 1 60  ? 27.991  -28.791 13.867  1    17.336 ? 1068 TRP A CD2    1 ? 
ATOM   902  N NE1    . TRP A 1 60  ? 28.911  -29.402 15.82   1    18.473 ? 1068 TRP A NE1    1 ? 
ATOM   903  C CE2    . TRP A 1 60  ? 29.041  -29.521 14.462  1    20.238 ? 1068 TRP A CE2    1 ? 
ATOM   904  C CE3    . TRP A 1 60  ? 27.904  -28.739 12.473  1    20.758 ? 1068 TRP A CE3    1 ? 
ATOM   905  C CZ2    . TRP A 1 60  ? 29.994  -30.192 13.705  1    21.703 ? 1068 TRP A CZ2    1 ? 
ATOM   906  C CZ3    . TRP A 1 60  ? 28.846  -29.412 11.724  1    20.513 ? 1068 TRP A CZ3    1 ? 
ATOM   907  C CH2    . TRP A 1 60  ? 29.88   -30.129 12.338  1    22.444 ? 1068 TRP A CH2    1 ? 
ATOM   908  H H      . TRP A 1 60  ? 24.128  -28.305 16.52   1    13.525 ? 1068 TRP A H      1 ? 
ATOM   909  H HA     . TRP A 1 60  ? 26.349  -26.287 16.583  1    15.116 ? 1068 TRP A HA     1 c 
ATOM   910  H HB2    . TRP A 1 60  ? 25.195  -27.984 14.347  1    15.892 ? 1068 TRP A HB2    1 c 
ATOM   911  H HB3    . TRP A 1 60  ? 26.221  -26.581 14.045  1    15.892 ? 1068 TRP A HB3    1 c 
ATOM   912  H HD1    . TRP A 1 60  ? 27.473  -28.369 17.094  1    17.998 ? 1068 TRP A HD1    1 c 
ATOM   913  H HE1    . TRP A 1 60  ? 29.545  -29.818 16.472  1    19.606 ? 1068 TRP A HE1    1 ? 
ATOM   914  H HE3    . TRP A 1 60  ? 27.104  -28.187 11.991  1    19.926 ? 1068 TRP A HE3    1 c 
ATOM   915  H HZ2    . TRP A 1 60  ? 30.794  -30.75  14.178  1    21.471 ? 1068 TRP A HZ2    1 c 
ATOM   916  H HZ3    . TRP A 1 60  ? 28.787  -29.384 10.641  1    20.943 ? 1068 TRP A HZ3    1 c 
ATOM   917  H HH2    . TRP A 1 60  ? 30.606  -30.648 11.722  1    21.792 ? 1068 TRP A HH2    1 c 
ATOM   918  N N      . GLU A 1 61  ? 25.036  -24.463 15.366  1    14.676 ? 1069 GLU A N      1 ? 
ATOM   919  C CA     . GLU A 1 61  ? 24.197  -23.35  14.967  1    14.705 ? 1069 GLU A CA     1 ? 
ATOM   920  C C      . GLU A 1 61  ? 23.304  -23.763 13.799  1    15.022 ? 1069 GLU A C      1 ? 
ATOM   921  O O      . GLU A 1 61  ? 23.726  -24.481 12.899  1    13.713 ? 1069 GLU A O      1 ? 
ATOM   922  C CB     . GLU A 1 61  ? 25.075  -22.16  14.584  1    15.194 ? 1069 GLU A CB     1 ? 
ATOM   923  C CG     . GLU A 1 61  ? 25.853  -21.542 15.754  1    15.471 ? 1069 GLU A CG     1 ? 
ATOM   924  C CD     . GLU A 1 61  ? 27.1    -22.332 16.186  1    13.312 ? 1069 GLU A CD     1 ? 
ATOM   925  O OE1    . GLU A 1 61  ? 27.572  -23.202 15.424  1    13.651 ? 1069 GLU A OE1    1 ? 
ATOM   926  O OE2    . GLU A 1 61  ? 27.602  -22.072 17.307  1    13.102 ? 1069 GLU A OE2    1 ? 
ATOM   927  H H      . GLU A 1 61  ? 26.062  -24.343 15.269  1    13.934 ? 1069 GLU A H      1 ? 
ATOM   928  H HA     . GLU A 1 61  ? 23.566  -23.074 15.813  1    14.892 ? 1069 GLU A HA     1 c 
ATOM   929  H HB2    . GLU A 1 61  ? 25.78   -22.48  13.815  1    15.172 ? 1069 GLU A HB2    1 c 
ATOM   930  H HB3    . GLU A 1 61  ? 24.441  -21.386 14.147  1    15.15  ? 1069 GLU A HB3    1 c 
ATOM   931  H HG2    . GLU A 1 61  ? 26.163  -20.532 15.478  1    14.907 ? 1069 GLU A HG2    1 c 
ATOM   932  H HG3    . GLU A 1 61  ? 25.185  -21.457 16.612  1    14.885 ? 1069 GLU A HG3    1 c 
ATOM   933  N N      . GLY A 1 62  ? 22.038  -23.323 13.852  1    16.94  ? 1070 GLY A N      1 ? 
ATOM   934  C CA     . GLY A 1 62  ? 21.08   -23.648 12.812  1    16.501 ? 1070 GLY A CA     1 ? 
ATOM   935  C C      . GLY A 1 62  ? 20.205  -24.85  13.114  1    15.439 ? 1070 GLY A C      1 ? 
ATOM   936  O O      . GLY A 1 62  ? 19.202  -25.056 12.414  1    16.027 ? 1070 GLY A O      1 ? 
ATOM   937  H H      . GLY A 1 62  ? 21.77   -22.634 14.575  1    16.602 ? 1070 GLY A H      1 ? 
ATOM   938  H HA2    . GLY A 1 62  ? 20.439  -22.778 12.652  1    16.356 ? 1070 GLY A HA2    1 c 
ATOM   939  H HA3    . GLY A 1 62  ? 21.619  -23.828 11.883  1    16.327 ? 1070 GLY A HA3    1 c 
ATOM   940  N N      . GLN A 1 63  ? 20.533  -25.644 14.14   1    13.102 ? 1071 GLN A N      1 ? 
ATOM   941  C CA     . GLN A 1 63  ? 19.727  -26.8   14.493  1    13.39  ? 1071 GLN A CA     1 ? 
ATOM   942  C C      . GLN A 1 63  ? 18.519  -26.383 15.333  1    12.889 ? 1071 GLN A C      1 ? 
ATOM   943  O O      . GLN A 1 63  ? 18.391  -25.23  15.75   1    14.47  ? 1071 GLN A O      1 ? 
ATOM   944  C CB     . GLN A 1 63  ? 20.582  -27.836 15.213  1    12.058 ? 1071 GLN A CB     1 ? 
ATOM   945  C CG     . GLN A 1 63  ? 21.67   -28.426 14.324  1    13.272 ? 1071 GLN A CG     1 ? 
ATOM   946  C CD     . GLN A 1 63  ? 22.278  -29.657 14.949  1    14.283 ? 1071 GLN A CD     1 ? 
ATOM   947  O OE1    . GLN A 1 63  ? 23.011  -29.568 15.928  1    13.966 ? 1071 GLN A OE1    1 ? 
ATOM   948  N NE2    . GLN A 1 63  ? 21.931  -30.825 14.42   1    15.575 ? 1071 GLN A NE2    1 ? 
ATOM   949  H H      . GLN A 1 63  ? 21.366  -25.434 14.716  1    12.681 ? 1071 GLN A H      1 ? 
ATOM   950  H HA     . GLN A 1 63  ? 19.36   -27.251 13.569  1    13.016 ? 1071 GLN A HA     1 c 
ATOM   951  H HB2    . GLN A 1 63  ? 21.047  -27.368 16.084  1    12.598 ? 1071 GLN A HB2    1 c 
ATOM   952  H HB3    . GLN A 1 63  ? 19.937  -28.641 15.571  1    12.6   ? 1071 GLN A HB3    1 c 
ATOM   953  H HG2    . GLN A 1 63  ? 21.246  -28.685 13.353  1    13.259 ? 1071 GLN A HG2    1 c 
ATOM   954  H HG3    . GLN A 1 63  ? 22.452  -27.681 14.161  1    13.238 ? 1071 GLN A HG3    1 c 
ATOM   955  H HE21   . GLN A 1 63  ? 21.293  -30.852 13.634  1    15.166 ? 1071 GLN A HE21   1 ? 
ATOM   956  H HE22   . GLN A 1 63  ? 22.305  -31.685 14.804  1    15.14  ? 1071 GLN A HE22   1 ? 
ATOM   957  N N      . SER A 1 64  ? 17.643  -27.353 15.596  1    13.22  ? 1072 SER A N      1 ? 
ATOM   958  C CA     . SER A 1 64  ? 16.458  -27.156 16.42   1    14.674 ? 1072 SER A CA     1 ? 
ATOM   959  C C      . SER A 1 64  ? 16.483  -28.083 17.631  1    14.256 ? 1072 SER A C      1 ? 
ATOM   960  O O      . SER A 1 64  ? 17.03   -29.191 17.575  1    13.898 ? 1072 SER A O      1 ? 
ATOM   961  C CB     . SER A 1 64  ? 15.181  -27.458 15.627  1    15.332 ? 1072 SER A CB     1 ? 
ATOM   962  O OG     . SER A 1 64  ? 14.974  -26.491 14.618  1    16.284 ? 1072 SER A OG     1 ? 
ATOM   963  H H      . SER A 1 64  ? 17.817  -28.282 15.193  1    13.523 ? 1072 SER A H      1 ? 
ATOM   964  H HA     . SER A 1 64  ? 16.431  -26.121 16.765  1    14.43  ? 1072 SER A HA     1 c 
ATOM   965  H HB2    . SER A 1 64  ? 15.263  -28.447 15.173  1    15.405 ? 1072 SER A HB2    1 c 
ATOM   966  H HB3    . SER A 1 64  ? 14.326  -27.463 16.307  1    15.405 ? 1072 SER A HB3    1 c 
ATOM   967  H HG     . SER A 1 64  ? 15.648  -26.646 13.953  1    16.245 ? 1072 SER A HG     1 ? 
ATOM   968  N N      . TYR A 1 65  ? 15.86   -27.629 18.716  1    13.708 ? 1073 TYR A N      1 ? 
ATOM   969  C CA     . TYR A 1 65  ? 15.525  -28.499 19.832  1    14.44  ? 1073 TYR A CA     1 ? 
ATOM   970  C C      . TYR A 1 65  ? 14.062  -28.911 19.712  1    15.766 ? 1073 TYR A C      1 ? 
ATOM   971  O O      . TYR A 1 65  ? 13.223  -28.139 19.238  1    15.61  ? 1073 TYR A O      1 ? 
ATOM   972  C CB     . TYR A 1 65  ? 15.667  -27.742 21.147  1    14.099 ? 1073 TYR A CB     1 ? 
ATOM   973  C CG     . TYR A 1 65  ? 17.042  -27.716 21.804  1    14.539 ? 1073 TYR A CG     1 ? 
ATOM   974  C CD1    . TYR A 1 65  ? 17.94   -28.782 21.706  1    15.054 ? 1073 TYR A CD1    1 ? 
ATOM   975  C CD2    . TYR A 1 65  ? 17.406  -26.635 22.586  1    14.735 ? 1073 TYR A CD2    1 ? 
ATOM   976  C CE1    . TYR A 1 65  ? 19.174  -28.749 22.366  1    13.035 ? 1073 TYR A CE1    1 ? 
ATOM   977  C CE2    . TYR A 1 65  ? 18.62   -26.599 23.253  1    14.101 ? 1073 TYR A CE2    1 ? 
ATOM   978  C CZ     . TYR A 1 65  ? 19.499  -27.649 23.143  1    13.929 ? 1073 TYR A CZ     1 ? 
ATOM   979  O OH     . TYR A 1 65  ? 20.679  -27.594 23.854  1    14.325 ? 1073 TYR A OH     1 ? 
ATOM   980  H H      . TYR A 1 65  ? 15.476  -26.663 18.72   1    14.029 ? 1073 TYR A H      1 ? 
ATOM   981  H HA     . TYR A 1 65  ? 16.165  -29.381 19.829  1    14.462 ? 1073 TYR A HA     1 c 
ATOM   982  H HB2    . TYR A 1 65  ? 15.351  -26.711 20.975  1    14.271 ? 1073 TYR A HB2    1 c 
ATOM   983  H HB3    . TYR A 1 65  ? 14.958  -28.171 21.859  1    14.278 ? 1073 TYR A HB3    1 c 
ATOM   984  H HD1    . TYR A 1 65  ? 17.679  -29.65  21.11   1    14.468 ? 1073 TYR A HD1    1 c 
ATOM   985  H HD2    . TYR A 1 65  ? 16.716  -25.805 22.699  1    14.538 ? 1073 TYR A HD2    1 c 
ATOM   986  H HE1    . TYR A 1 65  ? 19.861  -29.584 22.288  1    13.691 ? 1073 TYR A HE1    1 c 
ATOM   987  H HE2    . TYR A 1 65  ? 18.877  -25.742 23.867  1    14.199 ? 1073 TYR A HE2    1 c 
ATOM   988  H HH     . TYR A 1 65  ? 21.214  -28.397 23.669  1    12.721 ? 1073 TYR A HH     1 ? 
ATOM   989  N N      . GLY A 1 66  ? 13.749  -30.118 20.177  1    16.033 ? 1074 GLY A N      1 ? 
ATOM   990  C CA     . GLY A 1 66  ? 12.374  -30.503 20.417  1    19.725 ? 1074 GLY A CA     1 ? 
ATOM   991  C C      . GLY A 1 66  ? 12.004  -30.263 21.871  1    17.989 ? 1074 GLY A C      1 ? 
ATOM   992  O O      . GLY A 1 66  ? 12.831  -30.422 22.775  1    19.206 ? 1074 GLY A O      1 ? 
ATOM   993  H H      . GLY A 1 66  ? 14.513  -30.763 20.451  1    16.839 ? 1074 GLY A H      1 ? 
ATOM   994  H HA2    . GLY A 1 66  ? 11.714  -29.93  19.764  1    18.399 ? 1074 GLY A HA2    1 c 
ATOM   995  H HA3    . GLY A 1 66  ? 12.257  -31.56  20.178  1    18.457 ? 1074 GLY A HA3    1 c 
ATOM   996  N N      . VAL A 1 67  ? 10.749  -29.872 22.096  1    16.631 ? 1075 VAL A N      1 ? 
ATOM   997  C CA     . VAL A 1 67  ? 10.199  -29.748 23.437  1    16.093 ? 1075 VAL A CA     1 ? 
ATOM   998  C C      . VAL A 1 67  ? 8.909   -30.554 23.475  1    15.588 ? 1075 VAL A C      1 ? 
ATOM   999  O O      . VAL A 1 67  ? 8.064   -30.437 22.576  1    14.57  ? 1075 VAL A O      1 ? 
ATOM   1000 C CB     . VAL A 1 67  ? 9.924   -28.28  23.814  1    17.823 ? 1075 VAL A CB     1 ? 
ATOM   1001 C CG1    . VAL A 1 67  ? 9.277   -28.185 25.18   1    17.228 ? 1075 VAL A CG1    1 ? 
ATOM   1002 C CG2    . VAL A 1 67  ? 11.208  -27.461 23.78   1    18.069 ? 1075 VAL A CG2    1 ? 
ATOM   1003 H H      . VAL A 1 67  ? 10.122  -29.644 21.297  1    17.037 ? 1075 VAL A H      1 ? 
ATOM   1004 H HA     . VAL A 1 67  ? 10.906  -30.172 24.15   1    16.407 ? 1075 VAL A HA     1 c 
ATOM   1005 H HB     . VAL A 1 67  ? 9.233   -27.874 23.073  1    17.436 ? 1075 VAL A HB     1 c 
ATOM   1006 H HG11   . VAL A 1 67  ? 9.893   -28.711 25.913  1    17.381 ? 1075 VAL A HG11   1 c 
ATOM   1007 H HG12   . VAL A 1 67  ? 9.187   -27.136 25.469  1    17.381 ? 1075 VAL A HG12   1 c 
ATOM   1008 H HG13   . VAL A 1 67  ? 8.284   -28.639 25.149  1    17.345 ? 1075 VAL A HG13   1 c 
ATOM   1009 H HG21   . VAL A 1 67  ? 11.927  -27.88  24.487  1    17.99  ? 1075 VAL A HG21   1 c 
ATOM   1010 H HG22   . VAL A 1 67  ? 11.631  -27.487 22.773  1    17.984 ? 1075 VAL A HG22   1 c 
ATOM   1011 H HG23   . VAL A 1 67  ? 10.989  -26.427 24.055  1    17.963 ? 1075 VAL A HG23   1 c 
ATOM   1012 N N      . ILE A 1 68  ? 8.754   -31.375 24.511  1    14.815 ? 1076 ILE A N      1 ? 
ATOM   1013 C CA     . ILE A 1 68  ? 7.531   -32.134 24.731  1    15.497 ? 1076 ILE A CA     1 ? 
ATOM   1014 C C      . ILE A 1 68  ? 6.782   -31.441 25.863  1    14.737 ? 1076 ILE A C      1 ? 
ATOM   1015 O O      . ILE A 1 68  ? 7.207   -31.541 27.022  1    15.336 ? 1076 ILE A O      1 ? 
ATOM   1016 C CB     . ILE A 1 68  ? 7.814   -33.602 25.074  1    16.859 ? 1076 ILE A CB     1 ? 
ATOM   1017 C CG1    . ILE A 1 68  ? 8.503   -34.295 23.898  1    18.034 ? 1076 ILE A CG1    1 ? 
ATOM   1018 C CG2    . ILE A 1 68  ? 6.52    -34.327 25.432  1    15.651 ? 1076 ILE A CG2    1 ? 
ATOM   1019 C CD1    . ILE A 1 68  ? 9.064   -35.664 24.218  1    17.619 ? 1076 ILE A CD1    1 ? 
ATOM   1020 H H      . ILE A 1 68  ? 9.502   -31.444 25.23   1    14.724 ? 1076 ILE A H      1 ? 
ATOM   1021 H HA     . ILE A 1 68  ? 6.925   -32.098 23.826  1    15.459 ? 1076 ILE A HA     1 c 
ATOM   1022 H HB     . ILE A 1 68  ? 8.484   -33.635 25.936  1    16.587 ? 1076 ILE A HB     1 c 
ATOM   1023 H HG12   . ILE A 1 68  ? 7.784   -34.395 23.083  1    17.677 ? 1076 ILE A HG12   1 c 
ATOM   1024 H HG13   . ILE A 1 68  ? 9.318   -33.659 23.547  1    17.662 ? 1076 ILE A HG13   1 c 
ATOM   1025 H HG21   . ILE A 1 68  ? 6.722   -35.391 25.567  1    16.013 ? 1076 ILE A HG21   1 c 
ATOM   1026 H HG22   . ILE A 1 68  ? 6.114   -33.918 26.359  1    16.026 ? 1076 ILE A HG22   1 c 
ATOM   1027 H HG23   . ILE A 1 68  ? 5.793   -34.196 24.629  1    16.004 ? 1076 ILE A HG23   1 c 
ATOM   1028 H HD11   . ILE A 1 68  ? 8.254   -36.338 24.507  1    17.786 ? 1076 ILE A HD11   1 c 
ATOM   1029 H HD12   . ILE A 1 68  ? 9.569   -36.064 23.336  1    17.785 ? 1076 ILE A HD12   1 c 
ATOM   1030 H HD13   . ILE A 1 68  ? 9.779   -35.583 25.039  1    17.739 ? 1076 ILE A HD13   1 c 
ATOM   1031 N N      . PRO A 1 69  ? 5.7     -30.717 25.587  1    14.715 ? 1077 PRO A N      1 ? 
ATOM   1032 C CA     . PRO A 1 69  ? 4.969   -30.063 26.659  1    14.348 ? 1077 PRO A CA     1 ? 
ATOM   1033 C C      . PRO A 1 69  ? 4.274   -31.089 27.531  1    15.014 ? 1077 PRO A C      1 ? 
ATOM   1034 O O      . PRO A 1 69  ? 4.078   -32.24  27.11   1    19.181 ? 1077 PRO A O      1 ? 
ATOM   1035 C CB     . PRO A 1 69  ? 3.983   -29.163 25.93   1    14.385 ? 1077 PRO A CB     1 ? 
ATOM   1036 C CG     . PRO A 1 69  ? 3.697   -29.944 24.658  1    15.686 ? 1077 PRO A CG     1 ? 
ATOM   1037 C CD     . PRO A 1 69  ? 5.025   -30.555 24.276  1    16.095 ? 1077 PRO A CD     1 ? 
ATOM   1038 H HA     . PRO A 1 69  ? 5.656   -29.465 27.26   1    14.554 ? 1077 PRO A HA     1 c 
ATOM   1039 H HB2    . PRO A 1 69  ? 3.074   -29.018 26.517  1    14.648 ? 1077 PRO A HB2    1 c 
ATOM   1040 H HB3    . PRO A 1 69  ? 4.43    -28.192 25.704  1    14.648 ? 1077 PRO A HB3    1 c 
ATOM   1041 H HG2    . PRO A 1 69  ? 2.952   -30.722 24.838  1    15.482 ? 1077 PRO A HG2    1 c 
ATOM   1042 H HG3    . PRO A 1 69  ? 3.335   -29.283 23.868  1    15.482 ? 1077 PRO A HG3    1 c 
ATOM   1043 H HD2    . PRO A 1 69  ? 4.893   -31.521 23.785  1    15.691 ? 1077 PRO A HD2    1 c 
ATOM   1044 H HD3    . PRO A 1 69  ? 5.597   -29.892 23.624  1    15.692 ? 1077 PRO A HD3    1 c 
ATOM   1045 N N      . PRO A 1 70  ? 3.915   -30.729 28.763  1    16.249 ? 1078 PRO A N      1 ? 
ATOM   1046 C CA     . PRO A 1 70  ? 3.29    -31.696 29.642  1    17.214 ? 1078 PRO A CA     1 ? 
ATOM   1047 C C      . PRO A 1 70  ? 1.877   -32.069 29.224  1    18.422 ? 1078 PRO A C      1 ? 
ATOM   1048 O O      . PRO A 1 70  ? 1.247   -31.409 28.391  1    18.136 ? 1078 PRO A O      1 ? 
ATOM   1049 C CB     . PRO A 1 70  ? 3.169   -31.02  31.011  1    17.15  ? 1078 PRO A CB     1 ? 
ATOM   1050 C CG     . PRO A 1 70  ? 3.779   -29.641 30.859  1    15.774 ? 1078 PRO A CG     1 ? 
ATOM   1051 C CD     . PRO A 1 70  ? 3.972   -29.385 29.348  1    15.102 ? 1078 PRO A CD     1 ? 
ATOM   1052 H HA     . PRO A 1 70  ? 3.909   -32.592 29.712  1    17.223 ? 1078 PRO A HA     1 c 
ATOM   1053 H HB2    . PRO A 1 70  ? 2.122   -30.945 31.313  1    16.864 ? 1078 PRO A HB2    1 c 
ATOM   1054 H HB3    . PRO A 1 70  ? 3.703   -31.594 31.771  1    16.857 ? 1078 PRO A HB3    1 c 
ATOM   1055 H HG2    . PRO A 1 70  ? 3.119   -28.884 31.287  1    15.916 ? 1078 PRO A HG2    1 c 
ATOM   1056 H HG3    . PRO A 1 70  ? 4.74    -29.591 31.375  1    15.915 ? 1078 PRO A HG3    1 c 
ATOM   1057 H HD2    . PRO A 1 70  ? 3.176   -28.755 28.946  1    15.549 ? 1078 PRO A HD2    1 c 
ATOM   1058 H HD3    . PRO A 1 70  ? 4.937   -28.916 29.147  1    15.49  ? 1078 PRO A HD3    1 c 
ATOM   1059 N N      . GLY A 1 71  ? 1.392   -33.163 29.819  1    18.623 ? 1079 GLY A N      1 ? 
ATOM   1060 C CA     . GLY A 1 71  ? 0.013   -33.583 29.599  1    21.038 ? 1079 GLY A CA     1 ? 
ATOM   1061 C C      . GLY A 1 71  ? -0.091  -34.766 28.64   1    22.417 ? 1079 GLY A C      1 ? 
ATOM   1062 O O      . GLY A 1 71  ? 0.876   -35.224 28.045  1    22.282 ? 1079 GLY A O      1 ? 
ATOM   1063 H H      . GLY A 1 71  ? 2.008   -33.732 30.427  0.5  16.94  ? 1079 GLY A H      1 ? 
ATOM   1064 H HA2    . GLY A 1 71  ? -0.427  -33.86  30.557  1    20.74  ? 1079 GLY A HA2    1 c 
ATOM   1065 H HA3    . GLY A 1 71  ? -0.559  -32.743 29.201  1    20.741 ? 1079 GLY A HA3    1 c 
ATOM   1066 N N      . GLU A 1 72  ? -1.307  -35.255 28.51   1    27.516 ? 1080 GLU A N      1 ? 
ATOM   1067 C CA     . GLU A 1 72  ? -1.623  -36.352 27.623  1    30.917 ? 1080 GLU A CA     1 ? 
ATOM   1068 C C      . GLU A 1 72  ? -1.835  -35.833 26.192  1    32.854 ? 1080 GLU A C      1 ? 
ATOM   1069 O O      . GLU A 1 72  ? -2.316  -34.719 25.981  1    28.217 ? 1080 GLU A O      1 ? 
ATOM   1070 C CB     . GLU A 1 72  ? -2.864  -36.937 28.307  1    38.414 ? 1080 GLU A CB     1 ? 
ATOM   1071 C CG     . GLU A 1 72  ? -3.915  -37.568 27.397  1    45.545 ? 1080 GLU A CG     1 ? 
ATOM   1072 C CD     . GLU A 1 72  ? -4.591  -38.761 28.059  1    47.251 ? 1080 GLU A CD     1 ? 
ATOM   1073 O OE1    . GLU A 1 72  ? -5.83   -38.78  28.204  1    51.602 ? 1080 GLU A OE1    1 ? 
ATOM   1074 O OE2    . GLU A 1 72  ? -3.839  -39.691 28.426  1    45.902 ? 1080 GLU A OE2    1 ? 
ATOM   1075 H H      . GLU A 1 72  ? -2.082  -34.794 29.016  1    27.404 ? 1080 GLU A H      1 ? 
ATOM   1076 H HA     . GLU A 1 72  ? -0.802  -37.072 27.638  1    31.674 ? 1080 GLU A HA     1 c 
ATOM   1077 H HB2    . GLU A 1 72  ? -2.538  -37.684 29.033  1    38.082 ? 1080 GLU A HB2    1 c 
ATOM   1078 H HB3    . GLU A 1 72  ? -3.367  -36.143 28.859  1    37.869 ? 1080 GLU A HB3    1 c 
ATOM   1079 H HG2    . GLU A 1 72  ? -4.674  -36.824 27.146  1    44.21  ? 1080 GLU A HG2    1 c 
ATOM   1080 H HG3    . GLU A 1 72  ? -3.443  -37.901 26.471  1    44.069 ? 1080 GLU A HG3    1 c 
ATOM   1081 N N      . ASN A 1 73  ? -1.497  -36.667 25.185  1    28.865 ? 1081 ASN A N      1 ? 
ATOM   1082 C CA     . ASN A 1 73  ? -1.854  -36.376 23.799  1    32.78  ? 1081 ASN A CA     1 ? 
ATOM   1083 C C      . ASN A 1 73  ? -3.373  -36.47  23.651  1    31.388 ? 1081 ASN A C      1 ? 
ATOM   1084 O O      . ASN A 1 73  ? -3.927  -37.533 23.93   1    33.164 ? 1081 ASN A O      1 ? 
ATOM   1085 C CB     . ASN A 1 73  ? -1.222  -37.385 22.842  1    32.545 ? 1081 ASN A CB     1 ? 
ATOM   1086 C CG     . ASN A 1 73  ? -1.373  -37     21.384  1    35.32  ? 1081 ASN A CG     1 ? 
ATOM   1087 O OD1    . ASN A 1 73  ? -2.411  -36.465 20.983  1    34.192 ? 1081 ASN A OD1    1 ? 
ATOM   1088 N ND2    . ASN A 1 73  ? -0.343  -37.222 20.575  1    37.347 ? 1081 ASN A ND2    1 ? 
ATOM   1089 H H      . ASN A 1 73  ? -1.032  -37.57  25.403  1    25.489 ? 1081 ASN A H      1 ? 
ATOM   1090 H HA     . ASN A 1 73  ? -1.505  -35.376 23.534  1    31.763 ? 1081 ASN A HA     1 c 
ATOM   1091 H HB2    . ASN A 1 73  ? -0.161  -37.477 23.075  1    33.226 ? 1081 ASN A HB2    1 c 
ATOM   1092 H HB3    . ASN A 1 73  ? -1.684  -38.362 23.001  1    33.441 ? 1081 ASN A HB3    1 c 
ATOM   1093 H HD21   . ASN A 1 73  ? -0.485  -37.111 19.581  1    36.972 ? 1081 ASN A HD21   1 ? 
ATOM   1094 H HD22   . ASN A 1 73  ? 0.568   -37.537 20.935  1    38.564 ? 1081 ASN A HD22   1 ? 
ATOM   1095 N N      . PRO A 1 74  ? -4.117  -35.411 23.261  1    34.266 ? 1082 PRO A N      1 ? 
ATOM   1096 C CA     . PRO A 1 74  ? -5.578  -35.543 23.166  1    41.822 ? 1082 PRO A CA     1 ? 
ATOM   1097 C C      . PRO A 1 74  ? -6.037  -36.609 22.161  1    44.75  ? 1082 PRO A C      1 ? 
ATOM   1098 O O      . PRO A 1 74  ? -7.147  -37.145 22.258  1    43.605 ? 1082 PRO A O      1 ? 
ATOM   1099 C CB     . PRO A 1 74  ? -6.076  -34.133 22.774  1    36.805 ? 1082 PRO A CB     1 ? 
ATOM   1100 C CG     . PRO A 1 74  ? -4.911  -33.206 23.033  1    34.455 ? 1082 PRO A CG     1 ? 
ATOM   1101 C CD     . PRO A 1 74  ? -3.647  -34.051 22.954  1    34.528 ? 1082 PRO A CD     1 ? 
ATOM   1102 H HA     . PRO A 1 74  ? -5.974  -35.793 24.152  1    39.873 ? 1082 PRO A HA     1 c 
ATOM   1103 H HB2    . PRO A 1 74  ? -6.365  -34.105 21.721  1    37.277 ? 1082 PRO A HB2    1 c 
ATOM   1104 H HB3    . PRO A 1 74  ? -6.939  -33.847 23.378  1    37.277 ? 1082 PRO A HB3    1 c 
ATOM   1105 H HG2    . PRO A 1 74  ? -4.881  -32.41  22.286  1    34.962 ? 1082 PRO A HG2    1 c 
ATOM   1106 H HG3    . PRO A 1 74  ? -4.999  -32.75  24.021  1    34.933 ? 1082 PRO A HG3    1 c 
ATOM   1107 H HD2    . PRO A 1 74  ? -3.208  -34.012 21.955  1    34.441 ? 1082 PRO A HD2    1 c 
ATOM   1108 H HD3    . PRO A 1 74  ? -2.906  -33.724 23.686  1    34.392 ? 1082 PRO A HD3    1 c 
ATOM   1109 N N      . LYS A 1 75  ? -5.175  -36.884 21.178  1    42.119 ? 1083 LYS A N      1 ? 
ATOM   1110 C CA     . LYS A 1 75  ? -5.475  -37.81  20.098  1    47.907 ? 1083 LYS A CA     1 ? 
ATOM   1111 C C      . LYS A 1 75  ? -4.932  -39.213 20.368  1    52.481 ? 1083 LYS A C      1 ? 
ATOM   1112 O O      . LYS A 1 75  ? -5.026  -40.075 19.494  1    58.754 ? 1083 LYS A O      1 ? 
ATOM   1113 C CB     . LYS A 1 75  ? -4.871  -37.239 18.808  1    51.893 ? 1083 LYS A CB     1 ? 
ATOM   1114 C CG     . LYS A 1 75  ? -5.269  -35.783 18.535  1    59.266 ? 1083 LYS A CG     1 ? 
ATOM   1115 C CD     . LYS A 1 75  ? -4.517  -35.102 17.398  1    64.755 ? 1083 LYS A CD     1 ? 
ATOM   1116 C CE     . LYS A 1 75  ? -4.913  -33.67  17.278  1    69.671 ? 1083 LYS A CE     1 ? 
ATOM   1117 N NZ     . LYS A 1 75  ? -4.441  -33.111 16.007  1    79.219 ? 1083 LYS A NZ     1 ? 
ATOM   1118 H H      . LYS A 1 75  ? -4.287  -36.356 21.139  1    41.744 ? 1083 LYS A H      1 ? 
ATOM   1119 H HA     . LYS A 1 75  ? -6.559  -37.87  19.984  1    48.158 ? 1083 LYS A HA     1 c 
ATOM   1120 H HB2    . LYS A 1 75  ? -3.783  -37.298 18.869  1    52.501 ? 1083 LYS A HB2    1 c 
ATOM   1121 H HB3    . LYS A 1 75  ? -5.193  -37.852 17.963  1    52.501 ? 1083 LYS A HB3    1 c 
ATOM   1122 H HG2    . LYS A 1 75  ? -6.338  -35.757 18.313  1    58.672 ? 1083 LYS A HG2    1 c 
ATOM   1123 H HG3    . LYS A 1 75  ? -5.112  -35.207 19.449  1    58.571 ? 1083 LYS A HG3    1 c 
ATOM   1124 H HD2    . LYS A 1 75  ? -3.443  -35.165 17.585  1    64.568 ? 1083 LYS A HD2    1 c 
ATOM   1125 H HD3    . LYS A 1 75  ? -4.735  -35.617 16.46   1    64.568 ? 1083 LYS A HD3    1 c 
ATOM   1126 H HE2    . LYS A 1 75  ? -6      -33.583 17.327  1    70.539 ? 1083 LYS A HE2    1 c 
ATOM   1127 H HE3    . LYS A 1 75  ? -4.483  -33.098 18.103  1    70.393 ? 1083 LYS A HE3    1 c 
ATOM   1128 H HZ1    . LYS A 1 75  ? -4.799  -32.161 15.887  1    77.591 ? 1083 LYS A HZ1    1 ? 
ATOM   1129 H HZ2    . LYS A 1 75  ? -3.423  -33.09  15.997  1    77.064 ? 1083 LYS A HZ2    1 ? 
ATOM   1130 H HZ3    . LYS A 1 75  ? -4.772  -33.687 15.233  1    76.851 ? 1083 LYS A HZ3    1 ? 
ATOM   1131 N N      . LYS A 1 76  ? -4.41   -39.464 21.574  1    47.896 ? 1084 LYS A N      1 ? 
ATOM   1132 C CA     . LYS A 1 76  ? -3.667  -40.685 21.842  1    51.805 ? 1084 LYS A CA     1 ? 
ATOM   1133 C C      . LYS A 1 76  ? -3.613  -40.894 23.354  1    59.261 ? 1084 LYS A C      1 ? 
ATOM   1134 O O      . LYS A 1 76  ? -2.64   -40.511 24.012  1    54.558 ? 1084 LYS A O      1 ? 
ATOM   1135 C CB     . LYS A 1 76  ? -2.282  -40.697 21.175  1    55.762 ? 1084 LYS A CB     1 ? 
ATOM   1136 C CG     . LYS A 1 76  ? -2.329  -40.633 19.645  1    63.259 ? 1084 LYS A CG     1 ? 
ATOM   1137 C CD     . LYS A 1 76  ? -1.457  -41.61  18.867  1    64.028 ? 1084 LYS A CD     1 ? 
ATOM   1138 C CE     . LYS A 1 76  ? -2.198  -42.032 17.628  1    63.123 ? 1084 LYS A CE     1 ? 
ATOM   1139 N NZ     . LYS A 1 76  ? -1.491  -43.144 16.996  1    71.797 ? 1084 LYS A NZ     1 ? 
ATOM   1140 H H      . LYS A 1 76  ? -4.614  -38.822 22.358  1    49.148 ? 1084 LYS A H      1 ? 
ATOM   1141 H HA     . LYS A 1 76  ? -4.228  -41.514 21.409  1    53.077 ? 1084 LYS A HA     1 c 
ATOM   1142 H HB2    . LYS A 1 76  ? -1.706  -39.845 21.54   1    56.144 ? 1084 LYS A HB2    1 c 
ATOM   1143 H HB3    . LYS A 1 76  ? -1.754  -41.607 21.469  1    56.36  ? 1084 LYS A HB3    1 c 
ATOM   1144 H HG2    . LYS A 1 76  ? -3.359  -40.8   19.339  1    61.576 ? 1084 LYS A HG2    1 c 
ATOM   1145 H HG3    . LYS A 1 76  ? -2.067  -39.617 19.343  1    61.332 ? 1084 LYS A HG3    1 c 
ATOM   1146 H HD2    . LYS A 1 76  ? -0.515  -41.134 18.588  1    63.464 ? 1084 LYS A HD2    1 c 
ATOM   1147 H HD3    . LYS A 1 76  ? -1.244  -42.487 19.482  1    63.622 ? 1084 LYS A HD3    1 c 
ATOM   1148 H HE2    . LYS A 1 76  ? -3.208  -42.352 17.889  1    65.161 ? 1084 LYS A HE2    1 c 
ATOM   1149 H HE3    . LYS A 1 76  ? -2.263  -41.198 16.927  1    65.183 ? 1084 LYS A HE3    1 c 
ATOM   1150 H HZ1    . LYS A 1 76  ? -2.027  -43.543 16.225  1    66.527 ? 1084 LYS A HZ1    1 ? 
ATOM   1151 H HZ2    . LYS A 1 76  ? -0.588  -42.82  16.657  1    64.384 ? 1084 LYS A HZ2    1 ? 
ATOM   1152 H HZ3    . LYS A 1 76  ? -1.336  -43.872 17.691  1    69.768 ? 1084 LYS A HZ3    1 ? 
ATOM   1153 N N      . PRO A 1 77  ? -4.672  -41.483 23.962  1    57.121 ? 1085 PRO A N      1 ? 
ATOM   1154 C CA     . PRO A 1 77  ? -4.716  -41.619 25.411  1    49.625 ? 1085 PRO A CA     1 ? 
ATOM   1155 C C      . PRO A 1 77  ? -3.527  -42.399 25.964  1    44.71  ? 1085 PRO A C      1 ? 
ATOM   1156 O O      . PRO A 1 77  ? -3.015  -43.328 25.342  1    44.723 ? 1085 PRO A O      1 ? 
ATOM   1157 C CB     . PRO A 1 77  ? -6.088  -42.25  25.682  1    58.375 ? 1085 PRO A CB     1 ? 
ATOM   1158 C CG     . PRO A 1 77  ? -6.554  -42.808 24.343  1    59.317 ? 1085 PRO A CG     1 ? 
ATOM   1159 C CD     . PRO A 1 77  ? -5.885  -41.977 23.287  1    58.88  ? 1085 PRO A CD     1 ? 
ATOM   1160 H HA     . PRO A 1 77  ? -4.709  -40.62  25.852  1    51.383 ? 1085 PRO A HA     1 c 
ATOM   1161 H HB2    . PRO A 1 77  ? -6.006  -43.046 26.425  1    56.571 ? 1085 PRO A HB2    1 c 
ATOM   1162 H HB3    . PRO A 1 77  ? -6.79   -41.501 26.054  1    56.571 ? 1085 PRO A HB3    1 c 
ATOM   1163 H HG2    . PRO A 1 77  ? -6.265  -43.856 24.241  1    59.018 ? 1085 PRO A HG2    1 c 
ATOM   1164 H HG3    . PRO A 1 77  ? -7.64   -42.736 24.253  1    59.018 ? 1085 PRO A HG3    1 c 
ATOM   1165 H HD2    . PRO A 1 77  ? -5.626  -42.581 22.415  1    58.49  ? 1085 PRO A HD2    1 c 
ATOM   1166 H HD3    . PRO A 1 77  ? -6.521  -41.146 22.974  1    58.561 ? 1085 PRO A HD3    1 c 
ATOM   1167 N N      . GLY A 1 78  ? -3.043  -41.939 27.119  1    45.132 ? 1086 GLY A N      1 ? 
ATOM   1168 C CA     . GLY A 1 78  ? -1.989  -42.632 27.848  1    44.138 ? 1086 GLY A CA     1 ? 
ATOM   1169 C C      . GLY A 1 78  ? -0.605  -42.307 27.287  1    44.258 ? 1086 GLY A C      1 ? 
ATOM   1170 O O      . GLY A 1 78  ? 0.401   -42.809 27.788  1    42.069 ? 1086 GLY A O      1 ? 
ATOM   1171 H H      . GLY A 1 78  ? -3.404  -41.04  27.491  1    40.781 ? 1086 GLY A H      1 ? 
ATOM   1172 H HA2    . GLY A 1 78  ? -2.034  -42.342 28.899  1    44.376 ? 1086 GLY A HA2    1 c 
ATOM   1173 H HA3    . GLY A 1 78  ? -2.163  -43.708 27.788  1    44.324 ? 1086 GLY A HA3    1 c 
ATOM   1174 N N      . ALA A 1 79  ? -0.564  -41.452 26.254  1    42.159 ? 1087 ALA A N      1 ? 
ATOM   1175 C CA     . ALA A 1 79  ? 0.665   -41.226 25.515  1    38.41  ? 1087 ALA A CA     1 ? 
ATOM   1176 C C      . ALA A 1 79  ? 1.06    -39.755 25.666  1    36.169 ? 1087 ALA A C      1 ? 
ATOM   1177 O O      . ALA A 1 79  ? 0.213   -38.87  25.814  1    30.786 ? 1087 ALA A O      1 ? 
ATOM   1178 C CB     . ALA A 1 79  ? 0.493   -41.632 24.068  1    33.994 ? 1087 ALA A CB     1 ? 
ATOM   1179 H H      . ALA A 1 79  ? -1.396  -40.885 26      1    36.522 ? 1087 ALA A H      1 ? 
ATOM   1180 H HA     . ALA A 1 79  ? 1.449   -41.838 25.963  1    37.875 ? 1087 ALA A HA     1 c 
ATOM   1181 H HB1    . ALA A 1 79  ? 1.441   -41.515 23.539  1    35.242 ? 1087 ALA A HB1    1 c 
ATOM   1182 H HB2    . ALA A 1 79  ? 0.177   -42.676 24.015  1    35.242 ? 1087 ALA A HB2    1 c 
ATOM   1183 H HB3    . ALA A 1 79  ? -0.263  -41.002 23.597  1    35.456 ? 1087 ALA A HB3    1 c 
ATOM   1184 N N      . PRO A 1 80  ? 2.374   -39.453 25.645  1    35.658 ? 1088 PRO A N      1 ? 
ATOM   1185 C CA     . PRO A 1 80  ? 2.827   -38.076 25.802  1    31.921 ? 1088 PRO A CA     1 ? 
ATOM   1186 C C      . PRO A 1 80  ? 2.406   -37.201 24.627  1    28.008 ? 1088 PRO A C      1 ? 
ATOM   1187 O O      . PRO A 1 80  ? 2.014   -37.675 23.56   1    31.603 ? 1088 PRO A O      1 ? 
ATOM   1188 C CB     . PRO A 1 80  ? 4.322   -38.254 26.065  1    30.567 ? 1088 PRO A CB     1 ? 
ATOM   1189 C CG     . PRO A 1 80  ? 4.636   -39.495 25.245  1    35.217 ? 1088 PRO A CG     1 ? 
ATOM   1190 C CD     . PRO A 1 80  ? 3.48    -40.415 25.513  1    32.644 ? 1088 PRO A CD     1 ? 
ATOM   1191 H HA     . PRO A 1 80  ? 2.376   -37.667 26.709  1    31.595 ? 1088 PRO A HA     1 c 
ATOM   1192 H HB2    . PRO A 1 80  ? 4.891   -37.392 25.713  1    31.808 ? 1088 PRO A HB2    1 c 
ATOM   1193 H HB3    . PRO A 1 80  ? 4.519   -38.42  27.126  1    31.808 ? 1088 PRO A HB3    1 c 
ATOM   1194 H HG2    . PRO A 1 80  ? 4.702   -39.257 24.181  1    33.598 ? 1088 PRO A HG2    1 c 
ATOM   1195 H HG3    . PRO A 1 80  ? 5.573   -39.952 25.566  1    33.586 ? 1088 PRO A HG3    1 c 
ATOM   1196 H HD2    . PRO A 1 80  ? 3.307   -41.101 24.682  1    33.858 ? 1088 PRO A HD2    1 c 
ATOM   1197 H HD3    . PRO A 1 80  ? 3.62    -40.982 26.436  1    33.841 ? 1088 PRO A HD3    1 c 
ATOM   1198 N N      . GLN A 1 81  ? 2.525   -35.899 24.825  1    24.662 ? 1089 GLN A N      1 ? 
ATOM   1199 C CA     . GLN A 1 81  ? 2.328   -34.93  23.756  1    22.906 ? 1089 GLN A CA     1 ? 
ATOM   1200 C C      . GLN A 1 81  ? 3.399   -35.099 22.68   1    22.388 ? 1089 GLN A C      1 ? 
ATOM   1201 O O      . GLN A 1 81  ? 4.509   -35.576 22.93   1    20.901 ? 1089 GLN A O      1 ? 
ATOM   1202 C CB     . GLN A 1 81  ? 2.431   -33.523 24.336  1    22.386 ? 1089 GLN A CB     1 ? 
ATOM   1203 C CG     . GLN A 1 81  ? 1.391   -33.262 25.411  1    21.512 ? 1089 GLN A CG     1 ? 
ATOM   1204 C CD     . GLN A 1 81  ? 0.161   -32.537 24.9    1    20.683 ? 1089 GLN A CD     1 ? 
ATOM   1205 O OE1    . GLN A 1 81  ? -0.281  -32.735 23.761  1    21.972 ? 1089 GLN A OE1    1 ? 
ATOM   1206 N NE2    . GLN A 1 81  ? -0.435  -31.735 25.764  1    20.363 ? 1089 GLN A NE2    1 ? 
ATOM   1207 H H      . GLN A 1 81  ? 2.763   -35.563 25.771  1    25.802 ? 1089 GLN A H      1 ? 
ATOM   1208 H HA     . GLN A 1 81  ? 1.341   -35.087 23.315  1    23.048 ? 1089 GLN A HA     1 c 
ATOM   1209 H HB2    . GLN A 1 81  ? 3.428   -33.385 24.761  1    22.302 ? 1089 GLN A HB2    1 c 
ATOM   1210 H HB3    . GLN A 1 81  ? 2.306   -32.795 23.532  1    22.301 ? 1089 GLN A HB3    1 c 
ATOM   1211 H HG2    . GLN A 1 81  ? 1.076   -34.212 25.844  1    21.56  ? 1089 GLN A HG2    1 c 
ATOM   1212 H HG3    . GLN A 1 81  ? 1.839   -32.668 26.209  1    21.487 ? 1089 GLN A HG3    1 c 
ATOM   1213 H HE21   . GLN A 1 81  ? -0.102  -31.785 26.706  1    19.704 ? 1089 GLN A HE21   1 ? 
ATOM   1214 H HE22   . GLN A 1 81  ? -1.215  -31.134 25.519  1    20.313 ? 1089 GLN A HE22   1 ? 
ATOM   1215 N N      . ASN A 1 82  ? 3.04    -34.709 21.456  1    24.015 ? 1090 ASN A N      1 ? 
ATOM   1216 C CA     . ASN A 1 82  ? 3.993   -34.674 20.36   1    22.208 ? 1090 ASN A CA     1 ? 
ATOM   1217 C C      . ASN A 1 82  ? 5.058   -33.601 20.602  1    21.911 ? 1090 ASN A C      1 ? 
ATOM   1218 O O      . ASN A 1 82  ? 4.804   -32.553 21.199  1    19.652 ? 1090 ASN A O      1 ? 
ATOM   1219 C CB     . ASN A 1 82  ? 3.286   -34.352 19.053  1    23.564 ? 1090 ASN A CB     1 ? 
ATOM   1220 C CG     . ASN A 1 82  ? 2.275   -35.423 18.674  1    25.523 ? 1090 ASN A CG     1 ? 
ATOM   1221 O OD1    . ASN A 1 82  ? 2.481   -36.613 18.913  1    29.188 ? 1090 ASN A OD1    1 ? 
ATOM   1222 N ND2    . ASN A 1 82  ? 1.166   -35.041 18.071  1    27.381 ? 1090 ASN A ND2    1 ? 
ATOM   1223 H H      . ASN A 1 82  ? 2.058   -34.421 21.3    1    23.288 ? 1090 ASN A H      1 ? 
ATOM   1224 H HA     . ASN A 1 82  ? 4.468   -35.652 20.265  1    22.755 ? 1090 ASN A HA     1 c 
ATOM   1225 H HB2    . ASN A 1 82  ? 2.773   -33.392 19.148  1    23.729 ? 1090 ASN A HB2    1 c 
ATOM   1226 H HB3    . ASN A 1 82  ? 4.028   -34.261 18.257  1    23.764 ? 1090 ASN A HB3    1 c 
ATOM   1227 H HD21   . ASN A 1 82  ? 0.465   -35.734 17.847  1    26.409 ? 1090 ASN A HD21   1 ? 
ATOM   1228 H HD22   . ASN A 1 82  ? 1.04    -34.046 17.82   1    26.235 ? 1090 ASN A HD22   1 ? 
ATOM   1229 N N      . VAL A 1 83  ? 6.265   -33.883 20.117  1    20.52  ? 1091 VAL A N      1 ? 
ATOM   1230 C CA     . VAL A 1 83  ? 7.334   -32.9   20.099  1    21.21  ? 1091 VAL A CA     1 ? 
ATOM   1231 C C      . VAL A 1 83  ? 6.931   -31.69  19.269  1    19.683 ? 1091 VAL A C      1 ? 
ATOM   1232 O O      . VAL A 1 83  ? 6.362   -31.829 18.182  1    21.69  ? 1091 VAL A O      1 ? 
ATOM   1233 C CB     . VAL A 1 83  ? 8.58    -33.556 19.483  1    21.085 ? 1091 VAL A CB     1 ? 
ATOM   1234 C CG1    . VAL A 1 83  ? 9.657   -32.525 19.161  1    20.27  ? 1091 VAL A CG1    1 ? 
ATOM   1235 C CG2    . VAL A 1 83  ? 9.138   -34.651 20.372  1    21.872 ? 1091 VAL A CG2    1 ? 
ATOM   1236 H H      . VAL A 1 83  ? 6.436   -34.811 19.7    1    19.89  ? 1091 VAL A H      1 ? 
ATOM   1237 H HA     . VAL A 1 83  ? 7.555   -32.587 21.121  1    20.78  ? 1091 VAL A HA     1 c 
ATOM   1238 H HB     . VAL A 1 83  ? 8.269   -34.017 18.543  1    21.098 ? 1091 VAL A HB     1 c 
ATOM   1239 H HG11   . VAL A 1 83  ? 9.854   -31.915 20.046  1    20.496 ? 1091 VAL A HG11   1 c 
ATOM   1240 H HG12   . VAL A 1 83  ? 10.575  -33.037 18.864  1    20.496 ? 1091 VAL A HG12   1 c 
ATOM   1241 H HG13   . VAL A 1 83  ? 9.32    -31.882 18.346  1    20.506 ? 1091 VAL A HG13   1 c 
ATOM   1242 H HG21   . VAL A 1 83  ? 8.371   -35.411 20.541  1    21.635 ? 1091 VAL A HG21   1 c 
ATOM   1243 H HG22   . VAL A 1 83  ? 10.003  -35.109 19.888  1    21.64  ? 1091 VAL A HG22   1 c 
ATOM   1244 H HG23   . VAL A 1 83  ? 9.442   -34.224 21.33   1    21.616 ? 1091 VAL A HG23   1 c 
ATOM   1245 N N      . ARG A 1 84  ? 7.261   -30.491 19.757  1    18.136 ? 1092 ARG A N      1 ? 
ATOM   1246 C CA     . ARG A 1 84  ? 7.301   -29.287 18.943  1    17.226 ? 1092 ARG A CA     1 ? 
ATOM   1247 C C      . ARG A 1 84  ? 8.752   -28.853 18.774  1    18.167 ? 1092 ARG A C      1 ? 
ATOM   1248 O O      . ARG A 1 84  ? 9.53    -28.864 19.734  1    14.323 ? 1092 ARG A O      1 ? 
ATOM   1249 C CB     . ARG A 1 84  ? 6.502   -28.144 19.576  1    19.392 ? 1092 ARG A CB     1 ? 
ATOM   1250 C CG     . ARG A 1 84  ? 4.988   -28.212 19.394  1    18.14  ? 1092 ARG A CG     1 ? 
ATOM   1251 C CD     . ARG A 1 84  ? 4.328   -29.306 20.208  1    18.401 ? 1092 ARG A CD     1 ? 
ATOM   1252 N NE     . ARG A 1 84  ? 2.913   -28.986 20.41   1    19.904 ? 1092 ARG A NE     1 ? 
ATOM   1253 C CZ     . ARG A 1 84  ? 1.99    -29.85  20.774  1    20.97  ? 1092 ARG A CZ     1 ? 
ATOM   1254 N NH1    . ARG A 1 84  ? 2.283   -31.107 21.067  1    22.886 ? 1092 ARG A NH1    1 ? 
ATOM   1255 N NH2    . ARG A 1 84  ? 0.728   -29.463 20.878  1    20.965 ? 1092 ARG A NH2    1 ? 
ATOM   1256 H H      . ARG A 1 84  ? 7.51    -30.393 20.753  1    20.127 ? 1092 ARG A H      1 ? 
ATOM   1257 H HA     . ARG A 1 84  ? 6.884   -29.516 17.96   1    17.962 ? 1092 ARG A HA     1 c 
ATOM   1258 H HB2    . ARG A 1 84  ? 6.72    -28.124 20.646  1    18.623 ? 1092 ARG A HB2    1 c 
ATOM   1259 H HB3    . ARG A 1 84  ? 6.858   -27.202 19.153  1    18.623 ? 1092 ARG A HB3    1 c 
ATOM   1260 H HG2    . ARG A 1 84  ? 4.552   -27.252 19.677  1    18.425 ? 1092 ARG A HG2    1 c 
ATOM   1261 H HG3    . ARG A 1 84  ? 4.764   -28.376 18.337  1    18.455 ? 1092 ARG A HG3    1 c 
ATOM   1262 H HD2    . ARG A 1 84  ? 4.415   -30.26  19.683  1    18.695 ? 1092 ARG A HD2    1 c 
ATOM   1263 H HD3    . ARG A 1 84  ? 4.823   -29.399 21.176  1    18.677 ? 1092 ARG A HD3    1 c 
ATOM   1264 H HE     . ARG A 1 84  ? 2.579   -27.983 20.384  1    16.409 ? 1092 ARG A HE     1 ? 
ATOM   1265 H HH11   . ARG A 1 84  ? 3.229   -31.467 20.977  1    21.681 ? 1092 ARG A HH11   1 ? 
ATOM   1266 H HH12   . ARG A 1 84  ? 1.533   -31.759 21.25   1    23.245 ? 1092 ARG A HH12   1 ? 
ATOM   1267 H HH21   . ARG A 1 84  ? 0.378   -28.549 20.583  1    19.063 ? 1092 ARG A HH21   1 ? 
ATOM   1268 H HH22   . ARG A 1 84  ? 0.076   -30.132 21.233  1    19.647 ? 1092 ARG A HH22   1 ? 
ATOM   1269 N N      . LEU A 1 85  ? 9.112   -28.464 17.552  1    16.914 ? 1093 LEU A N      1 ? 
ATOM   1270 C CA     . LEU A 1 85  ? 10.473  -28.068 17.221  1    15.792 ? 1093 LEU A CA     1 ? 
ATOM   1271 C C      . LEU A 1 85  ? 10.644  -26.558 17.296  1    16.011 ? 1093 LEU A C      1 ? 
ATOM   1272 O O      . LEU A 1 85  ? 9.767   -25.799 16.88   1    16.213 ? 1093 LEU A O      1 ? 
ATOM   1273 C CB     . LEU A 1 85  ? 10.849  -28.572 15.828  1    14.866 ? 1093 LEU A CB     1 ? 
ATOM   1274 C CG     . LEU A 1 85  ? 10.973  -30.095 15.685  1    16.568 ? 1093 LEU A CG     1 ? 
ATOM   1275 C CD1    . LEU A 1 85  ? 11.3    -30.48  14.261  1    16.559 ? 1093 LEU A CD1    1 ? 
ATOM   1276 C CD2    . LEU A 1 85  ? 12.138  -30.639 16.454  1    16.86  ? 1093 LEU A CD2    1 ? 
ATOM   1277 H H      . LEU A 1 85  ? 8.372   -28.435 16.831  1    18.196 ? 1093 LEU A H      1 ? 
ATOM   1278 H HA     . LEU A 1 85  ? 11.143  -28.523 17.952  1    15.869 ? 1093 LEU A HA     1 c 
ATOM   1279 H HB2    . LEU A 1 85  ? 10.094  -28.219 15.123  1    15.423 ? 1093 LEU A HB2    1 c 
ATOM   1280 H HB3    . LEU A 1 85  ? 11.803  -28.12  15.548  1    15.423 ? 1093 LEU A HB3    1 c 
ATOM   1281 H HG     . LEU A 1 85  ? 10.049  -30.575 16.007  1    16.392 ? 1093 LEU A HG     1 c 
ATOM   1282 H HD11   . LEU A 1 85  ? 11.375  -31.566 14.184  1    16.55  ? 1093 LEU A HD11   1 c 
ATOM   1283 H HD12   . LEU A 1 85  ? 10.51   -30.124 13.596  1    16.549 ? 1093 LEU A HD12   1 c 
ATOM   1284 H HD13   . LEU A 1 85  ? 12.25   -30.029 13.969  1    16.512 ? 1093 LEU A HD13   1 c 
ATOM   1285 H HD21   . LEU A 1 85  ? 12.006  -30.426 17.517  1    16.756 ? 1093 LEU A HD21   1 c 
ATOM   1286 H HD22   . LEU A 1 85  ? 12.201  -31.719 16.306  1    16.762 ? 1093 LEU A HD22   1 c 
ATOM   1287 H HD23   . LEU A 1 85  ? 13.059  -30.171 16.101  1    16.719 ? 1093 LEU A HD23   1 c 
ATOM   1288 N N      . TYR A 1 86  ? 11.81   -26.121 17.785  1    16.402 ? 1094 TYR A N      1 ? 
ATOM   1289 C CA     . TYR A 1 86  ? 12.132  -24.7   17.867  1    15.509 ? 1094 TYR A CA     1 ? 
ATOM   1290 C C      . TYR A 1 86  ? 13.559  -24.492 17.383  1    16.736 ? 1094 TYR A C      1 ? 
ATOM   1291 O O      . TYR A 1 86  ? 14.49   -25.108 17.911  1    15.01  ? 1094 TYR A O      1 ? 
ATOM   1292 C CB     . TYR A 1 86  ? 11.961  -24.169 19.305  1    14.63  ? 1094 TYR A CB     1 ? 
ATOM   1293 C CG     . TYR A 1 86  ? 10.513  -24.23  19.714  1    14.917 ? 1094 TYR A CG     1 ? 
ATOM   1294 C CD1    . TYR A 1 86  ? 9.641   -23.218 19.353  1    14.715 ? 1094 TYR A CD1    1 ? 
ATOM   1295 C CD2    . TYR A 1 86  ? 9.991   -25.347 20.365  1    15.197 ? 1094 TYR A CD2    1 ? 
ATOM   1296 C CE1    . TYR A 1 86  ? 8.282   -23.296 19.633  1    15.423 ? 1094 TYR A CE1    1 ? 
ATOM   1297 C CE2    . TYR A 1 86  ? 8.635   -25.44  20.656  1    15.415 ? 1094 TYR A CE2    1 ? 
ATOM   1298 C CZ     . TYR A 1 86  ? 7.78    -24.407 20.285  1    17.201 ? 1094 TYR A CZ     1 ? 
ATOM   1299 O OH     . TYR A 1 86  ? 6.426   -24.483 20.541  1    18.157 ? 1094 TYR A OH     1 ? 
ATOM   1300 H H      . TYR A 1 86  ? 12.494  -26.826 18.119  1    16.13  ? 1094 TYR A H      1 ? 
ATOM   1301 H HA     . TYR A 1 86  ? 11.457  -24.15  17.21   1    15.735 ? 1094 TYR A HA     1 c 
ATOM   1302 H HB2    . TYR A 1 86  ? 12.559  -24.778 19.985  1    14.878 ? 1094 TYR A HB2    1 c 
ATOM   1303 H HB3    . TYR A 1 86  ? 12.309  -23.135 19.348  1    14.878 ? 1094 TYR A HB3    1 c 
ATOM   1304 H HD1    . TYR A 1 86  ? 10.022  -22.355 18.817  1    14.934 ? 1094 TYR A HD1    1 c 
ATOM   1305 H HD2    . TYR A 1 86  ? 10.65   -26.166 20.632  1    15.196 ? 1094 TYR A HD2    1 c 
ATOM   1306 H HE1    . TYR A 1 86  ? 7.618   -22.489 19.342  1    15.624 ? 1094 TYR A HE1    1 c 
ATOM   1307 H HE2    . TYR A 1 86  ? 8.243   -26.314 21.165  1    15.737 ? 1094 TYR A HE2    1 c 
ATOM   1308 H HH     . TYR A 1 86  ? 5.952   -23.955 19.875  1    18.32  ? 1094 TYR A HH     1 ? 
ATOM   1309 N N      . SER A 1 87  ? 13.738  -23.609 16.397  1    16.054 ? 1095 SER A N      1 ? 
ATOM   1310 C CA     . SER A 1 87  ? 15.077  -23.233 15.958  1    15.859 ? 1095 SER A CA     1 ? 
ATOM   1311 C C      . SER A 1 87  ? 15.868  -22.68  17.131  1    14.538 ? 1095 SER A C      1 ? 
ATOM   1312 O O      . SER A 1 87  ? 15.414  -21.77  17.825  1    15.189 ? 1095 SER A O      1 ? 
ATOM   1313 C CB     . SER A 1 87  ? 14.981  -22.119 14.936  1    15.406 ? 1095 SER A CB     1 ? 
ATOM   1314 O OG     . SER A 1 87  ? 14.294  -22.514 13.77   1    17.229 ? 1095 SER A OG     1 ? 
ATOM   1315 H H      . SER A 1 87  ? 12.917  -23.179 15.923  1    16.31  ? 1095 SER A H      1 ? 
ATOM   1316 H HA     . SER A 1 87  ? 15.59   -24.097 15.532  1    15.573 ? 1095 SER A HA     1 c 
ATOM   1317 H HB2    . SER A 1 87  ? 14.466  -21.267 15.385  1    15.895 ? 1095 SER A HB2    1 c 
ATOM   1318 H HB3    . SER A 1 87  ? 15.988  -21.795 14.666  1    15.909 ? 1095 SER A HB3    1 c 
ATOM   1319 H HG     . SER A 1 87  ? 15.001  -22.764 13.137  1    17.153 ? 1095 SER A HG     1 ? 
ATOM   1320 N N      . ILE A 1 88  ? 17.079  -23.188 17.336  1    16.088 ? 1096 ILE A N      1 ? 
ATOM   1321 C CA     . ILE A 1 88  ? 17.884  -22.674 18.428  1    14.56  ? 1096 ILE A CA     1 ? 
ATOM   1322 C C      . ILE A 1 88  ? 18.378  -21.274 18.065  1    13.794 ? 1096 ILE A C      1 ? 
ATOM   1323 O O      . ILE A 1 88  ? 18.87   -21.037 16.955  1    13.996 ? 1096 ILE A O      1 ? 
ATOM   1324 C CB     . ILE A 1 88  ? 19.005  -23.667 18.759  1    16.061 ? 1096 ILE A CB     1 ? 
ATOM   1325 C CG1    . ILE A 1 88  ? 18.395  -25.003 19.228  1    15.333 ? 1096 ILE A CG1    1 ? 
ATOM   1326 C CG2    . ILE A 1 88  ? 19.929  -23.099 19.812  1    15.507 ? 1096 ILE A CG2    1 ? 
ATOM   1327 C CD1    . ILE A 1 88  ? 19.357  -26.198 19.179  1    14.408 ? 1096 ILE A CD1    1 ? 
ATOM   1328 H H      . ILE A 1 88  ? 17.405  -24.003 16.784  1    14.792 ? 1096 ILE A H      1 ? 
ATOM   1329 H HA     . ILE A 1 88  ? 17.242  -22.59  19.307  1    14.939 ? 1096 ILE A HA     1 c 
ATOM   1330 H HB     . ILE A 1 88  ? 19.583  -23.851 17.851  1    15.553 ? 1096 ILE A HB     1 c 
ATOM   1331 H HG12   . ILE A 1 88  ? 18.041  -24.883 20.254  1    15.28  ? 1096 ILE A HG12   1 c 
ATOM   1332 H HG13   . ILE A 1 88  ? 17.528  -25.23  18.604  1    15.284 ? 1096 ILE A HG13   1 c 
ATOM   1333 H HG21   . ILE A 1 88  ? 20.565  -23.894 20.203  1    15.603 ? 1096 ILE A HG21   1 c 
ATOM   1334 H HG22   . ILE A 1 88  ? 20.554  -22.32  19.372  1    15.611 ? 1096 ILE A HG22   1 c 
ATOM   1335 H HG23   . ILE A 1 88  ? 19.339  -22.676 20.628  1    15.609 ? 1096 ILE A HG23   1 c 
ATOM   1336 H HD11   . ILE A 1 88  ? 18.834  -27.104 19.493  1    14.664 ? 1096 ILE A HD11   1 c 
ATOM   1337 H HD12   . ILE A 1 88  ? 19.728  -26.33  18.16   1    14.664 ? 1096 ILE A HD12   1 c 
ATOM   1338 H HD13   . ILE A 1 88  ? 20.198  -26.014 19.85   1    14.688 ? 1096 ILE A HD13   1 c 
ATOM   1339 N N      . ALA A 1 89  ? 18.226  -20.329 19.001  1    13.464 ? 1097 ALA A N      1 ? 
ATOM   1340 C CA     . ALA A 1 89  ? 18.533  -18.923 18.771  1    12.753 ? 1097 ALA A CA     1 ? 
ATOM   1341 C C      . ALA A 1 89  ? 19.89   -18.54  19.34   1    13.412 ? 1097 ALA A C      1 ? 
ATOM   1342 O O      . ALA A 1 89  ? 20.279  -17.373 19.261  1    11.711 ? 1097 ALA A O      1 ? 
ATOM   1343 C CB     . ALA A 1 89  ? 17.441  -18.027 19.367  1    13.684 ? 1097 ALA A CB     1 ? 
ATOM   1344 H H      . ALA A 1 89  ? 17.764  -20.591 19.891  1    13.065 ? 1097 ALA A H      1 ? 
ATOM   1345 H HA     . ALA A 1 89  ? 18.566  -18.761 17.695  1    13.17  ? 1097 ALA A HA     1 c 
ATOM   1346 H HB1    . ALA A 1 89  ? 17.371  -18.201 20.443  1    13.421 ? 1097 ALA A HB1    1 c 
ATOM   1347 H HB2    . ALA A 1 89  ? 17.687  -16.979 19.187  1    13.421 ? 1097 ALA A HB2    1 c 
ATOM   1348 H HB3    . ALA A 1 89  ? 16.481  -18.258 18.901  1    13.422 ? 1097 ALA A HB3    1 c 
ATOM   1349 N N      . SER A 1 90  ? 20.61   -19.496 19.915  1    13.098 ? 1098 SER A N      1 ? 
ATOM   1350 C CA     . SER A 1 90  ? 21.911  -19.295 20.523  1    13.271 ? 1098 SER A CA     1 ? 
ATOM   1351 C C      . SER A 1 90  ? 23.008  -19.99  19.711  1    13.03  ? 1098 SER A C      1 ? 
ATOM   1352 O O      . SER A 1 90  ? 22.753  -20.863 18.881  1    11.936 ? 1098 SER A O      1 ? 
ATOM   1353 C CB     . SER A 1 90  ? 21.872  -19.859 21.945  1    11.902 ? 1098 SER A CB     1 ? 
ATOM   1354 O OG     . SER A 1 90  ? 21.249  -21.135 21.949  1    13.365 ? 1098 SER A OG     1 ? 
ATOM   1355 H H      . SER A 1 90  ? 20.162  -20.416 20.052  1    13.571 ? 1098 SER A H      1 ? 
ATOM   1356 H HA     . SER A 1 90  ? 22.123  -18.226 20.566  1    12.947 ? 1098 SER A HA     1 c 
ATOM   1357 H HB2    . SER A 1 90  ? 22.889  -19.948 22.328  1    12.547 ? 1098 SER A HB2    1 c 
ATOM   1358 H HB3    . SER A 1 90  ? 21.316  -19.178 22.593  1    12.519 ? 1098 SER A HB3    1 c 
ATOM   1359 H HG     . SER A 1 90  ? 21.824  -21.912 21.882  1    13.8   ? 1098 SER A HG     1 ? 
ATOM   1360 N N      . THR A 1 91  ? 24.25   -19.591 19.962  1    12.373 ? 1099 THR A N      1 ? 
ATOM   1361 C CA     . THR A 1 91  ? 25.377  -20.361 19.457  1    12.084 ? 1099 THR A CA     1 ? 
ATOM   1362 C C      . THR A 1 91  ? 25.537  -21.634 20.283  1    12.648 ? 1099 THR A C      1 ? 
ATOM   1363 O O      . THR A 1 91  ? 24.93   -21.794 21.347  1    13.348 ? 1099 THR A O      1 ? 
ATOM   1364 C CB     . THR A 1 91  ? 26.684  -19.589 19.612  1    12.003 ? 1099 THR A CB     1 ? 
ATOM   1365 O OG1    . THR A 1 91  ? 27.042  -19.602 21.001  1    11.119 ? 1099 THR A OG1    1 ? 
ATOM   1366 C CG2    . THR A 1 91  ? 26.548  -18.164 19.085  1    11.281 ? 1099 THR A CG2    1 ? 
ATOM   1367 H H      . THR A 1 91  ? 24.363  -18.94  20.768  1    12.462 ? 1099 THR A H      1 ? 
ATOM   1368 H HA     . THR A 1 91  ? 25.214  -20.611 18.409  1    12.242 ? 1099 THR A HA     1 c 
ATOM   1369 H HB     . THR A 1 91  ? 27.464  -20.095 19.04   1    11.742 ? 1099 THR A HB     1 c 
ATOM   1370 H HG1    . THR A 1 91  ? 27.678  -18.92  21.212  1    11.089 ? 1099 THR A HG1    1 ? 
ATOM   1371 H HG21   . THR A 1 91  ? 27.524  -17.678 19.082  1    11.519 ? 1099 THR A HG21   1 c 
ATOM   1372 H HG22   . THR A 1 91  ? 26.155  -18.19  18.067  1    11.519 ? 1099 THR A HG22   1 c 
ATOM   1373 H HG23   . THR A 1 91  ? 25.863  -17.602 19.723  1    11.511 ? 1099 THR A HG23   1 c 
ATOM   1374 N N      . ARG A 1 92  ? 26.43   -22.512 19.829  1    12.995 ? 1100 ARG A N      1 ? 
ATOM   1375 C CA     . ARG A 1 92  ? 26.73   -23.726 20.583  1    14.057 ? 1100 ARG A CA     1 ? 
ATOM   1376 C C      . ARG A 1 92  ? 27.243  -23.429 21.994  1    15.237 ? 1100 ARG A C      1 ? 
ATOM   1377 O O      . ARG A 1 92  ? 27.131  -24.295 22.863  1    16.535 ? 1100 ARG A O      1 ? 
ATOM   1378 C CB     . ARG A 1 92  ? 27.75   -24.592 19.831  1    13.944 ? 1100 ARG A CB     1 ? 
ATOM   1379 C CG     . ARG A 1 92  ? 29.145  -23.985 19.75   1    14.506 ? 1100 ARG A CG     1 ? 
ATOM   1380 C CD     . ARG A 1 92  ? 30.049  -24.836 18.874  1    13.762 ? 1100 ARG A CD     1 ? 
ATOM   1381 N NE     . ARG A 1 92  ? 29.614  -24.748 17.478  1    15.401 ? 1100 ARG A NE     1 ? 
ATOM   1382 C CZ     . ARG A 1 92  ? 30.07   -25.521 16.507  1    16.489 ? 1100 ARG A CZ     1 ? 
ATOM   1383 N NH1    . ARG A 1 92  ? 30.924  -26.499 16.75   1    18.808 ? 1100 ARG A NH1    1 ? 
ATOM   1384 N NH2    . ARG A 1 92  ? 29.668  -25.293 15.265  1    18.78  ? 1100 ARG A NH2    1 ? 
ATOM   1385 H H      . ARG A 1 92  ? 26.917  -22.351 18.93   1    13.173 ? 1100 ARG A H      1 ? 
ATOM   1386 H HA     . ARG A 1 92  ? 25.807  -24.3   20.674  1    14.021 ? 1100 ARG A HA     1 c 
ATOM   1387 H HB2    . ARG A 1 92  ? 27.818  -25.56  20.33   1    14.09  ? 1100 ARG A HB2    1 c 
ATOM   1388 H HB3    . ARG A 1 92  ? 27.382  -24.767 18.818  1    14.096 ? 1100 ARG A HB3    1 c 
ATOM   1389 H HG2    . ARG A 1 92  ? 29.081  -22.978 19.331  1    14.219 ? 1100 ARG A HG2    1 c 
ATOM   1390 H HG3    . ARG A 1 92  ? 29.576  -23.918 20.751  1    14.223 ? 1100 ARG A HG3    1 c 
ATOM   1391 H HD2    . ARG A 1 92  ? 31.081  -24.487 18.956  1    14.302 ? 1100 ARG A HD2    1 c 
ATOM   1392 H HD3    . ARG A 1 92  ? 30.011  -25.877 19.202  1    14.282 ? 1100 ARG A HD3    1 c 
ATOM   1393 H HE     . ARG A 1 92  ? 29.062  -23.952 17.175  1    14.869 ? 1100 ARG A HE     1 ? 
ATOM   1394 H HH11   . ARG A 1 92  ? 31.395  -26.578 17.647  1    18.988 ? 1100 ARG A HH11   1 ? 
ATOM   1395 H HH12   . ARG A 1 92  ? 31.152  -27.091 15.954  1    19.896 ? 1100 ARG A HH12   1 ? 
ATOM   1396 H HH21   . ARG A 1 92  ? 29.035  -24.489 15.155  1    19.255 ? 1100 ARG A HH21   1 ? 
ATOM   1397 H HH22   . ARG A 1 92  ? 29.961  -25.885 14.505  1    18.582 ? 1100 ARG A HH22   1 ? 
ATOM   1398 N N      . TYR A 1 93  ? 27.815  -22.242 22.231  1    14.539 ? 1101 TYR A N      1 ? 
ATOM   1399 C CA     . TYR A 1 93  ? 28.262  -21.859 23.566  1    12.673 ? 1101 TYR A CA     1 ? 
ATOM   1400 C C      . TYR A 1 93  ? 27.132  -21.303 24.417  1    14.03  ? 1101 TYR A C      1 ? 
ATOM   1401 O O      . TYR A 1 93  ? 27.211  -21.344 25.653  1    13.519 ? 1101 TYR A O      1 ? 
ATOM   1402 C CB     . TYR A 1 93  ? 29.427  -20.856 23.479  1    12.453 ? 1101 TYR A CB     1 ? 
ATOM   1403 C CG     . TYR A 1 93  ? 30.586  -21.485 22.735  1    13.511 ? 1101 TYR A CG     1 ? 
ATOM   1404 C CD1    . TYR A 1 93  ? 31.409  -22.407 23.373  1    14.147 ? 1101 TYR A CD1    1 ? 
ATOM   1405 C CD2    . TYR A 1 93  ? 30.795  -21.236 21.379  1    13.257 ? 1101 TYR A CD2    1 ? 
ATOM   1406 C CE1    . TYR A 1 93  ? 32.423  -23.051 22.696  1    15.056 ? 1101 TYR A CE1    1 ? 
ATOM   1407 C CE2    . TYR A 1 93  ? 31.814  -21.878 20.683  1    15.135 ? 1101 TYR A CE2    1 ? 
ATOM   1408 C CZ     . TYR A 1 93  ? 32.624  -22.789 21.348  1    17.264 ? 1101 TYR A CZ     1 ? 
ATOM   1409 O OH     . TYR A 1 93  ? 33.63   -23.458 20.697  1    19.46  ? 1101 TYR A OH     1 ? 
ATOM   1410 H H      . TYR A 1 93  ? 27.983  -21.59  21.444  1    14.15  ? 1101 TYR A H      1 ? 
ATOM   1411 H HA     . TYR A 1 93  ? 28.637  -22.758 24.059  1    13.222 ? 1101 TYR A HA     1 c 
ATOM   1412 H HB2    . TYR A 1 93  ? 29.093  -19.962 22.95   1    12.725 ? 1101 TYR A HB2    1 c 
ATOM   1413 H HB3    . TYR A 1 93  ? 29.744  -20.584 24.488  1    12.725 ? 1101 TYR A HB3    1 c 
ATOM   1414 H HD1    . TYR A 1 93  ? 31.243  -22.634 24.42   1    14.227 ? 1101 TYR A HD1    1 c 
ATOM   1415 H HD2    . TYR A 1 93  ? 30.148  -20.541 20.856  1    13.744 ? 1101 TYR A HD2    1 c 
ATOM   1416 H HE1    . TYR A 1 93  ? 33.056  -23.762 23.212  1    15.299 ? 1101 TYR A HE1    1 c 
ATOM   1417 H HE2    . TYR A 1 93  ? 31.973  -21.674 19.629  1    15.13  ? 1101 TYR A HE2    1 c 
ATOM   1418 H HH     . TYR A 1 93  ? 33.522  -23.359 19.719  1    18.69  ? 1101 TYR A HH     1 ? 
ATOM   1419 N N      . GLY A 1 94  ? 26.096  -20.777 23.784  1    14.475 ? 1102 GLY A N      1 ? 
ATOM   1420 C CA     . GLY A 1 94  ? 24.948  -20.263 24.494  1    14.878 ? 1102 GLY A CA     1 ? 
ATOM   1421 C C      . GLY A 1 94  ? 25.188  -18.879 25.072  1    16.214 ? 1102 GLY A C      1 ? 
ATOM   1422 O O      . GLY A 1 94  ? 26.282  -18.321 25.03   1    16.895 ? 1102 GLY A O      1 ? 
ATOM   1423 H H      . GLY A 1 94  ? 26.093  -20.802 22.751  1    14.264 ? 1102 GLY A H      1 ? 
ATOM   1424 H HA2    . GLY A 1 94  ? 24.1    -20.226 23.811  1    15.051 ? 1102 GLY A HA2    1 c 
ATOM   1425 H HA3    . GLY A 1 94  ? 24.693  -20.951 25.3    1    15.143 ? 1102 GLY A HA3    1 c 
ATOM   1426 N N      . ASP A 1 95  ? 24.115  -18.326 25.638  1    15.268 ? 1103 ASP A N      1 ? 
ATOM   1427 C CA     . ASP A 1 95  ? 24.087  -16.945 26.076  1    17.799 ? 1103 ASP A CA     1 ? 
ATOM   1428 C C      . ASP A 1 95  ? 24.962  -16.688 27.301  1    16.811 ? 1103 ASP A C      1 ? 
ATOM   1429 O O      . ASP A 1 95  ? 25.264  -15.53  27.6    1    15.803 ? 1103 ASP A O      1 ? 
ATOM   1430 C CB     . ASP A 1 95  ? 22.647  -16.553 26.357  1    17.643 ? 1103 ASP A CB     1 ? 
ATOM   1431 C CG     . ASP A 1 95  ? 21.776  -16.441 25.129  1    17.677 ? 1103 ASP A CG     1 ? 
ATOM   1432 O OD1    . ASP A 1 95  ? 22.272  -16.579 23.989  1    19.009 ? 1103 ASP A OD1    1 ? 
ATOM   1433 O OD2    . ASP A 1 95  ? 20.546  -16.296 25.321  1    19.641 ? 1103 ASP A OD2    1 ? 
ATOM   1434 H H      . ASP A 1 95  ? 23.213  -18.821 25.551  1    16.206 ? 1103 ASP A H      1 ? 
ATOM   1435 H HA     . ASP A 1 95  ? 24.45   -16.321 25.257  1    17.099 ? 1103 ASP A HA     1 c 
ATOM   1436 H HB2    . ASP A 1 95  ? 22.205  -17.296 27.024  1    17.694 ? 1103 ASP A HB2    1 c 
ATOM   1437 H HB3    . ASP A 1 95  ? 22.639  -15.59  26.872  1    17.732 ? 1103 ASP A HB3    1 c 
ATOM   1438 N N      . ASN A 1 96  ? 25.383  -17.744 27.997  1    16.428 ? 1104 ASN A N      1 ? 
ATOM   1439 C CA     . ASN A 1 96  ? 26.295  -17.63  29.138  1    17.289 ? 1104 ASN A CA     1 ? 
ATOM   1440 C C      . ASN A 1 96  ? 27.735  -17.996 28.726  1    16.192 ? 1104 ASN A C      1 ? 
ATOM   1441 O O      . ASN A 1 96  ? 28.609  -18.063 29.592  1    15.559 ? 1104 ASN A O      1 ? 
ATOM   1442 C CB     . ASN A 1 96  ? 25.707  -18.402 30.321  1    19.65  ? 1104 ASN A CB     1 ? 
ATOM   1443 C CG     . ASN A 1 96  ? 26.236  -17.987 31.691  1    22.675 ? 1104 ASN A CG     1 ? 
ATOM   1444 O OD1    . ASN A 1 96  ? 26.393  -16.79  31.954  1    21.842 ? 1104 ASN A OD1    1 ? 
ATOM   1445 N ND2    . ASN A 1 96  ? 26.514  -18.946 32.585  1    25.906 ? 1104 ASN A ND2    1 ? 
ATOM   1446 H H      . ASN A 1 96  ? 25.107  -18.705 27.692  1    14.811 ? 1104 ASN A H      1 ? 
ATOM   1447 H HA     . ASN A 1 96  ? 26.31   -16.58  29.434  1    17.33  ? 1104 ASN A HA     1 c 
ATOM   1448 H HB2    . ASN A 1 96  ? 24.625  -18.272 30.31   1    19.875 ? 1104 ASN A HB2    1 c 
ATOM   1449 H HB3    . ASN A 1 96  ? 25.911  -19.465 30.178  1    19.748 ? 1104 ASN A HB3    1 c 
ATOM   1450 H HD21   . ASN A 1 96  ? 26.649  -18.718 33.578  1    24.004 ? 1104 ASN A HD21   1 ? 
ATOM   1451 H HD22   . ASN A 1 96  ? 26.536  -19.943 32.319  1    22.602 ? 1104 ASN A HD22   1 ? 
ATOM   1452 N N      . PHE A 1 97  ? 27.976  -18.251 27.438  1    13.432 ? 1105 PHE A N      1 ? 
ATOM   1453 C CA     . PHE A 1 97  ? 29.324  -18.425 26.907  1    13.749 ? 1105 PHE A CA     1 ? 
ATOM   1454 C C      . PHE A 1 97  ? 30.062  -19.615 27.517  1    13.552 ? 1105 PHE A C      1 ? 
ATOM   1455 O O      . PHE A 1 97  ? 31.294  -19.634 27.558  1    14.727 ? 1105 PHE A O      1 ? 
ATOM   1456 C CB     . PHE A 1 97  ? 30.145  -17.137 27.022  1    14.358 ? 1105 PHE A CB     1 ? 
ATOM   1457 C CG     . PHE A 1 97  ? 29.441  -15.916 26.469  1    15.45  ? 1105 PHE A CG     1 ? 
ATOM   1458 C CD1    . PHE A 1 97  ? 29.259  -15.764 25.094  1    16.88  ? 1105 PHE A CD1    1 ? 
ATOM   1459 C CD2    . PHE A 1 97  ? 28.972  -14.925 27.314  1    15.303 ? 1105 PHE A CD2    1 ? 
ATOM   1460 C CE1    . PHE A 1 97  ? 28.614  -14.635 24.589  1    18.205 ? 1105 PHE A CE1    1 ? 
ATOM   1461 C CE2    . PHE A 1 97  ? 28.32   -13.802 26.804  1    16.753 ? 1105 PHE A CE2    1 ? 
ATOM   1462 C CZ     . PHE A 1 97  ? 28.15   -13.657 25.44   1    17.985 ? 1105 PHE A CZ     1 ? 
ATOM   1463 H H      . PHE A 1 97  ? 27.194  -18.247 26.754  1    14.339 ? 1105 PHE A H      1 ? 
ATOM   1464 H HA     . PHE A 1 97  ? 29.214  -18.635 25.841  1    13.759 ? 1105 PHE A HA     1 c 
ATOM   1465 H HB2    . PHE A 1 97  ? 30.378  -16.965 28.074  1    14.461 ? 1105 PHE A HB2    1 c 
ATOM   1466 H HB3    . PHE A 1 97  ? 31.086  -17.276 26.486  1    14.457 ? 1105 PHE A HB3    1 c 
ATOM   1467 H HD1    . PHE A 1 97  ? 29.623  -16.528 24.416  1    16.81  ? 1105 PHE A HD1    1 c 
ATOM   1468 H HD2    . PHE A 1 97  ? 29.103  -15.029 28.386  1    15.67  ? 1105 PHE A HD2    1 c 
ATOM   1469 H HE1    . PHE A 1 97  ? 28.477  -14.528 23.518  1    17.815 ? 1105 PHE A HE1    1 c 
ATOM   1470 H HE2    . PHE A 1 97  ? 27.959  -13.034 27.479  1    16.684 ? 1105 PHE A HE2    1 c 
ATOM   1471 H HZ     . PHE A 1 97  ? 27.645  -12.782 25.043  1    17.848 ? 1105 PHE A HZ     1 c 
ATOM   1472 N N      . ASP A 1 98  ? 29.316  -20.635 27.939  1    13.488 ? 1106 ASP A N      1 ? 
ATOM   1473 C CA     . ASP A 1 98  ? 29.857  -21.723 28.739  1    14.002 ? 1106 ASP A CA     1 ? 
ATOM   1474 C C      . ASP A 1 98  ? 29.489  -23.112 28.223  1    13.87  ? 1106 ASP A C      1 ? 
ATOM   1475 O O      . ASP A 1 98  ? 29.836  -24.101 28.865  1    12.293 ? 1106 ASP A O      1 ? 
ATOM   1476 C CB     . ASP A 1 98  ? 29.431  -21.596 30.205  1    16.237 ? 1106 ASP A CB     1 ? 
ATOM   1477 C CG     . ASP A 1 98  ? 27.934  -21.711 30.428  1    15.279 ? 1106 ASP A CG     1 ? 
ATOM   1478 O OD1    . ASP A 1 98  ? 27.176  -21.888 29.447  1    14.728 ? 1106 ASP A OD1    1 ? 
ATOM   1479 O OD2    . ASP A 1 98  ? 27.506  -21.634 31.599  1    15.908 ? 1106 ASP A OD2    1 ? 
ATOM   1480 H H      . ASP A 1 98  ? 28.297  -20.629 27.754  1    13.473 ? 1106 ASP A H      1 ? 
ATOM   1481 H HA     . ASP A 1 98  ? 30.945  -21.639 28.729  1    14.264 ? 1106 ASP A HA     1 c 
ATOM   1482 H HB2    . ASP A 1 98  ? 29.928  -22.372 30.79   1    15.494 ? 1106 ASP A HB2    1 c 
ATOM   1483 H HB3    . ASP A 1 98  ? 29.755  -20.625 30.583  1    15.51  ? 1106 ASP A HB3    1 c 
ATOM   1484 N N      . GLY A 1 99  ? 28.781  -23.221 27.095  1    13.959 ? 1107 GLY A N      1 ? 
ATOM   1485 C CA     . GLY A 1 99  ? 28.44   -24.533 26.588  1    14.133 ? 1107 GLY A CA     1 ? 
ATOM   1486 C C      . GLY A 1 99  ? 27.409  -25.298 27.403  1    14.709 ? 1107 GLY A C      1 ? 
ATOM   1487 O O      . GLY A 1 99  ? 27.267  -26.505 27.205  1    14.334 ? 1107 GLY A O      1 ? 
ATOM   1488 H H      . GLY A 1 99  ? 28.434  -22.378 26.597  1    13.402 ? 1107 GLY A H      1 ? 
ATOM   1489 H HA2    . GLY A 1 99  ? 28.071  -24.423 25.566  1    14.213 ? 1107 GLY A HA2    1 c 
ATOM   1490 H HA3    . GLY A 1 99  ? 29.356  -25.125 26.541  1    14.207 ? 1107 GLY A HA3    1 c 
ATOM   1491 N N      . ARG A 1 100 ? 26.682  -24.624 28.297  1    15.822 ? 1108 ARG A N      1 ? 
ATOM   1492 C CA     . ARG A 1 100 ? 25.708  -25.322 29.132  1    16.615 ? 1108 ARG A CA     1 ? 
ATOM   1493 C C      . ARG A 1 100 ? 24.264  -24.917 28.865  1    16.186 ? 1108 ARG A C      1 ? 
ATOM   1494 O O      . ARG A 1 100 ? 23.367  -25.587 29.384  1    16.744 ? 1108 ARG A O      1 ? 
ATOM   1495 C CB     . ARG A 1 100 ? 26.011  -25.094 30.62   1    18.69  ? 1108 ARG A CB     1 ? 
ATOM   1496 C CG     . ARG A 1 100 ? 27.356  -25.627 31.074  1    22.537 ? 1108 ARG A CG     1 ? 
ATOM   1497 C CD     . ARG A 1 100 ? 27.574  -25.465 32.58   1    26.179 ? 1108 ARG A CD     1 ? 
ATOM   1498 N NE     . ARG A 1 100 ? 26.799  -26.507 33.279  1    28.724 ? 1108 ARG A NE     1 ? 
ATOM   1499 C CZ     . ARG A 1 100 ? 25.628  -26.355 33.88   1    30.585 ? 1108 ARG A CZ     1 ? 
ATOM   1500 N NH1    . ARG A 1 100 ? 24.981  -25.204 33.811  1    29.138 ? 1108 ARG A NH1    1 ? 
ATOM   1501 N NH2    . ARG A 1 100 ? 25.035  -27.385 34.487  1    32.421 ? 1108 ARG A NH2    1 ? 
ATOM   1502 H H      . ARG A 1 100 ? 26.846  -23.616 28.458  1    15.693 ? 1108 ARG A H      1 ? 
ATOM   1503 H HA     . ARG A 1 100 ? 25.798  -26.392 28.937  1    16.701 ? 1108 ARG A HA     1 c 
ATOM   1504 H HB2    . ARG A 1 100 ? 25.973  -24.021 30.823  1    19.001 ? 1108 ARG A HB2    1 c 
ATOM   1505 H HB3    . ARG A 1 100 ? 25.228  -25.57  31.213  1    19.062 ? 1108 ARG A HB3    1 c 
ATOM   1506 H HG2    . ARG A 1 100 ? 27.428  -26.685 30.817  1    22.328 ? 1108 ARG A HG2    1 c 
ATOM   1507 H HG3    . ARG A 1 100 ? 28.15   -25.098 30.542  1    22.264 ? 1108 ARG A HG3    1 c 
ATOM   1508 H HD2    . ARG A 1 100 ? 28.634  -25.577 32.817  1    25.896 ? 1108 ARG A HD2    1 c 
ATOM   1509 H HD3    . ARG A 1 100 ? 27.249  -24.477 32.904  1    25.933 ? 1108 ARG A HD3    1 c 
ATOM   1510 H HE     . ARG A 1 100 ? 27.166  -27.452 33.244  1    28.501 ? 1108 ARG A HE     1 ? 
ATOM   1511 H HH11   . ARG A 1 100 ? 25.413  -24.39  33.406  1    29.132 ? 1108 ARG A HH11   1 ? 
ATOM   1512 H HH12   . ARG A 1 100 ? 24.041  -25.161 34.191  1    28.668 ? 1108 ARG A HH12   1 ? 
ATOM   1513 H HH21   . ARG A 1 100 ? 25.456  -28.321 34.489  1    30.516 ? 1108 ARG A HH21   1 ? 
ATOM   1514 H HH22   . ARG A 1 100 ? 24.115  -27.231 34.897  1    31.141 ? 1108 ARG A HH22   1 ? 
ATOM   1515 N N      . THR A 1 101 ? 24.015  -23.84  28.106  1    15.686 ? 1109 THR A N      1 ? 
ATOM   1516 C CA     . THR A 1 101 ? 22.648  -23.393 27.884  1    15.021 ? 1109 THR A CA     1 ? 
ATOM   1517 C C      . THR A 1 101 ? 22.41   -23.188 26.402  1    14.329 ? 1109 THR A C      1 ? 
ATOM   1518 O O      . THR A 1 101 ? 23.337  -22.898 25.634  1    13.895 ? 1109 THR A O      1 ? 
ATOM   1519 C CB     . THR A 1 101 ? 22.276  -22.092 28.64   1    13.937 ? 1109 THR A CB     1 ? 
ATOM   1520 O OG1    . THR A 1 101 ? 22.748  -20.926 27.947  1    13.296 ? 1109 THR A OG1    1 ? 
ATOM   1521 C CG2    . THR A 1 101 ? 22.787  -22.1   30.074  1    14.478 ? 1109 THR A CG2    1 ? 
ATOM   1522 H H      . THR A 1 101 ? 24.798  -23.316 27.677  1    15.703 ? 1109 THR A H      1 ? 
ATOM   1523 H HA     . THR A 1 101 ? 21.981  -24.183 28.227  1    14.836 ? 1109 THR A HA     1 c 
ATOM   1524 H HB     . THR A 1 101 ? 21.187  -22.038 28.693  1    14.09  ? 1109 THR A HB     1 c 
ATOM   1525 H HG1    . THR A 1 101 ? 23.707  -20.948 27.879  1    14.243 ? 1109 THR A HG1    1 ? 
ATOM   1526 H HG21   . THR A 1 101 ? 23.877  -22.166 30.074  1    14.338 ? 1109 THR A HG21   1 c 
ATOM   1527 H HG22   . THR A 1 101 ? 22.48   -21.18  30.575  1    14.332 ? 1109 THR A HG22   1 c 
ATOM   1528 H HG23   . THR A 1 101 ? 22.371  -22.958 30.605  1    14.346 ? 1109 THR A HG23   1 c 
ATOM   1529 N N      . GLY A 1 102 ? 21.138  -23.313 26.027  1    14.231 ? 1110 GLY A N      1 ? 
ATOM   1530 C CA     . GLY A 1 102 ? 20.683  -22.913 24.715  1    14.19  ? 1110 GLY A CA     1 ? 
ATOM   1531 C C      . GLY A 1 102 ? 19.432  -22.065 24.87   1    13.481 ? 1110 GLY A C      1 ? 
ATOM   1532 O O      . GLY A 1 102 ? 18.78   -22.083 25.914  1    14.929 ? 1110 GLY A O      1 ? 
ATOM   1533 H H      . GLY A 1 102 ? 20.445  -23.63  26.726  1    14.112 ? 1110 GLY A H      1 ? 
ATOM   1534 H HA2    . GLY A 1 102 ? 21.464  -22.336 24.217  1    14.045 ? 1110 GLY A HA2    1 c 
ATOM   1535 H HA3    . GLY A 1 102 ? 20.468  -23.796 24.11   1    14.063 ? 1110 GLY A HA3    1 c 
ATOM   1536 N N      . SER A 1 103 ? 19.102  -21.319 23.818  1    13.536 ? 1111 SER A N      1 ? 
ATOM   1537 C CA     . SER A 1 103 ? 17.998  -20.376 23.881  1    13.445 ? 1111 SER A CA     1 ? 
ATOM   1538 C C      . SER A 1 103 ? 17.033  -20.575 22.723  1    12.699 ? 1111 SER A C      1 ? 
ATOM   1539 O O      . SER A 1 103 ? 17.433  -20.923 21.611  1    13.58  ? 1111 SER A O      1 ? 
ATOM   1540 C CB     . SER A 1 103 ? 18.477  -18.947 23.887  1    13.432 ? 1111 SER A CB     1 ? 
ATOM   1541 O OG     . SER A 1 103 ? 19.355  -18.771 24.981  1    14.046 ? 1111 SER A OG     1 ? 
ATOM   1542 H H      . SER A 1 103 ? 19.682  -21.353 22.958  1    13.034 ? 1111 SER A H      1 ? 
ATOM   1543 H HA     . SER A 1 103 ? 17.456  -20.558 24.807  1    13.36  ? 1111 SER A HA     1 c 
ATOM   1544 H HB2    . SER A 1 103 ? 19      -18.728 22.953  1    13.575 ? 1111 SER A HB2    1 c 
ATOM   1545 H HB3    . SER A 1 103 ? 17.624  -18.272 23.983  1    13.575 ? 1111 SER A HB3    1 c 
ATOM   1546 H HG     . SER A 1 103 ? 19.641  -17.843 25.027  1    14.218 ? 1111 SER A HG     1 ? 
ATOM   1547 N N      . LEU A 1 104 ? 15.757  -20.303 22.995  1    12.477 ? 1112 LEU A N      1 ? 
ATOM   1548 C CA     . LEU A 1 104 ? 14.687  -20.358 22.017  1    12.939 ? 1112 LEU A CA     1 ? 
ATOM   1549 C C      . LEU A 1 104 ? 14.014  -18.991 21.922  1    14.607 ? 1112 LEU A C      1 ? 
ATOM   1550 O O      . LEU A 1 104 ? 13.984  -18.221 22.892  1    14.423 ? 1112 LEU A O      1 ? 
ATOM   1551 C CB     . LEU A 1 104 ? 13.639  -21.414 22.393  1    11.065 ? 1112 LEU A CB     1 ? 
ATOM   1552 C CG     . LEU A 1 104 ? 14.163  -22.829 22.647  1    11.97  ? 1112 LEU A CG     1 ? 
ATOM   1553 C CD1    . LEU A 1 104 ? 13.06   -23.794 22.967  1    12.946 ? 1112 LEU A CD1    1 ? 
ATOM   1554 C CD2    . LEU A 1 104 ? 14.946  -23.358 21.454  1    12.977 ? 1112 LEU A CD2    1 ? 
ATOM   1555 H H      . LEU A 1 104 ? 15.514  -19.978 23.947  1    12.099 ? 1112 LEU A H      1 ? 
ATOM   1556 H HA     . LEU A 1 104 ? 15.116  -20.607 21.044  1    12.78  ? 1112 LEU A HA     1 c 
ATOM   1557 H HB2    . LEU A 1 104 ? 13.121  -21.073 23.292  1    11.648 ? 1112 LEU A HB2    1 c 
ATOM   1558 H HB3    . LEU A 1 104 ? 12.901  -21.461 21.59   1    11.648 ? 1112 LEU A HB3    1 c 
ATOM   1559 H HG     . LEU A 1 104 ? 14.838  -22.792 23.504  1    12.149 ? 1112 LEU A HG     1 c 
ATOM   1560 H HD11   . LEU A 1 104 ? 13.481  -24.786 23.14   1    12.652 ? 1112 LEU A HD11   1 c 
ATOM   1561 H HD12   . LEU A 1 104 ? 12.533  -23.462 23.864  1    12.652 ? 1112 LEU A HD12   1 c 
ATOM   1562 H HD13   . LEU A 1 104 ? 12.359  -23.838 22.13   1    12.616 ? 1112 LEU A HD13   1 c 
ATOM   1563 H HD21   . LEU A 1 104 ? 15.815  -22.723 21.275  1    12.687 ? 1112 LEU A HD21   1 c 
ATOM   1564 H HD22   . LEU A 1 104 ? 15.278  -24.378 21.659  1    12.681 ? 1112 LEU A HD22   1 c 
ATOM   1565 H HD23   . LEU A 1 104 ? 14.307  -23.356 20.568  1    12.651 ? 1112 LEU A HD23   1 c 
ATOM   1566 N N      . CYS A 1 105 ? 13.465  -18.716 20.739  1    14.494 ? 1113 CYS A N      1 ? 
ATOM   1567 C CA     . CYS A 1 105 ? 12.747  -17.497 20.402  1    15.484 ? 1113 CYS A CA     1 ? 
ATOM   1568 C C      . CYS A 1 105 ? 11.335  -17.94  20.024  1    16.644 ? 1113 CYS A C      1 ? 
ATOM   1569 O O      . CYS A 1 105 ? 11.126  -18.462 18.922  1    14.779 ? 1113 CYS A O      1 ? 
ATOM   1570 C CB     . CYS A 1 105 ? 13.447  -16.822 19.22   1    16.884 ? 1113 CYS A CB     1 ? 
ATOM   1571 S SG     . CYS A 1 105 ? 12.643  -15.309 18.638  1    16.008 ? 1113 CYS A SG     1 ? 
ATOM   1572 H H      . CYS A 1 105 ? 13.575  -19.402 19.969  1    14.866 ? 1113 CYS A H      1 ? 
ATOM   1573 H HA     . CYS A 1 105 ? 12.708  -16.849 21.277  1    15.708 ? 1113 CYS A HA     1 c 
ATOM   1574 H HB2    . CYS A 1 105 ? 14.472  -16.579 19.507  1    16.373 ? 1113 CYS A HB2    1 c 
ATOM   1575 H HB3    . CYS A 1 105 ? 13.493  -17.527 18.388  1    16.38  ? 1113 CYS A HB3    1 c 
ATOM   1576 H HG     . CYS A 1 105 ? 13.113  -14.521 19.642  1    15.745 ? 1113 CYS A HG     1 ? 
ATOM   1577 N N      . VAL A 1 106 ? 10.376  -17.741 20.938  1    17.934 ? 1114 VAL A N      1 ? 
ATOM   1578 C CA     . VAL A 1 106 ? 9.088   -18.44  20.883  1    18.156 ? 1114 VAL A CA     1 ? 
ATOM   1579 C C      . VAL A 1 106 ? 7.945   -17.433 20.79   1    17.794 ? 1114 VAL A C      1 ? 
ATOM   1580 O O      . VAL A 1 106 ? 7.752   -16.608 21.688  1    16.208 ? 1114 VAL A O      1 ? 
ATOM   1581 C CB     . VAL A 1 106 ? 8.901   -19.348 22.109  1    17.208 ? 1114 VAL A CB     1 ? 
ATOM   1582 C CG1    . VAL A 1 106 ? 7.54    -20.026 22.08   1    18.651 ? 1114 VAL A CG1    1 ? 
ATOM   1583 C CG2    . VAL A 1 106 ? 10.037  -20.372 22.173  1    18.936 ? 1114 VAL A CG2    1 ? 
ATOM   1584 H H      . VAL A 1 106 ? 10.558  -17.102 21.732  1    19.379 ? 1114 VAL A H      1 ? 
ATOM   1585 H HA     . VAL A 1 106 ? 9.072   -19.064 19.987  1    17.854 ? 1114 VAL A HA     1 c 
ATOM   1586 H HB     . VAL A 1 106 ? 8.955   -18.716 22.997  1    17.931 ? 1114 VAL A HB     1 c 
ATOM   1587 H HG11   . VAL A 1 106 ? 6.754   -19.278 22.198  1    18.236 ? 1114 VAL A HG11   1 c 
ATOM   1588 H HG12   . VAL A 1 106 ? 7.409   -20.544 21.128  1    18.237 ? 1114 VAL A HG12   1 c 
ATOM   1589 H HG13   . VAL A 1 106 ? 7.475   -20.748 22.898  1    18.236 ? 1114 VAL A HG13   1 c 
ATOM   1590 H HG21   . VAL A 1 106 ? 10.991  -19.856 22.298  1    18.587 ? 1114 VAL A HG21   1 c 
ATOM   1591 H HG22   . VAL A 1 106 ? 9.873   -21.047 23.015  1    18.586 ? 1114 VAL A HG22   1 c 
ATOM   1592 H HG23   . VAL A 1 106 ? 10.057  -20.95  21.247  1    18.488 ? 1114 VAL A HG23   1 c 
ATOM   1593 N N      . ARG A 1 107 ? 7.159   -17.539 19.72   1    19.273 ? 1115 ARG A N      1 ? 
ATOM   1594 C CA     . ARG A 1 107 ? 5.947   -16.742 19.553  1    19.076 ? 1115 ARG A CA     1 ? 
ATOM   1595 C C      . ARG A 1 107 ? 4.759   -17.451 20.204  1    16.843 ? 1115 ARG A C      1 ? 
ATOM   1596 O O      . ARG A 1 107 ? 4.464   -18.606 19.881  1    17.068 ? 1115 ARG A O      1 ? 
ATOM   1597 C CB     . ARG A 1 107 ? 5.663   -16.525 18.065  1    20.791 ? 1115 ARG A CB     1 ? 
ATOM   1598 C CG     . ARG A 1 107 ? 4.512   -15.562 17.808  1    21.989 ? 1115 ARG A CG     1 ? 
ATOM   1599 C CD     . ARG A 1 107 ? 4.153   -15.457 16.351  1    23.994 ? 1115 ARG A CD     1 ? 
ATOM   1600 N NE     . ARG A 1 107 ? 3.607   -16.75  15.904  1    25.644 ? 1115 ARG A NE     1 ? 
ATOM   1601 C CZ     . ARG A 1 107 ? 2.343   -17.115 15.986  1    30.288 ? 1115 ARG A CZ     1 ? 
ATOM   1602 N NH1    . ARG A 1 107 ? 1.439   -16.257 16.429  1    30.85  ? 1115 ARG A NH1    1 ? 
ATOM   1603 N NH2    . ARG A 1 107 ? 1.993   -18.334 15.707  1    32.603 ? 1115 ARG A NH2    1 ? 
ATOM   1604 H H      . ARG A 1 107 ? 7.406   -18.219 18.984  1    18.84  ? 1115 ARG A H      1 ? 
ATOM   1605 H HA     . ARG A 1 107 ? 6.094   -15.775 20.038  1    18.917 ? 1115 ARG A HA     1 c 
ATOM   1606 H HB2    . ARG A 1 107 ? 6.563   -16.135 17.586  1    20.662 ? 1115 ARG A HB2    1 c 
ATOM   1607 H HB3    . ARG A 1 107 ? 5.429   -17.487 17.606  1    20.682 ? 1115 ARG A HB3    1 c 
ATOM   1608 H HG2    . ARG A 1 107 ? 3.633   -15.894 18.364  1    22.114 ? 1115 ARG A HG2    1 c 
ATOM   1609 H HG3    . ARG A 1 107 ? 4.785   -14.571 18.177  1    22.14  ? 1115 ARG A HG3    1 c 
ATOM   1610 H HD2    . ARG A 1 107 ? 3.419   -14.668 16.19   1    24.189 ? 1115 ARG A HD2    1 c 
ATOM   1611 H HD3    . ARG A 1 107 ? 5.046   -15.22  15.769  1    24.03  ? 1115 ARG A HD3    1 c 
ATOM   1612 H HE     . ARG A 1 107 ? 4.241   -17.489 15.599  1    28.02  ? 1115 ARG A HE     1 ? 
ATOM   1613 H HH11   . ARG A 1 107 ? 1.63    -15.251 16.513  1    26.448 ? 1115 ARG A HH11   1 ? 
ATOM   1614 H HH12   . ARG A 1 107 ? 0.528   -16.633 16.662  1    31.227 ? 1115 ARG A HH12   1 ? 
ATOM   1615 H HH21   . ARG A 1 107 ? 2.607   -18.942 15.18   1    31.495 ? 1115 ARG A HH21   1 ? 
ATOM   1616 H HH22   . ARG A 1 107 ? 1.088   -18.608 16.09   1    34.192 ? 1115 ARG A HH22   1 ? 
ATOM   1617 N N      . ARG A 1 108 ? 4.08    -16.759 21.101  1    16.633 ? 1116 ARG A N      1 ? 
ATOM   1618 C CA     . ARG A 1 108 ? 2.894   -17.324 21.725  1    19.515 ? 1116 ARG A CA     1 ? 
ATOM   1619 C C      . ARG A 1 108 ? 1.794   -17.483 20.679  1    17.989 ? 1116 ARG A C      1 ? 
ATOM   1620 O O      . ARG A 1 108 ? 1.401   -16.508 20.026  1    17.465 ? 1116 ARG A O      1 ? 
ATOM   1621 C CB     . ARG A 1 108 ? 2.354   -16.315 22.719  1    20.957 ? 1116 ARG A CB     1 ? 
ATOM   1622 C CG     . ARG A 1 108 ? 2.931   -16.426 24.077  1    25.878 ? 1116 ARG A CG     1 ? 
ATOM   1623 C CD     . ARG A 1 108 ? 1.902   -15.76  24.987  1    23.565 ? 1116 ARG A CD     1 ? 
ATOM   1624 N NE     . ARG A 1 108 ? 2.553   -15.466 26.249  1    25.488 ? 1116 ARG A NE     1 ? 
ATOM   1625 C CZ     . ARG A 1 108 ? 2.485   -16.241 27.322  1    22.903 ? 1116 ARG A CZ     1 ? 
ATOM   1626 N NH1    . ARG A 1 108 ? 1.799   -17.371 27.315  1    22.209 ? 1116 ARG A NH1    1 ? 
ATOM   1627 N NH2    . ARG A 1 108 ? 3.187   -15.925 28.39   1    20.593 ? 1116 ARG A NH2    1 ? 
ATOM   1628 H H      . ARG A 1 108 ? 4.315   -15.768 21.298  1    15.356 ? 1116 ARG A H      1 ? 
ATOM   1629 H HA     . ARG A 1 108 ? 3.134   -18.283 22.188  1    18.901 ? 1116 ARG A HA     1 c 
ATOM   1630 H HB2    . ARG A 1 108 ? 2.547   -15.31  22.338  1    21.57  ? 1116 ARG A HB2    1 c 
ATOM   1631 H HB3    . ARG A 1 108 ? 1.271   -16.44  22.788  1    21.61  ? 1116 ARG A HB3    1 c 
ATOM   1632 H HG2    . ARG A 1 108 ? 3.058   -17.474 24.356  1    24.196 ? 1116 ARG A HG2    1 c 
ATOM   1633 H HG3    . ARG A 1 108 ? 3.882   -15.893 24.133  1    24.171 ? 1116 ARG A HG3    1 c 
ATOM   1634 H HD2    . ARG A 1 108 ? 1.549   -14.831 24.535  1    24.477 ? 1116 ARG A HD2    1 c 
ATOM   1635 H HD3    . ARG A 1 108 ? 1.045   -16.413 25.151  1    24.398 ? 1116 ARG A HD3    1 c 
ATOM   1636 H HE     . ARG A 1 108 ? 3.155   -14.64  26.283  1    25.515 ? 1116 ARG A HE     1 ? 
ATOM   1637 H HH11   . ARG A 1 108 ? 1.206   -17.713 26.568  1    22.262 ? 1116 ARG A HH11   1 ? 
ATOM   1638 H HH12   . ARG A 1 108 ? 1.887   -17.896 28.196  1    20.909 ? 1116 ARG A HH12   1 ? 
ATOM   1639 H HH21   . ARG A 1 108 ? 3.57    -15.023 28.37   1    21.24  ? 1116 ARG A HH21   1 ? 
ATOM   1640 H HH22   . ARG A 1 108 ? 3.194   -16.554 29.208  1    20.731 ? 1116 ARG A HH22   1 ? 
ATOM   1641 N N      . ALA A 1 109 ? 1.263   -18.696 20.523  1    19.733 ? 1117 ALA A N      1 ? 
ATOM   1642 C CA     . ALA A 1 109 ? 0.127   -18.937 19.644  1    21.33  ? 1117 ALA A CA     1 ? 
ATOM   1643 C C      . ALA A 1 109 ? -1.167  -18.839 20.456  1    23.173 ? 1117 ALA A C      1 ? 
ATOM   1644 O O      . ALA A 1 109 ? -1.451  -19.71  21.29   1    20.289 ? 1117 ALA A O      1 ? 
ATOM   1645 C CB     . ALA A 1 109 ? 0.272   -20.29  18.958  1    21.836 ? 1117 ALA A CB     1 ? 
ATOM   1646 H H      . ALA A 1 109 ? 1.736   -19.511 20.946  1    21.297 ? 1117 ALA A H      1 ? 
ATOM   1647 H HA     . ALA A 1 109 ? 0.111   -18.155 18.883  1    21.426 ? 1117 ALA A HA     1 c 
ATOM   1648 H HB1    . ALA A 1 109 ? 1.174   -20.295 18.343  1    21.681 ? 1117 ALA A HB1    1 c 
ATOM   1649 H HB2    . ALA A 1 109 ? 0.344   -21.077 19.71   1    21.667 ? 1117 ALA A HB2    1 c 
ATOM   1650 H HB3    . ALA A 1 109 ? -0.598  -20.474 18.324  1    21.652 ? 1117 ALA A HB3    1 c 
ATOM   1651 N N      . VAL A 1 110 ? -1.925  -17.767 20.232  1    24.65  ? 1118 VAL A N      1 ? 
ATOM   1652 C CA     . VAL A 1 110 ? -3.145  -17.468 20.977  1    29.554 ? 1118 VAL A CA     1 ? 
ATOM   1653 C C      . VAL A 1 110 ? -4.334  -17.479 20.019  1    26.073 ? 1118 VAL A C      1 ? 
ATOM   1654 O O      . VAL A 1 110 ? -4.259  -16.928 18.928  1    22.812 ? 1118 VAL A O      1 ? 
ATOM   1655 C CB     . VAL A 1 110 ? -3.068  -16.126 21.733  1    33.724 ? 1118 VAL A CB     1 ? 
ATOM   1656 C CG1    . VAL A 1 110 ? -4.261  -15.959 22.658  1    38.823 ? 1118 VAL A CG1    1 ? 
ATOM   1657 C CG2    . VAL A 1 110 ? -1.781  -16.014 22.522  1    34.465 ? 1118 VAL A CG2    1 ? 
ATOM   1658 H H      . VAL A 1 110 ? -1.592  -17.087 19.536  1    26.235 ? 1118 VAL A H      1 ? 
ATOM   1659 H HA     . VAL A 1 110 ? -3.294  -18.26  21.711  1    28.496 ? 1118 VAL A HA     1 c 
ATOM   1660 H HB     . VAL A 1 110 ? -3.09   -15.327 20.989  1    33.914 ? 1118 VAL A HB     1 c 
ATOM   1661 H HG11   . VAL A 1 110 ? -5.183  -15.967 22.074  1    37.216 ? 1118 VAL A HG11   1 c 
ATOM   1662 H HG12   . VAL A 1 110 ? -4.281  -16.777 23.38   1    37.265 ? 1118 VAL A HG12   1 c 
ATOM   1663 H HG13   . VAL A 1 110 ? -4.178  -15.009 23.191  1    37.154 ? 1118 VAL A HG13   1 c 
ATOM   1664 H HG21   . VAL A 1 110 ? -1.797  -15.099 23.117  1    34.197 ? 1118 VAL A HG21   1 c 
ATOM   1665 H HG22   . VAL A 1 110 ? -1.684  -16.876 23.185  1    34.205 ? 1118 VAL A HG22   1 c 
ATOM   1666 H HG23   . VAL A 1 110 ? -0.932  -15.987 21.835  1    34.053 ? 1118 VAL A HG23   1 c 
ATOM   1667 N N      . TYR A 1 111 ? -5.428  -18.102 20.447  1    25.197 ? 1119 TYR A N      1 ? 
ATOM   1668 C CA     . TYR A 1 111 ? -6.64   -18.158 19.656  1    28.072 ? 1119 TYR A CA     1 ? 
ATOM   1669 C C      . TYR A 1 111 ? -7.586  -17.016 19.993  1    25.113 ? 1119 TYR A C      1 ? 
ATOM   1670 O O      . TYR A 1 111 ? -7.851  -16.74  21.16   1    23.304 ? 1119 TYR A O      1 ? 
ATOM   1671 C CB     . TYR A 1 111 ? -7.363  -19.488 19.86   1    30.899 ? 1119 TYR A CB     1 ? 
ATOM   1672 C CG     . TYR A 1 111 ? -8.693  -19.573 19.129  1    32.884 ? 1119 TYR A CG     1 ? 
ATOM   1673 C CD1    . TYR A 1 111 ? -8.799  -19.79  17.758  1    31.03  ? 1119 TYR A CD1    1 ? 
ATOM   1674 C CD2    . TYR A 1 111 ? -9.851  -19.304 19.834  1    36.748 ? 1119 TYR A CD2    1 ? 
ATOM   1675 C CE1    . TYR A 1 111 ? -10.015 -19.826 17.126  1    34.245 ? 1119 TYR A CE1    1 ? 
ATOM   1676 C CE2    . TYR A 1 111 ? -11.092 -19.357 19.214  1    31.626 ? 1119 TYR A CE2    1 ? 
ATOM   1677 C CZ     . TYR A 1 111 ? -11.165 -19.609 17.857  1    32.545 ? 1119 TYR A CZ     1 ? 
ATOM   1678 O OH     . TYR A 1 111 ? -12.381 -19.663 17.233  1    32.324 ? 1119 TYR A OH     1 ? 
ATOM   1679 H H      . TYR A 1 111 ? -5.394  -18.616 21.35   1    24.991 ? 1119 TYR A H      1 ? 
ATOM   1680 H HA     . TYR A 1 111 ? -6.364  -18.078 18.604  1    27.481 ? 1119 TYR A HA     1 c 
ATOM   1681 H HB2    . TYR A 1 111 ? -6.714  -20.294 19.512  1    30.673 ? 1119 TYR A HB2    1 c 
ATOM   1682 H HB3    . TYR A 1 111 ? -7.537  -19.629 20.929  1    30.673 ? 1119 TYR A HB3    1 c 
ATOM   1683 H HD1    . TYR A 1 111 ? -7.9    -19.972 17.18   1    32.143 ? 1119 TYR A HD1    1 c 
ATOM   1684 H HD2    . TYR A 1 111 ? -9.796  -19.12  20.902  1    34.628 ? 1119 TYR A HD2    1 c 
ATOM   1685 H HE1    . TYR A 1 111 ? -10.076 -20.038 16.064  1    33.13  ? 1119 TYR A HE1    1 c 
ATOM   1686 H HE2    . TYR A 1 111 ? -11.997 -19.183 19.786  1    32.804 ? 1119 TYR A HE2    1 c 
ATOM   1687 H HH     . TYR A 1 111 ? -12.243 -19.785 16.281  1    32.608 ? 1119 TYR A HH     1 ? 
ATOM   1688 N N      . TYR A 1 112 ? -8.106  -16.379 18.945  1    28.04  ? 1120 TYR A N      1 ? 
ATOM   1689 C CA     . TYR A 1 112 ? -9.143  -15.373 19.072  1    30.628 ? 1120 TYR A CA     1 ? 
ATOM   1690 C C      . TYR A 1 112 ? -10.276 -15.718 18.12   1    31.877 ? 1120 TYR A C      1 ? 
ATOM   1691 O O      . TYR A 1 112 ? -10.043 -16.062 16.962  1    31.697 ? 1120 TYR A O      1 ? 
ATOM   1692 C CB     . TYR A 1 112 ? -8.607  -13.977 18.739  1    34.222 ? 1120 TYR A CB     1 ? 
ATOM   1693 C CG     . TYR A 1 112 ? -7.399  -13.523 19.552  1    38.818 ? 1120 TYR A CG     1 ? 
ATOM   1694 C CD1    . TYR A 1 112 ? -6.095  -13.808 19.137  1    39.864 ? 1120 TYR A CD1    1 ? 
ATOM   1695 C CD2    . TYR A 1 112 ? -7.56   -12.821 20.748  1    40.505 ? 1120 TYR A CD2    1 ? 
ATOM   1696 C CE1    . TYR A 1 112 ? -4.993  -13.424 19.891  1    38.372 ? 1120 TYR A CE1    1 ? 
ATOM   1697 C CE2    . TYR A 1 112 ? -6.468  -12.429 21.51   1    40.741 ? 1120 TYR A CE2    1 ? 
ATOM   1698 C CZ     . TYR A 1 112 ? -5.185  -12.727 21.075  1    43.088 ? 1120 TYR A CZ     1 ? 
ATOM   1699 O OH     . TYR A 1 112 ? -4.112  -12.33  21.827  1    45.696 ? 1120 TYR A OH     1 ? 
ATOM   1700 H H      . TYR A 1 112 ? -7.756  -16.604 17.998  1    26.606 ? 1120 TYR A H      1 ? 
ATOM   1701 H HA     . TYR A 1 112 ? -9.522  -15.376 20.095  1    30.842 ? 1120 TYR A HA     1 c 
ATOM   1702 H HB2    . TYR A 1 112 ? -8.341  -13.957 17.68   1    34.335 ? 1120 TYR A HB2    1 c 
ATOM   1703 H HB3    . TYR A 1 112 ? -9.415  -13.258 18.885  1    34.335 ? 1120 TYR A HB3    1 c 
ATOM   1704 H HD1    . TYR A 1 112 ? -5.939  -14.36  18.216  1    39.317 ? 1120 TYR A HD1    1 c 
ATOM   1705 H HD2    . TYR A 1 112 ? -8.558  -12.59  21.099  1    40.15  ? 1120 TYR A HD2    1 c 
ATOM   1706 H HE1    . TYR A 1 112 ? -3.989  -13.653 19.55   1    39.71  ? 1120 TYR A HE1    1 c 
ATOM   1707 H HE2    . TYR A 1 112 ? -6.616  -11.883 22.436  1    41.162 ? 1120 TYR A HE2    1 c 
ATOM   1708 H HH     . TYR A 1 112 ? -4.415  -11.857 22.614  1    44.507 ? 1120 TYR A HH     1 ? 
ATOM   1709 N N      . ASP A 1 113 ? -11.515 -15.655 18.62   1    27.931 ? 1121 ASP A N      1 ? 
ATOM   1710 C CA     . ASP A 1 113 ? -12.647 -15.895 17.742  1    28.967 ? 1121 ASP A CA     1 ? 
ATOM   1711 C C      . ASP A 1 113 ? -12.583 -14.869 16.615  1    26.468 ? 1121 ASP A C      1 ? 
ATOM   1712 O O      . ASP A 1 113 ? -12.357 -13.682 16.867  1    26.735 ? 1121 ASP A O      1 ? 
ATOM   1713 C CB     . ASP A 1 113 ? -13.962 -15.764 18.472  1    28.442 ? 1121 ASP A CB     1 ? 
ATOM   1714 C CG     . ASP A 1 113 ? -15.157 -15.934 17.55   1    27.354 ? 1121 ASP A CG     1 ? 
ATOM   1715 O OD1    . ASP A 1 113 ? -15.528 -17.086 17.278  1    25.675 ? 1121 ASP A OD1    1 ? 
ATOM   1716 O OD2    . ASP A 1 113 ? -15.7   -14.912 17.081  1    27.421 ? 1121 ASP A OD2    1 ? 
ATOM   1717 H H      . ASP A 1 113 ? -11.676 -15.322 19.584  1    26.295 ? 1121 ASP A H      1 ? 
ATOM   1718 H HA     . ASP A 1 113 ? -12.56  -16.9   17.33   1    28.193 ? 1121 ASP A HA     1 c 
ATOM   1719 H HB2    . ASP A 1 113 ? -14.017 -16.518 19.26   1    28.319 ? 1121 ASP A HB2    1 c 
ATOM   1720 H HB3    . ASP A 1 113 ? -14.006 -14.778 18.936  1    28.343 ? 1121 ASP A HB3    1 c 
ATOM   1721 N N      . PRO A 1 114 ? -12.754 -15.278 15.344  1    26.277 ? 1122 PRO A N      1 ? 
ATOM   1722 C CA     . PRO A 1 114 ? -12.527 -14.331 14.255  1    28.135 ? 1122 PRO A CA     1 ? 
ATOM   1723 C C      . PRO A 1 114 ? -13.526 -13.175 14.263  1    29.577 ? 1122 PRO A C      1 ? 
ATOM   1724 O O      . PRO A 1 114 ? -13.252 -12.141 13.666  1    33.522 ? 1122 PRO A O      1 ? 
ATOM   1725 C CB     . PRO A 1 114 ? -12.611 -15.19  12.993  1    27.759 ? 1122 PRO A CB     1 ? 
ATOM   1726 C CG     . PRO A 1 114 ? -12.576 -16.626 13.476  1    24.666 ? 1122 PRO A CG     1 ? 
ATOM   1727 C CD     . PRO A 1 114 ? -13.121 -16.617 14.865  1    26.421 ? 1122 PRO A CD     1 ? 
ATOM   1728 H HA     . PRO A 1 114 ? -11.516 -13.928 14.342  1    27.957 ? 1122 PRO A HA     1 c 
ATOM   1729 H HB2    . PRO A 1 114 ? -13.536 -14.988 12.45   1    27.134 ? 1122 PRO A HB2    1 c 
ATOM   1730 H HB3    . PRO A 1 114 ? -11.768 -14.986 12.33   1    27.134 ? 1122 PRO A HB3    1 c 
ATOM   1731 H HG2    . PRO A 1 114 ? -13.188 -17.262 12.833  1    25.689 ? 1122 PRO A HG2    1 c 
ATOM   1732 H HG3    . PRO A 1 114 ? -11.553 -17.008 13.472  1    25.689 ? 1122 PRO A HG3    1 c 
ATOM   1733 H HD2    . PRO A 1 114 ? -14.203 -16.749 14.87   1    26.173 ? 1122 PRO A HD2    1 c 
ATOM   1734 H HD3    . PRO A 1 114 ? -12.658 -17.393 15.476  1    26.065 ? 1122 PRO A HD3    1 c 
ATOM   1735 N N      . GLU A 1 115 ? -14.676 -13.334 14.943  1    30.48  ? 1123 GLU A N      1 ? 
ATOM   1736 C CA     . GLU A 1 115 ? -15.672 -12.277 15.001  1    30.401 ? 1123 GLU A CA     1 ? 
ATOM   1737 C C      . GLU A 1 115 ? -15.593 -11.509 16.326  1    34.027 ? 1123 GLU A C      1 ? 
ATOM   1738 O O      . GLU A 1 115 ? -15.508 -10.282 16.307  1    40.029 ? 1123 GLU A O      1 ? 
ATOM   1739 C CB     . GLU A 1 115 ? -17.052 -12.853 14.662  1    33.72  ? 1123 GLU A CB     1 ? 
ATOM   1740 C CG     . GLU A 1 115 ? -18.172 -11.822 14.778  1    42.824 ? 1123 GLU A CG     1 ? 
ATOM   1741 C CD     . GLU A 1 115 ? -19.412 -12.101 13.938  1    46.264 ? 1123 GLU A CD     1 ? 
ATOM   1742 O OE1    . GLU A 1 115 ? -19.253 -12.344 12.714  1    45.464 ? 1123 GLU A OE1    1 ? 
ATOM   1743 O OE2    . GLU A 1 115 ? -20.529 -12.051 14.502  1    45.224 ? 1123 GLU A OE2    1 ? 
ATOM   1744 H H      . GLU A 1 115 ? -14.893 -14.238 15.396  1    28.149 ? 1123 GLU A H      1 ? 
ATOM   1745 H HA     . GLU A 1 115 ? -15.441 -11.566 14.206  1    31.618 ? 1123 GLU A HA     1 c 
ATOM   1746 H HB2    . GLU A 1 115 ? -17.029 -13.245 13.643  1    34.79  ? 1123 GLU A HB2    1 c 
ATOM   1747 H HB3    . GLU A 1 115 ? -17.262 -13.686 15.335  1    34.748 ? 1123 GLU A HB3    1 c 
ATOM   1748 H HG2    . GLU A 1 115 ? -18.475 -11.754 15.824  1    41.346 ? 1123 GLU A HG2    1 c 
ATOM   1749 H HG3    . GLU A 1 115 ? -17.779 -10.844 14.493  1    41.338 ? 1123 GLU A HG3    1 c 
ATOM   1750 N N      . THR A 1 116 ? -15.648 -12.2   17.469  1    30.515 ? 1124 THR A N      1 ? 
ATOM   1751 C CA     . THR A 1 116 ? -15.757 -11.533 18.762  1    36.115 ? 1124 THR A CA     1 ? 
ATOM   1752 C C      . THR A 1 116 ? -14.402 -11.121 19.348  1    37.893 ? 1124 THR A C      1 ? 
ATOM   1753 O O      . THR A 1 116 ? -14.399 -10.273 20.239  1    41.561 ? 1124 THR A O      1 ? 
ATOM   1754 C CB     . THR A 1 116 ? -16.498 -12.413 19.775  1    33.001 ? 1124 THR A CB     1 ? 
ATOM   1755 O OG1    . THR A 1 116 ? -15.883 -13.688 19.655  1    32.417 ? 1124 THR A OG1    1 ? 
ATOM   1756 C CG2    . THR A 1 116 ? -17.982 -12.568 19.485  1    32.878 ? 1124 THR A CG2    1 ? 
ATOM   1757 H H      . THR A 1 116 ? -15.609 -13.235 17.439  1    29.034 ? 1124 THR A H      1 ? 
ATOM   1758 H HA     . THR A 1 116 ? -16.349 -10.627 18.615  1    34.747 ? 1124 THR A HA     1 c 
ATOM   1759 H HB     . THR A 1 116 ? -16.353 -12.028 20.787  1    33.385 ? 1124 THR A HB     1 c 
ATOM   1760 H HG1    . THR A 1 116 ? -16.37  -14.318 20.2    1    33.04  ? 1124 THR A HG1    1 ? 
ATOM   1761 H HG21   . THR A 1 116 ? -18.449 -11.583 19.459  1    33.228 ? 1124 THR A HG21   1 c 
ATOM   1762 H HG22   . THR A 1 116 ? -18.115 -13.058 18.518  1    32.998 ? 1124 THR A HG22   1 c 
ATOM   1763 H HG23   . THR A 1 116 ? -18.447 -13.172 20.266  1    33.037 ? 1124 THR A HG23   1 c 
ATOM   1764 N N      . GLY A 1 117 ? -13.284 -11.773 18.971  1    35.566 ? 1125 GLY A N      1 ? 
ATOM   1765 C CA     . GLY A 1 117 ? -12.025 -11.623 19.692  1    35.203 ? 1125 GLY A CA     1 ? 
ATOM   1766 C C      . GLY A 1 117 ? -11.877 -12.54  20.913  1    40.357 ? 1125 GLY A C      1 ? 
ATOM   1767 O O      . GLY A 1 117 ? -10.78  -12.659 21.461  1    38.62  ? 1125 GLY A O      1 ? 
ATOM   1768 H H      . GLY A 1 117 ? -13.283 -12.338 18.107  1    38.271 ? 1125 GLY A H      1 ? 
ATOM   1769 H HA2    . GLY A 1 117 ? -11.207 -11.826 18.998  1    36.351 ? 1125 GLY A HA2    1 c 
ATOM   1770 H HA3    . GLY A 1 117 ? -11.927 -10.584 20.014  1    36.419 ? 1125 GLY A HA3    1 c 
ATOM   1771 N N      . LYS A 1 118 ? -12.966 -13.189 21.35   1    41.577 ? 1126 LYS A N      1 ? 
ATOM   1772 C CA     . LYS A 1 118 ? -12.973 -14.021 22.562  1    42.884 ? 1126 LYS A CA     1 ? 
ATOM   1773 C C      . LYS A 1 118 ? -11.922 -15.15  22.505  1    39.295 ? 1126 LYS A C      1 ? 
ATOM   1774 O O      . LYS A 1 118 ? -11.837 -15.883 21.518  1    33.377 ? 1126 LYS A O      1 ? 
ATOM   1775 C CB     . LYS A 1 118 ? -14.384 -14.571 22.854  1    41.319 ? 1126 LYS A CB     1 ? 
ATOM   1776 C CG     . LYS A 1 118 ? -15.345 -13.596 23.573  1    43.331 ? 1126 LYS A CG     1 ? 
ATOM   1777 C CD     . LYS A 1 118 ? -16.767 -14.111 23.826  1    47.891 ? 1126 LYS A CD     1 ? 
ATOM   1778 C CE     . LYS A 1 118 ? -17.762 -13.21  24.563  1    50.378 ? 1126 LYS A CE     1 ? 
ATOM   1779 N NZ     . LYS A 1 118 ? -19.179 -13.538 24.259  1    55.955 ? 1126 LYS A NZ     1 ? 
ATOM   1780 H H      . LYS A 1 118 ? -13.843 -13.088 20.808  1    39.132 ? 1126 LYS A H      1 ? 
ATOM   1781 H HA     . LYS A 1 118 ? -12.71  -13.373 23.401  1    41.614 ? 1126 LYS A HA     1 c 
ATOM   1782 H HB2    . LYS A 1 118 ? -14.842 -14.868 21.908  1    42.086 ? 1126 LYS A HB2    1 c 
ATOM   1783 H HB3    . LYS A 1 118 ? -14.285 -15.468 23.468  1    42.086 ? 1126 LYS A HB3    1 c 
ATOM   1784 H HG2    . LYS A 1 118 ? -14.898 -13.326 24.532  1    43.832 ? 1126 LYS A HG2    1 c 
ATOM   1785 H HG3    . LYS A 1 118 ? -15.408 -12.683 22.978  1    43.832 ? 1126 LYS A HG3    1 c 
ATOM   1786 H HD2    . LYS A 1 118 ? -17.199 -14.369 22.858  1    47.189 ? 1126 LYS A HD2    1 c 
ATOM   1787 H HD3    . LYS A 1 118 ? -16.681 -15.046 24.38   1    47.331 ? 1126 LYS A HD3    1 c 
ATOM   1788 H HE2    . LYS A 1 118 ? -17.603 -13.306 25.64   1    51.02  ? 1126 LYS A HE2    1 c 
ATOM   1789 H HE3    . LYS A 1 118 ? -17.575 -12.169 24.288  1    51.02  ? 1126 LYS A HE3    1 c 
ATOM   1790 H HZ1    . LYS A 1 118 ? -19.42  -14.56  24.271  1    46.289 ? 1126 LYS A HZ1    1 ? 
ATOM   1791 H HZ2    . LYS A 1 118 ? -19.768 -13.078 24.947  1    51.057 ? 1126 LYS A HZ2    1 ? 
ATOM   1792 H HZ3    . LYS A 1 118 ? -19.443 -13.183 23.326  1    47.848 ? 1126 LYS A HZ3    1 ? 
ATOM   1793 N N      . GLU A 1 119 ? -11.148 -15.318 23.603  1    33.345 ? 1127 GLU A N      1 ? 
ATOM   1794 C CA     . GLU A 1 119 ? -10.061 -16.303 23.7    1    29.474 ? 1127 GLU A CA     1 ? 
ATOM   1795 C C      . GLU A 1 119 ? -10.677 -17.66  24.036  1    32.358 ? 1127 GLU A C      1 ? 
ATOM   1796 O O      . GLU A 1 119 ? -11.902 -17.707 24.218  1    32.021 ? 1127 GLU A O      1 ? 
ATOM   1797 C CB     . GLU A 1 119 ? -9.073  -15.798 24.765  1    31.905 ? 1127 GLU A CB     1 ? 
ATOM   1798 C CG     . GLU A 1 119 ? -8.588  -14.362 24.514  1    36.737 ? 1127 GLU A CG     1 ? 
ATOM   1799 C CD     . GLU A 1 119 ? -7.467  -13.809 25.407  1    40.986 ? 1127 GLU A CD     1 ? 
ATOM   1800 O OE1    . GLU A 1 119 ? -7.213  -12.577 25.344  1    39.24  ? 1127 GLU A OE1    1 ? 
ATOM   1801 O OE2    . GLU A 1 119 ? -6.81   -14.596 26.135  1    41.769 ? 1127 GLU A OE2    1 ? 
ATOM   1802 H H      . GLU A 1 119 ? -11.338 -14.714 24.422  1    31.948 ? 1127 GLU A H      1 ? 
ATOM   1803 H HA     . GLU A 1 119 ? -9.563  -16.366 22.733  1    31.033 ? 1127 GLU A HA     1 c 
ATOM   1804 H HB2    . GLU A 1 119 ? -9.551  -15.854 25.744  1    32.431 ? 1127 GLU A HB2    1 c 
ATOM   1805 H HB3    . GLU A 1 119 ? -8.207  -16.463 24.781  1    32.356 ? 1127 GLU A HB3    1 c 
ATOM   1806 H HG2    . GLU A 1 119 ? -8.251  -14.293 23.478  1    36.495 ? 1127 GLU A HG2    1 c 
ATOM   1807 H HG3    . GLU A 1 119 ? -9.445  -13.692 24.605  1    36.522 ? 1127 GLU A HG3    1 c 
ATOM   1808 N N      . ASP A 1 120 ? -9.87   -18.731 24.229  1    29.055 ? 1128 ASP A N      1 ? 
ATOM   1809 C CA     . ASP A 1 120 ? -10.393 -20.021 24.642  1    31.533 ? 1128 ASP A CA     1 ? 
ATOM   1810 C C      . ASP A 1 120 ? -9.163  -20.889 24.932  1    32.756 ? 1128 ASP A C      1 ? 
ATOM   1811 O O      . ASP A 1 120 ? -8.443  -21.279 23.994  1    28.047 ? 1128 ASP A O      1 ? 
ATOM   1812 C CB     . ASP A 1 120 ? -11.369 -20.583 23.623  1    25.514 ? 1128 ASP A CB     1 ? 
ATOM   1813 C CG     . ASP A 1 120 ? -11.652 -22.071 23.748  1    30.378 ? 1128 ASP A CG     1 ? 
ATOM   1814 O OD1    . ASP A 1 120 ? -11.045 -22.759 24.623  1    24.908 ? 1128 ASP A OD1    1 ? 
ATOM   1815 O OD2    . ASP A 1 120 ? -12.506 -22.54  22.978  1    34.05  ? 1128 ASP A OD2    1 ? 
ATOM   1816 H H      . ASP A 1 120 ? -8.836  -18.646 24.203  1    33.618 ? 1128 ASP A H      1 ? 
ATOM   1817 H HA     . ASP A 1 120 ? -10.948 -19.876 25.57   1    30.11  ? 1128 ASP A HA     1 c 
ATOM   1818 H HB2    . ASP A 1 120 ? -12.32  -20.055 23.702  1    27.794 ? 1128 ASP A HB2    1 c 
ATOM   1819 H HB3    . ASP A 1 120 ? -10.969 -20.4   22.623  1    27.777 ? 1128 ASP A HB3    1 c 
ATOM   1820 N N      . PRO A 1 121 ? -8.906  -21.213 26.224  1    28.638 ? 1129 PRO A N      1 ? 
ATOM   1821 C CA     . PRO A 1 121 ? -7.613  -21.749 26.618  1    32.185 ? 1129 PRO A CA     1 ? 
ATOM   1822 C C      . PRO A 1 121 ? -7.379  -23.063 25.9    1    36.585 ? 1129 PRO A C      1 ? 
ATOM   1823 O O      . PRO A 1 121 ? -6.24   -23.459 25.632  1    38.671 ? 1129 PRO A O      1 ? 
ATOM   1824 C CB     . PRO A 1 121 ? -7.706  -22.043 28.144  1    31.572 ? 1129 PRO A CB     1 ? 
ATOM   1825 C CG     . PRO A 1 121 ? -9.148  -21.69  28.603  1    29.301 ? 1129 PRO A CG     1 ? 
ATOM   1826 C CD     . PRO A 1 121 ? -9.879  -21.111 27.35   1    33.654 ? 1129 PRO A CD     1 ? 
ATOM   1827 H HA     . PRO A 1 121 ? -6.816  -21.037 26.394  1    32.109 ? 1129 PRO A HA     1 c 
ATOM   1828 H HB2    . PRO A 1 121 ? -7.491  -23.095 28.344  1    31.232 ? 1129 PRO A HB2    1 c 
ATOM   1829 H HB3    . PRO A 1 121 ? -6.977  -21.444 28.692  1    31.206 ? 1129 PRO A HB3    1 c 
ATOM   1830 H HG2    . PRO A 1 121 ? -9.665  -22.58  28.966  1    30.658 ? 1129 PRO A HG2    1 c 
ATOM   1831 H HG3    . PRO A 1 121 ? -9.126  -20.95  29.405  1    30.658 ? 1129 PRO A HG3    1 c 
ATOM   1832 H HD2    . PRO A 1 121 ? -10.767 -21.694 27.119  1    31.532 ? 1129 PRO A HD2    1 c 
ATOM   1833 H HD3    . PRO A 1 121 ? -10.168 -20.071 27.512  1    31.528 ? 1129 PRO A HD3    1 c 
ATOM   1834 N N      . SER A 1 122 ? -8.506  -23.726 25.599  1    31.483 ? 1130 SER A N      1 ? 
ATOM   1835 C CA     . SER A 1 122 ? -8.447  -25.072 25.065  1    35.466 ? 1130 SER A CA     1 ? 
ATOM   1836 C C      . SER A 1 122 ? -7.924  -24.952 23.643  1    27.474 ? 1130 SER A C      1 ? 
ATOM   1837 O O      . SER A 1 122 ? -7.522  -25.969 23.072  1    35.701 ? 1130 SER A O      1 ? 
ATOM   1838 C CB     . SER A 1 122 ? -9.809  -25.774 25.119  1    39.811 ? 1130 SER A CB     1 ? 
ATOM   1839 O OG     . SER A 1 122 ? -10.731 -25.13  24.241  1    40.559 ? 1130 SER A OG     1 ? 
ATOM   1840 H H      . SER A 1 122 ? -9.425  -23.258 25.681  1    29.633 ? 1130 SER A H      1 ? 
ATOM   1841 H HA     . SER A 1 122 ? -7.73   -25.648 25.652  1    33.807 ? 1130 SER A HA     1 c 
ATOM   1842 H HB2    . SER A 1 122 ? -9.692  -26.819 24.825  1    39.012 ? 1130 SER A HB2    1 c 
ATOM   1843 H HB3    . SER A 1 122 ? -10.193 -25.743 26.141  1    39.012 ? 1130 SER A HB3    1 c 
ATOM   1844 H HG     . SER A 1 122 ? -10.773 -24.156 24.434  1    36.688 ? 1130 SER A HG     1 ? 
ATOM   1845 N N      . LYS A 1 123 ? -7.916  -23.716 23.086  1    27.044 ? 1131 LYS A N      1 ? 
ATOM   1846 C CA     . LYS A 1 123 ? -7.533  -23.526 21.686  1    31.397 ? 1131 LYS A CA     1 ? 
ATOM   1847 C C      . LYS A 1 123 ? -6.207  -22.774 21.528  1    30.907 ? 1131 LYS A C      1 ? 
ATOM   1848 O O      . LYS A 1 123 ? -5.763  -22.559 20.401  1    30.713 ? 1131 LYS A O      1 ? 
ATOM   1849 C CB     . LYS A 1 123 ? -8.617  -22.739 20.943  1    29.334 ? 1131 LYS A CB     1 ? 
ATOM   1850 C CG     . LYS A 1 123 ? -9.938  -23.496 20.883  1    30.319 ? 1131 LYS A CG     1 ? 
ATOM   1851 C CD     . LYS A 1 123 ? -11.069 -22.785 20.155  1    27.915 ? 1131 LYS A CD     1 ? 
ATOM   1852 C CE     . LYS A 1 123 ? -12.224 -23.734 19.929  1    26.12  ? 1131 LYS A CE     1 ? 
ATOM   1853 N NZ     . LYS A 1 123 ? -13.269 -23.061 19.148  1    26.806 ? 1131 LYS A NZ     1 ? 
ATOM   1854 H H      . LYS A 1 123 ? -8.179  -22.862 23.612  1    20.706 ? 1131 LYS A H      1 ? 
ATOM   1855 H HA     . LYS A 1 123 ? -7.433  -24.507 21.218  1    30.099 ? 1131 LYS A HA     1 c 
ATOM   1856 H HB2    . LYS A 1 123 ? -8.779  -21.784 21.446  1    29.985 ? 1131 LYS A HB2    1 c 
ATOM   1857 H HB3    . LYS A 1 123 ? -8.282  -22.534 19.924  1    29.988 ? 1131 LYS A HB3    1 c 
ATOM   1858 H HG2    . LYS A 1 123 ? -9.759  -24.457 20.397  1    29.561 ? 1131 LYS A HG2    1 c 
ATOM   1859 H HG3    . LYS A 1 123 ? -10.258 -23.705 21.906  1    29.551 ? 1131 LYS A HG3    1 c 
ATOM   1860 H HD2    . LYS A 1 123 ? -11.41  -21.934 20.749  1    28.041 ? 1131 LYS A HD2    1 c 
ATOM   1861 H HD3    . LYS A 1 123 ? -10.709 -22.417 19.192  1    28.015 ? 1131 LYS A HD3    1 c 
ATOM   1862 H HE2    . LYS A 1 123 ? -11.881 -24.617 19.386  1    26.682 ? 1131 LYS A HE2    1 c 
ATOM   1863 H HE3    . LYS A 1 123 ? -12.638 -24.054 20.887  1    26.694 ? 1131 LYS A HE3    1 c 
ATOM   1864 H HZ1    . LYS A 1 123 ? -14.06  -23.706 19.213  1    22.509 ? 1131 LYS A HZ1    1 ? 
ATOM   1865 H HZ2    . LYS A 1 123 ? -13.473 -22.094 19.546  1    21.788 ? 1131 LYS A HZ2    1 ? 
ATOM   1866 H HZ3    . LYS A 1 123 ? -12.971 -22.935 18.169  1    23.823 ? 1131 LYS A HZ3    1 ? 
ATOM   1867 N N      . ASN A 1 124 ? -5.568  -22.377 22.634  1    27.851 ? 1132 ASN A N      1 ? 
ATOM   1868 C CA     . ASN A 1 124 ? -4.244  -21.783 22.562  1    26.478 ? 1132 ASN A CA     1 ? 
ATOM   1869 C C      . ASN A 1 124 ? -3.217  -22.828 22.112  1    19.847 ? 1132 ASN A C      1 ? 
ATOM   1870 O O      . ASN A 1 124 ? -3.393  -24.016 22.33   1    19.325 ? 1132 ASN A O      1 ? 
ATOM   1871 C CB     . ASN A 1 124 ? -3.844  -21.228 23.914  1    28.554 ? 1132 ASN A CB     1 ? 
ATOM   1872 C CG     . ASN A 1 124 ? -4.405  -19.855 24.181  1    33.948 ? 1132 ASN A CG     1 ? 
ATOM   1873 O OD1    . ASN A 1 124 ? -4.99   -19.204 23.299  1    35.954 ? 1132 ASN A OD1    1 ? 
ATOM   1874 N ND2    . ASN A 1 124 ? -4.215  -19.415 25.414  1    35.382 ? 1132 ASN A ND2    1 ? 
ATOM   1875 H H      . ASN A 1 124 ? -5.994  -22.514 23.564  1    27.512 ? 1132 ASN A H      1 ? 
ATOM   1876 H HA     . ASN A 1 124 ? -4.263  -20.961 21.843  1    25.805 ? 1132 ASN A HA     1 c 
ATOM   1877 H HB2    . ASN A 1 124 ? -4.19   -21.91  24.693  1    29.149 ? 1132 ASN A HB2    1 c 
ATOM   1878 H HB3    . ASN A 1 124 ? -2.754  -21.182 23.97   1    29.027 ? 1132 ASN A HB3    1 c 
ATOM   1879 H HD21   . ASN A 1 124 ? -4.397  -18.44  25.654  1    33.461 ? 1132 ASN A HD21   1 ? 
ATOM   1880 H HD22   . ASN A 1 124 ? -3.822  -20.084 26.09   1    31.317 ? 1132 ASN A HD22   1 ? 
ATOM   1881 N N      . GLY A 1 125 ? -2.083  -22.372 21.549  1    21.415 ? 1133 GLY A N      1 ? 
ATOM   1882 C CA     . GLY A 1 125 ? -1.001  -23.307 21.281  1    19.747 ? 1133 GLY A CA     1 ? 
ATOM   1883 C C      . GLY A 1 125 ? -0.452  -23.818 22.613  1    18.78  ? 1133 GLY A C      1 ? 
ATOM   1884 O O      . GLY A 1 125 ? -0.177  -23.008 23.505  1    18.784 ? 1133 GLY A O      1 ? 
ATOM   1885 H H      . GLY A 1 125 ? -1.92   -21.354 21.427  1    19.933 ? 1133 GLY A H      1 ? 
ATOM   1886 H HA2    . GLY A 1 125 ? -1.374  -24.141 20.682  1    19.884 ? 1133 GLY A HA2    1 c 
ATOM   1887 H HA3    . GLY A 1 125 ? -0.215  -22.8   20.721  1    19.832 ? 1133 GLY A HA3    1 c 
ATOM   1888 N N      . VAL A 1 126 ? -0.306  -25.134 22.752  1    18.303 ? 1134 VAL A N      1 ? 
ATOM   1889 C CA     . VAL A 1 126 ? 0.15    -25.739 23.991  1    21.366 ? 1134 VAL A CA     1 ? 
ATOM   1890 C C      . VAL A 1 126 ? 1.615   -25.409 24.274  1    18.419 ? 1134 VAL A C      1 ? 
ATOM   1891 O O      . VAL A 1 126 ? 1.93    -24.844 25.324  1    15.623 ? 1134 VAL A O      1 ? 
ATOM   1892 C CB     . VAL A 1 126 ? -0.121  -27.249 23.909  1    25.207 ? 1134 VAL A CB     1 ? 
ATOM   1893 C CG1    . VAL A 1 126 ? 0.549   -28.034 25.024  1    26.573 ? 1134 VAL A CG1    1 ? 
ATOM   1894 C CG2    . VAL A 1 126 ? -1.607  -27.528 23.842  1    28.242 ? 1134 VAL A CG2    1 ? 
ATOM   1895 H H      . VAL A 1 126 ? -0.515  -25.766 21.962  1    19.661 ? 1134 VAL A H      1 ? 
ATOM   1896 H HA     . VAL A 1 126 ? -0.452  -25.331 24.805  1    20.807 ? 1134 VAL A HA     1 c 
ATOM   1897 H HB     . VAL A 1 126 ? 0.313   -27.596 22.968  1    25.219 ? 1134 VAL A HB     1 c 
ATOM   1898 H HG11   . VAL A 1 126 ? 1.634   -27.974 24.914  1    26.11  ? 1134 VAL A HG11   1 c 
ATOM   1899 H HG12   . VAL A 1 126 ? 0.259   -27.616 25.99   1    26.15  ? 1134 VAL A HG12   1 c 
ATOM   1900 H HG13   . VAL A 1 126 ? 0.238   -29.079 24.972  1    26.08  ? 1134 VAL A HG13   1 c 
ATOM   1901 H HG21   . VAL A 1 126 ? -1.774  -28.606 23.795  1    27.336 ? 1134 VAL A HG21   1 c 
ATOM   1902 H HG22   . VAL A 1 126 ? -2.094  -27.123 24.731  1    27.457 ? 1134 VAL A HG22   1 c 
ATOM   1903 H HG23   . VAL A 1 126 ? -2.028  -27.057 22.951  1    27.144 ? 1134 VAL A HG23   1 c 
ATOM   1904 N N      . CYS A 1 127 ? 2.514   -25.791 23.365  1    17.772 ? 1135 CYS A N      1 ? 
ATOM   1905 C CA     . CYS A 1 127 ? 3.935   -25.71  23.694  1    17.435 ? 1135 CYS A CA     1 ? 
ATOM   1906 C C      . CYS A 1 127 ? 4.423   -24.262 23.746  1    17.531 ? 1135 CYS A C      1 ? 
ATOM   1907 O O      . CYS A 1 127 ? 5.248   -23.916 24.601  1    16.467 ? 1135 CYS A O      1 ? 
ATOM   1908 C CB     . CYS A 1 127 ? 4.776   -26.558 22.755  1    17.525 ? 1135 CYS A CB     1 ? 
ATOM   1909 S SG     . CYS A 1 127 ? 6.391   -26.987 23.456  1    16.646 ? 1135 CYS A SG     1 ? 
ATOM   1910 H H      . CYS A 1 127 ? 2.225   -26.185 22.456  1    19.542 ? 1135 CYS A H      1 ? 
ATOM   1911 H HA     . CYS A 1 127 ? 4.06    -26.137 24.692  1    17.52  ? 1135 CYS A HA     1 c 
ATOM   1912 H HB2    . CYS A 1 127 ? 4.239   -27.48  22.524  1    17.342 ? 1135 CYS A HB2    1 c 
ATOM   1913 H HB3    . CYS A 1 127 ? 4.932   -26.014 21.821  1    17.346 ? 1135 CYS A HB3    1 c 
ATOM   1914 H HG     . CYS A 1 127 ? 6.811   -25.755 23.718  1    17.591 ? 1135 CYS A HG     1 ? 
ATOM   1915 N N      . SER A 1 128 ? 3.934   -23.409 22.845  1    16.209 ? 1136 SER A N      1 ? 
ATOM   1916 C CA     . SER A 1 128 ? 4.424   -22.035 22.836  1    15.473 ? 1136 SER A CA     1 ? 
ATOM   1917 C C      . SER A 1 128 ? 4.014   -21.301 24.105  1    15.302 ? 1136 SER A C      1 ? 
ATOM   1918 O O      . SER A 1 128 ? 4.807   -20.548 24.683  1    15.507 ? 1136 SER A O      1 ? 
ATOM   1919 C CB     . SER A 1 128 ? 3.964   -21.295 21.582  1    17.199 ? 1136 SER A CB     1 ? 
ATOM   1920 O OG     . SER A 1 128 ? 2.544   -21.217 21.506  1    18.468 ? 1136 SER A OG     1 ? 
ATOM   1921 H H      . SER A 1 128 ? 3.185   -23.686 22.182  1    16.253 ? 1136 SER A H      1 ? 
ATOM   1922 H HA     . SER A 1 128 ? 5.515   -22.075 22.817  1    15.878 ? 1136 SER A HA     1 c 
ATOM   1923 H HB2    . SER A 1 128 ? 4.38    -20.286 21.591  1    17.094 ? 1136 SER A HB2    1 c 
ATOM   1924 H HB3    . SER A 1 128 ? 4.346   -21.811 20.699  1    17.095 ? 1136 SER A HB3    1 c 
ATOM   1925 H HG     . SER A 1 128 ? 2.293   -22.075 21.126  1    17.584 ? 1136 SER A HG     1 ? 
ATOM   1926 N N      . ASN A 1 129 ? 2.771   -21.509 24.546  1    16.193 ? 1137 ASN A N      1 ? 
ATOM   1927 C CA     . ASN A 1 129 ? 2.359   -20.906 25.807  1    15.738 ? 1137 ASN A CA     1 ? 
ATOM   1928 C C      . ASN A 1 129 ? 3.057   -21.537 27.006  1    15.156 ? 1137 ASN A C      1 ? 
ATOM   1929 O O      . ASN A 1 129 ? 3.424   -20.828 27.944  1    16.015 ? 1137 ASN A O      1 ? 
ATOM   1930 C CB     . ASN A 1 129 ? 0.84    -20.908 25.921  1    17.523 ? 1137 ASN A CB     1 ? 
ATOM   1931 C CG     . ASN A 1 129 ? 0.223   -19.919 24.965  1    18.575 ? 1137 ASN A CG     1 ? 
ATOM   1932 O OD1    . ASN A 1 129 ? 0.297   -18.709 25.186  1    18.997 ? 1137 ASN A OD1    1 ? 
ATOM   1933 N ND2    . ASN A 1 129 ? -0.277  -20.379 23.849  1    17.628 ? 1137 ASN A ND2    1 ? 
ATOM   1934 H H      . ASN A 1 129 ? 2.118   -22.126 24.032  1    15.784 ? 1137 ASN A H      1 ? 
ATOM   1935 H HA     . ASN A 1 129 ? 2.664   -19.858 25.776  1    16.021 ? 1137 ASN A HA     1 c 
ATOM   1936 H HB2    . ASN A 1 129 ? 0.461   -21.908 25.701  1    17.348 ? 1137 ASN A HB2    1 c 
ATOM   1937 H HB3    . ASN A 1 129 ? 0.553   -20.65  26.942  1    17.341 ? 1137 ASN A HB3    1 c 
ATOM   1938 H HD21   . ASN A 1 129 ? -0.451  -19.595 23.215  1    20.795 ? 1137 ASN A HD21   1 ? 
ATOM   1939 H HD22   . ASN A 1 129 ? -0.304  -21.358 23.571  1    18.705 ? 1137 ASN A HD22   1 ? 
ATOM   1940 N N      . PHE A 1 130 ? 3.239   -22.86  26.991  1    15.667 ? 1138 PHE A N      1 ? 
ATOM   1941 C CA     . PHE A 1 130 ? 3.987   -23.528 28.048  1    15.73  ? 1138 PHE A CA     1 ? 
ATOM   1942 C C      . PHE A 1 130 ? 5.361   -22.883 28.217  1    16.363 ? 1138 PHE A C      1 ? 
ATOM   1943 O O      . PHE A 1 130 ? 5.779   -22.551 29.334  1    14.956 ? 1138 PHE A O      1 ? 
ATOM   1944 C CB     . PHE A 1 130 ? 4.121   -25.008 27.694  1    17.058 ? 1138 PHE A CB     1 ? 
ATOM   1945 C CG     . PHE A 1 130 ? 5.102   -25.764 28.556  1    16.439 ? 1138 PHE A CG     1 ? 
ATOM   1946 C CD1    . PHE A 1 130 ? 4.887   -25.927 29.93   1    16.97  ? 1138 PHE A CD1    1 ? 
ATOM   1947 C CD2    . PHE A 1 130 ? 6.24    -26.31  27.994  1    15.893 ? 1138 PHE A CD2    1 ? 
ATOM   1948 C CE1    . PHE A 1 130 ? 5.799   -26.609 30.705  1    17.62  ? 1138 PHE A CE1    1 ? 
ATOM   1949 C CE2    . PHE A 1 130 ? 7.137   -27.019 28.761  1    15.588 ? 1138 PHE A CE2    1 ? 
ATOM   1950 C CZ     . PHE A 1 130 ? 6.917   -27.19  30.115  1    17.889 ? 1138 PHE A CZ     1 ? 
ATOM   1951 H H      . PHE A 1 130 ? 2.838   -23.426 26.225  1    18.729 ? 1138 PHE A H      1 ? 
ATOM   1952 H HA     . PHE A 1 130 ? 3.437   -23.436 28.983  1    16.133 ? 1138 PHE A HA     1 c 
ATOM   1953 H HB2    . PHE A 1 130 ? 3.138   -25.475 27.786  1    16.623 ? 1138 PHE A HB2    1 c 
ATOM   1954 H HB3    . PHE A 1 130 ? 4.432   -25.089 26.651  1    16.623 ? 1138 PHE A HB3    1 c 
ATOM   1955 H HD1    . PHE A 1 130 ? 4.005   -25.493 30.39   1    16.996 ? 1138 PHE A HD1    1 c 
ATOM   1956 H HD2    . PHE A 1 130 ? 6.411   -26.205 26.928  1    15.975 ? 1138 PHE A HD2    1 c 
ATOM   1957 H HE1    . PHE A 1 130 ? 5.616   -26.739 31.766  1    17.502 ? 1138 PHE A HE1    1 c 
ATOM   1958 H HE2    . PHE A 1 130 ? 8.02    -27.448 28.298  1    16.155 ? 1138 PHE A HE2    1 c 
ATOM   1959 H HZ     . PHE A 1 130 ? 7.639   -27.726 30.722  1    17.28  ? 1138 PHE A HZ     1 c 
ATOM   1960 N N      . LEU A 1 131 ? 6.054   -22.669 27.098  1    16.753 ? 1139 LEU A N      1 ? 
ATOM   1961 C CA     . LEU A 1 131 ? 7.395   -22.094 27.139  1    17.768 ? 1139 LEU A CA     1 ? 
ATOM   1962 C C      . LEU A 1 131 ? 7.368   -20.643 27.621  1    13.949 ? 1139 LEU A C      1 ? 
ATOM   1963 O O      . LEU A 1 131 ? 8.092   -20.276 28.555  1    14.616 ? 1139 LEU A O      1 ? 
ATOM   1964 C CB     . LEU A 1 131 ? 8.066   -22.235 25.773  1    17.105 ? 1139 LEU A CB     1 ? 
ATOM   1965 C CG     . LEU A 1 131 ? 8.522   -23.652 25.436  1    16.806 ? 1139 LEU A CG     1 ? 
ATOM   1966 C CD1    . LEU A 1 131 ? 8.877   -23.79  23.974  1    18.438 ? 1139 LEU A CD1    1 ? 
ATOM   1967 C CD2    . LEU A 1 131 ? 9.685   -24.081 26.291  1    16.628 ? 1139 LEU A CD2    1 ? 
ATOM   1968 H H      . LEU A 1 131 ? 5.636   -22.913 26.181  1    16.626 ? 1139 LEU A H      1 ? 
ATOM   1969 H HA     . LEU A 1 131 ? 7.971   -22.667 27.867  1    16.71  ? 1139 LEU A HA     1 c 
ATOM   1970 H HB2    . LEU A 1 131 ? 7.36    -21.906 25.007  1    17.181 ? 1139 LEU A HB2    1 c 
ATOM   1971 H HB3    . LEU A 1 131 ? 8.935   -21.575 25.747  1    17.181 ? 1139 LEU A HB3    1 c 
ATOM   1972 H HG     . LEU A 1 131 ? 7.691   -24.33  25.641  1    17.112 ? 1139 LEU A HG     1 c 
ATOM   1973 H HD11   . LEU A 1 131 ? 9.688   -23.101 23.728  1    17.965 ? 1139 LEU A HD11   1 c 
ATOM   1974 H HD12   . LEU A 1 131 ? 9.198   -24.814 23.771  1    17.961 ? 1139 LEU A HD12   1 c 
ATOM   1975 H HD13   . LEU A 1 131 ? 8.004   -23.556 23.362  1    17.943 ? 1139 LEU A HD13   1 c 
ATOM   1976 H HD21   . LEU A 1 131 ? 10.512  -23.379 26.162  1    16.68  ? 1139 LEU A HD21   1 c 
ATOM   1977 H HD22   . LEU A 1 131 ? 9.383   -24.096 27.34   1    16.68  ? 1139 LEU A HD22   1 c 
ATOM   1978 H HD23   . LEU A 1 131 ? 10.008  -25.081 25.993  1    16.686 ? 1139 LEU A HD23   1 c 
ATOM   1979 N N      . CYS A 1 132 ? 6.496   -19.812 27.035  1    15.771 ? 1140 CYS A N      1 ? 
ATOM   1980 C CA     . CYS A 1 132 ? 6.478   -18.415 27.418  1    15.691 ? 1140 CYS A CA     1 ? 
ATOM   1981 C C      . CYS A 1 132 ? 5.941   -18.192 28.839  1    17.209 ? 1140 CYS A C      1 ? 
ATOM   1982 O O      . CYS A 1 132 ? 6.215   -17.142 29.427  1    16.744 ? 1140 CYS A O      1 ? 
ATOM   1983 C CB     . CYS A 1 132 ? 5.616   -17.581 26.491  1    18.472 ? 1140 CYS A CB     1 ? 
ATOM   1984 S SG     . CYS A 1 132 ? 6.436   -17.124 24.941  1    18.275 ? 1140 CYS A SG     1 ? 
ATOM   1985 H H      . CYS A 1 132 ? 5.762   -20.158 26.384  1    15.61  ? 1140 CYS A H      1 ? 
ATOM   1986 H HA     . CYS A 1 132 ? 7.502   -18.045 27.379  1    16.42  ? 1140 CYS A HA     1 c 
ATOM   1987 H HB2    . CYS A 1 132 ? 4.709   -18.139 26.25   1    17.758 ? 1140 CYS A HB2    1 c 
ATOM   1988 H HB3    . CYS A 1 132 ? 5.319   -16.666 27.007  1    17.756 ? 1140 CYS A HB3    1 c 
ATOM   1989 N N      . ASN A 1 133 ? 5.19    -19.152 29.386  1    14.924 ? 1141 ASN A N      1 ? 
ATOM   1990 C CA     . ASN A 1 133 ? 4.717   -19.124 30.769  1    16.614 ? 1141 ASN A CA     1 ? 
ATOM   1991 C C      . ASN A 1 133 ? 5.732   -19.679 31.764  1    16.948 ? 1141 ASN A C      1 ? 
ATOM   1992 O O      . ASN A 1 133 ? 5.48    -19.652 32.974  1    16.73  ? 1141 ASN A O      1 ? 
ATOM   1993 C CB     . ASN A 1 133 ? 3.428   -19.936 30.897  1    18.069 ? 1141 ASN A CB     1 ? 
ATOM   1994 C CG     . ASN A 1 133 ? 2.244   -19.232 30.289  1    20.161 ? 1141 ASN A CG     1 ? 
ATOM   1995 O OD1    . ASN A 1 133 ? 2.237   -18.01  30.138  1    19.928 ? 1141 ASN A OD1    1 ? 
ATOM   1996 N ND2    . ASN A 1 133 ? 1.225   -19.997 29.943  1    19.766 ? 1141 ASN A ND2    1 ? 
ATOM   1997 H H      . ASN A 1 133 ? 4.871   -19.932 28.784  1    15.589 ? 1141 ASN A H      1 ? 
ATOM   1998 H HA     . ASN A 1 133 ? 4.491   -18.09  31.037  1    16.607 ? 1141 ASN A HA     1 c 
ATOM   1999 H HB2    . ASN A 1 133 ? 3.562   -20.902 30.406  1    18.161 ? 1141 ASN A HB2    1 c 
ATOM   2000 H HB3    . ASN A 1 133 ? 3.226   -20.122 31.954  1    18.166 ? 1141 ASN A HB3    1 c 
ATOM   2001 H HD21   . ASN A 1 133 ? 0.448   -19.593 29.467  1    19.238 ? 1141 ASN A HD21   1 ? 
ATOM   2002 H HD22   . ASN A 1 133 ? 1.207   -20.978 30.137  1    18.94  ? 1141 ASN A HD22   1 ? 
ATOM   2003 N N      . SER A 1 134 ? 6.872   -20.166 31.291  1    15.016 ? 1142 SER A N      1 ? 
ATOM   2004 C CA     . SER A 1 134 ? 7.818   -20.834 32.17   1    17.147 ? 1142 SER A CA     1 ? 
ATOM   2005 C C      . SER A 1 134 ? 8.563   -19.819 33.039  1    17.802 ? 1142 SER A C      1 ? 
ATOM   2006 O O      . SER A 1 134 ? 8.623   -18.621 32.744  1    16.453 ? 1142 SER A O      1 ? 
ATOM   2007 C CB     . SER A 1 134 ? 8.814   -21.645 31.356  1    15.636 ? 1142 SER A CB     1 ? 
ATOM   2008 O OG     . SER A 1 134 ? 8.192   -22.781 30.765  1    17.076 ? 1142 SER A OG     1 ? 
ATOM   2009 H H      . SER A 1 134 ? 7.069   -20.124 30.273  1    16.585 ? 1142 SER A H      1 ? 
ATOM   2010 H HA     . SER A 1 134 ? 7.264   -21.511 32.824  1    16.561 ? 1142 SER A HA     1 c 
ATOM   2011 H HB2    . SER A 1 134 ? 9.241   -21.015 30.575  1    16.265 ? 1142 SER A HB2    1 c 
ATOM   2012 H HB3    . SER A 1 134 ? 9.626   -21.976 32.007  1    16.275 ? 1142 SER A HB3    1 c 
ATOM   2013 H HG     . SER A 1 134 ? 7.454   -22.517 30.192  1    16.048 ? 1142 SER A HG     1 ? 
ATOM   2014 N N      . LYS A 1 135 ? 9.16    -20.321 34.117  1    16.962 ? 1143 LYS A N      1 ? 
ATOM   2015 C CA     . LYS A 1 135 ? 9.834   -19.498 35.105  1    17.227 ? 1143 LYS A CA     1 ? 
ATOM   2016 C C      . LYS A 1 135 ? 11.14   -20.19  35.482  1    16.557 ? 1143 LYS A C      1 ? 
ATOM   2017 O O      . LYS A 1 135 ? 11.262  -21.413 35.345  1    14.169 ? 1143 LYS A O      1 ? 
ATOM   2018 C CB     . LYS A 1 135 ? 8.981   -19.348 36.36   1    17.571 ? 1143 LYS A CB     1 ? 
ATOM   2019 C CG     . LYS A 1 135 ? 7.683   -18.597 36.138  1    19.979 ? 1143 LYS A CG     1 ? 
ATOM   2020 C CD     . LYS A 1 135 ? 7.892   -17.12  35.874  1    23.096 ? 1143 LYS A CD     1 ? 
ATOM   2021 C CE     . LYS A 1 135 ? 6.56    -16.411 35.781  1    28.108 ? 1143 LYS A CE     1 ? 
ATOM   2022 N NZ     . LYS A 1 135 ? 6.675   -14.967 35.493  1    28.445 ? 1143 LYS A NZ     1 ? 
ATOM   2023 H H      . LYS A 1 135 ? 9.128   -21.344 34.274  1    17.46  ? 1143 LYS A H      1 ? 
ATOM   2024 H HA     . LYS A 1 135 ? 10.048  -18.521 34.669  1    17.121 ? 1143 LYS A HA     1 c 
ATOM   2025 H HB2    . LYS A 1 135 ? 8.747   -20.342 36.747  1    17.997 ? 1143 LYS A HB2    1 c 
ATOM   2026 H HB3    . LYS A 1 135 ? 9.562   -18.822 37.121  1    17.997 ? 1143 LYS A HB3    1 c 
ATOM   2027 H HG2    . LYS A 1 135 ? 7.16    -19.043 35.289  1    20.037 ? 1143 LYS A HG2    1 c 
ATOM   2028 H HG3    . LYS A 1 135 ? 7.054   -18.717 37.022  1    20.046 ? 1143 LYS A HG3    1 c 
ATOM   2029 H HD2    . LYS A 1 135 ? 8.479   -16.684 36.685  1    23.361 ? 1143 LYS A HD2    1 c 
ATOM   2030 H HD3    . LYS A 1 135 ? 8.438   -16.99  34.937  1    23.361 ? 1143 LYS A HD3    1 c 
ATOM   2031 H HE2    . LYS A 1 135 ? 5.963   -16.878 34.995  1    27.121 ? 1143 LYS A HE2    1 c 
ATOM   2032 H HE3    . LYS A 1 135 ? 6.024   -16.536 36.724  1    27.024 ? 1143 LYS A HE3    1 c 
ATOM   2033 H HZ1    . LYS A 1 135 ? 5.765   -14.644 35.156  1    28.003 ? 1143 LYS A HZ1    1 ? 
ATOM   2034 H HZ2    . LYS A 1 135 ? 6.939   -14.435 36.321  1    27.212 ? 1143 LYS A HZ2    1 ? 
ATOM   2035 H HZ3    . LYS A 1 135 ? 7.373   -14.815 34.758  1    27.522 ? 1143 LYS A HZ3    1 ? 
ATOM   2036 N N      . PRO A 1 136 ? 12.133  -19.432 35.978  1    17.458 ? 1144 PRO A N      1 ? 
ATOM   2037 C CA     . PRO A 1 136 ? 13.377  -20.045 36.428  1    16.774 ? 1144 PRO A CA     1 ? 
ATOM   2038 C C      . PRO A 1 136 ? 13.12   -21.236 37.342  1    15.829 ? 1144 PRO A C      1 ? 
ATOM   2039 O O      . PRO A 1 136 ? 12.293  -21.178 38.256  1    16.259 ? 1144 PRO A O      1 ? 
ATOM   2040 C CB     . PRO A 1 136 ? 14.083  -18.905 37.168  1    16.442 ? 1144 PRO A CB     1 ? 
ATOM   2041 C CG     . PRO A 1 136 ? 13.561  -17.664 36.495  1    17.285 ? 1144 PRO A CG     1 ? 
ATOM   2042 C CD     . PRO A 1 136 ? 12.126  -17.974 36.157  1    17.937 ? 1144 PRO A CD     1 ? 
ATOM   2043 H HA     . PRO A 1 136 ? 13.968  -20.358 35.565  1    16.657 ? 1144 PRO A HA     1 c 
ATOM   2044 H HB2    . PRO A 1 136 ? 13.831  -18.912 38.23   1    16.754 ? 1144 PRO A HB2    1 c 
ATOM   2045 H HB3    . PRO A 1 136 ? 15.167  -18.982 37.059  1    16.705 ? 1144 PRO A HB3    1 c 
ATOM   2046 H HG2    . PRO A 1 136 ? 13.621  -16.805 37.166  1    17.236 ? 1144 PRO A HG2    1 c 
ATOM   2047 H HG3    . PRO A 1 136 ? 14.13   -17.444 35.59   1    17.236 ? 1144 PRO A HG3    1 c 
ATOM   2048 H HD2    . PRO A 1 136 ? 11.453  -17.686 36.967  1    17.766 ? 1144 PRO A HD2    1 c 
ATOM   2049 H HD3    . PRO A 1 136 ? 11.818  -17.475 35.237  1    17.825 ? 1144 PRO A HD3    1 c 
ATOM   2050 N N      . GLY A 1 137 ? 13.845  -22.322 37.09   1    15.194 ? 1145 GLY A N      1 ? 
ATOM   2051 C CA     . GLY A 1 137 ? 13.722  -23.523 37.866  1    15.441 ? 1145 GLY A CA     1 ? 
ATOM   2052 C C      . GLY A 1 137 ? 12.732  -24.54  37.309  1    16.835 ? 1145 GLY A C      1 ? 
ATOM   2053 O O      . GLY A 1 137 ? 12.791  -25.705 37.692  1    16.474 ? 1145 GLY A O      1 ? 
ATOM   2054 H H      . GLY A 1 137 ? 14.445  -22.32  36.253  1    16.712 ? 1145 GLY A H      1 ? 
ATOM   2055 H HA2    . GLY A 1 137 ? 14.707  -23.992 37.929  1    15.676 ? 1145 GLY A HA2    1 c 
ATOM   2056 H HA3    . GLY A 1 137 ? 13.426  -23.258 38.883  1    15.695 ? 1145 GLY A HA3    1 c 
ATOM   2057 N N      . ASP A 1 138 ? 11.821  -24.13  36.421  1    16.391 ? 1146 ASP A N      1 ? 
ATOM   2058 C CA     . ASP A 1 138 ? 10.928  -25.094 35.799  1    16.562 ? 1146 ASP A CA     1 ? 
ATOM   2059 C C      . ASP A 1 138 ? 11.704  -26.11  34.973  1    17.04  ? 1146 ASP A C      1 ? 
ATOM   2060 O O      . ASP A 1 138 ? 12.76   -25.806 34.418  1    18.032 ? 1146 ASP A O      1 ? 
ATOM   2061 C CB     . ASP A 1 138 ? 9.89    -24.426 34.911  1    16.123 ? 1146 ASP A CB     1 ? 
ATOM   2062 C CG     . ASP A 1 138 ? 8.814   -23.63  35.644  1    16.146 ? 1146 ASP A CG     1 ? 
ATOM   2063 O OD1    . ASP A 1 138 ? 8.656   -23.776 36.885  1    16.589 ? 1146 ASP A OD1    1 ? 
ATOM   2064 O OD2    . ASP A 1 138 ? 8.084   -22.884 34.958  1    15.209 ? 1146 ASP A OD2    1 ? 
ATOM   2065 H H      . ASP A 1 138 ? 11.732  -23.122 36.191  1    16.921 ? 1146 ASP A H      1 ? 
ATOM   2066 H HA     . ASP A 1 138 ? 10.398  -25.627 36.592  1    16.534 ? 1146 ASP A HA     1 c 
ATOM   2067 H HB2    . ASP A 1 138 ? 10.404  -23.747 34.226  1    16.218 ? 1146 ASP A HB2    1 c 
ATOM   2068 H HB3    . ASP A 1 138 ? 9.396   -25.193 34.312  1    16.197 ? 1146 ASP A HB3    1 c 
ATOM   2069 N N      . LYS A 1 139 ? 11.14   -27.309 34.858  1    15.56  ? 1147 LYS A N      1 ? 
ATOM   2070 C CA     . LYS A 1 139 ? 11.737  -28.387 34.085  1    16.675 ? 1147 LYS A CA     1 ? 
ATOM   2071 C C      . LYS A 1 139 ? 11.087  -28.481 32.706  0.99 16.647 ? 1147 LYS A C      1 ? 
ATOM   2072 O O      . LYS A 1 139 ? 9.882   -28.277 32.562  1    16.228 ? 1147 LYS A O      1 ? 
ATOM   2073 C CB     . LYS A 1 139 ? 11.606  -29.729 34.813  1    17.515 ? 1147 LYS A CB     1 ? 
ATOM   2074 C CG     . LYS A 1 139 ? 12.172  -29.735 36.23   1    19.062 ? 1147 LYS A CG     1 ? 
ATOM   2075 C CD     . LYS A 1 139 ? 13.547  -29.141 36.311  1    20.91  ? 1147 LYS A CD     1 ? 
ATOM   2076 C CE     . LYS A 1 139 ? 14.18   -29.452 37.618  1    24.854 ? 1147 LYS A CE     1 ? 
ATOM   2077 N NZ     . LYS A 1 139 ? 15.455  -28.731 37.729  0.63 24.018 ? 1147 LYS A NZ     1 ? 
ATOM   2078 H H      . LYS A 1 139 ? 10.308  -27.485 35.446  1    17.574 ? 1147 LYS A H      1 ? 
ATOM   2079 H HA     . LYS A 1 139 ? 12.796  -28.166 33.953  1    16.626 ? 1147 LYS A HA     1 c 
ATOM   2080 H HB2    . LYS A 1 139 ? 10.55   -30.001 34.86   0.86 17.652 ? 1147 LYS A HB2    1 c 
ATOM   2081 H HB3    . LYS A 1 139 ? 12.121  -30.496 34.231  1    17.648 ? 1147 LYS A HB3    1 c 
ATOM   2082 H HG2    . LYS A 1 139 ? 11.499  -29.172 36.879  1    19.101 ? 1147 LYS A HG2    1 c 
ATOM   2083 H HG3    . LYS A 1 139 ? 12.204  -30.766 36.59   1    19.101 ? 1147 LYS A HG3    1 c 
ATOM   2084 H HD2    . LYS A 1 139 ? 14.165  -29.544 35.506  1    21.289 ? 1147 LYS A HD2    1 c 
ATOM   2085 H HD3    . LYS A 1 139 ? 13.483  -28.058 36.191  1    21.268 ? 1147 LYS A HD3    1 c 
ATOM   2086 H HE2    . LYS A 1 139 ? 13.52   -29.141 38.431  0.4  23.774 ? 1147 LYS A HE2    1 c 
ATOM   2087 H HE3    . LYS A 1 139 ? 14.354  -30.525 37.708  0.66 23.903 ? 1147 LYS A HE3    1 c 
ATOM   2088 H HZ1    . LYS A 1 139 ? 15.367  -27.759 38.016  1    23.328 ? 1147 LYS A HZ1    1 ? 
ATOM   2089 H HZ2    . LYS A 1 139 ? 16.002  -29.155 38.441  1    22.937 ? 1147 LYS A HZ2    1 ? 
ATOM   2090 H HZ3    . LYS A 1 139 ? 16.029  -28.781 36.894  1    23.654 ? 1147 LYS A HZ3    1 ? 
ATOM   2091 N N      . ILE A 1 140 ? 11.902  -28.812 31.705  1    17.183 ? 1148 ILE A N      1 ? 
ATOM   2092 C CA     . ILE A 1 140 ? 11.512  -28.906 30.299  1    17.834 ? 1148 ILE A CA     1 ? 
ATOM   2093 C C      . ILE A 1 140 ? 11.989  -30.269 29.803  0.85 18.24  ? 1148 ILE A C      1 ? 
ATOM   2094 O O      . ILE A 1 140 ? 13.15   -30.623 30.02   1    17.822 ? 1148 ILE A O      1 ? 
ATOM   2095 C CB     . ILE A 1 140 ? 12.219  -27.834 29.439  1    20.703 ? 1148 ILE A CB     1 ? 
ATOM   2096 C CG1    . ILE A 1 140 ? 11.928  -26.447 29.957  0.65 21.624 ? 1148 ILE A CG1    1 ? 
ATOM   2097 C CG2    . ILE A 1 140 ? 11.81   -27.927 27.966  0.58 19.14  ? 1148 ILE A CG2    1 ? 
ATOM   2098 C CD1    . ILE A 1 140 ? 10.461  -26.173 29.966  0.88 23.842 ? 1148 ILE A CD1    1 ? 
ATOM   2099 H H      . ILE A 1 140 ? 12.888  -29.002 31.936  1    15.354 ? 1148 ILE A H      1 ? 
ATOM   2100 H HA     . ILE A 1 140 ? 10.429  -28.825 30.196  0.57 18.299 ? 1148 ILE A HA     1 c 
ATOM   2101 H HB     . ILE A 1 140 ? 13.296  -28.001 29.506  0.63 20.039 ? 1148 ILE A HB     1 c 
ATOM   2102 H HG12   . ILE A 1 140 ? 12.32   -26.351 30.971  0.6  21.804 ? 1148 ILE A HG12   1 c 
ATOM   2103 H HG13   . ILE A 1 140 ? 12.429  -25.712 29.323  0.45 21.871 ? 1148 ILE A HG13   1 c 
ATOM   2104 H HG21   . ILE A 1 140 ? 12.207  -28.847 27.533  1    19.556 ? 1148 ILE A HG21   1 c 
ATOM   2105 H HG22   . ILE A 1 140 ? 10.721  -27.931 27.886  1    19.599 ? 1148 ILE A HG22   1 c 
ATOM   2106 H HG23   . ILE A 1 140 ? 12.211  -27.07  27.421  1    19.538 ? 1148 ILE A HG23   1 c 
ATOM   2107 H HD11   . ILE A 1 140 ? 10.06   -26.255 28.953  1    23.088 ? 1148 ILE A HD11   1 c 
ATOM   2108 H HD12   . ILE A 1 140 ? 9.945   -26.881 30.616  0.71 23.026 ? 1148 ILE A HD12   1 c 
ATOM   2109 H HD13   . ILE A 1 140 ? 10.294  -25.159 30.336  0.46 23.095 ? 1148 ILE A HD13   1 c 
ATOM   2110 N N      . GLN A 1 141 ? 11.127  -30.995 29.083  1    17.993 ? 1149 GLN A N      1 ? 
ATOM   2111 C CA     . GLN A 1 141 ? 11.52   -32.236 28.416  1    17.336 ? 1149 GLN A CA     1 ? 
ATOM   2112 C C      . GLN A 1 141 ? 12.06   -31.883 27.031  1    16.704 ? 1149 GLN A C      1 ? 
ATOM   2113 O O      . GLN A 1 141 ? 11.303  -31.482 26.136  1    16.814 ? 1149 GLN A O      1 ? 
ATOM   2114 C CB     . GLN A 1 141 ? 10.328  -33.188 28.325  1    20.448 ? 1149 GLN A CB     1 ? 
ATOM   2115 C CG     . GLN A 1 141 ? 9.811   -33.713 29.657  1    22.672 ? 1149 GLN A CG     1 ? 
ATOM   2116 C CD     . GLN A 1 141 ? 10.843  -34.55  30.388  1    29.783 ? 1149 GLN A CD     1 ? 
ATOM   2117 O OE1    . GLN A 1 141 ? 11.624  -33.985 31.15   1    31.891 ? 1149 GLN A OE1    1 ? 
ATOM   2118 N NE2    . GLN A 1 141 ? 10.795  -35.864 30.208  1    32.471 ? 1149 GLN A NE2    1 ? 
ATOM   2119 H H      . GLN A 1 141 ? 10.144  -30.682 29      1    18.306 ? 1149 GLN A H      1 ? 
ATOM   2120 H HA     . GLN A 1 141 ? 12.315  -32.707 28.997  1    17.953 ? 1149 GLN A HA     1 c 
ATOM   2121 H HB2    . GLN A 1 141 ? 9.513   -32.669 27.815  1    20.172 ? 1149 GLN A HB2    1 c 
ATOM   2122 H HB3    . GLN A 1 141 ? 10.614  -34.038 27.702  1    20.172 ? 1149 GLN A HB3    1 c 
ATOM   2123 H HG2    . GLN A 1 141 ? 9.523   -32.872 30.291  1    23.557 ? 1149 GLN A HG2    1 c 
ATOM   2124 H HG3    . GLN A 1 141 ? 8.921   -34.322 29.484  1    23.616 ? 1149 GLN A HG3    1 c 
ATOM   2125 H HE21   . GLN A 1 141 ? 10.121  -36.256 29.557  1    31.271 ? 1149 GLN A HE21   1 ? 
ATOM   2126 H HE22   . GLN A 1 141 ? 11.435  -36.468 30.711  1    30.249 ? 1149 GLN A HE22   1 ? 
ATOM   2127 N N      . LEU A 1 142 ? 13.372  -32.025 26.873  1    16.737 ? 1150 LEU A N      1 ? 
ATOM   2128 C CA     . LEU A 1 142 ? 14.108  -31.654 25.669  1    17.688 ? 1150 LEU A CA     1 ? 
ATOM   2129 C C      . LEU A 1 142 ? 14.469  -32.876 24.84   1    16.966 ? 1150 LEU A C      1 ? 
ATOM   2130 O O      . LEU A 1 142 ? 14.943  -33.88  25.376  1    17.169 ? 1150 LEU A O      1 ? 
ATOM   2131 C CB     . LEU A 1 142 ? 15.4    -30.957 26.097  1    20.005 ? 1150 LEU A CB     1 ? 
ATOM   2132 C CG     . LEU A 1 142 ? 15.987  -29.833 25.256  1    22.716 ? 1150 LEU A CG     1 ? 
ATOM   2133 C CD1    . LEU A 1 142 ? 15.021  -28.681 25.059  1    23.178 ? 1150 LEU A CD1    1 ? 
ATOM   2134 C CD2    . LEU A 1 142 ? 17.276  -29.367 25.934  1    23.694 ? 1150 LEU A CD2    1 ? 
ATOM   2135 H H      . LEU A 1 142 ? 13.914  -32.443 27.658  1    16.831 ? 1150 LEU A H      1 ? 
ATOM   2136 H HA     . LEU A 1 142 ? 13.5    -30.973 25.075  1    17.821 ? 1150 LEU A HA     1 c 
ATOM   2137 H HB2    . LEU A 1 142 ? 15.244  -30.569 27.106  1    19.996 ? 1150 LEU A HB2    1 c 
ATOM   2138 H HB3    . LEU A 1 142 ? 16.168  -31.727 26.204  1    19.999 ? 1150 LEU A HB3    1 c 
ATOM   2139 H HG     . LEU A 1 142 ? 16.243  -30.237 24.274  1    22.451 ? 1150 LEU A HG     1 c 
ATOM   2140 H HD11   . LEU A 1 142 ? 14.133  -29.034 24.53   1    22.957 ? 1150 LEU A HD11   1 c 
ATOM   2141 H HD12   . LEU A 1 142 ? 14.728  -28.28  26.032  1    23.016 ? 1150 LEU A HD12   1 c 
ATOM   2142 H HD13   . LEU A 1 142 ? 15.503  -27.896 24.474  1    22.972 ? 1150 LEU A HD13   1 c 
ATOM   2143 H HD21   . LEU A 1 142 ? 17.978  -30.201 25.994  1    23.393 ? 1150 LEU A HD21   1 c 
ATOM   2144 H HD22   . LEU A 1 142 ? 17.722  -28.558 25.352  1    23.393 ? 1150 LEU A HD22   1 c 
ATOM   2145 H HD23   . LEU A 1 142 ? 17.05   -29.009 26.94   1    23.312 ? 1150 LEU A HD23   1 c 
ATOM   2146 N N      . THR A 1 143 ? 14.306  -32.759 23.516  1    15.562 ? 1151 THR A N      1 ? 
ATOM   2147 C CA     . THR A 1 143 ? 14.736  -33.8   22.589  1    17.582 ? 1151 THR A CA     1 ? 
ATOM   2148 C C      . THR A 1 143 ? 15.608  -33.192 21.494  1    16.828 ? 1151 THR A C      1 ? 
ATOM   2149 O O      . THR A 1 143 ? 15.653  -31.97  21.291  1    16.81  ? 1151 THR A O      1 ? 
ATOM   2150 C CB     . THR A 1 143 ? 13.54   -34.551 21.972  1    19.345 ? 1151 THR A CB     1 ? 
ATOM   2151 O OG1    . THR A 1 143 ? 12.796  -33.667 21.127  1    19.948 ? 1151 THR A OG1    1 ? 
ATOM   2152 C CG2    . THR A 1 143 ? 12.612  -35.113 23.045  1    21.494 ? 1151 THR A CG2    1 ? 
ATOM   2153 H H      . THR A 1 143 ? 13.835  -31.918 23.13   1    17.372 ? 1151 THR A H      1 ? 
ATOM   2154 H HA     . THR A 1 143 ? 15.339  -34.521 23.144  1    17.335 ? 1151 THR A HA     1 c 
ATOM   2155 H HB     . THR A 1 143 ? 13.915  -35.383 21.372  1    19.498 ? 1151 THR A HB     1 c 
ATOM   2156 H HG1    . THR A 1 143 ? 13.064  -33.771 20.22   1    19.654 ? 1151 THR A HG1    1 ? 
ATOM   2157 H HG21   . THR A 1 143 ? 11.774  -35.626 22.57   1    20.865 ? 1151 THR A HG21   1 c 
ATOM   2158 H HG22   . THR A 1 143 ? 13.163  -35.819 23.671  1    20.848 ? 1151 THR A HG22   1 c 
ATOM   2159 H HG23   . THR A 1 143 ? 12.234  -34.297 23.665  1    20.747 ? 1151 THR A HG23   1 c 
ATOM   2160 N N      . GLY A 1 144 ? 16.293  -34.071 20.772  1    17.109 ? 1152 GLY A N      1 ? 
ATOM   2161 C CA     . GLY A 1 144 ? 17.112  -33.674 19.653  1    18.045 ? 1152 GLY A CA     1 ? 
ATOM   2162 C C      . GLY A 1 144 ? 18.584  -33.64  20.03   1    16.808 ? 1152 GLY A C      1 ? 
ATOM   2163 O O      . GLY A 1 144 ? 19.062  -34.462 20.816  1    16.333 ? 1152 GLY A O      1 ? 
ATOM   2164 H H      . GLY A 1 144 ? 16.274  -35.064 21.042  1    18.914 ? 1152 GLY A H      1 ? 
ATOM   2165 H HA2    . GLY A 1 144 ? 16.965  -34.387 18.838  1    17.547 ? 1152 GLY A HA2    1 c 
ATOM   2166 H HA3    . GLY A 1 144 ? 16.793  -32.695 19.299  1    17.513 ? 1152 GLY A HA3    1 c 
ATOM   2167 N N      . PRO A 1 145 ? 19.345  -32.69  19.457  1    15.945 ? 1153 PRO A N      1 ? 
ATOM   2168 C CA     . PRO A 1 145 ? 18.87   -31.701 18.491  1    16.563 ? 1153 PRO A CA     1 ? 
ATOM   2169 C C      . PRO A 1 145 ? 18.561  -32.369 17.16   1    17.815 ? 1153 PRO A C      1 ? 
ATOM   2170 O O      . PRO A 1 145 ? 18.809  -33.566 16.964  1    13.85  ? 1153 PRO A O      1 ? 
ATOM   2171 C CB     . PRO A 1 145 ? 20.048  -30.734 18.363  1    15.327 ? 1153 PRO A CB     1 ? 
ATOM   2172 C CG     . PRO A 1 145 ? 21.231  -31.565 18.651  1    15.585 ? 1153 PRO A CG     1 ? 
ATOM   2173 C CD     . PRO A 1 145 ? 20.802  -32.641 19.625  1    15.069 ? 1153 PRO A CD     1 ? 
ATOM   2174 H HA     . PRO A 1 145 ? 17.987  -31.187 18.876  1    16.437 ? 1153 PRO A HA     1 c 
ATOM   2175 H HB2    . PRO A 1 145 ? 20.101  -30.317 17.355  1    15.64  ? 1153 PRO A HB2    1 c 
ATOM   2176 H HB3    . PRO A 1 145 ? 19.961  -29.917 19.081  1    15.64  ? 1153 PRO A HB3    1 c 
ATOM   2177 H HG2    . PRO A 1 145 ? 21.61   -32.018 17.734  1    15.431 ? 1153 PRO A HG2    1 c 
ATOM   2178 H HG3    . PRO A 1 145 ? 22.024  -30.957 19.088  1    15.413 ? 1153 PRO A HG3    1 c 
ATOM   2179 H HD2    . PRO A 1 145 ? 21.253  -33.604 19.376  1    15.371 ? 1153 PRO A HD2    1 c 
ATOM   2180 H HD3    . PRO A 1 145 ? 21.064  -32.375 20.651  1    15.371 ? 1153 PRO A HD3    1 c 
ATOM   2181 N N      . SER A 1 146 ? 17.987  -31.606 16.244  1    17.013 ? 1154 SER A N      1 ? 
ATOM   2182 C CA     . SER A 1 146 ? 17.761  -32.169 14.928  1    18.686 ? 1154 SER A CA     1 ? 
ATOM   2183 C C      . SER A 1 146 ? 17.832  -31.083 13.875  1    19.521 ? 1154 SER A C      1 ? 
ATOM   2184 O O      . SER A 1 146 ? 17.814  -29.881 14.168  1    18.04  ? 1154 SER A O      1 ? 
ATOM   2185 C CB     . SER A 1 146 ? 16.43   -32.919 14.845  1    20.042 ? 1154 SER A CB     1 ? 
ATOM   2186 O OG     . SER A 1 146 ? 15.374  -32.002 15      1    20.856 ? 1154 SER A OG     1 ? 
ATOM   2187 H H      . SER A 1 146 ? 17.639  -30.667 16.471  1    16.879 ? 1154 SER A H      1 ? 
ATOM   2188 H HA     . SER A 1 146 ? 18.563  -32.88  14.724  1    18.688 ? 1154 SER A HA     1 c 
ATOM   2189 H HB2    . SER A 1 146 ? 16.348  -33.417 13.877  1    19.932 ? 1154 SER A HB2    1 c 
ATOM   2190 H HB3    . SER A 1 146 ? 16.384  -33.673 15.634  1    19.932 ? 1154 SER A HB3    1 c 
ATOM   2191 H HG     . SER A 1 146 ? 15.156  -31.985 15.95   1    20.205 ? 1154 SER A HG     1 ? 
ATOM   2192 N N      . GLY A 1 147 ? 17.919  -31.544 12.636  1    20.307 ? 1155 GLY A N      1 ? 
ATOM   2193 C CA     . GLY A 1 147 ? 17.98   -30.655 11.5    1    18.802 ? 1155 GLY A CA     1 ? 
ATOM   2194 C C      . GLY A 1 147 ? 19.395  -30.447 11.006  1    19.388 ? 1155 GLY A C      1 ? 
ATOM   2195 O O      . GLY A 1 147 ? 20.332  -30.313 11.776  1    22.124 ? 1155 GLY A O      1 ? 
ATOM   2196 H H      . GLY A 1 147 ? 17.958  -32.577 12.482  1    17.711 ? 1155 GLY A H      1 ? 
ATOM   2197 H HA2    . GLY A 1 147 ? 17.37   -31.067 10.693  1    19.264 ? 1155 GLY A HA2    1 c 
ATOM   2198 H HA3    . GLY A 1 147 ? 17.554  -29.692 11.786  1    19.321 ? 1155 GLY A HA3    1 c 
ATOM   2199 N N      . LYS A 1 148 ? 19.51   -30.424 9.675   1    17.758 ? 1156 LYS A N      1 ? 
ATOM   2200 C CA     . LYS A 1 148 ? 20.742  -30.036 9.008   1    19.823 ? 1156 LYS A CA     1 ? 
ATOM   2201 C C      . LYS A 1 148 ? 20.56   -28.957 7.943   1    18.731 ? 1156 LYS A C      1 ? 
ATOM   2202 O O      . LYS A 1 148 ? 21.567  -28.464 7.435   1    17.274 ? 1156 LYS A O      1 ? 
ATOM   2203 C CB     . LYS A 1 148 ? 21.422  -31.246 8.36    1    21.998 ? 1156 LYS A CB     1 ? 
ATOM   2204 C CG     . LYS A 1 148 ? 21.759  -32.363 9.319   1    28.181 ? 1156 LYS A CG     1 ? 
ATOM   2205 C CD     . LYS A 1 148 ? 22.777  -33.311 8.702   1    33.157 ? 1156 LYS A CD     1 ? 
ATOM   2206 C CE     . LYS A 1 148 ? 22.151  -34.284 7.75    1    40.828 ? 1156 LYS A CE     1 ? 
ATOM   2207 N NZ     . LYS A 1 148 ? 23.161  -35.318 7.49    1    45.837 ? 1156 LYS A NZ     1 ? 
ATOM   2208 H H      . LYS A 1 148 ? 18.728  -30.765 9.095   1    17.97  ? 1156 LYS A H      1 ? 
ATOM   2209 H HA     . LYS A 1 148 ? 21.423  -29.645 9.765   1    19.561 ? 1156 LYS A HA     1 c 
ATOM   2210 H HB2    . LYS A 1 148 ? 20.765  -31.643 7.584   1    22.717 ? 1156 LYS A HB2    1 c 
ATOM   2211 H HB3    . LYS A 1 148 ? 22.344  -30.914 7.878   1    22.688 ? 1156 LYS A HB3    1 c 
ATOM   2212 H HG2    . LYS A 1 148 ? 22.167  -31.935 10.238  1    27.636 ? 1156 LYS A HG2    1 c 
ATOM   2213 H HG3    . LYS A 1 148 ? 20.848  -32.912 9.564   1    27.636 ? 1156 LYS A HG3    1 c 
ATOM   2214 H HD2    . LYS A 1 148 ? 23.531  -32.727 8.17    1    33.518 ? 1156 LYS A HD2    1 c 
ATOM   2215 H HD3    . LYS A 1 148 ? 23.278  -33.864 9.499   1    33.518 ? 1156 LYS A HD3    1 c 
ATOM   2216 H HE2    . LYS A 1 148 ? 21.263  -34.739 8.192   1    40.006 ? 1156 LYS A HE2    1 c 
ATOM   2217 H HE3    . LYS A 1 148 ? 21.877  -33.79  6.816   1    40.039 ? 1156 LYS A HE3    1 c 
ATOM   2218 H HZ1    . LYS A 1 148 ? 23.313  -35.869 8.346   1    43.102 ? 1156 LYS A HZ1    1 ? 
ATOM   2219 H HZ2    . LYS A 1 148 ? 22.87   -35.937 6.738   1    44.064 ? 1156 LYS A HZ2    1 ? 
ATOM   2220 H HZ3    . LYS A 1 148 ? 24.041  -34.851 7.227   1    42.473 ? 1156 LYS A HZ3    1 ? 
ATOM   2221 N N      . ILE A 1 149 ? 19.329  -28.57  7.606   1    18.197 ? 1157 ILE A N      1 ? 
ATOM   2222 C CA     . ILE A 1 149 ? 19.144  -27.669 6.485   1    17.578 ? 1157 ILE A CA     1 ? 
ATOM   2223 C C      . ILE A 1 149 ? 19.83   -26.321 6.734   1    15.891 ? 1157 ILE A C      1 ? 
ATOM   2224 O O      . ILE A 1 149 ? 20.346  -25.701 5.799   1    15.155 ? 1157 ILE A O      1 ? 
ATOM   2225 C CB     . ILE A 1 149 ? 17.656  -27.483 6.159   1    19.337 ? 1157 ILE A CB     1 ? 
ATOM   2226 C CG1    . ILE A 1 149 ? 17.055  -28.731 5.532   1    20.068 ? 1157 ILE A CG1    1 ? 
ATOM   2227 C CG2    . ILE A 1 149 ? 17.482  -26.288 5.218   1    19.023 ? 1157 ILE A CG2    1 ? 
ATOM   2228 C CD1    . ILE A 1 149 ? 15.552  -28.543 5.317   1    22.997 ? 1157 ILE A CD1    1 ? 
ATOM   2229 H H      . ILE A 1 149 ? 18.542  -28.829 8.232   1    15.205 ? 1157 ILE A H      1 ? 
ATOM   2230 H HA     . ILE A 1 149 ? 19.617  -28.127 5.614   1    17.676 ? 1157 ILE A HA     1 c 
ATOM   2231 H HB     . ILE A 1 149 ? 17.123  -27.273 7.088   1    19.082 ? 1157 ILE A HB     1 c 
ATOM   2232 H HG12   . ILE A 1 149 ? 17.539  -28.928 4.573   1    20.519 ? 1157 ILE A HG12   1 c 
ATOM   2233 H HG13   . ILE A 1 149 ? 17.225  -29.587 6.189   1    20.588 ? 1157 ILE A HG13   1 c 
ATOM   2234 H HG21   . ILE A 1 149 ? 18.112  -26.422 4.336   1    19.095 ? 1157 ILE A HG21   1 c 
ATOM   2235 H HG22   . ILE A 1 149 ? 16.44   -26.212 4.908   1    19.121 ? 1157 ILE A HG22   1 c 
ATOM   2236 H HG23   . ILE A 1 149 ? 17.771  -25.369 5.732   1    19.027 ? 1157 ILE A HG23   1 c 
ATOM   2237 H HD11   . ILE A 1 149 ? 15.104  -29.499 5.037   1    22.155 ? 1157 ILE A HD11   1 c 
ATOM   2238 H HD12   . ILE A 1 149 ? 15.095  -28.186 6.242   1    22.156 ? 1157 ILE A HD12   1 c 
ATOM   2239 H HD13   . ILE A 1 149 ? 15.375  -27.816 4.522   1    22.192 ? 1157 ILE A HD13   1 c 
ATOM   2240 N N      . MET A 1 150 ? 19.849  -25.864 7.982   1    15.379 ? 1158 MET A N      1 ? 
ATOM   2241 C CA     . MET A 1 150 ? 20.308  -24.525 8.308   1    15.796 ? 1158 MET A CA     1 ? 
ATOM   2242 C C      . MET A 1 150 ? 21.691  -24.542 8.97    1    14.753 ? 1158 MET A C      1 ? 
ATOM   2243 O O      . MET A 1 150 ? 22.094  -23.554 9.591   1    15.032 ? 1158 MET A O      1 ? 
ATOM   2244 C CB     . MET A 1 150 ? 19.282  -23.885 9.236   1    16.406 ? 1158 MET A CB     1 ? 
ATOM   2245 C CG     . MET A 1 150 ? 17.937  -23.575 8.587   1    17.729 ? 1158 MET A CG     1 ? 
ATOM   2246 S SD     . MET A 1 150 ? 17.889  -22.632 7.054   1    17.625 ? 1158 MET A SD     1 ? 
ATOM   2247 C CE     . MET A 1 150 ? 18.047  -20.99  7.777   1    18.574 ? 1158 MET A CE     1 ? 
ATOM   2248 H H      . MET A 1 150 ? 19.476  -26.442 8.751   1    15.264 ? 1158 MET A H      1 ? 
ATOM   2249 H HA     . MET A 1 150 ? 20.373  -23.947 7.385   1    15.638 ? 1158 MET A HA     1 c 
ATOM   2250 H HB2    . MET A 1 150 ? 19.116  -24.556 10.08   1    16.563 ? 1158 MET A HB2    1 c 
ATOM   2251 H HB3    . MET A 1 150 ? 19.702  -22.957 9.63    1    16.542 ? 1158 MET A HB3    1 c 
ATOM   2252 H HG2    . MET A 1 150 ? 17.43   -24.524 8.4     1    17.397 ? 1158 MET A HG2    1 c 
ATOM   2253 H HG3    . MET A 1 150 ? 17.33   -23.036 9.318   1    17.397 ? 1158 MET A HG3    1 c 
ATOM   2254 H HE1    . MET A 1 150 ? 17.903  -20.236 7.001   1    18.302 ? 1158 MET A HE1    1 c 
ATOM   2255 H HE2    . MET A 1 150 ? 17.289  -20.861 8.552   1    18.331 ? 1158 MET A HE2    1 c 
ATOM   2256 H HE3    . MET A 1 150 ? 19.04   -20.881 8.22    1    18.319 ? 1158 MET A HE3    1 c 
ATOM   2257 N N      . LEU A 1 151 ? 22.451  -25.628 8.832   1    15.724 ? 1159 LEU A N      1 ? 
ATOM   2258 C CA     . LEU A 1 151 ? 23.839  -25.579 9.276   1    14.379 ? 1159 LEU A CA     1 ? 
ATOM   2259 C C      . LEU A 1 151 ? 24.579  -24.486 8.496   1    15.427 ? 1159 LEU A C      1 ? 
ATOM   2260 O O      . LEU A 1 151 ? 24.323  -24.249 7.318   1    17.642 ? 1159 LEU A O      1 ? 
ATOM   2261 C CB     . LEU A 1 151 ? 24.527  -26.926 9.084   1    15.172 ? 1159 LEU A CB     1 ? 
ATOM   2262 C CG     . LEU A 1 151 ? 23.951  -28.1   9.867   1    17.067 ? 1159 LEU A CG     1 ? 
ATOM   2263 C CD1    . LEU A 1 151 ? 24.696  -29.389 9.514   1    16.432 ? 1159 LEU A CD1    1 ? 
ATOM   2264 C CD2    . LEU A 1 151 ? 23.981  -27.827 11.361  1    14.518 ? 1159 LEU A CD2    1 ? 
ATOM   2265 H H      . LEU A 1 151 ? 22.068  -26.44  8.322   1    14.467 ? 1159 LEU A H      1 ? 
ATOM   2266 H HA     . LEU A 1 151 ? 23.851  -25.318 10.336  1    14.948 ? 1159 LEU A HA     1 c 
ATOM   2267 H HB2    . LEU A 1 151 ? 24.495  -27.175 8.021   1    15.386 ? 1159 LEU A HB2    1 c 
ATOM   2268 H HB3    . LEU A 1 151 ? 25.577  -26.812 9.36    1    15.386 ? 1159 LEU A HB3    1 c 
ATOM   2269 H HG     . LEU A 1 151 ? 22.908  -28.223 9.571   1    16.15  ? 1159 LEU A HG     1 c 
ATOM   2270 H HD11   . LEU A 1 151 ? 25.73   -29.321 9.858   1    16.604 ? 1159 LEU A HD11   1 c 
ATOM   2271 H HD12   . LEU A 1 151 ? 24.206  -30.235 9.999   1    16.635 ? 1159 LEU A HD12   1 c 
ATOM   2272 H HD13   . LEU A 1 151 ? 24.681  -29.535 8.432   1    16.571 ? 1159 LEU A HD13   1 c 
ATOM   2273 H HD21   . LEU A 1 151 ? 25.006  -27.616 11.673  1    15.185 ? 1159 LEU A HD21   1 c 
ATOM   2274 H HD22   . LEU A 1 151 ? 23.348  -26.967 11.589  1    15.18  ? 1159 LEU A HD22   1 c 
ATOM   2275 H HD23   . LEU A 1 151 ? 23.611  -28.702 11.899  1    15.185 ? 1159 LEU A HD23   1 c 
ATOM   2276 N N      . LEU A 1 152 ? 25.507  -23.816 9.171   1    15.321 ? 1160 LEU A N      1 ? 
ATOM   2277 C CA     . LEU A 1 152 ? 26.253  -22.736 8.542   1    15.456 ? 1160 LEU A CA     1 ? 
ATOM   2278 C C      . LEU A 1 152 ? 27.407  -23.314 7.721   1    15.589 ? 1160 LEU A C      1 ? 
ATOM   2279 O O      . LEU A 1 152 ? 28.254  -24.022 8.275   1    13.759 ? 1160 LEU A O      1 ? 
ATOM   2280 C CB     . LEU A 1 152 ? 26.815  -21.815 9.614   1    15.958 ? 1160 LEU A CB     1 ? 
ATOM   2281 C CG     . LEU A 1 152 ? 27.583  -20.591 9.088   1    16.34  ? 1160 LEU A CG     1 ? 
ATOM   2282 C CD1    . LEU A 1 152 ? 26.661  -19.653 8.3     1    16.546 ? 1160 LEU A CD1    1 ? 
ATOM   2283 C CD2    . LEU A 1 152 ? 28.22   -19.852 10.249  1    17.498 ? 1160 LEU A CD2    1 ? 
ATOM   2284 H H      . LEU A 1 152 ? 25.646  -24.021 10.167  1    15.223 ? 1160 LEU A H      1 ? 
ATOM   2285 H HA     . LEU A 1 152 ? 25.582  -22.173 7.893   1    15.583 ? 1160 LEU A HA     1 c 
ATOM   2286 H HB2    . LEU A 1 152 ? 25.987  -21.464 10.232  1    15.927 ? 1160 LEU A HB2    1 c 
ATOM   2287 H HB3    . LEU A 1 152 ? 27.486  -22.398 10.248  1    15.927 ? 1160 LEU A HB3    1 c 
ATOM   2288 H HG     . LEU A 1 152 ? 28.377  -20.937 8.423   1    16.507 ? 1160 LEU A HG     1 c 
ATOM   2289 H HD11   . LEU A 1 152 ? 26.253  -20.183 7.436   1    16.473 ? 1160 LEU A HD11   1 c 
ATOM   2290 H HD12   . LEU A 1 152 ? 25.843  -19.321 8.941   1    16.483 ? 1160 LEU A HD12   1 c 
ATOM   2291 H HD13   . LEU A 1 152 ? 27.229  -18.786 7.957   1    16.476 ? 1160 LEU A HD13   1 c 
ATOM   2292 H HD21   . LEU A 1 152 ? 28.764  -18.982 9.874   1    17.158 ? 1160 LEU A HD21   1 c 
ATOM   2293 H HD22   . LEU A 1 152 ? 27.443  -19.522 10.942  1    17.158 ? 1160 LEU A HD22   1 c 
ATOM   2294 H HD23   . LEU A 1 152 ? 28.912  -20.516 10.77   1    17.131 ? 1160 LEU A HD23   1 c 
ATOM   2295 N N      . PRO A 1 153 ? 27.477  -23.053 6.401   1    15.766 ? 1161 PRO A N      1 ? 
ATOM   2296 C CA     . PRO A 1 153 ? 28.634  -23.497 5.632   1    16.158 ? 1161 PRO A CA     1 ? 
ATOM   2297 C C      . PRO A 1 153 ? 29.874  -22.701 6.017   1    15.927 ? 1161 PRO A C      1 ? 
ATOM   2298 O O      . PRO A 1 153 ? 29.945  -21.5   5.757   1    17.317 ? 1161 PRO A O      1 ? 
ATOM   2299 C CB     . PRO A 1 153 ? 28.225  -23.259 4.175   1    16.494 ? 1161 PRO A CB     1 ? 
ATOM   2300 C CG     . PRO A 1 153 ? 26.719  -23.102 4.22    1    17.137 ? 1161 PRO A CG     1 ? 
ATOM   2301 C CD     . PRO A 1 153 ? 26.45   -22.455 5.534   1    17.024 ? 1161 PRO A CD     1 ? 
ATOM   2302 H HA     . PRO A 1 153 ? 28.807  -24.561 5.806   1    16.087 ? 1161 PRO A HA     1 c 
ATOM   2303 H HB2    . PRO A 1 153 ? 28.698  -22.358 3.779   1    16.586 ? 1161 PRO A HB2    1 c 
ATOM   2304 H HB3    . PRO A 1 153 ? 28.508  -24.108 3.55    1    16.564 ? 1161 PRO A HB3    1 c 
ATOM   2305 H HG2    . PRO A 1 153 ? 26.368  -22.471 3.4     1    16.972 ? 1161 PRO A HG2    1 c 
ATOM   2306 H HG3    . PRO A 1 153 ? 26.222  -24.072 4.158   1    16.972 ? 1161 PRO A HG3    1 c 
ATOM   2307 H HD2    . PRO A 1 153 ? 26.576  -21.373 5.479   1    16.757 ? 1161 PRO A HD2    1 c 
ATOM   2308 H HD3    . PRO A 1 153 ? 25.447  -22.686 5.895   1    16.749 ? 1161 PRO A HD3    1 c 
ATOM   2309 N N      . GLU A 1 154 ? 30.837  -23.358 6.664   1    15.89  ? 1162 GLU A N      1 ? 
ATOM   2310 C CA     . GLU A 1 154 ? 32.029  -22.699 7.181   1    18.123 ? 1162 GLU A CA     1 ? 
ATOM   2311 C C      . GLU A 1 154 ? 33.28   -22.965 6.36    1    18.458 ? 1162 GLU A C      1 ? 
ATOM   2312 O O      . GLU A 1 154 ? 34.342  -22.417 6.683   1    21.804 ? 1162 GLU A O      1 ? 
ATOM   2313 C CB     . GLU A 1 154 ? 32.278  -23.06  8.653   1    18.293 ? 1162 GLU A CB     1 ? 
ATOM   2314 C CG     . GLU A 1 154 ? 31.136  -22.61  9.545   1    19.455 ? 1162 GLU A CG     1 ? 
ATOM   2315 C CD     . GLU A 1 154 ? 31.343  -22.9   11.009  1    19.417 ? 1162 GLU A CD     1 ? 
ATOM   2316 O OE1    . GLU A 1 154 ? 32.443  -23.345 11.43   1    22.053 ? 1162 GLU A OE1    1 ? 
ATOM   2317 O OE2    . GLU A 1 154 ? 30.387  -22.633 11.757  1    20.693 ? 1162 GLU A OE2    1 ? 
ATOM   2318 H H      . GLU A 1 154 ? 30.704  -24.357 6.883   1    15.259 ? 1162 GLU A H      1 ? 
ATOM   2319 H HA     . GLU A 1 154 ? 31.846  -21.624 7.155   1    17.767 ? 1162 GLU A HA     1 c 
ATOM   2320 H HB2    . GLU A 1 154 ? 32.404  -24.141 8.738   1    18.515 ? 1162 GLU A HB2    1 c 
ATOM   2321 H HB3    . GLU A 1 154 ? 33.205  -22.587 8.984   1    18.563 ? 1162 GLU A HB3    1 c 
ATOM   2322 H HG2    . GLU A 1 154 ? 30.992  -21.535 9.422   1    19.178 ? 1162 GLU A HG2    1 c 
ATOM   2323 H HG3    . GLU A 1 154 ? 30.219  -23.103 9.223   1    19.143 ? 1162 GLU A HG3    1 c 
ATOM   2324 N N      . GLU A 1 155 ? 33.181  -23.753 5.285   1    19.095 ? 1163 GLU A N      1 ? 
ATOM   2325 C CA     . GLU A 1 155 ? 34.359  -24.102 4.483   1    21.215 ? 1163 GLU A CA     1 ? 
ATOM   2326 C C      . GLU A 1 155 ? 35.072  -22.844 3.973   1    21.107 ? 1163 GLU A C      1 ? 
ATOM   2327 O O      . GLU A 1 155 ? 36.301  -22.813 3.876   1    20.333 ? 1163 GLU A O      1 ? 
ATOM   2328 C CB     . GLU A 1 155 ? 34.043  -24.946 3.246   1    25.562 ? 1163 GLU A CB     1 ? 
ATOM   2329 C CG     . GLU A 1 155 ? 33.337  -26.272 3.537   1    32.701 ? 1163 GLU A CG     1 ? 
ATOM   2330 C CD     . GLU A 1 155 ? 31.955  -26.202 4.206   1    35.82  ? 1163 GLU A CD     1 ? 
ATOM   2331 O OE1    . GLU A 1 155 ? 31.128  -25.301 3.886   1    31.339 ? 1163 GLU A OE1    1 ? 
ATOM   2332 O OE2    . GLU A 1 155 ? 31.696  -27.101 5.042   1    35.139 ? 1163 GLU A OE2    1 ? 
ATOM   2333 H H      . GLU A 1 155 ? 32.285  -24.204 5.055   1    20.596 ? 1163 GLU A H      1 ? 
ATOM   2334 H HA     . GLU A 1 155 ? 35.051  -24.66  5.119   1    21.48  ? 1163 GLU A HA     1 c 
ATOM   2335 H HB2    . GLU A 1 155 ? 33.414  -24.358 2.574   1    25.903 ? 1163 GLU A HB2    1 c 
ATOM   2336 H HB3    . GLU A 1 155 ? 34.977  -25.159 2.721   1    25.903 ? 1163 GLU A HB3    1 c 
ATOM   2337 H HG2    . GLU A 1 155 ? 33.227  -26.816 2.597   1    31.601 ? 1163 GLU A HG2    1 c 
ATOM   2338 H HG3    . GLU A 1 155 ? 33.987  -26.875 4.173   1    31.601 ? 1163 GLU A HG3    1 c 
ATOM   2339 N N      . ASP A 1 156 ? 34.302  -21.824 3.589   1    20.252 ? 1164 ASP A N      1 ? 
ATOM   2340 C CA     . ASP A 1 156 ? 34.853  -20.553 3.14    1    18.234 ? 1164 ASP A CA     1 ? 
ATOM   2341 C C      . ASP A 1 156 ? 34.591  -19.521 4.23    1    19.258 ? 1164 ASP A C      1 ? 
ATOM   2342 O O      . ASP A 1 156 ? 33.463  -19.024 4.355   1    15.235 ? 1164 ASP A O      1 ? 
ATOM   2343 C CB     . ASP A 1 156 ? 34.199  -20.131 1.828   1    19.681 ? 1164 ASP A CB     1 ? 
ATOM   2344 C CG     . ASP A 1 156 ? 34.68   -18.785 1.327   1    19.338 ? 1164 ASP A CG     1 ? 
ATOM   2345 O OD1    . ASP A 1 156 ? 35.617  -18.234 1.93    1    20.04  ? 1164 ASP A OD1    1 ? 
ATOM   2346 O OD2    . ASP A 1 156 ? 34.129  -18.292 0.322   1    21.542 ? 1164 ASP A OD2    1 ? 
ATOM   2347 H H      . ASP A 1 156 ? 33.27   -21.919 3.658   1    18.452 ? 1164 ASP A H      1 ? 
ATOM   2348 H HA     . ASP A 1 156 ? 35.927  -20.664 2.988   1    19.199 ? 1164 ASP A HA     1 c 
ATOM   2349 H HB2    . ASP A 1 156 ? 34.415  -20.882 1.064   1    19.277 ? 1164 ASP A HB2    1 c 
ATOM   2350 H HB3    . ASP A 1 156 ? 33.117  -20.087 1.965   1    19.253 ? 1164 ASP A HB3    1 c 
ATOM   2351 N N      . PRO A 1 157 ? 35.592  -19.162 5.049   1    20.386 ? 1165 PRO A N      1 ? 
ATOM   2352 C CA     . PRO A 1 157 ? 35.355  -18.171 6.101   1    18.989 ? 1165 PRO A CA     1 ? 
ATOM   2353 C C      . PRO A 1 157 ? 35.132  -16.759 5.573   1    18.799 ? 1165 PRO A C      1 ? 
ATOM   2354 O O      . PRO A 1 157 ? 34.822  -15.861 6.365   1    18.649 ? 1165 PRO A O      1 ? 
ATOM   2355 C CB     . PRO A 1 157 ? 36.61   -18.265 6.973   1    21.405 ? 1165 PRO A CB     1 ? 
ATOM   2356 C CG     . PRO A 1 157 ? 37.667  -18.702 6.006   1    22.502 ? 1165 PRO A CG     1 ? 
ATOM   2357 C CD     . PRO A 1 157 ? 36.982  -19.646 5.05    1    21.202 ? 1165 PRO A CD     1 ? 
ATOM   2358 H HA     . PRO A 1 157 ? 34.486  -18.474 6.689   1    19.59  ? 1165 PRO A HA     1 c 
ATOM   2359 H HB2    . PRO A 1 157 ? 36.856  -17.296 7.41    1    21.063 ? 1165 PRO A HB2    1 c 
ATOM   2360 H HB3    . PRO A 1 157 ? 36.479  -18.999 7.771   1    21.088 ? 1165 PRO A HB3    1 c 
ATOM   2361 H HG2    . PRO A 1 157 ? 38.077  -17.844 5.468   1    21.972 ? 1165 PRO A HG2    1 c 
ATOM   2362 H HG3    . PRO A 1 157 ? 38.482  -19.21  6.527   1    21.972 ? 1165 PRO A HG3    1 c 
ATOM   2363 H HD2    . PRO A 1 157 ? 37.416  -19.584 4.05    1    21.269 ? 1165 PRO A HD2    1 c 
ATOM   2364 H HD3    . PRO A 1 157 ? 37.034  -20.678 5.403   1    21.284 ? 1165 PRO A HD3    1 c 
ATOM   2365 N N      . ASN A 1 158 ? 35.259  -16.552 4.261   1    19.994 ? 1166 ASN A N      1 ? 
ATOM   2366 C CA     . ASN A 1 158 ? 34.981  -15.273 3.625   1    20.054 ? 1166 ASN A CA     1 ? 
ATOM   2367 C C      . ASN A 1 158 ? 33.763  -15.345 2.704   1    18.786 ? 1166 ASN A C      1 ? 
ATOM   2368 O O      . ASN A 1 158 ? 33.593  -14.506 1.814   1    20.387 ? 1166 ASN A O      1 ? 
ATOM   2369 C CB     . ASN A 1 158 ? 36.221  -14.807 2.876   1    20.315 ? 1166 ASN A CB     1 ? 
ATOM   2370 C CG     . ASN A 1 158 ? 37.389  -14.595 3.814   1    22.92  ? 1166 ASN A CG     1 ? 
ATOM   2371 O OD1    . ASN A 1 158 ? 37.232  -14.075 4.921   1    20.474 ? 1166 ASN A OD1    1 ? 
ATOM   2372 N ND2    . ASN A 1 158 ? 38.56   -15.149 3.501   1    22.456 ? 1166 ASN A ND2    1 ? 
ATOM   2373 H H      . ASN A 1 158 ? 35.534  -17.335 3.632   1    19.288 ? 1166 ASN A H      1 ? 
ATOM   2374 H HA     . ASN A 1 158 ? 34.777  -14.539 4.406   1    19.825 ? 1166 ASN A HA     1 c 
ATOM   2375 H HB2    . ASN A 1 158 ? 36.492  -15.553 2.126   1    20.801 ? 1166 ASN A HB2    1 c 
ATOM   2376 H HB3    . ASN A 1 158 ? 36.001  -13.87  2.359   1    20.799 ? 1166 ASN A HB3    1 c 
ATOM   2377 H HD21   . ASN A 1 158 ? 39.397  -14.866 3.996   1    21.976 ? 1166 ASN A HD21   1 ? 
ATOM   2378 H HD22   . ASN A 1 158 ? 38.598  -15.869 2.789   1    21.219 ? 1166 ASN A HD22   1 ? 
ATOM   2379 N N      . ALA A 1 159 ? 32.901  -16.339 2.923   1    16.454 ? 1167 ALA A N      1 ? 
ATOM   2380 C CA     . ALA A 1 159 ? 31.664  -16.471 2.168   1    15.893 ? 1167 ALA A CA     1 ? 
ATOM   2381 C C      . ALA A 1 159 ? 30.729  -15.288 2.447   1    14.058 ? 1167 ALA A C      1 ? 
ATOM   2382 O O      . ALA A 1 159 ? 30.892  -14.529 3.407   1    14.368 ? 1167 ALA A O      1 ? 
ATOM   2383 C CB     . ALA A 1 159 ? 30.973  -17.781 2.548   1    16.218 ? 1167 ALA A CB     1 ? 
ATOM   2384 H H      . ALA A 1 159 ? 33.044  -17.016 3.684   1    16.149 ? 1167 ALA A H      1 ? 
ATOM   2385 H HA     . ALA A 1 159 ? 31.905  -16.481 1.104   1    15.709 ? 1167 ALA A HA     1 c 
ATOM   2386 H HB1    . ALA A 1 159 ? 30.753  -17.784 3.617   1    16.135 ? 1167 ALA A HB1    1 c 
ATOM   2387 H HB2    . ALA A 1 159 ? 30.041  -17.881 1.988   1    16.135 ? 1167 ALA A HB2    1 c 
ATOM   2388 H HB3    . ALA A 1 159 ? 31.627  -18.623 2.312   1    16.161 ? 1167 ALA A HB3    1 c 
ATOM   2389 N N      . THR A 1 160 ? 29.731  -15.142 1.579   1    13.612 ? 1168 THR A N      1 ? 
ATOM   2390 C CA     . THR A 1 160 ? 28.65   -14.191 1.778   1    14.52  ? 1168 THR A CA     1 ? 
ATOM   2391 C C      . THR A 1 160 ? 27.385  -14.957 2.166   1    15.078 ? 1168 THR A C      1 ? 
ATOM   2392 O O      . THR A 1 160 ? 27.06   -15.984 1.551   1    14.386 ? 1168 THR A O      1 ? 
ATOM   2393 C CB     . THR A 1 160 ? 28.431  -13.347 0.524   1    16.914 ? 1168 THR A CB     1 ? 
ATOM   2394 O OG1    . THR A 1 160 ? 29.597  -12.543 0.319   1    17.311 ? 1168 THR A OG1    1 ? 
ATOM   2395 C CG2    . THR A 1 160 ? 27.221  -12.433 0.674   1    16.284 ? 1168 THR A CG2    1 ? 
ATOM   2396 H H      . THR A 1 160 ? 29.69   -15.757 0.76    1    14.563 ? 1168 THR A H      1 ? 
ATOM   2397 H HA     . THR A 1 160 ? 28.924  -13.528 2.596   1    14.807 ? 1168 THR A HA     1 c 
ATOM   2398 H HB     . THR A 1 160 ? 28.285  -14     -0.338  1    16.429 ? 1168 THR A HB     1 c 
ATOM   2399 H HG1    . THR A 1 160 ? 30.345  -13.092 0.073   1    17.238 ? 1168 THR A HG1    1 ? 
ATOM   2400 H HG21   . THR A 1 160 ? 27.326  -11.835 1.582   1    16.441 ? 1168 THR A HG21   1 c 
ATOM   2401 H HG22   . THR A 1 160 ? 27.156  -11.77  -0.191  1    16.441 ? 1168 THR A HG22   1 c 
ATOM   2402 H HG23   . THR A 1 160 ? 26.312  -13.035 0.739   1    16.393 ? 1168 THR A HG23   1 c 
ATOM   2403 N N      . HIS A 1 161 ? 26.706  -14.467 3.213   1    15.846 ? 1169 HIS A N      1 ? 
ATOM   2404 C CA     . HIS A 1 161 ? 25.53   -15.106 3.784   1    14.719 ? 1169 HIS A CA     1 ? 
ATOM   2405 C C      . HIS A 1 161 ? 24.418  -14.064 3.859   1    14.409 ? 1169 HIS A C      1 ? 
ATOM   2406 O O      . HIS A 1 161 ? 24.499  -13.126 4.665   1    16.332 ? 1169 HIS A O      1 ? 
ATOM   2407 C CB     . HIS A 1 161 ? 25.837  -15.652 5.182   1    15.438 ? 1169 HIS A CB     1 ? 
ATOM   2408 C CG     . HIS A 1 161 ? 26.95   -16.641 5.222   1    14.85  ? 1169 HIS A CG     1 ? 
ATOM   2409 N ND1    . HIS A 1 161 ? 26.797  -17.954 4.822   1    14.499 ? 1169 HIS A ND1    1 ? 
ATOM   2410 C CD2    . HIS A 1 161 ? 28.236  -16.507 5.626   1    15.004 ? 1169 HIS A CD2    1 ? 
ATOM   2411 C CE1    . HIS A 1 161 ? 27.95   -18.586 4.992   1    15.807 ? 1169 HIS A CE1    1 ? 
ATOM   2412 N NE2    . HIS A 1 161 ? 28.842  -17.727 5.466   1    14.802 ? 1169 HIS A NE2    1 ? 
ATOM   2413 H H      . HIS A 1 161 ? 27.048  -13.596 3.658   1    14.955 ? 1169 HIS A H      1 ? 
ATOM   2414 H HA     . HIS A 1 161 ? 25.206  -15.918 3.131   1    14.968 ? 1169 HIS A HA     1 c 
ATOM   2415 H HB2    . HIS A 1 161 ? 26.086  -14.814 5.836   1    15.154 ? 1169 HIS A HB2    1 c 
ATOM   2416 H HB3    . HIS A 1 161 ? 24.934  -16.121 5.578   1    15.149 ? 1169 HIS A HB3    1 c 
ATOM   2417 H HD2    . HIS A 1 161 ? 28.706  -15.606 6.007   1    14.945 ? 1169 HIS A HD2    1 c 
ATOM   2418 H HE1    . HIS A 1 161 ? 28.136  -19.629 4.757   1    15.292 ? 1169 HIS A HE1    1 c 
ATOM   2419 H HE2    . HIS A 1 161 ? 29.799  -17.86  5.714   1    15.832 ? 1169 HIS A HE2    1 ? 
ATOM   2420 N N      . ILE A 1 162 ? 23.384  -14.241 3.037   1    12.877 ? 1170 ILE A N      1 ? 
ATOM   2421 C CA     . ILE A 1 162 ? 22.231  -13.348 2.983   1    13.866 ? 1170 ILE A CA     1 ? 
ATOM   2422 C C      . ILE A 1 162 ? 21.103  -14.038 3.742   1    14.116 ? 1170 ILE A C      1 ? 
ATOM   2423 O O      . ILE A 1 162 ? 20.627  -15.099 3.325   1    14.081 ? 1170 ILE A O      1 ? 
ATOM   2424 C CB     . ILE A 1 162 ? 21.827  -13.043 1.534   1    13.617 ? 1170 ILE A CB     1 ? 
ATOM   2425 C CG1    . ILE A 1 162 ? 22.996  -12.431 0.74    1    15.149 ? 1170 ILE A CG1    1 ? 
ATOM   2426 C CG2    . ILE A 1 162 ? 20.608  -12.138 1.521   1    12.557 ? 1170 ILE A CG2    1 ? 
ATOM   2427 C CD1    . ILE A 1 162 ? 22.782  -12.453 -0.769  1    14.641 ? 1170 ILE A CD1    1 ? 
ATOM   2428 H H      . ILE A 1 162 ? 23.383  -15.073 2.414   1    12.669 ? 1170 ILE A H      1 ? 
ATOM   2429 H HA     . ILE A 1 162 ? 22.481  -12.412 3.486   1    13.698 ? 1170 ILE A HA     1 c 
ATOM   2430 H HB     . ILE A 1 162 ? 21.554  -13.986 1.056   1    13.72  ? 1170 ILE A HB     1 c 
ATOM   2431 H HG12   . ILE A 1 162 ? 23.136  -11.397 1.061   1    14.691 ? 1170 ILE A HG12   1 c 
ATOM   2432 H HG13   . ILE A 1 162 ? 23.909  -12.982 0.973   1    14.681 ? 1170 ILE A HG13   1 c 
ATOM   2433 H HG21   . ILE A 1 162 ? 20.813  -11.24  2.107   1    12.857 ? 1170 ILE A HG21   1 c 
ATOM   2434 H HG22   . ILE A 1 162 ? 20.374  -11.854 0.493   1    12.875 ? 1170 ILE A HG22   1 c 
ATOM   2435 H HG23   . ILE A 1 162 ? 19.754  -12.664 1.953   1    12.882 ? 1170 ILE A HG23   1 c 
ATOM   2436 H HD11   . ILE A 1 162 ? 23.651  -12.019 -1.267  1    14.768 ? 1170 ILE A HD11   1 c 
ATOM   2437 H HD12   . ILE A 1 162 ? 22.65   -13.484 -1.104  1    14.768 ? 1170 ILE A HD12   1 c 
ATOM   2438 H HD13   . ILE A 1 162 ? 21.892  -11.874 -1.022  1    14.731 ? 1170 ILE A HD13   1 c 
ATOM   2439 N N      . MET A 1 163 ? 20.691  -13.448 4.869   1    15.825 ? 1171 MET A N      1 ? 
ATOM   2440 C CA     . MET A 1 163 ? 19.81   -14.094 5.845   1    14.372 ? 1171 MET A CA     1 ? 
ATOM   2441 C C      . MET A 1 163 ? 18.458  -13.386 5.809   1    14.323 ? 1171 MET A C      1 ? 
ATOM   2442 O O      . MET A 1 163 ? 18.375  -12.205 6.163   1    14.484 ? 1171 MET A O      1 ? 
ATOM   2443 C CB     . MET A 1 163 ? 20.447  -13.916 7.219   1    15.126 ? 1171 MET A CB     1 ? 
ATOM   2444 C CG     . MET A 1 163 ? 21.819  -14.56  7.293   1    15.81  ? 1171 MET A CG     1 ? 
ATOM   2445 S SD     . MET A 1 163 ? 22.62   -14.241 8.863   1    18.24  ? 1171 MET A SD     1 ? 
ATOM   2446 C CE     . MET A 1 163 ? 24.326  -14.535 8.42    1    21.597 ? 1171 MET A CE     1 ? 
ATOM   2447 H H      . MET A 1 163 ? 20.998  -12.475 5.048   1    14.689 ? 1171 MET A H      1 ? 
ATOM   2448 H HA     . MET A 1 163 ? 19.697  -15.153 5.602   1    14.75  ? 1171 MET A HA     1 c 
ATOM   2449 H HB2    . MET A 1 163 ? 20.536  -12.849 7.435   1    15.091 ? 1171 MET A HB2    1 c 
ATOM   2450 H HB3    . MET A 1 163 ? 19.796  -14.362 7.974   1    15.091 ? 1171 MET A HB3    1 c 
ATOM   2451 H HG2    . MET A 1 163 ? 21.723  -15.639 7.156   1    16.071 ? 1171 MET A HG2    1 c 
ATOM   2452 H HG3    . MET A 1 163 ? 22.449  -14.172 6.49    1    16.07  ? 1171 MET A HG3    1 c 
ATOM   2453 H HE1    . MET A 1 163 ? 24.626  -13.832 7.641   1    20.688 ? 1171 MET A HE1    1 c 
ATOM   2454 H HE2    . MET A 1 163 ? 24.959  -14.396 9.299   1    20.688 ? 1171 MET A HE2    1 c 
ATOM   2455 H HE3    . MET A 1 163 ? 24.436  -15.557 8.051   1    20.526 ? 1171 MET A HE3    1 c 
ATOM   2456 N N      . ILE A 1 164 ? 17.409  -14.102 5.389   1    14.131 ? 1172 ILE A N      1 ? 
ATOM   2457 C CA     . ILE A 1 164 ? 16.066  -13.54  5.229   1    14.894 ? 1172 ILE A CA     1 ? 
ATOM   2458 C C      . ILE A 1 164 ? 15.153  -14.14  6.29    1    14.386 ? 1172 ILE A C      1 ? 
ATOM   2459 O O      . ILE A 1 164 ? 14.809  -15.326 6.221   1    13.712 ? 1172 ILE A O      1 ? 
ATOM   2460 C CB     . ILE A 1 164 ? 15.486  -13.809 3.83    1    15.428 ? 1172 ILE A CB     1 ? 
ATOM   2461 C CG1    . ILE A 1 164 ? 16.477  -13.461 2.709   1    16.159 ? 1172 ILE A CG1    1 ? 
ATOM   2462 C CG2    . ILE A 1 164 ? 14.15   -13.073 3.674   1    17.797 ? 1172 ILE A CG2    1 ? 
ATOM   2463 C CD1    . ILE A 1 164 ? 16.952  -12.034 2.724   1    14.932 ? 1172 ILE A CD1    1 ? 
ATOM   2464 H H      . ILE A 1 164 ? 17.571  -15.078 5.068   1    13.595 ? 1172 ILE A H      1 ? 
ATOM   2465 H HA     . ILE A 1 164 ? 16.118  -12.46  5.381   1    14.758 ? 1172 ILE A HA     1 c 
ATOM   2466 H HB     . ILE A 1 164 ? 15.282  -14.879 3.761   1    15.839 ? 1172 ILE A HB     1 c 
ATOM   2467 H HG12   . ILE A 1 164 ? 17.344  -14.119 2.792   1    15.711 ? 1172 ILE A HG12   1 c 
ATOM   2468 H HG13   . ILE A 1 164 ? 16      -13.66  1.747   1    15.718 ? 1172 ILE A HG13   1 c 
ATOM   2469 H HG21   . ILE A 1 164 ? 13.777  -13.204 2.656   1    17.087 ? 1172 ILE A HG21   1 c 
ATOM   2470 H HG22   . ILE A 1 164 ? 13.421  -13.477 4.38    1    17.075 ? 1172 ILE A HG22   1 c 
ATOM   2471 H HG23   . ILE A 1 164 ? 14.293  -12.008 3.871   1    17.036 ? 1172 ILE A HG23   1 c 
ATOM   2472 H HD11   . ILE A 1 164 ? 17.483  -11.831 3.657   1    15.264 ? 1172 ILE A HD11   1 c 
ATOM   2473 H HD12   . ILE A 1 164 ? 17.626  -11.866 1.882   1    15.269 ? 1172 ILE A HD12   1 c 
ATOM   2474 H HD13   . ILE A 1 164 ? 16.095  -11.362 2.642   1    15.281 ? 1172 ILE A HD13   1 c 
ATOM   2475 N N      . ALA A 1 165 ? 14.732  -13.316 7.258   1    16.112 ? 1173 ALA A N      1 ? 
ATOM   2476 C CA     . ALA A 1 165 ? 13.911  -13.772 8.374   1    16.871 ? 1173 ALA A CA     1 ? 
ATOM   2477 C C      . ALA A 1 165 ? 12.592  -13.009 8.43    1    18.144 ? 1173 ALA A C      1 ? 
ATOM   2478 O O      . ALA A 1 165 ? 12.538  -11.815 8.138   1    16.615 ? 1173 ALA A O      1 ? 
ATOM   2479 C CB     . ALA A 1 165 ? 14.621  -13.525 9.71    1    16.738 ? 1173 ALA A CB     1 ? 
ATOM   2480 H H      . ALA A 1 165 ? 14.967  -12.308 7.193   1    16.125 ? 1173 ALA A H      1 ? 
ATOM   2481 H HA     . ALA A 1 165 ? 13.702  -14.835 8.255   1    16.879 ? 1173 ALA A HA     1 c 
ATOM   2482 H HB1    . ALA A 1 165 ? 15.555  -14.087 9.739   1    16.699 ? 1173 ALA A HB1    1 c 
ATOM   2483 H HB2    . ALA A 1 165 ? 14.837  -12.46  9.821   1    16.754 ? 1173 ALA A HB2    1 c 
ATOM   2484 H HB3    . ALA A 1 165 ? 13.98   -13.85  10.532  1    16.745 ? 1173 ALA A HB3    1 c 
ATOM   2485 N N      . THR A 1 166 ? 11.539  -13.705 8.864   1    19.52  ? 1174 THR A N      1 ? 
ATOM   2486 C CA     . THR A 1 166 ? 10.353  -13.049 9.404   1    21.427 ? 1174 THR A CA     1 ? 
ATOM   2487 C C      . THR A 1 166 ? 10.106  -13.593 10.809  1    18.691 ? 1174 THR A C      1 ? 
ATOM   2488 O O      . THR A 1 166 ? 10.245  -14.795 11.052  1    17.614 ? 1174 THR A O      1 ? 
ATOM   2489 C CB     . THR A 1 166 ? 9.088   -13.221 8.539   1    21.614 ? 1174 THR A CB     1 ? 
ATOM   2490 O OG1    . THR A 1 166 ? 8.774   -14.606 8.387   1    20.954 ? 1174 THR A OG1    1 ? 
ATOM   2491 C CG2    . THR A 1 166 ? 9.298   -12.595 7.168   1    21.933 ? 1174 THR A CG2    1 ? 
ATOM   2492 H H      . THR A 1 166 ? 11.564  -14.74  8.826   1    19.682 ? 1174 THR A H      1 ? 
ATOM   2493 H HA     . THR A 1 166 ? 10.566  -11.984 9.483   1    20.495 ? 1174 THR A HA     1 c 
ATOM   2494 H HB     . THR A 1 166 ? 8.251   -12.717 9.026   1    21.51  ? 1174 THR A HB     1 c 
ATOM   2495 H HG1    . THR A 1 166 ? 9.355   -15.134 7.829   1    23.458 ? 1174 THR A HG1    1 ? 
ATOM   2496 H HG21   . THR A 1 166 ? 9.509   -11.53  7.282   1    21.842 ? 1174 THR A HG21   1 c 
ATOM   2497 H HG22   . THR A 1 166 ? 10.139  -13.081 6.67    1    21.842 ? 1174 THR A HG22   1 c 
ATOM   2498 H HG23   . THR A 1 166 ? 8.396   -12.724 6.566   1    21.836 ? 1174 THR A HG23   1 c 
ATOM   2499 N N      . GLY A 1 167 ? 9.771   -12.689 11.725  1    18.956 ? 1175 GLY A N      1 ? 
ATOM   2500 C CA     . GLY A 1 167 ? 9.425   -13.082 13.083  1    20.546 ? 1175 GLY A CA     1 ? 
ATOM   2501 C C      . GLY A 1 167 ? 10.48   -13.988 13.705  1    20.313 ? 1175 GLY A C      1 ? 
ATOM   2502 O O      . GLY A 1 167 ? 11.684  -13.698 13.679  1    17.492 ? 1175 GLY A O      1 ? 
ATOM   2503 H H      . GLY A 1 167 ? 9.922   -11.685 11.515  1    17.785 ? 1175 GLY A H      1 ? 
ATOM   2504 H HA2    . GLY A 1 167 ? 9.315   -12.183 13.693  1    20.13  ? 1175 GLY A HA2    1 c 
ATOM   2505 H HA3    . GLY A 1 167 ? 8.463   -13.597 13.072  1    20.161 ? 1175 GLY A HA3    1 c 
ATOM   2506 N N      . THR A 1 168 ? 10.013  -15.104 14.279  1    20.288 ? 1176 THR A N      1 ? 
ATOM   2507 C CA     . THR A 1 168 ? 10.888  -16.034 14.979  1    19.212 ? 1176 THR A CA     1 ? 
ATOM   2508 C C      . THR A 1 168 ? 11.91   -16.701 14.061  1    17.023 ? 1176 THR A C      1 ? 
ATOM   2509 O O      . THR A 1 168 ? 12.846  -17.329 14.566  1    16.42  ? 1176 THR A O      1 ? 
ATOM   2510 C CB     . THR A 1 168 ? 10.076  -17.098 15.732  1    18.256 ? 1176 THR A CB     1 ? 
ATOM   2511 O OG1    . THR A 1 168 ? 9.196   -17.77  14.827  1    18.508 ? 1176 THR A OG1    1 ? 
ATOM   2512 C CG2    . THR A 1 168 ? 9.265   -16.481 16.86   1    16.382 ? 1176 THR A CG2    1 ? 
ATOM   2513 H H      . THR A 1 168 ? 9.017   -15.352 14.126  1    20.857 ? 1176 THR A H      1 ? 
ATOM   2514 H HA     . THR A 1 168 ? 11.441  -15.457 15.724  1    18.826 ? 1176 THR A HA     1 c 
ATOM   2515 H HB     . THR A 1 168 ? 10.764  -17.827 16.164  1    18.114 ? 1176 THR A HB     1 c 
ATOM   2516 H HG1    . THR A 1 168 ? 9.715   -18.417 14.288  1    19.004 ? 1176 THR A HG1    1 ? 
ATOM   2517 H HG21   . THR A 1 168 ? 8.573   -15.743 16.451  1    16.898 ? 1176 THR A HG21   1 c 
ATOM   2518 H HG22   . THR A 1 168 ? 8.701   -17.263 17.373  1    16.898 ? 1176 THR A HG22   1 c 
ATOM   2519 H HG23   . THR A 1 168 ? 9.938   -15.994 17.569  1    16.944 ? 1176 THR A HG23   1 c 
ATOM   2520 N N      . GLY A 1 169 ? 11.756  -16.577 12.742  1    14.545 ? 1177 GLY A N      1 ? 
ATOM   2521 C CA     . GLY A 1 169 ? 12.777  -17.034 11.814  1    15.26  ? 1177 GLY A CA     1 ? 
ATOM   2522 C C      . GLY A 1 169 ? 14.123  -16.348 11.992  1    14.703 ? 1177 GLY A C      1 ? 
ATOM   2523 O O      . GLY A 1 169 ? 15.118  -16.816 11.423  1    16.692 ? 1177 GLY A O      1 ? 
ATOM   2524 H H      . GLY A 1 169 ? 11.003  -15.958 12.409  1    16.138 ? 1177 GLY A H      1 ? 
ATOM   2525 H HA2    . GLY A 1 169 ? 12.907  -18.11  11.939  1    14.984 ? 1177 GLY A HA2    1 c 
ATOM   2526 H HA3    . GLY A 1 169 ? 12.424  -16.864 10.801  1    15.039 ? 1177 GLY A HA3    1 c 
ATOM   2527 N N      . VAL A 1 170 ? 14.183  -15.27  12.778  1    13.803 ? 1178 VAL A N      1 ? 
ATOM   2528 C CA     . VAL A 1 170 ? 15.467  -14.663 13.09   1    15.599 ? 1178 VAL A CA     1 ? 
ATOM   2529 C C      . VAL A 1 170 ? 16.359  -15.589 13.913  1    13.82  ? 1178 VAL A C      1 ? 
ATOM   2530 O O      . VAL A 1 170 ? 17.58   -15.385 13.957  1    14.012 ? 1178 VAL A O      1 ? 
ATOM   2531 C CB     . VAL A 1 170 ? 15.239  -13.322 13.818  1    15.501 ? 1178 VAL A CB     1 ? 
ATOM   2532 C CG1    . VAL A 1 170 ? 14.884  -13.548 15.294  1    16.489 ? 1178 VAL A CG1    1 ? 
ATOM   2533 C CG2    . VAL A 1 170 ? 16.443  -12.417 13.663  1    15.8   ? 1178 VAL A CG2    1 ? 
ATOM   2534 H H      . VAL A 1 170 ? 13.311  -14.82  13.115  1    14.14  ? 1178 VAL A H      1 ? 
ATOM   2535 H HA     . VAL A 1 170 ? 15.976  -14.453 12.147  1    14.899 ? 1178 VAL A HA     1 c 
ATOM   2536 H HB     . VAL A 1 170 ? 14.388  -12.835 13.338  1    15.745 ? 1178 VAL A HB     1 c 
ATOM   2537 H HG11   . VAL A 1 170 ? 14.052  -14.252 15.366  1    16.204 ? 1178 VAL A HG11   1 c 
ATOM   2538 H HG12   . VAL A 1 170 ? 15.749  -13.952 15.822  1    16.193 ? 1178 VAL A HG12   1 c 
ATOM   2539 H HG13   . VAL A 1 170 ? 14.596  -12.598 15.748  1    16.196 ? 1178 VAL A HG13   1 c 
ATOM   2540 H HG21   . VAL A 1 170 ? 16.243  -11.459 14.147  1    15.719 ? 1178 VAL A HG21   1 c 
ATOM   2541 H HG22   . VAL A 1 170 ? 17.313  -12.884 14.128  1    15.705 ? 1178 VAL A HG22   1 c 
ATOM   2542 H HG23   . VAL A 1 170 ? 16.642  -12.253 12.602  1    15.711 ? 1178 VAL A HG23   1 c 
ATOM   2543 N N      . ALA A 1 171 ? 15.78   -16.599 14.57   1    13.474 ? 1179 ALA A N      1 ? 
ATOM   2544 C CA     . ALA A 1 171 ? 16.494  -17.425 15.54   1    14.481 ? 1179 ALA A CA     1 ? 
ATOM   2545 C C      . ALA A 1 171 ? 17.837  -17.984 15.04   1    13.575 ? 1179 ALA A C      1 ? 
ATOM   2546 O O      . ALA A 1 171 ? 18.865  -17.745 15.689  1    13.373 ? 1179 ALA A O      1 ? 
ATOM   2547 C CB     . ALA A 1 171 ? 15.579  -18.534 16.05   1    14.302 ? 1179 ALA A CB     1 ? 
ATOM   2548 H H      . ALA A 1 171 ? 14.747  -16.712 14.513  1    12.979 ? 1179 ALA A H      1 ? 
ATOM   2549 H HA     . ALA A 1 171 ? 16.724  -16.778 16.389  1    14.089 ? 1179 ALA A HA     1 c 
ATOM   2550 H HB1    . ALA A 1 171 ? 15.245  -19.15  15.212  1    14.345 ? 1179 ALA A HB1    1 c 
ATOM   2551 H HB2    . ALA A 1 171 ? 16.121  -19.159 16.763  1    14.345 ? 1179 ALA A HB2    1 c 
ATOM   2552 H HB3    . ALA A 1 171 ? 14.709  -18.095 16.543  1    14.325 ? 1179 ALA A HB3    1 c 
ATOM   2553 N N      . PRO A 1 172 ? 17.901  -18.749 13.935  1    14.495 ? 1180 PRO A N      1 ? 
ATOM   2554 C CA     . PRO A 1 172 ? 19.2    -19.283 13.534  1    13.089 ? 1180 PRO A CA     1 ? 
ATOM   2555 C C      . PRO A 1 172 ? 20.206  -18.183 13.24   1    13.429 ? 1180 PRO A C      1 ? 
ATOM   2556 O O      . PRO A 1 172 ? 21.406  -18.364 13.459  1    13.526 ? 1180 PRO A O      1 ? 
ATOM   2557 C CB     . PRO A 1 172 ? 18.896  -20.103 12.277  1    13.793 ? 1180 PRO A CB     1 ? 
ATOM   2558 C CG     . PRO A 1 172 ? 17.609  -19.492 11.741  1    13.995 ? 1180 PRO A CG     1 ? 
ATOM   2559 C CD     . PRO A 1 172 ? 16.838  -19.147 12.988  1    14.244 ? 1180 PRO A CD     1 ? 
ATOM   2560 H HA     . PRO A 1 172 ? 19.587  -19.934 14.32   1    13.525 ? 1180 PRO A HA     1 c 
ATOM   2561 H HB2    . PRO A 1 172 ? 19.704  -20.014 11.547  1    13.682 ? 1180 PRO A HB2    1 c 
ATOM   2562 H HB3    . PRO A 1 172 ? 18.755  -21.157 12.523  1    13.682 ? 1180 PRO A HB3    1 c 
ATOM   2563 H HG2    . PRO A 1 172 ? 17.813  -18.597 11.149  1    14.005 ? 1180 PRO A HG2    1 c 
ATOM   2564 H HG3    . PRO A 1 172 ? 17.057  -20.208 11.128  1    14.005 ? 1180 PRO A HG3    1 c 
ATOM   2565 H HD2    . PRO A 1 172 ? 16.146  -18.325 12.814  1    14.256 ? 1180 PRO A HD2    1 c 
ATOM   2566 H HD3    . PRO A 1 172 ? 16.287  -20.01  13.366  1    14.247 ? 1180 PRO A HD3    1 c 
ATOM   2567 N N      . PHE A 1 173 ? 19.724  -17.04  12.74   1    14.07  ? 1181 PHE A N      1 ? 
ATOM   2568 C CA     . PHE A 1 173 ? 20.62   -15.961 12.368  1    14     ? 1181 PHE A CA     1 ? 
ATOM   2569 C C      . PHE A 1 173 ? 21.227  -15.272 13.589  1    13.339 ? 1181 PHE A C      1 ? 
ATOM   2570 O O      . PHE A 1 173 ? 22.366  -14.796 13.525  1    10.707 ? 1181 PHE A O      1 ? 
ATOM   2571 C CB     . PHE A 1 173 ? 19.88   -14.983 11.455  1    13.871 ? 1181 PHE A CB     1 ? 
ATOM   2572 C CG     . PHE A 1 173 ? 19.222  -15.661 10.283  1    13.405 ? 1181 PHE A CG     1 ? 
ATOM   2573 C CD1    . PHE A 1 173 ? 19.844  -16.721 9.628   1    13.046 ? 1181 PHE A CD1    1 ? 
ATOM   2574 C CD2    . PHE A 1 173 ? 17.968  -15.259 9.847   1    14.857 ? 1181 PHE A CD2    1 ? 
ATOM   2575 C CE1    . PHE A 1 173 ? 19.241  -17.362 8.559   1    13.313 ? 1181 PHE A CE1    1 ? 
ATOM   2576 C CE2    . PHE A 1 173 ? 17.36   -15.897 8.765   1    14.11  ? 1181 PHE A CE2    1 ? 
ATOM   2577 C CZ     . PHE A 1 173 ? 17.994  -16.948 8.121   1    14.309 ? 1181 PHE A CZ     1 ? 
ATOM   2578 H H      . PHE A 1 173 ? 18.698  -16.899 12.674  1    14.25  ? 1181 PHE A H      1 ? 
ATOM   2579 H HA     . PHE A 1 173 ? 21.44   -16.396 11.794  1    13.858 ? 1181 PHE A HA     1 c 
ATOM   2580 H HB2    . PHE A 1 173 ? 19.118  -14.465 12.042  1    13.795 ? 1181 PHE A HB2    1 c 
ATOM   2581 H HB3    . PHE A 1 173 ? 20.591  -14.242 11.086  1    13.795 ? 1181 PHE A HB3    1 c 
ATOM   2582 H HD1    . PHE A 1 173 ? 20.82   -17.052 9.963   1    13.223 ? 1181 PHE A HD1    1 c 
ATOM   2583 H HD2    . PHE A 1 173 ? 17.465  -14.437 10.344  1    14.37  ? 1181 PHE A HD2    1 c 
ATOM   2584 H HE1    . PHE A 1 173 ? 19.749  -18.181 8.06    1    13.477 ? 1181 PHE A HE1    1 c 
ATOM   2585 H HE2    . PHE A 1 173 ? 16.382  -15.57  8.428   1    14.316 ? 1181 PHE A HE2    1 c 
ATOM   2586 H HZ     . PHE A 1 173 ? 17.517  -17.442 7.281   1    14.037 ? 1181 PHE A HZ     1 c 
ATOM   2587 N N      . ARG A 1 174 ? 20.493  -15.208 14.708  1    13.997 ? 1182 ARG A N      1 ? 
ATOM   2588 C CA     . ARG A 1 174 ? 21.122  -14.74  15.94   1    12.72  ? 1182 ARG A CA     1 ? 
ATOM   2589 C C      . ARG A 1 174 ? 22.343  -15.604 16.276  1    12.87  ? 1182 ARG A C      1 ? 
ATOM   2590 O O      . ARG A 1 174 ? 23.41   -15.084 16.646  1    14.779 ? 1182 ARG A O      1 ? 
ATOM   2591 C CB     . ARG A 1 174 ? 20.115  -14.753 17.091  1    13.249 ? 1182 ARG A CB     1 ? 
ATOM   2592 C CG     . ARG A 1 174 ? 20.71   -14.214 18.394  1    13.652 ? 1182 ARG A CG     1 ? 
ATOM   2593 C CD     . ARG A 1 174 ? 19.651  -14.192 19.494  1    13.247 ? 1182 ARG A CD     1 ? 
ATOM   2594 N NE     . ARG A 1 174 ? 20.137  -13.662 20.766  1    13.915 ? 1182 ARG A NE     1 ? 
ATOM   2595 C CZ     . ARG A 1 174 ? 20.651  -14.405 21.738  1    14.737 ? 1182 ARG A CZ     1 ? 
ATOM   2596 N NH1    . ARG A 1 174 ? 20.796  -15.721 21.602  1    16.479 ? 1182 ARG A NH1    1 ? 
ATOM   2597 N NH2    . ARG A 1 174 ? 21.007  -13.823 22.877  1    15.356 ? 1182 ARG A NH2    1 ? 
ATOM   2598 H H      . ARG A 1 174 ? 19.493  -15.489 14.743  1    14.029 ? 1182 ARG A H      1 ? 
ATOM   2599 H HA     . ARG A 1 174 ? 21.458  -13.713 15.781  1    13.072 ? 1182 ARG A HA     1 c 
ATOM   2600 H HB2    . ARG A 1 174 ? 19.25   -14.145 16.817  1    13.218 ? 1182 ARG A HB2    1 c 
ATOM   2601 H HB3    . ARG A 1 174 ? 19.77   -15.776 17.253  1    13.218 ? 1182 ARG A HB3    1 c 
ATOM   2602 H HG2    . ARG A 1 174 ? 21.541  -14.849 18.709  1    13.472 ? 1182 ARG A HG2    1 c 
ATOM   2603 H HG3    . ARG A 1 174 ? 21.086  -13.202 18.234  1    13.474 ? 1182 ARG A HG3    1 c 
ATOM   2604 H HD2    . ARG A 1 174 ? 18.816  -13.577 19.152  1    13.499 ? 1182 ARG A HD2    1 c 
ATOM   2605 H HD3    . ARG A 1 174 ? 19.269  -15.202 19.647  1    13.516 ? 1182 ARG A HD3    1 c 
ATOM   2606 H HE     . ARG A 1 174 ? 20.205  -12.649 20.873  0.5  11.501 ? 1182 ARG A HE     1 ? 
ATOM   2607 H HH11   . ARG A 1 174 ? 20.629  -16.201 20.696  1    16.821 ? 1182 ARG A HH11   1 ? 
ATOM   2608 H HH12   . ARG A 1 174 ? 21.118  -16.259 22.397  1    16.092 ? 1182 ARG A HH12   1 ? 
ATOM   2609 H HH21   . ARG A 1 174 ? 20.806  -12.864 23.026  1    15.432 ? 1182 ARG A HH21   1 ? 
ATOM   2610 H HH22   . ARG A 1 174 ? 21.474  -14.4   23.563  1    15.36  ? 1182 ARG A HH22   1 ? 
ATOM   2611 N N      . GLY A 1 175 ? 22.204  -16.921 16.116  1    13.485 ? 1183 GLY A N      1 ? 
ATOM   2612 C CA     . GLY A 1 175 ? 23.313  -17.831 16.352  1    13.432 ? 1183 GLY A CA     1 ? 
ATOM   2613 C C      . GLY A 1 175 ? 24.445  -17.651 15.343  1    14.4   ? 1183 GLY A C      1 ? 
ATOM   2614 O O      . GLY A 1 175 ? 25.621  -17.581 15.725  1    17.029 ? 1183 GLY A O      1 ? 
ATOM   2615 H H      . GLY A 1 175 ? 21.271  -17.29  15.857  1    13.833 ? 1183 GLY A H      1 ? 
ATOM   2616 H HA2    . GLY A 1 175 ? 23.697  -17.669 17.361  1    13.659 ? 1183 GLY A HA2    1 c 
ATOM   2617 H HA3    . GLY A 1 175 ? 22.941  -18.856 16.295  1    13.713 ? 1183 GLY A HA3    1 c 
ATOM   2618 N N      . TYR A 1 176 ? 24.108  -17.588 14.046  1    12.944 ? 1184 TYR A N      1 ? 
ATOM   2619 C CA     . TYR A 1 176 ? 25.144  -17.377 13.037  1    13.232 ? 1184 TYR A CA     1 ? 
ATOM   2620 C C      . TYR A 1 176 ? 25.955  -16.129 13.367  1    12.11  ? 1184 TYR A C      1 ? 
ATOM   2621 O O      . TYR A 1 176 ? 27.188  -16.134 13.315  1    10.399 ? 1184 TYR A O      1 ? 
ATOM   2622 C CB     . TYR A 1 176 ? 24.551  -17.123 11.649  1    13.014 ? 1184 TYR A CB     1 ? 
ATOM   2623 C CG     . TYR A 1 176 ? 23.851  -18.243 10.915  1    13.461 ? 1184 TYR A CG     1 ? 
ATOM   2624 C CD1    . TYR A 1 176 ? 23.73   -19.534 11.415  1    14.47  ? 1184 TYR A CD1    1 ? 
ATOM   2625 C CD2    . TYR A 1 176 ? 23.302  -17.973 9.672   1    13.812 ? 1184 TYR A CD2    1 ? 
ATOM   2626 C CE1    . TYR A 1 176 ? 23.071  -20.521 10.681  1    14.188 ? 1184 TYR A CE1    1 ? 
ATOM   2627 C CE2    . TYR A 1 176 ? 22.632  -18.931 8.958   1    14.661 ? 1184 TYR A CE2    1 ? 
ATOM   2628 C CZ     . TYR A 1 176 ? 22.497  -20.203 9.457   1    14.6   ? 1184 TYR A CZ     1 ? 
ATOM   2629 O OH     . TYR A 1 176 ? 21.821  -21.13  8.702   1    14.692 ? 1184 TYR A OH     1 ? 
ATOM   2630 H H      . TYR A 1 176 ? 23.127  -17.764 13.775  1    13.182 ? 1184 TYR A H      1 ? 
ATOM   2631 H HA     . TYR A 1 176 ? 25.804  -18.247 13.002  1    12.935 ? 1184 TYR A HA     1 c 
ATOM   2632 H HB2    . TYR A 1 176 ? 23.846  -16.294 11.741  1    13.158 ? 1184 TYR A HB2    1 c 
ATOM   2633 H HB3    . TYR A 1 176 ? 25.359  -16.76  11.01   1    13.153 ? 1184 TYR A HB3    1 c 
ATOM   2634 H HD1    . TYR A 1 176 ? 24.159  -19.781 12.38   1    14.174 ? 1184 TYR A HD1    1 c 
ATOM   2635 H HD2    . TYR A 1 176 ? 23.374  -16.969 9.269   1    14.032 ? 1184 TYR A HD2    1 c 
ATOM   2636 H HE1    . TYR A 1 176 ? 22.964  -21.522 11.087  1    14.332 ? 1184 TYR A HE1    1 c 
ATOM   2637 H HE2    . TYR A 1 176 ? 22.198  -18.682 7.996   1    14.446 ? 1184 TYR A HE2    1 c 
ATOM   2638 H HH     . TYR A 1 176 ? 21.85   -21.966 9.142   1    13.592 ? 1184 TYR A HH     1 ? 
ATOM   2639 N N      . LEU A 1 177 ? 25.249  -15.031 13.659  1    11.789 ? 1185 LEU A N      1 ? 
ATOM   2640 C CA     . LEU A 1 177 ? 25.901  -13.737 13.758  1    12.676 ? 1185 LEU A CA     1 ? 
ATOM   2641 C C      . LEU A 1 177 ? 26.746  -13.633 15.025  1    12.826 ? 1185 LEU A C      1 ? 
ATOM   2642 O O      . LEU A 1 177 ? 27.806  -13.006 15.013  1    13.037 ? 1185 LEU A O      1 ? 
ATOM   2643 C CB     . LEU A 1 177 ? 24.867  -12.62  13.668  1    13.083 ? 1185 LEU A CB     1 ? 
ATOM   2644 C CG     . LEU A 1 177 ? 24.223  -12.474 12.292  1    14.209 ? 1185 LEU A CG     1 ? 
ATOM   2645 C CD1    . LEU A 1 177 ? 22.968  -11.617 12.365  1    14.358 ? 1185 LEU A CD1    1 ? 
ATOM   2646 C CD2    . LEU A 1 177 ? 25.209  -11.906 11.264  1    14.291 ? 1185 LEU A CD2    1 ? 
ATOM   2647 H H      . LEU A 1 177 ? 24.213  -15.079 13.722  1    11.669 ? 1185 LEU A H      1 ? 
ATOM   2648 H HA     . LEU A 1 177 ? 26.579  -13.648 12.907  1    12.605 ? 1185 LEU A HA     1 c 
ATOM   2649 H HB2    . LEU A 1 177 ? 24.083  -12.816 14.402  1    13.233 ? 1185 LEU A HB2    1 c 
ATOM   2650 H HB3    . LEU A 1 177 ? 25.356  -11.678 13.924  1    13.249 ? 1185 LEU A HB3    1 c 
ATOM   2651 H HG     . LEU A 1 177 ? 23.927  -13.469 11.953  1    14.019 ? 1185 LEU A HG     1 c 
ATOM   2652 H HD11   . LEU A 1 177 ? 22.247  -12.081 13.04   1    14.311 ? 1185 LEU A HD11   1 c 
ATOM   2653 H HD12   . LEU A 1 177 ? 23.225  -10.623 12.737  1    14.311 ? 1185 LEU A HD12   1 c 
ATOM   2654 H HD13   . LEU A 1 177 ? 22.528  -11.528 11.369  1    14.294 ? 1185 LEU A HD13   1 c 
ATOM   2655 H HD21   . LEU A 1 177 ? 24.707  -11.792 10.301  1    14.256 ? 1185 LEU A HD21   1 c 
ATOM   2656 H HD22   . LEU A 1 177 ? 25.57   -10.933 11.603  1    14.256 ? 1185 LEU A HD22   1 c 
ATOM   2657 H HD23   . LEU A 1 177 ? 26.055  -12.588 11.154  1    14.22  ? 1185 LEU A HD23   1 c 
ATOM   2658 N N      . ARG A 1 178 ? 26.309  -14.254 16.118  1    15.125 ? 1186 ARG A N      1 ? 
ATOM   2659 C CA     . ARG A 1 178 ? 27.174  -14.274 17.292  1    14.032 ? 1186 ARG A CA     1 ? 
ATOM   2660 C C      . ARG A 1 178 ? 28.455  -15.056 17.014  1    14.035 ? 1186 ARG A C      1 ? 
ATOM   2661 O O      . ARG A 1 178 ? 29.536  -14.66  17.451  1    14.85  ? 1186 ARG A O      1 ? 
ATOM   2662 C CB     . ARG A 1 178 ? 26.442  -14.853 18.503  1    13.745 ? 1186 ARG A CB     1 ? 
ATOM   2663 C CG     . ARG A 1 178 ? 25.545  -13.886 19.223  1    13.519 ? 1186 ARG A CG     1 ? 
ATOM   2664 C CD     . ARG A 1 178 ? 25.12   -14.436 20.576  1    14.594 ? 1186 ARG A CD     1 ? 
ATOM   2665 N NE     . ARG A 1 178 ? 24.402  -13.408 21.32   1    14.194 ? 1186 ARG A NE     1 ? 
ATOM   2666 C CZ     . ARG A 1 178 ? 24.465  -13.234 22.631  1    14.849 ? 1186 ARG A CZ     1 ? 
ATOM   2667 N NH1    . ARG A 1 178 ? 25.116  -14.085 23.415  1    15.769 ? 1186 ARG A NH1    1 ? 
ATOM   2668 N NH2    . ARG A 1 178 ? 23.869  -12.178 23.169  1    16.593 ? 1186 ARG A NH2    1 ? 
ATOM   2669 H H      . ARG A 1 178 ? 25.423  -14.785 16.123  1    13.969 ? 1186 ARG A H      1 ? 
ATOM   2670 H HA     . ARG A 1 178 ? 27.448  -13.243 17.526  1    14.174 ? 1186 ARG A HA     1 c 
ATOM   2671 H HB2    . ARG A 1 178 ? 25.841  -15.702 18.17   1    13.742 ? 1186 ARG A HB2    1 c 
ATOM   2672 H HB3    . ARG A 1 178 ? 27.184  -15.232 19.209  1    13.753 ? 1186 ARG A HB3    1 c 
ATOM   2673 H HG2    . ARG A 1 178 ? 26.071  -12.94  19.368  1    13.806 ? 1186 ARG A HG2    1 c 
ATOM   2674 H HG3    . ARG A 1 178 ? 24.656  -13.697 18.619  1    13.848 ? 1186 ARG A HG3    1 c 
ATOM   2675 H HD2    . ARG A 1 178 ? 24.475  -15.306 20.44   1    14.274 ? 1186 ARG A HD2    1 c 
ATOM   2676 H HD3    . ARG A 1 178 ? 26.004  -14.744 21.138  1    14.305 ? 1186 ARG A HD3    1 c 
ATOM   2677 H HE     . ARG A 1 178 ? 23.732  -12.805 20.839  1    14.716 ? 1186 ARG A HE     1 ? 
ATOM   2678 H HH11   . ARG A 1 178 ? 25.581  -14.916 23.117  1    15.442 ? 1186 ARG A HH11   1 ? 
ATOM   2679 H HH12   . ARG A 1 178 ? 25.091  -13.896 24.406  1    16.599 ? 1186 ARG A HH12   1 ? 
ATOM   2680 H HH21   . ARG A 1 178 ? 23.423  -11.497 22.579  1    17.099 ? 1186 ARG A HH21   1 ? 
ATOM   2681 H HH22   . ARG A 1 178 ? 23.893  -12.012 24.159  1    17.707 ? 1186 ARG A HH22   1 ? 
ATOM   2682 N N      . ARG A 1 179 ? 28.348  -16.177 16.293  1    13.215 ? 1187 ARG A N      1 ? 
ATOM   2683 C CA     . ARG A 1 179 ? 29.533  -16.941 15.944  1    13.498 ? 1187 ARG A CA     1 ? 
ATOM   2684 C C      . ARG A 1 179 ? 30.441  -16.152 14.992  1    13.9   ? 1187 ARG A C      1 ? 
ATOM   2685 O O      . ARG A 1 179 ? 31.671  -16.196 15.123  1    12.672 ? 1187 ARG A O      1 ? 
ATOM   2686 C CB     . ARG A 1 179 ? 29.124  -18.285 15.345  1    12.83  ? 1187 ARG A CB     1 ? 
ATOM   2687 C CG     . ARG A 1 179 ? 30.292  -19.17  14.971  1    12.643 ? 1187 ARG A CG     1 ? 
ATOM   2688 C CD     . ARG A 1 179 ? 29.802  -20.576 14.663  1    13.972 ? 1187 ARG A CD     1 ? 
ATOM   2689 N NE     . ARG A 1 179 ? 30.844  -21.495 14.206  1    14.417 ? 1187 ARG A NE     1 ? 
ATOM   2690 C CZ     . ARG A 1 179 ? 31.655  -22.182 14.996  1    15.01  ? 1187 ARG A CZ     1 ? 
ATOM   2691 N NH1    . ARG A 1 179 ? 31.63   -22.039 16.314  1    16.442 ? 1187 ARG A NH1    1 ? 
ATOM   2692 N NH2    . ARG A 1 179 ? 32.508  -23.04  14.453  1    15.116 ? 1187 ARG A NH2    1 ? 
ATOM   2693 H H      . ARG A 1 179 ? 27.429  -16.526 15.959  1    12.938 ? 1187 ARG A H      1 ? 
ATOM   2694 H HA     . ARG A 1 179 ? 30.09   -17.136 16.863  1    13.4   ? 1187 ARG A HA     1 c 
ATOM   2695 H HB2    . ARG A 1 179 ? 28.499  -18.815 16.067  1    12.931 ? 1187 ARG A HB2    1 c 
ATOM   2696 H HB3    . ARG A 1 179 ? 28.521  -18.104 14.453  1    12.931 ? 1187 ARG A HB3    1 c 
ATOM   2697 H HG2    . ARG A 1 179 ? 30.796  -18.762 14.093  1    12.967 ? 1187 ARG A HG2    1 c 
ATOM   2698 H HG3    . ARG A 1 179 ? 31.004  -19.208 15.799  1    12.963 ? 1187 ARG A HG3    1 c 
ATOM   2699 H HD2    . ARG A 1 179 ? 29.337  -20.985 15.561  1    13.822 ? 1187 ARG A HD2    1 c 
ATOM   2700 H HD3    . ARG A 1 179 ? 29.028  -20.508 13.895  1    13.814 ? 1187 ARG A HD3    1 c 
ATOM   2701 H HE     . ARG A 1 179 ? 30.794  -21.808 13.242  1    13.627 ? 1187 ARG A HE     1 ? 
ATOM   2702 H HH11   . ARG A 1 179 ? 31.037  -21.368 16.775  1    17.109 ? 1187 ARG A HH11   1 ? 
ATOM   2703 H HH12   . ARG A 1 179 ? 32.212  -22.654 16.865  1    16.565 ? 1187 ARG A HH12   1 ? 
ATOM   2704 H HH21   . ARG A 1 179 ? 32.467  -23.27  13.498  1    15.208 ? 1187 ARG A HH21   1 ? 
ATOM   2705 H HH22   . ARG A 1 179 ? 33.112  -23.501 15.078  1    16.575 ? 1187 ARG A HH22   1 ? 
ATOM   2706 N N      . MET A 1 180 ? 29.844  -15.428 14.047  1    13.203 ? 1188 MET A N      1 ? 
ATOM   2707 C CA     . MET A 1 180 ? 30.626  -14.652 13.098  1    13.192 ? 1188 MET A CA     1 ? 
ATOM   2708 C C      . MET A 1 180 ? 31.326  -13.461 13.741  1    13.123 ? 1188 MET A C      1 ? 
ATOM   2709 O O      . MET A 1 180 ? 32.46   -13.141 13.373  1    14.074 ? 1188 MET A O      1 ? 
ATOM   2710 C CB     . MET A 1 180 ? 29.778  -14.139 11.935  1    13.915 ? 1188 MET A CB     1 ? 
ATOM   2711 C CG     . MET A 1 180 ? 29.33   -15.189 10.984  1    14.278 ? 1188 MET A CG     1 ? 
ATOM   2712 S SD     . MET A 1 180 ? 27.956  -14.626 9.974   1    13.998 ? 1188 MET A SD     1 ? 
ATOM   2713 C CE     . MET A 1 180 ? 27.622  -16.161 9.112   1    13.262 ? 1188 MET A CE     1 ? 
ATOM   2714 H H      . MET A 1 180 ? 28.812  -15.377 13.986  1    12.807 ? 1188 MET A H      1 ? 
ATOM   2715 H HA     . MET A 1 180 ? 31.401  -15.31  12.699  1    13.303 ? 1188 MET A HA     1 c 
ATOM   2716 H HB2    . MET A 1 180 ? 28.898  -13.638 12.345  1    13.834 ? 1188 MET A HB2    1 c 
ATOM   2717 H HB3    . MET A 1 180 ? 30.357  -13.392 11.388  1    13.834 ? 1188 MET A HB3    1 c 
ATOM   2718 H HG2    . MET A 1 180 ? 30.16   -15.467 10.331  1    14.136 ? 1188 MET A HG2    1 c 
ATOM   2719 H HG3    . MET A 1 180 ? 29.023  -16.077 11.538  1    14.115 ? 1188 MET A HG3    1 c 
ATOM   2720 H HE1    . MET A 1 180 ? 26.786  -16.017 8.424   1    13.438 ? 1188 MET A HE1    1 c 
ATOM   2721 H HE2    . MET A 1 180 ? 28.508  -16.463 8.55    1    13.438 ? 1188 MET A HE2    1 c 
ATOM   2722 H HE3    . MET A 1 180 ? 27.368  -16.937 9.837   1    13.455 ? 1188 MET A HE3    1 c 
ATOM   2723 N N      . PHE A 1 181 ? 30.658  -12.781 14.671  1    15.201 ? 1189 PHE A N      1 ? 
ATOM   2724 C CA     . PHE A 1 181 ? 31.106  -11.471 15.124  1    14.643 ? 1189 PHE A CA     1 ? 
ATOM   2725 C C      . PHE A 1 181 ? 31.374  -11.363 16.619  1    15.852 ? 1189 PHE A C      1 ? 
ATOM   2726 O O      . PHE A 1 181 ? 32.294  -10.624 17.007  1    16.656 ? 1189 PHE A O      1 ? 
ATOM   2727 C CB     . PHE A 1 181 ? 30.076  -10.409 14.722  1    14.605 ? 1189 PHE A CB     1 ? 
ATOM   2728 C CG     . PHE A 1 181 ? 29.936  -10.265 13.231  1    14.524 ? 1189 PHE A CG     1 ? 
ATOM   2729 C CD1    . PHE A 1 181 ? 31.046  -10.062 12.432  1    16.512 ? 1189 PHE A CD1    1 ? 
ATOM   2730 C CD2    . PHE A 1 181 ? 28.696  -10.387 12.625  1    16.25  ? 1189 PHE A CD2    1 ? 
ATOM   2731 C CE1    . PHE A 1 181 ? 30.924  -9.95   11.055  1    18.93  ? 1189 PHE A CE1    1 ? 
ATOM   2732 C CE2    . PHE A 1 181 ? 28.57   -10.278 11.25   1    16.206 ? 1189 PHE A CE2    1 ? 
ATOM   2733 C CZ     . PHE A 1 181 ? 29.684  -10.062 10.463  1    16.636 ? 1189 PHE A CZ     1 ? 
ATOM   2734 H H      . PHE A 1 181 ? 29.72   -13.105 14.951  1    14.734 ? 1189 PHE A H      1 ? 
ATOM   2735 H HA     . PHE A 1 181 ? 32.039  -11.241 14.606  1    14.953 ? 1189 PHE A HA     1 c 
ATOM   2736 H HB2    . PHE A 1 181 ? 29.107  -10.683 15.146  1    14.604 ? 1189 PHE A HB2    1 c 
ATOM   2737 H HB3    . PHE A 1 181 ? 30.377  -9.45   15.147  1    14.639 ? 1189 PHE A HB3    1 c 
ATOM   2738 H HD1    . PHE A 1 181 ? 32.025  -9.974  12.891  1    16.517 ? 1189 PHE A HD1    1 c 
ATOM   2739 H HD2    . PHE A 1 181 ? 27.816  -10.56  13.235  1    15.863 ? 1189 PHE A HD2    1 c 
ATOM   2740 H HE1    . PHE A 1 181 ? 31.804  -9.778  10.444  1    17.804 ? 1189 PHE A HE1    1 c 
ATOM   2741 H HE2    . PHE A 1 181 ? 27.591  -10.364 10.791  1    16.313 ? 1189 PHE A HE2    1 c 
ATOM   2742 H HZ     . PHE A 1 181 ? 29.583  -9.973  9.387   1    16.984 ? 1189 PHE A HZ     1 c 
ATOM   2743 N N      . MET A 1 182 ? 30.577  -12.028 17.46   1    15.737 ? 1190 MET A N      1 ? 
ATOM   2744 C CA     . MET A 1 182 ? 30.644  -11.777 18.894  1    15.165 ? 1190 MET A CA     1 ? 
ATOM   2745 C C      . MET A 1 182 ? 31.673  -12.632 19.632  1    13.177 ? 1190 MET A C      1 ? 
ATOM   2746 O O      . MET A 1 182 ? 32.369  -12.117 20.512  1    15.603 ? 1190 MET A O      1 ? 
ATOM   2747 C CB     . MET A 1 182 ? 29.256  -11.897 19.536  1    14.128 ? 1190 MET A CB     1 ? 
ATOM   2748 C CG     . MET A 1 182 ? 29.229  -11.533 21.012  1    14.319 ? 1190 MET A CG     1 ? 
ATOM   2749 S SD     . MET A 1 182 ? 27.614  -11.819 21.793  1    13.462 ? 1190 MET A SD     1 ? 
ATOM   2750 C CE     . MET A 1 182 ? 26.705  -10.455 21.041  1    14.02  ? 1190 MET A CE     1 ? 
ATOM   2751 H H      . MET A 1 182 ? 29.99   -12.802 17.096  1    15.282 ? 1190 MET A H      1 ? 
ATOM   2752 H HA     . MET A 1 182 ? 30.97   -10.742 19.012  1    14.722 ? 1190 MET A HA     1 c 
ATOM   2753 H HB2    . MET A 1 182 ? 28.565  -11.246 18.998  1    14.389 ? 1190 MET A HB2    1 c 
ATOM   2754 H HB3    . MET A 1 182 ? 28.905  -12.925 19.419  1    14.389 ? 1190 MET A HB3    1 c 
ATOM   2755 H HG2    . MET A 1 182 ? 29.98   -12.121 21.543  1    14.118 ? 1190 MET A HG2    1 c 
ATOM   2756 H HG3    . MET A 1 182 ? 29.49   -10.478 21.126  1    14.116 ? 1190 MET A HG3    1 c 
ATOM   2757 H HE1    . MET A 1 182 ? 27.179  -9.509  21.313  1    13.894 ? 1190 MET A HE1    1 c 
ATOM   2758 H HE2    . MET A 1 182 ? 26.713  -10.568 19.955  1    13.909 ? 1190 MET A HE2    1 c 
ATOM   2759 H HE3    . MET A 1 182 ? 25.674  -10.463 21.402  1    13.899 ? 1190 MET A HE3    1 c 
ATOM   2760 N N      . GLU A 1 183 ? 31.76   -13.919 19.304  1    14.212 ? 1191 GLU A N      1 ? 
ATOM   2761 C CA     . GLU A 1 183 ? 32.475  -14.89  20.115  1    15.357 ? 1191 GLU A CA     1 ? 
ATOM   2762 C C      . GLU A 1 183 ? 33.899  -15.096 19.605  1    16.013 ? 1191 GLU A C      1 ? 
ATOM   2763 O O      . GLU A 1 183 ? 34.165  -15.046 18.403  1    16.168 ? 1191 GLU A O      1 ? 
ATOM   2764 C CB     . GLU A 1 183 ? 31.742  -16.228 20.07   1    13.343 ? 1191 GLU A CB     1 ? 
ATOM   2765 C CG     . GLU A 1 183 ? 30.363  -16.172 20.714  1    14.516 ? 1191 GLU A CG     1 ? 
ATOM   2766 C CD     . GLU A 1 183 ? 29.617  -17.489 20.639  1    13.855 ? 1191 GLU A CD     1 ? 
ATOM   2767 O OE1    . GLU A 1 183 ? 29.881  -18.28  19.71   1    14.843 ? 1191 GLU A OE1    1 ? 
ATOM   2768 O OE2    . GLU A 1 183 ? 28.726  -17.704 21.501  1    13.806 ? 1191 GLU A OE2    1 ? 
ATOM   2769 H H      . GLU A 1 183 ? 31.263  -14.258 18.46   1    14.153 ? 1191 GLU A H      1 ? 
ATOM   2770 H HA     . GLU A 1 183 ? 32.512  -14.529 21.144  1    14.877 ? 1191 GLU A HA     1 c 
ATOM   2771 H HB2    . GLU A 1 183 ? 31.639  -16.538 19.028  1    14.018 ? 1191 GLU A HB2    1 c 
ATOM   2772 H HB3    . GLU A 1 183 ? 32.347  -16.979 20.583  1    14.014 ? 1191 GLU A HB3    1 c 
ATOM   2773 H HG2    . GLU A 1 183 ? 30.469  -15.889 21.764  1    14.107 ? 1191 GLU A HG2    1 c 
ATOM   2774 H HG3    . GLU A 1 183 ? 29.767  -15.403 20.219  1    14.107 ? 1191 GLU A HG3    1 c 
ATOM   2775 N N      . ASP A 1 184 ? 34.827  -15.356 20.53   1    16.629 ? 1192 ASP A N      1 ? 
ATOM   2776 C CA     . ASP A 1 184 ? 36.21   -15.621 20.142  1    16.713 ? 1192 ASP A CA     1 ? 
ATOM   2777 C C      . ASP A 1 184 ? 36.359  -17.098 19.793  1    16.462 ? 1192 ASP A C      1 ? 
ATOM   2778 O O      . ASP A 1 184 ? 36.673  -17.93  20.644  1    18.113 ? 1192 ASP A O      1 ? 
ATOM   2779 C CB     . ASP A 1 184 ? 37.159  -15.186 21.249  1    16.775 ? 1192 ASP A CB     1 ? 
ATOM   2780 C CG     . ASP A 1 184 ? 38.615  -15.313 20.858  1    18.068 ? 1192 ASP A CG     1 ? 
ATOM   2781 O OD1    . ASP A 1 184 ? 38.893  -15.54  19.669  1    18.019 ? 1192 ASP A OD1    1 ? 
ATOM   2782 O OD2    . ASP A 1 184 ? 39.461  -15.183 21.767  1    20.826 ? 1192 ASP A OD2    1 ? 
ATOM   2783 H H      . ASP A 1 184 ? 34.555  -15.283 21.522  1    16.072 ? 1192 ASP A H      1 ? 
ATOM   2784 H HA     . ASP A 1 184 ? 36.438  -15.028 19.254  1    16.668 ? 1192 ASP A HA     1 c 
ATOM   2785 H HB2    . ASP A 1 184 ? 36.957  -14.144 21.506  1    17.046 ? 1192 ASP A HB2    1 c 
ATOM   2786 H HB3    . ASP A 1 184 ? 36.982  -15.797 22.137  1    17.075 ? 1192 ASP A HB3    1 c 
ATOM   2787 N N      . VAL A 1 185 ? 36.156  -17.419 18.517  1    14.68  ? 1193 VAL A N      1 ? 
ATOM   2788 C CA     . VAL A 1 185 ? 36.234  -18.789 18.02   1    15.28  ? 1193 VAL A CA     1 ? 
ATOM   2789 C C      . VAL A 1 185 ? 37.456  -18.859 17.107  1    17.45  ? 1193 VAL A C      1 ? 
ATOM   2790 O O      . VAL A 1 185 ? 37.377  -18.483 15.928  1    15.986 ? 1193 VAL A O      1 ? 
ATOM   2791 C CB     . VAL A 1 185 ? 34.96   -19.218 17.284  1    14.433 ? 1193 VAL A CB     1 ? 
ATOM   2792 C CG1    . VAL A 1 185 ? 35.057  -20.656 16.837  1    14.201 ? 1193 VAL A CG1    1 ? 
ATOM   2793 C CG2    . VAL A 1 185 ? 33.738  -19.02  18.18   1    15.509 ? 1193 VAL A CG2    1 ? 
ATOM   2794 H H      . VAL A 1 185 ? 35.944  -16.649 17.866  1    15.033 ? 1193 VAL A H      1 ? 
ATOM   2795 H HA     . VAL A 1 185 ? 36.386  -19.46  18.866  1    15.488 ? 1193 VAL A HA     1 c 
ATOM   2796 H HB     . VAL A 1 185 ? 34.856  -18.581 16.402  1    14.733 ? 1193 VAL A HB     1 c 
ATOM   2797 H HG11   . VAL A 1 185 ? 35.863  -20.761 16.108  1    14.286 ? 1193 VAL A HG11   1 c 
ATOM   2798 H HG12   . VAL A 1 185 ? 35.262  -21.294 17.699  1    14.274 ? 1193 VAL A HG12   1 c 
ATOM   2799 H HG13   . VAL A 1 185 ? 34.113  -20.96  16.378  1    14.287 ? 1193 VAL A HG13   1 c 
ATOM   2800 H HG21   . VAL A 1 185 ? 32.841  -19.355 17.654  1    15.203 ? 1193 VAL A HG21   1 c 
ATOM   2801 H HG22   . VAL A 1 185 ? 33.859  -19.601 19.096  1    15.203 ? 1193 VAL A HG22   1 c 
ATOM   2802 H HG23   . VAL A 1 185 ? 33.637  -17.962 18.433  1    15.202 ? 1193 VAL A HG23   1 c 
ATOM   2803 N N      . PRO A 1 186 ? 38.606  -19.339 17.607  1    19.774 ? 1194 PRO A N      1 ? 
ATOM   2804 C CA     . PRO A 1 186 ? 39.834  -19.19  16.834  1    23.029 ? 1194 PRO A CA     1 ? 
ATOM   2805 C C      . PRO A 1 186 ? 39.834  -19.92  15.501  1    20.619 ? 1194 PRO A C      1 ? 
ATOM   2806 O O      . PRO A 1 186 ? 40.539  -19.499 14.573  1    21.438 ? 1194 PRO A O      1 ? 
ATOM   2807 C CB     . PRO A 1 186 ? 40.922  -19.738 17.764  1    26.412 ? 1194 PRO A CB     1 ? 
ATOM   2808 C CG     . PRO A 1 186 ? 40.342  -19.534 19.116  1    25.801 ? 1194 PRO A CG     1 ? 
ATOM   2809 C CD     . PRO A 1 186 ? 38.887  -19.859 18.957  1    23.917 ? 1194 PRO A CD     1 ? 
ATOM   2810 H HA     . PRO A 1 186 ? 40.018  -18.132 16.659  1    22.476 ? 1194 PRO A HA     1 c 
ATOM   2811 H HB2    . PRO A 1 186 ? 41.106  -20.797 17.57   1    25.569 ? 1194 PRO A HB2    1 c 
ATOM   2812 H HB3    . PRO A 1 186 ? 41.854  -19.182 17.647  1    25.53  ? 1194 PRO A HB3    1 c 
ATOM   2813 H HG2    . PRO A 1 186 ? 40.809  -20.2   19.846  1    25.509 ? 1194 PRO A HG2    1 c 
ATOM   2814 H HG3    . PRO A 1 186 ? 40.473  -18.501 19.446  1    25.509 ? 1194 PRO A HG3    1 c 
ATOM   2815 H HD2    . PRO A 1 186 ? 38.707  -20.935 19.006  1    23.269 ? 1194 PRO A HD2    1 c 
ATOM   2816 H HD3    . PRO A 1 186 ? 38.281  -19.353 19.707  1    23.129 ? 1194 PRO A HD3    1 c 
ATOM   2817 N N      . ASN A 1 187 ? 39.084  -21.006 15.386  1    20.838 ? 1195 ASN A N      1 ? 
ATOM   2818 C CA     . ASN A 1 187 ? 39.091  -21.788 14.169  1    23.701 ? 1195 ASN A CA     1 ? 
ATOM   2819 C C      . ASN A 1 187 ? 38.036  -21.317 13.158  1    21.335 ? 1195 ASN A C      1 ? 
ATOM   2820 O O      . ASN A 1 187 ? 37.919  -21.933 12.099  1    22.776 ? 1195 ASN A O      1 ? 
ATOM   2821 C CB     . ASN A 1 187 ? 38.85   -23.259 14.493  1    24.519 ? 1195 ASN A CB     1 ? 
ATOM   2822 C CG     . ASN A 1 187 ? 37.62   -23.446 15.349  1    24.583 ? 1195 ASN A CG     1 ? 
ATOM   2823 O OD1    . ASN A 1 187 ? 37.602  -23.067 16.529  1    30.829 ? 1195 ASN A OD1    1 ? 
ATOM   2824 N ND2    . ASN A 1 187 ? 36.6    -24.072 14.785  1    22.093 ? 1195 ASN A ND2    1 ? 
ATOM   2825 H H      . ASN A 1 187 ? 38.519  -21.349 16.179  1    20.478 ? 1195 ASN A H      1 ? 
ATOM   2826 H HA     . ASN A 1 187 ? 40.078  -21.707 13.71   1    22.836 ? 1195 ASN A HA     1 c 
ATOM   2827 H HB2    . ASN A 1 187 ? 38.731  -23.818 13.564  1    24.461 ? 1195 ASN A HB2    1 c 
ATOM   2828 H HB3    . ASN A 1 187 ? 39.718  -23.659 15.02   1    24.503 ? 1195 ASN A HB3    1 c 
ATOM   2829 H HD21   . ASN A 1 187 ? 35.757  -24.171 15.328  1    21.555 ? 1195 ASN A HD21   1 ? 
ATOM   2830 H HD22   . ASN A 1 187 ? 36.668  -24.497 13.875  1    22.613 ? 1195 ASN A HD22   1 ? 
ATOM   2831 N N      . TYR A 1 188 ? 37.256  -20.267 13.462  1    18.062 ? 1196 TYR A N      1 ? 
ATOM   2832 C CA     . TYR A 1 188 ? 36.313  -19.679 12.503  1    15.717 ? 1196 TYR A CA     1 ? 
ATOM   2833 C C      . TYR A 1 188 ? 36.377  -18.156 12.6    1    16.516 ? 1196 TYR A C      1 ? 
ATOM   2834 O O      . TYR A 1 188 ? 35.708  -17.543 13.436  1    17.864 ? 1196 TYR A O      1 ? 
ATOM   2835 C CB     . TYR A 1 188 ? 34.886  -20.185 12.712  1    15.222 ? 1196 TYR A CB     1 ? 
ATOM   2836 C CG     . TYR A 1 188 ? 33.93   -19.673 11.644  1    15.335 ? 1196 TYR A CG     1 ? 
ATOM   2837 C CD1    . TYR A 1 188 ? 34.062  -20.058 10.307  1    13.982 ? 1196 TYR A CD1    1 ? 
ATOM   2838 C CD2    . TYR A 1 188 ? 32.899  -18.804 11.976  1    15.373 ? 1196 TYR A CD2    1 ? 
ATOM   2839 C CE1    . TYR A 1 188 ? 33.187  -19.581 9.334   1    14.33  ? 1196 TYR A CE1    1 ? 
ATOM   2840 C CE2    . TYR A 1 188 ? 32.031  -18.317 11.002  1    14.644 ? 1196 TYR A CE2    1 ? 
ATOM   2841 C CZ     . TYR A 1 188 ? 32.162  -18.725 9.684   1    15.322 ? 1196 TYR A CZ     1 ? 
ATOM   2842 O OH     . TYR A 1 188 ? 31.272  -18.234 8.751   1    15.065 ? 1196 TYR A OH     1 ? 
ATOM   2843 H H      . TYR A 1 188 ? 37.266  -19.869 14.411  1    17.797 ? 1196 TYR A H      1 ? 
ATOM   2844 H HA     . TYR A 1 188 ? 36.629  -19.967 11.499  1    16.228 ? 1196 TYR A HA     1 c 
ATOM   2845 H HB2    . TYR A 1 188 ? 34.893  -21.277 12.693  1    15.356 ? 1196 TYR A HB2    1 c 
ATOM   2846 H HB3    . TYR A 1 188 ? 34.536  -19.858 13.693  1    15.366 ? 1196 TYR A HB3    1 c 
ATOM   2847 H HD1    . TYR A 1 188 ? 34.857  -20.739 10.021  1    14.361 ? 1196 TYR A HD1    1 c 
ATOM   2848 H HD2    . TYR A 1 188 ? 32.779  -18.484 13.006  1    15.19  ? 1196 TYR A HD2    1 c 
ATOM   2849 H HE1    . TYR A 1 188 ? 33.298  -19.897 8.302   1    14.478 ? 1196 TYR A HE1    1 c 
ATOM   2850 H HE2    . TYR A 1 188 ? 31.225  -17.647 11.281  1    14.943 ? 1196 TYR A HE2    1 c 
ATOM   2851 H HH     . TYR A 1 188 ? 31.291  -18.675 7.882   1    16.766 ? 1196 TYR A HH     1 ? 
ATOM   2852 N N      . ARG A 1 189 ? 37.181  -17.563 11.735  1    16.214 ? 1197 ARG A N      1 ? 
ATOM   2853 C CA     . ARG A 1 189 ? 37.376  -16.121 11.67   1    17.638 ? 1197 ARG A CA     1 ? 
ATOM   2854 C C      . ARG A 1 189 ? 36.669  -15.63  10.413  1    16.948 ? 1197 ARG A C      1 ? 
ATOM   2855 O O      . ARG A 1 189 ? 37.184  -15.776 9.304   1    16.861 ? 1197 ARG A O      1 ? 
ATOM   2856 C CB     . ARG A 1 189 ? 38.867  -15.793 11.636  1    19.669 ? 1197 ARG A CB     1 ? 
ATOM   2857 C CG     . ARG A 1 189 ? 39.645  -16.226 12.869  1    19.951 ? 1197 ARG A CG     1 ? 
ATOM   2858 C CD     . ARG A 1 189 ? 39.051  -15.705 14.165  1    19.585 ? 1197 ARG A CD     1 ? 
ATOM   2859 N NE     . ARG A 1 189 ? 40.018  -15.829 15.264  1    20.333 ? 1197 ARG A NE     1 ? 
ATOM   2860 C CZ     . ARG A 1 189 ? 39.739  -15.637 16.539  1    21.576 ? 1197 ARG A CZ     1 ? 
ATOM   2861 N NH1    . ARG A 1 189 ? 38.506  -15.335 16.94   1    21.357 ? 1197 ARG A NH1    1 ? 
ATOM   2862 N NH2    . ARG A 1 189 ? 40.71   -15.752 17.443  1    22.422 ? 1197 ARG A NH2    1 ? 
ATOM   2863 H H      . ARG A 1 189 ? 37.624  -18.127 10.991  1    17.5   ? 1197 ARG A H      1 ? 
ATOM   2864 H HA     . ARG A 1 189 ? 36.915  -15.662 12.545  1    17.598 ? 1197 ARG A HA     1 c 
ATOM   2865 H HB2    . ARG A 1 189 ? 39.308  -16.273 10.76   1    19.337 ? 1197 ARG A HB2    1 c 
ATOM   2866 H HB3    . ARG A 1 189 ? 38.982  -14.714 11.513  1    19.281 ? 1197 ARG A HB3    1 c 
ATOM   2867 H HG2    . ARG A 1 189 ? 39.674  -17.317 12.908  1    19.809 ? 1197 ARG A HG2    1 c 
ATOM   2868 H HG3    . ARG A 1 189 ? 40.674  -15.871 12.785  1    19.809 ? 1197 ARG A HG3    1 c 
ATOM   2869 H HD2    . ARG A 1 189 ? 38.77   -14.657 14.045  1    19.829 ? 1197 ARG A HD2    1 c 
ATOM   2870 H HD3    . ARG A 1 189 ? 38.151  -16.273 14.409  1    19.825 ? 1197 ARG A HD3    1 c 
ATOM   2871 H HE     . ARG A 1 189 ? 40.92   -16.199 15.061  1    20.718 ? 1197 ARG A HE     1 ? 
ATOM   2872 H HH11   . ARG A 1 189 ? 37.697  -15.338 16.319  1    19.26  ? 1197 ARG A HH11   1 ? 
ATOM   2873 H HH12   . ARG A 1 189 ? 38.329  -15.12  17.915  1    19.558 ? 1197 ARG A HH12   1 ? 
ATOM   2874 H HH21   . ARG A 1 189 ? 41.614  -16.051 17.115  1    23.437 ? 1197 ARG A HH21   1 ? 
ATOM   2875 H HH22   . ARG A 1 189 ? 40.584  -15.566 18.422  1    23.522 ? 1197 ARG A HH22   1 ? 
ATOM   2876 N N      . PHE A 1 190 ? 35.486  -15.065 10.591  1    17.266 ? 1198 PHE A N      1 ? 
ATOM   2877 C CA     . PHE A 1 190 ? 34.658  -14.668 9.459   1    15.687 ? 1198 PHE A CA     1 ? 
ATOM   2878 C C      . PHE A 1 190 ? 35.119  -13.33  8.898   1    17.052 ? 1198 PHE A C      1 ? 
ATOM   2879 O O      . PHE A 1 190 ? 35.214  -12.339 9.627   1    15.74  ? 1198 PHE A O      1 ? 
ATOM   2880 C CB     . PHE A 1 190 ? 33.2    -14.554 9.899   1    16.424 ? 1198 PHE A CB     1 ? 
ATOM   2881 C CG     . PHE A 1 190 ? 32.279  -14.183 8.773   1    17.273 ? 1198 PHE A CG     1 ? 
ATOM   2882 C CD1    . PHE A 1 190 ? 32.053  -15.071 7.722   1    15.89  ? 1198 PHE A CD1    1 ? 
ATOM   2883 C CD2    . PHE A 1 190 ? 31.659  -12.94  8.739   1    16.153 ? 1198 PHE A CD2    1 ? 
ATOM   2884 C CE1    . PHE A 1 190 ? 31.22   -14.735 6.67    1    15.939 ? 1198 PHE A CE1    1 ? 
ATOM   2885 C CE2    . PHE A 1 190 ? 30.811  -12.599 7.68    1    15.852 ? 1198 PHE A CE2    1 ? 
ATOM   2886 C CZ     . PHE A 1 190 ? 30.598  -13.498 6.654   1    16.294 ? 1198 PHE A CZ     1 ? 
ATOM   2887 H H      . PHE A 1 190 ? 35.164  -14.919 11.564  1    16.046 ? 1198 PHE A H      1 ? 
ATOM   2888 H HA     . PHE A 1 190 ? 34.735  -15.429 8.682   1    16.352 ? 1198 PHE A HA     1 c 
ATOM   2889 H HB2    . PHE A 1 190 ? 32.884  -15.512 10.318  1    16.443 ? 1198 PHE A HB2    1 c 
ATOM   2890 H HB3    . PHE A 1 190 ? 33.129  -13.798 10.683  1    16.443 ? 1198 PHE A HB3    1 c 
ATOM   2891 H HD1    . PHE A 1 190 ? 32.538  -16.041 7.732   1    16.191 ? 1198 PHE A HD1    1 c 
ATOM   2892 H HD2    . PHE A 1 190 ? 31.826  -12.234 9.546   1    16.319 ? 1198 PHE A HD2    1 c 
ATOM   2893 H HE1    . PHE A 1 190 ? 31.049  -15.442 5.865   1    16.013 ? 1198 PHE A HE1    1 c 
ATOM   2894 H HE2    . PHE A 1 190 ? 30.325  -11.629 7.665   1    16.021 ? 1198 PHE A HE2    1 c 
ATOM   2895 H HZ     . PHE A 1 190 ? 29.942  -13.235 5.832   1    16.109 ? 1198 PHE A HZ     1 c 
ATOM   2896 N N      . GLY A 1 191 ? 35.377  -13.301 7.591   1    16.537 ? 1199 GLY A N      1 ? 
ATOM   2897 C CA     . GLY A 1 191 ? 35.81   -12.086 6.917   1    17.391 ? 1199 GLY A CA     1 ? 
ATOM   2898 C C      . GLY A 1 191 ? 35.012  -11.799 5.655   1    17.899 ? 1199 GLY A C      1 ? 
ATOM   2899 O O      . GLY A 1 191 ? 35.468  -11.046 4.801   1    17.264 ? 1199 GLY A O      1 ? 
ATOM   2900 H H      . GLY A 1 191 ? 35.401  -14.203 7.084   1    15.478 ? 1199 GLY A H      1 ? 
ATOM   2901 H HA2    . GLY A 1 191 ? 35.718  -11.242 7.604   1    17.29  ? 1199 GLY A HA2    1 c 
ATOM   2902 H HA3    . GLY A 1 191 ? 36.865  -12.193 6.657   1    17.311 ? 1199 GLY A HA3    1 c 
ATOM   2903 N N      . GLY A 1 192 ? 33.831  -12.403 5.525   1    16.068 ? 1200 GLY A N      1 ? 
ATOM   2904 C CA     . GLY A 1 192 ? 32.957  -12.176 4.39    1    15.603 ? 1200 GLY A CA     1 ? 
ATOM   2905 C C      . GLY A 1 192 ? 31.937  -11.088 4.663   1    16.343 ? 1200 GLY A C      1 ? 
ATOM   2906 O O      . GLY A 1 192 ? 32.182  -10.14  5.407   1    17.726 ? 1200 GLY A O      1 ? 
ATOM   2907 H H      . GLY A 1 192 ? 33.483  -12.983 6.304   1    16.631 ? 1200 GLY A H      1 ? 
ATOM   2908 H HA2    . GLY A 1 192 ? 33.564  -11.891 3.529   1    15.879 ? 1200 GLY A HA2    1 c 
ATOM   2909 H HA3    . GLY A 1 192 ? 32.445  -13.103 4.139   1    15.89  ? 1200 GLY A HA3    1 c 
ATOM   2910 N N      . LEU A 1 193 ? 30.776  -11.23  4.026   1    15.187 ? 1201 LEU A N      1 ? 
ATOM   2911 C CA     . LEU A 1 193 ? 29.655  -10.327 4.224   1    15.088 ? 1201 LEU A CA     1 ? 
ATOM   2912 C C      . LEU A 1 193 ? 28.475  -11.129 4.746   1    14.221 ? 1201 LEU A C      1 ? 
ATOM   2913 O O      . LEU A 1 193 ? 28.072  -12.121 4.127   1    12.008 ? 1201 LEU A O      1 ? 
ATOM   2914 C CB     . LEU A 1 193 ? 29.266  -9.634  2.917   1    16.659 ? 1201 LEU A CB     1 ? 
ATOM   2915 C CG     . LEU A 1 193 ? 27.961  -8.831  2.955   1    18.559 ? 1201 LEU A CG     1 ? 
ATOM   2916 C CD1    . LEU A 1 193 ? 28.067  -7.671  3.93    1    19.393 ? 1201 LEU A CD1    1 ? 
ATOM   2917 C CD2    . LEU A 1 193 ? 27.519  -8.384  1.596   1    17.482 ? 1201 LEU A CD2    1 ? 
ATOM   2918 H H      . LEU A 1 193 ? 30.669  -11.99  3.33    1    15.503 ? 1201 LEU A H      1 ? 
ATOM   2919 H HA     . LEU A 1 193 ? 29.933  -9.576  4.965   1    15.229 ? 1201 LEU A HA     1 c 
ATOM   2920 H HB2    . LEU A 1 193 ? 30.077  -8.961  2.633   1    16.689 ? 1201 LEU A HB2    1 c 
ATOM   2921 H HB3    . LEU A 1 193 ? 29.179  -10.396 2.14    1    16.689 ? 1201 LEU A HB3    1 c 
ATOM   2922 H HG     . LEU A 1 193 ? 27.18   -9.492  3.335   1    18.123 ? 1201 LEU A HG     1 c 
ATOM   2923 H HD11   . LEU A 1 193 ? 28.191  -8.057  4.944   1    19.146 ? 1201 LEU A HD11   1 c 
ATOM   2924 H HD12   . LEU A 1 193 ? 28.927  -7.053  3.672   1    19.147 ? 1201 LEU A HD12   1 c 
ATOM   2925 H HD13   . LEU A 1 193 ? 27.158  -7.068  3.881   1    19.11  ? 1201 LEU A HD13   1 c 
ATOM   2926 H HD21   . LEU A 1 193 ? 26.6    -7.801  1.684   1    17.808 ? 1201 LEU A HD21   1 c 
ATOM   2927 H HD22   . LEU A 1 193 ? 28.298  -7.767  1.144   1    17.924 ? 1201 LEU A HD22   1 c 
ATOM   2928 H HD23   . LEU A 1 193 ? 27.337  -9.256  0.966   1    17.783 ? 1201 LEU A HD23   1 c 
ATOM   2929 N N      . ALA A 1 194 ? 27.945  -10.709 5.892   1    14.323 ? 1202 ALA A N      1 ? 
ATOM   2930 C CA     . ALA A 1 194 ? 26.7    -11.222 6.438   1    13.236 ? 1202 ALA A CA     1 ? 
ATOM   2931 C C      . ALA A 1 194 ? 25.663  -10.112 6.331   1    14.015 ? 1202 ALA A C      1 ? 
ATOM   2932 O O      . ALA A 1 194 ? 25.916  -8.984  6.756   1    14.623 ? 1202 ALA A O      1 ? 
ATOM   2933 C CB     . ALA A 1 194 ? 26.897  -11.644 7.893   1    14.123 ? 1202 ALA A CB     1 ? 
ATOM   2934 H H      . ALA A 1 194 ? 28.389  -9.911  6.37    1    14.581 ? 1202 ALA A H      1 ? 
ATOM   2935 H HA     . ALA A 1 194 ? 26.373  -12.075 5.843   1    13.729 ? 1202 ALA A HA     1 c 
ATOM   2936 H HB1    . ALA A 1 194 ? 25.956  -12.028 8.294   1    13.875 ? 1202 ALA A HB1    1 c 
ATOM   2937 H HB2    . ALA A 1 194 ? 27.658  -12.425 7.949   1    13.875 ? 1202 ALA A HB2    1 c 
ATOM   2938 H HB3    . ALA A 1 194 ? 27.217  -10.785 8.485   1    13.884 ? 1202 ALA A HB3    1 c 
ATOM   2939 N N      . TRP A 1 195 ? 24.51   -10.422 5.743   1    12.917 ? 1203 TRP A N      1 ? 
ATOM   2940 C CA     . TRP A 1 195 ? 23.495  -9.418  5.464   1    13.277 ? 1203 TRP A CA     1 ? 
ATOM   2941 C C      . TRP A 1 195 ? 22.16   -9.939  5.978   1    12.821 ? 1203 TRP A C      1 ? 
ATOM   2942 O O      . TRP A 1 195 ? 21.594  -10.874 5.405   1    12.152 ? 1203 TRP A O      1 ? 
ATOM   2943 C CB     . TRP A 1 195 ? 23.428  -9.139  3.96    1    13.405 ? 1203 TRP A CB     1 ? 
ATOM   2944 C CG     . TRP A 1 195 ? 22.681  -7.895  3.584   1    14.856 ? 1203 TRP A CG     1 ? 
ATOM   2945 C CD1    . TRP A 1 195 ? 21.789  -7.183  4.34    1    16.349 ? 1203 TRP A CD1    1 ? 
ATOM   2946 C CD2    . TRP A 1 195 ? 22.772  -7.223  2.328   1    17.239 ? 1203 TRP A CD2    1 ? 
ATOM   2947 N NE1    . TRP A 1 195 ? 21.335  -6.096  3.628   1    18.751 ? 1203 TRP A NE1    1 ? 
ATOM   2948 C CE2    . TRP A 1 195 ? 21.92   -6.106  2.387   1    16.676 ? 1203 TRP A CE2    1 ? 
ATOM   2949 C CE3    . TRP A 1 195 ? 23.497  -7.459  1.157   1    18.044 ? 1203 TRP A CE3    1 ? 
ATOM   2950 C CZ2    . TRP A 1 195 ? 21.771  -5.225  1.313   1    17.108 ? 1203 TRP A CZ2    1 ? 
ATOM   2951 C CZ3    . TRP A 1 195 ? 23.363  -6.58   0.092   1    18.216 ? 1203 TRP A CZ3    1 ? 
ATOM   2952 C CH2    . TRP A 1 195 ? 22.495  -5.484  0.173   1    18.176 ? 1203 TRP A CH2    1 ? 
ATOM   2953 H H      . TRP A 1 195 ? 24.335  -11.393 5.43    1    13.356 ? 1203 TRP A H      1 ? 
ATOM   2954 H HA     . TRP A 1 195 ? 23.748  -8.495  5.986   1    13.196 ? 1203 TRP A HA     1 c 
ATOM   2955 H HB2    . TRP A 1 195 ? 24.448  -9.065  3.578   1    13.684 ? 1203 TRP A HB2    1 c 
ATOM   2956 H HB3    . TRP A 1 195 ? 22.957  -9.994  3.47    1    13.677 ? 1203 TRP A HB3    1 c 
ATOM   2957 H HD1    . TRP A 1 195 ? 21.492  -7.414  5.357   1    16.456 ? 1203 TRP A HD1    1 c 
ATOM   2958 H HE1    . TRP A 1 195 ? 20.665  -5.413  3.962   1    17.69  ? 1203 TRP A HE1    1 ? 
ATOM   2959 H HE3    . TRP A 1 195 ? 24.164  -8.311  1.088   1    17.883 ? 1203 TRP A HE3    1 c 
ATOM   2960 H HZ2    . TRP A 1 195 ? 21.109  -4.369  1.379   1    17.278 ? 1203 TRP A HZ2    1 c 
ATOM   2961 H HZ3    . TRP A 1 195 ? 23.915  -6.76   -0.825  1    18.144 ? 1203 TRP A HZ3    1 c 
ATOM   2962 H HH2    . TRP A 1 195 ? 22.404  -4.813  -0.676  1    17.928 ? 1203 TRP A HH2    1 c 
ATOM   2963 N N      . LEU A 1 196 ? 21.658  -9.335  7.054   1    14.661 ? 1204 LEU A N      1 ? 
ATOM   2964 C CA     . LEU A 1 196 ? 20.407  -9.748  7.67    1    14.399 ? 1204 LEU A CA     1 ? 
ATOM   2965 C C      . LEU A 1 196 ? 19.265  -8.845  7.204   1    13.846 ? 1204 LEU A C      1 ? 
ATOM   2966 O O      . LEU A 1 196 ? 19.35   -7.618  7.316   1    15.277 ? 1204 LEU A O      1 ? 
ATOM   2967 C CB     . LEU A 1 196 ? 20.519  -9.702  9.196   1    14.016 ? 1204 LEU A CB     1 ? 
ATOM   2968 C CG     . LEU A 1 196 ? 19.245  -9.993  9.981   1    16.845 ? 1204 LEU A CG     1 ? 
ATOM   2969 C CD1    . LEU A 1 196 ? 18.76   -11.412 9.74    1    16.301 ? 1204 LEU A CD1    1 ? 
ATOM   2970 C CD2    . LEU A 1 196 ? 19.453  -9.741  11.463  1    16.772 ? 1204 LEU A CD2    1 ? 
ATOM   2971 H H      . LEU A 1 196 ? 22.189  -8.551  7.472   1    13.895 ? 1204 LEU A H      1 ? 
ATOM   2972 H HA     . LEU A 1 196 ? 20.191  -10.771 7.36    1    14.268 ? 1204 LEU A HA     1 c 
ATOM   2973 H HB2    . LEU A 1 196 ? 21.281  -10.422 9.501   1    14.679 ? 1204 LEU A HB2    1 c 
ATOM   2974 H HB3    . LEU A 1 196 ? 20.877  -8.71   9.479   1    14.679 ? 1204 LEU A HB3    1 c 
ATOM   2975 H HG     . LEU A 1 196 ? 18.468  -9.31   9.634   1    16.174 ? 1204 LEU A HG     1 c 
ATOM   2976 H HD11   . LEU A 1 196 ? 18.545  -11.549 8.678   1    16.416 ? 1204 LEU A HD11   1 c 
ATOM   2977 H HD12   . LEU A 1 196 ? 19.532  -12.119 10.05   1    16.433 ? 1204 LEU A HD12   1 c 
ATOM   2978 H HD13   . LEU A 1 196 ? 17.851  -11.59  10.32   1    16.398 ? 1204 LEU A HD13   1 c 
ATOM   2979 H HD21   . LEU A 1 196 ? 20.25   -10.387 11.835  1    16.779 ? 1204 LEU A HD21   1 c 
ATOM   2980 H HD22   . LEU A 1 196 ? 19.73   -8.696  11.62   1    16.779 ? 1204 LEU A HD22   1 c 
ATOM   2981 H HD23   . LEU A 1 196 ? 18.529  -9.956  12.003  1    16.738 ? 1204 LEU A HD23   1 c 
ATOM   2982 N N      . PHE A 1 197 ? 18.195  -9.465  6.705   1    14.026 ? 1205 PHE A N      1 ? 
ATOM   2983 C CA     . PHE A 1 197 ? 16.925  -8.808  6.417   1    15.769 ? 1205 PHE A CA     1 ? 
ATOM   2984 C C      . PHE A 1 197 ? 15.892  -9.383  7.375   1    14.123 ? 1205 PHE A C      1 ? 
ATOM   2985 O O      . PHE A 1 197 ? 15.764  -10.608 7.483   1    14.91  ? 1205 PHE A O      1 ? 
ATOM   2986 C CB     . PHE A 1 197 ? 16.474  -9.139  4.993   1    16.656 ? 1205 PHE A CB     1 ? 
ATOM   2987 C CG     . PHE A 1 197 ? 17.267  -8.449  3.909   1    15.241 ? 1205 PHE A CG     1 ? 
ATOM   2988 C CD1    . PHE A 1 197 ? 18.489  -8.947  3.493   1    15.099 ? 1205 PHE A CD1    1 ? 
ATOM   2989 C CD2    . PHE A 1 197 ? 16.752  -7.318  3.281   1    17.492 ? 1205 PHE A CD2    1 ? 
ATOM   2990 C CE1    . PHE A 1 197 ? 19.205  -8.32   2.479   1    16.245 ? 1205 PHE A CE1    1 ? 
ATOM   2991 C CE2    . PHE A 1 197 ? 17.471  -6.684  2.276   1    17.289 ? 1205 PHE A CE2    1 ? 
ATOM   2992 C CZ     . PHE A 1 197 ? 18.688  -7.187  1.87    1    16.25  ? 1205 PHE A CZ     1 ? 
ATOM   2993 H H      . PHE A 1 197 ? 18.201  -10.497 6.648   1    13.61  ? 1205 PHE A H      1 ? 
ATOM   2994 H HA     . PHE A 1 197 ? 17.014  -7.731  6.549   1    15.275 ? 1205 PHE A HA     1 c 
ATOM   2995 H HB2    . PHE A 1 197 ? 16.548  -10.219 4.849   1    16.14  ? 1205 PHE A HB2    1 c 
ATOM   2996 H HB3    . PHE A 1 197 ? 15.423  -8.862  4.89    1    16.14  ? 1205 PHE A HB3    1 c 
ATOM   2997 H HD1    . PHE A 1 197 ? 18.892  -9.836  3.966   1    15.41  ? 1205 PHE A HD1    1 c 
ATOM   2998 H HD2    . PHE A 1 197 ? 15.793  -6.919  3.594   1    16.911 ? 1205 PHE A HD2    1 c 
ATOM   2999 H HE1    . PHE A 1 197 ? 20.167  -8.715  2.169   1    16.001 ? 1205 PHE A HE1    1 c 
ATOM   3000 H HE2    . PHE A 1 197 ? 17.065  -5.798  1.799   1    17.069 ? 1205 PHE A HE2    1 c 
ATOM   3001 H HZ     . PHE A 1 197 ? 19.247  -6.69   1.084   1    16.465 ? 1205 PHE A HZ     1 c 
ATOM   3002 N N      . LEU A 1 198 ? 15.147  -8.518  8.061   1    16.456 ? 1206 LEU A N      1 ? 
ATOM   3003 C CA     . LEU A 1 198 ? 14.176  -8.962  9.056   1    16.909 ? 1206 LEU A CA     1 ? 
ATOM   3004 C C      . LEU A 1 198 ? 12.847  -8.257  8.818   1    17.432 ? 1206 LEU A C      1 ? 
ATOM   3005 O O      . LEU A 1 198 ? 12.79   -7.027  8.838   1    17.481 ? 1206 LEU A O      1 ? 
ATOM   3006 C CB     . LEU A 1 198 ? 14.667  -8.668  10.472  1    17.69  ? 1206 LEU A CB     1 ? 
ATOM   3007 C CG     . LEU A 1 198 ? 13.685  -9.034  11.595  1    18.211 ? 1206 LEU A CG     1 ? 
ATOM   3008 C CD1    . LEU A 1 198 ? 13.358  -10.513 11.616  1    19.077 ? 1206 LEU A CD1    1 ? 
ATOM   3009 C CD2    . LEU A 1 198 ? 14.208  -8.536  12.957  1    19.575 ? 1206 LEU A CD2    1 ? 
ATOM   3010 H H      . LEU A 1 198 ? 15.251  -7.499  7.888   1    15.451 ? 1206 LEU A H      1 ? 
ATOM   3011 H HA     . LEU A 1 198 ? 14.029  -10.037 8.944   1    17.022 ? 1206 LEU A HA     1 c 
ATOM   3012 H HB2    . LEU A 1 198 ? 15.597  -9.219  10.633  1    17.626 ? 1206 LEU A HB2    1 c 
ATOM   3013 H HB3    . LEU A 1 198 ? 14.891  -7.602  10.542  1    17.626 ? 1206 LEU A HB3    1 c 
ATOM   3014 H HG     . LEU A 1 198 ? 12.751  -8.503  11.403  1    18.504 ? 1206 LEU A HG     1 c 
ATOM   3015 H HD11   . LEU A 1 198 ? 12.892  -10.798 10.67   1    18.816 ? 1206 LEU A HD11   1 c 
ATOM   3016 H HD12   . LEU A 1 198 ? 14.275  -11.089 11.757  1    18.824 ? 1206 LEU A HD12   1 c 
ATOM   3017 H HD13   . LEU A 1 198 ? 12.668  -10.723 12.437  1    18.808 ? 1206 LEU A HD13   1 c 
ATOM   3018 H HD21   . LEU A 1 198 ? 15.184  -8.981  13.158  1    19.19  ? 1206 LEU A HD21   1 c 
ATOM   3019 H HD22   . LEU A 1 198 ? 14.301  -7.449  12.935  1    19.212 ? 1206 LEU A HD22   1 c 
ATOM   3020 H HD23   . LEU A 1 198 ? 13.508  -8.825  13.744  1    19.169 ? 1206 LEU A HD23   1 c 
ATOM   3021 N N      . GLY A 1 199 ? 11.78   -9.033  8.646   1    18.651 ? 1207 GLY A N      1 ? 
ATOM   3022 C CA     . GLY A 1 199 ? 10.427  -8.507  8.564   1    18.468 ? 1207 GLY A CA     1 ? 
ATOM   3023 C C      . GLY A 1 199 ? 9.636   -8.849  9.822   1    19.769 ? 1207 GLY A C      1 ? 
ATOM   3024 O O      . GLY A 1 199 ? 9.579   -10.002 10.233  1    18.209 ? 1207 GLY A O      1 ? 
ATOM   3025 H H      . GLY A 1 199 ? 11.918  -10.057 8.57    1    18.267 ? 1207 GLY A H      1 ? 
ATOM   3026 H HA2    . GLY A 1 199 ? 10.465  -7.426  8.433   1    18.803 ? 1207 GLY A HA2    1 c 
ATOM   3027 H HA3    . GLY A 1 199 ? 9.932   -8.938  7.693   1    18.797 ? 1207 GLY A HA3    1 c 
ATOM   3028 N N      . VAL A 1 200 ? 9.044   -7.816  10.425  1    19.606 ? 1208 VAL A N      1 ? 
ATOM   3029 C CA     . VAL A 1 200 ? 8.174   -7.945  11.586  1    22.634 ? 1208 VAL A CA     1 ? 
ATOM   3030 C C      . VAL A 1 200 ? 7.022   -6.949  11.426  1    22.683 ? 1208 VAL A C      1 ? 
ATOM   3031 O O      . VAL A 1 200 ? 6.992   -6.158  10.483  1    25.765 ? 1208 VAL A O      1 ? 
ATOM   3032 C CB     . VAL A 1 200 ? 8.915   -7.729  12.923  1    19.406 ? 1208 VAL A CB     1 ? 
ATOM   3033 C CG1    . VAL A 1 200 ? 9.983   -8.791  13.139  1    19.417 ? 1208 VAL A CG1    1 ? 
ATOM   3034 C CG2    . VAL A 1 200 ? 9.508   -6.33   12.985  1    17.71  ? 1208 VAL A CG2    1 ? 
ATOM   3035 H H      . VAL A 1 200 ? 9.254   -6.858  10.098  1    19.804 ? 1208 VAL A H      1 ? 
ATOM   3036 H HA     . VAL A 1 200 ? 7.757   -8.954  11.586  1    21.448 ? 1208 VAL A HA     1 c 
ATOM   3037 H HB     . VAL A 1 200 ? 8.179   -7.82   13.722  1    19.712 ? 1208 VAL A HB     1 c 
ATOM   3038 H HG11   . VAL A 1 200 ? 9.525   -9.782  13.109  1    19.427 ? 1208 VAL A HG11   1 c 
ATOM   3039 H HG12   . VAL A 1 200 ? 10.738  -8.717  12.353  1    19.428 ? 1208 VAL A HG12   1 c 
ATOM   3040 H HG13   . VAL A 1 200 ? 10.457  -8.639  14.111  1    19.467 ? 1208 VAL A HG13   1 c 
ATOM   3041 H HG21   . VAL A 1 200 ? 10.15   -6.165  12.117  1    18.197 ? 1208 VAL A HG21   1 c 
ATOM   3042 H HG22   . VAL A 1 200 ? 8.704   -5.591  12.988  1    18.206 ? 1208 VAL A HG22   1 c 
ATOM   3043 H HG23   . VAL A 1 200 ? 10.098  -6.225  13.898  1    18.245 ? 1208 VAL A HG23   1 c 
ATOM   3044 N N      . ALA A 1 201 ? 6.075   -6.973  12.363  1    24.385 ? 1209 ALA A N      1 ? 
ATOM   3045 C CA     . ALA A 1 201 ? 4.855   -6.191  12.215  1    26.182 ? 1209 ALA A CA     1 ? 
ATOM   3046 C C      . ALA A 1 201 ? 5.095   -4.697  12.436  1    24.877 ? 1209 ALA A C      1 ? 
ATOM   3047 O O      . ALA A 1 201 ? 4.511   -3.857  11.741  1    27.546 ? 1209 ALA A O      1 ? 
ATOM   3048 C CB     . ALA A 1 201 ? 3.764   -6.705  13.151  1    27.309 ? 1209 ALA A CB     1 ? 
ATOM   3049 H H      . ALA A 1 201 ? 6.128   -7.693  13.104  1    25.553 ? 1209 ALA A H      1 ? 
ATOM   3050 H HA     . ALA A 1 201 ? 4.51    -6.317  11.189  1    25.759 ? 1209 ALA A HA     1 c 
ATOM   3051 H HB1    . ALA A 1 201 ? 2.859   -6.106  13.024  1    26.973 ? 1209 ALA A HB1    1 c 
ATOM   3052 H HB2    . ALA A 1 201 ? 3.541   -7.748  12.917  1    26.973 ? 1209 ALA A HB2    1 c 
ATOM   3053 H HB3    . ALA A 1 201 ? 4.103   -6.632  14.186  1    26.914 ? 1209 ALA A HB3    1 c 
ATOM   3054 N N      . ASN A 1 202 ? 5.916   -4.348  13.425  1    23.359 ? 1210 ASN A N      1 ? 
ATOM   3055 C CA     . ASN A 1 202 ? 6.165   -2.956  13.773  1    25.656 ? 1210 ASN A CA     1 ? 
ATOM   3056 C C      . ASN A 1 202 ? 7.442   -2.894  14.606  1    23.33  ? 1210 ASN A C      1 ? 
ATOM   3057 O O      . ASN A 1 202 ? 8.039   -3.92   14.933  1    24.359 ? 1210 ASN A O      1 ? 
ATOM   3058 C CB     . ASN A 1 202 ? 4.959   -2.313  14.474  1    25.04  ? 1210 ASN A CB     1 ? 
ATOM   3059 C CG     . ASN A 1 202 ? 4.499   -3.078  15.699  1    25.513 ? 1210 ASN A CG     1 ? 
ATOM   3060 O OD1    . ASN A 1 202 ? 5.293   -3.733  16.383  1    32.208 ? 1210 ASN A OD1    1 ? 
ATOM   3061 N ND2    . ASN A 1 202 ? 3.212   -2.991  16.006  1    23.062 ? 1210 ASN A ND2    1 ? 
ATOM   3062 H H      . ASN A 1 202 ? 6.4     -5.079  13.974  1    25.437 ? 1210 ASN A H      1 ? 
ATOM   3063 H HA     . ASN A 1 202 ? 6.334   -2.403  12.849  1    24.627 ? 1210 ASN A HA     1 c 
ATOM   3064 H HB2    . ASN A 1 202 ? 5.229   -1.303  14.778  1    25.207 ? 1210 ASN A HB2    1 c 
ATOM   3065 H HB3    . ASN A 1 202 ? 4.13    -2.242  13.767  1    25.24  ? 1210 ASN A HB3    1 c 
ATOM   3066 H HD21   . ASN A 1 202 ? 2.779   -3.658  16.623  1    23.709 ? 1210 ASN A HD21   1 ? 
ATOM   3067 H HD22   . ASN A 1 202 ? 2.654   -2.289  15.55   1    23.328 ? 1210 ASN A HD22   1 ? 
ATOM   3068 N N      . SER A 1 203 ? 7.81    -1.673  14.962  1    22.025 ? 1211 SER A N      1 ? 
ATOM   3069 C CA     . SER A 1 203 ? 9.018   -1.38   15.702  1    24.046 ? 1211 SER A CA     1 ? 
ATOM   3070 C C      . SER A 1 203 ? 9.064   -2.175  17.017  1    25.668 ? 1211 SER A C      1 ? 
ATOM   3071 O O      . SER A 1 203 ? 10.129  -2.689  17.402  1    23.594 ? 1211 SER A O      1 ? 
ATOM   3072 C CB     . SER A 1 203 ? 9.104   0.09    15.951  1    26.257 ? 1211 SER A CB     1 ? 
ATOM   3073 O OG     . SER A 1 203 ? 10.404  0.44    16.404  1    29.969 ? 1211 SER A OG     1 ? 
ATOM   3074 H H      . SER A 1 203 ? 7.207   -0.889  14.673  1    25.174 ? 1211 SER A H      1 ? 
ATOM   3075 H HA     . SER A 1 203 ? 9.872   -1.679  15.091  1    24.306 ? 1211 SER A HA     1 c 
ATOM   3076 H HB2    . SER A 1 203 ? 8.886   0.628   15.029  1    26.495 ? 1211 SER A HB2    1 c 
ATOM   3077 H HB3    . SER A 1 203 ? 8.365   0.377   16.702  1    26.518 ? 1211 SER A HB3    1 c 
ATOM   3078 H HG     . SER A 1 203 ? 10.643  -0.113  17.164  1    29.009 ? 1211 SER A HG     1 ? 
ATOM   3079 N N      . ASP A 1 204 ? 7.914   -2.229  17.714  1    22.495 ? 1212 ASP A N      1 ? 
ATOM   3080 C CA     . ASP A 1 204 ? 7.783   -2.942  18.977  1    22.659 ? 1212 ASP A CA     1 ? 
ATOM   3081 C C      . ASP A 1 204 ? 7.887   -4.455  18.816  1    21.688 ? 1212 ASP A C      1 ? 
ATOM   3082 O O      . ASP A 1 204 ? 8.076   -5.156  19.818  1    23.441 ? 1212 ASP A O      1 ? 
ATOM   3083 C CB     . ASP A 1 204 ? 6.465   -2.59   19.665  1    24.458 ? 1212 ASP A CB     1 ? 
ATOM   3084 C CG     . ASP A 1 204 ? 6.561   -1.347  20.544  1    25.252 ? 1212 ASP A CG     1 ? 
ATOM   3085 O OD1    . ASP A 1 204 ? 7.577   -0.637  20.486  1    23.312 ? 1212 ASP A OD1    1 ? 
ATOM   3086 O OD2    . ASP A 1 204 ? 5.593   -1.083  21.287  1    26.417 ? 1212 ASP A OD2    1 ? 
ATOM   3087 H H      . ASP A 1 204 ? 7.084   -1.718  17.368  1    23.378 ? 1212 ASP A H      1 ? 
ATOM   3088 H HA     . ASP A 1 204 ? 8.594   -2.617  19.632  1    22.764 ? 1212 ASP A HA     1 c 
ATOM   3089 H HB2    . ASP A 1 204 ? 5.699   -2.419  18.905  1    24.221 ? 1212 ASP A HB2    1 c 
ATOM   3090 H HB3    . ASP A 1 204 ? 6.148   -3.429  20.287  1    24.208 ? 1212 ASP A HB3    1 c 
ATOM   3091 N N      . SER A 1 205 ? 7.777   -4.971  17.589  1    21.151 ? 1213 SER A N      1 ? 
ATOM   3092 C CA     . SER A 1 205 ? 7.88    -6.4    17.33   1    20.496 ? 1213 SER A CA     1 ? 
ATOM   3093 C C      . SER A 1 205 ? 9.281   -6.83   16.913  1    17.541 ? 1213 SER A C      1 ? 
ATOM   3094 O O      . SER A 1 205 ? 9.499   -8.007  16.625  1    18.249 ? 1213 SER A O      1 ? 
ATOM   3095 C CB     . SER A 1 205 ? 6.884   -6.812  16.246  1    22.16  ? 1213 SER A CB     1 ? 
ATOM   3096 O OG     . SER A 1 205 ? 5.557   -6.439  16.594  1    20.41  ? 1213 SER A OG     1 ? 
ATOM   3097 H H      . SER A 1 205 ? 7.623   -4.342  16.789  1    23.722 ? 1213 SER A H      1 ? 
ATOM   3098 H HA     . SER A 1 205 ? 7.623   -6.931  18.248  1    20.349 ? 1213 SER A HA     1 c 
ATOM   3099 H HB2    . SER A 1 205 ? 7.16    -6.339  15.303  1    21.462 ? 1213 SER A HB2    1 c 
ATOM   3100 H HB3    . SER A 1 205 ? 6.929   -7.891  16.112  1    21.546 ? 1213 SER A HB3    1 c 
ATOM   3101 H HG     . SER A 1 205 ? 5.07    -7.085  17.138  1    23.363 ? 1213 SER A HG     1 ? 
ATOM   3102 N N      . LEU A 1 206 ? 10.23   -5.9    16.855  1    19.199 ? 1214 LEU A N      1 ? 
ATOM   3103 C CA     . LEU A 1 206 ? 11.599  -6.262  16.524  1    19.305 ? 1214 LEU A CA     1 ? 
ATOM   3104 C C      . LEU A 1 206 ? 12.178  -7.189  17.59   1    19.268 ? 1214 LEU A C      1 ? 
ATOM   3105 O O      . LEU A 1 206 ? 11.784  -7.165  18.763  1    19.247 ? 1214 LEU A O      1 ? 
ATOM   3106 C CB     . LEU A 1 206 ? 12.454  -5.014  16.369  1    20.662 ? 1214 LEU A CB     1 ? 
ATOM   3107 C CG     . LEU A 1 206 ? 12.252  -4.239  15.067  1    21.907 ? 1214 LEU A CG     1 ? 
ATOM   3108 C CD1    . LEU A 1 206 ? 12.869  -2.824  15.221  1    22.837 ? 1214 LEU A CD1    1 ? 
ATOM   3109 C CD2    . LEU A 1 206 ? 12.824  -5.012  13.891  1    23.071 ? 1214 LEU A CD2    1 ? 
ATOM   3110 H H      . LEU A 1 206 ? 10.02   -4.928  17.157  1    19.758 ? 1214 LEU A H      1 ? 
ATOM   3111 H HA     . LEU A 1 206 ? 11.584  -6.802  15.575  1    19.551 ? 1214 LEU A HA     1 c 
ATOM   3112 H HB2    . LEU A 1 206 ? 12.239  -4.346  17.206  1    20.613 ? 1214 LEU A HB2    1 c 
ATOM   3113 H HB3    . LEU A 1 206 ? 13.503  -5.309  16.436  1    20.599 ? 1214 LEU A HB3    1 c 
ATOM   3114 H HG     . LEU A 1 206 ? 11.179  -4.123  14.904  1    22.043 ? 1214 LEU A HG     1 c 
ATOM   3115 H HD11   . LEU A 1 206 ? 13.937  -2.911  15.43   1    22.58  ? 1214 LEU A HD11   1 c 
ATOM   3116 H HD12   . LEU A 1 206 ? 12.725  -2.26   14.297  1    22.625 ? 1214 LEU A HD12   1 c 
ATOM   3117 H HD13   . LEU A 1 206 ? 12.379  -2.3    16.045  1    22.537 ? 1214 LEU A HD13   1 c 
ATOM   3118 H HD21   . LEU A 1 206 ? 12.272  -5.945  13.762  1    22.688 ? 1214 LEU A HD21   1 c 
ATOM   3119 H HD22   . LEU A 1 206 ? 12.739  -4.412  12.983  1    22.685 ? 1214 LEU A HD22   1 c 
ATOM   3120 H HD23   . LEU A 1 206 ? 13.876  -5.236  14.079  1    22.663 ? 1214 LEU A HD23   1 c 
ATOM   3121 N N      . LEU A 1 207 ? 13.12   -8.026  17.154  1    18.423 ? 1215 LEU A N      1 ? 
ATOM   3122 C CA     . LEU A 1 207 ? 13.7    -9.078  17.983  1    16.959 ? 1215 LEU A CA     1 ? 
ATOM   3123 C C      . LEU A 1 207 ? 15.217  -8.927  17.927  1    17.383 ? 1215 LEU A C      1 ? 
ATOM   3124 O O      . LEU A 1 207 ? 15.81   -9.025  16.845  1    18.008 ? 1215 LEU A O      1 ? 
ATOM   3125 C CB     . LEU A 1 207 ? 13.284  -10.458 17.47   1    16.958 ? 1215 LEU A CB     1 ? 
ATOM   3126 C CG     . LEU A 1 207 ? 11.777  -10.709 17.31   1    18.54  ? 1215 LEU A CG     1 ? 
ATOM   3127 C CD1    . LEU A 1 207 ? 11.518  -12.04  16.605  1    18.329 ? 1215 LEU A CD1    1 ? 
ATOM   3128 C CD2    . LEU A 1 207 ? 11.031  -10.63  18.631  1    20.821 ? 1215 LEU A CD2    1 ? 
ATOM   3129 H H      . LEU A 1 207 ? 13.473  -7.942  16.184  1    17.837 ? 1215 LEU A H      1 ? 
ATOM   3130 H HA     . LEU A 1 207 ? 13.361  -8.949  19.012  1    17.304 ? 1215 LEU A HA     1 c 
ATOM   3131 H HB2    . LEU A 1 207 ? 13.762  -10.617 16.501  1    17.291 ? 1215 LEU A HB2    1 c 
ATOM   3132 H HB3    . LEU A 1 207 ? 13.684  -11.208 18.155  1    17.291 ? 1215 LEU A HB3    1 c 
ATOM   3133 H HG     . LEU A 1 207 ? 11.378  -9.921  16.667  1    18.597 ? 1215 LEU A HG     1 c 
ATOM   3134 H HD11   . LEU A 1 207 ? 11.984  -12.027 15.618  1    18.378 ? 1215 LEU A HD11   1 c 
ATOM   3135 H HD12   . LEU A 1 207 ? 11.942  -12.855 17.196  1    18.382 ? 1215 LEU A HD12   1 c 
ATOM   3136 H HD13   . LEU A 1 207 ? 10.442  -12.193 16.496  1    18.372 ? 1215 LEU A HD13   1 c 
ATOM   3137 H HD21   . LEU A 1 207 ? 11.166  -9.639  19.068  1    20.13  ? 1215 LEU A HD21   1 c 
ATOM   3138 H HD22   . LEU A 1 207 ? 9.967   -10.809 18.461  1    20.134 ? 1215 LEU A HD22   1 c 
ATOM   3139 H HD23   . LEU A 1 207 ? 11.421  -11.385 19.316  1    20.062 ? 1215 LEU A HD23   1 c 
ATOM   3140 N N      . TYR A 1 208 ? 15.837  -8.667  19.084  1    16.698 ? 1216 TYR A N      1 ? 
ATOM   3141 C CA     . TYR A 1 208 ? 17.29   -8.57   19.197  1    15.362 ? 1216 TYR A CA     1 ? 
ATOM   3142 C C      . TYR A 1 208 ? 17.868  -7.384  18.411  1    16.561 ? 1216 TYR A C      1 ? 
ATOM   3143 O O      . TYR A 1 208 ? 19.026  -7.413  17.987  1    14.394 ? 1216 TYR A O      1 ? 
ATOM   3144 C CB     . TYR A 1 208 ? 17.995  -9.87   18.769  1    15.632 ? 1216 TYR A CB     1 ? 
ATOM   3145 C CG     . TYR A 1 208 ? 17.342  -11.146 19.281  1    13.295 ? 1216 TYR A CG     1 ? 
ATOM   3146 C CD1    . TYR A 1 208 ? 17.401  -11.5   20.634  1    13.655 ? 1216 TYR A CD1    1 ? 
ATOM   3147 C CD2    . TYR A 1 208 ? 16.674  -12     18.412  1    14.273 ? 1216 TYR A CD2    1 ? 
ATOM   3148 C CE1    . TYR A 1 208 ? 16.818  -12.665 21.103  1    13.423 ? 1216 TYR A CE1    1 ? 
ATOM   3149 C CE2    . TYR A 1 208 ? 16.083  -13.172 18.868  1    14.753 ? 1216 TYR A CE2    1 ? 
ATOM   3150 C CZ     . TYR A 1 208 ? 16.171  -13.508 20.209  1    13.548 ? 1216 TYR A CZ     1 ? 
ATOM   3151 O OH     . TYR A 1 208 ? 15.59   -14.674 20.625  1    13.735 ? 1216 TYR A OH     1 ? 
ATOM   3152 H H      . TYR A 1 208 ? 15.271  -8.503  19.936  1    16.341 ? 1216 TYR A H      1 ? 
ATOM   3153 H HA     . TYR A 1 208 ? 17.521  -8.406  20.252  1    15.866 ? 1216 TYR A HA     1 c 
ATOM   3154 H HB2    . TYR A 1 208 ? 18.025  -9.903  17.679  1    15.055 ? 1216 TYR A HB2    1 c 
ATOM   3155 H HB3    . TYR A 1 208 ? 19.026  -9.836  19.127  1    15.034 ? 1216 TYR A HB3    1 c 
ATOM   3156 H HD1    . TYR A 1 208 ? 17.919  -10.851 21.331  1    13.547 ? 1216 TYR A HD1    1 c 
ATOM   3157 H HD2    . TYR A 1 208 ? 16.616  -11.751 17.358  1    14.155 ? 1216 TYR A HD2    1 c 
ATOM   3158 H HE1    . TYR A 1 208 ? 16.884  -12.928 22.153  1    13.541 ? 1216 TYR A HE1    1 c 
ATOM   3159 H HE2    . TYR A 1 208 ? 15.576  -13.834 18.174  1    14.36  ? 1216 TYR A HE2    1 c 
ATOM   3160 H HH     . TYR A 1 208 ? 15.773  -14.793 21.535  1    14.749 ? 1216 TYR A HH     1 ? 
ATOM   3161 N N      . ASP A 1 209 ? 17.077  -6.32   18.222  1    17.324 ? 1217 ASP A N      1 ? 
ATOM   3162 C CA     . ASP A 1 209 ? 17.49   -5.223  17.359  1    18.097 ? 1217 ASP A CA     1 ? 
ATOM   3163 C C      . ASP A 1 209 ? 18.771  -4.548  17.854  1    19.935 ? 1217 ASP A C      1 ? 
ATOM   3164 O O      . ASP A 1 209 ? 19.63   -4.167  17.049  1    19.509 ? 1217 ASP A O      1 ? 
ATOM   3165 C CB     . ASP A 1 209 ? 16.368  -4.205  17.241  1    18.692 ? 1217 ASP A CB     1 ? 
ATOM   3166 C CG     . ASP A 1 209 ? 16.693  -3.063  16.287  1    18.992 ? 1217 ASP A CG     1 ? 
ATOM   3167 O OD1    . ASP A 1 209 ? 16.99   -3.319  15.106  1    18.614 ? 1217 ASP A OD1    1 ? 
ATOM   3168 O OD2    . ASP A 1 209 ? 16.639  -1.906  16.729  1    20.591 ? 1217 ASP A OD2    1 ? 
ATOM   3169 H H      . ASP A 1 209 ? 16.134  -6.306  18.633  1    17.615 ? 1217 ASP A H      1 ? 
ATOM   3170 H HA     . ASP A 1 209 ? 17.678  -5.627  16.362  1    18.39  ? 1217 ASP A HA     1 c 
ATOM   3171 H HB2    . ASP A 1 209 ? 15.466  -4.707  16.887  1    18.641 ? 1217 ASP A HB2    1 c 
ATOM   3172 H HB3    . ASP A 1 209 ? 16.16   -3.785  18.228  1    18.628 ? 1217 ASP A HB3    1 c 
ATOM   3173 N N      . GLU A 1 210 ? 18.912  -4.376  19.171  1    21.261 ? 1218 GLU A N      1 ? 
ATOM   3174 C CA     . GLU A 1 210 ? 20.105  -3.72   19.682  1    23.032 ? 1218 GLU A CA     1 ? 
ATOM   3175 C C      . GLU A 1 210 ? 21.361  -4.526  19.38   1    19.797 ? 1218 GLU A C      1 ? 
ATOM   3176 O O      . GLU A 1 210 ? 22.41   -3.962  19.056  1    19.137 ? 1218 GLU A O      1 ? 
ATOM   3177 C CB     . GLU A 1 210 ? 19.97   -3.419  21.165  1    27.113 ? 1218 GLU A CB     1 ? 
ATOM   3178 C CG     . GLU A 1 210 ? 19.315  -2.046  21.388  1    37.85  ? 1218 GLU A CG     1 ? 
ATOM   3179 C CD     . GLU A 1 210 ? 19.247  -1.02   20.222  1    45.231 ? 1218 GLU A CD     1 ? 
ATOM   3180 O OE1    . GLU A 1 210 ? 20.267  -0.394  19.818  1    44.96  ? 1218 GLU A OE1    1 ? 
ATOM   3181 O OE2    . GLU A 1 210 ? 18.125  -0.846  19.669  1    47.734 ? 1218 GLU A OE2    1 ? 
ATOM   3182 H H      . GLU A 1 210 ? 18.181  -4.716  19.819  1    23.08  ? 1218 GLU A H      1 ? 
ATOM   3183 H HA     . GLU A 1 210 ? 20.203  -2.771  19.157  1    22.928 ? 1218 GLU A HA     1 c 
ATOM   3184 H HB2    . GLU A 1 210 ? 19.363  -4.194  21.635  1    28.127 ? 1218 GLU A HB2    1 c 
ATOM   3185 H HB3    . GLU A 1 210 ? 20.959  -3.439  21.627  1    28.06  ? 1218 GLU A HB3    1 c 
ATOM   3186 H HG2    . GLU A 1 210 ? 18.293  -2.216  21.731  1    36.547 ? 1218 GLU A HG2    1 c 
ATOM   3187 H HG3    . GLU A 1 210 ? 19.833  -1.56   22.218  1    36.547 ? 1218 GLU A HG3    1 c 
ATOM   3188 N N      . GLU A 1 211 ? 21.262  -5.854  19.469  1    17.732 ? 1219 GLU A N      1 ? 
ATOM   3189 C CA     . GLU A 1 211 ? 22.403  -6.715  19.159  1    17.228 ? 1219 GLU A CA     1 ? 
ATOM   3190 C C      . GLU A 1 211 ? 22.804  -6.563  17.692  1    16.626 ? 1219 GLU A C      1 ? 
ATOM   3191 O O      . GLU A 1 211 ? 23.987  -6.387  17.373  1    17.902 ? 1219 GLU A O      1 ? 
ATOM   3192 C CB     . GLU A 1 211 ? 22.052  -8.161  19.486  1    16.319 ? 1219 GLU A CB     1 ? 
ATOM   3193 C CG     . GLU A 1 211 ? 23.169  -9.151  19.211  1    18.307 ? 1219 GLU A CG     1 ? 
ATOM   3194 C CD     . GLU A 1 211 ? 23.052  -10.387 20.096  1    17.048 ? 1219 GLU A CD     1 ? 
ATOM   3195 O OE1    . GLU A 1 211 ? 22.979  -10.204 21.329  1    14.517 ? 1219 GLU A OE1    1 ? 
ATOM   3196 O OE2    . GLU A 1 211 ? 23.047  -11.526 19.582  1    16.322 ? 1219 GLU A OE2    1 ? 
ATOM   3197 H H      . GLU A 1 211 ? 20.346  -6.271  19.703  1    18.147 ? 1219 GLU A H      1 ? 
ATOM   3198 H HA     . GLU A 1 211 ? 23.244  -6.407  19.784  1    17.048 ? 1219 GLU A HA     1 c 
ATOM   3199 H HB2    . GLU A 1 211 ? 21.773  -8.222  20.539  1    16.914 ? 1219 GLU A HB2    1 c 
ATOM   3200 H HB3    . GLU A 1 211 ? 21.181  -8.45   18.895  1    16.916 ? 1219 GLU A HB3    1 c 
ATOM   3201 H HG2    . GLU A 1 211 ? 23.133  -9.46   18.164  1    17.579 ? 1219 GLU A HG2    1 c 
ATOM   3202 H HG3    . GLU A 1 211 ? 24.134  -8.673  19.395  1    17.579 ? 1219 GLU A HG3    1 c 
ATOM   3203 N N      . PHE A 1 212 ? 21.827  -6.622  16.787  1    17.105 ? 1220 PHE A N      1 ? 
ATOM   3204 C CA     . PHE A 1 212 ? 22.146  -6.515  15.37   1    18.073 ? 1220 PHE A CA     1 ? 
ATOM   3205 C C      . PHE A 1 212 ? 22.676  -5.121  15.03   1    17.344 ? 1220 PHE A C      1 ? 
ATOM   3206 O O      . PHE A 1 212 ? 23.635  -4.986  14.257  1    18.563 ? 1220 PHE A O      1 ? 
ATOM   3207 C CB     . PHE A 1 212 ? 20.922  -6.88   14.526  1    16.922 ? 1220 PHE A CB     1 ? 
ATOM   3208 C CG     . PHE A 1 212 ? 20.406  -8.279  14.791  1    15.823 ? 1220 PHE A CG     1 ? 
ATOM   3209 C CD1    . PHE A 1 212 ? 21.282  -9.345  15.006  1    16.52  ? 1220 PHE A CD1    1 ? 
ATOM   3210 C CD2    . PHE A 1 212 ? 19.042  -8.53   14.844  1    14.664 ? 1220 PHE A CD2    1 ? 
ATOM   3211 C CE1    . PHE A 1 212 ? 20.802  -10.613 15.251  1    17.56  ? 1220 PHE A CE1    1 ? 
ATOM   3212 C CE2    . PHE A 1 212 ? 18.56   -9.809  15.095  1    17.032 ? 1220 PHE A CE2    1 ? 
ATOM   3213 C CZ     . PHE A 1 212 ? 19.445  -10.857 15.296  1    17.196 ? 1220 PHE A CZ     1 ? 
ATOM   3214 H H      . PHE A 1 212 ? 20.836  -6.712  17.081  1    17.426 ? 1220 PHE A H      1 ? 
ATOM   3215 H HA     . PHE A 1 212 ? 22.936  -7.235  15.15   1    17.537 ? 1220 PHE A HA     1 c 
ATOM   3216 H HB2    . PHE A 1 212 ? 20.127  -6.162  14.735  1    16.918 ? 1220 PHE A HB2    1 c 
ATOM   3217 H HB3    . PHE A 1 212 ? 21.188  -6.794  13.47   1    16.915 ? 1220 PHE A HB3    1 c 
ATOM   3218 H HD1    . PHE A 1 212 ? 22.353  -9.174  14.971  1    16.607 ? 1220 PHE A HD1    1 c 
ATOM   3219 H HD2    . PHE A 1 212 ? 18.344  -7.715  14.685  1    15.448 ? 1220 PHE A HD2    1 c 
ATOM   3220 H HE1    . PHE A 1 212 ? 21.5    -11.429 15.41   1    17.221 ? 1220 PHE A HE1    1 c 
ATOM   3221 H HE2    . PHE A 1 212 ? 17.49   -9.988  15.127  1    16.522 ? 1220 PHE A HE2    1 c 
ATOM   3222 H HZ     . PHE A 1 212 ? 19.074  -11.858 15.492  1    17.209 ? 1220 PHE A HZ     1 c 
ATOM   3223 N N      . THR A 1 213 ? 22.076  -4.073  15.603  1    16.622 ? 1221 THR A N      1 ? 
ATOM   3224 C CA     . THR A 1 213 ? 22.564  -2.734  15.33   1    18.419 ? 1221 THR A CA     1 ? 
ATOM   3225 C C      . THR A 1 213 ? 24.007  -2.568  15.809  1    19.087 ? 1221 THR A C      1 ? 
ATOM   3226 O O      . THR A 1 213 ? 24.802  -1.869  15.171  1    22.776 ? 1221 THR A O      1 ? 
ATOM   3227 C CB     . THR A 1 213 ? 21.622  -1.709  15.957  1    21.599 ? 1221 THR A CB     1 ? 
ATOM   3228 O OG1    . THR A 1 213 ? 20.335  -1.825  15.345  1    19.393 ? 1221 THR A OG1    1 ? 
ATOM   3229 C CG2    . THR A 1 213 ? 22.153  -0.298  15.82   1    22.366 ? 1221 THR A CG2    1 ? 
ATOM   3230 H H      . THR A 1 213 ? 21.274  -4.207  16.245  1    17.165 ? 1221 THR A H      1 ? 
ATOM   3231 H HA     . THR A 1 213 ? 22.547  -2.588  14.248  1    18.7   ? 1221 THR A HA     1 c 
ATOM   3232 H HB     . THR A 1 213 ? 21.526  -1.93   17.022  1    20.703 ? 1221 THR A HB     1 c 
ATOM   3233 H HG1    . THR A 1 213 ? 19.828  -2.592  15.627  1    23.366 ? 1221 THR A HG1    1 ? 
ATOM   3234 H HG21   . THR A 1 213 ? 22.371  -0.092  14.77   1    22.119 ? 1221 THR A HG21   1 c 
ATOM   3235 H HG22   . THR A 1 213 ? 21.404  0.41    16.181  1    22.118 ? 1221 THR A HG22   1 c 
ATOM   3236 H HG23   . THR A 1 213 ? 23.067  -0.19   16.408  1    22.022 ? 1221 THR A HG23   1 c 
ATOM   3237 N N      . SER A 1 214 ? 24.375  -3.177  16.927  1    18.614 ? 1222 SER A N      1 ? 
ATOM   3238 C CA     . SER A 1 214 ? 25.751  -3.062  17.388  1    21.175 ? 1222 SER A CA     1 ? 
ATOM   3239 C C      . SER A 1 214 ? 26.746  -3.691  16.416  1    20.696 ? 1222 SER A C      1 ? 
ATOM   3240 O O      . SER A 1 214 ? 27.877  -3.206  16.323  1    20.581 ? 1222 SER A O      1 ? 
ATOM   3241 C CB     . SER A 1 214 ? 25.982  -3.578  18.779  1    22.766 ? 1222 SER A CB     1 ? 
ATOM   3242 O OG     . SER A 1 214 ? 25.658  -4.964  18.841  1    28.029 ? 1222 SER A OG     1 ? 
ATOM   3243 H H      . SER A 1 214 ? 23.642  -3.586  17.535  1    19.652 ? 1222 SER A H      1 ? 
ATOM   3244 H HA     . SER A 1 214 ? 25.977  -1.994  17.412  1    20.861 ? 1222 SER A HA     1 c 
ATOM   3245 H HB2    . SER A 1 214 ? 27.028  -3.432  19.054  1    23.641 ? 1222 SER A HB2    1 c 
ATOM   3246 H HB3    . SER A 1 214 ? 25.358  -3.023  19.482  1    23.539 ? 1222 SER A HB3    1 c 
ATOM   3247 H HG     . SER A 1 214 ? 24.696  -5.015  18.873  1    27.382 ? 1222 SER A HG     1 ? 
ATOM   3248 N N      . TYR A 1 215 ? 26.351  -4.743  15.679  1    19.475 ? 1223 TYR A N      1 ? 
ATOM   3249 C CA     . TYR A 1 215 ? 27.26   -5.284  14.677  1    17.595 ? 1223 TYR A CA     1 ? 
ATOM   3250 C C      . TYR A 1 215 ? 27.535  -4.285  13.553  1    18.177 ? 1223 TYR A C      1 ? 
ATOM   3251 O O      . TYR A 1 215 ? 28.62   -4.315  12.961  1    18.505 ? 1223 TYR A O      1 ? 
ATOM   3252 C CB     . TYR A 1 215 ? 26.703  -6.568  14.067  1    17.406 ? 1223 TYR A CB     1 ? 
ATOM   3253 C CG     . TYR A 1 215 ? 26.526  -7.746  15.015  1    17.195 ? 1223 TYR A CG     1 ? 
ATOM   3254 C CD1    . TYR A 1 215 ? 27.453  -8.049  16.011  1    17.335 ? 1223 TYR A CD1    1 ? 
ATOM   3255 C CD2    . TYR A 1 215 ? 25.428  -8.575  14.872  1    17.504 ? 1223 TYR A CD2    1 ? 
ATOM   3256 C CE1    . TYR A 1 215 ? 27.275  -9.145  16.846  1    16.656 ? 1223 TYR A CE1    1 ? 
ATOM   3257 C CE2    . TYR A 1 215 ? 25.232  -9.675  15.687  1    17.636 ? 1223 TYR A CE2    1 ? 
ATOM   3258 C CZ     . TYR A 1 215 ? 26.161  -9.96   16.681  1    16.935 ? 1223 TYR A CZ     1 ? 
ATOM   3259 O OH     . TYR A 1 215 ? 25.985  -11.05  17.502  1    17.775 ? 1223 TYR A OH     1 ? 
ATOM   3260 H H      . TYR A 1 215 ? 25.399  -5.142  15.772  1    20.731 ? 1223 TYR A H      1 ? 
ATOM   3261 H HA     . TYR A 1 215 ? 28.207  -5.519  15.167  1    18.007 ? 1223 TYR A HA     1 c 
ATOM   3262 H HB2    . TYR A 1 215 ? 25.734  -6.336  13.621  1    17.382 ? 1223 TYR A HB2    1 c 
ATOM   3263 H HB3    . TYR A 1 215 ? 27.365  -6.873  13.255  1    17.397 ? 1223 TYR A HB3    1 c 
ATOM   3264 H HD1    . TYR A 1 215 ? 28.326  -7.418  16.139  1    17.166 ? 1223 TYR A HD1    1 c 
ATOM   3265 H HD2    . TYR A 1 215 ? 24.703  -8.36   14.094  1    17.458 ? 1223 TYR A HD2    1 c 
ATOM   3266 H HE1    . TYR A 1 215 ? 28.003  -9.367  17.62   1    16.879 ? 1223 TYR A HE1    1 c 
ATOM   3267 H HE2    . TYR A 1 215 ? 24.36   -10.307 15.556  1    17.459 ? 1223 TYR A HE2    1 c 
ATOM   3268 H HH     . TYR A 1 215 ? 25.157  -11.48  17.21   1    18.094 ? 1223 TYR A HH     1 ? 
ATOM   3269 N N      . LEU A 1 216 ? 26.581  -3.402  13.236  1    19.861 ? 1224 LEU A N      1 ? 
ATOM   3270 C CA     . LEU A 1 216 ? 26.844  -2.388  12.212  1    19.595 ? 1224 LEU A CA     1 ? 
ATOM   3271 C C      . LEU A 1 216 ? 27.99   -1.472  12.622  1    20.563 ? 1224 LEU A C      1 ? 
ATOM   3272 O O      . LEU A 1 216 ? 28.749  -1.004  11.768  1    19.114 ? 1224 LEU A O      1 ? 
ATOM   3273 C CB     . LEU A 1 216 ? 25.606  -1.535  11.962  1    18.108 ? 1224 LEU A CB     1 ? 
ATOM   3274 C CG     . LEU A 1 216 ? 24.439  -2.173  11.216  1    18.404 ? 1224 LEU A CG     1 ? 
ATOM   3275 C CD1    . LEU A 1 216 ? 23.221  -1.251  11.303  1    18.842 ? 1224 LEU A CD1    1 ? 
ATOM   3276 C CD2    . LEU A 1 216 ? 24.788  -2.504  9.782   1    19.879 ? 1224 LEU A CD2    1 ? 
ATOM   3277 H H      . LEU A 1 216 ? 25.664  -3.427  13.714  1    19.233 ? 1224 LEU A H      1 ? 
ATOM   3278 H HA     . LEU A 1 216 ? 27.12   -2.899  11.288  1    19.539 ? 1224 LEU A HA     1 c 
ATOM   3279 H HB2    . LEU A 1 216 ? 25.239  -1.182  12.927  1    18.523 ? 1224 LEU A HB2    1 c 
ATOM   3280 H HB3    . LEU A 1 216 ? 25.916  -0.646  11.409  1    18.53  ? 1224 LEU A HB3    1 c 
ATOM   3281 H HG     . LEU A 1 216 ? 24.186  -3.107  11.722  1    18.688 ? 1224 LEU A HG     1 c 
ATOM   3282 H HD11   . LEU A 1 216 ? 23.46   -0.287  10.851  1    18.716 ? 1224 LEU A HD11   1 c 
ATOM   3283 H HD12   . LEU A 1 216 ? 22.382  -1.704  10.77   1    18.716 ? 1224 LEU A HD12   1 c 
ATOM   3284 H HD13   . LEU A 1 216 ? 22.949  -1.104  12.35   1    18.702 ? 1224 LEU A HD13   1 c 
ATOM   3285 H HD21   . LEU A 1 216 ? 25.62   -3.212  9.763   1    19.447 ? 1224 LEU A HD21   1 c 
ATOM   3286 H HD22   . LEU A 1 216 ? 23.922  -2.949  9.289   1    19.446 ? 1224 LEU A HD22   1 c 
ATOM   3287 H HD23   . LEU A 1 216 ? 25.076  -1.592  9.256   1    19.417 ? 1224 LEU A HD23   1 c 
ATOM   3288 N N      . LYS A 1 217 ? 28.112  -1.206  13.92   1    20.989 ? 1225 LYS A N      1 ? 
ATOM   3289 C CA     . LYS A 1 217 ? 29.137  -0.305  14.415  1    23.142 ? 1225 LYS A CA     1 ? 
ATOM   3290 C C      . LYS A 1 217 ? 30.464  -1.016  14.636  1    25.201 ? 1225 LYS A C      1 ? 
ATOM   3291 O O      . LYS A 1 217 ? 31.524  -0.395  14.531  1    23.942 ? 1225 LYS A O      1 ? 
ATOM   3292 C CB     . LYS A 1 217 ? 28.66   0.327   15.72   1    27.723 ? 1225 LYS A CB     1 ? 
ATOM   3293 C CG     . LYS A 1 217 ? 27.387  1.106   15.432  1    33.828 ? 1225 LYS A CG     1 ? 
ATOM   3294 C CD     . LYS A 1 217 ? 26.684  1.834   16.57   1    41.342 ? 1225 LYS A CD     1 ? 
ATOM   3295 C CE     . LYS A 1 217 ? 25.275  2.117   16.131  1    47.759 ? 1225 LYS A CE     1 ? 
ATOM   3296 N NZ     . LYS A 1 217 ? 24.451  2.427   17.298  1    47.49  ? 1225 LYS A NZ     1 ? 
ATOM   3297 H H      . LYS A 1 217 ? 27.428  -1.621  14.579  1    21.172 ? 1225 LYS A H      1 ? 
ATOM   3298 H HA     . LYS A 1 217 ? 29.285  0.486   13.677  1    23.783 ? 1225 LYS A HA     1 c 
ATOM   3299 H HB2    . LYS A 1 217 ? 28.456  -0.447  16.463  1    27.849 ? 1225 LYS A HB2    1 c 
ATOM   3300 H HB3    . LYS A 1 217 ? 29.422  1.002   16.114  1    27.849 ? 1225 LYS A HB3    1 c 
ATOM   3301 H HG2    . LYS A 1 217 ? 27.621  1.841   14.659  1    33.839 ? 1225 LYS A HG2    1 c 
ATOM   3302 H HG3    . LYS A 1 217 ? 26.671  0.412   14.989  1    33.885 ? 1225 LYS A HG3    1 c 
ATOM   3303 H HD2    . LYS A 1 217 ? 26.672  1.209   17.465  1    40.865 ? 1225 LYS A HD2    1 c 
ATOM   3304 H HD3    . LYS A 1 217 ? 27.197  2.773   16.788  1    40.865 ? 1225 LYS A HD3    1 c 
ATOM   3305 H HE2    . LYS A 1 217 ? 25.261  2.964   15.442  1    46.203 ? 1225 LYS A HE2    1 c 
ATOM   3306 H HE3    . LYS A 1 217 ? 24.861  1.244   15.622  1    46.103 ? 1225 LYS A HE3    1 c 
ATOM   3307 H HZ1    . LYS A 1 217 ? 23.47   2.471   17.029  1    47.329 ? 1225 LYS A HZ1    1 ? 
ATOM   3308 H HZ2    . LYS A 1 217 ? 24.596  1.688   17.995  1    48.324 ? 1225 LYS A HZ2    1 ? 
ATOM   3309 H HZ3    . LYS A 1 217 ? 24.743  3.317   17.698  1    47.537 ? 1225 LYS A HZ3    1 ? 
ATOM   3310 N N      . GLN A 1 218 ? 30.413  -2.314  14.952  1    22.088 ? 1226 GLN A N      1 ? 
ATOM   3311 C CA     . GLN A 1 218 ? 31.613  -3.093  15.213  1    22.63  ? 1226 GLN A CA     1 ? 
ATOM   3312 C C      . GLN A 1 218 ? 32.232  -3.658  13.934  1    21.499 ? 1226 GLN A C      1 ? 
ATOM   3313 O O      . GLN A 1 218 ? 33.461  -3.743  13.83   1    21.343 ? 1226 GLN A O      1 ? 
ATOM   3314 C CB     . GLN A 1 218 ? 31.291  -4.254  16.146  1    28.506 ? 1226 GLN A CB     1 ? 
ATOM   3315 C CG     . GLN A 1 218 ? 30.849  -3.821  17.539  1    35.696 ? 1226 GLN A CG     1 ? 
ATOM   3316 C CD     . GLN A 1 218 ? 30.455  -5.025  18.366  1    38.112 ? 1226 GLN A CD     1 ? 
ATOM   3317 O OE1    . GLN A 1 218 ? 31.017  -6.115  18.199  1    35.037 ? 1226 GLN A OE1    1 ? 
ATOM   3318 N NE2    . GLN A 1 218 ? 29.48   -4.841  19.247  1    44.858 ? 1226 GLN A NE2    1 ? 
ATOM   3319 H H      . GLN A 1 218 ? 29.481  -2.77   15.009  1    22.509 ? 1226 GLN A H      1 ? 
ATOM   3320 H HA     . GLN A 1 218 ? 32.345  -2.444  15.699  1    23.264 ? 1226 GLN A HA     1 c 
ATOM   3321 H HB2    . GLN A 1 218 ? 30.5    -4.857  15.695  1    28.469 ? 1226 GLN A HB2    1 c 
ATOM   3322 H HB3    . GLN A 1 218 ? 32.178  -4.885  16.236  1    28.496 ? 1226 GLN A HB3    1 c 
ATOM   3323 H HG2    . GLN A 1 218 ? 31.665  -3.293  18.035  1    34.458 ? 1226 GLN A HG2    1 c 
ATOM   3324 H HG3    . GLN A 1 218 ? 30.001  -3.138  17.461  1    34.362 ? 1226 GLN A HG3    1 c 
ATOM   3325 H HE21   . GLN A 1 218 ? 29.074  -3.916  19.361  1    43.432 ? 1226 GLN A HE21   1 ? 
ATOM   3326 H HE22   . GLN A 1 218 ? 29.155  -5.616  19.815  1    42.897 ? 1226 GLN A HE22   1 ? 
ATOM   3327 N N      . TYR A 1 219 ? 31.39   -4.051  12.972  1    18.066 ? 1227 TYR A N      1 ? 
ATOM   3328 C CA     . TYR A 1 219 ? 31.839  -4.695  11.744  1    19.371 ? 1227 TYR A CA     1 ? 
ATOM   3329 C C      . TYR A 1 219 ? 31.194  -4.033  10.527  1    19.334 ? 1227 TYR A C      1 ? 
ATOM   3330 O O      . TYR A 1 219 ? 30.51   -4.684  9.726   1    17.288 ? 1227 TYR A O      1 ? 
ATOM   3331 C CB     . TYR A 1 219 ? 31.538  -6.193  11.778  1    21.76  ? 1227 TYR A CB     1 ? 
ATOM   3332 C CG     . TYR A 1 219 ? 32.325  -6.89   12.864  1    21.609 ? 1227 TYR A CG     1 ? 
ATOM   3333 C CD1    . TYR A 1 219 ? 33.617  -7.336  12.636  1    26.029 ? 1227 TYR A CD1    1 ? 
ATOM   3334 C CD2    . TYR A 1 219 ? 31.781  -7.079  14.128  1    23.875 ? 1227 TYR A CD2    1 ? 
ATOM   3335 C CE1    . TYR A 1 219 ? 34.346  -7.961  13.631  1    25.979 ? 1227 TYR A CE1    1 ? 
ATOM   3336 C CE2    . TYR A 1 219 ? 32.496  -7.689  15.134  1    25.685 ? 1227 TYR A CE2    1 ? 
ATOM   3337 C CZ     . TYR A 1 219 ? 33.78   -8.138  14.878  1    28.085 ? 1227 TYR A CZ     1 ? 
ATOM   3338 O OH     . TYR A 1 219 ? 34.497  -8.754  15.875  1    31.766 ? 1227 TYR A OH     1 ? 
ATOM   3339 H H      . TYR A 1 219 ? 30.378  -3.885  13.127  1    16.245 ? 1227 TYR A H      1 ? 
ATOM   3340 H HA     . TYR A 1 219 ? 32.92   -4.567  11.669  1    19.527 ? 1227 TYR A HA     1 c 
ATOM   3341 H HB2    . TYR A 1 219 ? 30.471  -6.336  11.956  1    21.17  ? 1227 TYR A HB2    1 c 
ATOM   3342 H HB3    . TYR A 1 219 ? 31.795  -6.628  10.811  1    21.112 ? 1227 TYR A HB3    1 c 
ATOM   3343 H HD1    . TYR A 1 219 ? 34.063  -7.197  11.657  1    24.988 ? 1227 TYR A HD1    1 c 
ATOM   3344 H HD2    . TYR A 1 219 ? 30.775  -6.727  14.331  1    23.797 ? 1227 TYR A HD2    1 c 
ATOM   3345 H HE1    . TYR A 1 219 ? 35.354  -8.309  13.435  1    26.408 ? 1227 TYR A HE1    1 c 
ATOM   3346 H HE2    . TYR A 1 219 ? 32.051  -7.833  16.113  1    25.769 ? 1227 TYR A HE2    1 c 
ATOM   3347 H HH     . TYR A 1 219 ? 34.002  -8.752  16.713  1    28.768 ? 1227 TYR A HH     1 ? 
ATOM   3348 N N      . PRO A 1 220 ? 31.415  -2.72   10.346  1    18.842 ? 1228 PRO A N      1 ? 
ATOM   3349 C CA     . PRO A 1 220 ? 30.726  -2.004  9.271   1    18.148 ? 1228 PRO A CA     1 ? 
ATOM   3350 C C      . PRO A 1 220 ? 31.065  -2.495  7.869   1    16.85  ? 1228 PRO A C      1 ? 
ATOM   3351 O O      . PRO A 1 220 ? 30.285  -2.262  6.936   1    17.753 ? 1228 PRO A O      1 ? 
ATOM   3352 C CB     . PRO A 1 220 ? 31.16   -0.554  9.469   1    19.59  ? 1228 PRO A CB     1 ? 
ATOM   3353 C CG     . PRO A 1 220 ? 32.508  -0.682  10.151  1    19.478 ? 1228 PRO A CG     1 ? 
ATOM   3354 C CD     . PRO A 1 220 ? 32.346  -1.847  11.081  1    20.166 ? 1228 PRO A CD     1 ? 
ATOM   3355 H HA     . PRO A 1 220 ? 29.647  -2.08   9.426   1    18.281 ? 1228 PRO A HA     1 c 
ATOM   3356 H HB2    . PRO A 1 220 ? 31.252  -0.039  8.511   1    19.247 ? 1228 PRO A HB2    1 c 
ATOM   3357 H HB3    . PRO A 1 220 ? 30.45   -0.015  10.1    1    19.246 ? 1228 PRO A HB3    1 c 
ATOM   3358 H HG2    . PRO A 1 220 ? 33.297  -0.876  9.423   1    19.651 ? 1228 PRO A HG2    1 c 
ATOM   3359 H HG3    . PRO A 1 220 ? 32.753  0.224   10.706  1    19.651 ? 1228 PRO A HG3    1 c 
ATOM   3360 H HD2    . PRO A 1 220 ? 33.298  -2.353  11.257  1    19.716 ? 1228 PRO A HD2    1 c 
ATOM   3361 H HD3    . PRO A 1 220 ? 31.917  -1.539  12.037  1    19.716 ? 1228 PRO A HD3    1 c 
ATOM   3362 N N      . ASP A 1 221 ? 32.214  -3.15   7.701   1    17.58  ? 1229 ASP A N      1 ? 
ATOM   3363 C CA     . ASP A 1 221 ? 32.589  -3.668  6.399   1    17.543 ? 1229 ASP A CA     1 ? 
ATOM   3364 C C      . ASP A 1 221 ? 32.235  -5.143  6.211   1    17.746 ? 1229 ASP A C      1 ? 
ATOM   3365 O O      . ASP A 1 221 ? 32.523  -5.701  5.15    1    18.918 ? 1229 ASP A O      1 ? 
ATOM   3366 C CB     . ASP A 1 221 ? 34.069  -3.445  6.13    1    20.655 ? 1229 ASP A CB     1 ? 
ATOM   3367 C CG     . ASP A 1 221 ? 34.324  -3.118  4.662   1    21.082 ? 1229 ASP A CG     1 ? 
ATOM   3368 O OD1    . ASP A 1 221 ? 33.461  -2.397  4.024   1    20.03  ? 1229 ASP A OD1    1 ? 
ATOM   3369 O OD2    . ASP A 1 221 ? 35.374  -3.582  4.161   1    22.696 ? 1229 ASP A OD2    1 ? 
ATOM   3370 H H      . ASP A 1 221 ? 32.838  -3.354  8.506   1    16.886 ? 1229 ASP A H      1 ? 
ATOM   3371 H HA     . ASP A 1 221 ? 32.043  -3.099  5.646   1    18.132 ? 1229 ASP A HA     1 c 
ATOM   3372 H HB2    . ASP A 1 221 ? 34.432  -2.619  6.745   1    20.019 ? 1229 ASP A HB2    1 c 
ATOM   3373 H HB3    . ASP A 1 221 ? 34.629  -4.345  6.394   1    20.008 ? 1229 ASP A HB3    1 c 
ATOM   3374 N N      . ASN A 1 222 ? 31.6    -5.778  7.199   1    17.246 ? 1230 ASN A N      1 ? 
ATOM   3375 C CA     . ASN A 1 222 ? 31.274  -7.194  7.11    1    15.795 ? 1230 ASN A CA     1 ? 
ATOM   3376 C C      . ASN A 1 222 ? 29.818  -7.516  7.422   1    14.89  ? 1230 ASN A C      1 ? 
ATOM   3377 O O      . ASN A 1 222 ? 29.424  -8.675  7.263   1    15.537 ? 1230 ASN A O      1 ? 
ATOM   3378 C CB     . ASN A 1 222 ? 32.174  -8.032  8.025   1    16.117 ? 1230 ASN A CB     1 ? 
ATOM   3379 C CG     . ASN A 1 222 ? 33.649  -7.855  7.712   1    17.716 ? 1230 ASN A CG     1 ? 
ATOM   3380 O OD1    . ASN A 1 222 ? 34.317  -6.981  8.271   1    18.568 ? 1230 ASN A OD1    1 ? 
ATOM   3381 N ND2    . ASN A 1 222 ? 34.177  -8.67   6.816   1    17.567 ? 1230 ASN A ND2    1 ? 
ATOM   3382 H H      . ASN A 1 222 ? 31.26   -5.245  8.022   1    15.962 ? 1230 ASN A H      1 ? 
ATOM   3383 H HA     . ASN A 1 222 ? 31.47   -7.519  6.086   1    15.976 ? 1230 ASN A HA     1 c 
ATOM   3384 H HB2    . ASN A 1 222 ? 31.993  -7.746  9.063   1    16.419 ? 1230 ASN A HB2    1 c 
ATOM   3385 H HB3    . ASN A 1 222 ? 31.911  -9.086  7.916   1    16.385 ? 1230 ASN A HB3    1 c 
ATOM   3386 H HD21   . ASN A 1 222 ? 35.152  -8.662  6.643   1    18.6   ? 1230 ASN A HD21   1 ? 
ATOM   3387 H HD22   . ASN A 1 222 ? 33.514  -9.232  6.295   1    17.978 ? 1230 ASN A HD22   1 ? 
ATOM   3388 N N      . PHE A 1 223 ? 29.017  -6.541  7.846   1    14.347 ? 1231 PHE A N      1 ? 
ATOM   3389 C CA     . PHE A 1 223 ? 27.646  -6.786  8.259   1    15.093 ? 1231 PHE A CA     1 ? 
ATOM   3390 C C      . PHE A 1 223 ? 26.751  -5.689  7.711   1    15.09  ? 1231 PHE A C      1 ? 
ATOM   3391 O O      . PHE A 1 223 ? 27.087  -4.508  7.81    1    18.443 ? 1231 PHE A O      1 ? 
ATOM   3392 C CB     . PHE A 1 223 ? 27.517  -6.819  9.786   1    14.386 ? 1231 PHE A CB     1 ? 
ATOM   3393 C CG     . PHE A 1 223 ? 26.111  -7.076  10.257  1    13.813 ? 1231 PHE A CG     1 ? 
ATOM   3394 C CD1    . PHE A 1 223 ? 25.501  -8.288  9.989   1    14.774 ? 1231 PHE A CD1    1 ? 
ATOM   3395 C CD2    . PHE A 1 223 ? 25.4    -6.109  10.948  1    14.567 ? 1231 PHE A CD2    1 ? 
ATOM   3396 C CE1    . PHE A 1 223 ? 24.205  -8.548  10.401  1    15.543 ? 1231 PHE A CE1    1 ? 
ATOM   3397 C CE2    . PHE A 1 223 ? 24.101  -6.366  11.389  1    15.726 ? 1231 PHE A CE2    1 ? 
ATOM   3398 C CZ     . PHE A 1 223 ? 23.501  -7.591  11.111  1    14.579 ? 1231 PHE A CZ     1 ? 
ATOM   3399 H H      . PHE A 1 223 ? 29.397  -5.588  7.994   1    14.342 ? 1231 PHE A H      1 ? 
ATOM   3400 H HA     . PHE A 1 223 ? 27.323  -7.743  7.857   1    14.818 ? 1231 PHE A HA     1 c 
ATOM   3401 H HB2    . PHE A 1 223 ? 28.171  -7.602  10.176  1    14.407 ? 1231 PHE A HB2    1 c 
ATOM   3402 H HB3    . PHE A 1 223 ? 27.856  -5.862  10.187  1    14.407 ? 1231 PHE A HB3    1 c 
ATOM   3403 H HD1    . PHE A 1 223 ? 26.048  -9.046  9.439   1    14.724 ? 1231 PHE A HD1    1 c 
ATOM   3404 H HD2    . PHE A 1 223 ? 25.868  -5.156  11.172  1    14.647 ? 1231 PHE A HD2    1 c 
ATOM   3405 H HE1    . PHE A 1 223 ? 23.751  -9.509  10.185  1    15.147 ? 1231 PHE A HE1    1 c 
ATOM   3406 H HE2    . PHE A 1 223 ? 23.553  -5.604  11.931  1    15.223 ? 1231 PHE A HE2    1 c 
ATOM   3407 H HZ     . PHE A 1 223 ? 22.486  -7.79   11.439  1    15.021 ? 1231 PHE A HZ     1 c 
ATOM   3408 N N      . ARG A 1 224 ? 25.604  -6.09   7.157   1    16.21  ? 1232 ARG A N      1 ? 
ATOM   3409 C CA     . ARG A 1 224 ? 24.544  -5.18   6.735   1    16.128 ? 1232 ARG A CA     1 ? 
ATOM   3410 C C      . ARG A 1 224 ? 23.232  -5.668  7.339   1    18.601 ? 1232 ARG A C      1 ? 
ATOM   3411 O O      . ARG A 1 224 ? 23.08   -6.854  7.628   1    18.122 ? 1232 ARG A O      1 ? 
ATOM   3412 C CB     . ARG A 1 224 ? 24.45   -5.095  5.212   1    17.963 ? 1232 ARG A CB     1 ? 
ATOM   3413 C CG     . ARG A 1 224 ? 25.694  -4.461  4.603   1    19.224 ? 1232 ARG A CG     1 ? 
ATOM   3414 C CD     . ARG A 1 224 ? 25.716  -4.519  3.083   1    18.43  ? 1232 ARG A CD     1 ? 
ATOM   3415 N NE     . ARG A 1 224 ? 24.729  -3.615  2.49    1    20.256 ? 1232 ARG A NE     1 ? 
ATOM   3416 C CZ     . ARG A 1 224 ? 24.747  -3.249  1.214   1    19.843 ? 1232 ARG A CZ     1 ? 
ATOM   3417 N NH1    . ARG A 1 224 ? 25.694  -3.661  0.398   1    20.659 ? 1232 ARG A NH1    1 ? 
ATOM   3418 N NH2    . ARG A 1 224 ? 23.795  -2.47   0.747   1    22.597 ? 1232 ARG A NH2    1 ? 
ATOM   3419 H H      . ARG A 1 224 ? 25.404  -7.109  7.111   1    13.754 ? 1232 ARG A H      1 ? 
ATOM   3420 H HA     . ARG A 1 224 ? 24.762  -4.187  7.131   1    16.885 ? 1232 ARG A HA     1 c 
ATOM   3421 H HB2    . ARG A 1 224 ? 24.324  -6.099  4.803   1    17.794 ? 1232 ARG A HB2    1 c 
ATOM   3422 H HB3    . ARG A 1 224 ? 23.574  -4.504  4.937   1    17.816 ? 1232 ARG A HB3    1 c 
ATOM   3423 H HG2    . ARG A 1 224 ? 25.752  -3.417  4.916   1    18.761 ? 1232 ARG A HG2    1 c 
ATOM   3424 H HG3    . ARG A 1 224 ? 26.58   -4.972  4.987   1    18.733 ? 1232 ARG A HG3    1 c 
ATOM   3425 H HD2    . ARG A 1 224 ? 26.711  -4.246  2.732   1    19.016 ? 1232 ARG A HD2    1 c 
ATOM   3426 H HD3    . ARG A 1 224 ? 25.511  -5.541  2.757   1    19.003 ? 1232 ARG A HD3    1 c 
ATOM   3427 H HE     . ARG A 1 224 ? 23.876  -3.408  3.028   1    18.122 ? 1232 ARG A HE     1 ? 
ATOM   3428 H HH11   . ARG A 1 224 ? 26.59   -4.116  0.698   1    19.624 ? 1232 ARG A HH11   1 ? 
ATOM   3429 H HH12   . ARG A 1 224 ? 25.562  -3.455  -0.581  1    19.383 ? 1232 ARG A HH12   1 ? 
ATOM   3430 H HH21   . ARG A 1 224 ? 23.086  -2.053  1.342   1    24.031 ? 1232 ARG A HH21   1 ? 
ATOM   3431 H HH22   . ARG A 1 224 ? 23.816  -2.302  -0.24   1    24.137 ? 1232 ARG A HH22   1 ? 
ATOM   3432 N N      . TYR A 1 225 ? 22.282  -4.748  7.521   1    16.085 ? 1233 TYR A N      1 ? 
ATOM   3433 C CA     . TYR A 1 225 ? 21.079  -5.033  8.297   1    16.475 ? 1233 TYR A CA     1 ? 
ATOM   3434 C C      . TYR A 1 225 ? 19.954  -4.146  7.792   1    17.764 ? 1233 TYR A C      1 ? 
ATOM   3435 O O      . TYR A 1 225 ? 20.074  -2.923  7.838   1    18.161 ? 1233 TYR A O      1 ? 
ATOM   3436 C CB     . TYR A 1 225 ? 21.358  -4.724  9.769   1    15.68  ? 1233 TYR A CB     1 ? 
ATOM   3437 C CG     . TYR A 1 225 ? 20.238  -4.933  10.773  1    15.546 ? 1233 TYR A CG     1 ? 
ATOM   3438 C CD1    . TYR A 1 225 ? 19.312  -5.962  10.65   1    16.418 ? 1233 TYR A CD1    1 ? 
ATOM   3439 C CD2    . TYR A 1 225 ? 20.165  -4.126  11.896  1    16.702 ? 1233 TYR A CD2    1 ? 
ATOM   3440 C CE1    . TYR A 1 225 ? 18.317  -6.156  11.608  1    16.673 ? 1233 TYR A CE1    1 ? 
ATOM   3441 C CE2    . TYR A 1 225 ? 19.189  -4.313  12.869  1    17.783 ? 1233 TYR A CE2    1 ? 
ATOM   3442 C CZ     . TYR A 1 225 ? 18.259  -5.323  12.716  1    18.481 ? 1233 TYR A CZ     1 ? 
ATOM   3443 O OH     . TYR A 1 225 ? 17.296  -5.52   13.676  1    19.146 ? 1233 TYR A OH     1 ? 
ATOM   3444 H H      . TYR A 1 225 ? 22.507  -3.773  7.296   1    17.806 ? 1233 TYR A H      1 ? 
ATOM   3445 H HA     . TYR A 1 225 ? 20.807  -6.081  8.185   1    16.476 ? 1233 TYR A HA     1 c 
ATOM   3446 H HB2    . TYR A 1 225 ? 22.208  -5.332  10.079  1    15.82  ? 1233 TYR A HB2    1 c 
ATOM   3447 H HB3    . TYR A 1 225 ? 21.683  -3.683  9.834   1    15.821 ? 1233 TYR A HB3    1 c 
ATOM   3448 H HD1    . TYR A 1 225 ? 19.353  -6.616  9.786   1    16.304 ? 1233 TYR A HD1    1 c 
ATOM   3449 H HD2    . TYR A 1 225 ? 20.893  -3.331  12.025  1    16.68  ? 1233 TYR A HD2    1 c 
ATOM   3450 H HE1    . TYR A 1 225 ? 17.595  -6.957  11.49   1    16.997 ? 1233 TYR A HE1    1 c 
ATOM   3451 H HE2    . TYR A 1 225 ? 19.146  -3.658  13.733  1    17.673 ? 1233 TYR A HE2    1 c 
ATOM   3452 H HH     . TYR A 1 225 ? 17.266  -4.795  14.345  1    19.523 ? 1233 TYR A HH     1 ? 
ATOM   3453 N N      . ASP A 1 226 ? 18.871  -4.756  7.324   1    16.29  ? 1234 ASP A N      1 ? 
ATOM   3454 C CA     . ASP A 1 226 ? 17.735  -4.023  6.787   1    18.314 ? 1234 ASP A CA     1 ? 
ATOM   3455 C C      . ASP A 1 226 ? 16.454  -4.59   7.363   1    16.038 ? 1234 ASP A C      1 ? 
ATOM   3456 O O      . ASP A 1 226 ? 16.284  -5.811  7.447   1    14.936 ? 1234 ASP A O      1 ? 
ATOM   3457 C CB     . ASP A 1 226 ? 17.711  -4.046  5.268   1    17.592 ? 1234 ASP A CB     1 ? 
ATOM   3458 C CG     . ASP A 1 226 ? 18.812  -3.207  4.668   1    19.48  ? 1234 ASP A CG     1 ? 
ATOM   3459 O OD1    . ASP A 1 226 ? 18.614  -1.973  4.572   1    18.329 ? 1234 ASP A OD1    1 ? 
ATOM   3460 O OD2    . ASP A 1 226 ? 19.871  -3.756  4.322   1    16.263 ? 1234 ASP A OD2    1 ? 
ATOM   3461 H H      . ASP A 1 226 ? 18.829  -5.794  7.359   1    16.125 ? 1234 ASP A H      1 ? 
ATOM   3462 H HA     . ASP A 1 226 ? 17.82   -2.981  7.1     1    17.377 ? 1234 ASP A HA     1 c 
ATOM   3463 H HB2    . ASP A 1 226 ? 17.825  -5.075  4.921   1    18.163 ? 1234 ASP A HB2    1 c 
ATOM   3464 H HB3    . ASP A 1 226 ? 16.75   -3.668  4.916   1    18.216 ? 1234 ASP A HB3    1 c 
ATOM   3465 N N      . LYS A 1 227 ? 15.521  -3.715  7.745   1    17.622 ? 1235 LYS A N      1 ? 
ATOM   3466 C CA     . LYS A 1 227 ? 14.286  -4.137  8.39    1    18.857 ? 1235 LYS A CA     1 ? 
ATOM   3467 C C      . LYS A 1 227 ? 13.072  -3.686  7.6     1    19.59  ? 1235 LYS A C      1 ? 
ATOM   3468 O O      . LYS A 1 227 ? 13.125  -2.643  6.956   1    20.094 ? 1235 LYS A O      1 ? 
ATOM   3469 C CB     . LYS A 1 227 ? 14.19   -3.499  9.789   1    19.336 ? 1235 LYS A CB     1 ? 
ATOM   3470 C CG     . LYS A 1 227 ? 15.161  -4.045  10.838  1    19.254 ? 1235 LYS A CG     1 ? 
ATOM   3471 C CD     . LYS A 1 227 ? 15.37   -3.111  12.032  1    20.467 ? 1235 LYS A CD     1 ? 
ATOM   3472 C CE     . LYS A 1 227 ? 16.457  -2.08   11.838  1    19.056 ? 1235 LYS A CE     1 ? 
ATOM   3473 N NZ     . LYS A 1 227 ? 16.593  -1.372  13.104  1    22.132 ? 1235 LYS A NZ     1 ? 
ATOM   3474 H H      . LYS A 1 227 ? 15.724  -2.705  7.665   1    18.597 ? 1235 LYS A H      1 ? 
ATOM   3475 H HA     . LYS A 1 227 ? 14.281  -5.224  8.473   1    18.77  ? 1235 LYS A HA     1 c 
ATOM   3476 H HB2    . LYS A 1 227 ? 14.363  -2.425  9.69    1    19.213 ? 1235 LYS A HB2    1 c 
ATOM   3477 H HB3    . LYS A 1 227 ? 13.173  -3.635  10.161  1    19.213 ? 1235 LYS A HB3    1 c 
ATOM   3478 H HG2    . LYS A 1 227 ? 14.78   -5.003  11.199  1    19.529 ? 1235 LYS A HG2    1 c 
ATOM   3479 H HG3    . LYS A 1 227 ? 16.125  -4.229  10.358  1    19.529 ? 1235 LYS A HG3    1 c 
ATOM   3480 H HD2    . LYS A 1 227 ? 14.43   -2.595  12.239  1    19.881 ? 1235 LYS A HD2    1 c 
ATOM   3481 H HD3    . LYS A 1 227 ? 15.611  -3.717  12.907  1    19.883 ? 1235 LYS A HD3    1 c 
ATOM   3482 H HE2    . LYS A 1 227 ? 17.403  -2.562  11.58   1    20.027 ? 1235 LYS A HE2    1 c 
ATOM   3483 H HE3    . LYS A 1 227 ? 16.183  -1.377  11.049  1    20.07  ? 1235 LYS A HE3    1 c 
ATOM   3484 H HZ1    . LYS A 1 227 ? 17.493  -0.885  13.163  1    21.644 ? 1235 LYS A HZ1    1 ? 
ATOM   3485 H HZ2    . LYS A 1 227 ? 15.857  -0.686  13.269  1    21.57  ? 1235 LYS A HZ2    1 ? 
ATOM   3486 H HZ3    . LYS A 1 227 ? 16.485  -2.089  13.806  1    20.594 ? 1235 LYS A HZ3    1 ? 
ATOM   3487 N N      . ALA A 1 228 ? 12.013  -4.497  7.662   1    20.454 ? 1236 ALA A N      1 ? 
ATOM   3488 C CA     . ALA A 1 228 ? 10.704  -4.149  7.118   1    19.965 ? 1236 ALA A CA     1 ? 
ATOM   3489 C C      . ALA A 1 228 ? 9.64    -4.196  8.205   1    19.848 ? 1236 ALA A C      1 ? 
ATOM   3490 O O      . ALA A 1 228 ? 9.464   -5.249  8.803   1    22.21  ? 1236 ALA A O      1 ? 
ATOM   3491 C CB     . ALA A 1 228 ? 10.306  -5.116  6.026   1    19.569 ? 1236 ALA A CB     1 ? 
ATOM   3492 H H      . ALA A 1 228 ? 12.137  -5.42   8.118   1    19.022 ? 1236 ALA A H      1 ? 
ATOM   3493 H HA     . ALA A 1 228 ? 10.75   -3.138  6.713   1    19.916 ? 1236 ALA A HA     1 c 
ATOM   3494 H HB1    . ALA A 1 228 ? 9.333   -4.835  5.625   1    19.681 ? 1236 ALA A HB1    1 c 
ATOM   3495 H HB2    . ALA A 1 228 ? 11.048  -5.091  5.224   1    19.683 ? 1236 ALA A HB2    1 c 
ATOM   3496 H HB3    . ALA A 1 228 ? 10.25   -6.128  6.433   1    19.7   ? 1236 ALA A HB3    1 c 
ATOM   3497 N N      A LEU A 1 229 ? 8.732   -3.207  8.294   0.5  20.296 ? 1237 LEU A N      1 ? 
ATOM   3498 N N      B LEU A 1 229 ? 9.238   -2.971  8.593   0.5  20.309 ? 1237 LEU A N      1 ? 
ATOM   3499 C CA     A LEU A 1 229 ? 7.607   -3.309  9.225   0.5  19.047 ? 1237 LEU A CA     1 ? 
ATOM   3500 C CA     B LEU A 1 229 ? 8.252   -2.719  9.629   0.5  19.282 ? 1237 LEU A CA     1 ? 
ATOM   3501 C C      A LEU A 1 229 ? 6.249   -3.273  8.519   0.5  19.153 ? 1237 LEU A C      1 ? 
ATOM   3502 C C      B LEU A 1 229 ? 6.951   -2.352  8.936   0.5  19.981 ? 1237 LEU A C      1 ? 
ATOM   3503 O O      A LEU A 1 229 ? 5.849   -2.221  8.04    0.5  18.849 ? 1237 LEU A O      1 ? 
ATOM   3504 O O      B LEU A 1 229 ? 6.702   -1.187  8.642   0.5  19.6   ? 1237 LEU A O      1 ? 
ATOM   3505 C CB     A LEU A 1 229 ? 7.814   -2.138  10.175  0.5  18.379 ? 1237 LEU A CB     1 ? 
ATOM   3506 C CB     B LEU A 1 229 ? 8.743   -1.611  10.558  0.5  19.24  ? 1237 LEU A CB     1 ? 
ATOM   3507 C CG     A LEU A 1 229 ? 9.217   -2.08   10.786  0.5  18.031 ? 1237 LEU A CG     1 ? 
ATOM   3508 C CG     B LEU A 1 229 ? 10.174  -1.769  11.078  0.5  19.428 ? 1237 LEU A CG     1 ? 
ATOM   3509 C CD1    A LEU A 1 229 ? 9.448   -0.884  11.658  0.5  17.441 ? 1237 LEU A CD1    1 ? 
ATOM   3510 C CD1    B LEU A 1 229 ? 10.59   -0.61   11.96   0.5  20.58  ? 1237 LEU A CD1    1 ? 
ATOM   3511 C CD2    A LEU A 1 229 ? 9.468   -3.364  11.56   0.5  17.904 ? 1237 LEU A CD2    1 ? 
ATOM   3512 C CD2    B LEU A 1 229 ? 10.302  -3.083  11.802  0.5  19.413 ? 1237 LEU A CD2    1 ? 
ATOM   3513 H H      A LEU A 1 229 ? 8.85    -2.336  7.744   0.5  20.21  ? 1237 LEU A H      1 ? 
ATOM   3514 H H      B LEU A 1 229 ? 9.677   -2.149  8.136   0.5  18.581 ? 1237 LEU A H      1 ? 
ATOM   3515 H HA     A LEU A 1 229 ? 7.695   -4.24   9.779   0.5  19.241 ? 1237 LEU A HA     1 c 
ATOM   3516 H HA     B LEU A 1 229 ? 8.104   -3.636  10.203  0.5  19.602 ? 1237 LEU A HA     1 c 
ATOM   3517 H HB2    A LEU A 1 229 ? 7.634   -1.211  9.626   0.5  18.457 ? 1237 LEU A HB2    1 c 
ATOM   3518 H HB2    B LEU A 1 229 ? 8.674   -0.661  10.023  0.5  19.29  ? 1237 LEU A HB2    1 c 
ATOM   3519 H HB3    A LEU A 1 229 ? 7.084   -2.214  10.982  0.5  18.497 ? 1237 LEU A HB3    1 c 
ATOM   3520 H HB3    B LEU A 1 229 ? 8.069   -1.56   11.416  0.5  19.29  ? 1237 LEU A HB3    1 c 
ATOM   3521 H HG     A LEU A 1 229 ? 9.939   -2.038  9.968   0.5  17.968 ? 1237 LEU A HG     1 c 
ATOM   3522 H HG     B LEU A 1 229 ? 10.845  -1.794  10.217  0.5  19.595 ? 1237 LEU A HG     1 c 
ATOM   3523 H HD11   A LEU A 1 229 ? 10.466  -0.91   12.052  0.5  17.61  ? 1237 LEU A HD11   1 c 
ATOM   3524 H HD11   B LEU A 1 229 ? 11.6    -0.782  12.335  0.5  20.374 ? 1237 LEU A HD11   1 c 
ATOM   3525 H HD12   A LEU A 1 229 ? 9.31    0.027   11.072  0.5  17.61  ? 1237 LEU A HD12   1 c 
ATOM   3526 H HD12   B LEU A 1 229 ? 10.571  0.316   11.381  0.5  20.276 ? 1237 LEU A HD12   1 c 
ATOM   3527 H HD13   A LEU A 1 229 ? 8.738   -0.894  12.487  0.5  17.626 ? 1237 LEU A HD13   1 c 
ATOM   3528 H HD13   B LEU A 1 229 ? 9.9     -0.525  12.802  0.5  20.253 ? 1237 LEU A HD13   1 c 
ATOM   3529 H HD21   A LEU A 1 229 ? 10.485  -3.359  11.957  0.5  17.958 ? 1237 LEU A HD21   1 c 
ATOM   3530 H HD21   B LEU A 1 229 ? 11.318  -3.189  12.186  0.5  19.445 ? 1237 LEU A HD21   1 c 
ATOM   3531 H HD22   A LEU A 1 229 ? 8.757   -3.438  12.384  0.5  17.978 ? 1237 LEU A HD22   1 c 
ATOM   3532 H HD22   B LEU A 1 229 ? 9.594   -3.112  12.634  0.5  19.423 ? 1237 LEU A HD22   1 c 
ATOM   3533 H HD23   A LEU A 1 229 ? 9.342   -4.222  10.898  0.5  17.994 ? 1237 LEU A HD23   1 c 
ATOM   3534 H HD23   B LEU A 1 229 ? 10.086  -3.902  11.114  0.5  19.419 ? 1237 LEU A HD23   1 c 
ATOM   3535 N N      A SER A 1 230 ? 5.514   -4.403  8.518   0.5  19.946 ? 1238 SER A N      1 ? 
ATOM   3536 N N      B SER A 1 230 ? 6.144   -3.386  8.708   0.5  20.376 ? 1238 SER A N      1 ? 
ATOM   3537 C CA     A SER A 1 230 ? 4.389   -4.609  7.616   0.5  20.906 ? 1238 SER A CA     1 ? 
ATOM   3538 C CA     B SER A 1 230 ? 5.165   -3.414  7.634   0.5  20.875 ? 1238 SER A CA     1 ? 
ATOM   3539 C C      A SER A 1 230 ? 3.239   -3.638  7.899   0.5  20.247 ? 1238 SER A C      1 ? 
ATOM   3540 C C      B SER A 1 230 ? 3.968   -2.526  7.965   0.5  19.765 ? 1238 SER A C      1 ? 
ATOM   3541 O O      A SER A 1 230 ? 2.559   -3.196  6.978   0.5  18.825 ? 1238 SER A O      1 ? 
ATOM   3542 O O      B SER A 1 230 ? 3.184   -2.193  7.081   0.5  20.71  ? 1238 SER A O      1 ? 
ATOM   3543 C CB     A SER A 1 230 ? 3.918   -6.04   7.683   0.5  21.396 ? 1238 SER A CB     1 ? 
ATOM   3544 C CB     B SER A 1 230 ? 4.706   -4.826  7.346   0.5  22.275 ? 1238 SER A CB     1 ? 
ATOM   3545 O OG     A SER A 1 230 ? 3.602   -6.41   9.02    0.5  21.69  ? 1238 SER A OG     1 ? 
ATOM   3546 O OG     B SER A 1 230 ? 3.735   -5.254  8.291   0.5  23.079 ? 1238 SER A OG     1 ? 
ATOM   3547 H H      A SER A 1 230 ? 5.753   -5.174  9.168   0.5  20.024 ? 1238 SER A H      1 ? 
ATOM   3548 H H      B SER A 1 230 ? 6.223   -4.203  9.339   0.5  21.209 ? 1238 SER A H      1 ? 
ATOM   3549 H HA     A SER A 1 230 ? 4.741   -4.419  6.6     0.5  20.69  ? 1238 SER A HA     1 c 
ATOM   3550 H HA     B SER A 1 230 ? 5.641   -3.019  6.735   0.5  20.82  ? 1238 SER A HA     1 c 
ATOM   3551 H HB2    A SER A 1 230 ? 3.034   -6.16   7.055   0.5  21.359 ? 1238 SER A HB2    1 c 
ATOM   3552 H HB2    B SER A 1 230 ? 4.279   -4.869  6.342   0.5  22.156 ? 1238 SER A HB2    1 c 
ATOM   3553 H HB3    A SER A 1 230 ? 4.7     -6.697  7.299   0.5  21.366 ? 1238 SER A HB3    1 c 
ATOM   3554 H HB3    B SER A 1 230 ? 5.561   -5.494  7.38    0.5  22.191 ? 1238 SER A HB3    1 c 
ATOM   3555 H HG     A SER A 1 230 ? 3.476   -7.374  9.058   0.5  21.234 ? 1238 SER A HG     1 ? 
ATOM   3556 H HG     B SER A 1 230 ? 3.254   -6.007  7.899   0.5  23.165 ? 1238 SER A HG     1 ? 
ATOM   3557 N N      A ARG A 1 231 ? 3.034   -3.316  9.181   0.5  20.59  ? 1239 ARG A N      1 ? 
ATOM   3558 N N      B ARG A 1 231 ? 3.834   -2.195  9.252   0.5  18.71  ? 1239 ARG A N      1 ? 
ATOM   3559 C CA     A ARG A 1 231 ? 1.871   -2.559  9.606   0.5  20.748 ? 1239 ARG A CA     1 ? 
ATOM   3560 C CA     B ARG A 1 231 ? 2.746   -1.365  9.751   0.5  20.296 ? 1239 ARG A CA     1 ? 
ATOM   3561 C C      A ARG A 1 231 ? 2.215   -1.081  9.798   0.5  21.012 ? 1239 ARG A C      1 ? 
ATOM   3562 C C      B ARG A 1 231 ? 3.178   0.098   9.883   0.5  20.086 ? 1239 ARG A C      1 ? 
ATOM   3563 O O      A ARG A 1 231 ? 1.321   -0.273  10.048  0.5  21.897 ? 1239 ARG A O      1 ? 
ATOM   3564 O O      B ARG A 1 231 ? 2.329   0.964   10.112  0.5  20.456 ? 1239 ARG A O      1 ? 
ATOM   3565 C CB     A ARG A 1 231 ? 1.309   -3.118  10.922  0.5  21.736 ? 1239 ARG A CB     1 ? 
ATOM   3566 C CB     B ARG A 1 231 ? 2.226   -1.825  11.122  0.5  19.868 ? 1239 ARG A CB     1 ? 
ATOM   3567 C CG     A ARG A 1 231 ? 0.782   -4.542  10.856  0.5  23.074 ? 1239 ARG A CG     1 ? 
ATOM   3568 C CG     B ARG A 1 231 ? 1.52    -3.178  11.143  0.5  21.044 ? 1239 ARG A CG     1 ? 
ATOM   3569 C CD     A ARG A 1 231 ? 0.048   -4.914  12.132  0.5  24.699 ? 1239 ARG A CD     1 ? 
ATOM   3570 C CD     B ARG A 1 231 ? 0.853   -3.464  12.476  0.5  22.954 ? 1239 ARG A CD     1 ? 
ATOM   3571 N NE     A ARG A 1 231 ? -0.387  -6.313  12.161  0.5  25.467 ? 1239 ARG A NE     1 ? 
ATOM   3572 N NE     B ARG A 1 231 ? 0.23    -4.791  12.589  0.5  24.944 ? 1239 ARG A NE     1 ? 
ATOM   3573 C CZ     A ARG A 1 231 ? -1.217  -6.844  13.05   0.5  26.406 ? 1239 ARG A CZ     1 ? 
ATOM   3574 C CZ     B ARG A 1 231 ? -0.596  -5.138  13.574  0.5  25.75  ? 1239 ARG A CZ     1 ? 
ATOM   3575 N NH1    A ARG A 1 231 ? -1.759  -6.144  14.032  0.5  26.593 ? 1239 ARG A NH1    1 ? 
ATOM   3576 N NH1    B ARG A 1 231 ? -0.895  -4.282  14.542  0.5  25.95  ? 1239 ARG A NH1    1 ? 
ATOM   3577 N NH2    A ARG A 1 231 ? -1.476  -8.123  12.96   0.5  26.923 ? 1239 ARG A NH2    1 ? 
ATOM   3578 N NH2    B ARG A 1 231 ? -1.121  -6.356  13.602  0.5  26.905 ? 1239 ARG A NH2    1 ? 
ATOM   3579 H H      A ARG A 1 231 ? 3.714   -3.631  9.895   0.5  19.455 ? 1239 ARG A H      1 ? 
ATOM   3580 H H      B ARG A 1 231 ? 4.521   -2.571  9.924   0.5  18.433 ? 1239 ARG A H      1 ? 
ATOM   3581 H HA     A ARG A 1 231 ? 1.106   -2.641  8.831   0.5  20.934 ? 1239 ARG A HA     1 c 
ATOM   3582 H HA     B ARG A 1 231 ? 1.923   -1.418  9.035   0.5  19.875 ? 1239 ARG A HA     1 c 
ATOM   3583 H HB2    A ARG A 1 231 ? 2.095   -3.075  11.678  0.5  21.832 ? 1239 ARG A HB2    1 c 
ATOM   3584 H HB2    B ARG A 1 231 ? 3.069   -1.862  11.815  0.5  20.253 ? 1239 ARG A HB2    1 c 
ATOM   3585 H HB3    A ARG A 1 231 ? 0.499   -2.465  11.254  0.5  21.808 ? 1239 ARG A HB3    1 c 
ATOM   3586 H HB3    B ARG A 1 231 ? 1.532   -1.068  11.495  0.5  20.222 ? 1239 ARG A HB3    1 c 
ATOM   3587 H HG2    A ARG A 1 231 ? 0.102   -4.641  10.007  0.5  23.429 ? 1239 ARG A HG2    1 c 
ATOM   3588 H HG2    B ARG A 1 231 ? 0.762   -3.199  10.357  0.5  21.19  ? 1239 ARG A HG2    1 c 
ATOM   3589 H HG3    A ARG A 1 231 ? 1.618   -5.229  10.711  0.5  23.466 ? 1239 ARG A HG3    1 c 
ATOM   3590 H HG3    B ARG A 1 231 ? 2.243   -3.967  10.931  0.5  21.22  ? 1239 ARG A HG3    1 c 
ATOM   3591 H HD2    A ARG A 1 231 ? 0.705   -4.727  12.984  0.5  24.506 ? 1239 ARG A HD2    1 c 
ATOM   3592 H HD2    B ARG A 1 231 ? 1.602   -3.359  13.263  0.5  22.948 ? 1239 ARG A HD2    1 c 
ATOM   3593 H HD3    A ARG A 1 231 ? -0.826  -4.267  12.237  0.5  24.506 ? 1239 ARG A HD3    1 c 
ATOM   3594 H HD3    B ARG A 1 231 ? 0.091   -2.701  12.647  0.5  22.948 ? 1239 ARG A HD3    1 c 
ATOM   3595 H HE     A ARG A 1 231 ? -0.046  -6.94   11.45   0.5  25.558 ? 1239 ARG A HE     1 ? 
ATOM   3596 H HE     B ARG A 1 231 ? 0.435   -5.492  11.879  0.5  24.2   ? 1239 ARG A HE     1 ? 
ATOM   3597 H HH11   A ARG A 1 231 ? -1.534  -5.161  14.175  0.5  25.332 ? 1239 ARG A HH11   1 ? 
ATOM   3598 H HH11   B ARG A 1 231 ? -0.449  -3.367  14.642  0.5  25.429 ? 1239 ARG A HH11   1 ? 
ATOM   3599 H HH12   A ARG A 1 231 ? -2.403  -6.633  14.652  0.5  26.476 ? 1239 ARG A HH12   1 ? 
ATOM   3600 H HH12   B ARG A 1 231 ? -1.562  -4.596  15.228  0.5  25.299 ? 1239 ARG A HH12   1 ? 
ATOM   3601 H HH21   A ARG A 1 231 ? -0.925  -8.649  12.28   0.5  27.33  ? 1239 ARG A HH21   1 ? 
ATOM   3602 H HH21   B ARG A 1 231 ? -0.917  -7.029  12.862  0.5  26.794 ? 1239 ARG A HH21   1 ? 
ATOM   3603 H HH22   A ARG A 1 231 ? -2.157  -8.55   13.588  0.5  25.331 ? 1239 ARG A HH22   1 ? 
ATOM   3604 H HH22   B ARG A 1 231 ? -1.737  -6.611  14.364  0.5  26.513 ? 1239 ARG A HH22   1 ? 
ATOM   3605 N N      A GLU A 1 232 ? 3.503   -0.72   9.675   0.5  20.4   ? 1240 GLU A N      1 ? 
ATOM   3606 N N      B GLU A 1 232 ? 4.48    0.39    9.76    0.5  21.585 ? 1240 GLU A N      1 ? 
ATOM   3607 C CA     A GLU A 1 232 ? 3.927   0.649   9.925   0.5  20.03  ? 1240 GLU A CA     1 ? 
ATOM   3608 C CA     B GLU A 1 232 ? 4.935   1.737   10.082  0.5  22.35  ? 1240 GLU A CA     1 ? 
ATOM   3609 C C      A GLU A 1 232 ? 4.593   1.219   8.678   0.5  18.603 ? 1240 GLU A C      1 ? 
ATOM   3610 C C      B GLU A 1 232 ? 5.907   2.307   9.045   0.5  21.781 ? 1240 GLU A C      1 ? 
ATOM   3611 O O      A GLU A 1 232 ? 4.92    2.398   8.637   0.5  18.573 ? 1240 GLU A O      1 ? 
ATOM   3612 O O      B GLU A 1 232 ? 6.381   3.432   9.191   0.5  21.736 ? 1240 GLU A O      1 ? 
ATOM   3613 C CB     A GLU A 1 232 ? 4.835   0.706   11.158  0.5  20.669 ? 1240 GLU A CB     1 ? 
ATOM   3614 C CB     B GLU A 1 232 ? 5.549   1.769   11.486  0.5  22.115 ? 1240 GLU A CB     1 ? 
ATOM   3615 C CG     A GLU A 1 232 ? 4.055   0.513   12.453  0.5  22.478 ? 1240 GLU A CG     1 ? 
ATOM   3616 C CG     B GLU A 1 232 ? 7.046   2.093   11.503  0.5  24.297 ? 1240 GLU A CG     1 ? 
ATOM   3617 C CD     A GLU A 1 232 ? 4.836   0.833   13.72   0.5  25.02  ? 1240 GLU A CD     1 ? 
ATOM   3618 C CD     B GLU A 1 232 ? 7.659   1.897   12.879  0.5  21.519 ? 1240 GLU A CD     1 ? 
ATOM   3619 O OE1    A GLU A 1 232 ? 6.04    1.155   13.583  0.5  24.369 ? 1240 GLU A OE1    1 ? 
ATOM   3620 O OE1    B GLU A 1 232 ? 8.489   2.693   13.363  0.5  20.232 ? 1240 GLU A OE1    1 ? 
ATOM   3621 O OE2    A GLU A 1 232 ? 4.249   0.746   14.831  0.5  22.395 ? 1240 GLU A OE2    1 ? 
ATOM   3622 O OE2    B GLU A 1 232 ? 7.213   0.905   13.489  0.5  22.313 ? 1240 GLU A OE2    1 ? 
ATOM   3623 H H      A GLU A 1 232 ? 4.209   -1.418  9.366   0.5  19.998 ? 1240 GLU A H      1 ? 
ATOM   3624 H H      B GLU A 1 232 ? 5.16    -0.337  9.468   0.5  20.467 ? 1240 GLU A H      1 ? 
ATOM   3625 H HA     A GLU A 1 232 ? 3.035   1.243   10.136  0.5  19.948 ? 1240 GLU A HA     1 c 
ATOM   3626 H HA     B GLU A 1 232 ? 4.056   2.384   10.101  0.5  22.06  ? 1240 GLU A HA     1 c 
ATOM   3627 H HB2    A GLU A 1 232 ? 5.597   -0.071  11.073  0.5  20.906 ? 1240 GLU A HB2    1 c 
ATOM   3628 H HB2    B GLU A 1 232 ? 5.021   2.517   12.083  0.5  22.625 ? 1240 GLU A HB2    1 c 
ATOM   3629 H HB3    A GLU A 1 232 ? 5.343   1.672   11.18   0.5  20.907 ? 1240 GLU A HB3    1 c 
ATOM   3630 H HB3    B GLU A 1 232 ? 5.394   0.797   11.959  0.5  22.625 ? 1240 GLU A HB3    1 c 
ATOM   3631 H HG2    A GLU A 1 232 ? 3.166   1.146   12.427  0.5  22.6   ? 1240 GLU A HG2    1 c 
ATOM   3632 H HG2    B GLU A 1 232 ? 7.564   1.447   10.791  0.5  23.181 ? 1240 GLU A HG2    1 c 
ATOM   3633 H HG3    A GLU A 1 232 ? 3.716   -0.524  12.51   0.5  22.616 ? 1240 GLU A HG3    1 c 
ATOM   3634 H HG3    B GLU A 1 232 ? 7.196   3.129   11.194  0.5  23.181 ? 1240 GLU A HG3    1 c 
ATOM   3635 N N      A GLN A 1 233 ? 4.755   0.361   7.658   0.5  18.65  ? 1241 GLN A N      1 ? 
ATOM   3636 N N      B GLN A 1 233 ? 6.218   1.531   8.011   0.5  21.122 ? 1241 GLN A N      1 ? 
ATOM   3637 C CA     A GLN A 1 233 ? 5.453   0.722   6.43    0.5  18.153 ? 1241 GLN A CA     1 ? 
ATOM   3638 C CA     B GLN A 1 233 ? 7.021   2.031   6.912   0.5  22.527 ? 1241 GLN A CA     1 ? 
ATOM   3639 C C      A GLN A 1 233 ? 4.693   0.142   5.237   0.5  18.194 ? 1241 GLN A C      1 ? 
ATOM   3640 C C      B GLN A 1 233 ? 6.335   1.777   5.574   0.5  22.043 ? 1241 GLN A C      1 ? 
ATOM   3641 O O      A GLN A 1 233 ? 3.957   -0.842  5.379   0.5  16.211 ? 1241 GLN A O      1 ? 
ATOM   3642 O O      B GLN A 1 233 ? 5.552   0.836   5.447   0.5  22.995 ? 1241 GLN A O      1 ? 
ATOM   3643 C CB     A GLN A 1 233 ? 6.894   0.215   6.375   0.5  18.089 ? 1241 GLN A CB     1 ? 
ATOM   3644 C CB     B GLN A 1 233 ? 8.359   1.298   6.896   0.5  23.35  ? 1241 GLN A CB     1 ? 
ATOM   3645 C CG     A GLN A 1 233 ? 7.767   0.599   7.573   0.5  17.803 ? 1241 GLN A CG     1 ? 
ATOM   3646 C CG     B GLN A 1 233 ? 9.408   1.83    7.867   0.5  23.683 ? 1241 GLN A CG     1 ? 
ATOM   3647 C CD     A GLN A 1 233 ? 9.179   0.041   7.497   0.5  18.605 ? 1241 GLN A CD     1 ? 
ATOM   3648 C CD     B GLN A 1 233 ? 10.593  0.894   7.915   0.5  24.648 ? 1241 GLN A CD     1 ? 
ATOM   3649 O OE1    A GLN A 1 233 ? 9.451   -0.971  6.846   0.5  18.857 ? 1241 GLN A OE1    1 ? 
ATOM   3650 O OE1    B GLN A 1 233 ? 10.584  -0.164  7.276   0.5  22.997 ? 1241 GLN A OE1    1 ? 
ATOM   3651 N NE2    A GLN A 1 233 ? 10.113  0.712   8.151   0.5  19.486 ? 1241 GLN A NE2    1 ? 
ATOM   3652 N NE2    B GLN A 1 233 ? 11.61   1.269   8.678   0.5  25.714 ? 1241 GLN A NE2    1 ? 
ATOM   3653 H H      A GLN A 1 233 ? 4.335   -0.584  7.731   0.5  16.659 ? 1241 GLN A H      1 ? 
ATOM   3654 H H      B GLN A 1 233 ? 5.935   0.538   8.018   0.5  20.373 ? 1241 GLN A H      1 ? 
ATOM   3655 H HA     A GLN A 1 233 ? 5.458   1.811   6.345   0.5  18.241 ? 1241 GLN A HA     1 c 
ATOM   3656 H HA     B GLN A 1 233 ? 7.177   3.104   7.045   0.5  22.309 ? 1241 GLN A HA     1 c 
ATOM   3657 H HB2    A GLN A 1 233 ? 6.872   -0.874  6.295   0.5  18.04  ? 1241 GLN A HB2    1 c 
ATOM   3658 H HB2    B GLN A 1 233 ? 8.176   0.245   7.123   0.5  23.239 ? 1241 GLN A HB2    1 c 
ATOM   3659 H HB3    A GLN A 1 233 ? 7.36    0.601   5.466   0.5  18.04  ? 1241 GLN A HB3    1 c 
ATOM   3660 H HB3    B GLN A 1 233 ? 8.765   1.347   5.883   0.5  23.239 ? 1241 GLN A HB3    1 c 
ATOM   3661 H HG2    A GLN A 1 233 ? 7.825   1.687   7.639   0.5  18.038 ? 1241 GLN A HG2    1 c 
ATOM   3662 H HG2    B GLN A 1 233 ? 9.737   2.821   7.546   0.5  23.818 ? 1241 GLN A HG2    1 c 
ATOM   3663 H HG3    A GLN A 1 233 ? 7.297   0.237   8.489   0.5  18.038 ? 1241 GLN A HG3    1 c 
ATOM   3664 H HG3    B GLN A 1 233 ? 8.974   1.921   8.865   0.5  23.818 ? 1241 GLN A HG3    1 c 
ATOM   3665 H HE21   A GLN A 1 233 ? 9.903   1.638   8.538   0.5  18.788 ? 1241 GLN A HE21   1 ? 
ATOM   3666 H HE21   B GLN A 1 233 ? 11.539  2.138   9.209   0.5  24.843 ? 1241 GLN A HE21   1 ? 
ATOM   3667 H HE22   A GLN A 1 233 ? 11.051  0.331   8.206   0.5  18.767 ? 1241 GLN A HE22   1 ? 
ATOM   3668 H HE22   B GLN A 1 233 ? 12.443  0.698   8.737   0.5  24.883 ? 1241 GLN A HE22   1 ? 
ATOM   3669 N N      A LYS A 1 234 ? 4.855   0.795   4.077   0.5  19     ? 1242 LYS A N      1 ? 
ATOM   3670 N N      B LYS A 1 234 ? 6.663   2.624   4.586   0.5  19.667 ? 1242 LYS A N      1 ? 
ATOM   3671 C CA     A LYS A 1 234 ? 4.33    0.298   2.814   0.5  20.802 ? 1242 LYS A CA     1 ? 
ATOM   3672 C CA     B LYS A 1 234 ? 6.155   2.53    3.231   0.5  21.315 ? 1242 LYS A CA     1 ? 
ATOM   3673 C C      A LYS A 1 234 ? 5.44    0.221   1.772   0.5  21.047 ? 1242 LYS A C      1 ? 
ATOM   3674 C C      B LYS A 1 234 ? 7.308   2.299   2.259   0.5  20.288 ? 1242 LYS A C      1 ? 
ATOM   3675 O O      A LYS A 1 234 ? 6.398   0.997   1.805   0.5  21.279 ? 1242 LYS A O      1 ? 
ATOM   3676 O O      B LYS A 1 234 ? 8.367   2.896   2.378   0.5  20.245 ? 1242 LYS A O      1 ? 
ATOM   3677 C CB     A LYS A 1 234 ? 3.301   1.237   2.186   0.5  21.014 ? 1242 LYS A CB     1 ? 
ATOM   3678 C CB     B LYS A 1 234 ? 5.485   3.837   2.786   0.5  21.714 ? 1242 LYS A CB     1 ? 
ATOM   3679 C CG     A LYS A 1 234 ? 2.14    1.627   3.072   0.5  20.905 ? 1242 LYS A CG     1 ? 
ATOM   3680 C CG     B LYS A 1 234 ? 4.142   4.124   3.39    0.5  24.635 ? 1242 LYS A CG     1 ? 
ATOM   3681 C CD     A LYS A 1 234 ? 1.268   0.488   3.574   0.5  20.942 ? 1242 LYS A CD     1 ? 
ATOM   3682 C CD     B LYS A 1 234 ? 3.205   2.92    3.391   0.5  27.497 ? 1242 LYS A CD     1 ? 
ATOM   3683 C CE     A LYS A 1 234 ? 0.089   1.059   4.302   0.5  21.271 ? 1242 LYS A CE     1 ? 
ATOM   3684 C CE     B LYS A 1 234 ? 1.773   3.309   3.186   0.5  31.471 ? 1242 LYS A CE     1 ? 
ATOM   3685 N NZ     A LYS A 1 234 ? -0.815  0.042   4.854   0.5  20.973 ? 1242 LYS A NZ     1 ? 
ATOM   3686 N NZ     B LYS A 1 234 ? 0.865   2.152   3.224   0.5  33.368 ? 1242 LYS A NZ     1 ? 
ATOM   3687 H H      A LYS A 1 234 ? 5.358   1.7     4.071   0.5  18.957 ? 1242 LYS A H      1 ? 
ATOM   3688 H H      B LYS A 1 234 ? 7.317   3.39    4.8     0.5  20.059 ? 1242 LYS A H      1 ? 
ATOM   3689 H HA     A LYS A 1 234 ? 3.902   -0.695  2.969   0.5  20.529 ? 1242 LYS A HA     1 c 
ATOM   3690 H HA     B LYS A 1 234 ? 5.451   1.697   3.17    0.5  20.878 ? 1242 LYS A HA     1 c 
ATOM   3691 H HB2    A LYS A 1 234 ? 3.812   2.149   1.872   0.5  20.944 ? 1242 LYS A HB2    1 c 
ATOM   3692 H HB2    B LYS A 1 234 ? 6.153   4.666   3.03    0.5  22.245 ? 1242 LYS A HB2    1 c 
ATOM   3693 H HB3    A LYS A 1 234 ? 2.901   0.76    1.289   0.5  20.944 ? 1242 LYS A HB3    1 c 
ATOM   3694 H HB3    B LYS A 1 234 ? 5.373   3.815   1.7     0.5  22.245 ? 1242 LYS A HB3    1 c 
ATOM   3695 H HG2    A LYS A 1 234 ? 2.538   2.165   3.935   0.5  20.938 ? 1242 LYS A HG2    1 c 
ATOM   3696 H HG2    B LYS A 1 234 ? 4.289   4.464   4.417   0.5  24.533 ? 1242 LYS A HG2    1 c 
ATOM   3697 H HG3    A LYS A 1 234 ? 1.512   2.327   2.518   0.5  20.938 ? 1242 LYS A HG3    1 c 
ATOM   3698 H HG3    B LYS A 1 234 ? 3.675   4.938   2.831   0.5  24.53  ? 1242 LYS A HG3    1 c 
ATOM   3699 H HD2    A LYS A 1 234 ? 0.92    -0.112  2.73    0.5  21.006 ? 1242 LYS A HD2    1 c 
ATOM   3700 H HD2    B LYS A 1 234 ? 3.505   2.236   2.595   0.5  27.666 ? 1242 LYS A HD2    1 c 
ATOM   3701 H HD3    A LYS A 1 234 ? 1.842   -0.148  4.251   0.5  21.006 ? 1242 LYS A HD3    1 c 
ATOM   3702 H HD3    B LYS A 1 234 ? 3.301   2.391   4.341   0.5  27.67  ? 1242 LYS A HD3    1 c 
ATOM   3703 H HE2    A LYS A 1 234 ? 0.443   1.698   5.114   0.5  21.446 ? 1242 LYS A HE2    1 c 
ATOM   3704 H HE2    B LYS A 1 234 ? 1.464   4.034   3.94    0.5  30.971 ? 1242 LYS A HE2    1 c 
ATOM   3705 H HE3    A LYS A 1 234 ? -0.478  1.687   3.613   0.5  21.192 ? 1242 LYS A HE3    1 c 
ATOM   3706 H HE3    B LYS A 1 234 ? 1.678   3.79    2.211   0.5  30.958 ? 1242 LYS A HE3    1 c 
ATOM   3707 H HZ1    A LYS A 1 234 ? -1.326  -0.413  4.081   0.5  19.761 ? 1242 LYS A HZ1    1 ? 
ATOM   3708 H HZ1    B LYS A 1 234 ? 1.097   1.517   2.467   0.5  33.952 ? 1242 LYS A HZ1    1 ? 
ATOM   3709 H HZ2    A LYS A 1 234 ? -0.27   -0.653  5.388   0.5  20.69  ? 1242 LYS A HZ2    1 ? 
ATOM   3710 H HZ2    B LYS A 1 234 ? 0.966   1.671   4.114   0.5  32.678 ? 1242 LYS A HZ2    1 ? 
ATOM   3711 H HZ3    A LYS A 1 234 ? -1.502  0.47    5.469   0.5  21.088 ? 1242 LYS A HZ3    1 ? 
ATOM   3712 H HZ3    B LYS A 1 234 ? -0.086  2.482   3.104   0.5  33.964 ? 1242 LYS A HZ3    1 ? 
ATOM   3713 N N      A ASN A 1 235 ? 5.276   -0.717  0.834   0.5  20.847 ? 1243 ASN A N      1 ? 
ATOM   3714 N N      B ASN A 1 235 ? 7.065   1.442   1.277   0.5  22.103 ? 1243 ASN A N      1 ? 
ATOM   3715 C CA     A ASN A 1 235 ? 6.195   -0.827  -0.286  0.5  18.649 ? 1243 ASN A CA     1 ? 
ATOM   3716 C CA     B ASN A 1 235 ? 7.993   1.246   0.186   0.5  25.294 ? 1243 ASN A CA     1 ? 
ATOM   3717 C C      A ASN A 1 235 ? 5.833   0.227   -1.319  0.5  18.721 ? 1243 ASN A C      1 ? 
ATOM   3718 C C      B ASN A 1 235 ? 8.12    2.574   -0.54   0.5  27.525 ? 1243 ASN A C      1 ? 
ATOM   3719 O O      A ASN A 1 235 ? 4.798   0.891   -1.23   0.5  18.508 ? 1243 ASN A O      1 ? 
ATOM   3720 O O      B ASN A 1 235 ? 7.474   3.552   -0.178  0.5  28.682 ? 1243 ASN A O      1 ? 
ATOM   3721 C CB     A ASN A 1 235 ? 6.163   -2.184  -0.975  0.5  17.106 ? 1243 ASN A CB     1 ? 
ATOM   3722 C CB     B ASN A 1 235 ? 7.531   0.144   -0.772  0.5  24.551 ? 1243 ASN A CB     1 ? 
ATOM   3723 C CG     A ASN A 1 235 ? 4.777   -2.644  -1.334  0.5  18.052 ? 1243 ASN A CG     1 ? 
ATOM   3724 C CG     B ASN A 1 235 ? 8.6     -0.912  -0.961  0.5  26.892 ? 1243 ASN A CG     1 ? 
ATOM   3725 O OD1    A ASN A 1 235 ? 4.044   -1.92   -2.021  0.5  17.398 ? 1243 ASN A OD1    1 ? 
ATOM   3726 O OD1    B ASN A 1 235 ? 9.033   -1.194  -2.084  0.5  22.648 ? 1243 ASN A OD1    1 ? 
ATOM   3727 N ND2    A ASN A 1 235 ? 4.412   -3.866  -0.943  0.5  17.491 ? 1243 ASN A ND2    1 ? 
ATOM   3728 N ND2    B ASN A 1 235 ? 9.02    -1.535  0.134   0.5  26.929 ? 1243 ASN A ND2    1 ? 
ATOM   3729 H H      A ASN A 1 235 ? 4.455   -1.349  0.88    0.5  19.706 ? 1243 ASN A H      1 ? 
ATOM   3730 H H      B ASN A 1 235 ? 6.161   0.935   1.261   0.5  22.205 ? 1243 ASN A H      1 ? 
ATOM   3731 H HA     A ASN A 1 235 ? 7.212   -0.65   0.071   0.5  18.764 ? 1243 ASN A HA     1 c 
ATOM   3732 H HA     B ASN A 1 235 ? 8.964   0.959   0.594   0.5  24.896 ? 1243 ASN A HA     1 c 
ATOM   3733 H HB2    A ASN A 1 235 ? 6.761   -2.13   -1.885  0.5  17.745 ? 1243 ASN A HB2    1 c 
ATOM   3734 H HB2    B ASN A 1 235 ? 6.628   -0.324  -0.375  0.5  25.208 ? 1243 ASN A HB2    1 c 
ATOM   3735 H HB3    A ASN A 1 235 ? 6.621   -2.925  -0.317  0.5  17.66  ? 1243 ASN A HB3    1 c 
ATOM   3736 H HB3    B ASN A 1 235 ? 7.287   0.587   -1.74   0.5  25.208 ? 1243 ASN A HB3    1 c 
ATOM   3737 H HD21   A ASN A 1 235 ? 3.507   -4.199  -1.167  0.5  17.766 ? 1243 ASN A HD21   1 ? 
ATOM   3738 H HD21   B ASN A 1 235 ? 9.82    -2.15   0.1     0.5  26.391 ? 1243 ASN A HD21   1 ? 
ATOM   3739 H HD22   A ASN A 1 235 ? 5.013   -4.489  -0.466  0.5  18.418 ? 1243 ASN A HD22   1 ? 
ATOM   3740 H HD22   B ASN A 1 235 ? 8.571   -1.339  1.016   0.5  27.088 ? 1243 ASN A HD22   1 ? 
ATOM   3741 N N      A ARG A 1 236 ? 6.69    0.306   -2.317  0.5  19.131 ? 1244 ARG A N      1 ? 
ATOM   3742 N N      B ARG A 1 236 ? 8.944   2.58    -1.593  0.5  35.43  ? 1244 ARG A N      1 ? 
ATOM   3743 C CA     A ARG A 1 236 ? 6.567   1.178   -3.477  0.5  23.311 ? 1244 ARG A CA     1 ? 
ATOM   3744 C CA     B ARG A 1 236 ? 9.068   3.743   -2.461  0.5  38.004 ? 1244 ARG A CA     1 ? 
ATOM   3745 C C      A ARG A 1 236 ? 5.323   0.911   -4.336  0.5  24.641 ? 1244 ARG A C      1 ? 
ATOM   3746 C C      B ARG A 1 236 ? 7.864   3.839   -3.4    0.5  35.626 ? 1244 ARG A C      1 ? 
ATOM   3747 O O      A ARG A 1 236 ? 5.023   1.724   -5.21   0.5  24.386 ? 1244 ARG A O      1 ? 
ATOM   3748 O O      B ARG A 1 236 ? 7.697   4.848   -4.081  0.5  34.695 ? 1244 ARG A O      1 ? 
ATOM   3749 C CB     A ARG A 1 236 ? 7.797   0.949   -4.366  0.5  25.464 ? 1244 ARG A CB     1 ? 
ATOM   3750 C CB     B ARG A 1 236 ? 10.349  3.672   -3.301  0.5  40.603 ? 1244 ARG A CB     1 ? 
ATOM   3751 C CG     A ARG A 1 236 ? 7.723   -0.368  -5.12   0.5  27.693 ? 1244 ARG A CG     1 ? 
ATOM   3752 C CG     B ARG A 1 236 ? 11.64   3.863   -2.52   0.5  42.892 ? 1244 ARG A CG     1 ? 
ATOM   3753 C CD     A ARG A 1 236 ? 9.092   -0.805  -5.608  0.5  31.907 ? 1244 ARG A CD     1 ? 
ATOM   3754 C CD     B ARG A 1 236 ? 12.821  3.554   -3.422  0.5  46.005 ? 1244 ARG A CD     1 ? 
ATOM   3755 N NE     A ARG A 1 236 ? 9.005   -1.095  -7.041  0.5  32.518 ? 1244 ARG A NE     1 ? 
ATOM   3756 N NE     B ARG A 1 236 ? 14.103  3.537   -2.711  0.5  50.252 ? 1244 ARG A NE     1 ? 
ATOM   3757 C CZ     A ARG A 1 236 ? 8.064   -1.815  -7.614  0.5  33.413 ? 1244 ARG A CZ     1 ? 
ATOM   3758 C CZ     B ARG A 1 236 ? 15.016  4.494   -2.838  0.5  56.166 ? 1244 ARG A CZ     1 ? 
ATOM   3759 N NH1    A ARG A 1 236 ? 7.456   -2.794  -6.98   0.5  37.22  ? 1244 ARG A NH1    1 ? 
ATOM   3760 N NH1    B ARG A 1 236 ? 14.773  5.526   -3.626  0.5  56.309 ? 1244 ARG A NH1    1 ? 
ATOM   3761 N NH2    A ARG A 1 236 ? 7.746   -1.542  -8.856  0.5  34.843 ? 1244 ARG A NH2    1 ? 
ATOM   3762 N NH2    B ARG A 1 236 ? 16.162  4.425   -2.185  0.5  60.718 ? 1244 ARG A NH2    1 ? 
ATOM   3763 H H      A ARG A 1 236 ? 7.522   -0.293  -2.244  0.5  20.609 ? 1244 ARG A H      1 ? 
ATOM   3764 H H      B ARG A 1 236 ? 9.497   1.731   -1.804  0.5  30.703 ? 1244 ARG A H      1 ? 
ATOM   3765 H HA     A ARG A 1 236 ? 6.55    2.215   -3.134  0.5  23.026 ? 1244 ARG A HA     1 c 
ATOM   3766 H HA     B ARG A 1 236 ? 9.099   4.638   -1.836  0.5  37.511 ? 1244 ARG A HA     1 c 
ATOM   3767 H HB2    A ARG A 1 236 ? 7.877   1.767   -5.085  0.5  25.445 ? 1244 ARG A HB2    1 c 
ATOM   3768 H HB2    B ARG A 1 236 ? 10.383  2.7     -3.798  0.5  40.507 ? 1244 ARG A HB2    1 c 
ATOM   3769 H HB3    A ARG A 1 236 ? 8.695   0.956   -3.745  0.5  25.446 ? 1244 ARG A HB3    1 c 
ATOM   3770 H HB3    B ARG A 1 236 ? 10.295  4.437   -4.078  0.5  40.507 ? 1244 ARG A HB3    1 c 
ATOM   3771 H HG2    A ARG A 1 236 ? 7.314   -1.137  -4.463  0.5  28.095 ? 1244 ARG A HG2    1 c 
ATOM   3772 H HG2    B ARG A 1 236 ? 11.71   4.895   -2.169  0.5  43.039 ? 1244 ARG A HG2    1 c 
ATOM   3773 H HG3    A ARG A 1 236 ? 7.055   -0.259  -5.977  0.5  28.058 ? 1244 ARG A HG3    1 c 
ATOM   3774 H HG3    B ARG A 1 236 ? 11.655  3.193   -1.658  0.5  43.039 ? 1244 ARG A HG3    1 c 
ATOM   3775 H HD2    A ARG A 1 236 ? 9.819   -0.008  -5.441  0.5  31.088 ? 1244 ARG A HD2    1 c 
ATOM   3776 H HD2    B ARG A 1 236 ? 12.661  2.582   -3.893  0.5  46.224 ? 1244 ARG A HD2    1 c 
ATOM   3777 H HD3    A ARG A 1 236 ? 9.424   -1.695  -5.073  0.5  31.119 ? 1244 ARG A HD3    1 c 
ATOM   3778 H HD3    B ARG A 1 236 ? 12.863  4.305   -4.214  0.5  46.223 ? 1244 ARG A HD3    1 c 
ATOM   3779 H HE     A ARG A 1 236 ? 9.724   -0.711  -7.644  0.5  32.39  ? 1244 ARG A HE     1 ? 
ATOM   3780 H HE     B ARG A 1 236 ? 14.306  2.75    -2.112  0.5  46.696 ? 1244 ARG A HE     1 ? 
ATOM   3781 H HH11   A ARG A 1 236 ? 7.756   -3.069  -6.057  0.5  36.034 ? 1244 ARG A HH11   1 ? 
ATOM   3782 H HH11   B ARG A 1 236 ? 13.908  5.55    -4.156  0.5  56.018 ? 1244 ARG A HH11   1 ? 
ATOM   3783 H HH12   A ARG A 1 236 ? 6.69    -3.276  -7.434  0.5  36.192 ? 1244 ARG A HH12   1 ? 
ATOM   3784 H HH12   B ARG A 1 236 ? 15.452  6.276   -3.704  0.5  57.445 ? 1244 ARG A HH12   1 ? 
ATOM   3785 H HH21   A ARG A 1 236 ? 8.065   -0.652  -9.23   0.5  34.057 ? 1244 ARG A HH21   1 ? 
ATOM   3786 H HH21   B ARG A 1 236 ? 16.348  3.642   -1.572  0.5  59.302 ? 1244 ARG A HH21   1 ? 
ATOM   3787 H HH22   A ARG A 1 236 ? 7.129   -2.149  -9.382  0.5  34.605 ? 1244 ARG A HH22   1 ? 
ATOM   3788 H HH22   B ARG A 1 236 ? 16.85   5.163   -2.304  0.5  59.905 ? 1244 ARG A HH22   1 ? 
ATOM   3789 N N      A SER A 1 237 ? 4.589   -0.196  -4.128  0.5  23.972 ? 1245 SER A N      1 ? 
ATOM   3790 N N      B SER A 1 237 ? 7.045   2.778   -3.452  0.5  33.768 ? 1245 SER A N      1 ? 
ATOM   3791 C CA     A SER A 1 237 ? 3.314   -0.355  -4.808  0.5  25.195 ? 1245 SER A CA     1 ? 
ATOM   3792 C CA     B SER A 1 237 ? 5.834   2.785   -4.259  0.5  33.084 ? 1245 SER A CA     1 ? 
ATOM   3793 C C      A SER A 1 237 ? 2.169   0.048   -3.874  0.5  25.167 ? 1245 SER A C      1 ? 
ATOM   3794 C C      B SER A 1 237 ? 4.647   3.276   -3.429  0.5  33.549 ? 1245 SER A C      1 ? 
ATOM   3795 O O      A SER A 1 237 ? 1.037   0.228   -4.318  0.5  27.083 ? 1245 SER A O      1 ? 
ATOM   3796 O O      B SER A 1 237 ? 3.525   3.315   -3.934  0.5  32.431 ? 1245 SER A O      1 ? 
ATOM   3797 C CB     A SER A 1 237 ? 3.152   -1.766  -5.327  0.5  25.067 ? 1245 SER A CB     1 ? 
ATOM   3798 C CB     B SER A 1 237 ? 5.541   1.414   -4.845  0.5  33.307 ? 1245 SER A CB     1 ? 
ATOM   3799 O OG     A SER A 1 237 ? 4.318   -2.146  -6.047  0.5  24.963 ? 1245 SER A OG     1 ? 
ATOM   3800 O OG     B SER A 1 237 ? 6.706   0.777   -5.352  0.5  31.885 ? 1245 SER A OG     1 ? 
ATOM   3801 H H      A SER A 1 237 ? 4.908   -0.954  -3.501  0.5  23.577 ? 1245 SER A H      1 ? 
ATOM   3802 H H      B SER A 1 237 ? 7.27    1.929   -2.902  0.5  33.938 ? 1245 SER A H      1 ? 
ATOM   3803 H HA     A SER A 1 237 ? 3.304   0.325   -5.663  0.5  24.932 ? 1245 SER A HA     1 c 
ATOM   3804 H HA     B SER A 1 237 ? 5.984   3.485   -5.083  0.5  33.334 ? 1245 SER A HA     1 c 
ATOM   3805 H HB2    A SER A 1 237 ? 2.997   -2.449  -4.49   0.5  25.07  ? 1245 SER A HB2    1 c 
ATOM   3806 H HB2    B SER A 1 237 ? 5.095   0.784   -4.073  0.5  32.924 ? 1245 SER A HB2    1 c 
ATOM   3807 H HB3    A SER A 1 237 ? 2.281   -1.817  -5.984  0.5  25.07  ? 1245 SER A HB3    1 c 
ATOM   3808 H HB3    B SER A 1 237 ? 4.812   1.521   -5.651  0.5  32.924 ? 1245 SER A HB3    1 c 
ATOM   3809 H HG     A SER A 1 237 ? 4.213   -3.067  -6.338  0.5  25.141 ? 1245 SER A HG     1 ? 
ATOM   3810 H HG     B SER A 1 237 ? 6.418   0.065   -5.954  0.5  31.469 ? 1245 SER A HG     1 ? 
ATOM   3811 N N      A GLY A 1 238 ? 2.479   0.198   -2.581  0.5  24.299 ? 1246 GLY A N      1 ? 
ATOM   3812 N N      B GLY A 1 238 ? 4.915   3.694   -2.179  0.5  30.296 ? 1246 GLY A N      1 ? 
ATOM   3813 C CA     A GLY A 1 238 ? 1.498   0.578   -1.581  0.5  23.732 ? 1246 GLY A CA     1 ? 
ATOM   3814 C CA     B GLY A 1 238 ? 3.886   4.04    -1.215  0.5  27.101 ? 1246 GLY A CA     1 ? 
ATOM   3815 C C      A GLY A 1 238 ? 0.725   -0.622  -1.037  0.5  23.146 ? 1246 GLY A C      1 ? 
ATOM   3816 C C      B GLY A 1 238 ? 3.214   2.844   -0.548  0.5  24.938 ? 1246 GLY A C      1 ? 
ATOM   3817 O O      A GLY A 1 238 ? -0.443  -0.491  -0.683  0.5  24.066 ? 1246 GLY A O      1 ? 
ATOM   3818 O O      B GLY A 1 238 ? 2.293   3.037   0.24    0.5  26.441 ? 1246 GLY A O      1 ? 
ATOM   3819 H H      A GLY A 1 238 ? 3.46    0.053   -2.28   0.5  24.41  ? 1246 GLY A H      1 ? 
ATOM   3820 H H      B GLY A 1 238 ? 5.899   3.89    -1.925  0.5  31.066 ? 1246 GLY A H      1 ? 
ATOM   3821 H HA2    A GLY A 1 238 ? 2.014   1.074   -0.756  0.5  23.735 ? 1246 GLY A HA2    1 c 
ATOM   3822 H HA2    B GLY A 1 238 ? 4.332   4.671   -0.443  0.5  27.305 ? 1246 GLY A HA2    1 c 
ATOM   3823 H HA3    A GLY A 1 238 ? 0.799   1.298   -2.013  0.5  23.743 ? 1246 GLY A HA3    1 c 
ATOM   3824 H HA3    B GLY A 1 238 ? 3.124   4.635   -1.723  0.5  27.286 ? 1246 GLY A HA3    1 c 
ATOM   3825 N N      A GLY A 1 239 ? 1.376   -1.791  -1.024  0.5  22.929 ? 1247 GLY A N      1 ? 
ATOM   3826 N N      B GLY A 1 239 ? 3.649   1.613   -0.853  0.5  25.016 ? 1247 GLY A N      1 ? 
ATOM   3827 C CA     A GLY A 1 239 ? 1.007   -2.875  -0.118  0.5  20.723 ? 1247 GLY A CA     1 ? 
ATOM   3828 C CA     B GLY A 1 239 ? 2.993   0.41    -0.336  0.5  22.707 ? 1247 GLY A CA     1 ? 
ATOM   3829 C C      A GLY A 1 239 ? 1.762   -2.748  1.208   0.5  19.273 ? 1247 GLY A C      1 ? 
ATOM   3830 C C      B GLY A 1 239 ? 3.625   -0.104  0.962   0.5  22.384 ? 1247 GLY A C      1 ? 
ATOM   3831 O O      A GLY A 1 239 ? 2.574   -1.851  1.404   0.5  17.712 ? 1247 GLY A O      1 ? 
ATOM   3832 O O      B GLY A 1 239 ? 4.724   0.318   1.313   0.5  21.4   ? 1247 GLY A O      1 ? 
ATOM   3833 H H      A GLY A 1 239 ? 2.176   -1.932  -1.671  0.5  21.563 ? 1247 GLY A H      1 ? 
ATOM   3834 H H      B GLY A 1 239 ? 4.457   1.511   -1.489  0.5  24.282 ? 1247 GLY A H      1 ? 
ATOM   3835 H HA2    A GLY A 1 239 ? -0.069  -2.842  0.066   0.5  20.865 ? 1247 GLY A HA2    1 c 
ATOM   3836 H HA2    B GLY A 1 239 ? 1.94    0.635   -0.157  0.5  23.134 ? 1247 GLY A HA2    1 c 
ATOM   3837 H HA3    A GLY A 1 239 ? 1.242   -3.834  -0.586  0.5  20.807 ? 1247 GLY A HA3    1 c 
ATOM   3838 H HA3    B GLY A 1 239 ? 3.038   -0.374  -1.095  0.5  23.101 ? 1247 GLY A HA3    1 c 
ATOM   3839 N N      A LYS A 1 240 ? 1.422   -3.616  2.152   0.5  19.517 ? 1248 LYS A N      1 ? 
ATOM   3840 N N      B LYS A 1 240 ? 2.899   -0.97   1.7     0.5  22.596 ? 1248 LYS A N      1 ? 
ATOM   3841 C CA     A LYS A 1 240 ? 2.156   -3.735  3.41    0.5  20.7   ? 1248 LYS A CA     1 ? 
ATOM   3842 C CA     B LYS A 1 240 ? 3.381   -1.494  2.971   0.5  23.329 ? 1248 LYS A CA     1 ? 
ATOM   3843 C C      A LYS A 1 240 ? 3.616   -4.088  3.094   0.5  18.497 ? 1248 LYS A C      1 ? 
ATOM   3844 C C      B LYS A 1 240 ? 4.77    -2.093  2.766   0.5  21.742 ? 1248 LYS A C      1 ? 
ATOM   3845 O O      A LYS A 1 240 ? 3.855   -4.921  2.218   0.5  18.238 ? 1248 LYS A O      1 ? 
ATOM   3846 O O      B LYS A 1 240 ? 5.019   -2.742  1.758   0.5  22.827 ? 1248 LYS A O      1 ? 
ATOM   3847 C CB     A LYS A 1 240 ? 1.528   -4.842  4.275   0.5  22.143 ? 1248 LYS A CB     1 ? 
ATOM   3848 C CB     B LYS A 1 240 ? 2.499   -2.571  3.626   0.5  25.678 ? 1248 LYS A CB     1 ? 
ATOM   3849 C CG     A LYS A 1 240 ? 0.213   -4.548  5.004   0.5  24.929 ? 1248 LYS A CG     1 ? 
ATOM   3850 C CG     B LYS A 1 240 ? 1.207   -2.078  4.276   0.5  27.183 ? 1248 LYS A CG     1 ? 
ATOM   3851 C CD     A LYS A 1 240 ? -0.72   -5.757  5.077   0.5  29.295 ? 1248 LYS A CD     1 ? 
ATOM   3852 C CD     B LYS A 1 240 ? 0.737   -2.846  5.509   0.5  30.039 ? 1248 LYS A CD     1 ? 
ATOM   3853 C CE     A LYS A 1 240 ? -1.826  -5.653  6.076   0.5  32.962 ? 1248 LYS A CE     1 ? 
ATOM   3854 C CE     B LYS A 1 240 ? 0.018   -4.148  5.253   0.5  28.858 ? 1248 LYS A CE     1 ? 
ATOM   3855 N NZ     A LYS A 1 240 ? -1.276  -5.979  7.394   0.5  35.323 ? 1248 LYS A NZ     1 ? 
ATOM   3856 N NZ     B LYS A 1 240 ? -0.404  -4.767  6.517   0.5  29.735 ? 1248 LYS A NZ     1 ? 
ATOM   3857 H H      A LYS A 1 240 ? 0.615   -4.238  1.976   0.5  19.405 ? 1248 LYS A H      1 ? 
ATOM   3858 H H      B LYS A 1 240 ? 1.97    -1.271  1.356   0.5  22.715 ? 1248 LYS A H      1 ? 
ATOM   3859 H HA     A LYS A 1 240 ? 2.118   -2.777  3.934   0.5  20.307 ? 1248 LYS A HA     1 c 
ATOM   3860 H HA     B LYS A 1 240 ? 3.468   -0.658  3.668   0.5  23.291 ? 1248 LYS A HA     1 c 
ATOM   3861 H HB2    A LYS A 1 240 ? 1.365   -5.711  3.635   0.5  22.436 ? 1248 LYS A HB2    1 c 
ATOM   3862 H HB2    B LYS A 1 240 ? 2.236   -3.31   2.865   0.5  25.465 ? 1248 LYS A HB2    1 c 
ATOM   3863 H HB3    A LYS A 1 240 ? 2.265   -5.133  5.026   0.5  22.403 ? 1248 LYS A HB3    1 c 
ATOM   3864 H HB3    B LYS A 1 240 ? 3.09    -3.083  4.388   0.5  25.465 ? 1248 LYS A HB3    1 c 
ATOM   3865 H HG2    A LYS A 1 240 ? 0.442   -4.212  6.018   0.5  25.162 ? 1248 LYS A HG2    1 c 
ATOM   3866 H HG2    B LYS A 1 240 ? 1.346   -1.031  4.553   0.5  27.437 ? 1248 LYS A HG2    1 c 
ATOM   3867 H HG3    A LYS A 1 240 ? -0.298  -3.732  4.488   0.5  25.162 ? 1248 LYS A HG3    1 c 
ATOM   3868 H HG3    B LYS A 1 240 ? 0.416   -2.111  3.525   0.5  27.438 ? 1248 LYS A HG3    1 c 
ATOM   3869 H HD2    A LYS A 1 240 ? -1.163  -5.903  4.092   0.5  29.246 ? 1248 LYS A HD2    1 c 
ATOM   3870 H HD2    B LYS A 1 240 ? 1.607   -3.048  6.136   0.5  29.151 ? 1248 LYS A HD2    1 c 
ATOM   3871 H HD3    A LYS A 1 240 ? -0.124  -6.643  5.303   0.5  29.079 ? 1248 LYS A HD3    1 c 
ATOM   3872 H HD3    B LYS A 1 240 ? 0.076   -2.194  6.083   0.5  29.235 ? 1248 LYS A HD3    1 c 
ATOM   3873 H HE2    A LYS A 1 240 ? -2.233  -4.64   6.089   0.5  32.63  ? 1248 LYS A HE2    1 c 
ATOM   3874 H HE2    B LYS A 1 240 ? -0.862  -3.967  4.631   0.5  29.307 ? 1248 LYS A HE2    1 c 
ATOM   3875 H HE3    A LYS A 1 240 ? -2.627  -6.354  5.831   0.5  32.63  ? 1248 LYS A HE3    1 c 
ATOM   3876 H HE3    B LYS A 1 240 ? 0.679   -4.835  4.721   0.5  29.307 ? 1248 LYS A HE3    1 c 
ATOM   3877 H HZ1    A LYS A 1 240 ? -2.017  -6.028  8.093   0.5  34.995 ? 1248 LYS A HZ1    1 ? 
ATOM   3878 H HZ1    B LYS A 1 240 ? 0.395   -5.192  6.991   0.5  28.458 ? 1248 LYS A HZ1    1 ? 
ATOM   3879 H HZ2    A LYS A 1 240 ? -0.81   -6.883  7.318   0.5  34.629 ? 1248 LYS A HZ2    1 ? 
ATOM   3880 H HZ2    B LYS A 1 240 ? -0.808  -4.055  7.124   0.5  29.076 ? 1248 LYS A HZ2    1 ? 
ATOM   3881 H HZ3    A LYS A 1 240 ? -0.595  -5.274  7.672   0.5  34.062 ? 1248 LYS A HZ3    1 ? 
ATOM   3882 H HZ3    B LYS A 1 240 ? -1.102  -5.486  6.342   0.5  28.205 ? 1248 LYS A HZ3    1 ? 
ATOM   3883 N N      A MET A 1 241 ? 4.569   -3.445  3.793   0.5  15.814 ? 1249 MET A N      1 ? 
ATOM   3884 N N      B MET A 1 241 ? 5.654   -1.884  3.751   0.5  22.286 ? 1249 MET A N      1 ? 
ATOM   3885 C CA     A MET A 1 241 ? 5.995   -3.699  3.64    0.5  16.2   ? 1249 MET A CA     1 ? 
ATOM   3886 C CA     B MET A 1 241 ? 7.043   -2.305  3.647   0.5  20.147 ? 1249 MET A CA     1 ? 
ATOM   3887 C C      A MET A 1 241 ? 6.389   -5.048  4.235   0.5  15.578 ? 1249 MET A C      1 ? 
ATOM   3888 C C      B MET A 1 241 ? 7.204   -3.717  4.203   0.5  19.443 ? 1249 MET A C      1 ? 
ATOM   3889 O O      A MET A 1 241 ? 6.387   -5.252  5.454   0.5  17.129 ? 1249 MET A O      1 ? 
ATOM   3890 O O      B MET A 1 241 ? 7.205   -3.909  5.416   0.5  20.038 ? 1249 MET A O      1 ? 
ATOM   3891 C CB     A MET A 1 241 ? 6.868   -2.65   4.341   0.5  15.614 ? 1249 MET A CB     1 ? 
ATOM   3892 C CB     B MET A 1 241 ? 7.963   -1.349  4.418   0.5  17.899 ? 1249 MET A CB     1 ? 
ATOM   3893 C CG     A MET A 1 241 ? 8.302   -2.537  3.807   0.5  14.547 ? 1249 MET A CG     1 ? 
ATOM   3894 C CG     B MET A 1 241 ? 9.431   -1.658  4.229   0.5  16.551 ? 1249 MET A CG     1 ? 
ATOM   3895 S SD     A MET A 1 241 ? 8.376   -1.603  2.265   0.5  15.085 ? 1249 MET A SD     1 ? 
ATOM   3896 S SD     B MET A 1 241 ? 10.466  -0.181  4.117   0.5  15.682 ? 1249 MET A SD     1 ? 
ATOM   3897 C CE     A MET A 1 241 ? 9.961   -0.761  2.387   0.5  15.908 ? 1249 MET A CE     1 ? 
ATOM   3898 C CE     B MET A 1 241 ? 11.191  0.066   5.745   0.5  14.726 ? 1249 MET A CE     1 ? 
ATOM   3899 H H      A MET A 1 241 ? 4.276   -2.724  4.476   0.5  16.655 ? 1249 MET A H      1 ? 
ATOM   3900 H H      B MET A 1 241 ? 5.343   -1.417  4.625   0.5  22.33  ? 1249 MET A H      1 ? 
ATOM   3901 H HA     A MET A 1 241 ? 6.227   -3.709  2.573   0.5  15.912 ? 1249 MET A HA     1 c 
ATOM   3902 H HA     B MET A 1 241 ? 7.323   -2.31   2.592   0.5  19.988 ? 1249 MET A HA     1 c 
ATOM   3903 H HB2    A MET A 1 241 ? 6.381   -1.677  4.246   0.5  15.5   ? 1249 MET A HB2    1 c 
ATOM   3904 H HB2    B MET A 1 241 ? 7.768   -0.328  4.085   0.5  18.05  ? 1249 MET A HB2    1 c 
ATOM   3905 H HB3    A MET A 1 241 ? 6.91    -2.893  5.405   0.5  15.5   ? 1249 MET A HB3    1 c 
ATOM   3906 H HB3    B MET A 1 241 ? 7.72    -1.407  5.481   0.5  18.05  ? 1249 MET A HB3    1 c 
ATOM   3907 H HG2    A MET A 1 241 ? 8.929   -2.042  4.551   0.5  14.88  ? 1249 MET A HG2    1 c 
ATOM   3908 H HG2    B MET A 1 241 ? 9.78    -2.265  5.066   0.5  16.712 ? 1249 MET A HG2    1 c 
ATOM   3909 H HG3    A MET A 1 241 ? 8.706   -3.537  3.635   0.5  14.88  ? 1249 MET A HG3    1 c 
ATOM   3910 H HG3    B MET A 1 241 ? 9.56    -2.244  3.317   0.5  16.691 ? 1249 MET A HG3    1 c 
ATOM   3911 H HE1    A MET A 1 241 ? 10.123  -0.159  1.491   0.5  15.701 ? 1249 MET A HE1    1 c 
ATOM   3912 H HE1    B MET A 1 241 ? 11.941  0.858   5.692   0.5  15.009 ? 1249 MET A HE1    1 c 
ATOM   3913 H HE2    A MET A 1 241 ? 9.961   -0.114  3.266   0.5  15.701 ? 1249 MET A HE2    1 c 
ATOM   3914 H HE2    B MET A 1 241 ? 10.409  0.352   6.451   0.5  15.009 ? 1249 MET A HE2    1 c 
ATOM   3915 H HE3    A MET A 1 241 ? 10.759  -1.501  2.478   0.5  15.679 ? 1249 MET A HE3    1 c 
ATOM   3916 H HE3    B MET A 1 241 ? 11.662  -0.86   6.078   0.5  15.191 ? 1249 MET A HE3    1 c 
ATOM   3917 N N      A TYR A 1 242 ? 6.776   -5.94   3.335   0.5  15.178 ? 1250 TYR A N      1 ? 
ATOM   3918 N N      B TYR A 1 242 ? 7.381   -4.686  3.296   0.5  19.613 ? 1250 TYR A N      1 ? 
ATOM   3919 C CA     A TYR A 1 242 ? 7.204   -7.292  3.672   0.5  16.008 ? 1250 TYR A CA     1 ? 
ATOM   3920 C CA     B TYR A 1 242 ? 7.59    -6.064  3.683   0.5  21.171 ? 1250 TYR A CA     1 ? 
ATOM   3921 C C      A TYR A 1 242 ? 8.691   -7.447  3.369   0.5  15.035 ? 1250 TYR A C      1 ? 
ATOM   3922 C C      B TYR A 1 242 ? 9.066   -6.368  3.432   0.5  18.846 ? 1250 TYR A C      1 ? 
ATOM   3923 O O      A TYR A 1 242 ? 9.291   -6.604  2.708   0.5  15.247 ? 1250 TYR A O      1 ? 
ATOM   3924 O O      B TYR A 1 242 ? 9.762   -5.594  2.773   0.5  16.814 ? 1250 TYR A O      1 ? 
ATOM   3925 C CB     A TYR A 1 242 ? 6.325   -8.292  2.915   0.5  16.586 ? 1250 TYR A CB     1 ? 
ATOM   3926 C CB     B TYR A 1 242 ? 6.674   -7.05   2.951   0.5  24.98  ? 1250 TYR A CB     1 ? 
ATOM   3927 C CG     A TYR A 1 242 ? 4.906   -8.351  3.466   0.5  18.067 ? 1250 TYR A CG     1 ? 
ATOM   3928 C CG     B TYR A 1 242 ? 5.202   -7.028  3.347   0.5  27.061 ? 1250 TYR A CG     1 ? 
ATOM   3929 C CD1    A TYR A 1 242 ? 4.708   -8.583  4.817   0.5  17.771 ? 1250 TYR A CD1    1 ? 
ATOM   3930 C CD1    B TYR A 1 242 ? 4.767   -7.605  4.533   0.5  27.267 ? 1250 TYR A CD1    1 ? 
ATOM   3931 C CD2    A TYR A 1 242 ? 3.779   -8.168  2.663   0.5  17.601 ? 1250 TYR A CD2    1 ? 
ATOM   3932 C CD2    B TYR A 1 242 ? 4.236   -6.498  2.498   0.5  30.042 ? 1250 TYR A CD2    1 ? 
ATOM   3933 C CE1    A TYR A 1 242 ? 3.439   -8.659  5.36    0.5  17.959 ? 1250 TYR A CE1    1 ? 
ATOM   3934 C CE1    B TYR A 1 242 ? 3.428   -7.61   4.886   0.05 29.427 ? 1250 TYR A CE1    1 ? 
ATOM   3935 C CE2    A TYR A 1 242 ? 2.496   -8.229  3.201   0.5  17.66  ? 1250 TYR A CE2    1 ? 
ATOM   3936 C CE2    B TYR A 1 242 ? 2.889   -6.494  2.838   0.5  29.29  ? 1250 TYR A CE2    1 ? 
ATOM   3937 C CZ     A TYR A 1 242 ? 2.328   -8.474  4.558   0.5  16.974 ? 1250 TYR A CZ     1 ? 
ATOM   3938 C CZ     B TYR A 1 242 ? 2.487   -7.049  4.041   0.5  32.151 ? 1250 TYR A CZ     1 ? 
ATOM   3939 O OH     A TYR A 1 242 ? 1.128   -8.561  5.204   0.05 16.408 ? 1250 TYR A OH     1 ? 
ATOM   3940 O OH     B TYR A 1 242 ? 1.162   -7.059  4.395   0.5  33.771 ? 1250 TYR A OH     1 ? 
ATOM   3941 H H      A TYR A 1 242 ? 6.754   -5.658  2.34    0.5  15.408 ? 1250 TYR A H      1 ? 
ATOM   3942 H H      B TYR A 1 242 ? 7.487   -4.432  2.297   0.5  18.333 ? 1250 TYR A H      1 ? 
ATOM   3943 H HA     A TYR A 1 242 ? 7.051   -7.441  4.743   0.5  15.811 ? 1250 TYR A HA     1 c 
ATOM   3944 H HA     B TYR A 1 242 ? 7.398   -6.149  4.755   0.5  21.048 ? 1250 TYR A HA     1 c 
ATOM   3945 H HB2    A TYR A 1 242 ? 6.288   -8.002  1.863   0.5  16.768 ? 1250 TYR A HB2    1 c 
ATOM   3946 H HB2    B TYR A 1 242 ? 6.747   -6.849  1.88    0.5  24.516 ? 1250 TYR A HB2    1 c 
ATOM   3947 H HB3    A TYR A 1 242 ? 6.778   -9.282  2.985   0.5  16.768 ? 1250 TYR A HB3    1 c 
ATOM   3948 H HB3    B TYR A 1 242 ? 7.062   -8.058  3.115   0.5  24.516 ? 1250 TYR A HB3    1 c 
ATOM   3949 H HD1    A TYR A 1 242 ? 5.568   -8.733  5.461   0.5  17.915 ? 1250 TYR A HD1    1 c 
ATOM   3950 H HD1    B TYR A 1 242 ? 5.495   -8.042  5.21    0.5  27.727 ? 1250 TYR A HD1    1 c 
ATOM   3951 H HD2    A TYR A 1 242 ? 3.904   -7.978  1.602   0.5  17.701 ? 1250 TYR A HD2    1 c 
ATOM   3952 H HD2    B TYR A 1 242 ? 4.549   -6.052  1.561   0.5  29.311 ? 1250 TYR A HD2    1 c 
ATOM   3953 H HE1    A TYR A 1 242 ? 3.314   -8.845  6.421   0.5  17.688 ? 1250 TYR A HE1    1 c 
ATOM   3954 H HE1    B TYR A 1 242 ? 3.116   -8.047  5.829   0.5  29.502 ? 1250 TYR A HE1    1 c 
ATOM   3955 H HE2    A TYR A 1 242 ? 1.629   -8.089  2.564   0.5  17.494 ? 1250 TYR A HE2    1 c 
ATOM   3956 H HE2    B TYR A 1 242 ? 2.155   -6.052  2.174   0.5  30.149 ? 1250 TYR A HE2    1 c 
ATOM   3957 H HH     A TYR A 1 242 ? 0.387   -8.456  4.615   0.5  15.279 ? 1250 TYR A HH     1 ? 
ATOM   3958 H HH     B TYR A 1 242 ? 0.63    -6.567  3.749   0.5  33.397 ? 1250 TYR A HH     1 ? 
ATOM   3959 N N      A VAL A 1 243 ? 9.281   -8.546  3.857   0.5  16.363 ? 1251 VAL A N      1 ? 
ATOM   3960 N N      B VAL A 1 243 ? 9.534   -7.467  4.019   0.5  17.96  ? 1251 VAL A N      1 ? 
ATOM   3961 C CA     A VAL A 1 243 ? 10.718  -8.714  3.782   0.5  16.705 ? 1251 VAL A CA     1 ? 
ATOM   3962 C CA     B VAL A 1 243 ? 10.909  -7.901  3.86    0.5  17.834 ? 1251 VAL A CA     1 ? 
ATOM   3963 C C      A VAL A 1 243 ? 11.138  -8.839  2.317   0.5  16.738 ? 1251 VAL A C      1 ? 
ATOM   3964 C C      B VAL A 1 243 ? 11.297  -7.98   2.379   0.5  17.492 ? 1251 VAL A C      1 ? 
ATOM   3965 O O      A VAL A 1 243 ? 12.273  -8.524  1.986   0.5  18.111 ? 1251 VAL A O      1 ? 
ATOM   3966 O O      B VAL A 1 243 ? 12.395  -7.555  2.026   0.5  17.833 ? 1251 VAL A O      1 ? 
ATOM   3967 C CB     A VAL A 1 243 ? 11.234  -9.882  4.645   0.5  16     ? 1251 VAL A CB     1 ? 
ATOM   3968 C CB     B VAL A 1 243 ? 11.134  -9.245  4.576   0.5  17.587 ? 1251 VAL A CB     1 ? 
ATOM   3969 C CG1    A VAL A 1 243 ? 10.819  -11.246 4.112   0.5  15.602 ? 1251 VAL A CG1    1 ? 
ATOM   3970 C CG1    B VAL A 1 243 ? 10.664  -10.416 3.731   0.5  17.699 ? 1251 VAL A CG1    1 ? 
ATOM   3971 C CG2    A VAL A 1 243 ? 12.752  -9.816  4.804   0.5  17.42  ? 1251 VAL A CG2    1 ? 
ATOM   3972 C CG2    B VAL A 1 243 ? 12.596  -9.4    4.982   0.5  18.816 ? 1251 VAL A CG2    1 ? 
ATOM   3973 H H      A VAL A 1 243 ? 8.71    -9.301  4.274   0.5  16.186 ? 1251 VAL A H      1 ? 
ATOM   3974 H H      B VAL A 1 243 ? 8.92    -7.999  4.663   0.5  17.443 ? 1251 VAL A H      1 ? 
ATOM   3975 H HA     A VAL A 1 243 ? 11.169  -7.799  4.172   0.5  16.519 ? 1251 VAL A HA     1 c 
ATOM   3976 H HA     B VAL A 1 243 ? 11.55   -7.156  4.336   0.5  17.753 ? 1251 VAL A HA     1 c 
ATOM   3977 H HB     A VAL A 1 243 ? 10.792  -9.766  5.637   0.5  16.298 ? 1251 VAL A HB     1 c 
ATOM   3978 H HB     B VAL A 1 243 ? 10.534  -9.228  5.488   0.5  17.897 ? 1251 VAL A HB     1 c 
ATOM   3979 H HG11   A VAL A 1 243 ? 11.21   -12.028 4.765   0.5  15.718 ? 1251 VAL A HG11   1 c 
ATOM   3980 H HG11   B VAL A 1 243 ? 10.842  -11.349 4.27    0.5  17.669 ? 1251 VAL A HG11   1 c 
ATOM   3981 H HG12   A VAL A 1 243 ? 9.729   -11.31  4.081   0.5  15.718 ? 1251 VAL A HG12   1 c 
ATOM   3982 H HG12   B VAL A 1 243 ? 9.597   -10.313 3.525   0.5  17.669 ? 1251 VAL A HG12   1 c 
ATOM   3983 H HG13   A VAL A 1 243 ? 11.218  -11.381 3.104   0.5  15.737 ? 1251 VAL A HG13   1 c 
ATOM   3984 H HG13   B VAL A 1 243 ? 11.216  -10.431 2.788   0.5  17.673 ? 1251 VAL A HG13   1 c 
ATOM   3985 H HG21   A VAL A 1 243 ? 13.092  -10.654 5.417   0.5  17.012 ? 1251 VAL A HG21   1 c 
ATOM   3986 H HG21   B VAL A 1 243 ? 12.735  -10.36  5.485   0.5  18.463 ? 1251 VAL A HG21   1 c 
ATOM   3987 H HG22   A VAL A 1 243 ? 13.225  -9.87   3.821   0.5  17.012 ? 1251 VAL A HG22   1 c 
ATOM   3988 H HG22   B VAL A 1 243 ? 13.228  -9.362  4.092   0.5  18.463 ? 1251 VAL A HG22   1 c 
ATOM   3989 H HG23   A VAL A 1 243 ? 13.028  -8.878  5.289   0.5  17.006 ? 1251 VAL A HG23   1 c 
ATOM   3990 H HG23   B VAL A 1 243 ? 12.874  -8.591  5.66    0.5  18.449 ? 1251 VAL A HG23   1 c 
ATOM   3991 N N      A GLN A 1 244 ? 10.235  -9.286  1.433   0.5  17.714 ? 1252 GLN A N      1 ? 
ATOM   3992 N N      B GLN A 1 244 ? 10.43   -8.503  1.502   0.5  18.163 ? 1252 GLN A N      1 ? 
ATOM   3993 C CA     A GLN A 1 244 ? 10.551  -9.36   0.012   0.5  18.282 ? 1252 GLN A CA     1 ? 
ATOM   3994 C CA     B GLN A 1 244 ? 10.811  -8.656  0.105   0.5  19.496 ? 1252 GLN A CA     1 ? 
ATOM   3995 C C      A GLN A 1 244 ? 10.775  -7.965  -0.581  0.5  19.072 ? 1252 GLN A C      1 ? 
ATOM   3996 C C      B GLN A 1 244 ? 10.936  -7.286  -0.564  0.5  20.833 ? 1252 GLN A C      1 ? 
ATOM   3997 O O      A GLN A 1 244 ? 11.567  -7.811  -1.508  0.5  16.165 ? 1252 GLN A O      1 ? 
ATOM   3998 O O      B GLN A 1 244 ? 11.782  -7.108  -1.436  0.5  18.796 ? 1252 GLN A O      1 ? 
ATOM   3999 C CB     A GLN A 1 244 ? 9.543   -10.169 -0.815  0.5  17.716 ? 1252 GLN A CB     1 ? 
ATOM   4000 C CB     B GLN A 1 244 ? 9.871   -9.526  -0.733  0.5  19.457 ? 1252 GLN A CB     1 ? 
ATOM   4001 C CG     A GLN A 1 244 ? 8.075   -9.776  -0.655  0.5  17.456 ? 1252 GLN A CG     1 ? 
ATOM   4002 C CG     B GLN A 1 244 ? 8.427   -9.043  -0.759  0.5  19.006 ? 1252 GLN A CG     1 ? 
ATOM   4003 C CD     A GLN A 1 244 ? 7.361   -10.51  0.462   0.5  17.768 ? 1252 GLN A CD     1 ? 
ATOM   4004 C CD     B GLN A 1 244 ? 7.629   -9.512  0.435   0.5  19.236 ? 1252 GLN A CD     1 ? 
ATOM   4005 O OE1    A GLN A 1 244 ? 7.981   -10.993 1.414   0.5  17.325 ? 1252 GLN A OE1    1 ? 
ATOM   4006 O OE1    B GLN A 1 244 ? 8.182   -9.908  1.466   0.5  19.979 ? 1252 GLN A OE1    1 ? 
ATOM   4007 N NE2    A GLN A 1 244 ? 6.039   -10.599 0.377   0.5  17.058 ? 1252 GLN A NE2    1 ? 
ATOM   4008 N NE2    B GLN A 1 244 ? 6.31    -9.492  0.3     0.5  19.18  ? 1252 GLN A NE2    1 ? 
ATOM   4009 H H      A GLN A 1 244 ? 9.346   -9.692  1.769   0.5  17.46  ? 1252 GLN A H      1 ? 
ATOM   4010 H H      B GLN A 1 244 ? 9.49    -8.809  1.806   0.5  18.344 ? 1252 GLN A H      1 ? 
ATOM   4011 H HA     A GLN A 1 244 ? 11.498  -9.895  -0.074  0.5  18.239 ? 1252 GLN A HA     1 c 
ATOM   4012 H HA     B GLN A 1 244 ? 11.795  -9.128  0.082   0.5  19.457 ? 1252 GLN A HA     1 c 
ATOM   4013 H HB2    A GLN A 1 244 ? 9.815   -10.081 -1.867  0.5  17.899 ? 1252 GLN A HB2    1 c 
ATOM   4014 H HB2    B GLN A 1 244 ? 10.25   -9.56   -1.757  0.5  19.366 ? 1252 GLN A HB2    1 c 
ATOM   4015 H HB3    A GLN A 1 244 ? 9.65    -11.216 -0.536  0.5  17.92  ? 1252 GLN A HB3    1 c 
ATOM   4016 H HB3    B GLN A 1 244 ? 9.896   -10.543 -0.338  0.5  19.366 ? 1252 GLN A HB3    1 c 
ATOM   4017 H HG2    A GLN A 1 244 ? 8.013   -8.704  -0.458  0.5  17.585 ? 1252 GLN A HG2    1 c 
ATOM   4018 H HG2    B GLN A 1 244 ? 8.412   -7.951  -0.787  0.5  19.16  ? 1252 GLN A HG2    1 c 
ATOM   4019 H HG3    A GLN A 1 244 ? 7.549   -9.969  -1.591  0.5  17.602 ? 1252 GLN A HG3    1 c 
ATOM   4020 H HG3    B GLN A 1 244 ? 7.942   -9.406  -1.666  0.5  19.185 ? 1252 GLN A HG3    1 c 
ATOM   4021 H HE21   A GLN A 1 244 ? 5.548   -10.268 -0.422  0.5  16.604 ? 1252 GLN A HE21   1 ? 
ATOM   4022 H HE21   B GLN A 1 244 ? 5.883   -9.147  -0.552  0.5  19.197 ? 1252 GLN A HE21   1 ? 
ATOM   4023 H HE22   A GLN A 1 244 ? 5.521   -11.039 1.121   0.5  17.237 ? 1252 GLN A HE22   1 ? 
ATOM   4024 H HE22   B GLN A 1 244 ? 5.744   -9.829  1.069   0.5  19.198 ? 1252 GLN A HE22   1 ? 
ATOM   4025 N N      A ASP A 1 245 ? 10.106  -6.945  -0.03   0.5  20.137 ? 1253 ASP A N      1 ? 
ATOM   4026 N N      B ASP A 1 245 ? 10.112  -6.324  -0.119  0.5  20.778 ? 1253 ASP A N      1 ? 
ATOM   4027 C CA     A ASP A 1 245 ? 10.181  -5.596  -0.575  0.5  21.397 ? 1253 ASP A CA     1 ? 
ATOM   4028 C CA     B ASP A 1 245 ? 10.083  -4.982  -0.681  0.5  22.457 ? 1253 ASP A CA     1 ? 
ATOM   4029 C C      A ASP A 1 245 ? 11.526  -4.926  -0.286  0.5  23.46  ? 1253 ASP A C      1 ? 
ATOM   4030 C C      B ASP A 1 245 ? 11.369  -4.232  -0.327  0.5  22.46  ? 1253 ASP A C      1 ? 
ATOM   4031 O O      A ASP A 1 245 ? 11.998  -4.126  -1.087  0.5  24.804 ? 1253 ASP A O      1 ? 
ATOM   4032 O O      B ASP A 1 245 ? 12.084  -3.827  -1.268  0.5  24.005 ? 1253 ASP A O      1 ? 
ATOM   4033 C CB     A ASP A 1 245 ? 8.989   -4.771  -0.115  0.5  22.493 ? 1253 ASP A CB     1 ? 
ATOM   4034 C CB     B ASP A 1 245 ? 8.895   -4.169  -0.181  0.5  24.204 ? 1253 ASP A CB     1 ? 
ATOM   4035 C CG     A ASP A 1 245 ? 7.656   -5.494  -0.215  0.5  21.676 ? 1253 ASP A CG     1 ? 
ATOM   4036 C CG     B ASP A 1 245 ? 7.529   -4.675  -0.616  0.5  25.894 ? 1253 ASP A CG     1 ? 
ATOM   4037 O OD1    A ASP A 1 245 ? 7.276   -5.886  -1.341  0.5  22.422 ? 1253 ASP A OD1    1 ? 
ATOM   4038 O OD1    B ASP A 1 245 ? 7.268   -4.707  -1.841  0.5  25.458 ? 1253 ASP A OD1    1 ? 
ATOM   4039 O OD2    A ASP A 1 245 ? 7.024   -5.687  0.839   0.5  24.26  ? 1253 ASP A OD2    1 ? 
ATOM   4040 O OD2    B ASP A 1 245 ? 6.745   -5.049  0.27    0.5  27.179 ? 1253 ASP A OD2    1 ? 
ATOM   4041 H H      A ASP A 1 245 ? 9.508   -7.122  0.797   0.5  20.788 ? 1253 ASP A H      1 ? 
ATOM   4042 H H      B ASP A 1 245 ? 9.485   -6.54   0.675   0.5  21.408 ? 1253 ASP A H      1 ? 
ATOM   4043 H HA     A ASP A 1 245 ? 10.082  -5.677  -1.66   0.5  21.698 ? 1253 ASP A HA     1 c 
ATOM   4044 H HA     B ASP A 1 245 ? 10.012  -5.065  -1.768  0.5  22.428 ? 1253 ASP A HA     1 c 
ATOM   4045 H HB2    A ASP A 1 245 ? 9.144   -4.476  0.925   0.5  22.069 ? 1253 ASP A HB2    1 c 
ATOM   4046 H HB2    B ASP A 1 245 ? 8.918   -4.154  0.911   0.5  24.168 ? 1253 ASP A HB2    1 c 
ATOM   4047 H HB3    A ASP A 1 245 ? 8.934   -3.863  -0.72   0.5  22.069 ? 1253 ASP A HB3    1 c 
ATOM   4048 H HB3    B ASP A 1 245 ? 9.003   -3.141  -0.532  0.5  24.168 ? 1253 ASP A HB3    1 c 
ATOM   4049 N N      A LYS A 1 246 ? 12.136  -5.234  0.86    1    26.052 ? 1254 LYS A N      1 ? 
ATOM   4050 C CA     A LYS A 1 246 ? 13.433  -4.697  1.231   1    24.259 ? 1254 LYS A CA     1 ? 
ATOM   4051 C C      A LYS A 1 246 ? 14.531  -5.333  0.364   1    22.112 ? 1254 LYS A C      1 ? 
ATOM   4052 O O      A LYS A 1 246 ? 15.487  -4.636  0.009   1    24.42  ? 1254 LYS A O      1 ? 
ATOM   4053 C CB     A LYS A 1 246 ? 13.532  -4.878  2.757   1    26.839 ? 1254 LYS A CB     1 ? 
ATOM   4054 C CG     A LYS A 1 246 ? 13.126  -3.64   3.566   1    25.348 ? 1254 LYS A CG     1 ? 
ATOM   4055 C CD     A LYS A 1 246 ? 14.237  -2.587  3.557   1    28.166 ? 1254 LYS A CD     1 ? 
ATOM   4056 C CE     A LYS A 1 246 ? 13.598  -1.253  3.802   1    26.394 ? 1254 LYS A CE     1 ? 
ATOM   4057 N NZ     A LYS A 1 246 ? 14.59   -0.209  3.851   1    27.224 ? 1254 LYS A NZ     1 ? 
ATOM   4058 H H      . LYS A 1 246 ? 11.677  -5.906  1.499   1    26.842 ? 1254 LYS A H      1 ? 
ATOM   4059 H HA     A LYS A 1 246 ? 13.426  -3.624  1.029   1    24.614 ? 1254 LYS A HA     1 c 
ATOM   4060 H HB2    A LYS A 1 246 ? 12.896  -5.71   3.063   1    25.864 ? 1254 LYS A HB2    1 c 
ATOM   4061 H HB3    A LYS A 1 246 ? 14.561  -5.136  3.014   1    25.919 ? 1254 LYS A HB3    1 c 
ATOM   4062 H HG2    A LYS A 1 246 ? 12.217  -3.214  3.136   1    26.257 ? 1254 LYS A HG2    1 c 
ATOM   4063 H HG3    A LYS A 1 246 ? 12.916  -3.939  4.595   1    26.257 ? 1254 LYS A HG3    1 c 
ATOM   4064 H HD2    A LYS A 1 246 ? 14.961  -2.799  4.346   1    27.045 ? 1254 LYS A HD2    1 c 
ATOM   4065 H HD3    A LYS A 1 246 ? 14.742  -2.582  2.589   1    27.124 ? 1254 LYS A HD3    1 c 
ATOM   4066 H HE2    A LYS A 1 246 ? 12.885  -1.034  3.005   1    26.815 ? 1254 LYS A HE2    1 c 
ATOM   4067 H HE3    A LYS A 1 246 ? 13.067  -1.284  4.753   1    26.589 ? 1254 LYS A HE3    1 c 
ATOM   4068 H HZ1    . LYS A 1 246 ? 14.144  0.674   4.086   1    27.688 ? 1254 LYS A HZ1    1 ? 
ATOM   4069 H HZ2    . LYS A 1 246 ? 15.267  -0.443  4.559   1    27.084 ? 1254 LYS A HZ2    1 ? 
ATOM   4070 H HZ3    . LYS A 1 246 ? 15.047  -0.136  2.947   1    27.931 ? 1254 LYS A HZ3    1 ? 
ATOM   4071 N N      . ILE A 1 247 ? 14.402  -6.637  0.053   1    22.002 ? 1255 ILE A N      1 ? 
ATOM   4072 C CA     . ILE A 1 247 ? 15.245  -7.341  -0.905  1    22.819 ? 1255 ILE A CA     1 ? 
ATOM   4073 C C      . ILE A 1 247 ? 15.244  -6.611  -2.245  1    25.112 ? 1255 ILE A C      1 ? 
ATOM   4074 O O      . ILE A 1 247 ? 16.296  -6.386  -2.86   1    24.692 ? 1255 ILE A O      1 ? 
ATOM   4075 C CB     . ILE A 1 247 ? 14.816  -8.803  -1.069  1    24.153 ? 1255 ILE A CB     1 ? 
ATOM   4076 C CG1    . ILE A 1 247 ? 15.011  -9.578  0.239   1    22.514 ? 1255 ILE A CG1    1 ? 
ATOM   4077 C CG2    . ILE A 1 247 ? 15.577  -9.477  -2.219  1    24.612 ? 1255 ILE A CG2    1 ? 
ATOM   4078 C CD1    . ILE A 1 247 ? 14.395  -10.959 0.193   1    22.453 ? 1255 ILE A CD1    1 ? 
ATOM   4079 H H      . ILE A 1 247 ? 13.651  -7.171  0.529   0.5  20.962 ? 1255 ILE A H      1 ? 
ATOM   4080 H HA     . ILE A 1 247 ? 16.266  -7.335  -0.518  1    23.286 ? 1255 ILE A HA     1 c 
ATOM   4081 H HB     . ILE A 1 247 ? 13.753  -8.818  -1.312  1    23.627 ? 1255 ILE A HB     1 c 
ATOM   4082 H HG12   . ILE A 1 247 ? 16.08   -9.672  0.44    1    22.834 ? 1255 ILE A HG12   1 c 
ATOM   4083 H HG13   . ILE A 1 247 ? 14.561  -9.015  1.059   1    22.792 ? 1255 ILE A HG13   1 c 
ATOM   4084 H HG21   . ILE A 1 247 ? 15.33   -8.986  -3.162  1    24.473 ? 1255 ILE A HG21   1 c 
ATOM   4085 H HG22   . ILE A 1 247 ? 16.652  -9.399  -2.041  1    24.47  ? 1255 ILE A HG22   1 c 
ATOM   4086 H HG23   . ILE A 1 247 ? 15.296  -10.53  -2.279  1    24.425 ? 1255 ILE A HG23   1 c 
ATOM   4087 H HD11   . ILE A 1 247 ? 14.48   -11.428 1.175   1    22.476 ? 1255 ILE A HD11   1 c 
ATOM   4088 H HD12   . ILE A 1 247 ? 13.341  -10.88  -0.081  1    22.444 ? 1255 ILE A HD12   1 c 
ATOM   4089 H HD13   . ILE A 1 247 ? 14.915  -11.571 -0.546  1    22.529 ? 1255 ILE A HD13   1 c 
ATOM   4090 N N      . GLU A 1 248 ? 14.064  -6.188  -2.686  1    26.119 ? 1256 GLU A N      1 ? 
ATOM   4091 C CA     . GLU A 1 248 ? 13.935  -5.511  -3.973  1    25.937 ? 1256 GLU A CA     1 ? 
ATOM   4092 C C      . GLU A 1 248 ? 14.667  -4.167  -3.995  1    21.947 ? 1256 GLU A C      1 ? 
ATOM   4093 O O      . GLU A 1 248 ? 15.193  -3.771  -5.039  1    25.411 ? 1256 GLU A O      1 ? 
ATOM   4094 C CB     . GLU A 1 248 ? 12.457  -5.35   -4.338  1    26.753 ? 1256 GLU A CB     1 ? 
ATOM   4095 C CG     . GLU A 1 248 ? 12.226  -4.567  -5.627  1    27.519 ? 1256 GLU A CG     1 ? 
ATOM   4096 C CD     . GLU A 1 248 ? 10.801  -4.459  -6.115  1    33.109 ? 1256 GLU A CD     1 ? 
ATOM   4097 O OE1    . GLU A 1 248 ? 9.887   -5.19   -5.665  1    28.012 ? 1256 GLU A OE1    1 ? 
ATOM   4098 O OE2    . GLU A 1 248 ? 10.649  -3.627  -7.061  1    32.3   ? 1256 GLU A OE2    1 ? 
ATOM   4099 H H      . GLU A 1 248 ? 13.207  -6.376  -2.134  1    25.18  ? 1256 GLU A H      1 ? 
ATOM   4100 H HA     . GLU A 1 248 ? 14.391  -6.152  -4.731  1    25.349 ? 1256 GLU A HA     1 c 
ATOM   4101 H HB2    . GLU A 1 248 ? 12.011  -6.341  -4.442  1    26.732 ? 1256 GLU A HB2    1 c 
ATOM   4102 H HB3    . GLU A 1 248 ? 11.945  -4.84   -3.521  1    26.708 ? 1256 GLU A HB3    1 c 
ATOM   4103 H HG2    . GLU A 1 248 ? 12.61   -3.555  -5.492  1    28.434 ? 1256 GLU A HG2    1 c 
ATOM   4104 H HG3    . GLU A 1 248 ? 12.819  -5.027  -6.421  1    28.485 ? 1256 GLU A HG3    1 c 
ATOM   4105 N N      . GLU A 1 249 ? 14.726  -3.464  -2.865  1    22.183 ? 1257 GLU A N      1 ? 
ATOM   4106 C CA     . GLU A 1 249 ? 15.487  -2.225  -2.783  1    24.307 ? 1257 GLU A CA     1 ? 
ATOM   4107 C C      . GLU A 1 249 ? 16.967  -2.433  -3.11   1    23.902 ? 1257 GLU A C      1 ? 
ATOM   4108 O O      . GLU A 1 249 ? 17.645  -1.491  -3.534  1    25.939 ? 1257 GLU A O      1 ? 
ATOM   4109 C CB     . GLU A 1 249 ? 15.383  -1.558  -1.41   1    27.274 ? 1257 GLU A CB     1 ? 
ATOM   4110 C CG     . GLU A 1 249 ? 14.019  -0.958  -1.092  1    31.396 ? 1257 GLU A CG     1 ? 
ATOM   4111 C CD     . GLU A 1 249 ? 14.025  -0.104  0.166   1    34.431 ? 1257 GLU A CD     1 ? 
ATOM   4112 O OE1    . GLU A 1 249 ? 15.108  0.074   0.772   1    30.961 ? 1257 GLU A OE1    1 ? 
ATOM   4113 O OE2    . GLU A 1 249 ? 12.931  0.384   0.526   1    34.51  ? 1257 GLU A OE2    1 ? 
ATOM   4114 H H      . GLU A 1 249 ? 14.23   -3.825  -2.038  1    23.621 ? 1257 GLU A H      1 ? 
ATOM   4115 H HA     . GLU A 1 249 ? 15.075  -1.532  -3.519  1    24.312 ? 1257 GLU A HA     1 c 
ATOM   4116 H HB2    . GLU A 1 249 ? 15.627  -2.294  -0.643  1    27.415 ? 1257 GLU A HB2    1 c 
ATOM   4117 H HB3    . GLU A 1 249 ? 16.131  -0.764  -1.355  1    27.447 ? 1257 GLU A HB3    1 c 
ATOM   4118 H HG2    . GLU A 1 249 ? 13.693  -0.342  -1.933  1    31.113 ? 1257 GLU A HG2    1 c 
ATOM   4119 H HG3    . GLU A 1 249 ? 13.294  -1.763  -0.965  1    31.029 ? 1257 GLU A HG3    1 c 
ATOM   4120 N N      . TYR A 1 250 ? 17.472  -3.653  -2.914  1    22.638 ? 1258 TYR A N      1 ? 
ATOM   4121 C CA     . TYR A 1 250 ? 18.861  -3.989  -3.179  1    22.374 ? 1258 TYR A CA     1 ? 
ATOM   4122 C C      . TYR A 1 250 ? 18.962  -5.062  -4.263  1    22.266 ? 1258 TYR A C      1 ? 
ATOM   4123 O O      . TYR A 1 250 ? 19.866  -5.888  -4.233  1    21.635 ? 1258 TYR A O      1 ? 
ATOM   4124 C CB     . TYR A 1 250 ? 19.538  -4.477  -1.901  1    22.071 ? 1258 TYR A CB     1 ? 
ATOM   4125 C CG     . TYR A 1 250 ? 19.533  -3.477  -0.766  1    21.317 ? 1258 TYR A CG     1 ? 
ATOM   4126 C CD1    . TYR A 1 250 ? 20.484  -2.472  -0.69   1    19.999 ? 1258 TYR A CD1    1 ? 
ATOM   4127 C CD2    . TYR A 1 250 ? 18.568  -3.552  0.23    1    24.568 ? 1258 TYR A CD2    1 ? 
ATOM   4128 C CE1    . TYR A 1 250 ? 20.488  -1.573  0.366   1    19.641 ? 1258 TYR A CE1    1 ? 
ATOM   4129 C CE2    . TYR A 1 250 ? 18.569  -2.659  1.288   1    24.415 ? 1258 TYR A CE2    1 ? 
ATOM   4130 C CZ     . TYR A 1 250 ? 19.534  -1.679  1.36    1    21.44  ? 1258 TYR A CZ     1 ? 
ATOM   4131 O OH     . TYR A 1 250 ? 19.559  -0.795  2.418   1    22.387 ? 1258 TYR A OH     1 ? 
ATOM   4132 H H      . TYR A 1 250 ? 16.877  -4.401  -2.504  1    22.17  ? 1258 TYR A H      1 ? 
ATOM   4133 H HA     . TYR A 1 250 ? 19.376  -3.092  -3.524  1    22.395 ? 1258 TYR A HA     1 c 
ATOM   4134 H HB2    . TYR A 1 250 ? 19.036  -5.388  -1.569  1    21.968 ? 1258 TYR A HB2    1 c 
ATOM   4135 H HB3    . TYR A 1 250 ? 20.573  -4.735  -2.135  1    21.966 ? 1258 TYR A HB3    1 c 
ATOM   4136 H HD1    . TYR A 1 250 ? 21.246  -2.398  -1.457  1    20.292 ? 1258 TYR A HD1    1 c 
ATOM   4137 H HD2    . TYR A 1 250 ? 17.82   -4.337  0.193   1    23.72  ? 1258 TYR A HD2    1 c 
ATOM   4138 H HE1    . TYR A 1 250 ? 21.249  -0.802  0.423   1    20.166 ? 1258 TYR A HE1    1 c 
ATOM   4139 H HE2    . TYR A 1 250 ? 17.822  -2.742  2.071   1    23.665 ? 1258 TYR A HE2    1 c 
ATOM   4140 H HH     . TYR A 1 250 ? 19.046  -1.038  3.198   1    21.946 ? 1258 TYR A HH     1 ? 
ATOM   4141 N N      . SER A 1 251 ? 18.026  -5.043  -5.238  1    21.199 ? 1259 SER A N      1 ? 
ATOM   4142 C CA     . SER A 1 251 ? 17.934  -5.986  -6.347  1    21.785 ? 1259 SER A CA     1 ? 
ATOM   4143 C C      . SER A 1 251 ? 19.291  -6.334  -6.92   1    20.584 ? 1259 SER A C      1 ? 
ATOM   4144 O O      . SER A 1 251 ? 19.698  -7.478  -7.042  1    19.364 ? 1259 SER A O      1 ? 
ATOM   4145 C CB     . SER A 1 251 ? 17.095  -5.403  -7.481  1    24.272 ? 1259 SER A CB     1 ? 
ATOM   4146 O OG     . SER A 1 251 ? 15.724  -5.343  -7.123  1    27.133 ? 1259 SER A OG     1 ? 
ATOM   4147 H H      . SER A 1 251 ? 17.272  -4.341  -5.165  1    22.755 ? 1259 SER A H      1 ? 
ATOM   4148 H HA     . SER A 1 251 ? 17.459  -6.901  -5.989  1    21.869 ? 1259 SER A HA     1 c 
ATOM   4149 H HB2    . SER A 1 251 ? 17.452  -4.401  -7.722  1    24.431 ? 1259 SER A HB2    1 c 
ATOM   4150 H HB3    . SER A 1 251 ? 17.209  -6.028  -8.369  1    24.416 ? 1259 SER A HB3    1 c 
ATOM   4151 H HG     . SER A 1 251 ? 15.638  -4.799  -6.315  1    25.232 ? 1259 SER A HG     1 ? 
ATOM   4152 N N      . ASP A 1 252 ? 19.916  -5.289  -7.419  1    21.103 ? 1260 ASP A N      1 ? 
ATOM   4153 C CA     . ASP A 1 252 ? 21.146  -5.437  -8.179  1    20.319 ? 1260 ASP A CA     1 ? 
ATOM   4154 C C      . ASP A 1 252 ? 22.258  -6.009  -7.31   1    19.737 ? 1260 ASP A C      1 ? 
ATOM   4155 O O      . ASP A 1 252 ? 22.958  -6.961  -7.692  1    19.033 ? 1260 ASP A O      1 ? 
ATOM   4156 C CB     . ASP A 1 252 ? 21.499  -4.148  -8.901  1    23.282 ? 1260 ASP A CB     1 ? 
ATOM   4157 C CG     . ASP A 1 252 ? 22.642  -4.324  -9.902  1    24.046 ? 1260 ASP A CG     1 ? 
ATOM   4158 O OD1    . ASP A 1 252 ? 22.708  -5.402  -10.519 1    24.461 ? 1260 ASP A OD1    1 ? 
ATOM   4159 O OD2    . ASP A 1 252 ? 23.422  -3.381  -10.091 1    28.404 ? 1260 ASP A OD2    1 ? 
ATOM   4160 H H      . ASP A 1 252 ? 19.489  -4.352  -7.31   1    19.621 ? 1260 ASP A H      1 ? 
ATOM   4161 H HA     . ASP A 1 252 ? 20.949  -6.164  -8.968  1    20.91  ? 1260 ASP A HA     1 c 
ATOM   4162 H HB2    . ASP A 1 252 ? 20.62   -3.783  -9.437  1    22.759 ? 1260 ASP A HB2    1 c 
ATOM   4163 H HB3    . ASP A 1 252 ? 21.792  -3.393  -8.168  1    22.759 ? 1260 ASP A HB3    1 c 
ATOM   4164 N N      . GLU A 1 253 ? 22.447  -5.421  -6.121  1    19.2   ? 1261 GLU A N      1 ? 
ATOM   4165 C CA     . GLU A 1 253 ? 23.479  -5.905  -5.226  1    18.503 ? 1261 GLU A CA     1 ? 
ATOM   4166 C C      . GLU A 1 253 ? 23.26   -7.372  -4.879  1    16.193 ? 1261 GLU A C      1 ? 
ATOM   4167 O O      . GLU A 1 253 ? 24.207  -8.17   -4.896  1    19.355 ? 1261 GLU A O      1 ? 
ATOM   4168 C CB     . GLU A 1 253 ? 23.5    -5.056  -3.952  1    20.89  ? 1261 GLU A CB     1 ? 
ATOM   4169 C CG     . GLU A 1 253 ? 24.086  -3.667  -4.135  1    23.181 ? 1261 GLU A CG     1 ? 
ATOM   4170 C CD     . GLU A 1 253 ? 24.43   -2.989  -2.839  1    23.438 ? 1261 GLU A CD     1 ? 
ATOM   4171 O OE1    . GLU A 1 253 ? 25.596  -3.153  -2.463  1    26.107 ? 1261 GLU A OE1    1 ? 
ATOM   4172 O OE2    . GLU A 1 253 ? 23.605  -2.347  -2.167  1    24.956 ? 1261 GLU A OE2    1 ? 
ATOM   4173 H H      . GLU A 1 253 ? 21.852  -4.641  -5.793  1    18.99  ? 1261 GLU A H      1 ? 
ATOM   4174 H HA     . GLU A 1 253 ? 24.44   -5.804  -5.731  1    18.636 ? 1261 GLU A HA     1 c 
ATOM   4175 H HB2    . GLU A 1 253 ? 22.478  -4.957  -3.581  1    20.816 ? 1261 GLU A HB2    1 c 
ATOM   4176 H HB3    . GLU A 1 253 ? 24.079  -5.582  -3.191  1    20.816 ? 1261 GLU A HB3    1 c 
ATOM   4177 H HG2    . GLU A 1 253 ? 24.993  -3.74   -4.74   1    22.722 ? 1261 GLU A HG2    1 c 
ATOM   4178 H HG3    . GLU A 1 253 ? 23.376  -3.044  -4.678  1    22.743 ? 1261 GLU A HG3    1 c 
ATOM   4179 N N      . ILE A 1 254 ? 22.012  -7.739  -4.563  1    15.745 ? 1262 ILE A N      1 ? 
ATOM   4180 C CA     . ILE A 1 254 ? 21.679  -9.097  -4.148  1    17.077 ? 1262 ILE A CA     1 ? 
ATOM   4181 C C      . ILE A 1 254 ? 21.949  -10.077 -5.292  1    17.085 ? 1262 ILE A C      1 ? 
ATOM   4182 O O      . ILE A 1 254 ? 22.579  -11.103 -5.073  1    14.819 ? 1262 ILE A O      1 ? 
ATOM   4183 C CB     . ILE A 1 254 ? 20.224  -9.241  -3.629  1    19.06  ? 1262 ILE A CB     1 ? 
ATOM   4184 C CG1    . ILE A 1 254 ? 19.935  -8.477  -2.329  1    19.714 ? 1262 ILE A CG1    1 ? 
ATOM   4185 C CG2    . ILE A 1 254 ? 19.846  -10.709 -3.458  1    17.749 ? 1262 ILE A CG2    1 ? 
ATOM   4186 C CD1    . ILE A 1 254 ? 20.923  -8.735  -1.203  1    23.338 ? 1262 ILE A CD1    1 ? 
ATOM   4187 H H      . ILE A 1 254 ? 21.25   -7.04   -4.631  1    16.243 ? 1262 ILE A H      1 ? 
ATOM   4188 H HA     . ILE A 1 254 ? 22.349  -9.36   -3.327  1    17.209 ? 1262 ILE A HA     1 c 
ATOM   4189 H HB     . ILE A 1 254 ? 19.568  -8.826  -4.397  1    18.563 ? 1262 ILE A HB     1 c 
ATOM   4190 H HG12   . ILE A 1 254 ? 19.93   -7.407  -2.546  1    20.322 ? 1262 ILE A HG12   1 c 
ATOM   4191 H HG13   . ILE A 1 254 ? 18.935  -8.748  -1.982  1    20.313 ? 1262 ILE A HG13   1 c 
ATOM   4192 H HG21   . ILE A 1 254 ? 18.877  -10.779 -2.958  1    18.094 ? 1262 ILE A HG21   1 c 
ATOM   4193 H HG22   . ILE A 1 254 ? 19.782  -11.191 -4.436  1    18.089 ? 1262 ILE A HG22   1 c 
ATOM   4194 H HG23   . ILE A 1 254 ? 20.601  -11.214 -2.852  1    18.071 ? 1262 ILE A HG23   1 c 
ATOM   4195 H HD11   . ILE A 1 254 ? 21.917  -8.39   -1.496  1    22.164 ? 1262 ILE A HD11   1 c 
ATOM   4196 H HD12   . ILE A 1 254 ? 20.603  -8.195  -0.309  1    22.223 ? 1262 ILE A HD12   1 c 
ATOM   4197 H HD13   . ILE A 1 254 ? 20.959  -9.804  -0.986  1    22.154 ? 1262 ILE A HD13   1 c 
ATOM   4198 N N      . PHE A 1 255 ? 21.45   -9.779  -6.495  1    16.48  ? 1263 PHE A N      1 ? 
ATOM   4199 C CA     . PHE A 1 255 ? 21.61   -10.701 -7.605  1    15.619 ? 1263 PHE A CA     1 ? 
ATOM   4200 C C      . PHE A 1 255 ? 23.089  -10.872 -7.953  1    17.269 ? 1263 PHE A C      1 ? 
ATOM   4201 O O      . PHE A 1 255 ? 23.544  -11.986 -8.256  1    16.729 ? 1263 PHE A O      1 ? 
ATOM   4202 C CB     . PHE A 1 255 ? 20.769  -10.275 -8.809  1    16.632 ? 1263 PHE A CB     1 ? 
ATOM   4203 C CG     . PHE A 1 255 ? 19.377  -10.858 -8.794  1    17.504 ? 1263 PHE A CG     1 ? 
ATOM   4204 C CD1    . PHE A 1 255 ? 18.548  -10.683 -7.689  1    18.177 ? 1263 PHE A CD1    1 ? 
ATOM   4205 C CD2    . PHE A 1 255 ? 18.917  -11.621 -9.857  1    16.87  ? 1263 PHE A CD2    1 ? 
ATOM   4206 C CE1    . PHE A 1 255 ? 17.283  -11.248 -7.668  1    19.293 ? 1263 PHE A CE1    1 ? 
ATOM   4207 C CE2    . PHE A 1 255 ? 17.648  -12.163 -9.836  1    17.379 ? 1263 PHE A CE2    1 ? 
ATOM   4208 C CZ     . PHE A 1 255 ? 16.822  -11.969 -8.756  1    18.074 ? 1263 PHE A CZ     1 ? 
ATOM   4209 H H      . PHE A 1 255 ? 20.914  -8.903  -6.62   1    18.197 ? 1263 PHE A H      1 ? 
ATOM   4210 H HA     . PHE A 1 255 ? 21.237  -11.673 -7.275  1    16.244 ? 1263 PHE A HA     1 c 
ATOM   4211 H HB2    . PHE A 1 255 ? 20.698  -9.185  -8.818  1    16.592 ? 1263 PHE A HB2    1 c 
ATOM   4212 H HB3    . PHE A 1 255 ? 21.278  -10.591 -9.721  1    16.592 ? 1263 PHE A HB3    1 c 
ATOM   4213 H HD1    . PHE A 1 255 ? 18.898  -10.106 -6.839  1    18.231 ? 1263 PHE A HD1    1 c 
ATOM   4214 H HD2    . PHE A 1 255 ? 19.551  -11.767 -10.725 1    17.139 ? 1263 PHE A HD2    1 c 
ATOM   4215 H HE1    . PHE A 1 255 ? 16.636  -11.089 -6.812  1    18.737 ? 1263 PHE A HE1    1 c 
ATOM   4216 H HE2    . PHE A 1 255 ? 17.297  -12.74  -10.685 1    17.432 ? 1263 PHE A HE2    1 c 
ATOM   4217 H HZ     . PHE A 1 255 ? 15.831  -12.41  -8.739  1    18.162 ? 1263 PHE A HZ     1 c 
ATOM   4218 N N      . LYS A 1 256 ? 23.865  -9.768  -7.882  1    17.788 ? 1264 LYS A N      1 ? 
ATOM   4219 C CA     . LYS A 1 256 ? 25.297  -9.809  -8.086  1    19.895 ? 1264 LYS A CA     1 ? 
ATOM   4220 C C      . LYS A 1 256 ? 25.969  -10.73  -7.06   1    19.646 ? 1264 LYS A C      1 ? 
ATOM   4221 O O      . LYS A 1 256 ? 26.838  -11.532 -7.405  1    17.357 ? 1264 LYS A O      1 ? 
ATOM   4222 C CB     . LYS A 1 256 ? 25.96   -8.419  -8.085  1    23.313 ? 1264 LYS A CB     1 ? 
ATOM   4223 C CG     . LYS A 1 256 ? 25.854  -7.645  -9.434  1    26.453 ? 1264 LYS A CG     1 ? 
ATOM   4224 C CD     . LYS A 1 256 ? 26.406  -6.229  -9.333  1    29.263 ? 1264 LYS A CD     1 ? 
ATOM   4225 C CE     . LYS A 1 256 ? 26.706  -5.508  -10.591 1    32.499 ? 1264 LYS A CE     1 ? 
ATOM   4226 N NZ     . LYS A 1 256 ? 25.472  -5.298  -11.355 1    37.553 ? 1264 LYS A NZ     1 ? 
ATOM   4227 H H      . LYS A 1 256 ? 23.439  -8.875  -7.589  1    18.511 ? 1264 LYS A H      1 ? 
ATOM   4228 H HA     . LYS A 1 256 ? 25.471  -10.239 -9.075  1    20.007 ? 1264 LYS A HA     1 c 
ATOM   4229 H HB2    . LYS A 1 256 ? 25.498  -7.813  -7.304  1    23.16  ? 1264 LYS A HB2    1 c 
ATOM   4230 H HB3    . LYS A 1 256 ? 27.017  -8.534  -7.834  1    23.145 ? 1264 LYS A HB3    1 c 
ATOM   4231 H HG2    . LYS A 1 256 ? 26.405  -8.194  -10.2   1    26.432 ? 1264 LYS A HG2    1 c 
ATOM   4232 H HG3    . LYS A 1 256 ? 24.804  -7.602  -9.734  1    26.344 ? 1264 LYS A HG3    1 c 
ATOM   4233 H HD2    . LYS A 1 256 ? 25.692  -5.634  -8.76   1    29.308 ? 1264 LYS A HD2    1 c 
ATOM   4234 H HD3    . LYS A 1 256 ? 27.321  -6.272  -8.738  1    29.308 ? 1264 LYS A HD3    1 c 
ATOM   4235 H HE2    . LYS A 1 256 ? 27.158  -4.539  -10.376 1    32.813 ? 1264 LYS A HE2    1 c 
ATOM   4236 H HE3    . LYS A 1 256 ? 27.407  -6.088  -11.195 1    32.807 ? 1264 LYS A HE3    1 c 
ATOM   4237 H HZ1    . LYS A 1 256 ? 25.721  -4.94   -12.271 1    36.385 ? 1264 LYS A HZ1    1 ? 
ATOM   4238 H HZ2    . LYS A 1 256 ? 24.932  -6.175  -11.49  1    34.702 ? 1264 LYS A HZ2    1 ? 
ATOM   4239 H HZ3    . LYS A 1 256 ? 24.916  -4.607  -10.863 1    35.768 ? 1264 LYS A HZ3    1 ? 
ATOM   4240 N N      . LEU A 1 257 ? 25.541  -10.646 -5.793  1    17.896 ? 1265 LEU A N      1 ? 
ATOM   4241 C CA     . LEU A 1 257 ? 26.123  -11.485 -4.755  1    17.329 ? 1265 LEU A CA     1 ? 
ATOM   4242 C C      . LEU A 1 257 ? 25.79   -12.954 -4.99   1    16.761 ? 1265 LEU A C      1 ? 
ATOM   4243 O O      . LEU A 1 257 ? 26.638  -13.832 -4.816  1    15.217 ? 1265 LEU A O      1 ? 
ATOM   4244 C CB     . LEU A 1 257 ? 25.641  -11.032 -3.379  1    16.717 ? 1265 LEU A CB     1 ? 
ATOM   4245 C CG     . LEU A 1 257 ? 26.237  -9.715  -2.879  1    16.577 ? 1265 LEU A CG     1 ? 
ATOM   4246 C CD1    . LEU A 1 257 ? 25.514  -9.258  -1.627  1    16.167 ? 1265 LEU A CD1    1 ? 
ATOM   4247 C CD2    . LEU A 1 257 ? 27.742  -9.826  -2.639  1    17.991 ? 1265 LEU A CD2    1 ? 
ATOM   4248 H H      . LEU A 1 257 ? 24.819  -9.951  -5.537  1    18.137 ? 1265 LEU A H      1 ? 
ATOM   4249 H HA     . LEU A 1 257 ? 27.208  -11.374 -4.804  1    17.229 ? 1265 LEU A HA     1 c 
ATOM   4250 H HB2    . LEU A 1 257 ? 24.554  -10.929 -3.414  1    16.806 ? 1265 LEU A HB2    1 c 
ATOM   4251 H HB3    . LEU A 1 257 ? 25.881  -11.816 -2.657  1    16.816 ? 1265 LEU A HB3    1 c 
ATOM   4252 H HG     . LEU A 1 257 ? 26.08   -8.961  -3.649  1    16.861 ? 1265 LEU A HG     1 c 
ATOM   4253 H HD11   . LEU A 1 257 ? 24.455  -9.11   -1.85   1    16.282 ? 1265 LEU A HD11   1 c 
ATOM   4254 H HD12   . LEU A 1 257 ? 25.619  -10.016 -0.848  1    16.282 ? 1265 LEU A HD12   1 c 
ATOM   4255 H HD13   . LEU A 1 257 ? 25.946  -8.318  -1.278  1    16.288 ? 1265 LEU A HD13   1 c 
ATOM   4256 H HD21   . LEU A 1 257 ? 28.119  -8.882  -2.241  1    17.581 ? 1265 LEU A HD21   1 c 
ATOM   4257 H HD22   . LEU A 1 257 ? 27.939  -10.627 -1.924  1    17.581 ? 1265 LEU A HD22   1 c 
ATOM   4258 H HD23   . LEU A 1 257 ? 28.247  -10.049 -3.581  1    17.561 ? 1265 LEU A HD23   1 c 
ATOM   4259 N N      . LEU A 1 258 ? 24.527  -13.249 -5.361  1    16.798 ? 1266 LEU A N      1 ? 
ATOM   4260 C CA     . LEU A 1 258 ? 24.138  -14.619 -5.653  1    16.714 ? 1266 LEU A CA     1 ? 
ATOM   4261 C C      . LEU A 1 258 ? 24.969  -15.185 -6.799  1    17.959 ? 1266 LEU A C      1 ? 
ATOM   4262 O O      . LEU A 1 258 ? 25.46   -16.319 -6.726  1    17.107 ? 1266 LEU A O      1 ? 
ATOM   4263 C CB     . LEU A 1 258 ? 22.654  -14.677 -5.985  1    16.391 ? 1266 LEU A CB     1 ? 
ATOM   4264 C CG     . LEU A 1 258 ? 21.692  -14.422 -4.826  1    16.681 ? 1266 LEU A CG     1 ? 
ATOM   4265 C CD1    . LEU A 1 258 ? 20.264  -14.237 -5.355  1    17.121 ? 1266 LEU A CD1    1 ? 
ATOM   4266 C CD2    . LEU A 1 258 ? 21.798  -15.546 -3.778  1    17.428 ? 1266 LEU A CD2    1 ? 
ATOM   4267 H H      . LEU A 1 258 ? 23.821  -12.497 -5.456  1    16.786 ? 1266 LEU A H      1 ? 
ATOM   4268 H HA     . LEU A 1 258 ? 24.328  -15.222 -4.763  1    16.892 ? 1266 LEU A HA     1 c 
ATOM   4269 H HB2    . LEU A 1 258 ? 22.452  -13.942 -6.767  1    16.525 ? 1266 LEU A HB2    1 c 
ATOM   4270 H HB3    . LEU A 1 258 ? 22.437  -15.664 -6.399  1    16.525 ? 1266 LEU A HB3    1 c 
ATOM   4271 H HG     . LEU A 1 258 ? 21.989  -13.489 -4.342  1    16.826 ? 1266 LEU A HG     1 c 
ATOM   4272 H HD11   . LEU A 1 258 ? 20.236  -13.387 -6.04   1    16.996 ? 1266 LEU A HD11   1 c 
ATOM   4273 H HD12   . LEU A 1 258 ? 19.951  -15.14  -5.884  1    16.996 ? 1266 LEU A HD12   1 c 
ATOM   4274 H HD13   . LEU A 1 258 ? 19.586  -14.053 -4.519  1    16.987 ? 1266 LEU A HD13   1 c 
ATOM   4275 H HD21   . LEU A 1 258 ? 21.077  -15.368 -2.978  1    17.213 ? 1266 LEU A HD21   1 c 
ATOM   4276 H HD22   . LEU A 1 258 ? 21.585  -16.507 -4.251  1    17.213 ? 1266 LEU A HD22   1 c 
ATOM   4277 H HD23   . LEU A 1 258 ? 22.806  -15.563 -3.36   1    17.194 ? 1266 LEU A HD23   1 c 
ATOM   4278 N N      . ASP A 1 259 ? 25.155  -14.39  -7.863  1    17.48  ? 1267 ASP A N      1 ? 
ATOM   4279 C CA     . ASP A 1 259 ? 25.966  -14.84  -8.986  1    19.765 ? 1267 ASP A CA     1 ? 
ATOM   4280 C C      . ASP A 1 259 ? 27.411  -15.104 -8.569  1    18.641 ? 1267 ASP A C      1 ? 
ATOM   4281 O O      . ASP A 1 259 ? 28.093  -15.939 -9.167  1    21.815 ? 1267 ASP A O      1 ? 
ATOM   4282 C CB     . ASP A 1 259 ? 25.936  -13.821 -10.118 1    19.614 ? 1267 ASP A CB     1 ? 
ATOM   4283 C CG     . ASP A 1 259 ? 24.619  -13.731 -10.846 1    21.845 ? 1267 ASP A CG     1 ? 
ATOM   4284 O OD1    . ASP A 1 259 ? 23.735  -14.586 -10.612 1    21.886 ? 1267 ASP A OD1    1 ? 
ATOM   4285 O OD2    . ASP A 1 259 ? 24.476  -12.803 -11.67  1    24.576 ? 1267 ASP A OD2    1 ? 
ATOM   4286 H H      . ASP A 1 259 ? 24.693  -13.466 -7.889  1    17.608 ? 1267 ASP A H      1 ? 
ATOM   4287 H HA     . ASP A 1 259 ? 25.542  -15.773 -9.36   1    19.162 ? 1267 ASP A HA     1 c 
ATOM   4288 H HB2    . ASP A 1 259 ? 26.167  -12.836 -9.709  1    20.143 ? 1267 ASP A HB2    1 c 
ATOM   4289 H HB3    . ASP A 1 259 ? 26.712  -14.076 -10.843 1    20.126 ? 1267 ASP A HB3    1 c 
ATOM   4290 N N      . GLY A 1 260 ? 27.895  -14.372 -7.57   1    17.546 ? 1268 GLY A N      1 ? 
ATOM   4291 C CA     . GLY A 1 260 ? 29.234  -14.567 -7.052  1    18.538 ? 1268 GLY A CA     1 ? 
ATOM   4292 C C      . GLY A 1 260 ? 29.379  -15.695 -6.046  1    17.23  ? 1268 GLY A C      1 ? 
ATOM   4293 O O      . GLY A 1 260 ? 30.474  -15.902 -5.534  1    15.337 ? 1268 GLY A O      1 ? 
ATOM   4294 H H      . GLY A 1 260 ? 27.367  -13.535 -7.273  1    18.398 ? 1268 GLY A H      1 ? 
ATOM   4295 H HA2    . GLY A 1 260 ? 29.906  -14.755 -7.892  1    18.023 ? 1268 GLY A HA2    1 c 
ATOM   4296 H HA3    . GLY A 1 260 ? 29.556  -13.635 -6.582  1    17.94  ? 1268 GLY A HA3    1 c 
ATOM   4297 N N      . GLY A 1 261 ? 28.305  -16.418 -5.749  1    16.462 ? 1269 GLY A N      1 ? 
ATOM   4298 C CA     . GLY A 1 261 ? 28.39   -17.567 -4.873  1    15.412 ? 1269 GLY A CA     1 ? 
ATOM   4299 C C      . GLY A 1 261 ? 27.787  -17.408 -3.486  1    15.348 ? 1269 GLY A C      1 ? 
ATOM   4300 O O      . GLY A 1 261 ? 27.962  -18.298 -2.649  1    16.294 ? 1269 GLY A O      1 ? 
ATOM   4301 H H      . GLY A 1 261 ? 27.395  -16.215 -6.201  1    17.179 ? 1269 GLY A H      1 ? 
ATOM   4302 H HA2    . GLY A 1 261 ? 27.9    -18.407 -5.369  1    15.639 ? 1269 GLY A HA2    1 c 
ATOM   4303 H HA3    . GLY A 1 261 ? 29.443  -17.831 -4.762  1    15.659 ? 1269 GLY A HA3    1 c 
ATOM   4304 N N      . ALA A 1 262 ? 27.072  -16.324 -3.221  1    14.56  ? 1270 ALA A N      1 ? 
ATOM   4305 C CA     . ALA A 1 262 ? 26.514  -16.113 -1.894  1    14.504 ? 1270 ALA A CA     1 ? 
ATOM   4306 C C      . ALA A 1 262 ? 25.512  -17.206 -1.531  1    15.316 ? 1270 ALA A C      1 ? 
ATOM   4307 O O      . ALA A 1 262 ? 24.755  -17.697 -2.367  1    14.561 ? 1270 ALA A O      1 ? 
ATOM   4308 C CB     . ALA A 1 262 ? 25.827  -14.758 -1.832  1    15.036 ? 1270 ALA A CB     1 ? 
ATOM   4309 H H      . ALA A 1 262 ? 26.886  -15.616 -3.949  1    14.031 ? 1270 ALA A H      1 ? 
ATOM   4310 H HA     . ALA A 1 262 ? 27.33   -16.139 -1.169  1    14.747 ? 1270 ALA A HA     1 c 
ATOM   4311 H HB1    . ALA A 1 262 ? 26.551  -13.969 -2.045  1    14.885 ? 1270 ALA A HB1    1 c 
ATOM   4312 H HB2    . ALA A 1 262 ? 25.023  -14.719 -2.569  1    14.885 ? 1270 ALA A HB2    1 c 
ATOM   4313 H HB3    . ALA A 1 262 ? 25.409  -14.604 -0.835  1    14.88  ? 1270 ALA A HB3    1 c 
ATOM   4314 N N      . HIS A 1 263 ? 25.497  -17.546 -0.249  1    15.024 ? 1271 HIS A N      1 ? 
ATOM   4315 C CA     . HIS A 1 263 ? 24.43   -18.338 0.326   1    14.163 ? 1271 HIS A CA     1 ? 
ATOM   4316 C C      . HIS A 1 263 ? 23.274  -17.431 0.697   1    14.9   ? 1271 HIS A C      1 ? 
ATOM   4317 O O      . HIS A 1 263 ? 23.475  -16.311 1.166   1    13.676 ? 1271 HIS A O      1 ? 
ATOM   4318 C CB     . HIS A 1 263 ? 24.934  -19.053 1.577   1    13.581 ? 1271 HIS A CB     1 ? 
ATOM   4319 C CG     . HIS A 1 263 ? 25.934  -20.107 1.273   1    15.545 ? 1271 HIS A CG     1 ? 
ATOM   4320 N ND1    . HIS A 1 263 ? 25.566  -21.359 0.828   1    15.152 ? 1271 HIS A ND1    1 ? 
ATOM   4321 C CD2    . HIS A 1 263 ? 27.279  -20.09  1.284   1    16.115 ? 1271 HIS A CD2    1 ? 
ATOM   4322 C CE1    . HIS A 1 263 ? 26.654  -22.07  0.593   1    15.897 ? 1271 HIS A CE1    1 ? 
ATOM   4323 N NE2    . HIS A 1 263 ? 27.705  -21.322 0.85    1    16.179 ? 1271 HIS A NE2    1 ? 
ATOM   4324 H H      . HIS A 1 263 ? 26.177  -17.109 0.394   1    14.504 ? 1271 HIS A H      1 ? 
ATOM   4325 H HA     . HIS A 1 263 ? 24.083  -19.068 -0.408  1    14.339 ? 1271 HIS A HA     1 c 
ATOM   4326 H HB2    . HIS A 1 263 ? 25.385  -18.316 2.245   1    14.125 ? 1271 HIS A HB2    1 c 
ATOM   4327 H HB3    . HIS A 1 263 ? 24.084  -19.505 2.091   1    14.125 ? 1271 HIS A HB3    1 c 
ATOM   4328 H HD2    . HIS A 1 263 ? 27.917  -19.253 1.546   1    15.989 ? 1271 HIS A HD2    1 c 
ATOM   4329 H HE1    . HIS A 1 263 ? 26.675  -23.097 0.245   1    15.919 ? 1271 HIS A HE1    1 c 
ATOM   4330 H HE2    . HIS A 1 263 ? 28.681  -21.56  0.749   1    16.488 ? 1271 HIS A HE2    1 ? 
ATOM   4331 N N      . ILE A 1 264 ? 22.057  -17.934 0.514   1    13.794 ? 1272 ILE A N      1 ? 
ATOM   4332 C CA     . ILE A 1 264 ? 20.865  -17.21  0.916   1    14.383 ? 1272 ILE A CA     1 ? 
ATOM   4333 C C      . ILE A 1 264 ? 19.969  -18.153 1.719   1    14.632 ? 1272 ILE A C      1 ? 
ATOM   4334 O O      . ILE A 1 264 ? 19.816  -19.33  1.376   1    14.297 ? 1272 ILE A O      1 ? 
ATOM   4335 C CB     . ILE A 1 264 ? 20.152  -16.544 -0.284  1    16.068 ? 1272 ILE A CB     1 ? 
ATOM   4336 C CG1    . ILE A 1 264 ? 19.018  -15.624 0.201   1    15.928 ? 1272 ILE A CG1    1 ? 
ATOM   4337 C CG2    . ILE A 1 264 ? 19.676  -17.575 -1.311  1    16.562 ? 1272 ILE A CG2    1 ? 
ATOM   4338 C CD1    . ILE A 1 264 ? 18.55   -14.637 -0.855  1    15.758 ? 1272 ILE A CD1    1 ? 
ATOM   4339 H H      . ILE A 1 264 ? 21.973  -18.853 0.036   1    13.507 ? 1272 ILE A H      1 ? 
ATOM   4340 H HA     . ILE A 1 264 ? 21.181  -16.411 1.585   1    14.586 ? 1272 ILE A HA     1 c 
ATOM   4341 H HB     . ILE A 1 264 ? 20.888  -15.909 -0.781  1    15.813 ? 1272 ILE A HB     1 c 
ATOM   4342 H HG12   . ILE A 1 264 ? 18.171  -16.24  0.509   1    15.906 ? 1272 ILE A HG12   1 c 
ATOM   4343 H HG13   . ILE A 1 264 ? 19.364  -15.068 1.075   1    15.907 ? 1272 ILE A HG13   1 c 
ATOM   4344 H HG21   . ILE A 1 264 ? 19.207  -17.063 -2.154  1    16.407 ? 1272 ILE A HG21   1 c 
ATOM   4345 H HG22   . ILE A 1 264 ? 20.529  -18.155 -1.67   1    16.407 ? 1272 ILE A HG22   1 c 
ATOM   4346 H HG23   . ILE A 1 264 ? 18.95   -18.248 -0.848  1    16.356 ? 1272 ILE A HG23   1 c 
ATOM   4347 H HD11   . ILE A 1 264 ? 18.179  -15.182 -1.726  1    15.806 ? 1272 ILE A HD11   1 c 
ATOM   4348 H HD12   . ILE A 1 264 ? 17.748  -14.018 -0.448  1    15.806 ? 1272 ILE A HD12   1 c 
ATOM   4349 H HD13   . ILE A 1 264 ? 19.383  -13.999 -1.155  1    15.812 ? 1272 ILE A HD13   1 c 
ATOM   4350 N N      . TYR A 1 265 ? 19.43   -17.635 2.823   1    14.493 ? 1273 TYR A N      1 ? 
ATOM   4351 C CA     . TYR A 1 265 ? 18.706  -18.414 3.818   1    14.982 ? 1273 TYR A CA     1 ? 
ATOM   4352 C C      . TYR A 1 265 ? 17.347  -17.779 4.052   1    15.225 ? 1273 TYR A C      1 ? 
ATOM   4353 O O      . TYR A 1 265 ? 17.226  -16.552 4.076   1    16.296 ? 1273 TYR A O      1 ? 
ATOM   4354 C CB     . TYR A 1 265 ? 19.434  -18.389 5.178   1    14.928 ? 1273 TYR A CB     1 ? 
ATOM   4355 C CG     . TYR A 1 265 ? 20.89   -18.807 5.109   1    14.604 ? 1273 TYR A CG     1 ? 
ATOM   4356 C CD1    . TYR A 1 265 ? 21.863  -17.914 4.661   1    13.738 ? 1273 TYR A CD1    1 ? 
ATOM   4357 C CD2    . TYR A 1 265 ? 21.291  -20.093 5.455   1    14.618 ? 1273 TYR A CD2    1 ? 
ATOM   4358 C CE1    . TYR A 1 265 ? 23.189  -18.281 4.574   1    14     ? 1273 TYR A CE1    1 ? 
ATOM   4359 C CE2    . TYR A 1 265 ? 22.627  -20.474 5.374   1    14.715 ? 1273 TYR A CE2    1 ? 
ATOM   4360 C CZ     . TYR A 1 265 ? 23.568  -19.568 4.921   1    14.881 ? 1273 TYR A CZ     1 ? 
ATOM   4361 O OH     . TYR A 1 265 ? 24.876  -19.957 4.836   1    16.616 ? 1273 TYR A OH     1 ? 
ATOM   4362 H H      . TYR A 1 265 ? 19.571  -16.622 2.994   1    14.441 ? 1273 TYR A H      1 ? 
ATOM   4363 H HA     . TYR A 1 265 ? 18.59   -19.44  3.476   1    14.918 ? 1273 TYR A HA     1 c 
ATOM   4364 H HB2    . TYR A 1 265 ? 19.376  -17.377 5.583   1    14.874 ? 1273 TYR A HB2    1 c 
ATOM   4365 H HB3    . TYR A 1 265 ? 18.909  -19.054 5.864   1    14.897 ? 1273 TYR A HB3    1 c 
ATOM   4366 H HD1    . TYR A 1 265 ? 21.573  -16.909 4.379   1    14.004 ? 1273 TYR A HD1    1 c 
ATOM   4367 H HD2    . TYR A 1 265 ? 20.552  -20.809 5.8     1    14.636 ? 1273 TYR A HD2    1 c 
ATOM   4368 H HE1    . TYR A 1 265 ? 23.93   -17.571 4.223   1    14.152 ? 1273 TYR A HE1    1 c 
ATOM   4369 H HE2    . TYR A 1 265 ? 22.926  -21.482 5.646   1    14.732 ? 1273 TYR A HE2    1 c 
ATOM   4370 H HH     . TYR A 1 265 ? 25.396  -19.158 4.762   1    15.709 ? 1273 TYR A HH     1 ? 
ATOM   4371 N N      . PHE A 1 266 ? 16.337  -18.619 4.279   1    15.892 ? 1274 PHE A N      1 ? 
ATOM   4372 C CA     . PHE A 1 266 ? 14.994  -18.157 4.59    1    14.729 ? 1274 PHE A CA     1 ? 
ATOM   4373 C C      . PHE A 1 266 ? 14.484  -18.93  5.796   1    15.818 ? 1274 PHE A C      1 ? 
ATOM   4374 O O      . PHE A 1 266 ? 14.549  -20.164 5.822   1    16.897 ? 1274 PHE A O      1 ? 
ATOM   4375 C CB     . PHE A 1 266 ? 14.051  -18.401 3.409   1    13.635 ? 1274 PHE A CB     1 ? 
ATOM   4376 C CG     . PHE A 1 266 ? 14.499  -17.723 2.151   1    13.447 ? 1274 PHE A CG     1 ? 
ATOM   4377 C CD1    . PHE A 1 266 ? 15.406  -18.342 1.304   1    13.551 ? 1274 PHE A CD1    1 ? 
ATOM   4378 C CD2    . PHE A 1 266 ? 14.048  -16.455 1.846   1    13.722 ? 1274 PHE A CD2    1 ? 
ATOM   4379 C CE1    . PHE A 1 266 ? 15.829  -17.708 0.147   1    13.625 ? 1274 PHE A CE1    1 ? 
ATOM   4380 C CE2    . PHE A 1 266 ? 14.466  -15.812 0.695   1    14.549 ? 1274 PHE A CE2    1 ? 
ATOM   4381 C CZ     . PHE A 1 266 ? 15.36   -16.436 -0.154  1    13.983 ? 1274 PHE A CZ     1 ? 
ATOM   4382 H H      . PHE A 1 266 ? 16.512  -19.637 4.235   1    15.473 ? 1274 PHE A H      1 ? 
ATOM   4383 H HA     . PHE A 1 266 ? 15.019  -17.093 4.821   1    14.925 ? 1274 PHE A HA     1 c 
ATOM   4384 H HB2    . PHE A 1 266 ? 13.986  -19.476 3.231   1    13.823 ? 1274 PHE A HB2    1 c 
ATOM   4385 H HB3    . PHE A 1 266 ? 13.056  -18.038 3.675   1    13.823 ? 1274 PHE A HB3    1 c 
ATOM   4386 H HD1    . PHE A 1 266 ? 15.772  -19.335 1.542   1    13.605 ? 1274 PHE A HD1    1 c 
ATOM   4387 H HD2    . PHE A 1 266 ? 13.346  -15.963 2.511   1    13.838 ? 1274 PHE A HD2    1 c 
ATOM   4388 H HE1    . PHE A 1 266 ? 16.531  -18.202 -0.516  1    13.714 ? 1274 PHE A HE1    1 c 
ATOM   4389 H HE2    . PHE A 1 266 ? 14.096  -14.82  0.462   1    14.297 ? 1274 PHE A HE2    1 c 
ATOM   4390 H HZ     . PHE A 1 266 ? 15.69   -15.936 -1.059  1    14.019 ? 1274 PHE A HZ     1 c 
ATOM   4391 N N      . CYS A 1 267 ? 13.946  -18.209 6.778   1    16.569 ? 1275 CYS A N      1 ? 
ATOM   4392 C CA     . CYS A 1 267 ? 13.451  -18.871 7.972   1    16.565 ? 1275 CYS A CA     1 ? 
ATOM   4393 C C      . CYS A 1 267 ? 12.299  -18.067 8.557   1    17.551 ? 1275 CYS A C      1 ? 
ATOM   4394 O O      . CYS A 1 267 ? 12.33   -16.832 8.546   1    16.626 ? 1275 CYS A O      1 ? 
ATOM   4395 C CB     . CYS A 1 267 ? 14.584  -19.03  8.997   1    15.733 ? 1275 CYS A CB     1 ? 
ATOM   4396 S SG     . CYS A 1 267 ? 14.208  -20.128 10.387  1    14.035 ? 1275 CYS A SG     1 ? 
ATOM   4397 H H      . CYS A 1 267 ? 13.964  -17.172 6.741   1    16.537 ? 1275 CYS A H      1 ? 
ATOM   4398 H HA     . CYS A 1 267 ? 13.078  -19.854 7.687   1    16.601 ? 1275 CYS A HA     1 c 
ATOM   4399 H HB2    . CYS A 1 267 ? 15.468  -19.418 8.486   1    15.588 ? 1275 CYS A HB2    1 c 
ATOM   4400 H HB3    . CYS A 1 267 ? 14.837  -18.046 9.396   1    15.594 ? 1275 CYS A HB3    1 c 
ATOM   4401 H HG     . CYS A 1 267 ? 13.816  -21.167 9.647   1    14.915 ? 1275 CYS A HG     1 ? 
ATOM   4402 N N      . GLY A 1 268 ? 11.31   -18.778 9.101   1    18.123 ? 1276 GLY A N      1 ? 
ATOM   4403 C CA     . GLY A 1 268 ? 10.137  -18.166 9.687   1    17.586 ? 1276 GLY A CA     1 ? 
ATOM   4404 C C      . GLY A 1 268 ? 8.887   -18.918 9.269   1    17.653 ? 1276 GLY A C      1 ? 
ATOM   4405 O O      . GLY A 1 268 ? 8.948   -20.042 8.789   1    16.001 ? 1276 GLY A O      1 ? 
ATOM   4406 H H      . GLY A 1 268 ? 11.38   -19.812 9.116   1    18.645 ? 1276 GLY A H      1 ? 
ATOM   4407 H HA2    . GLY A 1 268 ? 10.229  -18.172 10.775  1    17.713 ? 1276 GLY A HA2    1 c 
ATOM   4408 H HA3    . GLY A 1 268 ? 10.07   -17.129 9.353   1    17.678 ? 1276 GLY A HA3    1 c 
ATOM   4409 N N      . LEU A 1 269 ? 7.736   -18.284 9.461   1    21.23  ? 1277 LEU A N      1 ? 
ATOM   4410 C CA     . LEU A 1 269 ? 6.478   -18.901 9.063   1    21.743 ? 1277 LEU A CA     1 ? 
ATOM   4411 C C      . LEU A 1 269 ? 6.406   -19.035 7.547   1    20.11  ? 1277 LEU A C      1 ? 
ATOM   4412 O O      . LEU A 1 269 ? 6.789   -18.126 6.816   1    17.882 ? 1277 LEU A O      1 ? 
ATOM   4413 C CB     . LEU A 1 269 ? 5.302   -18.08  9.596   1    22.179 ? 1277 LEU A CB     1 ? 
ATOM   4414 C CG     . LEU A 1 269 ? 5.181   -18.119 11.123  1    21.116 ? 1277 LEU A CG     1 ? 
ATOM   4415 C CD1    . LEU A 1 269 ? 4.233   -17.09  11.664  1    23.145 ? 1277 LEU A CD1    1 ? 
ATOM   4416 C CD2    . LEU A 1 269 ? 4.773   -19.506 11.571  1    19.235 ? 1277 LEU A CD2    1 ? 
ATOM   4417 H H      . LEU A 1 269 ? 7.744   -17.293 9.752   1    21.531 ? 1277 LEU A H      1 ? 
ATOM   4418 H HA     . LEU A 1 269 ? 6.442   -19.9   9.496   1    21.356 ? 1277 LEU A HA     1 c 
ATOM   4419 H HB2    . LEU A 1 269 ? 5.432   -17.043 9.28    1    21.849 ? 1277 LEU A HB2    1 c 
ATOM   4420 H HB3    . LEU A 1 269 ? 4.38    -18.472 9.161   1    21.849 ? 1277 LEU A HB3    1 c 
ATOM   4421 H HG     . LEU A 1 269 ? 6.168   -17.912 11.542  1    21.299 ? 1277 LEU A HG     1 c 
ATOM   4422 H HD11   . LEU A 1 269 ? 3.236   -17.258 11.25   1    22.552 ? 1277 LEU A HD11   1 c 
ATOM   4423 H HD12   . LEU A 1 269 ? 4.191   -17.168 12.752  1    22.552 ? 1277 LEU A HD12   1 c 
ATOM   4424 H HD13   . LEU A 1 269 ? 4.578   -16.092 11.385  1    22.545 ? 1277 LEU A HD13   1 c 
ATOM   4425 H HD21   . LEU A 1 269 ? 5.478   -20.242 11.184  1    19.818 ? 1277 LEU A HD21   1 c 
ATOM   4426 H HD22   . LEU A 1 269 ? 4.769   -19.549 12.663  1    19.8   ? 1277 LEU A HD22   1 c 
ATOM   4427 H HD23   . LEU A 1 269 ? 3.772   -19.729 11.198  1    19.962 ? 1277 LEU A HD23   1 c 
ATOM   4428 N N      . LYS A 1 270 ? 5.9     -20.181 7.079   1    21.5   ? 1278 LYS A N      1 ? 
ATOM   4429 C CA     . LYS A 1 270 ? 5.968   -20.527 5.663   1    26.435 ? 1278 LYS A CA     1 ? 
ATOM   4430 C C      . LYS A 1 270 ? 5.197   -19.55  4.77    1    24.018 ? 1278 LYS A C      1 ? 
ATOM   4431 O O      . LYS A 1 270 ? 5.48    -19.462 3.572   1    30.06  ? 1278 LYS A O      1 ? 
ATOM   4432 C CB     . LYS A 1 270 ? 5.501   -21.967 5.444   1    28.917 ? 1278 LYS A CB     1 ? 
ATOM   4433 C CG     . LYS A 1 270 ? 4.009   -22.147 5.72    1    37.749 ? 1278 LYS A CG     1 ? 
ATOM   4434 C CD     . LYS A 1 270 ? 3.535   -23.595 5.713   1    45.711 ? 1278 LYS A CD     1 ? 
ATOM   4435 C CE     . LYS A 1 270 ? 2.333   -23.766 6.591   1    54.728 ? 1278 LYS A CE     1 ? 
ATOM   4436 N NZ     . LYS A 1 270 ? 1.933   -25.175 6.614   1    67.817 ? 1278 LYS A NZ     1 ? 
ATOM   4437 H H      . LYS A 1 270 ? 5.682   -20.95  7.727   1    20.845 ? 1278 LYS A H      1 ? 
ATOM   4438 H HA     . LYS A 1 270 ? 7.015   -20.481 5.364   1    25.292 ? 1278 LYS A HA     1 c 
ATOM   4439 H HB2    . LYS A 1 270 ? 5.706   -22.259 4.412   1    30.066 ? 1278 LYS A HB2    1 c 
ATOM   4440 H HB3    . LYS A 1 270 ? 6.064   -22.632 6.102   1    30.066 ? 1278 LYS A HB3    1 c 
ATOM   4441 H HG2    . LYS A 1 270 ? 3.782   -21.707 6.693   1    36.989 ? 1278 LYS A HG2    1 c 
ATOM   4442 H HG3    . LYS A 1 270 ? 3.448   -21.591 4.967   1    37.014 ? 1278 LYS A HG3    1 c 
ATOM   4443 H HD2    . LYS A 1 270 ? 3.281   -23.89  4.693   1    45.637 ? 1278 LYS A HD2    1 c 
ATOM   4444 H HD3    . LYS A 1 270 ? 4.338   -24.242 6.072   1    45.637 ? 1278 LYS A HD3    1 c 
ATOM   4445 H HE2    . LYS A 1 270 ? 2.565   -23.44  7.607   1    55.234 ? 1278 LYS A HE2    1 c 
ATOM   4446 H HE3    . LYS A 1 270 ? 1.506   -23.162 6.212   1    55.234 ? 1278 LYS A HE3    1 c 
ATOM   4447 H HZ1    . LYS A 1 270 ? 1.704   -25.414 7.587   1    68.115 ? 1278 LYS A HZ1    1 ? 
ATOM   4448 H HZ2    . LYS A 1 270 ? 1.115   -25.329 6.031   1    64.439 ? 1278 LYS A HZ2    1 ? 
ATOM   4449 H HZ3    . LYS A 1 270 ? 2.712   -25.769 6.289   1    68.567 ? 1278 LYS A HZ3    1 ? 
ATOM   4450 N N      . GLY A 1 271 ? 4.229   -18.825 5.321   1    25.915 ? 1279 GLY A N      1 ? 
ATOM   4451 C CA     . GLY A 1 271 ? 3.521   -17.808 4.574   1    24.341 ? 1279 GLY A CA     1 ? 
ATOM   4452 C C      . GLY A 1 271 ? 4.407   -16.691 4.035   1    25.112 ? 1279 GLY A C      1 ? 
ATOM   4453 O O      . GLY A 1 271 ? 3.952   -15.916 3.195   1    22.625 ? 1279 GLY A O      1 ? 
ATOM   4454 H H      . GLY A 1 271 ? 3.992   -18.966 6.316   1    26.765 ? 1279 GLY A H      1 ? 
ATOM   4455 H HA2    . GLY A 1 271 ? 3.011   -18.289 3.737   1    24.995 ? 1279 GLY A HA2    1 c 
ATOM   4456 H HA3    . GLY A 1 271 ? 2.752   -17.374 5.217   1    24.827 ? 1279 GLY A HA3    1 c 
ATOM   4457 N N      . MET A 1 272 ? 5.65    -16.588 4.504   1    22.933 ? 1280 MET A N      1 ? 
ATOM   4458 C CA     . MET A 1 272 ? 6.547   -15.564 3.989   1    22.477 ? 1280 MET A CA     1 ? 
ATOM   4459 C C      . MET A 1 272 ? 7.01    -15.869 2.56    1    19.768 ? 1280 MET A C      1 ? 
ATOM   4460 O O      . MET A 1 272 ? 7.418   -14.943 1.847   1    22.666 ? 1280 MET A O      1 ? 
ATOM   4461 C CB     . MET A 1 272 ? 7.782   -15.415 4.889   1    19.568 ? 1280 MET A CB     1 ? 
ATOM   4462 C CG     . MET A 1 272 ? 8.719   -16.628 4.904   1    17.586 ? 1280 MET A CG     1 ? 
ATOM   4463 S SD     . MET A 1 272 ? 10.055  -16.537 6.134   1    16.881 ? 1280 MET A SD     1 ? 
ATOM   4464 C CE     . MET A 1 272 ? 11.277  -15.529 5.277   1    15.245 ? 1280 MET A CE     1 ? 
ATOM   4465 H H      . MET A 1 272 ? 6.009   -17.324 5.124   1    22.176 ? 1280 MET A H      1 ? 
ATOM   4466 H HA     . MET A 1 272 ? 6.002   -14.618 3.975   1    21.53  ? 1280 MET A HA     1 c 
ATOM   4467 H HB2    . MET A 1 272 ? 8.346   -14.541 4.558   1    19.705 ? 1280 MET A HB2    1 c 
ATOM   4468 H HB3    . MET A 1 272 ? 7.443   -15.222 5.909   1    19.705 ? 1280 MET A HB3    1 c 
ATOM   4469 H HG2    . MET A 1 272 ? 8.135   -17.528 5.093   1    17.919 ? 1280 MET A HG2    1 c 
ATOM   4470 H HG3    . MET A 1 272 ? 9.173   -16.735 3.917   1    17.9   ? 1280 MET A HG3    1 c 
ATOM   4471 H HE1    . MET A 1 272 ? 12.15   -15.393 5.918   1    15.628 ? 1280 MET A HE1    1 c 
ATOM   4472 H HE2    . MET A 1 272 ? 11.577  -16.028 4.353   1    15.628 ? 1280 MET A HE2    1 c 
ATOM   4473 H HE3    . MET A 1 272 ? 10.843  -14.555 5.041   1    15.663 ? 1280 MET A HE3    1 c 
ATOM   4474 N N      . MET A 1 273 ? 6.993   -17.14  2.137   1    20.301 ? 1281 MET A N      1 ? 
ATOM   4475 C CA     . MET A 1 273 ? 7.711   -17.56  0.941   1    21.567 ? 1281 MET A CA     1 ? 
ATOM   4476 C C      . MET A 1 273 ? 6.987   -17.147 -0.344  1    24.101 ? 1281 MET A C      1 ? 
ATOM   4477 O O      . MET A 1 273 ? 7.632   -16.651 -1.259  1    24.7   ? 1281 MET A O      1 ? 
ATOM   4478 C CB     . MET A 1 273 ? 7.958   -19.073 0.907   1    20.928 ? 1281 MET A CB     1 ? 
ATOM   4479 C CG     . MET A 1 273 ? 8.992   -19.574 1.927   1    20.847 ? 1281 MET A CG     1 ? 
ATOM   4480 S SD     . MET A 1 273 ? 10.563  -18.688 1.996   1    19.982 ? 1281 MET A SD     1 ? 
ATOM   4481 C CE     . MET A 1 273 ? 11.302  -19.056 0.397   1    18.07  ? 1281 MET A CE     1 ? 
ATOM   4482 H H      . MET A 1 273 ? 6.518   -17.879 2.693   1    21.143 ? 1281 MET A H      1 ? 
ATOM   4483 H HA     . MET A 1 273 ? 8.675   -17.049 0.946   1    21.625 ? 1281 MET A HA     1 c 
ATOM   4484 H HB2    . MET A 1 273 ? 7.011   -19.584 1.089   1    21.113 ? 1281 MET A HB2    1 c 
ATOM   4485 H HB3    . MET A 1 273 ? 8.293   -19.346 -0.096  1    21.061 ? 1281 MET A HB3    1 c 
ATOM   4486 H HG2    . MET A 1 273 ? 8.542   -19.536 2.921   1    20.702 ? 1281 MET A HG2    1 c 
ATOM   4487 H HG3    . MET A 1 273 ? 9.208   -20.622 1.712   0.83 20.702 ? 1281 MET A HG3    1 c 
ATOM   4488 H HE1    . MET A 1 273 ? 12.275  -18.566 0.326   1    18.518 ? 1281 MET A HE1    1 c 
ATOM   4489 H HE2    . MET A 1 273 ? 11.429  -20.136 0.296   0.99 18.518 ? 1281 MET A HE2    1 c 
ATOM   4490 H HE3    . MET A 1 273 ? 10.65   -18.69  -0.398  0.91 18.559 ? 1281 MET A HE3    1 c 
ATOM   4491 N N      . PRO A 1 274 ? 5.651   -17.328 -0.489  1    27.518 ? 1282 PRO A N      1 ? 
ATOM   4492 C CA     . PRO A 1 274 ? 4.984   -16.978 -1.751  1    29.445 ? 1282 PRO A CA     1 ? 
ATOM   4493 C C      . PRO A 1 274 ? 5.358   -15.588 -2.268  1    24.117 ? 1282 PRO A C      1 ? 
ATOM   4494 O O      . PRO A 1 274 ? 5.715   -15.439 -3.434  1    25.579 ? 1282 PRO A O      1 ? 
ATOM   4495 C CB     . PRO A 1 274 ? 3.478   -17.181 -1.454  1    29.542 ? 1282 PRO A CB     1 ? 
ATOM   4496 C CG     . PRO A 1 274 ? 3.497   -18.258 -0.371  1    30.311 ? 1282 PRO A CG     1 ? 
ATOM   4497 C CD     . PRO A 1 274 ? 4.739   -17.977 0.472   1    29.433 ? 1282 PRO A CD     1 ? 
ATOM   4498 H HA     . PRO A 1 274 ? 5.276   -17.712 -2.506  1    28.107 ? 1282 PRO A HA     1 c 
ATOM   4499 H HB2    . PRO A 1 274 ? 3.021   -16.26  -1.087  1    29.685 ? 1282 PRO A HB2    1 c 
ATOM   4500 H HB3    . PRO A 1 274 ? 2.944   -17.525 -2.343  1    29.685 ? 1282 PRO A HB3    1 c 
ATOM   4501 H HG2    . PRO A 1 274 ? 2.598   -18.201 0.244   1    30.314 ? 1282 PRO A HG2    1 c 
ATOM   4502 H HG3    . PRO A 1 274 ? 3.554   -19.252 -0.817  1    30.173 ? 1282 PRO A HG3    1 c 
ATOM   4503 H HD2    . PRO A 1 274 ? 4.512   -17.307 1.302   1    29.033 ? 1282 PRO A HD2    1 c 
ATOM   4504 H HD3    . PRO A 1 274 ? 5.173   -18.898 0.86    1    29.076 ? 1282 PRO A HD3    1 c 
ATOM   4505 N N      . GLY A 1 275 ? 5.302   -14.599 -1.38   1    23.832 ? 1283 GLY A N      1 ? 
ATOM   4506 C CA     . GLY A 1 275 ? 5.587   -13.211 -1.687  1    21.963 ? 1283 GLY A CA     1 ? 
ATOM   4507 C C      . GLY A 1 275 ? 7.055   -12.932 -2.019  1    24.472 ? 1283 GLY A C      1 ? 
ATOM   4508 O O      . GLY A 1 275 ? 7.359   -12.057 -2.836  1    21.332 ? 1283 GLY A O      1 ? 
ATOM   4509 H H      . GLY A 1 275 ? 4.994   -14.827 -0.418  1    26.487 ? 1283 GLY A H      1 ? 
ATOM   4510 N N      . ILE A 1 276 ? 7.955   -13.699 -1.388  1    22.843 ? 1284 ILE A N      1 ? 
ATOM   4511 C CA     . ILE A 1 276 ? 9.368   -13.627 -1.712  1    24.739 ? 1284 ILE A CA     1 ? 
ATOM   4512 C C      . ILE A 1 276 ? 9.592   -14.174 -3.124  1    20.188 ? 1284 ILE A C      1 ? 
ATOM   4513 O O      . ILE A 1 276 ? 10.273  -13.519 -3.925  1    21.6   ? 1284 ILE A O      1 ? 
ATOM   4514 C CB     . ILE A 1 276 ? 10.202  -14.354 -0.629  1    25.76  ? 1284 ILE A CB     1 ? 
ATOM   4515 C CG1    . ILE A 1 276 ? 10.23   -13.531 0.674   0.99 27.565 ? 1284 ILE A CG1    1 ? 
ATOM   4516 C CG2    . ILE A 1 276 ? 11.606  -14.704 -1.104  1    22.727 ? 1284 ILE A CG2    1 ? 
ATOM   4517 C CD1    . ILE A 1 276 ? 10.798  -14.29  1.853   0.95 30.692 ? 1284 ILE A CD1    1 ? 
ATOM   4518 H H      . ILE A 1 276 ? 7.625   -14.408 -0.7    1    24.837 ? 1284 ILE A H      1 ? 
ATOM   4519 H HA     . ILE A 1 276 ? 9.66    -12.58  -1.712  1    23.564 ? 1284 ILE A HA     1 c 
ATOM   4520 H HB     . ILE A 1 276 ? 9.691   -15.292 -0.405  0.89 25.3   ? 1284 ILE A HB     1 c 
ATOM   4521 H HG12   . ILE A 1 276 ? 10.828  -12.632 0.511   0.34 27.801 ? 1284 ILE A HG12   1 c 
ATOM   4522 H HG13   . ILE A 1 276 ? 9.211   -13.217 0.914   1    27.739 ? 1284 ILE A HG13   1 c 
ATOM   4523 H HG21   . ILE A 1 276 ? 12.135  -13.792 -1.39   0.86 23.512 ? 1284 ILE A HG21   1 c 
ATOM   4524 H HG22   . ILE A 1 276 ? 12.15   -15.201 -0.301  0.9  23.445 ? 1284 ILE A HG22   1 c 
ATOM   4525 H HG23   . ILE A 1 276 ? 11.547  -15.374 -1.965  0.98 23.52  ? 1284 ILE A HG23   1 c 
ATOM   4526 H HD11   . ILE A 1 276 ? 10.229  -15.209 2.006   0.87 29.716 ? 1284 ILE A HD11   1 c 
ATOM   4527 H HD12   . ILE A 1 276 ? 11.844  -14.54  1.661   1    29.637 ? 1284 ILE A HD12   1 c 
ATOM   4528 H HD13   . ILE A 1 276 ? 10.735  -13.67  2.75    1    29.581 ? 1284 ILE A HD13   1 c 
ATOM   4529 N N      . GLN A 1 277 ? 9.016   -15.348 -3.438  1    20.217 ? 1285 GLN A N      1 ? 
ATOM   4530 C CA     . GLN A 1 277 ? 9.156   -15.91  -4.769  1    23.886 ? 1285 GLN A CA     1 ? 
ATOM   4531 C C      . GLN A 1 277 ? 8.593   -14.969 -5.84   1    25.291 ? 1285 GLN A C      1 ? 
ATOM   4532 O O      . GLN A 1 277 ? 9.197   -14.803 -6.902  1    28.755 ? 1285 GLN A O      1 ? 
ATOM   4533 C CB     . GLN A 1 277 ? 8.472   -17.276 -4.87   1    22.767 ? 1285 GLN A CB     1 ? 
ATOM   4534 C CG     . GLN A 1 277 ? 9.084   -18.375 -4.015  1    23.15  ? 1285 GLN A CG     1 ? 
ATOM   4535 C CD     . GLN A 1 277 ? 10.398  -18.91  -4.554  1    25.168 ? 1285 GLN A CD     1 ? 
ATOM   4536 O OE1    . GLN A 1 277 ? 10.846  -18.569 -5.656  1    27.08  ? 1285 GLN A OE1    1 ? 
ATOM   4537 N NE2    . GLN A 1 277 ? 11.022  -19.785 -3.772  1    22.688 ? 1285 GLN A NE2    1 ? 
ATOM   4538 H H      . GLN A 1 277 ? 8.392   -15.811 -2.756  1    21.95  ? 1285 GLN A H      1 ? 
ATOM   4539 H HA     . GLN A 1 277 ? 10.221  -16.05  -4.964  1    23.177 ? 1285 GLN A HA     1 c 
ATOM   4540 H HB2    . GLN A 1 277 ? 7.427   -17.155 -4.581  1    23.175 ? 1285 GLN A HB2    1 c 
ATOM   4541 H HB3    . GLN A 1 277 ? 8.486   -17.593 -5.914  1    23.209 ? 1285 GLN A HB3    1 c 
ATOM   4542 H HG2    . GLN A 1 277 ? 9.253   -17.991 -3.007  1    23.494 ? 1285 GLN A HG2    1 c 
ATOM   4543 H HG3    . GLN A 1 277 ? 8.377   -19.203 -3.938  1    23.494 ? 1285 GLN A HG3    1 c 
ATOM   4544 H HE21   . GLN A 1 277 ? 10.542  -20.105 -2.942  1    22.705 ? 1285 GLN A HE21   1 ? 
ATOM   4545 H HE22   . GLN A 1 277 ? 11.951  -20.122 -4.024  1    20.759 ? 1285 GLN A HE22   1 ? 
ATOM   4546 N N      . ASP A 1 278 ? 7.453   -14.337 -5.562  1    26.279 ? 1286 ASP A N      1 ? 
ATOM   4547 C CA     . ASP A 1 278 ? 6.854   -13.389 -6.496  1    27.361 ? 1286 ASP A CA     1 ? 
ATOM   4548 C C      . ASP A 1 278 ? 7.812   -12.229 -6.788  1    24.686 ? 1286 ASP A C      1 ? 
ATOM   4549 O O      . ASP A 1 278 ? 8.02    -11.833 -7.942  1    25.406 ? 1286 ASP A O      1 ? 
ATOM   4550 C CB     . ASP A 1 278 ? 5.503   -12.946 -5.964  1    32.501 ? 1286 ASP A CB     1 ? 
ATOM   4551 C CG     . ASP A 1 278 ? 4.637   -12.152 -6.931  1    36.609 ? 1286 ASP A CG     1 ? 
ATOM   4552 O OD1    . ASP A 1 278 ? 4.043   -12.794 -7.846  1    33.27  ? 1286 ASP A OD1    1 ? 
ATOM   4553 O OD2    . ASP A 1 278 ? 4.576   -10.906 -6.767  1    31.844 ? 1286 ASP A OD2    1 ? 
ATOM   4554 H H      . ASP A 1 278 ? 6.97    -14.517 -4.666  1    27.553 ? 1286 ASP A H      1 ? 
ATOM   4555 H HA     . ASP A 1 278 ? 6.668   -13.915 -7.434  1    27.519 ? 1286 ASP A HA     1 c 
ATOM   4556 H HB2    . ASP A 1 278 ? 4.942   -13.833 -5.661  1    32.124 ? 1286 ASP A HB2    1 c 
ATOM   4557 H HB3    . ASP A 1 278 ? 5.664   -12.334 -5.075  1    32.124 ? 1286 ASP A HB3    1 c 
ATOM   4558 N N      . THR A 1 279 ? 8.389   -11.655 -5.729  1    23.517 ? 1287 THR A N      1 ? 
ATOM   4559 C CA     . THR A 1 279 ? 9.317   -10.551 -5.89   1    22.243 ? 1287 THR A CA     1 ? 
ATOM   4560 C C      . THR A 1 279 ? 10.558  -10.975 -6.668  1    20.675 ? 1287 THR A C      1 ? 
ATOM   4561 O O      . THR A 1 279 ? 11.001  -10.273 -7.584  1    21.143 ? 1287 THR A O      1 ? 
ATOM   4562 C CB     . THR A 1 279 ? 9.699   -9.969  -4.536  1    22.818 ? 1287 THR A CB     1 ? 
ATOM   4563 O OG1    . THR A 1 279 ? 8.587   -9.239  -4      1    24.546 ? 1287 THR A OG1    1 ? 
ATOM   4564 C CG2    . THR A 1 279 ? 10.879  -9.023  -4.665  1    22.985 ? 1287 THR A CG2    1 ? 
ATOM   4565 H H      . THR A 1 279 ? 8.153   -11.971 -4.773  1    27.26  ? 1287 THR A H      1 ? 
ATOM   4566 H HA     . THR A 1 279 ? 8.809   -9.77   -6.46   1    22.291 ? 1287 THR A HA     1 c 
ATOM   4567 H HB     . THR A 1 279 ? 9.963   -10.779 -3.854  1    23.013 ? 1287 THR A HB     1 c 
ATOM   4568 H HG1    . THR A 1 279 ? 8.854   -8.368  -3.631  1    23.113 ? 1287 THR A HG1    1 ? 
ATOM   4569 H HG21   . THR A 1 279 ? 11.009  -8.477  -3.73   1    22.875 ? 1287 THR A HG21   1 c 
ATOM   4570 H HG22   . THR A 1 279 ? 11.786  -9.592  -4.88   1    22.906 ? 1287 THR A HG22   1 c 
ATOM   4571 H HG23   . THR A 1 279 ? 10.691  -8.314  -5.474  1    22.901 ? 1287 THR A HG23   1 c 
ATOM   4572 N N      . LEU A 1 280 ? 11.126  -12.13  -6.323  1    21.442 ? 1288 LEU A N      1 ? 
ATOM   4573 C CA     . LEU A 1 280 ? 12.33   -12.582 -7.013  1    22.003 ? 1288 LEU A CA     1 ? 
ATOM   4574 C C      . LEU A 1 280 ? 12.064  -12.841 -8.488  1    20.492 ? 1288 LEU A C      1 ? 
ATOM   4575 O O      . LEU A 1 280 ? 12.901  -12.527 -9.338  1    22.155 ? 1288 LEU A O      1 ? 
ATOM   4576 C CB     . LEU A 1 280 ? 12.919  -13.814 -6.316  1    20.277 ? 1288 LEU A CB     1 ? 
ATOM   4577 C CG     . LEU A 1 280 ? 13.452  -13.509 -4.915  1    20.571 ? 1288 LEU A CG     1 ? 
ATOM   4578 C CD1    . LEU A 1 280 ? 13.761  -14.784 -4.162  1    22.628 ? 1288 LEU A CD1    1 ? 
ATOM   4579 C CD2    . LEU A 1 280 ? 14.702  -12.661 -5.033  1    20.579 ? 1288 LEU A CD2    1 ? 
ATOM   4580 H H      . LEU A 1 280 ? 10.729  -12.708 -5.564  1    21.218 ? 1288 LEU A H      1 ? 
ATOM   4581 H HA     . LEU A 1 280 ? 13.06   -11.772 -6.955  1    21.298 ? 1288 LEU A HA     1 c 
ATOM   4582 H HB2    . LEU A 1 280 ? 12.14   -14.575 -6.238  1    20.706 ? 1288 LEU A HB2    1 c 
ATOM   4583 H HB3    . LEU A 1 280 ? 13.738  -14.201 -6.927  1    20.706 ? 1288 LEU A HB3    1 c 
ATOM   4584 H HG     . LEU A 1 280 ? 12.694  -12.947 -4.366  1    20.882 ? 1288 LEU A HG     1 c 
ATOM   4585 H HD11   . LEU A 1 280 ? 14.039  -14.543 -3.134  1    22.014 ? 1288 LEU A HD11   1 c 
ATOM   4586 H HD12   . LEU A 1 280 ? 12.88   -15.429 -4.158  1    22.014 ? 1288 LEU A HD12   1 c 
ATOM   4587 H HD13   . LEU A 1 280 ? 14.588  -15.304 -4.648  1    21.954 ? 1288 LEU A HD13   1 c 
ATOM   4588 H HD21   . LEU A 1 280 ? 15.131  -12.503 -4.042  1    20.578 ? 1288 LEU A HD21   1 c 
ATOM   4589 H HD22   . LEU A 1 280 ? 15.431  -13.172 -5.666  1    20.578 ? 1288 LEU A HD22   1 c 
ATOM   4590 H HD23   . LEU A 1 280 ? 14.451  -11.696 -5.477  1    20.582 ? 1288 LEU A HD23   1 c 
ATOM   4591 N N      . LYS A 1 281 ? 10.889  -13.383 -8.811  1    24.039 ? 1289 LYS A N      1 ? 
ATOM   4592 C CA     . LYS A 1 281 ? 10.526  -13.581 -10.211 1    26.951 ? 1289 LYS A CA     1 ? 
ATOM   4593 C C      . LYS A 1 281 ? 10.464  -12.246 -10.955 1    23.282 ? 1289 LYS A C      1 ? 
ATOM   4594 O O      . LYS A 1 281 ? 10.976  -12.125 -12.079 1    27.417 ? 1289 LYS A O      1 ? 
ATOM   4595 C CB     . LYS A 1 281 ? 9.19    -14.31  -10.295 1    31.558 ? 1289 LYS A CB     1 ? 
ATOM   4596 C CG     . LYS A 1 281 ? 8.764   -14.705 -11.693 1    46.075 ? 1289 LYS A CG     1 ? 
ATOM   4597 C CD     . LYS A 1 281 ? 7.272   -14.942 -11.869 1    53.952 ? 1289 LYS A CD     1 ? 
ATOM   4598 C CE     . LYS A 1 281 ? 6.995   -15.419 -13.251 1    72.749 ? 1289 LYS A CE     1 ? 
ATOM   4599 N NZ     . LYS A 1 281 ? 5.605   -15.868 -13.361 1    89.212 ? 1289 LYS A NZ     1 ? 
ATOM   4600 H H      . LYS A 1 281 ? 10.24   -13.702 -8.068  1    24.417 ? 1289 LYS A H      1 ? 
ATOM   4601 H HA     . LYS A 1 281 ? 11.291  -14.2   -10.678 1    26.357 ? 1289 LYS A HA     1 c 
ATOM   4602 H HB2    . LYS A 1 281 ? 9.246   -15.213 -9.684  1    33.174 ? 1289 LYS A HB2    1 c 
ATOM   4603 H HB3    . LYS A 1 281 ? 8.416   -13.669 -9.868  1    33.174 ? 1289 LYS A HB3    1 c 
ATOM   4604 H HG2    . LYS A 1 281 ? 9.078   -13.922 -12.385 1    43.668 ? 1289 LYS A HG2    1 c 
ATOM   4605 H HG3    . LYS A 1 281 ? 9.298   -15.617 -11.968 1    43.793 ? 1289 LYS A HG3    1 c 
ATOM   4606 H HD2    . LYS A 1 281 ? 6.932   -15.691 -11.151 1    55.753 ? 1289 LYS A HD2    1 c 
ATOM   4607 H HD3    . LYS A 1 281 ? 6.729   -14.011 -11.691 1    55.753 ? 1289 LYS A HD3    1 c 
ATOM   4608 H HE2    . LYS A 1 281 ? 7.168   -14.614 -13.966 1    71.132 ? 1289 LYS A HE2    1 c 
ATOM   4609 H HE3    . LYS A 1 281 ? 7.661   -16.249 -13.496 1    71.272 ? 1289 LYS A HE3    1 c 
ATOM   4610 H HZ1    A LYS A 1 281 ? 4.985   -15.142 -12.995 0.5  91.13  ? 1289 LYS A HZ1    1 ? 
ATOM   4611 H HZ1    D LYS A 1 281 ? 5.393   -16.045 -14.345 0.5  91.205 ? 1289 LYS A HZ1    1 ? 
ATOM   4612 H HZ2    A LYS A 1 281 ? 5.387   -16.046 -14.344 0.5  91.25  ? 1289 LYS A HZ2    1 ? 
ATOM   4613 H HZ2    D LYS A 1 281 ? 5.467   -16.724 -12.822 0.5  89.804 ? 1289 LYS A HZ2    1 ? 
ATOM   4614 H HZ3    A LYS A 1 281 ? 5.467   -16.72  -12.815 0.5  88.77  ? 1289 LYS A HZ3    1 ? 
ATOM   4615 H HZ3    D LYS A 1 281 ? 4.982   -15.14  -13.003 0.5  89.995 ? 1289 LYS A HZ3    1 ? 
ATOM   4616 N N      . LYS A 1 282 ? 9.847   -11.233 -10.338 1    24.926 ? 1290 LYS A N      1 ? 
ATOM   4617 C CA     . LYS A 1 282 ? 9.711   -9.934  -10.979 1    25.717 ? 1290 LYS A CA     1 ? 
ATOM   4618 C C      . LYS A 1 282 ? 11.059  -9.231  -11.116 1    27.261 ? 1290 LYS A C      1 ? 
ATOM   4619 O O      . LYS A 1 282 ? 11.341  -8.617  -12.151 1    26.625 ? 1290 LYS A O      1 ? 
ATOM   4620 C CB     . LYS A 1 282 ? 8.707   -9.084  -10.2   1    29.34  ? 1290 LYS A CB     1 ? 
ATOM   4621 C CG     . LYS A 1 282 ? 7.297   -9.626  -10.422 1    34.981 ? 1290 LYS A CG     1 ? 
ATOM   4622 C CD     . LYS A 1 282 ? 6.172   -8.875  -9.733  1    39.531 ? 1290 LYS A CD     1 ? 
ATOM   4623 C CE     . LYS A 1 282 ? 4.918   -9.717  -9.782  1    48.121 ? 1290 LYS A CE     1 ? 
ATOM   4624 N NZ     . LYS A 1 282 ? 4.066   -9.45   -8.611  1    50.217 ? 1290 LYS A NZ     1 ? 
ATOM   4625 H H      . LYS A 1 282 ? 9.389   -11.378 -9.422  1    24.514 ? 1290 LYS A H      1 ? 
ATOM   4626 H HA     . LYS A 1 282 ? 9.31    -10.096 -11.982 1    26.444 ? 1290 LYS A HA     1 c 
ATOM   4627 H HB2    . LYS A 1 282 ? 8.942   -9.113  -9.134  1    29.631 ? 1290 LYS A HB2    1 c 
ATOM   4628 H HB3    . LYS A 1 282 ? 8.753   -8.047  -10.539 1    29.631 ? 1290 LYS A HB3    1 c 
ATOM   4629 H HG2    . LYS A 1 282 ? 7.102   -9.631  -11.496 1    34.575 ? 1290 LYS A HG2    1 c 
ATOM   4630 H HG3    . LYS A 1 282 ? 7.277   -10.665 -10.087 1    34.594 ? 1290 LYS A HG3    1 c 
ATOM   4631 H HD2    . LYS A 1 282 ? 6.44    -8.68   -8.692  1    40.193 ? 1290 LYS A HD2    1 c 
ATOM   4632 H HD3    . LYS A 1 282 ? 5.995   -7.925  -10.241 1    40.193 ? 1290 LYS A HD3    1 c 
ATOM   4633 H HE2    . LYS A 1 282 ? 4.357   -9.488  -10.692 1    46.514 ? 1290 LYS A HE2    1 c 
ATOM   4634 H HE3    . LYS A 1 282 ? 5.182   -10.776 -9.799  1    46.359 ? 1290 LYS A HE3    1 c 
ATOM   4635 H HZ1    . LYS A 1 282 ? 3.241   -10.065 -8.646  1    46.252 ? 1290 LYS A HZ1    1 ? 
ATOM   4636 H HZ2    . LYS A 1 282 ? 4.593   -9.643  -7.76   1    46.599 ? 1290 LYS A HZ2    1 ? 
ATOM   4637 H HZ3    . LYS A 1 282 ? 3.794   -8.463  -8.593  1    46.174 ? 1290 LYS A HZ3    1 ? 
ATOM   4638 N N      . VAL A 1 283 ? 11.907  -9.324  -10.088 1    24.51  ? 1291 VAL A N      1 ? 
ATOM   4639 C CA     . VAL A 1 283 ? 13.241  -8.744  -10.175 1    22.692 ? 1291 VAL A CA     1 ? 
ATOM   4640 C C      . VAL A 1 283 ? 14.024  -9.384  -11.318 1    22.754 ? 1291 VAL A C      1 ? 
ATOM   4641 O O      . VAL A 1 283 ? 14.65   -8.694  -12.13  1    22.432 ? 1291 VAL A O      1 ? 
ATOM   4642 C CB     . VAL A 1 283 ? 13.984  -8.903  -8.838  1    22.534 ? 1291 VAL A CB     1 ? 
ATOM   4643 C CG1    . VAL A 1 283 ? 15.462  -8.605  -9.033  1    21.392 ? 1291 VAL A CG1    1 ? 
ATOM   4644 C CG2    . VAL A 1 283 ? 13.382  -8.008  -7.767  1    22.766 ? 1291 VAL A CG2    1 ? 
ATOM   4645 H H      . VAL A 1 283 ? 11.673  -9.928  -9.277  1    23.862 ? 1291 VAL A H      1 ? 
ATOM   4646 H HA     . VAL A 1 283 ? 13.135  -7.678  -10.384 1    23.008 ? 1291 VAL A HA     1 c 
ATOM   4647 H HB     . VAL A 1 283 ? 13.877  -9.943  -8.523  1    22.394 ? 1291 VAL A HB     1 c 
ATOM   4648 H HG11   . VAL A 1 283 ? 15.578  -7.634  -9.518  1    21.819 ? 1291 VAL A HG11   1 c 
ATOM   4649 H HG12   . VAL A 1 283 ? 15.961  -8.585  -8.062  1    21.737 ? 1291 VAL A HG12   1 c 
ATOM   4650 H HG13   . VAL A 1 283 ? 15.915  -9.378  -9.657  1    21.761 ? 1291 VAL A HG13   1 c 
ATOM   4651 H HG21   . VAL A 1 283 ? 13.884  -8.191  -6.815  1    22.699 ? 1291 VAL A HG21   1 c 
ATOM   4652 H HG22   . VAL A 1 283 ? 13.513  -6.961  -8.051  1    22.699 ? 1291 VAL A HG22   1 c 
ATOM   4653 H HG23   . VAL A 1 283 ? 12.318  -8.225  -7.664  1    22.691 ? 1291 VAL A HG23   1 c 
ATOM   4654 N N      . ALA A 1 284 ? 13.993  -10.718 -11.392 1    20.111 ? 1292 ALA A N      1 ? 
ATOM   4655 C CA     . ALA A 1 284 ? 14.685  -11.416 -12.465 1    21.421 ? 1292 ALA A CA     1 ? 
ATOM   4656 C C      . ALA A 1 284 ? 14.174  -10.959 -13.83  1    20.015 ? 1292 ALA A C      1 ? 
ATOM   4657 O O      . ALA A 1 284 ? 14.971  -10.664 -14.736 1    17.018 ? 1292 ALA A O      1 ? 
ATOM   4658 C CB     . ALA A 1 284 ? 14.529  -12.922 -12.302 1    19.038 ? 1292 ALA A CB     1 ? 
ATOM   4659 H H      . ALA A 1 284 ? 13.432  -11.269 -10.713 1    20.083 ? 1292 ALA A H      1 ? 
ATOM   4660 H HA     . ALA A 1 284 ? 15.746  -11.164 -12.401 1    20.481 ? 1292 ALA A HA     1 c 
ATOM   4661 H HB1    . ALA A 1 284 ? 15.051  -13.436 -13.111 1    19.675 ? 1292 ALA A HB1    1 c 
ATOM   4662 H HB2    . ALA A 1 284 ? 14.952  -13.234 -11.344 1    19.675 ? 1292 ALA A HB2    1 c 
ATOM   4663 H HB3    . ALA A 1 284 ? 13.47   -13.187 -12.331 1    19.684 ? 1292 ALA A HB3    1 c 
ATOM   4664 N N      . GLU A 1 285 ? 12.842  -10.882 -13.986 1    20.826 ? 1293 GLU A N      1 ? 
ATOM   4665 C CA     . GLU A 1 285 ? 12.249  -10.477 -15.274 1    26.738 ? 1293 GLU A CA     1 ? 
ATOM   4666 C C      . GLU A 1 285 ? 12.751  -9.076  -15.665 1    25.307 ? 1293 GLU A C      1 ? 
ATOM   4667 O O      . GLU A 1 285 ? 13.068  -8.828  -16.833 1    21.593 ? 1293 GLU A O      1 ? 
ATOM   4668 C CB     . GLU A 1 285 ? 10.737  -10.293 -15.493 1    31.028 ? 1293 GLU A CB     1 ? 
ATOM   4669 C CG     . GLU A 1 285 ? 9.82    -11.163 -14.627 1    47.028 ? 1293 GLU A CG     1 ? 
ATOM   4670 C CD     . GLU A 1 285 ? 9.04    -12.333 -15.244 1    55.346 ? 1293 GLU A CD     1 ? 
ATOM   4671 O OE1    . GLU A 1 285 ? 9.614   -13.075 -16.103 1    58.68  ? 1293 GLU A OE1    1 ? 
ATOM   4672 O OE2    . GLU A 1 285 ? 7.856   -12.533 -14.835 1    49.585 ? 1293 GLU A OE2    1 ? 
ATOM   4673 H HA     . GLU A 1 285 ? 12.6    -11.181 -16.031 1    25.942 ? 1293 GLU A HA     1 c 
ATOM   4674 H HB2    . GLU A 1 285 ? 10.482  -9.249  -15.305 1    32.99  ? 1293 GLU A HB2    1 c 
ATOM   4675 H HB3    . GLU A 1 285 ? 10.512  -10.503 -16.54  1    32.955 ? 1293 GLU A HB3    1 c 
ATOM   4676 H HG2    . GLU A 1 285 ? 10.422  -11.573 -13.82  1    44.019 ? 1293 GLU A HG2    1 c 
ATOM   4677 H HG3    . GLU A 1 285 ? 9.091   -10.505 -14.149 1    44.357 ? 1293 GLU A HG3    1 c 
ATOM   4678 N N      . ARG A 1 286 ? 12.795  -8.151  -14.706 1    24.36  ? 1294 ARG A N      1 ? 
ATOM   4679 C CA     . ARG A 1 286 ? 13.246  -6.793  -15.01  1    25.309 ? 1294 ARG A CA     1 ? 
ATOM   4680 C C      . ARG A 1 286 ? 14.694  -6.782  -15.48  1    21.659 ? 1294 ARG A C      1 ? 
ATOM   4681 O O      . ARG A 1 286 ? 15.079  -5.921  -16.275 1    22.831 ? 1294 ARG A O      1 ? 
ATOM   4682 C CB     . ARG A 1 286 ? 13.105  -5.908  -13.772 1    28.317 ? 1294 ARG A CB     1 ? 
ATOM   4683 C CG     . ARG A 1 286 ? 11.66   -5.532  -13.49  1    33.476 ? 1294 ARG A CG     1 ? 
ATOM   4684 C CD     . ARG A 1 286 ? 11.571  -4.575  -12.31  1    36.954 ? 1294 ARG A CD     1 ? 
ATOM   4685 N NE     . ARG A 1 286 ? 10.278  -4.699  -11.626 1    42.919 ? 1294 ARG A NE     1 ? 
ATOM   4686 C CZ     . ARG A 1 286 ? 10.092  -4.801  -10.308 1    45.967 ? 1294 ARG A CZ     1 ? 
ATOM   4687 N NH1    . ARG A 1 286 ? 11.11   -4.993  -9.485  1    43.228 ? 1294 ARG A NH1    1 ? 
ATOM   4688 N NH2    . ARG A 1 286 ? 8.867   -4.719  -9.819  1    42.11  ? 1294 ARG A NH2    1 ? 
ATOM   4689 H H      . ARG A 1 286 ? 12.484  -8.397  -13.758 1    22.565 ? 1294 ARG A H      1 ? 
ATOM   4690 H HA     . ARG A 1 286 ? 12.616  -6.393  -15.807 1    24.929 ? 1294 ARG A HA     1 c 
ATOM   4691 H HB2    . ARG A 1 286 ? 13.512  -6.435  -12.907 1    28.666 ? 1294 ARG A HB2    1 c 
ATOM   4692 H HB3    . ARG A 1 286 ? 13.689  -4.996  -13.916 1    28.666 ? 1294 ARG A HB3    1 c 
ATOM   4693 H HG2    . ARG A 1 286 ? 11.226  -5.058  -14.372 1    33.016 ? 1294 ARG A HG2    1 c 
ATOM   4694 H HG3    . ARG A 1 286 ? 11.089  -6.432  -13.264 1    33.167 ? 1294 ARG A HG3    1 c 
ATOM   4695 H HD2    . ARG A 1 286 ? 12.38   -4.791  -11.611 1    37.499 ? 1294 ARG A HD2    1 c 
ATOM   4696 H HD3    . ARG A 1 286 ? 11.695  -3.549  -12.665 1    37.434 ? 1294 ARG A HD3    1 c 
ATOM   4697 H HE     . ARG A 1 286 ? 9.443   -4.73   -12.204 1    42.007 ? 1294 ARG A HE     1 ? 
ATOM   4698 H HH11   . ARG A 1 286 ? 12.056  -5.069  -9.829  1    43.678 ? 1294 ARG A HH11   1 ? 
ATOM   4699 H HH12   . ARG A 1 286 ? 10.93   -5.068  -8.501  1    43.924 ? 1294 ARG A HH12   1 ? 
ATOM   4700 H HH21   . ARG A 1 286 ? 8.088   -4.599  -10.454 1    43.558 ? 1294 ARG A HH21   1 ? 
ATOM   4701 H HH22   . ARG A 1 286 ? 8.716   -4.769  -8.819  1    43.713 ? 1294 ARG A HH22   1 ? 
ATOM   4702 N N      . ARG A 1 287 ? 15.499  -7.72   -14.99  1    19.733 ? 1295 ARG A N      1 ? 
ATOM   4703 C CA     . ARG A 1 287 ? 16.89   -7.849  -15.403 1    20.124 ? 1295 ARG A CA     1 ? 
ATOM   4704 C C      . ARG A 1 287 ? 17.043  -8.664  -16.681 1    19.234 ? 1295 ARG A C      1 ? 
ATOM   4705 O O      . ARG A 1 287 ? 18.167  -8.81   -17.168 1    20.13  ? 1295 ARG A O      1 ? 
ATOM   4706 C CB     . ARG A 1 287 ? 17.711  -8.516  -14.288 1    20.923 ? 1295 ARG A CB     1 ? 
ATOM   4707 C CG     . ARG A 1 287 ? 17.727  -7.748  -12.974 1    21.962 ? 1295 ARG A CG     1 ? 
ATOM   4708 C CD     . ARG A 1 287 ? 18.298  -8.604  -11.83  1    22.693 ? 1295 ARG A CD     1 ? 
ATOM   4709 N NE     . ARG A 1 287 ? 19.697  -8.979  -12.045 1    22.899 ? 1295 ARG A NE     1 ? 
ATOM   4710 C CZ     . ARG A 1 287 ? 20.727  -8.193  -11.795 1    23.022 ? 1295 ARG A CZ     1 ? 
ATOM   4711 N NH1    . ARG A 1 287 ? 20.571  -6.967  -11.355 1    24.288 ? 1295 ARG A NH1    1 ? 
ATOM   4712 N NH2    . ARG A 1 287 ? 21.96   -8.625  -11.991 1    24.95  ? 1295 ARG A NH2    1 ? 
ATOM   4713 H H      . ARG A 1 287 ? 15.081  -8.433  -14.367 1    21.554 ? 1295 ARG A H      1 ? 
ATOM   4714 H HA     . ARG A 1 287 ? 17.29   -6.849  -15.579 1    20.041 ? 1295 ARG A HA     1 c 
ATOM   4715 H HB2    . ARG A 1 287 ? 17.305  -9.513  -14.105 1    20.983 ? 1295 ARG A HB2    1 c 
ATOM   4716 H HB3    . ARG A 1 287 ? 18.739  -8.636  -14.634 1    21.04  ? 1295 ARG A HB3    1 c 
ATOM   4717 H HG2    . ARG A 1 287 ? 18.338  -6.849  -13.087 1    21.894 ? 1295 ARG A HG2    1 c 
ATOM   4718 H HG3    . ARG A 1 287 ? 16.712  -7.44   -12.72  1    21.928 ? 1295 ARG A HG3    1 c 
ATOM   4719 H HD2    . ARG A 1 287 ? 18.216  -8.048  -10.893 1    22.602 ? 1295 ARG A HD2    1 c 
ATOM   4720 H HD3    . ARG A 1 287 ? 17.696  -9.51   -11.733 1    22.585 ? 1295 ARG A HD3    1 c 
ATOM   4721 H HE     . ARG A 1 287 ? 19.953  -9.862  -12.468 1    23.481 ? 1295 ARG A HE     1 ? 
ATOM   4722 H HH11   . ARG A 1 287 ? 19.65   -6.546  -11.205 1    24.074 ? 1295 ARG A HH11   1 ? 
ATOM   4723 H HH12   . ARG A 1 287 ? 21.41   -6.441  -11.169 1    24.908 ? 1295 ARG A HH12   1 ? 
ATOM   4724 H HH21   . ARG A 1 287 ? 22.14   -9.585  -12.281 1    23.974 ? 1295 ARG A HH21   1 ? 
ATOM   4725 H HH22   . ARG A 1 287 ? 22.736  -8.027  -11.735 1    23.96  ? 1295 ARG A HH22   1 ? 
ATOM   4726 N N      . GLY A 1 288 ? 15.955  -9.209  -17.214 1    20.367 ? 1296 GLY A N      1 ? 
ATOM   4727 C CA     . GLY A 1 288 ? 16.046  -10.056 -18.386 1    19.686 ? 1296 GLY A CA     1 ? 
ATOM   4728 C C      . GLY A 1 288 ? 16.5    -11.482 -18.081 1    19.932 ? 1296 GLY A C      1 ? 
ATOM   4729 O O      . GLY A 1 288 ? 17.036  -12.153 -18.967 1    18.597 ? 1296 GLY A O      1 ? 
ATOM   4730 H H      . GLY A 1 288 ? 15.028  -9.056  -16.779 1    19.246 ? 1296 GLY A H      1 ? 
ATOM   4731 H HA2    . GLY A 1 288 ? 15.071  -10.086 -18.876 1    19.885 ? 1296 GLY A HA2    1 c 
ATOM   4732 H HA3    . GLY A 1 288 ? 16.754  -9.6    -19.08  1    19.851 ? 1296 GLY A HA3    1 c 
ATOM   4733 N N      . GLU A 1 289 ? 16.288  -11.938 -16.854 1    20.964 ? 1297 GLU A N      1 ? 
ATOM   4734 C CA     . GLU A 1 289 ? 16.677  -13.282 -16.45  1    21.285 ? 1297 GLU A CA     1 ? 
ATOM   4735 C C      . GLU A 1 289 ? 15.426  -14.098 -16.105 1    18.644 ? 1297 GLU A C      1 ? 
ATOM   4736 O O      . GLU A 1 289 ? 14.373  -13.561 -15.798 1    20.258 ? 1297 GLU A O      1 ? 
ATOM   4737 C CB     . GLU A 1 289 ? 17.59   -13.299 -15.219 1    22.901 ? 1297 GLU A CB     1 ? 
ATOM   4738 C CG     . GLU A 1 289 ? 18.83   -12.423 -15.361 1    26.319 ? 1297 GLU A CG     1 ? 
ATOM   4739 C CD     . GLU A 1 289 ? 19.676  -12.553 -14.104 1    26.702 ? 1297 GLU A CD     1 ? 
ATOM   4740 O OE1    . GLU A 1 289 ? 20.045  -13.704 -13.748 1    29.634 ? 1297 GLU A OE1    1 ? 
ATOM   4741 O OE2    . GLU A 1 289 ? 19.921  -11.526 -13.456 1    28.385 ? 1297 GLU A OE2    1 ? 
ATOM   4742 H H      . GLU A 1 289 ? 15.678  -11.398 -16.216 1    18.602 ? 1297 GLU A H      1 ? 
ATOM   4743 H HA     . GLU A 1 289 ? 17.192  -13.763 -17.283 1    20.977 ? 1297 GLU A HA     1 c 
ATOM   4744 H HB2    . GLU A 1 289 ? 17.017  -12.96  -14.353 1    23.243 ? 1297 GLU A HB2    1 c 
ATOM   4745 H HB3    . GLU A 1 289 ? 17.902  -14.327 -15.028 1    23.268 ? 1297 GLU A HB3    1 c 
ATOM   4746 H HG2    . GLU A 1 289 ? 19.414  -12.744 -16.226 1    25.619 ? 1297 GLU A HG2    1 c 
ATOM   4747 H HG3    . GLU A 1 289 ? 18.536  -11.38  -15.495 1    25.619 ? 1297 GLU A HG3    1 c 
ATOM   4748 N N      . SER A 1 290 ? 15.584  -15.415 -16.158 1    18.277 ? 1298 SER A N      1 ? 
ATOM   4749 C CA     . SER A 1 290 ? 14.554  -16.354 -15.737 1    20.179 ? 1298 SER A CA     1 ? 
ATOM   4750 C C      . SER A 1 290 ? 14.787  -16.738 -14.282 1    18.908 ? 1298 SER A C      1 ? 
ATOM   4751 O O      . SER A 1 290 ? 15.818  -17.34  -13.964 1    17.824 ? 1298 SER A O      1 ? 
ATOM   4752 C CB     . SER A 1 290 ? 14.566  -17.611 -16.596 1    22.012 ? 1298 SER A CB     1 ? 
ATOM   4753 O OG     . SER A 1 290 ? 13.908  -18.681 -15.936 1    22.075 ? 1298 SER A OG     1 ? 
ATOM   4754 H H      . SER A 1 290 ? 16.491  -15.766 -16.508 1    18.409 ? 1298 SER A H      1 ? 
ATOM   4755 H HA     . SER A 1 290 ? 13.578  -15.872 -15.824 1    19.887 ? 1298 SER A HA     1 c 
ATOM   4756 H HB2    . SER A 1 290 ? 14.065  -17.405 -17.544 1    21.621 ? 1298 SER A HB2    1 c 
ATOM   4757 H HB3    . SER A 1 290 ? 15.599  -17.894 -16.808 1    21.621 ? 1298 SER A HB3    1 c 
ATOM   4758 H HG     . SER A 1 290 ? 12.987  -18.373 -15.885 1    21.977 ? 1298 SER A HG     1 ? 
ATOM   4759 N N      . TRP A 1 291 ? 13.835  -16.411 -13.403 1    19.638 ? 1299 TRP A N      1 ? 
ATOM   4760 C CA     . TRP A 1 291 ? 13.987  -16.799 -12.007 1    20.597 ? 1299 TRP A CA     1 ? 
ATOM   4761 C C      . TRP A 1 291 ? 13.98   -18.318 -11.846 1    18.983 ? 1299 TRP A C      1 ? 
ATOM   4762 O O      . TRP A 1 291 ? 14.721  -18.86  -11.024 1    19.649 ? 1299 TRP A O      1 ? 
ATOM   4763 C CB     . TRP A 1 291 ? 12.942  -16.129 -11.107 1    21.749 ? 1299 TRP A CB     1 ? 
ATOM   4764 C CG     . TRP A 1 291 ? 13.05   -16.611 -9.69   1    21.666 ? 1299 TRP A CG     1 ? 
ATOM   4765 C CD1    . TRP A 1 291 ? 12.125  -17.328 -8.994  1    21.468 ? 1299 TRP A CD1    1 ? 
ATOM   4766 C CD2    . TRP A 1 291 ? 14.185  -16.46  -8.822  1    21.268 ? 1299 TRP A CD2    1 ? 
ATOM   4767 N NE1    . TRP A 1 291 ? 12.6    -17.618 -7.736  1    22.887 ? 1299 TRP A NE1    1 ? 
ATOM   4768 C CE2    . TRP A 1 291 ? 13.86   -17.102 -7.606  1    20.926 ? 1299 TRP A CE2    1 ? 
ATOM   4769 C CE3    . TRP A 1 291 ? 15.43   -15.839 -8.948  1    21.995 ? 1299 TRP A CE3    1 ? 
ATOM   4770 C CZ2    . TRP A 1 291 ? 14.74   -17.14  -6.528  1    18.763 ? 1299 TRP A CZ2    1 ? 
ATOM   4771 C CZ3    . TRP A 1 291 ? 16.301  -15.877 -7.881  1    21.065 ? 1299 TRP A CZ3    1 ? 
ATOM   4772 C CH2    . TRP A 1 291 ? 15.96   -16.524 -6.684  1    20.052 ? 1299 TRP A CH2    1 ? 
ATOM   4773 H H      . TRP A 1 291 ? 12.967  -15.934 -13.696 1    20.698 ? 1299 TRP A H      1 ? 
ATOM   4774 H HA     . TRP A 1 291 ? 14.967  -16.443 -11.68  1    20.298 ? 1299 TRP A HA     1 c 
ATOM   4775 H HB2    . TRP A 1 291 ? 13.1    -15.049 -11.131 1    21.516 ? 1299 TRP A HB2    1 c 
ATOM   4776 H HB3    . TRP A 1 291 ? 11.946  -16.358 -11.491 1    21.484 ? 1299 TRP A HB3    1 c 
ATOM   4777 H HD1    . TRP A 1 291 ? 11.146  -17.617 -9.362  1    21.804 ? 1299 TRP A HD1    1 c 
ATOM   4778 H HE1    . TRP A 1 291 ? 12.075  -18.107 -7.039  1    23.464 ? 1299 TRP A HE1    1 ? 
ATOM   4779 H HE3    . TRP A 1 291 ? 15.704  -15.337 -9.87   1    21.604 ? 1299 TRP A HE3    1 c 
ATOM   4780 H HZ2    . TRP A 1 291 ? 14.474  -17.64  -5.604  1    19.534 ? 1299 TRP A HZ2    1 c 
ATOM   4781 H HZ3    . TRP A 1 291 ? 17.272  -15.402 -7.968  1    21.08  ? 1299 TRP A HZ3    1 c 
ATOM   4782 H HH2    . TRP A 1 291 ? 16.67   -16.537 -5.863  1    20.003 ? 1299 TRP A HH2    1 c 
ATOM   4783 N N      . ASP A 1 292 ? 13.165  -19.025 -12.632 1    21.136 ? 1300 ASP A N      1 ? 
ATOM   4784 C CA     . ASP A 1 292 ? 13.154  -20.484 -12.561 1    22.558 ? 1300 ASP A CA     1 ? 
ATOM   4785 C C      . ASP A 1 292 ? 14.556  -21.039 -12.802 1    20.562 ? 1300 ASP A C      1 ? 
ATOM   4786 O O      . ASP A 1 292 ? 15.048  -21.88  -12.043 1    21.094 ? 1300 ASP A O      1 ? 
ATOM   4787 C CB     . ASP A 1 292 ? 12.179  -21.077 -13.574 1    22.638 ? 1300 ASP A CB     1 ? 
ATOM   4788 C CG     . ASP A 1 292 ? 10.727  -20.815 -13.22  1    24.691 ? 1300 ASP A CG     1 ? 
ATOM   4789 O OD1    . ASP A 1 292 ? 10.41   -20.684 -12.019 1    27.378 ? 1300 ASP A OD1    1 ? 
ATOM   4790 O OD2    . ASP A 1 292 ? 9.894   -20.724 -14.154 1    29.174 ? 1300 ASP A OD2    1 ? 
ATOM   4791 H H      . ASP A 1 292 ? 12.574  -18.541 -13.318 1    18.412 ? 1300 ASP A H      1 ? 
ATOM   4792 H HA     . ASP A 1 292 ? 12.833  -20.777 -11.559 1    21.964 ? 1300 ASP A HA     1 c 
ATOM   4793 H HB2    . ASP A 1 292 ? 12.379  -20.65  -14.559 1    23.057 ? 1300 ASP A HB2    1 c 
ATOM   4794 H HB3    . ASP A 1 292 ? 12.333  -22.157 -13.631 1    23.057 ? 1300 ASP A HB3    1 c 
ATOM   4795 N N      . GLN A 1 293 ? 15.219  -20.572 -13.855 1    21.054 ? 1301 GLN A N      1 ? 
ATOM   4796 C CA     . GLN A 1 293 ? 16.556  -21.066 -14.143 1    24.236 ? 1301 GLN A CA     1 ? 
ATOM   4797 C C      . GLN A 1 293 ? 17.547  -20.661 -13.055 1    21.802 ? 1301 GLN A C      1 ? 
ATOM   4798 O O      . GLN A 1 293 ? 18.434  -21.445 -12.694 1    19.984 ? 1301 GLN A O      1 ? 
ATOM   4799 C CB     . GLN A 1 293 ? 17.016  -20.6   -15.523 1    29.788 ? 1301 GLN A CB     1 ? 
ATOM   4800 C CG     . GLN A 1 293 ? 16.563  -21.549 -16.639 1    38.959 ? 1301 GLN A CG     1 ? 
ATOM   4801 C CD     . GLN A 1 293 ? 16.639  -20.957 -18.039 1    51.493 ? 1301 GLN A CD     1 ? 
ATOM   4802 O OE1    . GLN A 1 293 ? 17.694  -20.491 -18.493 1    50.066 ? 1301 GLN A OE1    1 ? 
ATOM   4803 N NE2    . GLN A 1 293 ? 15.51   -20.975 -18.744 1    56.456 ? 1301 GLN A NE2    1 ? 
ATOM   4804 H H      . GLN A 1 293 ? 14.799  -19.827 -14.435 1    21.811 ? 1301 GLN A H      1 ? 
ATOM   4805 H HA     . GLN A 1 293 ? 16.508  -22.157 -14.164 1    24.014 ? 1301 GLN A HA     1 c 
ATOM   4806 H HB2    . GLN A 1 293 ? 16.614  -19.603 -15.715 1    30.187 ? 1301 GLN A HB2    1 c 
ATOM   4807 H HB3    . GLN A 1 293 ? 18.106  -20.531 -15.531 1    30.187 ? 1301 GLN A HB3    1 c 
ATOM   4808 H HG2    . GLN A 1 293 ? 17.179  -22.45  -16.611 1    39.101 ? 1301 GLN A HG2    1 c 
ATOM   4809 H HG3    . GLN A 1 293 ? 15.533  -21.851 -16.448 1    39.172 ? 1301 GLN A HG3    1 c 
ATOM   4810 H HE21   . GLN A 1 293 ? 14.673  -21.404 -18.355 1    51.607 ? 1301 GLN A HE21   1 ? 
ATOM   4811 H HE22   . GLN A 1 293 ? 15.485  -20.571 -19.676 1    54.327 ? 1301 GLN A HE22   1 ? 
ATOM   4812 N N      . LYS A 1 294 ? 17.421  -19.434 -12.54  1    20.755 ? 1302 LYS A N      1 ? 
ATOM   4813 C CA     . LYS A 1 294 ? 18.319  -18.987 -11.485 1    20.432 ? 1302 LYS A CA     1 ? 
ATOM   4814 C C      . LYS A 1 294 ? 18.141  -19.828 -10.221 1    15.269 ? 1302 LYS A C      1 ? 
ATOM   4815 O O      . LYS A 1 294 ? 19.125  -20.257 -9.609  1    16.763 ? 1302 LYS A O      1 ? 
ATOM   4816 C CB     . LYS A 1 294 ? 18.062  -17.522 -11.17  1    22.748 ? 1302 LYS A CB     1 ? 
ATOM   4817 C CG     . LYS A 1 294 ? 19.164  -16.905 -10.342 0.69 24.967 ? 1302 LYS A CG     1 ? 
ATOM   4818 C CD     . LYS A 1 294 ? 19.081  -15.391 -10.35  0.91 26.85  ? 1302 LYS A CD     1 ? 
ATOM   4819 C CE     . LYS A 1 294 ? 20.466  -14.76  -10.339 0.78 26.099 ? 1302 LYS A CE     1 ? 
ATOM   4820 N NZ     . LYS A 1 294 ? 21.217  -14.905 -11.607 1    25.78  ? 1302 LYS A NZ     1 ? 
ATOM   4821 H H      . LYS A 1 294 ? 16.696  -18.771 -12.875 1    20.842 ? 1302 LYS A H      1 ? 
ATOM   4822 H HA     . LYS A 1 294 ? 19.346  -19.099 -11.839 1    19.828 ? 1302 LYS A HA     1 c 
ATOM   4823 H HB2    . LYS A 1 294 ? 17.97   -16.964 -12.105 0.96 22.71  ? 1302 LYS A HB2    1 c 
ATOM   4824 H HB3    . LYS A 1 294 ? 17.12   -17.43  -10.627 0.6  22.688 ? 1302 LYS A HB3    1 c 
ATOM   4825 H HG2    . LYS A 1 294 ? 19.09   -17.271 -9.316  1    24.893 ? 1302 LYS A HG2    1 c 
ATOM   4826 H HG3    . LYS A 1 294 ? 20.125  -17.211 -10.753 0.26 25.061 ? 1302 LYS A HG3    1 c 
ATOM   4827 H HD2    . LYS A 1 294 ? 18.545  -15.063 -11.243 0.71 26.222 ? 1302 LYS A HD2    1 c 
ATOM   4828 H HD3    . LYS A 1 294 ? 18.527  -15.053 -9.474  0.59 26.203 ? 1302 LYS A HD3    1 c 
ATOM   4829 H HE2    . LYS A 1 294 ? 20.372  -13.697 -10.112 1    26.118 ? 1302 LYS A HE2    1 c 
ATOM   4830 H HE3    . LYS A 1 294 ? 21.051  -15.216 -9.537  0.41 26.174 ? 1302 LYS A HE3    1 c 
ATOM   4831 H HZ1    . LYS A 1 294 ? 21.209  -15.857 -11.953 1    22.842 ? 1302 LYS A HZ1    1 ? 
ATOM   4832 H HZ2    . LYS A 1 294 ? 20.843  -14.295 -12.342 1    25.033 ? 1302 LYS A HZ2    1 ? 
ATOM   4833 H HZ3    . LYS A 1 294 ? 22.187  -14.632 -11.41  1    25.344 ? 1302 LYS A HZ3    1 ? 
ATOM   4834 N N      . LEU A 1 295 ? 16.892  -20.05  -9.811  1    15.223 ? 1303 LEU A N      1 ? 
ATOM   4835 C CA     . LEU A 1 295 ? 16.642  -20.845 -8.615  1    15.341 ? 1303 LEU A CA     1 ? 
ATOM   4836 C C      . LEU A 1 295 ? 17.133  -22.28  -8.788  1    15.928 ? 1303 LEU A C      1 ? 
ATOM   4837 O O      . LEU A 1 295 ? 17.728  -22.854 -7.87   1    18.798 ? 1303 LEU A O      1 ? 
ATOM   4838 C CB     . LEU A 1 295 ? 15.157  -20.798 -8.255  1    15.106 ? 1303 LEU A CB     1 ? 
ATOM   4839 C CG     . LEU A 1 295 ? 14.77   -21.595 -7.005  1    15.853 ? 1303 LEU A CG     1 ? 
ATOM   4840 C CD1    . LEU A 1 295 ? 15.577  -21.176 -5.789  1    15.932 ? 1303 LEU A CD1    1 ? 
ATOM   4841 C CD2    . LEU A 1 295 ? 13.277  -21.433 -6.733  1    18.34  ? 1303 LEU A CD2    1 ? 
ATOM   4842 H H      . LEU A 1 295 ? 16.095  -19.574 -10.269 1    14.591 ? 1303 LEU A H      1 ? 
ATOM   4843 H HA     . LEU A 1 295 ? 17.212  -20.396 -7.799  1    15.386 ? 1303 LEU A HA     1 c 
ATOM   4844 H HB2    . LEU A 1 295 ? 14.875  -19.754 -8.103  1    15.317 ? 1303 LEU A HB2    1 c 
ATOM   4845 H HB3    . LEU A 1 295 ? 14.587  -21.184 -9.103  1    15.317 ? 1303 LEU A HB3    1 c 
ATOM   4846 H HG     . LEU A 1 295 ? 14.967  -22.651 -7.197  1    16.149 ? 1303 LEU A HG     1 c 
ATOM   4847 H HD11   . LEU A 1 295 ? 15.428  -20.111 -5.601  1    15.905 ? 1303 LEU A HD11   1 c 
ATOM   4848 H HD12   . LEU A 1 295 ? 15.247  -21.748 -4.919  1    15.91  ? 1303 LEU A HD12   1 c 
ATOM   4849 H HD13   . LEU A 1 295 ? 16.636  -21.369 -5.968  1    15.882 ? 1303 LEU A HD13   1 c 
ATOM   4850 H HD21   . LEU A 1 295 ? 13.004  -22.002 -5.841  1    17.594 ? 1303 LEU A HD21   1 c 
ATOM   4851 H HD22   . LEU A 1 295 ? 13.047  -20.377 -6.574  1    17.594 ? 1303 LEU A HD22   1 c 
ATOM   4852 H HD23   . LEU A 1 295 ? 12.708  -21.803 -7.588  1    17.537 ? 1303 LEU A HD23   1 c 
ATOM   4853 N N      . ALA A 1 296 ? 16.923  -22.867 -9.969  1    16.754 ? 1304 ALA A N      1 ? 
ATOM   4854 C CA     . ALA A 1 296 ? 17.448  -24.206 -10.219 1    16.841 ? 1304 ALA A CA     1 ? 
ATOM   4855 C C      . ALA A 1 296 ? 18.965  -24.236 -10.044 1    16.83  ? 1304 ALA A C      1 ? 
ATOM   4856 O O      . ALA A 1 296 ? 19.511  -25.181 -9.45   1    16.642 ? 1304 ALA A O      1 ? 
ATOM   4857 C CB     . ALA A 1 296 ? 17.049  -24.69  -11.612 1    17.092 ? 1304 ALA A CB     1 ? 
ATOM   4858 H H      . ALA A 1 296 ? 16.398  -22.365 -10.708 1    16.373 ? 1304 ALA A H      1 ? 
ATOM   4859 H HA     . ALA A 1 296 ? 17.013  -24.879 -9.477  1    16.866 ? 1304 ALA A HA     1 c 
ATOM   4860 H HB1    . ALA A 1 296 ? 17.45   -25.691 -11.782 1    17.02  ? 1304 ALA A HB1    1 c 
ATOM   4861 H HB2    . ALA A 1 296 ? 15.961  -24.718 -11.693 1    17.02  ? 1304 ALA A HB2    1 c 
ATOM   4862 H HB3    . ALA A 1 296 ? 17.449  -24.009 -12.366 1    17.014 ? 1304 ALA A HB3    1 c 
ATOM   4863 N N      . GLN A 1 297 ? 19.661  -23.2   -10.536 1    16.413 ? 1305 GLN A N      1 ? 
ATOM   4864 C CA     . GLN A 1 297 ? 21.109  -23.131 -10.415 1    17.894 ? 1305 GLN A CA     1 ? 
ATOM   4865 C C      . GLN A 1 297 ? 21.507  -22.96  -8.945  1    16.049 ? 1305 GLN A C      1 ? 
ATOM   4866 O O      . GLN A 1 297 ? 22.418  -23.64  -8.475  1    17.421 ? 1305 GLN A O      1 ? 
ATOM   4867 C CB     . GLN A 1 297 ? 21.685  -22.044 -11.328 1    22.558 ? 1305 GLN A CB     1 ? 
ATOM   4868 C CG     . GLN A 1 297 ? 23.191  -22.15  -11.544 1    29.868 ? 1305 GLN A CG     1 ? 
ATOM   4869 C CD     . GLN A 1 297 ? 23.65   -23.543 -11.972 1    36.806 ? 1305 GLN A CD     1 ? 
ATOM   4870 O OE1    . GLN A 1 297 ? 23.142  -24.142 -12.93  1    32.271 ? 1305 GLN A OE1    1 ? 
ATOM   4871 N NE2    . GLN A 1 297 ? 24.633  -24.09  -11.262 1    36.149 ? 1305 GLN A NE2    1 ? 
ATOM   4872 H H      . GLN A 1 297 ? 19.17   -22.412 -10.993 1    17.064 ? 1305 GLN A H      1 ? 
ATOM   4873 H HA     . GLN A 1 297 ? 21.508  -24.088 -10.754 1    18.076 ? 1305 GLN A HA     1 c 
ATOM   4874 H HB2    . GLN A 1 297 ? 21.184  -22.097 -12.296 1    22.847 ? 1305 GLN A HB2    1 c 
ATOM   4875 H HB3    . GLN A 1 297 ? 21.459  -21.075 -10.892 1    23.017 ? 1305 GLN A HB3    1 c 
ATOM   4876 H HG2    . GLN A 1 297 ? 23.495  -21.433 -12.309 1    29.409 ? 1305 GLN A HG2    1 c 
ATOM   4877 H HG3    . GLN A 1 297 ? 23.706  -21.883 -10.618 1    29.445 ? 1305 GLN A HG3    1 c 
ATOM   4878 H HE21   . GLN A 1 297 ? 24.971  -23.638 -10.433 1    35.41  ? 1305 GLN A HE21   1 ? 
ATOM   4879 H HE22   . GLN A 1 297 ? 25.026  -24.96  -11.565 1    33.316 ? 1305 GLN A HE22   1 ? 
ATOM   4880 N N      . LEU A 1 298 ? 20.813  -22.092 -8.205  1    16.523 ? 1306 LEU A N      1 ? 
ATOM   4881 C CA     . LEU A 1 298 ? 21.134  -21.879 -6.796  1    16.933 ? 1306 LEU A CA     1 ? 
ATOM   4882 C C      . LEU A 1 298 ? 20.969  -23.173 -6      1    19.034 ? 1306 LEU A C      1 ? 
ATOM   4883 O O      . LEU A 1 298 ? 21.778  -23.481 -5.114  1    17.512 ? 1306 LEU A O      1 ? 
ATOM   4884 C CB     . LEU A 1 298 ? 20.272  -20.766 -6.218  1    17.68  ? 1306 LEU A CB     1 ? 
ATOM   4885 C CG     . LEU A 1 298 ? 20.546  -19.36  -6.766  1    18.487 ? 1306 LEU A CG     1 ? 
ATOM   4886 C CD1    . LEU A 1 298 ? 19.45   -18.382 -6.329  1    18.81  ? 1306 LEU A CD1    1 ? 
ATOM   4887 C CD2    . LEU A 1 298 ? 21.906  -18.865 -6.316  1    19.865 ? 1306 LEU A CD2    1 ? 
ATOM   4888 H H      . LEU A 1 298 ? 19.992  -21.607 -8.608  1    16.345 ? 1306 LEU A H      1 ? 
ATOM   4889 H HA     . LEU A 1 298 ? 22.182  -21.58  -6.735  1    17.369 ? 1306 LEU A HA     1 c 
ATOM   4890 H HB2    . LEU A 1 298 ? 19.225  -21.012 -6.408  1    17.683 ? 1306 LEU A HB2    1 c 
ATOM   4891 H HB3    . LEU A 1 298 ? 20.418  -20.749 -5.136  1    17.683 ? 1306 LEU A HB3    1 c 
ATOM   4892 H HG     . LEU A 1 298 ? 20.545  -19.411 -7.854  1    18.735 ? 1306 LEU A HG     1 c 
ATOM   4893 H HD11   . LEU A 1 298 ? 19.665  -17.389 -6.73   1    18.713 ? 1306 LEU A HD11   1 c 
ATOM   4894 H HD12   . LEU A 1 298 ? 18.484  -18.724 -6.707  1    18.713 ? 1306 LEU A HD12   1 c 
ATOM   4895 H HD13   . LEU A 1 298 ? 19.417  -18.334 -5.239  1    18.69  ? 1306 LEU A HD13   1 c 
ATOM   4896 H HD21   . LEU A 1 298 ? 21.95   -18.86  -5.225  1    19.455 ? 1306 LEU A HD21   1 c 
ATOM   4897 H HD22   . LEU A 1 298 ? 22.683  -19.524 -6.708  1    19.431 ? 1306 LEU A HD22   1 c 
ATOM   4898 H HD23   . LEU A 1 298 ? 22.067  -17.852 -6.69   1    19.429 ? 1306 LEU A HD23   1 c 
ATOM   4899 N N      . LYS A 1 299 ? 19.906  -23.929 -6.278  1    16.455 ? 1307 LYS A N      1 ? 
ATOM   4900 C CA     . LYS A 1 299 ? 19.685  -25.212 -5.626  1    17.738 ? 1307 LYS A CA     1 ? 
ATOM   4901 C C      . LYS A 1 299 ? 20.777  -26.212 -5.978  1    18.834 ? 1307 LYS A C      1 ? 
ATOM   4902 O O      . LYS A 1 299 ? 21.326  -26.906 -5.113  1    17.629 ? 1307 LYS A O      1 ? 
ATOM   4903 C CB     . LYS A 1 299 ? 18.33   -25.841 -5.94   1    17.077 ? 1307 LYS A CB     1 ? 
ATOM   4904 C CG     . LYS A 1 299 ? 17.18   -25.008 -5.466  1    18.894 ? 1307 LYS A CG     1 ? 
ATOM   4905 C CD     . LYS A 1 299 ? 15.882  -25.784 -5.243  1    21.487 ? 1307 LYS A CD     1 ? 
ATOM   4906 C CE     . LYS A 1 299 ? 14.814  -24.927 -4.637  1    25.536 ? 1307 LYS A CE     1 ? 
ATOM   4907 N NZ     . LYS A 1 299 ? 13.622  -25.774 -4.439  1    28.217 ? 1307 LYS A NZ     1 ? 
ATOM   4908 H H      . LYS A 1 299 ? 19.183  -23.551 -6.925  1    15.513 ? 1307 LYS A H      1 ? 
ATOM   4909 H HA     . LYS A 1 299 ? 19.723  -25.044 -4.548  1    17.557 ? 1307 LYS A HA     1 c 
ATOM   4910 H HB2    . LYS A 1 299 ? 18.241  -25.982 -7.019  1    17.609 ? 1307 LYS A HB2    1 c 
ATOM   4911 H HB3    . LYS A 1 299 ? 18.272  -26.823 -5.465  1    17.609 ? 1307 LYS A HB3    1 c 
ATOM   4912 H HG2    . LYS A 1 299 ? 17.466  -24.525 -4.53   1    18.993 ? 1307 LYS A HG2    1 c 
ATOM   4913 H HG3    . LYS A 1 299 ? 16.996  -24.223 -6.2    1    18.993 ? 1307 LYS A HG3    1 c 
ATOM   4914 H HD2    . LYS A 1 299 ? 15.528  -26.174 -6.2    1    21.714 ? 1307 LYS A HD2    1 c 
ATOM   4915 H HD3    . LYS A 1 299 ? 16.08   -26.631 -4.582  1    21.714 ? 1307 LYS A HD3    1 c 
ATOM   4916 H HE2    . LYS A 1 299 ? 15.145  -24.529 -3.675  1    25.1   ? 1307 LYS A HE2    1 c 
ATOM   4917 H HE3    . LYS A 1 299 ? 14.569  -24.096 -5.302  1    25.138 ? 1307 LYS A HE3    1 c 
ATOM   4918 H HZ1    . LYS A 1 299 ? 12.988  -25.295 -3.792  1    26.278 ? 1307 LYS A HZ1    1 ? 
ATOM   4919 H HZ2    . LYS A 1 299 ? 13.126  -25.936 -5.313  1    26.402 ? 1307 LYS A HZ2    1 ? 
ATOM   4920 H HZ3    . LYS A 1 299 ? 13.918  -26.706 -4.085  1    28.656 ? 1307 LYS A HZ3    1 ? 
ATOM   4921 N N      . LYS A 1 300 ? 21.099  -26.297 -7.268  1    19.002 ? 1308 LYS A N      1 ? 
ATOM   4922 C CA     . LYS A 1 300 ? 22.131  -27.232 -7.699  1    22.189 ? 1308 LYS A CA     1 ? 
ATOM   4923 C C      . LYS A 1 300 ? 23.483  -26.912 -7.033  1    21.592 ? 1308 LYS A C      1 ? 
ATOM   4924 O O      . LYS A 1 300 ? 24.226  -27.815 -6.659  1    19.652 ? 1308 LYS A O      1 ? 
ATOM   4925 C CB     . LYS A 1 300 ? 22.252  -27.191 -9.219  1    25.564 ? 1308 LYS A CB     1 ? 
ATOM   4926 C CG     . LYS A 1 300 ? 23.269  -28.155 -9.773  1    29.715 ? 1308 LYS A CG     1 ? 
ATOM   4927 C CD     . LYS A 1 300 ? 23.07   -28.547 -11.213 1    33.213 ? 1308 LYS A CD     1 ? 
ATOM   4928 C CE     . LYS A 1 300 ? 24.397  -29     -11.785 1    38.496 ? 1308 LYS A CE     1 ? 
ATOM   4929 N NZ     . LYS A 1 300 ? 24.274  -29.186 -13.241 1    45.494 ? 1308 LYS A NZ     1 ? 
ATOM   4930 H H      . LYS A 1 300 ? 20.667  -25.649 -7.942  1    18.613 ? 1308 LYS A H      1 ? 
ATOM   4931 H HA     . LYS A 1 300 ? 21.827  -28.237 -7.4    1    22.127 ? 1308 LYS A HA     1 c 
ATOM   4932 H HB2    . LYS A 1 300 ? 21.279  -27.419 -9.659  1    25.63  ? 1308 LYS A HB2    1 c 
ATOM   4933 H HB3    . LYS A 1 300 ? 22.529  -26.18  -9.525  1    25.63  ? 1308 LYS A HB3    1 c 
ATOM   4934 H HG2    . LYS A 1 300 ? 24.259  -27.707 -9.666  1    29.502 ? 1308 LYS A HG2    1 c 
ATOM   4935 H HG3    . LYS A 1 300 ? 23.252  -29.059 -9.159  1    29.463 ? 1308 LYS A HG3    1 c 
ATOM   4936 H HD2    . LYS A 1 300 ? 22.346  -29.361 -11.28  1    33.475 ? 1308 LYS A HD2    1 c 
ATOM   4937 H HD3    . LYS A 1 300 ? 22.7    -27.691 -11.783 1    33.475 ? 1308 LYS A HD3    1 c 
ATOM   4938 H HE2    . LYS A 1 300 ? 25.166  -28.253 -11.58  1    38.718 ? 1308 LYS A HE2    1 c 
ATOM   4939 H HE3    . LYS A 1 300 ? 24.697  -29.944 -11.325 1    38.718 ? 1308 LYS A HE3    1 c 
ATOM   4940 H HZ1    . LYS A 1 300 ? 24.244  -28.279 -13.725 1    41.992 ? 1308 LYS A HZ1    1 ? 
ATOM   4941 H HZ2    . LYS A 1 300 ? 25.064  -29.704 -13.598 1    39.852 ? 1308 LYS A HZ2    1 ? 
ATOM   4942 H HZ3    . LYS A 1 300 ? 23.429  -29.732 -13.437 1    39.922 ? 1308 LYS A HZ3    1 ? 
ATOM   4943 N N      . ASN A 1 301 ? 23.791  -25.615 -6.884  1    20.573 ? 1309 ASN A N      1 ? 
ATOM   4944 C CA     . ASN A 1 301 ? 25.05   -25.172 -6.295  1    20.477 ? 1309 ASN A CA     1 ? 
ATOM   4945 C C      . ASN A 1 301 ? 25.003  -25.151 -4.755  1    19.503 ? 1309 ASN A C      1 ? 
ATOM   4946 O O      . ASN A 1 301 ? 25.999  -24.762 -4.136  1    18.61  ? 1309 ASN A O      1 ? 
ATOM   4947 C CB     . ASN A 1 301 ? 25.419  -23.748 -6.706  1    24.125 ? 1309 ASN A CB     1 ? 
ATOM   4948 C CG     . ASN A 1 301 ? 25.695  -23.562 -8.183  1    29.79  ? 1309 ASN A CG     1 ? 
ATOM   4949 O OD1    . ASN A 1 301 ? 25.941  -24.548 -8.889  1    28.74  ? 1309 ASN A OD1    1 ? 
ATOM   4950 N ND2    . ASN A 1 301 ? 25.644  -22.316 -8.672  1    32.412 ? 1309 ASN A ND2    1 ? 
ATOM   4951 H H      . ASN A 1 301 ? 23.104  -24.884 -7.152  1    19.524 ? 1309 ASN A H      1 ? 
ATOM   4952 H HA     . ASN A 1 301 ? 25.849  -25.838 -6.625  1    20.957 ? 1309 ASN A HA     1 c 
ATOM   4953 H HB2    . ASN A 1 301 ? 24.603  -23.081 -6.419  1    24.355 ? 1309 ASN A HB2    1 c 
ATOM   4954 H HB3    . ASN A 1 301 ? 26.305  -23.443 -6.147  1    24.45  ? 1309 ASN A HB3    1 c 
ATOM   4955 H HD21   . ASN A 1 301 ? 25.859  -22.137 -9.657  1    30.549 ? 1309 ASN A HD21   1 ? 
ATOM   4956 H HD22   . ASN A 1 301 ? 25.365  -21.52  -8.083  1    30.11  ? 1309 ASN A HD22   1 ? 
ATOM   4957 N N      . LYS A 1 302 ? 23.885  -25.555 -4.144  1    19.819 ? 1310 LYS A N      1 ? 
ATOM   4958 C CA     . LYS A 1 302 ? 23.753  -25.633 -2.684  1    21.709 ? 1310 LYS A CA     1 ? 
ATOM   4959 C C      . LYS A 1 302 ? 23.883  -24.258 -2.02   1    17.685 ? 1310 LYS A C      1 ? 
ATOM   4960 O O      . LYS A 1 302 ? 24.417  -24.129 -0.913  1    15.38  ? 1310 LYS A O      1 ? 
ATOM   4961 C CB     . LYS A 1 302 ? 24.694  -26.669 -2.073  1    25.54  ? 1310 LYS A CB     1 ? 
ATOM   4962 C CG     . LYS A 1 302 ? 24.637  -28.04  -2.731  1    36.74  ? 1310 LYS A CG     1 ? 
ATOM   4963 C CD     . LYS A 1 302 ? 25.761  -28.984 -2.283  1    46.701 ? 1310 LYS A CD     1 ? 
ATOM   4964 C CE     . LYS A 1 302 ? 27.149  -28.335 -2.195  1    59.132 ? 1310 LYS A CE     1 ? 
ATOM   4965 N NZ     . LYS A 1 302 ? 28.216  -29.216 -1.68   1    69.006 ? 1310 LYS A NZ     1 ? 
ATOM   4966 H H      . LYS A 1 302 ? 23.059  -25.748 -4.731  1    18.806 ? 1310 LYS A H      1 ? 
ATOM   4967 H HA     . LYS A 1 302 ? 22.745  -25.991 -2.479  1    21.237 ? 1310 LYS A HA     1 c 
ATOM   4968 H HB2    . LYS A 1 302 ? 25.715  -26.289 -2.143  1    27     ? 1310 LYS A HB2    1 c 
ATOM   4969 H HB3    . LYS A 1 302 ? 24.454  -26.782 -1.014  1    26.774 ? 1310 LYS A HB3    1 c 
ATOM   4970 H HG2    . LYS A 1 302 ? 23.674  -28.498 -2.497  1    35.672 ? 1310 LYS A HG2    1 c 
ATOM   4971 H HG3    . LYS A 1 302 ? 24.692  -27.911 -3.814  1    35.569 ? 1310 LYS A HG3    1 c 
ATOM   4972 H HD2    . LYS A 1 302 ? 25.502  -29.393 -1.305  1    46.692 ? 1310 LYS A HD2    1 c 
ATOM   4973 H HD3    . LYS A 1 302 ? 25.81   -29.821 -2.983  1    46.659 ? 1310 LYS A HD3    1 c 
ATOM   4974 H HE2    . LYS A 1 302 ? 27.438  -27.984 -3.188  1    58.052 ? 1310 LYS A HE2    1 c 
ATOM   4975 H HE3    . LYS A 1 302 ? 27.096  -27.464 -1.54   1    57.476 ? 1310 LYS A HE3    1 c 
ATOM   4976 H HZ1    . LYS A 1 302 ? 27.977  -29.587 -0.748  1    65.681 ? 1310 LYS A HZ1    1 ? 
ATOM   4977 H HZ2    . LYS A 1 302 ? 28.377  -29.996 -2.323  1    65.469 ? 1310 LYS A HZ2    1 ? 
ATOM   4978 H HZ3    . LYS A 1 302 ? 29.079  -28.686 -1.603  1    64.931 ? 1310 LYS A HZ3    1 ? 
ATOM   4979 N N      . GLN A 1 303 ? 23.341  -23.237 -2.689  1    16.068 ? 1311 GLN A N      1 ? 
ATOM   4980 C CA     . GLN A 1 303 ? 23.328  -21.878 -2.175  1    15.894 ? 1311 GLN A CA     1 ? 
ATOM   4981 C C      . GLN A 1 303 ? 22.006  -21.49  -1.517  1    15.623 ? 1311 GLN A C      1 ? 
ATOM   4982 O O      . GLN A 1 303 ? 21.917  -20.399 -0.949  1    14.146 ? 1311 GLN A O      1 ? 
ATOM   4983 C CB     . GLN A 1 303 ? 23.583  -20.884 -3.308  1    17.203 ? 1311 GLN A CB     1 ? 
ATOM   4984 C CG     . GLN A 1 303 ? 25.002  -20.859 -3.85   1    16.754 ? 1311 GLN A CG     1 ? 
ATOM   4985 C CD     . GLN A 1 303 ? 25.075  -20.034 -5.121  1    17.225 ? 1311 GLN A CD     1 ? 
ATOM   4986 O OE1    . GLN A 1 303 ? 25.027  -20.547 -6.236  1    17.619 ? 1311 GLN A OE1    1 ? 
ATOM   4987 N NE2    . GLN A 1 303 ? 25.141  -18.72  -4.96   1    16.773 ? 1311 GLN A NE2    1 ? 
ATOM   4988 H H      . GLN A 1 303 ? 22.942  -23.396 -3.634  1    17.128 ? 1311 GLN A H      1 ? 
ATOM   4989 H HA     . GLN A 1 303 ? 24.127  -21.78  -1.438  1    16.097 ? 1311 GLN A HA     1 c 
ATOM   4990 H HB2    . GLN A 1 303 ? 22.901  -21.119 -4.128  1    16.805 ? 1311 GLN A HB2    1 c 
ATOM   4991 H HB3    . GLN A 1 303 ? 23.33   -19.884 -2.95   1    16.785 ? 1311 GLN A HB3    1 c 
ATOM   4992 H HG2    . GLN A 1 303 ? 25.673  -20.431 -3.102  1    16.953 ? 1311 GLN A HG2    1 c 
ATOM   4993 H HG3    . GLN A 1 303 ? 25.333  -21.878 -4.06   1    16.953 ? 1311 GLN A HG3    1 c 
ATOM   4994 H HE21   . GLN A 1 303 ? 25.034  -18.304 -4.038  1    15.589 ? 1311 GLN A HE21   1 ? 
ATOM   4995 H HE22   . GLN A 1 303 ? 25.167  -18.149 -5.78   1    15.436 ? 1311 GLN A HE22   1 ? 
ATOM   4996 N N      . TRP A 1 304 ? 20.979  -22.342 -1.594  1    15.121 ? 1312 TRP A N      1 ? 
ATOM   4997 C CA     . TRP A 1 304 ? 19.608  -21.964 -1.272  1    16.639 ? 1312 TRP A CA     1 ? 
ATOM   4998 C C      . TRP A 1 304 ? 19.15   -22.773 -0.061  1    17.161 ? 1312 TRP A C      1 ? 
ATOM   4999 O O      . TRP A 1 304 ? 19.058  -23.999 -0.142  1    21.247 ? 1312 TRP A O      1 ? 
ATOM   5000 C CB     . TRP A 1 304 ? 18.72   -22.249 -2.485  1    16.133 ? 1312 TRP A CB     1 ? 
ATOM   5001 C CG     . TRP A 1 304 ? 17.281  -21.872 -2.338  1    17.28  ? 1312 TRP A CG     1 ? 
ATOM   5002 C CD1    . TRP A 1 304 ? 16.257  -22.678 -1.95   1    17.367 ? 1312 TRP A CD1    1 ? 
ATOM   5003 C CD2    . TRP A 1 304 ? 16.701  -20.589 -2.632  1    16.296 ? 1312 TRP A CD2    1 ? 
ATOM   5004 N NE1    . TRP A 1 304 ? 15.078  -21.978 -1.965  1    18.7   ? 1312 TRP A NE1    1 ? 
ATOM   5005 C CE2    . TRP A 1 304 ? 15.317  -20.696 -2.38   1    17.327 ? 1312 TRP A CE2    1 ? 
ATOM   5006 C CE3    . TRP A 1 304 ? 17.213  -19.372 -3.087  1    16.847 ? 1312 TRP A CE3    1 ? 
ATOM   5007 C CZ2    . TRP A 1 304 ? 14.439  -19.627 -2.55   1    19.007 ? 1312 TRP A CZ2    1 ? 
ATOM   5008 C CZ3    . TRP A 1 304 ? 16.344  -18.311 -3.263  1    18.109 ? 1312 TRP A CZ3    1 ? 
ATOM   5009 C CH2    . TRP A 1 304 ? 14.971  -18.443 -2.999  1    18.249 ? 1312 TRP A CH2    1 ? 
ATOM   5010 H H      . TRP A 1 304 ? 21.156  -23.271 -1.997  1    15.014 ? 1312 TRP A H      1 ? 
ATOM   5011 H HA     . TRP A 1 304 ? 19.569  -20.898 -1.038  1    16.328 ? 1312 TRP A HA     1 c 
ATOM   5012 H HB2    . TRP A 1 304 ? 19.133  -21.717 -3.345  1    16.492 ? 1312 TRP A HB2    1 c 
ATOM   5013 H HB3    . TRP A 1 304 ? 18.78   -23.316 -2.71   1    16.492 ? 1312 TRP A HB3    1 c 
ATOM   5014 H HD1    . TRP A 1 304 ? 16.349  -23.716 -1.656  1    17.917 ? 1312 TRP A HD1    1 c 
ATOM   5015 H HE1    . TRP A 1 304 ? 14.199  -22.345 -1.71   1    20.421 ? 1312 TRP A HE1    1 ? 
ATOM   5016 H HE3    . TRP A 1 304 ? 18.273  -19.261 -3.288  1    17.02  ? 1312 TRP A HE3    1 c 
ATOM   5017 H HZ2    . TRP A 1 304 ? 13.377  -19.733 -2.354  1    18.446 ? 1312 TRP A HZ2    1 c 
ATOM   5018 H HZ3    . TRP A 1 304 ? 16.73   -17.358 -3.609  1    17.848 ? 1312 TRP A HZ3    1 c 
ATOM   5019 H HH2    . TRP A 1 304 ? 14.316  -17.591 -3.148  1    18.359 ? 1312 TRP A HH2    1 c 
ATOM   5020 N N      . HIS A 1 305 ? 18.861  -22.103 1.054   1    16.185 ? 1313 HIS A N      1 ? 
ATOM   5021 C CA     . HIS A 1 305 ? 18.628  -22.791 2.324   1    15.755 ? 1313 HIS A CA     1 ? 
ATOM   5022 C C      . HIS A 1 305 ? 17.331  -22.292 2.942   1    14.896 ? 1313 HIS A C      1 ? 
ATOM   5023 O O      . HIS A 1 305 ? 17.257  -21.142 3.368   1    14.879 ? 1313 HIS A O      1 ? 
ATOM   5024 C CB     . HIS A 1 305 ? 19.803  -22.547 3.274   1    17.744 ? 1313 HIS A CB     1 ? 
ATOM   5025 C CG     . HIS A 1 305 ? 21.134  -22.718 2.617   1    17.378 ? 1313 HIS A CG     1 ? 
ATOM   5026 N ND1    . HIS A 1 305 ? 21.654  -23.953 2.297   1    19.699 ? 1313 HIS A ND1    1 ? 
ATOM   5027 C CD2    . HIS A 1 305 ? 22.028  -21.81  2.172   1    18.285 ? 1313 HIS A CD2    1 ? 
ATOM   5028 C CE1    . HIS A 1 305 ? 22.831  -23.798 1.71    1    19.153 ? 1313 HIS A CE1    1 ? 
ATOM   5029 N NE2    . HIS A 1 305 ? 23.085  -22.506 1.627   1    17.796 ? 1313 HIS A NE2    1 ? 
ATOM   5030 H H      . HIS A 1 305 ? 18.845  -21.072 1.043   1    15.684 ? 1313 HIS A H      1 ? 
ATOM   5031 H HA     . HIS A 1 305 ? 18.534  -23.861 2.14    1    16.176 ? 1313 HIS A HA     1 c 
ATOM   5032 H HB2    . HIS A 1 305 ? 19.731  -21.532 3.669   1    17.184 ? 1313 HIS A HB2    1 c 
ATOM   5033 H HB3    . HIS A 1 305 ? 19.728  -23.242 4.112   1    17.207 ? 1313 HIS A HB3    1 c 
ATOM   5034 H HD1    . HIS A 1 305 ? 21.2    -24.829 2.495   1    18.729 ? 1313 HIS A HD1    1 ? 
ATOM   5035 H HD2    . HIS A 1 305 ? 21.962  -20.731 2.271   1    18.002 ? 1313 HIS A HD2    1 c 
ATOM   5036 H HE1    . HIS A 1 305 ? 23.478  -24.597 1.372   1    19.111 ? 1313 HIS A HE1    1 c 
ATOM   5037 H HE2    . HIS A 1 305 ? 23.942  -22.118 1.273   1    18.463 ? 1313 HIS A HE2    1 ? 
ATOM   5038 N N      . VAL A 1 306 ? 16.321  -23.158 3.02    1    16.047 ? 1314 VAL A N      1 ? 
ATOM   5039 C CA     . VAL A 1 306 ? 14.997  -22.754 3.482   1    16.864 ? 1314 VAL A CA     1 ? 
ATOM   5040 C C      . VAL A 1 306 ? 14.55   -23.655 4.623   1    17.82  ? 1314 VAL A C      1 ? 
ATOM   5041 O O      . VAL A 1 306 ? 14.498  -24.877 4.47    1    16.932 ? 1314 VAL A O      1 ? 
ATOM   5042 C CB     . VAL A 1 306 ? 13.948  -22.814 2.355   1    18.434 ? 1314 VAL A CB     1 ? 
ATOM   5043 C CG1    . VAL A 1 306 ? 12.586  -22.445 2.9     1    18.508 ? 1314 VAL A CG1    1 ? 
ATOM   5044 C CG2    . VAL A 1 306 ? 14.33   -21.906 1.185   1    19.97  ? 1314 VAL A CG2    1 ? 
ATOM   5045 H H      . VAL A 1 306 ? 16.463  -24.127 2.678   1    15.885 ? 1314 VAL A H      1 ? 
ATOM   5046 H HA     . VAL A 1 306 ? 15.053  -21.729 3.851   1    17.107 ? 1314 VAL A HA     1 c 
ATOM   5047 H HB     . VAL A 1 306 ? 13.91   -23.844 1.996   1    18.417 ? 1314 VAL A HB     1 c 
ATOM   5048 H HG11   . VAL A 1 306 ? 12.239  -23.225 3.581   1    18.492 ? 1314 VAL A HG11   1 c 
ATOM   5049 H HG12   . VAL A 1 306 ? 12.651  -21.496 3.437   1    18.495 ? 1314 VAL A HG12   1 c 
ATOM   5050 H HG13   . VAL A 1 306 ? 11.878  -22.348 2.075   1    18.524 ? 1314 VAL A HG13   1 c 
ATOM   5051 H HG21   . VAL A 1 306 ? 14.358  -20.869 1.524   1    19.412 ? 1314 VAL A HG21   1 c 
ATOM   5052 H HG22   . VAL A 1 306 ? 15.313  -22.192 0.806   1    19.473 ? 1314 VAL A HG22   1 c 
ATOM   5053 H HG23   . VAL A 1 306 ? 13.59   -22.007 0.389   1    19.452 ? 1314 VAL A HG23   1 c 
ATOM   5054 N N      . GLU A 1 307 ? 14.182  -23.052 5.747   1    17.287 ? 1315 GLU A N      1 ? 
ATOM   5055 C CA     . GLU A 1 307 ? 13.512  -23.784 6.818   1    17.969 ? 1315 GLU A CA     1 ? 
ATOM   5056 C C      . GLU A 1 307 ? 12.359  -22.924 7.322   1    17.954 ? 1315 GLU A C      1 ? 
ATOM   5057 O O      . GLU A 1 307 ? 12.543  -22.023 8.146   1    19.023 ? 1315 GLU A O      1 ? 
ATOM   5058 C CB     . GLU A 1 307 ? 14.474  -24.187 7.934   1    19.924 ? 1315 GLU A CB     1 ? 
ATOM   5059 C CG     . GLU A 1 307 ? 13.798  -25.013 9.021   1    20.473 ? 1315 GLU A CG     1 ? 
ATOM   5060 C CD     . GLU A 1 307 ? 14.749  -26.053 9.629   1    22.169 ? 1315 GLU A CD     1 ? 
ATOM   5061 O OE1    . GLU A 1 307 ? 15.648  -25.629 10.368  1    22.445 ? 1315 GLU A OE1    1 ? 
ATOM   5062 O OE2    . GLU A 1 307 ? 14.576  -27.271 9.413   1    20.96  ? 1315 GLU A OE2    1 ? 
ATOM   5063 H H      . GLU A 1 307 ? 14.534  -22.103 5.953   1    16.676 ? 1315 GLU A H      1 ? 
ATOM   5064 H HA     . GLU A 1 307 ? 13.091  -24.697 6.392   1    18.161 ? 1315 GLU A HA     1 c 
ATOM   5065 H HB2    . GLU A 1 307 ? 15.295  -24.763 7.503   1    19.596 ? 1315 GLU A HB2    1 c 
ATOM   5066 H HB3    . GLU A 1 307 ? 14.897  -23.284 8.379   1    19.596 ? 1315 GLU A HB3    1 c 
ATOM   5067 H HG2    . GLU A 1 307 ? 13.447  -24.35  9.815   1    20.707 ? 1315 GLU A HG2    1 c 
ATOM   5068 H HG3    . GLU A 1 307 ? 12.933  -25.529 8.6     1    20.707 ? 1315 GLU A HG3    1 c 
ATOM   5069 N N      . VAL A 1 308 ? 11.165  -23.212 6.815   1    17.259 ? 1316 VAL A N      1 ? 
ATOM   5070 C CA     . VAL A 1 308 ? 9.975   -22.458 7.163   1    17.24  ? 1316 VAL A CA     1 ? 
ATOM   5071 C C      . VAL A 1 308 ? 8.932   -23.437 7.686   1    18.028 ? 1316 VAL A C      1 ? 
ATOM   5072 O O      . VAL A 1 308 ? 8.986   -24.639 7.426   1    18.231 ? 1316 VAL A O      1 ? 
ATOM   5073 C CB     . VAL A 1 308 ? 9.442   -21.611 5.988   1    19.582 ? 1316 VAL A CB     1 ? 
ATOM   5074 C CG1    . VAL A 1 308 ? 10.474  -20.547 5.612   1    18.437 ? 1316 VAL A CG1    1 ? 
ATOM   5075 C CG2    . VAL A 1 308 ? 9.08    -22.481 4.784   1    18.373 ? 1316 VAL A CG2    1 ? 
ATOM   5076 H H      . VAL A 1 308 ? 11.089  -23.979 6.118   1    18.63  ? 1316 VAL A H      1 ? 
ATOM   5077 H HA     . VAL A 1 308 ? 10.236  -21.78  7.974   1    17.772 ? 1316 VAL A HA     1 c 
ATOM   5078 H HB     . VAL A 1 308 ? 8.54    -21.107 6.336   1    18.804 ? 1316 VAL A HB     1 c 
ATOM   5079 H HG11   . VAL A 1 308 ? 11.406  -21.031 5.315   1    18.736 ? 1316 VAL A HG11   1 c 
ATOM   5080 H HG12   . VAL A 1 308 ? 10.095  -19.948 4.781   1    18.736 ? 1316 VAL A HG12   1 c 
ATOM   5081 H HG13   . VAL A 1 308 ? 10.659  -19.898 6.471   1    18.703 ? 1316 VAL A HG13   1 c 
ATOM   5082 H HG21   . VAL A 1 308 ? 8.767   -21.843 3.955   1    18.818 ? 1316 VAL A HG21   1 c 
ATOM   5083 H HG22   . VAL A 1 308 ? 9.95    -23.067 4.482   1    18.712 ? 1316 VAL A HG22   1 c 
ATOM   5084 H HG23   . VAL A 1 308 ? 8.264   -23.156 5.051   1    18.685 ? 1316 VAL A HG23   1 c 
ATOM   5085 N N      . TYR A 1 309 ? 7.968   -22.903 8.431   1    19.246 ? 1317 TYR A N      1 ? 
ATOM   5086 C CA     . TYR A 1 309 ? 7.09    -23.776 9.194   1    20.866 ? 1317 TYR A CA     1 ? 
ATOM   5087 C C      . TYR A 1 309 ? 5.705   -23.172 9.423   1    21.085 ? 1317 TYR A C      1 ? 
ATOM   5088 O O      . TYR A 1 309 ? 5.43    -22.018 9.108   1    20.89  ? 1317 TYR A O      1 ? 
ATOM   5089 C CB     . TYR A 1 309 ? 7.752   -24.134 10.532  1    19.067 ? 1317 TYR A CB     1 ? 
ATOM   5090 C CG     . TYR A 1 309 ? 8.426   -22.965 11.213  1    19.054 ? 1317 TYR A CG     1 ? 
ATOM   5091 C CD1    . TYR A 1 309 ? 7.689   -22.07  11.976  1    17.503 ? 1317 TYR A CD1    1 ? 
ATOM   5092 C CD2    . TYR A 1 309 ? 9.795   -22.749 11.079  1    17.766 ? 1317 TYR A CD2    1 ? 
ATOM   5093 C CE1    . TYR A 1 309 ? 8.295   -20.996 12.61   1    17.174 ? 1317 TYR A CE1    1 ? 
ATOM   5094 C CE2    . TYR A 1 309 ? 10.412  -21.684 11.708  1    17.468 ? 1317 TYR A CE2    1 ? 
ATOM   5095 C CZ     . TYR A 1 309 ? 9.657   -20.806 12.474  1    18.244 ? 1317 TYR A CZ     1 ? 
ATOM   5096 O OH     . TYR A 1 309 ? 10.237  -19.739 13.114  1    16.753 ? 1317 TYR A OH     1 ? 
ATOM   5097 O OXT    . TYR A 1 309 ? 4.846   -23.901 9.958   1    23.416 ? 1317 TYR A OXT    1 ? 
ATOM   5098 H H      . TYR A 1 309 ? 7.854   -21.875 8.487   1    19.527 ? 1317 TYR A H      1 ? 
ATOM   5099 H HA     . TYR A 1 309 ? 6.96    -24.7   8.627   1    20.234 ? 1317 TYR A HA     1 c 
ATOM   5100 H HB2    . TYR A 1 309 ? 6.99    -24.542 11.199  1    19.462 ? 1317 TYR A HB2    1 c 
ATOM   5101 H HB3    . TYR A 1 309 ? 8.495   -24.915 10.354  1    19.445 ? 1317 TYR A HB3    1 c 
ATOM   5102 H HD1    . TYR A 1 309 ? 6.621   -22.22  12.09   1    17.761 ? 1317 TYR A HD1    1 c 
ATOM   5103 H HD2    . TYR A 1 309 ? 10.39   -23.436 10.487  1    17.968 ? 1317 TYR A HD2    1 c 
ATOM   5104 H HE1    . TYR A 1 309 ? 7.706   -20.31  13.211  1    17.482 ? 1317 TYR A HE1    1 c 
ATOM   5105 H HE2    . TYR A 1 309 ? 11.481  -21.532 11.602  1    17.699 ? 1317 TYR A HE2    1 c 
ATOM   5106 H HH     . TYR A 1 309 ? 11.173  -19.783 13.086  1    18.63  ? 1317 TYR A HH     1 ? 
HETATM 5107 P PA     . FAD B 2 .   ? -0.4    -26.408 18.937  1    17.653 ? 1401 FAD A PA     1 ? 
HETATM 5108 O O1A    . FAD B 2 .   ? -0.95   -26.749 20.277  1    18.241 ? 1401 FAD A O1A    1 ? 
HETATM 5109 O O2A    . FAD B 2 .   ? 0.269   -27.472 18.148  1    19.906 ? 1401 FAD A O2A    1 ? 
HETATM 5110 O O5B    . FAD B 2 .   ? -1.513  -25.673 18.075  1    18.619 ? 1401 FAD A O5B    1 ? 
HETATM 5111 C C5B    . FAD B 2 .   ? -1.216  -25.23  16.729  1    21.016 ? 1401 FAD A C5B    1 ? 
HETATM 5112 C C4B    . FAD B 2 .   ? -2.136  -24.078 16.405  1    21.058 ? 1401 FAD A C4B    1 ? 
HETATM 5113 O O4B    . FAD B 2 .   ? -3.501  -24.559 16.429  1    24.154 ? 1401 FAD A O4B    1 ? 
HETATM 5114 C C3B    . FAD B 2 .   ? -2.075  -22.901 17.385  1    22.372 ? 1401 FAD A C3B    1 ? 
HETATM 5115 O O3B    . FAD B 2 .   ? -2.21   -21.633 16.76   1    21.668 ? 1401 FAD A O3B    1 ? 
HETATM 5116 C C2B    . FAD B 2 .   ? -3.354  -23.056 18.214  1    24.041 ? 1401 FAD A C2B    1 ? 
HETATM 5117 O O2B    . FAD B 2 .   ? -3.834  -21.779 18.628  1    25.488 ? 1401 FAD A O2B    1 ? 
HETATM 5118 C C1B    . FAD B 2 .   ? -4.288  -23.64  17.159  1    23.722 ? 1401 FAD A C1B    1 ? 
HETATM 5119 N N9A    . FAD B 2 .   ? -5.462  -24.324 17.671  1    26.617 ? 1401 FAD A N9A    1 ? 
HETATM 5120 C C8A    . FAD B 2 .   ? -5.523  -25.38  18.545  1    27.534 ? 1401 FAD A C8A    1 ? 
HETATM 5121 N N7A    . FAD B 2 .   ? -6.736  -25.838 18.745  1    29.052 ? 1401 FAD A N7A    1 ? 
HETATM 5122 C C5A    . FAD B 2 .   ? -7.53   -25.029 17.942  1    27.131 ? 1401 FAD A C5A    1 ? 
HETATM 5123 C C6A    . FAD B 2 .   ? -8.911  -25.026 17.669  1    30.459 ? 1401 FAD A C6A    1 ? 
HETATM 5124 N N6A    . FAD B 2 .   ? -9.759  -25.866 18.232  1    29.935 ? 1401 FAD A N6A    1 ? 
HETATM 5125 N N1A    . FAD B 2 .   ? -9.387  -24.103 16.798  1    27.018 ? 1401 FAD A N1A    1 ? 
HETATM 5126 C C2A    . FAD B 2 .   ? -8.53   -23.24  16.242  1    28.801 ? 1401 FAD A C2A    1 ? 
HETATM 5127 N N3A    . FAD B 2 .   ? -7.202  -23.148 16.414  1    28.217 ? 1401 FAD A N3A    1 ? 
HETATM 5128 C C4A    . FAD B 2 .   ? -6.761  -24.088 17.28   1    26.284 ? 1401 FAD A C4A    1 ? 
HETATM 5129 N N1     . FAD B 2 .   ? 7.925   -21.615 16.507  1    16.804 ? 1401 FAD A N1     1 ? 
HETATM 5130 C C2     . FAD B 2 .   ? 8.444   -20.563 17.185  1    16.933 ? 1401 FAD A C2     1 ? 
HETATM 5131 O O2     . FAD B 2 .   ? 7.762   -19.824 17.879  1    17.213 ? 1401 FAD A O2     1 ? 
HETATM 5132 N N3     . FAD B 2 .   ? 9.792   -20.305 17.132  1    18.446 ? 1401 FAD A N3     1 ? 
HETATM 5133 C C4     . FAD B 2 .   ? 10.72   -21.013 16.418  1    16.202 ? 1401 FAD A C4     1 ? 
HETATM 5134 O O4     . FAD B 2 .   ? 11.905  -20.692 16.481  1    19.061 ? 1401 FAD A O4     1 ? 
HETATM 5135 C C4X    . FAD B 2 .   ? 10.201  -22.1   15.705  1    16.232 ? 1401 FAD A C4X    1 ? 
HETATM 5136 N N5     . FAD B 2 .   ? 11.02   -22.826 15.02   1    16.161 ? 1401 FAD A N5     1 ? 
HETATM 5137 C C5X    . FAD B 2 .   ? 10.527  -23.921 14.338  1    16.036 ? 1401 FAD A C5X    1 ? 
HETATM 5138 C C6     . FAD B 2 .   ? 11.425  -24.696 13.622  1    16.305 ? 1401 FAD A C6     1 ? 
HETATM 5139 C C7     . FAD B 2 .   ? 10.983  -25.787 12.88   1    17.448 ? 1401 FAD A C7     1 ? 
HETATM 5140 C C7M    . FAD B 2 .   ? 11.974  -26.6   12.1    1    16.804 ? 1401 FAD A C7M    1 ? 
HETATM 5141 C C8     . FAD B 2 .   ? 9.617   -26.12  12.866  1    16.1   ? 1401 FAD A C8     1 ? 
HETATM 5142 C C8M    . FAD B 2 .   ? 9.128   -27.293 12.056  1    17.722 ? 1401 FAD A C8M    1 ? 
HETATM 5143 C C9     . FAD B 2 .   ? 8.711   -25.35  13.583  1    15.284 ? 1401 FAD A C9     1 ? 
HETATM 5144 C C9A    . FAD B 2 .   ? 9.152   -24.253 14.327  1    15.545 ? 1401 FAD A C9A    1 ? 
HETATM 5145 N N10    . FAD B 2 .   ? 8.274   -23.443 15.076  1    15.795 ? 1401 FAD A N10    1 ? 
HETATM 5146 C C10    . FAD B 2 .   ? 8.759   -22.345 15.79   1    16.226 ? 1401 FAD A C10    1 ? 
HETATM 5147 C "C1'"  . FAD B 2 .   ? 6.847   -23.809 15.229  1    15.605 ? 1401 FAD A "C1'"  1 ? 
HETATM 5148 C "C2'"  . FAD B 2 .   ? 6.753   -24.685 16.472  1    14.503 ? 1401 FAD A "C2'"  1 ? 
HETATM 5149 O "O2'"  . FAD B 2 .   ? 7.451   -25.9   16.199  1    14.246 ? 1401 FAD A "O2'"  1 ? 
HETATM 5150 C "C3'"  . FAD B 2 .   ? 5.283   -24.906 16.851  1    14.042 ? 1401 FAD A "C3'"  1 ? 
HETATM 5151 O "O3'"  . FAD B 2 .   ? 4.547   -25.385 15.71   1    16.219 ? 1401 FAD A "O3'"  1 ? 
HETATM 5152 C "C4'"  . FAD B 2 .   ? 4.564   -23.655 17.366  1    14.706 ? 1401 FAD A "C4'"  1 ? 
HETATM 5153 O "O4'"  . FAD B 2 .   ? 5.279   -23.065 18.449  1    13.78  ? 1401 FAD A "O4'"  1 ? 
HETATM 5154 C "C5'"  . FAD B 2 .   ? 3.124   -23.857 17.8    1    12.712 ? 1401 FAD A "C5'"  1 ? 
HETATM 5155 O "O5'"  . FAD B 2 .   ? 3.038   -25.011 18.673  1    13.05  ? 1401 FAD A "O5'"  1 ? 
HETATM 5156 P P      . FAD B 2 .   ? 2.019   -25.058 19.905  1    14.26  ? 1401 FAD A P      1 ? 
HETATM 5157 O O1P    . FAD B 2 .   ? 2.332   -26.301 20.646  1    12.845 ? 1401 FAD A O1P    1 ? 
HETATM 5158 O O2P    . FAD B 2 .   ? 1.966   -23.776 20.638  1    13.221 ? 1401 FAD A O2P    1 ? 
HETATM 5159 O O3P    . FAD B 2 .   ? 0.626   -25.203 19.109  1    14.651 ? 1401 FAD A O3P    1 ? 
HETATM 5160 H H51A   . FAD B 2 .   ? -1.354  -26.077 16.052  1    20.437 ? 1401 FAD A H51A   1 c 
HETATM 5161 H H52A   . FAD B 2 .   ? -0.172  -24.915 16.657  1    20.415 ? 1401 FAD A H52A   1 c 
HETATM 5162 H H4B    . FAD B 2 .   ? -1.959  -23.727 15.386  1    21.849 ? 1401 FAD A H4B    1 c 
HETATM 5163 H H3B    . FAD B 2 .   ? -1.165  -22.856 17.989  1    22.274 ? 1401 FAD A H3B    1 c 
HETATM 5164 H HO3A   . FAD B 2 .   ? -1.553  -21.631 16.06   1    24.484 ? 1401 FAD A HO3A   1 ? 
HETATM 5165 H H2B    . FAD B 2 .   ? -3.226  -23.715 19.077  1    23.96  ? 1401 FAD A H2B    1 c 
HETATM 5166 H HO2A   . FAD B 2 .   ? -4.271  -21.901 19.496  1    25.559 ? 1401 FAD A HO2A   1 ? 
HETATM 5167 H H1B    . FAD B 2 .   ? -4.636  -22.877 16.459  1    24.401 ? 1401 FAD A H1B    1 c 
HETATM 5168 H H8A    . FAD B 2 .   ? -4.636  -25.78  19.014  1    27.704 ? 1401 FAD A H8A    1 c 
HETATM 5169 H H61A   . FAD B 2 .   ? -9.344  -26.538 18.88   1    29.088 ? 1401 FAD A H61A   1 ? 
HETATM 5170 H H62A   . FAD B 2 .   ? -10.746 -25.788 18.01   1    29.472 ? 1401 FAD A H62A   1 ? 
HETATM 5171 H H2A    . FAD B 2 .   ? -8.97   -22.516 15.567  1    28.364 ? 1401 FAD A H2A    1 c 
HETATM 5172 H HN3    . FAD B 2 .   ? 10.122  -19.547 17.742  1    18.52  ? 1401 FAD A HN3    1 ? 
HETATM 5173 H H6     . FAD B 2 .   ? 12.478  -24.442 13.647  1    16.485 ? 1401 FAD A H6     1 c 
HETATM 5174 H HM71   . FAD B 2 .   ? 11.993  -27.627 12.475  1    16.967 ? 1401 FAD A HM71   1 c 
HETATM 5175 H HM72   . FAD B 2 .   ? 12.974  -26.164 12.17   1    16.977 ? 1401 FAD A HM72   1 c 
HETATM 5176 H HM73   . FAD B 2 .   ? 11.719  -26.636 11.038  1    16.977 ? 1401 FAD A HM73   1 c 
HETATM 5177 H HM81   . FAD B 2 .   ? 9.555   -27.257 11.051  1    17.357 ? 1401 FAD A HM81   1 c 
HETATM 5178 H HM82   . FAD B 2 .   ? 8.037   -27.287 11.99   1    17.28  ? 1401 FAD A HM82   1 c 
HETATM 5179 H HM83   . FAD B 2 .   ? 9.414   -28.245 12.511  1    17.283 ? 1401 FAD A HM83   1 c 
HETATM 5180 H H9     . FAD B 2 .   ? 7.668   -25.636 13.541  1    15.594 ? 1401 FAD A H9     1 c 
HETATM 5181 H "H1'1" . FAD B 2 .   ? 6.461   -24.285 14.326  1    15.502 ? 1401 FAD A "H1'1" 1 c 
HETATM 5182 H "H1'2" . FAD B 2 .   ? 6.237   -22.91  15.351  1    15.415 ? 1401 FAD A "H1'2" 1 c 
HETATM 5183 H "H2'"  . FAD B 2 .   ? 7.267   -24.206 17.309  1    14.562 ? 1401 FAD A "H2'"  1 c 
HETATM 5184 H "HO2'" A FAD B 2 .   ? 7.976   -26.201 16.944  0.5  14.362 ? 1401 FAD A "HO2'" 1 ? 
HETATM 5185 H "H3'"  . FAD B 2 .   ? 5.237   -25.675 17.627  1    14.627 ? 1401 FAD A "H3'"  1 c 
HETATM 5186 H "HO3'" . FAD B 2 .   ? 3.865   -26.023 15.98   1    14.899 ? 1401 FAD A "HO3'" 1 ? 
HETATM 5187 H "H4'"  . FAD B 2 .   ? 4.556   -22.906 16.571  1    14.042 ? 1401 FAD A "H4'"  1 c 
HETATM 5188 H "HO4'" . FAD B 2 .   ? 5.201   -22.08  18.307  1    12.701 ? 1401 FAD A "HO4'" 1 ? 
HETATM 5189 H "H5'1" . FAD B 2 .   ? 2.471   -24.066 16.949  1    13.188 ? 1401 FAD A "H5'1" 1 c 
HETATM 5190 H "H5'2" . FAD B 2 .   ? 2.747   -22.953 18.286  1    13.193 ? 1401 FAD A "H5'2" 1 c 
HETATM 5191 O O1     . MES C 3 .   ? 5.439   -24.502 -2.847  1    36.888 ? 1402 MES A O1     1 ? 
HETATM 5192 C C2     . MES C 3 .   ? 5.921   -24.074 -1.575  1    33.694 ? 1402 MES A C2     1 ? 
HETATM 5193 C C3     . MES C 3 .   ? 6.997   -24.993 -1.05   1    34.195 ? 1402 MES A C3     1 ? 
HETATM 5194 N N4     . MES C 3 .   ? 7.636   -25.711 -2.2    1    36.349 ? 1402 MES A N4     1 ? 
HETATM 5195 C C5     . MES C 3 .   ? 6.621   -26.624 -2.824  1    32.983 ? 1402 MES A C5     1 ? 
HETATM 5196 C C6     . MES C 3 .   ? 5.29    -25.917 -2.902  1    32.773 ? 1402 MES A C6     1 ? 
HETATM 5197 C C7     . MES C 3 .   ? 8.92    -26.382 -1.78   1    38.667 ? 1402 MES A C7     1 ? 
HETATM 5198 C C8     . MES C 3 .   ? 9.375   -27.497 -2.71   1    43.962 ? 1402 MES A C8     1 ? 
HETATM 5199 S S      . MES C 3 .   ? 11.121  -27.442 -3.02   1    41.316 ? 1402 MES A S      1 ? 
HETATM 5200 O O1S    . MES C 3 .   ? 11.336  -27.915 -4.366  1    41.765 ? 1402 MES A O1S    1 ? 
HETATM 5201 O O2S    . MES C 3 .   ? 11.702  -28.294 -2.015  1    41.521 ? 1402 MES A O2S    1 ? 
HETATM 5202 O O3S    . MES C 3 .   ? 11.492  -26.065 -2.867  1    45.218 ? 1402 MES A O3S    1 ? 
HETATM 5203 H H21    . MES C 3 .   ? 5.092   -24.049 -0.869  1    34.589 ? 1402 MES A H21    1 c 
HETATM 5204 H H22    . MES C 3 .   ? 6.322   -23.066 -1.667  1    34.59  ? 1402 MES A H22    1 c 
HETATM 5205 H H31    . MES C 3 .   ? 6.567   -25.724 -0.366  1    34.55  ? 1402 MES A H31    1 c 
HETATM 5206 H H32    . MES C 3 .   ? 7.756   -24.42  -0.52   1    34.55  ? 1402 MES A H32    1 c 
HETATM 5207 H H51    . MES C 3 .   ? 6.532   -27.524 -2.218  1    33.677 ? 1402 MES A H51    1 c 
HETATM 5208 H H52    . MES C 3 .   ? 6.951   -26.906 -3.822  1    33.768 ? 1402 MES A H52    1 c 
HETATM 5209 H H61    . MES C 3 .   ? 4.792   -26.187 -3.832  1    33.732 ? 1402 MES A H61    1 c 
HETATM 5210 H H62    . MES C 3 .   ? 4.661   -26.24  -2.075  1    33.734 ? 1402 MES A H62    1 c 
HETATM 5211 H H71    . MES C 3 .   ? 8.764   -26.768 -0.776  1    39.206 ? 1402 MES A H71    1 c 
HETATM 5212 H H72    . MES C 3 .   ? 9.677   -25.605 -1.719  1    39.239 ? 1402 MES A H72    1 c 
HETATM 5213 H H81    . MES C 3 .   ? 8.875   -27.444 -3.67   1    42.064 ? 1402 MES A H81    1 c 
HETATM 5214 H H82    . MES C 3 .   ? 9.151   -28.469 -2.28   1    42.184 ? 1402 MES A H82    1 c 
HETATM 5215 O O      . HOH D 4 .   ? -0.764  -29.039 17.361  1    33.577 ? 1501 HOH A O      1 ? 
HETATM 5216 H H1     . HOH D 4 .   ? -0.116  -29.736 17.591  1    32.27  ? 1501 HOH A H1     1 ? 
HETATM 5217 H H2     . HOH D 4 .   ? -1.287  -29.339 16.589  1    31.835 ? 1501 HOH A H2     1 ? 
HETATM 5218 O O      . HOH D 4 .   ? 26.379  -7.024  18.89   1    46.053 ? 1502 HOH A O      1 ? 
HETATM 5219 H H1     . HOH D 4 .   ? 27.257  -6.591  18.894  1    45.681 ? 1502 HOH A H1     1 ? 
HETATM 5220 H H2     . HOH D 4 .   ? 25.774  -6.471  18.347  1    44.322 ? 1502 HOH A H2     1 ? 
HETATM 5221 O O      . HOH D 4 .   ? 35.71   -22.778 8.382   1    27.286 ? 1503 HOH A O      1 ? 
HETATM 5222 H H1     . HOH D 4 .   ? 36.31   -22.819 9.142   1    25.653 ? 1503 HOH A H1     1 ? 
HETATM 5223 H H2     . HOH D 4 .   ? 35.89   -21.932 7.93    1    26.807 ? 1503 HOH A H2     1 ? 
HETATM 5224 O O      . HOH D 4 .   ? 13.642  -26.436 3.146   1    37.981 ? 1504 HOH A O      1 ? 
HETATM 5225 H H1     . HOH D 4 .   ? 14.454  -26.627 2.64    1    33.452 ? 1504 HOH A H1     1 ? 
HETATM 5226 H H2     . HOH D 4 .   ? 13.883  -26.34  4.088   1    37.677 ? 1504 HOH A H2     1 ? 
HETATM 5227 O O      . HOH D 4 .   ? 16.649  -30.054 34.699  1    43.273 ? 1505 HOH A O      1 ? 
HETATM 5228 H H1     . HOH D 4 .   ? 16.633  -31.045 34.674  1    37.503 ? 1505 HOH A H1     1 ? 
HETATM 5229 H H2     . HOH D 4 .   ? 17.546  -29.694 34.459  1    44.358 ? 1505 HOH A H2     1 ? 
HETATM 5230 O O      . HOH D 4 .   ? 33.69   -14.798 28.069  1    23.594 ? 1506 HOH A O      1 ? 
HETATM 5231 H H1     . HOH D 4 .   ? 33.284  -15.112 27.239  1    23.104 ? 1506 HOH A H1     1 ? 
HETATM 5232 H H2     . HOH D 4 .   ? 33.149  -14.045 28.392  1    22.486 ? 1506 HOH A H2     1 ? 
HETATM 5233 O O      . HOH D 4 .   ? 11.408  -19.355 39.283  1    24.857 ? 1507 HOH A O      1 ? 
HETATM 5234 H H1     . HOH D 4 .   ? 11.865  -18.633 38.824  1    24.995 ? 1507 HOH A H1     1 ? 
HETATM 5235 H H2     . HOH D 4 .   ? 10.768  -18.936 39.879  1    26.584 ? 1507 HOH A H2     1 ? 
HETATM 5236 O O      . HOH D 4 .   ? 10.781  -2.478  -2.872  1    38.015 ? 1508 HOH A O      1 ? 
HETATM 5237 H H1     . HOH D 4 .   ? 11.738  -2.305  -2.77   1    34.596 ? 1508 HOH A H1     1 ? 
HETATM 5238 H H2     . HOH D 4 .   ? 10.304  -1.966  -2.184  1    38.824 ? 1508 HOH A H2     1 ? 
HETATM 5239 O O      . HOH D 4 .   ? 3.737   -34.47  27.655  1    21.471 ? 1509 HOH A O      1 ? 
HETATM 5240 H H1     . HOH D 4 .   ? 4.1     -34.315 26.767  1    22.342 ? 1509 HOH A H1     1 ? 
HETATM 5241 H H2     . HOH D 4 .   ? 2.867   -34.823 27.531  1    18.565 ? 1509 HOH A H2     1 ? 
HETATM 5242 O O      . HOH D 4 .   ? 19.304  -1.378  9.399   1    40.149 ? 1510 HOH A O      1 ? 
HETATM 5243 H H1     . HOH D 4 .   ? 20.12   -1.808  9.069   1    38.838 ? 1510 HOH A H1     1 ? 
HETATM 5244 H H2     . HOH D 4 .   ? 19.534  -0.81   10.163  1    38.011 ? 1510 HOH A H2     1 ? 
HETATM 5245 O O      . HOH D 4 .   ? 7.349   -12.445 3.127   1    26.51  ? 1511 HOH A O      1 ? 
HETATM 5246 H H1     . HOH D 4 .   ? 7.496   -13.177 2.491   1    26.809 ? 1511 HOH A H1     1 ? 
HETATM 5247 H H2     . HOH D 4 .   ? 7.569   -11.585 2.711   1    24.481 ? 1511 HOH A H2     1 ? 
HETATM 5248 O O      . HOH D 4 .   ? 39.384  -23.717 17.918  1    27.131 ? 1512 HOH A O      1 ? 
HETATM 5249 H H1     . HOH D 4 .   ? 39.441  -24.324 18.666  1    25.493 ? 1512 HOH A H1     1 ? 
HETATM 5250 H H2     . HOH D 4 .   ? 38.653  -23.088 18.113  1    26.535 ? 1512 HOH A H2     1 ? 
HETATM 5251 O O      . HOH D 4 .   ? 37.934  -14.895 7.023   1    29.141 ? 1513 HOH A O      1 ? 
HETATM 5252 H H1     . HOH D 4 .   ? 38.233  -14.378 6.253   1    28.174 ? 1513 HOH A H1     1 ? 
HETATM 5253 H H2     . HOH D 4 .   ? 38.426  -14.597 7.801   1    26.702 ? 1513 HOH A H2     1 ? 
HETATM 5254 O O      . HOH D 4 .   ? 16.797  -26.464 12.258  1    30.463 ? 1514 HOH A O      1 ? 
HETATM 5255 H H1     . HOH D 4 .   ? 16.19   -25.713 12.143  1    28.247 ? 1514 HOH A H1     1 ? 
HETATM 5256 H H2     . HOH D 4 .   ? 17.679  -26.095 12.481  1    28.999 ? 1514 HOH A H2     1 ? 
HETATM 5257 O O      . HOH D 4 .   ? 36.525  -2.770  2.243   1    23.947 ? 1515 HOH A O      1 ? 
HETATM 5258 H H1     . HOH D 4 .   ? 37.145  -3.382  1.827   1    26.382 ? 1515 HOH A H1     1 ? 
HETATM 5259 H H2     . HOH D 4 .   ? 35.714  -2.865  1.729   1    26.047 ? 1515 HOH A H2     1 ? 
HETATM 5260 O O      . HOH D 4 .   ? 34.255  -5.053  9.673   1    18.514 ? 1516 HOH A O      1 ? 
HETATM 5261 H H1     . HOH D 4 .   ? 34.183  -5.507  8.816   1    18.483 ? 1516 HOH A H1     1 ? 
HETATM 5262 H H2     . HOH D 4 .   ? 34.303  -4.102  9.487   1    17.531 ? 1516 HOH A H2     1 ? 
HETATM 5263 O O      . HOH D 4 .   ? 0.443   -33.521 21.626  1    24.283 ? 1517 HOH A O      1 ? 
HETATM 5264 H H1     . HOH D 4 .   ? -0.042  -32.849 22.134  1    23.84  ? 1517 HOH A H1     1 ? 
HETATM 5265 H H2     . HOH D 4 .   ? -0.026  -33.629 20.782  1    23.622 ? 1517 HOH A H2     1 ? 
HETATM 5266 O O      . HOH D 4 .   ? 21.955  -11.579 -12.195 1    31.276 ? 1518 HOH A O      1 ? 
HETATM 5267 H H1     . HOH D 4 .   ? 22.725  -12.009 -11.805 1    31.816 ? 1518 HOH A H1     1 ? 
HETATM 5268 H H2     . HOH D 4 .   ? 21.927  -11.891 -13.115 1    35.474 ? 1518 HOH A H2     1 ? 
HETATM 5269 O O      . HOH D 4 .   ? 16.85   -0.44   5.169   1    22.245 ? 1519 HOH A O      1 ? 
HETATM 5270 H H1     . HOH D 4 .   ? 17.703  -0.852  4.93    1    21.524 ? 1519 HOH A H1     1 ? 
HETATM 5271 H H2     . HOH D 4 .   ? 16.931  0.526   5.044   1    21.5   ? 1519 HOH A H2     1 ? 
HETATM 5272 O O      . HOH D 4 .   ? 1.707   -15.992 2.288   1    32.575 ? 1520 HOH A O      1 ? 
HETATM 5273 H H1     . HOH D 4 .   ? 1.384   -15.603 3.132   1    29.801 ? 1520 HOH A H1     1 ? 
HETATM 5274 H H2     . HOH D 4 .   ? 1.146   -16.762 2.05    1    31.758 ? 1520 HOH A H2     1 ? 
HETATM 5275 O O      . HOH D 4 .   ? 32.561  -14.847 -6.18   1    39.491 ? 1521 HOH A O      1 ? 
HETATM 5276 H H1     . HOH D 4 .   ? 32.668  -14.437 -7.066  1    39.891 ? 1521 HOH A H1     1 ? 
HETATM 5277 H H2     . HOH D 4 .   ? 32.471  -14.139 -5.511  1    38.64  ? 1521 HOH A H2     1 ? 
HETATM 5278 O O      . HOH D 4 .   ? -3.514  -32.79  26.838  1    32.548 ? 1522 HOH A O      1 ? 
HETATM 5279 H H1     . HOH D 4 .   ? -2.905  -33.541 26.706  1    30.745 ? 1522 HOH A H1     1 ? 
HETATM 5280 H H2     . HOH D 4 .   ? -4.42   -33.146 26.855  1    32.192 ? 1522 HOH A H2     1 ? 
HETATM 5281 O O      . HOH D 4 .   ? 11.321  0.44    -1.29   1    41.837 ? 1523 HOH A O      1 ? 
HETATM 5282 H H1     . HOH D 4 .   ? 11.619  0.93    -0.503  1    40.273 ? 1523 HOH A H1     1 ? 
HETATM 5283 H H2     . HOH D 4 .   ? 10.356  0.355   -1.23   1    40.329 ? 1523 HOH A H2     1 ? 
HETATM 5284 O O      . HOH D 4 .   ? 8.474   -3.459  -3.547  1    33.074 ? 1524 HOH A O      1 ? 
HETATM 5285 H H1     . HOH D 4 .   ? 8.092   -2.984  -4.303  1    33.758 ? 1524 HOH A H1     1 ? 
HETATM 5286 H H2     . HOH D 4 .   ? 8.374   -2.898  -2.753  1    31.92  ? 1524 HOH A H2     1 ? 
HETATM 5287 O O      . HOH D 4 .   ? 9.108   -18.653 -11.618 1    44.345 ? 1525 HOH A O      1 ? 
HETATM 5288 H H1     . HOH D 4 .   ? 8.668   -19.041 -12.401 1    46.347 ? 1525 HOH A H1     1 ? 
HETATM 5289 H H2     . HOH D 4 .   ? 8.427   -18.259 -11.041 1    42.572 ? 1525 HOH A H2     1 ? 
HETATM 5290 O O      . HOH D 4 .   ? 16.34   -40.535 24.71   1    22.639 ? 1526 HOH A O      1 ? 
HETATM 5291 H H1     . HOH D 4 .   ? 17.247  -40.657 24.409  1    20.381 ? 1526 HOH A H1     1 ? 
HETATM 5292 H H2     . HOH D 4 .   ? 16.371  -39.916 25.464  1    23.312 ? 1526 HOH A H2     1 ? 
HETATM 5293 O O      . HOH D 4 .   ? 17.888  -18.408 36.462  1    40.618 ? 1527 HOH A O      1 ? 
HETATM 5294 H H1     . HOH D 4 .   ? 17.583  -18.395 37.388  1    37.972 ? 1527 HOH A H1     1 ? 
HETATM 5295 H H2     . HOH D 4 .   ? 17.38   -17.725 35.972  1    41.442 ? 1527 HOH A H2     1 ? 
HETATM 5296 O O      . HOH D 4 .   ? 1.934   -14.127 19.691  1    26.927 ? 1528 HOH A O      1 ? 
HETATM 5297 H H1     . HOH D 4 .   ? 2.494   -13.502 20.208  1    26.949 ? 1528 HOH A H1     1 ? 
HETATM 5298 H H2     . HOH D 4 .   ? 2.007   -15.022 20.082  1    24.088 ? 1528 HOH A H2     1 ? 
HETATM 5299 O O      . HOH D 4 .   ? 4.413   -15.144 -8.498  1    29.889 ? 1529 HOH A O      1 ? 
HETATM 5300 H H1     . HOH D 4 .   ? 5.336   -15.312 -8.228  1    28.437 ? 1529 HOH A H1     1 ? 
HETATM 5301 H H2     . HOH D 4 .   ? 4.297   -14.182 -8.562  1    27.899 ? 1529 HOH A H2     1 ? 
HETATM 5302 O O      . HOH D 4 .   ? 27.899  -10.983 -9.567  1    23.873 ? 1530 HOH A O      1 ? 
HETATM 5303 H H1     . HOH D 4 .   ? 28.131  -11.182 -8.641  1    24.068 ? 1530 HOH A H1     1 ? 
HETATM 5304 H H2     . HOH D 4 .   ? 28.7    -11.176 -10.081 1    23.577 ? 1530 HOH A H2     1 ? 
HETATM 5305 O O      . HOH D 4 .   ? 10.120  -28.802 -0.173  1    56.266 ? 1531 HOH A O      1 ? 
HETATM 5306 H H1     . HOH D 4 .   ? 11.005  -28.728 -0.598  1    52.961 ? 1531 HOH A H1     1 ? 
HETATM 5307 H H2     . HOH D 4 .   ? 10.202  -28.702 0.799   1    49.919 ? 1531 HOH A H2     1 ? 
HETATM 5308 O O      . HOH D 4 .   ? 16.344  -11.279 -21.196 1    18.68  ? 1532 HOH A O      1 ? 
HETATM 5309 H H1     . HOH D 4 .   ? 17.061  -10.995 -20.613 1    19.441 ? 1532 HOH A H1     1 ? 
HETATM 5310 H H2     . HOH D 4 .   ? 16.324  -10.685 -21.971 1    19.351 ? 1532 HOH A H2     1 ? 
HETATM 5311 O O      . HOH D 4 .   ? 15.135  -36.619 19.119  1    22.601 ? 1533 HOH A O      1 ? 
HETATM 5312 H H1     . HOH D 4 .   ? 15.199  -37.416 18.606  1    24.403 ? 1533 HOH A H1     1 ? 
HETATM 5313 H H2     . HOH D 4 .   ? 14.752  -35.977 18.502  1    23.396 ? 1533 HOH A H2     1 ? 
HETATM 5314 O O      . HOH D 4 .   ? -4.76   -26.111 22.327  1    53.046 ? 1534 HOH A O      1 ? 
HETATM 5315 H H1     . HOH D 4 .   ? -4.528  -25.782 21.438  1    47.71  ? 1534 HOH A H1     1 ? 
HETATM 5316 H H2     . HOH D 4 .   ? -4.428  -25.462 22.978  1    51.479 ? 1534 HOH A H2     1 ? 
HETATM 5317 O O      . HOH D 4 .   ? 19.957  -0.542  6.139   1    29.93  ? 1535 HOH A O      1 ? 
HETATM 5318 H H1     . HOH D 4 .   ? 19.983  -0.71   5.175   1    29.162 ? 1535 HOH A H1     1 ? 
HETATM 5319 H H2     . HOH D 4 .   ? 20.803  -0.121  6.387   1    29.476 ? 1535 HOH A H2     1 ? 
HETATM 5320 O O      . HOH D 4 .   ? -13.323 -16.509 25.91   1    43.405 ? 1536 HOH A O      1 ? 
HETATM 5321 H H1     . HOH D 4 .   ? -12.476 -16.574 26.388  1    40.217 ? 1536 HOH A H1     1 ? 
HETATM 5322 H H2     . HOH D 4 .   ? -13.605 -15.577 25.928  1    43.115 ? 1536 HOH A H2     1 ? 
HETATM 5323 O O      . HOH D 4 .   ? 13.934  -8.9    26.264  1    32.283 ? 1537 HOH A O      1 ? 
HETATM 5324 H H1     . HOH D 4 .   ? 14.305  -8.4    25.513  1    30.275 ? 1537 HOH A H1     1 ? 
HETATM 5325 H H2     . HOH D 4 .   ? 12.978  -9.022  26.097  1    30.928 ? 1537 HOH A H2     1 ? 
HETATM 5326 O O      . HOH D 4 .   ? 14.954  -26.626 39.021  1    33.357 ? 1538 HOH A O      1 ? 
HETATM 5327 H H1     . HOH D 4 .   ? 15.658  -26.183 39.547  1    33.791 ? 1538 HOH A H1     1 ? 
HETATM 5328 H H2     . HOH D 4 .   ? 14.064  -26.331 39.317  1    31.264 ? 1538 HOH A H2     1 ? 
HETATM 5329 O O      . HOH D 4 .   ? 28.02   -22.669 12.999  1    21.643 ? 1539 HOH A O      1 ? 
HETATM 5330 H H1     . HOH D 4 .   ? 28.625  -23.007 12.307  1    19.568 ? 1539 HOH A H1     1 ? 
HETATM 5331 H H2     . HOH D 4 .   ? 28.094  -23.214 13.816  1    19.333 ? 1539 HOH A H2     1 ? 
HETATM 5332 O O      . HOH D 4 .   ? -21.734 -12.306 12.224  1    35.215 ? 1540 HOH A O      1 ? 
HETATM 5333 H H1     . HOH D 4 .   ? -22.011 -12.743 11.386  1    34.126 ? 1540 HOH A H1     1 ? 
HETATM 5334 H H2     . HOH D 4 .   ? -22.327 -12.568 12.965  1    37.357 ? 1540 HOH A H2     1 ? 
HETATM 5335 O O      . HOH D 4 .   ? 25.281  -21.907 32.771  1    28.414 ? 1541 HOH A O      1 ? 
HETATM 5336 H H1     . HOH D 4 .   ? 25.956  -22.074 32.09   1    26.562 ? 1541 HOH A H1     1 ? 
HETATM 5337 H H2     . HOH D 4 .   ? 25.15   -22.733 33.275  1    26.782 ? 1541 HOH A H2     1 ? 
HETATM 5338 O O      . HOH D 4 .   ? 4.2     -24.061 12.4    1    26.266 ? 1542 HOH A O      1 ? 
HETATM 5339 H H1     . HOH D 4 .   ? 4.288   -23.828 11.456  1    26.024 ? 1542 HOH A H1     1 ? 
HETATM 5340 H H2     . HOH D 4 .   ? 4.947   -24.641 12.616  1    24.884 ? 1542 HOH A H2     1 ? 
HETATM 5341 O O      . HOH D 4 .   ? 6.882   -16.867 32.187  1    23.807 ? 1543 HOH A O      1 ? 
HETATM 5342 H H1     . HOH D 4 .   ? 7.004   -16.555 31.275  1    21.579 ? 1543 HOH A H1     1 ? 
HETATM 5343 H H2     . HOH D 4 .   ? 7.737   -17.223 32.492  1    23.652 ? 1543 HOH A H2     1 ? 
HETATM 5344 O O      . HOH D 4 .   ? 25.595  -24.691 24.839  1    14.261 ? 1544 HOH A O      1 ? 
HETATM 5345 H H1     . HOH D 4 .   ? 25.687  -24.709 23.896  1    14.41  ? 1544 HOH A H1     1 ? 
HETATM 5346 H H2     . HOH D 4 .   ? 24.782  -24.204 24.959  1    14.929 ? 1544 HOH A H2     1 ? 
HETATM 5347 O O      . HOH D 4 .   ? 23.717  -30.119 -5.73   1    37.803 ? 1545 HOH A O      1 ? 
HETATM 5348 H H1     . HOH D 4 .   ? 23.443  -29.187 -5.653  1    37.771 ? 1545 HOH A H1     1 ? 
HETATM 5349 H H2     . HOH D 4 .   ? 23.892  -30.293 -6.671  1    35.811 ? 1545 HOH A H2     1 ? 
HETATM 5350 O O      . HOH D 4 .   ? 5.002   -20.457 18.225  1    12.875 ? 1546 HOH A O      1 ? 
HETATM 5351 H H1     . HOH D 4 .   ? 5.92    -20.294 18.025  1    13.121 ? 1546 HOH A H1     1 ? 
HETATM 5352 H H2     . HOH D 4 .   ? 4.721   -19.648 18.705  1    13.446 ? 1546 HOH A H2     1 ? 
HETATM 5353 O O      . HOH D 4 .   ? 24.526  -13.484 26.284  1    12.131 ? 1547 HOH A O      1 ? 
HETATM 5354 H H1     . HOH D 4 .   ? 25.131  -12.77  26.476  1    13.008 ? 1547 HOH A H1     1 ? 
HETATM 5355 H H2     . HOH D 4 .   ? 24.89   -14.194 26.822  1    13.16  ? 1547 HOH A H2     1 ? 
HETATM 5356 O O      . HOH D 4 .   ? 37.751  -22.281 1.855   1    41.474 ? 1548 HOH A O      1 ? 
HETATM 5357 H H1     . HOH D 4 .   ? 37.78   -21.339 2.114   1    39.76  ? 1548 HOH A H1     1 ? 
HETATM 5358 H H2     . HOH D 4 .   ? 37.449  -22.332 0.922   1    39.651 ? 1548 HOH A H2     1 ? 
HETATM 5359 O O      . HOH D 4 .   ? 21.292  -18.962 -9.966  1    39.542 ? 1549 HOH A O      1 ? 
HETATM 5360 H H1     . HOH D 4 .   ? 21.413  -19.485 -10.774 1    39.552 ? 1549 HOH A H1     1 ? 
HETATM 5361 H H2     . HOH D 4 .   ? 21.697  -18.091 -10.133 1    39.574 ? 1549 HOH A H2     1 ? 
HETATM 5362 O O      . HOH D 4 .   ? 25.302  -36.249 12.537  1    37.728 ? 1550 HOH A O      1 ? 
HETATM 5363 H H1     . HOH D 4 .   ? 25.961  -35.652 12.94   1    35.177 ? 1550 HOH A H1     1 ? 
HETATM 5364 H H2     . HOH D 4 .   ? 25.469  -36.273 11.575  1    37.778 ? 1550 HOH A H2     1 ? 
HETATM 5365 O O      . HOH D 4 .   ? 13.331  -37.899 30.608  1    41.319 ? 1551 HOH A O      1 ? 
HETATM 5366 H H1     . HOH D 4 .   ? 13.948  -37.155 30.501  1    40.877 ? 1551 HOH A H1     1 ? 
HETATM 5367 H H2     . HOH D 4 .   ? 12.664  -37.622 31.26   1    38.646 ? 1551 HOH A H2     1 ? 
HETATM 5368 O O      . HOH D 4 .   ? 20.543  -8.451  -16.305 1    36.426 ? 1552 HOH A O      1 ? 
HETATM 5369 H H1     . HOH D 4 .   ? 20.548  -7.795  -15.581 1    35.064 ? 1552 HOH A H1     1 ? 
HETATM 5370 H H2     . HOH D 4 .   ? 19.82   -8.213  -16.926 1    38.523 ? 1552 HOH A H2     1 ? 
HETATM 5371 O O      . HOH D 4 .   ? 20.705  -11.182 21.979  1    15.701 ? 1553 HOH A O      1 ? 
HETATM 5372 H H1     . HOH D 4 .   ? 21.552  -10.717 21.921  1    15.937 ? 1553 HOH A H1     1 ? 
HETATM 5373 H H2     . HOH D 4 .   ? 20.118  -10.637 22.513  1    14.362 ? 1553 HOH A H2     1 ? 
HETATM 5374 O O      . HOH D 4 .   ? 19.909  -27.18  -2.998  1    29.29  ? 1554 HOH A O      1 ? 
HETATM 5375 H H1     . HOH D 4 .   ? 20.541  -27.636 -3.604  1    27.797 ? 1554 HOH A H1     1 ? 
HETATM 5376 H H2     . HOH D 4 .   ? 19.083  -27.702 -2.895  1    27.549 ? 1554 HOH A H2     1 ? 
HETATM 5377 O O      . HOH D 4 .   ? 7.939   -15.888 10.816  1    33.413 ? 1555 HOH A O      1 ? 
HETATM 5378 H H1     . HOH D 4 .   ? 7.498   -15.606 11.644  1    33.075 ? 1555 HOH A H1     1 ? 
HETATM 5379 H H2     . HOH D 4 .   ? 7.608   -15.325 10.102  1    33.123 ? 1555 HOH A H2     1 ? 
HETATM 5380 O O      . HOH D 4 .   ? 9.868   -26.696 8.689   1    39.179 ? 1556 HOH A O      1 ? 
HETATM 5381 H H1     . HOH D 4 .   ? 10.74   -27.125 8.576   1    36.084 ? 1556 HOH A H1     1 ? 
HETATM 5382 H H2     . HOH D 4 .   ? 9.879   -25.847 8.2     1    38.494 ? 1556 HOH A H2     1 ? 
HETATM 5383 O O      . HOH D 4 .   ? 26.679  -16.678 22.677  1    18.448 ? 1557 HOH A O      1 ? 
HETATM 5384 H H1     . HOH D 4 .   ? 27.541  -16.772 22.242  1    19.088 ? 1557 HOH A H1     1 ? 
HETATM 5385 H H2     . HOH D 4 .   ? 26.75   -16.957 23.61   1    18.732 ? 1557 HOH A H2     1 ? 
HETATM 5386 O O      . HOH D 4 .   ? 41.079  -19.534 12.055  1    37.112 ? 1558 HOH A O      1 ? 
HETATM 5387 H H1     . HOH D 4 .   ? 40.565  -20.181 11.544  1    38.271 ? 1558 HOH A H1     1 ? 
HETATM 5388 H H2     . HOH D 4 .   ? 40.618  -19.456 12.918  1    39.796 ? 1558 HOH A H2     1 ? 
HETATM 5389 O O      . HOH D 4 .   ? -14.583 -19.144 18.519  1    46.56  ? 1559 HOH A O      1 ? 
HETATM 5390 H H1     . HOH D 4 .   ? -14.909 -19.994 18.165  1    44.985 ? 1559 HOH A H1     1 ? 
HETATM 5391 H H2     . HOH D 4 .   ? -14.885 -18.439 17.907  1    42.172 ? 1559 HOH A H2     1 ? 
HETATM 5392 O O      . HOH D 4 .   ? 15.698  -6.789  15.261  1    23.488 ? 1560 HOH A O      1 ? 
HETATM 5393 H H1     . HOH D 4 .   ? 15.52   -7.744  15.391  1    22.765 ? 1560 HOH A H1     1 ? 
HETATM 5394 H H2     . HOH D 4 .   ? 15.64   -6.603  14.308  1    22.719 ? 1560 HOH A H2     1 ? 
HETATM 5395 O O      . HOH D 4 .   ? 8.078   -9.879  15.54   1    27.349 ? 1561 HOH A O      1 ? 
HETATM 5396 H H1     . HOH D 4 .   ? 8.011   -10.795 15.842  1    27.334 ? 1561 HOH A H1     1 ? 
HETATM 5397 H H2     . HOH D 4 .   ? 8.354   -9.361  16.318  1    27.629 ? 1561 HOH A H2     1 ? 
HETATM 5398 O O      . HOH D 4 .   ? 21.992  -2.496  3.528   1    18.864 ? 1562 HOH A O      1 ? 
HETATM 5399 H H1     . HOH D 4 .   ? 22.621  -2.223  4.214   1    19.289 ? 1562 HOH A H1     1 ? 
HETATM 5400 H H2     . HOH D 4 .   ? 21.227  -2.915  3.998   1    18.761 ? 1562 HOH A H2     1 ? 
HETATM 5401 O O      . HOH D 4 .   ? 12.521  -28.691 8.717   1    26.918 ? 1563 HOH A O      1 ? 
HETATM 5402 H H1     . HOH D 4 .   ? 12.649  -28.231 7.87    1    27.992 ? 1563 HOH A H1     1 ? 
HETATM 5403 H H2     . HOH D 4 .   ? 12.778  -28.073 9.419   1    26.009 ? 1563 HOH A H2     1 ? 
HETATM 5404 O O      . HOH D 4 .   ? 12.694  1.948   2.581   1    40.083 ? 1564 HOH A O      1 ? 
HETATM 5405 H H1     . HOH D 4 .   ? 13.383  2.433   3.073   1    38.06  ? 1564 HOH A H1     1 ? 
HETATM 5406 H H2     . HOH D 4 .   ? 12.742  2.225   1.65    1    37.411 ? 1564 HOH A H2     1 ? 
HETATM 5407 O O      . HOH D 4 .   ? 5.62    -11.02  18.976  1    21.88  ? 1565 HOH A O      1 ? 
HETATM 5408 H H1     . HOH D 4 .   ? 4.994   -10.586 19.6    1    21.667 ? 1565 HOH A H1     1 ? 
HETATM 5409 H H2     . HOH D 4 .   ? 5.571   -10.543 18.126  1    20.098 ? 1565 HOH A H2     1 ? 
HETATM 5410 O O      . HOH D 4 .   ? 7.895   -12.594 16.699  1    20.525 ? 1566 HOH A O      1 ? 
HETATM 5411 H H1     . HOH D 4 .   ? 8.253   -12.864 15.839  1    22.567 ? 1566 HOH A H1     1 ? 
HETATM 5412 H H2     . HOH D 4 .   ? 7.467   -13.382 17.069  1    23.352 ? 1566 HOH A H2     1 ? 
HETATM 5413 O O      . HOH D 4 .   ? 13.625  -4.451  -9.113  1    31.263 ? 1567 HOH A O      1 ? 
HETATM 5414 H H1     . HOH D 4 .   ? 14.122  -4.87   -9.829  1    32.405 ? 1567 HOH A H1     1 ? 
HETATM 5415 H H2     . HOH D 4 .   ? 14.132  -4.606  -8.303  1    32.517 ? 1567 HOH A H2     1 ? 
HETATM 5416 O O      . HOH D 4 .   ? 7.612   -38.616 25.606  1    31.551 ? 1568 HOH A O      1 ? 
HETATM 5417 H H1     . HOH D 4 .   ? 8.496   -38.395 25.976  1    31.594 ? 1568 HOH A H1     1 ? 
HETATM 5418 H H2     . HOH D 4 .   ? 7.612   -38.461 24.624  1    30.474 ? 1568 HOH A H2     1 ? 
HETATM 5419 O O      . HOH D 4 .   ? 5.808   0.112   16.818  1    21.814 ? 1569 HOH A O      1 ? 
HETATM 5420 H H1     . HOH D 4 .   ? 6.233   0.825   17.327  1    21.773 ? 1569 HOH A H1     1 ? 
HETATM 5421 H H2     . HOH D 4 .   ? 5.403   -0.458  17.488  1    22.213 ? 1569 HOH A H2     1 ? 
HETATM 5422 O O      . HOH D 4 .   ? 5.032   -17.361 -5.055  1    35.137 ? 1570 HOH A O      1 ? 
HETATM 5423 H H1     . HOH D 4 .   ? 5.058   -16.435 -4.736  1    36.573 ? 1570 HOH A H1     1 ? 
HETATM 5424 H H2     . HOH D 4 .   ? 4.145   -17.54  -5.411  1    32.82  ? 1570 HOH A H2     1 ? 
HETATM 5425 O O      . HOH D 4 .   ? 16.79   0.323   15.388  1    36.44  ? 1571 HOH A O      1 ? 
HETATM 5426 H H1     . HOH D 4 .   ? 17.267  -0.43   15.812  1    32.719 ? 1571 HOH A H1     1 ? 
HETATM 5427 H H2     . HOH D 4 .   ? 15.836  0.114   15.32   1    34.635 ? 1571 HOH A H2     1 ? 
HETATM 5428 O O      . HOH D 4 .   ? 13.273  -20.475 18.69   1    18.055 ? 1572 HOH A O      1 ? 
HETATM 5429 H H1     . HOH D 4 .   ? 13.746  -21.316 18.623  1    16.658 ? 1572 HOH A H1     1 ? 
HETATM 5430 H H2     . HOH D 4 .   ? 12.4    -20.623 18.292  1    18.786 ? 1572 HOH A H2     1 ? 
HETATM 5431 O O      . HOH D 4 .   ? 24.601  -3.125  -12.509 1    33.658 ? 1573 HOH A O      1 ? 
HETATM 5432 H H1     . HOH D 4 .   ? 25.522  -3.042  -12.220 1    31.91  ? 1573 HOH A H1     1 ? 
HETATM 5433 H H2     . HOH D 4 .   ? 24.551  -2.766  -13.420 1    33.935 ? 1573 HOH A H2     1 ? 
HETATM 5434 O O      . HOH D 4 .   ? 28.877  -34.506 17.002  1    30.515 ? 1574 HOH A O      1 ? 
HETATM 5435 H H1     . HOH D 4 .   ? 28.602  -34.005 16.211  1    27.614 ? 1574 HOH A H1     1 ? 
HETATM 5436 H H2     . HOH D 4 .   ? 28.519  -35.411 16.93   1    28.572 ? 1574 HOH A H2     1 ? 
HETATM 5437 O O      . HOH D 4 .   ? 12.801  -19.882 13.596  1    15.439 ? 1575 HOH A O      1 ? 
HETATM 5438 H H1     . HOH D 4 .   ? 13.15   -20.776 13.817  1    13.948 ? 1575 HOH A H1     1 ? 
HETATM 5439 H H2     . HOH D 4 .   ? 12.895  -19.215 14.334  1    14.331 ? 1575 HOH A H2     1 ? 
HETATM 5440 O O      . HOH D 4 .   ? 26.443  -6.859  -5.227  1    26.437 ? 1576 HOH A O      1 ? 
HETATM 5441 H H1     . HOH D 4 .   ? 27.302  -6.71   -4.83   1    24.895 ? 1576 HOH A H1     1 ? 
HETATM 5442 H H2     . HOH D 4 .   ? 25.865  -7.238  -4.546  1    26.414 ? 1576 HOH A H2     1 ? 
HETATM 5443 O O      . HOH D 4 .   ? 19.098  -22.747 14.992  1    17.304 ? 1577 HOH A O      1 ? 
HETATM 5444 H H1     . HOH D 4 .   ? 18.576  -22.02  15.33   1    17.327 ? 1577 HOH A H1     1 ? 
HETATM 5445 H H2     . HOH D 4 .   ? 18.492  -23.324 14.502  1    15.829 ? 1577 HOH A H2     1 ? 
HETATM 5446 O O      . HOH D 4 .   ? -1.525  -31.255 22.001  1    22.813 ? 1578 HOH A O      1 ? 
HETATM 5447 H H1     . HOH D 4 .   ? -1.271  -31.464 22.931  1    20.166 ? 1578 HOH A H1     1 ? 
HETATM 5448 H H2     . HOH D 4 .   ? -1.982  -30.39  21.984  1    20.645 ? 1578 HOH A H2     1 ? 
HETATM 5449 O O      . HOH D 4 .   ? 4.541   -11.728 2.199   1    44.621 ? 1579 HOH A O      1 ? 
HETATM 5450 H H1     . HOH D 4 .   ? 4.668   -11.373 3.101   1    44.797 ? 1579 HOH A H1     1 ? 
HETATM 5451 H H2     . HOH D 4 .   ? 3.708   -11.366 1.839   1    42.34  ? 1579 HOH A H2     1 ? 
HETATM 5452 O O      . HOH D 4 .   ? 33.487  -14.158 16.037  1    18.401 ? 1580 HOH A O      1 ? 
HETATM 5453 H H1     . HOH D 4 .   ? 32.985  -14.872 15.618  1    17.908 ? 1580 HOH A H1     1 ? 
HETATM 5454 H H2     . HOH D 4 .   ? 33.522  -14.356 17      1    18.494 ? 1580 HOH A H2     1 ? 
HETATM 5455 O O      . HOH D 4 .   ? -0.301  -29.311 28.619  1    25.461 ? 1581 HOH A O      1 ? 
HETATM 5456 H H1     . HOH D 4 .   ? 0.405   -29.984 28.808  1    24.414 ? 1581 HOH A H1     1 ? 
HETATM 5457 H H2     . HOH D 4 .   ? -1.006  -29.422 29.276  1    22.164 ? 1581 HOH A H2     1 ? 
HETATM 5458 O O      . HOH D 4 .   ? 22.835  -25.066 5.288   1    27.656 ? 1582 HOH A O      1 ? 
HETATM 5459 H H1     . HOH D 4 .   ? 23.409  -24.394 5.708   1    25.372 ? 1582 HOH A H1     1 ? 
HETATM 5460 H H2     . HOH D 4 .   ? 21.902  -24.768 5.322   1    26.052 ? 1582 HOH A H2     1 ? 
HETATM 5461 O O      . HOH D 4 .   ? 23.95   -17.588 22.247  1    14.963 ? 1583 HOH A O      1 ? 
HETATM 5462 H H1     . HOH D 4 .   ? 24.88   -17.353 22.321  1    14.487 ? 1583 HOH A H1     1 ? 
HETATM 5463 H H2     . HOH D 4 .   ? 23.51   -17.327 23.098  1    15.181 ? 1583 HOH A H2     1 ? 
HETATM 5464 O O      . HOH D 4 .   ? 24.115  -7.978  22.13   1    26.204 ? 1584 HOH A O      1 ? 
HETATM 5465 H H1     . HOH D 4 .   ? 24.8    -7.955  22.82   1    26.902 ? 1584 HOH A H1     1 ? 
HETATM 5466 H H2     . HOH D 4 .   ? 23.45   -8.631  22.414  1    28.11  ? 1584 HOH A H2     1 ? 
HETATM 5467 O O      . HOH D 4 .   ? 6.097   -14.317 29.273  1    41.59  ? 1585 HOH A O      1 ? 
HETATM 5468 H H1     . HOH D 4 .   ? 6.62    -14.966 28.771  1    40.431 ? 1585 HOH A H1     1 ? 
HETATM 5469 H H2     . HOH D 4 .   ? 6.214   -13.446 28.853  1    41.698 ? 1585 HOH A H2     1 ? 
HETATM 5470 O O      . HOH D 4 .   ? 6.088   -9.228  13.713  1    29.362 ? 1586 HOH A O      1 ? 
HETATM 5471 H H1     . HOH D 4 .   ? 6.316   -8.927  14.603  1    30.739 ? 1586 HOH A H1     1 ? 
HETATM 5472 H H2     . HOH D 4 .   ? 6.156   -10.188 13.748  1    27.72  ? 1586 HOH A H2     1 ? 
HETATM 5473 O O      . HOH D 4 .   ? 31.076  -25.025 1.272   1    50.657 ? 1587 HOH A O      1 ? 
HETATM 5474 H H1     . HOH D 4 .   ? 30.964  -25.255 2.213   1    49.242 ? 1587 HOH A H1     1 ? 
HETATM 5475 H H2     . HOH D 4 .   ? 30.222  -24.67  0.969   1    48.693 ? 1587 HOH A H2     1 ? 
HETATM 5476 O O      . HOH D 4 .   ? 16.308  -23.852 12.194  1    23.515 ? 1588 HOH A O      1 ? 
HETATM 5477 H H1     . HOH D 4 .   ? 16.89   -23.104 12.403  1    22.616 ? 1588 HOH A H1     1 ? 
HETATM 5478 H H2     . HOH D 4 .   ? 15.932  -23.708 11.293  1    22.991 ? 1588 HOH A H2     1 ? 
HETATM 5479 O O      . HOH D 4 .   ? -10.388 -12.07  16.189  1    40.87  ? 1589 HOH A O      1 ? 
HETATM 5480 H H1     . HOH D 4 .   ? -9.746  -12.444 15.555  1    39.153 ? 1589 HOH A H1     1 ? 
HETATM 5481 H H2     . HOH D 4 .   ? -9.916  -11.88  17.021  1    39.379 ? 1589 HOH A H2     1 ? 
HETATM 5482 O O      . HOH D 4 .   ? 14.691  -37.181 32.04   1    40.196 ? 1590 HOH A O      1 ? 
HETATM 5483 H H1     . HOH D 4 .   ? 14.136  -36.377 32.136  1    40.589 ? 1590 HOH A H1     1 ? 
HETATM 5484 H H2     . HOH D 4 .   ? 14.809  -37.582 32.922  1    38.699 ? 1590 HOH A H2     1 ? 
HETATM 5485 O O      . HOH D 4 .   ? 0.883   0.094   6.871   1    52.299 ? 1591 HOH A O      1 ? 
HETATM 5486 H H1     . HOH D 4 .   ? 1.565   -0.592  6.741   1    47.365 ? 1591 HOH A H1     1 ? 
HETATM 5487 H H2     . HOH D 4 .   ? 1.311   0.976   6.957   1    52.439 ? 1591 HOH A H2     1 ? 
HETATM 5488 O O      . HOH D 4 .   ? -3.45   -27.56  20.505  1    34.76  ? 1592 HOH A O      1 ? 
HETATM 5489 H H1     . HOH D 4 .   ? -2.823  -26.811 20.43   1    31.578 ? 1592 HOH A H1     1 ? 
HETATM 5490 H H2     . HOH D 4 .   ? -3.833  -27.561 21.405  1    34.835 ? 1592 HOH A H2     1 ? 
HETATM 5491 O O      . HOH D 4 .   ? 20.369  -41.324 19.505  1    58.798 ? 1593 HOH A O      1 ? 
HETATM 5492 H H1     . HOH D 4 .   ? 20.355  -40.449 19.926  1    56.212 ? 1593 HOH A H1     1 ? 
HETATM 5493 H H2     . HOH D 4 .   ? 19.528  -41.436 19.022  1    58.241 ? 1593 HOH A H2     1 ? 
HETATM 5494 O O      . HOH D 4 .   ? 18.101  -33.975 33.819  1    24.575 ? 1594 HOH A O      1 ? 
HETATM 5495 H H1     . HOH D 4 .   ? 18.695  -33.459 33.246  1    24.273 ? 1594 HOH A H1     1 ? 
HETATM 5496 H H2     . HOH D 4 .   ? 17.588  -33.338 34.367  1    23.441 ? 1594 HOH A H2     1 ? 
HETATM 5497 O O      . HOH D 4 .   ? 9.186   -7.662  -13.342 1    51.614 ? 1595 HOH A O      1 ? 
HETATM 5498 H H1     . HOH D 4 .   ? 9.111   -8.266  -14.104 1    53.794 ? 1595 HOH A H1     1 ? 
HETATM 5499 H H2     . HOH D 4 .   ? 8.986   -6.753  -13.649 1    51.596 ? 1595 HOH A H2     1 ? 
HETATM 5500 O O      . HOH D 4 .   ? -1.274  -15.575 18.91   1    48.397 ? 1596 HOH A O      1 ? 
HETATM 5501 H H1     . HOH D 4 .   ? -1.005  -15.677 17.966  1    43.879 ? 1596 HOH A H1     1 ? 
HETATM 5502 H H2     . HOH D 4 .   ? -0.963  -14.721 19.286  1    45.72  ? 1596 HOH A H2     1 ? 
HETATM 5503 O O      . HOH D 4 .   ? 15.702  -15.018 28.903  1    14.835 ? 1597 HOH A O      1 ? 
HETATM 5504 H H1     . HOH D 4 .   ? 15.621  -14.119 28.538  1    15.761 ? 1597 HOH A H1     1 ? 
HETATM 5505 H H2     . HOH D 4 .   ? 15.009  -15.48  28.45   1    17.541 ? 1597 HOH A H2     1 ? 
HETATM 5506 O O      . HOH D 4 .   ? 8.444   -6.624  -3.595  1    25.085 ? 1598 HOH A O      1 ? 
HETATM 5507 H H1     . HOH D 4 .   ? 9.097   -6.057  -4.055  1    23.501 ? 1598 HOH A H1     1 ? 
HETATM 5508 H H2     . HOH D 4 .   ? 8.203   -6.176  -2.756  1    24.214 ? 1598 HOH A H2     1 ? 
HETATM 5509 O O      . HOH D 4 .   ? 25.126  -36.052 25.806  1    29.685 ? 1599 HOH A O      1 ? 
HETATM 5510 H H1     . HOH D 4 .   ? 24.887  -36.92  25.419  1    29.841 ? 1599 HOH A H1     1 ? 
HETATM 5511 H H2     . HOH D 4 .   ? 24.331  -35.486 25.826  1    28.384 ? 1599 HOH A H2     1 ? 
HETATM 5512 O O      . HOH D 4 .   ? 38.216  -17.944 1.537   1    40.235 ? 1600 HOH A O      1 ? 
HETATM 5513 H H1     . HOH D 4 .   ? 38.752  -17.309 1.024   1    38.838 ? 1600 HOH A H1     1 ? 
HETATM 5514 H H2     . HOH D 4 .   ? 37.289  -17.645 1.47    1    37.364 ? 1600 HOH A H2     1 ? 
HETATM 5515 O O      . HOH D 4 .   ? 30.626  -10.262 -0.537  1    30.701 ? 1601 HOH A O      1 ? 
HETATM 5516 H H1     . HOH D 4 .   ? 30.656  -9.86   -1.432  1    30.461 ? 1601 HOH A H1     1 ? 
HETATM 5517 H H2     . HOH D 4 .   ? 30.133  -11.097 -0.612  1    28.774 ? 1601 HOH A H2     1 ? 
HETATM 5518 O O      . HOH D 4 .   ? 19.294  -15.337 31.334  1    30.256 ? 1602 HOH A O      1 ? 
HETATM 5519 H H1     . HOH D 4 .   ? 19.894  -15.999 31.71   1    29.197 ? 1602 HOH A H1     1 ? 
HETATM 5520 H H2     . HOH D 4 .   ? 18.489  -15.817 31.073  1    31.609 ? 1602 HOH A H2     1 ? 
HETATM 5521 O O      . HOH D 4 .   ? 10.255  -20.634 -9.376  1    40.08  ? 1603 HOH A O      1 ? 
HETATM 5522 H H1     . HOH D 4 .   ? 10.696  -20.467 -10.236 1    39.839 ? 1603 HOH A H1     1 ? 
HETATM 5523 H H2     . HOH D 4 .   ? 9.377   -21.032 -9.541  1    36.943 ? 1603 HOH A H2     1 ? 
HETATM 5524 O O      . HOH D 4 .   ? 36.41   -11.046 2.326   1    38.662 ? 1604 HOH A O      1 ? 
HETATM 5525 H H1     . HOH D 4 .   ? 36.83   -11.501 1.573   1    37.771 ? 1604 HOH A H1     1 ? 
HETATM 5526 H H2     . HOH D 4 .   ? 36.949  -11.227 3.12    1    39.405 ? 1604 HOH A H2     1 ? 
HETATM 5527 O O      . HOH D 4 .   ? 28.683  -20.78  -3.227  1    19.182 ? 1605 HOH A O      1 ? 
HETATM 5528 H H1     . HOH D 4 .   ? 29.535  -20.622 -3.672  1    18.935 ? 1605 HOH A H1     1 ? 
HETATM 5529 H H2     . HOH D 4 .   ? 28.256  -19.912 -3.168  1    18.91  ? 1605 HOH A H2     1 ? 
HETATM 5530 O O      . HOH D 4 .   ? 38.661  -32.192 21.795  1    18.994 ? 1606 HOH A O      1 ? 
HETATM 5531 H H1     . HOH D 4 .   ? 38.359  -31.358 21.391  1    19.828 ? 1606 HOH A H1     1 ? 
HETATM 5532 H H2     . HOH D 4 .   ? 37.853  -32.707 21.907  1    19.815 ? 1606 HOH A H2     1 ? 
HETATM 5533 O O      . HOH D 4 .   ? 14.962  -31.772 17.607  1    20.626 ? 1607 HOH A O      1 ? 
HETATM 5534 H H1     . HOH D 4 .   ? 15.245  -30.995 17.082  1    19.308 ? 1607 HOH A H1     1 ? 
HETATM 5535 H H2     . HOH D 4 .   ? 14.593  -31.433 18.441  1    19.73  ? 1607 HOH A H2     1 ? 
HETATM 5536 O O      . HOH D 4 .   ? 13.724  -0.136  7.57    1    29.53  ? 1608 HOH A O      1 ? 
HETATM 5537 H H1     . HOH D 4 .   ? 14.181  -0.496  6.788   1    29.028 ? 1608 HOH A H1     1 ? 
HETATM 5538 H H2     . HOH D 4 .   ? 12.973  -0.728  7.771   1    28.595 ? 1608 HOH A H2     1 ? 
HETATM 5539 O O      . HOH D 4 .   ? 36.966  -18.486 23.221  1    24.097 ? 1609 HOH A O      1 ? 
HETATM 5540 H H1     . HOH D 4 .   ? 37.706  -18.098 23.711  1    22.803 ? 1609 HOH A H1     1 ? 
HETATM 5541 H H2     . HOH D 4 .   ? 36.863  -17.933 22.42   1    22.209 ? 1609 HOH A H2     1 ? 
HETATM 5542 O O      . HOH D 4 .   ? 7.815   -27.065 33.7    1    12.495 ? 1610 HOH A O      1 ? 
HETATM 5543 H H1     . HOH D 4 .   ? 8.517   -27.452 33.173  1    13.677 ? 1610 HOH A H1     1 ? 
HETATM 5544 H H2     . HOH D 4 .   ? 7.549   -26.276 33.258  1    12.055 ? 1610 HOH A H2     1 ? 
HETATM 5545 O O      . HOH D 4 .   ? 34.925  -23.921 10.691  1    43.361 ? 1611 HOH A O      1 ? 
HETATM 5546 H H1     . HOH D 4 .   ? 35.362  -23.045 10.789  1    37.659 ? 1611 HOH A H1     1 ? 
HETATM 5547 H H2     . HOH D 4 .   ? 33.983  -23.844 10.96   1    39.091 ? 1611 HOH A H2     1 ? 
HETATM 5548 O O      . HOH D 4 .   ? 28.007  -25.991 10.036  1    16.399 ? 1612 HOH A O      1 ? 
HETATM 5549 H H1     . HOH D 4 .   ? 28.323  -25.11  9.746   1    18.046 ? 1612 HOH A H1     1 ? 
HETATM 5550 H H2     . HOH D 4 .   ? 27.561  -25.839 10.877  1    16.052 ? 1612 HOH A H2     1 ? 
HETATM 5551 O O      . HOH D 4 .   ? 32.128  -13.662 -0.232  1    17.852 ? 1613 HOH A O      1 ? 
HETATM 5552 H H1     . HOH D 4 .   ? 32.568  -14.462 0.097   1    17.687 ? 1613 HOH A H1     1 ? 
HETATM 5553 H H2     . HOH D 4 .   ? 32.096  -13.051 0.526   1    17.867 ? 1613 HOH A H2     1 ? 
HETATM 5554 O O      . HOH D 4 .   ? 17.726  0.925   1.562   1    47.369 ? 1614 HOH A O      1 ? 
HETATM 5555 H H1     . HOH D 4 .   ? 17.361  0.037   1.74    1    45.869 ? 1614 HOH A H1     1 ? 
HETATM 5556 H H2     . HOH D 4 .   ? 17.221  1.297   0.815   1    44.877 ? 1614 HOH A H2     1 ? 
HETATM 5557 O O      . HOH D 4 .   ? 9.327   -19.544 -7.604  1    33.989 ? 1615 HOH A O      1 ? 
HETATM 5558 H H1     . HOH D 4 .   ? 10.125  -20.078 -7.774  1    32.245 ? 1615 HOH A H1     1 ? 
HETATM 5559 H H2     . HOH D 4 .   ? 9.577   -18.819 -7.005  1    33.833 ? 1615 HOH A H2     1 ? 
HETATM 5560 O O      . HOH D 4 .   ? 25.676  -25.532 0.958   1    32.341 ? 1616 HOH A O      1 ? 
HETATM 5561 H H1     . HOH D 4 .   ? 26.524  -26.029 0.922   1    30.972 ? 1616 HOH A H1     1 ? 
HETATM 5562 H H2     . HOH D 4 .   ? 25.62   -24.916 0.198   1    32.93  ? 1616 HOH A H2     1 ? 
HETATM 5563 O O      . HOH D 4 .   ? 38.159  -24.417 4.893   1    48.125 ? 1617 HOH A O      1 ? 
HETATM 5564 H H1     . HOH D 4 .   ? 38.274  -23.988 5.766   1    46.76  ? 1617 HOH A H1     1 ? 
HETATM 5565 H H2     . HOH D 4 .   ? 37.446  -23.947 4.425   1    42.889 ? 1617 HOH A H2     1 ? 
HETATM 5566 O O      . HOH D 4 .   ? 34.897  -11.737 12.197  1    23.729 ? 1618 HOH A O      1 ? 
HETATM 5567 H H1     . HOH D 4 .   ? 35.316  -10.866 12.2    1    21.298 ? 1618 HOH A H1     1 ? 
HETATM 5568 H H2     . HOH D 4 .   ? 34.006  -11.64  12.561  1    23.464 ? 1618 HOH A H2     1 ? 
HETATM 5569 O O      . HOH D 4 .   ? 31.22   -19.211 6.217   1    19.233 ? 1619 HOH A O      1 ? 
HETATM 5570 H H1     . HOH D 4 .   ? 31.959  -19.055 5.608   1    22.321 ? 1619 HOH A H1     1 ? 
HETATM 5571 H H2     . HOH D 4 .   ? 30.933  -20.106 6.002   1    19.688 ? 1619 HOH A H2     1 ? 
HETATM 5572 O O      . HOH D 4 .   ? -2.979  -31.019 25.403  1    30.737 ? 1620 HOH A O      1 ? 
HETATM 5573 H H1     . HOH D 4 .   ? -3.232  -30.118 25.646  1    29.462 ? 1620 HOH A H1     1 ? 
HETATM 5574 H H2     . HOH D 4 .   ? -3.615  -31.329 24.737  1    30.981 ? 1620 HOH A H2     1 ? 
HETATM 5575 O O      . HOH D 4 .   ? 23.935  -33.696 21.473  1    21.331 ? 1621 HOH A O      1 ? 
HETATM 5576 H H1     . HOH D 4 .   ? 23.605  -32.781 21.457  1    23.172 ? 1621 HOH A H1     1 ? 
HETATM 5577 H H2     . HOH D 4 .   ? 23.203  -34.261 21.153  1    23.166 ? 1621 HOH A H2     1 ? 
HETATM 5578 O O      . HOH D 4 .   ? 16.196  -43.633 24.08   1    29.799 ? 1622 HOH A O      1 ? 
HETATM 5579 H H1     . HOH D 4 .   ? 15.816  -42.771 23.85   1    29.005 ? 1622 HOH A H1     1 ? 
HETATM 5580 H H2     . HOH D 4 .   ? 16.13   -43.761 25.048  1    30.842 ? 1622 HOH A H2     1 ? 
HETATM 5581 O O      . HOH D 4 .   ? 34.653  -9.788  10.188  1    26.835 ? 1623 HOH A O      1 ? 
HETATM 5582 H H1     . HOH D 4 .   ? 34.432  -10.735 10.283  1    26.85  ? 1623 HOH A H1     1 ? 
HETATM 5583 H H2     . HOH D 4 .   ? 34.532  -9.354  11.051  1    26.225 ? 1623 HOH A H2     1 ? 
HETATM 5584 O O      . HOH D 4 .   ? 39.186  -14.249 28.6    1    32.882 ? 1624 HOH A O      1 ? 
HETATM 5585 H H1     . HOH D 4 .   ? 39.93   -13.618 28.56   1    32.394 ? 1624 HOH A H1     1 ? 
HETATM 5586 H H2     . HOH D 4 .   ? 38.746  -14.118 29.461  1    31.605 ? 1624 HOH A H2     1 ? 
HETATM 5587 O O      . HOH D 4 .   ? 2.965   -34.642 31.408  1    33.916 ? 1625 HOH A O      1 ? 
HETATM 5588 H H1     . HOH D 4 .   ? 3.017   -34.229 32.285  1    31.664 ? 1625 HOH A H1     1 ? 
HETATM 5589 H H2     . HOH D 4 .   ? 2.679   -35.57  31.535  1    32.121 ? 1625 HOH A H2     1 ? 
HETATM 5590 O O      . HOH D 4 .   ? 8.436   -30.073 28.901  1    21.301 ? 1626 HOH A O      1 ? 
HETATM 5591 H H1     . HOH D 4 .   ? 7.953   -30.309 28.091  1    21.148 ? 1626 HOH A H1     1 ? 
HETATM 5592 H H2     . HOH D 4 .   ? 7.995   -30.541 29.624  1    23.077 ? 1626 HOH A H2     1 ? 
HETATM 5593 O O      . HOH D 4 .   ? 34.292  -26.744 14.775  1    44.727 ? 1627 HOH A O      1 ? 
HETATM 5594 H H1     . HOH D 4 .   ? 34.093  -25.965 15.331  1    43.328 ? 1627 HOH A H1     1 ? 
HETATM 5595 H H2     . HOH D 4 .   ? 33.769  -26.663 13.962  1    37.796 ? 1627 HOH A H2     1 ? 
HETATM 5596 O O      . HOH D 4 .   ? 33.192  -31.594 19.9    1    27.607 ? 1628 HOH A O      1 ? 
HETATM 5597 H H1     . HOH D 4 .   ? 33.801  -30.935 20.291  1    27.975 ? 1628 HOH A H1     1 ? 
HETATM 5598 H H2     . HOH D 4 .   ? 32.315  -31.465 20.288  1    25.146 ? 1628 HOH A H2     1 ? 
HETATM 5599 O O      . HOH D 4 .   ? 27.426  -0.217  9.57    1    22.382 ? 1629 HOH A O      1 ? 
HETATM 5600 H H1     . HOH D 4 .   ? 28.185  0.012   10.125  1    24.685 ? 1629 HOH A H1     1 ? 
HETATM 5601 H H2     . HOH D 4 .   ? 27.8    -0.383  8.708   1    21.309 ? 1629 HOH A H2     1 ? 
HETATM 5602 O O      . HOH D 4 .   ? -13.954 -19.129 25.204  1    52.217 ? 1630 HOH A O      1 ? 
HETATM 5603 H H1     . HOH D 4 .   ? -13.673 -18.256 25.530  1    49.972 ? 1630 HOH A H1     1 ? 
HETATM 5604 H H2     . HOH D 4 .   ? -13.502 -19.807 25.737  1    51.949 ? 1630 HOH A H2     1 ? 
HETATM 5605 O O      . HOH D 4 .   ? 21.792  -19.775 25.498  1    16.374 ? 1631 HOH A O      1 ? 
HETATM 5606 H H1     . HOH D 4 .   ? 20.84   -19.679 25.466  1    18.048 ? 1631 HOH A H1     1 ? 
HETATM 5607 H H2     . HOH D 4 .   ? 21.956  -20.286 26.304  1    16.616 ? 1631 HOH A H2     1 ? 
HETATM 5608 O O      . HOH D 4 .   ? 24.454  -36.483 28.287  1    63.495 ? 1632 HOH A O      1 ? 
HETATM 5609 H H1     . HOH D 4 .   ? 25.428  -36.451 28.229  1    59.616 ? 1632 HOH A H1     1 ? 
HETATM 5610 H H2     . HOH D 4 .   ? 24.107  -36.881 27.463  1    62.082 ? 1632 HOH A H2     1 ? 
HETATM 5611 O O      . HOH D 4 .   ? 8.049   -9.281  6.13    1    23.901 ? 1633 HOH A O      1 ? 
HETATM 5612 H H1     . HOH D 4 .   ? 7.715   -8.559  6.664   1    25.254 ? 1633 HOH A H1     1 ? 
HETATM 5613 H H2     . HOH D 4 .   ? 7.289   -9.865  5.99    1    24.797 ? 1633 HOH A H2     1 ? 
HETATM 5614 O O      . HOH D 4 .   ? 8.27    -14.574 33.365  1    40.061 ? 1634 HOH A O      1 ? 
HETATM 5615 H H1     . HOH D 4 .   ? 8.051   -15.291 32.742  1    37.839 ? 1634 HOH A H1     1 ? 
HETATM 5616 H H2     . HOH D 4 .   ? 8.785   -13.913 32.87   1    40.764 ? 1634 HOH A H2     1 ? 
HETATM 5617 O O      . HOH D 4 .   ? 30.395  -26.439 7.304   1    21.186 ? 1635 HOH A O      1 ? 
HETATM 5618 H H1     . HOH D 4 .   ? 31.11   -26.194 7.916   1    21.075 ? 1635 HOH A H1     1 ? 
HETATM 5619 H H2     . HOH D 4 .   ? 30.815  -26.541 6.439   1    21.999 ? 1635 HOH A H2     1 ? 
HETATM 5620 O O      . HOH D 4 .   ? 22.845  -0.637  19.08   1    35.725 ? 1636 HOH A O      1 ? 
HETATM 5621 H H1     . HOH D 4 .   ? 22.698  -1.47   19.593  1    29.383 ? 1636 HOH A H1     1 ? 
HETATM 5622 H H2     . HOH D 4 .   ? 23.79   -0.573  18.77   1    33.661 ? 1636 HOH A H2     1 ? 
HETATM 5623 O O      . HOH D 4 .   ? -12.302 -23.628 16.699  1    49.292 ? 1637 HOH A O      1 ? 
HETATM 5624 H H1     . HOH D 4 .   ? -12.259 -24.585 16.508  1    50.721 ? 1637 HOH A H1     1 ? 
HETATM 5625 H H2     . HOH D 4 .   ? -11.531 -23.201 16.289  1    47.918 ? 1637 HOH A H2     1 ? 
HETATM 5626 O O      . HOH D 4 .   ? 23.37   -29.093 5.53    1    30.363 ? 1638 HOH A O      1 ? 
HETATM 5627 H H1     . HOH D 4 .   ? 23.417  -28.145 5.281   1    30.12  ? 1638 HOH A H1     1 ? 
HETATM 5628 H H2     . HOH D 4 .   ? 22.826  -29.16  6.336   1    28.927 ? 1638 HOH A H2     1 ? 
HETATM 5629 O O      . HOH D 4 .   ? -5.941  -27.357 24.764  1    42.828 ? 1639 HOH A O      1 ? 
HETATM 5630 H H1     . HOH D 4 .   ? -5.308  -27.254 25.499  1    42.293 ? 1639 HOH A H1     1 ? 
HETATM 5631 H H2     . HOH D 4 .   ? -5.763  -28.216 24.342  1    41.612 ? 1639 HOH A H2     1 ? 
HETATM 5632 O O      . HOH D 4 .   ? 21.767  -21.507 16.448  1    25.772 ? 1640 HOH A O      1 ? 
HETATM 5633 H H1     . HOH D 4 .   ? 21.907  -21.071 17.309  1    28.671 ? 1640 HOH A H1     1 ? 
HETATM 5634 H H2     . HOH D 4 .   ? 20.862  -21.319 16.193  1    25.708 ? 1640 HOH A H2     1 ? 
HETATM 5635 O O      . HOH D 4 .   ? 2.036   3.519   -6.183  1    44.483 ? 1641 HOH A O      1 ? 
HETATM 5636 H H1     . HOH D 4 .   ? 2.175   4.368   -5.727  1    39.966 ? 1641 HOH A H1     1 ? 
HETATM 5637 H H2     . HOH D 4 .   ? 1.112   3.482   -6.518  1    42.07  ? 1641 HOH A H2     1 ? 
HETATM 5638 O O      . HOH D 4 .   ? 25.79   -6.358  21.156  1    33.285 ? 1642 HOH A O      1 ? 
HETATM 5639 H H1     . HOH D 4 .   ? 26.47   -6.919  20.733  1    31.353 ? 1642 HOH A H1     1 ? 
HETATM 5640 H H2     . HOH D 4 .   ? 25.231  -6.926  21.719  1    31.092 ? 1642 HOH A H2     1 ? 
HETATM 5641 O O      . HOH D 4 .   ? 29.707  -8.125  19.457  1    36.599 ? 1643 HOH A O      1 ? 
HETATM 5642 H H1     . HOH D 4 .   ? 29.2    -8.153  20.289  1    35.917 ? 1643 HOH A H1     1 ? 
HETATM 5643 H H2     . HOH D 4 .   ? 29.201  -7.569  18.842  1    36.484 ? 1643 HOH A H2     1 ? 
HETATM 5644 O O      . HOH D 4 .   ? 26.172  -24.904 11.808  1    20.717 ? 1644 HOH A O      1 ? 
HETATM 5645 H H1     . HOH D 4 .   ? 26.745  -24.174 12.162  1    19.63  ? 1644 HOH A H1     1 ? 
HETATM 5646 H H2     . HOH D 4 .   ? 25.288  -24.862 12.225  1    20.206 ? 1644 HOH A H2     1 ? 
HETATM 5647 O O      . HOH D 4 .   ? 33.086  -17.893 28.626  1    25.91  ? 1645 HOH A O      1 ? 
HETATM 5648 H H1     . HOH D 4 .   ? 33.606  -17.548 27.871  1    24.044 ? 1645 HOH A H1     1 ? 
HETATM 5649 H H2     . HOH D 4 .   ? 32.469  -18.588 28.308  1    25.153 ? 1645 HOH A H2     1 ? 
HETATM 5650 O O      . HOH D 4 .   ? 5.362   -26.562 10.166  1    40.219 ? 1646 HOH A O      1 ? 
HETATM 5651 H H1     . HOH D 4 .   ? 5.656   -27.197 9.479   1    38.237 ? 1646 HOH A H1     1 ? 
HETATM 5652 H H2     . HOH D 4 .   ? 5.017   -25.757 9.725   1    39.135 ? 1646 HOH A H2     1 ? 
HETATM 5653 O O      . HOH D 4 .   ? 7.977   -31.632 16.002  1    33.385 ? 1647 HOH A O      1 ? 
HETATM 5654 H H1     . HOH D 4 .   ? 7.408   -32.305 15.574  1    30.81  ? 1647 HOH A H1     1 ? 
HETATM 5655 H H2     . HOH D 4 .   ? 7.667   -31.499 16.921  1    31.982 ? 1647 HOH A H2     1 ? 
HETATM 5656 O O      . HOH D 4 .   ? 3.46    -18.128 33.982  1    33.554 ? 1648 HOH A O      1 ? 
HETATM 5657 H H1     . HOH D 4 .   ? 4.172   -18.783 33.914  1    33.113 ? 1648 HOH A H1     1 ? 
HETATM 5658 H H2     . HOH D 4 .   ? 3.893   -17.273 33.875  1    33.054 ? 1648 HOH A H2     1 ? 
HETATM 5659 O O      . HOH D 4 .   ? 25.499  -20.664 27.682  1    19.363 ? 1649 HOH A O      1 ? 
HETATM 5660 H H1     . HOH D 4 .   ? 26      -20.958 26.918  1    21.632 ? 1649 HOH A H1     1 ? 
HETATM 5661 H H2     . HOH D 4 .   ? 25.919  -21.158 28.384  1    19.12  ? 1649 HOH A H2     1 ? 
HETATM 5662 O O      . HOH D 4 .   ? 1.241   -12.593 26.902  1    42.665 ? 1650 HOH A O      1 ? 
HETATM 5663 H H1     . HOH D 4 .   ? 2.197   -12.443 27.032  1    40.764 ? 1650 HOH A H1     1 ? 
HETATM 5664 H H2     . HOH D 4 .   ? 1.007   -13.438 27.33   1    41.32  ? 1650 HOH A H2     1 ? 
HETATM 5665 O O      . HOH D 4 .   ? 7.136   -24.395 32.691  1    16.42  ? 1651 HOH A O      1 ? 
HETATM 5666 H H1     . HOH D 4 .   ? 7.57    -24.042 31.874  1    16.763 ? 1651 HOH A H1     1 ? 
HETATM 5667 H H2     . HOH D 4 .   ? 7.44    -23.825 33.42   1    16.209 ? 1651 HOH A H2     1 ? 
HETATM 5668 O O      . HOH D 4 .   ? 24.688  -37.108 19.702  1    36.069 ? 1652 HOH A O      1 ? 
HETATM 5669 H H1     . HOH D 4 .   ? 24.902  -36.327 19.161  1    34.903 ? 1652 HOH A H1     1 ? 
HETATM 5670 H H2     . HOH D 4 .   ? 24.031  -37.628 19.208  1    32.748 ? 1652 HOH A H2     1 ? 
HETATM 5671 O O      . HOH D 4 .   ? 2.797   -21.458 9.557   1    32.25  ? 1653 HOH A O      1 ? 
HETATM 5672 H H1     . HOH D 4 .   ? 3.457   -21.913 9.006   1    32.302 ? 1653 HOH A H1     1 ? 
HETATM 5673 H H2     . HOH D 4 .   ? 3.07    -20.524 9.642   1    31.85  ? 1653 HOH A H2     1 ? 
HETATM 5674 O O      . HOH D 4 .   ? 11.212  -5.018  20.352  1    30.854 ? 1654 HOH A O      1 ? 
HETATM 5675 H H1     . HOH D 4 .   ? 10.466  -5.621  20.443  1    30.272 ? 1654 HOH A H1     1 ? 
HETATM 5676 H H2     . HOH D 4 .   ? 11.739  -5.42   19.652  1    31.327 ? 1654 HOH A H2     1 ? 
HETATM 5677 O O      . HOH D 4 .   ? 25.306  -25.750 36.659  1    53.409 ? 1655 HOH A O      1 ? 
HETATM 5678 H H1     . HOH D 4 .   ? 25.322  -26.132 37.566  1    46.664 ? 1655 HOH A H1     1 ? 
HETATM 5679 H H2     . HOH D 4 .   ? 26.113  -25.205 36.488  1    51.068 ? 1655 HOH A H2     1 ? 
HETATM 5680 O O      . HOH D 4 .   ? 1.421   -13.672 17.315  1    35.96  ? 1656 HOH A O      1 ? 
HETATM 5681 H H1     . HOH D 4 .   ? 2.323   -13.386 17.49   1    39.378 ? 1656 HOH A H1     1 ? 
HETATM 5682 H H2     . HOH D 4 .   ? 0.862   -12.924 17.564  1    37.796 ? 1656 HOH A H2     1 ? 
HETATM 5683 O O      . HOH D 4 .   ? 31.535  -24.64  30.938  1    22.424 ? 1657 HOH A O      1 ? 
HETATM 5684 H H1     . HOH D 4 .   ? 30.886  -24.633 30.238  1    24.945 ? 1657 HOH A H1     1 ? 
HETATM 5685 H H2     . HOH D 4 .   ? 32.056  -25.418 30.736  1    25.58  ? 1657 HOH A H2     1 ? 
HETATM 5686 O O      . HOH D 4 .   ? 41.781  -15.814 20.465  1    30.838 ? 1658 HOH A O      1 ? 
HETATM 5687 H H1     . HOH D 4 .   ? 42.240  -16.535 20.945  1    31.315 ? 1658 HOH A H1     1 ? 
HETATM 5688 H H2     . HOH D 4 .   ? 41.457  -15.168 21.132  1    31.925 ? 1658 HOH A H2     1 ? 
HETATM 5689 O O      . HOH D 4 .   ? 38.974  -19.088 10.343  1    21.054 ? 1659 HOH A O      1 ? 
HETATM 5690 H H1     . HOH D 4 .   ? 39.872  -18.762 10.198  1    19.789 ? 1659 HOH A H1     1 ? 
HETATM 5691 H H2     . HOH D 4 .   ? 38.677  -19.503 9.512   1    18.991 ? 1659 HOH A H2     1 ? 
HETATM 5692 O O      . HOH D 4 .   ? 12.767  0.854   15.078  1    37.246 ? 1660 HOH A O      1 ? 
HETATM 5693 H H1     . HOH D 4 .   ? 12.033  1.017   14.456  1    37.133 ? 1660 HOH A H1     1 ? 
HETATM 5694 H H2     . HOH D 4 .   ? 13.228  1.7     15.213  1    36.753 ? 1660 HOH A H2     1 ? 
HETATM 5695 O O      . HOH D 4 .   ? 6.836   -33.615 16.157  1    35.205 ? 1661 HOH A O      1 ? 
HETATM 5696 H H1     . HOH D 4 .   ? 6.65    -33.44  17.1    1    35.56  ? 1661 HOH A H1     1 ? 
HETATM 5697 H H2     . HOH D 4 .   ? 5.991   -33.853 15.734  1    34.809 ? 1661 HOH A H2     1 ? 
HETATM 5698 O O      . HOH D 4 .   ? 37.184  -4.649  5.924   1    31.01  ? 1662 HOH A O      1 ? 
HETATM 5699 H H1     . HOH D 4 .   ? 37.517  -3.814  6.308   1    28.671 ? 1662 HOH A H1     1 ? 
HETATM 5700 H H2     . HOH D 4 .   ? 36.631  -4.409  5.147   1    28.86  ? 1662 HOH A H2     1 ? 
HETATM 5701 O O      . HOH D 4 .   ? 19.614  -39.631 13.899  1    43.574 ? 1663 HOH A O      1 ? 
HETATM 5702 H H1     . HOH D 4 .   ? 20.527  -39.669 14.27   1    38.857 ? 1663 HOH A H1     1 ? 
HETATM 5703 H H2     . HOH D 4 .   ? 19.038  -39.044 14.453  1    41.799 ? 1663 HOH A H2     1 ? 
HETATM 5704 O O      . HOH D 4 .   ? 16.974  -4.967  21.025  1    23.752 ? 1664 HOH A O      1 ? 
HETATM 5705 H H1     . HOH D 4 .   ? 16.827  -4.446  21.829  1    22.885 ? 1664 HOH A H1     1 ? 
HETATM 5706 H H2     . HOH D 4 .   ? 16.102  -5.274  20.686  1    20.538 ? 1664 HOH A H2     1 ? 
HETATM 5707 O O      . HOH D 4 .   ? 38.878  -10.176 19.905  1    57.797 ? 1665 HOH A O      1 ? 
HETATM 5708 H H1     . HOH D 4 .   ? 39.055  -10.774 19.156  1    55.688 ? 1665 HOH A H1     1 ? 
HETATM 5709 H H2     . HOH D 4 .   ? 39.164  -9.283  19.644  1    58.403 ? 1665 HOH A H2     1 ? 
HETATM 5710 O O      . HOH D 4 .   ? 19.461  -40.677 24.774  1    28.309 ? 1666 HOH A O      1 ? 
HETATM 5711 H H1     . HOH D 4 .   ? 20.309  -40.668 25.258  1    28.333 ? 1666 HOH A H1     1 ? 
HETATM 5712 H H2     . HOH D 4 .   ? 18.756  -40.74  25.445  1    28.128 ? 1666 HOH A H2     1 ? 
HETATM 5713 O O      . HOH D 4 .   ? 2.106   -26.886 16.187  1    21.413 ? 1667 HOH A O      1 ? 
HETATM 5714 H H1     . HOH D 4 .   ? 2.688   -27.651 16.35   1    21.225 ? 1667 HOH A H1     1 ? 
HETATM 5715 H H2     . HOH D 4 .   ? 1.633   -26.726 17.031  1    21.605 ? 1667 HOH A H2     1 ? 
HETATM 5716 O O      . HOH D 4 .   ? 16.818  -39.439 28.805  1    37.86  ? 1668 HOH A O      1 ? 
HETATM 5717 H H1     . HOH D 4 .   ? 17.386  -39.257 29.57   1    35.843 ? 1668 HOH A H1     1 ? 
HETATM 5718 H H2     . HOH D 4 .   ? 16.012  -38.902 28.919  1    38.488 ? 1668 HOH A H2     1 ? 
HETATM 5719 O O      . HOH D 4 .   ? 6.445   -28.401 15.627  1    25.603 ? 1669 HOH A O      1 ? 
HETATM 5720 H H1     . HOH D 4 .   ? 7.114   -28.803 15.036  1    26.133 ? 1669 HOH A H1     1 ? 
HETATM 5721 H H2     . HOH D 4 .   ? 6.729   -27.482 15.782  1    25.169 ? 1669 HOH A H2     1 ? 
HETATM 5722 O O      . HOH D 4 .   ? 20.183  -14.657 27.512  1    27.91  ? 1670 HOH A O      1 ? 
HETATM 5723 H H1     . HOH D 4 .   ? 20.445  -13.744 27.419  1    29.071 ? 1670 HOH A H1     1 ? 
HETATM 5724 H H2     . HOH D 4 .   ? 20.06   -14.93  26.596  1    28.52  ? 1670 HOH A H2     1 ? 
HETATM 5725 O O      . HOH D 4 .   ? -9.003  -17.309 14.729  1    53.849 ? 1671 HOH A O      1 ? 
HETATM 5726 H H1     . HOH D 4 .   ? -8.98   -17.052 13.781  1    52.648 ? 1671 HOH A H1     1 ? 
HETATM 5727 H H2     . HOH D 4 .   ? -9.229  -16.522 15.269  1    47.399 ? 1671 HOH A H2     1 ? 
HETATM 5728 O O      . HOH D 4 .   ? 13.991  -36.145 14.891  1    28.64  ? 1672 HOH A O      1 ? 
HETATM 5729 H H1     . HOH D 4 .   ? 14.685  -36.132 14.212  1    30.288 ? 1672 HOH A H1     1 ? 
HETATM 5730 H H2     . HOH D 4 .   ? 13.531  -35.295 14.807  1    27.932 ? 1672 HOH A H2     1 ? 
HETATM 5731 O O      . HOH D 4 .   ? 31.875  -19.344 -0.88   1    26.255 ? 1673 HOH A O      1 ? 
HETATM 5732 H H1     . HOH D 4 .   ? 32.639  -19.111 -0.314  1    24.915 ? 1673 HOH A H1     1 ? 
HETATM 5733 H H2     . HOH D 4 .   ? 31.14   -18.723 -0.667  1    25.832 ? 1673 HOH A H2     1 ? 
HETATM 5734 O O      . HOH D 4 .   ? -3.571  -19.131 17.408  1    42.075 ? 1674 HOH A O      1 ? 
HETATM 5735 H H1     . HOH D 4 .   ? -2.794  -19.647 17.105  1    41.112 ? 1674 HOH A H1     1 ? 
HETATM 5736 H H2     . HOH D 4 .   ? -3.364  -18.766 18.288  1    39.886 ? 1674 HOH A H2     1 ? 
HETATM 5737 O O      . HOH D 4 .   ? 5.796   1.376   22.539  1    48.475 ? 1675 HOH A O      1 ? 
HETATM 5738 H H1     . HOH D 4 .   ? 5.538   1.943   21.786  1    52.84  ? 1675 HOH A H1     1 ? 
HETATM 5739 H H2     . HOH D 4 .   ? 5.595   0.452   22.294  1    51.155 ? 1675 HOH A H2     1 ? 
HETATM 5740 O O      . HOH D 4 .   ? 34.905  -15.728 -0.378  1    45.755 ? 1676 HOH A O      1 ? 
HETATM 5741 H H1     . HOH D 4 .   ? 35.62   -15.355 -0.933  1    47.233 ? 1676 HOH A H1     1 ? 
HETATM 5742 H H2     . HOH D 4 .   ? 34.674  -16.605 -0.73   1    40.281 ? 1676 HOH A H2     1 ? 
HETATM 5743 O O      . HOH D 4 .   ? 9.992   -22.767 39.092  1    18.691 ? 1677 HOH A O      1 ? 
HETATM 5744 H H1     . HOH D 4 .   ? 10.729  -22.189 38.872  1    19.707 ? 1677 HOH A H1     1 ? 
HETATM 5745 H H2     . HOH D 4 .   ? 9.932   -23.359 38.348  1    20.079 ? 1677 HOH A H2     1 ? 
HETATM 5746 O O      . HOH D 4 .   ? 34.636  -14.933 13.225  1    22.72  ? 1678 HOH A O      1 ? 
HETATM 5747 H H1     . HOH D 4 .   ? 33.84   -14.336 13.337  1    21.724 ? 1678 HOH A H1     1 ? 
HETATM 5748 H H2     . HOH D 4 .   ? 34.421  -15.864 13.539  1    21.511 ? 1678 HOH A H2     1 ? 
HETATM 5749 O O      . HOH D 4 .   ? 0.197   -24.703 27.482  1    29.557 ? 1679 HOH A O      1 ? 
HETATM 5750 H H1     . HOH D 4 .   ? 0.439   -25.354 28.163  1    29.291 ? 1679 HOH A H1     1 ? 
HETATM 5751 H H2     . HOH D 4 .   ? 0.759   -24.89  26.714  1    26.396 ? 1679 HOH A H2     1 ? 
HETATM 5752 O O      . HOH D 4 .   ? 20.566  -26.377 3.09    1    22.893 ? 1680 HOH A O      1 ? 
HETATM 5753 H H1     . HOH D 4 .   ? 20.276  -26.167 3.99    1    21.899 ? 1680 HOH A H1     1 ? 
HETATM 5754 H H2     . HOH D 4 .   ? 19.769  -26.62  2.6     1    24.268 ? 1680 HOH A H2     1 ? 
HETATM 5755 O O      . HOH D 4 .   ? 23.5    -12.28  16.951  1    18.224 ? 1681 HOH A O      1 ? 
HETATM 5756 H H1     . HOH D 4 .   ? 23.273  -12.019 17.857  1    17.112 ? 1681 HOH A H1     1 ? 
HETATM 5757 H H2     . HOH D 4 .   ? 23.447  -13.272 16.916  1    17.629 ? 1681 HOH A H2     1 ? 
HETATM 5758 O O      . HOH D 4 .   ? 19.341  -23.342 -14.506 1    23.51  ? 1682 HOH A O      1 ? 
HETATM 5759 H H1     . HOH D 4 .   ? 19.693  -24.144 -14.086 1    22.78  ? 1682 HOH A H1     1 ? 
HETATM 5760 H H2     . HOH D 4 .   ? 19.036  -22.748 -13.795 1    21.563 ? 1682 HOH A H2     1 ? 
HETATM 5761 O O      . HOH D 4 .   ? 32.587  0.098   17.054  1    65.388 ? 1683 HOH A O      1 ? 
HETATM 5762 H H1     . HOH D 4 .   ? 33.417  -0.36   16.801  1    56.885 ? 1683 HOH A H1     1 ? 
HETATM 5763 H H2     . HOH D 4 .   ? 32.232  0.586   16.277  1    63.452 ? 1683 HOH A H2     1 ? 
HETATM 5764 O O      . HOH D 4 .   ? 28.157  -27.927 20.428  1    13.953 ? 1684 HOH A O      1 ? 
HETATM 5765 H H1     . HOH D 4 .   ? 28.852  -28.37  19.937  1    14.647 ? 1684 HOH A H1     1 ? 
HETATM 5766 H H2     . HOH D 4 .   ? 27.478  -27.873 19.771  1    15.273 ? 1684 HOH A H2     1 ? 
HETATM 5767 O O      . HOH D 4 .   ? 22.587  -40.214 23.08   1    33.552 ? 1685 HOH A O      1 ? 
HETATM 5768 H H1     . HOH D 4 .   ? 21.907  -39.744 23.597  1    31.224 ? 1685 HOH A H1     1 ? 
HETATM 5769 H H2     . HOH D 4 .   ? 22.22   -40.414 22.188  1    32.35  ? 1685 HOH A H2     1 ? 
HETATM 5770 O O      . HOH D 4 .   ? 18.369  -27.701 -9.829  1    17.81  ? 1686 HOH A O      1 ? 
HETATM 5771 H H1     . HOH D 4 .   ? 18.953  -26.994 -9.532  1    18.497 ? 1686 HOH A H1     1 ? 
HETATM 5772 H H2     . HOH D 4 .   ? 17.532  -27.579 -9.365  1    18.944 ? 1686 HOH A H2     1 ? 
HETATM 5773 O O      . HOH D 4 .   ? 28.722  -30.576 25.519  1    19.119 ? 1687 HOH A O      1 ? 
HETATM 5774 H H1     . HOH D 4 .   ? 28.599  -29.619 25.562  1    22.879 ? 1687 HOH A H1     1 ? 
HETATM 5775 H H2     . HOH D 4 .   ? 28.043  -30.897 26.121  1    21.228 ? 1687 HOH A H2     1 ? 
HETATM 5776 O O      . HOH D 4 .   ? 32.011  -28.985 16.074  1    44.839 ? 1688 HOH A O      1 ? 
HETATM 5777 H H1     . HOH D 4 .   ? 32.762  -28.982 15.445  1    38.998 ? 1688 HOH A H1     1 ? 
HETATM 5778 H H2     . HOH D 4 .   ? 32.146  -29.68  16.755  1    42.669 ? 1688 HOH A H2     1 ? 
HETATM 5779 O O      . HOH D 4 .   ? 29.88   -20.471 17.965  1    15.677 ? 1689 HOH A O      1 ? 
HETATM 5780 H H1     . HOH D 4 .   ? 29.809  -19.785 18.648  1    16.076 ? 1689 HOH A H1     1 ? 
HETATM 5781 H H2     . HOH D 4 .   ? 29.033  -20.926 17.917  1    15.554 ? 1689 HOH A H2     1 ? 
HETATM 5782 O O      . HOH D 4 .   ? 8.027   -30.29  31.95   1    25.651 ? 1690 HOH A O      1 ? 
HETATM 5783 H H1     . HOH D 4 .   ? 8.929   -30.657 32.044  1    26.562 ? 1690 HOH A H1     1 ? 
HETATM 5784 H H2     . HOH D 4 .   ? 7.425   -31.04  31.781  1    23.628 ? 1690 HOH A H2     1 ? 
HETATM 5785 O O      . HOH D 4 .   ? 29.071  -27.333 4.066   1    44.98  ? 1691 HOH A O      1 ? 
HETATM 5786 H H1     . HOH D 4 .   ? 29.449  -26.666 4.669   1    44.642 ? 1691 HOH A H1     1 ? 
HETATM 5787 H H2     . HOH D 4 .   ? 28.538  -26.85  3.41    1    40.551 ? 1691 HOH A H2     1 ? 
HETATM 5788 O O      . HOH D 4 .   ? 22.999  -16.993 -9.35   1    27.002 ? 1692 HOH A O      1 ? 
HETATM 5789 H H1     . HOH D 4 .   ? 23.5    -16.187 -9.551  1    27.525 ? 1692 HOH A H1     1 ? 
HETATM 5790 H H2     . HOH D 4 .   ? 23.454  -17.425 -8.607  1    27.453 ? 1692 HOH A H2     1 ? 
HETATM 5791 O O      . HOH D 4 .   ? 26.604  -10.959 -11.73  1    30.851 ? 1693 HOH A O      1 ? 
HETATM 5792 H H1     . HOH D 4 .   ? 25.761  -11.432 -11.842 1    27.901 ? 1693 HOH A H1     1 ? 
HETATM 5793 H H2     . HOH D 4 .   ? 26.902  -11.098 -10.81  1    30.352 ? 1693 HOH A H2     1 ? 
HETATM 5794 O O      . HOH D 4 .   ? 3.712   -31.33  17.36   1    37.61  ? 1694 HOH A O      1 ? 
HETATM 5795 H H1     . HOH D 4 .   ? 4.279   -32.096 17.152  1    33.232 ? 1694 HOH A H1     1 ? 
HETATM 5796 H H2     . HOH D 4 .   ? 4.08    -30.534 16.924  1    33.921 ? 1694 HOH A H2     1 ? 
HETATM 5797 O O      . HOH D 4 .   ? 14.964  -45.354 19.669  1    44.186 ? 1695 HOH A O      1 ? 
HETATM 5798 H H1     . HOH D 4 .   ? 14.059  -45.665 19.872  1    43.556 ? 1695 HOH A H1     1 ? 
HETATM 5799 H H2     . HOH D 4 .   ? 15.058  -45.303 18.697  1    41.964 ? 1695 HOH A H2     1 ? 
HETATM 5800 O O      . HOH D 4 .   ? 37.717  -12.211 25.441  1    33.464 ? 1696 HOH A O      1 ? 
HETATM 5801 H H1     . HOH D 4 .   ? 38.362  -11.508 25.624  1    32.287 ? 1696 HOH A H1     1 ? 
HETATM 5802 H H2     . HOH D 4 .   ? 37.667  -12.316 24.468  1    29.8   ? 1696 HOH A H2     1 ? 
HETATM 5803 O O      . HOH D 4 .   ? 29.963  -29.764 18.75   1    32.883 ? 1697 HOH A O      1 ? 
HETATM 5804 H H1     . HOH D 4 .   ? 29.845  -30.154 19.641  1    29.46  ? 1697 HOH A H1     1 ? 
HETATM 5805 H H2     . HOH D 4 .   ? 30.738  -29.164 18.793  1    37.263 ? 1697 HOH A H2     1 ? 
HETATM 5806 O O      . HOH D 4 .   ? 26.636  -21.355 -11.145 1    33.865 ? 1698 HOH A O      1 ? 
HETATM 5807 H H1     . HOH D 4 .   ? 26.364  -21.707 -12.013 1    34.022 ? 1698 HOH A H1     1 ? 
HETATM 5808 H H2     . HOH D 4 .   ? 27.486  -21.775 -10.928 1    33.693 ? 1698 HOH A H2     1 ? 
HETATM 5809 O O      . HOH D 4 .   ? 5.799   -9.542  -4.418  1    44.987 ? 1699 HOH A O      1 ? 
HETATM 5810 H H1     . HOH D 4 .   ? 6.756   -9.4    -4.555  1    43.453 ? 1699 HOH A H1     1 ? 
HETATM 5811 H H2     . HOH D 4 .   ? 5.63    -9.627  -3.45   1    47.477 ? 1699 HOH A H2     1 ? 
HETATM 5812 O O      . HOH D 4 .   ? 16.74   -29.078 9.103   1    27.167 ? 1700 HOH A O      1 ? 
HETATM 5813 H H1     . HOH D 4 .   ? 16.045  -28.403 9.198   1    25.217 ? 1700 HOH A H1     1 ? 
HETATM 5814 H H2     . HOH D 4 .   ? 16.32   -29.868 8.719   1    27.523 ? 1700 HOH A H2     1 ? 
HETATM 5815 O O      . HOH D 4 .   ? 20.848  -38.332 30.317  1    24.437 ? 1701 HOH A O      1 ? 
HETATM 5816 H H1     . HOH D 4 .   ? 21.546  -37.911 30.849  1    23.471 ? 1701 HOH A H1     1 ? 
HETATM 5817 H H2     . HOH D 4 .   ? 21.226  -39.167 29.954  1    23.825 ? 1701 HOH A H2     1 ? 
HETATM 5818 O O      . HOH D 4 .   ? 27.444  -1.757  7.19    1    20.693 ? 1702 HOH A O      1 ? 
HETATM 5819 H H1     . HOH D 4 .   ? 26.921  -2.462  7.588   1    21.498 ? 1702 HOH A H1     1 ? 
HETATM 5820 H H2     . HOH D 4 .   ? 28.356  -1.942  7.458   1    21.703 ? 1702 HOH A H2     1 ? 
HETATM 5821 O O      . HOH D 4 .   ? -15.669 -21.705 18.447  1    23.262 ? 1703 HOH A O      1 ? 
HETATM 5822 H H1     . HOH D 4 .   ? -16.417 -22.125 18.922  1    22.877 ? 1703 HOH A H1     1 ? 
HETATM 5823 H H2     . HOH D 4 .   ? -15.582 -22.155 17.58   1    21.95  ? 1703 HOH A H2     1 ? 
HETATM 5824 O O      . HOH D 4 .   ? 27.422  -28.264 24.973  1    17.231 ? 1704 HOH A O      1 ? 
HETATM 5825 H H1     . HOH D 4 .   ? 27.06   -27.781 24.19   1    18.265 ? 1704 HOH A H1     1 ? 
HETATM 5826 H H2     . HOH D 4 .   ? 27.388  -27.632 25.7    1    17.226 ? 1704 HOH A H2     1 ? 
HETATM 5827 O O      . HOH D 4 .   ? 38.207  -20.89  26.173  1    22.078 ? 1705 HOH A O      1 ? 
HETATM 5828 H H1     . HOH D 4 .   ? 38.503  -21.184 25.29   1    23.728 ? 1705 HOH A H1     1 ? 
HETATM 5829 H H2     . HOH D 4 .   ? 37.258  -20.843 26.091  1    21.995 ? 1705 HOH A H2     1 ? 
HETATM 5830 O O      . HOH D 4 .   ? 14.456  -27.91  -2.638  1    50.69  ? 1706 HOH A O      1 ? 
HETATM 5831 H H1     . HOH D 4 .   ? 14.618  -27.973 -1.677  1    46.507 ? 1706 HOH A H1     1 ? 
HETATM 5832 H H2     . HOH D 4 .   ? 13.676  -28.452 -2.847  1    49.454 ? 1706 HOH A H2     1 ? 
HETATM 5833 O O      . HOH D 4 .   ? 20.843  -25.945 -1.227  1    28.986 ? 1707 HOH A O      1 ? 
HETATM 5834 H H1     . HOH D 4 .   ? 21.393  -25.63  -0.476  1    29.356 ? 1707 HOH A H1     1 ? 
HETATM 5835 H H2     . HOH D 4 .   ? 20.101  -25.323 -1.339  1    28.657 ? 1707 HOH A H2     1 ? 
HETATM 5836 O O      . HOH D 4 .   ? 4.822   -22.95  31.995  1    13.598 ? 1708 HOH A O      1 ? 
HETATM 5837 H H1     . HOH D 4 .   ? 5.605   -23.406 32.322  1    13.938 ? 1708 HOH A H1     1 ? 
HETATM 5838 H H2     . HOH D 4 .   ? 5.026   -22.827 31.07   1    13.252 ? 1708 HOH A H2     1 ? 
HETATM 5839 O O      . HOH D 4 .   ? 16.55   -1.55   -6.223  1    37.471 ? 1709 HOH A O      1 ? 
HETATM 5840 H H1     . HOH D 4 .   ? 17.088  -0.866  -6.661  1    38.919 ? 1709 HOH A H1     1 ? 
HETATM 5841 H H2     . HOH D 4 .   ? 15.764  -1.098  -5.873  1    34.901 ? 1709 HOH A H2     1 ? 
HETATM 5842 O O      . HOH D 4 .   ? 29.852  -17.621 -0.606  1    20.128 ? 1710 HOH A O      1 ? 
HETATM 5843 H H1     . HOH D 4 .   ? 29.984  -16.706 -0.987  1    18.294 ? 1710 HOH A H1     1 ? 
HETATM 5844 H H2     . HOH D 4 .   ? 28.948  -17.927 -0.887  1    19.887 ? 1710 HOH A H2     1 ? 
HETATM 5845 O O      . HOH D 4 .   ? 16.131  -36.604 12.73   1    40.112 ? 1711 HOH A O      1 ? 
HETATM 5846 H H1     . HOH D 4 .   ? 15.981  -35.661 12.941  1    41.424 ? 1711 HOH A H1     1 ? 
HETATM 5847 H H2     . HOH D 4 .   ? 16.522  -37.029 13.521  1    41.755 ? 1711 HOH A H2     1 ? 
HETATM 5848 O O      . HOH D 4 .   ? -1.166  -19.14  28.599  1    28.572 ? 1712 HOH A O      1 ? 
HETATM 5849 H H1     . HOH D 4 .   ? -1.012  -19.191 27.64   1    28.296 ? 1712 HOH A H1     1 ? 
HETATM 5850 H H2     . HOH D 4 .   ? -1.287  -18.187 28.846  1    27.545 ? 1712 HOH A H2     1 ? 
HETATM 5851 O O      . HOH D 4 .   ? 7.123   -6.977  7.729   1    22.965 ? 1713 HOH A O      1 ? 
HETATM 5852 H H1     . HOH D 4 .   ? 6.987   -6.436  6.921   1    26.613 ? 1713 HOH A H1     1 ? 
HETATM 5853 H H2     . HOH D 4 .   ? 7.903   -6.582  8.133   1    24.276 ? 1713 HOH A H2     1 ? 
HETATM 5854 O O      . HOH D 4 .   ? 14.127  -7.961  21.311  1    16.428 ? 1714 HOH A O      1 ? 
HETATM 5855 H H1     . HOH D 4 .   ? 14.371  -7.485  22.14   1    16.249 ? 1714 HOH A H1     1 ? 
HETATM 5856 H H2     . HOH D 4 .   ? 13.161  -7.994  21.236  1    15.322 ? 1714 HOH A H2     1 ? 
HETATM 5857 O O      . HOH D 4 .   ? 13.827  -34.387 18.538  1    33.12  ? 1715 HOH A O      1 ? 
HETATM 5858 H H1     . HOH D 4 .   ? 14.028  -33.438 18.361  1    29.71  ? 1715 HOH A H1     1 ? 
HETATM 5859 H H2     . HOH D 4 .   ? 12.892  -34.57  18.312  1    33.699 ? 1715 HOH A H2     1 ? 
HETATM 5860 O O      . HOH D 4 .   ? 5.239   -26.359 13.09   1    30.271 ? 1716 HOH A O      1 ? 
HETATM 5861 H H1     . HOH D 4 .   ? 5.259   -25.873 13.951  1    28.053 ? 1716 HOH A H1     1 ? 
HETATM 5862 H H2     . HOH D 4 .   ? 5.421   -27.3   13.27   1    29.073 ? 1716 HOH A H2     1 ? 
HETATM 5863 O O      . HOH D 4 .   ? 1.26    -32.244 17.382  1    32.156 ? 1717 HOH A O      1 ? 
HETATM 5864 H H1     . HOH D 4 .   ? 1.949   -32.033 16.734  1    30.311 ? 1717 HOH A H1     1 ? 
HETATM 5865 H H2     . HOH D 4 .   ? 0.761   -31.422 17.558  1    31.89  ? 1717 HOH A H2     1 ? 
HETATM 5866 O O      . HOH D 4 .   ? 31.202  -21.991 3.205   1    21.123 ? 1718 HOH A O      1 ? 
HETATM 5867 H H1     . HOH D 4 .   ? 31.322  -21.345 2.514   1    21.947 ? 1718 HOH A H1     1 ? 
HETATM 5868 H H2     . HOH D 4 .   ? 31.138  -21.443 3.997   1    22.555 ? 1718 HOH A H2     1 ? 
HETATM 5869 O O      . HOH D 4 .   ? 13.012  -33.617 14.610  1    37.059 ? 1719 HOH A O      1 ? 
HETATM 5870 H H1     . HOH D 4 .   ? 12.290  -33.440 13.983  1    36.957 ? 1719 HOH A H1     1 ? 
HETATM 5871 H H2     . HOH D 4 .   ? 13.843  -33.390 14.157  1    37.415 ? 1719 HOH A H2     1 ? 
HETATM 5872 O O      . HOH D 4 .   ? 15.036  -28.391 12.036  1    28.989 ? 1720 HOH A O      1 ? 
HETATM 5873 H H1     . HOH D 4 .   ? 15.847  -27.942 12.395  1    26.352 ? 1720 HOH A H1     1 ? 
HETATM 5874 H H2     . HOH D 4 .   ? 14.919  -29.262 12.48   1    25.144 ? 1720 HOH A H2     1 ? 
HETATM 5875 O O      . HOH D 4 .   ? 35.859  -16.006 15.996  1    13.932 ? 1721 HOH A O      1 ? 
HETATM 5876 H H1     . HOH D 4 .   ? 36.01   -16.439 15.155  1    14.795 ? 1721 HOH A H1     1 ? 
HETATM 5877 H H2     . HOH D 4 .   ? 35.268  -15.249 15.795  1    14.807 ? 1721 HOH A H2     1 ? 
HETATM 5878 O O      . HOH D 4 .   ? 6.579   -33.359 29.182  1    39.066 ? 1722 HOH A O      1 ? 
HETATM 5879 H H1     . HOH D 4 .   ? 6.552   -34.288 28.893  1    37.015 ? 1722 HOH A H1     1 ? 
HETATM 5880 H H2     . HOH D 4 .   ? 6.976   -32.848 28.456  1    36.349 ? 1722 HOH A H2     1 ? 
HETATM 5881 O O      . HOH D 4 .   ? 8.541   -27.577 36.108  1    14.153 ? 1723 HOH A O      1 ? 
HETATM 5882 H H1     . HOH D 4 .   ? 8.397   -28.526 36.025  1    15.375 ? 1723 HOH A H1     1 ? 
HETATM 5883 H H2     . HOH D 4 .   ? 8.013   -27.231 35.397  1    15.123 ? 1723 HOH A H2     1 ? 
HETATM 5884 O O      . HOH D 4 .   ? 19.322  -6.61   21.484  1    35.87  ? 1724 HOH A O      1 ? 
HETATM 5885 H H1     . HOH D 4 .   ? 20.033  -6.972  22.049  1    33.184 ? 1724 HOH A H1     1 ? 
HETATM 5886 H H2     . HOH D 4 .   ? 18.451  -6.872  21.844  1    34.75  ? 1724 HOH A H2     1 ? 
HETATM 5887 O O      . HOH D 4 .   ? 0.739   -7.542  9.787   1    73.583 ? 1725 HOH A O      1 ? 
HETATM 5888 H H1     . HOH D 4 .   ? 0.862   -6.617  9.505   1    70.809 ? 1725 HOH A H1     1 ? 
HETATM 5889 H H2     . HOH D 4 .   ? 1.331   -7.709  10.541  1    74.167 ? 1725 HOH A H2     1 ? 
HETATM 5890 O O      . HOH D 4 .   ? 2.697   -6.135  -0.15   1    36.423 ? 1726 HOH A O      1 ? 
HETATM 5891 H H1     . HOH D 4 .   ? 3.106   -5.61   0.571   1    37.012 ? 1726 HOH A H1     1 ? 
HETATM 5892 H H2     . HOH D 4 .   ? 1.731   -6.099  -0.033  1    36.495 ? 1726 HOH A H2     1 ? 
HETATM 5893 O O      . HOH D 4 .   ? 2.169   -19.166 7.338   1    23.308 ? 1727 HOH A O      1 ? 
HETATM 5894 H H1     . HOH D 4 .   ? 2.591   -19.856 7.903   1    21.802 ? 1727 HOH A H1     1 ? 
HETATM 5895 H H2     . HOH D 4 .   ? 2.122   -18.327 7.833   1    22.158 ? 1727 HOH A H2     1 ? 
HETATM 5896 O O      . HOH D 4 .   ? -16.731 -17.208 14.638  1    41.358 ? 1728 HOH A O      1 ? 
HETATM 5897 H H1     . HOH D 4 .   ? -16.204 -16.688 15.276  1    39.011 ? 1728 HOH A H1     1 ? 
HETATM 5898 H H2     . HOH D 4 .   ? -16.857 -18.118 14.99   1    37.712 ? 1728 HOH A H2     1 ? 
HETATM 5899 O O      . HOH D 4 .   ? 12.867  -4.269  -17.191 1    53.157 ? 1729 HOH A O      1 ? 
HETATM 5900 H H1     . HOH D 4 .   ? 13.041  -3.486  -16.636 1    51.065 ? 1729 HOH A H1     1 ? 
HETATM 5901 H H2     . HOH D 4 .   ? 13.713  -4.739  -17.312 1    50.305 ? 1729 HOH A H2     1 ? 
HETATM 5902 O O      . HOH D 4 .   ? 21.043  -3.002  -5.313  1    24.713 ? 1730 HOH A O      1 ? 
HETATM 5903 H H1     . HOH D 4 .   ? 20.532  -2.433  -5.933  1    23.818 ? 1730 HOH A H1     1 ? 
HETATM 5904 H H2     . HOH D 4 .   ? 21.453  -2.426  -4.643  1    24.155 ? 1730 HOH A H2     1 ? 
HETATM 5905 O O      . HOH D 4 .   ? 26.856  -27.188 22.6    1    18.204 ? 1731 HOH A O      1 ? 
HETATM 5906 H H1     . HOH D 4 .   ? 27.426  -27.444 21.838  1    22.117 ? 1731 HOH A H1     1 ? 
HETATM 5907 H H2     . HOH D 4 .   ? 26.632  -26.295 22.356  1    18.302 ? 1731 HOH A H2     1 ? 
HETATM 5908 O O      . HOH D 4 .   ? 23.973  0.454   -1.425  1    34.242 ? 1732 HOH A O      1 ? 
HETATM 5909 H H1     . HOH D 4 .   ? 23.229  1.001   -1.745  1    33.498 ? 1732 HOH A H1     1 ? 
HETATM 5910 H H2     . HOH D 4 .   ? 24      -0.359  -1.964  1    30.292 ? 1732 HOH A H2     1 ? 
HETATM 5911 O O      . HOH D 4 .   ? 10.908  -15.377 33.865  1    36.563 ? 1733 HOH A O      1 ? 
HETATM 5912 H H1     . HOH D 4 .   ? 11.64   -15.603 34.462  1    37.399 ? 1733 HOH A H1     1 ? 
HETATM 5913 H H2     . HOH D 4 .   ? 10.213  -15.022 34.436  1    36.419 ? 1733 HOH A H2     1 ? 
HETATM 5914 O O      . HOH D 4 .   ? 10.913  -0.529  19.211  1    40.437 ? 1734 HOH A O      1 ? 
HETATM 5915 H H1     . HOH D 4 .   ? 11.766  -0.136  18.951  1    39.368 ? 1734 HOH A H1     1 ? 
HETATM 5916 H H2     . HOH D 4 .   ? 10.28   0.199   19.359  1    39.897 ? 1734 HOH A H2     1 ? 
HETATM 5917 O O      . HOH D 4 .   ? -13.914 -20.854 21.046  1    26.53  ? 1735 HOH A O      1 ? 
HETATM 5918 H H1     . HOH D 4 .   ? -13.471 -21.364 21.747  1    23.348 ? 1735 HOH A H1     1 ? 
HETATM 5919 H H2     . HOH D 4 .   ? -13.549 -19.929 21.054  1    25.776 ? 1735 HOH A H2     1 ? 
HETATM 5920 O O      . HOH D 4 .   ? 26.867  -5.73   -3.019  1    36.311 ? 1736 HOH A O      1 ? 
HETATM 5921 H H1     . HOH D 4 .   ? 27.742  -5.907  -2.603  1    33.053 ? 1736 HOH A H1     1 ? 
HETATM 5922 H H2     . HOH D 4 .   ? 26.736  -4.757  -3.052  1    35.827 ? 1736 HOH A H2     1 ? 
HETATM 5923 O O      . HOH D 4 .   ? 31.321  -27.118 13.667  1    35.799 ? 1737 HOH A O      1 ? 
HETATM 5924 H H1     . HOH D 4 .   ? 31.995  -27.714 14.072  1    30.219 ? 1737 HOH A H1     1 ? 
HETATM 5925 H H2     . HOH D 4 .   ? 31.322  -27.191 12.687  1    30.885 ? 1737 HOH A H2     1 ? 
HETATM 5926 O O      . HOH D 4 .   ? 37.378  -25.137 12.159  1    41.234 ? 1738 HOH A O      1 ? 
HETATM 5927 H H1     . HOH D 4 .   ? 38.101  -25.574 11.659  1    41.606 ? 1738 HOH A H1     1 ? 
HETATM 5928 H H2     . HOH D 4 .   ? 36.557  -25.67  12.08   1    37.682 ? 1738 HOH A H2     1 ? 
HETATM 5929 O O      . HOH D 4 .   ? 4.053   -13.75  1.146   1    31.222 ? 1739 HOH A O      1 ? 
HETATM 5930 H H1     . HOH D 4 .   ? 4.336   -13.311 1.976   1    30.332 ? 1739 HOH A H1     1 ? 
HETATM 5931 H H2     . HOH D 4 .   ? 3.983   -14.715 1.306   1    28.679 ? 1739 HOH A H2     1 ? 
HETATM 5932 O O      . HOH D 4 .   ? 29.143  -13.535 -3.293  1    21.243 ? 1740 HOH A O      1 ? 
HETATM 5933 H H1     . HOH D 4 .   ? 29.561  -12.674 -3.435  1    22.849 ? 1740 HOH A H1     1 ? 
HETATM 5934 H H2     . HOH D 4 .   ? 28.364  -13.511 -3.871  1    22.107 ? 1740 HOH A H2     1 ? 
HETATM 5935 O O      . HOH D 4 .   ? -13.759 -18.12  21.47   1    34.083 ? 1741 HOH A O      1 ? 
HETATM 5936 H H1     . HOH D 4 .   ? -13.423 -17.203 21.568  1    33.084 ? 1741 HOH A H1     1 ? 
HETATM 5937 H H2     . HOH D 4 .   ? -13.84  -18.498 22.364  1    31.853 ? 1741 HOH A H2     1 ? 
HETATM 5938 O O      . HOH D 4 .   ? 39.66   -17.06  8.303   1    35.697 ? 1742 HOH A O      1 ? 
HETATM 5939 H H1     . HOH D 4 .   ? 40.29   -17.797 8.356   1    33.522 ? 1742 HOH A H1     1 ? 
HETATM 5940 H H2     . HOH D 4 .   ? 39.947  -16.486 7.569   1    33.787 ? 1742 HOH A H2     1 ? 
HETATM 5941 O O      . HOH D 4 .   ? 28.037  -29.232 33.189  1    37.722 ? 1743 HOH A O      1 ? 
HETATM 5942 H H1     . HOH D 4 .   ? 28.859  -28.761 32.929  1    33.254 ? 1743 HOH A H1     1 ? 
HETATM 5943 H H2     . HOH D 4 .   ? 27.46   -29.309 32.405  1    33.798 ? 1743 HOH A H2     1 ? 
HETATM 5944 O O      . HOH D 4 .   ? 37.131  -8.633  6.518   1    31.188 ? 1744 HOH A O      1 ? 
HETATM 5945 H H1     . HOH D 4 .   ? 37.856  -9.075  6.039   1    29.984 ? 1744 HOH A H1     1 ? 
HETATM 5946 H H2     . HOH D 4 .   ? 36.945  -7.771  6.089   1    30.207 ? 1744 HOH A H2     1 ? 
HETATM 5947 O O      . HOH D 4 .   ? 23      -2.241  6.099   1    19.806 ? 1745 HOH A O      1 ? 
HETATM 5948 H H1     . HOH D 4 .   ? 23.95   -2.123  5.951   1    20.815 ? 1745 HOH A H1     1 ? 
HETATM 5949 H H2     . HOH D 4 .   ? 22.753  -1.648  6.841   1    18.511 ? 1745 HOH A H2     1 ? 
HETATM 5950 O O      . HOH D 4 .   ? 6.233   -17.92  14.975  1    22.912 ? 1746 HOH A O      1 ? 
HETATM 5951 H H1     . HOH D 4 .   ? 5.976   -18.83  14.701  1    22.672 ? 1746 HOH A H1     1 ? 
HETATM 5952 H H2     . HOH D 4 .   ? 7.215   -17.87  14.955  1    22.173 ? 1746 HOH A H2     1 ? 
HETATM 5953 O O      . HOH D 4 .   ? 30.84   -30.542 27.139  1    35.199 ? 1747 HOH A O      1 ? 
HETATM 5954 H H1     . HOH D 4 .   ? 30.46   -30.643 26.253  1    36.313 ? 1747 HOH A H1     1 ? 
HETATM 5955 H H2     . HOH D 4 .   ? 30.612  -29.646 27.428  1    36.618 ? 1747 HOH A H2     1 ? 
HETATM 5956 O O      . HOH D 4 .   ? 33.308  -7.991  18.495  1    50.945 ? 1748 HOH A O      1 ? 
HETATM 5957 H H1     . HOH D 4 .   ? 32.709  -7.225  18.401  1    52.253 ? 1748 HOH A H1     1 ? 
HETATM 5958 H H2     . HOH D 4 .   ? 32.761  -8.784  18.653  1    44.671 ? 1748 HOH A H2     1 ? 
HETATM 5959 O O      . HOH D 4 .   ? -21.703 -9.452  13.627  1    49.807 ? 1749 HOH A O      1 ? 
HETATM 5960 H H1     . HOH D 4 .   ? -21.701 -9.989  12.817  1    45.693 ? 1749 HOH A H1     1 ? 
HETATM 5961 H H2     . HOH D 4 .   ? -20.968 -9.756  14.194  1    51.005 ? 1749 HOH A H2     1 ? 
HETATM 5962 O O      . HOH D 4 .   ? 10.999  3.686   10.317  1    52.757 ? 1750 HOH A O      1 ? 
HETATM 5963 H H1     . HOH D 4 .   ? 10.035  3.572   10.219  1    54.858 ? 1750 HOH A H1     1 ? 
HETATM 5964 H H2     . HOH D 4 .   ? 11.169  4.031   11.214  1    52.826 ? 1750 HOH A H2     1 ? 
HETATM 5965 O O      . HOH D 4 .   ? -0.521  -5.888  1.893   1    30.664 ? 1751 HOH A O      1 ? 
HETATM 5966 H H1     . HOH D 4 .   ? -0.038  -6.576  1.393   1    30.019 ? 1751 HOH A H1     1 ? 
HETATM 5967 H H2     . HOH D 4 .   ? -0.706  -5.158  1.264   1    27.589 ? 1751 HOH A H2     1 ? 
HETATM 5968 O O      . HOH D 4 .   ? -6.21   -20.894 14.694  1    30.832 ? 1752 HOH A O      1 ? 
HETATM 5969 H H1     . HOH D 4 .   ? -6.339  -20.561 15.611  1    33.306 ? 1752 HOH A H1     1 ? 
HETATM 5970 H H2     . HOH D 4 .   ? -6.291  -21.868 14.74   1    26.731 ? 1752 HOH A H2     1 ? 
HETATM 5971 O O      . HOH D 4 .   ? 24.945  -18.759 -8.656  1    27.523 ? 1753 HOH A O      1 ? 
HETATM 5972 H H1     . HOH D 4 .   ? 25.845  -18.69  -9.013  1    29.467 ? 1753 HOH A H1     1 ? 
HETATM 5973 H H2     . HOH D 4 .   ? 24.888  -19.622 -8.208  1    29.057 ? 1753 HOH A H2     1 ? 
HETATM 5974 O O      . HOH D 4 .   ? 35.773  -12.409 27.503  1    31.552 ? 1754 HOH A O      1 ? 
HETATM 5975 H H1     . HOH D 4 .   ? 35.377  -11.603 27.117  1    30.313 ? 1754 HOH A H1     1 ? 
HETATM 5976 H H2     . HOH D 4 .   ? 35.233  -12.673 28.268  1    27.057 ? 1754 HOH A H2     1 ? 
HETATM 5977 O O      . HOH D 4 .   ? -1.48   -12.676 20.403  1    48.081 ? 1755 HOH A O      1 ? 
HETATM 5978 H H1     . HOH D 4 .   ? -1.655  -11.769 20.087  1    48.399 ? 1755 HOH A H1     1 ? 
HETATM 5979 H H2     . HOH D 4 .   ? -2.032  -12.823 21.191  1    42.56  ? 1755 HOH A H2     1 ? 
HETATM 5980 O O      . HOH D 4 .   ? 14.755  -5.689  20.045  1    17.812 ? 1756 HOH A O      1 ? 
HETATM 5981 H H1     . HOH D 4 .   ? 14.32   -5.058  19.44   1    18.155 ? 1756 HOH A H1     1 ? 
HETATM 5982 H H2     . HOH D 4 .   ? 14.09   -6.341  20.303  1    17.312 ? 1756 HOH A H2     1 ? 
HETATM 5983 O O      . HOH D 4 .   ? 18.34   -27.176 10.437  1    17.675 ? 1757 HOH A O      1 ? 
HETATM 5984 H H1     . HOH D 4 .   ? 19.277  -27.137 10.675  1    17.965 ? 1757 HOH A H1     1 ? 
HETATM 5985 H H2     . HOH D 4 .   ? 18.006  -26.275 10.618  1    19.11  ? 1757 HOH A H2     1 ? 
HETATM 5986 O O      . HOH D 4 .   ? 6.318   -37.95  22.439  1    43.794 ? 1758 HOH A O      1 ? 
HETATM 5987 H H1     . HOH D 4 .   ? 6.104   -37.112 22.893  1    39.699 ? 1758 HOH A H1     1 ? 
HETATM 5988 H H2     . HOH D 4 .   ? 6.222   -37.81  21.473  1    38.339 ? 1758 HOH A H2     1 ? 
HETATM 5989 O O      . HOH D 4 .   ? 11.268  -14.556 -14.035 1    27.57  ? 1759 HOH A O      1 ? 
HETATM 5990 H H1     . HOH D 4 .   ? 11.878  -14.329 -14.754 1    26.897 ? 1759 HOH A H1     1 ? 
HETATM 5991 H H2     . HOH D 4 .   ? 11.208  -13.788 -13.425 1    26.973 ? 1759 HOH A H2     1 ? 
HETATM 5992 O O      . HOH D 4 .   ? 38.249  -12.519 9.705   1    40.295 ? 1760 HOH A O      1 ? 
HETATM 5993 H H1     . HOH D 4 .   ? 38.643  -12.233 8.857   1    39.544 ? 1760 HOH A H1     1 ? 
HETATM 5994 H H2     . HOH D 4 .   ? 38.949  -12.966 10.214  1    38.678 ? 1760 HOH A H2     1 ? 
HETATM 5995 O O      . HOH D 4 .   ? 32.924  -33.154 25.400  1    46.768 ? 1761 HOH A O      1 ? 
HETATM 5996 H H1     . HOH D 4 .   ? 32.977  -33.448 26.333  1    41.388 ? 1761 HOH A H1     1 ? 
HETATM 5997 H H2     . HOH D 4 .   ? 33.638  -33.600 24.891  1    42.967 ? 1761 HOH A H2     1 ? 
HETATM 5998 O O      . HOH D 4 .   ? -1.401  -8.21   3.145   1    45.807 ? 1762 HOH A O      1 ? 
HETATM 5999 H H1     . HOH D 4 .   ? -0.76   -7.494  3.002   1    44.199 ? 1762 HOH A H1     1 ? 
HETATM 6000 H H2     . HOH D 4 .   ? -1.956  -7.956  3.903   1    44.958 ? 1762 HOH A H2     1 ? 
HETATM 6001 O O      . HOH D 4 .   ? 8.573   4.852   5.508   1    32.861 ? 1763 HOH A O      1 ? 
HETATM 6002 H H1     . HOH D 4 .   ? 7.714   5.299   5.604   1    28.598 ? 1763 HOH A H1     1 ? 
HETATM 6003 H H2     . HOH D 4 .   ? 9.246   5.546   5.43    1    30.71  ? 1763 HOH A H2     1 ? 
HETATM 6004 O O      . HOH D 4 .   ? 17.816  -34.357 11.392  1    30.792 ? 1764 HOH A O      1 ? 
HETATM 6005 H H1     . HOH D 4 .   ? 17.49   -33.715 10.736  1    32.265 ? 1764 HOH A H1     1 ? 
HETATM 6006 H H2     . HOH D 4 .   ? 17.076  -34.557 11.992  1    31.643 ? 1764 HOH A H2     1 ? 
HETATM 6007 O O      . HOH D 4 .   ? 23.229  -10.093 25.345  1    32.839 ? 1765 HOH A O      1 ? 
HETATM 6008 H H1     . HOH D 4 .   ? 22.264  -10.196 25.536  1    29.145 ? 1765 HOH A H1     1 ? 
HETATM 6009 H H2     . HOH D 4 .   ? 23.71   -9.776  26.139  1    31.853 ? 1765 HOH A H2     1 ? 
HETATM 6010 O O      . HOH D 4 .   ? -1.03   -4.99   21.239  1    38.135 ? 1766 HOH A O      1 ? 
HETATM 6011 H H1     . HOH D 4 .   ? -0.239  -4.456  21.458  1    37.198 ? 1766 HOH A H1     1 ? 
HETATM 6012 H H2     . HOH D 4 .   ? -1.491  -5.181  22.075  1    36.378 ? 1766 HOH A H2     1 ? 
HETATM 6013 O O      . HOH D 4 .   ? 16.65   -25.544 1.009   1    36.582 ? 1767 HOH A O      1 ? 
HETATM 6014 H H1     . HOH D 4 .   ? 17.378  -24.905 0.872   1    36.375 ? 1767 HOH A H1     1 ? 
HETATM 6015 H H2     . HOH D 4 .   ? 16.89   -26.091 1.778   1    37.102 ? 1767 HOH A H2     1 ? 
HETATM 6016 O O      . HOH D 4 .   ? 16.544  -0.806  7.864   1    28.843 ? 1768 HOH A O      1 ? 
HETATM 6017 H H1     . HOH D 4 .   ? 16.516  -0.738  6.898   1    28.298 ? 1768 HOH A H1     1 ? 
HETATM 6018 H H2     . HOH D 4 .   ? 15.62   -0.731  8.169   1    28.409 ? 1768 HOH A H2     1 ? 
HETATM 6019 O O      . HOH D 4 .   ? 13.903  0.136   12.93   1    29.062 ? 1769 HOH A O      1 ? 
HETATM 6020 H H1     . HOH D 4 .   ? 14.099  0.393   13.848  1    28.771 ? 1769 HOH A H1     1 ? 
HETATM 6021 H H2     . HOH D 4 .   ? 13.482  -0.748  12.98   1    30.665 ? 1769 HOH A H2     1 ? 
HETATM 6022 O O      . HOH D 4 .   ? -20.146 -9.849  16.647  1    43.627 ? 1770 HOH A O      1 ? 
HETATM 6023 H H1     . HOH D 4 .   ? -20.109 -10.817 16.523  1    42.704 ? 1770 HOH A H1     1 ? 
HETATM 6024 H H2     . HOH D 4 .   ? -20.178 -9.658  17.605  1    41.331 ? 1770 HOH A H2     1 ? 
HETATM 6025 O O      . HOH D 4 .   ? -15.89  -24.632 19.667  1    49.853 ? 1771 HOH A O      1 ? 
HETATM 6026 H H1     . HOH D 4 .   ? -15.487 -25.396 19.191  1    44.376 ? 1771 HOH A H1     1 ? 
HETATM 6027 H H2     . HOH D 4 .   ? -15.688 -24.669 20.64   1    45.151 ? 1771 HOH A H2     1 ? 
HETATM 6028 O O      . HOH D 4 .   ? 36.131  -4.499  12.441  1    49.489 ? 1772 HOH A O      1 ? 
HETATM 6029 H H1     . HOH D 4 .   ? 35.556  -3.868  12.903  1    46.582 ? 1772 HOH A H1     1 ? 
HETATM 6030 H H2     . HOH D 4 .   ? 36.113  -4.257  11.493  1    48.364 ? 1772 HOH A H2     1 ? 
HETATM 6031 O O      . HOH D 4 .   ? 18.856  -2.376  -7.092  1    37.145 ? 1773 HOH A O      1 ? 
HETATM 6032 H H1     . HOH D 4 .   ? 18.846  -1.653  -7.744  1    36.562 ? 1773 HOH A H1     1 ? 
HETATM 6033 H H2     . HOH D 4 .   ? 17.933  -2.655  -6.953  1    34.607 ? 1773 HOH A H2     1 ? 
HETATM 6034 O O      . HOH D 4 .   ? 19.759  -0.212  12.732  1    41.013 ? 1774 HOH A O      1 ? 
HETATM 6035 H H1     . HOH D 4 .   ? 19.271  -0.627  12.001  1    40.391 ? 1774 HOH A H1     1 ? 
HETATM 6036 H H2     . HOH D 4 .   ? 19.584  -0.735  13.537  1    40.117 ? 1774 HOH A H2     1 ? 
HETATM 6037 O O      . HOH D 4 .   ? 22.449  0.263   3.001   1    32.188 ? 1775 HOH A O      1 ? 
HETATM 6038 H H1     . HOH D 4 .   ? 23.216  0.315   2.414   1    30.253 ? 1775 HOH A H1     1 ? 
HETATM 6039 H H2     . HOH D 4 .   ? 21.909  -0.499  2.708   1    33.582 ? 1775 HOH A H2     1 ? 
HETATM 6040 O O      . HOH D 4 .   ? 22.094  -13.296 25.767  1    28.152 ? 1776 HOH A O      1 ? 
HETATM 6041 H H1     . HOH D 4 .   ? 23.021  -12.967 25.869  1    28.411 ? 1776 HOH A H1     1 ? 
HETATM 6042 H H2     . HOH D 4 .   ? 21.465  -12.625 26.12   1    26.201 ? 1776 HOH A H2     1 ? 
HETATM 6043 O O      . HOH D 4 .   ? 17.407  -36.349 32.072  1    16.661 ? 1777 HOH A O      1 ? 
HETATM 6044 H H1     . HOH D 4 .   ? 17.454  -35.484 32.51   1    17.24  ? 1777 HOH A H1     1 ? 
HETATM 6045 H H2     . HOH D 4 .   ? 16.597  -36.753 32.415  1    17.413 ? 1777 HOH A H2     1 ? 
HETATM 6046 O O      . HOH D 4 .   ? 9.271   -10.058 30.455  1    27.654 ? 1778 HOH A O      1 ? 
HETATM 6047 H H1     . HOH D 4 .   ? 10.057  -9.458  30.418  1    24.639 ? 1778 HOH A H1     1 ? 
HETATM 6048 H H2     . HOH D 4 .   ? 8.528   -9.562  30.842  1    26.413 ? 1778 HOH A H2     1 ? 
HETATM 6049 O O      . HOH D 4 .   ? 6.501   -25.785 5.889   1    55.706 ? 1779 HOH A O      1 ? 
HETATM 6050 H H1     . HOH D 4 .   ? 7.31    -25.822 5.346   1    51.724 ? 1779 HOH A H1     1 ? 
HETATM 6051 H H2     . HOH D 4 .   ? 5.916   -26.517 5.61    1    57.465 ? 1779 HOH A H2     1 ? 
HETATM 6052 O O      . HOH D 4 .   ? 17.99   -22.099 36.754  1    37.642 ? 1780 HOH A O      1 ? 
HETATM 6053 H H1     . HOH D 4 .   ? 18.541  -22.906 36.694  1    37.195 ? 1780 HOH A H1     1 ? 
HETATM 6054 H H2     . HOH D 4 .   ? 17.176  -22.217 36.207  1    31.727 ? 1780 HOH A H2     1 ? 
HETATM 6055 O O      . HOH D 4 .   ? 20.314  -25.516 -13.101 1    23.787 ? 1781 HOH A O      1 ? 
HETATM 6056 H H1     . HOH D 4 .   ? 21.269  -25.726 -13.049 1    24.488 ? 1781 HOH A H1     1 ? 
HETATM 6057 H H2     . HOH D 4 .   ? 19.939  -26.027 -13.836 1    24.087 ? 1781 HOH A H2     1 ? 
HETATM 6058 O O      . HOH D 4 .   ? 24.777  -37.832 16.467  1    28.533 ? 1782 HOH A O      1 ? 
HETATM 6059 H H1     . HOH D 4 .   ? 24.841  -37.51  17.391  1    25.804 ? 1782 HOH A H1     1 ? 
HETATM 6060 H H2     . HOH D 4 .   ? 23.836  -38.072 16.265  1    25.987 ? 1782 HOH A H2     1 ? 
HETATM 6061 O O      . HOH D 4 .   ? 18.33   -11.174 25.165  1    41.812 ? 1783 HOH A O      1 ? 
HETATM 6062 H H1     . HOH D 4 .   ? 18.131  -10.786 26.035  1    45.219 ? 1783 HOH A H1     1 ? 
HETATM 6063 H H2     . HOH D 4 .   ? 18.359  -10.427 24.543  1    44.471 ? 1783 HOH A H2     1 ? 
HETATM 6064 O O      . HOH D 4 .   ? 11.616  -4.783  23.129  1    29.446 ? 1784 HOH A O      1 ? 
HETATM 6065 H H1     . HOH D 4 .   ? 11.423  -5.418  22.409  1    28.552 ? 1784 HOH A H1     1 ? 
HETATM 6066 H H2     . HOH D 4 .   ? 10.995  -4.036  23.029  1    29.331 ? 1784 HOH A H2     1 ? 
HETATM 6067 O O      . HOH D 4 .   ? 18.165  -5.108  -10.43  1    35.687 ? 1785 HOH A O      1 ? 
HETATM 6068 H H1     . HOH D 4 .   ? 18.605  -4.581  -11.113 1    35.146 ? 1785 HOH A H1     1 ? 
HETATM 6069 H H2     . HOH D 4 .   ? 17.468  -5.604  -10.893 1    36.415 ? 1785 HOH A H2     1 ? 
HETATM 6070 O O      . HOH D 4 .   ? 36.886  -6.732  10.135  1    54.06  ? 1786 HOH A O      1 ? 
HETATM 6071 H H1     . HOH D 4 .   ? 36.689  -7.694  10.179  1    50.784 ? 1786 HOH A H1     1 ? 
HETATM 6072 H H2     . HOH D 4 .   ? 37.033  -6.373  11.039  1    47.877 ? 1786 HOH A H2     1 ? 
HETATM 6073 O O      . HOH D 4 .   ? 20.917  -30.076 -5.16   1    42.385 ? 1787 HOH A O      1 ? 
HETATM 6074 H H1     . HOH D 4 .   ? 21.616  -29.918 -4.502  1    44.911 ? 1787 HOH A H1     1 ? 
HETATM 6075 H H2     . HOH D 4 .   ? 21.238  -29.722 -6.008  1    43.939 ? 1787 HOH A H2     1 ? 
HETATM 6076 O O      . HOH D 4 .   ? 28.01   -21.707 -6.253  1    48.428 ? 1788 HOH A O      1 ? 
HETATM 6077 H H1     . HOH D 4 .   ? 28.492  -21.19  -5.586  1    44.978 ? 1788 HOH A H1     1 ? 
HETATM 6078 H H2     . HOH D 4 .   ? 27.189  -21.22  -6.441  1    51.951 ? 1788 HOH A H2     1 ? 
HETATM 6079 O O      . HOH D 4 .   ? -6.822  -17.559 16.256  1    46.701 ? 1789 HOH A O      1 ? 
HETATM 6080 H H1     . HOH D 4 .   ? -6.007  -18.11  16.288  1    46.926 ? 1789 HOH A H1     1 ? 
HETATM 6081 H H2     . HOH D 4 .   ? -6.574  -16.618 16.087  1    43.726 ? 1789 HOH A H2     1 ? 
HETATM 6082 O O      . HOH D 4 .   ? 30.687  -26.03  11.28   1    42.697 ? 1790 HOH A O      1 ? 
HETATM 6083 H H1     . HOH D 4 .   ? 29.781  -26.116 10.919  1    39.537 ? 1790 HOH A H1     1 ? 
HETATM 6084 H H2     . HOH D 4 .   ? 31.287  -26.426 10.621  1    40.316 ? 1790 HOH A H2     1 ? 
HETATM 6085 O O      . HOH D 4 .   ? 30.002  -27.84  28.245  1    28.867 ? 1791 HOH A O      1 ? 
HETATM 6086 H H1     . HOH D 4 .   ? 30.293  -27.696 29.163  1    26.578 ? 1791 HOH A H1     1 ? 
HETATM 6087 H H2     . HOH D 4 .   ? 29.072  -28.141 28.269  1    28.453 ? 1791 HOH A H2     1 ? 
HETATM 6088 O O      . HOH D 4 .   ? 6.806   -36.674 18.572  1    30.261 ? 1792 HOH A O      1 ? 
HETATM 6089 H H1     . HOH D 4 .   ? 6.177   -36.066 18.125  1    28.046 ? 1792 HOH A H1     1 ? 
HETATM 6090 H H2     . HOH D 4 .   ? 6.39    -37.035 19.385  1    27.667 ? 1792 HOH A H2     1 ? 
HETATM 6091 O O      . HOH D 4 .   ? 28.228  -23.433 -2.195  1    37.579 ? 1793 HOH A O      1 ? 
HETATM 6092 H H1     . HOH D 4 .   ? 27.431  -23.115 -2.658  1    33.491 ? 1793 HOH A H1     1 ? 
HETATM 6093 H H2     . HOH D 4 .   ? 28.024  -24.323 -1.861  1    39.397 ? 1793 HOH A H2     1 ? 
HETATM 6094 O O      . HOH D 4 .   ? 6.533   -20.051 -2.023  1    27.081 ? 1794 HOH A O      1 ? 
HETATM 6095 H H1     . HOH D 4 .   ? 6.202   -20.454 -1.208  1    30.82  ? 1794 HOH A H1     1 ? 
HETATM 6096 H H2     . HOH D 4 .   ? 5.764   -20.01  -2.606  1    28.812 ? 1794 HOH A H2     1 ? 
HETATM 6097 O O      . HOH D 4 .   ? -9.028  -27.977 21.011  1    48.653 ? 1795 HOH A O      1 ? 
HETATM 6098 H H1     . HOH D 4 .   ? -8.515  -27.598 21.748  1    50.702 ? 1795 HOH A H1     1 ? 
HETATM 6099 H H2     . HOH D 4 .   ? -9.909  -27.567 21.039  1    47.725 ? 1795 HOH A H2     1 ? 
HETATM 6100 O O      . HOH D 4 .   ? 39.203  -26.421 19.33   1    30.372 ? 1796 HOH A O      1 ? 
HETATM 6101 H H1     . HOH D 4 .   ? 39.896  -25.99  19.868  1    30.612 ? 1796 HOH A H1     1 ? 
HETATM 6102 H H2     . HOH D 4 .   ? 38.358  -26.221 19.761  1    29.407 ? 1796 HOH A H2     1 ? 
HETATM 6103 O O      . HOH D 4 .   ? 30.828  -22.079 0.353   1    24.542 ? 1797 HOH A O      1 ? 
HETATM 6104 H H1     . HOH D 4 .   ? 30.807  -21.123 0.528   1    24.121 ? 1797 HOH A H1     1 ? 
HETATM 6105 H H2     . HOH D 4 .   ? 30.501  -22.567 1.145   1    24.351 ? 1797 HOH A H2     1 ? 
HETATM 6106 O O      . HOH D 4 .   ? 4.295   -15.567 33.346  1    46.823 ? 1798 HOH A O      1 ? 
HETATM 6107 H H1     . HOH D 4 .   ? 4.024   -15.713 32.413  1    41.727 ? 1798 HOH A H1     1 ? 
HETATM 6108 H H2     . HOH D 4 .   ? 5.267   -15.658 33.418  1    45.026 ? 1798 HOH A H2     1 ? 
HETATM 6109 O O      . HOH D 4 .   ? 6.929   -15.892 13.287  1    28.821 ? 1799 HOH A O      1 ? 
HETATM 6110 H H1     . HOH D 4 .   ? 6.677   -15.094 13.805  1    26.175 ? 1799 HOH A H1     1 ? 
HETATM 6111 H H2     . HOH D 4 .   ? 6.578   -16.675 13.759  1    27.993 ? 1799 HOH A H2     1 ? 
HETATM 6112 O O      . HOH D 4 .   ? 6.067   -4.731  26.763  1    52.274 ? 1800 HOH A O      1 ? 
HETATM 6113 H H1     . HOH D 4 .   ? 5.083   -4.694  26.791  1    48.69  ? 1800 HOH A H1     1 ? 
HETATM 6114 H H2     . HOH D 4 .   ? 6.353   -5.545  26.286  1    47.243 ? 1800 HOH A H2     1 ? 
HETATM 6115 O O      . HOH D 4 .   ? 1.362   -23.325 29.892  1    29.646 ? 1801 HOH A O      1 ? 
HETATM 6116 H H1     . HOH D 4 .   ? 0.664   -23.016 30.475  1    29.82  ? 1801 HOH A H1     1 ? 
HETATM 6117 H H2     . HOH D 4 .   ? 1       -23.237 28.995  1    32.418 ? 1801 HOH A H2     1 ? 
HETATM 6118 O O      . HOH D 4 .   ? 26.684  -22.606 35.015  1    34.221 ? 1802 HOH A O      1 ? 
HETATM 6119 H H1     . HOH D 4 .   ? 27.567  -22.377 35.355  1    32.378 ? 1802 HOH A H1     1 ? 
HETATM 6120 H H2     . HOH D 4 .   ? 26.785  -23.399 34.443  1    37.664 ? 1802 HOH A H2     1 ? 
HETATM 6121 O O      . HOH D 4 .   ? 25.173  -2.895  -7.293  1    26.675 ? 1803 HOH A O      1 ? 
HETATM 6122 H H1     . HOH D 4 .   ? 24.709  -2.95   -8.154  1    26.218 ? 1803 HOH A H1     1 ? 
HETATM 6123 H H2     . HOH D 4 .   ? 24.577  -2.429  -6.68   1    26.304 ? 1803 HOH A H2     1 ? 
HETATM 6124 O O      . HOH D 4 .   ? 25.387  -8.421  -12.543 1    33.462 ? 1804 HOH A O      1 ? 
HETATM 6125 H H1     . HOH D 4 .   ? 26.076  -8.845  -13.097 1    32.324 ? 1804 HOH A H1     1 ? 
HETATM 6126 H H2     . HOH D 4 .   ? 24.63   -8.198  -13.118 1    30.624 ? 1804 HOH A H2     1 ? 
HETATM 6127 O O      . HOH D 4 .   ? 29.654  -10.946 -5.69   1    37.592 ? 1805 HOH A O      1 ? 
HETATM 6128 H H1     . HOH D 4 .   ? 30.514  -10.486 -5.67   1    35.74  ? 1805 HOH A H1     1 ? 
HETATM 6129 H H2     . HOH D 4 .   ? 29.264  -10.803 -6.573  1    34.986 ? 1805 HOH A H2     1 ? 
HETATM 6130 O O      . HOH D 4 .   ? 7.034   -22.05  2.085   1    50.281 ? 1806 HOH A O      1 ? 
HETATM 6131 H H1     . HOH D 4 .   ? 6.077   -21.825 2.104   1    46.633 ? 1806 HOH A H1     1 ? 
HETATM 6132 H H2     . HOH D 4 .   ? 7.147   -22.943 1.7     1    48.581 ? 1806 HOH A H2     1 ? 
HETATM 6133 O O      . HOH D 4 .   ? 15.181  -5.598  -10.923 1    31.336 ? 1807 HOH A O      1 ? 
HETATM 6134 H H1     . HOH D 4 .   ? 15.67   -6.402  -11.195 1    28.978 ? 1807 HOH A H1     1 ? 
HETATM 6135 H H2     . HOH D 4 .   ? 15.534  -4.832  -11.418 1    30.163 ? 1807 HOH A H2     1 ? 
HETATM 6136 O O      . HOH D 4 .   ? 17.474  -31.796 7.361   1    39.053 ? 1808 HOH A O      1 ? 
HETATM 6137 H H1     . HOH D 4 .   ? 18.102  -32.434 7.737   1    38.522 ? 1808 HOH A H1     1 ? 
HETATM 6138 H H2     . HOH D 4 .   ? 16.846  -31.591 8.076   1    40.882 ? 1808 HOH A H2     1 ? 
HETATM 6139 O O      . HOH D 4 .   ? 0.992   -19.081 33.184  1    51.987 ? 1809 HOH A O      1 ? 
HETATM 6140 H H1     . HOH D 4 .   ? 1.734   -19.295 33.786  1    47.646 ? 1809 HOH A H1     1 ? 
HETATM 6141 H H2     . HOH D 4 .   ? 0.672   -18.17  33.373  1    49.405 ? 1809 HOH A H2     1 ? 
HETATM 6142 O O      . HOH D 4 .   ? 12.323  -1.423  -4.108  1    24.542 ? 1810 HOH A O      1 ? 
HETATM 6143 H H1     . HOH D 4 .   ? 13.137  -1.947  -4.073  1    24.205 ? 1810 HOH A H1     1 ? 
HETATM 6144 H H2     . HOH D 4 .   ? 12.592  -0.57   -4.506  1    24.545 ? 1810 HOH A H2     1 ? 
HETATM 6145 O O      . HOH D 4 .   ? -1.547  -18.347 16.244  1    46.043 ? 1811 HOH A O      1 ? 
HETATM 6146 H H1     . HOH D 4 .   ? -1.16   -19.213 16.017  1    46.253 ? 1811 HOH A H1     1 ? 
HETATM 6147 H H2     . HOH D 4 .   ? -1.134  -17.682 15.664  1    43.92  ? 1811 HOH A H2     1 ? 
HETATM 6148 O O      . HOH D 4 .   ? -11.016 -14.297 26.844  1    50.448 ? 1812 HOH A O      1 ? 
HETATM 6149 H H1     . HOH D 4 .   ? -10.374 -13.622 26.549  1    49.312 ? 1812 HOH A H1     1 ? 
HETATM 6150 H H2     . HOH D 4 .   ? -11.86  -14.127 26.385  1    46.673 ? 1812 HOH A H2     1 ? 
HETATM 6151 O O      . HOH D 4 .   ? 30.621  -15.526 -2.156  1    18.764 ? 1813 HOH A O      1 ? 
HETATM 6152 H H1     . HOH D 4 .   ? 31.125  -14.934 -1.567  1    19.062 ? 1813 HOH A H1     1 ? 
HETATM 6153 H H2     . HOH D 4 .   ? 30.119  -14.92  -2.737  1    19.693 ? 1813 HOH A H2     1 ? 
HETATM 6154 O O      . HOH D 4 .   ? 26.821  -13.728 30.485  1    55.262 ? 1814 HOH A O      1 ? 
HETATM 6155 H H1     . HOH D 4 .   ? 27.011  -14.595 30.905  1    49.294 ? 1814 HOH A H1     1 ? 
HETATM 6156 H H2     . HOH D 4 .   ? 25.884  -13.704 30.197  1    53.703 ? 1814 HOH A H2     1 ? 
HETATM 6157 O O      . HOH D 4 .   ? 13.88   -14.829 34.167  1    23.932 ? 1815 HOH A O      1 ? 
HETATM 6158 H H1     . HOH D 4 .   ? 14.408  -14.022 34.288  1    23.011 ? 1815 HOH A H1     1 ? 
HETATM 6159 H H2     . HOH D 4 .   ? 13.082  -14.566 33.711  1    22.163 ? 1815 HOH A H2     1 ? 
HETATM 6160 O O      . HOH D 4 .   ? -2.163  -33.556 19.19   1    45.071 ? 1816 HOH A O      1 ? 
HETATM 6161 H H1     . HOH D 4 .   ? -1.756  -34.367 19.555  1    41.58  ? 1816 HOH A H1     1 ? 
HETATM 6162 H H2     . HOH D 4 .   ? -2.54   -33.032 19.929  1    44.376 ? 1816 HOH A H2     1 ? 
HETATM 6163 O O      . HOH D 4 .   ? 3.178   -33.788 15.588  1    37.037 ? 1817 HOH A O      1 ? 
HETATM 6164 H H1     . HOH D 4 .   ? 3.898   -34.121 16.159  1    35.752 ? 1817 HOH A H1     1 ? 
HETATM 6165 H H2     . HOH D 4 .   ? 3.586   -33.317 14.836  1    35.799 ? 1817 HOH A H2     1 ? 
HETATM 6166 O O      . HOH D 4 .   ? 4.9     -20.131 15.344  1    30.184 ? 1818 HOH A O      1 ? 
HETATM 6167 H H1     . HOH D 4 .   ? 4.654   -20     16.276  1    28.418 ? 1818 HOH A H1     1 ? 
HETATM 6168 H H2     . HOH D 4 .   ? 4.143   -20.538 14.912  1    27.484 ? 1818 HOH A H2     1 ? 
HETATM 6169 O O      . HOH D 4 .   ? 28.035  -27.463 8.347   1    30.897 ? 1819 HOH A O      1 ? 
HETATM 6170 H H1     . HOH D 4 .   ? 28.492  -27.814 7.56    1    29.097 ? 1819 HOH A H1     1 ? 
HETATM 6171 H H2     . HOH D 4 .   ? 28.68   -27.002 8.929   1    29.135 ? 1819 HOH A H2     1 ? 
HETATM 6172 O O      . HOH D 4 .   ? 33.118  -36.658 15.511  1    41.748 ? 1820 HOH A O      1 ? 
HETATM 6173 H H1     . HOH D 4 .   ? 32.32   -36.421 14.993  1    42.028 ? 1820 HOH A H1     1 ? 
HETATM 6174 H H2     . HOH D 4 .   ? 32.964  -37.571 15.816  1    38.722 ? 1820 HOH A H2     1 ? 
HETATM 6175 O O      . HOH D 4 .   ? 11.34   -26.203 5.07    1    39.579 ? 1821 HOH A O      1 ? 
HETATM 6176 H H1     . HOH D 4 .   ? 11.319  -25.961 4.123   1    41.411 ? 1821 HOH A H1     1 ? 
HETATM 6177 H H2     . HOH D 4 .   ? 10.761  -25.574 5.545   1    36.373 ? 1821 HOH A H2     1 ? 
HETATM 6178 O O      . HOH D 4 .   ? 21.744  -6.735  22.788  1    37.67  ? 1822 HOH A O      1 ? 
HETATM 6179 H H1     . HOH D 4 .   ? 21.167  -6.381  23.484  1    35.974 ? 1822 HOH A H1     1 ? 
HETATM 6180 H H2     . HOH D 4 .   ? 22.017  -7.622  23.075  1    36.672 ? 1822 HOH A H2     1 ? 
HETATM 6181 O O      . HOH D 4 .   ? 13.13   -13.813 -19.032 1    39.948 ? 1823 HOH A O      1 ? 
HETATM 6182 H H1     . HOH D 4 .   ? 13.318  -12.857 -18.934 1    37.526 ? 1823 HOH A H1     1 ? 
HETATM 6183 H H2     . HOH D 4 .   ? 13.287  -14.06  -19.966 1    38.932 ? 1823 HOH A H2     1 ? 
HETATM 6184 O O      . HOH D 4 .   ? 25.756  -0.531  3.740   1    38.19  ? 1824 HOH A O      1 ? 
HETATM 6185 H H1     . HOH D 4 .   ? 25.355  0.318   3.478   1    36.232 ? 1824 HOH A H1     1 ? 
HETATM 6186 H H2     . HOH D 4 .   ? 26.352  -0.810  3.014   1    33.874 ? 1824 HOH A H2     1 ? 
HETATM 6187 O O      . HOH D 4 .   ? 16.743  -26.233 -1.481  1    41.064 ? 1825 HOH A O      1 ? 
HETATM 6188 H H1     . HOH D 4 .   ? 17.663  -26.433 -1.746  1    37.946 ? 1825 HOH A H1     1 ? 
HETATM 6189 H H2     . HOH D 4 .   ? 16.76   -25.464 -0.881  1    38.927 ? 1825 HOH A H2     1 ? 
HETATM 6190 O O      . HOH D 4 .   ? 27.607  -19.3   -8.231  1    33.66  ? 1826 HOH A O      1 ? 
HETATM 6191 H H1     . HOH D 4 .   ? 28.563  -19.551 -8.14   1    30.985 ? 1826 HOH A H1     1 ? 
HETATM 6192 H H2     . HOH D 4 .   ? 27.538  -18.345 -8.456  1    33.673 ? 1826 HOH A H2     1 ? 
HETATM 6193 O O      . HOH D 4 .   ? 6.667   -11.177 12.392  1    25.8   ? 1827 HOH A O      1 ? 
HETATM 6194 H H1     . HOH D 4 .   ? 6.339   -12.049 12.696  1    24.618 ? 1827 HOH A H1     1 ? 
HETATM 6195 H H2     . HOH D 4 .   ? 6.649   -11.155 11.416  1    25.15  ? 1827 HOH A H2     1 ? 
HETATM 6196 O O      . HOH D 4 .   ? 22.055  -0.031  8.2     1    34.025 ? 1828 HOH A O      1 ? 
HETATM 6197 H H1     . HOH D 4 .   ? 22.489  -0.698  8.756   1    33.914 ? 1828 HOH A H1     1 ? 
HETATM 6198 H H2     . HOH D 4 .   ? 21.11   -0.024  8.436   1    35.209 ? 1828 HOH A H2     1 ? 
HETATM 6199 O O      . HOH D 4 .   ? 1.081   -21.919 15.527  1    38.982 ? 1829 HOH A O      1 ? 
HETATM 6200 H H1     . HOH D 4 .   ? 0.907   -22.714 14.997  1    36.488 ? 1829 HOH A H1     1 ? 
HETATM 6201 H H2     . HOH D 4 .   ? 0.271   -21.375 15.503  1    38.876 ? 1829 HOH A H2     1 ? 
HETATM 6202 O O      . HOH D 4 .   ? 0.095   -13.489 22.974  1    32.608 ? 1830 HOH A O      1 ? 
HETATM 6203 H H1     . HOH D 4 .   ? 0.417   -12.662 23.422  1    29.57  ? 1830 HOH A H1     1 ? 
HETATM 6204 H H2     . HOH D 4 .   ? 0.15    -13.414 21.983  1    28.994 ? 1830 HOH A H2     1 ? 
HETATM 6205 O O      . HOH D 4 .   ? 23.004  -18.529 32.354  1    42.8   ? 1831 HOH A O      1 ? 
HETATM 6206 H H1     . HOH D 4 .   ? 22.969  -19.479 32.612  1    42.557 ? 1831 HOH A H1     1 ? 
HETATM 6207 H H2     . HOH D 4 .   ? 23.547  -18.435 31.542  1    43.215 ? 1831 HOH A H2     1 ? 
HETATM 6208 O O      . HOH D 4 .   ? 10.391  -17.142 -13.835 1    25.546 ? 1832 HOH A O      1 ? 
HETATM 6209 H H1     . HOH D 4 .   ? 10.868  -17.586 -14.563 1    24.982 ? 1832 HOH A H1     1 ? 
HETATM 6210 H H2     . HOH D 4 .   ? 10.208  -17.816 -13.162 1    25.647 ? 1832 HOH A H2     1 ? 
HETATM 6211 O O      . HOH D 4 .   ? 22.093  -18.33  -11.999 1    30.331 ? 1833 HOH A O      1 ? 
HETATM 6212 H H1     . HOH D 4 .   ? 22.083  -17.757 -12.809 1    28.172 ? 1833 HOH A H1     1 ? 
HETATM 6213 H H2     . HOH D 4 .   ? 23.017  -18.527 -11.764 1    29.888 ? 1833 HOH A H2     1 ? 
HETATM 6214 O O      . HOH D 4 .   ? -0.422  -39.061 17.499  1    41.268 ? 1834 HOH A O      1 ? 
HETATM 6215 H H1     . HOH D 4 .   ? 0.207   -38.317 17.534  1    40.276 ? 1834 HOH A H1     1 ? 
HETATM 6216 H H2     . HOH D 4 .   ? -1.319  -38.687 17.516  1    40.82  ? 1834 HOH A H2     1 ? 
HETATM 6217 O O      . HOH D 4 .   ? 39.356  -28.607 17.522  1    48.795 ? 1835 HOH A O      1 ? 
HETATM 6218 H H1     . HOH D 4 .   ? 39.584  -29.315 18.155  1    45.355 ? 1835 HOH A H1     1 ? 
HETATM 6219 H H2     . HOH D 4 .   ? 39.304  -27.771 18.023  1    46.102 ? 1835 HOH A H2     1 ? 
HETATM 6220 O O      . HOH D 4 .   ? 6.005   -16.763 -7.842  1    28.315 ? 1836 HOH A O      1 ? 
HETATM 6221 H H1     . HOH D 4 .   ? 5.565   -17.524 -8.261  1    29.217 ? 1836 HOH A H1     1 ? 
HETATM 6222 H H2     . HOH D 4 .   ? 5.79    -16.797 -6.893  1    28.302 ? 1836 HOH A H2     1 ? 
HETATM 6223 O O      . HOH D 4 .   ? 7.9     -12.939 30.156  1    38.451 ? 1837 HOH A O      1 ? 
HETATM 6224 H H1     . HOH D 4 .   ? 8.544   -13.096 30.868  1    38.711 ? 1837 HOH A H1     1 ? 
HETATM 6225 H H2     . HOH D 4 .   ? 7.485   -12.074 30.324  1    39.063 ? 1837 HOH A H2     1 ? 
HETATM 6226 O O      . HOH D 4 .   ? 26.129  -35.633 23.882  1    30.696 ? 1838 HOH A O      1 ? 
HETATM 6227 H H1     . HOH D 4 .   ? 26.647  -35.31  24.651  1    28.981 ? 1838 HOH A H1     1 ? 
HETATM 6228 H H2     . HOH D 4 .   ? 26.721  -35.655 23.109  1    29.168 ? 1838 HOH A H2     1 ? 
HETATM 6229 O O      . HOH D 4 .   ? 22.713  -40.588 18.682  1    30.428 ? 1839 HOH A O      1 ? 
HETATM 6230 H H1     . HOH D 4 .   ? 23.141  -39.866 19.181  1    29.6   ? 1839 HOH A H1     1 ? 
HETATM 6231 H H2     . HOH D 4 .   ? 22.171  -40.185 17.979  1    29.324 ? 1839 HOH A H2     1 ? 
HETATM 6232 O O      . HOH D 4 .   ? 29.846  -12.908 -10.346 1    38.347 ? 1840 HOH A O      1 ? 
HETATM 6233 H H1     . HOH D 4 .   ? 30.636  -13.456 -10.181 1    37.922 ? 1840 HOH A H1     1 ? 
HETATM 6234 H H2     . HOH D 4 .   ? 29.587  -12.514 -9.491  1    39.825 ? 1840 HOH A H2     1 ? 
HETATM 6235 O O      . HOH D 4 .   ? 7.497   -28.583 0.139   1    44.243 ? 1841 HOH A O      1 ? 
HETATM 6236 H H1     . HOH D 4 .   ? 6.998   -27.819 -0.197  1    39.112 ? 1841 HOH A H1     1 ? 
HETATM 6237 H H2     . HOH D 4 .   ? 7.672   -28.421 1.082   1    40.341 ? 1841 HOH A H2     1 ? 
HETATM 6238 O O      . HOH D 4 .   ? 18.512  -40.957 27.251  1    32.004 ? 1842 HOH A O      1 ? 
HETATM 6239 H H1     . HOH D 4 .   ? 18.317  -40.798 28.2    1    29.267 ? 1842 HOH A H1     1 ? 
HETATM 6240 H H2     . HOH D 4 .   ? 19.464  -41.185 27.17   1    29.026 ? 1842 HOH A H2     1 ? 
HETATM 6241 O O      . HOH D 4 .   ? 3.624   -22.278 13.889  1    34.528 ? 1843 HOH A O      1 ? 
HETATM 6242 H H1     . HOH D 4 .   ? 2.747   -21.965 14.208  1    29.436 ? 1843 HOH A H1     1 ? 
HETATM 6243 H H2     . HOH D 4 .   ? 3.511   -23.073 13.317  1    31.455 ? 1843 HOH A H2     1 ? 
HETATM 6244 O O      . HOH D 4 .   ? 8.204   -17.834 -8.819  1    38.35  ? 1844 HOH A O      1 ? 
HETATM 6245 H H1     . HOH D 4 .   ? 7.928   -17.031 -8.333  1    36.194 ? 1844 HOH A H1     1 ? 
HETATM 6246 H H2     . HOH D 4 .   ? 7.399   -18.23  -9.197  1    37.495 ? 1844 HOH A H2     1 ? 
HETATM 6247 O O      . HOH D 4 .   ? 20.814  1.783   4.791   1    36.685 ? 1845 HOH A O      1 ? 
HETATM 6248 H H1     . HOH D 4 .   ? 21.597  1.351   4.395   1    34.992 ? 1845 HOH A H1     1 ? 
HETATM 6249 H H2     . HOH D 4 .   ? 21.035  2.016   5.712   1    36.868 ? 1845 HOH A H2     1 ? 
HETATM 6250 O O      . HOH D 4 .   ? -6.710  -14.306 29.859  1    53.319 ? 1846 HOH A O      1 ? 
HETATM 6251 H H1     . HOH D 4 .   ? -6.570  -13.522 29.295  1    55.612 ? 1846 HOH A H1     1 ? 
HETATM 6252 H H2     . HOH D 4 .   ? -7.470  -14.792 29.490  1    51.899 ? 1846 HOH A H2     1 ? 
HETATM 6253 O O      . HOH D 4 .   ? 7.866   -36.948 28.144  1    32.917 ? 1847 HOH A O      1 ? 
HETATM 6254 H H1     . HOH D 4 .   ? 7.318   -36.146 28.196  1    31.4   ? 1847 HOH A H1     1 ? 
HETATM 6255 H H2     . HOH D 4 .   ? 7.358   -37.597 27.636  1    30.056 ? 1847 HOH A H2     1 ? 
HETATM 6256 O O      . HOH D 4 .   ? 21.744  -27.277 0.576   1    27.66  ? 1848 HOH A O      1 ? 
HETATM 6257 H H1     . HOH D 4 .   ? 22.523  -27.049 1.095   1    29.397 ? 1848 HOH A H1     1 ? 
HETATM 6258 H H2     . HOH D 4 .   ? 21.751  -28.246 0.486   1    27.682 ? 1848 HOH A H2     1 ? 
HETATM 6259 O O      . HOH D 4 .   ? 32.935  -10.91  0.793   1    52.539 ? 1849 HOH A O      1 ? 
HETATM 6260 H H1     . HOH D 4 .   ? 33.817  -11.296 1.003   1    45.454 ? 1849 HOH A H1     1 ? 
HETATM 6261 H H2     . HOH D 4 .   ? 33.026  -9.937  0.673   1    51.081 ? 1849 HOH A H2     1 ? 
HETATM 6262 O O      . HOH D 4 .   ? 18.732  -29.175 -7.693  1    34.579 ? 1850 HOH A O      1 ? 
HETATM 6263 H H1     . HOH D 4 .   ? 19.062  -29.22  -6.771  1    32.927 ? 1850 HOH A H1     1 ? 
HETATM 6264 H H2     . HOH D 4 .   ? 19.497  -29.032 -8.272  1    34.674 ? 1850 HOH A H2     1 ? 
HETATM 6265 O O      . HOH D 4 .   ? -17.638 -16.561 25.900  1    43.474 ? 1851 HOH A O      1 ? 
HETATM 6266 H H1     . HOH D 4 .   ? -17.742 -15.671 26.303  1    39.706 ? 1851 HOH A H1     1 ? 
HETATM 6267 H H2     . HOH D 4 .   ? -18.441 -17.098 26.074  1    37.322 ? 1851 HOH A H2     1 ? 
HETATM 6268 O O      . HOH D 4 .   ? 27.317  -37.331 16.005  1    46.018 ? 1852 HOH A O      1 ? 
HETATM 6269 H H1     . HOH D 4 .   ? 27.682  -37.594 16.867  1    45.969 ? 1852 HOH A H1     1 ? 
HETATM 6270 H H2     . HOH D 4 .   ? 26.438  -36.948 16.173  1    45.487 ? 1852 HOH A H2     1 ? 
HETATM 6271 O O      . HOH D 4 .   ? 12.937  -3.255  19.897  1    45.517 ? 1853 HOH A O      1 ? 
HETATM 6272 H H1     . HOH D 4 .   ? 13.855  -3.135  20.207  1    42.903 ? 1853 HOH A H1     1 ? 
HETATM 6273 H H2     . HOH D 4 .   ? 12.688  -2.452  19.399  1    46.327 ? 1853 HOH A H2     1 ? 
HETATM 6274 O O      . HOH D 4 .   ? 23.217  2.035   13.726  1    81.372 ? 1854 HOH A O      1 ? 
HETATM 6275 H H1     . HOH D 4 .   ? 24.187  1.915   13.755  1    79.354 ? 1854 HOH A H1     1 ? 
HETATM 6276 H H2     . HOH D 4 .   ? 23.009  2.837   13.208  1    75.495 ? 1854 HOH A H2     1 ? 
HETATM 6277 O O      . HOH D 4 .   ? 35.529  -35.254 18.532  1    42.643 ? 1855 HOH A O      1 ? 
HETATM 6278 H H1     . HOH D 4 .   ? 34.936  -34.823 19.175  1    40.756 ? 1855 HOH A H1     1 ? 
HETATM 6279 H H2     . HOH D 4 .   ? 36.282  -35.638 19.019  1    40.239 ? 1855 HOH A H2     1 ? 
HETATM 6280 O O      . HOH D 4 .   ? 17.707  0.372   9.9     1    31.68  ? 1856 HOH A O      1 ? 
HETATM 6281 H H1     . HOH D 4 .   ? 18.44   0.862   9.492   1    31.523 ? 1856 HOH A H1     1 ? 
HETATM 6282 H H2     . HOH D 4 .   ? 17.408  -0.283  9.242   1    33.266 ? 1856 HOH A H2     1 ? 
HETATM 6283 O O      . HOH D 4 .   ? 16.123  -14.536 35.166  1    39.883 ? 1857 HOH A O      1 ? 
HETATM 6284 H H1     . HOH D 4 .   ? 16.421  -15.406 35.49   1    38.865 ? 1857 HOH A H1     1 ? 
HETATM 6285 H H2     . HOH D 4 .   ? 15.414  -14.226 35.765  1    35.293 ? 1857 HOH A H2     1 ? 
HETATM 6286 O O      . HOH D 4 .   ? 15.765  1.725   10.948  1    45.741 ? 1858 HOH A O      1 ? 
HETATM 6287 H H1     . HOH D 4 .   ? 16.678  1.747   11.316  1    41.35  ? 1858 HOH A H1     1 ? 
HETATM 6288 H H2     . HOH D 4 .   ? 15.145  1.33    11.603  1    38.284 ? 1858 HOH A H2     1 ? 
HETATM 6289 O O      . HOH D 4 .   ? 39.62   -7.454  19.159  1    72.477 ? 1859 HOH A O      1 ? 
HETATM 6290 H H1     . HOH D 4 .   ? 40.023  -7.389  20.043  1    69.949 ? 1859 HOH A H1     1 ? 
HETATM 6291 H H2     . HOH D 4 .   ? 38.733  -7.05   19.22   1    68.997 ? 1859 HOH A H2     1 ? 
HETATM 6292 O O      . HOH D 4 .   ? 5.071   -21.161 -0.335  1    42.084 ? 1860 HOH A O      1 ? 
HETATM 6293 H H1     . HOH D 4 .   ? 5.243   -22.108 -0.242  1    41.697 ? 1860 HOH A H1     1 ? 
HETATM 6294 H H2     . HOH D 4 .   ? 4.291   -20.958 0.209   1    42.4   ? 1860 HOH A H2     1 ? 
HETATM 6295 O O      . HOH D 4 .   ? 32.042  -26.961 30.305  1    18.126 ? 1861 HOH A O      1 ? 
HETATM 6296 H H1     . HOH D 4 .   ? 32.703  -27.686 30.377  1    18.894 ? 1861 HOH A H1     1 ? 
HETATM 6297 H H2     . HOH D 4 .   ? 31.212  -27.313 30.655  1    20.001 ? 1861 HOH A H2     1 ? 
HETATM 6298 O O      . HOH D 4 .   ? 24.142  -26.889 4.453   1    31.823 ? 1862 HOH A O      1 ? 
HETATM 6299 H H1     . HOH D 4 .   ? 24.957  -26.838 4.979   1    30.526 ? 1862 HOH A H1     1 ? 
HETATM 6300 H H2     . HOH D 4 .   ? 24.079  -26.061 3.925   1    31.982 ? 1862 HOH A H2     1 ? 
HETATM 6301 O O      . HOH D 4 .   ? -16.657 -22.363 20.959  1    42.253 ? 1863 HOH A O      1 ? 
HETATM 6302 H H1     . HOH D 4 .   ? -15.814 -22.399 21.447  1    46.192 ? 1863 HOH A H1     1 ? 
HETATM 6303 H H2     . HOH D 4 .   ? -16.978 -21.444 20.993  1    41.821 ? 1863 HOH A H2     1 ? 
HETATM 6304 O O      . HOH D 4 .   ? 3.971   -29.277 15.789  1    21.123 ? 1864 HOH A O      1 ? 
HETATM 6305 H H1     . HOH D 4 .   ? 4.803   -29.709 15.528  1    20.84  ? 1864 HOH A H1     1 ? 
HETATM 6306 H H2     . HOH D 4 .   ? 4.119   -28.323 15.648  1    21.036 ? 1864 HOH A H2     1 ? 
HETATM 6307 O O      . HOH D 4 .   ? 38.753  -21.645 8.263   1    36.363 ? 1865 HOH A O      1 ? 
HETATM 6308 H H1     . HOH D 4 .   ? 38.716  -22.615 8.304   1    36.466 ? 1865 HOH A H1     1 ? 
HETATM 6309 H H2     . HOH D 4 .   ? 37.96   -21.328 8.739   1    32.471 ? 1865 HOH A H2     1 ? 
HETATM 6310 O O      . HOH D 4 .   ? 24.14   -39.297 20.593  1    46.123 ? 1866 HOH A O      1 ? 
HETATM 6311 H H1     . HOH D 4 .   ? 23.91   -40.181 20.934  1    45.164 ? 1866 HOH A H1     1 ? 
HETATM 6312 H H2     . HOH D 4 .   ? 25.016  -39.032 20.957  1    42.829 ? 1866 HOH A H2     1 ? 
HETATM 6313 O O      . HOH D 4 .   ? 41.948  -23.621 16.181  1    55.442 ? 1867 HOH A O      1 ? 
HETATM 6314 H H1     . HOH D 4 .   ? 42.062  -22.828 15.605  1    51.915 ? 1867 HOH A H1     1 ? 
HETATM 6315 H H2     . HOH D 4 .   ? 41.312  -23.44  16.908  1    50.056 ? 1867 HOH A H2     1 ? 
HETATM 6316 O O      . HOH D 4 .   ? 18.429  -38.311 30.766  1    29.806 ? 1868 HOH A O      1 ? 
HETATM 6317 H H1     . HOH D 4 .   ? 19.35   -38.069 30.5    1    27.379 ? 1868 HOH A H1     1 ? 
HETATM 6318 H H2     . HOH D 4 .   ? 17.94   -37.496 31.016  1    28.331 ? 1868 HOH A H2     1 ? 
HETATM 6319 O O      . HOH D 4 .   ? 35.416  -27.189 6.411   1    59.674 ? 1869 HOH A O      1 ? 
HETATM 6320 H H1     . HOH D 4 .   ? 36.178  -26.596 6.523   1    57.519 ? 1869 HOH A H1     1 ? 
HETATM 6321 H H2     . HOH D 4 .   ? 34.939  -27.205 7.261   1    57.276 ? 1869 HOH A H2     1 ? 
HETATM 6322 O O      . HOH D 4 .   ? -2.007  -3.479  18.921  1    45.615 ? 1870 HOH A O      1 ? 
HETATM 6323 H H1     . HOH D 4 .   ? -1.115  -3.239  18.594  1    44.347 ? 1870 HOH A H1     1 ? 
HETATM 6324 H H2     . HOH D 4 .   ? -1.913  -4.074  19.693  1    40.22  ? 1870 HOH A H2     1 ? 
HETATM 6325 O O      . HOH D 4 .   ? 26.279  -35.127 21.539  1    36.04  ? 1871 HOH A O      1 ? 
HETATM 6326 H H1     . HOH D 4 .   ? 25.897  -35.233 20.657  1    38.147 ? 1871 HOH A H1     1 ? 
HETATM 6327 H H2     . HOH D 4 .   ? 25.556  -34.808 22.103  1    35.872 ? 1871 HOH A H2     1 ? 
HETATM 6328 O O      . HOH D 4 .   ? 10.985  -24.367 40.987  1    24.369 ? 1872 HOH A O      1 ? 
HETATM 6329 H H1     . HOH D 4 .   ? 10.879  -23.811 40.201  1    24.56  ? 1872 HOH A H1     1 ? 
HETATM 6330 H H2     . HOH D 4 .   ? 10.931  -23.757 41.735  1    23.407 ? 1872 HOH A H2     1 ? 
HETATM 6331 O O      . HOH D 4 .   ? -8.085  -21.441 12.915  1    42.038 ? 1873 HOH A O      1 ? 
HETATM 6332 H H1     . HOH D 4 .   ? -7.38   -20.818 13.166  1    41.094 ? 1873 HOH A H1     1 ? 
HETATM 6333 H H2     . HOH D 4 .   ? -8.555  -21.684 13.734  1    41.317 ? 1873 HOH A H2     1 ? 
HETATM 6334 O O      . HOH D 4 .   ? 14.633  -7.296  24.202  1    31.609 ? 1874 HOH A O      1 ? 
HETATM 6335 H H1     . HOH D 4 .   ? 15.228  -7.883  23.708  1    30.231 ? 1874 HOH A H1     1 ? 
HETATM 6336 H H2     . HOH D 4 .   ? 14.954  -6.378  24.071  1    30.632 ? 1874 HOH A H2     1 ? 
HETATM 6337 O O      . HOH D 4 .   ? 18.961  -28.086 -12.174 1    29.701 ? 1875 HOH A O      1 ? 
HETATM 6338 H H1     . HOH D 4 .   ? 19.608  -27.421 -12.49  1    27.799 ? 1875 HOH A H1     1 ? 
HETATM 6339 H H2     . HOH D 4 .   ? 19.28   -28.458 -11.322 1    28.061 ? 1875 HOH A H2     1 ? 
HETATM 6340 O O      . HOH D 4 .   ? 22.741  1.413   0.689   1    35.805 ? 1876 HOH A O      1 ? 
HETATM 6341 H H1     . HOH D 4 .   ? 22.036  1.099   0.090   1    34.907 ? 1876 HOH A H1     1 ? 
HETATM 6342 H H2     . HOH D 4 .   ? 23.589  1.115   0.310   1    34.687 ? 1876 HOH A H2     1 ? 
HETATM 6343 O O      . HOH D 4 .   ? 21.684  -30.346 3.866   1    44.548 ? 1877 HOH A O      1 ? 
HETATM 6344 H H1     . HOH D 4 .   ? 21.556  -30.824 3.025   1    44.699 ? 1877 HOH A H1     1 ? 
HETATM 6345 H H2     . HOH D 4 .   ? 22.642  -30.3   4.044   1    42.741 ? 1877 HOH A H2     1 ? 
HETATM 6346 O O      . HOH D 4 .   ? 6.396   -11.327 5.114   1    37.623 ? 1878 HOH A O      1 ? 
HETATM 6347 H H1     . HOH D 4 .   ? 5.656   -11.24  5.751   1    38.355 ? 1878 HOH A H1     1 ? 
HETATM 6348 H H2     . HOH D 4 .   ? 6.394   -12.237 4.778   1    35.699 ? 1878 HOH A H2     1 ? 
HETATM 6349 O O      . HOH D 4 .   ? 1.089   -27.463 29.271  1    27.593 ? 1879 HOH A O      1 ? 
HETATM 6350 H H1     . HOH D 4 .   ? 0.607   -27.704 28.455  1    28.478 ? 1879 HOH A H1     1 ? 
HETATM 6351 H H2     . HOH D 4 .   ? 1.348   -26.521 29.207  1    28.127 ? 1879 HOH A H2     1 ? 
HETATM 6352 O O      . HOH D 4 .   ? 23.759  -31.673 5.715   1    39.045 ? 1880 HOH A O      1 ? 
HETATM 6353 H H1     . HOH D 4 .   ? 24.401  -32.375 5.479   1    37.992 ? 1880 HOH A H1     1 ? 
HETATM 6354 H H2     . HOH D 4 .   ? 24.197  -30.808 5.598   1    37.57  ? 1880 HOH A H2     1 ? 
HETATM 6355 O O      . HOH D 4 .   ? 8.495   -31.894 33.937  1    31.692 ? 1881 HOH A O      1 ? 
HETATM 6356 H H1     . HOH D 4 .   ? 9.060   -32.451 34.510  1    30.584 ? 1881 HOH A H1     1 ? 
HETATM 6357 H H2     . HOH D 4 .   ? 7.708   -32.422 33.703  1    29.999 ? 1881 HOH A H2     1 ? 
HETATM 6358 O O      . HOH D 4 .   ? 30.506  -29.624 8.061   1    50.667 ? 1882 HOH A O      1 ? 
HETATM 6359 H H1     . HOH D 4 .   ? 29.595  -29.99  8.112   1    48.784 ? 1882 HOH A H1     1 ? 
HETATM 6360 H H2     . HOH D 4 .   ? 31.06   -30.042 8.756   1    47.381 ? 1882 HOH A H2     1 ? 
HETATM 6361 O O      . HOH D 4 .   ? 38.315  -9.947  8.363   1    40.867 ? 1883 HOH A O      1 ? 
HETATM 6362 H H1     . HOH D 4 .   ? 37.807  -9.199  8.001   1    38.36  ? 1883 HOH A H1     1 ? 
HETATM 6363 H H2     . HOH D 4 .   ? 37.858  -10.255 9.172   1    41.312 ? 1883 HOH A H2     1 ? 
HETATM 6364 O O      . HOH D 4 .   ? 24.565  -27.217 1.825   1    34.778 ? 1884 HOH A O      1 ? 
HETATM 6365 H H1     . HOH D 4 .   ? 24.557  -26.25  1.855   1    32.941 ? 1884 HOH A H1     1 ? 
HETATM 6366 H H2     . HOH D 4 .   ? 23.834  -27.494 2.395   1    34.085 ? 1884 HOH A H2     1 ? 
HETATM 6367 O O      . HOH D 4 .   ? 19.204  -15.344 35.002  1    48.032 ? 1885 HOH A O      1 ? 
HETATM 6368 H H1     . HOH D 4 .   ? 19.521  -15.248 34.083  1    44.461 ? 1885 HOH A H1     1 ? 
HETATM 6369 H H2     . HOH D 4 .   ? 18.447  -14.737 35.118  1    47.943 ? 1885 HOH A H2     1 ? 
HETATM 6370 O O      . HOH D 4 .   ? -1.17   -28.325 14.369  1    44.158 ? 1886 HOH A O      1 ? 
HETATM 6371 H H1     . HOH D 4 .   ? -1.698  -29.07  14.035  1    44.184 ? 1886 HOH A H1     1 ? 
HETATM 6372 H H2     . HOH D 4 .   ? -1.274  -27.579 13.742  1    41.685 ? 1886 HOH A H2     1 ? 
HETATM 6373 O O      . HOH D 4 .   ? 2.715   -21.410 -3.183  1    39.472 ? 1887 HOH A O      1 ? 
HETATM 6374 H H1     . HOH D 4 .   ? 3.500   -21.068 -3.648  1    36.727 ? 1887 HOH A H1     1 ? 
HETATM 6375 H H2     . HOH D 4 .   ? 2.857   -21.342 -2.212  1    38.01  ? 1887 HOH A H2     1 ? 
HETATM 6376 O O      . HOH D 4 .   ? 6.133   -13.661 14.144  1    40.46  ? 1888 HOH A O      1 ? 
HETATM 6377 H H1     . HOH D 4 .   ? 6.685   -13.436 14.921  1    37.261 ? 1888 HOH A H1     1 ? 
HETATM 6378 H H2     . HOH D 4 .   ? 5.312   -13.135 14.192  1    40.849 ? 1888 HOH A H2     1 ? 
HETATM 6379 O O      . HOH D 4 .   ? 23.011  -20.909 33.762  1    32.388 ? 1889 HOH A O      1 ? 
HETATM 6380 H H1     . HOH D 4 .   ? 22.526  -20.811 34.617  1    31.264 ? 1889 HOH A H1     1 ? 
HETATM 6381 H H2     . HOH D 4 .   ? 23.187  -21.87  33.624  1    30.415 ? 1889 HOH A H2     1 ? 
HETATM 6382 O O      . HOH D 4 .   ? 21.815  0.739   -4.360  1    48.512 ? 1890 HOH A O      1 ? 
HETATM 6383 H H1     . HOH D 4 .   ? 21.796  1.256   -3.518  1    47.785 ? 1890 HOH A H1     1 ? 
HETATM 6384 H H2     . HOH D 4 .   ? 22.253  1.273   -5.064  1    40.686 ? 1890 HOH A H2     1 ? 
HETATM 6385 O O      . HOH D 4 .   ? 31.05   -11.62  -3.516  1    19.247 ? 1891 HOH A O      1 ? 
HETATM 6386 H H1     . HOH D 4 .   ? 31.15   -11.588 -2.548  1    18.863 ? 1891 HOH A H1     1 ? 
HETATM 6387 H H2     . HOH D 4 .   ? 30.912  -10.696 -3.799  1    19.689 ? 1891 HOH A H2     1 ? 
HETATM 6388 O O      . HOH D 4 .   ? 4.696   -14.077 9.268   1    38.778 ? 1892 HOH A O      1 ? 
HETATM 6389 H H1     . HOH D 4 .   ? 5.662   -14.216 9.233   1    39.326 ? 1892 HOH A H1     1 ? 
HETATM 6390 H H2     . HOH D 4 .   ? 4.538   -13.121 9.181   1    38.882 ? 1892 HOH A H2     1 ? 
HETATM 6391 O O      . HOH D 4 .   ? 31.751  -20.077 -3.273  1    31.071 ? 1893 HOH A O      1 ? 
HETATM 6392 H H1     . HOH D 4 .   ? 31.543  -20.322 -2.35   1    29.05  ? 1893 HOH A H1     1 ? 
HETATM 6393 H H2     . HOH D 4 .   ? 31.973  -19.114 -3.326  1    29.91  ? 1893 HOH A H2     1 ? 
HETATM 6394 O O      . HOH D 4 .   ? 27.714  -11.190 -13.891 1    41.153 ? 1894 HOH A O      1 ? 
HETATM 6395 H H1     . HOH D 4 .   ? 28.384  -11.499 -13.255 1    42.835 ? 1894 HOH A H1     1 ? 
HETATM 6396 H H2     . HOH D 4 .   ? 27.238  -10.451 -13.477 1    39.588 ? 1894 HOH A H2     1 ? 
HETATM 6397 O O      . HOH D 4 .   ? 27.18   -27.32  5.804   1    43.889 ? 1895 HOH A O      1 ? 
HETATM 6398 H H1     . HOH D 4 .   ? 26.965  -26.601 5.181   1    43.667 ? 1895 HOH A H1     1 ? 
HETATM 6399 H H2     . HOH D 4 .   ? 26.785  -27.084 6.657   1    44.284 ? 1895 HOH A H2     1 ? 
HETATM 6400 O O      . HOH D 4 .   ? 5.544   -35.843 28.856  1    30.376 ? 1896 HOH A O      1 ? 
HETATM 6401 H H1     . HOH D 4 .   ? 4.944   -35.745 28.091  1    32.124 ? 1896 HOH A H1     1 ? 
HETATM 6402 H H2     . HOH D 4 .   ? 5.503   -36.779 29.111  1    29.537 ? 1896 HOH A H2     1 ? 
HETATM 6403 O O      . HOH D 4 .   ? 0.903   -26.68  13.912  1    35.617 ? 1897 HOH A O      1 ? 
HETATM 6404 H H1     . HOH D 4 .   ? 1.39    -26.718 14.755  1    32.562 ? 1897 HOH A H1     1 ? 
HETATM 6405 H H2     . HOH D 4 .   ? 0.829   -25.736 13.684  1    34.397 ? 1897 HOH A H2     1 ? 
HETATM 6406 O O      . HOH D 4 .   ? 25.06   -29.882 1.125   1    53.965 ? 1898 HOH A O      1 ? 
HETATM 6407 H H1     . HOH D 4 .   ? 25.953  -29.762 1.496   1    53.748 ? 1898 HOH A H1     1 ? 
HETATM 6408 H H2     . HOH D 4 .   ? 25.065  -30.695 0.58    1    55.497 ? 1898 HOH A H2     1 ? 
HETATM 6409 O O      . HOH D 4 .   ? 1.084   -18.921 2.178   1    61.035 ? 1899 HOH A O      1 ? 
HETATM 6410 H H1     . HOH D 4 .   ? 0.84    -18.722 1.254   1    60.016 ? 1899 HOH A H1     1 ? 
HETATM 6411 H H2     . HOH D 4 .   ? 1.535   -19.791 2.194   1    57.765 ? 1899 HOH A H2     1 ? 
HETATM 6412 O O      . HOH D 4 .   ? 0.014   -19.445 5.853   1    44.945 ? 1900 HOH A O      1 ? 
HETATM 6413 H H1     . HOH D 4 .   ? 0.967   -19.662 5.79    1    40.589 ? 1900 HOH A H1     1 ? 
HETATM 6414 H H2     . HOH D 4 .   ? -0.171  -18.632 5.343   1    45.452 ? 1900 HOH A H2     1 ? 
HETATM 6415 O O      . HOH D 4 .   ? 10.69   -14.708 37.013  1    51.816 ? 1901 HOH A O      1 ? 
HETATM 6416 H H1     . HOH D 4 .   ? 10.728  -14.8   37.981  1    51.41  ? 1901 HOH A H1     1 ? 
HETATM 6417 H H2     . HOH D 4 .   ? 9.887   -14.201 36.813  1    52.191 ? 1901 HOH A H2     1 ? 
HETATM 6418 O O      . HOH D 4 .   ? 36.443  -33.651 22.808  1    44.918 ? 1902 HOH A O      1 ? 
HETATM 6419 H H1     . HOH D 4 .   ? 35.763  -33.888 23.462  1    50.566 ? 1902 HOH A H1     1 ? 
HETATM 6420 H H2     . HOH D 4 .   ? 36.736  -34.479 22.393  1    45.76  ? 1902 HOH A H2     1 ? 
HETATM 6421 O O      . HOH D 4 .   ? 30.467  -32.057 23.665  1    36.937 ? 1903 HOH A O      1 ? 
HETATM 6422 H H1     . HOH D 4 .   ? 31.24   -32.075 24.275  1    39.158 ? 1903 HOH A H1     1 ? 
HETATM 6423 H H2     . HOH D 4 .   ? 29.689  -31.731 24.167  1    34.98  ? 1903 HOH A H2     1 ? 
HETATM 6424 O O      . HOH D 4 .   ? 25.200  -0.878  6.323   1    25.311 ? 1904 HOH A O      1 ? 
HETATM 6425 H H1     . HOH D 4 .   ? 25.002  0.014   5.985   1    26.509 ? 1904 HOH A H1     1 ? 
HETATM 6426 H H2     . HOH D 4 .   ? 26.168  -1.023  6.160   1    24.227 ? 1904 HOH A H2     1 ? 
HETATM 6427 O O      . HOH D 4 .   ? 34.501  -2.557  -0.203  1    33.458 ? 1905 HOH A O      1 ? 
HETATM 6428 H H1     . HOH D 4 .   ? 35.357  -3.018  -0.099  1    31.514 ? 1905 HOH A H1     1 ? 
HETATM 6429 H H2     . HOH D 4 .   ? 33.807  -3.237  -0.291  1    33.416 ? 1905 HOH A H2     1 ? 
HETATM 6430 O O      . HOH D 4 .   ? 24.934  -12.932 -16.029 1    62.266 ? 1906 HOH A O      1 ? 
HETATM 6431 H H1     . HOH D 4 .   ? 24.832  -11.993 -16.293 1    59.689 ? 1906 HOH A H1     1 ? 
HETATM 6432 H H2     . HOH D 4 .   ? 25.758  -13.292 -16.412 1    55.46  ? 1906 HOH A H2     1 ? 
HETATM 6433 O O      . HOH D 4 .   ? 33.472  -34.338 20.872  1    38.754 ? 1907 HOH A O      1 ? 
HETATM 6434 H H1     . HOH D 4 .   ? 33.183  -35.048 20.27   1    39.198 ? 1907 HOH A H1     1 ? 
HETATM 6435 H H2     . HOH D 4 .   ? 33.382  -33.491 20.394  1    37.267 ? 1907 HOH A H2     1 ? 
HETATM 6436 O O      . HOH D 4 .   ? 25.903  -8.584  24.692  1    29.198 ? 1908 HOH A O      1 ? 
HETATM 6437 H H1     . HOH D 4 .   ? 26.253  -8.587  25.599  1    28.676 ? 1908 HOH A H1     1 ? 
HETATM 6438 H H2     . HOH D 4 .   ? 24.952  -8.817  24.746  1    28.107 ? 1908 HOH A H2     1 ? 
HETATM 6439 O O      . HOH D 4 .   ? 28.821  -8.158  -10.93  1    32.444 ? 1909 HOH A O      1 ? 
HETATM 6440 H H1     . HOH D 4 .   ? 29.523  -7.818  -10.348 1    30.916 ? 1909 HOH A H1     1 ? 
HETATM 6441 H H2     . HOH D 4 .   ? 28.419  -8.917  -10.477 1    31.719 ? 1909 HOH A H2     1 ? 
HETATM 6442 O O      . HOH D 4 .   ? 12.04   -16.861 39.581  1    43.725 ? 1910 HOH A O      1 ? 
HETATM 6443 H H1     . HOH D 4 .   ? 12.691  -16.121 39.625  1    40.863 ? 1910 HOH A H1     1 ? 
HETATM 6444 H H2     . HOH D 4 .   ? 11.253  -16.59  39.059  1    38.182 ? 1910 HOH A H2     1 ? 
HETATM 6445 O O      . HOH D 4 .   ? 3.714   -12.15  16.522  1    35.982 ? 1911 HOH A O      1 ? 
HETATM 6446 H H1     . HOH D 4 .   ? 4.318   -12.66  15.949  1    36.224 ? 1911 HOH A H1     1 ? 
HETATM 6447 H H2     . HOH D 4 .   ? 4.223   -11.421 16.92   1    32.835 ? 1911 HOH A H2     1 ? 
HETATM 6448 O O      . HOH D 4 .   ? 1.669   -16.891 8.392   1    31.433 ? 1912 HOH A O      1 ? 
HETATM 6449 H H1     . HOH D 4 .   ? 1.531   -15.996 8.033   1    30.795 ? 1912 HOH A H1     1 ? 
HETATM 6450 H H2     . HOH D 4 .   ? 1.17    -16.965 9.231   1    30.845 ? 1912 HOH A H2     1 ? 
HETATM 6451 O O      . HOH D 4 .   ? 21.495  -16.424 29.781  1    44.451 ? 1913 HOH A O      1 ? 
HETATM 6452 H H1     . HOH D 4 .   ? 21.834  -16.643 30.671  1    41.964 ? 1913 HOH A H1     1 ? 
HETATM 6453 H H2     . HOH D 4 .   ? 20.859  -15.681 29.846  1    42.317 ? 1913 HOH A H2     1 ? 
HETATM 6454 O O      . HOH D 4 .   ? 39.451  -5.344  4.406   1    27.37  ? 1914 HOH A O      1 ? 
HETATM 6455 H H1     . HOH D 4 .   ? 38.846  -4.814  4.950   1    26.771 ? 1914 HOH A H1     1 ? 
HETATM 6456 H H2     . HOH D 4 .   ? 40.363  -5.094  4.653   1    26.02  ? 1914 HOH A H2     1 ? 
HETATM 6457 O O      . HOH D 4 .   ? 30.664  -31.721 21.024  1    28.078 ? 1915 HOH A O      1 ? 
HETATM 6458 H H1     . HOH D 4 .   ? 30.61   -31.89  21.997  1    25.911 ? 1915 HOH A H1     1 ? 
HETATM 6459 H H2     . HOH D 4 .   ? 29.847  -32.055 20.58   1    27.01  ? 1915 HOH A H2     1 ? 
HETATM 6460 O O      . HOH D 4 .   ? -17.715 -23.038 18.824  1    35.612 ? 1916 HOH A O      1 ? 
HETATM 6461 H H1     . HOH D 4 .   ? -18.107 -22.678 19.637  0.56 35.14  ? 1916 HOH A H1     1 ? 
HETATM 6462 H H2     . HOH D 4 .   ? -17.803 -24.006 18.876  0.66 32.855 ? 1916 HOH A H2     1 ? 
HETATM 6463 O O      . HOH D 4 .   ? 13.991  -43.797 22.085  1    34.576 ? 1917 HOH A O      1 ? 
HETATM 6464 H H1     . HOH D 4 .   ? 14.241  -43.982 23.008  1    31.584 ? 1917 HOH A H1     1 ? 
HETATM 6465 H H2     . HOH D 4 .   ? 13.323  -44.451 21.795  1    32.378 ? 1917 HOH A H2     1 ? 
HETATM 6466 O O      . HOH D 4 .   ? 19.022  -35.127 9.189   1    33.836 ? 1918 HOH A O      1 ? 
HETATM 6467 H H1     . HOH D 4 .   ? 19.461  -35.122 10.057  1    33.109 ? 1918 HOH A H1     1 ? 
HETATM 6468 H H2     . HOH D 4 .   ? 18.638  -34.235 9.043   1    32.013 ? 1918 HOH A H2     1 ? 
HETATM 6469 O O      . HOH D 4 .   ? 26.278  -10.625 26.632  1    52.795 ? 1919 HOH A O      1 ? 
HETATM 6470 H H1     . HOH D 4 .   ? 26.059  -10.842 27.562  1    45.875 ? 1919 HOH A H1     1 ? 
HETATM 6471 H H2     . HOH D 4 .   ? 25.48   -10.746 26.079  1    50.94  ? 1919 HOH A H2     1 ? 
HETATM 6472 O O      . HOH D 4 .   ? 35.92   -18.661 29.486  1    28.33  ? 1920 HOH A O      1 ? 
HETATM 6473 H H1     . HOH D 4 .   ? 35.106  -18.238 29.163  1    27.428 ? 1920 HOH A H1     1 ? 
HETATM 6474 H H2     . HOH D 4 .   ? 35.759  -18.92  30.415  1    28.892 ? 1920 HOH A H2     1 ? 
HETATM 6475 O O      . HOH D 4 .   ? 27.192  -4.397  -6.498  1    39.886 ? 1921 HOH A O      1 ? 
HETATM 6476 H H1     . HOH D 4 .   ? 26.573  -3.963  -7.126  1    36.025 ? 1921 HOH A H1     1 ? 
HETATM 6477 H H2     . HOH D 4 .   ? 26.824  -5.260  -6.214  1    35.049 ? 1921 HOH A H2     1 ? 
HETATM 6478 O O      . HOH D 4 .   ? 24.875  -9.139  -15.477 1    32.801 ? 1922 HOH A O      1 ? 
HETATM 6479 H H1     . HOH D 4 .   ? 24.814  -8.287  -15.933 1    32.391 ? 1922 HOH A H1     1 ? 
HETATM 6480 H H2     . HOH D 4 .   ? 25.721  -9.130  -15.000 1    33.364 ? 1922 HOH A H2     1 ? 
HETATM 6481 O O      . HOH D 4 .   ? 29.351  -8.076  -5.756  1    38.789 ? 1923 HOH A O      1 ? 
HETATM 6482 H H1     . HOH D 4 .   ? 29.482  -8.824  -6.369  1    35.504 ? 1923 HOH A H1     1 ? 
HETATM 6483 H H2     . HOH D 4 .   ? 28.694  -7.471  -6.156  1    36.734 ? 1923 HOH A H2     1 ? 
HETATM 6484 O O      . HOH D 4 .   ? 8.376   -29.013 8.720   1    37.31  ? 1924 HOH A O      1 ? 
HETATM 6485 H H1     . HOH D 4 .   ? 7.906   -28.193 8.977   1    37.867 ? 1924 HOH A H1     1 ? 
HETATM 6486 H H2     . HOH D 4 .   ? 9.337   -28.826 8.653   1    37.916 ? 1924 HOH A H2     1 ? 
HETATM 6487 O O      . HOH D 4 .   ? 11.654  -34.647 16.742  1    34.252 ? 1925 HOH A O      1 ? 
HETATM 6488 H H1     . HOH D 4 .   ? 11.994  -34.259 15.914  1    34.07  ? 1925 HOH A H1     1 ? 
HETATM 6489 H H2     . HOH D 4 .   ? 11.795  -35.607 16.691  1    32.053 ? 1925 HOH A H2     1 ? 
HETATM 6490 O O      . HOH D 4 .   ? 2.515   2.116   23.086  1    52.581 ? 1926 HOH A O      1 ? 
HETATM 6491 H H1     . HOH D 4 .   ? 3.356   2.271   23.565  1    50.567 ? 1926 HOH A H1     1 ? 
HETATM 6492 H H2     . HOH D 4 .   ? 1.863   1.737   23.713  1    47.064 ? 1926 HOH A H2     1 ? 
HETATM 6493 O O      . HOH D 4 .   ? 24.504  -38.608 12.475  1    46.982 ? 1927 HOH A O      1 ? 
HETATM 6494 H H1     . HOH D 4 .   ? 24.11   -37.949 11.876  1    46.413 ? 1927 HOH A H1     1 ? 
HETATM 6495 H H2     . HOH D 4 .   ? 23.827  -38.853 13.132  1    45.984 ? 1927 HOH A H2     1 ? 
HETATM 6496 O O      . HOH D 4 .   ? 28      -10.204 24.168  1    37.023 ? 1928 HOH A O      1 ? 
HETATM 6497 H H1     . HOH D 4 .   ? 27.936  -9.261  24.403  1    37.392 ? 1928 HOH A H1     1 ? 
HETATM 6498 H H2     . HOH D 4 .   ? 27.32   -10.664 24.693  1    37.056 ? 1928 HOH A H2     1 ? 
HETATM 6499 O O      . HOH D 4 .   ? -4.175  -29.228 22.67   1    48.021 ? 1929 HOH A O      1 ? 
HETATM 6500 H H1     . HOH D 4 .   ? -3.789  -29.86  23.307  1    48.509 ? 1929 HOH A H1     1 ? 
HETATM 6501 H H2     . HOH D 4 .   ? -3.932  -29.53  21.779  1    45.019 ? 1929 HOH A H2     1 ? 
HETATM 6502 O O      . HOH D 4 .   ? 23.32   -32.117 -8.309  1    50.776 ? 1930 HOH A O      1 ? 
HETATM 6503 H H1     . HOH D 4 .   ? 23.928  -31.914 -9.044  1    51.106 ? 1930 HOH A H1     1 ? 
HETATM 6504 H H2     . HOH D 4 .   ? 22.539  -31.535 -8.399  1    47.372 ? 1930 HOH A H2     1 ? 
HETATM 6505 O O      . HOH D 4 .   ? 21.648  -38.847 10.210  1    50.663 ? 1931 HOH A O      1 ? 
HETATM 6506 H H1     . HOH D 4 .   ? 21.254  -39.631 9.785   1    51.439 ? 1931 HOH A H1     1 ? 
HETATM 6507 H H2     . HOH D 4 .   ? 22.580  -38.776 9.924   1    50.121 ? 1931 HOH A H2     1 ? 
HETATM 6508 O O      . HOH D 4 .   ? 13.986  -23.473 42.017  1    35.299 ? 1932 HOH A O      1 ? 
HETATM 6509 H H1     . HOH D 4 .   ? 14.31   -22.587 41.787  1    33.686 ? 1932 HOH A H1     1 ? 
HETATM 6510 H H2     . HOH D 4 .   ? 13.075  -23.555 41.679  1    32.43  ? 1932 HOH A H2     1 ? 
HETATM 6511 O O      . HOH D 4 .   ? 3.160   -29.500 8.144   1    47.291 ? 1933 HOH A O      1 ? 
HETATM 6512 H H1     . HOH D 4 .   ? 2.866   -29.620 7.220   1    43.394 ? 1933 HOH A H1     1 ? 
HETATM 6513 H H2     . HOH D 4 .   ? 3.842   -30.173 8.343   1    42.792 ? 1933 HOH A H2     1 ? 
HETATM 6514 O O      . HOH D 4 .   ? 29.169  -33.062 19.411  1    50.018 ? 1934 HOH A O      1 ? 
HETATM 6515 H H1     . HOH D 4 .   ? 28.755  -33.938 19.522  1    47.017 ? 1934 HOH A H1     1 ? 
HETATM 6516 H H2     . HOH D 4 .   ? 28.516  -32.472 18.982  1    49.33  ? 1934 HOH A H2     1 ? 
HETATM 6517 O O      . HOH D 4 .   ? 20.339  2.228   -1.419  1    46.286 ? 1935 HOH A O      1 ? 
HETATM 6518 H H1     . HOH D 4 .   ? 19.691  1.849   -0.798  1    41.583 ? 1935 HOH A H1     1 ? 
HETATM 6519 H H2     . HOH D 4 .   ? 20.195  3.196   -1.447  1    42.846 ? 1935 HOH A H2     1 ? 
HETATM 6520 O O      . HOH D 4 .   ? 3.262   -10.476 14.868  1    39.99  ? 1936 HOH A O      1 ? 
HETATM 6521 H H1     . HOH D 4 .   ? 3.908   -9.761  15.061  1    38.665 ? 1936 HOH A H1     1 ? 
HETATM 6522 H H2     . HOH D 4 .   ? 2.657   -10.172 14.157  1    41.525 ? 1936 HOH A H2     1 ? 
HETATM 6523 O O      . HOH D 4 .   ? 11.774  -31.619 39.375  1    20.804 ? 1937 HOH A O      1 ? 
HETATM 6524 H H1     . HOH D 4 .   ? 12.249  -32.169 40.031  1    19.872 ? 1937 HOH A H1     1 ? 
HETATM 6525 H H2     . HOH D 4 .   ? 11.844  -30.694 39.683  1    20.982 ? 1937 HOH A H2     1 ? 
HETATM 6526 O O      . HOH D 4 .   ? 23.732  -31.403 -1.419  1    64.258 ? 1938 HOH A O      1 ? 
HETATM 6527 H H1     . HOH D 4 .   ? 22.824  -31.05  -1.399  1    64.278 ? 1938 HOH A H1     1 ? 
HETATM 6528 H H2     . HOH D 4 .   ? 24.159  -31.074 -2.234  1    67.699 ? 1938 HOH A H2     1 ? 
HETATM 6529 O O      . HOH D 4 .   ? 7.139   -30.358 13.327  1    38.384 ? 1939 HOH A O      1 ? 
HETATM 6530 H H1     . HOH D 4 .   ? 7.216   -30.051 12.406  1    37.24  ? 1939 HOH A H1     1 ? 
HETATM 6531 H H2     . HOH D 4 .   ? 7.235   -29.577 13.902  1    36.483 ? 1939 HOH A H2     1 ? 
HETATM 6532 O O      . HOH D 4 .   ? 5.172   -28.682 11.667  1    37.683 ? 1940 HOH A O      1 ? 
HETATM 6533 H H1     . HOH D 4 .   ? 5.392   -27.768 11.387  1    36.673 ? 1940 HOH A H1     1 ? 
HETATM 6534 H H2     . HOH D 4 .   ? 4.199   -28.75  11.747  1    36.304 ? 1940 HOH A H2     1 ? 
HETATM 6535 O O      . HOH D 4 .   ? 20.269  -29.267 2.123   1    42.365 ? 1941 HOH A O      1 ? 
HETATM 6536 H H1     . HOH D 4 .   ? 20.518  -29.003 3.027   1    41.644 ? 1941 HOH A H1     1 ? 
HETATM 6537 H H2     . HOH D 4 .   ? 19.558  -28.669 1.827   1    41.804 ? 1941 HOH A H2     1 ? 
HETATM 6538 O O      . HOH D 4 .   ? 20.96   -31.585 -9.459  1    37.796 ? 1942 HOH A O      1 ? 
HETATM 6539 H H1     . HOH D 4 .   ? 20.151  -31.133 -9.143  1    36.807 ? 1942 HOH A H1     1 ? 
HETATM 6540 H H2     . HOH D 4 .   ? 20.899  -31.662 -10.429 1    37.234 ? 1942 HOH A H2     1 ? 
HETATM 6541 O O      . HOH D 4 .   ? 20.995  -6.941  25.435  1    49.304 ? 1943 HOH A O      1 ? 
HETATM 6542 H H1     . HOH D 4 .   ? 21.343  -7.834  25.608  1    47.093 ? 1943 HOH A H1     1 ? 
HETATM 6543 H H2     . HOH D 4 .   ? 20.034  -6.96   25.597  1    47.297 ? 1943 HOH A H2     1 ? 
HETATM 6544 O O      . HOH D 4 .   ? 15.193  -3.747  23.883  1    39.181 ? 1944 HOH A O      1 ? 
HETATM 6545 H H1     . HOH D 4 .   ? 16.128  -3.456  23.87   1    35.755 ? 1944 HOH A H1     1 ? 
HETATM 6546 H H2     . HOH D 4 .   ? 14.784  -3.42   24.708  1    38.058 ? 1944 HOH A H2     1 ? 
HETATM 6547 O O      . HOH D 4 .   ? 23.526  -9.56   28.539  1    40.118 ? 1945 HOH A O      1 ? 
HETATM 6548 H H1     . HOH D 4 .   ? 23.38   -10.087 29.348  1    39.451 ? 1945 HOH A H1     1 ? 
HETATM 6549 H H2     . HOH D 4 .   ? 22.651  -9.322  28.181  1    37.694 ? 1945 HOH A H2     1 ? 
HETATM 6550 O O      . HOH D 4 .   ? 28.853  -10.609 26.693  1    40.944 ? 1946 HOH A O      1 ? 
HETATM 6551 H H1     . HOH D 4 .   ? 29.356  -10.863 25.9    1    40.547 ? 1946 HOH A H1     1 ? 
HETATM 6552 H H2     . HOH D 4 .   ? 28.066  -10.115 26.392  1    39.306 ? 1946 HOH A H2     1 ? 
HETATM 6553 O O      . HOH D 4 .   ? 30.943  -10.774 28.446  1    59.756 ? 1947 HOH A O      1 ? 
HETATM 6554 H H1     . HOH D 4 .   ? 31.714  -10.254 28.136  1    55.991 ? 1947 HOH A H1     1 ? 
HETATM 6555 H H2     . HOH D 4 .   ? 30.13   -10.226 28.387  1    52.114 ? 1947 HOH A H2     1 ? 
# 
