data_9KHO
# 
_entry.id   9KHO 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9KHO         pdb_00009kho 10.2210/pdb9kho/pdb 
WWPDB D_1300053479 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-23 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9KHO 
_pdbx_database_status.recvd_initial_deposition_date   2024-11-11 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              2111623034@zjut.edu.cn 
_pdbx_contact_author.name_first         Xiaohe 
_pdbx_contact_author.name_last          Chu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-6398-5917 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Chen, Y.'  1 0009-0000-5499-837X 
'Chu, X.H.' 2 0000-0001-6398-5917 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Int.J.Biol.Macromol. 
_citation.journal_id_ASTM           IJBMDR 
_citation.journal_id_CSD            0708 
_citation.journal_id_ISSN           0141-8130 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            308 
_citation.language                  ? 
_citation.page_first                142543 
_citation.page_last                 142543 
_citation.title                     
;An AHL-lactonase mutant featuring a unique "tri-His" motif exhibits enhanced activity, stability and effectively controls plant soft rot.
;
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.ijbiomac.2025.142543 
_citation.pdbx_database_id_PubMed   40157672 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Chen, Y.' 1 ? 
primary 'Xie, X.'  2 ? 
primary 'Zhou, J.' 3 ? 
primary 'Dai, L.'  4 ? 
primary 'Chu, X.'  5 ? 
primary 'Liu, P.'  6 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'N-acylhomoserine lactonase' 29218.146 6    3.1.1.81 E77I/D157G/T243Y/H255L ? ? 
2 non-polymer syn 'NICKEL (II) ION'            58.693    12   ?        ?                      ? ? 
3 water       nat water                        18.015    1009 ?        ?                      ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MAAPRLYMFQTGTLKCRVCNIKMNAGLDDYEIPVPWYLITHPKGNVVIDGGCAVECASDPKGYWGDITSVYWPVMRIEEG
CVQALKAFGIEPADVRYVLHSHLHLDHTGATGRFPNAIHIVRRCEYEYAMAPDWFSAGGYIRADFDRPDVKWHLLEGHDD
GYDVFGDDTIRFIFTPGHAPGHSSFLLRLPETGPVLLAVDAAYTTDHWDEKALPGFLASTVDAVRSVRKLHALAEKTGAL
VVYGHDPEAWPTFRLAPEYYA
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MAAPRLYMFQTGTLKCRVCNIKMNAGLDDYEIPVPWYLITHPKGNVVIDGGCAVECASDPKGYWGDITSVYWPVMRIEEG
CVQALKAFGIEPADVRYVLHSHLHLDHTGATGRFPNAIHIVRRCEYEYAMAPDWFSAGGYIRADFDRPDVKWHLLEGHDD
GYDVFGDDTIRFIFTPGHAPGHSSFLLRLPETGPVLLAVDAAYTTDHWDEKALPGFLASTVDAVRSVRKLHALAEKTGAL
VVYGHDPEAWPTFRLAPEYYA
;
_entity_poly.pdbx_strand_id                 A,B,C,D,E,F 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'NICKEL (II) ION' NI  
3 water             HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   ALA n 
1 4   PRO n 
1 5   ARG n 
1 6   LEU n 
1 7   TYR n 
1 8   MET n 
1 9   PHE n 
1 10  GLN n 
1 11  THR n 
1 12  GLY n 
1 13  THR n 
1 14  LEU n 
1 15  LYS n 
1 16  CYS n 
1 17  ARG n 
1 18  VAL n 
1 19  CYS n 
1 20  ASN n 
1 21  ILE n 
1 22  LYS n 
1 23  MET n 
1 24  ASN n 
1 25  ALA n 
1 26  GLY n 
1 27  LEU n 
1 28  ASP n 
1 29  ASP n 
1 30  TYR n 
1 31  GLU n 
1 32  ILE n 
1 33  PRO n 
1 34  VAL n 
1 35  PRO n 
1 36  TRP n 
1 37  TYR n 
1 38  LEU n 
1 39  ILE n 
1 40  THR n 
1 41  HIS n 
1 42  PRO n 
1 43  LYS n 
1 44  GLY n 
1 45  ASN n 
1 46  VAL n 
1 47  VAL n 
1 48  ILE n 
1 49  ASP n 
1 50  GLY n 
1 51  GLY n 
1 52  CYS n 
1 53  ALA n 
1 54  VAL n 
1 55  GLU n 
1 56  CYS n 
1 57  ALA n 
1 58  SER n 
1 59  ASP n 
1 60  PRO n 
1 61  LYS n 
1 62  GLY n 
1 63  TYR n 
1 64  TRP n 
1 65  GLY n 
1 66  ASP n 
1 67  ILE n 
1 68  THR n 
1 69  SER n 
1 70  VAL n 
1 71  TYR n 
1 72  TRP n 
1 73  PRO n 
1 74  VAL n 
1 75  MET n 
1 76  ARG n 
1 77  ILE n 
1 78  GLU n 
1 79  GLU n 
1 80  GLY n 
1 81  CYS n 
1 82  VAL n 
1 83  GLN n 
1 84  ALA n 
1 85  LEU n 
1 86  LYS n 
1 87  ALA n 
1 88  PHE n 
1 89  GLY n 
1 90  ILE n 
1 91  GLU n 
1 92  PRO n 
1 93  ALA n 
1 94  ASP n 
1 95  VAL n 
1 96  ARG n 
1 97  TYR n 
1 98  VAL n 
1 99  LEU n 
1 100 HIS n 
1 101 SER n 
1 102 HIS n 
1 103 LEU n 
1 104 HIS n 
1 105 LEU n 
1 106 ASP n 
1 107 HIS n 
1 108 THR n 
1 109 GLY n 
1 110 ALA n 
1 111 THR n 
1 112 GLY n 
1 113 ARG n 
1 114 PHE n 
1 115 PRO n 
1 116 ASN n 
1 117 ALA n 
1 118 ILE n 
1 119 HIS n 
1 120 ILE n 
1 121 VAL n 
1 122 ARG n 
1 123 ARG n 
1 124 CYS n 
1 125 GLU n 
1 126 TYR n 
1 127 GLU n 
1 128 TYR n 
1 129 ALA n 
1 130 MET n 
1 131 ALA n 
1 132 PRO n 
1 133 ASP n 
1 134 TRP n 
1 135 PHE n 
1 136 SER n 
1 137 ALA n 
1 138 GLY n 
1 139 GLY n 
1 140 TYR n 
1 141 ILE n 
1 142 ARG n 
1 143 ALA n 
1 144 ASP n 
1 145 PHE n 
1 146 ASP n 
1 147 ARG n 
1 148 PRO n 
1 149 ASP n 
1 150 VAL n 
1 151 LYS n 
1 152 TRP n 
1 153 HIS n 
1 154 LEU n 
1 155 LEU n 
1 156 GLU n 
1 157 GLY n 
1 158 HIS n 
1 159 ASP n 
1 160 ASP n 
1 161 GLY n 
1 162 TYR n 
1 163 ASP n 
1 164 VAL n 
1 165 PHE n 
1 166 GLY n 
1 167 ASP n 
1 168 ASP n 
1 169 THR n 
1 170 ILE n 
1 171 ARG n 
1 172 PHE n 
1 173 ILE n 
1 174 PHE n 
1 175 THR n 
1 176 PRO n 
1 177 GLY n 
1 178 HIS n 
1 179 ALA n 
1 180 PRO n 
1 181 GLY n 
1 182 HIS n 
1 183 SER n 
1 184 SER n 
1 185 PHE n 
1 186 LEU n 
1 187 LEU n 
1 188 ARG n 
1 189 LEU n 
1 190 PRO n 
1 191 GLU n 
1 192 THR n 
1 193 GLY n 
1 194 PRO n 
1 195 VAL n 
1 196 LEU n 
1 197 LEU n 
1 198 ALA n 
1 199 VAL n 
1 200 ASP n 
1 201 ALA n 
1 202 ALA n 
1 203 TYR n 
1 204 THR n 
1 205 THR n 
1 206 ASP n 
1 207 HIS n 
1 208 TRP n 
1 209 ASP n 
1 210 GLU n 
1 211 LYS n 
1 212 ALA n 
1 213 LEU n 
1 214 PRO n 
1 215 GLY n 
1 216 PHE n 
1 217 LEU n 
1 218 ALA n 
1 219 SER n 
1 220 THR n 
1 221 VAL n 
1 222 ASP n 
1 223 ALA n 
1 224 VAL n 
1 225 ARG n 
1 226 SER n 
1 227 VAL n 
1 228 ARG n 
1 229 LYS n 
1 230 LEU n 
1 231 HIS n 
1 232 ALA n 
1 233 LEU n 
1 234 ALA n 
1 235 GLU n 
1 236 LYS n 
1 237 THR n 
1 238 GLY n 
1 239 ALA n 
1 240 LEU n 
1 241 VAL n 
1 242 VAL n 
1 243 TYR n 
1 244 GLY n 
1 245 HIS n 
1 246 ASP n 
1 247 PRO n 
1 248 GLU n 
1 249 ALA n 
1 250 TRP n 
1 251 PRO n 
1 252 THR n 
1 253 PHE n 
1 254 ARG n 
1 255 LEU n 
1 256 ALA n 
1 257 PRO n 
1 258 GLU n 
1 259 TYR n 
1 260 TYR n 
1 261 ALA n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   261 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ahlX 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Salinicola salarius' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     430457 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE           ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE          ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE        ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'   ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE          ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE         ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'   ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE           ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE         ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER             ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE        ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE           ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE            ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE        ? 'C5 H11 N O2 S'  149.211 
NI  non-polymer         . 'NICKEL (II) ION' ? 'Ni 2'           58.693  
PHE 'L-peptide linking' y PHENYLALANINE     ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE           ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE            ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE         ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN        ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE          ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE            ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   ?   ?   ?   A . n 
A 1 3   ALA 3   3   3   ALA ALA A . n 
A 1 4   PRO 4   4   4   PRO PRO A . n 
A 1 5   ARG 5   5   5   ARG ARG A . n 
A 1 6   LEU 6   6   6   LEU LEU A . n 
A 1 7   TYR 7   7   7   TYR TYR A . n 
A 1 8   MET 8   8   8   MET MET A . n 
A 1 9   PHE 9   9   9   PHE PHE A . n 
A 1 10  GLN 10  10  10  GLN GLN A . n 
A 1 11  THR 11  11  11  THR THR A . n 
A 1 12  GLY 12  12  12  GLY GLY A . n 
A 1 13  THR 13  13  13  THR THR A . n 
A 1 14  LEU 14  14  14  LEU LEU A . n 
A 1 15  LYS 15  15  15  LYS LYS A . n 
A 1 16  CYS 16  16  16  CYS CYS A . n 
A 1 17  ARG 17  17  17  ARG ARG A . n 
A 1 18  VAL 18  18  18  VAL VAL A . n 
A 1 19  CYS 19  19  19  CYS CYS A . n 
A 1 20  ASN 20  20  20  ASN ASN A . n 
A 1 21  ILE 21  21  21  ILE ILE A . n 
A 1 22  LYS 22  22  22  LYS LYS A . n 
A 1 23  MET 23  23  23  MET MET A . n 
A 1 24  ASN 24  24  24  ASN ASN A . n 
A 1 25  ALA 25  25  25  ALA ALA A . n 
A 1 26  GLY 26  26  26  GLY GLY A . n 
A 1 27  LEU 27  27  27  LEU LEU A . n 
A 1 28  ASP 28  28  28  ASP ASP A . n 
A 1 29  ASP 29  29  29  ASP ASP A . n 
A 1 30  TYR 30  30  30  TYR TYR A . n 
A 1 31  GLU 31  31  31  GLU GLU A . n 
A 1 32  ILE 32  32  32  ILE ILE A . n 
A 1 33  PRO 33  33  33  PRO PRO A . n 
A 1 34  VAL 34  34  34  VAL VAL A . n 
A 1 35  PRO 35  35  35  PRO PRO A . n 
A 1 36  TRP 36  36  36  TRP TRP A . n 
A 1 37  TYR 37  37  37  TYR TYR A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  ILE 39  39  39  ILE ILE A . n 
A 1 40  THR 40  40  40  THR THR A . n 
A 1 41  HIS 41  41  41  HIS HIS A . n 
A 1 42  PRO 42  42  42  PRO PRO A . n 
A 1 43  LYS 43  43  43  LYS LYS A . n 
A 1 44  GLY 44  44  44  GLY GLY A . n 
A 1 45  ASN 45  45  45  ASN ASN A . n 
A 1 46  VAL 46  46  46  VAL VAL A . n 
A 1 47  VAL 47  47  47  VAL VAL A . n 
A 1 48  ILE 48  48  48  ILE ILE A . n 
A 1 49  ASP 49  49  49  ASP ASP A . n 
A 1 50  GLY 50  50  50  GLY GLY A . n 
A 1 51  GLY 51  51  51  GLY GLY A . n 
A 1 52  CYS 52  52  52  CYS CYS A . n 
A 1 53  ALA 53  53  53  ALA ALA A . n 
A 1 54  VAL 54  54  54  VAL VAL A . n 
A 1 55  GLU 55  55  55  GLU GLU A . n 
A 1 56  CYS 56  56  56  CYS CYS A . n 
A 1 57  ALA 57  57  57  ALA ALA A . n 
A 1 58  SER 58  58  58  SER SER A . n 
A 1 59  ASP 59  59  59  ASP ASP A . n 
A 1 60  PRO 60  60  60  PRO PRO A . n 
A 1 61  LYS 61  61  61  LYS LYS A . n 
A 1 62  GLY 62  62  62  GLY GLY A . n 
A 1 63  TYR 63  63  63  TYR TYR A . n 
A 1 64  TRP 64  64  64  TRP TRP A . n 
A 1 65  GLY 65  65  65  GLY GLY A . n 
A 1 66  ASP 66  66  66  ASP ASP A . n 
A 1 67  ILE 67  67  67  ILE ILE A . n 
A 1 68  THR 68  68  68  THR THR A . n 
A 1 69  SER 69  69  69  SER SER A . n 
A 1 70  VAL 70  70  70  VAL VAL A . n 
A 1 71  TYR 71  71  71  TYR TYR A . n 
A 1 72  TRP 72  72  72  TRP TRP A . n 
A 1 73  PRO 73  73  73  PRO PRO A . n 
A 1 74  VAL 74  74  74  VAL VAL A . n 
A 1 75  MET 75  75  75  MET MET A . n 
A 1 76  ARG 76  76  76  ARG ARG A . n 
A 1 77  ILE 77  77  77  ILE ILE A . n 
A 1 78  GLU 78  78  78  GLU GLU A . n 
A 1 79  GLU 79  79  79  GLU GLU A . n 
A 1 80  GLY 80  80  80  GLY GLY A . n 
A 1 81  CYS 81  81  81  CYS CYS A . n 
A 1 82  VAL 82  82  82  VAL VAL A . n 
A 1 83  GLN 83  83  83  GLN GLN A . n 
A 1 84  ALA 84  84  84  ALA ALA A . n 
A 1 85  LEU 85  85  85  LEU LEU A . n 
A 1 86  LYS 86  86  86  LYS LYS A . n 
A 1 87  ALA 87  87  87  ALA ALA A . n 
A 1 88  PHE 88  88  88  PHE PHE A . n 
A 1 89  GLY 89  89  89  GLY GLY A . n 
A 1 90  ILE 90  90  90  ILE ILE A . n 
A 1 91  GLU 91  91  91  GLU GLU A . n 
A 1 92  PRO 92  92  92  PRO PRO A . n 
A 1 93  ALA 93  93  93  ALA ALA A . n 
A 1 94  ASP 94  94  94  ASP ASP A . n 
A 1 95  VAL 95  95  95  VAL VAL A . n 
A 1 96  ARG 96  96  96  ARG ARG A . n 
A 1 97  TYR 97  97  97  TYR TYR A . n 
A 1 98  VAL 98  98  98  VAL VAL A . n 
A 1 99  LEU 99  99  99  LEU LEU A . n 
A 1 100 HIS 100 100 100 HIS HIS A . n 
A 1 101 SER 101 101 101 SER SER A . n 
A 1 102 HIS 102 102 102 HIS HIS A . n 
A 1 103 LEU 103 103 103 LEU LEU A . n 
A 1 104 HIS 104 104 104 HIS HIS A . n 
A 1 105 LEU 105 105 105 LEU LEU A . n 
A 1 106 ASP 106 106 106 ASP ASP A . n 
A 1 107 HIS 107 107 107 HIS HIS A . n 
A 1 108 THR 108 108 108 THR THR A . n 
A 1 109 GLY 109 109 109 GLY GLY A . n 
A 1 110 ALA 110 110 110 ALA ALA A . n 
A 1 111 THR 111 111 111 THR THR A . n 
A 1 112 GLY 112 112 112 GLY GLY A . n 
A 1 113 ARG 113 113 113 ARG ARG A . n 
A 1 114 PHE 114 114 114 PHE PHE A . n 
A 1 115 PRO 115 115 115 PRO PRO A . n 
A 1 116 ASN 116 116 116 ASN ASN A . n 
A 1 117 ALA 117 117 117 ALA ALA A . n 
A 1 118 ILE 118 118 118 ILE ILE A . n 
A 1 119 HIS 119 119 119 HIS HIS A . n 
A 1 120 ILE 120 120 120 ILE ILE A . n 
A 1 121 VAL 121 121 121 VAL VAL A . n 
A 1 122 ARG 122 122 122 ARG ARG A . n 
A 1 123 ARG 123 123 123 ARG ARG A . n 
A 1 124 CYS 124 124 124 CYS CYS A . n 
A 1 125 GLU 125 125 125 GLU GLU A . n 
A 1 126 TYR 126 126 126 TYR TYR A . n 
A 1 127 GLU 127 127 127 GLU GLU A . n 
A 1 128 TYR 128 128 128 TYR TYR A . n 
A 1 129 ALA 129 129 129 ALA ALA A . n 
A 1 130 MET 130 130 130 MET MET A . n 
A 1 131 ALA 131 131 131 ALA ALA A . n 
A 1 132 PRO 132 132 132 PRO PRO A . n 
A 1 133 ASP 133 133 133 ASP ASP A . n 
A 1 134 TRP 134 134 134 TRP TRP A . n 
A 1 135 PHE 135 135 135 PHE PHE A . n 
A 1 136 SER 136 136 136 SER SER A . n 
A 1 137 ALA 137 137 137 ALA ALA A . n 
A 1 138 GLY 138 138 138 GLY GLY A . n 
A 1 139 GLY 139 139 139 GLY GLY A . n 
A 1 140 TYR 140 140 140 TYR TYR A . n 
A 1 141 ILE 141 141 141 ILE ILE A . n 
A 1 142 ARG 142 142 142 ARG ARG A . n 
A 1 143 ALA 143 143 143 ALA ALA A . n 
A 1 144 ASP 144 144 144 ASP ASP A . n 
A 1 145 PHE 145 145 145 PHE PHE A . n 
A 1 146 ASP 146 146 146 ASP ASP A . n 
A 1 147 ARG 147 147 147 ARG ARG A . n 
A 1 148 PRO 148 148 148 PRO PRO A . n 
A 1 149 ASP 149 149 149 ASP ASP A . n 
A 1 150 VAL 150 150 150 VAL VAL A . n 
A 1 151 LYS 151 151 151 LYS LYS A . n 
A 1 152 TRP 152 152 152 TRP TRP A . n 
A 1 153 HIS 153 153 153 HIS HIS A . n 
A 1 154 LEU 154 154 154 LEU LEU A . n 
A 1 155 LEU 155 155 155 LEU LEU A . n 
A 1 156 GLU 156 156 156 GLU GLU A . n 
A 1 157 GLY 157 157 157 GLY GLY A . n 
A 1 158 HIS 158 158 158 HIS HIS A . n 
A 1 159 ASP 159 159 159 ASP ASP A . n 
A 1 160 ASP 160 160 160 ASP ASP A . n 
A 1 161 GLY 161 161 161 GLY GLY A . n 
A 1 162 TYR 162 162 162 TYR TYR A . n 
A 1 163 ASP 163 163 163 ASP ASP A . n 
A 1 164 VAL 164 164 164 VAL VAL A . n 
A 1 165 PHE 165 165 165 PHE PHE A . n 
A 1 166 GLY 166 166 166 GLY GLY A . n 
A 1 167 ASP 167 167 167 ASP ASP A . n 
A 1 168 ASP 168 168 168 ASP ASP A . n 
A 1 169 THR 169 169 169 THR THR A . n 
A 1 170 ILE 170 170 170 ILE ILE A . n 
A 1 171 ARG 171 171 171 ARG ARG A . n 
A 1 172 PHE 172 172 172 PHE PHE A . n 
A 1 173 ILE 173 173 173 ILE ILE A . n 
A 1 174 PHE 174 174 174 PHE PHE A . n 
A 1 175 THR 175 175 175 THR THR A . n 
A 1 176 PRO 176 176 176 PRO PRO A . n 
A 1 177 GLY 177 177 177 GLY GLY A . n 
A 1 178 HIS 178 178 178 HIS HIS A . n 
A 1 179 ALA 179 179 179 ALA ALA A . n 
A 1 180 PRO 180 180 180 PRO PRO A . n 
A 1 181 GLY 181 181 181 GLY GLY A . n 
A 1 182 HIS 182 182 182 HIS HIS A . n 
A 1 183 SER 183 183 183 SER SER A . n 
A 1 184 SER 184 184 184 SER SER A . n 
A 1 185 PHE 185 185 185 PHE PHE A . n 
A 1 186 LEU 186 186 186 LEU LEU A . n 
A 1 187 LEU 187 187 187 LEU LEU A . n 
A 1 188 ARG 188 188 188 ARG ARG A . n 
A 1 189 LEU 189 189 189 LEU LEU A . n 
A 1 190 PRO 190 190 190 PRO PRO A . n 
A 1 191 GLU 191 191 191 GLU GLU A . n 
A 1 192 THR 192 192 192 THR THR A . n 
A 1 193 GLY 193 193 193 GLY GLY A . n 
A 1 194 PRO 194 194 194 PRO PRO A . n 
A 1 195 VAL 195 195 195 VAL VAL A . n 
A 1 196 LEU 196 196 196 LEU LEU A . n 
A 1 197 LEU 197 197 197 LEU LEU A . n 
A 1 198 ALA 198 198 198 ALA ALA A . n 
A 1 199 VAL 199 199 199 VAL VAL A . n 
A 1 200 ASP 200 200 200 ASP ASP A . n 
A 1 201 ALA 201 201 201 ALA ALA A . n 
A 1 202 ALA 202 202 202 ALA ALA A . n 
A 1 203 TYR 203 203 203 TYR TYR A . n 
A 1 204 THR 204 204 204 THR THR A . n 
A 1 205 THR 205 205 205 THR THR A . n 
A 1 206 ASP 206 206 206 ASP ASP A . n 
A 1 207 HIS 207 207 207 HIS HIS A . n 
A 1 208 TRP 208 208 208 TRP TRP A . n 
A 1 209 ASP 209 209 209 ASP ASP A . n 
A 1 210 GLU 210 210 210 GLU GLU A . n 
A 1 211 LYS 211 211 211 LYS LYS A . n 
A 1 212 ALA 212 212 212 ALA ALA A . n 
A 1 213 LEU 213 213 213 LEU LEU A . n 
A 1 214 PRO 214 214 214 PRO PRO A . n 
A 1 215 GLY 215 215 215 GLY GLY A . n 
A 1 216 PHE 216 216 216 PHE PHE A . n 
A 1 217 LEU 217 217 217 LEU LEU A . n 
A 1 218 ALA 218 218 218 ALA ALA A . n 
A 1 219 SER 219 219 219 SER SER A . n 
A 1 220 THR 220 220 220 THR THR A . n 
A 1 221 VAL 221 221 221 VAL VAL A . n 
A 1 222 ASP 222 222 222 ASP ASP A . n 
A 1 223 ALA 223 223 223 ALA ALA A . n 
A 1 224 VAL 224 224 224 VAL VAL A . n 
A 1 225 ARG 225 225 225 ARG ARG A . n 
A 1 226 SER 226 226 226 SER SER A . n 
A 1 227 VAL 227 227 227 VAL VAL A . n 
A 1 228 ARG 228 228 228 ARG ARG A . n 
A 1 229 LYS 229 229 229 LYS LYS A . n 
A 1 230 LEU 230 230 230 LEU LEU A . n 
A 1 231 HIS 231 231 231 HIS HIS A . n 
A 1 232 ALA 232 232 232 ALA ALA A . n 
A 1 233 LEU 233 233 233 LEU LEU A . n 
A 1 234 ALA 234 234 234 ALA ALA A . n 
A 1 235 GLU 235 235 235 GLU GLU A . n 
A 1 236 LYS 236 236 236 LYS LYS A . n 
A 1 237 THR 237 237 237 THR THR A . n 
A 1 238 GLY 238 238 238 GLY GLY A . n 
A 1 239 ALA 239 239 239 ALA ALA A . n 
A 1 240 LEU 240 240 240 LEU LEU A . n 
A 1 241 VAL 241 241 241 VAL VAL A . n 
A 1 242 VAL 242 242 242 VAL VAL A . n 
A 1 243 TYR 243 243 243 TYR TYR A . n 
A 1 244 GLY 244 244 244 GLY GLY A . n 
A 1 245 HIS 245 245 245 HIS HIS A . n 
A 1 246 ASP 246 246 246 ASP ASP A . n 
A 1 247 PRO 247 247 247 PRO PRO A . n 
A 1 248 GLU 248 248 248 GLU GLU A . n 
A 1 249 ALA 249 249 249 ALA ALA A . n 
A 1 250 TRP 250 250 250 TRP TRP A . n 
A 1 251 PRO 251 251 251 PRO PRO A . n 
A 1 252 THR 252 252 252 THR THR A . n 
A 1 253 PHE 253 253 253 PHE PHE A . n 
A 1 254 ARG 254 254 254 ARG ARG A . n 
A 1 255 LEU 255 255 255 LEU LEU A . n 
A 1 256 ALA 256 256 ?   ?   ?   A . n 
A 1 257 PRO 257 257 ?   ?   ?   A . n 
A 1 258 GLU 258 258 ?   ?   ?   A . n 
A 1 259 TYR 259 259 ?   ?   ?   A . n 
A 1 260 TYR 260 260 ?   ?   ?   A . n 
A 1 261 ALA 261 261 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   ALA 2   2   ?   ?   ?   B . n 
B 1 3   ALA 3   3   ?   ?   ?   B . n 
B 1 4   PRO 4   4   4   PRO PRO B . n 
B 1 5   ARG 5   5   5   ARG ARG B . n 
B 1 6   LEU 6   6   6   LEU LEU B . n 
B 1 7   TYR 7   7   7   TYR TYR B . n 
B 1 8   MET 8   8   8   MET MET B . n 
B 1 9   PHE 9   9   9   PHE PHE B . n 
B 1 10  GLN 10  10  10  GLN GLN B . n 
B 1 11  THR 11  11  11  THR THR B . n 
B 1 12  GLY 12  12  12  GLY GLY B . n 
B 1 13  THR 13  13  13  THR THR B . n 
B 1 14  LEU 14  14  14  LEU LEU B . n 
B 1 15  LYS 15  15  15  LYS LYS B . n 
B 1 16  CYS 16  16  16  CYS CYS B . n 
B 1 17  ARG 17  17  17  ARG ARG B . n 
B 1 18  VAL 18  18  18  VAL VAL B . n 
B 1 19  CYS 19  19  19  CYS CYS B . n 
B 1 20  ASN 20  20  20  ASN ASN B . n 
B 1 21  ILE 21  21  21  ILE ILE B . n 
B 1 22  LYS 22  22  22  LYS LYS B . n 
B 1 23  MET 23  23  23  MET MET B . n 
B 1 24  ASN 24  24  24  ASN ASN B . n 
B 1 25  ALA 25  25  25  ALA ALA B . n 
B 1 26  GLY 26  26  26  GLY GLY B . n 
B 1 27  LEU 27  27  27  LEU LEU B . n 
B 1 28  ASP 28  28  28  ASP ASP B . n 
B 1 29  ASP 29  29  29  ASP ASP B . n 
B 1 30  TYR 30  30  30  TYR TYR B . n 
B 1 31  GLU 31  31  31  GLU GLU B . n 
B 1 32  ILE 32  32  32  ILE ILE B . n 
B 1 33  PRO 33  33  33  PRO PRO B . n 
B 1 34  VAL 34  34  34  VAL VAL B . n 
B 1 35  PRO 35  35  35  PRO PRO B . n 
B 1 36  TRP 36  36  36  TRP TRP B . n 
B 1 37  TYR 37  37  37  TYR TYR B . n 
B 1 38  LEU 38  38  38  LEU LEU B . n 
B 1 39  ILE 39  39  39  ILE ILE B . n 
B 1 40  THR 40  40  40  THR THR B . n 
B 1 41  HIS 41  41  41  HIS HIS B . n 
B 1 42  PRO 42  42  42  PRO PRO B . n 
B 1 43  LYS 43  43  43  LYS LYS B . n 
B 1 44  GLY 44  44  44  GLY GLY B . n 
B 1 45  ASN 45  45  45  ASN ASN B . n 
B 1 46  VAL 46  46  46  VAL VAL B . n 
B 1 47  VAL 47  47  47  VAL VAL B . n 
B 1 48  ILE 48  48  48  ILE ILE B . n 
B 1 49  ASP 49  49  49  ASP ASP B . n 
B 1 50  GLY 50  50  50  GLY GLY B . n 
B 1 51  GLY 51  51  51  GLY GLY B . n 
B 1 52  CYS 52  52  52  CYS CYS B . n 
B 1 53  ALA 53  53  53  ALA ALA B . n 
B 1 54  VAL 54  54  54  VAL VAL B . n 
B 1 55  GLU 55  55  55  GLU GLU B . n 
B 1 56  CYS 56  56  56  CYS CYS B . n 
B 1 57  ALA 57  57  57  ALA ALA B . n 
B 1 58  SER 58  58  58  SER SER B . n 
B 1 59  ASP 59  59  59  ASP ASP B . n 
B 1 60  PRO 60  60  60  PRO PRO B . n 
B 1 61  LYS 61  61  61  LYS LYS B . n 
B 1 62  GLY 62  62  62  GLY GLY B . n 
B 1 63  TYR 63  63  63  TYR TYR B . n 
B 1 64  TRP 64  64  64  TRP TRP B . n 
B 1 65  GLY 65  65  65  GLY GLY B . n 
B 1 66  ASP 66  66  66  ASP ASP B . n 
B 1 67  ILE 67  67  67  ILE ILE B . n 
B 1 68  THR 68  68  68  THR THR B . n 
B 1 69  SER 69  69  69  SER SER B . n 
B 1 70  VAL 70  70  70  VAL VAL B . n 
B 1 71  TYR 71  71  71  TYR TYR B . n 
B 1 72  TRP 72  72  72  TRP TRP B . n 
B 1 73  PRO 73  73  73  PRO PRO B . n 
B 1 74  VAL 74  74  74  VAL VAL B . n 
B 1 75  MET 75  75  75  MET MET B . n 
B 1 76  ARG 76  76  76  ARG ARG B . n 
B 1 77  ILE 77  77  77  ILE ILE B . n 
B 1 78  GLU 78  78  78  GLU GLU B . n 
B 1 79  GLU 79  79  79  GLU GLU B . n 
B 1 80  GLY 80  80  80  GLY GLY B . n 
B 1 81  CYS 81  81  81  CYS CYS B . n 
B 1 82  VAL 82  82  82  VAL VAL B . n 
B 1 83  GLN 83  83  83  GLN GLN B . n 
B 1 84  ALA 84  84  84  ALA ALA B . n 
B 1 85  LEU 85  85  85  LEU LEU B . n 
B 1 86  LYS 86  86  86  LYS LYS B . n 
B 1 87  ALA 87  87  87  ALA ALA B . n 
B 1 88  PHE 88  88  88  PHE PHE B . n 
B 1 89  GLY 89  89  89  GLY GLY B . n 
B 1 90  ILE 90  90  90  ILE ILE B . n 
B 1 91  GLU 91  91  91  GLU GLU B . n 
B 1 92  PRO 92  92  92  PRO PRO B . n 
B 1 93  ALA 93  93  93  ALA ALA B . n 
B 1 94  ASP 94  94  94  ASP ASP B . n 
B 1 95  VAL 95  95  95  VAL VAL B . n 
B 1 96  ARG 96  96  96  ARG ARG B . n 
B 1 97  TYR 97  97  97  TYR TYR B . n 
B 1 98  VAL 98  98  98  VAL VAL B . n 
B 1 99  LEU 99  99  99  LEU LEU B . n 
B 1 100 HIS 100 100 100 HIS HIS B . n 
B 1 101 SER 101 101 101 SER SER B . n 
B 1 102 HIS 102 102 102 HIS HIS B . n 
B 1 103 LEU 103 103 103 LEU LEU B . n 
B 1 104 HIS 104 104 104 HIS HIS B . n 
B 1 105 LEU 105 105 105 LEU LEU B . n 
B 1 106 ASP 106 106 106 ASP ASP B . n 
B 1 107 HIS 107 107 107 HIS HIS B . n 
B 1 108 THR 108 108 108 THR THR B . n 
B 1 109 GLY 109 109 109 GLY GLY B . n 
B 1 110 ALA 110 110 110 ALA ALA B . n 
B 1 111 THR 111 111 111 THR THR B . n 
B 1 112 GLY 112 112 112 GLY GLY B . n 
B 1 113 ARG 113 113 113 ARG ARG B . n 
B 1 114 PHE 114 114 114 PHE PHE B . n 
B 1 115 PRO 115 115 115 PRO PRO B . n 
B 1 116 ASN 116 116 116 ASN ASN B . n 
B 1 117 ALA 117 117 117 ALA ALA B . n 
B 1 118 ILE 118 118 118 ILE ILE B . n 
B 1 119 HIS 119 119 119 HIS HIS B . n 
B 1 120 ILE 120 120 120 ILE ILE B . n 
B 1 121 VAL 121 121 121 VAL VAL B . n 
B 1 122 ARG 122 122 122 ARG ARG B . n 
B 1 123 ARG 123 123 123 ARG ARG B . n 
B 1 124 CYS 124 124 124 CYS CYS B . n 
B 1 125 GLU 125 125 125 GLU GLU B . n 
B 1 126 TYR 126 126 126 TYR TYR B . n 
B 1 127 GLU 127 127 127 GLU GLU B . n 
B 1 128 TYR 128 128 128 TYR TYR B . n 
B 1 129 ALA 129 129 129 ALA ALA B . n 
B 1 130 MET 130 130 130 MET MET B . n 
B 1 131 ALA 131 131 131 ALA ALA B . n 
B 1 132 PRO 132 132 132 PRO PRO B . n 
B 1 133 ASP 133 133 133 ASP ASP B . n 
B 1 134 TRP 134 134 134 TRP TRP B . n 
B 1 135 PHE 135 135 135 PHE PHE B . n 
B 1 136 SER 136 136 136 SER SER B . n 
B 1 137 ALA 137 137 137 ALA ALA B . n 
B 1 138 GLY 138 138 138 GLY GLY B . n 
B 1 139 GLY 139 139 139 GLY GLY B . n 
B 1 140 TYR 140 140 140 TYR TYR B . n 
B 1 141 ILE 141 141 141 ILE ILE B . n 
B 1 142 ARG 142 142 142 ARG ARG B . n 
B 1 143 ALA 143 143 143 ALA ALA B . n 
B 1 144 ASP 144 144 144 ASP ASP B . n 
B 1 145 PHE 145 145 145 PHE PHE B . n 
B 1 146 ASP 146 146 146 ASP ASP B . n 
B 1 147 ARG 147 147 147 ARG ARG B . n 
B 1 148 PRO 148 148 148 PRO PRO B . n 
B 1 149 ASP 149 149 149 ASP ASP B . n 
B 1 150 VAL 150 150 150 VAL VAL B . n 
B 1 151 LYS 151 151 151 LYS LYS B . n 
B 1 152 TRP 152 152 152 TRP TRP B . n 
B 1 153 HIS 153 153 153 HIS HIS B . n 
B 1 154 LEU 154 154 154 LEU LEU B . n 
B 1 155 LEU 155 155 155 LEU LEU B . n 
B 1 156 GLU 156 156 156 GLU GLU B . n 
B 1 157 GLY 157 157 157 GLY GLY B . n 
B 1 158 HIS 158 158 158 HIS HIS B . n 
B 1 159 ASP 159 159 159 ASP ASP B . n 
B 1 160 ASP 160 160 160 ASP ASP B . n 
B 1 161 GLY 161 161 161 GLY GLY B . n 
B 1 162 TYR 162 162 162 TYR TYR B . n 
B 1 163 ASP 163 163 163 ASP ASP B . n 
B 1 164 VAL 164 164 164 VAL VAL B . n 
B 1 165 PHE 165 165 165 PHE PHE B . n 
B 1 166 GLY 166 166 166 GLY GLY B . n 
B 1 167 ASP 167 167 167 ASP ASP B . n 
B 1 168 ASP 168 168 168 ASP ASP B . n 
B 1 169 THR 169 169 169 THR THR B . n 
B 1 170 ILE 170 170 170 ILE ILE B . n 
B 1 171 ARG 171 171 171 ARG ARG B . n 
B 1 172 PHE 172 172 172 PHE PHE B . n 
B 1 173 ILE 173 173 173 ILE ILE B . n 
B 1 174 PHE 174 174 174 PHE PHE B . n 
B 1 175 THR 175 175 175 THR THR B . n 
B 1 176 PRO 176 176 176 PRO PRO B . n 
B 1 177 GLY 177 177 177 GLY GLY B . n 
B 1 178 HIS 178 178 178 HIS HIS B . n 
B 1 179 ALA 179 179 179 ALA ALA B . n 
B 1 180 PRO 180 180 180 PRO PRO B . n 
B 1 181 GLY 181 181 181 GLY GLY B . n 
B 1 182 HIS 182 182 182 HIS HIS B . n 
B 1 183 SER 183 183 183 SER SER B . n 
B 1 184 SER 184 184 184 SER SER B . n 
B 1 185 PHE 185 185 185 PHE PHE B . n 
B 1 186 LEU 186 186 186 LEU LEU B . n 
B 1 187 LEU 187 187 187 LEU LEU B . n 
B 1 188 ARG 188 188 188 ARG ARG B . n 
B 1 189 LEU 189 189 189 LEU LEU B . n 
B 1 190 PRO 190 190 190 PRO PRO B . n 
B 1 191 GLU 191 191 191 GLU GLU B . n 
B 1 192 THR 192 192 192 THR THR B . n 
B 1 193 GLY 193 193 193 GLY GLY B . n 
B 1 194 PRO 194 194 194 PRO PRO B . n 
B 1 195 VAL 195 195 195 VAL VAL B . n 
B 1 196 LEU 196 196 196 LEU LEU B . n 
B 1 197 LEU 197 197 197 LEU LEU B . n 
B 1 198 ALA 198 198 198 ALA ALA B . n 
B 1 199 VAL 199 199 199 VAL VAL B . n 
B 1 200 ASP 200 200 200 ASP ASP B . n 
B 1 201 ALA 201 201 201 ALA ALA B . n 
B 1 202 ALA 202 202 202 ALA ALA B . n 
B 1 203 TYR 203 203 203 TYR TYR B . n 
B 1 204 THR 204 204 204 THR THR B . n 
B 1 205 THR 205 205 205 THR THR B . n 
B 1 206 ASP 206 206 206 ASP ASP B . n 
B 1 207 HIS 207 207 207 HIS HIS B . n 
B 1 208 TRP 208 208 208 TRP TRP B . n 
B 1 209 ASP 209 209 209 ASP ASP B . n 
B 1 210 GLU 210 210 210 GLU GLU B . n 
B 1 211 LYS 211 211 211 LYS LYS B . n 
B 1 212 ALA 212 212 212 ALA ALA B . n 
B 1 213 LEU 213 213 213 LEU LEU B . n 
B 1 214 PRO 214 214 214 PRO PRO B . n 
B 1 215 GLY 215 215 215 GLY GLY B . n 
B 1 216 PHE 216 216 216 PHE PHE B . n 
B 1 217 LEU 217 217 217 LEU LEU B . n 
B 1 218 ALA 218 218 218 ALA ALA B . n 
B 1 219 SER 219 219 219 SER SER B . n 
B 1 220 THR 220 220 220 THR THR B . n 
B 1 221 VAL 221 221 221 VAL VAL B . n 
B 1 222 ASP 222 222 222 ASP ASP B . n 
B 1 223 ALA 223 223 223 ALA ALA B . n 
B 1 224 VAL 224 224 224 VAL VAL B . n 
B 1 225 ARG 225 225 225 ARG ARG B . n 
B 1 226 SER 226 226 226 SER SER B . n 
B 1 227 VAL 227 227 227 VAL VAL B . n 
B 1 228 ARG 228 228 228 ARG ARG B . n 
B 1 229 LYS 229 229 229 LYS LYS B . n 
B 1 230 LEU 230 230 230 LEU LEU B . n 
B 1 231 HIS 231 231 231 HIS HIS B . n 
B 1 232 ALA 232 232 232 ALA ALA B . n 
B 1 233 LEU 233 233 233 LEU LEU B . n 
B 1 234 ALA 234 234 234 ALA ALA B . n 
B 1 235 GLU 235 235 235 GLU GLU B . n 
B 1 236 LYS 236 236 236 LYS LYS B . n 
B 1 237 THR 237 237 237 THR THR B . n 
B 1 238 GLY 238 238 238 GLY GLY B . n 
B 1 239 ALA 239 239 239 ALA ALA B . n 
B 1 240 LEU 240 240 240 LEU LEU B . n 
B 1 241 VAL 241 241 241 VAL VAL B . n 
B 1 242 VAL 242 242 242 VAL VAL B . n 
B 1 243 TYR 243 243 243 TYR TYR B . n 
B 1 244 GLY 244 244 244 GLY GLY B . n 
B 1 245 HIS 245 245 245 HIS HIS B . n 
B 1 246 ASP 246 246 246 ASP ASP B . n 
B 1 247 PRO 247 247 247 PRO PRO B . n 
B 1 248 GLU 248 248 248 GLU GLU B . n 
B 1 249 ALA 249 249 249 ALA ALA B . n 
B 1 250 TRP 250 250 250 TRP TRP B . n 
B 1 251 PRO 251 251 251 PRO PRO B . n 
B 1 252 THR 252 252 252 THR THR B . n 
B 1 253 PHE 253 253 253 PHE PHE B . n 
B 1 254 ARG 254 254 254 ARG ARG B . n 
B 1 255 LEU 255 255 255 LEU LEU B . n 
B 1 256 ALA 256 256 ?   ?   ?   B . n 
B 1 257 PRO 257 257 ?   ?   ?   B . n 
B 1 258 GLU 258 258 ?   ?   ?   B . n 
B 1 259 TYR 259 259 ?   ?   ?   B . n 
B 1 260 TYR 260 260 ?   ?   ?   B . n 
B 1 261 ALA 261 261 ?   ?   ?   B . n 
C 1 1   MET 1   1   ?   ?   ?   C . n 
C 1 2   ALA 2   2   ?   ?   ?   C . n 
C 1 3   ALA 3   3   ?   ?   ?   C . n 
C 1 4   PRO 4   4   ?   ?   ?   C . n 
C 1 5   ARG 5   5   5   ARG ARG C . n 
C 1 6   LEU 6   6   6   LEU LEU C . n 
C 1 7   TYR 7   7   7   TYR TYR C . n 
C 1 8   MET 8   8   8   MET MET C . n 
C 1 9   PHE 9   9   9   PHE PHE C . n 
C 1 10  GLN 10  10  10  GLN GLN C . n 
C 1 11  THR 11  11  11  THR THR C . n 
C 1 12  GLY 12  12  12  GLY GLY C . n 
C 1 13  THR 13  13  13  THR THR C . n 
C 1 14  LEU 14  14  14  LEU LEU C . n 
C 1 15  LYS 15  15  15  LYS LYS C . n 
C 1 16  CYS 16  16  16  CYS CYS C . n 
C 1 17  ARG 17  17  17  ARG ARG C . n 
C 1 18  VAL 18  18  18  VAL VAL C . n 
C 1 19  CYS 19  19  19  CYS CYS C . n 
C 1 20  ASN 20  20  20  ASN ASN C . n 
C 1 21  ILE 21  21  21  ILE ILE C . n 
C 1 22  LYS 22  22  22  LYS LYS C . n 
C 1 23  MET 23  23  23  MET MET C . n 
C 1 24  ASN 24  24  24  ASN ASN C . n 
C 1 25  ALA 25  25  25  ALA ALA C . n 
C 1 26  GLY 26  26  26  GLY GLY C . n 
C 1 27  LEU 27  27  27  LEU LEU C . n 
C 1 28  ASP 28  28  28  ASP ASP C . n 
C 1 29  ASP 29  29  29  ASP ASP C . n 
C 1 30  TYR 30  30  30  TYR TYR C . n 
C 1 31  GLU 31  31  31  GLU GLU C . n 
C 1 32  ILE 32  32  32  ILE ILE C . n 
C 1 33  PRO 33  33  33  PRO PRO C . n 
C 1 34  VAL 34  34  34  VAL VAL C . n 
C 1 35  PRO 35  35  35  PRO PRO C . n 
C 1 36  TRP 36  36  36  TRP TRP C . n 
C 1 37  TYR 37  37  37  TYR TYR C . n 
C 1 38  LEU 38  38  38  LEU LEU C . n 
C 1 39  ILE 39  39  39  ILE ILE C . n 
C 1 40  THR 40  40  40  THR THR C . n 
C 1 41  HIS 41  41  41  HIS HIS C . n 
C 1 42  PRO 42  42  42  PRO PRO C . n 
C 1 43  LYS 43  43  43  LYS LYS C . n 
C 1 44  GLY 44  44  44  GLY GLY C . n 
C 1 45  ASN 45  45  45  ASN ASN C . n 
C 1 46  VAL 46  46  46  VAL VAL C . n 
C 1 47  VAL 47  47  47  VAL VAL C . n 
C 1 48  ILE 48  48  48  ILE ILE C . n 
C 1 49  ASP 49  49  49  ASP ASP C . n 
C 1 50  GLY 50  50  50  GLY GLY C . n 
C 1 51  GLY 51  51  51  GLY GLY C . n 
C 1 52  CYS 52  52  52  CYS CYS C . n 
C 1 53  ALA 53  53  53  ALA ALA C . n 
C 1 54  VAL 54  54  54  VAL VAL C . n 
C 1 55  GLU 55  55  55  GLU GLU C . n 
C 1 56  CYS 56  56  56  CYS CYS C . n 
C 1 57  ALA 57  57  57  ALA ALA C . n 
C 1 58  SER 58  58  58  SER SER C . n 
C 1 59  ASP 59  59  59  ASP ASP C . n 
C 1 60  PRO 60  60  60  PRO PRO C . n 
C 1 61  LYS 61  61  61  LYS LYS C . n 
C 1 62  GLY 62  62  62  GLY GLY C . n 
C 1 63  TYR 63  63  63  TYR TYR C . n 
C 1 64  TRP 64  64  64  TRP TRP C . n 
C 1 65  GLY 65  65  65  GLY GLY C . n 
C 1 66  ASP 66  66  66  ASP ASP C . n 
C 1 67  ILE 67  67  67  ILE ILE C . n 
C 1 68  THR 68  68  68  THR THR C . n 
C 1 69  SER 69  69  69  SER SER C . n 
C 1 70  VAL 70  70  70  VAL VAL C . n 
C 1 71  TYR 71  71  71  TYR TYR C . n 
C 1 72  TRP 72  72  72  TRP TRP C . n 
C 1 73  PRO 73  73  73  PRO PRO C . n 
C 1 74  VAL 74  74  74  VAL VAL C . n 
C 1 75  MET 75  75  75  MET MET C . n 
C 1 76  ARG 76  76  76  ARG ARG C . n 
C 1 77  ILE 77  77  77  ILE ILE C . n 
C 1 78  GLU 78  78  78  GLU GLU C . n 
C 1 79  GLU 79  79  79  GLU GLU C . n 
C 1 80  GLY 80  80  80  GLY GLY C . n 
C 1 81  CYS 81  81  81  CYS CYS C . n 
C 1 82  VAL 82  82  82  VAL VAL C . n 
C 1 83  GLN 83  83  83  GLN GLN C . n 
C 1 84  ALA 84  84  84  ALA ALA C . n 
C 1 85  LEU 85  85  85  LEU LEU C . n 
C 1 86  LYS 86  86  86  LYS LYS C . n 
C 1 87  ALA 87  87  87  ALA ALA C . n 
C 1 88  PHE 88  88  88  PHE PHE C . n 
C 1 89  GLY 89  89  89  GLY GLY C . n 
C 1 90  ILE 90  90  90  ILE ILE C . n 
C 1 91  GLU 91  91  91  GLU GLU C . n 
C 1 92  PRO 92  92  92  PRO PRO C . n 
C 1 93  ALA 93  93  93  ALA ALA C . n 
C 1 94  ASP 94  94  94  ASP ASP C . n 
C 1 95  VAL 95  95  95  VAL VAL C . n 
C 1 96  ARG 96  96  96  ARG ARG C . n 
C 1 97  TYR 97  97  97  TYR TYR C . n 
C 1 98  VAL 98  98  98  VAL VAL C . n 
C 1 99  LEU 99  99  99  LEU LEU C . n 
C 1 100 HIS 100 100 100 HIS HIS C . n 
C 1 101 SER 101 101 101 SER SER C . n 
C 1 102 HIS 102 102 102 HIS HIS C . n 
C 1 103 LEU 103 103 103 LEU LEU C . n 
C 1 104 HIS 104 104 104 HIS HIS C . n 
C 1 105 LEU 105 105 105 LEU LEU C . n 
C 1 106 ASP 106 106 106 ASP ASP C . n 
C 1 107 HIS 107 107 107 HIS HIS C . n 
C 1 108 THR 108 108 108 THR THR C . n 
C 1 109 GLY 109 109 109 GLY GLY C . n 
C 1 110 ALA 110 110 110 ALA ALA C . n 
C 1 111 THR 111 111 111 THR THR C . n 
C 1 112 GLY 112 112 112 GLY GLY C . n 
C 1 113 ARG 113 113 113 ARG ARG C . n 
C 1 114 PHE 114 114 114 PHE PHE C . n 
C 1 115 PRO 115 115 115 PRO PRO C . n 
C 1 116 ASN 116 116 116 ASN ASN C . n 
C 1 117 ALA 117 117 117 ALA ALA C . n 
C 1 118 ILE 118 118 118 ILE ILE C . n 
C 1 119 HIS 119 119 119 HIS HIS C . n 
C 1 120 ILE 120 120 120 ILE ILE C . n 
C 1 121 VAL 121 121 121 VAL VAL C . n 
C 1 122 ARG 122 122 122 ARG ARG C . n 
C 1 123 ARG 123 123 123 ARG ARG C . n 
C 1 124 CYS 124 124 124 CYS CYS C . n 
C 1 125 GLU 125 125 125 GLU GLU C . n 
C 1 126 TYR 126 126 126 TYR TYR C . n 
C 1 127 GLU 127 127 127 GLU GLU C . n 
C 1 128 TYR 128 128 128 TYR TYR C . n 
C 1 129 ALA 129 129 129 ALA ALA C . n 
C 1 130 MET 130 130 130 MET MET C . n 
C 1 131 ALA 131 131 131 ALA ALA C . n 
C 1 132 PRO 132 132 132 PRO PRO C . n 
C 1 133 ASP 133 133 133 ASP ASP C . n 
C 1 134 TRP 134 134 134 TRP TRP C . n 
C 1 135 PHE 135 135 135 PHE PHE C . n 
C 1 136 SER 136 136 136 SER SER C . n 
C 1 137 ALA 137 137 137 ALA ALA C . n 
C 1 138 GLY 138 138 138 GLY GLY C . n 
C 1 139 GLY 139 139 139 GLY GLY C . n 
C 1 140 TYR 140 140 140 TYR TYR C . n 
C 1 141 ILE 141 141 141 ILE ILE C . n 
C 1 142 ARG 142 142 142 ARG ARG C . n 
C 1 143 ALA 143 143 143 ALA ALA C . n 
C 1 144 ASP 144 144 144 ASP ASP C . n 
C 1 145 PHE 145 145 145 PHE PHE C . n 
C 1 146 ASP 146 146 146 ASP ASP C . n 
C 1 147 ARG 147 147 147 ARG ARG C . n 
C 1 148 PRO 148 148 148 PRO PRO C . n 
C 1 149 ASP 149 149 149 ASP ASP C . n 
C 1 150 VAL 150 150 150 VAL VAL C . n 
C 1 151 LYS 151 151 151 LYS LYS C . n 
C 1 152 TRP 152 152 152 TRP TRP C . n 
C 1 153 HIS 153 153 153 HIS HIS C . n 
C 1 154 LEU 154 154 154 LEU LEU C . n 
C 1 155 LEU 155 155 155 LEU LEU C . n 
C 1 156 GLU 156 156 156 GLU GLU C . n 
C 1 157 GLY 157 157 157 GLY GLY C . n 
C 1 158 HIS 158 158 158 HIS HIS C . n 
C 1 159 ASP 159 159 159 ASP ASP C . n 
C 1 160 ASP 160 160 160 ASP ASP C . n 
C 1 161 GLY 161 161 161 GLY GLY C . n 
C 1 162 TYR 162 162 162 TYR TYR C . n 
C 1 163 ASP 163 163 163 ASP ASP C . n 
C 1 164 VAL 164 164 164 VAL VAL C . n 
C 1 165 PHE 165 165 165 PHE PHE C . n 
C 1 166 GLY 166 166 166 GLY GLY C . n 
C 1 167 ASP 167 167 167 ASP ASP C . n 
C 1 168 ASP 168 168 168 ASP ASP C . n 
C 1 169 THR 169 169 169 THR THR C . n 
C 1 170 ILE 170 170 170 ILE ILE C . n 
C 1 171 ARG 171 171 171 ARG ARG C . n 
C 1 172 PHE 172 172 172 PHE PHE C . n 
C 1 173 ILE 173 173 173 ILE ILE C . n 
C 1 174 PHE 174 174 174 PHE PHE C . n 
C 1 175 THR 175 175 175 THR THR C . n 
C 1 176 PRO 176 176 176 PRO PRO C . n 
C 1 177 GLY 177 177 177 GLY GLY C . n 
C 1 178 HIS 178 178 178 HIS HIS C . n 
C 1 179 ALA 179 179 179 ALA ALA C . n 
C 1 180 PRO 180 180 180 PRO PRO C . n 
C 1 181 GLY 181 181 181 GLY GLY C . n 
C 1 182 HIS 182 182 182 HIS HIS C . n 
C 1 183 SER 183 183 183 SER SER C . n 
C 1 184 SER 184 184 184 SER SER C . n 
C 1 185 PHE 185 185 185 PHE PHE C . n 
C 1 186 LEU 186 186 186 LEU LEU C . n 
C 1 187 LEU 187 187 187 LEU LEU C . n 
C 1 188 ARG 188 188 188 ARG ARG C . n 
C 1 189 LEU 189 189 189 LEU LEU C . n 
C 1 190 PRO 190 190 190 PRO PRO C . n 
C 1 191 GLU 191 191 191 GLU GLU C . n 
C 1 192 THR 192 192 192 THR THR C . n 
C 1 193 GLY 193 193 193 GLY GLY C . n 
C 1 194 PRO 194 194 194 PRO PRO C . n 
C 1 195 VAL 195 195 195 VAL VAL C . n 
C 1 196 LEU 196 196 196 LEU LEU C . n 
C 1 197 LEU 197 197 197 LEU LEU C . n 
C 1 198 ALA 198 198 198 ALA ALA C . n 
C 1 199 VAL 199 199 199 VAL VAL C . n 
C 1 200 ASP 200 200 200 ASP ASP C . n 
C 1 201 ALA 201 201 201 ALA ALA C . n 
C 1 202 ALA 202 202 202 ALA ALA C . n 
C 1 203 TYR 203 203 203 TYR TYR C . n 
C 1 204 THR 204 204 204 THR THR C . n 
C 1 205 THR 205 205 205 THR THR C . n 
C 1 206 ASP 206 206 206 ASP ASP C . n 
C 1 207 HIS 207 207 207 HIS HIS C . n 
C 1 208 TRP 208 208 208 TRP TRP C . n 
C 1 209 ASP 209 209 209 ASP ASP C . n 
C 1 210 GLU 210 210 210 GLU GLU C . n 
C 1 211 LYS 211 211 211 LYS LYS C . n 
C 1 212 ALA 212 212 212 ALA ALA C . n 
C 1 213 LEU 213 213 213 LEU LEU C . n 
C 1 214 PRO 214 214 214 PRO PRO C . n 
C 1 215 GLY 215 215 215 GLY GLY C . n 
C 1 216 PHE 216 216 216 PHE PHE C . n 
C 1 217 LEU 217 217 217 LEU LEU C . n 
C 1 218 ALA 218 218 218 ALA ALA C . n 
C 1 219 SER 219 219 219 SER SER C . n 
C 1 220 THR 220 220 220 THR THR C . n 
C 1 221 VAL 221 221 221 VAL VAL C . n 
C 1 222 ASP 222 222 222 ASP ASP C . n 
C 1 223 ALA 223 223 223 ALA ALA C . n 
C 1 224 VAL 224 224 224 VAL VAL C . n 
C 1 225 ARG 225 225 225 ARG ARG C . n 
C 1 226 SER 226 226 226 SER SER C . n 
C 1 227 VAL 227 227 227 VAL VAL C . n 
C 1 228 ARG 228 228 228 ARG ARG C . n 
C 1 229 LYS 229 229 229 LYS LYS C . n 
C 1 230 LEU 230 230 230 LEU LEU C . n 
C 1 231 HIS 231 231 231 HIS HIS C . n 
C 1 232 ALA 232 232 232 ALA ALA C . n 
C 1 233 LEU 233 233 233 LEU LEU C . n 
C 1 234 ALA 234 234 234 ALA ALA C . n 
C 1 235 GLU 235 235 235 GLU GLU C . n 
C 1 236 LYS 236 236 236 LYS LYS C . n 
C 1 237 THR 237 237 237 THR THR C . n 
C 1 238 GLY 238 238 238 GLY GLY C . n 
C 1 239 ALA 239 239 239 ALA ALA C . n 
C 1 240 LEU 240 240 240 LEU LEU C . n 
C 1 241 VAL 241 241 241 VAL VAL C . n 
C 1 242 VAL 242 242 242 VAL VAL C . n 
C 1 243 TYR 243 243 243 TYR TYR C . n 
C 1 244 GLY 244 244 244 GLY GLY C . n 
C 1 245 HIS 245 245 245 HIS HIS C . n 
C 1 246 ASP 246 246 246 ASP ASP C . n 
C 1 247 PRO 247 247 247 PRO PRO C . n 
C 1 248 GLU 248 248 248 GLU GLU C . n 
C 1 249 ALA 249 249 249 ALA ALA C . n 
C 1 250 TRP 250 250 250 TRP TRP C . n 
C 1 251 PRO 251 251 251 PRO PRO C . n 
C 1 252 THR 252 252 252 THR THR C . n 
C 1 253 PHE 253 253 253 PHE PHE C . n 
C 1 254 ARG 254 254 254 ARG ARG C . n 
C 1 255 LEU 255 255 255 LEU LEU C . n 
C 1 256 ALA 256 256 256 ALA ALA C . n 
C 1 257 PRO 257 257 ?   ?   ?   C . n 
C 1 258 GLU 258 258 ?   ?   ?   C . n 
C 1 259 TYR 259 259 ?   ?   ?   C . n 
C 1 260 TYR 260 260 ?   ?   ?   C . n 
C 1 261 ALA 261 261 ?   ?   ?   C . n 
D 1 1   MET 1   1   ?   ?   ?   D . n 
D 1 2   ALA 2   2   ?   ?   ?   D . n 
D 1 3   ALA 3   3   3   ALA ALA D . n 
D 1 4   PRO 4   4   4   PRO PRO D . n 
D 1 5   ARG 5   5   5   ARG ARG D . n 
D 1 6   LEU 6   6   6   LEU LEU D . n 
D 1 7   TYR 7   7   7   TYR TYR D . n 
D 1 8   MET 8   8   8   MET MET D . n 
D 1 9   PHE 9   9   9   PHE PHE D . n 
D 1 10  GLN 10  10  10  GLN GLN D . n 
D 1 11  THR 11  11  11  THR THR D . n 
D 1 12  GLY 12  12  12  GLY GLY D . n 
D 1 13  THR 13  13  13  THR THR D . n 
D 1 14  LEU 14  14  14  LEU LEU D . n 
D 1 15  LYS 15  15  15  LYS LYS D . n 
D 1 16  CYS 16  16  16  CYS CYS D . n 
D 1 17  ARG 17  17  17  ARG ARG D . n 
D 1 18  VAL 18  18  18  VAL VAL D . n 
D 1 19  CYS 19  19  19  CYS CYS D . n 
D 1 20  ASN 20  20  20  ASN ASN D . n 
D 1 21  ILE 21  21  21  ILE ILE D . n 
D 1 22  LYS 22  22  22  LYS LYS D . n 
D 1 23  MET 23  23  23  MET MET D . n 
D 1 24  ASN 24  24  24  ASN ASN D . n 
D 1 25  ALA 25  25  25  ALA ALA D . n 
D 1 26  GLY 26  26  26  GLY GLY D . n 
D 1 27  LEU 27  27  27  LEU LEU D . n 
D 1 28  ASP 28  28  28  ASP ASP D . n 
D 1 29  ASP 29  29  29  ASP ASP D . n 
D 1 30  TYR 30  30  30  TYR TYR D . n 
D 1 31  GLU 31  31  31  GLU GLU D . n 
D 1 32  ILE 32  32  32  ILE ILE D . n 
D 1 33  PRO 33  33  33  PRO PRO D . n 
D 1 34  VAL 34  34  34  VAL VAL D . n 
D 1 35  PRO 35  35  35  PRO PRO D . n 
D 1 36  TRP 36  36  36  TRP TRP D . n 
D 1 37  TYR 37  37  37  TYR TYR D . n 
D 1 38  LEU 38  38  38  LEU LEU D . n 
D 1 39  ILE 39  39  39  ILE ILE D . n 
D 1 40  THR 40  40  40  THR THR D . n 
D 1 41  HIS 41  41  41  HIS HIS D . n 
D 1 42  PRO 42  42  42  PRO PRO D . n 
D 1 43  LYS 43  43  43  LYS LYS D . n 
D 1 44  GLY 44  44  44  GLY GLY D . n 
D 1 45  ASN 45  45  45  ASN ASN D . n 
D 1 46  VAL 46  46  46  VAL VAL D . n 
D 1 47  VAL 47  47  47  VAL VAL D . n 
D 1 48  ILE 48  48  48  ILE ILE D . n 
D 1 49  ASP 49  49  49  ASP ASP D . n 
D 1 50  GLY 50  50  50  GLY GLY D . n 
D 1 51  GLY 51  51  51  GLY GLY D . n 
D 1 52  CYS 52  52  52  CYS CYS D . n 
D 1 53  ALA 53  53  53  ALA ALA D . n 
D 1 54  VAL 54  54  54  VAL VAL D . n 
D 1 55  GLU 55  55  55  GLU GLU D . n 
D 1 56  CYS 56  56  56  CYS CYS D . n 
D 1 57  ALA 57  57  57  ALA ALA D . n 
D 1 58  SER 58  58  58  SER SER D . n 
D 1 59  ASP 59  59  59  ASP ASP D . n 
D 1 60  PRO 60  60  60  PRO PRO D . n 
D 1 61  LYS 61  61  61  LYS LYS D . n 
D 1 62  GLY 62  62  62  GLY GLY D . n 
D 1 63  TYR 63  63  63  TYR TYR D . n 
D 1 64  TRP 64  64  64  TRP TRP D . n 
D 1 65  GLY 65  65  65  GLY GLY D . n 
D 1 66  ASP 66  66  66  ASP ASP D . n 
D 1 67  ILE 67  67  67  ILE ILE D . n 
D 1 68  THR 68  68  68  THR THR D . n 
D 1 69  SER 69  69  69  SER SER D . n 
D 1 70  VAL 70  70  70  VAL VAL D . n 
D 1 71  TYR 71  71  71  TYR TYR D . n 
D 1 72  TRP 72  72  72  TRP TRP D . n 
D 1 73  PRO 73  73  73  PRO PRO D . n 
D 1 74  VAL 74  74  74  VAL VAL D . n 
D 1 75  MET 75  75  75  MET MET D . n 
D 1 76  ARG 76  76  76  ARG ARG D . n 
D 1 77  ILE 77  77  77  ILE ILE D . n 
D 1 78  GLU 78  78  78  GLU GLU D . n 
D 1 79  GLU 79  79  79  GLU GLU D . n 
D 1 80  GLY 80  80  80  GLY GLY D . n 
D 1 81  CYS 81  81  81  CYS CYS D . n 
D 1 82  VAL 82  82  82  VAL VAL D . n 
D 1 83  GLN 83  83  83  GLN GLN D . n 
D 1 84  ALA 84  84  84  ALA ALA D . n 
D 1 85  LEU 85  85  85  LEU LEU D . n 
D 1 86  LYS 86  86  86  LYS LYS D . n 
D 1 87  ALA 87  87  87  ALA ALA D . n 
D 1 88  PHE 88  88  88  PHE PHE D . n 
D 1 89  GLY 89  89  89  GLY GLY D . n 
D 1 90  ILE 90  90  90  ILE ILE D . n 
D 1 91  GLU 91  91  91  GLU GLU D . n 
D 1 92  PRO 92  92  92  PRO PRO D . n 
D 1 93  ALA 93  93  93  ALA ALA D . n 
D 1 94  ASP 94  94  94  ASP ASP D . n 
D 1 95  VAL 95  95  95  VAL VAL D . n 
D 1 96  ARG 96  96  96  ARG ARG D . n 
D 1 97  TYR 97  97  97  TYR TYR D . n 
D 1 98  VAL 98  98  98  VAL VAL D . n 
D 1 99  LEU 99  99  99  LEU LEU D . n 
D 1 100 HIS 100 100 100 HIS HIS D . n 
D 1 101 SER 101 101 101 SER SER D . n 
D 1 102 HIS 102 102 102 HIS HIS D . n 
D 1 103 LEU 103 103 103 LEU LEU D . n 
D 1 104 HIS 104 104 104 HIS HIS D . n 
D 1 105 LEU 105 105 105 LEU LEU D . n 
D 1 106 ASP 106 106 106 ASP ASP D . n 
D 1 107 HIS 107 107 107 HIS HIS D . n 
D 1 108 THR 108 108 108 THR THR D . n 
D 1 109 GLY 109 109 109 GLY GLY D . n 
D 1 110 ALA 110 110 110 ALA ALA D . n 
D 1 111 THR 111 111 111 THR THR D . n 
D 1 112 GLY 112 112 112 GLY GLY D . n 
D 1 113 ARG 113 113 113 ARG ARG D . n 
D 1 114 PHE 114 114 114 PHE PHE D . n 
D 1 115 PRO 115 115 115 PRO PRO D . n 
D 1 116 ASN 116 116 116 ASN ASN D . n 
D 1 117 ALA 117 117 117 ALA ALA D . n 
D 1 118 ILE 118 118 118 ILE ILE D . n 
D 1 119 HIS 119 119 119 HIS HIS D . n 
D 1 120 ILE 120 120 120 ILE ILE D . n 
D 1 121 VAL 121 121 121 VAL VAL D . n 
D 1 122 ARG 122 122 122 ARG ARG D . n 
D 1 123 ARG 123 123 123 ARG ARG D . n 
D 1 124 CYS 124 124 124 CYS CYS D . n 
D 1 125 GLU 125 125 125 GLU GLU D . n 
D 1 126 TYR 126 126 126 TYR TYR D . n 
D 1 127 GLU 127 127 127 GLU GLU D . n 
D 1 128 TYR 128 128 128 TYR TYR D . n 
D 1 129 ALA 129 129 129 ALA ALA D . n 
D 1 130 MET 130 130 130 MET MET D . n 
D 1 131 ALA 131 131 131 ALA ALA D . n 
D 1 132 PRO 132 132 132 PRO PRO D . n 
D 1 133 ASP 133 133 133 ASP ASP D . n 
D 1 134 TRP 134 134 134 TRP TRP D . n 
D 1 135 PHE 135 135 135 PHE PHE D . n 
D 1 136 SER 136 136 136 SER SER D . n 
D 1 137 ALA 137 137 137 ALA ALA D . n 
D 1 138 GLY 138 138 138 GLY GLY D . n 
D 1 139 GLY 139 139 139 GLY GLY D . n 
D 1 140 TYR 140 140 140 TYR TYR D . n 
D 1 141 ILE 141 141 141 ILE ILE D . n 
D 1 142 ARG 142 142 142 ARG ARG D . n 
D 1 143 ALA 143 143 143 ALA ALA D . n 
D 1 144 ASP 144 144 144 ASP ASP D . n 
D 1 145 PHE 145 145 145 PHE PHE D . n 
D 1 146 ASP 146 146 146 ASP ASP D . n 
D 1 147 ARG 147 147 147 ARG ARG D . n 
D 1 148 PRO 148 148 148 PRO PRO D . n 
D 1 149 ASP 149 149 149 ASP ASP D . n 
D 1 150 VAL 150 150 150 VAL VAL D . n 
D 1 151 LYS 151 151 151 LYS LYS D . n 
D 1 152 TRP 152 152 152 TRP TRP D . n 
D 1 153 HIS 153 153 153 HIS HIS D . n 
D 1 154 LEU 154 154 154 LEU LEU D . n 
D 1 155 LEU 155 155 155 LEU LEU D . n 
D 1 156 GLU 156 156 156 GLU GLU D . n 
D 1 157 GLY 157 157 157 GLY GLY D . n 
D 1 158 HIS 158 158 158 HIS HIS D . n 
D 1 159 ASP 159 159 159 ASP ASP D . n 
D 1 160 ASP 160 160 160 ASP ASP D . n 
D 1 161 GLY 161 161 161 GLY GLY D . n 
D 1 162 TYR 162 162 162 TYR TYR D . n 
D 1 163 ASP 163 163 163 ASP ASP D . n 
D 1 164 VAL 164 164 164 VAL VAL D . n 
D 1 165 PHE 165 165 165 PHE PHE D . n 
D 1 166 GLY 166 166 166 GLY GLY D . n 
D 1 167 ASP 167 167 167 ASP ASP D . n 
D 1 168 ASP 168 168 168 ASP ASP D . n 
D 1 169 THR 169 169 169 THR THR D . n 
D 1 170 ILE 170 170 170 ILE ILE D . n 
D 1 171 ARG 171 171 171 ARG ARG D . n 
D 1 172 PHE 172 172 172 PHE PHE D . n 
D 1 173 ILE 173 173 173 ILE ILE D . n 
D 1 174 PHE 174 174 174 PHE PHE D . n 
D 1 175 THR 175 175 175 THR THR D . n 
D 1 176 PRO 176 176 176 PRO PRO D . n 
D 1 177 GLY 177 177 177 GLY GLY D . n 
D 1 178 HIS 178 178 178 HIS HIS D . n 
D 1 179 ALA 179 179 179 ALA ALA D . n 
D 1 180 PRO 180 180 180 PRO PRO D . n 
D 1 181 GLY 181 181 181 GLY GLY D . n 
D 1 182 HIS 182 182 182 HIS HIS D . n 
D 1 183 SER 183 183 183 SER SER D . n 
D 1 184 SER 184 184 184 SER SER D . n 
D 1 185 PHE 185 185 185 PHE PHE D . n 
D 1 186 LEU 186 186 186 LEU LEU D . n 
D 1 187 LEU 187 187 187 LEU LEU D . n 
D 1 188 ARG 188 188 188 ARG ARG D . n 
D 1 189 LEU 189 189 189 LEU LEU D . n 
D 1 190 PRO 190 190 190 PRO PRO D . n 
D 1 191 GLU 191 191 191 GLU GLU D . n 
D 1 192 THR 192 192 192 THR THR D . n 
D 1 193 GLY 193 193 193 GLY GLY D . n 
D 1 194 PRO 194 194 194 PRO PRO D . n 
D 1 195 VAL 195 195 195 VAL VAL D . n 
D 1 196 LEU 196 196 196 LEU LEU D . n 
D 1 197 LEU 197 197 197 LEU LEU D . n 
D 1 198 ALA 198 198 198 ALA ALA D . n 
D 1 199 VAL 199 199 199 VAL VAL D . n 
D 1 200 ASP 200 200 200 ASP ASP D . n 
D 1 201 ALA 201 201 201 ALA ALA D . n 
D 1 202 ALA 202 202 202 ALA ALA D . n 
D 1 203 TYR 203 203 203 TYR TYR D . n 
D 1 204 THR 204 204 204 THR THR D . n 
D 1 205 THR 205 205 205 THR THR D . n 
D 1 206 ASP 206 206 206 ASP ASP D . n 
D 1 207 HIS 207 207 207 HIS HIS D . n 
D 1 208 TRP 208 208 208 TRP TRP D . n 
D 1 209 ASP 209 209 209 ASP ASP D . n 
D 1 210 GLU 210 210 210 GLU GLU D . n 
D 1 211 LYS 211 211 211 LYS LYS D . n 
D 1 212 ALA 212 212 212 ALA ALA D . n 
D 1 213 LEU 213 213 213 LEU LEU D . n 
D 1 214 PRO 214 214 214 PRO PRO D . n 
D 1 215 GLY 215 215 215 GLY GLY D . n 
D 1 216 PHE 216 216 216 PHE PHE D . n 
D 1 217 LEU 217 217 217 LEU LEU D . n 
D 1 218 ALA 218 218 218 ALA ALA D . n 
D 1 219 SER 219 219 219 SER SER D . n 
D 1 220 THR 220 220 220 THR THR D . n 
D 1 221 VAL 221 221 221 VAL VAL D . n 
D 1 222 ASP 222 222 222 ASP ASP D . n 
D 1 223 ALA 223 223 223 ALA ALA D . n 
D 1 224 VAL 224 224 224 VAL VAL D . n 
D 1 225 ARG 225 225 225 ARG ARG D . n 
D 1 226 SER 226 226 226 SER SER D . n 
D 1 227 VAL 227 227 227 VAL VAL D . n 
D 1 228 ARG 228 228 228 ARG ARG D . n 
D 1 229 LYS 229 229 229 LYS LYS D . n 
D 1 230 LEU 230 230 230 LEU LEU D . n 
D 1 231 HIS 231 231 231 HIS HIS D . n 
D 1 232 ALA 232 232 232 ALA ALA D . n 
D 1 233 LEU 233 233 233 LEU LEU D . n 
D 1 234 ALA 234 234 234 ALA ALA D . n 
D 1 235 GLU 235 235 235 GLU GLU D . n 
D 1 236 LYS 236 236 236 LYS LYS D . n 
D 1 237 THR 237 237 237 THR THR D . n 
D 1 238 GLY 238 238 238 GLY GLY D . n 
D 1 239 ALA 239 239 239 ALA ALA D . n 
D 1 240 LEU 240 240 240 LEU LEU D . n 
D 1 241 VAL 241 241 241 VAL VAL D . n 
D 1 242 VAL 242 242 242 VAL VAL D . n 
D 1 243 TYR 243 243 243 TYR TYR D . n 
D 1 244 GLY 244 244 244 GLY GLY D . n 
D 1 245 HIS 245 245 245 HIS HIS D . n 
D 1 246 ASP 246 246 246 ASP ASP D . n 
D 1 247 PRO 247 247 247 PRO PRO D . n 
D 1 248 GLU 248 248 248 GLU GLU D . n 
D 1 249 ALA 249 249 249 ALA ALA D . n 
D 1 250 TRP 250 250 250 TRP TRP D . n 
D 1 251 PRO 251 251 251 PRO PRO D . n 
D 1 252 THR 252 252 252 THR THR D . n 
D 1 253 PHE 253 253 253 PHE PHE D . n 
D 1 254 ARG 254 254 254 ARG ARG D . n 
D 1 255 LEU 255 255 255 LEU LEU D . n 
D 1 256 ALA 256 256 ?   ?   ?   D . n 
D 1 257 PRO 257 257 ?   ?   ?   D . n 
D 1 258 GLU 258 258 ?   ?   ?   D . n 
D 1 259 TYR 259 259 ?   ?   ?   D . n 
D 1 260 TYR 260 260 ?   ?   ?   D . n 
D 1 261 ALA 261 261 ?   ?   ?   D . n 
E 1 1   MET 1   1   ?   ?   ?   E . n 
E 1 2   ALA 2   2   ?   ?   ?   E . n 
E 1 3   ALA 3   3   ?   ?   ?   E . n 
E 1 4   PRO 4   4   4   PRO PRO E . n 
E 1 5   ARG 5   5   5   ARG ARG E . n 
E 1 6   LEU 6   6   6   LEU LEU E . n 
E 1 7   TYR 7   7   7   TYR TYR E . n 
E 1 8   MET 8   8   8   MET MET E . n 
E 1 9   PHE 9   9   9   PHE PHE E . n 
E 1 10  GLN 10  10  10  GLN GLN E . n 
E 1 11  THR 11  11  11  THR THR E . n 
E 1 12  GLY 12  12  12  GLY GLY E . n 
E 1 13  THR 13  13  13  THR THR E . n 
E 1 14  LEU 14  14  14  LEU LEU E . n 
E 1 15  LYS 15  15  15  LYS LYS E . n 
E 1 16  CYS 16  16  16  CYS CYS E . n 
E 1 17  ARG 17  17  17  ARG ARG E . n 
E 1 18  VAL 18  18  18  VAL VAL E . n 
E 1 19  CYS 19  19  19  CYS CYS E . n 
E 1 20  ASN 20  20  20  ASN ASN E . n 
E 1 21  ILE 21  21  21  ILE ILE E . n 
E 1 22  LYS 22  22  22  LYS LYS E . n 
E 1 23  MET 23  23  23  MET MET E . n 
E 1 24  ASN 24  24  24  ASN ASN E . n 
E 1 25  ALA 25  25  25  ALA ALA E . n 
E 1 26  GLY 26  26  26  GLY GLY E . n 
E 1 27  LEU 27  27  27  LEU LEU E . n 
E 1 28  ASP 28  28  28  ASP ASP E . n 
E 1 29  ASP 29  29  29  ASP ASP E . n 
E 1 30  TYR 30  30  30  TYR TYR E . n 
E 1 31  GLU 31  31  31  GLU GLU E . n 
E 1 32  ILE 32  32  32  ILE ILE E . n 
E 1 33  PRO 33  33  33  PRO PRO E . n 
E 1 34  VAL 34  34  34  VAL VAL E . n 
E 1 35  PRO 35  35  35  PRO PRO E . n 
E 1 36  TRP 36  36  36  TRP TRP E . n 
E 1 37  TYR 37  37  37  TYR TYR E . n 
E 1 38  LEU 38  38  38  LEU LEU E . n 
E 1 39  ILE 39  39  39  ILE ILE E . n 
E 1 40  THR 40  40  40  THR THR E . n 
E 1 41  HIS 41  41  41  HIS HIS E . n 
E 1 42  PRO 42  42  42  PRO PRO E . n 
E 1 43  LYS 43  43  43  LYS LYS E . n 
E 1 44  GLY 44  44  44  GLY GLY E . n 
E 1 45  ASN 45  45  45  ASN ASN E . n 
E 1 46  VAL 46  46  46  VAL VAL E . n 
E 1 47  VAL 47  47  47  VAL VAL E . n 
E 1 48  ILE 48  48  48  ILE ILE E . n 
E 1 49  ASP 49  49  49  ASP ASP E . n 
E 1 50  GLY 50  50  50  GLY GLY E . n 
E 1 51  GLY 51  51  51  GLY GLY E . n 
E 1 52  CYS 52  52  52  CYS CYS E . n 
E 1 53  ALA 53  53  53  ALA ALA E . n 
E 1 54  VAL 54  54  54  VAL VAL E . n 
E 1 55  GLU 55  55  55  GLU GLU E . n 
E 1 56  CYS 56  56  56  CYS CYS E . n 
E 1 57  ALA 57  57  57  ALA ALA E . n 
E 1 58  SER 58  58  58  SER SER E . n 
E 1 59  ASP 59  59  59  ASP ASP E . n 
E 1 60  PRO 60  60  60  PRO PRO E . n 
E 1 61  LYS 61  61  61  LYS LYS E . n 
E 1 62  GLY 62  62  62  GLY GLY E . n 
E 1 63  TYR 63  63  63  TYR TYR E . n 
E 1 64  TRP 64  64  64  TRP TRP E . n 
E 1 65  GLY 65  65  65  GLY GLY E . n 
E 1 66  ASP 66  66  66  ASP ASP E . n 
E 1 67  ILE 67  67  67  ILE ILE E . n 
E 1 68  THR 68  68  68  THR THR E . n 
E 1 69  SER 69  69  69  SER SER E . n 
E 1 70  VAL 70  70  70  VAL VAL E . n 
E 1 71  TYR 71  71  71  TYR TYR E . n 
E 1 72  TRP 72  72  72  TRP TRP E . n 
E 1 73  PRO 73  73  73  PRO PRO E . n 
E 1 74  VAL 74  74  74  VAL VAL E . n 
E 1 75  MET 75  75  75  MET MET E . n 
E 1 76  ARG 76  76  76  ARG ARG E . n 
E 1 77  ILE 77  77  77  ILE ILE E . n 
E 1 78  GLU 78  78  78  GLU GLU E . n 
E 1 79  GLU 79  79  79  GLU GLU E . n 
E 1 80  GLY 80  80  80  GLY GLY E . n 
E 1 81  CYS 81  81  81  CYS CYS E . n 
E 1 82  VAL 82  82  82  VAL VAL E . n 
E 1 83  GLN 83  83  83  GLN GLN E . n 
E 1 84  ALA 84  84  84  ALA ALA E . n 
E 1 85  LEU 85  85  85  LEU LEU E . n 
E 1 86  LYS 86  86  86  LYS LYS E . n 
E 1 87  ALA 87  87  87  ALA ALA E . n 
E 1 88  PHE 88  88  88  PHE PHE E . n 
E 1 89  GLY 89  89  89  GLY GLY E . n 
E 1 90  ILE 90  90  90  ILE ILE E . n 
E 1 91  GLU 91  91  91  GLU GLU E . n 
E 1 92  PRO 92  92  92  PRO PRO E . n 
E 1 93  ALA 93  93  93  ALA ALA E . n 
E 1 94  ASP 94  94  94  ASP ASP E . n 
E 1 95  VAL 95  95  95  VAL VAL E . n 
E 1 96  ARG 96  96  96  ARG ARG E . n 
E 1 97  TYR 97  97  97  TYR TYR E . n 
E 1 98  VAL 98  98  98  VAL VAL E . n 
E 1 99  LEU 99  99  99  LEU LEU E . n 
E 1 100 HIS 100 100 100 HIS HIS E . n 
E 1 101 SER 101 101 101 SER SER E . n 
E 1 102 HIS 102 102 102 HIS HIS E . n 
E 1 103 LEU 103 103 103 LEU LEU E . n 
E 1 104 HIS 104 104 104 HIS HIS E . n 
E 1 105 LEU 105 105 105 LEU LEU E . n 
E 1 106 ASP 106 106 106 ASP ASP E . n 
E 1 107 HIS 107 107 107 HIS HIS E . n 
E 1 108 THR 108 108 108 THR THR E . n 
E 1 109 GLY 109 109 109 GLY GLY E . n 
E 1 110 ALA 110 110 110 ALA ALA E . n 
E 1 111 THR 111 111 111 THR THR E . n 
E 1 112 GLY 112 112 112 GLY GLY E . n 
E 1 113 ARG 113 113 113 ARG ARG E . n 
E 1 114 PHE 114 114 114 PHE PHE E . n 
E 1 115 PRO 115 115 115 PRO PRO E . n 
E 1 116 ASN 116 116 116 ASN ASN E . n 
E 1 117 ALA 117 117 117 ALA ALA E . n 
E 1 118 ILE 118 118 118 ILE ILE E . n 
E 1 119 HIS 119 119 119 HIS HIS E . n 
E 1 120 ILE 120 120 120 ILE ILE E . n 
E 1 121 VAL 121 121 121 VAL VAL E . n 
E 1 122 ARG 122 122 122 ARG ARG E . n 
E 1 123 ARG 123 123 123 ARG ARG E . n 
E 1 124 CYS 124 124 124 CYS CYS E . n 
E 1 125 GLU 125 125 125 GLU GLU E . n 
E 1 126 TYR 126 126 126 TYR TYR E . n 
E 1 127 GLU 127 127 127 GLU GLU E . n 
E 1 128 TYR 128 128 128 TYR TYR E . n 
E 1 129 ALA 129 129 129 ALA ALA E . n 
E 1 130 MET 130 130 130 MET MET E . n 
E 1 131 ALA 131 131 131 ALA ALA E . n 
E 1 132 PRO 132 132 132 PRO PRO E . n 
E 1 133 ASP 133 133 133 ASP ASP E . n 
E 1 134 TRP 134 134 134 TRP TRP E . n 
E 1 135 PHE 135 135 135 PHE PHE E . n 
E 1 136 SER 136 136 136 SER SER E . n 
E 1 137 ALA 137 137 137 ALA ALA E . n 
E 1 138 GLY 138 138 138 GLY GLY E . n 
E 1 139 GLY 139 139 139 GLY GLY E . n 
E 1 140 TYR 140 140 140 TYR TYR E . n 
E 1 141 ILE 141 141 141 ILE ILE E . n 
E 1 142 ARG 142 142 142 ARG ARG E . n 
E 1 143 ALA 143 143 143 ALA ALA E . n 
E 1 144 ASP 144 144 144 ASP ASP E . n 
E 1 145 PHE 145 145 145 PHE PHE E . n 
E 1 146 ASP 146 146 146 ASP ASP E . n 
E 1 147 ARG 147 147 147 ARG ARG E . n 
E 1 148 PRO 148 148 148 PRO PRO E . n 
E 1 149 ASP 149 149 149 ASP ASP E . n 
E 1 150 VAL 150 150 150 VAL VAL E . n 
E 1 151 LYS 151 151 151 LYS LYS E . n 
E 1 152 TRP 152 152 152 TRP TRP E . n 
E 1 153 HIS 153 153 153 HIS HIS E . n 
E 1 154 LEU 154 154 154 LEU LEU E . n 
E 1 155 LEU 155 155 155 LEU LEU E . n 
E 1 156 GLU 156 156 156 GLU GLU E . n 
E 1 157 GLY 157 157 157 GLY GLY E . n 
E 1 158 HIS 158 158 158 HIS HIS E . n 
E 1 159 ASP 159 159 159 ASP ASP E . n 
E 1 160 ASP 160 160 160 ASP ASP E . n 
E 1 161 GLY 161 161 161 GLY GLY E . n 
E 1 162 TYR 162 162 162 TYR TYR E . n 
E 1 163 ASP 163 163 163 ASP ASP E . n 
E 1 164 VAL 164 164 164 VAL VAL E . n 
E 1 165 PHE 165 165 165 PHE PHE E . n 
E 1 166 GLY 166 166 166 GLY GLY E . n 
E 1 167 ASP 167 167 167 ASP ASP E . n 
E 1 168 ASP 168 168 168 ASP ASP E . n 
E 1 169 THR 169 169 169 THR THR E . n 
E 1 170 ILE 170 170 170 ILE ILE E . n 
E 1 171 ARG 171 171 171 ARG ARG E . n 
E 1 172 PHE 172 172 172 PHE PHE E . n 
E 1 173 ILE 173 173 173 ILE ILE E . n 
E 1 174 PHE 174 174 174 PHE PHE E . n 
E 1 175 THR 175 175 175 THR THR E . n 
E 1 176 PRO 176 176 176 PRO PRO E . n 
E 1 177 GLY 177 177 177 GLY GLY E . n 
E 1 178 HIS 178 178 178 HIS HIS E . n 
E 1 179 ALA 179 179 179 ALA ALA E . n 
E 1 180 PRO 180 180 180 PRO PRO E . n 
E 1 181 GLY 181 181 181 GLY GLY E . n 
E 1 182 HIS 182 182 182 HIS HIS E . n 
E 1 183 SER 183 183 183 SER SER E . n 
E 1 184 SER 184 184 184 SER SER E . n 
E 1 185 PHE 185 185 185 PHE PHE E . n 
E 1 186 LEU 186 186 186 LEU LEU E . n 
E 1 187 LEU 187 187 187 LEU LEU E . n 
E 1 188 ARG 188 188 188 ARG ARG E . n 
E 1 189 LEU 189 189 189 LEU LEU E . n 
E 1 190 PRO 190 190 190 PRO PRO E . n 
E 1 191 GLU 191 191 191 GLU GLU E . n 
E 1 192 THR 192 192 192 THR THR E . n 
E 1 193 GLY 193 193 193 GLY GLY E . n 
E 1 194 PRO 194 194 194 PRO PRO E . n 
E 1 195 VAL 195 195 195 VAL VAL E . n 
E 1 196 LEU 196 196 196 LEU LEU E . n 
E 1 197 LEU 197 197 197 LEU LEU E . n 
E 1 198 ALA 198 198 198 ALA ALA E . n 
E 1 199 VAL 199 199 199 VAL VAL E . n 
E 1 200 ASP 200 200 200 ASP ASP E . n 
E 1 201 ALA 201 201 201 ALA ALA E . n 
E 1 202 ALA 202 202 202 ALA ALA E . n 
E 1 203 TYR 203 203 203 TYR TYR E . n 
E 1 204 THR 204 204 204 THR THR E . n 
E 1 205 THR 205 205 205 THR THR E . n 
E 1 206 ASP 206 206 206 ASP ASP E . n 
E 1 207 HIS 207 207 207 HIS HIS E . n 
E 1 208 TRP 208 208 208 TRP TRP E . n 
E 1 209 ASP 209 209 209 ASP ASP E . n 
E 1 210 GLU 210 210 210 GLU GLU E . n 
E 1 211 LYS 211 211 211 LYS LYS E . n 
E 1 212 ALA 212 212 212 ALA ALA E . n 
E 1 213 LEU 213 213 213 LEU LEU E . n 
E 1 214 PRO 214 214 214 PRO PRO E . n 
E 1 215 GLY 215 215 215 GLY GLY E . n 
E 1 216 PHE 216 216 216 PHE PHE E . n 
E 1 217 LEU 217 217 217 LEU LEU E . n 
E 1 218 ALA 218 218 218 ALA ALA E . n 
E 1 219 SER 219 219 219 SER SER E . n 
E 1 220 THR 220 220 220 THR THR E . n 
E 1 221 VAL 221 221 221 VAL VAL E . n 
E 1 222 ASP 222 222 222 ASP ASP E . n 
E 1 223 ALA 223 223 223 ALA ALA E . n 
E 1 224 VAL 224 224 224 VAL VAL E . n 
E 1 225 ARG 225 225 225 ARG ARG E . n 
E 1 226 SER 226 226 226 SER SER E . n 
E 1 227 VAL 227 227 227 VAL VAL E . n 
E 1 228 ARG 228 228 228 ARG ARG E . n 
E 1 229 LYS 229 229 229 LYS LYS E . n 
E 1 230 LEU 230 230 230 LEU LEU E . n 
E 1 231 HIS 231 231 231 HIS HIS E . n 
E 1 232 ALA 232 232 232 ALA ALA E . n 
E 1 233 LEU 233 233 233 LEU LEU E . n 
E 1 234 ALA 234 234 234 ALA ALA E . n 
E 1 235 GLU 235 235 235 GLU GLU E . n 
E 1 236 LYS 236 236 236 LYS LYS E . n 
E 1 237 THR 237 237 237 THR THR E . n 
E 1 238 GLY 238 238 238 GLY GLY E . n 
E 1 239 ALA 239 239 239 ALA ALA E . n 
E 1 240 LEU 240 240 240 LEU LEU E . n 
E 1 241 VAL 241 241 241 VAL VAL E . n 
E 1 242 VAL 242 242 242 VAL VAL E . n 
E 1 243 TYR 243 243 243 TYR TYR E . n 
E 1 244 GLY 244 244 244 GLY GLY E . n 
E 1 245 HIS 245 245 245 HIS HIS E . n 
E 1 246 ASP 246 246 246 ASP ASP E . n 
E 1 247 PRO 247 247 247 PRO PRO E . n 
E 1 248 GLU 248 248 248 GLU GLU E . n 
E 1 249 ALA 249 249 249 ALA ALA E . n 
E 1 250 TRP 250 250 250 TRP TRP E . n 
E 1 251 PRO 251 251 251 PRO PRO E . n 
E 1 252 THR 252 252 252 THR THR E . n 
E 1 253 PHE 253 253 253 PHE PHE E . n 
E 1 254 ARG 254 254 254 ARG ARG E . n 
E 1 255 LEU 255 255 255 LEU LEU E . n 
E 1 256 ALA 256 256 ?   ?   ?   E . n 
E 1 257 PRO 257 257 ?   ?   ?   E . n 
E 1 258 GLU 258 258 ?   ?   ?   E . n 
E 1 259 TYR 259 259 ?   ?   ?   E . n 
E 1 260 TYR 260 260 ?   ?   ?   E . n 
E 1 261 ALA 261 261 ?   ?   ?   E . n 
F 1 1   MET 1   1   ?   ?   ?   F . n 
F 1 2   ALA 2   2   ?   ?   ?   F . n 
F 1 3   ALA 3   3   3   ALA ALA F . n 
F 1 4   PRO 4   4   4   PRO PRO F . n 
F 1 5   ARG 5   5   5   ARG ARG F . n 
F 1 6   LEU 6   6   6   LEU LEU F . n 
F 1 7   TYR 7   7   7   TYR TYR F . n 
F 1 8   MET 8   8   8   MET MET F . n 
F 1 9   PHE 9   9   9   PHE PHE F . n 
F 1 10  GLN 10  10  10  GLN GLN F . n 
F 1 11  THR 11  11  11  THR THR F . n 
F 1 12  GLY 12  12  12  GLY GLY F . n 
F 1 13  THR 13  13  13  THR THR F . n 
F 1 14  LEU 14  14  14  LEU LEU F . n 
F 1 15  LYS 15  15  15  LYS LYS F . n 
F 1 16  CYS 16  16  16  CYS CYS F . n 
F 1 17  ARG 17  17  17  ARG ARG F . n 
F 1 18  VAL 18  18  18  VAL VAL F . n 
F 1 19  CYS 19  19  19  CYS CYS F . n 
F 1 20  ASN 20  20  20  ASN ASN F . n 
F 1 21  ILE 21  21  21  ILE ILE F . n 
F 1 22  LYS 22  22  22  LYS LYS F . n 
F 1 23  MET 23  23  23  MET MET F . n 
F 1 24  ASN 24  24  24  ASN ASN F . n 
F 1 25  ALA 25  25  25  ALA ALA F . n 
F 1 26  GLY 26  26  26  GLY GLY F . n 
F 1 27  LEU 27  27  27  LEU LEU F . n 
F 1 28  ASP 28  28  28  ASP ASP F . n 
F 1 29  ASP 29  29  29  ASP ASP F . n 
F 1 30  TYR 30  30  30  TYR TYR F . n 
F 1 31  GLU 31  31  31  GLU GLU F . n 
F 1 32  ILE 32  32  32  ILE ILE F . n 
F 1 33  PRO 33  33  33  PRO PRO F . n 
F 1 34  VAL 34  34  34  VAL VAL F . n 
F 1 35  PRO 35  35  35  PRO PRO F . n 
F 1 36  TRP 36  36  36  TRP TRP F . n 
F 1 37  TYR 37  37  37  TYR TYR F . n 
F 1 38  LEU 38  38  38  LEU LEU F . n 
F 1 39  ILE 39  39  39  ILE ILE F . n 
F 1 40  THR 40  40  40  THR THR F . n 
F 1 41  HIS 41  41  41  HIS HIS F . n 
F 1 42  PRO 42  42  42  PRO PRO F . n 
F 1 43  LYS 43  43  43  LYS LYS F . n 
F 1 44  GLY 44  44  44  GLY GLY F . n 
F 1 45  ASN 45  45  45  ASN ASN F . n 
F 1 46  VAL 46  46  46  VAL VAL F . n 
F 1 47  VAL 47  47  47  VAL VAL F . n 
F 1 48  ILE 48  48  48  ILE ILE F . n 
F 1 49  ASP 49  49  49  ASP ASP F . n 
F 1 50  GLY 50  50  50  GLY GLY F . n 
F 1 51  GLY 51  51  51  GLY GLY F . n 
F 1 52  CYS 52  52  52  CYS CYS F . n 
F 1 53  ALA 53  53  53  ALA ALA F . n 
F 1 54  VAL 54  54  54  VAL VAL F . n 
F 1 55  GLU 55  55  55  GLU GLU F . n 
F 1 56  CYS 56  56  56  CYS CYS F . n 
F 1 57  ALA 57  57  57  ALA ALA F . n 
F 1 58  SER 58  58  58  SER SER F . n 
F 1 59  ASP 59  59  59  ASP ASP F . n 
F 1 60  PRO 60  60  60  PRO PRO F . n 
F 1 61  LYS 61  61  61  LYS LYS F . n 
F 1 62  GLY 62  62  62  GLY GLY F . n 
F 1 63  TYR 63  63  63  TYR TYR F . n 
F 1 64  TRP 64  64  64  TRP TRP F . n 
F 1 65  GLY 65  65  65  GLY GLY F . n 
F 1 66  ASP 66  66  66  ASP ASP F . n 
F 1 67  ILE 67  67  67  ILE ILE F . n 
F 1 68  THR 68  68  68  THR THR F . n 
F 1 69  SER 69  69  69  SER SER F . n 
F 1 70  VAL 70  70  70  VAL VAL F . n 
F 1 71  TYR 71  71  71  TYR TYR F . n 
F 1 72  TRP 72  72  72  TRP TRP F . n 
F 1 73  PRO 73  73  73  PRO PRO F . n 
F 1 74  VAL 74  74  74  VAL VAL F . n 
F 1 75  MET 75  75  75  MET MET F . n 
F 1 76  ARG 76  76  76  ARG ARG F . n 
F 1 77  ILE 77  77  77  ILE ILE F . n 
F 1 78  GLU 78  78  78  GLU GLU F . n 
F 1 79  GLU 79  79  79  GLU GLU F . n 
F 1 80  GLY 80  80  80  GLY GLY F . n 
F 1 81  CYS 81  81  81  CYS CYS F . n 
F 1 82  VAL 82  82  82  VAL VAL F . n 
F 1 83  GLN 83  83  83  GLN GLN F . n 
F 1 84  ALA 84  84  84  ALA ALA F . n 
F 1 85  LEU 85  85  85  LEU LEU F . n 
F 1 86  LYS 86  86  86  LYS LYS F . n 
F 1 87  ALA 87  87  87  ALA ALA F . n 
F 1 88  PHE 88  88  88  PHE PHE F . n 
F 1 89  GLY 89  89  89  GLY GLY F . n 
F 1 90  ILE 90  90  90  ILE ILE F . n 
F 1 91  GLU 91  91  91  GLU GLU F . n 
F 1 92  PRO 92  92  92  PRO PRO F . n 
F 1 93  ALA 93  93  93  ALA ALA F . n 
F 1 94  ASP 94  94  94  ASP ASP F . n 
F 1 95  VAL 95  95  95  VAL VAL F . n 
F 1 96  ARG 96  96  96  ARG ARG F . n 
F 1 97  TYR 97  97  97  TYR TYR F . n 
F 1 98  VAL 98  98  98  VAL VAL F . n 
F 1 99  LEU 99  99  99  LEU LEU F . n 
F 1 100 HIS 100 100 100 HIS HIS F . n 
F 1 101 SER 101 101 101 SER SER F . n 
F 1 102 HIS 102 102 102 HIS HIS F . n 
F 1 103 LEU 103 103 103 LEU LEU F . n 
F 1 104 HIS 104 104 104 HIS HIS F . n 
F 1 105 LEU 105 105 105 LEU LEU F . n 
F 1 106 ASP 106 106 106 ASP ASP F . n 
F 1 107 HIS 107 107 107 HIS HIS F . n 
F 1 108 THR 108 108 108 THR THR F . n 
F 1 109 GLY 109 109 109 GLY GLY F . n 
F 1 110 ALA 110 110 110 ALA ALA F . n 
F 1 111 THR 111 111 111 THR THR F . n 
F 1 112 GLY 112 112 112 GLY GLY F . n 
F 1 113 ARG 113 113 113 ARG ARG F . n 
F 1 114 PHE 114 114 114 PHE PHE F . n 
F 1 115 PRO 115 115 115 PRO PRO F . n 
F 1 116 ASN 116 116 116 ASN ASN F . n 
F 1 117 ALA 117 117 117 ALA ALA F . n 
F 1 118 ILE 118 118 118 ILE ILE F . n 
F 1 119 HIS 119 119 119 HIS HIS F . n 
F 1 120 ILE 120 120 120 ILE ILE F . n 
F 1 121 VAL 121 121 121 VAL VAL F . n 
F 1 122 ARG 122 122 122 ARG ARG F . n 
F 1 123 ARG 123 123 123 ARG ARG F . n 
F 1 124 CYS 124 124 124 CYS CYS F . n 
F 1 125 GLU 125 125 125 GLU GLU F . n 
F 1 126 TYR 126 126 126 TYR TYR F . n 
F 1 127 GLU 127 127 127 GLU GLU F . n 
F 1 128 TYR 128 128 128 TYR TYR F . n 
F 1 129 ALA 129 129 129 ALA ALA F . n 
F 1 130 MET 130 130 130 MET MET F . n 
F 1 131 ALA 131 131 131 ALA ALA F . n 
F 1 132 PRO 132 132 132 PRO PRO F . n 
F 1 133 ASP 133 133 133 ASP ASP F . n 
F 1 134 TRP 134 134 134 TRP TRP F . n 
F 1 135 PHE 135 135 135 PHE PHE F . n 
F 1 136 SER 136 136 136 SER SER F . n 
F 1 137 ALA 137 137 137 ALA ALA F . n 
F 1 138 GLY 138 138 138 GLY GLY F . n 
F 1 139 GLY 139 139 139 GLY GLY F . n 
F 1 140 TYR 140 140 140 TYR TYR F . n 
F 1 141 ILE 141 141 141 ILE ILE F . n 
F 1 142 ARG 142 142 142 ARG ARG F . n 
F 1 143 ALA 143 143 143 ALA ALA F . n 
F 1 144 ASP 144 144 144 ASP ASP F . n 
F 1 145 PHE 145 145 145 PHE PHE F . n 
F 1 146 ASP 146 146 146 ASP ASP F . n 
F 1 147 ARG 147 147 147 ARG ARG F . n 
F 1 148 PRO 148 148 148 PRO PRO F . n 
F 1 149 ASP 149 149 149 ASP ASP F . n 
F 1 150 VAL 150 150 150 VAL VAL F . n 
F 1 151 LYS 151 151 151 LYS LYS F . n 
F 1 152 TRP 152 152 152 TRP TRP F . n 
F 1 153 HIS 153 153 153 HIS HIS F . n 
F 1 154 LEU 154 154 154 LEU LEU F . n 
F 1 155 LEU 155 155 155 LEU LEU F . n 
F 1 156 GLU 156 156 156 GLU GLU F . n 
F 1 157 GLY 157 157 157 GLY GLY F . n 
F 1 158 HIS 158 158 158 HIS HIS F . n 
F 1 159 ASP 159 159 159 ASP ASP F . n 
F 1 160 ASP 160 160 160 ASP ASP F . n 
F 1 161 GLY 161 161 161 GLY GLY F . n 
F 1 162 TYR 162 162 162 TYR TYR F . n 
F 1 163 ASP 163 163 163 ASP ASP F . n 
F 1 164 VAL 164 164 164 VAL VAL F . n 
F 1 165 PHE 165 165 165 PHE PHE F . n 
F 1 166 GLY 166 166 166 GLY GLY F . n 
F 1 167 ASP 167 167 167 ASP ASP F . n 
F 1 168 ASP 168 168 168 ASP ASP F . n 
F 1 169 THR 169 169 169 THR THR F . n 
F 1 170 ILE 170 170 170 ILE ILE F . n 
F 1 171 ARG 171 171 171 ARG ARG F . n 
F 1 172 PHE 172 172 172 PHE PHE F . n 
F 1 173 ILE 173 173 173 ILE ILE F . n 
F 1 174 PHE 174 174 174 PHE PHE F . n 
F 1 175 THR 175 175 175 THR THR F . n 
F 1 176 PRO 176 176 176 PRO PRO F . n 
F 1 177 GLY 177 177 177 GLY GLY F . n 
F 1 178 HIS 178 178 178 HIS HIS F . n 
F 1 179 ALA 179 179 179 ALA ALA F . n 
F 1 180 PRO 180 180 180 PRO PRO F . n 
F 1 181 GLY 181 181 181 GLY GLY F . n 
F 1 182 HIS 182 182 182 HIS HIS F . n 
F 1 183 SER 183 183 183 SER SER F . n 
F 1 184 SER 184 184 184 SER SER F . n 
F 1 185 PHE 185 185 185 PHE PHE F . n 
F 1 186 LEU 186 186 186 LEU LEU F . n 
F 1 187 LEU 187 187 187 LEU LEU F . n 
F 1 188 ARG 188 188 188 ARG ARG F . n 
F 1 189 LEU 189 189 189 LEU LEU F . n 
F 1 190 PRO 190 190 190 PRO PRO F . n 
F 1 191 GLU 191 191 191 GLU GLU F . n 
F 1 192 THR 192 192 192 THR THR F . n 
F 1 193 GLY 193 193 193 GLY GLY F . n 
F 1 194 PRO 194 194 194 PRO PRO F . n 
F 1 195 VAL 195 195 195 VAL VAL F . n 
F 1 196 LEU 196 196 196 LEU LEU F . n 
F 1 197 LEU 197 197 197 LEU LEU F . n 
F 1 198 ALA 198 198 198 ALA ALA F . n 
F 1 199 VAL 199 199 199 VAL VAL F . n 
F 1 200 ASP 200 200 200 ASP ASP F . n 
F 1 201 ALA 201 201 201 ALA ALA F . n 
F 1 202 ALA 202 202 202 ALA ALA F . n 
F 1 203 TYR 203 203 203 TYR TYR F . n 
F 1 204 THR 204 204 204 THR THR F . n 
F 1 205 THR 205 205 205 THR THR F . n 
F 1 206 ASP 206 206 206 ASP ASP F . n 
F 1 207 HIS 207 207 207 HIS HIS F . n 
F 1 208 TRP 208 208 208 TRP TRP F . n 
F 1 209 ASP 209 209 209 ASP ASP F . n 
F 1 210 GLU 210 210 210 GLU GLU F . n 
F 1 211 LYS 211 211 211 LYS LYS F . n 
F 1 212 ALA 212 212 212 ALA ALA F . n 
F 1 213 LEU 213 213 213 LEU LEU F . n 
F 1 214 PRO 214 214 214 PRO PRO F . n 
F 1 215 GLY 215 215 215 GLY GLY F . n 
F 1 216 PHE 216 216 216 PHE PHE F . n 
F 1 217 LEU 217 217 217 LEU LEU F . n 
F 1 218 ALA 218 218 218 ALA ALA F . n 
F 1 219 SER 219 219 219 SER SER F . n 
F 1 220 THR 220 220 220 THR THR F . n 
F 1 221 VAL 221 221 221 VAL VAL F . n 
F 1 222 ASP 222 222 222 ASP ASP F . n 
F 1 223 ALA 223 223 223 ALA ALA F . n 
F 1 224 VAL 224 224 224 VAL VAL F . n 
F 1 225 ARG 225 225 225 ARG ARG F . n 
F 1 226 SER 226 226 226 SER SER F . n 
F 1 227 VAL 227 227 227 VAL VAL F . n 
F 1 228 ARG 228 228 228 ARG ARG F . n 
F 1 229 LYS 229 229 229 LYS LYS F . n 
F 1 230 LEU 230 230 230 LEU LEU F . n 
F 1 231 HIS 231 231 231 HIS HIS F . n 
F 1 232 ALA 232 232 232 ALA ALA F . n 
F 1 233 LEU 233 233 233 LEU LEU F . n 
F 1 234 ALA 234 234 234 ALA ALA F . n 
F 1 235 GLU 235 235 235 GLU GLU F . n 
F 1 236 LYS 236 236 236 LYS LYS F . n 
F 1 237 THR 237 237 237 THR THR F . n 
F 1 238 GLY 238 238 238 GLY GLY F . n 
F 1 239 ALA 239 239 239 ALA ALA F . n 
F 1 240 LEU 240 240 240 LEU LEU F . n 
F 1 241 VAL 241 241 241 VAL VAL F . n 
F 1 242 VAL 242 242 242 VAL VAL F . n 
F 1 243 TYR 243 243 243 TYR TYR F . n 
F 1 244 GLY 244 244 244 GLY GLY F . n 
F 1 245 HIS 245 245 245 HIS HIS F . n 
F 1 246 ASP 246 246 246 ASP ASP F . n 
F 1 247 PRO 247 247 247 PRO PRO F . n 
F 1 248 GLU 248 248 248 GLU GLU F . n 
F 1 249 ALA 249 249 249 ALA ALA F . n 
F 1 250 TRP 250 250 250 TRP TRP F . n 
F 1 251 PRO 251 251 251 PRO PRO F . n 
F 1 252 THR 252 252 252 THR THR F . n 
F 1 253 PHE 253 253 253 PHE PHE F . n 
F 1 254 ARG 254 254 254 ARG ARG F . n 
F 1 255 LEU 255 255 ?   ?   ?   F . n 
F 1 256 ALA 256 256 ?   ?   ?   F . n 
F 1 257 PRO 257 257 ?   ?   ?   F . n 
F 1 258 GLU 258 258 ?   ?   ?   F . n 
F 1 259 TYR 259 259 ?   ?   ?   F . n 
F 1 260 TYR 260 260 ?   ?   ?   F . n 
F 1 261 ALA 261 261 ?   ?   ?   F . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        NI 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   NI 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
G 2 NI  1   301 262  NI  NI  A . 
H 2 NI  1   302 263  NI  NI  A . 
I 2 NI  1   301 262  NI  NI  B . 
J 2 NI  1   302 263  NI  NI  B . 
K 2 NI  1   301 262  NI  NI  C . 
L 2 NI  1   302 263  NI  NI  C . 
M 2 NI  1   301 262  NI  NI  D . 
N 2 NI  1   302 263  NI  NI  D . 
O 2 NI  1   301 262  NI  NI  E . 
P 2 NI  1   302 263  NI  NI  E . 
Q 2 NI  1   301 262  NI  NI  F . 
R 2 NI  1   302 263  NI  NI  F . 
S 3 HOH 1   401 694  HOH HOH A . 
S 3 HOH 2   402 444  HOH HOH A . 
S 3 HOH 3   403 31   HOH HOH A . 
S 3 HOH 4   404 419  HOH HOH A . 
S 3 HOH 5   405 926  HOH HOH A . 
S 3 HOH 6   406 262  HOH HOH A . 
S 3 HOH 7   407 23   HOH HOH A . 
S 3 HOH 8   408 286  HOH HOH A . 
S 3 HOH 9   409 960  HOH HOH A . 
S 3 HOH 10  410 377  HOH HOH A . 
S 3 HOH 11  411 154  HOH HOH A . 
S 3 HOH 12  412 730  HOH HOH A . 
S 3 HOH 13  413 459  HOH HOH A . 
S 3 HOH 14  414 583  HOH HOH A . 
S 3 HOH 15  415 246  HOH HOH A . 
S 3 HOH 16  416 228  HOH HOH A . 
S 3 HOH 17  417 932  HOH HOH A . 
S 3 HOH 18  418 57   HOH HOH A . 
S 3 HOH 19  419 183  HOH HOH A . 
S 3 HOH 20  420 461  HOH HOH A . 
S 3 HOH 21  421 12   HOH HOH A . 
S 3 HOH 22  422 398  HOH HOH A . 
S 3 HOH 23  423 76   HOH HOH A . 
S 3 HOH 24  424 467  HOH HOH A . 
S 3 HOH 25  425 716  HOH HOH A . 
S 3 HOH 26  426 72   HOH HOH A . 
S 3 HOH 27  427 64   HOH HOH A . 
S 3 HOH 28  428 423  HOH HOH A . 
S 3 HOH 29  429 346  HOH HOH A . 
S 3 HOH 30  430 280  HOH HOH A . 
S 3 HOH 31  431 134  HOH HOH A . 
S 3 HOH 32  432 311  HOH HOH A . 
S 3 HOH 33  433 351  HOH HOH A . 
S 3 HOH 34  434 826  HOH HOH A . 
S 3 HOH 35  435 50   HOH HOH A . 
S 3 HOH 36  436 523  HOH HOH A . 
S 3 HOH 37  437 69   HOH HOH A . 
S 3 HOH 38  438 26   HOH HOH A . 
S 3 HOH 39  439 1012 HOH HOH A . 
S 3 HOH 40  440 98   HOH HOH A . 
S 3 HOH 41  441 105  HOH HOH A . 
S 3 HOH 42  442 586  HOH HOH A . 
S 3 HOH 43  443 202  HOH HOH A . 
S 3 HOH 44  444 373  HOH HOH A . 
S 3 HOH 45  445 774  HOH HOH A . 
S 3 HOH 46  446 115  HOH HOH A . 
S 3 HOH 47  447 594  HOH HOH A . 
S 3 HOH 48  448 430  HOH HOH A . 
S 3 HOH 49  449 636  HOH HOH A . 
S 3 HOH 50  450 289  HOH HOH A . 
S 3 HOH 51  451 88   HOH HOH A . 
S 3 HOH 52  452 603  HOH HOH A . 
S 3 HOH 53  453 342  HOH HOH A . 
S 3 HOH 54  454 949  HOH HOH A . 
S 3 HOH 55  455 510  HOH HOH A . 
S 3 HOH 56  456 299  HOH HOH A . 
S 3 HOH 57  457 14   HOH HOH A . 
S 3 HOH 58  458 38   HOH HOH A . 
S 3 HOH 59  459 420  HOH HOH A . 
S 3 HOH 60  460 63   HOH HOH A . 
S 3 HOH 61  461 649  HOH HOH A . 
S 3 HOH 62  462 189  HOH HOH A . 
S 3 HOH 63  463 177  HOH HOH A . 
S 3 HOH 64  464 528  HOH HOH A . 
S 3 HOH 65  465 575  HOH HOH A . 
S 3 HOH 66  466 652  HOH HOH A . 
S 3 HOH 67  467 204  HOH HOH A . 
S 3 HOH 68  468 593  HOH HOH A . 
S 3 HOH 69  469 320  HOH HOH A . 
S 3 HOH 70  470 194  HOH HOH A . 
S 3 HOH 71  471 428  HOH HOH A . 
S 3 HOH 72  472 223  HOH HOH A . 
S 3 HOH 73  473 151  HOH HOH A . 
S 3 HOH 74  474 418  HOH HOH A . 
S 3 HOH 75  475 653  HOH HOH A . 
S 3 HOH 76  476 820  HOH HOH A . 
S 3 HOH 77  477 903  HOH HOH A . 
S 3 HOH 78  478 234  HOH HOH A . 
S 3 HOH 79  479 487  HOH HOH A . 
S 3 HOH 80  480 169  HOH HOH A . 
S 3 HOH 81  481 86   HOH HOH A . 
S 3 HOH 82  482 109  HOH HOH A . 
S 3 HOH 83  483 7    HOH HOH A . 
S 3 HOH 84  484 67   HOH HOH A . 
S 3 HOH 85  485 203  HOH HOH A . 
S 3 HOH 86  486 225  HOH HOH A . 
S 3 HOH 87  487 440  HOH HOH A . 
S 3 HOH 88  488 856  HOH HOH A . 
S 3 HOH 89  489 128  HOH HOH A . 
S 3 HOH 90  490 334  HOH HOH A . 
S 3 HOH 91  491 387  HOH HOH A . 
S 3 HOH 92  492 207  HOH HOH A . 
S 3 HOH 93  493 62   HOH HOH A . 
S 3 HOH 94  494 396  HOH HOH A . 
S 3 HOH 95  495 6    HOH HOH A . 
S 3 HOH 96  496 1014 HOH HOH A . 
S 3 HOH 97  497 285  HOH HOH A . 
S 3 HOH 98  498 81   HOH HOH A . 
S 3 HOH 99  499 956  HOH HOH A . 
S 3 HOH 100 500 715  HOH HOH A . 
S 3 HOH 101 501 174  HOH HOH A . 
S 3 HOH 102 502 291  HOH HOH A . 
S 3 HOH 103 503 24   HOH HOH A . 
S 3 HOH 104 504 147  HOH HOH A . 
S 3 HOH 105 505 208  HOH HOH A . 
S 3 HOH 106 506 65   HOH HOH A . 
S 3 HOH 107 507 879  HOH HOH A . 
S 3 HOH 108 508 412  HOH HOH A . 
S 3 HOH 109 509 384  HOH HOH A . 
S 3 HOH 110 510 846  HOH HOH A . 
S 3 HOH 111 511 554  HOH HOH A . 
S 3 HOH 112 512 328  HOH HOH A . 
S 3 HOH 113 513 630  HOH HOH A . 
S 3 HOH 114 514 705  HOH HOH A . 
S 3 HOH 115 515 674  HOH HOH A . 
S 3 HOH 116 516 933  HOH HOH A . 
S 3 HOH 117 517 1024 HOH HOH A . 
S 3 HOH 118 518 557  HOH HOH A . 
S 3 HOH 119 519 477  HOH HOH A . 
S 3 HOH 120 520 182  HOH HOH A . 
S 3 HOH 121 521 448  HOH HOH A . 
S 3 HOH 122 522 464  HOH HOH A . 
S 3 HOH 123 523 591  HOH HOH A . 
S 3 HOH 124 524 390  HOH HOH A . 
S 3 HOH 125 525 524  HOH HOH A . 
S 3 HOH 126 526 488  HOH HOH A . 
S 3 HOH 127 527 59   HOH HOH A . 
S 3 HOH 128 528 787  HOH HOH A . 
S 3 HOH 129 529 762  HOH HOH A . 
S 3 HOH 130 530 1061 HOH HOH A . 
S 3 HOH 131 531 972  HOH HOH A . 
S 3 HOH 132 532 910  HOH HOH A . 
S 3 HOH 133 533 432  HOH HOH A . 
S 3 HOH 134 534 951  HOH HOH A . 
S 3 HOH 135 535 620  HOH HOH A . 
S 3 HOH 136 536 348  HOH HOH A . 
S 3 HOH 137 537 885  HOH HOH A . 
S 3 HOH 138 538 39   HOH HOH A . 
S 3 HOH 139 539 282  HOH HOH A . 
S 3 HOH 140 540 421  HOH HOH A . 
S 3 HOH 141 541 654  HOH HOH A . 
S 3 HOH 142 542 697  HOH HOH A . 
S 3 HOH 143 543 888  HOH HOH A . 
S 3 HOH 144 544 544  HOH HOH A . 
S 3 HOH 145 545 1017 HOH HOH A . 
S 3 HOH 146 546 318  HOH HOH A . 
S 3 HOH 147 547 744  HOH HOH A . 
S 3 HOH 148 548 136  HOH HOH A . 
S 3 HOH 149 549 1069 HOH HOH A . 
S 3 HOH 150 550 723  HOH HOH A . 
S 3 HOH 151 551 717  HOH HOH A . 
S 3 HOH 152 552 897  HOH HOH A . 
S 3 HOH 153 553 819  HOH HOH A . 
S 3 HOH 154 554 486  HOH HOH A . 
S 3 HOH 155 555 130  HOH HOH A . 
S 3 HOH 156 556 911  HOH HOH A . 
S 3 HOH 157 557 852  HOH HOH A . 
S 3 HOH 158 558 670  HOH HOH A . 
S 3 HOH 159 559 883  HOH HOH A . 
S 3 HOH 160 560 1062 HOH HOH A . 
S 3 HOH 161 561 493  HOH HOH A . 
S 3 HOH 162 562 313  HOH HOH A . 
S 3 HOH 163 563 799  HOH HOH A . 
S 3 HOH 164 564 868  HOH HOH A . 
S 3 HOH 165 565 515  HOH HOH A . 
S 3 HOH 166 566 1031 HOH HOH A . 
S 3 HOH 167 567 734  HOH HOH A . 
S 3 HOH 168 568 936  HOH HOH A . 
S 3 HOH 169 569 413  HOH HOH A . 
S 3 HOH 170 570 615  HOH HOH A . 
S 3 HOH 171 571 719  HOH HOH A . 
S 3 HOH 172 572 912  HOH HOH A . 
S 3 HOH 173 573 867  HOH HOH A . 
S 3 HOH 174 574 731  HOH HOH A . 
S 3 HOH 175 575 905  HOH HOH A . 
S 3 HOH 176 576 525  HOH HOH A . 
S 3 HOH 177 577 496  HOH HOH A . 
S 3 HOH 178 578 252  HOH HOH A . 
S 3 HOH 179 579 966  HOH HOH A . 
S 3 HOH 180 580 735  HOH HOH A . 
S 3 HOH 181 581 576  HOH HOH A . 
S 3 HOH 182 582 942  HOH HOH A . 
S 3 HOH 183 583 944  HOH HOH A . 
S 3 HOH 184 584 829  HOH HOH A . 
S 3 HOH 185 585 631  HOH HOH A . 
S 3 HOH 186 586 850  HOH HOH A . 
T 3 HOH 1   401 475  HOH HOH B . 
T 3 HOH 2   402 899  HOH HOH B . 
T 3 HOH 3   403 1002 HOH HOH B . 
T 3 HOH 4   404 522  HOH HOH B . 
T 3 HOH 5   405 726  HOH HOH B . 
T 3 HOH 6   406 511  HOH HOH B . 
T 3 HOH 7   407 433  HOH HOH B . 
T 3 HOH 8   408 5    HOH HOH B . 
T 3 HOH 9   409 526  HOH HOH B . 
T 3 HOH 10  410 771  HOH HOH B . 
T 3 HOH 11  411 601  HOH HOH B . 
T 3 HOH 12  412 317  HOH HOH B . 
T 3 HOH 13  413 404  HOH HOH B . 
T 3 HOH 14  414 416  HOH HOH B . 
T 3 HOH 15  415 518  HOH HOH B . 
T 3 HOH 16  416 725  HOH HOH B . 
T 3 HOH 17  417 415  HOH HOH B . 
T 3 HOH 18  418 611  HOH HOH B . 
T 3 HOH 19  419 74   HOH HOH B . 
T 3 HOH 20  420 625  HOH HOH B . 
T 3 HOH 21  421 827  HOH HOH B . 
T 3 HOH 22  422 82   HOH HOH B . 
T 3 HOH 23  423 833  HOH HOH B . 
T 3 HOH 24  424 274  HOH HOH B . 
T 3 HOH 25  425 519  HOH HOH B . 
T 3 HOH 26  426 339  HOH HOH B . 
T 3 HOH 27  427 166  HOH HOH B . 
T 3 HOH 28  428 474  HOH HOH B . 
T 3 HOH 29  429 123  HOH HOH B . 
T 3 HOH 30  430 146  HOH HOH B . 
T 3 HOH 31  431 292  HOH HOH B . 
T 3 HOH 32  432 104  HOH HOH B . 
T 3 HOH 33  433 617  HOH HOH B . 
T 3 HOH 34  434 302  HOH HOH B . 
T 3 HOH 35  435 490  HOH HOH B . 
T 3 HOH 36  436 449  HOH HOH B . 
T 3 HOH 37  437 595  HOH HOH B . 
T 3 HOH 38  438 192  HOH HOH B . 
T 3 HOH 39  439 326  HOH HOH B . 
T 3 HOH 40  440 101  HOH HOH B . 
T 3 HOH 41  441 1008 HOH HOH B . 
T 3 HOH 42  442 648  HOH HOH B . 
T 3 HOH 43  443 211  HOH HOH B . 
T 3 HOH 44  444 145  HOH HOH B . 
T 3 HOH 45  445 561  HOH HOH B . 
T 3 HOH 46  446 1    HOH HOH B . 
T 3 HOH 47  447 244  HOH HOH B . 
T 3 HOH 48  448 80   HOH HOH B . 
T 3 HOH 49  449 19   HOH HOH B . 
T 3 HOH 50  450 540  HOH HOH B . 
T 3 HOH 51  451 808  HOH HOH B . 
T 3 HOH 52  452 410  HOH HOH B . 
T 3 HOH 53  453 456  HOH HOH B . 
T 3 HOH 54  454 61   HOH HOH B . 
T 3 HOH 55  455 20   HOH HOH B . 
T 3 HOH 56  456 507  HOH HOH B . 
T 3 HOH 57  457 279  HOH HOH B . 
T 3 HOH 58  458 492  HOH HOH B . 
T 3 HOH 59  459 167  HOH HOH B . 
T 3 HOH 60  460 141  HOH HOH B . 
T 3 HOH 61  461 600  HOH HOH B . 
T 3 HOH 62  462 206  HOH HOH B . 
T 3 HOH 63  463 210  HOH HOH B . 
T 3 HOH 64  464 535  HOH HOH B . 
T 3 HOH 65  465 805  HOH HOH B . 
T 3 HOH 66  466 466  HOH HOH B . 
T 3 HOH 67  467 163  HOH HOH B . 
T 3 HOH 68  468 994  HOH HOH B . 
T 3 HOH 69  469 199  HOH HOH B . 
T 3 HOH 70  470 68   HOH HOH B . 
T 3 HOH 71  471 21   HOH HOH B . 
T 3 HOH 72  472 73   HOH HOH B . 
T 3 HOH 73  473 618  HOH HOH B . 
T 3 HOH 74  474 87   HOH HOH B . 
T 3 HOH 75  475 333  HOH HOH B . 
T 3 HOH 76  476 288  HOH HOH B . 
T 3 HOH 77  477 51   HOH HOH B . 
T 3 HOH 78  478 450  HOH HOH B . 
T 3 HOH 79  479 489  HOH HOH B . 
T 3 HOH 80  480 536  HOH HOH B . 
T 3 HOH 81  481 113  HOH HOH B . 
T 3 HOH 82  482 245  HOH HOH B . 
T 3 HOH 83  483 165  HOH HOH B . 
T 3 HOH 84  484 800  HOH HOH B . 
T 3 HOH 85  485 321  HOH HOH B . 
T 3 HOH 86  486 1019 HOH HOH B . 
T 3 HOH 87  487 263  HOH HOH B . 
T 3 HOH 88  488 301  HOH HOH B . 
T 3 HOH 89  489 574  HOH HOH B . 
T 3 HOH 90  490 587  HOH HOH B . 
T 3 HOH 91  491 277  HOH HOH B . 
T 3 HOH 92  492 482  HOH HOH B . 
T 3 HOH 93  493 691  HOH HOH B . 
T 3 HOH 94  494 989  HOH HOH B . 
T 3 HOH 95  495 755  HOH HOH B . 
T 3 HOH 96  496 588  HOH HOH B . 
T 3 HOH 97  497 858  HOH HOH B . 
T 3 HOH 98  498 283  HOH HOH B . 
T 3 HOH 99  499 9    HOH HOH B . 
T 3 HOH 100 500 702  HOH HOH B . 
T 3 HOH 101 501 143  HOH HOH B . 
T 3 HOH 102 502 344  HOH HOH B . 
T 3 HOH 103 503 293  HOH HOH B . 
T 3 HOH 104 504 955  HOH HOH B . 
T 3 HOH 105 505 453  HOH HOH B . 
T 3 HOH 106 506 359  HOH HOH B . 
T 3 HOH 107 507 256  HOH HOH B . 
T 3 HOH 108 508 727  HOH HOH B . 
T 3 HOH 109 509 227  HOH HOH B . 
T 3 HOH 110 510 465  HOH HOH B . 
T 3 HOH 111 511 360  HOH HOH B . 
T 3 HOH 112 512 984  HOH HOH B . 
T 3 HOH 113 513 638  HOH HOH B . 
T 3 HOH 114 514 687  HOH HOH B . 
T 3 HOH 115 515 1015 HOH HOH B . 
T 3 HOH 116 516 483  HOH HOH B . 
T 3 HOH 117 517 132  HOH HOH B . 
T 3 HOH 118 518 711  HOH HOH B . 
T 3 HOH 119 519 607  HOH HOH B . 
T 3 HOH 120 520 790  HOH HOH B . 
T 3 HOH 121 521 908  HOH HOH B . 
T 3 HOH 122 522 948  HOH HOH B . 
T 3 HOH 123 523 698  HOH HOH B . 
T 3 HOH 124 524 980  HOH HOH B . 
T 3 HOH 125 525 749  HOH HOH B . 
T 3 HOH 126 526 814  HOH HOH B . 
T 3 HOH 127 527 970  HOH HOH B . 
T 3 HOH 128 528 895  HOH HOH B . 
T 3 HOH 129 529 979  HOH HOH B . 
T 3 HOH 130 530 872  HOH HOH B . 
T 3 HOH 131 531 381  HOH HOH B . 
T 3 HOH 132 532 881  HOH HOH B . 
T 3 HOH 133 533 959  HOH HOH B . 
T 3 HOH 134 534 1021 HOH HOH B . 
T 3 HOH 135 535 236  HOH HOH B . 
T 3 HOH 136 536 259  HOH HOH B . 
T 3 HOH 137 537 794  HOH HOH B . 
T 3 HOH 138 538 941  HOH HOH B . 
T 3 HOH 139 539 675  HOH HOH B . 
T 3 HOH 140 540 512  HOH HOH B . 
T 3 HOH 141 541 958  HOH HOH B . 
T 3 HOH 142 542 358  HOH HOH B . 
T 3 HOH 143 543 545  HOH HOH B . 
T 3 HOH 144 544 920  HOH HOH B . 
T 3 HOH 145 545 738  HOH HOH B . 
T 3 HOH 146 546 364  HOH HOH B . 
T 3 HOH 147 547 706  HOH HOH B . 
T 3 HOH 148 548 119  HOH HOH B . 
T 3 HOH 149 549 322  HOH HOH B . 
T 3 HOH 150 550 369  HOH HOH B . 
T 3 HOH 151 551 699  HOH HOH B . 
T 3 HOH 152 552 680  HOH HOH B . 
T 3 HOH 153 553 997  HOH HOH B . 
T 3 HOH 154 554 968  HOH HOH B . 
T 3 HOH 155 555 902  HOH HOH B . 
T 3 HOH 156 556 357  HOH HOH B . 
T 3 HOH 157 557 1000 HOH HOH B . 
T 3 HOH 158 558 1018 HOH HOH B . 
T 3 HOH 159 559 831  HOH HOH B . 
T 3 HOH 160 560 763  HOH HOH B . 
T 3 HOH 161 561 857  HOH HOH B . 
T 3 HOH 162 562 258  HOH HOH B . 
T 3 HOH 163 563 779  HOH HOH B . 
T 3 HOH 164 564 1013 HOH HOH B . 
T 3 HOH 165 565 993  HOH HOH B . 
T 3 HOH 166 566 977  HOH HOH B . 
T 3 HOH 167 567 907  HOH HOH B . 
T 3 HOH 168 568 766  HOH HOH B . 
T 3 HOH 169 569 1032 HOH HOH B . 
T 3 HOH 170 570 497  HOH HOH B . 
T 3 HOH 171 571 976  HOH HOH B . 
T 3 HOH 172 572 341  HOH HOH B . 
T 3 HOH 173 573 904  HOH HOH B . 
T 3 HOH 174 574 184  HOH HOH B . 
T 3 HOH 175 575 962  HOH HOH B . 
T 3 HOH 176 576 1047 HOH HOH B . 
T 3 HOH 177 577 848  HOH HOH B . 
T 3 HOH 178 578 668  HOH HOH B . 
T 3 HOH 179 579 882  HOH HOH B . 
T 3 HOH 180 580 975  HOH HOH B . 
T 3 HOH 181 581 924  HOH HOH B . 
T 3 HOH 182 582 1049 HOH HOH B . 
U 3 HOH 1   401 226  HOH HOH C . 
U 3 HOH 2   402 935  HOH HOH C . 
U 3 HOH 3   403 479  HOH HOH C . 
U 3 HOH 4   404 720  HOH HOH C . 
U 3 HOH 5   405 473  HOH HOH C . 
U 3 HOH 6   406 97   HOH HOH C . 
U 3 HOH 7   407 599  HOH HOH C . 
U 3 HOH 8   408 36   HOH HOH C . 
U 3 HOH 9   409 659  HOH HOH C . 
U 3 HOH 10  410 34   HOH HOH C . 
U 3 HOH 11  411 18   HOH HOH C . 
U 3 HOH 12  412 176  HOH HOH C . 
U 3 HOH 13  413 876  HOH HOH C . 
U 3 HOH 14  414 33   HOH HOH C . 
U 3 HOH 15  415 405  HOH HOH C . 
U 3 HOH 16  416 395  HOH HOH C . 
U 3 HOH 17  417 388  HOH HOH C . 
U 3 HOH 18  418 500  HOH HOH C . 
U 3 HOH 19  419 442  HOH HOH C . 
U 3 HOH 20  420 411  HOH HOH C . 
U 3 HOH 21  421 191  HOH HOH C . 
U 3 HOH 22  422 353  HOH HOH C . 
U 3 HOH 23  423 29   HOH HOH C . 
U 3 HOH 24  424 484  HOH HOH C . 
U 3 HOH 25  425 148  HOH HOH C . 
U 3 HOH 26  426 153  HOH HOH C . 
U 3 HOH 27  427 241  HOH HOH C . 
U 3 HOH 28  428 85   HOH HOH C . 
U 3 HOH 29  429 502  HOH HOH C . 
U 3 HOH 30  430 25   HOH HOH C . 
U 3 HOH 31  431 164  HOH HOH C . 
U 3 HOH 32  432 579  HOH HOH C . 
U 3 HOH 33  433 112  HOH HOH C . 
U 3 HOH 34  434 468  HOH HOH C . 
U 3 HOH 35  435 331  HOH HOH C . 
U 3 HOH 36  436 93   HOH HOH C . 
U 3 HOH 37  437 776  HOH HOH C . 
U 3 HOH 38  438 568  HOH HOH C . 
U 3 HOH 39  439 570  HOH HOH C . 
U 3 HOH 40  440 370  HOH HOH C . 
U 3 HOH 41  441 219  HOH HOH C . 
U 3 HOH 42  442 426  HOH HOH C . 
U 3 HOH 43  443 70   HOH HOH C . 
U 3 HOH 44  444 95   HOH HOH C . 
U 3 HOH 45  445 126  HOH HOH C . 
U 3 HOH 46  446 229  HOH HOH C . 
U 3 HOH 47  447 30   HOH HOH C . 
U 3 HOH 48  448 13   HOH HOH C . 
U 3 HOH 49  449 505  HOH HOH C . 
U 3 HOH 50  450 447  HOH HOH C . 
U 3 HOH 51  451 692  HOH HOH C . 
U 3 HOH 52  452 107  HOH HOH C . 
U 3 HOH 53  453 683  HOH HOH C . 
U 3 HOH 54  454 213  HOH HOH C . 
U 3 HOH 55  455 220  HOH HOH C . 
U 3 HOH 56  456 152  HOH HOH C . 
U 3 HOH 57  457 287  HOH HOH C . 
U 3 HOH 58  458 685  HOH HOH C . 
U 3 HOH 59  459 193  HOH HOH C . 
U 3 HOH 60  460 133  HOH HOH C . 
U 3 HOH 61  461 66   HOH HOH C . 
U 3 HOH 62  462 1054 HOH HOH C . 
U 3 HOH 63  463 643  HOH HOH C . 
U 3 HOH 64  464 628  HOH HOH C . 
U 3 HOH 65  465 596  HOH HOH C . 
U 3 HOH 66  466 952  HOH HOH C . 
U 3 HOH 67  467 242  HOH HOH C . 
U 3 HOH 68  468 275  HOH HOH C . 
U 3 HOH 69  469 327  HOH HOH C . 
U 3 HOH 70  470 71   HOH HOH C . 
U 3 HOH 71  471 83   HOH HOH C . 
U 3 HOH 72  472 237  HOH HOH C . 
U 3 HOH 73  473 722  HOH HOH C . 
U 3 HOH 74  474 325  HOH HOH C . 
U 3 HOH 75  475 356  HOH HOH C . 
U 3 HOH 76  476 633  HOH HOH C . 
U 3 HOH 77  477 686  HOH HOH C . 
U 3 HOH 78  478 315  HOH HOH C . 
U 3 HOH 79  479 646  HOH HOH C . 
U 3 HOH 80  480 564  HOH HOH C . 
U 3 HOH 81  481 209  HOH HOH C . 
U 3 HOH 82  482 752  HOH HOH C . 
U 3 HOH 83  483 534  HOH HOH C . 
U 3 HOH 84  484 200  HOH HOH C . 
U 3 HOH 85  485 2    HOH HOH C . 
U 3 HOH 86  486 90   HOH HOH C . 
U 3 HOH 87  487 305  HOH HOH C . 
U 3 HOH 88  488 737  HOH HOH C . 
U 3 HOH 89  489 158  HOH HOH C . 
U 3 HOH 90  490 385  HOH HOH C . 
U 3 HOH 91  491 272  HOH HOH C . 
U 3 HOH 92  492 513  HOH HOH C . 
U 3 HOH 93  493 604  HOH HOH C . 
U 3 HOH 94  494 170  HOH HOH C . 
U 3 HOH 95  495 363  HOH HOH C . 
U 3 HOH 96  496 845  HOH HOH C . 
U 3 HOH 97  497 708  HOH HOH C . 
U 3 HOH 98  498 457  HOH HOH C . 
U 3 HOH 99  499 431  HOH HOH C . 
U 3 HOH 100 500 859  HOH HOH C . 
U 3 HOH 101 501 409  HOH HOH C . 
U 3 HOH 102 502 118  HOH HOH C . 
U 3 HOH 103 503 662  HOH HOH C . 
U 3 HOH 104 504 171  HOH HOH C . 
U 3 HOH 105 505 781  HOH HOH C . 
U 3 HOH 106 506 1041 HOH HOH C . 
U 3 HOH 107 507 397  HOH HOH C . 
U 3 HOH 108 508 923  HOH HOH C . 
U 3 HOH 109 509 481  HOH HOH C . 
U 3 HOH 110 510 864  HOH HOH C . 
U 3 HOH 111 511 271  HOH HOH C . 
U 3 HOH 112 512 537  HOH HOH C . 
U 3 HOH 113 513 17   HOH HOH C . 
U 3 HOH 114 514 460  HOH HOH C . 
U 3 HOH 115 515 563  HOH HOH C . 
U 3 HOH 116 516 940  HOH HOH C . 
U 3 HOH 117 517 362  HOH HOH C . 
U 3 HOH 118 518 1001 HOH HOH C . 
U 3 HOH 119 519 929  HOH HOH C . 
U 3 HOH 120 520 445  HOH HOH C . 
U 3 HOH 121 521 248  HOH HOH C . 
U 3 HOH 122 522 269  HOH HOH C . 
U 3 HOH 123 523 338  HOH HOH C . 
U 3 HOH 124 524 862  HOH HOH C . 
U 3 HOH 125 525 231  HOH HOH C . 
U 3 HOH 126 526 950  HOH HOH C . 
U 3 HOH 127 527 621  HOH HOH C . 
U 3 HOH 128 528 581  HOH HOH C . 
U 3 HOH 129 529 1029 HOH HOH C . 
U 3 HOH 130 530 919  HOH HOH C . 
U 3 HOH 131 531 981  HOH HOH C . 
U 3 HOH 132 532 741  HOH HOH C . 
U 3 HOH 133 533 340  HOH HOH C . 
U 3 HOH 134 534 1016 HOH HOH C . 
U 3 HOH 135 535 533  HOH HOH C . 
U 3 HOH 136 536 965  HOH HOH C . 
U 3 HOH 137 537 306  HOH HOH C . 
U 3 HOH 138 538 1007 HOH HOH C . 
U 3 HOH 139 539 238  HOH HOH C . 
U 3 HOH 140 540 765  HOH HOH C . 
U 3 HOH 141 541 547  HOH HOH C . 
U 3 HOH 142 542 681  HOH HOH C . 
U 3 HOH 143 543 1067 HOH HOH C . 
U 3 HOH 144 544 1036 HOH HOH C . 
U 3 HOH 145 545 531  HOH HOH C . 
U 3 HOH 146 546 886  HOH HOH C . 
U 3 HOH 147 547 542  HOH HOH C . 
U 3 HOH 148 548 995  HOH HOH C . 
U 3 HOH 149 549 609  HOH HOH C . 
U 3 HOH 150 550 712  HOH HOH C . 
U 3 HOH 151 551 822  HOH HOH C . 
U 3 HOH 152 552 577  HOH HOH C . 
U 3 HOH 153 553 569  HOH HOH C . 
U 3 HOH 154 554 472  HOH HOH C . 
U 3 HOH 155 555 700  HOH HOH C . 
U 3 HOH 156 556 823  HOH HOH C . 
U 3 HOH 157 557 637  HOH HOH C . 
U 3 HOH 158 558 855  HOH HOH C . 
U 3 HOH 159 559 1028 HOH HOH C . 
U 3 HOH 160 560 253  HOH HOH C . 
U 3 HOH 161 561 162  HOH HOH C . 
U 3 HOH 162 562 469  HOH HOH C . 
U 3 HOH 163 563 499  HOH HOH C . 
U 3 HOH 164 564 156  HOH HOH C . 
U 3 HOH 165 565 671  HOH HOH C . 
U 3 HOH 166 566 778  HOH HOH C . 
U 3 HOH 167 567 624  HOH HOH C . 
U 3 HOH 168 568 828  HOH HOH C . 
U 3 HOH 169 569 988  HOH HOH C . 
U 3 HOH 170 570 371  HOH HOH C . 
U 3 HOH 171 571 1066 HOH HOH C . 
U 3 HOH 172 572 918  HOH HOH C . 
U 3 HOH 173 573 626  HOH HOH C . 
U 3 HOH 174 574 538  HOH HOH C . 
U 3 HOH 175 575 1030 HOH HOH C . 
U 3 HOH 176 576 1064 HOH HOH C . 
U 3 HOH 177 577 983  HOH HOH C . 
U 3 HOH 178 578 745  HOH HOH C . 
U 3 HOH 179 579 1020 HOH HOH C . 
V 3 HOH 1   401 1022 HOH HOH D . 
V 3 HOH 2   402 268  HOH HOH D . 
V 3 HOH 3   403 804  HOH HOH D . 
V 3 HOH 4   404 608  HOH HOH D . 
V 3 HOH 5   405 494  HOH HOH D . 
V 3 HOH 6   406 196  HOH HOH D . 
V 3 HOH 7   407 429  HOH HOH D . 
V 3 HOH 8   408 297  HOH HOH D . 
V 3 HOH 9   409 52   HOH HOH D . 
V 3 HOH 10  410 1034 HOH HOH D . 
V 3 HOH 11  411 709  HOH HOH D . 
V 3 HOH 12  412 124  HOH HOH D . 
V 3 HOH 13  413 452  HOH HOH D . 
V 3 HOH 14  414 161  HOH HOH D . 
V 3 HOH 15  415 255  HOH HOH D . 
V 3 HOH 16  416 35   HOH HOH D . 
V 3 HOH 17  417 135  HOH HOH D . 
V 3 HOH 18  418 414  HOH HOH D . 
V 3 HOH 19  419 44   HOH HOH D . 
V 3 HOH 20  420 116  HOH HOH D . 
V 3 HOH 21  421 780  HOH HOH D . 
V 3 HOH 22  422 679  HOH HOH D . 
V 3 HOH 23  423 407  HOH HOH D . 
V 3 HOH 24  424 106  HOH HOH D . 
V 3 HOH 25  425 592  HOH HOH D . 
V 3 HOH 26  426 310  HOH HOH D . 
V 3 HOH 27  427 509  HOH HOH D . 
V 3 HOH 28  428 665  HOH HOH D . 
V 3 HOH 29  429 218  HOH HOH D . 
V 3 HOH 30  430 793  HOH HOH D . 
V 3 HOH 31  431 84   HOH HOH D . 
V 3 HOH 32  432 458  HOH HOH D . 
V 3 HOH 33  433 181  HOH HOH D . 
V 3 HOH 34  434 129  HOH HOH D . 
V 3 HOH 35  435 825  HOH HOH D . 
V 3 HOH 36  436 394  HOH HOH D . 
V 3 HOH 37  437 270  HOH HOH D . 
V 3 HOH 38  438 764  HOH HOH D . 
V 3 HOH 39  439 597  HOH HOH D . 
V 3 HOH 40  440 645  HOH HOH D . 
V 3 HOH 41  441 91   HOH HOH D . 
V 3 HOH 42  442 235  HOH HOH D . 
V 3 HOH 43  443 549  HOH HOH D . 
V 3 HOH 44  444 550  HOH HOH D . 
V 3 HOH 45  445 566  HOH HOH D . 
V 3 HOH 46  446 127  HOH HOH D . 
V 3 HOH 47  447 198  HOH HOH D . 
V 3 HOH 48  448 111  HOH HOH D . 
V 3 HOH 49  449 4    HOH HOH D . 
V 3 HOH 50  450 834  HOH HOH D . 
V 3 HOH 51  451 806  HOH HOH D . 
V 3 HOH 52  452 96   HOH HOH D . 
V 3 HOH 53  453 503  HOH HOH D . 
V 3 HOH 54  454 754  HOH HOH D . 
V 3 HOH 55  455 43   HOH HOH D . 
V 3 HOH 56  456 580  HOH HOH D . 
V 3 HOH 57  457 296  HOH HOH D . 
V 3 HOH 58  458 791  HOH HOH D . 
V 3 HOH 59  459 402  HOH HOH D . 
V 3 HOH 60  460 224  HOH HOH D . 
V 3 HOH 61  461 142  HOH HOH D . 
V 3 HOH 62  462 217  HOH HOH D . 
V 3 HOH 63  463 60   HOH HOH D . 
V 3 HOH 64  464 777  HOH HOH D . 
V 3 HOH 65  465 585  HOH HOH D . 
V 3 HOH 66  466 761  HOH HOH D . 
V 3 HOH 67  467 425  HOH HOH D . 
V 3 HOH 68  468 110  HOH HOH D . 
V 3 HOH 69  469 16   HOH HOH D . 
V 3 HOH 70  470 562  HOH HOH D . 
V 3 HOH 71  471 462  HOH HOH D . 
V 3 HOH 72  472 578  HOH HOH D . 
V 3 HOH 73  473 375  HOH HOH D . 
V 3 HOH 74  474 159  HOH HOH D . 
V 3 HOH 75  475 400  HOH HOH D . 
V 3 HOH 76  476 801  HOH HOH D . 
V 3 HOH 77  477 838  HOH HOH D . 
V 3 HOH 78  478 890  HOH HOH D . 
V 3 HOH 79  479 380  HOH HOH D . 
V 3 HOH 80  480 278  HOH HOH D . 
V 3 HOH 81  481 498  HOH HOH D . 
V 3 HOH 82  482 144  HOH HOH D . 
V 3 HOH 83  483 178  HOH HOH D . 
V 3 HOH 84  484 832  HOH HOH D . 
V 3 HOH 85  485 559  HOH HOH D . 
V 3 HOH 86  486 399  HOH HOH D . 
V 3 HOH 87  487 120  HOH HOH D . 
V 3 HOH 88  488 664  HOH HOH D . 
V 3 HOH 89  489 53   HOH HOH D . 
V 3 HOH 90  490 1065 HOH HOH D . 
V 3 HOH 91  491 1035 HOH HOH D . 
V 3 HOH 92  492 898  HOH HOH D . 
V 3 HOH 93  493 961  HOH HOH D . 
V 3 HOH 94  494 854  HOH HOH D . 
V 3 HOH 95  495 796  HOH HOH D . 
V 3 HOH 96  496 841  HOH HOH D . 
V 3 HOH 97  497 658  HOH HOH D . 
V 3 HOH 98  498 655  HOH HOH D . 
V 3 HOH 99  499 710  HOH HOH D . 
V 3 HOH 100 500 678  HOH HOH D . 
V 3 HOH 101 501 844  HOH HOH D . 
V 3 HOH 102 502 840  HOH HOH D . 
V 3 HOH 103 503 316  HOH HOH D . 
V 3 HOH 104 504 769  HOH HOH D . 
V 3 HOH 105 505 629  HOH HOH D . 
V 3 HOH 106 506 807  HOH HOH D . 
V 3 HOH 107 507 623  HOH HOH D . 
V 3 HOH 108 508 543  HOH HOH D . 
V 3 HOH 109 509 1046 HOH HOH D . 
V 3 HOH 110 510 309  HOH HOH D . 
V 3 HOH 111 511 874  HOH HOH D . 
V 3 HOH 112 512 1057 HOH HOH D . 
V 3 HOH 113 513 901  HOH HOH D . 
V 3 HOH 114 514 619  HOH HOH D . 
V 3 HOH 115 515 782  HOH HOH D . 
V 3 HOH 116 516 873  HOH HOH D . 
V 3 HOH 117 517 261  HOH HOH D . 
V 3 HOH 118 518 606  HOH HOH D . 
V 3 HOH 119 519 768  HOH HOH D . 
V 3 HOH 120 520 861  HOH HOH D . 
V 3 HOH 121 521 893  HOH HOH D . 
V 3 HOH 122 522 740  HOH HOH D . 
V 3 HOH 123 523 987  HOH HOH D . 
V 3 HOH 124 524 775  HOH HOH D . 
V 3 HOH 125 525 877  HOH HOH D . 
V 3 HOH 126 526 978  HOH HOH D . 
V 3 HOH 127 527 281  HOH HOH D . 
V 3 HOH 128 528 367  HOH HOH D . 
V 3 HOH 129 529 1059 HOH HOH D . 
V 3 HOH 130 530 812  HOH HOH D . 
V 3 HOH 131 531 865  HOH HOH D . 
V 3 HOH 132 532 985  HOH HOH D . 
V 3 HOH 133 533 641  HOH HOH D . 
V 3 HOH 134 534 1068 HOH HOH D . 
V 3 HOH 135 535 1009 HOH HOH D . 
V 3 HOH 136 536 773  HOH HOH D . 
V 3 HOH 137 537 990  HOH HOH D . 
V 3 HOH 138 538 991  HOH HOH D . 
V 3 HOH 139 539 308  HOH HOH D . 
V 3 HOH 140 540 1056 HOH HOH D . 
V 3 HOH 141 541 971  HOH HOH D . 
V 3 HOH 142 542 602  HOH HOH D . 
V 3 HOH 143 543 784  HOH HOH D . 
V 3 HOH 144 544 265  HOH HOH D . 
V 3 HOH 145 545 767  HOH HOH D . 
V 3 HOH 146 546 809  HOH HOH D . 
W 3 HOH 1   401 491  HOH HOH E . 
W 3 HOH 2   402 480  HOH HOH E . 
W 3 HOH 3   403 303  HOH HOH E . 
W 3 HOH 4   404 707  HOH HOH E . 
W 3 HOH 5   405 870  HOH HOH E . 
W 3 HOH 6   406 212  HOH HOH E . 
W 3 HOH 7   407 728  HOH HOH E . 
W 3 HOH 8   408 56   HOH HOH E . 
W 3 HOH 9   409 103  HOH HOH E . 
W 3 HOH 10  410 427  HOH HOH E . 
W 3 HOH 11  411 15   HOH HOH E . 
W 3 HOH 12  412 355  HOH HOH E . 
W 3 HOH 13  413 435  HOH HOH E . 
W 3 HOH 14  414 860  HOH HOH E . 
W 3 HOH 15  415 28   HOH HOH E . 
W 3 HOH 16  416 894  HOH HOH E . 
W 3 HOH 17  417 546  HOH HOH E . 
W 3 HOH 18  418 250  HOH HOH E . 
W 3 HOH 19  419 78   HOH HOH E . 
W 3 HOH 20  420 663  HOH HOH E . 
W 3 HOH 21  421 37   HOH HOH E . 
W 3 HOH 22  422 108  HOH HOH E . 
W 3 HOH 23  423 887  HOH HOH E . 
W 3 HOH 24  424 46   HOH HOH E . 
W 3 HOH 25  425 215  HOH HOH E . 
W 3 HOH 26  426 324  HOH HOH E . 
W 3 HOH 27  427 179  HOH HOH E . 
W 3 HOH 28  428 813  HOH HOH E . 
W 3 HOH 29  429 417  HOH HOH E . 
W 3 HOH 30  430 347  HOH HOH E . 
W 3 HOH 31  431 403  HOH HOH E . 
W 3 HOH 32  432 260  HOH HOH E . 
W 3 HOH 33  433 565  HOH HOH E . 
W 3 HOH 34  434 408  HOH HOH E . 
W 3 HOH 35  435 1050 HOH HOH E . 
W 3 HOH 36  436 150  HOH HOH E . 
W 3 HOH 37  437 439  HOH HOH E . 
W 3 HOH 38  438 573  HOH HOH E . 
W 3 HOH 39  439 656  HOH HOH E . 
W 3 HOH 40  440 89   HOH HOH E . 
W 3 HOH 41  441 239  HOH HOH E . 
W 3 HOH 42  442 454  HOH HOH E . 
W 3 HOH 43  443 77   HOH HOH E . 
W 3 HOH 44  444 139  HOH HOH E . 
W 3 HOH 45  445 125  HOH HOH E . 
W 3 HOH 46  446 314  HOH HOH E . 
W 3 HOH 47  447 392  HOH HOH E . 
W 3 HOH 48  448 312  HOH HOH E . 
W 3 HOH 49  449 140  HOH HOH E . 
W 3 HOH 50  450 953  HOH HOH E . 
W 3 HOH 51  451 41   HOH HOH E . 
W 3 HOH 52  452 27   HOH HOH E . 
W 3 HOH 53  453 233  HOH HOH E . 
W 3 HOH 54  454 1060 HOH HOH E . 
W 3 HOH 55  455 298  HOH HOH E . 
W 3 HOH 56  456 276  HOH HOH E . 
W 3 HOH 57  457 32   HOH HOH E . 
W 3 HOH 58  458 197  HOH HOH E . 
W 3 HOH 59  459 810  HOH HOH E . 
W 3 HOH 60  460 931  HOH HOH E . 
W 3 HOH 61  461 553  HOH HOH E . 
W 3 HOH 62  462 190  HOH HOH E . 
W 3 HOH 63  463 99   HOH HOH E . 
W 3 HOH 64  464 520  HOH HOH E . 
W 3 HOH 65  465 391  HOH HOH E . 
W 3 HOH 66  466 232  HOH HOH E . 
W 3 HOH 67  467 393  HOH HOH E . 
W 3 HOH 68  468 446  HOH HOH E . 
W 3 HOH 69  469 667  HOH HOH E . 
W 3 HOH 70  470 319  HOH HOH E . 
W 3 HOH 71  471 797  HOH HOH E . 
W 3 HOH 72  472 138  HOH HOH E . 
W 3 HOH 73  473 372  HOH HOH E . 
W 3 HOH 74  474 718  HOH HOH E . 
W 3 HOH 75  475 307  HOH HOH E . 
W 3 HOH 76  476 696  HOH HOH E . 
W 3 HOH 77  477 666  HOH HOH E . 
W 3 HOH 78  478 677  HOH HOH E . 
W 3 HOH 79  479 185  HOH HOH E . 
W 3 HOH 80  480 216  HOH HOH E . 
W 3 HOH 81  481 798  HOH HOH E . 
W 3 HOH 82  482 501  HOH HOH E . 
W 3 HOH 83  483 632  HOH HOH E . 
W 3 HOH 84  484 49   HOH HOH E . 
W 3 HOH 85  485 294  HOH HOH E . 
W 3 HOH 86  486 644  HOH HOH E . 
W 3 HOH 87  487 1038 HOH HOH E . 
W 3 HOH 88  488 3    HOH HOH E . 
W 3 HOH 89  489 257  HOH HOH E . 
W 3 HOH 90  490 471  HOH HOH E . 
W 3 HOH 91  491 661  HOH HOH E . 
W 3 HOH 92  492 478  HOH HOH E . 
W 3 HOH 93  493 8    HOH HOH E . 
W 3 HOH 94  494 556  HOH HOH E . 
W 3 HOH 95  495 58   HOH HOH E . 
W 3 HOH 96  496 221  HOH HOH E . 
W 3 HOH 97  497 121  HOH HOH E . 
W 3 HOH 98  498 230  HOH HOH E . 
W 3 HOH 99  499 175  HOH HOH E . 
W 3 HOH 100 500 605  HOH HOH E . 
W 3 HOH 101 501 508  HOH HOH E . 
W 3 HOH 102 502 337  HOH HOH E . 
W 3 HOH 103 503 378  HOH HOH E . 
W 3 HOH 104 504 383  HOH HOH E . 
W 3 HOH 105 505 521  HOH HOH E . 
W 3 HOH 106 506 266  HOH HOH E . 
W 3 HOH 107 507 704  HOH HOH E . 
W 3 HOH 108 508 1010 HOH HOH E . 
W 3 HOH 109 509 695  HOH HOH E . 
W 3 HOH 110 510 517  HOH HOH E . 
W 3 HOH 111 511 946  HOH HOH E . 
W 3 HOH 112 512 336  HOH HOH E . 
W 3 HOH 113 513 642  HOH HOH E . 
W 3 HOH 114 514 352  HOH HOH E . 
W 3 HOH 115 515 584  HOH HOH E . 
W 3 HOH 116 516 514  HOH HOH E . 
W 3 HOH 117 517 300  HOH HOH E . 
W 3 HOH 118 518 843  HOH HOH E . 
W 3 HOH 119 519 436  HOH HOH E . 
W 3 HOH 120 520 451  HOH HOH E . 
W 3 HOH 121 521 792  HOH HOH E . 
W 3 HOH 122 522 974  HOH HOH E . 
W 3 HOH 123 523 1037 HOH HOH E . 
W 3 HOH 124 524 172  HOH HOH E . 
W 3 HOH 125 525 863  HOH HOH E . 
W 3 HOH 126 526 485  HOH HOH E . 
W 3 HOH 127 527 713  HOH HOH E . 
W 3 HOH 128 528 729  HOH HOH E . 
W 3 HOH 129 529 539  HOH HOH E . 
W 3 HOH 130 530 613  HOH HOH E . 
W 3 HOH 131 531 647  HOH HOH E . 
W 3 HOH 132 532 434  HOH HOH E . 
W 3 HOH 133 533 47   HOH HOH E . 
W 3 HOH 134 534 884  HOH HOH E . 
W 3 HOH 135 535 789  HOH HOH E . 
W 3 HOH 136 536 329  HOH HOH E . 
W 3 HOH 137 537 201  HOH HOH E . 
W 3 HOH 138 538 572  HOH HOH E . 
W 3 HOH 139 539 973  HOH HOH E . 
W 3 HOH 140 540 527  HOH HOH E . 
W 3 HOH 141 541 986  HOH HOH E . 
W 3 HOH 142 542 930  HOH HOH E . 
W 3 HOH 143 543 374  HOH HOH E . 
W 3 HOH 144 544 149  HOH HOH E . 
W 3 HOH 145 545 736  HOH HOH E . 
W 3 HOH 146 546 811  HOH HOH E . 
W 3 HOH 147 547 495  HOH HOH E . 
W 3 HOH 148 548 195  HOH HOH E . 
W 3 HOH 149 549 75   HOH HOH E . 
W 3 HOH 150 550 760  HOH HOH E . 
W 3 HOH 151 551 996  HOH HOH E . 
W 3 HOH 152 552 635  HOH HOH E . 
W 3 HOH 153 553 437  HOH HOH E . 
W 3 HOH 154 554 837  HOH HOH E . 
W 3 HOH 155 555 963  HOH HOH E . 
W 3 HOH 156 556 443  HOH HOH E . 
W 3 HOH 157 557 345  HOH HOH E . 
W 3 HOH 158 558 254  HOH HOH E . 
W 3 HOH 159 559 1042 HOH HOH E . 
W 3 HOH 160 560 934  HOH HOH E . 
W 3 HOH 161 561 847  HOH HOH E . 
W 3 HOH 162 562 839  HOH HOH E . 
W 3 HOH 163 563 759  HOH HOH E . 
W 3 HOH 164 564 917  HOH HOH E . 
W 3 HOH 165 565 701  HOH HOH E . 
W 3 HOH 166 566 945  HOH HOH E . 
W 3 HOH 167 567 785  HOH HOH E . 
W 3 HOH 168 568 746  HOH HOH E . 
W 3 HOH 169 569 815  HOH HOH E . 
W 3 HOH 170 570 891  HOH HOH E . 
W 3 HOH 171 571 284  HOH HOH E . 
X 3 HOH 1   401 470  HOH HOH F . 
X 3 HOH 2   402 693  HOH HOH F . 
X 3 HOH 3   403 438  HOH HOH F . 
X 3 HOH 4   404 214  HOH HOH F . 
X 3 HOH 5   405 173  HOH HOH F . 
X 3 HOH 6   406 10   HOH HOH F . 
X 3 HOH 7   407 504  HOH HOH F . 
X 3 HOH 8   408 100  HOH HOH F . 
X 3 HOH 9   409 616  HOH HOH F . 
X 3 HOH 10  410 1025 HOH HOH F . 
X 3 HOH 11  411 157  HOH HOH F . 
X 3 HOH 12  412 205  HOH HOH F . 
X 3 HOH 13  413 770  HOH HOH F . 
X 3 HOH 14  414 772  HOH HOH F . 
X 3 HOH 15  415 379  HOH HOH F . 
X 3 HOH 16  416 343  HOH HOH F . 
X 3 HOH 17  417 251  HOH HOH F . 
X 3 HOH 18  418 114  HOH HOH F . 
X 3 HOH 19  419 627  HOH HOH F . 
X 3 HOH 20  420 1023 HOH HOH F . 
X 3 HOH 21  421 222  HOH HOH F . 
X 3 HOH 22  422 424  HOH HOH F . 
X 3 HOH 23  423 48   HOH HOH F . 
X 3 HOH 24  424 330  HOH HOH F . 
X 3 HOH 25  425 55   HOH HOH F . 
X 3 HOH 26  426 40   HOH HOH F . 
X 3 HOH 27  427 802  HOH HOH F . 
X 3 HOH 28  428 102  HOH HOH F . 
X 3 HOH 29  429 640  HOH HOH F . 
X 3 HOH 30  430 349  HOH HOH F . 
X 3 HOH 31  431 11   HOH HOH F . 
X 3 HOH 32  432 247  HOH HOH F . 
X 3 HOH 33  433 295  HOH HOH F . 
X 3 HOH 34  434 541  HOH HOH F . 
X 3 HOH 35  435 657  HOH HOH F . 
X 3 HOH 36  436 323  HOH HOH F . 
X 3 HOH 37  437 441  HOH HOH F . 
X 3 HOH 38  438 22   HOH HOH F . 
X 3 HOH 39  439 786  HOH HOH F . 
X 3 HOH 40  440 688  HOH HOH F . 
X 3 HOH 41  441 187  HOH HOH F . 
X 3 HOH 42  442 240  HOH HOH F . 
X 3 HOH 43  443 386  HOH HOH F . 
X 3 HOH 44  444 824  HOH HOH F . 
X 3 HOH 45  445 816  HOH HOH F . 
X 3 HOH 46  446 45   HOH HOH F . 
X 3 HOH 47  447 614  HOH HOH F . 
X 3 HOH 48  448 552  HOH HOH F . 
X 3 HOH 49  449 610  HOH HOH F . 
X 3 HOH 50  450 160  HOH HOH F . 
X 3 HOH 51  451 180  HOH HOH F . 
X 3 HOH 52  452 634  HOH HOH F . 
X 3 HOH 53  453 117  HOH HOH F . 
X 3 HOH 54  454 622  HOH HOH F . 
X 3 HOH 55  455 724  HOH HOH F . 
X 3 HOH 56  456 186  HOH HOH F . 
X 3 HOH 57  457 842  HOH HOH F . 
X 3 HOH 58  458 795  HOH HOH F . 
X 3 HOH 59  459 676  HOH HOH F . 
X 3 HOH 60  460 188  HOH HOH F . 
X 3 HOH 61  461 836  HOH HOH F . 
X 3 HOH 62  462 335  HOH HOH F . 
X 3 HOH 63  463 928  HOH HOH F . 
X 3 HOH 64  464 516  HOH HOH F . 
X 3 HOH 65  465 669  HOH HOH F . 
X 3 HOH 66  466 422  HOH HOH F . 
X 3 HOH 67  467 332  HOH HOH F . 
X 3 HOH 68  468 354  HOH HOH F . 
X 3 HOH 69  469 92   HOH HOH F . 
X 3 HOH 70  470 639  HOH HOH F . 
X 3 HOH 71  471 560  HOH HOH F . 
X 3 HOH 72  472 42   HOH HOH F . 
X 3 HOH 73  473 651  HOH HOH F . 
X 3 HOH 74  474 672  HOH HOH F . 
X 3 HOH 75  475 529  HOH HOH F . 
X 3 HOH 76  476 122  HOH HOH F . 
X 3 HOH 77  477 703  HOH HOH F . 
X 3 HOH 78  478 94   HOH HOH F . 
X 3 HOH 79  479 79   HOH HOH F . 
X 3 HOH 80  480 264  HOH HOH F . 
X 3 HOH 81  481 506  HOH HOH F . 
X 3 HOH 82  482 1048 HOH HOH F . 
X 3 HOH 83  483 589  HOH HOH F . 
X 3 HOH 84  484 455  HOH HOH F . 
X 3 HOH 85  485 168  HOH HOH F . 
X 3 HOH 86  486 551  HOH HOH F . 
X 3 HOH 87  487 830  HOH HOH F . 
X 3 HOH 88  488 582  HOH HOH F . 
X 3 HOH 89  489 753  HOH HOH F . 
X 3 HOH 90  490 817  HOH HOH F . 
X 3 HOH 91  491 304  HOH HOH F . 
X 3 HOH 92  492 361  HOH HOH F . 
X 3 HOH 93  493 598  HOH HOH F . 
X 3 HOH 94  494 957  HOH HOH F . 
X 3 HOH 95  495 243  HOH HOH F . 
X 3 HOH 96  496 137  HOH HOH F . 
X 3 HOH 97  497 721  HOH HOH F . 
X 3 HOH 98  498 1033 HOH HOH F . 
X 3 HOH 99  499 783  HOH HOH F . 
X 3 HOH 100 500 849  HOH HOH F . 
X 3 HOH 101 501 249  HOH HOH F . 
X 3 HOH 102 502 558  HOH HOH F . 
X 3 HOH 103 503 690  HOH HOH F . 
X 3 HOH 104 504 660  HOH HOH F . 
X 3 HOH 105 505 476  HOH HOH F . 
X 3 HOH 106 506 1011 HOH HOH F . 
X 3 HOH 107 507 889  HOH HOH F . 
X 3 HOH 108 508 1044 HOH HOH F . 
X 3 HOH 109 509 567  HOH HOH F . 
X 3 HOH 110 510 913  HOH HOH F . 
X 3 HOH 111 511 54   HOH HOH F . 
X 3 HOH 112 512 818  HOH HOH F . 
X 3 HOH 113 513 821  HOH HOH F . 
X 3 HOH 114 514 732  HOH HOH F . 
X 3 HOH 115 515 1045 HOH HOH F . 
X 3 HOH 116 516 612  HOH HOH F . 
X 3 HOH 117 517 742  HOH HOH F . 
X 3 HOH 118 518 947  HOH HOH F . 
X 3 HOH 119 519 851  HOH HOH F . 
X 3 HOH 120 520 463  HOH HOH F . 
X 3 HOH 121 521 1051 HOH HOH F . 
X 3 HOH 122 522 1070 HOH HOH F . 
X 3 HOH 123 523 954  HOH HOH F . 
X 3 HOH 124 524 1058 HOH HOH F . 
X 3 HOH 125 525 967  HOH HOH F . 
X 3 HOH 126 526 1063 HOH HOH F . 
X 3 HOH 127 527 350  HOH HOH F . 
X 3 HOH 128 528 871  HOH HOH F . 
X 3 HOH 129 529 739  HOH HOH F . 
X 3 HOH 130 530 682  HOH HOH F . 
X 3 HOH 131 531 758  HOH HOH F . 
X 3 HOH 132 532 757  HOH HOH F . 
X 3 HOH 133 533 969  HOH HOH F . 
X 3 HOH 134 534 925  HOH HOH F . 
X 3 HOH 135 535 866  HOH HOH F . 
X 3 HOH 136 536 267  HOH HOH F . 
X 3 HOH 137 537 530  HOH HOH F . 
X 3 HOH 138 538 532  HOH HOH F . 
X 3 HOH 139 539 938  HOH HOH F . 
X 3 HOH 140 540 590  HOH HOH F . 
X 3 HOH 141 541 290  HOH HOH F . 
X 3 HOH 142 542 684  HOH HOH F . 
X 3 HOH 143 543 273  HOH HOH F . 
X 3 HOH 144 544 1055 HOH HOH F . 
X 3 HOH 145 545 915  HOH HOH F . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? '(1.20.1_4487: ???)' 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? v.1.04               2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .                    3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? MOLREP  ? ? ? .                    4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   109.75 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9KHO 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     78.098 
_cell.length_a_esd                 ? 
_cell.length_b                     149.830 
_cell.length_b_esd                 ? 
_cell.length_c                     80.184 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        12 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9KHO 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9KHO 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.52 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          51.16 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              6.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.2 M sodium nitrate, 0.1 M Bis-Tris propane (pH 6.5), and 20% w/v polyethylene glycol 3350' 
_exptl_crystal_grow.pdbx_pH_range   5.5-6.5 
_exptl_crystal_grow.temp            298 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-09-15 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97923 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL19U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97923 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL19U1 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9KHO 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.16 
_reflns.d_resolution_low                               19.97 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     92605 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.80 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.7 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          13.8 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.083 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.16 
_reflns_shell.d_res_low                                     2.24 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             92605 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.083 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9KHO 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.16 
_refine.ls_d_res_low                             19.97 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     92569 
_refine.ls_number_reflns_R_free                  2010 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.95 
_refine.ls_percent_reflns_R_free                 2.17 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1847 
_refine.ls_R_factor_R_free                       0.2245 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1838 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.10 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 24.59 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.29 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        11969 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         12 
_refine_hist.number_atoms_solvent             1009 
_refine_hist.number_atoms_total               12990 
_refine_hist.d_res_high                       2.16 
_refine_hist.d_res_low                        19.97 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.007 ? ?    ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.882 ? ?    ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 6.482 ? 1664 ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.054 ? 1783 ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.007 ? 2183 ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.16 2.21  . . 149 6424 100.00 . . . . 0.2708 . . . . . . . . . . . 0.3271 
'X-RAY DIFFRACTION' 2.21 2.27  . . 142 6444 100.00 . . . . 0.2621 . . . . . . . . . . . 0.2877 
'X-RAY DIFFRACTION' 2.27 2.34  . . 145 6454 100.00 . . . . 0.2436 . . . . . . . . . . . 0.3369 
'X-RAY DIFFRACTION' 2.34 2.42  . . 144 6440 100.00 . . . . 0.2289 . . . . . . . . . . . 0.2927 
'X-RAY DIFFRACTION' 2.42 2.50  . . 133 6487 100.00 . . . . 0.2177 . . . . . . . . . . . 0.2689 
'X-RAY DIFFRACTION' 2.50 2.60  . . 148 6460 100.00 . . . . 0.2070 . . . . . . . . . . . 0.2577 
'X-RAY DIFFRACTION' 2.60 2.72  . . 141 6437 100.00 . . . . 0.2039 . . . . . . . . . . . 0.2597 
'X-RAY DIFFRACTION' 2.72 2.86  . . 146 6490 100.00 . . . . 0.2027 . . . . . . . . . . . 0.2890 
'X-RAY DIFFRACTION' 2.86 3.04  . . 141 6430 100.00 . . . . 0.1960 . . . . . . . . . . . 0.2179 
'X-RAY DIFFRACTION' 3.04 3.28  . . 148 6476 100.00 . . . . 0.1922 . . . . . . . . . . . 0.2459 
'X-RAY DIFFRACTION' 3.28 3.60  . . 142 6478 100.00 . . . . 0.1707 . . . . . . . . . . . 0.2158 
'X-RAY DIFFRACTION' 3.60 4.12  . . 141 6495 100.00 . . . . 0.1530 . . . . . . . . . . . 0.1961 
'X-RAY DIFFRACTION' 4.12 5.18  . . 139 6494 100.00 . . . . 0.1411 . . . . . . . . . . . 0.1629 
'X-RAY DIFFRACTION' 5.18 19.97 . . 151 6550 100.00 . . . . 0.1702 . . . . . . . . . . . 0.1849 
# 
_struct.entry_id                     9KHO 
_struct.title                        'Crystal structure of N-acyl homoserine lactonase AhlX mutant M41(E77I/D177G/T243Y/H255L)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9KHO 
_struct_keywords.text            'Lactonase, Quorum sensing, Quorum quenching, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 1 ? 
F N N 1 ? 
G N N 2 ? 
H N N 2 ? 
I N N 2 ? 
J N N 2 ? 
K N N 2 ? 
L N N 2 ? 
M N N 2 ? 
N N N 2 ? 
O N N 2 ? 
P N N 2 ? 
Q N N 2 ? 
R N N 2 ? 
S N N 3 ? 
T N N 3 ? 
U N N 3 ? 
V N N 3 ? 
W N N 3 ? 
X N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A455K4F1_9GAMM 
_struct_ref.pdbx_db_accession          A0A455K4F1 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MAAPRLYMFQTGTLKCRVCNIKMNAGLDDYEIPVPWYLITHPKGNVVIDGGCAVECASDPKGYWGDITSVYWPVMREEEG
CVQALKAFGIEPADVRYVLHSHLHLDHTGATGRFPNAIHIVRRCEYEYAMAPDWFSAGGYIRADFDRPDVKWHLLEDHDD
GYDVFGDDTIRFIFTPGHAPGHSSFLLRLPETGPVLLAVDAAYTTDHWDEKALPGFLASTVDAVRSVRKLHALAEKTGAL
VVTGHDPEAWPTFRHAPEYYA
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9KHO A 1 ? 261 ? A0A455K4F1 1 ? 261 ? 1 261 
2 1 9KHO B 1 ? 261 ? A0A455K4F1 1 ? 261 ? 1 261 
3 1 9KHO C 1 ? 261 ? A0A455K4F1 1 ? 261 ? 1 261 
4 1 9KHO D 1 ? 261 ? A0A455K4F1 1 ? 261 ? 1 261 
5 1 9KHO E 1 ? 261 ? A0A455K4F1 1 ? 261 ? 1 261 
6 1 9KHO F 1 ? 261 ? A0A455K4F1 1 ? 261 ? 1 261 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9KHO ILE A 77  ? UNP A0A455K4F1 GLU 77  'engineered mutation' 77  1  
1 9KHO GLY A 157 ? UNP A0A455K4F1 ASP 157 'engineered mutation' 157 2  
1 9KHO TYR A 243 ? UNP A0A455K4F1 THR 243 'engineered mutation' 243 3  
1 9KHO LEU A 255 ? UNP A0A455K4F1 HIS 255 'engineered mutation' 255 4  
2 9KHO ILE B 77  ? UNP A0A455K4F1 GLU 77  'engineered mutation' 77  5  
2 9KHO GLY B 157 ? UNP A0A455K4F1 ASP 157 'engineered mutation' 157 6  
2 9KHO TYR B 243 ? UNP A0A455K4F1 THR 243 'engineered mutation' 243 7  
2 9KHO LEU B 255 ? UNP A0A455K4F1 HIS 255 'engineered mutation' 255 8  
3 9KHO ILE C 77  ? UNP A0A455K4F1 GLU 77  'engineered mutation' 77  9  
3 9KHO GLY C 157 ? UNP A0A455K4F1 ASP 157 'engineered mutation' 157 10 
3 9KHO TYR C 243 ? UNP A0A455K4F1 THR 243 'engineered mutation' 243 11 
3 9KHO LEU C 255 ? UNP A0A455K4F1 HIS 255 'engineered mutation' 255 12 
4 9KHO ILE D 77  ? UNP A0A455K4F1 GLU 77  'engineered mutation' 77  13 
4 9KHO GLY D 157 ? UNP A0A455K4F1 ASP 157 'engineered mutation' 157 14 
4 9KHO TYR D 243 ? UNP A0A455K4F1 THR 243 'engineered mutation' 243 15 
4 9KHO LEU D 255 ? UNP A0A455K4F1 HIS 255 'engineered mutation' 255 16 
5 9KHO ILE E 77  ? UNP A0A455K4F1 GLU 77  'engineered mutation' 77  17 
5 9KHO GLY E 157 ? UNP A0A455K4F1 ASP 157 'engineered mutation' 157 18 
5 9KHO TYR E 243 ? UNP A0A455K4F1 THR 243 'engineered mutation' 243 19 
5 9KHO LEU E 255 ? UNP A0A455K4F1 HIS 255 'engineered mutation' 255 20 
6 9KHO ILE F 77  ? UNP A0A455K4F1 GLU 77  'engineered mutation' 77  21 
6 9KHO GLY F 157 ? UNP A0A455K4F1 ASP 157 'engineered mutation' 157 22 
6 9KHO TYR F 243 ? UNP A0A455K4F1 THR 243 'engineered mutation' 243 23 
6 9KHO LEU F 255 ? UNP A0A455K4F1 HIS 255 'engineered mutation' 255 24 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   hexameric 
_pdbx_struct_assembly.oligomeric_count     6 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'native gel electrophoresis' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 VAL A 18  ? LYS A 22  ? VAL A 18  LYS A 22  1 ? 5  
HELX_P HELX_P2  AA2 VAL A 54  ? ASP A 59  ? VAL A 54  ASP A 59  1 ? 6  
HELX_P HELX_P3  AA3 ASP A 59  ? GLY A 65  ? ASP A 59  GLY A 65  1 ? 7  
HELX_P HELX_P4  AA4 ASP A 66  ? VAL A 70  ? ASP A 66  VAL A 70  5 ? 5  
HELX_P HELX_P5  AA5 ARG A 76  ? GLU A 79  ? ARG A 76  GLU A 79  5 ? 4  
HELX_P HELX_P6  AA6 GLY A 80  ? GLY A 89  ? GLY A 80  GLY A 89  1 ? 10 
HELX_P HELX_P7  AA7 GLU A 91  ? VAL A 95  ? GLU A 91  VAL A 95  5 ? 5  
HELX_P HELX_P8  AA8 ARG A 123 ? ALA A 131 ? ARG A 123 ALA A 131 1 ? 9  
HELX_P HELX_P9  AA9 ASP A 133 ? GLY A 138 ? ASP A 133 GLY A 138 1 ? 6  
HELX_P HELX_P10 AB1 ILE A 141 ? ASP A 146 ? ILE A 141 ASP A 146 1 ? 6  
HELX_P HELX_P11 AB2 GLU A 156 ? ASP A 160 ? GLU A 156 ASP A 160 5 ? 5  
HELX_P HELX_P12 AB3 ASP A 200 ? ALA A 202 ? ASP A 200 ALA A 202 5 ? 3  
HELX_P HELX_P13 AB4 THR A 204 ? ASP A 209 ? THR A 204 ASP A 209 1 ? 6  
HELX_P HELX_P14 AB5 SER A 219 ? GLY A 238 ? SER A 219 GLY A 238 1 ? 20 
HELX_P HELX_P15 AB6 ALA A 249 ? PHE A 253 ? ALA A 249 PHE A 253 5 ? 5  
HELX_P HELX_P16 AB7 VAL B 54  ? ASP B 59  ? VAL B 54  ASP B 59  1 ? 6  
HELX_P HELX_P17 AB8 ASP B 59  ? GLY B 65  ? ASP B 59  GLY B 65  1 ? 7  
HELX_P HELX_P18 AB9 ASP B 66  ? VAL B 70  ? ASP B 66  VAL B 70  5 ? 5  
HELX_P HELX_P19 AC1 ARG B 76  ? GLU B 79  ? ARG B 76  GLU B 79  5 ? 4  
HELX_P HELX_P20 AC2 GLY B 80  ? GLY B 89  ? GLY B 80  GLY B 89  1 ? 10 
HELX_P HELX_P21 AC3 GLU B 91  ? ALA B 93  ? GLU B 91  ALA B 93  5 ? 3  
HELX_P HELX_P22 AC4 HIS B 104 ? THR B 108 ? HIS B 104 THR B 108 5 ? 5  
HELX_P HELX_P23 AC5 ARG B 123 ? ALA B 131 ? ARG B 123 ALA B 131 1 ? 9  
HELX_P HELX_P24 AC6 ASP B 133 ? GLY B 138 ? ASP B 133 GLY B 138 1 ? 6  
HELX_P HELX_P25 AC7 ILE B 141 ? ASP B 146 ? ILE B 141 ASP B 146 1 ? 6  
HELX_P HELX_P26 AC8 GLU B 156 ? ASP B 160 ? GLU B 156 ASP B 160 5 ? 5  
HELX_P HELX_P27 AC9 ASP B 200 ? ALA B 202 ? ASP B 200 ALA B 202 5 ? 3  
HELX_P HELX_P28 AD1 THR B 204 ? ASP B 209 ? THR B 204 ASP B 209 1 ? 6  
HELX_P HELX_P29 AD2 SER B 219 ? GLY B 238 ? SER B 219 GLY B 238 1 ? 20 
HELX_P HELX_P30 AD3 ALA B 249 ? PHE B 253 ? ALA B 249 PHE B 253 5 ? 5  
HELX_P HELX_P31 AD4 CYS C 19  ? ILE C 21  ? CYS C 19  ILE C 21  5 ? 3  
HELX_P HELX_P32 AD5 ALA C 53  ? SER C 58  ? ALA C 53  SER C 58  5 ? 6  
HELX_P HELX_P33 AD6 ASP C 59  ? GLY C 65  ? ASP C 59  GLY C 65  1 ? 7  
HELX_P HELX_P34 AD7 ASP C 66  ? VAL C 70  ? ASP C 66  VAL C 70  5 ? 5  
HELX_P HELX_P35 AD8 ARG C 76  ? GLU C 79  ? ARG C 76  GLU C 79  5 ? 4  
HELX_P HELX_P36 AD9 GLY C 80  ? GLY C 89  ? GLY C 80  GLY C 89  1 ? 10 
HELX_P HELX_P37 AE1 GLU C 91  ? VAL C 95  ? GLU C 91  VAL C 95  5 ? 5  
HELX_P HELX_P38 AE2 HIS C 104 ? THR C 108 ? HIS C 104 THR C 108 5 ? 5  
HELX_P HELX_P39 AE3 ARG C 123 ? ALA C 131 ? ARG C 123 ALA C 131 1 ? 9  
HELX_P HELX_P40 AE4 SER C 136 ? TYR C 140 ? SER C 136 TYR C 140 5 ? 5  
HELX_P HELX_P41 AE5 ILE C 141 ? ASP C 146 ? ILE C 141 ASP C 146 1 ? 6  
HELX_P HELX_P42 AE6 GLU C 156 ? ASP C 160 ? GLU C 156 ASP C 160 5 ? 5  
HELX_P HELX_P43 AE7 ASP C 200 ? ALA C 202 ? ASP C 200 ALA C 202 5 ? 3  
HELX_P HELX_P44 AE8 THR C 204 ? ASP C 209 ? THR C 204 ASP C 209 1 ? 6  
HELX_P HELX_P45 AE9 SER C 219 ? GLY C 238 ? SER C 219 GLY C 238 1 ? 20 
HELX_P HELX_P46 AF1 ALA C 249 ? PHE C 253 ? ALA C 249 PHE C 253 5 ? 5  
HELX_P HELX_P47 AF2 VAL D 18  ? LYS D 22  ? VAL D 18  LYS D 22  1 ? 5  
HELX_P HELX_P48 AF3 ALA D 53  ? SER D 58  ? ALA D 53  SER D 58  5 ? 6  
HELX_P HELX_P49 AF4 ASP D 59  ? TRP D 64  ? ASP D 59  TRP D 64  1 ? 6  
HELX_P HELX_P50 AF5 GLY D 65  ? VAL D 70  ? GLY D 65  VAL D 70  5 ? 6  
HELX_P HELX_P51 AF6 ARG D 76  ? GLU D 79  ? ARG D 76  GLU D 79  5 ? 4  
HELX_P HELX_P52 AF7 GLY D 80  ? GLY D 89  ? GLY D 80  GLY D 89  1 ? 10 
HELX_P HELX_P53 AF8 GLU D 91  ? ALA D 93  ? GLU D 91  ALA D 93  5 ? 3  
HELX_P HELX_P54 AF9 HIS D 104 ? THR D 108 ? HIS D 104 THR D 108 5 ? 5  
HELX_P HELX_P55 AG1 ARG D 123 ? ALA D 131 ? ARG D 123 ALA D 131 1 ? 9  
HELX_P HELX_P56 AG2 ASP D 133 ? GLY D 138 ? ASP D 133 GLY D 138 1 ? 6  
HELX_P HELX_P57 AG3 ILE D 141 ? ASP D 146 ? ILE D 141 ASP D 146 1 ? 6  
HELX_P HELX_P58 AG4 GLU D 156 ? ASP D 160 ? GLU D 156 ASP D 160 5 ? 5  
HELX_P HELX_P59 AG5 ASP D 200 ? ALA D 202 ? ASP D 200 ALA D 202 5 ? 3  
HELX_P HELX_P60 AG6 THR D 204 ? ASP D 209 ? THR D 204 ASP D 209 1 ? 6  
HELX_P HELX_P61 AG7 SER D 219 ? GLY D 238 ? SER D 219 GLY D 238 1 ? 20 
HELX_P HELX_P62 AG8 ALA D 249 ? PHE D 253 ? ALA D 249 PHE D 253 5 ? 5  
HELX_P HELX_P63 AG9 VAL E 18  ? LYS E 22  ? VAL E 18  LYS E 22  1 ? 5  
HELX_P HELX_P64 AH1 VAL E 54  ? ASP E 59  ? VAL E 54  ASP E 59  1 ? 6  
HELX_P HELX_P65 AH2 ASP E 59  ? GLY E 65  ? ASP E 59  GLY E 65  1 ? 7  
HELX_P HELX_P66 AH3 ASP E 66  ? VAL E 70  ? ASP E 66  VAL E 70  5 ? 5  
HELX_P HELX_P67 AH4 ARG E 76  ? GLU E 79  ? ARG E 76  GLU E 79  5 ? 4  
HELX_P HELX_P68 AH5 GLY E 80  ? ALA E 87  ? GLY E 80  ALA E 87  1 ? 8  
HELX_P HELX_P69 AH6 GLU E 91  ? VAL E 95  ? GLU E 91  VAL E 95  5 ? 5  
HELX_P HELX_P70 AH7 HIS E 104 ? THR E 108 ? HIS E 104 THR E 108 5 ? 5  
HELX_P HELX_P71 AH8 ARG E 123 ? ALA E 131 ? ARG E 123 ALA E 131 1 ? 9  
HELX_P HELX_P72 AH9 ASP E 133 ? GLY E 138 ? ASP E 133 GLY E 138 1 ? 6  
HELX_P HELX_P73 AI1 ILE E 141 ? ASP E 146 ? ILE E 141 ASP E 146 1 ? 6  
HELX_P HELX_P74 AI2 GLU E 156 ? ASP E 160 ? GLU E 156 ASP E 160 5 ? 5  
HELX_P HELX_P75 AI3 ASP E 200 ? ALA E 202 ? ASP E 200 ALA E 202 5 ? 3  
HELX_P HELX_P76 AI4 THR E 204 ? ASP E 209 ? THR E 204 ASP E 209 1 ? 6  
HELX_P HELX_P77 AI5 SER E 219 ? GLY E 238 ? SER E 219 GLY E 238 1 ? 20 
HELX_P HELX_P78 AI6 ALA E 249 ? PHE E 253 ? ALA E 249 PHE E 253 5 ? 5  
HELX_P HELX_P79 AI7 CYS F 19  ? ILE F 21  ? CYS F 19  ILE F 21  5 ? 3  
HELX_P HELX_P80 AI8 VAL F 54  ? ASP F 59  ? VAL F 54  ASP F 59  1 ? 6  
HELX_P HELX_P81 AI9 ASP F 59  ? GLY F 65  ? ASP F 59  GLY F 65  1 ? 7  
HELX_P HELX_P82 AJ1 ASP F 66  ? VAL F 70  ? ASP F 66  VAL F 70  5 ? 5  
HELX_P HELX_P83 AJ2 ARG F 76  ? GLU F 79  ? ARG F 76  GLU F 79  5 ? 4  
HELX_P HELX_P84 AJ3 GLY F 80  ? ALA F 87  ? GLY F 80  ALA F 87  1 ? 8  
HELX_P HELX_P85 AJ4 GLU F 91  ? VAL F 95  ? GLU F 91  VAL F 95  5 ? 5  
HELX_P HELX_P86 AJ5 HIS F 104 ? THR F 108 ? HIS F 104 THR F 108 5 ? 5  
HELX_P HELX_P87 AJ6 ARG F 123 ? ALA F 131 ? ARG F 123 ALA F 131 1 ? 9  
HELX_P HELX_P88 AJ7 ASP F 133 ? GLY F 138 ? ASP F 133 GLY F 138 1 ? 6  
HELX_P HELX_P89 AJ8 ILE F 141 ? ASP F 146 ? ILE F 141 ASP F 146 1 ? 6  
HELX_P HELX_P90 AJ9 GLU F 156 ? ASP F 160 ? GLU F 156 ASP F 160 5 ? 5  
HELX_P HELX_P91 AK1 ASP F 200 ? ALA F 202 ? ASP F 200 ALA F 202 5 ? 3  
HELX_P HELX_P92 AK2 THR F 204 ? ASP F 209 ? THR F 204 ASP F 209 1 ? 6  
HELX_P HELX_P93 AK3 SER F 219 ? GLY F 238 ? SER F 219 GLY F 238 1 ? 20 
HELX_P HELX_P94 AK4 ALA F 249 ? PHE F 253 ? ALA F 249 PHE F 253 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A HIS 102 NE2 ? ? ? 1_555 G NI  . NI ? ? A HIS 102 A NI  301 1_555 ? ? ? ? ? ? ? 2.396 ? ? 
metalc2  metalc ? ? A HIS 104 ND1 ? ? ? 1_555 G NI  . NI ? ? A HIS 104 A NI  301 1_555 ? ? ? ? ? ? ? 2.432 ? ? 
metalc3  metalc ? ? A ASP 106 OD2 ? ? ? 1_555 H NI  . NI ? ? A ASP 106 A NI  302 1_555 ? ? ? ? ? ? ? 2.344 ? ? 
metalc4  metalc ? ? A HIS 107 NE2 ? ? ? 1_555 H NI  . NI ? ? A HIS 107 A NI  302 1_555 ? ? ? ? ? ? ? 2.259 ? ? 
metalc5  metalc ? ? A HIS 178 NE2 ? ? ? 1_555 G NI  . NI ? ? A HIS 178 A NI  301 1_555 ? ? ? ? ? ? ? 2.155 ? ? 
metalc6  metalc ? ? A ASP 200 OD2 ? ? ? 1_555 G NI  . NI ? ? A ASP 200 A NI  301 1_555 ? ? ? ? ? ? ? 2.403 ? ? 
metalc7  metalc ? ? A ASP 200 OD2 ? ? ? 1_555 H NI  . NI ? ? A ASP 200 A NI  302 1_555 ? ? ? ? ? ? ? 2.262 ? ? 
metalc8  metalc ? ? A HIS 245 NE2 ? ? ? 1_555 H NI  . NI ? ? A HIS 245 A NI  302 1_555 ? ? ? ? ? ? ? 2.347 ? ? 
metalc9  metalc ? ? G NI  .   NI  ? ? ? 1_555 S HOH . O  ? ? A NI  301 A HOH 412 1_555 ? ? ? ? ? ? ? 2.689 ? ? 
metalc10 metalc ? ? B HIS 102 NE2 ? ? ? 1_555 I NI  . NI ? ? B HIS 102 B NI  301 1_555 ? ? ? ? ? ? ? 2.415 ? ? 
metalc11 metalc ? ? B HIS 104 ND1 ? ? ? 1_555 I NI  . NI ? ? B HIS 104 B NI  301 1_555 ? ? ? ? ? ? ? 2.518 ? ? 
metalc12 metalc ? ? B ASP 106 OD2 ? ? ? 1_555 J NI  . NI ? ? B ASP 106 B NI  302 1_555 ? ? ? ? ? ? ? 2.140 ? ? 
metalc13 metalc ? ? B HIS 107 NE2 ? ? ? 1_555 J NI  . NI ? ? B HIS 107 B NI  302 1_555 ? ? ? ? ? ? ? 2.089 ? ? 
metalc14 metalc ? ? B HIS 178 NE2 ? ? ? 1_555 I NI  . NI ? ? B HIS 178 B NI  301 1_555 ? ? ? ? ? ? ? 2.064 ? ? 
metalc15 metalc ? ? B ASP 200 OD2 ? ? ? 1_555 I NI  . NI ? ? B ASP 200 B NI  301 1_555 ? ? ? ? ? ? ? 2.381 ? ? 
metalc16 metalc ? ? B ASP 200 OD2 ? ? ? 1_555 J NI  . NI ? ? B ASP 200 B NI  302 1_555 ? ? ? ? ? ? ? 2.322 ? ? 
metalc17 metalc ? ? B HIS 245 NE2 ? ? ? 1_555 J NI  . NI ? ? B HIS 245 B NI  302 1_555 ? ? ? ? ? ? ? 2.311 ? ? 
metalc18 metalc ? ? C HIS 102 NE2 ? ? ? 1_555 K NI  . NI ? ? C HIS 102 C NI  301 1_555 ? ? ? ? ? ? ? 2.464 ? ? 
metalc19 metalc ? ? C HIS 104 ND1 ? ? ? 1_555 K NI  . NI ? ? C HIS 104 C NI  301 1_555 ? ? ? ? ? ? ? 2.394 ? ? 
metalc20 metalc ? ? C ASP 106 OD2 ? ? ? 1_555 L NI  . NI ? ? C ASP 106 C NI  302 1_555 ? ? ? ? ? ? ? 2.351 ? ? 
metalc21 metalc ? ? C HIS 107 NE2 ? ? ? 1_555 L NI  . NI ? ? C HIS 107 C NI  302 1_555 ? ? ? ? ? ? ? 2.248 ? ? 
metalc22 metalc ? ? C HIS 178 NE2 ? ? ? 1_555 K NI  . NI ? ? C HIS 178 C NI  301 1_555 ? ? ? ? ? ? ? 2.126 ? ? 
metalc23 metalc ? ? C ASP 200 OD2 ? ? ? 1_555 K NI  . NI ? ? C ASP 200 C NI  301 1_555 ? ? ? ? ? ? ? 2.337 ? ? 
metalc24 metalc ? ? C ASP 200 OD2 ? ? ? 1_555 L NI  . NI ? ? C ASP 200 C NI  302 1_555 ? ? ? ? ? ? ? 2.236 ? ? 
metalc25 metalc ? ? C HIS 245 NE2 ? ? ? 1_555 L NI  . NI ? ? C HIS 245 C NI  302 1_555 ? ? ? ? ? ? ? 2.187 ? ? 
metalc26 metalc ? ? K NI  .   NI  ? ? ? 1_555 U HOH . O  ? ? C NI  301 C HOH 401 1_555 ? ? ? ? ? ? ? 2.418 ? ? 
metalc27 metalc ? ? L NI  .   NI  ? ? ? 1_555 U HOH . O  ? ? C NI  302 C HOH 401 1_555 ? ? ? ? ? ? ? 2.523 ? ? 
metalc28 metalc ? ? D HIS 102 NE2 ? ? ? 1_555 N NI  . NI ? ? D HIS 102 D NI  302 1_555 ? ? ? ? ? ? ? 2.336 ? ? 
metalc29 metalc ? ? D HIS 104 ND1 ? ? ? 1_555 N NI  . NI ? ? D HIS 104 D NI  302 1_555 ? ? ? ? ? ? ? 2.342 ? ? 
metalc30 metalc ? ? D ASP 106 OD2 ? ? ? 1_555 M NI  . NI ? ? D ASP 106 D NI  301 1_555 ? ? ? ? ? ? ? 2.307 ? ? 
metalc31 metalc ? ? D HIS 107 NE2 ? ? ? 1_555 M NI  . NI ? ? D HIS 107 D NI  301 1_555 ? ? ? ? ? ? ? 2.245 ? ? 
metalc32 metalc ? ? D ASP 200 OD2 ? ? ? 1_555 M NI  . NI ? ? D ASP 200 D NI  301 1_555 ? ? ? ? ? ? ? 2.431 ? ? 
metalc33 metalc ? ? D ASP 200 OD2 ? ? ? 1_555 N NI  . NI ? ? D ASP 200 D NI  302 1_555 ? ? ? ? ? ? ? 2.444 ? ? 
metalc34 metalc ? ? D HIS 245 NE2 ? ? ? 1_555 M NI  . NI ? ? D HIS 245 D NI  301 1_555 ? ? ? ? ? ? ? 2.332 ? ? 
metalc35 metalc ? ? E HIS 102 NE2 ? ? ? 1_555 O NI  . NI ? ? E HIS 102 E NI  301 1_555 ? ? ? ? ? ? ? 2.337 ? ? 
metalc36 metalc ? ? E HIS 104 ND1 ? ? ? 1_555 O NI  . NI ? ? E HIS 104 E NI  301 1_555 ? ? ? ? ? ? ? 2.364 ? ? 
metalc37 metalc ? ? E ASP 106 OD2 ? ? ? 1_555 P NI  . NI ? ? E ASP 106 E NI  302 1_555 ? ? ? ? ? ? ? 2.327 ? ? 
metalc38 metalc ? ? E HIS 107 NE2 ? ? ? 1_555 P NI  . NI ? ? E HIS 107 E NI  302 1_555 ? ? ? ? ? ? ? 2.237 ? ? 
metalc39 metalc ? ? E HIS 178 NE2 ? ? ? 1_555 O NI  . NI ? ? E HIS 178 E NI  301 1_555 ? ? ? ? ? ? ? 2.045 ? ? 
metalc40 metalc ? ? E ASP 200 OD2 ? ? ? 1_555 O NI  . NI ? ? E ASP 200 E NI  301 1_555 ? ? ? ? ? ? ? 2.439 ? ? 
metalc41 metalc ? ? E ASP 200 OD2 ? ? ? 1_555 P NI  . NI ? ? E ASP 200 E NI  302 1_555 ? ? ? ? ? ? ? 2.269 ? ? 
metalc42 metalc ? ? E HIS 245 NE2 ? ? ? 1_555 P NI  . NI ? ? E HIS 245 E NI  302 1_555 ? ? ? ? ? ? ? 2.270 ? ? 
metalc43 metalc ? ? O NI  .   NI  ? ? ? 1_555 W HOH . O  ? ? E NI  301 E HOH 426 1_555 ? ? ? ? ? ? ? 2.611 ? ? 
metalc44 metalc ? ? F HIS 102 NE2 ? ? ? 1_555 Q NI  . NI ? ? F HIS 102 F NI  301 1_555 ? ? ? ? ? ? ? 2.255 ? ? 
metalc45 metalc ? ? F HIS 104 ND1 ? ? ? 1_555 Q NI  . NI ? ? F HIS 104 F NI  301 1_555 ? ? ? ? ? ? ? 2.405 ? ? 
metalc46 metalc ? ? F ASP 106 OD2 ? ? ? 1_555 R NI  . NI ? ? F ASP 106 F NI  302 1_555 ? ? ? ? ? ? ? 2.324 ? ? 
metalc47 metalc ? ? F HIS 107 NE2 ? ? ? 1_555 R NI  . NI ? ? F HIS 107 F NI  302 1_555 ? ? ? ? ? ? ? 2.331 ? ? 
metalc48 metalc ? ? F HIS 178 NE2 ? ? ? 1_555 Q NI  . NI ? ? F HIS 178 F NI  301 1_555 ? ? ? ? ? ? ? 2.189 ? ? 
metalc49 metalc ? ? F ASP 200 OD2 ? ? ? 1_555 Q NI  . NI ? ? F ASP 200 F NI  301 1_555 ? ? ? ? ? ? ? 2.337 ? ? 
metalc50 metalc ? ? F ASP 200 OD2 ? ? ? 1_555 R NI  . NI ? ? F ASP 200 F NI  302 1_555 ? ? ? ? ? ? ? 2.292 ? ? 
metalc51 metalc ? ? F HIS 245 NE2 ? ? ? 1_555 R NI  . NI ? ? F HIS 245 F NI  302 1_555 ? ? ? ? ? ? ? 2.347 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  NE2 ? A HIS 102 ? A HIS 102 ? 1_555 NI ? G NI . ? A NI 301 ? 1_555 ND1 ? A HIS 104 ? A HIS 104 ? 1_555 88.3  ? 
2  NE2 ? A HIS 102 ? A HIS 102 ? 1_555 NI ? G NI . ? A NI 301 ? 1_555 NE2 ? A HIS 178 ? A HIS 178 ? 1_555 95.0  ? 
3  ND1 ? A HIS 104 ? A HIS 104 ? 1_555 NI ? G NI . ? A NI 301 ? 1_555 NE2 ? A HIS 178 ? A HIS 178 ? 1_555 86.2  ? 
4  NE2 ? A HIS 102 ? A HIS 102 ? 1_555 NI ? G NI . ? A NI 301 ? 1_555 OD2 ? A ASP 200 ? A ASP 200 ? 1_555 81.0  ? 
5  ND1 ? A HIS 104 ? A HIS 104 ? 1_555 NI ? G NI . ? A NI 301 ? 1_555 OD2 ? A ASP 200 ? A ASP 200 ? 1_555 169.2 ? 
6  NE2 ? A HIS 178 ? A HIS 178 ? 1_555 NI ? G NI . ? A NI 301 ? 1_555 OD2 ? A ASP 200 ? A ASP 200 ? 1_555 93.1  ? 
7  NE2 ? A HIS 102 ? A HIS 102 ? 1_555 NI ? G NI . ? A NI 301 ? 1_555 O   ? S HOH .   ? A HOH 412 ? 1_555 168.6 ? 
8  ND1 ? A HIS 104 ? A HIS 104 ? 1_555 NI ? G NI . ? A NI 301 ? 1_555 O   ? S HOH .   ? A HOH 412 ? 1_555 101.4 ? 
9  NE2 ? A HIS 178 ? A HIS 178 ? 1_555 NI ? G NI . ? A NI 301 ? 1_555 O   ? S HOH .   ? A HOH 412 ? 1_555 91.6  ? 
10 OD2 ? A ASP 200 ? A ASP 200 ? 1_555 NI ? G NI . ? A NI 301 ? 1_555 O   ? S HOH .   ? A HOH 412 ? 1_555 89.5  ? 
11 OD2 ? A ASP 106 ? A ASP 106 ? 1_555 NI ? H NI . ? A NI 302 ? 1_555 NE2 ? A HIS 107 ? A HIS 107 ? 1_555 93.3  ? 
12 OD2 ? A ASP 106 ? A ASP 106 ? 1_555 NI ? H NI . ? A NI 302 ? 1_555 OD2 ? A ASP 200 ? A ASP 200 ? 1_555 169.4 ? 
13 NE2 ? A HIS 107 ? A HIS 107 ? 1_555 NI ? H NI . ? A NI 302 ? 1_555 OD2 ? A ASP 200 ? A ASP 200 ? 1_555 86.5  ? 
14 OD2 ? A ASP 106 ? A ASP 106 ? 1_555 NI ? H NI . ? A NI 302 ? 1_555 NE2 ? A HIS 245 ? A HIS 245 ? 1_555 83.4  ? 
15 NE2 ? A HIS 107 ? A HIS 107 ? 1_555 NI ? H NI . ? A NI 302 ? 1_555 NE2 ? A HIS 245 ? A HIS 245 ? 1_555 104.9 ? 
16 OD2 ? A ASP 200 ? A ASP 200 ? 1_555 NI ? H NI . ? A NI 302 ? 1_555 NE2 ? A HIS 245 ? A HIS 245 ? 1_555 107.0 ? 
17 NE2 ? B HIS 102 ? B HIS 102 ? 1_555 NI ? I NI . ? B NI 301 ? 1_555 ND1 ? B HIS 104 ? B HIS 104 ? 1_555 88.0  ? 
18 NE2 ? B HIS 102 ? B HIS 102 ? 1_555 NI ? I NI . ? B NI 301 ? 1_555 NE2 ? B HIS 178 ? B HIS 178 ? 1_555 94.1  ? 
19 ND1 ? B HIS 104 ? B HIS 104 ? 1_555 NI ? I NI . ? B NI 301 ? 1_555 NE2 ? B HIS 178 ? B HIS 178 ? 1_555 85.5  ? 
20 NE2 ? B HIS 102 ? B HIS 102 ? 1_555 NI ? I NI . ? B NI 301 ? 1_555 OD2 ? B ASP 200 ? B ASP 200 ? 1_555 78.4  ? 
21 ND1 ? B HIS 104 ? B HIS 104 ? 1_555 NI ? I NI . ? B NI 301 ? 1_555 OD2 ? B ASP 200 ? B ASP 200 ? 1_555 165.8 ? 
22 NE2 ? B HIS 178 ? B HIS 178 ? 1_555 NI ? I NI . ? B NI 301 ? 1_555 OD2 ? B ASP 200 ? B ASP 200 ? 1_555 91.2  ? 
23 OD2 ? B ASP 106 ? B ASP 106 ? 1_555 NI ? J NI . ? B NI 302 ? 1_555 NE2 ? B HIS 107 ? B HIS 107 ? 1_555 88.8  ? 
24 OD2 ? B ASP 106 ? B ASP 106 ? 1_555 NI ? J NI . ? B NI 302 ? 1_555 OD2 ? B ASP 200 ? B ASP 200 ? 1_555 167.5 ? 
25 NE2 ? B HIS 107 ? B HIS 107 ? 1_555 NI ? J NI . ? B NI 302 ? 1_555 OD2 ? B ASP 200 ? B ASP 200 ? 1_555 88.1  ? 
26 OD2 ? B ASP 106 ? B ASP 106 ? 1_555 NI ? J NI . ? B NI 302 ? 1_555 NE2 ? B HIS 245 ? B HIS 245 ? 1_555 86.9  ? 
27 NE2 ? B HIS 107 ? B HIS 107 ? 1_555 NI ? J NI . ? B NI 302 ? 1_555 NE2 ? B HIS 245 ? B HIS 245 ? 1_555 113.6 ? 
28 OD2 ? B ASP 200 ? B ASP 200 ? 1_555 NI ? J NI . ? B NI 302 ? 1_555 NE2 ? B HIS 245 ? B HIS 245 ? 1_555 105.5 ? 
29 NE2 ? C HIS 102 ? C HIS 102 ? 1_555 NI ? K NI . ? C NI 301 ? 1_555 ND1 ? C HIS 104 ? C HIS 104 ? 1_555 87.2  ? 
30 NE2 ? C HIS 102 ? C HIS 102 ? 1_555 NI ? K NI . ? C NI 301 ? 1_555 NE2 ? C HIS 178 ? C HIS 178 ? 1_555 97.6  ? 
31 ND1 ? C HIS 104 ? C HIS 104 ? 1_555 NI ? K NI . ? C NI 301 ? 1_555 NE2 ? C HIS 178 ? C HIS 178 ? 1_555 84.6  ? 
32 NE2 ? C HIS 102 ? C HIS 102 ? 1_555 NI ? K NI . ? C NI 301 ? 1_555 OD2 ? C ASP 200 ? C ASP 200 ? 1_555 84.6  ? 
33 ND1 ? C HIS 104 ? C HIS 104 ? 1_555 NI ? K NI . ? C NI 301 ? 1_555 OD2 ? C ASP 200 ? C ASP 200 ? 1_555 171.8 ? 
34 NE2 ? C HIS 178 ? C HIS 178 ? 1_555 NI ? K NI . ? C NI 301 ? 1_555 OD2 ? C ASP 200 ? C ASP 200 ? 1_555 96.4  ? 
35 NE2 ? C HIS 102 ? C HIS 102 ? 1_555 NI ? K NI . ? C NI 301 ? 1_555 O   ? U HOH .   ? C HOH 401 ? 1_555 113.8 ? 
36 ND1 ? C HIS 104 ? C HIS 104 ? 1_555 NI ? K NI . ? C NI 301 ? 1_555 O   ? U HOH .   ? C HOH 401 ? 1_555 96.8  ? 
37 NE2 ? C HIS 178 ? C HIS 178 ? 1_555 NI ? K NI . ? C NI 301 ? 1_555 O   ? U HOH .   ? C HOH 401 ? 1_555 148.6 ? 
38 OD2 ? C ASP 200 ? C ASP 200 ? 1_555 NI ? K NI . ? C NI 301 ? 1_555 O   ? U HOH .   ? C HOH 401 ? 1_555 86.6  ? 
39 OD2 ? C ASP 106 ? C ASP 106 ? 1_555 NI ? L NI . ? C NI 302 ? 1_555 NE2 ? C HIS 107 ? C HIS 107 ? 1_555 88.1  ? 
40 OD2 ? C ASP 106 ? C ASP 106 ? 1_555 NI ? L NI . ? C NI 302 ? 1_555 OD2 ? C ASP 200 ? C ASP 200 ? 1_555 159.6 ? 
41 NE2 ? C HIS 107 ? C HIS 107 ? 1_555 NI ? L NI . ? C NI 302 ? 1_555 OD2 ? C ASP 200 ? C ASP 200 ? 1_555 90.3  ? 
42 OD2 ? C ASP 106 ? C ASP 106 ? 1_555 NI ? L NI . ? C NI 302 ? 1_555 NE2 ? C HIS 245 ? C HIS 245 ? 1_555 90.1  ? 
43 NE2 ? C HIS 107 ? C HIS 107 ? 1_555 NI ? L NI . ? C NI 302 ? 1_555 NE2 ? C HIS 245 ? C HIS 245 ? 1_555 114.0 ? 
44 OD2 ? C ASP 200 ? C ASP 200 ? 1_555 NI ? L NI . ? C NI 302 ? 1_555 NE2 ? C HIS 245 ? C HIS 245 ? 1_555 109.1 ? 
45 OD2 ? C ASP 106 ? C ASP 106 ? 1_555 NI ? L NI . ? C NI 302 ? 1_555 O   ? U HOH .   ? C HOH 401 ? 1_555 73.8  ? 
46 NE2 ? C HIS 107 ? C HIS 107 ? 1_555 NI ? L NI . ? C NI 302 ? 1_555 O   ? U HOH .   ? C HOH 401 ? 1_555 99.2  ? 
47 OD2 ? C ASP 200 ? C ASP 200 ? 1_555 NI ? L NI . ? C NI 302 ? 1_555 O   ? U HOH .   ? C HOH 401 ? 1_555 86.4  ? 
48 NE2 ? C HIS 245 ? C HIS 245 ? 1_555 NI ? L NI . ? C NI 302 ? 1_555 O   ? U HOH .   ? C HOH 401 ? 1_555 142.6 ? 
49 NE2 ? D HIS 102 ? D HIS 102 ? 1_555 NI ? N NI . ? D NI 302 ? 1_555 ND1 ? D HIS 104 ? D HIS 104 ? 1_555 88.6  ? 
50 NE2 ? D HIS 102 ? D HIS 102 ? 1_555 NI ? N NI . ? D NI 302 ? 1_555 OD2 ? D ASP 200 ? D ASP 200 ? 1_555 89.3  ? 
51 ND1 ? D HIS 104 ? D HIS 104 ? 1_555 NI ? N NI . ? D NI 302 ? 1_555 OD2 ? D ASP 200 ? D ASP 200 ? 1_555 177.7 ? 
52 OD2 ? D ASP 106 ? D ASP 106 ? 1_555 NI ? M NI . ? D NI 301 ? 1_555 NE2 ? D HIS 107 ? D HIS 107 ? 1_555 92.6  ? 
53 OD2 ? D ASP 106 ? D ASP 106 ? 1_555 NI ? M NI . ? D NI 301 ? 1_555 OD2 ? D ASP 200 ? D ASP 200 ? 1_555 165.7 ? 
54 NE2 ? D HIS 107 ? D HIS 107 ? 1_555 NI ? M NI . ? D NI 301 ? 1_555 OD2 ? D ASP 200 ? D ASP 200 ? 1_555 95.1  ? 
55 OD2 ? D ASP 106 ? D ASP 106 ? 1_555 NI ? M NI . ? D NI 301 ? 1_555 NE2 ? D HIS 245 ? D HIS 245 ? 1_555 89.5  ? 
56 NE2 ? D HIS 107 ? D HIS 107 ? 1_555 NI ? M NI . ? D NI 301 ? 1_555 NE2 ? D HIS 245 ? D HIS 245 ? 1_555 114.3 ? 
57 OD2 ? D ASP 200 ? D ASP 200 ? 1_555 NI ? M NI . ? D NI 301 ? 1_555 NE2 ? D HIS 245 ? D HIS 245 ? 1_555 98.2  ? 
58 NE2 ? E HIS 102 ? E HIS 102 ? 1_555 NI ? O NI . ? E NI 301 ? 1_555 ND1 ? E HIS 104 ? E HIS 104 ? 1_555 92.9  ? 
59 NE2 ? E HIS 102 ? E HIS 102 ? 1_555 NI ? O NI . ? E NI 301 ? 1_555 NE2 ? E HIS 178 ? E HIS 178 ? 1_555 102.1 ? 
60 ND1 ? E HIS 104 ? E HIS 104 ? 1_555 NI ? O NI . ? E NI 301 ? 1_555 NE2 ? E HIS 178 ? E HIS 178 ? 1_555 87.5  ? 
61 NE2 ? E HIS 102 ? E HIS 102 ? 1_555 NI ? O NI . ? E NI 301 ? 1_555 OD2 ? E ASP 200 ? E ASP 200 ? 1_555 81.8  ? 
62 ND1 ? E HIS 104 ? E HIS 104 ? 1_555 NI ? O NI . ? E NI 301 ? 1_555 OD2 ? E ASP 200 ? E ASP 200 ? 1_555 174.5 ? 
63 NE2 ? E HIS 178 ? E HIS 178 ? 1_555 NI ? O NI . ? E NI 301 ? 1_555 OD2 ? E ASP 200 ? E ASP 200 ? 1_555 92.0  ? 
64 NE2 ? E HIS 102 ? E HIS 102 ? 1_555 NI ? O NI . ? E NI 301 ? 1_555 O   ? W HOH .   ? E HOH 426 ? 1_555 164.4 ? 
65 ND1 ? E HIS 104 ? E HIS 104 ? 1_555 NI ? O NI . ? E NI 301 ? 1_555 O   ? W HOH .   ? E HOH 426 ? 1_555 99.2  ? 
66 NE2 ? E HIS 178 ? E HIS 178 ? 1_555 NI ? O NI . ? E NI 301 ? 1_555 O   ? W HOH .   ? E HOH 426 ? 1_555 88.4  ? 
67 OD2 ? E ASP 200 ? E ASP 200 ? 1_555 NI ? O NI . ? E NI 301 ? 1_555 O   ? W HOH .   ? E HOH 426 ? 1_555 86.3  ? 
68 OD2 ? E ASP 106 ? E ASP 106 ? 1_555 NI ? P NI . ? E NI 302 ? 1_555 NE2 ? E HIS 107 ? E HIS 107 ? 1_555 86.0  ? 
69 OD2 ? E ASP 106 ? E ASP 106 ? 1_555 NI ? P NI . ? E NI 302 ? 1_555 OD2 ? E ASP 200 ? E ASP 200 ? 1_555 168.2 ? 
70 NE2 ? E HIS 107 ? E HIS 107 ? 1_555 NI ? P NI . ? E NI 302 ? 1_555 OD2 ? E ASP 200 ? E ASP 200 ? 1_555 90.1  ? 
71 OD2 ? E ASP 106 ? E ASP 106 ? 1_555 NI ? P NI . ? E NI 302 ? 1_555 NE2 ? E HIS 245 ? E HIS 245 ? 1_555 88.4  ? 
72 NE2 ? E HIS 107 ? E HIS 107 ? 1_555 NI ? P NI . ? E NI 302 ? 1_555 NE2 ? E HIS 245 ? E HIS 245 ? 1_555 111.9 ? 
73 OD2 ? E ASP 200 ? E ASP 200 ? 1_555 NI ? P NI . ? E NI 302 ? 1_555 NE2 ? E HIS 245 ? E HIS 245 ? 1_555 103.4 ? 
74 NE2 ? F HIS 102 ? F HIS 102 ? 1_555 NI ? Q NI . ? F NI 301 ? 1_555 ND1 ? F HIS 104 ? F HIS 104 ? 1_555 93.0  ? 
75 NE2 ? F HIS 102 ? F HIS 102 ? 1_555 NI ? Q NI . ? F NI 301 ? 1_555 NE2 ? F HIS 178 ? F HIS 178 ? 1_555 99.5  ? 
76 ND1 ? F HIS 104 ? F HIS 104 ? 1_555 NI ? Q NI . ? F NI 301 ? 1_555 NE2 ? F HIS 178 ? F HIS 178 ? 1_555 88.7  ? 
77 NE2 ? F HIS 102 ? F HIS 102 ? 1_555 NI ? Q NI . ? F NI 301 ? 1_555 OD2 ? F ASP 200 ? F ASP 200 ? 1_555 91.1  ? 
78 ND1 ? F HIS 104 ? F HIS 104 ? 1_555 NI ? Q NI . ? F NI 301 ? 1_555 OD2 ? F ASP 200 ? F ASP 200 ? 1_555 171.8 ? 
79 NE2 ? F HIS 178 ? F HIS 178 ? 1_555 NI ? Q NI . ? F NI 301 ? 1_555 OD2 ? F ASP 200 ? F ASP 200 ? 1_555 83.6  ? 
80 OD2 ? F ASP 106 ? F ASP 106 ? 1_555 NI ? R NI . ? F NI 302 ? 1_555 NE2 ? F HIS 107 ? F HIS 107 ? 1_555 92.8  ? 
81 OD2 ? F ASP 106 ? F ASP 106 ? 1_555 NI ? R NI . ? F NI 302 ? 1_555 OD2 ? F ASP 200 ? F ASP 200 ? 1_555 158.8 ? 
82 NE2 ? F HIS 107 ? F HIS 107 ? 1_555 NI ? R NI . ? F NI 302 ? 1_555 OD2 ? F ASP 200 ? F ASP 200 ? 1_555 96.3  ? 
83 OD2 ? F ASP 106 ? F ASP 106 ? 1_555 NI ? R NI . ? F NI 302 ? 1_555 NE2 ? F HIS 245 ? F HIS 245 ? 1_555 84.8  ? 
84 NE2 ? F HIS 107 ? F HIS 107 ? 1_555 NI ? R NI . ? F NI 302 ? 1_555 NE2 ? F HIS 245 ? F HIS 245 ? 1_555 105.3 ? 
85 OD2 ? F ASP 200 ? F ASP 200 ? 1_555 NI ? R NI . ? F NI 302 ? 1_555 NE2 ? F HIS 245 ? F HIS 245 ? 1_555 111.0 ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 4 ? 
AA3 ? 7 ? 
AA4 ? 4 ? 
AA5 ? 7 ? 
AA6 ? 4 ? 
AA7 ? 7 ? 
AA8 ? 4 ? 
AA9 ? 7 ? 
AB1 ? 4 ? 
AB2 ? 7 ? 
AB3 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA1 6 7 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? parallel      
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? parallel      
AA3 5 6 ? parallel      
AA3 6 7 ? parallel      
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? parallel      
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? parallel      
AA5 5 6 ? parallel      
AA5 6 7 ? parallel      
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? parallel      
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA7 4 5 ? parallel      
AA7 5 6 ? parallel      
AA7 6 7 ? parallel      
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? parallel      
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? parallel      
AA9 5 6 ? parallel      
AA9 6 7 ? parallel      
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? parallel      
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB2 4 5 ? parallel      
AB2 5 6 ? parallel      
AB2 6 7 ? parallel      
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 TRP A 72  ? VAL A 74  ? TRP A 72  VAL A 74  
AA1 2 ARG A 5   ? ARG A 17  ? ARG A 5   ARG A 17  
AA1 3 ASP A 29  ? THR A 40  ? ASP A 29  THR A 40  
AA1 4 VAL A 46  ? ILE A 48  ? VAL A 46  ILE A 48  
AA1 5 TYR A 97  ? LEU A 99  ? TYR A 97  LEU A 99  
AA1 6 ILE A 118 ? ARG A 122 ? ILE A 118 ARG A 122 
AA1 7 LYS A 151 ? LEU A 155 ? LYS A 151 LEU A 155 
AA2 1 ILE A 170 ? PHE A 174 ? ILE A 170 PHE A 174 
AA2 2 SER A 183 ? LEU A 189 ? SER A 183 LEU A 189 
AA2 3 GLY A 193 ? VAL A 199 ? GLY A 193 VAL A 199 
AA2 4 LEU A 240 ? TYR A 243 ? LEU A 240 TYR A 243 
AA3 1 TRP B 72  ? VAL B 74  ? TRP B 72  VAL B 74  
AA3 2 ARG B 5   ? ARG B 17  ? ARG B 5   ARG B 17  
AA3 3 ASP B 29  ? THR B 40  ? ASP B 29  THR B 40  
AA3 4 ASN B 45  ? ILE B 48  ? ASN B 45  ILE B 48  
AA3 5 VAL B 95  ? LEU B 99  ? VAL B 95  LEU B 99  
AA3 6 ILE B 118 ? ARG B 122 ? ILE B 118 ARG B 122 
AA3 7 LYS B 151 ? LEU B 155 ? LYS B 151 LEU B 155 
AA4 1 ILE B 170 ? PHE B 174 ? ILE B 170 PHE B 174 
AA4 2 SER B 183 ? LEU B 189 ? SER B 183 LEU B 189 
AA4 3 GLY B 193 ? VAL B 199 ? GLY B 193 VAL B 199 
AA4 4 LEU B 240 ? TYR B 243 ? LEU B 240 TYR B 243 
AA5 1 TRP C 72  ? VAL C 74  ? TRP C 72  VAL C 74  
AA5 2 LEU C 6   ? ARG C 17  ? LEU C 6   ARG C 17  
AA5 3 ASP C 29  ? ILE C 39  ? ASP C 29  ILE C 39  
AA5 4 VAL C 46  ? ILE C 48  ? VAL C 46  ILE C 48  
AA5 5 TYR C 97  ? LEU C 99  ? TYR C 97  LEU C 99  
AA5 6 ILE C 118 ? ARG C 122 ? ILE C 118 ARG C 122 
AA5 7 LYS C 151 ? LEU C 155 ? LYS C 151 LEU C 155 
AA6 1 ILE C 170 ? PHE C 174 ? ILE C 170 PHE C 174 
AA6 2 SER C 183 ? LEU C 189 ? SER C 183 LEU C 189 
AA6 3 GLY C 193 ? VAL C 199 ? GLY C 193 VAL C 199 
AA6 4 LEU C 240 ? TYR C 243 ? LEU C 240 TYR C 243 
AA7 1 TRP D 72  ? VAL D 74  ? TRP D 72  VAL D 74  
AA7 2 ARG D 5   ? ARG D 17  ? ARG D 5   ARG D 17  
AA7 3 ASP D 29  ? THR D 40  ? ASP D 29  THR D 40  
AA7 4 ASN D 45  ? ILE D 48  ? ASN D 45  ILE D 48  
AA7 5 VAL D 95  ? LEU D 99  ? VAL D 95  LEU D 99  
AA7 6 ILE D 118 ? ARG D 122 ? ILE D 118 ARG D 122 
AA7 7 LYS D 151 ? LEU D 155 ? LYS D 151 LEU D 155 
AA8 1 ILE D 170 ? PHE D 174 ? ILE D 170 PHE D 174 
AA8 2 SER D 183 ? LEU D 189 ? SER D 183 LEU D 189 
AA8 3 GLY D 193 ? VAL D 199 ? GLY D 193 VAL D 199 
AA8 4 LEU D 240 ? TYR D 243 ? LEU D 240 TYR D 243 
AA9 1 TRP E 72  ? VAL E 74  ? TRP E 72  VAL E 74  
AA9 2 ARG E 5   ? ARG E 17  ? ARG E 5   ARG E 17  
AA9 3 ASP E 29  ? THR E 40  ? ASP E 29  THR E 40  
AA9 4 VAL E 46  ? ILE E 48  ? VAL E 46  ILE E 48  
AA9 5 TYR E 97  ? LEU E 99  ? TYR E 97  LEU E 99  
AA9 6 ILE E 118 ? ARG E 122 ? ILE E 118 ARG E 122 
AA9 7 LYS E 151 ? LEU E 155 ? LYS E 151 LEU E 155 
AB1 1 ILE E 170 ? PHE E 174 ? ILE E 170 PHE E 174 
AB1 2 SER E 183 ? LEU E 189 ? SER E 183 LEU E 189 
AB1 3 GLY E 193 ? VAL E 199 ? GLY E 193 VAL E 199 
AB1 4 LEU E 240 ? TYR E 243 ? LEU E 240 TYR E 243 
AB2 1 TRP F 72  ? VAL F 74  ? TRP F 72  VAL F 74  
AB2 2 ARG F 5   ? ARG F 17  ? ARG F 5   ARG F 17  
AB2 3 ASP F 29  ? HIS F 41  ? ASP F 29  HIS F 41  
AB2 4 GLY F 44  ? ILE F 48  ? GLY F 44  ILE F 48  
AB2 5 TYR F 97  ? LEU F 99  ? TYR F 97  LEU F 99  
AB2 6 ILE F 118 ? ARG F 122 ? ILE F 118 ARG F 122 
AB2 7 LYS F 151 ? LEU F 155 ? LYS F 151 LEU F 155 
AB3 1 ILE F 170 ? PHE F 174 ? ILE F 170 PHE F 174 
AB3 2 SER F 183 ? LEU F 189 ? SER F 183 LEU F 189 
AB3 3 GLY F 193 ? VAL F 199 ? GLY F 193 VAL F 199 
AB3 4 LEU F 240 ? TYR F 243 ? LEU F 240 TYR F 243 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O VAL A 74  ? O VAL A 74  N THR A 13  ? N THR A 13  
AA1 2 3 N TYR A 7   ? N TYR A 7   O LEU A 38  ? O LEU A 38  
AA1 3 4 N ILE A 39  ? N ILE A 39  O VAL A 46  ? O VAL A 46  
AA1 4 5 N VAL A 47  ? N VAL A 47  O LEU A 99  ? O LEU A 99  
AA1 5 6 N VAL A 98  ? N VAL A 98  O ILE A 120 ? O ILE A 120 
AA1 6 7 N HIS A 119 ? N HIS A 119 O HIS A 153 ? O HIS A 153 
AA2 1 2 N ILE A 173 ? N ILE A 173 O SER A 184 ? O SER A 184 
AA2 2 3 N LEU A 187 ? N LEU A 187 O VAL A 195 ? O VAL A 195 
AA2 3 4 N LEU A 196 ? N LEU A 196 O LEU A 240 ? O LEU A 240 
AA3 1 2 O TRP B 72  ? O TRP B 72  N LYS B 15  ? N LYS B 15  
AA3 2 3 N PHE B 9   ? N PHE B 9   O TRP B 36  ? O TRP B 36  
AA3 3 4 N ILE B 39  ? N ILE B 39  O VAL B 46  ? O VAL B 46  
AA3 4 5 N VAL B 47  ? N VAL B 47  O LEU B 99  ? O LEU B 99  
AA3 5 6 N VAL B 98  ? N VAL B 98  O ILE B 120 ? O ILE B 120 
AA3 6 7 N HIS B 119 ? N HIS B 119 O LYS B 151 ? O LYS B 151 
AA4 1 2 N ILE B 173 ? N ILE B 173 O SER B 184 ? O SER B 184 
AA4 2 3 N LEU B 187 ? N LEU B 187 O VAL B 195 ? O VAL B 195 
AA4 3 4 N LEU B 196 ? N LEU B 196 O LEU B 240 ? O LEU B 240 
AA5 1 2 O VAL C 74  ? O VAL C 74  N THR C 13  ? N THR C 13  
AA5 2 3 N CYS C 16  ? N CYS C 16  O TYR C 30  ? O TYR C 30  
AA5 3 4 N ILE C 39  ? N ILE C 39  O VAL C 46  ? O VAL C 46  
AA5 4 5 N VAL C 47  ? N VAL C 47  O LEU C 99  ? O LEU C 99  
AA5 5 6 N VAL C 98  ? N VAL C 98  O ILE C 120 ? O ILE C 120 
AA5 6 7 N HIS C 119 ? N HIS C 119 O HIS C 153 ? O HIS C 153 
AA6 1 2 N ILE C 173 ? N ILE C 173 O SER C 184 ? O SER C 184 
AA6 2 3 N LEU C 187 ? N LEU C 187 O VAL C 195 ? O VAL C 195 
AA6 3 4 N LEU C 196 ? N LEU C 196 O LEU C 240 ? O LEU C 240 
AA7 1 2 O VAL D 74  ? O VAL D 74  N THR D 13  ? N THR D 13  
AA7 2 3 N CYS D 16  ? N CYS D 16  O TYR D 30  ? O TYR D 30  
AA7 3 4 N TYR D 37  ? N TYR D 37  O ILE D 48  ? O ILE D 48  
AA7 4 5 N VAL D 47  ? N VAL D 47  O LEU D 99  ? O LEU D 99  
AA7 5 6 N VAL D 98  ? N VAL D 98  O ILE D 120 ? O ILE D 120 
AA7 6 7 N HIS D 119 ? N HIS D 119 O LYS D 151 ? O LYS D 151 
AA8 1 2 N ILE D 173 ? N ILE D 173 O SER D 184 ? O SER D 184 
AA8 2 3 N LEU D 187 ? N LEU D 187 O VAL D 195 ? O VAL D 195 
AA8 3 4 N LEU D 196 ? N LEU D 196 O LEU D 240 ? O LEU D 240 
AA9 1 2 O VAL E 74  ? O VAL E 74  N THR E 13  ? N THR E 13  
AA9 2 3 N TYR E 7   ? N TYR E 7   O LEU E 38  ? O LEU E 38  
AA9 3 4 N ILE E 39  ? N ILE E 39  O VAL E 46  ? O VAL E 46  
AA9 4 5 N VAL E 47  ? N VAL E 47  O LEU E 99  ? O LEU E 99  
AA9 5 6 N VAL E 98  ? N VAL E 98  O ILE E 120 ? O ILE E 120 
AA9 6 7 N HIS E 119 ? N HIS E 119 O LYS E 151 ? O LYS E 151 
AB1 1 2 N ILE E 173 ? N ILE E 173 O SER E 184 ? O SER E 184 
AB1 2 3 N LEU E 187 ? N LEU E 187 O VAL E 195 ? O VAL E 195 
AB1 3 4 N LEU E 196 ? N LEU E 196 O LEU E 240 ? O LEU E 240 
AB2 1 2 O TRP F 72  ? O TRP F 72  N LYS F 15  ? N LYS F 15  
AB2 2 3 N CYS F 16  ? N CYS F 16  O TYR F 30  ? O TYR F 30  
AB2 3 4 N TYR F 37  ? N TYR F 37  O ILE F 48  ? O ILE F 48  
AB2 4 5 N VAL F 47  ? N VAL F 47  O LEU F 99  ? O LEU F 99  
AB2 5 6 N VAL F 98  ? N VAL F 98  O ILE F 120 ? O ILE F 120 
AB2 6 7 N HIS F 119 ? N HIS F 119 O LYS F 151 ? O LYS F 151 
AB3 1 2 N ILE F 173 ? N ILE F 173 O SER F 184 ? O SER F 184 
AB3 2 3 N LEU F 187 ? N LEU F 187 O VAL F 195 ? O VAL F 195 
AB3 3 4 N LEU F 196 ? N LEU F 196 O LEU F 240 ? O LEU F 240 
# 
_pdbx_entry_details.entry_id                   9KHO 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PHE A 9   ? ? -108.86 -169.23 
2  1 CYS A 16  ? ? -149.02 -153.41 
3  1 ASP A 49  ? ? 74.95   -57.83  
4  1 ASP A 94  ? ? -93.50  37.46   
5  1 ALA A 131 ? ? -140.37 58.00   
6  1 VAL A 199 ? ? 50.50   -133.55 
7  1 LEU A 217 ? ? -170.23 148.76  
8  1 HIS A 245 ? ? -152.66 51.30   
9  1 LEU B 27  ? ? -105.77 57.32   
10 1 ASP B 49  ? ? 72.18   -65.98  
11 1 ASP B 94  ? ? -90.88  30.40   
12 1 VAL B 199 ? ? 52.17   -132.51 
13 1 HIS B 245 ? ? -145.31 59.07   
14 1 THR C 11  ? ? -102.06 74.86   
15 1 ASP C 49  ? ? 73.60   -55.51  
16 1 ASP C 94  ? ? -97.26  41.12   
17 1 HIS C 102 ? ? -175.21 -178.76 
18 1 ASP C 146 ? ? -104.38 68.29   
19 1 ASP C 168 ? ? 59.56   9.63    
20 1 VAL C 199 ? ? 49.48   -132.84 
21 1 HIS C 245 ? ? -150.53 58.09   
22 1 THR D 11  ? ? -101.16 66.88   
23 1 CYS D 16  ? ? -152.65 -154.67 
24 1 ASP D 49  ? ? 70.04   -60.83  
25 1 VAL D 199 ? ? 47.50   -133.70 
26 1 HIS D 245 ? ? -147.67 56.34   
27 1 THR E 11  ? ? -92.04  51.44   
28 1 ASP E 49  ? ? 73.17   -62.48  
29 1 ASP E 94  ? ? -97.86  41.99   
30 1 VAL E 199 ? ? 45.96   -134.82 
31 1 PHE F 9   ? ? -101.05 -163.88 
32 1 GLN F 10  ? ? -172.05 132.21  
33 1 THR F 11  ? ? -108.23 71.19   
34 1 ASP F 49  ? ? 73.21   -63.03  
35 1 ASP F 94  ? ? -95.61  31.23   
36 1 VAL F 199 ? ? 44.14   -136.52 
37 1 HIS F 245 ? ? -151.04 58.34   
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? B HOH 582 ? 7.33 . 
2 1 O ? E HOH 571 ? 5.89 . 
3 1 O ? F HOH 543 ? 5.82 . 
4 1 O ? F HOH 544 ? 6.02 . 
5 1 O ? F HOH 545 ? 6.72 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A ALA 2   ? A ALA 2   
3  1 Y 1 A ALA 256 ? A ALA 256 
4  1 Y 1 A PRO 257 ? A PRO 257 
5  1 Y 1 A GLU 258 ? A GLU 258 
6  1 Y 1 A TYR 259 ? A TYR 259 
7  1 Y 1 A TYR 260 ? A TYR 260 
8  1 Y 1 A ALA 261 ? A ALA 261 
9  1 Y 1 B MET 1   ? B MET 1   
10 1 Y 1 B ALA 2   ? B ALA 2   
11 1 Y 1 B ALA 3   ? B ALA 3   
12 1 Y 1 B ALA 256 ? B ALA 256 
13 1 Y 1 B PRO 257 ? B PRO 257 
14 1 Y 1 B GLU 258 ? B GLU 258 
15 1 Y 1 B TYR 259 ? B TYR 259 
16 1 Y 1 B TYR 260 ? B TYR 260 
17 1 Y 1 B ALA 261 ? B ALA 261 
18 1 Y 1 C MET 1   ? C MET 1   
19 1 Y 1 C ALA 2   ? C ALA 2   
20 1 Y 1 C ALA 3   ? C ALA 3   
21 1 Y 1 C PRO 4   ? C PRO 4   
22 1 Y 1 C PRO 257 ? C PRO 257 
23 1 Y 1 C GLU 258 ? C GLU 258 
24 1 Y 1 C TYR 259 ? C TYR 259 
25 1 Y 1 C TYR 260 ? C TYR 260 
26 1 Y 1 C ALA 261 ? C ALA 261 
27 1 Y 1 D MET 1   ? D MET 1   
28 1 Y 1 D ALA 2   ? D ALA 2   
29 1 Y 1 D ALA 256 ? D ALA 256 
30 1 Y 1 D PRO 257 ? D PRO 257 
31 1 Y 1 D GLU 258 ? D GLU 258 
32 1 Y 1 D TYR 259 ? D TYR 259 
33 1 Y 1 D TYR 260 ? D TYR 260 
34 1 Y 1 D ALA 261 ? D ALA 261 
35 1 Y 1 E MET 1   ? E MET 1   
36 1 Y 1 E ALA 2   ? E ALA 2   
37 1 Y 1 E ALA 3   ? E ALA 3   
38 1 Y 1 E ALA 256 ? E ALA 256 
39 1 Y 1 E PRO 257 ? E PRO 257 
40 1 Y 1 E GLU 258 ? E GLU 258 
41 1 Y 1 E TYR 259 ? E TYR 259 
42 1 Y 1 E TYR 260 ? E TYR 260 
43 1 Y 1 E ALA 261 ? E ALA 261 
44 1 Y 1 F MET 1   ? F MET 1   
45 1 Y 1 F ALA 2   ? F ALA 2   
46 1 Y 1 F LEU 255 ? F LEU 255 
47 1 Y 1 F ALA 256 ? F ALA 256 
48 1 Y 1 F PRO 257 ? F PRO 257 
49 1 Y 1 F GLU 258 ? F GLU 258 
50 1 Y 1 F TYR 259 ? F TYR 259 
51 1 Y 1 F TYR 260 ? F TYR 260 
52 1 Y 1 F ALA 261 ? F ALA 261 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HIS N    N  N N 137 
HIS CA   C  N S 138 
HIS C    C  N N 139 
HIS O    O  N N 140 
HIS CB   C  N N 141 
HIS CG   C  Y N 142 
HIS ND1  N  Y N 143 
HIS CD2  C  Y N 144 
HIS CE1  C  Y N 145 
HIS NE2  N  Y N 146 
HIS OXT  O  N N 147 
HIS H    H  N N 148 
HIS H2   H  N N 149 
HIS HA   H  N N 150 
HIS HB2  H  N N 151 
HIS HB3  H  N N 152 
HIS HD1  H  N N 153 
HIS HD2  H  N N 154 
HIS HE1  H  N N 155 
HIS HE2  H  N N 156 
HIS HXT  H  N N 157 
HOH O    O  N N 158 
HOH H1   H  N N 159 
HOH H2   H  N N 160 
ILE N    N  N N 161 
ILE CA   C  N S 162 
ILE C    C  N N 163 
ILE O    O  N N 164 
ILE CB   C  N S 165 
ILE CG1  C  N N 166 
ILE CG2  C  N N 167 
ILE CD1  C  N N 168 
ILE OXT  O  N N 169 
ILE H    H  N N 170 
ILE H2   H  N N 171 
ILE HA   H  N N 172 
ILE HB   H  N N 173 
ILE HG12 H  N N 174 
ILE HG13 H  N N 175 
ILE HG21 H  N N 176 
ILE HG22 H  N N 177 
ILE HG23 H  N N 178 
ILE HD11 H  N N 179 
ILE HD12 H  N N 180 
ILE HD13 H  N N 181 
ILE HXT  H  N N 182 
LEU N    N  N N 183 
LEU CA   C  N S 184 
LEU C    C  N N 185 
LEU O    O  N N 186 
LEU CB   C  N N 187 
LEU CG   C  N N 188 
LEU CD1  C  N N 189 
LEU CD2  C  N N 190 
LEU OXT  O  N N 191 
LEU H    H  N N 192 
LEU H2   H  N N 193 
LEU HA   H  N N 194 
LEU HB2  H  N N 195 
LEU HB3  H  N N 196 
LEU HG   H  N N 197 
LEU HD11 H  N N 198 
LEU HD12 H  N N 199 
LEU HD13 H  N N 200 
LEU HD21 H  N N 201 
LEU HD22 H  N N 202 
LEU HD23 H  N N 203 
LEU HXT  H  N N 204 
LYS N    N  N N 205 
LYS CA   C  N S 206 
LYS C    C  N N 207 
LYS O    O  N N 208 
LYS CB   C  N N 209 
LYS CG   C  N N 210 
LYS CD   C  N N 211 
LYS CE   C  N N 212 
LYS NZ   N  N N 213 
LYS OXT  O  N N 214 
LYS H    H  N N 215 
LYS H2   H  N N 216 
LYS HA   H  N N 217 
LYS HB2  H  N N 218 
LYS HB3  H  N N 219 
LYS HG2  H  N N 220 
LYS HG3  H  N N 221 
LYS HD2  H  N N 222 
LYS HD3  H  N N 223 
LYS HE2  H  N N 224 
LYS HE3  H  N N 225 
LYS HZ1  H  N N 226 
LYS HZ2  H  N N 227 
LYS HZ3  H  N N 228 
LYS HXT  H  N N 229 
MET N    N  N N 230 
MET CA   C  N S 231 
MET C    C  N N 232 
MET O    O  N N 233 
MET CB   C  N N 234 
MET CG   C  N N 235 
MET SD   S  N N 236 
MET CE   C  N N 237 
MET OXT  O  N N 238 
MET H    H  N N 239 
MET H2   H  N N 240 
MET HA   H  N N 241 
MET HB2  H  N N 242 
MET HB3  H  N N 243 
MET HG2  H  N N 244 
MET HG3  H  N N 245 
MET HE1  H  N N 246 
MET HE2  H  N N 247 
MET HE3  H  N N 248 
MET HXT  H  N N 249 
NI  NI   NI N N 250 
PHE N    N  N N 251 
PHE CA   C  N S 252 
PHE C    C  N N 253 
PHE O    O  N N 254 
PHE CB   C  N N 255 
PHE CG   C  Y N 256 
PHE CD1  C  Y N 257 
PHE CD2  C  Y N 258 
PHE CE1  C  Y N 259 
PHE CE2  C  Y N 260 
PHE CZ   C  Y N 261 
PHE OXT  O  N N 262 
PHE H    H  N N 263 
PHE H2   H  N N 264 
PHE HA   H  N N 265 
PHE HB2  H  N N 266 
PHE HB3  H  N N 267 
PHE HD1  H  N N 268 
PHE HD2  H  N N 269 
PHE HE1  H  N N 270 
PHE HE2  H  N N 271 
PHE HZ   H  N N 272 
PHE HXT  H  N N 273 
PRO N    N  N N 274 
PRO CA   C  N S 275 
PRO C    C  N N 276 
PRO O    O  N N 277 
PRO CB   C  N N 278 
PRO CG   C  N N 279 
PRO CD   C  N N 280 
PRO OXT  O  N N 281 
PRO H    H  N N 282 
PRO HA   H  N N 283 
PRO HB2  H  N N 284 
PRO HB3  H  N N 285 
PRO HG2  H  N N 286 
PRO HG3  H  N N 287 
PRO HD2  H  N N 288 
PRO HD3  H  N N 289 
PRO HXT  H  N N 290 
SER N    N  N N 291 
SER CA   C  N S 292 
SER C    C  N N 293 
SER O    O  N N 294 
SER CB   C  N N 295 
SER OG   O  N N 296 
SER OXT  O  N N 297 
SER H    H  N N 298 
SER H2   H  N N 299 
SER HA   H  N N 300 
SER HB2  H  N N 301 
SER HB3  H  N N 302 
SER HG   H  N N 303 
SER HXT  H  N N 304 
THR N    N  N N 305 
THR CA   C  N S 306 
THR C    C  N N 307 
THR O    O  N N 308 
THR CB   C  N R 309 
THR OG1  O  N N 310 
THR CG2  C  N N 311 
THR OXT  O  N N 312 
THR H    H  N N 313 
THR H2   H  N N 314 
THR HA   H  N N 315 
THR HB   H  N N 316 
THR HG1  H  N N 317 
THR HG21 H  N N 318 
THR HG22 H  N N 319 
THR HG23 H  N N 320 
THR HXT  H  N N 321 
TRP N    N  N N 322 
TRP CA   C  N S 323 
TRP C    C  N N 324 
TRP O    O  N N 325 
TRP CB   C  N N 326 
TRP CG   C  Y N 327 
TRP CD1  C  Y N 328 
TRP CD2  C  Y N 329 
TRP NE1  N  Y N 330 
TRP CE2  C  Y N 331 
TRP CE3  C  Y N 332 
TRP CZ2  C  Y N 333 
TRP CZ3  C  Y N 334 
TRP CH2  C  Y N 335 
TRP OXT  O  N N 336 
TRP H    H  N N 337 
TRP H2   H  N N 338 
TRP HA   H  N N 339 
TRP HB2  H  N N 340 
TRP HB3  H  N N 341 
TRP HD1  H  N N 342 
TRP HE1  H  N N 343 
TRP HE3  H  N N 344 
TRP HZ2  H  N N 345 
TRP HZ3  H  N N 346 
TRP HH2  H  N N 347 
TRP HXT  H  N N 348 
TYR N    N  N N 349 
TYR CA   C  N S 350 
TYR C    C  N N 351 
TYR O    O  N N 352 
TYR CB   C  N N 353 
TYR CG   C  Y N 354 
TYR CD1  C  Y N 355 
TYR CD2  C  Y N 356 
TYR CE1  C  Y N 357 
TYR CE2  C  Y N 358 
TYR CZ   C  Y N 359 
TYR OH   O  N N 360 
TYR OXT  O  N N 361 
TYR H    H  N N 362 
TYR H2   H  N N 363 
TYR HA   H  N N 364 
TYR HB2  H  N N 365 
TYR HB3  H  N N 366 
TYR HD1  H  N N 367 
TYR HD2  H  N N 368 
TYR HE1  H  N N 369 
TYR HE2  H  N N 370 
TYR HH   H  N N 371 
TYR HXT  H  N N 372 
VAL N    N  N N 373 
VAL CA   C  N S 374 
VAL C    C  N N 375 
VAL O    O  N N 376 
VAL CB   C  N N 377 
VAL CG1  C  N N 378 
VAL CG2  C  N N 379 
VAL OXT  O  N N 380 
VAL H    H  N N 381 
VAL H2   H  N N 382 
VAL HA   H  N N 383 
VAL HB   H  N N 384 
VAL HG11 H  N N 385 
VAL HG12 H  N N 386 
VAL HG13 H  N N 387 
VAL HG21 H  N N 388 
VAL HG22 H  N N 389 
VAL HG23 H  N N 390 
VAL HXT  H  N N 391 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
# 
_pdbx_audit_support.funding_organization   'Other government' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           GZC20232364 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9KHO 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.012804 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.004597 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.006674 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.013251 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
N  
NI 
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N   . ALA A 1 3   ? 40.142  62.536  39.662  1.00 33.43  ? 3   ALA A N   1 
ATOM   2     C  CA  . ALA A 1 3   ? 40.249  64.004  39.727  1.00 40.94  ? 3   ALA A CA  1 
ATOM   3     C  C   . ALA A 1 3   ? 40.132  64.535  41.167  1.00 37.93  ? 3   ALA A C   1 
ATOM   4     O  O   . ALA A 1 3   ? 39.395  63.968  41.972  1.00 41.28  ? 3   ALA A O   1 
ATOM   5     C  CB  . ALA A 1 3   ? 39.196  64.647  38.843  1.00 41.39  ? 3   ALA A CB  1 
ATOM   6     N  N   . PRO A 1 4   ? 40.837  65.626  41.479  1.00 38.20  ? 4   PRO A N   1 
ATOM   7     C  CA  . PRO A 1 4   ? 41.003  66.027  42.888  1.00 37.03  ? 4   PRO A CA  1 
ATOM   8     C  C   . PRO A 1 4   ? 39.704  66.444  43.559  1.00 35.30  ? 4   PRO A C   1 
ATOM   9     O  O   . PRO A 1 4   ? 38.796  66.990  42.931  1.00 40.60  ? 4   PRO A O   1 
ATOM   10    C  CB  . PRO A 1 4   ? 41.972  67.215  42.806  1.00 36.16  ? 4   PRO A CB  1 
ATOM   11    C  CG  . PRO A 1 4   ? 42.679  67.031  41.509  1.00 40.28  ? 4   PRO A CG  1 
ATOM   12    C  CD  . PRO A 1 4   ? 41.626  66.484  40.580  1.00 37.69  ? 4   PRO A CD  1 
ATOM   13    N  N   . ARG A 1 5   ? 39.636  66.202  44.868  1.00 32.68  ? 5   ARG A N   1 
ATOM   14    C  CA  . ARG A 1 5   ? 38.468  66.543  45.673  1.00 35.52  ? 5   ARG A CA  1 
ATOM   15    C  C   . ARG A 1 5   ? 38.901  67.047  47.041  1.00 34.95  ? 5   ARG A C   1 
ATOM   16    O  O   . ARG A 1 5   ? 39.968  66.684  47.544  1.00 31.72  ? 5   ARG A O   1 
ATOM   17    C  CB  . ARG A 1 5   ? 37.538  65.350  45.894  1.00 36.63  ? 5   ARG A CB  1 
ATOM   18    C  CG  . ARG A 1 5   ? 36.839  64.857  44.659  1.00 39.26  ? 5   ARG A CG  1 
ATOM   19    C  CD  . ARG A 1 5   ? 36.326  63.463  44.915  1.00 42.03  ? 5   ARG A CD  1 
ATOM   20    N  NE  . ARG A 1 5   ? 35.128  63.169  44.146  1.00 48.78  ? 5   ARG A NE  1 
ATOM   21    C  CZ  . ARG A 1 5   ? 34.484  62.012  44.203  1.00 52.21  ? 5   ARG A CZ  1 
ATOM   22    N  NH1 . ARG A 1 5   ? 34.927  61.015  44.954  1.00 41.70  ? 5   ARG A NH1 1 
ATOM   23    N  NH2 . ARG A 1 5   ? 33.365  61.856  43.496  1.00 42.89  ? 5   ARG A NH2 1 
ATOM   24    N  N   . LEU A 1 6   ? 38.034  67.853  47.649  1.00 30.03  ? 6   LEU A N   1 
ATOM   25    C  CA  . LEU A 1 6   ? 38.242  68.400  48.978  1.00 30.22  ? 6   LEU A CA  1 
ATOM   26    C  C   . LEU A 1 6   ? 37.163  67.859  49.904  1.00 31.20  ? 6   LEU A C   1 
ATOM   27    O  O   . LEU A 1 6   ? 35.976  67.966  49.593  1.00 32.34  ? 6   LEU A O   1 
ATOM   28    C  CB  . LEU A 1 6   ? 38.191  69.937  48.957  1.00 26.81  ? 6   LEU A CB  1 
ATOM   29    C  CG  . LEU A 1 6   ? 37.966  70.641  50.294  1.00 26.43  ? 6   LEU A CG  1 
ATOM   30    C  CD1 . LEU A 1 6   ? 39.124  70.350  51.221  1.00 25.96  ? 6   LEU A CD1 1 
ATOM   31    C  CD2 . LEU A 1 6   ? 37.758  72.177  50.106  1.00 27.90  ? 6   LEU A CD2 1 
ATOM   32    N  N   . TYR A 1 7   ? 37.574  67.297  51.042  1.00 32.00  ? 7   TYR A N   1 
ATOM   33    C  CA  . TYR A 1 7   ? 36.656  66.834  52.075  1.00 30.02  ? 7   TYR A CA  1 
ATOM   34    C  C   . TYR A 1 7   ? 36.932  67.616  53.351  1.00 30.61  ? 7   TYR A C   1 
ATOM   35    O  O   . TYR A 1 7   ? 38.086  67.719  53.786  1.00 30.80  ? 7   TYR A O   1 
ATOM   36    C  CB  . TYR A 1 7   ? 36.806  65.322  52.347  1.00 28.26  ? 7   TYR A CB  1 
ATOM   37    C  CG  . TYR A 1 7   ? 36.445  64.416  51.178  1.00 32.49  ? 7   TYR A CG  1 
ATOM   38    C  CD1 . TYR A 1 7   ? 37.357  64.153  50.174  1.00 28.20  ? 7   TYR A CD1 1 
ATOM   39    C  CD2 . TYR A 1 7   ? 35.194  63.809  51.098  1.00 32.36  ? 7   TYR A CD2 1 
ATOM   40    C  CE1 . TYR A 1 7   ? 37.040  63.325  49.111  1.00 35.27  ? 7   TYR A CE1 1 
ATOM   41    C  CE2 . TYR A 1 7   ? 34.868  62.977  50.045  1.00 33.27  ? 7   TYR A CE2 1 
ATOM   42    C  CZ  . TYR A 1 7   ? 35.794  62.744  49.050  1.00 41.20  ? 7   TYR A CZ  1 
ATOM   43    O  OH  . TYR A 1 7   ? 35.478  61.926  47.992  1.00 46.00  ? 7   TYR A OH  1 
ATOM   44    N  N   . MET A 1 8   ? 35.885  68.153  53.960  1.00 28.02  ? 8   MET A N   1 
ATOM   45    C  CA  . MET A 1 8   ? 36.035  68.923  55.187  1.00 35.30  ? 8   MET A CA  1 
ATOM   46    C  C   . MET A 1 8   ? 35.551  68.083  56.360  1.00 32.92  ? 8   MET A C   1 
ATOM   47    O  O   . MET A 1 8   ? 34.391  67.659  56.388  1.00 37.27  ? 8   MET A O   1 
ATOM   48    C  CB  . MET A 1 8   ? 35.282  70.251  55.092  1.00 35.30  ? 8   MET A CB  1 
ATOM   49    C  CG  . MET A 1 8   ? 35.619  70.993  53.793  1.00 34.25  ? 8   MET A CG  1 
ATOM   50    S  SD  . MET A 1 8   ? 35.596  72.792  53.948  1.00 42.76  ? 8   MET A SD  1 
ATOM   51    C  CE  . MET A 1 8   ? 34.042  72.997  54.780  1.00 37.81  ? 8   MET A CE  1 
ATOM   52    N  N   . PHE A 1 9   ? 36.449  67.817  57.297  1.00 27.36  ? 9   PHE A N   1 
ATOM   53    C  CA  . PHE A 1 9   ? 36.162  67.094  58.519  1.00 29.85  ? 9   PHE A CA  1 
ATOM   54    C  C   . PHE A 1 9   ? 36.195  68.029  59.721  1.00 34.21  ? 9   PHE A C   1 
ATOM   55    O  O   . PHE A 1 9   ? 36.329  69.255  59.596  1.00 34.85  ? 9   PHE A O   1 
ATOM   56    C  CB  . PHE A 1 9   ? 37.164  65.978  58.748  1.00 29.87  ? 9   PHE A CB  1 
ATOM   57    C  CG  . PHE A 1 9   ? 37.026  64.824  57.829  1.00 34.00  ? 9   PHE A CG  1 
ATOM   58    C  CD1 . PHE A 1 9   ? 37.697  64.808  56.620  1.00 26.36  ? 9   PHE A CD1 1 
ATOM   59    C  CD2 . PHE A 1 9   ? 36.268  63.717  58.196  1.00 32.62  ? 9   PHE A CD2 1 
ATOM   60    C  CE1 . PHE A 1 9   ? 37.599  63.719  55.782  1.00 34.42  ? 9   PHE A CE1 1 
ATOM   61    C  CE2 . PHE A 1 9   ? 36.161  62.616  57.355  1.00 31.44  ? 9   PHE A CE2 1 
ATOM   62    C  CZ  . PHE A 1 9   ? 36.823  62.614  56.151  1.00 35.65  ? 9   PHE A CZ  1 
ATOM   63    N  N   . GLN A 1 10  ? 36.166  67.418  60.901  1.00 31.58  ? 10  GLN A N   1 
ATOM   64    C  CA  . GLN A 1 10  ? 36.066  68.122  62.170  1.00 35.37  ? 10  GLN A CA  1 
ATOM   65    C  C   . GLN A 1 10  ? 36.426  67.169  63.313  1.00 36.38  ? 10  GLN A C   1 
ATOM   66    O  O   . GLN A 1 10  ? 35.815  66.102  63.433  1.00 37.15  ? 10  GLN A O   1 
ATOM   67    C  CB  . GLN A 1 10  ? 34.644  68.668  62.300  1.00 33.15  ? 10  GLN A CB  1 
ATOM   68    C  CG  . GLN A 1 10  ? 34.118  68.865  63.694  1.00 39.02  ? 10  GLN A CG  1 
ATOM   69    C  CD  . GLN A 1 10  ? 32.781  69.574  63.679  1.00 36.93  ? 10  GLN A CD  1 
ATOM   70    O  OE1 . GLN A 1 10  ? 32.057  69.542  62.677  1.00 35.46  ? 10  GLN A OE1 1 
ATOM   71    N  NE2 . GLN A 1 10  ? 32.457  70.240  64.777  1.00 33.92  ? 10  GLN A NE2 1 
ATOM   72    N  N   . THR A 1 11  ? 37.435  67.491  64.130  1.00 32.95  ? 11  THR A N   1 
ATOM   73    C  CA  . THR A 1 11  ? 37.669  66.714  65.357  1.00 33.08  ? 11  THR A CA  1 
ATOM   74    C  C   . THR A 1 11  ? 36.851  67.339  66.485  1.00 31.98  ? 11  THR A C   1 
ATOM   75    O  O   . THR A 1 11  ? 37.375  67.950  67.418  1.00 36.41  ? 11  THR A O   1 
ATOM   76    C  CB  . THR A 1 11  ? 39.158  66.641  65.722  1.00 31.42  ? 11  THR A CB  1 
ATOM   77    O  OG1 . THR A 1 11  ? 39.711  67.952  65.878  1.00 29.73  ? 11  THR A OG1 1 
ATOM   78    C  CG2 . THR A 1 11  ? 39.961  65.886  64.682  1.00 26.64  ? 11  THR A CG2 1 
ATOM   79    N  N   . GLY A 1 12  ? 35.530  67.214  66.354  1.00 33.60  ? 12  GLY A N   1 
ATOM   80    C  CA  . GLY A 1 12  ? 34.634  67.706  67.395  1.00 32.30  ? 12  GLY A CA  1 
ATOM   81    C  C   . GLY A 1 12  ? 34.655  69.218  67.535  1.00 32.63  ? 12  GLY A C   1 
ATOM   82    O  O   . GLY A 1 12  ? 34.622  69.971  66.552  1.00 32.73  ? 12  GLY A O   1 
ATOM   83    N  N   . THR A 1 13  ? 34.686  69.675  68.781  1.00 33.40  ? 13  THR A N   1 
ATOM   84    C  CA  . THR A 1 13  ? 34.627  71.096  69.082  1.00 36.03  ? 13  THR A CA  1 
ATOM   85    C  C   . THR A 1 13  ? 35.545  71.402  70.248  1.00 34.59  ? 13  THR A C   1 
ATOM   86    O  O   . THR A 1 13  ? 35.958  70.512  70.995  1.00 32.53  ? 13  THR A O   1 
ATOM   87    C  CB  . THR A 1 13  ? 33.215  71.589  69.474  1.00 37.73  ? 13  THR A CB  1 
ATOM   88    O  OG1 . THR A 1 13  ? 32.760  70.884  70.647  1.00 37.18  ? 13  THR A OG1 1 
ATOM   89    C  CG2 . THR A 1 13  ? 32.213  71.430  68.325  1.00 39.52  ? 13  THR A CG2 1 
ATOM   90    N  N   . LEU A 1 14  ? 35.824  72.692  70.403  1.00 32.72  ? 14  LEU A N   1 
ATOM   91    C  CA  . LEU A 1 14  ? 36.505  73.235  71.565  1.00 36.06  ? 14  LEU A CA  1 
ATOM   92    C  C   . LEU A 1 14  ? 35.529  74.109  72.341  1.00 39.34  ? 14  LEU A C   1 
ATOM   93    O  O   . LEU A 1 14  ? 34.755  74.869  71.750  1.00 37.45  ? 14  LEU A O   1 
ATOM   94    C  CB  . LEU A 1 14  ? 37.722  74.067  71.157  1.00 36.94  ? 14  LEU A CB  1 
ATOM   95    C  CG  . LEU A 1 14  ? 38.863  73.370  70.420  1.00 38.60  ? 14  LEU A CG  1 
ATOM   96    C  CD1 . LEU A 1 14  ? 39.951  74.389  70.049  1.00 30.87  ? 14  LEU A CD1 1 
ATOM   97    C  CD2 . LEU A 1 14  ? 39.435  72.198  71.236  1.00 34.78  ? 14  LEU A CD2 1 
ATOM   98    N  N   . LYS A 1 15  ? 35.561  73.990  73.662  1.00 37.75  ? 15  LYS A N   1 
ATOM   99    C  CA  . LYS A 1 15  ? 34.762  74.827  74.541  1.00 38.94  ? 15  LYS A CA  1 
ATOM   100   C  C   . LYS A 1 15  ? 35.684  75.871  75.149  1.00 39.23  ? 15  LYS A C   1 
ATOM   101   O  O   . LYS A 1 15  ? 36.680  75.525  75.789  1.00 39.77  ? 15  LYS A O   1 
ATOM   102   C  CB  . LYS A 1 15  ? 34.085  73.989  75.627  1.00 43.40  ? 15  LYS A CB  1 
ATOM   103   C  CG  . LYS A 1 15  ? 32.769  73.329  75.181  1.00 43.93  ? 15  LYS A CG  1 
ATOM   104   C  CD  . LYS A 1 15  ? 31.992  72.789  76.374  1.00 49.74  ? 15  LYS A CD  1 
ATOM   105   C  CE  . LYS A 1 15  ? 30.599  72.314  75.984  1.00 57.50  ? 15  LYS A CE  1 
ATOM   106   N  NZ  . LYS A 1 15  ? 29.597  73.426  76.018  1.00 63.07  ? 15  LYS A NZ  1 
ATOM   107   N  N   . CYS A 1 16  ? 35.363  77.143  74.935  1.00 37.12  ? 16  CYS A N   1 
ATOM   108   C  CA  . CYS A 1 16  ? 36.205  78.211  75.454  1.00 42.80  ? 16  CYS A CA  1 
ATOM   109   C  C   . CYS A 1 16  ? 35.358  79.425  75.776  1.00 46.38  ? 16  CYS A C   1 
ATOM   110   O  O   . CYS A 1 16  ? 34.165  79.297  76.058  1.00 48.05  ? 16  CYS A O   1 
ATOM   111   C  CB  . CYS A 1 16  ? 37.315  78.579  74.455  1.00 45.16  ? 16  CYS A CB  1 
ATOM   112   S  SG  . CYS A 1 16  ? 36.777  79.051  72.774  1.00 46.51  ? 16  CYS A SG  1 
ATOM   113   N  N   . ARG A 1 17  ? 35.953  80.606  75.733  1.00 48.61  ? 17  ARG A N   1 
ATOM   114   C  CA  . ARG A 1 17  ? 35.204  81.838  75.899  1.00 48.62  ? 17  ARG A CA  1 
ATOM   115   C  C   . ARG A 1 17  ? 35.221  82.629  74.599  1.00 51.12  ? 17  ARG A C   1 
ATOM   116   O  O   . ARG A 1 17  ? 36.062  82.406  73.716  1.00 49.65  ? 17  ARG A O   1 
ATOM   117   C  CB  . ARG A 1 17  ? 35.761  82.690  77.044  1.00 50.05  ? 17  ARG A CB  1 
ATOM   118   C  CG  . ARG A 1 17  ? 35.248  82.286  78.418  1.00 50.94  ? 17  ARG A CG  1 
ATOM   119   C  CD  . ARG A 1 17  ? 36.030  83.016  79.495  1.00 56.45  ? 17  ARG A CD  1 
ATOM   120   N  NE  . ARG A 1 17  ? 36.435  82.149  80.593  1.00 60.33  ? 17  ARG A NE  1 
ATOM   121   C  CZ  . ARG A 1 17  ? 35.720  81.948  81.692  1.00 64.90  ? 17  ARG A CZ  1 
ATOM   122   N  NH1 . ARG A 1 17  ? 34.545  82.533  81.869  1.00 60.36  ? 17  ARG A NH1 1 
ATOM   123   N  NH2 . ARG A 1 17  ? 36.201  81.150  82.642  1.00 68.24  ? 17  ARG A NH2 1 
ATOM   124   N  N   . VAL A 1 18  ? 34.254  83.547  74.489  1.00 48.49  ? 18  VAL A N   1 
ATOM   125   C  CA  . VAL A 1 18  ? 34.144  84.394  73.304  1.00 48.31  ? 18  VAL A CA  1 
ATOM   126   C  C   . VAL A 1 18  ? 35.410  85.225  73.134  1.00 45.37  ? 18  VAL A C   1 
ATOM   127   O  O   . VAL A 1 18  ? 35.868  85.464  72.010  1.00 44.38  ? 18  VAL A O   1 
ATOM   128   C  CB  . VAL A 1 18  ? 32.887  85.282  73.398  1.00 48.82  ? 18  VAL A CB  1 
ATOM   129   C  CG1 . VAL A 1 18  ? 32.790  86.210  72.204  1.00 46.95  ? 18  VAL A CG1 1 
ATOM   130   C  CG2 . VAL A 1 18  ? 31.649  84.427  73.508  1.00 49.17  ? 18  VAL A CG2 1 
ATOM   131   N  N   . CYS A 1 19  ? 36.013  85.649  74.250  1.00 43.92  ? 19  CYS A N   1 
ATOM   132   C  CA  . CYS A 1 19  ? 37.209  86.484  74.181  1.00 45.51  ? 19  CYS A CA  1 
ATOM   133   C  C   . CYS A 1 19  ? 38.390  85.735  73.573  1.00 41.74  ? 19  CYS A C   1 
ATOM   134   O  O   . CYS A 1 19  ? 39.235  86.356  72.929  1.00 43.11  ? 19  CYS A O   1 
ATOM   135   C  CB  . CYS A 1 19  ? 37.571  87.020  75.570  1.00 43.73  ? 19  CYS A CB  1 
ATOM   136   S  SG  . CYS A 1 19  ? 37.911  85.746  76.816  1.00 46.76  ? 19  CYS A SG  1 
ATOM   137   N  N   . ASN A 1 20  ? 38.468  84.412  73.748  1.00 44.14  ? 20  ASN A N   1 
ATOM   138   C  CA  . ASN A 1 20  ? 39.561  83.669  73.120  1.00 48.32  ? 20  ASN A CA  1 
ATOM   139   C  C   . ASN A 1 20  ? 39.456  83.676  71.596  1.00 45.63  ? 20  ASN A C   1 
ATOM   140   O  O   . ASN A 1 20  ? 40.470  83.483  70.916  1.00 39.45  ? 20  ASN A O   1 
ATOM   141   C  CB  . ASN A 1 20  ? 39.597  82.225  73.630  1.00 46.79  ? 20  ASN A CB  1 
ATOM   142   C  CG  . ASN A 1 20  ? 39.637  82.140  75.152  1.00 48.98  ? 20  ASN A CG  1 
ATOM   143   O  OD1 . ASN A 1 20  ? 38.797  81.480  75.771  1.00 44.11  ? 20  ASN A OD1 1 
ATOM   144   N  ND2 . ASN A 1 20  ? 40.606  82.816  75.758  1.00 46.82  ? 20  ASN A ND2 1 
ATOM   145   N  N   . ILE A 1 21  ? 38.257  83.888  71.060  1.00 40.04  ? 21  ILE A N   1 
ATOM   146   C  CA  . ILE A 1 21  ? 38.029  83.967  69.628  1.00 40.38  ? 21  ILE A CA  1 
ATOM   147   C  C   . ILE A 1 21  ? 37.981  85.413  69.151  1.00 41.25  ? 21  ILE A C   1 
ATOM   148   O  O   . ILE A 1 21  ? 38.614  85.763  68.156  1.00 42.42  ? 21  ILE A O   1 
ATOM   149   C  CB  . ILE A 1 21  ? 36.727  83.219  69.260  1.00 42.44  ? 21  ILE A CB  1 
ATOM   150   C  CG1 . ILE A 1 21  ? 36.773  81.768  69.753  1.00 39.52  ? 21  ILE A CG1 1 
ATOM   151   C  CG2 . ILE A 1 21  ? 36.450  83.307  67.747  1.00 38.20  ? 21  ILE A CG2 1 
ATOM   152   C  CD1 . ILE A 1 21  ? 38.003  80.975  69.310  1.00 39.37  ? 21  ILE A CD1 1 
ATOM   153   N  N   . LYS A 1 22  ? 37.245  86.259  69.863  1.00 41.57  ? 22  LYS A N   1 
ATOM   154   C  CA  . LYS A 1 22  ? 37.065  87.666  69.534  1.00 45.93  ? 22  LYS A CA  1 
ATOM   155   C  C   . LYS A 1 22  ? 37.639  88.477  70.694  1.00 46.70  ? 22  LYS A C   1 
ATOM   156   O  O   . LYS A 1 22  ? 37.068  88.488  71.793  1.00 41.48  ? 22  LYS A O   1 
ATOM   157   C  CB  . LYS A 1 22  ? 35.584  87.960  69.292  1.00 48.34  ? 22  LYS A CB  1 
ATOM   158   C  CG  . LYS A 1 22  ? 34.884  86.853  68.482  1.00 48.51  ? 22  LYS A CG  1 
ATOM   159   C  CD  . LYS A 1 22  ? 33.920  87.400  67.439  1.00 46.78  ? 22  LYS A CD  1 
ATOM   160   C  CE  . LYS A 1 22  ? 32.690  86.510  67.312  1.00 45.62  ? 22  LYS A CE  1 
ATOM   161   N  NZ  . LYS A 1 22  ? 32.126  86.476  65.921  1.00 40.68  ? 22  LYS A NZ  1 
ATOM   162   N  N   . MET A 1 23  ? 38.776  89.134  70.455  1.00 43.81  ? 23  MET A N   1 
ATOM   163   C  CA  . MET A 1 23  ? 39.577  89.688  71.545  1.00 43.43  ? 23  MET A CA  1 
ATOM   164   C  C   . MET A 1 23  ? 38.792  90.756  72.302  1.00 43.19  ? 23  MET A C   1 
ATOM   165   O  O   . MET A 1 23  ? 38.210  91.664  71.697  1.00 40.84  ? 23  MET A O   1 
ATOM   166   C  CB  . MET A 1 23  ? 40.887  90.283  71.003  1.00 38.90  ? 23  MET A CB  1 
ATOM   167   C  CG  . MET A 1 23  ? 41.825  90.799  72.090  1.00 37.99  ? 23  MET A CG  1 
ATOM   168   S  SD  . MET A 1 23  ? 43.033  92.030  71.539  1.00 43.88  ? 23  MET A SD  1 
ATOM   169   C  CE  . MET A 1 23  ? 44.264  90.997  70.745  1.00 38.26  ? 23  MET A CE  1 
ATOM   170   N  N   . ASN A 1 24  ? 38.777  90.628  73.636  1.00 42.67  ? 24  ASN A N   1 
ATOM   171   C  CA  . ASN A 1 24  ? 38.112  91.566  74.545  1.00 44.85  ? 24  ASN A CA  1 
ATOM   172   C  C   . ASN A 1 24  ? 36.609  91.672  74.285  1.00 48.89  ? 24  ASN A C   1 
ATOM   173   O  O   . ASN A 1 24  ? 35.983  92.680  74.627  1.00 47.03  ? 24  ASN A O   1 
ATOM   174   C  CB  . ASN A 1 24  ? 38.768  92.949  74.488  1.00 45.85  ? 24  ASN A CB  1 
ATOM   175   C  CG  . ASN A 1 24  ? 40.254  92.902  74.818  1.00 47.79  ? 24  ASN A CG  1 
ATOM   176   O  OD1 . ASN A 1 24  ? 40.698  92.093  75.652  1.00 39.54  ? 24  ASN A OD1 1 
ATOM   177   N  ND2 . ASN A 1 24  ? 41.037  93.764  74.156  1.00 44.78  ? 24  ASN A ND2 1 
ATOM   178   N  N   . ALA A 1 25  ? 36.010  90.626  73.708  1.00 46.69  ? 25  ALA A N   1 
ATOM   179   C  CA  . ALA A 1 25  ? 34.588  90.650  73.384  1.00 51.16  ? 25  ALA A CA  1 
ATOM   180   C  C   . ALA A 1 25  ? 33.687  90.224  74.536  1.00 53.45  ? 25  ALA A C   1 
ATOM   181   O  O   . ALA A 1 25  ? 32.473  90.447  74.463  1.00 56.60  ? 25  ALA A O   1 
ATOM   182   C  CB  . ALA A 1 25  ? 34.299  89.750  72.178  1.00 48.13  ? 25  ALA A CB  1 
ATOM   183   N  N   . GLY A 1 26  ? 34.236  89.614  75.585  1.00 50.28  ? 26  GLY A N   1 
ATOM   184   C  CA  . GLY A 1 26  ? 33.423  89.135  76.686  1.00 49.59  ? 26  GLY A CA  1 
ATOM   185   C  C   . GLY A 1 26  ? 33.794  87.744  77.167  1.00 53.02  ? 26  GLY A C   1 
ATOM   186   O  O   . GLY A 1 26  ? 34.502  87.007  76.472  1.00 48.01  ? 26  GLY A O   1 
ATOM   187   N  N   . LEU A 1 27  ? 33.298  87.365  78.348  1.00 52.00  ? 27  LEU A N   1 
ATOM   188   C  CA  . LEU A 1 27  ? 33.700  86.134  79.021  1.00 53.41  ? 27  LEU A CA  1 
ATOM   189   C  C   . LEU A 1 27  ? 32.663  85.025  78.931  1.00 52.81  ? 27  LEU A C   1 
ATOM   190   O  O   . LEU A 1 27  ? 32.785  84.030  79.651  1.00 54.38  ? 27  LEU A O   1 
ATOM   191   C  CB  . LEU A 1 27  ? 34.020  86.418  80.494  1.00 53.44  ? 27  LEU A CB  1 
ATOM   192   C  CG  . LEU A 1 27  ? 35.241  87.300  80.761  1.00 57.75  ? 27  LEU A CG  1 
ATOM   193   C  CD1 . LEU A 1 27  ? 35.534  87.391  82.250  1.00 53.73  ? 27  LEU A CD1 1 
ATOM   194   C  CD2 . LEU A 1 27  ? 36.458  86.766  80.007  1.00 53.53  ? 27  LEU A CD2 1 
ATOM   195   N  N   . ASP A 1 28  ? 31.661  85.159  78.069  1.00 52.70  ? 28  ASP A N   1 
ATOM   196   C  CA  . ASP A 1 28  ? 30.652  84.117  77.937  1.00 53.13  ? 28  ASP A CA  1 
ATOM   197   C  C   . ASP A 1 28  ? 31.251  82.823  77.395  1.00 53.01  ? 28  ASP A C   1 
ATOM   198   O  O   . ASP A 1 28  ? 32.242  82.828  76.658  1.00 47.32  ? 28  ASP A O   1 
ATOM   199   C  CB  . ASP A 1 28  ? 29.524  84.560  77.003  1.00 57.75  ? 28  ASP A CB  1 
ATOM   200   C  CG  . ASP A 1 28  ? 28.688  85.680  77.575  1.00 58.98  ? 28  ASP A CG  1 
ATOM   201   O  OD1 . ASP A 1 28  ? 28.512  85.733  78.813  1.00 60.43  ? 28  ASP A OD1 1 
ATOM   202   O  OD2 . ASP A 1 28  ? 28.194  86.498  76.774  1.00 62.66  ? 28  ASP A OD2 1 
ATOM   203   N  N   . ASP A 1 29  ? 30.621  81.703  77.764  1.00 53.66  ? 29  ASP A N   1 
ATOM   204   C  CA  . ASP A 1 29  ? 30.904  80.409  77.155  1.00 49.87  ? 29  ASP A CA  1 
ATOM   205   C  C   . ASP A 1 29  ? 30.764  80.506  75.643  1.00 47.74  ? 29  ASP A C   1 
ATOM   206   O  O   . ASP A 1 29  ? 30.038  81.364  75.134  1.00 47.10  ? 29  ASP A O   1 
ATOM   207   C  CB  . ASP A 1 29  ? 29.963  79.319  77.682  1.00 55.73  ? 29  ASP A CB  1 
ATOM   208   C  CG  . ASP A 1 29  ? 30.305  78.862  79.087  1.00 58.65  ? 29  ASP A CG  1 
ATOM   209   O  OD1 . ASP A 1 29  ? 31.420  79.160  79.564  1.00 57.31  ? 29  ASP A OD1 1 
ATOM   210   O  OD2 . ASP A 1 29  ? 29.455  78.194  79.711  1.00 60.31  ? 29  ASP A OD2 1 
ATOM   211   N  N   . TYR A 1 30  ? 31.432  79.612  74.924  1.00 42.59  ? 30  TYR A N   1 
ATOM   212   C  CA  . TYR A 1 30  ? 31.501  79.677  73.474  1.00 43.98  ? 30  TYR A CA  1 
ATOM   213   C  C   . TYR A 1 30  ? 32.085  78.357  72.999  1.00 41.22  ? 30  TYR A C   1 
ATOM   214   O  O   . TYR A 1 30  ? 32.912  77.754  73.691  1.00 43.85  ? 30  TYR A O   1 
ATOM   215   C  CB  . TYR A 1 30  ? 32.352  80.882  73.020  1.00 48.33  ? 30  TYR A CB  1 
ATOM   216   C  CG  . TYR A 1 30  ? 32.263  81.254  71.547  1.00 46.10  ? 30  TYR A CG  1 
ATOM   217   C  CD1 . TYR A 1 30  ? 31.084  81.738  70.994  1.00 43.76  ? 30  TYR A CD1 1 
ATOM   218   C  CD2 . TYR A 1 30  ? 33.378  81.150  70.721  1.00 46.18  ? 30  TYR A CD2 1 
ATOM   219   C  CE1 . TYR A 1 30  ? 31.011  82.077  69.647  1.00 46.05  ? 30  TYR A CE1 1 
ATOM   220   C  CE2 . TYR A 1 30  ? 33.315  81.491  69.377  1.00 44.17  ? 30  TYR A CE2 1 
ATOM   221   C  CZ  . TYR A 1 30  ? 32.135  81.948  68.845  1.00 48.17  ? 30  TYR A CZ  1 
ATOM   222   O  OH  . TYR A 1 30  ? 32.097  82.292  67.512  1.00 49.78  ? 30  TYR A OH  1 
ATOM   223   N  N   . GLU A 1 31  ? 31.634  77.904  71.833  1.00 41.48  ? 31  GLU A N   1 
ATOM   224   C  CA  . GLU A 1 31  ? 32.018  76.597  71.313  1.00 42.56  ? 31  GLU A CA  1 
ATOM   225   C  C   . GLU A 1 31  ? 32.279  76.716  69.820  1.00 40.35  ? 31  GLU A C   1 
ATOM   226   O  O   . GLU A 1 31  ? 31.505  77.363  69.108  1.00 41.33  ? 31  GLU A O   1 
ATOM   227   C  CB  . GLU A 1 31  ? 30.931  75.550  71.587  1.00 40.94  ? 31  GLU A CB  1 
ATOM   228   C  CG  . GLU A 1 31  ? 31.366  74.115  71.327  1.00 42.87  ? 31  GLU A CG  1 
ATOM   229   C  CD  . GLU A 1 31  ? 30.366  73.088  71.862  1.00 47.61  ? 31  GLU A CD  1 
ATOM   230   O  OE1 . GLU A 1 31  ? 29.265  73.497  72.294  1.00 48.43  ? 31  GLU A OE1 1 
ATOM   231   O  OE2 . GLU A 1 31  ? 30.678  71.875  71.839  1.00 39.73  ? 31  GLU A OE2 1 
ATOM   232   N  N   . ILE A 1 32  ? 33.363  76.098  69.353  1.00 37.86  ? 32  ILE A N   1 
ATOM   233   C  CA  . ILE A 1 32  ? 33.817  76.276  67.974  1.00 35.04  ? 32  ILE A CA  1 
ATOM   234   C  C   . ILE A 1 32  ? 34.151  74.927  67.347  1.00 36.85  ? 32  ILE A C   1 
ATOM   235   O  O   . ILE A 1 32  ? 34.686  74.043  68.035  1.00 35.49  ? 32  ILE A O   1 
ATOM   236   C  CB  . ILE A 1 32  ? 35.034  77.214  67.910  1.00 34.36  ? 32  ILE A CB  1 
ATOM   237   C  CG1 . ILE A 1 32  ? 36.095  76.789  68.925  1.00 36.87  ? 32  ILE A CG1 1 
ATOM   238   C  CG2 . ILE A 1 32  ? 34.628  78.647  68.158  1.00 35.86  ? 32  ILE A CG2 1 
ATOM   239   C  CD1 . ILE A 1 32  ? 37.488  77.257  68.577  1.00 36.47  ? 32  ILE A CD1 1 
ATOM   240   N  N   . PRO A 1 33  ? 33.871  74.727  66.056  1.00 34.12  ? 33  PRO A N   1 
ATOM   241   C  CA  . PRO A 1 33  ? 34.312  73.498  65.388  1.00 36.19  ? 33  PRO A CA  1 
ATOM   242   C  C   . PRO A 1 33  ? 35.828  73.468  65.255  1.00 34.90  ? 33  PRO A C   1 
ATOM   243   O  O   . PRO A 1 33  ? 36.492  74.504  65.266  1.00 36.94  ? 33  PRO A O   1 
ATOM   244   C  CB  . PRO A 1 33  ? 33.636  73.584  64.013  1.00 38.55  ? 33  PRO A CB  1 
ATOM   245   C  CG  . PRO A 1 33  ? 33.514  75.074  63.752  1.00 34.47  ? 33  PRO A CG  1 
ATOM   246   C  CD  . PRO A 1 33  ? 33.257  75.687  65.115  1.00 35.54  ? 33  PRO A CD  1 
ATOM   247   N  N   . VAL A 1 34  ? 36.381  72.261  65.137  1.00 33.17  ? 34  VAL A N   1 
ATOM   248   C  CA  . VAL A 1 34  ? 37.801  72.114  64.804  1.00 29.65  ? 34  VAL A CA  1 
ATOM   249   C  C   . VAL A 1 34  ? 37.921  71.502  63.418  1.00 29.46  ? 34  VAL A C   1 
ATOM   250   O  O   . VAL A 1 34  ? 37.968  70.270  63.287  1.00 31.71  ? 34  VAL A O   1 
ATOM   251   C  CB  . VAL A 1 34  ? 38.563  71.267  65.829  1.00 30.05  ? 34  VAL A CB  1 
ATOM   252   C  CG1 . VAL A 1 34  ? 40.029  71.128  65.397  1.00 25.73  ? 34  VAL A CG1 1 
ATOM   253   C  CG2 . VAL A 1 34  ? 38.491  71.913  67.188  1.00 29.18  ? 34  VAL A CG2 1 
ATOM   254   N  N   . PRO A 1 35  ? 37.958  72.310  62.366  1.00 30.15  ? 35  PRO A N   1 
ATOM   255   C  CA  . PRO A 1 35  ? 38.063  71.753  61.016  1.00 26.58  ? 35  PRO A CA  1 
ATOM   256   C  C   . PRO A 1 35  ? 39.433  71.158  60.749  1.00 28.84  ? 35  PRO A C   1 
ATOM   257   O  O   . PRO A 1 35  ? 40.435  71.478  61.395  1.00 28.01  ? 35  PRO A O   1 
ATOM   258   C  CB  . PRO A 1 35  ? 37.807  72.960  60.104  1.00 27.09  ? 35  PRO A CB  1 
ATOM   259   C  CG  . PRO A 1 35  ? 37.092  73.956  60.978  1.00 33.29  ? 35  PRO A CG  1 
ATOM   260   C  CD  . PRO A 1 35  ? 37.675  73.755  62.351  1.00 30.73  ? 35  PRO A CD  1 
ATOM   261   N  N   . TRP A 1 36  ? 39.441  70.235  59.796  1.00 27.10  ? 36  TRP A N   1 
ATOM   262   C  CA  . TRP A 1 36  ? 40.652  69.774  59.146  1.00 25.90  ? 36  TRP A CA  1 
ATOM   263   C  C   . TRP A 1 36  ? 40.202  69.245  57.798  1.00 28.66  ? 36  TRP A C   1 
ATOM   264   O  O   . TRP A 1 36  ? 39.004  69.091  57.546  1.00 25.65  ? 36  TRP A O   1 
ATOM   265   C  CB  . TRP A 1 36  ? 41.419  68.733  59.979  1.00 25.01  ? 36  TRP A CB  1 
ATOM   266   C  CG  . TRP A 1 36  ? 40.712  67.437  60.218  1.00 28.41  ? 36  TRP A CG  1 
ATOM   267   C  CD1 . TRP A 1 36  ? 39.822  67.158  61.220  1.00 29.49  ? 36  TRP A CD1 1 
ATOM   268   C  CD2 . TRP A 1 36  ? 40.860  66.231  59.467  1.00 27.38  ? 36  TRP A CD2 1 
ATOM   269   N  NE1 . TRP A 1 36  ? 39.410  65.844  61.134  1.00 28.25  ? 36  TRP A NE1 1 
ATOM   270   C  CE2 . TRP A 1 36  ? 40.026  65.258  60.062  1.00 28.15  ? 36  TRP A CE2 1 
ATOM   271   C  CE3 . TRP A 1 36  ? 41.607  65.878  58.344  1.00 26.73  ? 36  TRP A CE3 1 
ATOM   272   C  CZ2 . TRP A 1 36  ? 39.920  63.958  59.564  1.00 31.90  ? 36  TRP A CZ2 1 
ATOM   273   C  CZ3 . TRP A 1 36  ? 41.493  64.577  57.849  1.00 30.45  ? 36  TRP A CZ3 1 
ATOM   274   C  CH2 . TRP A 1 36  ? 40.662  63.642  58.456  1.00 31.60  ? 36  TRP A CH2 1 
ATOM   275   N  N   . TYR A 1 37  ? 41.160  69.020  56.912  1.00 22.97  ? 37  TYR A N   1 
ATOM   276   C  CA  . TYR A 1 37  ? 40.790  68.833  55.521  1.00 23.15  ? 37  TYR A CA  1 
ATOM   277   C  C   . TYR A 1 37  ? 41.556  67.669  54.918  1.00 26.21  ? 37  TYR A C   1 
ATOM   278   O  O   . TYR A 1 37  ? 42.706  67.398  55.279  1.00 24.29  ? 37  TYR A O   1 
ATOM   279   C  CB  . TYR A 1 37  ? 41.027  70.116  54.709  1.00 25.28  ? 37  TYR A CB  1 
ATOM   280   C  CG  . TYR A 1 37  ? 40.532  71.362  55.424  1.00 25.53  ? 37  TYR A CG  1 
ATOM   281   C  CD1 . TYR A 1 37  ? 39.222  71.824  55.250  1.00 25.78  ? 37  TYR A CD1 1 
ATOM   282   C  CD2 . TYR A 1 37  ? 41.364  72.062  56.293  1.00 25.77  ? 37  TYR A CD2 1 
ATOM   283   C  CE1 . TYR A 1 37  ? 38.770  72.978  55.915  1.00 28.08  ? 37  TYR A CE1 1 
ATOM   284   C  CE2 . TYR A 1 37  ? 40.923  73.201  56.962  1.00 26.10  ? 37  TYR A CE2 1 
ATOM   285   C  CZ  . TYR A 1 37  ? 39.636  73.650  56.773  1.00 26.99  ? 37  TYR A CZ  1 
ATOM   286   O  OH  . TYR A 1 37  ? 39.234  74.782  57.451  1.00 30.83  ? 37  TYR A OH  1 
ATOM   287   N  N   . LEU A 1 38  ? 40.899  66.997  53.978  1.00 25.18  ? 38  LEU A N   1 
ATOM   288   C  CA  . LEU A 1 38  ? 41.504  65.968  53.145  1.00 24.58  ? 38  LEU A CA  1 
ATOM   289   C  C   . LEU A 1 38  ? 41.349  66.382  51.691  1.00 26.59  ? 38  LEU A C   1 
ATOM   290   O  O   . LEU A 1 38  ? 40.259  66.788  51.273  1.00 29.51  ? 38  LEU A O   1 
ATOM   291   C  CB  . LEU A 1 38  ? 40.843  64.600  53.374  1.00 28.42  ? 38  LEU A CB  1 
ATOM   292   C  CG  . LEU A 1 38  ? 41.222  63.476  52.398  1.00 30.48  ? 38  LEU A CG  1 
ATOM   293   C  CD1 . LEU A 1 38  ? 42.592  62.916  52.744  1.00 27.09  ? 38  LEU A CD1 1 
ATOM   294   C  CD2 . LEU A 1 38  ? 40.155  62.363  52.390  1.00 28.15  ? 38  LEU A CD2 1 
ATOM   295   N  N   . ILE A 1 39  ? 42.434  66.306  50.936  1.00 21.86  ? 39  ILE A N   1 
ATOM   296   C  CA  . ILE A 1 39  ? 42.406  66.488  49.494  1.00 28.08  ? 39  ILE A CA  1 
ATOM   297   C  C   . ILE A 1 39  ? 42.819  65.161  48.876  1.00 30.07  ? 39  ILE A C   1 
ATOM   298   O  O   . ILE A 1 39  ? 43.950  64.701  49.080  1.00 27.27  ? 39  ILE A O   1 
ATOM   299   C  CB  . ILE A 1 39  ? 43.330  67.622  49.020  1.00 29.04  ? 39  ILE A CB  1 
ATOM   300   C  CG1 . ILE A 1 39  ? 42.808  68.982  49.477  1.00 24.00  ? 39  ILE A CG1 1 
ATOM   301   C  CG2 . ILE A 1 39  ? 43.453  67.585  47.521  1.00 26.15  ? 39  ILE A CG2 1 
ATOM   302   C  CD1 . ILE A 1 39  ? 43.202  69.345  50.901  1.00 28.45  ? 39  ILE A CD1 1 
ATOM   303   N  N   . THR A 1 40  ? 41.904  64.518  48.149  1.00 29.18  ? 40  THR A N   1 
ATOM   304   C  CA  . THR A 1 40  ? 42.254  63.329  47.383  1.00 32.91  ? 40  THR A CA  1 
ATOM   305   C  C   . THR A 1 40  ? 42.750  63.814  46.028  1.00 33.79  ? 40  THR A C   1 
ATOM   306   O  O   . THR A 1 40  ? 42.159  64.715  45.432  1.00 37.91  ? 40  THR A O   1 
ATOM   307   C  CB  . THR A 1 40  ? 41.063  62.360  47.239  1.00 32.02  ? 40  THR A CB  1 
ATOM   308   O  OG1 . THR A 1 40  ? 39.982  62.987  46.528  1.00 32.72  ? 40  THR A OG1 1 
ATOM   309   C  CG2 . THR A 1 40  ? 40.552  61.899  48.608  1.00 33.50  ? 40  THR A CG2 1 
ATOM   310   N  N   . HIS A 1 41  ? 43.859  63.255  45.564  1.00 37.33  ? 41  HIS A N   1 
ATOM   311   C  CA  . HIS A 1 41  ? 44.480  63.778  44.367  1.00 35.84  ? 41  HIS A CA  1 
ATOM   312   C  C   . HIS A 1 41  ? 45.086  62.586  43.646  1.00 32.14  ? 41  HIS A C   1 
ATOM   313   O  O   . HIS A 1 41  ? 45.603  61.678  44.309  1.00 35.44  ? 41  HIS A O   1 
ATOM   314   C  CB  . HIS A 1 41  ? 45.549  64.821  44.730  1.00 35.74  ? 41  HIS A CB  1 
ATOM   315   C  CG  . HIS A 1 41  ? 46.185  65.509  43.559  1.00 31.96  ? 41  HIS A CG  1 
ATOM   316   N  ND1 . HIS A 1 41  ? 47.075  64.880  42.717  1.00 31.92  ? 41  HIS A ND1 1 
ATOM   317   C  CD2 . HIS A 1 41  ? 46.105  66.793  43.128  1.00 35.15  ? 41  HIS A CD2 1 
ATOM   318   C  CE1 . HIS A 1 41  ? 47.499  65.738  41.801  1.00 34.81  ? 41  HIS A CE1 1 
ATOM   319   N  NE2 . HIS A 1 41  ? 46.929  66.909  42.030  1.00 30.11  ? 41  HIS A NE2 1 
ATOM   320   N  N   . PRO A 1 42  ? 44.999  62.536  42.315  1.00 33.25  ? 42  PRO A N   1 
ATOM   321   C  CA  . PRO A 1 42  ? 45.632  61.433  41.569  1.00 35.64  ? 42  PRO A CA  1 
ATOM   322   C  C   . PRO A 1 42  ? 47.064  61.144  41.992  1.00 36.48  ? 42  PRO A C   1 
ATOM   323   O  O   . PRO A 1 42  ? 47.478  59.982  42.007  1.00 35.45  ? 42  PRO A O   1 
ATOM   324   C  CB  . PRO A 1 42  ? 45.576  61.917  40.111  1.00 33.82  ? 42  PRO A CB  1 
ATOM   325   C  CG  . PRO A 1 42  ? 44.498  62.909  40.053  1.00 38.80  ? 42  PRO A CG  1 
ATOM   326   C  CD  . PRO A 1 42  ? 44.181  63.397  41.450  1.00 36.67  ? 42  PRO A CD  1 
ATOM   327   N  N   . LYS A 1 43  ? 47.840  62.168  42.335  1.00 35.25  ? 43  LYS A N   1 
ATOM   328   C  CA  . LYS A 1 43  ? 49.227  61.956  42.712  1.00 35.27  ? 43  LYS A CA  1 
ATOM   329   C  C   . LYS A 1 43  ? 49.407  61.637  44.195  1.00 32.06  ? 43  LYS A C   1 
ATOM   330   O  O   . LYS A 1 43  ? 50.538  61.435  44.636  1.00 29.82  ? 43  LYS A O   1 
ATOM   331   C  CB  . LYS A 1 43  ? 50.056  63.174  42.311  1.00 36.87  ? 43  LYS A CB  1 
ATOM   332   C  CG  . LYS A 1 43  ? 50.446  63.178  40.824  1.00 38.18  ? 43  LYS A CG  1 
ATOM   333   C  CD  . LYS A 1 43  ? 51.113  64.490  40.434  1.00 46.13  ? 43  LYS A CD  1 
ATOM   334   C  CE  . LYS A 1 43  ? 51.585  64.494  38.984  1.00 57.33  ? 43  LYS A CE  1 
ATOM   335   N  NZ  . LYS A 1 43  ? 52.621  65.567  38.765  1.00 63.42  ? 43  LYS A NZ  1 
ATOM   336   N  N   . GLY A 1 44  ? 48.342  61.556  44.970  1.00 31.05  ? 44  GLY A N   1 
ATOM   337   C  CA  . GLY A 1 44  ? 48.459  61.171  46.364  1.00 28.20  ? 44  GLY A CA  1 
ATOM   338   C  C   . GLY A 1 44  ? 47.537  62.001  47.231  1.00 33.75  ? 44  GLY A C   1 
ATOM   339   O  O   . GLY A 1 44  ? 47.099  63.090  46.860  1.00 36.86  ? 44  GLY A O   1 
ATOM   340   N  N   . ASN A 1 45  ? 47.250  61.478  48.422  1.00 29.53  ? 45  ASN A N   1 
ATOM   341   C  CA  . ASN A 1 45  ? 46.315  62.113  49.337  1.00 29.62  ? 45  ASN A CA  1 
ATOM   342   C  C   . ASN A 1 45  ? 47.032  63.113  50.244  1.00 25.79  ? 45  ASN A C   1 
ATOM   343   O  O   . ASN A 1 45  ? 48.165  62.893  50.671  1.00 24.78  ? 45  ASN A O   1 
ATOM   344   C  CB  . ASN A 1 45  ? 45.599  61.059  50.188  1.00 26.20  ? 45  ASN A CB  1 
ATOM   345   C  CG  . ASN A 1 45  ? 44.740  60.109  49.347  1.00 34.62  ? 45  ASN A CG  1 
ATOM   346   O  OD1 . ASN A 1 45  ? 43.937  60.550  48.527  1.00 35.98  ? 45  ASN A OD1 1 
ATOM   347   N  ND2 . ASN A 1 45  ? 44.920  58.807  49.543  1.00 31.99  ? 45  ASN A ND2 1 
ATOM   348   N  N   . VAL A 1 46  ? 46.337  64.204  50.567  1.00 25.66  ? 46  VAL A N   1 
ATOM   349   C  CA  . VAL A 1 46  ? 46.879  65.271  51.401  1.00 26.09  ? 46  VAL A CA  1 
ATOM   350   C  C   . VAL A 1 46  ? 45.978  65.457  52.615  1.00 22.33  ? 46  VAL A C   1 
ATOM   351   O  O   . VAL A 1 46  ? 44.753  65.560  52.478  1.00 25.58  ? 46  VAL A O   1 
ATOM   352   C  CB  . VAL A 1 46  ? 47.013  66.591  50.618  1.00 27.05  ? 46  VAL A CB  1 
ATOM   353   C  CG1 . VAL A 1 46  ? 47.727  67.671  51.467  1.00 21.32  ? 46  VAL A CG1 1 
ATOM   354   C  CG2 . VAL A 1 46  ? 47.733  66.355  49.303  1.00 24.16  ? 46  VAL A CG2 1 
ATOM   355   N  N   . VAL A 1 47  ? 46.584  65.492  53.796  1.00 22.32  ? 47  VAL A N   1 
ATOM   356   C  CA  . VAL A 1 47  ? 45.909  65.881  55.033  1.00 22.86  ? 47  VAL A CA  1 
ATOM   357   C  C   . VAL A 1 47  ? 46.438  67.251  55.457  1.00 24.95  ? 47  VAL A C   1 
ATOM   358   O  O   . VAL A 1 47  ? 47.657  67.458  55.526  1.00 23.68  ? 47  VAL A O   1 
ATOM   359   C  CB  . VAL A 1 47  ? 46.133  64.844  56.156  1.00 23.03  ? 47  VAL A CB  1 
ATOM   360   C  CG1 . VAL A 1 47  ? 45.709  65.406  57.501  1.00 20.11  ? 47  VAL A CG1 1 
ATOM   361   C  CG2 . VAL A 1 47  ? 45.404  63.548  55.871  1.00 26.71  ? 47  VAL A CG2 1 
ATOM   362   N  N   . ILE A 1 48  ? 45.533  68.161  55.805  1.00 20.67  ? 48  ILE A N   1 
ATOM   363   C  CA  . ILE A 1 48  ? 45.895  69.468  56.338  1.00 21.72  ? 48  ILE A CA  1 
ATOM   364   C  C   . ILE A 1 48  ? 45.543  69.481  57.826  1.00 25.14  ? 48  ILE A C   1 
ATOM   365   O  O   . ILE A 1 48  ? 44.355  69.409  58.192  1.00 26.69  ? 48  ILE A O   1 
ATOM   366   C  CB  . ILE A 1 48  ? 45.182  70.608  55.588  1.00 23.35  ? 48  ILE A CB  1 
ATOM   367   C  CG1 . ILE A 1 48  ? 45.530  70.593  54.094  1.00 22.03  ? 48  ILE A CG1 1 
ATOM   368   C  CG2 . ILE A 1 48  ? 45.557  71.947  56.179  1.00 22.20  ? 48  ILE A CG2 1 
ATOM   369   C  CD1 . ILE A 1 48  ? 44.913  71.785  53.325  1.00 22.36  ? 48  ILE A CD1 1 
ATOM   370   N  N   . ASP A 1 49  ? 46.581  69.543  58.679  1.00 19.50  ? 49  ASP A N   1 
ATOM   371   C  CA  . ASP A 1 49  ? 46.498  69.731  60.132  1.00 22.90  ? 49  ASP A CA  1 
ATOM   372   C  C   . ASP A 1 49  ? 46.041  68.495  60.927  1.00 25.92  ? 49  ASP A C   1 
ATOM   373   O  O   . ASP A 1 49  ? 46.753  68.056  61.841  1.00 25.64  ? 49  ASP A O   1 
ATOM   374   C  CB  . ASP A 1 49  ? 45.588  70.920  60.468  1.00 21.55  ? 49  ASP A CB  1 
ATOM   375   C  CG  . ASP A 1 49  ? 46.239  72.249  60.161  1.00 24.39  ? 49  ASP A CG  1 
ATOM   376   O  OD1 . ASP A 1 49  ? 47.488  72.290  59.889  1.00 20.69  ? 49  ASP A OD1 1 
ATOM   377   O  OD2 . ASP A 1 49  ? 45.490  73.256  60.186  1.00 23.25  ? 49  ASP A OD2 1 
ATOM   378   N  N   . GLY A 1 50  ? 44.849  67.949  60.627  1.00 23.44  ? 50  GLY A N   1 
ATOM   379   C  CA  . GLY A 1 50  ? 44.353  66.761  61.304  1.00 26.08  ? 50  GLY A CA  1 
ATOM   380   C  C   . GLY A 1 50  ? 43.525  67.000  62.555  1.00 27.79  ? 50  GLY A C   1 
ATOM   381   O  O   . GLY A 1 50  ? 43.066  66.029  63.171  1.00 29.73  ? 50  GLY A O   1 
ATOM   382   N  N   . GLY A 1 51  ? 43.317  68.246  62.956  1.00 26.16  ? 51  GLY A N   1 
ATOM   383   C  CA  . GLY A 1 51  ? 42.483  68.520  64.111  1.00 25.40  ? 51  GLY A CA  1 
ATOM   384   C  C   . GLY A 1 51  ? 43.210  68.292  65.423  1.00 27.35  ? 51  GLY A C   1 
ATOM   385   O  O   . GLY A 1 51  ? 44.451  68.276  65.500  1.00 28.24  ? 51  GLY A O   1 
ATOM   386   N  N   . CYS A 1 52  ? 42.418  68.128  66.482  1.00 26.10  ? 52  CYS A N   1 
ATOM   387   C  CA  . CYS A 1 52  ? 42.990  67.753  67.768  1.00 30.72  ? 52  CYS A CA  1 
ATOM   388   C  C   . CYS A 1 52  ? 43.455  66.301  67.731  1.00 30.58  ? 52  CYS A C   1 
ATOM   389   O  O   . CYS A 1 52  ? 42.897  65.463  67.018  1.00 27.34  ? 52  CYS A O   1 
ATOM   390   C  CB  . CYS A 1 52  ? 41.978  67.960  68.897  1.00 28.24  ? 52  CYS A CB  1 
ATOM   391   S  SG  . CYS A 1 52  ? 41.271  69.624  68.925  1.00 28.92  ? 52  CYS A SG  1 
ATOM   392   N  N   . ALA A 1 53  ? 44.518  66.022  68.483  1.00 27.84  ? 53  ALA A N   1 
ATOM   393   C  CA  . ALA A 1 53  ? 45.026  64.662  68.569  1.00 26.96  ? 53  ALA A CA  1 
ATOM   394   C  C   . ALA A 1 53  ? 43.937  63.729  69.083  1.00 32.54  ? 53  ALA A C   1 
ATOM   395   O  O   . ALA A 1 53  ? 43.154  64.091  69.972  1.00 27.88  ? 53  ALA A O   1 
ATOM   396   C  CB  . ALA A 1 53  ? 46.245  64.607  69.493  1.00 32.15  ? 53  ALA A CB  1 
ATOM   397   N  N   . VAL A 1 54  ? 43.883  62.521  68.507  1.00 31.56  ? 54  VAL A N   1 
ATOM   398   C  CA  . VAL A 1 54  ? 42.890  61.538  68.943  1.00 34.40  ? 54  VAL A CA  1 
ATOM   399   C  C   . VAL A 1 54  ? 42.991  61.289  70.448  1.00 34.02  ? 54  VAL A C   1 
ATOM   400   O  O   . VAL A 1 54  ? 41.970  61.066  71.113  1.00 35.87  ? 54  VAL A O   1 
ATOM   401   C  CB  . VAL A 1 54  ? 43.020  60.226  68.135  1.00 36.71  ? 54  VAL A CB  1 
ATOM   402   C  CG1 . VAL A 1 54  ? 44.307  59.466  68.491  1.00 29.90  ? 54  VAL A CG1 1 
ATOM   403   C  CG2 . VAL A 1 54  ? 41.786  59.351  68.368  1.00 34.04  ? 54  VAL A CG2 1 
ATOM   404   N  N   . GLU A 1 55  ? 44.201  61.379  71.018  1.00 31.49  ? 55  GLU A N   1 
ATOM   405   C  CA  . GLU A 1 55  ? 44.374  61.185  72.456  1.00 37.51  ? 55  GLU A CA  1 
ATOM   406   C  C   . GLU A 1 55  ? 43.475  62.108  73.280  1.00 39.63  ? 55  GLU A C   1 
ATOM   407   O  O   . GLU A 1 55  ? 43.157  61.772  74.426  1.00 38.99  ? 55  GLU A O   1 
ATOM   408   C  CB  . GLU A 1 55  ? 45.846  61.388  72.860  1.00 36.37  ? 55  GLU A CB  1 
ATOM   409   C  CG  . GLU A 1 55  ? 46.858  60.311  72.366  1.00 35.25  ? 55  GLU A CG  1 
ATOM   410   C  CD  . GLU A 1 55  ? 47.319  60.513  70.914  1.00 41.69  ? 55  GLU A CD  1 
ATOM   411   O  OE1 . GLU A 1 55  ? 46.729  61.340  70.174  1.00 37.91  ? 55  GLU A OE1 1 
ATOM   412   O  OE2 . GLU A 1 55  ? 48.285  59.839  70.505  1.00 42.54  ? 55  GLU A OE2 1 
ATOM   413   N  N   . CYS A 1 56  ? 43.047  63.248  72.717  1.00 36.02  ? 56  CYS A N   1 
ATOM   414   C  CA  . CYS A 1 56  ? 42.130  64.159  73.404  1.00 38.46  ? 56  CYS A CA  1 
ATOM   415   C  C   . CYS A 1 56  ? 40.735  63.575  73.598  1.00 40.43  ? 56  CYS A C   1 
ATOM   416   O  O   . CYS A 1 56  ? 39.986  64.062  74.451  1.00 36.97  ? 56  CYS A O   1 
ATOM   417   C  CB  . CYS A 1 56  ? 41.999  65.479  72.633  1.00 35.24  ? 56  CYS A CB  1 
ATOM   418   S  SG  . CYS A 1 56  ? 43.548  66.349  72.473  1.00 41.94  ? 56  CYS A SG  1 
ATOM   419   N  N   . ALA A 1 57  ? 40.354  62.580  72.800  1.00 39.81  ? 57  ALA A N   1 
ATOM   420   C  CA  . ALA A 1 57  ? 39.060  61.942  72.998  1.00 43.58  ? 57  ALA A CA  1 
ATOM   421   C  C   . ALA A 1 57  ? 39.017  61.128  74.290  1.00 42.81  ? 57  ALA A C   1 
ATOM   422   O  O   . ALA A 1 57  ? 37.950  60.995  74.899  1.00 45.65  ? 57  ALA A O   1 
ATOM   423   C  CB  . ALA A 1 57  ? 38.734  61.062  71.794  1.00 38.67  ? 57  ALA A CB  1 
ATOM   424   N  N   . SER A 1 58  ? 40.158  60.598  74.730  1.00 40.89  ? 58  SER A N   1 
ATOM   425   C  CA  . SER A 1 58  ? 40.245  59.743  75.912  1.00 38.60  ? 58  SER A CA  1 
ATOM   426   C  C   . SER A 1 58  ? 40.807  60.452  77.136  1.00 40.93  ? 58  SER A C   1 
ATOM   427   O  O   . SER A 1 58  ? 40.258  60.310  78.230  1.00 44.94  ? 58  SER A O   1 
ATOM   428   C  CB  . SER A 1 58  ? 41.105  58.511  75.614  1.00 33.34  ? 58  SER A CB  1 
ATOM   429   O  OG  . SER A 1 58  ? 40.474  57.700  74.645  1.00 41.56  ? 58  SER A OG  1 
ATOM   430   N  N   . ASP A 1 59  ? 41.901  61.197  76.995  1.00 38.24  ? 59  ASP A N   1 
ATOM   431   C  CA  . ASP A 1 59  ? 42.597  61.769  78.146  1.00 39.14  ? 59  ASP A CA  1 
ATOM   432   C  C   . ASP A 1 59  ? 43.086  63.180  77.837  1.00 40.51  ? 59  ASP A C   1 
ATOM   433   O  O   . ASP A 1 59  ? 44.294  63.441  77.777  1.00 39.05  ? 59  ASP A O   1 
ATOM   434   C  CB  . ASP A 1 59  ? 43.750  60.859  78.578  1.00 33.47  ? 59  ASP A CB  1 
ATOM   435   C  CG  . ASP A 1 59  ? 44.364  61.293  79.882  1.00 41.39  ? 59  ASP A CG  1 
ATOM   436   O  OD1 . ASP A 1 59  ? 43.724  62.101  80.595  1.00 40.70  ? 59  ASP A OD1 1 
ATOM   437   O  OD2 . ASP A 1 59  ? 45.487  60.842  80.193  1.00 50.77  ? 59  ASP A OD2 1 
ATOM   438   N  N   . PRO A 1 60  ? 42.162  64.134  77.691  1.00 42.11  ? 60  PRO A N   1 
ATOM   439   C  CA  . PRO A 1 60  ? 42.581  65.515  77.367  1.00 43.23  ? 60  PRO A CA  1 
ATOM   440   C  C   . PRO A 1 60  ? 43.559  66.110  78.365  1.00 44.63  ? 60  PRO A C   1 
ATOM   441   O  O   . PRO A 1 60  ? 44.608  66.642  77.962  1.00 40.97  ? 60  PRO A O   1 
ATOM   442   C  CB  . PRO A 1 60  ? 41.257  66.297  77.352  1.00 41.21  ? 60  PRO A CB  1 
ATOM   443   C  CG  . PRO A 1 60  ? 40.174  65.299  77.318  1.00 42.30  ? 60  PRO A CG  1 
ATOM   444   C  CD  . PRO A 1 60  ? 40.702  63.996  77.825  1.00 42.36  ? 60  PRO A CD  1 
ATOM   445   N  N   . LYS A 1 61  ? 43.233  66.047  79.663  1.00 45.82  ? 61  LYS A N   1 
ATOM   446   C  CA  . LYS A 1 61  ? 44.110  66.604  80.690  1.00 40.74  ? 61  LYS A CA  1 
ATOM   447   C  C   . LYS A 1 61  ? 45.484  65.960  80.656  1.00 40.77  ? 61  LYS A C   1 
ATOM   448   O  O   . LYS A 1 61  ? 46.498  66.634  80.866  1.00 43.27  ? 61  LYS A O   1 
ATOM   449   C  CB  . LYS A 1 61  ? 43.478  66.440  82.069  1.00 47.34  ? 61  LYS A CB  1 
ATOM   450   C  CG  . LYS A 1 61  ? 42.281  67.347  82.309  1.00 51.91  ? 61  LYS A CG  1 
ATOM   451   C  CD  . LYS A 1 61  ? 41.673  67.130  83.695  1.00 62.20  ? 61  LYS A CD  1 
ATOM   452   C  CE  . LYS A 1 61  ? 40.397  67.957  83.884  1.00 62.30  ? 61  LYS A CE  1 
ATOM   453   N  NZ  . LYS A 1 61  ? 39.278  67.158  84.474  1.00 63.95  ? 61  LYS A NZ  1 
ATOM   454   N  N   . GLY A 1 62  ? 45.549  64.664  80.377  1.00 38.85  ? 62  GLY A N   1 
ATOM   455   C  CA  . GLY A 1 62  ? 46.843  64.008  80.350  1.00 41.95  ? 62  GLY A CA  1 
ATOM   456   C  C   . GLY A 1 62  ? 47.666  64.386  79.133  1.00 42.54  ? 62  GLY A C   1 
ATOM   457   O  O   . GLY A 1 62  ? 48.891  64.504  79.214  1.00 38.23  ? 62  GLY A O   1 
ATOM   458   N  N   . TYR A 1 63  ? 47.012  64.586  77.991  1.00 38.73  ? 63  TYR A N   1 
ATOM   459   C  CA  . TYR A 1 63  ? 47.769  64.809  76.768  1.00 37.15  ? 63  TYR A CA  1 
ATOM   460   C  C   . TYR A 1 63  ? 48.034  66.284  76.489  1.00 35.87  ? 63  TYR A C   1 
ATOM   461   O  O   . TYR A 1 63  ? 49.106  66.612  75.975  1.00 34.00  ? 63  TYR A O   1 
ATOM   462   C  CB  . TYR A 1 63  ? 47.060  64.158  75.580  1.00 31.68  ? 63  TYR A CB  1 
ATOM   463   C  CG  . TYR A 1 63  ? 47.948  64.026  74.363  1.00 35.15  ? 63  TYR A CG  1 
ATOM   464   C  CD1 . TYR A 1 63  ? 48.985  63.099  74.326  1.00 31.72  ? 63  TYR A CD1 1 
ATOM   465   C  CD2 . TYR A 1 63  ? 47.747  64.834  73.239  1.00 34.82  ? 63  TYR A CD2 1 
ATOM   466   C  CE1 . TYR A 1 63  ? 49.797  62.976  73.200  1.00 35.44  ? 63  TYR A CE1 1 
ATOM   467   C  CE2 . TYR A 1 63  ? 48.552  64.721  72.112  1.00 31.68  ? 63  TYR A CE2 1 
ATOM   468   C  CZ  . TYR A 1 63  ? 49.577  63.805  72.092  1.00 35.38  ? 63  TYR A CZ  1 
ATOM   469   O  OH  . TYR A 1 63  ? 50.368  63.718  70.955  1.00 32.08  ? 63  TYR A OH  1 
ATOM   470   N  N   . TRP A 1 64  ? 47.110  67.182  76.844  1.00 37.66  ? 64  TRP A N   1 
ATOM   471   C  CA  . TRP A 1 64  ? 47.289  68.620  76.656  1.00 32.61  ? 64  TRP A CA  1 
ATOM   472   C  C   . TRP A 1 64  ? 47.716  69.363  77.918  1.00 37.30  ? 64  TRP A C   1 
ATOM   473   O  O   . TRP A 1 64  ? 48.304  70.445  77.816  1.00 34.72  ? 64  TRP A O   1 
ATOM   474   C  CB  . TRP A 1 64  ? 45.990  69.261  76.154  1.00 30.36  ? 64  TRP A CB  1 
ATOM   475   C  CG  . TRP A 1 64  ? 45.719  69.140  74.684  1.00 28.30  ? 64  TRP A CG  1 
ATOM   476   C  CD1 . TRP A 1 64  ? 46.463  68.476  73.759  1.00 27.35  ? 64  TRP A CD1 1 
ATOM   477   C  CD2 . TRP A 1 64  ? 44.621  69.719  73.976  1.00 28.27  ? 64  TRP A CD2 1 
ATOM   478   N  NE1 . TRP A 1 64  ? 45.897  68.598  72.520  1.00 26.90  ? 64  TRP A NE1 1 
ATOM   479   C  CE2 . TRP A 1 64  ? 44.765  69.362  72.622  1.00 29.12  ? 64  TRP A CE2 1 
ATOM   480   C  CE3 . TRP A 1 64  ? 43.531  70.518  74.358  1.00 28.74  ? 64  TRP A CE3 1 
ATOM   481   C  CZ2 . TRP A 1 64  ? 43.857  69.763  71.638  1.00 28.99  ? 64  TRP A CZ2 1 
ATOM   482   C  CZ3 . TRP A 1 64  ? 42.623  70.922  73.385  1.00 28.89  ? 64  TRP A CZ3 1 
ATOM   483   C  CH2 . TRP A 1 64  ? 42.795  70.541  72.034  1.00 31.48  ? 64  TRP A CH2 1 
ATOM   484   N  N   . GLY A 1 65  ? 47.394  68.849  79.106  1.00 39.26  ? 65  GLY A N   1 
ATOM   485   C  CA  . GLY A 1 65  ? 47.776  69.536  80.326  1.00 35.39  ? 65  GLY A CA  1 
ATOM   486   C  C   . GLY A 1 65  ? 46.900  70.743  80.623  1.00 34.96  ? 65  GLY A C   1 
ATOM   487   O  O   . GLY A 1 65  ? 45.735  70.816  80.225  1.00 38.72  ? 65  GLY A O   1 
ATOM   488   N  N   . ASP A 1 66  ? 47.502  71.725  81.298  1.00 32.44  ? 66  ASP A N   1 
ATOM   489   C  CA  . ASP A 1 66  ? 46.761  72.832  81.892  1.00 35.94  ? 66  ASP A CA  1 
ATOM   490   C  C   . ASP A 1 66  ? 45.986  73.662  80.875  1.00 38.85  ? 66  ASP A C   1 
ATOM   491   O  O   . ASP A 1 66  ? 45.006  74.317  81.250  1.00 37.41  ? 66  ASP A O   1 
ATOM   492   C  CB  . ASP A 1 66  ? 47.718  73.744  82.663  1.00 41.68  ? 66  ASP A CB  1 
ATOM   493   C  CG  . ASP A 1 66  ? 48.402  73.035  83.815  1.00 46.37  ? 66  ASP A CG  1 
ATOM   494   O  OD1 . ASP A 1 66  ? 47.749  72.203  84.475  1.00 48.11  ? 66  ASP A OD1 1 
ATOM   495   O  OD2 . ASP A 1 66  ? 49.592  73.315  84.066  1.00 51.08  ? 66  ASP A OD2 1 
ATOM   496   N  N   . ILE A 1 67  ? 46.404  73.673  79.608  1.00 37.24  ? 67  ILE A N   1 
ATOM   497   C  CA  . ILE A 1 67  ? 45.708  74.482  78.616  1.00 38.83  ? 67  ILE A CA  1 
ATOM   498   C  C   . ILE A 1 67  ? 44.239  74.090  78.509  1.00 39.16  ? 67  ILE A C   1 
ATOM   499   O  O   . ILE A 1 67  ? 43.425  74.878  78.014  1.00 38.01  ? 67  ILE A O   1 
ATOM   500   C  CB  . ILE A 1 67  ? 46.417  74.371  77.250  1.00 33.93  ? 67  ILE A CB  1 
ATOM   501   C  CG1 . ILE A 1 67  ? 45.868  75.411  76.272  1.00 33.07  ? 67  ILE A CG1 1 
ATOM   502   C  CG2 . ILE A 1 67  ? 46.283  72.964  76.687  1.00 30.70  ? 67  ILE A CG2 1 
ATOM   503   C  CD1 . ILE A 1 67  ? 46.049  76.836  76.733  1.00 39.34  ? 67  ILE A CD1 1 
ATOM   504   N  N   . THR A 1 68  ? 43.873  72.895  78.993  1.00 38.83  ? 68  THR A N   1 
ATOM   505   C  CA  . THR A 1 68  ? 42.484  72.440  78.927  1.00 39.66  ? 68  THR A CA  1 
ATOM   506   C  C   . THR A 1 68  ? 41.542  73.313  79.731  1.00 42.90  ? 68  THR A C   1 
ATOM   507   O  O   . THR A 1 68  ? 40.341  73.327  79.446  1.00 45.67  ? 68  THR A O   1 
ATOM   508   C  CB  . THR A 1 68  ? 42.364  71.010  79.431  1.00 41.80  ? 68  THR A CB  1 
ATOM   509   O  OG1 . THR A 1 68  ? 43.078  70.887  80.667  1.00 41.61  ? 68  THR A OG1 1 
ATOM   510   C  CG2 . THR A 1 68  ? 42.929  70.058  78.424  1.00 34.94  ? 68  THR A CG2 1 
ATOM   511   N  N   . SER A 1 69  ? 42.050  74.023  80.741  1.00 41.46  ? 69  SER A N   1 
ATOM   512   C  CA  . SER A 1 69  ? 41.242  75.010  81.441  1.00 41.75  ? 69  SER A CA  1 
ATOM   513   C  C   . SER A 1 69  ? 40.860  76.188  80.555  1.00 46.15  ? 69  SER A C   1 
ATOM   514   O  O   . SER A 1 69  ? 40.001  76.981  80.949  1.00 52.41  ? 69  SER A O   1 
ATOM   515   C  CB  . SER A 1 69  ? 41.985  75.521  82.674  1.00 41.09  ? 69  SER A CB  1 
ATOM   516   O  OG  . SER A 1 69  ? 43.090  76.327  82.293  1.00 46.66  ? 69  SER A OG  1 
ATOM   517   N  N   . VAL A 1 70  ? 41.473  76.334  79.382  1.00 47.36  ? 70  VAL A N   1 
ATOM   518   C  CA  . VAL A 1 70  ? 41.141  77.399  78.441  1.00 43.40  ? 70  VAL A CA  1 
ATOM   519   C  C   . VAL A 1 70  ? 40.407  76.850  77.224  1.00 41.80  ? 70  VAL A C   1 
ATOM   520   O  O   . VAL A 1 70  ? 39.385  77.396  76.800  1.00 37.17  ? 70  VAL A O   1 
ATOM   521   C  CB  . VAL A 1 70  ? 42.406  78.179  78.018  1.00 42.49  ? 70  VAL A CB  1 
ATOM   522   C  CG1 . VAL A 1 70  ? 42.093  79.097  76.868  1.00 41.83  ? 70  VAL A CG1 1 
ATOM   523   C  CG2 . VAL A 1 70  ? 42.974  78.967  79.204  1.00 41.62  ? 70  VAL A CG2 1 
ATOM   524   N  N   . TYR A 1 71  ? 40.912  75.761  76.654  1.00 38.14  ? 71  TYR A N   1 
ATOM   525   C  CA  . TYR A 1 71  ? 40.270  75.105  75.520  1.00 42.53  ? 71  TYR A CA  1 
ATOM   526   C  C   . TYR A 1 71  ? 39.981  73.674  75.927  1.00 42.16  ? 71  TYR A C   1 
ATOM   527   O  O   . TYR A 1 71  ? 40.908  72.864  76.053  1.00 34.53  ? 71  TYR A O   1 
ATOM   528   C  CB  . TYR A 1 71  ? 41.140  75.136  74.265  1.00 40.40  ? 71  TYR A CB  1 
ATOM   529   C  CG  . TYR A 1 71  ? 41.529  76.519  73.800  1.00 42.06  ? 71  TYR A CG  1 
ATOM   530   C  CD1 . TYR A 1 71  ? 40.662  77.286  73.024  1.00 41.01  ? 71  TYR A CD1 1 
ATOM   531   C  CD2 . TYR A 1 71  ? 42.775  77.040  74.103  1.00 42.81  ? 71  TYR A CD2 1 
ATOM   532   C  CE1 . TYR A 1 71  ? 41.021  78.538  72.578  1.00 38.76  ? 71  TYR A CE1 1 
ATOM   533   C  CE2 . TYR A 1 71  ? 43.150  78.294  73.661  1.00 41.28  ? 71  TYR A CE2 1 
ATOM   534   C  CZ  . TYR A 1 71  ? 42.273  79.041  72.904  1.00 45.62  ? 71  TYR A CZ  1 
ATOM   535   O  OH  . TYR A 1 71  ? 42.658  80.296  72.474  1.00 45.74  ? 71  TYR A OH  1 
ATOM   536   N  N   . TRP A 1 72  ? 38.697  73.368  76.138  1.00 42.43  ? 72  TRP A N   1 
ATOM   537   C  CA  . TRP A 1 72  ? 38.304  72.011  76.470  1.00 40.01  ? 72  TRP A CA  1 
ATOM   538   C  C   . TRP A 1 72  ? 37.853  71.289  75.215  1.00 36.88  ? 72  TRP A C   1 
ATOM   539   O  O   . TRP A 1 72  ? 36.831  71.675  74.619  1.00 39.62  ? 72  TRP A O   1 
ATOM   540   C  CB  . TRP A 1 72  ? 37.191  71.985  77.509  1.00 40.49  ? 72  TRP A CB  1 
ATOM   541   C  CG  . TRP A 1 72  ? 36.911  70.591  77.867  1.00 39.54  ? 72  TRP A CG  1 
ATOM   542   C  CD1 . TRP A 1 72  ? 35.881  69.809  77.414  1.00 36.98  ? 72  TRP A CD1 1 
ATOM   543   C  CD2 . TRP A 1 72  ? 37.720  69.757  78.699  1.00 43.20  ? 72  TRP A CD2 1 
ATOM   544   N  NE1 . TRP A 1 72  ? 35.992  68.547  77.942  1.00 41.27  ? 72  TRP A NE1 1 
ATOM   545   C  CE2 . TRP A 1 72  ? 37.109  68.490  78.737  1.00 39.62  ? 72  TRP A CE2 1 
ATOM   546   C  CE3 . TRP A 1 72  ? 38.899  69.964  79.426  1.00 45.60  ? 72  TRP A CE3 1 
ATOM   547   C  CZ2 . TRP A 1 72  ? 37.631  67.435  79.482  1.00 44.84  ? 72  TRP A CZ2 1 
ATOM   548   C  CZ3 . TRP A 1 72  ? 39.420  68.916  80.160  1.00 48.92  ? 72  TRP A CZ3 1 
ATOM   549   C  CH2 . TRP A 1 72  ? 38.784  67.667  80.185  1.00 50.74  ? 72  TRP A CH2 1 
ATOM   550   N  N   . PRO A 1 73  ? 38.553  70.238  74.798  1.00 30.69  ? 73  PRO A N   1 
ATOM   551   C  CA  . PRO A 1 73  ? 38.181  69.534  73.567  1.00 37.16  ? 73  PRO A CA  1 
ATOM   552   C  C   . PRO A 1 73  ? 37.069  68.523  73.824  1.00 40.65  ? 73  PRO A C   1 
ATOM   553   O  O   . PRO A 1 73  ? 37.158  67.704  74.745  1.00 38.92  ? 73  PRO A O   1 
ATOM   554   C  CB  . PRO A 1 73  ? 39.481  68.838  73.153  1.00 31.64  ? 73  PRO A CB  1 
ATOM   555   C  CG  . PRO A 1 73  ? 40.178  68.591  74.442  1.00 34.29  ? 73  PRO A CG  1 
ATOM   556   C  CD  . PRO A 1 73  ? 39.763  69.675  75.414  1.00 33.90  ? 73  PRO A CD  1 
ATOM   557   N  N   . VAL A 1 74  ? 36.022  68.587  72.994  1.00 39.67  ? 74  VAL A N   1 
ATOM   558   C  CA  . VAL A 1 74  ? 34.867  67.688  73.032  1.00 35.90  ? 74  VAL A CA  1 
ATOM   559   C  C   . VAL A 1 74  ? 34.893  66.892  71.731  1.00 36.38  ? 74  VAL A C   1 
ATOM   560   O  O   . VAL A 1 74  ? 34.494  67.399  70.676  1.00 37.28  ? 74  VAL A O   1 
ATOM   561   C  CB  . VAL A 1 74  ? 33.551  68.464  73.185  1.00 41.37  ? 74  VAL A CB  1 
ATOM   562   C  CG1 . VAL A 1 74  ? 32.332  67.542  73.008  1.00 34.73  ? 74  VAL A CG1 1 
ATOM   563   C  CG2 . VAL A 1 74  ? 33.504  69.208  74.527  1.00 39.03  ? 74  VAL A CG2 1 
ATOM   564   N  N   . MET A 1 75  ? 35.356  65.646  71.785  1.00 34.48  ? 75  MET A N   1 
ATOM   565   C  CA  . MET A 1 75  ? 35.484  64.878  70.556  1.00 41.52  ? 75  MET A CA  1 
ATOM   566   C  C   . MET A 1 75  ? 35.506  63.388  70.878  1.00 38.55  ? 75  MET A C   1 
ATOM   567   O  O   . MET A 1 75  ? 35.947  62.976  71.954  1.00 41.67  ? 75  MET A O   1 
ATOM   568   C  CB  . MET A 1 75  ? 36.759  65.265  69.787  1.00 40.05  ? 75  MET A CB  1 
ATOM   569   C  CG  . MET A 1 75  ? 37.983  64.467  70.195  1.00 37.55  ? 75  MET A CG  1 
ATOM   570   S  SD  . MET A 1 75  ? 39.550  65.013  69.474  1.00 39.35  ? 75  MET A SD  1 
ATOM   571   C  CE  . MET A 1 75  ? 39.838  63.681  68.317  1.00 28.64  ? 75  MET A CE  1 
ATOM   572   N  N   . ARG A 1 76  ? 35.074  62.587  69.911  1.00 35.64  ? 76  ARG A N   1 
ATOM   573   C  CA  . ARG A 1 76  ? 35.074  61.136  70.028  1.00 41.79  ? 76  ARG A CA  1 
ATOM   574   C  C   . ARG A 1 76  ? 36.296  60.530  69.347  1.00 41.44  ? 76  ARG A C   1 
ATOM   575   O  O   . ARG A 1 76  ? 36.907  61.135  68.461  1.00 41.65  ? 76  ARG A O   1 
ATOM   576   C  CB  . ARG A 1 76  ? 33.798  60.562  69.416  1.00 43.84  ? 76  ARG A CB  1 
ATOM   577   C  CG  . ARG A 1 76  ? 32.534  61.069  70.099  1.00 42.84  ? 76  ARG A CG  1 
ATOM   578   C  CD  . ARG A 1 76  ? 31.302  60.749  69.285  1.00 48.32  ? 76  ARG A CD  1 
ATOM   579   N  NE  . ARG A 1 76  ? 31.004  61.796  68.316  1.00 53.48  ? 76  ARG A NE  1 
ATOM   580   C  CZ  . ARG A 1 76  ? 31.033  61.627  66.999  1.00 55.30  ? 76  ARG A CZ  1 
ATOM   581   N  NH1 . ARG A 1 76  ? 31.366  60.464  66.458  1.00 51.35  ? 76  ARG A NH1 1 
ATOM   582   N  NH2 . ARG A 1 76  ? 30.715  62.647  66.206  1.00 50.82  ? 76  ARG A NH2 1 
ATOM   583   N  N   . ILE A 1 77  ? 36.629  59.301  69.758  1.00 39.26  ? 77  ILE A N   1 
ATOM   584   C  CA  . ILE A 1 77  ? 37.816  58.622  69.234  1.00 40.64  ? 77  ILE A CA  1 
ATOM   585   C  C   . ILE A 1 77  ? 37.724  58.475  67.724  1.00 41.07  ? 77  ILE A C   1 
ATOM   586   O  O   . ILE A 1 77  ? 38.730  58.583  67.007  1.00 40.26  ? 77  ILE A O   1 
ATOM   587   C  CB  . ILE A 1 77  ? 38.009  57.250  69.920  1.00 42.42  ? 77  ILE A CB  1 
ATOM   588   C  CG1 . ILE A 1 77  ? 38.279  57.411  71.420  1.00 40.57  ? 77  ILE A CG1 1 
ATOM   589   C  CG2 . ILE A 1 77  ? 39.166  56.482  69.293  1.00 35.28  ? 77  ILE A CG2 1 
ATOM   590   C  CD1 . ILE A 1 77  ? 38.743  56.119  72.103  1.00 40.84  ? 77  ILE A CD1 1 
ATOM   591   N  N   . GLU A 1 78  ? 36.521  58.229  67.212  1.00 40.82  ? 78  GLU A N   1 
ATOM   592   C  CA  . GLU A 1 78  ? 36.367  58.009  65.782  1.00 40.19  ? 78  GLU A CA  1 
ATOM   593   C  C   . GLU A 1 78  ? 36.521  59.289  64.965  1.00 35.93  ? 78  GLU A C   1 
ATOM   594   O  O   . GLU A 1 78  ? 36.574  59.203  63.735  1.00 33.51  ? 78  GLU A O   1 
ATOM   595   C  CB  . GLU A 1 78  ? 35.004  57.379  65.493  1.00 40.75  ? 78  GLU A CB  1 
ATOM   596   C  CG  . GLU A 1 78  ? 33.869  58.382  65.549  1.00 44.03  ? 78  GLU A CG  1 
ATOM   597   C  CD  . GLU A 1 78  ? 32.510  57.733  65.690  1.00 53.19  ? 78  GLU A CD  1 
ATOM   598   O  OE1 . GLU A 1 78  ? 32.220  56.799  64.908  1.00 54.17  ? 78  GLU A OE1 1 
ATOM   599   O  OE2 . GLU A 1 78  ? 31.727  58.177  66.567  1.00 52.99  ? 78  GLU A OE2 1 
ATOM   600   N  N   . GLU A 1 79  ? 36.569  60.464  65.609  1.00 36.76  ? 79  GLU A N   1 
ATOM   601   C  CA  . GLU A 1 79  ? 36.863  61.707  64.904  1.00 35.49  ? 79  GLU A CA  1 
ATOM   602   C  C   . GLU A 1 79  ? 38.360  61.956  64.731  1.00 34.88  ? 79  GLU A C   1 
ATOM   603   O  O   . GLU A 1 79  ? 38.738  62.877  63.991  1.00 34.77  ? 79  GLU A O   1 
ATOM   604   C  CB  . GLU A 1 79  ? 36.224  62.885  65.633  1.00 37.22  ? 79  GLU A CB  1 
ATOM   605   C  CG  . GLU A 1 79  ? 34.744  62.716  65.937  1.00 40.34  ? 79  GLU A CG  1 
ATOM   606   C  CD  . GLU A 1 79  ? 34.133  63.964  66.536  1.00 37.44  ? 79  GLU A CD  1 
ATOM   607   O  OE1 . GLU A 1 79  ? 33.768  64.865  65.764  1.00 38.06  ? 79  GLU A OE1 1 
ATOM   608   O  OE2 . GLU A 1 79  ? 34.031  64.051  67.777  1.00 39.39  ? 79  GLU A OE2 1 
ATOM   609   N  N   . GLY A 1 80  ? 39.213  61.176  65.399  1.00 34.17  ? 80  GLY A N   1 
ATOM   610   C  CA  . GLY A 1 80  ? 40.636  61.218  65.155  1.00 31.52  ? 80  GLY A CA  1 
ATOM   611   C  C   . GLY A 1 80  ? 40.926  61.114  63.672  1.00 33.41  ? 80  GLY A C   1 
ATOM   612   O  O   . GLY A 1 80  ? 40.250  60.368  62.959  1.00 31.82  ? 80  GLY A O   1 
ATOM   613   N  N   . CYS A 1 81  ? 41.908  61.868  63.179  1.00 29.60  ? 81  CYS A N   1 
ATOM   614   C  CA  . CYS A 1 81  ? 42.087  61.923  61.733  1.00 31.40  ? 81  CYS A CA  1 
ATOM   615   C  C   . CYS A 1 81  ? 42.429  60.546  61.167  1.00 31.64  ? 81  CYS A C   1 
ATOM   616   O  O   . CYS A 1 81  ? 41.864  60.142  60.143  1.00 35.05  ? 81  CYS A O   1 
ATOM   617   C  CB  . CYS A 1 81  ? 43.135  62.976  61.356  1.00 23.89  ? 81  CYS A CB  1 
ATOM   618   S  SG  . CYS A 1 81  ? 44.795  62.673  61.916  1.00 31.24  ? 81  CYS A SG  1 
ATOM   619   N  N   . VAL A 1 82  ? 43.321  59.793  61.826  1.00 26.52  ? 82  VAL A N   1 
ATOM   620   C  CA  . VAL A 1 82  ? 43.634  58.450  61.326  1.00 31.24  ? 82  VAL A CA  1 
ATOM   621   C  C   . VAL A 1 82  ? 42.373  57.595  61.277  1.00 34.75  ? 82  VAL A C   1 
ATOM   622   O  O   . VAL A 1 82  ? 42.105  56.901  60.290  1.00 32.58  ? 82  VAL A O   1 
ATOM   623   C  CB  . VAL A 1 82  ? 44.710  57.763  62.180  1.00 30.75  ? 82  VAL A CB  1 
ATOM   624   C  CG1 . VAL A 1 82  ? 44.765  56.279  61.804  1.00 29.83  ? 82  VAL A CG1 1 
ATOM   625   C  CG2 . VAL A 1 82  ? 46.073  58.439  62.007  1.00 29.88  ? 82  VAL A CG2 1 
ATOM   626   N  N   . GLN A 1 83  ? 41.590  57.627  62.357  1.00 33.31  ? 83  GLN A N   1 
ATOM   627   C  CA  . GLN A 1 83  ? 40.362  56.847  62.440  1.00 33.59  ? 83  GLN A CA  1 
ATOM   628   C  C   . GLN A 1 83  ? 39.363  57.269  61.367  1.00 36.93  ? 83  GLN A C   1 
ATOM   629   O  O   . GLN A 1 83  ? 38.911  56.447  60.563  1.00 35.75  ? 83  GLN A O   1 
ATOM   630   C  CB  . GLN A 1 83  ? 39.766  57.008  63.838  1.00 34.76  ? 83  GLN A CB  1 
ATOM   631   C  CG  . GLN A 1 83  ? 40.609  56.381  64.948  1.00 35.67  ? 83  GLN A CG  1 
ATOM   632   C  CD  . GLN A 1 83  ? 41.909  57.130  65.272  1.00 37.37  ? 83  GLN A CD  1 
ATOM   633   O  OE1 . GLN A 1 83  ? 42.023  58.356  65.103  1.00 34.53  ? 83  GLN A OE1 1 
ATOM   634   N  NE2 . GLN A 1 83  ? 42.895  56.382  65.750  1.00 30.85  ? 83  GLN A NE2 1 
ATOM   635   N  N   . ALA A 1 84  ? 39.024  58.564  61.325  1.00 36.79  ? 84  ALA A N   1 
ATOM   636   C  CA  . ALA A 1 84  ? 38.077  59.043  60.323  1.00 36.51  ? 84  ALA A CA  1 
ATOM   637   C  C   . ALA A 1 84  ? 38.488  58.622  58.918  1.00 36.20  ? 84  ALA A C   1 
ATOM   638   O  O   . ALA A 1 84  ? 37.639  58.245  58.104  1.00 40.02  ? 84  ALA A O   1 
ATOM   639   C  CB  . ALA A 1 84  ? 37.940  60.558  60.406  1.00 33.25  ? 84  ALA A CB  1 
ATOM   640   N  N   . LEU A 1 85  ? 39.790  58.634  58.629  1.00 35.97  ? 85  LEU A N   1 
ATOM   641   C  CA  . LEU A 1 85  ? 40.244  58.291  57.283  1.00 38.09  ? 85  LEU A CA  1 
ATOM   642   C  C   . LEU A 1 85  ? 40.096  56.797  57.006  1.00 40.04  ? 85  LEU A C   1 
ATOM   643   O  O   . LEU A 1 85  ? 39.670  56.402  55.912  1.00 37.92  ? 85  LEU A O   1 
ATOM   644   C  CB  . LEU A 1 85  ? 41.700  58.724  57.086  1.00 36.47  ? 85  LEU A CB  1 
ATOM   645   C  CG  . LEU A 1 85  ? 41.989  60.208  56.830  1.00 41.60  ? 85  LEU A CG  1 
ATOM   646   C  CD1 . LEU A 1 85  ? 43.402  60.372  56.288  1.00 33.64  ? 85  LEU A CD1 1 
ATOM   647   C  CD2 . LEU A 1 85  ? 40.960  60.824  55.876  1.00 38.88  ? 85  LEU A CD2 1 
ATOM   648   N  N   . LYS A 1 86  ? 40.473  55.953  57.971  1.00 40.69  ? 86  LYS A N   1 
ATOM   649   C  CA  . LYS A 1 86  ? 40.314  54.510  57.799  1.00 44.38  ? 86  LYS A CA  1 
ATOM   650   C  C   . LYS A 1 86  ? 38.889  54.168  57.388  1.00 42.98  ? 86  LYS A C   1 
ATOM   651   O  O   . LYS A 1 86  ? 38.666  53.509  56.369  1.00 42.32  ? 86  LYS A O   1 
ATOM   652   C  CB  . LYS A 1 86  ? 40.692  53.779  59.087  1.00 41.16  ? 86  LYS A CB  1 
ATOM   653   C  CG  . LYS A 1 86  ? 42.160  53.437  59.167  1.00 44.66  ? 86  LYS A CG  1 
ATOM   654   C  CD  . LYS A 1 86  ? 42.436  52.471  60.300  1.00 51.55  ? 86  LYS A CD  1 
ATOM   655   C  CE  . LYS A 1 86  ? 42.265  51.025  59.857  1.00 50.58  ? 86  LYS A CE  1 
ATOM   656   N  NZ  . LYS A 1 86  ? 43.590  50.413  59.565  1.00 51.88  ? 86  LYS A NZ  1 
ATOM   657   N  N   . ALA A 1 87  ? 37.912  54.654  58.158  1.00 41.69  ? 87  ALA A N   1 
ATOM   658   C  CA  . ALA A 1 87  ? 36.510  54.453  57.820  1.00 39.52  ? 87  ALA A CA  1 
ATOM   659   C  C   . ALA A 1 87  ? 36.185  54.992  56.434  1.00 42.58  ? 87  ALA A C   1 
ATOM   660   O  O   . ALA A 1 87  ? 35.386  54.397  55.703  1.00 46.98  ? 87  ALA A O   1 
ATOM   661   C  CB  . ALA A 1 87  ? 35.626  55.116  58.878  1.00 37.83  ? 87  ALA A CB  1 
ATOM   662   N  N   . PHE A 1 88  ? 36.786  56.118  56.050  1.00 44.91  ? 88  PHE A N   1 
ATOM   663   C  CA  . PHE A 1 88  ? 36.536  56.653  54.714  1.00 41.14  ? 88  PHE A CA  1 
ATOM   664   C  C   . PHE A 1 88  ? 37.179  55.794  53.631  1.00 38.02  ? 88  PHE A C   1 
ATOM   665   O  O   . PHE A 1 88  ? 36.820  55.914  52.459  1.00 37.35  ? 88  PHE A O   1 
ATOM   666   C  CB  . PHE A 1 88  ? 37.040  58.107  54.631  1.00 44.51  ? 88  PHE A CB  1 
ATOM   667   C  CG  . PHE A 1 88  ? 36.959  58.715  53.245  1.00 45.35  ? 88  PHE A CG  1 
ATOM   668   C  CD1 . PHE A 1 88  ? 35.781  59.305  52.797  1.00 46.40  ? 88  PHE A CD1 1 
ATOM   669   C  CD2 . PHE A 1 88  ? 38.059  58.699  52.395  1.00 45.27  ? 88  PHE A CD2 1 
ATOM   670   C  CE1 . PHE A 1 88  ? 35.694  59.856  51.527  1.00 43.56  ? 88  PHE A CE1 1 
ATOM   671   C  CE2 . PHE A 1 88  ? 37.980  59.250  51.114  1.00 44.98  ? 88  PHE A CE2 1 
ATOM   672   C  CZ  . PHE A 1 88  ? 36.797  59.833  50.685  1.00 41.04  ? 88  PHE A CZ  1 
ATOM   673   N  N   . GLY A 1 89  ? 38.124  54.935  53.987  1.00 39.30  ? 89  GLY A N   1 
ATOM   674   C  CA  . GLY A 1 89  ? 38.750  54.059  53.026  1.00 37.93  ? 89  GLY A CA  1 
ATOM   675   C  C   . GLY A 1 89  ? 40.194  54.368  52.700  1.00 42.16  ? 89  GLY A C   1 
ATOM   676   O  O   . GLY A 1 89  ? 40.718  53.818  51.716  1.00 33.96  ? 89  GLY A O   1 
ATOM   677   N  N   . ILE A 1 90  ? 40.854  55.227  53.478  1.00 39.00  ? 90  ILE A N   1 
ATOM   678   C  CA  . ILE A 1 90  ? 42.251  55.596  53.249  1.00 36.87  ? 90  ILE A CA  1 
ATOM   679   C  C   . ILE A 1 90  ? 43.066  55.128  54.445  1.00 35.88  ? 90  ILE A C   1 
ATOM   680   O  O   . ILE A 1 90  ? 42.826  55.559  55.579  1.00 40.80  ? 90  ILE A O   1 
ATOM   681   C  CB  . ILE A 1 90  ? 42.420  57.109  53.026  1.00 38.71  ? 90  ILE A CB  1 
ATOM   682   C  CG1 . ILE A 1 90  ? 41.810  57.532  51.694  1.00 37.80  ? 90  ILE A CG1 1 
ATOM   683   C  CG2 . ILE A 1 90  ? 43.892  57.505  53.073  1.00 35.46  ? 90  ILE A CG2 1 
ATOM   684   C  CD1 . ILE A 1 90  ? 41.538  59.017  51.603  1.00 33.70  ? 90  ILE A CD1 1 
ATOM   685   N  N   . GLU A 1 91  ? 44.017  54.253  54.198  1.00 33.65  ? 91  GLU A N   1 
ATOM   686   C  CA  . GLU A 1 91  ? 44.883  53.746  55.245  1.00 40.44  ? 91  GLU A CA  1 
ATOM   687   C  C   . GLU A 1 91  ? 46.006  54.744  55.542  1.00 40.03  ? 91  GLU A C   1 
ATOM   688   O  O   . GLU A 1 91  ? 46.432  55.486  54.655  1.00 37.09  ? 91  GLU A O   1 
ATOM   689   C  CB  . GLU A 1 91  ? 45.476  52.398  54.827  1.00 42.15  ? 91  GLU A CB  1 
ATOM   690   C  CG  . GLU A 1 91  ? 44.446  51.262  54.784  1.00 44.90  ? 91  GLU A CG  1 
ATOM   691   C  CD  . GLU A 1 91  ? 43.886  50.950  56.162  1.00 48.43  ? 91  GLU A CD  1 
ATOM   692   O  OE1 . GLU A 1 91  ? 44.687  50.680  57.080  1.00 49.76  ? 91  GLU A OE1 1 
ATOM   693   O  OE2 . GLU A 1 91  ? 42.647  50.987  56.333  1.00 50.67  ? 91  GLU A OE2 1 
ATOM   694   N  N   . PRO A 1 92  ? 46.502  54.768  56.783  1.00 38.44  ? 92  PRO A N   1 
ATOM   695   C  CA  . PRO A 1 92  ? 47.535  55.751  57.151  1.00 34.87  ? 92  PRO A CA  1 
ATOM   696   C  C   . PRO A 1 92  ? 48.708  55.786  56.202  1.00 36.92  ? 92  PRO A C   1 
ATOM   697   O  O   . PRO A 1 92  ? 49.313  56.850  56.005  1.00 35.86  ? 92  PRO A O   1 
ATOM   698   C  CB  . PRO A 1 92  ? 47.973  55.278  58.541  1.00 41.26  ? 92  PRO A CB  1 
ATOM   699   C  CG  . PRO A 1 92  ? 46.780  54.550  59.084  1.00 43.65  ? 92  PRO A CG  1 
ATOM   700   C  CD  . PRO A 1 92  ? 46.132  53.893  57.912  1.00 38.38  ? 92  PRO A CD  1 
ATOM   701   N  N   . ALA A 1 93  ? 49.054  54.647  55.605  1.00 35.72  ? 93  ALA A N   1 
ATOM   702   C  CA  . ALA A 1 93  ? 50.165  54.601  54.670  1.00 35.04  ? 93  ALA A CA  1 
ATOM   703   C  C   . ALA A 1 93  ? 49.838  55.288  53.349  1.00 36.72  ? 93  ALA A C   1 
ATOM   704   O  O   . ALA A 1 93  ? 50.758  55.615  52.595  1.00 28.22  ? 93  ALA A O   1 
ATOM   705   C  CB  . ALA A 1 93  ? 50.577  53.145  54.418  1.00 34.89  ? 93  ALA A CB  1 
ATOM   706   N  N   . ASP A 1 94  ? 48.558  55.513  53.053  1.00 36.04  ? 94  ASP A N   1 
ATOM   707   C  CA  . ASP A 1 94  ? 48.149  56.099  51.775  1.00 39.10  ? 94  ASP A CA  1 
ATOM   708   C  C   . ASP A 1 94  ? 48.003  57.615  51.858  1.00 35.91  ? 94  ASP A C   1 
ATOM   709   O  O   . ASP A 1 94  ? 47.080  58.176  51.263  1.00 36.66  ? 94  ASP A O   1 
ATOM   710   C  CB  . ASP A 1 94  ? 46.846  55.460  51.287  1.00 37.37  ? 94  ASP A CB  1 
ATOM   711   C  CG  . ASP A 1 94  ? 46.940  53.930  51.142  1.00 56.10  ? 94  ASP A CG  1 
ATOM   712   O  OD1 . ASP A 1 94  ? 48.035  53.414  50.812  1.00 54.40  ? 94  ASP A OD1 1 
ATOM   713   O  OD2 . ASP A 1 94  ? 45.904  53.241  51.353  1.00 59.43  ? 94  ASP A OD2 1 
ATOM   714   N  N   . VAL A 1 95  ? 48.867  58.300  52.603  1.00 35.01  ? 95  VAL A N   1 
ATOM   715   C  CA  . VAL A 1 95  ? 48.865  59.759  52.683  1.00 28.47  ? 95  VAL A CA  1 
ATOM   716   C  C   . VAL A 1 95  ? 50.250  60.229  52.286  1.00 29.43  ? 95  VAL A C   1 
ATOM   717   O  O   . VAL A 1 95  ? 51.240  59.854  52.920  1.00 29.43  ? 95  VAL A O   1 
ATOM   718   C  CB  . VAL A 1 95  ? 48.503  60.264  54.084  1.00 26.97  ? 95  VAL A CB  1 
ATOM   719   C  CG1 . VAL A 1 95  ? 48.693  61.771  54.168  1.00 30.19  ? 95  VAL A CG1 1 
ATOM   720   C  CG2 . VAL A 1 95  ? 47.072  59.888  54.443  1.00 28.32  ? 95  VAL A CG2 1 
ATOM   721   N  N   . ARG A 1 96  ? 50.327  61.029  51.228  1.00 27.98  ? 96  ARG A N   1 
ATOM   722   C  CA  . ARG A 1 96  ? 51.624  61.458  50.724  1.00 30.54  ? 96  ARG A CA  1 
ATOM   723   C  C   . ARG A 1 96  ? 52.123  62.716  51.426  1.00 26.58  ? 96  ARG A C   1 
ATOM   724   O  O   . ARG A 1 96  ? 53.321  62.851  51.662  1.00 27.67  ? 96  ARG A O   1 
ATOM   725   C  CB  . ARG A 1 96  ? 51.551  61.707  49.219  1.00 26.76  ? 96  ARG A CB  1 
ATOM   726   C  CG  . ARG A 1 96  ? 52.923  61.937  48.586  1.00 28.30  ? 96  ARG A CG  1 
ATOM   727   C  CD  . ARG A 1 96  ? 52.775  62.273  47.106  1.00 25.68  ? 96  ARG A CD  1 
ATOM   728   N  NE  . ARG A 1 96  ? 54.046  62.628  46.491  1.00 31.51  ? 96  ARG A NE  1 
ATOM   729   C  CZ  . ARG A 1 96  ? 54.220  62.766  45.186  1.00 33.30  ? 96  ARG A CZ  1 
ATOM   730   N  NH1 . ARG A 1 96  ? 53.234  62.537  44.332  1.00 35.26  ? 96  ARG A NH1 1 
ATOM   731   N  NH2 . ARG A 1 96  ? 55.413  63.125  44.725  1.00 24.81  ? 96  ARG A NH2 1 
ATOM   732   N  N   . TYR A 1 97  ? 51.224  63.627  51.785  1.00 28.06  ? 97  TYR A N   1 
ATOM   733   C  CA  . TYR A 1 97  ? 51.608  64.900  52.373  1.00 25.58  ? 97  TYR A CA  1 
ATOM   734   C  C   . TYR A 1 97  ? 50.722  65.210  53.563  1.00 26.13  ? 97  TYR A C   1 
ATOM   735   O  O   . TYR A 1 97  ? 49.497  65.056  53.493  1.00 24.81  ? 97  TYR A O   1 
ATOM   736   C  CB  . TYR A 1 97  ? 51.478  66.057  51.375  1.00 23.02  ? 97  TYR A CB  1 
ATOM   737   C  CG  . TYR A 1 97  ? 52.423  65.969  50.215  1.00 24.59  ? 97  TYR A CG  1 
ATOM   738   C  CD1 . TYR A 1 97  ? 53.800  66.025  50.416  1.00 26.16  ? 97  TYR A CD1 1 
ATOM   739   C  CD2 . TYR A 1 97  ? 51.949  65.829  48.912  1.00 26.14  ? 97  TYR A CD2 1 
ATOM   740   C  CE1 . TYR A 1 97  ? 54.677  65.943  49.348  1.00 26.25  ? 97  TYR A CE1 1 
ATOM   741   C  CE2 . TYR A 1 97  ? 52.825  65.759  47.841  1.00 25.00  ? 97  TYR A CE2 1 
ATOM   742   C  CZ  . TYR A 1 97  ? 54.179  65.805  48.067  1.00 24.29  ? 97  TYR A CZ  1 
ATOM   743   O  OH  . TYR A 1 97  ? 55.055  65.739  47.012  1.00 26.86  ? 97  TYR A OH  1 
ATOM   744   N  N   . VAL A 1 98  ? 51.348  65.687  54.634  1.00 25.67  ? 98  VAL A N   1 
ATOM   745   C  CA  . VAL A 1 98  ? 50.655  66.418  55.687  1.00 26.09  ? 98  VAL A CA  1 
ATOM   746   C  C   . VAL A 1 98  ? 51.075  67.887  55.591  1.00 24.12  ? 98  VAL A C   1 
ATOM   747   O  O   . VAL A 1 98  ? 52.265  68.211  55.673  1.00 23.47  ? 98  VAL A O   1 
ATOM   748   C  CB  . VAL A 1 98  ? 50.956  65.847  57.079  1.00 23.49  ? 98  VAL A CB  1 
ATOM   749   C  CG1 . VAL A 1 98  ? 50.365  66.767  58.146  1.00 22.43  ? 98  VAL A CG1 1 
ATOM   750   C  CG2 . VAL A 1 98  ? 50.393  64.448  57.195  1.00 25.16  ? 98  VAL A CG2 1 
ATOM   751   N  N   . LEU A 1 99  ? 50.100  68.765  55.440  1.00 22.17  ? 99  LEU A N   1 
ATOM   752   C  CA  . LEU A 1 99  ? 50.313  70.203  55.384  1.00 23.22  ? 99  LEU A CA  1 
ATOM   753   C  C   . LEU A 1 99  ? 49.922  70.813  56.724  1.00 22.30  ? 99  LEU A C   1 
ATOM   754   O  O   . LEU A 1 99  ? 48.920  70.415  57.319  1.00 23.99  ? 99  LEU A O   1 
ATOM   755   C  CB  . LEU A 1 99  ? 49.471  70.807  54.265  1.00 21.54  ? 99  LEU A CB  1 
ATOM   756   C  CG  . LEU A 1 99  ? 50.056  70.851  52.851  1.00 24.50  ? 99  LEU A CG  1 
ATOM   757   C  CD1 . LEU A 1 99  ? 50.742  69.580  52.472  1.00 22.65  ? 99  LEU A CD1 1 
ATOM   758   C  CD2 . LEU A 1 99  ? 48.971  71.195  51.821  1.00 21.56  ? 99  LEU A CD2 1 
ATOM   759   N  N   . HIS A 1 100 ? 50.708  71.768  57.215  1.00 21.50  ? 100 HIS A N   1 
ATOM   760   C  CA  . HIS A 1 100 ? 50.361  72.438  58.468  1.00 23.47  ? 100 HIS A CA  1 
ATOM   761   C  C   . HIS A 1 100 ? 50.215  73.938  58.256  1.00 21.74  ? 100 HIS A C   1 
ATOM   762   O  O   . HIS A 1 100 ? 51.160  74.615  57.834  1.00 23.96  ? 100 HIS A O   1 
ATOM   763   C  CB  . HIS A 1 100 ? 51.374  72.139  59.575  1.00 19.74  ? 100 HIS A CB  1 
ATOM   764   C  CG  . HIS A 1 100 ? 51.122  70.832  60.266  1.00 20.63  ? 100 HIS A CG  1 
ATOM   765   N  ND1 . HIS A 1 100 ? 49.988  70.589  61.011  1.00 19.50  ? 100 HIS A ND1 1 
ATOM   766   C  CD2 . HIS A 1 100 ? 51.851  69.692  60.306  1.00 20.53  ? 100 HIS A CD2 1 
ATOM   767   C  CE1 . HIS A 1 100 ? 50.027  69.352  61.474  1.00 22.31  ? 100 HIS A CE1 1 
ATOM   768   N  NE2 . HIS A 1 100 ? 51.154  68.791  61.071  1.00 23.42  ? 100 HIS A NE2 1 
ATOM   769   N  N   . SER A 1 101 ? 49.011  74.439  58.524  1.00 20.96  ? 101 SER A N   1 
ATOM   770   C  CA  . SER A 1 101 ? 48.785  75.871  58.633  1.00 19.15  ? 101 SER A CA  1 
ATOM   771   C  C   . SER A 1 101 ? 49.673  76.473  59.707  1.00 20.82  ? 101 SER A C   1 
ATOM   772   O  O   . SER A 1 101 ? 50.276  77.540  59.513  1.00 21.93  ? 101 SER A O   1 
ATOM   773   C  CB  . SER A 1 101 ? 47.308  76.127  58.955  1.00 22.04  ? 101 SER A CB  1 
ATOM   774   O  OG  . SER A 1 101 ? 46.970  75.640  60.265  1.00 23.30  ? 101 SER A OG  1 
ATOM   775   N  N   . HIS A 1 102 ? 49.734  75.814  60.860  1.00 20.26  ? 102 HIS A N   1 
ATOM   776   C  CA  . HIS A 1 102 ? 50.577  76.192  61.995  1.00 19.95  ? 102 HIS A CA  1 
ATOM   777   C  C   . HIS A 1 102 ? 50.576  75.003  62.953  1.00 22.21  ? 102 HIS A C   1 
ATOM   778   O  O   . HIS A 1 102 ? 49.968  73.964  62.676  1.00 21.53  ? 102 HIS A O   1 
ATOM   779   C  CB  . HIS A 1 102 ? 50.121  77.499  62.656  1.00 18.44  ? 102 HIS A CB  1 
ATOM   780   C  CG  . HIS A 1 102 ? 48.715  77.486  63.193  1.00 22.22  ? 102 HIS A CG  1 
ATOM   781   N  ND1 . HIS A 1 102 ? 47.643  76.962  62.496  1.00 24.12  ? 102 HIS A ND1 1 
ATOM   782   C  CD2 . HIS A 1 102 ? 48.204  77.987  64.346  1.00 21.10  ? 102 HIS A CD2 1 
ATOM   783   C  CE1 . HIS A 1 102 ? 46.534  77.147  63.194  1.00 23.85  ? 102 HIS A CE1 1 
ATOM   784   N  NE2 . HIS A 1 102 ? 46.850  77.755  64.325  1.00 26.41  ? 102 HIS A NE2 1 
ATOM   785   N  N   . LEU A 1 103 ? 51.283  75.136  64.073  1.00 21.65  ? 103 LEU A N   1 
ATOM   786   C  CA  . LEU A 1 103 ? 51.493  73.981  64.939  1.00 18.38  ? 103 LEU A CA  1 
ATOM   787   C  C   . LEU A 1 103 ? 50.768  74.106  66.287  1.00 22.00  ? 103 LEU A C   1 
ATOM   788   O  O   . LEU A 1 103 ? 51.147  73.448  67.262  1.00 24.05  ? 103 LEU A O   1 
ATOM   789   C  CB  . LEU A 1 103 ? 52.988  73.747  65.123  1.00 16.35  ? 103 LEU A CB  1 
ATOM   790   C  CG  . LEU A 1 103 ? 53.646  73.290  63.808  1.00 21.35  ? 103 LEU A CG  1 
ATOM   791   C  CD1 . LEU A 1 103 ? 55.183  73.204  63.910  1.00 17.29  ? 103 LEU A CD1 1 
ATOM   792   C  CD2 . LEU A 1 103 ? 53.047  71.956  63.324  1.00 14.54  ? 103 LEU A CD2 1 
ATOM   793   N  N   . HIS A 1 104 ? 49.710  74.906  66.345  1.00 21.59  ? 104 HIS A N   1 
ATOM   794   C  CA  . HIS A 1 104 ? 48.890  74.968  67.540  1.00 24.70  ? 104 HIS A CA  1 
ATOM   795   C  C   . HIS A 1 104 ? 48.222  73.617  67.794  1.00 26.92  ? 104 HIS A C   1 
ATOM   796   O  O   . HIS A 1 104 ? 48.141  72.752  66.910  1.00 24.71  ? 104 HIS A O   1 
ATOM   797   C  CB  . HIS A 1 104 ? 47.846  76.074  67.398  1.00 25.00  ? 104 HIS A CB  1 
ATOM   798   C  CG  . HIS A 1 104 ? 48.402  77.444  67.626  1.00 26.03  ? 104 HIS A CG  1 
ATOM   799   N  ND1 . HIS A 1 104 ? 47.650  78.589  67.483  1.00 24.18  ? 104 HIS A ND1 1 
ATOM   800   C  CD2 . HIS A 1 104 ? 49.640  77.851  67.996  1.00 23.80  ? 104 HIS A CD2 1 
ATOM   801   C  CE1 . HIS A 1 104 ? 48.399  79.645  67.744  1.00 26.16  ? 104 HIS A CE1 1 
ATOM   802   N  NE2 . HIS A 1 104 ? 49.611  79.225  68.059  1.00 27.50  ? 104 HIS A NE2 1 
ATOM   803   N  N   . LEU A 1 105 ? 47.720  73.465  69.021  1.00 24.40  ? 105 LEU A N   1 
ATOM   804   C  CA  . LEU A 1 105 ? 47.291  72.168  69.552  1.00 26.96  ? 105 LEU A CA  1 
ATOM   805   C  C   . LEU A 1 105 ? 46.072  71.590  68.833  1.00 27.96  ? 105 LEU A C   1 
ATOM   806   O  O   . LEU A 1 105 ? 45.896  70.368  68.818  1.00 29.58  ? 105 LEU A O   1 
ATOM   807   C  CB  . LEU A 1 105 ? 46.999  72.288  71.048  1.00 27.45  ? 105 LEU A CB  1 
ATOM   808   C  CG  . LEU A 1 105 ? 45.705  72.996  71.476  1.00 29.82  ? 105 LEU A CG  1 
ATOM   809   C  CD1 . LEU A 1 105 ? 45.567  72.915  72.976  1.00 31.89  ? 105 LEU A CD1 1 
ATOM   810   C  CD2 . LEU A 1 105 ? 45.675  74.454  71.038  1.00 27.44  ? 105 LEU A CD2 1 
ATOM   811   N  N   . ASP A 1 106 ? 45.219  72.416  68.234  1.00 27.30  ? 106 ASP A N   1 
ATOM   812   C  CA  . ASP A 1 106 ? 44.092  71.878  67.479  1.00 25.19  ? 106 ASP A CA  1 
ATOM   813   C  C   . ASP A 1 106 ? 44.402  71.748  65.992  1.00 26.53  ? 106 ASP A C   1 
ATOM   814   O  O   . ASP A 1 106 ? 43.481  71.631  65.172  1.00 25.56  ? 106 ASP A O   1 
ATOM   815   C  CB  . ASP A 1 106 ? 42.845  72.729  67.716  1.00 24.65  ? 106 ASP A CB  1 
ATOM   816   C  CG  . ASP A 1 106 ? 43.102  74.221  67.513  1.00 31.27  ? 106 ASP A CG  1 
ATOM   817   O  OD1 . ASP A 1 106 ? 44.148  74.754  67.971  1.00 27.43  ? 106 ASP A OD1 1 
ATOM   818   O  OD2 . ASP A 1 106 ? 42.235  74.865  66.908  1.00 26.18  ? 106 ASP A OD2 1 
ATOM   819   N  N   . HIS A 1 107 ? 45.693  71.726  65.630  1.00 25.09  ? 107 HIS A N   1 
ATOM   820   C  CA  . HIS A 1 107 ? 46.082  71.564  64.238  1.00 22.16  ? 107 HIS A CA  1 
ATOM   821   C  C   . HIS A 1 107 ? 47.231  70.582  64.062  1.00 24.65  ? 107 HIS A C   1 
ATOM   822   O  O   . HIS A 1 107 ? 47.802  70.521  62.962  1.00 25.97  ? 107 HIS A O   1 
ATOM   823   C  CB  . HIS A 1 107 ? 46.462  72.935  63.617  1.00 25.33  ? 107 HIS A CB  1 
ATOM   824   C  CG  . HIS A 1 107 ? 45.326  73.910  63.591  1.00 20.88  ? 107 HIS A CG  1 
ATOM   825   N  ND1 . HIS A 1 107 ? 44.463  74.020  62.524  1.00 19.89  ? 107 HIS A ND1 1 
ATOM   826   C  CD2 . HIS A 1 107 ? 44.896  74.805  64.516  1.00 26.82  ? 107 HIS A CD2 1 
ATOM   827   C  CE1 . HIS A 1 107 ? 43.548  74.937  62.791  1.00 24.78  ? 107 HIS A CE1 1 
ATOM   828   N  NE2 . HIS A 1 107 ? 43.785  75.428  63.995  1.00 24.87  ? 107 HIS A NE2 1 
ATOM   829   N  N   . THR A 1 108 ? 47.604  69.826  65.101  1.00 22.23  ? 108 THR A N   1 
ATOM   830   C  CA  . THR A 1 108 ? 48.731  68.901  65.022  1.00 24.47  ? 108 THR A CA  1 
ATOM   831   C  C   . THR A 1 108 ? 48.320  67.446  65.250  1.00 23.89  ? 108 THR A C   1 
ATOM   832   O  O   . THR A 1 108 ? 49.188  66.595  65.480  1.00 26.55  ? 108 THR A O   1 
ATOM   833   C  CB  . THR A 1 108 ? 49.831  69.299  66.015  1.00 21.79  ? 108 THR A CB  1 
ATOM   834   O  OG1 . THR A 1 108 ? 49.258  69.629  67.283  1.00 24.47  ? 108 THR A OG1 1 
ATOM   835   C  CG2 . THR A 1 108 ? 50.592  70.524  65.505  1.00 22.25  ? 108 THR A CG2 1 
ATOM   836   N  N   . GLY A 1 109 ? 47.022  67.137  65.173  1.00 28.98  ? 109 GLY A N   1 
ATOM   837   C  CA  . GLY A 1 109 ? 46.581  65.753  65.318  1.00 28.19  ? 109 GLY A CA  1 
ATOM   838   C  C   . GLY A 1 109 ? 47.125  64.832  64.241  1.00 27.53  ? 109 GLY A C   1 
ATOM   839   O  O   . GLY A 1 109 ? 47.258  63.629  64.449  1.00 28.35  ? 109 GLY A O   1 
ATOM   840   N  N   . ALA A 1 110 ? 47.455  65.372  63.078  1.00 26.66  ? 110 ALA A N   1 
ATOM   841   C  CA  . ALA A 1 110 ? 47.978  64.517  62.027  1.00 26.67  ? 110 ALA A CA  1 
ATOM   842   C  C   . ALA A 1 110 ? 49.464  64.251  62.177  1.00 24.33  ? 110 ALA A C   1 
ATOM   843   O  O   . ALA A 1 110 ? 49.950  63.270  61.615  1.00 26.37  ? 110 ALA A O   1 
ATOM   844   C  CB  . ALA A 1 110 ? 47.711  65.141  60.652  1.00 25.11  ? 110 ALA A CB  1 
ATOM   845   N  N   . THR A 1 111 ? 50.196  65.094  62.902  1.00 25.49  ? 111 THR A N   1 
ATOM   846   C  CA  . THR A 1 111 ? 51.652  65.052  62.808  1.00 24.86  ? 111 THR A CA  1 
ATOM   847   C  C   . THR A 1 111 ? 52.207  63.701  63.260  1.00 29.36  ? 111 THR A C   1 
ATOM   848   O  O   . THR A 1 111 ? 51.951  63.244  64.383  1.00 24.73  ? 111 THR A O   1 
ATOM   849   C  CB  . THR A 1 111 ? 52.294  66.177  63.633  1.00 24.01  ? 111 THR A CB  1 
ATOM   850   O  OG1 . THR A 1 111 ? 51.636  67.428  63.386  1.00 23.52  ? 111 THR A OG1 1 
ATOM   851   C  CG2 . THR A 1 111 ? 53.784  66.302  63.245  1.00 21.73  ? 111 THR A CG2 1 
ATOM   852   N  N   . GLY A 1 112 ? 53.008  63.085  62.390  1.00 24.65  ? 112 GLY A N   1 
ATOM   853   C  CA  . GLY A 1 112 ? 53.619  61.802  62.690  1.00 30.98  ? 112 GLY A CA  1 
ATOM   854   C  C   . GLY A 1 112 ? 52.699  60.602  62.563  1.00 30.23  ? 112 GLY A C   1 
ATOM   855   O  O   . GLY A 1 112 ? 53.159  59.467  62.729  1.00 30.47  ? 112 GLY A O   1 
ATOM   856   N  N   . ARG A 1 113 ? 51.425  60.807  62.260  1.00 26.90  ? 113 ARG A N   1 
ATOM   857   C  CA  . ARG A 1 113 ? 50.471  59.711  62.215  1.00 27.19  ? 113 ARG A CA  1 
ATOM   858   C  C   . ARG A 1 113 ? 50.425  59.044  60.854  1.00 29.77  ? 113 ARG A C   1 
ATOM   859   O  O   . ARG A 1 113 ? 49.803  57.989  60.709  1.00 32.12  ? 113 ARG A O   1 
ATOM   860   C  CB  . ARG A 1 113 ? 49.076  60.212  62.594  1.00 23.16  ? 113 ARG A CB  1 
ATOM   861   C  CG  . ARG A 1 113 ? 48.786  60.238  64.072  1.00 27.16  ? 113 ARG A CG  1 
ATOM   862   C  CD  . ARG A 1 113 ? 49.657  61.241  64.787  1.00 27.42  ? 113 ARG A CD  1 
ATOM   863   N  NE  . ARG A 1 113 ? 49.100  61.613  66.082  1.00 32.32  ? 113 ARG A NE  1 
ATOM   864   C  CZ  . ARG A 1 113 ? 49.244  62.809  66.644  1.00 36.97  ? 113 ARG A CZ  1 
ATOM   865   N  NH1 . ARG A 1 113 ? 49.986  63.763  66.078  1.00 26.35  ? 113 ARG A NH1 1 
ATOM   866   N  NH2 . ARG A 1 113 ? 48.609  63.066  67.784  1.00 30.49  ? 113 ARG A NH2 1 
ATOM   867   N  N   . PHE A 1 114 ? 51.089  59.611  59.858  1.00 31.45  ? 114 PHE A N   1 
ATOM   868   C  CA  . PHE A 1 114 ? 51.077  59.048  58.515  1.00 24.60  ? 114 PHE A CA  1 
ATOM   869   C  C   . PHE A 1 114 ? 52.512  58.759  58.102  1.00 31.41  ? 114 PHE A C   1 
ATOM   870   O  O   . PHE A 1 114 ? 53.248  59.673  57.685  1.00 29.32  ? 114 PHE A O   1 
ATOM   871   C  CB  . PHE A 1 114 ? 50.360  59.998  57.564  1.00 27.76  ? 114 PHE A CB  1 
ATOM   872   C  CG  . PHE A 1 114 ? 48.951  60.324  58.007  1.00 28.51  ? 114 PHE A CG  1 
ATOM   873   C  CD1 . PHE A 1 114 ? 47.901  59.458  57.717  1.00 28.63  ? 114 PHE A CD1 1 
ATOM   874   C  CD2 . PHE A 1 114 ? 48.680  61.469  58.748  1.00 25.96  ? 114 PHE A CD2 1 
ATOM   875   C  CE1 . PHE A 1 114 ? 46.594  59.745  58.127  1.00 29.99  ? 114 PHE A CE1 1 
ATOM   876   C  CE2 . PHE A 1 114 ? 47.377  61.771  59.169  1.00 28.41  ? 114 PHE A CE2 1 
ATOM   877   C  CZ  . PHE A 1 114 ? 46.331  60.906  58.861  1.00 28.95  ? 114 PHE A CZ  1 
ATOM   878   N  N   . PRO A 1 115 ? 52.950  57.495  58.187  1.00 34.12  ? 115 PRO A N   1 
ATOM   879   C  CA  . PRO A 1 115 ? 54.395  57.211  58.219  1.00 28.34  ? 115 PRO A CA  1 
ATOM   880   C  C   . PRO A 1 115 ? 55.108  57.459  56.895  1.00 29.53  ? 115 PRO A C   1 
ATOM   881   O  O   . PRO A 1 115 ? 56.341  57.529  56.887  1.00 32.74  ? 115 PRO A O   1 
ATOM   882   C  CB  . PRO A 1 115 ? 54.459  55.727  58.618  1.00 34.00  ? 115 PRO A CB  1 
ATOM   883   C  CG  . PRO A 1 115 ? 53.100  55.141  58.231  1.00 32.25  ? 115 PRO A CG  1 
ATOM   884   C  CD  . PRO A 1 115 ? 52.117  56.277  58.090  1.00 30.94  ? 115 PRO A CD  1 
ATOM   885   N  N   . ASN A 1 116 ? 54.392  57.610  55.787  1.00 28.53  ? 116 ASN A N   1 
ATOM   886   C  CA  . ASN A 1 116 ? 55.012  57.944  54.510  1.00 31.50  ? 116 ASN A CA  1 
ATOM   887   C  C   . ASN A 1 116 ? 54.882  59.428  54.141  1.00 31.48  ? 116 ASN A C   1 
ATOM   888   O  O   . ASN A 1 116 ? 55.362  59.834  53.079  1.00 35.34  ? 116 ASN A O   1 
ATOM   889   C  CB  . ASN A 1 116 ? 54.404  57.088  53.390  1.00 25.07  ? 116 ASN A CB  1 
ATOM   890   C  CG  . ASN A 1 116 ? 54.483  55.589  53.683  1.00 33.20  ? 116 ASN A CG  1 
ATOM   891   O  OD1 . ASN A 1 116 ? 53.468  54.890  53.678  1.00 33.11  ? 116 ASN A OD1 1 
ATOM   892   N  ND2 . ASN A 1 116 ? 55.686  55.097  53.947  1.00 29.19  ? 116 ASN A ND2 1 
ATOM   893   N  N   . ALA A 1 117 ? 54.245  60.239  54.981  1.00 31.10  ? 117 ALA A N   1 
ATOM   894   C  CA  . ALA A 1 117 ? 53.910  61.617  54.639  1.00 33.16  ? 117 ALA A CA  1 
ATOM   895   C  C   . ALA A 1 117 ? 55.089  62.559  54.881  1.00 31.95  ? 117 ALA A C   1 
ATOM   896   O  O   . ALA A 1 117 ? 55.672  62.571  55.967  1.00 29.49  ? 117 ALA A O   1 
ATOM   897   C  CB  . ALA A 1 117 ? 52.703  62.082  55.451  1.00 30.09  ? 117 ALA A CB  1 
ATOM   898   N  N   . ILE A 1 118 ? 55.435  63.349  53.865  1.00 26.99  ? 118 ILE A N   1 
ATOM   899   C  CA  . ILE A 1 118 ? 56.262  64.528  54.093  1.00 28.46  ? 118 ILE A CA  1 
ATOM   900   C  C   . ILE A 1 118 ? 55.403  65.601  54.748  1.00 30.98  ? 118 ILE A C   1 
ATOM   901   O  O   . ILE A 1 118 ? 54.270  65.856  54.311  1.00 26.11  ? 118 ILE A O   1 
ATOM   902   C  CB  . ILE A 1 118 ? 56.860  65.028  52.771  1.00 31.31  ? 118 ILE A CB  1 
ATOM   903   C  CG1 . ILE A 1 118 ? 57.924  64.053  52.271  1.00 29.99  ? 118 ILE A CG1 1 
ATOM   904   C  CG2 . ILE A 1 118 ? 57.416  66.431  52.925  1.00 25.98  ? 118 ILE A CG2 1 
ATOM   905   C  CD1 . ILE A 1 118 ? 58.460  64.414  50.918  1.00 33.83  ? 118 ILE A CD1 1 
ATOM   906   N  N   . HIS A 1 119 ? 55.932  66.234  55.800  1.00 26.17  ? 119 HIS A N   1 
ATOM   907   C  CA  . HIS A 1 119 ? 55.201  67.262  56.534  1.00 25.94  ? 119 HIS A CA  1 
ATOM   908   C  C   . HIS A 1 119 ? 55.711  68.633  56.104  1.00 25.49  ? 119 HIS A C   1 
ATOM   909   O  O   . HIS A 1 119 ? 56.907  68.920  56.226  1.00 27.39  ? 119 HIS A O   1 
ATOM   910   C  CB  . HIS A 1 119 ? 55.358  67.071  58.045  1.00 25.47  ? 119 HIS A CB  1 
ATOM   911   C  CG  . HIS A 1 119 ? 54.747  65.804  58.562  1.00 27.63  ? 119 HIS A CG  1 
ATOM   912   N  ND1 . HIS A 1 119 ? 55.153  64.557  58.134  1.00 30.14  ? 119 HIS A ND1 1 
ATOM   913   C  CD2 . HIS A 1 119 ? 53.766  65.588  59.473  1.00 24.15  ? 119 HIS A CD2 1 
ATOM   914   C  CE1 . HIS A 1 119 ? 54.437  63.629  58.744  1.00 29.90  ? 119 HIS A CE1 1 
ATOM   915   N  NE2 . HIS A 1 119 ? 53.585  64.228  59.557  1.00 29.40  ? 119 HIS A NE2 1 
ATOM   916   N  N   . ILE A 1 120 ? 54.818  69.481  55.602  1.00 26.11  ? 120 ILE A N   1 
ATOM   917   C  CA  . ILE A 1 120 ? 55.205  70.793  55.076  1.00 26.99  ? 120 ILE A CA  1 
ATOM   918   C  C   . ILE A 1 120 ? 54.643  71.883  55.985  1.00 22.68  ? 120 ILE A C   1 
ATOM   919   O  O   . ILE A 1 120 ? 53.439  71.904  56.273  1.00 22.14  ? 120 ILE A O   1 
ATOM   920   C  CB  . ILE A 1 120 ? 54.746  70.980  53.619  1.00 23.55  ? 120 ILE A CB  1 
ATOM   921   C  CG1 . ILE A 1 120 ? 55.198  69.787  52.771  1.00 25.72  ? 120 ILE A CG1 1 
ATOM   922   C  CG2 . ILE A 1 120 ? 55.308  72.293  53.053  1.00 25.56  ? 120 ILE A CG2 1 
ATOM   923   C  CD1 . ILE A 1 120 ? 54.740  69.821  51.301  1.00 22.71  ? 120 ILE A CD1 1 
ATOM   924   N  N   . VAL A 1 121 ? 55.522  72.778  56.440  1.00 20.97  ? 121 VAL A N   1 
ATOM   925   C  CA  . VAL A 1 121 ? 55.149  73.877  57.326  1.00 20.77  ? 121 VAL A CA  1 
ATOM   926   C  C   . VAL A 1 121 ? 56.227  74.954  57.215  1.00 21.07  ? 121 VAL A C   1 
ATOM   927   O  O   . VAL A 1 121 ? 57.361  74.681  56.801  1.00 20.26  ? 121 VAL A O   1 
ATOM   928   C  CB  . VAL A 1 121 ? 54.973  73.390  58.791  1.00 20.08  ? 121 VAL A CB  1 
ATOM   929   C  CG1 . VAL A 1 121 ? 56.329  73.162  59.448  1.00 16.44  ? 121 VAL A CG1 1 
ATOM   930   C  CG2 . VAL A 1 121 ? 54.184  74.381  59.597  1.00 16.48  ? 121 VAL A CG2 1 
ATOM   931   N  N   . ARG A 1 122 ? 55.870  76.195  57.571  1.00 19.63  ? 122 ARG A N   1 
ATOM   932   C  CA  . ARG A 1 122 ? 56.863  77.270  57.617  1.00 20.13  ? 122 ARG A CA  1 
ATOM   933   C  C   . ARG A 1 122 ? 57.944  76.974  58.655  1.00 20.48  ? 122 ARG A C   1 
ATOM   934   O  O   . ARG A 1 122 ? 57.643  76.655  59.807  1.00 21.22  ? 122 ARG A O   1 
ATOM   935   C  CB  . ARG A 1 122 ? 56.188  78.618  57.924  1.00 19.08  ? 122 ARG A CB  1 
ATOM   936   C  CG  . ARG A 1 122 ? 55.411  79.182  56.712  1.00 19.69  ? 122 ARG A CG  1 
ATOM   937   C  CD  . ARG A 1 122 ? 55.225  80.683  56.792  1.00 21.99  ? 122 ARG A CD  1 
ATOM   938   N  NE  . ARG A 1 122 ? 56.505  81.370  56.701  1.00 24.32  ? 122 ARG A NE  1 
ATOM   939   C  CZ  . ARG A 1 122 ? 56.646  82.687  56.675  1.00 27.93  ? 122 ARG A CZ  1 
ATOM   940   N  NH1 . ARG A 1 122 ? 55.604  83.490  56.729  1.00 24.27  ? 122 ARG A NH1 1 
ATOM   941   N  NH2 . ARG A 1 122 ? 57.865  83.209  56.574  1.00 28.63  ? 122 ARG A NH2 1 
ATOM   942   N  N   . ARG A 1 123 ? 59.210  77.064  58.233  1.00 21.21  ? 123 ARG A N   1 
ATOM   943   C  CA  . ARG A 1 123 ? 60.322  76.982  59.174  1.00 21.83  ? 123 ARG A CA  1 
ATOM   944   C  C   . ARG A 1 123 ? 60.076  77.812  60.425  1.00 22.23  ? 123 ARG A C   1 
ATOM   945   O  O   . ARG A 1 123 ? 60.214  77.308  61.550  1.00 22.64  ? 123 ARG A O   1 
ATOM   946   C  CB  . ARG A 1 123 ? 61.630  77.438  58.532  1.00 21.65  ? 123 ARG A CB  1 
ATOM   947   C  CG  . ARG A 1 123 ? 62.810  77.379  59.520  1.00 22.28  ? 123 ARG A CG  1 
ATOM   948   C  CD  . ARG A 1 123 ? 64.181  77.527  58.823  1.00 21.35  ? 123 ARG A CD  1 
ATOM   949   N  NE  . ARG A 1 123 ? 64.660  76.220  58.371  1.00 30.24  ? 123 ARG A NE  1 
ATOM   950   C  CZ  . ARG A 1 123 ? 65.109  75.271  59.182  1.00 28.56  ? 123 ARG A CZ  1 
ATOM   951   N  NH1 . ARG A 1 123 ? 65.256  75.485  60.485  1.00 26.02  ? 123 ARG A NH1 1 
ATOM   952   N  NH2 . ARG A 1 123 ? 65.417  74.081  58.681  1.00 31.08  ? 123 ARG A NH2 1 
ATOM   953   N  N   . CYS A 1 124 ? 59.688  79.084  60.259  1.00 19.22  ? 124 CYS A N   1 
ATOM   954   C  CA  . CYS A 1 124 ? 59.582  79.899  61.460  1.00 22.35  ? 124 CYS A CA  1 
ATOM   955   C  C   . CYS A 1 124 ? 58.468  79.425  62.387  1.00 22.00  ? 124 CYS A C   1 
ATOM   956   O  O   . CYS A 1 124 ? 58.563  79.669  63.590  1.00 20.35  ? 124 CYS A O   1 
ATOM   957   C  CB  . CYS A 1 124 ? 59.422  81.389  61.122  1.00 26.01  ? 124 CYS A CB  1 
ATOM   958   S  SG  . CYS A 1 124 ? 57.862  81.889  60.475  1.00 34.11  ? 124 CYS A SG  1 
ATOM   959   N  N   . GLU A 1 125 ? 57.457  78.705  61.872  1.00 21.17  ? 125 GLU A N   1 
ATOM   960   C  CA  . GLU A 1 125 ? 56.471  78.074  62.755  1.00 23.20  ? 125 GLU A CA  1 
ATOM   961   C  C   . GLU A 1 125 ? 57.079  76.898  63.509  1.00 19.12  ? 125 GLU A C   1 
ATOM   962   O  O   . GLU A 1 125 ? 56.923  76.779  64.724  1.00 21.06  ? 125 GLU A O   1 
ATOM   963   C  CB  . GLU A 1 125 ? 55.240  77.603  61.968  1.00 21.60  ? 125 GLU A CB  1 
ATOM   964   C  CG  . GLU A 1 125 ? 54.148  77.026  62.887  1.00 17.77  ? 125 GLU A CG  1 
ATOM   965   C  CD  . GLU A 1 125 ? 53.518  78.080  63.827  1.00 22.28  ? 125 GLU A CD  1 
ATOM   966   O  OE1 . GLU A 1 125 ? 53.779  79.304  63.657  1.00 18.13  ? 125 GLU A OE1 1 
ATOM   967   O  OE2 . GLU A 1 125 ? 52.733  77.688  64.718  1.00 21.81  ? 125 GLU A OE2 1 
ATOM   968   N  N   . TYR A 1 126 ? 57.766  76.011  62.795  1.00 21.78  ? 126 TYR A N   1 
ATOM   969   C  CA  . TYR A 1 126 ? 58.481  74.939  63.460  1.00 21.59  ? 126 TYR A CA  1 
ATOM   970   C  C   . TYR A 1 126 ? 59.423  75.490  64.523  1.00 22.95  ? 126 TYR A C   1 
ATOM   971   O  O   . TYR A 1 126 ? 59.416  75.034  65.667  1.00 23.87  ? 126 TYR A O   1 
ATOM   972   C  CB  . TYR A 1 126 ? 59.240  74.125  62.428  1.00 20.66  ? 126 TYR A CB  1 
ATOM   973   C  CG  . TYR A 1 126 ? 60.005  72.990  63.025  1.00 23.76  ? 126 TYR A CG  1 
ATOM   974   C  CD1 . TYR A 1 126 ? 59.380  71.783  63.304  1.00 25.23  ? 126 TYR A CD1 1 
ATOM   975   C  CD2 . TYR A 1 126 ? 61.368  73.116  63.305  1.00 29.20  ? 126 TYR A CD2 1 
ATOM   976   C  CE1 . TYR A 1 126 ? 60.086  70.728  63.854  1.00 31.48  ? 126 TYR A CE1 1 
ATOM   977   C  CE2 . TYR A 1 126 ? 62.085  72.076  63.848  1.00 25.77  ? 126 TYR A CE2 1 
ATOM   978   C  CZ  . TYR A 1 126 ? 61.437  70.876  64.119  1.00 32.89  ? 126 TYR A CZ  1 
ATOM   979   O  OH  . TYR A 1 126 ? 62.136  69.823  64.661  1.00 32.99  ? 126 TYR A OH  1 
ATOM   980   N  N   . GLU A 1 127 ? 60.214  76.508  64.167  1.00 22.94  ? 127 GLU A N   1 
ATOM   981   C  CA  . GLU A 1 127 ? 61.203  77.030  65.106  1.00 23.34  ? 127 GLU A CA  1 
ATOM   982   C  C   . GLU A 1 127 ? 60.537  77.695  66.309  1.00 23.31  ? 127 GLU A C   1 
ATOM   983   O  O   . GLU A 1 127 ? 61.029  77.570  67.434  1.00 24.44  ? 127 GLU A O   1 
ATOM   984   C  CB  . GLU A 1 127 ? 62.151  78.006  64.391  1.00 21.62  ? 127 GLU A CB  1 
ATOM   985   C  CG  . GLU A 1 127 ? 63.178  77.303  63.500  1.00 22.53  ? 127 GLU A CG  1 
ATOM   986   C  CD  . GLU A 1 127 ? 64.005  78.268  62.658  1.00 24.41  ? 127 GLU A CD  1 
ATOM   987   O  OE1 . GLU A 1 127 ? 63.653  79.456  62.573  1.00 23.80  ? 127 GLU A OE1 1 
ATOM   988   O  OE2 . GLU A 1 127 ? 65.020  77.834  62.070  1.00 33.14  ? 127 GLU A OE2 1 
ATOM   989   N  N   . TYR A 1 128 ? 59.415  78.402  66.099  1.00 22.62  ? 128 TYR A N   1 
ATOM   990   C  CA  . TYR A 1 128 ? 58.688  78.975  67.235  1.00 23.32  ? 128 TYR A CA  1 
ATOM   991   C  C   . TYR A 1 128 ? 58.053  77.881  68.094  1.00 24.89  ? 128 TYR A C   1 
ATOM   992   O  O   . TYR A 1 128 ? 58.089  77.951  69.332  1.00 22.16  ? 128 TYR A O   1 
ATOM   993   C  CB  . TYR A 1 128 ? 57.612  79.955  66.755  1.00 22.68  ? 128 TYR A CB  1 
ATOM   994   C  CG  . TYR A 1 128 ? 57.033  80.796  67.889  1.00 27.22  ? 128 TYR A CG  1 
ATOM   995   C  CD1 . TYR A 1 128 ? 57.749  81.879  68.410  1.00 21.90  ? 128 TYR A CD1 1 
ATOM   996   C  CD2 . TYR A 1 128 ? 55.799  80.489  68.458  1.00 19.88  ? 128 TYR A CD2 1 
ATOM   997   C  CE1 . TYR A 1 128 ? 57.243  82.633  69.441  1.00 23.86  ? 128 TYR A CE1 1 
ATOM   998   C  CE2 . TYR A 1 128 ? 55.297  81.238  69.508  1.00 20.70  ? 128 TYR A CE2 1 
ATOM   999   C  CZ  . TYR A 1 128 ? 56.026  82.303  69.994  1.00 21.97  ? 128 TYR A CZ  1 
ATOM   1000  O  OH  . TYR A 1 128 ? 55.534  83.077  71.014  1.00 22.68  ? 128 TYR A OH  1 
ATOM   1001  N  N   . ALA A 1 129 ? 57.475  76.861  67.448  1.00 24.62  ? 129 ALA A N   1 
ATOM   1002  C  CA  . ALA A 1 129 ? 56.867  75.746  68.169  1.00 25.07  ? 129 ALA A CA  1 
ATOM   1003  C  C   . ALA A 1 129 ? 57.840  75.154  69.178  1.00 24.35  ? 129 ALA A C   1 
ATOM   1004  O  O   . ALA A 1 129 ? 57.489  74.906  70.332  1.00 24.48  ? 129 ALA A O   1 
ATOM   1005  C  CB  . ALA A 1 129 ? 56.410  74.671  67.179  1.00 22.40  ? 129 ALA A CB  1 
ATOM   1006  N  N   . MET A 1 130 ? 59.080  74.935  68.746  1.00 26.00  ? 130 MET A N   1 
ATOM   1007  C  CA  . MET A 1 130 ? 60.106  74.367  69.602  1.00 25.29  ? 130 MET A CA  1 
ATOM   1008  C  C   . MET A 1 130 ? 60.553  75.324  70.701  1.00 26.89  ? 130 MET A C   1 
ATOM   1009  O  O   . MET A 1 130 ? 61.120  74.868  71.694  1.00 26.89  ? 130 MET A O   1 
ATOM   1010  C  CB  . MET A 1 130 ? 61.317  73.984  68.754  1.00 25.63  ? 130 MET A CB  1 
ATOM   1011  C  CG  . MET A 1 130 ? 61.116  72.790  67.852  1.00 30.50  ? 130 MET A CG  1 
ATOM   1012  S  SD  . MET A 1 130 ? 60.599  71.302  68.744  1.00 33.58  ? 130 MET A SD  1 
ATOM   1013  C  CE  . MET A 1 130 ? 60.194  70.242  67.345  1.00 37.61  ? 130 MET A CE  1 
ATOM   1014  N  N   . ALA A 1 131 ? 60.348  76.641  70.534  1.00 27.46  ? 131 ALA A N   1 
ATOM   1015  C  CA  . ALA A 1 131 ? 60.868  77.648  71.464  1.00 22.23  ? 131 ALA A CA  1 
ATOM   1016  C  C   . ALA A 1 131 ? 59.845  78.762  71.689  1.00 23.41  ? 131 ALA A C   1 
ATOM   1017  O  O   . ALA A 1 131 ? 60.126  79.943  71.455  1.00 22.30  ? 131 ALA A O   1 
ATOM   1018  C  CB  . ALA A 1 131 ? 62.190  78.213  70.938  1.00 24.28  ? 131 ALA A CB  1 
ATOM   1019  N  N   . PRO A 1 132 ? 58.641  78.422  72.161  1.00 24.93  ? 132 PRO A N   1 
ATOM   1020  C  CA  . PRO A 1 132 ? 57.588  79.439  72.293  1.00 23.15  ? 132 PRO A CA  1 
ATOM   1021  C  C   . PRO A 1 132 ? 57.871  80.415  73.434  1.00 23.47  ? 132 PRO A C   1 
ATOM   1022  O  O   . PRO A 1 132 ? 58.769  80.223  74.257  1.00 24.95  ? 132 PRO A O   1 
ATOM   1023  C  CB  . PRO A 1 132 ? 56.333  78.607  72.560  1.00 25.91  ? 132 PRO A CB  1 
ATOM   1024  C  CG  . PRO A 1 132 ? 56.874  77.409  73.320  1.00 27.96  ? 132 PRO A CG  1 
ATOM   1025  C  CD  . PRO A 1 132 ? 58.192  77.099  72.640  1.00 23.32  ? 132 PRO A CD  1 
ATOM   1026  N  N   . ASP A 1 133 ? 57.107  81.510  73.447  1.00 24.48  ? 133 ASP A N   1 
ATOM   1027  C  CA  . ASP A 1 133 ? 57.078  82.387  74.609  1.00 25.92  ? 133 ASP A CA  1 
ATOM   1028  C  C   . ASP A 1 133 ? 56.069  81.853  75.626  1.00 30.43  ? 133 ASP A C   1 
ATOM   1029  O  O   . ASP A 1 133 ? 55.313  80.916  75.344  1.00 28.32  ? 133 ASP A O   1 
ATOM   1030  C  CB  . ASP A 1 133 ? 56.741  83.820  74.200  1.00 24.87  ? 133 ASP A CB  1 
ATOM   1031  C  CG  . ASP A 1 133 ? 57.777  84.408  73.234  1.00 28.79  ? 133 ASP A CG  1 
ATOM   1032  O  OD1 . ASP A 1 133 ? 58.853  84.847  73.716  1.00 25.52  ? 133 ASP A OD1 1 
ATOM   1033  O  OD2 . ASP A 1 133 ? 57.510  84.411  71.998  1.00 26.24  ? 133 ASP A OD2 1 
ATOM   1034  N  N   . TRP A 1 134 ? 56.053  82.455  76.823  1.00 28.77  ? 134 TRP A N   1 
ATOM   1035  C  CA  . TRP A 1 134 ? 55.241  81.880  77.891  1.00 25.95  ? 134 TRP A CA  1 
ATOM   1036  C  C   . TRP A 1 134 ? 53.761  81.939  77.544  1.00 26.26  ? 134 TRP A C   1 
ATOM   1037  O  O   . TRP A 1 134 ? 53.032  80.976  77.787  1.00 27.08  ? 134 TRP A O   1 
ATOM   1038  C  CB  . TRP A 1 134 ? 55.523  82.561  79.239  1.00 30.03  ? 134 TRP A CB  1 
ATOM   1039  C  CG  . TRP A 1 134 ? 55.130  84.031  79.333  1.00 31.38  ? 134 TRP A CG  1 
ATOM   1040  C  CD1 . TRP A 1 134 ? 55.960  85.116  79.165  1.00 28.11  ? 134 TRP A CD1 1 
ATOM   1041  C  CD2 . TRP A 1 134 ? 53.826  84.567  79.632  1.00 26.81  ? 134 TRP A CD2 1 
ATOM   1042  N  NE1 . TRP A 1 134 ? 55.243  86.287  79.323  1.00 28.11  ? 134 TRP A NE1 1 
ATOM   1043  C  CE2 . TRP A 1 134 ? 53.936  85.976  79.612  1.00 27.05  ? 134 TRP A CE2 1 
ATOM   1044  C  CE3 . TRP A 1 134 ? 52.577  83.993  79.908  1.00 31.44  ? 134 TRP A CE3 1 
ATOM   1045  C  CZ2 . TRP A 1 134 ? 52.838  86.819  79.849  1.00 30.83  ? 134 TRP A CZ2 1 
ATOM   1046  C  CZ3 . TRP A 1 134 ? 51.485  84.837  80.144  1.00 29.74  ? 134 TRP A CZ3 1 
ATOM   1047  C  CH2 . TRP A 1 134 ? 51.626  86.231  80.118  1.00 32.05  ? 134 TRP A CH2 1 
ATOM   1048  N  N   . PHE A 1 135 ? 53.312  83.033  76.921  1.00 26.33  ? 135 PHE A N   1 
ATOM   1049  C  CA  . PHE A 1 135 ? 51.892  83.167  76.625  1.00 26.56  ? 135 PHE A CA  1 
ATOM   1050  C  C   . PHE A 1 135 ? 51.411  82.146  75.606  1.00 26.22  ? 135 PHE A C   1 
ATOM   1051  O  O   . PHE A 1 135 ? 50.220  81.861  75.575  1.00 26.14  ? 135 PHE A O   1 
ATOM   1052  C  CB  . PHE A 1 135 ? 51.552  84.594  76.157  1.00 26.85  ? 135 PHE A CB  1 
ATOM   1053  C  CG  . PHE A 1 135 ? 51.881  84.868  74.697  1.00 28.30  ? 135 PHE A CG  1 
ATOM   1054  C  CD1 . PHE A 1 135 ? 53.172  85.236  74.314  1.00 25.16  ? 135 PHE A CD1 1 
ATOM   1055  C  CD2 . PHE A 1 135 ? 50.898  84.754  73.711  1.00 25.07  ? 135 PHE A CD2 1 
ATOM   1056  C  CE1 . PHE A 1 135 ? 53.476  85.491  72.982  1.00 23.45  ? 135 PHE A CE1 1 
ATOM   1057  C  CE2 . PHE A 1 135 ? 51.205  84.998  72.376  1.00 23.94  ? 135 PHE A CE2 1 
ATOM   1058  C  CZ  . PHE A 1 135 ? 52.501  85.370  72.015  1.00 20.91  ? 135 PHE A CZ  1 
ATOM   1059  N  N   . SER A 1 136 ? 52.298  81.563  74.793  1.00 28.56  ? 136 SER A N   1 
ATOM   1060  C  CA  . SER A 1 136 ? 51.871  80.612  73.771  1.00 24.10  ? 136 SER A CA  1 
ATOM   1061  C  C   . SER A 1 136 ? 52.420  79.214  73.977  1.00 26.29  ? 136 SER A C   1 
ATOM   1062  O  O   . SER A 1 136 ? 52.095  78.326  73.183  1.00 25.37  ? 136 SER A O   1 
ATOM   1063  C  CB  . SER A 1 136 ? 52.285  81.088  72.370  1.00 26.81  ? 136 SER A CB  1 
ATOM   1064  O  OG  . SER A 1 136 ? 53.664  81.398  72.321  1.00 28.21  ? 136 SER A OG  1 
ATOM   1065  N  N   . ALA A 1 137 ? 53.247  78.994  75.006  1.00 26.68  ? 137 ALA A N   1 
ATOM   1066  C  CA  . ALA A 1 137 ? 53.853  77.678  75.213  1.00 26.40  ? 137 ALA A CA  1 
ATOM   1067  C  C   . ALA A 1 137 ? 52.800  76.583  75.355  1.00 26.00  ? 137 ALA A C   1 
ATOM   1068  O  O   . ALA A 1 137 ? 52.999  75.455  74.879  1.00 25.56  ? 137 ALA A O   1 
ATOM   1069  C  CB  . ALA A 1 137 ? 54.760  77.701  76.444  1.00 24.17  ? 137 ALA A CB  1 
ATOM   1070  N  N   . GLY A 1 138 ? 51.667  76.901  75.992  1.00 25.36  ? 138 GLY A N   1 
ATOM   1071  C  CA  . GLY A 1 138 ? 50.630  75.906  76.214  1.00 24.79  ? 138 GLY A CA  1 
ATOM   1072  C  C   . GLY A 1 138 ? 49.864  75.499  74.966  1.00 26.71  ? 138 GLY A C   1 
ATOM   1073  O  O   . GLY A 1 138 ? 49.279  74.414  74.938  1.00 29.27  ? 138 GLY A O   1 
ATOM   1074  N  N   . GLY A 1 139 ? 49.839  76.341  73.941  1.00 25.75  ? 139 GLY A N   1 
ATOM   1075  C  CA  . GLY A 1 139 ? 49.192  75.959  72.702  1.00 20.40  ? 139 GLY A CA  1 
ATOM   1076  C  C   . GLY A 1 139 ? 50.007  75.073  71.789  1.00 23.01  ? 139 GLY A C   1 
ATOM   1077  O  O   . GLY A 1 139 ? 49.535  74.741  70.697  1.00 25.50  ? 139 GLY A O   1 
ATOM   1078  N  N   . TYR A 1 140 ? 51.211  74.666  72.203  1.00 21.23  ? 140 TYR A N   1 
ATOM   1079  C  CA  . TYR A 1 140 ? 52.090  73.820  71.401  1.00 27.81  ? 140 TYR A CA  1 
ATOM   1080  C  C   . TYR A 1 140 ? 52.356  72.513  72.144  1.00 27.41  ? 140 TYR A C   1 
ATOM   1081  O  O   . TYR A 1 140 ? 52.969  72.524  73.214  1.00 26.35  ? 140 TYR A O   1 
ATOM   1082  C  CB  . TYR A 1 140 ? 53.407  74.542  71.105  1.00 24.04  ? 140 TYR A CB  1 
ATOM   1083  C  CG  . TYR A 1 140 ? 53.288  75.660  70.088  1.00 25.27  ? 140 TYR A CG  1 
ATOM   1084  C  CD1 . TYR A 1 140 ? 53.105  75.378  68.735  1.00 23.97  ? 140 TYR A CD1 1 
ATOM   1085  C  CD2 . TYR A 1 140 ? 53.352  76.993  70.482  1.00 21.32  ? 140 TYR A CD2 1 
ATOM   1086  C  CE1 . TYR A 1 140 ? 52.997  76.393  67.795  1.00 21.30  ? 140 TYR A CE1 1 
ATOM   1087  C  CE2 . TYR A 1 140 ? 53.256  78.012  69.554  1.00 21.98  ? 140 TYR A CE2 1 
ATOM   1088  C  CZ  . TYR A 1 140 ? 53.079  77.712  68.215  1.00 21.04  ? 140 TYR A CZ  1 
ATOM   1089  O  OH  . TYR A 1 140 ? 52.976  78.733  67.298  1.00 22.66  ? 140 TYR A OH  1 
ATOM   1090  N  N   . ILE A 1 141 ? 51.938  71.390  71.555  1.00 31.02  ? 141 ILE A N   1 
ATOM   1091  C  CA  . ILE A 1 141 ? 52.010  70.066  72.183  1.00 27.13  ? 141 ILE A CA  1 
ATOM   1092  C  C   . ILE A 1 141 ? 53.192  69.317  71.574  1.00 26.22  ? 141 ILE A C   1 
ATOM   1093  O  O   . ILE A 1 141 ? 53.091  68.770  70.475  1.00 27.74  ? 141 ILE A O   1 
ATOM   1094  C  CB  . ILE A 1 141 ? 50.701  69.293  71.993  1.00 28.22  ? 141 ILE A CB  1 
ATOM   1095  C  CG1 . ILE A 1 141 ? 49.510  70.178  72.395  1.00 27.89  ? 141 ILE A CG1 1 
ATOM   1096  C  CG2 . ILE A 1 141 ? 50.698  67.986  72.793  1.00 28.22  ? 141 ILE A CG2 1 
ATOM   1097  C  CD1 . ILE A 1 141 ? 49.527  70.628  73.825  1.00 24.35  ? 141 ILE A CD1 1 
ATOM   1098  N  N   . ARG A 1 142 ? 54.314  69.251  72.297  1.00 23.69  ? 142 ARG A N   1 
ATOM   1099  C  CA  . ARG A 1 142 ? 55.501  68.589  71.751  1.00 28.38  ? 142 ARG A CA  1 
ATOM   1100  C  C   . ARG A 1 142 ? 55.255  67.115  71.427  1.00 31.72  ? 142 ARG A C   1 
ATOM   1101  O  O   . ARG A 1 142 ? 55.864  66.582  70.494  1.00 34.32  ? 142 ARG A O   1 
ATOM   1102  C  CB  . ARG A 1 142 ? 56.684  68.696  72.718  1.00 33.06  ? 142 ARG A CB  1 
ATOM   1103  C  CG  . ARG A 1 142 ? 57.052  70.108  73.185  1.00 40.60  ? 142 ARG A CG  1 
ATOM   1104  C  CD  . ARG A 1 142 ? 58.297  70.632  72.490  1.00 45.21  ? 142 ARG A CD  1 
ATOM   1105  N  NE  . ARG A 1 142 ? 58.961  71.704  73.229  1.00 52.52  ? 142 ARG A NE  1 
ATOM   1106  C  CZ  . ARG A 1 142 ? 58.562  72.974  73.280  1.00 58.77  ? 142 ARG A CZ  1 
ATOM   1107  N  NH1 . ARG A 1 142 ? 57.444  73.383  72.695  1.00 34.67  ? 142 ARG A NH1 1 
ATOM   1108  N  NH2 . ARG A 1 142 ? 59.298  73.860  73.951  1.00 61.45  ? 142 ARG A NH2 1 
ATOM   1109  N  N   . ALA A 1 143 ? 54.387  66.431  72.176  1.00 27.38  ? 143 ALA A N   1 
ATOM   1110  C  CA  . ALA A 1 143 ? 54.075  65.039  71.838  1.00 32.52  ? 143 ALA A CA  1 
ATOM   1111  C  C   . ALA A 1 143 ? 53.481  64.892  70.437  1.00 28.62  ? 143 ALA A C   1 
ATOM   1112  O  O   . ALA A 1 143 ? 53.549  63.805  69.855  1.00 30.81  ? 143 ALA A O   1 
ATOM   1113  C  CB  . ALA A 1 143 ? 53.121  64.439  72.877  1.00 32.52  ? 143 ALA A CB  1 
ATOM   1114  N  N   . ASP A 1 144 ? 52.900  65.953  69.883  1.00 29.98  ? 144 ASP A N   1 
ATOM   1115  C  CA  . ASP A 1 144 ? 52.439  65.899  68.499  1.00 26.21  ? 144 ASP A CA  1 
ATOM   1116  C  C   . ASP A 1 144 ? 53.582  66.128  67.519  1.00 26.41  ? 144 ASP A C   1 
ATOM   1117  O  O   . ASP A 1 144 ? 53.898  65.259  66.704  1.00 28.44  ? 144 ASP A O   1 
ATOM   1118  C  CB  . ASP A 1 144 ? 51.342  66.940  68.253  1.00 26.32  ? 144 ASP A CB  1 
ATOM   1119  C  CG  . ASP A 1 144 ? 49.988  66.513  68.780  1.00 26.01  ? 144 ASP A CG  1 
ATOM   1120  O  OD1 . ASP A 1 144 ? 49.790  65.310  69.054  1.00 24.89  ? 144 ASP A OD1 1 
ATOM   1121  O  OD2 . ASP A 1 144 ? 49.106  67.393  68.875  1.00 26.81  ? 144 ASP A OD2 1 
ATOM   1122  N  N   . PHE A 1 145 ? 54.201  67.307  67.564  1.00 25.90  ? 145 PHE A N   1 
ATOM   1123  C  CA  . PHE A 1 145 ? 55.059  67.735  66.465  1.00 26.91  ? 145 PHE A CA  1 
ATOM   1124  C  C   . PHE A 1 145 ? 56.536  67.473  66.700  1.00 27.84  ? 145 PHE A C   1 
ATOM   1125  O  O   . PHE A 1 145 ? 57.322  67.639  65.769  1.00 30.99  ? 145 PHE A O   1 
ATOM   1126  C  CB  . PHE A 1 145 ? 54.866  69.225  66.175  1.00 25.34  ? 145 PHE A CB  1 
ATOM   1127  C  CG  . PHE A 1 145 ? 55.241  70.119  67.327  1.00 24.36  ? 145 PHE A CG  1 
ATOM   1128  C  CD1 . PHE A 1 145 ? 56.573  70.395  67.613  1.00 21.74  ? 145 PHE A CD1 1 
ATOM   1129  C  CD2 . PHE A 1 145 ? 54.256  70.668  68.133  1.00 23.12  ? 145 PHE A CD2 1 
ATOM   1130  C  CE1 . PHE A 1 145 ? 56.909  71.205  68.669  1.00 26.49  ? 145 PHE A CE1 1 
ATOM   1131  C  CE2 . PHE A 1 145 ? 54.588  71.478  69.192  1.00 23.10  ? 145 PHE A CE2 1 
ATOM   1132  C  CZ  . PHE A 1 145 ? 55.914  71.747  69.463  1.00 27.15  ? 145 PHE A CZ  1 
ATOM   1133  N  N   . ASP A 1 146 ? 56.949  67.105  67.910  1.00 28.39  ? 146 ASP A N   1 
ATOM   1134  C  CA  . ASP A 1 146 ? 58.364  66.852  68.174  1.00 31.03  ? 146 ASP A CA  1 
ATOM   1135  C  C   . ASP A 1 146 ? 58.599  65.348  68.134  1.00 34.45  ? 146 ASP A C   1 
ATOM   1136  O  O   . ASP A 1 146 ? 58.662  64.677  69.157  1.00 36.28  ? 146 ASP A O   1 
ATOM   1137  C  CB  . ASP A 1 146 ? 58.811  67.443  69.505  1.00 30.49  ? 146 ASP A CB  1 
ATOM   1138  C  CG  . ASP A 1 146 ? 60.317  67.338  69.690  1.00 34.10  ? 146 ASP A CG  1 
ATOM   1139  O  OD1 . ASP A 1 146 ? 61.018  67.072  68.688  1.00 32.26  ? 146 ASP A OD1 1 
ATOM   1140  O  OD2 . ASP A 1 146 ? 60.807  67.525  70.818  1.00 38.78  ? 146 ASP A OD2 1 
ATOM   1141  N  N   . ARG A 1 147 ? 58.764  64.826  66.919  1.00 34.62  ? 147 ARG A N   1 
ATOM   1142  C  CA  . ARG A 1 147 ? 58.931  63.397  66.700  1.00 33.96  ? 147 ARG A CA  1 
ATOM   1143  C  C   . ARG A 1 147 ? 60.097  63.184  65.745  1.00 40.06  ? 147 ARG A C   1 
ATOM   1144  O  O   . ARG A 1 147 ? 60.036  63.642  64.587  1.00 38.10  ? 147 ARG A O   1 
ATOM   1145  C  CB  . ARG A 1 147 ? 57.647  62.800  66.140  1.00 33.08  ? 147 ARG A CB  1 
ATOM   1146  C  CG  . ARG A 1 147 ? 56.490  62.806  67.130  1.00 34.72  ? 147 ARG A CG  1 
ATOM   1147  C  CD  . ARG A 1 147 ? 55.225  62.279  66.463  1.00 31.25  ? 147 ARG A CD  1 
ATOM   1148  N  NE  . ARG A 1 147 ? 54.052  62.402  67.316  1.00 30.19  ? 147 ARG A NE  1 
ATOM   1149  C  CZ  . ARG A 1 147 ? 53.055  61.530  67.327  1.00 31.62  ? 147 ARG A CZ  1 
ATOM   1150  N  NH1 . ARG A 1 147 ? 53.073  60.455  66.554  1.00 35.32  ? 147 ARG A NH1 1 
ATOM   1151  N  NH2 . ARG A 1 147 ? 52.009  61.750  68.118  1.00 32.91  ? 147 ARG A NH2 1 
ATOM   1152  N  N   . PRO A 1 148 ? 61.163  62.500  66.167  1.00 42.56  ? 148 PRO A N   1 
ATOM   1153  C  CA  . PRO A 1 148 ? 62.329  62.325  65.277  1.00 42.99  ? 148 PRO A CA  1 
ATOM   1154  C  C   . PRO A 1 148 ? 62.027  61.602  63.975  1.00 43.09  ? 148 PRO A C   1 
ATOM   1155  O  O   . PRO A 1 148 ? 62.718  61.844  62.977  1.00 48.04  ? 148 PRO A O   1 
ATOM   1156  C  CB  . PRO A 1 148 ? 63.301  61.519  66.148  1.00 41.65  ? 148 PRO A CB  1 
ATOM   1157  C  CG  . PRO A 1 148 ? 62.913  61.883  67.544  1.00 46.67  ? 148 PRO A CG  1 
ATOM   1158  C  CD  . PRO A 1 148 ? 61.413  61.957  67.508  1.00 41.99  ? 148 PRO A CD  1 
ATOM   1159  N  N   . ASP A 1 149 ? 61.027  60.719  63.945  1.00 38.09  ? 149 ASP A N   1 
ATOM   1160  C  CA  . ASP A 1 149 ? 60.729  59.967  62.731  1.00 40.50  ? 149 ASP A CA  1 
ATOM   1161  C  C   . ASP A 1 149 ? 60.104  60.813  61.614  1.00 39.88  ? 149 ASP A C   1 
ATOM   1162  O  O   . ASP A 1 149 ? 60.024  60.337  60.474  1.00 36.59  ? 149 ASP A O   1 
ATOM   1163  C  CB  . ASP A 1 149 ? 59.796  58.811  63.083  1.00 42.02  ? 149 ASP A CB  1 
ATOM   1164  C  CG  . ASP A 1 149 ? 58.494  59.291  63.727  1.00 50.26  ? 149 ASP A CG  1 
ATOM   1165  O  OD1 . ASP A 1 149 ? 58.538  59.715  64.909  1.00 50.74  ? 149 ASP A OD1 1 
ATOM   1166  O  OD2 . ASP A 1 149 ? 57.438  59.258  63.042  1.00 47.45  ? 149 ASP A OD2 1 
ATOM   1167  N  N   . VAL A 1 150 ? 59.658  62.042  61.889  1.00 35.04  ? 150 VAL A N   1 
ATOM   1168  C  CA  . VAL A 1 150 ? 58.920  62.803  60.880  1.00 34.96  ? 150 VAL A CA  1 
ATOM   1169  C  C   . VAL A 1 150 ? 59.867  63.354  59.812  1.00 29.08  ? 150 VAL A C   1 
ATOM   1170  O  O   . VAL A 1 150 ? 60.952  63.867  60.115  1.00 28.26  ? 150 VAL A O   1 
ATOM   1171  C  CB  . VAL A 1 150 ? 58.104  63.914  61.556  1.00 30.85  ? 150 VAL A CB  1 
ATOM   1172  C  CG1 . VAL A 1 150 ? 57.588  64.913  60.531  1.00 31.91  ? 150 VAL A CG1 1 
ATOM   1173  C  CG2 . VAL A 1 150 ? 56.938  63.292  62.328  1.00 32.88  ? 150 VAL A CG2 1 
ATOM   1174  N  N   . LYS A 1 151 ? 59.457  63.237  58.549  1.00 26.00  ? 151 LYS A N   1 
ATOM   1175  C  CA  . LYS A 1 151 ? 60.130  63.910  57.440  1.00 34.89  ? 151 LYS A CA  1 
ATOM   1176  C  C   . LYS A 1 151 ? 59.458  65.258  57.195  1.00 29.47  ? 151 LYS A C   1 
ATOM   1177  O  O   . LYS A 1 151 ? 58.266  65.309  56.863  1.00 30.45  ? 151 LYS A O   1 
ATOM   1178  C  CB  . LYS A 1 151 ? 60.105  63.068  56.163  1.00 29.00  ? 151 LYS A CB  1 
ATOM   1179  C  CG  . LYS A 1 151 ? 60.610  61.645  56.334  1.00 41.73  ? 151 LYS A CG  1 
ATOM   1180  C  CD  . LYS A 1 151 ? 60.455  60.819  55.053  1.00 50.76  ? 151 LYS A CD  1 
ATOM   1181  C  CE  . LYS A 1 151 ? 61.157  61.458  53.857  1.00 56.02  ? 151 LYS A CE  1 
ATOM   1182  N  NZ  . LYS A 1 151 ? 62.537  60.905  53.699  1.00 57.86  ? 151 LYS A NZ  1 
ATOM   1183  N  N   . TRP A 1 152 ? 60.223  66.338  57.354  1.00 22.64  ? 152 TRP A N   1 
ATOM   1184  C  CA  . TRP A 1 152 ? 59.714  67.699  57.259  1.00 26.11  ? 152 TRP A CA  1 
ATOM   1185  C  C   . TRP A 1 152 ? 60.223  68.362  55.988  1.00 28.72  ? 152 TRP A C   1 
ATOM   1186  O  O   . TRP A 1 152 ? 61.390  68.203  55.611  1.00 26.71  ? 152 TRP A O   1 
ATOM   1187  C  CB  . TRP A 1 152 ? 60.144  68.560  58.460  1.00 23.17  ? 152 TRP A CB  1 
ATOM   1188  C  CG  . TRP A 1 152 ? 59.478  68.267  59.804  1.00 29.25  ? 152 TRP A CG  1 
ATOM   1189  C  CD1 . TRP A 1 152 ? 60.023  67.567  60.854  1.00 28.33  ? 152 TRP A CD1 1 
ATOM   1190  C  CD2 . TRP A 1 152 ? 58.185  68.713  60.258  1.00 23.41  ? 152 TRP A CD2 1 
ATOM   1191  N  NE1 . TRP A 1 152 ? 59.147  67.549  61.916  1.00 29.25  ? 152 TRP A NE1 1 
ATOM   1192  C  CE2 . TRP A 1 152 ? 58.014  68.235  61.575  1.00 22.65  ? 152 TRP A CE2 1 
ATOM   1193  C  CE3 . TRP A 1 152 ? 57.166  69.478  59.684  1.00 25.83  ? 152 TRP A CE3 1 
ATOM   1194  C  CZ2 . TRP A 1 152 ? 56.861  68.488  62.321  1.00 25.94  ? 152 TRP A CZ2 1 
ATOM   1195  C  CZ3 . TRP A 1 152 ? 56.014  69.727  60.427  1.00 21.36  ? 152 TRP A CZ3 1 
ATOM   1196  C  CH2 . TRP A 1 152 ? 55.871  69.227  61.726  1.00 24.02  ? 152 TRP A CH2 1 
ATOM   1197  N  N   . HIS A 1 153 ? 59.355  69.113  55.329  1.00 28.39  ? 153 HIS A N   1 
ATOM   1198  C  CA  . HIS A 1 153 ? 59.798  70.139  54.400  1.00 27.13  ? 153 HIS A CA  1 
ATOM   1199  C  C   . HIS A 1 153 ? 59.488  71.478  55.059  1.00 25.37  ? 153 HIS A C   1 
ATOM   1200  O  O   . HIS A 1 153 ? 58.315  71.828  55.228  1.00 22.56  ? 153 HIS A O   1 
ATOM   1201  C  CB  . HIS A 1 153 ? 59.125  70.002  53.036  1.00 25.72  ? 153 HIS A CB  1 
ATOM   1202  C  CG  . HIS A 1 153 ? 59.549  71.053  52.058  1.00 28.84  ? 153 HIS A CG  1 
ATOM   1203  N  ND1 . HIS A 1 153 ? 60.763  71.708  52.157  1.00 26.85  ? 153 HIS A ND1 1 
ATOM   1204  C  CD2 . HIS A 1 153 ? 58.933  71.558  50.960  1.00 23.80  ? 153 HIS A CD2 1 
ATOM   1205  C  CE1 . HIS A 1 153 ? 60.871  72.579  51.168  1.00 23.05  ? 153 HIS A CE1 1 
ATOM   1206  N  NE2 . HIS A 1 153 ? 59.777  72.507  50.427  1.00 25.83  ? 153 HIS A NE2 1 
ATOM   1207  N  N   . LEU A 1 154 ? 60.534  72.225  55.435  1.00 22.62  ? 154 LEU A N   1 
ATOM   1208  C  CA  . LEU A 1 154 ? 60.357  73.487  56.151  1.00 23.22  ? 154 LEU A CA  1 
ATOM   1209  C  C   . LEU A 1 154 ? 60.483  74.651  55.168  1.00 22.45  ? 154 LEU A C   1 
ATOM   1210  O  O   . LEU A 1 154 ? 61.567  74.913  54.634  1.00 26.02  ? 154 LEU A O   1 
ATOM   1211  C  CB  . LEU A 1 154 ? 61.352  73.605  57.307  1.00 24.60  ? 154 LEU A CB  1 
ATOM   1212  C  CG  . LEU A 1 154 ? 61.174  72.528  58.391  1.00 23.35  ? 154 LEU A CG  1 
ATOM   1213  C  CD1 . LEU A 1 154 ? 62.204  72.632  59.535  1.00 25.68  ? 154 LEU A CD1 1 
ATOM   1214  C  CD2 . LEU A 1 154 ? 59.758  72.575  58.938  1.00 20.76  ? 154 LEU A CD2 1 
ATOM   1215  N  N   . LEU A 1 155 ? 59.374  75.353  54.938  1.00 20.26  ? 155 LEU A N   1 
ATOM   1216  C  CA  . LEU A 1 155 ? 59.351  76.418  53.944  1.00 22.79  ? 155 LEU A CA  1 
ATOM   1217  C  C   . LEU A 1 155 ? 60.055  77.663  54.466  1.00 23.53  ? 155 LEU A C   1 
ATOM   1218  O  O   . LEU A 1 155 ? 60.070  77.938  55.672  1.00 23.10  ? 155 LEU A O   1 
ATOM   1219  C  CB  . LEU A 1 155 ? 57.916  76.766  53.550  1.00 20.60  ? 155 LEU A CB  1 
ATOM   1220  C  CG  . LEU A 1 155 ? 57.057  75.618  52.992  1.00 22.52  ? 155 LEU A CG  1 
ATOM   1221  C  CD1 . LEU A 1 155 ? 55.631  76.092  52.738  1.00 17.46  ? 155 LEU A CD1 1 
ATOM   1222  C  CD2 . LEU A 1 155 ? 57.669  75.032  51.706  1.00 17.68  ? 155 LEU A CD2 1 
ATOM   1223  N  N   . GLU A 1 156 ? 60.643  78.413  53.544  1.00 22.56  ? 156 GLU A N   1 
ATOM   1224  C  CA  . GLU A 1 156 ? 61.325  79.667  53.853  1.00 28.18  ? 156 GLU A CA  1 
ATOM   1225  C  C   . GLU A 1 156 ? 60.428  80.841  53.472  1.00 25.39  ? 156 GLU A C   1 
ATOM   1226  O  O   . GLU A 1 156 ? 59.391  80.670  52.834  1.00 22.64  ? 156 GLU A O   1 
ATOM   1227  C  CB  . GLU A 1 156 ? 62.672  79.745  53.120  1.00 26.02  ? 156 GLU A CB  1 
ATOM   1228  C  CG  . GLU A 1 156 ? 63.579  78.557  53.413  1.00 28.30  ? 156 GLU A CG  1 
ATOM   1229  C  CD  . GLU A 1 156 ? 64.369  78.705  54.702  1.00 30.33  ? 156 GLU A CD  1 
ATOM   1230  O  OE1 . GLU A 1 156 ? 64.328  79.793  55.309  1.00 30.23  ? 156 GLU A OE1 1 
ATOM   1231  O  OE2 . GLU A 1 156 ? 65.039  77.729  55.105  1.00 34.32  ? 156 GLU A OE2 1 
ATOM   1232  N  N   . GLY A 1 157 ? 60.844  82.046  53.879  1.00 32.62  ? 157 GLY A N   1 
ATOM   1233  C  CA  . GLY A 1 157 ? 60.024  83.234  53.629  1.00 32.50  ? 157 GLY A CA  1 
ATOM   1234  C  C   . GLY A 1 157 ? 59.713  83.461  52.156  1.00 34.67  ? 157 GLY A C   1 
ATOM   1235  O  O   . GLY A 1 157 ? 58.622  83.931  51.805  1.00 41.35  ? 157 GLY A O   1 
ATOM   1236  N  N   . HIS A 1 158 ? 60.666  83.135  51.276  1.00 34.85  ? 158 HIS A N   1 
ATOM   1237  C  CA  . HIS A 1 158 ? 60.496  83.243  49.832  1.00 36.15  ? 158 HIS A CA  1 
ATOM   1238  C  C   . HIS A 1 158 ? 59.527  82.219  49.259  1.00 34.25  ? 158 HIS A C   1 
ATOM   1239  O  O   . HIS A 1 158 ? 59.231  82.276  48.061  1.00 29.31  ? 158 HIS A O   1 
ATOM   1240  C  CB  . HIS A 1 158 ? 61.863  83.092  49.157  1.00 38.07  ? 158 HIS A CB  1 
ATOM   1241  C  CG  . HIS A 1 158 ? 62.810  84.223  49.448  1.00 50.17  ? 158 HIS A CG  1 
ATOM   1242  N  ND1 . HIS A 1 158 ? 62.448  85.551  49.355  1.00 52.48  ? 158 HIS A ND1 1 
ATOM   1243  C  CD2 . HIS A 1 158 ? 64.089  84.219  49.896  1.00 50.67  ? 158 HIS A CD2 1 
ATOM   1244  C  CE1 . HIS A 1 158 ? 63.476  86.314  49.689  1.00 48.67  ? 158 HIS A CE1 1 
ATOM   1245  N  NE2 . HIS A 1 158 ? 64.484  85.530  50.028  1.00 49.35  ? 158 HIS A NE2 1 
ATOM   1246  N  N   . ASP A 1 159 ? 59.067  81.260  50.053  1.00 28.46  ? 159 ASP A N   1 
ATOM   1247  C  CA  . ASP A 1 159 ? 58.269  80.161  49.531  1.00 27.94  ? 159 ASP A CA  1 
ATOM   1248  C  C   . ASP A 1 159 ? 56.779  80.456  49.554  1.00 24.16  ? 159 ASP A C   1 
ATOM   1249  O  O   . ASP A 1 159 ? 55.979  79.521  49.453  1.00 25.39  ? 159 ASP A O   1 
ATOM   1250  C  CB  . ASP A 1 159 ? 58.539  78.871  50.323  1.00 23.93  ? 159 ASP A CB  1 
ATOM   1251  C  CG  . ASP A 1 159 ? 59.872  78.248  49.985  1.00 31.19  ? 159 ASP A CG  1 
ATOM   1252  O  OD1 . ASP A 1 159 ? 60.217  78.226  48.782  1.00 31.25  ? 159 ASP A OD1 1 
ATOM   1253  O  OD2 . ASP A 1 159 ? 60.578  77.792  50.919  1.00 26.98  ? 159 ASP A OD2 1 
ATOM   1254  N  N   . ASP A 1 160 ? 56.387  81.714  49.722  1.00 21.21  ? 160 ASP A N   1 
ATOM   1255  C  CA  . ASP A 1 160 ? 54.969  82.040  49.733  1.00 21.82  ? 160 ASP A CA  1 
ATOM   1256  C  C   . ASP A 1 160 ? 54.368  81.608  48.401  1.00 21.60  ? 160 ASP A C   1 
ATOM   1257  O  O   . ASP A 1 160 ? 54.994  81.750  47.353  1.00 22.78  ? 160 ASP A O   1 
ATOM   1258  C  CB  . ASP A 1 160 ? 54.752  83.535  49.986  1.00 18.95  ? 160 ASP A CB  1 
ATOM   1259  C  CG  . ASP A 1 160 ? 53.286  83.874  50.265  1.00 28.71  ? 160 ASP A CG  1 
ATOM   1260  O  OD1 . ASP A 1 160 ? 52.487  82.954  50.524  1.00 26.18  ? 160 ASP A OD1 1 
ATOM   1261  O  OD2 . ASP A 1 160 ? 52.922  85.065  50.242  1.00 30.92  ? 160 ASP A OD2 1 
ATOM   1262  N  N   . GLY A 1 161 ? 53.185  81.001  48.450  1.00 20.21  ? 161 GLY A N   1 
ATOM   1263  C  CA  . GLY A 1 161 ? 52.598  80.429  47.257  1.00 23.03  ? 161 GLY A CA  1 
ATOM   1264  C  C   . GLY A 1 161 ? 52.979  78.987  46.943  1.00 26.26  ? 161 GLY A C   1 
ATOM   1265  O  O   . GLY A 1 161 ? 52.474  78.445  45.948  1.00 24.69  ? 161 GLY A O   1 
ATOM   1266  N  N   . TYR A 1 162 ? 53.814  78.341  47.769  1.00 21.20  ? 162 TYR A N   1 
ATOM   1267  C  CA  . TYR A 1 162 ? 54.323  77.001  47.479  1.00 23.82  ? 162 TYR A CA  1 
ATOM   1268  C  C   . TYR A 1 162 ? 53.227  76.055  46.983  1.00 26.28  ? 162 TYR A C   1 
ATOM   1269  O  O   . TYR A 1 162 ? 52.161  75.912  47.604  1.00 23.33  ? 162 TYR A O   1 
ATOM   1270  C  CB  . TYR A 1 162 ? 55.001  76.419  48.720  1.00 21.73  ? 162 TYR A CB  1 
ATOM   1271  C  CG  . TYR A 1 162 ? 55.734  75.137  48.440  1.00 23.10  ? 162 TYR A CG  1 
ATOM   1272  C  CD1 . TYR A 1 162 ? 57.015  75.144  47.922  1.00 22.00  ? 162 TYR A CD1 1 
ATOM   1273  C  CD2 . TYR A 1 162 ? 55.135  73.914  48.687  1.00 21.62  ? 162 TYR A CD2 1 
ATOM   1274  C  CE1 . TYR A 1 162 ? 57.689  73.952  47.662  1.00 24.55  ? 162 TYR A CE1 1 
ATOM   1275  C  CE2 . TYR A 1 162 ? 55.784  72.722  48.417  1.00 22.63  ? 162 TYR A CE2 1 
ATOM   1276  C  CZ  . TYR A 1 162 ? 57.054  72.738  47.912  1.00 27.67  ? 162 TYR A CZ  1 
ATOM   1277  O  OH  . TYR A 1 162 ? 57.687  71.538  47.665  1.00 23.71  ? 162 TYR A OH  1 
ATOM   1278  N  N   . ASP A 1 163 ? 53.501  75.428  45.842  1.00 20.51  ? 163 ASP A N   1 
ATOM   1279  C  CA  . ASP A 1 163 ? 52.522  74.648  45.095  1.00 25.31  ? 163 ASP A CA  1 
ATOM   1280  C  C   . ASP A 1 163 ? 52.861  73.172  45.304  1.00 25.79  ? 163 ASP A C   1 
ATOM   1281  O  O   . ASP A 1 163 ? 53.871  72.681  44.787  1.00 22.84  ? 163 ASP A O   1 
ATOM   1282  C  CB  . ASP A 1 163 ? 52.542  75.054  43.618  1.00 25.98  ? 163 ASP A CB  1 
ATOM   1283  C  CG  . ASP A 1 163 ? 51.501  74.299  42.770  1.00 32.10  ? 163 ASP A CG  1 
ATOM   1284  O  OD1 . ASP A 1 163 ? 51.104  73.159  43.129  1.00 26.27  ? 163 ASP A OD1 1 
ATOM   1285  O  OD2 . ASP A 1 163 ? 51.087  74.856  41.731  1.00 30.39  ? 163 ASP A OD2 1 
ATOM   1286  N  N   . VAL A 1 164 ? 52.013  72.478  46.070  1.00 24.57  ? 164 VAL A N   1 
ATOM   1287  C  CA  . VAL A 1 164 ? 52.369  71.171  46.624  1.00 22.88  ? 164 VAL A CA  1 
ATOM   1288  C  C   . VAL A 1 164 ? 52.635  70.160  45.513  1.00 26.98  ? 164 VAL A C   1 
ATOM   1289  O  O   . VAL A 1 164 ? 53.668  69.476  45.509  1.00 26.50  ? 164 VAL A O   1 
ATOM   1290  C  CB  . VAL A 1 164 ? 51.267  70.669  47.576  1.00 23.35  ? 164 VAL A CB  1 
ATOM   1291  C  CG1 . VAL A 1 164 ? 51.553  69.238  47.968  1.00 25.49  ? 164 VAL A CG1 1 
ATOM   1292  C  CG2 . VAL A 1 164 ? 51.155  71.580  48.845  1.00 19.82  ? 164 VAL A CG2 1 
ATOM   1293  N  N   . PHE A 1 165 ? 51.700  70.029  44.572  1.00 23.95  ? 165 PHE A N   1 
ATOM   1294  C  CA  . PHE A 1 165 ? 51.877  69.125  43.446  1.00 30.20  ? 165 PHE A CA  1 
ATOM   1295  C  C   . PHE A 1 165 ? 52.465  69.797  42.214  1.00 31.57  ? 165 PHE A C   1 
ATOM   1296  O  O   . PHE A 1 165 ? 52.871  69.093  41.284  1.00 33.48  ? 165 PHE A O   1 
ATOM   1297  C  CB  . PHE A 1 165 ? 50.543  68.480  43.073  1.00 25.74  ? 165 PHE A CB  1 
ATOM   1298  C  CG  . PHE A 1 165 ? 50.046  67.499  44.095  1.00 30.87  ? 165 PHE A CG  1 
ATOM   1299  C  CD1 . PHE A 1 165 ? 50.679  66.276  44.276  1.00 30.88  ? 165 PHE A CD1 1 
ATOM   1300  C  CD2 . PHE A 1 165 ? 48.948  67.809  44.893  1.00 30.76  ? 165 PHE A CD2 1 
ATOM   1301  C  CE1 . PHE A 1 165 ? 50.207  65.364  45.229  1.00 31.59  ? 165 PHE A CE1 1 
ATOM   1302  C  CE2 . PHE A 1 165 ? 48.472  66.904  45.848  1.00 34.34  ? 165 PHE A CE2 1 
ATOM   1303  C  CZ  . PHE A 1 165 ? 49.099  65.684  46.014  1.00 31.04  ? 165 PHE A CZ  1 
ATOM   1304  N  N   . GLY A 1 166 ? 52.517  71.130  42.176  1.00 31.12  ? 166 GLY A N   1 
ATOM   1305  C  CA  . GLY A 1 166 ? 52.972  71.807  40.976  1.00 28.76  ? 166 GLY A CA  1 
ATOM   1306  C  C   . GLY A 1 166 ? 51.922  71.943  39.899  1.00 30.73  ? 166 GLY A C   1 
ATOM   1307  O  O   . GLY A 1 166 ? 52.264  72.102  38.732  1.00 31.57  ? 166 GLY A O   1 
ATOM   1308  N  N   . ASP A 1 167 ? 50.643  71.882  40.254  1.00 31.99  ? 167 ASP A N   1 
ATOM   1309  C  CA  . ASP A 1 167 ? 49.563  71.929  39.276  1.00 31.92  ? 167 ASP A CA  1 
ATOM   1310  C  C   . ASP A 1 167 ? 48.453  72.879  39.714  1.00 32.84  ? 167 ASP A C   1 
ATOM   1311  O  O   . ASP A 1 167 ? 47.328  72.776  39.213  1.00 30.23  ? 167 ASP A O   1 
ATOM   1312  C  CB  . ASP A 1 167 ? 48.995  70.530  39.053  1.00 30.77  ? 167 ASP A CB  1 
ATOM   1313  C  CG  . ASP A 1 167 ? 48.329  69.979  40.305  1.00 31.70  ? 167 ASP A CG  1 
ATOM   1314  O  OD1 . ASP A 1 167 ? 48.482  70.586  41.386  1.00 32.02  ? 167 ASP A OD1 1 
ATOM   1315  O  OD2 . ASP A 1 167 ? 47.670  68.933  40.218  1.00 30.76  ? 167 ASP A OD2 1 
ATOM   1316  N  N   . ASP A 1 168 ? 48.737  73.764  40.676  1.00 28.43  ? 168 ASP A N   1 
ATOM   1317  C  CA  . ASP A 1 168 ? 47.818  74.774  41.193  1.00 26.12  ? 168 ASP A CA  1 
ATOM   1318  C  C   . ASP A 1 168 ? 46.673  74.202  42.014  1.00 29.16  ? 168 ASP A C   1 
ATOM   1319  O  O   . ASP A 1 168 ? 45.737  74.939  42.326  1.00 30.26  ? 168 ASP A O   1 
ATOM   1320  C  CB  . ASP A 1 168 ? 47.208  75.631  40.083  1.00 27.97  ? 168 ASP A CB  1 
ATOM   1321  C  CG  . ASP A 1 168 ? 47.859  76.975  39.982  1.00 39.11  ? 168 ASP A CG  1 
ATOM   1322  O  OD1 . ASP A 1 168 ? 47.940  77.688  41.014  1.00 34.92  ? 168 ASP A OD1 1 
ATOM   1323  O  OD2 . ASP A 1 168 ? 48.319  77.301  38.867  1.00 47.55  ? 168 ASP A OD2 1 
ATOM   1324  N  N   . THR A 1 169 ? 46.722  72.922  42.385  1.00 27.71  ? 169 THR A N   1 
ATOM   1325  C  CA  . THR A 1 169 ? 45.631  72.341  43.169  1.00 28.99  ? 169 THR A CA  1 
ATOM   1326  C  C   . THR A 1 169 ? 45.664  72.838  44.609  1.00 26.10  ? 169 THR A C   1 
ATOM   1327  O  O   . THR A 1 169 ? 44.616  73.143  45.190  1.00 28.72  ? 169 THR A O   1 
ATOM   1328  C  CB  . THR A 1 169 ? 45.712  70.806  43.145  1.00 31.27  ? 169 THR A CB  1 
ATOM   1329  O  OG1 . THR A 1 169 ? 45.727  70.332  41.789  1.00 34.40  ? 169 THR A OG1 1 
ATOM   1330  C  CG2 . THR A 1 169 ? 44.500  70.205  43.862  1.00 36.14  ? 169 THR A CG2 1 
ATOM   1331  N  N   . ILE A 1 170 ? 46.858  72.911  45.208  1.00 27.50  ? 170 ILE A N   1 
ATOM   1332  C  CA  . ILE A 1 170 ? 47.035  73.328  46.600  1.00 26.75  ? 170 ILE A CA  1 
ATOM   1333  C  C   . ILE A 1 170 ? 48.239  74.254  46.694  1.00 25.71  ? 170 ILE A C   1 
ATOM   1334  O  O   . ILE A 1 170 ? 49.361  73.856  46.347  1.00 27.27  ? 170 ILE A O   1 
ATOM   1335  C  CB  . ILE A 1 170 ? 47.238  72.142  47.555  1.00 25.87  ? 170 ILE A CB  1 
ATOM   1336  C  CG1 . ILE A 1 170 ? 46.119  71.107  47.388  1.00 30.33  ? 170 ILE A CG1 1 
ATOM   1337  C  CG2 . ILE A 1 170 ? 47.289  72.629  49.005  1.00 23.33  ? 170 ILE A CG2 1 
ATOM   1338  C  CD1 . ILE A 1 170 ? 46.365  69.807  48.172  1.00 29.02  ? 170 ILE A CD1 1 
ATOM   1339  N  N   . ARG A 1 171 ? 48.027  75.458  47.226  1.00 21.91  ? 171 ARG A N   1 
ATOM   1340  C  CA  . ARG A 1 171 ? 49.103  76.422  47.433  1.00 24.99  ? 171 ARG A CA  1 
ATOM   1341  C  C   . ARG A 1 171 ? 49.056  76.974  48.849  1.00 24.02  ? 171 ARG A C   1 
ATOM   1342  O  O   . ARG A 1 171 ? 47.985  77.371  49.326  1.00 22.66  ? 171 ARG A O   1 
ATOM   1343  C  CB  . ARG A 1 171 ? 49.006  77.594  46.447  1.00 24.03  ? 171 ARG A CB  1 
ATOM   1344  C  CG  . ARG A 1 171 ? 49.451  77.303  45.031  1.00 28.79  ? 171 ARG A CG  1 
ATOM   1345  C  CD  . ARG A 1 171 ? 49.471  78.611  44.264  1.00 32.86  ? 171 ARG A CD  1 
ATOM   1346  N  NE  . ARG A 1 171 ? 49.845  78.428  42.876  1.00 33.48  ? 171 ARG A NE  1 
ATOM   1347  C  CZ  . ARG A 1 171 ? 51.057  78.648  42.389  1.00 43.04  ? 171 ARG A CZ  1 
ATOM   1348  N  NH1 . ARG A 1 171 ? 52.049  79.073  43.162  1.00 38.54  ? 171 ARG A NH1 1 
ATOM   1349  N  NH2 . ARG A 1 171 ? 51.284  78.426  41.094  1.00 42.59  ? 171 ARG A NH2 1 
ATOM   1350  N  N   . PHE A 1 172 ? 50.221  77.040  49.498  1.00 20.81  ? 172 PHE A N   1 
ATOM   1351  C  CA  . PHE A 1 172 ? 50.324  77.762  50.757  1.00 21.04  ? 172 PHE A CA  1 
ATOM   1352  C  C   . PHE A 1 172 ? 50.142  79.246  50.496  1.00 22.59  ? 172 PHE A C   1 
ATOM   1353  O  O   . PHE A 1 172 ? 50.768  79.797  49.587  1.00 23.91  ? 172 PHE A O   1 
ATOM   1354  C  CB  . PHE A 1 172 ? 51.682  77.550  51.420  1.00 19.79  ? 172 PHE A CB  1 
ATOM   1355  C  CG  . PHE A 1 172 ? 51.853  76.223  52.113  1.00 18.25  ? 172 PHE A CG  1 
ATOM   1356  C  CD1 . PHE A 1 172 ? 52.020  75.048  51.381  1.00 18.76  ? 172 PHE A CD1 1 
ATOM   1357  C  CD2 . PHE A 1 172 ? 51.936  76.168  53.491  1.00 18.06  ? 172 PHE A CD2 1 
ATOM   1358  C  CE1 . PHE A 1 172 ? 52.218  73.840  52.008  1.00 19.49  ? 172 PHE A CE1 1 
ATOM   1359  C  CE2 . PHE A 1 172 ? 52.140  74.958  54.137  1.00 20.45  ? 172 PHE A CE2 1 
ATOM   1360  C  CZ  . PHE A 1 172 ? 52.279  73.788  53.390  1.00 20.86  ? 172 PHE A CZ  1 
ATOM   1361  N  N   . ILE A 1 173 ? 49.317  79.904  51.300  1.00 18.28  ? 173 ILE A N   1 
ATOM   1362  C  CA  . ILE A 1 173 ? 49.201  81.366  51.271  1.00 19.08  ? 173 ILE A CA  1 
ATOM   1363  C  C   . ILE A 1 173 ? 49.614  81.873  52.651  1.00 19.37  ? 173 ILE A C   1 
ATOM   1364  O  O   . ILE A 1 173 ? 48.830  81.790  53.615  1.00 18.23  ? 173 ILE A O   1 
ATOM   1365  C  CB  . ILE A 1 173 ? 47.791  81.838  50.899  1.00 16.98  ? 173 ILE A CB  1 
ATOM   1366  C  CG1 . ILE A 1 173 ? 47.311  81.164  49.597  1.00 21.38  ? 173 ILE A CG1 1 
ATOM   1367  C  CG2 . ILE A 1 173 ? 47.741  83.385  50.796  1.00 16.46  ? 173 ILE A CG2 1 
ATOM   1368  C  CD1 . ILE A 1 173 ? 48.086  81.624  48.311  1.00 19.46  ? 173 ILE A CD1 1 
ATOM   1369  N  N   . PHE A 1 174 ? 50.833  82.421  52.755  1.00 16.27  ? 174 PHE A N   1 
ATOM   1370  C  CA  . PHE A 1 174 ? 51.368  82.800  54.068  1.00 19.78  ? 174 PHE A CA  1 
ATOM   1371  C  C   . PHE A 1 174 ? 50.518  83.902  54.687  1.00 18.60  ? 174 PHE A C   1 
ATOM   1372  O  O   . PHE A 1 174 ? 50.269  84.939  54.058  1.00 17.53  ? 174 PHE A O   1 
ATOM   1373  C  CB  . PHE A 1 174 ? 52.821  83.282  53.965  1.00 19.69  ? 174 PHE A CB  1 
ATOM   1374  C  CG  . PHE A 1 174 ? 53.808  82.201  53.638  1.00 22.02  ? 174 PHE A CG  1 
ATOM   1375  C  CD1 . PHE A 1 174 ? 53.402  80.880  53.480  1.00 18.73  ? 174 PHE A CD1 1 
ATOM   1376  C  CD2 . PHE A 1 174 ? 55.155  82.515  53.462  1.00 24.17  ? 174 PHE A CD2 1 
ATOM   1377  C  CE1 . PHE A 1 174 ? 54.323  79.885  53.171  1.00 19.73  ? 174 PHE A CE1 1 
ATOM   1378  C  CE2 . PHE A 1 174 ? 56.093  81.528  53.155  1.00 21.54  ? 174 PHE A CE2 1 
ATOM   1379  C  CZ  . PHE A 1 174 ? 55.677  80.209  53.003  1.00 21.94  ? 174 PHE A CZ  1 
ATOM   1380  N  N   . THR A 1 175 ? 50.074  83.680  55.921  1.00 18.79  ? 175 THR A N   1 
ATOM   1381  C  CA  . THR A 1 175 ? 49.242  84.642  56.645  1.00 16.99  ? 175 THR A CA  1 
ATOM   1382  C  C   . THR A 1 175 ? 49.747  84.807  58.078  1.00 20.89  ? 175 THR A C   1 
ATOM   1383  O  O   . THR A 1 175 ? 49.075  84.418  59.047  1.00 17.05  ? 175 THR A O   1 
ATOM   1384  C  CB  . THR A 1 175 ? 47.785  84.202  56.598  1.00 16.27  ? 175 THR A CB  1 
ATOM   1385  O  OG1 . THR A 1 175 ? 47.711  82.787  56.829  1.00 15.79  ? 175 THR A OG1 1 
ATOM   1386  C  CG2 . THR A 1 175 ? 47.234  84.485  55.227  1.00 17.95  ? 175 THR A CG2 1 
ATOM   1387  N  N   . PRO A 1 176 ? 50.940  85.388  58.247  1.00 17.27  ? 176 PRO A N   1 
ATOM   1388  C  CA  . PRO A 1 176 ? 51.492  85.557  59.598  1.00 20.32  ? 176 PRO A CA  1 
ATOM   1389  C  C   . PRO A 1 176 ? 50.573  86.387  60.478  1.00 21.64  ? 176 PRO A C   1 
ATOM   1390  O  O   . PRO A 1 176 ? 49.820  87.239  59.993  1.00 20.85  ? 176 PRO A O   1 
ATOM   1391  C  CB  . PRO A 1 176 ? 52.829  86.279  59.352  1.00 20.06  ? 176 PRO A CB  1 
ATOM   1392  C  CG  . PRO A 1 176 ? 52.637  86.984  58.023  1.00 25.65  ? 176 PRO A CG  1 
ATOM   1393  C  CD  . PRO A 1 176 ? 51.782  86.022  57.216  1.00 19.57  ? 176 PRO A CD  1 
ATOM   1394  N  N   . GLY A 1 177 ? 50.649  86.137  61.791  1.00 21.47  ? 177 GLY A N   1 
ATOM   1395  C  CA  . GLY A 1 177 ? 50.029  87.043  62.764  1.00 19.57  ? 177 GLY A CA  1 
ATOM   1396  C  C   . GLY A 1 177 ? 49.342  86.291  63.887  1.00 20.39  ? 177 GLY A C   1 
ATOM   1397  O  O   . GLY A 1 177 ? 49.723  86.395  65.060  1.00 23.51  ? 177 GLY A O   1 
ATOM   1398  N  N   . HIS A 1 178 ? 48.360  85.470  63.524  1.00 20.77  ? 178 HIS A N   1 
ATOM   1399  C  CA  . HIS A 1 178 ? 47.798  84.545  64.502  1.00 23.76  ? 178 HIS A CA  1 
ATOM   1400  C  C   . HIS A 1 178 ? 48.874  83.662  65.135  1.00 22.54  ? 178 HIS A C   1 
ATOM   1401  O  O   . HIS A 1 178 ? 48.882  83.453  66.356  1.00 24.84  ? 178 HIS A O   1 
ATOM   1402  C  CB  . HIS A 1 178 ? 46.732  83.669  63.863  1.00 19.17  ? 178 HIS A CB  1 
ATOM   1403  C  CG  . HIS A 1 178 ? 46.317  82.548  64.747  1.00 27.14  ? 178 HIS A CG  1 
ATOM   1404  N  ND1 . HIS A 1 178 ? 45.558  82.748  65.876  1.00 22.22  ? 178 HIS A ND1 1 
ATOM   1405  C  CD2 . HIS A 1 178 ? 46.612  81.228  64.715  1.00 28.06  ? 178 HIS A CD2 1 
ATOM   1406  C  CE1 . HIS A 1 178 ? 45.373  81.592  66.481  1.00 27.87  ? 178 HIS A CE1 1 
ATOM   1407  N  NE2 . HIS A 1 178 ? 45.993  80.654  65.793  1.00 23.84  ? 178 HIS A NE2 1 
ATOM   1408  N  N   . ALA A 1 179 ? 49.773  83.134  64.321  1.00 19.16  ? 179 ALA A N   1 
ATOM   1409  C  CA  . ALA A 1 179 ? 50.991  82.485  64.779  1.00 19.06  ? 179 ALA A CA  1 
ATOM   1410  C  C   . ALA A 1 179 ? 52.112  82.961  63.865  1.00 19.62  ? 179 ALA A C   1 
ATOM   1411  O  O   . ALA A 1 179 ? 51.854  83.363  62.730  1.00 19.23  ? 179 ALA A O   1 
ATOM   1412  C  CB  . ALA A 1 179 ? 50.856  80.954  64.749  1.00 15.86  ? 179 ALA A CB  1 
ATOM   1413  N  N   . PRO A 1 180 ? 53.366  82.933  64.329  1.00 20.19  ? 180 PRO A N   1 
ATOM   1414  C  CA  . PRO A 1 180 ? 54.422  83.507  63.476  1.00 21.66  ? 180 PRO A CA  1 
ATOM   1415  C  C   . PRO A 1 180 ? 54.480  82.857  62.107  1.00 20.99  ? 180 PRO A C   1 
ATOM   1416  O  O   . PRO A 1 180 ? 54.604  83.564  61.097  1.00 22.15  ? 180 PRO A O   1 
ATOM   1417  C  CB  . PRO A 1 180 ? 55.700  83.282  64.289  1.00 21.80  ? 180 PRO A CB  1 
ATOM   1418  C  CG  . PRO A 1 180 ? 55.205  83.043  65.717  1.00 19.50  ? 180 PRO A CG  1 
ATOM   1419  C  CD  . PRO A 1 180 ? 53.899  82.378  65.581  1.00 17.77  ? 180 PRO A CD  1 
ATOM   1420  N  N   . GLY A 1 181 ? 54.346  81.539  62.032  1.00 19.71  ? 181 GLY A N   1 
ATOM   1421  C  CA  . GLY A 1 181 ? 54.467  80.870  60.748  1.00 17.70  ? 181 GLY A CA  1 
ATOM   1422  C  C   . GLY A 1 181 ? 53.162  80.400  60.143  1.00 21.16  ? 181 GLY A C   1 
ATOM   1423  O  O   . GLY A 1 181 ? 53.143  79.463  59.327  1.00 19.17  ? 181 GLY A O   1 
ATOM   1424  N  N   . HIS A 1 182 ? 52.073  81.069  60.515  1.00 18.43  ? 182 HIS A N   1 
ATOM   1425  C  CA  . HIS A 1 182 ? 50.753  80.636  60.090  1.00 17.72  ? 182 HIS A CA  1 
ATOM   1426  C  C   . HIS A 1 182 ? 50.593  80.801  58.597  1.00 20.32  ? 182 HIS A C   1 
ATOM   1427  O  O   . HIS A 1 182 ? 50.981  81.823  58.016  1.00 20.01  ? 182 HIS A O   1 
ATOM   1428  C  CB  . HIS A 1 182 ? 49.654  81.429  60.790  1.00 18.29  ? 182 HIS A CB  1 
ATOM   1429  C  CG  . HIS A 1 182 ? 48.279  81.005  60.393  1.00 21.52  ? 182 HIS A CG  1 
ATOM   1430  N  ND1 . HIS A 1 182 ? 47.716  81.336  59.178  1.00 21.21  ? 182 HIS A ND1 1 
ATOM   1431  C  CD2 . HIS A 1 182 ? 47.362  80.244  61.039  1.00 22.42  ? 182 HIS A CD2 1 
ATOM   1432  C  CE1 . HIS A 1 182 ? 46.513  80.793  59.092  1.00 22.12  ? 182 HIS A CE1 1 
ATOM   1433  N  NE2 . HIS A 1 182 ? 46.279  80.120  60.204  1.00 20.99  ? 182 HIS A NE2 1 
ATOM   1434  N  N   . SER A 1 183 ? 49.973  79.803  57.985  1.00 21.05  ? 183 SER A N   1 
ATOM   1435  C  CA  . SER A 1 183 ? 49.665  79.831  56.571  1.00 17.52  ? 183 SER A CA  1 
ATOM   1436  C  C   . SER A 1 183 ? 48.218  79.419  56.329  1.00 21.74  ? 183 SER A C   1 
ATOM   1437  O  O   . SER A 1 183 ? 47.702  78.504  56.983  1.00 21.31  ? 183 SER A O   1 
ATOM   1438  C  CB  . SER A 1 183 ? 50.606  78.913  55.818  1.00 18.39  ? 183 SER A CB  1 
ATOM   1439  O  OG  . SER A 1 183 ? 50.365  79.054  54.437  1.00 29.53  ? 183 SER A OG  1 
ATOM   1440  N  N   . SER A 1 184 ? 47.568  80.113  55.394  1.00 20.40  ? 184 SER A N   1 
ATOM   1441  C  CA  . SER A 1 184 ? 46.292  79.704  54.828  1.00 19.52  ? 184 SER A CA  1 
ATOM   1442  C  C   . SER A 1 184 ? 46.561  78.849  53.583  1.00 22.91  ? 184 SER A C   1 
ATOM   1443  O  O   . SER A 1 184 ? 47.710  78.617  53.205  1.00 20.20  ? 184 SER A O   1 
ATOM   1444  C  CB  . SER A 1 184 ? 45.439  80.929  54.480  1.00 16.60  ? 184 SER A CB  1 
ATOM   1445  O  OG  . SER A 1 184 ? 45.262  81.781  55.603  1.00 20.19  ? 184 SER A OG  1 
ATOM   1446  N  N   . PHE A 1 185 ? 45.496  78.387  52.916  1.00 23.20  ? 185 PHE A N   1 
ATOM   1447  C  CA  . PHE A 1 185 ? 45.663  77.589  51.705  1.00 21.81  ? 185 PHE A CA  1 
ATOM   1448  C  C   . PHE A 1 185 ? 44.675  78.026  50.631  1.00 25.11  ? 185 PHE A C   1 
ATOM   1449  O  O   . PHE A 1 185 ? 43.483  78.232  50.899  1.00 21.15  ? 185 PHE A O   1 
ATOM   1450  C  CB  . PHE A 1 185 ? 45.482  76.088  51.993  1.00 21.12  ? 185 PHE A CB  1 
ATOM   1451  C  CG  . PHE A 1 185 ? 46.479  75.548  52.969  1.00 19.26  ? 185 PHE A CG  1 
ATOM   1452  C  CD1 . PHE A 1 185 ? 47.709  75.112  52.541  1.00 18.25  ? 185 PHE A CD1 1 
ATOM   1453  C  CD2 . PHE A 1 185 ? 46.195  75.508  54.320  1.00 21.70  ? 185 PHE A CD2 1 
ATOM   1454  C  CE1 . PHE A 1 185 ? 48.655  74.652  53.446  1.00 21.86  ? 185 PHE A CE1 1 
ATOM   1455  C  CE2 . PHE A 1 185 ? 47.127  75.034  55.239  1.00 19.50  ? 185 PHE A CE2 1 
ATOM   1456  C  CZ  . PHE A 1 185 ? 48.356  74.601  54.792  1.00 22.96  ? 185 PHE A CZ  1 
ATOM   1457  N  N   . LEU A 1 186 ? 45.172  78.150  49.407  1.00 21.21  ? 186 LEU A N   1 
ATOM   1458  C  CA  . LEU A 1 186 ? 44.304  78.333  48.254  1.00 22.74  ? 186 LEU A CA  1 
ATOM   1459  C  C   . LEU A 1 186 ? 44.171  77.004  47.526  1.00 23.21  ? 186 LEU A C   1 
ATOM   1460  O  O   . LEU A 1 186 ? 45.173  76.406  47.110  1.00 26.71  ? 186 LEU A O   1 
ATOM   1461  C  CB  . LEU A 1 186 ? 44.831  79.402  47.314  1.00 19.33  ? 186 LEU A CB  1 
ATOM   1462  C  CG  . LEU A 1 186 ? 43.907  79.662  46.120  1.00 24.19  ? 186 LEU A CG  1 
ATOM   1463  C  CD1 . LEU A 1 186 ? 42.593  80.215  46.618  1.00 20.37  ? 186 LEU A CD1 1 
ATOM   1464  C  CD2 . LEU A 1 186 ? 44.540  80.651  45.141  1.00 18.88  ? 186 LEU A CD2 1 
ATOM   1465  N  N   . LEU A 1 187 ? 42.945  76.553  47.362  1.00 23.61  ? 187 LEU A N   1 
ATOM   1466  C  CA  . LEU A 1 187 ? 42.677  75.317  46.647  1.00 24.38  ? 187 LEU A CA  1 
ATOM   1467  C  C   . LEU A 1 187 ? 41.978  75.651  45.336  1.00 26.42  ? 187 LEU A C   1 
ATOM   1468  O  O   . LEU A 1 187 ? 41.304  76.675  45.219  1.00 30.18  ? 187 LEU A O   1 
ATOM   1469  C  CB  . LEU A 1 187 ? 41.829  74.366  47.496  1.00 24.89  ? 187 LEU A CB  1 
ATOM   1470  C  CG  . LEU A 1 187 ? 42.567  73.397  48.422  1.00 28.08  ? 187 LEU A CG  1 
ATOM   1471  C  CD1 . LEU A 1 187 ? 43.521  74.110  49.339  1.00 20.04  ? 187 LEU A CD1 1 
ATOM   1472  C  CD2 . LEU A 1 187 ? 41.549  72.575  49.241  1.00 30.43  ? 187 LEU A CD2 1 
ATOM   1473  N  N   . ARG A 1 188 ? 42.196  74.813  44.331  1.00 28.37  ? 188 ARG A N   1 
ATOM   1474  C  CA  . ARG A 1 188 ? 41.515  74.915  43.046  1.00 31.19  ? 188 ARG A CA  1 
ATOM   1475  C  C   . ARG A 1 188 ? 41.026  73.516  42.696  1.00 35.30  ? 188 ARG A C   1 
ATOM   1476  O  O   . ARG A 1 188 ? 41.833  72.601  42.494  1.00 31.84  ? 188 ARG A O   1 
ATOM   1477  C  CB  . ARG A 1 188 ? 42.435  75.475  41.961  1.00 27.92  ? 188 ARG A CB  1 
ATOM   1478  C  CG  . ARG A 1 188 ? 42.603  77.000  42.021  1.00 31.26  ? 188 ARG A CG  1 
ATOM   1479  C  CD  . ARG A 1 188 ? 43.623  77.515  41.010  1.00 31.54  ? 188 ARG A CD  1 
ATOM   1480  N  NE  . ARG A 1 188 ? 43.821  78.959  41.097  1.00 33.94  ? 188 ARG A NE  1 
ATOM   1481  C  CZ  . ARG A 1 188 ? 42.927  79.863  40.712  1.00 37.26  ? 188 ARG A CZ  1 
ATOM   1482  N  NH1 . ARG A 1 188 ? 41.765  79.509  40.184  1.00 30.57  ? 188 ARG A NH1 1 
ATOM   1483  N  NH2 . ARG A 1 188 ? 43.202  81.153  40.866  1.00 33.35  ? 188 ARG A NH2 1 
ATOM   1484  N  N   . LEU A 1 189 ? 39.717  73.349  42.664  1.00 36.06  ? 189 LEU A N   1 
ATOM   1485  C  CA  . LEU A 1 189 ? 39.095  72.087  42.326  1.00 33.63  ? 189 LEU A CA  1 
ATOM   1486  C  C   . LEU A 1 189 ? 38.376  72.204  40.979  1.00 34.71  ? 189 LEU A C   1 
ATOM   1487  O  O   . LEU A 1 189 ? 37.865  73.281  40.631  1.00 30.15  ? 189 LEU A O   1 
ATOM   1488  C  CB  . LEU A 1 189 ? 38.120  71.680  43.435  1.00 31.28  ? 189 LEU A CB  1 
ATOM   1489  C  CG  . LEU A 1 189 ? 38.809  71.582  44.805  1.00 36.11  ? 189 LEU A CG  1 
ATOM   1490  C  CD1 . LEU A 1 189 ? 37.881  71.911  45.960  1.00 28.38  ? 189 LEU A CD1 1 
ATOM   1491  C  CD2 . LEU A 1 189 ? 39.387  70.191  45.021  1.00 32.66  ? 189 LEU A CD2 1 
ATOM   1492  N  N   . PRO A 1 190 ? 38.348  71.117  40.191  1.00 36.22  ? 190 PRO A N   1 
ATOM   1493  C  CA  . PRO A 1 190 ? 37.838  71.218  38.809  1.00 34.18  ? 190 PRO A CA  1 
ATOM   1494  C  C   . PRO A 1 190 ? 36.417  71.758  38.708  1.00 35.69  ? 190 PRO A C   1 
ATOM   1495  O  O   . PRO A 1 190 ? 36.141  72.599  37.847  1.00 38.75  ? 190 PRO A O   1 
ATOM   1496  C  CB  . PRO A 1 190 ? 37.935  69.769  38.302  1.00 34.10  ? 190 PRO A CB  1 
ATOM   1497  C  CG  . PRO A 1 190 ? 39.035  69.165  39.122  1.00 33.28  ? 190 PRO A CG  1 
ATOM   1498  C  CD  . PRO A 1 190 ? 38.857  69.765  40.487  1.00 34.86  ? 190 PRO A CD  1 
ATOM   1499  N  N   . GLU A 1 191 ? 35.505  71.316  39.571  1.00 35.50  ? 191 GLU A N   1 
ATOM   1500  C  CA  . GLU A 1 191 ? 34.134  71.808  39.499  1.00 36.62  ? 191 GLU A CA  1 
ATOM   1501  C  C   . GLU A 1 191 ? 33.904  73.044  40.361  1.00 34.83  ? 191 GLU A C   1 
ATOM   1502  O  O   . GLU A 1 191 ? 33.309  74.020  39.899  1.00 37.56  ? 191 GLU A O   1 
ATOM   1503  C  CB  . GLU A 1 191 ? 33.157  70.702  39.913  1.00 36.62  ? 191 GLU A CB  1 
ATOM   1504  C  CG  . GLU A 1 191 ? 33.309  69.435  39.087  1.00 42.74  ? 191 GLU A CG  1 
ATOM   1505  C  CD  . GLU A 1 191 ? 32.147  68.471  39.271  1.00 51.57  ? 191 GLU A CD  1 
ATOM   1506  O  OE1 . GLU A 1 191 ? 31.105  68.889  39.836  1.00 54.17  ? 191 GLU A OE1 1 
ATOM   1507  O  OE2 . GLU A 1 191 ? 32.288  67.291  38.870  1.00 54.20  ? 191 GLU A OE2 1 
ATOM   1508  N  N   . THR A 1 192 ? 34.331  73.015  41.622  1.00 35.35  ? 192 THR A N   1 
ATOM   1509  C  CA  . THR A 1 192 ? 34.055  74.148  42.505  1.00 30.65  ? 192 THR A CA  1 
ATOM   1510  C  C   . THR A 1 192 ? 34.846  75.387  42.103  1.00 30.63  ? 192 THR A C   1 
ATOM   1511  O  O   . THR A 1 192 ? 34.405  76.513  42.357  1.00 31.40  ? 192 THR A O   1 
ATOM   1512  C  CB  . THR A 1 192 ? 34.372  73.765  43.948  1.00 27.76  ? 192 THR A CB  1 
ATOM   1513  O  OG1 . THR A 1 192 ? 33.736  72.515  44.259  1.00 32.49  ? 192 THR A OG1 1 
ATOM   1514  C  CG2 . THR A 1 192 ? 33.931  74.842  44.932  1.00 29.11  ? 192 THR A CG2 1 
ATOM   1515  N  N   . GLY A 1 193 ? 36.004  75.211  41.478  1.00 28.91  ? 193 GLY A N   1 
ATOM   1516  C  CA  . GLY A 1 193 ? 36.924  76.309  41.319  1.00 31.22  ? 193 GLY A CA  1 
ATOM   1517  C  C   . GLY A 1 193 ? 37.698  76.578  42.603  1.00 32.31  ? 193 GLY A C   1 
ATOM   1518  O  O   . GLY A 1 193 ? 37.954  75.676  43.409  1.00 28.72  ? 193 GLY A O   1 
ATOM   1519  N  N   . PRO A 1 194 ? 38.071  77.835  42.821  1.00 28.83  ? 194 PRO A N   1 
ATOM   1520  C  CA  . PRO A 1 194 ? 38.976  78.153  43.934  1.00 26.46  ? 194 PRO A CA  1 
ATOM   1521  C  C   . PRO A 1 194 ? 38.266  78.148  45.280  1.00 27.08  ? 194 PRO A C   1 
ATOM   1522  O  O   . PRO A 1 194 ? 37.146  78.643  45.426  1.00 23.51  ? 194 PRO A O   1 
ATOM   1523  C  CB  . PRO A 1 194 ? 39.492  79.561  43.598  1.00 26.79  ? 194 PRO A CB  1 
ATOM   1524  C  CG  . PRO A 1 194 ? 38.572  80.108  42.561  1.00 33.76  ? 194 PRO A CG  1 
ATOM   1525  C  CD  . PRO A 1 194 ? 37.669  79.022  42.044  1.00 31.44  ? 194 PRO A CD  1 
ATOM   1526  N  N   . VAL A 1 195 ? 38.949  77.578  46.266  1.00 22.27  ? 195 VAL A N   1 
ATOM   1527  C  CA  . VAL A 1 195 ? 38.483  77.510  47.640  1.00 23.26  ? 195 VAL A CA  1 
ATOM   1528  C  C   . VAL A 1 195 ? 39.598  78.036  48.520  1.00 24.39  ? 195 VAL A C   1 
ATOM   1529  O  O   . VAL A 1 195 ? 40.737  77.553  48.432  1.00 24.33  ? 195 VAL A O   1 
ATOM   1530  C  CB  . VAL A 1 195 ? 38.123  76.067  48.048  1.00 25.91  ? 195 VAL A CB  1 
ATOM   1531  C  CG1 . VAL A 1 195 ? 37.592  76.028  49.495  1.00 17.43  ? 195 VAL A CG1 1 
ATOM   1532  C  CG2 . VAL A 1 195 ? 37.161  75.454  47.031  1.00 21.74  ? 195 VAL A CG2 1 
ATOM   1533  N  N   . LEU A 1 196 ? 39.280  79.026  49.351  1.00 22.60  ? 196 LEU A N   1 
ATOM   1534  C  CA  . LEU A 1 196 ? 40.262  79.674  50.216  1.00 23.35  ? 196 LEU A CA  1 
ATOM   1535  C  C   . LEU A 1 196 ? 40.036  79.197  51.646  1.00 23.62  ? 196 LEU A C   1 
ATOM   1536  O  O   . LEU A 1 196 ? 39.049  79.578  52.288  1.00 25.16  ? 196 LEU A O   1 
ATOM   1537  C  CB  . LEU A 1 196 ? 40.177  81.197  50.116  1.00 16.86  ? 196 LEU A CB  1 
ATOM   1538  C  CG  . LEU A 1 196 ? 41.054  81.986  51.086  1.00 17.80  ? 196 LEU A CG  1 
ATOM   1539  C  CD1 . LEU A 1 196 ? 42.483  81.472  51.093  1.00 18.55  ? 196 LEU A CD1 1 
ATOM   1540  C  CD2 . LEU A 1 196 ? 41.029  83.448  50.730  1.00 21.50  ? 196 LEU A CD2 1 
ATOM   1541  N  N   . LEU A 1 197 ? 40.958  78.374  52.141  1.00 20.47  ? 197 LEU A N   1 
ATOM   1542  C  CA  . LEU A 1 197 ? 40.927  77.909  53.520  1.00 22.10  ? 197 LEU A CA  1 
ATOM   1543  C  C   . LEU A 1 197 ? 41.681  78.931  54.365  1.00 22.51  ? 197 LEU A C   1 
ATOM   1544  O  O   . LEU A 1 197 ? 42.911  78.948  54.391  1.00 24.76  ? 197 LEU A O   1 
ATOM   1545  C  CB  . LEU A 1 197 ? 41.539  76.517  53.625  1.00 21.34  ? 197 LEU A CB  1 
ATOM   1546  C  CG  . LEU A 1 197 ? 40.887  75.417  52.784  1.00 21.62  ? 197 LEU A CG  1 
ATOM   1547  C  CD1 . LEU A 1 197 ? 41.578  74.077  53.004  1.00 20.78  ? 197 LEU A CD1 1 
ATOM   1548  C  CD2 . LEU A 1 197 ? 39.373  75.317  53.089  1.00 24.86  ? 197 LEU A CD2 1 
ATOM   1549  N  N   . ALA A 1 198 ? 40.953  79.796  55.064  1.00 21.89  ? 198 ALA A N   1 
ATOM   1550  C  CA  . ALA A 1 198 ? 41.647  80.835  55.819  1.00 24.15  ? 198 ALA A CA  1 
ATOM   1551  C  C   . ALA A 1 198 ? 42.363  80.260  57.027  1.00 24.02  ? 198 ALA A C   1 
ATOM   1552  O  O   . ALA A 1 198 ? 43.386  80.809  57.453  1.00 24.08  ? 198 ALA A O   1 
ATOM   1553  C  CB  . ALA A 1 198 ? 40.680  81.928  56.256  1.00 21.28  ? 198 ALA A CB  1 
ATOM   1554  N  N   . VAL A 1 199 ? 41.854  79.144  57.566  1.00 27.63  ? 199 VAL A N   1 
ATOM   1555  C  CA  . VAL A 1 199 ? 42.287  78.586  58.841  1.00 19.35  ? 199 VAL A CA  1 
ATOM   1556  C  C   . VAL A 1 199 ? 42.250  79.721  59.859  1.00 24.72  ? 199 VAL A C   1 
ATOM   1557  O  O   . VAL A 1 199 ? 41.276  80.490  59.913  1.00 25.20  ? 199 VAL A O   1 
ATOM   1558  C  CB  . VAL A 1 199 ? 43.671  77.912  58.734  1.00 27.15  ? 199 VAL A CB  1 
ATOM   1559  C  CG1 . VAL A 1 199 ? 43.880  76.869  59.856  1.00 27.22  ? 199 VAL A CG1 1 
ATOM   1560  C  CG2 . VAL A 1 199 ? 43.804  77.230  57.393  1.00 22.60  ? 199 VAL A CG2 1 
ATOM   1561  N  N   . ASP A 1 200 ? 43.300  79.871  60.661  1.00 22.80  ? 200 ASP A N   1 
ATOM   1562  C  CA  . ASP A 1 200 ? 43.203  80.799  61.774  1.00 23.27  ? 200 ASP A CA  1 
ATOM   1563  C  C   . ASP A 1 200 ? 43.671  82.203  61.417  1.00 23.92  ? 200 ASP A C   1 
ATOM   1564  O  O   . ASP A 1 200 ? 43.814  83.042  62.318  1.00 22.70  ? 200 ASP A O   1 
ATOM   1565  C  CB  . ASP A 1 200 ? 43.962  80.260  62.988  1.00 25.90  ? 200 ASP A CB  1 
ATOM   1566  C  CG  . ASP A 1 200 ? 43.281  79.028  63.601  1.00 27.05  ? 200 ASP A CG  1 
ATOM   1567  O  OD1 . ASP A 1 200 ? 42.210  78.613  63.109  1.00 29.26  ? 200 ASP A OD1 1 
ATOM   1568  O  OD2 . ASP A 1 200 ? 43.826  78.471  64.563  1.00 28.11  ? 200 ASP A OD2 1 
ATOM   1569  N  N   . ALA A 1 201 ? 43.875  82.493  60.129  1.00 22.01  ? 201 ALA A N   1 
ATOM   1570  C  CA  . ALA A 1 201 ? 44.023  83.889  59.738  1.00 22.61  ? 201 ALA A CA  1 
ATOM   1571  C  C   . ALA A 1 201 ? 42.712  84.657  59.847  1.00 24.31  ? 201 ALA A C   1 
ATOM   1572  O  O   . ALA A 1 201 ? 42.747  85.889  59.948  1.00 25.87  ? 201 ALA A O   1 
ATOM   1573  C  CB  . ALA A 1 201 ? 44.577  83.996  58.318  1.00 21.34  ? 201 ALA A CB  1 
ATOM   1574  N  N   . ALA A 1 202 ? 41.566  83.960  59.861  1.00 25.87  ? 202 ALA A N   1 
ATOM   1575  C  CA  . ALA A 1 202 ? 40.261  84.599  60.064  1.00 21.67  ? 202 ALA A CA  1 
ATOM   1576  C  C   . ALA A 1 202 ? 39.326  83.572  60.703  1.00 26.08  ? 202 ALA A C   1 
ATOM   1577  O  O   . ALA A 1 202 ? 38.687  82.786  59.995  1.00 26.29  ? 202 ALA A O   1 
ATOM   1578  C  CB  . ALA A 1 202 ? 39.690  85.120  58.754  1.00 22.15  ? 202 ALA A CB  1 
ATOM   1579  N  N   . TYR A 1 203 ? 39.248  83.597  62.034  1.00 24.90  ? 203 TYR A N   1 
ATOM   1580  C  CA  . TYR A 1 203 ? 38.392  82.674  62.777  1.00 29.60  ? 203 TYR A CA  1 
ATOM   1581  C  C   . TYR A 1 203 ? 36.944  82.687  62.269  1.00 32.97  ? 203 TYR A C   1 
ATOM   1582  O  O   . TYR A 1 203 ? 36.330  81.628  62.061  1.00 29.90  ? 203 TYR A O   1 
ATOM   1583  C  CB  . TYR A 1 203 ? 38.403  83.049  64.255  1.00 31.40  ? 203 TYR A CB  1 
ATOM   1584  C  CG  . TYR A 1 203 ? 39.600  82.642  65.091  1.00 31.45  ? 203 TYR A CG  1 
ATOM   1585  C  CD1 . TYR A 1 203 ? 40.265  81.447  64.874  1.00 34.13  ? 203 TYR A CD1 1 
ATOM   1586  C  CD2 . TYR A 1 203 ? 40.007  83.439  66.159  1.00 39.11  ? 203 TYR A CD2 1 
ATOM   1587  C  CE1 . TYR A 1 203 ? 41.327  81.070  65.674  1.00 32.63  ? 203 TYR A CE1 1 
ATOM   1588  C  CE2 . TYR A 1 203 ? 41.062  83.076  66.963  1.00 40.86  ? 203 TYR A CE2 1 
ATOM   1589  C  CZ  . TYR A 1 203 ? 41.716  81.888  66.720  1.00 39.30  ? 203 TYR A CZ  1 
ATOM   1590  O  OH  . TYR A 1 203 ? 42.763  81.523  67.532  1.00 39.17  ? 203 TYR A OH  1 
ATOM   1591  N  N   . THR A 1 204 ? 36.373  83.886  62.103  1.00 27.91  ? 204 THR A N   1 
ATOM   1592  C  CA  . THR A 1 204 ? 34.946  84.079  61.865  1.00 31.20  ? 204 THR A CA  1 
ATOM   1593  C  C   . THR A 1 204 ? 34.746  85.185  60.840  1.00 30.53  ? 204 THR A C   1 
ATOM   1594  O  O   . THR A 1 204 ? 35.658  85.960  60.549  1.00 30.86  ? 204 THR A O   1 
ATOM   1595  C  CB  . THR A 1 204 ? 34.179  84.459  63.150  1.00 34.66  ? 204 THR A CB  1 
ATOM   1596  O  OG1 . THR A 1 204 ? 34.500  85.810  63.527  1.00 31.60  ? 204 THR A OG1 1 
ATOM   1597  C  CG2 . THR A 1 204 ? 34.506  83.517  64.303  1.00 31.84  ? 204 THR A CG2 1 
ATOM   1598  N  N   . THR A 1 205 ? 33.516  85.278  60.318  1.00 34.07  ? 205 THR A N   1 
ATOM   1599  C  CA  . THR A 1 205 ? 33.166  86.372  59.413  1.00 34.40  ? 205 THR A CA  1 
ATOM   1600  C  C   . THR A 1 205 ? 33.393  87.729  60.062  1.00 32.43  ? 205 THR A C   1 
ATOM   1601  O  O   . THR A 1 205 ? 33.699  88.700  59.362  1.00 33.39  ? 205 THR A O   1 
ATOM   1602  C  CB  . THR A 1 205 ? 31.703  86.271  58.977  1.00 38.54  ? 205 THR A CB  1 
ATOM   1603  O  OG1 . THR A 1 205 ? 30.872  86.443  60.129  1.00 41.71  ? 205 THR A OG1 1 
ATOM   1604  C  CG2 . THR A 1 205 ? 31.400  84.916  58.349  1.00 35.43  ? 205 THR A CG2 1 
ATOM   1605  N  N   . ASP A 1 206 ? 33.216  87.823  61.388  1.00 31.06  ? 206 ASP A N   1 
ATOM   1606  C  CA  . ASP A 1 206 ? 33.511  89.069  62.095  1.00 33.28  ? 206 ASP A CA  1 
ATOM   1607  C  C   . ASP A 1 206 ? 34.982  89.455  61.958  1.00 35.92  ? 206 ASP A C   1 
ATOM   1608  O  O   . ASP A 1 206 ? 35.315  90.648  61.865  1.00 31.29  ? 206 ASP A O   1 
ATOM   1609  C  CB  . ASP A 1 206 ? 33.144  88.935  63.574  1.00 35.65  ? 206 ASP A CB  1 
ATOM   1610  C  CG  . ASP A 1 206 ? 31.704  89.363  63.868  1.00 41.52  ? 206 ASP A CG  1 
ATOM   1611  O  OD1 . ASP A 1 206 ? 30.969  89.730  62.920  1.00 37.23  ? 206 ASP A OD1 1 
ATOM   1612  O  OD2 . ASP A 1 206 ? 31.315  89.346  65.061  1.00 41.49  ? 206 ASP A OD2 1 
ATOM   1613  N  N   . HIS A 1 207 ? 35.885  88.465  61.983  1.00 32.00  ? 207 HIS A N   1 
ATOM   1614  C  CA  . HIS A 1 207 ? 37.293  88.768  61.761  1.00 32.49  ? 207 HIS A CA  1 
ATOM   1615  C  C   . HIS A 1 207 ? 37.514  89.237  60.336  1.00 24.49  ? 207 HIS A C   1 
ATOM   1616  O  O   . HIS A 1 207 ? 38.139  90.275  60.107  1.00 27.21  ? 207 HIS A O   1 
ATOM   1617  C  CB  . HIS A 1 207 ? 38.163  87.553  62.092  1.00 28.32  ? 207 HIS A CB  1 
ATOM   1618  C  CG  . HIS A 1 207 ? 38.216  87.257  63.552  1.00 34.40  ? 207 HIS A CG  1 
ATOM   1619  N  ND1 . HIS A 1 207 ? 37.343  86.383  64.165  1.00 34.18  ? 207 HIS A ND1 1 
ATOM   1620  C  CD2 . HIS A 1 207 ? 39.005  87.755  64.535  1.00 37.41  ? 207 HIS A CD2 1 
ATOM   1621  C  CE1 . HIS A 1 207 ? 37.603  86.337  65.459  1.00 36.28  ? 207 HIS A CE1 1 
ATOM   1622  N  NE2 . HIS A 1 207 ? 38.604  87.163  65.711  1.00 40.04  ? 207 HIS A NE2 1 
ATOM   1623  N  N   . TRP A 1 208 ? 36.964  88.505  59.374  1.00 28.56  ? 208 TRP A N   1 
ATOM   1624  C  CA  . TRP A 1 208 ? 37.123  88.852  57.961  1.00 28.14  ? 208 TRP A CA  1 
ATOM   1625  C  C   . TRP A 1 208 ? 36.604  90.258  57.662  1.00 31.28  ? 208 TRP A C   1 
ATOM   1626  O  O   . TRP A 1 208 ? 37.197  90.985  56.852  1.00 27.83  ? 208 TRP A O   1 
ATOM   1627  C  CB  . TRP A 1 208 ? 36.400  87.812  57.108  1.00 28.91  ? 208 TRP A CB  1 
ATOM   1628  C  CG  . TRP A 1 208 ? 36.510  87.961  55.617  1.00 28.62  ? 208 TRP A CG  1 
ATOM   1629  C  CD1 . TRP A 1 208 ? 35.662  88.649  54.789  1.00 27.60  ? 208 TRP A CD1 1 
ATOM   1630  C  CD2 . TRP A 1 208 ? 37.486  87.345  54.765  1.00 28.86  ? 208 TRP A CD2 1 
ATOM   1631  N  NE1 . TRP A 1 208 ? 36.066  88.519  53.480  1.00 23.72  ? 208 TRP A NE1 1 
ATOM   1632  C  CE2 . TRP A 1 208 ? 37.180  87.723  53.437  1.00 25.18  ? 208 TRP A CE2 1 
ATOM   1633  C  CE3 . TRP A 1 208 ? 38.579  86.507  54.996  1.00 21.03  ? 208 TRP A CE3 1 
ATOM   1634  C  CZ2 . TRP A 1 208 ? 37.940  87.303  52.351  1.00 24.75  ? 208 TRP A CZ2 1 
ATOM   1635  C  CZ3 . TRP A 1 208 ? 39.325  86.094  53.931  1.00 23.62  ? 208 TRP A CZ3 1 
ATOM   1636  C  CH2 . TRP A 1 208 ? 39.010  86.493  52.614  1.00 26.15  ? 208 TRP A CH2 1 
ATOM   1637  N  N   . ASP A 1 209 ? 35.509  90.665  58.317  1.00 28.11  ? 209 ASP A N   1 
ATOM   1638  C  CA  . ASP A 1 209 ? 34.923  91.985  58.109  1.00 28.63  ? 209 ASP A CA  1 
ATOM   1639  C  C   . ASP A 1 209 ? 35.536  93.057  59.005  1.00 31.25  ? 209 ASP A C   1 
ATOM   1640  O  O   . ASP A 1 209 ? 35.036  94.186  59.036  1.00 34.51  ? 209 ASP A O   1 
ATOM   1641  C  CB  . ASP A 1 209 ? 33.408  91.954  58.342  1.00 32.54  ? 209 ASP A CB  1 
ATOM   1642  C  CG  . ASP A 1 209 ? 32.681  91.018  57.396  1.00 37.90  ? 209 ASP A CG  1 
ATOM   1643  O  OD1 . ASP A 1 209 ? 33.094  90.879  56.220  1.00 39.22  ? 209 ASP A OD1 1 
ATOM   1644  O  OD2 . ASP A 1 209 ? 31.655  90.450  57.826  1.00 44.69  ? 209 ASP A OD2 1 
ATOM   1645  N  N   . GLU A 1 210 ? 36.570  92.720  59.768  1.00 30.14  ? 210 GLU A N   1 
ATOM   1646  C  CA  . GLU A 1 210 ? 37.319  93.700  60.544  1.00 29.33  ? 210 GLU A CA  1 
ATOM   1647  C  C   . GLU A 1 210 ? 36.453  94.309  61.652  1.00 35.57  ? 210 GLU A C   1 
ATOM   1648  O  O   . GLU A 1 210 ? 36.513  95.512  61.926  1.00 36.84  ? 210 GLU A O   1 
ATOM   1649  C  CB  . GLU A 1 210 ? 37.924  94.771  59.624  1.00 30.01  ? 210 GLU A CB  1 
ATOM   1650  C  CG  . GLU A 1 210 ? 38.900  94.174  58.626  1.00 29.64  ? 210 GLU A CG  1 
ATOM   1651  C  CD  . GLU A 1 210 ? 39.603  95.190  57.736  1.00 30.22  ? 210 GLU A CD  1 
ATOM   1652  O  OE1 . GLU A 1 210 ? 39.313  96.403  57.804  1.00 30.59  ? 210 GLU A OE1 1 
ATOM   1653  O  OE2 . GLU A 1 210 ? 40.467  94.755  56.965  1.00 28.21  ? 210 GLU A OE2 1 
ATOM   1654  N  N   . LYS A 1 211 ? 35.636  93.455  62.280  1.00 36.94  ? 211 LYS A N   1 
ATOM   1655  C  CA  . LYS A 1 211 ? 34.848  93.778  63.463  1.00 33.71  ? 211 LYS A CA  1 
ATOM   1656  C  C   . LYS A 1 211 ? 35.331  93.040  64.702  1.00 37.01  ? 211 LYS A C   1 
ATOM   1657  O  O   . LYS A 1 211 ? 34.766  93.242  65.779  1.00 40.45  ? 211 LYS A O   1 
ATOM   1658  C  CB  . LYS A 1 211 ? 33.368  93.444  63.229  1.00 34.03  ? 211 LYS A CB  1 
ATOM   1659  C  CG  . LYS A 1 211 ? 32.737  94.155  62.059  1.00 31.56  ? 211 LYS A CG  1 
ATOM   1660  C  CD  . LYS A 1 211 ? 31.336  93.627  61.794  1.00 42.14  ? 211 LYS A CD  1 
ATOM   1661  C  CE  . LYS A 1 211 ? 30.766  94.162  60.479  1.00 52.39  ? 211 LYS A CE  1 
ATOM   1662  N  NZ  . LYS A 1 211 ? 29.413  93.606  60.163  1.00 54.26  ? 211 LYS A NZ  1 
ATOM   1663  N  N   . ALA A 1 212 ? 36.340  92.179  64.570  1.00 38.37  ? 212 ALA A N   1 
ATOM   1664  C  CA  . ALA A 1 212 ? 36.938  91.466  65.687  1.00 34.31  ? 212 ALA A CA  1 
ATOM   1665  C  C   . ALA A 1 212 ? 38.418  91.266  65.411  1.00 35.70  ? 212 ALA A C   1 
ATOM   1666  O  O   . ALA A 1 212 ? 38.831  91.135  64.258  1.00 34.64  ? 212 ALA A O   1 
ATOM   1667  C  CB  . ALA A 1 212 ? 36.282  90.099  65.907  1.00 38.10  ? 212 ALA A CB  1 
ATOM   1668  N  N   . LEU A 1 213 ? 39.226  91.219  66.506  1.00 37.09  ? 213 LEU A N   1 
ATOM   1669  C  CA  . LEU A 1 213 ? 40.610  90.780  66.515  1.00 35.43  ? 213 LEU A CA  1 
ATOM   1670  C  C   . LEU A 1 213 ? 40.703  89.355  67.049  1.00 37.13  ? 213 LEU A C   1 
ATOM   1671  O  O   . LEU A 1 213 ? 39.917  88.966  67.913  1.00 35.33  ? 213 LEU A O   1 
ATOM   1672  C  CB  . LEU A 1 213 ? 41.470  91.701  67.386  1.00 33.90  ? 213 LEU A CB  1 
ATOM   1673  C  CG  . LEU A 1 213 ? 41.729  93.067  66.775  1.00 33.09  ? 213 LEU A CG  1 
ATOM   1674  C  CD1 . LEU A 1 213 ? 42.611  93.926  67.680  1.00 30.62  ? 213 LEU A CD1 1 
ATOM   1675  C  CD2 . LEU A 1 213 ? 42.367  92.862  65.407  1.00 34.94  ? 213 LEU A CD2 1 
ATOM   1676  N  N   . PRO A 1 214 ? 41.642  88.538  66.566  1.00 34.21  ? 214 PRO A N   1 
ATOM   1677  C  CA  . PRO A 1 214 ? 41.806  87.204  67.155  1.00 36.74  ? 214 PRO A CA  1 
ATOM   1678  C  C   . PRO A 1 214 ? 42.123  87.323  68.639  1.00 39.20  ? 214 PRO A C   1 
ATOM   1679  O  O   . PRO A 1 214 ? 42.889  88.198  69.068  1.00 36.48  ? 214 PRO A O   1 
ATOM   1680  C  CB  . PRO A 1 214 ? 42.976  86.589  66.372  1.00 37.93  ? 214 PRO A CB  1 
ATOM   1681  C  CG  . PRO A 1 214 ? 43.342  87.547  65.315  1.00 36.55  ? 214 PRO A CG  1 
ATOM   1682  C  CD  . PRO A 1 214 ? 42.725  88.880  65.632  1.00 35.31  ? 214 PRO A CD  1 
ATOM   1683  N  N   . GLY A 1 215 ? 41.476  86.461  69.432  1.00 41.59  ? 215 GLY A N   1 
ATOM   1684  C  CA  . GLY A 1 215 ? 41.684  86.466  70.869  1.00 39.70  ? 215 GLY A CA  1 
ATOM   1685  C  C   . GLY A 1 215 ? 43.002  85.878  71.312  1.00 39.48  ? 215 GLY A C   1 
ATOM   1686  O  O   . GLY A 1 215 ? 43.397  86.078  72.464  1.00 45.27  ? 215 GLY A O   1 
ATOM   1687  N  N   . PHE A 1 216 ? 43.670  85.125  70.436  1.00 36.72  ? 216 PHE A N   1 
ATOM   1688  C  CA  . PHE A 1 216 ? 45.050  84.711  70.633  1.00 35.48  ? 216 PHE A CA  1 
ATOM   1689  C  C   . PHE A 1 216 ? 45.822  85.084  69.376  1.00 34.82  ? 216 PHE A C   1 
ATOM   1690  O  O   . PHE A 1 216 ? 45.327  84.886  68.262  1.00 30.92  ? 216 PHE A O   1 
ATOM   1691  C  CB  . PHE A 1 216 ? 45.184  83.191  70.925  1.00 31.51  ? 216 PHE A CB  1 
ATOM   1692  C  CG  . PHE A 1 216 ? 46.619  82.718  70.999  1.00 40.02  ? 216 PHE A CG  1 
ATOM   1693  C  CD1 . PHE A 1 216 ? 47.412  82.613  69.844  1.00 36.71  ? 216 PHE A CD1 1 
ATOM   1694  C  CD2 . PHE A 1 216 ? 47.197  82.432  72.229  1.00 36.04  ? 216 PHE A CD2 1 
ATOM   1695  C  CE1 . PHE A 1 216 ? 48.738  82.220  69.913  1.00 38.78  ? 216 PHE A CE1 1 
ATOM   1696  C  CE2 . PHE A 1 216 ? 48.521  82.009  72.307  1.00 37.83  ? 216 PHE A CE2 1 
ATOM   1697  C  CZ  . PHE A 1 216 ? 49.293  81.909  71.149  1.00 37.80  ? 216 PHE A CZ  1 
ATOM   1698  N  N   . LEU A 1 217 ? 47.044  85.595  69.551  1.00 30.95  ? 217 LEU A N   1 
ATOM   1699  C  CA  . LEU A 1 217 ? 47.803  86.053  68.393  1.00 28.21  ? 217 LEU A CA  1 
ATOM   1700  C  C   . LEU A 1 217 ? 49.242  86.370  68.779  1.00 27.62  ? 217 LEU A C   1 
ATOM   1701  O  O   . LEU A 1 217 ? 49.530  86.759  69.913  1.00 31.73  ? 217 LEU A O   1 
ATOM   1702  C  CB  . LEU A 1 217 ? 47.139  87.273  67.749  1.00 26.48  ? 217 LEU A CB  1 
ATOM   1703  C  CG  . LEU A 1 217 ? 47.198  88.652  68.380  1.00 28.95  ? 217 LEU A CG  1 
ATOM   1704  C  CD1 . LEU A 1 217 ? 46.334  89.607  67.547  1.00 26.87  ? 217 LEU A CD1 1 
ATOM   1705  C  CD2 . LEU A 1 217 ? 46.761  88.633  69.839  1.00 31.32  ? 217 LEU A CD2 1 
ATOM   1706  N  N   . ALA A 1 218 ? 50.143  86.163  67.823  1.00 23.17  ? 218 ALA A N   1 
ATOM   1707  C  CA  . ALA A 1 218 ? 51.522  86.582  67.989  1.00 23.23  ? 218 ALA A CA  1 
ATOM   1708  C  C   . ALA A 1 218 ? 51.716  88.054  67.621  1.00 20.53  ? 218 ALA A C   1 
ATOM   1709  O  O   . ALA A 1 218 ? 52.423  88.769  68.327  1.00 20.69  ? 218 ALA A O   1 
ATOM   1710  C  CB  . ALA A 1 218 ? 52.452  85.704  67.143  1.00 22.88  ? 218 ALA A CB  1 
ATOM   1711  N  N   . SER A 1 219 ? 51.097  88.526  66.537  1.00 22.63  ? 219 SER A N   1 
ATOM   1712  C  CA  . SER A 1 219 ? 51.287  89.904  66.095  1.00 21.36  ? 219 SER A CA  1 
ATOM   1713  C  C   . SER A 1 219 ? 49.982  90.441  65.533  1.00 21.36  ? 219 SER A C   1 
ATOM   1714  O  O   . SER A 1 219 ? 49.484  89.921  64.529  1.00 19.34  ? 219 SER A O   1 
ATOM   1715  C  CB  . SER A 1 219 ? 52.394  89.990  65.043  1.00 20.59  ? 219 SER A CB  1 
ATOM   1716  O  OG  . SER A 1 219 ? 52.351  91.238  64.388  1.00 19.35  ? 219 SER A OG  1 
ATOM   1717  N  N   . THR A 1 220 ? 49.429  91.482  66.166  1.00 23.23  ? 220 THR A N   1 
ATOM   1718  C  CA  . THR A 1 220 ? 48.207  92.082  65.624  1.00 22.96  ? 220 THR A CA  1 
ATOM   1719  C  C   . THR A 1 220 ? 48.465  92.764  64.288  1.00 20.95  ? 220 THR A C   1 
ATOM   1720  O  O   . THR A 1 220 ? 47.606  92.736  63.396  1.00 18.39  ? 220 THR A O   1 
ATOM   1721  C  CB  . THR A 1 220 ? 47.615  93.110  66.582  1.00 25.01  ? 220 THR A CB  1 
ATOM   1722  O  OG1 . THR A 1 220 ? 47.539  92.553  67.897  1.00 26.13  ? 220 THR A OG1 1 
ATOM   1723  C  CG2 . THR A 1 220 ? 46.202  93.511  66.089  1.00 23.24  ? 220 THR A CG2 1 
ATOM   1724  N  N   . VAL A 1 221 ? 49.617  93.433  64.162  1.00 18.43  ? 221 VAL A N   1 
ATOM   1725  C  CA  . VAL A 1 221 ? 49.951  94.109  62.911  1.00 20.29  ? 221 VAL A CA  1 
ATOM   1726  C  C   . VAL A 1 221 ? 49.933  93.120  61.749  1.00 20.48  ? 221 VAL A C   1 
ATOM   1727  O  O   . VAL A 1 221 ? 49.306  93.377  60.719  1.00 21.87  ? 221 VAL A O   1 
ATOM   1728  C  CB  . VAL A 1 221 ? 51.302  94.839  63.026  1.00 22.30  ? 221 VAL A CB  1 
ATOM   1729  C  CG1 . VAL A 1 221 ? 51.763  95.337  61.640  1.00 18.23  ? 221 VAL A CG1 1 
ATOM   1730  C  CG2 . VAL A 1 221 ? 51.192  96.009  64.038  1.00 19.52  ? 221 VAL A CG2 1 
ATOM   1731  N  N   . ASP A 1 222 ? 50.588  91.957  61.910  1.00 21.52  ? 222 ASP A N   1 
ATOM   1732  C  CA  . ASP A 1 222 ? 50.603  90.961  60.832  1.00 21.18  ? 222 ASP A CA  1 
ATOM   1733  C  C   . ASP A 1 222 ? 49.213  90.376  60.596  1.00 22.90  ? 222 ASP A C   1 
ATOM   1734  O  O   . ASP A 1 222 ? 48.797  90.189  59.444  1.00 19.61  ? 222 ASP A O   1 
ATOM   1735  C  CB  . ASP A 1 222 ? 51.597  89.833  61.140  1.00 17.62  ? 222 ASP A CB  1 
ATOM   1736  C  CG  . ASP A 1 222 ? 53.055  90.299  61.093  1.00 22.90  ? 222 ASP A CG  1 
ATOM   1737  O  OD1 . ASP A 1 222 ? 53.348  91.268  60.368  1.00 24.66  ? 222 ASP A OD1 1 
ATOM   1738  O  OD2 . ASP A 1 222 ? 53.900  89.703  61.793  1.00 22.03  ? 222 ASP A OD2 1 
ATOM   1739  N  N   . ALA A 1 223 ? 48.484  90.085  61.675  1.00 17.43  ? 223 ALA A N   1 
ATOM   1740  C  CA  . ALA A 1 223 ? 47.191  89.432  61.534  1.00 18.18  ? 223 ALA A CA  1 
ATOM   1741  C  C   . ALA A 1 223 ? 46.246  90.253  60.664  1.00 19.22  ? 223 ALA A C   1 
ATOM   1742  O  O   . ALA A 1 223 ? 45.597  89.710  59.754  1.00 19.69  ? 223 ALA A O   1 
ATOM   1743  C  CB  . ALA A 1 223 ? 46.591  89.167  62.919  1.00 16.61  ? 223 ALA A CB  1 
ATOM   1744  N  N   . VAL A 1 224 ? 46.150  91.570  60.918  1.00 18.12  ? 224 VAL A N   1 
ATOM   1745  C  CA  . VAL A 1 224 ? 45.205  92.378  60.140  1.00 17.69  ? 224 VAL A CA  1 
ATOM   1746  C  C   . VAL A 1 224 ? 45.697  92.577  58.709  1.00 22.43  ? 224 VAL A C   1 
ATOM   1747  O  O   . VAL A 1 224 ? 44.884  92.642  57.773  1.00 20.34  ? 224 VAL A O   1 
ATOM   1748  C  CB  . VAL A 1 224 ? 44.930  93.742  60.789  1.00 21.46  ? 224 VAL A CB  1 
ATOM   1749  C  CG1 . VAL A 1 224 ? 44.220  93.578  62.128  1.00 19.24  ? 224 VAL A CG1 1 
ATOM   1750  C  CG2 . VAL A 1 224 ? 46.224  94.568  60.898  1.00 21.17  ? 224 VAL A CG2 1 
ATOM   1751  N  N   . ARG A 1 225 ? 47.020  92.692  58.508  1.00 16.73  ? 225 ARG A N   1 
ATOM   1752  C  CA  . ARG A 1 225 ? 47.530  92.776  57.142  1.00 21.46  ? 225 ARG A CA  1 
ATOM   1753  C  C   . ARG A 1 225 ? 47.292  91.476  56.395  1.00 17.48  ? 225 ARG A C   1 
ATOM   1754  O  O   . ARG A 1 225 ? 46.932  91.501  55.223  1.00 19.29  ? 225 ARG A O   1 
ATOM   1755  C  CB  . ARG A 1 225 ? 49.017  93.153  57.146  1.00 21.50  ? 225 ARG A CB  1 
ATOM   1756  C  CG  . ARG A 1 225 ? 49.208  94.557  57.706  1.00 20.98  ? 225 ARG A CG  1 
ATOM   1757  C  CD  . ARG A 1 225 ? 50.631  94.986  57.734  1.00 23.07  ? 225 ARG A CD  1 
ATOM   1758  N  NE  . ARG A 1 225 ? 50.757  96.308  58.328  1.00 21.90  ? 225 ARG A NE  1 
ATOM   1759  C  CZ  . ARG A 1 225 ? 51.909  96.928  58.538  1.00 21.84  ? 225 ARG A CZ  1 
ATOM   1760  N  NH1 . ARG A 1 225 ? 53.063  96.371  58.196  1.00 22.83  ? 225 ARG A NH1 1 
ATOM   1761  N  NH2 . ARG A 1 225 ? 51.905  98.113  59.150  1.00 19.53  ? 225 ARG A NH2 1 
ATOM   1762  N  N   . SER A 1 226 ? 47.429  90.339  57.083  1.00 16.91  ? 226 SER A N   1 
ATOM   1763  C  CA  . SER A 1 226 ? 47.154  89.051  56.468  1.00 18.06  ? 226 SER A CA  1 
ATOM   1764  C  C   . SER A 1 226 ? 45.677  88.901  56.104  1.00 19.28  ? 226 SER A C   1 
ATOM   1765  O  O   . SER A 1 226 ? 45.350  88.316  55.064  1.00 18.54  ? 226 SER A O   1 
ATOM   1766  C  CB  . SER A 1 226 ? 47.613  87.924  57.394  1.00 16.69  ? 226 SER A CB  1 
ATOM   1767  O  OG  . SER A 1 226 ? 49.038  87.820  57.392  1.00 17.34  ? 226 SER A OG  1 
ATOM   1768  N  N   . VAL A 1 227 ? 44.766  89.410  56.936  1.00 20.79  ? 227 VAL A N   1 
ATOM   1769  C  CA  . VAL A 1 227 ? 43.361  89.402  56.538  1.00 18.82  ? 227 VAL A CA  1 
ATOM   1770  C  C   . VAL A 1 227 ? 43.182  90.206  55.255  1.00 23.04  ? 227 VAL A C   1 
ATOM   1771  O  O   . VAL A 1 227 ? 42.507  89.765  54.316  1.00 22.38  ? 227 VAL A O   1 
ATOM   1772  C  CB  . VAL A 1 227 ? 42.459  89.933  57.668  1.00 20.82  ? 227 VAL A CB  1 
ATOM   1773  C  CG1 . VAL A 1 227 ? 41.045  90.285  57.107  1.00 21.16  ? 227 VAL A CG1 1 
ATOM   1774  C  CG2 . VAL A 1 227 ? 42.362  88.900  58.825  1.00 19.07  ? 227 VAL A CG2 1 
ATOM   1775  N  N   . ARG A 1 228 ? 43.806  91.389  55.180  1.00 19.60  ? 228 ARG A N   1 
ATOM   1776  C  CA  . ARG A 1 228 ? 43.635  92.185  53.968  1.00 23.97  ? 228 ARG A CA  1 
ATOM   1777  C  C   . ARG A 1 228 ? 44.278  91.506  52.773  1.00 21.44  ? 228 ARG A C   1 
ATOM   1778  O  O   . ARG A 1 228 ? 43.730  91.557  51.668  1.00 19.87  ? 228 ARG A O   1 
ATOM   1779  C  CB  . ARG A 1 228 ? 44.171  93.602  54.160  1.00 23.39  ? 228 ARG A CB  1 
ATOM   1780  C  CG  . ARG A 1 228 ? 43.288  94.364  55.123  1.00 26.20  ? 228 ARG A CG  1 
ATOM   1781  C  CD  . ARG A 1 228 ? 43.367  95.856  54.965  1.00 27.15  ? 228 ARG A CD  1 
ATOM   1782  N  NE  . ARG A 1 228 ? 42.371  96.482  55.827  1.00 29.98  ? 228 ARG A NE  1 
ATOM   1783  C  CZ  . ARG A 1 228 ? 42.197  97.790  55.956  1.00 28.54  ? 228 ARG A CZ  1 
ATOM   1784  N  NH1 . ARG A 1 228 ? 42.957  98.657  55.309  1.00 30.24  ? 228 ARG A NH1 1 
ATOM   1785  N  NH2 . ARG A 1 228 ? 41.237  98.239  56.758  1.00 28.61  ? 228 ARG A NH2 1 
ATOM   1786  N  N   . LYS A 1 229 ? 45.404  90.823  52.980  1.00 18.55  ? 229 LYS A N   1 
ATOM   1787  C  CA  . LYS A 1 229 ? 45.986  90.039  51.892  1.00 23.21  ? 229 LYS A CA  1 
ATOM   1788  C  C   . LYS A 1 229 ? 44.990  88.999  51.376  1.00 22.85  ? 229 LYS A C   1 
ATOM   1789  O  O   . LYS A 1 229 ? 44.839  88.810  50.161  1.00 18.05  ? 229 LYS A O   1 
ATOM   1790  C  CB  . LYS A 1 229 ? 47.272  89.367  52.371  1.00 19.57  ? 229 LYS A CB  1 
ATOM   1791  C  CG  . LYS A 1 229 ? 47.915  88.432  51.356  1.00 22.10  ? 229 LYS A CG  1 
ATOM   1792  C  CD  . LYS A 1 229 ? 49.118  87.732  51.977  1.00 18.05  ? 229 LYS A CD  1 
ATOM   1793  C  CE  . LYS A 1 229 ? 49.867  86.857  50.976  1.00 23.03  ? 229 LYS A CE  1 
ATOM   1794  N  NZ  . LYS A 1 229 ? 51.014  86.205  51.658  1.00 20.16  ? 229 LYS A NZ  1 
ATOM   1795  N  N   . LEU A 1 230 ? 44.253  88.362  52.291  1.00 21.18  ? 230 LEU A N   1 
ATOM   1796  C  CA  . LEU A 1 230 ? 43.243  87.399  51.875  1.00 21.33  ? 230 LEU A CA  1 
ATOM   1797  C  C   . LEU A 1 230 ? 42.078  88.091  51.163  1.00 21.30  ? 230 LEU A C   1 
ATOM   1798  O  O   . LEU A 1 230 ? 41.553  87.561  50.174  1.00 23.71  ? 230 LEU A O   1 
ATOM   1799  C  CB  . LEU A 1 230 ? 42.782  86.590  53.090  1.00 19.69  ? 230 LEU A CB  1 
ATOM   1800  C  CG  . LEU A 1 230 ? 43.810  85.640  53.726  1.00 20.11  ? 230 LEU A CG  1 
ATOM   1801  C  CD1 . LEU A 1 230 ? 43.127  84.738  54.780  1.00 23.07  ? 230 LEU A CD1 1 
ATOM   1802  C  CD2 . LEU A 1 230 ? 44.546  84.766  52.699  1.00 16.13  ? 230 LEU A CD2 1 
ATOM   1803  N  N   . HIS A 1 231 ? 41.689  89.288  51.622  1.00 21.26  ? 231 HIS A N   1 
ATOM   1804  C  CA  . HIS A 1 231 ? 40.673  90.084  50.925  1.00 20.92  ? 231 HIS A CA  1 
ATOM   1805  C  C   . HIS A 1 231 ? 41.028  90.242  49.456  1.00 25.71  ? 231 HIS A C   1 
ATOM   1806  O  O   . HIS A 1 231 ? 40.202  89.986  48.572  1.00 25.95  ? 231 HIS A O   1 
ATOM   1807  C  CB  . HIS A 1 231 ? 40.539  91.481  51.546  1.00 23.40  ? 231 HIS A CB  1 
ATOM   1808  C  CG  . HIS A 1 231 ? 39.893  91.509  52.899  1.00 26.59  ? 231 HIS A CG  1 
ATOM   1809  N  ND1 . HIS A 1 231 ? 39.850  92.651  53.676  1.00 24.86  ? 231 HIS A ND1 1 
ATOM   1810  C  CD2 . HIS A 1 231 ? 39.261  90.545  53.613  1.00 24.78  ? 231 HIS A CD2 1 
ATOM   1811  C  CE1 . HIS A 1 231 ? 39.226  92.388  54.810  1.00 24.82  ? 231 HIS A CE1 1 
ATOM   1812  N  NE2 . HIS A 1 231 ? 38.862  91.117  54.800  1.00 25.18  ? 231 HIS A NE2 1 
ATOM   1813  N  N   . ALA A 1 232 ? 42.268  90.672  49.179  1.00 23.16  ? 232 ALA A N   1 
ATOM   1814  C  CA  . ALA A 1 232 ? 42.700  90.843  47.796  1.00 22.81  ? 232 ALA A CA  1 
ATOM   1815  C  C   . ALA A 1 232 ? 42.696  89.513  47.058  1.00 20.22  ? 232 ALA A C   1 
ATOM   1816  O  O   . ALA A 1 232 ? 42.337  89.446  45.872  1.00 21.35  ? 232 ALA A O   1 
ATOM   1817  C  CB  . ALA A 1 232 ? 44.097  91.487  47.751  1.00 20.76  ? 232 ALA A CB  1 
ATOM   1818  N  N   . LEU A 1 233 ? 43.108  88.443  47.739  1.00 20.49  ? 233 LEU A N   1 
ATOM   1819  C  CA  . LEU A 1 233 ? 43.134  87.133  47.105  1.00 20.20  ? 233 LEU A CA  1 
ATOM   1820  C  C   . LEU A 1 233 ? 41.715  86.635  46.822  1.00 22.06  ? 233 LEU A C   1 
ATOM   1821  O  O   . LEU A 1 233 ? 41.436  86.141  45.728  1.00 20.71  ? 233 LEU A O   1 
ATOM   1822  C  CB  . LEU A 1 233 ? 43.914  86.143  47.975  1.00 21.05  ? 233 LEU A CB  1 
ATOM   1823  C  CG  . LEU A 1 233 ? 44.082  84.717  47.421  1.00 24.00  ? 233 LEU A CG  1 
ATOM   1824  C  CD1 . LEU A 1 233 ? 44.863  84.714  46.088  1.00 19.10  ? 233 LEU A CD1 1 
ATOM   1825  C  CD2 . LEU A 1 233 ? 44.758  83.792  48.446  1.00 23.75  ? 233 LEU A CD2 1 
ATOM   1826  N  N   . ALA A 1 234 ? 40.793  86.798  47.777  1.00 22.25  ? 234 ALA A N   1 
ATOM   1827  C  CA  . ALA A 1 234 ? 39.410  86.404  47.521  1.00 25.31  ? 234 ALA A CA  1 
ATOM   1828  C  C   . ALA A 1 234 ? 38.802  87.194  46.363  1.00 23.14  ? 234 ALA A C   1 
ATOM   1829  O  O   . ALA A 1 234 ? 38.063  86.637  45.549  1.00 23.45  ? 234 ALA A O   1 
ATOM   1830  C  CB  . ALA A 1 234 ? 38.562  86.580  48.785  1.00 20.82  ? 234 ALA A CB  1 
ATOM   1831  N  N   . GLU A 1 235 ? 39.082  88.495  46.285  1.00 21.73  ? 235 GLU A N   1 
ATOM   1832  C  CA  . GLU A 1 235 ? 38.490  89.300  45.225  1.00 22.10  ? 235 GLU A CA  1 
ATOM   1833  C  C   . GLU A 1 235 ? 39.086  88.960  43.868  1.00 23.33  ? 235 GLU A C   1 
ATOM   1834  O  O   . GLU A 1 235 ? 38.384  89.028  42.859  1.00 25.43  ? 235 GLU A O   1 
ATOM   1835  C  CB  . GLU A 1 235 ? 38.677  90.791  45.515  1.00 22.58  ? 235 GLU A CB  1 
ATOM   1836  C  CG  . GLU A 1 235 ? 37.892  91.721  44.569  1.00 23.62  ? 235 GLU A CG  1 
ATOM   1837  C  CD  . GLU A 1 235 ? 38.655  92.015  43.284  1.00 27.47  ? 235 GLU A CD  1 
ATOM   1838  O  OE1 . GLU A 1 235 ? 39.860  91.699  43.236  1.00 23.68  ? 235 GLU A OE1 1 
ATOM   1839  O  OE2 . GLU A 1 235 ? 38.066  92.584  42.336  1.00 27.93  ? 235 GLU A OE2 1 
ATOM   1840  N  N   . LYS A 1 236 ? 40.377  88.625  43.819  1.00 21.90  ? 236 LYS A N   1 
ATOM   1841  C  CA  . LYS A 1 236 ? 41.026  88.286  42.544  1.00 23.83  ? 236 LYS A CA  1 
ATOM   1842  C  C   . LYS A 1 236 ? 40.471  86.990  41.974  1.00 26.75  ? 236 LYS A C   1 
ATOM   1843  O  O   . LYS A 1 236 ? 40.201  86.891  40.770  1.00 28.00  ? 236 LYS A O   1 
ATOM   1844  C  CB  . LYS A 1 236 ? 42.543  88.158  42.747  1.00 19.78  ? 236 LYS A CB  1 
ATOM   1845  C  CG  . LYS A 1 236 ? 43.324  87.462  41.611  1.00 28.03  ? 236 LYS A CG  1 
ATOM   1846  C  CD  . LYS A 1 236 ? 44.864  87.588  41.819  1.00 19.89  ? 236 LYS A CD  1 
ATOM   1847  C  CE  . LYS A 1 236 ? 45.687  86.609  40.926  1.00 24.14  ? 236 LYS A CE  1 
ATOM   1848  N  NZ  . LYS A 1 236 ? 47.192  86.750  41.163  1.00 25.10  ? 236 LYS A NZ  1 
ATOM   1849  N  N   . THR A 1 237 ? 40.313  85.981  42.826  1.00 23.96  ? 237 THR A N   1 
ATOM   1850  C  CA  . THR A 1 237 ? 40.003  84.634  42.386  1.00 25.29  ? 237 THR A CA  1 
ATOM   1851  C  C   . THR A 1 237 ? 38.512  84.307  42.443  1.00 24.29  ? 237 THR A C   1 
ATOM   1852  O  O   . THR A 1 237 ? 38.087  83.351  41.793  1.00 26.08  ? 237 THR A O   1 
ATOM   1853  C  CB  . THR A 1 237 ? 40.769  83.610  43.241  1.00 25.58  ? 237 THR A CB  1 
ATOM   1854  O  OG1 . THR A 1 237 ? 40.276  83.657  44.592  1.00 27.28  ? 237 THR A OG1 1 
ATOM   1855  C  CG2 . THR A 1 237 ? 42.259  83.901  43.240  1.00 20.19  ? 237 THR A CG2 1 
ATOM   1856  N  N   . GLY A 1 238 ? 37.718  85.056  43.207  1.00 23.51  ? 238 GLY A N   1 
ATOM   1857  C  CA  . GLY A 1 238 ? 36.339  84.662  43.440  1.00 23.56  ? 238 GLY A CA  1 
ATOM   1858  C  C   . GLY A 1 238 ? 36.194  83.451  44.337  1.00 30.25  ? 238 GLY A C   1 
ATOM   1859  O  O   . GLY A 1 238 ? 35.169  82.759  44.283  1.00 31.53  ? 238 GLY A O   1 
ATOM   1860  N  N   . ALA A 1 239 ? 37.197  83.168  45.166  1.00 28.87  ? 239 ALA A N   1 
ATOM   1861  C  CA  . ALA A 1 239 ? 37.217  81.914  45.905  1.00 27.37  ? 239 ALA A CA  1 
ATOM   1862  C  C   . ALA A 1 239 ? 36.070  81.850  46.905  1.00 27.98  ? 239 ALA A C   1 
ATOM   1863  O  O   . ALA A 1 239 ? 35.561  82.873  47.382  1.00 29.75  ? 239 ALA A O   1 
ATOM   1864  C  CB  . ALA A 1 239 ? 38.552  81.732  46.627  1.00 23.89  ? 239 ALA A CB  1 
ATOM   1865  N  N   . LEU A 1 240 ? 35.638  80.630  47.184  1.00 26.60  ? 240 LEU A N   1 
ATOM   1866  C  CA  . LEU A 1 240 ? 34.780  80.393  48.331  1.00 27.17  ? 240 LEU A CA  1 
ATOM   1867  C  C   . LEU A 1 240 ? 35.641  80.473  49.584  1.00 28.48  ? 240 LEU A C   1 
ATOM   1868  O  O   . LEU A 1 240 ? 36.675  79.799  49.680  1.00 24.07  ? 240 LEU A O   1 
ATOM   1869  C  CB  . LEU A 1 240 ? 34.114  79.018  48.213  1.00 28.23  ? 240 LEU A CB  1 
ATOM   1870  C  CG  . LEU A 1 240 ? 33.437  78.382  49.418  1.00 27.11  ? 240 LEU A CG  1 
ATOM   1871  C  CD1 . LEU A 1 240 ? 32.150  79.125  49.695  1.00 26.83  ? 240 LEU A CD1 1 
ATOM   1872  C  CD2 . LEU A 1 240 ? 33.142  76.887  49.148  1.00 25.03  ? 240 LEU A CD2 1 
ATOM   1873  N  N   . VAL A 1 241 ? 35.239  81.314  50.536  1.00 24.63  ? 241 VAL A N   1 
ATOM   1874  C  CA  . VAL A 1 241 ? 36.052  81.566  51.717  1.00 24.76  ? 241 VAL A CA  1 
ATOM   1875  C  C   . VAL A 1 241 ? 35.544  80.690  52.853  1.00 29.20  ? 241 VAL A C   1 
ATOM   1876  O  O   . VAL A 1 241 ? 34.355  80.731  53.198  1.00 26.59  ? 241 VAL A O   1 
ATOM   1877  C  CB  . VAL A 1 241 ? 36.039  83.050  52.105  1.00 26.84  ? 241 VAL A CB  1 
ATOM   1878  C  CG1 . VAL A 1 241 ? 36.930  83.274  53.324  1.00 24.74  ? 241 VAL A CG1 1 
ATOM   1879  C  CG2 . VAL A 1 241 ? 36.501  83.915  50.914  1.00 25.67  ? 241 VAL A CG2 1 
ATOM   1880  N  N   . VAL A 1 242 ? 36.446  79.902  53.443  1.00 28.10  ? 242 VAL A N   1 
ATOM   1881  C  CA  . VAL A 1 242 ? 36.118  79.028  54.568  1.00 29.51  ? 242 VAL A CA  1 
ATOM   1882  C  C   . VAL A 1 242 ? 36.820  79.571  55.806  1.00 26.50  ? 242 VAL A C   1 
ATOM   1883  O  O   . VAL A 1 242 ? 38.050  79.517  55.898  1.00 28.93  ? 242 VAL A O   1 
ATOM   1884  C  CB  . VAL A 1 242 ? 36.522  77.575  54.287  1.00 29.02  ? 242 VAL A CB  1 
ATOM   1885  C  CG1 . VAL A 1 242 ? 36.143  76.666  55.454  1.00 31.76  ? 242 VAL A CG1 1 
ATOM   1886  C  CG2 . VAL A 1 242 ? 35.896  77.112  53.006  1.00 25.33  ? 242 VAL A CG2 1 
ATOM   1887  N  N   . TYR A 1 243 ? 36.049  80.070  56.768  1.00 25.62  ? 243 TYR A N   1 
ATOM   1888  C  CA  . TYR A 1 243 ? 36.608  80.617  57.996  1.00 28.44  ? 243 TYR A CA  1 
ATOM   1889  C  C   . TYR A 1 243 ? 37.084  79.505  58.928  1.00 29.73  ? 243 TYR A C   1 
ATOM   1890  O  O   . TYR A 1 243 ? 36.578  78.380  58.905  1.00 30.24  ? 243 TYR A O   1 
ATOM   1891  C  CB  . TYR A 1 243 ? 35.577  81.515  58.686  1.00 29.05  ? 243 TYR A CB  1 
ATOM   1892  C  CG  . TYR A 1 243 ? 34.998  82.497  57.708  1.00 28.87  ? 243 TYR A CG  1 
ATOM   1893  C  CD1 . TYR A 1 243 ? 35.676  83.669  57.395  1.00 27.90  ? 243 TYR A CD1 1 
ATOM   1894  C  CD2 . TYR A 1 243 ? 33.801  82.230  57.046  1.00 31.10  ? 243 TYR A CD2 1 
ATOM   1895  C  CE1 . TYR A 1 243 ? 35.171  84.559  56.462  1.00 30.97  ? 243 TYR A CE1 1 
ATOM   1896  C  CE2 . TYR A 1 243 ? 33.287  83.114  56.103  1.00 30.29  ? 243 TYR A CE2 1 
ATOM   1897  C  CZ  . TYR A 1 243 ? 33.975  84.278  55.820  1.00 35.92  ? 243 TYR A CZ  1 
ATOM   1898  O  OH  . TYR A 1 243 ? 33.465  85.167  54.893  1.00 38.86  ? 243 TYR A OH  1 
ATOM   1899  N  N   . GLY A 1 244 ? 38.079  79.831  59.760  1.00 29.19  ? 244 GLY A N   1 
ATOM   1900  C  CA  . GLY A 1 244 ? 38.801  78.790  60.477  1.00 27.38  ? 244 GLY A CA  1 
ATOM   1901  C  C   . GLY A 1 244 ? 38.012  78.122  61.589  1.00 34.74  ? 244 GLY A C   1 
ATOM   1902  O  O   . GLY A 1 244 ? 38.178  76.922  61.829  1.00 33.90  ? 244 GLY A O   1 
ATOM   1903  N  N   . HIS A 1 245 ? 37.171  78.880  62.290  1.00 29.76  ? 245 HIS A N   1 
ATOM   1904  C  CA  . HIS A 1 245 ? 36.543  78.415  63.525  1.00 33.36  ? 245 HIS A CA  1 
ATOM   1905  C  C   . HIS A 1 245 ? 35.207  79.130  63.723  1.00 35.39  ? 245 HIS A C   1 
ATOM   1906  O  O   . HIS A 1 245 ? 34.953  79.717  64.772  1.00 37.01  ? 245 HIS A O   1 
ATOM   1907  C  CB  . HIS A 1 245 ? 37.443  78.676  64.735  1.00 31.65  ? 245 HIS A CB  1 
ATOM   1908  C  CG  . HIS A 1 245 ? 38.609  77.744  64.867  1.00 36.62  ? 245 HIS A CG  1 
ATOM   1909  N  ND1 . HIS A 1 245 ? 38.466  76.381  65.003  1.00 35.47  ? 245 HIS A ND1 1 
ATOM   1910  C  CD2 . HIS A 1 245 ? 39.943  77.989  64.928  1.00 35.21  ? 245 HIS A CD2 1 
ATOM   1911  C  CE1 . HIS A 1 245 ? 39.660  75.823  65.129  1.00 36.16  ? 245 HIS A CE1 1 
ATOM   1912  N  NE2 . HIS A 1 245 ? 40.573  76.779  65.089  1.00 32.86  ? 245 HIS A NE2 1 
ATOM   1913  N  N   . ASP A 1 246 ? 34.341  79.126  62.706  1.00 35.91  ? 246 ASP A N   1 
ATOM   1914  C  CA  . ASP A 1 246 ? 33.115  79.923  62.749  1.00 33.97  ? 246 ASP A CA  1 
ATOM   1915  C  C   . ASP A 1 246 ? 31.922  79.011  62.987  1.00 38.92  ? 246 ASP A C   1 
ATOM   1916  O  O   . ASP A 1 246 ? 31.463  78.332  62.052  1.00 36.37  ? 246 ASP A O   1 
ATOM   1917  C  CB  . ASP A 1 246 ? 32.922  80.720  61.456  1.00 35.29  ? 246 ASP A CB  1 
ATOM   1918  C  CG  . ASP A 1 246 ? 31.855  81.825  61.587  1.00 40.71  ? 246 ASP A CG  1 
ATOM   1919  O  OD1 . ASP A 1 246 ? 30.807  81.619  62.253  1.00 40.05  ? 246 ASP A OD1 1 
ATOM   1920  O  OD2 . ASP A 1 246 ? 32.065  82.904  60.996  1.00 41.32  ? 246 ASP A OD2 1 
ATOM   1921  N  N   . PRO A 1 247 ? 31.366  78.974  64.203  1.00 42.28  ? 247 PRO A N   1 
ATOM   1922  C  CA  . PRO A 1 247 ? 30.274  78.030  64.475  1.00 42.07  ? 247 PRO A CA  1 
ATOM   1923  C  C   . PRO A 1 247 ? 28.974  78.418  63.796  1.00 43.97  ? 247 PRO A C   1 
ATOM   1924  O  O   . PRO A 1 247 ? 28.069  77.580  63.724  1.00 47.16  ? 247 PRO A O   1 
ATOM   1925  C  CB  . PRO A 1 247 ? 30.144  78.058  66.005  1.00 35.83  ? 247 PRO A CB  1 
ATOM   1926  C  CG  . PRO A 1 247 ? 30.765  79.369  66.442  1.00 33.93  ? 247 PRO A CG  1 
ATOM   1927  C  CD  . PRO A 1 247 ? 31.586  79.927  65.310  1.00 38.93  ? 247 PRO A CD  1 
ATOM   1928  N  N   . GLU A 1 248 ? 28.855  79.643  63.277  1.00 40.59  ? 248 GLU A N   1 
ATOM   1929  C  CA  . GLU A 1 248 ? 27.658  79.986  62.522  1.00 43.03  ? 248 GLU A CA  1 
ATOM   1930  C  C   . GLU A 1 248 ? 27.812  79.665  61.044  1.00 43.95  ? 248 GLU A C   1 
ATOM   1931  O  O   . GLU A 1 248 ? 26.862  79.197  60.406  1.00 43.43  ? 248 GLU A O   1 
ATOM   1932  C  CB  . GLU A 1 248 ? 27.313  81.464  62.716  1.00 44.35  ? 248 GLU A CB  1 
ATOM   1933  C  CG  . GLU A 1 248 ? 26.944  81.797  64.152  1.00 52.94  ? 248 GLU A CG  1 
ATOM   1934  C  CD  . GLU A 1 248 ? 26.520  83.241  64.330  1.00 66.49  ? 248 GLU A CD  1 
ATOM   1935  O  OE1 . GLU A 1 248 ? 25.561  83.489  65.095  1.00 70.69  ? 248 GLU A OE1 1 
ATOM   1936  O  OE2 . GLU A 1 248 ? 27.145  84.126  63.699  1.00 66.39  ? 248 GLU A OE2 1 
ATOM   1937  N  N   . ALA A 1 249 ? 28.997  79.867  60.488  1.00 38.24  ? 249 ALA A N   1 
ATOM   1938  C  CA  . ALA A 1 249 ? 29.184  79.565  59.079  1.00 37.45  ? 249 ALA A CA  1 
ATOM   1939  C  C   . ALA A 1 249 ? 29.570  78.109  58.824  1.00 39.86  ? 249 ALA A C   1 
ATOM   1940  O  O   . ALA A 1 249 ? 29.299  77.595  57.728  1.00 38.37  ? 249 ALA A O   1 
ATOM   1941  C  CB  . ALA A 1 249 ? 30.233  80.505  58.478  1.00 32.47  ? 249 ALA A CB  1 
ATOM   1942  N  N   . TRP A 1 250 ? 30.183  77.429  59.806  1.00 37.50  ? 250 TRP A N   1 
ATOM   1943  C  CA  . TRP A 1 250 ? 30.656  76.061  59.574  1.00 37.90  ? 250 TRP A CA  1 
ATOM   1944  C  C   . TRP A 1 250 ? 29.551  75.137  59.080  1.00 38.96  ? 250 TRP A C   1 
ATOM   1945  O  O   . TRP A 1 250 ? 29.780  74.415  58.093  1.00 39.58  ? 250 TRP A O   1 
ATOM   1946  C  CB  . TRP A 1 250 ? 31.321  75.495  60.839  1.00 33.63  ? 250 TRP A CB  1 
ATOM   1947  C  CG  . TRP A 1 250 ? 31.954  74.136  60.638  1.00 36.56  ? 250 TRP A CG  1 
ATOM   1948  C  CD1 . TRP A 1 250 ? 31.643  72.971  61.295  1.00 36.52  ? 250 TRP A CD1 1 
ATOM   1949  C  CD2 . TRP A 1 250 ? 33.015  73.805  59.723  1.00 34.87  ? 250 TRP A CD2 1 
ATOM   1950  N  NE1 . TRP A 1 250 ? 32.444  71.939  60.842  1.00 35.00  ? 250 TRP A NE1 1 
ATOM   1951  C  CE2 . TRP A 1 250 ? 33.293  72.427  59.880  1.00 35.92  ? 250 TRP A CE2 1 
ATOM   1952  C  CE3 . TRP A 1 250 ? 33.761  74.543  58.792  1.00 37.93  ? 250 TRP A CE3 1 
ATOM   1953  C  CZ2 . TRP A 1 250 ? 34.286  71.773  59.138  1.00 36.32  ? 250 TRP A CZ2 1 
ATOM   1954  C  CZ3 . TRP A 1 250 ? 34.747  73.884  58.049  1.00 37.54  ? 250 TRP A CZ3 1 
ATOM   1955  C  CH2 . TRP A 1 250 ? 34.994  72.516  58.227  1.00 35.30  ? 250 TRP A CH2 1 
ATOM   1956  N  N   . PRO A 1 251 ? 28.353  75.110  59.682  1.00 42.11  ? 251 PRO A N   1 
ATOM   1957  C  CA  . PRO A 1 251 ? 27.283  74.245  59.145  1.00 37.12  ? 251 PRO A CA  1 
ATOM   1958  C  C   . PRO A 1 251 ? 26.859  74.568  57.719  1.00 40.30  ? 251 PRO A C   1 
ATOM   1959  O  O   . PRO A 1 251 ? 26.299  73.687  57.057  1.00 42.82  ? 251 PRO A O   1 
ATOM   1960  C  CB  . PRO A 1 251 ? 26.127  74.471  60.131  1.00 39.99  ? 251 PRO A CB  1 
ATOM   1961  C  CG  . PRO A 1 251 ? 26.818  74.828  61.420  1.00 40.78  ? 251 PRO A CG  1 
ATOM   1962  C  CD  . PRO A 1 251 ? 27.967  75.696  60.987  1.00 40.06  ? 251 PRO A CD  1 
ATOM   1963  N  N   . THR A 1 252 ? 27.101  75.784  57.209  1.00 40.21  ? 252 THR A N   1 
ATOM   1964  C  CA  . THR A 1 252 ? 26.660  76.092  55.848  1.00 38.66  ? 252 THR A CA  1 
ATOM   1965  C  C   . THR A 1 252 ? 27.534  75.481  54.760  1.00 39.88  ? 252 THR A C   1 
ATOM   1966  O  O   . THR A 1 252 ? 27.135  75.522  53.592  1.00 43.32  ? 252 THR A O   1 
ATOM   1967  C  CB  . THR A 1 252 ? 26.589  77.604  55.602  1.00 39.80  ? 252 THR A CB  1 
ATOM   1968  O  OG1 . THR A 1 252 ? 27.890  78.101  55.250  1.00 42.42  ? 252 THR A OG1 1 
ATOM   1969  C  CG2 . THR A 1 252 ? 26.075  78.323  56.820  1.00 39.57  ? 252 THR A CG2 1 
ATOM   1970  N  N   . PHE A 1 253 ? 28.705  74.941  55.092  1.00 38.64  ? 253 PHE A N   1 
ATOM   1971  C  CA  . PHE A 1 253 ? 29.564  74.325  54.092  1.00 40.70  ? 253 PHE A CA  1 
ATOM   1972  C  C   . PHE A 1 253 ? 29.260  72.833  53.951  1.00 43.75  ? 253 PHE A C   1 
ATOM   1973  O  O   . PHE A 1 253 ? 28.503  72.243  54.728  1.00 41.65  ? 253 PHE A O   1 
ATOM   1974  C  CB  . PHE A 1 253 ? 31.041  74.520  54.452  1.00 43.57  ? 253 PHE A CB  1 
ATOM   1975  C  CG  . PHE A 1 253 ? 31.459  75.958  54.560  1.00 42.74  ? 253 PHE A CG  1 
ATOM   1976  C  CD1 . PHE A 1 253 ? 31.665  76.720  53.423  1.00 38.19  ? 253 PHE A CD1 1 
ATOM   1977  C  CD2 . PHE A 1 253 ? 31.635  76.548  55.802  1.00 37.81  ? 253 PHE A CD2 1 
ATOM   1978  C  CE1 . PHE A 1 253 ? 32.035  78.057  53.523  1.00 37.35  ? 253 PHE A CE1 1 
ATOM   1979  C  CE2 . PHE A 1 253 ? 32.015  77.875  55.907  1.00 39.78  ? 253 PHE A CE2 1 
ATOM   1980  C  CZ  . PHE A 1 253 ? 32.207  78.632  54.765  1.00 35.22  ? 253 PHE A CZ  1 
ATOM   1981  N  N   . ARG A 1 254 ? 29.908  72.215  52.959  1.00 43.42  ? 254 ARG A N   1 
ATOM   1982  C  CA  . ARG A 1 254 ? 29.778  70.780  52.704  1.00 44.11  ? 254 ARG A CA  1 
ATOM   1983  C  C   . ARG A 1 254 ? 30.746  70.009  53.605  1.00 46.20  ? 254 ARG A C   1 
ATOM   1984  O  O   . ARG A 1 254 ? 31.968  70.073  53.417  1.00 43.99  ? 254 ARG A O   1 
ATOM   1985  C  CB  . ARG A 1 254 ? 30.022  70.479  51.224  1.00 48.41  ? 254 ARG A CB  1 
ATOM   1986  C  CG  . ARG A 1 254 ? 29.142  71.303  50.293  1.00 46.74  ? 254 ARG A CG  1 
ATOM   1987  C  CD  . ARG A 1 254 ? 29.268  70.919  48.820  1.00 53.40  ? 254 ARG A CD  1 
ATOM   1988  N  NE  . ARG A 1 254 ? 27.941  70.852  48.219  1.00 69.33  ? 254 ARG A NE  1 
ATOM   1989  C  CZ  . ARG A 1 254 ? 27.118  69.816  48.333  1.00 70.88  ? 254 ARG A CZ  1 
ATOM   1990  N  NH1 . ARG A 1 254 ? 27.520  68.667  48.856  1.00 68.40  ? 254 ARG A NH1 1 
ATOM   1991  N  NH2 . ARG A 1 254 ? 25.864  69.932  47.902  1.00 68.28  ? 254 ARG A NH2 1 
ATOM   1992  N  N   . LEU A 1 255 ? 30.199  69.262  54.566  1.00 45.18  ? 255 LEU A N   1 
ATOM   1993  C  CA  . LEU A 1 255 ? 31.017  68.655  55.612  1.00 46.07  ? 255 LEU A CA  1 
ATOM   1994  C  C   . LEU A 1 255 ? 31.152  67.131  55.532  1.00 44.62  ? 255 LEU A C   1 
ATOM   1995  O  O   . LEU A 1 255 ? 30.881  66.498  54.509  1.00 46.69  ? 255 LEU A O   1 
ATOM   1996  C  CB  . LEU A 1 255 ? 30.454  69.038  56.987  1.00 42.42  ? 255 LEU A CB  1 
ATOM   1997  C  CG  . LEU A 1 255 ? 30.364  70.561  57.259  1.00 44.40  ? 255 LEU A CG  1 
ATOM   1998  C  CD1 . LEU A 1 255 ? 30.044  70.870  58.705  1.00 38.21  ? 255 LEU A CD1 1 
ATOM   1999  C  CD2 . LEU A 1 255 ? 31.652  71.285  56.833  1.00 42.63  ? 255 LEU A CD2 1 
ATOM   2000  N  N   . PRO B 1 4   ? 86.972  91.997  92.197  1.00 34.59  ? 4   PRO B N   1 
ATOM   2001  C  CA  . PRO B 1 4   ? 86.668  90.834  91.354  1.00 35.05  ? 4   PRO B CA  1 
ATOM   2002  C  C   . PRO B 1 4   ? 87.875  89.999  90.960  1.00 31.72  ? 4   PRO B C   1 
ATOM   2003  O  O   . PRO B 1 4   ? 88.955  90.528  90.666  1.00 28.52  ? 4   PRO B O   1 
ATOM   2004  C  CB  . PRO B 1 4   ? 86.050  91.452  90.087  1.00 39.30  ? 4   PRO B CB  1 
ATOM   2005  C  CG  . PRO B 1 4   ? 85.747  92.864  90.441  1.00 38.80  ? 4   PRO B CG  1 
ATOM   2006  C  CD  . PRO B 1 4   ? 86.735  93.255  91.473  1.00 38.59  ? 4   PRO B CD  1 
ATOM   2007  N  N   . ARG B 1 5   ? 87.671  88.691  90.913  1.00 31.30  ? 5   ARG B N   1 
ATOM   2008  C  CA  . ARG B 1 5   ? 88.700  87.765  90.473  1.00 32.74  ? 5   ARG B CA  1 
ATOM   2009  C  C   . ARG B 1 5   ? 88.134  86.833  89.413  1.00 33.34  ? 5   ARG B C   1 
ATOM   2010  O  O   . ARG B 1 5   ? 86.937  86.529  89.395  1.00 32.56  ? 5   ARG B O   1 
ATOM   2011  C  CB  . ARG B 1 5   ? 89.236  86.942  91.652  1.00 34.09  ? 5   ARG B CB  1 
ATOM   2012  C  CG  . ARG B 1 5   ? 90.191  87.719  92.546  1.00 33.47  ? 5   ARG B CG  1 
ATOM   2013  C  CD  . ARG B 1 5   ? 90.461  86.953  93.808  1.00 36.33  ? 5   ARG B CD  1 
ATOM   2014  N  NE  . ARG B 1 5   ? 91.432  87.621  94.664  1.00 37.26  ? 5   ARG B NE  1 
ATOM   2015  C  CZ  . ARG B 1 5   ? 92.086  87.004  95.639  1.00 43.33  ? 5   ARG B CZ  1 
ATOM   2016  N  NH1 . ARG B 1 5   ? 91.866  85.727  95.911  1.00 39.78  ? 5   ARG B NH1 1 
ATOM   2017  N  NH2 . ARG B 1 5   ? 92.980  87.681  96.356  1.00 39.51  ? 5   ARG B NH2 1 
ATOM   2018  N  N   . LEU B 1 6   ? 89.008  86.384  88.526  1.00 30.88  ? 6   LEU B N   1 
ATOM   2019  C  CA  . LEU B 1 6   ? 88.697  85.310  87.600  1.00 30.59  ? 6   LEU B CA  1 
ATOM   2020  C  C   . LEU B 1 6   ? 89.429  84.059  88.065  1.00 32.32  ? 6   LEU B C   1 
ATOM   2021  O  O   . LEU B 1 6   ? 90.629  84.115  88.356  1.00 32.38  ? 6   LEU B O   1 
ATOM   2022  C  CB  . LEU B 1 6   ? 89.122  85.680  86.180  1.00 29.75  ? 6   LEU B CB  1 
ATOM   2023  C  CG  . LEU B 1 6   ? 89.139  84.553  85.157  1.00 27.60  ? 6   LEU B CG  1 
ATOM   2024  C  CD1 . LEU B 1 6   ? 87.703  84.102  84.885  1.00 26.87  ? 6   LEU B CD1 1 
ATOM   2025  C  CD2 . LEU B 1 6   ? 89.814  85.028  83.891  1.00 26.84  ? 6   LEU B CD2 1 
ATOM   2026  N  N   . TYR B 1 7   ? 88.704  82.945  88.153  1.00 30.68  ? 7   TYR B N   1 
ATOM   2027  C  CA  . TYR B 1 7   ? 89.281  81.621  88.360  1.00 32.19  ? 7   TYR B CA  1 
ATOM   2028  C  C   . TYR B 1 7   ? 88.923  80.726  87.179  1.00 33.48  ? 7   TYR B C   1 
ATOM   2029  O  O   . TYR B 1 7   ? 87.738  80.571  86.853  1.00 33.77  ? 7   TYR B O   1 
ATOM   2030  C  CB  . TYR B 1 7   ? 88.773  80.966  89.647  1.00 34.27  ? 7   TYR B CB  1 
ATOM   2031  C  CG  . TYR B 1 7   ? 89.115  81.682  90.936  1.00 32.84  ? 7   TYR B CG  1 
ATOM   2032  C  CD1 . TYR B 1 7   ? 88.375  82.782  91.361  1.00 33.61  ? 7   TYR B CD1 1 
ATOM   2033  C  CD2 . TYR B 1 7   ? 90.153  81.235  91.750  1.00 35.72  ? 7   TYR B CD2 1 
ATOM   2034  C  CE1 . TYR B 1 7   ? 88.671  83.433  92.546  1.00 36.25  ? 7   TYR B CE1 1 
ATOM   2035  C  CE2 . TYR B 1 7   ? 90.454  81.874  92.945  1.00 35.30  ? 7   TYR B CE2 1 
ATOM   2036  C  CZ  . TYR B 1 7   ? 89.710  82.967  93.339  1.00 39.83  ? 7   TYR B CZ  1 
ATOM   2037  O  OH  . TYR B 1 7   ? 90.011  83.604  94.521  1.00 40.73  ? 7   TYR B OH  1 
ATOM   2038  N  N   . MET B 1 8   ? 89.939  80.100  86.571  1.00 29.33  ? 8   MET B N   1 
ATOM   2039  C  CA  . MET B 1 8   ? 89.753  79.239  85.404  1.00 32.61  ? 8   MET B CA  1 
ATOM   2040  C  C   . MET B 1 8   ? 89.776  77.781  85.853  1.00 36.94  ? 8   MET B C   1 
ATOM   2041  O  O   . MET B 1 8   ? 90.820  77.272  86.274  1.00 37.60  ? 8   MET B O   1 
ATOM   2042  C  CB  . MET B 1 8   ? 90.830  79.500  84.357  1.00 28.75  ? 8   MET B CB  1 
ATOM   2043  C  CG  . MET B 1 8   ? 91.186  80.957  84.194  1.00 28.62  ? 8   MET B CG  1 
ATOM   2044  S  SD  . MET B 1 8   ? 91.327  81.464  82.476  1.00 40.02  ? 8   MET B SD  1 
ATOM   2045  C  CE  . MET B 1 8   ? 92.838  80.578  82.079  1.00 29.72  ? 8   MET B CE  1 
ATOM   2046  N  N   . PHE B 1 9   ? 88.624  77.114  85.754  1.00 35.96  ? 9   PHE B N   1 
ATOM   2047  C  CA  . PHE B 1 9   ? 88.471  75.708  86.081  1.00 31.34  ? 9   PHE B CA  1 
ATOM   2048  C  C   . PHE B 1 9   ? 88.462  74.868  84.800  1.00 35.75  ? 9   PHE B C   1 
ATOM   2049  O  O   . PHE B 1 9   ? 88.577  75.377  83.678  1.00 32.77  ? 9   PHE B O   1 
ATOM   2050  C  CB  . PHE B 1 9   ? 87.174  75.485  86.862  1.00 36.81  ? 9   PHE B CB  1 
ATOM   2051  C  CG  . PHE B 1 9   ? 87.172  76.048  88.263  1.00 35.76  ? 9   PHE B CG  1 
ATOM   2052  C  CD1 . PHE B 1 9   ? 86.909  77.394  88.484  1.00 34.90  ? 9   PHE B CD1 1 
ATOM   2053  C  CD2 . PHE B 1 9   ? 87.372  75.221  89.357  1.00 36.11  ? 9   PHE B CD2 1 
ATOM   2054  C  CE1 . PHE B 1 9   ? 86.888  77.915  89.765  1.00 36.27  ? 9   PHE B CE1 1 
ATOM   2055  C  CE2 . PHE B 1 9   ? 87.345  75.731  90.652  1.00 34.93  ? 9   PHE B CE2 1 
ATOM   2056  C  CZ  . PHE B 1 9   ? 87.102  77.079  90.860  1.00 38.23  ? 9   PHE B CZ  1 
ATOM   2057  N  N   . GLN B 1 10  ? 88.299  73.556  84.971  1.00 30.64  ? 10  GLN B N   1 
ATOM   2058  C  CA  . GLN B 1 10  ? 88.102  72.663  83.835  1.00 35.65  ? 10  GLN B CA  1 
ATOM   2059  C  C   . GLN B 1 10  ? 87.401  71.394  84.300  1.00 35.37  ? 10  GLN B C   1 
ATOM   2060  O  O   . GLN B 1 10  ? 87.723  70.858  85.362  1.00 37.65  ? 10  GLN B O   1 
ATOM   2061  C  CB  . GLN B 1 10  ? 89.438  72.341  83.137  1.00 35.75  ? 10  GLN B CB  1 
ATOM   2062  C  CG  . GLN B 1 10  ? 90.242  71.174  83.715  1.00 36.58  ? 10  GLN B CG  1 
ATOM   2063  C  CD  . GLN B 1 10  ? 91.507  70.908  82.913  1.00 39.51  ? 10  GLN B CD  1 
ATOM   2064  O  OE1 . GLN B 1 10  ? 92.511  71.608  83.060  1.00 38.45  ? 10  GLN B OE1 1 
ATOM   2065  N  NE2 . GLN B 1 10  ? 91.450  69.909  82.030  1.00 37.13  ? 10  GLN B NE2 1 
ATOM   2066  N  N   . THR B 1 11  ? 86.423  70.933  83.518  1.00 32.14  ? 11  THR B N   1 
ATOM   2067  C  CA  . THR B 1 11  ? 85.818  69.622  83.764  1.00 37.96  ? 11  THR B CA  1 
ATOM   2068  C  C   . THR B 1 11  ? 86.558  68.566  82.939  1.00 39.97  ? 11  THR B C   1 
ATOM   2069  O  O   . THR B 1 11  ? 86.065  68.042  81.936  1.00 35.61  ? 11  THR B O   1 
ATOM   2070  C  CB  . THR B 1 11  ? 84.331  69.624  83.432  1.00 36.30  ? 11  THR B CB  1 
ATOM   2071  O  OG1 . THR B 1 11  ? 84.168  69.893  82.038  1.00 36.06  ? 11  THR B OG1 1 
ATOM   2072  C  CG2 . THR B 1 11  ? 83.590  70.677  84.227  1.00 37.19  ? 11  THR B CG2 1 
ATOM   2073  N  N   . GLY B 1 12  ? 87.774  68.258  83.386  1.00 38.11  ? 12  GLY B N   1 
ATOM   2074  C  CA  . GLY B 1 12  ? 88.533  67.208  82.722  1.00 38.31  ? 12  GLY B CA  1 
ATOM   2075  C  C   . GLY B 1 12  ? 88.809  67.542  81.270  1.00 37.83  ? 12  GLY B C   1 
ATOM   2076  O  O   . GLY B 1 12  ? 89.033  68.701  80.902  1.00 35.32  ? 12  GLY B O   1 
ATOM   2077  N  N   . THR B 1 13  ? 88.783  66.519  80.421  1.00 33.90  ? 13  THR B N   1 
ATOM   2078  C  CA  . THR B 1 13  ? 89.143  66.688  79.021  1.00 35.93  ? 13  THR B CA  1 
ATOM   2079  C  C   . THR B 1 13  ? 88.091  66.064  78.116  1.00 39.09  ? 13  THR B C   1 
ATOM   2080  O  O   . THR B 1 13  ? 87.143  65.416  78.571  1.00 37.51  ? 13  THR B O   1 
ATOM   2081  C  CB  . THR B 1 13  ? 90.519  66.077  78.701  1.00 37.70  ? 13  THR B CB  1 
ATOM   2082  O  OG1 . THR B 1 13  ? 90.532  64.691  79.057  1.00 40.55  ? 13  THR B OG1 1 
ATOM   2083  C  CG2 . THR B 1 13  ? 91.638  66.819  79.427  1.00 34.49  ? 13  THR B CG2 1 
ATOM   2084  N  N   . LEU B 1 14  ? 88.271  66.285  76.816  1.00 35.44  ? 14  LEU B N   1 
ATOM   2085  C  CA  . LEU B 1 14  ? 87.519  65.598  75.777  1.00 35.18  ? 14  LEU B CA  1 
ATOM   2086  C  C   . LEU B 1 14  ? 88.491  64.828  74.902  1.00 42.45  ? 14  LEU B C   1 
ATOM   2087  O  O   . LEU B 1 14  ? 89.501  65.385  74.456  1.00 41.32  ? 14  LEU B O   1 
ATOM   2088  C  CB  . LEU B 1 14  ? 86.734  66.575  74.903  1.00 39.25  ? 14  LEU B CB  1 
ATOM   2089  C  CG  . LEU B 1 14  ? 85.414  67.142  75.417  1.00 39.10  ? 14  LEU B CG  1 
ATOM   2090  C  CD1 . LEU B 1 14  ? 84.772  67.972  74.322  1.00 42.03  ? 14  LEU B CD1 1 
ATOM   2091  C  CD2 . LEU B 1 14  ? 84.490  66.026  75.858  1.00 39.50  ? 14  LEU B CD2 1 
ATOM   2092  N  N   . LYS B 1 15  ? 88.182  63.563  74.637  1.00 44.28  ? 15  LYS B N   1 
ATOM   2093  C  CA  . LYS B 1 15  ? 88.939  62.779  73.669  1.00 46.39  ? 15  LYS B CA  1 
ATOM   2094  C  C   . LYS B 1 15  ? 88.183  62.763  72.351  1.00 43.93  ? 15  LYS B C   1 
ATOM   2095  O  O   . LYS B 1 15  ? 86.997  62.418  72.314  1.00 43.36  ? 15  LYS B O   1 
ATOM   2096  C  CB  . LYS B 1 15  ? 89.192  61.349  74.159  1.00 46.23  ? 15  LYS B CB  1 
ATOM   2097  C  CG  . LYS B 1 15  ? 90.231  61.238  75.268  1.00 49.99  ? 15  LYS B CG  1 
ATOM   2098  C  CD  . LYS B 1 15  ? 91.167  60.057  75.025  1.00 59.01  ? 15  LYS B CD  1 
ATOM   2099  C  CE  . LYS B 1 15  ? 91.358  59.222  76.282  1.00 58.56  ? 15  LYS B CE  1 
ATOM   2100  N  NZ  . LYS B 1 15  ? 91.447  57.762  75.971  1.00 71.26  ? 15  LYS B NZ  1 
ATOM   2101  N  N   . CYS B 1 16  ? 88.872  63.140  71.282  1.00 39.98  ? 16  CYS B N   1 
ATOM   2102  C  CA  . CYS B 1 16  ? 88.289  63.245  69.953  1.00 48.06  ? 16  CYS B CA  1 
ATOM   2103  C  C   . CYS B 1 16  ? 89.421  63.069  68.948  1.00 50.17  ? 16  CYS B C   1 
ATOM   2104  O  O   . CYS B 1 16  ? 90.488  62.549  69.287  1.00 54.36  ? 16  CYS B O   1 
ATOM   2105  C  CB  . CYS B 1 16  ? 87.542  64.586  69.800  1.00 48.37  ? 16  CYS B CB  1 
ATOM   2106  S  SG  . CYS B 1 16  ? 88.585  66.078  69.954  1.00 45.68  ? 16  CYS B SG  1 
ATOM   2107  N  N   . ARG B 1 17  ? 89.202  63.514  67.715  1.00 53.15  ? 17  ARG B N   1 
ATOM   2108  C  CA  . ARG B 1 17  ? 90.218  63.474  66.674  1.00 56.08  ? 17  ARG B CA  1 
ATOM   2109  C  C   . ARG B 1 17  ? 90.740  64.883  66.433  1.00 54.01  ? 17  ARG B C   1 
ATOM   2110  O  O   . ARG B 1 17  ? 90.121  65.871  66.838  1.00 54.73  ? 17  ARG B O   1 
ATOM   2111  C  CB  . ARG B 1 17  ? 89.657  62.885  65.374  1.00 54.81  ? 17  ARG B CB  1 
ATOM   2112  C  CG  . ARG B 1 17  ? 89.308  61.401  65.465  1.00 61.97  ? 17  ARG B CG  1 
ATOM   2113  C  CD  . ARG B 1 17  ? 89.972  60.622  64.343  1.00 72.12  ? 17  ARG B CD  1 
ATOM   2114  N  NE  . ARG B 1 17  ? 91.287  60.125  64.737  1.00 76.74  ? 17  ARG B NE  1 
ATOM   2115  C  CZ  . ARG B 1 17  ? 91.518  58.932  65.268  1.00 78.42  ? 17  ARG B CZ  1 
ATOM   2116  N  NH1 . ARG B 1 17  ? 90.555  58.031  65.392  1.00 77.16  ? 17  ARG B NH1 1 
ATOM   2117  N  NH2 . ARG B 1 17  ? 92.750  58.625  65.663  1.00 76.06  ? 17  ARG B NH2 1 
ATOM   2118  N  N   . VAL B 1 18  ? 91.896  64.969  65.771  1.00 55.89  ? 18  VAL B N   1 
ATOM   2119  C  CA  . VAL B 1 18  ? 92.439  66.275  65.406  1.00 54.26  ? 18  VAL B CA  1 
ATOM   2120  C  C   . VAL B 1 18  ? 91.419  67.049  64.586  1.00 51.20  ? 18  VAL B C   1 
ATOM   2121  O  O   . VAL B 1 18  ? 91.147  68.225  64.851  1.00 47.41  ? 18  VAL B O   1 
ATOM   2122  C  CB  . VAL B 1 18  ? 93.769  66.123  64.643  1.00 51.75  ? 18  VAL B CB  1 
ATOM   2123  C  CG1 . VAL B 1 18  ? 93.974  67.292  63.700  1.00 52.75  ? 18  VAL B CG1 1 
ATOM   2124  C  CG2 . VAL B 1 18  ? 94.930  66.021  65.611  1.00 57.69  ? 18  VAL B CG2 1 
ATOM   2125  N  N   . CYS B 1 19  ? 90.804  66.377  63.607  1.00 51.29  ? 19  CYS B N   1 
ATOM   2126  C  CA  . CYS B 1 19  ? 89.944  67.055  62.642  1.00 51.92  ? 19  CYS B CA  1 
ATOM   2127  C  C   . CYS B 1 19  ? 88.734  67.718  63.299  1.00 50.39  ? 19  CYS B C   1 
ATOM   2128  O  O   . CYS B 1 19  ? 88.269  68.756  62.810  1.00 50.90  ? 19  CYS B O   1 
ATOM   2129  C  CB  . CYS B 1 19  ? 89.496  66.069  61.559  1.00 50.66  ? 19  CYS B CB  1 
ATOM   2130  S  SG  . CYS B 1 19  ? 88.531  64.672  62.179  1.00 51.80  ? 19  CYS B SG  1 
ATOM   2131  N  N   . ASN B 1 20  ? 88.213  67.151  64.399  1.00 47.40  ? 20  ASN B N   1 
ATOM   2132  C  CA  . ASN B 1 20  ? 87.115  67.802  65.117  1.00 49.84  ? 20  ASN B CA  1 
ATOM   2133  C  C   . ASN B 1 20  ? 87.497  69.182  65.652  1.00 48.03  ? 20  ASN B C   1 
ATOM   2134  O  O   . ASN B 1 20  ? 86.612  69.999  65.923  1.00 47.58  ? 20  ASN B O   1 
ATOM   2135  C  CB  . ASN B 1 20  ? 86.630  66.940  66.288  1.00 50.17  ? 20  ASN B CB  1 
ATOM   2136  C  CG  . ASN B 1 20  ? 86.256  65.518  65.875  1.00 50.93  ? 20  ASN B CG  1 
ATOM   2137  O  OD1 . ASN B 1 20  ? 86.796  64.551  66.402  1.00 49.05  ? 20  ASN B OD1 1 
ATOM   2138  N  ND2 . ASN B 1 20  ? 85.304  65.392  64.956  1.00 49.08  ? 20  ASN B ND2 1 
ATOM   2139  N  N   . ILE B 1 21  ? 88.787  69.450  65.821  1.00 46.42  ? 21  ILE B N   1 
ATOM   2140  C  CA  . ILE B 1 21  ? 89.279  70.733  66.306  1.00 45.27  ? 21  ILE B CA  1 
ATOM   2141  C  C   . ILE B 1 21  ? 89.785  71.597  65.156  1.00 44.12  ? 21  ILE B C   1 
ATOM   2142  O  O   . ILE B 1 21  ? 89.368  72.746  65.004  1.00 41.60  ? 21  ILE B O   1 
ATOM   2143  C  CB  . ILE B 1 21  ? 90.379  70.513  67.374  1.00 47.55  ? 21  ILE B CB  1 
ATOM   2144  C  CG1 . ILE B 1 21  ? 89.834  69.745  68.583  1.00 46.63  ? 21  ILE B CG1 1 
ATOM   2145  C  CG2 . ILE B 1 21  ? 90.962  71.835  67.844  1.00 47.36  ? 21  ILE B CG2 1 
ATOM   2146  C  CD1 . ILE B 1 21  ? 88.417  70.091  68.959  1.00 46.19  ? 21  ILE B CD1 1 
ATOM   2147  N  N   . LYS B 1 22  ? 90.704  71.059  64.342  1.00 46.05  ? 22  LYS B N   1 
ATOM   2148  C  CA  . LYS B 1 22  ? 91.241  71.724  63.155  1.00 46.37  ? 22  LYS B CA  1 
ATOM   2149  C  C   . LYS B 1 22  ? 90.707  70.980  61.935  1.00 48.55  ? 22  LYS B C   1 
ATOM   2150  O  O   . LYS B 1 22  ? 91.110  69.839  61.672  1.00 49.54  ? 22  LYS B O   1 
ATOM   2151  C  CB  . LYS B 1 22  ? 92.767  71.720  63.179  1.00 45.70  ? 22  LYS B CB  1 
ATOM   2152  C  CG  . LYS B 1 22  ? 93.369  71.793  64.579  1.00 47.37  ? 22  LYS B CG  1 
ATOM   2153  C  CD  . LYS B 1 22  ? 94.807  72.255  64.567  1.00 46.98  ? 22  LYS B CD  1 
ATOM   2154  C  CE  . LYS B 1 22  ? 95.258  72.642  65.969  1.00 51.84  ? 22  LYS B CE  1 
ATOM   2155  N  NZ  . LYS B 1 22  ? 96.658  73.165  65.987  1.00 48.23  ? 22  LYS B NZ  1 
ATOM   2156  N  N   . MET B 1 23  ? 89.806  71.626  61.197  1.00 45.05  ? 23  MET B N   1 
ATOM   2157  C  CA  . MET B 1 23  ? 89.074  70.959  60.124  1.00 45.71  ? 23  MET B CA  1 
ATOM   2158  C  C   . MET B 1 23  ? 90.028  70.428  59.055  1.00 46.44  ? 23  MET B C   1 
ATOM   2159  O  O   . MET B 1 23  ? 91.001  71.094  58.681  1.00 45.67  ? 23  MET B O   1 
ATOM   2160  C  CB  . MET B 1 23  ? 88.061  71.935  59.501  1.00 45.43  ? 23  MET B CB  1 
ATOM   2161  C  CG  . MET B 1 23  ? 87.135  71.339  58.441  1.00 45.63  ? 23  MET B CG  1 
ATOM   2162  S  SD  . MET B 1 23  ? 86.271  72.598  57.468  1.00 44.62  ? 23  MET B SD  1 
ATOM   2163  C  CE  . MET B 1 23  ? 87.606  73.276  56.481  1.00 45.05  ? 23  MET B CE  1 
ATOM   2164  N  N   . ASN B 1 24  ? 89.758  69.200  58.589  1.00 46.13  ? 24  ASN B N   1 
ATOM   2165  C  CA  . ASN B 1 24  ? 90.504  68.569  57.490  1.00 46.34  ? 24  ASN B CA  1 
ATOM   2166  C  C   . ASN B 1 24  ? 91.995  68.457  57.793  1.00 43.03  ? 24  ASN B C   1 
ATOM   2167  O  O   . ASN B 1 24  ? 92.821  68.464  56.881  1.00 46.26  ? 24  ASN B O   1 
ATOM   2168  C  CB  . ASN B 1 24  ? 90.287  69.313  56.165  1.00 43.24  ? 24  ASN B CB  1 
ATOM   2169  C  CG  . ASN B 1 24  ? 88.806  69.423  55.790  1.00 47.76  ? 24  ASN B CG  1 
ATOM   2170  O  OD1 . ASN B 1 24  ? 87.978  68.634  56.258  1.00 41.79  ? 24  ASN B OD1 1 
ATOM   2171  N  ND2 . ASN B 1 24  ? 88.467  70.416  54.961  1.00 44.04  ? 24  ASN B ND2 1 
ATOM   2172  N  N   . ALA B 1 25  ? 92.358  68.358  59.072  1.00 48.97  ? 25  ALA B N   1 
ATOM   2173  C  CA  . ALA B 1 25  ? 93.759  68.315  59.482  1.00 50.68  ? 25  ALA B CA  1 
ATOM   2174  C  C   . ALA B 1 25  ? 94.214  66.938  59.942  1.00 53.23  ? 25  ALA B C   1 
ATOM   2175  O  O   . ALA B 1 25  ? 95.381  66.776  60.284  1.00 54.93  ? 25  ALA B O   1 
ATOM   2176  C  CB  . ALA B 1 25  ? 94.035  69.344  60.586  1.00 46.68  ? 25  ALA B CB  1 
ATOM   2177  N  N   . GLY B 1 26  ? 93.339  65.952  59.966  1.00 57.07  ? 26  GLY B N   1 
ATOM   2178  C  CA  . GLY B 1 26  ? 93.750  64.566  60.074  1.00 61.44  ? 26  GLY B CA  1 
ATOM   2179  C  C   . GLY B 1 26  ? 92.908  63.764  61.049  1.00 64.44  ? 26  GLY B C   1 
ATOM   2180  O  O   . GLY B 1 26  ? 92.130  64.291  61.851  1.00 64.07  ? 26  GLY B O   1 
ATOM   2181  N  N   . LEU B 1 27  ? 93.077  62.449  60.982  1.00 68.06  ? 27  LEU B N   1 
ATOM   2182  C  CA  . LEU B 1 27  ? 92.408  61.529  61.891  1.00 68.71  ? 27  LEU B CA  1 
ATOM   2183  C  C   . LEU B 1 27  ? 93.392  60.985  62.917  1.00 73.08  ? 27  LEU B C   1 
ATOM   2184  O  O   . LEU B 1 27  ? 93.579  59.768  63.019  1.00 91.11  ? 27  LEU B O   1 
ATOM   2185  C  CB  . LEU B 1 27  ? 91.773  60.361  61.131  1.00 66.47  ? 27  LEU B CB  1 
ATOM   2186  C  CG  . LEU B 1 27  ? 90.860  60.678  59.950  1.00 67.17  ? 27  LEU B CG  1 
ATOM   2187  C  CD1 . LEU B 1 27  ? 90.229  59.392  59.424  1.00 65.72  ? 27  LEU B CD1 1 
ATOM   2188  C  CD2 . LEU B 1 27  ? 89.800  61.696  60.346  1.00 63.64  ? 27  LEU B CD2 1 
ATOM   2189  N  N   . ASP B 1 28  ? 94.035  61.866  63.668  1.00 69.53  ? 28  ASP B N   1 
ATOM   2190  C  CA  . ASP B 1 28  ? 94.854  61.461  64.797  1.00 68.20  ? 28  ASP B CA  1 
ATOM   2191  C  C   . ASP B 1 28  ? 94.056  61.624  66.081  1.00 67.85  ? 28  ASP B C   1 
ATOM   2192  O  O   . ASP B 1 28  ? 93.174  62.479  66.176  1.00 67.03  ? 28  ASP B O   1 
ATOM   2193  C  CB  . ASP B 1 28  ? 96.135  62.292  64.879  1.00 72.40  ? 28  ASP B CB  1 
ATOM   2194  C  CG  . ASP B 1 28  ? 97.104  61.985  63.757  1.00 78.09  ? 28  ASP B CG  1 
ATOM   2195  O  OD1 . ASP B 1 28  ? 97.325  60.786  63.475  1.00 75.15  ? 28  ASP B OD1 1 
ATOM   2196  O  OD2 . ASP B 1 28  ? 97.650  62.944  63.165  1.00 76.04  ? 28  ASP B OD2 1 
ATOM   2197  N  N   . ASP B 1 29  ? 94.368  60.791  67.069  1.00 65.66  ? 29  ASP B N   1 
ATOM   2198  C  CA  . ASP B 1 29  ? 93.788  60.980  68.387  1.00 61.91  ? 29  ASP B CA  1 
ATOM   2199  C  C   . ASP B 1 29  ? 94.197  62.339  68.941  1.00 58.16  ? 29  ASP B C   1 
ATOM   2200  O  O   . ASP B 1 29  ? 95.280  62.852  68.650  1.00 60.83  ? 29  ASP B O   1 
ATOM   2201  C  CB  . ASP B 1 29  ? 94.229  59.865  69.327  1.00 62.67  ? 29  ASP B CB  1 
ATOM   2202  C  CG  . ASP B 1 29  ? 93.759  58.505  68.865  1.00 70.57  ? 29  ASP B CG  1 
ATOM   2203  O  OD1 . ASP B 1 29  ? 92.536  58.244  68.930  1.00 68.56  ? 29  ASP B OD1 1 
ATOM   2204  O  OD2 . ASP B 1 29  ? 94.611  57.701  68.420  1.00 76.51  ? 29  ASP B OD2 1 
ATOM   2205  N  N   . TYR B 1 30  ? 93.312  62.924  69.742  1.00 50.54  ? 30  TYR B N   1 
ATOM   2206  C  CA  . TYR B 1 30  ? 93.481  64.283  70.229  1.00 49.64  ? 30  TYR B CA  1 
ATOM   2207  C  C   . TYR B 1 30  ? 92.735  64.412  71.545  1.00 48.65  ? 30  TYR B C   1 
ATOM   2208  O  O   . TYR B 1 30  ? 91.684  63.796  71.733  1.00 47.93  ? 30  TYR B O   1 
ATOM   2209  C  CB  . TYR B 1 30  ? 92.947  65.292  69.203  1.00 52.69  ? 30  TYR B CB  1 
ATOM   2210  C  CG  . TYR B 1 30  ? 93.501  66.700  69.280  1.00 54.26  ? 30  TYR B CG  1 
ATOM   2211  C  CD1 . TYR B 1 30  ? 94.834  66.964  68.988  1.00 56.56  ? 30  TYR B CD1 1 
ATOM   2212  C  CD2 . TYR B 1 30  ? 92.669  67.780  69.569  1.00 54.41  ? 30  TYR B CD2 1 
ATOM   2213  C  CE1 . TYR B 1 30  ? 95.335  68.258  69.026  1.00 55.81  ? 30  TYR B CE1 1 
ATOM   2214  C  CE2 . TYR B 1 30  ? 93.161  69.076  69.604  1.00 48.97  ? 30  TYR B CE2 1 
ATOM   2215  C  CZ  . TYR B 1 30  ? 94.491  69.307  69.333  1.00 55.26  ? 30  TYR B CZ  1 
ATOM   2216  O  OH  . TYR B 1 30  ? 94.986  70.590  69.371  1.00 59.11  ? 30  TYR B OH  1 
ATOM   2217  N  N   . GLU B 1 31  ? 93.289  65.200  72.456  1.00 48.66  ? 31  GLU B N   1 
ATOM   2218  C  CA  . GLU B 1 31  ? 92.656  65.473  73.733  1.00 44.13  ? 31  GLU B CA  1 
ATOM   2219  C  C   . GLU B 1 31  ? 92.689  66.976  73.983  1.00 45.69  ? 31  GLU B C   1 
ATOM   2220  O  O   . GLU B 1 31  ? 93.684  67.641  73.680  1.00 45.00  ? 31  GLU B O   1 
ATOM   2221  C  CB  . GLU B 1 31  ? 93.353  64.716  74.860  1.00 42.92  ? 31  GLU B CB  1 
ATOM   2222  C  CG  . GLU B 1 31  ? 92.515  64.598  76.116  1.00 48.91  ? 31  GLU B CG  1 
ATOM   2223  C  CD  . GLU B 1 31  ? 92.923  63.429  77.008  1.00 52.26  ? 31  GLU B CD  1 
ATOM   2224  O  OE1 . GLU B 1 31  ? 93.744  62.587  76.571  1.00 56.11  ? 31  GLU B OE1 1 
ATOM   2225  O  OE2 . GLU B 1 31  ? 92.417  63.357  78.150  1.00 46.10  ? 31  GLU B OE2 1 
ATOM   2226  N  N   . ILE B 1 32  ? 91.593  67.516  74.510  1.00 42.98  ? 32  ILE B N   1 
ATOM   2227  C  CA  . ILE B 1 32  ? 91.516  68.952  74.772  1.00 35.10  ? 32  ILE B CA  1 
ATOM   2228  C  C   . ILE B 1 32  ? 91.006  69.181  76.186  1.00 33.69  ? 32  ILE B C   1 
ATOM   2229  O  O   . ILE B 1 32  ? 90.180  68.400  76.676  1.00 36.53  ? 32  ILE B O   1 
ATOM   2230  C  CB  . ILE B 1 32  ? 90.603  69.659  73.759  1.00 37.11  ? 32  ILE B CB  1 
ATOM   2231  C  CG1 . ILE B 1 32  ? 89.235  68.967  73.713  1.00 37.82  ? 32  ILE B CG1 1 
ATOM   2232  C  CG2 . ILE B 1 32  ? 91.260  69.730  72.387  1.00 36.90  ? 32  ILE B CG2 1 
ATOM   2233  C  CD1 . ILE B 1 32  ? 88.323  69.527  72.652  1.00 39.12  ? 32  ILE B CD1 1 
ATOM   2234  N  N   . PRO B 1 33  ? 91.451  70.233  76.865  1.00 33.43  ? 33  PRO B N   1 
ATOM   2235  C  CA  . PRO B 1 33  ? 90.821  70.617  78.133  1.00 31.67  ? 33  PRO B CA  1 
ATOM   2236  C  C   . PRO B 1 33  ? 89.434  71.201  77.890  1.00 35.67  ? 33  PRO B C   1 
ATOM   2237  O  O   . PRO B 1 33  ? 89.128  71.701  76.805  1.00 35.06  ? 33  PRO B O   1 
ATOM   2238  C  CB  . PRO B 1 33  ? 91.768  71.683  78.688  1.00 34.28  ? 33  PRO B CB  1 
ATOM   2239  C  CG  . PRO B 1 33  ? 92.419  72.276  77.476  1.00 32.76  ? 33  PRO B CG  1 
ATOM   2240  C  CD  . PRO B 1 33  ? 92.484  71.193  76.434  1.00 34.32  ? 33  PRO B CD  1 
ATOM   2241  N  N   . VAL B 1 34  ? 88.597  71.148  78.926  1.00 33.20  ? 34  VAL B N   1 
ATOM   2242  C  CA  . VAL B 1 34  ? 87.250  71.718  78.870  1.00 32.03  ? 34  VAL B CA  1 
ATOM   2243  C  C   . VAL B 1 34  ? 87.154  72.847  79.890  1.00 35.62  ? 34  VAL B C   1 
ATOM   2244  O  O   . VAL B 1 34  ? 86.713  72.622  81.025  1.00 33.23  ? 34  VAL B O   1 
ATOM   2245  C  CB  . VAL B 1 34  ? 86.167  70.655  79.119  1.00 36.44  ? 34  VAL B CB  1 
ATOM   2246  C  CG1 . VAL B 1 34  ? 84.764  71.286  79.073  1.00 36.50  ? 34  VAL B CG1 1 
ATOM   2247  C  CG2 . VAL B 1 34  ? 86.278  69.535  78.097  1.00 34.43  ? 34  VAL B CG2 1 
ATOM   2248  N  N   . PRO B 1 35  ? 87.563  74.063  79.537  1.00 34.37  ? 35  PRO B N   1 
ATOM   2249  C  CA  . PRO B 1 35  ? 87.556  75.161  80.507  1.00 35.92  ? 35  PRO B CA  1 
ATOM   2250  C  C   . PRO B 1 35  ? 86.153  75.547  80.955  1.00 31.13  ? 35  PRO B C   1 
ATOM   2251  O  O   . PRO B 1 35  ? 85.155  75.323  80.270  1.00 32.84  ? 35  PRO B O   1 
ATOM   2252  C  CB  . PRO B 1 35  ? 88.213  76.313  79.736  1.00 32.18  ? 35  PRO B CB  1 
ATOM   2253  C  CG  . PRO B 1 35  ? 89.013  75.634  78.646  1.00 34.91  ? 35  PRO B CG  1 
ATOM   2254  C  CD  . PRO B 1 35  ? 88.176  74.459  78.260  1.00 36.21  ? 35  PRO B CD  1 
ATOM   2255  N  N   . TRP B 1 36  ? 86.095  76.151  82.133  1.00 26.84  ? 36  TRP B N   1 
ATOM   2256  C  CA  . TRP B 1 36  ? 84.945  76.954  82.528  1.00 27.15  ? 36  TRP B CA  1 
ATOM   2257  C  C   . TRP B 1 36  ? 85.435  77.931  83.584  1.00 30.62  ? 36  TRP B C   1 
ATOM   2258  O  O   . TRP B 1 36  ? 86.529  77.773  84.135  1.00 28.28  ? 36  TRP B O   1 
ATOM   2259  C  CB  . TRP B 1 36  ? 83.774  76.099  83.024  1.00 29.43  ? 36  TRP B CB  1 
ATOM   2260  C  CG  . TRP B 1 36  ? 84.007  75.356  84.289  1.00 33.37  ? 36  TRP B CG  1 
ATOM   2261  C  CD1 . TRP B 1 36  ? 84.528  74.097  84.415  1.00 32.61  ? 36  TRP B CD1 1 
ATOM   2262  C  CD2 . TRP B 1 36  ? 83.705  75.802  85.618  1.00 30.76  ? 36  TRP B CD2 1 
ATOM   2263  N  NE1 . TRP B 1 36  ? 84.572  73.737  85.733  1.00 33.40  ? 36  TRP B NE1 1 
ATOM   2264  C  CE2 . TRP B 1 36  ? 84.071  74.762  86.497  1.00 33.01  ? 36  TRP B CE2 1 
ATOM   2265  C  CE3 . TRP B 1 36  ? 83.169  76.978  86.150  1.00 32.28  ? 36  TRP B CE3 1 
ATOM   2266  C  CZ2 . TRP B 1 36  ? 83.923  74.865  87.882  1.00 29.93  ? 36  TRP B CZ2 1 
ATOM   2267  C  CZ3 . TRP B 1 36  ? 83.020  77.080  87.536  1.00 32.96  ? 36  TRP B CZ3 1 
ATOM   2268  C  CH2 . TRP B 1 36  ? 83.399  76.029  88.380  1.00 31.38  ? 36  TRP B CH2 1 
ATOM   2269  N  N   . TYR B 1 37  ? 84.642  78.967  83.832  1.00 24.85  ? 37  TYR B N   1 
ATOM   2270  C  CA  . TYR B 1 37  ? 85.164  80.112  84.547  1.00 23.02  ? 37  TYR B CA  1 
ATOM   2271  C  C   . TYR B 1 37  ? 84.232  80.521  85.672  1.00 32.20  ? 37  TYR B C   1 
ATOM   2272  O  O   . TYR B 1 37  ? 83.000  80.373  85.596  1.00 24.95  ? 37  TYR B O   1 
ATOM   2273  C  CB  . TYR B 1 37  ? 85.409  81.286  83.597  1.00 25.85  ? 37  TYR B CB  1 
ATOM   2274  C  CG  . TYR B 1 37  ? 86.075  80.857  82.310  1.00 24.15  ? 37  TYR B CG  1 
ATOM   2275  C  CD1 . TYR B 1 37  ? 87.459  80.721  82.225  1.00 29.64  ? 37  TYR B CD1 1 
ATOM   2276  C  CD2 . TYR B 1 37  ? 85.317  80.549  81.186  1.00 24.74  ? 37  TYR B CD2 1 
ATOM   2277  C  CE1 . TYR B 1 37  ? 88.073  80.308  81.040  1.00 27.71  ? 37  TYR B CE1 1 
ATOM   2278  C  CE2 . TYR B 1 37  ? 85.913  80.141  80.006  1.00 28.81  ? 37  TYR B CE2 1 
ATOM   2279  C  CZ  . TYR B 1 37  ? 87.286  80.019  79.933  1.00 26.74  ? 37  TYR B CZ  1 
ATOM   2280  O  OH  . TYR B 1 37  ? 87.858  79.614  78.743  1.00 28.07  ? 37  TYR B OH  1 
ATOM   2281  N  N   . LEU B 1 38  ? 84.852  81.011  86.739  1.00 28.23  ? 38  LEU B N   1 
ATOM   2282  C  CA  . LEU B 1 38  ? 84.147  81.658  87.826  1.00 28.61  ? 38  LEU B CA  1 
ATOM   2283  C  C   . LEU B 1 38  ? 84.702  83.062  87.978  1.00 29.67  ? 38  LEU B C   1 
ATOM   2284  O  O   . LEU B 1 38  ? 85.926  83.260  87.950  1.00 29.25  ? 38  LEU B O   1 
ATOM   2285  C  CB  . LEU B 1 38  ? 84.303  80.872  89.124  1.00 33.41  ? 38  LEU B CB  1 
ATOM   2286  C  CG  . LEU B 1 38  ? 83.999  81.605  90.425  1.00 26.59  ? 38  LEU B CG  1 
ATOM   2287  C  CD1 . LEU B 1 38  ? 82.505  81.675  90.666  1.00 26.55  ? 38  LEU B CD1 1 
ATOM   2288  C  CD2 . LEU B 1 38  ? 84.695  80.861  91.569  1.00 35.62  ? 38  LEU B CD2 1 
ATOM   2289  N  N   . ILE B 1 39  ? 83.805  84.030  88.128  1.00 28.85  ? 39  ILE B N   1 
ATOM   2290  C  CA  . ILE B 1 39  ? 84.166  85.399  88.475  1.00 26.82  ? 39  ILE B CA  1 
ATOM   2291  C  C   . ILE B 1 39  ? 83.509  85.700  89.809  1.00 31.59  ? 39  ILE B C   1 
ATOM   2292  O  O   . ILE B 1 39  ? 82.276  85.643  89.925  1.00 27.68  ? 39  ILE B O   1 
ATOM   2293  C  CB  . ILE B 1 39  ? 83.717  86.421  87.415  1.00 31.09  ? 39  ILE B CB  1 
ATOM   2294  C  CG1 . ILE B 1 39  ? 84.470  86.229  86.090  1.00 26.63  ? 39  ILE B CG1 1 
ATOM   2295  C  CG2 . ILE B 1 39  ? 83.923  87.843  87.948  1.00 30.80  ? 39  ILE B CG2 1 
ATOM   2296  C  CD1 . ILE B 1 39  ? 83.869  85.209  85.176  1.00 28.68  ? 39  ILE B CD1 1 
ATOM   2297  N  N   . THR B 1 40  ? 84.325  85.997  90.818  1.00 31.64  ? 40  THR B N   1 
ATOM   2298  C  CA  . THR B 1 40  ? 83.813  86.393  92.123  1.00 29.68  ? 40  THR B CA  1 
ATOM   2299  C  C   . THR B 1 40  ? 83.753  87.907  92.136  1.00 35.01  ? 40  THR B C   1 
ATOM   2300  O  O   . THR B 1 40  ? 84.767  88.568  91.908  1.00 35.70  ? 40  THR B O   1 
ATOM   2301  C  CB  . THR B 1 40  ? 84.712  85.895  93.247  1.00 30.21  ? 40  THR B CB  1 
ATOM   2302  O  OG1 . THR B 1 40  ? 86.031  86.410  93.037  1.00 33.10  ? 40  THR B OG1 1 
ATOM   2303  C  CG2 . THR B 1 40  ? 84.768  84.371  93.249  1.00 33.68  ? 40  THR B CG2 1 
ATOM   2304  N  N   . HIS B 1 41  ? 82.579  88.454  92.407  1.00 34.44  ? 41  HIS B N   1 
ATOM   2305  C  CA  . HIS B 1 41  ? 82.377  89.869  92.241  1.00 36.44  ? 41  HIS B CA  1 
ATOM   2306  C  C   . HIS B 1 41  ? 81.651  90.347  93.486  1.00 32.83  ? 41  HIS B C   1 
ATOM   2307  O  O   . HIS B 1 41  ? 80.780  89.633  93.999  1.00 32.72  ? 41  HIS B O   1 
ATOM   2308  C  CB  . HIS B 1 41  ? 81.561  90.152  90.971  1.00 32.02  ? 41  HIS B CB  1 
ATOM   2309  C  CG  . HIS B 1 41  ? 81.402  91.604  90.639  1.00 34.36  ? 41  HIS B CG  1 
ATOM   2310  N  ND1 . HIS B 1 41  ? 80.554  92.442  91.333  1.00 35.04  ? 41  HIS B ND1 1 
ATOM   2311  C  CD2 . HIS B 1 41  ? 81.947  92.356  89.653  1.00 33.43  ? 41  HIS B CD2 1 
ATOM   2312  C  CE1 . HIS B 1 41  ? 80.596  93.651  90.799  1.00 35.52  ? 41  HIS B CE1 1 
ATOM   2313  N  NE2 . HIS B 1 41  ? 81.435  93.627  89.778  1.00 31.21  ? 41  HIS B NE2 1 
ATOM   2314  N  N   . PRO B 1 42  ? 82.012  91.518  94.009  1.00 32.53  ? 42  PRO B N   1 
ATOM   2315  C  CA  . PRO B 1 42  ? 81.296  92.076  95.168  1.00 33.12  ? 42  PRO B CA  1 
ATOM   2316  C  C   . PRO B 1 42  ? 79.787  91.939  95.035  1.00 37.60  ? 42  PRO B C   1 
ATOM   2317  O  O   . PRO B 1 42  ? 79.105  91.594  96.004  1.00 35.63  ? 42  PRO B O   1 
ATOM   2318  C  CB  . PRO B 1 42  ? 81.713  93.552  95.168  1.00 34.33  ? 42  PRO B CB  1 
ATOM   2319  C  CG  . PRO B 1 42  ? 82.965  93.626  94.358  1.00 36.06  ? 42  PRO B CG  1 
ATOM   2320  C  CD  . PRO B 1 42  ? 83.150  92.347  93.586  1.00 32.78  ? 42  PRO B CD  1 
ATOM   2321  N  N   . LYS B 1 43  ? 79.260  92.174  93.826  1.00 34.73  ? 43  LYS B N   1 
ATOM   2322  C  CA  . LYS B 1 43  ? 77.823  92.140  93.598  1.00 33.41  ? 43  LYS B CA  1 
ATOM   2323  C  C   . LYS B 1 43  ? 77.286  90.741  93.305  1.00 33.83  ? 43  LYS B C   1 
ATOM   2324  O  O   . LYS B 1 43  ? 76.080  90.597  93.086  1.00 34.94  ? 43  LYS B O   1 
ATOM   2325  C  CB  . LYS B 1 43  ? 77.449  93.088  92.456  1.00 36.17  ? 43  LYS B CB  1 
ATOM   2326  C  CG  . LYS B 1 43  ? 77.672  94.581  92.729  1.00 40.07  ? 43  LYS B CG  1 
ATOM   2327  C  CD  . LYS B 1 43  ? 76.547  95.397  92.096  1.00 53.49  ? 43  LYS B CD  1 
ATOM   2328  C  CE  . LYS B 1 43  ? 77.007  96.782  91.635  1.00 62.88  ? 43  LYS B CE  1 
ATOM   2329  N  NZ  . LYS B 1 43  ? 75.952  97.492  90.825  1.00 66.27  ? 43  LYS B NZ  1 
ATOM   2330  N  N   . GLY B 1 44  ? 78.111  89.710  93.308  1.00 31.13  ? 44  GLY B N   1 
ATOM   2331  C  CA  . GLY B 1 44  ? 77.611  88.355  93.161  1.00 31.01  ? 44  GLY B CA  1 
ATOM   2332  C  C   . GLY B 1 44  ? 78.518  87.521  92.282  1.00 33.13  ? 44  GLY B C   1 
ATOM   2333  O  O   . GLY B 1 44  ? 79.250  88.025  91.434  1.00 32.19  ? 44  GLY B O   1 
ATOM   2334  N  N   . ASN B 1 45  ? 78.460  86.209  92.481  1.00 27.69  ? 45  ASN B N   1 
ATOM   2335  C  CA  . ASN B 1 45  ? 79.359  85.318  91.768  1.00 30.47  ? 45  ASN B CA  1 
ATOM   2336  C  C   . ASN B 1 45  ? 78.795  84.982  90.389  1.00 32.86  ? 45  ASN B C   1 
ATOM   2337  O  O   . ASN B 1 45  ? 77.581  84.906  90.196  1.00 29.85  ? 45  ASN B O   1 
ATOM   2338  C  CB  . ASN B 1 45  ? 79.595  84.035  92.573  1.00 28.81  ? 45  ASN B CB  1 
ATOM   2339  C  CG  . ASN B 1 45  ? 80.307  84.300  93.890  1.00 34.29  ? 45  ASN B CG  1 
ATOM   2340  O  OD1 . ASN B 1 45  ? 81.335  84.963  93.919  1.00 32.27  ? 45  ASN B OD1 1 
ATOM   2341  N  ND2 . ASN B 1 45  ? 79.754  83.793  94.985  1.00 34.12  ? 45  ASN B ND2 1 
ATOM   2342  N  N   . VAL B 1 46  ? 79.696  84.764  89.432  1.00 27.74  ? 46  VAL B N   1 
ATOM   2343  C  CA  . VAL B 1 46  ? 79.340  84.445  88.059  1.00 27.34  ? 46  VAL B CA  1 
ATOM   2344  C  C   . VAL B 1 46  ? 80.001  83.136  87.666  1.00 26.70  ? 46  VAL B C   1 
ATOM   2345  O  O   . VAL B 1 46  ? 81.222  82.993  87.794  1.00 26.79  ? 46  VAL B O   1 
ATOM   2346  C  CB  . VAL B 1 46  ? 79.769  85.557  87.090  1.00 31.13  ? 46  VAL B CB  1 
ATOM   2347  C  CG1 . VAL B 1 46  ? 79.489  85.123  85.656  1.00 26.42  ? 46  VAL B CG1 1 
ATOM   2348  C  CG2 . VAL B 1 46  ? 79.057  86.841  87.420  1.00 29.48  ? 46  VAL B CG2 1 
ATOM   2349  N  N   . VAL B 1 47  ? 79.191  82.189  87.184  1.00 25.90  ? 47  VAL B N   1 
ATOM   2350  C  CA  . VAL B 1 47  ? 79.667  80.995  86.486  1.00 25.48  ? 47  VAL B CA  1 
ATOM   2351  C  C   . VAL B 1 47  ? 79.462  81.183  84.984  1.00 28.75  ? 47  VAL B C   1 
ATOM   2352  O  O   . VAL B 1 47  ? 78.369  81.561  84.541  1.00 28.61  ? 47  VAL B O   1 
ATOM   2353  C  CB  . VAL B 1 47  ? 78.936  79.733  86.971  1.00 27.78  ? 47  VAL B CB  1 
ATOM   2354  C  CG1 . VAL B 1 47  ? 79.398  78.511  86.177  1.00 23.99  ? 47  VAL B CG1 1 
ATOM   2355  C  CG2 . VAL B 1 47  ? 79.155  79.531  88.473  1.00 33.29  ? 47  VAL B CG2 1 
ATOM   2356  N  N   . ILE B 1 48  ? 80.496  80.895  84.201  1.00 27.63  ? 48  ILE B N   1 
ATOM   2357  C  CA  . ILE B 1 48  ? 80.415  80.889  82.744  1.00 26.08  ? 48  ILE B CA  1 
ATOM   2358  C  C   . ILE B 1 48  ? 80.460  79.440  82.277  1.00 30.76  ? 48  ILE B C   1 
ATOM   2359  O  O   . ILE B 1 48  ? 81.466  78.746  82.482  1.00 29.72  ? 48  ILE B O   1 
ATOM   2360  C  CB  . ILE B 1 48  ? 81.553  81.695  82.103  1.00 26.54  ? 48  ILE B CB  1 
ATOM   2361  C  CG1 . ILE B 1 48  ? 81.468  83.174  82.489  1.00 22.19  ? 48  ILE B CG1 1 
ATOM   2362  C  CG2 . ILE B 1 48  ? 81.569  81.474  80.567  1.00 24.04  ? 48  ILE B CG2 1 
ATOM   2363  C  CD1 . ILE B 1 48  ? 82.488  84.036  81.776  1.00 21.58  ? 48  ILE B CD1 1 
ATOM   2364  N  N   . ASP B 1 49  ? 79.368  78.986  81.654  1.00 28.09  ? 49  ASP B N   1 
ATOM   2365  C  CA  . ASP B 1 49  ? 79.260  77.677  81.010  1.00 25.30  ? 49  ASP B CA  1 
ATOM   2366  C  C   . ASP B 1 49  ? 79.187  76.536  82.027  1.00 32.09  ? 49  ASP B C   1 
ATOM   2367  O  O   . ASP B 1 49  ? 78.164  75.849  82.115  1.00 30.90  ? 49  ASP B O   1 
ATOM   2368  C  CB  . ASP B 1 49  ? 80.415  77.460  80.024  1.00 26.87  ? 49  ASP B CB  1 
ATOM   2369  C  CG  . ASP B 1 49  ? 80.223  78.234  78.716  1.00 30.44  ? 49  ASP B CG  1 
ATOM   2370  O  OD1 . ASP B 1 49  ? 79.091  78.729  78.490  1.00 23.75  ? 49  ASP B OD1 1 
ATOM   2371  O  OD2 . ASP B 1 49  ? 81.202  78.362  77.930  1.00 28.73  ? 49  ASP B OD2 1 
ATOM   2372  N  N   . GLY B 1 50  ? 80.255  76.303  82.787  1.00 30.45  ? 50  GLY B N   1 
ATOM   2373  C  CA  . GLY B 1 50  ? 80.238  75.244  83.780  1.00 31.65  ? 50  GLY B CA  1 
ATOM   2374  C  C   . GLY B 1 50  ? 80.773  73.907  83.317  1.00 31.54  ? 50  GLY B C   1 
ATOM   2375  O  O   . GLY B 1 50  ? 80.644  72.923  84.054  1.00 34.11  ? 50  GLY B O   1 
ATOM   2376  N  N   . GLY B 1 51  ? 81.375  73.838  82.127  1.00 31.63  ? 51  GLY B N   1 
ATOM   2377  C  CA  . GLY B 1 51  ? 81.946  72.603  81.611  1.00 29.78  ? 51  GLY B CA  1 
ATOM   2378  C  C   . GLY B 1 51  ? 80.908  71.547  81.240  1.00 34.12  ? 51  GLY B C   1 
ATOM   2379  O  O   . GLY B 1 51  ? 79.721  71.823  81.064  1.00 30.79  ? 51  GLY B O   1 
ATOM   2380  N  N   . CYS B 1 52  ? 81.395  70.317  81.087  1.00 33.16  ? 52  CYS B N   1 
ATOM   2381  C  CA  . CYS B 1 52  ? 80.520  69.173  80.866  1.00 32.95  ? 52  CYS B CA  1 
ATOM   2382  C  C   . CYS B 1 52  ? 79.702  68.870  82.119  1.00 35.14  ? 52  CYS B C   1 
ATOM   2383  O  O   . CYS B 1 52  ? 80.159  69.067  83.247  1.00 31.51  ? 52  CYS B O   1 
ATOM   2384  C  CB  . CYS B 1 52  ? 81.342  67.944  80.497  1.00 32.02  ? 52  CYS B CB  1 
ATOM   2385  S  SG  . CYS B 1 52  ? 82.588  68.216  79.245  1.00 36.97  ? 52  CYS B SG  1 
ATOM   2386  N  N   . ALA B 1 53  ? 78.479  68.381  81.916  1.00 34.31  ? 53  ALA B N   1 
ATOM   2387  C  CA  . ALA B 1 53  ? 77.642  68.011  83.055  1.00 36.49  ? 53  ALA B CA  1 
ATOM   2388  C  C   . ALA B 1 53  ? 78.334  66.937  83.892  1.00 40.29  ? 53  ALA B C   1 
ATOM   2389  O  O   . ALA B 1 53  ? 78.997  66.039  83.361  1.00 36.45  ? 53  ALA B O   1 
ATOM   2390  C  CB  . ALA B 1 53  ? 76.276  67.509  82.583  1.00 35.88  ? 53  ALA B CB  1 
ATOM   2391  N  N   . VAL B 1 54  ? 78.188  67.042  85.215  1.00 38.89  ? 54  VAL B N   1 
ATOM   2392  C  CA  . VAL B 1 54  ? 78.829  66.076  86.104  1.00 41.35  ? 54  VAL B CA  1 
ATOM   2393  C  C   . VAL B 1 54  ? 78.354  64.664  85.787  1.00 46.00  ? 54  VAL B C   1 
ATOM   2394  O  O   . VAL B 1 54  ? 79.107  63.696  85.956  1.00 47.83  ? 54  VAL B O   1 
ATOM   2395  C  CB  . VAL B 1 54  ? 78.572  66.448  87.578  1.00 43.58  ? 54  VAL B CB  1 
ATOM   2396  C  CG1 . VAL B 1 54  ? 77.081  66.447  87.886  1.00 39.73  ? 54  VAL B CG1 1 
ATOM   2397  C  CG2 . VAL B 1 54  ? 79.339  65.516  88.510  1.00 44.23  ? 54  VAL B CG2 1 
ATOM   2398  N  N   . GLU B 1 55  ? 77.122  64.528  85.279  1.00 44.00  ? 55  GLU B N   1 
ATOM   2399  C  CA  . GLU B 1 55  ? 76.588  63.220  84.903  1.00 42.06  ? 55  GLU B CA  1 
ATOM   2400  C  C   . GLU B 1 55  ? 77.522  62.485  83.947  1.00 47.13  ? 55  GLU B C   1 
ATOM   2401  O  O   . GLU B 1 55  ? 77.555  61.249  83.932  1.00 48.79  ? 55  GLU B O   1 
ATOM   2402  C  CB  . GLU B 1 55  ? 75.193  63.395  84.278  1.00 38.67  ? 55  GLU B CB  1 
ATOM   2403  C  CG  . GLU B 1 55  ? 74.037  63.697  85.271  1.00 39.66  ? 55  GLU B CG  1 
ATOM   2404  C  CD  . GLU B 1 55  ? 73.897  65.180  85.680  1.00 40.85  ? 55  GLU B CD  1 
ATOM   2405  O  OE1 . GLU B 1 55  ? 74.788  66.006  85.368  1.00 42.11  ? 55  GLU B OE1 1 
ATOM   2406  O  OE2 . GLU B 1 55  ? 72.880  65.526  86.323  1.00 38.92  ? 55  GLU B OE2 1 
ATOM   2407  N  N   . CYS B 1 56  ? 78.303  63.229  83.156  1.00 49.03  ? 56  CYS B N   1 
ATOM   2408  C  CA  . CYS B 1 56  ? 79.267  62.626  82.241  1.00 44.44  ? 56  CYS B CA  1 
ATOM   2409  C  C   . CYS B 1 56  ? 80.414  61.932  82.962  1.00 51.74  ? 56  CYS B C   1 
ATOM   2410  O  O   . CYS B 1 56  ? 81.088  61.094  82.351  1.00 50.52  ? 56  CYS B O   1 
ATOM   2411  C  CB  . CYS B 1 56  ? 79.860  63.689  81.319  1.00 44.98  ? 56  CYS B CB  1 
ATOM   2412  S  SG  . CYS B 1 56  ? 78.659  64.556  80.348  1.00 45.30  ? 56  CYS B SG  1 
ATOM   2413  N  N   . ALA B 1 57  ? 80.689  62.298  84.221  1.00 48.05  ? 57  ALA B N   1 
ATOM   2414  C  CA  . ALA B 1 57  ? 81.753  61.621  84.957  1.00 53.33  ? 57  ALA B CA  1 
ATOM   2415  C  C   . ALA B 1 57  ? 81.351  60.197  85.324  1.00 57.16  ? 57  ALA B C   1 
ATOM   2416  O  O   . ALA B 1 57  ? 82.206  59.302  85.367  1.00 59.55  ? 57  ALA B O   1 
ATOM   2417  C  CB  . ALA B 1 57  ? 82.122  62.416  86.208  1.00 52.34  ? 57  ALA B CB  1 
ATOM   2418  N  N   . SER B 1 58  ? 80.060  59.965  85.561  1.00 56.24  ? 58  SER B N   1 
ATOM   2419  C  CA  . SER B 1 58  ? 79.550  58.635  85.882  1.00 56.30  ? 58  SER B CA  1 
ATOM   2420  C  C   . SER B 1 58  ? 79.098  57.879  84.631  1.00 56.31  ? 58  SER B C   1 
ATOM   2421  O  O   . SER B 1 58  ? 79.591  56.784  84.351  1.00 57.11  ? 58  SER B O   1 
ATOM   2422  C  CB  . SER B 1 58  ? 78.395  58.751  86.885  1.00 56.28  ? 58  SER B CB  1 
ATOM   2423  O  OG  . SER B 1 58  ? 78.877  59.056  88.182  1.00 61.03  ? 58  SER B OG  1 
ATOM   2424  N  N   . ASP B 1 59  ? 78.174  58.457  83.862  1.00 55.13  ? 59  ASP B N   1 
ATOM   2425  C  CA  . ASP B 1 59  ? 77.482  57.744  82.786  1.00 53.82  ? 59  ASP B CA  1 
ATOM   2426  C  C   . ASP B 1 59  ? 77.481  58.599  81.524  1.00 53.64  ? 59  ASP B C   1 
ATOM   2427  O  O   . ASP B 1 59  ? 76.459  59.181  81.144  1.00 48.24  ? 59  ASP B O   1 
ATOM   2428  C  CB  . ASP B 1 59  ? 76.062  57.376  83.230  1.00 55.03  ? 59  ASP B CB  1 
ATOM   2429  C  CG  . ASP B 1 59  ? 75.327  56.510  82.226  1.00 58.93  ? 59  ASP B CG  1 
ATOM   2430  O  OD1 . ASP B 1 59  ? 75.968  55.649  81.591  1.00 58.98  ? 59  ASP B OD1 1 
ATOM   2431  O  OD2 . ASP B 1 59  ? 74.106  56.690  82.067  1.00 63.60  ? 59  ASP B OD2 1 
ATOM   2432  N  N   . PRO B 1 60  ? 78.632  58.698  80.841  1.00 54.15  ? 60  PRO B N   1 
ATOM   2433  C  CA  . PRO B 1 60  ? 78.701  59.477  79.594  1.00 51.24  ? 60  PRO B CA  1 
ATOM   2434  C  C   . PRO B 1 60  ? 77.710  59.005  78.542  1.00 51.42  ? 60  PRO B C   1 
ATOM   2435  O  O   . PRO B 1 60  ? 76.908  59.805  78.044  1.00 44.23  ? 60  PRO B O   1 
ATOM   2436  C  CB  . PRO B 1 60  ? 80.143  59.259  79.111  1.00 52.90  ? 60  PRO B CB  1 
ATOM   2437  C  CG  . PRO B 1 60  ? 80.901  58.808  80.304  1.00 46.60  ? 60  PRO B CG  1 
ATOM   2438  C  CD  . PRO B 1 60  ? 79.931  58.108  81.207  1.00 53.01  ? 60  PRO B CD  1 
ATOM   2439  N  N   . LYS B 1 61  ? 77.770  57.713  78.192  1.00 49.97  ? 61  LYS B N   1 
ATOM   2440  C  CA  . LYS B 1 61  ? 76.903  57.180  77.142  1.00 50.69  ? 61  LYS B CA  1 
ATOM   2441  C  C   . LYS B 1 61  ? 75.434  57.388  77.486  1.00 51.56  ? 61  LYS B C   1 
ATOM   2442  O  O   . LYS B 1 61  ? 74.615  57.687  76.607  1.00 47.22  ? 61  LYS B O   1 
ATOM   2443  C  CB  . LYS B 1 61  ? 77.209  55.696  76.914  1.00 54.21  ? 61  LYS B CB  1 
ATOM   2444  C  CG  . LYS B 1 61  ? 76.425  55.034  75.778  1.00 60.82  ? 61  LYS B CG  1 
ATOM   2445  C  CD  . LYS B 1 61  ? 77.263  54.853  74.512  1.00 64.52  ? 61  LYS B CD  1 
ATOM   2446  C  CE  . LYS B 1 61  ? 76.446  54.211  73.387  1.00 72.65  ? 61  LYS B CE  1 
ATOM   2447  N  NZ  . LYS B 1 61  ? 75.994  55.191  72.348  1.00 64.30  ? 61  LYS B NZ  1 
ATOM   2448  N  N   . GLY B 1 62  ? 75.084  57.261  78.764  1.00 50.66  ? 62  GLY B N   1 
ATOM   2449  C  CA  . GLY B 1 62  ? 73.700  57.460  79.155  1.00 52.87  ? 62  GLY B CA  1 
ATOM   2450  C  C   . GLY B 1 62  ? 73.237  58.896  78.993  1.00 52.14  ? 62  GLY B C   1 
ATOM   2451  O  O   . GLY B 1 62  ? 72.110  59.147  78.552  1.00 55.93  ? 62  GLY B O   1 
ATOM   2452  N  N   . TYR B 1 63  ? 74.095  59.860  79.339  1.00 45.34  ? 63  TYR B N   1 
ATOM   2453  C  CA  . TYR B 1 63  ? 73.665  61.255  79.376  1.00 45.17  ? 63  TYR B CA  1 
ATOM   2454  C  C   . TYR B 1 63  ? 73.828  61.966  78.033  1.00 43.33  ? 63  TYR B C   1 
ATOM   2455  O  O   . TYR B 1 63  ? 72.965  62.760  77.659  1.00 41.13  ? 63  TYR B O   1 
ATOM   2456  C  CB  . TYR B 1 63  ? 74.426  62.014  80.470  1.00 41.95  ? 63  TYR B CB  1 
ATOM   2457  C  CG  . TYR B 1 63  ? 73.753  63.303  80.915  1.00 44.05  ? 63  TYR B CG  1 
ATOM   2458  C  CD1 . TYR B 1 63  ? 72.551  63.279  81.627  1.00 41.96  ? 63  TYR B CD1 1 
ATOM   2459  C  CD2 . TYR B 1 63  ? 74.319  64.549  80.626  1.00 42.81  ? 63  TYR B CD2 1 
ATOM   2460  C  CE1 . TYR B 1 63  ? 71.928  64.465  82.038  1.00 42.85  ? 63  TYR B CE1 1 
ATOM   2461  C  CE2 . TYR B 1 63  ? 73.699  65.742  81.036  1.00 42.48  ? 63  TYR B CE2 1 
ATOM   2462  C  CZ  . TYR B 1 63  ? 72.508  65.694  81.744  1.00 41.17  ? 63  TYR B CZ  1 
ATOM   2463  O  OH  . TYR B 1 63  ? 71.895  66.873  82.150  1.00 37.01  ? 63  TYR B OH  1 
ATOM   2464  N  N   . TRP B 1 64  ? 74.917  61.701  77.308  1.00 40.69  ? 64  TRP B N   1 
ATOM   2465  C  CA  . TRP B 1 64  ? 75.210  62.340  76.026  1.00 40.46  ? 64  TRP B CA  1 
ATOM   2466  C  C   . TRP B 1 64  ? 74.785  61.525  74.811  1.00 43.56  ? 64  TRP B C   1 
ATOM   2467  O  O   . TRP B 1 64  ? 74.575  62.107  73.740  1.00 39.16  ? 64  TRP B O   1 
ATOM   2468  C  CB  . TRP B 1 64  ? 76.710  62.624  75.894  1.00 34.71  ? 64  TRP B CB  1 
ATOM   2469  C  CG  . TRP B 1 64  ? 77.152  63.866  76.582  1.00 36.50  ? 64  TRP B CG  1 
ATOM   2470  C  CD1 . TRP B 1 64  ? 76.409  64.656  77.412  1.00 37.68  ? 64  TRP B CD1 1 
ATOM   2471  C  CD2 . TRP B 1 64  ? 78.450  64.466  76.507  1.00 32.31  ? 64  TRP B CD2 1 
ATOM   2472  N  NE1 . TRP B 1 64  ? 77.166  65.714  77.857  1.00 37.36  ? 64  TRP B NE1 1 
ATOM   2473  C  CE2 . TRP B 1 64  ? 78.420  65.625  77.310  1.00 33.92  ? 64  TRP B CE2 1 
ATOM   2474  C  CE3 . TRP B 1 64  ? 79.631  64.139  75.833  1.00 31.35  ? 64  TRP B CE3 1 
ATOM   2475  C  CZ2 . TRP B 1 64  ? 79.526  66.452  77.466  1.00 33.18  ? 64  TRP B CZ2 1 
ATOM   2476  C  CZ3 . TRP B 1 64  ? 80.727  64.958  75.982  1.00 35.50  ? 64  TRP B CZ3 1 
ATOM   2477  C  CH2 . TRP B 1 64  ? 80.672  66.102  76.798  1.00 37.32  ? 64  TRP B CH2 1 
ATOM   2478  N  N   . GLY B 1 65  ? 74.699  60.196  74.926  1.00 45.21  ? 65  GLY B N   1 
ATOM   2479  C  CA  . GLY B 1 65  ? 74.307  59.388  73.784  1.00 42.86  ? 65  GLY B CA  1 
ATOM   2480  C  C   . GLY B 1 65  ? 75.381  59.299  72.708  1.00 43.98  ? 65  GLY B C   1 
ATOM   2481  O  O   . GLY B 1 65  ? 76.582  59.422  72.966  1.00 46.69  ? 65  GLY B O   1 
ATOM   2482  N  N   . ASP B 1 66  ? 74.918  59.114  71.470  1.00 41.00  ? 66  ASP B N   1 
ATOM   2483  C  CA  . ASP B 1 66  ? 75.793  58.746  70.358  1.00 43.46  ? 66  ASP B CA  1 
ATOM   2484  C  C   . ASP B 1 66  ? 76.944  59.723  70.151  1.00 44.68  ? 66  ASP B C   1 
ATOM   2485  O  O   . ASP B 1 66  ? 77.994  59.328  69.628  1.00 46.73  ? 66  ASP B O   1 
ATOM   2486  C  CB  . ASP B 1 66  ? 74.981  58.641  69.066  1.00 48.50  ? 66  ASP B CB  1 
ATOM   2487  C  CG  . ASP B 1 66  ? 74.063  57.434  69.050  1.00 55.78  ? 66  ASP B CG  1 
ATOM   2488  O  OD1 . ASP B 1 66  ? 74.082  56.657  70.034  1.00 58.11  ? 66  ASP B OD1 1 
ATOM   2489  O  OD2 . ASP B 1 66  ? 73.307  57.272  68.062  1.00 58.31  ? 66  ASP B OD2 1 
ATOM   2490  N  N   . ILE B 1 67  ? 76.770  60.994  70.533  1.00 43.06  ? 67  ILE B N   1 
ATOM   2491  C  CA  . ILE B 1 67  ? 77.818  61.990  70.308  1.00 46.18  ? 67  ILE B CA  1 
ATOM   2492  C  C   . ILE B 1 67  ? 79.136  61.570  70.961  1.00 49.11  ? 67  ILE B C   1 
ATOM   2493  O  O   . ILE B 1 67  ? 80.217  61.964  70.498  1.00 48.34  ? 67  ILE B O   1 
ATOM   2494  C  CB  . ILE B 1 67  ? 77.347  63.380  70.797  1.00 45.17  ? 67  ILE B CB  1 
ATOM   2495  C  CG1 . ILE B 1 67  ? 78.341  64.477  70.389  1.00 39.36  ? 67  ILE B CG1 1 
ATOM   2496  C  CG2 . ILE B 1 67  ? 77.091  63.391  72.296  1.00 38.63  ? 67  ILE B CG2 1 
ATOM   2497  C  CD1 . ILE B 1 67  ? 78.410  64.722  68.913  1.00 43.48  ? 67  ILE B CD1 1 
ATOM   2498  N  N   . THR B 1 68  ? 79.075  60.740  72.015  1.00 45.29  ? 68  THR B N   1 
ATOM   2499  C  CA  . THR B 1 68  ? 80.286  60.252  72.674  1.00 48.60  ? 68  THR B CA  1 
ATOM   2500  C  C   . THR B 1 68  ? 81.226  59.515  71.722  1.00 50.45  ? 68  THR B C   1 
ATOM   2501  O  O   . THR B 1 68  ? 82.433  59.458  71.984  1.00 48.81  ? 68  THR B O   1 
ATOM   2502  C  CB  . THR B 1 68  ? 79.937  59.325  73.847  1.00 48.64  ? 68  THR B CB  1 
ATOM   2503  O  OG1 . THR B 1 68  ? 79.189  58.203  73.369  1.00 51.65  ? 68  THR B OG1 1 
ATOM   2504  C  CG2 . THR B 1 68  ? 79.131  60.055  74.911  1.00 44.30  ? 68  THR B CG2 1 
ATOM   2505  N  N   . SER B 1 69  ? 80.714  58.943  70.629  1.00 50.15  ? 69  SER B N   1 
ATOM   2506  C  CA  . SER B 1 69  ? 81.612  58.369  69.632  1.00 48.60  ? 69  SER B CA  1 
ATOM   2507  C  C   . SER B 1 69  ? 82.442  59.430  68.931  1.00 50.05  ? 69  SER B C   1 
ATOM   2508  O  O   . SER B 1 69  ? 83.398  59.083  68.228  1.00 47.93  ? 69  SER B O   1 
ATOM   2509  C  CB  . SER B 1 69  ? 80.829  57.563  68.593  1.00 48.65  ? 69  SER B CB  1 
ATOM   2510  O  OG  . SER B 1 69  ? 79.692  58.279  68.137  1.00 49.94  ? 69  SER B OG  1 
ATOM   2511  N  N   . VAL B 1 70  ? 82.102  60.702  69.096  1.00 47.40  ? 70  VAL B N   1 
ATOM   2512  C  CA  . VAL B 1 70  ? 82.909  61.796  68.578  1.00 49.41  ? 70  VAL B CA  1 
ATOM   2513  C  C   . VAL B 1 70  ? 83.693  62.479  69.692  1.00 46.59  ? 70  VAL B C   1 
ATOM   2514  O  O   . VAL B 1 70  ? 84.891  62.730  69.561  1.00 43.42  ? 70  VAL B O   1 
ATOM   2515  C  CB  . VAL B 1 70  ? 82.018  62.805  67.821  1.00 48.66  ? 70  VAL B CB  1 
ATOM   2516  C  CG1 . VAL B 1 70  ? 82.879  63.796  67.069  1.00 46.70  ? 70  VAL B CG1 1 
ATOM   2517  C  CG2 . VAL B 1 70  ? 81.079  62.069  66.875  1.00 49.53  ? 70  VAL B CG2 1 
ATOM   2518  N  N   . TYR B 1 71  ? 83.025  62.777  70.799  1.00 43.04  ? 71  TYR B N   1 
ATOM   2519  C  CA  . TYR B 1 71  ? 83.617  63.497  71.921  1.00 44.81  ? 71  TYR B CA  1 
ATOM   2520  C  C   . TYR B 1 71  ? 83.473  62.597  73.141  1.00 44.83  ? 71  TYR B C   1 
ATOM   2521  O  O   . TYR B 1 71  ? 82.380  62.477  73.702  1.00 45.38  ? 71  TYR B O   1 
ATOM   2522  C  CB  . TYR B 1 71  ? 82.935  64.846  72.137  1.00 44.93  ? 71  TYR B CB  1 
ATOM   2523  C  CG  . TYR B 1 71  ? 83.068  65.811  70.972  1.00 43.89  ? 71  TYR B CG  1 
ATOM   2524  C  CD1 . TYR B 1 71  ? 84.250  66.489  70.739  1.00 41.15  ? 71  TYR B CD1 1 
ATOM   2525  C  CD2 . TYR B 1 71  ? 81.996  66.043  70.109  1.00 46.51  ? 71  TYR B CD2 1 
ATOM   2526  C  CE1 . TYR B 1 71  ? 84.366  67.375  69.673  1.00 49.34  ? 71  TYR B CE1 1 
ATOM   2527  C  CE2 . TYR B 1 71  ? 82.099  66.920  69.042  1.00 39.85  ? 71  TYR B CE2 1 
ATOM   2528  C  CZ  . TYR B 1 71  ? 83.282  67.582  68.825  1.00 45.66  ? 71  TYR B CZ  1 
ATOM   2529  O  OH  . TYR B 1 71  ? 83.384  68.457  67.767  1.00 48.65  ? 71  TYR B OH  1 
ATOM   2530  N  N   . TRP B 1 72  ? 84.561  61.945  73.543  1.00 42.71  ? 72  TRP B N   1 
ATOM   2531  C  CA  . TRP B 1 72  ? 84.524  61.140  74.749  1.00 44.51  ? 72  TRP B CA  1 
ATOM   2532  C  C   . TRP B 1 72  ? 84.967  61.989  75.931  1.00 41.95  ? 72  TRP B C   1 
ATOM   2533  O  O   . TRP B 1 72  ? 86.084  62.527  75.912  1.00 43.72  ? 72  TRP B O   1 
ATOM   2534  C  CB  . TRP B 1 72  ? 85.407  59.903  74.628  1.00 46.03  ? 72  TRP B CB  1 
ATOM   2535  C  CG  . TRP B 1 72  ? 85.223  59.022  75.829  1.00 48.28  ? 72  TRP B CG  1 
ATOM   2536  C  CD1 . TRP B 1 72  ? 86.003  58.985  76.957  1.00 45.57  ? 72  TRP B CD1 1 
ATOM   2537  C  CD2 . TRP B 1 72  ? 84.138  58.113  76.063  1.00 50.21  ? 72  TRP B CD2 1 
ATOM   2538  N  NE1 . TRP B 1 72  ? 85.483  58.088  77.863  1.00 47.71  ? 72  TRP B NE1 1 
ATOM   2539  C  CE2 . TRP B 1 72  ? 84.341  57.538  77.338  1.00 50.91  ? 72  TRP B CE2 1 
ATOM   2540  C  CE3 . TRP B 1 72  ? 83.023  57.719  75.312  1.00 51.07  ? 72  TRP B CE3 1 
ATOM   2541  C  CZ2 . TRP B 1 72  ? 83.471  56.590  77.874  1.00 46.15  ? 72  TRP B CZ2 1 
ATOM   2542  C  CZ3 . TRP B 1 72  ? 82.156  56.779  75.850  1.00 47.99  ? 72  TRP B CZ3 1 
ATOM   2543  C  CH2 . TRP B 1 72  ? 82.386  56.227  77.117  1.00 48.72  ? 72  TRP B CH2 1 
ATOM   2544  N  N   . PRO B 1 73  ? 84.146  62.144  76.947  1.00 41.00  ? 73  PRO B N   1 
ATOM   2545  C  CA  . PRO B 1 73  ? 84.520  62.997  78.079  1.00 44.00  ? 73  PRO B CA  1 
ATOM   2546  C  C   . PRO B 1 73  ? 85.228  62.227  79.185  1.00 42.70  ? 73  PRO B C   1 
ATOM   2547  O  O   . PRO B 1 73  ? 84.776  61.148  79.576  1.00 46.07  ? 73  PRO B O   1 
ATOM   2548  C  CB  . PRO B 1 73  ? 83.168  63.540  78.554  1.00 42.89  ? 73  PRO B CB  1 
ATOM   2549  C  CG  . PRO B 1 73  ? 82.180  62.467  78.183  1.00 38.94  ? 73  PRO B CG  1 
ATOM   2550  C  CD  . PRO B 1 73  ? 82.746  61.688  77.027  1.00 42.53  ? 73  PRO B CD  1 
ATOM   2551  N  N   . VAL B 1 74  ? 86.312  62.788  79.716  1.00 43.03  ? 74  VAL B N   1 
ATOM   2552  C  CA  . VAL B 1 74  ? 87.138  62.152  80.743  1.00 43.37  ? 74  VAL B CA  1 
ATOM   2553  C  C   . VAL B 1 74  ? 87.164  63.099  81.936  1.00 44.45  ? 74  VAL B C   1 
ATOM   2554  O  O   . VAL B 1 74  ? 87.984  64.027  81.977  1.00 42.97  ? 74  VAL B O   1 
ATOM   2555  C  CB  . VAL B 1 74  ? 88.560  61.860  80.242  1.00 41.10  ? 74  VAL B CB  1 
ATOM   2556  C  CG1 . VAL B 1 74  ? 89.432  61.305  81.370  1.00 40.42  ? 74  VAL B CG1 1 
ATOM   2557  C  CG2 . VAL B 1 74  ? 88.534  60.911  79.054  1.00 44.39  ? 74  VAL B CG2 1 
ATOM   2558  N  N   . MET B 1 75  ? 86.288  62.876  82.914  1.00 42.42  ? 75  MET B N   1 
ATOM   2559  C  CA  . MET B 1 75  ? 86.247  63.762  84.067  1.00 44.45  ? 75  MET B CA  1 
ATOM   2560  C  C   . MET B 1 75  ? 85.803  62.991  85.307  1.00 46.25  ? 75  MET B C   1 
ATOM   2561  O  O   . MET B 1 75  ? 85.122  61.966  85.220  1.00 49.17  ? 75  MET B O   1 
ATOM   2562  C  CB  . MET B 1 75  ? 85.314  64.960  83.826  1.00 42.13  ? 75  MET B CB  1 
ATOM   2563  C  CG  . MET B 1 75  ? 83.851  64.614  83.873  1.00 44.31  ? 75  MET B CG  1 
ATOM   2564  S  SD  . MET B 1 75  ? 82.708  65.989  83.582  1.00 44.54  ? 75  MET B SD  1 
ATOM   2565  C  CE  . MET B 1 75  ? 82.430  66.643  85.231  1.00 35.80  ? 75  MET B CE  1 
ATOM   2566  N  N   . ARG B 1 76  ? 86.198  63.507  86.469  1.00 46.78  ? 76  ARG B N   1 
ATOM   2567  C  CA  . ARG B 1 76  ? 85.809  62.989  87.777  1.00 49.95  ? 76  ARG B CA  1 
ATOM   2568  C  C   . ARG B 1 76  ? 84.616  63.762  88.334  1.00 50.22  ? 76  ARG B C   1 
ATOM   2569  O  O   . ARG B 1 76  ? 84.384  64.923  87.985  1.00 49.52  ? 76  ARG B O   1 
ATOM   2570  C  CB  . ARG B 1 76  ? 86.981  63.079  88.768  1.00 51.40  ? 76  ARG B CB  1 
ATOM   2571  C  CG  . ARG B 1 76  ? 88.223  62.269  88.382  1.00 53.63  ? 76  ARG B CG  1 
ATOM   2572  C  CD  . ARG B 1 76  ? 89.373  62.446  89.392  1.00 56.56  ? 76  ARG B CD  1 
ATOM   2573  N  NE  . ARG B 1 76  ? 89.584  63.838  89.784  1.00 60.62  ? 76  ARG B NE  1 
ATOM   2574  C  CZ  . ARG B 1 76  ? 90.253  64.730  89.062  1.00 60.54  ? 76  ARG B CZ  1 
ATOM   2575  N  NH1 . ARG B 1 76  ? 90.808  64.406  87.904  1.00 57.36  ? 76  ARG B NH1 1 
ATOM   2576  N  NH2 . ARG B 1 76  ? 90.365  65.981  89.511  1.00 55.05  ? 76  ARG B NH2 1 
ATOM   2577  N  N   . ILE B 1 77  ? 83.870  63.108  89.231  1.00 50.96  ? 77  ILE B N   1 
ATOM   2578  C  CA  . ILE B 1 77  ? 82.718  63.761  89.854  1.00 51.58  ? 77  ILE B CA  1 
ATOM   2579  C  C   . ILE B 1 77  ? 83.147  65.057  90.530  1.00 55.66  ? 77  ILE B C   1 
ATOM   2580  O  O   . ILE B 1 77  ? 82.421  66.064  90.504  1.00 52.68  ? 77  ILE B O   1 
ATOM   2581  C  CB  . ILE B 1 77  ? 82.004  62.829  90.858  1.00 53.03  ? 77  ILE B CB  1 
ATOM   2582  C  CG1 . ILE B 1 77  ? 81.238  61.671  90.187  1.00 61.13  ? 77  ILE B CG1 1 
ATOM   2583  C  CG2 . ILE B 1 77  ? 81.023  63.629  91.722  1.00 54.34  ? 77  ILE B CG2 1 
ATOM   2584  C  CD1 . ILE B 1 77  ? 82.023  60.735  89.269  1.00 58.36  ? 77  ILE B CD1 1 
ATOM   2585  N  N   . GLU B 1 78  ? 84.338  65.057  91.139  1.00 53.93  ? 78  GLU B N   1 
ATOM   2586  C  CA  . GLU B 1 78  ? 84.829  66.244  91.828  1.00 52.32  ? 78  GLU B CA  1 
ATOM   2587  C  C   . GLU B 1 78  ? 84.963  67.430  90.892  1.00 47.48  ? 78  GLU B C   1 
ATOM   2588  O  O   . GLU B 1 78  ? 84.962  68.574  91.356  1.00 48.49  ? 78  GLU B O   1 
ATOM   2589  C  CB  . GLU B 1 78  ? 86.189  65.983  92.495  1.00 46.82  ? 78  GLU B CB  1 
ATOM   2590  C  CG  . GLU B 1 78  ? 86.245  64.822  93.487  1.00 65.30  ? 78  GLU B CG  1 
ATOM   2591  C  CD  . GLU B 1 78  ? 85.957  63.460  92.864  1.00 64.27  ? 78  GLU B CD  1 
ATOM   2592  O  OE1 . GLU B 1 78  ? 86.808  62.968  92.088  1.00 60.87  ? 78  GLU B OE1 1 
ATOM   2593  O  OE2 . GLU B 1 78  ? 84.880  62.891  93.147  1.00 63.68  ? 78  GLU B OE2 1 
ATOM   2594  N  N   . GLU B 1 79  ? 85.088  67.183  89.591  1.00 48.54  ? 79  GLU B N   1 
ATOM   2595  C  CA  . GLU B 1 79  ? 85.256  68.263  88.631  1.00 46.92  ? 79  GLU B CA  1 
ATOM   2596  C  C   . GLU B 1 79  ? 83.936  68.912  88.234  1.00 45.09  ? 79  GLU B C   1 
ATOM   2597  O  O   . GLU B 1 79  ? 83.959  69.995  87.637  1.00 38.10  ? 79  GLU B O   1 
ATOM   2598  C  CB  . GLU B 1 79  ? 85.977  67.746  87.389  1.00 43.56  ? 79  GLU B CB  1 
ATOM   2599  C  CG  . GLU B 1 79  ? 87.220  66.934  87.688  1.00 45.45  ? 79  GLU B CG  1 
ATOM   2600  C  CD  . GLU B 1 79  ? 88.124  66.793  86.480  1.00 44.85  ? 79  GLU B CD  1 
ATOM   2601  O  OE1 . GLU B 1 79  ? 88.958  67.695  86.247  1.00 41.81  ? 79  GLU B OE1 1 
ATOM   2602  O  OE2 . GLU B 1 79  ? 87.993  65.781  85.755  1.00 46.62  ? 79  GLU B OE2 1 
ATOM   2603  N  N   . GLY B 1 80  ? 82.802  68.284  88.553  1.00 40.33  ? 80  GLY B N   1 
ATOM   2604  C  CA  . GLY B 1 80  ? 81.496  68.880  88.332  1.00 42.71  ? 80  GLY B CA  1 
ATOM   2605  C  C   . GLY B 1 80  ? 81.410  70.270  88.925  1.00 43.18  ? 80  GLY B C   1 
ATOM   2606  O  O   . GLY B 1 80  ? 81.841  70.487  90.063  1.00 42.71  ? 80  GLY B O   1 
ATOM   2607  N  N   . CYS B 1 81  ? 80.855  71.220  88.162  1.00 37.89  ? 81  CYS B N   1 
ATOM   2608  C  CA  . CYS B 1 81  ? 81.000  72.630  88.514  1.00 37.59  ? 81  CYS B CA  1 
ATOM   2609  C  C   . CYS B 1 81  ? 80.403  72.933  89.892  1.00 36.35  ? 81  CYS B C   1 
ATOM   2610  O  O   . CYS B 1 81  ? 80.964  73.725  90.656  1.00 35.84  ? 81  CYS B O   1 
ATOM   2611  C  CB  . CYS B 1 81  ? 80.376  73.514  87.421  1.00 33.99  ? 81  CYS B CB  1 
ATOM   2612  S  SG  . CYS B 1 81  ? 78.568  73.361  87.195  1.00 38.36  ? 81  CYS B SG  1 
ATOM   2613  N  N   . VAL B 1 82  ? 79.283  72.302  90.238  1.00 34.72  ? 82  VAL B N   1 
ATOM   2614  C  CA  . VAL B 1 82  ? 78.709  72.517  91.564  1.00 40.58  ? 82  VAL B CA  1 
ATOM   2615  C  C   . VAL B 1 82  ? 79.643  71.987  92.652  1.00 43.75  ? 82  VAL B C   1 
ATOM   2616  O  O   . VAL B 1 82  ? 79.853  72.635  93.689  1.00 41.29  ? 82  VAL B O   1 
ATOM   2617  C  CB  . VAL B 1 82  ? 77.327  71.857  91.653  1.00 41.61  ? 82  VAL B CB  1 
ATOM   2618  C  CG1 . VAL B 1 82  ? 76.812  71.903  93.092  1.00 42.66  ? 82  VAL B CG1 1 
ATOM   2619  C  CG2 . VAL B 1 82  ? 76.382  72.532  90.711  1.00 39.91  ? 82  VAL B CG2 1 
ATOM   2620  N  N   . GLN B 1 83  ? 80.213  70.803  92.431  1.00 40.26  ? 83  GLN B N   1 
ATOM   2621  C  CA  . GLN B 1 83  ? 81.099  70.201  93.418  1.00 43.09  ? 83  GLN B CA  1 
ATOM   2622  C  C   . GLN B 1 83  ? 82.350  71.056  93.622  1.00 42.03  ? 83  GLN B C   1 
ATOM   2623  O  O   . GLN B 1 83  ? 82.653  71.471  94.746  1.00 41.22  ? 83  GLN B O   1 
ATOM   2624  C  CB  . GLN B 1 83  ? 81.438  68.776  92.976  1.00 43.82  ? 83  GLN B CB  1 
ATOM   2625  C  CG  . GLN B 1 83  ? 80.216  67.816  92.951  1.00 51.01  ? 83  GLN B CG  1 
ATOM   2626  C  CD  . GLN B 1 83  ? 79.218  68.054  91.779  1.00 52.46  ? 83  GLN B CD  1 
ATOM   2627  O  OE1 . GLN B 1 83  ? 79.420  68.919  90.912  1.00 47.33  ? 83  GLN B OE1 1 
ATOM   2628  N  NE2 . GLN B 1 83  ? 78.143  67.269  91.761  1.00 51.50  ? 83  GLN B NE2 1 
ATOM   2629  N  N   . ALA B 1 84  ? 83.050  71.387  92.528  1.00 39.10  ? 84  ALA B N   1 
ATOM   2630  C  CA  . ALA B 1 84  ? 84.259  72.207  92.616  1.00 39.14  ? 84  ALA B CA  1 
ATOM   2631  C  C   . ALA B 1 84  ? 84.020  73.548  93.312  1.00 39.51  ? 84  ALA B C   1 
ATOM   2632  O  O   . ALA B 1 84  ? 84.927  74.069  93.967  1.00 40.53  ? 84  ALA B O   1 
ATOM   2633  C  CB  . ALA B 1 84  ? 84.831  72.441  91.218  1.00 36.72  ? 84  ALA B CB  1 
ATOM   2634  N  N   . LEU B 1 85  ? 82.825  74.132  93.173  1.00 39.90  ? 85  LEU B N   1 
ATOM   2635  C  CA  . LEU B 1 85  ? 82.557  75.415  93.822  1.00 39.40  ? 85  LEU B CA  1 
ATOM   2636  C  C   . LEU B 1 85  ? 82.338  75.251  95.325  1.00 43.13  ? 85  LEU B C   1 
ATOM   2637  O  O   . LEU B 1 85  ? 82.817  76.073  96.117  1.00 40.77  ? 85  LEU B O   1 
ATOM   2638  C  CB  . LEU B 1 85  ? 81.349  76.103  93.179  1.00 38.05  ? 85  LEU B CB  1 
ATOM   2639  C  CG  . LEU B 1 85  ? 81.565  76.779  91.816  1.00 41.57  ? 85  LEU B CG  1 
ATOM   2640  C  CD1 . LEU B 1 85  ? 80.354  77.633  91.445  1.00 36.14  ? 85  LEU B CD1 1 
ATOM   2641  C  CD2 . LEU B 1 85  ? 82.838  77.615  91.807  1.00 33.76  ? 85  LEU B CD2 1 
ATOM   2642  N  N   . LYS B 1 86  ? 81.579  74.225  95.730  1.00 42.46  ? 86  LYS B N   1 
ATOM   2643  C  CA  . LYS B 1 86  ? 81.439  73.904  97.148  1.00 44.77  ? 86  LYS B CA  1 
ATOM   2644  C  C   . LYS B 1 86  ? 82.807  73.782  97.802  1.00 41.05  ? 86  LYS B C   1 
ATOM   2645  O  O   . LYS B 1 86  ? 83.122  74.496  98.759  1.00 41.67  ? 86  LYS B O   1 
ATOM   2646  C  CB  . LYS B 1 86  ? 80.651  72.601  97.321  1.00 42.84  ? 86  LYS B CB  1 
ATOM   2647  C  CG  . LYS B 1 86  ? 79.173  72.710  97.001  1.00 48.09  ? 86  LYS B CG  1 
ATOM   2648  C  CD  . LYS B 1 86  ? 78.388  71.576  97.642  1.00 48.13  ? 86  LYS B CD  1 
ATOM   2649  C  CE  . LYS B 1 86  ? 77.725  70.684  96.622  1.00 45.86  ? 86  LYS B CE  1 
ATOM   2650  N  NZ  . LYS B 1 86  ? 76.240  70.764  96.767  1.00 49.65  ? 86  LYS B NZ  1 
ATOM   2651  N  N   . ALA B 1 87  ? 83.654  72.911  97.244  1.00 39.15  ? 87  ALA B N   1 
ATOM   2652  C  CA  . ALA B 1 87  ? 85.010  72.729  97.735  1.00 40.86  ? 87  ALA B CA  1 
ATOM   2653  C  C   . ALA B 1 87  ? 85.785  74.036  97.767  1.00 46.57  ? 87  ALA B C   1 
ATOM   2654  O  O   . ALA B 1 87  ? 86.697  74.203  98.587  1.00 48.84  ? 87  ALA B O   1 
ATOM   2655  C  CB  . ALA B 1 87  ? 85.731  71.702  96.862  1.00 36.95  ? 87  ALA B CB  1 
ATOM   2656  N  N   . PHE B 1 88  ? 85.441  74.971  96.889  1.00 43.93  ? 88  PHE B N   1 
ATOM   2657  C  CA  . PHE B 1 88  ? 86.113  76.260  96.870  1.00 47.06  ? 88  PHE B CA  1 
ATOM   2658  C  C   . PHE B 1 88  ? 85.534  77.214  97.908  1.00 46.85  ? 88  PHE B C   1 
ATOM   2659  O  O   . PHE B 1 88  ? 86.196  78.189  98.280  1.00 50.74  ? 88  PHE B O   1 
ATOM   2660  C  CB  . PHE B 1 88  ? 86.027  76.835  95.445  1.00 49.88  ? 88  PHE B CB  1 
ATOM   2661  C  CG  . PHE B 1 88  ? 86.538  78.239  95.306  1.00 49.50  ? 88  PHE B CG  1 
ATOM   2662  C  CD1 . PHE B 1 88  ? 85.686  79.324  95.476  1.00 49.91  ? 88  PHE B CD1 1 
ATOM   2663  C  CD2 . PHE B 1 88  ? 87.859  78.474  94.972  1.00 49.07  ? 88  PHE B CD2 1 
ATOM   2664  C  CE1 . PHE B 1 88  ? 86.147  80.616  95.339  1.00 50.04  ? 88  PHE B CE1 1 
ATOM   2665  C  CE2 . PHE B 1 88  ? 88.328  79.764  94.835  1.00 49.02  ? 88  PHE B CE2 1 
ATOM   2666  C  CZ  . PHE B 1 88  ? 87.468  80.837  95.015  1.00 51.67  ? 88  PHE B CZ  1 
ATOM   2667  N  N   . GLY B 1 89  ? 84.318  76.952  98.383  1.00 44.66  ? 89  GLY B N   1 
ATOM   2668  C  CA  . GLY B 1 89  ? 83.720  77.760  99.424  1.00 45.88  ? 89  GLY B CA  1 
ATOM   2669  C  C   . GLY B 1 89  ? 82.453  78.471  99.001  1.00 45.15  ? 89  GLY B C   1 
ATOM   2670  O  O   . GLY B 1 89  ? 81.977  79.356  99.713  1.00 47.80  ? 89  GLY B O   1 
ATOM   2671  N  N   . ILE B 1 90  ? 81.892  78.101  97.853  1.00 43.31  ? 90  ILE B N   1 
ATOM   2672  C  CA  . ILE B 1 90  ? 80.725  78.779  97.297  1.00 41.28  ? 90  ILE B CA  1 
ATOM   2673  C  C   . ILE B 1 90  ? 79.607  77.761  97.146  1.00 41.33  ? 90  ILE B C   1 
ATOM   2674  O  O   . ILE B 1 90  ? 79.737  76.793  96.385  1.00 42.35  ? 90  ILE B O   1 
ATOM   2675  C  CB  . ILE B 1 90  ? 81.036  79.447  95.949  1.00 44.30  ? 90  ILE B CB  1 
ATOM   2676  C  CG1 . ILE B 1 90  ? 81.944  80.661  96.156  1.00 43.41  ? 90  ILE B CG1 1 
ATOM   2677  C  CG2 . ILE B 1 90  ? 79.740  79.842  95.233  1.00 38.09  ? 90  ILE B CG2 1 
ATOM   2678  C  CD1 . ILE B 1 90  ? 82.515  81.221  94.869  1.00 39.66  ? 90  ILE B CD1 1 
ATOM   2679  N  N   . GLU B 1 91  ? 78.518  77.977  97.860  1.00 39.22  ? 91  GLU B N   1 
ATOM   2680  C  CA  . GLU B 1 91  ? 77.401  77.059  97.769  1.00 44.92  ? 91  GLU B CA  1 
ATOM   2681  C  C   . GLU B 1 91  ? 76.570  77.393  96.533  1.00 45.17  ? 91  GLU B C   1 
ATOM   2682  O  O   . GLU B 1 91  ? 76.598  78.531  96.052  1.00 44.73  ? 91  GLU B O   1 
ATOM   2683  C  CB  . GLU B 1 91  ? 76.552  77.140  99.038  1.00 49.87  ? 91  GLU B CB  1 
ATOM   2684  C  CG  . GLU B 1 91  ? 77.183  76.464  100.267 1.00 47.99  ? 91  GLU B CG  1 
ATOM   2685  C  CD  . GLU B 1 91  ? 77.343  74.959  100.103 1.00 49.74  ? 91  GLU B CD  1 
ATOM   2686  O  OE1 . GLU B 1 91  ? 76.376  74.300  99.651  1.00 50.08  ? 91  GLU B OE1 1 
ATOM   2687  O  OE2 . GLU B 1 91  ? 78.434  74.437  100.435 1.00 46.09  ? 91  GLU B OE2 1 
ATOM   2688  N  N   . PRO B 1 92  ? 75.823  76.416  95.997  1.00 44.22  ? 92  PRO B N   1 
ATOM   2689  C  CA  . PRO B 1 92  ? 75.078  76.654  94.743  1.00 42.86  ? 92  PRO B CA  1 
ATOM   2690  C  C   . PRO B 1 92  ? 74.181  77.881  94.774  1.00 43.71  ? 92  PRO B C   1 
ATOM   2691  O  O   . PRO B 1 92  ? 73.960  78.515  93.732  1.00 40.76  ? 92  PRO B O   1 
ATOM   2692  C  CB  . PRO B 1 92  ? 74.243  75.376  94.580  1.00 41.08  ? 92  PRO B CB  1 
ATOM   2693  C  CG  . PRO B 1 92  ? 74.926  74.342  95.398  1.00 43.83  ? 92  PRO B CG  1 
ATOM   2694  C  CD  . PRO B 1 92  ? 75.711  75.024  96.468  1.00 42.02  ? 92  PRO B CD  1 
ATOM   2695  N  N   . ALA B 1 93  ? 73.641  78.226  95.940  1.00 44.02  ? 93  ALA B N   1 
ATOM   2696  C  CA  . ALA B 1 93  ? 72.763  79.381  96.030  1.00 41.72  ? 93  ALA B CA  1 
ATOM   2697  C  C   . ALA B 1 93  ? 73.508  80.697  95.849  1.00 39.03  ? 93  ALA B C   1 
ATOM   2698  O  O   . ALA B 1 93  ? 72.871  81.707  95.538  1.00 42.21  ? 93  ALA B O   1 
ATOM   2699  C  CB  . ALA B 1 93  ? 72.027  79.372  97.374  1.00 42.45  ? 93  ALA B CB  1 
ATOM   2700  N  N   . ASP B 1 94  ? 74.834  80.715  96.023  1.00 38.24  ? 94  ASP B N   1 
ATOM   2701  C  CA  . ASP B 1 94  ? 75.606  81.957  96.004  1.00 41.50  ? 94  ASP B CA  1 
ATOM   2702  C  C   . ASP B 1 94  ? 76.124  82.317  94.608  1.00 39.43  ? 94  ASP B C   1 
ATOM   2703  O  O   . ASP B 1 94  ? 77.175  82.963  94.476  1.00 33.13  ? 94  ASP B O   1 
ATOM   2704  C  CB  . ASP B 1 94  ? 76.763  81.871  97.007  1.00 43.65  ? 94  ASP B CB  1 
ATOM   2705  C  CG  . ASP B 1 94  ? 76.283  81.525  98.417  1.00 52.60  ? 94  ASP B CG  1 
ATOM   2706  O  OD1 . ASP B 1 94  ? 75.235  82.088  98.836  1.00 48.11  ? 94  ASP B OD1 1 
ATOM   2707  O  OD2 . ASP B 1 94  ? 76.943  80.689  99.093  1.00 48.21  ? 94  ASP B OD2 1 
ATOM   2708  N  N   . VAL B 1 95  ? 75.399  81.936  93.561  1.00 40.92  ? 95  VAL B N   1 
ATOM   2709  C  CA  . VAL B 1 95  ? 75.718  82.304  92.189  1.00 32.45  ? 95  VAL B CA  1 
ATOM   2710  C  C   . VAL B 1 95  ? 74.579  83.171  91.669  1.00 33.90  ? 95  VAL B C   1 
ATOM   2711  O  O   . VAL B 1 95  ? 73.431  82.716  91.589  1.00 35.32  ? 95  VAL B O   1 
ATOM   2712  C  CB  . VAL B 1 95  ? 75.923  81.063  91.308  1.00 35.15  ? 95  VAL B CB  1 
ATOM   2713  C  CG1 . VAL B 1 95  ? 76.057  81.453  89.837  1.00 27.83  ? 95  VAL B CG1 1 
ATOM   2714  C  CG2 . VAL B 1 95  ? 77.157  80.297  91.777  1.00 33.62  ? 95  VAL B CG2 1 
ATOM   2715  N  N   . ARG B 1 96  ? 74.897  84.419  91.320  1.00 31.77  ? 96  ARG B N   1 
ATOM   2716  C  CA  . ARG B 1 96  ? 73.887  85.343  90.817  1.00 31.48  ? 96  ARG B CA  1 
ATOM   2717  C  C   . ARG B 1 96  ? 73.584  85.133  89.334  1.00 30.13  ? 96  ARG B C   1 
ATOM   2718  O  O   . ARG B 1 96  ? 72.420  85.187  88.925  1.00 34.25  ? 96  ARG B O   1 
ATOM   2719  C  CB  . ARG B 1 96  ? 74.343  86.773  91.045  1.00 28.43  ? 96  ARG B CB  1 
ATOM   2720  C  CG  . ARG B 1 96  ? 73.260  87.756  90.828  1.00 29.06  ? 96  ARG B CG  1 
ATOM   2721  C  CD  . ARG B 1 96  ? 73.795  89.119  91.101  1.00 29.69  ? 96  ARG B CD  1 
ATOM   2722  N  NE  . ARG B 1 96  ? 72.800  90.130  90.808  1.00 26.99  ? 96  ARG B NE  1 
ATOM   2723  C  CZ  . ARG B 1 96  ? 72.871  91.373  91.249  1.00 33.12  ? 96  ARG B CZ  1 
ATOM   2724  N  NH1 . ARG B 1 96  ? 73.888  91.776  91.993  1.00 29.49  ? 96  ARG B NH1 1 
ATOM   2725  N  NH2 . ARG B 1 96  ? 71.891  92.226  90.952  1.00 30.18  ? 96  ARG B NH2 1 
ATOM   2726  N  N   . TYR B 1 97  ? 74.611  84.917  88.511  1.00 33.33  ? 97  TYR B N   1 
ATOM   2727  C  CA  . TYR B 1 97  ? 74.459  84.823  87.063  1.00 28.28  ? 97  TYR B CA  1 
ATOM   2728  C  C   . TYR B 1 97  ? 75.219  83.614  86.543  1.00 29.18  ? 97  TYR B C   1 
ATOM   2729  O  O   . TYR B 1 97  ? 76.346  83.355  86.974  1.00 29.50  ? 97  TYR B O   1 
ATOM   2730  C  CB  . TYR B 1 97  ? 75.010  86.068  86.350  1.00 28.94  ? 97  TYR B CB  1 
ATOM   2731  C  CG  . TYR B 1 97  ? 74.371  87.377  86.712  1.00 29.26  ? 97  TYR B CG  1 
ATOM   2732  C  CD1 . TYR B 1 97  ? 73.044  87.646  86.376  1.00 28.27  ? 97  TYR B CD1 1 
ATOM   2733  C  CD2 . TYR B 1 97  ? 75.095  88.360  87.372  1.00 29.33  ? 97  TYR B CD2 1 
ATOM   2734  C  CE1 . TYR B 1 97  ? 72.462  88.844  86.695  1.00 25.57  ? 97  TYR B CE1 1 
ATOM   2735  C  CE2 . TYR B 1 97  ? 74.521  89.565  87.696  1.00 26.65  ? 97  TYR B CE2 1 
ATOM   2736  C  CZ  . TYR B 1 97  ? 73.204  89.804  87.353  1.00 29.82  ? 97  TYR B CZ  1 
ATOM   2737  O  OH  . TYR B 1 97  ? 72.632  91.016  87.671  1.00 25.71  ? 97  TYR B OH  1 
ATOM   2738  N  N   . VAL B 1 98  ? 74.602  82.886  85.611  1.00 28.39  ? 98  VAL B N   1 
ATOM   2739  C  CA  . VAL B 1 98  ? 75.288  81.922  84.759  1.00 25.93  ? 98  VAL B CA  1 
ATOM   2740  C  C   . VAL B 1 98  ? 75.305  82.486  83.337  1.00 29.38  ? 98  VAL B C   1 
ATOM   2741  O  O   . VAL B 1 98  ? 74.248  82.777  82.757  1.00 27.21  ? 98  VAL B O   1 
ATOM   2742  C  CB  . VAL B 1 98  ? 74.620  80.538  84.798  1.00 28.67  ? 98  VAL B CB  1 
ATOM   2743  C  CG1 . VAL B 1 98  ? 75.213  79.638  83.719  1.00 23.78  ? 98  VAL B CG1 1 
ATOM   2744  C  CG2 . VAL B 1 98  ? 74.798  79.895  86.168  1.00 28.56  ? 98  VAL B CG2 1 
ATOM   2745  N  N   . LEU B 1 99  ? 76.499  82.673  82.784  1.00 28.20  ? 99  LEU B N   1 
ATOM   2746  C  CA  . LEU B 1 99  ? 76.658  83.169  81.424  1.00 23.50  ? 99  LEU B CA  1 
ATOM   2747  C  C   . LEU B 1 99  ? 76.992  82.008  80.494  1.00 26.24  ? 99  LEU B C   1 
ATOM   2748  O  O   . LEU B 1 99  ? 77.762  81.104  80.854  1.00 26.38  ? 99  LEU B O   1 
ATOM   2749  C  CB  . LEU B 1 99  ? 77.759  84.222  81.368  1.00 26.22  ? 99  LEU B CB  1 
ATOM   2750  C  CG  . LEU B 1 99  ? 77.734  85.222  82.517  1.00 23.18  ? 99  LEU B CG  1 
ATOM   2751  C  CD1 . LEU B 1 99  ? 78.877  86.233  82.368  1.00 24.75  ? 99  LEU B CD1 1 
ATOM   2752  C  CD2 . LEU B 1 99  ? 76.402  85.950  82.538  1.00 23.80  ? 99  LEU B CD2 1 
ATOM   2753  N  N   . HIS B 1 100 ? 76.415  82.022  79.298  1.00 20.41  ? 100 HIS B N   1 
ATOM   2754  C  CA  . HIS B 1 100 ? 76.669  80.971  78.332  1.00 21.24  ? 100 HIS B CA  1 
ATOM   2755  C  C   . HIS B 1 100 ? 77.308  81.569  77.085  1.00 23.85  ? 100 HIS B C   1 
ATOM   2756  O  O   . HIS B 1 100 ? 76.712  82.428  76.415  1.00 20.87  ? 100 HIS B O   1 
ATOM   2757  C  CB  . HIS B 1 100 ? 75.382  80.203  78.009  1.00 21.47  ? 100 HIS B CB  1 
ATOM   2758  C  CG  . HIS B 1 100 ? 75.048  79.153  79.025  1.00 27.93  ? 100 HIS B CG  1 
ATOM   2759  N  ND1 . HIS B 1 100 ? 75.883  78.085  79.289  1.00 24.25  ? 100 HIS B ND1 1 
ATOM   2760  C  CD2 . HIS B 1 100 ? 73.988  79.016  79.857  1.00 25.28  ? 100 HIS B CD2 1 
ATOM   2761  C  CE1 . HIS B 1 100 ? 75.348  77.334  80.232  1.00 25.94  ? 100 HIS B CE1 1 
ATOM   2762  N  NE2 . HIS B 1 100 ? 74.193  77.870  80.585  1.00 25.43  ? 100 HIS B NE2 1 
ATOM   2763  N  N   . SER B 1 101 ? 78.536  81.137  76.802  1.00 23.30  ? 101 SER B N   1 
ATOM   2764  C  CA  . SER B 1 101 ? 79.128  81.364  75.491  1.00 22.88  ? 101 SER B CA  1 
ATOM   2765  C  C   . SER B 1 101 ? 78.214  80.826  74.393  1.00 22.44  ? 101 SER B C   1 
ATOM   2766  O  O   . SER B 1 101 ? 77.923  81.510  73.407  1.00 22.29  ? 101 SER B O   1 
ATOM   2767  C  CB  . SER B 1 101 ? 80.491  80.680  75.435  1.00 26.98  ? 101 SER B CB  1 
ATOM   2768  O  OG  . SER B 1 101 ? 80.350  79.279  75.662  1.00 28.24  ? 101 SER B OG  1 
ATOM   2769  N  N   . HIS B 1 102 ? 77.761  79.594  74.557  1.00 25.59  ? 102 HIS B N   1 
ATOM   2770  C  CA  . HIS B 1 102 ? 76.835  78.903  73.665  1.00 24.34  ? 102 HIS B CA  1 
ATOM   2771  C  C   . HIS B 1 102 ? 76.318  77.698  74.439  1.00 23.57  ? 102 HIS B C   1 
ATOM   2772  O  O   . HIS B 1 102 ? 76.597  77.553  75.635  1.00 23.97  ? 102 HIS B O   1 
ATOM   2773  C  CB  . HIS B 1 102 ? 77.482  78.526  72.330  1.00 23.14  ? 102 HIS B CB  1 
ATOM   2774  C  CG  . HIS B 1 102 ? 78.704  77.668  72.446  1.00 28.65  ? 102 HIS B CG  1 
ATOM   2775  N  ND1 . HIS B 1 102 ? 79.671  77.848  73.418  1.00 27.96  ? 102 HIS B ND1 1 
ATOM   2776  C  CD2 . HIS B 1 102 ? 79.156  76.669  71.651  1.00 28.00  ? 102 HIS B CD2 1 
ATOM   2777  C  CE1 . HIS B 1 102 ? 80.650  76.978  73.228  1.00 28.41  ? 102 HIS B CE1 1 
ATOM   2778  N  NE2 . HIS B 1 102 ? 80.359  76.250  72.165  1.00 30.17  ? 102 HIS B NE2 1 
ATOM   2779  N  N   . LEU B 1 103 ? 75.532  76.843  73.782  1.00 23.31  ? 103 LEU B N   1 
ATOM   2780  C  CA  . LEU B 1 103 ? 74.828  75.797  74.513  1.00 25.28  ? 103 LEU B CA  1 
ATOM   2781  C  C   . LEU B 1 103 ? 75.249  74.405  74.073  1.00 26.08  ? 103 LEU B C   1 
ATOM   2782  O  O   . LEU B 1 103 ? 74.492  73.448  74.261  1.00 27.44  ? 103 LEU B O   1 
ATOM   2783  C  CB  . LEU B 1 103 ? 73.315  75.975  74.388  1.00 22.23  ? 103 LEU B CB  1 
ATOM   2784  C  CG  . LEU B 1 103 ? 72.808  77.214  75.123  1.00 24.24  ? 103 LEU B CG  1 
ATOM   2785  C  CD1 . LEU B 1 103 ? 71.288  77.404  74.951  1.00 22.04  ? 103 LEU B CD1 1 
ATOM   2786  C  CD2 . LEU B 1 103 ? 73.169  77.160  76.587  1.00 23.68  ? 103 LEU B CD2 1 
ATOM   2787  N  N   . HIS B 1 104 ? 76.492  74.285  73.636  1.00 24.50  ? 104 HIS B N   1 
ATOM   2788  C  CA  . HIS B 1 104 ? 77.035  72.949  73.291  1.00 26.91  ? 104 HIS B CA  1 
ATOM   2789  C  C   . HIS B 1 104 ? 77.219  72.099  74.554  1.00 29.36  ? 104 HIS B C   1 
ATOM   2790  O  O   . HIS B 1 104 ? 77.254  72.651  75.664  1.00 30.68  ? 104 HIS B O   1 
ATOM   2791  C  CB  . HIS B 1 104 ? 78.296  73.085  72.434  1.00 27.39  ? 104 HIS B CB  1 
ATOM   2792  C  CG  . HIS B 1 104 ? 78.025  73.457  71.023  1.00 26.69  ? 104 HIS B CG  1 
ATOM   2793  N  ND1 . HIS B 1 104 ? 79.029  73.812  70.154  1.00 26.23  ? 104 HIS B ND1 1 
ATOM   2794  C  CD2 . HIS B 1 104 ? 76.887  73.538  70.332  1.00 25.19  ? 104 HIS B CD2 1 
ATOM   2795  C  CE1 . HIS B 1 104 ? 78.499  74.105  68.983  1.00 31.63  ? 104 HIS B CE1 1 
ATOM   2796  N  NE2 . HIS B 1 104 ? 77.201  73.938  69.066  1.00 29.86  ? 104 HIS B NE2 1 
ATOM   2797  N  N   . LEU B 1 105 ? 77.346  70.791  74.382  1.00 28.42  ? 105 LEU B N   1 
ATOM   2798  C  CA  . LEU B 1 105 ? 77.410  69.813  75.505  1.00 32.26  ? 105 LEU B CA  1 
ATOM   2799  C  C   . LEU B 1 105 ? 78.516  70.109  76.527  1.00 32.97  ? 105 LEU B C   1 
ATOM   2800  O  O   . LEU B 1 105 ? 78.280  69.855  77.704  1.00 31.46  ? 105 LEU B O   1 
ATOM   2801  C  CB  . LEU B 1 105 ? 77.529  68.413  74.886  1.00 31.74  ? 105 LEU B CB  1 
ATOM   2802  C  CG  . LEU B 1 105 ? 78.808  68.004  74.148  1.00 32.62  ? 105 LEU B CG  1 
ATOM   2803  C  CD1 . LEU B 1 105 ? 78.661  66.584  73.636  1.00 35.46  ? 105 LEU B CD1 1 
ATOM   2804  C  CD2 . LEU B 1 105 ? 79.146  68.911  72.975  1.00 27.65  ? 105 LEU B CD2 1 
ATOM   2805  N  N   . ASP B 1 106 ? 79.650  70.647  76.093  1.00 30.61  ? 106 ASP B N   1 
ATOM   2806  C  CA  . ASP B 1 106 ? 80.786  70.923  77.005  1.00 30.17  ? 106 ASP B CA  1 
ATOM   2807  C  C   . ASP B 1 106 ? 80.691  72.339  77.597  1.00 34.36  ? 106 ASP B C   1 
ATOM   2808  O  O   . ASP B 1 106 ? 81.697  72.809  78.128  1.00 31.93  ? 106 ASP B O   1 
ATOM   2809  C  CB  . ASP B 1 106 ? 82.108  70.677  76.280  1.00 32.76  ? 106 ASP B CB  1 
ATOM   2810  C  CG  . ASP B 1 106 ? 82.237  71.364  74.933  1.00 35.34  ? 106 ASP B CG  1 
ATOM   2811  O  OD1 . ASP B 1 106 ? 81.258  71.358  74.173  1.00 35.34  ? 106 ASP B OD1 1 
ATOM   2812  O  OD2 . ASP B 1 106 ? 83.321  71.894  74.657  1.00 36.16  ? 106 ASP B OD2 1 
ATOM   2813  N  N   . HIS B 1 107 ? 79.528  72.982  77.505  1.00 29.25  ? 107 HIS B N   1 
ATOM   2814  C  CA  . HIS B 1 107 ? 79.344  74.360  78.026  1.00 28.99  ? 107 HIS B CA  1 
ATOM   2815  C  C   . HIS B 1 107 ? 77.975  74.512  78.706  1.00 27.48  ? 107 HIS B C   1 
ATOM   2816  O  O   . HIS B 1 107 ? 77.600  75.649  78.979  1.00 27.30  ? 107 HIS B O   1 
ATOM   2817  C  CB  . HIS B 1 107 ? 79.535  75.380  76.902  1.00 26.76  ? 107 HIS B CB  1 
ATOM   2818  C  CG  . HIS B 1 107 ? 80.820  75.251  76.161  1.00 30.52  ? 107 HIS B CG  1 
ATOM   2819  N  ND1 . HIS B 1 107 ? 81.938  75.993  76.465  1.00 26.31  ? 107 HIS B ND1 1 
ATOM   2820  C  CD2 . HIS B 1 107 ? 81.167  74.464  75.137  1.00 33.38  ? 107 HIS B CD2 1 
ATOM   2821  C  CE1 . HIS B 1 107 ? 82.919  75.654  75.646  1.00 30.33  ? 107 HIS B CE1 1 
ATOM   2822  N  NE2 . HIS B 1 107 ? 82.476  74.724  74.832  1.00 30.49  ? 107 HIS B NE2 1 
ATOM   2823  N  N   . THR B 1 108 ? 77.273  73.407  78.987  1.00 27.89  ? 108 THR B N   1 
ATOM   2824  C  CA  . THR B 1 108 ? 75.986  73.521  79.669  1.00 30.66  ? 108 THR B CA  1 
ATOM   2825  C  C   . THR B 1 108 ? 75.965  72.771  80.999  1.00 32.05  ? 108 THR B C   1 
ATOM   2826  O  O   . THR B 1 108 ? 74.881  72.451  81.510  1.00 30.52  ? 108 THR B O   1 
ATOM   2827  C  CB  . THR B 1 108 ? 74.849  73.042  78.758  1.00 32.19  ? 108 THR B CB  1 
ATOM   2828  O  OG1 . THR B 1 108 ? 75.198  71.794  78.139  1.00 28.15  ? 108 THR B OG1 1 
ATOM   2829  C  CG2 . THR B 1 108 ? 74.578  74.063  77.685  1.00 28.92  ? 108 THR B CG2 1 
ATOM   2830  N  N   . GLY B 1 109 ? 77.150  72.503  81.577  1.00 32.40  ? 109 GLY B N   1 
ATOM   2831  C  CA  . GLY B 1 109 ? 77.217  71.832  82.867  1.00 31.90  ? 109 GLY B CA  1 
ATOM   2832  C  C   . GLY B 1 109 ? 76.602  72.635  84.001  1.00 36.59  ? 109 GLY B C   1 
ATOM   2833  O  O   . GLY B 1 109 ? 76.093  72.061  84.969  1.00 32.14  ? 109 GLY B O   1 
ATOM   2834  N  N   . ALA B 1 110 ? 76.611  73.969  83.892  1.00 33.36  ? 110 ALA B N   1 
ATOM   2835  C  CA  . ALA B 1 110 ? 76.044  74.802  84.940  1.00 33.32  ? 110 ALA B CA  1 
ATOM   2836  C  C   . ALA B 1 110 ? 74.543  75.036  84.799  1.00 37.82  ? 110 ALA B C   1 
ATOM   2837  O  O   . ALA B 1 110 ? 73.908  75.412  85.789  1.00 33.85  ? 110 ALA B O   1 
ATOM   2838  C  CB  . ALA B 1 110 ? 76.753  76.154  84.978  1.00 30.58  ? 110 ALA B CB  1 
ATOM   2839  N  N   . THR B 1 111 ? 73.962  74.841  83.608  1.00 36.84  ? 111 THR B N   1 
ATOM   2840  C  CA  . THR B 1 111 ? 72.580  75.271  83.376  1.00 35.02  ? 111 THR B CA  1 
ATOM   2841  C  C   . THR B 1 111 ? 71.618  74.642  84.379  1.00 36.09  ? 111 THR B C   1 
ATOM   2842  O  O   . THR B 1 111 ? 71.470  73.416  84.432  1.00 33.63  ? 111 THR B O   1 
ATOM   2843  C  CB  . THR B 1 111 ? 72.115  74.928  81.960  1.00 29.89  ? 111 THR B CB  1 
ATOM   2844  O  OG1 . THR B 1 111 ? 73.167  75.182  81.018  1.00 32.64  ? 111 THR B OG1 1 
ATOM   2845  C  CG2 . THR B 1 111 ? 70.874  75.760  81.617  1.00 31.18  ? 111 THR B CG2 1 
ATOM   2846  N  N   . GLY B 1 112 ? 70.945  75.488  85.148  1.00 30.53  ? 112 GLY B N   1 
ATOM   2847  C  CA  . GLY B 1 112 ? 69.958  75.029  86.098  1.00 39.30  ? 112 GLY B CA  1 
ATOM   2848  C  C   . GLY B 1 112 ? 70.497  74.476  87.403  1.00 40.09  ? 112 GLY B C   1 
ATOM   2849  O  O   . GLY B 1 112 ? 69.697  74.157  88.288  1.00 39.77  ? 112 GLY B O   1 
ATOM   2850  N  N   . ARG B 1 113 ? 71.821  74.336  87.555  1.00 42.04  ? 113 ARG B N   1 
ATOM   2851  C  CA  . ARG B 1 113 ? 72.366  73.822  88.811  1.00 38.59  ? 113 ARG B CA  1 
ATOM   2852  C  C   . ARG B 1 113 ? 72.452  74.891  89.891  1.00 38.81  ? 113 ARG B C   1 
ATOM   2853  O  O   . ARG B 1 113 ? 72.794  74.580  91.034  1.00 39.06  ? 113 ARG B O   1 
ATOM   2854  C  CB  . ARG B 1 113 ? 73.764  73.227  88.641  1.00 36.50  ? 113 ARG B CB  1 
ATOM   2855  C  CG  . ARG B 1 113 ? 74.091  72.384  87.402  1.00 38.69  ? 113 ARG B CG  1 
ATOM   2856  C  CD  . ARG B 1 113 ? 72.946  71.605  86.815  1.00 41.51  ? 113 ARG B CD  1 
ATOM   2857  N  NE  . ARG B 1 113 ? 73.422  70.412  86.126  1.00 43.28  ? 113 ARG B NE  1 
ATOM   2858  C  CZ  . ARG B 1 113 ? 73.446  70.249  84.811  1.00 42.07  ? 113 ARG B CZ  1 
ATOM   2859  N  NH1 . ARG B 1 113 ? 73.096  71.229  83.981  1.00 39.92  ? 113 ARG B NH1 1 
ATOM   2860  N  NH2 . ARG B 1 113 ? 73.835  69.075  84.314  1.00 37.37  ? 113 ARG B NH2 1 
ATOM   2861  N  N   . PHE B 1 114 ? 72.168  76.137  89.565  1.00 38.39  ? 114 PHE B N   1 
ATOM   2862  C  CA  . PHE B 1 114 ? 72.258  77.216  90.538  1.00 37.42  ? 114 PHE B CA  1 
ATOM   2863  C  C   . PHE B 1 114 ? 70.896  77.885  90.626  1.00 36.09  ? 114 PHE B C   1 
ATOM   2864  O  O   . PHE B 1 114 ? 70.512  78.628  89.704  1.00 34.75  ? 114 PHE B O   1 
ATOM   2865  C  CB  . PHE B 1 114 ? 73.366  78.189  90.134  1.00 34.58  ? 114 PHE B CB  1 
ATOM   2866  C  CG  . PHE B 1 114 ? 74.710  77.519  89.979  1.00 34.36  ? 114 PHE B CG  1 
ATOM   2867  C  CD1 . PHE B 1 114 ? 75.538  77.324  91.081  1.00 34.42  ? 114 PHE B CD1 1 
ATOM   2868  C  CD2 . PHE B 1 114 ? 75.118  77.026  88.745  1.00 33.08  ? 114 PHE B CD2 1 
ATOM   2869  C  CE1 . PHE B 1 114 ? 76.783  76.687  90.941  1.00 40.40  ? 114 PHE B CE1 1 
ATOM   2870  C  CE2 . PHE B 1 114 ? 76.341  76.383  88.595  1.00 29.65  ? 114 PHE B CE2 1 
ATOM   2871  C  CZ  . PHE B 1 114 ? 77.181  76.211  89.699  1.00 35.83  ? 114 PHE B CZ  1 
ATOM   2872  N  N   . PRO B 1 115 ? 70.140  77.651  91.705  1.00 37.38  ? 115 PRO B N   1 
ATOM   2873  C  CA  . PRO B 1 115 ? 68.704  77.968  91.687  1.00 36.32  ? 115 PRO B CA  1 
ATOM   2874  C  C   . PRO B 1 115 ? 68.389  79.452  91.656  1.00 37.01  ? 115 PRO B C   1 
ATOM   2875  O  O   . PRO B 1 115 ? 67.286  79.811  91.229  1.00 36.48  ? 115 PRO B O   1 
ATOM   2876  C  CB  . PRO B 1 115 ? 68.178  77.329  92.979  1.00 37.61  ? 115 PRO B CB  1 
ATOM   2877  C  CG  . PRO B 1 115 ? 69.361  76.636  93.619  1.00 43.00  ? 115 PRO B CG  1 
ATOM   2878  C  CD  . PRO B 1 115 ? 70.595  77.179  93.025  1.00 35.76  ? 115 PRO B CD  1 
ATOM   2879  N  N   . ASN B 1 116 ? 69.291  80.327  92.098  1.00 32.25  ? 116 ASN B N   1 
ATOM   2880  C  CA  . ASN B 1 116 ? 69.008  81.759  92.118  1.00 35.76  ? 116 ASN B CA  1 
ATOM   2881  C  C   . ASN B 1 116 ? 69.616  82.507  90.936  1.00 36.81  ? 116 ASN B C   1 
ATOM   2882  O  O   . ASN B 1 116 ? 69.541  83.741  90.891  1.00 36.37  ? 116 ASN B O   1 
ATOM   2883  C  CB  . ASN B 1 116 ? 69.524  82.375  93.416  1.00 33.94  ? 116 ASN B CB  1 
ATOM   2884  C  CG  . ASN B 1 116 ? 69.052  81.620  94.623  1.00 40.25  ? 116 ASN B CG  1 
ATOM   2885  O  OD1 . ASN B 1 116 ? 67.867  81.344  94.757  1.00 36.31  ? 116 ASN B OD1 1 
ATOM   2886  N  ND2 . ASN B 1 116 ? 69.983  81.243  95.496  1.00 39.72  ? 116 ASN B ND2 1 
ATOM   2887  N  N   . ALA B 1 117 ? 70.237  81.802  90.003  1.00 32.65  ? 117 ALA B N   1 
ATOM   2888  C  CA  . ALA B 1 117 ? 71.075  82.438  88.997  1.00 35.56  ? 117 ALA B CA  1 
ATOM   2889  C  C   . ALA B 1 117 ? 70.239  82.768  87.767  1.00 33.59  ? 117 ALA B C   1 
ATOM   2890  O  O   . ALA B 1 117 ? 69.577  81.892  87.204  1.00 31.25  ? 117 ALA B O   1 
ATOM   2891  C  CB  . ALA B 1 117 ? 72.249  81.539  88.621  1.00 30.19  ? 117 ALA B CB  1 
ATOM   2892  N  N   . ILE B 1 118 ? 70.256  84.035  87.371  1.00 30.93  ? 118 ILE B N   1 
ATOM   2893  C  CA  . ILE B 1 118 ? 69.758  84.416  86.057  1.00 31.47  ? 118 ILE B CA  1 
ATOM   2894  C  C   . ILE B 1 118 ? 70.719  83.894  85.000  1.00 30.12  ? 118 ILE B C   1 
ATOM   2895  O  O   . ILE B 1 118 ? 71.938  84.083  85.108  1.00 31.80  ? 118 ILE B O   1 
ATOM   2896  C  CB  . ILE B 1 118 ? 69.605  85.941  85.981  1.00 31.95  ? 118 ILE B CB  1 
ATOM   2897  C  CG1 . ILE B 1 118 ? 68.420  86.382  86.851  1.00 36.77  ? 118 ILE B CG1 1 
ATOM   2898  C  CG2 . ILE B 1 118 ? 69.469  86.415  84.532  1.00 30.36  ? 118 ILE B CG2 1 
ATOM   2899  C  CD1 . ILE B 1 118 ? 68.171  87.877  86.819  1.00 35.48  ? 118 ILE B CD1 1 
ATOM   2900  N  N   . HIS B 1 119 ? 70.182  83.228  83.974  1.00 30.50  ? 119 HIS B N   1 
ATOM   2901  C  CA  . HIS B 1 119 ? 70.989  82.654  82.896  1.00 26.36  ? 119 HIS B CA  1 
ATOM   2902  C  C   . HIS B 1 119 ? 70.947  83.566  81.669  1.00 27.33  ? 119 HIS B C   1 
ATOM   2903  O  O   . HIS B 1 119 ? 69.871  83.805  81.107  1.00 26.55  ? 119 HIS B O   1 
ATOM   2904  C  CB  . HIS B 1 119 ? 70.496  81.257  82.517  1.00 23.44  ? 119 HIS B CB  1 
ATOM   2905  C  CG  . HIS B 1 119 ? 70.683  80.226  83.587  1.00 32.37  ? 119 HIS B CG  1 
ATOM   2906  N  ND1 . HIS B 1 119 ? 70.047  80.294  84.808  1.00 38.53  ? 119 HIS B ND1 1 
ATOM   2907  C  CD2 . HIS B 1 119 ? 71.420  79.089  83.610  1.00 29.54  ? 119 HIS B CD2 1 
ATOM   2908  C  CE1 . HIS B 1 119 ? 70.385  79.246  85.539  1.00 36.60  ? 119 HIS B CE1 1 
ATOM   2909  N  NE2 . HIS B 1 119 ? 71.214  78.498  84.832  1.00 34.22  ? 119 HIS B NE2 1 
ATOM   2910  N  N   . ILE B 1 120 ? 72.117  84.032  81.229  1.00 23.98  ? 120 ILE B N   1 
ATOM   2911  C  CA  . ILE B 1 120 ? 72.237  84.986  80.131  1.00 24.34  ? 120 ILE B CA  1 
ATOM   2912  C  C   . ILE B 1 120 ? 72.910  84.316  78.938  1.00 24.89  ? 120 ILE B C   1 
ATOM   2913  O  O   . ILE B 1 120 ? 74.035  83.817  79.050  1.00 20.13  ? 120 ILE B O   1 
ATOM   2914  C  CB  . ILE B 1 120 ? 73.019  86.243  80.548  1.00 23.12  ? 120 ILE B CB  1 
ATOM   2915  C  CG1 . ILE B 1 120 ? 72.568  86.742  81.931  1.00 22.58  ? 120 ILE B CG1 1 
ATOM   2916  C  CG2 . ILE B 1 120 ? 72.843  87.323  79.467  1.00 22.41  ? 120 ILE B CG2 1 
ATOM   2917  C  CD1 . ILE B 1 120 ? 73.092  88.124  82.291  1.00 23.56  ? 120 ILE B CD1 1 
ATOM   2918  N  N   . VAL B 1 121 ? 72.239  84.346  77.788  1.00 22.63  ? 121 VAL B N   1 
ATOM   2919  C  CA  . VAL B 1 121 ? 72.762  83.763  76.555  1.00 21.00  ? 121 VAL B CA  1 
ATOM   2920  C  C   . VAL B 1 121 ? 72.050  84.489  75.422  1.00 23.68  ? 121 VAL B C   1 
ATOM   2921  O  O   . VAL B 1 121 ? 71.006  85.117  75.637  1.00 17.68  ? 121 VAL B O   1 
ATOM   2922  C  CB  . VAL B 1 121 ? 72.528  82.224  76.525  1.00 20.88  ? 121 VAL B CB  1 
ATOM   2923  C  CG1 . VAL B 1 121 ? 71.056  81.912  76.310  1.00 20.26  ? 121 VAL B CG1 1 
ATOM   2924  C  CG2 . VAL B 1 121 ? 73.324  81.545  75.429  1.00 19.51  ? 121 VAL B CG2 1 
ATOM   2925  N  N   . ARG B 1 122 ? 72.627  84.430  74.208  1.00 19.95  ? 122 ARG B N   1 
ATOM   2926  C  CA  . ARG B 1 122 ? 71.975  85.036  73.044  1.00 21.37  ? 122 ARG B CA  1 
ATOM   2927  C  C   . ARG B 1 122 ? 70.679  84.306  72.711  1.00 21.59  ? 122 ARG B C   1 
ATOM   2928  O  O   . ARG B 1 122 ? 70.636  83.070  72.680  1.00 23.99  ? 122 ARG B O   1 
ATOM   2929  C  CB  . ARG B 1 122 ? 72.886  85.001  71.811  1.00 18.69  ? 122 ARG B CB  1 
ATOM   2930  C  CG  . ARG B 1 122 ? 74.074  85.947  71.871  1.00 21.89  ? 122 ARG B CG  1 
ATOM   2931  C  CD  . ARG B 1 122 ? 74.602  86.231  70.478  1.00 21.64  ? 122 ARG B CD  1 
ATOM   2932  N  NE  . ARG B 1 122 ? 73.601  86.846  69.618  1.00 27.02  ? 122 ARG B NE  1 
ATOM   2933  C  CZ  . ARG B 1 122 ? 73.854  87.291  68.392  1.00 29.28  ? 122 ARG B CZ  1 
ATOM   2934  N  NH1 . ARG B 1 122 ? 75.046  87.153  67.840  1.00 24.08  ? 122 ARG B NH1 1 
ATOM   2935  N  NH2 . ARG B 1 122 ? 72.895  87.913  67.713  1.00 28.98  ? 122 ARG B NH2 1 
ATOM   2936  N  N   . ARG B 1 123 ? 69.627  85.081  72.437  1.00 22.63  ? 123 ARG B N   1 
ATOM   2937  C  CA  . ARG B 1 123 ? 68.358  84.491  72.020  1.00 22.20  ? 123 ARG B CA  1 
ATOM   2938  C  C   . ARG B 1 123 ? 68.568  83.482  70.914  1.00 18.28  ? 123 ARG B C   1 
ATOM   2939  O  O   . ARG B 1 123 ? 68.003  82.381  70.943  1.00 17.15  ? 123 ARG B O   1 
ATOM   2940  C  CB  . ARG B 1 123 ? 67.366  85.555  71.538  1.00 23.24  ? 123 ARG B CB  1 
ATOM   2941  C  CG  . ARG B 1 123 ? 66.070  84.936  70.951  1.00 20.93  ? 123 ARG B CG  1 
ATOM   2942  C  CD  . ARG B 1 123 ? 64.936  85.946  70.805  1.00 18.25  ? 123 ARG B CD  1 
ATOM   2943  N  NE  . ARG B 1 123 ? 64.265  86.176  72.083  1.00 27.93  ? 123 ARG B NE  1 
ATOM   2944  C  CZ  . ARG B 1 123 ? 63.478  85.294  72.694  1.00 25.12  ? 123 ARG B CZ  1 
ATOM   2945  N  NH1 . ARG B 1 123 ? 63.183  84.123  72.145  1.00 22.71  ? 123 ARG B NH1 1 
ATOM   2946  N  NH2 . ARG B 1 123 ? 62.961  85.599  73.876  1.00 31.32  ? 123 ARG B NH2 1 
ATOM   2947  N  N   . CYS B 1 124 ? 69.367  83.847  69.916  1.00 21.48  ? 124 CYS B N   1 
ATOM   2948  C  CA  . CYS B 1 124 ? 69.423  82.993  68.741  1.00 24.80  ? 124 CYS B CA  1 
ATOM   2949  C  C   . CYS B 1 124 ? 70.153  81.689  69.035  1.00 25.07  ? 124 CYS B C   1 
ATOM   2950  O  O   . CYS B 1 124 ? 69.907  80.692  68.352  1.00 26.54  ? 124 CYS B O   1 
ATOM   2951  C  CB  . CYS B 1 124 ? 70.057  83.745  67.568  1.00 25.91  ? 124 CYS B CB  1 
ATOM   2952  S  SG  . CYS B 1 124 ? 71.807  84.051  67.735  1.00 31.41  ? 124 CYS B SG  1 
ATOM   2953  N  N   . GLU B 1 125 ? 70.992  81.659  70.073  1.00 23.45  ? 125 GLU B N   1 
ATOM   2954  C  CA  . GLU B 1 125 ? 71.546  80.388  70.529  1.00 23.45  ? 125 GLU B CA  1 
ATOM   2955  C  C   . GLU B 1 125 ? 70.491  79.536  71.227  1.00 23.12  ? 125 GLU B C   1 
ATOM   2956  O  O   . GLU B 1 125 ? 70.392  78.331  70.972  1.00 22.93  ? 125 GLU B O   1 
ATOM   2957  C  CB  . GLU B 1 125 ? 72.735  80.619  71.464  1.00 22.29  ? 125 GLU B CB  1 
ATOM   2958  C  CG  . GLU B 1 125 ? 73.361  79.328  71.950  1.00 20.40  ? 125 GLU B CG  1 
ATOM   2959  C  CD  . GLU B 1 125 ? 74.090  78.551  70.837  1.00 22.11  ? 125 GLU B CD  1 
ATOM   2960  O  OE1 . GLU B 1 125 ? 74.297  79.087  69.731  1.00 22.05  ? 125 GLU B OE1 1 
ATOM   2961  O  OE2 . GLU B 1 125 ? 74.467  77.393  71.076  1.00 26.43  ? 125 GLU B OE2 1 
ATOM   2962  N  N   . TYR B 1 126 ? 69.728  80.132  72.147  1.00 24.84  ? 126 TYR B N   1 
ATOM   2963  C  CA  . TYR B 1 126 ? 68.670  79.383  72.823  1.00 24.96  ? 126 TYR B CA  1 
ATOM   2964  C  C   . TYR B 1 126 ? 67.690  78.807  71.809  1.00 26.95  ? 126 TYR B C   1 
ATOM   2965  O  O   . TYR B 1 126 ? 67.317  77.629  71.881  1.00 26.31  ? 126 TYR B O   1 
ATOM   2966  C  CB  . TYR B 1 126 ? 67.939  80.286  73.819  1.00 26.37  ? 126 TYR B CB  1 
ATOM   2967  C  CG  . TYR B 1 126 ? 66.750  79.636  74.529  1.00 30.67  ? 126 TYR B CG  1 
ATOM   2968  C  CD1 . TYR B 1 126 ? 66.934  78.837  75.646  1.00 35.51  ? 126 TYR B CD1 1 
ATOM   2969  C  CD2 . TYR B 1 126 ? 65.449  79.821  74.068  1.00 31.76  ? 126 TYR B CD2 1 
ATOM   2970  C  CE1 . TYR B 1 126 ? 65.853  78.244  76.299  1.00 37.78  ? 126 TYR B CE1 1 
ATOM   2971  C  CE2 . TYR B 1 126 ? 64.369  79.239  74.703  1.00 32.05  ? 126 TYR B CE2 1 
ATOM   2972  C  CZ  . TYR B 1 126 ? 64.573  78.452  75.820  1.00 38.48  ? 126 TYR B CZ  1 
ATOM   2973  O  OH  . TYR B 1 126 ? 63.500  77.872  76.461  1.00 44.40  ? 126 TYR B OH  1 
ATOM   2974  N  N   . GLU B 1 127 ? 67.287  79.628  70.831  1.00 24.04  ? 127 GLU B N   1 
ATOM   2975  C  CA  . GLU B 1 127 ? 66.351  79.169  69.811  1.00 26.12  ? 127 GLU B CA  1 
ATOM   2976  C  C   . GLU B 1 127 ? 66.961  78.073  68.941  1.00 25.93  ? 127 GLU B C   1 
ATOM   2977  O  O   . GLU B 1 127 ? 66.296  77.078  68.640  1.00 23.67  ? 127 GLU B O   1 
ATOM   2978  C  CB  . GLU B 1 127 ? 65.888  80.355  68.965  1.00 23.69  ? 127 GLU B CB  1 
ATOM   2979  C  CG  . GLU B 1 127 ? 64.895  81.222  69.728  1.00 25.03  ? 127 GLU B CG  1 
ATOM   2980  C  CD  . GLU B 1 127 ? 64.478  82.471  68.979  1.00 25.48  ? 127 GLU B CD  1 
ATOM   2981  O  OE1 . GLU B 1 127 ? 65.143  82.836  67.986  1.00 23.80  ? 127 GLU B OE1 1 
ATOM   2982  O  OE2 . GLU B 1 127 ? 63.489  83.098  69.405  1.00 25.66  ? 127 GLU B OE2 1 
ATOM   2983  N  N   . TYR B 1 128 ? 68.220  78.237  68.529  1.00 25.95  ? 128 TYR B N   1 
ATOM   2984  C  CA  . TYR B 1 128 ? 68.871  77.198  67.736  1.00 24.21  ? 128 TYR B CA  1 
ATOM   2985  C  C   . TYR B 1 128 ? 69.040  75.904  68.532  1.00 25.36  ? 128 TYR B C   1 
ATOM   2986  O  O   . TYR B 1 128 ? 68.877  74.810  67.982  1.00 25.36  ? 128 TYR B O   1 
ATOM   2987  C  CB  . TYR B 1 128 ? 70.223  77.681  67.217  1.00 24.23  ? 128 TYR B CB  1 
ATOM   2988  C  CG  . TYR B 1 128 ? 70.789  76.719  66.192  1.00 24.62  ? 128 TYR B CG  1 
ATOM   2989  C  CD1 . TYR B 1 128 ? 70.296  76.704  64.892  1.00 25.38  ? 128 TYR B CD1 1 
ATOM   2990  C  CD2 . TYR B 1 128 ? 71.798  75.813  66.531  1.00 24.48  ? 128 TYR B CD2 1 
ATOM   2991  C  CE1 . TYR B 1 128 ? 70.795  75.811  63.932  1.00 24.58  ? 128 TYR B CE1 1 
ATOM   2992  C  CE2 . TYR B 1 128 ? 72.303  74.915  65.588  1.00 23.11  ? 128 TYR B CE2 1 
ATOM   2993  C  CZ  . TYR B 1 128 ? 71.782  74.928  64.290  1.00 22.06  ? 128 TYR B CZ  1 
ATOM   2994  O  OH  . TYR B 1 128 ? 72.235  74.073  63.342  1.00 24.07  ? 128 TYR B OH  1 
ATOM   2995  N  N   . ALA B 1 129 ? 69.356  76.006  69.827  1.00 24.21  ? 129 ALA B N   1 
ATOM   2996  C  CA  . ALA B 1 129 ? 69.530  74.792  70.624  1.00 26.42  ? 129 ALA B CA  1 
ATOM   2997  C  C   . ALA B 1 129 ? 68.232  73.996  70.687  1.00 25.82  ? 129 ALA B C   1 
ATOM   2998  O  O   . ALA B 1 129 ? 68.245  72.759  70.626  1.00 24.69  ? 129 ALA B O   1 
ATOM   2999  C  CB  . ALA B 1 129 ? 70.016  75.129  72.033  1.00 21.43  ? 129 ALA B CB  1 
ATOM   3000  N  N   . MET B 1 130 ? 67.101  74.696  70.779  1.00 24.65  ? 130 MET B N   1 
ATOM   3001  C  CA  . MET B 1 130 ? 65.792  74.050  70.810  1.00 27.47  ? 130 MET B CA  1 
ATOM   3002  C  C   . MET B 1 130 ? 65.380  73.442  69.471  1.00 26.66  ? 130 MET B C   1 
ATOM   3003  O  O   . MET B 1 130 ? 64.513  72.558  69.458  1.00 27.12  ? 130 MET B O   1 
ATOM   3004  C  CB  . MET B 1 130 ? 64.733  75.057  71.262  1.00 25.90  ? 130 MET B CB  1 
ATOM   3005  C  CG  . MET B 1 130 ? 64.937  75.490  72.697  1.00 30.00  ? 130 MET B CG  1 
ATOM   3006  S  SD  . MET B 1 130 ? 64.693  74.143  73.893  1.00 35.20  ? 130 MET B SD  1 
ATOM   3007  C  CE  . MET B 1 130 ? 63.135  74.660  74.597  1.00 35.88  ? 130 MET B CE  1 
ATOM   3008  N  N   . ALA B 1 131 ? 65.940  73.907  68.350  1.00 23.77  ? 131 ALA B N   1 
ATOM   3009  C  CA  . ALA B 1 131 ? 65.553  73.422  67.022  1.00 22.97  ? 131 ALA B CA  1 
ATOM   3010  C  C   . ALA B 1 131 ? 66.772  73.315  66.124  1.00 22.57  ? 131 ALA B C   1 
ATOM   3011  O  O   . ALA B 1 131 ? 66.890  74.037  65.128  1.00 20.03  ? 131 ALA B O   1 
ATOM   3012  C  CB  . ALA B 1 131 ? 64.509  74.343  66.397  1.00 22.32  ? 131 ALA B CB  1 
ATOM   3013  N  N   . PRO B 1 132 ? 67.704  72.420  66.446  1.00 24.18  ? 132 PRO B N   1 
ATOM   3014  C  CA  . PRO B 1 132 ? 68.954  72.336  65.679  1.00 22.48  ? 132 PRO B CA  1 
ATOM   3015  C  C   . PRO B 1 132 ? 68.788  71.555  64.377  1.00 23.52  ? 132 PRO B C   1 
ATOM   3016  O  O   . PRO B 1 132 ? 67.797  70.861  64.148  1.00 25.79  ? 132 PRO B O   1 
ATOM   3017  C  CB  . PRO B 1 132 ? 69.905  71.615  66.637  1.00 25.06  ? 132 PRO B CB  1 
ATOM   3018  C  CG  . PRO B 1 132 ? 68.958  70.723  67.488  1.00 23.77  ? 132 PRO B CG  1 
ATOM   3019  C  CD  . PRO B 1 132 ? 67.655  71.467  67.577  1.00 23.96  ? 132 PRO B CD  1 
ATOM   3020  N  N   . ASP B 1 133 ? 69.789  71.698  63.511  1.00 22.10  ? 133 ASP B N   1 
ATOM   3021  C  CA  . ASP B 1 133 ? 69.879  70.890  62.307  1.00 25.96  ? 133 ASP B CA  1 
ATOM   3022  C  C   . ASP B 1 133 ? 70.489  69.524  62.643  1.00 27.28  ? 133 ASP B C   1 
ATOM   3023  O  O   . ASP B 1 133 ? 71.010  69.302  63.740  1.00 30.24  ? 133 ASP B O   1 
ATOM   3024  C  CB  . ASP B 1 133 ? 70.712  71.608  61.238  1.00 25.12  ? 133 ASP B CB  1 
ATOM   3025  C  CG  . ASP B 1 133 ? 70.137  72.979  60.856  1.00 25.63  ? 133 ASP B CG  1 
ATOM   3026  O  OD1 . ASP B 1 133 ? 69.123  73.020  60.122  1.00 25.52  ? 133 ASP B OD1 1 
ATOM   3027  O  OD2 . ASP B 1 133 ? 70.719  74.020  61.255  1.00 25.72  ? 133 ASP B OD2 1 
ATOM   3028  N  N   . TRP B 1 134 ? 70.429  68.600  61.678  1.00 27.82  ? 134 TRP B N   1 
ATOM   3029  C  CA  . TRP B 1 134 ? 70.840  67.224  61.953  1.00 30.40  ? 134 TRP B CA  1 
ATOM   3030  C  C   . TRP B 1 134 ? 72.315  67.144  62.333  1.00 32.80  ? 134 TRP B C   1 
ATOM   3031  O  O   . TRP B 1 134 ? 72.690  66.337  63.194  1.00 33.39  ? 134 TRP B O   1 
ATOM   3032  C  CB  . TRP B 1 134 ? 70.530  66.309  60.758  1.00 30.72  ? 134 TRP B CB  1 
ATOM   3033  C  CG  . TRP B 1 134 ? 71.340  66.556  59.479  1.00 29.41  ? 134 TRP B CG  1 
ATOM   3034  C  CD1 . TRP B 1 134 ? 70.933  67.255  58.369  1.00 26.85  ? 134 TRP B CD1 1 
ATOM   3035  C  CD2 . TRP B 1 134 ? 72.655  66.065  59.177  1.00 30.06  ? 134 TRP B CD2 1 
ATOM   3036  N  NE1 . TRP B 1 134 ? 71.929  67.258  57.418  1.00 24.83  ? 134 TRP B NE1 1 
ATOM   3037  C  CE2 . TRP B 1 134 ? 72.990  66.528  57.883  1.00 27.15  ? 134 TRP B CE2 1 
ATOM   3038  C  CE3 . TRP B 1 134 ? 73.588  65.295  59.878  1.00 30.79  ? 134 TRP B CE3 1 
ATOM   3039  C  CZ2 . TRP B 1 134 ? 74.217  66.247  57.282  1.00 29.49  ? 134 TRP B CZ2 1 
ATOM   3040  C  CZ3 . TRP B 1 134 ? 74.808  65.024  59.283  1.00 32.23  ? 134 TRP B CZ3 1 
ATOM   3041  C  CH2 . TRP B 1 134 ? 75.110  65.495  57.994  1.00 29.36  ? 134 TRP B CH2 1 
ATOM   3042  N  N   . PHE B 1 135 ? 73.165  67.986  61.728  1.00 28.11  ? 135 PHE B N   1 
ATOM   3043  C  CA  . PHE B 1 135 ? 74.606  67.880  61.980  1.00 31.37  ? 135 PHE B CA  1 
ATOM   3044  C  C   . PHE B 1 135 ? 75.007  68.411  63.350  1.00 32.19  ? 135 PHE B C   1 
ATOM   3045  O  O   . PHE B 1 135 ? 76.110  68.112  63.813  1.00 32.20  ? 135 PHE B O   1 
ATOM   3046  C  CB  . PHE B 1 135 ? 75.409  68.610  60.893  1.00 28.26  ? 135 PHE B CB  1 
ATOM   3047  C  CG  . PHE B 1 135 ? 75.421  70.114  61.045  1.00 33.83  ? 135 PHE B CG  1 
ATOM   3048  C  CD1 . PHE B 1 135 ? 74.384  70.881  60.535  1.00 25.51  ? 135 PHE B CD1 1 
ATOM   3049  C  CD2 . PHE B 1 135 ? 76.470  70.761  61.703  1.00 32.47  ? 135 PHE B CD2 1 
ATOM   3050  C  CE1 . PHE B 1 135 ? 74.391  72.269  60.668  1.00 25.32  ? 135 PHE B CE1 1 
ATOM   3051  C  CE2 . PHE B 1 135 ? 76.475  72.141  61.845  1.00 30.95  ? 135 PHE B CE2 1 
ATOM   3052  C  CZ  . PHE B 1 135 ? 75.434  72.896  61.325  1.00 25.59  ? 135 PHE B CZ  1 
ATOM   3053  N  N   . SER B 1 136 ? 74.149  69.195  64.001  1.00 29.95  ? 136 SER B N   1 
ATOM   3054  C  CA  . SER B 1 136 ? 74.473  69.777  65.290  1.00 28.60  ? 136 SER B CA  1 
ATOM   3055  C  C   . SER B 1 136 ? 73.559  69.308  66.403  1.00 30.18  ? 136 SER B C   1 
ATOM   3056  O  O   . SER B 1 136 ? 73.796  69.670  67.560  1.00 31.66  ? 136 SER B O   1 
ATOM   3057  C  CB  . SER B 1 136 ? 74.421  71.310  65.223  1.00 30.63  ? 136 SER B CB  1 
ATOM   3058  O  OG  . SER B 1 136 ? 73.152  71.742  64.748  1.00 30.20  ? 136 SER B OG  1 
ATOM   3059  N  N   . ALA B 1 137 ? 72.514  68.534  66.099  1.00 27.39  ? 137 ALA B N   1 
ATOM   3060  C  CA  . ALA B 1 137 ? 71.581  68.132  67.152  1.00 29.58  ? 137 ALA B CA  1 
ATOM   3061  C  C   . ALA B 1 137 ? 72.288  67.370  68.263  1.00 31.54  ? 137 ALA B C   1 
ATOM   3062  O  O   . ALA B 1 137 ? 71.952  67.534  69.443  1.00 29.31  ? 137 ALA B O   1 
ATOM   3063  C  CB  . ALA B 1 137 ? 70.445  67.285  66.578  1.00 29.71  ? 137 ALA B CB  1 
ATOM   3064  N  N   . GLY B 1 138 ? 73.290  66.552  67.909  1.00 31.07  ? 138 GLY B N   1 
ATOM   3065  C  CA  . GLY B 1 138 ? 73.996  65.777  68.918  1.00 35.71  ? 138 GLY B CA  1 
ATOM   3066  C  C   . GLY B 1 138 ? 74.690  66.634  69.967  1.00 39.48  ? 138 GLY B C   1 
ATOM   3067  O  O   . GLY B 1 138 ? 74.782  66.242  71.141  1.00 37.48  ? 138 GLY B O   1 
ATOM   3068  N  N   . GLY B 1 139 ? 75.174  67.813  69.567  1.00 26.26  ? 139 GLY B N   1 
ATOM   3069  C  CA  . GLY B 1 139 ? 75.896  68.680  70.462  1.00 28.44  ? 139 GLY B CA  1 
ATOM   3070  C  C   . GLY B 1 139 ? 75.035  69.443  71.430  1.00 27.61  ? 139 GLY B C   1 
ATOM   3071  O  O   . GLY B 1 139 ? 75.582  70.134  72.289  1.00 28.88  ? 139 GLY B O   1 
ATOM   3072  N  N   . TYR B 1 140 ? 73.718  69.341  71.328  1.00 29.82  ? 140 TYR B N   1 
ATOM   3073  C  CA  . TYR B 1 140 ? 72.811  70.062  72.216  1.00 29.20  ? 140 TYR B CA  1 
ATOM   3074  C  C   . TYR B 1 140 ? 72.120  69.038  73.111  1.00 33.69  ? 140 TYR B C   1 
ATOM   3075  O  O   . TYR B 1 140 ? 71.489  68.103  72.604  1.00 33.39  ? 140 TYR B O   1 
ATOM   3076  C  CB  . TYR B 1 140 ? 71.801  70.901  71.412  1.00 25.82  ? 140 TYR B CB  1 
ATOM   3077  C  CG  . TYR B 1 140 ? 72.431  72.136  70.773  1.00 27.39  ? 140 TYR B CG  1 
ATOM   3078  C  CD1 . TYR B 1 140 ? 72.784  73.243  71.557  1.00 27.69  ? 140 TYR B CD1 1 
ATOM   3079  C  CD2 . TYR B 1 140 ? 72.687  72.196  69.399  1.00 23.15  ? 140 TYR B CD2 1 
ATOM   3080  C  CE1 . TYR B 1 140 ? 73.365  74.367  71.004  1.00 24.79  ? 140 TYR B CE1 1 
ATOM   3081  C  CE2 . TYR B 1 140 ? 73.271  73.334  68.819  1.00 22.65  ? 140 TYR B CE2 1 
ATOM   3082  C  CZ  . TYR B 1 140 ? 73.607  74.410  69.625  1.00 24.90  ? 140 TYR B CZ  1 
ATOM   3083  O  OH  . TYR B 1 140 ? 74.181  75.543  69.087  1.00 25.43  ? 140 TYR B OH  1 
ATOM   3084  N  N   . ILE B 1 141 ? 72.267  69.198  74.434  1.00 34.17  ? 141 ILE B N   1 
ATOM   3085  C  CA  . ILE B 1 141 ? 71.801  68.230  75.429  1.00 34.61  ? 141 ILE B CA  1 
ATOM   3086  C  C   . ILE B 1 141 ? 70.588  68.835  76.123  1.00 35.92  ? 141 ILE B C   1 
ATOM   3087  O  O   . ILE B 1 141 ? 70.730  69.655  77.039  1.00 31.75  ? 141 ILE B O   1 
ATOM   3088  C  CB  . ILE B 1 141 ? 72.892  67.866  76.449  1.00 34.69  ? 141 ILE B CB  1 
ATOM   3089  C  CG1 . ILE B 1 141 ? 74.204  67.476  75.764  1.00 34.54  ? 141 ILE B CG1 1 
ATOM   3090  C  CG2 . ILE B 1 141 ? 72.421  66.724  77.348  1.00 35.63  ? 141 ILE B CG2 1 
ATOM   3091  C  CD1 . ILE B 1 141 ? 74.100  66.267  74.845  1.00 34.02  ? 141 ILE B CD1 1 
ATOM   3092  N  N   . ARG B 1 142 ? 69.392  68.418  75.696  1.00 36.65  ? 142 ARG B N   1 
ATOM   3093  C  CA  . ARG B 1 142 ? 68.146  68.915  76.280  1.00 38.84  ? 142 ARG B CA  1 
ATOM   3094  C  C   . ARG B 1 142 ? 68.135  68.796  77.801  1.00 38.56  ? 142 ARG B C   1 
ATOM   3095  O  O   . ARG B 1 142 ? 67.638  69.689  78.499  1.00 32.83  ? 142 ARG B O   1 
ATOM   3096  C  CB  . ARG B 1 142 ? 66.962  68.139  75.705  1.00 43.21  ? 142 ARG B CB  1 
ATOM   3097  C  CG  . ARG B 1 142 ? 66.606  68.522  74.290  1.00 49.32  ? 142 ARG B CG  1 
ATOM   3098  C  CD  . ARG B 1 142 ? 65.637  69.671  74.290  1.00 50.93  ? 142 ARG B CD  1 
ATOM   3099  N  NE  . ARG B 1 142 ? 64.649  69.551  73.231  1.00 51.10  ? 142 ARG B NE  1 
ATOM   3100  C  CZ  . ARG B 1 142 ? 64.862  69.861  71.958  1.00 54.32  ? 142 ARG B CZ  1 
ATOM   3101  N  NH1 . ARG B 1 142 ? 66.034  70.329  71.540  1.00 51.43  ? 142 ARG B NH1 1 
ATOM   3102  N  NH2 . ARG B 1 142 ? 63.875  69.695  71.077  1.00 56.17  ? 142 ARG B NH2 1 
ATOM   3103  N  N   . ALA B 1 143 ? 68.662  67.688  78.332  1.00 36.86  ? 143 ALA B N   1 
ATOM   3104  C  CA  . ALA B 1 143 ? 68.614  67.457  79.769  1.00 34.08  ? 143 ALA B CA  1 
ATOM   3105  C  C   . ALA B 1 143 ? 69.369  68.529  80.544  1.00 39.07  ? 143 ALA B C   1 
ATOM   3106  O  O   . ALA B 1 143 ? 69.131  68.691  81.750  1.00 35.70  ? 143 ALA B O   1 
ATOM   3107  C  CB  . ALA B 1 143 ? 69.170  66.063  80.097  1.00 35.22  ? 143 ALA B CB  1 
ATOM   3108  N  N   . ASP B 1 144 ? 70.269  69.264  79.879  1.00 34.72  ? 144 ASP B N   1 
ATOM   3109  C  CA  . ASP B 1 144 ? 70.995  70.351  80.521  1.00 31.38  ? 144 ASP B CA  1 
ATOM   3110  C  C   . ASP B 1 144 ? 70.222  71.666  80.460  1.00 35.39  ? 144 ASP B C   1 
ATOM   3111  O  O   . ASP B 1 144 ? 69.900  72.237  81.504  1.00 35.04  ? 144 ASP B O   1 
ATOM   3112  C  CB  . ASP B 1 144 ? 72.383  70.509  79.893  1.00 33.64  ? 144 ASP B CB  1 
ATOM   3113  C  CG  . ASP B 1 144 ? 73.418  69.596  80.523  1.00 35.26  ? 144 ASP B CG  1 
ATOM   3114  O  OD1 . ASP B 1 144 ? 73.108  68.979  81.564  1.00 37.23  ? 144 ASP B OD1 1 
ATOM   3115  O  OD2 . ASP B 1 144 ? 74.546  69.491  79.989  1.00 35.88  ? 144 ASP B OD2 1 
ATOM   3116  N  N   . PHE B 1 145 ? 69.917  72.163  79.251  1.00 33.77  ? 145 PHE B N   1 
ATOM   3117  C  CA  . PHE B 1 145 ? 69.408  73.525  79.103  1.00 32.26  ? 145 PHE B CA  1 
ATOM   3118  C  C   . PHE B 1 145 ? 67.891  73.618  78.980  1.00 36.54  ? 145 PHE B C   1 
ATOM   3119  O  O   . PHE B 1 145 ? 67.356  74.723  79.083  1.00 34.79  ? 145 PHE B O   1 
ATOM   3120  C  CB  . PHE B 1 145 ? 70.039  74.228  77.885  1.00 30.76  ? 145 PHE B CB  1 
ATOM   3121  C  CG  . PHE B 1 145 ? 69.713  73.576  76.567  1.00 31.42  ? 145 PHE B CG  1 
ATOM   3122  C  CD1 . PHE B 1 145 ? 68.544  73.890  75.886  1.00 30.39  ? 145 PHE B CD1 1 
ATOM   3123  C  CD2 . PHE B 1 145 ? 70.578  72.647  76.009  1.00 31.28  ? 145 PHE B CD2 1 
ATOM   3124  C  CE1 . PHE B 1 145 ? 68.236  73.276  74.683  1.00 35.96  ? 145 PHE B CE1 1 
ATOM   3125  C  CE2 . PHE B 1 145 ? 70.282  72.039  74.800  1.00 31.06  ? 145 PHE B CE2 1 
ATOM   3126  C  CZ  . PHE B 1 145 ? 69.102  72.352  74.138  1.00 34.19  ? 145 PHE B CZ  1 
ATOM   3127  N  N   . ASP B 1 146 ? 67.188  72.513  78.735  1.00 37.14  ? 146 ASP B N   1 
ATOM   3128  C  CA  . ASP B 1 146 ? 65.733  72.556  78.579  1.00 37.81  ? 146 ASP B CA  1 
ATOM   3129  C  C   . ASP B 1 146 ? 65.073  72.195  79.911  1.00 39.97  ? 146 ASP B C   1 
ATOM   3130  O  O   . ASP B 1 146 ? 64.499  71.120  80.096  1.00 40.93  ? 146 ASP B O   1 
ATOM   3131  C  CB  . ASP B 1 146 ? 65.294  71.632  77.441  1.00 39.36  ? 146 ASP B CB  1 
ATOM   3132  C  CG  . ASP B 1 146 ? 63.816  71.780  77.093  1.00 38.50  ? 146 ASP B CG  1 
ATOM   3133  O  OD1 . ASP B 1 146 ? 63.127  72.587  77.736  1.00 40.03  ? 146 ASP B OD1 1 
ATOM   3134  O  OD2 . ASP B 1 146 ? 63.345  71.094  76.158  1.00 47.26  ? 146 ASP B OD2 1 
ATOM   3135  N  N   . ARG B 1 147 ? 65.160  73.143  80.844  1.00 44.14  ? 147 ARG B N   1 
ATOM   3136  C  CA  . ARG B 1 147 ? 64.665  72.993  82.210  1.00 45.35  ? 147 ARG B CA  1 
ATOM   3137  C  C   . ARG B 1 147 ? 63.654  74.090  82.495  1.00 49.20  ? 147 ARG B C   1 
ATOM   3138  O  O   . ARG B 1 147 ? 64.023  75.278  82.477  1.00 51.44  ? 147 ARG B O   1 
ATOM   3139  C  CB  . ARG B 1 147 ? 65.817  73.060  83.213  1.00 43.45  ? 147 ARG B CB  1 
ATOM   3140  C  CG  . ARG B 1 147 ? 66.823  71.938  83.057  1.00 40.96  ? 147 ARG B CG  1 
ATOM   3141  C  CD  . ARG B 1 147 ? 67.873  71.956  84.157  1.00 41.05  ? 147 ARG B CD  1 
ATOM   3142  N  NE  . ARG B 1 147 ? 68.907  70.970  83.886  1.00 43.02  ? 147 ARG B NE  1 
ATOM   3143  C  CZ  . ARG B 1 147 ? 69.556  70.284  84.816  1.00 45.08  ? 147 ARG B CZ  1 
ATOM   3144  N  NH1 . ARG B 1 147 ? 69.337  70.491  86.105  1.00 46.04  ? 147 ARG B NH1 1 
ATOM   3145  N  NH2 . ARG B 1 147 ? 70.456  69.379  84.442  1.00 37.79  ? 147 ARG B NH2 1 
ATOM   3146  N  N   . PRO B 1 148 ? 62.386  73.762  82.769  1.00 53.55  ? 148 PRO B N   1 
ATOM   3147  C  CA  . PRO B 1 148 ? 61.358  74.817  82.879  1.00 53.82  ? 148 PRO B CA  1 
ATOM   3148  C  C   . PRO B 1 148 ? 61.585  75.780  84.032  1.00 51.26  ? 148 PRO B C   1 
ATOM   3149  O  O   . PRO B 1 148 ? 61.033  76.888  84.025  1.00 56.40  ? 148 PRO B O   1 
ATOM   3150  C  CB  . PRO B 1 148 ? 60.057  74.019  83.059  1.00 51.04  ? 148 PRO B CB  1 
ATOM   3151  C  CG  . PRO B 1 148 ? 60.383  72.654  82.503  1.00 48.96  ? 148 PRO B CG  1 
ATOM   3152  C  CD  . PRO B 1 148 ? 61.807  72.419  82.902  1.00 48.63  ? 148 PRO B CD  1 
ATOM   3153  N  N   . ASP B 1 149 ? 62.406  75.404  85.002  1.00 50.41  ? 149 ASP B N   1 
ATOM   3154  C  CA  . ASP B 1 149 ? 62.674  76.213  86.183  1.00 50.11  ? 149 ASP B CA  1 
ATOM   3155  C  C   . ASP B 1 149 ? 63.658  77.356  85.937  1.00 47.74  ? 149 ASP B C   1 
ATOM   3156  O  O   . ASP B 1 149 ? 63.728  78.274  86.760  1.00 47.59  ? 149 ASP B O   1 
ATOM   3157  C  CB  . ASP B 1 149 ? 63.216  75.289  87.276  1.00 52.53  ? 149 ASP B CB  1 
ATOM   3158  C  CG  . ASP B 1 149 ? 64.129  74.192  86.704  1.00 55.40  ? 149 ASP B CG  1 
ATOM   3159  O  OD1 . ASP B 1 149 ? 63.754  73.571  85.679  1.00 54.09  ? 149 ASP B OD1 1 
ATOM   3160  O  OD2 . ASP B 1 149 ? 65.218  73.949  87.265  1.00 55.99  ? 149 ASP B OD2 1 
ATOM   3161  N  N   . VAL B 1 150 ? 64.422  77.328  84.840  1.00 44.19  ? 150 VAL B N   1 
ATOM   3162  C  CA  . VAL B 1 150 ? 65.537  78.257  84.672  1.00 41.66  ? 150 VAL B CA  1 
ATOM   3163  C  C   . VAL B 1 150 ? 65.022  79.643  84.308  1.00 38.81  ? 150 VAL B C   1 
ATOM   3164  O  O   . VAL B 1 150 ? 64.112  79.793  83.486  1.00 36.61  ? 150 VAL B O   1 
ATOM   3165  C  CB  . VAL B 1 150 ? 66.518  77.733  83.614  1.00 41.46  ? 150 VAL B CB  1 
ATOM   3166  C  CG1 . VAL B 1 150 ? 67.487  78.834  83.204  1.00 39.25  ? 150 VAL B CG1 1 
ATOM   3167  C  CG2 . VAL B 1 150 ? 67.276  76.547  84.153  1.00 40.74  ? 150 VAL B CG2 1 
ATOM   3168  N  N   . LYS B 1 151 ? 65.594  80.664  84.938  1.00 37.99  ? 151 LYS B N   1 
ATOM   3169  C  CA  . LYS B 1 151 ? 65.264  82.047  84.633  1.00 39.55  ? 151 LYS B CA  1 
ATOM   3170  C  C   . LYS B 1 151 ? 66.286  82.581  83.627  1.00 38.97  ? 151 LYS B C   1 
ATOM   3171  O  O   . LYS B 1 151 ? 67.483  82.661  83.930  1.00 38.30  ? 151 LYS B O   1 
ATOM   3172  C  CB  . LYS B 1 151 ? 65.247  82.880  85.911  1.00 39.63  ? 151 LYS B CB  1 
ATOM   3173  C  CG  . LYS B 1 151 ? 64.465  84.180  85.783  1.00 49.78  ? 151 LYS B CG  1 
ATOM   3174  C  CD  . LYS B 1 151 ? 64.906  85.224  86.816  1.00 58.39  ? 151 LYS B CD  1 
ATOM   3175  C  CE  . LYS B 1 151 ? 64.767  84.732  88.265  1.00 60.86  ? 151 LYS B CE  1 
ATOM   3176  N  NZ  . LYS B 1 151 ? 63.414  85.022  88.832  1.00 62.21  ? 151 LYS B NZ  1 
ATOM   3177  N  N   . TRP B 1 152 ? 65.819  82.932  82.428  1.00 30.67  ? 152 TRP B N   1 
ATOM   3178  C  CA  . TRP B 1 152 ? 66.688  83.296  81.317  1.00 31.14  ? 152 TRP B CA  1 
ATOM   3179  C  C   . TRP B 1 152 ? 66.588  84.788  81.010  1.00 32.00  ? 152 TRP B C   1 
ATOM   3180  O  O   . TRP B 1 152 ? 65.491  85.356  80.974  1.00 35.63  ? 152 TRP B O   1 
ATOM   3181  C  CB  . TRP B 1 152 ? 66.313  82.523  80.050  1.00 26.82  ? 152 TRP B CB  1 
ATOM   3182  C  CG  . TRP B 1 152 ? 66.572  81.058  80.028  1.00 26.87  ? 152 TRP B CG  1 
ATOM   3183  C  CD1 . TRP B 1 152 ? 65.658  80.071  80.243  1.00 31.14  ? 152 TRP B CD1 1 
ATOM   3184  C  CD2 . TRP B 1 152 ? 67.793  80.396  79.663  1.00 26.51  ? 152 TRP B CD2 1 
ATOM   3185  N  NE1 . TRP B 1 152 ? 66.242  78.839  80.086  1.00 31.91  ? 152 TRP B NE1 1 
ATOM   3186  C  CE2 . TRP B 1 152 ? 67.551  79.010  79.724  1.00 26.50  ? 152 TRP B CE2 1 
ATOM   3187  C  CE3 . TRP B 1 152 ? 69.070  80.841  79.301  1.00 26.74  ? 152 TRP B CE3 1 
ATOM   3188  C  CZ2 . TRP B 1 152 ? 68.537  78.068  79.451  1.00 28.71  ? 152 TRP B CZ2 1 
ATOM   3189  C  CZ3 . TRP B 1 152 ? 70.054  79.898  79.028  1.00 22.22  ? 152 TRP B CZ3 1 
ATOM   3190  C  CH2 . TRP B 1 152 ? 69.780  78.533  79.103  1.00 25.60  ? 152 TRP B CH2 1 
ATOM   3191  N  N   . HIS B 1 153 ? 67.731  85.421  80.771  1.00 26.57  ? 153 HIS B N   1 
ATOM   3192  C  CA  . HIS B 1 153 ? 67.783  86.695  80.068  1.00 25.40  ? 153 HIS B CA  1 
ATOM   3193  C  C   . HIS B 1 153 ? 68.348  86.400  78.677  1.00 28.79  ? 153 HIS B C   1 
ATOM   3194  O  O   . HIS B 1 153 ? 69.521  86.038  78.533  1.00 23.94  ? 153 HIS B O   1 
ATOM   3195  C  CB  . HIS B 1 153 ? 68.634  87.728  80.808  1.00 21.90  ? 153 HIS B CB  1 
ATOM   3196  C  CG  . HIS B 1 153 ? 68.744  89.034  80.085  1.00 22.67  ? 153 HIS B CG  1 
ATOM   3197  N  ND1 . HIS B 1 153 ? 67.766  89.489  79.227  1.00 26.20  ? 153 HIS B ND1 1 
ATOM   3198  C  CD2 . HIS B 1 153 ? 69.716  89.980  80.080  1.00 24.64  ? 153 HIS B CD2 1 
ATOM   3199  C  CE1 . HIS B 1 153 ? 68.132  90.655  78.723  1.00 23.10  ? 153 HIS B CE1 1 
ATOM   3200  N  NE2 . HIS B 1 153 ? 69.311  90.973  79.219  1.00 23.05  ? 153 HIS B NE2 1 
ATOM   3201  N  N   . LEU B 1 154 ? 67.517  86.537  77.658  1.00 28.57  ? 154 LEU B N   1 
ATOM   3202  C  CA  . LEU B 1 154 ? 67.897  86.174  76.298  1.00 26.73  ? 154 LEU B CA  1 
ATOM   3203  C  C   . LEU B 1 154 ? 68.298  87.445  75.556  1.00 24.20  ? 154 LEU B C   1 
ATOM   3204  O  O   . LEU B 1 154 ? 67.449  88.288  75.245  1.00 23.85  ? 154 LEU B O   1 
ATOM   3205  C  CB  . LEU B 1 154 ? 66.754  85.440  75.601  1.00 27.51  ? 154 LEU B CB  1 
ATOM   3206  C  CG  . LEU B 1 154 ? 66.366  84.116  76.257  1.00 30.35  ? 154 LEU B CG  1 
ATOM   3207  C  CD1 . LEU B 1 154 ? 65.289  83.391  75.443  1.00 28.72  ? 154 LEU B CD1 1 
ATOM   3208  C  CD2 . LEU B 1 154 ? 67.605  83.243  76.413  1.00 26.96  ? 154 LEU B CD2 1 
ATOM   3209  N  N   . LEU B 1 155 ? 69.591  87.565  75.259  1.00 24.75  ? 155 LEU B N   1 
ATOM   3210  C  CA  . LEU B 1 155 ? 70.109  88.765  74.622  1.00 24.08  ? 155 LEU B CA  1 
ATOM   3211  C  C   . LEU B 1 155 ? 69.651  88.856  73.167  1.00 25.70  ? 155 LEU B C   1 
ATOM   3212  O  O   . LEU B 1 155 ? 69.518  87.846  72.467  1.00 24.64  ? 155 LEU B O   1 
ATOM   3213  C  CB  . LEU B 1 155 ? 71.635  88.780  74.701  1.00 23.92  ? 155 LEU B CB  1 
ATOM   3214  C  CG  . LEU B 1 155 ? 72.220  88.711  76.120  1.00 23.79  ? 155 LEU B CG  1 
ATOM   3215  C  CD1 . LEU B 1 155 ? 73.768  88.722  76.076  1.00 22.47  ? 155 LEU B CD1 1 
ATOM   3216  C  CD2 . LEU B 1 155 ? 71.690  89.886  76.966  1.00 21.23  ? 155 LEU B CD2 1 
ATOM   3217  N  N   . GLU B 1 156 ? 69.450  90.081  72.700  1.00 20.74  ? 156 GLU B N   1 
ATOM   3218  C  CA  . GLU B 1 156 ? 69.040  90.300  71.321  1.00 28.50  ? 156 GLU B CA  1 
ATOM   3219  C  C   . GLU B 1 156 ? 70.231  90.701  70.451  1.00 30.94  ? 156 GLU B C   1 
ATOM   3220  O  O   . GLU B 1 156 ? 71.369  90.854  70.914  1.00 25.98  ? 156 GLU B O   1 
ATOM   3221  C  CB  . GLU B 1 156 ? 67.947  91.367  71.240  1.00 27.29  ? 156 GLU B CB  1 
ATOM   3222  C  CG  . GLU B 1 156 ? 66.738  91.064  72.070  1.00 28.81  ? 156 GLU B CG  1 
ATOM   3223  C  CD  . GLU B 1 156 ? 65.813  90.047  71.410  1.00 33.37  ? 156 GLU B CD  1 
ATOM   3224  O  OE1 . GLU B 1 156 ? 66.105  89.583  70.279  1.00 35.71  ? 156 GLU B OE1 1 
ATOM   3225  O  OE2 . GLU B 1 156 ? 64.774  89.737  72.011  1.00 28.51  ? 156 GLU B OE2 1 
ATOM   3226  N  N   . GLY B 1 157 ? 69.938  90.892  69.159  1.00 33.74  ? 157 GLY B N   1 
ATOM   3227  C  CA  . GLY B 1 157 ? 70.975  91.240  68.202  1.00 34.24  ? 157 GLY B CA  1 
ATOM   3228  C  C   . GLY B 1 157 ? 71.705  92.530  68.518  1.00 35.59  ? 157 GLY B C   1 
ATOM   3229  O  O   . GLY B 1 157 ? 72.907  92.637  68.267  1.00 45.26  ? 157 GLY B O   1 
ATOM   3230  N  N   . HIS B 1 158 ? 71.009  93.522  69.074  1.00 35.74  ? 158 HIS B N   1 
ATOM   3231  C  CA  . HIS B 1 158 ? 71.641  94.792  69.411  1.00 34.84  ? 158 HIS B CA  1 
ATOM   3232  C  C   . HIS B 1 158 ? 72.297  94.786  70.782  1.00 35.39  ? 158 HIS B C   1 
ATOM   3233  O  O   . HIS B 1 158 ? 72.757  95.838  71.233  1.00 33.25  ? 158 HIS B O   1 
ATOM   3234  C  CB  . HIS B 1 158 ? 70.626  95.940  69.358  1.00 44.74  ? 158 HIS B CB  1 
ATOM   3235  C  CG  . HIS B 1 158 ? 70.097  96.227  67.985  1.00 50.88  ? 158 HIS B CG  1 
ATOM   3236  N  ND1 . HIS B 1 158 ? 70.866  96.772  66.979  1.00 54.09  ? 158 HIS B ND1 1 
ATOM   3237  C  CD2 . HIS B 1 158 ? 68.869  96.025  67.447  1.00 57.66  ? 158 HIS B CD2 1 
ATOM   3238  C  CE1 . HIS B 1 158 ? 70.134  96.900  65.885  1.00 52.23  ? 158 HIS B CE1 1 
ATOM   3239  N  NE2 . HIS B 1 158 ? 68.920  96.451  66.140  1.00 54.85  ? 158 HIS B NE2 1 
ATOM   3240  N  N   . ASP B 1 159 ? 72.350  93.644  71.466  1.00 32.61  ? 159 ASP B N   1 
ATOM   3241  C  CA  . ASP B 1 159 ? 72.886  93.630  72.819  1.00 27.60  ? 159 ASP B CA  1 
ATOM   3242  C  C   . ASP B 1 159 ? 74.384  93.330  72.871  1.00 27.19  ? 159 ASP B C   1 
ATOM   3243  O  O   . ASP B 1 159 ? 74.905  93.044  73.952  1.00 23.05  ? 159 ASP B O   1 
ATOM   3244  C  CB  . ASP B 1 159 ? 72.125  92.616  73.681  1.00 26.81  ? 159 ASP B CB  1 
ATOM   3245  C  CG  . ASP B 1 159 ? 70.711  93.074  74.022  1.00 29.13  ? 159 ASP B CG  1 
ATOM   3246  O  OD1 . ASP B 1 159 ? 70.519  94.264  74.353  1.00 33.41  ? 159 ASP B OD1 1 
ATOM   3247  O  OD2 . ASP B 1 159 ? 69.789  92.239  73.962  1.00 28.00  ? 159 ASP B OD2 1 
ATOM   3248  N  N   . ASP B 1 160 ? 75.082  93.374  71.738  1.00 25.81  ? 160 ASP B N   1 
ATOM   3249  C  CA  . ASP B 1 160 ? 76.512  93.094  71.743  1.00 24.08  ? 160 ASP B CA  1 
ATOM   3250  C  C   . ASP B 1 160 ? 77.222  94.049  72.696  1.00 25.39  ? 160 ASP B C   1 
ATOM   3251  O  O   . ASP B 1 160 ? 76.892  95.232  72.772  1.00 25.33  ? 160 ASP B O   1 
ATOM   3252  C  CB  . ASP B 1 160 ? 77.077  93.215  70.328  1.00 23.03  ? 160 ASP B CB  1 
ATOM   3253  C  CG  . ASP B 1 160 ? 78.475  92.590  70.183  1.00 27.56  ? 160 ASP B CG  1 
ATOM   3254  O  OD1 . ASP B 1 160 ? 79.035  92.034  71.148  1.00 23.16  ? 160 ASP B OD1 1 
ATOM   3255  O  OD2 . ASP B 1 160 ? 79.022  92.653  69.069  1.00 29.45  ? 160 ASP B OD2 1 
ATOM   3256  N  N   . GLY B 1 161 ? 78.183  93.528  73.450  1.00 21.29  ? 161 GLY B N   1 
ATOM   3257  C  CA  . GLY B 1 161 ? 78.810  94.333  74.469  1.00 22.69  ? 161 GLY B CA  1 
ATOM   3258  C  C   . GLY B 1 161 ? 78.090  94.343  75.800  1.00 25.36  ? 161 GLY B C   1 
ATOM   3259  O  O   . GLY B 1 161 ? 78.512  95.082  76.706  1.00 24.58  ? 161 GLY B O   1 
ATOM   3260  N  N   . TYR B 1 162 ? 77.053  93.514  75.958  1.00 21.39  ? 162 TYR B N   1 
ATOM   3261  C  CA  . TYR B 1 162 ? 76.248  93.483  77.177  1.00 22.70  ? 162 TYR B CA  1 
ATOM   3262  C  C   . TYR B 1 162 ? 77.113  93.393  78.438  1.00 23.19  ? 162 TYR B C   1 
ATOM   3263  O  O   . TYR B 1 162 ? 77.951  92.500  78.571  1.00 23.32  ? 162 TYR B O   1 
ATOM   3264  C  CB  . TYR B 1 162 ? 75.252  92.308  77.131  1.00 19.93  ? 162 TYR B CB  1 
ATOM   3265  C  CG  . TYR B 1 162 ? 74.278  92.376  78.288  1.00 26.08  ? 162 TYR B CG  1 
ATOM   3266  C  CD1 . TYR B 1 162 ? 73.161  93.219  78.240  1.00 21.17  ? 162 TYR B CD1 1 
ATOM   3267  C  CD2 . TYR B 1 162 ? 74.511  91.656  79.464  1.00 23.08  ? 162 TYR B CD2 1 
ATOM   3268  C  CE1 . TYR B 1 162 ? 72.278  93.312  79.335  1.00 26.87  ? 162 TYR B CE1 1 
ATOM   3269  C  CE2 . TYR B 1 162 ? 73.635  91.741  80.548  1.00 24.16  ? 162 TYR B CE2 1 
ATOM   3270  C  CZ  . TYR B 1 162 ? 72.530  92.577  80.480  1.00 25.80  ? 162 TYR B CZ  1 
ATOM   3271  O  OH  . TYR B 1 162 ? 71.683  92.656  81.556  1.00 28.37  ? 162 TYR B OH  1 
ATOM   3272  N  N   . ASP B 1 163 ? 76.873  94.322  79.375  1.00 29.63  ? 163 ASP B N   1 
ATOM   3273  C  CA  . ASP B 1 163 ? 77.679  94.498  80.584  1.00 25.92  ? 163 ASP B CA  1 
ATOM   3274  C  C   . ASP B 1 163 ? 76.908  93.944  81.788  1.00 26.89  ? 163 ASP B C   1 
ATOM   3275  O  O   . ASP B 1 163 ? 75.926  94.546  82.231  1.00 27.87  ? 163 ASP B O   1 
ATOM   3276  C  CB  . ASP B 1 163 ? 78.008  95.982  80.765  1.00 26.90  ? 163 ASP B CB  1 
ATOM   3277  C  CG  . ASP B 1 163 ? 78.964  96.246  81.936  1.00 29.79  ? 163 ASP B CG  1 
ATOM   3278  O  OD1 . ASP B 1 163 ? 79.010  95.437  82.899  1.00 29.02  ? 163 ASP B OD1 1 
ATOM   3279  O  OD2 . ASP B 1 163 ? 79.683  97.259  81.879  1.00 31.22  ? 163 ASP B OD2 1 
ATOM   3280  N  N   . VAL B 1 164 ? 77.386  92.830  82.345  1.00 24.92  ? 164 VAL B N   1 
ATOM   3281  C  CA  . VAL B 1 164 ? 76.593  92.067  83.312  1.00 25.55  ? 164 VAL B CA  1 
ATOM   3282  C  C   . VAL B 1 164 ? 76.295  92.892  84.572  1.00 28.30  ? 164 VAL B C   1 
ATOM   3283  O  O   . VAL B 1 164 ? 75.144  92.999  85.006  1.00 24.81  ? 164 VAL B O   1 
ATOM   3284  C  CB  . VAL B 1 164 ? 77.306  90.751  83.656  1.00 27.98  ? 164 VAL B CB  1 
ATOM   3285  C  CG1 . VAL B 1 164 ? 76.591  90.067  84.791  1.00 28.80  ? 164 VAL B CG1 1 
ATOM   3286  C  CG2 . VAL B 1 164 ? 77.375  89.838  82.435  1.00 25.35  ? 164 VAL B CG2 1 
ATOM   3287  N  N   . PHE B 1 165 ? 77.324  93.475  85.190  1.00 29.49  ? 165 PHE B N   1 
ATOM   3288  C  CA  . PHE B 1 165 ? 77.114  94.299  86.381  1.00 30.74  ? 165 PHE B CA  1 
ATOM   3289  C  C   . PHE B 1 165 ? 77.020  95.784  86.077  1.00 31.40  ? 165 PHE B C   1 
ATOM   3290  O  O   . PHE B 1 165 ? 76.736  96.564  86.991  1.00 37.09  ? 165 PHE B O   1 
ATOM   3291  C  CB  . PHE B 1 165 ? 78.241  94.082  87.407  1.00 29.70  ? 165 PHE B CB  1 
ATOM   3292  C  CG  . PHE B 1 165 ? 78.330  92.674  87.926  1.00 29.04  ? 165 PHE B CG  1 
ATOM   3293  C  CD1 . PHE B 1 165 ? 77.418  92.204  88.854  1.00 31.77  ? 165 PHE B CD1 1 
ATOM   3294  C  CD2 . PHE B 1 165 ? 79.326  91.822  87.480  1.00 29.09  ? 165 PHE B CD2 1 
ATOM   3295  C  CE1 . PHE B 1 165 ? 77.504  90.908  89.338  1.00 32.09  ? 165 PHE B CE1 1 
ATOM   3296  C  CE2 . PHE B 1 165 ? 79.416  90.524  87.955  1.00 33.26  ? 165 PHE B CE2 1 
ATOM   3297  C  CZ  . PHE B 1 165 ? 78.502  90.069  88.884  1.00 29.79  ? 165 PHE B CZ  1 
ATOM   3298  N  N   . GLY B 1 166 ? 77.253  96.195  84.830  1.00 32.72  ? 166 GLY B N   1 
ATOM   3299  C  CA  . GLY B 1 166 ? 77.201  97.602  84.494  1.00 29.60  ? 166 GLY B CA  1 
ATOM   3300  C  C   . GLY B 1 166 ? 78.423  98.386  84.907  1.00 36.00  ? 166 GLY B C   1 
ATOM   3301  O  O   . GLY B 1 166 ? 78.358  99.621  84.980  1.00 35.10  ? 166 GLY B O   1 
ATOM   3302  N  N   . ASP B 1 167 ? 79.549  97.706  85.157  1.00 30.44  ? 167 ASP B N   1 
ATOM   3303  C  CA  . ASP B 1 167 ? 80.775  98.343  85.628  1.00 32.65  ? 167 ASP B CA  1 
ATOM   3304  C  C   . ASP B 1 167 ? 82.006  97.961  84.811  1.00 32.07  ? 167 ASP B C   1 
ATOM   3305  O  O   . ASP B 1 167 ? 83.132  98.146  85.297  1.00 29.74  ? 167 ASP B O   1 
ATOM   3306  C  CB  . ASP B 1 167 ? 81.037  97.979  87.096  1.00 30.72  ? 167 ASP B CB  1 
ATOM   3307  C  CG  . ASP B 1 167 ? 81.345  96.492  87.284  1.00 31.92  ? 167 ASP B CG  1 
ATOM   3308  O  OD1 . ASP B 1 167 ? 81.253  95.718  86.306  1.00 31.89  ? 167 ASP B OD1 1 
ATOM   3309  O  OD2 . ASP B 1 167 ? 81.689  96.086  88.412  1.00 34.01  ? 167 ASP B OD2 1 
ATOM   3310  N  N   . ASP B 1 168 ? 81.828  97.370  83.630  1.00 28.09  ? 168 ASP B N   1 
ATOM   3311  C  CA  . ASP B 1 168 ? 82.899  97.015  82.697  1.00 29.21  ? 168 ASP B CA  1 
ATOM   3312  C  C   . ASP B 1 168 ? 83.669  95.764  83.113  1.00 29.55  ? 168 ASP B C   1 
ATOM   3313  O  O   . ASP B 1 168 ? 84.662  95.463  82.499  1.00 35.13  ? 168 ASP B O   1 
ATOM   3314  C  CB  . ASP B 1 168 ? 83.857  98.198  82.526  1.00 34.80  ? 168 ASP B CB  1 
ATOM   3315  C  CG  . ASP B 1 168 ? 84.225  98.465  81.088  1.00 43.55  ? 168 ASP B CG  1 
ATOM   3316  O  OD1 . ASP B 1 168 ? 83.399  98.195  80.192  1.00 43.10  ? 168 ASP B OD1 1 
ATOM   3317  O  OD2 . ASP B 1 168 ? 85.342  98.984  80.858  1.00 49.42  ? 168 ASP B OD2 1 
ATOM   3318  N  N   . THR B 1 169 ? 83.222  95.015  84.126  1.00 28.31  ? 169 THR B N   1 
ATOM   3319  C  CA  . THR B 1 169 ? 83.977  93.847  84.577  1.00 28.59  ? 169 THR B CA  1 
ATOM   3320  C  C   . THR B 1 169 ? 83.817  92.672  83.619  1.00 28.09  ? 169 THR B C   1 
ATOM   3321  O  O   . THR B 1 169 ? 84.801  92.011  83.272  1.00 27.97  ? 169 THR B O   1 
ATOM   3322  C  CB  . THR B 1 169 ? 83.533  93.433  85.992  1.00 27.59  ? 169 THR B CB  1 
ATOM   3323  O  OG1 . THR B 1 169 ? 83.791  94.498  86.908  1.00 35.19  ? 169 THR B OG1 1 
ATOM   3324  C  CG2 . THR B 1 169 ? 84.303  92.217  86.466  1.00 32.27  ? 169 THR B CG2 1 
ATOM   3325  N  N   . ILE B 1 170 ? 82.583  92.371  83.207  1.00 25.00  ? 170 ILE B N   1 
ATOM   3326  C  CA  . ILE B 1 170 ? 82.290  91.266  82.301  1.00 25.22  ? 170 ILE B CA  1 
ATOM   3327  C  C   . ILE B 1 170 ? 81.400  91.781  81.171  1.00 26.87  ? 170 ILE B C   1 
ATOM   3328  O  O   . ILE B 1 170 ? 80.290  92.279  81.422  1.00 25.48  ? 170 ILE B O   1 
ATOM   3329  C  CB  . ILE B 1 170 ? 81.609  90.085  83.022  1.00 27.57  ? 170 ILE B CB  1 
ATOM   3330  C  CG1 . ILE B 1 170 ? 82.352  89.720  84.304  1.00 30.61  ? 170 ILE B CG1 1 
ATOM   3331  C  CG2 . ILE B 1 170 ? 81.514  88.875  82.117  1.00 23.55  ? 170 ILE B CG2 1 
ATOM   3332  C  CD1 . ILE B 1 170 ? 81.578  88.755  85.197  1.00 28.10  ? 170 ILE B CD1 1 
ATOM   3333  N  N   . ARG B 1 171 ? 81.869  91.645  79.932  1.00 20.28  ? 171 ARG B N   1 
ATOM   3334  C  CA  . ARG B 1 171 ? 81.099  92.049  78.755  1.00 26.98  ? 171 ARG B CA  1 
ATOM   3335  C  C   . ARG B 1 171 ? 80.977  90.902  77.762  1.00 25.70  ? 171 ARG B C   1 
ATOM   3336  O  O   . ARG B 1 171 ? 81.968  90.231  77.466  1.00 21.67  ? 171 ARG B O   1 
ATOM   3337  C  CB  . ARG B 1 171 ? 81.742  93.236  78.037  1.00 24.69  ? 171 ARG B CB  1 
ATOM   3338  C  CG  . ARG B 1 171 ? 81.539  94.577  78.701  1.00 26.70  ? 171 ARG B CG  1 
ATOM   3339  C  CD  . ARG B 1 171 ? 81.770  95.668  77.668  1.00 30.65  ? 171 ARG B CD  1 
ATOM   3340  N  NE  . ARG B 1 171 ? 81.812  96.976  78.300  1.00 41.12  ? 171 ARG B NE  1 
ATOM   3341  C  CZ  . ARG B 1 171 ? 80.860  97.893  78.180  1.00 44.96  ? 171 ARG B CZ  1 
ATOM   3342  N  NH1 . ARG B 1 171 ? 79.782  97.676  77.435  1.00 36.11  ? 171 ARG B NH1 1 
ATOM   3343  N  NH2 . ARG B 1 171 ? 80.986  99.050  78.835  1.00 39.07  ? 171 ARG B NH2 1 
ATOM   3344  N  N   . PHE B 1 172 ? 79.759  90.701  77.232  1.00 24.74  ? 172 PHE B N   1 
ATOM   3345  C  CA  . PHE B 1 172 ? 79.543  89.758  76.133  1.00 24.44  ? 172 PHE B CA  1 
ATOM   3346  C  C   . PHE B 1 172 ? 80.135  90.314  74.839  1.00 22.56  ? 172 PHE B C   1 
ATOM   3347  O  O   . PHE B 1 172 ? 79.848  91.453  74.469  1.00 22.96  ? 172 PHE B O   1 
ATOM   3348  C  CB  . PHE B 1 172 ? 78.048  89.509  75.910  1.00 21.15  ? 172 PHE B CB  1 
ATOM   3349  C  CG  . PHE B 1 172 ? 77.426  88.500  76.826  1.00 20.31  ? 172 PHE B CG  1 
ATOM   3350  C  CD1 . PHE B 1 172 ? 77.121  88.827  78.147  1.00 20.25  ? 172 PHE B CD1 1 
ATOM   3351  C  CD2 . PHE B 1 172 ? 77.080  87.239  76.347  1.00 20.89  ? 172 PHE B CD2 1 
ATOM   3352  C  CE1 . PHE B 1 172 ? 76.504  87.910  78.988  1.00 20.18  ? 172 PHE B CE1 1 
ATOM   3353  C  CE2 . PHE B 1 172 ? 76.457  86.305  77.187  1.00 21.96  ? 172 PHE B CE2 1 
ATOM   3354  C  CZ  . PHE B 1 172 ? 76.169  86.650  78.520  1.00 19.28  ? 172 PHE B CZ  1 
ATOM   3355  N  N   . ILE B 1 173 ? 80.948  89.512  74.142  1.00 23.66  ? 173 ILE B N   1 
ATOM   3356  C  CA  . ILE B 1 173 ? 81.518  89.895  72.848  1.00 19.83  ? 173 ILE B CA  1 
ATOM   3357  C  C   . ILE B 1 173 ? 81.006  88.894  71.811  1.00 22.43  ? 173 ILE B C   1 
ATOM   3358  O  O   . ILE B 1 173 ? 81.512  87.765  71.721  1.00 19.55  ? 173 ILE B O   1 
ATOM   3359  C  CB  . ILE B 1 173 ? 83.051  89.944  72.863  1.00 21.89  ? 173 ILE B CB  1 
ATOM   3360  C  CG1 . ILE B 1 173 ? 83.562  90.784  74.049  1.00 21.19  ? 173 ILE B CG1 1 
ATOM   3361  C  CG2 . ILE B 1 173 ? 83.566  90.477  71.522  1.00 14.99  ? 173 ILE B CG2 1 
ATOM   3362  C  CD1 . ILE B 1 173 ? 83.544  92.310  73.819  1.00 20.11  ? 173 ILE B CD1 1 
ATOM   3363  N  N   . PHE B 1 174 ? 80.004  89.306  71.019  1.00 20.00  ? 174 PHE B N   1 
ATOM   3364  C  CA  . PHE B 1 174 ? 79.315  88.380  70.116  1.00 20.16  ? 174 PHE B CA  1 
ATOM   3365  C  C   . PHE B 1 174 ? 80.298  87.863  69.078  1.00 19.60  ? 174 PHE B C   1 
ATOM   3366  O  O   . PHE B 1 174 ? 81.012  88.649  68.442  1.00 21.56  ? 174 PHE B O   1 
ATOM   3367  C  CB  . PHE B 1 174 ? 78.112  89.072  69.432  1.00 19.62  ? 174 PHE B CB  1 
ATOM   3368  C  CG  . PHE B 1 174 ? 76.900  89.319  70.363  1.00 21.92  ? 174 PHE B CG  1 
ATOM   3369  C  CD1 . PHE B 1 174 ? 76.933  88.937  71.702  1.00 19.23  ? 174 PHE B CD1 1 
ATOM   3370  C  CD2 . PHE B 1 174 ? 75.743  89.950  69.875  1.00 20.43  ? 174 PHE B CD2 1 
ATOM   3371  C  CE1 . PHE B 1 174 ? 75.839  89.163  72.542  1.00 22.01  ? 174 PHE B CE1 1 
ATOM   3372  C  CE2 . PHE B 1 174 ? 74.635  90.187  70.709  1.00 22.54  ? 174 PHE B CE2 1 
ATOM   3373  C  CZ  . PHE B 1 174 ? 74.681  89.799  72.038  1.00 20.15  ? 174 PHE B CZ  1 
ATOM   3374  N  N   . THR B 1 175 ? 80.383  86.539  68.937  1.00 17.61  ? 175 THR B N   1 
ATOM   3375  C  CA  . THR B 1 175 ? 81.315  85.928  67.987  1.00 18.22  ? 175 THR B CA  1 
ATOM   3376  C  C   . THR B 1 175 ? 80.620  84.779  67.263  1.00 21.12  ? 175 THR B C   1 
ATOM   3377  O  O   . THR B 1 175 ? 80.929  83.602  67.477  1.00 22.40  ? 175 THR B O   1 
ATOM   3378  C  CB  . THR B 1 175 ? 82.605  85.477  68.687  1.00 20.31  ? 175 THR B CB  1 
ATOM   3379  O  OG1 . THR B 1 175 ? 82.329  84.743  69.886  1.00 16.92  ? 175 THR B OG1 1 
ATOM   3380  C  CG2 . THR B 1 175 ? 83.463  86.681  69.045  1.00 18.80  ? 175 THR B CG2 1 
ATOM   3381  N  N   . PRO B 1 176 ? 79.669  85.093  66.383  1.00 17.98  ? 176 PRO B N   1 
ATOM   3382  C  CA  . PRO B 1 176 ? 78.931  84.030  65.699  1.00 19.38  ? 176 PRO B CA  1 
ATOM   3383  C  C   . PRO B 1 176 ? 79.858  83.216  64.823  1.00 22.01  ? 176 PRO B C   1 
ATOM   3384  O  O   . PRO B 1 176 ? 80.864  83.721  64.302  1.00 24.41  ? 176 PRO B O   1 
ATOM   3385  C  CB  . PRO B 1 176 ? 77.905  84.787  64.843  1.00 18.97  ? 176 PRO B CB  1 
ATOM   3386  C  CG  . PRO B 1 176 ? 78.528  86.142  64.623  1.00 20.20  ? 176 PRO B CG  1 
ATOM   3387  C  CD  . PRO B 1 176 ? 79.245  86.431  65.940  1.00 20.74  ? 176 PRO B CD  1 
ATOM   3388  N  N   . GLY B 1 177 ? 79.497  81.949  64.650  1.00 18.78  ? 177 GLY B N   1 
ATOM   3389  C  CA  . GLY B 1 177 ? 80.141  81.136  63.640  1.00 23.08  ? 177 GLY B CA  1 
ATOM   3390  C  C   . GLY B 1 177 ? 80.298  79.705  64.088  1.00 23.64  ? 177 GLY B C   1 
ATOM   3391  O  O   . GLY B 1 177 ? 79.779  78.777  63.455  1.00 26.89  ? 177 GLY B O   1 
ATOM   3392  N  N   . HIS B 1 178 ? 81.033  79.512  65.178  1.00 24.63  ? 178 HIS B N   1 
ATOM   3393  C  CA  . HIS B 1 178 ? 81.163  78.165  65.712  1.00 26.16  ? 178 HIS B CA  1 
ATOM   3394  C  C   . HIS B 1 178 ? 79.797  77.618  66.083  1.00 23.52  ? 178 HIS B C   1 
ATOM   3395  O  O   . HIS B 1 178 ? 79.504  76.444  65.848  1.00 23.01  ? 178 HIS B O   1 
ATOM   3396  C  CB  . HIS B 1 178 ? 82.090  78.162  66.918  1.00 25.68  ? 178 HIS B CB  1 
ATOM   3397  C  CG  . HIS B 1 178 ? 81.983  76.925  67.745  1.00 25.92  ? 178 HIS B CG  1 
ATOM   3398  N  ND1 . HIS B 1 178 ? 82.540  75.726  67.361  1.00 28.83  ? 178 HIS B ND1 1 
ATOM   3399  C  CD2 . HIS B 1 178 ? 81.367  76.695  68.925  1.00 26.77  ? 178 HIS B CD2 1 
ATOM   3400  C  CE1 . HIS B 1 178 ? 82.287  74.816  68.281  1.00 26.01  ? 178 HIS B CE1 1 
ATOM   3401  N  NE2 . HIS B 1 178 ? 81.577  75.378  69.239  1.00 28.59  ? 178 HIS B NE2 1 
ATOM   3402  N  N   . ALA B 1 179 ? 78.950  78.472  66.636  1.00 21.38  ? 179 ALA B N   1 
ATOM   3403  C  CA  . ALA B 1 179 ? 77.528  78.255  66.841  1.00 23.70  ? 179 ALA B CA  1 
ATOM   3404  C  C   . ALA B 1 179 ? 76.795  79.539  66.482  1.00 22.63  ? 179 ALA B C   1 
ATOM   3405  O  O   . ALA B 1 179 ? 77.380  80.632  66.559  1.00 21.87  ? 179 ALA B O   1 
ATOM   3406  C  CB  . ALA B 1 179 ? 77.222  77.860  68.296  1.00 22.83  ? 179 ALA B CB  1 
ATOM   3407  N  N   . PRO B 1 180 ? 75.520  79.449  66.081  1.00 19.31  ? 180 PRO B N   1 
ATOM   3408  C  CA  . PRO B 1 180 ? 74.806  80.660  65.642  1.00 19.79  ? 180 PRO B CA  1 
ATOM   3409  C  C   . PRO B 1 180 ? 74.818  81.792  66.669  1.00 20.25  ? 180 PRO B C   1 
ATOM   3410  O  O   . PRO B 1 180 ? 74.993  82.963  66.295  1.00 19.77  ? 180 PRO B O   1 
ATOM   3411  C  CB  . PRO B 1 180 ? 73.381  80.147  65.370  1.00 23.29  ? 180 PRO B CB  1 
ATOM   3412  C  CG  . PRO B 1 180 ? 73.528  78.670  65.140  1.00 23.82  ? 180 PRO B CG  1 
ATOM   3413  C  CD  . PRO B 1 180 ? 74.659  78.253  66.051  1.00 21.60  ? 180 PRO B CD  1 
ATOM   3414  N  N   . GLY B 1 181 ? 74.668  81.478  67.951  1.00 19.98  ? 181 GLY B N   1 
ATOM   3415  C  CA  . GLY B 1 181 ? 74.677  82.511  68.970  1.00 21.18  ? 181 GLY B CA  1 
ATOM   3416  C  C   . GLY B 1 181 ? 75.877  82.487  69.901  1.00 24.95  ? 181 GLY B C   1 
ATOM   3417  O  O   . GLY B 1 181 ? 75.764  82.862  71.081  1.00 20.37  ? 181 GLY B O   1 
ATOM   3418  N  N   . HIS B 1 182 ? 77.030  82.049  69.392  1.00 21.13  ? 182 HIS B N   1 
ATOM   3419  C  CA  . HIS B 1 182 ? 78.226  81.969  70.223  1.00 20.56  ? 182 HIS B CA  1 
ATOM   3420  C  C   . HIS B 1 182 ? 78.700  83.359  70.615  1.00 22.64  ? 182 HIS B C   1 
ATOM   3421  O  O   . HIS B 1 182 ? 78.747  84.275  69.785  1.00 22.28  ? 182 HIS B O   1 
ATOM   3422  C  CB  . HIS B 1 182 ? 79.370  81.249  69.510  1.00 21.45  ? 182 HIS B CB  1 
ATOM   3423  C  CG  . HIS B 1 182 ? 80.603  81.125  70.354  1.00 27.27  ? 182 HIS B CG  1 
ATOM   3424  N  ND1 . HIS B 1 182 ? 81.578  82.104  70.404  1.00 23.70  ? 182 HIS B ND1 1 
ATOM   3425  C  CD2 . HIS B 1 182 ? 81.009  80.145  71.200  1.00 24.07  ? 182 HIS B CD2 1 
ATOM   3426  C  CE1 . HIS B 1 182 ? 82.526  81.729  71.243  1.00 24.44  ? 182 HIS B CE1 1 
ATOM   3427  N  NE2 . HIS B 1 182 ? 82.204  80.548  71.742  1.00 23.91  ? 182 HIS B NE2 1 
ATOM   3428  N  N   . SER B 1 183 ? 79.103  83.501  71.877  1.00 20.82  ? 183 SER B N   1 
ATOM   3429  C  CA  . SER B 1 183 ? 79.701  84.740  72.338  1.00 19.55  ? 183 SER B CA  1 
ATOM   3430  C  C   . SER B 1 183 ? 80.975  84.463  73.128  1.00 23.50  ? 183 SER B C   1 
ATOM   3431  O  O   . SER B 1 183 ? 81.071  83.471  73.855  1.00 23.13  ? 183 SER B O   1 
ATOM   3432  C  CB  . SER B 1 183 ? 78.707  85.541  73.174  1.00 20.33  ? 183 SER B CB  1 
ATOM   3433  O  OG  . SER B 1 183 ? 79.296  86.769  73.558  1.00 28.09  ? 183 SER B OG  1 
ATOM   3434  N  N   . SER B 1 184 ? 81.959  85.341  72.958  1.00 20.96  ? 184 SER B N   1 
ATOM   3435  C  CA  . SER B 1 184 ? 83.150  85.375  73.783  1.00 23.28  ? 184 SER B CA  1 
ATOM   3436  C  C   . SER B 1 184 ? 82.922  86.357  74.931  1.00 24.13  ? 184 SER B C   1 
ATOM   3437  O  O   . SER B 1 184 ? 81.845  86.944  75.060  1.00 21.46  ? 184 SER B O   1 
ATOM   3438  C  CB  . SER B 1 184 ? 84.362  85.759  72.936  1.00 21.73  ? 184 SER B CB  1 
ATOM   3439  O  OG  . SER B 1 184 ? 84.515  84.844  71.849  1.00 22.92  ? 184 SER B OG  1 
ATOM   3440  N  N   . PHE B 1 185 ? 83.943  86.559  75.772  1.00 21.85  ? 185 PHE B N   1 
ATOM   3441  C  CA  . PHE B 1 185 ? 83.824  87.504  76.878  1.00 22.37  ? 185 PHE B CA  1 
ATOM   3442  C  C   . PHE B 1 185 ? 85.114  88.279  77.069  1.00 24.11  ? 185 PHE B C   1 
ATOM   3443  O  O   . PHE B 1 185 ? 86.204  87.698  77.074  1.00 25.52  ? 185 PHE B O   1 
ATOM   3444  C  CB  . PHE B 1 185 ? 83.463  86.803  78.191  1.00 22.11  ? 185 PHE B CB  1 
ATOM   3445  C  CG  . PHE B 1 185 ? 82.170  86.057  78.132  1.00 23.46  ? 185 PHE B CG  1 
ATOM   3446  C  CD1 . PHE B 1 185 ? 80.970  86.692  78.445  1.00 23.26  ? 185 PHE B CD1 1 
ATOM   3447  C  CD2 . PHE B 1 185 ? 82.146  84.726  77.723  1.00 22.15  ? 185 PHE B CD2 1 
ATOM   3448  C  CE1 . PHE B 1 185 ? 79.756  86.001  78.387  1.00 22.79  ? 185 PHE B CE1 1 
ATOM   3449  C  CE2 . PHE B 1 185 ? 80.949  84.029  77.650  1.00 23.99  ? 185 PHE B CE2 1 
ATOM   3450  C  CZ  . PHE B 1 185 ? 79.745  84.665  77.983  1.00 25.99  ? 185 PHE B CZ  1 
ATOM   3451  N  N   . LEU B 1 186 ? 84.975  89.592  77.219  1.00 22.09  ? 186 LEU B N   1 
ATOM   3452  C  CA  . LEU B 1 186 ? 86.062  90.468  77.617  1.00 22.38  ? 186 LEU B CA  1 
ATOM   3453  C  C   . LEU B 1 186 ? 85.865  90.819  79.082  1.00 27.52  ? 186 LEU B C   1 
ATOM   3454  O  O   . LEU B 1 186 ? 84.829  91.378  79.455  1.00 28.00  ? 186 LEU B O   1 
ATOM   3455  C  CB  . LEU B 1 186 ? 86.096  91.738  76.770  1.00 21.43  ? 186 LEU B CB  1 
ATOM   3456  C  CG  . LEU B 1 186 ? 87.129  92.737  77.265  1.00 23.93  ? 186 LEU B CG  1 
ATOM   3457  C  CD1 . LEU B 1 186 ? 88.524  92.217  76.964  1.00 25.97  ? 186 LEU B CD1 1 
ATOM   3458  C  CD2 . LEU B 1 186 ? 86.910  94.123  76.687  1.00 26.63  ? 186 LEU B CD2 1 
ATOM   3459  N  N   . LEU B 1 187 ? 86.852  90.490  79.903  1.00 27.21  ? 187 LEU B N   1 
ATOM   3460  C  CA  . LEU B 1 187 ? 86.832  90.783  81.326  1.00 26.35  ? 187 LEU B CA  1 
ATOM   3461  C  C   . LEU B 1 187 ? 87.778  91.938  81.619  1.00 25.58  ? 187 LEU B C   1 
ATOM   3462  O  O   . LEU B 1 187 ? 88.824  92.084  80.976  1.00 29.61  ? 187 LEU B O   1 
ATOM   3463  C  CB  . LEU B 1 187 ? 87.258  89.557  82.144  1.00 28.81  ? 187 LEU B CB  1 
ATOM   3464  C  CG  . LEU B 1 187 ? 86.266  88.471  82.526  1.00 26.99  ? 187 LEU B CG  1 
ATOM   3465  C  CD1 . LEU B 1 187 ? 85.381  88.071  81.372  1.00 27.93  ? 187 LEU B CD1 1 
ATOM   3466  C  CD2 . LEU B 1 187 ? 87.025  87.249  83.016  1.00 28.30  ? 187 LEU B CD2 1 
ATOM   3467  N  N   . ARG B 1 188 ? 87.426  92.759  82.595  1.00 26.22  ? 188 ARG B N   1 
ATOM   3468  C  CA  . ARG B 1 188 ? 88.367  93.752  83.104  1.00 33.55  ? 188 ARG B CA  1 
ATOM   3469  C  C   . ARG B 1 188 ? 88.554  93.555  84.598  1.00 32.26  ? 188 ARG B C   1 
ATOM   3470  O  O   . ARG B 1 188 ? 87.604  93.718  85.373  1.00 33.63  ? 188 ARG B O   1 
ATOM   3471  C  CB  . ARG B 1 188 ? 87.904  95.172  82.793  1.00 31.37  ? 188 ARG B CB  1 
ATOM   3472  C  CG  . ARG B 1 188 ? 88.214  95.550  81.372  1.00 26.49  ? 188 ARG B CG  1 
ATOM   3473  C  CD  . ARG B 1 188 ? 87.975  96.999  81.126  1.00 34.22  ? 188 ARG B CD  1 
ATOM   3474  N  NE  . ARG B 1 188 ? 87.881  97.257  79.700  1.00 37.88  ? 188 ARG B NE  1 
ATOM   3475  C  CZ  . ARG B 1 188 ? 88.921  97.531  78.927  1.00 35.44  ? 188 ARG B CZ  1 
ATOM   3476  N  NH1 . ARG B 1 188 ? 90.155  97.552  79.409  1.00 33.40  ? 188 ARG B NH1 1 
ATOM   3477  N  NH2 . ARG B 1 188 ? 88.719  97.791  77.638  1.00 33.59  ? 188 ARG B NH2 1 
ATOM   3478  N  N   . LEU B 1 189 ? 89.782  93.207  84.995  1.00 30.73  ? 189 LEU B N   1 
ATOM   3479  C  CA  . LEU B 1 189 ? 90.146  92.950  86.386  1.00 32.82  ? 189 LEU B CA  1 
ATOM   3480  C  C   . LEU B 1 189 ? 91.137  94.002  86.873  1.00 35.35  ? 189 LEU B C   1 
ATOM   3481  O  O   . LEU B 1 189 ? 92.020  94.412  86.112  1.00 34.71  ? 189 LEU B O   1 
ATOM   3482  C  CB  . LEU B 1 189 ? 90.760  91.553  86.534  1.00 30.99  ? 189 LEU B CB  1 
ATOM   3483  C  CG  . LEU B 1 189 ? 89.813  90.447  86.068  1.00 30.56  ? 189 LEU B CG  1 
ATOM   3484  C  CD1 . LEU B 1 189 ? 90.536  89.137  86.021  1.00 31.29  ? 189 LEU B CD1 1 
ATOM   3485  C  CD2 . LEU B 1 189 ? 88.588  90.359  86.992  1.00 28.51  ? 189 LEU B CD2 1 
ATOM   3486  N  N   . PRO B 1 190 ? 91.020  94.447  88.127  1.00 33.47  ? 190 PRO B N   1 
ATOM   3487  C  CA  . PRO B 1 190 ? 91.788  95.638  88.562  1.00 33.80  ? 190 PRO B CA  1 
ATOM   3488  C  C   . PRO B 1 190 ? 93.295  95.493  88.411  1.00 34.43  ? 190 PRO B C   1 
ATOM   3489  O  O   . PRO B 1 190 ? 93.955  96.404  87.901  1.00 36.34  ? 190 PRO B O   1 
ATOM   3490  C  CB  . PRO B 1 190 ? 91.385  95.800  90.034  1.00 32.06  ? 190 PRO B CB  1 
ATOM   3491  C  CG  . PRO B 1 190 ? 90.162  94.965  90.235  1.00 38.19  ? 190 PRO B CG  1 
ATOM   3492  C  CD  . PRO B 1 190 ? 90.134  93.909  89.173  1.00 34.26  ? 190 PRO B CD  1 
ATOM   3493  N  N   . GLU B 1 191 ? 93.863  94.368  88.831  1.00 32.33  ? 191 GLU B N   1 
ATOM   3494  C  CA  . GLU B 1 191 ? 95.306  94.196  88.760  1.00 37.12  ? 191 GLU B CA  1 
ATOM   3495  C  C   . GLU B 1 191 ? 95.748  93.643  87.404  1.00 30.53  ? 191 GLU B C   1 
ATOM   3496  O  O   . GLU B 1 191 ? 96.787  94.042  86.874  1.00 35.16  ? 191 GLU B O   1 
ATOM   3497  C  CB  . GLU B 1 191 ? 95.779  93.267  89.887  1.00 36.82  ? 191 GLU B CB  1 
ATOM   3498  C  CG  . GLU B 1 191 ? 95.185  93.531  91.306  1.00 39.92  ? 191 GLU B CG  1 
ATOM   3499  C  CD  . GLU B 1 191 ? 95.117  95.009  91.737  1.00 42.23  ? 191 GLU B CD  1 
ATOM   3500  O  OE1 . GLU B 1 191 ? 96.173  95.691  91.675  1.00 37.96  ? 191 GLU B OE1 1 
ATOM   3501  O  OE2 . GLU B 1 191 ? 94.022  95.462  92.193  1.00 34.51  ? 191 GLU B OE2 1 
ATOM   3502  N  N   . THR B 1 192 ? 94.982  92.719  86.834  1.00 34.75  ? 192 THR B N   1 
ATOM   3503  C  CA  . THR B 1 192 ? 95.368  92.070  85.583  1.00 32.17  ? 192 THR B CA  1 
ATOM   3504  C  C   . THR B 1 192 ? 95.092  92.929  84.350  1.00 31.08  ? 192 THR B C   1 
ATOM   3505  O  O   . THR B 1 192 ? 95.792  92.809  83.340  1.00 31.41  ? 192 THR B O   1 
ATOM   3506  C  CB  . THR B 1 192 ? 94.623  90.752  85.466  1.00 34.71  ? 192 THR B CB  1 
ATOM   3507  O  OG1 . THR B 1 192 ? 94.559  90.139  86.762  1.00 38.27  ? 192 THR B OG1 1 
ATOM   3508  C  CG2 . THR B 1 192 ? 95.281  89.831  84.445  1.00 31.11  ? 192 THR B CG2 1 
ATOM   3509  N  N   . GLY B 1 193 ? 94.093  93.792  84.400  1.00 30.78  ? 193 GLY B N   1 
ATOM   3510  C  CA  . GLY B 1 193 ? 93.639  94.467  83.208  1.00 30.07  ? 193 GLY B CA  1 
ATOM   3511  C  C   . GLY B 1 193 ? 92.669  93.611  82.414  1.00 31.67  ? 193 GLY B C   1 
ATOM   3512  O  O   . GLY B 1 193 ? 91.899  92.816  82.968  1.00 27.54  ? 193 GLY B O   1 
ATOM   3513  N  N   . PRO B 1 194 ? 92.682  93.773  81.091  1.00 31.32  ? 194 PRO B N   1 
ATOM   3514  C  CA  . PRO B 1 194 ? 91.717  93.056  80.248  1.00 25.44  ? 194 PRO B CA  1 
ATOM   3515  C  C   . PRO B 1 194 ? 92.105  91.606  79.983  1.00 28.45  ? 194 PRO B C   1 
ATOM   3516  O  O   . PRO B 1 194 ? 93.267  91.281  79.711  1.00 23.80  ? 194 PRO B O   1 
ATOM   3517  C  CB  . PRO B 1 194 ? 91.708  93.876  78.948  1.00 29.02  ? 194 PRO B CB  1 
ATOM   3518  C  CG  . PRO B 1 194 ? 93.003  94.609  78.937  1.00 29.15  ? 194 PRO B CG  1 
ATOM   3519  C  CD  . PRO B 1 194 ? 93.385  94.846  80.367  1.00 27.14  ? 194 PRO B CD  1 
ATOM   3520  N  N   . VAL B 1 195 ? 91.097  90.732  80.045  1.00 24.63  ? 195 VAL B N   1 
ATOM   3521  C  CA  . VAL B 1 195 ? 91.241  89.309  79.733  1.00 24.85  ? 195 VAL B CA  1 
ATOM   3522  C  C   . VAL B 1 195 ? 90.151  88.939  78.730  1.00 26.38  ? 195 VAL B C   1 
ATOM   3523  O  O   . VAL B 1 195 ? 88.958  89.150  78.999  1.00 25.24  ? 195 VAL B O   1 
ATOM   3524  C  CB  . VAL B 1 195 ? 91.156  88.425  80.995  1.00 27.03  ? 195 VAL B CB  1 
ATOM   3525  C  CG1 . VAL B 1 195 ? 91.192  86.948  80.643  1.00 25.79  ? 195 VAL B CG1 1 
ATOM   3526  C  CG2 . VAL B 1 195 ? 92.284  88.767  81.957  1.00 24.50  ? 195 VAL B CG2 1 
ATOM   3527  N  N   . LEU B 1 196 ? 90.556  88.405  77.569  1.00 25.32  ? 196 LEU B N   1 
ATOM   3528  C  CA  . LEU B 1 196 ? 89.621  88.020  76.502  1.00 25.73  ? 196 LEU B CA  1 
ATOM   3529  C  C   . LEU B 1 196 ? 89.463  86.498  76.494  1.00 28.73  ? 196 LEU B C   1 
ATOM   3530  O  O   . LEU B 1 196 ? 90.357  85.760  76.059  1.00 27.33  ? 196 LEU B O   1 
ATOM   3531  C  CB  . LEU B 1 196 ? 90.086  88.545  75.145  1.00 24.64  ? 196 LEU B CB  1 
ATOM   3532  C  CG  . LEU B 1 196 ? 89.301  88.194  73.873  1.00 26.50  ? 196 LEU B CG  1 
ATOM   3533  C  CD1 . LEU B 1 196 ? 87.833  88.555  74.004  1.00 28.31  ? 196 LEU B CD1 1 
ATOM   3534  C  CD2 . LEU B 1 196 ? 89.914  88.907  72.667  1.00 24.59  ? 196 LEU B CD2 1 
ATOM   3535  N  N   . LEU B 1 197 ? 88.315  86.033  76.979  1.00 22.49  ? 197 LEU B N   1 
ATOM   3536  C  CA  . LEU B 1 197 ? 87.938  84.626  76.893  1.00 23.39  ? 197 LEU B CA  1 
ATOM   3537  C  C   . LEU B 1 197 ? 87.347  84.389  75.504  1.00 27.89  ? 197 LEU B C   1 
ATOM   3538  O  O   . LEU B 1 197 ? 86.179  84.686  75.239  1.00 28.46  ? 197 LEU B O   1 
ATOM   3539  C  CB  . LEU B 1 197 ? 86.950  84.263  77.998  1.00 23.39  ? 197 LEU B CB  1 
ATOM   3540  C  CG  . LEU B 1 197 ? 87.377  84.621  79.434  1.00 27.11  ? 197 LEU B CG  1 
ATOM   3541  C  CD1 . LEU B 1 197 ? 86.332  84.180  80.466  1.00 20.84  ? 197 LEU B CD1 1 
ATOM   3542  C  CD2 . LEU B 1 197 ? 88.759  84.033  79.760  1.00 23.71  ? 197 LEU B CD2 1 
ATOM   3543  N  N   . ALA B 1 198 ? 88.158  83.854  74.605  1.00 24.87  ? 198 ALA B N   1 
ATOM   3544  C  CA  . ALA B 1 198 ? 87.675  83.623  73.258  1.00 26.12  ? 198 ALA B CA  1 
ATOM   3545  C  C   . ALA B 1 198 ? 86.647  82.504  73.223  1.00 27.76  ? 198 ALA B C   1 
ATOM   3546  O  O   . ALA B 1 198 ? 85.741  82.527  72.379  1.00 27.66  ? 198 ALA B O   1 
ATOM   3547  C  CB  . ALA B 1 198 ? 88.852  83.312  72.337  1.00 28.79  ? 198 ALA B CB  1 
ATOM   3548  N  N   . VAL B 1 199 ? 86.751  81.544  74.150  1.00 27.41  ? 199 VAL B N   1 
ATOM   3549  C  CA  . VAL B 1 199 ? 85.946  80.326  74.163  1.00 23.79  ? 199 VAL B CA  1 
ATOM   3550  C  C   . VAL B 1 199 ? 86.059  79.667  72.789  1.00 30.52  ? 199 VAL B C   1 
ATOM   3551  O  O   . VAL B 1 199 ? 87.169  79.549  72.248  1.00 24.71  ? 199 VAL B O   1 
ATOM   3552  C  CB  . VAL B 1 199 ? 84.502  80.640  74.600  1.00 26.93  ? 199 VAL B CB  1 
ATOM   3553  C  CG1 . VAL B 1 199 ? 83.748  79.372  74.977  1.00 26.10  ? 199 VAL B CG1 1 
ATOM   3554  C  CG2 . VAL B 1 199 ? 84.562  81.573  75.830  1.00 23.96  ? 199 VAL B CG2 1 
ATOM   3555  N  N   . ASP B 1 200 ? 84.941  79.261  72.189  1.00 25.96  ? 200 ASP B N   1 
ATOM   3556  C  CA  . ASP B 1 200 ? 85.012  78.455  70.981  1.00 26.19  ? 200 ASP B CA  1 
ATOM   3557  C  C   . ASP B 1 200 ? 85.060  79.271  69.698  1.00 28.81  ? 200 ASP B C   1 
ATOM   3558  O  O   . ASP B 1 200 ? 85.019  78.686  68.607  1.00 27.10  ? 200 ASP B O   1 
ATOM   3559  C  CB  . ASP B 1 200 ? 83.856  77.463  70.948  1.00 26.44  ? 200 ASP B CB  1 
ATOM   3560  C  CG  . ASP B 1 200 ? 84.086  76.313  71.903  1.00 30.56  ? 200 ASP B CG  1 
ATOM   3561  O  OD1 . ASP B 1 200 ? 85.115  76.318  72.613  1.00 28.66  ? 200 ASP B OD1 1 
ATOM   3562  O  OD2 . ASP B 1 200 ? 83.262  75.401  71.941  1.00 29.15  ? 200 ASP B OD2 1 
ATOM   3563  N  N   . ALA B 1 201 ? 85.144  80.601  69.796  1.00 27.59  ? 201 ALA B N   1 
ATOM   3564  C  CA  . ALA B 1 201 ? 85.464  81.400  68.623  1.00 21.12  ? 201 ALA B CA  1 
ATOM   3565  C  C   . ALA B 1 201 ? 86.898  81.168  68.148  1.00 24.78  ? 201 ALA B C   1 
ATOM   3566  O  O   . ALA B 1 201 ? 87.191  81.399  66.974  1.00 23.33  ? 201 ALA B O   1 
ATOM   3567  C  CB  . ALA B 1 201 ? 85.246  82.892  68.914  1.00 20.64  ? 201 ALA B CB  1 
ATOM   3568  N  N   . ALA B 1 202 ? 87.787  80.695  69.025  1.00 27.43  ? 202 ALA B N   1 
ATOM   3569  C  CA  . ALA B 1 202 ? 89.180  80.393  68.660  1.00 26.22  ? 202 ALA B CA  1 
ATOM   3570  C  C   . ALA B 1 202 ? 89.648  79.258  69.570  1.00 30.45  ? 202 ALA B C   1 
ATOM   3571  O  O   . ALA B 1 202 ? 90.099  79.498  70.694  1.00 28.38  ? 202 ALA B O   1 
ATOM   3572  C  CB  . ALA B 1 202 ? 90.074  81.615  68.793  1.00 27.48  ? 202 ALA B CB  1 
ATOM   3573  N  N   . TYR B 1 203 ? 89.495  78.022  69.081  1.00 30.74  ? 203 TYR B N   1 
ATOM   3574  C  CA  . TYR B 1 203 ? 89.882  76.837  69.843  1.00 33.78  ? 203 TYR B CA  1 
ATOM   3575  C  C   . TYR B 1 203 ? 91.329  76.922  70.308  1.00 36.26  ? 203 TYR B C   1 
ATOM   3576  O  O   . TYR B 1 203 ? 91.644  76.634  71.473  1.00 31.46  ? 203 TYR B O   1 
ATOM   3577  C  CB  . TYR B 1 203 ? 89.725  75.579  68.986  1.00 35.20  ? 203 TYR B CB  1 
ATOM   3578  C  CG  . TYR B 1 203 ? 88.336  74.988  68.824  1.00 36.17  ? 203 TYR B CG  1 
ATOM   3579  C  CD1 . TYR B 1 203 ? 87.341  75.170  69.771  1.00 37.85  ? 203 TYR B CD1 1 
ATOM   3580  C  CD2 . TYR B 1 203 ? 88.059  74.179  67.737  1.00 41.80  ? 203 TYR B CD2 1 
ATOM   3581  C  CE1 . TYR B 1 203 ? 86.084  74.586  69.609  1.00 32.96  ? 203 TYR B CE1 1 
ATOM   3582  C  CE2 . TYR B 1 203 ? 86.830  73.600  67.568  1.00 44.88  ? 203 TYR B CE2 1 
ATOM   3583  C  CZ  . TYR B 1 203 ? 85.844  73.799  68.503  1.00 40.77  ? 203 TYR B CZ  1 
ATOM   3584  O  OH  . TYR B 1 203 ? 84.624  73.188  68.301  1.00 45.21  ? 203 TYR B OH  1 
ATOM   3585  N  N   . THR B 1 204 ? 92.223  77.292  69.383  1.00 34.13  ? 204 THR B N   1 
ATOM   3586  C  CA  . THR B 1 204 ? 93.665  77.155  69.532  1.00 35.28  ? 204 THR B CA  1 
ATOM   3587  C  C   . THR B 1 204 ? 94.344  78.380  68.938  1.00 35.23  ? 204 THR B C   1 
ATOM   3588  O  O   . THR B 1 204 ? 93.719  79.207  68.267  1.00 34.65  ? 204 THR B O   1 
ATOM   3589  C  CB  . THR B 1 204 ? 94.217  75.899  68.820  1.00 37.46  ? 204 THR B CB  1 
ATOM   3590  O  OG1 . THR B 1 204 ? 94.139  76.090  67.404  1.00 34.85  ? 204 THR B OG1 1 
ATOM   3591  C  CG2 . THR B 1 204 ? 93.461  74.635  69.201  1.00 35.18  ? 204 THR B CG2 1 
ATOM   3592  N  N   . THR B 1 205 ? 95.657  78.461  69.163  1.00 36.75  ? 205 THR B N   1 
ATOM   3593  C  CA  . THR B 1 205 ? 96.474  79.509  68.561  1.00 34.82  ? 205 THR B CA  1 
ATOM   3594  C  C   . THR B 1 205 ? 96.484  79.421  67.036  1.00 33.54  ? 205 THR B C   1 
ATOM   3595  O  O   . THR B 1 205 ? 96.600  80.449  66.362  1.00 32.76  ? 205 THR B O   1 
ATOM   3596  C  CB  . THR B 1 205 ? 97.907  79.421  69.103  1.00 43.10  ? 205 THR B CB  1 
ATOM   3597  O  OG1 . THR B 1 205 ? 98.322  78.048  69.130  1.00 41.48  ? 205 THR B OG1 1 
ATOM   3598  C  CG2 . THR B 1 205 ? 98.004  79.978  70.519  1.00 38.77  ? 205 THR B CG2 1 
ATOM   3599  N  N   . ASP B 1 206 ? 96.408  78.208  66.475  1.00 33.56  ? 206 ASP B N   1 
ATOM   3600  C  CA  . ASP B 1 206 ? 96.335  78.056  65.019  1.00 36.08  ? 206 ASP B CA  1 
ATOM   3601  C  C   . ASP B 1 206 ? 95.058  78.675  64.445  1.00 35.42  ? 206 ASP B C   1 
ATOM   3602  O  O   . ASP B 1 206 ? 95.067  79.213  63.333  1.00 34.75  ? 206 ASP B O   1 
ATOM   3603  C  CB  . ASP B 1 206 ? 96.402  76.579  64.641  1.00 40.84  ? 206 ASP B CB  1 
ATOM   3604  C  CG  . ASP B 1 206 ? 97.812  76.009  64.735  1.00 46.38  ? 206 ASP B CG  1 
ATOM   3605  O  OD1 . ASP B 1 206 ? 98.776  76.794  64.901  1.00 43.51  ? 206 ASP B OD1 1 
ATOM   3606  O  OD2 . ASP B 1 206 ? 97.946  74.767  64.636  1.00 45.55  ? 206 ASP B OD2 1 
ATOM   3607  N  N   . HIS B 1 207 ? 93.933  78.554  65.154  1.00 33.88  ? 207 HIS B N   1 
ATOM   3608  C  CA  . HIS B 1 207 ? 92.723  79.242  64.709  1.00 34.61  ? 207 HIS B CA  1 
ATOM   3609  C  C   . HIS B 1 207 ? 92.917  80.744  64.799  1.00 31.03  ? 207 HIS B C   1 
ATOM   3610  O  O   . HIS B 1 207 ? 92.667  81.478  63.835  1.00 30.51  ? 207 HIS B O   1 
ATOM   3611  C  CB  . HIS B 1 207 ? 91.522  78.791  65.549  1.00 29.61  ? 207 HIS B CB  1 
ATOM   3612  C  CG  . HIS B 1 207 ? 91.224  77.332  65.411  1.00 35.44  ? 207 HIS B CG  1 
ATOM   3613  N  ND1 . HIS B 1 207 ? 91.674  76.389  66.312  1.00 35.21  ? 207 HIS B ND1 1 
ATOM   3614  C  CD2 . HIS B 1 207 ? 90.555  76.647  64.451  1.00 35.67  ? 207 HIS B CD2 1 
ATOM   3615  C  CE1 . HIS B 1 207 ? 91.276  75.190  65.926  1.00 41.05  ? 207 HIS B CE1 1 
ATOM   3616  N  NE2 . HIS B 1 207 ? 90.601  75.317  64.796  1.00 41.93  ? 207 HIS B NE2 1 
ATOM   3617  N  N   . TRP B 1 208 ? 93.413  81.205  65.949  1.00 28.63  ? 208 TRP B N   1 
ATOM   3618  C  CA  . TRP B 1 208 ? 93.698  82.616  66.129  1.00 30.13  ? 208 TRP B CA  1 
ATOM   3619  C  C   . TRP B 1 208 ? 94.598  83.144  65.022  1.00 30.74  ? 208 TRP B C   1 
ATOM   3620  O  O   . TRP B 1 208 ? 94.378  84.253  64.519  1.00 34.04  ? 208 TRP B O   1 
ATOM   3621  C  CB  . TRP B 1 208 ? 94.322  82.840  67.507  1.00 30.00  ? 208 TRP B CB  1 
ATOM   3622  C  CG  . TRP B 1 208 ? 94.559  84.282  67.836  1.00 31.62  ? 208 TRP B CG  1 
ATOM   3623  C  CD1 . TRP B 1 208 ? 95.708  84.985  67.608  1.00 32.17  ? 208 TRP B CD1 1 
ATOM   3624  C  CD2 . TRP B 1 208 ? 93.650  85.190  68.471  1.00 27.22  ? 208 TRP B CD2 1 
ATOM   3625  N  NE1 . TRP B 1 208 ? 95.570  86.274  68.058  1.00 33.15  ? 208 TRP B NE1 1 
ATOM   3626  C  CE2 . TRP B 1 208 ? 94.318  86.430  68.592  1.00 28.62  ? 208 TRP B CE2 1 
ATOM   3627  C  CE3 . TRP B 1 208 ? 92.341  85.081  68.949  1.00 29.78  ? 208 TRP B CE3 1 
ATOM   3628  C  CZ2 . TRP B 1 208 ? 93.713  87.555  69.153  1.00 27.65  ? 208 TRP B CZ2 1 
ATOM   3629  C  CZ3 . TRP B 1 208 ? 91.741  86.200  69.511  1.00 26.45  ? 208 TRP B CZ3 1 
ATOM   3630  C  CH2 . TRP B 1 208 ? 92.423  87.419  69.609  1.00 26.47  ? 208 TRP B CH2 1 
ATOM   3631  N  N   . ASP B 1 209 ? 95.590  82.350  64.602  1.00 32.79  ? 209 ASP B N   1 
ATOM   3632  C  CA  . ASP B 1 209 ? 96.565  82.757  63.594  1.00 33.81  ? 209 ASP B CA  1 
ATOM   3633  C  C   . ASP B 1 209 ? 96.112  82.462  62.165  1.00 34.98  ? 209 ASP B C   1 
ATOM   3634  O  O   . ASP B 1 209 ? 96.891  82.674  61.224  1.00 31.71  ? 209 ASP B O   1 
ATOM   3635  C  CB  . ASP B 1 209 ? 97.915  82.073  63.854  1.00 37.61  ? 209 ASP B CB  1 
ATOM   3636  C  CG  . ASP B 1 209 ? 98.529  82.454  65.195  1.00 39.14  ? 209 ASP B CG  1 
ATOM   3637  O  OD1 . ASP B 1 209 ? 98.078  83.440  65.811  1.00 38.77  ? 209 ASP B OD1 1 
ATOM   3638  O  OD2 . ASP B 1 209 ? 99.464  81.752  65.635  1.00 42.50  ? 209 ASP B OD2 1 
ATOM   3639  N  N   . GLU B 1 210 ? 94.887  81.964  61.983  1.00 31.37  ? 210 GLU B N   1 
ATOM   3640  C  CA  . GLU B 1 210 ? 94.332  81.704  60.654  1.00 32.48  ? 210 GLU B CA  1 
ATOM   3641  C  C   . GLU B 1 210 ? 95.122  80.617  59.913  1.00 38.01  ? 210 GLU B C   1 
ATOM   3642  O  O   . GLU B 1 210 ? 95.244  80.637  58.685  1.00 36.73  ? 210 GLU B O   1 
ATOM   3643  C  CB  . GLU B 1 210 ? 94.244  83.003  59.843  1.00 29.03  ? 210 GLU B CB  1 
ATOM   3644  C  CG  . GLU B 1 210 ? 93.356  84.057  60.542  1.00 32.38  ? 210 GLU B CG  1 
ATOM   3645  C  CD  . GLU B 1 210 ? 93.164  85.350  59.765  1.00 32.71  ? 210 GLU B CD  1 
ATOM   3646  O  OE1 . GLU B 1 210 ? 93.848  85.558  58.743  1.00 33.96  ? 210 GLU B OE1 1 
ATOM   3647  O  OE2 . GLU B 1 210 ? 92.301  86.162  60.169  1.00 34.00  ? 210 GLU B OE2 1 
ATOM   3648  N  N   . LYS B 1 211 ? 95.659  79.651  60.660  1.00 37.47  ? 211 LYS B N   1 
ATOM   3649  C  CA  . LYS B 1 211 ? 96.247  78.450  60.081  1.00 46.30  ? 211 LYS B CA  1 
ATOM   3650  C  C   . LYS B 1 211 ? 95.326  77.238  60.197  1.00 45.60  ? 211 LYS B C   1 
ATOM   3651  O  O   . LYS B 1 211 ? 95.721  76.135  59.806  1.00 49.54  ? 211 LYS B O   1 
ATOM   3652  C  CB  . LYS B 1 211 ? 97.603  78.136  60.741  1.00 44.96  ? 211 LYS B CB  1 
ATOM   3653  C  CG  . LYS B 1 211 ? 98.743  79.160  60.519  1.00 37.96  ? 211 LYS B CG  1 
ATOM   3654  C  CD  . LYS B 1 211 ? 98.509  80.105  59.339  1.00 55.10  ? 211 LYS B CD  1 
ATOM   3655  C  CE  . LYS B 1 211 ? 99.064  79.580  58.010  1.00 57.82  ? 211 LYS B CE  1 
ATOM   3656  N  NZ  . LYS B 1 211 ? 98.886  80.589  56.917  1.00 60.57  ? 211 LYS B NZ  1 
ATOM   3657  N  N   . ALA B 1 212 ? 94.108  77.419  60.709  1.00 34.67  ? 212 ALA B N   1 
ATOM   3658  C  CA  . ALA B 1 212 ? 93.150  76.338  60.879  1.00 35.89  ? 212 ALA B CA  1 
ATOM   3659  C  C   . ALA B 1 212 ? 91.743  76.919  60.921  1.00 36.42  ? 212 ALA B C   1 
ATOM   3660  O  O   . ALA B 1 212 ? 91.545  78.062  61.340  1.00 34.27  ? 212 ALA B O   1 
ATOM   3661  C  CB  . ALA B 1 212 ? 93.418  75.556  62.168  1.00 37.78  ? 212 ALA B CB  1 
ATOM   3662  N  N   . LEU B 1 213 ? 90.767  76.121  60.481  1.00 34.80  ? 213 LEU B N   1 
ATOM   3663  C  CA  . LEU B 1 213 ? 89.357  76.400  60.702  1.00 38.20  ? 213 LEU B CA  1 
ATOM   3664  C  C   . LEU B 1 213 ? 88.806  75.452  61.765  1.00 38.66  ? 213 LEU B C   1 
ATOM   3665  O  O   . LEU B 1 213 ? 89.292  74.327  61.911  1.00 38.00  ? 213 LEU B O   1 
ATOM   3666  C  CB  . LEU B 1 213 ? 88.532  76.230  59.419  1.00 35.12  ? 213 LEU B CB  1 
ATOM   3667  C  CG  . LEU B 1 213 ? 88.766  77.237  58.303  1.00 37.40  ? 213 LEU B CG  1 
ATOM   3668  C  CD1 . LEU B 1 213 ? 87.957  76.855  57.064  1.00 33.60  ? 213 LEU B CD1 1 
ATOM   3669  C  CD2 . LEU B 1 213 ? 88.413  78.618  58.779  1.00 32.60  ? 213 LEU B CD2 1 
ATOM   3670  N  N   . PRO B 1 214 ? 87.778  75.853  62.505  1.00 36.21  ? 214 PRO B N   1 
ATOM   3671  C  CA  . PRO B 1 214 ? 87.206  74.938  63.501  1.00 40.34  ? 214 PRO B CA  1 
ATOM   3672  C  C   . PRO B 1 214 ? 86.634  73.693  62.836  1.00 43.02  ? 214 PRO B C   1 
ATOM   3673  O  O   . PRO B 1 214 ? 86.102  73.745  61.723  1.00 41.02  ? 214 PRO B O   1 
ATOM   3674  C  CB  . PRO B 1 214 ? 86.106  75.776  64.173  1.00 38.88  ? 214 PRO B CB  1 
ATOM   3675  C  CG  . PRO B 1 214 ? 86.374  77.194  63.771  1.00 38.39  ? 214 PRO B CG  1 
ATOM   3676  C  CD  . PRO B 1 214 ? 87.018  77.108  62.414  1.00 36.71  ? 214 PRO B CD  1 
ATOM   3677  N  N   . GLY B 1 215 ? 86.764  72.559  63.528  1.00 44.22  ? 215 GLY B N   1 
ATOM   3678  C  CA  . GLY B 1 215 ? 86.248  71.309  63.000  1.00 45.80  ? 215 GLY B CA  1 
ATOM   3679  C  C   . GLY B 1 215 ? 84.745  71.155  63.122  1.00 43.46  ? 215 GLY B C   1 
ATOM   3680  O  O   . GLY B 1 215 ? 84.169  70.284  62.464  1.00 46.86  ? 215 GLY B O   1 
ATOM   3681  N  N   . PHE B 1 216 ? 84.101  71.961  63.961  1.00 43.24  ? 216 PHE B N   1 
ATOM   3682  C  CA  . PHE B 1 216 ? 82.648  72.009  64.051  1.00 44.28  ? 216 PHE B CA  1 
ATOM   3683  C  C   . PHE B 1 216 ? 82.213  73.462  63.876  1.00 42.34  ? 216 PHE B C   1 
ATOM   3684  O  O   . PHE B 1 216 ? 82.798  74.370  64.476  1.00 41.67  ? 216 PHE B O   1 
ATOM   3685  C  CB  . PHE B 1 216 ? 82.144  71.422  65.385  1.00 42.64  ? 216 PHE B CB  1 
ATOM   3686  C  CG  . PHE B 1 216 ? 80.651  71.492  65.544  1.00 50.81  ? 216 PHE B CG  1 
ATOM   3687  C  CD1 . PHE B 1 216 ? 80.026  72.671  65.945  1.00 49.91  ? 216 PHE B CD1 1 
ATOM   3688  C  CD2 . PHE B 1 216 ? 79.865  70.396  65.226  1.00 52.51  ? 216 PHE B CD2 1 
ATOM   3689  C  CE1 . PHE B 1 216 ? 78.648  72.743  66.052  1.00 55.47  ? 216 PHE B CE1 1 
ATOM   3690  C  CE2 . PHE B 1 216 ? 78.487  70.461  65.342  1.00 50.10  ? 216 PHE B CE2 1 
ATOM   3691  C  CZ  . PHE B 1 216 ? 77.881  71.635  65.755  1.00 54.35  ? 216 PHE B CZ  1 
ATOM   3692  N  N   . LEU B 1 217 ? 81.166  73.679  63.079  1.00 36.54  ? 217 LEU B N   1 
ATOM   3693  C  CA  . LEU B 1 217 ? 80.975  74.972  62.436  1.00 35.75  ? 217 LEU B CA  1 
ATOM   3694  C  C   . LEU B 1 217 ? 79.520  75.181  62.048  1.00 33.88  ? 217 LEU B C   1 
ATOM   3695  O  O   . LEU B 1 217 ? 78.959  74.365  61.319  1.00 30.95  ? 217 LEU B O   1 
ATOM   3696  C  CB  . LEU B 1 217 ? 81.861  75.038  61.188  1.00 34.97  ? 217 LEU B CB  1 
ATOM   3697  C  CG  . LEU B 1 217 ? 82.539  76.369  60.999  1.00 32.28  ? 217 LEU B CG  1 
ATOM   3698  C  CD1 . LEU B 1 217 ? 83.487  76.545  62.131  1.00 39.75  ? 217 LEU B CD1 1 
ATOM   3699  C  CD2 . LEU B 1 217 ? 83.319  76.307  59.725  1.00 37.94  ? 217 LEU B CD2 1 
ATOM   3700  N  N   . ALA B 1 218 ? 78.927  76.284  62.502  1.00 27.85  ? 218 ALA B N   1 
ATOM   3701  C  CA  . ALA B 1 218 ? 77.667  76.712  61.905  1.00 25.76  ? 218 ALA B CA  1 
ATOM   3702  C  C   . ALA B 1 218 ? 77.907  77.525  60.634  1.00 26.37  ? 218 ALA B C   1 
ATOM   3703  O  O   . ALA B 1 218 ? 77.215  77.333  59.626  1.00 23.49  ? 218 ALA B O   1 
ATOM   3704  C  CB  . ALA B 1 218 ? 76.848  77.525  62.906  1.00 20.75  ? 218 ALA B CB  1 
ATOM   3705  N  N   . SER B 1 219 ? 78.865  78.450  60.672  1.00 23.83  ? 219 SER B N   1 
ATOM   3706  C  CA  . SER B 1 219 ? 79.161  79.295  59.522  1.00 23.91  ? 219 SER B CA  1 
ATOM   3707  C  C   . SER B 1 219 ? 80.650  79.593  59.495  1.00 24.99  ? 219 SER B C   1 
ATOM   3708  O  O   . SER B 1 219 ? 81.195  80.142  60.457  1.00 24.69  ? 219 SER B O   1 
ATOM   3709  C  CB  . SER B 1 219 ? 78.344  80.587  59.570  1.00 24.54  ? 219 SER B CB  1 
ATOM   3710  O  OG  . SER B 1 219 ? 78.812  81.533  58.630  1.00 26.96  ? 219 SER B OG  1 
ATOM   3711  N  N   . THR B 1 220 ? 81.303  79.226  58.396  1.00 25.09  ? 220 THR B N   1 
ATOM   3712  C  CA  . THR B 1 220 ? 82.712  79.555  58.234  1.00 24.43  ? 220 THR B CA  1 
ATOM   3713  C  C   . THR B 1 220 ? 82.907  81.053  58.047  1.00 25.38  ? 220 THR B C   1 
ATOM   3714  O  O   . THR B 1 220 ? 83.888  81.626  58.543  1.00 26.40  ? 220 THR B O   1 
ATOM   3715  C  CB  . THR B 1 220 ? 83.290  78.788  57.047  1.00 29.83  ? 220 THR B CB  1 
ATOM   3716  O  OG1 . THR B 1 220 ? 82.693  77.479  56.972  1.00 32.57  ? 220 THR B OG1 1 
ATOM   3717  C  CG2 . THR B 1 220 ? 84.803  78.656  57.196  1.00 28.50  ? 220 THR B CG2 1 
ATOM   3718  N  N   . VAL B 1 221 ? 81.986  81.701  57.327  1.00 25.01  ? 221 VAL B N   1 
ATOM   3719  C  CA  . VAL B 1 221 ? 82.094  83.141  57.089  1.00 25.54  ? 221 VAL B CA  1 
ATOM   3720  C  C   . VAL B 1 221 ? 82.075  83.907  58.414  1.00 22.78  ? 221 VAL B C   1 
ATOM   3721  O  O   . VAL B 1 221 ? 82.970  84.713  58.695  1.00 20.34  ? 221 VAL B O   1 
ATOM   3722  C  CB  . VAL B 1 221 ? 80.982  83.608  56.124  1.00 24.78  ? 221 VAL B CB  1 
ATOM   3723  C  CG1 . VAL B 1 221 ? 80.858  85.107  56.124  1.00 21.76  ? 221 VAL B CG1 1 
ATOM   3724  C  CG2 . VAL B 1 221 ? 81.288  83.119  54.703  1.00 25.26  ? 221 VAL B CG2 1 
ATOM   3725  N  N   . ASP B 1 222 ? 81.064  83.653  59.255  1.00 22.31  ? 222 ASP B N   1 
ATOM   3726  C  CA  . ASP B 1 222 ? 80.989  84.322  60.551  1.00 19.64  ? 222 ASP B CA  1 
ATOM   3727  C  C   . ASP B 1 222 ? 82.192  83.982  61.423  1.00 20.72  ? 222 ASP B C   1 
ATOM   3728  O  O   . ASP B 1 222 ? 82.739  84.856  62.107  1.00 19.44  ? 222 ASP B O   1 
ATOM   3729  C  CB  . ASP B 1 222 ? 79.707  83.923  61.285  1.00 20.48  ? 222 ASP B CB  1 
ATOM   3730  C  CG  . ASP B 1 222 ? 78.448  84.475  60.625  1.00 25.46  ? 222 ASP B CG  1 
ATOM   3731  O  OD1 . ASP B 1 222 ? 78.522  85.529  59.946  1.00 23.19  ? 222 ASP B OD1 1 
ATOM   3732  O  OD2 . ASP B 1 222 ? 77.389  83.839  60.791  1.00 22.35  ? 222 ASP B OD2 1 
ATOM   3733  N  N   . ALA B 1 223 ? 82.599  82.710  61.431  1.00 22.08  ? 223 ALA B N   1 
ATOM   3734  C  CA  . ALA B 1 223 ? 83.644  82.265  62.349  1.00 22.56  ? 223 ALA B CA  1 
ATOM   3735  C  C   . ALA B 1 223 ? 84.958  82.988  62.078  1.00 21.52  ? 223 ALA B C   1 
ATOM   3736  O  O   . ALA B 1 223 ? 85.616  83.468  63.007  1.00 23.79  ? 223 ALA B O   1 
ATOM   3737  C  CB  . ALA B 1 223 ? 83.825  80.747  62.258  1.00 20.32  ? 223 ALA B CB  1 
ATOM   3738  N  N   . VAL B 1 224 ? 85.348  83.099  60.807  1.00 20.64  ? 224 VAL B N   1 
ATOM   3739  C  CA  . VAL B 1 224 ? 86.608  83.791  60.523  1.00 22.72  ? 224 VAL B CA  1 
ATOM   3740  C  C   . VAL B 1 224 ? 86.480  85.294  60.750  1.00 25.40  ? 224 VAL B C   1 
ATOM   3741  O  O   . VAL B 1 224 ? 87.447  85.949  61.161  1.00 27.08  ? 224 VAL B O   1 
ATOM   3742  C  CB  . VAL B 1 224 ? 87.097  83.488  59.099  1.00 21.19  ? 224 VAL B CB  1 
ATOM   3743  C  CG1 . VAL B 1 224 ? 87.385  81.996  58.964  1.00 24.78  ? 224 VAL B CG1 1 
ATOM   3744  C  CG2 . VAL B 1 224 ? 86.094  83.977  58.057  1.00 21.18  ? 224 VAL B CG2 1 
ATOM   3745  N  N   . ARG B 1 225 ? 85.304  85.875  60.491  1.00 24.59  ? 225 ARG B N   1 
ATOM   3746  C  CA  . ARG B 1 225 ? 85.132  87.294  60.785  1.00 23.00  ? 225 ARG B CA  1 
ATOM   3747  C  C   . ARG B 1 225 ? 85.098  87.544  62.289  1.00 22.28  ? 225 ARG B C   1 
ATOM   3748  O  O   . ARG B 1 225 ? 85.591  88.571  62.761  1.00 23.01  ? 225 ARG B O   1 
ATOM   3749  C  CB  . ARG B 1 225 ? 83.865  87.816  60.120  1.00 24.87  ? 225 ARG B CB  1 
ATOM   3750  C  CG  . ARG B 1 225 ? 84.001  87.833  58.610  1.00 26.42  ? 225 ARG B CG  1 
ATOM   3751  C  CD  . ARG B 1 225 ? 82.734  88.267  57.928  1.00 21.85  ? 225 ARG B CD  1 
ATOM   3752  N  NE  . ARG B 1 225 ? 82.904  88.085  56.499  1.00 26.09  ? 225 ARG B NE  1 
ATOM   3753  C  CZ  . ARG B 1 225 ? 82.021  88.451  55.582  1.00 24.97  ? 225 ARG B CZ  1 
ATOM   3754  N  NH1 . ARG B 1 225 ? 80.865  88.998  55.922  1.00 21.51  ? 225 ARG B NH1 1 
ATOM   3755  N  NH2 . ARG B 1 225 ? 82.310  88.267  54.293  1.00 21.24  ? 225 ARG B NH2 1 
ATOM   3756  N  N   . SER B 1 226 ? 84.522  86.613  63.055  1.00 20.15  ? 226 SER B N   1 
ATOM   3757  C  CA  . SER B 1 226 ? 84.545  86.747  64.508  1.00 23.50  ? 226 SER B CA  1 
ATOM   3758  C  C   . SER B 1 226 ? 85.975  86.669  65.041  1.00 20.86  ? 226 SER B C   1 
ATOM   3759  O  O   . SER B 1 226 ? 86.330  87.369  65.999  1.00 20.64  ? 226 SER B O   1 
ATOM   3760  C  CB  . SER B 1 226 ? 83.665  85.670  65.148  1.00 17.41  ? 226 SER B CB  1 
ATOM   3761  O  OG  . SER B 1 226 ? 82.288  85.933  64.920  1.00 17.87  ? 226 SER B OG  1 
ATOM   3762  N  N   . VAL B 1 227 ? 86.818  85.842  64.419  1.00 21.41  ? 227 VAL B N   1 
ATOM   3763  C  CA  . VAL B 1 227 ? 88.208  85.796  64.851  1.00 22.71  ? 227 VAL B CA  1 
ATOM   3764  C  C   . VAL B 1 227 ? 88.887  87.127  64.573  1.00 21.78  ? 227 VAL B C   1 
ATOM   3765  O  O   . VAL B 1 227 ? 89.647  87.627  65.401  1.00 25.00  ? 227 VAL B O   1 
ATOM   3766  C  CB  . VAL B 1 227 ? 88.957  84.620  64.199  1.00 24.15  ? 227 VAL B CB  1 
ATOM   3767  C  CG1 . VAL B 1 227 ? 90.479  84.826  64.332  1.00 23.24  ? 227 VAL B CG1 1 
ATOM   3768  C  CG2 . VAL B 1 227 ? 88.526  83.296  64.839  1.00 19.93  ? 227 VAL B CG2 1 
ATOM   3769  N  N   . ARG B 1 228 ? 88.600  87.751  63.433  1.00 21.12  ? 228 ARG B N   1 
ATOM   3770  C  CA  . ARG B 1 228 ? 89.258  89.029  63.175  1.00 26.23  ? 228 ARG B CA  1 
ATOM   3771  C  C   . ARG B 1 228 ? 88.683  90.144  64.046  1.00 29.33  ? 228 ARG B C   1 
ATOM   3772  O  O   . ARG B 1 228 ? 89.401  91.096  64.375  1.00 26.42  ? 228 ARG B O   1 
ATOM   3773  C  CB  . ARG B 1 228 ? 89.175  89.396  61.696  1.00 28.19  ? 228 ARG B CB  1 
ATOM   3774  C  CG  . ARG B 1 228 ? 89.965  88.439  60.822  1.00 29.87  ? 228 ARG B CG  1 
ATOM   3775  C  CD  . ARG B 1 228 ? 90.433  89.066  59.519  1.00 26.63  ? 228 ARG B CD  1 
ATOM   3776  N  NE  . ARG B 1 228 ? 91.391  88.188  58.860  1.00 29.05  ? 228 ARG B NE  1 
ATOM   3777  C  CZ  . ARG B 1 228 ? 91.850  88.365  57.628  1.00 33.21  ? 228 ARG B CZ  1 
ATOM   3778  N  NH1 . ARG B 1 228 ? 91.471  89.399  56.889  1.00 34.26  ? 228 ARG B NH1 1 
ATOM   3779  N  NH2 . ARG B 1 228 ? 92.712  87.486  57.123  1.00 31.74  ? 228 ARG B NH2 1 
ATOM   3780  N  N   . LYS B 1 229 ? 87.405  90.035  64.437  1.00 23.80  ? 229 LYS B N   1 
ATOM   3781  C  CA  . LYS B 1 229 ? 86.847  90.953  65.416  1.00 23.98  ? 229 LYS B CA  1 
ATOM   3782  C  C   . LYS B 1 229 ? 87.591  90.843  66.747  1.00 23.39  ? 229 LYS B C   1 
ATOM   3783  O  O   . LYS B 1 229 ? 87.908  91.854  67.379  1.00 25.21  ? 229 LYS B O   1 
ATOM   3784  C  CB  . LYS B 1 229 ? 85.353  90.656  65.593  1.00 20.72  ? 229 LYS B CB  1 
ATOM   3785  C  CG  . LYS B 1 229 ? 84.688  91.406  66.723  1.00 21.11  ? 229 LYS B CG  1 
ATOM   3786  C  CD  . LYS B 1 229 ? 83.231  90.943  66.875  1.00 28.22  ? 229 LYS B CD  1 
ATOM   3787  C  CE  . LYS B 1 229 ? 82.405  91.847  67.804  1.00 25.03  ? 229 LYS B CE  1 
ATOM   3788  N  NZ  . LYS B 1 229 ? 80.978  91.357  67.825  1.00 27.74  ? 229 LYS B NZ  1 
ATOM   3789  N  N   . LEU B 1 230 ? 87.882  89.621  67.181  1.00 22.67  ? 230 LEU B N   1 
ATOM   3790  C  CA  . LEU B 1 230 ? 88.659  89.439  68.404  1.00 24.34  ? 230 LEU B CA  1 
ATOM   3791  C  C   . LEU B 1 230 ? 90.078  89.978  68.253  1.00 26.66  ? 230 LEU B C   1 
ATOM   3792  O  O   . LEU B 1 230 ? 90.641  90.532  69.212  1.00 26.50  ? 230 LEU B O   1 
ATOM   3793  C  CB  . LEU B 1 230 ? 88.689  87.963  68.789  1.00 24.14  ? 230 LEU B CB  1 
ATOM   3794  C  CG  . LEU B 1 230 ? 87.339  87.418  69.240  1.00 23.89  ? 230 LEU B CG  1 
ATOM   3795  C  CD1 . LEU B 1 230 ? 87.453  85.961  69.641  1.00 20.80  ? 230 LEU B CD1 1 
ATOM   3796  C  CD2 . LEU B 1 230 ? 86.761  88.276  70.360  1.00 21.75  ? 230 LEU B CD2 1 
ATOM   3797  N  N   . HIS B 1 231 ? 90.679  89.814  67.061  1.00 25.87  ? 231 HIS B N   1 
ATOM   3798  C  CA  . HIS B 1 231 ? 91.992  90.406  66.792  1.00 27.47  ? 231 HIS B CA  1 
ATOM   3799  C  C   . HIS B 1 231 ? 91.983  91.891  67.103  1.00 29.30  ? 231 HIS B C   1 
ATOM   3800  O  O   . HIS B 1 231 ? 92.845  92.392  67.836  1.00 27.88  ? 231 HIS B O   1 
ATOM   3801  C  CB  . HIS B 1 231 ? 92.406  90.226  65.330  1.00 24.23  ? 231 HIS B CB  1 
ATOM   3802  C  CG  . HIS B 1 231 ? 92.776  88.829  64.961  1.00 26.73  ? 231 HIS B CG  1 
ATOM   3803  N  ND1 . HIS B 1 231 ? 92.969  88.435  63.654  1.00 27.06  ? 231 HIS B ND1 1 
ATOM   3804  C  CD2 . HIS B 1 231 ? 93.003  87.735  65.724  1.00 27.27  ? 231 HIS B CD2 1 
ATOM   3805  C  CE1 . HIS B 1 231 ? 93.287  87.155  63.631  1.00 29.63  ? 231 HIS B CE1 1 
ATOM   3806  N  NE2 . HIS B 1 231 ? 93.314  86.707  64.873  1.00 28.08  ? 231 HIS B NE2 1 
ATOM   3807  N  N   . ALA B 1 232 ? 91.008  92.609  66.532  1.00 23.27  ? 232 ALA B N   1 
ATOM   3808  C  CA  . ALA B 1 232 ? 90.939  94.049  66.714  1.00 23.57  ? 232 ALA B CA  1 
ATOM   3809  C  C   . ALA B 1 232 ? 90.719  94.404  68.172  1.00 26.24  ? 232 ALA B C   1 
ATOM   3810  O  O   . ALA B 1 232 ? 91.259  95.401  68.659  1.00 26.59  ? 232 ALA B O   1 
ATOM   3811  C  CB  . ALA B 1 232 ? 89.820  94.644  65.855  1.00 26.40  ? 232 ALA B CB  1 
ATOM   3812  N  N   . LEU B 1 233 ? 89.917  93.602  68.881  1.00 26.15  ? 233 LEU B N   1 
ATOM   3813  C  CA  . LEU B 1 233 ? 89.654  93.866  70.291  1.00 25.40  ? 233 LEU B CA  1 
ATOM   3814  C  C   . LEU B 1 233 ? 90.905  93.639  71.141  1.00 26.87  ? 233 LEU B C   1 
ATOM   3815  O  O   . LEU B 1 233 ? 91.165  94.387  72.090  1.00 24.22  ? 233 LEU B O   1 
ATOM   3816  C  CB  . LEU B 1 233 ? 88.499  92.983  70.769  1.00 21.48  ? 233 LEU B CB  1 
ATOM   3817  C  CG  . LEU B 1 233 ? 88.011  93.110  72.222  1.00 28.30  ? 233 LEU B CG  1 
ATOM   3818  C  CD1 . LEU B 1 233 ? 87.603  94.542  72.553  1.00 25.89  ? 233 LEU B CD1 1 
ATOM   3819  C  CD2 . LEU B 1 233 ? 86.826  92.149  72.512  1.00 19.69  ? 233 LEU B CD2 1 
ATOM   3820  N  N   . ALA B 1 234 ? 91.680  92.603  70.823  1.00 26.39  ? 234 ALA B N   1 
ATOM   3821  C  CA  . ALA B 1 234 ? 92.881  92.328  71.597  1.00 28.37  ? 234 ALA B CA  1 
ATOM   3822  C  C   . ALA B 1 234 ? 93.955  93.363  71.304  1.00 27.50  ? 234 ALA B C   1 
ATOM   3823  O  O   . ALA B 1 234 ? 94.655  93.816  72.214  1.00 32.62  ? 234 ALA B O   1 
ATOM   3824  C  CB  . ALA B 1 234 ? 93.384  90.913  71.302  1.00 28.12  ? 234 ALA B CB  1 
ATOM   3825  N  N   . GLU B 1 235 ? 94.077  93.766  70.041  1.00 25.77  ? 235 GLU B N   1 
ATOM   3826  C  CA  . GLU B 1 235 ? 95.016  94.819  69.686  1.00 30.99  ? 235 GLU B CA  1 
ATOM   3827  C  C   . GLU B 1 235 ? 94.650  96.133  70.370  1.00 30.08  ? 235 GLU B C   1 
ATOM   3828  O  O   . GLU B 1 235 ? 95.529  96.856  70.853  1.00 31.14  ? 235 GLU B O   1 
ATOM   3829  C  CB  . GLU B 1 235 ? 95.051  94.991  68.168  1.00 28.48  ? 235 GLU B CB  1 
ATOM   3830  C  CG  . GLU B 1 235 ? 96.190  95.879  67.655  1.00 32.81  ? 235 GLU B CG  1 
ATOM   3831  C  CD  . GLU B 1 235 ? 95.887  97.378  67.733  1.00 32.93  ? 235 GLU B CD  1 
ATOM   3832  O  OE1 . GLU B 1 235 ? 94.696  97.770  67.790  1.00 30.17  ? 235 GLU B OE1 1 
ATOM   3833  O  OE2 . GLU B 1 235 ? 96.859  98.166  67.733  1.00 33.38  ? 235 GLU B OE2 1 
ATOM   3834  N  N   . LYS B 1 236 ? 93.358  96.453  70.427  1.00 25.68  ? 236 LYS B N   1 
ATOM   3835  C  CA  . LYS B 1 236 ? 92.917  97.697  71.048  1.00 29.18  ? 236 LYS B CA  1 
ATOM   3836  C  C   . LYS B 1 236 ? 93.140  97.689  72.558  1.00 29.41  ? 236 LYS B C   1 
ATOM   3837  O  O   . LYS B 1 236 ? 93.539  98.705  73.139  1.00 30.85  ? 236 LYS B O   1 
ATOM   3838  C  CB  . LYS B 1 236 ? 91.440  97.931  70.727  1.00 27.09  ? 236 LYS B CB  1 
ATOM   3839  C  CG  . LYS B 1 236 ? 90.728  98.908  71.662  1.00 27.35  ? 236 LYS B CG  1 
ATOM   3840  C  CD  . LYS B 1 236 ? 89.277  99.150  71.211  1.00 24.80  ? 236 LYS B CD  1 
ATOM   3841  C  CE  . LYS B 1 236 ? 88.523  100.030 72.204  1.00 23.98  ? 236 LYS B CE  1 
ATOM   3842  N  NZ  . LYS B 1 236 ? 87.169  100.443 71.681  1.00 23.18  ? 236 LYS B NZ  1 
ATOM   3843  N  N   . THR B 1 237 ? 92.871  96.570  73.215  1.00 28.96  ? 237 THR B N   1 
ATOM   3844  C  CA  . THR B 1 237 ? 92.861  96.564  74.673  1.00 31.34  ? 237 THR B CA  1 
ATOM   3845  C  C   . THR B 1 237 ? 94.135  96.016  75.277  1.00 32.95  ? 237 THR B C   1 
ATOM   3846  O  O   . THR B 1 237 ? 94.344  96.189  76.485  1.00 31.32  ? 237 THR B O   1 
ATOM   3847  C  CB  . THR B 1 237 ? 91.725  95.708  75.212  1.00 27.72  ? 237 THR B CB  1 
ATOM   3848  O  OG1 . THR B 1 237 ? 91.948  94.358  74.796  1.00 28.10  ? 237 THR B OG1 1 
ATOM   3849  C  CG2 . THR B 1 237 ? 90.380  96.197  74.681  1.00 28.88  ? 237 THR B CG2 1 
ATOM   3850  N  N   . GLY B 1 238 ? 94.953  95.328  74.479  1.00 26.38  ? 238 GLY B N   1 
ATOM   3851  C  CA  . GLY B 1 238 ? 96.084  94.609  75.013  1.00 28.39  ? 238 GLY B CA  1 
ATOM   3852  C  C   . GLY B 1 238 ? 95.696  93.394  75.805  1.00 31.30  ? 238 GLY B C   1 
ATOM   3853  O  O   . GLY B 1 238 ? 96.480  92.928  76.627  1.00 29.32  ? 238 GLY B O   1 
ATOM   3854  N  N   . ALA B 1 239 ? 94.501  92.860  75.567  1.00 33.51  ? 239 ALA B N   1 
ATOM   3855  C  CA  . ALA B 1 239 ? 93.963  91.802  76.408  1.00 28.54  ? 239 ALA B CA  1 
ATOM   3856  C  C   . ALA B 1 239 ? 94.876  90.583  76.434  1.00 27.71  ? 239 ALA B C   1 
ATOM   3857  O  O   . ALA B 1 239 ? 95.538  90.246  75.445  1.00 28.39  ? 239 ALA B O   1 
ATOM   3858  C  CB  . ALA B 1 239 ? 92.581  91.380  75.917  1.00 27.77  ? 239 ALA B CB  1 
ATOM   3859  N  N   . LEU B 1 240 ? 94.908  89.929  77.590  1.00 24.76  ? 240 LEU B N   1 
ATOM   3860  C  CA  . LEU B 1 240 ? 95.378  88.556  77.678  1.00 27.07  ? 240 LEU B CA  1 
ATOM   3861  C  C   . LEU B 1 240 ? 94.362  87.641  77.007  1.00 26.93  ? 240 LEU B C   1 
ATOM   3862  O  O   . LEU B 1 240 ? 93.200  87.585  77.427  1.00 27.61  ? 240 LEU B O   1 
ATOM   3863  C  CB  . LEU B 1 240 ? 95.578  88.151  79.141  1.00 26.28  ? 240 LEU B CB  1 
ATOM   3864  C  CG  . LEU B 1 240 ? 95.853  86.650  79.321  1.00 28.60  ? 240 LEU B CG  1 
ATOM   3865  C  CD1 . LEU B 1 240 ? 97.239  86.260  78.744  1.00 28.64  ? 240 LEU B CD1 1 
ATOM   3866  C  CD2 . LEU B 1 240 ? 95.752  86.260  80.765  1.00 27.96  ? 240 LEU B CD2 1 
ATOM   3867  N  N   . VAL B 1 241 ? 94.805  86.913  75.985  1.00 24.80  ? 241 VAL B N   1 
ATOM   3868  C  CA  . VAL B 1 241 ? 93.939  86.105  75.133  1.00 25.04  ? 241 VAL B CA  1 
ATOM   3869  C  C   . VAL B 1 241 ? 93.952  84.664  75.624  1.00 30.38  ? 241 VAL B C   1 
ATOM   3870  O  O   . VAL B 1 241 ? 95.001  84.004  75.606  1.00 31.40  ? 241 VAL B O   1 
ATOM   3871  C  CB  . VAL B 1 241 ? 94.379  86.180  73.664  1.00 26.87  ? 241 VAL B CB  1 
ATOM   3872  C  CG1 . VAL B 1 241 ? 93.496  85.285  72.812  1.00 28.33  ? 241 VAL B CG1 1 
ATOM   3873  C  CG2 . VAL B 1 241 ? 94.328  87.625  73.171  1.00 21.11  ? 241 VAL B CG2 1 
ATOM   3874  N  N   . VAL B 1 242 ? 92.783  84.164  76.030  1.00 23.98  ? 242 VAL B N   1 
ATOM   3875  C  CA  . VAL B 1 242 ? 92.608  82.783  76.472  1.00 29.30  ? 242 VAL B CA  1 
ATOM   3876  C  C   . VAL B 1 242 ? 91.851  82.013  75.397  1.00 34.43  ? 242 VAL B C   1 
ATOM   3877  O  O   . VAL B 1 242 ? 90.681  82.315  75.123  1.00 29.82  ? 242 VAL B O   1 
ATOM   3878  C  CB  . VAL B 1 242 ? 91.849  82.710  77.805  1.00 27.64  ? 242 VAL B CB  1 
ATOM   3879  C  CG1 . VAL B 1 242 ? 91.760  81.284  78.268  1.00 29.83  ? 242 VAL B CG1 1 
ATOM   3880  C  CG2 . VAL B 1 242 ? 92.509  83.598  78.847  1.00 30.93  ? 242 VAL B CG2 1 
ATOM   3881  N  N   . TYR B 1 243 ? 92.498  80.989  74.827  1.00 31.90  ? 243 TYR B N   1 
ATOM   3882  C  CA  . TYR B 1 243 ? 91.873  80.163  73.805  1.00 31.59  ? 243 TYR B CA  1 
ATOM   3883  C  C   . TYR B 1 243 ? 90.984  79.092  74.440  1.00 33.52  ? 243 TYR B C   1 
ATOM   3884  O  O   . TYR B 1 243 ? 91.168  78.692  75.593  1.00 35.35  ? 243 TYR B O   1 
ATOM   3885  C  CB  . TYR B 1 243 ? 92.933  79.523  72.915  1.00 33.85  ? 243 TYR B CB  1 
ATOM   3886  C  CG  . TYR B 1 243 ? 93.974  80.523  72.494  1.00 35.12  ? 243 TYR B CG  1 
ATOM   3887  C  CD1 . TYR B 1 243 ? 93.731  81.402  71.450  1.00 32.15  ? 243 TYR B CD1 1 
ATOM   3888  C  CD2 . TYR B 1 243 ? 95.191  80.613  73.161  1.00 35.71  ? 243 TYR B CD2 1 
ATOM   3889  C  CE1 . TYR B 1 243 ? 94.677  82.336  71.064  1.00 36.37  ? 243 TYR B CE1 1 
ATOM   3890  C  CE2 . TYR B 1 243 ? 96.142  81.552  72.789  1.00 33.39  ? 243 TYR B CE2 1 
ATOM   3891  C  CZ  . TYR B 1 243 ? 95.875  82.408  71.736  1.00 35.05  ? 243 TYR B CZ  1 
ATOM   3892  O  OH  . TYR B 1 243 ? 96.796  83.343  71.330  1.00 39.03  ? 243 TYR B OH  1 
ATOM   3893  N  N   . GLY B 1 244 ? 90.010  78.620  73.659  1.00 30.75  ? 244 GLY B N   1 
ATOM   3894  C  CA  . GLY B 1 244 ? 88.958  77.769  74.179  1.00 34.06  ? 244 GLY B CA  1 
ATOM   3895  C  C   . GLY B 1 244 ? 89.274  76.309  74.466  1.00 33.85  ? 244 GLY B C   1 
ATOM   3896  O  O   . GLY B 1 244 ? 88.779  75.762  75.453  1.00 35.84  ? 244 GLY B O   1 
ATOM   3897  N  N   . HIS B 1 245 ? 90.048  75.651  73.610  1.00 32.74  ? 245 HIS B N   1 
ATOM   3898  C  CA  . HIS B 1 245 ? 90.349  74.228  73.759  1.00 36.47  ? 245 HIS B CA  1 
ATOM   3899  C  C   . HIS B 1 245 ? 91.776  73.974  73.278  1.00 42.31  ? 245 HIS B C   1 
ATOM   3900  O  O   . HIS B 1 245 ? 92.025  73.218  72.338  1.00 42.47  ? 245 HIS B O   1 
ATOM   3901  C  CB  . HIS B 1 245 ? 89.367  73.368  72.966  1.00 36.91  ? 245 HIS B CB  1 
ATOM   3902  C  CG  . HIS B 1 245 ? 87.966  73.369  73.491  1.00 35.62  ? 245 HIS B CG  1 
ATOM   3903  N  ND1 . HIS B 1 245 ? 87.650  72.993  74.779  1.00 39.45  ? 245 HIS B ND1 1 
ATOM   3904  C  CD2 . HIS B 1 245 ? 86.791  73.678  72.888  1.00 36.85  ? 245 HIS B CD2 1 
ATOM   3905  C  CE1 . HIS B 1 245 ? 86.339  73.072  74.949  1.00 39.57  ? 245 HIS B CE1 1 
ATOM   3906  N  NE2 . HIS B 1 245 ? 85.796  73.492  73.819  1.00 35.01  ? 245 HIS B NE2 1 
ATOM   3907  N  N   . ASP B 1 246 ? 92.754  74.630  73.888  1.00 35.21  ? 246 ASP B N   1 
ATOM   3908  C  CA  . ASP B 1 246 ? 94.106  74.530  73.361  1.00 35.96  ? 246 ASP B CA  1 
ATOM   3909  C  C   . ASP B 1 246 ? 94.960  73.727  74.331  1.00 42.05  ? 246 ASP B C   1 
ATOM   3910  O  O   . ASP B 1 246 ? 95.322  74.243  75.402  1.00 39.17  ? 246 ASP B O   1 
ATOM   3911  C  CB  . ASP B 1 246 ? 94.713  75.914  73.121  1.00 35.33  ? 246 ASP B CB  1 
ATOM   3912  C  CG  . ASP B 1 246 ? 96.011  75.841  72.332  1.00 39.49  ? 246 ASP B CG  1 
ATOM   3913  O  OD1 . ASP B 1 246 ? 96.791  74.904  72.588  1.00 39.45  ? 246 ASP B OD1 1 
ATOM   3914  O  OD2 . ASP B 1 246 ? 96.257  76.701  71.447  1.00 40.33  ? 246 ASP B OD2 1 
ATOM   3915  N  N   . PRO B 1 247 ? 95.321  72.485  73.999  1.00 35.15  ? 247 PRO B N   1 
ATOM   3916  C  CA  . PRO B 1 247 ? 96.062  71.657  74.964  1.00 43.43  ? 247 PRO B CA  1 
ATOM   3917  C  C   . PRO B 1 247 ? 97.468  72.162  75.242  1.00 42.23  ? 247 PRO B C   1 
ATOM   3918  O  O   . PRO B 1 247 ? 98.000  71.880  76.322  1.00 47.32  ? 247 PRO B O   1 
ATOM   3919  C  CB  . PRO B 1 247 ? 96.080  70.271  74.299  1.00 43.66  ? 247 PRO B CB  1 
ATOM   3920  C  CG  . PRO B 1 247 ? 95.964  70.560  72.830  1.00 44.45  ? 247 PRO B CG  1 
ATOM   3921  C  CD  . PRO B 1 247 ? 95.068  71.778  72.733  1.00 41.90  ? 247 PRO B CD  1 
ATOM   3922  N  N   . GLU B 1 248 ? 98.076  72.921  74.331  1.00 42.33  ? 248 GLU B N   1 
ATOM   3923  C  CA  . GLU B 1 248 ? 99.421  73.436  74.573  1.00 43.23  ? 248 GLU B CA  1 
ATOM   3924  C  C   . GLU B 1 248 ? 99.422  74.765  75.314  1.00 42.91  ? 248 GLU B C   1 
ATOM   3925  O  O   . GLU B 1 248 ? 100.302 75.007  76.145  1.00 44.66  ? 248 GLU B O   1 
ATOM   3926  C  CB  . GLU B 1 248 ? 100.176 73.597  73.253  1.00 43.08  ? 248 GLU B CB  1 
ATOM   3927  C  CG  . GLU B 1 248 ? 100.866 72.325  72.797  1.00 54.14  ? 248 GLU B CG  1 
ATOM   3928  C  CD  . GLU B 1 248 ? 100.058 71.556  71.777  1.00 59.38  ? 248 GLU B CD  1 
ATOM   3929  O  OE1 . GLU B 1 248 ? 99.854  72.096  70.664  1.00 66.64  ? 248 GLU B OE1 1 
ATOM   3930  O  OE2 . GLU B 1 248 ? 99.634  70.418  72.082  1.00 62.30  ? 248 GLU B OE2 1 
ATOM   3931  N  N   . ALA B 1 249 ? 98.459  75.643  75.029  1.00 41.19  ? 249 ALA B N   1 
ATOM   3932  C  CA  . ALA B 1 249 ? 98.437  76.951  75.676  1.00 43.35  ? 249 ALA B CA  1 
ATOM   3933  C  C   . ALA B 1 249 ? 97.780  76.902  77.054  1.00 42.45  ? 249 ALA B C   1 
ATOM   3934  O  O   . ALA B 1 249 ? 98.190  77.645  77.957  1.00 37.57  ? 249 ALA B O   1 
ATOM   3935  C  CB  . ALA B 1 249 ? 97.712  77.966  74.788  1.00 39.39  ? 249 ALA B CB  1 
ATOM   3936  N  N   . TRP B 1 250 ? 96.777  76.042  77.229  1.00 36.67  ? 250 TRP B N   1 
ATOM   3937  C  CA  . TRP B 1 250 ? 96.025  75.989  78.484  1.00 39.45  ? 250 TRP B CA  1 
ATOM   3938  C  C   . TRP B 1 250 ? 96.925  75.874  79.708  1.00 42.33  ? 250 TRP B C   1 
ATOM   3939  O  O   . TRP B 1 250 ? 96.733  76.660  80.651  1.00 43.18  ? 250 TRP B O   1 
ATOM   3940  C  CB  . TRP B 1 250 ? 95.003  74.841  78.408  1.00 35.53  ? 250 TRP B CB  1 
ATOM   3941  C  CG  . TRP B 1 250 ? 94.081  74.657  79.613  1.00 37.96  ? 250 TRP B CG  1 
ATOM   3942  C  CD1 . TRP B 1 250 ? 93.991  73.549  80.418  1.00 37.95  ? 250 TRP B CD1 1 
ATOM   3943  C  CD2 . TRP B 1 250 ? 93.079  75.571  80.090  1.00 37.92  ? 250 TRP B CD2 1 
ATOM   3944  N  NE1 . TRP B 1 250 ? 93.018  73.729  81.377  1.00 35.69  ? 250 TRP B NE1 1 
ATOM   3945  C  CE2 . TRP B 1 250 ? 92.445  74.962  81.196  1.00 38.71  ? 250 TRP B CE2 1 
ATOM   3946  C  CE3 . TRP B 1 250 ? 92.660  76.847  79.690  1.00 37.03  ? 250 TRP B CE3 1 
ATOM   3947  C  CZ2 . TRP B 1 250 ? 91.423  75.587  81.906  1.00 33.78  ? 250 TRP B CZ2 1 
ATOM   3948  C  CZ3 . TRP B 1 250 ? 91.652  77.467  80.398  1.00 35.70  ? 250 TRP B CZ3 1 
ATOM   3949  C  CH2 . TRP B 1 250 ? 91.045  76.835  81.497  1.00 37.27  ? 250 TRP B CH2 1 
ATOM   3950  N  N   . PRO B 1 251 ? 97.923  74.976  79.758  1.00 41.02  ? 251 PRO B N   1 
ATOM   3951  C  CA  . PRO B 1 251 ? 98.786  74.913  80.952  1.00 41.17  ? 251 PRO B CA  1 
ATOM   3952  C  C   . PRO B 1 251 ? 99.555  76.191  81.225  1.00 41.44  ? 251 PRO B C   1 
ATOM   3953  O  O   . PRO B 1 251 ? 99.985  76.387  82.365  1.00 42.94  ? 251 PRO B O   1 
ATOM   3954  C  CB  . PRO B 1 251 ? 99.747  73.751  80.645  1.00 38.83  ? 251 PRO B CB  1 
ATOM   3955  C  CG  . PRO B 1 251 ? 99.072  72.949  79.632  1.00 46.56  ? 251 PRO B CG  1 
ATOM   3956  C  CD  . PRO B 1 251 ? 98.269  73.912  78.798  1.00 42.14  ? 251 PRO B CD  1 
ATOM   3957  N  N   . THR B 1 252 ? 99.755  77.061  80.232  1.00 39.12  ? 252 THR B N   1 
ATOM   3958  C  CA  . THR B 1 252 ? 100.536 78.266  80.469  1.00 39.48  ? 252 THR B CA  1 
ATOM   3959  C  C   . THR B 1 252 ? 99.754  79.349  81.202  1.00 42.42  ? 252 THR B C   1 
ATOM   3960  O  O   . THR B 1 252 ? 100.358 80.357  81.586  1.00 42.12  ? 252 THR B O   1 
ATOM   3961  C  CB  . THR B 1 252 ? 101.097 78.844  79.153  1.00 41.68  ? 252 THR B CB  1 
ATOM   3962  O  OG1 . THR B 1 252 ? 100.049 79.434  78.369  1.00 44.80  ? 252 THR B OG1 1 
ATOM   3963  C  CG2 . THR B 1 252 ? 101.790 77.763  78.335  1.00 41.26  ? 252 THR B CG2 1 
ATOM   3964  N  N   . PHE B 1 253 ? 98.446  79.175  81.414  1.00 40.81  ? 253 PHE B N   1 
ATOM   3965  C  CA  . PHE B 1 253 ? 97.628  80.145  82.136  1.00 38.78  ? 253 PHE B CA  1 
ATOM   3966  C  C   . PHE B 1 253 ? 97.490  79.733  83.594  1.00 38.28  ? 253 PHE B C   1 
ATOM   3967  O  O   . PHE B 1 253 ? 97.791  78.601  83.977  1.00 39.30  ? 253 PHE B O   1 
ATOM   3968  C  CB  . PHE B 1 253 ? 96.227  80.274  81.525  1.00 35.66  ? 253 PHE B CB  1 
ATOM   3969  C  CG  . PHE B 1 253 ? 96.217  80.639  80.070  1.00 38.95  ? 253 PHE B CG  1 
ATOM   3970  C  CD1 . PHE B 1 253 ? 96.688  81.868  79.643  1.00 39.66  ? 253 PHE B CD1 1 
ATOM   3971  C  CD2 . PHE B 1 253 ? 95.729  79.744  79.128  1.00 34.89  ? 253 PHE B CD2 1 
ATOM   3972  C  CE1 . PHE B 1 253 ? 96.674  82.204  78.298  1.00 38.07  ? 253 PHE B CE1 1 
ATOM   3973  C  CE2 . PHE B 1 253 ? 95.714  80.069  77.790  1.00 38.71  ? 253 PHE B CE2 1 
ATOM   3974  C  CZ  . PHE B 1 253 ? 96.192  81.301  77.367  1.00 37.60  ? 253 PHE B CZ  1 
ATOM   3975  N  N   . ARG B 1 254 ? 96.980  80.657  84.407  1.00 38.42  ? 254 ARG B N   1 
ATOM   3976  C  CA  . ARG B 1 254 ? 96.738  80.353  85.815  1.00 36.09  ? 254 ARG B CA  1 
ATOM   3977  C  C   . ARG B 1 254 ? 95.440  79.570  85.946  1.00 36.20  ? 254 ARG B C   1 
ATOM   3978  O  O   . ARG B 1 254 ? 94.383  80.039  85.513  1.00 36.45  ? 254 ARG B O   1 
ATOM   3979  C  CB  . ARG B 1 254 ? 96.688  81.630  86.648  1.00 40.84  ? 254 ARG B CB  1 
ATOM   3980  C  CG  . ARG B 1 254 ? 97.788  82.636  86.327  1.00 42.24  ? 254 ARG B CG  1 
ATOM   3981  C  CD  . ARG B 1 254 ? 98.149  83.435  87.564  1.00 46.36  ? 254 ARG B CD  1 
ATOM   3982  N  NE  . ARG B 1 254 ? 98.829  84.671  87.212  1.00 48.03  ? 254 ARG B NE  1 
ATOM   3983  C  CZ  . ARG B 1 254 ? 98.638  85.830  87.827  1.00 58.58  ? 254 ARG B CZ  1 
ATOM   3984  N  NH1 . ARG B 1 254 ? 97.792  85.945  88.838  1.00 58.60  ? 254 ARG B NH1 1 
ATOM   3985  N  NH2 . ARG B 1 254 ? 99.313  86.902  87.417  1.00 59.74  ? 254 ARG B NH2 1 
ATOM   3986  N  N   . LEU B 1 255 ? 95.518  78.386  86.542  1.00 30.86  ? 255 LEU B N   1 
ATOM   3987  C  CA  . LEU B 1 255 ? 94.357  77.525  86.669  1.00 35.23  ? 255 LEU B CA  1 
ATOM   3988  C  C   . LEU B 1 255 ? 93.842  77.501  88.100  1.00 35.50  ? 255 LEU B C   1 
ATOM   3989  O  O   . LEU B 1 255 ? 94.613  77.520  89.062  1.00 36.45  ? 255 LEU B O   1 
ATOM   3990  C  CB  . LEU B 1 255 ? 94.690  76.106  86.185  1.00 35.35  ? 255 LEU B CB  1 
ATOM   3991  C  CG  . LEU B 1 255 ? 95.213  76.080  84.741  1.00 41.14  ? 255 LEU B CG  1 
ATOM   3992  C  CD1 . LEU B 1 255 ? 95.302  74.658  84.163  1.00 35.34  ? 255 LEU B CD1 1 
ATOM   3993  C  CD2 . LEU B 1 255 ? 94.386  77.003  83.826  1.00 37.51  ? 255 LEU B CD2 1 
ATOM   3994  N  N   . ARG C 1 5   ? 43.391  95.017  25.760  1.00 28.96  ? 5   ARG C N   1 
ATOM   3995  C  CA  . ARG C 1 5   ? 44.047  96.134  25.066  1.00 29.48  ? 5   ARG C CA  1 
ATOM   3996  C  C   . ARG C 1 5   ? 44.766  97.117  25.983  1.00 29.19  ? 5   ARG C C   1 
ATOM   3997  O  O   . ARG C 1 5   ? 44.292  97.385  27.079  1.00 26.87  ? 5   ARG C O   1 
ATOM   3998  C  CB  . ARG C 1 5   ? 43.028  96.934  24.248  1.00 29.66  ? 5   ARG C CB  1 
ATOM   3999  C  CG  . ARG C 1 5   ? 42.574  96.288  22.950  1.00 31.64  ? 5   ARG C CG  1 
ATOM   4000  C  CD  . ARG C 1 5   ? 41.390  97.065  22.385  1.00 29.65  ? 5   ARG C CD  1 
ATOM   4001  N  NE  . ARG C 1 5   ? 40.884  96.515  21.129  1.00 36.91  ? 5   ARG C NE  1 
ATOM   4002  C  CZ  . ARG C 1 5   ? 40.253  97.227  20.202  1.00 33.07  ? 5   ARG C CZ  1 
ATOM   4003  N  NH1 . ARG C 1 5   ? 40.084  98.533  20.331  1.00 34.47  ? 5   ARG C NH1 1 
ATOM   4004  N  NH2 . ARG C 1 5   ? 39.801  96.617  19.111  1.00 36.81  ? 5   ARG C NH2 1 
ATOM   4005  N  N   . LEU C 1 6   ? 45.866  97.704  25.497  1.00 28.75  ? 6   LEU C N   1 
ATOM   4006  C  CA  . LEU C 1 6   ? 46.541  98.808  26.171  1.00 28.76  ? 6   LEU C CA  1 
ATOM   4007  C  C   . LEU C 1 6   ? 46.325  100.121 25.419  1.00 33.04  ? 6   LEU C C   1 
ATOM   4008  O  O   . LEU C 1 6   ? 46.634  100.214 24.224  1.00 33.39  ? 6   LEU C O   1 
ATOM   4009  C  CB  . LEU C 1 6   ? 48.045  98.543  26.292  1.00 28.97  ? 6   LEU C CB  1 
ATOM   4010  C  CG  . LEU C 1 6   ? 48.869  99.777  26.657  1.00 27.55  ? 6   LEU C CG  1 
ATOM   4011  C  CD1 . LEU C 1 6   ? 48.633  100.182 28.126  1.00 23.08  ? 6   LEU C CD1 1 
ATOM   4012  C  CD2 . LEU C 1 6   ? 50.367  99.555  26.369  1.00 28.32  ? 6   LEU C CD2 1 
ATOM   4013  N  N   . TYR C 1 7   ? 45.850  101.141 26.134  1.00 26.48  ? 7   TYR C N   1 
ATOM   4014  C  CA  . TYR C 1 7   ? 45.722  102.506 25.640  1.00 33.34  ? 7   TYR C CA  1 
ATOM   4015  C  C   . TYR C 1 7   ? 46.629  103.415 26.469  1.00 32.56  ? 7   TYR C C   1 
ATOM   4016  O  O   . TYR C 1 7   ? 46.511  103.464 27.699  1.00 30.94  ? 7   TYR C O   1 
ATOM   4017  C  CB  . TYR C 1 7   ? 44.271  103.023 25.745  1.00 33.20  ? 7   TYR C CB  1 
ATOM   4018  C  CG  . TYR C 1 7   ? 43.234  102.310 24.889  1.00 37.02  ? 7   TYR C CG  1 
ATOM   4019  C  CD1 . TYR C 1 7   ? 42.687  101.092 25.284  1.00 37.31  ? 7   TYR C CD1 1 
ATOM   4020  C  CD2 . TYR C 1 7   ? 42.778  102.876 23.701  1.00 35.43  ? 7   TYR C CD2 1 
ATOM   4021  C  CE1 . TYR C 1 7   ? 41.723  100.450 24.504  1.00 38.71  ? 7   TYR C CE1 1 
ATOM   4022  C  CE2 . TYR C 1 7   ? 41.830  102.252 22.923  1.00 34.52  ? 7   TYR C CE2 1 
ATOM   4023  C  CZ  . TYR C 1 7   ? 41.304  101.042 23.325  1.00 36.22  ? 7   TYR C CZ  1 
ATOM   4024  O  OH  . TYR C 1 7   ? 40.360  100.425 22.546  1.00 34.81  ? 7   TYR C OH  1 
ATOM   4025  N  N   . MET C 1 8   ? 47.504  104.161 25.811  1.00 31.16  ? 8   MET C N   1 
ATOM   4026  C  CA  . MET C 1 8   ? 48.432  105.050 26.504  1.00 32.91  ? 8   MET C CA  1 
ATOM   4027  C  C   . MET C 1 8   ? 47.936  106.486 26.379  1.00 34.89  ? 8   MET C C   1 
ATOM   4028  O  O   . MET C 1 8   ? 47.947  107.057 25.284  1.00 37.26  ? 8   MET C O   1 
ATOM   4029  C  CB  . MET C 1 8   ? 49.851  104.879 25.957  1.00 32.46  ? 8   MET C CB  1 
ATOM   4030  C  CG  . MET C 1 8   ? 50.267  103.407 25.774  1.00 34.52  ? 8   MET C CG  1 
ATOM   4031  S  SD  . MET C 1 8   ? 52.052  103.126 25.819  1.00 38.39  ? 8   MET C SD  1 
ATOM   4032  C  CE  . MET C 1 8   ? 52.546  104.564 24.888  1.00 33.32  ? 8   MET C CE  1 
ATOM   4033  N  N   . PHE C 1 9   ? 47.489  107.054 27.502  1.00 33.07  ? 9   PHE C N   1 
ATOM   4034  C  CA  . PHE C 1 9   ? 47.042  108.434 27.612  1.00 29.92  ? 9   PHE C CA  1 
ATOM   4035  C  C   . PHE C 1 9   ? 48.151  109.305 28.184  1.00 32.70  ? 9   PHE C C   1 
ATOM   4036  O  O   . PHE C 1 9   ? 49.247  108.836 28.514  1.00 32.35  ? 9   PHE C O   1 
ATOM   4037  C  CB  . PHE C 1 9   ? 45.820  108.549 28.519  1.00 28.36  ? 9   PHE C CB  1 
ATOM   4038  C  CG  . PHE C 1 9   ? 44.584  107.927 27.961  1.00 32.21  ? 9   PHE C CG  1 
ATOM   4039  C  CD1 . PHE C 1 9   ? 43.711  108.671 27.174  1.00 34.27  ? 9   PHE C CD1 1 
ATOM   4040  C  CD2 . PHE C 1 9   ? 44.276  106.601 28.238  1.00 29.25  ? 9   PHE C CD2 1 
ATOM   4041  C  CE1 . PHE C 1 9   ? 42.548  108.099 26.670  1.00 34.40  ? 9   PHE C CE1 1 
ATOM   4042  C  CE2 . PHE C 1 9   ? 43.131  106.019 27.728  1.00 30.21  ? 9   PHE C CE2 1 
ATOM   4043  C  CZ  . PHE C 1 9   ? 42.259  106.770 26.948  1.00 35.46  ? 9   PHE C CZ  1 
ATOM   4044  N  N   . GLN C 1 10  ? 47.840  110.593 28.345  1.00 32.40  ? 10  GLN C N   1 
ATOM   4045  C  CA  . GLN C 1 10  ? 48.734  111.514 29.029  1.00 31.78  ? 10  GLN C CA  1 
ATOM   4046  C  C   . GLN C 1 10  ? 47.903  112.649 29.593  1.00 31.29  ? 10  GLN C C   1 
ATOM   4047  O  O   . GLN C 1 10  ? 46.892  113.038 29.003  1.00 34.08  ? 10  GLN C O   1 
ATOM   4048  C  CB  . GLN C 1 10  ? 49.840  112.044 28.096  1.00 32.37  ? 10  GLN C CB  1 
ATOM   4049  C  CG  . GLN C 1 10  ? 49.474  113.285 27.281  1.00 29.74  ? 10  GLN C CG  1 
ATOM   4050  C  CD  . GLN C 1 10  ? 50.585  113.699 26.317  1.00 36.61  ? 10  GLN C CD  1 
ATOM   4051  O  OE1 . GLN C 1 10  ? 50.802  113.050 25.289  1.00 33.51  ? 10  GLN C OE1 1 
ATOM   4052  N  NE2 . GLN C 1 10  ? 51.294  114.782 26.649  1.00 33.79  ? 10  GLN C NE2 1 
ATOM   4053  N  N   . THR C 1 11  ? 48.308  113.150 30.761  1.00 30.18  ? 11  THR C N   1 
ATOM   4054  C  CA  . THR C 1 11  ? 47.685  114.354 31.318  1.00 36.29  ? 11  THR C CA  1 
ATOM   4055  C  C   . THR C 1 11  ? 48.608  115.549 31.072  1.00 34.85  ? 11  THR C C   1 
ATOM   4056  O  O   . THR C 1 11  ? 49.293  116.060 31.958  1.00 38.76  ? 11  THR C O   1 
ATOM   4057  C  CB  . THR C 1 11  ? 47.357  114.179 32.807  1.00 32.42  ? 11  THR C CB  1 
ATOM   4058  O  OG1 . THR C 1 11  ? 48.555  113.957 33.557  1.00 33.49  ? 11  THR C OG1 1 
ATOM   4059  C  CG2 . THR C 1 11  ? 46.426  113.017 33.021  1.00 29.96  ? 11  THR C CG2 1 
ATOM   4060  N  N   . GLY C 1 12  ? 48.615  115.984 29.818  1.00 35.57  ? 12  GLY C N   1 
ATOM   4061  C  CA  . GLY C 1 12  ? 49.377  117.168 29.465  1.00 36.77  ? 12  GLY C CA  1 
ATOM   4062  C  C   . GLY C 1 12  ? 50.870  116.954 29.617  1.00 40.16  ? 12  GLY C C   1 
ATOM   4063  O  O   . GLY C 1 12  ? 51.435  115.930 29.197  1.00 37.09  ? 12  GLY C O   1 
ATOM   4064  N  N   . THR C 1 13  ? 51.522  117.939 30.232  1.00 36.97  ? 13  THR C N   1 
ATOM   4065  C  CA  . THR C 1 13  ? 52.970  117.956 30.344  1.00 39.82  ? 13  THR C CA  1 
ATOM   4066  C  C   . THR C 1 13  ? 53.371  118.565 31.676  1.00 38.03  ? 13  THR C C   1 
ATOM   4067  O  O   . THR C 1 13  ? 52.553  119.136 32.403  1.00 40.23  ? 13  THR C O   1 
ATOM   4068  C  CB  . THR C 1 13  ? 53.631  118.740 29.194  1.00 38.58  ? 13  THR C CB  1 
ATOM   4069  O  OG1 . THR C 1 13  ? 53.006  120.021 29.069  1.00 42.18  ? 13  THR C OG1 1 
ATOM   4070  C  CG2 . THR C 1 13  ? 53.531  117.983 27.871  1.00 37.39  ? 13  THR C CG2 1 
ATOM   4071  N  N   . LEU C 1 14  ? 54.653  118.426 31.993  1.00 39.38  ? 14  LEU C N   1 
ATOM   4072  C  CA  . LEU C 1 14  ? 55.279  119.120 33.109  1.00 40.05  ? 14  LEU C CA  1 
ATOM   4073  C  C   . LEU C 1 14  ? 56.403  119.989 32.563  1.00 41.79  ? 14  LEU C C   1 
ATOM   4074  O  O   . LEU C 1 14  ? 57.166  119.552 31.692  1.00 40.66  ? 14  LEU C O   1 
ATOM   4075  C  CB  . LEU C 1 14  ? 55.854  118.134 34.143  1.00 37.94  ? 14  LEU C CB  1 
ATOM   4076  C  CG  . LEU C 1 14  ? 54.924  117.269 34.988  1.00 36.74  ? 14  LEU C CG  1 
ATOM   4077  C  CD1 . LEU C 1 14  ? 55.743  116.466 35.979  1.00 35.16  ? 14  LEU C CD1 1 
ATOM   4078  C  CD2 . LEU C 1 14  ? 53.880  118.108 35.713  1.00 34.30  ? 14  LEU C CD2 1 
ATOM   4079  N  N   . LYS C 1 15  ? 56.510  121.212 33.078  1.00 43.00  ? 15  LYS C N   1 
ATOM   4080  C  CA  . LYS C 1 15  ? 57.624  122.103 32.763  1.00 47.41  ? 15  LYS C CA  1 
ATOM   4081  C  C   . LYS C 1 15  ? 58.592  122.124 33.944  1.00 43.46  ? 15  LYS C C   1 
ATOM   4082  O  O   . LYS C 1 15  ? 58.199  122.452 35.070  1.00 39.02  ? 15  LYS C O   1 
ATOM   4083  C  CB  . LYS C 1 15  ? 57.134  123.518 32.443  1.00 48.99  ? 15  LYS C CB  1 
ATOM   4084  C  CG  . LYS C 1 15  ? 56.245  123.635 31.206  1.00 52.15  ? 15  LYS C CG  1 
ATOM   4085  C  CD  . LYS C 1 15  ? 55.721  125.063 31.026  1.00 62.45  ? 15  LYS C CD  1 
ATOM   4086  C  CE  . LYS C 1 15  ? 56.669  125.911 30.200  1.00 69.46  ? 15  LYS C CE  1 
ATOM   4087  N  NZ  . LYS C 1 15  ? 56.714  125.425 28.793  1.00 71.80  ? 15  LYS C NZ  1 
ATOM   4088  N  N   . CYS C 1 16  ? 59.847  121.781 33.678  1.00 40.08  ? 16  CYS C N   1 
ATOM   4089  C  CA  . CYS C 1 16  ? 60.895  121.740 34.694  1.00 48.46  ? 16  CYS C CA  1 
ATOM   4090  C  C   . CYS C 1 16  ? 62.203  122.155 34.020  1.00 49.62  ? 16  CYS C C   1 
ATOM   4091  O  O   . CYS C 1 16  ? 62.208  122.754 32.940  1.00 52.91  ? 16  CYS C O   1 
ATOM   4092  C  CB  . CYS C 1 16  ? 60.956  120.340 35.326  1.00 46.25  ? 16  CYS C CB  1 
ATOM   4093  S  SG  . CYS C 1 16  ? 61.073  119.002 34.095  1.00 43.98  ? 16  CYS C SG  1 
ATOM   4094  N  N   . ARG C 1 17  ? 63.335  121.845 34.645  1.00 50.87  ? 17  ARG C N   1 
ATOM   4095  C  CA  . ARG C 1 17  ? 64.635  121.975 33.996  1.00 52.03  ? 17  ARG C CA  1 
ATOM   4096  C  C   . ARG C 1 17  ? 65.167  120.594 33.640  1.00 51.97  ? 17  ARG C C   1 
ATOM   4097  O  O   . ARG C 1 17  ? 64.736  119.578 34.194  1.00 54.47  ? 17  ARG C O   1 
ATOM   4098  C  CB  . ARG C 1 17  ? 65.647  122.698 34.886  1.00 51.16  ? 17  ARG C CB  1 
ATOM   4099  C  CG  . ARG C 1 17  ? 65.134  123.972 35.510  1.00 52.54  ? 17  ARG C CG  1 
ATOM   4100  C  CD  . ARG C 1 17  ? 65.991  124.347 36.711  1.00 59.01  ? 17  ARG C CD  1 
ATOM   4101  N  NE  . ARG C 1 17  ? 65.633  125.657 37.243  1.00 65.35  ? 17  ARG C NE  1 
ATOM   4102  C  CZ  . ARG C 1 17  ? 66.024  126.809 36.715  1.00 70.73  ? 17  ARG C CZ  1 
ATOM   4103  N  NH1 . ARG C 1 17  ? 66.823  126.849 35.657  1.00 69.81  ? 17  ARG C NH1 1 
ATOM   4104  N  NH2 . ARG C 1 17  ? 65.607  127.948 37.261  1.00 70.14  ? 17  ARG C NH2 1 
ATOM   4105  N  N   . VAL C 1 18  ? 66.114  120.565 32.701  1.00 50.28  ? 18  VAL C N   1 
ATOM   4106  C  CA  . VAL C 1 18  ? 66.698  119.300 32.260  1.00 49.40  ? 18  VAL C CA  1 
ATOM   4107  C  C   . VAL C 1 18  ? 67.230  118.496 33.445  1.00 48.68  ? 18  VAL C C   1 
ATOM   4108  O  O   . VAL C 1 18  ? 67.115  117.266 33.472  1.00 46.58  ? 18  VAL C O   1 
ATOM   4109  C  CB  . VAL C 1 18  ? 67.807  119.575 31.212  1.00 53.99  ? 18  VAL C CB  1 
ATOM   4110  C  CG1 . VAL C 1 18  ? 68.866  118.477 31.234  1.00 54.75  ? 18  VAL C CG1 1 
ATOM   4111  C  CG2 . VAL C 1 18  ? 67.208  119.731 29.815  1.00 51.20  ? 18  VAL C CG2 1 
ATOM   4112  N  N   . CYS C 1 19  ? 67.785  119.174 34.457  1.00 47.33  ? 19  CYS C N   1 
ATOM   4113  C  CA  . CYS C 1 19  ? 68.472  118.479 35.539  1.00 45.93  ? 19  CYS C CA  1 
ATOM   4114  C  C   . CYS C 1 19  ? 67.518  117.725 36.454  1.00 46.74  ? 19  CYS C C   1 
ATOM   4115  O  O   . CYS C 1 19  ? 67.957  116.801 37.150  1.00 44.70  ? 19  CYS C O   1 
ATOM   4116  C  CB  . CYS C 1 19  ? 69.288  119.470 36.365  1.00 42.69  ? 19  CYS C CB  1 
ATOM   4117  S  SG  . CYS C 1 19  ? 68.266  120.751 37.092  1.00 43.41  ? 19  CYS C SG  1 
ATOM   4118  N  N   . ASN C 1 20  ? 66.239  118.110 36.500  1.00 41.89  ? 20  ASN C N   1 
ATOM   4119  C  CA  . ASN C 1 20  ? 65.284  117.323 37.272  1.00 45.00  ? 20  ASN C CA  1 
ATOM   4120  C  C   . ASN C 1 20  ? 65.026  115.959 36.651  1.00 46.79  ? 20  ASN C C   1 
ATOM   4121  O  O   . ASN C 1 20  ? 64.538  115.060 37.350  1.00 45.18  ? 20  ASN C O   1 
ATOM   4122  C  CB  . ASN C 1 20  ? 63.948  118.050 37.420  1.00 45.36  ? 20  ASN C CB  1 
ATOM   4123  C  CG  . ASN C 1 20  ? 64.094  119.463 37.940  1.00 47.03  ? 20  ASN C CG  1 
ATOM   4124  O  OD1 . ASN C 1 20  ? 63.901  120.426 37.195  1.00 48.58  ? 20  ASN C OD1 1 
ATOM   4125  N  ND2 . ASN C 1 20  ? 64.410  119.599 39.229  1.00 39.80  ? 20  ASN C ND2 1 
ATOM   4126  N  N   . ILE C 1 21  ? 65.332  115.789 35.366  1.00 46.50  ? 21  ILE C N   1 
ATOM   4127  C  CA  . ILE C 1 21  ? 65.174  114.511 34.670  1.00 47.07  ? 21  ILE C CA  1 
ATOM   4128  C  C   . ILE C 1 21  ? 66.510  113.787 34.509  1.00 46.07  ? 21  ILE C C   1 
ATOM   4129  O  O   . ILE C 1 21  ? 66.626  112.602 34.821  1.00 42.38  ? 21  ILE C O   1 
ATOM   4130  C  CB  . ILE C 1 21  ? 64.487  114.729 33.303  1.00 47.28  ? 21  ILE C CB  1 
ATOM   4131  C  CG1 . ILE C 1 21  ? 63.338  115.734 33.434  1.00 48.50  ? 21  ILE C CG1 1 
ATOM   4132  C  CG2 . ILE C 1 21  ? 63.971  113.412 32.762  1.00 42.88  ? 21  ILE C CG2 1 
ATOM   4133  C  CD1 . ILE C 1 21  ? 62.217  115.276 34.333  1.00 46.98  ? 21  ILE C CD1 1 
ATOM   4134  N  N   . LYS C 1 22  ? 67.527  114.481 34.011  1.00 45.73  ? 22  LYS C N   1 
ATOM   4135  C  CA  . LYS C 1 22  ? 68.870  113.928 33.857  1.00 47.00  ? 22  LYS C CA  1 
ATOM   4136  C  C   . LYS C 1 22  ? 69.764  114.655 34.863  1.00 49.33  ? 22  LYS C C   1 
ATOM   4137  O  O   . LYS C 1 22  ? 70.111  115.822 34.661  1.00 50.88  ? 22  LYS C O   1 
ATOM   4138  C  CB  . LYS C 1 22  ? 69.353  114.084 32.415  1.00 49.74  ? 22  LYS C CB  1 
ATOM   4139  C  CG  . LYS C 1 22  ? 68.399  113.453 31.406  1.00 51.38  ? 22  LYS C CG  1 
ATOM   4140  C  CD  . LYS C 1 22  ? 68.915  113.505 29.976  1.00 55.72  ? 22  LYS C CD  1 
ATOM   4141  C  CE  . LYS C 1 22  ? 67.824  113.018 29.016  1.00 60.84  ? 22  LYS C CE  1 
ATOM   4142  N  NZ  . LYS C 1 22  ? 68.246  112.887 27.590  1.00 58.29  ? 22  LYS C NZ  1 
ATOM   4143  N  N   . MET C 1 23  ? 70.107  113.972 35.959  1.00 44.86  ? 23  MET C N   1 
ATOM   4144  C  CA  . MET C 1 23  ? 70.776  114.622 37.086  1.00 51.01  ? 23  MET C CA  1 
ATOM   4145  C  C   . MET C 1 23  ? 72.060  115.318 36.637  1.00 53.27  ? 23  MET C C   1 
ATOM   4146  O  O   . MET C 1 23  ? 72.862  114.745 35.889  1.00 47.18  ? 23  MET C O   1 
ATOM   4147  C  CB  . MET C 1 23  ? 71.095  113.598 38.182  1.00 42.92  ? 23  MET C CB  1 
ATOM   4148  C  CG  . MET C 1 23  ? 71.771  114.202 39.407  1.00 45.84  ? 23  MET C CG  1 
ATOM   4149  S  SD  . MET C 1 23  ? 72.419  112.990 40.590  1.00 54.42  ? 23  MET C SD  1 
ATOM   4150  C  CE  . MET C 1 23  ? 73.892  112.431 39.731  1.00 46.74  ? 23  MET C CE  1 
ATOM   4151  N  N   . ASN C 1 24  ? 72.238  116.567 37.095  1.00 50.62  ? 24  ASN C N   1 
ATOM   4152  C  CA  . ASN C 1 24  ? 73.469  117.341 36.890  1.00 52.34  ? 24  ASN C CA  1 
ATOM   4153  C  C   . ASN C 1 24  ? 73.738  117.634 35.416  1.00 47.71  ? 24  ASN C C   1 
ATOM   4154  O  O   . ASN C 1 24  ? 74.897  117.737 35.004  1.00 52.87  ? 24  ASN C O   1 
ATOM   4155  C  CB  . ASN C 1 24  ? 74.692  116.635 37.499  1.00 50.45  ? 24  ASN C CB  1 
ATOM   4156  C  CG  . ASN C 1 24  ? 74.616  116.511 39.011  1.00 47.83  ? 24  ASN C CG  1 
ATOM   4157  O  OD1 . ASN C 1 24  ? 74.016  117.343 39.684  1.00 47.42  ? 24  ASN C OD1 1 
ATOM   4158  N  ND2 . ASN C 1 24  ? 75.240  115.466 39.550  1.00 48.34  ? 24  ASN C ND2 1 
ATOM   4159  N  N   . ALA C 1 25  ? 72.691  117.786 34.606  1.00 43.71  ? 25  ALA C N   1 
ATOM   4160  C  CA  . ALA C 1 25  ? 72.863  117.945 33.163  1.00 54.62  ? 25  ALA C CA  1 
ATOM   4161  C  C   . ALA C 1 25  ? 72.583  119.356 32.659  1.00 53.47  ? 25  ALA C C   1 
ATOM   4162  O  O   . ALA C 1 25  ? 72.702  119.597 31.452  1.00 54.57  ? 25  ALA C O   1 
ATOM   4163  C  CB  . ALA C 1 25  ? 71.978  116.951 32.398  1.00 47.20  ? 25  ALA C CB  1 
ATOM   4164  N  N   . GLY C 1 26  ? 72.216  120.290 33.532  1.00 50.38  ? 26  GLY C N   1 
ATOM   4165  C  CA  . GLY C 1 26  ? 71.964  121.651 33.096  1.00 52.10  ? 26  GLY C CA  1 
ATOM   4166  C  C   . GLY C 1 26  ? 70.667  122.239 33.615  1.00 56.41  ? 26  GLY C C   1 
ATOM   4167  O  O   . GLY C 1 26  ? 69.764  121.507 34.030  1.00 53.10  ? 26  GLY C O   1 
ATOM   4168  N  N   . LEU C 1 27  ? 70.558  123.565 33.583  1.00 53.98  ? 27  LEU C N   1 
ATOM   4169  C  CA  . LEU C 1 27  ? 69.388  124.265 34.094  1.00 57.12  ? 27  LEU C CA  1 
ATOM   4170  C  C   . LEU C 1 27  ? 68.436  124.707 32.988  1.00 58.04  ? 27  LEU C C   1 
ATOM   4171  O  O   . LEU C 1 27  ? 67.444  125.388 33.273  1.00 56.36  ? 27  LEU C O   1 
ATOM   4172  C  CB  . LEU C 1 27  ? 69.829  125.464 34.941  1.00 53.40  ? 27  LEU C CB  1 
ATOM   4173  C  CG  . LEU C 1 27  ? 70.966  125.124 35.906  1.00 55.73  ? 27  LEU C CG  1 
ATOM   4174  C  CD1 . LEU C 1 27  ? 71.365  126.326 36.729  1.00 53.31  ? 27  LEU C CD1 1 
ATOM   4175  C  CD2 . LEU C 1 27  ? 70.538  123.972 36.816  1.00 53.78  ? 27  LEU C CD2 1 
ATOM   4176  N  N   . ASP C 1 28  ? 68.703  124.321 31.742  1.00 56.86  ? 28  ASP C N   1 
ATOM   4177  C  CA  . ASP C 1 28  ? 67.840  124.712 30.635  1.00 61.05  ? 28  ASP C CA  1 
ATOM   4178  C  C   . ASP C 1 28  ? 66.413  124.212 30.855  1.00 63.57  ? 28  ASP C C   1 
ATOM   4179  O  O   . ASP C 1 28  ? 66.188  123.140 31.425  1.00 62.72  ? 28  ASP C O   1 
ATOM   4180  C  CB  . ASP C 1 28  ? 68.382  124.158 29.319  1.00 61.55  ? 28  ASP C CB  1 
ATOM   4181  C  CG  . ASP C 1 28  ? 69.478  125.010 28.736  1.00 68.78  ? 28  ASP C CG  1 
ATOM   4182  O  OD1 . ASP C 1 28  ? 69.496  126.231 29.009  1.00 74.25  ? 28  ASP C OD1 1 
ATOM   4183  O  OD2 . ASP C 1 28  ? 70.317  124.457 27.993  1.00 68.72  ? 28  ASP C OD2 1 
ATOM   4184  N  N   . ASP C 1 29  ? 65.443  125.007 30.401  1.00 62.69  ? 29  ASP C N   1 
ATOM   4185  C  CA  . ASP C 1 29  ? 64.046  124.608 30.495  1.00 59.46  ? 29  ASP C CA  1 
ATOM   4186  C  C   . ASP C 1 29  ? 63.804  123.315 29.726  1.00 59.90  ? 29  ASP C C   1 
ATOM   4187  O  O   . ASP C 1 29  ? 64.439  123.043 28.701  1.00 59.30  ? 29  ASP C O   1 
ATOM   4188  C  CB  . ASP C 1 29  ? 63.132  125.711 29.968  1.00 62.76  ? 29  ASP C CB  1 
ATOM   4189  C  CG  . ASP C 1 29  ? 62.684  126.664 31.058  1.00 68.83  ? 29  ASP C CG  1 
ATOM   4190  O  OD1 . ASP C 1 29  ? 61.838  126.267 31.893  1.00 69.41  ? 29  ASP C OD1 1 
ATOM   4191  O  OD2 . ASP C 1 29  ? 63.167  127.814 31.078  1.00 73.36  ? 29  ASP C OD2 1 
ATOM   4192  N  N   . TYR C 1 30  ? 62.877  122.509 30.244  1.00 53.60  ? 30  TYR C N   1 
ATOM   4193  C  CA  . TYR C 1 30  ? 62.613  121.167 29.738  1.00 54.39  ? 30  TYR C CA  1 
ATOM   4194  C  C   . TYR C 1 30  ? 61.138  120.870 29.942  1.00 47.69  ? 30  TYR C C   1 
ATOM   4195  O  O   . TYR C 1 30  ? 60.530  121.337 30.911  1.00 48.15  ? 30  TYR C O   1 
ATOM   4196  C  CB  . TYR C 1 30  ? 63.486  120.117 30.455  1.00 53.15  ? 30  TYR C CB  1 
ATOM   4197  C  CG  . TYR C 1 30  ? 63.654  118.769 29.757  1.00 49.68  ? 30  TYR C CG  1 
ATOM   4198  C  CD1 . TYR C 1 30  ? 64.237  118.679 28.500  1.00 47.28  ? 30  TYR C CD1 1 
ATOM   4199  C  CD2 . TYR C 1 30  ? 63.282  117.581 30.392  1.00 46.72  ? 30  TYR C CD2 1 
ATOM   4200  C  CE1 . TYR C 1 30  ? 64.420  117.453 27.876  1.00 50.31  ? 30  TYR C CE1 1 
ATOM   4201  C  CE2 . TYR C 1 30  ? 63.462  116.345 29.779  1.00 44.02  ? 30  TYR C CE2 1 
ATOM   4202  C  CZ  . TYR C 1 30  ? 64.032  116.289 28.520  1.00 54.35  ? 30  TYR C CZ  1 
ATOM   4203  O  OH  . TYR C 1 30  ? 64.224  115.072 27.896  1.00 53.37  ? 30  TYR C OH  1 
ATOM   4204  N  N   . GLU C 1 31  ? 60.561  120.106 29.016  1.00 46.81  ? 31  GLU C N   1 
ATOM   4205  C  CA  . GLU C 1 31  ? 59.141  119.777 29.072  1.00 46.18  ? 31  GLU C CA  1 
ATOM   4206  C  C   . GLU C 1 31  ? 58.964  118.287 28.833  1.00 41.69  ? 31  GLU C C   1 
ATOM   4207  O  O   . GLU C 1 31  ? 59.578  117.727 27.921  1.00 43.49  ? 31  GLU C O   1 
ATOM   4208  C  CB  . GLU C 1 31  ? 58.346  120.584 28.047  1.00 44.02  ? 31  GLU C CB  1 
ATOM   4209  C  CG  . GLU C 1 31  ? 56.860  120.456 28.205  1.00 43.73  ? 31  GLU C CG  1 
ATOM   4210  C  CD  . GLU C 1 31  ? 56.104  121.561 27.500  1.00 50.36  ? 31  GLU C CD  1 
ATOM   4211  O  OE1 . GLU C 1 31  ? 56.737  122.353 26.768  1.00 55.68  ? 31  GLU C OE1 1 
ATOM   4212  O  OE2 . GLU C 1 31  ? 54.872  121.636 27.676  1.00 45.52  ? 31  GLU C OE2 1 
ATOM   4213  N  N   . ILE C 1 32  ? 58.140  117.642 29.653  1.00 42.54  ? 32  ILE C N   1 
ATOM   4214  C  CA  . ILE C 1 32  ? 57.993  116.189 29.542  1.00 36.72  ? 32  ILE C CA  1 
ATOM   4215  C  C   . ILE C 1 32  ? 56.521  115.793 29.502  1.00 31.92  ? 32  ILE C C   1 
ATOM   4216  O  O   . ILE C 1 32  ? 55.684  116.437 30.151  1.00 30.49  ? 32  ILE C O   1 
ATOM   4217  C  CB  . ILE C 1 32  ? 58.733  115.470 30.683  1.00 34.62  ? 32  ILE C CB  1 
ATOM   4218  C  CG1 . ILE C 1 32  ? 58.338  116.032 32.043  1.00 36.49  ? 32  ILE C CG1 1 
ATOM   4219  C  CG2 . ILE C 1 32  ? 60.236  115.567 30.516  1.00 38.56  ? 32  ILE C CG2 1 
ATOM   4220  C  CD1 . ILE C 1 32  ? 58.477  115.004 33.133  1.00 39.20  ? 32  ILE C CD1 1 
ATOM   4221  N  N   . PRO C 1 33  ? 56.160  114.757 28.750  1.00 32.07  ? 33  PRO C N   1 
ATOM   4222  C  CA  . PRO C 1 33  ? 54.792  114.238 28.823  1.00 34.25  ? 33  PRO C CA  1 
ATOM   4223  C  C   . PRO C 1 33  ? 54.568  113.548 30.166  1.00 37.09  ? 33  PRO C C   1 
ATOM   4224  O  O   . PRO C 1 33  ? 55.517  113.127 30.834  1.00 33.31  ? 33  PRO C O   1 
ATOM   4225  C  CB  . PRO C 1 33  ? 54.731  113.244 27.656  1.00 31.34  ? 33  PRO C CB  1 
ATOM   4226  C  CG  . PRO C 1 33  ? 56.142  112.713 27.562  1.00 31.54  ? 33  PRO C CG  1 
ATOM   4227  C  CD  . PRO C 1 33  ? 57.049  113.874 27.965  1.00 31.40  ? 33  PRO C CD  1 
ATOM   4228  N  N   . VAL C 1 34  ? 53.299  113.471 30.576  1.00 34.74  ? 34  VAL C N   1 
ATOM   4229  C  CA  . VAL C 1 34  ? 52.911  112.731 31.784  1.00 32.96  ? 34  VAL C CA  1 
ATOM   4230  C  C   . VAL C 1 34  ? 52.022  111.558 31.387  1.00 31.18  ? 34  VAL C C   1 
ATOM   4231  O  O   . VAL C 1 34  ? 50.794  111.688 31.333  1.00 29.64  ? 34  VAL C O   1 
ATOM   4232  C  CB  . VAL C 1 34  ? 52.189  113.620 32.809  1.00 33.11  ? 34  VAL C CB  1 
ATOM   4233  C  CG1 . VAL C 1 34  ? 51.705  112.770 34.007  1.00 30.16  ? 34  VAL C CG1 1 
ATOM   4234  C  CG2 . VAL C 1 34  ? 53.095  114.743 33.282  1.00 33.32  ? 34  VAL C CG2 1 
ATOM   4235  N  N   . PRO C 1 35  ? 52.585  110.405 31.085  1.00 29.33  ? 35  PRO C N   1 
ATOM   4236  C  CA  . PRO C 1 35  ? 51.754  109.296 30.620  1.00 31.88  ? 35  PRO C CA  1 
ATOM   4237  C  C   . PRO C 1 35  ? 50.866  108.743 31.727  1.00 32.96  ? 35  PRO C C   1 
ATOM   4238  O  O   . PRO C 1 35  ? 51.100  108.943 32.928  1.00 27.94  ? 35  PRO C O   1 
ATOM   4239  C  CB  . PRO C 1 35  ? 52.778  108.256 30.161  1.00 28.17  ? 35  PRO C CB  1 
ATOM   4240  C  CG  . PRO C 1 35  ? 54.019  109.052 29.895  1.00 32.90  ? 35  PRO C CG  1 
ATOM   4241  C  CD  . PRO C 1 35  ? 54.013  110.102 30.973  1.00 33.35  ? 35  PRO C CD  1 
ATOM   4242  N  N   . TRP C 1 36  ? 49.816  108.051 31.290  1.00 29.15  ? 36  TRP C N   1 
ATOM   4243  C  CA  . TRP C 1 36  ? 49.073  107.139 32.153  1.00 28.80  ? 36  TRP C CA  1 
ATOM   4244  C  C   . TRP C 1 36  ? 48.363  106.133 31.256  1.00 29.86  ? 36  TRP C C   1 
ATOM   4245  O  O   . TRP C 1 36  ? 48.247  106.334 30.043  1.00 29.93  ? 36  TRP C O   1 
ATOM   4246  C  CB  . TRP C 1 36  ? 48.120  107.885 33.096  1.00 26.94  ? 36  TRP C CB  1 
ATOM   4247  C  CG  . TRP C 1 36  ? 46.942  108.530 32.462  1.00 30.78  ? 36  TRP C CG  1 
ATOM   4248  C  CD1 . TRP C 1 36  ? 46.864  109.804 31.977  1.00 31.22  ? 36  TRP C CD1 1 
ATOM   4249  C  CD2 . TRP C 1 36  ? 45.646  107.944 32.268  1.00 32.08  ? 36  TRP C CD2 1 
ATOM   4250  N  NE1 . TRP C 1 36  ? 45.599  110.046 31.488  1.00 31.16  ? 36  TRP C NE1 1 
ATOM   4251  C  CE2 . TRP C 1 36  ? 44.839  108.916 31.641  1.00 32.40  ? 36  TRP C CE2 1 
ATOM   4252  C  CE3 . TRP C 1 36  ? 45.097  106.683 32.544  1.00 29.42  ? 36  TRP C CE3 1 
ATOM   4253  C  CZ2 . TRP C 1 36  ? 43.510  108.666 31.286  1.00 34.07  ? 36  TRP C CZ2 1 
ATOM   4254  C  CZ3 . TRP C 1 36  ? 43.782  106.437 32.198  1.00 27.68  ? 36  TRP C CZ3 1 
ATOM   4255  C  CH2 . TRP C 1 36  ? 42.999  107.427 31.582  1.00 34.13  ? 36  TRP C CH2 1 
ATOM   4256  N  N   . TYR C 1 37  ? 47.939  105.018 31.850  1.00 27.94  ? 37  TYR C N   1 
ATOM   4257  C  CA  . TYR C 1 37  ? 47.595  103.848 31.052  1.00 25.04  ? 37  TYR C CA  1 
ATOM   4258  C  C   . TYR C 1 37  ? 46.231  103.297 31.426  1.00 26.24  ? 37  TYR C C   1 
ATOM   4259  O  O   . TYR C 1 37  ? 45.801  103.372 32.579  1.00 24.99  ? 37  TYR C O   1 
ATOM   4260  C  CB  . TYR C 1 37  ? 48.659  102.758 31.181  1.00 24.70  ? 37  TYR C CB  1 
ATOM   4261  C  CG  . TYR C 1 37  ? 50.059  103.307 30.981  1.00 25.92  ? 37  TYR C CG  1 
ATOM   4262  C  CD1 . TYR C 1 37  ? 50.620  103.425 29.718  1.00 24.27  ? 37  TYR C CD1 1 
ATOM   4263  C  CD2 . TYR C 1 37  ? 50.811  103.720 32.071  1.00 27.75  ? 37  TYR C CD2 1 
ATOM   4264  C  CE1 . TYR C 1 37  ? 51.920  103.959 29.557  1.00 29.56  ? 37  TYR C CE1 1 
ATOM   4265  C  CE2 . TYR C 1 37  ? 52.092  104.227 31.925  1.00 27.18  ? 37  TYR C CE2 1 
ATOM   4266  C  CZ  . TYR C 1 37  ? 52.646  104.352 30.684  1.00 26.51  ? 37  TYR C CZ  1 
ATOM   4267  O  OH  . TYR C 1 37  ? 53.929  104.868 30.606  1.00 29.90  ? 37  TYR C OH  1 
ATOM   4268  N  N   . LEU C 1 38  ? 45.544  102.779 30.413  1.00 24.08  ? 38  LEU C N   1 
ATOM   4269  C  CA  . LEU C 1 38  ? 44.273  102.091 30.565  1.00 25.67  ? 38  LEU C CA  1 
ATOM   4270  C  C   . LEU C 1 38  ? 44.439  100.703 29.983  1.00 28.87  ? 38  LEU C C   1 
ATOM   4271  O  O   . LEU C 1 38  ? 44.905  100.560 28.845  1.00 24.48  ? 38  LEU C O   1 
ATOM   4272  C  CB  . LEU C 1 38  ? 43.140  102.815 29.830  1.00 26.84  ? 38  LEU C CB  1 
ATOM   4273  C  CG  . LEU C 1 38  ? 41.832  102.042 29.613  1.00 29.24  ? 38  LEU C CG  1 
ATOM   4274  C  CD1 . LEU C 1 38  ? 41.040  101.925 30.914  1.00 23.42  ? 38  LEU C CD1 1 
ATOM   4275  C  CD2 . LEU C 1 38  ? 40.960  102.686 28.512  1.00 27.70  ? 38  LEU C CD2 1 
ATOM   4276  N  N   . ILE C 1 39  ? 44.065  99.680  30.747  1.00 26.89  ? 39  ILE C N   1 
ATOM   4277  C  CA  . ILE C 1 39  ? 44.002  98.329  30.210  1.00 24.73  ? 39  ILE C CA  1 
ATOM   4278  C  C   . ILE C 1 39  ? 42.549  97.911  30.253  1.00 26.94  ? 39  ILE C C   1 
ATOM   4279  O  O   . ILE C 1 39  ? 41.932  97.903  31.325  1.00 29.61  ? 39  ILE C O   1 
ATOM   4280  C  CB  . ILE C 1 39  ? 44.892  97.337  30.967  1.00 27.09  ? 39  ILE C CB  1 
ATOM   4281  C  CG1 . ILE C 1 39  ? 46.364  97.729  30.831  1.00 25.62  ? 39  ILE C CG1 1 
ATOM   4282  C  CG2 . ILE C 1 39  ? 44.691  95.937  30.379  1.00 26.65  ? 39  ILE C CG2 1 
ATOM   4283  C  CD1 . ILE C 1 39  ? 46.846  98.729  31.840  1.00 27.92  ? 39  ILE C CD1 1 
ATOM   4284  N  N   . THR C 1 40  ? 41.983  97.627  29.080  1.00 29.73  ? 40  THR C N   1 
ATOM   4285  C  CA  . THR C 1 40  ? 40.654  97.034  28.999  1.00 29.28  ? 40  THR C CA  1 
ATOM   4286  C  C   . THR C 1 40  ? 40.829  95.527  29.026  1.00 32.23  ? 40  THR C C   1 
ATOM   4287  O  O   . THR C 1 40  ? 41.620  94.971  28.257  1.00 35.47  ? 40  THR C O   1 
ATOM   4288  C  CB  . THR C 1 40  ? 39.896  97.467  27.738  1.00 26.46  ? 40  THR C CB  1 
ATOM   4289  O  OG1 . THR C 1 40  ? 40.681  97.168  26.573  1.00 26.54  ? 40  THR C OG1 1 
ATOM   4290  C  CG2 . THR C 1 40  ? 39.606  98.971  27.770  1.00 28.79  ? 40  THR C CG2 1 
ATOM   4291  N  N   . HIS C 1 41  ? 40.125  94.877  29.941  1.00 34.56  ? 41  HIS C N   1 
ATOM   4292  C  CA  . HIS C 1 41  ? 40.269  93.464  30.172  1.00 34.01  ? 41  HIS C CA  1 
ATOM   4293  C  C   . HIS C 1 41  ? 38.854  92.936  30.345  1.00 28.86  ? 41  HIS C C   1 
ATOM   4294  O  O   . HIS C 1 41  ? 38.017  93.614  30.956  1.00 33.34  ? 41  HIS C O   1 
ATOM   4295  C  CB  . HIS C 1 41  ? 41.127  93.180  31.420  1.00 29.48  ? 41  HIS C CB  1 
ATOM   4296  C  CG  . HIS C 1 41  ? 41.574  91.754  31.547  1.00 33.68  ? 41  HIS C CG  1 
ATOM   4297  N  ND1 . HIS C 1 41  ? 40.767  90.758  32.060  1.00 31.20  ? 41  HIS C ND1 1 
ATOM   4298  C  CD2 . HIS C 1 41  ? 42.751  91.158  31.226  1.00 31.15  ? 41  HIS C CD2 1 
ATOM   4299  C  CE1 . HIS C 1 41  ? 41.427  89.610  32.046  1.00 32.91  ? 41  HIS C CE1 1 
ATOM   4300  N  NE2 . HIS C 1 41  ? 42.633  89.827  31.550  1.00 31.70  ? 41  HIS C NE2 1 
ATOM   4301  N  N   . PRO C 1 42  ? 38.546  91.761  29.798  1.00 32.63  ? 42  PRO C N   1 
ATOM   4302  C  CA  . PRO C 1 42  ? 37.197  91.203  29.980  1.00 32.10  ? 42  PRO C CA  1 
ATOM   4303  C  C   . PRO C 1 42  ? 36.786  91.113  31.437  1.00 36.80  ? 42  PRO C C   1 
ATOM   4304  O  O   . PRO C 1 42  ? 35.601  91.289  31.756  1.00 32.97  ? 42  PRO C O   1 
ATOM   4305  C  CB  . PRO C 1 42  ? 37.282  89.811  29.340  1.00 30.54  ? 42  PRO C CB  1 
ATOM   4306  C  CG  . PRO C 1 42  ? 38.588  89.711  28.690  1.00 38.11  ? 42  PRO C CG  1 
ATOM   4307  C  CD  . PRO C 1 42  ? 39.431  90.897  29.006  1.00 34.41  ? 42  PRO C CD  1 
ATOM   4308  N  N   . LYS C 1 43  ? 37.731  90.876  32.347  1.00 33.86  ? 43  LYS C N   1 
ATOM   4309  C  CA  . LYS C 1 43  ? 37.345  90.803  33.750  1.00 33.60  ? 43  LYS C CA  1 
ATOM   4310  C  C   . LYS C 1 43  ? 37.300  92.169  34.421  1.00 32.46  ? 43  LYS C C   1 
ATOM   4311  O  O   . LYS C 1 43  ? 36.942  92.247  35.600  1.00 33.15  ? 43  LYS C O   1 
ATOM   4312  C  CB  . LYS C 1 43  ? 38.289  89.873  34.516  1.00 32.70  ? 43  LYS C CB  1 
ATOM   4313  C  CG  . LYS C 1 43  ? 38.130  88.401  34.167  1.00 33.93  ? 43  LYS C CG  1 
ATOM   4314  C  CD  . LYS C 1 43  ? 39.476  87.696  34.172  1.00 42.85  ? 43  LYS C CD  1 
ATOM   4315  C  CE  . LYS C 1 43  ? 39.520  86.578  35.208  1.00 56.75  ? 43  LYS C CE  1 
ATOM   4316  N  NZ  . LYS C 1 43  ? 40.866  85.920  35.253  1.00 58.70  ? 43  LYS C NZ  1 
ATOM   4317  N  N   . GLY C 1 44  ? 37.647  93.233  33.727  1.00 31.59  ? 44  GLY C N   1 
ATOM   4318  C  CA  . GLY C 1 44  ? 37.546  94.557  34.315  1.00 30.72  ? 44  GLY C CA  1 
ATOM   4319  C  C   . GLY C 1 44  ? 38.592  95.521  33.786  1.00 31.10  ? 44  GLY C C   1 
ATOM   4320  O  O   . GLY C 1 44  ? 39.706  95.155  33.414  1.00 27.29  ? 44  GLY C O   1 
ATOM   4321  N  N   . ASN C 1 45  ? 38.222  96.794  33.770  1.00 29.21  ? 45  ASN C N   1 
ATOM   4322  C  CA  . ASN C 1 45  ? 39.106  97.857  33.326  1.00 30.52  ? 45  ASN C CA  1 
ATOM   4323  C  C   . ASN C 1 45  ? 40.112  98.201  34.422  1.00 26.90  ? 45  ASN C C   1 
ATOM   4324  O  O   . ASN C 1 45  ? 39.794  98.182  35.618  1.00 24.83  ? 45  ASN C O   1 
ATOM   4325  C  CB  . ASN C 1 45  ? 38.281  99.097  32.935  1.00 25.65  ? 45  ASN C CB  1 
ATOM   4326  C  CG  . ASN C 1 45  ? 37.310  98.803  31.791  1.00 29.62  ? 45  ASN C CG  1 
ATOM   4327  O  OD1 . ASN C 1 45  ? 37.723  98.321  30.747  1.00 29.68  ? 45  ASN C OD1 1 
ATOM   4328  N  ND2 . ASN C 1 45  ? 36.015  99.022  32.016  1.00 25.94  ? 45  ASN C ND2 1 
ATOM   4329  N  N   . VAL C 1 46  ? 41.333  98.510  33.994  1.00 22.92  ? 46  VAL C N   1 
ATOM   4330  C  CA  . VAL C 1 46  ? 42.455  98.823  34.873  1.00 24.95  ? 46  VAL C CA  1 
ATOM   4331  C  C   . VAL C 1 46  ? 43.011  100.188 34.486  1.00 24.85  ? 46  VAL C C   1 
ATOM   4332  O  O   . VAL C 1 46  ? 43.287  100.439 33.307  1.00 22.93  ? 46  VAL C O   1 
ATOM   4333  C  CB  . VAL C 1 46  ? 43.555  97.753  34.773  1.00 25.45  ? 46  VAL C CB  1 
ATOM   4334  C  CG1 . VAL C 1 46  ? 44.740  98.107  35.687  1.00 23.73  ? 46  VAL C CG1 1 
ATOM   4335  C  CG2 . VAL C 1 46  ? 42.980  96.398  35.106  1.00 24.15  ? 46  VAL C CG2 1 
ATOM   4336  N  N   . VAL C 1 47  ? 43.203  101.051 35.475  1.00 22.54  ? 47  VAL C N   1 
ATOM   4337  C  CA  . VAL C 1 47  ? 43.845  102.349 35.286  1.00 21.79  ? 47  VAL C CA  1 
ATOM   4338  C  C   . VAL C 1 47  ? 45.186  102.327 36.017  1.00 24.22  ? 47  VAL C C   1 
ATOM   4339  O  O   . VAL C 1 47  ? 45.235  101.992 37.205  1.00 26.48  ? 47  VAL C O   1 
ATOM   4340  C  CB  . VAL C 1 47  ? 42.959  103.493 35.812  1.00 22.36  ? 47  VAL C CB  1 
ATOM   4341  C  CG1 . VAL C 1 47  ? 43.765  104.770 35.940  1.00 26.54  ? 47  VAL C CG1 1 
ATOM   4342  C  CG2 . VAL C 1 47  ? 41.739  103.697 34.906  1.00 27.08  ? 47  VAL C CG2 1 
ATOM   4343  N  N   . ILE C 1 48  ? 46.269  102.689 35.330  1.00 22.84  ? 48  ILE C N   1 
ATOM   4344  C  CA  . ILE C 1 48  ? 47.585  102.812 35.960  1.00 21.17  ? 48  ILE C CA  1 
ATOM   4345  C  C   . ILE C 1 48  ? 47.885  104.295 36.205  1.00 23.76  ? 48  ILE C C   1 
ATOM   4346  O  O   . ILE C 1 48  ? 48.062  105.076 35.254  1.00 22.46  ? 48  ILE C O   1 
ATOM   4347  C  CB  . ILE C 1 48  ? 48.688  102.141 35.130  1.00 22.88  ? 48  ILE C CB  1 
ATOM   4348  C  CG1 . ILE C 1 48  ? 48.456  100.630 34.996  1.00 24.50  ? 48  ILE C CG1 1 
ATOM   4349  C  CG2 . ILE C 1 48  ? 50.074  102.401 35.738  1.00 20.99  ? 48  ILE C CG2 1 
ATOM   4350  C  CD1 . ILE C 1 48  ? 49.537  99.948  34.169  1.00 23.93  ? 48  ILE C CD1 1 
ATOM   4351  N  N   . ASP C 1 49  ? 47.924  104.671 37.498  1.00 20.87  ? 49  ASP C N   1 
ATOM   4352  C  CA  . ASP C 1 49  ? 48.367  105.965 38.043  1.00 22.35  ? 49  ASP C CA  1 
ATOM   4353  C  C   . ASP C 1 49  ? 47.377  107.099 37.805  1.00 26.87  ? 49  ASP C C   1 
ATOM   4354  O  O   . ASP C 1 49  ? 46.962  107.763 38.763  1.00 23.73  ? 49  ASP C O   1 
ATOM   4355  C  CB  . ASP C 1 49  ? 49.732  106.371 37.489  1.00 24.58  ? 49  ASP C CB  1 
ATOM   4356  C  CG  . ASP C 1 49  ? 50.867  105.567 38.101  1.00 25.41  ? 49  ASP C CG  1 
ATOM   4357  O  OD1 . ASP C 1 49  ? 50.726  105.105 39.255  1.00 24.56  ? 49  ASP C OD1 1 
ATOM   4358  O  OD2 . ASP C 1 49  ? 51.893  105.379 37.421  1.00 21.68  ? 49  ASP C OD2 1 
ATOM   4359  N  N   . GLY C 1 50  ? 47.004  107.340 36.542  1.00 26.51  ? 50  GLY C N   1 
ATOM   4360  C  CA  . GLY C 1 50  ? 46.031  108.358 36.226  1.00 28.98  ? 50  GLY C CA  1 
ATOM   4361  C  C   . GLY C 1 50  ? 46.578  109.758 36.007  1.00 29.45  ? 50  GLY C C   1 
ATOM   4362  O  O   . GLY C 1 50  ? 45.786  110.704 35.952  1.00 26.53  ? 50  GLY C O   1 
ATOM   4363  N  N   . GLY C 1 51  ? 47.897  109.926 35.880  1.00 26.62  ? 51  GLY C N   1 
ATOM   4364  C  CA  . GLY C 1 51  ? 48.453  111.242 35.587  1.00 29.68  ? 51  GLY C CA  1 
ATOM   4365  C  C   . GLY C 1 51  ? 48.312  112.239 36.734  1.00 29.93  ? 51  GLY C C   1 
ATOM   4366  O  O   . GLY C 1 51  ? 48.039  111.895 37.896  1.00 32.98  ? 51  GLY C O   1 
ATOM   4367  N  N   . CYS C 1 52  ? 48.514  113.505 36.386  1.00 25.16  ? 52  CYS C N   1 
ATOM   4368  C  CA  . CYS C 1 52  ? 48.342  114.583 37.353  1.00 29.61  ? 52  CYS C CA  1 
ATOM   4369  C  C   . CYS C 1 52  ? 46.869  114.728 37.712  1.00 27.62  ? 52  CYS C C   1 
ATOM   4370  O  O   . CYS C 1 52  ? 45.982  114.509 36.881  1.00 29.35  ? 52  CYS C O   1 
ATOM   4371  C  CB  . CYS C 1 52  ? 48.875  115.911 36.800  1.00 25.18  ? 52  CYS C CB  1 
ATOM   4372  S  SG  . CYS C 1 52  ? 50.573  115.836 36.204  1.00 28.33  ? 52  CYS C SG  1 
ATOM   4373  N  N   . ALA C 1 53  ? 46.607  115.092 38.964  1.00 22.82  ? 53  ALA C N   1 
ATOM   4374  C  CA  . ALA C 1 53  ? 45.223  115.289 39.390  1.00 29.04  ? 53  ALA C CA  1 
ATOM   4375  C  C   . ALA C 1 53  ? 44.524  116.325 38.515  1.00 34.35  ? 53  ALA C C   1 
ATOM   4376  O  O   . ALA C 1 53  ? 45.111  117.350 38.150  1.00 31.45  ? 53  ALA C O   1 
ATOM   4377  C  CB  . ALA C 1 53  ? 45.162  115.738 40.852  1.00 28.54  ? 53  ALA C CB  1 
ATOM   4378  N  N   . VAL C 1 54  ? 43.247  116.068 38.211  1.00 32.46  ? 54  VAL C N   1 
ATOM   4379  C  CA  . VAL C 1 54  ? 42.489  116.989 37.368  1.00 37.38  ? 54  VAL C CA  1 
ATOM   4380  C  C   . VAL C 1 54  ? 42.435  118.378 37.994  1.00 35.86  ? 54  VAL C C   1 
ATOM   4381  O  O   . VAL C 1 54  ? 42.429  119.382 37.279  1.00 36.28  ? 54  VAL C O   1 
ATOM   4382  C  CB  . VAL C 1 54  ? 41.074  116.440 37.077  1.00 37.00  ? 54  VAL C CB  1 
ATOM   4383  C  CG1 . VAL C 1 54  ? 40.168  116.509 38.323  1.00 33.46  ? 54  VAL C CG1 1 
ATOM   4384  C  CG2 . VAL C 1 54  ? 40.457  117.213 35.925  1.00 38.81  ? 54  VAL C CG2 1 
ATOM   4385  N  N   . GLU C 1 55  ? 42.445  118.466 39.327  1.00 37.26  ? 55  GLU C N   1 
ATOM   4386  C  CA  . GLU C 1 55  ? 42.477  119.773 39.971  1.00 39.05  ? 55  GLU C CA  1 
ATOM   4387  C  C   . GLU C 1 55  ? 43.646  120.627 39.484  1.00 41.55  ? 55  GLU C C   1 
ATOM   4388  O  O   . GLU C 1 55  ? 43.600  121.854 39.616  1.00 38.93  ? 55  GLU C O   1 
ATOM   4389  C  CB  . GLU C 1 55  ? 42.549  119.602 41.487  1.00 37.36  ? 55  GLU C CB  1 
ATOM   4390  C  CG  . GLU C 1 55  ? 41.263  119.126 42.116  1.00 38.89  ? 55  GLU C CG  1 
ATOM   4391  C  CD  . GLU C 1 55  ? 41.108  117.613 42.050  1.00 38.11  ? 55  GLU C CD  1 
ATOM   4392  O  OE1 . GLU C 1 55  ? 41.767  116.972 41.196  1.00 36.70  ? 55  GLU C OE1 1 
ATOM   4393  O  OE2 . GLU C 1 55  ? 40.325  117.065 42.852  1.00 34.76  ? 55  GLU C OE2 1 
ATOM   4394  N  N   . CYS C 1 56  ? 44.677  120.005 38.897  1.00 40.12  ? 56  CYS C N   1 
ATOM   4395  C  CA  . CYS C 1 56  ? 45.869  120.713 38.454  1.00 36.26  ? 56  CYS C CA  1 
ATOM   4396  C  C   . CYS C 1 56  ? 45.635  121.523 37.197  1.00 42.94  ? 56  CYS C C   1 
ATOM   4397  O  O   . CYS C 1 56  ? 46.485  122.356 36.847  1.00 40.79  ? 56  CYS C O   1 
ATOM   4398  C  CB  . CYS C 1 56  ? 47.007  119.728 38.172  1.00 35.50  ? 56  CYS C CB  1 
ATOM   4399  S  SG  . CYS C 1 56  ? 47.699  119.015 39.639  1.00 41.52  ? 56  CYS C SG  1 
ATOM   4400  N  N   . ALA C 1 57  ? 44.544  121.247 36.478  1.00 42.19  ? 57  ALA C N   1 
ATOM   4401  C  CA  . ALA C 1 57  ? 44.243  121.994 35.267  1.00 42.42  ? 57  ALA C CA  1 
ATOM   4402  C  C   . ALA C 1 57  ? 43.750  123.395 35.578  1.00 43.59  ? 57  ALA C C   1 
ATOM   4403  O  O   . ALA C 1 57  ? 43.897  124.292 34.740  1.00 41.44  ? 57  ALA C O   1 
ATOM   4404  C  CB  . ALA C 1 57  ? 43.205  121.248 34.432  1.00 42.91  ? 57  ALA C CB  1 
ATOM   4405  N  N   . SER C 1 58  ? 43.177  123.595 36.766  1.00 43.89  ? 58  SER C N   1 
ATOM   4406  C  CA  . SER C 1 58  ? 42.613  124.876 37.168  1.00 44.59  ? 58  SER C CA  1 
ATOM   4407  C  C   . SER C 1 58  ? 43.521  125.621 38.140  1.00 50.38  ? 58  SER C C   1 
ATOM   4408  O  O   . SER C 1 58  ? 43.952  126.744 37.859  1.00 55.45  ? 58  SER C O   1 
ATOM   4409  C  CB  . SER C 1 58  ? 41.237  124.645 37.794  1.00 46.60  ? 58  SER C CB  1 
ATOM   4410  O  OG  . SER C 1 58  ? 40.297  124.318 36.788  1.00 57.48  ? 58  SER C OG  1 
ATOM   4411  N  N   . ASP C 1 59  ? 43.845  124.993 39.269  1.00 50.84  ? 59  ASP C N   1 
ATOM   4412  C  CA  . ASP C 1 59  ? 44.530  125.636 40.391  1.00 47.24  ? 59  ASP C CA  1 
ATOM   4413  C  C   . ASP C 1 59  ? 45.782  124.838 40.765  1.00 44.34  ? 59  ASP C C   1 
ATOM   4414  O  O   . ASP C 1 59  ? 45.842  124.223 41.836  1.00 47.18  ? 59  ASP C O   1 
ATOM   4415  C  CB  . ASP C 1 59  ? 43.566  125.750 41.576  1.00 49.44  ? 59  ASP C CB  1 
ATOM   4416  C  CG  . ASP C 1 59  ? 44.072  126.669 42.671  1.00 50.61  ? 59  ASP C CG  1 
ATOM   4417  O  OD1 . ASP C 1 59  ? 45.088  127.362 42.451  1.00 50.65  ? 59  ASP C OD1 1 
ATOM   4418  O  OD2 . ASP C 1 59  ? 43.452  126.690 43.759  1.00 52.13  ? 59  ASP C OD2 1 
ATOM   4419  N  N   . PRO C 1 60  ? 46.811  124.842 39.908  1.00 40.02  ? 60  PRO C N   1 
ATOM   4420  C  CA  . PRO C 1 60  ? 48.038  124.083 40.247  1.00 42.22  ? 60  PRO C CA  1 
ATOM   4421  C  C   . PRO C 1 60  ? 48.686  124.533 41.549  1.00 44.25  ? 60  PRO C C   1 
ATOM   4422  O  O   . PRO C 1 60  ? 48.941  123.707 42.438  1.00 40.68  ? 60  PRO C O   1 
ATOM   4423  C  CB  . PRO C 1 60  ? 48.970  124.336 39.048  1.00 39.80  ? 60  PRO C CB  1 
ATOM   4424  C  CG  . PRO C 1 60  ? 48.249  125.166 38.090  1.00 40.43  ? 60  PRO C CG  1 
ATOM   4425  C  CD  . PRO C 1 60  ? 46.901  125.538 38.615  1.00 44.04  ? 60  PRO C CD  1 
ATOM   4426  N  N   . LYS C 1 61  ? 48.974  125.834 41.675  1.00 45.18  ? 61  LYS C N   1 
ATOM   4427  C  CA  . LYS C 1 61  ? 49.503  126.369 42.925  1.00 45.13  ? 61  LYS C CA  1 
ATOM   4428  C  C   . LYS C 1 61  ? 48.613  125.992 44.102  1.00 41.50  ? 61  LYS C C   1 
ATOM   4429  O  O   . LYS C 1 61  ? 49.104  125.588 45.160  1.00 42.08  ? 61  LYS C O   1 
ATOM   4430  C  CB  . LYS C 1 61  ? 49.637  127.894 42.828  1.00 45.84  ? 61  LYS C CB  1 
ATOM   4431  C  CG  . LYS C 1 61  ? 50.530  128.503 43.898  1.00 42.94  ? 61  LYS C CG  1 
ATOM   4432  C  CD  . LYS C 1 61  ? 51.975  128.556 43.434  1.00 50.40  ? 61  LYS C CD  1 
ATOM   4433  C  CE  . LYS C 1 61  ? 52.806  129.466 44.323  1.00 52.20  ? 61  LYS C CE  1 
ATOM   4434  N  NZ  . LYS C 1 61  ? 52.332  129.385 45.726  1.00 51.86  ? 61  LYS C NZ  1 
ATOM   4435  N  N   . GLY C 1 62  ? 47.298  126.113 43.936  1.00 43.50  ? 62  GLY C N   1 
ATOM   4436  C  CA  . GLY C 1 62  ? 46.401  125.786 45.033  1.00 43.81  ? 62  GLY C CA  1 
ATOM   4437  C  C   . GLY C 1 62  ? 46.422  124.317 45.418  1.00 40.73  ? 62  GLY C C   1 
ATOM   4438  O  O   . GLY C 1 62  ? 46.317  123.978 46.598  1.00 41.62  ? 62  GLY C O   1 
ATOM   4439  N  N   . TYR C 1 63  ? 46.566  123.425 44.435  1.00 38.91  ? 63  TYR C N   1 
ATOM   4440  C  CA  . TYR C 1 63  ? 46.491  121.994 44.724  1.00 40.44  ? 63  TYR C CA  1 
ATOM   4441  C  C   . TYR C 1 63  ? 47.864  121.385 45.031  1.00 37.80  ? 63  TYR C C   1 
ATOM   4442  O  O   . TYR C 1 63  ? 48.018  120.676 46.025  1.00 36.95  ? 63  TYR C O   1 
ATOM   4443  C  CB  . TYR C 1 63  ? 45.819  121.249 43.560  1.00 33.88  ? 63  TYR C CB  1 
ATOM   4444  C  CG  . TYR C 1 63  ? 45.300  119.886 43.958  1.00 38.71  ? 63  TYR C CG  1 
ATOM   4445  C  CD1 . TYR C 1 63  ? 44.219  119.758 44.812  1.00 33.15  ? 63  TYR C CD1 1 
ATOM   4446  C  CD2 . TYR C 1 63  ? 45.930  118.720 43.513  1.00 35.75  ? 63  TYR C CD2 1 
ATOM   4447  C  CE1 . TYR C 1 63  ? 43.757  118.511 45.194  1.00 35.88  ? 63  TYR C CE1 1 
ATOM   4448  C  CE2 . TYR C 1 63  ? 45.473  117.471 43.894  1.00 31.17  ? 63  TYR C CE2 1 
ATOM   4449  C  CZ  . TYR C 1 63  ? 44.384  117.372 44.724  1.00 33.34  ? 63  TYR C CZ  1 
ATOM   4450  O  OH  . TYR C 1 63  ? 43.942  116.126 45.097  1.00 30.92  ? 63  TYR C OH  1 
ATOM   4451  N  N   . TRP C 1 64  ? 48.870  121.655 44.204  1.00 38.24  ? 64  TRP C N   1 
ATOM   4452  C  CA  . TRP C 1 64  ? 50.201  121.094 44.407  1.00 34.05  ? 64  TRP C CA  1 
ATOM   4453  C  C   . TRP C 1 64  ? 51.068  121.894 45.377  1.00 39.11  ? 64  TRP C C   1 
ATOM   4454  O  O   . TRP C 1 64  ? 51.946  121.313 46.024  1.00 39.57  ? 64  TRP C O   1 
ATOM   4455  C  CB  . TRP C 1 64  ? 50.932  120.992 43.075  1.00 33.12  ? 64  TRP C CB  1 
ATOM   4456  C  CG  . TRP C 1 64  ? 50.625  119.767 42.318  1.00 33.86  ? 64  TRP C CG  1 
ATOM   4457  C  CD1 . TRP C 1 64  ? 49.694  118.810 42.629  1.00 29.08  ? 64  TRP C CD1 1 
ATOM   4458  C  CD2 . TRP C 1 64  ? 51.257  119.341 41.113  1.00 30.65  ? 64  TRP C CD2 1 
ATOM   4459  N  NE1 . TRP C 1 64  ? 49.701  117.832 41.677  1.00 29.65  ? 64  TRP C NE1 1 
ATOM   4460  C  CE2 . TRP C 1 64  ? 50.657  118.127 40.737  1.00 30.06  ? 64  TRP C CE2 1 
ATOM   4461  C  CE3 . TRP C 1 64  ? 52.283  119.861 40.326  1.00 28.05  ? 64  TRP C CE3 1 
ATOM   4462  C  CZ2 . TRP C 1 64  ? 51.050  117.420 39.606  1.00 29.43  ? 64  TRP C CZ2 1 
ATOM   4463  C  CZ3 . TRP C 1 64  ? 52.671  119.162 39.194  1.00 29.54  ? 64  TRP C CZ3 1 
ATOM   4464  C  CH2 . TRP C 1 64  ? 52.053  117.956 38.843  1.00 28.18  ? 64  TRP C CH2 1 
ATOM   4465  N  N   . GLY C 1 65  ? 50.884  123.214 45.468  1.00 44.02  ? 65  GLY C N   1 
ATOM   4466  C  CA  . GLY C 1 65  ? 51.668  124.003 46.410  1.00 40.83  ? 65  GLY C CA  1 
ATOM   4467  C  C   . GLY C 1 65  ? 53.043  124.379 45.882  1.00 41.69  ? 65  GLY C C   1 
ATOM   4468  O  O   . GLY C 1 65  ? 53.259  124.529 44.674  1.00 40.33  ? 65  GLY C O   1 
ATOM   4469  N  N   . ASP C 1 66  ? 53.993  124.495 46.818  1.00 42.42  ? 66  ASP C N   1 
ATOM   4470  C  CA  . ASP C 1 66  ? 55.300  125.069 46.500  1.00 40.61  ? 66  ASP C CA  1 
ATOM   4471  C  C   . ASP C 1 66  ? 56.028  124.281 45.425  1.00 44.73  ? 66  ASP C C   1 
ATOM   4472  O  O   . ASP C 1 66  ? 56.842  124.853 44.683  1.00 40.98  ? 66  ASP C O   1 
ATOM   4473  C  CB  . ASP C 1 66  ? 56.168  125.150 47.755  1.00 47.71  ? 66  ASP C CB  1 
ATOM   4474  C  CG  . ASP C 1 66  ? 55.633  126.146 48.762  1.00 52.41  ? 66  ASP C CG  1 
ATOM   4475  O  OD1 . ASP C 1 66  ? 54.761  126.946 48.360  1.00 52.14  ? 66  ASP C OD1 1 
ATOM   4476  O  OD2 . ASP C 1 66  ? 56.082  126.141 49.931  1.00 62.42  ? 66  ASP C OD2 1 
ATOM   4477  N  N   . ILE C 1 67  ? 55.756  122.975 45.323  1.00 41.60  ? 67  ILE C N   1 
ATOM   4478  C  CA  . ILE C 1 67  ? 56.430  122.136 44.345  1.00 37.07  ? 67  ILE C CA  1 
ATOM   4479  C  C   . ILE C 1 67  ? 56.193  122.613 42.918  1.00 37.21  ? 67  ILE C C   1 
ATOM   4480  O  O   . ILE C 1 67  ? 56.924  122.206 42.003  1.00 39.47  ? 67  ILE C O   1 
ATOM   4481  C  CB  . ILE C 1 67  ? 55.990  120.658 44.529  1.00 38.86  ? 67  ILE C CB  1 
ATOM   4482  C  CG1 . ILE C 1 67  ? 56.898  119.700 43.741  1.00 34.88  ? 67  ILE C CG1 1 
ATOM   4483  C  CG2 . ILE C 1 67  ? 54.535  120.464 44.115  1.00 32.05  ? 67  ILE C CG2 1 
ATOM   4484  C  CD1 . ILE C 1 67  ? 58.159  119.302 44.481  1.00 37.21  ? 67  ILE C CD1 1 
ATOM   4485  N  N   . THR C 1 68  ? 55.203  123.485 42.696  1.00 37.75  ? 68  THR C N   1 
ATOM   4486  C  CA  . THR C 1 68  ? 54.989  124.009 41.350  1.00 38.98  ? 68  THR C CA  1 
ATOM   4487  C  C   . THR C 1 68  ? 56.156  124.861 40.873  1.00 40.76  ? 68  THR C C   1 
ATOM   4488  O  O   . THR C 1 68  ? 56.312  125.046 39.663  1.00 40.21  ? 68  THR C O   1 
ATOM   4489  C  CB  . THR C 1 68  ? 53.690  124.823 41.267  1.00 42.75  ? 68  THR C CB  1 
ATOM   4490  O  OG1 . THR C 1 68  ? 53.498  125.591 42.461  1.00 37.71  ? 68  THR C OG1 1 
ATOM   4491  C  CG2 . THR C 1 68  ? 52.490  123.894 41.075  1.00 42.36  ? 68  THR C CG2 1 
ATOM   4492  N  N   . SER C 1 69  ? 56.992  125.365 41.788  1.00 40.30  ? 69  SER C N   1 
ATOM   4493  C  CA  . SER C 1 69  ? 58.204  126.062 41.363  1.00 42.81  ? 69  SER C CA  1 
ATOM   4494  C  C   . SER C 1 69  ? 59.203  125.126 40.691  1.00 45.66  ? 69  SER C C   1 
ATOM   4495  O  O   . SER C 1 69  ? 60.085  125.593 39.961  1.00 47.66  ? 69  SER C O   1 
ATOM   4496  C  CB  . SER C 1 69  ? 58.873  126.734 42.557  1.00 48.47  ? 69  SER C CB  1 
ATOM   4497  O  OG  . SER C 1 69  ? 59.674  125.802 43.267  1.00 47.50  ? 69  SER C OG  1 
ATOM   4498  N  N   . VAL C 1 70  ? 59.102  123.824 40.936  1.00 41.55  ? 70  VAL C N   1 
ATOM   4499  C  CA  . VAL C 1 70  ? 59.974  122.845 40.310  1.00 40.12  ? 70  VAL C CA  1 
ATOM   4500  C  C   . VAL C 1 70  ? 59.289  122.167 39.131  1.00 41.19  ? 70  VAL C C   1 
ATOM   4501  O  O   . VAL C 1 70  ? 59.892  121.995 38.071  1.00 43.33  ? 70  VAL C O   1 
ATOM   4502  C  CB  . VAL C 1 70  ? 60.441  121.798 41.348  1.00 42.62  ? 70  VAL C CB  1 
ATOM   4503  C  CG1 . VAL C 1 70  ? 61.434  120.822 40.713  1.00 40.21  ? 70  VAL C CG1 1 
ATOM   4504  C  CG2 . VAL C 1 70  ? 61.036  122.466 42.580  1.00 36.85  ? 70  VAL C CG2 1 
ATOM   4505  N  N   . TYR C 1 71  ? 58.024  121.781 39.305  1.00 39.43  ? 71  TYR C N   1 
ATOM   4506  C  CA  . TYR C 1 71  ? 57.258  121.068 38.288  1.00 39.44  ? 71  TYR C CA  1 
ATOM   4507  C  C   . TYR C 1 71  ? 55.980  121.857 38.028  1.00 38.03  ? 71  TYR C C   1 
ATOM   4508  O  O   . TYR C 1 71  ? 55.076  121.876 38.873  1.00 39.24  ? 71  TYR C O   1 
ATOM   4509  C  CB  . TYR C 1 71  ? 56.941  119.639 38.748  1.00 40.07  ? 71  TYR C CB  1 
ATOM   4510  C  CG  . TYR C 1 71  ? 58.148  118.765 39.018  1.00 40.12  ? 71  TYR C CG  1 
ATOM   4511  C  CD1 . TYR C 1 71  ? 58.908  118.246 37.968  1.00 40.34  ? 71  TYR C CD1 1 
ATOM   4512  C  CD2 . TYR C 1 71  ? 58.536  118.467 40.322  1.00 36.31  ? 71  TYR C CD2 1 
ATOM   4513  C  CE1 . TYR C 1 71  ? 60.006  117.443 38.209  1.00 38.02  ? 71  TYR C CE1 1 
ATOM   4514  C  CE2 . TYR C 1 71  ? 59.636  117.671 40.574  1.00 32.52  ? 71  TYR C CE2 1 
ATOM   4515  C  CZ  . TYR C 1 71  ? 60.370  117.165 39.514  1.00 42.74  ? 71  TYR C CZ  1 
ATOM   4516  O  OH  . TYR C 1 71  ? 61.471  116.372 39.753  1.00 50.28  ? 71  TYR C OH  1 
ATOM   4517  N  N   . TRP C 1 72  ? 55.901  122.523 36.874  1.00 38.05  ? 72  TRP C N   1 
ATOM   4518  C  CA  . TRP C 1 72  ? 54.684  123.248 36.534  1.00 39.81  ? 72  TRP C CA  1 
ATOM   4519  C  C   . TRP C 1 72  ? 53.835  122.384 35.621  1.00 37.45  ? 72  TRP C C   1 
ATOM   4520  O  O   . TRP C 1 72  ? 54.292  122.021 34.525  1.00 34.61  ? 72  TRP C O   1 
ATOM   4521  C  CB  . TRP C 1 72  ? 54.972  124.595 35.864  1.00 42.44  ? 72  TRP C CB  1 
ATOM   4522  C  CG  . TRP C 1 72  ? 53.691  125.381 35.711  1.00 40.67  ? 72  TRP C CG  1 
ATOM   4523  C  CD1 . TRP C 1 72  ? 52.937  125.508 34.577  1.00 40.94  ? 72  TRP C CD1 1 
ATOM   4524  C  CD2 . TRP C 1 72  ? 52.978  126.077 36.744  1.00 38.38  ? 72  TRP C CD2 1 
ATOM   4525  N  NE1 . TRP C 1 72  ? 51.814  126.257 34.839  1.00 41.03  ? 72  TRP C NE1 1 
ATOM   4526  C  CE2 . TRP C 1 72  ? 51.814  126.614 36.162  1.00 37.44  ? 72  TRP C CE2 1 
ATOM   4527  C  CE3 . TRP C 1 72  ? 53.217  126.309 38.100  1.00 45.04  ? 72  TRP C CE3 1 
ATOM   4528  C  CZ2 . TRP C 1 72  ? 50.902  127.370 36.884  1.00 39.33  ? 72  TRP C CZ2 1 
ATOM   4529  C  CZ3 . TRP C 1 72  ? 52.300  127.059 38.821  1.00 40.68  ? 72  TRP C CZ3 1 
ATOM   4530  C  CH2 . TRP C 1 72  ? 51.160  127.575 38.212  1.00 40.44  ? 72  TRP C CH2 1 
ATOM   4531  N  N   . PRO C 1 73  ? 52.620  122.036 36.027  1.00 33.16  ? 73  PRO C N   1 
ATOM   4532  C  CA  . PRO C 1 73  ? 51.784  121.153 35.209  1.00 36.83  ? 73  PRO C CA  1 
ATOM   4533  C  C   . PRO C 1 73  ? 50.980  121.922 34.168  1.00 40.59  ? 73  PRO C C   1 
ATOM   4534  O  O   . PRO C 1 73  ? 50.365  122.947 34.477  1.00 40.13  ? 73  PRO C O   1 
ATOM   4535  C  CB  . PRO C 1 73  ? 50.875  120.496 36.249  1.00 28.52  ? 73  PRO C CB  1 
ATOM   4536  C  CG  . PRO C 1 73  ? 50.691  121.572 37.281  1.00 32.68  ? 73  PRO C CG  1 
ATOM   4537  C  CD  . PRO C 1 73  ? 51.958  122.404 37.292  1.00 34.78  ? 73  PRO C CD  1 
ATOM   4538  N  N   . VAL C 1 74  ? 50.970  121.428 32.936  1.00 36.73  ? 74  VAL C N   1 
ATOM   4539  C  CA  . VAL C 1 74  ? 50.302  122.085 31.815  1.00 36.98  ? 74  VAL C CA  1 
ATOM   4540  C  C   . VAL C 1 74  ? 49.361  121.054 31.203  1.00 37.68  ? 74  VAL C C   1 
ATOM   4541  O  O   . VAL C 1 74  ? 49.801  120.181 30.437  1.00 37.40  ? 74  VAL C O   1 
ATOM   4542  C  CB  . VAL C 1 74  ? 51.299  122.612 30.773  1.00 38.69  ? 74  VAL C CB  1 
ATOM   4543  C  CG1 . VAL C 1 74  ? 50.558  123.231 29.570  1.00 36.73  ? 74  VAL C CG1 1 
ATOM   4544  C  CG2 . VAL C 1 74  ? 52.267  123.609 31.410  1.00 36.81  ? 74  VAL C CG2 1 
ATOM   4545  N  N   . MET C 1 75  ? 48.069  121.163 31.517  1.00 35.29  ? 75  MET C N   1 
ATOM   4546  C  CA  . MET C 1 75  ? 47.064  120.228 31.022  1.00 41.81  ? 75  MET C CA  1 
ATOM   4547  C  C   . MET C 1 75  ? 45.696  120.910 31.020  1.00 42.79  ? 75  MET C C   1 
ATOM   4548  O  O   . MET C 1 75  ? 45.446  121.842 31.792  1.00 42.57  ? 75  MET C O   1 
ATOM   4549  C  CB  . MET C 1 75  ? 46.999  118.952 31.880  1.00 40.39  ? 75  MET C CB  1 
ATOM   4550  C  CG  . MET C 1 75  ? 46.317  119.150 33.227  1.00 39.33  ? 75  MET C CG  1 
ATOM   4551  S  SD  . MET C 1 75  ? 46.352  117.731 34.366  1.00 38.49  ? 75  MET C SD  1 
ATOM   4552  C  CE  . MET C 1 75  ? 44.729  116.985 34.107  1.00 33.46  ? 75  MET C CE  1 
ATOM   4553  N  N   . ARG C 1 76  ? 44.799  120.403 30.171  1.00 40.13  ? 76  ARG C N   1 
ATOM   4554  C  CA  . ARG C 1 76  ? 43.415  120.863 30.148  1.00 44.01  ? 76  ARG C CA  1 
ATOM   4555  C  C   . ARG C 1 76  ? 42.533  120.011 31.058  1.00 45.08  ? 76  ARG C C   1 
ATOM   4556  O  O   . ARG C 1 76  ? 42.898  118.913 31.479  1.00 46.14  ? 76  ARG C O   1 
ATOM   4557  C  CB  . ARG C 1 76  ? 42.870  120.846 28.719  1.00 45.94  ? 76  ARG C CB  1 
ATOM   4558  C  CG  . ARG C 1 76  ? 43.712  121.665 27.739  1.00 50.25  ? 76  ARG C CG  1 
ATOM   4559  C  CD  . ARG C 1 76  ? 43.227  121.487 26.314  1.00 45.89  ? 76  ARG C CD  1 
ATOM   4560  N  NE  . ARG C 1 76  ? 42.910  120.093 26.033  1.00 52.80  ? 76  ARG C NE  1 
ATOM   4561  C  CZ  . ARG C 1 76  ? 43.772  119.219 25.532  1.00 51.94  ? 76  ARG C CZ  1 
ATOM   4562  N  NH1 . ARG C 1 76  ? 45.024  119.559 25.262  1.00 53.04  ? 76  ARG C NH1 1 
ATOM   4563  N  NH2 . ARG C 1 76  ? 43.369  117.973 25.298  1.00 51.55  ? 76  ARG C NH2 1 
ATOM   4564  N  N   . ILE C 1 77  ? 41.340  120.529 31.346  1.00 47.56  ? 77  ILE C N   1 
ATOM   4565  C  CA  . ILE C 1 77  ? 40.421  119.837 32.245  1.00 45.56  ? 77  ILE C CA  1 
ATOM   4566  C  C   . ILE C 1 77  ? 39.952  118.514 31.646  1.00 46.12  ? 77  ILE C C   1 
ATOM   4567  O  O   . ILE C 1 77  ? 39.658  117.565 32.383  1.00 49.04  ? 77  ILE C O   1 
ATOM   4568  C  CB  . ILE C 1 77  ? 39.223  120.740 32.608  1.00 49.72  ? 77  ILE C CB  1 
ATOM   4569  C  CG1 . ILE C 1 77  ? 39.670  122.033 33.317  1.00 54.28  ? 77  ILE C CG1 1 
ATOM   4570  C  CG2 . ILE C 1 77  ? 38.187  119.959 33.428  1.00 42.87  ? 77  ILE C CG2 1 
ATOM   4571  C  CD1 . ILE C 1 77  ? 40.346  123.126 32.429  1.00 47.62  ? 77  ILE C CD1 1 
ATOM   4572  N  N   . GLU C 1 78  ? 39.885  118.417 30.319  1.00 43.24  ? 78  GLU C N   1 
ATOM   4573  C  CA  . GLU C 1 78  ? 39.421  117.196 29.671  1.00 45.84  ? 78  GLU C CA  1 
ATOM   4574  C  C   . GLU C 1 78  ? 40.496  116.116 29.609  1.00 45.12  ? 78  GLU C C   1 
ATOM   4575  O  O   . GLU C 1 78  ? 40.196  114.981 29.212  1.00 37.00  ? 78  GLU C O   1 
ATOM   4576  C  CB  . GLU C 1 78  ? 38.917  117.504 28.256  1.00 45.49  ? 78  GLU C CB  1 
ATOM   4577  C  CG  . GLU C 1 78  ? 40.014  117.907 27.273  1.00 50.11  ? 78  GLU C CG  1 
ATOM   4578  C  CD  . GLU C 1 78  ? 39.900  119.348 26.791  1.00 58.90  ? 78  GLU C CD  1 
ATOM   4579  O  OE1 . GLU C 1 78  ? 39.470  120.230 27.580  1.00 55.88  ? 78  GLU C OE1 1 
ATOM   4580  O  OE2 . GLU C 1 78  ? 40.268  119.599 25.621  1.00 57.13  ? 78  GLU C OE2 1 
ATOM   4581  N  N   . GLU C 1 79  ? 41.739  116.446 29.972  1.00 44.65  ? 79  GLU C N   1 
ATOM   4582  C  CA  . GLU C 1 79  ? 42.788  115.446 30.112  1.00 41.20  ? 79  GLU C CA  1 
ATOM   4583  C  C   . GLU C 1 79  ? 42.750  114.724 31.457  1.00 36.95  ? 79  GLU C C   1 
ATOM   4584  O  O   . GLU C 1 79  ? 43.515  113.771 31.647  1.00 34.58  ? 79  GLU C O   1 
ATOM   4585  C  CB  . GLU C 1 79  ? 44.159  116.093 29.916  1.00 36.17  ? 79  GLU C CB  1 
ATOM   4586  C  CG  . GLU C 1 79  ? 44.380  116.624 28.516  1.00 41.38  ? 79  GLU C CG  1 
ATOM   4587  C  CD  . GLU C 1 79  ? 45.775  117.173 28.323  1.00 40.41  ? 79  GLU C CD  1 
ATOM   4588  O  OE1 . GLU C 1 79  ? 46.003  118.350 28.683  1.00 38.46  ? 79  GLU C OE1 1 
ATOM   4589  O  OE2 . GLU C 1 79  ? 46.645  116.423 27.822  1.00 39.69  ? 79  GLU C OE2 1 
ATOM   4590  N  N   . GLY C 1 80  ? 41.897  115.147 32.386  1.00 33.60  ? 80  GLY C N   1 
ATOM   4591  C  CA  . GLY C 1 80  ? 41.794  114.436 33.651  1.00 35.21  ? 80  GLY C CA  1 
ATOM   4592  C  C   . GLY C 1 80  ? 41.314  113.013 33.423  1.00 37.70  ? 80  GLY C C   1 
ATOM   4593  O  O   . GLY C 1 80  ? 40.466  112.754 32.565  1.00 34.53  ? 80  GLY C O   1 
ATOM   4594  N  N   . CYS C 1 81  ? 41.877  112.073 34.187  1.00 33.06  ? 81  CYS C N   1 
ATOM   4595  C  CA  . CYS C 1 81  ? 41.668  110.672 33.833  1.00 34.60  ? 81  CYS C CA  1 
ATOM   4596  C  C   . CYS C 1 81  ? 40.194  110.270 33.929  1.00 33.43  ? 81  CYS C C   1 
ATOM   4597  O  O   . CYS C 1 81  ? 39.728  109.467 33.115  1.00 33.76  ? 81  CYS C O   1 
ATOM   4598  C  CB  . CYS C 1 81  ? 42.559  109.764 34.686  1.00 33.50  ? 81  CYS C CB  1 
ATOM   4599  S  SG  . CYS C 1 81  ? 42.230  109.804 36.442  1.00 28.89  ? 81  CYS C SG  1 
ATOM   4600  N  N   . VAL C 1 82  ? 39.427  110.835 34.867  1.00 31.10  ? 82  VAL C N   1 
ATOM   4601  C  CA  . VAL C 1 82  ? 37.990  110.538 34.878  1.00 35.79  ? 82  VAL C CA  1 
ATOM   4602  C  C   . VAL C 1 82  ? 37.334  111.083 33.616  1.00 38.41  ? 82  VAL C C   1 
ATOM   4603  O  O   . VAL C 1 82  ? 36.576  110.385 32.924  1.00 36.85  ? 82  VAL C O   1 
ATOM   4604  C  CB  . VAL C 1 82  ? 37.306  111.109 36.133  1.00 33.63  ? 82  VAL C CB  1 
ATOM   4605  C  CG1 . VAL C 1 82  ? 35.783  110.953 36.019  1.00 32.92  ? 82  VAL C CG1 1 
ATOM   4606  C  CG2 . VAL C 1 82  ? 37.814  110.423 37.386  1.00 30.92  ? 82  VAL C CG2 1 
ATOM   4607  N  N   . GLN C 1 83  ? 37.638  112.341 33.293  1.00 37.00  ? 83  GLN C N   1 
ATOM   4608  C  CA  . GLN C 1 83  ? 36.992  113.006 32.171  1.00 36.97  ? 83  GLN C CA  1 
ATOM   4609  C  C   . GLN C 1 83  ? 37.334  112.307 30.867  1.00 38.06  ? 83  GLN C C   1 
ATOM   4610  O  O   . GLN C 1 83  ? 36.452  112.048 30.038  1.00 41.15  ? 83  GLN C O   1 
ATOM   4611  C  CB  . GLN C 1 83  ? 37.404  114.481 32.142  1.00 34.56  ? 83  GLN C CB  1 
ATOM   4612  C  CG  . GLN C 1 83  ? 36.928  115.294 33.356  1.00 35.65  ? 83  GLN C CG  1 
ATOM   4613  C  CD  . GLN C 1 83  ? 37.676  114.985 34.674  1.00 41.33  ? 83  GLN C CD  1 
ATOM   4614  O  OE1 . GLN C 1 83  ? 38.647  114.222 34.705  1.00 37.72  ? 83  GLN C OE1 1 
ATOM   4615  N  NE2 . GLN C 1 83  ? 37.223  115.604 35.764  1.00 44.09  ? 83  GLN C NE2 1 
ATOM   4616  N  N   . ALA C 1 84  ? 38.609  111.952 30.690  1.00 33.62  ? 84  ALA C N   1 
ATOM   4617  C  CA  . ALA C 1 84  ? 39.036  111.315 29.452  1.00 37.40  ? 84  ALA C CA  1 
ATOM   4618  C  C   . ALA C 1 84  ? 38.444  109.917 29.294  1.00 38.45  ? 84  ALA C C   1 
ATOM   4619  O  O   . ALA C 1 84  ? 38.175  109.484 28.166  1.00 38.75  ? 84  ALA C O   1 
ATOM   4620  C  CB  . ALA C 1 84  ? 40.563  111.261 29.393  1.00 38.03  ? 84  ALA C CB  1 
ATOM   4621  N  N   . LEU C 1 85  ? 38.247  109.194 30.398  1.00 36.00  ? 85  LEU C N   1 
ATOM   4622  C  CA  . LEU C 1 85  ? 37.628  107.877 30.293  1.00 37.81  ? 85  LEU C CA  1 
ATOM   4623  C  C   . LEU C 1 85  ? 36.150  107.991 29.950  1.00 39.47  ? 85  LEU C C   1 
ATOM   4624  O  O   . LEU C 1 85  ? 35.640  107.207 29.142  1.00 39.72  ? 85  LEU C O   1 
ATOM   4625  C  CB  . LEU C 1 85  ? 37.813  107.082 31.587  1.00 29.13  ? 85  LEU C CB  1 
ATOM   4626  C  CG  . LEU C 1 85  ? 39.240  106.568 31.775  1.00 36.77  ? 85  LEU C CG  1 
ATOM   4627  C  CD1 . LEU C 1 85  ? 39.345  105.684 33.007  1.00 32.88  ? 85  LEU C CD1 1 
ATOM   4628  C  CD2 . LEU C 1 85  ? 39.719  105.824 30.543  1.00 33.55  ? 85  LEU C CD2 1 
ATOM   4629  N  N   . LYS C 1 86  ? 35.443  108.938 30.578  1.00 36.53  ? 86  LYS C N   1 
ATOM   4630  C  CA  . LYS C 1 86  ? 34.048  109.178 30.215  1.00 42.19  ? 86  LYS C CA  1 
ATOM   4631  C  C   . LYS C 1 86  ? 33.923  109.501 28.731  1.00 40.29  ? 86  LYS C C   1 
ATOM   4632  O  O   . LYS C 1 86  ? 33.089  108.924 28.027  1.00 42.80  ? 86  LYS C O   1 
ATOM   4633  C  CB  . LYS C 1 86  ? 33.453  110.306 31.064  1.00 38.05  ? 86  LYS C CB  1 
ATOM   4634  C  CG  . LYS C 1 86  ? 33.070  109.882 32.461  1.00 40.77  ? 86  LYS C CG  1 
ATOM   4635  C  CD  . LYS C 1 86  ? 32.292  110.977 33.176  1.00 41.12  ? 86  LYS C CD  1 
ATOM   4636  C  CE  . LYS C 1 86  ? 32.226  110.705 34.660  1.00 39.01  ? 86  LYS C CE  1 
ATOM   4637  N  NZ  . LYS C 1 86  ? 31.443  111.744 35.378  1.00 50.12  ? 86  LYS C NZ  1 
ATOM   4638  N  N   . ALA C 1 87  ? 34.769  110.401 28.235  1.00 40.80  ? 87  ALA C N   1 
ATOM   4639  C  CA  . ALA C 1 87  ? 34.823  110.655 26.800  1.00 39.67  ? 87  ALA C CA  1 
ATOM   4640  C  C   . ALA C 1 87  ? 35.088  109.374 26.021  1.00 39.39  ? 87  ALA C C   1 
ATOM   4641  O  O   . ALA C 1 87  ? 34.522  109.162 24.942  1.00 44.49  ? 87  ALA C O   1 
ATOM   4642  C  CB  . ALA C 1 87  ? 35.897  111.697 26.495  1.00 36.96  ? 87  ALA C CB  1 
ATOM   4643  N  N   . PHE C 1 88  ? 35.922  108.491 26.565  1.00 39.17  ? 88  PHE C N   1 
ATOM   4644  C  CA  . PHE C 1 88  ? 36.286  107.266 25.864  1.00 37.07  ? 88  PHE C CA  1 
ATOM   4645  C  C   . PHE C 1 88  ? 35.176  106.227 25.875  1.00 36.35  ? 88  PHE C C   1 
ATOM   4646  O  O   . PHE C 1 88  ? 35.141  105.372 24.989  1.00 40.60  ? 88  PHE C O   1 
ATOM   4647  C  CB  . PHE C 1 88  ? 37.553  106.676 26.486  1.00 43.44  ? 88  PHE C CB  1 
ATOM   4648  C  CG  . PHE C 1 88  ? 38.008  105.379 25.857  1.00 38.98  ? 88  PHE C CG  1 
ATOM   4649  C  CD1 . PHE C 1 88  ? 38.732  105.388 24.673  1.00 41.77  ? 88  PHE C CD1 1 
ATOM   4650  C  CD2 . PHE C 1 88  ? 37.737  104.165 26.466  1.00 33.09  ? 88  PHE C CD2 1 
ATOM   4651  C  CE1 . PHE C 1 88  ? 39.164  104.207 24.103  1.00 41.06  ? 88  PHE C CE1 1 
ATOM   4652  C  CE2 . PHE C 1 88  ? 38.161  102.977 25.898  1.00 37.76  ? 88  PHE C CE2 1 
ATOM   4653  C  CZ  . PHE C 1 88  ? 38.877  102.998 24.718  1.00 42.92  ? 88  PHE C CZ  1 
ATOM   4654  N  N   . GLY C 1 89  ? 34.274  106.277 26.850  1.00 38.85  ? 89  GLY C N   1 
ATOM   4655  C  CA  . GLY C 1 89  ? 33.214  105.294 26.939  1.00 37.75  ? 89  GLY C CA  1 
ATOM   4656  C  C   . GLY C 1 89  ? 33.170  104.517 28.244  1.00 39.24  ? 89  GLY C C   1 
ATOM   4657  O  O   . GLY C 1 89  ? 32.429  103.536 28.349  1.00 41.15  ? 89  GLY C O   1 
ATOM   4658  N  N   . ILE C 1 90  ? 33.940  104.931 29.248  1.00 37.37  ? 90  ILE C N   1 
ATOM   4659  C  CA  . ILE C 1 90  ? 34.090  104.162 30.479  1.00 34.08  ? 90  ILE C CA  1 
ATOM   4660  C  C   . ILE C 1 90  ? 33.779  105.082 31.645  1.00 34.80  ? 90  ILE C C   1 
ATOM   4661  O  O   . ILE C 1 90  ? 34.489  106.073 31.866  1.00 37.96  ? 90  ILE C O   1 
ATOM   4662  C  CB  . ILE C 1 90  ? 35.499  103.558 30.622  1.00 34.63  ? 90  ILE C CB  1 
ATOM   4663  C  CG1 . ILE C 1 90  ? 35.708  102.451 29.583  1.00 35.93  ? 90  ILE C CG1 1 
ATOM   4664  C  CG2 . ILE C 1 90  ? 35.718  103.019 32.040  1.00 32.91  ? 90  ILE C CG2 1 
ATOM   4665  C  CD1 . ILE C 1 90  ? 37.182  102.087 29.355  1.00 32.68  ? 90  ILE C CD1 1 
ATOM   4666  N  N   . GLU C 1 91  ? 32.712  104.763 32.380  1.00 35.21  ? 91  GLU C N   1 
ATOM   4667  C  CA  . GLU C 1 91  ? 32.283  105.540 33.525  1.00 33.07  ? 91  GLU C CA  1 
ATOM   4668  C  C   . GLU C 1 91  ? 33.085  105.122 34.754  1.00 35.64  ? 91  GLU C C   1 
ATOM   4669  O  O   . GLU C 1 91  ? 33.485  103.960 34.867  1.00 32.59  ? 91  GLU C O   1 
ATOM   4670  C  CB  . GLU C 1 91  ? 30.788  105.334 33.778  1.00 40.90  ? 91  GLU C CB  1 
ATOM   4671  C  CG  . GLU C 1 91  ? 29.851  105.992 32.747  1.00 37.45  ? 91  GLU C CG  1 
ATOM   4672  C  CD  . GLU C 1 91  ? 29.975  107.504 32.731  1.00 41.26  ? 91  GLU C CD  1 
ATOM   4673  O  OE1 . GLU C 1 91  ? 29.742  108.145 33.781  1.00 42.65  ? 91  GLU C OE1 1 
ATOM   4674  O  OE2 . GLU C 1 91  ? 30.317  108.049 31.665  1.00 44.44  ? 91  GLU C OE2 1 
ATOM   4675  N  N   . PRO C 1 92  ? 33.314  106.046 35.695  1.00 38.88  ? 92  PRO C N   1 
ATOM   4676  C  CA  . PRO C 1 92  ? 34.254  105.751 36.799  1.00 35.15  ? 92  PRO C CA  1 
ATOM   4677  C  C   . PRO C 1 92  ? 33.888  104.513 37.609  1.00 35.70  ? 92  PRO C C   1 
ATOM   4678  O  O   . PRO C 1 92  ? 34.774  103.874 38.192  1.00 30.48  ? 92  PRO C O   1 
ATOM   4679  C  CB  . PRO C 1 92  ? 34.213  107.014 37.674  1.00 31.10  ? 92  PRO C CB  1 
ATOM   4680  C  CG  . PRO C 1 92  ? 33.157  107.906 37.110  1.00 37.15  ? 92  PRO C CG  1 
ATOM   4681  C  CD  . PRO C 1 92  ? 32.647  107.356 35.821  1.00 34.31  ? 92  PRO C CD  1 
ATOM   4682  N  N   . ALA C 1 93  ? 32.609  104.147 37.669  1.00 34.40  ? 93  ALA C N   1 
ATOM   4683  C  CA  . ALA C 1 93  ? 32.254  102.941 38.402  1.00 33.94  ? 93  ALA C CA  1 
ATOM   4684  C  C   . ALA C 1 93  ? 32.693  101.678 37.679  1.00 30.83  ? 93  ALA C C   1 
ATOM   4685  O  O   . ALA C 1 93  ? 32.685  100.605 38.293  1.00 31.40  ? 93  ALA C O   1 
ATOM   4686  C  CB  . ALA C 1 93  ? 30.743  102.883 38.659  1.00 29.73  ? 93  ALA C CB  1 
ATOM   4687  N  N   . ASP C 1 94  ? 33.084  101.783 36.409  1.00 33.34  ? 94  ASP C N   1 
ATOM   4688  C  CA  . ASP C 1 94  ? 33.438  100.638 35.571  1.00 31.38  ? 94  ASP C CA  1 
ATOM   4689  C  C   . ASP C 1 94  ? 34.949  100.413 35.532  1.00 33.53  ? 94  ASP C C   1 
ATOM   4690  O  O   . ASP C 1 94  ? 35.534  100.125 34.479  1.00 34.55  ? 94  ASP C O   1 
ATOM   4691  C  CB  . ASP C 1 94  ? 32.878  100.827 34.166  1.00 34.60  ? 94  ASP C CB  1 
ATOM   4692  C  CG  . ASP C 1 94  ? 32.832  99.522  33.371  1.00 46.38  ? 94  ASP C CG  1 
ATOM   4693  O  OD1 . ASP C 1 94  ? 32.815  98.436  33.994  1.00 53.48  ? 94  ASP C OD1 1 
ATOM   4694  O  OD2 . ASP C 1 94  ? 32.810  99.578  32.122  1.00 48.16  ? 94  ASP C OD2 1 
ATOM   4695  N  N   . VAL C 1 95  ? 35.606  100.555 36.679  1.00 31.15  ? 95  VAL C N   1 
ATOM   4696  C  CA  . VAL C 1 95  ? 37.057  100.451 36.806  1.00 26.67  ? 95  VAL C CA  1 
ATOM   4697  C  C   . VAL C 1 95  ? 37.287  99.515  37.981  1.00 25.75  ? 95  VAL C C   1 
ATOM   4698  O  O   . VAL C 1 95  ? 36.952  99.858  39.121  1.00 28.31  ? 95  VAL C O   1 
ATOM   4699  C  CB  . VAL C 1 95  ? 37.720  101.819 37.058  1.00 28.33  ? 95  VAL C CB  1 
ATOM   4700  C  CG1 . VAL C 1 95  ? 39.224  101.670 37.353  1.00 25.98  ? 95  VAL C CG1 1 
ATOM   4701  C  CG2 . VAL C 1 95  ? 37.486  102.764 35.883  1.00 29.34  ? 95  VAL C CG2 1 
ATOM   4702  N  N   . ARG C 1 96  ? 37.843  98.338  37.715  1.00 22.89  ? 96  ARG C N   1 
ATOM   4703  C  CA  . ARG C 1 96  ? 38.004  97.370  38.791  1.00 22.81  ? 96  ARG C CA  1 
ATOM   4704  C  C   . ARG C 1 96  ? 39.285  97.603  39.599  1.00 24.65  ? 96  ARG C C   1 
ATOM   4705  O  O   . ARG C 1 96  ? 39.292  97.405  40.810  1.00 28.17  ? 96  ARG C O   1 
ATOM   4706  C  CB  . ARG C 1 96  ? 37.977  95.953  38.209  1.00 23.90  ? 96  ARG C CB  1 
ATOM   4707  C  CG  . ARG C 1 96  ? 37.917  94.860  39.273  1.00 26.96  ? 96  ARG C CG  1 
ATOM   4708  C  CD  . ARG C 1 96  ? 37.881  93.505  38.632  1.00 26.14  ? 96  ARG C CD  1 
ATOM   4709  N  NE  . ARG C 1 96  ? 38.006  92.426  39.601  1.00 30.86  ? 96  ARG C NE  1 
ATOM   4710  C  CZ  . ARG C 1 96  ? 37.938  91.139  39.280  1.00 32.26  ? 96  ARG C CZ  1 
ATOM   4711  N  NH1 . ARG C 1 96  ? 37.740  90.748  38.032  1.00 30.24  ? 96  ARG C NH1 1 
ATOM   4712  N  NH2 . ARG C 1 96  ? 38.088  90.225  40.230  1.00 25.07  ? 96  ARG C NH2 1 
ATOM   4713  N  N   . TYR C 1 97  ? 40.384  97.992  38.963  1.00 24.18  ? 97  TYR C N   1 
ATOM   4714  C  CA  . TYR C 1 97  ? 41.653  98.141  39.659  1.00 22.32  ? 97  TYR C CA  1 
ATOM   4715  C  C   . TYR C 1 97  ? 42.282  99.459  39.252  1.00 26.88  ? 97  TYR C C   1 
ATOM   4716  O  O   . TYR C 1 97  ? 42.219  99.846  38.078  1.00 23.29  ? 97  TYR C O   1 
ATOM   4717  C  CB  . TYR C 1 97  ? 42.643  97.006  39.336  1.00 20.96  ? 97  TYR C CB  1 
ATOM   4718  C  CG  . TYR C 1 97  ? 42.179  95.623  39.737  1.00 22.61  ? 97  TYR C CG  1 
ATOM   4719  C  CD1 . TYR C 1 97  ? 42.067  95.258  41.076  1.00 21.93  ? 97  TYR C CD1 1 
ATOM   4720  C  CD2 . TYR C 1 97  ? 41.837  94.683  38.778  1.00 23.54  ? 97  TYR C CD2 1 
ATOM   4721  C  CE1 . TYR C 1 97  ? 41.651  93.971  41.438  1.00 24.31  ? 97  TYR C CE1 1 
ATOM   4722  C  CE2 . TYR C 1 97  ? 41.409  93.415  39.130  1.00 20.86  ? 97  TYR C CE2 1 
ATOM   4723  C  CZ  . TYR C 1 97  ? 41.313  93.060  40.455  1.00 25.64  ? 97  TYR C CZ  1 
ATOM   4724  O  OH  . TYR C 1 97  ? 40.883  91.780  40.790  1.00 23.91  ? 97  TYR C OH  1 
ATOM   4725  N  N   . VAL C 1 98  ? 42.873  100.147 40.229  1.00 24.79  ? 98  VAL C N   1 
ATOM   4726  C  CA  . VAL C 1 98  ? 43.855  101.194 39.976  1.00 25.57  ? 98  VAL C CA  1 
ATOM   4727  C  C   . VAL C 1 98  ? 45.204  100.687 40.482  1.00 24.48  ? 98  VAL C C   1 
ATOM   4728  O  O   . VAL C 1 98  ? 45.340  100.321 41.658  1.00 23.48  ? 98  VAL C O   1 
ATOM   4729  C  CB  . VAL C 1 98  ? 43.461  102.522 40.645  1.00 27.44  ? 98  VAL C CB  1 
ATOM   4730  C  CG1 . VAL C 1 98  ? 44.557  103.530 40.506  1.00 19.18  ? 98  VAL C CG1 1 
ATOM   4731  C  CG2 . VAL C 1 98  ? 42.184  103.057 40.037  1.00 26.87  ? 98  VAL C CG2 1 
ATOM   4732  N  N   . LEU C 1 99  ? 46.189  100.642 39.592  1.00 23.80  ? 99  LEU C N   1 
ATOM   4733  C  CA  . LEU C 1 99  ? 47.557  100.256 39.919  1.00 21.13  ? 99  LEU C CA  1 
ATOM   4734  C  C   . LEU C 1 99  ? 48.411  101.504 40.043  1.00 22.41  ? 99  LEU C C   1 
ATOM   4735  O  O   . LEU C 1 99  ? 48.293  102.416 39.218  1.00 20.87  ? 99  LEU C O   1 
ATOM   4736  C  CB  . LEU C 1 99  ? 48.150  99.369  38.826  1.00 19.52  ? 99  LEU C CB  1 
ATOM   4737  C  CG  . LEU C 1 99  ? 47.289  98.222  38.333  1.00 20.19  ? 99  LEU C CG  1 
ATOM   4738  C  CD1 . LEU C 1 99  ? 48.066  97.370  37.326  1.00 18.89  ? 99  LEU C CD1 1 
ATOM   4739  C  CD2 . LEU C 1 99  ? 46.820  97.376  39.515  1.00 17.42  ? 99  LEU C CD2 1 
ATOM   4740  N  N   . HIS C 1 100 ? 49.307  101.537 41.037  1.00 18.91  ? 100 HIS C N   1 
ATOM   4741  C  CA  . HIS C 1 100 ? 50.229  102.662 41.165  1.00 18.69  ? 100 HIS C CA  1 
ATOM   4742  C  C   . HIS C 1 100 ? 51.669  102.190 41.014  1.00 22.08  ? 100 HIS C C   1 
ATOM   4743  O  O   . HIS C 1 100 ? 52.137  101.332 41.779  1.00 18.26  ? 100 HIS C O   1 
ATOM   4744  C  CB  . HIS C 1 100 ? 50.034  103.411 42.488  1.00 18.10  ? 100 HIS C CB  1 
ATOM   4745  C  CG  . HIS C 1 100 ? 48.865  104.351 42.467  1.00 20.89  ? 100 HIS C CG  1 
ATOM   4746  N  ND1 . HIS C 1 100 ? 48.773  105.411 41.582  1.00 18.74  ? 100 HIS C ND1 1 
ATOM   4747  C  CD2 . HIS C 1 100 ? 47.729  104.379 43.204  1.00 18.89  ? 100 HIS C CD2 1 
ATOM   4748  C  CE1 . HIS C 1 100 ? 47.631  106.045 41.778  1.00 19.80  ? 100 HIS C CE1 1 
ATOM   4749  N  NE2 . HIS C 1 100 ? 46.985  105.448 42.763  1.00 17.59  ? 100 HIS C NE2 1 
ATOM   4750  N  N   . SER C 1 101 ? 52.370  102.767 40.021  1.00 20.23  ? 101 SER C N   1 
ATOM   4751  C  CA  . SER C 1 101 ? 53.821  102.642 39.968  1.00 20.26  ? 101 SER C CA  1 
ATOM   4752  C  C   . SER C 1 101 ? 54.439  103.154 41.260  1.00 17.91  ? 101 SER C C   1 
ATOM   4753  O  O   . SER C 1 101 ? 55.337  102.523 41.829  1.00 19.97  ? 101 SER C O   1 
ATOM   4754  C  CB  . SER C 1 101 ? 54.379  103.415 38.756  1.00 23.27  ? 101 SER C CB  1 
ATOM   4755  O  OG  . SER C 1 101 ? 54.206  104.816 38.919  1.00 25.77  ? 101 SER C OG  1 
ATOM   4756  N  N   . HIS C 1 102 ? 53.944  104.287 41.742  1.00 22.35  ? 102 HIS C N   1 
ATOM   4757  C  CA  . HIS C 1 102 ? 54.396  104.956 42.956  1.00 21.01  ? 102 HIS C CA  1 
ATOM   4758  C  C   . HIS C 1 102 ? 53.460  106.132 43.157  1.00 23.38  ? 102 HIS C C   1 
ATOM   4759  O  O   . HIS C 1 102 ? 52.529  106.336 42.374  1.00 25.33  ? 102 HIS C O   1 
ATOM   4760  C  CB  . HIS C 1 102 ? 55.857  105.397 42.880  1.00 21.82  ? 102 HIS C CB  1 
ATOM   4761  C  CG  . HIS C 1 102 ? 56.158  106.355 41.769  1.00 23.29  ? 102 HIS C CG  1 
ATOM   4762  N  ND1 . HIS C 1 102 ? 55.726  106.166 40.472  1.00 30.73  ? 102 HIS C ND1 1 
ATOM   4763  C  CD2 . HIS C 1 102 ? 56.887  107.497 41.759  1.00 25.05  ? 102 HIS C CD2 1 
ATOM   4764  C  CE1 . HIS C 1 102 ? 56.183  107.146 39.709  1.00 25.73  ? 102 HIS C CE1 1 
ATOM   4765  N  NE2 . HIS C 1 102 ? 56.886  107.968 40.469  1.00 28.26  ? 102 HIS C NE2 1 
ATOM   4766  N  N   . LEU C 1 103 ? 53.703  106.912 44.208  1.00 20.35  ? 103 LEU C N   1 
ATOM   4767  C  CA  . LEU C 1 103 ? 52.694  107.883 44.613  1.00 19.47  ? 103 LEU C CA  1 
ATOM   4768  C  C   . LEU C 1 103 ? 53.163  109.327 44.478  1.00 24.48  ? 103 LEU C C   1 
ATOM   4769  O  O   . LEU C 1 103 ? 52.601  110.210 45.129  1.00 27.03  ? 103 LEU C O   1 
ATOM   4770  C  CB  . LEU C 1 103 ? 52.218  107.596 46.031  1.00 16.33  ? 103 LEU C CB  1 
ATOM   4771  C  CG  . LEU C 1 103 ? 51.527  106.237 46.220  1.00 22.59  ? 103 LEU C CG  1 
ATOM   4772  C  CD1 . LEU C 1 103 ? 51.246  105.952 47.713  1.00 20.70  ? 103 LEU C CD1 1 
ATOM   4773  C  CD2 . LEU C 1 103 ? 50.239  106.125 45.407  1.00 19.22  ? 103 LEU C CD2 1 
ATOM   4774  N  N   . HIS C 1 104 ? 54.162  109.590 43.634  1.00 21.05  ? 104 HIS C N   1 
ATOM   4775  C  CA  . HIS C 1 104 ? 54.487  110.963 43.287  1.00 23.81  ? 104 HIS C CA  1 
ATOM   4776  C  C   . HIS C 1 104 ? 53.293  111.668 42.641  1.00 28.78  ? 104 HIS C C   1 
ATOM   4777  O  O   . HIS C 1 104 ? 52.356  111.045 42.118  1.00 25.25  ? 104 HIS C O   1 
ATOM   4778  C  CB  . HIS C 1 104 ? 55.680  111.024 42.333  1.00 26.45  ? 104 HIS C CB  1 
ATOM   4779  C  CG  . HIS C 1 104 ? 56.983  110.707 42.992  1.00 26.91  ? 104 HIS C CG  1 
ATOM   4780  N  ND1 . HIS C 1 104 ? 58.144  110.486 42.285  1.00 23.35  ? 104 HIS C ND1 1 
ATOM   4781  C  CD2 . HIS C 1 104 ? 57.297  110.531 44.299  1.00 25.49  ? 104 HIS C CD2 1 
ATOM   4782  C  CE1 . HIS C 1 104 ? 59.123  110.208 43.127  1.00 24.41  ? 104 HIS C CE1 1 
ATOM   4783  N  NE2 . HIS C 1 104 ? 58.634  110.227 44.356  1.00 27.34  ? 104 HIS C NE2 1 
ATOM   4784  N  N   . LEU C 1 105 ? 53.399  112.995 42.630  1.00 28.14  ? 105 LEU C N   1 
ATOM   4785  C  CA  . LEU C 1 105 ? 52.303  113.901 42.294  1.00 25.89  ? 105 LEU C CA  1 
ATOM   4786  C  C   . LEU C 1 105 ? 51.774  113.717 40.880  1.00 27.17  ? 105 LEU C C   1 
ATOM   4787  O  O   . LEU C 1 105 ? 50.577  113.936 40.647  1.00 29.22  ? 105 LEU C O   1 
ATOM   4788  C  CB  . LEU C 1 105 ? 52.765  115.347 42.491  1.00 27.67  ? 105 LEU C CB  1 
ATOM   4789  C  CG  . LEU C 1 105 ? 53.769  115.956 41.506  1.00 27.86  ? 105 LEU C CG  1 
ATOM   4790  C  CD1 . LEU C 1 105 ? 54.041  117.408 41.910  1.00 32.08  ? 105 LEU C CD1 1 
ATOM   4791  C  CD2 . LEU C 1 105 ? 55.074  115.201 41.456  1.00 27.41  ? 105 LEU C CD2 1 
ATOM   4792  N  N   . ASP C 1 106 ? 52.625  113.358 39.914  1.00 25.42  ? 106 ASP C N   1 
ATOM   4793  C  CA  . ASP C 1 106 ? 52.146  113.118 38.557  1.00 24.12  ? 106 ASP C CA  1 
ATOM   4794  C  C   . ASP C 1 106 ? 51.695  111.668 38.331  1.00 29.67  ? 106 ASP C C   1 
ATOM   4795  O  O   . ASP C 1 106 ? 51.619  111.215 37.172  1.00 25.34  ? 106 ASP C O   1 
ATOM   4796  C  CB  . ASP C 1 106 ? 53.215  113.509 37.532  1.00 29.16  ? 106 ASP C CB  1 
ATOM   4797  C  CG  . ASP C 1 106 ? 54.568  112.918 37.847  1.00 31.48  ? 106 ASP C CG  1 
ATOM   4798  O  OD1 . ASP C 1 106 ? 54.974  112.908 39.035  1.00 26.82  ? 106 ASP C OD1 1 
ATOM   4799  O  OD2 . ASP C 1 106 ? 55.230  112.478 36.891  1.00 33.52  ? 106 ASP C OD2 1 
ATOM   4800  N  N   . HIS C 1 107 ? 51.387  110.939 39.417  1.00 23.48  ? 107 HIS C N   1 
ATOM   4801  C  CA  . HIS C 1 107 ? 50.954  109.554 39.309  1.00 26.96  ? 107 HIS C CA  1 
ATOM   4802  C  C   . HIS C 1 107 ? 49.823  109.199 40.266  1.00 23.04  ? 107 HIS C C   1 
ATOM   4803  O  O   . HIS C 1 107 ? 49.551  108.015 40.459  1.00 25.86  ? 107 HIS C O   1 
ATOM   4804  C  CB  . HIS C 1 107 ? 52.132  108.603 39.541  1.00 25.10  ? 107 HIS C CB  1 
ATOM   4805  C  CG  . HIS C 1 107 ? 53.237  108.771 38.558  1.00 26.28  ? 107 HIS C CG  1 
ATOM   4806  N  ND1 . HIS C 1 107 ? 53.299  108.047 37.385  1.00 29.21  ? 107 HIS C ND1 1 
ATOM   4807  C  CD2 . HIS C 1 107 ? 54.327  109.577 38.564  1.00 27.70  ? 107 HIS C CD2 1 
ATOM   4808  C  CE1 . HIS C 1 107 ? 54.381  108.400 36.710  1.00 29.03  ? 107 HIS C CE1 1 
ATOM   4809  N  NE2 . HIS C 1 107 ? 55.016  109.329 37.400  1.00 29.77  ? 107 HIS C NE2 1 
ATOM   4810  N  N   . THR C 1 108 ? 49.160  110.177 40.870  1.00 25.50  ? 108 THR C N   1 
ATOM   4811  C  CA  . THR C 1 108 ? 48.077  109.921 41.811  1.00 23.08  ? 108 THR C CA  1 
ATOM   4812  C  C   . THR C 1 108 ? 46.788  110.623 41.389  1.00 25.87  ? 108 THR C C   1 
ATOM   4813  O  O   . THR C 1 108 ? 45.887  110.814 42.213  1.00 29.24  ? 108 THR C O   1 
ATOM   4814  C  CB  . THR C 1 108 ? 48.499  110.349 43.224  1.00 25.76  ? 108 THR C CB  1 
ATOM   4815  O  OG1 . THR C 1 108 ? 48.973  111.703 43.217  1.00 29.20  ? 108 THR C OG1 1 
ATOM   4816  C  CG2 . THR C 1 108 ? 49.647  109.484 43.721  1.00 22.47  ? 108 THR C CG2 1 
ATOM   4817  N  N   . GLY C 1 109 ? 46.684  111.026 40.115  1.00 28.36  ? 109 GLY C N   1 
ATOM   4818  C  CA  . GLY C 1 109 ? 45.446  111.620 39.635  1.00 29.56  ? 109 GLY C CA  1 
ATOM   4819  C  C   . GLY C 1 109 ? 44.259  110.673 39.693  1.00 28.34  ? 109 GLY C C   1 
ATOM   4820  O  O   . GLY C 1 109 ? 43.112  111.111 39.820  1.00 31.24  ? 109 GLY C O   1 
ATOM   4821  N  N   . ALA C 1 110 ? 44.511  109.367 39.635  1.00 29.01  ? 110 ALA C N   1 
ATOM   4822  C  CA  . ALA C 1 110 ? 43.416  108.408 39.666  1.00 27.55  ? 110 ALA C CA  1 
ATOM   4823  C  C   . ALA C 1 110 ? 42.991  108.023 41.075  1.00 30.21  ? 110 ALA C C   1 
ATOM   4824  O  O   . ALA C 1 110 ? 41.853  107.576 41.256  1.00 31.53  ? 110 ALA C O   1 
ATOM   4825  C  CB  . ALA C 1 110 ? 43.791  107.149 38.879  1.00 26.87  ? 110 ALA C CB  1 
ATOM   4826  N  N   . THR C 1 111 ? 43.846  108.223 42.077  1.00 27.73  ? 111 THR C N   1 
ATOM   4827  C  CA  . THR C 1 111 ? 43.591  107.670 43.402  1.00 25.79  ? 111 THR C CA  1 
ATOM   4828  C  C   . THR C 1 111 ? 42.261  108.147 43.961  1.00 31.40  ? 111 THR C C   1 
ATOM   4829  O  O   . THR C 1 111 ? 42.026  109.352 44.101  1.00 34.30  ? 111 THR C O   1 
ATOM   4830  C  CB  . THR C 1 111 ? 44.720  108.039 44.362  1.00 26.27  ? 111 THR C CB  1 
ATOM   4831  O  OG1 . THR C 1 111 ? 45.983  107.742 43.756  1.00 25.90  ? 111 THR C OG1 1 
ATOM   4832  C  CG2 . THR C 1 111 ? 44.585  107.244 45.644  1.00 28.93  ? 111 THR C CG2 1 
ATOM   4833  N  N   . GLY C 1 112 ? 41.398  107.195 44.303  1.00 28.58  ? 112 GLY C N   1 
ATOM   4834  C  CA  . GLY C 1 112 ? 40.121  107.517 44.894  1.00 28.37  ? 112 GLY C CA  1 
ATOM   4835  C  C   . GLY C 1 112 ? 39.101  108.095 43.940  1.00 33.13  ? 112 GLY C C   1 
ATOM   4836  O  O   . GLY C 1 112 ? 37.993  108.422 44.373  1.00 31.43  ? 112 GLY C O   1 
ATOM   4837  N  N   . ARG C 1 113 ? 39.427  108.255 42.660  1.00 28.48  ? 113 ARG C N   1 
ATOM   4838  C  CA  . ARG C 1 113 ? 38.426  108.749 41.721  1.00 35.36  ? 113 ARG C CA  1 
ATOM   4839  C  C   . ARG C 1 113 ? 37.588  107.628 41.125  1.00 33.80  ? 113 ARG C C   1 
ATOM   4840  O  O   . ARG C 1 113 ? 36.689  107.906 40.326  1.00 33.72  ? 113 ARG C O   1 
ATOM   4841  C  CB  . ARG C 1 113 ? 39.044  109.543 40.560  1.00 28.85  ? 113 ARG C CB  1 
ATOM   4842  C  CG  . ARG C 1 113 ? 40.147  110.566 40.816  1.00 33.85  ? 113 ARG C CG  1 
ATOM   4843  C  CD  . ARG C 1 113 ? 40.209  111.272 42.141  1.00 33.92  ? 113 ARG C CD  1 
ATOM   4844  N  NE  . ARG C 1 113 ? 40.972  112.505 41.967  1.00 34.91  ? 113 ARG C NE  1 
ATOM   4845  C  CZ  . ARG C 1 113 ? 42.220  112.698 42.378  1.00 37.76  ? 113 ARG C CZ  1 
ATOM   4846  N  NH1 . ARG C 1 113 ? 42.904  111.747 43.007  1.00 32.13  ? 113 ARG C NH1 1 
ATOM   4847  N  NH2 . ARG C 1 113 ? 42.799  113.878 42.154  1.00 33.91  ? 113 ARG C NH2 1 
ATOM   4848  N  N   . PHE C 1 114 ? 37.870  106.374 41.461  1.00 29.70  ? 114 PHE C N   1 
ATOM   4849  C  CA  . PHE C 1 114 ? 37.110  105.247 40.928  1.00 28.83  ? 114 PHE C CA  1 
ATOM   4850  C  C   . PHE C 1 114 ? 36.518  104.471 42.094  1.00 28.81  ? 114 PHE C C   1 
ATOM   4851  O  O   . PHE C 1 114 ? 37.233  103.713 42.775  1.00 31.76  ? 114 PHE C O   1 
ATOM   4852  C  CB  . PHE C 1 114 ? 38.008  104.399 40.026  1.00 26.30  ? 114 PHE C CB  1 
ATOM   4853  C  CG  . PHE C 1 114 ? 38.604  105.211 38.911  1.00 27.85  ? 114 PHE C CG  1 
ATOM   4854  C  CD1 . PHE C 1 114 ? 37.806  105.620 37.847  1.00 25.66  ? 114 PHE C CD1 1 
ATOM   4855  C  CD2 . PHE C 1 114 ? 39.916  105.666 38.978  1.00 28.64  ? 114 PHE C CD2 1 
ATOM   4856  C  CE1 . PHE C 1 114 ? 38.314  106.418 36.826  1.00 31.46  ? 114 PHE C CE1 1 
ATOM   4857  C  CE2 . PHE C 1 114 ? 40.449  106.473 37.963  1.00 30.34  ? 114 PHE C CE2 1 
ATOM   4858  C  CZ  . PHE C 1 114 ? 39.647  106.849 36.878  1.00 31.91  ? 114 PHE C CZ  1 
ATOM   4859  N  N   . PRO C 1 115 ? 35.216  104.639 42.365  1.00 32.93  ? 115 PRO C N   1 
ATOM   4860  C  CA  . PRO C 1 115 ? 34.668  104.234 43.678  1.00 29.03  ? 115 PRO C CA  1 
ATOM   4861  C  C   . PRO C 1 115 ? 34.660  102.737 43.936  1.00 30.48  ? 115 PRO C C   1 
ATOM   4862  O  O   . PRO C 1 115 ? 34.600  102.343 45.102  1.00 32.47  ? 115 PRO C O   1 
ATOM   4863  C  CB  . PRO C 1 115 ? 33.238  104.799 43.657  1.00 32.33  ? 115 PRO C CB  1 
ATOM   4864  C  CG  . PRO C 1 115 ? 32.886  104.955 42.186  1.00 30.81  ? 115 PRO C CG  1 
ATOM   4865  C  CD  . PRO C 1 115 ? 34.207  105.286 41.500  1.00 32.79  ? 115 PRO C CD  1 
ATOM   4866  N  N   . ASN C 1 116 ? 34.707  101.884 42.915  1.00 27.85  ? 116 ASN C N   1 
ATOM   4867  C  CA  . ASN C 1 116 ? 34.683  100.445 43.140  1.00 29.43  ? 116 ASN C CA  1 
ATOM   4868  C  C   . ASN C 1 116 ? 36.044  99.785  42.944  1.00 33.60  ? 116 ASN C C   1 
ATOM   4869  O  O   . ASN C 1 116 ? 36.136  98.555  43.007  1.00 35.31  ? 116 ASN C O   1 
ATOM   4870  C  CB  . ASN C 1 116 ? 33.672  99.765  42.214  1.00 33.59  ? 116 ASN C CB  1 
ATOM   4871  C  CG  . ASN C 1 116 ? 32.304  100.391 42.279  1.00 32.54  ? 116 ASN C CG  1 
ATOM   4872  O  OD1 . ASN C 1 116 ? 31.764  100.644 43.359  1.00 31.89  ? 116 ASN C OD1 1 
ATOM   4873  N  ND2 . ASN C 1 116 ? 31.732  100.647 41.109  1.00 30.94  ? 116 ASN C ND2 1 
ATOM   4874  N  N   . ALA C 1 117 ? 37.093  100.562 42.702  1.00 27.16  ? 117 ALA C N   1 
ATOM   4875  C  CA  . ALA C 1 117 ? 38.370  100.009 42.276  1.00 29.56  ? 117 ALA C CA  1 
ATOM   4876  C  C   . ALA C 1 117 ? 39.251  99.687  43.476  1.00 26.87  ? 117 ALA C C   1 
ATOM   4877  O  O   . ALA C 1 117 ? 39.389  100.500 44.394  1.00 24.77  ? 117 ALA C O   1 
ATOM   4878  C  CB  . ALA C 1 117 ? 39.093  100.986 41.350  1.00 24.04  ? 117 ALA C CB  1 
ATOM   4879  N  N   . ILE C 1 118 ? 39.852  98.512  43.466  1.00 25.19  ? 118 ILE C N   1 
ATOM   4880  C  CA  . ILE C 1 118 ? 40.912  98.226  44.424  1.00 27.33  ? 118 ILE C CA  1 
ATOM   4881  C  C   . ILE C 1 118 ? 42.209  98.889  43.955  1.00 27.77  ? 118 ILE C C   1 
ATOM   4882  O  O   . ILE C 1 118 ? 42.599  98.779  42.783  1.00 25.34  ? 118 ILE C O   1 
ATOM   4883  C  CB  . ILE C 1 118 ? 41.070  96.712  44.617  1.00 26.72  ? 118 ILE C CB  1 
ATOM   4884  C  CG1 . ILE C 1 118 ? 39.878  96.188  45.444  1.00 29.75  ? 118 ILE C CG1 1 
ATOM   4885  C  CG2 . ILE C 1 118 ? 42.396  96.389  45.293  1.00 24.26  ? 118 ILE C CG2 1 
ATOM   4886  C  CD1 . ILE C 1 118 ? 39.635  94.729  45.337  1.00 25.25  ? 118 ILE C CD1 1 
ATOM   4887  N  N   . HIS C 1 119 ? 42.878  99.585  44.875  1.00 25.13  ? 119 HIS C N   1 
ATOM   4888  C  CA  . HIS C 1 119 ? 44.116  100.303 44.592  1.00 26.76  ? 119 HIS C CA  1 
ATOM   4889  C  C   . HIS C 1 119 ? 45.321  99.457  45.023  1.00 24.96  ? 119 HIS C C   1 
ATOM   4890  O  O   . HIS C 1 119 ? 45.415  99.043  46.186  1.00 24.34  ? 119 HIS C O   1 
ATOM   4891  C  CB  . HIS C 1 119 ? 44.110  101.659 45.298  1.00 25.66  ? 119 HIS C CB  1 
ATOM   4892  C  CG  . HIS C 1 119 ? 43.104  102.626 44.741  1.00 28.97  ? 119 HIS C CG  1 
ATOM   4893  N  ND1 . HIS C 1 119 ? 41.749  102.359 44.711  1.00 28.61  ? 119 HIS C ND1 1 
ATOM   4894  C  CD2 . HIS C 1 119 ? 43.260  103.850 44.180  1.00 24.47  ? 119 HIS C CD2 1 
ATOM   4895  C  CE1 . HIS C 1 119 ? 41.114  103.380 44.163  1.00 28.72  ? 119 HIS C CE1 1 
ATOM   4896  N  NE2 . HIS C 1 119 ? 42.008  104.296 43.829  1.00 30.83  ? 119 HIS C NE2 1 
ATOM   4897  N  N   . ILE C 1 120 ? 46.238  99.203  44.091  1.00 19.27  ? 120 ILE C N   1 
ATOM   4898  C  CA  . ILE C 1 120 ? 47.331  98.259  44.307  1.00 24.60  ? 120 ILE C CA  1 
ATOM   4899  C  C   . ILE C 1 120 ? 48.663  98.989  44.158  1.00 19.81  ? 120 ILE C C   1 
ATOM   4900  O  O   . ILE C 1 120 ? 48.962  99.553  43.095  1.00 19.56  ? 120 ILE C O   1 
ATOM   4901  C  CB  . ILE C 1 120 ? 47.250  97.058  43.348  1.00 22.44  ? 120 ILE C CB  1 
ATOM   4902  C  CG1 . ILE C 1 120 ? 45.844  96.443  43.358  1.00 20.70  ? 120 ILE C CG1 1 
ATOM   4903  C  CG2 . ILE C 1 120 ? 48.296  96.015  43.731  1.00 21.15  ? 120 ILE C CG2 1 
ATOM   4904  C  CD1 . ILE C 1 120 ? 45.709  95.200  42.487  1.00 17.41  ? 120 ILE C CD1 1 
ATOM   4905  N  N   . VAL C 1 121 ? 49.467  98.969  45.220  1.00 18.71  ? 121 VAL C N   1 
ATOM   4906  C  CA  . VAL C 1 121 ? 50.758  99.652  45.253  1.00 18.88  ? 121 VAL C CA  1 
ATOM   4907  C  C   . VAL C 1 121 ? 51.598  98.922  46.286  1.00 19.84  ? 121 VAL C C   1 
ATOM   4908  O  O   . VAL C 1 121 ? 51.073  98.205  47.140  1.00 19.71  ? 121 VAL C O   1 
ATOM   4909  C  CB  . VAL C 1 121 ? 50.608  101.154 45.625  1.00 18.88  ? 121 VAL C CB  1 
ATOM   4910  C  CG1 . VAL C 1 121 ? 50.271  101.273 47.085  1.00 17.27  ? 121 VAL C CG1 1 
ATOM   4911  C  CG2 . VAL C 1 121 ? 51.860  101.962 45.315  1.00 16.37  ? 121 VAL C CG2 1 
ATOM   4912  N  N   . ARG C 1 122 ? 52.916  99.094  46.198  1.00 20.75  ? 122 ARG C N   1 
ATOM   4913  C  CA  . ARG C 1 122 ? 53.803  98.556  47.222  1.00 20.45  ? 122 ARG C CA  1 
ATOM   4914  C  C   . ARG C 1 122 ? 53.547  99.212  48.572  1.00 19.28  ? 122 ARG C C   1 
ATOM   4915  O  O   . ARG C 1 122 ? 53.487  100.436 48.682  1.00 19.18  ? 122 ARG C O   1 
ATOM   4916  C  CB  . ARG C 1 122 ? 55.264  98.755  46.811  1.00 20.96  ? 122 ARG C CB  1 
ATOM   4917  C  CG  . ARG C 1 122 ? 55.737  97.759  45.743  1.00 22.29  ? 122 ARG C CG  1 
ATOM   4918  C  CD  . ARG C 1 122 ? 57.261  97.651  45.724  1.00 22.09  ? 122 ARG C CD  1 
ATOM   4919  N  NE  . ARG C 1 122 ? 57.722  97.027  46.954  1.00 26.00  ? 122 ARG C NE  1 
ATOM   4920  C  CZ  . ARG C 1 122 ? 58.973  96.642  47.173  1.00 27.96  ? 122 ARG C CZ  1 
ATOM   4921  N  NH1 . ARG C 1 122 ? 59.921  96.823  46.265  1.00 23.30  ? 122 ARG C NH1 1 
ATOM   4922  N  NH2 . ARG C 1 122 ? 59.279  96.066  48.331  1.00 26.97  ? 122 ARG C NH2 1 
ATOM   4923  N  N   . ARG C 1 123 ? 53.378  98.383  49.601  1.00 19.60  ? 123 ARG C N   1 
ATOM   4924  C  CA  . ARG C 1 123 ? 53.269  98.900  50.965  1.00 17.85  ? 123 ARG C CA  1 
ATOM   4925  C  C   . ARG C 1 123 ? 54.357  99.915  51.285  1.00 19.75  ? 123 ARG C C   1 
ATOM   4926  O  O   . ARG C 1 123 ? 54.089  100.945 51.919  1.00 19.95  ? 123 ARG C O   1 
ATOM   4927  C  CB  . ARG C 1 123 ? 53.338  97.755  51.978  1.00 21.28  ? 123 ARG C CB  1 
ATOM   4928  C  CG  . ARG C 1 123 ? 53.503  98.214  53.452  1.00 21.53  ? 123 ARG C CG  1 
ATOM   4929  C  CD  . ARG C 1 123 ? 53.187  97.078  54.444  1.00 22.38  ? 123 ARG C CD  1 
ATOM   4930  N  NE  . ARG C 1 123 ? 51.750  96.956  54.682  1.00 27.73  ? 123 ARG C NE  1 
ATOM   4931  C  CZ  . ARG C 1 123 ? 51.032  97.828  55.379  1.00 29.27  ? 123 ARG C CZ  1 
ATOM   4932  N  NH1 . ARG C 1 123 ? 51.586  98.897  55.934  1.00 26.13  ? 123 ARG C NH1 1 
ATOM   4933  N  NH2 . ARG C 1 123 ? 49.722  97.627  55.525  1.00 32.92  ? 123 ARG C NH2 1 
ATOM   4934  N  N   . CYS C 1 124 ? 55.602  99.647  50.880  1.00 18.87  ? 124 CYS C N   1 
ATOM   4935  C  CA  . CYS C 1 124 ? 56.637  100.575 51.317  1.00 21.64  ? 124 CYS C CA  1 
ATOM   4936  C  C   . CYS C 1 124 ? 56.535  101.916 50.598  1.00 18.33  ? 124 CYS C C   1 
ATOM   4937  O  O   . CYS C 1 124 ? 57.062  102.910 51.102  1.00 16.68  ? 124 CYS C O   1 
ATOM   4938  C  CB  . CYS C 1 124 ? 58.028  99.958  51.157  1.00 22.62  ? 124 CYS C CB  1 
ATOM   4939  S  SG  . CYS C 1 124 ? 58.483  99.645  49.485  1.00 30.04  ? 124 CYS C SG  1 
ATOM   4940  N  N   . GLU C 1 125 ? 55.825  101.976 49.468  1.00 18.68  ? 125 GLU C N   1 
ATOM   4941  C  CA  . GLU C 1 125 ? 55.564  103.264 48.835  1.00 17.85  ? 125 GLU C CA  1 
ATOM   4942  C  C   . GLU C 1 125 ? 54.453  104.004 49.569  1.00 21.11  ? 125 GLU C C   1 
ATOM   4943  O  O   . GLU C 1 125 ? 54.580  105.198 49.867  1.00 21.26  ? 125 GLU C O   1 
ATOM   4944  C  CB  . GLU C 1 125 ? 55.205  103.077 47.359  1.00 17.79  ? 125 GLU C CB  1 
ATOM   4945  C  CG  . GLU C 1 125 ? 54.990  104.383 46.571  1.00 15.44  ? 125 GLU C CG  1 
ATOM   4946  C  CD  . GLU C 1 125 ? 56.276  105.229 46.411  1.00 22.11  ? 125 GLU C CD  1 
ATOM   4947  O  OE1 . GLU C 1 125 ? 57.407  104.713 46.635  1.00 16.29  ? 125 GLU C OE1 1 
ATOM   4948  O  OE2 . GLU C 1 125 ? 56.144  106.432 46.064  1.00 22.02  ? 125 GLU C OE2 1 
ATOM   4949  N  N   . TYR C 1 126 ? 53.373  103.299 49.901  1.00 21.81  ? 126 TYR C N   1 
ATOM   4950  C  CA  . TYR C 1 126 ? 52.318  103.911 50.703  1.00 20.52  ? 126 TYR C CA  1 
ATOM   4951  C  C   . TYR C 1 126 ? 52.888  104.463 52.009  1.00 20.63  ? 126 TYR C C   1 
ATOM   4952  O  O   . TYR C 1 126 ? 52.628  105.612 52.380  1.00 23.15  ? 126 TYR C O   1 
ATOM   4953  C  CB  . TYR C 1 126 ? 51.223  102.876 50.971  1.00 22.41  ? 126 TYR C CB  1 
ATOM   4954  C  CG  . TYR C 1 126 ? 50.089  103.370 51.817  1.00 23.19  ? 126 TYR C CG  1 
ATOM   4955  C  CD1 . TYR C 1 126 ? 49.050  104.091 51.258  1.00 25.03  ? 126 TYR C CD1 1 
ATOM   4956  C  CD2 . TYR C 1 126 ? 50.062  103.126 53.184  1.00 27.49  ? 126 TYR C CD2 1 
ATOM   4957  C  CE1 . TYR C 1 126 ? 47.998  104.546 52.040  1.00 33.73  ? 126 TYR C CE1 1 
ATOM   4958  C  CE2 . TYR C 1 126 ? 49.028  103.574 53.974  1.00 27.17  ? 126 TYR C CE2 1 
ATOM   4959  C  CZ  . TYR C 1 126 ? 47.994  104.279 53.402  1.00 35.99  ? 126 TYR C CZ  1 
ATOM   4960  O  OH  . TYR C 1 126 ? 46.957  104.722 54.198  1.00 39.67  ? 126 TYR C OH  1 
ATOM   4961  N  N   . GLU C 1 127 ? 53.706  103.661 52.699  1.00 19.06  ? 127 GLU C N   1 
ATOM   4962  C  CA  . GLU C 1 127 ? 54.241  104.097 53.986  1.00 20.28  ? 127 GLU C CA  1 
ATOM   4963  C  C   . GLU C 1 127 ? 55.201  105.270 53.814  1.00 21.90  ? 127 GLU C C   1 
ATOM   4964  O  O   . GLU C 1 127 ? 55.158  106.222 54.593  1.00 20.20  ? 127 GLU C O   1 
ATOM   4965  C  CB  . GLU C 1 127 ? 54.917  102.928 54.705  1.00 19.64  ? 127 GLU C CB  1 
ATOM   4966  C  CG  . GLU C 1 127 ? 53.912  101.889 55.259  1.00 18.99  ? 127 GLU C CG  1 
ATOM   4967  C  CD  . GLU C 1 127 ? 54.600  100.654 55.851  1.00 22.99  ? 127 GLU C CD  1 
ATOM   4968  O  OE1 . GLU C 1 127 ? 55.792  100.459 55.564  1.00 19.85  ? 127 GLU C OE1 1 
ATOM   4969  O  OE2 . GLU C 1 127 ? 53.952  99.882  56.601  1.00 23.89  ? 127 GLU C OE2 1 
ATOM   4970  N  N   . TYR C 1 128 ? 56.060  105.235 52.786  1.00 23.75  ? 128 TYR C N   1 
ATOM   4971  C  CA  . TYR C 1 128 ? 56.944  106.372 52.556  1.00 19.59  ? 128 TYR C CA  1 
ATOM   4972  C  C   . TYR C 1 128 ? 56.147  107.623 52.172  1.00 25.69  ? 128 TYR C C   1 
ATOM   4973  O  O   . TYR C 1 128 ? 56.453  108.726 52.643  1.00 23.01  ? 128 TYR C O   1 
ATOM   4974  C  CB  . TYR C 1 128 ? 57.991  106.037 51.494  1.00 24.33  ? 128 TYR C CB  1 
ATOM   4975  C  CG  . TYR C 1 128 ? 59.054  107.108 51.408  1.00 23.98  ? 128 TYR C CG  1 
ATOM   4976  C  CD1 . TYR C 1 128 ? 60.100  107.137 52.322  1.00 22.97  ? 128 TYR C CD1 1 
ATOM   4977  C  CD2 . TYR C 1 128 ? 58.972  108.133 50.462  1.00 22.21  ? 128 TYR C CD2 1 
ATOM   4978  C  CE1 . TYR C 1 128 ? 61.063  108.130 52.274  1.00 19.43  ? 128 TYR C CE1 1 
ATOM   4979  C  CE2 . TYR C 1 128 ? 59.937  109.132 50.397  1.00 22.45  ? 128 TYR C CE2 1 
ATOM   4980  C  CZ  . TYR C 1 128 ? 60.977  109.118 51.316  1.00 23.44  ? 128 TYR C CZ  1 
ATOM   4981  O  OH  . TYR C 1 128 ? 61.937  110.093 51.282  1.00 23.34  ? 128 TYR C OH  1 
ATOM   4982  N  N   . ALA C 1 129 ? 55.090  107.459 51.369  1.00 23.04  ? 129 ALA C N   1 
ATOM   4983  C  CA  . ALA C 1 129 ? 54.241  108.591 51.003  1.00 20.43  ? 129 ALA C CA  1 
ATOM   4984  C  C   . ALA C 1 129 ? 53.622  109.243 52.228  1.00 25.29  ? 129 ALA C C   1 
ATOM   4985  O  O   . ALA C 1 129 ? 53.441  110.468 52.259  1.00 24.89  ? 129 ALA C O   1 
ATOM   4986  C  CB  . ALA C 1 129 ? 53.136  108.149 50.037  1.00 19.25  ? 129 ALA C CB  1 
ATOM   4987  N  N   . MET C 1 130 ? 53.269  108.440 53.240  1.00 22.47  ? 130 MET C N   1 
ATOM   4988  C  CA  . MET C 1 130 ? 52.680  108.999 54.449  1.00 22.79  ? 130 MET C CA  1 
ATOM   4989  C  C   . MET C 1 130 ? 53.696  109.666 55.369  1.00 24.41  ? 130 MET C C   1 
ATOM   4990  O  O   . MET C 1 130 ? 53.299  110.500 56.185  1.00 23.67  ? 130 MET C O   1 
ATOM   4991  C  CB  . MET C 1 130 ? 51.934  107.922 55.232  1.00 26.10  ? 130 MET C CB  1 
ATOM   4992  C  CG  . MET C 1 130 ? 50.683  107.422 54.525  1.00 27.71  ? 130 MET C CG  1 
ATOM   4993  S  SD  . MET C 1 130 ? 49.520  108.779 54.312  1.00 34.90  ? 130 MET C SD  1 
ATOM   4994  C  CE  . MET C 1 130 ? 48.176  108.151 55.305  1.00 40.99  ? 130 MET C CE  1 
ATOM   4995  N  N   . ALA C 1 131 ? 54.989  109.328 55.274  1.00 23.08  ? 131 ALA C N   1 
ATOM   4996  C  CA  . ALA C 1 131 ? 56.001  109.883 56.182  1.00 26.42  ? 131 ALA C CA  1 
ATOM   4997  C  C   . ALA C 1 131 ? 57.316  110.107 55.442  1.00 22.30  ? 131 ALA C C   1 
ATOM   4998  O  O   . ALA C 1 131 ? 58.332  109.479 55.739  1.00 23.21  ? 131 ALA C O   1 
ATOM   4999  C  CB  . ALA C 1 131 ? 56.187  108.970 57.396  1.00 22.16  ? 131 ALA C CB  1 
ATOM   5000  N  N   . PRO C 1 132 ? 57.325  111.002 54.461  1.00 24.46  ? 132 PRO C N   1 
ATOM   5001  C  CA  . PRO C 1 132 ? 58.507  111.168 53.604  1.00 25.29  ? 132 PRO C CA  1 
ATOM   5002  C  C   . PRO C 1 132 ? 59.565  112.054 54.252  1.00 26.81  ? 132 PRO C C   1 
ATOM   5003  O  O   . PRO C 1 132 ? 59.328  112.712 55.266  1.00 30.02  ? 132 PRO C O   1 
ATOM   5004  C  CB  . PRO C 1 132 ? 57.918  111.839 52.362  1.00 25.18  ? 132 PRO C CB  1 
ATOM   5005  C  CG  . PRO C 1 132 ? 56.828  112.728 52.964  1.00 23.11  ? 132 PRO C CG  1 
ATOM   5006  C  CD  . PRO C 1 132 ? 56.228  111.913 54.080  1.00 24.37  ? 132 PRO C CD  1 
ATOM   5007  N  N   . ASP C 1 133 ? 60.752  112.059 53.643  1.00 24.70  ? 133 ASP C N   1 
ATOM   5008  C  CA  . ASP C 1 133 ? 61.808  112.979 54.061  1.00 29.38  ? 133 ASP C CA  1 
ATOM   5009  C  C   . ASP C 1 133 ? 61.623  114.361 53.413  1.00 28.85  ? 133 ASP C C   1 
ATOM   5010  O  O   . ASP C 1 133 ? 60.847  114.538 52.466  1.00 27.49  ? 133 ASP C O   1 
ATOM   5011  C  CB  . ASP C 1 133 ? 63.189  112.429 53.702  1.00 23.99  ? 133 ASP C CB  1 
ATOM   5012  C  CG  . ASP C 1 133 ? 63.440  111.060 54.268  1.00 28.29  ? 133 ASP C CG  1 
ATOM   5013  O  OD1 . ASP C 1 133 ? 63.629  110.933 55.511  1.00 26.41  ? 133 ASP C OD1 1 
ATOM   5014  O  OD2 . ASP C 1 133 ? 63.480  110.107 53.451  1.00 27.60  ? 133 ASP C OD2 1 
ATOM   5015  N  N   . TRP C 1 134 ? 62.374  115.348 53.914  1.00 27.27  ? 134 TRP C N   1 
ATOM   5016  C  CA  . TRP C 1 134 ? 62.144  116.731 53.486  1.00 27.81  ? 134 TRP C CA  1 
ATOM   5017  C  C   . TRP C 1 134 ? 62.385  116.927 51.990  1.00 28.26  ? 134 TRP C C   1 
ATOM   5018  O  O   . TRP C 1 134 ? 61.688  117.726 51.362  1.00 29.38  ? 134 TRP C O   1 
ATOM   5019  C  CB  . TRP C 1 134 ? 63.011  117.707 54.311  1.00 28.58  ? 134 TRP C CB  1 
ATOM   5020  C  CG  . TRP C 1 134 ? 64.509  117.625 54.055  1.00 27.11  ? 134 TRP C CG  1 
ATOM   5021  C  CD1 . TRP C 1 134 ? 65.450  116.945 54.800  1.00 27.15  ? 134 TRP C CD1 1 
ATOM   5022  C  CD2 . TRP C 1 134 ? 65.225  118.270 53.007  1.00 28.54  ? 134 TRP C CD2 1 
ATOM   5023  N  NE1 . TRP C 1 134 ? 66.704  117.111 54.255  1.00 23.50  ? 134 TRP C NE1 1 
ATOM   5024  C  CE2 . TRP C 1 134 ? 66.593  117.924 53.154  1.00 30.70  ? 134 TRP C CE2 1 
ATOM   5025  C  CE3 . TRP C 1 134 ? 64.848  119.103 51.946  1.00 28.38  ? 134 TRP C CE3 1 
ATOM   5026  C  CZ2 . TRP C 1 134 ? 67.571  118.382 52.276  1.00 27.42  ? 134 TRP C CZ2 1 
ATOM   5027  C  CZ3 . TRP C 1 134 ? 65.820  119.547 51.076  1.00 26.13  ? 134 TRP C CZ3 1 
ATOM   5028  C  CH2 . TRP C 1 134 ? 67.165  119.191 51.249  1.00 31.57  ? 134 TRP C CH2 1 
ATOM   5029  N  N   . PHE C 1 135 ? 63.350  116.213 51.390  1.00 26.30  ? 135 PHE C N   1 
ATOM   5030  C  CA  . PHE C 1 135 ? 63.624  116.426 49.969  1.00 26.67  ? 135 PHE C CA  1 
ATOM   5031  C  C   . PHE C 1 135 ? 62.509  115.908 49.059  1.00 30.97  ? 135 PHE C C   1 
ATOM   5032  O  O   . PHE C 1 135 ? 62.404  116.357 47.915  1.00 27.09  ? 135 PHE C O   1 
ATOM   5033  C  CB  . PHE C 1 135 ? 64.954  115.779 49.553  1.00 29.10  ? 135 PHE C CB  1 
ATOM   5034  C  CG  . PHE C 1 135 ? 64.893  114.272 49.405  1.00 25.61  ? 135 PHE C CG  1 
ATOM   5035  C  CD1 . PHE C 1 135 ? 65.010  113.448 50.511  1.00 24.63  ? 135 PHE C CD1 1 
ATOM   5036  C  CD2 . PHE C 1 135 ? 64.724  113.685 48.163  1.00 28.10  ? 135 PHE C CD2 1 
ATOM   5037  C  CE1 . PHE C 1 135 ? 64.960  112.053 50.382  1.00 24.10  ? 135 PHE C CE1 1 
ATOM   5038  C  CE2 . PHE C 1 135 ? 64.674  112.292 48.023  1.00 26.82  ? 135 PHE C CE2 1 
ATOM   5039  C  CZ  . PHE C 1 135 ? 64.802  111.480 49.146  1.00 25.64  ? 135 PHE C CZ  1 
ATOM   5040  N  N   . SER C 1 136 ? 61.681  114.976 49.520  1.00 29.40  ? 136 SER C N   1 
ATOM   5041  C  CA  . SER C 1 136 ? 60.663  114.401 48.654  1.00 28.84  ? 136 SER C CA  1 
ATOM   5042  C  C   . SER C 1 136 ? 59.241  114.710 49.093  1.00 26.58  ? 136 SER C C   1 
ATOM   5043  O  O   . SER C 1 136 ? 58.304  114.336 48.382  1.00 28.19  ? 136 SER C O   1 
ATOM   5044  C  CB  . SER C 1 136 ? 60.832  112.878 48.570  1.00 28.20  ? 136 SER C CB  1 
ATOM   5045  O  OG  . SER C 1 136 ? 60.855  112.333 49.870  1.00 31.78  ? 136 SER C OG  1 
ATOM   5046  N  N   . ALA C 1 137 ? 59.047  115.377 50.233  1.00 26.47  ? 137 ALA C N   1 
ATOM   5047  C  CA  . ALA C 1 137 ? 57.696  115.568 50.752  1.00 25.05  ? 137 ALA C CA  1 
ATOM   5048  C  C   . ALA C 1 137 ? 56.805  116.332 49.776  1.00 28.29  ? 137 ALA C C   1 
ATOM   5049  O  O   . ALA C 1 137 ? 55.599  116.080 49.721  1.00 29.25  ? 137 ALA C O   1 
ATOM   5050  C  CB  . ALA C 1 137 ? 57.747  116.296 52.094  1.00 25.01  ? 137 ALA C CB  1 
ATOM   5051  N  N   . GLY C 1 138 ? 57.371  117.275 49.011  1.00 30.56  ? 138 GLY C N   1 
ATOM   5052  C  CA  . GLY C 1 138 ? 56.584  118.054 48.063  1.00 30.57  ? 138 GLY C CA  1 
ATOM   5053  C  C   . GLY C 1 138 ? 56.044  117.249 46.896  1.00 34.60  ? 138 GLY C C   1 
ATOM   5054  O  O   . GLY C 1 138 ? 55.044  117.653 46.288  1.00 33.55  ? 138 GLY C O   1 
ATOM   5055  N  N   . GLY C 1 139 ? 56.672  116.108 46.582  1.00 28.24  ? 139 GLY C N   1 
ATOM   5056  C  CA  . GLY C 1 139 ? 56.231  115.254 45.493  1.00 26.06  ? 139 GLY C CA  1 
ATOM   5057  C  C   . GLY C 1 139 ? 55.070  114.335 45.817  1.00 26.41  ? 139 GLY C C   1 
ATOM   5058  O  O   . GLY C 1 139 ? 54.577  113.640 44.923  1.00 28.48  ? 139 GLY C O   1 
ATOM   5059  N  N   . TYR C 1 140 ? 54.622  114.325 47.058  1.00 26.03  ? 140 TYR C N   1 
ATOM   5060  C  CA  . TYR C 1 140 ? 53.544  113.454 47.521  1.00 25.84  ? 140 TYR C CA  1 
ATOM   5061  C  C   . TYR C 1 140 ? 52.354  114.318 47.919  1.00 28.76  ? 140 TYR C C   1 
ATOM   5062  O  O   . TYR C 1 140 ? 52.406  114.998 48.950  1.00 28.23  ? 140 TYR C O   1 
ATOM   5063  C  CB  . TYR C 1 140 ? 54.002  112.612 48.713  1.00 23.08  ? 140 TYR C CB  1 
ATOM   5064  C  CG  . TYR C 1 140 ? 54.919  111.490 48.310  1.00 25.58  ? 140 TYR C CG  1 
ATOM   5065  C  CD1 . TYR C 1 140 ? 54.416  110.359 47.663  1.00 20.67  ? 140 TYR C CD1 1 
ATOM   5066  C  CD2 . TYR C 1 140 ? 56.299  111.569 48.554  1.00 23.31  ? 140 TYR C CD2 1 
ATOM   5067  C  CE1 . TYR C 1 140 ? 55.261  109.332 47.274  1.00 25.80  ? 140 TYR C CE1 1 
ATOM   5068  C  CE2 . TYR C 1 140 ? 57.145  110.554 48.181  1.00 20.27  ? 140 TYR C CE2 1 
ATOM   5069  C  CZ  . TYR C 1 140 ? 56.617  109.429 47.547  1.00 21.21  ? 140 TYR C CZ  1 
ATOM   5070  O  OH  . TYR C 1 140 ? 57.442  108.414 47.157  1.00 24.25  ? 140 TYR C OH  1 
ATOM   5071  N  N   . ILE C 1 141 ? 51.278  114.264 47.129  1.00 26.47  ? 141 ILE C N   1 
ATOM   5072  C  CA  . ILE C 1 141 ? 50.092  115.093 47.354  1.00 28.66  ? 141 ILE C CA  1 
ATOM   5073  C  C   . ILE C 1 141 ? 49.103  114.294 48.195  1.00 27.96  ? 141 ILE C C   1 
ATOM   5074  O  O   . ILE C 1 141 ? 48.385  113.432 47.685  1.00 28.71  ? 141 ILE C O   1 
ATOM   5075  C  CB  . ILE C 1 141 ? 49.465  115.549 46.037  1.00 31.48  ? 141 ILE C CB  1 
ATOM   5076  C  CG1 . ILE C 1 141 ? 50.531  116.159 45.137  1.00 27.78  ? 141 ILE C CG1 1 
ATOM   5077  C  CG2 . ILE C 1 141 ? 48.355  116.554 46.305  1.00 29.66  ? 141 ILE C CG2 1 
ATOM   5078  C  CD1 . ILE C 1 141 ? 51.240  117.347 45.775  1.00 28.08  ? 141 ILE C CD1 1 
ATOM   5079  N  N   . ARG C 1 142 ? 49.043  114.603 49.491  1.00 29.36  ? 142 ARG C N   1 
ATOM   5080  C  CA  . ARG C 1 142 ? 48.136  113.889 50.393  1.00 33.55  ? 142 ARG C CA  1 
ATOM   5081  C  C   . ARG C 1 142 ? 46.682  113.981 49.936  1.00 32.06  ? 142 ARG C C   1 
ATOM   5082  O  O   . ARG C 1 142 ? 45.907  113.032 50.128  1.00 30.73  ? 142 ARG C O   1 
ATOM   5083  C  CB  . ARG C 1 142 ? 48.296  114.423 51.819  1.00 41.83  ? 142 ARG C CB  1 
ATOM   5084  C  CG  . ARG C 1 142 ? 47.124  114.089 52.748  1.00 46.80  ? 142 ARG C CG  1 
ATOM   5085  C  CD  . ARG C 1 142 ? 47.459  114.222 54.225  1.00 56.48  ? 142 ARG C CD  1 
ATOM   5086  N  NE  . ARG C 1 142 ? 48.169  113.055 54.733  1.00 54.67  ? 142 ARG C NE  1 
ATOM   5087  C  CZ  . ARG C 1 142 ? 49.489  112.970 54.794  1.00 50.11  ? 142 ARG C CZ  1 
ATOM   5088  N  NH1 . ARG C 1 142 ? 50.256  113.968 54.397  1.00 47.78  ? 142 ARG C NH1 1 
ATOM   5089  N  NH2 . ARG C 1 142 ? 50.049  111.858 55.268  1.00 47.69  ? 142 ARG C NH2 1 
ATOM   5090  N  N   . ALA C 1 143 ? 46.297  115.096 49.306  1.00 29.43  ? 143 ALA C N   1 
ATOM   5091  C  CA  . ALA C 1 143 ? 44.931  115.241 48.815  1.00 32.73  ? 143 ALA C CA  1 
ATOM   5092  C  C   . ALA C 1 143 ? 44.576  114.172 47.794  1.00 31.46  ? 143 ALA C C   1 
ATOM   5093  O  O   . ALA C 1 143 ? 43.390  113.872 47.613  1.00 29.05  ? 143 ALA C O   1 
ATOM   5094  C  CB  . ALA C 1 143 ? 44.720  116.630 48.204  1.00 28.97  ? 143 ALA C CB  1 
ATOM   5095  N  N   . ASP C 1 144 ? 45.576  113.582 47.140  1.00 31.96  ? 144 ASP C N   1 
ATOM   5096  C  CA  . ASP C 1 144 ? 45.322  112.500 46.193  1.00 28.98  ? 144 ASP C CA  1 
ATOM   5097  C  C   . ASP C 1 144 ? 45.169  111.148 46.891  1.00 30.64  ? 144 ASP C C   1 
ATOM   5098  O  O   . ASP C 1 144 ? 44.126  110.494 46.774  1.00 33.71  ? 144 ASP C O   1 
ATOM   5099  C  CB  . ASP C 1 144 ? 46.445  112.445 45.151  1.00 28.72  ? 144 ASP C CB  1 
ATOM   5100  C  CG  . ASP C 1 144 ? 46.226  113.421 44.009  1.00 28.35  ? 144 ASP C CG  1 
ATOM   5101  O  OD1 . ASP C 1 144 ? 45.101  113.965 43.889  1.00 26.92  ? 144 ASP C OD1 1 
ATOM   5102  O  OD2 . ASP C 1 144 ? 47.179  113.640 43.228  1.00 29.49  ? 144 ASP C OD2 1 
ATOM   5103  N  N   . PHE C 1 145 ? 46.200  110.711 47.623  1.00 27.32  ? 145 PHE C N   1 
ATOM   5104  C  CA  . PHE C 1 145 ? 46.296  109.320 48.049  1.00 26.02  ? 145 PHE C CA  1 
ATOM   5105  C  C   . PHE C 1 145 ? 45.849  109.087 49.478  1.00 30.24  ? 145 PHE C C   1 
ATOM   5106  O  O   . PHE C 1 145 ? 45.767  107.930 49.892  1.00 34.39  ? 145 PHE C O   1 
ATOM   5107  C  CB  . PHE C 1 145 ? 47.737  108.790 47.884  1.00 25.84  ? 145 PHE C CB  1 
ATOM   5108  C  CG  . PHE C 1 145 ? 48.770  109.526 48.718  1.00 26.96  ? 145 PHE C CG  1 
ATOM   5109  C  CD1 . PHE C 1 145 ? 48.964  109.214 50.058  1.00 28.53  ? 145 PHE C CD1 1 
ATOM   5110  C  CD2 . PHE C 1 145 ? 49.536  110.531 48.160  1.00 25.81  ? 145 PHE C CD2 1 
ATOM   5111  C  CE1 . PHE C 1 145 ? 49.897  109.899 50.819  1.00 29.12  ? 145 PHE C CE1 1 
ATOM   5112  C  CE2 . PHE C 1 145 ? 50.482  111.216 48.923  1.00 25.36  ? 145 PHE C CE2 1 
ATOM   5113  C  CZ  . PHE C 1 145 ? 50.651  110.904 50.249  1.00 27.04  ? 145 PHE C CZ  1 
ATOM   5114  N  N   . ASP C 1 146 ? 45.575  110.131 50.251  1.00 33.24  ? 146 ASP C N   1 
ATOM   5115  C  CA  . ASP C 1 146 ? 45.189  109.938 51.647  1.00 35.60  ? 146 ASP C CA  1 
ATOM   5116  C  C   . ASP C 1 146 ? 43.684  110.154 51.798  1.00 37.62  ? 146 ASP C C   1 
ATOM   5117  O  O   . ASP C 1 146 ? 43.210  111.101 52.424  1.00 39.53  ? 146 ASP C O   1 
ATOM   5118  C  CB  . ASP C 1 146 ? 45.987  110.860 52.562  1.00 38.04  ? 146 ASP C CB  1 
ATOM   5119  C  CG  . ASP C 1 146 ? 45.798  110.519 54.029  1.00 41.99  ? 146 ASP C CG  1 
ATOM   5120  O  OD1 . ASP C 1 146 ? 45.302  109.415 54.310  1.00 41.06  ? 146 ASP C OD1 1 
ATOM   5121  O  OD2 . ASP C 1 146 ? 46.145  111.347 54.898  1.00 48.28  ? 146 ASP C OD2 1 
ATOM   5122  N  N   . ARG C 1 147 ? 42.939  109.220 51.211  1.00 37.24  ? 147 ARG C N   1 
ATOM   5123  C  CA  . ARG C 1 147 ? 41.485  109.200 51.255  1.00 39.16  ? 147 ARG C CA  1 
ATOM   5124  C  C   . ARG C 1 147 ? 41.046  107.945 51.993  1.00 37.19  ? 147 ARG C C   1 
ATOM   5125  O  O   . ARG C 1 147 ? 41.368  106.828 51.548  1.00 43.78  ? 147 ARG C O   1 
ATOM   5126  C  CB  . ARG C 1 147 ? 40.905  109.235 49.840  1.00 39.86  ? 147 ARG C CB  1 
ATOM   5127  C  CG  . ARG C 1 147 ? 41.307  110.473 49.056  1.00 34.08  ? 147 ARG C CG  1 
ATOM   5128  C  CD  . ARG C 1 147 ? 40.909  110.361 47.611  1.00 33.07  ? 147 ARG C CD  1 
ATOM   5129  N  NE  . ARG C 1 147 ? 41.349  111.526 46.853  1.00 36.48  ? 147 ARG C NE  1 
ATOM   5130  C  CZ  . ARG C 1 147 ? 40.603  112.177 45.973  1.00 33.89  ? 147 ARG C CZ  1 
ATOM   5131  N  NH1 . ARG C 1 147 ? 39.378  111.779 45.676  1.00 38.92  ? 147 ARG C NH1 1 
ATOM   5132  N  NH2 . ARG C 1 147 ? 41.106  113.243 45.364  1.00 33.90  ? 147 ARG C NH2 1 
ATOM   5133  N  N   . PRO C 1 148 ? 40.331  108.059 53.115  1.00 44.63  ? 148 PRO C N   1 
ATOM   5134  C  CA  . PRO C 1 148 ? 40.064  106.866 53.937  1.00 46.15  ? 148 PRO C CA  1 
ATOM   5135  C  C   . PRO C 1 148 ? 39.040  105.904 53.352  1.00 45.00  ? 148 PRO C C   1 
ATOM   5136  O  O   . PRO C 1 148 ? 38.963  104.770 53.833  1.00 47.91  ? 148 PRO C O   1 
ATOM   5137  C  CB  . PRO C 1 148 ? 39.575  107.454 55.271  1.00 46.37  ? 148 PRO C CB  1 
ATOM   5138  C  CG  . PRO C 1 148 ? 39.975  108.902 55.240  1.00 44.64  ? 148 PRO C CG  1 
ATOM   5139  C  CD  . PRO C 1 148 ? 39.930  109.299 53.798  1.00 45.70  ? 148 PRO C CD  1 
ATOM   5140  N  N   . ASP C 1 149 ? 38.265  106.290 52.340  1.00 43.46  ? 149 ASP C N   1 
ATOM   5141  C  CA  . ASP C 1 149 ? 37.351  105.342 51.707  1.00 46.98  ? 149 ASP C CA  1 
ATOM   5142  C  C   . ASP C 1 149 ? 38.003  104.556 50.565  1.00 44.87  ? 149 ASP C C   1 
ATOM   5143  O  O   . ASP C 1 149 ? 37.331  103.726 49.940  1.00 43.23  ? 149 ASP C O   1 
ATOM   5144  C  CB  . ASP C 1 149 ? 36.091  106.063 51.196  1.00 48.71  ? 149 ASP C CB  1 
ATOM   5145  C  CG  . ASP C 1 149 ? 35.234  106.637 52.332  1.00 56.64  ? 149 ASP C CG  1 
ATOM   5146  O  OD1 . ASP C 1 149 ? 35.297  106.107 53.469  1.00 52.52  ? 149 ASP C OD1 1 
ATOM   5147  O  OD2 . ASP C 1 149 ? 34.503  107.624 52.086  1.00 57.46  ? 149 ASP C OD2 1 
ATOM   5148  N  N   . VAL C 1 150 ? 39.285  104.795 50.276  1.00 39.39  ? 150 VAL C N   1 
ATOM   5149  C  CA  . VAL C 1 150 ? 39.991  104.026 49.253  1.00 34.34  ? 150 VAL C CA  1 
ATOM   5150  C  C   . VAL C 1 150 ? 40.297  102.626 49.779  1.00 33.98  ? 150 VAL C C   1 
ATOM   5151  O  O   . VAL C 1 150 ? 40.746  102.463 50.921  1.00 31.88  ? 150 VAL C O   1 
ATOM   5152  C  CB  . VAL C 1 150 ? 41.276  104.758 48.834  1.00 34.80  ? 150 VAL C CB  1 
ATOM   5153  C  CG1 . VAL C 1 150 ? 42.204  103.827 48.093  1.00 31.45  ? 150 VAL C CG1 1 
ATOM   5154  C  CG2 . VAL C 1 150 ? 40.943  105.968 47.975  1.00 33.67  ? 150 VAL C CG2 1 
ATOM   5155  N  N   . LYS C 1 151 ? 40.040  101.608 48.951  1.00 31.87  ? 151 LYS C N   1 
ATOM   5156  C  CA  . LYS C 1 151 ? 40.360  100.211 49.258  1.00 36.17  ? 151 LYS C CA  1 
ATOM   5157  C  C   . LYS C 1 151 ? 41.726  99.872  48.673  1.00 29.50  ? 151 LYS C C   1 
ATOM   5158  O  O   . LYS C 1 151 ? 41.881  99.790  47.453  1.00 28.01  ? 151 LYS C O   1 
ATOM   5159  C  CB  . LYS C 1 151 ? 39.312  99.260  48.679  1.00 36.90  ? 151 LYS C CB  1 
ATOM   5160  C  CG  . LYS C 1 151 ? 37.975  99.228  49.372  1.00 47.77  ? 151 LYS C CG  1 
ATOM   5161  C  CD  . LYS C 1 151 ? 37.399  97.806  49.304  1.00 54.57  ? 151 LYS C CD  1 
ATOM   5162  C  CE  . LYS C 1 151 ? 36.014  97.781  48.659  1.00 60.04  ? 151 LYS C CE  1 
ATOM   5163  N  NZ  . LYS C 1 151 ? 34.942  98.239  49.583  1.00 67.91  ? 151 LYS C NZ  1 
ATOM   5164  N  N   . TRP C 1 152 ? 42.696  99.622  49.535  1.00 29.00  ? 152 TRP C N   1 
ATOM   5165  C  CA  . TRP C 1 152 ? 44.056  99.334  49.104  1.00 26.75  ? 152 TRP C CA  1 
ATOM   5166  C  C   . TRP C 1 152 ? 44.381  97.845  49.165  1.00 25.62  ? 152 TRP C C   1 
ATOM   5167  O  O   . TRP C 1 152 ? 43.928  97.123  50.053  1.00 28.52  ? 152 TRP C O   1 
ATOM   5168  C  CB  . TRP C 1 152 ? 45.055  100.078 49.983  1.00 24.58  ? 152 TRP C CB  1 
ATOM   5169  C  CG  . TRP C 1 152 ? 45.015  101.566 49.856  1.00 26.87  ? 152 TRP C CG  1 
ATOM   5170  C  CD1 . TRP C 1 152 ? 44.358  102.438 50.676  1.00 24.36  ? 152 TRP C CD1 1 
ATOM   5171  C  CD2 . TRP C 1 152 ? 45.730  102.369 48.899  1.00 25.85  ? 152 TRP C CD2 1 
ATOM   5172  N  NE1 . TRP C 1 152 ? 44.595  103.737 50.268  1.00 27.50  ? 152 TRP C NE1 1 
ATOM   5173  C  CE2 . TRP C 1 152 ? 45.434  103.719 49.183  1.00 25.58  ? 152 TRP C CE2 1 
ATOM   5174  C  CE3 . TRP C 1 152 ? 46.570  102.075 47.816  1.00 22.10  ? 152 TRP C CE3 1 
ATOM   5175  C  CZ2 . TRP C 1 152 ? 45.943  104.771 48.424  1.00 26.57  ? 152 TRP C CZ2 1 
ATOM   5176  C  CZ3 . TRP C 1 152 ? 47.094  103.134 47.066  1.00 19.89  ? 152 TRP C CZ3 1 
ATOM   5177  C  CH2 . TRP C 1 152 ? 46.780  104.456 47.375  1.00 26.75  ? 152 TRP C CH2 1 
ATOM   5178  N  N   . HIS C 1 153 ? 45.211  97.402  48.226  1.00 25.99  ? 153 HIS C N   1 
ATOM   5179  C  CA  . HIS C 1 153 ? 45.966  96.165  48.375  1.00 24.33  ? 153 HIS C CA  1 
ATOM   5180  C  C   . HIS C 1 153 ? 47.435  96.561  48.378  1.00 26.04  ? 153 HIS C C   1 
ATOM   5181  O  O   . HIS C 1 153 ? 47.992  96.924  47.334  1.00 23.69  ? 153 HIS C O   1 
ATOM   5182  C  CB  . HIS C 1 153 ? 45.662  95.155  47.270  1.00 20.36  ? 153 HIS C CB  1 
ATOM   5183  C  CG  . HIS C 1 153 ? 46.440  93.884  47.394  1.00 22.06  ? 153 HIS C CG  1 
ATOM   5184  N  ND1 . HIS C 1 153 ? 46.870  93.393  48.609  1.00 23.81  ? 153 HIS C ND1 1 
ATOM   5185  C  CD2 . HIS C 1 153 ? 46.853  92.993  46.459  1.00 23.15  ? 153 HIS C CD2 1 
ATOM   5186  C  CE1 . HIS C 1 153 ? 47.522  92.258  48.417  1.00 24.05  ? 153 HIS C CE1 1 
ATOM   5187  N  NE2 . HIS C 1 153 ? 47.533  91.997  47.120  1.00 24.90  ? 153 HIS C NE2 1 
ATOM   5188  N  N   . LEU C 1 154 ? 48.051  96.490  49.549  1.00 27.27  ? 154 LEU C N   1 
ATOM   5189  C  CA  . LEU C 1 154 ? 49.426  96.929  49.748  1.00 23.10  ? 154 LEU C CA  1 
ATOM   5190  C  C   . LEU C 1 154 ? 50.325  95.721  49.594  1.00 21.81  ? 154 LEU C C   1 
ATOM   5191  O  O   . LEU C 1 154 ? 50.345  94.844  50.461  1.00 24.78  ? 154 LEU C O   1 
ATOM   5192  C  CB  . LEU C 1 154 ? 49.592  97.579  51.121  1.00 24.30  ? 154 LEU C CB  1 
ATOM   5193  C  CG  . LEU C 1 154 ? 48.745  98.846  51.327  1.00 24.83  ? 154 LEU C CG  1 
ATOM   5194  C  CD1 . LEU C 1 154 ? 49.106  99.513  52.636  1.00 25.82  ? 154 LEU C CD1 1 
ATOM   5195  C  CD2 . LEU C 1 154 ? 48.943  99.808  50.168  1.00 23.35  ? 154 LEU C CD2 1 
ATOM   5196  N  N   . LEU C 1 155 ? 51.055  95.669  48.485  1.00 23.18  ? 155 LEU C N   1 
ATOM   5197  C  CA  . LEU C 1 155 ? 51.941  94.546  48.211  1.00 21.29  ? 155 LEU C CA  1 
ATOM   5198  C  C   . LEU C 1 155 ? 53.149  94.568  49.142  1.00 25.69  ? 155 LEU C C   1 
ATOM   5199  O  O   . LEU C 1 155 ? 53.653  95.641  49.512  1.00 22.40  ? 155 LEU C O   1 
ATOM   5200  C  CB  . LEU C 1 155 ? 52.416  94.588  46.763  1.00 20.20  ? 155 LEU C CB  1 
ATOM   5201  C  CG  . LEU C 1 155 ? 51.303  94.683  45.716  1.00 21.42  ? 155 LEU C CG  1 
ATOM   5202  C  CD1 . LEU C 1 155 ? 51.936  94.722  44.332  1.00 22.00  ? 155 LEU C CD1 1 
ATOM   5203  C  CD2 . LEU C 1 155 ? 50.372  93.488  45.844  1.00 19.86  ? 155 LEU C CD2 1 
ATOM   5204  N  N   . GLU C 1 156 ? 53.619  93.361  49.496  1.00 21.02  ? 156 GLU C N   1 
ATOM   5205  C  CA  . GLU C 1 156 ? 54.771  93.153  50.366  1.00 28.10  ? 156 GLU C CA  1 
ATOM   5206  C  C   . GLU C 1 156 ? 56.026  92.875  49.531  1.00 30.73  ? 156 GLU C C   1 
ATOM   5207  O  O   . GLU C 1 156 ? 55.986  92.796  48.299  1.00 27.32  ? 156 GLU C O   1 
ATOM   5208  C  CB  . GLU C 1 156 ? 54.513  92.001  51.347  1.00 28.42  ? 156 GLU C CB  1 
ATOM   5209  C  CG  . GLU C 1 156 ? 53.314  92.182  52.280  1.00 29.46  ? 156 GLU C CG  1 
ATOM   5210  C  CD  . GLU C 1 156 ? 53.549  93.212  53.382  1.00 32.64  ? 156 GLU C CD  1 
ATOM   5211  O  OE1 . GLU C 1 156 ? 54.686  93.722  53.523  1.00 32.98  ? 156 GLU C OE1 1 
ATOM   5212  O  OE2 . GLU C 1 156 ? 52.588  93.497  54.122  1.00 30.02  ? 156 GLU C OE2 1 
ATOM   5213  N  N   . GLY C 1 157 ? 57.158  92.722  50.228  1.00 34.14  ? 157 GLY C N   1 
ATOM   5214  C  CA  . GLY C 1 157 ? 58.436  92.554  49.553  1.00 30.25  ? 157 GLY C CA  1 
ATOM   5215  C  C   . GLY C 1 157 ? 58.527  91.305  48.706  1.00 32.67  ? 157 GLY C C   1 
ATOM   5216  O  O   . GLY C 1 157 ? 59.257  91.283  47.717  1.00 41.03  ? 157 GLY C O   1 
ATOM   5217  N  N   . HIS C 1 158 ? 57.782  90.261  49.056  1.00 31.89  ? 158 HIS C N   1 
ATOM   5218  C  CA  . HIS C 1 158 ? 57.807  89.023  48.287  1.00 34.64  ? 158 HIS C CA  1 
ATOM   5219  C  C   . HIS C 1 158 ? 56.814  89.019  47.132  1.00 34.48  ? 158 HIS C C   1 
ATOM   5220  O  O   . HIS C 1 158 ? 56.765  88.043  46.373  1.00 31.36  ? 158 HIS C O   1 
ATOM   5221  C  CB  . HIS C 1 158 ? 57.523  87.821  49.182  1.00 33.28  ? 158 HIS C CB  1 
ATOM   5222  C  CG  . HIS C 1 158 ? 58.582  87.582  50.204  1.00 48.16  ? 158 HIS C CG  1 
ATOM   5223  N  ND1 . HIS C 1 158 ? 59.785  86.978  49.913  1.00 50.72  ? 158 HIS C ND1 1 
ATOM   5224  C  CD2 . HIS C 1 158 ? 58.622  87.871  51.525  1.00 51.19  ? 158 HIS C CD2 1 
ATOM   5225  C  CE1 . HIS C 1 158 ? 60.523  86.910  51.008  1.00 48.15  ? 158 HIS C CE1 1 
ATOM   5226  N  NE2 . HIS C 1 158 ? 59.840  87.444  52.001  1.00 46.46  ? 158 HIS C NE2 1 
ATOM   5227  N  N   . ASP C 1 159 ? 56.023  90.077  46.970  1.00 28.46  ? 159 ASP C N   1 
ATOM   5228  C  CA  . ASP C 1 159 ? 54.998  90.075  45.943  1.00 27.99  ? 159 ASP C CA  1 
ATOM   5229  C  C   . ASP C 1 159 ? 55.512  90.530  44.577  1.00 24.83  ? 159 ASP C C   1 
ATOM   5230  O  O   . ASP C 1 159 ? 54.693  90.828  43.704  1.00 19.92  ? 159 ASP C O   1 
ATOM   5231  C  CB  . ASP C 1 159 ? 53.828  90.947  46.380  1.00 24.90  ? 159 ASP C CB  1 
ATOM   5232  C  CG  . ASP C 1 159 ? 53.063  90.340  47.549  1.00 29.11  ? 159 ASP C CG  1 
ATOM   5233  O  OD1 . ASP C 1 159 ? 52.847  89.112  47.550  1.00 28.30  ? 159 ASP C OD1 1 
ATOM   5234  O  OD2 . ASP C 1 159 ? 52.685  91.096  48.467  1.00 30.03  ? 159 ASP C OD2 1 
ATOM   5235  N  N   . ASP C 1 160 ? 56.836  90.601  44.380  1.00 22.41  ? 160 ASP C N   1 
ATOM   5236  C  CA  . ASP C 1 160 ? 57.376  90.948  43.070  1.00 24.24  ? 160 ASP C CA  1 
ATOM   5237  C  C   . ASP C 1 160 ? 56.775  90.040  42.012  1.00 24.32  ? 160 ASP C C   1 
ATOM   5238  O  O   . ASP C 1 160 ? 56.649  88.831  42.214  1.00 25.26  ? 160 ASP C O   1 
ATOM   5239  C  CB  . ASP C 1 160 ? 58.906  90.836  43.043  1.00 24.75  ? 160 ASP C CB  1 
ATOM   5240  C  CG  . ASP C 1 160 ? 59.532  91.613  41.872  1.00 26.31  ? 160 ASP C CG  1 
ATOM   5241  O  OD1 . ASP C 1 160 ? 58.806  92.339  41.155  1.00 24.89  ? 160 ASP C OD1 1 
ATOM   5242  O  OD2 . ASP C 1 160 ? 60.751  91.498  41.659  1.00 30.73  ? 160 ASP C OD2 1 
ATOM   5243  N  N   . GLY C 1 161 ? 56.377  90.636  40.890  1.00 22.64  ? 161 GLY C N   1 
ATOM   5244  C  CA  . GLY C 1 161 ? 55.727  89.888  39.839  1.00 20.84  ? 161 GLY C CA  1 
ATOM   5245  C  C   . GLY C 1 161 ? 54.232  89.739  39.993  1.00 23.61  ? 161 GLY C C   1 
ATOM   5246  O  O   . GLY C 1 161 ? 53.611  89.044  39.174  1.00 22.62  ? 161 GLY C O   1 
ATOM   5247  N  N   . TYR C 1 162 ? 53.629  90.399  40.989  1.00 21.73  ? 162 TYR C N   1 
ATOM   5248  C  CA  . TYR C 1 162 ? 52.212  90.208  41.293  1.00 21.87  ? 162 TYR C CA  1 
ATOM   5249  C  C   . TYR C 1 162 ? 51.353  90.295  40.030  1.00 21.55  ? 162 TYR C C   1 
ATOM   5250  O  O   . TYR C 1 162 ? 51.441  91.254  39.266  1.00 24.01  ? 162 TYR C O   1 
ATOM   5251  C  CB  . TYR C 1 162 ? 51.756  91.246  42.323  1.00 19.21  ? 162 TYR C CB  1 
ATOM   5252  C  CG  . TYR C 1 162 ? 50.315  91.082  42.753  1.00 22.57  ? 162 TYR C CG  1 
ATOM   5253  C  CD1 . TYR C 1 162 ? 49.960  90.142  43.716  1.00 20.56  ? 162 TYR C CD1 1 
ATOM   5254  C  CD2 . TYR C 1 162 ? 49.300  91.838  42.173  1.00 21.42  ? 162 TYR C CD2 1 
ATOM   5255  C  CE1 . TYR C 1 162 ? 48.645  89.973  44.112  1.00 22.05  ? 162 TYR C CE1 1 
ATOM   5256  C  CE2 . TYR C 1 162 ? 47.949  91.674  42.565  1.00 20.70  ? 162 TYR C CE2 1 
ATOM   5257  C  CZ  . TYR C 1 162 ? 47.637  90.727  43.535  1.00 23.35  ? 162 TYR C CZ  1 
ATOM   5258  O  OH  . TYR C 1 162 ? 46.335  90.538  43.949  1.00 22.04  ? 162 TYR C OH  1 
ATOM   5259  N  N   . ASP C 1 163 ? 50.533  89.273  39.811  1.00 25.58  ? 163 ASP C N   1 
ATOM   5260  C  CA  . ASP C 1 163 ? 49.764  89.110  38.583  1.00 23.17  ? 163 ASP C CA  1 
ATOM   5261  C  C   . ASP C 1 163 ? 48.335  89.572  38.860  1.00 25.03  ? 163 ASP C C   1 
ATOM   5262  O  O   . ASP C 1 163 ? 47.589  88.901  39.586  1.00 20.69  ? 163 ASP C O   1 
ATOM   5263  C  CB  . ASP C 1 163 ? 49.829  87.651  38.137  1.00 22.73  ? 163 ASP C CB  1 
ATOM   5264  C  CG  . ASP C 1 163 ? 49.132  87.396  36.790  1.00 27.14  ? 163 ASP C CG  1 
ATOM   5265  O  OD1 . ASP C 1 163 ? 48.206  88.144  36.419  1.00 26.84  ? 163 ASP C OD1 1 
ATOM   5266  O  OD2 . ASP C 1 163 ? 49.522  86.434  36.102  1.00 26.96  ? 163 ASP C OD2 1 
ATOM   5267  N  N   . VAL C 1 164 ? 47.959  90.717  38.278  1.00 23.51  ? 164 VAL C N   1 
ATOM   5268  C  CA  . VAL C 1 164 ? 46.721  91.392  38.676  1.00 21.31  ? 164 VAL C CA  1 
ATOM   5269  C  C   . VAL C 1 164 ? 45.509  90.481  38.462  1.00 25.10  ? 164 VAL C C   1 
ATOM   5270  O  O   . VAL C 1 164 ? 44.698  90.272  39.375  1.00 23.79  ? 164 VAL C O   1 
ATOM   5271  C  CB  . VAL C 1 164 ? 46.564  92.732  37.930  1.00 22.54  ? 164 VAL C CB  1 
ATOM   5272  C  CG1 . VAL C 1 164 ? 45.168  93.322  38.182  1.00 22.55  ? 164 VAL C CG1 1 
ATOM   5273  C  CG2 . VAL C 1 164 ? 47.623  93.726  38.382  1.00 19.83  ? 164 VAL C CG2 1 
ATOM   5274  N  N   . PHE C 1 165 ? 45.384  89.902  37.272  1.00 23.94  ? 165 PHE C N   1 
ATOM   5275  C  CA  . PHE C 1 165 ? 44.233  89.061  36.967  1.00 27.48  ? 165 PHE C CA  1 
ATOM   5276  C  C   . PHE C 1 165 ? 44.494  87.566  37.129  1.00 30.50  ? 165 PHE C C   1 
ATOM   5277  O  O   . PHE C 1 165 ? 43.532  86.790  37.138  1.00 32.95  ? 165 PHE C O   1 
ATOM   5278  C  CB  . PHE C 1 165 ? 43.750  89.331  35.534  1.00 26.92  ? 165 PHE C CB  1 
ATOM   5279  C  CG  . PHE C 1 165 ? 43.069  90.669  35.356  1.00 27.70  ? 165 PHE C CG  1 
ATOM   5280  C  CD1 . PHE C 1 165 ? 41.789  90.882  35.837  1.00 29.14  ? 165 PHE C CD1 1 
ATOM   5281  C  CD2 . PHE C 1 165 ? 43.708  91.701  34.696  1.00 27.23  ? 165 PHE C CD2 1 
ATOM   5282  C  CE1 . PHE C 1 165 ? 41.141  92.108  35.663  1.00 29.36  ? 165 PHE C CE1 1 
ATOM   5283  C  CE2 . PHE C 1 165 ? 43.071  92.937  34.521  1.00 31.01  ? 165 PHE C CE2 1 
ATOM   5284  C  CZ  . PHE C 1 165 ? 41.787  93.136  35.012  1.00 28.35  ? 165 PHE C CZ  1 
ATOM   5285  N  N   . GLY C 1 166 ? 45.751  87.141  37.251  1.00 27.32  ? 166 GLY C N   1 
ATOM   5286  C  CA  . GLY C 1 166 ? 46.072  85.723  37.305  1.00 24.18  ? 166 GLY C CA  1 
ATOM   5287  C  C   . GLY C 1 166 ? 46.316  85.085  35.954  1.00 33.07  ? 166 GLY C C   1 
ATOM   5288  O  O   . GLY C 1 166 ? 46.287  83.856  35.847  1.00 29.56  ? 166 GLY C O   1 
ATOM   5289  N  N   . ASP C 1 167 ? 46.573  85.882  34.915  1.00 27.16  ? 167 ASP C N   1 
ATOM   5290  C  CA  . ASP C 1 167 ? 46.623  85.358  33.558  1.00 29.38  ? 167 ASP C CA  1 
ATOM   5291  C  C   . ASP C 1 167 ? 47.776  85.950  32.760  1.00 32.43  ? 167 ASP C C   1 
ATOM   5292  O  O   . ASP C 1 167 ? 47.675  86.038  31.531  1.00 32.25  ? 167 ASP C O   1 
ATOM   5293  C  CB  . ASP C 1 167 ? 45.316  85.640  32.823  1.00 26.09  ? 167 ASP C CB  1 
ATOM   5294  C  CG  . ASP C 1 167 ? 45.047  87.133  32.671  1.00 31.25  ? 167 ASP C CG  1 
ATOM   5295  O  OD1 . ASP C 1 167 ? 45.771  87.944  33.292  1.00 29.56  ? 167 ASP C OD1 1 
ATOM   5296  O  OD2 . ASP C 1 167 ? 44.097  87.504  31.941  1.00 31.29  ? 167 ASP C OD2 1 
ATOM   5297  N  N   . ASP C 1 168 ? 48.855  86.375  33.428  1.00 26.34  ? 168 ASP C N   1 
ATOM   5298  C  CA  . ASP C 1 168 ? 50.016  87.017  32.815  1.00 31.03  ? 168 ASP C CA  1 
ATOM   5299  C  C   . ASP C 1 168 ? 49.694  88.309  32.067  1.00 27.66  ? 168 ASP C C   1 
ATOM   5300  O  O   . ASP C 1 168 ? 50.576  88.845  31.392  1.00 34.97  ? 168 ASP C O   1 
ATOM   5301  C  CB  . ASP C 1 168 ? 50.764  86.064  31.871  1.00 32.59  ? 168 ASP C CB  1 
ATOM   5302  C  CG  . ASP C 1 168 ? 52.033  85.507  32.484  1.00 39.32  ? 168 ASP C CG  1 
ATOM   5303  O  OD1 . ASP C 1 168 ? 52.516  86.049  33.498  1.00 35.07  ? 168 ASP C OD1 1 
ATOM   5304  O  OD2 . ASP C 1 168 ? 52.573  84.529  31.934  1.00 57.16  ? 168 ASP C OD2 1 
ATOM   5305  N  N   . THR C 1 169 ? 48.479  88.850  32.183  1.00 24.75  ? 169 THR C N   1 
ATOM   5306  C  CA  . THR C 1 169 ? 48.143  90.061  31.426  1.00 29.09  ? 169 THR C CA  1 
ATOM   5307  C  C   . THR C 1 169 ? 48.891  91.289  31.953  1.00 29.25  ? 169 THR C C   1 
ATOM   5308  O  O   . THR C 1 169 ? 49.438  92.072  31.168  1.00 24.33  ? 169 THR C O   1 
ATOM   5309  C  CB  . THR C 1 169 ? 46.629  90.301  31.460  1.00 29.15  ? 169 THR C CB  1 
ATOM   5310  O  OG1 . THR C 1 169 ? 45.974  89.267  30.714  1.00 37.01  ? 169 THR C OG1 1 
ATOM   5311  C  CG2 . THR C 1 169 ? 46.293  91.613  30.816  1.00 33.09  ? 169 THR C CG2 1 
ATOM   5312  N  N   . ILE C 1 170 ? 48.901  91.489  33.278  1.00 26.19  ? 170 ILE C N   1 
ATOM   5313  C  CA  . ILE C 1 170 ? 49.607  92.603  33.917  1.00 25.31  ? 170 ILE C CA  1 
ATOM   5314  C  C   . ILE C 1 170 ? 50.317  92.092  35.162  1.00 23.44  ? 170 ILE C C   1 
ATOM   5315  O  O   . ILE C 1 170 ? 49.667  91.577  36.080  1.00 24.31  ? 170 ILE C O   1 
ATOM   5316  C  CB  . ILE C 1 170 ? 48.675  93.759  34.321  1.00 22.98  ? 170 ILE C CB  1 
ATOM   5317  C  CG1 . ILE C 1 170 ? 47.553  93.954  33.306  1.00 29.20  ? 170 ILE C CG1 1 
ATOM   5318  C  CG2 . ILE C 1 170 ? 49.489  95.035  34.513  1.00 21.66  ? 170 ILE C CG2 1 
ATOM   5319  C  CD1 . ILE C 1 170 ? 46.429  94.811  33.831  1.00 29.61  ? 170 ILE C CD1 1 
ATOM   5320  N  N   . ARG C 1 171 ? 51.628  92.306  35.232  1.00 22.23  ? 171 ARG C N   1 
ATOM   5321  C  CA  . ARG C 1 171 ? 52.435  91.963  36.398  1.00 22.33  ? 171 ARG C CA  1 
ATOM   5322  C  C   . ARG C 1 171 ? 53.189  93.187  36.901  1.00 21.85  ? 171 ARG C C   1 
ATOM   5323  O  O   . ARG C 1 171 ? 53.761  93.936  36.106  1.00 20.29  ? 171 ARG C O   1 
ATOM   5324  C  CB  . ARG C 1 171 ? 53.456  90.867  36.080  1.00 23.75  ? 171 ARG C CB  1 
ATOM   5325  C  CG  . ARG C 1 171 ? 52.873  89.476  35.906  1.00 25.52  ? 171 ARG C CG  1 
ATOM   5326  C  CD  . ARG C 1 171 ? 53.921  88.500  35.387  1.00 26.24  ? 171 ARG C CD  1 
ATOM   5327  N  NE  . ARG C 1 171 ? 53.420  87.129  35.379  1.00 38.41  ? 171 ARG C NE  1 
ATOM   5328  C  CZ  . ARG C 1 171 ? 53.231  86.372  36.455  1.00 38.75  ? 171 ARG C CZ  1 
ATOM   5329  N  NH1 . ARG C 1 171 ? 53.610  86.767  37.658  1.00 31.34  ? 171 ARG C NH1 1 
ATOM   5330  N  NH2 . ARG C 1 171 ? 52.658  85.176  36.316  1.00 44.34  ? 171 ARG C NH2 1 
ATOM   5331  N  N   . PHE C 1 172 ? 53.220  93.363  38.224  1.00 19.99  ? 172 PHE C N   1 
ATOM   5332  C  CA  . PHE C 1 172 ? 54.109  94.344  38.834  1.00 21.27  ? 172 PHE C CA  1 
ATOM   5333  C  C   . PHE C 1 172 ? 55.556  93.895  38.670  1.00 22.43  ? 172 PHE C C   1 
ATOM   5334  O  O   . PHE C 1 172 ? 55.879  92.730  38.888  1.00 22.56  ? 172 PHE C O   1 
ATOM   5335  C  CB  . PHE C 1 172 ? 53.809  94.496  40.319  1.00 19.65  ? 172 PHE C CB  1 
ATOM   5336  C  CG  . PHE C 1 172 ? 52.640  95.367  40.628  1.00 18.74  ? 172 PHE C CG  1 
ATOM   5337  C  CD1 . PHE C 1 172 ? 51.354  94.937  40.352  1.00 17.07  ? 172 PHE C CD1 1 
ATOM   5338  C  CD2 . PHE C 1 172 ? 52.829  96.622  41.211  1.00 17.95  ? 172 PHE C CD2 1 
ATOM   5339  C  CE1 . PHE C 1 172 ? 50.258  95.733  40.666  1.00 19.01  ? 172 PHE C CE1 1 
ATOM   5340  C  CE2 . PHE C 1 172 ? 51.741  97.434  41.522  1.00 22.24  ? 172 PHE C CE2 1 
ATOM   5341  C  CZ  . PHE C 1 172 ? 50.448  96.990  41.250  1.00 21.40  ? 172 PHE C CZ  1 
ATOM   5342  N  N   . ILE C 1 173 ? 56.434  94.799  38.277  1.00 19.93  ? 173 ILE C N   1 
ATOM   5343  C  CA  . ILE C 1 173 ? 57.854  94.499  38.258  1.00 21.72  ? 173 ILE C CA  1 
ATOM   5344  C  C   . ILE C 1 173 ? 58.522  95.522  39.171  1.00 22.53  ? 173 ILE C C   1 
ATOM   5345  O  O   . ILE C 1 173 ? 58.698  96.692  38.792  1.00 21.44  ? 173 ILE C O   1 
ATOM   5346  C  CB  . ILE C 1 173 ? 58.442  94.518  36.846  1.00 20.85  ? 173 ILE C CB  1 
ATOM   5347  C  CG1 . ILE C 1 173 ? 57.596  93.635  35.917  1.00 20.10  ? 173 ILE C CG1 1 
ATOM   5348  C  CG2 . ILE C 1 173 ? 59.892  94.073  36.877  1.00 18.96  ? 173 ILE C CG2 1 
ATOM   5349  C  CD1 . ILE C 1 173 ? 57.800  92.108  36.108  1.00 18.92  ? 173 ILE C CD1 1 
ATOM   5350  N  N   . PHE C 1 174 ? 58.894  95.077  40.378  1.00 19.52  ? 174 PHE C N   1 
ATOM   5351  C  CA  . PHE C 1 174 ? 59.463  95.962  41.394  1.00 20.50  ? 174 PHE C CA  1 
ATOM   5352  C  C   . PHE C 1 174 ? 60.753  96.608  40.892  1.00 20.09  ? 174 PHE C C   1 
ATOM   5353  O  O   . PHE C 1 174 ? 61.698  95.919  40.491  1.00 20.00  ? 174 PHE C O   1 
ATOM   5354  C  CB  . PHE C 1 174 ? 59.713  95.184  42.693  1.00 18.59  ? 174 PHE C CB  1 
ATOM   5355  C  CG  . PHE C 1 174 ? 58.441  94.816  43.435  1.00 19.26  ? 174 PHE C CG  1 
ATOM   5356  C  CD1 . PHE C 1 174 ? 57.199  95.202  42.949  1.00 19.47  ? 174 PHE C CD1 1 
ATOM   5357  C  CD2 . PHE C 1 174 ? 58.491  94.079  44.597  1.00 22.34  ? 174 PHE C CD2 1 
ATOM   5358  C  CE1 . PHE C 1 174 ? 56.029  94.860  43.616  1.00 22.57  ? 174 PHE C CE1 1 
ATOM   5359  C  CE2 . PHE C 1 174 ? 57.318  93.737  45.278  1.00 22.94  ? 174 PHE C CE2 1 
ATOM   5360  C  CZ  . PHE C 1 174 ? 56.089  94.121  44.789  1.00 19.05  ? 174 PHE C CZ  1 
ATOM   5361  N  N   . THR C 1 175 ? 60.792  97.935  40.903  1.00 17.27  ? 175 THR C N   1 
ATOM   5362  C  CA  . THR C 1 175 ? 61.954  98.675  40.410  1.00 22.81  ? 175 THR C CA  1 
ATOM   5363  C  C   . THR C 1 175 ? 62.285  99.793  41.379  1.00 23.74  ? 175 THR C C   1 
ATOM   5364  O  O   . THR C 1 175 ? 62.167  100.972 41.042  1.00 21.73  ? 175 THR C O   1 
ATOM   5365  C  CB  . THR C 1 175 ? 61.708  99.224  38.996  1.00 21.40  ? 175 THR C CB  1 
ATOM   5366  O  OG1 . THR C 1 175 ? 60.415  99.837  38.911  1.00 20.09  ? 175 THR C OG1 1 
ATOM   5367  C  CG2 . THR C 1 175 ? 61.821  98.124  37.952  1.00 20.52  ? 175 THR C CG2 1 
ATOM   5368  N  N   . PRO C 1 176 ? 62.719  99.449  42.607  1.00 24.28  ? 176 PRO C N   1 
ATOM   5369  C  CA  . PRO C 1 176 ? 63.008  100.487 43.614  1.00 21.26  ? 176 PRO C CA  1 
ATOM   5370  C  C   . PRO C 1 176 ? 64.113  101.425 43.150  1.00 24.24  ? 176 PRO C C   1 
ATOM   5371  O  O   . PRO C 1 176 ? 64.955  101.063 42.322  1.00 20.90  ? 176 PRO C O   1 
ATOM   5372  C  CB  . PRO C 1 176 ? 63.473  99.686  44.843  1.00 22.42  ? 176 PRO C CB  1 
ATOM   5373  C  CG  . PRO C 1 176 ? 63.908  98.340  44.303  1.00 21.04  ? 176 PRO C CG  1 
ATOM   5374  C  CD  . PRO C 1 176 ? 63.051  98.086  43.082  1.00 17.85  ? 176 PRO C CD  1 
ATOM   5375  N  N   . GLY C 1 177 ? 64.125  102.628 43.725  1.00 19.68  ? 177 GLY C N   1 
ATOM   5376  C  CA  . GLY C 1 177 ? 65.234  103.547 43.516  1.00 23.73  ? 177 GLY C CA  1 
ATOM   5377  C  C   . GLY C 1 177 ? 64.789  104.968 43.252  1.00 24.09  ? 177 GLY C C   1 
ATOM   5378  O  O   . GLY C 1 177 ? 65.141  105.890 43.998  1.00 26.56  ? 177 GLY C O   1 
ATOM   5379  N  N   . HIS C 1 178 ? 63.992  105.152 42.196  1.00 25.12  ? 178 HIS C N   1 
ATOM   5380  C  CA  . HIS C 1 178 ? 63.430  106.465 41.927  1.00 21.33  ? 178 HIS C CA  1 
ATOM   5381  C  C   . HIS C 1 178 ? 62.522  106.915 43.066  1.00 25.79  ? 178 HIS C C   1 
ATOM   5382  O  O   . HIS C 1 178 ? 62.501  108.097 43.426  1.00 19.61  ? 178 HIS C O   1 
ATOM   5383  C  CB  . HIS C 1 178 ? 62.648  106.457 40.621  1.00 22.92  ? 178 HIS C CB  1 
ATOM   5384  C  CG  . HIS C 1 178 ? 61.767  107.648 40.475  1.00 23.42  ? 178 HIS C CG  1 
ATOM   5385  N  ND1 . HIS C 1 178 ? 62.269  108.909 40.251  1.00 29.51  ? 178 HIS C ND1 1 
ATOM   5386  C  CD2 . HIS C 1 178 ? 60.430  107.794 40.620  1.00 27.81  ? 178 HIS C CD2 1 
ATOM   5387  C  CE1 . HIS C 1 178 ? 61.275  109.776 40.223  1.00 29.81  ? 178 HIS C CE1 1 
ATOM   5388  N  NE2 . HIS C 1 178 ? 60.148  109.126 40.434  1.00 30.80  ? 178 HIS C NE2 1 
ATOM   5389  N  N   . ALA C 1 179 ? 61.730  105.988 43.594  1.00 22.86  ? 179 ALA C N   1 
ATOM   5390  C  CA  . ALA C 1 179 ? 60.986  106.096 44.837  1.00 19.53  ? 179 ALA C CA  1 
ATOM   5391  C  C   . ALA C 1 179 ? 61.158  104.769 45.553  1.00 21.10  ? 179 ALA C C   1 
ATOM   5392  O  O   . ALA C 1 179 ? 61.540  103.770 44.934  1.00 19.50  ? 179 ALA C O   1 
ATOM   5393  C  CB  . ALA C 1 179 ? 59.499  106.392 44.608  1.00 18.02  ? 179 ALA C CB  1 
ATOM   5394  N  N   . PRO C 1 180 ? 60.950  104.736 46.866  1.00 21.47  ? 180 PRO C N   1 
ATOM   5395  C  CA  . PRO C 1 180 ? 61.278  103.494 47.581  1.00 18.32  ? 180 PRO C CA  1 
ATOM   5396  C  C   . PRO C 1 180 ? 60.415  102.314 47.141  1.00 18.32  ? 180 PRO C C   1 
ATOM   5397  O  O   . PRO C 1 180 ? 60.920  101.192 47.049  1.00 21.15  ? 180 PRO C O   1 
ATOM   5398  C  CB  . PRO C 1 180 ? 61.078  103.880 49.053  1.00 22.34  ? 180 PRO C CB  1 
ATOM   5399  C  CG  . PRO C 1 180 ? 61.305  105.402 49.066  1.00 24.27  ? 180 PRO C CG  1 
ATOM   5400  C  CD  . PRO C 1 180 ? 60.688  105.871 47.778  1.00 17.38  ? 180 PRO C CD  1 
ATOM   5401  N  N   . GLY C 1 181 ? 59.149  102.542 46.810  1.00 17.62  ? 181 GLY C N   1 
ATOM   5402  C  CA  . GLY C 1 181 ? 58.273  101.462 46.399  1.00 21.82  ? 181 GLY C CA  1 
ATOM   5403  C  C   . GLY C 1 181 ? 57.899  101.505 44.930  1.00 22.13  ? 181 GLY C C   1 
ATOM   5404  O  O   . GLY C 1 181 ? 56.839  101.004 44.530  1.00 19.50  ? 181 GLY C O   1 
ATOM   5405  N  N   . HIS C 1 182 ? 58.763  102.096 44.110  1.00 19.30  ? 182 HIS C N   1 
ATOM   5406  C  CA  . HIS C 1 182 ? 58.459  102.198 42.690  1.00 19.11  ? 182 HIS C CA  1 
ATOM   5407  C  C   . HIS C 1 182 ? 58.298  100.824 42.057  1.00 20.50  ? 182 HIS C C   1 
ATOM   5408  O  O   . HIS C 1 182 ? 59.105  99.913  42.277  1.00 21.60  ? 182 HIS C O   1 
ATOM   5409  C  CB  . HIS C 1 182 ? 59.544  102.933 41.933  1.00 19.90  ? 182 HIS C CB  1 
ATOM   5410  C  CG  . HIS C 1 182 ? 59.161  103.211 40.516  1.00 19.49  ? 182 HIS C CG  1 
ATOM   5411  N  ND1 . HIS C 1 182 ? 59.343  102.292 39.511  1.00 22.15  ? 182 HIS C ND1 1 
ATOM   5412  C  CD2 . HIS C 1 182 ? 58.555  104.280 39.947  1.00 21.23  ? 182 HIS C CD2 1 
ATOM   5413  C  CE1 . HIS C 1 182 ? 58.893  102.792 38.371  1.00 24.79  ? 182 HIS C CE1 1 
ATOM   5414  N  NE2 . HIS C 1 182 ? 58.402  103.995 38.612  1.00 24.12  ? 182 HIS C NE2 1 
ATOM   5415  N  N   . SER C 1 183 ? 57.292  100.701 41.206  1.00 22.24  ? 183 SER C N   1 
ATOM   5416  C  CA  . SER C 1 183 ? 57.141  99.498  40.403  1.00 19.92  ? 183 SER C CA  1 
ATOM   5417  C  C   . SER C 1 183 ? 56.940  99.857  38.937  1.00 21.65  ? 183 SER C C   1 
ATOM   5418  O  O   . SER C 1 183 ? 56.279  100.847 38.608  1.00 20.68  ? 183 SER C O   1 
ATOM   5419  C  CB  . SER C 1 183 ? 55.973  98.641  40.918  1.00 19.90  ? 183 SER C CB  1 
ATOM   5420  O  OG  . SER C 1 183 ? 55.953  97.387  40.266  1.00 24.48  ? 183 SER C OG  1 
ATOM   5421  N  N   . SER C 1 184 ? 57.527  99.047  38.066  1.00 21.87  ? 184 SER C N   1 
ATOM   5422  C  CA  . SER C 1 184 ? 57.214  99.054  36.652  1.00 21.79  ? 184 SER C CA  1 
ATOM   5423  C  C   . SER C 1 184 ? 56.164  97.971  36.377  1.00 22.97  ? 184 SER C C   1 
ATOM   5424  O  O   . SER C 1 184 ? 55.748  97.233  37.274  1.00 17.91  ? 184 SER C O   1 
ATOM   5425  C  CB  . SER C 1 184 ? 58.491  98.853  35.840  1.00 21.16  ? 184 SER C CB  1 
ATOM   5426  O  OG  . SER C 1 184 ? 59.422  99.891  36.134  1.00 23.21  ? 184 SER C OG  1 
ATOM   5427  N  N   . PHE C 1 185 ? 55.712  97.880  35.124  1.00 20.64  ? 185 PHE C N   1 
ATOM   5428  C  CA  . PHE C 1 185 ? 54.702  96.894  34.775  1.00 20.94  ? 185 PHE C CA  1 
ATOM   5429  C  C   . PHE C 1 185 ? 55.092  96.164  33.505  1.00 22.83  ? 185 PHE C C   1 
ATOM   5430  O  O   . PHE C 1 185 ? 55.556  96.775  32.532  1.00 24.30  ? 185 PHE C O   1 
ATOM   5431  C  CB  . PHE C 1 185 ? 53.317  97.535  34.613  1.00 20.02  ? 185 PHE C CB  1 
ATOM   5432  C  CG  . PHE C 1 185 ? 52.831  98.191  35.853  1.00 19.09  ? 185 PHE C CG  1 
ATOM   5433  C  CD1 . PHE C 1 185 ? 52.231  97.442  36.857  1.00 19.23  ? 185 PHE C CD1 1 
ATOM   5434  C  CD2 . PHE C 1 185 ? 53.048  99.554  36.059  1.00 20.36  ? 185 PHE C CD2 1 
ATOM   5435  C  CE1 . PHE C 1 185 ? 51.804  98.034  38.035  1.00 21.07  ? 185 PHE C CE1 1 
ATOM   5436  C  CE2 . PHE C 1 185 ? 52.616  100.176 37.233  1.00 22.16  ? 185 PHE C CE2 1 
ATOM   5437  C  CZ  . PHE C 1 185 ? 51.995  99.414  38.234  1.00 19.46  ? 185 PHE C CZ  1 
ATOM   5438  N  N   . LEU C 1 186 ? 54.914  94.849  33.524  1.00 20.09  ? 186 LEU C N   1 
ATOM   5439  C  CA  . LEU C 1 186 ? 55.077  94.041  32.326  1.00 22.90  ? 186 LEU C CA  1 
ATOM   5440  C  C   . LEU C 1 186 ? 53.695  93.587  31.889  1.00 25.01  ? 186 LEU C C   1 
ATOM   5441  O  O   . LEU C 1 186 ? 53.001  92.875  32.625  1.00 25.20  ? 186 LEU C O   1 
ATOM   5442  C  CB  . LEU C 1 186 ? 56.000  92.850  32.553  1.00 19.46  ? 186 LEU C CB  1 
ATOM   5443  C  CG  . LEU C 1 186 ? 56.139  91.958  31.313  1.00 28.03  ? 186 LEU C CG  1 
ATOM   5444  C  CD1 . LEU C 1 186 ? 57.010  92.633  30.239  1.00 22.93  ? 186 LEU C CD1 1 
ATOM   5445  C  CD2 . LEU C 1 186 ? 56.686  90.573  31.659  1.00 22.70  ? 186 LEU C CD2 1 
ATOM   5446  N  N   . LEU C 1 187 ? 53.300  94.014  30.702  1.00 26.05  ? 187 LEU C N   1 
ATOM   5447  C  CA  . LEU C 1 187 ? 52.024  93.638  30.116  1.00 26.77  ? 187 LEU C CA  1 
ATOM   5448  C  C   . LEU C 1 187 ? 52.251  92.575  29.047  1.00 28.08  ? 187 LEU C C   1 
ATOM   5449  O  O   . LEU C 1 187 ? 53.308  92.524  28.414  1.00 27.39  ? 187 LEU C O   1 
ATOM   5450  C  CB  . LEU C 1 187 ? 51.341  94.861  29.514  1.00 24.69  ? 187 LEU C CB  1 
ATOM   5451  C  CG  . LEU C 1 187 ? 50.521  95.771  30.446  1.00 32.97  ? 187 LEU C CG  1 
ATOM   5452  C  CD1 . LEU C 1 187 ? 51.308  96.214  31.661  1.00 23.10  ? 187 LEU C CD1 1 
ATOM   5453  C  CD2 . LEU C 1 187 ? 50.041  97.015  29.668  1.00 32.59  ? 187 LEU C CD2 1 
ATOM   5454  N  N   . ARG C 1 188 ? 51.257  91.715  28.858  1.00 27.02  ? 188 ARG C N   1 
ATOM   5455  C  CA  . ARG C 1 188 ? 51.255  90.762  27.754  1.00 27.92  ? 188 ARG C CA  1 
ATOM   5456  C  C   . ARG C 1 188 ? 49.907  90.851  27.050  1.00 31.35  ? 188 ARG C C   1 
ATOM   5457  O  O   . ARG C 1 188 ? 48.867  90.566  27.651  1.00 27.32  ? 188 ARG C O   1 
ATOM   5458  C  CB  . ARG C 1 188 ? 51.528  89.334  28.238  1.00 27.50  ? 188 ARG C CB  1 
ATOM   5459  C  CG  . ARG C 1 188 ? 53.027  89.032  28.412  1.00 31.66  ? 188 ARG C CG  1 
ATOM   5460  C  CD  . ARG C 1 188 ? 53.261  87.647  29.011  1.00 27.95  ? 188 ARG C CD  1 
ATOM   5461  N  NE  . ARG C 1 188 ? 54.669  87.399  29.285  1.00 31.08  ? 188 ARG C NE  1 
ATOM   5462  C  CZ  . ARG C 1 188 ? 55.612  87.281  28.359  1.00 37.53  ? 188 ARG C CZ  1 
ATOM   5463  N  NH1 . ARG C 1 188 ? 55.327  87.302  27.067  1.00 34.18  ? 188 ARG C NH1 1 
ATOM   5464  N  NH2 . ARG C 1 188 ? 56.872  87.106  28.735  1.00 37.56  ? 188 ARG C NH2 1 
ATOM   5465  N  N   . LEU C 1 189 ? 49.922  91.276  25.794  1.00 29.87  ? 189 LEU C N   1 
ATOM   5466  C  CA  . LEU C 1 189 ? 48.691  91.393  25.028  1.00 27.06  ? 189 LEU C CA  1 
ATOM   5467  C  C   . LEU C 1 189 ? 48.723  90.419  23.852  1.00 31.31  ? 189 LEU C C   1 
ATOM   5468  O  O   . LEU C 1 189 ? 49.803  90.120  23.320  1.00 26.28  ? 189 LEU C O   1 
ATOM   5469  C  CB  . LEU C 1 189 ? 48.506  92.827  24.527  1.00 26.81  ? 189 LEU C CB  1 
ATOM   5470  C  CG  . LEU C 1 189 ? 48.615  93.877  25.639  1.00 28.42  ? 189 LEU C CG  1 
ATOM   5471  C  CD1 . LEU C 1 189 ? 49.069  95.209  25.060  1.00 26.46  ? 189 LEU C CD1 1 
ATOM   5472  C  CD2 . LEU C 1 189 ? 47.289  94.029  26.420  1.00 26.43  ? 189 LEU C CD2 1 
ATOM   5473  N  N   . PRO C 1 190 ? 47.555  89.901  23.430  1.00 30.59  ? 190 PRO C N   1 
ATOM   5474  C  CA  . PRO C 1 190 ? 47.545  88.783  22.456  1.00 33.68  ? 190 PRO C CA  1 
ATOM   5475  C  C   . PRO C 1 190 ? 48.233  89.093  21.137  1.00 34.06  ? 190 PRO C C   1 
ATOM   5476  O  O   . PRO C 1 190 ? 48.996  88.261  20.637  1.00 34.80  ? 190 PRO C O   1 
ATOM   5477  C  CB  . PRO C 1 190 ? 46.048  88.512  22.253  1.00 32.57  ? 190 PRO C CB  1 
ATOM   5478  C  CG  . PRO C 1 190 ? 45.384  89.076  23.495  1.00 38.09  ? 190 PRO C CG  1 
ATOM   5479  C  CD  . PRO C 1 190 ? 46.196  90.299  23.830  1.00 32.33  ? 190 PRO C CD  1 
ATOM   5480  N  N   . GLU C 1 191 ? 48.002  90.268  20.558  1.00 32.08  ? 191 GLU C N   1 
ATOM   5481  C  CA  . GLU C 1 191 ? 48.601  90.582  19.265  1.00 31.74  ? 191 GLU C CA  1 
ATOM   5482  C  C   . GLU C 1 191 ? 49.970  91.250  19.403  1.00 35.19  ? 191 GLU C C   1 
ATOM   5483  O  O   . GLU C 1 191 ? 50.920  90.890  18.697  1.00 32.21  ? 191 GLU C O   1 
ATOM   5484  C  CB  . GLU C 1 191 ? 47.654  91.482  18.447  1.00 31.84  ? 191 GLU C CB  1 
ATOM   5485  C  CG  . GLU C 1 191 ? 46.193  90.962  18.279  1.00 37.20  ? 191 GLU C CG  1 
ATOM   5486  C  CD  . GLU C 1 191 ? 46.087  89.446  18.070  1.00 39.07  ? 191 GLU C CD  1 
ATOM   5487  O  OE1 . GLU C 1 191 ? 46.761  88.936  17.166  1.00 36.44  ? 191 GLU C OE1 1 
ATOM   5488  O  OE2 . GLU C 1 191 ? 45.316  88.770  18.807  1.00 33.26  ? 191 GLU C OE2 1 
ATOM   5489  N  N   . THR C 1 192 ? 50.085  92.256  20.275  1.00 31.56  ? 192 THR C N   1 
ATOM   5490  C  CA  . THR C 1 192 ? 51.371  92.923  20.429  1.00 33.29  ? 192 THR C CA  1 
ATOM   5491  C  C   . THR C 1 192 ? 52.394  92.039  21.136  1.00 35.19  ? 192 THR C C   1 
ATOM   5492  O  O   . THR C 1 192 ? 53.586  92.100  20.818  1.00 33.40  ? 192 THR C O   1 
ATOM   5493  C  CB  . THR C 1 192 ? 51.197  94.231  21.196  1.00 34.56  ? 192 THR C CB  1 
ATOM   5494  O  OG1 . THR C 1 192 ? 50.215  95.040  20.540  1.00 31.45  ? 192 THR C OG1 1 
ATOM   5495  C  CG2 . THR C 1 192 ? 52.540  95.001  21.284  1.00 29.64  ? 192 THR C CG2 1 
ATOM   5496  N  N   . GLY C 1 193 ? 51.967  91.211  22.088  1.00 29.19  ? 193 GLY C N   1 
ATOM   5497  C  CA  . GLY C 1 193 ? 52.914  90.493  22.910  1.00 28.54  ? 193 GLY C CA  1 
ATOM   5498  C  C   . GLY C 1 193 ? 53.363  91.348  24.085  1.00 28.32  ? 193 GLY C C   1 
ATOM   5499  O  O   . GLY C 1 193 ? 52.642  92.239  24.545  1.00 28.41  ? 193 GLY C O   1 
ATOM   5500  N  N   . PRO C 1 194 ? 54.578  91.111  24.575  1.00 27.66  ? 194 PRO C N   1 
ATOM   5501  C  CA  . PRO C 1 194 ? 55.017  91.777  25.811  1.00 27.07  ? 194 PRO C CA  1 
ATOM   5502  C  C   . PRO C 1 194 ? 55.288  93.265  25.634  1.00 27.61  ? 194 PRO C C   1 
ATOM   5503  O  O   . PRO C 1 194 ? 55.936  93.696  24.674  1.00 29.32  ? 194 PRO C O   1 
ATOM   5504  C  CB  . PRO C 1 194 ? 56.300  91.019  26.179  1.00 29.09  ? 194 PRO C CB  1 
ATOM   5505  C  CG  . PRO C 1 194 ? 56.796  90.465  24.868  1.00 31.59  ? 194 PRO C CG  1 
ATOM   5506  C  CD  . PRO C 1 194 ? 55.559  90.121  24.091  1.00 24.07  ? 194 PRO C CD  1 
ATOM   5507  N  N   . VAL C 1 195 ? 54.808  94.049  26.599  1.00 24.24  ? 195 VAL C N   1 
ATOM   5508  C  CA  . VAL C 1 195 ? 55.043  95.488  26.665  1.00 23.70  ? 195 VAL C CA  1 
ATOM   5509  C  C   . VAL C 1 195 ? 55.521  95.825  28.074  1.00 26.84  ? 195 VAL C C   1 
ATOM   5510  O  O   . VAL C 1 195 ? 54.832  95.523  29.055  1.00 24.32  ? 195 VAL C O   1 
ATOM   5511  C  CB  . VAL C 1 195 ? 53.781  96.320  26.329  1.00 23.23  ? 195 VAL C CB  1 
ATOM   5512  C  CG1 . VAL C 1 195 ? 54.076  97.818  26.488  1.00 23.62  ? 195 VAL C CG1 1 
ATOM   5513  C  CG2 . VAL C 1 195 ? 53.272  96.036  24.918  1.00 22.25  ? 195 VAL C CG2 1 
ATOM   5514  N  N   . LEU C 1 196 ? 56.678  96.478  28.171  1.00 26.03  ? 196 LEU C N   1 
ATOM   5515  C  CA  . LEU C 1 196 ? 57.292  96.807  29.454  1.00 22.43  ? 196 LEU C CA  1 
ATOM   5516  C  C   . LEU C 1 196 ? 57.100  98.296  29.727  1.00 27.10  ? 196 LEU C C   1 
ATOM   5517  O  O   . LEU C 1 196 ? 57.749  99.151  29.104  1.00 27.98  ? 196 LEU C O   1 
ATOM   5518  C  CB  . LEU C 1 196 ? 58.769  96.422  29.458  1.00 25.39  ? 196 LEU C CB  1 
ATOM   5519  C  CG  . LEU C 1 196 ? 59.548  96.886  30.695  1.00 27.32  ? 196 LEU C CG  1 
ATOM   5520  C  CD1 . LEU C 1 196 ? 58.828  96.441  31.969  1.00 26.61  ? 196 LEU C CD1 1 
ATOM   5521  C  CD2 . LEU C 1 196 ? 60.990  96.349  30.644  1.00 26.61  ? 196 LEU C CD2 1 
ATOM   5522  N  N   . LEU C 1 197 ? 56.199  98.605  30.657  1.00 22.94  ? 197 LEU C N   1 
ATOM   5523  C  CA  . LEU C 1 197 ? 55.981  99.983  31.094  1.00 24.90  ? 197 LEU C CA  1 
ATOM   5524  C  C   . LEU C 1 197 ? 57.017  100.302 32.170  1.00 25.35  ? 197 LEU C C   1 
ATOM   5525  O  O   . LEU C 1 197 ? 56.857  99.921  33.330  1.00 25.51  ? 197 LEU C O   1 
ATOM   5526  C  CB  . LEU C 1 197 ? 54.556  100.160 31.612  1.00 19.84  ? 197 LEU C CB  1 
ATOM   5527  C  CG  . LEU C 1 197 ? 53.430  99.897  30.596  1.00 23.06  ? 197 LEU C CG  1 
ATOM   5528  C  CD1 . LEU C 1 197 ? 52.067  100.191 31.169  1.00 18.55  ? 197 LEU C CD1 1 
ATOM   5529  C  CD2 . LEU C 1 197 ? 53.618  100.706 29.317  1.00 24.38  ? 197 LEU C CD2 1 
ATOM   5530  N  N   . ALA C 1 198 ? 58.096  100.996 31.787  1.00 23.82  ? 198 ALA C N   1 
ATOM   5531  C  CA  . ALA C 1 198 ? 59.161  101.295 32.743  1.00 26.21  ? 198 ALA C CA  1 
ATOM   5532  C  C   . ALA C 1 198 ? 58.711  102.303 33.795  1.00 25.08  ? 198 ALA C C   1 
ATOM   5533  O  O   . ALA C 1 198 ? 59.172  102.257 34.944  1.00 27.87  ? 198 ALA C O   1 
ATOM   5534  C  CB  . ALA C 1 198 ? 60.407  101.820 32.013  1.00 22.36  ? 198 ALA C CB  1 
ATOM   5535  N  N   . VAL C 1 199 ? 57.787  103.180 33.432  1.00 21.38  ? 199 VAL C N   1 
ATOM   5536  C  CA  . VAL C 1 199 ? 57.435  104.350 34.227  1.00 25.50  ? 199 VAL C CA  1 
ATOM   5537  C  C   . VAL C 1 199 ? 58.722  105.080 34.611  1.00 26.99  ? 199 VAL C C   1 
ATOM   5538  O  O   . VAL C 1 199 ? 59.593  105.305 33.757  1.00 26.60  ? 199 VAL C O   1 
ATOM   5539  C  CB  . VAL C 1 199 ? 56.560  103.963 35.435  1.00 23.99  ? 199 VAL C CB  1 
ATOM   5540  C  CG1 . VAL C 1 199 ? 55.732  105.163 35.902  1.00 18.57  ? 199 VAL C CG1 1 
ATOM   5541  C  CG2 . VAL C 1 199 ? 55.630  102.784 35.049  1.00 20.55  ? 199 VAL C CG2 1 
ATOM   5542  N  N   . ASP C 1 200 ? 58.867  105.452 35.880  1.00 24.41  ? 200 ASP C N   1 
ATOM   5543  C  CA  . ASP C 1 200 ? 59.969  106.313 36.286  1.00 28.41  ? 200 ASP C CA  1 
ATOM   5544  C  C   . ASP C 1 200 ? 61.244  105.546 36.662  1.00 28.34  ? 200 ASP C C   1 
ATOM   5545  O  O   . ASP C 1 200 ? 62.207  106.166 37.130  1.00 28.31  ? 200 ASP C O   1 
ATOM   5546  C  CB  . ASP C 1 200 ? 59.517  107.220 37.429  1.00 25.30  ? 200 ASP C CB  1 
ATOM   5547  C  CG  . ASP C 1 200 ? 58.512  108.273 36.965  1.00 29.15  ? 200 ASP C CG  1 
ATOM   5548  O  OD1 . ASP C 1 200 ? 58.074  108.206 35.796  1.00 30.07  ? 200 ASP C OD1 1 
ATOM   5549  O  OD2 . ASP C 1 200 ? 58.171  109.164 37.755  1.00 25.77  ? 200 ASP C OD2 1 
ATOM   5550  N  N   . ALA C 1 201 ? 61.280  104.227 36.450  1.00 26.07  ? 201 ALA C N   1 
ATOM   5551  C  CA  . ALA C 1 201 ? 62.539  103.496 36.565  1.00 24.36  ? 201 ALA C CA  1 
ATOM   5552  C  C   . ALA C 1 201 ? 63.532  103.930 35.491  1.00 29.06  ? 201 ALA C C   1 
ATOM   5553  O  O   . ALA C 1 201 ? 64.748  103.817 35.682  1.00 28.67  ? 201 ALA C O   1 
ATOM   5554  C  CB  . ALA C 1 201 ? 62.290  101.990 36.462  1.00 18.39  ? 201 ALA C CB  1 
ATOM   5555  N  N   . ALA C 1 202 ? 63.031  104.402 34.351  1.00 27.86  ? 202 ALA C N   1 
ATOM   5556  C  CA  . ALA C 1 202 ? 63.881  104.915 33.279  1.00 29.77  ? 202 ALA C CA  1 
ATOM   5557  C  C   . ALA C 1 202 ? 63.071  105.999 32.576  1.00 32.93  ? 202 ALA C C   1 
ATOM   5558  O  O   . ALA C 1 202 ? 62.152  105.691 31.803  1.00 28.39  ? 202 ALA C O   1 
ATOM   5559  C  CB  . ALA C 1 202 ? 64.307  103.810 32.318  1.00 27.41  ? 202 ALA C CB  1 
ATOM   5560  N  N   . TYR C 1 203 ? 63.388  107.259 32.887  1.00 33.04  ? 203 TYR C N   1 
ATOM   5561  C  CA  . TYR C 1 203 ? 62.688  108.382 32.270  1.00 31.20  ? 203 TYR C CA  1 
ATOM   5562  C  C   . TYR C 1 203 ? 62.850  108.368 30.755  1.00 34.89  ? 203 TYR C C   1 
ATOM   5563  O  O   . TYR C 1 203 ? 61.888  108.613 30.016  1.00 32.45  ? 203 TYR C O   1 
ATOM   5564  C  CB  . TYR C 1 203 ? 63.237  109.697 32.806  1.00 34.08  ? 203 TYR C CB  1 
ATOM   5565  C  CG  . TYR C 1 203 ? 62.969  110.097 34.246  1.00 38.66  ? 203 TYR C CG  1 
ATOM   5566  C  CD1 . TYR C 1 203 ? 61.713  109.966 34.839  1.00 37.98  ? 203 TYR C CD1 1 
ATOM   5567  C  CD2 . TYR C 1 203 ? 63.983  110.685 34.993  1.00 39.68  ? 203 TYR C CD2 1 
ATOM   5568  C  CE1 . TYR C 1 203 ? 61.494  110.398 36.167  1.00 35.13  ? 203 TYR C CE1 1 
ATOM   5569  C  CE2 . TYR C 1 203 ? 63.782  111.117 36.284  1.00 41.07  ? 203 TYR C CE2 1 
ATOM   5570  C  CZ  . TYR C 1 203 ? 62.545  110.977 36.872  1.00 43.35  ? 203 TYR C CZ  1 
ATOM   5571  O  OH  . TYR C 1 203 ? 62.407  111.416 38.170  1.00 42.17  ? 203 TYR C OH  1 
ATOM   5572  N  N   . THR C 1 204 ? 64.072  108.116 30.274  1.00 32.61  ? 204 THR C N   1 
ATOM   5573  C  CA  . THR C 1 204 ? 64.424  108.315 28.873  1.00 36.95  ? 204 THR C CA  1 
ATOM   5574  C  C   . THR C 1 204 ? 65.356  107.209 28.399  1.00 32.25  ? 204 THR C C   1 
ATOM   5575  O  O   . THR C 1 204 ? 65.905  106.440 29.193  1.00 32.45  ? 204 THR C O   1 
ATOM   5576  C  CB  . THR C 1 204 ? 65.120  109.668 28.640  1.00 39.63  ? 204 THR C CB  1 
ATOM   5577  O  OG1 . THR C 1 204 ? 66.488  109.579 29.078  1.00 37.68  ? 204 THR C OG1 1 
ATOM   5578  C  CG2 . THR C 1 204 ? 64.412  110.801 29.392  1.00 33.34  ? 204 THR C CG2 1 
ATOM   5579  N  N   . THR C 1 205 ? 65.569  107.176 27.081  1.00 33.67  ? 205 THR C N   1 
ATOM   5580  C  CA  . THR C 1 205 ? 66.572  106.283 26.496  1.00 36.31  ? 205 THR C CA  1 
ATOM   5581  C  C   . THR C 1 205 ? 67.956  106.508 27.110  1.00 32.42  ? 205 THR C C   1 
ATOM   5582  O  O   . THR C 1 205 ? 68.722  105.557 27.292  1.00 31.29  ? 205 THR C O   1 
ATOM   5583  C  CB  . THR C 1 205 ? 66.641  106.476 24.967  1.00 33.73  ? 205 THR C CB  1 
ATOM   5584  O  OG1 . THR C 1 205 ? 66.790  107.869 24.652  1.00 41.09  ? 205 THR C OG1 1 
ATOM   5585  C  CG2 . THR C 1 205 ? 65.388  105.955 24.289  1.00 31.00  ? 205 THR C CG2 1 
ATOM   5586  N  N   . ASP C 1 206 ? 68.297  107.765 27.417  1.00 30.79  ? 206 ASP C N   1 
ATOM   5587  C  CA  . ASP C 1 206 ? 69.568  108.062 28.078  1.00 36.61  ? 206 ASP C CA  1 
ATOM   5588  C  C   . ASP C 1 206 ? 69.698  107.293 29.395  1.00 35.84  ? 206 ASP C C   1 
ATOM   5589  O  O   . ASP C 1 206 ? 70.720  106.643 29.654  1.00 33.29  ? 206 ASP C O   1 
ATOM   5590  C  CB  . ASP C 1 206 ? 69.695  109.574 28.323  1.00 35.57  ? 206 ASP C CB  1 
ATOM   5591  C  CG  . ASP C 1 206 ? 70.289  110.319 27.130  1.00 43.80  ? 206 ASP C CG  1 
ATOM   5592  O  OD1 . ASP C 1 206 ? 70.589  109.665 26.101  1.00 44.88  ? 206 ASP C OD1 1 
ATOM   5593  O  OD2 . ASP C 1 206 ? 70.461  111.554 27.225  1.00 44.36  ? 206 ASP C OD2 1 
ATOM   5594  N  N   . HIS C 1 207 ? 68.674  107.372 30.251  1.00 33.82  ? 207 HIS C N   1 
ATOM   5595  C  CA  . HIS C 1 207 ? 68.673  106.564 31.466  1.00 33.29  ? 207 HIS C CA  1 
ATOM   5596  C  C   . HIS C 1 207 ? 68.792  105.083 31.134  1.00 31.93  ? 207 HIS C C   1 
ATOM   5597  O  O   . HIS C 1 207 ? 69.622  104.367 31.707  1.00 32.20  ? 207 HIS C O   1 
ATOM   5598  C  CB  . HIS C 1 207 ? 67.406  106.837 32.276  1.00 34.22  ? 207 HIS C CB  1 
ATOM   5599  C  CG  . HIS C 1 207 ? 67.336  108.227 32.819  1.00 36.90  ? 207 HIS C CG  1 
ATOM   5600  N  ND1 . HIS C 1 207 ? 66.680  109.247 32.162  1.00 40.16  ? 207 HIS C ND1 1 
ATOM   5601  C  CD2 . HIS C 1 207 ? 67.855  108.773 33.945  1.00 37.21  ? 207 HIS C CD2 1 
ATOM   5602  C  CE1 . HIS C 1 207 ? 66.785  110.360 32.867  1.00 41.76  ? 207 HIS C CE1 1 
ATOM   5603  N  NE2 . HIS C 1 207 ? 67.495  110.100 33.952  1.00 43.42  ? 207 HIS C NE2 1 
ATOM   5604  N  N   . TRP C 1 208 ? 67.973  104.607 30.195  1.00 30.76  ? 208 TRP C N   1 
ATOM   5605  C  CA  . TRP C 1 208 ? 68.017  103.197 29.824  1.00 31.21  ? 208 TRP C CA  1 
ATOM   5606  C  C   . TRP C 1 208 ? 69.400  102.782 29.348  1.00 31.10  ? 208 TRP C C   1 
ATOM   5607  O  O   . TRP C 1 208 ? 69.840  101.659 29.613  1.00 34.23  ? 208 TRP C O   1 
ATOM   5608  C  CB  . TRP C 1 208 ? 66.989  102.911 28.737  1.00 32.64  ? 208 TRP C CB  1 
ATOM   5609  C  CG  . TRP C 1 208 ? 66.896  101.466 28.367  1.00 31.15  ? 208 TRP C CG  1 
ATOM   5610  C  CD1 . TRP C 1 208 ? 67.624  100.816 27.414  1.00 33.57  ? 208 TRP C CD1 1 
ATOM   5611  C  CD2 . TRP C 1 208 ? 66.001  100.496 28.918  1.00 29.44  ? 208 TRP C CD2 1 
ATOM   5612  N  NE1 . TRP C 1 208 ? 67.249  99.492  27.348  1.00 35.04  ? 208 TRP C NE1 1 
ATOM   5613  C  CE2 . TRP C 1 208 ? 66.249  99.271  28.256  1.00 29.35  ? 208 TRP C CE2 1 
ATOM   5614  C  CE3 . TRP C 1 208 ? 65.024  100.537 29.913  1.00 29.79  ? 208 TRP C CE3 1 
ATOM   5615  C  CZ2 . TRP C 1 208 ? 65.557  98.100  28.562  1.00 28.85  ? 208 TRP C CZ2 1 
ATOM   5616  C  CZ3 . TRP C 1 208 ? 64.328  99.377  30.206  1.00 26.80  ? 208 TRP C CZ3 1 
ATOM   5617  C  CH2 . TRP C 1 208 ? 64.597  98.175  29.535  1.00 28.55  ? 208 TRP C CH2 1 
ATOM   5618  N  N   . ASP C 1 209 ? 70.092  103.663 28.631  1.00 34.43  ? 209 ASP C N   1 
ATOM   5619  C  CA  . ASP C 1 209 ? 71.409  103.350 28.090  1.00 37.95  ? 209 ASP C CA  1 
ATOM   5620  C  C   . ASP C 1 209 ? 72.532  103.682 29.067  1.00 34.97  ? 209 ASP C C   1 
ATOM   5621  O  O   . ASP C 1 209 ? 73.706  103.500 28.728  1.00 39.34  ? 209 ASP C O   1 
ATOM   5622  C  CB  . ASP C 1 209 ? 71.627  104.102 26.761  1.00 40.68  ? 209 ASP C CB  1 
ATOM   5623  C  CG  . ASP C 1 209 ? 70.718  103.600 25.629  1.00 37.74  ? 209 ASP C CG  1 
ATOM   5624  O  OD1 . ASP C 1 209 ? 70.279  102.427 25.667  1.00 41.03  ? 209 ASP C OD1 1 
ATOM   5625  O  OD2 . ASP C 1 209 ? 70.440  104.390 24.704  1.00 38.06  ? 209 ASP C OD2 1 
ATOM   5626  N  N   . GLU C 1 210 ? 72.190  104.163 30.263  1.00 33.92  ? 210 GLU C N   1 
ATOM   5627  C  CA  . GLU C 1 210 ? 73.158  104.473 31.319  1.00 35.46  ? 210 GLU C CA  1 
ATOM   5628  C  C   . GLU C 1 210 ? 74.028  105.681 30.947  1.00 37.63  ? 210 GLU C C   1 
ATOM   5629  O  O   . GLU C 1 210 ? 75.209  105.743 31.282  1.00 36.88  ? 210 GLU C O   1 
ATOM   5630  C  CB  . GLU C 1 210 ? 74.005  103.246 31.659  1.00 32.00  ? 210 GLU C CB  1 
ATOM   5631  C  CG  . GLU C 1 210 ? 73.131  102.048 32.042  1.00 31.04  ? 210 GLU C CG  1 
ATOM   5632  C  CD  . GLU C 1 210 ? 73.918  100.820 32.471  1.00 31.45  ? 210 GLU C CD  1 
ATOM   5633  O  OE1 . GLU C 1 210 ? 75.118  100.713 32.160  1.00 36.22  ? 210 GLU C OE1 1 
ATOM   5634  O  OE2 . GLU C 1 210 ? 73.328  99.939  33.116  1.00 29.92  ? 210 GLU C OE2 1 
ATOM   5635  N  N   . LYS C 1 211 ? 73.431  106.650 30.248  1.00 38.04  ? 211 LYS C N   1 
ATOM   5636  C  CA  . LYS C 1 211 ? 74.056  107.937 29.962  1.00 44.17  ? 211 LYS C CA  1 
ATOM   5637  C  C   . LYS C 1 211 ? 73.480  109.042 30.831  1.00 43.14  ? 211 LYS C C   1 
ATOM   5638  O  O   . LYS C 1 211 ? 73.731  110.221 30.571  1.00 49.34  ? 211 LYS C O   1 
ATOM   5639  C  CB  . LYS C 1 211 ? 73.890  108.331 28.490  1.00 44.39  ? 211 LYS C CB  1 
ATOM   5640  C  CG  . LYS C 1 211 ? 73.755  107.189 27.509  1.00 47.57  ? 211 LYS C CG  1 
ATOM   5641  C  CD  . LYS C 1 211 ? 75.098  106.660 27.061  1.00 54.57  ? 211 LYS C CD  1 
ATOM   5642  C  CE  . LYS C 1 211 ? 75.197  106.668 25.540  1.00 65.99  ? 211 LYS C CE  1 
ATOM   5643  N  NZ  . LYS C 1 211 ? 76.482  106.090 25.037  1.00 70.15  ? 211 LYS C NZ  1 
ATOM   5644  N  N   . ALA C 1 212 ? 72.691  108.690 31.839  1.00 41.40  ? 212 ALA C N   1 
ATOM   5645  C  CA  . ALA C 1 212 ? 72.060  109.664 32.710  1.00 39.88  ? 212 ALA C CA  1 
ATOM   5646  C  C   . ALA C 1 212 ? 71.574  108.950 33.962  1.00 40.97  ? 212 ALA C C   1 
ATOM   5647  O  O   . ALA C 1 212 ? 71.285  107.746 33.939  1.00 38.70  ? 212 ALA C O   1 
ATOM   5648  C  CB  . ALA C 1 212 ? 70.892  110.369 32.010  1.00 40.45  ? 212 ALA C CB  1 
ATOM   5649  N  N   . LEU C 1 213 ? 71.499  109.701 35.046  1.00 41.60  ? 213 LEU C N   1 
ATOM   5650  C  CA  . LEU C 1 213 ? 70.865  109.288 36.284  1.00 39.89  ? 213 LEU C CA  1 
ATOM   5651  C  C   . LEU C 1 213 ? 69.588  110.100 36.483  1.00 40.38  ? 213 LEU C C   1 
ATOM   5652  O  O   . LEU C 1 213 ? 69.507  111.245 36.026  1.00 41.02  ? 213 LEU C O   1 
ATOM   5653  C  CB  . LEU C 1 213 ? 71.805  109.496 37.482  1.00 37.88  ? 213 LEU C CB  1 
ATOM   5654  C  CG  . LEU C 1 213 ? 73.036  108.591 37.510  1.00 38.39  ? 213 LEU C CG  1 
ATOM   5655  C  CD1 . LEU C 1 213 ? 74.011  109.035 38.609  1.00 33.80  ? 213 LEU C CD1 1 
ATOM   5656  C  CD2 . LEU C 1 213 ? 72.601  107.131 37.714  1.00 32.99  ? 213 LEU C CD2 1 
ATOM   5657  N  N   . PRO C 1 214 ? 68.565  109.547 37.137  1.00 37.25  ? 214 PRO C N   1 
ATOM   5658  C  CA  . PRO C 1 214 ? 67.356  110.343 37.385  1.00 39.50  ? 214 PRO C CA  1 
ATOM   5659  C  C   . PRO C 1 214 ? 67.709  111.593 38.181  1.00 43.81  ? 214 PRO C C   1 
ATOM   5660  O  O   . PRO C 1 214 ? 68.590  111.571 39.048  1.00 40.82  ? 214 PRO C O   1 
ATOM   5661  C  CB  . PRO C 1 214 ? 66.444  109.399 38.185  1.00 41.65  ? 214 PRO C CB  1 
ATOM   5662  C  CG  . PRO C 1 214 ? 67.076  108.029 38.127  1.00 40.35  ? 214 PRO C CG  1 
ATOM   5663  C  CD  . PRO C 1 214 ? 68.523  108.213 37.769  1.00 38.78  ? 214 PRO C CD  1 
ATOM   5664  N  N   . GLY C 1 215 ? 67.039  112.702 37.846  1.00 45.35  ? 215 GLY C N   1 
ATOM   5665  C  CA  . GLY C 1 215 ? 67.238  113.969 38.539  1.00 42.55  ? 215 GLY C CA  1 
ATOM   5666  C  C   . GLY C 1 215 ? 66.533  114.082 39.872  1.00 40.15  ? 215 GLY C C   1 
ATOM   5667  O  O   . GLY C 1 215 ? 66.752  115.050 40.605  1.00 42.24  ? 215 GLY C O   1 
ATOM   5668  N  N   . PHE C 1 216 ? 65.680  113.116 40.189  1.00 36.46  ? 216 PHE C N   1 
ATOM   5669  C  CA  . PHE C 1 216 ? 65.099  112.962 41.514  1.00 35.04  ? 216 PHE C CA  1 
ATOM   5670  C  C   . PHE C 1 216 ? 65.041  111.470 41.819  1.00 38.30  ? 216 PHE C C   1 
ATOM   5671  O  O   . PHE C 1 216 ? 64.620  110.676 40.965  1.00 32.07  ? 216 PHE C O   1 
ATOM   5672  C  CB  . PHE C 1 216 ? 63.697  113.592 41.592  1.00 38.85  ? 216 PHE C CB  1 
ATOM   5673  C  CG  . PHE C 1 216 ? 63.025  113.397 42.928  1.00 43.68  ? 216 PHE C CG  1 
ATOM   5674  C  CD1 . PHE C 1 216 ? 62.483  112.160 43.288  1.00 38.79  ? 216 PHE C CD1 1 
ATOM   5675  C  CD2 . PHE C 1 216 ? 62.977  114.436 43.844  1.00 40.43  ? 216 PHE C CD2 1 
ATOM   5676  C  CE1 . PHE C 1 216 ? 61.893  111.975 44.518  1.00 39.20  ? 216 PHE C CE1 1 
ATOM   5677  C  CE2 . PHE C 1 216 ? 62.378  114.259 45.085  1.00 38.42  ? 216 PHE C CE2 1 
ATOM   5678  C  CZ  . PHE C 1 216 ? 61.832  113.034 45.417  1.00 37.38  ? 216 PHE C CZ  1 
ATOM   5679  N  N   . LEU C 1 217 ? 65.436  111.090 43.036  1.00 37.61  ? 217 LEU C N   1 
ATOM   5680  C  CA  . LEU C 1 217 ? 65.443  109.667 43.356  1.00 33.12  ? 217 LEU C CA  1 
ATOM   5681  C  C   . LEU C 1 217 ? 65.734  109.456 44.832  1.00 31.07  ? 217 LEU C C   1 
ATOM   5682  O  O   . LEU C 1 217 ? 66.379  110.285 45.482  1.00 35.31  ? 217 LEU C O   1 
ATOM   5683  C  CB  . LEU C 1 217 ? 66.469  108.903 42.507  1.00 29.15  ? 217 LEU C CB  1 
ATOM   5684  C  CG  . LEU C 1 217 ? 67.945  109.050 42.861  1.00 28.39  ? 217 LEU C CG  1 
ATOM   5685  C  CD1 . LEU C 1 217 ? 68.759  108.273 41.838  1.00 29.59  ? 217 LEU C CD1 1 
ATOM   5686  C  CD2 . LEU C 1 217 ? 68.383  110.513 42.912  1.00 31.09  ? 217 LEU C CD2 1 
ATOM   5687  N  N   . ALA C 1 218 ? 65.254  108.323 45.345  1.00 26.62  ? 218 ALA C N   1 
ATOM   5688  C  CA  . ALA C 1 218 ? 65.529  107.953 46.719  1.00 23.67  ? 218 ALA C CA  1 
ATOM   5689  C  C   . ALA C 1 218 ? 66.880  107.258 46.850  1.00 27.02  ? 218 ALA C C   1 
ATOM   5690  O  O   . ALA C 1 218 ? 67.597  107.494 47.826  1.00 25.51  ? 218 ALA C O   1 
ATOM   5691  C  CB  . ALA C 1 218 ? 64.404  107.065 47.253  1.00 27.31  ? 218 ALA C CB  1 
ATOM   5692  N  N   . SER C 1 219 ? 67.250  106.419 45.880  1.00 21.49  ? 219 SER C N   1 
ATOM   5693  C  CA  . SER C 1 219 ? 68.462  105.617 45.996  1.00 26.39  ? 219 SER C CA  1 
ATOM   5694  C  C   . SER C 1 219 ? 69.085  105.398 44.621  1.00 24.67  ? 219 SER C C   1 
ATOM   5695  O  O   . SER C 1 219 ? 68.452  104.827 43.727  1.00 25.15  ? 219 SER C O   1 
ATOM   5696  C  CB  . SER C 1 219 ? 68.157  104.281 46.675  1.00 23.15  ? 219 SER C CB  1 
ATOM   5697  O  OG  . SER C 1 219 ? 69.257  103.391 46.556  1.00 25.27  ? 219 SER C OG  1 
ATOM   5698  N  N   . THR C 1 220 ? 70.334  105.834 44.451  1.00 24.68  ? 220 THR C N   1 
ATOM   5699  C  CA  . THR C 1 220 ? 70.981  105.662 43.151  1.00 23.83  ? 220 THR C CA  1 
ATOM   5700  C  C   . THR C 1 220 ? 71.389  104.212 42.936  1.00 23.89  ? 220 THR C C   1 
ATOM   5701  O  O   . THR C 1 220 ? 71.264  103.682 41.821  1.00 22.95  ? 220 THR C O   1 
ATOM   5702  C  CB  . THR C 1 220 ? 72.199  106.590 43.029  1.00 26.43  ? 220 THR C CB  1 
ATOM   5703  O  OG1 . THR C 1 220 ? 71.877  107.882 43.560  1.00 26.36  ? 220 THR C OG1 1 
ATOM   5704  C  CG2 . THR C 1 220 ? 72.601  106.757 41.567  1.00 24.20  ? 220 THR C CG2 1 
ATOM   5705  N  N   . VAL C 1 221 ? 71.874  103.555 43.993  1.00 22.66  ? 221 VAL C N   1 
ATOM   5706  C  CA  . VAL C 1 221 ? 72.224  102.139 43.903  1.00 21.98  ? 221 VAL C CA  1 
ATOM   5707  C  C   . VAL C 1 221 ? 71.018  101.324 43.426  1.00 23.97  ? 221 VAL C C   1 
ATOM   5708  O  O   . VAL C 1 221 ? 71.108  100.566 42.454  1.00 22.36  ? 221 VAL C O   1 
ATOM   5709  C  CB  . VAL C 1 221 ? 72.769  101.637 45.255  1.00 23.66  ? 221 VAL C CB  1 
ATOM   5710  C  CG1 . VAL C 1 221 ? 72.911  100.118 45.281  1.00 21.07  ? 221 VAL C CG1 1 
ATOM   5711  C  CG2 . VAL C 1 221 ? 74.101  102.330 45.590  1.00 20.13  ? 221 VAL C CG2 1 
ATOM   5712  N  N   . ASP C 1 222 ? 69.861  101.495 44.080  1.00 23.05  ? 222 ASP C N   1 
ATOM   5713  C  CA  . ASP C 1 222 ? 68.662  100.764 43.663  1.00 19.95  ? 222 ASP C CA  1 
ATOM   5714  C  C   . ASP C 1 222 ? 68.218  101.154 42.252  1.00 20.00  ? 222 ASP C C   1 
ATOM   5715  O  O   . ASP C 1 222 ? 67.834  100.288 41.460  1.00 20.17  ? 222 ASP C O   1 
ATOM   5716  C  CB  . ASP C 1 222 ? 67.518  101.009 44.655  1.00 20.86  ? 222 ASP C CB  1 
ATOM   5717  C  CG  . ASP C 1 222 ? 67.722  100.289 45.978  1.00 23.42  ? 222 ASP C CG  1 
ATOM   5718  O  OD1 . ASP C 1 222 ? 68.516  99.325  46.025  1.00 28.28  ? 222 ASP C OD1 1 
ATOM   5719  O  OD2 . ASP C 1 222 ? 67.076  100.690 46.968  1.00 26.04  ? 222 ASP C OD2 1 
ATOM   5720  N  N   . ALA C 1 223 ? 68.259  102.454 41.925  1.00 21.76  ? 223 ALA C N   1 
ATOM   5721  C  CA  . ALA C 1 223 ? 67.793  102.932 40.620  1.00 21.97  ? 223 ALA C CA  1 
ATOM   5722  C  C   . ALA C 1 223 ? 68.564  102.296 39.467  1.00 22.90  ? 223 ALA C C   1 
ATOM   5723  O  O   . ALA C 1 223 ? 67.961  101.855 38.480  1.00 22.69  ? 223 ALA C O   1 
ATOM   5724  C  CB  . ALA C 1 223 ? 67.890  104.458 40.535  1.00 18.30  ? 223 ALA C CB  1 
ATOM   5725  N  N   . VAL C 1 224 ? 69.895  102.234 39.565  1.00 22.83  ? 224 VAL C N   1 
ATOM   5726  C  CA  . VAL C 1 224 ? 70.650  101.655 38.456  1.00 20.97  ? 224 VAL C CA  1 
ATOM   5727  C  C   . VAL C 1 224 ? 70.497  100.140 38.428  1.00 24.60  ? 224 VAL C C   1 
ATOM   5728  O  O   . VAL C 1 224 ? 70.455  99.539  37.347  1.00 20.98  ? 224 VAL C O   1 
ATOM   5729  C  CB  . VAL C 1 224 ? 72.135  102.075 38.502  1.00 23.52  ? 224 VAL C CB  1 
ATOM   5730  C  CG1 . VAL C 1 224 ? 72.243  103.578 38.370  1.00 22.61  ? 224 VAL C CG1 1 
ATOM   5731  C  CG2 . VAL C 1 224 ? 72.841  101.592 39.782  1.00 24.46  ? 224 VAL C CG2 1 
ATOM   5732  N  N   . ARG C 1 225 ? 70.387  99.488  39.594  1.00 23.99  ? 225 ARG C N   1 
ATOM   5733  C  CA  . ARG C 1 225 ? 70.208  98.040  39.552  1.00 23.82  ? 225 ARG C CA  1 
ATOM   5734  C  C   . ARG C 1 225 ? 68.847  97.678  38.989  1.00 24.31  ? 225 ARG C C   1 
ATOM   5735  O  O   . ARG C 1 225 ? 68.713  96.655  38.301  1.00 22.45  ? 225 ARG C O   1 
ATOM   5736  C  CB  . ARG C 1 225 ? 70.398  97.427  40.932  1.00 24.36  ? 225 ARG C CB  1 
ATOM   5737  C  CG  . ARG C 1 225 ? 71.824  97.486  41.358  1.00 21.44  ? 225 ARG C CG  1 
ATOM   5738  C  CD  . ARG C 1 225 ? 72.023  97.113  42.797  1.00 25.25  ? 225 ARG C CD  1 
ATOM   5739  N  NE  . ARG C 1 225 ? 73.411  97.350  43.171  1.00 23.42  ? 225 ARG C NE  1 
ATOM   5740  C  CZ  . ARG C 1 225 ? 73.950  96.960  44.313  1.00 28.82  ? 225 ARG C CZ  1 
ATOM   5741  N  NH1 . ARG C 1 225 ? 73.232  96.320  45.226  1.00 25.93  ? 225 ARG C NH1 1 
ATOM   5742  N  NH2 . ARG C 1 225 ? 75.232  97.241  44.556  1.00 23.56  ? 225 ARG C NH2 1 
ATOM   5743  N  N   . SER C 1 226 ? 67.841  98.517  39.262  1.00 23.01  ? 226 SER C N   1 
ATOM   5744  C  CA  . SER C 1 226 ? 66.505  98.332  38.709  1.00 20.60  ? 226 SER C CA  1 
ATOM   5745  C  C   . SER C 1 226 ? 66.489  98.509  37.194  1.00 23.71  ? 226 SER C C   1 
ATOM   5746  O  O   . SER C 1 226 ? 65.738  97.816  36.508  1.00 24.24  ? 226 SER C O   1 
ATOM   5747  C  CB  . SER C 1 226 ? 65.544  99.316  39.373  1.00 22.60  ? 226 SER C CB  1 
ATOM   5748  O  OG  . SER C 1 226 ? 65.182  98.884  40.687  1.00 22.32  ? 226 SER C OG  1 
ATOM   5749  N  N   . VAL C 1 227 ? 67.314  99.416  36.653  1.00 23.59  ? 227 VAL C N   1 
ATOM   5750  C  CA  . VAL C 1 227 ? 67.409  99.544  35.203  1.00 19.91  ? 227 VAL C CA  1 
ATOM   5751  C  C   . VAL C 1 227 ? 68.010  98.275  34.600  1.00 24.17  ? 227 VAL C C   1 
ATOM   5752  O  O   . VAL C 1 227 ? 67.536  97.767  33.573  1.00 23.81  ? 227 VAL C O   1 
ATOM   5753  C  CB  . VAL C 1 227 ? 68.211  100.807 34.835  1.00 28.08  ? 227 VAL C CB  1 
ATOM   5754  C  CG1 . VAL C 1 227 ? 68.577  100.815 33.345  1.00 27.26  ? 227 VAL C CG1 1 
ATOM   5755  C  CG2 . VAL C 1 227 ? 67.425  102.056 35.201  1.00 24.45  ? 227 VAL C CG2 1 
ATOM   5756  N  N   . ARG C 1 228 ? 69.024  97.707  35.258  1.00 22.25  ? 228 ARG C N   1 
ATOM   5757  C  CA  . ARG C 1 228 ? 69.636  96.493  34.736  1.00 23.91  ? 228 ARG C CA  1 
ATOM   5758  C  C   . ARG C 1 228 ? 68.696  95.304  34.854  1.00 26.62  ? 228 ARG C C   1 
ATOM   5759  O  O   . ARG C 1 228 ? 68.691  94.428  33.977  1.00 28.95  ? 228 ARG C O   1 
ATOM   5760  C  CB  . ARG C 1 228 ? 70.959  96.230  35.451  1.00 23.89  ? 228 ARG C CB  1 
ATOM   5761  C  CG  . ARG C 1 228 ? 72.009  97.241  35.014  1.00 31.57  ? 228 ARG C CG  1 
ATOM   5762  C  CD  . ARG C 1 228 ? 73.417  96.708  35.093  1.00 32.67  ? 228 ARG C CD  1 
ATOM   5763  N  NE  . ARG C 1 228 ? 74.355  97.641  34.484  1.00 31.00  ? 228 ARG C NE  1 
ATOM   5764  C  CZ  . ARG C 1 228 ? 75.662  97.442  34.411  1.00 33.72  ? 228 ARG C CZ  1 
ATOM   5765  N  NH1 . ARG C 1 228 ? 76.229  96.360  34.932  1.00 28.18  ? 228 ARG C NH1 1 
ATOM   5766  N  NH2 . ARG C 1 228 ? 76.419  98.341  33.784  1.00 35.39  ? 228 ARG C NH2 1 
ATOM   5767  N  N   . LYS C 1 229 ? 67.887  95.268  35.915  1.00 21.32  ? 229 LYS C N   1 
ATOM   5768  C  CA  . LYS C 1 229 ? 66.830  94.268  36.019  1.00 23.97  ? 229 LYS C CA  1 
ATOM   5769  C  C   . LYS C 1 229 ? 65.851  94.376  34.852  1.00 21.60  ? 229 LYS C C   1 
ATOM   5770  O  O   . LYS C 1 229 ? 65.401  93.360  34.316  1.00 25.16  ? 229 LYS C O   1 
ATOM   5771  C  CB  . LYS C 1 229 ? 66.101  94.430  37.360  1.00 25.42  ? 229 LYS C CB  1 
ATOM   5772  C  CG  . LYS C 1 229 ? 64.806  93.649  37.485  1.00 20.24  ? 229 LYS C CG  1 
ATOM   5773  C  CD  . LYS C 1 229 ? 64.261  93.766  38.915  1.00 24.05  ? 229 LYS C CD  1 
ATOM   5774  C  CE  . LYS C 1 229 ? 63.059  92.863  39.142  1.00 23.83  ? 229 LYS C CE  1 
ATOM   5775  N  NZ  . LYS C 1 229 ? 62.354  93.237  40.401  1.00 24.37  ? 229 LYS C NZ  1 
ATOM   5776  N  N   . LEU C 1 230 ? 65.506  95.603  34.448  1.00 21.28  ? 230 LEU C N   1 
ATOM   5777  C  CA  . LEU C 1 230 ? 64.677  95.783  33.261  1.00 25.12  ? 230 LEU C CA  1 
ATOM   5778  C  C   . LEU C 1 230 ? 65.425  95.378  31.991  1.00 28.15  ? 230 LEU C C   1 
ATOM   5779  O  O   . LEU C 1 230 ? 64.814  94.820  31.064  1.00 28.25  ? 230 LEU C O   1 
ATOM   5780  C  CB  . LEU C 1 230 ? 64.200  97.233  33.166  1.00 26.16  ? 230 LEU C CB  1 
ATOM   5781  C  CG  . LEU C 1 230 ? 63.156  97.612  34.223  1.00 24.41  ? 230 LEU C CG  1 
ATOM   5782  C  CD1 . LEU C 1 230 ? 62.579  99.005  33.961  1.00 24.20  ? 230 LEU C CD1 1 
ATOM   5783  C  CD2 . LEU C 1 230 ? 62.047  96.576  34.282  1.00 20.54  ? 230 LEU C CD2 1 
ATOM   5784  N  N   . HIS C 1 231 ? 66.739  95.653  31.926  1.00 26.09  ? 231 HIS C N   1 
ATOM   5785  C  CA  . HIS C 1 231 ? 67.534  95.224  30.773  1.00 28.92  ? 231 HIS C CA  1 
ATOM   5786  C  C   . HIS C 1 231 ? 67.367  93.731  30.554  1.00 28.64  ? 231 HIS C C   1 
ATOM   5787  O  O   . HIS C 1 231 ? 67.038  93.291  29.451  1.00 27.66  ? 231 HIS C O   1 
ATOM   5788  C  CB  . HIS C 1 231 ? 69.023  95.554  30.956  1.00 26.03  ? 231 HIS C CB  1 
ATOM   5789  C  CG  . HIS C 1 231 ? 69.369  96.999  30.757  1.00 28.92  ? 231 HIS C CG  1 
ATOM   5790  N  ND1 . HIS C 1 231 ? 70.604  97.517  31.090  1.00 32.55  ? 231 HIS C ND1 1 
ATOM   5791  C  CD2 . HIS C 1 231 ? 68.649  98.035  30.263  1.00 29.59  ? 231 HIS C CD2 1 
ATOM   5792  C  CE1 . HIS C 1 231 ? 70.629  98.810  30.812  1.00 33.72  ? 231 HIS C CE1 1 
ATOM   5793  N  NE2 . HIS C 1 231 ? 69.454  99.150  30.311  1.00 34.12  ? 231 HIS C NE2 1 
ATOM   5794  N  N   . ALA C 1 232 ? 67.550  92.944  31.621  1.00 29.07  ? 232 ALA C N   1 
ATOM   5795  C  CA  . ALA C 1 232 ? 67.399  91.499  31.527  1.00 26.45  ? 232 ALA C CA  1 
ATOM   5796  C  C   . ALA C 1 232 ? 65.979  91.117  31.132  1.00 29.33  ? 232 ALA C C   1 
ATOM   5797  O  O   . ALA C 1 232 ? 65.773  90.158  30.378  1.00 28.65  ? 232 ALA C O   1 
ATOM   5798  C  CB  . ALA C 1 232 ? 67.778  90.838  32.855  1.00 21.72  ? 232 ALA C CB  1 
ATOM   5799  N  N   . LEU C 1 233 ? 64.980  91.830  31.654  1.00 28.88  ? 233 LEU C N   1 
ATOM   5800  C  CA  . LEU C 1 233 ? 63.603  91.447  31.361  1.00 28.54  ? 233 LEU C CA  1 
ATOM   5801  C  C   . LEU C 1 233 ? 63.263  91.726  29.897  1.00 25.46  ? 233 LEU C C   1 
ATOM   5802  O  O   . LEU C 1 233 ? 62.716  90.861  29.203  1.00 24.92  ? 233 LEU C O   1 
ATOM   5803  C  CB  . LEU C 1 233 ? 62.636  92.166  32.304  1.00 24.07  ? 233 LEU C CB  1 
ATOM   5804  C  CG  . LEU C 1 233 ? 61.142  91.895  32.078  1.00 24.48  ? 233 LEU C CG  1 
ATOM   5805  C  CD1 . LEU C 1 233 ? 60.819  90.441  32.343  1.00 24.83  ? 233 LEU C CD1 1 
ATOM   5806  C  CD2 . LEU C 1 233 ? 60.273  92.790  32.966  1.00 26.64  ? 233 LEU C CD2 1 
ATOM   5807  N  N   . ALA C 1 234 ? 63.584  92.934  29.415  1.00 27.44  ? 234 ALA C N   1 
ATOM   5808  C  CA  . ALA C 1 234 ? 63.447  93.253  27.993  1.00 29.40  ? 234 ALA C CA  1 
ATOM   5809  C  C   . ALA C 1 234 ? 64.136  92.215  27.119  1.00 30.26  ? 234 ALA C C   1 
ATOM   5810  O  O   . ALA C 1 234 ? 63.560  91.735  26.134  1.00 28.91  ? 234 ALA C O   1 
ATOM   5811  C  CB  . ALA C 1 234 ? 64.027  94.637  27.696  1.00 26.14  ? 234 ALA C CB  1 
ATOM   5812  N  N   . GLU C 1 235 ? 65.377  91.853  27.473  1.00 29.11  ? 235 GLU C N   1 
ATOM   5813  C  CA  . GLU C 1 235 ? 66.136  90.920  26.645  1.00 30.25  ? 235 GLU C CA  1 
ATOM   5814  C  C   . GLU C 1 235 ? 65.519  89.529  26.675  1.00 33.82  ? 235 GLU C C   1 
ATOM   5815  O  O   . GLU C 1 235 ? 65.513  88.824  25.660  1.00 33.45  ? 235 GLU C O   1 
ATOM   5816  C  CB  . GLU C 1 235 ? 67.596  90.862  27.091  1.00 33.09  ? 235 GLU C CB  1 
ATOM   5817  C  CG  . GLU C 1 235 ? 68.513  90.063  26.139  1.00 32.77  ? 235 GLU C CG  1 
ATOM   5818  C  CD  . GLU C 1 235 ? 68.492  88.556  26.390  1.00 36.67  ? 235 GLU C CD  1 
ATOM   5819  O  OE1 . GLU C 1 235 ? 68.041  88.132  27.474  1.00 30.50  ? 235 GLU C OE1 1 
ATOM   5820  O  OE2 . GLU C 1 235 ? 68.934  87.793  25.500  1.00 37.37  ? 235 GLU C OE2 1 
ATOM   5821  N  N   . LYS C 1 236 ? 64.991  89.114  27.825  1.00 31.18  ? 236 LYS C N   1 
ATOM   5822  C  CA  . LYS C 1 236 ? 64.392  87.789  27.897  1.00 27.41  ? 236 LYS C CA  1 
ATOM   5823  C  C   . LYS C 1 236 ? 63.077  87.748  27.131  1.00 31.40  ? 236 LYS C C   1 
ATOM   5824  O  O   . LYS C 1 236 ? 62.811  86.794  26.391  1.00 33.46  ? 236 LYS C O   1 
ATOM   5825  C  CB  . LYS C 1 236 ? 64.192  87.383  29.359  1.00 28.20  ? 236 LYS C CB  1 
ATOM   5826  C  CG  . LYS C 1 236 ? 63.144  86.297  29.607  1.00 29.59  ? 236 LYS C CG  1 
ATOM   5827  C  CD  . LYS C 1 236 ? 63.093  85.923  31.094  1.00 26.99  ? 236 LYS C CD  1 
ATOM   5828  C  CE  . LYS C 1 236 ? 61.841  85.135  31.415  1.00 30.60  ? 236 LYS C CE  1 
ATOM   5829  N  NZ  . LYS C 1 236 ? 61.770  84.676  32.850  1.00 29.62  ? 236 LYS C NZ  1 
ATOM   5830  N  N   . THR C 1 237 ? 62.248  88.777  27.278  1.00 29.29  ? 237 THR C N   1 
ATOM   5831  C  CA  . THR C 1 237 ? 60.896  88.696  26.748  1.00 30.94  ? 237 THR C CA  1 
ATOM   5832  C  C   . THR C 1 237 ? 60.774  89.271  25.350  1.00 29.23  ? 237 THR C C   1 
ATOM   5833  O  O   . THR C 1 237 ? 59.798  88.968  24.666  1.00 27.75  ? 237 THR C O   1 
ATOM   5834  C  CB  . THR C 1 237 ? 59.896  89.434  27.655  1.00 27.77  ? 237 THR C CB  1 
ATOM   5835  O  OG1 . THR C 1 237 ? 60.276  90.811  27.766  1.00 27.33  ? 237 THR C OG1 1 
ATOM   5836  C  CG2 . THR C 1 237 ? 59.833  88.799  29.057  1.00 26.45  ? 237 THR C CG2 1 
ATOM   5837  N  N   . GLY C 1 238 ? 61.726  90.097  24.924  1.00 29.85  ? 238 GLY C N   1 
ATOM   5838  C  CA  . GLY C 1 238 ? 61.560  90.868  23.704  1.00 27.65  ? 238 GLY C CA  1 
ATOM   5839  C  C   . GLY C 1 238 ? 60.546  91.986  23.818  1.00 32.40  ? 238 GLY C C   1 
ATOM   5840  O  O   . GLY C 1 238 ? 59.939  92.366  22.812  1.00 30.18  ? 238 GLY C O   1 
ATOM   5841  N  N   . ALA C 1 239 ? 60.345  92.532  25.019  1.00 29.22  ? 239 ALA C N   1 
ATOM   5842  C  CA  . ALA C 1 239 ? 59.244  93.466  25.222  1.00 29.21  ? 239 ALA C CA  1 
ATOM   5843  C  C   . ALA C 1 239 ? 59.478  94.773  24.478  1.00 30.62  ? 239 ALA C C   1 
ATOM   5844  O  O   . ALA C 1 239 ? 60.616  95.180  24.229  1.00 28.45  ? 239 ALA C O   1 
ATOM   5845  C  CB  . ALA C 1 239 ? 59.038  93.769  26.702  1.00 28.20  ? 239 ALA C CB  1 
ATOM   5846  N  N   . LEU C 1 240 ? 58.369  95.417  24.109  1.00 26.96  ? 240 LEU C N   1 
ATOM   5847  C  CA  . LEU C 1 240 ? 58.379  96.813  23.705  1.00 30.24  ? 240 LEU C CA  1 
ATOM   5848  C  C   . LEU C 1 240 ? 58.536  97.681  24.953  1.00 29.47  ? 240 LEU C C   1 
ATOM   5849  O  O   . LEU C 1 240 ? 57.675  97.655  25.845  1.00 29.43  ? 240 LEU C O   1 
ATOM   5850  C  CB  . LEU C 1 240 ? 57.095  97.151  22.951  1.00 27.78  ? 240 LEU C CB  1 
ATOM   5851  C  CG  . LEU C 1 240 ? 56.895  98.613  22.522  1.00 32.57  ? 240 LEU C CG  1 
ATOM   5852  C  CD1 . LEU C 1 240 ? 57.925  99.017  21.472  1.00 31.80  ? 240 LEU C CD1 1 
ATOM   5853  C  CD2 . LEU C 1 240 ? 55.488  98.819  21.969  1.00 28.07  ? 240 LEU C CD2 1 
ATOM   5854  N  N   . VAL C 1 241 ? 59.629  98.441  25.017  1.00 25.96  ? 241 VAL C N   1 
ATOM   5855  C  CA  . VAL C 1 241 ? 59.968  99.245  26.193  1.00 29.87  ? 241 VAL C CA  1 
ATOM   5856  C  C   . VAL C 1 241 ? 59.390  100.649 26.035  1.00 29.61  ? 241 VAL C C   1 
ATOM   5857  O  O   . VAL C 1 241 ? 59.691  101.350 25.064  1.00 32.44  ? 241 VAL C O   1 
ATOM   5858  C  CB  . VAL C 1 241 ? 61.494  99.304  26.404  1.00 31.49  ? 241 VAL C CB  1 
ATOM   5859  C  CG1 . VAL C 1 241 ? 61.827  100.035 27.671  1.00 25.77  ? 241 VAL C CG1 1 
ATOM   5860  C  CG2 . VAL C 1 241 ? 62.119  97.897  26.432  1.00 26.32  ? 241 VAL C CG2 1 
ATOM   5861  N  N   . VAL C 1 242 ? 58.591  101.080 27.006  1.00 30.32  ? 242 VAL C N   1 
ATOM   5862  C  CA  . VAL C 1 242 ? 58.017  102.419 27.025  1.00 26.12  ? 242 VAL C CA  1 
ATOM   5863  C  C   . VAL C 1 242 ? 58.641  103.187 28.184  1.00 31.94  ? 242 VAL C C   1 
ATOM   5864  O  O   . VAL C 1 242 ? 58.459  102.819 29.352  1.00 29.53  ? 242 VAL C O   1 
ATOM   5865  C  CB  . VAL C 1 242 ? 56.488  102.370 27.151  1.00 31.77  ? 242 VAL C CB  1 
ATOM   5866  C  CG1 . VAL C 1 242 ? 55.885  103.749 26.930  1.00 32.84  ? 242 VAL C CG1 1 
ATOM   5867  C  CG2 . VAL C 1 242 ? 55.923  101.387 26.153  1.00 30.75  ? 242 VAL C CG2 1 
ATOM   5868  N  N   . TYR C 1 243 ? 59.379  104.248 27.861  1.00 32.88  ? 243 TYR C N   1 
ATOM   5869  C  CA  . TYR C 1 243 ? 60.031  105.097 28.850  1.00 26.99  ? 243 TYR C CA  1 
ATOM   5870  C  C   . TYR C 1 243 ? 59.004  106.022 29.494  1.00 32.90  ? 243 TYR C C   1 
ATOM   5871  O  O   . TYR C 1 243 ? 57.977  106.353 28.896  1.00 31.89  ? 243 TYR C O   1 
ATOM   5872  C  CB  . TYR C 1 243 ? 61.169  105.894 28.189  1.00 32.23  ? 243 TYR C CB  1 
ATOM   5873  C  CG  . TYR C 1 243 ? 62.006  104.997 27.305  1.00 32.18  ? 243 TYR C CG  1 
ATOM   5874  C  CD1 . TYR C 1 243 ? 62.987  104.173 27.852  1.00 30.96  ? 243 TYR C CD1 1 
ATOM   5875  C  CD2 . TYR C 1 243 ? 61.749  104.892 25.935  1.00 37.58  ? 243 TYR C CD2 1 
ATOM   5876  C  CE1 . TYR C 1 243 ? 63.725  103.297 27.058  1.00 27.97  ? 243 TYR C CE1 1 
ATOM   5877  C  CE2 . TYR C 1 243 ? 62.477  104.015 25.126  1.00 33.38  ? 243 TYR C CE2 1 
ATOM   5878  C  CZ  . TYR C 1 243 ? 63.465  103.225 25.699  1.00 33.88  ? 243 TYR C CZ  1 
ATOM   5879  O  OH  . TYR C 1 243 ? 64.189  102.370 24.902  1.00 37.16  ? 243 TYR C OH  1 
ATOM   5880  N  N   . GLY C 1 244 ? 59.283  106.434 30.734  1.00 30.51  ? 244 GLY C N   1 
ATOM   5881  C  CA  . GLY C 1 244 ? 58.259  107.095 31.528  1.00 29.52  ? 244 GLY C CA  1 
ATOM   5882  C  C   . GLY C 1 244 ? 58.035  108.568 31.235  1.00 34.51  ? 244 GLY C C   1 
ATOM   5883  O  O   . GLY C 1 244 ? 56.920  109.065 31.416  1.00 33.20  ? 244 GLY C O   1 
ATOM   5884  N  N   . HIS C 1 245 ? 59.070  109.292 30.808  1.00 32.48  ? 245 HIS C N   1 
ATOM   5885  C  CA  . HIS C 1 245 ? 58.971  110.745 30.613  1.00 37.72  ? 245 HIS C CA  1 
ATOM   5886  C  C   . HIS C 1 245 ? 59.924  111.193 29.509  1.00 37.82  ? 245 HIS C C   1 
ATOM   5887  O  O   . HIS C 1 245 ? 60.807  112.027 29.717  1.00 38.19  ? 245 HIS C O   1 
ATOM   5888  C  CB  . HIS C 1 245 ? 59.295  111.509 31.897  1.00 29.29  ? 245 HIS C CB  1 
ATOM   5889  C  CG  . HIS C 1 245 ? 58.278  111.362 32.976  1.00 35.34  ? 245 HIS C CG  1 
ATOM   5890  N  ND1 . HIS C 1 245 ? 57.004  111.879 32.875  1.00 34.36  ? 245 HIS C ND1 1 
ATOM   5891  C  CD2 . HIS C 1 245 ? 58.354  110.779 34.197  1.00 32.39  ? 245 HIS C CD2 1 
ATOM   5892  C  CE1 . HIS C 1 245 ? 56.335  111.613 33.984  1.00 32.40  ? 245 HIS C CE1 1 
ATOM   5893  N  NE2 . HIS C 1 245 ? 57.131  110.945 34.801  1.00 32.55  ? 245 HIS C NE2 1 
ATOM   5894  N  N   . ASP C 1 246 ? 59.773  110.643 28.308  1.00 34.95  ? 246 ASP C N   1 
ATOM   5895  C  CA  . ASP C 1 246 ? 60.742  110.911 27.256  1.00 34.91  ? 246 ASP C CA  1 
ATOM   5896  C  C   . ASP C 1 246 ? 60.088  111.712 26.139  1.00 39.78  ? 246 ASP C C   1 
ATOM   5897  O  O   . ASP C 1 246 ? 59.279  111.155 25.381  1.00 40.88  ? 246 ASP C O   1 
ATOM   5898  C  CB  . ASP C 1 246 ? 61.320  109.602 26.719  1.00 36.51  ? 246 ASP C CB  1 
ATOM   5899  C  CG  . ASP C 1 246 ? 62.513  109.822 25.786  1.00 40.19  ? 246 ASP C CG  1 
ATOM   5900  O  OD1 . ASP C 1 246 ? 62.494  110.802 25.013  1.00 45.24  ? 246 ASP C OD1 1 
ATOM   5901  O  OD2 . ASP C 1 246 ? 63.467  109.014 25.817  1.00 38.18  ? 246 ASP C OD2 1 
ATOM   5902  N  N   . PRO C 1 247 ? 60.426  112.996 25.975  1.00 39.67  ? 247 PRO C N   1 
ATOM   5903  C  CA  . PRO C 1 247 ? 59.753  113.806 24.940  1.00 41.27  ? 247 PRO C CA  1 
ATOM   5904  C  C   . PRO C 1 247 ? 60.089  113.392 23.515  1.00 43.23  ? 247 PRO C C   1 
ATOM   5905  O  O   . PRO C 1 247 ? 59.265  113.621 22.623  1.00 44.65  ? 247 PRO C O   1 
ATOM   5906  C  CB  . PRO C 1 247 ? 60.225  115.239 25.229  1.00 41.29  ? 247 PRO C CB  1 
ATOM   5907  C  CG  . PRO C 1 247 ? 61.095  115.170 26.446  1.00 43.82  ? 247 PRO C CG  1 
ATOM   5908  C  CD  . PRO C 1 247 ? 61.474  113.741 26.685  1.00 40.90  ? 247 PRO C CD  1 
ATOM   5909  N  N   . GLU C 1 248 ? 61.253  112.775 23.267  1.00 42.57  ? 248 GLU C N   1 
ATOM   5910  C  CA  . GLU C 1 248 ? 61.548  112.286 21.922  1.00 44.41  ? 248 GLU C CA  1 
ATOM   5911  C  C   . GLU C 1 248 ? 60.905  110.931 21.648  1.00 43.54  ? 248 GLU C C   1 
ATOM   5912  O  O   . GLU C 1 248 ? 60.406  110.693 20.541  1.00 41.42  ? 248 GLU C O   1 
ATOM   5913  C  CB  . GLU C 1 248 ? 63.061  112.195 21.700  1.00 48.26  ? 248 GLU C CB  1 
ATOM   5914  C  CG  . GLU C 1 248 ? 63.852  113.377 22.249  1.00 57.87  ? 248 GLU C CG  1 
ATOM   5915  C  CD  . GLU C 1 248 ? 65.360  113.159 22.176  1.00 62.43  ? 248 GLU C CD  1 
ATOM   5916  O  OE1 . GLU C 1 248 ? 66.099  114.158 22.064  1.00 70.38  ? 248 GLU C OE1 1 
ATOM   5917  O  OE2 . GLU C 1 248 ? 65.807  111.994 22.247  1.00 66.33  ? 248 GLU C OE2 1 
ATOM   5918  N  N   . ALA C 1 249 ? 60.912  110.026 22.629  1.00 40.09  ? 249 ALA C N   1 
ATOM   5919  C  CA  . ALA C 1 249 ? 60.417  108.672 22.385  1.00 38.56  ? 249 ALA C CA  1 
ATOM   5920  C  C   . ALA C 1 249 ? 58.890  108.606 22.396  1.00 39.61  ? 249 ALA C C   1 
ATOM   5921  O  O   . ALA C 1 249 ? 58.287  107.848 21.624  1.00 40.15  ? 249 ALA C O   1 
ATOM   5922  C  CB  . ALA C 1 249 ? 60.999  107.716 23.424  1.00 38.18  ? 249 ALA C CB  1 
ATOM   5923  N  N   . TRP C 1 250 ? 58.258  109.399 23.255  1.00 40.87  ? 250 TRP C N   1 
ATOM   5924  C  CA  . TRP C 1 250 ? 56.813  109.303 23.454  1.00 37.58  ? 250 TRP C CA  1 
ATOM   5925  C  C   . TRP C 1 250 ? 55.991  109.483 22.177  1.00 41.84  ? 250 TRP C C   1 
ATOM   5926  O  O   . TRP C 1 250 ? 55.032  108.710 21.988  1.00 40.28  ? 250 TRP C O   1 
ATOM   5927  C  CB  . TRP C 1 250 ? 56.407  110.311 24.537  1.00 34.97  ? 250 TRP C CB  1 
ATOM   5928  C  CG  . TRP C 1 250 ? 54.975  110.300 24.963  1.00 36.68  ? 250 TRP C CG  1 
ATOM   5929  C  CD1 . TRP C 1 250 ? 54.079  111.321 24.834  1.00 37.48  ? 250 TRP C CD1 1 
ATOM   5930  C  CD2 . TRP C 1 250 ? 54.278  109.237 25.641  1.00 36.39  ? 250 TRP C CD2 1 
ATOM   5931  N  NE1 . TRP C 1 250 ? 52.860  110.953 25.364  1.00 37.70  ? 250 TRP C NE1 1 
ATOM   5932  C  CE2 . TRP C 1 250 ? 52.957  109.680 25.865  1.00 35.74  ? 250 TRP C CE2 1 
ATOM   5933  C  CE3 . TRP C 1 250 ? 54.635  107.947 26.052  1.00 34.21  ? 250 TRP C CE3 1 
ATOM   5934  C  CZ2 . TRP C 1 250 ? 51.995  108.880 26.489  1.00 35.16  ? 250 TRP C CZ2 1 
ATOM   5935  C  CZ3 . TRP C 1 250 ? 53.683  107.160 26.672  1.00 31.91  ? 250 TRP C CZ3 1 
ATOM   5936  C  CH2 . TRP C 1 250 ? 52.376  107.624 26.877  1.00 34.65  ? 250 TRP C CH2 1 
ATOM   5937  N  N   . PRO C 1 251 ? 56.292  110.432 21.271  1.00 44.79  ? 251 PRO C N   1 
ATOM   5938  C  CA  . PRO C 1 251 ? 55.480  110.542 20.041  1.00 38.48  ? 251 PRO C CA  1 
ATOM   5939  C  C   . PRO C 1 251 ? 55.610  109.338 19.122  1.00 39.00  ? 251 PRO C C   1 
ATOM   5940  O  O   . PRO C 1 251 ? 54.742  109.132 18.269  1.00 38.91  ? 251 PRO C O   1 
ATOM   5941  C  CB  . PRO C 1 251 ? 56.024  111.811 19.363  1.00 37.37  ? 251 PRO C CB  1 
ATOM   5942  C  CG  . PRO C 1 251 ? 56.764  112.539 20.426  1.00 40.90  ? 251 PRO C CG  1 
ATOM   5943  C  CD  . PRO C 1 251 ? 57.337  111.473 21.308  1.00 40.51  ? 251 PRO C CD  1 
ATOM   5944  N  N   . THR C 1 252 ? 56.659  108.537 19.263  1.00 38.31  ? 252 THR C N   1 
ATOM   5945  C  CA  . THR C 1 252 ? 56.817  107.377 18.405  1.00 37.58  ? 252 THR C CA  1 
ATOM   5946  C  C   . THR C 1 252 ? 55.929  106.214 18.820  1.00 42.32  ? 252 THR C C   1 
ATOM   5947  O  O   . THR C 1 252 ? 55.788  105.254 18.055  1.00 42.01  ? 252 THR C O   1 
ATOM   5948  C  CB  . THR C 1 252 ? 58.276  106.934 18.402  1.00 42.58  ? 252 THR C CB  1 
ATOM   5949  O  OG1 . THR C 1 252 ? 58.527  106.099 19.542  1.00 47.00  ? 252 THR C OG1 1 
ATOM   5950  C  CG2 . THR C 1 252 ? 59.170  108.167 18.479  1.00 39.92  ? 252 THR C CG2 1 
ATOM   5951  N  N   . PHE C 1 253 ? 55.330  106.265 20.002  1.00 43.14  ? 253 PHE C N   1 
ATOM   5952  C  CA  . PHE C 1 253 ? 54.458  105.172 20.400  1.00 44.73  ? 253 PHE C CA  1 
ATOM   5953  C  C   . PHE C 1 253 ? 53.051  105.434 19.891  1.00 38.91  ? 253 PHE C C   1 
ATOM   5954  O  O   . PHE C 1 253 ? 52.731  106.522 19.406  1.00 38.04  ? 253 PHE C O   1 
ATOM   5955  C  CB  . PHE C 1 253 ? 54.445  104.999 21.923  1.00 43.06  ? 253 PHE C CB  1 
ATOM   5956  C  CG  . PHE C 1 253 ? 55.780  104.655 22.502  1.00 38.89  ? 253 PHE C CG  1 
ATOM   5957  C  CD1 . PHE C 1 253 ? 56.368  103.432 22.243  1.00 41.44  ? 253 PHE C CD1 1 
ATOM   5958  C  CD2 . PHE C 1 253 ? 56.454  105.565 23.292  1.00 37.57  ? 253 PHE C CD2 1 
ATOM   5959  C  CE1 . PHE C 1 253 ? 57.604  103.127 22.764  1.00 37.07  ? 253 PHE C CE1 1 
ATOM   5960  C  CE2 . PHE C 1 253 ? 57.697  105.258 23.817  1.00 39.83  ? 253 PHE C CE2 1 
ATOM   5961  C  CZ  . PHE C 1 253 ? 58.268  104.044 23.553  1.00 35.02  ? 253 PHE C CZ  1 
ATOM   5962  N  N   . ARG C 1 254 ? 52.201  104.422 20.022  1.00 38.42  ? 254 ARG C N   1 
ATOM   5963  C  CA  . ARG C 1 254 ? 50.785  104.582 19.726  1.00 39.16  ? 254 ARG C CA  1 
ATOM   5964  C  C   . ARG C 1 254 ? 50.077  105.204 20.921  1.00 40.39  ? 254 ARG C C   1 
ATOM   5965  O  O   . ARG C 1 254 ? 50.051  104.617 22.010  1.00 41.71  ? 254 ARG C O   1 
ATOM   5966  C  CB  . ARG C 1 254 ? 50.166  103.236 19.387  1.00 42.34  ? 254 ARG C CB  1 
ATOM   5967  C  CG  . ARG C 1 254 ? 50.729  102.577 18.153  1.00 42.70  ? 254 ARG C CG  1 
ATOM   5968  C  CD  . ARG C 1 254 ? 49.879  101.383 17.855  1.00 42.18  ? 254 ARG C CD  1 
ATOM   5969  N  NE  . ARG C 1 254 ? 50.622  100.247 17.336  1.00 46.67  ? 254 ARG C NE  1 
ATOM   5970  C  CZ  . ARG C 1 254 ? 50.117  99.026  17.248  1.00 56.02  ? 254 ARG C CZ  1 
ATOM   5971  N  NH1 . ARG C 1 254 ? 48.901  98.750  17.701  1.00 57.52  ? 254 ARG C NH1 1 
ATOM   5972  N  NH2 . ARG C 1 254 ? 50.846  98.057  16.696  1.00 62.71  ? 254 ARG C NH2 1 
ATOM   5973  N  N   . LEU C 1 255 ? 49.501  106.383 20.723  1.00 39.73  ? 255 LEU C N   1 
ATOM   5974  C  CA  . LEU C 1 255 ? 48.775  107.085 21.771  1.00 36.45  ? 255 LEU C CA  1 
ATOM   5975  C  C   . LEU C 1 255 ? 47.283  107.065 21.460  1.00 39.02  ? 255 LEU C C   1 
ATOM   5976  O  O   . LEU C 1 255 ? 46.882  107.133 20.294  1.00 35.65  ? 255 LEU C O   1 
ATOM   5977  C  CB  . LEU C 1 255 ? 49.281  108.525 21.916  1.00 39.79  ? 255 LEU C CB  1 
ATOM   5978  C  CG  . LEU C 1 255 ? 50.816  108.673 21.997  1.00 43.93  ? 255 LEU C CG  1 
ATOM   5979  C  CD1 . LEU C 1 255 ? 51.233  110.134 22.164  1.00 38.62  ? 255 LEU C CD1 1 
ATOM   5980  C  CD2 . LEU C 1 255 ? 51.458  107.806 23.093  1.00 40.75  ? 255 LEU C CD2 1 
ATOM   5981  N  N   . ALA C 1 256 ? 46.468  106.965 22.511  1.00 39.30  ? 256 ALA C N   1 
ATOM   5982  C  CA  . ALA C 1 256 ? 45.024  106.787 22.382  1.00 38.45  ? 256 ALA C CA  1 
ATOM   5983  C  C   . ALA C 1 256 ? 44.418  107.739 21.367  1.00 40.17  ? 256 ALA C C   1 
ATOM   5984  O  O   . ALA C 1 256 ? 44.694  108.926 21.425  1.00 43.96  ? 256 ALA C O   1 
ATOM   5985  C  CB  . ALA C 1 256 ? 44.352  106.973 23.733  1.00 33.94  ? 256 ALA C CB  1 
ATOM   5986  N  N   . ALA D 1 3   ? 99.459  114.655 75.268  1.00 37.27  ? 3   ALA D N   1 
ATOM   5987  C  CA  . ALA D 1 3   ? 98.029  114.945 75.160  1.00 40.67  ? 3   ALA D CA  1 
ATOM   5988  C  C   . ALA D 1 3   ? 97.611  114.983 73.701  1.00 42.96  ? 3   ALA D C   1 
ATOM   5989  O  O   . ALA D 1 3   ? 98.363  115.482 72.862  1.00 41.72  ? 3   ALA D O   1 
ATOM   5990  C  CB  . ALA D 1 3   ? 97.692  116.252 75.830  1.00 42.57  ? 3   ALA D CB  1 
ATOM   5991  N  N   . PRO D 1 4   ? 96.421  114.466 73.388  1.00 39.40  ? 4   PRO D N   1 
ATOM   5992  C  CA  . PRO D 1 4   ? 96.031  114.342 71.981  1.00 41.24  ? 4   PRO D CA  1 
ATOM   5993  C  C   . PRO D 1 4   ? 95.778  115.689 71.324  1.00 39.51  ? 4   PRO D C   1 
ATOM   5994  O  O   . PRO D 1 4   ? 95.313  116.637 71.958  1.00 41.49  ? 4   PRO D O   1 
ATOM   5995  C  CB  . PRO D 1 4   ? 94.750  113.500 72.042  1.00 42.04  ? 4   PRO D CB  1 
ATOM   5996  C  CG  . PRO D 1 4   ? 94.832  112.783 73.363  1.00 41.40  ? 4   PRO D CG  1 
ATOM   5997  C  CD  . PRO D 1 4   ? 95.438  113.812 74.271  1.00 43.20  ? 4   PRO D CD  1 
ATOM   5998  N  N   . ARG D 1 5   ? 96.097  115.755 70.029  1.00 38.26  ? 5   ARG D N   1 
ATOM   5999  C  CA  . ARG D 1 5   ? 95.863  116.926 69.192  1.00 42.95  ? 5   ARG D CA  1 
ATOM   6000  C  C   . ARG D 1 5   ? 95.279  116.490 67.847  1.00 40.83  ? 5   ARG D C   1 
ATOM   6001  O  O   . ARG D 1 5   ? 95.486  115.357 67.393  1.00 38.91  ? 5   ARG D O   1 
ATOM   6002  C  CB  . ARG D 1 5   ? 97.175  117.736 68.951  1.00 44.97  ? 5   ARG D CB  1 
ATOM   6003  C  CG  . ARG D 1 5   ? 97.745  118.466 70.180  1.00 45.49  ? 5   ARG D CG  1 
ATOM   6004  C  CD  . ARG D 1 5   ? 98.581  119.734 69.818  1.00 60.79  ? 5   ARG D CD  1 
ATOM   6005  N  NE  . ARG D 1 5   ? 97.954  120.587 68.804  1.00 62.30  ? 5   ARG D NE  1 
ATOM   6006  C  CZ  . ARG D 1 5   ? 98.440  121.745 68.365  1.00 56.32  ? 5   ARG D CZ  1 
ATOM   6007  N  NH1 . ARG D 1 5   ? 99.527  122.288 68.898  1.00 60.26  ? 5   ARG D NH1 1 
ATOM   6008  N  NH2 . ARG D 1 5   ? 97.809  122.382 67.379  1.00 48.71  ? 5   ARG D NH2 1 
ATOM   6009  N  N   . LEU D 1 6   ? 94.563  117.411 67.201  1.00 37.91  ? 6   LEU D N   1 
ATOM   6010  C  CA  . LEU D 1 6   ? 94.002  117.210 65.871  1.00 36.06  ? 6   LEU D CA  1 
ATOM   6011  C  C   . LEU D 1 6   ? 94.687  118.136 64.867  1.00 39.68  ? 6   LEU D C   1 
ATOM   6012  O  O   . LEU D 1 6   ? 94.707  119.356 65.059  1.00 35.47  ? 6   LEU D O   1 
ATOM   6013  C  CB  . LEU D 1 6   ? 92.489  117.472 65.878  1.00 34.35  ? 6   LEU D CB  1 
ATOM   6014  C  CG  . LEU D 1 6   ? 91.809  117.641 64.507  1.00 37.28  ? 6   LEU D CG  1 
ATOM   6015  C  CD1 . LEU D 1 6   ? 91.950  116.359 63.673  1.00 34.65  ? 6   LEU D CD1 1 
ATOM   6016  C  CD2 . LEU D 1 6   ? 90.329  118.062 64.630  1.00 30.44  ? 6   LEU D CD2 1 
ATOM   6017  N  N   . TYR D 1 7   ? 95.212  117.564 63.783  1.00 36.26  ? 7   TYR D N   1 
ATOM   6018  C  CA  . TYR D 1 7   ? 95.826  118.340 62.707  1.00 40.53  ? 7   TYR D CA  1 
ATOM   6019  C  C   . TYR D 1 7   ? 95.018  118.148 61.431  1.00 39.78  ? 7   TYR D C   1 
ATOM   6020  O  O   . TYR D 1 7   ? 94.846  117.013 60.970  1.00 37.38  ? 7   TYR D O   1 
ATOM   6021  C  CB  . TYR D 1 7   ? 97.286  117.925 62.469  1.00 39.80  ? 7   TYR D CB  1 
ATOM   6022  C  CG  . TYR D 1 7   ? 98.239  118.294 63.588  1.00 41.90  ? 7   TYR D CG  1 
ATOM   6023  C  CD1 . TYR D 1 7   ? 98.320  117.521 64.737  1.00 41.42  ? 7   TYR D CD1 1 
ATOM   6024  C  CD2 . TYR D 1 7   ? 99.046  119.429 63.501  1.00 44.15  ? 7   TYR D CD2 1 
ATOM   6025  C  CE1 . TYR D 1 7   ? 99.187  117.848 65.761  1.00 45.12  ? 7   TYR D CE1 1 
ATOM   6026  C  CE2 . TYR D 1 7   ? 99.914  119.770 64.523  1.00 41.19  ? 7   TYR D CE2 1 
ATOM   6027  C  CZ  . TYR D 1 7   ? 99.980  118.974 65.645  1.00 46.45  ? 7   TYR D CZ  1 
ATOM   6028  O  OH  . TYR D 1 7   ? 100.828 119.300 66.667  1.00 53.66  ? 7   TYR D OH  1 
ATOM   6029  N  N   . MET D 1 8   ? 94.551  119.256 60.850  1.00 38.16  ? 8   MET D N   1 
ATOM   6030  C  CA  . MET D 1 8   ? 93.776  119.245 59.613  1.00 38.42  ? 8   MET D CA  1 
ATOM   6031  C  C   . MET D 1 8   ? 94.696  119.637 58.462  1.00 37.51  ? 8   MET D C   1 
ATOM   6032  O  O   . MET D 1 8   ? 95.115  120.793 58.359  1.00 45.33  ? 8   MET D O   1 
ATOM   6033  C  CB  . MET D 1 8   ? 92.577  120.193 59.718  1.00 38.48  ? 8   MET D CB  1 
ATOM   6034  C  CG  . MET D 1 8   ? 91.878  120.127 61.082  1.00 40.17  ? 8   MET D CG  1 
ATOM   6035  S  SD  . MET D 1 8   ? 90.057  120.109 61.056  1.00 46.66  ? 8   MET D SD  1 
ATOM   6036  C  CE  . MET D 1 8   ? 89.744  121.703 60.319  1.00 42.40  ? 8   MET D CE  1 
ATOM   6037  N  N   . PHE D 1 9   ? 95.019  118.671 57.610  1.00 40.45  ? 9   PHE D N   1 
ATOM   6038  C  CA  . PHE D 1 9   ? 95.829  118.859 56.420  1.00 36.77  ? 9   PHE D CA  1 
ATOM   6039  C  C   . PHE D 1 9   ? 94.923  118.970 55.203  1.00 39.35  ? 9   PHE D C   1 
ATOM   6040  O  O   . PHE D 1 9   ? 93.690  118.962 55.309  1.00 38.81  ? 9   PHE D O   1 
ATOM   6041  C  CB  . PHE D 1 9   ? 96.799  117.690 56.233  1.00 41.73  ? 9   PHE D CB  1 
ATOM   6042  C  CG  . PHE D 1 9   ? 97.949  117.676 57.196  1.00 44.85  ? 9   PHE D CG  1 
ATOM   6043  C  CD1 . PHE D 1 9   ? 97.786  117.178 58.481  1.00 41.98  ? 9   PHE D CD1 1 
ATOM   6044  C  CD2 . PHE D 1 9   ? 99.208  118.124 56.802  1.00 42.09  ? 9   PHE D CD2 1 
ATOM   6045  C  CE1 . PHE D 1 9   ? 98.848  117.152 59.373  1.00 42.49  ? 9   PHE D CE1 1 
ATOM   6046  C  CE2 . PHE D 1 9   ? 100.275 118.096 57.678  1.00 41.60  ? 9   PHE D CE2 1 
ATOM   6047  C  CZ  . PHE D 1 9   ? 100.096 117.613 58.972  1.00 45.39  ? 9   PHE D CZ  1 
ATOM   6048  N  N   . GLN D 1 10  ? 95.533  119.025 54.023  1.00 40.28  ? 10  GLN D N   1 
ATOM   6049  C  CA  . GLN D 1 10  ? 94.766  118.945 52.792  1.00 40.16  ? 10  GLN D CA  1 
ATOM   6050  C  C   . GLN D 1 10  ? 95.697  118.531 51.665  1.00 43.61  ? 10  GLN D C   1 
ATOM   6051  O  O   . GLN D 1 10  ? 96.874  118.908 51.660  1.00 44.44  ? 10  GLN D O   1 
ATOM   6052  C  CB  . GLN D 1 10  ? 94.061  120.276 52.504  1.00 41.76  ? 10  GLN D CB  1 
ATOM   6053  C  CG  . GLN D 1 10  ? 94.700  121.172 51.466  1.00 42.42  ? 10  GLN D CG  1 
ATOM   6054  C  CD  . GLN D 1 10  ? 93.915  122.463 51.301  1.00 37.43  ? 10  GLN D CD  1 
ATOM   6055  O  OE1 . GLN D 1 10  ? 93.806  123.256 52.233  1.00 34.08  ? 10  GLN D OE1 1 
ATOM   6056  N  NE2 . GLN D 1 10  ? 93.352  122.667 50.121  1.00 38.43  ? 10  GLN D NE2 1 
ATOM   6057  N  N   . THR D 1 11  ? 95.181  117.712 50.744  1.00 41.26  ? 11  THR D N   1 
ATOM   6058  C  CA  . THR D 1 11  ? 95.922  117.360 49.530  1.00 44.26  ? 11  THR D CA  1 
ATOM   6059  C  C   . THR D 1 11  ? 95.402  118.185 48.353  1.00 45.58  ? 11  THR D C   1 
ATOM   6060  O  O   . THR D 1 11  ? 94.793  117.687 47.406  1.00 45.80  ? 11  THR D O   1 
ATOM   6061  C  CB  . THR D 1 11  ? 95.848  115.853 49.258  1.00 41.94  ? 11  THR D CB  1 
ATOM   6062  O  OG1 . THR D 1 11  ? 94.484  115.438 49.062  1.00 41.76  ? 11  THR D OG1 1 
ATOM   6063  C  CG2 . THR D 1 11  ? 96.454  115.099 50.422  1.00 40.29  ? 11  THR D CG2 1 
ATOM   6064  N  N   . GLY D 1 12  ? 95.654  119.484 48.453  1.00 46.66  ? 12  GLY D N   1 
ATOM   6065  C  CA  . GLY D 1 12  ? 95.363  120.378 47.343  1.00 44.45  ? 12  GLY D CA  1 
ATOM   6066  C  C   . GLY D 1 12  ? 93.872  120.630 47.197  1.00 45.61  ? 12  GLY D C   1 
ATOM   6067  O  O   . GLY D 1 12  ? 93.149  120.897 48.171  1.00 44.83  ? 12  GLY D O   1 
ATOM   6068  N  N   . THR D 1 13  ? 93.408  120.575 45.951  1.00 40.19  ? 13  THR D N   1 
ATOM   6069  C  CA  . THR D 1 13  ? 92.018  120.854 45.627  1.00 46.01  ? 13  THR D CA  1 
ATOM   6070  C  C   . THR D 1 13  ? 91.561  119.917 44.525  1.00 47.62  ? 13  THR D C   1 
ATOM   6071  O  O   . THR D 1 13  ? 92.364  119.242 43.870  1.00 49.70  ? 13  THR D O   1 
ATOM   6072  C  CB  . THR D 1 13  ? 91.805  122.308 45.169  1.00 45.14  ? 13  THR D CB  1 
ATOM   6073  O  OG1 . THR D 1 13  ? 92.742  122.631 44.133  1.00 48.51  ? 13  THR D OG1 1 
ATOM   6074  C  CG2 . THR D 1 13  ? 91.955  123.288 46.321  1.00 44.87  ? 13  THR D CG2 1 
ATOM   6075  N  N   . LEU D 1 14  ? 90.249  119.891 44.324  1.00 45.17  ? 14  LEU D N   1 
ATOM   6076  C  CA  . LEU D 1 14  ? 89.647  119.280 43.153  1.00 44.75  ? 14  LEU D CA  1 
ATOM   6077  C  C   . LEU D 1 14  ? 88.957  120.366 42.352  1.00 44.69  ? 14  LEU D C   1 
ATOM   6078  O  O   . LEU D 1 14  ? 88.310  121.251 42.923  1.00 45.19  ? 14  LEU D O   1 
ATOM   6079  C  CB  . LEU D 1 14  ? 88.632  118.196 43.526  1.00 48.30  ? 14  LEU D CB  1 
ATOM   6080  C  CG  . LEU D 1 14  ? 89.086  117.014 44.382  1.00 45.83  ? 14  LEU D CG  1 
ATOM   6081  C  CD1 . LEU D 1 14  ? 87.928  116.058 44.602  1.00 42.65  ? 14  LEU D CD1 1 
ATOM   6082  C  CD2 . LEU D 1 14  ? 90.255  116.301 43.735  1.00 43.42  ? 14  LEU D CD2 1 
ATOM   6083  N  N   . LYS D 1 15  ? 89.108  120.311 41.034  1.00 43.64  ? 15  LYS D N   1 
ATOM   6084  C  CA  . LYS D 1 15  ? 88.380  121.196 40.138  1.00 46.96  ? 15  LYS D CA  1 
ATOM   6085  C  C   . LYS D 1 15  ? 87.268  120.394 39.478  1.00 49.58  ? 15  LYS D C   1 
ATOM   6086  O  O   . LYS D 1 15  ? 87.526  119.335 38.889  1.00 47.52  ? 15  LYS D O   1 
ATOM   6087  C  CB  . LYS D 1 15  ? 89.305  121.813 39.082  1.00 53.57  ? 15  LYS D CB  1 
ATOM   6088  C  CG  . LYS D 1 15  ? 90.258  122.894 39.605  1.00 54.19  ? 15  LYS D CG  1 
ATOM   6089  C  CD  . LYS D 1 15  ? 90.959  123.628 38.454  1.00 53.59  ? 15  LYS D CD  1 
ATOM   6090  C  CE  . LYS D 1 15  ? 91.192  125.097 38.796  1.00 59.58  ? 15  LYS D CE  1 
ATOM   6091  N  NZ  . LYS D 1 15  ? 90.635  126.016 37.762  1.00 61.95  ? 15  LYS D NZ  1 
ATOM   6092  N  N   . CYS D 1 16  ? 86.041  120.885 39.591  1.00 44.15  ? 16  CYS D N   1 
ATOM   6093  C  CA  . CYS D 1 16  ? 84.895  120.196 39.010  1.00 49.45  ? 16  CYS D CA  1 
ATOM   6094  C  C   . CYS D 1 16  ? 83.830  121.239 38.695  1.00 52.52  ? 16  CYS D C   1 
ATOM   6095  O  O   . CYS D 1 16  ? 84.137  122.419 38.493  1.00 53.51  ? 16  CYS D O   1 
ATOM   6096  C  CB  . CYS D 1 16  ? 84.387  119.102 39.964  1.00 47.75  ? 16  CYS D CB  1 
ATOM   6097  S  SG  . CYS D 1 16  ? 83.932  119.707 41.610  1.00 48.89  ? 16  CYS D SG  1 
ATOM   6098  N  N   . ARG D 1 17  ? 82.576  120.805 38.660  1.00 51.15  ? 17  ARG D N   1 
ATOM   6099  C  CA  . ARG D 1 17  ? 81.435  121.682 38.462  1.00 51.58  ? 17  ARG D CA  1 
ATOM   6100  C  C   . ARG D 1 17  ? 80.630  121.784 39.752  1.00 51.41  ? 17  ARG D C   1 
ATOM   6101  O  O   . ARG D 1 17  ? 80.713  120.925 40.635  1.00 52.79  ? 17  ARG D O   1 
ATOM   6102  C  CB  . ARG D 1 17  ? 80.554  121.169 37.322  1.00 56.86  ? 17  ARG D CB  1 
ATOM   6103  C  CG  . ARG D 1 17  ? 81.256  121.132 35.981  1.00 59.95  ? 17  ARG D CG  1 
ATOM   6104  C  CD  . ARG D 1 17  ? 80.358  120.525 34.904  1.00 69.59  ? 17  ARG D CD  1 
ATOM   6105  N  NE  . ARG D 1 17  ? 81.022  120.459 33.606  1.00 77.62  ? 17  ARG D NE  1 
ATOM   6106  C  CZ  . ARG D 1 17  ? 81.146  121.488 32.777  1.00 76.60  ? 17  ARG D CZ  1 
ATOM   6107  N  NH1 . ARG D 1 17  ? 80.629  122.673 33.063  1.00 73.23  ? 17  ARG D NH1 1 
ATOM   6108  N  NH2 . ARG D 1 17  ? 81.805  121.324 31.633  1.00 74.04  ? 17  ARG D NH2 1 
ATOM   6109  N  N   . VAL D 1 18  ? 79.850  122.860 39.858  1.00 53.95  ? 18  VAL D N   1 
ATOM   6110  C  CA  . VAL D 1 18  ? 79.082  123.088 41.080  1.00 50.76  ? 18  VAL D CA  1 
ATOM   6111  C  C   . VAL D 1 18  ? 78.113  121.933 41.316  1.00 51.58  ? 18  VAL D C   1 
ATOM   6112  O  O   . VAL D 1 18  ? 77.903  121.503 42.458  1.00 48.51  ? 18  VAL D O   1 
ATOM   6113  C  CB  . VAL D 1 18  ? 78.363  124.452 41.010  1.00 54.14  ? 18  VAL D CB  1 
ATOM   6114  C  CG1 . VAL D 1 18  ? 77.527  124.710 42.263  1.00 46.80  ? 18  VAL D CG1 1 
ATOM   6115  C  CG2 . VAL D 1 18  ? 79.380  125.584 40.812  1.00 55.10  ? 18  VAL D CG2 1 
ATOM   6116  N  N   . CYS D 1 19  ? 77.558  121.376 40.230  1.00 50.26  ? 19  CYS D N   1 
ATOM   6117  C  CA  . CYS D 1 19  ? 76.549  120.324 40.335  1.00 48.42  ? 19  CYS D CA  1 
ATOM   6118  C  C   . CYS D 1 19  ? 77.101  119.043 40.957  1.00 47.85  ? 19  CYS D C   1 
ATOM   6119  O  O   . CYS D 1 19  ? 76.338  118.270 41.555  1.00 46.45  ? 19  CYS D O   1 
ATOM   6120  C  CB  . CYS D 1 19  ? 75.961  120.026 38.955  1.00 48.14  ? 19  CYS D CB  1 
ATOM   6121  S  SG  . CYS D 1 19  ? 77.149  119.334 37.744  1.00 49.08  ? 19  CYS D SG  1 
ATOM   6122  N  N   . ASN D 1 20  ? 78.404  118.782 40.816  1.00 46.49  ? 20  ASN D N   1 
ATOM   6123  C  CA  . ASN D 1 20  ? 78.982  117.618 41.478  1.00 47.19  ? 20  ASN D CA  1 
ATOM   6124  C  C   . ASN D 1 20  ? 78.942  117.737 42.994  1.00 47.33  ? 20  ASN D C   1 
ATOM   6125  O  O   . ASN D 1 20  ? 78.945  116.713 43.683  1.00 44.36  ? 20  ASN D O   1 
ATOM   6126  C  CB  . ASN D 1 20  ? 80.425  117.400 41.034  1.00 47.78  ? 20  ASN D CB  1 
ATOM   6127  C  CG  . ASN D 1 20  ? 80.558  117.246 39.543  1.00 51.59  ? 20  ASN D CG  1 
ATOM   6128  O  OD1 . ASN D 1 20  ? 81.156  118.089 38.878  1.00 54.97  ? 20  ASN D OD1 1 
ATOM   6129  N  ND2 . ASN D 1 20  ? 80.014  116.162 39.006  1.00 51.32  ? 20  ASN D ND2 1 
ATOM   6130  N  N   . ILE D 1 21  ? 78.922  118.951 43.529  1.00 45.31  ? 21  ILE D N   1 
ATOM   6131  C  CA  . ILE D 1 21  ? 78.890  119.160 44.966  1.00 47.34  ? 21  ILE D CA  1 
ATOM   6132  C  C   . ILE D 1 21  ? 77.463  119.380 45.453  1.00 44.72  ? 21  ILE D C   1 
ATOM   6133  O  O   . ILE D 1 21  ? 77.013  118.732 46.398  1.00 45.91  ? 21  ILE D O   1 
ATOM   6134  C  CB  . ILE D 1 21  ? 79.817  120.332 45.369  1.00 46.12  ? 21  ILE D CB  1 
ATOM   6135  C  CG1 . ILE D 1 21  ? 81.294  119.910 45.428  1.00 46.04  ? 21  ILE D CG1 1 
ATOM   6136  C  CG2 . ILE D 1 21  ? 79.422  120.870 46.734  1.00 46.23  ? 21  ILE D CG2 1 
ATOM   6137  C  CD1 . ILE D 1 21  ? 81.822  119.122 44.236  1.00 50.71  ? 21  ILE D CD1 1 
ATOM   6138  N  N   . LYS D 1 22  ? 76.728  120.276 44.802  1.00 44.28  ? 22  LYS D N   1 
ATOM   6139  C  CA  . LYS D 1 22  ? 75.339  120.562 45.139  1.00 45.29  ? 22  LYS D CA  1 
ATOM   6140  C  C   . LYS D 1 22  ? 74.499  120.098 43.955  1.00 47.14  ? 22  LYS D C   1 
ATOM   6141  O  O   . LYS D 1 22  ? 74.577  120.683 42.870  1.00 44.58  ? 22  LYS D O   1 
ATOM   6142  C  CB  . LYS D 1 22  ? 75.150  122.047 45.435  1.00 44.73  ? 22  LYS D CB  1 
ATOM   6143  C  CG  . LYS D 1 22  ? 76.311  122.644 46.221  1.00 46.26  ? 22  LYS D CG  1 
ATOM   6144  C  CD  . LYS D 1 22  ? 76.091  124.106 46.592  1.00 51.51  ? 22  LYS D CD  1 
ATOM   6145  C  CE  . LYS D 1 22  ? 76.557  124.395 48.023  1.00 45.38  ? 22  LYS D CE  1 
ATOM   6146  N  NZ  . LYS D 1 22  ? 76.925  125.827 48.223  1.00 48.39  ? 22  LYS D NZ  1 
ATOM   6147  N  N   . MET D 1 23  ? 73.715  119.038 44.166  1.00 42.43  ? 23  MET D N   1 
ATOM   6148  C  CA  . MET D 1 23  ? 73.048  118.347 43.067  1.00 44.84  ? 23  MET D CA  1 
ATOM   6149  C  C   . MET D 1 23  ? 72.135  119.299 42.297  1.00 45.49  ? 23  MET D C   1 
ATOM   6150  O  O   . MET D 1 23  ? 71.365  120.059 42.893  1.00 44.85  ? 23  MET D O   1 
ATOM   6151  C  CB  . MET D 1 23  ? 72.245  117.154 43.610  1.00 43.53  ? 23  MET D CB  1 
ATOM   6152  C  CG  . MET D 1 23  ? 71.633  116.262 42.519  1.00 47.29  ? 23  MET D CG  1 
ATOM   6153  S  SD  . MET D 1 23  ? 70.466  114.989 43.071  1.00 48.24  ? 23  MET D SD  1 
ATOM   6154  C  CE  . MET D 1 23  ? 69.080  115.977 43.640  1.00 43.31  ? 23  MET D CE  1 
ATOM   6155  N  N   . ASN D 1 24  ? 72.252  119.275 40.966  1.00 46.44  ? 24  ASN D N   1 
ATOM   6156  C  CA  . ASN D 1 24  ? 71.378  120.009 40.050  1.00 49.11  ? 24  ASN D CA  1 
ATOM   6157  C  C   . ASN D 1 24  ? 71.483  121.529 40.215  1.00 53.96  ? 24  ASN D C   1 
ATOM   6158  O  O   . ASN D 1 24  ? 70.556  122.262 39.838  1.00 50.03  ? 24  ASN D O   1 
ATOM   6159  C  CB  . ASN D 1 24  ? 69.912  119.567 40.199  1.00 46.12  ? 24  ASN D CB  1 
ATOM   6160  C  CG  . ASN D 1 24  ? 69.702  118.085 39.873  1.00 51.53  ? 24  ASN D CG  1 
ATOM   6161  O  OD1 . ASN D 1 24  ? 70.464  117.492 39.098  1.00 49.09  ? 24  ASN D OD1 1 
ATOM   6162  N  ND2 . ASN D 1 24  ? 68.664  117.483 40.467  1.00 41.59  ? 24  ASN D ND2 1 
ATOM   6163  N  N   . ALA D 1 25  ? 72.604  122.030 40.744  1.00 49.13  ? 25  ALA D N   1 
ATOM   6164  C  CA  . ALA D 1 25  ? 72.738  123.444 41.076  1.00 54.78  ? 25  ALA D CA  1 
ATOM   6165  C  C   . ALA D 1 25  ? 73.544  124.235 40.046  1.00 54.73  ? 25  ALA D C   1 
ATOM   6166  O  O   . ALA D 1 25  ? 74.029  125.327 40.361  1.00 62.57  ? 25  ALA D O   1 
ATOM   6167  C  CB  . ALA D 1 25  ? 73.366  123.607 42.461  1.00 55.51  ? 25  ALA D CB  1 
ATOM   6168  N  N   . GLY D 1 26  ? 73.685  123.727 38.833  1.00 51.88  ? 26  GLY D N   1 
ATOM   6169  C  CA  . GLY D 1 26  ? 74.341  124.484 37.789  1.00 57.94  ? 26  GLY D CA  1 
ATOM   6170  C  C   . GLY D 1 26  ? 75.650  123.844 37.354  1.00 58.84  ? 26  GLY D C   1 
ATOM   6171  O  O   . GLY D 1 26  ? 76.241  123.020 38.054  1.00 56.80  ? 26  GLY D O   1 
ATOM   6172  N  N   . LEU D 1 27  ? 76.114  124.262 36.175  1.00 57.79  ? 27  LEU D N   1 
ATOM   6173  C  CA  . LEU D 1 27  ? 77.282  123.685 35.527  1.00 56.40  ? 27  LEU D CA  1 
ATOM   6174  C  C   . LEU D 1 27  ? 78.537  124.542 35.676  1.00 58.18  ? 27  LEU D C   1 
ATOM   6175  O  O   . LEU D 1 27  ? 79.544  124.263 35.015  1.00 57.68  ? 27  LEU D O   1 
ATOM   6176  C  CB  . LEU D 1 27  ? 76.986  123.455 34.045  1.00 59.66  ? 27  LEU D CB  1 
ATOM   6177  C  CG  . LEU D 1 27  ? 75.923  122.414 33.700  1.00 59.16  ? 27  LEU D CG  1 
ATOM   6178  C  CD1 . LEU D 1 27  ? 76.127  121.933 32.281  1.00 58.96  ? 27  LEU D CD1 1 
ATOM   6179  C  CD2 . LEU D 1 27  ? 75.961  121.243 34.685  1.00 59.12  ? 27  LEU D CD2 1 
ATOM   6180  N  N   . ASP D 1 28  ? 78.502  125.573 36.519  1.00 58.58  ? 28  ASP D N   1 
ATOM   6181  C  CA  . ASP D 1 28  ? 79.646  126.462 36.692  1.00 57.16  ? 28  ASP D CA  1 
ATOM   6182  C  C   . ASP D 1 28  ? 80.865  125.700 37.207  1.00 59.73  ? 28  ASP D C   1 
ATOM   6183  O  O   . ASP D 1 28  ? 80.755  124.642 37.831  1.00 57.46  ? 28  ASP D O   1 
ATOM   6184  C  CB  . ASP D 1 28  ? 79.305  127.588 37.667  1.00 59.11  ? 28  ASP D CB  1 
ATOM   6185  C  CG  . ASP D 1 28  ? 78.476  128.686 37.029  1.00 66.24  ? 28  ASP D CG  1 
ATOM   6186  O  OD1 . ASP D 1 28  ? 78.266  128.642 35.798  1.00 63.05  ? 28  ASP D OD1 1 
ATOM   6187  O  OD2 . ASP D 1 28  ? 78.026  129.593 37.763  1.00 69.66  ? 28  ASP D OD2 1 
ATOM   6188  N  N   . ASP D 1 29  ? 82.045  126.260 36.938  1.00 63.32  ? 29  ASP D N   1 
ATOM   6189  C  CA  . ASP D 1 29  ? 83.282  125.721 37.486  1.00 57.15  ? 29  ASP D CA  1 
ATOM   6190  C  C   . ASP D 1 29  ? 83.325  125.916 38.999  1.00 55.37  ? 29  ASP D C   1 
ATOM   6191  O  O   . ASP D 1 29  ? 82.794  126.892 39.541  1.00 53.60  ? 29  ASP D O   1 
ATOM   6192  C  CB  . ASP D 1 29  ? 84.497  126.383 36.832  1.00 56.00  ? 29  ASP D CB  1 
ATOM   6193  C  CG  . ASP D 1 29  ? 84.750  125.872 35.426  1.00 62.61  ? 29  ASP D CG  1 
ATOM   6194  O  OD1 . ASP D 1 29  ? 84.140  124.851 35.042  1.00 61.02  ? 29  ASP D OD1 1 
ATOM   6195  O  OD2 . ASP D 1 29  ? 85.556  126.493 34.698  1.00 68.96  ? 29  ASP D OD2 1 
ATOM   6196  N  N   . TYR D 1 30  ? 83.976  124.971 39.677  1.00 50.94  ? 30  TYR D N   1 
ATOM   6197  C  CA  . TYR D 1 30  ? 83.961  124.890 41.130  1.00 46.86  ? 30  TYR D CA  1 
ATOM   6198  C  C   . TYR D 1 30  ? 85.236  124.199 41.593  1.00 46.39  ? 30  TYR D C   1 
ATOM   6199  O  O   . TYR D 1 30  ? 85.700  123.251 40.950  1.00 45.81  ? 30  TYR D O   1 
ATOM   6200  C  CB  . TYR D 1 30  ? 82.718  124.122 41.610  1.00 50.40  ? 30  TYR D CB  1 
ATOM   6201  C  CG  . TYR D 1 30  ? 82.311  124.346 43.054  1.00 47.20  ? 30  TYR D CG  1 
ATOM   6202  C  CD1 . TYR D 1 30  ? 81.968  125.610 43.517  1.00 46.55  ? 30  TYR D CD1 1 
ATOM   6203  C  CD2 . TYR D 1 30  ? 82.233  123.277 43.942  1.00 48.17  ? 30  TYR D CD2 1 
ATOM   6204  C  CE1 . TYR D 1 30  ? 81.582  125.809 44.835  1.00 49.73  ? 30  TYR D CE1 1 
ATOM   6205  C  CE2 . TYR D 1 30  ? 81.848  123.459 45.255  1.00 46.82  ? 30  TYR D CE2 1 
ATOM   6206  C  CZ  . TYR D 1 30  ? 81.523  124.727 45.703  1.00 51.51  ? 30  TYR D CZ  1 
ATOM   6207  O  OH  . TYR D 1 30  ? 81.136  124.907 47.014  1.00 45.42  ? 30  TYR D OH  1 
ATOM   6208  N  N   . GLU D 1 31  ? 85.790  124.674 42.712  1.00 47.89  ? 31  GLU D N   1 
ATOM   6209  C  CA  . GLU D 1 31  ? 87.008  124.131 43.302  1.00 43.24  ? 31  GLU D CA  1 
ATOM   6210  C  C   . GLU D 1 31  ? 86.788  123.880 44.790  1.00 43.41  ? 31  GLU D C   1 
ATOM   6211  O  O   . GLU D 1 31  ? 86.223  124.724 45.493  1.00 42.43  ? 31  GLU D O   1 
ATOM   6212  C  CB  . GLU D 1 31  ? 88.197  125.089 43.102  1.00 44.65  ? 31  GLU D CB  1 
ATOM   6213  C  CG  . GLU D 1 31  ? 89.562  124.462 43.368  1.00 46.79  ? 31  GLU D CG  1 
ATOM   6214  C  CD  . GLU D 1 31  ? 90.700  125.212 42.685  1.00 50.59  ? 31  GLU D CD  1 
ATOM   6215  O  OE1 . GLU D 1 31  ? 90.431  126.249 42.042  1.00 48.08  ? 31  GLU D OE1 1 
ATOM   6216  O  OE2 . GLU D 1 31  ? 91.866  124.776 42.798  1.00 46.13  ? 31  GLU D OE2 1 
ATOM   6217  N  N   . ILE D 1 32  ? 87.234  122.720 45.270  1.00 43.16  ? 32  ILE D N   1 
ATOM   6218  C  CA  . ILE D 1 32  ? 87.018  122.328 46.665  1.00 42.21  ? 32  ILE D CA  1 
ATOM   6219  C  C   . ILE D 1 32  ? 88.334  121.880 47.288  1.00 42.22  ? 32  ILE D C   1 
ATOM   6220  O  O   . ILE D 1 32  ? 89.164  121.270 46.605  1.00 38.63  ? 32  ILE D O   1 
ATOM   6221  C  CB  . ILE D 1 32  ? 85.963  121.211 46.779  1.00 42.64  ? 32  ILE D CB  1 
ATOM   6222  C  CG1 . ILE D 1 32  ? 86.266  120.081 45.787  1.00 42.03  ? 32  ILE D CG1 1 
ATOM   6223  C  CG2 . ILE D 1 32  ? 84.544  121.762 46.578  1.00 39.20  ? 32  ILE D CG2 1 
ATOM   6224  C  CD1 . ILE D 1 32  ? 85.459  118.810 46.049  1.00 41.31  ? 32  ILE D CD1 1 
ATOM   6225  N  N   . PRO D 1 33  ? 88.560  122.132 48.573  1.00 37.56  ? 33  PRO D N   1 
ATOM   6226  C  CA  . PRO D 1 33  ? 89.714  121.526 49.235  1.00 38.16  ? 33  PRO D CA  1 
ATOM   6227  C  C   . PRO D 1 33  ? 89.459  120.049 49.486  1.00 38.30  ? 33  PRO D C   1 
ATOM   6228  O  O   . PRO D 1 33  ? 88.313  119.600 49.563  1.00 37.90  ? 33  PRO D O   1 
ATOM   6229  C  CB  . PRO D 1 33  ? 89.817  122.307 50.550  1.00 39.35  ? 33  PRO D CB  1 
ATOM   6230  C  CG  . PRO D 1 33  ? 88.391  122.676 50.858  1.00 36.99  ? 33  PRO D CG  1 
ATOM   6231  C  CD  . PRO D 1 33  ? 87.715  122.889 49.511  1.00 37.78  ? 33  PRO D CD  1 
ATOM   6232  N  N   . VAL D 1 34  ? 90.545  119.291 49.598  1.00 34.76  ? 34  VAL D N   1 
ATOM   6233  C  CA  . VAL D 1 34  ? 90.474  117.867 49.918  1.00 35.58  ? 34  VAL D CA  1 
ATOM   6234  C  C   . VAL D 1 34  ? 91.116  117.653 51.284  1.00 34.64  ? 34  VAL D C   1 
ATOM   6235  O  O   . VAL D 1 34  ? 92.333  117.429 51.370  1.00 35.82  ? 34  VAL D O   1 
ATOM   6236  C  CB  . VAL D 1 34  ? 91.173  117.013 48.853  1.00 36.98  ? 34  VAL D CB  1 
ATOM   6237  C  CG1 . VAL D 1 34  ? 91.077  115.517 49.213  1.00 34.67  ? 34  VAL D CG1 1 
ATOM   6238  C  CG2 . VAL D 1 34  ? 90.615  117.314 47.480  1.00 42.30  ? 34  VAL D CG2 1 
ATOM   6239  N  N   . PRO D 1 35  ? 90.354  117.729 52.367  1.00 35.69  ? 35  PRO D N   1 
ATOM   6240  C  CA  . PRO D 1 35  ? 90.947  117.575 53.698  1.00 33.58  ? 35  PRO D CA  1 
ATOM   6241  C  C   . PRO D 1 35  ? 91.363  116.144 53.996  1.00 32.86  ? 35  PRO D C   1 
ATOM   6242  O  O   . PRO D 1 35  ? 90.839  115.183 53.433  1.00 34.63  ? 35  PRO D O   1 
ATOM   6243  C  CB  . PRO D 1 35  ? 89.821  118.015 54.644  1.00 31.15  ? 35  PRO D CB  1 
ATOM   6244  C  CG  . PRO D 1 35  ? 88.825  118.722 53.794  1.00 34.70  ? 35  PRO D CG  1 
ATOM   6245  C  CD  . PRO D 1 35  ? 88.935  118.105 52.429  1.00 34.51  ? 35  PRO D CD  1 
ATOM   6246  N  N   . TRP D 1 36  ? 92.341  116.019 54.891  1.00 32.76  ? 36  TRP D N   1 
ATOM   6247  C  CA  . TRP D 1 36  ? 92.551  114.795 55.647  1.00 31.89  ? 36  TRP D CA  1 
ATOM   6248  C  C   . TRP D 1 36  ? 93.044  115.194 57.029  1.00 32.65  ? 36  TRP D C   1 
ATOM   6249  O  O   . TRP D 1 36  ? 93.303  116.366 57.295  1.00 34.91  ? 36  TRP D O   1 
ATOM   6250  C  CB  . TRP D 1 36  ? 93.506  113.827 54.942  1.00 35.15  ? 36  TRP D CB  1 
ATOM   6251  C  CG  . TRP D 1 36  ? 94.912  114.318 54.719  1.00 41.57  ? 36  TRP D CG  1 
ATOM   6252  C  CD1 . TRP D 1 36  ? 95.362  115.086 53.678  1.00 41.33  ? 36  TRP D CD1 1 
ATOM   6253  C  CD2 . TRP D 1 36  ? 96.059  114.028 55.527  1.00 40.60  ? 36  TRP D CD2 1 
ATOM   6254  N  NE1 . TRP D 1 36  ? 96.715  115.297 53.796  1.00 37.97  ? 36  TRP D NE1 1 
ATOM   6255  C  CE2 . TRP D 1 36  ? 97.169  114.661 54.921  1.00 40.21  ? 36  TRP D CE2 1 
ATOM   6256  C  CE3 . TRP D 1 36  ? 96.255  113.304 56.708  1.00 38.13  ? 36  TRP D CE3 1 
ATOM   6257  C  CZ2 . TRP D 1 36  ? 98.452  114.606 55.466  1.00 37.18  ? 36  TRP D CZ2 1 
ATOM   6258  C  CZ3 . TRP D 1 36  ? 97.536  113.240 57.241  1.00 39.38  ? 36  TRP D CZ3 1 
ATOM   6259  C  CH2 . TRP D 1 36  ? 98.616  113.892 56.617  1.00 40.32  ? 36  TRP D CH2 1 
ATOM   6260  N  N   . TYR D 1 37  ? 93.138  114.216 57.925  1.00 30.47  ? 37  TYR D N   1 
ATOM   6261  C  CA  . TYR D 1 37  ? 93.320  114.519 59.337  1.00 34.16  ? 37  TYR D CA  1 
ATOM   6262  C  C   . TYR D 1 37  ? 94.354  113.601 59.953  1.00 33.19  ? 37  TYR D C   1 
ATOM   6263  O  O   . TYR D 1 37  ? 94.480  112.428 59.589  1.00 33.21  ? 37  TYR D O   1 
ATOM   6264  C  CB  . TYR D 1 37  ? 92.005  114.409 60.128  1.00 29.99  ? 37  TYR D CB  1 
ATOM   6265  C  CG  . TYR D 1 37  ? 90.865  115.101 59.423  1.00 34.05  ? 37  TYR D CG  1 
ATOM   6266  C  CD1 . TYR D 1 37  ? 90.695  116.486 59.505  1.00 32.48  ? 37  TYR D CD1 1 
ATOM   6267  C  CD2 . TYR D 1 37  ? 89.979  114.375 58.633  1.00 33.86  ? 37  TYR D CD2 1 
ATOM   6268  C  CE1 . TYR D 1 37  ? 89.651  117.114 58.834  1.00 31.61  ? 37  TYR D CE1 1 
ATOM   6269  C  CE2 . TYR D 1 37  ? 88.942  114.993 57.963  1.00 32.80  ? 37  TYR D CE2 1 
ATOM   6270  C  CZ  . TYR D 1 37  ? 88.782  116.353 58.065  1.00 33.79  ? 37  TYR D CZ  1 
ATOM   6271  O  OH  . TYR D 1 37  ? 87.741  116.924 57.375  1.00 38.68  ? 37  TYR D OH  1 
ATOM   6272  N  N   . LEU D 1 38  ? 95.095  114.170 60.891  1.00 36.76  ? 38  LEU D N   1 
ATOM   6273  C  CA  . LEU D 1 38  ? 96.046  113.447 61.716  1.00 32.01  ? 38  LEU D CA  1 
ATOM   6274  C  C   . LEU D 1 38  ? 95.666  113.672 63.164  1.00 29.25  ? 38  LEU D C   1 
ATOM   6275  O  O   . LEU D 1 38  ? 95.420  114.810 63.564  1.00 34.51  ? 38  LEU D O   1 
ATOM   6276  C  CB  . LEU D 1 38  ? 97.468  113.943 61.468  1.00 33.90  ? 38  LEU D CB  1 
ATOM   6277  C  CG  . LEU D 1 38  ? 98.497  113.572 62.533  1.00 36.50  ? 38  LEU D CG  1 
ATOM   6278  C  CD1 . LEU D 1 38  ? 98.888  112.110 62.406  1.00 32.98  ? 38  LEU D CD1 1 
ATOM   6279  C  CD2 . LEU D 1 38  ? 99.720  114.487 62.453  1.00 35.09  ? 38  LEU D CD2 1 
ATOM   6280  N  N   . ILE D 1 39  ? 95.601  112.604 63.946  1.00 29.08  ? 39  ILE D N   1 
ATOM   6281  C  CA  . ILE D 1 39  ? 95.435  112.739 65.386  1.00 30.51  ? 39  ILE D CA  1 
ATOM   6282  C  C   . ILE D 1 39  ? 96.709  112.243 66.045  1.00 37.32  ? 39  ILE D C   1 
ATOM   6283  O  O   . ILE D 1 39  ? 97.134  111.100 65.815  1.00 33.12  ? 39  ILE D O   1 
ATOM   6284  C  CB  . ILE D 1 39  ? 94.209  111.986 65.922  1.00 32.31  ? 39  ILE D CB  1 
ATOM   6285  C  CG1 . ILE D 1 39  ? 92.916  112.567 65.337  1.00 31.48  ? 39  ILE D CG1 1 
ATOM   6286  C  CG2 . ILE D 1 39  ? 94.175  112.081 67.448  1.00 31.74  ? 39  ILE D CG2 1 
ATOM   6287  C  CD1 . ILE D 1 39  ? 92.470  111.914 64.050  1.00 32.17  ? 39  ILE D CD1 1 
ATOM   6288  N  N   . THR D 1 40  ? 97.329  113.124 66.834  1.00 37.31  ? 40  THR D N   1 
ATOM   6289  C  CA  . THR D 1 40  ? 98.431  112.757 67.711  1.00 35.76  ? 40  THR D CA  1 
ATOM   6290  C  C   . THR D 1 40  ? 97.865  112.205 69.003  1.00 36.87  ? 40  THR D C   1 
ATOM   6291  O  O   . THR D 1 40  ? 96.991  112.830 69.610  1.00 42.92  ? 40  THR D O   1 
ATOM   6292  C  CB  . THR D 1 40  ? 99.304  113.977 68.015  1.00 40.50  ? 40  THR D CB  1 
ATOM   6293  O  OG1 . THR D 1 40  ? 100.096 114.295 66.868  1.00 41.58  ? 40  THR D OG1 1 
ATOM   6294  C  CG2 . THR D 1 40  ? 100.223 113.680 69.198  1.00 42.23  ? 40  THR D CG2 1 
ATOM   6295  N  N   . HIS D 1 41  ? 98.360  111.043 69.438  1.00 35.75  ? 41  HIS D N   1 
ATOM   6296  C  CA  . HIS D 1 41  ? 97.774  110.451 70.638  1.00 39.76  ? 41  HIS D CA  1 
ATOM   6297  C  C   . HIS D 1 41  ? 98.882  109.713 71.364  1.00 34.37  ? 41  HIS D C   1 
ATOM   6298  O  O   . HIS D 1 41  ? 99.795  109.202 70.704  1.00 37.45  ? 41  HIS D O   1 
ATOM   6299  C  CB  . HIS D 1 41  ? 96.613  109.499 70.274  1.00 38.59  ? 41  HIS D CB  1 
ATOM   6300  C  CG  . HIS D 1 41  ? 95.741  109.096 71.428  1.00 34.85  ? 41  HIS D CG  1 
ATOM   6301  N  ND1 . HIS D 1 41  ? 96.068  108.070 72.292  1.00 34.96  ? 41  HIS D ND1 1 
ATOM   6302  C  CD2 . HIS D 1 41  ? 94.531  109.557 71.835  1.00 34.47  ? 41  HIS D CD2 1 
ATOM   6303  C  CE1 . HIS D 1 41  ? 95.104  107.924 73.186  1.00 37.66  ? 41  HIS D CE1 1 
ATOM   6304  N  NE2 . HIS D 1 41  ? 94.161  108.814 72.932  1.00 35.63  ? 41  HIS D NE2 1 
ATOM   6305  N  N   . PRO D 1 42  ? 98.863  109.679 72.696  1.00 35.44  ? 42  PRO D N   1 
ATOM   6306  C  CA  . PRO D 1 42  ? 99.901  108.928 73.417  1.00 38.84  ? 42  PRO D CA  1 
ATOM   6307  C  C   . PRO D 1 42  ? 100.004 107.483 72.970  1.00 40.67  ? 42  PRO D C   1 
ATOM   6308  O  O   . PRO D 1 42  ? 101.116 106.947 72.910  1.00 36.78  ? 42  PRO D O   1 
ATOM   6309  C  CB  . PRO D 1 42  ? 99.466  109.041 74.884  1.00 38.84  ? 42  PRO D CB  1 
ATOM   6310  C  CG  . PRO D 1 42  ? 98.619  110.250 74.952  1.00 37.30  ? 42  PRO D CG  1 
ATOM   6311  C  CD  . PRO D 1 42  ? 98.012  110.474 73.595  1.00 35.54  ? 42  PRO D CD  1 
ATOM   6312  N  N   . LYS D 1 43  ? 98.887  106.841 72.620  1.00 40.01  ? 43  LYS D N   1 
ATOM   6313  C  CA  . LYS D 1 43  ? 98.916  105.434 72.240  1.00 36.00  ? 43  LYS D CA  1 
ATOM   6314  C  C   . LYS D 1 43  ? 99.203  105.218 70.762  1.00 34.57  ? 43  LYS D C   1 
ATOM   6315  O  O   . LYS D 1 43  ? 99.262  104.067 70.322  1.00 35.55  ? 43  LYS D O   1 
ATOM   6316  C  CB  . LYS D 1 43  ? 97.602  104.747 72.611  1.00 38.15  ? 43  LYS D CB  1 
ATOM   6317  C  CG  . LYS D 1 43  ? 97.241  104.833 74.093  1.00 43.38  ? 43  LYS D CG  1 
ATOM   6318  C  CD  . LYS D 1 43  ? 96.553  103.545 74.555  1.00 48.73  ? 43  LYS D CD  1 
ATOM   6319  C  CE  . LYS D 1 43  ? 95.580  103.783 75.713  1.00 50.41  ? 43  LYS D CE  1 
ATOM   6320  N  NZ  . LYS D 1 43  ? 94.168  103.517 75.292  1.00 51.95  ? 43  LYS D NZ  1 
ATOM   6321  N  N   . GLY D 1 44  ? 99.393  106.268 69.989  1.00 33.23  ? 44  GLY D N   1 
ATOM   6322  C  CA  . GLY D 1 44  ? 99.771  106.090 68.601  1.00 37.21  ? 44  GLY D CA  1 
ATOM   6323  C  C   . GLY D 1 44  ? 99.181  107.177 67.733  1.00 34.15  ? 44  GLY D C   1 
ATOM   6324  O  O   . GLY D 1 44  ? 98.260  107.893 68.118  1.00 35.04  ? 44  GLY D O   1 
ATOM   6325  N  N   . ASN D 1 45  ? 99.738  107.303 66.534  1.00 27.48  ? 45  ASN D N   1 
ATOM   6326  C  CA  . ASN D 1 45  ? 99.275  108.291 65.578  1.00 33.82  ? 45  ASN D CA  1 
ATOM   6327  C  C   . ASN D 1 45  ? 98.200  107.703 64.669  1.00 33.87  ? 45  ASN D C   1 
ATOM   6328  O  O   . ASN D 1 45  ? 98.297  106.555 64.224  1.00 30.81  ? 45  ASN D O   1 
ATOM   6329  C  CB  . ASN D 1 45  ? 100.451 108.815 64.755  1.00 37.15  ? 45  ASN D CB  1 
ATOM   6330  C  CG  . ASN D 1 45  ? 101.566 109.361 65.632  1.00 40.45  ? 45  ASN D CG  1 
ATOM   6331  O  OD1 . ASN D 1 45  ? 101.326 110.205 66.490  1.00 39.77  ? 45  ASN D OD1 1 
ATOM   6332  N  ND2 . ASN D 1 45  ? 102.780 108.836 65.458  1.00 41.74  ? 45  ASN D ND2 1 
ATOM   6333  N  N   . VAL D 1 46  ? 97.187  108.517 64.383  1.00 33.38  ? 46  VAL D N   1 
ATOM   6334  C  CA  . VAL D 1 46  ? 96.025  108.130 63.591  1.00 31.11  ? 46  VAL D CA  1 
ATOM   6335  C  C   . VAL D 1 46  ? 95.944  109.045 62.380  1.00 31.90  ? 46  VAL D C   1 
ATOM   6336  O  O   . VAL D 1 46  ? 95.993  110.272 62.522  1.00 33.11  ? 46  VAL D O   1 
ATOM   6337  C  CB  . VAL D 1 46  ? 94.726  108.220 64.416  1.00 29.99  ? 46  VAL D CB  1 
ATOM   6338  C  CG1 . VAL D 1 46  ? 93.514  107.767 63.579  1.00 31.91  ? 46  VAL D CG1 1 
ATOM   6339  C  CG2 . VAL D 1 46  ? 94.856  107.412 65.707  1.00 29.65  ? 46  VAL D CG2 1 
ATOM   6340  N  N   . VAL D 1 47  ? 95.801  108.452 61.199  1.00 32.41  ? 47  VAL D N   1 
ATOM   6341  C  CA  . VAL D 1 47  ? 95.580  109.182 59.954  1.00 34.92  ? 47  VAL D CA  1 
ATOM   6342  C  C   . VAL D 1 47  ? 94.175  108.870 59.455  1.00 31.40  ? 47  VAL D C   1 
ATOM   6343  O  O   . VAL D 1 47  ? 93.783  107.699 59.379  1.00 30.86  ? 47  VAL D O   1 
ATOM   6344  C  CB  . VAL D 1 47  ? 96.626  108.807 58.889  1.00 30.85  ? 47  VAL D CB  1 
ATOM   6345  C  CG1 . VAL D 1 47  ? 96.194  109.312 57.500  1.00 32.04  ? 47  VAL D CG1 1 
ATOM   6346  C  CG2 . VAL D 1 47  ? 97.995  109.343 59.272  1.00 33.95  ? 47  VAL D CG2 1 
ATOM   6347  N  N   . ILE D 1 48  ? 93.424  109.905 59.103  1.00 34.62  ? 48  ILE D N   1 
ATOM   6348  C  CA  . ILE D 1 48  ? 92.074  109.738 58.575  1.00 31.12  ? 48  ILE D CA  1 
ATOM   6349  C  C   . ILE D 1 48  ? 92.127  110.005 57.070  1.00 32.01  ? 48  ILE D C   1 
ATOM   6350  O  O   . ILE D 1 48  ? 92.439  111.122 56.634  1.00 31.26  ? 48  ILE D O   1 
ATOM   6351  C  CB  . ILE D 1 48  ? 91.063  110.644 59.297  1.00 28.71  ? 48  ILE D CB  1 
ATOM   6352  C  CG1 . ILE D 1 48  ? 90.964  110.251 60.774  1.00 30.51  ? 48  ILE D CG1 1 
ATOM   6353  C  CG2 . ILE D 1 48  ? 89.697  110.558 58.637  1.00 27.33  ? 48  ILE D CG2 1 
ATOM   6354  C  CD1 . ILE D 1 48  ? 89.958  111.062 61.595  1.00 25.64  ? 48  ILE D CD1 1 
ATOM   6355  N  N   . ASP D 1 49  ? 91.869  108.953 56.283  1.00 27.71  ? 49  ASP D N   1 
ATOM   6356  C  CA  . ASP D 1 49  ? 91.733  108.990 54.821  1.00 30.35  ? 49  ASP D CA  1 
ATOM   6357  C  C   . ASP D 1 49  ? 93.042  109.253 54.077  1.00 32.18  ? 49  ASP D C   1 
ATOM   6358  O  O   . ASP D 1 49  ? 93.459  108.428 53.250  1.00 32.31  ? 49  ASP D O   1 
ATOM   6359  C  CB  . ASP D 1 49  ? 90.679  110.017 54.400  1.00 27.52  ? 49  ASP D CB  1 
ATOM   6360  C  CG  . ASP D 1 49  ? 89.245  109.531 54.665  1.00 32.67  ? 49  ASP D CG  1 
ATOM   6361  O  OD1 . ASP D 1 49  ? 89.036  108.302 54.798  1.00 31.04  ? 49  ASP D OD1 1 
ATOM   6362  O  OD2 . ASP D 1 49  ? 88.324  110.374 54.747  1.00 31.16  ? 49  ASP D OD2 1 
ATOM   6363  N  N   . GLY D 1 50  ? 93.675  110.402 54.318  1.00 35.88  ? 50  GLY D N   1 
ATOM   6364  C  CA  . GLY D 1 50  ? 94.942  110.720 53.672  1.00 34.58  ? 50  GLY D CA  1 
ATOM   6365  C  C   . GLY D 1 50  ? 94.859  111.472 52.359  1.00 37.62  ? 50  GLY D C   1 
ATOM   6366  O  O   . GLY D 1 50  ? 95.891  111.630 51.696  1.00 39.95  ? 50  GLY D O   1 
ATOM   6367  N  N   . GLY D 1 51  ? 93.676  111.939 51.955  1.00 35.83  ? 51  GLY D N   1 
ATOM   6368  C  CA  . GLY D 1 51  ? 93.560  112.742 50.754  1.00 33.23  ? 51  GLY D CA  1 
ATOM   6369  C  C   . GLY D 1 51  ? 93.757  111.942 49.472  1.00 36.48  ? 51  GLY D C   1 
ATOM   6370  O  O   . GLY D 1 51  ? 93.671  110.704 49.439  1.00 35.73  ? 51  GLY D O   1 
ATOM   6371  N  N   . CYS D 1 52  ? 93.997  112.672 48.390  1.00 28.58  ? 52  CYS D N   1 
ATOM   6372  C  CA  . CYS D 1 52  ? 94.212  112.002 47.116  1.00 36.54  ? 52  CYS D CA  1 
ATOM   6373  C  C   . CYS D 1 52  ? 95.593  111.368 47.118  1.00 34.59  ? 52  CYS D C   1 
ATOM   6374  O  O   . CYS D 1 52  ? 96.516  111.853 47.777  1.00 36.49  ? 52  CYS D O   1 
ATOM   6375  C  CB  . CYS D 1 52  ? 94.085  112.974 45.938  1.00 34.51  ? 52  CYS D CB  1 
ATOM   6376  S  SG  . CYS D 1 52  ? 92.656  114.077 45.951  1.00 38.68  ? 52  CYS D SG  1 
ATOM   6377  N  N   . ALA D 1 53  ? 95.721  110.258 46.391  1.00 34.63  ? 53  ALA D N   1 
ATOM   6378  C  CA  . ALA D 1 53  ? 97.011  109.585 46.294  1.00 36.23  ? 53  ALA D CA  1 
ATOM   6379  C  C   . ALA D 1 53  ? 98.056  110.543 45.737  1.00 42.46  ? 53  ALA D C   1 
ATOM   6380  O  O   . ALA D 1 53  ? 97.784  111.303 44.801  1.00 38.33  ? 53  ALA D O   1 
ATOM   6381  C  CB  . ALA D 1 53  ? 96.905  108.357 45.401  1.00 39.09  ? 53  ALA D CB  1 
ATOM   6382  N  N   . VAL D 1 54  ? 99.259  110.513 46.318  1.00 43.03  ? 54  VAL D N   1 
ATOM   6383  C  CA  . VAL D 1 54  ? 100.306 111.432 45.877  1.00 45.67  ? 54  VAL D CA  1 
ATOM   6384  C  C   . VAL D 1 54  ? 100.630 111.245 44.396  1.00 45.01  ? 54  VAL D C   1 
ATOM   6385  O  O   . VAL D 1 54  ? 101.083 112.190 43.741  1.00 46.00  ? 54  VAL D O   1 
ATOM   6386  C  CB  . VAL D 1 54  ? 101.561 111.291 46.770  1.00 46.36  ? 54  VAL D CB  1 
ATOM   6387  C  CG1 . VAL D 1 54  ? 102.226 109.933 46.582  1.00 42.10  ? 54  VAL D CG1 1 
ATOM   6388  C  CG2 . VAL D 1 54  ? 102.525 112.440 46.509  1.00 43.32  ? 54  VAL D CG2 1 
ATOM   6389  N  N   . GLU D 1 55  ? 100.347 110.062 43.834  1.00 42.39  ? 55  GLU D N   1 
ATOM   6390  C  CA  . GLU D 1 55  ? 100.509 109.852 42.397  1.00 48.12  ? 55  GLU D CA  1 
ATOM   6391  C  C   . GLU D 1 55  ? 99.717  110.856 41.566  1.00 53.27  ? 55  GLU D C   1 
ATOM   6392  O  O   . GLU D 1 55  ? 100.055 111.077 40.395  1.00 50.16  ? 55  GLU D O   1 
ATOM   6393  C  CB  . GLU D 1 55  ? 100.085 108.432 42.009  1.00 45.69  ? 55  GLU D CB  1 
ATOM   6394  C  CG  . GLU D 1 55  ? 101.074 107.342 42.372  1.00 43.48  ? 55  GLU D CG  1 
ATOM   6395  C  CD  . GLU D 1 55  ? 101.048 106.971 43.847  1.00 48.17  ? 55  GLU D CD  1 
ATOM   6396  O  OE1 . GLU D 1 55  ? 100.378 107.673 44.648  1.00 44.34  ? 55  GLU D OE1 1 
ATOM   6397  O  OE2 . GLU D 1 55  ? 101.711 105.972 44.206  1.00 46.16  ? 55  GLU D OE2 1 
ATOM   6398  N  N   . CYS D 1 56  ? 98.676  111.467 42.142  1.00 47.39  ? 56  CYS D N   1 
ATOM   6399  C  CA  . CYS D 1 56  ? 97.852  112.409 41.394  1.00 47.09  ? 56  CYS D CA  1 
ATOM   6400  C  C   . CYS D 1 56  ? 98.540  113.748 41.190  1.00 52.22  ? 56  CYS D C   1 
ATOM   6401  O  O   . CYS D 1 56  ? 98.130  114.516 40.309  1.00 51.88  ? 56  CYS D O   1 
ATOM   6402  C  CB  . CYS D 1 56  ? 96.520  112.619 42.110  1.00 46.99  ? 56  CYS D CB  1 
ATOM   6403  S  SG  . CYS D 1 56  ? 95.640  111.069 42.396  1.00 47.66  ? 56  CYS D SG  1 
ATOM   6404  N  N   . ALA D 1 57  ? 99.569  114.049 41.987  1.00 49.81  ? 57  ALA D N   1 
ATOM   6405  C  CA  . ALA D 1 57  ? 100.310 115.290 41.799  1.00 54.84  ? 57  ALA D CA  1 
ATOM   6406  C  C   . ALA D 1 57  ? 101.120 115.276 40.512  1.00 53.65  ? 57  ALA D C   1 
ATOM   6407  O  O   . ALA D 1 57  ? 101.426 116.347 39.976  1.00 52.72  ? 57  ALA D O   1 
ATOM   6408  C  CB  . ALA D 1 57  ? 101.236 115.541 42.994  1.00 54.32  ? 57  ALA D CB  1 
ATOM   6409  N  N   . SER D 1 58  ? 101.455 114.086 40.010  1.00 51.62  ? 58  SER D N   1 
ATOM   6410  C  CA  . SER D 1 58  ? 102.260 113.915 38.809  1.00 55.20  ? 58  SER D CA  1 
ATOM   6411  C  C   . SER D 1 58  ? 101.425 113.455 37.622  1.00 56.02  ? 58  SER D C   1 
ATOM   6412  O  O   . SER D 1 58  ? 101.397 114.123 36.584  1.00 60.54  ? 58  SER D O   1 
ATOM   6413  C  CB  . SER D 1 58  ? 103.388 112.907 39.081  1.00 51.85  ? 58  SER D CB  1 
ATOM   6414  O  OG  . SER D 1 58  ? 104.109 113.261 40.247  1.00 57.49  ? 58  SER D OG  1 
ATOM   6415  N  N   . ASP D 1 59  ? 100.742 112.319 37.746  1.00 55.09  ? 59  ASP D N   1 
ATOM   6416  C  CA  . ASP D 1 59  ? 100.020 111.698 36.636  1.00 53.65  ? 59  ASP D CA  1 
ATOM   6417  C  C   . ASP D 1 59  ? 98.569  111.447 37.036  1.00 52.63  ? 59  ASP D C   1 
ATOM   6418  O  O   . ASP D 1 59  ? 98.168  110.305 37.299  1.00 52.07  ? 59  ASP D O   1 
ATOM   6419  C  CB  . ASP D 1 59  ? 100.711 110.402 36.215  1.00 53.78  ? 59  ASP D CB  1 
ATOM   6420  C  CG  . ASP D 1 59  ? 100.268 109.919 34.853  1.00 50.33  ? 59  ASP D CG  1 
ATOM   6421  O  OD1 . ASP D 1 59  ? 99.554  110.673 34.153  1.00 53.18  ? 59  ASP D OD1 1 
ATOM   6422  O  OD2 . ASP D 1 59  ? 100.637 108.785 34.487  1.00 55.90  ? 59  ASP D OD2 1 
ATOM   6423  N  N   . PRO D 1 60  ? 97.752  112.501 37.092  1.00 50.96  ? 60  PRO D N   1 
ATOM   6424  C  CA  . PRO D 1 60  ? 96.329  112.296 37.426  1.00 50.13  ? 60  PRO D CA  1 
ATOM   6425  C  C   . PRO D 1 60  ? 95.619  111.370 36.453  1.00 50.21  ? 60  PRO D C   1 
ATOM   6426  O  O   . PRO D 1 60  ? 94.926  110.438 36.878  1.00 48.18  ? 60  PRO D O   1 
ATOM   6427  C  CB  . PRO D 1 60  ? 95.742  113.714 37.381  1.00 52.35  ? 60  PRO D CB  1 
ATOM   6428  C  CG  . PRO D 1 60  ? 96.898  114.646 37.399  1.00 52.83  ? 60  PRO D CG  1 
ATOM   6429  C  CD  . PRO D 1 60  ? 98.101  113.918 36.910  1.00 53.07  ? 60  PRO D CD  1 
ATOM   6430  N  N   . LYS D 1 61  ? 95.772  111.607 35.149  1.00 48.60  ? 61  LYS D N   1 
ATOM   6431  C  CA  . LYS D 1 61  ? 95.081  110.787 34.163  1.00 49.41  ? 61  LYS D CA  1 
ATOM   6432  C  C   . LYS D 1 61  ? 95.578  109.353 34.203  1.00 49.83  ? 61  LYS D C   1 
ATOM   6433  O  O   . LYS D 1 61  ? 94.803  108.413 33.983  1.00 51.31  ? 61  LYS D O   1 
ATOM   6434  C  CB  . LYS D 1 61  ? 95.264  111.364 32.763  1.00 53.81  ? 61  LYS D CB  1 
ATOM   6435  C  CG  . LYS D 1 61  ? 94.515  112.656 32.492  1.00 59.77  ? 61  LYS D CG  1 
ATOM   6436  C  CD  . LYS D 1 61  ? 94.530  112.953 30.999  1.00 65.52  ? 61  LYS D CD  1 
ATOM   6437  C  CE  . LYS D 1 61  ? 94.139  114.390 30.701  1.00 69.20  ? 61  LYS D CE  1 
ATOM   6438  N  NZ  . LYS D 1 61  ? 94.169  114.653 29.231  1.00 72.15  ? 61  LYS D NZ  1 
ATOM   6439  N  N   . GLY D 1 62  ? 96.868  109.163 34.489  1.00 46.98  ? 62  GLY D N   1 
ATOM   6440  C  CA  . GLY D 1 62  ? 97.416  107.818 34.494  1.00 48.07  ? 62  GLY D CA  1 
ATOM   6441  C  C   . GLY D 1 62  ? 96.985  107.001 35.696  1.00 51.51  ? 62  GLY D C   1 
ATOM   6442  O  O   . GLY D 1 62  ? 96.766  105.789 35.586  1.00 48.62  ? 62  GLY D O   1 
ATOM   6443  N  N   . TYR D 1 63  ? 96.849  107.644 36.852  1.00 46.78  ? 63  TYR D N   1 
ATOM   6444  C  CA  . TYR D 1 63  ? 96.542  106.915 38.073  1.00 48.06  ? 63  TYR D CA  1 
ATOM   6445  C  C   . TYR D 1 63  ? 95.037  106.807 38.338  1.00 46.84  ? 63  TYR D C   1 
ATOM   6446  O  O   . TYR D 1 63  ? 94.568  105.766 38.807  1.00 45.21  ? 63  TYR D O   1 
ATOM   6447  C  CB  . TYR D 1 63  ? 97.252  107.574 39.259  1.00 47.28  ? 63  TYR D CB  1 
ATOM   6448  C  CG  . TYR D 1 63  ? 97.257  106.702 40.479  1.00 49.86  ? 63  TYR D CG  1 
ATOM   6449  C  CD1 . TYR D 1 63  ? 97.922  105.483 40.472  1.00 48.29  ? 63  TYR D CD1 1 
ATOM   6450  C  CD2 . TYR D 1 63  ? 96.567  107.077 41.634  1.00 46.54  ? 63  TYR D CD2 1 
ATOM   6451  C  CE1 . TYR D 1 63  ? 97.918  104.668 41.587  1.00 50.40  ? 63  TYR D CE1 1 
ATOM   6452  C  CE2 . TYR D 1 63  ? 96.555  106.262 42.752  1.00 41.69  ? 63  TYR D CE2 1 
ATOM   6453  C  CZ  . TYR D 1 63  ? 97.231  105.064 42.724  1.00 45.25  ? 63  TYR D CZ  1 
ATOM   6454  O  OH  . TYR D 1 63  ? 97.228  104.243 43.825  1.00 39.42  ? 63  TYR D OH  1 
ATOM   6455  N  N   . TRP D 1 64  ? 94.261  107.851 38.033  1.00 48.89  ? 64  TRP D N   1 
ATOM   6456  C  CA  . TRP D 1 64  ? 92.818  107.841 38.263  1.00 44.14  ? 64  TRP D CA  1 
ATOM   6457  C  C   . TRP D 1 64  ? 92.038  107.385 37.027  1.00 47.29  ? 64  TRP D C   1 
ATOM   6458  O  O   . TRP D 1 64  ? 91.116  106.572 37.140  1.00 50.68  ? 64  TRP D O   1 
ATOM   6459  C  CB  . TRP D 1 64  ? 92.345  109.231 38.702  1.00 36.64  ? 64  TRP D CB  1 
ATOM   6460  C  CG  . TRP D 1 64  ? 92.466  109.532 40.188  1.00 40.01  ? 64  TRP D CG  1 
ATOM   6461  C  CD1 . TRP D 1 64  ? 93.041  108.749 41.151  1.00 35.83  ? 64  TRP D CD1 1 
ATOM   6462  C  CD2 . TRP D 1 64  ? 91.997  110.712 40.862  1.00 35.98  ? 64  TRP D CD2 1 
ATOM   6463  N  NE1 . TRP D 1 64  ? 92.957  109.368 42.379  1.00 34.00  ? 64  TRP D NE1 1 
ATOM   6464  C  CE2 . TRP D 1 64  ? 92.326  110.574 42.228  1.00 33.81  ? 64  TRP D CE2 1 
ATOM   6465  C  CE3 . TRP D 1 64  ? 91.340  111.872 40.440  1.00 34.32  ? 64  TRP D CE3 1 
ATOM   6466  C  CZ2 . TRP D 1 64  ? 92.013  111.549 43.177  1.00 35.87  ? 64  TRP D CZ2 1 
ATOM   6467  C  CZ3 . TRP D 1 64  ? 91.022  112.844 41.390  1.00 38.06  ? 64  TRP D CZ3 1 
ATOM   6468  C  CH2 . TRP D 1 64  ? 91.366  112.677 42.739  1.00 35.15  ? 64  TRP D CH2 1 
ATOM   6469  N  N   . GLY D 1 65  ? 92.385  107.897 35.846  1.00 48.43  ? 65  GLY D N   1 
ATOM   6470  C  CA  . GLY D 1 65  ? 91.694  107.481 34.640  1.00 44.69  ? 65  GLY D CA  1 
ATOM   6471  C  C   . GLY D 1 65  ? 90.604  108.438 34.197  1.00 45.67  ? 65  GLY D C   1 
ATOM   6472  O  O   . GLY D 1 65  ? 90.660  109.636 34.495  1.00 46.72  ? 65  GLY D O   1 
ATOM   6473  N  N   . ASP D 1 66  ? 89.597  107.908 33.493  1.00 45.91  ? 66  ASP D N   1 
ATOM   6474  C  CA  . ASP D 1 66  ? 88.545  108.732 32.897  1.00 47.27  ? 66  ASP D CA  1 
ATOM   6475  C  C   . ASP D 1 66  ? 87.924  109.705 33.892  1.00 48.03  ? 66  ASP D C   1 
ATOM   6476  O  O   . ASP D 1 66  ? 87.511  110.807 33.511  1.00 50.57  ? 66  ASP D O   1 
ATOM   6477  C  CB  . ASP D 1 66  ? 87.446  107.835 32.315  1.00 55.42  ? 66  ASP D CB  1 
ATOM   6478  C  CG  . ASP D 1 66  ? 87.883  107.095 31.055  1.00 61.76  ? 66  ASP D CG  1 
ATOM   6479  O  OD1 . ASP D 1 66  ? 89.000  107.353 30.544  1.00 60.86  ? 66  ASP D OD1 1 
ATOM   6480  O  OD2 . ASP D 1 66  ? 87.104  106.226 30.595  1.00 58.25  ? 66  ASP D OD2 1 
ATOM   6481  N  N   . ILE D 1 67  ? 87.856  109.325 35.170  1.00 47.46  ? 67  ILE D N   1 
ATOM   6482  C  CA  . ILE D 1 67  ? 87.202  110.154 36.176  1.00 47.09  ? 67  ILE D CA  1 
ATOM   6483  C  C   . ILE D 1 67  ? 87.823  111.543 36.287  1.00 50.63  ? 67  ILE D C   1 
ATOM   6484  O  O   . ILE D 1 67  ? 87.192  112.448 36.848  1.00 50.00  ? 67  ILE D O   1 
ATOM   6485  C  CB  . ILE D 1 67  ? 87.220  109.430 37.544  1.00 47.77  ? 67  ILE D CB  1 
ATOM   6486  C  CG1 . ILE D 1 67  ? 86.217  110.064 38.514  1.00 44.59  ? 67  ILE D CG1 1 
ATOM   6487  C  CG2 . ILE D 1 67  ? 88.630  109.422 38.141  1.00 43.10  ? 67  ILE D CG2 1 
ATOM   6488  C  CD1 . ILE D 1 67  ? 84.771  109.766 38.185  1.00 48.46  ? 67  ILE D CD1 1 
ATOM   6489  N  N   . THR D 1 68  ? 89.047  111.744 35.759  1.00 50.86  ? 68  THR D N   1 
ATOM   6490  C  CA  . THR D 1 68  ? 89.686  113.063 35.815  1.00 48.49  ? 68  THR D CA  1 
ATOM   6491  C  C   . THR D 1 68  ? 88.940  114.111 34.999  1.00 47.87  ? 68  THR D C   1 
ATOM   6492  O  O   . THR D 1 68  ? 89.162  115.307 35.206  1.00 50.63  ? 68  THR D O   1 
ATOM   6493  C  CB  . THR D 1 68  ? 91.148  113.003 35.344  1.00 46.81  ? 68  THR D CB  1 
ATOM   6494  O  OG1 . THR D 1 68  ? 91.209  112.570 33.986  1.00 50.76  ? 68  THR D OG1 1 
ATOM   6495  C  CG2 . THR D 1 68  ? 91.970  112.047 36.196  1.00 49.02  ? 68  THR D CG2 1 
ATOM   6496  N  N   . SER D 1 69  ? 88.063  113.696 34.082  1.00 47.56  ? 69  SER D N   1 
ATOM   6497  C  CA  . SER D 1 69  ? 87.199  114.646 33.390  1.00 46.53  ? 69  SER D CA  1 
ATOM   6498  C  C   . SER D 1 69  ? 86.101  115.216 34.289  1.00 51.77  ? 69  SER D C   1 
ATOM   6499  O  O   . SER D 1 69  ? 85.498  116.239 33.937  1.00 48.17  ? 69  SER D O   1 
ATOM   6500  C  CB  . SER D 1 69  ? 86.577  113.973 32.169  1.00 52.28  ? 69  SER D CB  1 
ATOM   6501  O  OG  . SER D 1 69  ? 85.409  113.245 32.519  1.00 58.36  ? 69  SER D OG  1 
ATOM   6502  N  N   . VAL D 1 70  ? 85.820  114.583 35.427  1.00 52.51  ? 70  VAL D N   1 
ATOM   6503  C  CA  . VAL D 1 70  ? 84.874  115.109 36.407  1.00 48.48  ? 70  VAL D CA  1 
ATOM   6504  C  C   . VAL D 1 70  ? 85.594  115.757 37.579  1.00 47.30  ? 70  VAL D C   1 
ATOM   6505  O  O   . VAL D 1 70  ? 85.201  116.827 38.043  1.00 45.04  ? 70  VAL D O   1 
ATOM   6506  C  CB  . VAL D 1 70  ? 83.924  113.998 36.907  1.00 49.92  ? 70  VAL D CB  1 
ATOM   6507  C  CG1 . VAL D 1 70  ? 82.957  114.558 37.938  1.00 48.47  ? 70  VAL D CG1 1 
ATOM   6508  C  CG2 . VAL D 1 70  ? 83.165  113.376 35.751  1.00 49.12  ? 70  VAL D CG2 1 
ATOM   6509  N  N   . TYR D 1 71  ? 86.648  115.107 38.064  1.00 50.03  ? 71  TYR D N   1 
ATOM   6510  C  CA  . TYR D 1 71  ? 87.408  115.557 39.227  1.00 50.78  ? 71  TYR D CA  1 
ATOM   6511  C  C   . TYR D 1 71  ? 88.862  115.710 38.802  1.00 45.87  ? 71  TYR D C   1 
ATOM   6512  O  O   . TYR D 1 71  ? 89.555  114.712 38.575  1.00 45.86  ? 71  TYR D O   1 
ATOM   6513  C  CB  . TYR D 1 71  ? 87.258  114.564 40.384  1.00 48.80  ? 71  TYR D CB  1 
ATOM   6514  C  CG  . TYR D 1 71  ? 85.832  114.463 40.891  1.00 51.01  ? 71  TYR D CG  1 
ATOM   6515  C  CD1 . TYR D 1 71  ? 85.257  115.504 41.620  1.00 45.59  ? 71  TYR D CD1 1 
ATOM   6516  C  CD2 . TYR D 1 71  ? 85.049  113.344 40.618  1.00 51.09  ? 71  TYR D CD2 1 
ATOM   6517  C  CE1 . TYR D 1 71  ? 83.955  115.420 42.083  1.00 46.84  ? 71  TYR D CE1 1 
ATOM   6518  C  CE2 . TYR D 1 71  ? 83.733  113.258 41.077  1.00 50.08  ? 71  TYR D CE2 1 
ATOM   6519  C  CZ  . TYR D 1 71  ? 83.198  114.299 41.808  1.00 46.81  ? 71  TYR D CZ  1 
ATOM   6520  O  OH  . TYR D 1 71  ? 81.902  114.224 42.265  1.00 50.59  ? 71  TYR D OH  1 
ATOM   6521  N  N   . TRP D 1 72  ? 89.317  116.954 38.669  1.00 47.03  ? 72  TRP D N   1 
ATOM   6522  C  CA  . TRP D 1 72  ? 90.713  117.196 38.345  1.00 47.10  ? 72  TRP D CA  1 
ATOM   6523  C  C   . TRP D 1 72  ? 91.481  117.547 39.610  1.00 42.24  ? 72  TRP D C   1 
ATOM   6524  O  O   . TRP D 1 72  ? 91.166  118.553 40.268  1.00 41.69  ? 72  TRP D O   1 
ATOM   6525  C  CB  . TRP D 1 72  ? 90.866  118.306 37.311  1.00 46.45  ? 72  TRP D CB  1 
ATOM   6526  C  CG  . TRP D 1 72  ? 92.309  118.485 36.978  1.00 50.39  ? 72  TRP D CG  1 
ATOM   6527  C  CD1 . TRP D 1 72  ? 93.160  119.440 37.470  1.00 48.80  ? 72  TRP D CD1 1 
ATOM   6528  C  CD2 . TRP D 1 72  ? 93.104  117.627 36.153  1.00 49.93  ? 72  TRP D CD2 1 
ATOM   6529  N  NE1 . TRP D 1 72  ? 94.426  119.242 36.972  1.00 50.82  ? 72  TRP D NE1 1 
ATOM   6530  C  CE2 . TRP D 1 72  ? 94.416  118.138 36.160  1.00 49.48  ? 72  TRP D CE2 1 
ATOM   6531  C  CE3 . TRP D 1 72  ? 92.829  116.487 35.392  1.00 52.15  ? 72  TRP D CE3 1 
ATOM   6532  C  CZ2 . TRP D 1 72  ? 95.447  117.550 35.434  1.00 51.39  ? 72  TRP D CZ2 1 
ATOM   6533  C  CZ3 . TRP D 1 72  ? 93.856  115.904 34.677  1.00 55.85  ? 72  TRP D CZ3 1 
ATOM   6534  C  CH2 . TRP D 1 72  ? 95.149  116.436 34.704  1.00 51.72  ? 72  TRP D CH2 1 
ATOM   6535  N  N   . PRO D 1 73  ? 92.480  116.775 39.977  1.00 42.01  ? 73  PRO D N   1 
ATOM   6536  C  CA  . PRO D 1 73  ? 93.202  117.065 41.215  1.00 46.40  ? 73  PRO D CA  1 
ATOM   6537  C  C   . PRO D 1 73  ? 94.354  118.033 40.994  1.00 48.07  ? 73  PRO D C   1 
ATOM   6538  O  O   . PRO D 1 73  ? 95.246  117.791 40.175  1.00 46.66  ? 73  PRO D O   1 
ATOM   6539  C  CB  . PRO D 1 73  ? 93.696  115.681 41.664  1.00 43.47  ? 73  PRO D CB  1 
ATOM   6540  C  CG  . PRO D 1 73  ? 93.757  114.852 40.412  1.00 42.59  ? 73  PRO D CG  1 
ATOM   6541  C  CD  . PRO D 1 73  ? 92.993  115.569 39.307  1.00 42.23  ? 73  PRO D CD  1 
ATOM   6542  N  N   . VAL D 1 74  ? 94.337  119.132 41.733  1.00 46.93  ? 74  VAL D N   1 
ATOM   6543  C  CA  . VAL D 1 74  ? 95.432  120.090 41.756  1.00 46.25  ? 74  VAL D CA  1 
ATOM   6544  C  C   . VAL D 1 74  ? 96.164  119.895 43.077  1.00 46.10  ? 74  VAL D C   1 
ATOM   6545  O  O   . VAL D 1 74  ? 95.648  120.257 44.140  1.00 48.23  ? 74  VAL D O   1 
ATOM   6546  C  CB  . VAL D 1 74  ? 94.916  121.526 41.589  1.00 48.94  ? 74  VAL D CB  1 
ATOM   6547  C  CG1 . VAL D 1 74  ? 96.072  122.519 41.520  1.00 49.56  ? 74  VAL D CG1 1 
ATOM   6548  C  CG2 . VAL D 1 74  ? 94.035  121.619 40.343  1.00 46.49  ? 74  VAL D CG2 1 
ATOM   6549  N  N   . MET D 1 75  ? 97.355  119.302 43.029  1.00 47.62  ? 75  MET D N   1 
ATOM   6550  C  CA  . MET D 1 75  ? 98.131  119.110 44.249  1.00 52.79  ? 75  MET D CA  1 
ATOM   6551  C  C   . MET D 1 75  ? 99.609  118.934 43.911  1.00 52.81  ? 75  MET D C   1 
ATOM   6552  O  O   . MET D 1 75  ? 99.964  118.439 42.838  1.00 49.85  ? 75  MET D O   1 
ATOM   6553  C  CB  . MET D 1 75  ? 97.608  117.912 45.068  1.00 48.93  ? 75  MET D CB  1 
ATOM   6554  C  CG  . MET D 1 75  ? 97.933  116.526 44.509  1.00 47.88  ? 75  MET D CG  1 
ATOM   6555  S  SD  . MET D 1 75  ? 97.514  115.128 45.600  1.00 48.53  ? 75  MET D SD  1 
ATOM   6556  C  CE  . MET D 1 75  ? 98.569  115.394 47.025  1.00 44.00  ? 75  MET D CE  1 
ATOM   6557  N  N   . ARG D 1 76  ? 100.460 119.353 44.844  1.00 51.49  ? 76  ARG D N   1 
ATOM   6558  C  CA  . ARG D 1 76  ? 101.898 119.165 44.742  1.00 55.21  ? 76  ARG D CA  1 
ATOM   6559  C  C   . ARG D 1 76  ? 102.297 117.828 45.358  1.00 54.90  ? 76  ARG D C   1 
ATOM   6560  O  O   . ARG D 1 76  ? 101.538 117.218 46.118  1.00 56.24  ? 76  ARG D O   1 
ATOM   6561  C  CB  . ARG D 1 76  ? 102.636 120.313 45.432  1.00 54.15  ? 76  ARG D CB  1 
ATOM   6562  C  CG  . ARG D 1 76  ? 102.251 121.680 44.921  1.00 51.94  ? 76  ARG D CG  1 
ATOM   6563  C  CD  . ARG D 1 76  ? 102.792 122.785 45.830  1.00 60.21  ? 76  ARG D CD  1 
ATOM   6564  N  NE  . ARG D 1 76  ? 101.784 123.265 46.772  1.00 60.31  ? 76  ARG D NE  1 
ATOM   6565  C  CZ  . ARG D 1 76  ? 101.903 123.219 48.094  1.00 63.97  ? 76  ARG D CZ  1 
ATOM   6566  N  NH1 . ARG D 1 76  ? 102.991 122.736 48.676  1.00 61.76  ? 76  ARG D NH1 1 
ATOM   6567  N  NH2 . ARG D 1 76  ? 100.906 123.676 48.852  1.00 59.69  ? 76  ARG D NH2 1 
ATOM   6568  N  N   . ILE D 1 77  ? 103.508 117.373 45.016  1.00 56.17  ? 77  ILE D N   1 
ATOM   6569  C  CA  . ILE D 1 77  ? 103.987 116.078 45.500  1.00 55.66  ? 77  ILE D CA  1 
ATOM   6570  C  C   . ILE D 1 77  ? 104.177 116.109 47.012  1.00 53.30  ? 77  ILE D C   1 
ATOM   6571  O  O   . ILE D 1 77  ? 103.828 115.153 47.715  1.00 54.17  ? 77  ILE D O   1 
ATOM   6572  C  CB  . ILE D 1 77  ? 105.288 115.671 44.779  1.00 59.42  ? 77  ILE D CB  1 
ATOM   6573  C  CG1 . ILE D 1 77  ? 104.984 114.903 43.494  1.00 58.85  ? 77  ILE D CG1 1 
ATOM   6574  C  CG2 . ILE D 1 77  ? 106.163 114.799 45.673  1.00 59.41  ? 77  ILE D CG2 1 
ATOM   6575  C  CD1 . ILE D 1 77  ? 106.232 114.500 42.732  1.00 62.68  ? 77  ILE D CD1 1 
ATOM   6576  N  N   . GLU D 1 78  ? 104.726 117.202 47.539  1.00 55.63  ? 78  GLU D N   1 
ATOM   6577  C  CA  . GLU D 1 78  ? 104.967 117.270 48.976  1.00 56.99  ? 78  GLU D CA  1 
ATOM   6578  C  C   . GLU D 1 78  ? 103.677 117.265 49.785  1.00 56.80  ? 78  GLU D C   1 
ATOM   6579  O  O   . GLU D 1 78  ? 103.735 117.059 51.002  1.00 57.67  ? 78  GLU D O   1 
ATOM   6580  C  CB  . GLU D 1 78  ? 105.794 118.513 49.325  1.00 61.97  ? 78  GLU D CB  1 
ATOM   6581  C  CG  . GLU D 1 78  ? 105.003 119.812 49.380  1.00 61.23  ? 78  GLU D CG  1 
ATOM   6582  C  CD  . GLU D 1 78  ? 105.429 120.801 48.315  1.00 69.26  ? 78  GLU D CD  1 
ATOM   6583  O  OE1 . GLU D 1 78  ? 105.462 120.424 47.120  1.00 68.53  ? 78  GLU D OE1 1 
ATOM   6584  O  OE2 . GLU D 1 78  ? 105.728 121.960 48.677  1.00 76.45  ? 78  GLU D OE2 1 
ATOM   6585  N  N   . GLU D 1 79  ? 102.522 117.469 49.142  1.00 55.99  ? 79  GLU D N   1 
ATOM   6586  C  CA  . GLU D 1 79  ? 101.230 117.418 49.817  1.00 55.59  ? 79  GLU D CA  1 
ATOM   6587  C  C   . GLU D 1 79  ? 100.713 115.999 50.041  1.00 51.42  ? 79  GLU D C   1 
ATOM   6588  O  O   . GLU D 1 79  ? 99.733  115.834 50.775  1.00 51.77  ? 79  GLU D O   1 
ATOM   6589  C  CB  . GLU D 1 79  ? 100.186 118.210 49.025  1.00 52.46  ? 79  GLU D CB  1 
ATOM   6590  C  CG  . GLU D 1 79  ? 100.309 119.713 49.153  1.00 52.27  ? 79  GLU D CG  1 
ATOM   6591  C  CD  . GLU D 1 79  ? 99.234  120.433 48.384  1.00 48.85  ? 79  GLU D CD  1 
ATOM   6592  O  OE1 . GLU D 1 79  ? 99.294  120.433 47.134  1.00 44.20  ? 79  GLU D OE1 1 
ATOM   6593  O  OE2 . GLU D 1 79  ? 98.327  120.992 49.038  1.00 45.67  ? 79  GLU D OE2 1 
ATOM   6594  N  N   . GLY D 1 80  ? 101.319 114.985 49.419  1.00 44.88  ? 80  GLY D N   1 
ATOM   6595  C  CA  . GLY D 1 80  ? 100.953 113.609 49.696  1.00 44.66  ? 80  GLY D CA  1 
ATOM   6596  C  C   . GLY D 1 80  ? 101.070 113.308 51.174  1.00 46.36  ? 80  GLY D C   1 
ATOM   6597  O  O   . GLY D 1 80  ? 101.903 113.916 51.853  1.00 46.15  ? 80  GLY D O   1 
ATOM   6598  N  N   . CYS D 1 81  ? 100.249 112.395 51.703  1.00 43.34  ? 81  CYS D N   1 
ATOM   6599  C  CA  . CYS D 1 81  ? 100.181 112.283 53.159  1.00 42.34  ? 81  CYS D CA  1 
ATOM   6600  C  C   . CYS D 1 81  ? 101.480 111.733 53.750  1.00 40.97  ? 81  CYS D C   1 
ATOM   6601  O  O   . CYS D 1 81  ? 101.882 112.148 54.841  1.00 46.30  ? 81  CYS D O   1 
ATOM   6602  C  CB  . CYS D 1 81  ? 98.971  111.436 53.583  1.00 37.47  ? 81  CYS D CB  1 
ATOM   6603  S  SG  . CYS D 1 81  ? 98.908  109.732 52.962  1.00 41.87  ? 81  CYS D SG  1 
ATOM   6604  N  N   . VAL D 1 82  ? 102.155 110.819 53.056  1.00 43.76  ? 82  VAL D N   1 
ATOM   6605  C  CA  . VAL D 1 82  ? 103.435 110.316 53.552  1.00 45.70  ? 82  VAL D CA  1 
ATOM   6606  C  C   . VAL D 1 82  ? 104.473 111.436 53.603  1.00 45.57  ? 82  VAL D C   1 
ATOM   6607  O  O   . VAL D 1 82  ? 105.212 111.573 54.584  1.00 45.06  ? 82  VAL D O   1 
ATOM   6608  C  CB  . VAL D 1 82  ? 103.922 109.139 52.689  1.00 41.61  ? 82  VAL D CB  1 
ATOM   6609  C  CG1 . VAL D 1 82  ? 105.291 108.668 53.165  1.00 46.44  ? 82  VAL D CG1 1 
ATOM   6610  C  CG2 . VAL D 1 82  ? 102.927 108.005 52.738  1.00 44.33  ? 82  VAL D CG2 1 
ATOM   6611  N  N   . GLN D 1 83  ? 104.533 112.260 52.557  1.00 44.34  ? 83  GLN D N   1 
ATOM   6612  C  CA  . GLN D 1 83  ? 105.528 113.326 52.494  1.00 48.22  ? 83  GLN D CA  1 
ATOM   6613  C  C   . GLN D 1 83  ? 105.260 114.406 53.543  1.00 48.62  ? 83  GLN D C   1 
ATOM   6614  O  O   . GLN D 1 83  ? 106.183 114.848 54.239  1.00 48.56  ? 83  GLN D O   1 
ATOM   6615  C  CB  . GLN D 1 83  ? 105.567 113.918 51.080  1.00 48.49  ? 83  GLN D CB  1 
ATOM   6616  C  CG  . GLN D 1 83  ? 105.800 112.901 49.925  1.00 51.81  ? 83  GLN D CG  1 
ATOM   6617  C  CD  . GLN D 1 83  ? 104.666 111.878 49.738  1.00 54.56  ? 83  GLN D CD  1 
ATOM   6618  O  OE1 . GLN D 1 83  ? 103.676 111.893 50.470  1.00 50.84  ? 83  GLN D OE1 1 
ATOM   6619  N  NE2 . GLN D 1 83  ? 104.819 110.987 48.761  1.00 51.62  ? 83  GLN D NE2 1 
ATOM   6620  N  N   . ALA D 1 84  ? 104.001 114.835 53.688  1.00 45.66  ? 84  ALA D N   1 
ATOM   6621  C  CA  . ALA D 1 84  ? 103.696 115.882 54.662  1.00 47.87  ? 84  ALA D CA  1 
ATOM   6622  C  C   . ALA D 1 84  ? 103.903 115.406 56.096  1.00 47.35  ? 84  ALA D C   1 
ATOM   6623  O  O   . ALA D 1 84  ? 104.238 116.212 56.971  1.00 49.47  ? 84  ALA D O   1 
ATOM   6624  C  CB  . ALA D 1 84  ? 102.262 116.392 54.477  1.00 46.41  ? 84  ALA D CB  1 
ATOM   6625  N  N   . LEU D 1 85  ? 103.712 114.114 56.366  1.00 44.68  ? 85  LEU D N   1 
ATOM   6626  C  CA  . LEU D 1 85  ? 103.926 113.637 57.728  1.00 50.34  ? 85  LEU D CA  1 
ATOM   6627  C  C   . LEU D 1 85  ? 105.417 113.565 58.063  1.00 49.13  ? 85  LEU D C   1 
ATOM   6628  O  O   . LEU D 1 85  ? 105.824 113.966 59.161  1.00 48.73  ? 85  LEU D O   1 
ATOM   6629  C  CB  . LEU D 1 85  ? 103.246 112.283 57.930  1.00 48.43  ? 85  LEU D CB  1 
ATOM   6630  C  CG  . LEU D 1 85  ? 101.732 112.318 58.210  1.00 49.79  ? 85  LEU D CG  1 
ATOM   6631  C  CD1 . LEU D 1 85  ? 101.196 110.907 58.414  1.00 44.42  ? 85  LEU D CD1 1 
ATOM   6632  C  CD2 . LEU D 1 85  ? 101.394 113.201 59.409  1.00 47.70  ? 85  LEU D CD2 1 
ATOM   6633  N  N   . LYS D 1 86  ? 106.241 113.049 57.141  1.00 42.07  ? 86  LYS D N   1 
ATOM   6634  C  CA  . LYS D 1 86  ? 107.695 113.110 57.301  1.00 47.85  ? 86  LYS D CA  1 
ATOM   6635  C  C   . LYS D 1 86  ? 108.152 114.531 57.614  1.00 48.79  ? 86  LYS D C   1 
ATOM   6636  O  O   . LYS D 1 86  ? 108.757 114.786 58.661  1.00 47.73  ? 86  LYS D O   1 
ATOM   6637  C  CB  . LYS D 1 86  ? 108.397 112.594 56.039  1.00 45.44  ? 86  LYS D CB  1 
ATOM   6638  C  CG  . LYS D 1 86  ? 108.159 111.132 55.707  1.00 46.89  ? 86  LYS D CG  1 
ATOM   6639  C  CD  . LYS D 1 86  ? 109.075 110.654 54.587  1.00 47.13  ? 86  LYS D CD  1 
ATOM   6640  C  CE  . LYS D 1 86  ? 109.140 109.128 54.541  1.00 52.96  ? 86  LYS D CE  1 
ATOM   6641  N  NZ  . LYS D 1 86  ? 109.123 108.568 53.156  1.00 52.78  ? 86  LYS D NZ  1 
ATOM   6642  N  N   . ALA D 1 87  ? 107.846 115.472 56.711  1.00 47.01  ? 87  ALA D N   1 
ATOM   6643  C  CA  . ALA D 1 87  ? 108.137 116.884 56.951  1.00 52.40  ? 87  ALA D CA  1 
ATOM   6644  C  C   . ALA D 1 87  ? 107.713 117.316 58.347  1.00 49.45  ? 87  ALA D C   1 
ATOM   6645  O  O   . ALA D 1 87  ? 108.416 118.083 59.013  1.00 51.80  ? 87  ALA D O   1 
ATOM   6646  C  CB  . ALA D 1 87  ? 107.437 117.755 55.904  1.00 46.02  ? 87  ALA D CB  1 
ATOM   6647  N  N   . PHE D 1 88  ? 106.569 116.822 58.809  1.00 50.09  ? 88  PHE D N   1 
ATOM   6648  C  CA  . PHE D 1 88  ? 106.019 117.252 60.086  1.00 48.91  ? 88  PHE D CA  1 
ATOM   6649  C  C   . PHE D 1 88  ? 106.720 116.587 61.267  1.00 46.95  ? 88  PHE D C   1 
ATOM   6650  O  O   . PHE D 1 88  ? 106.730 117.151 62.367  1.00 52.05  ? 88  PHE D O   1 
ATOM   6651  C  CB  . PHE D 1 88  ? 104.515 116.959 60.093  1.00 52.12  ? 88  PHE D CB  1 
ATOM   6652  C  CG  . PHE D 1 88  ? 103.843 117.195 61.414  1.00 50.15  ? 88  PHE D CG  1 
ATOM   6653  C  CD1 . PHE D 1 88  ? 103.283 118.425 61.706  1.00 51.86  ? 88  PHE D CD1 1 
ATOM   6654  C  CD2 . PHE D 1 88  ? 103.734 116.171 62.348  1.00 47.59  ? 88  PHE D CD2 1 
ATOM   6655  C  CE1 . PHE D 1 88  ? 102.646 118.635 62.920  1.00 53.00  ? 88  PHE D CE1 1 
ATOM   6656  C  CE2 . PHE D 1 88  ? 103.103 116.374 63.563  1.00 46.90  ? 88  PHE D CE2 1 
ATOM   6657  C  CZ  . PHE D 1 88  ? 102.559 117.606 63.851  1.00 47.84  ? 88  PHE D CZ  1 
ATOM   6658  N  N   . GLY D 1 89  ? 107.297 115.398 61.068  1.00 46.39  ? 89  GLY D N   1 
ATOM   6659  C  CA  . GLY D 1 89  ? 107.998 114.689 62.124  1.00 43.96  ? 89  GLY D CA  1 
ATOM   6660  C  C   . GLY D 1 89  ? 107.588 113.243 62.371  1.00 51.42  ? 89  GLY D C   1 
ATOM   6661  O  O   . GLY D 1 89  ? 108.024 112.637 63.354  1.00 45.75  ? 89  GLY D O   1 
ATOM   6662  N  N   . ILE D 1 90  ? 106.771 112.658 61.498  1.00 50.47  ? 90  ILE D N   1 
ATOM   6663  C  CA  . ILE D 1 90  ? 106.274 111.299 61.700  1.00 47.47  ? 90  ILE D CA  1 
ATOM   6664  C  C   . ILE D 1 90  ? 106.646 110.458 60.487  1.00 47.07  ? 90  ILE D C   1 
ATOM   6665  O  O   . ILE D 1 90  ? 106.300 110.809 59.352  1.00 44.83  ? 90  ILE D O   1 
ATOM   6666  C  CB  . ILE D 1 90  ? 104.754 111.271 61.933  1.00 49.05  ? 90  ILE D CB  1 
ATOM   6667  C  CG1 . ILE D 1 90  ? 104.403 111.977 63.242  1.00 45.69  ? 90  ILE D CG1 1 
ATOM   6668  C  CG2 . ILE D 1 90  ? 104.252 109.831 61.955  1.00 45.64  ? 90  ILE D CG2 1 
ATOM   6669  C  CD1 . ILE D 1 90  ? 102.968 112.437 63.319  1.00 43.50  ? 90  ILE D CD1 1 
ATOM   6670  N  N   . GLU D 1 91  ? 107.342 109.349 60.725  1.00 45.59  ? 91  GLU D N   1 
ATOM   6671  C  CA  . GLU D 1 91  ? 107.689 108.493 59.605  1.00 47.01  ? 91  GLU D CA  1 
ATOM   6672  C  C   . GLU D 1 91  ? 106.570 107.483 59.351  1.00 45.57  ? 91  GLU D C   1 
ATOM   6673  O  O   . GLU D 1 91  ? 105.812 107.149 60.269  1.00 44.45  ? 91  GLU D O   1 
ATOM   6674  C  CB  . GLU D 1 91  ? 109.006 107.754 59.883  1.00 48.79  ? 91  GLU D CB  1 
ATOM   6675  C  CG  . GLU D 1 91  ? 110.242 108.666 60.007  1.00 51.38  ? 91  GLU D CG  1 
ATOM   6676  C  CD  . GLU D 1 91  ? 110.548 109.450 58.733  1.00 53.84  ? 91  GLU D CD  1 
ATOM   6677  O  OE1 . GLU D 1 91  ? 110.865 108.829 57.686  1.00 54.69  ? 91  GLU D OE1 1 
ATOM   6678  O  OE2 . GLU D 1 91  ? 110.470 110.699 58.784  1.00 54.74  ? 91  GLU D OE2 1 
ATOM   6679  N  N   . PRO D 1 92  ? 106.467 106.983 58.112  1.00 43.88  ? 92  PRO D N   1 
ATOM   6680  C  CA  . PRO D 1 92  ? 105.375 106.052 57.769  1.00 43.32  ? 92  PRO D CA  1 
ATOM   6681  C  C   . PRO D 1 92  ? 105.158 104.925 58.767  1.00 46.46  ? 92  PRO D C   1 
ATOM   6682  O  O   . PRO D 1 92  ? 104.011 104.528 58.993  1.00 46.28  ? 92  PRO D O   1 
ATOM   6683  C  CB  . PRO D 1 92  ? 105.814 105.498 56.404  1.00 50.47  ? 92  PRO D CB  1 
ATOM   6684  C  CG  . PRO D 1 92  ? 106.696 106.557 55.822  1.00 50.86  ? 92  PRO D CG  1 
ATOM   6685  C  CD  . PRO D 1 92  ? 107.362 107.248 56.969  1.00 48.47  ? 92  PRO D CD  1 
ATOM   6686  N  N   . ALA D 1 93  ? 106.216 104.393 59.376  1.00 44.66  ? 93  ALA D N   1 
ATOM   6687  C  CA  . ALA D 1 93  ? 106.024 103.273 60.284  1.00 44.23  ? 93  ALA D CA  1 
ATOM   6688  C  C   . ALA D 1 93  ? 105.438 103.691 61.623  1.00 41.73  ? 93  ALA D C   1 
ATOM   6689  O  O   . ALA D 1 93  ? 105.125 102.818 62.438  1.00 46.48  ? 93  ALA D O   1 
ATOM   6690  C  CB  . ALA D 1 93  ? 107.345 102.541 60.518  1.00 45.39  ? 93  ALA D CB  1 
ATOM   6691  N  N   . ASP D 1 94  ? 105.276 104.989 61.873  1.00 37.43  ? 94  ASP D N   1 
ATOM   6692  C  CA  . ASP D 1 94  ? 104.846 105.475 63.178  1.00 43.06  ? 94  ASP D CA  1 
ATOM   6693  C  C   . ASP D 1 94  ? 103.358 105.857 63.201  1.00 41.51  ? 94  ASP D C   1 
ATOM   6694  O  O   . ASP D 1 94  ? 102.930 106.661 64.038  1.00 42.00  ? 94  ASP D O   1 
ATOM   6695  C  CB  . ASP D 1 94  ? 105.742 106.643 63.608  1.00 43.73  ? 94  ASP D CB  1 
ATOM   6696  C  CG  . ASP D 1 94  ? 105.689 106.912 65.105  1.00 51.86  ? 94  ASP D CG  1 
ATOM   6697  O  OD1 . ASP D 1 94  ? 105.624 105.939 65.887  1.00 54.05  ? 94  ASP D OD1 1 
ATOM   6698  O  OD2 . ASP D 1 94  ? 105.740 108.098 65.501  1.00 53.50  ? 94  ASP D OD2 1 
ATOM   6699  N  N   . VAL D 1 95  ? 102.561 105.276 62.310  1.00 40.24  ? 95  VAL D N   1 
ATOM   6700  C  CA  . VAL D 1 95  ? 101.115 105.466 62.279  1.00 36.79  ? 95  VAL D CA  1 
ATOM   6701  C  C   . VAL D 1 95  ? 100.474 104.131 62.626  1.00 35.18  ? 95  VAL D C   1 
ATOM   6702  O  O   . VAL D 1 95  ? 100.716 103.121 61.951  1.00 34.14  ? 95  VAL D O   1 
ATOM   6703  C  CB  . VAL D 1 95  ? 100.638 105.984 60.915  1.00 41.06  ? 95  VAL D CB  1 
ATOM   6704  C  CG1 . VAL D 1 95  ? 99.117  105.979 60.835  1.00 34.49  ? 95  VAL D CG1 1 
ATOM   6705  C  CG2 . VAL D 1 95  ? 101.193 107.393 60.674  1.00 40.17  ? 95  VAL D CG2 1 
ATOM   6706  N  N   . ARG D 1 96  ? 99.691  104.124 63.703  1.00 33.05  ? 96  ARG D N   1 
ATOM   6707  C  CA  . ARG D 1 96  ? 99.063  102.911 64.210  1.00 33.71  ? 96  ARG D CA  1 
ATOM   6708  C  C   . ARG D 1 96  ? 97.720  102.602 63.550  1.00 32.57  ? 96  ARG D C   1 
ATOM   6709  O  O   . ARG D 1 96  ? 97.371  101.426 63.393  1.00 36.83  ? 96  ARG D O   1 
ATOM   6710  C  CB  . ARG D 1 96  ? 98.864  103.030 65.726  1.00 32.52  ? 96  ARG D CB  1 
ATOM   6711  C  CG  . ARG D 1 96  ? 98.333  101.777 66.369  1.00 33.57  ? 96  ARG D CG  1 
ATOM   6712  C  CD  . ARG D 1 96  ? 98.099  101.990 67.847  1.00 30.67  ? 96  ARG D CD  1 
ATOM   6713  N  NE  . ARG D 1 96  ? 97.663  100.759 68.485  1.00 30.14  ? 96  ARG D NE  1 
ATOM   6714  C  CZ  . ARG D 1 96  ? 97.385  100.643 69.777  1.00 36.78  ? 96  ARG D CZ  1 
ATOM   6715  N  NH1 . ARG D 1 96  ? 97.574  101.647 70.620  1.00 40.48  ? 96  ARG D NH1 1 
ATOM   6716  N  NH2 . ARG D 1 96  ? 96.899  99.494  70.233  1.00 30.33  ? 96  ARG D NH2 1 
ATOM   6717  N  N   . TYR D 1 97  ? 96.951  103.618 63.170  1.00 32.31  ? 97  TYR D N   1 
ATOM   6718  C  CA  . TYR D 1 97  ? 95.619  103.402 62.621  1.00 29.35  ? 97  TYR D CA  1 
ATOM   6719  C  C   . TYR D 1 97  ? 95.416  104.309 61.424  1.00 28.88  ? 97  TYR D C   1 
ATOM   6720  O  O   . TYR D 1 97  ? 95.686  105.510 61.507  1.00 31.96  ? 97  TYR D O   1 
ATOM   6721  C  CB  . TYR D 1 97  ? 94.533  103.702 63.655  1.00 29.10  ? 97  TYR D CB  1 
ATOM   6722  C  CG  . TYR D 1 97  ? 94.493  102.766 64.832  1.00 29.67  ? 97  TYR D CG  1 
ATOM   6723  C  CD1 . TYR D 1 97  ? 94.234  101.409 64.660  1.00 31.57  ? 97  TYR D CD1 1 
ATOM   6724  C  CD2 . TYR D 1 97  ? 94.689  103.242 66.127  1.00 29.83  ? 97  TYR D CD2 1 
ATOM   6725  C  CE1 . TYR D 1 97  ? 94.183  100.543 65.748  1.00 30.50  ? 97  TYR D CE1 1 
ATOM   6726  C  CE2 . TYR D 1 97  ? 94.640  102.385 67.216  1.00 29.93  ? 97  TYR D CE2 1 
ATOM   6727  C  CZ  . TYR D 1 97  ? 94.389  101.047 67.018  1.00 28.46  ? 97  TYR D CZ  1 
ATOM   6728  O  OH  . TYR D 1 97  ? 94.337  100.205 68.091  1.00 33.49  ? 97  TYR D OH  1 
ATOM   6729  N  N   . VAL D 1 98  ? 94.925  103.741 60.331  1.00 27.03  ? 98  VAL D N   1 
ATOM   6730  C  CA  . VAL D 1 98  ? 94.348  104.504 59.231  1.00 31.96  ? 98  VAL D CA  1 
ATOM   6731  C  C   . VAL D 1 98  ? 92.830  104.320 59.300  1.00 32.19  ? 98  VAL D C   1 
ATOM   6732  O  O   . VAL D 1 98  ? 92.329  103.197 59.164  1.00 29.55  ? 98  VAL D O   1 
ATOM   6733  C  CB  . VAL D 1 98  ? 94.918  104.058 57.874  1.00 30.03  ? 98  VAL D CB  1 
ATOM   6734  C  CG1 . VAL D 1 98  ? 94.152  104.702 56.726  1.00 30.97  ? 98  VAL D CG1 1 
ATOM   6735  C  CG2 . VAL D 1 98  ? 96.391  104.417 57.790  1.00 32.91  ? 98  VAL D CG2 1 
ATOM   6736  N  N   . LEU D 1 99  ? 92.108  105.409 59.555  1.00 29.23  ? 99  LEU D N   1 
ATOM   6737  C  CA  . LEU D 1 99  ? 90.652  105.400 59.556  1.00 30.85  ? 99  LEU D CA  1 
ATOM   6738  C  C   . LEU D 1 99  ? 90.123  105.890 58.218  1.00 32.48  ? 99  LEU D C   1 
ATOM   6739  O  O   . LEU D 1 99  ? 90.607  106.890 57.678  1.00 28.94  ? 99  LEU D O   1 
ATOM   6740  C  CB  . LEU D 1 99  ? 90.079  106.288 60.660  1.00 26.90  ? 99  LEU D CB  1 
ATOM   6741  C  CG  . LEU D 1 99  ? 90.667  106.187 62.064  1.00 29.63  ? 99  LEU D CG  1 
ATOM   6742  C  CD1 . LEU D 1 99  ? 89.813  107.000 63.024  1.00 27.59  ? 99  LEU D CD1 1 
ATOM   6743  C  CD2 . LEU D 1 99  ? 90.817  104.726 62.500  1.00 23.82  ? 99  LEU D CD2 1 
ATOM   6744  N  N   . HIS D 1 100 ? 89.102  105.208 57.701  1.00 29.18  ? 100 HIS D N   1 
ATOM   6745  C  CA  . HIS D 1 100 ? 88.490  105.615 56.443  1.00 29.09  ? 100 HIS D CA  1 
ATOM   6746  C  C   . HIS D 1 100 ? 87.029  105.972 56.652  1.00 28.84  ? 100 HIS D C   1 
ATOM   6747  O  O   . HIS D 1 100 ? 86.224  105.124 57.061  1.00 27.65  ? 100 HIS D O   1 
ATOM   6748  C  CB  . HIS D 1 100 ? 88.652  104.535 55.377  1.00 27.56  ? 100 HIS D CB  1 
ATOM   6749  C  CG  . HIS D 1 100 ? 90.006  104.544 54.742  1.00 29.61  ? 100 HIS D CG  1 
ATOM   6750  N  ND1 . HIS D 1 100 ? 90.503  105.647 54.080  1.00 28.17  ? 100 HIS D ND1 1 
ATOM   6751  C  CD2 . HIS D 1 100 ? 90.978  103.603 54.693  1.00 28.74  ? 100 HIS D CD2 1 
ATOM   6752  C  CE1 . HIS D 1 100 ? 91.717  105.377 53.636  1.00 33.09  ? 100 HIS D CE1 1 
ATOM   6753  N  NE2 . HIS D 1 100 ? 92.030  104.145 53.999  1.00 32.89  ? 100 HIS D NE2 1 
ATOM   6754  N  N   . SER D 1 101 ? 86.710  107.244 56.394  1.00 30.31  ? 101 SER D N   1 
ATOM   6755  C  CA  . SER D 1 101 ? 85.326  107.683 56.257  1.00 28.68  ? 101 SER D CA  1 
ATOM   6756  C  C   . SER D 1 101 ? 84.599  106.878 55.185  1.00 30.63  ? 101 SER D C   1 
ATOM   6757  O  O   . SER D 1 101 ? 83.488  106.376 55.410  1.00 28.30  ? 101 SER D O   1 
ATOM   6758  C  CB  . SER D 1 101 ? 85.305  109.172 55.922  1.00 28.85  ? 101 SER D CB  1 
ATOM   6759  O  OG  . SER D 1 101 ? 85.782  109.395 54.609  1.00 29.82  ? 101 SER D OG  1 
ATOM   6760  N  N   . HIS D 1 102 ? 85.215  106.760 54.008  1.00 27.77  ? 102 HIS D N   1 
ATOM   6761  C  CA  . HIS D 1 102 ? 84.788  105.886 52.922  1.00 25.88  ? 102 HIS D CA  1 
ATOM   6762  C  C   . HIS D 1 102 ? 85.996  105.674 52.011  1.00 32.17  ? 102 HIS D C   1 
ATOM   6763  O  O   . HIS D 1 102 ? 87.108  106.116 52.320  1.00 33.28  ? 102 HIS D O   1 
ATOM   6764  C  CB  . HIS D 1 102 ? 83.568  106.446 52.176  1.00 27.03  ? 102 HIS D CB  1 
ATOM   6765  C  CG  . HIS D 1 102 ? 83.750  107.825 51.609  1.00 33.07  ? 102 HIS D CG  1 
ATOM   6766  N  ND1 . HIS D 1 102 ? 84.306  108.869 52.323  1.00 32.57  ? 102 HIS D ND1 1 
ATOM   6767  C  CD2 . HIS D 1 102 ? 83.393  108.342 50.405  1.00 28.08  ? 102 HIS D CD2 1 
ATOM   6768  C  CE1 . HIS D 1 102 ? 84.308  109.959 51.573  1.00 31.15  ? 102 HIS D CE1 1 
ATOM   6769  N  NE2 . HIS D 1 102 ? 83.755  109.666 50.408  1.00 31.01  ? 102 HIS D NE2 1 
ATOM   6770  N  N   . LEU D 1 103 ? 85.791  104.993 50.887  1.00 26.67  ? 103 LEU D N   1 
ATOM   6771  C  CA  . LEU D 1 103 ? 86.910  104.592 50.047  1.00 31.78  ? 103 LEU D CA  1 
ATOM   6772  C  C   . LEU D 1 103 ? 86.902  105.303 48.700  1.00 30.84  ? 103 LEU D C   1 
ATOM   6773  O  O   . LEU D 1 103 ? 87.412  104.772 47.712  1.00 28.44  ? 103 LEU D O   1 
ATOM   6774  C  CB  . LEU D 1 103 ? 86.928  103.073 49.871  1.00 26.02  ? 103 LEU D CB  1 
ATOM   6775  C  CG  . LEU D 1 103 ? 87.206  102.367 51.200  1.00 28.21  ? 103 LEU D CG  1 
ATOM   6776  C  CD1 . LEU D 1 103 ? 87.156  100.868 51.046  1.00 25.67  ? 103 LEU D CD1 1 
ATOM   6777  C  CD2 . LEU D 1 103 ? 88.549  102.821 51.779  1.00 22.57  ? 103 LEU D CD2 1 
ATOM   6778  N  N   . HIS D 1 104 ? 86.347  106.510 48.659  1.00 27.59  ? 104 HIS D N   1 
ATOM   6779  C  CA  . HIS D 1 104 ? 86.394  107.302 47.444  1.00 32.29  ? 104 HIS D CA  1 
ATOM   6780  C  C   . HIS D 1 104 ? 87.813  107.799 47.164  1.00 30.78  ? 104 HIS D C   1 
ATOM   6781  O  O   . HIS D 1 104 ? 88.673  107.886 48.050  1.00 29.24  ? 104 HIS D O   1 
ATOM   6782  C  CB  . HIS D 1 104 ? 85.425  108.488 47.528  1.00 30.48  ? 104 HIS D CB  1 
ATOM   6783  C  CG  . HIS D 1 104 ? 84.003  108.116 47.249  1.00 32.84  ? 104 HIS D CG  1 
ATOM   6784  N  ND1 . HIS D 1 104 ? 82.966  109.025 47.302  1.00 28.56  ? 104 HIS D ND1 1 
ATOM   6785  C  CD2 . HIS D 1 104 ? 83.440  106.921 46.946  1.00 31.89  ? 104 HIS D CD2 1 
ATOM   6786  C  CE1 . HIS D 1 104 ? 81.830  108.411 47.029  1.00 35.44  ? 104 HIS D CE1 1 
ATOM   6787  N  NE2 . HIS D 1 104 ? 82.088  107.133 46.812  1.00 35.91  ? 104 HIS D NE2 1 
ATOM   6788  N  N   . LEU D 1 105 ? 88.028  108.139 45.892  1.00 32.12  ? 105 LEU D N   1 
ATOM   6789  C  CA  . LEU D 1 105 ? 89.366  108.372 45.335  1.00 36.03  ? 105 LEU D CA  1 
ATOM   6790  C  C   . LEU D 1 105 ? 90.122  109.493 46.039  1.00 33.56  ? 105 LEU D C   1 
ATOM   6791  O  O   . LEU D 1 105 ? 91.356  109.480 46.059  1.00 34.70  ? 105 LEU D O   1 
ATOM   6792  C  CB  . LEU D 1 105 ? 89.256  108.695 43.836  1.00 33.07  ? 105 LEU D CB  1 
ATOM   6793  C  CG  . LEU D 1 105 ? 88.585  110.004 43.395  1.00 31.87  ? 105 LEU D CG  1 
ATOM   6794  C  CD1 . LEU D 1 105 ? 88.624  110.117 41.872  1.00 38.54  ? 105 LEU D CD1 1 
ATOM   6795  C  CD2 . LEU D 1 105 ? 87.137  110.196 43.892  1.00 30.56  ? 105 LEU D CD2 1 
ATOM   6796  N  N   . ASP D 1 106 ? 89.422  110.479 46.590  1.00 29.98  ? 106 ASP D N   1 
ATOM   6797  C  CA  . ASP D 1 106 ? 90.072  111.532 47.355  1.00 33.65  ? 106 ASP D CA  1 
ATOM   6798  C  C   . ASP D 1 106 ? 90.141  111.219 48.844  1.00 30.63  ? 106 ASP D C   1 
ATOM   6799  O  O   . ASP D 1 106 ? 90.377  112.127 49.646  1.00 34.77  ? 106 ASP D O   1 
ATOM   6800  C  CB  . ASP D 1 106 ? 89.367  112.866 47.117  1.00 33.57  ? 106 ASP D CB  1 
ATOM   6801  C  CG  . ASP D 1 106 ? 87.879  112.802 47.395  1.00 33.91  ? 106 ASP D CG  1 
ATOM   6802  O  OD1 . ASP D 1 106 ? 87.240  111.772 47.102  1.00 33.95  ? 106 ASP D OD1 1 
ATOM   6803  O  OD2 . ASP D 1 106 ? 87.343  113.806 47.881  1.00 34.82  ? 106 ASP D OD2 1 
ATOM   6804  N  N   . HIS D 1 107 ? 89.951  109.951 49.226  1.00 30.70  ? 107 HIS D N   1 
ATOM   6805  C  CA  . HIS D 1 107 ? 90.047  109.543 50.623  1.00 31.22  ? 107 HIS D CA  1 
ATOM   6806  C  C   . HIS D 1 107 ? 90.837  108.252 50.799  1.00 33.33  ? 107 HIS D C   1 
ATOM   6807  O  O   . HIS D 1 107 ? 90.759  107.636 51.870  1.00 29.82  ? 107 HIS D O   1 
ATOM   6808  C  CB  . HIS D 1 107 ? 88.659  109.377 51.231  1.00 28.93  ? 107 HIS D CB  1 
ATOM   6809  C  CG  . HIS D 1 107 ? 87.843  110.627 51.201  1.00 29.67  ? 107 HIS D CG  1 
ATOM   6810  N  ND1 . HIS D 1 107 ? 87.769  111.493 52.271  1.00 31.54  ? 107 HIS D ND1 1 
ATOM   6811  C  CD2 . HIS D 1 107 ? 87.073  111.165 50.225  1.00 30.45  ? 107 HIS D CD2 1 
ATOM   6812  C  CE1 . HIS D 1 107 ? 86.979  112.507 51.960  1.00 30.03  ? 107 HIS D CE1 1 
ATOM   6813  N  NE2 . HIS D 1 107 ? 86.555  112.338 50.720  1.00 34.97  ? 107 HIS D NE2 1 
ATOM   6814  N  N   . THR D 1 108 ? 91.573  107.809 49.779  1.00 33.29  ? 108 THR D N   1 
ATOM   6815  C  CA  . THR D 1 108 ? 92.364  106.588 49.868  1.00 33.63  ? 108 THR D CA  1 
ATOM   6816  C  C   . THR D 1 108 ? 93.854  106.852 49.656  1.00 35.64  ? 108 THR D C   1 
ATOM   6817  O  O   . THR D 1 108 ? 94.607  105.918 49.365  1.00 35.04  ? 108 THR D O   1 
ATOM   6818  C  CB  . THR D 1 108 ? 91.857  105.537 48.870  1.00 36.11  ? 108 THR D CB  1 
ATOM   6819  O  OG1 . THR D 1 108 ? 91.674  106.116 47.566  1.00 32.05  ? 108 THR D OG1 1 
ATOM   6820  C  CG2 . THR D 1 108 ? 90.550  104.914 49.357  1.00 33.90  ? 108 THR D CG2 1 
ATOM   6821  N  N   . GLY D 1 109 ? 94.298  108.107 49.798  1.00 35.83  ? 109 GLY D N   1 
ATOM   6822  C  CA  . GLY D 1 109 ? 95.722  108.389 49.692  1.00 38.09  ? 109 GLY D CA  1 
ATOM   6823  C  C   . GLY D 1 109 ? 96.554  107.721 50.775  1.00 36.84  ? 109 GLY D C   1 
ATOM   6824  O  O   . GLY D 1 109 ? 97.740  107.452 50.573  1.00 36.87  ? 109 GLY D O   1 
ATOM   6825  N  N   . ALA D 1 110 ? 95.951  107.434 51.928  1.00 33.77  ? 110 ALA D N   1 
ATOM   6826  C  CA  . ALA D 1 110 ? 96.675  106.824 53.034  1.00 35.77  ? 110 ALA D CA  1 
ATOM   6827  C  C   . ALA D 1 110 ? 96.767  105.308 52.946  1.00 38.62  ? 110 ALA D C   1 
ATOM   6828  O  O   . ALA D 1 110 ? 97.647  104.728 53.593  1.00 40.49  ? 110 ALA D O   1 
ATOM   6829  C  CB  . ALA D 1 110 ? 96.020  107.196 54.371  1.00 33.33  ? 110 ALA D CB  1 
ATOM   6830  N  N   . THR D 1 111 ? 95.898  104.659 52.164  1.00 33.47  ? 111 THR D N   1 
ATOM   6831  C  CA  . THR D 1 111 ? 95.725  103.207 52.248  1.00 37.03  ? 111 THR D CA  1 
ATOM   6832  C  C   . THR D 1 111 ? 96.994  102.459 51.853  1.00 37.35  ? 111 THR D C   1 
ATOM   6833  O  O   . THR D 1 111 ? 97.488  102.601 50.730  1.00 39.21  ? 111 THR D O   1 
ATOM   6834  C  CB  . THR D 1 111 ? 94.567  102.756 51.351  1.00 36.96  ? 111 THR D CB  1 
ATOM   6835  O  OG1 . THR D 1 111 ? 93.444  103.633 51.513  1.00 31.86  ? 111 THR D OG1 1 
ATOM   6836  C  CG2 . THR D 1 111 ? 94.179  101.310 51.677  1.00 32.02  ? 111 THR D CG2 1 
ATOM   6837  N  N   . GLY D 1 112 ? 97.505  101.638 52.766  1.00 35.03  ? 112 GLY D N   1 
ATOM   6838  C  CA  . GLY D 1 112 ? 98.654  100.810 52.467  1.00 42.27  ? 112 GLY D CA  1 
ATOM   6839  C  C   . GLY D 1 112 ? 99.976  101.544 52.371  1.00 45.22  ? 112 GLY D C   1 
ATOM   6840  O  O   . GLY D 1 112 ? 100.989 100.916 52.031  1.00 48.41  ? 112 GLY D O   1 
ATOM   6841  N  N   . ARG D 1 113 ? 99.998  102.848 52.648  1.00 42.41  ? 113 ARG D N   1 
ATOM   6842  C  CA  . ARG D 1 113 ? 101.224 103.631 52.695  1.00 42.41  ? 113 ARG D CA  1 
ATOM   6843  C  C   . ARG D 1 113 ? 101.873 103.621 54.068  1.00 42.70  ? 113 ARG D C   1 
ATOM   6844  O  O   . ARG D 1 113 ? 102.978 104.151 54.221  1.00 46.18  ? 113 ARG D O   1 
ATOM   6845  C  CB  . ARG D 1 113 ? 100.942 105.084 52.308  1.00 38.19  ? 113 ARG D CB  1 
ATOM   6846  C  CG  . ARG D 1 113 ? 100.995 105.349 50.836  1.00 36.72  ? 113 ARG D CG  1 
ATOM   6847  C  CD  . ARG D 1 113 ? 99.643  105.111 50.245  1.00 41.71  ? 113 ARG D CD  1 
ATOM   6848  N  NE  . ARG D 1 113 ? 99.556  105.550 48.863  1.00 41.72  ? 113 ARG D NE  1 
ATOM   6849  C  CZ  . ARG D 1 113 ? 98.477  105.403 48.109  1.00 42.60  ? 113 ARG D CZ  1 
ATOM   6850  N  NH1 . ARG D 1 113 ? 97.394  104.786 48.561  1.00 40.05  ? 113 ARG D NH1 1 
ATOM   6851  N  NH2 . ARG D 1 113 ? 98.478  105.896 46.875  1.00 45.51  ? 113 ARG D NH2 1 
ATOM   6852  N  N   . PHE D 1 114 ? 101.206 103.069 55.069  1.00 39.24  ? 114 PHE D N   1 
ATOM   6853  C  CA  . PHE D 1 114 ? 101.706 103.074 56.441  1.00 36.92  ? 114 PHE D CA  1 
ATOM   6854  C  C   . PHE D 1 114 ? 101.867 101.631 56.875  1.00 41.21  ? 114 PHE D C   1 
ATOM   6855  O  O   . PHE D 1 114 ? 100.859 100.930 57.094  1.00 36.37  ? 114 PHE D O   1 
ATOM   6856  C  CB  . PHE D 1 114 ? 100.757 103.853 57.351  1.00 34.45  ? 114 PHE D CB  1 
ATOM   6857  C  CG  . PHE D 1 114 ? 100.649 105.297 56.972  1.00 38.96  ? 114 PHE D CG  1 
ATOM   6858  C  CD1 . PHE D 1 114 ? 101.633 106.197 57.350  1.00 39.93  ? 114 PHE D CD1 1 
ATOM   6859  C  CD2 . PHE D 1 114 ? 99.610  105.744 56.168  1.00 39.70  ? 114 PHE D CD2 1 
ATOM   6860  C  CE1 . PHE D 1 114 ? 101.564 107.531 56.971  1.00 42.10  ? 114 PHE D CE1 1 
ATOM   6861  C  CE2 . PHE D 1 114 ? 99.528  107.073 55.782  1.00 39.97  ? 114 PHE D CE2 1 
ATOM   6862  C  CZ  . PHE D 1 114 ? 100.509 107.973 56.191  1.00 43.09  ? 114 PHE D CZ  1 
ATOM   6863  N  N   . PRO D 1 115 ? 103.107 101.151 56.994  1.00 45.74  ? 115 PRO D N   1 
ATOM   6864  C  CA  . PRO D 1 115 ? 103.346 99.700  56.954  1.00 39.05  ? 115 PRO D CA  1 
ATOM   6865  C  C   . PRO D 1 115 ? 102.838 98.955  58.172  1.00 37.77  ? 115 PRO D C   1 
ATOM   6866  O  O   . PRO D 1 115 ? 102.639 97.738  58.090  1.00 41.89  ? 115 PRO D O   1 
ATOM   6867  C  CB  . PRO D 1 115 ? 104.878 99.585  56.843  1.00 40.34  ? 115 PRO D CB  1 
ATOM   6868  C  CG  . PRO D 1 115 ? 105.435 100.915 57.193  1.00 39.28  ? 115 PRO D CG  1 
ATOM   6869  C  CD  . PRO D 1 115 ? 104.347 101.945 57.057  1.00 45.55  ? 115 PRO D CD  1 
ATOM   6870  N  N   . ASN D 1 116 ? 102.631 99.618  59.301  1.00 36.78  ? 116 ASN D N   1 
ATOM   6871  C  CA  . ASN D 1 116 ? 102.143 98.917  60.484  1.00 39.32  ? 116 ASN D CA  1 
ATOM   6872  C  C   . ASN D 1 116 ? 100.714 99.308  60.870  1.00 33.44  ? 116 ASN D C   1 
ATOM   6873  O  O   . ASN D 1 116 ? 100.229 98.871  61.915  1.00 33.58  ? 116 ASN D O   1 
ATOM   6874  C  CB  . ASN D 1 116 ? 103.078 99.150  61.678  1.00 35.09  ? 116 ASN D CB  1 
ATOM   6875  C  CG  . ASN D 1 116 ? 104.538 98.800  61.383  1.00 39.20  ? 116 ASN D CG  1 
ATOM   6876  O  OD1 . ASN D 1 116 ? 104.845 97.804  60.730  1.00 45.72  ? 116 ASN D OD1 1 
ATOM   6877  N  ND2 . ASN D 1 116 ? 105.440 99.634  61.868  1.00 39.19  ? 116 ASN D ND2 1 
ATOM   6878  N  N   . ALA D 1 117 ? 100.059 100.121 60.063  1.00 33.97  ? 117 ALA D N   1 
ATOM   6879  C  CA  . ALA D 1 117 ? 98.739  100.648 60.474  1.00 38.33  ? 117 ALA D CA  1 
ATOM   6880  C  C   . ALA D 1 117 ? 97.588  99.669  60.235  1.00 34.95  ? 117 ALA D C   1 
ATOM   6881  O  O   . ALA D 1 117 ? 97.558  99.016  59.191  1.00 31.90  ? 117 ALA D O   1 
ATOM   6882  C  CB  . ALA D 1 117 ? 98.467  101.945 59.768  1.00 34.26  ? 117 ALA D CB  1 
ATOM   6883  N  N   . ILE D 1 118 ? 96.691  99.584  61.208  1.00 36.24  ? 118 ILE D N   1 
ATOM   6884  C  CA  . ILE D 1 118 ? 95.455  98.787  60.997  1.00 35.81  ? 118 ILE D CA  1 
ATOM   6885  C  C   . ILE D 1 118 ? 94.454  99.726  60.325  1.00 31.47  ? 118 ILE D C   1 
ATOM   6886  O  O   . ILE D 1 118 ? 94.277  100.843 60.816  1.00 33.49  ? 118 ILE D O   1 
ATOM   6887  C  CB  . ILE D 1 118 ? 94.937  98.200  62.321  1.00 37.32  ? 118 ILE D CB  1 
ATOM   6888  C  CG1 . ILE D 1 118 ? 95.776  97.001  62.760  1.00 36.00  ? 118 ILE D CG1 1 
ATOM   6889  C  CG2 . ILE D 1 118 ? 93.462  97.848  62.222  1.00 33.34  ? 118 ILE D CG2 1 
ATOM   6890  C  CD1 . ILE D 1 118 ? 96.317  97.117  64.156  1.00 42.24  ? 118 ILE D CD1 1 
ATOM   6891  N  N   . HIS D 1 119 ? 93.856  99.284  59.229  1.00 29.74  ? 119 HIS D N   1 
ATOM   6892  C  CA  . HIS D 1 119 ? 92.911  100.127 58.467  1.00 28.27  ? 119 HIS D CA  1 
ATOM   6893  C  C   . HIS D 1 119 ? 91.484  99.820  58.929  1.00 30.35  ? 119 HIS D C   1 
ATOM   6894  O  O   . HIS D 1 119 ? 91.021  98.685  58.770  1.00 30.68  ? 119 HIS D O   1 
ATOM   6895  C  CB  . HIS D 1 119 ? 93.163  99.935  56.972  1.00 30.47  ? 119 HIS D CB  1 
ATOM   6896  C  CG  . HIS D 1 119 ? 94.511  100.355 56.500  1.00 32.00  ? 119 HIS D CG  1 
ATOM   6897  N  ND1 . HIS D 1 119 ? 95.690  99.823  56.968  1.00 34.14  ? 119 HIS D ND1 1 
ATOM   6898  C  CD2 . HIS D 1 119 ? 94.852  101.250 55.573  1.00 34.01  ? 119 HIS D CD2 1 
ATOM   6899  C  CE1 . HIS D 1 119 ? 96.703  100.399 56.345  1.00 36.51  ? 119 HIS D CE1 1 
ATOM   6900  N  NE2 . HIS D 1 119 ? 96.215  101.271 55.497  1.00 34.47  ? 119 HIS D NE2 1 
ATOM   6901  N  N   . ILE D 1 120 ? 90.822  100.816 59.507  1.00 25.19  ? 120 ILE D N   1 
ATOM   6902  C  CA  . ILE D 1 120 ? 89.475  100.628 60.031  1.00 25.59  ? 120 ILE D CA  1 
ATOM   6903  C  C   . ILE D 1 120 ? 88.491  101.319 59.097  1.00 26.85  ? 120 ILE D C   1 
ATOM   6904  O  O   . ILE D 1 120 ? 88.618  102.524 58.829  1.00 27.32  ? 120 ILE D O   1 
ATOM   6905  C  CB  . ILE D 1 120 ? 89.334  101.158 61.465  1.00 27.51  ? 120 ILE D CB  1 
ATOM   6906  C  CG1 . ILE D 1 120 ? 90.488  100.658 62.336  1.00 27.21  ? 120 ILE D CG1 1 
ATOM   6907  C  CG2 . ILE D 1 120 ? 87.983  100.746 62.061  1.00 24.78  ? 120 ILE D CG2 1 
ATOM   6908  C  CD1 . ILE D 1 120 ? 90.359  101.040 63.777  1.00 24.42  ? 120 ILE D CD1 1 
ATOM   6909  N  N   . VAL D 1 121 ? 87.506  100.553 58.620  1.00 25.07  ? 121 VAL D N   1 
ATOM   6910  C  CA  . VAL D 1 121 ? 86.441  101.069 57.760  1.00 24.13  ? 121 VAL D CA  1 
ATOM   6911  C  C   . VAL D 1 121 ? 85.234  100.146 57.889  1.00 22.46  ? 121 VAL D C   1 
ATOM   6912  O  O   . VAL D 1 121 ? 85.352  98.995  58.319  1.00 24.20  ? 121 VAL D O   1 
ATOM   6913  C  CB  . VAL D 1 121 ? 86.911  101.167 56.285  1.00 27.17  ? 121 VAL D CB  1 
ATOM   6914  C  CG1 . VAL D 1 121 ? 86.903  99.778  55.633  1.00 23.28  ? 121 VAL D CG1 1 
ATOM   6915  C  CG2 . VAL D 1 121 ? 86.051  102.159 55.500  1.00 25.80  ? 121 VAL D CG2 1 
ATOM   6916  N  N   . ARG D 1 122 ? 84.063  100.643 57.497  1.00 21.88  ? 122 ARG D N   1 
ATOM   6917  C  CA  . ARG D 1 122 ? 82.865  99.808  57.500  1.00 23.07  ? 122 ARG D CA  1 
ATOM   6918  C  C   . ARG D 1 122 ? 83.014  98.671  56.501  1.00 24.33  ? 122 ARG D C   1 
ATOM   6919  O  O   . ARG D 1 122 ? 83.414  98.892  55.349  1.00 26.57  ? 122 ARG D O   1 
ATOM   6920  C  CB  . ARG D 1 122 ? 81.633  100.647 57.160  1.00 24.97  ? 122 ARG D CB  1 
ATOM   6921  C  CG  . ARG D 1 122 ? 81.053  101.359 58.375  1.00 27.80  ? 122 ARG D CG  1 
ATOM   6922  C  CD  . ARG D 1 122 ? 79.600  101.754 58.157  1.00 24.99  ? 122 ARG D CD  1 
ATOM   6923  N  NE  . ARG D 1 122 ? 78.702  100.620 58.262  1.00 23.11  ? 122 ARG D NE  1 
ATOM   6924  C  CZ  . ARG D 1 122 ? 77.381  100.719 58.231  1.00 28.12  ? 122 ARG D CZ  1 
ATOM   6925  N  NH1 . ARG D 1 122 ? 76.781  101.885 58.059  1.00 26.03  ? 122 ARG D NH1 1 
ATOM   6926  N  NH2 . ARG D 1 122 ? 76.644  99.625  58.391  1.00 28.94  ? 122 ARG D NH2 1 
ATOM   6927  N  N   . ARG D 1 123 ? 82.714  97.453  56.954  1.00 20.22  ? 123 ARG D N   1 
ATOM   6928  C  CA  . ARG D 1 123 ? 82.659  96.314  56.043  1.00 27.45  ? 123 ARG D CA  1 
ATOM   6929  C  C   . ARG D 1 123 ? 81.917  96.632  54.746  1.00 24.79  ? 123 ARG D C   1 
ATOM   6930  O  O   . ARG D 1 123 ? 82.387  96.299  53.651  1.00 27.98  ? 123 ARG D O   1 
ATOM   6931  C  CB  . ARG D 1 123 ? 82.001  95.102  56.709  1.00 22.04  ? 123 ARG D CB  1 
ATOM   6932  C  CG  . ARG D 1 123 ? 81.802  93.961  55.685  1.00 24.83  ? 123 ARG D CG  1 
ATOM   6933  C  CD  . ARG D 1 123 ? 81.432  92.635  56.343  1.00 22.81  ? 123 ARG D CD  1 
ATOM   6934  N  NE  . ARG D 1 123 ? 82.591  92.048  57.011  1.00 29.14  ? 123 ARG D NE  1 
ATOM   6935  C  CZ  . ARG D 1 123 ? 83.603  91.467  56.377  1.00 29.79  ? 123 ARG D CZ  1 
ATOM   6936  N  NH1 . ARG D 1 123 ? 83.659  91.414  55.050  1.00 30.09  ? 123 ARG D NH1 1 
ATOM   6937  N  NH2 . ARG D 1 123 ? 84.573  90.910  57.085  1.00 31.03  ? 123 ARG D NH2 1 
ATOM   6938  N  N   . CYS D 1 124 ? 80.764  97.286  54.840  1.00 21.49  ? 124 CYS D N   1 
ATOM   6939  C  CA  . CYS D 1 124 ? 79.958  97.416  53.641  1.00 25.41  ? 124 CYS D CA  1 
ATOM   6940  C  C   . CYS D 1 124 ? 80.532  98.444  52.684  1.00 26.35  ? 124 CYS D C   1 
ATOM   6941  O  O   . CYS D 1 124 ? 80.271  98.349  51.480  1.00 25.92  ? 124 CYS D O   1 
ATOM   6942  C  CB  . CYS D 1 124 ? 78.498  97.730  53.996  1.00 20.80  ? 124 CYS D CB  1 
ATOM   6943  S  SG  . CYS D 1 124 ? 78.135  99.367  54.619  1.00 32.85  ? 124 CYS D SG  1 
ATOM   6944  N  N   . GLU D 1 125 ? 81.343  99.384  53.183  1.00 24.61  ? 125 GLU D N   1 
ATOM   6945  C  CA  . GLU D 1 125 ? 82.117  100.238 52.287  1.00 26.67  ? 125 GLU D CA  1 
ATOM   6946  C  C   . GLU D 1 125 ? 83.186  99.442  51.550  1.00 25.52  ? 125 GLU D C   1 
ATOM   6947  O  O   . GLU D 1 125 ? 83.339  99.575  50.334  1.00 29.85  ? 125 GLU D O   1 
ATOM   6948  C  CB  . GLU D 1 125 ? 82.756  101.395 53.061  1.00 22.95  ? 125 GLU D CB  1 
ATOM   6949  C  CG  . GLU D 1 125 ? 83.439  102.385 52.159  1.00 24.71  ? 125 GLU D CG  1 
ATOM   6950  C  CD  . GLU D 1 125 ? 82.478  103.101 51.207  1.00 30.39  ? 125 GLU D CD  1 
ATOM   6951  O  OE1 . GLU D 1 125 ? 81.231  102.987 51.371  1.00 24.83  ? 125 GLU D OE1 1 
ATOM   6952  O  OE2 . GLU D 1 125 ? 82.979  103.799 50.298  1.00 27.32  ? 125 GLU D OE2 1 
ATOM   6953  N  N   . TYR D 1 126 ? 83.950  98.626  52.277  1.00 25.36  ? 126 TYR D N   1 
ATOM   6954  C  CA  . TYR D 1 126 ? 84.971  97.804  51.637  1.00 26.09  ? 126 TYR D CA  1 
ATOM   6955  C  C   . TYR D 1 126 ? 84.362  96.884  50.587  1.00 28.55  ? 126 TYR D C   1 
ATOM   6956  O  O   . TYR D 1 126 ? 84.899  96.750  49.481  1.00 30.99  ? 126 TYR D O   1 
ATOM   6957  C  CB  . TYR D 1 126 ? 85.718  96.987  52.694  1.00 24.99  ? 126 TYR D CB  1 
ATOM   6958  C  CG  . TYR D 1 126 ? 86.778  96.063  52.151  1.00 30.45  ? 126 TYR D CG  1 
ATOM   6959  C  CD1 . TYR D 1 126 ? 88.053  96.529  51.860  1.00 32.43  ? 126 TYR D CD1 1 
ATOM   6960  C  CD2 . TYR D 1 126 ? 86.504  94.715  51.926  1.00 32.52  ? 126 TYR D CD2 1 
ATOM   6961  C  CE1 . TYR D 1 126 ? 89.030  95.677  51.365  1.00 33.67  ? 126 TYR D CE1 1 
ATOM   6962  C  CE2 . TYR D 1 126 ? 87.463  93.863  51.438  1.00 37.38  ? 126 TYR D CE2 1 
ATOM   6963  C  CZ  . TYR D 1 126 ? 88.723  94.348  51.153  1.00 40.43  ? 126 TYR D CZ  1 
ATOM   6964  O  OH  . TYR D 1 126 ? 89.674  93.490  50.660  1.00 47.18  ? 126 TYR D OH  1 
ATOM   6965  N  N   . GLU D 1 127 ? 83.241  96.235  50.914  1.00 26.30  ? 127 GLU D N   1 
ATOM   6966  C  CA  . GLU D 1 127 ? 82.646  95.303  49.965  1.00 27.03  ? 127 GLU D CA  1 
ATOM   6967  C  C   . GLU D 1 127 ? 82.120  96.026  48.737  1.00 28.27  ? 127 GLU D C   1 
ATOM   6968  O  O   . GLU D 1 127 ? 82.300  95.540  47.618  1.00 26.83  ? 127 GLU D O   1 
ATOM   6969  C  CB  . GLU D 1 127 ? 81.545  94.486  50.635  1.00 23.24  ? 127 GLU D CB  1 
ATOM   6970  C  CG  . GLU D 1 127 ? 82.132  93.540  51.641  1.00 24.58  ? 127 GLU D CG  1 
ATOM   6971  C  CD  . GLU D 1 127 ? 81.098  92.766  52.403  1.00 23.81  ? 127 GLU D CD  1 
ATOM   6972  O  OE1 . GLU D 1 127 ? 79.910  93.133  52.348  1.00 28.91  ? 127 GLU D OE1 1 
ATOM   6973  O  OE2 . GLU D 1 127 ? 81.487  91.783  53.048  1.00 26.69  ? 127 GLU D OE2 1 
ATOM   6974  N  N   . TYR D 1 128 ? 81.490  97.195  48.923  1.00 25.39  ? 128 TYR D N   1 
ATOM   6975  C  CA  . TYR D 1 128 ? 80.980  97.947  47.777  1.00 26.77  ? 128 TYR D CA  1 
ATOM   6976  C  C   . TYR D 1 128 ? 82.118  98.440  46.891  1.00 29.12  ? 128 TYR D C   1 
ATOM   6977  O  O   . TYR D 1 128 ? 81.998  98.432  45.663  1.00 26.54  ? 128 TYR D O   1 
ATOM   6978  C  CB  . TYR D 1 128 ? 80.136  99.131  48.247  1.00 24.54  ? 128 TYR D CB  1 
ATOM   6979  C  CG  . TYR D 1 128 ? 79.442  99.843  47.116  1.00 26.93  ? 128 TYR D CG  1 
ATOM   6980  C  CD1 . TYR D 1 128 ? 78.282  99.307  46.535  1.00 27.66  ? 128 TYR D CD1 1 
ATOM   6981  C  CD2 . TYR D 1 128 ? 79.938  101.046 46.610  1.00 26.56  ? 128 TYR D CD2 1 
ATOM   6982  C  CE1 . TYR D 1 128 ? 77.638  99.952  45.484  1.00 23.45  ? 128 TYR D CE1 1 
ATOM   6983  C  CE2 . TYR D 1 128 ? 79.302  101.701 45.553  1.00 24.09  ? 128 TYR D CE2 1 
ATOM   6984  C  CZ  . TYR D 1 128 ? 78.147  101.145 45.002  1.00 27.83  ? 128 TYR D CZ  1 
ATOM   6985  O  OH  . TYR D 1 128 ? 77.502  101.782 43.964  1.00 28.53  ? 128 TYR D OH  1 
ATOM   6986  N  N   . ALA D 1 129 ? 83.226  98.874  47.508  1.00 27.06  ? 129 ALA D N   1 
ATOM   6987  C  CA  . ALA D 1 129 ? 84.376  99.359  46.753  1.00 26.51  ? 129 ALA D CA  1 
ATOM   6988  C  C   . ALA D 1 129 ? 84.943  98.269  45.852  1.00 27.54  ? 129 ALA D C   1 
ATOM   6989  O  O   . ALA D 1 129 ? 85.392  98.553  44.742  1.00 34.60  ? 129 ALA D O   1 
ATOM   6990  C  CB  . ALA D 1 129 ? 85.452  99.866  47.711  1.00 26.22  ? 129 ALA D CB  1 
ATOM   6991  N  N   . MET D 1 130 ? 84.928  97.012  46.316  1.00 28.79  ? 130 MET D N   1 
ATOM   6992  C  CA  . MET D 1 130 ? 85.380  95.898  45.482  1.00 31.91  ? 130 MET D CA  1 
ATOM   6993  C  C   . MET D 1 130 ? 84.405  95.596  44.349  1.00 33.09  ? 130 MET D C   1 
ATOM   6994  O  O   . MET D 1 130 ? 84.797  95.003  43.341  1.00 35.23  ? 130 MET D O   1 
ATOM   6995  C  CB  . MET D 1 130 ? 85.569  94.647  46.339  1.00 28.61  ? 130 MET D CB  1 
ATOM   6996  C  CG  . MET D 1 130 ? 86.712  94.750  47.333  1.00 34.76  ? 130 MET D CG  1 
ATOM   6997  S  SD  . MET D 1 130 ? 88.312  95.087  46.581  1.00 41.43  ? 130 MET D SD  1 
ATOM   6998  C  CE  . MET D 1 130 ? 89.023  93.445  46.735  1.00 46.03  ? 130 MET D CE  1 
ATOM   6999  N  N   . ALA D 1 131 ? 83.133  95.958  44.495  1.00 32.66  ? 131 ALA D N   1 
ATOM   7000  C  CA  . ALA D 1 131 ? 82.108  95.597  43.515  1.00 32.95  ? 131 ALA D CA  1 
ATOM   7001  C  C   . ALA D 1 131 ? 81.101  96.728  43.373  1.00 29.74  ? 131 ALA D C   1 
ATOM   7002  O  O   . ALA D 1 131 ? 79.913  96.562  43.666  1.00 30.62  ? 131 ALA D O   1 
ATOM   7003  C  CB  . ALA D 1 131 ? 81.420  94.292  43.918  1.00 29.52  ? 131 ALA D CB  1 
ATOM   7004  N  N   . PRO D 1 132 ? 81.536  97.887  42.884  1.00 32.53  ? 132 PRO D N   1 
ATOM   7005  C  CA  . PRO D 1 132 ? 80.627  99.032  42.761  1.00 26.75  ? 132 PRO D CA  1 
ATOM   7006  C  C   . PRO D 1 132 ? 79.713  98.893  41.551  1.00 30.03  ? 132 PRO D C   1 
ATOM   7007  O  O   . PRO D 1 132 ? 79.855  97.989  40.723  1.00 31.08  ? 132 PRO D O   1 
ATOM   7008  C  CB  . PRO D 1 132 ? 81.579  100.216 42.585  1.00 28.38  ? 132 PRO D CB  1 
ATOM   7009  C  CG  . PRO D 1 132 ? 82.724  99.629  41.869  1.00 28.72  ? 132 PRO D CG  1 
ATOM   7010  C  CD  . PRO D 1 132 ? 82.883  98.208  42.375  1.00 27.09  ? 132 PRO D CD  1 
ATOM   7011  N  N   . ASP D 1 133 ? 78.755  99.814  41.470  1.00 28.43  ? 133 ASP D N   1 
ATOM   7012  C  CA  . ASP D 1 133 ? 77.910  99.952  40.292  1.00 30.95  ? 133 ASP D CA  1 
ATOM   7013  C  C   . ASP D 1 133 ? 78.590  100.878 39.283  1.00 30.30  ? 133 ASP D C   1 
ATOM   7014  O  O   . ASP D 1 133 ? 79.571  101.560 39.593  1.00 31.02  ? 133 ASP D O   1 
ATOM   7015  C  CB  . ASP D 1 133 ? 76.519  100.491 40.672  1.00 23.46  ? 133 ASP D CB  1 
ATOM   7016  C  CG  . ASP D 1 133 ? 75.788  99.595  41.672  1.00 27.91  ? 133 ASP D CG  1 
ATOM   7017  O  OD1 . ASP D 1 133 ? 75.206  98.576  41.246  1.00 26.22  ? 133 ASP D OD1 1 
ATOM   7018  O  OD2 . ASP D 1 133 ? 75.779  99.913  42.885  1.00 28.14  ? 133 ASP D OD2 1 
ATOM   7019  N  N   . TRP D 1 134 ? 78.043  100.913 38.062  1.00 27.69  ? 134 TRP D N   1 
ATOM   7020  C  CA  . TRP D 1 134 ? 78.694  101.659 36.987  1.00 31.22  ? 134 TRP D CA  1 
ATOM   7021  C  C   . TRP D 1 134 ? 78.834  103.139 37.322  1.00 34.67  ? 134 TRP D C   1 
ATOM   7022  O  O   . TRP D 1 134 ? 79.883  103.741 37.061  1.00 34.55  ? 134 TRP D O   1 
ATOM   7023  C  CB  . TRP D 1 134 ? 77.937  101.468 35.670  1.00 30.41  ? 134 TRP D CB  1 
ATOM   7024  C  CG  . TRP D 1 134 ? 76.572  102.050 35.599  1.00 29.09  ? 134 TRP D CG  1 
ATOM   7025  C  CD1 . TRP D 1 134 ? 75.398  101.381 35.770  1.00 27.60  ? 134 TRP D CD1 1 
ATOM   7026  C  CD2 . TRP D 1 134 ? 76.214  103.406 35.275  1.00 32.38  ? 134 TRP D CD2 1 
ATOM   7027  N  NE1 . TRP D 1 134 ? 74.329  102.234 35.602  1.00 27.09  ? 134 TRP D NE1 1 
ATOM   7028  C  CE2 . TRP D 1 134 ? 74.800  103.484 35.302  1.00 29.41  ? 134 TRP D CE2 1 
ATOM   7029  C  CE3 . TRP D 1 134 ? 76.947  104.563 34.989  1.00 30.74  ? 134 TRP D CE3 1 
ATOM   7030  C  CZ2 . TRP D 1 134 ? 74.110  104.669 35.052  1.00 29.86  ? 134 TRP D CZ2 1 
ATOM   7031  C  CZ3 . TRP D 1 134 ? 76.256  105.749 34.745  1.00 31.51  ? 134 TRP D CZ3 1 
ATOM   7032  C  CH2 . TRP D 1 134 ? 74.852  105.788 34.771  1.00 35.15  ? 134 TRP D CH2 1 
ATOM   7033  N  N   . PHE D 1 135 ? 77.800  103.740 37.930  1.00 30.64  ? 135 PHE D N   1 
ATOM   7034  C  CA  . PHE D 1 135 ? 77.845  105.170 38.211  1.00 32.51  ? 135 PHE D CA  1 
ATOM   7035  C  C   . PHE D 1 135 ? 78.914  105.538 39.233  1.00 30.91  ? 135 PHE D C   1 
ATOM   7036  O  O   . PHE D 1 135 ? 79.285  106.713 39.321  1.00 31.13  ? 135 PHE D O   1 
ATOM   7037  C  CB  . PHE D 1 135 ? 76.465  105.667 38.692  1.00 31.82  ? 135 PHE D CB  1 
ATOM   7038  C  CG  . PHE D 1 135 ? 76.189  105.401 40.149  1.00 28.22  ? 135 PHE D CG  1 
ATOM   7039  C  CD1 . PHE D 1 135 ? 75.642  104.193 40.553  1.00 29.62  ? 135 PHE D CD1 1 
ATOM   7040  C  CD2 . PHE D 1 135 ? 76.468  106.354 41.111  1.00 30.35  ? 135 PHE D CD2 1 
ATOM   7041  C  CE1 . PHE D 1 135 ? 75.385  103.939 41.894  1.00 31.98  ? 135 PHE D CE1 1 
ATOM   7042  C  CE2 . PHE D 1 135 ? 76.230  106.105 42.456  1.00 28.51  ? 135 PHE D CE2 1 
ATOM   7043  C  CZ  . PHE D 1 135 ? 75.676  104.901 42.850  1.00 28.49  ? 135 PHE D CZ  1 
ATOM   7044  N  N   . SER D 1 136 ? 79.401  104.585 40.022  1.00 30.43  ? 136 SER D N   1 
ATOM   7045  C  CA  . SER D 1 136 ? 80.385  104.906 41.043  1.00 32.28  ? 136 SER D CA  1 
ATOM   7046  C  C   . SER D 1 136 ? 81.701  104.169 40.853  1.00 31.56  ? 136 SER D C   1 
ATOM   7047  O  O   . SER D 1 136 ? 82.621  104.372 41.650  1.00 35.02  ? 136 SER D O   1 
ATOM   7048  C  CB  . SER D 1 136 ? 79.838  104.597 42.445  1.00 27.39  ? 136 SER D CB  1 
ATOM   7049  O  OG  . SER D 1 136 ? 79.518  103.226 42.553  1.00 35.03  ? 136 SER D OG  1 
ATOM   7050  N  N   . ALA D 1 137 ? 81.819  103.319 39.834  1.00 30.74  ? 137 ALA D N   1 
ATOM   7051  C  CA  . ALA D 1 137 ? 83.028  102.513 39.680  1.00 30.88  ? 137 ALA D CA  1 
ATOM   7052  C  C   . ALA D 1 137 ? 84.275  103.388 39.566  1.00 34.71  ? 137 ALA D C   1 
ATOM   7053  O  O   . ALA D 1 137 ? 85.322  103.058 40.141  1.00 35.98  ? 137 ALA D O   1 
ATOM   7054  C  CB  . ALA D 1 137 ? 82.891  101.599 38.465  1.00 30.30  ? 137 ALA D CB  1 
ATOM   7055  N  N   . GLY D 1 138 ? 84.171  104.521 38.858  1.00 33.54  ? 138 GLY D N   1 
ATOM   7056  C  CA  . GLY D 1 138 ? 85.296  105.422 38.652  1.00 37.04  ? 138 GLY D CA  1 
ATOM   7057  C  C   . GLY D 1 138 ? 85.757  106.147 39.899  1.00 40.14  ? 138 GLY D C   1 
ATOM   7058  O  O   . GLY D 1 138 ? 86.914  106.576 39.959  1.00 36.05  ? 138 GLY D O   1 
ATOM   7059  N  N   . GLY D 1 139 ? 84.886  106.286 40.902  1.00 39.54  ? 139 GLY D N   1 
ATOM   7060  C  CA  . GLY D 1 139 ? 85.269  106.898 42.159  1.00 32.65  ? 139 GLY D CA  1 
ATOM   7061  C  C   . GLY D 1 139 ? 86.050  106.018 43.114  1.00 32.26  ? 139 GLY D C   1 
ATOM   7062  O  O   . GLY D 1 139 ? 86.478  106.490 44.175  1.00 31.30  ? 139 GLY D O   1 
ATOM   7063  N  N   . TYR D 1 140 ? 86.257  104.751 42.783  1.00 28.19  ? 140 TYR D N   1 
ATOM   7064  C  CA  . TYR D 1 140 ? 86.969  103.824 43.658  1.00 30.92  ? 140 TYR D CA  1 
ATOM   7065  C  C   . TYR D 1 140 ? 88.246  103.391 42.945  1.00 34.01  ? 140 TYR D C   1 
ATOM   7066  O  O   . TYR D 1 140 ? 88.181  102.701 41.923  1.00 35.41  ? 140 TYR D O   1 
ATOM   7067  C  CB  . TYR D 1 140 ? 86.093  102.617 44.005  1.00 30.54  ? 140 TYR D CB  1 
ATOM   7068  C  CG  . TYR D 1 140 ? 84.978  102.908 45.003  1.00 32.31  ? 140 TYR D CG  1 
ATOM   7069  C  CD1 . TYR D 1 140 ? 85.258  103.101 46.358  1.00 28.53  ? 140 TYR D CD1 1 
ATOM   7070  C  CD2 . TYR D 1 140 ? 83.644  102.979 44.589  1.00 31.66  ? 140 TYR D CD2 1 
ATOM   7071  C  CE1 . TYR D 1 140 ? 84.236  103.358 47.277  1.00 29.90  ? 140 TYR D CE1 1 
ATOM   7072  C  CE2 . TYR D 1 140 ? 82.616  103.238 45.498  1.00 27.38  ? 140 TYR D CE2 1 
ATOM   7073  C  CZ  . TYR D 1 140 ? 82.921  103.422 46.836  1.00 27.24  ? 140 TYR D CZ  1 
ATOM   7074  O  OH  . TYR D 1 140 ? 81.915  103.675 47.733  1.00 31.87  ? 140 TYR D OH  1 
ATOM   7075  N  N   . ILE D 1 141 ? 89.397  103.788 43.487  1.00 34.76  ? 141 ILE D N   1 
ATOM   7076  C  CA  . ILE D 1 141 ? 90.702  103.556 42.864  1.00 36.54  ? 141 ILE D CA  1 
ATOM   7077  C  C   . ILE D 1 141 ? 91.277  102.266 43.439  1.00 33.12  ? 141 ILE D C   1 
ATOM   7078  O  O   . ILE D 1 141 ? 91.841  102.257 44.535  1.00 33.56  ? 141 ILE D O   1 
ATOM   7079  C  CB  . ILE D 1 141 ? 91.651  104.736 43.080  1.00 36.85  ? 141 ILE D CB  1 
ATOM   7080  C  CG1 . ILE D 1 141 ? 91.003  106.030 42.600  1.00 34.02  ? 141 ILE D CG1 1 
ATOM   7081  C  CG2 . ILE D 1 141 ? 92.976  104.511 42.343  1.00 39.94  ? 141 ILE D CG2 1 
ATOM   7082  C  CD1 . ILE D 1 141 ? 90.436  105.942 41.223  1.00 32.70  ? 141 ILE D CD1 1 
ATOM   7083  N  N   . ARG D 1 142 ? 91.163  101.180 42.668  1.00 36.52  ? 142 ARG D N   1 
ATOM   7084  C  CA  . ARG D 1 142 ? 91.660  99.874  43.099  1.00 40.97  ? 142 ARG D CA  1 
ATOM   7085  C  C   . ARG D 1 142 ? 93.140  99.912  43.475  1.00 40.96  ? 142 ARG D C   1 
ATOM   7086  O  O   . ARG D 1 142 ? 93.568  99.194  44.385  1.00 38.62  ? 142 ARG D O   1 
ATOM   7087  C  CB  . ARG D 1 142 ? 91.435  98.841  41.997  1.00 42.82  ? 142 ARG D CB  1 
ATOM   7088  C  CG  . ARG D 1 142 ? 89.982  98.500  41.763  1.00 50.49  ? 142 ARG D CG  1 
ATOM   7089  C  CD  . ARG D 1 142 ? 89.829  97.093  41.236  1.00 50.42  ? 142 ARG D CD  1 
ATOM   7090  N  NE  . ARG D 1 142 ? 89.451  96.170  42.294  1.00 53.85  ? 142 ARG D NE  1 
ATOM   7091  C  CZ  . ARG D 1 142 ? 88.445  95.312  42.205  1.00 60.05  ? 142 ARG D CZ  1 
ATOM   7092  N  NH1 . ARG D 1 142 ? 87.667  95.271  41.135  1.00 61.80  ? 142 ARG D NH1 1 
ATOM   7093  N  NH2 . ARG D 1 142 ? 88.212  94.480  43.220  1.00 60.25  ? 142 ARG D NH2 1 
ATOM   7094  N  N   . ALA D 1 143 ? 93.942  100.717 42.769  1.00 40.65  ? 143 ALA D N   1 
ATOM   7095  C  CA  . ALA D 1 143 ? 95.367  100.787 43.082  1.00 44.21  ? 143 ALA D CA  1 
ATOM   7096  C  C   . ALA D 1 143 ? 95.610  101.312 44.496  1.00 45.03  ? 143 ALA D C   1 
ATOM   7097  O  O   . ALA D 1 143 ? 96.630  100.977 45.117  1.00 43.70  ? 143 ALA D O   1 
ATOM   7098  C  CB  . ALA D 1 143 ? 96.093  101.655 42.050  1.00 41.74  ? 143 ALA D CB  1 
ATOM   7099  N  N   . ASP D 1 144 ? 94.684  102.114 45.028  1.00 38.72  ? 144 ASP D N   1 
ATOM   7100  C  CA  . ASP D 1 144 ? 94.814  102.595 46.398  1.00 37.80  ? 144 ASP D CA  1 
ATOM   7101  C  C   . ASP D 1 144 ? 94.464  101.513 47.416  1.00 39.54  ? 144 ASP D C   1 
ATOM   7102  O  O   . ASP D 1 144 ? 95.294  101.150 48.257  1.00 34.23  ? 144 ASP D O   1 
ATOM   7103  C  CB  . ASP D 1 144 ? 93.924  103.813 46.619  1.00 37.20  ? 144 ASP D CB  1 
ATOM   7104  C  CG  . ASP D 1 144 ? 94.573  105.095 46.167  1.00 40.85  ? 144 ASP D CG  1 
ATOM   7105  O  OD1 . ASP D 1 144 ? 95.800  105.073 45.933  1.00 38.91  ? 144 ASP D OD1 1 
ATOM   7106  O  OD2 . ASP D 1 144 ? 93.865  106.121 46.061  1.00 37.84  ? 144 ASP D OD2 1 
ATOM   7107  N  N   . PHE D 1 145 ? 93.227  101.002 47.377  1.00 37.28  ? 145 PHE D N   1 
ATOM   7108  C  CA  . PHE D 1 145 ? 92.729  100.223 48.505  1.00 34.31  ? 145 PHE D CA  1 
ATOM   7109  C  C   . PHE D 1 145 ? 92.825  98.711  48.323  1.00 35.79  ? 145 PHE D C   1 
ATOM   7110  O  O   . PHE D 1 145 ? 92.738  97.992  49.319  1.00 35.58  ? 145 PHE D O   1 
ATOM   7111  C  CB  . PHE D 1 145 ? 91.276  100.624 48.848  1.00 29.98  ? 145 PHE D CB  1 
ATOM   7112  C  CG  . PHE D 1 145 ? 90.277  100.337 47.762  1.00 29.44  ? 145 PHE D CG  1 
ATOM   7113  C  CD1 . PHE D 1 145 ? 89.794  99.048  47.559  1.00 29.00  ? 145 PHE D CD1 1 
ATOM   7114  C  CD2 . PHE D 1 145 ? 89.822  101.358 46.941  1.00 29.44  ? 145 PHE D CD2 1 
ATOM   7115  C  CE1 . PHE D 1 145 ? 88.882  98.785  46.553  1.00 30.07  ? 145 PHE D CE1 1 
ATOM   7116  C  CE2 . PHE D 1 145 ? 88.908  101.100 45.921  1.00 33.23  ? 145 PHE D CE2 1 
ATOM   7117  C  CZ  . PHE D 1 145 ? 88.438  99.813  45.730  1.00 30.90  ? 145 PHE D CZ  1 
ATOM   7118  N  N   . ASP D 1 146 ? 93.036  98.198  47.108  1.00 38.79  ? 146 ASP D N   1 
ATOM   7119  C  CA  . ASP D 1 146 ? 93.117  96.746  46.901  1.00 40.23  ? 146 ASP D CA  1 
ATOM   7120  C  C   . ASP D 1 146 ? 94.580  96.298  46.950  1.00 45.82  ? 146 ASP D C   1 
ATOM   7121  O  O   . ASP D 1 146 ? 95.227  96.062  45.929  1.00 40.92  ? 146 ASP D O   1 
ATOM   7122  C  CB  . ASP D 1 146 ? 92.448  96.350  45.587  1.00 40.76  ? 146 ASP D CB  1 
ATOM   7123  C  CG  . ASP D 1 146 ? 92.281  94.841  45.450  1.00 47.83  ? 146 ASP D CG  1 
ATOM   7124  O  OD1 . ASP D 1 146 ? 92.591  94.120  46.419  1.00 47.17  ? 146 ASP D OD1 1 
ATOM   7125  O  OD2 . ASP D 1 146 ? 91.837  94.373  44.381  1.00 48.96  ? 146 ASP D OD2 1 
ATOM   7126  N  N   . ARG D 1 147 ? 95.091  96.141  48.171  1.00 48.18  ? 147 ARG D N   1 
ATOM   7127  C  CA  . ARG D 1 147 ? 96.482  95.750  48.413  1.00 50.91  ? 147 ARG D CA  1 
ATOM   7128  C  C   . ARG D 1 147 ? 96.505  94.582  49.389  1.00 56.30  ? 147 ARG D C   1 
ATOM   7129  O  O   . ARG D 1 147 ? 95.956  94.698  50.508  1.00 48.37  ? 147 ARG D O   1 
ATOM   7130  C  CB  . ARG D 1 147 ? 97.294  96.929  48.959  1.00 46.67  ? 147 ARG D CB  1 
ATOM   7131  C  CG  . ARG D 1 147 ? 97.422  98.102  47.998  1.00 41.85  ? 147 ARG D CG  1 
ATOM   7132  C  CD  . ARG D 1 147 ? 98.023  99.302  48.703  1.00 41.14  ? 147 ARG D CD  1 
ATOM   7133  N  NE  . ARG D 1 147 ? 98.067  100.469 47.832  1.00 41.29  ? 147 ARG D NE  1 
ATOM   7134  C  CZ  . ARG D 1 147 ? 99.120  101.262 47.697  1.00 42.43  ? 147 ARG D CZ  1 
ATOM   7135  N  NH1 . ARG D 1 147 ? 100.242 101.043 48.368  1.00 44.53  ? 147 ARG D NH1 1 
ATOM   7136  N  NH2 . ARG D 1 147 ? 99.046  102.301 46.872  1.00 40.43  ? 147 ARG D NH2 1 
ATOM   7137  N  N   . PRO D 1 148 ? 97.124  93.449  49.037  1.00 60.58  ? 148 PRO D N   1 
ATOM   7138  C  CA  . PRO D 1 148 ? 97.041  92.261  49.911  1.00 63.30  ? 148 PRO D CA  1 
ATOM   7139  C  C   . PRO D 1 148 ? 97.785  92.397  51.236  1.00 60.65  ? 148 PRO D C   1 
ATOM   7140  O  O   . PRO D 1 148 ? 97.510  91.619  52.161  1.00 58.33  ? 148 PRO D O   1 
ATOM   7141  C  CB  . PRO D 1 148 ? 97.645  91.144  49.043  1.00 65.04  ? 148 PRO D CB  1 
ATOM   7142  C  CG  . PRO D 1 148 ? 97.506  91.653  47.630  1.00 64.61  ? 148 PRO D CG  1 
ATOM   7143  C  CD  . PRO D 1 148 ? 97.733  93.133  47.736  1.00 59.62  ? 148 PRO D CD  1 
ATOM   7144  N  N   . ASP D 1 149 ? 98.704  93.356  51.357  1.00 55.20  ? 149 ASP D N   1 
ATOM   7145  C  CA  . ASP D 1 149 ? 99.490  93.564  52.568  1.00 52.44  ? 149 ASP D CA  1 
ATOM   7146  C  C   . ASP D 1 149 ? 98.746  94.323  53.664  1.00 54.10  ? 149 ASP D C   1 
ATOM   7147  O  O   . ASP D 1 149 ? 99.280  94.453  54.772  1.00 48.91  ? 149 ASP D O   1 
ATOM   7148  C  CB  . ASP D 1 149 ? 100.757 94.335  52.207  1.00 54.76  ? 149 ASP D CB  1 
ATOM   7149  C  CG  . ASP D 1 149 ? 100.470 95.499  51.268  1.00 56.74  ? 149 ASP D CG  1 
ATOM   7150  O  OD1 . ASP D 1 149 ? 99.952  95.251  50.151  1.00 52.60  ? 149 ASP D OD1 1 
ATOM   7151  O  OD2 . ASP D 1 149 ? 100.742 96.658  51.656  1.00 55.48  ? 149 ASP D OD2 1 
ATOM   7152  N  N   . VAL D 1 150 ? 97.545  94.834  53.386  1.00 51.40  ? 150 VAL D N   1 
ATOM   7153  C  CA  . VAL D 1 150 ? 96.866  95.767  54.279  1.00 45.25  ? 150 VAL D CA  1 
ATOM   7154  C  C   . VAL D 1 150 ? 96.129  94.997  55.363  1.00 41.91  ? 150 VAL D C   1 
ATOM   7155  O  O   . VAL D 1 150 ? 95.360  94.075  55.067  1.00 38.27  ? 150 VAL D O   1 
ATOM   7156  C  CB  . VAL D 1 150 ? 95.901  96.668  53.496  1.00 43.70  ? 150 VAL D CB  1 
ATOM   7157  C  CG1 . VAL D 1 150 ? 95.083  97.518  54.454  1.00 40.84  ? 150 VAL D CG1 1 
ATOM   7158  C  CG2 . VAL D 1 150 ? 96.669  97.545  52.519  1.00 46.10  ? 150 VAL D CG2 1 
ATOM   7159  N  N   . LYS D 1 151 ? 96.387  95.359  56.624  1.00 37.31  ? 151 LYS D N   1 
ATOM   7160  C  CA  . LYS D 1 151 ? 95.608  94.846  57.745  1.00 36.16  ? 151 LYS D CA  1 
ATOM   7161  C  C   . LYS D 1 151 ? 94.342  95.685  57.896  1.00 34.59  ? 151 LYS D C   1 
ATOM   7162  O  O   . LYS D 1 151 ? 94.423  96.890  58.147  1.00 33.62  ? 151 LYS D O   1 
ATOM   7163  C  CB  . LYS D 1 151 ? 96.426  94.871  59.033  1.00 38.14  ? 151 LYS D CB  1 
ATOM   7164  C  CG  . LYS D 1 151 ? 97.308  93.636  59.233  1.00 47.10  ? 151 LYS D CG  1 
ATOM   7165  C  CD  . LYS D 1 151 ? 97.747  93.469  60.689  1.00 51.16  ? 151 LYS D CD  1 
ATOM   7166  C  CE  . LYS D 1 151 ? 96.576  93.640  61.662  1.00 54.05  ? 151 LYS D CE  1 
ATOM   7167  N  NZ  . LYS D 1 151 ? 96.665  92.694  62.826  1.00 60.53  ? 151 LYS D NZ  1 
ATOM   7168  N  N   . TRP D 1 152 ? 93.181  95.050  57.728  1.00 31.04  ? 152 TRP D N   1 
ATOM   7169  C  CA  . TRP D 1 152 ? 91.883  95.705  57.820  1.00 33.23  ? 152 TRP D CA  1 
ATOM   7170  C  C   . TRP D 1 152 ? 91.153  95.265  59.078  1.00 29.90  ? 152 TRP D C   1 
ATOM   7171  O  O   . TRP D 1 152 ? 91.169  94.084  59.430  1.00 36.70  ? 152 TRP D O   1 
ATOM   7172  C  CB  . TRP D 1 152 ? 90.996  95.353  56.633  1.00 32.43  ? 152 TRP D CB  1 
ATOM   7173  C  CG  . TRP D 1 152 ? 91.404  95.906  55.320  1.00 30.86  ? 152 TRP D CG  1 
ATOM   7174  C  CD1 . TRP D 1 152 ? 92.035  95.236  54.322  1.00 28.73  ? 152 TRP D CD1 1 
ATOM   7175  C  CD2 . TRP D 1 152 ? 91.150  97.227  54.823  1.00 29.56  ? 152 TRP D CD2 1 
ATOM   7176  N  NE1 . TRP D 1 152 ? 92.211  96.056  53.234  1.00 33.30  ? 152 TRP D NE1 1 
ATOM   7177  C  CE2 . TRP D 1 152 ? 91.680  97.288  53.517  1.00 34.28  ? 152 TRP D CE2 1 
ATOM   7178  C  CE3 . TRP D 1 152 ? 90.536  98.364  55.356  1.00 30.90  ? 152 TRP D CE3 1 
ATOM   7179  C  CZ2 . TRP D 1 152 ? 91.623  98.449  52.736  1.00 32.11  ? 152 TRP D CZ2 1 
ATOM   7180  C  CZ3 . TRP D 1 152 ? 90.484  99.526  54.576  1.00 30.05  ? 152 TRP D CZ3 1 
ATOM   7181  C  CH2 . TRP D 1 152 ? 91.016  99.552  53.283  1.00 29.60  ? 152 TRP D CH2 1 
ATOM   7182  N  N   . HIS D 1 153 ? 90.499  96.213  59.747  1.00 31.25  ? 153 HIS D N   1 
ATOM   7183  C  CA  . HIS D 1 153 ? 89.434  95.914  60.703  1.00 28.04  ? 153 HIS D CA  1 
ATOM   7184  C  C   . HIS D 1 153 ? 88.144  96.434  60.078  1.00 28.71  ? 153 HIS D C   1 
ATOM   7185  O  O   . HIS D 1 153 ? 87.927  97.650  60.014  1.00 27.77  ? 153 HIS D O   1 
ATOM   7186  C  CB  . HIS D 1 153 ? 89.670  96.560  62.067  1.00 26.38  ? 153 HIS D CB  1 
ATOM   7187  C  CG  . HIS D 1 153 ? 88.550  96.312  63.046  1.00 30.60  ? 153 HIS D CG  1 
ATOM   7188  N  ND1 . HIS D 1 153 ? 88.328  97.108  64.151  1.00 25.68  ? 153 HIS D ND1 1 
ATOM   7189  C  CD2 . HIS D 1 153 ? 87.590  95.354  63.078  1.00 27.53  ? 153 HIS D CD2 1 
ATOM   7190  C  CE1 . HIS D 1 153 ? 87.287  96.648  64.823  1.00 29.66  ? 153 HIS D CE1 1 
ATOM   7191  N  NE2 . HIS D 1 153 ? 86.820  95.585  64.195  1.00 29.75  ? 153 HIS D NE2 1 
ATOM   7192  N  N   . LEU D 1 154 ? 87.301  95.531  59.594  1.00 23.94  ? 154 LEU D N   1 
ATOM   7193  C  CA  . LEU D 1 154 ? 86.062  95.946  58.946  1.00 29.13  ? 154 LEU D CA  1 
ATOM   7194  C  C   . LEU D 1 154 ? 84.950  95.993  59.993  1.00 27.91  ? 154 LEU D C   1 
ATOM   7195  O  O   . LEU D 1 154 ? 84.674  94.990  60.662  1.00 31.72  ? 154 LEU D O   1 
ATOM   7196  C  CB  . LEU D 1 154 ? 85.700  95.004  57.799  1.00 27.62  ? 154 LEU D CB  1 
ATOM   7197  C  CG  . LEU D 1 154 ? 86.771  94.791  56.725  1.00 27.48  ? 154 LEU D CG  1 
ATOM   7198  C  CD1 . LEU D 1 154 ? 86.280  93.808  55.647  1.00 23.33  ? 154 LEU D CD1 1 
ATOM   7199  C  CD2 . LEU D 1 154 ? 87.209  96.120  56.090  1.00 23.40  ? 154 LEU D CD2 1 
ATOM   7200  N  N   . LEU D 1 155 ? 84.332  97.157  60.153  1.00 21.32  ? 155 LEU D N   1 
ATOM   7201  C  CA  . LEU D 1 155 ? 83.291  97.307  61.165  1.00 26.68  ? 155 LEU D CA  1 
ATOM   7202  C  C   . LEU D 1 155 ? 81.949  96.800  60.645  1.00 27.42  ? 155 LEU D C   1 
ATOM   7203  O  O   . LEU D 1 155 ? 81.647  96.892  59.453  1.00 23.03  ? 155 LEU D O   1 
ATOM   7204  C  CB  . LEU D 1 155 ? 83.148  98.772  61.573  1.00 21.94  ? 155 LEU D CB  1 
ATOM   7205  C  CG  . LEU D 1 155 ? 84.388  99.480  62.131  1.00 24.16  ? 155 LEU D CG  1 
ATOM   7206  C  CD1 . LEU D 1 155 ? 84.057  100.924 62.454  1.00 21.26  ? 155 LEU D CD1 1 
ATOM   7207  C  CD2 . LEU D 1 155 ? 84.917  98.768  63.366  1.00 21.44  ? 155 LEU D CD2 1 
ATOM   7208  N  N   . GLU D 1 156 ? 81.130  96.281  61.555  1.00 30.49  ? 156 GLU D N   1 
ATOM   7209  C  CA  . GLU D 1 156 ? 79.796  95.822  61.203  1.00 33.78  ? 156 GLU D CA  1 
ATOM   7210  C  C   . GLU D 1 156 ? 78.762  96.897  61.556  1.00 34.22  ? 156 GLU D C   1 
ATOM   7211  O  O   . GLU D 1 156 ? 79.082  97.944  62.134  1.00 30.77  ? 156 GLU D O   1 
ATOM   7212  C  CB  . GLU D 1 156 ? 79.490  94.493  61.907  1.00 37.95  ? 156 GLU D CB  1 
ATOM   7213  C  CG  . GLU D 1 156 ? 80.608  93.438  61.798  1.00 32.63  ? 156 GLU D CG  1 
ATOM   7214  C  CD  . GLU D 1 156 ? 80.519  92.607  60.515  1.00 34.85  ? 156 GLU D CD  1 
ATOM   7215  O  OE1 . GLU D 1 156 ? 79.587  92.833  59.724  1.00 41.47  ? 156 GLU D OE1 1 
ATOM   7216  O  OE2 . GLU D 1 156 ? 81.368  91.722  60.293  1.00 34.26  ? 156 GLU D OE2 1 
ATOM   7217  N  N   . GLY D 1 157 ? 77.495  96.668  61.210  1.00 37.98  ? 157 GLY D N   1 
ATOM   7218  C  CA  . GLY D 1 157 ? 76.432  97.668  61.451  1.00 33.95  ? 157 GLY D CA  1 
ATOM   7219  C  C   . GLY D 1 157 ? 76.259  98.021  62.917  1.00 40.57  ? 157 GLY D C   1 
ATOM   7220  O  O   . GLY D 1 157 ? 75.931  99.174  63.205  1.00 42.25  ? 157 GLY D O   1 
ATOM   7221  N  N   . HIS D 1 158 ? 76.526  97.075  63.808  1.00 38.80  ? 158 HIS D N   1 
ATOM   7222  C  CA  . HIS D 1 158 ? 76.380  97.300  65.266  1.00 47.17  ? 158 HIS D CA  1 
ATOM   7223  C  C   . HIS D 1 158 ? 77.625  97.976  65.842  1.00 43.05  ? 158 HIS D C   1 
ATOM   7224  O  O   . HIS D 1 158 ? 77.710  98.111  67.068  1.00 39.06  ? 158 HIS D O   1 
ATOM   7225  C  CB  . HIS D 1 158 ? 76.105  95.973  65.978  1.00 50.08  ? 158 HIS D CB  1 
ATOM   7226  C  CG  . HIS D 1 158 ? 74.794  95.339  65.636  1.00 58.10  ? 158 HIS D CG  1 
ATOM   7227  N  ND1 . HIS D 1 158 ? 74.581  94.613  64.484  1.00 76.75  ? 158 HIS D ND1 1 
ATOM   7228  C  CD2 . HIS D 1 158 ? 73.637  95.305  66.305  1.00 64.79  ? 158 HIS D CD2 1 
ATOM   7229  C  CE1 . HIS D 1 158 ? 73.332  94.169  64.470  1.00 73.16  ? 158 HIS D CE1 1 
ATOM   7230  N  NE2 . HIS D 1 158 ? 72.739  94.582  65.564  1.00 69.03  ? 158 HIS D NE2 1 
ATOM   7231  N  N   . ASP D 1 159 ? 78.542  98.415  64.982  1.00 35.06  ? 159 ASP D N   1 
ATOM   7232  C  CA  . ASP D 1 159 ? 79.807  99.015  65.483  1.00 31.74  ? 159 ASP D CA  1 
ATOM   7233  C  C   . ASP D 1 159 ? 79.700  100.543 65.467  1.00 25.65  ? 159 ASP D C   1 
ATOM   7234  O  O   . ASP D 1 159 ? 80.707  101.190 65.706  1.00 27.08  ? 159 ASP D O   1 
ATOM   7235  C  CB  . ASP D 1 159 ? 81.023  98.466  64.736  1.00 29.11  ? 159 ASP D CB  1 
ATOM   7236  C  CG  . ASP D 1 159 ? 81.326  97.013  65.046  1.00 36.58  ? 159 ASP D CG  1 
ATOM   7237  O  OD1 . ASP D 1 159 ? 81.118  96.611  66.199  1.00 38.16  ? 159 ASP D OD1 1 
ATOM   7238  O  OD2 . ASP D 1 159 ? 81.763  96.302  64.129  1.00 30.42  ? 159 ASP D OD2 1 
ATOM   7239  N  N   . ASP D 1 160 ? 78.510  101.077 65.193  1.00 25.79  ? 160 ASP D N   1 
ATOM   7240  C  CA  . ASP D 1 160 ? 78.329  102.520 65.241  1.00 25.94  ? 160 ASP D CA  1 
ATOM   7241  C  C   . ASP D 1 160 ? 78.811  103.056 66.582  1.00 23.16  ? 160 ASP D C   1 
ATOM   7242  O  O   . ASP D 1 160 ? 78.577  102.450 67.625  1.00 28.12  ? 160 ASP D O   1 
ATOM   7243  C  CB  . ASP D 1 160 ? 76.855  102.886 65.024  1.00 23.48  ? 160 ASP D CB  1 
ATOM   7244  C  CG  . ASP D 1 160 ? 76.670  104.334 64.590  1.00 25.73  ? 160 ASP D CG  1 
ATOM   7245  O  OD1 . ASP D 1 160 ? 77.677  105.073 64.502  1.00 23.94  ? 160 ASP D OD1 1 
ATOM   7246  O  OD2 . ASP D 1 160 ? 75.517  104.736 64.322  1.00 33.23  ? 160 ASP D OD2 1 
ATOM   7247  N  N   . GLY D 1 161 ? 79.501  104.191 66.551  1.00 24.19  ? 161 GLY D N   1 
ATOM   7248  C  CA  . GLY D 1 161 ? 80.131  104.713 67.753  1.00 23.61  ? 161 GLY D CA  1 
ATOM   7249  C  C   . GLY D 1 161 ? 81.507  104.156 68.071  1.00 26.23  ? 161 GLY D C   1 
ATOM   7250  O  O   . GLY D 1 161 ? 82.080  104.540 69.101  1.00 28.50  ? 161 GLY D O   1 
ATOM   7251  N  N   . TYR D 1 162 ? 82.071  103.302 67.211  1.00 24.58  ? 162 TYR D N   1 
ATOM   7252  C  CA  . TYR D 1 162 ? 83.325  102.612 67.525  1.00 24.61  ? 162 TYR D CA  1 
ATOM   7253  C  C   . TYR D 1 162 ? 84.395  103.558 68.055  1.00 28.62  ? 162 TYR D C   1 
ATOM   7254  O  O   . TYR D 1 162 ? 84.694  104.587 67.445  1.00 28.53  ? 162 TYR D O   1 
ATOM   7255  C  CB  . TYR D 1 162 ? 83.860  101.893 66.295  1.00 23.53  ? 162 TYR D CB  1 
ATOM   7256  C  CG  . TYR D 1 162 ? 85.019  100.979 66.627  1.00 29.19  ? 162 TYR D CG  1 
ATOM   7257  C  CD1 . TYR D 1 162 ? 84.807  99.697  67.153  1.00 28.03  ? 162 TYR D CD1 1 
ATOM   7258  C  CD2 . TYR D 1 162 ? 86.333  101.394 66.430  1.00 27.63  ? 162 TYR D CD2 1 
ATOM   7259  C  CE1 . TYR D 1 162 ? 85.884  98.856  67.447  1.00 27.50  ? 162 TYR D CE1 1 
ATOM   7260  C  CE2 . TYR D 1 162 ? 87.399  100.567 66.736  1.00 24.31  ? 162 TYR D CE2 1 
ATOM   7261  C  CZ  . TYR D 1 162 ? 87.176  99.308  67.243  1.00 26.61  ? 162 TYR D CZ  1 
ATOM   7262  O  OH  . TYR D 1 162 ? 88.260  98.500  67.528  1.00 31.62  ? 162 TYR D OH  1 
ATOM   7263  N  N   . ASP D 1 163 ? 84.979  103.186 69.193  1.00 28.24  ? 163 ASP D N   1 
ATOM   7264  C  CA  . ASP D 1 163 ? 85.941  104.017 69.909  1.00 28.62  ? 163 ASP D CA  1 
ATOM   7265  C  C   . ASP D 1 163 ? 87.347  103.466 69.662  1.00 27.93  ? 163 ASP D C   1 
ATOM   7266  O  O   . ASP D 1 163 ? 87.711  102.422 70.199  1.00 27.06  ? 163 ASP D O   1 
ATOM   7267  C  CB  . ASP D 1 163 ? 85.585  104.037 71.391  1.00 29.33  ? 163 ASP D CB  1 
ATOM   7268  C  CG  . ASP D 1 163 ? 86.423  105.021 72.195  1.00 30.29  ? 163 ASP D CG  1 
ATOM   7269  O  OD1 . ASP D 1 163 ? 87.596  105.304 71.834  1.00 27.96  ? 163 ASP D OD1 1 
ATOM   7270  O  OD2 . ASP D 1 163 ? 85.873  105.525 73.191  1.00 33.00  ? 163 ASP D OD2 1 
ATOM   7271  N  N   . VAL D 1 164 ? 88.139  104.184 68.864  1.00 24.79  ? 164 VAL D N   1 
ATOM   7272  C  CA  . VAL D 1 164 ? 89.403  103.634 68.381  1.00 26.64  ? 164 VAL D CA  1 
ATOM   7273  C  C   . VAL D 1 164 ? 90.322  103.270 69.548  1.00 29.03  ? 164 VAL D C   1 
ATOM   7274  O  O   . VAL D 1 164 ? 90.864  102.160 69.608  1.00 26.78  ? 164 VAL D O   1 
ATOM   7275  C  CB  . VAL D 1 164 ? 90.075  104.620 67.411  1.00 27.67  ? 164 VAL D CB  1 
ATOM   7276  C  CG1 . VAL D 1 164 ? 91.485  104.144 67.062  1.00 28.47  ? 164 VAL D CG1 1 
ATOM   7277  C  CG2 . VAL D 1 164 ? 89.242  104.760 66.146  1.00 25.35  ? 164 VAL D CG2 1 
ATOM   7278  N  N   . PHE D 1 165 ? 90.480  104.182 70.508  1.00 27.97  ? 165 PHE D N   1 
ATOM   7279  C  CA  . PHE D 1 165 ? 91.386  103.983 71.633  1.00 31.25  ? 165 PHE D CA  1 
ATOM   7280  C  C   . PHE D 1 165 ? 90.691  103.567 72.924  1.00 35.33  ? 165 PHE D C   1 
ATOM   7281  O  O   . PHE D 1 165 ? 91.381  103.260 73.903  1.00 39.03  ? 165 PHE D O   1 
ATOM   7282  C  CB  . PHE D 1 165 ? 92.181  105.268 71.907  1.00 33.09  ? 165 PHE D CB  1 
ATOM   7283  C  CG  . PHE D 1 165 ? 93.233  105.567 70.879  1.00 31.54  ? 165 PHE D CG  1 
ATOM   7284  C  CD1 . PHE D 1 165 ? 94.328  104.731 70.726  1.00 33.40  ? 165 PHE D CD1 1 
ATOM   7285  C  CD2 . PHE D 1 165 ? 93.134  106.695 70.082  1.00 30.13  ? 165 PHE D CD2 1 
ATOM   7286  C  CE1 . PHE D 1 165 ? 95.310  105.015 69.790  1.00 34.58  ? 165 PHE D CE1 1 
ATOM   7287  C  CE2 . PHE D 1 165 ? 94.105  106.983 69.149  1.00 33.60  ? 165 PHE D CE2 1 
ATOM   7288  C  CZ  . PHE D 1 165 ? 95.197  106.147 68.999  1.00 31.03  ? 165 PHE D CZ  1 
ATOM   7289  N  N   . GLY D 1 166 ? 89.360  103.579 72.972  1.00 32.16  ? 166 GLY D N   1 
ATOM   7290  C  CA  . GLY D 1 166 ? 88.662  103.242 74.195  1.00 29.77  ? 166 GLY D CA  1 
ATOM   7291  C  C   . GLY D 1 166 ? 88.521  104.369 75.196  1.00 35.67  ? 166 GLY D C   1 
ATOM   7292  O  O   . GLY D 1 166 ? 88.113  104.114 76.335  1.00 29.56  ? 166 GLY D O   1 
ATOM   7293  N  N   . ASP D 1 167 ? 88.812  105.613 74.806  1.00 32.25  ? 167 ASP D N   1 
ATOM   7294  C  CA  . ASP D 1 167 ? 88.847  106.736 75.739  1.00 33.93  ? 167 ASP D CA  1 
ATOM   7295  C  C   . ASP D 1 167 ? 88.068  107.942 75.224  1.00 37.23  ? 167 ASP D C   1 
ATOM   7296  O  O   . ASP D 1 167 ? 88.368  109.073 75.617  1.00 37.33  ? 167 ASP D O   1 
ATOM   7297  C  CB  . ASP D 1 167 ? 90.294  107.146 76.020  1.00 32.28  ? 167 ASP D CB  1 
ATOM   7298  C  CG  . ASP D 1 167 ? 90.986  107.714 74.786  1.00 38.53  ? 167 ASP D CG  1 
ATOM   7299  O  OD1 . ASP D 1 167 ? 90.353  107.737 73.708  1.00 35.59  ? 167 ASP D OD1 1 
ATOM   7300  O  OD2 . ASP D 1 167 ? 92.163  108.131 74.882  1.00 39.18  ? 167 ASP D OD2 1 
ATOM   7301  N  N   . ASP D 1 168 ? 87.127  107.732 74.302  1.00 34.97  ? 168 ASP D N   1 
ATOM   7302  C  CA  . ASP D 1 168 ? 86.270  108.756 73.714  1.00 31.78  ? 168 ASP D CA  1 
ATOM   7303  C  C   . ASP D 1 168 ? 87.021  109.788 72.898  1.00 33.38  ? 168 ASP D C   1 
ATOM   7304  O  O   . ASP D 1 168 ? 86.423  110.789 72.523  1.00 36.49  ? 168 ASP D O   1 
ATOM   7305  C  CB  . ASP D 1 168 ? 85.439  109.493 74.768  1.00 37.58  ? 168 ASP D CB  1 
ATOM   7306  C  CG  . ASP D 1 168 ? 84.059  108.899 74.928  1.00 45.56  ? 168 ASP D CG  1 
ATOM   7307  O  OD1 . ASP D 1 168 ? 83.205  109.105 74.033  1.00 40.55  ? 168 ASP D OD1 1 
ATOM   7308  O  OD2 . ASP D 1 168 ? 83.837  108.196 75.941  1.00 51.39  ? 168 ASP D OD2 1 
ATOM   7309  N  N   . THR D 1 169 ? 88.300  109.569 72.588  1.00 33.22  ? 169 THR D N   1 
ATOM   7310  C  CA  . THR D 1 169 ? 89.036  110.539 71.776  1.00 35.50  ? 169 THR D CA  1 
ATOM   7311  C  C   . THR D 1 169 ? 88.519  110.582 70.339  1.00 34.89  ? 169 THR D C   1 
ATOM   7312  O  O   . THR D 1 169 ? 88.342  111.663 69.768  1.00 33.56  ? 169 THR D O   1 
ATOM   7313  C  CB  . THR D 1 169 ? 90.533  110.218 71.774  1.00 33.50  ? 169 THR D CB  1 
ATOM   7314  O  OG1 . THR D 1 169 ? 91.063  110.351 73.103  1.00 39.77  ? 169 THR D OG1 1 
ATOM   7315  C  CG2 . THR D 1 169 ? 91.259  111.165 70.857  1.00 36.19  ? 169 THR D CG2 1 
ATOM   7316  N  N   . ILE D 1 170 ? 88.337  109.417 69.718  1.00 32.69  ? 170 ILE D N   1 
ATOM   7317  C  CA  . ILE D 1 170 ? 87.900  109.303 68.328  1.00 33.71  ? 170 ILE D CA  1 
ATOM   7318  C  C   . ILE D 1 170 ? 86.813  108.237 68.245  1.00 31.84  ? 170 ILE D C   1 
ATOM   7319  O  O   . ILE D 1 170 ? 87.017  107.100 68.694  1.00 30.65  ? 170 ILE D O   1 
ATOM   7320  C  CB  . ILE D 1 170 ? 89.055  108.930 67.379  1.00 31.86  ? 170 ILE D CB  1 
ATOM   7321  C  CG1 . ILE D 1 170 ? 90.289  109.804 67.614  1.00 33.00  ? 170 ILE D CG1 1 
ATOM   7322  C  CG2 . ILE D 1 170 ? 88.583  108.967 65.926  1.00 28.93  ? 170 ILE D CG2 1 
ATOM   7323  C  CD1 . ILE D 1 170 ? 91.598  109.127 67.199  1.00 28.25  ? 170 ILE D CD1 1 
ATOM   7324  N  N   . ARG D 1 171 ? 85.682  108.584 67.637  1.00 26.83  ? 171 ARG D N   1 
ATOM   7325  C  CA  . ARG D 1 171 ? 84.598  107.630 67.468  1.00 30.82  ? 171 ARG D CA  1 
ATOM   7326  C  C   . ARG D 1 171 ? 84.059  107.700 66.045  1.00 26.43  ? 171 ARG D C   1 
ATOM   7327  O  O   . ARG D 1 171 ? 83.892  108.790 65.494  1.00 26.37  ? 171 ARG D O   1 
ATOM   7328  C  CB  . ARG D 1 171 ? 83.477  107.905 68.476  1.00 27.41  ? 171 ARG D CB  1 
ATOM   7329  C  CG  . ARG D 1 171 ? 83.744  107.455 69.904  1.00 26.24  ? 171 ARG D CG  1 
ATOM   7330  C  CD  . ARG D 1 171 ? 82.455  107.640 70.712  1.00 31.20  ? 171 ARG D CD  1 
ATOM   7331  N  NE  . ARG D 1 171 ? 82.569  107.213 72.100  1.00 40.53  ? 171 ARG D NE  1 
ATOM   7332  C  CZ  . ARG D 1 171 ? 82.106  106.065 72.584  1.00 40.55  ? 171 ARG D CZ  1 
ATOM   7333  N  NH1 . ARG D 1 171 ? 81.462  105.199 71.817  1.00 32.79  ? 171 ARG D NH1 1 
ATOM   7334  N  NH2 . ARG D 1 171 ? 82.295  105.780 73.871  1.00 36.90  ? 171 ARG D NH2 1 
ATOM   7335  N  N   . PHE D 1 172 ? 83.793  106.535 65.451  1.00 27.07  ? 172 PHE D N   1 
ATOM   7336  C  CA  . PHE D 1 172 ? 83.069  106.492 64.182  1.00 23.19  ? 172 PHE D CA  1 
ATOM   7337  C  C   . PHE D 1 172 ? 81.615  106.879 64.414  1.00 23.21  ? 172 PHE D C   1 
ATOM   7338  O  O   . PHE D 1 172 ? 80.977  106.369 65.328  1.00 24.41  ? 172 PHE D O   1 
ATOM   7339  C  CB  . PHE D 1 172 ? 83.098  105.091 63.574  1.00 22.84  ? 172 PHE D CB  1 
ATOM   7340  C  CG  . PHE D 1 172 ? 84.375  104.732 62.879  1.00 26.26  ? 172 PHE D CG  1 
ATOM   7341  C  CD1 . PHE D 1 172 ? 85.517  104.419 63.610  1.00 24.46  ? 172 PHE D CD1 1 
ATOM   7342  C  CD2 . PHE D 1 172 ? 84.415  104.637 61.494  1.00 20.25  ? 172 PHE D CD2 1 
ATOM   7343  C  CE1 . PHE D 1 172 ? 86.676  104.050 62.968  1.00 22.55  ? 172 PHE D CE1 1 
ATOM   7344  C  CE2 . PHE D 1 172 ? 85.566  104.271 60.857  1.00 22.88  ? 172 PHE D CE2 1 
ATOM   7345  C  CZ  . PHE D 1 172 ? 86.704  103.978 61.592  1.00 23.25  ? 172 PHE D CZ  1 
ATOM   7346  N  N   . ILE D 1 173 ? 81.081  107.765 63.583  1.00 25.71  ? 173 ILE D N   1 
ATOM   7347  C  CA  . ILE D 1 173 ? 79.657  108.095 63.600  1.00 23.66  ? 173 ILE D CA  1 
ATOM   7348  C  C   . ILE D 1 173 ? 79.119  107.725 62.222  1.00 24.04  ? 173 ILE D C   1 
ATOM   7349  O  O   . ILE D 1 173 ? 79.316  108.477 61.254  1.00 25.94  ? 173 ILE D O   1 
ATOM   7350  C  CB  . ILE D 1 173 ? 79.392  109.573 63.916  1.00 23.92  ? 173 ILE D CB  1 
ATOM   7351  C  CG1 . ILE D 1 173 ? 80.065  110.012 65.237  1.00 21.65  ? 173 ILE D CG1 1 
ATOM   7352  C  CG2 . ILE D 1 173 ? 77.899  109.855 63.890  1.00 21.22  ? 173 ILE D CG2 1 
ATOM   7353  C  CD1 . ILE D 1 173 ? 79.490  109.341 66.457  1.00 28.53  ? 173 ILE D CD1 1 
ATOM   7354  N  N   . PHE D 1 174 ? 78.445  106.574 62.131  1.00 22.10  ? 174 PHE D N   1 
ATOM   7355  C  CA  . PHE D 1 174 ? 77.975  106.061 60.845  1.00 24.17  ? 174 PHE D CA  1 
ATOM   7356  C  C   . PHE D 1 174 ? 77.014  107.051 60.208  1.00 25.41  ? 174 PHE D C   1 
ATOM   7357  O  O   . PHE D 1 174 ? 76.052  107.499 60.846  1.00 24.54  ? 174 PHE D O   1 
ATOM   7358  C  CB  . PHE D 1 174 ? 77.281  104.703 61.021  1.00 22.44  ? 174 PHE D CB  1 
ATOM   7359  C  CG  . PHE D 1 174 ? 78.217  103.575 61.367  1.00 25.70  ? 174 PHE D CG  1 
ATOM   7360  C  CD1 . PHE D 1 174 ? 79.598  103.784 61.435  1.00 23.70  ? 174 PHE D CD1 1 
ATOM   7361  C  CD2 . PHE D 1 174 ? 77.718  102.295 61.626  1.00 23.53  ? 174 PHE D CD2 1 
ATOM   7362  C  CE1 . PHE D 1 174 ? 80.483  102.727 61.747  1.00 22.35  ? 174 PHE D CE1 1 
ATOM   7363  C  CE2 . PHE D 1 174 ? 78.594  101.231 61.931  1.00 25.57  ? 174 PHE D CE2 1 
ATOM   7364  C  CZ  . PHE D 1 174 ? 79.973  101.445 61.998  1.00 22.00  ? 174 PHE D CZ  1 
ATOM   7365  N  N   . THR D 1 175 ? 77.282  107.397 58.949  1.00 20.74  ? 175 THR D N   1 
ATOM   7366  C  CA  . THR D 1 175 ? 76.478  108.365 58.202  1.00 22.02  ? 175 THR D CA  1 
ATOM   7367  C  C   . THR D 1 175 ? 76.306  107.855 56.779  1.00 25.46  ? 175 THR D C   1 
ATOM   7368  O  O   . THR D 1 175 ? 76.855  108.418 55.822  1.00 24.90  ? 175 THR D O   1 
ATOM   7369  C  CB  . THR D 1 175 ? 77.133  109.749 58.217  1.00 24.49  ? 175 THR D CB  1 
ATOM   7370  O  OG1 . THR D 1 175 ? 78.539  109.604 57.959  1.00 25.03  ? 175 THR D OG1 1 
ATOM   7371  C  CG2 . THR D 1 175 ? 76.940  110.407 59.569  1.00 21.32  ? 175 THR D CG2 1 
ATOM   7372  N  N   . PRO D 1 176 ? 75.551  106.773 56.604  1.00 25.13  ? 176 PRO D N   1 
ATOM   7373  C  CA  . PRO D 1 176 ? 75.336  106.232 55.259  1.00 23.60  ? 176 PRO D CA  1 
ATOM   7374  C  C   . PRO D 1 176 ? 74.653  107.247 54.351  1.00 23.17  ? 176 PRO D C   1 
ATOM   7375  O  O   . PRO D 1 176 ? 73.939  108.148 54.799  1.00 22.59  ? 176 PRO D O   1 
ATOM   7376  C  CB  . PRO D 1 176 ? 74.436  105.009 55.506  1.00 22.88  ? 176 PRO D CB  1 
ATOM   7377  C  CG  . PRO D 1 176 ? 73.704  105.353 56.814  1.00 26.05  ? 176 PRO D CG  1 
ATOM   7378  C  CD  . PRO D 1 176 ? 74.731  106.093 57.629  1.00 25.12  ? 176 PRO D CD  1 
ATOM   7379  N  N   . GLY D 1 177 ? 74.885  107.094 53.047  1.00 27.22  ? 177 GLY D N   1 
ATOM   7380  C  CA  . GLY D 1 177 ? 74.153  107.896 52.081  1.00 23.79  ? 177 GLY D CA  1 
ATOM   7381  C  C   . GLY D 1 177 ? 74.995  108.384 50.924  1.00 26.74  ? 177 GLY D C   1 
ATOM   7382  O  O   . GLY D 1 177 ? 74.736  108.041 49.765  1.00 25.63  ? 177 GLY D O   1 
ATOM   7383  N  N   . HIS D 1 178 ? 76.007  109.200 51.239  1.00 27.65  ? 178 HIS D N   1 
ATOM   7384  C  CA  . HIS D 1 178 ? 76.948  109.637 50.218  1.00 27.49  ? 178 HIS D CA  1 
ATOM   7385  C  C   . HIS D 1 178 ? 77.667  108.445 49.600  1.00 27.55  ? 178 HIS D C   1 
ATOM   7386  O  O   . HIS D 1 178 ? 77.845  108.380 48.379  1.00 24.89  ? 178 HIS D O   1 
ATOM   7387  C  CB  . HIS D 1 178 ? 77.966  110.601 50.815  1.00 25.47  ? 178 HIS D CB  1 
ATOM   7388  C  CG  . HIS D 1 178 ? 79.051  110.969 49.858  1.00 28.77  ? 178 HIS D CG  1 
ATOM   7389  N  ND1 . HIS D 1 178 ? 80.324  110.447 49.932  1.00 31.32  ? 178 HIS D ND1 1 
ATOM   7390  C  CD2 . HIS D 1 178 ? 79.040  111.781 48.775  1.00 33.65  ? 178 HIS D CD2 1 
ATOM   7391  C  CE1 . HIS D 1 178 ? 81.054  110.935 48.949  1.00 31.28  ? 178 HIS D CE1 1 
ATOM   7392  N  NE2 . HIS D 1 178 ? 80.301  111.747 48.233  1.00 32.81  ? 178 HIS D NE2 1 
ATOM   7393  N  N   . ALA D 1 179 ? 78.100  107.515 50.438  1.00 25.05  ? 179 ALA D N   1 
ATOM   7394  C  CA  . ALA D 1 179 ? 78.599  106.194 50.095  1.00 28.85  ? 179 ALA D CA  1 
ATOM   7395  C  C   . ALA D 1 179 ? 77.927  105.205 51.036  1.00 22.39  ? 179 ALA D C   1 
ATOM   7396  O  O   . ALA D 1 179 ? 77.465  105.586 52.116  1.00 27.64  ? 179 ALA D O   1 
ATOM   7397  C  CB  . ALA D 1 179 ? 80.130  106.107 50.235  1.00 27.13  ? 179 ALA D CB  1 
ATOM   7398  N  N   . PRO D 1 180 ? 77.821  103.934 50.644  1.00 24.79  ? 180 PRO D N   1 
ATOM   7399  C  CA  . PRO D 1 180 ? 77.084  102.982 51.503  1.00 26.70  ? 180 PRO D CA  1 
ATOM   7400  C  C   . PRO D 1 180 ? 77.688  102.832 52.893  1.00 24.75  ? 180 PRO D C   1 
ATOM   7401  O  O   . PRO D 1 180 ? 76.942  102.773 53.876  1.00 24.20  ? 180 PRO D O   1 
ATOM   7402  C  CB  . PRO D 1 180 ? 77.135  101.672 50.693  1.00 26.62  ? 180 PRO D CB  1 
ATOM   7403  C  CG  . PRO D 1 180 ? 77.216  102.142 49.249  1.00 21.06  ? 180 PRO D CG  1 
ATOM   7404  C  CD  . PRO D 1 180 ? 78.143  103.355 49.324  1.00 22.44  ? 180 PRO D CD  1 
ATOM   7405  N  N   . GLY D 1 181 ? 79.016  102.815 53.013  1.00 22.46  ? 181 GLY D N   1 
ATOM   7406  C  CA  . GLY D 1 181 ? 79.648  102.649 54.307  1.00 21.65  ? 181 GLY D CA  1 
ATOM   7407  C  C   . GLY D 1 181 ? 80.277  103.918 54.844  1.00 26.00  ? 181 GLY D C   1 
ATOM   7408  O  O   . GLY D 1 181 ? 81.236  103.867 55.634  1.00 23.19  ? 181 GLY D O   1 
ATOM   7409  N  N   . HIS D 1 182 ? 79.753  105.070 54.425  1.00 23.24  ? 182 HIS D N   1 
ATOM   7410  C  CA  . HIS D 1 182 ? 80.369  106.316 54.835  1.00 25.18  ? 182 HIS D CA  1 
ATOM   7411  C  C   . HIS D 1 182 ? 80.215  106.523 56.335  1.00 25.68  ? 182 HIS D C   1 
ATOM   7412  O  O   . HIS D 1 182 ? 79.159  106.256 56.929  1.00 24.39  ? 182 HIS D O   1 
ATOM   7413  C  CB  . HIS D 1 182 ? 79.787  107.501 54.077  1.00 26.04  ? 182 HIS D CB  1 
ATOM   7414  C  CG  . HIS D 1 182 ? 80.427  108.801 54.445  1.00 26.25  ? 182 HIS D CG  1 
ATOM   7415  N  ND1 . HIS D 1 182 ? 80.080  109.509 55.582  1.00 23.89  ? 182 HIS D ND1 1 
ATOM   7416  C  CD2 . HIS D 1 182 ? 81.421  109.505 53.850  1.00 28.45  ? 182 HIS D CD2 1 
ATOM   7417  C  CE1 . HIS D 1 182 ? 80.817  110.605 55.657  1.00 26.92  ? 182 HIS D CE1 1 
ATOM   7418  N  NE2 . HIS D 1 182 ? 81.637  110.629 54.617  1.00 29.92  ? 182 HIS D NE2 1 
ATOM   7419  N  N   . SER D 1 183 ? 81.295  106.983 56.945  1.00 22.51  ? 183 SER D N   1 
ATOM   7420  C  CA  . SER D 1 183 ? 81.313  107.307 58.357  1.00 23.01  ? 183 SER D CA  1 
ATOM   7421  C  C   . SER D 1 183 ? 81.879  108.702 58.543  1.00 23.92  ? 183 SER D C   1 
ATOM   7422  O  O   . SER D 1 183 ? 82.822  109.090 57.851  1.00 26.98  ? 183 SER D O   1 
ATOM   7423  C  CB  . SER D 1 183 ? 82.129  106.285 59.150  1.00 24.51  ? 183 SER D CB  1 
ATOM   7424  O  OG  . SER D 1 183 ? 81.904  106.472 60.532  1.00 29.08  ? 183 SER D OG  1 
ATOM   7425  N  N   . SER D 1 184 ? 81.254  109.465 59.432  1.00 24.05  ? 184 SER D N   1 
ATOM   7426  C  CA  . SER D 1 184 ? 81.806  110.693 59.975  1.00 23.78  ? 184 SER D CA  1 
ATOM   7427  C  C   . SER D 1 184 ? 82.620  110.343 61.227  1.00 24.33  ? 184 SER D C   1 
ATOM   7428  O  O   . SER D 1 184 ? 82.719  109.176 61.622  1.00 24.15  ? 184 SER D O   1 
ATOM   7429  C  CB  . SER D 1 184 ? 80.685  111.690 60.284  1.00 20.85  ? 184 SER D CB  1 
ATOM   7430  O  OG  . SER D 1 184 ? 79.938  112.034 59.113  1.00 23.24  ? 184 SER D OG  1 
ATOM   7431  N  N   . PHE D 1 185 ? 83.208  111.353 61.872  1.00 25.09  ? 185 PHE D N   1 
ATOM   7432  C  CA  . PHE D 1 185 ? 83.985  111.111 63.084  1.00 23.83  ? 185 PHE D CA  1 
ATOM   7433  C  C   . PHE D 1 185 ? 83.674  112.174 64.121  1.00 28.54  ? 185 PHE D C   1 
ATOM   7434  O  O   . PHE D 1 185 ? 83.604  113.365 63.793  1.00 25.61  ? 185 PHE D O   1 
ATOM   7435  C  CB  . PHE D 1 185 ? 85.484  111.077 62.776  1.00 24.13  ? 185 PHE D CB  1 
ATOM   7436  C  CG  . PHE D 1 185 ? 85.864  109.946 61.878  1.00 23.33  ? 185 PHE D CG  1 
ATOM   7437  C  CD1 . PHE D 1 185 ? 86.157  108.705 62.401  1.00 23.47  ? 185 PHE D CD1 1 
ATOM   7438  C  CD2 . PHE D 1 185 ? 85.836  110.101 60.503  1.00 23.61  ? 185 PHE D CD2 1 
ATOM   7439  C  CE1 . PHE D 1 185 ? 86.471  107.632 61.568  1.00 26.28  ? 185 PHE D CE1 1 
ATOM   7440  C  CE2 . PHE D 1 185 ? 86.143  109.043 59.671  1.00 24.77  ? 185 PHE D CE2 1 
ATOM   7441  C  CZ  . PHE D 1 185 ? 86.455  107.807 60.201  1.00 24.92  ? 185 PHE D CZ  1 
ATOM   7442  N  N   . LEU D 1 186 ? 83.476  111.728 65.362  1.00 23.83  ? 186 LEU D N   1 
ATOM   7443  C  CA  . LEU D 1 186 ? 83.353  112.595 66.521  1.00 25.19  ? 186 LEU D CA  1 
ATOM   7444  C  C   . LEU D 1 186 ? 84.644  112.499 67.322  1.00 29.89  ? 186 LEU D C   1 
ATOM   7445  O  O   . LEU D 1 186 ? 85.056  111.403 67.717  1.00 29.95  ? 186 LEU D O   1 
ATOM   7446  C  CB  . LEU D 1 186 ? 82.159  112.206 67.393  1.00 23.78  ? 186 LEU D CB  1 
ATOM   7447  C  CG  . LEU D 1 186 ? 82.017  113.103 68.627  1.00 29.04  ? 186 LEU D CG  1 
ATOM   7448  C  CD1 . LEU D 1 186 ? 81.641  114.540 68.212  1.00 26.52  ? 186 LEU D CD1 1 
ATOM   7449  C  CD2 . LEU D 1 186 ? 80.980  112.557 69.564  1.00 26.53  ? 186 LEU D CD2 1 
ATOM   7450  N  N   . LEU D 1 187 ? 85.280  113.639 67.546  1.00 32.70  ? 187 LEU D N   1 
ATOM   7451  C  CA  . LEU D 1 187 ? 86.557  113.722 68.241  1.00 30.91  ? 187 LEU D CA  1 
ATOM   7452  C  C   . LEU D 1 187 ? 86.351  114.501 69.528  1.00 36.60  ? 187 LEU D C   1 
ATOM   7453  O  O   . LEU D 1 187 ? 85.553  115.441 69.564  1.00 33.94  ? 187 LEU D O   1 
ATOM   7454  C  CB  . LEU D 1 187 ? 87.609  114.431 67.373  1.00 31.71  ? 187 LEU D CB  1 
ATOM   7455  C  CG  . LEU D 1 187 ? 88.558  113.621 66.482  1.00 32.19  ? 187 LEU D CG  1 
ATOM   7456  C  CD1 . LEU D 1 187 ? 87.807  112.652 65.601  1.00 33.30  ? 187 LEU D CD1 1 
ATOM   7457  C  CD2 . LEU D 1 187 ? 89.379  114.552 65.616  1.00 37.44  ? 187 LEU D CD2 1 
ATOM   7458  N  N   . ARG D 1 188 ? 87.069  114.116 70.581  1.00 35.03  ? 188 ARG D N   1 
ATOM   7459  C  CA  . ARG D 1 188 ? 87.088  114.890 71.818  1.00 40.34  ? 188 ARG D CA  1 
ATOM   7460  C  C   . ARG D 1 188 ? 88.535  115.120 72.231  1.00 43.24  ? 188 ARG D C   1 
ATOM   7461  O  O   . ARG D 1 188 ? 89.246  114.169 72.577  1.00 40.49  ? 188 ARG D O   1 
ATOM   7462  C  CB  . ARG D 1 188 ? 86.307  114.190 72.931  1.00 36.43  ? 188 ARG D CB  1 
ATOM   7463  C  CG  . ARG D 1 188 ? 84.811  114.098 72.672  1.00 34.85  ? 188 ARG D CG  1 
ATOM   7464  C  CD  . ARG D 1 188 ? 84.123  113.367 73.808  1.00 36.75  ? 188 ARG D CD  1 
ATOM   7465  N  NE  . ARG D 1 188 ? 82.673  113.542 73.834  1.00 37.12  ? 188 ARG D NE  1 
ATOM   7466  C  CZ  . ARG D 1 188 ? 82.054  114.685 74.103  1.00 43.22  ? 188 ARG D CZ  1 
ATOM   7467  N  NH1 . ARG D 1 188 ? 82.729  115.812 74.291  1.00 44.04  ? 188 ARG D NH1 1 
ATOM   7468  N  NH2 . ARG D 1 188 ? 80.727  114.698 74.191  1.00 41.26  ? 188 ARG D NH2 1 
ATOM   7469  N  N   . LEU D 1 189 ? 88.961  116.387 72.192  1.00 41.19  ? 189 LEU D N   1 
ATOM   7470  C  CA  . LEU D 1 189 ? 90.293  116.893 72.489  1.00 41.52  ? 189 LEU D CA  1 
ATOM   7471  C  C   . LEU D 1 189 ? 90.310  117.641 73.817  1.00 39.58  ? 189 LEU D C   1 
ATOM   7472  O  O   . LEU D 1 189 ? 89.340  118.338 74.142  1.00 33.58  ? 189 LEU D O   1 
ATOM   7473  C  CB  . LEU D 1 189 ? 90.748  117.827 71.370  1.00 36.17  ? 189 LEU D CB  1 
ATOM   7474  C  CG  . LEU D 1 189 ? 90.568  117.111 70.037  1.00 40.75  ? 189 LEU D CG  1 
ATOM   7475  C  CD1 . LEU D 1 189 ? 90.216  118.076 68.943  1.00 41.33  ? 189 LEU D CD1 1 
ATOM   7476  C  CD2 . LEU D 1 189 ? 91.857  116.376 69.706  1.00 44.02  ? 189 LEU D CD2 1 
ATOM   7477  N  N   . PRO D 1 190 ? 91.400  117.526 74.590  1.00 40.28  ? 190 PRO D N   1 
ATOM   7478  C  CA  . PRO D 1 190 ? 91.406  118.090 75.954  1.00 39.75  ? 190 PRO D CA  1 
ATOM   7479  C  C   . PRO D 1 190 ? 91.014  119.557 76.016  1.00 37.41  ? 190 PRO D C   1 
ATOM   7480  O  O   . PRO D 1 190 ? 90.205  119.943 76.864  1.00 39.65  ? 190 PRO D O   1 
ATOM   7481  C  CB  . PRO D 1 190 ? 92.859  117.868 76.415  1.00 34.29  ? 190 PRO D CB  1 
ATOM   7482  C  CG  . PRO D 1 190 ? 93.376  116.763 75.573  1.00 38.01  ? 190 PRO D CG  1 
ATOM   7483  C  CD  . PRO D 1 190 ? 92.675  116.870 74.248  1.00 38.75  ? 190 PRO D CD  1 
ATOM   7484  N  N   . GLU D 1 191 ? 91.529  120.385 75.123  1.00 39.08  ? 191 GLU D N   1 
ATOM   7485  C  CA  . GLU D 1 191 ? 91.225  121.803 75.247  1.00 41.79  ? 191 GLU D CA  1 
ATOM   7486  C  C   . GLU D 1 191 ? 90.010  122.226 74.419  1.00 41.56  ? 191 GLU D C   1 
ATOM   7487  O  O   . GLU D 1 191 ? 89.157  122.981 74.903  1.00 37.45  ? 191 GLU D O   1 
ATOM   7488  C  CB  . GLU D 1 191 ? 92.460  122.614 74.849  1.00 41.07  ? 191 GLU D CB  1 
ATOM   7489  C  CG  . GLU D 1 191 ? 93.586  122.483 75.858  1.00 46.86  ? 191 GLU D CG  1 
ATOM   7490  C  CD  . GLU D 1 191 ? 94.888  123.102 75.392  1.00 51.55  ? 191 GLU D CD  1 
ATOM   7491  O  OE1 . GLU D 1 191 ? 94.850  124.254 74.903  1.00 52.59  ? 191 GLU D OE1 1 
ATOM   7492  O  OE2 . GLU D 1 191 ? 95.944  122.443 75.538  1.00 51.46  ? 191 GLU D OE2 1 
ATOM   7493  N  N   . THR D 1 192 ? 89.915  121.763 73.173  1.00 37.64  ? 192 THR D N   1 
ATOM   7494  C  CA  . THR D 1 192 ? 88.836  122.179 72.283  1.00 38.28  ? 192 THR D CA  1 
ATOM   7495  C  C   . THR D 1 192 ? 87.478  121.569 72.637  1.00 37.47  ? 192 THR D C   1 
ATOM   7496  O  O   . THR D 1 192 ? 86.449  122.127 72.257  1.00 38.30  ? 192 THR D O   1 
ATOM   7497  C  CB  . THR D 1 192 ? 89.222  121.813 70.853  1.00 37.55  ? 192 THR D CB  1 
ATOM   7498  O  OG1 . THR D 1 192 ? 90.563  122.268 70.611  1.00 39.19  ? 192 THR D OG1 1 
ATOM   7499  C  CG2 . THR D 1 192 ? 88.258  122.436 69.822  1.00 40.41  ? 192 THR D CG2 1 
ATOM   7500  N  N   . GLY D 1 193 ? 87.438  120.453 73.358  1.00 35.53  ? 193 GLY D N   1 
ATOM   7501  C  CA  . GLY D 1 193 ? 86.204  119.721 73.513  1.00 33.59  ? 193 GLY D CA  1 
ATOM   7502  C  C   . GLY D 1 193 ? 85.835  118.970 72.241  1.00 37.65  ? 193 GLY D C   1 
ATOM   7503  O  O   . GLY D 1 193 ? 86.699  118.587 71.441  1.00 30.35  ? 193 GLY D O   1 
ATOM   7504  N  N   . PRO D 1 194 ? 84.534  118.776 72.016  1.00 37.18  ? 194 PRO D N   1 
ATOM   7505  C  CA  . PRO D 1 194 ? 84.088  117.935 70.888  1.00 29.70  ? 194 PRO D CA  1 
ATOM   7506  C  C   . PRO D 1 194 ? 84.236  118.638 69.546  1.00 35.55  ? 194 PRO D C   1 
ATOM   7507  O  O   . PRO D 1 194 ? 83.866  119.807 69.393  1.00 32.87  ? 194 PRO D O   1 
ATOM   7508  C  CB  . PRO D 1 194 ? 82.615  117.658 71.201  1.00 34.06  ? 194 PRO D CB  1 
ATOM   7509  C  CG  . PRO D 1 194 ? 82.199  118.758 72.164  1.00 37.79  ? 194 PRO D CG  1 
ATOM   7510  C  CD  . PRO D 1 194 ? 83.429  119.236 72.875  1.00 29.94  ? 194 PRO D CD  1 
ATOM   7511  N  N   . VAL D 1 195 ? 84.743  117.889 68.564  1.00 28.40  ? 195 VAL D N   1 
ATOM   7512  C  CA  . VAL D 1 195 ? 84.874  118.312 67.174  1.00 34.36  ? 195 VAL D CA  1 
ATOM   7513  C  C   . VAL D 1 195 ? 84.229  117.244 66.291  1.00 32.18  ? 195 VAL D C   1 
ATOM   7514  O  O   . VAL D 1 195 ? 84.631  116.071 66.337  1.00 30.58  ? 195 VAL D O   1 
ATOM   7515  C  CB  . VAL D 1 195 ? 86.348  118.511 66.773  1.00 32.81  ? 195 VAL D CB  1 
ATOM   7516  C  CG1 . VAL D 1 195 ? 86.449  118.957 65.331  1.00 33.08  ? 195 VAL D CG1 1 
ATOM   7517  C  CG2 . VAL D 1 195 ? 87.027  119.511 67.706  1.00 32.62  ? 195 VAL D CG2 1 
ATOM   7518  N  N   . LEU D 1 196 ? 83.267  117.652 65.456  1.00 29.65  ? 196 LEU D N   1 
ATOM   7519  C  CA  . LEU D 1 196 ? 82.544  116.736 64.577  1.00 24.39  ? 196 LEU D CA  1 
ATOM   7520  C  C   . LEU D 1 196 ? 83.067  116.863 63.150  1.00 29.52  ? 196 LEU D C   1 
ATOM   7521  O  O   . LEU D 1 196 ? 82.790  117.852 62.459  1.00 26.51  ? 196 LEU D O   1 
ATOM   7522  C  CB  . LEU D 1 196 ? 81.039  116.999 64.623  1.00 24.48  ? 196 LEU D CB  1 
ATOM   7523  C  CG  . LEU D 1 196 ? 80.260  116.151 63.602  1.00 29.69  ? 196 LEU D CG  1 
ATOM   7524  C  CD1 . LEU D 1 196 ? 80.494  114.670 63.831  1.00 25.98  ? 196 LEU D CD1 1 
ATOM   7525  C  CD2 . LEU D 1 196 ? 78.783  116.465 63.611  1.00 19.12  ? 196 LEU D CD2 1 
ATOM   7526  N  N   . LEU D 1 197 ? 83.791  115.840 62.696  1.00 27.37  ? 197 LEU D N   1 
ATOM   7527  C  CA  . LEU D 1 197 ? 84.230  115.765 61.303  1.00 27.38  ? 197 LEU D CA  1 
ATOM   7528  C  C   . LEU D 1 197 ? 83.100  115.147 60.483  1.00 25.81  ? 197 LEU D C   1 
ATOM   7529  O  O   . LEU D 1 197 ? 82.882  113.936 60.523  1.00 26.83  ? 197 LEU D O   1 
ATOM   7530  C  CB  . LEU D 1 197 ? 85.518  114.955 61.181  1.00 26.33  ? 197 LEU D CB  1 
ATOM   7531  C  CG  . LEU D 1 197 ? 86.718  115.506 61.961  1.00 30.16  ? 197 LEU D CG  1 
ATOM   7532  C  CD1 . LEU D 1 197 ? 87.940  114.608 61.808  1.00 28.35  ? 197 LEU D CD1 1 
ATOM   7533  C  CD2 . LEU D 1 197 ? 87.033  116.925 61.503  1.00 33.23  ? 197 LEU D CD2 1 
ATOM   7534  N  N   . ALA D 1 198 ? 82.383  115.978 59.731  1.00 25.44  ? 198 ALA D N   1 
ATOM   7535  C  CA  . ALA D 1 198 ? 81.285  115.461 58.926  1.00 29.93  ? 198 ALA D CA  1 
ATOM   7536  C  C   . ALA D 1 198 ? 81.796  114.632 57.758  1.00 29.66  ? 198 ALA D C   1 
ATOM   7537  O  O   . ALA D 1 198 ? 81.104  113.706 57.309  1.00 28.08  ? 198 ALA D O   1 
ATOM   7538  C  CB  . ALA D 1 198 ? 80.420  116.604 58.403  1.00 23.77  ? 198 ALA D CB  1 
ATOM   7539  N  N   . VAL D 1 199 ? 83.001  114.953 57.270  1.00 28.28  ? 199 VAL D N   1 
ATOM   7540  C  CA  . VAL D 1 199 ? 83.525  114.448 56.005  1.00 25.88  ? 199 VAL D CA  1 
ATOM   7541  C  C   . VAL D 1 199 ? 82.427  114.618 54.958  1.00 30.65  ? 199 VAL D C   1 
ATOM   7542  O  O   . VAL D 1 199 ? 81.795  115.681 54.883  1.00 28.78  ? 199 VAL D O   1 
ATOM   7543  C  CB  . VAL D 1 199 ? 84.019  112.993 56.138  1.00 30.40  ? 199 VAL D CB  1 
ATOM   7544  C  CG1 . VAL D 1 199 ? 84.940  112.608 54.966  1.00 25.60  ? 199 VAL D CG1 1 
ATOM   7545  C  CG2 . VAL D 1 199 ? 84.761  112.829 57.476  1.00 25.20  ? 199 VAL D CG2 1 
ATOM   7546  N  N   . ASP D 1 200 ? 82.168  113.593 54.153  1.00 29.42  ? 200 ASP D N   1 
ATOM   7547  C  CA  . ASP D 1 200 ? 81.280  113.783 53.015  1.00 29.46  ? 200 ASP D CA  1 
ATOM   7548  C  C   . ASP D 1 200 ? 79.814  113.567 53.369  1.00 27.40  ? 200 ASP D C   1 
ATOM   7549  O  O   . ASP D 1 200 ? 78.971  113.575 52.476  1.00 26.21  ? 200 ASP D O   1 
ATOM   7550  C  CB  . ASP D 1 200 ? 81.697  112.883 51.844  1.00 26.68  ? 200 ASP D CB  1 
ATOM   7551  C  CG  . ASP D 1 200 ? 82.952  113.403 51.130  1.00 32.89  ? 200 ASP D CG  1 
ATOM   7552  O  OD1 . ASP D 1 200 ? 83.655  114.262 51.696  1.00 35.37  ? 200 ASP D OD1 1 
ATOM   7553  O  OD2 . ASP D 1 200 ? 83.235  112.963 50.007  1.00 33.90  ? 200 ASP D OD2 1 
ATOM   7554  N  N   . ALA D 1 201 ? 79.488  113.390 54.645  1.00 26.93  ? 201 ALA D N   1 
ATOM   7555  C  CA  . ALA D 1 201 ? 78.079  113.414 55.011  1.00 28.86  ? 201 ALA D CA  1 
ATOM   7556  C  C   . ALA D 1 201 ? 77.482  114.798 54.791  1.00 29.67  ? 201 ALA D C   1 
ATOM   7557  O  O   . ALA D 1 201 ? 76.270  114.927 54.562  1.00 29.84  ? 201 ALA D O   1 
ATOM   7558  C  CB  . ALA D 1 201 ? 77.896  112.970 56.460  1.00 24.31  ? 201 ALA D CB  1 
ATOM   7559  N  N   . ALA D 1 202 ? 78.314  115.839 54.838  1.00 27.65  ? 202 ALA D N   1 
ATOM   7560  C  CA  . ALA D 1 202 ? 77.839  117.223 54.708  1.00 32.25  ? 202 ALA D CA  1 
ATOM   7561  C  C   . ALA D 1 202 ? 78.955  118.024 54.031  1.00 32.67  ? 202 ALA D C   1 
ATOM   7562  O  O   . ALA D 1 202 ? 79.853  118.550 54.696  1.00 31.21  ? 202 ALA D O   1 
ATOM   7563  C  CB  . ALA D 1 202 ? 77.453  117.814 56.057  1.00 28.94  ? 202 ALA D CB  1 
ATOM   7564  N  N   . TYR D 1 203 ? 78.885  118.081 52.699  1.00 34.99  ? 203 TYR D N   1 
ATOM   7565  C  CA  . TYR D 1 203 ? 79.885  118.757 51.877  1.00 37.63  ? 203 TYR D CA  1 
ATOM   7566  C  C   . TYR D 1 203 ? 80.122  120.195 52.333  1.00 41.94  ? 203 TYR D C   1 
ATOM   7567  O  O   . TYR D 1 203 ? 81.270  120.657 52.392  1.00 37.89  ? 203 TYR D O   1 
ATOM   7568  C  CB  . TYR D 1 203 ? 79.425  118.763 50.416  1.00 42.10  ? 203 TYR D CB  1 
ATOM   7569  C  CG  . TYR D 1 203 ? 79.697  117.526 49.564  1.00 41.00  ? 203 TYR D CG  1 
ATOM   7570  C  CD1 . TYR D 1 203 ? 80.710  116.629 49.870  1.00 39.65  ? 203 TYR D CD1 1 
ATOM   7571  C  CD2 . TYR D 1 203 ? 78.940  117.287 48.420  1.00 44.69  ? 203 TYR D CD2 1 
ATOM   7572  C  CE1 . TYR D 1 203 ? 80.953  115.511 49.054  1.00 36.90  ? 203 TYR D CE1 1 
ATOM   7573  C  CE2 . TYR D 1 203 ? 79.172  116.185 47.604  1.00 41.64  ? 203 TYR D CE2 1 
ATOM   7574  C  CZ  . TYR D 1 203 ? 80.177  115.302 47.922  1.00 41.33  ? 203 TYR D CZ  1 
ATOM   7575  O  OH  . TYR D 1 203 ? 80.394  114.215 47.101  1.00 40.09  ? 203 TYR D OH  1 
ATOM   7576  N  N   . THR D 1 204 ? 79.043  120.923 52.642  1.00 39.56  ? 204 THR D N   1 
ATOM   7577  C  CA  . THR D 1 204 ? 79.090  122.362 52.866  1.00 39.00  ? 204 THR D CA  1 
ATOM   7578  C  C   . THR D 1 204 ? 78.034  122.730 53.900  1.00 38.39  ? 204 THR D C   1 
ATOM   7579  O  O   . THR D 1 204 ? 77.181  121.914 54.256  1.00 36.77  ? 204 THR D O   1 
ATOM   7580  C  CB  . THR D 1 204 ? 78.831  123.154 51.569  1.00 41.62  ? 204 THR D CB  1 
ATOM   7581  O  OG1 . THR D 1 204 ? 77.482  122.934 51.132  1.00 39.22  ? 204 THR D OG1 1 
ATOM   7582  C  CG2 . THR D 1 204 ? 79.784  122.745 50.445  1.00 43.79  ? 204 THR D CG2 1 
ATOM   7583  N  N   . THR D 1 205 ? 78.087  123.987 54.363  1.00 36.91  ? 205 THR D N   1 
ATOM   7584  C  CA  . THR D 1 205 ? 77.006  124.534 55.183  1.00 37.55  ? 205 THR D CA  1 
ATOM   7585  C  C   . THR D 1 205 ? 75.645  124.379 54.502  1.00 34.64  ? 205 THR D C   1 
ATOM   7586  O  O   . THR D 1 205 ? 74.631  124.165 55.177  1.00 35.76  ? 205 THR D O   1 
ATOM   7587  C  CB  . THR D 1 205 ? 77.253  126.016 55.488  1.00 38.70  ? 205 THR D CB  1 
ATOM   7588  O  OG1 . THR D 1 205 ? 77.330  126.752 54.256  1.00 37.37  ? 205 THR D OG1 1 
ATOM   7589  C  CG2 . THR D 1 205 ? 78.545  126.212 56.281  1.00 38.07  ? 205 THR D CG2 1 
ATOM   7590  N  N   . ASP D 1 206 ? 75.600  124.511 53.168  1.00 36.78  ? 206 ASP D N   1 
ATOM   7591  C  CA  . ASP D 1 206 ? 74.337  124.404 52.434  1.00 38.11  ? 206 ASP D CA  1 
ATOM   7592  C  C   . ASP D 1 206 ? 73.716  123.023 52.599  1.00 37.96  ? 206 ASP D C   1 
ATOM   7593  O  O   . ASP D 1 206 ? 72.494  122.899 52.746  1.00 39.05  ? 206 ASP D O   1 
ATOM   7594  C  CB  . ASP D 1 206 ? 74.543  124.700 50.941  1.00 38.32  ? 206 ASP D CB  1 
ATOM   7595  C  CG  . ASP D 1 206 ? 74.216  126.164 50.554  1.00 45.20  ? 206 ASP D CG  1 
ATOM   7596  O  OD1 . ASP D 1 206 ? 73.863  126.986 51.438  1.00 42.00  ? 206 ASP D OD1 1 
ATOM   7597  O  OD2 . ASP D 1 206 ? 74.294  126.479 49.339  1.00 42.43  ? 206 ASP D OD2 1 
ATOM   7598  N  N   . HIS D 1 207 ? 74.535  121.967 52.530  1.00 38.41  ? 207 HIS D N   1 
ATOM   7599  C  CA  . HIS D 1 207 ? 74.029  120.624 52.795  1.00 34.10  ? 207 HIS D CA  1 
ATOM   7600  C  C   . HIS D 1 207 ? 73.558  120.500 54.239  1.00 34.69  ? 207 HIS D C   1 
ATOM   7601  O  O   . HIS D 1 207 ? 72.487  119.941 54.507  1.00 31.33  ? 207 HIS D O   1 
ATOM   7602  C  CB  . HIS D 1 207 ? 75.106  119.586 52.470  1.00 36.24  ? 207 HIS D CB  1 
ATOM   7603  C  CG  . HIS D 1 207 ? 75.486  119.543 51.021  1.00 43.00  ? 207 HIS D CG  1 
ATOM   7604  N  ND1 . HIS D 1 207 ? 76.452  120.366 50.480  1.00 43.15  ? 207 HIS D ND1 1 
ATOM   7605  C  CD2 . HIS D 1 207 ? 75.035  118.773 50.000  1.00 42.79  ? 207 HIS D CD2 1 
ATOM   7606  C  CE1 . HIS D 1 207 ? 76.565  120.118 49.186  1.00 44.06  ? 207 HIS D CE1 1 
ATOM   7607  N  NE2 . HIS D 1 207 ? 75.722  119.150 48.871  1.00 41.25  ? 207 HIS D NE2 1 
ATOM   7608  N  N   . TRP D 1 208 ? 74.322  121.075 55.177  1.00 36.53  ? 208 TRP D N   1 
ATOM   7609  C  CA  . TRP D 1 208 ? 73.969  121.032 56.595  1.00 31.63  ? 208 TRP D CA  1 
ATOM   7610  C  C   . TRP D 1 208 ? 72.625  121.704 56.868  1.00 33.16  ? 208 TRP D C   1 
ATOM   7611  O  O   . TRP D 1 208 ? 71.845  121.238 57.714  1.00 29.74  ? 208 TRP D O   1 
ATOM   7612  C  CB  . TRP D 1 208 ? 75.077  121.698 57.414  1.00 32.63  ? 208 TRP D CB  1 
ATOM   7613  C  CG  . TRP D 1 208 ? 74.898  121.600 58.908  1.00 33.97  ? 208 TRP D CG  1 
ATOM   7614  C  CD1 . TRP D 1 208 ? 74.272  122.502 59.716  1.00 33.23  ? 208 TRP D CD1 1 
ATOM   7615  C  CD2 . TRP D 1 208 ? 75.345  120.534 59.766  1.00 30.67  ? 208 TRP D CD2 1 
ATOM   7616  N  NE1 . TRP D 1 208 ? 74.308  122.071 61.022  1.00 28.47  ? 208 TRP D NE1 1 
ATOM   7617  C  CE2 . TRP D 1 208 ? 74.959  120.866 61.079  1.00 26.82  ? 208 TRP D CE2 1 
ATOM   7618  C  CE3 . TRP D 1 208 ? 76.036  119.334 59.548  1.00 27.11  ? 208 TRP D CE3 1 
ATOM   7619  C  CZ2 . TRP D 1 208 ? 75.241  120.043 62.180  1.00 26.55  ? 208 TRP D CZ2 1 
ATOM   7620  C  CZ3 . TRP D 1 208 ? 76.317  118.518 60.647  1.00 26.90  ? 208 TRP D CZ3 1 
ATOM   7621  C  CH2 . TRP D 1 208 ? 75.921  118.881 61.942  1.00 24.60  ? 208 TRP D CH2 1 
ATOM   7622  N  N   . ASP D 1 209 ? 72.345  122.812 56.189  1.00 30.51  ? 209 ASP D N   1 
ATOM   7623  C  CA  . ASP D 1 209 ? 71.099  123.540 56.400  1.00 37.21  ? 209 ASP D CA  1 
ATOM   7624  C  C   . ASP D 1 209 ? 69.993  123.055 55.479  1.00 35.74  ? 209 ASP D C   1 
ATOM   7625  O  O   . ASP D 1 209 ? 68.954  123.712 55.385  1.00 34.89  ? 209 ASP D O   1 
ATOM   7626  C  CB  . ASP D 1 209 ? 71.291  125.053 56.182  1.00 41.55  ? 209 ASP D CB  1 
ATOM   7627  C  CG  . ASP D 1 209 ? 72.388  125.650 57.042  1.00 39.34  ? 209 ASP D CG  1 
ATOM   7628  O  OD1 . ASP D 1 209 ? 72.461  125.321 58.246  1.00 42.05  ? 209 ASP D OD1 1 
ATOM   7629  O  OD2 . ASP D 1 209 ? 73.169  126.463 56.499  1.00 42.62  ? 209 ASP D OD2 1 
ATOM   7630  N  N   . GLU D 1 210 ? 70.228  121.960 54.755  1.00 34.45  ? 210 GLU D N   1 
ATOM   7631  C  CA  . GLU D 1 210 ? 69.200  121.309 53.951  1.00 35.71  ? 210 GLU D CA  1 
ATOM   7632  C  C   . GLU D 1 210 ? 68.710  122.232 52.832  1.00 39.98  ? 210 GLU D C   1 
ATOM   7633  O  O   . GLU D 1 210 ? 67.514  122.313 52.541  1.00 35.60  ? 210 GLU D O   1 
ATOM   7634  C  CB  . GLU D 1 210 ? 68.052  120.823 54.839  1.00 27.84  ? 210 GLU D CB  1 
ATOM   7635  C  CG  . GLU D 1 210 ? 68.541  119.847 55.904  1.00 30.65  ? 210 GLU D CG  1 
ATOM   7636  C  CD  . GLU D 1 210 ? 67.430  119.239 56.732  1.00 30.32  ? 210 GLU D CD  1 
ATOM   7637  O  OE1 . GLU D 1 210 ? 66.287  119.715 56.634  1.00 31.04  ? 210 GLU D OE1 1 
ATOM   7638  O  OE2 . GLU D 1 210 ? 67.702  118.273 57.472  1.00 28.31  ? 210 GLU D OE2 1 
ATOM   7639  N  N   . LYS D 1 211 ? 69.657  122.948 52.217  1.00 39.41  ? 211 LYS D N   1 
ATOM   7640  C  CA  . LYS D 1 211 ? 69.439  123.737 51.009  1.00 42.25  ? 211 LYS D CA  1 
ATOM   7641  C  C   . LYS D 1 211 ? 70.124  123.117 49.800  1.00 42.32  ? 211 LYS D C   1 
ATOM   7642  O  O   . LYS D 1 211 ? 70.110  123.715 48.722  1.00 46.85  ? 211 LYS D O   1 
ATOM   7643  C  CB  . LYS D 1 211 ? 69.935  125.181 51.195  1.00 39.02  ? 211 LYS D CB  1 
ATOM   7644  C  CG  . LYS D 1 211 ? 69.165  126.003 52.219  1.00 38.91  ? 211 LYS D CG  1 
ATOM   7645  C  CD  . LYS D 1 211 ? 70.098  126.603 53.272  1.00 46.27  ? 211 LYS D CD  1 
ATOM   7646  C  CE  . LYS D 1 211 ? 70.415  128.081 53.045  1.00 50.45  ? 211 LYS D CE  1 
ATOM   7647  N  NZ  . LYS D 1 211 ? 70.540  128.829 54.336  1.00 54.28  ? 211 LYS D NZ  1 
ATOM   7648  N  N   . ALA D 1 212 ? 70.728  121.936 49.955  1.00 41.74  ? 212 ALA D N   1 
ATOM   7649  C  CA  . ALA D 1 212 ? 71.417  121.267 48.860  1.00 38.70  ? 212 ALA D CA  1 
ATOM   7650  C  C   . ALA D 1 212 ? 71.518  119.793 49.181  1.00 40.78  ? 212 ALA D C   1 
ATOM   7651  O  O   . ALA D 1 212 ? 71.552  119.401 50.352  1.00 39.75  ? 212 ALA D O   1 
ATOM   7652  C  CB  . ALA D 1 212 ? 72.824  121.830 48.621  1.00 42.76  ? 212 ALA D CB  1 
ATOM   7653  N  N   . LEU D 1 213 ? 71.587  118.993 48.136  1.00 35.70  ? 213 LEU D N   1 
ATOM   7654  C  CA  . LEU D 1 213 ? 71.830  117.576 48.243  1.00 35.84  ? 213 LEU D CA  1 
ATOM   7655  C  C   . LEU D 1 213 ? 73.187  117.251 47.624  1.00 38.23  ? 213 LEU D C   1 
ATOM   7656  O  O   . LEU D 1 213 ? 73.662  117.986 46.754  1.00 34.82  ? 213 LEU D O   1 
ATOM   7657  C  CB  . LEU D 1 213 ? 70.731  116.784 47.521  1.00 37.65  ? 213 LEU D CB  1 
ATOM   7658  C  CG  . LEU D 1 213 ? 69.287  116.870 48.032  1.00 36.76  ? 213 LEU D CG  1 
ATOM   7659  C  CD1 . LEU D 1 213 ? 68.344  116.156 47.067  1.00 32.20  ? 213 LEU D CD1 1 
ATOM   7660  C  CD2 . LEU D 1 213 ? 69.144  116.311 49.450  1.00 35.90  ? 213 LEU D CD2 1 
ATOM   7661  N  N   . PRO D 1 214 ? 73.841  116.166 48.040  1.00 41.28  ? 214 PRO D N   1 
ATOM   7662  C  CA  . PRO D 1 214 ? 75.128  115.821 47.420  1.00 37.67  ? 214 PRO D CA  1 
ATOM   7663  C  C   . PRO D 1 214 ? 74.945  115.537 45.938  1.00 41.44  ? 214 PRO D C   1 
ATOM   7664  O  O   . PRO D 1 214 ? 73.970  114.905 45.524  1.00 40.12  ? 214 PRO D O   1 
ATOM   7665  C  CB  . PRO D 1 214 ? 75.594  114.575 48.185  1.00 40.83  ? 214 PRO D CB  1 
ATOM   7666  C  CG  . PRO D 1 214 ? 74.541  114.277 49.220  1.00 38.86  ? 214 PRO D CG  1 
ATOM   7667  C  CD  . PRO D 1 214 ? 73.361  115.147 48.994  1.00 34.75  ? 214 PRO D CD  1 
ATOM   7668  N  N   . GLY D 1 215 ? 75.884  116.051 45.130  1.00 39.20  ? 215 GLY D N   1 
ATOM   7669  C  CA  . GLY D 1 215 ? 75.846  115.834 43.695  1.00 44.14  ? 215 GLY D CA  1 
ATOM   7670  C  C   . GLY D 1 215 ? 76.349  114.482 43.246  1.00 43.31  ? 215 GLY D C   1 
ATOM   7671  O  O   . GLY D 1 215 ? 76.334  114.190 42.044  1.00 40.74  ? 215 GLY D O   1 
ATOM   7672  N  N   . PHE D 1 216 ? 76.824  113.675 44.192  1.00 40.21  ? 216 PHE D N   1 
ATOM   7673  C  CA  . PHE D 1 216 ? 77.119  112.266 43.986  1.00 40.61  ? 216 PHE D CA  1 
ATOM   7674  C  C   . PHE D 1 216 ? 76.683  111.549 45.253  1.00 43.75  ? 216 PHE D C   1 
ATOM   7675  O  O   . PHE D 1 216 ? 77.037  111.978 46.358  1.00 38.02  ? 216 PHE D O   1 
ATOM   7676  C  CB  . PHE D 1 216 ? 78.616  112.038 43.689  1.00 40.81  ? 216 PHE D CB  1 
ATOM   7677  C  CG  . PHE D 1 216 ? 79.020  110.586 43.648  1.00 47.41  ? 216 PHE D CG  1 
ATOM   7678  C  CD1 . PHE D 1 216 ? 79.249  109.868 44.817  1.00 52.39  ? 216 PHE D CD1 1 
ATOM   7679  C  CD2 . PHE D 1 216 ? 79.149  109.927 42.437  1.00 46.89  ? 216 PHE D CD2 1 
ATOM   7680  C  CE1 . PHE D 1 216 ? 79.600  108.525 44.771  1.00 55.90  ? 216 PHE D CE1 1 
ATOM   7681  C  CE2 . PHE D 1 216 ? 79.512  108.591 42.388  1.00 45.86  ? 216 PHE D CE2 1 
ATOM   7682  C  CZ  . PHE D 1 216 ? 79.738  107.891 43.557  1.00 48.34  ? 216 PHE D CZ  1 
ATOM   7683  N  N   . LEU D 1 217 ? 75.916  110.468 45.108  1.00 41.77  ? 217 LEU D N   1 
ATOM   7684  C  CA  . LEU D 1 217 ? 75.426  109.811 46.316  1.00 35.30  ? 217 LEU D CA  1 
ATOM   7685  C  C   . LEU D 1 217 ? 74.915  108.421 45.993  1.00 33.74  ? 217 LEU D C   1 
ATOM   7686  O  O   . LEU D 1 217 ? 74.499  108.141 44.863  1.00 32.99  ? 217 LEU D O   1 
ATOM   7687  C  CB  . LEU D 1 217 ? 74.320  110.621 46.989  1.00 31.41  ? 217 LEU D CB  1 
ATOM   7688  C  CG  . LEU D 1 217 ? 72.936  110.617 46.358  1.00 34.93  ? 217 LEU D CG  1 
ATOM   7689  C  CD1 . LEU D 1 217 ? 72.105  111.542 47.214  1.00 33.22  ? 217 LEU D CD1 1 
ATOM   7690  C  CD2 . LEU D 1 217 ? 72.943  111.075 44.890  1.00 36.44  ? 217 LEU D CD2 1 
ATOM   7691  N  N   . ALA D 1 218 ? 74.958  107.556 47.006  1.00 27.93  ? 218 ALA D N   1 
ATOM   7692  C  CA  . ALA D 1 218 ? 74.390  106.226 46.868  1.00 24.87  ? 218 ALA D CA  1 
ATOM   7693  C  C   . ALA D 1 218 ? 72.915  106.205 47.261  1.00 24.76  ? 218 ALA D C   1 
ATOM   7694  O  O   . ALA D 1 218 ? 72.117  105.561 46.580  1.00 25.02  ? 218 ALA D O   1 
ATOM   7695  C  CB  . ALA D 1 218 ? 75.184  105.226 47.710  1.00 24.85  ? 218 ALA D CB  1 
ATOM   7696  N  N   . SER D 1 219 ? 72.531  106.930 48.319  1.00 22.50  ? 219 SER D N   1 
ATOM   7697  C  CA  . SER D 1 219 ? 71.135  106.983 48.758  1.00 25.84  ? 219 SER D CA  1 
ATOM   7698  C  C   . SER D 1 219 ? 70.803  108.368 49.304  1.00 25.03  ? 219 SER D C   1 
ATOM   7699  O  O   . SER D 1 219 ? 71.316  108.760 50.360  1.00 23.20  ? 219 SER D O   1 
ATOM   7700  C  CB  . SER D 1 219 ? 70.849  105.919 49.831  1.00 23.52  ? 219 SER D CB  1 
ATOM   7701  O  OG  . SER D 1 219 ? 69.600  106.177 50.434  1.00 24.18  ? 219 SER D OG  1 
ATOM   7702  N  N   . THR D 1 220 ? 69.912  109.086 48.612  1.00 23.41  ? 220 THR D N   1 
ATOM   7703  C  CA  . THR D 1 220 ? 69.409  110.353 49.138  1.00 25.34  ? 220 THR D CA  1 
ATOM   7704  C  C   . THR D 1 220 ? 68.677  110.158 50.461  1.00 24.12  ? 220 THR D C   1 
ATOM   7705  O  O   . THR D 1 220 ? 68.797  110.986 51.381  1.00 23.63  ? 220 THR D O   1 
ATOM   7706  C  CB  . THR D 1 220 ? 68.474  111.008 48.123  1.00 27.12  ? 220 THR D CB  1 
ATOM   7707  O  OG1 . THR D 1 220 ? 69.004  110.827 46.809  1.00 30.19  ? 220 THR D OG1 1 
ATOM   7708  C  CG2 . THR D 1 220 ? 68.300  112.493 48.425  1.00 26.85  ? 220 THR D CG2 1 
ATOM   7709  N  N   . VAL D 1 221 ? 67.894  109.077 50.573  1.00 23.86  ? 221 VAL D N   1 
ATOM   7710  C  CA  . VAL D 1 221 ? 67.168  108.828 51.819  1.00 23.66  ? 221 VAL D CA  1 
ATOM   7711  C  C   . VAL D 1 221 ? 68.146  108.719 52.989  1.00 25.21  ? 221 VAL D C   1 
ATOM   7712  O  O   . VAL D 1 221 ? 67.985  109.388 54.021  1.00 22.60  ? 221 VAL D O   1 
ATOM   7713  C  CB  . VAL D 1 221 ? 66.284  107.574 51.695  1.00 21.95  ? 221 VAL D CB  1 
ATOM   7714  C  CG1 . VAL D 1 221 ? 65.725  107.192 53.047  1.00 23.31  ? 221 VAL D CG1 1 
ATOM   7715  C  CG2 . VAL D 1 221 ? 65.145  107.843 50.702  1.00 21.83  ? 221 VAL D CG2 1 
ATOM   7716  N  N   . ASP D 1 222 ? 69.189  107.886 52.841  1.00 20.94  ? 222 ASP D N   1 
ATOM   7717  C  CA  . ASP D 1 222 ? 70.171  107.769 53.918  1.00 22.99  ? 222 ASP D CA  1 
ATOM   7718  C  C   . ASP D 1 222 ? 70.898  109.092 54.133  1.00 23.70  ? 222 ASP D C   1 
ATOM   7719  O  O   . ASP D 1 222 ? 71.142  109.502 55.275  1.00 24.15  ? 222 ASP D O   1 
ATOM   7720  C  CB  . ASP D 1 222 ? 71.163  106.647 53.609  1.00 22.62  ? 222 ASP D CB  1 
ATOM   7721  C  CG  . ASP D 1 222 ? 70.499  105.259 53.617  1.00 31.87  ? 222 ASP D CG  1 
ATOM   7722  O  OD1 . ASP D 1 222 ? 69.545  105.054 54.409  1.00 27.49  ? 222 ASP D OD1 1 
ATOM   7723  O  OD2 . ASP D 1 222 ? 70.921  104.381 52.821  1.00 26.93  ? 222 ASP D OD2 1 
ATOM   7724  N  N   . ALA D 1 223 ? 71.203  109.791 53.039  1.00 22.94  ? 223 ALA D N   1 
ATOM   7725  C  CA  . ALA D 1 223 ? 72.019  110.998 53.113  1.00 21.93  ? 223 ALA D CA  1 
ATOM   7726  C  C   . ALA D 1 223 ? 71.358  112.060 53.986  1.00 21.33  ? 223 ALA D C   1 
ATOM   7727  O  O   . ALA D 1 223 ? 71.990  112.598 54.902  1.00 24.77  ? 223 ALA D O   1 
ATOM   7728  C  CB  . ALA D 1 223 ? 72.276  111.525 51.699  1.00 20.76  ? 223 ALA D CB  1 
ATOM   7729  N  N   . VAL D 1 224 ? 70.075  112.354 53.740  1.00 17.03  ? 224 VAL D N   1 
ATOM   7730  C  CA  . VAL D 1 224 ? 69.417  113.392 54.527  1.00 19.73  ? 224 VAL D CA  1 
ATOM   7731  C  C   . VAL D 1 224 ? 69.134  112.913 55.950  1.00 23.29  ? 224 VAL D C   1 
ATOM   7732  O  O   . VAL D 1 224 ? 69.156  113.715 56.893  1.00 23.64  ? 224 VAL D O   1 
ATOM   7733  C  CB  . VAL D 1 224 ? 68.131  113.885 53.839  1.00 21.43  ? 224 VAL D CB  1 
ATOM   7734  C  CG1 . VAL D 1 224 ? 68.439  114.397 52.432  1.00 20.48  ? 224 VAL D CG1 1 
ATOM   7735  C  CG2 . VAL D 1 224 ? 67.065  112.797 53.809  1.00 21.19  ? 224 VAL D CG2 1 
ATOM   7736  N  N   . ARG D 1 225 ? 68.867  111.620 56.145  1.00 19.80  ? 225 ARG D N   1 
ATOM   7737  C  CA  . ARG D 1 225 ? 68.692  111.163 57.515  1.00 19.51  ? 225 ARG D CA  1 
ATOM   7738  C  C   . ARG D 1 225 ? 70.006  111.202 58.279  1.00 23.90  ? 225 ARG D C   1 
ATOM   7739  O  O   . ARG D 1 225 ? 70.006  111.492 59.483  1.00 23.36  ? 225 ARG D O   1 
ATOM   7740  C  CB  . ARG D 1 225 ? 68.074  109.768 57.537  1.00 21.99  ? 225 ARG D CB  1 
ATOM   7741  C  CG  . ARG D 1 225 ? 66.665  109.755 56.962  1.00 23.21  ? 225 ARG D CG  1 
ATOM   7742  C  CD  . ARG D 1 225 ? 66.044  108.354 56.892  1.00 20.53  ? 225 ARG D CD  1 
ATOM   7743  N  NE  . ARG D 1 225 ? 64.743  108.405 56.231  1.00 20.41  ? 225 ARG D NE  1 
ATOM   7744  C  CZ  . ARG D 1 225 ? 63.935  107.366 56.074  1.00 21.28  ? 225 ARG D CZ  1 
ATOM   7745  N  NH1 . ARG D 1 225 ? 64.251  106.166 56.539  1.00 21.13  ? 225 ARG D NH1 1 
ATOM   7746  N  NH2 . ARG D 1 225 ? 62.783  107.533 55.433  1.00 20.86  ? 225 ARG D NH2 1 
ATOM   7747  N  N   . SER D 1 226 ? 71.126  110.934 57.593  1.00 20.26  ? 226 SER D N   1 
ATOM   7748  C  CA  . SER D 1 226 ? 72.428  111.001 58.236  1.00 21.86  ? 226 SER D CA  1 
ATOM   7749  C  C   . SER D 1 226 ? 72.810  112.438 58.579  1.00 22.37  ? 226 SER D C   1 
ATOM   7750  O  O   . SER D 1 226 ? 73.474  112.672 59.596  1.00 25.70  ? 226 SER D O   1 
ATOM   7751  C  CB  . SER D 1 226 ? 73.499  110.376 57.338  1.00 21.46  ? 226 SER D CB  1 
ATOM   7752  O  OG  . SER D 1 226 ? 73.418  108.962 57.264  1.00 21.06  ? 226 SER D OG  1 
ATOM   7753  N  N   . VAL D 1 227 ? 72.433  113.405 57.737  1.00 24.76  ? 227 VAL D N   1 
ATOM   7754  C  CA  . VAL D 1 227 ? 72.608  114.805 58.114  1.00 24.68  ? 227 VAL D CA  1 
ATOM   7755  C  C   . VAL D 1 227 ? 71.816  115.102 59.384  1.00 22.84  ? 227 VAL D C   1 
ATOM   7756  O  O   . VAL D 1 227 ? 72.331  115.711 60.328  1.00 23.57  ? 227 VAL D O   1 
ATOM   7757  C  CB  . VAL D 1 227 ? 72.206  115.743 56.963  1.00 20.87  ? 227 VAL D CB  1 
ATOM   7758  C  CG1 . VAL D 1 227 ? 72.050  117.187 57.493  1.00 22.90  ? 227 VAL D CG1 1 
ATOM   7759  C  CG2 . VAL D 1 227 ? 73.238  115.688 55.840  1.00 23.49  ? 227 VAL D CG2 1 
ATOM   7760  N  N   . ARG D 1 228 ? 70.569  114.644 59.452  1.00 20.56  ? 228 ARG D N   1 
ATOM   7761  C  CA  . ARG D 1 228 ? 69.793  114.959 60.653  1.00 27.71  ? 228 ARG D CA  1 
ATOM   7762  C  C   . ARG D 1 228 ? 70.320  114.225 61.879  1.00 26.53  ? 228 ARG D C   1 
ATOM   7763  O  O   . ARG D 1 228 ? 70.201  114.731 63.002  1.00 25.82  ? 228 ARG D O   1 
ATOM   7764  C  CB  . ARG D 1 228 ? 68.322  114.646 60.430  1.00 22.37  ? 228 ARG D CB  1 
ATOM   7765  C  CG  . ARG D 1 228 ? 67.727  115.623 59.473  1.00 23.40  ? 228 ARG D CG  1 
ATOM   7766  C  CD  . ARG D 1 228 ? 66.264  115.780 59.696  1.00 29.60  ? 228 ARG D CD  1 
ATOM   7767  N  NE  . ARG D 1 228 ? 65.750  116.802 58.800  1.00 32.42  ? 228 ARG D NE  1 
ATOM   7768  C  CZ  . ARG D 1 228 ? 64.474  117.124 58.700  1.00 30.03  ? 228 ARG D CZ  1 
ATOM   7769  N  NH1 . ARG D 1 228 ? 63.555  116.531 59.448  1.00 31.47  ? 228 ARG D NH1 1 
ATOM   7770  N  NH2 . ARG D 1 228 ? 64.113  118.069 57.840  1.00 31.37  ? 228 ARG D NH2 1 
ATOM   7771  N  N   . LYS D 1 229 ? 70.901  113.041 61.684  1.00 23.11  ? 229 LYS D N   1 
ATOM   7772  C  CA  . LYS D 1 229 ? 71.566  112.355 62.785  1.00 24.57  ? 229 LYS D CA  1 
ATOM   7773  C  C   . LYS D 1 229 ? 72.717  113.201 63.320  1.00 26.41  ? 229 LYS D C   1 
ATOM   7774  O  O   . LYS D 1 229 ? 72.936  113.282 64.541  1.00 24.50  ? 229 LYS D O   1 
ATOM   7775  C  CB  . LYS D 1 229 ? 72.061  110.983 62.311  1.00 21.25  ? 229 LYS D CB  1 
ATOM   7776  C  CG  . LYS D 1 229 ? 72.902  110.220 63.302  1.00 21.30  ? 229 LYS D CG  1 
ATOM   7777  C  CD  . LYS D 1 229 ? 73.362  108.886 62.727  1.00 22.39  ? 229 LYS D CD  1 
ATOM   7778  C  CE  . LYS D 1 229 ? 74.197  108.092 63.727  1.00 24.67  ? 229 LYS D CE  1 
ATOM   7779  N  NZ  . LYS D 1 229 ? 74.706  106.805 63.141  1.00 20.67  ? 229 LYS D NZ  1 
ATOM   7780  N  N   . LEU D 1 230 ? 73.440  113.866 62.413  1.00 23.72  ? 230 LEU D N   1 
ATOM   7781  C  CA  . LEU D 1 230 ? 74.534  114.747 62.813  1.00 26.35  ? 230 LEU D CA  1 
ATOM   7782  C  C   . LEU D 1 230 ? 74.027  116.054 63.420  1.00 25.42  ? 230 LEU D C   1 
ATOM   7783  O  O   . LEU D 1 230 ? 74.718  116.645 64.260  1.00 28.36  ? 230 LEU D O   1 
ATOM   7784  C  CB  . LEU D 1 230 ? 75.443  115.042 61.619  1.00 22.61  ? 230 LEU D CB  1 
ATOM   7785  C  CG  . LEU D 1 230 ? 76.277  113.881 61.057  1.00 28.51  ? 230 LEU D CG  1 
ATOM   7786  C  CD1 . LEU D 1 230 ? 77.243  114.399 59.992  1.00 22.02  ? 230 LEU D CD1 1 
ATOM   7787  C  CD2 . LEU D 1 230 ? 77.033  113.132 62.153  1.00 27.07  ? 230 LEU D CD2 1 
ATOM   7788  N  N   . HIS D 1 231 ? 72.849  116.538 62.998  1.00 26.28  ? 231 HIS D N   1 
ATOM   7789  C  CA  . HIS D 1 231 ? 72.233  117.667 63.697  1.00 24.62  ? 231 HIS D CA  1 
ATOM   7790  C  C   . HIS D 1 231 ? 72.052  117.341 65.170  1.00 28.63  ? 231 HIS D C   1 
ATOM   7791  O  O   . HIS D 1 231 ? 72.392  118.144 66.050  1.00 25.84  ? 231 HIS D O   1 
ATOM   7792  C  CB  . HIS D 1 231 ? 70.881  118.028 63.088  1.00 21.15  ? 231 HIS D CB  1 
ATOM   7793  C  CG  . HIS D 1 231 ? 70.966  118.619 61.720  1.00 25.12  ? 231 HIS D CG  1 
ATOM   7794  N  ND1 . HIS D 1 231 ? 69.864  118.758 60.903  1.00 25.21  ? 231 HIS D ND1 1 
ATOM   7795  C  CD2 . HIS D 1 231 ? 72.020  119.098 61.019  1.00 25.14  ? 231 HIS D CD2 1 
ATOM   7796  C  CE1 . HIS D 1 231 ? 70.235  119.306 59.760  1.00 27.19  ? 231 HIS D CE1 1 
ATOM   7797  N  NE2 . HIS D 1 231 ? 71.539  119.513 59.801  1.00 27.18  ? 231 HIS D NE2 1 
ATOM   7798  N  N   . ALA D 1 232 ? 71.506  116.159 65.452  1.00 26.90  ? 232 ALA D N   1 
ATOM   7799  C  CA  . ALA D 1 232 ? 71.245  115.781 66.832  1.00 23.29  ? 232 ALA D CA  1 
ATOM   7800  C  C   . ALA D 1 232 ? 72.542  115.655 67.609  1.00 26.99  ? 232 ALA D C   1 
ATOM   7801  O  O   . ALA D 1 232 ? 72.611  116.031 68.782  1.00 28.81  ? 232 ALA D O   1 
ATOM   7802  C  CB  . ALA D 1 232 ? 70.466  114.470 66.876  1.00 19.75  ? 232 ALA D CB  1 
ATOM   7803  N  N   . LEU D 1 233 ? 73.578  115.108 66.978  1.00 25.33  ? 233 LEU D N   1 
ATOM   7804  C  CA  . LEU D 1 233 ? 74.832  114.911 67.692  1.00 26.24  ? 233 LEU D CA  1 
ATOM   7805  C  C   . LEU D 1 233 ? 75.508  116.247 67.988  1.00 25.34  ? 233 LEU D C   1 
ATOM   7806  O  O   . LEU D 1 233 ? 76.032  116.447 69.088  1.00 30.63  ? 233 LEU D O   1 
ATOM   7807  C  CB  . LEU D 1 233 ? 75.753  113.989 66.886  1.00 22.81  ? 233 LEU D CB  1 
ATOM   7808  C  CG  . LEU D 1 233 ? 77.126  113.601 67.451  1.00 26.98  ? 233 LEU D CG  1 
ATOM   7809  C  CD1 . LEU D 1 233 ? 77.024  112.737 68.702  1.00 21.19  ? 233 LEU D CD1 1 
ATOM   7810  C  CD2 . LEU D 1 233 ? 77.917  112.870 66.384  1.00 20.13  ? 233 LEU D CD2 1 
ATOM   7811  N  N   . ALA D 1 234 ? 75.498  117.169 67.024  1.00 22.64  ? 234 ALA D N   1 
ATOM   7812  C  CA  . ALA D 1 234 ? 76.068  118.494 67.252  1.00 29.14  ? 234 ALA D CA  1 
ATOM   7813  C  C   . ALA D 1 234 ? 75.321  119.242 68.347  1.00 27.80  ? 234 ALA D C   1 
ATOM   7814  O  O   . ALA D 1 234 ? 75.947  119.883 69.198  1.00 33.44  ? 234 ALA D O   1 
ATOM   7815  C  CB  . ALA D 1 234 ? 76.065  119.313 65.956  1.00 22.20  ? 234 ALA D CB  1 
ATOM   7816  N  N   . GLU D 1 235 ? 73.985  119.195 68.324  1.00 26.90  ? 235 GLU D N   1 
ATOM   7817  C  CA  . GLU D 1 235 ? 73.190  119.852 69.364  1.00 28.97  ? 235 GLU D CA  1 
ATOM   7818  C  C   . GLU D 1 235 ? 73.470  119.256 70.738  1.00 27.52  ? 235 GLU D C   1 
ATOM   7819  O  O   . GLU D 1 235 ? 73.583  119.980 71.727  1.00 32.18  ? 235 GLU D O   1 
ATOM   7820  C  CB  . GLU D 1 235 ? 71.696  119.745 69.025  1.00 27.20  ? 235 GLU D CB  1 
ATOM   7821  C  CG  . GLU D 1 235 ? 70.781  120.635 69.883  1.00 27.58  ? 235 GLU D CG  1 
ATOM   7822  C  CD  . GLU D 1 235 ? 70.439  120.019 71.243  1.00 30.02  ? 235 GLU D CD  1 
ATOM   7823  O  OE1 . GLU D 1 235 ? 70.627  118.798 71.408  1.00 31.40  ? 235 GLU D OE1 1 
ATOM   7824  O  OE2 . GLU D 1 235 ? 69.987  120.749 72.155  1.00 29.68  ? 235 GLU D OE2 1 
ATOM   7825  N  N   . LYS D 1 236 ? 73.584  117.935 70.816  1.00 27.58  ? 236 LYS D N   1 
ATOM   7826  C  CA  . LYS D 1 236 ? 73.778  117.269 72.097  1.00 28.61  ? 236 LYS D CA  1 
ATOM   7827  C  C   . LYS D 1 236 ? 75.152  117.570 72.697  1.00 31.61  ? 236 LYS D C   1 
ATOM   7828  O  O   . LYS D 1 236 ? 75.289  117.689 73.925  1.00 28.77  ? 236 LYS D O   1 
ATOM   7829  C  CB  . LYS D 1 236 ? 73.599  115.762 71.921  1.00 29.53  ? 236 LYS D CB  1 
ATOM   7830  C  CG  . LYS D 1 236 ? 74.103  114.925 73.087  1.00 31.18  ? 236 LYS D CG  1 
ATOM   7831  C  CD  . LYS D 1 236 ? 74.023  113.458 72.742  1.00 30.56  ? 236 LYS D CD  1 
ATOM   7832  C  CE  . LYS D 1 236 ? 74.570  112.578 73.847  1.00 27.25  ? 236 LYS D CE  1 
ATOM   7833  N  NZ  . LYS D 1 236 ? 74.438  111.144 73.455  1.00 30.46  ? 236 LYS D NZ  1 
ATOM   7834  N  N   . THR D 1 237 ? 76.188  117.665 71.853  1.00 31.42  ? 237 THR D N   1 
ATOM   7835  C  CA  . THR D 1 237 ? 77.561  117.765 72.337  1.00 33.29  ? 237 THR D CA  1 
ATOM   7836  C  C   . THR D 1 237 ? 78.140  119.178 72.292  1.00 33.93  ? 237 THR D C   1 
ATOM   7837  O  O   . THR D 1 237 ? 79.122  119.439 72.997  1.00 31.95  ? 237 THR D O   1 
ATOM   7838  C  CB  . THR D 1 237 ? 78.476  116.842 71.523  1.00 31.84  ? 237 THR D CB  1 
ATOM   7839  O  OG1 . THR D 1 237 ? 78.477  117.264 70.152  1.00 31.84  ? 237 THR D OG1 1 
ATOM   7840  C  CG2 . THR D 1 237 ? 77.993  115.403 71.619  1.00 32.37  ? 237 THR D CG2 1 
ATOM   7841  N  N   . GLY D 1 238 ? 77.559  120.079 71.499  1.00 27.44  ? 238 GLY D N   1 
ATOM   7842  C  CA  . GLY D 1 238 ? 78.141  121.389 71.277  1.00 32.56  ? 238 GLY D CA  1 
ATOM   7843  C  C   . GLY D 1 238 ? 79.354  121.352 70.372  1.00 35.88  ? 238 GLY D C   1 
ATOM   7844  O  O   . GLY D 1 238 ? 80.244  122.192 70.503  1.00 35.04  ? 238 GLY D O   1 
ATOM   7845  N  N   . ALA D 1 239 ? 79.422  120.388 69.461  1.00 33.35  ? 239 ALA D N   1 
ATOM   7846  C  CA  . ALA D 1 239 ? 80.658  120.165 68.728  1.00 36.33  ? 239 ALA D CA  1 
ATOM   7847  C  C   . ALA D 1 239 ? 80.920  121.252 67.684  1.00 33.49  ? 239 ALA D C   1 
ATOM   7848  O  O   . ALA D 1 239 ? 80.003  121.807 67.070  1.00 29.43  ? 239 ALA D O   1 
ATOM   7849  C  CB  . ALA D 1 239 ? 80.639  118.788 68.064  1.00 33.08  ? 239 ALA D CB  1 
ATOM   7850  N  N   . LEU D 1 240 ? 82.191  121.563 67.506  1.00 33.32  ? 240 LEU D N   1 
ATOM   7851  C  CA  . LEU D 1 240 ? 82.618  122.278 66.321  1.00 34.78  ? 240 LEU D CA  1 
ATOM   7852  C  C   . LEU D 1 240 ? 82.404  121.381 65.115  1.00 34.09  ? 240 LEU D C   1 
ATOM   7853  O  O   . LEU D 1 240 ? 82.944  120.270 65.068  1.00 32.84  ? 240 LEU D O   1 
ATOM   7854  C  CB  . LEU D 1 240 ? 84.095  122.652 66.450  1.00 34.28  ? 240 LEU D CB  1 
ATOM   7855  C  CG  . LEU D 1 240 ? 84.762  123.270 65.223  1.00 37.57  ? 240 LEU D CG  1 
ATOM   7856  C  CD1 . LEU D 1 240 ? 84.025  124.530 64.785  1.00 32.10  ? 240 LEU D CD1 1 
ATOM   7857  C  CD2 . LEU D 1 240 ? 86.227  123.571 65.529  1.00 38.50  ? 240 LEU D CD2 1 
ATOM   7858  N  N   . VAL D 1 241 ? 81.629  121.856 64.137  1.00 33.50  ? 241 VAL D N   1 
ATOM   7859  C  CA  . VAL D 1 241 ? 81.301  121.078 62.945  1.00 29.40  ? 241 VAL D CA  1 
ATOM   7860  C  C   . VAL D 1 241 ? 82.249  121.448 61.806  1.00 35.90  ? 241 VAL D C   1 
ATOM   7861  O  O   . VAL D 1 241 ? 82.356  122.622 61.428  1.00 35.50  ? 241 VAL D O   1 
ATOM   7862  C  CB  . VAL D 1 241 ? 79.835  121.290 62.532  1.00 33.95  ? 241 VAL D CB  1 
ATOM   7863  C  CG1 . VAL D 1 241 ? 79.485  120.409 61.335  1.00 30.65  ? 241 VAL D CG1 1 
ATOM   7864  C  CG2 . VAL D 1 241 ? 78.897  121.000 63.719  1.00 28.59  ? 241 VAL D CG2 1 
ATOM   7865  N  N   . VAL D 1 242 ? 82.910  120.445 61.233  1.00 31.14  ? 242 VAL D N   1 
ATOM   7866  C  CA  . VAL D 1 242 ? 83.834  120.632 60.114  1.00 35.40  ? 242 VAL D CA  1 
ATOM   7867  C  C   . VAL D 1 242 ? 83.235  119.944 58.890  1.00 33.87  ? 242 VAL D C   1 
ATOM   7868  O  O   . VAL D 1 242 ? 83.152  118.713 58.847  1.00 34.13  ? 242 VAL D O   1 
ATOM   7869  C  CB  . VAL D 1 242 ? 85.231  120.072 60.431  1.00 34.11  ? 242 VAL D CB  1 
ATOM   7870  C  CG1 . VAL D 1 242 ? 86.174  120.279 59.259  1.00 35.50  ? 242 VAL D CG1 1 
ATOM   7871  C  CG2 . VAL D 1 242 ? 85.794  120.710 61.691  1.00 34.27  ? 242 VAL D CG2 1 
ATOM   7872  N  N   . TYR D 1 243 ? 82.841  120.723 57.885  1.00 34.73  ? 243 TYR D N   1 
ATOM   7873  C  CA  . TYR D 1 243 ? 82.264  120.175 56.664  1.00 33.41  ? 243 TYR D CA  1 
ATOM   7874  C  C   . TYR D 1 243 ? 83.360  119.634 55.742  1.00 40.60  ? 243 TYR D C   1 
ATOM   7875  O  O   . TYR D 1 243 ? 84.533  120.015 55.830  1.00 39.63  ? 243 TYR D O   1 
ATOM   7876  C  CB  . TYR D 1 243 ? 81.424  121.238 55.953  1.00 36.81  ? 243 TYR D CB  1 
ATOM   7877  C  CG  . TYR D 1 243 ? 80.586  122.052 56.924  1.00 38.50  ? 243 TYR D CG  1 
ATOM   7878  C  CD1 . TYR D 1 243 ? 79.358  121.580 57.389  1.00 34.98  ? 243 TYR D CD1 1 
ATOM   7879  C  CD2 . TYR D 1 243 ? 81.047  123.274 57.414  1.00 41.39  ? 243 TYR D CD2 1 
ATOM   7880  C  CE1 . TYR D 1 243 ? 78.593  122.323 58.296  1.00 36.98  ? 243 TYR D CE1 1 
ATOM   7881  C  CE2 . TYR D 1 243 ? 80.295  124.020 58.327  1.00 39.41  ? 243 TYR D CE2 1 
ATOM   7882  C  CZ  . TYR D 1 243 ? 79.074  123.547 58.760  1.00 42.24  ? 243 TYR D CZ  1 
ATOM   7883  O  OH  . TYR D 1 243 ? 78.347  124.304 59.657  1.00 39.81  ? 243 TYR D OH  1 
ATOM   7884  N  N   . GLY D 1 244 ? 82.961  118.732 54.838  1.00 36.80  ? 244 GLY D N   1 
ATOM   7885  C  CA  . GLY D 1 244 ? 83.937  117.908 54.145  1.00 33.29  ? 244 GLY D CA  1 
ATOM   7886  C  C   . GLY D 1 244 ? 84.608  118.558 52.953  1.00 42.23  ? 244 GLY D C   1 
ATOM   7887  O  O   . GLY D 1 244 ? 85.763  118.239 52.646  1.00 37.67  ? 244 GLY D O   1 
ATOM   7888  N  N   . HIS D 1 245 ? 83.905  119.438 52.247  1.00 35.99  ? 245 HIS D N   1 
ATOM   7889  C  CA  . HIS D 1 245 ? 84.419  120.050 51.029  1.00 40.05  ? 245 HIS D CA  1 
ATOM   7890  C  C   . HIS D 1 245 ? 83.858  121.464 50.913  1.00 44.22  ? 245 HIS D C   1 
ATOM   7891  O  O   . HIS D 1 245 ? 83.218  121.835 49.932  1.00 41.97  ? 245 HIS D O   1 
ATOM   7892  C  CB  . HIS D 1 245 ? 84.054  119.224 49.797  1.00 40.92  ? 245 HIS D CB  1 
ATOM   7893  C  CG  . HIS D 1 245 ? 84.768  117.916 49.705  1.00 40.70  ? 245 HIS D CG  1 
ATOM   7894  N  ND1 . HIS D 1 245 ? 86.143  117.820 49.652  1.00 43.25  ? 245 HIS D ND1 1 
ATOM   7895  C  CD2 . HIS D 1 245 ? 84.298  116.647 49.648  1.00 38.58  ? 245 HIS D CD2 1 
ATOM   7896  C  CE1 . HIS D 1 245 ? 86.489  116.547 49.557  1.00 40.41  ? 245 HIS D CE1 1 
ATOM   7897  N  NE2 . HIS D 1 245 ? 85.388  115.814 49.561  1.00 39.40  ? 245 HIS D NE2 1 
ATOM   7898  N  N   . ASP D 1 246 ? 84.081  122.288 51.928  1.00 40.42  ? 246 ASP D N   1 
ATOM   7899  C  CA  . ASP D 1 246 ? 83.470  123.609 51.914  1.00 44.35  ? 246 ASP D CA  1 
ATOM   7900  C  C   . ASP D 1 246 ? 84.542  124.654 51.658  1.00 47.71  ? 246 ASP D C   1 
ATOM   7901  O  O   . ASP D 1 246 ? 85.266  125.043 52.592  1.00 40.00  ? 246 ASP D O   1 
ATOM   7902  C  CB  . ASP D 1 246 ? 82.738  123.901 53.223  1.00 39.94  ? 246 ASP D CB  1 
ATOM   7903  C  CG  . ASP D 1 246 ? 81.856  125.121 53.113  1.00 42.66  ? 246 ASP D CG  1 
ATOM   7904  O  OD1 . ASP D 1 246 ? 82.239  126.074 52.395  1.00 47.45  ? 246 ASP D OD1 1 
ATOM   7905  O  OD2 . ASP D 1 246 ? 80.779  125.139 53.730  1.00 41.39  ? 246 ASP D OD2 1 
ATOM   7906  N  N   . PRO D 1 247 ? 84.653  125.167 50.426  1.00 46.66  ? 247 PRO D N   1 
ATOM   7907  C  CA  . PRO D 1 247 ? 85.715  126.137 50.114  1.00 46.32  ? 247 PRO D CA  1 
ATOM   7908  C  C   . PRO D 1 247 ? 85.508  127.495 50.760  1.00 47.44  ? 247 PRO D C   1 
ATOM   7909  O  O   . PRO D 1 247 ? 86.427  128.322 50.706  1.00 51.35  ? 247 PRO D O   1 
ATOM   7910  C  CB  . PRO D 1 247 ? 85.661  126.257 48.584  1.00 49.53  ? 247 PRO D CB  1 
ATOM   7911  C  CG  . PRO D 1 247 ? 84.382  125.569 48.145  1.00 48.39  ? 247 PRO D CG  1 
ATOM   7912  C  CD  . PRO D 1 247 ? 83.670  125.019 49.338  1.00 44.44  ? 247 PRO D CD  1 
ATOM   7913  N  N   . GLU D 1 248 ? 84.338  127.763 51.346  1.00 46.97  ? 248 GLU D N   1 
ATOM   7914  C  CA  . GLU D 1 248 ? 84.129  129.001 52.089  1.00 50.13  ? 248 GLU D CA  1 
ATOM   7915  C  C   . GLU D 1 248 ? 84.400  128.839 53.580  1.00 49.15  ? 248 GLU D C   1 
ATOM   7916  O  O   . GLU D 1 248 ? 84.895  129.771 54.221  1.00 50.73  ? 248 GLU D O   1 
ATOM   7917  C  CB  . GLU D 1 248 ? 82.699  129.509 51.894  1.00 52.46  ? 248 GLU D CB  1 
ATOM   7918  C  CG  . GLU D 1 248 ? 82.571  130.692 50.952  1.00 62.36  ? 248 GLU D CG  1 
ATOM   7919  C  CD  . GLU D 1 248 ? 81.339  130.605 50.064  1.00 77.37  ? 248 GLU D CD  1 
ATOM   7920  O  OE1 . GLU D 1 248 ? 81.384  131.135 48.933  1.00 83.06  ? 248 GLU D OE1 1 
ATOM   7921  O  OE2 . GLU D 1 248 ? 80.320  130.023 50.503  1.00 74.09  ? 248 GLU D OE2 1 
ATOM   7922  N  N   . ALA D 1 249 ? 84.079  127.679 54.152  1.00 41.37  ? 249 ALA D N   1 
ATOM   7923  C  CA  . ALA D 1 249 ? 84.264  127.471 55.582  1.00 44.46  ? 249 ALA D CA  1 
ATOM   7924  C  C   . ALA D 1 249 ? 85.639  126.913 55.925  1.00 44.70  ? 249 ALA D C   1 
ATOM   7925  O  O   . ALA D 1 249 ? 86.130  127.137 57.039  1.00 42.77  ? 249 ALA D O   1 
ATOM   7926  C  CB  . ALA D 1 249 ? 83.173  126.540 56.122  1.00 44.02  ? 249 ALA D CB  1 
ATOM   7927  N  N   . TRP D 1 250 ? 86.267  126.193 54.998  1.00 43.87  ? 250 TRP D N   1 
ATOM   7928  C  CA  . TRP D 1 250 ? 87.569  125.581 55.261  1.00 43.40  ? 250 TRP D CA  1 
ATOM   7929  C  C   . TRP D 1 250 ? 88.620  126.574 55.751  1.00 45.27  ? 250 TRP D C   1 
ATOM   7930  O  O   . TRP D 1 250 ? 89.270  126.285 56.769  1.00 42.07  ? 250 TRP D O   1 
ATOM   7931  C  CB  . TRP D 1 250 ? 88.024  124.839 53.997  1.00 36.95  ? 250 TRP D CB  1 
ATOM   7932  C  CG  . TRP D 1 250 ? 89.296  124.046 54.135  1.00 43.39  ? 250 TRP D CG  1 
ATOM   7933  C  CD1 . TRP D 1 250 ? 90.463  124.225 53.429  1.00 43.38  ? 250 TRP D CD1 1 
ATOM   7934  C  CD2 . TRP D 1 250 ? 89.521  122.922 54.997  1.00 40.35  ? 250 TRP D CD2 1 
ATOM   7935  N  NE1 . TRP D 1 250 ? 91.399  123.284 53.811  1.00 40.00  ? 250 TRP D NE1 1 
ATOM   7936  C  CE2 . TRP D 1 250 ? 90.847  122.476 54.772  1.00 42.15  ? 250 TRP D CE2 1 
ATOM   7937  C  CE3 . TRP D 1 250 ? 88.733  122.250 55.940  1.00 39.37  ? 250 TRP D CE3 1 
ATOM   7938  C  CZ2 . TRP D 1 250 ? 91.402  121.388 55.462  1.00 39.83  ? 250 TRP D CZ2 1 
ATOM   7939  C  CZ3 . TRP D 1 250 ? 89.283  121.178 56.623  1.00 41.63  ? 250 TRP D CZ3 1 
ATOM   7940  C  CH2 . TRP D 1 250 ? 90.612  120.763 56.386  1.00 39.91  ? 250 TRP D CH2 1 
ATOM   7941  N  N   . PRO D 1 251 ? 88.830  127.741 55.115  1.00 44.57  ? 251 PRO D N   1 
ATOM   7942  C  CA  . PRO D 1 251 ? 89.855  128.674 55.622  1.00 47.40  ? 251 PRO D CA  1 
ATOM   7943  C  C   . PRO D 1 251 ? 89.568  129.198 57.016  1.00 47.67  ? 251 PRO D C   1 
ATOM   7944  O  O   . PRO D 1 251 ? 90.499  129.671 57.681  1.00 45.99  ? 251 PRO D O   1 
ATOM   7945  C  CB  . PRO D 1 251 ? 89.842  129.815 54.592  1.00 41.32  ? 251 PRO D CB  1 
ATOM   7946  C  CG  . PRO D 1 251 ? 89.198  129.257 53.396  1.00 47.07  ? 251 PRO D CG  1 
ATOM   7947  C  CD  . PRO D 1 251 ? 88.191  128.273 53.898  1.00 47.98  ? 251 PRO D CD  1 
ATOM   7948  N  N   . THR D 1 252 ? 88.317  129.134 57.479  1.00 43.25  ? 252 THR D N   1 
ATOM   7949  C  CA  . THR D 1 252 ? 87.958  129.596 58.814  1.00 43.37  ? 252 THR D CA  1 
ATOM   7950  C  C   . THR D 1 252 ? 88.371  128.627 59.910  1.00 46.74  ? 252 THR D C   1 
ATOM   7951  O  O   . THR D 1 252 ? 88.155  128.934 61.085  1.00 43.81  ? 252 THR D O   1 
ATOM   7952  C  CB  . THR D 1 252 ? 86.452  129.830 58.909  1.00 45.87  ? 252 THR D CB  1 
ATOM   7953  O  OG1 . THR D 1 252 ? 85.772  128.564 58.930  1.00 46.35  ? 252 THR D OG1 1 
ATOM   7954  C  CG2 . THR D 1 252 ? 85.973  130.634 57.717  1.00 43.85  ? 252 THR D CG2 1 
ATOM   7955  N  N   . PHE D 1 253 ? 88.937  127.469 59.566  1.00 46.38  ? 253 PHE D N   1 
ATOM   7956  C  CA  . PHE D 1 253 ? 89.427  126.528 60.560  1.00 46.01  ? 253 PHE D CA  1 
ATOM   7957  C  C   . PHE D 1 253 ? 90.946  126.617 60.680  1.00 46.44  ? 253 PHE D C   1 
ATOM   7958  O  O   . PHE D 1 253 ? 91.635  127.150 59.808  1.00 47.72  ? 253 PHE D O   1 
ATOM   7959  C  CB  . PHE D 1 253 ? 89.023  125.096 60.208  1.00 44.33  ? 253 PHE D CB  1 
ATOM   7960  C  CG  . PHE D 1 253 ? 87.539  124.879 60.129  1.00 44.86  ? 253 PHE D CG  1 
ATOM   7961  C  CD1 . PHE D 1 253 ? 86.763  124.891 61.278  1.00 41.32  ? 253 PHE D CD1 1 
ATOM   7962  C  CD2 . PHE D 1 253 ? 86.924  124.638 58.905  1.00 41.97  ? 253 PHE D CD2 1 
ATOM   7963  C  CE1 . PHE D 1 253 ? 85.393  124.685 61.214  1.00 42.91  ? 253 PHE D CE1 1 
ATOM   7964  C  CE2 . PHE D 1 253 ? 85.555  124.439 58.830  1.00 43.96  ? 253 PHE D CE2 1 
ATOM   7965  C  CZ  . PHE D 1 253 ? 84.785  124.463 59.991  1.00 40.78  ? 253 PHE D CZ  1 
ATOM   7966  N  N   . ARG D 1 254 ? 91.461  126.063 61.777  1.00 48.40  ? 254 ARG D N   1 
ATOM   7967  C  CA  . ARG D 1 254 ? 92.899  125.999 62.021  1.00 47.75  ? 254 ARG D CA  1 
ATOM   7968  C  C   . ARG D 1 254 ? 93.508  124.848 61.220  1.00 47.43  ? 254 ARG D C   1 
ATOM   7969  O  O   . ARG D 1 254 ? 93.176  123.678 61.451  1.00 46.04  ? 254 ARG D O   1 
ATOM   7970  C  CB  . ARG D 1 254 ? 93.161  125.845 63.522  1.00 46.42  ? 254 ARG D CB  1 
ATOM   7971  C  CG  . ARG D 1 254 ? 92.163  126.618 64.411  1.00 49.46  ? 254 ARG D CG  1 
ATOM   7972  C  CD  . ARG D 1 254 ? 92.502  126.551 65.911  1.00 47.37  ? 254 ARG D CD  1 
ATOM   7973  N  NE  . ARG D 1 254 ? 93.935  126.596 66.195  1.00 54.39  ? 254 ARG D NE  1 
ATOM   7974  C  CZ  . ARG D 1 254 ? 94.751  127.614 65.925  1.00 63.89  ? 254 ARG D CZ  1 
ATOM   7975  N  NH1 . ARG D 1 254 ? 94.297  128.764 65.447  1.00 56.21  ? 254 ARG D NH1 1 
ATOM   7976  N  NH2 . ARG D 1 254 ? 96.057  127.477 66.152  1.00 52.01  ? 254 ARG D NH2 1 
ATOM   7977  N  N   . LEU D 1 255 ? 94.410  125.178 60.295  1.00 46.72  ? 255 LEU D N   1 
ATOM   7978  C  CA  . LEU D 1 255 ? 94.861  124.233 59.271  1.00 44.72  ? 255 LEU D CA  1 
ATOM   7979  C  C   . LEU D 1 255 ? 96.314  123.723 59.434  1.00 44.51  ? 255 LEU D C   1 
ATOM   7980  O  O   . LEU D 1 255 ? 97.079  124.226 60.253  1.00 48.14  ? 255 LEU D O   1 
ATOM   7981  C  CB  . LEU D 1 255 ? 94.697  124.882 57.890  1.00 44.34  ? 255 LEU D CB  1 
ATOM   7982  C  CG  . LEU D 1 255 ? 93.254  125.083 57.399  1.00 49.59  ? 255 LEU D CG  1 
ATOM   7983  C  CD1 . LEU D 1 255 ? 93.200  125.398 55.901  1.00 40.43  ? 255 LEU D CD1 1 
ATOM   7984  C  CD2 . LEU D 1 255 ? 92.365  123.870 57.717  1.00 45.90  ? 255 LEU D CD2 1 
ATOM   7985  N  N   . PRO E 1 4   ? 69.700  117.247 88.982  1.00 39.36  ? 4   PRO E N   1 
ATOM   7986  C  CA  . PRO E 1 4   ? 68.559  116.659 88.266  1.00 37.77  ? 4   PRO E CA  1 
ATOM   7987  C  C   . PRO E 1 4   ? 67.479  116.143 89.200  1.00 34.73  ? 4   PRO E C   1 
ATOM   7988  O  O   . PRO E 1 4   ? 67.795  115.529 90.216  1.00 32.03  ? 4   PRO E O   1 
ATOM   7989  C  CB  . PRO E 1 4   ? 69.165  115.476 87.488  1.00 35.31  ? 4   PRO E CB  1 
ATOM   7990  C  CG  . PRO E 1 4   ? 70.622  115.628 87.550  1.00 41.28  ? 4   PRO E CG  1 
ATOM   7991  C  CD  . PRO E 1 4   ? 70.975  116.573 88.660  1.00 44.01  ? 4   PRO E CD  1 
ATOM   7992  N  N   . ARG E 1 5   ? 66.224  116.367 88.828  1.00 31.04  ? 5   ARG E N   1 
ATOM   7993  C  CA  . ARG E 1 5   ? 65.078  115.841 89.557  1.00 37.92  ? 5   ARG E CA  1 
ATOM   7994  C  C   . ARG E 1 5   ? 64.051  115.311 88.569  1.00 35.01  ? 5   ARG E C   1 
ATOM   7995  O  O   . ARG E 1 5   ? 63.953  115.778 87.431  1.00 35.30  ? 5   ARG E O   1 
ATOM   7996  C  CB  . ARG E 1 5   ? 64.396  116.904 90.429  1.00 36.93  ? 5   ARG E CB  1 
ATOM   7997  C  CG  . ARG E 1 5   ? 65.246  117.444 91.536  1.00 41.93  ? 5   ARG E CG  1 
ATOM   7998  C  CD  . ARG E 1 5   ? 64.443  118.377 92.401  1.00 44.20  ? 5   ARG E CD  1 
ATOM   7999  N  NE  . ARG E 1 5   ? 65.255  119.482 92.893  1.00 48.91  ? 5   ARG E NE  1 
ATOM   8000  C  CZ  . ARG E 1 5   ? 64.857  120.333 93.829  1.00 54.03  ? 5   ARG E CZ  1 
ATOM   8001  N  NH1 . ARG E 1 5   ? 63.660  120.237 94.387  1.00 47.61  ? 5   ARG E NH1 1 
ATOM   8002  N  NH2 . ARG E 1 5   ? 65.677  121.307 94.213  1.00 54.85  ? 5   ARG E NH2 1 
ATOM   8003  N  N   . LEU E 1 6   ? 63.247  114.369 89.047  1.00 33.62  ? 6   LEU E N   1 
ATOM   8004  C  CA  . LEU E 1 6   ? 62.157  113.782 88.284  1.00 36.25  ? 6   LEU E CA  1 
ATOM   8005  C  C   . LEU E 1 6   ? 60.844  114.133 88.964  1.00 37.87  ? 6   LEU E C   1 
ATOM   8006  O  O   . LEU E 1 6   ? 60.643  113.793 90.136  1.00 39.20  ? 6   LEU E O   1 
ATOM   8007  C  CB  . LEU E 1 6   ? 62.318  112.262 88.188  1.00 34.22  ? 6   LEU E CB  1 
ATOM   8008  C  CG  . LEU E 1 6   ? 61.069  111.437 87.889  1.00 32.82  ? 6   LEU E CG  1 
ATOM   8009  C  CD1 . LEU E 1 6   ? 60.641  111.655 86.446  1.00 31.91  ? 6   LEU E CD1 1 
ATOM   8010  C  CD2 . LEU E 1 6   ? 61.328  109.965 88.172  1.00 36.04  ? 6   LEU E CD2 1 
ATOM   8011  N  N   . TYR E 1 7   ? 59.952  114.794 88.226  1.00 33.15  ? 7   TYR E N   1 
ATOM   8012  C  CA  . TYR E 1 7   ? 58.595  115.080 88.682  1.00 36.92  ? 7   TYR E CA  1 
ATOM   8013  C  C   . TYR E 1 7   ? 57.599  114.243 87.883  1.00 36.86  ? 7   TYR E C   1 
ATOM   8014  O  O   . TYR E 1 7   ? 57.575  114.313 86.648  1.00 35.78  ? 7   TYR E O   1 
ATOM   8015  C  CB  . TYR E 1 7   ? 58.257  116.571 88.529  1.00 34.04  ? 7   TYR E CB  1 
ATOM   8016  C  CG  . TYR E 1 7   ? 59.123  117.535 89.323  1.00 37.54  ? 7   TYR E CG  1 
ATOM   8017  C  CD1 . TYR E 1 7   ? 60.344  117.980 88.825  1.00 38.36  ? 7   TYR E CD1 1 
ATOM   8018  C  CD2 . TYR E 1 7   ? 58.706  118.024 90.559  1.00 43.93  ? 7   TYR E CD2 1 
ATOM   8019  C  CE1 . TYR E 1 7   ? 61.137  118.872 89.541  1.00 40.21  ? 7   TYR E CE1 1 
ATOM   8020  C  CE2 . TYR E 1 7   ? 59.490  118.924 91.283  1.00 45.01  ? 7   TYR E CE2 1 
ATOM   8021  C  CZ  . TYR E 1 7   ? 60.696  119.342 90.768  1.00 43.67  ? 7   TYR E CZ  1 
ATOM   8022  O  OH  . TYR E 1 7   ? 61.463  120.217 91.486  1.00 41.42  ? 7   TYR E OH  1 
ATOM   8023  N  N   . MET E 1 8   ? 56.759  113.485 88.584  1.00 37.81  ? 8   MET E N   1 
ATOM   8024  C  CA  . MET E 1 8   ? 55.731  112.648 87.966  1.00 35.32  ? 8   MET E CA  1 
ATOM   8025  C  C   . MET E 1 8   ? 54.398  113.394 88.006  1.00 39.46  ? 8   MET E C   1 
ATOM   8026  O  O   . MET E 1 8   ? 53.717  113.414 89.033  1.00 43.47  ? 8   MET E O   1 
ATOM   8027  C  CB  . MET E 1 8   ? 55.627  111.307 88.685  1.00 33.44  ? 8   MET E CB  1 
ATOM   8028  C  CG  . MET E 1 8   ? 56.982  110.664 88.974  1.00 36.63  ? 8   MET E CG  1 
ATOM   8029  S  SD  . MET E 1 8   ? 57.097  108.858 88.875  1.00 40.91  ? 8   MET E SD  1 
ATOM   8030  C  CE  . MET E 1 8   ? 55.623  108.355 89.722  1.00 40.55  ? 8   MET E CE  1 
ATOM   8031  N  N   . PHE E 1 9   ? 54.022  113.990 86.887  1.00 37.66  ? 9   PHE E N   1 
ATOM   8032  C  CA  . PHE E 1 9   ? 52.702  114.647 86.800  1.00 35.62  ? 9   PHE E CA  1 
ATOM   8033  C  C   . PHE E 1 9   ? 51.683  113.625 86.283  1.00 39.56  ? 9   PHE E C   1 
ATOM   8034  O  O   . PHE E 1 9   ? 52.069  112.505 85.936  1.00 37.34  ? 9   PHE E O   1 
ATOM   8035  C  CB  . PHE E 1 9   ? 52.772  115.870 85.893  1.00 32.16  ? 9   PHE E CB  1 
ATOM   8036  C  CG  . PHE E 1 9   ? 53.640  117.008 86.359  1.00 40.51  ? 9   PHE E CG  1 
ATOM   8037  C  CD1 . PHE E 1 9   ? 55.003  117.009 86.117  1.00 38.86  ? 9   PHE E CD1 1 
ATOM   8038  C  CD2 . PHE E 1 9   ? 53.084  118.104 86.997  1.00 42.20  ? 9   PHE E CD2 1 
ATOM   8039  C  CE1 . PHE E 1 9   ? 55.793  118.069 86.527  1.00 41.17  ? 9   PHE E CE1 1 
ATOM   8040  C  CE2 . PHE E 1 9   ? 53.876  119.162 87.409  1.00 40.88  ? 9   PHE E CE2 1 
ATOM   8041  C  CZ  . PHE E 1 9   ? 55.230  119.142 87.175  1.00 45.51  ? 9   PHE E CZ  1 
ATOM   8042  N  N   . GLN E 1 10  ? 50.434  114.062 86.104  1.00 39.15  ? 10  GLN E N   1 
ATOM   8043  C  CA  . GLN E 1 10  ? 49.374  113.192 85.536  1.00 38.07  ? 10  GLN E CA  1 
ATOM   8044  C  C   . GLN E 1 10  ? 48.339  114.086 84.847  1.00 40.07  ? 10  GLN E C   1 
ATOM   8045  O  O   . GLN E 1 10  ? 47.926  115.083 85.447  1.00 37.05  ? 10  GLN E O   1 
ATOM   8046  C  CB  . GLN E 1 10  ? 48.789  112.290 86.625  1.00 41.00  ? 10  GLN E CB  1 
ATOM   8047  C  CG  . GLN E 1 10  ? 47.285  112.373 86.810  1.00 37.44  ? 10  GLN E CG  1 
ATOM   8048  C  CD  . GLN E 1 10  ? 46.834  111.419 87.886  1.00 37.04  ? 10  GLN E CD  1 
ATOM   8049  O  OE1 . GLN E 1 10  ? 47.442  111.323 88.948  1.00 41.39  ? 10  GLN E OE1 1 
ATOM   8050  N  NE2 . GLN E 1 10  ? 45.763  110.693 87.615  1.00 36.82  ? 10  GLN E NE2 1 
ATOM   8051  N  N   . THR E 1 11  ? 47.966  113.753 83.616  1.00 39.63  ? 11  THR E N   1 
ATOM   8052  C  CA  . THR E 1 11  ? 46.982  114.555 82.848  1.00 41.03  ? 11  THR E CA  1 
ATOM   8053  C  C   . THR E 1 11  ? 45.582  113.979 83.103  1.00 43.55  ? 11  THR E C   1 
ATOM   8054  O  O   . THR E 1 11  ? 44.837  113.717 82.154  1.00 44.25  ? 11  THR E O   1 
ATOM   8055  C  CB  . THR E 1 11  ? 47.412  114.633 81.383  1.00 38.93  ? 11  THR E CB  1 
ATOM   8056  O  OG1 . THR E 1 11  ? 46.612  115.594 80.700  1.00 47.34  ? 11  THR E OG1 1 
ATOM   8057  C  CG2 . THR E 1 11  ? 47.301  113.291 80.708  1.00 34.37  ? 11  THR E CG2 1 
ATOM   8058  N  N   . GLY E 1 12  ? 45.241  113.816 84.372  1.00 41.24  ? 12  GLY E N   1 
ATOM   8059  C  CA  . GLY E 1 12  ? 43.923  113.287 84.724  1.00 43.24  ? 12  GLY E CA  1 
ATOM   8060  C  C   . GLY E 1 12  ? 43.859  111.788 84.587  1.00 43.73  ? 12  GLY E C   1 
ATOM   8061  O  O   . GLY E 1 12  ? 44.844  111.122 84.926  1.00 42.17  ? 12  GLY E O   1 
ATOM   8062  N  N   . THR E 1 13  ? 42.740  111.287 84.079  1.00 41.83  ? 13  THR E N   1 
ATOM   8063  C  CA  . THR E 1 13  ? 42.559  109.824 84.019  1.00 40.61  ? 13  THR E CA  1 
ATOM   8064  C  C   . THR E 1 13  ? 41.845  109.390 82.744  1.00 39.98  ? 13  THR E C   1 
ATOM   8065  O  O   . THR E 1 13  ? 41.304  110.256 82.051  1.00 40.76  ? 13  THR E O   1 
ATOM   8066  C  CB  . THR E 1 13  ? 41.741  109.322 85.217  1.00 40.26  ? 13  THR E CB  1 
ATOM   8067  O  OG1 . THR E 1 13  ? 40.517  110.055 85.268  1.00 43.85  ? 13  THR E OG1 1 
ATOM   8068  C  CG2 . THR E 1 13  ? 42.479  109.420 86.533  1.00 39.65  ? 13  THR E CG2 1 
ATOM   8069  N  N   . LEU E 1 14  ? 41.877  108.097 82.450  1.00 39.34  ? 14  LEU E N   1 
ATOM   8070  C  CA  . LEU E 1 14  ? 41.133  107.514 81.341  1.00 43.68  ? 14  LEU E CA  1 
ATOM   8071  C  C   . LEU E 1 14  ? 40.082  106.565 81.895  1.00 41.64  ? 14  LEU E C   1 
ATOM   8072  O  O   . LEU E 1 14  ? 40.360  105.791 82.814  1.00 44.00  ? 14  LEU E O   1 
ATOM   8073  C  CB  . LEU E 1 14  ? 42.063  106.745 80.366  1.00 41.31  ? 14  LEU E CB  1 
ATOM   8074  C  CG  . LEU E 1 14  ? 43.049  107.548 79.522  1.00 38.72  ? 14  LEU E CG  1 
ATOM   8075  C  CD1 . LEU E 1 14  ? 43.638  106.704 78.415  1.00 38.57  ? 14  LEU E CD1 1 
ATOM   8076  C  CD2 . LEU E 1 14  ? 42.367  108.771 78.922  1.00 42.86  ? 14  LEU E CD2 1 
ATOM   8077  N  N   . LYS E 1 15  ? 38.875  106.621 81.343  1.00 41.70  ? 15  LYS E N   1 
ATOM   8078  C  CA  . LYS E 1 15  ? 37.819  105.689 81.708  1.00 48.07  ? 15  LYS E CA  1 
ATOM   8079  C  C   . LYS E 1 15  ? 37.646  104.699 80.568  1.00 46.62  ? 15  LYS E C   1 
ATOM   8080  O  O   . LYS E 1 15  ? 37.454  105.104 79.418  1.00 48.94  ? 15  LYS E O   1 
ATOM   8081  C  CB  . LYS E 1 15  ? 36.503  106.418 82.006  1.00 48.67  ? 15  LYS E CB  1 
ATOM   8082  C  CG  . LYS E 1 15  ? 36.418  106.973 83.438  1.00 56.71  ? 15  LYS E CG  1 
ATOM   8083  C  CD  . LYS E 1 15  ? 35.146  107.791 83.683  1.00 54.52  ? 15  LYS E CD  1 
ATOM   8084  C  CE  . LYS E 1 15  ? 35.104  108.323 85.111  1.00 60.84  ? 15  LYS E CE  1 
ATOM   8085  N  NZ  . LYS E 1 15  ? 33.935  107.803 85.877  1.00 67.66  ? 15  LYS E NZ  1 
ATOM   8086  N  N   . CYS E 1 16  ? 37.727  103.413 80.884  1.00 41.72  ? 16  CYS E N   1 
ATOM   8087  C  CA  . CYS E 1 16  ? 37.659  102.366 79.871  1.00 49.56  ? 16  CYS E CA  1 
ATOM   8088  C  C   . CYS E 1 16  ? 37.219  101.072 80.546  1.00 48.88  ? 16  CYS E C   1 
ATOM   8089  O  O   . CYS E 1 16  ? 36.716  101.079 81.675  1.00 55.63  ? 16  CYS E O   1 
ATOM   8090  C  CB  . CYS E 1 16  ? 39.009  102.212 79.159  1.00 50.08  ? 16  CYS E CB  1 
ATOM   8091  S  SG  . CYS E 1 16  ? 40.348  101.608 80.236  1.00 48.21  ? 16  CYS E SG  1 
ATOM   8092  N  N   . ARG E 1 17  ? 37.409  99.959  79.849  1.00 48.21  ? 17  ARG E N   1 
ATOM   8093  C  CA  . ARG E 1 17  ? 37.099  98.637  80.372  1.00 52.85  ? 17  ARG E CA  1 
ATOM   8094  C  C   . ARG E 1 17  ? 38.378  97.912  80.780  1.00 52.09  ? 17  ARG E C   1 
ATOM   8095  O  O   . ARG E 1 17  ? 39.483  98.237  80.330  1.00 51.02  ? 17  ARG E O   1 
ATOM   8096  C  CB  . ARG E 1 17  ? 36.333  97.803  79.341  1.00 54.65  ? 17  ARG E CB  1 
ATOM   8097  C  CG  . ARG E 1 17  ? 35.204  98.549  78.680  1.00 54.99  ? 17  ARG E CG  1 
ATOM   8098  C  CD  . ARG E 1 17  ? 34.542  97.702  77.623  1.00 55.00  ? 17  ARG E CD  1 
ATOM   8099  N  NE  . ARG E 1 17  ? 33.094  97.841  77.680  1.00 67.52  ? 17  ARG E NE  1 
ATOM   8100  C  CZ  . ARG E 1 17  ? 32.258  97.373  76.764  1.00 72.08  ? 17  ARG E CZ  1 
ATOM   8101  N  NH1 . ARG E 1 17  ? 32.693  96.697  75.711  1.00 60.43  ? 17  ARG E NH1 1 
ATOM   8102  N  NH2 . ARG E 1 17  ? 30.953  97.599  76.902  1.00 71.54  ? 17  ARG E NH2 1 
ATOM   8103  N  N   . VAL E 1 18  ? 38.210  96.911  81.649  1.00 47.38  ? 18  VAL E N   1 
ATOM   8104  C  CA  . VAL E 1 18  ? 39.361  96.179  82.158  1.00 47.35  ? 18  VAL E CA  1 
ATOM   8105  C  C   . VAL E 1 18  ? 40.080  95.475  81.015  1.00 48.54  ? 18  VAL E C   1 
ATOM   8106  O  O   . VAL E 1 18  ? 41.315  95.480  80.946  1.00 44.83  ? 18  VAL E O   1 
ATOM   8107  C  CB  . VAL E 1 18  ? 38.923  95.198  83.260  1.00 48.94  ? 18  VAL E CB  1 
ATOM   8108  C  CG1 . VAL E 1 18  ? 40.087  94.293  83.674  1.00 50.00  ? 18  VAL E CG1 1 
ATOM   8109  C  CG2 . VAL E 1 18  ? 38.366  95.961  84.463  1.00 53.47  ? 18  VAL E CG2 1 
ATOM   8110  N  N   . CYS E 1 19  ? 39.311  94.893  80.081  1.00 47.60  ? 19  CYS E N   1 
ATOM   8111  C  CA  . CYS E 1 19  ? 39.882  94.226  78.916  1.00 48.63  ? 19  CYS E CA  1 
ATOM   8112  C  C   . CYS E 1 19  ? 40.831  95.131  78.135  1.00 44.83  ? 19  CYS E C   1 
ATOM   8113  O  O   . CYS E 1 19  ? 41.815  94.645  77.570  1.00 48.20  ? 19  CYS E O   1 
ATOM   8114  C  CB  . CYS E 1 19  ? 38.762  93.707  78.001  1.00 51.77  ? 19  CYS E CB  1 
ATOM   8115  S  SG  . CYS E 1 19  ? 37.706  94.984  77.247  1.00 49.59  ? 19  CYS E SG  1 
ATOM   8116  N  N   . ASN E 1 20  ? 40.573  96.445  78.112  1.00 45.83  ? 20  ASN E N   1 
ATOM   8117  C  CA  . ASN E 1 20  ? 41.443  97.356  77.368  1.00 48.47  ? 20  ASN E CA  1 
ATOM   8118  C  C   . ASN E 1 20  ? 42.858  97.369  77.929  1.00 48.49  ? 20  ASN E C   1 
ATOM   8119  O  O   . ASN E 1 20  ? 43.826  97.575  77.183  1.00 43.56  ? 20  ASN E O   1 
ATOM   8120  C  CB  . ASN E 1 20  ? 40.867  98.770  77.386  1.00 46.42  ? 20  ASN E CB  1 
ATOM   8121  C  CG  . ASN E 1 20  ? 39.493  98.841  76.761  1.00 51.25  ? 20  ASN E CG  1 
ATOM   8122  O  OD1 . ASN E 1 20  ? 38.556  99.368  77.357  1.00 52.82  ? 20  ASN E OD1 1 
ATOM   8123  N  ND2 . ASN E 1 20  ? 39.359  98.290  75.560  1.00 45.87  ? 20  ASN E ND2 1 
ATOM   8124  N  N   . ILE E 1 21  ? 42.988  97.157  79.234  1.00 46.23  ? 21  ILE E N   1 
ATOM   8125  C  CA  . ILE E 1 21  ? 44.270  97.150  79.908  1.00 43.73  ? 21  ILE E CA  1 
ATOM   8126  C  C   . ILE E 1 21  ? 44.804  95.733  80.075  1.00 43.27  ? 21  ILE E C   1 
ATOM   8127  O  O   . ILE E 1 21  ? 45.982  95.482  79.830  1.00 42.67  ? 21  ILE E O   1 
ATOM   8128  C  CB  . ILE E 1 21  ? 44.139  97.869  81.267  1.00 44.34  ? 21  ILE E CB  1 
ATOM   8129  C  CG1 . ILE E 1 21  ? 43.791  99.337  81.033  1.00 46.21  ? 21  ILE E CG1 1 
ATOM   8130  C  CG2 . ILE E 1 21  ? 45.419  97.743  82.073  1.00 41.76  ? 21  ILE E CG2 1 
ATOM   8131  C  CD1 . ILE E 1 21  ? 44.885  100.106 80.316  1.00 49.92  ? 21  ILE E CD1 1 
ATOM   8132  N  N   . LYS E 1 22  ? 43.952  94.793  80.472  1.00 47.23  ? 22  LYS E N   1 
ATOM   8133  C  CA  . LYS E 1 22  ? 44.322  93.385  80.592  1.00 47.47  ? 22  LYS E CA  1 
ATOM   8134  C  C   . LYS E 1 22  ? 43.494  92.601  79.579  1.00 51.74  ? 22  LYS E C   1 
ATOM   8135  O  O   . LYS E 1 22  ? 42.270  92.495  79.722  1.00 49.93  ? 22  LYS E O   1 
ATOM   8136  C  CB  . LYS E 1 22  ? 44.108  92.880  82.021  1.00 43.27  ? 22  LYS E CB  1 
ATOM   8137  C  CG  . LYS E 1 22  ? 45.009  93.581  83.034  1.00 46.92  ? 22  LYS E CG  1 
ATOM   8138  C  CD  . LYS E 1 22  ? 44.452  93.539  84.444  1.00 44.44  ? 22  LYS E CD  1 
ATOM   8139  C  CE  . LYS E 1 22  ? 45.367  94.284  85.422  1.00 47.71  ? 22  LYS E CE  1 
ATOM   8140  N  NZ  . LYS E 1 22  ? 45.070  93.989  86.863  1.00 45.78  ? 22  LYS E NZ  1 
ATOM   8141  N  N   . MET E 1 23  ? 44.169  92.055  78.559  1.00 47.72  ? 23  MET E N   1 
ATOM   8142  C  CA  . MET E 1 23  ? 43.491  91.426  77.428  1.00 47.88  ? 23  MET E CA  1 
ATOM   8143  C  C   . MET E 1 23  ? 42.633  90.250  77.886  1.00 45.63  ? 23  MET E C   1 
ATOM   8144  O  O   . MET E 1 23  ? 43.074  89.413  78.679  1.00 45.63  ? 23  MET E O   1 
ATOM   8145  C  CB  . MET E 1 23  ? 44.517  90.952  76.392  1.00 42.67  ? 23  MET E CB  1 
ATOM   8146  C  CG  . MET E 1 23  ? 43.894  90.502  75.078  1.00 42.31  ? 23  MET E CG  1 
ATOM   8147  S  SD  . MET E 1 23  ? 44.927  89.469  74.001  1.00 44.22  ? 23  MET E SD  1 
ATOM   8148  C  CE  . MET E 1 23  ? 45.347  88.105  75.077  1.00 44.33  ? 23  MET E CE  1 
ATOM   8149  N  N   . ASN E 1 24  ? 41.392  90.207  77.391  1.00 47.14  ? 24  ASN E N   1 
ATOM   8150  C  CA  . ASN E 1 24  ? 40.434  89.131  77.654  1.00 47.48  ? 24  ASN E CA  1 
ATOM   8151  C  C   . ASN E 1 24  ? 40.094  88.997  79.142  1.00 48.72  ? 24  ASN E C   1 
ATOM   8152  O  O   . ASN E 1 24  ? 39.632  87.938  79.579  1.00 49.17  ? 24  ASN E O   1 
ATOM   8153  C  CB  . ASN E 1 24  ? 40.944  87.791  77.090  1.00 42.51  ? 24  ASN E CB  1 
ATOM   8154  C  CG  . ASN E 1 24  ? 41.183  87.840  75.571  1.00 47.93  ? 24  ASN E CG  1 
ATOM   8155  O  OD1 . ASN E 1 24  ? 40.553  88.624  74.850  1.00 44.53  ? 24  ASN E OD1 1 
ATOM   8156  N  ND2 . ASN E 1 24  ? 42.113  87.010  75.088  1.00 45.82  ? 24  ASN E ND2 1 
ATOM   8157  N  N   . ALA E 1 25  ? 40.290  90.052  79.940  1.00 50.14  ? 25  ALA E N   1 
ATOM   8158  C  CA  . ALA E 1 25  ? 40.083  89.983  81.386  1.00 53.01  ? 25  ALA E CA  1 
ATOM   8159  C  C   . ALA E 1 25  ? 38.715  90.488  81.844  1.00 56.57  ? 25  ALA E C   1 
ATOM   8160  O  O   . ALA E 1 25  ? 38.474  90.545  83.054  1.00 60.30  ? 25  ALA E O   1 
ATOM   8161  C  CB  . ALA E 1 25  ? 41.178  90.757  82.128  1.00 44.85  ? 25  ALA E CB  1 
ATOM   8162  N  N   . GLY E 1 26  ? 37.821  90.858  80.933  1.00 52.36  ? 26  GLY E N   1 
ATOM   8163  C  CA  . GLY E 1 26  ? 36.459  91.205  81.300  1.00 56.84  ? 26  GLY E CA  1 
ATOM   8164  C  C   . GLY E 1 26  ? 36.076  92.606  80.835  1.00 54.86  ? 26  GLY E C   1 
ATOM   8165  O  O   . GLY E 1 26  ? 36.893  93.399  80.403  1.00 55.97  ? 26  GLY E O   1 
ATOM   8166  N  N   . LEU E 1 27  ? 34.773  92.877  80.963  1.00 58.02  ? 27  LEU E N   1 
ATOM   8167  C  CA  . LEU E 1 27  ? 34.194  94.108  80.434  1.00 56.06  ? 27  LEU E CA  1 
ATOM   8168  C  C   . LEU E 1 27  ? 33.814  95.114  81.519  1.00 56.12  ? 27  LEU E C   1 
ATOM   8169  O  O   . LEU E 1 27  ? 33.228  96.154  81.196  1.00 58.25  ? 27  LEU E O   1 
ATOM   8170  C  CB  . LEU E 1 27  ? 32.975  93.786  79.572  1.00 54.94  ? 27  LEU E CB  1 
ATOM   8171  C  CG  . LEU E 1 27  ? 33.168  92.680  78.534  1.00 59.62  ? 27  LEU E CG  1 
ATOM   8172  C  CD1 . LEU E 1 27  ? 31.832  92.268  77.946  1.00 48.69  ? 27  LEU E CD1 1 
ATOM   8173  C  CD2 . LEU E 1 27  ? 34.134  93.125  77.434  1.00 57.51  ? 27  LEU E CD2 1 
ATOM   8174  N  N   . ASP E 1 28  ? 34.149  94.848  82.785  1.00 59.17  ? 28  ASP E N   1 
ATOM   8175  C  CA  . ASP E 1 28  ? 33.803  95.766  83.868  1.00 57.01  ? 28  ASP E CA  1 
ATOM   8176  C  C   . ASP E 1 28  ? 34.497  97.111  83.689  1.00 59.59  ? 28  ASP E C   1 
ATOM   8177  O  O   . ASP E 1 28  ? 35.559  97.210  83.070  1.00 58.47  ? 28  ASP E O   1 
ATOM   8178  C  CB  . ASP E 1 28  ? 34.191  95.179  85.226  1.00 64.44  ? 28  ASP E CB  1 
ATOM   8179  C  CG  . ASP E 1 28  ? 33.336  93.997  85.622  1.00 68.18  ? 28  ASP E CG  1 
ATOM   8180  O  OD1 . ASP E 1 28  ? 32.166  94.205  86.019  1.00 74.60  ? 28  ASP E OD1 1 
ATOM   8181  O  OD2 . ASP E 1 28  ? 33.839  92.858  85.541  1.00 70.69  ? 28  ASP E OD2 1 
ATOM   8182  N  N   . ASP E 1 29  ? 33.886  98.154  84.254  1.00 61.80  ? 29  ASP E N   1 
ATOM   8183  C  CA  . ASP E 1 29  ? 34.441  99.499  84.160  1.00 57.43  ? 29  ASP E CA  1 
ATOM   8184  C  C   . ASP E 1 29  ? 35.774  99.572  84.893  1.00 54.46  ? 29  ASP E C   1 
ATOM   8185  O  O   . ASP E 1 29  ? 36.026  98.833  85.848  1.00 50.75  ? 29  ASP E O   1 
ATOM   8186  C  CB  . ASP E 1 29  ? 33.473  100.536 84.740  1.00 63.28  ? 29  ASP E CB  1 
ATOM   8187  C  CG  . ASP E 1 29  ? 32.349  100.906 83.778  1.00 67.40  ? 29  ASP E CG  1 
ATOM   8188  O  OD1 . ASP E 1 29  ? 32.629  101.416 82.668  1.00 66.64  ? 29  ASP E OD1 1 
ATOM   8189  O  OD2 . ASP E 1 29  ? 31.174  100.696 84.147  1.00 76.48  ? 29  ASP E OD2 1 
ATOM   8190  N  N   . TYR E 1 30  ? 36.631  100.482 84.433  1.00 54.74  ? 30  TYR E N   1 
ATOM   8191  C  CA  . TYR E 1 30  ? 38.010  100.554 84.890  1.00 51.61  ? 30  TYR E CA  1 
ATOM   8192  C  C   . TYR E 1 30  ? 38.528  101.953 84.594  1.00 50.10  ? 30  TYR E C   1 
ATOM   8193  O  O   . TYR E 1 30  ? 38.141  102.574 83.600  1.00 51.20  ? 30  TYR E O   1 
ATOM   8194  C  CB  . TYR E 1 30  ? 38.858  99.482  84.192  1.00 48.92  ? 30  TYR E CB  1 
ATOM   8195  C  CG  . TYR E 1 30  ? 40.237  99.230  84.759  1.00 47.61  ? 30  TYR E CG  1 
ATOM   8196  C  CD1 . TYR E 1 30  ? 40.409  98.727  86.040  1.00 47.86  ? 30  TYR E CD1 1 
ATOM   8197  C  CD2 . TYR E 1 30  ? 41.370  99.455  83.987  1.00 52.48  ? 30  TYR E CD2 1 
ATOM   8198  C  CE1 . TYR E 1 30  ? 41.674  98.476  86.544  1.00 49.96  ? 30  TYR E CE1 1 
ATOM   8199  C  CE2 . TYR E 1 30  ? 42.637  99.208  84.478  1.00 51.75  ? 30  TYR E CE2 1 
ATOM   8200  C  CZ  . TYR E 1 30  ? 42.789  98.724  85.756  1.00 54.96  ? 30  TYR E CZ  1 
ATOM   8201  O  OH  . TYR E 1 30  ? 44.063  98.483  86.232  1.00 55.70  ? 30  TYR E OH  1 
ATOM   8202  N  N   . GLU E 1 31  ? 39.392  102.450 85.468  1.00 47.88  ? 31  GLU E N   1 
ATOM   8203  C  CA  . GLU E 1 31  ? 39.915  103.799 85.327  1.00 50.15  ? 31  GLU E CA  1 
ATOM   8204  C  C   . GLU E 1 31  ? 41.411  103.790 85.579  1.00 46.31  ? 31  GLU E C   1 
ATOM   8205  O  O   . GLU E 1 31  ? 41.895  103.053 86.442  1.00 45.16  ? 31  GLU E O   1 
ATOM   8206  C  CB  . GLU E 1 31  ? 39.214  104.766 86.287  1.00 50.71  ? 31  GLU E CB  1 
ATOM   8207  C  CG  . GLU E 1 31  ? 39.576  106.228 86.056  1.00 50.03  ? 31  GLU E CG  1 
ATOM   8208  C  CD  . GLU E 1 31  ? 38.571  107.183 86.668  1.00 54.76  ? 31  GLU E CD  1 
ATOM   8209  O  OE1 . GLU E 1 31  ? 37.748  106.728 87.494  1.00 58.00  ? 31  GLU E OE1 1 
ATOM   8210  O  OE2 . GLU E 1 31  ? 38.593  108.384 86.315  1.00 55.24  ? 31  GLU E OE2 1 
ATOM   8211  N  N   . ILE E 1 32  ? 42.145  104.602 84.821  1.00 43.57  ? 32  ILE E N   1 
ATOM   8212  C  CA  . ILE E 1 32  ? 43.607  104.581 84.916  1.00 42.21  ? 32  ILE E CA  1 
ATOM   8213  C  C   . ILE E 1 32  ? 44.139  106.001 84.920  1.00 35.19  ? 32  ILE E C   1 
ATOM   8214  O  O   . ILE E 1 32  ? 43.606  106.896 84.260  1.00 36.57  ? 32  ILE E O   1 
ATOM   8215  C  CB  . ILE E 1 32  ? 44.251  103.790 83.754  1.00 40.75  ? 32  ILE E CB  1 
ATOM   8216  C  CG1 . ILE E 1 32  ? 43.871  104.402 82.398  1.00 43.98  ? 32  ILE E CG1 1 
ATOM   8217  C  CG2 . ILE E 1 32  ? 43.876  102.315 83.824  1.00 45.38  ? 32  ILE E CG2 1 
ATOM   8218  C  CD1 . ILE E 1 32  ? 44.320  103.588 81.202  1.00 38.61  ? 32  ILE E CD1 1 
ATOM   8219  N  N   . PRO E 1 33  ? 45.230  106.218 85.648  1.00 33.82  ? 33  PRO E N   1 
ATOM   8220  C  CA  . PRO E 1 33  ? 45.938  107.498 85.543  1.00 32.68  ? 33  PRO E CA  1 
ATOM   8221  C  C   . PRO E 1 33  ? 46.696  107.607 84.227  1.00 39.59  ? 33  PRO E C   1 
ATOM   8222  O  O   . PRO E 1 33  ? 47.079  106.601 83.624  1.00 38.82  ? 33  PRO E O   1 
ATOM   8223  C  CB  . PRO E 1 33  ? 46.904  107.458 86.724  1.00 37.02  ? 33  PRO E CB  1 
ATOM   8224  C  CG  . PRO E 1 33  ? 47.143  105.995 86.955  1.00 37.62  ? 33  PRO E CG  1 
ATOM   8225  C  CD  . PRO E 1 33  ? 45.874  105.289 86.591  1.00 34.24  ? 33  PRO E CD  1 
ATOM   8226  N  N   . VAL E 1 34  ? 46.914  108.847 83.786  1.00 34.70  ? 34  VAL E N   1 
ATOM   8227  C  CA  . VAL E 1 34  ? 47.710  109.116 82.591  1.00 34.64  ? 34  VAL E CA  1 
ATOM   8228  C  C   . VAL E 1 34  ? 48.975  109.870 82.984  1.00 32.42  ? 34  VAL E C   1 
ATOM   8229  O  O   . VAL E 1 34  ? 49.005  111.106 82.919  1.00 32.32  ? 34  VAL E O   1 
ATOM   8230  C  CB  . VAL E 1 34  ? 46.918  109.908 81.542  1.00 35.30  ? 34  VAL E CB  1 
ATOM   8231  C  CG1 . VAL E 1 34  ? 47.729  110.004 80.242  1.00 31.98  ? 34  VAL E CG1 1 
ATOM   8232  C  CG2 . VAL E 1 34  ? 45.566  109.274 81.299  1.00 34.34  ? 34  VAL E CG2 1 
ATOM   8233  N  N   . PRO E 1 35  ? 50.045  109.179 83.371  1.00 34.95  ? 35  PRO E N   1 
ATOM   8234  C  CA  . PRO E 1 35  ? 51.266  109.881 83.787  1.00 32.56  ? 35  PRO E CA  1 
ATOM   8235  C  C   . PRO E 1 35  ? 51.924  110.648 82.648  1.00 32.60  ? 35  PRO E C   1 
ATOM   8236  O  O   . PRO E 1 35  ? 51.686  110.408 81.460  1.00 29.27  ? 35  PRO E O   1 
ATOM   8237  C  CB  . PRO E 1 35  ? 52.177  108.748 84.284  1.00 33.99  ? 35  PRO E CB  1 
ATOM   8238  C  CG  . PRO E 1 35  ? 51.232  107.584 84.568  1.00 35.23  ? 35  PRO E CG  1 
ATOM   8239  C  CD  . PRO E 1 35  ? 50.168  107.718 83.513  1.00 34.87  ? 35  PRO E CD  1 
ATOM   8240  N  N   . TRP E 1 36  ? 52.739  111.621 83.043  1.00 30.42  ? 36  TRP E N   1 
ATOM   8241  C  CA  . TRP E 1 36  ? 53.762  112.193 82.188  1.00 29.87  ? 36  TRP E CA  1 
ATOM   8242  C  C   . TRP E 1 36  ? 54.847  112.705 83.119  1.00 34.79  ? 36  TRP E C   1 
ATOM   8243  O  O   . TRP E 1 36  ? 54.658  112.767 84.335  1.00 31.67  ? 36  TRP E O   1 
ATOM   8244  C  CB  . TRP E 1 36  ? 53.187  113.263 81.252  1.00 29.39  ? 36  TRP E CB  1 
ATOM   8245  C  CG  . TRP E 1 36  ? 52.694  114.510 81.903  1.00 34.40  ? 36  TRP E CG  1 
ATOM   8246  C  CD1 . TRP E 1 36  ? 51.438  114.739 82.388  1.00 36.70  ? 36  TRP E CD1 1 
ATOM   8247  C  CD2 . TRP E 1 36  ? 53.418  115.730 82.079  1.00 36.23  ? 36  TRP E CD2 1 
ATOM   8248  N  NE1 . TRP E 1 36  ? 51.345  116.014 82.878  1.00 34.16  ? 36  TRP E NE1 1 
ATOM   8249  C  CE2 . TRP E 1 36  ? 52.543  116.649 82.704  1.00 38.29  ? 36  TRP E CE2 1 
ATOM   8250  C  CE3 . TRP E 1 36  ? 54.719  116.136 81.784  1.00 30.57  ? 36  TRP E CE3 1 
ATOM   8251  C  CZ2 . TRP E 1 36  ? 52.933  117.953 83.043  1.00 38.08  ? 36  TRP E CZ2 1 
ATOM   8252  C  CZ3 . TRP E 1 36  ? 55.102  117.433 82.114  1.00 37.05  ? 36  TRP E CZ3 1 
ATOM   8253  C  CH2 . TRP E 1 36  ? 54.208  118.323 82.742  1.00 35.66  ? 36  TRP E CH2 1 
ATOM   8254  N  N   . TYR E 1 37  ? 56.010  113.035 82.565  1.00 29.65  ? 37  TYR E N   1 
ATOM   8255  C  CA  . TYR E 1 37  ? 57.141  113.251 83.452  1.00 28.15  ? 37  TYR E CA  1 
ATOM   8256  C  C   . TYR E 1 37  ? 57.924  114.497 83.073  1.00 30.37  ? 37  TYR E C   1 
ATOM   8257  O  O   . TYR E 1 37  ? 58.067  114.829 81.893  1.00 28.41  ? 37  TYR E O   1 
ATOM   8258  C  CB  . TYR E 1 37  ? 58.057  112.019 83.472  1.00 27.87  ? 37  TYR E CB  1 
ATOM   8259  C  CG  . TYR E 1 37  ? 57.293  110.720 83.599  1.00 30.48  ? 37  TYR E CG  1 
ATOM   8260  C  CD1 . TYR E 1 37  ? 56.916  110.217 84.841  1.00 30.60  ? 37  TYR E CD1 1 
ATOM   8261  C  CD2 . TYR E 1 37  ? 56.932  109.999 82.471  1.00 31.78  ? 37  TYR E CD2 1 
ATOM   8262  C  CE1 . TYR E 1 37  ? 56.207  109.024 84.938  1.00 33.70  ? 37  TYR E CE1 1 
ATOM   8263  C  CE2 . TYR E 1 37  ? 56.230  108.802 82.562  1.00 28.53  ? 37  TYR E CE2 1 
ATOM   8264  C  CZ  . TYR E 1 37  ? 55.868  108.320 83.788  1.00 29.55  ? 37  TYR E CZ  1 
ATOM   8265  O  OH  . TYR E 1 37  ? 55.168  107.127 83.849  1.00 32.01  ? 37  TYR E OH  1 
ATOM   8266  N  N   . LEU E 1 38  ? 58.407  115.189 84.099  1.00 29.47  ? 38  LEU E N   1 
ATOM   8267  C  CA  . LEU E 1 38  ? 59.342  116.290 83.955  1.00 31.65  ? 38  LEU E CA  1 
ATOM   8268  C  C   . LEU E 1 38  ? 60.676  115.888 84.578  1.00 30.24  ? 38  LEU E C   1 
ATOM   8269  O  O   . LEU E 1 38  ? 60.722  115.407 85.716  1.00 28.66  ? 38  LEU E O   1 
ATOM   8270  C  CB  . LEU E 1 38  ? 58.815  117.573 84.622  1.00 31.87  ? 38  LEU E CB  1 
ATOM   8271  C  CG  . LEU E 1 38  ? 59.787  118.775 84.663  1.00 35.68  ? 38  LEU E CG  1 
ATOM   8272  C  CD1 . LEU E 1 38  ? 60.016  119.344 83.266  1.00 32.76  ? 38  LEU E CD1 1 
ATOM   8273  C  CD2 . LEU E 1 38  ? 59.319  119.896 85.612  1.00 35.85  ? 38  LEU E CD2 1 
ATOM   8274  N  N   . ILE E 1 39  ? 61.754  116.079 83.831  1.00 28.23  ? 39  ILE E N   1 
ATOM   8275  C  CA  . ILE E 1 39  ? 63.102  116.023 84.386  1.00 31.14  ? 39  ILE E CA  1 
ATOM   8276  C  C   . ILE E 1 39  ? 63.690  117.412 84.209  1.00 29.77  ? 39  ILE E C   1 
ATOM   8277  O  O   . ILE E 1 39  ? 63.772  117.911 83.079  1.00 30.39  ? 39  ILE E O   1 
ATOM   8278  C  CB  . ILE E 1 39  ? 63.992  114.962 83.711  1.00 28.77  ? 39  ILE E CB  1 
ATOM   8279  C  CG1 . ILE E 1 39  ? 63.364  113.567 83.788  1.00 26.41  ? 39  ILE E CG1 1 
ATOM   8280  C  CG2 . ILE E 1 39  ? 65.397  114.977 84.311  1.00 26.77  ? 39  ILE E CG2 1 
ATOM   8281  C  CD1 . ILE E 1 39  ? 62.484  113.228 82.591  1.00 29.19  ? 39  ILE E CD1 1 
ATOM   8282  N  N   . THR E 1 40  ? 64.033  118.054 85.323  1.00 29.98  ? 40  THR E N   1 
ATOM   8283  C  CA  . THR E 1 40  ? 64.789  119.299 85.318  1.00 27.28  ? 40  THR E CA  1 
ATOM   8284  C  C   . THR E 1 40  ? 66.270  118.959 85.443  1.00 32.50  ? 40  THR E C   1 
ATOM   8285  O  O   . THR E 1 40  ? 66.669  118.194 86.323  1.00 35.81  ? 40  THR E O   1 
ATOM   8286  C  CB  . THR E 1 40  ? 64.343  120.214 86.462  1.00 34.10  ? 40  THR E CB  1 
ATOM   8287  O  OG1 . THR E 1 40  ? 64.621  119.578 87.720  1.00 32.41  ? 40  THR E OG1 1 
ATOM   8288  C  CG2 . THR E 1 40  ? 62.849  120.493 86.364  1.00 33.33  ? 40  THR E CG2 1 
ATOM   8289  N  N   . HIS E 1 41  ? 67.075  119.509 84.544  1.00 33.71  ? 41  HIS E N   1 
ATOM   8290  C  CA  . HIS E 1 41  ? 68.474  119.165 84.410  1.00 36.64  ? 41  HIS E CA  1 
ATOM   8291  C  C   . HIS E 1 41  ? 69.188  120.497 84.261  1.00 33.16  ? 41  HIS E C   1 
ATOM   8292  O  O   . HIS E 1 41  ? 68.637  121.422 83.647  1.00 32.55  ? 41  HIS E O   1 
ATOM   8293  C  CB  . HIS E 1 41  ? 68.701  118.285 83.166  1.00 35.07  ? 41  HIS E CB  1 
ATOM   8294  C  CG  . HIS E 1 41  ? 70.037  117.605 83.098  1.00 35.15  ? 41  HIS E CG  1 
ATOM   8295  N  ND1 . HIS E 1 41  ? 71.174  118.225 82.623  1.00 38.74  ? 41  HIS E ND1 1 
ATOM   8296  C  CD2 . HIS E 1 41  ? 70.396  116.329 83.380  1.00 31.95  ? 41  HIS E CD2 1 
ATOM   8297  C  CE1 . HIS E 1 41  ? 72.183  117.371 82.652  1.00 37.89  ? 41  HIS E CE1 1 
ATOM   8298  N  NE2 . HIS E 1 41  ? 71.736  116.213 83.103  1.00 35.20  ? 41  HIS E NE2 1 
ATOM   8299  N  N   . PRO E 1 42  ? 70.395  120.630 84.799  1.00 36.73  ? 42  PRO E N   1 
ATOM   8300  C  CA  . PRO E 1 42  ? 71.166  121.854 84.542  1.00 35.12  ? 42  PRO E CA  1 
ATOM   8301  C  C   . PRO E 1 42  ? 71.304  122.154 83.065  1.00 37.20  ? 42  PRO E C   1 
ATOM   8302  O  O   . PRO E 1 42  ? 71.301  123.330 82.680  1.00 40.12  ? 42  PRO E O   1 
ATOM   8303  C  CB  . PRO E 1 42  ? 72.529  121.556 85.178  1.00 37.23  ? 42  PRO E CB  1 
ATOM   8304  C  CG  . PRO E 1 42  ? 72.282  120.463 86.145  1.00 41.46  ? 42  PRO E CG  1 
ATOM   8305  C  CD  . PRO E 1 42  ? 71.136  119.658 85.619  1.00 38.40  ? 42  PRO E CD  1 
ATOM   8306  N  N   . LYS E 1 43  ? 71.419  121.129 82.214  1.00 37.68  ? 43  LYS E N   1 
ATOM   8307  C  CA  . LYS E 1 43  ? 71.611  121.384 80.788  1.00 34.45  ? 43  LYS E CA  1 
ATOM   8308  C  C   . LYS E 1 43  ? 70.310  121.676 80.057  1.00 33.33  ? 43  LYS E C   1 
ATOM   8309  O  O   . LYS E 1 43  ? 70.355  121.964 78.858  1.00 33.73  ? 43  LYS E O   1 
ATOM   8310  C  CB  . LYS E 1 43  ? 72.332  120.206 80.119  1.00 35.49  ? 43  LYS E CB  1 
ATOM   8311  C  CG  . LYS E 1 43  ? 73.772  120.005 80.619  1.00 40.79  ? 43  LYS E CG  1 
ATOM   8312  C  CD  . LYS E 1 43  ? 74.291  118.575 80.348  1.00 47.08  ? 43  LYS E CD  1 
ATOM   8313  C  CE  . LYS E 1 43  ? 75.576  118.263 81.135  1.00 52.68  ? 43  LYS E CE  1 
ATOM   8314  N  NZ  . LYS E 1 43  ? 75.514  116.933 81.856  1.00 49.13  ? 43  LYS E NZ  1 
ATOM   8315  N  N   . GLY E 1 44  ? 69.169  121.627 80.738  1.00 29.69  ? 44  GLY E N   1 
ATOM   8316  C  CA  . GLY E 1 44  ? 67.884  121.893 80.112  1.00 31.38  ? 44  GLY E CA  1 
ATOM   8317  C  C   . GLY E 1 44  ? 66.780  120.984 80.615  1.00 31.95  ? 44  GLY E C   1 
ATOM   8318  O  O   . GLY E 1 44  ? 67.014  119.858 81.048  1.00 34.51  ? 44  GLY E O   1 
ATOM   8319  N  N   . ASN E 1 45  ? 65.546  121.477 80.547  1.00 29.50  ? 45  ASN E N   1 
ATOM   8320  C  CA  . ASN E 1 45  ? 64.394  120.711 81.008  1.00 31.41  ? 45  ASN E CA  1 
ATOM   8321  C  C   . ASN E 1 45  ? 63.904  119.728 79.944  1.00 28.02  ? 45  ASN E C   1 
ATOM   8322  O  O   . ASN E 1 45  ? 63.972  119.994 78.744  1.00 30.77  ? 45  ASN E O   1 
ATOM   8323  C  CB  . ASN E 1 45  ? 63.265  121.660 81.408  1.00 32.14  ? 45  ASN E CB  1 
ATOM   8324  C  CG  . ASN E 1 45  ? 63.665  122.536 82.578  1.00 37.32  ? 45  ASN E CG  1 
ATOM   8325  O  OD1 . ASN E 1 45  ? 64.141  122.020 83.586  1.00 35.75  ? 45  ASN E OD1 1 
ATOM   8326  N  ND2 . ASN E 1 45  ? 63.558  123.859 82.422  1.00 29.34  ? 45  ASN E ND2 1 
ATOM   8327  N  N   . VAL E 1 46  ? 63.382  118.596 80.407  1.00 29.12  ? 46  VAL E N   1 
ATOM   8328  C  CA  . VAL E 1 46  ? 62.962  117.493 79.557  1.00 27.03  ? 46  VAL E CA  1 
ATOM   8329  C  C   . VAL E 1 46  ? 61.548  117.102 79.951  1.00 25.56  ? 46  VAL E C   1 
ATOM   8330  O  O   . VAL E 1 46  ? 61.277  116.845 81.131  1.00 30.34  ? 46  VAL E O   1 
ATOM   8331  C  CB  . VAL E 1 46  ? 63.913  116.285 79.688  1.00 30.04  ? 46  VAL E CB  1 
ATOM   8332  C  CG1 . VAL E 1 46  ? 63.442  115.128 78.808  1.00 29.61  ? 46  VAL E CG1 1 
ATOM   8333  C  CG2 . VAL E 1 46  ? 65.324  116.682 79.327  1.00 27.05  ? 46  VAL E CG2 1 
ATOM   8334  N  N   . VAL E 1 47  ? 60.657  117.056 78.966  1.00 25.84  ? 47  VAL E N   1 
ATOM   8335  C  CA  . VAL E 1 47  ? 59.282  116.589 79.119  1.00 25.35  ? 47  VAL E CA  1 
ATOM   8336  C  C   . VAL E 1 47  ? 59.158  115.248 78.408  1.00 24.40  ? 47  VAL E C   1 
ATOM   8337  O  O   . VAL E 1 47  ? 59.574  115.109 77.249  1.00 27.09  ? 47  VAL E O   1 
ATOM   8338  C  CB  . VAL E 1 47  ? 58.287  117.603 78.523  1.00 29.59  ? 47  VAL E CB  1 
ATOM   8339  C  CG1 . VAL E 1 47  ? 56.852  117.069 78.560  1.00 28.00  ? 47  VAL E CG1 1 
ATOM   8340  C  CG2 . VAL E 1 47  ? 58.406  118.963 79.215  1.00 30.16  ? 47  VAL E CG2 1 
ATOM   8341  N  N   . ILE E 1 48  ? 58.571  114.270 79.078  1.00 30.86  ? 48  ILE E N   1 
ATOM   8342  C  CA  . ILE E 1 48  ? 58.344  112.955 78.484  1.00 25.86  ? 48  ILE E CA  1 
ATOM   8343  C  C   . ILE E 1 48  ? 56.852  112.811 78.221  1.00 29.59  ? 48  ILE E C   1 
ATOM   8344  O  O   . ILE E 1 48  ? 56.063  112.734 79.173  1.00 28.58  ? 48  ILE E O   1 
ATOM   8345  C  CB  . ILE E 1 48  ? 58.836  111.821 79.387  1.00 23.29  ? 48  ILE E CB  1 
ATOM   8346  C  CG1 . ILE E 1 48  ? 60.350  111.888 79.586  1.00 23.41  ? 48  ILE E CG1 1 
ATOM   8347  C  CG2 . ILE E 1 48  ? 58.395  110.480 78.802  1.00 25.07  ? 48  ILE E CG2 1 
ATOM   8348  C  CD1 . ILE E 1 48  ? 60.898  110.719 80.408  1.00 19.28  ? 48  ILE E CD1 1 
ATOM   8349  N  N   . ASP E 1 49  ? 56.477  112.750 76.935  1.00 22.20  ? 49  ASP E N   1 
ATOM   8350  C  CA  . ASP E 1 49  ? 55.127  112.476 76.439  1.00 22.60  ? 49  ASP E CA  1 
ATOM   8351  C  C   . ASP E 1 49  ? 54.159  113.643 76.632  1.00 28.17  ? 49  ASP E C   1 
ATOM   8352  O  O   . ASP E 1 49  ? 53.625  114.173 75.647  1.00 25.64  ? 49  ASP E O   1 
ATOM   8353  C  CB  . ASP E 1 49  ? 54.561  111.209 77.077  1.00 24.18  ? 49  ASP E CB  1 
ATOM   8354  C  CG  . ASP E 1 49  ? 55.151  109.949 76.480  1.00 30.09  ? 49  ASP E CG  1 
ATOM   8355  O  OD1 . ASP E 1 49  ? 55.802  110.048 75.401  1.00 29.39  ? 49  ASP E OD1 1 
ATOM   8356  O  OD2 . ASP E 1 49  ? 54.966  108.865 77.087  1.00 26.59  ? 49  ASP E OD2 1 
ATOM   8357  N  N   . GLY E 1 50  ? 53.892  114.036 77.880  1.00 26.78  ? 50  GLY E N   1 
ATOM   8358  C  CA  . GLY E 1 50  ? 53.031  115.188 78.132  1.00 32.41  ? 50  GLY E CA  1 
ATOM   8359  C  C   . GLY E 1 50  ? 51.554  114.894 78.319  1.00 34.44  ? 50  GLY E C   1 
ATOM   8360  O  O   . GLY E 1 50  ? 50.751  115.838 78.385  1.00 32.32  ? 50  GLY E O   1 
ATOM   8361  N  N   . GLY E 1 51  ? 51.169  113.618 78.408  1.00 33.56  ? 51  GLY E N   1 
ATOM   8362  C  CA  . GLY E 1 51  ? 49.796  113.249 78.663  1.00 29.35  ? 51  GLY E CA  1 
ATOM   8363  C  C   . GLY E 1 51  ? 48.908  113.449 77.444  1.00 32.35  ? 51  GLY E C   1 
ATOM   8364  O  O   . GLY E 1 51  ? 49.366  113.630 76.310  1.00 34.15  ? 51  GLY E O   1 
ATOM   8365  N  N   . CYS E 1 52  ? 47.605  113.394 77.705  1.00 26.99  ? 52  CYS E N   1 
ATOM   8366  C  CA  . CYS E 1 52  ? 46.605  113.735 76.706  1.00 29.45  ? 52  CYS E CA  1 
ATOM   8367  C  C   . CYS E 1 52  ? 46.632  115.232 76.442  1.00 37.64  ? 52  CYS E C   1 
ATOM   8368  O  O   . CYS E 1 52  ? 46.879  116.034 77.354  1.00 38.45  ? 52  CYS E O   1 
ATOM   8369  C  CB  . CYS E 1 52  ? 45.205  113.325 77.177  1.00 33.28  ? 52  CYS E CB  1 
ATOM   8370  S  SG  . CYS E 1 52  ? 45.106  111.745 78.081  1.00 36.25  ? 52  CYS E SG  1 
ATOM   8371  N  N   . ALA E 1 53  ? 46.377  115.602 75.185  1.00 31.24  ? 53  ALA E N   1 
ATOM   8372  C  CA  . ALA E 1 53  ? 46.283  117.003 74.803  1.00 36.95  ? 53  ALA E CA  1 
ATOM   8373  C  C   . ALA E 1 53  ? 45.327  117.742 75.723  1.00 40.47  ? 53  ALA E C   1 
ATOM   8374  O  O   . ALA E 1 53  ? 44.333  117.183 76.196  1.00 36.91  ? 53  ALA E O   1 
ATOM   8375  C  CB  . ALA E 1 53  ? 45.799  117.136 73.359  1.00 34.94  ? 53  ALA E CB  1 
ATOM   8376  N  N   . VAL E 1 54  ? 45.636  119.015 75.973  1.00 41.89  ? 54  VAL E N   1 
ATOM   8377  C  CA  . VAL E 1 54  ? 44.785  119.787 76.866  1.00 41.78  ? 54  VAL E CA  1 
ATOM   8378  C  C   . VAL E 1 54  ? 43.395  119.987 76.255  1.00 42.33  ? 54  VAL E C   1 
ATOM   8379  O  O   . VAL E 1 54  ? 42.393  119.985 76.984  1.00 43.68  ? 54  VAL E O   1 
ATOM   8380  C  CB  . VAL E 1 54  ? 45.480  121.110 77.245  1.00 42.26  ? 54  VAL E CB  1 
ATOM   8381  C  CG1 . VAL E 1 54  ? 45.778  121.962 76.018  1.00 36.52  ? 54  VAL E CG1 1 
ATOM   8382  C  CG2 . VAL E 1 54  ? 44.669  121.855 78.300  1.00 42.59  ? 54  VAL E CG2 1 
ATOM   8383  N  N   . GLU E 1 55  ? 43.293  120.076 74.917  1.00 40.61  ? 55  GLU E N   1 
ATOM   8384  C  CA  . GLU E 1 55  ? 41.984  120.125 74.256  1.00 42.58  ? 55  GLU E CA  1 
ATOM   8385  C  C   . GLU E 1 55  ? 41.032  119.042 74.752  1.00 46.48  ? 55  GLU E C   1 
ATOM   8386  O  O   . GLU E 1 55  ? 39.812  119.205 74.643  1.00 50.64  ? 55  GLU E O   1 
ATOM   8387  C  CB  . GLU E 1 55  ? 42.122  119.974 72.733  1.00 41.55  ? 55  GLU E CB  1 
ATOM   8388  C  CG  . GLU E 1 55  ? 42.768  121.128 72.008  1.00 36.49  ? 55  GLU E CG  1 
ATOM   8389  C  CD  . GLU E 1 55  ? 44.281  121.113 72.128  1.00 44.23  ? 55  GLU E CD  1 
ATOM   8390  O  OE1 . GLU E 1 55  ? 44.811  120.373 72.991  1.00 43.84  ? 55  GLU E OE1 1 
ATOM   8391  O  OE2 . GLU E 1 55  ? 44.944  121.833 71.351  1.00 42.70  ? 55  GLU E OE2 1 
ATOM   8392  N  N   . CYS E 1 56  ? 41.557  117.937 75.288  1.00 43.28  ? 56  CYS E N   1 
ATOM   8393  C  CA  . CYS E 1 56  ? 40.697  116.860 75.761  1.00 45.68  ? 56  CYS E CA  1 
ATOM   8394  C  C   . CYS E 1 56  ? 39.922  117.250 77.004  1.00 47.28  ? 56  CYS E C   1 
ATOM   8395  O  O   . CYS E 1 56  ? 38.881  116.645 77.280  1.00 41.40  ? 56  CYS E O   1 
ATOM   8396  C  CB  . CYS E 1 56  ? 41.521  115.597 76.043  1.00 45.13  ? 56  CYS E CB  1 
ATOM   8397  S  SG  . CYS E 1 56  ? 42.230  114.878 74.550  1.00 42.72  ? 56  CYS E SG  1 
ATOM   8398  N  N   . ALA E 1 57  ? 40.415  118.233 77.762  1.00 48.47  ? 57  ALA E N   1 
ATOM   8399  C  CA  . ALA E 1 57  ? 39.685  118.705 78.930  1.00 50.18  ? 57  ALA E CA  1 
ATOM   8400  C  C   . ALA E 1 57  ? 38.370  119.371 78.538  1.00 52.10  ? 57  ALA E C   1 
ATOM   8401  O  O   . ALA E 1 57  ? 37.381  119.264 79.269  1.00 51.03  ? 57  ALA E O   1 
ATOM   8402  C  CB  . ALA E 1 57  ? 40.556  119.677 79.728  1.00 53.17  ? 57  ALA E CB  1 
ATOM   8403  N  N   . SER E 1 58  ? 38.338  120.052 77.395  1.00 52.89  ? 58  SER E N   1 
ATOM   8404  C  CA  . SER E 1 58  ? 37.153  120.794 76.983  1.00 54.65  ? 58  SER E CA  1 
ATOM   8405  C  C   . SER E 1 58  ? 36.252  119.960 76.082  1.00 56.18  ? 58  SER E C   1 
ATOM   8406  O  O   . SER E 1 58  ? 35.063  119.787 76.370  1.00 58.97  ? 58  SER E O   1 
ATOM   8407  C  CB  . SER E 1 58  ? 37.570  122.083 76.269  1.00 54.63  ? 58  SER E CB  1 
ATOM   8408  O  OG  . SER E 1 58  ? 38.224  122.959 77.164  1.00 57.19  ? 58  SER E OG  1 
ATOM   8409  N  N   . ASP E 1 59  ? 36.812  119.433 74.993  1.00 55.02  ? 59  ASP E N   1 
ATOM   8410  C  CA  . ASP E 1 59  ? 36.037  118.801 73.923  1.00 54.25  ? 59  ASP E CA  1 
ATOM   8411  C  C   . ASP E 1 59  ? 36.701  117.497 73.489  1.00 50.86  ? 59  ASP E C   1 
ATOM   8412  O  O   . ASP E 1 59  ? 37.276  117.405 72.396  1.00 52.02  ? 59  ASP E O   1 
ATOM   8413  C  CB  . ASP E 1 59  ? 35.892  119.758 72.739  1.00 50.93  ? 59  ASP E CB  1 
ATOM   8414  C  CG  . ASP E 1 59  ? 34.897  119.265 71.707  1.00 50.03  ? 59  ASP E CG  1 
ATOM   8415  O  OD1 . ASP E 1 59  ? 34.148  118.298 71.992  1.00 44.72  ? 59  ASP E OD1 1 
ATOM   8416  O  OD2 . ASP E 1 59  ? 34.875  119.847 70.601  1.00 52.14  ? 59  ASP E OD2 1 
ATOM   8417  N  N   . PRO E 1 60  ? 36.608  116.450 74.315  1.00 45.79  ? 60  PRO E N   1 
ATOM   8418  C  CA  . PRO E 1 60  ? 37.238  115.171 73.937  1.00 49.33  ? 60  PRO E CA  1 
ATOM   8419  C  C   . PRO E 1 60  ? 36.699  114.597 72.639  1.00 51.05  ? 60  PRO E C   1 
ATOM   8420  O  O   . PRO E 1 60  ? 37.484  114.106 71.814  1.00 47.11  ? 60  PRO E O   1 
ATOM   8421  C  CB  . PRO E 1 60  ? 36.931  114.241 75.120  1.00 51.14  ? 60  PRO E CB  1 
ATOM   8422  C  CG  . PRO E 1 60  ? 36.223  115.054 76.152  1.00 50.25  ? 60  PRO E CG  1 
ATOM   8423  C  CD  . PRO E 1 60  ? 35.913  116.406 75.612  1.00 50.76  ? 60  PRO E CD  1 
ATOM   8424  N  N   . LYS E 1 61  ? 35.378  114.627 72.435  1.00 48.59  ? 61  LYS E N   1 
ATOM   8425  C  CA  . LYS E 1 61  ? 34.828  114.085 71.195  1.00 49.04  ? 61  LYS E CA  1 
ATOM   8426  C  C   . LYS E 1 61  ? 35.343  114.861 69.993  1.00 49.03  ? 61  LYS E C   1 
ATOM   8427  O  O   . LYS E 1 61  ? 35.706  114.267 68.973  1.00 48.55  ? 61  LYS E O   1 
ATOM   8428  C  CB  . LYS E 1 61  ? 33.293  114.096 71.222  1.00 51.28  ? 61  LYS E CB  1 
ATOM   8429  C  CG  . LYS E 1 61  ? 32.658  113.306 72.368  1.00 56.73  ? 61  LYS E CG  1 
ATOM   8430  C  CD  . LYS E 1 61  ? 31.234  112.843 72.016  1.00 60.55  ? 61  LYS E CD  1 
ATOM   8431  C  CE  . LYS E 1 61  ? 30.494  112.277 73.237  1.00 60.48  ? 61  LYS E CE  1 
ATOM   8432  N  NZ  . LYS E 1 61  ? 29.204  111.590 72.890  1.00 59.78  ? 61  LYS E NZ  1 
ATOM   8433  N  N   . GLY E 1 62  ? 35.404  116.189 70.103  1.00 47.06  ? 62  GLY E N   1 
ATOM   8434  C  CA  . GLY E 1 62  ? 35.890  116.984 68.990  1.00 46.44  ? 62  GLY E CA  1 
ATOM   8435  C  C   . GLY E 1 62  ? 37.354  116.733 68.676  1.00 46.79  ? 62  GLY E C   1 
ATOM   8436  O  O   . GLY E 1 62  ? 37.739  116.643 67.508  1.00 47.93  ? 62  GLY E O   1 
ATOM   8437  N  N   . TYR E 1 63  ? 38.190  116.599 69.706  1.00 44.76  ? 63  TYR E N   1 
ATOM   8438  C  CA  . TYR E 1 63  ? 39.620  116.492 69.433  1.00 44.26  ? 63  TYR E CA  1 
ATOM   8439  C  C   . TYR E 1 63  ? 40.052  115.054 69.147  1.00 39.59  ? 63  TYR E C   1 
ATOM   8440  O  O   . TYR E 1 63  ? 40.792  114.814 68.197  1.00 37.89  ? 63  TYR E O   1 
ATOM   8441  C  CB  . TYR E 1 63  ? 40.437  117.078 70.590  1.00 40.87  ? 63  TYR E CB  1 
ATOM   8442  C  CG  . TYR E 1 63  ? 41.862  117.403 70.187  1.00 39.37  ? 63  TYR E CG  1 
ATOM   8443  C  CD1 . TYR E 1 63  ? 42.131  118.395 69.249  1.00 37.16  ? 63  TYR E CD1 1 
ATOM   8444  C  CD2 . TYR E 1 63  ? 42.937  116.703 70.727  1.00 35.84  ? 63  TYR E CD2 1 
ATOM   8445  C  CE1 . TYR E 1 63  ? 43.431  118.693 68.871  1.00 37.81  ? 63  TYR E CE1 1 
ATOM   8446  C  CE2 . TYR E 1 63  ? 44.243  116.991 70.350  1.00 37.12  ? 63  TYR E CE2 1 
ATOM   8447  C  CZ  . TYR E 1 63  ? 44.483  117.979 69.426  1.00 38.65  ? 63  TYR E CZ  1 
ATOM   8448  O  OH  . TYR E 1 63  ? 45.779  118.261 69.067  1.00 39.42  ? 63  TYR E OH  1 
ATOM   8449  N  N   . TRP E 1 64  ? 39.589  114.094 69.937  1.00 39.87  ? 64  TRP E N   1 
ATOM   8450  C  CA  . TRP E 1 64  ? 39.957  112.698 69.733  1.00 41.15  ? 64  TRP E CA  1 
ATOM   8451  C  C   . TRP E 1 64  ? 39.052  111.949 68.758  1.00 43.95  ? 64  TRP E C   1 
ATOM   8452  O  O   . TRP E 1 64  ? 39.530  111.046 68.058  1.00 46.26  ? 64  TRP E O   1 
ATOM   8453  C  CB  . TRP E 1 64  ? 39.953  111.945 71.060  1.00 35.90  ? 64  TRP E CB  1 
ATOM   8454  C  CG  . TRP E 1 64  ? 41.183  112.112 71.864  1.00 33.04  ? 64  TRP E CG  1 
ATOM   8455  C  CD1 . TRP E 1 64  ? 42.257  112.911 71.582  1.00 32.38  ? 64  TRP E CD1 1 
ATOM   8456  C  CD2 . TRP E 1 64  ? 41.481  111.452 73.100  1.00 27.12  ? 64  TRP E CD2 1 
ATOM   8457  N  NE1 . TRP E 1 64  ? 43.208  112.784 72.577  1.00 29.55  ? 64  TRP E NE1 1 
ATOM   8458  C  CE2 . TRP E 1 64  ? 42.755  111.888 73.512  1.00 30.22  ? 64  TRP E CE2 1 
ATOM   8459  C  CE3 . TRP E 1 64  ? 40.796  110.521 73.892  1.00 35.91  ? 64  TRP E CE3 1 
ATOM   8460  C  CZ2 . TRP E 1 64  ? 43.352  111.440 74.699  1.00 34.12  ? 64  TRP E CZ2 1 
ATOM   8461  C  CZ3 . TRP E 1 64  ? 41.393  110.073 75.073  1.00 34.63  ? 64  TRP E CZ3 1 
ATOM   8462  C  CH2 . TRP E 1 64  ? 42.658  110.530 75.458  1.00 33.86  ? 64  TRP E CH2 1 
ATOM   8463  N  N   . GLY E 1 65  ? 37.759  112.259 68.708  1.00 41.79  ? 65  GLY E N   1 
ATOM   8464  C  CA  . GLY E 1 65  ? 36.891  111.563 67.772  1.00 38.68  ? 65  GLY E CA  1 
ATOM   8465  C  C   . GLY E 1 65  ? 36.310  110.271 68.314  1.00 39.71  ? 65  GLY E C   1 
ATOM   8466  O  O   . GLY E 1 65  ? 36.083  110.140 69.519  1.00 40.83  ? 65  GLY E O   1 
ATOM   8467  N  N   . ASP E 1 66  ? 36.090  109.297 67.428  1.00 38.54  ? 66  ASP E N   1 
ATOM   8468  C  CA  . ASP E 1 66  ? 35.358  108.084 67.797  1.00 43.34  ? 66  ASP E CA  1 
ATOM   8469  C  C   . ASP E 1 66  ? 36.030  107.299 68.918  1.00 44.40  ? 66  ASP E C   1 
ATOM   8470  O  O   . ASP E 1 66  ? 35.349  106.570 69.649  1.00 45.95  ? 66  ASP E O   1 
ATOM   8471  C  CB  . ASP E 1 66  ? 35.194  107.179 66.575  1.00 51.78  ? 66  ASP E CB  1 
ATOM   8472  C  CG  . ASP E 1 66  ? 34.135  107.673 65.613  1.00 51.60  ? 66  ASP E CG  1 
ATOM   8473  O  OD1 . ASP E 1 66  ? 33.517  108.731 65.877  1.00 50.92  ? 66  ASP E OD1 1 
ATOM   8474  O  OD2 . ASP E 1 66  ? 33.917  106.991 64.588  1.00 58.57  ? 66  ASP E OD2 1 
ATOM   8475  N  N   . ILE E 1 67  ? 37.352  107.420 69.069  1.00 36.90  ? 67  ILE E N   1 
ATOM   8476  C  CA  . ILE E 1 67  ? 38.079  106.596 70.029  1.00 41.78  ? 67  ILE E CA  1 
ATOM   8477  C  C   . ILE E 1 67  ? 37.622  106.883 71.449  1.00 42.13  ? 67  ILE E C   1 
ATOM   8478  O  O   . ILE E 1 67  ? 37.778  106.033 72.333  1.00 40.99  ? 67  ILE E O   1 
ATOM   8479  C  CB  . ILE E 1 67  ? 39.611  106.806 69.857  1.00 41.99  ? 67  ILE E CB  1 
ATOM   8480  C  CG1 . ILE E 1 67  ? 40.425  105.878 70.764  1.00 36.66  ? 67  ILE E CG1 1 
ATOM   8481  C  CG2 . ILE E 1 67  ? 39.997  108.258 70.102  1.00 38.34  ? 67  ILE E CG2 1 
ATOM   8482  C  CD1 . ILE E 1 67  ? 40.330  104.426 70.416  1.00 36.84  ? 67  ILE E CD1 1 
ATOM   8483  N  N   . THR E 1 68  ? 37.025  108.058 71.683  1.00 43.30  ? 68  THR E N   1 
ATOM   8484  C  CA  . THR E 1 68  ? 36.514  108.398 73.005  1.00 45.17  ? 68  THR E CA  1 
ATOM   8485  C  C   . THR E 1 68  ? 35.481  107.387 73.500  1.00 45.78  ? 68  THR E C   1 
ATOM   8486  O  O   . THR E 1 68  ? 35.254  107.296 74.708  1.00 49.04  ? 68  THR E O   1 
ATOM   8487  C  CB  . THR E 1 68  ? 35.910  109.811 72.992  1.00 47.91  ? 68  THR E CB  1 
ATOM   8488  O  OG1 . THR E 1 68  ? 35.000  109.934 71.895  1.00 51.46  ? 68  THR E OG1 1 
ATOM   8489  C  CG2 . THR E 1 68  ? 36.994  110.860 72.809  1.00 44.02  ? 68  THR E CG2 1 
ATOM   8490  N  N   . SER E 1 69  ? 34.863  106.613 72.602  1.00 46.29  ? 69  SER E N   1 
ATOM   8491  C  CA  . SER E 1 69  ? 33.942  105.570 73.039  1.00 45.28  ? 69  SER E CA  1 
ATOM   8492  C  C   . SER E 1 69  ? 34.656  104.407 73.720  1.00 48.63  ? 69  SER E C   1 
ATOM   8493  O  O   . SER E 1 69  ? 34.006  103.613 74.407  1.00 51.91  ? 69  SER E O   1 
ATOM   8494  C  CB  . SER E 1 69  ? 33.136  105.055 71.848  1.00 45.19  ? 69  SER E CB  1 
ATOM   8495  O  OG  . SER E 1 69  ? 33.984  104.420 70.912  1.00 47.21  ? 69  SER E OG  1 
ATOM   8496  N  N   . VAL E 1 70  ? 35.968  104.285 73.543  1.00 44.06  ? 70  VAL E N   1 
ATOM   8497  C  CA  . VAL E 1 70  ? 36.778  103.301 74.259  1.00 43.54  ? 70  VAL E CA  1 
ATOM   8498  C  C   . VAL E 1 70  ? 37.493  103.931 75.453  1.00 47.27  ? 70  VAL E C   1 
ATOM   8499  O  O   . VAL E 1 70  ? 37.417  103.424 76.574  1.00 48.38  ? 70  VAL E O   1 
ATOM   8500  C  CB  . VAL E 1 70  ? 37.788  102.637 73.293  1.00 47.11  ? 70  VAL E CB  1 
ATOM   8501  C  CG1 . VAL E 1 70  ? 38.544  101.501 74.000  1.00 44.19  ? 70  VAL E CG1 1 
ATOM   8502  C  CG2 . VAL E 1 70  ? 37.093  102.135 72.033  1.00 43.97  ? 70  VAL E CG2 1 
ATOM   8503  N  N   . TYR E 1 71  ? 38.204  105.035 75.220  1.00 44.24  ? 71  TYR E N   1 
ATOM   8504  C  CA  . TYR E 1 71  ? 38.967  105.741 76.246  1.00 46.04  ? 71  TYR E CA  1 
ATOM   8505  C  C   . TYR E 1 71  ? 38.346  107.120 76.426  1.00 44.89  ? 71  TYR E C   1 
ATOM   8506  O  O   . TYR E 1 71  ? 38.500  107.989 75.560  1.00 41.53  ? 71  TYR E O   1 
ATOM   8507  C  CB  . TYR E 1 71  ? 40.437  105.862 75.847  1.00 43.35  ? 71  TYR E CB  1 
ATOM   8508  C  CG  . TYR E 1 71  ? 41.104  104.542 75.553  1.00 45.50  ? 71  TYR E CG  1 
ATOM   8509  C  CD1 . TYR E 1 71  ? 41.487  103.698 76.584  1.00 44.52  ? 71  TYR E CD1 1 
ATOM   8510  C  CD2 . TYR E 1 71  ? 41.363  104.144 74.245  1.00 41.54  ? 71  TYR E CD2 1 
ATOM   8511  C  CE1 . TYR E 1 71  ? 42.101  102.485 76.331  1.00 46.53  ? 71  TYR E CE1 1 
ATOM   8512  C  CE2 . TYR E 1 71  ? 41.980  102.936 73.978  1.00 45.47  ? 71  TYR E CE2 1 
ATOM   8513  C  CZ  . TYR E 1 71  ? 42.345  102.105 75.025  1.00 47.06  ? 71  TYR E CZ  1 
ATOM   8514  O  OH  . TYR E 1 71  ? 42.967  100.897 74.777  1.00 47.23  ? 71  TYR E OH  1 
ATOM   8515  N  N   . TRP E 1 72  ? 37.626  107.324 77.532  1.00 45.47  ? 72  TRP E N   1 
ATOM   8516  C  CA  . TRP E 1 72  ? 37.061  108.637 77.810  1.00 44.40  ? 72  TRP E CA  1 
ATOM   8517  C  C   . TRP E 1 72  ? 38.006  109.417 78.719  1.00 40.25  ? 72  TRP E C   1 
ATOM   8518  O  O   . TRP E 1 72  ? 38.291  108.961 79.834  1.00 38.69  ? 72  TRP E O   1 
ATOM   8519  C  CB  . TRP E 1 72  ? 35.688  108.522 78.451  1.00 49.43  ? 72  TRP E CB  1 
ATOM   8520  C  CG  . TRP E 1 72  ? 35.128  109.870 78.774  1.00 50.47  ? 72  TRP E CG  1 
ATOM   8521  C  CD1 . TRP E 1 72  ? 35.146  110.486 79.989  1.00 49.86  ? 72  TRP E CD1 1 
ATOM   8522  C  CD2 . TRP E 1 72  ? 34.508  110.791 77.863  1.00 46.38  ? 72  TRP E CD2 1 
ATOM   8523  N  NE1 . TRP E 1 72  ? 34.570  111.726 79.895  1.00 52.30  ? 72  TRP E NE1 1 
ATOM   8524  C  CE2 . TRP E 1 72  ? 34.172  111.940 78.601  1.00 52.23  ? 72  TRP E CE2 1 
ATOM   8525  C  CE3 . TRP E 1 72  ? 34.207  110.755 76.499  1.00 47.65  ? 72  TRP E CE3 1 
ATOM   8526  C  CZ2 . TRP E 1 72  ? 33.544  113.047 78.022  1.00 52.80  ? 72  TRP E CZ2 1 
ATOM   8527  C  CZ3 . TRP E 1 72  ? 33.583  111.854 75.924  1.00 52.38  ? 72  TRP E CZ3 1 
ATOM   8528  C  CH2 . TRP E 1 72  ? 33.257  112.983 76.687  1.00 54.48  ? 72  TRP E CH2 1 
ATOM   8529  N  N   . PRO E 1 73  ? 38.523  110.574 78.286  1.00 34.17  ? 73  PRO E N   1 
ATOM   8530  C  CA  . PRO E 1 73  ? 39.498  111.306 79.105  1.00 43.82  ? 73  PRO E CA  1 
ATOM   8531  C  C   . PRO E 1 73  ? 38.856  112.249 80.120  1.00 44.13  ? 73  PRO E C   1 
ATOM   8532  O  O   . PRO E 1 73  ? 38.003  113.068 79.767  1.00 41.56  ? 73  PRO E O   1 
ATOM   8533  C  CB  . PRO E 1 73  ? 40.303  112.083 78.057  1.00 39.05  ? 73  PRO E CB  1 
ATOM   8534  C  CG  . PRO E 1 73  ? 39.303  112.353 76.970  1.00 37.84  ? 73  PRO E CG  1 
ATOM   8535  C  CD  . PRO E 1 73  ? 38.291  111.228 76.989  1.00 38.35  ? 73  PRO E CD  1 
ATOM   8536  N  N   . VAL E 1 74  ? 39.274  112.148 81.378  1.00 45.21  ? 74  VAL E N   1 
ATOM   8537  C  CA  . VAL E 1 74  ? 38.784  113.000 82.456  1.00 44.13  ? 74  VAL E CA  1 
ATOM   8538  C  C   . VAL E 1 74  ? 39.964  113.836 82.935  1.00 41.79  ? 74  VAL E C   1 
ATOM   8539  O  O   . VAL E 1 74  ? 40.790  113.357 83.722  1.00 43.58  ? 74  VAL E O   1 
ATOM   8540  C  CB  . VAL E 1 74  ? 38.179  112.185 83.606  1.00 45.35  ? 74  VAL E CB  1 
ATOM   8541  C  CG1 . VAL E 1 74  ? 37.737  113.105 84.737  1.00 41.37  ? 74  VAL E CG1 1 
ATOM   8542  C  CG2 . VAL E 1 74  ? 37.022  111.347 83.113  1.00 42.92  ? 74  VAL E CG2 1 
ATOM   8543  N  N   . MET E 1 75  ? 40.059  115.080 82.463  1.00 41.42  ? 75  MET E N   1 
ATOM   8544  C  CA  . MET E 1 75  ? 41.088  115.977 82.973  1.00 44.62  ? 75  MET E CA  1 
ATOM   8545  C  C   . MET E 1 75  ? 40.541  117.398 83.007  1.00 47.40  ? 75  MET E C   1 
ATOM   8546  O  O   . MET E 1 75  ? 39.592  117.738 82.295  1.00 41.37  ? 75  MET E O   1 
ATOM   8547  C  CB  . MET E 1 75  ? 42.373  115.948 82.120  1.00 41.70  ? 75  MET E CB  1 
ATOM   8548  C  CG  . MET E 1 75  ? 42.137  116.185 80.634  1.00 43.29  ? 75  MET E CG  1 
ATOM   8549  S  SD  . MET E 1 75  ? 43.629  116.156 79.593  1.00 45.71  ? 75  MET E SD  1 
ATOM   8550  C  CE  . MET E 1 75  ? 44.409  117.749 79.878  1.00 40.21  ? 75  MET E CE  1 
ATOM   8551  N  N   . ARG E 1 76  ? 41.181  118.237 83.817  1.00 43.54  ? 76  ARG E N   1 
ATOM   8552  C  CA  . ARG E 1 76  ? 40.906  119.665 83.827  1.00 49.15  ? 76  ARG E CA  1 
ATOM   8553  C  C   . ARG E 1 76  ? 41.953  120.418 83.011  1.00 48.29  ? 76  ARG E C   1 
ATOM   8554  O  O   . ARG E 1 76  ? 43.083  119.954 82.828  1.00 47.44  ? 76  ARG E O   1 
ATOM   8555  C  CB  . ARG E 1 76  ? 40.883  120.195 85.260  1.00 53.53  ? 76  ARG E CB  1 
ATOM   8556  C  CG  . ARG E 1 76  ? 40.220  119.255 86.254  1.00 56.09  ? 76  ARG E CG  1 
ATOM   8557  C  CD  . ARG E 1 76  ? 40.363  119.799 87.663  1.00 58.33  ? 76  ARG E CD  1 
ATOM   8558  N  NE  . ARG E 1 76  ? 41.732  119.671 88.150  1.00 58.52  ? 76  ARG E NE  1 
ATOM   8559  C  CZ  . ARG E 1 76  ? 42.237  118.562 88.678  1.00 57.60  ? 76  ARG E CZ  1 
ATOM   8560  N  NH1 . ARG E 1 76  ? 41.507  117.464 88.815  1.00 58.35  ? 76  ARG E NH1 1 
ATOM   8561  N  NH2 . ARG E 1 76  ? 43.504  118.557 89.087  1.00 52.80  ? 76  ARG E NH2 1 
ATOM   8562  N  N   . ILE E 1 77  ? 41.567  121.607 82.534  1.00 45.03  ? 77  ILE E N   1 
ATOM   8563  C  CA  . ILE E 1 77  ? 42.493  122.430 81.755  1.00 49.92  ? 77  ILE E CA  1 
ATOM   8564  C  C   . ILE E 1 77  ? 43.806  122.644 82.508  1.00 50.36  ? 77  ILE E C   1 
ATOM   8565  O  O   . ILE E 1 77  ? 44.886  122.676 81.900  1.00 49.12  ? 77  ILE E O   1 
ATOM   8566  C  CB  . ILE E 1 77  ? 41.840  123.774 81.378  1.00 50.83  ? 77  ILE E CB  1 
ATOM   8567  C  CG1 . ILE E 1 77  ? 40.600  123.561 80.521  1.00 50.89  ? 77  ILE E CG1 1 
ATOM   8568  C  CG2 . ILE E 1 77  ? 42.833  124.668 80.641  1.00 47.36  ? 77  ILE E CG2 1 
ATOM   8569  C  CD1 . ILE E 1 77  ? 40.009  124.862 79.995  1.00 44.33  ? 77  ILE E CD1 1 
ATOM   8570  N  N   . GLU E 1 78  ? 43.736  122.788 83.842  1.00 49.12  ? 78  GLU E N   1 
ATOM   8571  C  CA  . GLU E 1 78  ? 44.942  122.994 84.655  1.00 51.73  ? 78  GLU E CA  1 
ATOM   8572  C  C   . GLU E 1 78  ? 45.973  121.904 84.422  1.00 48.49  ? 78  GLU E C   1 
ATOM   8573  O  O   . GLU E 1 78  ? 47.167  122.105 84.677  1.00 45.30  ? 78  GLU E O   1 
ATOM   8574  C  CB  . GLU E 1 78  ? 44.623  123.004 86.158  1.00 53.74  ? 78  GLU E CB  1 
ATOM   8575  C  CG  . GLU E 1 78  ? 43.681  124.068 86.628  1.00 60.60  ? 78  GLU E CG  1 
ATOM   8576  C  CD  . GLU E 1 78  ? 42.241  123.690 86.373  1.00 63.00  ? 78  GLU E CD  1 
ATOM   8577  O  OE1 . GLU E 1 78  ? 41.745  122.770 87.066  1.00 62.89  ? 78  GLU E OE1 1 
ATOM   8578  O  OE2 . GLU E 1 78  ? 41.627  124.299 85.465  1.00 58.63  ? 78  GLU E OE2 1 
ATOM   8579  N  N   . GLU E 1 79  ? 45.527  120.736 83.971  1.00 48.13  ? 79  GLU E N   1 
ATOM   8580  C  CA  . GLU E 1 79  ? 46.384  119.572 83.881  1.00 45.65  ? 79  GLU E CA  1 
ATOM   8581  C  C   . GLU E 1 79  ? 47.161  119.502 82.574  1.00 45.41  ? 79  GLU E C   1 
ATOM   8582  O  O   . GLU E 1 79  ? 48.117  118.726 82.489  1.00 42.94  ? 79  GLU E O   1 
ATOM   8583  C  CB  . GLU E 1 79  ? 45.543  118.314 84.086  1.00 42.64  ? 79  GLU E CB  1 
ATOM   8584  C  CG  . GLU E 1 79  ? 44.974  118.218 85.494  1.00 44.03  ? 79  GLU E CG  1 
ATOM   8585  C  CD  . GLU E 1 79  ? 44.191  116.942 85.726  1.00 44.34  ? 79  GLU E CD  1 
ATOM   8586  O  OE1 . GLU E 1 79  ? 43.026  116.865 85.276  1.00 47.20  ? 79  GLU E OE1 1 
ATOM   8587  O  OE2 . GLU E 1 79  ? 44.729  116.019 86.369  1.00 44.76  ? 79  GLU E OE2 1 
ATOM   8588  N  N   . GLY E 1 80  ? 46.784  120.293 81.571  1.00 45.09  ? 80  GLY E N   1 
ATOM   8589  C  CA  . GLY E 1 80  ? 47.524  120.365 80.325  1.00 45.16  ? 80  GLY E CA  1 
ATOM   8590  C  C   . GLY E 1 80  ? 48.990  120.604 80.603  1.00 42.68  ? 80  GLY E C   1 
ATOM   8591  O  O   . GLY E 1 80  ? 49.325  121.310 81.553  1.00 43.94  ? 80  GLY E O   1 
ATOM   8592  N  N   . CYS E 1 81  ? 49.880  120.010 79.809  1.00 42.76  ? 81  CYS E N   1 
ATOM   8593  C  CA  . CYS E 1 81  ? 51.282  120.014 80.210  1.00 44.83  ? 81  CYS E CA  1 
ATOM   8594  C  C   . CYS E 1 81  ? 51.892  121.402 80.088  1.00 39.05  ? 81  CYS E C   1 
ATOM   8595  O  O   . CYS E 1 81  ? 52.752  121.760 80.903  1.00 38.94  ? 81  CYS E O   1 
ATOM   8596  C  CB  . CYS E 1 81  ? 52.088  118.968 79.413  1.00 37.21  ? 81  CYS E CB  1 
ATOM   8597  S  SG  . CYS E 1 81  ? 52.127  119.159 77.619  1.00 37.60  ? 81  CYS E SG  1 
ATOM   8598  N  N   . VAL E 1 82  ? 51.460  122.201 79.109  1.00 36.05  ? 82  VAL E N   1 
ATOM   8599  C  CA  . VAL E 1 82  ? 51.926  123.587 79.051  1.00 40.48  ? 82  VAL E CA  1 
ATOM   8600  C  C   . VAL E 1 82  ? 51.498  124.329 80.307  1.00 42.82  ? 82  VAL E C   1 
ATOM   8601  O  O   . VAL E 1 82  ? 52.305  125.004 80.960  1.00 40.18  ? 82  VAL E O   1 
ATOM   8602  C  CB  . VAL E 1 82  ? 51.405  124.308 77.793  1.00 41.05  ? 82  VAL E CB  1 
ATOM   8603  C  CG1 . VAL E 1 82  ? 51.815  125.774 77.841  1.00 36.23  ? 82  VAL E CG1 1 
ATOM   8604  C  CG2 . VAL E 1 82  ? 51.934  123.673 76.534  1.00 36.91  ? 82  VAL E CG2 1 
ATOM   8605  N  N   . GLN E 1 83  ? 50.218  124.200 80.665  1.00 41.72  ? 83  GLN E N   1 
ATOM   8606  C  CA  . GLN E 1 83  ? 49.652  124.969 81.769  1.00 41.93  ? 83  GLN E CA  1 
ATOM   8607  C  C   . GLN E 1 83  ? 50.322  124.603 83.088  1.00 41.64  ? 83  GLN E C   1 
ATOM   8608  O  O   . GLN E 1 83  ? 50.793  125.478 83.825  1.00 41.95  ? 83  GLN E O   1 
ATOM   8609  C  CB  . GLN E 1 83  ? 48.137  124.736 81.852  1.00 41.79  ? 83  GLN E CB  1 
ATOM   8610  C  CG  . GLN E 1 83  ? 47.318  125.268 80.663  1.00 43.96  ? 83  GLN E CG  1 
ATOM   8611  C  CD  . GLN E 1 83  ? 47.585  124.524 79.343  1.00 47.81  ? 83  GLN E CD  1 
ATOM   8612  O  OE1 . GLN E 1 83  ? 47.793  123.307 79.330  1.00 42.02  ? 83  GLN E OE1 1 
ATOM   8613  N  NE2 . GLN E 1 83  ? 47.580  125.262 78.234  1.00 45.12  ? 83  GLN E NE2 1 
ATOM   8614  N  N   . ALA E 1 84  ? 50.379  123.306 83.400  1.00 41.20  ? 84  ALA E N   1 
ATOM   8615  C  CA  . ALA E 1 84  ? 50.991  122.870 84.650  1.00 37.88  ? 84  ALA E CA  1 
ATOM   8616  C  C   . ALA E 1 84  ? 52.463  123.258 84.720  1.00 40.49  ? 84  ALA E C   1 
ATOM   8617  O  O   . ALA E 1 84  ? 52.975  123.580 85.795  1.00 43.69  ? 84  ALA E O   1 
ATOM   8618  C  CB  . ALA E 1 84  ? 50.821  121.365 84.812  1.00 39.14  ? 84  ALA E CB  1 
ATOM   8619  N  N   . LEU E 1 85  ? 53.163  123.253 83.586  1.00 41.03  ? 85  LEU E N   1 
ATOM   8620  C  CA  . LEU E 1 85  ? 54.560  123.677 83.624  1.00 40.89  ? 85  LEU E CA  1 
ATOM   8621  C  C   . LEU E 1 85  ? 54.670  125.190 83.717  1.00 41.01  ? 85  LEU E C   1 
ATOM   8622  O  O   . LEU E 1 85  ? 55.614  125.715 84.321  1.00 41.78  ? 85  LEU E O   1 
ATOM   8623  C  CB  . LEU E 1 85  ? 55.314  123.174 82.397  1.00 38.70  ? 85  LEU E CB  1 
ATOM   8624  C  CG  . LEU E 1 85  ? 55.658  121.679 82.343  1.00 36.68  ? 85  LEU E CG  1 
ATOM   8625  C  CD1 . LEU E 1 85  ? 56.380  121.376 81.043  1.00 33.73  ? 85  LEU E CD1 1 
ATOM   8626  C  CD2 . LEU E 1 85  ? 56.478  121.242 83.537  1.00 36.95  ? 85  LEU E CD2 1 
ATOM   8627  N  N   . LYS E 1 86  ? 53.733  125.902 83.099  1.00 38.75  ? 86  LYS E N   1 
ATOM   8628  C  CA  . LYS E 1 86  ? 53.694  127.347 83.255  1.00 43.79  ? 86  LYS E CA  1 
ATOM   8629  C  C   . LYS E 1 86  ? 53.465  127.716 84.715  1.00 41.05  ? 86  LYS E C   1 
ATOM   8630  O  O   . LYS E 1 86  ? 54.216  128.507 85.290  1.00 39.50  ? 86  LYS E O   1 
ATOM   8631  C  CB  . LYS E 1 86  ? 52.610  127.934 82.352  1.00 42.65  ? 86  LYS E CB  1 
ATOM   8632  C  CG  . LYS E 1 86  ? 52.587  129.433 82.317  1.00 39.28  ? 86  LYS E CG  1 
ATOM   8633  C  CD  . LYS E 1 86  ? 53.057  129.954 80.981  1.00 45.68  ? 86  LYS E CD  1 
ATOM   8634  C  CE  . LYS E 1 86  ? 52.942  131.472 80.932  1.00 42.55  ? 86  LYS E CE  1 
ATOM   8635  N  NZ  . LYS E 1 86  ? 53.635  132.007 79.751  1.00 41.84  ? 86  LYS E NZ  1 
ATOM   8636  N  N   . ALA E 1 87  ? 52.476  127.087 85.352  1.00 41.08  ? 87  ALA E N   1 
ATOM   8637  C  CA  . ALA E 1 87  ? 52.209  127.316 86.768  1.00 45.93  ? 87  ALA E CA  1 
ATOM   8638  C  C   . ALA E 1 87  ? 53.320  126.803 87.677  1.00 46.79  ? 87  ALA E C   1 
ATOM   8639  O  O   . ALA E 1 87  ? 53.266  127.038 88.888  1.00 48.61  ? 87  ALA E O   1 
ATOM   8640  C  CB  . ALA E 1 87  ? 50.882  126.660 87.168  1.00 31.64  ? 87  ALA E CB  1 
ATOM   8641  N  N   . PHE E 1 88  ? 54.312  126.104 87.139  1.00 45.44  ? 88  PHE E N   1 
ATOM   8642  C  CA  . PHE E 1 88  ? 55.385  125.542 87.946  1.00 39.15  ? 88  PHE E CA  1 
ATOM   8643  C  C   . PHE E 1 88  ? 56.661  126.372 87.868  1.00 40.27  ? 88  PHE E C   1 
ATOM   8644  O  O   . PHE E 1 88  ? 57.609  126.111 88.616  1.00 38.60  ? 88  PHE E O   1 
ATOM   8645  C  CB  . PHE E 1 88  ? 55.634  124.091 87.497  1.00 39.43  ? 88  PHE E CB  1 
ATOM   8646  C  CG  . PHE E 1 88  ? 56.660  123.357 88.305  1.00 44.45  ? 88  PHE E CG  1 
ATOM   8647  C  CD1 . PHE E 1 88  ? 56.349  122.867 89.562  1.00 42.83  ? 88  PHE E CD1 1 
ATOM   8648  C  CD2 . PHE E 1 88  ? 57.925  123.108 87.785  1.00 44.30  ? 88  PHE E CD2 1 
ATOM   8649  C  CE1 . PHE E 1 88  ? 57.291  122.169 90.307  1.00 47.41  ? 88  PHE E CE1 1 
ATOM   8650  C  CE2 . PHE E 1 88  ? 58.873  122.410 88.519  1.00 40.93  ? 88  PHE E CE2 1 
ATOM   8651  C  CZ  . PHE E 1 88  ? 58.557  121.940 89.783  1.00 48.76  ? 88  PHE E CZ  1 
ATOM   8652  N  N   . GLY E 1 89  ? 56.697  127.378 86.997  1.00 37.54  ? 89  GLY E N   1 
ATOM   8653  C  CA  . GLY E 1 89  ? 57.900  128.151 86.764  1.00 36.02  ? 89  GLY E CA  1 
ATOM   8654  C  C   . GLY E 1 89  ? 58.601  127.847 85.456  1.00 40.75  ? 89  GLY E C   1 
ATOM   8655  O  O   . GLY E 1 89  ? 59.572  128.541 85.120  1.00 35.84  ? 89  GLY E O   1 
ATOM   8656  N  N   . ILE E 1 90  ? 58.142  126.843 84.703  1.00 39.66  ? 90  ILE E N   1 
ATOM   8657  C  CA  . ILE E 1 90  ? 58.778  126.422 83.456  1.00 40.64  ? 90  ILE E CA  1 
ATOM   8658  C  C   . ILE E 1 90  ? 58.026  127.053 82.289  1.00 38.02  ? 90  ILE E C   1 
ATOM   8659  O  O   . ILE E 1 90  ? 56.873  126.703 82.019  1.00 37.75  ? 90  ILE E O   1 
ATOM   8660  C  CB  . ILE E 1 90  ? 58.814  124.892 83.321  1.00 36.53  ? 90  ILE E CB  1 
ATOM   8661  C  CG1 . ILE E 1 90  ? 59.443  124.252 84.550  1.00 35.11  ? 90  ILE E CG1 1 
ATOM   8662  C  CG2 . ILE E 1 90  ? 59.585  124.492 82.057  1.00 37.71  ? 90  ILE E CG2 1 
ATOM   8663  C  CD1 . ILE E 1 90  ? 60.855  124.661 84.766  1.00 36.74  ? 90  ILE E CD1 1 
ATOM   8664  N  N   . GLU E 1 91  ? 58.686  127.968 81.573  1.00 33.48  ? 91  GLU E N   1 
ATOM   8665  C  CA  . GLU E 1 91  ? 58.087  128.532 80.373  1.00 37.65  ? 91  GLU E CA  1 
ATOM   8666  C  C   . GLU E 1 91  ? 58.262  127.575 79.191  1.00 39.90  ? 91  GLU E C   1 
ATOM   8667  O  O   . GLU E 1 91  ? 59.262  126.854 79.116  1.00 36.83  ? 91  GLU E O   1 
ATOM   8668  C  CB  . GLU E 1 91  ? 58.728  129.882 80.033  1.00 39.98  ? 91  GLU E CB  1 
ATOM   8669  C  CG  . GLU E 1 91  ? 58.269  131.051 80.918  1.00 41.65  ? 91  GLU E CG  1 
ATOM   8670  C  CD  . GLU E 1 91  ? 56.824  131.419 80.680  1.00 38.12  ? 91  GLU E CD  1 
ATOM   8671  O  OE1 . GLU E 1 91  ? 56.520  131.988 79.612  1.00 40.92  ? 91  GLU E OE1 1 
ATOM   8672  O  OE2 . GLU E 1 91  ? 55.985  131.115 81.552  1.00 37.76  ? 91  GLU E OE2 1 
ATOM   8673  N  N   . PRO E 1 92  ? 57.321  127.585 78.234  1.00 38.71  ? 92  PRO E N   1 
ATOM   8674  C  CA  . PRO E 1 92  ? 57.428  126.669 77.085  1.00 35.95  ? 92  PRO E CA  1 
ATOM   8675  C  C   . PRO E 1 92  ? 58.756  126.758 76.363  1.00 38.57  ? 92  PRO E C   1 
ATOM   8676  O  O   . PRO E 1 92  ? 59.299  125.737 75.921  1.00 35.66  ? 92  PRO E O   1 
ATOM   8677  C  CB  . PRO E 1 92  ? 56.270  127.113 76.186  1.00 40.66  ? 92  PRO E CB  1 
ATOM   8678  C  CG  . PRO E 1 92  ? 55.271  127.705 77.134  1.00 45.72  ? 92  PRO E CG  1 
ATOM   8679  C  CD  . PRO E 1 92  ? 56.113  128.428 78.152  1.00 42.54  ? 92  PRO E CD  1 
ATOM   8680  N  N   . ALA E 1 93  ? 59.304  127.964 76.242  1.00 36.04  ? 93  ALA E N   1 
ATOM   8681  C  CA  . ALA E 1 93  ? 60.595  128.126 75.599  1.00 35.79  ? 93  ALA E CA  1 
ATOM   8682  C  C   . ALA E 1 93  ? 61.720  127.499 76.407  1.00 36.06  ? 93  ALA E C   1 
ATOM   8683  O  O   . ALA E 1 93  ? 62.817  127.306 75.869  1.00 33.22  ? 93  ALA E O   1 
ATOM   8684  C  CB  . ALA E 1 93  ? 60.877  129.614 75.371  1.00 41.24  ? 93  ALA E CB  1 
ATOM   8685  N  N   . ASP E 1 94  ? 61.474  127.182 77.678  1.00 35.86  ? 94  ASP E N   1 
ATOM   8686  C  CA  . ASP E 1 94  ? 62.483  126.647 78.590  1.00 36.41  ? 94  ASP E CA  1 
ATOM   8687  C  C   . ASP E 1 94  ? 62.396  125.124 78.688  1.00 36.15  ? 94  ASP E C   1 
ATOM   8688  O  O   . ASP E 1 94  ? 62.484  124.548 79.778  1.00 30.92  ? 94  ASP E O   1 
ATOM   8689  C  CB  . ASP E 1 94  ? 62.335  127.298 79.968  1.00 35.88  ? 94  ASP E CB  1 
ATOM   8690  C  CG  . ASP E 1 94  ? 63.580  127.131 80.851  1.00 40.07  ? 94  ASP E CG  1 
ATOM   8691  O  OD1 . ASP E 1 94  ? 64.707  127.059 80.307  1.00 42.52  ? 94  ASP E OD1 1 
ATOM   8692  O  OD2 . ASP E 1 94  ? 63.430  127.082 82.091  1.00 40.72  ? 94  ASP E OD2 1 
ATOM   8693  N  N   . VAL E 1 95  ? 62.198  124.446 77.559  1.00 33.31  ? 95  VAL E N   1 
ATOM   8694  C  CA  . VAL E 1 95  ? 62.220  122.986 77.494  1.00 30.10  ? 95  VAL E CA  1 
ATOM   8695  C  C   . VAL E 1 95  ? 63.140  122.601 76.346  1.00 32.40  ? 95  VAL E C   1 
ATOM   8696  O  O   . VAL E 1 95  ? 62.926  123.031 75.207  1.00 32.43  ? 95  VAL E O   1 
ATOM   8697  C  CB  . VAL E 1 95  ? 60.818  122.384 77.302  1.00 34.54  ? 95  VAL E CB  1 
ATOM   8698  C  CG1 . VAL E 1 95  ? 60.912  120.910 76.953  1.00 31.67  ? 95  VAL E CG1 1 
ATOM   8699  C  CG2 . VAL E 1 95  ? 59.982  122.596 78.565  1.00 31.07  ? 95  VAL E CG2 1 
ATOM   8700  N  N   . ARG E 1 96  ? 64.186  121.833 76.650  1.00 30.40  ? 96  ARG E N   1 
ATOM   8701  C  CA  . ARG E 1 96  ? 65.159  121.503 75.615  1.00 28.98  ? 96  ARG E CA  1 
ATOM   8702  C  C   . ARG E 1 96  ? 64.726  120.286 74.797  1.00 27.22  ? 96  ARG E C   1 
ATOM   8703  O  O   . ARG E 1 96  ? 64.888  120.269 73.582  1.00 25.88  ? 96  ARG E O   1 
ATOM   8704  C  CB  . ARG E 1 96  ? 66.531  121.265 76.243  1.00 26.31  ? 96  ARG E CB  1 
ATOM   8705  C  CG  . ARG E 1 96  ? 67.661  121.206 75.222  1.00 28.67  ? 96  ARG E CG  1 
ATOM   8706  C  CD  . ARG E 1 96  ? 69.013  121.128 75.903  1.00 26.89  ? 96  ARG E CD  1 
ATOM   8707  N  NE  . ARG E 1 96  ? 70.080  120.816 74.960  1.00 33.57  ? 96  ARG E NE  1 
ATOM   8708  C  CZ  . ARG E 1 96  ? 71.364  120.783 75.289  1.00 33.29  ? 96  ARG E CZ  1 
ATOM   8709  N  NH1 . ARG E 1 96  ? 71.766  121.020 76.532  1.00 30.38  ? 96  ARG E NH1 1 
ATOM   8710  N  NH2 . ARG E 1 96  ? 72.269  120.526 74.347  1.00 32.77  ? 96  ARG E NH2 1 
ATOM   8711  N  N   . TYR E 1 97  ? 64.170  119.270 75.445  1.00 29.80  ? 97  TYR E N   1 
ATOM   8712  C  CA  . TYR E 1 97  ? 63.826  118.015 74.794  1.00 28.41  ? 97  TYR E CA  1 
ATOM   8713  C  C   . TYR E 1 97  ? 62.417  117.600 75.175  1.00 27.26  ? 97  TYR E C   1 
ATOM   8714  O  O   . TYR E 1 97  ? 62.017  117.721 76.342  1.00 25.42  ? 97  TYR E O   1 
ATOM   8715  C  CB  . TYR E 1 97  ? 64.790  116.895 75.199  1.00 23.96  ? 97  TYR E CB  1 
ATOM   8716  C  CG  . TYR E 1 97  ? 66.216  117.156 74.807  1.00 26.28  ? 97  TYR E CG  1 
ATOM   8717  C  CD1 . TYR E 1 97  ? 66.587  117.209 73.461  1.00 26.50  ? 97  TYR E CD1 1 
ATOM   8718  C  CD2 . TYR E 1 97  ? 67.199  117.353 75.775  1.00 25.07  ? 97  TYR E CD2 1 
ATOM   8719  C  CE1 . TYR E 1 97  ? 67.909  117.458 73.088  1.00 27.36  ? 97  TYR E CE1 1 
ATOM   8720  C  CE2 . TYR E 1 97  ? 68.539  117.585 75.410  1.00 23.68  ? 97  TYR E CE2 1 
ATOM   8721  C  CZ  . TYR E 1 97  ? 68.882  117.628 74.065  1.00 27.54  ? 97  TYR E CZ  1 
ATOM   8722  O  OH  . TYR E 1 97  ? 70.192  117.858 73.673  1.00 29.79  ? 97  TYR E OH  1 
ATOM   8723  N  N   . VAL E 1 98  ? 61.679  117.101 74.189  1.00 25.36  ? 98  VAL E N   1 
ATOM   8724  C  CA  . VAL E 1 98  ? 60.491  116.280 74.418  1.00 26.79  ? 98  VAL E CA  1 
ATOM   8725  C  C   . VAL E 1 98  ? 60.821  114.848 73.983  1.00 24.66  ? 98  VAL E C   1 
ATOM   8726  O  O   . VAL E 1 98  ? 61.153  114.610 72.815  1.00 25.83  ? 98  VAL E O   1 
ATOM   8727  C  CB  . VAL E 1 98  ? 59.267  116.811 73.650  1.00 23.73  ? 98  VAL E CB  1 
ATOM   8728  C  CG1 . VAL E 1 98  ? 58.113  115.821 73.741  1.00 25.41  ? 98  VAL E CG1 1 
ATOM   8729  C  CG2 . VAL E 1 98  ? 58.842  118.178 74.160  1.00 29.29  ? 98  VAL E CG2 1 
ATOM   8730  N  N   . LEU E 1 99  ? 60.702  113.897 74.905  1.00 25.61  ? 99  LEU E N   1 
ATOM   8731  C  CA  . LEU E 1 99  ? 60.922  112.480 74.626  1.00 25.27  ? 99  LEU E CA  1 
ATOM   8732  C  C   . LEU E 1 99  ? 59.585  111.758 74.504  1.00 29.05  ? 99  LEU E C   1 
ATOM   8733  O  O   . LEU E 1 99  ? 58.686  111.962 75.329  1.00 25.80  ? 99  LEU E O   1 
ATOM   8734  C  CB  . LEU E 1 99  ? 61.729  111.824 75.743  1.00 22.57  ? 99  LEU E CB  1 
ATOM   8735  C  CG  . LEU E 1 99  ? 62.988  112.497 76.294  1.00 20.86  ? 99  LEU E CG  1 
ATOM   8736  C  CD1 . LEU E 1 99  ? 63.674  111.533 77.268  1.00 23.57  ? 99  LEU E CD1 1 
ATOM   8737  C  CD2 . LEU E 1 99  ? 63.936  112.911 75.199  1.00 21.17  ? 99  LEU E CD2 1 
ATOM   8738  N  N   . HIS E 1 100 ? 59.455  110.887 73.498  1.00 23.87  ? 100 HIS E N   1 
ATOM   8739  C  CA  . HIS E 1 100 ? 58.219  110.129 73.329  1.00 22.63  ? 100 HIS E CA  1 
ATOM   8740  C  C   . HIS E 1 100 ? 58.465  108.637 73.520  1.00 26.07  ? 100 HIS E C   1 
ATOM   8741  O  O   . HIS E 1 100 ? 59.267  108.036 72.796  1.00 23.80  ? 100 HIS E O   1 
ATOM   8742  C  CB  . HIS E 1 100 ? 57.583  110.429 71.972  1.00 20.13  ? 100 HIS E CB  1 
ATOM   8743  C  CG  . HIS E 1 100 ? 56.830  111.721 71.958  1.00 25.98  ? 100 HIS E CG  1 
ATOM   8744  N  ND1 . HIS E 1 100 ? 55.739  111.951 72.772  1.00 22.90  ? 100 HIS E ND1 1 
ATOM   8745  C  CD2 . HIS E 1 100 ? 57.050  112.877 71.284  1.00 23.26  ? 100 HIS E CD2 1 
ATOM   8746  C  CE1 . HIS E 1 100 ? 55.299  113.179 72.568  1.00 24.76  ? 100 HIS E CE1 1 
ATOM   8747  N  NE2 . HIS E 1 100 ? 56.063  113.755 71.655  1.00 22.58  ? 100 HIS E NE2 1 
ATOM   8748  N  N   . SER E 1 101 ? 57.786  108.052 74.512  1.00 23.08  ? 101 SER E N   1 
ATOM   8749  C  CA  . SER E 1 101 ? 57.703  106.598 74.615  1.00 23.85  ? 101 SER E CA  1 
ATOM   8750  C  C   . SER E 1 101 ? 57.082  106.011 73.356  1.00 25.07  ? 101 SER E C   1 
ATOM   8751  O  O   . SER E 1 101 ? 57.585  105.029 72.796  1.00 24.09  ? 101 SER E O   1 
ATOM   8752  C  CB  . SER E 1 101 ? 56.865  106.207 75.841  1.00 26.56  ? 101 SER E CB  1 
ATOM   8753  O  OG  . SER E 1 101 ? 55.491  106.511 75.621  1.00 28.74  ? 101 SER E OG  1 
ATOM   8754  N  N   . HIS E 1 102 ? 55.973  106.601 72.909  1.00 24.26  ? 102 HIS E N   1 
ATOM   8755  C  CA  . HIS E 1 102 ? 55.291  106.252 71.664  1.00 25.16  ? 102 HIS E CA  1 
ATOM   8756  C  C   . HIS E 1 102 ? 54.350  107.405 71.339  1.00 28.56  ? 102 HIS E C   1 
ATOM   8757  O  O   . HIS E 1 102 ? 54.260  108.384 72.091  1.00 28.07  ? 102 HIS E O   1 
ATOM   8758  C  CB  . HIS E 1 102 ? 54.566  104.905 71.756  1.00 23.49  ? 102 HIS E CB  1 
ATOM   8759  C  CG  . HIS E 1 102 ? 53.592  104.801 72.893  1.00 28.10  ? 102 HIS E CG  1 
ATOM   8760  N  ND1 . HIS E 1 102 ? 53.867  105.263 74.166  1.00 28.81  ? 102 HIS E ND1 1 
ATOM   8761  C  CD2 . HIS E 1 102 ? 52.363  104.232 72.957  1.00 25.91  ? 102 HIS E CD2 1 
ATOM   8762  C  CE1 . HIS E 1 102 ? 52.840  104.997 74.956  1.00 28.01  ? 102 HIS E CE1 1 
ATOM   8763  N  NE2 . HIS E 1 102 ? 51.920  104.365 74.250  1.00 28.78  ? 102 HIS E NE2 1 
ATOM   8764  N  N   . LEU E 1 103 ? 53.652  107.301 70.206  1.00 20.51  ? 103 LEU E N   1 
ATOM   8765  C  CA  . LEU E 1 103 ? 52.797  108.402 69.781  1.00 22.79  ? 103 LEU E CA  1 
ATOM   8766  C  C   . LEU E 1 103 ? 51.302  108.107 69.929  1.00 20.89  ? 103 LEU E C   1 
ATOM   8767  O  O   . LEU E 1 103 ? 50.481  108.671 69.204  1.00 25.25  ? 103 LEU E O   1 
ATOM   8768  C  CB  . LEU E 1 103 ? 53.139  108.819 68.358  1.00 22.43  ? 103 LEU E CB  1 
ATOM   8769  C  CG  . LEU E 1 103 ? 54.570  109.342 68.298  1.00 23.81  ? 103 LEU E CG  1 
ATOM   8770  C  CD1 . LEU E 1 103 ? 55.019  109.428 66.840  1.00 22.26  ? 103 LEU E CD1 1 
ATOM   8771  C  CD2 . LEU E 1 103 ? 54.690  110.718 69.010  1.00 22.62  ? 103 LEU E CD2 1 
ATOM   8772  N  N   . HIS E 1 104 ? 50.929  107.284 70.903  1.00 22.15  ? 104 HIS E N   1 
ATOM   8773  C  CA  . HIS E 1 104 ? 49.510  107.092 71.188  1.00 25.70  ? 104 HIS E CA  1 
ATOM   8774  C  C   . HIS E 1 104 ? 48.913  108.359 71.793  1.00 29.70  ? 104 HIS E C   1 
ATOM   8775  O  O   . HIS E 1 104 ? 49.620  109.235 72.312  1.00 28.45  ? 104 HIS E O   1 
ATOM   8776  C  CB  . HIS E 1 104 ? 49.282  105.915 72.139  1.00 25.24  ? 104 HIS E CB  1 
ATOM   8777  C  CG  . HIS E 1 104 ? 49.362  104.575 71.478  1.00 27.80  ? 104 HIS E CG  1 
ATOM   8778  N  ND1 . HIS E 1 104 ? 49.386  103.396 72.190  1.00 25.85  ? 104 HIS E ND1 1 
ATOM   8779  C  CD2 . HIS E 1 104 ? 49.451  104.226 70.169  1.00 24.92  ? 104 HIS E CD2 1 
ATOM   8780  C  CE1 . HIS E 1 104 ? 49.462  102.378 71.351  1.00 30.36  ? 104 HIS E CE1 1 
ATOM   8781  N  NE2 . HIS E 1 104 ? 49.508  102.856 70.118  1.00 28.56  ? 104 HIS E NE2 1 
ATOM   8782  N  N   . LEU E 1 105 ? 47.582  108.418 71.760  1.00 29.13  ? 105 LEU E N   1 
ATOM   8783  C  CA  . LEU E 1 105 ? 46.860  109.653 72.044  1.00 29.92  ? 105 LEU E CA  1 
ATOM   8784  C  C   . LEU E 1 105 ? 47.097  110.175 73.463  1.00 31.43  ? 105 LEU E C   1 
ATOM   8785  O  O   . LEU E 1 105 ? 47.091  111.392 73.677  1.00 32.05  ? 105 LEU E O   1 
ATOM   8786  C  CB  . LEU E 1 105 ? 45.367  109.437 71.793  1.00 30.20  ? 105 LEU E CB  1 
ATOM   8787  C  CG  . LEU E 1 105 ? 44.535  108.586 72.747  1.00 29.73  ? 105 LEU E CG  1 
ATOM   8788  C  CD1 . LEU E 1 105 ? 43.141  108.539 72.166  1.00 32.54  ? 105 LEU E CD1 1 
ATOM   8789  C  CD2 . LEU E 1 105 ? 45.076  107.158 72.949  1.00 26.63  ? 105 LEU E CD2 1 
ATOM   8790  N  N   . ASP E 1 106 ? 47.278  109.299 74.448  1.00 30.92  ? 106 ASP E N   1 
ATOM   8791  C  CA  . ASP E 1 106 ? 47.540  109.771 75.800  1.00 28.36  ? 106 ASP E CA  1 
ATOM   8792  C  C   . ASP E 1 106 ? 49.031  109.995 76.064  1.00 27.17  ? 106 ASP E C   1 
ATOM   8793  O  O   . ASP E 1 106 ? 49.461  109.976 77.223  1.00 29.69  ? 106 ASP E O   1 
ATOM   8794  C  CB  . ASP E 1 106 ? 46.930  108.807 76.813  1.00 31.83  ? 106 ASP E CB  1 
ATOM   8795  C  CG  . ASP E 1 106 ? 47.397  107.368 76.623  1.00 35.21  ? 106 ASP E CG  1 
ATOM   8796  O  OD1 . ASP E 1 106 ? 47.386  106.883 75.480  1.00 33.31  ? 106 ASP E OD1 1 
ATOM   8797  O  OD2 . ASP E 1 106 ? 47.729  106.707 77.633  1.00 32.13  ? 106 ASP E OD2 1 
ATOM   8798  N  N   . HIS E 1 107 ? 49.823  110.219 75.010  1.00 28.29  ? 107 HIS E N   1 
ATOM   8799  C  CA  . HIS E 1 107 ? 51.254  110.446 75.159  1.00 28.75  ? 107 HIS E CA  1 
ATOM   8800  C  C   . HIS E 1 107 ? 51.774  111.509 74.201  1.00 27.18  ? 107 HIS E C   1 
ATOM   8801  O  O   . HIS E 1 107 ? 52.999  111.680 74.099  1.00 28.71  ? 107 HIS E O   1 
ATOM   8802  C  CB  . HIS E 1 107 ? 52.043  109.145 74.955  1.00 28.11  ? 107 HIS E CB  1 
ATOM   8803  C  CG  . HIS E 1 107 ? 51.668  108.059 75.915  1.00 28.06  ? 107 HIS E CG  1 
ATOM   8804  N  ND1 . HIS E 1 107 ? 52.337  107.847 77.102  1.00 25.45  ? 107 HIS E ND1 1 
ATOM   8805  C  CD2 . HIS E 1 107 ? 50.672  107.146 75.877  1.00 27.68  ? 107 HIS E CD2 1 
ATOM   8806  C  CE1 . HIS E 1 107 ? 51.782  106.834 77.739  1.00 24.74  ? 107 HIS E CE1 1 
ATOM   8807  N  NE2 . HIS E 1 107 ? 50.765  106.399 77.022  1.00 28.79  ? 107 HIS E NE2 1 
ATOM   8808  N  N   . THR E 1 108 ? 50.895  112.224 73.494  1.00 24.92  ? 108 THR E N   1 
ATOM   8809  C  CA  . THR E 1 108 ? 51.311  113.259 72.553  1.00 29.61  ? 108 THR E CA  1 
ATOM   8810  C  C   . THR E 1 108 ? 50.772  114.642 72.937  1.00 31.51  ? 108 THR E C   1 
ATOM   8811  O  O   . THR E 1 108 ? 50.708  115.546 72.089  1.00 31.88  ? 108 THR E O   1 
ATOM   8812  C  CB  . THR E 1 108 ? 50.906  112.872 71.114  1.00 31.94  ? 108 THR E CB  1 
ATOM   8813  O  OG1 . THR E 1 108 ? 49.495  112.635 71.022  1.00 28.18  ? 108 THR E OG1 1 
ATOM   8814  C  CG2 . THR E 1 108 ? 51.623  111.601 70.702  1.00 26.18  ? 108 THR E CG2 1 
ATOM   8815  N  N   . GLY E 1 109 ? 50.406  114.834 74.211  1.00 31.78  ? 109 GLY E N   1 
ATOM   8816  C  CA  . GLY E 1 109 ? 49.982  116.154 74.668  1.00 34.40  ? 109 GLY E CA  1 
ATOM   8817  C  C   . GLY E 1 109 ? 51.063  117.216 74.565  1.00 33.30  ? 109 GLY E C   1 
ATOM   8818  O  O   . GLY E 1 109 ? 50.759  118.396 74.360  1.00 37.14  ? 109 GLY E O   1 
ATOM   8819  N  N   . ALA E 1 110 ? 52.336  116.822 74.691  1.00 32.07  ? 110 ALA E N   1 
ATOM   8820  C  CA  . ALA E 1 110 ? 53.440  117.773 74.642  1.00 30.58  ? 110 ALA E CA  1 
ATOM   8821  C  C   . ALA E 1 110 ? 53.925  118.086 73.231  1.00 32.90  ? 110 ALA E C   1 
ATOM   8822  O  O   . ALA E 1 110 ? 54.671  119.063 73.062  1.00 32.62  ? 110 ALA E O   1 
ATOM   8823  C  CB  . ALA E 1 110 ? 54.626  117.253 75.471  1.00 28.35  ? 110 ALA E CB  1 
ATOM   8824  N  N   . THR E 1 111 ? 53.537  117.287 72.226  1.00 28.66  ? 111 THR E N   1 
ATOM   8825  C  CA  . THR E 1 111 ? 54.142  117.384 70.897  1.00 29.07  ? 111 THR E CA  1 
ATOM   8826  C  C   . THR E 1 111 ? 53.879  118.752 70.262  1.00 29.81  ? 111 THR E C   1 
ATOM   8827  O  O   . THR E 1 111 ? 52.727  119.152 70.074  1.00 33.60  ? 111 THR E O   1 
ATOM   8828  C  CB  . THR E 1 111 ? 53.621  116.269 69.973  1.00 28.61  ? 111 THR E CB  1 
ATOM   8829  O  OG1 . THR E 1 111 ? 53.725  114.990 70.615  1.00 28.90  ? 111 THR E OG1 1 
ATOM   8830  C  CG2 . THR E 1 111 ? 54.449  116.223 68.702  1.00 29.93  ? 111 THR E CG2 1 
ATOM   8831  N  N   . GLY E 1 112 ? 54.951  119.454 69.907  1.00 29.19  ? 112 GLY E N   1 
ATOM   8832  C  CA  . GLY E 1 112 ? 54.840  120.746 69.263  1.00 32.80  ? 112 GLY E CA  1 
ATOM   8833  C  C   . GLY E 1 112 ? 54.400  121.900 70.150  1.00 37.01  ? 112 GLY E C   1 
ATOM   8834  O  O   . GLY E 1 112 ? 54.222  123.012 69.639  1.00 37.08  ? 112 GLY E O   1 
ATOM   8835  N  N   . ARG E 1 113 ? 54.199  121.677 71.447  1.00 33.26  ? 113 ARG E N   1 
ATOM   8836  C  CA  . ARG E 1 113 ? 53.796  122.733 72.368  1.00 38.61  ? 113 ARG E CA  1 
ATOM   8837  C  C   . ARG E 1 113 ? 54.979  123.427 73.016  1.00 39.79  ? 113 ARG E C   1 
ATOM   8838  O  O   . ARG E 1 113 ? 54.796  124.407 73.748  1.00 40.59  ? 113 ARG E O   1 
ATOM   8839  C  CB  . ARG E 1 113 ? 52.893  122.167 73.460  1.00 36.06  ? 113 ARG E CB  1 
ATOM   8840  C  CG  . ARG E 1 113 ? 51.443  122.114 73.055  1.00 41.13  ? 113 ARG E CG  1 
ATOM   8841  C  CD  . ARG E 1 113 ? 51.150  120.785 72.453  1.00 35.75  ? 113 ARG E CD  1 
ATOM   8842  N  NE  . ARG E 1 113 ? 49.731  120.466 72.477  1.00 36.78  ? 113 ARG E NE  1 
ATOM   8843  C  CZ  . ARG E 1 113 ? 49.219  119.378 71.922  1.00 43.90  ? 113 ARG E CZ  1 
ATOM   8844  N  NH1 . ARG E 1 113 ? 49.997  118.470 71.327  1.00 36.99  ? 113 ARG E NH1 1 
ATOM   8845  N  NH2 . ARG E 1 113 ? 47.903  119.185 71.976  1.00 41.08  ? 113 ARG E NH2 1 
ATOM   8846  N  N   . PHE E 1 114 ? 56.180  122.936 72.775  1.00 34.66  ? 114 PHE E N   1 
ATOM   8847  C  CA  . PHE E 1 114 ? 57.379  123.518 73.348  1.00 31.86  ? 114 PHE E CA  1 
ATOM   8848  C  C   . PHE E 1 114 ? 58.259  123.924 72.185  1.00 37.06  ? 114 PHE E C   1 
ATOM   8849  O  O   . PHE E 1 114 ? 58.898  123.070 71.544  1.00 37.75  ? 114 PHE E O   1 
ATOM   8850  C  CB  . PHE E 1 114 ? 58.039  122.526 74.293  1.00 33.75  ? 114 PHE E CB  1 
ATOM   8851  C  CG  . PHE E 1 114 ? 57.139  122.149 75.434  1.00 34.11  ? 114 PHE E CG  1 
ATOM   8852  C  CD1 . PHE E 1 114 ? 57.055  122.962 76.562  1.00 31.84  ? 114 PHE E CD1 1 
ATOM   8853  C  CD2 . PHE E 1 114 ? 56.312  121.035 75.350  1.00 29.60  ? 114 PHE E CD2 1 
ATOM   8854  C  CE1 . PHE E 1 114 ? 56.195  122.637 77.610  1.00 31.65  ? 114 PHE E CE1 1 
ATOM   8855  C  CE2 . PHE E 1 114 ? 55.450  120.702 76.387  1.00 30.74  ? 114 PHE E CE2 1 
ATOM   8856  C  CZ  . PHE E 1 114 ? 55.385  121.502 77.522  1.00 32.16  ? 114 PHE E CZ  1 
ATOM   8857  N  N   . PRO E 1 115 ? 58.309  125.222 71.874  1.00 38.75  ? 115 PRO E N   1 
ATOM   8858  C  CA  . PRO E 1 115 ? 58.785  125.660 70.554  1.00 34.77  ? 115 PRO E CA  1 
ATOM   8859  C  C   . PRO E 1 115 ? 60.276  125.520 70.338  1.00 34.75  ? 115 PRO E C   1 
ATOM   8860  O  O   . PRO E 1 115 ? 60.717  125.617 69.187  1.00 38.86  ? 115 PRO E O   1 
ATOM   8861  C  CB  . PRO E 1 115 ? 58.351  127.136 70.494  1.00 38.42  ? 115 PRO E CB  1 
ATOM   8862  C  CG  . PRO E 1 115 ? 58.112  127.556 71.925  1.00 38.42  ? 115 PRO E CG  1 
ATOM   8863  C  CD  . PRO E 1 115 ? 57.963  126.340 72.776  1.00 36.95  ? 115 PRO E CD  1 
ATOM   8864  N  N   . ASN E 1 116 ? 61.076  125.294 71.370  1.00 34.05  ? 116 ASN E N   1 
ATOM   8865  C  CA  . ASN E 1 116 ? 62.495  125.050 71.150  1.00 37.73  ? 116 ASN E CA  1 
ATOM   8866  C  C   . ASN E 1 116 ? 62.897  123.591 71.342  1.00 37.16  ? 116 ASN E C   1 
ATOM   8867  O  O   . ASN E 1 116 ? 64.079  123.267 71.191  1.00 40.40  ? 116 ASN E O   1 
ATOM   8868  C  CB  . ASN E 1 116 ? 63.348  125.929 72.073  1.00 31.53  ? 116 ASN E CB  1 
ATOM   8869  C  CG  . ASN E 1 116 ? 62.973  127.395 71.994  1.00 40.05  ? 116 ASN E CG  1 
ATOM   8870  O  OD1 . ASN E 1 116 ? 62.936  127.994 70.913  1.00 33.61  ? 116 ASN E OD1 1 
ATOM   8871  N  ND2 . ASN E 1 116 ? 62.723  127.990 73.148  1.00 39.98  ? 116 ASN E ND2 1 
ATOM   8872  N  N   . ALA E 1 117 ? 61.964  122.706 71.675  1.00 35.30  ? 117 ALA E N   1 
ATOM   8873  C  CA  . ALA E 1 117 ? 62.331  121.345 72.052  1.00 33.53  ? 117 ALA E CA  1 
ATOM   8874  C  C   . ALA E 1 117 ? 62.630  120.496 70.822  1.00 34.85  ? 117 ALA E C   1 
ATOM   8875  O  O   . ALA E 1 117 ? 61.881  120.527 69.839  1.00 32.77  ? 117 ALA E O   1 
ATOM   8876  C  CB  . ALA E 1 117 ? 61.218  120.699 72.870  1.00 32.43  ? 117 ALA E CB  1 
ATOM   8877  N  N   . ILE E 1 118 ? 63.734  119.751 70.872  1.00 32.57  ? 118 ILE E N   1 
ATOM   8878  C  CA  . ILE E 1 118 ? 63.928  118.644 69.943  1.00 31.32  ? 118 ILE E CA  1 
ATOM   8879  C  C   . ILE E 1 118 ? 63.101  117.464 70.431  1.00 30.62  ? 118 ILE E C   1 
ATOM   8880  O  O   . ILE E 1 118 ? 63.189  117.069 71.602  1.00 27.64  ? 118 ILE E O   1 
ATOM   8881  C  CB  . ILE E 1 118 ? 65.413  118.274 69.815  1.00 33.15  ? 118 ILE E CB  1 
ATOM   8882  C  CG1 . ILE E 1 118 ? 66.204  119.447 69.222  1.00 32.28  ? 118 ILE E CG1 1 
ATOM   8883  C  CG2 . ILE E 1 118 ? 65.571  117.020 68.956  1.00 33.14  ? 118 ILE E CG2 1 
ATOM   8884  C  CD1 . ILE E 1 118 ? 67.662  119.145 68.964  1.00 29.77  ? 118 ILE E CD1 1 
ATOM   8885  N  N   . HIS E 1 119 ? 62.266  116.924 69.544  1.00 30.39  ? 119 HIS E N   1 
ATOM   8886  C  CA  . HIS E 1 119 ? 61.406  115.787 69.858  1.00 28.48  ? 119 HIS E CA  1 
ATOM   8887  C  C   . HIS E 1 119 ? 62.107  114.489 69.472  1.00 27.03  ? 119 HIS E C   1 
ATOM   8888  O  O   . HIS E 1 119 ? 62.447  114.297 68.296  1.00 27.28  ? 119 HIS E O   1 
ATOM   8889  C  CB  . HIS E 1 119 ? 60.079  115.906 69.117  1.00 27.68  ? 119 HIS E CB  1 
ATOM   8890  C  CG  . HIS E 1 119 ? 59.184  116.975 69.662  1.00 31.73  ? 119 HIS E CG  1 
ATOM   8891  N  ND1 . HIS E 1 119 ? 59.513  118.312 69.615  1.00 29.99  ? 119 HIS E ND1 1 
ATOM   8892  C  CD2 . HIS E 1 119 ? 57.984  116.902 70.288  1.00 31.56  ? 119 HIS E CD2 1 
ATOM   8893  C  CE1 . HIS E 1 119 ? 58.544  119.020 70.172  1.00 34.60  ? 119 HIS E CE1 1 
ATOM   8894  N  NE2 . HIS E 1 119 ? 57.604  118.188 70.591  1.00 32.26  ? 119 HIS E NE2 1 
ATOM   8895  N  N   . ILE E 1 120 ? 62.300  113.595 70.445  1.00 23.17  ? 120 ILE E N   1 
ATOM   8896  C  CA  . ILE E 1 120 ? 63.050  112.355 70.249  1.00 26.63  ? 120 ILE E CA  1 
ATOM   8897  C  C   . ILE E 1 120 ? 62.114  111.160 70.394  1.00 25.69  ? 120 ILE E C   1 
ATOM   8898  O  O   . ILE E 1 120 ? 61.469  110.989 71.439  1.00 23.89  ? 120 ILE E O   1 
ATOM   8899  C  CB  . ILE E 1 120 ? 64.225  112.244 71.224  1.00 23.38  ? 120 ILE E CB  1 
ATOM   8900  C  CG1 . ILE E 1 120 ? 64.963  113.586 71.325  1.00 24.06  ? 120 ILE E CG1 1 
ATOM   8901  C  CG2 . ILE E 1 120 ? 65.175  111.132 70.766  1.00 24.83  ? 120 ILE E CG2 1 
ATOM   8902  C  CD1 . ILE E 1 120 ? 66.193  113.547 72.231  1.00 17.96  ? 120 ILE E CD1 1 
ATOM   8903  N  N   . VAL E 1 121 ? 62.073  110.323 69.353  1.00 21.59  ? 121 VAL E N   1 
ATOM   8904  C  CA  . VAL E 1 121 ? 61.239  109.121 69.320  1.00 23.33  ? 121 VAL E CA  1 
ATOM   8905  C  C   . VAL E 1 121 ? 61.863  108.136 68.334  1.00 21.71  ? 121 VAL E C   1 
ATOM   8906  O  O   . VAL E 1 121 ? 62.639  108.522 67.459  1.00 20.25  ? 121 VAL E O   1 
ATOM   8907  C  CB  . VAL E 1 121 ? 59.785  109.469 68.913  1.00 22.39  ? 121 VAL E CB  1 
ATOM   8908  C  CG1 . VAL E 1 121 ? 59.715  109.723 67.420  1.00 18.71  ? 121 VAL E CG1 1 
ATOM   8909  C  CG2 . VAL E 1 121 ? 58.829  108.361 69.309  1.00 18.65  ? 121 VAL E CG2 1 
ATOM   8910  N  N   . ARG E 1 122 ? 61.516  106.850 68.465  1.00 20.19  ? 122 ARG E N   1 
ATOM   8911  C  CA  . ARG E 1 122 ? 61.976  105.885 67.468  1.00 21.23  ? 122 ARG E CA  1 
ATOM   8912  C  C   . ARG E 1 122 ? 61.408  106.228 66.099  1.00 19.08  ? 122 ARG E C   1 
ATOM   8913  O  O   . ARG E 1 122 ? 60.225  106.537 65.962  1.00 19.16  ? 122 ARG E O   1 
ATOM   8914  C  CB  . ARG E 1 122 ? 61.572  104.459 67.853  1.00 17.35  ? 122 ARG E CB  1 
ATOM   8915  C  CG  . ARG E 1 122 ? 62.306  103.928 69.043  1.00 15.56  ? 122 ARG E CG  1 
ATOM   8916  C  CD  . ARG E 1 122 ? 62.229  102.417 69.055  1.00 21.85  ? 122 ARG E CD  1 
ATOM   8917  N  NE  . ARG E 1 122 ? 62.977  101.843 67.944  1.00 23.71  ? 122 ARG E NE  1 
ATOM   8918  C  CZ  . ARG E 1 122 ? 63.128  100.542 67.732  1.00 25.83  ? 122 ARG E CZ  1 
ATOM   8919  N  NH1 . ARG E 1 122 ? 62.511  99.643  68.480  1.00 20.50  ? 122 ARG E NH1 1 
ATOM   8920  N  NH2 . ARG E 1 122 ? 63.931  100.133 66.752  1.00 25.39  ? 122 ARG E NH2 1 
ATOM   8921  N  N   . ARG E 1 123 ? 62.260  106.165 65.074  1.00 23.35  ? 123 ARG E N   1 
ATOM   8922  C  CA  . ARG E 1 123 ? 61.760  106.364 63.718  1.00 20.75  ? 123 ARG E CA  1 
ATOM   8923  C  C   . ARG E 1 123 ? 60.558  105.477 63.427  1.00 19.67  ? 123 ARG E C   1 
ATOM   8924  O  O   . ARG E 1 123 ? 59.587  105.918 62.798  1.00 22.84  ? 123 ARG E O   1 
ATOM   8925  C  CB  . ARG E 1 123 ? 62.852  106.098 62.673  1.00 22.64  ? 123 ARG E CB  1 
ATOM   8926  C  CG  . ARG E 1 123 ? 62.278  106.029 61.254  1.00 21.38  ? 123 ARG E CG  1 
ATOM   8927  C  CD  . ARG E 1 123 ? 63.358  105.889 60.206  1.00 22.13  ? 123 ARG E CD  1 
ATOM   8928  N  NE  . ARG E 1 123 ? 64.188  107.081 60.174  1.00 28.63  ? 123 ARG E NE  1 
ATOM   8929  C  CZ  . ARG E 1 123 ? 63.839  108.231 59.609  1.00 29.55  ? 123 ARG E CZ  1 
ATOM   8930  N  NH1 . ARG E 1 123 ? 62.684  108.375 58.969  1.00 27.59  ? 123 ARG E NH1 1 
ATOM   8931  N  NH2 . ARG E 1 123 ? 64.681  109.255 59.660  1.00 32.95  ? 123 ARG E NH2 1 
ATOM   8932  N  N   . CYS E 1 124 ? 60.600  104.220 63.857  1.00 18.42  ? 124 CYS E N   1 
ATOM   8933  C  CA  . CYS E 1 124 ? 59.536  103.331 63.413  1.00 23.28  ? 124 CYS E CA  1 
ATOM   8934  C  C   . CYS E 1 124 ? 58.209  103.684 64.075  1.00 22.86  ? 124 CYS E C   1 
ATOM   8935  O  O   . CYS E 1 124 ? 57.151  103.443 63.487  1.00 23.93  ? 124 CYS E O   1 
ATOM   8936  C  CB  . CYS E 1 124 ? 59.908  101.860 63.641  1.00 24.81  ? 124 CYS E CB  1 
ATOM   8937  S  SG  . CYS E 1 124 ? 59.984  101.281 65.338  1.00 34.73  ? 124 CYS E SG  1 
ATOM   8938  N  N   . GLU E 1 125 ? 58.241  104.294 65.265  1.00 20.27  ? 125 GLU E N   1 
ATOM   8939  C  CA  . GLU E 1 125 ? 56.995  104.790 65.846  1.00 23.33  ? 125 GLU E CA  1 
ATOM   8940  C  C   . GLU E 1 125 ? 56.459  105.954 65.035  1.00 23.25  ? 125 GLU E C   1 
ATOM   8941  O  O   . GLU E 1 125 ? 55.258  106.023 64.749  1.00 22.55  ? 125 GLU E O   1 
ATOM   8942  C  CB  . GLU E 1 125 ? 57.192  105.220 67.307  1.00 17.29  ? 125 GLU E CB  1 
ATOM   8943  C  CG  . GLU E 1 125 ? 55.893  105.677 67.970  1.00 18.36  ? 125 GLU E CG  1 
ATOM   8944  C  CD  . GLU E 1 125 ? 54.906  104.525 68.160  1.00 22.20  ? 125 GLU E CD  1 
ATOM   8945  O  OE1 . GLU E 1 125 ? 55.280  103.341 67.961  1.00 23.25  ? 125 GLU E OE1 1 
ATOM   8946  O  OE2 . GLU E 1 125 ? 53.754  104.799 68.506  1.00 22.59  ? 125 GLU E OE2 1 
ATOM   8947  N  N   . TYR E 1 126 ? 57.340  106.872 64.649  1.00 19.97  ? 126 TYR E N   1 
ATOM   8948  C  CA  . TYR E 1 126 ? 56.890  108.016 63.878  1.00 22.58  ? 126 TYR E CA  1 
ATOM   8949  C  C   . TYR E 1 126 ? 56.295  107.565 62.555  1.00 23.62  ? 126 TYR E C   1 
ATOM   8950  O  O   . TYR E 1 126 ? 55.209  108.007 62.160  1.00 24.89  ? 126 TYR E O   1 
ATOM   8951  C  CB  . TYR E 1 126 ? 58.056  108.974 63.660  1.00 23.21  ? 126 TYR E CB  1 
ATOM   8952  C  CG  . TYR E 1 126 ? 57.723  110.134 62.764  1.00 26.18  ? 126 TYR E CG  1 
ATOM   8953  C  CD1 . TYR E 1 126 ? 57.216  111.317 63.283  1.00 27.01  ? 126 TYR E CD1 1 
ATOM   8954  C  CD2 . TYR E 1 126 ? 57.949  110.058 61.400  1.00 26.04  ? 126 TYR E CD2 1 
ATOM   8955  C  CE1 . TYR E 1 126 ? 56.924  112.404 62.446  1.00 34.73  ? 126 TYR E CE1 1 
ATOM   8956  C  CE2 . TYR E 1 126 ? 57.663  111.117 60.562  1.00 32.38  ? 126 TYR E CE2 1 
ATOM   8957  C  CZ  . TYR E 1 126 ? 57.153  112.292 61.082  1.00 35.75  ? 126 TYR E CZ  1 
ATOM   8958  O  OH  . TYR E 1 126 ? 56.874  113.341 60.224  1.00 37.26  ? 126 TYR E OH  1 
ATOM   8959  N  N   . GLU E 1 127 ? 56.984  106.659 61.870  1.00 21.32  ? 127 GLU E N   1 
ATOM   8960  C  CA  . GLU E 1 127 ? 56.475  106.175 60.594  1.00 24.00  ? 127 GLU E CA  1 
ATOM   8961  C  C   . GLU E 1 127 ? 55.164  105.421 60.772  1.00 23.62  ? 127 GLU E C   1 
ATOM   8962  O  O   . GLU E 1 127 ? 54.234  105.603 59.978  1.00 20.88  ? 127 GLU E O   1 
ATOM   8963  C  CB  . GLU E 1 127 ? 57.524  105.300 59.918  1.00 20.70  ? 127 GLU E CB  1 
ATOM   8964  C  CG  . GLU E 1 127 ? 58.747  106.121 59.511  1.00 23.17  ? 127 GLU E CG  1 
ATOM   8965  C  CD  . GLU E 1 127 ? 59.811  105.312 58.804  1.00 23.77  ? 127 GLU E CD  1 
ATOM   8966  O  OE1 . GLU E 1 127 ? 59.799  104.067 58.877  1.00 26.09  ? 127 GLU E OE1 1 
ATOM   8967  O  OE2 . GLU E 1 127 ? 60.657  105.934 58.152  1.00 29.35  ? 127 GLU E OE2 1 
ATOM   8968  N  N   . TYR E 1 128 ? 55.072  104.570 61.807  1.00 21.55  ? 128 TYR E N   1 
ATOM   8969  C  CA  . TYR E 1 128 ? 53.825  103.847 62.046  1.00 22.54  ? 128 TYR E CA  1 
ATOM   8970  C  C   . TYR E 1 128 ? 52.693  104.806 62.398  1.00 23.20  ? 128 TYR E C   1 
ATOM   8971  O  O   . TYR E 1 128 ? 51.552  104.606 61.972  1.00 23.67  ? 128 TYR E O   1 
ATOM   8972  C  CB  . TYR E 1 128 ? 53.984  102.802 63.154  1.00 22.27  ? 128 TYR E CB  1 
ATOM   8973  C  CG  . TYR E 1 128 ? 52.748  101.898 63.287  1.00 21.69  ? 128 TYR E CG  1 
ATOM   8974  C  CD1 . TYR E 1 128 ? 52.519  100.893 62.368  1.00 20.32  ? 128 TYR E CD1 1 
ATOM   8975  C  CD2 . TYR E 1 128 ? 51.794  102.089 64.301  1.00 23.48  ? 128 TYR E CD2 1 
ATOM   8976  C  CE1 . TYR E 1 128 ? 51.408  100.055 62.454  1.00 20.29  ? 128 TYR E CE1 1 
ATOM   8977  C  CE2 . TYR E 1 128 ? 50.645  101.252 64.402  1.00 20.97  ? 128 TYR E CE2 1 
ATOM   8978  C  CZ  . TYR E 1 128 ? 50.471  100.236 63.451  1.00 25.70  ? 128 TYR E CZ  1 
ATOM   8979  O  OH  . TYR E 1 128 ? 49.390  99.370  63.460  1.00 22.33  ? 128 TYR E OH  1 
ATOM   8980  N  N   . ALA E 1 129 ? 52.990  105.847 63.182  1.00 23.13  ? 129 ALA E N   1 
ATOM   8981  C  CA  . ALA E 1 129 ? 51.964  106.829 63.544  1.00 24.67  ? 129 ALA E CA  1 
ATOM   8982  C  C   . ALA E 1 129 ? 51.370  107.494 62.311  1.00 24.40  ? 129 ALA E C   1 
ATOM   8983  O  O   . ALA E 1 129 ? 50.165  107.750 62.263  1.00 23.96  ? 129 ALA E O   1 
ATOM   8984  C  CB  . ALA E 1 129 ? 52.543  107.885 64.483  1.00 22.58  ? 129 ALA E CB  1 
ATOM   8985  N  N   . MET E 1 130 ? 52.196  107.743 61.291  1.00 21.42  ? 130 MET E N   1 
ATOM   8986  C  CA  . MET E 1 130 ? 51.744  108.358 60.047  1.00 22.33  ? 130 MET E CA  1 
ATOM   8987  C  C   . MET E 1 130 ? 50.997  107.399 59.126  1.00 27.19  ? 130 MET E C   1 
ATOM   8988  O  O   . MET E 1 130 ? 50.294  107.858 58.227  1.00 28.06  ? 130 MET E O   1 
ATOM   8989  C  CB  . MET E 1 130 ? 52.944  108.953 59.288  1.00 28.22  ? 130 MET E CB  1 
ATOM   8990  C  CG  . MET E 1 130 ? 53.669  110.076 60.037  1.00 26.13  ? 130 MET E CG  1 
ATOM   8991  S  SD  . MET E 1 130 ? 52.647  111.567 60.176  1.00 37.17  ? 130 MET E SD  1 
ATOM   8992  C  CE  . MET E 1 130 ? 53.406  112.581 58.902  1.00 42.59  ? 130 MET E CE  1 
ATOM   8993  N  N   . ALA E 1 131 ? 51.141  106.087 59.303  1.00 28.76  ? 131 ALA E N   1 
ATOM   8994  C  CA  . ALA E 1 131 ? 50.462  105.100 58.458  1.00 26.58  ? 131 ALA E CA  1 
ATOM   8995  C  C   . ALA E 1 131 ? 50.076  103.894 59.303  1.00 26.56  ? 131 ALA E C   1 
ATOM   8996  O  O   . ALA E 1 131 ? 50.649  102.806 59.171  1.00 23.08  ? 131 ALA E O   1 
ATOM   8997  C  CB  . ALA E 1 131 ? 51.350  104.697 57.278  1.00 25.08  ? 131 ALA E CB  1 
ATOM   8998  N  N   . PRO E 1 132 ? 49.111  104.060 60.206  1.00 26.77  ? 132 PRO E N   1 
ATOM   8999  C  CA  . PRO E 1 132 ? 48.719  102.954 61.081  1.00 23.77  ? 132 PRO E CA  1 
ATOM   9000  C  C   . PRO E 1 132 ? 47.725  102.035 60.394  1.00 19.39  ? 132 PRO E C   1 
ATOM   9001  O  O   . PRO E 1 132 ? 47.133  102.371 59.373  1.00 24.81  ? 132 PRO E O   1 
ATOM   9002  C  CB  . PRO E 1 132 ? 48.081  103.669 62.275  1.00 26.07  ? 132 PRO E CB  1 
ATOM   9003  C  CG  . PRO E 1 132 ? 47.454  104.885 61.634  1.00 26.95  ? 132 PRO E CG  1 
ATOM   9004  C  CD  . PRO E 1 132 ? 48.400  105.306 60.537  1.00 23.17  ? 132 PRO E CD  1 
ATOM   9005  N  N   . ASP E 1 133 ? 47.590  100.842 60.956  1.00 22.80  ? 133 ASP E N   1 
ATOM   9006  C  CA  . ASP E 1 133 ? 46.594  99.883  60.503  1.00 23.35  ? 133 ASP E CA  1 
ATOM   9007  C  C   . ASP E 1 133 ? 45.232  100.253 61.091  1.00 23.28  ? 133 ASP E C   1 
ATOM   9008  O  O   . ASP E 1 133 ? 45.133  101.073 62.005  1.00 28.22  ? 133 ASP E O   1 
ATOM   9009  C  CB  . ASP E 1 133 ? 46.997  98.461  60.910  1.00 21.06  ? 133 ASP E CB  1 
ATOM   9010  C  CG  . ASP E 1 133 ? 48.310  98.021  60.285  1.00 24.70  ? 133 ASP E CG  1 
ATOM   9011  O  OD1 . ASP E 1 133 ? 48.305  97.723  59.070  1.00 25.86  ? 133 ASP E OD1 1 
ATOM   9012  O  OD2 . ASP E 1 133 ? 49.344  97.965  61.000  1.00 23.92  ? 133 ASP E OD2 1 
ATOM   9013  N  N   . TRP E 1 134 ? 44.171  99.620  60.583  1.00 22.82  ? 134 TRP E N   1 
ATOM   9014  C  CA  . TRP E 1 134 ? 42.821  100.049 60.956  1.00 25.23  ? 134 TRP E CA  1 
ATOM   9015  C  C   . TRP E 1 134 ? 42.577  99.922  62.460  1.00 26.85  ? 134 TRP E C   1 
ATOM   9016  O  O   . TRP E 1 134 ? 41.957  100.801 63.064  1.00 26.61  ? 134 TRP E O   1 
ATOM   9017  C  CB  . TRP E 1 134 ? 41.769  99.281  60.153  1.00 28.32  ? 134 TRP E CB  1 
ATOM   9018  C  CG  . TRP E 1 134 ? 41.674  97.812  60.457  1.00 28.17  ? 134 TRP E CG  1 
ATOM   9019  C  CD1 . TRP E 1 134 ? 42.191  96.796  59.709  1.00 27.32  ? 134 TRP E CD1 1 
ATOM   9020  C  CD2 . TRP E 1 134 ? 40.985  97.189  61.561  1.00 30.75  ? 134 TRP E CD2 1 
ATOM   9021  N  NE1 . TRP E 1 134 ? 41.889  95.579  60.286  1.00 28.73  ? 134 TRP E NE1 1 
ATOM   9022  C  CE2 . TRP E 1 134 ? 41.156  95.791  61.425  1.00 26.29  ? 134 TRP E CE2 1 
ATOM   9023  C  CE3 . TRP E 1 134 ? 40.240  97.676  62.651  1.00 30.12  ? 134 TRP E CE3 1 
ATOM   9024  C  CZ2 . TRP E 1 134 ? 40.615  94.874  62.336  1.00 29.86  ? 134 TRP E CZ2 1 
ATOM   9025  C  CZ3 . TRP E 1 134 ? 39.715  96.763  63.566  1.00 27.40  ? 134 TRP E CZ3 1 
ATOM   9026  C  CH2 . TRP E 1 134 ? 39.905  95.376  63.400  1.00 30.90  ? 134 TRP E CH2 1 
ATOM   9027  N  N   . PHE E 1 135 ? 43.097  98.864  63.091  1.00 29.89  ? 135 PHE E N   1 
ATOM   9028  C  CA  . PHE E 1 135 ? 42.840  98.627  64.511  1.00 22.36  ? 135 PHE E CA  1 
ATOM   9029  C  C   . PHE E 1 135 ? 43.541  99.627  65.415  1.00 28.22  ? 135 PHE E C   1 
ATOM   9030  O  O   . PHE E 1 135 ? 43.142  99.768  66.573  1.00 27.60  ? 135 PHE E O   1 
ATOM   9031  C  CB  . PHE E 1 135 ? 43.265  97.205  64.924  1.00 25.42  ? 135 PHE E CB  1 
ATOM   9032  C  CG  . PHE E 1 135 ? 44.760  97.055  65.144  1.00 24.95  ? 135 PHE E CG  1 
ATOM   9033  C  CD1 . PHE E 1 135 ? 45.610  96.811  64.078  1.00 22.66  ? 135 PHE E CD1 1 
ATOM   9034  C  CD2 . PHE E 1 135 ? 45.308  97.174  66.410  1.00 23.99  ? 135 PHE E CD2 1 
ATOM   9035  C  CE1 . PHE E 1 135 ? 46.986  96.685  64.273  1.00 24.52  ? 135 PHE E CE1 1 
ATOM   9036  C  CE2 . PHE E 1 135 ? 46.680  97.082  66.608  1.00 25.56  ? 135 PHE E CE2 1 
ATOM   9037  C  CZ  . PHE E 1 135 ? 47.523  96.814  65.542  1.00 20.87  ? 135 PHE E CZ  1 
ATOM   9038  N  N   . SER E 1 136 ? 44.603  100.285 64.950  1.00 26.13  ? 136 SER E N   1 
ATOM   9039  C  CA  . SER E 1 136 ? 45.314  101.230 65.795  1.00 27.90  ? 136 SER E CA  1 
ATOM   9040  C  C   . SER E 1 136 ? 45.194  102.674 65.333  1.00 27.93  ? 136 SER E C   1 
ATOM   9041  O  O   . SER E 1 136 ? 45.742  103.557 65.999  1.00 29.27  ? 136 SER E O   1 
ATOM   9042  C  CB  . SER E 1 136 ? 46.796  100.858 65.886  1.00 29.27  ? 136 SER E CB  1 
ATOM   9043  O  OG  . SER E 1 136 ? 47.378  100.873 64.600  1.00 29.58  ? 136 SER E OG  1 
ATOM   9044  N  N   . ALA E 1 137 ? 44.494  102.951 64.226  1.00 26.99  ? 137 ALA E N   1 
ATOM   9045  C  CA  . ALA E 1 137 ? 44.492  104.315 63.694  1.00 26.12  ? 137 ALA E CA  1 
ATOM   9046  C  C   . ALA E 1 137 ? 43.807  105.292 64.646  1.00 29.24  ? 137 ALA E C   1 
ATOM   9047  O  O   . ALA E 1 137 ? 44.224  106.453 64.762  1.00 30.98  ? 137 ALA E O   1 
ATOM   9048  C  CB  . ALA E 1 137 ? 43.814  104.356 62.329  1.00 22.48  ? 137 ALA E CB  1 
ATOM   9049  N  N   . GLY E 1 138 ? 42.756  104.845 65.335  1.00 32.69  ? 138 GLY E N   1 
ATOM   9050  C  CA  . GLY E 1 138 ? 42.046  105.741 66.232  1.00 32.97  ? 138 GLY E CA  1 
ATOM   9051  C  C   . GLY E 1 138 ? 42.936  106.258 67.343  1.00 34.78  ? 138 GLY E C   1 
ATOM   9052  O  O   . GLY E 1 138 ? 42.820  107.410 67.758  1.00 38.27  ? 138 GLY E O   1 
ATOM   9053  N  N   . GLY E 1 139 ? 43.863  105.429 67.811  1.00 32.78  ? 139 GLY E N   1 
ATOM   9054  C  CA  . GLY E 1 139 ? 44.726  105.814 68.902  1.00 27.41  ? 139 GLY E CA  1 
ATOM   9055  C  C   . GLY E 1 139 ? 45.851  106.754 68.549  1.00 27.39  ? 139 GLY E C   1 
ATOM   9056  O  O   . GLY E 1 139 ? 46.653  107.059 69.436  1.00 29.66  ? 139 GLY E O   1 
ATOM   9057  N  N   . TYR E 1 140 ? 45.939  107.222 67.301  1.00 27.11  ? 140 TYR E N   1 
ATOM   9058  C  CA  . TYR E 1 140 ? 46.964  108.171 66.862  1.00 27.43  ? 140 TYR E CA  1 
ATOM   9059  C  C   . TYR E 1 140 ? 46.292  109.466 66.422  1.00 29.49  ? 140 TYR E C   1 
ATOM   9060  O  O   . TYR E 1 140 ? 45.545  109.469 65.440  1.00 27.73  ? 140 TYR E O   1 
ATOM   9061  C  CB  . TYR E 1 140 ? 47.805  107.613 65.705  1.00 25.80  ? 140 TYR E CB  1 
ATOM   9062  C  CG  . TYR E 1 140 ? 48.819  106.573 66.136  1.00 27.40  ? 140 TYR E CG  1 
ATOM   9063  C  CD1 . TYR E 1 140 ? 49.950  106.939 66.879  1.00 26.70  ? 140 TYR E CD1 1 
ATOM   9064  C  CD2 . TYR E 1 140 ? 48.643  105.230 65.818  1.00 23.71  ? 140 TYR E CD2 1 
ATOM   9065  C  CE1 . TYR E 1 140 ? 50.879  105.986 67.309  1.00 24.68  ? 140 TYR E CE1 1 
ATOM   9066  C  CE2 . TYR E 1 140 ? 49.575  104.266 66.226  1.00 27.63  ? 140 TYR E CE2 1 
ATOM   9067  C  CZ  . TYR E 1 140 ? 50.687  104.650 66.963  1.00 26.40  ? 140 TYR E CZ  1 
ATOM   9068  O  OH  . TYR E 1 140 ? 51.593  103.700 67.370  1.00 25.14  ? 140 TYR E OH  1 
ATOM   9069  N  N   . ILE E 1 141 ? 46.604  110.567 67.109  1.00 28.56  ? 141 ILE E N   1 
ATOM   9070  C  CA  . ILE E 1 141 ? 45.967  111.861 66.873  1.00 32.75  ? 141 ILE E CA  1 
ATOM   9071  C  C   . ILE E 1 141 ? 46.917  112.712 66.045  1.00 30.88  ? 141 ILE E C   1 
ATOM   9072  O  O   . ILE E 1 141 ? 47.886  113.271 66.565  1.00 32.91  ? 141 ILE E O   1 
ATOM   9073  C  CB  . ILE E 1 141 ? 45.607  112.573 68.181  1.00 29.49  ? 141 ILE E CB  1 
ATOM   9074  C  CG1 . ILE E 1 141 ? 44.933  111.614 69.163  1.00 29.75  ? 141 ILE E CG1 1 
ATOM   9075  C  CG2 . ILE E 1 141 ? 44.726  113.773 67.889  1.00 31.30  ? 141 ILE E CG2 1 
ATOM   9076  C  CD1 . ILE E 1 141 ? 43.606  111.052 68.675  1.00 32.56  ? 141 ILE E CD1 1 
ATOM   9077  N  N   . ARG E 1 142 ? 46.610  112.859 64.758  1.00 29.86  ? 142 ARG E N   1 
ATOM   9078  C  CA  . ARG E 1 142 ? 47.498  113.597 63.862  1.00 37.11  ? 142 ARG E CA  1 
ATOM   9079  C  C   . ARG E 1 142 ? 47.618  115.069 64.250  1.00 37.88  ? 142 ARG E C   1 
ATOM   9080  O  O   . ARG E 1 142 ? 48.646  115.693 63.974  1.00 34.69  ? 142 ARG E O   1 
ATOM   9081  C  CB  . ARG E 1 142 ? 47.017  113.467 62.416  1.00 39.42  ? 142 ARG E CB  1 
ATOM   9082  C  CG  . ARG E 1 142 ? 47.477  112.201 61.714  1.00 44.74  ? 142 ARG E CG  1 
ATOM   9083  C  CD  . ARG E 1 142 ? 47.438  112.344 60.178  1.00 52.57  ? 142 ARG E CD  1 
ATOM   9084  N  NE  . ARG E 1 142 ? 48.688  111.881 59.585  1.00 57.94  ? 142 ARG E NE  1 
ATOM   9085  C  CZ  . ARG E 1 142 ? 48.814  111.349 58.375  1.00 69.60  ? 142 ARG E CZ  1 
ATOM   9086  N  NH1 . ARG E 1 142 ? 47.766  111.169 57.584  1.00 72.49  ? 142 ARG E NH1 1 
ATOM   9087  N  NH2 . ARG E 1 142 ? 50.024  110.987 57.948  1.00 65.99  ? 142 ARG E NH2 1 
ATOM   9088  N  N   . ALA E 1 143 ? 46.583  115.643 64.872  1.00 30.72  ? 143 ALA E N   1 
ATOM   9089  C  CA  . ALA E 1 143 ? 46.656  117.040 65.287  1.00 36.59  ? 143 ALA E CA  1 
ATOM   9090  C  C   . ALA E 1 143 ? 47.753  117.255 66.322  1.00 39.30  ? 143 ALA E C   1 
ATOM   9091  O  O   . ALA E 1 143 ? 48.344  118.339 66.387  1.00 42.08  ? 143 ALA E O   1 
ATOM   9092  C  CB  . ALA E 1 143 ? 45.303  117.502 65.846  1.00 38.17  ? 143 ALA E CB  1 
ATOM   9093  N  N   . ASP E 1 144 ? 48.030  116.239 67.137  1.00 35.52  ? 144 ASP E N   1 
ATOM   9094  C  CA  . ASP E 1 144 ? 49.116  116.322 68.106  1.00 36.26  ? 144 ASP E CA  1 
ATOM   9095  C  C   . ASP E 1 144 ? 50.489  116.246 67.426  1.00 35.06  ? 144 ASP E C   1 
ATOM   9096  O  O   . ASP E 1 144 ? 51.282  117.189 67.511  1.00 36.05  ? 144 ASP E O   1 
ATOM   9097  C  CB  . ASP E 1 144 ? 48.955  115.220 69.159  1.00 34.04  ? 144 ASP E CB  1 
ATOM   9098  C  CG  . ASP E 1 144 ? 47.955  115.589 70.256  1.00 36.71  ? 144 ASP E CG  1 
ATOM   9099  O  OD1 . ASP E 1 144 ? 47.508  116.761 70.313  1.00 42.74  ? 144 ASP E OD1 1 
ATOM   9100  O  OD2 . ASP E 1 144 ? 47.627  114.714 71.077  1.00 33.76  ? 144 ASP E OD2 1 
ATOM   9101  N  N   . PHE E 1 145 ? 50.792  115.142 66.727  1.00 35.88  ? 145 PHE E N   1 
ATOM   9102  C  CA  . PHE E 1 145 ? 52.175  114.902 66.293  1.00 33.57  ? 145 PHE E CA  1 
ATOM   9103  C  C   . PHE E 1 145 ? 52.475  115.312 64.855  1.00 34.13  ? 145 PHE E C   1 
ATOM   9104  O  O   . PHE E 1 145 ? 53.654  115.375 64.477  1.00 36.64  ? 145 PHE E O   1 
ATOM   9105  C  CB  . PHE E 1 145 ? 52.557  113.428 66.479  1.00 29.35  ? 145 PHE E CB  1 
ATOM   9106  C  CG  . PHE E 1 145 ? 51.716  112.478 65.692  1.00 33.57  ? 145 PHE E CG  1 
ATOM   9107  C  CD1 . PHE E 1 145 ? 52.043  112.164 64.374  1.00 30.41  ? 145 PHE E CD1 1 
ATOM   9108  C  CD2 . PHE E 1 145 ? 50.601  111.884 66.268  1.00 30.71  ? 145 PHE E CD2 1 
ATOM   9109  C  CE1 . PHE E 1 145 ? 51.267  111.289 63.637  1.00 31.73  ? 145 PHE E CE1 1 
ATOM   9110  C  CE2 . PHE E 1 145 ? 49.814  110.996 65.540  1.00 27.74  ? 145 PHE E CE2 1 
ATOM   9111  C  CZ  . PHE E 1 145 ? 50.140  110.698 64.227  1.00 31.84  ? 145 PHE E CZ  1 
ATOM   9112  N  N   . ASP E 1 146 ? 51.469  115.588 64.034  1.00 33.76  ? 146 ASP E N   1 
ATOM   9113  C  CA  . ASP E 1 146 ? 51.716  115.903 62.627  1.00 38.15  ? 146 ASP E CA  1 
ATOM   9114  C  C   . ASP E 1 146 ? 51.721  117.425 62.488  1.00 38.64  ? 146 ASP E C   1 
ATOM   9115  O  O   . ASP E 1 146 ? 50.756  118.050 62.059  1.00 38.38  ? 146 ASP E O   1 
ATOM   9116  C  CB  . ASP E 1 146 ? 50.676  115.220 61.732  1.00 41.17  ? 146 ASP E CB  1 
ATOM   9117  C  CG  . ASP E 1 146 ? 51.037  115.251 60.251  1.00 43.18  ? 146 ASP E CG  1 
ATOM   9118  O  OD1 . ASP E 1 146 ? 52.182  115.613 59.911  1.00 38.81  ? 146 ASP E OD1 1 
ATOM   9119  O  OD2 . ASP E 1 146 ? 50.164  114.894 59.427  1.00 45.99  ? 146 ASP E OD2 1 
ATOM   9120  N  N   . ARG E 1 147 ? 52.846  118.024 62.872  1.00 43.83  ? 147 ARG E N   1 
ATOM   9121  C  CA  . ARG E 1 147 ? 53.017  119.475 62.834  1.00 45.91  ? 147 ARG E CA  1 
ATOM   9122  C  C   . ARG E 1 147 ? 54.308  119.800 62.097  1.00 45.40  ? 147 ARG E C   1 
ATOM   9123  O  O   . ARG E 1 147 ? 55.396  119.372 62.536  1.00 47.97  ? 147 ARG E O   1 
ATOM   9124  C  CB  . ARG E 1 147 ? 53.033  120.062 64.245  1.00 42.43  ? 147 ARG E CB  1 
ATOM   9125  C  CG  . ARG E 1 147 ? 51.765  119.827 65.024  1.00 38.43  ? 147 ARG E CG  1 
ATOM   9126  C  CD  . ARG E 1 147 ? 51.946  120.218 66.479  1.00 38.25  ? 147 ARG E CD  1 
ATOM   9127  N  NE  . ARG E 1 147 ? 50.727  119.983 67.246  1.00 41.50  ? 147 ARG E NE  1 
ATOM   9128  C  CZ  . ARG E 1 147 ? 50.186  120.864 68.076  1.00 44.47  ? 147 ARG E CZ  1 
ATOM   9129  N  NH1 . ARG E 1 147 ? 50.756  122.040 68.300  1.00 45.11  ? 147 ARG E NH1 1 
ATOM   9130  N  NH2 . ARG E 1 147 ? 49.048  120.559 68.697  1.00 36.97  ? 147 ARG E NH2 1 
ATOM   9131  N  N   . PRO E 1 148 ? 54.251  120.554 60.999  1.00 52.59  ? 148 PRO E N   1 
ATOM   9132  C  CA  . PRO E 1 148 ? 55.454  120.761 60.171  1.00 51.94  ? 148 PRO E CA  1 
ATOM   9133  C  C   . PRO E 1 148 ? 56.605  121.450 60.894  1.00 51.56  ? 148 PRO E C   1 
ATOM   9134  O  O   . PRO E 1 148 ? 57.764  121.257 60.509  1.00 54.77  ? 148 PRO E O   1 
ATOM   9135  C  CB  . PRO E 1 148 ? 54.929  121.626 59.016  1.00 59.34  ? 148 PRO E CB  1 
ATOM   9136  C  CG  . PRO E 1 148 ? 53.429  121.367 59.002  1.00 61.80  ? 148 PRO E CG  1 
ATOM   9137  C  CD  . PRO E 1 148 ? 53.071  121.238 60.448  1.00 53.89  ? 148 PRO E CD  1 
ATOM   9138  N  N   . ASP E 1 149 ? 56.322  122.226 61.936  1.00 46.31  ? 149 ASP E N   1 
ATOM   9139  C  CA  . ASP E 1 149 ? 57.301  123.052 62.629  1.00 47.53  ? 149 ASP E CA  1 
ATOM   9140  C  C   . ASP E 1 149 ? 58.192  122.279 63.599  1.00 47.53  ? 149 ASP E C   1 
ATOM   9141  O  O   . ASP E 1 149 ? 59.182  122.838 64.080  1.00 47.07  ? 149 ASP E O   1 
ATOM   9142  C  CB  . ASP E 1 149 ? 56.549  124.128 63.398  1.00 48.17  ? 149 ASP E CB  1 
ATOM   9143  C  CG  . ASP E 1 149 ? 55.352  123.553 64.153  1.00 53.25  ? 149 ASP E CG  1 
ATOM   9144  O  OD1 . ASP E 1 149 ? 54.469  122.934 63.502  1.00 49.29  ? 149 ASP E OD1 1 
ATOM   9145  O  OD2 . ASP E 1 149 ? 55.305  123.706 65.395  1.00 49.74  ? 149 ASP E OD2 1 
ATOM   9146  N  N   . VAL E 1 150 ? 57.864  121.028 63.907  1.00 45.20  ? 150 VAL E N   1 
ATOM   9147  C  CA  . VAL E 1 150 ? 58.532  120.273 64.964  1.00 38.40  ? 150 VAL E CA  1 
ATOM   9148  C  C   . VAL E 1 150 ? 59.909  119.794 64.504  1.00 37.43  ? 150 VAL E C   1 
ATOM   9149  O  O   . VAL E 1 150 ? 60.070  119.298 63.382  1.00 37.13  ? 150 VAL E O   1 
ATOM   9150  C  CB  . VAL E 1 150 ? 57.632  119.101 65.385  1.00 40.20  ? 150 VAL E CB  1 
ATOM   9151  C  CG1 . VAL E 1 150 ? 58.248  118.286 66.530  1.00 36.33  ? 150 VAL E CG1 1 
ATOM   9152  C  CG2 . VAL E 1 150 ? 56.256  119.636 65.756  1.00 40.92  ? 150 VAL E CG2 1 
ATOM   9153  N  N   . LYS E 1 151 ? 60.913  119.947 65.374  1.00 33.93  ? 151 LYS E N   1 
ATOM   9154  C  CA  . LYS E 1 151 ? 62.240  119.366 65.175  1.00 33.30  ? 151 LYS E CA  1 
ATOM   9155  C  C   . LYS E 1 151 ? 62.277  117.968 65.779  1.00 32.65  ? 151 LYS E C   1 
ATOM   9156  O  O   . LYS E 1 151 ? 62.204  117.824 67.004  1.00 33.22  ? 151 LYS E O   1 
ATOM   9157  C  CB  . LYS E 1 151 ? 63.333  120.197 65.846  1.00 32.93  ? 151 LYS E CB  1 
ATOM   9158  C  CG  . LYS E 1 151 ? 63.450  121.630 65.404  1.00 44.62  ? 151 LYS E CG  1 
ATOM   9159  C  CD  . LYS E 1 151 ? 64.623  122.301 66.129  1.00 51.35  ? 151 LYS E CD  1 
ATOM   9160  C  CE  . LYS E 1 151 ? 65.925  122.139 65.350  1.00 44.99  ? 151 LYS E CE  1 
ATOM   9161  N  NZ  . LYS E 1 151 ? 66.022  123.172 64.279  1.00 56.92  ? 151 LYS E NZ  1 
ATOM   9162  N  N   . TRP E 1 152 ? 62.430  116.951 64.939  1.00 29.91  ? 152 TRP E N   1 
ATOM   9163  C  CA  . TRP E 1 152 ? 62.480  115.568 65.399  1.00 28.82  ? 152 TRP E CA  1 
ATOM   9164  C  C   . TRP E 1 152 ? 63.898  115.036 65.282  1.00 26.38  ? 152 TRP E C   1 
ATOM   9165  O  O   . TRP E 1 152 ? 64.592  115.312 64.301  1.00 32.86  ? 152 TRP E O   1 
ATOM   9166  C  CB  . TRP E 1 152 ? 61.567  114.654 64.584  1.00 26.34  ? 152 TRP E CB  1 
ATOM   9167  C  CG  . TRP E 1 152 ? 60.093  114.912 64.673  1.00 24.96  ? 152 TRP E CG  1 
ATOM   9168  C  CD1 . TRP E 1 152 ? 59.355  115.644 63.798  1.00 25.18  ? 152 TRP E CD1 1 
ATOM   9169  C  CD2 . TRP E 1 152 ? 59.161  114.372 65.629  1.00 25.86  ? 152 TRP E CD2 1 
ATOM   9170  N  NE1 . TRP E 1 152 ? 58.033  115.623 64.155  1.00 29.61  ? 152 TRP E NE1 1 
ATOM   9171  C  CE2 . TRP E 1 152 ? 57.883  114.856 65.280  1.00 29.16  ? 152 TRP E CE2 1 
ATOM   9172  C  CE3 . TRP E 1 152 ? 59.283  113.549 66.750  1.00 25.88  ? 152 TRP E CE3 1 
ATOM   9173  C  CZ2 . TRP E 1 152 ? 56.721  114.542 66.020  1.00 26.78  ? 152 TRP E CZ2 1 
ATOM   9174  C  CZ3 . TRP E 1 152 ? 58.128  113.237 67.486  1.00 29.30  ? 152 TRP E CZ3 1 
ATOM   9175  C  CH2 . TRP E 1 152 ? 56.865  113.736 67.110  1.00 28.05  ? 152 TRP E CH2 1 
ATOM   9176  N  N   . HIS E 1 153 ? 64.327  114.292 66.293  1.00 26.12  ? 153 HIS E N   1 
ATOM   9177  C  CA  . HIS E 1 153 ? 65.426  113.342 66.175  1.00 27.69  ? 153 HIS E CA  1 
ATOM   9178  C  C   . HIS E 1 153 ? 64.796  111.950 66.173  1.00 26.71  ? 153 HIS E C   1 
ATOM   9179  O  O   . HIS E 1 153 ? 64.189  111.529 67.172  1.00 24.96  ? 153 HIS E O   1 
ATOM   9180  C  CB  . HIS E 1 153 ? 66.442  113.507 67.304  1.00 25.89  ? 153 HIS E CB  1 
ATOM   9181  C  CG  . HIS E 1 153 ? 67.598  112.553 67.221  1.00 28.61  ? 153 HIS E CG  1 
ATOM   9182  N  ND1 . HIS E 1 153 ? 68.064  112.048 66.023  1.00 28.66  ? 153 HIS E ND1 1 
ATOM   9183  C  CD2 . HIS E 1 153 ? 68.387  112.019 68.185  1.00 26.85  ? 153 HIS E CD2 1 
ATOM   9184  C  CE1 . HIS E 1 153 ? 69.089  111.247 66.251  1.00 25.88  ? 153 HIS E CE1 1 
ATOM   9185  N  NE2 . HIS E 1 153 ? 69.309  111.215 67.554  1.00 28.79  ? 153 HIS E NE2 1 
ATOM   9186  N  N   . LEU E 1 154 ? 64.882  111.260 65.037  1.00 22.17  ? 154 LEU E N   1 
ATOM   9187  C  CA  . LEU E 1 154 ? 64.229  109.965 64.872  1.00 22.72  ? 154 LEU E CA  1 
ATOM   9188  C  C   . LEU E 1 154 ? 65.285  108.888 65.076  1.00 20.98  ? 154 LEU E C   1 
ATOM   9189  O  O   . LEU E 1 154 ? 66.181  108.710 64.245  1.00 25.77  ? 154 LEU E O   1 
ATOM   9190  C  CB  . LEU E 1 154 ? 63.537  109.850 63.515  1.00 22.75  ? 154 LEU E CB  1 
ATOM   9191  C  CG  . LEU E 1 154 ? 62.428  110.903 63.297  1.00 29.29  ? 154 LEU E CG  1 
ATOM   9192  C  CD1 . LEU E 1 154 ? 61.734  110.806 61.900  1.00 26.79  ? 154 LEU E CD1 1 
ATOM   9193  C  CD2 . LEU E 1 154 ? 61.397  110.839 64.398  1.00 21.78  ? 154 LEU E CD2 1 
ATOM   9194  N  N   . LEU E 1 155 ? 65.180  108.186 66.189  1.00 20.61  ? 155 LEU E N   1 
ATOM   9195  C  CA  . LEU E 1 155 ? 66.153  107.176 66.549  1.00 22.86  ? 155 LEU E CA  1 
ATOM   9196  C  C   . LEU E 1 155 ? 66.041  105.981 65.602  1.00 27.38  ? 155 LEU E C   1 
ATOM   9197  O  O   . LEU E 1 155 ? 64.950  105.638 65.127  1.00 26.59  ? 155 LEU E O   1 
ATOM   9198  C  CB  . LEU E 1 155 ? 65.925  106.740 67.996  1.00 23.51  ? 155 LEU E CB  1 
ATOM   9199  C  CG  . LEU E 1 155 ? 66.029  107.822 69.087  1.00 22.25  ? 155 LEU E CG  1 
ATOM   9200  C  CD1 . LEU E 1 155 ? 65.783  107.228 70.490  1.00 21.49  ? 155 LEU E CD1 1 
ATOM   9201  C  CD2 . LEU E 1 155 ? 67.393  108.506 69.043  1.00 20.86  ? 155 LEU E CD2 1 
ATOM   9202  N  N   . GLU E 1 156 ? 67.182  105.349 65.329  1.00 23.05  ? 156 GLU E N   1 
ATOM   9203  C  CA  . GLU E 1 156 ? 67.234  104.125 64.543  1.00 31.04  ? 156 GLU E CA  1 
ATOM   9204  C  C   . GLU E 1 156 ? 67.363  102.910 65.465  1.00 31.10  ? 156 GLU E C   1 
ATOM   9205  O  O   . GLU E 1 156 ? 67.453  103.028 66.690  1.00 28.27  ? 156 GLU E O   1 
ATOM   9206  C  CB  . GLU E 1 156 ? 68.383  104.180 63.533  1.00 27.58  ? 156 GLU E CB  1 
ATOM   9207  C  CG  . GLU E 1 156 ? 68.362  105.410 62.633  1.00 31.36  ? 156 GLU E CG  1 
ATOM   9208  C  CD  . GLU E 1 156 ? 67.360  105.277 61.502  1.00 32.56  ? 156 GLU E CD  1 
ATOM   9209  O  OE1 . GLU E 1 156 ? 66.809  104.173 61.349  1.00 37.98  ? 156 GLU E OE1 1 
ATOM   9210  O  OE2 . GLU E 1 156 ? 67.125  106.257 60.767  1.00 32.81  ? 156 GLU E OE2 1 
ATOM   9211  N  N   . GLY E 1 157 ? 67.381  101.723 64.852  1.00 34.50  ? 157 GLY E N   1 
ATOM   9212  C  CA  . GLY E 1 157 ? 67.367  100.489 65.628  1.00 32.39  ? 157 GLY E CA  1 
ATOM   9213  C  C   . GLY E 1 157 ? 68.602  100.316 66.488  1.00 36.70  ? 157 GLY E C   1 
ATOM   9214  O  O   . GLY E 1 157 ? 68.525  99.788  67.603  1.00 42.28  ? 157 GLY E O   1 
ATOM   9215  N  N   . HIS E 1 158 ? 69.757  100.763 65.988  1.00 37.23  ? 158 HIS E N   1 
ATOM   9216  C  CA  . HIS E 1 158 ? 71.016  100.683 66.721  1.00 40.65  ? 158 HIS E CA  1 
ATOM   9217  C  C   . HIS E 1 158 ? 71.098  101.685 67.858  1.00 36.39  ? 158 HIS E C   1 
ATOM   9218  O  O   . HIS E 1 158 ? 72.110  101.705 68.560  1.00 37.03  ? 158 HIS E O   1 
ATOM   9219  C  CB  . HIS E 1 158 ? 72.197  100.901 65.767  1.00 43.45  ? 158 HIS E CB  1 
ATOM   9220  C  CG  . HIS E 1 158 ? 72.409  99.780  64.792  1.00 58.19  ? 158 HIS E CG  1 
ATOM   9221  N  ND1 . HIS E 1 158 ? 72.541  98.462  65.181  1.00 64.00  ? 158 HIS E ND1 1 
ATOM   9222  C  CD2 . HIS E 1 158 ? 72.480  99.780  63.438  1.00 56.51  ? 158 HIS E CD2 1 
ATOM   9223  C  CE1 . HIS E 1 158 ? 72.698  97.703  64.109  1.00 55.93  ? 158 HIS E CE1 1 
ATOM   9224  N  NE2 . HIS E 1 158 ? 72.662  98.478  63.040  1.00 54.08  ? 158 HIS E NE2 1 
ATOM   9225  N  N   . ASP E 1 159 ? 70.080  102.515 68.053  1.00 31.89  ? 159 ASP E N   1 
ATOM   9226  C  CA  . ASP E 1 159 ? 70.127  103.588 69.033  1.00 30.80  ? 159 ASP E CA  1 
ATOM   9227  C  C   . ASP E 1 159 ? 69.567  103.177 70.395  1.00 27.96  ? 159 ASP E C   1 
ATOM   9228  O  O   . ASP E 1 159 ? 69.366  104.043 71.253  1.00 28.52  ? 159 ASP E O   1 
ATOM   9229  C  CB  . ASP E 1 159 ? 69.368  104.807 68.504  1.00 26.87  ? 159 ASP E CB  1 
ATOM   9230  C  CG  . ASP E 1 159 ? 70.139  105.554 67.466  1.00 28.91  ? 159 ASP E CG  1 
ATOM   9231  O  OD1 . ASP E 1 159 ? 71.369  105.665 67.639  1.00 38.19  ? 159 ASP E OD1 1 
ATOM   9232  O  OD2 . ASP E 1 159 ? 69.537  106.027 66.475  1.00 28.52  ? 159 ASP E OD2 1 
ATOM   9233  N  N   . ASP E 1 160 ? 69.300  101.889 70.607  1.00 25.40  ? 160 ASP E N   1 
ATOM   9234  C  CA  . ASP E 1 160 ? 68.826  101.439 71.909  1.00 25.36  ? 160 ASP E CA  1 
ATOM   9235  C  C   . ASP E 1 160 ? 69.813  101.895 72.976  1.00 27.34  ? 160 ASP E C   1 
ATOM   9236  O  O   . ASP E 1 160 ? 71.028  101.853 72.773  1.00 24.31  ? 160 ASP E O   1 
ATOM   9237  C  CB  . ASP E 1 160 ? 68.659  99.913  71.921  1.00 24.71  ? 160 ASP E CB  1 
ATOM   9238  C  CG  . ASP E 1 160 ? 67.875  99.400  73.154  1.00 31.51  ? 160 ASP E CG  1 
ATOM   9239  O  OD1 . ASP E 1 160 ? 67.170  100.193 73.820  1.00 27.23  ? 160 ASP E OD1 1 
ATOM   9240  O  OD2 . ASP E 1 160 ? 67.964  98.187  73.458  1.00 31.12  ? 160 ASP E OD2 1 
ATOM   9241  N  N   . GLY E 1 161 ? 69.289  102.397 74.092  1.00 24.00  ? 161 GLY E N   1 
ATOM   9242  C  CA  . GLY E 1 161 ? 70.139  102.962 75.121  1.00 22.88  ? 161 GLY E CA  1 
ATOM   9243  C  C   . GLY E 1 161 ? 70.489  104.427 74.932  1.00 27.67  ? 161 GLY E C   1 
ATOM   9244  O  O   . GLY E 1 161 ? 71.309  104.950 75.696  1.00 27.31  ? 161 GLY E O   1 
ATOM   9245  N  N   . TYR E 1 162 ? 69.902  105.099 73.938  1.00 22.84  ? 162 TYR E N   1 
ATOM   9246  C  CA  . TYR E 1 162 ? 70.268  106.478 73.623  1.00 25.89  ? 162 TYR E CA  1 
ATOM   9247  C  C   . TYR E 1 162 ? 70.248  107.361 74.876  1.00 27.65  ? 162 TYR E C   1 
ATOM   9248  O  O   . TYR E 1 162 ? 69.275  107.373 75.640  1.00 23.75  ? 162 TYR E O   1 
ATOM   9249  C  CB  . TYR E 1 162 ? 69.320  107.032 72.551  1.00 22.22  ? 162 TYR E CB  1 
ATOM   9250  C  CG  . TYR E 1 162 ? 69.726  108.405 72.076  1.00 21.63  ? 162 TYR E CG  1 
ATOM   9251  C  CD1 . TYR E 1 162 ? 70.758  108.562 71.151  1.00 24.11  ? 162 TYR E CD1 1 
ATOM   9252  C  CD2 . TYR E 1 162 ? 69.106  109.555 72.576  1.00 21.68  ? 162 TYR E CD2 1 
ATOM   9253  C  CE1 . TYR E 1 162 ? 71.163  109.826 70.718  1.00 23.44  ? 162 TYR E CE1 1 
ATOM   9254  C  CE2 . TYR E 1 162 ? 69.504  110.831 72.151  1.00 23.05  ? 162 TYR E CE2 1 
ATOM   9255  C  CZ  . TYR E 1 162 ? 70.529  110.956 71.223  1.00 27.33  ? 162 TYR E CZ  1 
ATOM   9256  O  OH  . TYR E 1 162 ? 70.934  112.202 70.804  1.00 26.83  ? 162 TYR E OH  1 
ATOM   9257  N  N   . ASP E 1 163 ? 71.339  108.082 75.090  1.00 26.37  ? 163 ASP E N   1 
ATOM   9258  C  CA  . ASP E 1 163 ? 71.578  108.855 76.307  1.00 25.77  ? 163 ASP E CA  1 
ATOM   9259  C  C   . ASP E 1 163 ? 71.370  110.324 75.967  1.00 29.41  ? 163 ASP E C   1 
ATOM   9260  O  O   . ASP E 1 163 ? 72.147  110.906 75.196  1.00 25.34  ? 163 ASP E O   1 
ATOM   9261  C  CB  . ASP E 1 163 ? 72.988  108.581 76.825  1.00 30.94  ? 163 ASP E CB  1 
ATOM   9262  C  CG  . ASP E 1 163 ? 73.290  109.272 78.149  1.00 33.13  ? 163 ASP E CG  1 
ATOM   9263  O  OD1 . ASP E 1 163 ? 72.646  110.299 78.475  1.00 32.04  ? 163 ASP E OD1 1 
ATOM   9264  O  OD2 . ASP E 1 163 ? 74.195  108.773 78.859  1.00 34.33  ? 163 ASP E OD2 1 
ATOM   9265  N  N   . VAL E 1 164 ? 70.317  110.922 76.537  1.00 28.27  ? 164 VAL E N   1 
ATOM   9266  C  CA  . VAL E 1 164 ? 69.859  112.222 76.047  1.00 25.10  ? 164 VAL E CA  1 
ATOM   9267  C  C   . VAL E 1 164 ? 70.931  113.286 76.275  1.00 28.01  ? 164 VAL E C   1 
ATOM   9268  O  O   . VAL E 1 164 ? 71.239  114.088 75.384  1.00 25.30  ? 164 VAL E O   1 
ATOM   9269  C  CB  . VAL E 1 164 ? 68.522  112.616 76.706  1.00 24.71  ? 164 VAL E CB  1 
ATOM   9270  C  CG1 . VAL E 1 164 ? 68.049  113.966 76.152  1.00 28.81  ? 164 VAL E CG1 1 
ATOM   9271  C  CG2 . VAL E 1 164 ? 67.460  111.559 76.467  1.00 23.61  ? 164 VAL E CG2 1 
ATOM   9272  N  N   . PHE E 1 165 ? 71.523  113.302 77.468  1.00 25.51  ? 165 PHE E N   1 
ATOM   9273  C  CA  . PHE E 1 165 ? 72.504  114.318 77.808  1.00 35.57  ? 165 PHE E CA  1 
ATOM   9274  C  C   . PHE E 1 165 ? 73.938  113.814 77.704  1.00 36.84  ? 165 PHE E C   1 
ATOM   9275  O  O   . PHE E 1 165 ? 74.871  114.619 77.792  1.00 40.27  ? 165 PHE E O   1 
ATOM   9276  C  CB  . PHE E 1 165 ? 72.242  114.840 79.232  1.00 34.11  ? 165 PHE E CB  1 
ATOM   9277  C  CG  . PHE E 1 165 ? 71.043  115.727 79.345  1.00 30.27  ? 165 PHE E CG  1 
ATOM   9278  C  CD1 . PHE E 1 165 ? 71.013  116.966 78.710  1.00 32.14  ? 165 PHE E CD1 1 
ATOM   9279  C  CD2 . PHE E 1 165 ? 69.946  115.332 80.083  1.00 30.16  ? 165 PHE E CD2 1 
ATOM   9280  C  CE1 . PHE E 1 165 ? 69.905  117.795 78.819  1.00 32.44  ? 165 PHE E CE1 1 
ATOM   9281  C  CE2 . PHE E 1 165 ? 68.838  116.155 80.193  1.00 33.19  ? 165 PHE E CE2 1 
ATOM   9282  C  CZ  . PHE E 1 165 ? 68.822  117.390 79.565  1.00 28.27  ? 165 PHE E CZ  1 
ATOM   9283  N  N   . GLY E 1 166 ? 74.137  112.514 77.523  1.00 32.87  ? 166 GLY E N   1 
ATOM   9284  C  CA  . GLY E 1 166 ? 75.475  111.951 77.564  1.00 34.57  ? 166 GLY E CA  1 
ATOM   9285  C  C   . GLY E 1 166 ? 76.030  111.772 78.958  1.00 33.77  ? 166 GLY E C   1 
ATOM   9286  O  O   . GLY E 1 166 ? 77.246  111.695 79.122  1.00 32.41  ? 166 GLY E O   1 
ATOM   9287  N  N   . ASP E 1 167 ? 75.165  111.687 79.974  1.00 33.63  ? 167 ASP E N   1 
ATOM   9288  C  CA  . ASP E 1 167 ? 75.605  111.684 81.363  1.00 36.40  ? 167 ASP E CA  1 
ATOM   9289  C  C   . ASP E 1 167 ? 74.865  110.647 82.196  1.00 32.93  ? 167 ASP E C   1 
ATOM   9290  O  O   . ASP E 1 167 ? 74.914  110.722 83.429  1.00 29.15  ? 167 ASP E O   1 
ATOM   9291  C  CB  . ASP E 1 167 ? 75.411  113.070 82.014  1.00 30.88  ? 167 ASP E CB  1 
ATOM   9292  C  CG  . ASP E 1 167 ? 73.930  113.470 82.128  1.00 35.92  ? 167 ASP E CG  1 
ATOM   9293  O  OD1 . ASP E 1 167 ? 73.043  112.732 81.625  1.00 32.32  ? 167 ASP E OD1 1 
ATOM   9294  O  OD2 . ASP E 1 167 ? 73.645  114.520 82.753  1.00 38.17  ? 167 ASP E OD2 1 
ATOM   9295  N  N   . ASP E 1 168 ? 74.160  109.711 81.551  1.00 28.84  ? 168 ASP E N   1 
ATOM   9296  C  CA  . ASP E 1 168 ? 73.424  108.614 82.176  1.00 31.57  ? 168 ASP E CA  1 
ATOM   9297  C  C   . ASP E 1 168 ? 72.183  109.048 82.934  1.00 29.75  ? 168 ASP E C   1 
ATOM   9298  O  O   . ASP E 1 168 ? 71.562  108.213 83.602  1.00 33.21  ? 168 ASP E O   1 
ATOM   9299  C  CB  . ASP E 1 168 ? 74.299  107.797 83.130  1.00 34.03  ? 168 ASP E CB  1 
ATOM   9300  C  CG  . ASP E 1 168 ? 74.912  106.624 82.448  1.00 40.94  ? 168 ASP E CG  1 
ATOM   9301  O  OD1 . ASP E 1 168 ? 74.148  105.727 82.017  1.00 38.44  ? 168 ASP E OD1 1 
ATOM   9302  O  OD2 . ASP E 1 168 ? 76.153  106.629 82.290  1.00 48.50  ? 168 ASP E OD2 1 
ATOM   9303  N  N   . THR E 1 169 ? 71.793  110.317 82.855  1.00 28.44  ? 169 THR E N   1 
ATOM   9304  C  CA  . THR E 1 169 ? 70.578  110.749 83.542  1.00 31.56  ? 169 THR E CA  1 
ATOM   9305  C  C   . THR E 1 169 ? 69.331  110.134 82.914  1.00 29.86  ? 169 THR E C   1 
ATOM   9306  O  O   . THR E 1 169 ? 68.435  109.674 83.629  1.00 29.82  ? 169 THR E O   1 
ATOM   9307  C  CB  . THR E 1 169 ? 70.483  112.277 83.532  1.00 32.00  ? 169 THR E CB  1 
ATOM   9308  O  OG1 . THR E 1 169 ? 71.746  112.822 83.914  1.00 34.89  ? 169 THR E OG1 1 
ATOM   9309  C  CG2 . THR E 1 169 ? 69.402  112.756 84.526  1.00 36.33  ? 169 THR E CG2 1 
ATOM   9310  N  N   . ILE E 1 170 ? 69.242  110.140 81.573  1.00 28.69  ? 170 ILE E N   1 
ATOM   9311  C  CA  . ILE E 1 170 ? 68.063  109.658 80.847  1.00 27.45  ? 170 ILE E CA  1 
ATOM   9312  C  C   . ILE E 1 170 ? 68.520  108.814 79.668  1.00 25.98  ? 170 ILE E C   1 
ATOM   9313  O  O   . ILE E 1 170 ? 69.243  109.307 78.794  1.00 26.81  ? 170 ILE E O   1 
ATOM   9314  C  CB  . ILE E 1 170 ? 67.160  110.793 80.320  1.00 26.87  ? 170 ILE E CB  1 
ATOM   9315  C  CG1 . ILE E 1 170 ? 66.983  111.915 81.338  1.00 27.39  ? 170 ILE E CG1 1 
ATOM   9316  C  CG2 . ILE E 1 170 ? 65.811  110.235 79.897  1.00 28.13  ? 170 ILE E CG2 1 
ATOM   9317  C  CD1 . ILE E 1 170 ? 66.462  113.215 80.716  1.00 31.73  ? 170 ILE E CD1 1 
ATOM   9318  N  N   . ARG E 1 171 ? 68.061  107.560 79.611  1.00 26.42  ? 171 ARG E N   1 
ATOM   9319  C  CA  . ARG E 1 171 ? 68.305  106.688 78.467  1.00 27.40  ? 171 ARG E CA  1 
ATOM   9320  C  C   . ARG E 1 171 ? 67.016  106.051 77.971  1.00 23.28  ? 171 ARG E C   1 
ATOM   9321  O  O   . ARG E 1 171 ? 66.198  105.568 78.768  1.00 23.32  ? 171 ARG E O   1 
ATOM   9322  C  CB  . ARG E 1 171 ? 69.284  105.556 78.795  1.00 26.85  ? 171 ARG E CB  1 
ATOM   9323  C  CG  . ARG E 1 171 ? 70.716  105.952 79.017  1.00 29.32  ? 171 ARG E CG  1 
ATOM   9324  C  CD  . ARG E 1 171 ? 71.528  104.678 79.290  1.00 30.55  ? 171 ARG E CD  1 
ATOM   9325  N  NE  . ARG E 1 171 ? 72.936  104.963 79.504  1.00 37.38  ? 171 ARG E NE  1 
ATOM   9326  C  CZ  . ARG E 1 171 ? 73.874  104.871 78.572  1.00 42.05  ? 171 ARG E CZ  1 
ATOM   9327  N  NH1 . ARG E 1 171 ? 73.590  104.469 77.339  1.00 34.36  ? 171 ARG E NH1 1 
ATOM   9328  N  NH2 . ARG E 1 171 ? 75.128  105.205 78.879  1.00 40.40  ? 171 ARG E NH2 1 
ATOM   9329  N  N   . PHE E 1 172 ? 66.870  106.020 76.647  1.00 20.04  ? 172 PHE E N   1 
ATOM   9330  C  CA  . PHE E 1 172 ? 65.824  105.228 76.014  1.00 22.81  ? 172 PHE E CA  1 
ATOM   9331  C  C   . PHE E 1 172 ? 66.113  103.744 76.177  1.00 24.14  ? 172 PHE E C   1 
ATOM   9332  O  O   . PHE E 1 172 ? 67.213  103.280 75.850  1.00 27.69  ? 172 PHE E O   1 
ATOM   9333  C  CB  . PHE E 1 172 ? 65.736  105.535 74.520  1.00 21.82  ? 172 PHE E CB  1 
ATOM   9334  C  CG  . PHE E 1 172 ? 65.093  106.833 74.189  1.00 21.11  ? 172 PHE E CG  1 
ATOM   9335  C  CD1 . PHE E 1 172 ? 65.756  108.031 74.410  1.00 22.06  ? 172 PHE E CD1 1 
ATOM   9336  C  CD2 . PHE E 1 172 ? 63.844  106.858 73.599  1.00 22.84  ? 172 PHE E CD2 1 
ATOM   9337  C  CE1 . PHE E 1 172 ? 65.181  109.229 74.054  1.00 21.20  ? 172 PHE E CE1 1 
ATOM   9338  C  CE2 . PHE E 1 172 ? 63.264  108.045 73.239  1.00 21.01  ? 172 PHE E CE2 1 
ATOM   9339  C  CZ  . PHE E 1 172 ? 63.941  109.241 73.464  1.00 21.30  ? 172 PHE E CZ  1 
ATOM   9340  N  N   . ILE E 1 173 ? 65.125  102.992 76.649  1.00 21.81  ? 173 ILE E N   1 
ATOM   9341  C  CA  . ILE E 1 173 ? 65.194  101.530 76.681  1.00 23.65  ? 173 ILE E CA  1 
ATOM   9342  C  C   . ILE E 1 173 ? 64.108  101.017 75.737  1.00 24.45  ? 173 ILE E C   1 
ATOM   9343  O  O   . ILE E 1 173 ? 62.916  100.995 76.092  1.00 23.20  ? 173 ILE E O   1 
ATOM   9344  C  CB  . ILE E 1 173 ? 65.031  100.969 78.097  1.00 23.64  ? 173 ILE E CB  1 
ATOM   9345  C  CG1 . ILE E 1 173 ? 65.963  101.713 79.058  1.00 24.48  ? 173 ILE E CG1 1 
ATOM   9346  C  CG2 . ILE E 1 173 ? 65.310  99.475  78.130  1.00 20.43  ? 173 ILE E CG2 1 
ATOM   9347  C  CD1 . ILE E 1 173 ? 67.431  101.397 78.877  1.00 23.63  ? 173 ILE E CD1 1 
ATOM   9348  N  N   . PHE E 1 174 ? 64.509  100.613 74.521  1.00 23.86  ? 174 PHE E N   1 
ATOM   9349  C  CA  . PHE E 1 174 ? 63.537  100.183 73.502  1.00 24.28  ? 174 PHE E CA  1 
ATOM   9350  C  C   . PHE E 1 174 ? 62.733  98.970  74.006  1.00 23.58  ? 174 PHE E C   1 
ATOM   9351  O  O   . PHE E 1 174 ? 63.302  97.967  74.443  1.00 24.74  ? 174 PHE E O   1 
ATOM   9352  C  CB  . PHE E 1 174 ? 64.251  99.844  72.174  1.00 23.94  ? 174 PHE E CB  1 
ATOM   9353  C  CG  . PHE E 1 174 ? 64.870  101.058 71.435  1.00 22.53  ? 174 PHE E CG  1 
ATOM   9354  C  CD1 . PHE E 1 174 ? 64.713  102.365 71.899  1.00 20.37  ? 174 PHE E CD1 1 
ATOM   9355  C  CD2 . PHE E 1 174 ? 65.629  100.860 70.280  1.00 23.28  ? 174 PHE E CD2 1 
ATOM   9356  C  CE1 . PHE E 1 174 ? 65.290  103.455 71.201  1.00 23.61  ? 174 PHE E CE1 1 
ATOM   9357  C  CE2 . PHE E 1 174 ? 66.217  101.940 69.583  1.00 20.34  ? 174 PHE E CE2 1 
ATOM   9358  C  CZ  . PHE E 1 174 ? 66.051  103.231 70.046  1.00 21.20  ? 174 PHE E CZ  1 
ATOM   9359  N  N   . THR E 1 175 ? 61.407  99.073  73.958  1.00 19.31  ? 175 THR E N   1 
ATOM   9360  C  CA  . THR E 1 175 ? 60.512  98.007  74.408  1.00 22.79  ? 175 THR E CA  1 
ATOM   9361  C  C   . THR E 1 175 ? 59.407  97.822  73.376  1.00 24.47  ? 175 THR E C   1 
ATOM   9362  O  O   . THR E 1 175 ? 58.241  98.184  73.606  1.00 19.36  ? 175 THR E O   1 
ATOM   9363  C  CB  . THR E 1 175 ? 59.934  98.327  75.791  1.00 21.44  ? 175 THR E CB  1 
ATOM   9364  O  OG1 . THR E 1 175 ? 59.600  99.713  75.834  1.00 18.80  ? 175 THR E OG1 1 
ATOM   9365  C  CG2 . THR E 1 175 ? 60.976  98.043  76.881  1.00 19.58  ? 175 THR E CG2 1 
ATOM   9366  N  N   . PRO E 1 176 ? 59.742  97.258  72.211  1.00 20.90  ? 176 PRO E N   1 
ATOM   9367  C  CA  . PRO E 1 176 ? 58.721  97.071  71.177  1.00 21.31  ? 176 PRO E CA  1 
ATOM   9368  C  C   . PRO E 1 176 ? 57.609  96.187  71.708  1.00 20.29  ? 176 PRO E C   1 
ATOM   9369  O  O   . PRO E 1 176 ? 57.830  95.319  72.547  1.00 21.71  ? 176 PRO E O   1 
ATOM   9370  C  CB  . PRO E 1 176 ? 59.484  96.386  70.031  1.00 19.77  ? 176 PRO E CB  1 
ATOM   9371  C  CG  . PRO E 1 176 ? 60.657  95.708  70.707  1.00 19.95  ? 176 PRO E CG  1 
ATOM   9372  C  CD  . PRO E 1 176 ? 61.037  96.662  71.825  1.00 24.01  ? 176 PRO E CD  1 
ATOM   9373  N  N   . GLY E 1 177 ? 56.404  96.425  71.222  1.00 20.32  ? 177 GLY E N   1 
ATOM   9374  C  CA  . GLY E 1 177 ? 55.346  95.473  71.456  1.00 21.23  ? 177 GLY E CA  1 
ATOM   9375  C  C   . GLY E 1 177 ? 54.004  96.134  71.639  1.00 22.66  ? 177 GLY E C   1 
ATOM   9376  O  O   . GLY E 1 177 ? 53.086  95.931  70.832  1.00 23.25  ? 177 GLY E O   1 
ATOM   9377  N  N   . HIS E 1 178 ? 53.876  96.920  72.711  1.00 21.16  ? 178 HIS E N   1 
ATOM   9378  C  CA  . HIS E 1 178 ? 52.650  97.686  72.897  1.00 25.98  ? 178 HIS E CA  1 
ATOM   9379  C  C   . HIS E 1 178 ? 52.374  98.571  71.689  1.00 23.28  ? 178 HIS E C   1 
ATOM   9380  O  O   . HIS E 1 178 ? 51.243  98.626  71.204  1.00 28.29  ? 178 HIS E O   1 
ATOM   9381  C  CB  . HIS E 1 178 ? 52.726  98.529  74.166  1.00 26.75  ? 178 HIS E CB  1 
ATOM   9382  C  CG  . HIS E 1 178 ? 51.641  99.546  74.245  1.00 30.21  ? 178 HIS E CG  1 
ATOM   9383  N  ND1 . HIS E 1 178 ? 50.332  99.209  74.518  1.00 28.20  ? 178 HIS E ND1 1 
ATOM   9384  C  CD2 . HIS E 1 178 ? 51.652  100.884 74.035  1.00 29.05  ? 178 HIS E CD2 1 
ATOM   9385  C  CE1 . HIS E 1 178 ? 49.590  100.298 74.498  1.00 30.87  ? 178 HIS E CE1 1 
ATOM   9386  N  NE2 . HIS E 1 178 ? 50.366  101.328 74.217  1.00 34.46  ? 178 HIS E NE2 1 
ATOM   9387  N  N   . ALA E 1 179 ? 53.390  99.267  71.192  1.00 22.66  ? 179 ALA E N   1 
ATOM   9388  C  CA  . ALA E 1 179 ? 53.401  99.875  69.869  1.00 23.22  ? 179 ALA E CA  1 
ATOM   9389  C  C   . ALA E 1 179 ? 54.687  99.459  69.161  1.00 22.61  ? 179 ALA E C   1 
ATOM   9390  O  O   . ALA E 1 179 ? 55.638  99.008  69.810  1.00 24.69  ? 179 ALA E O   1 
ATOM   9391  C  CB  . ALA E 1 179 ? 53.309  101.411 69.962  1.00 19.77  ? 179 ALA E CB  1 
ATOM   9392  N  N   . PRO E 1 180 ? 54.761  99.606  67.832  1.00 24.10  ? 180 PRO E N   1 
ATOM   9393  C  CA  . PRO E 1 180 ? 55.985  99.138  67.139  1.00 25.02  ? 180 PRO E CA  1 
ATOM   9394  C  C   . PRO E 1 180 ? 57.246  99.871  67.576  1.00 21.69  ? 180 PRO E C   1 
ATOM   9395  O  O   . PRO E 1 180 ? 58.302  99.241  67.723  1.00 19.44  ? 180 PRO E O   1 
ATOM   9396  C  CB  . PRO E 1 180 ? 55.664  99.366  65.652  1.00 18.81  ? 180 PRO E CB  1 
ATOM   9397  C  CG  . PRO E 1 180 ? 54.181  99.420  65.593  1.00 21.94  ? 180 PRO E CG  1 
ATOM   9398  C  CD  . PRO E 1 180 ? 53.758  100.097 66.872  1.00 19.79  ? 180 PRO E CD  1 
ATOM   9399  N  N   . GLY E 1 181 ? 57.164  101.171 67.839  1.00 20.18  ? 181 GLY E N   1 
ATOM   9400  C  CA  . GLY E 1 181 ? 58.336  101.892 68.292  1.00 19.44  ? 181 GLY E CA  1 
ATOM   9401  C  C   . GLY E 1 181 ? 58.327  102.297 69.750  1.00 21.51  ? 181 GLY E C   1 
ATOM   9402  O  O   . GLY E 1 181 ? 58.947  103.300 70.131  1.00 23.01  ? 181 GLY E O   1 
ATOM   9403  N  N   . HIS E 1 182 ? 57.665  101.509 70.588  1.00 23.10  ? 182 HIS E N   1 
ATOM   9404  C  CA  . HIS E 1 182 ? 57.541  101.884 71.984  1.00 23.11  ? 182 HIS E CA  1 
ATOM   9405  C  C   . HIS E 1 182 ? 58.882  101.794 72.703  1.00 24.09  ? 182 HIS E C   1 
ATOM   9406  O  O   . HIS E 1 182 ? 59.646  100.834 72.539  1.00 22.73  ? 182 HIS E O   1 
ATOM   9407  C  CB  . HIS E 1 182 ? 56.527  101.010 72.715  1.00 23.95  ? 182 HIS E CB  1 
ATOM   9408  C  CG  . HIS E 1 182 ? 56.399  101.368 74.159  1.00 25.90  ? 182 HIS E CG  1 
ATOM   9409  N  ND1 . HIS E 1 182 ? 57.336  100.994 75.102  1.00 20.93  ? 182 HIS E ND1 1 
ATOM   9410  C  CD2 . HIS E 1 182 ? 55.486  102.132 74.812  1.00 25.19  ? 182 HIS E CD2 1 
ATOM   9411  C  CE1 . HIS E 1 182 ? 56.984  101.482 76.280  1.00 26.03  ? 182 HIS E CE1 1 
ATOM   9412  N  NE2 . HIS E 1 182 ? 55.865  102.174 76.132  1.00 25.73  ? 182 HIS E NE2 1 
ATOM   9413  N  N   . SER E 1 183 ? 59.134  102.783 73.541  1.00 20.49  ? 183 SER E N   1 
ATOM   9414  C  CA  . SER E 1 183 ? 60.331  102.839 74.347  1.00 20.37  ? 183 SER E CA  1 
ATOM   9415  C  C   . SER E 1 183 ? 59.942  103.159 75.790  1.00 26.08  ? 183 SER E C   1 
ATOM   9416  O  O   . SER E 1 183 ? 59.026  103.956 76.034  1.00 23.71  ? 183 SER E O   1 
ATOM   9417  C  CB  . SER E 1 183 ? 61.294  103.880 73.763  1.00 19.86  ? 183 SER E CB  1 
ATOM   9418  O  OG  . SER E 1 183 ? 62.578  103.755 74.342  1.00 28.73  ? 183 SER E OG  1 
ATOM   9419  N  N   . SER E 1 184 ? 60.592  102.478 76.736  1.00 22.32  ? 184 SER E N   1 
ATOM   9420  C  CA  . SER E 1 184 ? 60.590  102.847 78.144  1.00 21.55  ? 184 SER E CA  1 
ATOM   9421  C  C   . SER E 1 184 ? 61.789  103.769 78.412  1.00 25.65  ? 184 SER E C   1 
ATOM   9422  O  O   . SER E 1 184 ? 62.571  104.084 77.505  1.00 21.32  ? 184 SER E O   1 
ATOM   9423  C  CB  . SER E 1 184 ? 60.635  101.587 79.011  1.00 20.85  ? 184 SER E CB  1 
ATOM   9424  O  OG  . SER E 1 184 ? 59.598  100.672 78.654  1.00 21.23  ? 184 SER E OG  1 
ATOM   9425  N  N   . PHE E 1 185 ? 61.954  104.214 79.663  1.00 22.72  ? 185 PHE E N   1 
ATOM   9426  C  CA  . PHE E 1 185 ? 63.104  105.048 79.992  1.00 24.06  ? 185 PHE E CA  1 
ATOM   9427  C  C   . PHE E 1 185 ? 63.716  104.624 81.313  1.00 25.09  ? 185 PHE E C   1 
ATOM   9428  O  O   . PHE E 1 185 ? 63.007  104.231 82.245  1.00 27.01  ? 185 PHE E O   1 
ATOM   9429  C  CB  . PHE E 1 185 ? 62.753  106.545 80.050  1.00 24.19  ? 185 PHE E CB  1 
ATOM   9430  C  CG  . PHE E 1 185 ? 62.225  107.088 78.755  1.00 23.77  ? 185 PHE E CG  1 
ATOM   9431  C  CD1 . PHE E 1 185 ? 60.868  107.024 78.467  1.00 20.00  ? 185 PHE E CD1 1 
ATOM   9432  C  CD2 . PHE E 1 185 ? 63.089  107.639 77.814  1.00 22.78  ? 185 PHE E CD2 1 
ATOM   9433  C  CE1 . PHE E 1 185 ? 60.369  107.524 77.263  1.00 22.79  ? 185 PHE E CE1 1 
ATOM   9434  C  CE2 . PHE E 1 185 ? 62.612  108.141 76.611  1.00 21.18  ? 185 PHE E CE2 1 
ATOM   9435  C  CZ  . PHE E 1 185 ? 61.239  108.084 76.330  1.00 21.80  ? 185 PHE E CZ  1 
ATOM   9436  N  N   . LEU E 1 186 ? 65.044  104.683 81.366  1.00 25.10  ? 186 LEU E N   1 
ATOM   9437  C  CA  . LEU E 1 186 ? 65.822  104.444 82.576  1.00 25.82  ? 186 LEU E CA  1 
ATOM   9438  C  C   . LEU E 1 186 ? 66.473  105.750 83.015  1.00 26.82  ? 186 LEU E C   1 
ATOM   9439  O  O   . LEU E 1 186 ? 67.333  106.291 82.307  1.00 26.73  ? 186 LEU E O   1 
ATOM   9440  C  CB  . LEU E 1 186 ? 66.892  103.378 82.344  1.00 23.28  ? 186 LEU E CB  1 
ATOM   9441  C  CG  . LEU E 1 186 ? 67.833  103.204 83.533  1.00 25.47  ? 186 LEU E CG  1 
ATOM   9442  C  CD1 . LEU E 1 186 ? 67.093  102.555 84.696  1.00 25.93  ? 186 LEU E CD1 1 
ATOM   9443  C  CD2 . LEU E 1 186 ? 69.072  102.376 83.158  1.00 28.11  ? 186 LEU E CD2 1 
ATOM   9444  N  N   . LEU E 1 187 ? 66.074  106.243 84.179  1.00 27.74  ? 187 LEU E N   1 
ATOM   9445  C  CA  . LEU E 1 187 ? 66.607  107.480 84.731  1.00 27.25  ? 187 LEU E CA  1 
ATOM   9446  C  C   . LEU E 1 187 ? 67.594  107.151 85.835  1.00 28.05  ? 187 LEU E C   1 
ATOM   9447  O  O   . LEU E 1 187 ? 67.465  106.133 86.514  1.00 31.53  ? 187 LEU E O   1 
ATOM   9448  C  CB  . LEU E 1 187 ? 65.485  108.366 85.285  1.00 28.42  ? 187 LEU E CB  1 
ATOM   9449  C  CG  . LEU E 1 187 ? 64.657  109.217 84.316  1.00 32.46  ? 187 LEU E CG  1 
ATOM   9450  C  CD1 . LEU E 1 187 ? 64.125  108.406 83.159  1.00 30.11  ? 187 LEU E CD1 1 
ATOM   9451  C  CD2 . LEU E 1 187 ? 63.482  109.855 85.037  1.00 37.22  ? 187 LEU E CD2 1 
ATOM   9452  N  N   . ARG E 1 188 ? 68.600  108.004 86.003  1.00 30.85  ? 188 ARG E N   1 
ATOM   9453  C  CA  . ARG E 1 188 ? 69.495  107.916 87.154  1.00 30.11  ? 188 ARG E CA  1 
ATOM   9454  C  C   . ARG E 1 188 ? 69.537  109.280 87.818  1.00 35.05  ? 188 ARG E C   1 
ATOM   9455  O  O   . ARG E 1 188 ? 69.909  110.268 87.178  1.00 34.64  ? 188 ARG E O   1 
ATOM   9456  C  CB  . ARG E 1 188 ? 70.905  107.472 86.758  1.00 30.32  ? 188 ARG E CB  1 
ATOM   9457  C  CG  . ARG E 1 188 ? 70.983  105.998 86.409  1.00 36.41  ? 188 ARG E CG  1 
ATOM   9458  C  CD  . ARG E 1 188 ? 72.420  105.557 86.185  1.00 33.28  ? 188 ARG E CD  1 
ATOM   9459  N  NE  . ARG E 1 188 ? 72.454  104.189 85.690  1.00 35.44  ? 188 ARG E NE  1 
ATOM   9460  C  CZ  . ARG E 1 188 ? 72.471  103.112 86.465  1.00 39.72  ? 188 ARG E CZ  1 
ATOM   9461  N  NH1 . ARG E 1 188 ? 72.528  103.209 87.785  1.00 38.74  ? 188 ARG E NH1 1 
ATOM   9462  N  NH2 . ARG E 1 188 ? 72.439  101.906 85.900  1.00 37.59  ? 188 ARG E NH2 1 
ATOM   9463  N  N   . LEU E 1 189 ? 69.164  109.327 89.096  1.00 33.99  ? 189 LEU E N   1 
ATOM   9464  C  CA  . LEU E 1 189 ? 69.112  110.563 89.847  1.00 33.64  ? 189 LEU E CA  1 
ATOM   9465  C  C   . LEU E 1 189 ? 70.055  110.500 91.044  1.00 35.22  ? 189 LEU E C   1 
ATOM   9466  O  O   . LEU E 1 189 ? 70.247  109.431 91.632  1.00 35.55  ? 189 LEU E O   1 
ATOM   9467  C  CB  . LEU E 1 189 ? 67.677  110.839 90.310  1.00 36.39  ? 189 LEU E CB  1 
ATOM   9468  C  CG  . LEU E 1 189 ? 66.804  110.986 89.064  1.00 36.56  ? 189 LEU E CG  1 
ATOM   9469  C  CD1 . LEU E 1 189 ? 65.358  110.913 89.414  1.00 34.61  ? 189 LEU E CD1 1 
ATOM   9470  C  CD2 . LEU E 1 189 ? 67.132  112.313 88.370  1.00 36.05  ? 189 LEU E CD2 1 
ATOM   9471  N  N   . PRO E 1 190 ? 70.671  111.634 91.406  1.00 33.48  ? 190 PRO E N   1 
ATOM   9472  C  CA  . PRO E 1 190 ? 71.733  111.625 92.436  1.00 35.60  ? 190 PRO E CA  1 
ATOM   9473  C  C   . PRO E 1 190 ? 71.369  110.900 93.715  1.00 36.62  ? 190 PRO E C   1 
ATOM   9474  O  O   . PRO E 1 190 ? 72.192  110.147 94.244  1.00 35.98  ? 190 PRO E O   1 
ATOM   9475  C  CB  . PRO E 1 190 ? 71.966  113.119 92.704  1.00 36.60  ? 190 PRO E CB  1 
ATOM   9476  C  CG  . PRO E 1 190 ? 71.576  113.800 91.405  1.00 41.73  ? 190 PRO E CG  1 
ATOM   9477  C  CD  . PRO E 1 190 ? 70.480  112.960 90.789  1.00 34.83  ? 190 PRO E CD  1 
ATOM   9478  N  N   . GLU E 1 191 ? 70.156  111.096 94.228  1.00 35.70  ? 191 GLU E N   1 
ATOM   9479  C  CA  . GLU E 1 191 ? 69.757  110.532 95.509  1.00 35.04  ? 191 GLU E CA  1 
ATOM   9480  C  C   . GLU E 1 191 ? 68.958  109.251 95.350  1.00 37.91  ? 191 GLU E C   1 
ATOM   9481  O  O   . GLU E 1 191 ? 69.272  108.240 95.984  1.00 39.89  ? 191 GLU E O   1 
ATOM   9482  C  CB  . GLU E 1 191 ? 68.925  111.550 96.305  1.00 38.93  ? 191 GLU E CB  1 
ATOM   9483  C  CG  . GLU E 1 191 ? 69.699  112.734 96.867  1.00 44.35  ? 191 GLU E CG  1 
ATOM   9484  C  CD  . GLU E 1 191 ? 68.797  113.687 97.642  1.00 48.10  ? 191 GLU E CD  1 
ATOM   9485  O  OE1 . GLU E 1 191 ? 67.899  113.206 98.371  1.00 48.76  ? 191 GLU E OE1 1 
ATOM   9486  O  OE2 . GLU E 1 191 ? 68.982  114.913 97.519  1.00 49.29  ? 191 GLU E OE2 1 
ATOM   9487  N  N   . THR E 1 192 ? 67.913  109.281 94.519  1.00 36.07  ? 192 THR E N   1 
ATOM   9488  C  CA  . THR E 1 192 ? 67.078  108.100 94.337  1.00 33.15  ? 192 THR E CA  1 
ATOM   9489  C  C   . THR E 1 192 ? 67.844  106.968 93.676  1.00 32.89  ? 192 THR E C   1 
ATOM   9490  O  O   . THR E 1 192 ? 67.559  105.791 93.939  1.00 35.23  ? 192 THR E O   1 
ATOM   9491  C  CB  . THR E 1 192 ? 65.855  108.458 93.497  1.00 32.93  ? 192 THR E CB  1 
ATOM   9492  O  OG1 . THR E 1 192 ? 65.268  109.661 94.006  1.00 34.55  ? 192 THR E OG1 1 
ATOM   9493  C  CG2 . THR E 1 192 ? 64.830  107.342 93.507  1.00 28.16  ? 192 THR E CG2 1 
ATOM   9494  N  N   . GLY E 1 193 ? 68.821  107.295 92.833  1.00 28.61  ? 193 GLY E N   1 
ATOM   9495  C  CA  . GLY E 1 193 ? 69.448  106.296 91.998  1.00 28.85  ? 193 GLY E CA  1 
ATOM   9496  C  C   . GLY E 1 193 ? 68.600  106.026 90.766  1.00 30.15  ? 193 GLY E C   1 
ATOM   9497  O  O   . GLY E 1 193 ? 68.036  106.943 90.163  1.00 30.70  ? 193 GLY E O   1 
ATOM   9498  N  N   . PRO E 1 194 ? 68.489  104.762 90.372  1.00 29.75  ? 194 PRO E N   1 
ATOM   9499  C  CA  . PRO E 1 194 ? 67.851  104.449 89.092  1.00 28.69  ? 194 PRO E CA  1 
ATOM   9500  C  C   . PRO E 1 194 ? 66.344  104.317 89.204  1.00 29.34  ? 194 PRO E C   1 
ATOM   9501  O  O   . PRO E 1 194 ? 65.816  103.668 90.109  1.00 27.35  ? 194 PRO E O   1 
ATOM   9502  C  CB  . PRO E 1 194 ? 68.486  103.109 88.709  1.00 27.22  ? 194 PRO E CB  1 
ATOM   9503  C  CG  . PRO E 1 194 ? 68.807  102.482 90.013  1.00 29.98  ? 194 PRO E CG  1 
ATOM   9504  C  CD  . PRO E 1 194 ? 69.124  103.576 90.974  1.00 28.91  ? 194 PRO E CD  1 
ATOM   9505  N  N   . VAL E 1 195 ? 65.660  104.908 88.234  1.00 26.44  ? 195 VAL E N   1 
ATOM   9506  C  CA  . VAL E 1 195 ? 64.212  104.842 88.114  1.00 28.30  ? 195 VAL E CA  1 
ATOM   9507  C  C   . VAL E 1 195 ? 63.894  104.302 86.726  1.00 26.61  ? 195 VAL E C   1 
ATOM   9508  O  O   . VAL E 1 195 ? 64.357  104.856 85.723  1.00 28.33  ? 195 VAL E O   1 
ATOM   9509  C  CB  . VAL E 1 195 ? 63.568  106.227 88.334  1.00 25.21  ? 195 VAL E CB  1 
ATOM   9510  C  CG1 . VAL E 1 195 ? 62.059  106.136 88.260  1.00 24.05  ? 195 VAL E CG1 1 
ATOM   9511  C  CG2 . VAL E 1 195 ? 64.003  106.804 89.672  1.00 30.06  ? 195 VAL E CG2 1 
ATOM   9512  N  N   . LEU E 1 196 ? 63.109  103.229 86.667  1.00 29.84  ? 196 LEU E N   1 
ATOM   9513  C  CA  . LEU E 1 196 ? 62.750  102.583 85.406  1.00 26.58  ? 196 LEU E CA  1 
ATOM   9514  C  C   . LEU E 1 196 ? 61.309  102.950 85.078  1.00 28.99  ? 196 LEU E C   1 
ATOM   9515  O  O   . LEU E 1 196 ? 60.365  102.404 85.663  1.00 27.09  ? 196 LEU E O   1 
ATOM   9516  C  CB  . LEU E 1 196 ? 62.941  101.068 85.477  1.00 26.89  ? 196 LEU E CB  1 
ATOM   9517  C  CG  . LEU E 1 196 ? 62.430  100.246 84.281  1.00 28.08  ? 196 LEU E CG  1 
ATOM   9518  C  CD1 . LEU E 1 196 ? 63.006  100.789 83.006  1.00 27.49  ? 196 LEU E CD1 1 
ATOM   9519  C  CD2 . LEU E 1 196 ? 62.749  98.736  84.420  1.00 25.92  ? 196 LEU E CD2 1 
ATOM   9520  N  N   . LEU E 1 197 ? 61.147  103.880 84.143  1.00 25.85  ? 197 LEU E N   1 
ATOM   9521  C  CA  . LEU E 1 197 ? 59.830  104.281 83.671  1.00 25.76  ? 197 LEU E CA  1 
ATOM   9522  C  C   . LEU E 1 197 ? 59.388  103.274 82.617  1.00 25.17  ? 197 LEU E C   1 
ATOM   9523  O  O   . LEU E 1 197 ? 59.776  103.368 81.452  1.00 26.98  ? 197 LEU E O   1 
ATOM   9524  C  CB  . LEU E 1 197 ? 59.868  105.699 83.112  1.00 26.15  ? 197 LEU E CB  1 
ATOM   9525  C  CG  . LEU E 1 197 ? 60.316  106.791 84.081  1.00 30.24  ? 197 LEU E CG  1 
ATOM   9526  C  CD1 . LEU E 1 197 ? 60.191  108.153 83.427  1.00 24.04  ? 197 LEU E CD1 1 
ATOM   9527  C  CD2 . LEU E 1 197 ? 59.480  106.709 85.330  1.00 29.35  ? 197 LEU E CD2 1 
ATOM   9528  N  N   . ALA E 1 198 ? 58.582  102.295 83.029  1.00 25.50  ? 198 ALA E N   1 
ATOM   9529  C  CA  . ALA E 1 198 ? 58.154  101.259 82.099  1.00 27.78  ? 198 ALA E CA  1 
ATOM   9530  C  C   . ALA E 1 198 ? 57.238  101.806 81.016  1.00 27.60  ? 198 ALA E C   1 
ATOM   9531  O  O   . ALA E 1 198 ? 57.216  101.260 79.910  1.00 28.56  ? 198 ALA E O   1 
ATOM   9532  C  CB  . ALA E 1 198 ? 57.442  100.134 82.842  1.00 25.61  ? 198 ALA E CB  1 
ATOM   9533  N  N   . VAL E 1 199 ? 56.500  102.884 81.306  1.00 25.62  ? 199 VAL E N   1 
ATOM   9534  C  CA  . VAL E 1 199 ? 55.405  103.375 80.470  1.00 24.54  ? 199 VAL E CA  1 
ATOM   9535  C  C   . VAL E 1 199 ? 54.527  102.193 80.061  1.00 25.93  ? 199 VAL E C   1 
ATOM   9536  O  O   . VAL E 1 199 ? 54.215  101.335 80.893  1.00 27.47  ? 199 VAL E O   1 
ATOM   9537  C  CB  . VAL E 1 199 ? 55.929  104.184 79.264  1.00 23.86  ? 199 VAL E CB  1 
ATOM   9538  C  CG1 . VAL E 1 199 ? 54.825  105.055 78.666  1.00 22.49  ? 199 VAL E CG1 1 
ATOM   9539  C  CG2 . VAL E 1 199 ? 57.063  105.100 79.714  1.00 22.37  ? 199 VAL E CG2 1 
ATOM   9540  N  N   . ASP E 1 200 ? 54.140  102.104 78.789  1.00 27.31  ? 200 ASP E N   1 
ATOM   9541  C  CA  . ASP E 1 200 ? 53.131  101.132 78.386  1.00 29.01  ? 200 ASP E CA  1 
ATOM   9542  C  C   . ASP E 1 200 ? 53.701  99.772  78.021  1.00 26.51  ? 200 ASP E C   1 
ATOM   9543  O  O   . ASP E 1 200 ? 52.953  98.924  77.518  1.00 22.95  ? 200 ASP E O   1 
ATOM   9544  C  CB  . ASP E 1 200 ? 52.301  101.670 77.221  1.00 27.79  ? 200 ASP E CB  1 
ATOM   9545  C  CG  . ASP E 1 200 ? 51.415  102.820 77.636  1.00 30.90  ? 200 ASP E CG  1 
ATOM   9546  O  OD1 . ASP E 1 200 ? 51.544  103.297 78.783  1.00 33.62  ? 200 ASP E OD1 1 
ATOM   9547  O  OD2 . ASP E 1 200 ? 50.576  103.221 76.834  1.00 29.42  ? 200 ASP E OD2 1 
ATOM   9548  N  N   . ALA E 1 201 ? 54.993  99.542  78.259  1.00 26.40  ? 201 ALA E N   1 
ATOM   9549  C  CA  . ALA E 1 201 ? 55.510  98.181  78.133  1.00 25.54  ? 201 ALA E CA  1 
ATOM   9550  C  C   . ALA E 1 201 ? 54.928  97.275  79.213  1.00 24.78  ? 201 ALA E C   1 
ATOM   9551  O  O   . ALA E 1 201 ? 54.777  96.069  78.999  1.00 22.51  ? 201 ALA E O   1 
ATOM   9552  C  CB  . ALA E 1 201 ? 57.037  98.187  78.200  1.00 21.88  ? 201 ALA E CB  1 
ATOM   9553  N  N   . ALA E 1 202 ? 54.596  97.845  80.367  1.00 23.57  ? 202 ALA E N   1 
ATOM   9554  C  CA  . ALA E 1 202 ? 54.002  97.115  81.492  1.00 26.83  ? 202 ALA E CA  1 
ATOM   9555  C  C   . ALA E 1 202 ? 52.983  98.045  82.153  1.00 29.20  ? 202 ALA E C   1 
ATOM   9556  O  O   . ALA E 1 202 ? 53.336  98.882  82.990  1.00 27.24  ? 202 ALA E O   1 
ATOM   9557  C  CB  . ALA E 1 202 ? 55.056  96.657  82.484  1.00 24.18  ? 202 ALA E CB  1 
ATOM   9558  N  N   . TYR E 1 203 ? 51.722  97.889  81.750  1.00 32.22  ? 203 TYR E N   1 
ATOM   9559  C  CA  . TYR E 1 203 ? 50.622  98.702  82.255  1.00 36.44  ? 203 TYR E CA  1 
ATOM   9560  C  C   . TYR E 1 203 ? 50.538  98.673  83.780  1.00 37.44  ? 203 TYR E C   1 
ATOM   9561  O  O   . TYR E 1 203 ? 50.406  99.719  84.427  1.00 34.79  ? 203 TYR E O   1 
ATOM   9562  C  CB  . TYR E 1 203 ? 49.320  98.178  81.660  1.00 36.50  ? 203 TYR E CB  1 
ATOM   9563  C  CG  . TYR E 1 203 ? 48.929  98.720  80.310  1.00 39.02  ? 203 TYR E CG  1 
ATOM   9564  C  CD1 . TYR E 1 203 ? 49.386  99.955  79.860  1.00 38.96  ? 203 TYR E CD1 1 
ATOM   9565  C  CD2 . TYR E 1 203 ? 48.070  97.994  79.489  1.00 39.58  ? 203 TYR E CD2 1 
ATOM   9566  C  CE1 . TYR E 1 203 ? 48.991  100.448 78.622  1.00 40.47  ? 203 TYR E CE1 1 
ATOM   9567  C  CE2 . TYR E 1 203 ? 47.676  98.471  78.255  1.00 42.40  ? 203 TYR E CE2 1 
ATOM   9568  C  CZ  . TYR E 1 203 ? 48.132  99.699  77.826  1.00 44.24  ? 203 TYR E CZ  1 
ATOM   9569  O  OH  . TYR E 1 203 ? 47.714  100.161 76.598  1.00 44.70  ? 203 TYR E OH  1 
ATOM   9570  N  N   . THR E 1 204 ? 50.585  97.472  84.366  1.00 32.71  ? 204 THR E N   1 
ATOM   9571  C  CA  . THR E 1 204 ? 50.338  97.242  85.786  1.00 36.65  ? 204 THR E CA  1 
ATOM   9572  C  C   . THR E 1 204 ? 51.296  96.175  86.299  1.00 38.11  ? 204 THR E C   1 
ATOM   9573  O  O   . THR E 1 204 ? 52.048  95.568  85.529  1.00 36.26  ? 204 THR E O   1 
ATOM   9574  C  CB  . THR E 1 204 ? 48.906  96.764  86.039  1.00 37.45  ? 204 THR E CB  1 
ATOM   9575  O  OG1 . THR E 1 204 ? 48.764  95.442  85.503  1.00 39.11  ? 204 THR E OG1 1 
ATOM   9576  C  CG2 . THR E 1 204 ? 47.882  97.691  85.396  1.00 40.02  ? 204 THR E CG2 1 
ATOM   9577  N  N   . THR E 1 205 ? 51.224  95.902  87.610  1.00 35.65  ? 205 THR E N   1 
ATOM   9578  C  CA  . THR E 1 205 ? 52.040  94.829  88.175  1.00 38.31  ? 205 THR E CA  1 
ATOM   9579  C  C   . THR E 1 205 ? 51.652  93.467  87.609  1.00 37.98  ? 205 THR E C   1 
ATOM   9580  O  O   . THR E 1 205 ? 52.506  92.580  87.498  1.00 36.07  ? 205 THR E O   1 
ATOM   9581  C  CB  . THR E 1 205 ? 51.944  94.800  89.705  1.00 38.04  ? 205 THR E CB  1 
ATOM   9582  O  OG1 . THR E 1 205 ? 50.568  94.740  90.109  1.00 41.94  ? 205 THR E OG1 1 
ATOM   9583  C  CG2 . THR E 1 205 ? 52.585  96.018  90.284  1.00 38.50  ? 205 THR E CG2 1 
ATOM   9584  N  N   . ASP E 1 206 ? 50.379  93.280  87.246  1.00 37.70  ? 206 ASP E N   1 
ATOM   9585  C  CA  . ASP E 1 206 ? 49.960  92.001  86.679  1.00 38.66  ? 206 ASP E CA  1 
ATOM   9586  C  C   . ASP E 1 206 ? 50.688  91.705  85.373  1.00 35.42  ? 206 ASP E C   1 
ATOM   9587  O  O   . ASP E 1 206 ? 51.069  90.556  85.115  1.00 33.35  ? 206 ASP E O   1 
ATOM   9588  C  CB  . ASP E 1 206 ? 48.448  91.987  86.461  1.00 41.53  ? 206 ASP E CB  1 
ATOM   9589  C  CG  . ASP E 1 206 ? 47.683  91.450  87.670  1.00 48.74  ? 206 ASP E CG  1 
ATOM   9590  O  OD1 . ASP E 1 206 ? 48.310  91.140  88.716  1.00 48.43  ? 206 ASP E OD1 1 
ATOM   9591  O  OD2 . ASP E 1 206 ? 46.446  91.324  87.560  1.00 44.20  ? 206 ASP E OD2 1 
ATOM   9592  N  N   . HIS E 1 207 ? 50.856  92.722  84.523  1.00 34.31  ? 207 HIS E N   1 
ATOM   9593  C  CA  . HIS E 1 207 ? 51.644  92.559  83.305  1.00 34.85  ? 207 HIS E CA  1 
ATOM   9594  C  C   . HIS E 1 207 ? 53.092  92.252  83.647  1.00 33.25  ? 207 HIS E C   1 
ATOM   9595  O  O   . HIS E 1 207 ? 53.693  91.329  83.080  1.00 31.84  ? 207 HIS E O   1 
ATOM   9596  C  CB  . HIS E 1 207 ? 51.569  93.821  82.445  1.00 36.18  ? 207 HIS E CB  1 
ATOM   9597  C  CG  . HIS E 1 207 ? 50.203  94.122  81.923  1.00 38.74  ? 207 HIS E CG  1 
ATOM   9598  N  ND1 . HIS E 1 207 ? 49.279  94.864  82.632  1.00 39.87  ? 207 HIS E ND1 1 
ATOM   9599  C  CD2 . HIS E 1 207 ? 49.607  93.796  80.750  1.00 39.35  ? 207 HIS E CD2 1 
ATOM   9600  C  CE1 . HIS E 1 207 ? 48.169  94.972  81.922  1.00 40.72  ? 207 HIS E CE1 1 
ATOM   9601  N  NE2 . HIS E 1 207 ? 48.341  94.330  80.777  1.00 39.66  ? 207 HIS E NE2 1 
ATOM   9602  N  N   . TRP E 1 208 ? 53.660  93.018  84.590  1.00 30.87  ? 208 TRP E N   1 
ATOM   9603  C  CA  . TRP E 1 208 ? 55.040  92.803  85.016  1.00 30.55  ? 208 TRP E CA  1 
ATOM   9604  C  C   . TRP E 1 208 ? 55.234  91.390  85.539  1.00 32.33  ? 208 TRP E C   1 
ATOM   9605  O  O   . TRP E 1 208 ? 56.290  90.778  85.317  1.00 30.35  ? 208 TRP E O   1 
ATOM   9606  C  CB  . TRP E 1 208 ? 55.434  93.830  86.080  1.00 32.56  ? 208 TRP E CB  1 
ATOM   9607  C  CG  . TRP E 1 208 ? 56.894  93.769  86.492  1.00 30.05  ? 208 TRP E CG  1 
ATOM   9608  C  CD1 . TRP E 1 208 ? 57.434  93.002  87.484  1.00 30.93  ? 208 TRP E CD1 1 
ATOM   9609  C  CD2 . TRP E 1 208 ? 57.986  94.495  85.909  1.00 27.95  ? 208 TRP E CD2 1 
ATOM   9610  N  NE1 . TRP E 1 208 ? 58.792  93.204  87.554  1.00 31.73  ? 208 TRP E NE1 1 
ATOM   9611  C  CE2 . TRP E 1 208 ? 59.156  94.119  86.604  1.00 27.54  ? 208 TRP E CE2 1 
ATOM   9612  C  CE3 . TRP E 1 208 ? 58.086  95.425  84.871  1.00 25.73  ? 208 TRP E CE3 1 
ATOM   9613  C  CZ2 . TRP E 1 208 ? 60.410  94.641  86.296  1.00 32.22  ? 208 TRP E CZ2 1 
ATOM   9614  C  CZ3 . TRP E 1 208 ? 59.328  95.945  84.564  1.00 27.91  ? 208 TRP E CZ3 1 
ATOM   9615  C  CH2 . TRP E 1 208 ? 60.480  95.548  85.269  1.00 30.11  ? 208 TRP E CH2 1 
ATOM   9616  N  N   . ASP E 1 209 ? 54.220  90.842  86.204  1.00 27.97  ? 209 ASP E N   1 
ATOM   9617  C  CA  . ASP E 1 209 ? 54.302  89.502  86.768  1.00 32.99  ? 209 ASP E CA  1 
ATOM   9618  C  C   . ASP E 1 209 ? 53.818  88.438  85.804  1.00 35.05  ? 209 ASP E C   1 
ATOM   9619  O  O   . ASP E 1 209 ? 53.661  87.281  86.212  1.00 35.65  ? 209 ASP E O   1 
ATOM   9620  C  CB  . ASP E 1 209 ? 53.489  89.406  88.062  1.00 37.43  ? 209 ASP E CB  1 
ATOM   9621  C  CG  . ASP E 1 209 ? 54.035  90.288  89.164  1.00 39.44  ? 209 ASP E CG  1 
ATOM   9622  O  OD1 . ASP E 1 209 ? 55.233  90.636  89.121  1.00 39.41  ? 209 ASP E OD1 1 
ATOM   9623  O  OD2 . ASP E 1 209 ? 53.260  90.632  90.078  1.00 44.86  ? 209 ASP E OD2 1 
ATOM   9624  N  N   . GLU E 1 210 ? 53.560  88.811  84.546  1.00 34.49  ? 210 GLU E N   1 
ATOM   9625  C  CA  . GLU E 1 210 ? 53.153  87.867  83.496  1.00 34.97  ? 210 GLU E CA  1 
ATOM   9626  C  C   . GLU E 1 210 ? 51.830  87.177  83.843  1.00 36.23  ? 210 GLU E C   1 
ATOM   9627  O  O   . GLU E 1 210 ? 51.634  85.993  83.568  1.00 38.74  ? 210 GLU E O   1 
ATOM   9628  C  CB  . GLU E 1 210 ? 54.271  86.849  83.210  1.00 26.94  ? 210 GLU E CB  1 
ATOM   9629  C  CG  . GLU E 1 210 ? 55.587  87.559  82.932  1.00 28.42  ? 210 GLU E CG  1 
ATOM   9630  C  CD  . GLU E 1 210 ? 56.709  86.648  82.481  1.00 31.54  ? 210 GLU E CD  1 
ATOM   9631  O  OE1 . GLU E 1 210 ? 56.601  85.415  82.650  1.00 32.72  ? 210 GLU E OE1 1 
ATOM   9632  O  OE2 . GLU E 1 210 ? 57.705  87.175  81.928  1.00 29.19  ? 210 GLU E OE2 1 
ATOM   9633  N  N   . LYS E 1 211 ? 50.913  87.928  84.461  1.00 38.01  ? 211 LYS E N   1 
ATOM   9634  C  CA  . LYS E 1 211 ? 49.552  87.475  84.715  1.00 37.28  ? 211 LYS E CA  1 
ATOM   9635  C  C   . LYS E 1 211 ? 48.543  88.146  83.794  1.00 40.66  ? 211 LYS E C   1 
ATOM   9636  O  O   . LYS E 1 211 ? 47.339  87.901  83.930  1.00 43.22  ? 211 LYS E O   1 
ATOM   9637  C  CB  . LYS E 1 211 ? 49.165  87.737  86.174  1.00 39.43  ? 211 LYS E CB  1 
ATOM   9638  C  CG  . LYS E 1 211 ? 50.256  87.422  87.192  1.00 42.28  ? 211 LYS E CG  1 
ATOM   9639  C  CD  . LYS E 1 211 ? 50.421  85.929  87.426  1.00 44.53  ? 211 LYS E CD  1 
ATOM   9640  C  CE  . LYS E 1 211 ? 49.167  85.316  88.041  1.00 57.15  ? 211 LYS E CE  1 
ATOM   9641  N  NZ  . LYS E 1 211 ? 49.431  83.956  88.610  1.00 66.52  ? 211 LYS E NZ  1 
ATOM   9642  N  N   . ALA E 1 212 ? 49.002  89.006  82.883  1.00 36.38  ? 212 ALA E N   1 
ATOM   9643  C  CA  . ALA E 1 212 ? 48.131  89.675  81.929  1.00 36.75  ? 212 ALA E CA  1 
ATOM   9644  C  C   . ALA E 1 212 ? 48.940  90.035  80.690  1.00 36.35  ? 212 ALA E C   1 
ATOM   9645  O  O   . ALA E 1 212 ? 50.156  90.222  80.765  1.00 38.35  ? 212 ALA E O   1 
ATOM   9646  C  CB  . ALA E 1 212 ? 47.502  90.936  82.538  1.00 41.01  ? 212 ALA E CB  1 
ATOM   9647  N  N   . LEU E 1 213 ? 48.255  90.129  79.557  1.00 30.51  ? 213 LEU E N   1 
ATOM   9648  C  CA  . LEU E 1 213 ? 48.788  90.738  78.353  1.00 35.26  ? 213 LEU E CA  1 
ATOM   9649  C  C   . LEU E 1 213 ? 48.163  92.113  78.155  1.00 35.13  ? 213 LEU E C   1 
ATOM   9650  O  O   . LEU E 1 213 ? 47.053  92.357  78.630  1.00 36.20  ? 213 LEU E O   1 
ATOM   9651  C  CB  . LEU E 1 213 ? 48.504  89.875  77.113  1.00 35.01  ? 213 LEU E CB  1 
ATOM   9652  C  CG  . LEU E 1 213 ? 49.109  88.469  77.111  1.00 29.65  ? 213 LEU E CG  1 
ATOM   9653  C  CD1 . LEU E 1 213 ? 48.611  87.638  75.945  1.00 26.27  ? 213 LEU E CD1 1 
ATOM   9654  C  CD2 . LEU E 1 213 ? 50.613  88.543  77.112  1.00 25.40  ? 213 LEU E CD2 1 
ATOM   9655  N  N   . PRO E 1 214 ? 48.840  93.040  77.471  1.00 36.95  ? 214 PRO E N   1 
ATOM   9656  C  CA  . PRO E 1 214 ? 48.198  94.322  77.161  1.00 37.23  ? 214 PRO E CA  1 
ATOM   9657  C  C   . PRO E 1 214 ? 46.937  94.097  76.343  1.00 42.80  ? 214 PRO E C   1 
ATOM   9658  O  O   . PRO E 1 214 ? 46.891  93.229  75.465  1.00 39.25  ? 214 PRO E O   1 
ATOM   9659  C  CB  . PRO E 1 214 ? 49.257  95.080  76.350  1.00 39.52  ? 214 PRO E CB  1 
ATOM   9660  C  CG  . PRO E 1 214 ? 50.525  94.335  76.533  1.00 35.71  ? 214 PRO E CG  1 
ATOM   9661  C  CD  . PRO E 1 214 ? 50.190  92.935  76.896  1.00 34.98  ? 214 PRO E CD  1 
ATOM   9662  N  N   . GLY E 1 215 ? 45.902  94.884  76.651  1.00 40.66  ? 215 GLY E N   1 
ATOM   9663  C  CA  . GLY E 1 215 ? 44.668  94.838  75.897  1.00 38.33  ? 215 GLY E CA  1 
ATOM   9664  C  C   . GLY E 1 215 ? 44.717  95.517  74.554  1.00 38.78  ? 215 GLY E C   1 
ATOM   9665  O  O   . GLY E 1 215 ? 43.815  95.314  73.738  1.00 44.24  ? 215 GLY E O   1 
ATOM   9666  N  N   . PHE E 1 216 ? 45.729  96.344  74.311  1.00 39.03  ? 216 PHE E N   1 
ATOM   9667  C  CA  . PHE E 1 216 ? 45.992  96.912  72.997  1.00 40.22  ? 216 PHE E CA  1 
ATOM   9668  C  C   . PHE E 1 216 ? 47.477  96.724  72.704  1.00 41.91  ? 216 PHE E C   1 
ATOM   9669  O  O   . PHE E 1 216 ? 48.320  97.111  73.521  1.00 37.56  ? 216 PHE E O   1 
ATOM   9670  C  CB  . PHE E 1 216 ? 45.610  98.396  72.930  1.00 39.58  ? 216 PHE E CB  1 
ATOM   9671  C  CG  . PHE E 1 216 ? 45.955  99.035  71.620  1.00 46.61  ? 216 PHE E CG  1 
ATOM   9672  C  CD1 . PHE E 1 216 ? 47.259  99.421  71.334  1.00 47.43  ? 216 PHE E CD1 1 
ATOM   9673  C  CD2 . PHE E 1 216 ? 44.987  99.199  70.642  1.00 45.53  ? 216 PHE E CD2 1 
ATOM   9674  C  CE1 . PHE E 1 216 ? 47.574  99.976  70.113  1.00 50.88  ? 216 PHE E CE1 1 
ATOM   9675  C  CE2 . PHE E 1 216 ? 45.302  99.766  69.420  1.00 40.49  ? 216 PHE E CE2 1 
ATOM   9676  C  CZ  . PHE E 1 216 ? 46.587  100.151 69.155  1.00 44.77  ? 216 PHE E CZ  1 
ATOM   9677  N  N   . LEU E 1 217 ? 47.805  96.143  71.548  1.00 35.29  ? 217 LEU E N   1 
ATOM   9678  C  CA  . LEU E 1 217 ? 49.204  95.847  71.279  1.00 30.72  ? 217 LEU E CA  1 
ATOM   9679  C  C   . LEU E 1 217 ? 49.435  95.558  69.802  1.00 29.26  ? 217 LEU E C   1 
ATOM   9680  O  O   . LEU E 1 217 ? 48.580  95.005  69.108  1.00 29.10  ? 217 LEU E O   1 
ATOM   9681  C  CB  . LEU E 1 217 ? 49.693  94.677  72.127  1.00 29.52  ? 217 LEU E CB  1 
ATOM   9682  C  CG  . LEU E 1 217 ? 49.312  93.258  71.733  1.00 30.93  ? 217 LEU E CG  1 
ATOM   9683  C  CD1 . LEU E 1 217 ? 49.911  92.323  72.766  1.00 30.35  ? 217 LEU E CD1 1 
ATOM   9684  C  CD2 . LEU E 1 217 ? 47.804  93.056  71.614  1.00 32.52  ? 217 LEU E CD2 1 
ATOM   9685  N  N   . ALA E 1 218 ? 50.609  95.964  69.335  1.00 24.11  ? 218 ALA E N   1 
ATOM   9686  C  CA  . ALA E 1 218 ? 50.996  95.672  67.964  1.00 23.65  ? 218 ALA E CA  1 
ATOM   9687  C  C   . ALA E 1 218 ? 51.496  94.234  67.830  1.00 21.76  ? 218 ALA E C   1 
ATOM   9688  O  O   . ALA E 1 218 ? 51.145  93.555  66.861  1.00 23.97  ? 218 ALA E O   1 
ATOM   9689  C  CB  . ALA E 1 218 ? 52.063  96.674  67.490  1.00 18.93  ? 218 ALA E CB  1 
ATOM   9690  N  N   . SER E 1 219 ? 52.290  93.750  68.803  1.00 21.75  ? 219 SER E N   1 
ATOM   9691  C  CA  . SER E 1 219 ? 52.859  92.400  68.775  1.00 22.38  ? 219 SER E CA  1 
ATOM   9692  C  C   . SER E 1 219 ? 52.928  91.821  70.187  1.00 23.43  ? 219 SER E C   1 
ATOM   9693  O  O   . SER E 1 219 ? 53.591  92.391  71.066  1.00 23.50  ? 219 SER E O   1 
ATOM   9694  C  CB  . SER E 1 219 ? 54.255  92.408  68.143  1.00 19.21  ? 219 SER E CB  1 
ATOM   9695  O  OG  . SER E 1 219 ? 55.029  91.312  68.579  1.00 18.93  ? 219 SER E OG  1 
ATOM   9696  N  N   . THR E 1 220 ? 52.281  90.667  70.390  1.00 20.23  ? 220 THR E N   1 
ATOM   9697  C  CA  . THR E 1 220 ? 52.373  89.986  71.682  1.00 20.29  ? 220 THR E CA  1 
ATOM   9698  C  C   . THR E 1 220 ? 53.777  89.449  71.914  1.00 22.65  ? 220 THR E C   1 
ATOM   9699  O  O   . THR E 1 220 ? 54.298  89.497  73.038  1.00 20.52  ? 220 THR E O   1 
ATOM   9700  C  CB  . THR E 1 220 ? 51.378  88.830  71.745  1.00 22.76  ? 220 THR E CB  1 
ATOM   9701  O  OG1 . THR E 1 220 ? 50.130  89.231  71.172  1.00 24.57  ? 220 THR E OG1 1 
ATOM   9702  C  CG2 . THR E 1 220 ? 51.169  88.380  73.192  1.00 25.11  ? 220 THR E CG2 1 
ATOM   9703  N  N   . VAL E 1 221 ? 54.385  88.899  70.862  1.00 20.53  ? 221 VAL E N   1 
ATOM   9704  C  CA  . VAL E 1 221 ? 55.717  88.328  70.991  1.00 20.72  ? 221 VAL E CA  1 
ATOM   9705  C  C   . VAL E 1 221 ? 56.689  89.391  71.480  1.00 19.40  ? 221 VAL E C   1 
ATOM   9706  O  O   . VAL E 1 221 ? 57.416  89.177  72.453  1.00 20.98  ? 221 VAL E O   1 
ATOM   9707  C  CB  . VAL E 1 221 ? 56.163  87.701  69.655  1.00 21.04  ? 221 VAL E CB  1 
ATOM   9708  C  CG1 . VAL E 1 221 ? 57.683  87.477  69.648  1.00 16.16  ? 221 VAL E CG1 1 
ATOM   9709  C  CG2 . VAL E 1 221 ? 55.390  86.378  69.396  1.00 19.49  ? 221 VAL E CG2 1 
ATOM   9710  N  N   . ASP E 1 222 ? 56.702  90.563  70.822  1.00 19.12  ? 222 ASP E N   1 
ATOM   9711  C  CA  . ASP E 1 222 ? 57.594  91.649  71.250  1.00 23.61  ? 222 ASP E CA  1 
ATOM   9712  C  C   . ASP E 1 222 ? 57.249  92.139  72.655  1.00 19.18  ? 222 ASP E C   1 
ATOM   9713  O  O   . ASP E 1 222 ? 58.143  92.392  73.466  1.00 18.95  ? 222 ASP E O   1 
ATOM   9714  C  CB  . ASP E 1 222 ? 57.531  92.835  70.280  1.00 17.99  ? 222 ASP E CB  1 
ATOM   9715  C  CG  . ASP E 1 222 ? 58.163  92.545  68.934  1.00 21.90  ? 222 ASP E CG  1 
ATOM   9716  O  OD1 . ASP E 1 222 ? 59.104  91.718  68.844  1.00 25.01  ? 222 ASP E OD1 1 
ATOM   9717  O  OD2 . ASP E 1 222 ? 57.698  93.156  67.954  1.00 25.58  ? 222 ASP E OD2 1 
ATOM   9718  N  N   . ALA E 1 223 ? 55.961  92.286  72.953  1.00 19.81  ? 223 ALA E N   1 
ATOM   9719  C  CA  . ALA E 1 223 ? 55.569  92.847  74.247  1.00 20.78  ? 223 ALA E CA  1 
ATOM   9720  C  C   . ALA E 1 223 ? 56.067  91.986  75.406  1.00 18.60  ? 223 ALA E C   1 
ATOM   9721  O  O   . ALA E 1 223 ? 56.645  92.505  76.364  1.00 24.45  ? 223 ALA E O   1 
ATOM   9722  C  CB  . ALA E 1 223 ? 54.054  93.030  74.311  1.00 18.28  ? 223 ALA E CB  1 
ATOM   9723  N  N   . VAL E 1 224 ? 55.868  90.664  75.344  1.00 21.58  ? 224 VAL E N   1 
ATOM   9724  C  CA  . VAL E 1 224 ? 56.270  89.869  76.507  1.00 17.64  ? 224 VAL E CA  1 
ATOM   9725  C  C   . VAL E 1 224 ? 57.789  89.778  76.572  1.00 24.86  ? 224 VAL E C   1 
ATOM   9726  O  O   . VAL E 1 224 ? 58.379  89.716  77.663  1.00 22.04  ? 224 VAL E O   1 
ATOM   9727  C  CB  . VAL E 1 224 ? 55.625  88.473  76.488  1.00 20.11  ? 224 VAL E CB  1 
ATOM   9728  C  CG1 . VAL E 1 224 ? 54.096  88.580  76.495  1.00 19.98  ? 224 VAL E CG1 1 
ATOM   9729  C  CG2 . VAL E 1 224 ? 56.137  87.608  75.295  1.00 23.48  ? 224 VAL E CG2 1 
ATOM   9730  N  N   . ARG E 1 225 ? 58.451  89.787  75.411  1.00 18.77  ? 225 ARG E N   1 
ATOM   9731  C  CA  . ARG E 1 225 ? 59.903  89.773  75.421  1.00 19.04  ? 225 ARG E CA  1 
ATOM   9732  C  C   . ARG E 1 225 ? 60.440  91.092  75.943  1.00 20.14  ? 225 ARG E C   1 
ATOM   9733  O  O   . ARG E 1 225 ? 61.443  91.123  76.660  1.00 22.03  ? 225 ARG E O   1 
ATOM   9734  C  CB  . ARG E 1 225 ? 60.428  89.468  74.014  1.00 19.27  ? 225 ARG E CB  1 
ATOM   9735  C  CG  . ARG E 1 225 ? 60.234  88.016  73.623  1.00 22.26  ? 225 ARG E CG  1 
ATOM   9736  C  CD  . ARG E 1 225 ? 60.625  87.752  72.171  1.00 24.47  ? 225 ARG E CD  1 
ATOM   9737  N  NE  . ARG E 1 225 ? 60.303  86.390  71.767  1.00 24.07  ? 225 ARG E NE  1 
ATOM   9738  C  CZ  . ARG E 1 225 ? 60.692  85.861  70.616  1.00 23.15  ? 225 ARG E CZ  1 
ATOM   9739  N  NH1 . ARG E 1 225 ? 61.411  86.561  69.749  1.00 21.02  ? 225 ARG E NH1 1 
ATOM   9740  N  NH2 . ARG E 1 225 ? 60.348  84.609  70.326  1.00 20.84  ? 225 ARG E NH2 1 
ATOM   9741  N  N   . SER E 1 226 ? 59.756  92.188  75.623  1.00 19.36  ? 226 SER E N   1 
ATOM   9742  C  CA  . SER E 1 226 ? 60.141  93.482  76.168  1.00 20.91  ? 226 SER E CA  1 
ATOM   9743  C  C   . SER E 1 226 ? 59.958  93.516  77.682  1.00 22.80  ? 226 SER E C   1 
ATOM   9744  O  O   . SER E 1 226 ? 60.751  94.143  78.394  1.00 21.74  ? 226 SER E O   1 
ATOM   9745  C  CB  . SER E 1 226 ? 59.333  94.593  75.498  1.00 22.19  ? 226 SER E CB  1 
ATOM   9746  O  OG  . SER E 1 226 ? 59.808  94.836  74.186  1.00 22.02  ? 226 SER E OG  1 
ATOM   9747  N  N   . VAL E 1 227 ? 58.925  92.847  78.196  1.00 21.22  ? 227 VAL E N   1 
ATOM   9748  C  CA  . VAL E 1 227 ? 58.769  92.836  79.642  1.00 22.79  ? 227 VAL E CA  1 
ATOM   9749  C  C   . VAL E 1 227 ? 59.955  92.120  80.275  1.00 25.57  ? 227 VAL E C   1 
ATOM   9750  O  O   . VAL E 1 227 ? 60.547  92.607  81.246  1.00 27.44  ? 227 VAL E O   1 
ATOM   9751  C  CB  . VAL E 1 227 ? 57.421  92.210  80.046  1.00 22.96  ? 227 VAL E CB  1 
ATOM   9752  C  CG1 . VAL E 1 227 ? 57.453  91.787  81.520  1.00 22.48  ? 227 VAL E CG1 1 
ATOM   9753  C  CG2 . VAL E 1 227 ? 56.290  93.195  79.773  1.00 21.02  ? 227 VAL E CG2 1 
ATOM   9754  N  N   . ARG E 1 228 ? 60.369  90.991  79.691  1.00 25.03  ? 228 ARG E N   1 
ATOM   9755  C  CA  . ARG E 1 228 ? 61.495  90.263  80.260  1.00 23.48  ? 228 ARG E CA  1 
ATOM   9756  C  C   . ARG E 1 228 ? 62.794  91.037  80.111  1.00 25.51  ? 228 ARG E C   1 
ATOM   9757  O  O   . ARG E 1 228 ? 63.655  90.961  80.990  1.00 24.56  ? 228 ARG E O   1 
ATOM   9758  C  CB  . ARG E 1 228 ? 61.599  88.881  79.628  1.00 24.80  ? 228 ARG E CB  1 
ATOM   9759  C  CG  . ARG E 1 228 ? 60.430  88.006  80.048  1.00 25.76  ? 228 ARG E CG  1 
ATOM   9760  C  CD  . ARG E 1 228 ? 60.712  86.530  79.837  1.00 26.41  ? 228 ARG E CD  1 
ATOM   9761  N  NE  . ARG E 1 228 ? 59.663  85.749  80.471  1.00 28.61  ? 228 ARG E NE  1 
ATOM   9762  C  CZ  . ARG E 1 228 ? 59.634  84.428  80.551  1.00 30.06  ? 228 ARG E CZ  1 
ATOM   9763  N  NH1 . ARG E 1 228 ? 60.600  83.682  80.039  1.00 29.67  ? 228 ARG E NH1 1 
ATOM   9764  N  NH2 . ARG E 1 228 ? 58.610  83.842  81.162  1.00 27.27  ? 228 ARG E NH2 1 
ATOM   9765  N  N   . LYS E 1 229 ? 62.958  91.774  79.008  1.00 23.23  ? 229 LYS E N   1 
ATOM   9766  C  CA  . LYS E 1 229 ? 64.056  92.724  78.925  1.00 23.31  ? 229 LYS E CA  1 
ATOM   9767  C  C   . LYS E 1 229 ? 64.061  93.651  80.135  1.00 25.99  ? 229 LYS E C   1 
ATOM   9768  O  O   . LYS E 1 229 ? 65.117  93.920  80.721  1.00 23.60  ? 229 LYS E O   1 
ATOM   9769  C  CB  . LYS E 1 229 ? 63.960  93.547  77.639  1.00 22.15  ? 229 LYS E CB  1 
ATOM   9770  C  CG  . LYS E 1 229 ? 65.126  94.536  77.455  1.00 22.09  ? 229 LYS E CG  1 
ATOM   9771  C  CD  . LYS E 1 229 ? 65.013  95.233  76.115  1.00 24.14  ? 229 LYS E CD  1 
ATOM   9772  C  CE  . LYS E 1 229 ? 66.156  96.196  75.839  1.00 25.96  ? 229 LYS E CE  1 
ATOM   9773  N  NZ  . LYS E 1 229 ? 65.932  96.825  74.510  1.00 27.94  ? 229 LYS E NZ  1 
ATOM   9774  N  N   . LEU E 1 230 ? 62.886  94.165  80.511  1.00 25.69  ? 230 LEU E N   1 
ATOM   9775  C  CA  . LEU E 1 230 ? 62.829  95.082  81.641  1.00 28.03  ? 230 LEU E CA  1 
ATOM   9776  C  C   . LEU E 1 230 ? 63.138  94.355  82.944  1.00 25.32  ? 230 LEU E C   1 
ATOM   9777  O  O   . LEU E 1 230 ? 63.813  94.913  83.812  1.00 26.88  ? 230 LEU E O   1 
ATOM   9778  C  CB  . LEU E 1 230 ? 61.462  95.773  81.705  1.00 25.57  ? 230 LEU E CB  1 
ATOM   9779  C  CG  . LEU E 1 230 ? 61.144  96.823  80.630  1.00 24.38  ? 230 LEU E CG  1 
ATOM   9780  C  CD1 . LEU E 1 230 ? 59.968  97.689  81.062  1.00 26.36  ? 230 LEU E CD1 1 
ATOM   9781  C  CD2 . LEU E 1 230 ? 62.337  97.704  80.283  1.00 19.77  ? 230 LEU E CD2 1 
ATOM   9782  N  N   . HIS E 1 231 ? 62.672  93.106  83.088  1.00 24.11  ? 231 HIS E N   1 
ATOM   9783  C  CA  . HIS E 1 231 ? 63.057  92.288  84.239  1.00 27.69  ? 231 HIS E CA  1 
ATOM   9784  C  C   . HIS E 1 231 ? 64.571  92.274  84.404  1.00 28.53  ? 231 HIS E C   1 
ATOM   9785  O  O   . HIS E 1 231 ? 65.092  92.573  85.486  1.00 29.85  ? 231 HIS E O   1 
ATOM   9786  C  CB  . HIS E 1 231 ? 62.543  90.849  84.094  1.00 25.82  ? 231 HIS E CB  1 
ATOM   9787  C  CG  . HIS E 1 231 ? 61.053  90.713  84.163  1.00 25.65  ? 231 HIS E CG  1 
ATOM   9788  N  ND1 . HIS E 1 231 ? 60.408  89.518  83.925  1.00 27.56  ? 231 HIS E ND1 1 
ATOM   9789  C  CD2 . HIS E 1 231 ? 60.084  91.610  84.461  1.00 26.25  ? 231 HIS E CD2 1 
ATOM   9790  C  CE1 . HIS E 1 231 ? 59.105  89.685  84.060  1.00 28.86  ? 231 HIS E CE1 1 
ATOM   9791  N  NE2 . HIS E 1 231 ? 58.879  90.948  84.379  1.00 27.71  ? 231 HIS E NE2 1 
ATOM   9792  N  N   . ALA E 1 232 ? 65.299  91.960  83.326  1.00 24.19  ? 232 ALA E N   1 
ATOM   9793  C  CA  . ALA E 1 232 ? 66.758  91.904  83.424  1.00 25.13  ? 232 ALA E CA  1 
ATOM   9794  C  C   . ALA E 1 232 ? 67.343  93.265  83.788  1.00 24.51  ? 232 ALA E C   1 
ATOM   9795  O  O   . ALA E 1 232 ? 68.271  93.353  84.600  1.00 27.07  ? 232 ALA E O   1 
ATOM   9796  C  CB  . ALA E 1 232 ? 67.359  91.382  82.115  1.00 22.90  ? 232 ALA E CB  1 
ATOM   9797  N  N   . LEU E 1 233 ? 66.825  94.338  83.195  1.00 23.03  ? 233 LEU E N   1 
ATOM   9798  C  CA  . LEU E 1 233 ? 67.340  95.664  83.522  1.00 26.74  ? 233 LEU E CA  1 
ATOM   9799  C  C   . LEU E 1 233 ? 67.073  96.010  84.985  1.00 27.98  ? 233 LEU E C   1 
ATOM   9800  O  O   . LEU E 1 233 ? 67.962  96.498  85.695  1.00 25.66  ? 233 LEU E O   1 
ATOM   9801  C  CB  . LEU E 1 233 ? 66.722  96.714  82.600  1.00 24.81  ? 233 LEU E CB  1 
ATOM   9802  C  CG  . LEU E 1 233 ? 67.181  98.161  82.830  1.00 24.37  ? 233 LEU E CG  1 
ATOM   9803  C  CD1 . LEU E 1 233 ? 68.684  98.232  82.749  1.00 26.63  ? 233 LEU E CD1 1 
ATOM   9804  C  CD2 . LEU E 1 233 ? 66.561  99.121  81.807  1.00 22.00  ? 233 LEU E CD2 1 
ATOM   9805  N  N   . ALA E 1 234 ? 65.844  95.772  85.443  1.00 26.19  ? 234 ALA E N   1 
ATOM   9806  C  CA  . ALA E 1 234 ? 65.501  96.036  86.835  1.00 29.46  ? 234 ALA E CA  1 
ATOM   9807  C  C   . ALA E 1 234 ? 66.397  95.247  87.787  1.00 31.17  ? 234 ALA E C   1 
ATOM   9808  O  O   . ALA E 1 234 ? 66.961  95.810  88.731  1.00 30.30  ? 234 ALA E O   1 
ATOM   9809  C  CB  . ALA E 1 234 ? 64.028  95.709  87.084  1.00 28.17  ? 234 ALA E CB  1 
ATOM   9810  N  N   . GLU E 1 235 ? 66.554  93.942  87.544  1.00 30.24  ? 235 GLU E N   1 
ATOM   9811  C  CA  . GLU E 1 235 ? 67.389  93.131  88.424  1.00 29.16  ? 235 GLU E CA  1 
ATOM   9812  C  C   . GLU E 1 235 ? 68.845  93.587  88.392  1.00 29.61  ? 235 GLU E C   1 
ATOM   9813  O  O   . GLU E 1 235 ? 69.533  93.545  89.415  1.00 28.82  ? 235 GLU E O   1 
ATOM   9814  C  CB  . GLU E 1 235 ? 67.269  91.653  88.050  1.00 31.84  ? 235 GLU E CB  1 
ATOM   9815  C  CG  . GLU E 1 235 ? 67.927  90.685  89.051  1.00 32.21  ? 235 GLU E CG  1 
ATOM   9816  C  CD  . GLU E 1 235 ? 69.442  90.528  88.826  1.00 34.75  ? 235 GLU E CD  1 
ATOM   9817  O  OE1 . GLU E 1 235 ? 69.927  90.948  87.761  1.00 32.60  ? 235 GLU E OE1 1 
ATOM   9818  O  OE2 . GLU E 1 235 ? 70.151  90.008  89.716  1.00 34.39  ? 235 GLU E OE2 1 
ATOM   9819  N  N   . LYS E 1 236 ? 69.333  94.022  87.228  1.00 29.16  ? 236 LYS E N   1 
ATOM   9820  C  CA  . LYS E 1 236 ? 70.728  94.446  87.107  1.00 26.41  ? 236 LYS E CA  1 
ATOM   9821  C  C   . LYS E 1 236 ? 70.994  95.742  87.872  1.00 35.22  ? 236 LYS E C   1 
ATOM   9822  O  O   . LYS E 1 236 ? 72.052  95.899  88.500  1.00 33.73  ? 236 LYS E O   1 
ATOM   9823  C  CB  . LYS E 1 236 ? 71.099  94.630  85.634  1.00 27.49  ? 236 LYS E CB  1 
ATOM   9824  C  CG  . LYS E 1 236 ? 72.375  95.432  85.382  1.00 27.47  ? 236 LYS E CG  1 
ATOM   9825  C  CD  . LYS E 1 236 ? 72.659  95.540  83.867  1.00 32.47  ? 236 LYS E CD  1 
ATOM   9826  C  CE  . LYS E 1 236 ? 73.762  96.526  83.555  1.00 31.09  ? 236 LYS E CE  1 
ATOM   9827  N  NZ  . LYS E 1 236 ? 74.100  96.560  82.085  1.00 32.43  ? 236 LYS E NZ  1 
ATOM   9828  N  N   . THR E 1 237 ? 70.053  96.687  87.820  1.00 32.11  ? 237 THR E N   1 
ATOM   9829  C  CA  . THR E 1 237 ? 70.275  98.025  88.353  1.00 33.51  ? 237 THR E CA  1 
ATOM   9830  C  C   . THR E 1 237 ? 69.652  98.249  89.727  1.00 33.54  ? 237 THR E C   1 
ATOM   9831  O  O   . THR E 1 237 ? 70.009  99.226  90.394  1.00 34.53  ? 237 THR E O   1 
ATOM   9832  C  CB  . THR E 1 237 ? 69.713  99.087  87.396  1.00 30.25  ? 237 THR E CB  1 
ATOM   9833  O  OG1 . THR E 1 237 ? 68.284  98.966  87.349  1.00 29.83  ? 237 THR E OG1 1 
ATOM   9834  C  CG2 . THR E 1 237 ? 70.300  98.937  85.978  1.00 32.18  ? 237 THR E CG2 1 
ATOM   9835  N  N   . GLY E 1 238 ? 68.728  97.395  90.160  1.00 29.47  ? 238 GLY E N   1 
ATOM   9836  C  CA  . GLY E 1 238 ? 67.966  97.734  91.346  1.00 30.61  ? 238 GLY E CA  1 
ATOM   9837  C  C   . GLY E 1 238 ? 67.019  98.898  91.158  1.00 36.20  ? 238 GLY E C   1 
ATOM   9838  O  O   . GLY E 1 238 ? 66.671  99.575  92.130  1.00 36.37  ? 238 GLY E O   1 
ATOM   9839  N  N   . ALA E 1 239 ? 66.587  99.153  89.926  1.00 31.08  ? 239 ALA E N   1 
ATOM   9840  C  CA  . ALA E 1 239 ? 65.796  100.335 89.641  1.00 32.73  ? 239 ALA E CA  1 
ATOM   9841  C  C   . ALA E 1 239 ? 64.445  100.270 90.341  1.00 31.99  ? 239 ALA E C   1 
ATOM   9842  O  O   . ALA E 1 239 ? 63.888  99.193  90.576  1.00 31.85  ? 239 ALA E O   1 
ATOM   9843  C  CB  . ALA E 1 239 ? 65.586  100.488 88.131  1.00 34.01  ? 239 ALA E CB  1 
ATOM   9844  N  N   . LEU E 1 240 ? 63.933  101.448 90.682  1.00 32.04  ? 240 LEU E N   1 
ATOM   9845  C  CA  . LEU E 1 240 ? 62.540  101.611 91.077  1.00 30.52  ? 240 LEU E CA  1 
ATOM   9846  C  C   . LEU E 1 240 ? 61.658  101.549 89.838  1.00 28.75  ? 240 LEU E C   1 
ATOM   9847  O  O   . LEU E 1 240 ? 61.841  102.346 88.908  1.00 30.40  ? 240 LEU E O   1 
ATOM   9848  C  CB  . LEU E 1 240 ? 62.360  102.949 91.783  1.00 30.39  ? 240 LEU E CB  1 
ATOM   9849  C  CG  . LEU E 1 240 ? 60.914  103.404 91.997  1.00 35.39  ? 240 LEU E CG  1 
ATOM   9850  C  CD1 . LEU E 1 240 ? 60.258  102.546 93.048  1.00 34.99  ? 240 LEU E CD1 1 
ATOM   9851  C  CD2 . LEU E 1 240 ? 60.866  104.878 92.384  1.00 36.41  ? 240 LEU E CD2 1 
ATOM   9852  N  N   . VAL E 1 241 ? 60.696  100.628 89.819  1.00 28.26  ? 241 VAL E N   1 
ATOM   9853  C  CA  . VAL E 1 241 ? 59.920  100.353 88.614  1.00 32.01  ? 241 VAL E CA  1 
ATOM   9854  C  C   . VAL E 1 241 ? 58.581  101.078 88.681  1.00 34.38  ? 241 VAL E C   1 
ATOM   9855  O  O   . VAL E 1 241 ? 57.765  100.825 89.575  1.00 31.54  ? 241 VAL E O   1 
ATOM   9856  C  CB  . VAL E 1 241 ? 59.731  98.844  88.401  1.00 32.47  ? 241 VAL E CB  1 
ATOM   9857  C  CG1 . VAL E 1 241 ? 58.878  98.599  87.169  1.00 29.90  ? 241 VAL E CG1 1 
ATOM   9858  C  CG2 . VAL E 1 241 ? 61.099  98.172  88.236  1.00 26.28  ? 241 VAL E CG2 1 
ATOM   9859  N  N   . VAL E 1 242 ? 58.346  101.962 87.716  1.00 32.60  ? 242 VAL E N   1 
ATOM   9860  C  CA  . VAL E 1 242 ? 57.131  102.763 87.626  1.00 29.46  ? 242 VAL E CA  1 
ATOM   9861  C  C   . VAL E 1 242 ? 56.306  102.219 86.463  1.00 34.08  ? 242 VAL E C   1 
ATOM   9862  O  O   . VAL E 1 242 ? 56.692  102.363 85.296  1.00 31.34  ? 242 VAL E O   1 
ATOM   9863  C  CB  . VAL E 1 242 ? 57.454  104.252 87.428  1.00 33.82  ? 242 VAL E CB  1 
ATOM   9864  C  CG1 . VAL E 1 242 ? 56.176  105.101 87.462  1.00 33.47  ? 242 VAL E CG1 1 
ATOM   9865  C  CG2 . VAL E 1 242 ? 58.484  104.727 88.451  1.00 32.59  ? 242 VAL E CG2 1 
ATOM   9866  N  N   . TYR E 1 243 ? 55.171  101.596 86.774  1.00 34.55  ? 243 TYR E N   1 
ATOM   9867  C  CA  . TYR E 1 243 ? 54.284  101.059 85.757  1.00 32.95  ? 243 TYR E CA  1 
ATOM   9868  C  C   . TYR E 1 243 ? 53.555  102.179 85.019  1.00 33.87  ? 243 TYR E C   1 
ATOM   9869  O  O   . TYR E 1 243 ? 53.473  103.318 85.476  1.00 34.07  ? 243 TYR E O   1 
ATOM   9870  C  CB  . TYR E 1 243 ? 53.294  100.086 86.394  1.00 33.77  ? 243 TYR E CB  1 
ATOM   9871  C  CG  . TYR E 1 243 ? 54.018  99.127  87.293  1.00 34.94  ? 243 TYR E CG  1 
ATOM   9872  C  CD1 . TYR E 1 243 ? 54.689  98.029  86.762  1.00 33.25  ? 243 TYR E CD1 1 
ATOM   9873  C  CD2 . TYR E 1 243 ? 54.102  99.351  88.657  1.00 37.20  ? 243 TYR E CD2 1 
ATOM   9874  C  CE1 . TYR E 1 243 ? 55.386  97.161  87.564  1.00 36.86  ? 243 TYR E CE1 1 
ATOM   9875  C  CE2 . TYR E 1 243 ? 54.807  98.492  89.473  1.00 38.07  ? 243 TYR E CE2 1 
ATOM   9876  C  CZ  . TYR E 1 243 ? 55.443  97.394  88.915  1.00 37.88  ? 243 TYR E CZ  1 
ATOM   9877  O  OH  . TYR E 1 243 ? 56.140  96.529  89.715  1.00 37.27  ? 243 TYR E OH  1 
ATOM   9878  N  N   . GLY E 1 244 ? 53.024  101.838 83.851  1.00 32.83  ? 244 GLY E N   1 
ATOM   9879  C  CA  . GLY E 1 244 ? 52.453  102.837 82.970  1.00 33.65  ? 244 GLY E CA  1 
ATOM   9880  C  C   . GLY E 1 244 ? 51.103  103.410 83.352  1.00 39.21  ? 244 GLY E C   1 
ATOM   9881  O  O   . GLY E 1 244 ? 50.920  104.631 83.305  1.00 37.83  ? 244 GLY E O   1 
ATOM   9882  N  N   . HIS E 1 245 ? 50.141  102.539 83.703  1.00 37.91  ? 245 HIS E N   1 
ATOM   9883  C  CA  . HIS E 1 245 ? 48.740  102.884 83.967  1.00 39.72  ? 245 HIS E CA  1 
ATOM   9884  C  C   . HIS E 1 245 ? 48.223  101.945 85.065  1.00 41.85  ? 245 HIS E C   1 
ATOM   9885  O  O   . HIS E 1 245 ? 47.381  101.075 84.858  1.00 41.45  ? 245 HIS E O   1 
ATOM   9886  C  CB  . HIS E 1 245 ? 47.875  102.742 82.712  1.00 40.25  ? 245 HIS E CB  1 
ATOM   9887  C  CG  . HIS E 1 245 ? 48.263  103.641 81.579  1.00 43.58  ? 245 HIS E CG  1 
ATOM   9888  N  ND1 . HIS E 1 245 ? 48.142  105.014 81.636  1.00 40.20  ? 245 HIS E ND1 1 
ATOM   9889  C  CD2 . HIS E 1 245 ? 48.750  103.357 80.345  1.00 41.55  ? 245 HIS E CD2 1 
ATOM   9890  C  CE1 . HIS E 1 245 ? 48.537  105.537 80.488  1.00 41.12  ? 245 HIS E CE1 1 
ATOM   9891  N  NE2 . HIS E 1 245 ? 48.915  104.553 79.689  1.00 42.00  ? 245 HIS E NE2 1 
ATOM   9892  N  N   . ASP E 1 246 ? 48.735  102.080 86.281  1.00 38.98  ? 246 ASP E N   1 
ATOM   9893  C  CA  . ASP E 1 246 ? 48.367  101.156 87.356  1.00 42.41  ? 246 ASP E CA  1 
ATOM   9894  C  C   . ASP E 1 246 ? 47.660  101.909 88.478  1.00 44.53  ? 246 ASP E C   1 
ATOM   9895  O  O   . ASP E 1 246 ? 48.321  102.560 89.309  1.00 44.23  ? 246 ASP E O   1 
ATOM   9896  C  CB  . ASP E 1 246 ? 49.595  100.418 87.880  1.00 40.00  ? 246 ASP E CB  1 
ATOM   9897  C  CG  . ASP E 1 246 ? 49.236  99.282  88.821  1.00 43.09  ? 246 ASP E CG  1 
ATOM   9898  O  OD1 . ASP E 1 246 ? 48.257  99.399  89.590  1.00 46.33  ? 246 ASP E OD1 1 
ATOM   9899  O  OD2 . ASP E 1 246 ? 49.939  98.254  88.792  1.00 42.42  ? 246 ASP E OD2 1 
ATOM   9900  N  N   . PRO E 1 247 ? 46.330  101.822 88.558  1.00 45.64  ? 247 PRO E N   1 
ATOM   9901  C  CA  . PRO E 1 247 ? 45.589  102.629 89.547  1.00 45.36  ? 247 PRO E CA  1 
ATOM   9902  C  C   . PRO E 1 247 ? 45.979  102.337 90.985  1.00 47.92  ? 247 PRO E C   1 
ATOM   9903  O  O   . PRO E 1 247 ? 45.860  103.225 91.838  1.00 47.21  ? 247 PRO E O   1 
ATOM   9904  C  CB  . PRO E 1 247 ? 44.120  102.258 89.295  1.00 48.35  ? 247 PRO E CB  1 
ATOM   9905  C  CG  . PRO E 1 247 ? 44.083  101.417 88.070  1.00 49.86  ? 247 PRO E CG  1 
ATOM   9906  C  CD  . PRO E 1 247 ? 45.466  100.954 87.743  1.00 46.72  ? 247 PRO E CD  1 
ATOM   9907  N  N   . GLU E 1 248 ? 46.443  101.122 91.280  1.00 45.79  ? 248 GLU E N   1 
ATOM   9908  C  CA  . GLU E 1 248 ? 46.834  100.732 92.627  1.00 41.41  ? 248 GLU E CA  1 
ATOM   9909  C  C   . GLU E 1 248 ? 48.260  101.151 92.950  1.00 46.50  ? 248 GLU E C   1 
ATOM   9910  O  O   . GLU E 1 248 ? 48.527  101.647 94.050  1.00 48.26  ? 248 GLU E O   1 
ATOM   9911  C  CB  . GLU E 1 248 ? 46.700  99.221  92.785  1.00 45.52  ? 248 GLU E CB  1 
ATOM   9912  C  CG  . GLU E 1 248 ? 45.491  98.662  92.066  1.00 51.35  ? 248 GLU E CG  1 
ATOM   9913  C  CD  . GLU E 1 248 ? 45.084  97.288  92.563  1.00 66.08  ? 248 GLU E CD  1 
ATOM   9914  O  OE1 . GLU E 1 248 ? 45.669  96.278  92.097  1.00 64.51  ? 248 GLU E OE1 1 
ATOM   9915  O  OE2 . GLU E 1 248 ? 44.163  97.214  93.403  1.00 70.97  ? 248 GLU E OE2 1 
ATOM   9916  N  N   . ALA E 1 249 ? 49.190  100.960 92.012  1.00 44.08  ? 249 ALA E N   1 
ATOM   9917  C  CA  . ALA E 1 249 ? 50.584  101.252 92.306  1.00 43.38  ? 249 ALA E CA  1 
ATOM   9918  C  C   . ALA E 1 249 ? 50.887  102.739 92.196  1.00 43.53  ? 249 ALA E C   1 
ATOM   9919  O  O   . ALA E 1 249 ? 51.764  103.239 92.909  1.00 46.33  ? 249 ALA E O   1 
ATOM   9920  C  CB  . ALA E 1 249 ? 51.493  100.443 91.379  1.00 40.97  ? 249 ALA E CB  1 
ATOM   9921  N  N   . TRP E 1 250 ? 50.168  103.457 91.332  1.00 43.26  ? 250 TRP E N   1 
ATOM   9922  C  CA  . TRP E 1 250 ? 50.406  104.887 91.125  1.00 43.49  ? 250 TRP E CA  1 
ATOM   9923  C  C   . TRP E 1 250 ? 50.366  105.704 92.415  1.00 44.98  ? 250 TRP E C   1 
ATOM   9924  O  O   . TRP E 1 250 ? 51.322  106.450 92.668  1.00 45.73  ? 250 TRP E O   1 
ATOM   9925  C  CB  . TRP E 1 250 ? 49.404  105.408 90.080  1.00 42.07  ? 250 TRP E CB  1 
ATOM   9926  C  CG  . TRP E 1 250 ? 49.610  106.832 89.611  1.00 39.74  ? 250 TRP E CG  1 
ATOM   9927  C  CD1 . TRP E 1 250 ? 48.717  107.862 89.706  1.00 37.02  ? 250 TRP E CD1 1 
ATOM   9928  C  CD2 . TRP E 1 250 ? 50.759  107.367 88.940  1.00 41.83  ? 250 TRP E CD2 1 
ATOM   9929  N  NE1 . TRP E 1 250 ? 49.244  109.007 89.162  1.00 39.95  ? 250 TRP E NE1 1 
ATOM   9930  C  CE2 . TRP E 1 250 ? 50.498  108.730 88.684  1.00 38.44  ? 250 TRP E CE2 1 
ATOM   9931  C  CE3 . TRP E 1 250 ? 51.985  106.832 88.543  1.00 44.05  ? 250 TRP E CE3 1 
ATOM   9932  C  CZ2 . TRP E 1 250 ? 51.413  109.556 88.044  1.00 38.95  ? 250 TRP E CZ2 1 
ATOM   9933  C  CZ3 . TRP E 1 250 ? 52.896  107.660 87.912  1.00 42.54  ? 250 TRP E CZ3 1 
ATOM   9934  C  CH2 . TRP E 1 250 ? 52.608  109.005 87.674  1.00 41.37  ? 250 TRP E CH2 1 
ATOM   9935  N  N   . PRO E 1 251 ? 49.338  105.606 93.269  1.00 50.84  ? 251 PRO E N   1 
ATOM   9936  C  CA  . PRO E 1 251 ? 49.340  106.403 94.517  1.00 47.68  ? 251 PRO E CA  1 
ATOM   9937  C  C   . PRO E 1 251 ? 50.553  106.179 95.410  1.00 44.88  ? 251 PRO E C   1 
ATOM   9938  O  O   . PRO E 1 251 ? 50.852  107.037 96.249  1.00 42.15  ? 251 PRO E O   1 
ATOM   9939  C  CB  . PRO E 1 251 ? 48.053  105.949 95.224  1.00 45.51  ? 251 PRO E CB  1 
ATOM   9940  C  CG  . PRO E 1 251 ? 47.173  105.445 94.129  1.00 50.23  ? 251 PRO E CG  1 
ATOM   9941  C  CD  . PRO E 1 251 ? 48.096  104.823 93.120  1.00 45.49  ? 251 PRO E CD  1 
ATOM   9942  N  N   . THR E 1 252 ? 51.249  105.054 95.269  1.00 48.47  ? 252 THR E N   1 
ATOM   9943  C  CA  . THR E 1 252 ? 52.386  104.723 96.122  1.00 48.18  ? 252 THR E CA  1 
ATOM   9944  C  C   . THR E 1 252 ? 53.679  105.409 95.697  1.00 51.14  ? 252 THR E C   1 
ATOM   9945  O  O   . THR E 1 252 ? 54.700  105.237 96.372  1.00 50.92  ? 252 THR E O   1 
ATOM   9946  C  CB  . THR E 1 252 ? 52.599  103.212 96.141  1.00 50.62  ? 252 THR E CB  1 
ATOM   9947  O  OG1 . THR E 1 252 ? 53.341  102.818 94.975  1.00 49.29  ? 252 THR E OG1 1 
ATOM   9948  C  CG2 . THR E 1 252 ? 51.244  102.489 96.157  1.00 47.24  ? 252 THR E CG2 1 
ATOM   9949  N  N   . PHE E 1 253 ? 53.670  106.174 94.611  1.00 47.47  ? 253 PHE E N   1 
ATOM   9950  C  CA  . PHE E 1 253 ? 54.853  106.899 94.180  1.00 49.59  ? 253 PHE E CA  1 
ATOM   9951  C  C   . PHE E 1 253 ? 54.746  108.361 94.600  1.00 48.39  ? 253 PHE E C   1 
ATOM   9952  O  O   . PHE E 1 253 ? 53.661  108.881 94.860  1.00 51.73  ? 253 PHE E O   1 
ATOM   9953  C  CB  . PHE E 1 253 ? 55.041  106.798 92.656  1.00 48.03  ? 253 PHE E CB  1 
ATOM   9954  C  CG  . PHE E 1 253 ? 55.308  105.393 92.156  1.00 48.43  ? 253 PHE E CG  1 
ATOM   9955  C  CD1 . PHE E 1 253 ? 56.530  104.780 92.386  1.00 44.01  ? 253 PHE E CD1 1 
ATOM   9956  C  CD2 . PHE E 1 253 ? 54.337  104.695 91.444  1.00 43.68  ? 253 PHE E CD2 1 
ATOM   9957  C  CE1 . PHE E 1 253 ? 56.772  103.489 91.936  1.00 42.07  ? 253 PHE E CE1 1 
ATOM   9958  C  CE2 . PHE E 1 253 ? 54.571  103.405 90.996  1.00 42.40  ? 253 PHE E CE2 1 
ATOM   9959  C  CZ  . PHE E 1 253 ? 55.788  102.799 91.245  1.00 40.27  ? 253 PHE E CZ  1 
ATOM   9960  N  N   . ARG E 1 254 ? 55.897  109.021 94.660  1.00 50.66  ? 254 ARG E N   1 
ATOM   9961  C  CA  . ARG E 1 254 ? 55.932  110.462 94.878  1.00 49.78  ? 254 ARG E CA  1 
ATOM   9962  C  C   . ARG E 1 254 ? 55.394  111.161 93.637  1.00 50.53  ? 254 ARG E C   1 
ATOM   9963  O  O   . ARG E 1 254 ? 56.014  111.116 92.569  1.00 48.09  ? 254 ARG E O   1 
ATOM   9964  C  CB  . ARG E 1 254 ? 57.356  110.913 95.196  1.00 50.23  ? 254 ARG E CB  1 
ATOM   9965  C  CG  . ARG E 1 254 ? 58.170  109.921 96.015  1.00 51.58  ? 254 ARG E CG  1 
ATOM   9966  C  CD  . ARG E 1 254 ? 59.617  110.401 96.268  1.00 53.80  ? 254 ARG E CD  1 
ATOM   9967  N  NE  . ARG E 1 254 ? 60.391  110.757 95.069  1.00 69.85  ? 254 ARG E NE  1 
ATOM   9968  C  CZ  . ARG E 1 254 ? 60.580  109.997 93.985  1.00 66.15  ? 254 ARG E CZ  1 
ATOM   9969  N  NH1 . ARG E 1 254 ? 60.041  108.794 93.868  1.00 61.87  ? 254 ARG E NH1 1 
ATOM   9970  N  NH2 . ARG E 1 254 ? 61.357  110.450 93.002  1.00 57.01  ? 254 ARG E NH2 1 
ATOM   9971  N  N   . LEU E 1 255 ? 54.248  111.812 93.767  1.00 47.65  ? 255 LEU E N   1 
ATOM   9972  C  CA  . LEU E 1 255 ? 53.571  112.348 92.600  1.00 48.12  ? 255 LEU E CA  1 
ATOM   9973  C  C   . LEU E 1 255 ? 53.604  113.870 92.524  1.00 44.70  ? 255 LEU E C   1 
ATOM   9974  O  O   . LEU E 1 255 ? 54.169  114.535 93.378  1.00 46.68  ? 255 LEU E O   1 
ATOM   9975  C  CB  . LEU E 1 255 ? 52.118  111.860 92.580  1.00 51.19  ? 255 LEU E CB  1 
ATOM   9976  C  CG  . LEU E 1 255 ? 51.901  110.341 92.592  1.00 47.73  ? 255 LEU E CG  1 
ATOM   9977  C  CD1 . LEU E 1 255 ? 50.437  110.031 92.341  1.00 40.49  ? 255 LEU E CD1 1 
ATOM   9978  C  CD2 . LEU E 1 255 ? 52.790  109.638 91.565  1.00 47.23  ? 255 LEU E CD2 1 
ATOM   9979  N  N   . ALA F 1 3   ? 63.937  71.506  19.600  1.00 47.12  ? 3   ALA F N   1 
ATOM   9980  C  CA  . ALA F 1 3   ? 63.616  70.950  20.922  1.00 47.64  ? 3   ALA F CA  1 
ATOM   9981  C  C   . ALA F 1 3   ? 64.854  70.862  21.830  1.00 48.76  ? 3   ALA F C   1 
ATOM   9982  O  O   . ALA F 1 3   ? 65.914  70.380  21.410  1.00 48.30  ? 3   ALA F O   1 
ATOM   9983  C  CB  . ALA F 1 3   ? 62.973  69.586  20.783  1.00 39.37  ? 3   ALA F CB  1 
ATOM   9984  N  N   . PRO F 1 4   ? 64.705  71.312  23.074  1.00 48.65  ? 4   PRO F N   1 
ATOM   9985  C  CA  . PRO F 1 4   ? 65.871  71.477  23.950  1.00 46.68  ? 4   PRO F CA  1 
ATOM   9986  C  C   . PRO F 1 4   ? 66.542  70.159  24.305  1.00 41.80  ? 4   PRO F C   1 
ATOM   9987  O  O   . PRO F 1 4   ? 65.895  69.116  24.423  1.00 41.00  ? 4   PRO F O   1 
ATOM   9988  C  CB  . PRO F 1 4   ? 65.277  72.144  25.199  1.00 43.86  ? 4   PRO F CB  1 
ATOM   9989  C  CG  . PRO F 1 4   ? 63.986  72.764  24.715  1.00 45.37  ? 4   PRO F CG  1 
ATOM   9990  C  CD  . PRO F 1 4   ? 63.467  71.768  23.728  1.00 41.14  ? 4   PRO F CD  1 
ATOM   9991  N  N   . ARG F 1 5   ? 67.863  70.224  24.503  1.00 38.65  ? 5   ARG F N   1 
ATOM   9992  C  CA  . ARG F 1 5   ? 68.636  69.076  24.965  1.00 43.38  ? 5   ARG F CA  1 
ATOM   9993  C  C   . ARG F 1 5   ? 69.664  69.502  26.008  1.00 40.56  ? 5   ARG F C   1 
ATOM   9994  O  O   . ARG F 1 5   ? 70.189  70.620  25.972  1.00 40.55  ? 5   ARG F O   1 
ATOM   9995  C  CB  . ARG F 1 5   ? 69.361  68.370  23.806  1.00 47.98  ? 5   ARG F CB  1 
ATOM   9996  C  CG  . ARG F 1 5   ? 68.436  67.781  22.774  1.00 50.89  ? 5   ARG F CG  1 
ATOM   9997  C  CD  . ARG F 1 5   ? 69.157  66.854  21.816  1.00 61.56  ? 5   ARG F CD  1 
ATOM   9998  N  NE  . ARG F 1 5   ? 69.620  67.553  20.623  1.00 60.21  ? 5   ARG F NE  1 
ATOM   9999  C  CZ  . ARG F 1 5   ? 69.681  67.009  19.413  1.00 66.96  ? 5   ARG F CZ  1 
ATOM   10000 N  NH1 . ARG F 1 5   ? 69.287  65.763  19.194  1.00 64.88  ? 5   ARG F NH1 1 
ATOM   10001 N  NH2 . ARG F 1 5   ? 70.150  67.734  18.401  1.00 67.36  ? 5   ARG F NH2 1 
ATOM   10002 N  N   . LEU F 1 6   ? 69.954  68.585  26.930  1.00 40.30  ? 6   LEU F N   1 
ATOM   10003 C  CA  . LEU F 1 6   ? 70.992  68.751  27.936  1.00 40.51  ? 6   LEU F CA  1 
ATOM   10004 C  C   . LEU F 1 6   ? 72.184  67.866  27.577  1.00 42.47  ? 6   LEU F C   1 
ATOM   10005 O  O   . LEU F 1 6   ? 72.049  66.642  27.483  1.00 42.33  ? 6   LEU F O   1 
ATOM   10006 C  CB  . LEU F 1 6   ? 70.460  68.392  29.324  1.00 37.60  ? 6   LEU F CB  1 
ATOM   10007 C  CG  . LEU F 1 6   ? 71.520  68.245  30.414  1.00 36.85  ? 6   LEU F CG  1 
ATOM   10008 C  CD1 . LEU F 1 6   ? 72.156  69.594  30.753  1.00 38.89  ? 6   LEU F CD1 1 
ATOM   10009 C  CD2 . LEU F 1 6   ? 70.957  67.566  31.643  1.00 37.99  ? 6   LEU F CD2 1 
ATOM   10010 N  N   . TYR F 1 7   ? 73.347  68.484  27.392  1.00 41.51  ? 7   TYR F N   1 
ATOM   10011 C  CA  . TYR F 1 7   ? 74.604  67.775  27.199  1.00 41.98  ? 7   TYR F CA  1 
ATOM   10012 C  C   . TYR F 1 7   ? 75.476  67.958  28.435  1.00 43.44  ? 7   TYR F C   1 
ATOM   10013 O  O   . TYR F 1 7   ? 75.743  69.096  28.844  1.00 38.83  ? 7   TYR F O   1 
ATOM   10014 C  CB  . TYR F 1 7   ? 75.351  68.289  25.967  1.00 44.40  ? 7   TYR F CB  1 
ATOM   10015 C  CG  . TYR F 1 7   ? 74.639  68.067  24.652  1.00 47.65  ? 7   TYR F CG  1 
ATOM   10016 C  CD1 . TYR F 1 7   ? 74.833  66.899  23.918  1.00 53.94  ? 7   TYR F CD1 1 
ATOM   10017 C  CD2 . TYR F 1 7   ? 73.782  69.027  24.140  1.00 44.57  ? 7   TYR F CD2 1 
ATOM   10018 C  CE1 . TYR F 1 7   ? 74.187  66.699  22.701  1.00 55.07  ? 7   TYR F CE1 1 
ATOM   10019 C  CE2 . TYR F 1 7   ? 73.128  68.841  22.936  1.00 53.22  ? 7   TYR F CE2 1 
ATOM   10020 C  CZ  . TYR F 1 7   ? 73.333  67.676  22.216  1.00 59.17  ? 7   TYR F CZ  1 
ATOM   10021 O  OH  . TYR F 1 7   ? 72.679  67.503  21.015  1.00 56.95  ? 7   TYR F OH  1 
ATOM   10022 N  N   . MET F 1 8   ? 75.944  66.841  29.005  1.00 39.05  ? 8   MET F N   1 
ATOM   10023 C  CA  . MET F 1 8   ? 76.810  66.851  30.179  1.00 38.58  ? 8   MET F CA  1 
ATOM   10024 C  C   . MET F 1 8   ? 78.266  66.660  29.760  1.00 43.15  ? 8   MET F C   1 
ATOM   10025 O  O   . MET F 1 8   ? 78.657  65.572  29.328  1.00 49.98  ? 8   MET F O   1 
ATOM   10026 C  CB  . MET F 1 8   ? 76.374  65.771  31.161  1.00 38.82  ? 8   MET F CB  1 
ATOM   10027 C  CG  . MET F 1 8   ? 75.047  66.089  31.826  1.00 40.22  ? 8   MET F CG  1 
ATOM   10028 S  SD  . MET F 1 8   ? 74.751  65.001  33.212  1.00 52.25  ? 8   MET F SD  1 
ATOM   10029 C  CE  . MET F 1 8   ? 72.966  65.040  33.312  1.00 42.12  ? 8   MET F CE  1 
ATOM   10030 N  N   . PHE F 1 9   ? 79.069  67.709  29.912  1.00 43.76  ? 9   PHE F N   1 
ATOM   10031 C  CA  . PHE F 1 9   ? 80.485  67.710  29.583  1.00 42.10  ? 9   PHE F CA  1 
ATOM   10032 C  C   . PHE F 1 9   ? 81.325  67.550  30.854  1.00 44.17  ? 9   PHE F C   1 
ATOM   10033 O  O   . PHE F 1 9   ? 80.809  67.192  31.923  1.00 44.64  ? 9   PHE F O   1 
ATOM   10034 C  CB  . PHE F 1 9   ? 80.857  69.003  28.866  1.00 43.85  ? 9   PHE F CB  1 
ATOM   10035 C  CG  . PHE F 1 9   ? 80.424  69.083  27.434  1.00 49.76  ? 9   PHE F CG  1 
ATOM   10036 C  CD1 . PHE F 1 9   ? 81.235  68.579  26.418  1.00 54.77  ? 9   PHE F CD1 1 
ATOM   10037 C  CD2 . PHE F 1 9   ? 79.245  69.726  27.088  1.00 45.82  ? 9   PHE F CD2 1 
ATOM   10038 C  CE1 . PHE F 1 9   ? 80.857  68.684  25.089  1.00 50.43  ? 9   PHE F CE1 1 
ATOM   10039 C  CE2 . PHE F 1 9   ? 78.859  69.827  25.767  1.00 48.37  ? 9   PHE F CE2 1 
ATOM   10040 C  CZ  . PHE F 1 9   ? 79.669  69.304  24.761  1.00 51.02  ? 9   PHE F CZ  1 
ATOM   10041 N  N   . GLN F 1 10  ? 82.622  67.865  30.749  1.00 46.04  ? 10  GLN F N   1 
ATOM   10042 C  CA  . GLN F 1 10  ? 83.618  67.594  31.778  1.00 41.52  ? 10  GLN F CA  1 
ATOM   10043 C  C   . GLN F 1 10  ? 84.936  68.264  31.397  1.00 45.41  ? 10  GLN F C   1 
ATOM   10044 O  O   . GLN F 1 10  ? 85.364  68.171  30.240  1.00 45.05  ? 10  GLN F O   1 
ATOM   10045 C  CB  . GLN F 1 10  ? 83.779  66.079  31.945  1.00 41.20  ? 10  GLN F CB  1 
ATOM   10046 C  CG  . GLN F 1 10  ? 85.060  65.602  32.622  1.00 45.68  ? 10  GLN F CG  1 
ATOM   10047 C  CD  . GLN F 1 10  ? 84.921  64.201  33.234  1.00 41.17  ? 10  GLN F CD  1 
ATOM   10048 O  OE1 . GLN F 1 10  ? 83.967  63.468  32.952  1.00 35.86  ? 10  GLN F OE1 1 
ATOM   10049 N  NE2 . GLN F 1 10  ? 85.862  63.841  34.098  1.00 42.83  ? 10  GLN F NE2 1 
ATOM   10050 N  N   . THR F 1 11  ? 85.564  68.981  32.329  1.00 40.34  ? 11  THR F N   1 
ATOM   10051 C  CA  . THR F 1 11  ? 86.912  69.526  32.128  1.00 48.63  ? 11  THR F CA  1 
ATOM   10052 C  C   . THR F 1 11  ? 87.896  68.743  32.992  1.00 49.45  ? 11  THR F C   1 
ATOM   10053 O  O   . THR F 1 11  ? 88.414  69.235  33.996  1.00 50.15  ? 11  THR F O   1 
ATOM   10054 C  CB  . THR F 1 11  ? 86.986  71.043  32.463  1.00 46.89  ? 11  THR F CB  1 
ATOM   10055 O  OG1 . THR F 1 11  ? 86.573  71.257  33.818  1.00 47.06  ? 11  THR F OG1 1 
ATOM   10056 C  CG2 . THR F 1 11  ? 86.142  71.876  31.518  1.00 41.50  ? 11  THR F CG2 1 
ATOM   10057 N  N   . GLY F 1 12  ? 88.142  67.500  32.593  1.00 52.30  ? 12  GLY F N   1 
ATOM   10058 C  CA  . GLY F 1 12  ? 89.084  66.664  33.312  1.00 48.81  ? 12  GLY F CA  1 
ATOM   10059 C  C   . GLY F 1 12  ? 88.620  66.359  34.721  1.00 51.21  ? 12  GLY F C   1 
ATOM   10060 O  O   . GLY F 1 12  ? 87.436  66.102  34.981  1.00 49.05  ? 12  GLY F O   1 
ATOM   10061 N  N   . THR F 1 13  ? 89.573  66.393  35.651  1.00 49.15  ? 13  THR F N   1 
ATOM   10062 C  CA  . THR F 1 13  ? 89.331  66.021  37.035  1.00 47.67  ? 13  THR F CA  1 
ATOM   10063 C  C   . THR F 1 13  ? 90.080  66.970  37.957  1.00 43.07  ? 13  THR F C   1 
ATOM   10064 O  O   . THR F 1 13  ? 90.891  67.789  37.523  1.00 40.87  ? 13  THR F O   1 
ATOM   10065 C  CB  . THR F 1 13  ? 89.772  64.577  37.315  1.00 48.56  ? 13  THR F CB  1 
ATOM   10066 O  OG1 . THR F 1 13  ? 90.994  64.308  36.611  1.00 54.96  ? 13  THR F OG1 1 
ATOM   10067 C  CG2 . THR F 1 13  ? 88.706  63.591  36.882  1.00 48.92  ? 13  THR F CG2 1 
ATOM   10068 N  N   . LEU F 1 14  ? 89.805  66.833  39.248  1.00 40.88  ? 14  LEU F N   1 
ATOM   10069 C  CA  . LEU F 1 14  ? 90.576  67.486  40.293  1.00 42.70  ? 14  LEU F CA  1 
ATOM   10070 C  C   . LEU F 1 14  ? 91.144  66.410  41.195  1.00 42.52  ? 14  LEU F C   1 
ATOM   10071 O  O   . LEU F 1 14  ? 90.407  65.526  41.644  1.00 44.20  ? 14  LEU F O   1 
ATOM   10072 C  CB  . LEU F 1 14  ? 89.723  68.469  41.116  1.00 41.94  ? 14  LEU F CB  1 
ATOM   10073 C  CG  . LEU F 1 14  ? 89.199  69.727  40.411  1.00 42.12  ? 14  LEU F CG  1 
ATOM   10074 C  CD1 . LEU F 1 14  ? 88.350  70.581  41.371  1.00 41.18  ? 14  LEU F CD1 1 
ATOM   10075 C  CD2 . LEU F 1 14  ? 90.346  70.545  39.835  1.00 37.29  ? 14  LEU F CD2 1 
ATOM   10076 N  N   . LYS F 1 15  ? 92.447  66.470  41.447  1.00 40.54  ? 15  LYS F N   1 
ATOM   10077 C  CA  . LYS F 1 15  ? 93.061  65.607  42.449  1.00 47.48  ? 15  LYS F CA  1 
ATOM   10078 C  C   . LYS F 1 15  ? 93.206  66.387  43.744  1.00 44.32  ? 15  LYS F C   1 
ATOM   10079 O  O   . LYS F 1 15  ? 93.792  67.472  43.759  1.00 40.94  ? 15  LYS F O   1 
ATOM   10080 C  CB  . LYS F 1 15  ? 94.422  65.067  42.004  1.00 49.09  ? 15  LYS F CB  1 
ATOM   10081 C  CG  . LYS F 1 15  ? 94.376  64.037  40.891  1.00 57.63  ? 15  LYS F CG  1 
ATOM   10082 C  CD  . LYS F 1 15  ? 95.734  63.348  40.765  1.00 61.72  ? 15  LYS F CD  1 
ATOM   10083 C  CE  . LYS F 1 15  ? 96.233  63.344  39.328  1.00 67.12  ? 15  LYS F CE  1 
ATOM   10084 N  NZ  . LYS F 1 15  ? 97.695  63.037  39.224  1.00 71.01  ? 15  LYS F NZ  1 
ATOM   10085 N  N   . CYS F 1 16  ? 92.675  65.828  44.822  1.00 43.03  ? 16  CYS F N   1 
ATOM   10086 C  CA  . CYS F 1 16  ? 92.672  66.486  46.118  1.00 48.36  ? 16  CYS F CA  1 
ATOM   10087 C  C   . CYS F 1 16  ? 92.675  65.398  47.180  1.00 50.17  ? 16  CYS F C   1 
ATOM   10088 O  O   . CYS F 1 16  ? 92.921  64.224  46.886  1.00 54.75  ? 16  CYS F O   1 
ATOM   10089 C  CB  . CYS F 1 16  ? 91.470  67.434  46.245  1.00 46.34  ? 16  CYS F CB  1 
ATOM   10090 S  SG  . CYS F 1 16  ? 89.852  66.624  46.036  1.00 49.42  ? 16  CYS F SG  1 
ATOM   10091 N  N   . ARG F 1 17  ? 92.409  65.785  48.418  1.00 52.69  ? 17  ARG F N   1 
ATOM   10092 C  CA  . ARG F 1 17  ? 92.169  64.821  49.479  1.00 53.43  ? 17  ARG F CA  1 
ATOM   10093 C  C   . ARG F 1 17  ? 90.676  64.560  49.611  1.00 55.66  ? 17  ARG F C   1 
ATOM   10094 O  O   . ARG F 1 17  ? 89.839  65.328  49.123  1.00 53.01  ? 17  ARG F O   1 
ATOM   10095 C  CB  . ARG F 1 17  ? 92.751  65.309  50.809  1.00 54.69  ? 17  ARG F CB  1 
ATOM   10096 C  CG  . ARG F 1 17  ? 94.259  65.168  50.884  1.00 61.60  ? 17  ARG F CG  1 
ATOM   10097 C  CD  . ARG F 1 17  ? 94.968  66.395  50.352  1.00 62.38  ? 17  ARG F CD  1 
ATOM   10098 N  NE  . ARG F 1 17  ? 95.434  67.264  51.425  1.00 68.93  ? 17  ARG F NE  1 
ATOM   10099 C  CZ  . ARG F 1 17  ? 95.723  68.551  51.272  1.00 73.71  ? 17  ARG F CZ  1 
ATOM   10100 N  NH1 . ARG F 1 17  ? 95.589  69.156  50.102  1.00 68.31  ? 17  ARG F NH1 1 
ATOM   10101 N  NH2 . ARG F 1 17  ? 96.152  69.249  52.321  1.00 77.10  ? 17  ARG F NH2 1 
ATOM   10102 N  N   . VAL F 1 18  ? 90.352  63.440  50.261  1.00 53.18  ? 18  VAL F N   1 
ATOM   10103 C  CA  . VAL F 1 18  ? 88.956  63.115  50.522  1.00 52.23  ? 18  VAL F CA  1 
ATOM   10104 C  C   . VAL F 1 18  ? 88.324  64.187  51.400  1.00 53.33  ? 18  VAL F C   1 
ATOM   10105 O  O   . VAL F 1 18  ? 87.159  64.559  51.214  1.00 52.36  ? 18  VAL F O   1 
ATOM   10106 C  CB  . VAL F 1 18  ? 88.847  61.720  51.166  1.00 54.83  ? 18  VAL F CB  1 
ATOM   10107 C  CG1 . VAL F 1 18  ? 87.417  61.447  51.597  1.00 56.95  ? 18  VAL F CG1 1 
ATOM   10108 C  CG2 . VAL F 1 18  ? 89.330  60.650  50.197  1.00 57.10  ? 18  VAL F CG2 1 
ATOM   10109 N  N   . CYS F 1 19  ? 89.092  64.714  52.356  1.00 47.68  ? 19  CYS F N   1 
ATOM   10110 C  CA  . CYS F 1 19  ? 88.553  65.666  53.317  1.00 49.33  ? 19  CYS F CA  1 
ATOM   10111 C  C   . CYS F 1 19  ? 88.096  66.958  52.645  1.00 50.57  ? 19  CYS F C   1 
ATOM   10112 O  O   . CYS F 1 19  ? 87.194  67.632  53.154  1.00 49.83  ? 19  CYS F O   1 
ATOM   10113 C  CB  . CYS F 1 19  ? 89.606  65.964  54.382  1.00 51.74  ? 19  CYS F CB  1 
ATOM   10114 S  SG  . CYS F 1 19  ? 91.083  66.746  53.683  1.00 52.04  ? 19  CYS F SG  1 
ATOM   10115 N  N   . ASN F 1 20  ? 88.699  67.320  51.507  1.00 48.59  ? 20  ASN F N   1 
ATOM   10116 C  CA  . ASN F 1 20  ? 88.245  68.493  50.769  1.00 51.25  ? 20  ASN F CA  1 
ATOM   10117 C  C   . ASN F 1 20  ? 86.820  68.329  50.258  1.00 50.19  ? 20  ASN F C   1 
ATOM   10118 O  O   . ASN F 1 20  ? 86.135  69.334  50.022  1.00 44.47  ? 20  ASN F O   1 
ATOM   10119 C  CB  . ASN F 1 20  ? 89.177  68.775  49.587  1.00 46.93  ? 20  ASN F CB  1 
ATOM   10120 C  CG  . ASN F 1 20  ? 90.628  68.920  50.007  1.00 52.99  ? 20  ASN F CG  1 
ATOM   10121 O  OD1 . ASN F 1 20  ? 91.519  68.306  49.417  1.00 51.10  ? 20  ASN F OD1 1 
ATOM   10122 N  ND2 . ASN F 1 20  ? 90.874  69.730  51.034  1.00 48.52  ? 20  ASN F ND2 1 
ATOM   10123 N  N   . ILE F 1 21  ? 86.368  67.087  50.090  1.00 49.64  ? 21  ILE F N   1 
ATOM   10124 C  CA  . ILE F 1 21  ? 85.063  66.772  49.524  1.00 49.17  ? 21  ILE F CA  1 
ATOM   10125 C  C   . ILE F 1 21  ? 84.081  66.319  50.604  1.00 44.28  ? 21  ILE F C   1 
ATOM   10126 O  O   . ILE F 1 21  ? 82.939  66.780  50.649  1.00 44.32  ? 21  ILE F O   1 
ATOM   10127 C  CB  . ILE F 1 21  ? 85.198  65.710  48.405  1.00 48.02  ? 21  ILE F CB  1 
ATOM   10128 C  CG1 . ILE F 1 21  ? 85.735  66.347  47.119  1.00 50.65  ? 21  ILE F CG1 1 
ATOM   10129 C  CG2 . ILE F 1 21  ? 83.865  65.030  48.135  1.00 46.37  ? 21  ILE F CG2 1 
ATOM   10130 C  CD1 . ILE F 1 21  ? 85.065  67.675  46.746  1.00 50.41  ? 21  ILE F CD1 1 
ATOM   10131 N  N   . LYS F 1 22  ? 84.511  65.417  51.490  1.00 45.71  ? 22  LYS F N   1 
ATOM   10132 C  CA  . LYS F 1 22  ? 83.720  65.015  52.652  1.00 45.49  ? 22  LYS F CA  1 
ATOM   10133 C  C   . LYS F 1 22  ? 84.467  65.481  53.901  1.00 51.40  ? 22  LYS F C   1 
ATOM   10134 O  O   . LYS F 1 22  ? 85.559  64.985  54.196  1.00 50.48  ? 22  LYS F O   1 
ATOM   10135 C  CB  . LYS F 1 22  ? 83.471  63.505  52.663  1.00 44.54  ? 22  LYS F CB  1 
ATOM   10136 C  CG  . LYS F 1 22  ? 83.107  62.938  51.289  1.00 47.06  ? 22  LYS F CG  1 
ATOM   10137 C  CD  . LYS F 1 22  ? 82.851  61.414  51.305  1.00 46.76  ? 22  LYS F CD  1 
ATOM   10138 C  CE  . LYS F 1 22  ? 82.478  60.897  49.903  1.00 47.58  ? 22  LYS F CE  1 
ATOM   10139 N  NZ  . LYS F 1 22  ? 81.751  59.586  49.898  1.00 44.63  ? 22  LYS F NZ  1 
ATOM   10140 N  N   . MET F 1 23  ? 83.880  66.441  54.621  1.00 48.73  ? 23  MET F N   1 
ATOM   10141 C  CA  . MET F 1 23  ? 84.594  67.139  55.686  1.00 50.57  ? 23  MET F CA  1 
ATOM   10142 C  C   . MET F 1 23  ? 85.011  66.182  56.801  1.00 53.94  ? 23  MET F C   1 
ATOM   10143 O  O   . MET F 1 23  ? 84.207  65.374  57.278  1.00 48.75  ? 23  MET F O   1 
ATOM   10144 C  CB  . MET F 1 23  ? 83.721  68.267  56.252  1.00 46.61  ? 23  MET F CB  1 
ATOM   10145 C  CG  . MET F 1 23  ? 84.416  69.143  57.292  1.00 48.97  ? 23  MET F CG  1 
ATOM   10146 S  SD  . MET F 1 23  ? 83.329  70.366  58.047  1.00 56.47  ? 23  MET F SD  1 
ATOM   10147 C  CE  . MET F 1 23  ? 82.585  69.398  59.360  1.00 42.83  ? 23  MET F CE  1 
ATOM   10148 N  N   . ASN F 1 24  ? 86.289  66.275  57.202  1.00 52.84  ? 24  ASN F N   1 
ATOM   10149 C  CA  . ASN F 1 24  ? 86.860  65.497  58.310  1.00 52.30  ? 24  ASN F CA  1 
ATOM   10150 C  C   . ASN F 1 24  ? 86.785  63.989  58.065  1.00 53.81  ? 24  ASN F C   1 
ATOM   10151 O  O   . ASN F 1 24  ? 86.648  63.207  59.012  1.00 57.24  ? 24  ASN F O   1 
ATOM   10152 C  CB  . ASN F 1 24  ? 86.193  65.853  59.648  1.00 48.40  ? 24  ASN F CB  1 
ATOM   10153 C  CG  . ASN F 1 24  ? 86.274  67.349  59.971  1.00 53.88  ? 24  ASN F CG  1 
ATOM   10154 O  OD1 . ASN F 1 24  ? 87.178  68.059  59.502  1.00 51.30  ? 24  ASN F OD1 1 
ATOM   10155 N  ND2 . ASN F 1 24  ? 85.317  67.834  60.766  1.00 46.38  ? 24  ASN F ND2 1 
ATOM   10156 N  N   . ALA F 1 25  ? 86.880  63.567  56.802  1.00 47.82  ? 25  ALA F N   1 
ATOM   10157 C  CA  . ALA F 1 25  ? 86.778  62.159  56.435  1.00 57.53  ? 25  ALA F CA  1 
ATOM   10158 C  C   . ALA F 1 25  ? 88.119  61.529  56.060  1.00 59.27  ? 25  ALA F C   1 
ATOM   10159 O  O   . ALA F 1 25  ? 88.147  60.361  55.650  1.00 60.54  ? 25  ALA F O   1 
ATOM   10160 C  CB  . ALA F 1 25  ? 85.783  61.978  55.280  1.00 53.15  ? 25  ALA F CB  1 
ATOM   10161 N  N   . GLY F 1 26  ? 89.224  62.259  56.189  1.00 56.30  ? 26  GLY F N   1 
ATOM   10162 C  CA  . GLY F 1 26  ? 90.524  61.652  55.982  1.00 58.48  ? 26  GLY F CA  1 
ATOM   10163 C  C   . GLY F 1 26  ? 91.374  62.314  54.919  1.00 57.82  ? 26  GLY F C   1 
ATOM   10164 O  O   . GLY F 1 26  ? 90.858  62.935  53.981  1.00 53.96  ? 26  GLY F O   1 
ATOM   10165 N  N   . LEU F 1 27  ? 92.687  62.161  55.044  1.00 53.31  ? 27  LEU F N   1 
ATOM   10166 C  CA  . LEU F 1 27  ? 93.627  62.819  54.155  1.00 55.80  ? 27  LEU F CA  1 
ATOM   10167 C  C   . LEU F 1 27  ? 93.999  61.958  52.947  1.00 57.17  ? 27  LEU F C   1 
ATOM   10168 O  O   . LEU F 1 27  ? 94.922  62.314  52.206  1.00 53.34  ? 27  LEU F O   1 
ATOM   10169 C  CB  . LEU F 1 27  ? 94.871  63.222  54.948  1.00 59.63  ? 27  LEU F CB  1 
ATOM   10170 C  CG  . LEU F 1 27  ? 94.557  64.027  56.220  1.00 58.70  ? 27  LEU F CG  1 
ATOM   10171 C  CD1 . LEU F 1 27  ? 95.818  64.432  56.969  1.00 53.84  ? 27  LEU F CD1 1 
ATOM   10172 C  CD2 . LEU F 1 27  ? 93.712  65.255  55.891  1.00 54.94  ? 27  LEU F CD2 1 
ATOM   10173 N  N   . ASP F 1 28  ? 93.289  60.853  52.719  1.00 56.47  ? 28  ASP F N   1 
ATOM   10174 C  CA  . ASP F 1 28  ? 93.569  59.994  51.573  1.00 53.68  ? 28  ASP F CA  1 
ATOM   10175 C  C   . ASP F 1 28  ? 93.364  60.734  50.258  1.00 59.26  ? 28  ASP F C   1 
ATOM   10176 O  O   . ASP F 1 28  ? 92.528  61.634  50.150  1.00 58.11  ? 28  ASP F O   1 
ATOM   10177 C  CB  . ASP F 1 28  ? 92.669  58.764  51.595  1.00 59.72  ? 28  ASP F CB  1 
ATOM   10178 C  CG  . ASP F 1 28  ? 93.210  57.671  52.471  1.00 63.89  ? 28  ASP F CG  1 
ATOM   10179 O  OD1 . ASP F 1 28  ? 94.427  57.689  52.765  1.00 66.28  ? 28  ASP F OD1 1 
ATOM   10180 O  OD2 . ASP F 1 28  ? 92.414  56.785  52.850  1.00 66.96  ? 28  ASP F OD2 1 
ATOM   10181 N  N   . ASP F 1 29  ? 94.124  60.329  49.245  1.00 56.93  ? 29  ASP F N   1 
ATOM   10182 C  CA  . ASP F 1 29  ? 94.003  60.947  47.938  1.00 57.12  ? 29  ASP F CA  1 
ATOM   10183 C  C   . ASP F 1 29  ? 92.618  60.695  47.353  1.00 57.95  ? 29  ASP F C   1 
ATOM   10184 O  O   . ASP F 1 29  ? 91.931  59.721  47.687  1.00 51.52  ? 29  ASP F O   1 
ATOM   10185 C  CB  . ASP F 1 29  ? 95.078  60.421  46.988  1.00 61.70  ? 29  ASP F CB  1 
ATOM   10186 C  CG  . ASP F 1 29  ? 96.459  60.914  47.350  1.00 65.15  ? 29  ASP F CG  1 
ATOM   10187 O  OD1 . ASP F 1 29  ? 96.645  61.351  48.508  1.00 67.15  ? 29  ASP F OD1 1 
ATOM   10188 O  OD2 . ASP F 1 29  ? 97.360  60.858  46.487  1.00 73.55  ? 29  ASP F OD2 1 
ATOM   10189 N  N   . TYR F 1 30  ? 92.219  61.593  46.455  1.00 54.47  ? 30  TYR F N   1 
ATOM   10190 C  CA  . TYR F 1 30  ? 90.870  61.591  45.912  1.00 52.86  ? 30  TYR F CA  1 
ATOM   10191 C  C   . TYR F 1 30  ? 90.892  62.328  44.582  1.00 49.72  ? 30  TYR F C   1 
ATOM   10192 O  O   . TYR F 1 30  ? 91.671  63.268  44.387  1.00 49.07  ? 30  TYR F O   1 
ATOM   10193 C  CB  . TYR F 1 30  ? 89.889  62.246  46.896  1.00 53.74  ? 30  TYR F CB  1 
ATOM   10194 C  CG  . TYR F 1 30  ? 88.422  61.891  46.725  1.00 52.43  ? 30  TYR F CG  1 
ATOM   10195 C  CD1 . TYR F 1 30  ? 87.974  60.587  46.863  1.00 51.74  ? 30  TYR F CD1 1 
ATOM   10196 C  CD2 . TYR F 1 30  ? 87.478  62.882  46.477  1.00 51.72  ? 30  TYR F CD2 1 
ATOM   10197 C  CE1 . TYR F 1 30  ? 86.624  60.276  46.736  1.00 52.29  ? 30  TYR F CE1 1 
ATOM   10198 C  CE2 . TYR F 1 30  ? 86.141  62.582  46.349  1.00 50.77  ? 30  TYR F CE2 1 
ATOM   10199 C  CZ  . TYR F 1 30  ? 85.716  61.282  46.473  1.00 52.14  ? 30  TYR F CZ  1 
ATOM   10200 O  OH  . TYR F 1 30  ? 84.377  61.000  46.342  1.00 51.25  ? 30  TYR F OH  1 
ATOM   10201 N  N   . GLU F 1 31  ? 90.038  61.882  43.668  1.00 47.45  ? 31  GLU F N   1 
ATOM   10202 C  CA  . GLU F 1 31  ? 89.918  62.496  42.359  1.00 46.23  ? 31  GLU F CA  1 
ATOM   10203 C  C   . GLU F 1 31  ? 88.442  62.629  42.026  1.00 43.64  ? 31  GLU F C   1 
ATOM   10204 O  O   . GLU F 1 31  ? 87.661  61.718  42.308  1.00 41.90  ? 31  GLU F O   1 
ATOM   10205 C  CB  . GLU F 1 31  ? 90.639  61.666  41.301  1.00 51.23  ? 31  GLU F CB  1 
ATOM   10206 C  CG  . GLU F 1 31  ? 90.823  62.368  39.978  1.00 49.57  ? 31  GLU F CG  1 
ATOM   10207 C  CD  . GLU F 1 31  ? 91.614  61.524  39.011  1.00 55.01  ? 31  GLU F CD  1 
ATOM   10208 O  OE1 . GLU F 1 31  ? 91.784  60.319  39.301  1.00 56.56  ? 31  GLU F OE1 1 
ATOM   10209 O  OE2 . GLU F 1 31  ? 92.050  62.053  37.967  1.00 53.34  ? 31  GLU F OE2 1 
ATOM   10210 N  N   . ILE F 1 32  ? 88.066  63.761  41.433  1.00 43.21  ? 32  ILE F N   1 
ATOM   10211 C  CA  . ILE F 1 32  ? 86.661  64.068  41.160  1.00 38.72  ? 32  ILE F CA  1 
ATOM   10212 C  C   . ILE F 1 32  ? 86.494  64.640  39.758  1.00 40.99  ? 32  ILE F C   1 
ATOM   10213 O  O   . ILE F 1 32  ? 87.349  65.407  39.288  1.00 42.89  ? 32  ILE F O   1 
ATOM   10214 C  CB  . ILE F 1 32  ? 86.090  65.039  42.212  1.00 44.38  ? 32  ILE F CB  1 
ATOM   10215 C  CG1 . ILE F 1 32  ? 86.940  66.318  42.318  1.00 41.40  ? 32  ILE F CG1 1 
ATOM   10216 C  CG2 . ILE F 1 32  ? 85.951  64.363  43.559  1.00 42.33  ? 32  ILE F CG2 1 
ATOM   10217 C  CD1 . ILE F 1 32  ? 86.200  67.485  42.979  1.00 43.76  ? 32  ILE F CD1 1 
ATOM   10218 N  N   . PRO F 1 33  ? 85.411  64.314  39.062  1.00 39.65  ? 33  PRO F N   1 
ATOM   10219 C  CA  . PRO F 1 33  ? 85.156  64.944  37.765  1.00 41.43  ? 33  PRO F CA  1 
ATOM   10220 C  C   . PRO F 1 33  ? 84.787  66.409  37.941  1.00 40.08  ? 33  PRO F C   1 
ATOM   10221 O  O   . PRO F 1 33  ? 84.356  66.839  39.010  1.00 40.43  ? 33  PRO F O   1 
ATOM   10222 C  CB  . PRO F 1 33  ? 83.975  64.141  37.210  1.00 42.51  ? 33  PRO F CB  1 
ATOM   10223 C  CG  . PRO F 1 33  ? 83.246  63.691  38.451  1.00 41.08  ? 33  PRO F CG  1 
ATOM   10224 C  CD  . PRO F 1 33  ? 84.329  63.393  39.456  1.00 40.62  ? 33  PRO F CD  1 
ATOM   10225 N  N   . VAL F 1 34  ? 84.966  67.181  36.872  1.00 38.13  ? 34  VAL F N   1 
ATOM   10226 C  CA  . VAL F 1 34  ? 84.515  68.572  36.853  1.00 42.08  ? 34  VAL F CA  1 
ATOM   10227 C  C   . VAL F 1 34  ? 83.411  68.729  35.810  1.00 41.28  ? 34  VAL F C   1 
ATOM   10228 O  O   . VAL F 1 34  ? 83.696  69.093  34.659  1.00 39.42  ? 34  VAL F O   1 
ATOM   10229 C  CB  . VAL F 1 34  ? 85.669  69.549  36.578  1.00 39.18  ? 34  VAL F CB  1 
ATOM   10230 C  CG1 . VAL F 1 34  ? 85.155  70.994  36.576  1.00 39.16  ? 34  VAL F CG1 1 
ATOM   10231 C  CG2 . VAL F 1 34  ? 86.757  69.389  37.612  1.00 36.72  ? 34  VAL F CG2 1 
ATOM   10232 N  N   . PRO F 1 35  ? 82.151  68.473  36.166  1.00 40.11  ? 35  PRO F N   1 
ATOM   10233 C  CA  . PRO F 1 35  ? 81.056  68.637  35.202  1.00 41.03  ? 35  PRO F CA  1 
ATOM   10234 C  C   . PRO F 1 35  ? 80.824  70.087  34.803  1.00 39.32  ? 35  PRO F C   1 
ATOM   10235 O  O   . PRO F 1 35  ? 81.127  71.027  35.541  1.00 40.08  ? 35  PRO F O   1 
ATOM   10236 C  CB  . PRO F 1 35  ? 79.835  68.092  35.957  1.00 34.94  ? 35  PRO F CB  1 
ATOM   10237 C  CG  . PRO F 1 35  ? 80.377  67.290  37.038  1.00 38.57  ? 35  PRO F CG  1 
ATOM   10238 C  CD  . PRO F 1 35  ? 81.654  67.961  37.447  1.00 40.04  ? 35  PRO F CD  1 
ATOM   10239 N  N   . TRP F 1 36  ? 80.284  70.250  33.600  1.00 43.90  ? 36  TRP F N   1 
ATOM   10240 C  CA  . TRP F 1 36  ? 79.659  71.489  33.161  1.00 38.09  ? 36  TRP F CA  1 
ATOM   10241 C  C   . TRP F 1 36  ? 78.621  71.111  32.117  1.00 39.51  ? 36  TRP F C   1 
ATOM   10242 O  O   . TRP F 1 36  ? 78.557  69.965  31.666  1.00 43.23  ? 36  TRP F O   1 
ATOM   10243 C  CB  . TRP F 1 36  ? 80.677  72.499  32.631  1.00 37.77  ? 36  TRP F CB  1 
ATOM   10244 C  CG  . TRP F 1 36  ? 81.417  72.091  31.396  1.00 42.63  ? 36  TRP F CG  1 
ATOM   10245 C  CD1 . TRP F 1 36  ? 82.530  71.307  31.330  1.00 41.67  ? 36  TRP F CD1 1 
ATOM   10246 C  CD2 . TRP F 1 36  ? 81.116  72.479  30.048  1.00 42.47  ? 36  TRP F CD2 1 
ATOM   10247 N  NE1 . TRP F 1 36  ? 82.935  71.175  30.029  1.00 44.66  ? 36  TRP F NE1 1 
ATOM   10248 C  CE2 . TRP F 1 36  ? 82.090  71.892  29.219  1.00 46.35  ? 36  TRP F CE2 1 
ATOM   10249 C  CE3 . TRP F 1 36  ? 80.118  73.269  29.462  1.00 42.29  ? 36  TRP F CE3 1 
ATOM   10250 C  CZ2 . TRP F 1 36  ? 82.088  72.052  27.827  1.00 44.10  ? 36  TRP F CZ2 1 
ATOM   10251 C  CZ3 . TRP F 1 36  ? 80.116  73.429  28.081  1.00 43.29  ? 36  TRP F CZ3 1 
ATOM   10252 C  CH2 . TRP F 1 36  ? 81.097  72.821  27.280  1.00 44.90  ? 36  TRP F CH2 1 
ATOM   10253 N  N   . TYR F 1 37  ? 77.777  72.062  31.748  1.00 36.38  ? 37  TYR F N   1 
ATOM   10254 C  CA  . TYR F 1 37  ? 76.566  71.664  31.056  1.00 35.38  ? 37  TYR F CA  1 
ATOM   10255 C  C   . TYR F 1 37  ? 76.276  72.607  29.909  1.00 37.49  ? 37  TYR F C   1 
ATOM   10256 O  O   . TYR F 1 37  ? 76.562  73.801  29.978  1.00 38.16  ? 37  TYR F O   1 
ATOM   10257 C  CB  . TYR F 1 37  ? 75.374  71.611  32.017  1.00 38.05  ? 37  TYR F CB  1 
ATOM   10258 C  CG  . TYR F 1 37  ? 75.661  70.841  33.284  1.00 37.75  ? 37  TYR F CG  1 
ATOM   10259 C  CD1 . TYR F 1 37  ? 75.551  69.452  33.319  1.00 36.19  ? 37  TYR F CD1 1 
ATOM   10260 C  CD2 . TYR F 1 37  ? 76.055  71.497  34.442  1.00 33.77  ? 37  TYR F CD2 1 
ATOM   10261 C  CE1 . TYR F 1 37  ? 75.814  68.740  34.478  1.00 31.84  ? 37  TYR F CE1 1 
ATOM   10262 C  CE2 . TYR F 1 37  ? 76.320  70.791  35.611  1.00 33.79  ? 37  TYR F CE2 1 
ATOM   10263 C  CZ  . TYR F 1 37  ? 76.201  69.417  35.625  1.00 36.88  ? 37  TYR F CZ  1 
ATOM   10264 O  OH  . TYR F 1 37  ? 76.465  68.717  36.795  1.00 36.41  ? 37  TYR F OH  1 
ATOM   10265 N  N   . LEU F 1 38  ? 75.729  72.047  28.842  1.00 39.26  ? 38  LEU F N   1 
ATOM   10266 C  CA  . LEU F 1 38  ? 75.261  72.815  27.705  1.00 38.49  ? 38  LEU F CA  1 
ATOM   10267 C  C   . LEU F 1 38  ? 73.790  72.501  27.525  1.00 37.39  ? 38  LEU F C   1 
ATOM   10268 O  O   . LEU F 1 38  ? 73.388  71.338  27.610  1.00 39.22  ? 38  LEU F O   1 
ATOM   10269 C  CB  . LEU F 1 38  ? 76.051  72.474  26.435  1.00 40.38  ? 38  LEU F CB  1 
ATOM   10270 C  CG  . LEU F 1 38  ? 75.399  72.778  25.083  1.00 41.24  ? 38  LEU F CG  1 
ATOM   10271 C  CD1 . LEU F 1 38  ? 75.513  74.246  24.749  1.00 38.39  ? 38  LEU F CD1 1 
ATOM   10272 C  CD2 . LEU F 1 38  ? 76.031  71.938  23.971  1.00 45.55  ? 38  LEU F CD2 1 
ATOM   10273 N  N   . ILE F 1 39  ? 72.984  73.529  27.317  1.00 35.92  ? 39  ILE F N   1 
ATOM   10274 C  CA  . ILE F 1 39  ? 71.614  73.333  26.876  1.00 33.54  ? 39  ILE F CA  1 
ATOM   10275 C  C   . ILE F 1 39  ? 71.493  73.972  25.505  1.00 37.11  ? 39  ILE F C   1 
ATOM   10276 O  O   . ILE F 1 39  ? 71.873  75.135  25.315  1.00 36.97  ? 39  ILE F O   1 
ATOM   10277 C  CB  . ILE F 1 39  ? 70.575  73.902  27.860  1.00 38.64  ? 39  ILE F CB  1 
ATOM   10278 C  CG1 . ILE F 1 39  ? 70.704  73.236  29.240  1.00 34.94  ? 39  ILE F CG1 1 
ATOM   10279 C  CG2 . ILE F 1 39  ? 69.175  73.670  27.325  1.00 38.31  ? 39  ILE F CG2 1 
ATOM   10280 C  CD1 . ILE F 1 39  ? 71.712  73.904  30.161  1.00 39.46  ? 39  ILE F CD1 1 
ATOM   10281 N  N   . THR F 1 40  ? 71.041  73.185  24.539  1.00 36.88  ? 40  THR F N   1 
ATOM   10282 C  CA  . THR F 1 40  ? 70.687  73.688  23.224  1.00 38.27  ? 40  THR F CA  1 
ATOM   10283 C  C   . THR F 1 40  ? 69.188  73.937  23.227  1.00 36.94  ? 40  THR F C   1 
ATOM   10284 O  O   . THR F 1 40  ? 68.407  73.057  23.594  1.00 40.86  ? 40  THR F O   1 
ATOM   10285 C  CB  . THR F 1 40  ? 71.079  72.691  22.130  1.00 42.96  ? 40  THR F CB  1 
ATOM   10286 O  OG1 . THR F 1 40  ? 70.524  71.400  22.433  1.00 45.40  ? 40  THR F OG1 1 
ATOM   10287 C  CG2 . THR F 1 40  ? 72.604  72.585  22.037  1.00 34.53  ? 40  THR F CG2 1 
ATOM   10288 N  N   . HIS F 1 41  ? 68.791  75.139  22.844  1.00 38.76  ? 41  HIS F N   1 
ATOM   10289 C  CA  . HIS F 1 41  ? 67.420  75.553  22.979  1.00 37.64  ? 41  HIS F CA  1 
ATOM   10290 C  C   . HIS F 1 41  ? 67.122  76.380  21.740  1.00 37.95  ? 41  HIS F C   1 
ATOM   10291 O  O   . HIS F 1 41  ? 68.002  77.111  21.268  1.00 37.22  ? 41  HIS F O   1 
ATOM   10292 C  CB  . HIS F 1 41  ? 67.229  76.375  24.271  1.00 37.21  ? 41  HIS F CB  1 
ATOM   10293 C  CG  . HIS F 1 41  ? 65.808  76.702  24.607  1.00 33.99  ? 41  HIS F CG  1 
ATOM   10294 N  ND1 . HIS F 1 41  ? 65.121  77.738  24.016  1.00 37.99  ? 41  HIS F ND1 1 
ATOM   10295 C  CD2 . HIS F 1 41  ? 64.955  76.148  25.504  1.00 39.12  ? 41  HIS F CD2 1 
ATOM   10296 C  CE1 . HIS F 1 41  ? 63.900  77.799  24.521  1.00 38.12  ? 41  HIS F CE1 1 
ATOM   10297 N  NE2 . HIS F 1 41  ? 63.775  76.846  25.429  1.00 34.58  ? 41  HIS F NE2 1 
ATOM   10298 N  N   . PRO F 1 42  ? 65.917  76.261  21.178  1.00 36.84  ? 42  PRO F N   1 
ATOM   10299 C  CA  . PRO F 1 42  ? 65.565  77.091  20.014  1.00 36.74  ? 42  PRO F CA  1 
ATOM   10300 C  C   . PRO F 1 42  ? 65.879  78.562  20.204  1.00 40.70  ? 42  PRO F C   1 
ATOM   10301 O  O   . PRO F 1 42  ? 66.298  79.232  19.252  1.00 43.31  ? 42  PRO F O   1 
ATOM   10302 C  CB  . PRO F 1 42  ? 64.051  76.863  19.866  1.00 38.43  ? 42  PRO F CB  1 
ATOM   10303 C  CG  . PRO F 1 42  ? 63.798  75.539  20.484  1.00 37.67  ? 42  PRO F CG  1 
ATOM   10304 C  CD  . PRO F 1 42  ? 64.850  75.316  21.545  1.00 37.29  ? 42  PRO F CD  1 
ATOM   10305 N  N   . LYS F 1 43  ? 65.691  79.090  21.415  1.00 42.59  ? 43  LYS F N   1 
ATOM   10306 C  CA  . LYS F 1 43  ? 65.932  80.509  21.648  1.00 37.27  ? 43  LYS F CA  1 
ATOM   10307 C  C   . LYS F 1 43  ? 67.390  80.814  21.954  1.00 33.36  ? 43  LYS F C   1 
ATOM   10308 O  O   . LYS F 1 43  ? 67.735  81.991  22.100  1.00 36.71  ? 43  LYS F O   1 
ATOM   10309 C  CB  . LYS F 1 43  ? 65.032  81.018  22.777  1.00 41.34  ? 43  LYS F CB  1 
ATOM   10310 C  CG  . LYS F 1 43  ? 63.573  80.626  22.595  1.00 41.71  ? 43  LYS F CG  1 
ATOM   10311 C  CD  . LYS F 1 43  ? 62.637  81.657  23.183  1.00 48.08  ? 43  LYS F CD  1 
ATOM   10312 C  CE  . LYS F 1 43  ? 61.196  81.156  23.193  1.00 58.69  ? 43  LYS F CE  1 
ATOM   10313 N  NZ  . LYS F 1 43  ? 60.258  82.195  23.718  1.00 67.20  ? 43  LYS F NZ  1 
ATOM   10314 N  N   . GLY F 1 44  ? 68.247  79.810  22.040  1.00 33.53  ? 44  GLY F N   1 
ATOM   10315 C  CA  . GLY F 1 44  ? 69.671  80.060  22.178  1.00 33.70  ? 44  GLY F CA  1 
ATOM   10316 C  C   . GLY F 1 44  ? 70.361  78.929  22.909  1.00 36.33  ? 44  GLY F C   1 
ATOM   10317 O  O   . GLY F 1 44  ? 69.733  78.071  23.529  1.00 38.50  ? 44  GLY F O   1 
ATOM   10318 N  N   . ASN F 1 45  ? 71.688  78.931  22.811  1.00 34.82  ? 45  ASN F N   1 
ATOM   10319 C  CA  . ASN F 1 45  ? 72.507  77.987  23.558  1.00 37.57  ? 45  ASN F CA  1 
ATOM   10320 C  C   . ASN F 1 45  ? 72.920  78.593  24.896  1.00 37.56  ? 45  ASN F C   1 
ATOM   10321 O  O   . ASN F 1 45  ? 73.196  79.794  24.996  1.00 34.94  ? 45  ASN F O   1 
ATOM   10322 C  CB  . ASN F 1 45  ? 73.753  77.583  22.773  1.00 32.96  ? 45  ASN F CB  1 
ATOM   10323 C  CG  . ASN F 1 45  ? 73.415  76.950  21.440  1.00 39.30  ? 45  ASN F CG  1 
ATOM   10324 O  OD1 . ASN F 1 45  ? 72.634  76.008  21.376  1.00 39.19  ? 45  ASN F OD1 1 
ATOM   10325 N  ND2 . ASN F 1 45  ? 73.991  77.479  20.365  1.00 36.75  ? 45  ASN F ND2 1 
ATOM   10326 N  N   . VAL F 1 46  ? 72.974  77.742  25.912  1.00 34.29  ? 46  VAL F N   1 
ATOM   10327 C  CA  . VAL F 1 46  ? 73.270  78.129  27.280  1.00 33.58  ? 46  VAL F CA  1 
ATOM   10328 C  C   . VAL F 1 46  ? 74.399  77.256  27.791  1.00 36.45  ? 46  VAL F C   1 
ATOM   10329 O  O   . VAL F 1 46  ? 74.291  76.020  27.768  1.00 35.18  ? 46  VAL F O   1 
ATOM   10330 C  CB  . VAL F 1 46  ? 72.045  77.966  28.195  1.00 35.35  ? 46  VAL F CB  1 
ATOM   10331 C  CG1 . VAL F 1 46  ? 72.419  78.336  29.624  1.00 33.45  ? 46  VAL F CG1 1 
ATOM   10332 C  CG2 . VAL F 1 46  ? 70.884  78.783  27.678  1.00 35.90  ? 46  VAL F CG2 1 
ATOM   10333 N  N   . VAL F 1 47  ? 75.463  77.897  28.273  1.00 32.66  ? 47  VAL F N   1 
ATOM   10334 C  CA  . VAL F 1 47  ? 76.541  77.225  28.989  1.00 36.04  ? 47  VAL F CA  1 
ATOM   10335 C  C   . VAL F 1 47  ? 76.346  77.453  30.486  1.00 36.84  ? 47  VAL F C   1 
ATOM   10336 O  O   . VAL F 1 47  ? 76.120  78.588  30.926  1.00 34.68  ? 47  VAL F O   1 
ATOM   10337 C  CB  . VAL F 1 47  ? 77.919  77.738  28.533  1.00 36.51  ? 47  VAL F CB  1 
ATOM   10338 C  CG1 . VAL F 1 47  ? 79.005  77.183  29.435  1.00 37.61  ? 47  VAL F CG1 1 
ATOM   10339 C  CG2 . VAL F 1 47  ? 78.190  77.354  27.079  1.00 36.69  ? 47  VAL F CG2 1 
ATOM   10340 N  N   . ILE F 1 48  ? 76.435  76.381  31.267  1.00 34.06  ? 48  ILE F N   1 
ATOM   10341 C  CA  . ILE F 1 48  ? 76.431  76.452  32.726  1.00 30.64  ? 48  ILE F CA  1 
ATOM   10342 C  C   . ILE F 1 48  ? 77.851  76.235  33.240  1.00 33.16  ? 48  ILE F C   1 
ATOM   10343 O  O   . ILE F 1 48  ? 78.385  75.125  33.145  1.00 34.99  ? 48  ILE F O   1 
ATOM   10344 C  CB  . ILE F 1 48  ? 75.486  75.420  33.345  1.00 31.97  ? 48  ILE F CB  1 
ATOM   10345 C  CG1 . ILE F 1 48  ? 74.047  75.623  32.857  1.00 30.17  ? 48  ILE F CG1 1 
ATOM   10346 C  CG2 . ILE F 1 48  ? 75.602  75.472  34.859  1.00 26.58  ? 48  ILE F CG2 1 
ATOM   10347 C  CD1 . ILE F 1 48  ? 73.061  74.766  33.602  1.00 28.06  ? 48  ILE F CD1 1 
ATOM   10348 N  N   . ASP F 1 49  ? 78.451  77.298  33.792  1.00 32.94  ? 49  ASP F N   1 
ATOM   10349 C  CA  . ASP F 1 49  ? 79.735  77.299  34.498  1.00 33.82  ? 49  ASP F CA  1 
ATOM   10350 C  C   . ASP F 1 49  ? 80.941  77.143  33.571  1.00 36.76  ? 49  ASP F C   1 
ATOM   10351 O  O   . ASP F 1 49  ? 81.799  78.033  33.516  1.00 34.81  ? 49  ASP F O   1 
ATOM   10352 C  CB  . ASP F 1 49  ? 79.767  76.211  35.581  1.00 30.80  ? 49  ASP F CB  1 
ATOM   10353 C  CG  . ASP F 1 49  ? 78.929  76.572  36.818  1.00 34.38  ? 49  ASP F CG  1 
ATOM   10354 O  OD1 . ASP F 1 49  ? 78.586  77.764  37.009  1.00 33.14  ? 49  ASP F OD1 1 
ATOM   10355 O  OD2 . ASP F 1 49  ? 78.600  75.645  37.598  1.00 32.63  ? 49  ASP F OD2 1 
ATOM   10356 N  N   . GLY F 1 50  ? 81.043  76.008  32.877  1.00 41.24  ? 50  GLY F N   1 
ATOM   10357 C  CA  . GLY F 1 50  ? 82.121  75.800  31.925  1.00 40.77  ? 50  GLY F CA  1 
ATOM   10358 C  C   . GLY F 1 50  ? 83.387  75.176  32.473  1.00 39.62  ? 50  GLY F C   1 
ATOM   10359 O  O   . GLY F 1 50  ? 84.449  75.343  31.864  1.00 45.71  ? 50  GLY F O   1 
ATOM   10360 N  N   . GLY F 1 51  ? 83.316  74.460  33.596  1.00 39.54  ? 51  GLY F N   1 
ATOM   10361 C  CA  . GLY F 1 51  ? 84.457  73.759  34.165  1.00 38.17  ? 51  GLY F CA  1 
ATOM   10362 C  C   . GLY F 1 51  ? 85.617  74.686  34.491  1.00 41.74  ? 51  GLY F C   1 
ATOM   10363 O  O   . GLY F 1 51  ? 85.461  75.900  34.661  1.00 42.15  ? 51  GLY F O   1 
ATOM   10364 N  N   . CYS F 1 52  ? 86.805  74.086  34.568  1.00 41.59  ? 52  CYS F N   1 
ATOM   10365 C  CA  . CYS F 1 52  ? 88.024  74.844  34.836  1.00 41.06  ? 52  CYS F CA  1 
ATOM   10366 C  C   . CYS F 1 52  ? 88.469  75.614  33.594  1.00 43.07  ? 52  CYS F C   1 
ATOM   10367 O  O   . CYS F 1 52  ? 88.218  75.206  32.454  1.00 43.78  ? 52  CYS F O   1 
ATOM   10368 C  CB  . CYS F 1 52  ? 89.158  73.922  35.305  1.00 38.76  ? 52  CYS F CB  1 
ATOM   10369 S  SG  . CYS F 1 52  ? 88.715  72.682  36.577  1.00 39.79  ? 52  CYS F SG  1 
ATOM   10370 N  N   . ALA F 1 53  ? 89.136  76.742  33.829  1.00 43.17  ? 53  ALA F N   1 
ATOM   10371 C  CA  . ALA F 1 53  ? 89.660  77.547  32.733  1.00 47.25  ? 53  ALA F CA  1 
ATOM   10372 C  C   . ALA F 1 53  ? 90.611  76.723  31.866  1.00 48.93  ? 53  ALA F C   1 
ATOM   10373 O  O   . ALA F 1 53  ? 91.320  75.836  32.354  1.00 43.35  ? 53  ALA F O   1 
ATOM   10374 C  CB  . ALA F 1 53  ? 90.384  78.774  33.285  1.00 43.07  ? 53  ALA F CB  1 
ATOM   10375 N  N   . VAL F 1 54  ? 90.628  77.023  30.561  1.00 48.05  ? 54  VAL F N   1 
ATOM   10376 C  CA  . VAL F 1 54  ? 91.479  76.247  29.661  1.00 51.79  ? 54  VAL F CA  1 
ATOM   10377 C  C   . VAL F 1 54  ? 92.948  76.451  30.010  1.00 53.03  ? 54  VAL F C   1 
ATOM   10378 O  O   . VAL F 1 54  ? 93.754  75.519  29.895  1.00 57.12  ? 54  VAL F O   1 
ATOM   10379 C  CB  . VAL F 1 54  ? 91.182  76.580  28.182  1.00 52.29  ? 54  VAL F CB  1 
ATOM   10380 C  CG1 . VAL F 1 54  ? 91.503  78.038  27.856  1.00 51.51  ? 54  VAL F CG1 1 
ATOM   10381 C  CG2 . VAL F 1 54  ? 91.930  75.628  27.268  1.00 49.36  ? 54  VAL F CG2 1 
ATOM   10382 N  N   . GLU F 1 55  ? 93.307  77.643  30.501  1.00 49.85  ? 55  GLU F N   1 
ATOM   10383 C  CA  . GLU F 1 55  ? 94.657  77.924  30.988  1.00 51.39  ? 55  GLU F CA  1 
ATOM   10384 C  C   . GLU F 1 55  ? 95.163  76.886  31.990  1.00 57.51  ? 55  GLU F C   1 
ATOM   10385 O  O   . GLU F 1 55  ? 96.382  76.751  32.165  1.00 60.74  ? 55  GLU F O   1 
ATOM   10386 C  CB  . GLU F 1 55  ? 94.684  79.315  31.635  1.00 48.36  ? 55  GLU F CB  1 
ATOM   10387 C  CG  . GLU F 1 55  ? 94.599  80.487  30.656  1.00 51.98  ? 55  GLU F CG  1 
ATOM   10388 C  CD  . GLU F 1 55  ? 93.183  80.734  30.142  1.00 52.31  ? 55  GLU F CD  1 
ATOM   10389 O  OE1 . GLU F 1 55  ? 92.266  79.963  30.505  1.00 49.23  ? 55  GLU F OE1 1 
ATOM   10390 O  OE2 . GLU F 1 55  ? 92.985  81.709  29.381  1.00 57.51  ? 55  GLU F OE2 1 
ATOM   10391 N  N   . CYS F 1 56  ? 94.260  76.156  32.658  1.00 54.23  ? 56  CYS F N   1 
ATOM   10392 C  CA  . CYS F 1 56  ? 94.679  75.127  33.608  1.00 55.33  ? 56  CYS F CA  1 
ATOM   10393 C  C   . CYS F 1 56  ? 95.303  73.927  32.915  1.00 57.92  ? 56  CYS F C   1 
ATOM   10394 O  O   . CYS F 1 56  ? 96.094  73.200  33.528  1.00 61.20  ? 56  CYS F O   1 
ATOM   10395 C  CB  . CYS F 1 56  ? 93.491  74.654  34.442  1.00 53.99  ? 56  CYS F CB  1 
ATOM   10396 S  SG  . CYS F 1 56  ? 92.886  75.880  35.598  1.00 57.13  ? 56  CYS F SG  1 
ATOM   10397 N  N   . ALA F 1 57  ? 94.935  73.676  31.659  1.00 58.34  ? 57  ALA F N   1 
ATOM   10398 C  CA  . ALA F 1 57  ? 95.546  72.570  30.935  1.00 60.15  ? 57  ALA F CA  1 
ATOM   10399 C  C   . ALA F 1 57  ? 97.016  72.854  30.652  1.00 62.29  ? 57  ALA F C   1 
ATOM   10400 O  O   . ALA F 1 57  ? 97.854  71.946  30.718  1.00 57.81  ? 57  ALA F O   1 
ATOM   10401 C  CB  . ALA F 1 57  ? 94.781  72.309  29.638  1.00 60.21  ? 57  ALA F CB  1 
ATOM   10402 N  N   . SER F 1 58  ? 97.346  74.112  30.357  1.00 60.01  ? 58  SER F N   1 
ATOM   10403 C  CA  . SER F 1 58  ? 98.734  74.500  30.106  1.00 61.61  ? 58  SER F CA  1 
ATOM   10404 C  C   . SER F 1 58  ? 99.502  74.706  31.411  1.00 67.94  ? 58  SER F C   1 
ATOM   10405 O  O   . SER F 1 58  ? 100.413 73.937  31.736  1.00 67.74  ? 58  SER F O   1 
ATOM   10406 C  CB  . SER F 1 58  ? 98.776  75.772  29.252  1.00 61.97  ? 58  SER F CB  1 
ATOM   10407 O  OG  . SER F 1 58  ? 97.848  75.713  28.180  1.00 65.10  ? 58  SER F OG  1 
ATOM   10408 N  N   . ASP F 1 59  ? 99.134  75.736  32.179  1.00 64.55  ? 59  ASP F N   1 
ATOM   10409 C  CA  . ASP F 1 59  ? 99.952  76.234  33.288  1.00 61.12  ? 59  ASP F CA  1 
ATOM   10410 C  C   . ASP F 1 59  ? 99.118  76.394  34.559  1.00 59.79  ? 59  ASP F C   1 
ATOM   10411 O  O   . ASP F 1 59  ? 98.806  77.517  34.976  1.00 56.07  ? 59  ASP F O   1 
ATOM   10412 C  CB  . ASP F 1 59  ? 100.604 77.559  32.890  1.00 59.85  ? 59  ASP F CB  1 
ATOM   10413 C  CG  . ASP F 1 59  ? 101.538 78.095  33.948  1.00 59.62  ? 59  ASP F CG  1 
ATOM   10414 O  OD1 . ASP F 1 59  ? 101.953 77.312  34.838  1.00 57.39  ? 59  ASP F OD1 1 
ATOM   10415 O  OD2 . ASP F 1 59  ? 101.846 79.309  33.887  1.00 57.25  ? 59  ASP F OD2 1 
ATOM   10416 N  N   . PRO F 1 60  ? 98.769  75.278  35.223  1.00 55.65  ? 60  PRO F N   1 
ATOM   10417 C  CA  . PRO F 1 60  ? 97.967  75.359  36.454  1.00 56.59  ? 60  PRO F CA  1 
ATOM   10418 C  C   . PRO F 1 60  ? 98.507  76.319  37.506  1.00 57.13  ? 60  PRO F C   1 
ATOM   10419 O  O   . PRO F 1 60  ? 97.785  77.223  37.947  1.00 52.41  ? 60  PRO F O   1 
ATOM   10420 C  CB  . PRO F 1 60  ? 97.984  73.918  36.978  1.00 55.64  ? 60  PRO F CB  1 
ATOM   10421 C  CG  . PRO F 1 60  ? 98.250  73.072  35.802  1.00 58.65  ? 60  PRO F CG  1 
ATOM   10422 C  CD  . PRO F 1 60  ? 99.000  73.891  34.790  1.00 57.63  ? 60  PRO F CD  1 
ATOM   10423 N  N   . LYS F 1 61  ? 99.761  76.125  37.929  1.00 54.06  ? 61  LYS F N   1 
ATOM   10424 C  CA  . LYS F 1 61  ? 100.323 76.971  38.980  1.00 52.72  ? 61  LYS F CA  1 
ATOM   10425 C  C   . LYS F 1 61  ? 100.307 78.436  38.570  1.00 50.96  ? 61  LYS F C   1 
ATOM   10426 O  O   . LYS F 1 61  ? 100.116 79.322  39.410  1.00 48.29  ? 61  LYS F O   1 
ATOM   10427 C  CB  . LYS F 1 61  ? 101.754 76.538  39.321  1.00 58.93  ? 61  LYS F CB  1 
ATOM   10428 C  CG  . LYS F 1 61  ? 102.007 75.038  39.282  1.00 61.32  ? 61  LYS F CG  1 
ATOM   10429 C  CD  . LYS F 1 61  ? 103.505 74.749  39.102  1.00 73.72  ? 61  LYS F CD  1 
ATOM   10430 C  CE  . LYS F 1 61  ? 103.767 73.415  38.392  1.00 70.46  ? 61  LYS F CE  1 
ATOM   10431 N  NZ  . LYS F 1 61  ? 104.504 72.430  39.242  1.00 76.27  ? 61  LYS F NZ  1 
ATOM   10432 N  N   . GLY F 1 62  ? 100.501 78.712  37.281  1.00 51.54  ? 62  GLY F N   1 
ATOM   10433 C  CA  . GLY F 1 62  ? 100.577 80.094  36.840  1.00 53.64  ? 62  GLY F CA  1 
ATOM   10434 C  C   . GLY F 1 62  ? 99.234  80.796  36.799  1.00 53.76  ? 62  GLY F C   1 
ATOM   10435 O  O   . GLY F 1 62  ? 99.162  82.016  36.975  1.00 59.14  ? 62  GLY F O   1 
ATOM   10436 N  N   . TYR F 1 63  ? 98.157  80.053  36.556  1.00 51.49  ? 63  TYR F N   1 
ATOM   10437 C  CA  . TYR F 1 63  ? 96.836  80.660  36.439  1.00 49.75  ? 63  TYR F CA  1 
ATOM   10438 C  C   . TYR F 1 63  ? 96.057  80.633  37.746  1.00 49.44  ? 63  TYR F C   1 
ATOM   10439 O  O   . TYR F 1 63  ? 95.456  81.644  38.114  1.00 47.12  ? 63  TYR F O   1 
ATOM   10440 C  CB  . TYR F 1 63  ? 96.021  79.963  35.346  1.00 48.09  ? 63  TYR F CB  1 
ATOM   10441 C  CG  . TYR F 1 63  ? 94.835  80.776  34.861  1.00 46.12  ? 63  TYR F CG  1 
ATOM   10442 C  CD1 . TYR F 1 63  ? 95.022  81.928  34.108  1.00 45.81  ? 63  TYR F CD1 1 
ATOM   10443 C  CD2 . TYR F 1 63  ? 93.532  80.387  35.153  1.00 44.77  ? 63  TYR F CD2 1 
ATOM   10444 C  CE1 . TYR F 1 63  ? 93.941  82.674  33.656  1.00 46.65  ? 63  TYR F CE1 1 
ATOM   10445 C  CE2 . TYR F 1 63  ? 92.440  81.124  34.704  1.00 44.51  ? 63  TYR F CE2 1 
ATOM   10446 C  CZ  . TYR F 1 63  ? 92.651  82.267  33.958  1.00 47.59  ? 63  TYR F CZ  1 
ATOM   10447 O  OH  . TYR F 1 63  ? 91.576  83.004  33.512  1.00 45.82  ? 63  TYR F OH  1 
ATOM   10448 N  N   . TRP F 1 64  ? 96.067  79.506  38.463  1.00 45.98  ? 64  TRP F N   1 
ATOM   10449 C  CA  . TRP F 1 64  ? 95.360  79.391  39.733  1.00 43.85  ? 64  TRP F CA  1 
ATOM   10450 C  C   . TRP F 1 64  ? 96.186  79.851  40.930  1.00 49.95  ? 64  TRP F C   1 
ATOM   10451 O  O   . TRP F 1 64  ? 95.615  80.361  41.899  1.00 48.85  ? 64  TRP F O   1 
ATOM   10452 C  CB  . TRP F 1 64  ? 94.915  77.946  39.968  1.00 38.04  ? 64  TRP F CB  1 
ATOM   10453 C  CG  . TRP F 1 64  ? 93.648  77.578  39.269  1.00 36.74  ? 64  TRP F CG  1 
ATOM   10454 C  CD1 . TRP F 1 64  ? 92.962  78.332  38.362  1.00 36.78  ? 64  TRP F CD1 1 
ATOM   10455 C  CD2 . TRP F 1 64  ? 92.923  76.348  39.396  1.00 35.89  ? 64  TRP F CD2 1 
ATOM   10456 N  NE1 . TRP F 1 64  ? 91.850  77.652  37.920  1.00 34.66  ? 64  TRP F NE1 1 
ATOM   10457 C  CE2 . TRP F 1 64  ? 91.805  76.431  38.544  1.00 37.65  ? 64  TRP F CE2 1 
ATOM   10458 C  CE3 . TRP F 1 64  ? 93.105  75.189  40.154  1.00 39.79  ? 64  TRP F CE3 1 
ATOM   10459 C  CZ2 . TRP F 1 64  ? 90.878  75.402  38.431  1.00 35.35  ? 64  TRP F CZ2 1 
ATOM   10460 C  CZ3 . TRP F 1 64  ? 92.182  74.172  40.039  1.00 39.57  ? 64  TRP F CZ3 1 
ATOM   10461 C  CH2 . TRP F 1 64  ? 91.084  74.283  39.185  1.00 37.80  ? 64  TRP F CH2 1 
ATOM   10462 N  N   . GLY F 1 65  ? 97.505  79.663  40.913  1.00 51.05  ? 65  GLY F N   1 
ATOM   10463 C  CA  . GLY F 1 65  ? 98.309  80.066  42.052  1.00 42.57  ? 65  GLY F CA  1 
ATOM   10464 C  C   . GLY F 1 65  ? 98.422  78.980  43.100  1.00 47.05  ? 65  GLY F C   1 
ATOM   10465 O  O   . GLY F 1 65  ? 98.324  77.791  42.774  1.00 47.29  ? 65  GLY F O   1 
ATOM   10466 N  N   . ASP F 1 66  ? 98.605  79.380  44.367  1.00 45.87  ? 66  ASP F N   1 
ATOM   10467 C  CA  . ASP F 1 66  ? 98.896  78.421  45.437  1.00 46.53  ? 66  ASP F CA  1 
ATOM   10468 C  C   . ASP F 1 66  ? 97.793  77.387  45.620  1.00 45.76  ? 66  ASP F C   1 
ATOM   10469 O  O   . ASP F 1 66  ? 98.053  76.290  46.134  1.00 44.98  ? 66  ASP F O   1 
ATOM   10470 C  CB  . ASP F 1 66  ? 99.118  79.150  46.763  1.00 54.14  ? 66  ASP F CB  1 
ATOM   10471 C  CG  . ASP F 1 66  ? 100.357 80.025  46.759  1.00 57.06  ? 66  ASP F CG  1 
ATOM   10472 O  OD1 . ASP F 1 66  ? 101.120 79.997  45.767  1.00 52.73  ? 66  ASP F OD1 1 
ATOM   10473 O  OD2 . ASP F 1 66  ? 100.564 80.751  47.759  1.00 59.29  ? 66  ASP F OD2 1 
ATOM   10474 N  N   . ILE F 1 67  ? 96.562  77.710  45.214  1.00 45.21  ? 67  ILE F N   1 
ATOM   10475 C  CA  . ILE F 1 67  ? 95.439  76.817  45.484  1.00 46.70  ? 67  ILE F CA  1 
ATOM   10476 C  C   . ILE F 1 67  ? 95.635  75.456  44.814  1.00 45.76  ? 67  ILE F C   1 
ATOM   10477 O  O   . ILE F 1 67  ? 95.058  74.453  45.260  1.00 42.10  ? 67  ILE F O   1 
ATOM   10478 C  CB  . ILE F 1 67  ? 94.113  77.509  45.066  1.00 42.33  ? 67  ILE F CB  1 
ATOM   10479 C  CG1 . ILE F 1 67  ? 92.890  76.688  45.491  1.00 41.19  ? 67  ILE F CG1 1 
ATOM   10480 C  CG2 . ILE F 1 67  ? 94.090  77.820  43.574  1.00 42.66  ? 67  ILE F CG2 1 
ATOM   10481 C  CD1 . ILE F 1 67  ? 92.709  76.597  46.989  1.00 40.73  ? 67  ILE F CD1 1 
ATOM   10482 N  N   . THR F 1 68  ? 96.473  75.388  43.771  1.00 44.94  ? 68  THR F N   1 
ATOM   10483 C  CA  . THR F 1 68  ? 96.811  74.105  43.153  1.00 49.00  ? 68  THR F CA  1 
ATOM   10484 C  C   . THR F 1 68  ? 97.489  73.143  44.128  1.00 48.19  ? 68  THR F C   1 
ATOM   10485 O  O   . THR F 1 68  ? 97.628  71.958  43.803  1.00 53.10  ? 68  THR F O   1 
ATOM   10486 C  CB  . THR F 1 68  ? 97.713  74.315  41.923  1.00 47.06  ? 68  THR F CB  1 
ATOM   10487 O  OG1 . THR F 1 68  ? 98.923  74.975  42.312  1.00 46.55  ? 68  THR F OG1 1 
ATOM   10488 C  CG2 . THR F 1 68  ? 97.008  75.162  40.869  1.00 43.28  ? 68  THR F CG2 1 
ATOM   10489 N  N   . SER F 1 69  ? 97.909  73.613  45.308  1.00 47.10  ? 69  SER F N   1 
ATOM   10490 C  CA  . SER F 1 69  ? 98.390  72.696  46.335  1.00 46.01  ? 69  SER F CA  1 
ATOM   10491 C  C   . SER F 1 69  ? 97.260  71.925  47.004  1.00 44.92  ? 69  SER F C   1 
ATOM   10492 O  O   . SER F 1 69  ? 97.532  70.934  47.687  1.00 49.41  ? 69  SER F O   1 
ATOM   10493 C  CB  . SER F 1 69  ? 99.187  73.452  47.404  1.00 49.28  ? 69  SER F CB  1 
ATOM   10494 O  OG  . SER F 1 69  ? 98.360  74.342  48.138  1.00 49.37  ? 69  SER F OG  1 
ATOM   10495 N  N   . VAL F 1 70  ? 96.006  72.349  46.835  1.00 46.53  ? 70  VAL F N   1 
ATOM   10496 C  CA  . VAL F 1 70  ? 94.857  71.645  47.391  1.00 47.20  ? 70  VAL F CA  1 
ATOM   10497 C  C   . VAL F 1 70  ? 94.061  70.925  46.310  1.00 43.99  ? 70  VAL F C   1 
ATOM   10498 O  O   . VAL F 1 70  ? 93.577  69.813  46.529  1.00 42.50  ? 70  VAL F O   1 
ATOM   10499 C  CB  . VAL F 1 70  ? 93.942  72.603  48.190  1.00 46.64  ? 70  VAL F CB  1 
ATOM   10500 C  CG1 . VAL F 1 70  ? 92.991  71.805  49.094  1.00 47.15  ? 70  VAL F CG1 1 
ATOM   10501 C  CG2 . VAL F 1 70  ? 94.765  73.609  48.992  1.00 44.57  ? 70  VAL F CG2 1 
ATOM   10502 N  N   . TYR F 1 71  ? 93.894  71.551  45.151  1.00 43.42  ? 71  TYR F N   1 
ATOM   10503 C  CA  . TYR F 1 71  ? 93.138  70.986  44.036  1.00 46.51  ? 71  TYR F CA  1 
ATOM   10504 C  C   . TYR F 1 71  ? 94.031  71.039  42.806  1.00 45.42  ? 71  TYR F C   1 
ATOM   10505 O  O   . TYR F 1 71  ? 94.290  72.125  42.281  1.00 47.28  ? 71  TYR F O   1 
ATOM   10506 C  CB  . TYR F 1 71  ? 91.853  71.775  43.770  1.00 50.10  ? 71  TYR F CB  1 
ATOM   10507 C  CG  . TYR F 1 71  ? 90.891  71.909  44.932  1.00 49.25  ? 71  TYR F CG  1 
ATOM   10508 C  CD1 . TYR F 1 71  ? 90.048  70.863  45.288  1.00 48.66  ? 71  TYR F CD1 1 
ATOM   10509 C  CD2 . TYR F 1 71  ? 90.811  73.094  45.656  1.00 46.78  ? 71  TYR F CD2 1 
ATOM   10510 C  CE1 . TYR F 1 71  ? 89.155  70.990  46.338  1.00 49.14  ? 71  TYR F CE1 1 
ATOM   10511 C  CE2 . TYR F 1 71  ? 89.928  73.231  46.708  1.00 48.61  ? 71  TYR F CE2 1 
ATOM   10512 C  CZ  . TYR F 1 71  ? 89.101  72.178  47.044  1.00 51.18  ? 71  TYR F CZ  1 
ATOM   10513 O  OH  . TYR F 1 71  ? 88.229  72.320  48.095  1.00 49.83  ? 71  TYR F OH  1 
ATOM   10514 N  N   . TRP F 1 72  ? 94.509  69.887  42.336  1.00 49.02  ? 72  TRP F N   1 
ATOM   10515 C  CA  . TRP F 1 72  ? 95.320  69.883  41.123  1.00 48.58  ? 72  TRP F CA  1 
ATOM   10516 C  C   . TRP F 1 72  ? 94.443  69.569  39.918  1.00 42.06  ? 72  TRP F C   1 
ATOM   10517 O  O   . TRP F 1 72  ? 93.825  68.499  39.881  1.00 44.53  ? 72  TRP F O   1 
ATOM   10518 C  CB  . TRP F 1 72  ? 96.465  68.886  41.211  1.00 51.54  ? 72  TRP F CB  1 
ATOM   10519 C  CG  . TRP F 1 72  ? 97.319  68.987  39.981  1.00 56.25  ? 72  TRP F CG  1 
ATOM   10520 C  CD1 . TRP F 1 72  ? 97.162  68.290  38.812  1.00 57.37  ? 72  TRP F CD1 1 
ATOM   10521 C  CD2 . TRP F 1 72  ? 98.401  69.903  39.758  1.00 57.48  ? 72  TRP F CD2 1 
ATOM   10522 N  NE1 . TRP F 1 72  ? 98.099  68.695  37.892  1.00 61.84  ? 72  TRP F NE1 1 
ATOM   10523 C  CE2 . TRP F 1 72  ? 98.872  69.684  38.446  1.00 60.68  ? 72  TRP F CE2 1 
ATOM   10524 C  CE3 . TRP F 1 72  ? 99.033  70.873  40.548  1.00 55.68  ? 72  TRP F CE3 1 
ATOM   10525 C  CZ2 . TRP F 1 72  ? 99.946  70.399  37.905  1.00 58.18  ? 72  TRP F CZ2 1 
ATOM   10526 C  CZ3 . TRP F 1 72  ? 100.098 71.582  40.006  1.00 58.44  ? 72  TRP F CZ3 1 
ATOM   10527 C  CH2 . TRP F 1 72  ? 100.541 71.340  38.698  1.00 58.22  ? 72  TRP F CH2 1 
ATOM   10528 N  N   . PRO F 1 73  ? 94.357  70.455  38.925  1.00 43.70  ? 73  PRO F N   1 
ATOM   10529 C  CA  . PRO F 1 73  ? 93.538  70.172  37.737  1.00 45.44  ? 73  PRO F CA  1 
ATOM   10530 C  C   . PRO F 1 73  ? 94.299  69.324  36.720  1.00 52.82  ? 73  PRO F C   1 
ATOM   10531 O  O   . PRO F 1 73  ? 95.420  69.657  36.321  1.00 49.09  ? 73  PRO F O   1 
ATOM   10532 C  CB  . PRO F 1 73  ? 93.236  71.565  37.182  1.00 40.90  ? 73  PRO F CB  1 
ATOM   10533 C  CG  . PRO F 1 73  ? 94.441  72.370  37.578  1.00 42.44  ? 73  PRO F CG  1 
ATOM   10534 C  CD  . PRO F 1 73  ? 94.971  71.791  38.866  1.00 43.89  ? 73  PRO F CD  1 
ATOM   10535 N  N   . VAL F 1 74  ? 93.685  68.217  36.309  1.00 52.83  ? 74  VAL F N   1 
ATOM   10536 C  CA  . VAL F 1 74  ? 94.226  67.333  35.280  1.00 51.12  ? 74  VAL F CA  1 
ATOM   10537 C  C   . VAL F 1 74  ? 93.305  67.434  34.076  1.00 48.60  ? 74  VAL F C   1 
ATOM   10538 O  O   . VAL F 1 74  ? 92.204  66.872  34.085  1.00 50.59  ? 74  VAL F O   1 
ATOM   10539 C  CB  . VAL F 1 74  ? 94.333  65.881  35.767  1.00 54.00  ? 74  VAL F CB  1 
ATOM   10540 C  CG1 . VAL F 1 74  ? 95.094  65.017  34.755  1.00 48.18  ? 74  VAL F CG1 1 
ATOM   10541 C  CG2 . VAL F 1 74  ? 94.983  65.830  37.138  1.00 55.64  ? 74  VAL F CG2 1 
ATOM   10542 N  N   . MET F 1 75  ? 93.735  68.139  33.036  1.00 49.41  ? 75  MET F N   1 
ATOM   10543 C  CA  . MET F 1 75  ? 92.844  68.281  31.896  1.00 56.58  ? 75  MET F CA  1 
ATOM   10544 C  C   . MET F 1 75  ? 93.653  68.653  30.664  1.00 56.87  ? 75  MET F C   1 
ATOM   10545 O  O   . MET F 1 75  ? 94.786  69.130  30.763  1.00 57.78  ? 75  MET F O   1 
ATOM   10546 C  CB  . MET F 1 75  ? 91.742  69.314  32.180  1.00 55.58  ? 75  MET F CB  1 
ATOM   10547 C  CG  . MET F 1 75  ? 91.989  70.709  31.623  1.00 56.73  ? 75  MET F CG  1 
ATOM   10548 S  SD  . MET F 1 75  ? 90.797  71.937  32.213  1.00 54.00  ? 75  MET F SD  1 
ATOM   10549 C  CE  . MET F 1 75  ? 90.838  73.096  30.861  1.00 49.27  ? 75  MET F CE  1 
ATOM   10550 N  N   . ARG F 1 76  ? 93.049  68.425  29.499  1.00 56.53  ? 76  ARG F N   1 
ATOM   10551 C  CA  . ARG F 1 76  ? 93.683  68.677  28.213  1.00 58.07  ? 76  ARG F CA  1 
ATOM   10552 C  C   . ARG F 1 76  ? 93.050  69.891  27.539  1.00 60.27  ? 76  ARG F C   1 
ATOM   10553 O  O   . ARG F 1 76  ? 91.870  70.190  27.746  1.00 61.51  ? 76  ARG F O   1 
ATOM   10554 C  CB  . ARG F 1 76  ? 93.568  67.436  27.325  1.00 63.71  ? 76  ARG F CB  1 
ATOM   10555 C  CG  . ARG F 1 76  ? 93.607  66.139  28.134  1.00 62.80  ? 76  ARG F CG  1 
ATOM   10556 C  CD  . ARG F 1 76  ? 93.450  64.915  27.267  1.00 64.58  ? 76  ARG F CD  1 
ATOM   10557 N  NE  . ARG F 1 76  ? 92.139  64.880  26.629  1.00 66.53  ? 76  ARG F NE  1 
ATOM   10558 C  CZ  . ARG F 1 76  ? 91.067  64.291  27.143  1.00 63.49  ? 76  ARG F CZ  1 
ATOM   10559 N  NH1 . ARG F 1 76  ? 91.121  63.643  28.297  1.00 64.44  ? 76  ARG F NH1 1 
ATOM   10560 N  NH2 . ARG F 1 76  ? 89.915  64.349  26.481  1.00 63.22  ? 76  ARG F NH2 1 
ATOM   10561 N  N   . ILE F 1 77  ? 93.850  70.591  26.724  1.00 56.33  ? 77  ILE F N   1 
ATOM   10562 C  CA  . ILE F 1 77  ? 93.410  71.848  26.116  1.00 61.00  ? 77  ILE F CA  1 
ATOM   10563 C  C   . ILE F 1 77  ? 92.138  71.667  25.295  1.00 60.24  ? 77  ILE F C   1 
ATOM   10564 O  O   . ILE F 1 77  ? 91.334  72.598  25.173  1.00 60.78  ? 77  ILE F O   1 
ATOM   10565 C  CB  . ILE F 1 77  ? 94.552  72.457  25.272  1.00 65.68  ? 77  ILE F CB  1 
ATOM   10566 C  CG1 . ILE F 1 77  ? 95.746  72.806  26.165  1.00 65.34  ? 77  ILE F CG1 1 
ATOM   10567 C  CG2 . ILE F 1 77  ? 94.088  73.698  24.501  1.00 61.11  ? 77  ILE F CG2 1 
ATOM   10568 C  CD1 . ILE F 1 77  ? 97.068  72.833  25.436  1.00 67.71  ? 77  ILE F CD1 1 
ATOM   10569 N  N   . GLU F 1 78  ? 91.920  70.478  24.733  1.00 64.03  ? 78  GLU F N   1 
ATOM   10570 C  CA  . GLU F 1 78  ? 90.686  70.237  23.994  1.00 63.39  ? 78  GLU F CA  1 
ATOM   10571 C  C   . GLU F 1 78  ? 89.477  70.066  24.909  1.00 60.16  ? 78  GLU F C   1 
ATOM   10572 O  O   . GLU F 1 78  ? 88.353  69.960  24.407  1.00 58.25  ? 78  GLU F O   1 
ATOM   10573 C  CB  . GLU F 1 78  ? 90.841  69.007  23.093  1.00 62.47  ? 78  GLU F CB  1 
ATOM   10574 C  CG  . GLU F 1 78  ? 90.872  67.675  23.833  1.00 66.20  ? 78  GLU F CG  1 
ATOM   10575 C  CD  . GLU F 1 78  ? 92.280  67.114  23.987  1.00 72.87  ? 78  GLU F CD  1 
ATOM   10576 O  OE1 . GLU F 1 78  ? 93.251  67.768  23.537  1.00 70.31  ? 78  GLU F OE1 1 
ATOM   10577 O  OE2 . GLU F 1 78  ? 92.412  66.006  24.551  1.00 75.84  ? 78  GLU F OE2 1 
ATOM   10578 N  N   . GLU F 1 79  ? 89.676  70.029  26.229  1.00 57.93  ? 79  GLU F N   1 
ATOM   10579 C  CA  . GLU F 1 79  ? 88.563  70.010  27.166  1.00 57.76  ? 79  GLU F CA  1 
ATOM   10580 C  C   . GLU F 1 79  ? 88.104  71.408  27.570  1.00 55.88  ? 79  GLU F C   1 
ATOM   10581 O  O   . GLU F 1 79  ? 87.029  71.537  28.163  1.00 51.89  ? 79  GLU F O   1 
ATOM   10582 C  CB  . GLU F 1 79  ? 88.935  69.212  28.415  1.00 55.13  ? 79  GLU F CB  1 
ATOM   10583 C  CG  . GLU F 1 79  ? 89.525  67.845  28.126  1.00 57.12  ? 79  GLU F CG  1 
ATOM   10584 C  CD  . GLU F 1 79  ? 89.564  66.960  29.353  1.00 54.61  ? 79  GLU F CD  1 
ATOM   10585 O  OE1 . GLU F 1 79  ? 88.491  66.454  29.747  1.00 51.94  ? 79  GLU F OE1 1 
ATOM   10586 O  OE2 . GLU F 1 79  ? 90.665  66.768  29.919  1.00 53.92  ? 79  GLU F OE2 1 
ATOM   10587 N  N   . GLY F 1 80  ? 88.891  72.446  27.275  1.00 55.08  ? 80  GLY F N   1 
ATOM   10588 C  CA  . GLY F 1 80  ? 88.448  73.823  27.426  1.00 55.67  ? 80  GLY F CA  1 
ATOM   10589 C  C   . GLY F 1 80  ? 87.077  74.029  26.813  1.00 55.03  ? 80  GLY F C   1 
ATOM   10590 O  O   . GLY F 1 80  ? 86.810  73.516  25.720  1.00 52.97  ? 80  GLY F O   1 
ATOM   10591 N  N   . CYS F 1 81  ? 86.196  74.765  27.506  1.00 49.99  ? 81  CYS F N   1 
ATOM   10592 C  CA  . CYS F 1 81  ? 84.784  74.761  27.129  1.00 50.06  ? 81  CYS F CA  1 
ATOM   10593 C  C   . CYS F 1 81  ? 84.564  75.370  25.751  1.00 44.26  ? 81  CYS F C   1 
ATOM   10594 O  O   . CYS F 1 81  ? 83.646  74.957  25.038  1.00 47.83  ? 81  CYS F O   1 
ATOM   10595 C  CB  . CYS F 1 81  ? 83.932  75.483  28.189  1.00 47.55  ? 81  CYS F CB  1 
ATOM   10596 S  SG  . CYS F 1 81  ? 84.384  77.209  28.587  1.00 49.84  ? 81  CYS F SG  1 
ATOM   10597 N  N   . VAL F 1 82  ? 85.392  76.338  25.353  1.00 47.92  ? 82  VAL F N   1 
ATOM   10598 C  CA  . VAL F 1 82  ? 85.256  76.915  24.016  1.00 54.33  ? 82  VAL F CA  1 
ATOM   10599 C  C   . VAL F 1 82  ? 85.694  75.918  22.952  1.00 54.73  ? 82  VAL F C   1 
ATOM   10600 O  O   . VAL F 1 82  ? 85.128  75.875  21.849  1.00 51.38  ? 82  VAL F O   1 
ATOM   10601 C  CB  . VAL F 1 82  ? 86.058  78.223  23.916  1.00 53.14  ? 82  VAL F CB  1 
ATOM   10602 C  CG1 . VAL F 1 82  ? 86.131  78.687  22.465  1.00 45.28  ? 82  VAL F CG1 1 
ATOM   10603 C  CG2 . VAL F 1 82  ? 85.432  79.288  24.808  1.00 43.72  ? 82  VAL F CG2 1 
ATOM   10604 N  N   . GLN F 1 83  ? 86.690  75.095  23.268  1.00 51.18  ? 83  GLN F N   1 
ATOM   10605 C  CA  . GLN F 1 83  ? 87.197  74.124  22.311  1.00 53.90  ? 83  GLN F CA  1 
ATOM   10606 C  C   . GLN F 1 83  ? 86.280  72.909  22.203  1.00 57.36  ? 83  GLN F C   1 
ATOM   10607 O  O   . GLN F 1 83  ? 86.002  72.436  21.095  1.00 58.04  ? 83  GLN F O   1 
ATOM   10608 C  CB  . GLN F 1 83  ? 88.618  73.723  22.709  1.00 55.12  ? 83  GLN F CB  1 
ATOM   10609 C  CG  . GLN F 1 83  ? 89.640  74.868  22.595  1.00 58.13  ? 83  GLN F CG  1 
ATOM   10610 C  CD  . GLN F 1 83  ? 89.657  75.825  23.800  1.00 59.60  ? 83  GLN F CD  1 
ATOM   10611 O  OE1 . GLN F 1 83  ? 88.667  75.968  24.530  1.00 51.11  ? 83  GLN F OE1 1 
ATOM   10612 N  NE2 . GLN F 1 83  ? 90.799  76.481  24.007  1.00 55.81  ? 83  GLN F NE2 1 
ATOM   10613 N  N   . ALA F 1 84  ? 85.785  72.397  23.333  1.00 49.90  ? 84  ALA F N   1 
ATOM   10614 C  CA  . ALA F 1 84  ? 84.883  71.253  23.268  1.00 55.18  ? 84  ALA F CA  1 
ATOM   10615 C  C   . ALA F 1 84  ? 83.559  71.619  22.609  1.00 56.10  ? 84  ALA F C   1 
ATOM   10616 O  O   . ALA F 1 84  ? 82.926  70.764  21.981  1.00 58.51  ? 84  ALA F O   1 
ATOM   10617 C  CB  . ALA F 1 84  ? 84.641  70.682  24.664  1.00 51.32  ? 84  ALA F CB  1 
ATOM   10618 N  N   . LEU F 1 85  ? 83.120  72.871  22.749  1.00 56.54  ? 85  LEU F N   1 
ATOM   10619 C  CA  . LEU F 1 85  ? 81.939  73.320  22.022  1.00 61.01  ? 85  LEU F CA  1 
ATOM   10620 C  C   . LEU F 1 85  ? 82.251  73.541  20.551  1.00 61.13  ? 85  LEU F C   1 
ATOM   10621 O  O   . LEU F 1 85  ? 81.383  73.320  19.698  1.00 64.02  ? 85  LEU F O   1 
ATOM   10622 C  CB  . LEU F 1 85  ? 81.380  74.613  22.629  1.00 54.82  ? 85  LEU F CB  1 
ATOM   10623 C  CG  . LEU F 1 85  ? 80.516  74.542  23.895  1.00 48.10  ? 85  LEU F CG  1 
ATOM   10624 C  CD1 . LEU F 1 85  ? 79.887  75.891  24.190  1.00 43.74  ? 85  LEU F CD1 1 
ATOM   10625 C  CD2 . LEU F 1 85  ? 79.451  73.465  23.798  1.00 48.93  ? 85  LEU F CD2 1 
ATOM   10626 N  N   . LYS F 1 86  ? 83.474  73.983  20.242  1.00 59.58  ? 86  LYS F N   1 
ATOM   10627 C  CA  . LYS F 1 86  ? 83.876  74.139  18.850  1.00 61.91  ? 86  LYS F CA  1 
ATOM   10628 C  C   . LYS F 1 86  ? 83.938  72.792  18.139  1.00 62.51  ? 86  LYS F C   1 
ATOM   10629 O  O   . LYS F 1 86  ? 83.689  72.721  16.934  1.00 65.56  ? 86  LYS F O   1 
ATOM   10630 C  CB  . LYS F 1 86  ? 85.228  74.846  18.766  1.00 61.88  ? 86  LYS F CB  1 
ATOM   10631 C  CG  . LYS F 1 86  ? 85.192  76.232  18.144  1.00 62.59  ? 86  LYS F CG  1 
ATOM   10632 C  CD  . LYS F 1 86  ? 86.392  77.044  18.622  1.00 60.57  ? 86  LYS F CD  1 
ATOM   10633 C  CE  . LYS F 1 86  ? 86.362  78.475  18.121  1.00 61.62  ? 86  LYS F CE  1 
ATOM   10634 N  NZ  . LYS F 1 86  ? 87.552  79.238  18.605  1.00 59.17  ? 86  LYS F NZ  1 
ATOM   10635 N  N   . ALA F 1 87  ? 84.130  71.705  18.879  1.00 61.10  ? 87  ALA F N   1 
ATOM   10636 C  CA  . ALA F 1 87  ? 84.123  70.365  18.255  1.00 60.63  ? 87  ALA F CA  1 
ATOM   10637 C  C   . ALA F 1 87  ? 82.708  69.779  18.220  1.00 63.06  ? 87  ALA F C   1 
ATOM   10638 O  O   . ALA F 1 87  ? 82.512  68.791  17.506  1.00 70.40  ? 87  ALA F O   1 
ATOM   10639 C  CB  . ALA F 1 87  ? 85.054  69.451  18.994  1.00 54.75  ? 87  ALA F CB  1 
ATOM   10640 N  N   . PHE F 1 88  ? 81.752  70.387  18.918  1.00 59.60  ? 88  PHE F N   1 
ATOM   10641 C  CA  . PHE F 1 88  ? 80.380  69.816  18.999  1.00 64.49  ? 88  PHE F CA  1 
ATOM   10642 C  C   . PHE F 1 88  ? 79.522  70.327  17.842  1.00 62.56  ? 88  PHE F C   1 
ATOM   10643 O  O   . PHE F 1 88  ? 78.843  69.521  17.201  1.00 67.88  ? 88  PHE F O   1 
ATOM   10644 C  CB  . PHE F 1 88  ? 79.728  70.158  20.341  1.00 61.86  ? 88  PHE F CB  1 
ATOM   10645 C  CG  . PHE F 1 88  ? 78.233  69.990  20.372  1.00 59.97  ? 88  PHE F CG  1 
ATOM   10646 C  CD1 . PHE F 1 88  ? 77.667  68.731  20.462  1.00 54.85  ? 88  PHE F CD1 1 
ATOM   10647 C  CD2 . PHE F 1 88  ? 77.396  71.089  20.300  1.00 58.67  ? 88  PHE F CD2 1 
ATOM   10648 C  CE1 . PHE F 1 88  ? 76.292  68.577  20.481  1.00 59.01  ? 88  PHE F CE1 1 
ATOM   10649 C  CE2 . PHE F 1 88  ? 76.021  70.933  20.320  1.00 56.06  ? 88  PHE F CE2 1 
ATOM   10650 C  CZ  . PHE F 1 88  ? 75.473  69.678  20.411  1.00 57.89  ? 88  PHE F CZ  1 
ATOM   10651 N  N   . GLY F 1 89  ? 79.543  71.632  17.608  1.00 64.47  ? 89  GLY F N   1 
ATOM   10652 C  CA  . GLY F 1 89  ? 78.765  72.243  16.521  1.00 70.43  ? 89  GLY F CA  1 
ATOM   10653 C  C   . GLY F 1 89  ? 78.560  73.721  16.786  1.00 78.57  ? 89  GLY F C   1 
ATOM   10654 O  O   . GLY F 1 89  ? 77.899  74.374  15.960  1.00 86.07  ? 89  GLY F O   1 
ATOM   10655 N  N   . ILE F 1 90  ? 79.139  74.256  17.866  1.00 82.15  ? 90  ILE F N   1 
ATOM   10656 C  CA  . ILE F 1 90  ? 78.797  75.668  18.221  1.00 92.86  ? 90  ILE F CA  1 
ATOM   10657 C  C   . ILE F 1 90  ? 80.030  76.556  18.439  1.00 76.50  ? 90  ILE F C   1 
ATOM   10658 O  O   . ILE F 1 90  ? 80.937  76.164  19.185  1.00 64.03  ? 90  ILE F O   1 
ATOM   10659 C  CB  . ILE F 1 90  ? 77.800  75.685  19.402  1.00 104.27 ? 90  ILE F CB  1 
ATOM   10660 C  CG1 . ILE F 1 90  ? 77.569  77.099  19.934  1.00 105.40 ? 90  ILE F CG1 1 
ATOM   10661 C  CG2 . ILE F 1 90  ? 78.235  74.730  20.500  1.00 97.57  ? 90  ILE F CG2 1 
ATOM   10662 C  CD1 . ILE F 1 90  ? 78.367  77.394  21.163  1.00 100.14 ? 90  ILE F CD1 1 
ATOM   10663 N  N   . GLU F 1 91  ? 80.021  77.734  17.815  1.00 74.69  ? 91  GLU F N   1 
ATOM   10664 C  CA  . GLU F 1 91  ? 81.131  78.706  17.933  1.00 68.02  ? 91  GLU F CA  1 
ATOM   10665 C  C   . GLU F 1 91  ? 80.868  79.644  19.111  1.00 63.66  ? 91  GLU F C   1 
ATOM   10666 O  O   . GLU F 1 91  ? 79.697  79.895  19.424  1.00 62.06  ? 91  GLU F O   1 
ATOM   10667 C  CB  . GLU F 1 91  ? 81.154  79.519  16.643  1.00 71.33  ? 91  GLU F CB  1 
ATOM   10668 C  CG  . GLU F 1 91  ? 82.538  79.898  16.156  1.00 76.14  ? 91  GLU F CG  1 
ATOM   10669 C  CD  . GLU F 1 91  ? 83.367  78.755  15.601  1.00 74.61  ? 91  GLU F CD  1 
ATOM   10670 O  OE1 . GLU F 1 91  ? 84.582  78.947  15.439  1.00 67.62  ? 91  GLU F OE1 1 
ATOM   10671 O  OE2 . GLU F 1 91  ? 82.796  77.686  15.328  1.00 75.07  ? 91  GLU F OE2 1 
ATOM   10672 N  N   . PRO F 1 92  ? 81.912  80.199  19.751  1.00 60.02  ? 92  PRO F N   1 
ATOM   10673 C  CA  . PRO F 1 92  ? 81.731  81.113  20.873  1.00 57.97  ? 92  PRO F CA  1 
ATOM   10674 C  C   . PRO F 1 92  ? 80.607  82.157  20.769  1.00 53.29  ? 92  PRO F C   1 
ATOM   10675 O  O   . PRO F 1 92  ? 80.058  82.485  21.789  1.00 53.96  ? 92  PRO F O   1 
ATOM   10676 C  CB  . PRO F 1 92  ? 83.079  81.841  20.871  1.00 52.26  ? 92  PRO F CB  1 
ATOM   10677 C  CG  . PRO F 1 92  ? 84.065  80.784  20.472  1.00 59.05  ? 92  PRO F CG  1 
ATOM   10678 C  CD  . PRO F 1 92  ? 83.321  79.927  19.474  1.00 59.77  ? 92  PRO F CD  1 
ATOM   10679 N  N   . ALA F 1 93  ? 80.289  82.656  19.577  1.00 49.37  ? 93  ALA F N   1 
ATOM   10680 C  CA  . ALA F 1 93  ? 79.315  83.735  19.492  1.00 45.98  ? 93  ALA F CA  1 
ATOM   10681 C  C   . ALA F 1 93  ? 77.880  83.240  19.563  1.00 47.05  ? 93  ALA F C   1 
ATOM   10682 O  O   . ALA F 1 93  ? 76.972  84.049  19.779  1.00 46.95  ? 93  ALA F O   1 
ATOM   10683 C  CB  . ALA F 1 93  ? 79.514  84.534  18.206  1.00 48.84  ? 93  ALA F CB  1 
ATOM   10684 N  N   . ASP F 1 94  ? 77.652  81.937  19.404  1.00 47.15  ? 94  ASP F N   1 
ATOM   10685 C  CA  . ASP F 1 94  ? 76.309  81.373  19.400  1.00 48.87  ? 94  ASP F CA  1 
ATOM   10686 C  C   . ASP F 1 94  ? 75.897  80.840  20.766  1.00 46.41  ? 94  ASP F C   1 
ATOM   10687 O  O   . ASP F 1 94  ? 75.135  79.871  20.847  1.00 46.59  ? 94  ASP F O   1 
ATOM   10688 C  CB  . ASP F 1 94  ? 76.201  80.275  18.345  1.00 52.07  ? 94  ASP F CB  1 
ATOM   10689 C  CG  . ASP F 1 94  ? 76.711  80.728  17.003  1.00 58.37  ? 94  ASP F CG  1 
ATOM   10690 O  OD1 . ASP F 1 94  ? 76.291  81.823  16.560  1.00 50.14  ? 94  ASP F OD1 1 
ATOM   10691 O  OD2 . ASP F 1 94  ? 77.538  80.001  16.403  1.00 66.19  ? 94  ASP F OD2 1 
ATOM   10692 N  N   . VAL F 1 95  ? 76.392  81.447  21.842  1.00 45.95  ? 95  VAL F N   1 
ATOM   10693 C  CA  . VAL F 1 95  ? 75.926  81.170  23.198  1.00 40.03  ? 95  VAL F CA  1 
ATOM   10694 C  C   . VAL F 1 95  ? 75.241  82.428  23.710  1.00 41.09  ? 95  VAL F C   1 
ATOM   10695 O  O   . VAL F 1 95  ? 75.842  83.511  23.731  1.00 43.12  ? 95  VAL F O   1 
ATOM   10696 C  CB  . VAL F 1 95  ? 77.071  80.739  24.125  1.00 41.59  ? 95  VAL F CB  1 
ATOM   10697 C  CG1 . VAL F 1 95  ? 76.532  80.429  25.525  1.00 39.04  ? 95  VAL F CG1 1 
ATOM   10698 C  CG2 . VAL F 1 95  ? 77.784  79.532  23.548  1.00 38.09  ? 95  VAL F CG2 1 
ATOM   10699 N  N   . ARG F 1 96  ? 73.977  82.294  24.098  1.00 38.62  ? 96  ARG F N   1 
ATOM   10700 C  CA  . ARG F 1 96  ? 73.186  83.445  24.507  1.00 36.73  ? 96  ARG F CA  1 
ATOM   10701 C  C   . ARG F 1 96  ? 73.308  83.733  26.000  1.00 36.25  ? 96  ARG F C   1 
ATOM   10702 O  O   . ARG F 1 96  ? 73.302  84.898  26.411  1.00 39.36  ? 96  ARG F O   1 
ATOM   10703 C  CB  . ARG F 1 96  ? 71.723  83.215  24.142  1.00 35.47  ? 96  ARG F CB  1 
ATOM   10704 C  CG  . ARG F 1 96  ? 70.852  84.403  24.401  1.00 33.52  ? 96  ARG F CG  1 
ATOM   10705 C  CD  . ARG F 1 96  ? 69.489  84.189  23.806  1.00 34.43  ? 96  ARG F CD  1 
ATOM   10706 N  NE  . ARG F 1 96  ? 68.522  85.127  24.356  1.00 34.69  ? 96  ARG F NE  1 
ATOM   10707 C  CZ  . ARG F 1 96  ? 67.241  85.142  24.026  1.00 37.01  ? 96  ARG F CZ  1 
ATOM   10708 N  NH1 . ARG F 1 96  ? 66.735  84.251  23.190  1.00 39.59  ? 96  ARG F NH1 1 
ATOM   10709 N  NH2 . ARG F 1 96  ? 66.451  86.078  24.540  1.00 33.43  ? 96  ARG F NH2 1 
ATOM   10710 N  N   . TYR F 1 97  ? 73.419  82.691  26.820  1.00 35.98  ? 97  TYR F N   1 
ATOM   10711 C  CA  . TYR F 1 97  ? 73.459  82.828  28.268  1.00 35.23  ? 97  TYR F CA  1 
ATOM   10712 C  C   . TYR F 1 97  ? 74.570  81.972  28.842  1.00 33.09  ? 97  TYR F C   1 
ATOM   10713 O  O   . TYR F 1 97  ? 74.721  80.805  28.473  1.00 34.51  ? 97  TYR F O   1 
ATOM   10714 C  CB  . TYR F 1 97  ? 72.134  82.416  28.906  1.00 31.40  ? 97  TYR F CB  1 
ATOM   10715 C  CG  . TYR F 1 97  ? 70.978  83.296  28.529  1.00 30.61  ? 97  TYR F CG  1 
ATOM   10716 C  CD1 . TYR F 1 97  ? 70.983  84.644  28.831  1.00 32.55  ? 97  TYR F CD1 1 
ATOM   10717 C  CD2 . TYR F 1 97  ? 69.874  82.773  27.875  1.00 32.07  ? 97  TYR F CD2 1 
ATOM   10718 C  CE1 . TYR F 1 97  ? 69.918  85.446  28.499  1.00 34.64  ? 97  TYR F CE1 1 
ATOM   10719 C  CE2 . TYR F 1 97  ? 68.800  83.568  27.525  1.00 29.27  ? 97  TYR F CE2 1 
ATOM   10720 C  CZ  . TYR F 1 97  ? 68.825  84.895  27.835  1.00 32.90  ? 97  TYR F CZ  1 
ATOM   10721 O  OH  . TYR F 1 97  ? 67.751  85.691  27.501  1.00 35.95  ? 97  TYR F OH  1 
ATOM   10722 N  N   . VAL F 1 98  ? 75.337  82.553  29.754  1.00 33.39  ? 98  VAL F N   1 
ATOM   10723 C  CA  . VAL F 1 98  ? 76.207  81.792  30.644  1.00 32.41  ? 98  VAL F CA  1 
ATOM   10724 C  C   . VAL F 1 98  ? 75.585  81.857  32.028  1.00 30.22  ? 98  VAL F C   1 
ATOM   10725 O  O   . VAL F 1 98  ? 75.382  82.947  32.574  1.00 29.52  ? 98  VAL F O   1 
ATOM   10726 C  CB  . VAL F 1 98  ? 77.650  82.320  30.638  1.00 31.19  ? 98  VAL F CB  1 
ATOM   10727 C  CG1 . VAL F 1 98  ? 78.489  81.585  31.667  1.00 26.73  ? 98  VAL F CG1 1 
ATOM   10728 C  CG2 . VAL F 1 98  ? 78.263  82.104  29.262  1.00 34.77  ? 98  VAL F CG2 1 
ATOM   10729 N  N   . LEU F 1 99  ? 75.232  80.702  32.572  1.00 30.86  ? 99  LEU F N   1 
ATOM   10730 C  CA  . LEU F 1 99  ? 74.705  80.616  33.923  1.00 27.34  ? 99  LEU F CA  1 
ATOM   10731 C  C   . LEU F 1 99  ? 75.817  80.189  34.869  1.00 29.75  ? 99  LEU F C   1 
ATOM   10732 O  O   . LEU F 1 99  ? 76.659  79.359  34.515  1.00 27.58  ? 99  LEU F O   1 
ATOM   10733 C  CB  . LEU F 1 99  ? 73.543  79.626  34.001  1.00 29.61  ? 99  LEU F CB  1 
ATOM   10734 C  CG  . LEU F 1 99  ? 72.487  79.647  32.888  1.00 27.34  ? 99  LEU F CG  1 
ATOM   10735 C  CD1 . LEU F 1 99  ? 71.359  78.669  33.221  1.00 26.50  ? 99  LEU F CD1 1 
ATOM   10736 C  CD2 . LEU F 1 99  ? 71.938  81.040  32.644  1.00 24.30  ? 99  LEU F CD2 1 
ATOM   10737 N  N   . HIS F 1 100 ? 75.830  80.754  36.074  1.00 25.08  ? 100 HIS F N   1 
ATOM   10738 C  CA  . HIS F 1 100 ? 76.821  80.359  37.066  1.00 29.48  ? 100 HIS F CA  1 
ATOM   10739 C  C   . HIS F 1 100 ? 76.152  79.835  38.328  1.00 27.08  ? 100 HIS F C   1 
ATOM   10740 O  O   . HIS F 1 100 ? 75.373  80.546  38.968  1.00 25.05  ? 100 HIS F O   1 
ATOM   10741 C  CB  . HIS F 1 100 ? 77.759  81.515  37.381  1.00 27.41  ? 100 HIS F CB  1 
ATOM   10742 C  CG  . HIS F 1 100 ? 78.865  81.652  36.395  1.00 29.16  ? 100 HIS F CG  1 
ATOM   10743 N  ND1 . HIS F 1 100 ? 79.857  80.702  36.265  1.00 30.90  ? 100 HIS F ND1 1 
ATOM   10744 C  CD2 . HIS F 1 100 ? 79.141  82.616  35.486  1.00 30.05  ? 100 HIS F CD2 1 
ATOM   10745 C  CE1 . HIS F 1 100 ? 80.699  81.079  35.320  1.00 32.20  ? 100 HIS F CE1 1 
ATOM   10746 N  NE2 . HIS F 1 100 ? 80.291  82.239  34.836  1.00 32.02  ? 100 HIS F NE2 1 
ATOM   10747 N  N   . SER F 1 101 ? 76.450  78.581  38.672  1.00 28.29  ? 101 SER F N   1 
ATOM   10748 C  CA  . SER F 1 101 ? 76.039  78.052  39.967  1.00 29.10  ? 101 SER F CA  1 
ATOM   10749 C  C   . SER F 1 101 ? 76.710  78.829  41.093  1.00 28.58  ? 101 SER F C   1 
ATOM   10750 O  O   . SER F 1 101 ? 76.063  79.200  42.077  1.00 24.84  ? 101 SER F O   1 
ATOM   10751 C  CB  . SER F 1 101 ? 76.392  76.572  40.059  1.00 28.41  ? 101 SER F CB  1 
ATOM   10752 O  OG  . SER F 1 101 ? 77.809  76.417  40.022  1.00 33.93  ? 101 SER F OG  1 
ATOM   10753 N  N   . HIS F 1 102 ? 78.017  79.060  40.963  1.00 27.12  ? 102 HIS F N   1 
ATOM   10754 C  CA  . HIS F 1 102 ? 78.801  79.956  41.808  1.00 23.78  ? 102 HIS F CA  1 
ATOM   10755 C  C   . HIS F 1 102 ? 80.074  80.295  41.044  1.00 29.29  ? 102 HIS F C   1 
ATOM   10756 O  O   . HIS F 1 102 ? 80.240  79.910  39.880  1.00 26.25  ? 102 HIS F O   1 
ATOM   10757 C  CB  . HIS F 1 102 ? 79.099  79.358  43.192  1.00 25.05  ? 102 HIS F CB  1 
ATOM   10758 C  CG  . HIS F 1 102 ? 79.745  78.006  43.162  1.00 29.71  ? 102 HIS F CG  1 
ATOM   10759 N  ND1 . HIS F 1 102 ? 79.333  76.992  42.322  1.00 32.40  ? 102 HIS F ND1 1 
ATOM   10760 C  CD2 . HIS F 1 102 ? 80.765  77.493  43.895  1.00 28.37  ? 102 HIS F CD2 1 
ATOM   10761 C  CE1 . HIS F 1 102 ? 80.076  75.917  42.530  1.00 32.72  ? 102 HIS F CE1 1 
ATOM   10762 N  NE2 . HIS F 1 102 ? 80.949  76.193  43.483  1.00 29.93  ? 102 HIS F NE2 1 
ATOM   10763 N  N   . LEU F 1 103 ? 80.981  81.022  41.696  1.00 23.19  ? 103 LEU F N   1 
ATOM   10764 C  CA  . LEU F 1 103 ? 82.150  81.540  41.007  1.00 22.97  ? 103 LEU F CA  1 
ATOM   10765 C  C   . LEU F 1 103 ? 83.464  80.920  41.492  1.00 26.46  ? 103 LEU F C   1 
ATOM   10766 O  O   . LEU F 1 103 ? 84.528  81.508  41.305  1.00 32.41  ? 103 LEU F O   1 
ATOM   10767 C  CB  . LEU F 1 103 ? 82.166  83.057  41.122  1.00 23.51  ? 103 LEU F CB  1 
ATOM   10768 C  CG  . LEU F 1 103 ? 80.963  83.660  40.370  1.00 29.04  ? 103 LEU F CG  1 
ATOM   10769 C  CD1 . LEU F 1 103 ? 80.866  85.150  40.587  1.00 24.89  ? 103 LEU F CD1 1 
ATOM   10770 C  CD2 . LEU F 1 103 ? 81.033  83.354  38.868  1.00 26.33  ? 103 LEU F CD2 1 
ATOM   10771 N  N   . HIS F 1 104 ? 83.415  79.686  41.965  1.00 27.20  ? 104 HIS F N   1 
ATOM   10772 C  CA  . HIS F 1 104 ? 84.659  78.959  42.325  1.00 28.76  ? 104 HIS F CA  1 
ATOM   10773 C  C   . HIS F 1 104 ? 85.468  78.595  41.070  1.00 33.53  ? 104 HIS F C   1 
ATOM   10774 O  O   . HIS F 1 104 ? 84.898  78.502  39.971  1.00 26.83  ? 104 HIS F O   1 
ATOM   10775 C  CB  . HIS F 1 104 ? 84.341  77.732  43.179  1.00 30.27  ? 104 HIS F CB  1 
ATOM   10776 C  CG  . HIS F 1 104 ? 83.942  78.036  44.579  1.00 30.22  ? 104 HIS F CG  1 
ATOM   10777 N  ND1 . HIS F 1 104 ? 83.556  77.051  45.459  1.00 27.68  ? 104 HIS F ND1 1 
ATOM   10778 C  CD2 . HIS F 1 104 ? 83.851  79.186  45.248  1.00 29.03  ? 104 HIS F CD2 1 
ATOM   10779 C  CE1 . HIS F 1 104 ? 83.249  77.602  46.619  1.00 31.07  ? 104 HIS F CE1 1 
ATOM   10780 N  NE2 . HIS F 1 104 ? 83.424  78.896  46.513  1.00 28.28  ? 104 HIS F NE2 1 
ATOM   10781 N  N   . LEU F 1 105 ? 86.770  78.362  41.250  1.00 35.12  ? 105 LEU F N   1 
ATOM   10782 C  CA  . LEU F 1 105 ? 87.708  78.097  40.123  1.00 35.06  ? 105 LEU F CA  1 
ATOM   10783 C  C   . LEU F 1 105 ? 87.210  77.013  39.156  1.00 37.64  ? 105 LEU F C   1 
ATOM   10784 O  O   . LEU F 1 105 ? 87.479  77.155  37.969  1.00 36.15  ? 105 LEU F O   1 
ATOM   10785 C  CB  . LEU F 1 105 ? 89.076  77.726  40.706  1.00 33.36  ? 105 LEU F CB  1 
ATOM   10786 C  CG  . LEU F 1 105 ? 89.101  77.062  42.079  1.00 36.00  ? 105 LEU F CG  1 
ATOM   10787 C  CD1 . LEU F 1 105 ? 88.814  75.577  41.975  1.00 39.36  ? 105 LEU F CD1 1 
ATOM   10788 C  CD2 . LEU F 1 105 ? 90.457  77.274  42.721  1.00 39.14  ? 105 LEU F CD2 1 
ATOM   10789 N  N   . ASP F 1 106 ? 86.546  75.967  39.645  1.00 35.29  ? 106 ASP F N   1 
ATOM   10790 C  CA  . ASP F 1 106 ? 86.151  74.909  38.723  1.00 39.94  ? 106 ASP F CA  1 
ATOM   10791 C  C   . ASP F 1 106 ? 84.781  75.165  38.112  1.00 37.42  ? 106 ASP F C   1 
ATOM   10792 O  O   . ASP F 1 106 ? 84.158  74.239  37.578  1.00 36.14  ? 106 ASP F O   1 
ATOM   10793 C  CB  . ASP F 1 106 ? 86.185  73.546  39.420  1.00 37.38  ? 106 ASP F CB  1 
ATOM   10794 C  CG  . ASP F 1 106 ? 85.553  73.573  40.793  1.00 39.50  ? 106 ASP F CG  1 
ATOM   10795 O  OD1 . ASP F 1 106 ? 85.663  74.607  41.492  1.00 43.40  ? 106 ASP F OD1 1 
ATOM   10796 O  OD2 . ASP F 1 106 ? 84.967  72.552  41.190  1.00 42.51  ? 106 ASP F OD2 1 
ATOM   10797 N  N   . HIS F 1 107 ? 84.292  76.405  38.193  1.00 37.01  ? 107 HIS F N   1 
ATOM   10798 C  CA  . HIS F 1 107 ? 82.995  76.744  37.622  1.00 33.23  ? 107 HIS F CA  1 
ATOM   10799 C  C   . HIS F 1 107 ? 83.038  78.084  36.908  1.00 36.64  ? 107 HIS F C   1 
ATOM   10800 O  O   . HIS F 1 107 ? 81.978  78.632  36.583  1.00 36.69  ? 107 HIS F O   1 
ATOM   10801 C  CB  . HIS F 1 107 ? 81.897  76.754  38.693  1.00 30.31  ? 107 HIS F CB  1 
ATOM   10802 C  CG  . HIS F 1 107 ? 81.735  75.444  39.403  1.00 32.45  ? 107 HIS F CG  1 
ATOM   10803 N  ND1 . HIS F 1 107 ? 80.820  74.486  39.007  1.00 29.02  ? 107 HIS F ND1 1 
ATOM   10804 C  CD2 . HIS F 1 107 ? 82.371  74.931  40.485  1.00 32.99  ? 107 HIS F CD2 1 
ATOM   10805 C  CE1 . HIS F 1 107 ? 80.899  73.441  39.814  1.00 25.99  ? 107 HIS F CE1 1 
ATOM   10806 N  NE2 . HIS F 1 107 ? 81.829  73.686  40.720  1.00 31.26  ? 107 HIS F NE2 1 
ATOM   10807 N  N   . THR F 1 108 ? 84.227  78.618  36.626  1.00 34.95  ? 108 THR F N   1 
ATOM   10808 C  CA  . THR F 1 108 ? 84.350  79.905  35.954  1.00 35.72  ? 108 THR F CA  1 
ATOM   10809 C  C   . THR F 1 108 ? 85.099  79.789  34.629  1.00 36.92  ? 108 THR F C   1 
ATOM   10810 O  O   . THR F 1 108 ? 85.563  80.799  34.089  1.00 36.55  ? 108 THR F O   1 
ATOM   10811 C  CB  . THR F 1 108 ? 85.032  80.915  36.882  1.00 35.43  ? 108 THR F CB  1 
ATOM   10812 O  OG1 . THR F 1 108 ? 86.220  80.336  37.430  1.00 35.78  ? 108 THR F OG1 1 
ATOM   10813 C  CG2 . THR F 1 108 ? 84.095  81.283  38.034  1.00 31.04  ? 108 THR F CG2 1 
ATOM   10814 N  N   . GLY F 1 109 ? 85.208  78.576  34.082  1.00 39.98  ? 109 GLY F N   1 
ATOM   10815 C  CA  . GLY F 1 109 ? 85.878  78.414  32.801  1.00 41.61  ? 109 GLY F CA  1 
ATOM   10816 C  C   . GLY F 1 109 ? 85.195  79.146  31.662  1.00 42.77  ? 109 GLY F C   1 
ATOM   10817 O  O   . GLY F 1 109 ? 85.856  79.586  30.718  1.00 42.18  ? 109 GLY F O   1 
ATOM   10818 N  N   . ALA F 1 110 ? 83.871  79.307  31.734  1.00 41.44  ? 110 ALA F N   1 
ATOM   10819 C  CA  . ALA F 1 110 ? 83.161  79.935  30.627  1.00 40.14  ? 110 ALA F CA  1 
ATOM   10820 C  C   . ALA F 1 110 ? 83.174  81.458  30.689  1.00 39.14  ? 110 ALA F C   1 
ATOM   10821 O  O   . ALA F 1 110 ? 82.908  82.100  29.670  1.00 40.70  ? 110 ALA F O   1 
ATOM   10822 C  CB  . ALA F 1 110 ? 81.712  79.437  30.575  1.00 34.95  ? 110 ALA F CB  1 
ATOM   10823 N  N   . THR F 1 111 ? 83.511  82.044  31.836  1.00 37.05  ? 111 THR F N   1 
ATOM   10824 C  CA  . THR F 1 111 ? 83.220  83.454  32.086  1.00 35.62  ? 111 THR F CA  1 
ATOM   10825 C  C   . THR F 1 111 ? 83.953  84.366  31.116  1.00 35.38  ? 111 THR F C   1 
ATOM   10826 O  O   . THR F 1 111 ? 85.184  84.380  31.067  1.00 44.05  ? 111 THR F O   1 
ATOM   10827 C  CB  . THR F 1 111 ? 83.592  83.835  33.524  1.00 36.11  ? 111 THR F CB  1 
ATOM   10828 O  OG1 . THR F 1 111 ? 82.925  82.973  34.458  1.00 36.98  ? 111 THR F OG1 1 
ATOM   10829 C  CG2 . THR F 1 111 ? 83.208  85.261  33.788  1.00 31.13  ? 111 THR F CG2 1 
ATOM   10830 N  N   . GLY F 1 112 ? 83.199  85.173  30.384  1.00 33.86  ? 112 GLY F N   1 
ATOM   10831 C  CA  . GLY F 1 112 ? 83.794  86.070  29.423  1.00 44.37  ? 112 GLY F CA  1 
ATOM   10832 C  C   . GLY F 1 112 ? 84.382  85.417  28.189  1.00 45.07  ? 112 GLY F C   1 
ATOM   10833 O  O   . GLY F 1 112 ? 84.950  86.128  27.353  1.00 44.00  ? 112 GLY F O   1 
ATOM   10834 N  N   . ARG F 1 113 ? 84.263  84.093  28.036  1.00 40.09  ? 113 ARG F N   1 
ATOM   10835 C  CA  . ARG F 1 113 ? 84.759  83.441  26.828  1.00 43.46  ? 113 ARG F CA  1 
ATOM   10836 C  C   . ARG F 1 113 ? 83.763  83.520  25.678  1.00 48.11  ? 113 ARG F C   1 
ATOM   10837 O  O   . ARG F 1 113 ? 84.143  83.266  24.529  1.00 49.67  ? 113 ARG F O   1 
ATOM   10838 C  CB  . ARG F 1 113 ? 85.090  81.964  27.065  1.00 42.19  ? 113 ARG F CB  1 
ATOM   10839 C  CG  . ARG F 1 113 ? 85.742  81.574  28.387  1.00 44.73  ? 113 ARG F CG  1 
ATOM   10840 C  CD  . ARG F 1 113 ? 86.829  82.514  28.857  1.00 43.02  ? 113 ARG F CD  1 
ATOM   10841 N  NE  . ARG F 1 113 ? 87.880  81.795  29.569  1.00 47.83  ? 113 ARG F NE  1 
ATOM   10842 C  CZ  . ARG F 1 113 ? 88.079  81.834  30.881  1.00 48.57  ? 113 ARG F CZ  1 
ATOM   10843 N  NH1 . ARG F 1 113 ? 87.249  82.480  31.693  1.00 43.39  ? 113 ARG F NH1 1 
ATOM   10844 N  NH2 . ARG F 1 113 ? 89.140  81.213  31.390  1.00 44.65  ? 113 ARG F NH2 1 
ATOM   10845 N  N   . PHE F 1 114 ? 82.507  83.858  25.957  1.00 46.79  ? 114 PHE F N   1 
ATOM   10846 C  CA  . PHE F 1 114 ? 81.459  83.899  24.939  1.00 43.25  ? 114 PHE F CA  1 
ATOM   10847 C  C   . PHE F 1 114 ? 80.985  85.334  24.800  1.00 47.46  ? 114 PHE F C   1 
ATOM   10848 O  O   . PHE F 1 114 ? 80.245  85.835  25.665  1.00 52.22  ? 114 PHE F O   1 
ATOM   10849 C  CB  . PHE F 1 114 ? 80.319  82.952  25.304  1.00 44.49  ? 114 PHE F CB  1 
ATOM   10850 C  CG  . PHE F 1 114 ? 80.787  81.549  25.556  1.00 44.05  ? 114 PHE F CG  1 
ATOM   10851 C  CD1 . PHE F 1 114 ? 81.177  81.150  26.825  1.00 41.10  ? 114 PHE F CD1 1 
ATOM   10852 C  CD2 . PHE F 1 114 ? 80.920  80.654  24.509  1.00 45.45  ? 114 PHE F CD2 1 
ATOM   10853 C  CE1 . PHE F 1 114 ? 81.633  79.870  27.052  1.00 41.61  ? 114 PHE F CE1 1 
ATOM   10854 C  CE2 . PHE F 1 114 ? 81.389  79.367  24.726  1.00 43.13  ? 114 PHE F CE2 1 
ATOM   10855 C  CZ  . PHE F 1 114 ? 81.743  78.976  25.997  1.00 46.02  ? 114 PHE F CZ  1 
ATOM   10856 N  N   . PRO F 1 115 ? 81.372  86.028  23.723  1.00 51.83  ? 115 PRO F N   1 
ATOM   10857 C  CA  . PRO F 1 115 ? 81.334  87.502  23.732  1.00 47.62  ? 115 PRO F CA  1 
ATOM   10858 C  C   . PRO F 1 115 ? 79.944  88.096  23.819  1.00 48.15  ? 115 PRO F C   1 
ATOM   10859 O  O   . PRO F 1 115 ? 79.820  89.265  24.210  1.00 53.79  ? 115 PRO F O   1 
ATOM   10860 C  CB  . PRO F 1 115 ? 82.005  87.881  22.402  1.00 50.67  ? 115 PRO F CB  1 
ATOM   10861 C  CG  . PRO F 1 115 ? 82.712  86.618  21.926  1.00 51.83  ? 115 PRO F CG  1 
ATOM   10862 C  CD  . PRO F 1 115 ? 81.883  85.488  22.451  1.00 49.12  ? 115 PRO F CD  1 
ATOM   10863 N  N   . ASN F 1 116 ? 78.901  87.355  23.455  1.00 44.10  ? 116 ASN F N   1 
ATOM   10864 C  CA  . ASN F 1 116 ? 77.545  87.882  23.464  1.00 42.85  ? 116 ASN F CA  1 
ATOM   10865 C  C   . ASN F 1 116 ? 76.706  87.317  24.600  1.00 44.18  ? 116 ASN F C   1 
ATOM   10866 O  O   . ASN F 1 116 ? 75.508  87.609  24.682  1.00 41.54  ? 116 ASN F O   1 
ATOM   10867 C  CB  . ASN F 1 116 ? 76.851  87.590  22.122  1.00 43.66  ? 116 ASN F CB  1 
ATOM   10868 C  CG  . ASN F 1 116 ? 77.730  87.928  20.911  1.00 49.68  ? 116 ASN F CG  1 
ATOM   10869 O  OD1 . ASN F 1 116 ? 78.470  87.081  20.413  1.00 50.54  ? 116 ASN F OD1 1 
ATOM   10870 N  ND2 . ASN F 1 116 ? 77.646  89.163  20.440  1.00 42.57  ? 116 ASN F ND2 1 
ATOM   10871 N  N   . ALA F 1 117 ? 77.288  86.495  25.461  1.00 41.04  ? 117 ALA F N   1 
ATOM   10872 C  CA  . ALA F 1 117 ? 76.495  85.764  26.433  1.00 43.33  ? 117 ALA F CA  1 
ATOM   10873 C  C   . ALA F 1 117 ? 76.214  86.643  27.647  1.00 40.35  ? 117 ALA F C   1 
ATOM   10874 O  O   . ALA F 1 117 ? 77.134  87.234  28.221  1.00 42.08  ? 117 ALA F O   1 
ATOM   10875 C  CB  . ALA F 1 117 ? 77.223  84.486  26.843  1.00 38.18  ? 117 ALA F CB  1 
ATOM   10876 N  N   . ILE F 1 118 ? 74.942  86.741  28.024  1.00 40.40  ? 118 ILE F N   1 
ATOM   10877 C  CA  . ILE F 1 118 ? 74.570  87.369  29.290  1.00 39.14  ? 118 ILE F CA  1 
ATOM   10878 C  C   . ILE F 1 118 ? 74.902  86.394  30.416  1.00 34.32  ? 118 ILE F C   1 
ATOM   10879 O  O   . ILE F 1 118 ? 74.440  85.248  30.410  1.00 34.33  ? 118 ILE F O   1 
ATOM   10880 C  CB  . ILE F 1 118 ? 73.081  87.740  29.308  1.00 36.22  ? 118 ILE F CB  1 
ATOM   10881 C  CG1 . ILE F 1 118 ? 72.835  89.072  28.618  1.00 39.32  ? 118 ILE F CG1 1 
ATOM   10882 C  CG2 . ILE F 1 118 ? 72.584  87.865  30.725  1.00 35.32  ? 118 ILE F CG2 1 
ATOM   10883 C  CD1 . ILE F 1 118 ? 71.410  89.224  28.139  1.00 36.32  ? 118 ILE F CD1 1 
ATOM   10884 N  N   . HIS F 1 119 ? 75.706  86.840  31.380  1.00 30.92  ? 119 HIS F N   1 
ATOM   10885 C  CA  . HIS F 1 119 ? 76.114  85.998  32.500  1.00 31.54  ? 119 HIS F CA  1 
ATOM   10886 C  C   . HIS F 1 119 ? 75.151  86.203  33.672  1.00 31.26  ? 119 HIS F C   1 
ATOM   10887 O  O   . HIS F 1 119 ? 75.039  87.315  34.203  1.00 29.85  ? 119 HIS F O   1 
ATOM   10888 C  CB  . HIS F 1 119 ? 77.546  86.312  32.925  1.00 31.00  ? 119 HIS F CB  1 
ATOM   10889 C  CG  . HIS F 1 119 ? 78.586  85.938  31.913  1.00 37.89  ? 119 HIS F CG  1 
ATOM   10890 N  ND1 . HIS F 1 119 ? 78.636  86.493  30.650  1.00 39.19  ? 119 HIS F ND1 1 
ATOM   10891 C  CD2 . HIS F 1 119 ? 79.644  85.094  31.993  1.00 38.74  ? 119 HIS F CD2 1 
ATOM   10892 C  CE1 . HIS F 1 119 ? 79.674  86.001  29.997  1.00 34.74  ? 119 HIS F CE1 1 
ATOM   10893 N  NE2 . HIS F 1 119 ? 80.302  85.151  30.787  1.00 33.08  ? 119 HIS F NE2 1 
ATOM   10894 N  N   . ILE F 1 120 ? 74.459  85.136  34.066  1.00 29.22  ? 120 ILE F N   1 
ATOM   10895 C  CA  . ILE F 1 120 ? 73.452  85.177  35.122  1.00 26.11  ? 120 ILE F CA  1 
ATOM   10896 C  C   . ILE F 1 120 ? 73.992  84.439  36.343  1.00 26.78  ? 120 ILE F C   1 
ATOM   10897 O  O   . ILE F 1 120 ? 74.308  83.242  36.267  1.00 29.16  ? 120 ILE F O   1 
ATOM   10898 C  CB  . ILE F 1 120 ? 72.124  84.563  34.662  1.00 26.36  ? 120 ILE F CB  1 
ATOM   10899 C  CG1 . ILE F 1 120 ? 71.670  85.182  33.338  1.00 30.82  ? 120 ILE F CG1 1 
ATOM   10900 C  CG2 . ILE F 1 120 ? 71.036  84.754  35.726  1.00 22.65  ? 120 ILE F CG2 1 
ATOM   10901 C  CD1 . ILE F 1 120 ? 70.435  84.488  32.789  1.00 26.53  ? 120 ILE F CD1 1 
ATOM   10902 N  N   . VAL F 1 121 ? 74.082  85.156  37.470  1.00 24.27  ? 121 VAL F N   1 
ATOM   10903 C  CA  . VAL F 1 121 ? 74.549  84.614  38.746  1.00 23.18  ? 121 VAL F CA  1 
ATOM   10904 C  C   . VAL F 1 121 ? 73.881  85.415  39.866  1.00 22.80  ? 121 VAL F C   1 
ATOM   10905 O  O   . VAL F 1 121 ? 73.399  86.525  39.655  1.00 24.47  ? 121 VAL F O   1 
ATOM   10906 C  CB  . VAL F 1 121 ? 76.095  84.704  38.861  1.00 24.26  ? 121 VAL F CB  1 
ATOM   10907 C  CG1 . VAL F 1 121 ? 76.509  86.156  39.032  1.00 24.86  ? 121 VAL F CG1 1 
ATOM   10908 C  CG2 . VAL F 1 121 ? 76.629  83.861  40.008  1.00 24.29  ? 121 VAL F CG2 1 
ATOM   10909 N  N   . ARG F 1 122 ? 73.853  84.848  41.063  1.00 22.67  ? 122 ARG F N   1 
ATOM   10910 C  CA  . ARG F 1 122 ? 73.323  85.579  42.212  1.00 27.95  ? 122 ARG F CA  1 
ATOM   10911 C  C   . ARG F 1 122 ? 74.215  86.772  42.527  1.00 27.53  ? 122 ARG F C   1 
ATOM   10912 O  O   . ARG F 1 122 ? 75.445  86.652  42.538  1.00 26.20  ? 122 ARG F O   1 
ATOM   10913 C  CB  . ARG F 1 122 ? 73.209  84.663  43.429  1.00 22.47  ? 122 ARG F CB  1 
ATOM   10914 C  CG  . ARG F 1 122 ? 71.991  83.768  43.372  1.00 24.76  ? 122 ARG F CG  1 
ATOM   10915 C  CD  . ARG F 1 122 ? 71.627  83.219  44.742  1.00 24.21  ? 122 ARG F CD  1 
ATOM   10916 N  NE  . ARG F 1 122 ? 71.180  84.294  45.618  1.00 28.83  ? 122 ARG F NE  1 
ATOM   10917 C  CZ  . ARG F 1 122 ? 70.714  84.123  46.849  1.00 28.65  ? 122 ARG F CZ  1 
ATOM   10918 N  NH1 . ARG F 1 122 ? 70.644  82.919  47.409  1.00 23.28  ? 122 ARG F NH1 1 
ATOM   10919 N  NH2 . ARG F 1 122 ? 70.330  85.186  47.545  1.00 26.91  ? 122 ARG F NH2 1 
ATOM   10920 N  N   . ARG F 1 123 ? 73.595  87.932  42.758  1.00 26.19  ? 123 ARG F N   1 
ATOM   10921 C  CA  . ARG F 1 123 ? 74.360  89.120  43.140  1.00 27.49  ? 123 ARG F CA  1 
ATOM   10922 C  C   . ARG F 1 123 ? 75.314  88.827  44.292  1.00 26.27  ? 123 ARG F C   1 
ATOM   10923 O  O   . ARG F 1 123 ? 76.497  89.202  44.251  1.00 27.12  ? 123 ARG F O   1 
ATOM   10924 C  CB  . ARG F 1 123 ? 73.426  90.268  43.527  1.00 25.90  ? 123 ARG F CB  1 
ATOM   10925 C  CG  . ARG F 1 123 ? 74.162  91.349  44.308  1.00 27.22  ? 123 ARG F CG  1 
ATOM   10926 C  CD  . ARG F 1 123 ? 73.339  92.599  44.463  1.00 24.48  ? 123 ARG F CD  1 
ATOM   10927 N  NE  . ARG F 1 123 ? 73.126  93.235  43.171  1.00 27.13  ? 123 ARG F NE  1 
ATOM   10928 C  CZ  . ARG F 1 123 ? 74.039  93.969  42.551  1.00 28.70  ? 123 ARG F CZ  1 
ATOM   10929 N  NH1 . ARG F 1 123 ? 75.234  94.185  43.082  1.00 29.72  ? 123 ARG F NH1 1 
ATOM   10930 N  NH2 . ARG F 1 123 ? 73.739  94.517  41.382  1.00 28.58  ? 123 ARG F NH2 1 
ATOM   10931 N  N   . CYS F 1 124 ? 74.827  88.138  45.327  1.00 20.15  ? 124 CYS F N   1 
ATOM   10932 C  CA  . CYS F 1 124 ? 75.692  87.957  46.484  1.00 26.72  ? 124 CYS F CA  1 
ATOM   10933 C  C   . CYS F 1 124 ? 76.873  87.040  46.182  1.00 26.42  ? 124 CYS F C   1 
ATOM   10934 O  O   . CYS F 1 124 ? 77.907  87.157  46.848  1.00 25.79  ? 124 CYS F O   1 
ATOM   10935 C  CB  . CYS F 1 124 ? 74.892  87.459  47.698  1.00 23.74  ? 124 CYS F CB  1 
ATOM   10936 S  SG  . CYS F 1 124 ? 74.208  85.824  47.614  1.00 32.21  ? 124 CYS F SG  1 
ATOM   10937 N  N   . GLU F 1 125 ? 76.766  86.165  45.175  1.00 25.51  ? 125 GLU F N   1 
ATOM   10938 C  CA  . GLU F 1 125 ? 77.942  85.404  44.760  1.00 26.18  ? 125 GLU F CA  1 
ATOM   10939 C  C   . GLU F 1 125 ? 78.968  86.315  44.092  1.00 24.38  ? 125 GLU F C   1 
ATOM   10940 O  O   . GLU F 1 125 ? 80.152  86.299  44.448  1.00 23.39  ? 125 GLU F O   1 
ATOM   10941 C  CB  . GLU F 1 125 ? 77.547  84.252  43.831  1.00 24.37  ? 125 GLU F CB  1 
ATOM   10942 C  CG  . GLU F 1 125 ? 78.727  83.365  43.422  1.00 24.76  ? 125 GLU F CG  1 
ATOM   10943 C  CD  . GLU F 1 125 ? 79.402  82.650  44.596  1.00 28.02  ? 125 GLU F CD  1 
ATOM   10944 O  OE1 . GLU F 1 125 ? 78.833  82.581  45.716  1.00 23.20  ? 125 GLU F OE1 1 
ATOM   10945 O  OE2 . GLU F 1 125 ? 80.523  82.144  44.387  1.00 27.42  ? 125 GLU F OE2 1 
ATOM   10946 N  N   . TYR F 1 126 ? 78.523  87.132  43.138  1.00 26.78  ? 126 TYR F N   1 
ATOM   10947 C  CA  . TYR F 1 126 ? 79.418  88.068  42.470  1.00 28.60  ? 126 TYR F CA  1 
ATOM   10948 C  C   . TYR F 1 126 ? 80.113  88.974  43.478  1.00 29.03  ? 126 TYR F C   1 
ATOM   10949 O  O   . TYR F 1 126 ? 81.328  89.204  43.400  1.00 29.81  ? 126 TYR F O   1 
ATOM   10950 C  CB  . TYR F 1 126 ? 78.635  88.905  41.461  1.00 27.72  ? 126 TYR F CB  1 
ATOM   10951 C  CG  . TYR F 1 126 ? 79.500  89.893  40.714  1.00 29.16  ? 126 TYR F CG  1 
ATOM   10952 C  CD1 . TYR F 1 126 ? 80.253  89.490  39.615  1.00 33.41  ? 126 TYR F CD1 1 
ATOM   10953 C  CD2 . TYR F 1 126 ? 79.593  91.222  41.125  1.00 32.98  ? 126 TYR F CD2 1 
ATOM   10954 C  CE1 . TYR F 1 126 ? 81.054  90.390  38.931  1.00 35.99  ? 126 TYR F CE1 1 
ATOM   10955 C  CE2 . TYR F 1 126 ? 80.397  92.132  40.449  1.00 36.15  ? 126 TYR F CE2 1 
ATOM   10956 C  CZ  . TYR F 1 126 ? 81.124  91.711  39.353  1.00 41.00  ? 126 TYR F CZ  1 
ATOM   10957 O  OH  . TYR F 1 126 ? 81.925  92.608  38.670  1.00 43.06  ? 126 TYR F OH  1 
ATOM   10958 N  N   . GLU F 1 127 ? 79.352  89.497  44.438  1.00 26.78  ? 127 GLU F N   1 
ATOM   10959 C  CA  . GLU F 1 127 ? 79.918  90.425  45.409  1.00 27.52  ? 127 GLU F CA  1 
ATOM   10960 C  C   . GLU F 1 127 ? 80.848  89.711  46.382  1.00 29.12  ? 127 GLU F C   1 
ATOM   10961 O  O   . GLU F 1 127 ? 81.877  90.270  46.769  1.00 30.11  ? 127 GLU F O   1 
ATOM   10962 C  CB  . GLU F 1 127 ? 78.787  91.152  46.148  1.00 28.95  ? 127 GLU F CB  1 
ATOM   10963 C  CG  . GLU F 1 127 ? 78.059  92.190  45.269  1.00 23.51  ? 127 GLU F CG  1 
ATOM   10964 C  CD  . GLU F 1 127 ? 76.876  92.858  45.976  1.00 27.46  ? 127 GLU F CD  1 
ATOM   10965 O  OE1 . GLU F 1 127 ? 76.373  92.306  46.968  1.00 27.47  ? 127 GLU F OE1 1 
ATOM   10966 O  OE2 . GLU F 1 127 ? 76.447  93.938  45.541  1.00 31.08  ? 127 GLU F OE2 1 
ATOM   10967 N  N   . TYR F 1 128 ? 80.534  88.467  46.757  1.00 24.90  ? 128 TYR F N   1 
ATOM   10968 C  CA  . TYR F 1 128 ? 81.442  87.745  47.638  1.00 27.03  ? 128 TYR F CA  1 
ATOM   10969 C  C   . TYR F 1 128 ? 82.746  87.418  46.919  1.00 28.49  ? 128 TYR F C   1 
ATOM   10970 O  O   . TYR F 1 128 ? 83.832  87.585  47.492  1.00 25.99  ? 128 TYR F O   1 
ATOM   10971 C  CB  . TYR F 1 128 ? 80.783  86.473  48.175  1.00 24.63  ? 128 TYR F CB  1 
ATOM   10972 C  CG  . TYR F 1 128 ? 81.636  85.776  49.226  1.00 29.08  ? 128 TYR F CG  1 
ATOM   10973 C  CD1 . TYR F 1 128 ? 81.743  86.295  50.513  1.00 25.50  ? 128 TYR F CD1 1 
ATOM   10974 C  CD2 . TYR F 1 128 ? 82.362  84.616  48.921  1.00 27.16  ? 128 TYR F CD2 1 
ATOM   10975 C  CE1 . TYR F 1 128 ? 82.522  85.683  51.463  1.00 23.55  ? 128 TYR F CE1 1 
ATOM   10976 C  CE2 . TYR F 1 128 ? 83.148  83.999  49.868  1.00 26.32  ? 128 TYR F CE2 1 
ATOM   10977 C  CZ  . TYR F 1 128 ? 83.226  84.541  51.139  1.00 28.43  ? 128 TYR F CZ  1 
ATOM   10978 O  OH  . TYR F 1 128 ? 84.001  83.939  52.106  1.00 28.02  ? 128 TYR F OH  1 
ATOM   10979 N  N   . ALA F 1 129 ? 82.648  86.987  45.652  1.00 26.89  ? 129 ALA F N   1 
ATOM   10980 C  CA  . ALA F 1 129 ? 83.830  86.659  44.858  1.00 29.77  ? 129 ALA F CA  1 
ATOM   10981 C  C   . ALA F 1 129 ? 84.765  87.853  44.739  1.00 26.59  ? 129 ALA F C   1 
ATOM   10982 O  O   . ALA F 1 129 ? 85.987  87.690  44.755  1.00 29.20  ? 129 ALA F O   1 
ATOM   10983 C  CB  . ALA F 1 129 ? 83.416  86.171  43.463  1.00 26.62  ? 129 ALA F CB  1 
ATOM   10984 N  N   . MET F 1 130 ? 84.205  89.059  44.608  1.00 30.13  ? 130 MET F N   1 
ATOM   10985 C  CA  . MET F 1 130 ? 85.010  90.278  44.548  1.00 28.22  ? 130 MET F CA  1 
ATOM   10986 C  C   . MET F 1 130 ? 85.682  90.596  45.877  1.00 27.81  ? 130 MET F C   1 
ATOM   10987 O  O   . MET F 1 130 ? 86.738  91.228  45.890  1.00 30.54  ? 130 MET F O   1 
ATOM   10988 C  CB  . MET F 1 130 ? 84.155  91.470  44.119  1.00 29.95  ? 130 MET F CB  1 
ATOM   10989 C  CG  . MET F 1 130 ? 83.817  91.586  42.620  1.00 38.90  ? 130 MET F CG  1 
ATOM   10990 S  SD  . MET F 1 130 ? 85.118  91.216  41.399  1.00 39.55  ? 130 MET F SD  1 
ATOM   10991 C  CE  . MET F 1 130 ? 86.396  92.382  41.851  1.00 48.87  ? 130 MET F CE  1 
ATOM   10992 N  N   . ALA F 1 131 ? 85.105  90.170  47.000  1.00 30.55  ? 131 ALA F N   1 
ATOM   10993 C  CA  . ALA F 1 131 ? 85.624  90.513  48.330  1.00 28.95  ? 131 ALA F CA  1 
ATOM   10994 C  C   . ALA F 1 131 ? 85.476  89.329  49.279  1.00 28.93  ? 131 ALA F C   1 
ATOM   10995 O  O   . ALA F 1 131 ? 84.675  89.363  50.221  1.00 28.57  ? 131 ALA F O   1 
ATOM   10996 C  CB  . ALA F 1 131 ? 84.913  91.749  48.881  1.00 27.26  ? 131 ALA F CB  1 
ATOM   10997 N  N   . PRO F 1 132 ? 86.233  88.258  49.057  1.00 25.54  ? 132 PRO F N   1 
ATOM   10998 C  CA  . PRO F 1 132 ? 86.058  87.042  49.857  1.00 26.50  ? 132 PRO F CA  1 
ATOM   10999 C  C   . PRO F 1 132 ? 86.832  87.110  51.166  1.00 27.12  ? 132 PRO F C   1 
ATOM   11000 O  O   . PRO F 1 132 ? 87.636  88.013  51.402  1.00 30.45  ? 132 PRO F O   1 
ATOM   11001 C  CB  . PRO F 1 132 ? 86.624  85.943  48.948  1.00 31.24  ? 132 PRO F CB  1 
ATOM   11002 C  CG  . PRO F 1 132 ? 87.709  86.627  48.221  1.00 30.93  ? 132 PRO F CG  1 
ATOM   11003 C  CD  . PRO F 1 132 ? 87.221  88.057  47.985  1.00 28.68  ? 132 PRO F CD  1 
ATOM   11004 N  N   . ASP F 1 133 ? 86.581  86.117  52.019  1.00 22.23  ? 133 ASP F N   1 
ATOM   11005 C  CA  . ASP F 1 133 ? 87.361  85.952  53.238  1.00 26.87  ? 133 ASP F CA  1 
ATOM   11006 C  C   . ASP F 1 133 ? 88.627  85.153  52.949  1.00 29.89  ? 133 ASP F C   1 
ATOM   11007 O  O   . ASP F 1 133 ? 88.776  84.554  51.882  1.00 31.22  ? 133 ASP F O   1 
ATOM   11008 C  CB  . ASP F 1 133 ? 86.532  85.268  54.322  1.00 24.26  ? 133 ASP F CB  1 
ATOM   11009 C  CG  . ASP F 1 133 ? 85.290  86.053  54.650  1.00 26.50  ? 133 ASP F CG  1 
ATOM   11010 O  OD1 . ASP F 1 133 ? 85.402  87.058  55.388  1.00 25.81  ? 133 ASP F OD1 1 
ATOM   11011 O  OD2 . ASP F 1 133 ? 84.224  85.694  54.107  1.00 24.55  ? 133 ASP F OD2 1 
ATOM   11012 N  N   . TRP F 1 134 ? 89.542  85.138  53.926  1.00 27.43  ? 134 TRP F N   1 
ATOM   11013 C  CA  . TRP F 1 134 ? 90.850  84.532  53.686  1.00 30.14  ? 134 TRP F CA  1 
ATOM   11014 C  C   . TRP F 1 134 ? 90.729  83.056  53.352  1.00 29.23  ? 134 TRP F C   1 
ATOM   11015 O  O   . TRP F 1 134 ? 91.406  82.569  52.446  1.00 35.98  ? 134 TRP F O   1 
ATOM   11016 C  CB  . TRP F 1 134 ? 91.779  84.741  54.885  1.00 28.28  ? 134 TRP F CB  1 
ATOM   11017 C  CG  . TRP F 1 134 ? 91.378  84.024  56.167  1.00 30.88  ? 134 TRP F CG  1 
ATOM   11018 C  CD1 . TRP F 1 134 ? 90.704  84.562  57.229  1.00 26.26  ? 134 TRP F CD1 1 
ATOM   11019 C  CD2 . TRP F 1 134 ? 91.697  82.671  56.540  1.00 29.26  ? 134 TRP F CD2 1 
ATOM   11020 N  NE1 . TRP F 1 134 ? 90.558  83.618  58.223  1.00 31.27  ? 134 TRP F NE1 1 
ATOM   11021 C  CE2 . TRP F 1 134 ? 91.161  82.453  57.828  1.00 26.82  ? 134 TRP F CE2 1 
ATOM   11022 C  CE3 . TRP F 1 134 ? 92.380  81.623  55.907  1.00 29.73  ? 134 TRP F CE3 1 
ATOM   11023 C  CZ2 . TRP F 1 134 ? 91.279  81.228  58.489  1.00 30.04  ? 134 TRP F CZ2 1 
ATOM   11024 C  CZ3 . TRP F 1 134 ? 92.490  80.404  56.562  1.00 29.03  ? 134 TRP F CZ3 1 
ATOM   11025 C  CH2 . TRP F 1 134 ? 91.947  80.214  57.839  1.00 30.51  ? 134 TRP F CH2 1 
ATOM   11026 N  N   . PHE F 1 135 ? 89.862  82.327  54.052  1.00 32.37  ? 135 PHE F N   1 
ATOM   11027 C  CA  . PHE F 1 135 ? 89.795  80.882  53.834  1.00 32.52  ? 135 PHE F CA  1 
ATOM   11028 C  C   . PHE F 1 135 ? 89.284  80.503  52.442  1.00 33.69  ? 135 PHE F C   1 
ATOM   11029 O  O   . PHE F 1 135 ? 89.392  79.331  52.057  1.00 33.17  ? 135 PHE F O   1 
ATOM   11030 C  CB  . PHE F 1 135 ? 88.897  80.232  54.893  1.00 26.60  ? 135 PHE F CB  1 
ATOM   11031 C  CG  . PHE F 1 135 ? 87.430  80.456  54.653  1.00 30.91  ? 135 PHE F CG  1 
ATOM   11032 C  CD1 . PHE F 1 135 ? 86.807  81.616  55.114  1.00 28.00  ? 135 PHE F CD1 1 
ATOM   11033 C  CD2 . PHE F 1 135 ? 86.673  79.515  53.949  1.00 30.85  ? 135 PHE F CD2 1 
ATOM   11034 C  CE1 . PHE F 1 135 ? 85.460  81.837  54.882  1.00 29.10  ? 135 PHE F CE1 1 
ATOM   11035 C  CE2 . PHE F 1 135 ? 85.328  79.724  53.704  1.00 30.67  ? 135 PHE F CE2 1 
ATOM   11036 C  CZ  . PHE F 1 135 ? 84.711  80.883  54.175  1.00 28.12  ? 135 PHE F CZ  1 
ATOM   11037 N  N   . SER F 1 136 ? 88.695  81.439  51.699  1.00 31.35  ? 136 SER F N   1 
ATOM   11038 C  CA  . SER F 1 136 ? 88.043  81.112  50.439  1.00 33.64  ? 136 SER F CA  1 
ATOM   11039 C  C   . SER F 1 136 ? 88.573  81.923  49.273  1.00 30.08  ? 136 SER F C   1 
ATOM   11040 O  O   . SER F 1 136 ? 88.170  81.666  48.137  1.00 31.35  ? 136 SER F O   1 
ATOM   11041 C  CB  . SER F 1 136 ? 86.521  81.311  50.547  1.00 30.69  ? 136 SER F CB  1 
ATOM   11042 O  OG  . SER F 1 136 ? 86.218  82.630  50.972  1.00 34.49  ? 136 SER F OG  1 
ATOM   11043 N  N   . ALA F 1 137 ? 89.453  82.898  49.517  1.00 28.27  ? 137 ALA F N   1 
ATOM   11044 C  CA  . ALA F 1 137 ? 89.900  83.773  48.434  1.00 33.58  ? 137 ALA F CA  1 
ATOM   11045 C  C   . ALA F 1 137 ? 90.582  82.978  47.328  1.00 33.75  ? 137 ALA F C   1 
ATOM   11046 O  O   . ALA F 1 137 ? 90.385  83.263  46.138  1.00 33.09  ? 137 ALA F O   1 
ATOM   11047 C  CB  . ALA F 1 137 ? 90.843  84.853  48.968  1.00 27.19  ? 137 ALA F CB  1 
ATOM   11048 N  N   . GLY F 1 138 ? 91.383  81.976  47.704  1.00 31.74  ? 138 GLY F N   1 
ATOM   11049 C  CA  . GLY F 1 138 ? 92.089  81.154  46.735  1.00 32.85  ? 138 GLY F CA  1 
ATOM   11050 C  C   . GLY F 1 138 ? 91.175  80.425  45.777  1.00 37.12  ? 138 GLY F C   1 
ATOM   11051 O  O   . GLY F 1 138 ? 91.585  80.122  44.649  1.00 34.67  ? 138 GLY F O   1 
ATOM   11052 N  N   . GLY F 1 139 ? 89.933  80.164  46.193  1.00 32.97  ? 139 GLY F N   1 
ATOM   11053 C  CA  . GLY F 1 139 ? 88.961  79.498  45.361  1.00 29.99  ? 139 GLY F CA  1 
ATOM   11054 C  C   . GLY F 1 139 ? 88.291  80.363  44.324  1.00 31.43  ? 139 GLY F C   1 
ATOM   11055 O  O   . GLY F 1 139 ? 87.521  79.836  43.515  1.00 34.91  ? 139 GLY F O   1 
ATOM   11056 N  N   . TYR F 1 140 ? 88.558  81.664  44.321  1.00 29.52  ? 140 TYR F N   1 
ATOM   11057 C  CA  . TYR F 1 140 ? 87.998  82.592  43.343  1.00 32.35  ? 140 TYR F CA  1 
ATOM   11058 C  C   . TYR F 1 140 ? 89.122  83.128  42.461  1.00 36.76  ? 140 TYR F C   1 
ATOM   11059 O  O   . TYR F 1 140 ? 90.044  83.777  42.963  1.00 35.55  ? 140 TYR F O   1 
ATOM   11060 C  CB  . TYR F 1 140 ? 87.263  83.742  44.042  1.00 30.58  ? 140 TYR F CB  1 
ATOM   11061 C  CG  . TYR F 1 140 ? 85.949  83.332  44.695  1.00 30.92  ? 140 TYR F CG  1 
ATOM   11062 C  CD1 . TYR F 1 140 ? 84.813  83.077  43.927  1.00 28.91  ? 140 TYR F CD1 1 
ATOM   11063 C  CD2 . TYR F 1 140 ? 85.852  83.192  46.076  1.00 27.43  ? 140 TYR F CD2 1 
ATOM   11064 C  CE1 . TYR F 1 140 ? 83.614  82.694  44.521  1.00 30.47  ? 140 TYR F CE1 1 
ATOM   11065 C  CE2 . TYR F 1 140 ? 84.665  82.817  46.678  1.00 27.72  ? 140 TYR F CE2 1 
ATOM   11066 C  CZ  . TYR F 1 140 ? 83.544  82.572  45.900  1.00 27.81  ? 140 TYR F CZ  1 
ATOM   11067 O  OH  . TYR F 1 140 ? 82.362  82.195  46.507  1.00 28.14  ? 140 TYR F OH  1 
ATOM   11068 N  N   . ILE F 1 141 ? 89.027  82.882  41.150  1.00 39.11  ? 141 ILE F N   1 
ATOM   11069 C  CA  . ILE F 1 141 ? 90.065  83.238  40.180  1.00 38.14  ? 141 ILE F CA  1 
ATOM   11070 C  C   . ILE F 1 141 ? 89.618  84.503  39.460  1.00 39.43  ? 141 ILE F C   1 
ATOM   11071 O  O   . ILE F 1 141 ? 88.858  84.436  38.491  1.00 37.71  ? 141 ILE F O   1 
ATOM   11072 C  CB  . ILE F 1 141 ? 90.324  82.105  39.180  1.00 37.88  ? 141 ILE F CB  1 
ATOM   11073 C  CG1 . ILE F 1 141 ? 90.644  80.790  39.900  1.00 33.84  ? 141 ILE F CG1 1 
ATOM   11074 C  CG2 . ILE F 1 141 ? 91.435  82.479  38.216  1.00 38.51  ? 141 ILE F CG2 1 
ATOM   11075 C  CD1 . ILE F 1 141 ? 91.763  80.886  40.917  1.00 36.78  ? 141 ILE F CD1 1 
ATOM   11076 N  N   . ARG F 1 142 ? 90.123  85.655  39.916  1.00 39.23  ? 142 ARG F N   1 
ATOM   11077 C  CA  . ARG F 1 142 ? 89.746  86.940  39.340  1.00 40.44  ? 142 ARG F CA  1 
ATOM   11078 C  C   . ARG F 1 142 ? 90.021  87.005  37.840  1.00 45.41  ? 142 ARG F C   1 
ATOM   11079 O  O   . ARG F 1 142 ? 89.328  87.735  37.116  1.00 42.53  ? 142 ARG F O   1 
ATOM   11080 C  CB  . ARG F 1 142 ? 90.497  88.066  40.051  1.00 47.29  ? 142 ARG F CB  1 
ATOM   11081 C  CG  . ARG F 1 142 ? 89.963  88.422  41.433  1.00 51.81  ? 142 ARG F CG  1 
ATOM   11082 C  CD  . ARG F 1 142 ? 89.178  89.733  41.387  1.00 54.92  ? 142 ARG F CD  1 
ATOM   11083 N  NE  . ARG F 1 142 ? 89.978  90.880  41.805  1.00 59.62  ? 142 ARG F NE  1 
ATOM   11084 C  CZ  . ARG F 1 142 ? 90.418  91.081  43.041  1.00 62.52  ? 142 ARG F CZ  1 
ATOM   11085 N  NH1 . ARG F 1 142 ? 90.084  90.273  44.034  1.00 60.09  ? 142 ARG F NH1 1 
ATOM   11086 N  NH2 . ARG F 1 142 ? 91.204  92.128  43.290  1.00 63.17  ? 142 ARG F NH2 1 
ATOM   11087 N  N   . ALA F 1 143 ? 91.033  86.273  37.358  1.00 44.77  ? 143 ALA F N   1 
ATOM   11088 C  CA  . ALA F 1 143 ? 91.299  86.247  35.922  1.00 48.17  ? 143 ALA F CA  1 
ATOM   11089 C  C   . ALA F 1 143 ? 90.116  85.675  35.149  1.00 44.03  ? 143 ALA F C   1 
ATOM   11090 O  O   . ALA F 1 143 ? 89.911  86.020  33.979  1.00 45.71  ? 143 ALA F O   1 
ATOM   11091 C  CB  . ALA F 1 143 ? 92.574  85.448  35.628  1.00 39.10  ? 143 ALA F CB  1 
ATOM   11092 N  N   . ASP F 1 144 ? 89.322  84.815  35.781  1.00 41.74  ? 144 ASP F N   1 
ATOM   11093 C  CA  . ASP F 1 144 ? 88.136  84.302  35.107  1.00 40.92  ? 144 ASP F CA  1 
ATOM   11094 C  C   . ASP F 1 144 ? 86.990  85.317  35.111  1.00 42.91  ? 144 ASP F C   1 
ATOM   11095 O  O   . ASP F 1 144 ? 86.456  85.663  34.053  1.00 43.27  ? 144 ASP F O   1 
ATOM   11096 C  CB  . ASP F 1 144 ? 87.706  82.981  35.748  1.00 38.04  ? 144 ASP F CB  1 
ATOM   11097 C  CG  . ASP F 1 144 ? 88.493  81.793  35.215  1.00 44.57  ? 144 ASP F CG  1 
ATOM   11098 O  OD1 . ASP F 1 144 ? 89.283  81.998  34.261  1.00 48.47  ? 144 ASP F OD1 1 
ATOM   11099 O  OD2 . ASP F 1 144 ? 88.335  80.664  35.740  1.00 38.77  ? 144 ASP F OD2 1 
ATOM   11100 N  N   . PHE F 1 145 ? 86.603  85.825  36.286  1.00 41.70  ? 145 PHE F N   1 
ATOM   11101 C  CA  . PHE F 1 145 ? 85.319  86.518  36.390  1.00 37.27  ? 145 PHE F CA  1 
ATOM   11102 C  C   . PHE F 1 145 ? 85.422  88.041  36.493  1.00 37.86  ? 145 PHE F C   1 
ATOM   11103 O  O   . PHE F 1 145 ? 84.403  88.721  36.348  1.00 37.02  ? 145 PHE F O   1 
ATOM   11104 C  CB  . PHE F 1 145 ? 84.510  85.959  37.579  1.00 33.16  ? 145 PHE F CB  1 
ATOM   11105 C  CG  . PHE F 1 145 ? 85.153  86.175  38.937  1.00 34.46  ? 145 PHE F CG  1 
ATOM   11106 C  CD1 . PHE F 1 145 ? 85.073  87.401  39.583  1.00 32.67  ? 145 PHE F CD1 1 
ATOM   11107 C  CD2 . PHE F 1 145 ? 85.802  85.136  39.581  1.00 35.28  ? 145 PHE F CD2 1 
ATOM   11108 C  CE1 . PHE F 1 145 ? 85.659  87.597  40.833  1.00 34.11  ? 145 PHE F CE1 1 
ATOM   11109 C  CE2 . PHE F 1 145 ? 86.389  85.324  40.831  1.00 34.61  ? 145 PHE F CE2 1 
ATOM   11110 C  CZ  . PHE F 1 145 ? 86.313  86.559  41.458  1.00 35.30  ? 145 PHE F CZ  1 
ATOM   11111 N  N   . ASP F 1 146 ? 86.606  88.602  36.714  1.00 42.22  ? 146 ASP F N   1 
ATOM   11112 C  CA  . ASP F 1 146 ? 86.750  90.053  36.828  1.00 43.92  ? 146 ASP F CA  1 
ATOM   11113 C  C   . ASP F 1 146 ? 87.252  90.624  35.501  1.00 48.09  ? 146 ASP F C   1 
ATOM   11114 O  O   . ASP F 1 146 ? 88.411  91.022  35.342  1.00 46.76  ? 146 ASP F O   1 
ATOM   11115 C  CB  . ASP F 1 146 ? 87.678  90.405  37.992  1.00 44.61  ? 146 ASP F CB  1 
ATOM   11116 C  CG  . ASP F 1 146 ? 87.740  91.903  38.271  1.00 45.66  ? 146 ASP F CG  1 
ATOM   11117 O  OD1 . ASP F 1 146 ? 86.949  92.664  37.680  1.00 47.04  ? 146 ASP F OD1 1 
ATOM   11118 O  OD2 . ASP F 1 146 ? 88.588  92.323  39.089  1.00 51.40  ? 146 ASP F OD2 1 
ATOM   11119 N  N   . ARG F 1 147 ? 86.333  90.662  34.538  1.00 48.42  ? 147 ARG F N   1 
ATOM   11120 C  CA  . ARG F 1 147 ? 86.606  91.154  33.190  1.00 52.46  ? 147 ARG F CA  1 
ATOM   11121 C  C   . ARG F 1 147 ? 85.585  92.235  32.882  1.00 51.41  ? 147 ARG F C   1 
ATOM   11122 O  O   . ARG F 1 147 ? 84.367  91.974  32.958  1.00 49.68  ? 147 ARG F O   1 
ATOM   11123 C  CB  . ARG F 1 147 ? 86.535  90.030  32.152  1.00 49.19  ? 147 ARG F CB  1 
ATOM   11124 C  CG  . ARG F 1 147 ? 87.437  88.837  32.433  1.00 47.33  ? 147 ARG F CG  1 
ATOM   11125 C  CD  . ARG F 1 147 ? 87.055  87.659  31.546  1.00 48.05  ? 147 ARG F CD  1 
ATOM   11126 N  NE  . ARG F 1 147 ? 87.947  86.514  31.688  1.00 48.27  ? 147 ARG F NE  1 
ATOM   11127 C  CZ  . ARG F 1 147 ? 88.472  85.843  30.669  1.00 54.11  ? 147 ARG F CZ  1 
ATOM   11128 N  NH1 . ARG F 1 147 ? 88.244  86.203  29.410  1.00 51.92  ? 147 ARG F NH1 1 
ATOM   11129 N  NH2 . ARG F 1 147 ? 89.246  84.786  30.917  1.00 46.32  ? 147 ARG F NH2 1 
ATOM   11130 N  N   . PRO F 1 148 ? 86.009  93.453  32.535  1.00 58.45  ? 148 PRO F N   1 
ATOM   11131 C  CA  . PRO F 1 148 ? 85.041  94.552  32.371  1.00 60.45  ? 148 PRO F CA  1 
ATOM   11132 C  C   . PRO F 1 148 ? 84.107  94.398  31.175  1.00 58.53  ? 148 PRO F C   1 
ATOM   11133 O  O   . PRO F 1 148 ? 83.094  95.106  31.117  1.00 56.16  ? 148 PRO F O   1 
ATOM   11134 C  CB  . PRO F 1 148 ? 85.939  95.789  32.222  1.00 60.16  ? 148 PRO F CB  1 
ATOM   11135 C  CG  . PRO F 1 148 ? 87.226  95.391  32.909  1.00 62.07  ? 148 PRO F CG  1 
ATOM   11136 C  CD  . PRO F 1 148 ? 87.398  93.941  32.547  1.00 54.38  ? 148 PRO F CD  1 
ATOM   11137 N  N   . ASP F 1 149 ? 84.402  93.495  30.235  1.00 59.31  ? 149 ASP F N   1 
ATOM   11138 C  CA  . ASP F 1 149 ? 83.585  93.306  29.039  1.00 55.04  ? 149 ASP F CA  1 
ATOM   11139 C  C   . ASP F 1 149 ? 82.314  92.500  29.287  1.00 52.13  ? 149 ASP F C   1 
ATOM   11140 O  O   . ASP F 1 149 ? 81.445  92.461  28.409  1.00 50.12  ? 149 ASP F O   1 
ATOM   11141 C  CB  . ASP F 1 149 ? 84.411  92.603  27.957  1.00 58.89  ? 149 ASP F CB  1 
ATOM   11142 C  CG  . ASP F 1 149 ? 85.235  91.442  28.515  1.00 58.46  ? 149 ASP F CG  1 
ATOM   11143 O  OD1 . ASP F 1 149 ? 86.071  91.699  29.411  1.00 55.84  ? 149 ASP F OD1 1 
ATOM   11144 O  OD2 . ASP F 1 149 ? 85.046  90.284  28.063  1.00 53.41  ? 149 ASP F OD2 1 
ATOM   11145 N  N   . VAL F 1 150 ? 82.180  91.863  30.447  1.00 52.54  ? 150 VAL F N   1 
ATOM   11146 C  CA  . VAL F 1 150 ? 81.149  90.850  30.659  1.00 48.94  ? 150 VAL F CA  1 
ATOM   11147 C  C   . VAL F 1 150 ? 79.804  91.514  30.939  1.00 44.79  ? 150 VAL F C   1 
ATOM   11148 O  O   . VAL F 1 150 ? 79.703  92.428  31.764  1.00 44.00  ? 150 VAL F O   1 
ATOM   11149 C  CB  . VAL F 1 150 ? 81.556  89.909  31.805  1.00 46.89  ? 150 VAL F CB  1 
ATOM   11150 C  CG1 . VAL F 1 150 ? 80.430  88.924  32.133  1.00 39.51  ? 150 VAL F CG1 1 
ATOM   11151 C  CG2 . VAL F 1 150 ? 82.847  89.178  31.450  1.00 45.91  ? 150 VAL F CG2 1 
ATOM   11152 N  N   . LYS F 1 151 ? 78.764  91.058  30.245  1.00 42.99  ? 151 LYS F N   1 
ATOM   11153 C  CA  . LYS F 1 151 ? 77.397  91.467  30.545  1.00 45.09  ? 151 LYS F CA  1 
ATOM   11154 C  C   . LYS F 1 151 ? 76.856  90.584  31.665  1.00 42.05  ? 151 LYS F C   1 
ATOM   11155 O  O   . LYS F 1 151 ? 76.750  89.364  31.501  1.00 38.19  ? 151 LYS F O   1 
ATOM   11156 C  CB  . LYS F 1 151 ? 76.506  91.354  29.310  1.00 47.08  ? 151 LYS F CB  1 
ATOM   11157 C  CG  . LYS F 1 151 ? 76.749  92.398  28.250  1.00 58.23  ? 151 LYS F CG  1 
ATOM   11158 C  CD  . LYS F 1 151 ? 75.541  93.323  28.127  1.00 71.61  ? 151 LYS F CD  1 
ATOM   11159 C  CE  . LYS F 1 151 ? 75.140  93.540  26.674  1.00 79.87  ? 151 LYS F CE  1 
ATOM   11160 N  NZ  . LYS F 1 151 ? 74.005  94.501  26.561  1.00 82.60  ? 151 LYS F NZ  1 
ATOM   11161 N  N   . TRP F 1 152 ? 76.510  91.193  32.794  1.00 38.77  ? 152 TRP F N   1 
ATOM   11162 C  CA  . TRP F 1 152 ? 76.018  90.457  33.949  1.00 33.79  ? 152 TRP F CA  1 
ATOM   11163 C  C   . TRP F 1 152 ? 74.540  90.741  34.181  1.00 31.74  ? 152 TRP F C   1 
ATOM   11164 O  O   . TRP F 1 152 ? 74.091  91.889  34.094  1.00 35.30  ? 152 TRP F O   1 
ATOM   11165 C  CB  . TRP F 1 152 ? 76.788  90.830  35.216  1.00 31.73  ? 152 TRP F CB  1 
ATOM   11166 C  CG  . TRP F 1 152 ? 78.192  90.354  35.305  1.00 29.61  ? 152 TRP F CG  1 
ATOM   11167 C  CD1 . TRP F 1 152 ? 79.313  91.098  35.109  1.00 34.29  ? 152 TRP F CD1 1 
ATOM   11168 C  CD2 . TRP F 1 152 ? 78.640  89.041  35.673  1.00 33.53  ? 152 TRP F CD2 1 
ATOM   11169 N  NE1 . TRP F 1 152 ? 80.434  90.332  35.309  1.00 36.58  ? 152 TRP F NE1 1 
ATOM   11170 C  CE2 . TRP F 1 152 ? 80.052  89.063  35.652  1.00 31.04  ? 152 TRP F CE2 1 
ATOM   11171 C  CE3 . TRP F 1 152 ? 77.985  87.846  36.006  1.00 26.50  ? 152 TRP F CE3 1 
ATOM   11172 C  CZ2 . TRP F 1 152 ? 80.824  87.944  35.951  1.00 31.78  ? 152 TRP F CZ2 1 
ATOM   11173 C  CZ3 . TRP F 1 152 ? 78.750  86.736  36.299  1.00 28.25  ? 152 TRP F CZ3 1 
ATOM   11174 C  CH2 . TRP F 1 152 ? 80.160  86.792  36.274  1.00 31.73  ? 152 TRP F CH2 1 
ATOM   11175 N  N   . HIS F 1 153 ? 73.793  89.692  34.495  1.00 27.44  ? 153 HIS F N   1 
ATOM   11176 C  CA  . HIS F 1 153 ? 72.480  89.805  35.111  1.00 29.76  ? 153 HIS F CA  1 
ATOM   11177 C  C   . HIS F 1 153 ? 72.619  89.245  36.529  1.00 30.59  ? 153 HIS F C   1 
ATOM   11178 O  O   . HIS F 1 153 ? 72.799  88.036  36.707  1.00 26.51  ? 153 HIS F O   1 
ATOM   11179 C  CB  . HIS F 1 153 ? 71.425  89.054  34.299  1.00 29.09  ? 153 HIS F CB  1 
ATOM   11180 C  CG  . HIS F 1 153 ? 70.063  89.055  34.923  1.00 30.87  ? 153 HIS F CG  1 
ATOM   11181 N  ND1 . HIS F 1 153 ? 69.645  90.034  35.801  1.00 30.80  ? 153 HIS F ND1 1 
ATOM   11182 C  CD2 . HIS F 1 153 ? 69.019  88.202  34.788  1.00 31.31  ? 153 HIS F CD2 1 
ATOM   11183 C  CE1 . HIS F 1 153 ? 68.406  89.786  36.183  1.00 29.53  ? 153 HIS F CE1 1 
ATOM   11184 N  NE2 . HIS F 1 153 ? 68.001  88.680  35.585  1.00 32.81  ? 153 HIS F NE2 1 
ATOM   11185 N  N   . LEU F 1 154 ? 72.578  90.123  37.532  1.00 25.59  ? 154 LEU F N   1 
ATOM   11186 C  CA  . LEU F 1 154 ? 72.857  89.741  38.916  1.00 28.58  ? 154 LEU F CA  1 
ATOM   11187 C  C   . LEU F 1 154 ? 71.512  89.537  39.619  1.00 29.22  ? 154 LEU F C   1 
ATOM   11188 O  O   . LEU F 1 154 ? 70.760  90.496  39.829  1.00 27.00  ? 154 LEU F O   1 
ATOM   11189 C  CB  . LEU F 1 154 ? 73.720  90.792  39.620  1.00 24.65  ? 154 LEU F CB  1 
ATOM   11190 C  CG  . LEU F 1 154 ? 75.167  90.984  39.115  1.00 27.21  ? 154 LEU F CG  1 
ATOM   11191 C  CD1 . LEU F 1 154 ? 76.004  91.868  40.031  1.00 28.40  ? 154 LEU F CD1 1 
ATOM   11192 C  CD2 . LEU F 1 154 ? 75.907  89.637  38.874  1.00 23.85  ? 154 LEU F CD2 1 
ATOM   11193 N  N   . LEU F 1 155 ? 71.205  88.281  39.947  1.00 25.16  ? 155 LEU F N   1 
ATOM   11194 C  CA  . LEU F 1 155 ? 69.927  87.939  40.558  1.00 27.68  ? 155 LEU F CA  1 
ATOM   11195 C  C   . LEU F 1 155 ? 69.883  88.366  42.018  1.00 29.73  ? 155 LEU F C   1 
ATOM   11196 O  O   . LEU F 1 155 ? 70.889  88.286  42.735  1.00 27.69  ? 155 LEU F O   1 
ATOM   11197 C  CB  . LEU F 1 155 ? 69.693  86.433  40.468  1.00 27.65  ? 155 LEU F CB  1 
ATOM   11198 C  CG  . LEU F 1 155 ? 69.680  85.821  39.061  1.00 31.79  ? 155 LEU F CG  1 
ATOM   11199 C  CD1 . LEU F 1 155 ? 69.482  84.305  39.133  1.00 23.14  ? 155 LEU F CD1 1 
ATOM   11200 C  CD2 . LEU F 1 155 ? 68.578  86.478  38.186  1.00 25.99  ? 155 LEU F CD2 1 
ATOM   11201 N  N   . GLU F 1 156 ? 68.698  88.774  42.463  1.00 29.46  ? 156 GLU F N   1 
ATOM   11202 C  CA  . GLU F 1 156 ? 68.440  89.190  43.835  1.00 30.86  ? 156 GLU F CA  1 
ATOM   11203 C  C   . GLU F 1 156 ? 67.827  88.046  44.638  1.00 32.88  ? 156 GLU F C   1 
ATOM   11204 O  O   . GLU F 1 156 ? 67.467  86.993  44.103  1.00 30.48  ? 156 GLU F O   1 
ATOM   11205 C  CB  . GLU F 1 156 ? 67.506  90.407  43.870  1.00 30.22  ? 156 GLU F CB  1 
ATOM   11206 C  CG  . GLU F 1 156 ? 68.005  91.606  43.075  1.00 32.11  ? 156 GLU F CG  1 
ATOM   11207 C  CD  . GLU F 1 156 ? 69.151  92.320  43.768  1.00 35.16  ? 156 GLU F CD  1 
ATOM   11208 O  OE1 . GLU F 1 156 ? 69.473  91.943  44.914  1.00 38.86  ? 156 GLU F OE1 1 
ATOM   11209 O  OE2 . GLU F 1 156 ? 69.739  93.248  43.173  1.00 33.22  ? 156 GLU F OE2 1 
ATOM   11210 N  N   . GLY F 1 157 ? 67.682  88.287  45.948  1.00 38.37  ? 157 GLY F N   1 
ATOM   11211 C  CA  . GLY F 1 157 ? 67.158  87.257  46.839  1.00 35.96  ? 157 GLY F CA  1 
ATOM   11212 C  C   . GLY F 1 157 ? 65.783  86.756  46.437  1.00 38.92  ? 157 GLY F C   1 
ATOM   11213 O  O   . GLY F 1 157 ? 65.486  85.566  46.560  1.00 42.50  ? 157 GLY F O   1 
ATOM   11214 N  N   . HIS F 1 158 ? 64.937  87.648  45.924  1.00 37.84  ? 158 HIS F N   1 
ATOM   11215 C  CA  . HIS F 1 158 ? 63.589  87.280  45.517  1.00 39.32  ? 158 HIS F CA  1 
ATOM   11216 C  C   . HIS F 1 158 ? 63.537  86.592  44.157  1.00 38.81  ? 158 HIS F C   1 
ATOM   11217 O  O   . HIS F 1 158 ? 62.443  86.274  43.674  1.00 35.97  ? 158 HIS F O   1 
ATOM   11218 C  CB  . HIS F 1 158 ? 62.694  88.520  45.507  1.00 41.69  ? 158 HIS F CB  1 
ATOM   11219 C  CG  . HIS F 1 158 ? 62.412  89.058  46.877  1.00 51.50  ? 158 HIS F CG  1 
ATOM   11220 N  ND1 . HIS F 1 158 ? 63.179  90.045  47.463  1.00 59.68  ? 158 HIS F ND1 1 
ATOM   11221 C  CD2 . HIS F 1 158 ? 61.469  88.725  47.789  1.00 51.25  ? 158 HIS F CD2 1 
ATOM   11222 C  CE1 . HIS F 1 158 ? 62.706  90.310  48.669  1.00 53.63  ? 158 HIS F CE1 1 
ATOM   11223 N  NE2 . HIS F 1 158 ? 61.669  89.522  48.892  1.00 55.50  ? 158 HIS F NE2 1 
ATOM   11224 N  N   . ASP F 1 159 ? 64.677  86.347  43.530  1.00 34.96  ? 159 ASP F N   1 
ATOM   11225 C  CA  . ASP F 1 159 ? 64.698  85.773  42.198  1.00 32.97  ? 159 ASP F CA  1 
ATOM   11226 C  C   . ASP F 1 159 ? 64.822  84.261  42.209  1.00 31.33  ? 159 ASP F C   1 
ATOM   11227 O  O   . ASP F 1 159 ? 65.125  83.673  41.163  1.00 27.64  ? 159 ASP F O   1 
ATOM   11228 C  CB  . ASP F 1 159 ? 65.837  86.383  41.387  1.00 28.55  ? 159 ASP F CB  1 
ATOM   11229 C  CG  . ASP F 1 159 ? 65.519  87.769  40.930  1.00 30.95  ? 159 ASP F CG  1 
ATOM   11230 O  OD1 . ASP F 1 159 ? 64.328  88.002  40.639  1.00 36.12  ? 159 ASP F OD1 1 
ATOM   11231 O  OD2 . ASP F 1 159 ? 66.429  88.631  40.885  1.00 28.34  ? 159 ASP F OD2 1 
ATOM   11232 N  N   . ASP F 1 160 ? 64.619  83.624  43.365  1.00 29.68  ? 160 ASP F N   1 
ATOM   11233 C  CA  . ASP F 1 160 ? 64.651  82.171  43.428  1.00 30.53  ? 160 ASP F CA  1 
ATOM   11234 C  C   . ASP F 1 160 ? 63.613  81.615  42.459  1.00 27.82  ? 160 ASP F C   1 
ATOM   11235 O  O   . ASP F 1 160 ? 62.504  82.138  42.353  1.00 26.63  ? 160 ASP F O   1 
ATOM   11236 C  CB  . ASP F 1 160 ? 64.389  81.705  44.860  1.00 25.81  ? 160 ASP F CB  1 
ATOM   11237 C  CG  . ASP F 1 160 ? 64.779  80.246  45.099  1.00 33.38  ? 160 ASP F CG  1 
ATOM   11238 O  OD1 . ASP F 1 160 ? 65.371  79.600  44.201  1.00 30.26  ? 160 ASP F OD1 1 
ATOM   11239 O  OD2 . ASP F 1 160 ? 64.508  79.744  46.214  1.00 35.04  ? 160 ASP F OD2 1 
ATOM   11240 N  N   . GLY F 1 161 ? 63.992  80.571  41.721  1.00 27.89  ? 161 GLY F N   1 
ATOM   11241 C  CA  . GLY F 1 161 ? 63.159  80.045  40.662  1.00 23.71  ? 161 GLY F CA  1 
ATOM   11242 C  C   . GLY F 1 161 ? 63.390  80.644  39.284  1.00 31.41  ? 161 GLY F C   1 
ATOM   11243 O  O   . GLY F 1 161 ? 62.724  80.210  38.332  1.00 31.64  ? 161 GLY F O   1 
ATOM   11244 N  N   . TYR F 1 162 ? 64.319  81.600  39.134  1.00 24.20  ? 162 TYR F N   1 
ATOM   11245 C  CA  . TYR F 1 162 ? 64.416  82.382  37.894  1.00 26.43  ? 162 TYR F CA  1 
ATOM   11246 C  C   . TYR F 1 162 ? 64.418  81.489  36.650  1.00 27.81  ? 162 TYR F C   1 
ATOM   11247 O  O   . TYR F 1 162 ? 65.232  80.571  36.525  1.00 27.79  ? 162 TYR F O   1 
ATOM   11248 C  CB  . TYR F 1 162 ? 65.668  83.264  37.912  1.00 23.11  ? 162 TYR F CB  1 
ATOM   11249 C  CG  . TYR F 1 162 ? 65.740  84.220  36.744  1.00 28.93  ? 162 TYR F CG  1 
ATOM   11250 C  CD1 . TYR F 1 162 ? 65.089  85.455  36.774  1.00 25.42  ? 162 TYR F CD1 1 
ATOM   11251 C  CD2 . TYR F 1 162 ? 66.444  83.876  35.594  1.00 27.02  ? 162 TYR F CD2 1 
ATOM   11252 C  CE1 . TYR F 1 162 ? 65.158  86.318  35.688  1.00 26.72  ? 162 TYR F CE1 1 
ATOM   11253 C  CE2 . TYR F 1 162 ? 66.523  84.714  34.523  1.00 23.53  ? 162 TYR F CE2 1 
ATOM   11254 C  CZ  . TYR F 1 162 ? 65.886  85.931  34.557  1.00 27.60  ? 162 TYR F CZ  1 
ATOM   11255 O  OH  . TYR F 1 162 ? 65.986  86.747  33.451  1.00 27.37  ? 162 TYR F OH  1 
ATOM   11256 N  N   . ASP F 1 163 ? 63.489  81.771  35.737  1.00 29.39  ? 163 ASP F N   1 
ATOM   11257 C  CA  . ASP F 1 163 ? 63.250  80.982  34.528  1.00 29.48  ? 163 ASP F CA  1 
ATOM   11258 C  C   . ASP F 1 163 ? 63.992  81.632  33.357  1.00 28.72  ? 163 ASP F C   1 
ATOM   11259 O  O   . ASP F 1 163 ? 63.619  82.722  32.909  1.00 26.85  ? 163 ASP F O   1 
ATOM   11260 C  CB  . ASP F 1 163 ? 61.747  80.913  34.261  1.00 31.81  ? 163 ASP F CB  1 
ATOM   11261 C  CG  . ASP F 1 163 ? 61.367  79.850  33.227  1.00 35.48  ? 163 ASP F CG  1 
ATOM   11262 O  OD1 . ASP F 1 163 ? 62.135  79.614  32.259  1.00 34.36  ? 163 ASP F OD1 1 
ATOM   11263 O  OD2 . ASP F 1 163 ? 60.290  79.249  33.394  1.00 33.67  ? 163 ASP F OD2 1 
ATOM   11264 N  N   . VAL F 1 164 ? 65.039  80.966  32.858  1.00 29.61  ? 164 VAL F N   1 
ATOM   11265 C  CA  . VAL F 1 164 ? 65.927  81.606  31.883  1.00 27.28  ? 164 VAL F CA  1 
ATOM   11266 C  C   . VAL F 1 164 ? 65.145  82.058  30.651  1.00 31.42  ? 164 VAL F C   1 
ATOM   11267 O  O   . VAL F 1 164 ? 65.200  83.228  30.253  1.00 30.20  ? 164 VAL F O   1 
ATOM   11268 C  CB  . VAL F 1 164 ? 67.084  80.666  31.505  1.00 26.37  ? 164 VAL F CB  1 
ATOM   11269 C  CG1 . VAL F 1 164 ? 67.839  81.227  30.317  1.00 30.06  ? 164 VAL F CG1 1 
ATOM   11270 C  CG2 . VAL F 1 164 ? 68.034  80.484  32.695  1.00 29.41  ? 164 VAL F CG2 1 
ATOM   11271 N  N   . PHE F 1 165 ? 64.394  81.140  30.039  1.00 33.99  ? 165 PHE F N   1 
ATOM   11272 C  CA  . PHE F 1 165 ? 63.658  81.411  28.810  1.00 31.24  ? 165 PHE F CA  1 
ATOM   11273 C  C   . PHE F 1 165 ? 62.195  81.754  29.049  1.00 35.90  ? 165 PHE F C   1 
ATOM   11274 O  O   . PHE F 1 165 ? 61.514  82.194  28.117  1.00 38.98  ? 165 PHE F O   1 
ATOM   11275 C  CB  . PHE F 1 165 ? 63.740  80.201  27.862  1.00 36.95  ? 165 PHE F CB  1 
ATOM   11276 C  CG  . PHE F 1 165 ? 65.117  79.946  27.316  1.00 33.71  ? 165 PHE F CG  1 
ATOM   11277 C  CD1 . PHE F 1 165 ? 65.713  80.853  26.451  1.00 34.25  ? 165 PHE F CD1 1 
ATOM   11278 C  CD2 . PHE F 1 165 ? 65.809  78.790  27.655  1.00 33.30  ? 165 PHE F CD2 1 
ATOM   11279 C  CE1 . PHE F 1 165 ? 66.985  80.620  25.944  1.00 34.86  ? 165 PHE F CE1 1 
ATOM   11280 C  CE2 . PHE F 1 165 ? 67.083  78.541  27.145  1.00 34.67  ? 165 PHE F CE2 1 
ATOM   11281 C  CZ  . PHE F 1 165 ? 67.669  79.462  26.287  1.00 34.00  ? 165 PHE F CZ  1 
ATOM   11282 N  N   . GLY F 1 166 ? 61.693  81.575  30.263  1.00 34.95  ? 166 GLY F N   1 
ATOM   11283 C  CA  . GLY F 1 166 ? 60.280  81.774  30.489  1.00 32.81  ? 166 GLY F CA  1 
ATOM   11284 C  C   . GLY F 1 166 ? 59.407  80.609  30.073  1.00 40.14  ? 166 GLY F C   1 
ATOM   11285 O  O   . GLY F 1 166 ? 58.214  80.805  29.829  1.00 36.18  ? 166 GLY F O   1 
ATOM   11286 N  N   . ASP F 1 167 ? 59.966  79.383  30.010  1.00 37.65  ? 167 ASP F N   1 
ATOM   11287 C  CA  . ASP F 1 167 ? 59.236  78.213  29.529  1.00 37.12  ? 167 ASP F CA  1 
ATOM   11288 C  C   . ASP F 1 167 ? 59.500  76.975  30.382  1.00 39.08  ? 167 ASP F C   1 
ATOM   11289 O  O   . ASP F 1 167 ? 59.256  75.852  29.916  1.00 34.51  ? 167 ASP F O   1 
ATOM   11290 C  CB  . ASP F 1 167 ? 59.601  77.899  28.062  1.00 32.30  ? 167 ASP F CB  1 
ATOM   11291 C  CG  . ASP F 1 167 ? 61.073  77.494  27.897  1.00 39.17  ? 167 ASP F CG  1 
ATOM   11292 O  OD1 . ASP F 1 167 ? 61.805  77.425  28.918  1.00 37.44  ? 167 ASP F OD1 1 
ATOM   11293 O  OD2 . ASP F 1 167 ? 61.505  77.246  26.747  1.00 38.55  ? 167 ASP F OD2 1 
ATOM   11294 N  N   . ASP F 1 168 ? 60.051  77.146  31.587  1.00 40.64  ? 168 ASP F N   1 
ATOM   11295 C  CA  . ASP F 1 168 ? 60.336  76.075  32.544  1.00 34.89  ? 168 ASP F CA  1 
ATOM   11296 C  C   . ASP F 1 168 ? 61.457  75.145  32.106  1.00 36.68  ? 168 ASP F C   1 
ATOM   11297 O  O   . ASP F 1 168 ? 61.628  74.088  32.716  1.00 33.82  ? 168 ASP F O   1 
ATOM   11298 C  CB  . ASP F 1 168 ? 59.101  75.217  32.834  1.00 36.75  ? 168 ASP F CB  1 
ATOM   11299 C  CG  . ASP F 1 168 ? 58.405  75.621  34.095  1.00 41.39  ? 168 ASP F CG  1 
ATOM   11300 O  OD1 . ASP F 1 168 ? 59.007  75.490  35.179  1.00 43.50  ? 168 ASP F OD1 1 
ATOM   11301 O  OD2 . ASP F 1 168 ? 57.251  76.084  33.999  1.00 52.00  ? 168 ASP F OD2 1 
ATOM   11302 N  N   . THR F 1 169 ? 62.217  75.493  31.064  1.00 33.31  ? 169 THR F N   1 
ATOM   11303 C  CA  . THR F 1 169 ? 63.296  74.613  30.614  1.00 36.51  ? 169 THR F CA  1 
ATOM   11304 C  C   . THR F 1 169 ? 64.467  74.610  31.595  1.00 34.61  ? 169 THR F C   1 
ATOM   11305 O  O   . THR F 1 169 ? 65.012  73.546  31.912  1.00 33.61  ? 169 THR F O   1 
ATOM   11306 C  CB  . THR F 1 169 ? 63.779  75.034  29.225  1.00 32.07  ? 169 THR F CB  1 
ATOM   11307 O  OG1 . THR F 1 169 ? 62.699  74.917  28.297  1.00 38.36  ? 169 THR F OG1 1 
ATOM   11308 C  CG2 . THR F 1 169 ? 64.917  74.141  28.779  1.00 40.40  ? 169 THR F CG2 1 
ATOM   11309 N  N   . ILE F 1 170 ? 64.881  75.795  32.061  1.00 29.05  ? 170 ILE F N   1 
ATOM   11310 C  CA  . ILE F 1 170 ? 66.017  75.981  32.968  1.00 29.98  ? 170 ILE F CA  1 
ATOM   11311 C  C   . ILE F 1 170 ? 65.609  76.963  34.060  1.00 31.77  ? 170 ILE F C   1 
ATOM   11312 O  O   . ILE F 1 170 ? 65.293  78.123  33.758  1.00 27.40  ? 170 ILE F O   1 
ATOM   11313 C  CB  . ILE F 1 170 ? 67.258  76.521  32.239  1.00 29.42  ? 170 ILE F CB  1 
ATOM   11314 C  CG1 . ILE F 1 170 ? 67.593  75.683  31.005  1.00 33.29  ? 170 ILE F CG1 1 
ATOM   11315 C  CG2 . ILE F 1 170 ? 68.442  76.590  33.186  1.00 31.00  ? 170 ILE F CG2 1 
ATOM   11316 C  CD1 . ILE F 1 170 ? 68.653  76.329  30.134  1.00 34.75  ? 170 ILE F CD1 1 
ATOM   11317 N  N   . ARG F 1 171 ? 65.638  76.519  35.326  1.00 27.15  ? 171 ARG F N   1 
ATOM   11318 C  CA  . ARG F 1 171 ? 65.310  77.401  36.447  1.00 27.41  ? 171 ARG F CA  1 
ATOM   11319 C  C   . ARG F 1 171 ? 66.387  77.365  37.526  1.00 27.82  ? 171 ARG F C   1 
ATOM   11320 O  O   . ARG F 1 171 ? 66.836  76.287  37.933  1.00 26.21  ? 171 ARG F O   1 
ATOM   11321 C  CB  . ARG F 1 171 ? 63.956  77.039  37.065  1.00 28.51  ? 171 ARG F CB  1 
ATOM   11322 C  CG  . ARG F 1 171 ? 62.760  77.508  36.246  1.00 27.55  ? 171 ARG F CG  1 
ATOM   11323 C  CD  . ARG F 1 171 ? 61.466  76.897  36.773  1.00 30.88  ? 171 ARG F CD  1 
ATOM   11324 N  NE  . ARG F 1 171 ? 60.773  77.862  37.611  1.00 43.85  ? 171 ARG F NE  1 
ATOM   11325 C  CZ  . ARG F 1 171 ? 59.708  78.569  37.257  1.00 41.38  ? 171 ARG F CZ  1 
ATOM   11326 N  NH1 . ARG F 1 171 ? 59.040  78.312  36.144  1.00 41.98  ? 171 ARG F NH1 1 
ATOM   11327 N  NH2 . ARG F 1 171 ? 59.295  79.553  38.051  1.00 50.03  ? 171 ARG F NH2 1 
ATOM   11328 N  N   . PHE F 1 172 ? 66.790  78.549  37.995  1.00 25.92  ? 172 PHE F N   1 
ATOM   11329 C  CA  . PHE F 1 172 ? 67.689  78.637  39.141  1.00 23.56  ? 172 PHE F CA  1 
ATOM   11330 C  C   . PHE F 1 172 ? 66.980  78.140  40.401  1.00 20.85  ? 172 PHE F C   1 
ATOM   11331 O  O   . PHE F 1 172 ? 65.860  78.556  40.695  1.00 25.33  ? 172 PHE F O   1 
ATOM   11332 C  CB  . PHE F 1 172 ? 68.147  80.082  39.348  1.00 23.12  ? 172 PHE F CB  1 
ATOM   11333 C  CG  . PHE F 1 172 ? 69.274  80.537  38.426  1.00 24.25  ? 172 PHE F CG  1 
ATOM   11334 C  CD1 . PHE F 1 172 ? 69.043  80.798  37.089  1.00 22.57  ? 172 PHE F CD1 1 
ATOM   11335 C  CD2 . PHE F 1 172 ? 70.542  80.763  38.929  1.00 21.44  ? 172 PHE F CD2 1 
ATOM   11336 C  CE1 . PHE F 1 172 ? 70.074  81.235  36.270  1.00 22.06  ? 172 PHE F CE1 1 
ATOM   11337 C  CE2 . PHE F 1 172 ? 71.547  81.208  38.129  1.00 19.76  ? 172 PHE F CE2 1 
ATOM   11338 C  CZ  . PHE F 1 172 ? 71.312  81.446  36.798  1.00 23.07  ? 172 PHE F CZ  1 
ATOM   11339 N  N   . ILE F 1 173 ? 67.634  77.256  41.144  1.00 24.58  ? 173 ILE F N   1 
ATOM   11340 C  CA  . ILE F 1 173 ? 67.159  76.773  42.438  1.00 22.25  ? 173 ILE F CA  1 
ATOM   11341 C  C   . ILE F 1 173 ? 68.203  77.174  43.479  1.00 25.04  ? 173 ILE F C   1 
ATOM   11342 O  O   . ILE F 1 173 ? 69.256  76.527  43.613  1.00 23.50  ? 173 ILE F O   1 
ATOM   11343 C  CB  . ILE F 1 173 ? 66.923  75.261  42.444  1.00 27.60  ? 173 ILE F CB  1 
ATOM   11344 C  CG1 . ILE F 1 173 ? 65.961  74.870  41.306  1.00 24.13  ? 173 ILE F CG1 1 
ATOM   11345 C  CG2 . ILE F 1 173 ? 66.461  74.809  43.831  1.00 19.17  ? 173 ILE F CG2 1 
ATOM   11346 C  CD1 . ILE F 1 173 ? 64.530  75.348  41.508  1.00 26.33  ? 173 ILE F CD1 1 
ATOM   11347 N  N   . PHE F 1 174 ? 67.913  78.239  44.226  1.00 21.77  ? 174 PHE F N   1 
ATOM   11348 C  CA  . PHE F 1 174 ? 68.888  78.775  45.174  1.00 24.97  ? 174 PHE F CA  1 
ATOM   11349 C  C   . PHE F 1 174 ? 69.210  77.746  46.256  1.00 20.73  ? 174 PHE F C   1 
ATOM   11350 O  O   . PHE F 1 174 ? 68.315  77.188  46.896  1.00 21.19  ? 174 PHE F O   1 
ATOM   11351 C  CB  . PHE F 1 174 ? 68.368  80.073  45.810  1.00 24.63  ? 174 PHE F CB  1 
ATOM   11352 C  CG  . PHE F 1 174 ? 68.329  81.267  44.866  1.00 23.71  ? 174 PHE F CG  1 
ATOM   11353 C  CD1 . PHE F 1 174 ? 68.709  81.148  43.539  1.00 25.51  ? 174 PHE F CD1 1 
ATOM   11354 C  CD2 . PHE F 1 174 ? 67.881  82.513  45.325  1.00 25.59  ? 174 PHE F CD2 1 
ATOM   11355 C  CE1 . PHE F 1 174 ? 68.657  82.250  42.677  1.00 24.33  ? 174 PHE F CE1 1 
ATOM   11356 C  CE2 . PHE F 1 174 ? 67.820  83.617  44.482  1.00 25.13  ? 174 PHE F CE2 1 
ATOM   11357 C  CZ  . PHE F 1 174 ? 68.210  83.492  43.154  1.00 27.13  ? 174 PHE F CZ  1 
ATOM   11358 N  N   . THR F 1 175 ? 70.499  77.497  46.459  1.00 20.97  ? 175 THR F N   1 
ATOM   11359 C  CA  . THR F 1 175 ? 70.975  76.525  47.447  1.00 21.15  ? 175 THR F CA  1 
ATOM   11360 C  C   . THR F 1 175 ? 72.194  77.104  48.166  1.00 24.03  ? 175 THR F C   1 
ATOM   11361 O  O   . THR F 1 175 ? 73.326  76.664  47.957  1.00 23.47  ? 175 THR F O   1 
ATOM   11362 C  CB  . THR F 1 175 ? 71.296  75.179  46.779  1.00 23.73  ? 175 THR F CB  1 
ATOM   11363 O  OG1 . THR F 1 175 ? 72.034  75.384  45.554  1.00 21.68  ? 175 THR F OG1 1 
ATOM   11364 C  CG2 . THR F 1 175 ? 69.996  74.428  46.449  1.00 15.12  ? 175 THR F CG2 1 
ATOM   11365 N  N   . PRO F 1 176 ? 71.996  78.115  49.019  1.00 23.79  ? 176 PRO F N   1 
ATOM   11366 C  CA  . PRO F 1 176 ? 73.150  78.739  49.697  1.00 23.40  ? 176 PRO F CA  1 
ATOM   11367 C  C   . PRO F 1 176 ? 73.816  77.783  50.673  1.00 26.02  ? 176 PRO F C   1 
ATOM   11368 O  O   . PRO F 1 176 ? 73.188  76.865  51.212  1.00 23.28  ? 176 PRO F O   1 
ATOM   11369 C  CB  . PRO F 1 176 ? 72.536  79.929  50.443  1.00 23.33  ? 176 PRO F CB  1 
ATOM   11370 C  CG  . PRO F 1 176 ? 71.062  79.497  50.675  1.00 24.11  ? 176 PRO F CG  1 
ATOM   11371 C  CD  . PRO F 1 176 ? 70.704  78.664  49.467  1.00 25.49  ? 176 PRO F CD  1 
ATOM   11372 N  N   . GLY F 1 177 ? 75.106  78.010  50.902  1.00 24.59  ? 177 GLY F N   1 
ATOM   11373 C  CA  . GLY F 1 177 ? 75.813  77.194  51.867  1.00 21.19  ? 177 GLY F CA  1 
ATOM   11374 C  C   . GLY F 1 177 ? 77.203  76.790  51.419  1.00 23.85  ? 177 GLY F C   1 
ATOM   11375 O  O   . GLY F 1 177 ? 78.204  77.169  52.043  1.00 26.14  ? 177 GLY F O   1 
ATOM   11376 N  N   . HIS F 1 178 ? 77.292  75.995  50.357  1.00 26.22  ? 178 HIS F N   1 
ATOM   11377 C  CA  . HIS F 1 178 ? 78.615  75.678  49.842  1.00 28.46  ? 178 HIS F CA  1 
ATOM   11378 C  C   . HIS F 1 178 ? 79.355  76.958  49.490  1.00 24.30  ? 178 HIS F C   1 
ATOM   11379 O  O   . HIS F 1 178 ? 80.515  77.138  49.862  1.00 27.89  ? 178 HIS F O   1 
ATOM   11380 C  CB  . HIS F 1 178 ? 78.531  74.759  48.635  1.00 25.43  ? 178 HIS F CB  1 
ATOM   11381 C  CG  . HIS F 1 178 ? 79.829  74.660  47.899  1.00 29.37  ? 178 HIS F CG  1 
ATOM   11382 N  ND1 . HIS F 1 178 ? 80.939  74.030  48.428  1.00 30.17  ? 178 HIS F ND1 1 
ATOM   11383 C  CD2 . HIS F 1 178 ? 80.213  75.162  46.708  1.00 26.64  ? 178 HIS F CD2 1 
ATOM   11384 C  CE1 . HIS F 1 178 ? 81.942  74.131  47.580  1.00 34.31  ? 178 HIS F CE1 1 
ATOM   11385 N  NE2 . HIS F 1 178 ? 81.524  74.798  46.521  1.00 35.37  ? 178 HIS F NE2 1 
ATOM   11386 N  N   . ALA F 1 179 ? 78.679  77.869  48.805  1.00 23.01  ? 179 ALA F N   1 
ATOM   11387 C  CA  . ALA F 1 179 ? 79.088  79.250  48.604  1.00 21.32  ? 179 ALA F CA  1 
ATOM   11388 C  C   . ALA F 1 179 ? 77.916  80.141  48.983  1.00 21.81  ? 179 ALA F C   1 
ATOM   11389 O  O   . ALA F 1 179 ? 76.763  79.693  48.974  1.00 25.01  ? 179 ALA F O   1 
ATOM   11390 C  CB  . ALA F 1 179 ? 79.501  79.509  47.146  1.00 24.58  ? 179 ALA F CB  1 
ATOM   11391 N  N   . PRO F 1 180 ? 78.164  81.407  49.323  1.00 22.55  ? 180 PRO F N   1 
ATOM   11392 C  CA  . PRO F 1 180 ? 77.037  82.269  49.729  1.00 24.07  ? 180 PRO F CA  1 
ATOM   11393 C  C   . PRO F 1 180 ? 75.969  82.392  48.659  1.00 25.20  ? 180 PRO F C   1 
ATOM   11394 O  O   . PRO F 1 180 ? 74.770  82.357  48.972  1.00 17.31  ? 180 PRO F O   1 
ATOM   11395 C  CB  . PRO F 1 180 ? 77.701  83.625  50.010  1.00 21.09  ? 180 PRO F CB  1 
ATOM   11396 C  CG  . PRO F 1 180 ? 79.136  83.338  50.207  1.00 21.78  ? 180 PRO F CG  1 
ATOM   11397 C  CD  . PRO F 1 180 ? 79.464  82.093  49.425  1.00 21.85  ? 180 PRO F CD  1 
ATOM   11398 N  N   . GLY F 1 181 ? 76.375  82.528  47.396  1.00 19.27  ? 181 GLY F N   1 
ATOM   11399 C  CA  . GLY F 1 181 ? 75.423  82.714  46.321  1.00 20.86  ? 181 GLY F CA  1 
ATOM   11400 C  C   . GLY F 1 181 ? 75.181  81.488  45.459  1.00 23.32  ? 181 GLY F C   1 
ATOM   11401 O  O   . GLY F 1 181 ? 74.769  81.615  44.292  1.00 23.91  ? 181 GLY F O   1 
ATOM   11402 N  N   . HIS F 1 182 ? 75.413  80.303  46.019  1.00 20.50  ? 182 HIS F N   1 
ATOM   11403 C  CA  . HIS F 1 182 ? 75.345  79.079  45.228  1.00 24.47  ? 182 HIS F CA  1 
ATOM   11404 C  C   . HIS F 1 182 ? 73.918  78.786  44.763  1.00 24.13  ? 182 HIS F C   1 
ATOM   11405 O  O   . HIS F 1 182 ? 72.948  78.870  45.532  1.00 22.76  ? 182 HIS F O   1 
ATOM   11406 C  CB  . HIS F 1 182 ? 75.892  77.874  46.021  1.00 22.17  ? 182 HIS F CB  1 
ATOM   11407 C  CG  . HIS F 1 182 ? 75.897  76.602  45.232  1.00 27.77  ? 182 HIS F CG  1 
ATOM   11408 N  ND1 . HIS F 1 182 ? 74.801  75.762  45.162  1.00 26.64  ? 182 HIS F ND1 1 
ATOM   11409 C  CD2 . HIS F 1 182 ? 76.847  76.053  44.428  1.00 26.75  ? 182 HIS F CD2 1 
ATOM   11410 C  CE1 . HIS F 1 182 ? 75.085  74.742  44.364  1.00 26.30  ? 182 HIS F CE1 1 
ATOM   11411 N  NE2 . HIS F 1 182 ? 76.321  74.892  43.914  1.00 23.77  ? 182 HIS F NE2 1 
ATOM   11412 N  N   . SER F 1 183 ? 73.797  78.402  43.504  1.00 21.91  ? 183 SER F N   1 
ATOM   11413 C  CA  . SER F 1 183 ? 72.517  77.984  42.959  1.00 21.10  ? 183 SER F CA  1 
ATOM   11414 C  C   . SER F 1 183 ? 72.674  76.652  42.241  1.00 25.60  ? 183 SER F C   1 
ATOM   11415 O  O   . SER F 1 183 ? 73.662  76.422  41.538  1.00 24.35  ? 183 SER F O   1 
ATOM   11416 C  CB  . SER F 1 183 ? 71.953  79.037  42.006  1.00 22.05  ? 183 SER F CB  1 
ATOM   11417 O  OG  . SER F 1 183 ? 70.602  78.744  41.694  1.00 30.76  ? 183 SER F OG  1 
ATOM   11418 N  N   . SER F 1 184 ? 71.709  75.772  42.451  1.00 23.40  ? 184 SER F N   1 
ATOM   11419 C  CA  . SER F 1 184 ? 71.522  74.581  41.645  1.00 20.82  ? 184 SER F CA  1 
ATOM   11420 C  C   . SER F 1 184 ? 70.573  74.910  40.489  1.00 26.33  ? 184 SER F C   1 
ATOM   11421 O  O   . SER F 1 184 ? 70.123  76.050  40.330  1.00 22.49  ? 184 SER F O   1 
ATOM   11422 C  CB  . SER F 1 184 ? 70.958  73.451  42.502  1.00 26.34  ? 184 SER F CB  1 
ATOM   11423 O  OG  . SER F 1 184 ? 71.681  73.316  43.708  1.00 24.54  ? 184 SER F OG  1 
ATOM   11424 N  N   . PHE F 1 185 ? 70.233  73.900  39.679  1.00 25.69  ? 185 PHE F N   1 
ATOM   11425 C  CA  . PHE F 1 185 ? 69.392  74.132  38.507  1.00 23.52  ? 185 PHE F CA  1 
ATOM   11426 C  C   . PHE F 1 185 ? 68.371  73.011  38.348  1.00 25.54  ? 185 PHE F C   1 
ATOM   11427 O  O   . PHE F 1 185 ? 68.711  71.831  38.477  1.00 29.52  ? 185 PHE F O   1 
ATOM   11428 C  CB  . PHE F 1 185 ? 70.252  74.265  37.250  1.00 27.14  ? 185 PHE F CB  1 
ATOM   11429 C  CG  . PHE F 1 185 ? 71.139  75.470  37.261  1.00 24.72  ? 185 PHE F CG  1 
ATOM   11430 C  CD1 . PHE F 1 185 ? 70.656  76.700  36.870  1.00 22.37  ? 185 PHE F CD1 1 
ATOM   11431 C  CD2 . PHE F 1 185 ? 72.456  75.375  37.694  1.00 27.43  ? 185 PHE F CD2 1 
ATOM   11432 C  CE1 . PHE F 1 185 ? 71.465  77.824  36.895  1.00 23.09  ? 185 PHE F CE1 1 
ATOM   11433 C  CE2 . PHE F 1 185 ? 73.276  76.495  37.721  1.00 26.72  ? 185 PHE F CE2 1 
ATOM   11434 C  CZ  . PHE F 1 185 ? 72.778  77.720  37.331  1.00 23.81  ? 185 PHE F CZ  1 
ATOM   11435 N  N   . LEU F 1 186 ? 67.119  73.375  38.097  1.00 24.30  ? 186 LEU F N   1 
ATOM   11436 C  CA  . LEU F 1 186 ? 66.098  72.409  37.716  1.00 26.18  ? 186 LEU F CA  1 
ATOM   11437 C  C   . LEU F 1 186 ? 65.831  72.556  36.225  1.00 29.54  ? 186 LEU F C   1 
ATOM   11438 O  O   . LEU F 1 186 ? 65.462  73.636  35.759  1.00 32.18  ? 186 LEU F O   1 
ATOM   11439 C  CB  . LEU F 1 186 ? 64.802  72.585  38.502  1.00 25.51  ? 186 LEU F CB  1 
ATOM   11440 C  CG  . LEU F 1 186 ? 63.714  71.579  38.079  1.00 30.11  ? 186 LEU F CG  1 
ATOM   11441 C  CD1 . LEU F 1 186 ? 64.036  70.147  38.543  1.00 28.07  ? 186 LEU F CD1 1 
ATOM   11442 C  CD2 . LEU F 1 186 ? 62.344  71.992  38.583  1.00 26.07  ? 186 LEU F CD2 1 
ATOM   11443 N  N   . LEU F 1 187 ? 66.029  71.479  35.479  1.00 31.35  ? 187 LEU F N   1 
ATOM   11444 C  CA  . LEU F 1 187 ? 65.758  71.478  34.052  1.00 32.11  ? 187 LEU F CA  1 
ATOM   11445 C  C   . LEU F 1 187 ? 64.536  70.614  33.793  1.00 30.73  ? 187 LEU F C   1 
ATOM   11446 O  O   . LEU F 1 187 ? 64.246  69.687  34.554  1.00 31.18  ? 187 LEU F O   1 
ATOM   11447 C  CB  . LEU F 1 187 ? 66.973  70.969  33.258  1.00 28.07  ? 187 LEU F CB  1 
ATOM   11448 C  CG  . LEU F 1 187 ? 68.035  72.021  32.887  1.00 35.44  ? 187 LEU F CG  1 
ATOM   11449 C  CD1 . LEU F 1 187 ? 68.421  72.913  34.065  1.00 32.17  ? 187 LEU F CD1 1 
ATOM   11450 C  CD2 . LEU F 1 187 ? 69.291  71.392  32.277  1.00 31.66  ? 187 LEU F CD2 1 
ATOM   11451 N  N   . ARG F 1 188 ? 63.787  70.963  32.749  1.00 36.12  ? 188 ARG F N   1 
ATOM   11452 C  CA  . ARG F 1 188 ? 62.725  70.110  32.224  1.00 35.12  ? 188 ARG F CA  1 
ATOM   11453 C  C   . ARG F 1 188 ? 62.970  69.889  30.739  1.00 38.39  ? 188 ARG F C   1 
ATOM   11454 O  O   . ARG F 1 188 ? 63.000  70.849  29.961  1.00 37.53  ? 188 ARG F O   1 
ATOM   11455 C  CB  . ARG F 1 188 ? 61.341  70.712  32.461  1.00 33.59  ? 188 ARG F CB  1 
ATOM   11456 C  CG  . ARG F 1 188 ? 60.935  70.657  33.905  1.00 33.81  ? 188 ARG F CG  1 
ATOM   11457 C  CD  . ARG F 1 188 ? 59.467  70.832  34.072  1.00 34.79  ? 188 ARG F CD  1 
ATOM   11458 N  NE  . ARG F 1 188 ? 59.144  70.974  35.483  1.00 39.98  ? 188 ARG F NE  1 
ATOM   11459 C  CZ  . ARG F 1 188 ? 58.652  70.000  36.236  1.00 36.65  ? 188 ARG F CZ  1 
ATOM   11460 N  NH1 . ARG F 1 188 ? 58.400  68.803  35.740  1.00 31.19  ? 188 ARG F NH1 1 
ATOM   11461 N  NH2 . ARG F 1 188 ? 58.442  70.225  37.528  1.00 33.32  ? 188 ARG F NH2 1 
ATOM   11462 N  N   . LEU F 1 189 ? 63.163  68.621  30.353  1.00 38.69  ? 189 LEU F N   1 
ATOM   11463 C  CA  . LEU F 1 189 ? 63.407  68.257  28.972  1.00 40.59  ? 189 LEU F CA  1 
ATOM   11464 C  C   . LEU F 1 189 ? 62.236  67.452  28.408  1.00 42.04  ? 189 LEU F C   1 
ATOM   11465 O  O   . LEU F 1 189 ? 61.596  66.684  29.143  1.00 42.65  ? 189 LEU F O   1 
ATOM   11466 C  CB  . LEU F 1 189 ? 64.702  67.450  28.864  1.00 39.12  ? 189 LEU F CB  1 
ATOM   11467 C  CG  . LEU F 1 189 ? 65.919  68.268  29.310  1.00 39.84  ? 189 LEU F CG  1 
ATOM   11468 C  CD1 . LEU F 1 189 ? 67.060  67.348  29.688  1.00 44.76  ? 189 LEU F CD1 1 
ATOM   11469 C  CD2 . LEU F 1 189 ? 66.369  69.242  28.237  1.00 36.74  ? 189 LEU F CD2 1 
ATOM   11470 N  N   . PRO F 1 190 ? 61.913  67.646  27.121  1.00 41.51  ? 190 PRO F N   1 
ATOM   11471 C  CA  . PRO F 1 190 ? 60.714  66.999  26.548  1.00 40.51  ? 190 PRO F CA  1 
ATOM   11472 C  C   . PRO F 1 190 ? 60.603  65.513  26.853  1.00 42.96  ? 190 PRO F C   1 
ATOM   11473 O  O   . PRO F 1 190 ? 59.570  65.058  27.371  1.00 41.06  ? 190 PRO F O   1 
ATOM   11474 C  CB  . PRO F 1 190 ? 60.881  67.255  25.044  1.00 42.54  ? 190 PRO F CB  1 
ATOM   11475 C  CG  . PRO F 1 190 ? 61.678  68.527  24.956  1.00 44.78  ? 190 PRO F CG  1 
ATOM   11476 C  CD  . PRO F 1 190 ? 62.569  68.567  26.173  1.00 42.17  ? 190 PRO F CD  1 
ATOM   11477 N  N   . GLU F 1 191 ? 61.658  64.746  26.571  1.00 40.38  ? 191 GLU F N   1 
ATOM   11478 C  CA  . GLU F 1 191 ? 61.615  63.302  26.755  1.00 41.81  ? 191 GLU F CA  1 
ATOM   11479 C  C   . GLU F 1 191 ? 62.062  62.878  28.150  1.00 40.77  ? 191 GLU F C   1 
ATOM   11480 O  O   . GLU F 1 191 ? 61.398  62.063  28.799  1.00 41.58  ? 191 GLU F O   1 
ATOM   11481 C  CB  . GLU F 1 191 ? 62.488  62.622  25.699  1.00 42.83  ? 191 GLU F CB  1 
ATOM   11482 C  CG  . GLU F 1 191 ? 61.958  62.740  24.287  1.00 48.36  ? 191 GLU F CG  1 
ATOM   11483 C  CD  . GLU F 1 191 ? 62.816  61.973  23.289  1.00 52.34  ? 191 GLU F CD  1 
ATOM   11484 O  OE1 . GLU F 1 191 ? 63.091  60.779  23.544  1.00 53.88  ? 191 GLU F OE1 1 
ATOM   11485 O  OE2 . GLU F 1 191 ? 63.208  62.560  22.254  1.00 44.91  ? 191 GLU F OE2 1 
ATOM   11486 N  N   . THR F 1 192 ? 63.195  63.407  28.611  1.00 42.71  ? 192 THR F N   1 
ATOM   11487 C  CA  . THR F 1 192 ? 63.724  63.023  29.917  1.00 40.58  ? 192 THR F CA  1 
ATOM   11488 C  C   . THR F 1 192 ? 62.804  63.444  31.062  1.00 38.31  ? 192 THR F C   1 
ATOM   11489 O  O   . THR F 1 192 ? 62.682  62.718  32.055  1.00 38.66  ? 192 THR F O   1 
ATOM   11490 C  CB  . THR F 1 192 ? 65.118  63.629  30.079  1.00 45.51  ? 192 THR F CB  1 
ATOM   11491 O  OG1 . THR F 1 192 ? 65.882  63.362  28.892  1.00 42.01  ? 192 THR F OG1 1 
ATOM   11492 C  CG2 . THR F 1 192 ? 65.838  63.074  31.300  1.00 38.56  ? 192 THR F CG2 1 
ATOM   11493 N  N   . GLY F 1 193 ? 62.122  64.583  30.933  1.00 39.47  ? 193 GLY F N   1 
ATOM   11494 C  CA  . GLY F 1 193 ? 61.400  65.164  32.045  1.00 37.65  ? 193 GLY F CA  1 
ATOM   11495 C  C   . GLY F 1 193 ? 62.299  66.054  32.890  1.00 37.59  ? 193 GLY F C   1 
ATOM   11496 O  O   . GLY F 1 193 ? 63.234  66.691  32.382  1.00 35.34  ? 193 GLY F O   1 
ATOM   11497 N  N   . PRO F 1 194 ? 62.035  66.107  34.199  1.00 35.70  ? 194 PRO F N   1 
ATOM   11498 C  CA  . PRO F 1 194 ? 62.838  66.956  35.099  1.00 33.73  ? 194 PRO F CA  1 
ATOM   11499 C  C   . PRO F 1 194 ? 64.219  66.397  35.402  1.00 31.58  ? 194 PRO F C   1 
ATOM   11500 O  O   . PRO F 1 194 ? 64.380  65.230  35.766  1.00 32.27  ? 194 PRO F O   1 
ATOM   11501 C  CB  . PRO F 1 194 ? 62.008  67.015  36.389  1.00 30.90  ? 194 PRO F CB  1 
ATOM   11502 C  CG  . PRO F 1 194 ? 60.977  65.921  36.293  1.00 33.43  ? 194 PRO F CG  1 
ATOM   11503 C  CD  . PRO F 1 194 ? 60.860  65.501  34.857  1.00 37.11  ? 194 PRO F CD  1 
ATOM   11504 N  N   . VAL F 1 195 ? 65.211  67.280  35.332  1.00 31.26  ? 195 VAL F N   1 
ATOM   11505 C  CA  . VAL F 1 195 ? 66.600  66.971  35.675  1.00 32.51  ? 195 VAL F CA  1 
ATOM   11506 C  C   . VAL F 1 195 ? 67.083  68.013  36.680  1.00 30.97  ? 195 VAL F C   1 
ATOM   11507 O  O   . VAL F 1 195 ? 67.067  69.215  36.383  1.00 27.68  ? 195 VAL F O   1 
ATOM   11508 C  CB  . VAL F 1 195 ? 67.515  66.967  34.433  1.00 33.96  ? 195 VAL F CB  1 
ATOM   11509 C  CG1 . VAL F 1 195 ? 68.950  66.572  34.810  1.00 30.87  ? 195 VAL F CG1 1 
ATOM   11510 C  CG2 . VAL F 1 195 ? 66.937  66.051  33.356  1.00 32.09  ? 195 VAL F CG2 1 
ATOM   11511 N  N   . LEU F 1 196 ? 67.548  67.553  37.844  1.00 31.53  ? 196 LEU F N   1 
ATOM   11512 C  CA  . LEU F 1 196 ? 67.990  68.424  38.939  1.00 29.02  ? 196 LEU F CA  1 
ATOM   11513 C  C   . LEU F 1 196 ? 69.514  68.421  39.021  1.00 27.59  ? 196 LEU F C   1 
ATOM   11514 O  O   . LEU F 1 196 ? 70.120  67.467  39.520  1.00 30.14  ? 196 LEU F O   1 
ATOM   11515 C  CB  . LEU F 1 196 ? 67.380  67.989  40.266  1.00 30.43  ? 196 LEU F CB  1 
ATOM   11516 C  CG  . LEU F 1 196 ? 67.851  68.774  41.499  1.00 28.95  ? 196 LEU F CG  1 
ATOM   11517 C  CD1 . LEU F 1 196 ? 67.609  70.249  41.280  1.00 28.02  ? 196 LEU F CD1 1 
ATOM   11518 C  CD2 . LEU F 1 196 ? 67.131  68.299  42.743  1.00 24.81  ? 196 LEU F CD2 1 
ATOM   11519 N  N   . LEU F 1 197 ? 70.133  69.498  38.539  1.00 27.57  ? 197 LEU F N   1 
ATOM   11520 C  CA  . LEU F 1 197 ? 71.577  69.675  38.657  1.00 26.35  ? 197 LEU F CA  1 
ATOM   11521 C  C   . LEU F 1 197 ? 71.877  70.253  40.040  1.00 28.12  ? 197 LEU F C   1 
ATOM   11522 O  O   . LEU F 1 197 ? 71.690  71.450  40.282  1.00 25.92  ? 197 LEU F O   1 
ATOM   11523 C  CB  . LEU F 1 197 ? 72.098  70.580  37.544  1.00 28.52  ? 197 LEU F CB  1 
ATOM   11524 C  CG  . LEU F 1 197 ? 71.785  70.157  36.099  1.00 30.24  ? 197 LEU F CG  1 
ATOM   11525 C  CD1 . LEU F 1 197 ? 72.301  71.186  35.082  1.00 25.41  ? 197 LEU F CD1 1 
ATOM   11526 C  CD2 . LEU F 1 197 ? 72.361  68.777  35.812  1.00 27.75  ? 197 LEU F CD2 1 
ATOM   11527 N  N   . ALA F 1 198 ? 72.334  69.407  40.966  1.00 25.46  ? 198 ALA F N   1 
ATOM   11528 C  CA  . ALA F 1 198 ? 72.633  69.919  42.300  1.00 29.25  ? 198 ALA F CA  1 
ATOM   11529 C  C   . ALA F 1 198 ? 73.898  70.769  42.345  1.00 29.94  ? 198 ALA F C   1 
ATOM   11530 O  O   . ALA F 1 198 ? 74.041  71.573  43.269  1.00 29.03  ? 198 ALA F O   1 
ATOM   11531 C  CB  . ALA F 1 198 ? 72.766  68.781  43.304  1.00 26.43  ? 198 ALA F CB  1 
ATOM   11532 N  N   . VAL F 1 199 ? 74.798  70.628  41.366  1.00 29.77  ? 199 VAL F N   1 
ATOM   11533 C  CA  . VAL F 1 199 ? 76.144  71.215  41.391  1.00 29.49  ? 199 VAL F CA  1 
ATOM   11534 C  C   . VAL F 1 199 ? 76.759  70.999  42.774  1.00 31.86  ? 199 VAL F C   1 
ATOM   11535 O  O   . VAL F 1 199 ? 76.629  69.916  43.345  1.00 28.46  ? 199 VAL F O   1 
ATOM   11536 C  CB  . VAL F 1 199 ? 76.127  72.698  40.984  1.00 28.38  ? 199 VAL F CB  1 
ATOM   11537 C  CG1 . VAL F 1 199 ? 77.504  73.123  40.517  1.00 32.42  ? 199 VAL F CG1 1 
ATOM   11538 C  CG2 . VAL F 1 199 ? 75.135  72.919  39.842  1.00 29.39  ? 199 VAL F CG2 1 
ATOM   11539 N  N   . ASP F 1 200 ? 77.411  72.012  43.347  1.00 30.58  ? 200 ASP F N   1 
ATOM   11540 C  CA  . ASP F 1 200 ? 78.111  71.780  44.604  1.00 29.84  ? 200 ASP F CA  1 
ATOM   11541 C  C   . ASP F 1 200 ? 77.220  71.860  45.839  1.00 30.93  ? 200 ASP F C   1 
ATOM   11542 O  O   . ASP F 1 200 ? 77.753  71.823  46.948  1.00 28.29  ? 200 ASP F O   1 
ATOM   11543 C  CB  . ASP F 1 200 ? 79.264  72.756  44.775  1.00 33.15  ? 200 ASP F CB  1 
ATOM   11544 C  CG  . ASP F 1 200 ? 80.423  72.454  43.855  1.00 36.21  ? 200 ASP F CG  1 
ATOM   11545 O  OD1 . ASP F 1 200 ? 80.257  71.645  42.926  1.00 36.61  ? 200 ASP F OD1 1 
ATOM   11546 O  OD2 . ASP F 1 200 ? 81.504  73.018  44.083  1.00 38.53  ? 200 ASP F OD2 1 
ATOM   11547 N  N   . ALA F 1 201 ? 75.901  71.970  45.700  1.00 28.10  ? 201 ALA F N   1 
ATOM   11548 C  CA  . ALA F 1 201 ? 75.060  71.835  46.884  1.00 26.89  ? 201 ALA F CA  1 
ATOM   11549 C  C   . ALA F 1 201 ? 75.050  70.406  47.421  1.00 28.73  ? 201 ALA F C   1 
ATOM   11550 O  O   . ALA F 1 201 ? 74.728  70.189  48.599  1.00 27.77  ? 201 ALA F O   1 
ATOM   11551 C  CB  . ALA F 1 201 ? 73.642  72.300  46.573  1.00 23.06  ? 201 ALA F CB  1 
ATOM   11552 N  N   . ALA F 1 202 ? 75.406  69.426  46.591  1.00 27.53  ? 202 ALA F N   1 
ATOM   11553 C  CA  . ALA F 1 202 ? 75.494  68.033  47.049  1.00 27.54  ? 202 ALA F CA  1 
ATOM   11554 C  C   . ALA F 1 202 ? 76.563  67.344  46.190  1.00 33.90  ? 202 ALA F C   1 
ATOM   11555 O  O   . ALA F 1 202 ? 76.276  66.843  45.101  1.00 31.49  ? 202 ALA F O   1 
ATOM   11556 C  CB  . ALA F 1 202 ? 74.147  67.329  46.970  1.00 27.84  ? 202 ALA F CB  1 
ATOM   11557 N  N   . TYR F 1 203 ? 77.804  67.376  46.693  1.00 30.72  ? 203 TYR F N   1 
ATOM   11558 C  CA  . TYR F 1 203 ? 78.967  66.826  46.004  1.00 36.60  ? 203 TYR F CA  1 
ATOM   11559 C  C   . TYR F 1 203 ? 78.728  65.385  45.540  1.00 39.25  ? 203 TYR F C   1 
ATOM   11560 O  O   . TYR F 1 203 ? 78.962  65.039  44.373  1.00 34.37  ? 203 TYR F O   1 
ATOM   11561 C  CB  . TYR F 1 203 ? 80.158  66.872  46.960  1.00 36.43  ? 203 TYR F CB  1 
ATOM   11562 C  CG  . TYR F 1 203 ? 80.973  68.154  47.016  1.00 40.43  ? 203 TYR F CG  1 
ATOM   11563 C  CD1 . TYR F 1 203 ? 81.034  69.034  45.939  1.00 39.95  ? 203 TYR F CD1 1 
ATOM   11564 C  CD2 . TYR F 1 203 ? 81.708  68.465  48.158  1.00 42.99  ? 203 TYR F CD2 1 
ATOM   11565 C  CE1 . TYR F 1 203 ? 81.810  70.190  46.004  1.00 43.05  ? 203 TYR F CE1 1 
ATOM   11566 C  CE2 . TYR F 1 203 ? 82.474  69.614  48.235  1.00 42.41  ? 203 TYR F CE2 1 
ATOM   11567 C  CZ  . TYR F 1 203 ? 82.524  70.472  47.163  1.00 44.35  ? 203 TYR F CZ  1 
ATOM   11568 O  OH  . TYR F 1 203 ? 83.306  71.607  47.249  1.00 44.62  ? 203 TYR F OH  1 
ATOM   11569 N  N   . THR F 1 204 ? 78.266  64.533  46.458  1.00 32.56  ? 204 THR F N   1 
ATOM   11570 C  CA  . THR F 1 204 ? 78.158  63.095  46.271  1.00 34.44  ? 204 THR F CA  1 
ATOM   11571 C  C   . THR F 1 204 ? 76.842  62.621  46.873  1.00 36.79  ? 204 THR F C   1 
ATOM   11572 O  O   . THR F 1 204 ? 76.102  63.397  47.483  1.00 37.91  ? 204 THR F O   1 
ATOM   11573 C  CB  . THR F 1 204 ? 79.320  62.352  46.944  1.00 34.84  ? 204 THR F CB  1 
ATOM   11574 O  OG1 . THR F 1 204 ? 79.105  62.340  48.357  1.00 35.11  ? 204 THR F OG1 1 
ATOM   11575 C  CG2 . THR F 1 204 ? 80.666  63.027  46.662  1.00 38.75  ? 204 THR F CG2 1 
ATOM   11576 N  N   . THR F 1 205 ? 76.575  61.318  46.747  1.00 36.98  ? 205 THR F N   1 
ATOM   11577 C  CA  . THR F 1 205 ? 75.374  60.744  47.338  1.00 37.89  ? 205 THR F CA  1 
ATOM   11578 C  C   . THR F 1 205 ? 75.471  60.649  48.859  1.00 38.13  ? 205 THR F C   1 
ATOM   11579 O  O   . THR F 1 205 ? 74.434  60.595  49.532  1.00 35.17  ? 205 THR F O   1 
ATOM   11580 C  CB  . THR F 1 205 ? 75.083  59.351  46.743  1.00 45.29  ? 205 THR F CB  1 
ATOM   11581 O  OG1 . THR F 1 205 ? 76.023  58.394  47.248  1.00 41.73  ? 205 THR F OG1 1 
ATOM   11582 C  CG2 . THR F 1 205 ? 75.180  59.373  45.218  1.00 41.82  ? 205 THR F CG2 1 
ATOM   11583 N  N   . ASP F 1 206 ? 76.685  60.613  49.418  1.00 35.80  ? 206 ASP F N   1 
ATOM   11584 C  CA  . ASP F 1 206 ? 76.812  60.716  50.870  1.00 39.86  ? 206 ASP F CA  1 
ATOM   11585 C  C   . ASP F 1 206 ? 76.284  62.062  51.366  1.00 36.26  ? 206 ASP F C   1 
ATOM   11586 O  O   . ASP F 1 206 ? 75.604  62.136  52.401  1.00 35.45  ? 206 ASP F O   1 
ATOM   11587 C  CB  . ASP F 1 206 ? 78.272  60.525  51.304  1.00 41.70  ? 206 ASP F CB  1 
ATOM   11588 C  CG  . ASP F 1 206 ? 78.692  59.048  51.381  1.00 52.40  ? 206 ASP F CG  1 
ATOM   11589 O  OD1 . ASP F 1 206 ? 77.797  58.167  51.395  1.00 48.37  ? 206 ASP F OD1 1 
ATOM   11590 O  OD2 . ASP F 1 206 ? 79.921  58.777  51.469  1.00 49.04  ? 206 ASP F OD2 1 
ATOM   11591 N  N   . HIS F 1 207 ? 76.602  63.140  50.647  1.00 34.95  ? 207 HIS F N   1 
ATOM   11592 C  CA  . HIS F 1 207 ? 76.061  64.447  50.999  1.00 37.22  ? 207 HIS F CA  1 
ATOM   11593 C  C   . HIS F 1 207 ? 74.541  64.445  50.899  1.00 32.96  ? 207 HIS F C   1 
ATOM   11594 O  O   . HIS F 1 207 ? 73.848  64.866  51.828  1.00 32.50  ? 207 HIS F O   1 
ATOM   11595 C  CB  . HIS F 1 207 ? 76.679  65.517  50.099  1.00 36.19  ? 207 HIS F CB  1 
ATOM   11596 C  CG  . HIS F 1 207 ? 78.138  65.717  50.344  1.00 40.60  ? 207 HIS F CG  1 
ATOM   11597 N  ND1 . HIS F 1 207 ? 79.109  65.098  49.585  1.00 45.67  ? 207 HIS F ND1 1 
ATOM   11598 C  CD2 . HIS F 1 207 ? 78.797  66.445  51.278  1.00 39.08  ? 207 HIS F CD2 1 
ATOM   11599 C  CE1 . HIS F 1 207 ? 80.303  65.446  50.033  1.00 43.46  ? 207 HIS F CE1 1 
ATOM   11600 N  NE2 . HIS F 1 207 ? 80.142  66.259  51.061  1.00 42.83  ? 207 HIS F NE2 1 
ATOM   11601 N  N   . TRP F 1 208 ? 74.007  63.950  49.779  1.00 32.67  ? 208 TRP F N   1 
ATOM   11602 C  CA  . TRP F 1 208 ? 72.558  63.851  49.618  1.00 33.95  ? 208 TRP F CA  1 
ATOM   11603 C  C   . TRP F 1 208 ? 71.919  63.093  50.768  1.00 29.95  ? 208 TRP F C   1 
ATOM   11604 O  O   . TRP F 1 208 ? 70.886  63.511  51.296  1.00 31.83  ? 208 TRP F O   1 
ATOM   11605 C  CB  . TRP F 1 208 ? 72.225  63.166  48.293  1.00 36.94  ? 208 TRP F CB  1 
ATOM   11606 C  CG  . TRP F 1 208 ? 70.784  63.233  47.910  1.00 32.44  ? 208 TRP F CG  1 
ATOM   11607 C  CD1 . TRP F 1 208 ? 69.829  62.293  48.156  1.00 30.23  ? 208 TRP F CD1 1 
ATOM   11608 C  CD2 . TRP F 1 208 ? 70.136  64.289  47.183  1.00 31.02  ? 208 TRP F CD2 1 
ATOM   11609 N  NE1 . TRP F 1 208 ? 68.621  62.704  47.640  1.00 31.46  ? 208 TRP F NE1 1 
ATOM   11610 C  CE2 . TRP F 1 208 ? 68.784  63.919  47.028  1.00 30.77  ? 208 TRP F CE2 1 
ATOM   11611 C  CE3 . TRP F 1 208 ? 70.571  65.510  46.647  1.00 28.50  ? 208 TRP F CE3 1 
ATOM   11612 C  CZ2 . TRP F 1 208 ? 67.854  64.732  46.373  1.00 27.39  ? 208 TRP F CZ2 1 
ATOM   11613 C  CZ3 . TRP F 1 208 ? 69.656  66.314  45.995  1.00 28.91  ? 208 TRP F CZ3 1 
ATOM   11614 C  CH2 . TRP F 1 208 ? 68.302  65.920  45.865  1.00 28.57  ? 208 TRP F CH2 1 
ATOM   11615 N  N   . ASP F 1 209 ? 72.537  61.990  51.187  1.00 36.19  ? 209 ASP F N   1 
ATOM   11616 C  CA  . ASP F 1 209 ? 72.010  61.110  52.227  1.00 36.06  ? 209 ASP F CA  1 
ATOM   11617 C  C   . ASP F 1 209 ? 72.376  61.564  53.641  1.00 32.33  ? 209 ASP F C   1 
ATOM   11618 O  O   . ASP F 1 209 ? 72.117  60.830  54.593  1.00 36.93  ? 209 ASP F O   1 
ATOM   11619 C  CB  . ASP F 1 209 ? 72.514  59.676  52.007  1.00 38.67  ? 209 ASP F CB  1 
ATOM   11620 C  CG  . ASP F 1 209 ? 71.975  59.048  50.724  1.00 40.85  ? 209 ASP F CG  1 
ATOM   11621 O  OD1 . ASP F 1 209 ? 70.828  59.362  50.316  1.00 42.59  ? 209 ASP F OD1 1 
ATOM   11622 O  OD2 . ASP F 1 209 ? 72.708  58.234  50.128  1.00 42.51  ? 209 ASP F OD2 1 
ATOM   11623 N  N   . GLU F 1 210 ? 72.975  62.744  53.793  1.00 30.89  ? 210 GLU F N   1 
ATOM   11624 C  CA  . GLU F 1 210 ? 73.309  63.311  55.105  1.00 34.19  ? 210 GLU F CA  1 
ATOM   11625 C  C   . GLU F 1 210 ? 74.262  62.397  55.879  1.00 35.28  ? 210 GLU F C   1 
ATOM   11626 O  O   . GLU F 1 210 ? 74.149  62.217  57.093  1.00 38.76  ? 210 GLU F O   1 
ATOM   11627 C  CB  . GLU F 1 210 ? 72.036  63.637  55.897  1.00 29.23  ? 210 GLU F CB  1 
ATOM   11628 C  CG  . GLU F 1 210 ? 71.081  64.478  55.051  1.00 26.94  ? 210 GLU F CG  1 
ATOM   11629 C  CD  . GLU F 1 210 ? 69.870  65.022  55.797  1.00 33.56  ? 210 GLU F CD  1 
ATOM   11630 O  OE1 . GLU F 1 210 ? 69.471  64.452  56.859  1.00 27.00  ? 210 GLU F OE1 1 
ATOM   11631 O  OE2 . GLU F 1 210 ? 69.307  66.028  55.288  1.00 28.00  ? 210 GLU F OE2 1 
ATOM   11632 N  N   . LYS F 1 211 ? 75.221  61.821  55.155  1.00 37.23  ? 211 LYS F N   1 
ATOM   11633 C  CA  . LYS F 1 211 ? 76.335  61.086  55.734  1.00 39.80  ? 211 LYS F CA  1 
ATOM   11634 C  C   . LYS F 1 211 ? 77.652  61.836  55.575  1.00 40.90  ? 211 LYS F C   1 
ATOM   11635 O  O   . LYS F 1 211 ? 78.713  61.295  55.899  1.00 43.38  ? 211 LYS F O   1 
ATOM   11636 C  CB  . LYS F 1 211 ? 76.441  59.704  55.092  1.00 39.15  ? 211 LYS F CB  1 
ATOM   11637 C  CG  . LYS F 1 211 ? 75.261  58.780  55.358  1.00 36.28  ? 211 LYS F CG  1 
ATOM   11638 C  CD  . LYS F 1 211 ? 75.250  57.645  54.333  1.00 46.86  ? 211 LYS F CD  1 
ATOM   11639 C  CE  . LYS F 1 211 ? 74.119  56.658  54.562  1.00 53.23  ? 211 LYS F CE  1 
ATOM   11640 N  NZ  . LYS F 1 211 ? 73.995  55.701  53.423  1.00 51.53  ? 211 LYS F NZ  1 
ATOM   11641 N  N   . ALA F 1 212 ? 77.613  63.063  55.071  1.00 35.19  ? 212 ALA F N   1 
ATOM   11642 C  CA  . ALA F 1 212 ? 78.825  63.825  54.831  1.00 34.96  ? 212 ALA F CA  1 
ATOM   11643 C  C   . ALA F 1 212 ? 78.462  65.294  54.673  1.00 40.70  ? 212 ALA F C   1 
ATOM   11644 O  O   . ALA F 1 212 ? 77.463  65.633  54.023  1.00 37.17  ? 212 ALA F O   1 
ATOM   11645 C  CB  . ALA F 1 212 ? 79.564  63.333  53.580  1.00 37.07  ? 212 ALA F CB  1 
ATOM   11646 N  N   . LEU F 1 213 ? 79.272  66.140  55.251  1.00 34.49  ? 213 LEU F N   1 
ATOM   11647 C  CA  . LEU F 1 213 ? 79.214  67.563  55.016  1.00 34.86  ? 213 LEU F CA  1 
ATOM   11648 C  C   . LEU F 1 213 ? 80.239  67.960  53.961  1.00 39.33  ? 213 LEU F C   1 
ATOM   11649 O  O   . LEU F 1 213 ? 81.258  67.290  53.801  1.00 38.09  ? 213 LEU F O   1 
ATOM   11650 C  CB  . LEU F 1 213 ? 79.498  68.324  56.310  1.00 32.16  ? 213 LEU F CB  1 
ATOM   11651 C  CG  . LEU F 1 213 ? 78.530  68.064  57.460  1.00 36.30  ? 213 LEU F CG  1 
ATOM   11652 C  CD1 . LEU F 1 213 ? 78.973  68.779  58.746  1.00 30.57  ? 213 LEU F CD1 1 
ATOM   11653 C  CD2 . LEU F 1 213 ? 77.121  68.472  57.048  1.00 32.77  ? 213 LEU F CD2 1 
ATOM   11654 N  N   . PRO F 1 214 ? 80.014  69.049  53.230  1.00 38.42  ? 214 PRO F N   1 
ATOM   11655 C  CA  . PRO F 1 214 ? 81.040  69.517  52.287  1.00 40.65  ? 214 PRO F CA  1 
ATOM   11656 C  C   . PRO F 1 214 ? 82.349  69.816  53.011  1.00 45.95  ? 214 PRO F C   1 
ATOM   11657 O  O   . PRO F 1 214 ? 82.358  70.272  54.157  1.00 44.19  ? 214 PRO F O   1 
ATOM   11658 C  CB  . PRO F 1 214 ? 80.430  70.789  51.683  1.00 41.79  ? 214 PRO F CB  1 
ATOM   11659 C  CG  . PRO F 1 214 ? 79.026  70.881  52.186  1.00 36.09  ? 214 PRO F CG  1 
ATOM   11660 C  CD  . PRO F 1 214 ? 78.841  69.941  53.313  1.00 34.27  ? 214 PRO F CD  1 
ATOM   11661 N  N   . GLY F 1 215 ? 83.469  69.535  52.333  1.00 44.44  ? 215 GLY F N   1 
ATOM   11662 C  CA  . GLY F 1 215 ? 84.775  69.829  52.901  1.00 44.39  ? 215 GLY F CA  1 
ATOM   11663 C  C   . GLY F 1 215 ? 85.200  71.271  52.764  1.00 45.97  ? 215 GLY F C   1 
ATOM   11664 O  O   . GLY F 1 215 ? 86.136  71.704  53.446  1.00 51.30  ? 215 GLY F O   1 
ATOM   11665 N  N   . PHE F 1 216 ? 84.540  72.017  51.885  1.00 45.14  ? 216 PHE F N   1 
ATOM   11666 C  CA  . PHE F 1 216 ? 84.698  73.455  51.767  1.00 43.44  ? 216 PHE F CA  1 
ATOM   11667 C  C   . PHE F 1 216 ? 83.307  74.070  51.783  1.00 40.63  ? 216 PHE F C   1 
ATOM   11668 O  O   . PHE F 1 216 ? 82.444  73.657  51.002  1.00 39.39  ? 216 PHE F O   1 
ATOM   11669 C  CB  . PHE F 1 216 ? 85.437  73.842  50.475  1.00 40.82  ? 216 PHE F CB  1 
ATOM   11670 C  CG  . PHE F 1 216 ? 85.549  75.334  50.269  1.00 47.73  ? 216 PHE F CG  1 
ATOM   11671 C  CD1 . PHE F 1 216 ? 84.464  76.079  49.812  1.00 51.14  ? 216 PHE F CD1 1 
ATOM   11672 C  CD2 . PHE F 1 216 ? 86.729  75.994  50.555  1.00 45.86  ? 216 PHE F CD2 1 
ATOM   11673 C  CE1 . PHE F 1 216 ? 84.563  77.444  49.642  1.00 55.43  ? 216 PHE F CE1 1 
ATOM   11674 C  CE2 . PHE F 1 216 ? 86.838  77.354  50.377  1.00 43.29  ? 216 PHE F CE2 1 
ATOM   11675 C  CZ  . PHE F 1 216 ? 85.758  78.080  49.916  1.00 47.61  ? 216 PHE F CZ  1 
ATOM   11676 N  N   . LEU F 1 217 ? 83.095  75.077  52.632  1.00 36.66  ? 217 LEU F N   1 
ATOM   11677 C  CA  . LEU F 1 217 ? 81.760  75.654  52.718  1.00 34.86  ? 217 LEU F CA  1 
ATOM   11678 C  C   . LEU F 1 217 ? 81.799  77.015  53.400  1.00 32.05  ? 217 LEU F C   1 
ATOM   11679 O  O   . LEU F 1 217 ? 82.697  77.313  54.191  1.00 32.50  ? 217 LEU F O   1 
ATOM   11680 C  CB  . LEU F 1 217 ? 80.800  74.695  53.439  1.00 27.10  ? 217 LEU F CB  1 
ATOM   11681 C  CG  . LEU F 1 217 ? 80.789  74.531  54.955  1.00 33.28  ? 217 LEU F CG  1 
ATOM   11682 C  CD1 . LEU F 1 217 ? 79.811  73.414  55.298  1.00 31.90  ? 217 LEU F CD1 1 
ATOM   11683 C  CD2 . LEU F 1 217 ? 82.179  74.232  55.552  1.00 34.27  ? 217 LEU F CD2 1 
ATOM   11684 N  N   . ALA F 1 218 ? 80.821  77.843  53.057  1.00 30.88  ? 218 ALA F N   1 
ATOM   11685 C  CA  . ALA F 1 218 ? 80.637  79.133  53.706  1.00 27.19  ? 218 ALA F CA  1 
ATOM   11686 C  C   . ALA F 1 218 ? 79.730  79.029  54.931  1.00 24.50  ? 218 ALA F C   1 
ATOM   11687 O  O   . ALA F 1 218 ? 79.991  79.678  55.953  1.00 25.57  ? 218 ALA F O   1 
ATOM   11688 C  CB  . ALA F 1 218 ? 80.069  80.139  52.703  1.00 24.15  ? 218 ALA F CB  1 
ATOM   11689 N  N   . SER F 1 219 ? 78.662  78.234  54.848  1.00 24.06  ? 219 SER F N   1 
ATOM   11690 C  CA  . SER F 1 219 ? 77.729  78.053  55.959  1.00 22.42  ? 219 SER F CA  1 
ATOM   11691 C  C   . SER F 1 219 ? 77.233  76.614  55.977  1.00 24.82  ? 219 SER F C   1 
ATOM   11692 O  O   . SER F 1 219 ? 76.615  76.158  55.007  1.00 25.09  ? 219 SER F O   1 
ATOM   11693 C  CB  . SER F 1 219 ? 76.538  79.012  55.851  1.00 22.02  ? 219 SER F CB  1 
ATOM   11694 O  OG  . SER F 1 219 ? 75.506  78.625  56.743  1.00 22.91  ? 219 SER F OG  1 
ATOM   11695 N  N   . THR F 1 220 ? 77.463  75.920  57.098  1.00 24.93  ? 220 THR F N   1 
ATOM   11696 C  CA  . THR F 1 220 ? 76.981  74.548  57.247  1.00 24.30  ? 220 THR F CA  1 
ATOM   11697 C  C   . THR F 1 220 ? 75.476  74.505  57.428  1.00 23.28  ? 220 THR F C   1 
ATOM   11698 O  O   . THR F 1 220 ? 74.803  73.617  56.885  1.00 22.63  ? 220 THR F O   1 
ATOM   11699 C  CB  . THR F 1 220 ? 77.659  73.878  58.444  1.00 24.92  ? 220 THR F CB  1 
ATOM   11700 O  OG1 . THR F 1 220 ? 79.063  74.155  58.412  1.00 29.02  ? 220 THR F OG1 1 
ATOM   11701 C  CG2 . THR F 1 220 ? 77.430  72.379  58.410  1.00 24.31  ? 220 THR F CG2 1 
ATOM   11702 N  N   . VAL F 1 221 ? 74.947  75.426  58.240  1.00 23.24  ? 221 VAL F N   1 
ATOM   11703 C  CA  . VAL F 1 221 ? 73.502  75.559  58.406  1.00 20.61  ? 221 VAL F CA  1 
ATOM   11704 C  C   . VAL F 1 221 ? 72.818  75.683  57.042  1.00 22.25  ? 221 VAL F C   1 
ATOM   11705 O  O   . VAL F 1 221 ? 71.885  74.935  56.715  1.00 21.17  ? 221 VAL F O   1 
ATOM   11706 C  CB  . VAL F 1 221 ? 73.191  76.764  59.316  1.00 22.12  ? 221 VAL F CB  1 
ATOM   11707 C  CG1 . VAL F 1 221 ? 71.711  77.069  59.360  1.00 23.45  ? 221 VAL F CG1 1 
ATOM   11708 C  CG2 . VAL F 1 221 ? 73.721  76.518  60.726  1.00 25.56  ? 221 VAL F CG2 1 
ATOM   11709 N  N   . ASP F 1 222 ? 73.290  76.612  56.210  1.00 22.18  ? 222 ASP F N   1 
ATOM   11710 C  CA  . ASP F 1 222 ? 72.619  76.822  54.933  1.00 20.41  ? 222 ASP F CA  1 
ATOM   11711 C  C   . ASP F 1 222 ? 72.810  75.620  54.013  1.00 24.47  ? 222 ASP F C   1 
ATOM   11712 O  O   . ASP F 1 222 ? 71.888  75.239  53.281  1.00 22.90  ? 222 ASP F O   1 
ATOM   11713 C  CB  . ASP F 1 222 ? 73.133  78.097  54.275  1.00 25.23  ? 222 ASP F CB  1 
ATOM   11714 C  CG  . ASP F 1 222 ? 72.584  79.370  54.931  1.00 23.12  ? 222 ASP F CG  1 
ATOM   11715 O  OD1 . ASP F 1 222 ? 71.519  79.318  55.569  1.00 27.00  ? 222 ASP F OD1 1 
ATOM   11716 O  OD2 . ASP F 1 222 ? 73.238  80.417  54.813  1.00 23.19  ? 222 ASP F OD2 1 
ATOM   11717 N  N   . ALA F 1 223 ? 73.993  75.002  54.056  1.00 24.08  ? 223 ALA F N   1 
ATOM   11718 C  CA  . ALA F 1 223 ? 74.290  73.865  53.185  1.00 22.74  ? 223 ALA F CA  1 
ATOM   11719 C  C   . ALA F 1 223 ? 73.351  72.695  53.457  1.00 23.41  ? 223 ALA F C   1 
ATOM   11720 O  O   . ALA F 1 223 ? 72.814  72.087  52.524  1.00 28.88  ? 223 ALA F O   1 
ATOM   11721 C  CB  . ALA F 1 223 ? 75.748  73.434  53.369  1.00 15.88  ? 223 ALA F CB  1 
ATOM   11722 N  N   . VAL F 1 224 ? 73.139  72.358  54.731  1.00 19.81  ? 224 VAL F N   1 
ATOM   11723 C  CA  . VAL F 1 224 ? 72.296  71.200  55.023  1.00 24.18  ? 224 VAL F CA  1 
ATOM   11724 C  C   . VAL F 1 224 ? 70.822  71.520  54.757  1.00 26.34  ? 224 VAL F C   1 
ATOM   11725 O  O   . VAL F 1 224 ? 70.051  70.646  54.326  1.00 24.42  ? 224 VAL F O   1 
ATOM   11726 C  CB  . VAL F 1 224 ? 72.516  70.696  56.463  1.00 23.97  ? 224 VAL F CB  1 
ATOM   11727 C  CG1 . VAL F 1 224 ? 73.957  70.213  56.660  1.00 22.28  ? 224 VAL F CG1 1 
ATOM   11728 C  CG2 . VAL F 1 224 ? 72.188  71.804  57.464  1.00 25.71  ? 224 VAL F CG2 1 
ATOM   11729 N  N   . ARG F 1 225 ? 70.398  72.759  55.030  1.00 24.16  ? 225 ARG F N   1 
ATOM   11730 C  CA  . ARG F 1 225 ? 69.014  73.132  54.733  1.00 23.38  ? 225 ARG F CA  1 
ATOM   11731 C  C   . ARG F 1 225 ? 68.767  73.186  53.232  1.00 24.44  ? 225 ARG F C   1 
ATOM   11732 O  O   . ARG F 1 225 ? 67.671  72.849  52.772  1.00 20.42  ? 225 ARG F O   1 
ATOM   11733 C  CB  . ARG F 1 225 ? 68.673  74.472  55.380  1.00 21.18  ? 225 ARG F CB  1 
ATOM   11734 C  CG  . ARG F 1 225 ? 68.745  74.413  56.896  1.00 25.81  ? 225 ARG F CG  1 
ATOM   11735 C  CD  . ARG F 1 225 ? 68.383  75.740  57.588  1.00 21.83  ? 225 ARG F CD  1 
ATOM   11736 N  NE  . ARG F 1 225 ? 68.411  75.587  59.042  1.00 23.46  ? 225 ARG F NE  1 
ATOM   11737 C  CZ  . ARG F 1 225 ? 68.213  76.573  59.908  1.00 27.26  ? 225 ARG F CZ  1 
ATOM   11738 N  NH1 . ARG F 1 225 ? 67.910  77.801  59.501  1.00 23.72  ? 225 ARG F NH1 1 
ATOM   11739 N  NH2 . ARG F 1 225 ? 68.322  76.323  61.214  1.00 22.10  ? 225 ARG F NH2 1 
ATOM   11740 N  N   . SER F 1 226 ? 69.784  73.586  52.457  1.00 21.54  ? 226 SER F N   1 
ATOM   11741 C  CA  . SER F 1 226 ? 69.667  73.559  51.009  1.00 22.38  ? 226 SER F CA  1 
ATOM   11742 C  C   . SER F 1 226 ? 69.507  72.136  50.491  1.00 24.05  ? 226 SER F C   1 
ATOM   11743 O  O   . SER F 1 226 ? 68.770  71.910  49.521  1.00 24.61  ? 226 SER F O   1 
ATOM   11744 C  CB  . SER F 1 226 ? 70.885  74.230  50.352  1.00 25.23  ? 226 SER F CB  1 
ATOM   11745 O  OG  . SER F 1 226 ? 70.853  75.647  50.488  1.00 24.01  ? 226 SER F OG  1 
ATOM   11746 N  N   . VAL F 1 227 ? 70.221  71.171  51.088  1.00 23.04  ? 227 VAL F N   1 
ATOM   11747 C  CA  . VAL F 1 227 ? 70.076  69.780  50.657  1.00 24.55  ? 227 VAL F CA  1 
ATOM   11748 C  C   . VAL F 1 227 ? 68.645  69.313  50.884  1.00 24.39  ? 227 VAL F C   1 
ATOM   11749 O  O   . VAL F 1 227 ? 68.005  68.739  49.993  1.00 25.05  ? 227 VAL F O   1 
ATOM   11750 C  CB  . VAL F 1 227 ? 71.082  68.862  51.385  1.00 24.79  ? 227 VAL F CB  1 
ATOM   11751 C  CG1 . VAL F 1 227 ? 70.720  67.409  51.149  1.00 23.98  ? 227 VAL F CG1 1 
ATOM   11752 C  CG2 . VAL F 1 227 ? 72.505  69.108  50.920  1.00 22.17  ? 227 VAL F CG2 1 
ATOM   11753 N  N   . ARG F 1 228 ? 68.118  69.570  52.079  1.00 23.40  ? 228 ARG F N   1 
ATOM   11754 C  CA  . ARG F 1 228 ? 66.745  69.192  52.379  1.00 25.14  ? 228 ARG F CA  1 
ATOM   11755 C  C   . ARG F 1 228 ? 65.761  69.913  51.476  1.00 23.70  ? 228 ARG F C   1 
ATOM   11756 O  O   . ARG F 1 228 ? 64.678  69.394  51.201  1.00 27.22  ? 228 ARG F O   1 
ATOM   11757 C  CB  . ARG F 1 228 ? 66.440  69.485  53.843  1.00 25.44  ? 228 ARG F CB  1 
ATOM   11758 C  CG  . ARG F 1 228 ? 67.241  68.605  54.775  1.00 27.13  ? 228 ARG F CG  1 
ATOM   11759 C  CD  . ARG F 1 228 ? 66.477  68.280  56.039  1.00 28.19  ? 228 ARG F CD  1 
ATOM   11760 N  NE  . ARG F 1 228 ? 67.172  67.260  56.808  1.00 28.98  ? 228 ARG F NE  1 
ATOM   11761 C  CZ  . ARG F 1 228 ? 66.806  66.854  58.014  1.00 30.15  ? 228 ARG F CZ  1 
ATOM   11762 N  NH1 . ARG F 1 228 ? 65.787  67.403  58.645  1.00 33.12  ? 228 ARG F NH1 1 
ATOM   11763 N  NH2 . ARG F 1 228 ? 67.485  65.875  58.604  1.00 27.55  ? 228 ARG F NH2 1 
ATOM   11764 N  N   . LYS F 1 229 ? 66.109  71.113  51.012  1.00 25.50  ? 229 LYS F N   1 
ATOM   11765 C  CA  . LYS F 1 229 ? 65.253  71.788  50.045  1.00 26.11  ? 229 LYS F CA  1 
ATOM   11766 C  C   . LYS F 1 229 ? 65.285  71.054  48.709  1.00 25.15  ? 229 LYS F C   1 
ATOM   11767 O  O   . LYS F 1 229 ? 64.257  70.917  48.037  1.00 24.88  ? 229 LYS F O   1 
ATOM   11768 C  CB  . LYS F 1 229 ? 65.691  73.253  49.905  1.00 24.25  ? 229 LYS F CB  1 
ATOM   11769 C  CG  . LYS F 1 229 ? 65.092  74.019  48.734  1.00 22.03  ? 229 LYS F CG  1 
ATOM   11770 C  CD  . LYS F 1 229 ? 65.647  75.441  48.678  1.00 21.93  ? 229 LYS F CD  1 
ATOM   11771 C  CE  . LYS F 1 229 ? 64.975  76.296  47.596  1.00 20.61  ? 229 LYS F CE  1 
ATOM   11772 N  NZ  . LYS F 1 229 ? 65.639  77.654  47.544  1.00 23.50  ? 229 LYS F NZ  1 
ATOM   11773 N  N   . LEU F 1 230 ? 66.461  70.564  48.313  1.00 28.47  ? 230 LEU F N   1 
ATOM   11774 C  CA  . LEU F 1 230 ? 66.544  69.753  47.107  1.00 27.70  ? 230 LEU F CA  1 
ATOM   11775 C  C   . LEU F 1 230 ? 65.836  68.406  47.280  1.00 26.06  ? 230 LEU F C   1 
ATOM   11776 O  O   . LEU F 1 230 ? 65.268  67.884  46.309  1.00 26.26  ? 230 LEU F O   1 
ATOM   11777 C  CB  . LEU F 1 230 ? 68.005  69.544  46.713  1.00 22.52  ? 230 LEU F CB  1 
ATOM   11778 C  CG  . LEU F 1 230 ? 68.763  70.796  46.288  1.00 24.60  ? 230 LEU F CG  1 
ATOM   11779 C  CD1 . LEU F 1 230 ? 70.180  70.433  45.847  1.00 21.88  ? 230 LEU F CD1 1 
ATOM   11780 C  CD2 . LEU F 1 230 ? 68.031  71.582  45.191  1.00 23.34  ? 230 LEU F CD2 1 
ATOM   11781 N  N   . HIS F 1 231 ? 65.860  67.824  48.484  1.00 23.89  ? 231 HIS F N   1 
ATOM   11782 C  CA  . HIS F 1 231 ? 65.093  66.601  48.699  1.00 23.77  ? 231 HIS F CA  1 
ATOM   11783 C  C   . HIS F 1 231 ? 63.636  66.834  48.348  1.00 26.82  ? 231 HIS F C   1 
ATOM   11784 O  O   . HIS F 1 231 ? 63.016  66.039  47.630  1.00 28.24  ? 231 HIS F O   1 
ATOM   11785 C  CB  . HIS F 1 231 ? 65.195  66.129  50.148  1.00 26.88  ? 231 HIS F CB  1 
ATOM   11786 C  CG  . HIS F 1 231 ? 66.542  65.620  50.539  1.00 25.70  ? 231 HIS F CG  1 
ATOM   11787 N  ND1 . HIS F 1 231 ? 66.888  65.389  51.853  1.00 27.96  ? 231 HIS F ND1 1 
ATOM   11788 C  CD2 . HIS F 1 231 ? 67.626  65.295  49.798  1.00 27.44  ? 231 HIS F CD2 1 
ATOM   11789 C  CE1 . HIS F 1 231 ? 68.133  64.953  51.904  1.00 27.41  ? 231 HIS F CE1 1 
ATOM   11790 N  NE2 . HIS F 1 231 ? 68.605  64.892  50.671  1.00 29.17  ? 231 HIS F NE2 1 
ATOM   11791 N  N   . ALA F 1 232 ? 63.079  67.944  48.838  1.00 27.45  ? 232 ALA F N   1 
ATOM   11792 C  CA  . ALA F 1 232 ? 61.676  68.242  48.615  1.00 25.09  ? 232 ALA F CA  1 
ATOM   11793 C  C   . ALA F 1 232 ? 61.403  68.480  47.145  1.00 26.89  ? 232 ALA F C   1 
ATOM   11794 O  O   . ALA F 1 232 ? 60.358  68.069  46.625  1.00 22.25  ? 232 ALA F O   1 
ATOM   11795 C  CB  . ALA F 1 232 ? 61.271  69.456  49.442  1.00 28.95  ? 232 ALA F CB  1 
ATOM   11796 N  N   . LEU F 1 233 ? 62.346  69.124  46.453  1.00 25.71  ? 233 LEU F N   1 
ATOM   11797 C  CA  . LEU F 1 233 ? 62.186  69.352  45.022  1.00 27.17  ? 233 LEU F CA  1 
ATOM   11798 C  C   . LEU F 1 233 ? 62.265  68.037  44.248  1.00 27.75  ? 233 LEU F C   1 
ATOM   11799 O  O   . LEU F 1 233 ? 61.453  67.788  43.347  1.00 28.16  ? 233 LEU F O   1 
ATOM   11800 C  CB  . LEU F 1 233 ? 63.245  70.339  44.533  1.00 25.20  ? 233 LEU F CB  1 
ATOM   11801 C  CG  . LEU F 1 233 ? 63.056  70.871  43.116  1.00 26.72  ? 233 LEU F CG  1 
ATOM   11802 C  CD1 . LEU F 1 233 ? 61.720  71.569  43.016  1.00 26.70  ? 233 LEU F CD1 1 
ATOM   11803 C  CD2 . LEU F 1 233 ? 64.169  71.830  42.756  1.00 26.11  ? 233 LEU F CD2 1 
ATOM   11804 N  N   . ALA F 1 234 ? 63.238  67.188  44.593  1.00 30.46  ? 234 ALA F N   1 
ATOM   11805 C  CA  . ALA F 1 234 ? 63.355  65.874  43.968  1.00 28.89  ? 234 ALA F CA  1 
ATOM   11806 C  C   . ALA F 1 234 ? 62.116  65.029  44.211  1.00 27.86  ? 234 ALA F C   1 
ATOM   11807 O  O   . ALA F 1 234 ? 61.626  64.368  43.291  1.00 27.83  ? 234 ALA F O   1 
ATOM   11808 C  CB  . ALA F 1 234 ? 64.589  65.142  44.495  1.00 27.85  ? 234 ALA F CB  1 
ATOM   11809 N  N   . GLU F 1 235 ? 61.602  65.018  45.449  1.00 24.48  ? 235 GLU F N   1 
ATOM   11810 C  CA  . GLU F 1 235 ? 60.422  64.204  45.726  1.00 25.83  ? 235 GLU F CA  1 
ATOM   11811 C  C   . GLU F 1 235 ? 59.178  64.743  45.020  1.00 33.32  ? 235 GLU F C   1 
ATOM   11812 O  O   . GLU F 1 235 ? 58.294  63.961  44.645  1.00 32.78  ? 235 GLU F O   1 
ATOM   11813 C  CB  . GLU F 1 235 ? 60.187  64.111  47.239  1.00 27.77  ? 235 GLU F CB  1 
ATOM   11814 C  CG  . GLU F 1 235 ? 59.069  63.158  47.656  1.00 23.20  ? 235 GLU F CG  1 
ATOM   11815 C  CD  . GLU F 1 235 ? 57.674  63.771  47.541  1.00 31.43  ? 235 GLU F CD  1 
ATOM   11816 O  OE1 . GLU F 1 235 ? 57.575  64.999  47.341  1.00 34.71  ? 235 GLU F OE1 1 
ATOM   11817 O  OE2 . GLU F 1 235 ? 56.668  63.035  47.641  1.00 31.02  ? 235 GLU F OE2 1 
ATOM   11818 N  N   . LYS F 1 236 ? 59.082  66.066  44.834  1.00 29.66  ? 236 LYS F N   1 
ATOM   11819 C  CA  . LYS F 1 236 ? 57.889  66.648  44.223  1.00 31.48  ? 236 LYS F CA  1 
ATOM   11820 C  C   . LYS F 1 236 ? 57.885  66.461  42.710  1.00 28.53  ? 236 LYS F C   1 
ATOM   11821 O  O   . LYS F 1 236 ? 56.836  66.181  42.127  1.00 31.79  ? 236 LYS F O   1 
ATOM   11822 C  CB  . LYS F 1 236 ? 57.788  68.136  44.572  1.00 31.15  ? 236 LYS F CB  1 
ATOM   11823 C  CG  . LYS F 1 236 ? 56.980  69.000  43.587  1.00 27.82  ? 236 LYS F CG  1 
ATOM   11824 C  CD  . LYS F 1 236 ? 57.021  70.476  44.030  1.00 27.95  ? 236 LYS F CD  1 
ATOM   11825 C  CE  . LYS F 1 236 ? 56.234  71.377  43.078  1.00 29.03  ? 236 LYS F CE  1 
ATOM   11826 N  NZ  . LYS F 1 236 ? 56.091  72.803  43.573  1.00 26.41  ? 236 LYS F NZ  1 
ATOM   11827 N  N   . THR F 1 237 ? 59.036  66.621  42.065  1.00 29.07  ? 237 THR F N   1 
ATOM   11828 C  CA  . THR F 1 237 ? 59.140  66.553  40.613  1.00 26.54  ? 237 THR F CA  1 
ATOM   11829 C  C   . THR F 1 237 ? 59.505  65.163  40.090  1.00 33.16  ? 237 THR F C   1 
ATOM   11830 O  O   . THR F 1 237 ? 59.372  64.925  38.886  1.00 32.31  ? 237 THR F O   1 
ATOM   11831 C  CB  . THR F 1 237 ? 60.200  67.536  40.106  1.00 31.16  ? 237 THR F CB  1 
ATOM   11832 O  OG1 . THR F 1 237 ? 61.475  67.178  40.655  1.00 30.40  ? 237 THR F OG1 1 
ATOM   11833 C  CG2 . THR F 1 237 ? 59.872  68.968  40.497  1.00 29.60  ? 237 THR F CG2 1 
ATOM   11834 N  N   . GLY F 1 238 ? 59.989  64.256  40.940  1.00 28.79  ? 238 GLY F N   1 
ATOM   11835 C  CA  . GLY F 1 238 ? 60.596  63.030  40.436  1.00 32.09  ? 238 GLY F CA  1 
ATOM   11836 C  C   . GLY F 1 238 ? 61.862  63.259  39.635  1.00 34.81  ? 238 GLY F C   1 
ATOM   11837 O  O   . GLY F 1 238 ? 62.186  62.461  38.745  1.00 36.49  ? 238 GLY F O   1 
ATOM   11838 N  N   . ALA F 1 239 ? 62.585  64.337  39.917  1.00 28.50  ? 239 ALA F N   1 
ATOM   11839 C  CA  . ALA F 1 239 ? 63.721  64.688  39.084  1.00 30.00  ? 239 ALA F CA  1 
ATOM   11840 C  C   . ALA F 1 239 ? 64.804  63.620  39.145  1.00 32.29  ? 239 ALA F C   1 
ATOM   11841 O  O   . ALA F 1 239 ? 64.970  62.916  40.141  1.00 32.49  ? 239 ALA F O   1 
ATOM   11842 C  CB  . ALA F 1 239 ? 64.309  66.031  39.508  1.00 30.07  ? 239 ALA F CB  1 
ATOM   11843 N  N   . LEU F 1 240 ? 65.532  63.499  38.046  1.00 33.43  ? 240 LEU F N   1 
ATOM   11844 C  CA  . LEU F 1 240 ? 66.818  62.823  38.065  1.00 33.37  ? 240 LEU F CA  1 
ATOM   11845 C  C   . LEU F 1 240 ? 67.832  63.718  38.770  1.00 32.64  ? 240 LEU F C   1 
ATOM   11846 O  O   . LEU F 1 240 ? 68.088  64.845  38.325  1.00 31.01  ? 240 LEU F O   1 
ATOM   11847 C  CB  . LEU F 1 240 ? 67.269  62.519  36.635  1.00 29.34  ? 240 LEU F CB  1 
ATOM   11848 C  CG  . LEU F 1 240 ? 68.619  61.806  36.546  1.00 32.96  ? 240 LEU F CG  1 
ATOM   11849 C  CD1 . LEU F 1 240 ? 68.474  60.398  37.096  1.00 31.84  ? 240 LEU F CD1 1 
ATOM   11850 C  CD2 . LEU F 1 240 ? 69.158  61.783  35.123  1.00 36.51  ? 240 LEU F CD2 1 
ATOM   11851 N  N   . VAL F 1 241 ? 68.426  63.223  39.846  1.00 30.89  ? 241 VAL F N   1 
ATOM   11852 C  CA  . VAL F 1 241 ? 69.376  64.011  40.627  1.00 31.06  ? 241 VAL F CA  1 
ATOM   11853 C  C   . VAL F 1 241 ? 70.797  63.766  40.126  1.00 34.45  ? 241 VAL F C   1 
ATOM   11854 O  O   . VAL F 1 241 ? 71.307  62.642  40.204  1.00 32.77  ? 241 VAL F O   1 
ATOM   11855 C  CB  . VAL F 1 241 ? 69.258  63.687  42.122  1.00 32.45  ? 241 VAL F CB  1 
ATOM   11856 C  CG1 . VAL F 1 241 ? 70.159  64.617  42.944  1.00 32.26  ? 241 VAL F CG1 1 
ATOM   11857 C  CG2 . VAL F 1 241 ? 67.812  63.797  42.567  1.00 31.77  ? 241 VAL F CG2 1 
ATOM   11858 N  N   . VAL F 1 242 ? 71.453  64.833  39.664  1.00 35.56  ? 242 VAL F N   1 
ATOM   11859 C  CA  . VAL F 1 242 ? 72.846  64.811  39.229  1.00 30.15  ? 242 VAL F CA  1 
ATOM   11860 C  C   . VAL F 1 242 ? 73.708  65.483  40.300  1.00 34.46  ? 242 VAL F C   1 
ATOM   11861 O  O   . VAL F 1 242 ? 73.660  66.708  40.468  1.00 34.40  ? 242 VAL F O   1 
ATOM   11862 C  CB  . VAL F 1 242 ? 73.025  65.523  37.884  1.00 33.59  ? 242 VAL F CB  1 
ATOM   11863 C  CG1 . VAL F 1 242 ? 74.447  65.317  37.356  1.00 29.99  ? 242 VAL F CG1 1 
ATOM   11864 C  CG2 . VAL F 1 242 ? 71.965  65.072  36.890  1.00 33.76  ? 242 VAL F CG2 1 
ATOM   11865 N  N   . TYR F 1 243 ? 74.547  64.703  40.981  1.00 35.28  ? 243 TYR F N   1 
ATOM   11866 C  CA  . TYR F 1 243 ? 75.443  65.237  42.003  1.00 36.56  ? 243 TYR F CA  1 
ATOM   11867 C  C   . TYR F 1 243 ? 76.657  65.924  41.371  1.00 39.52  ? 243 TYR F C   1 
ATOM   11868 O  O   . TYR F 1 243 ? 77.058  65.636  40.236  1.00 40.32  ? 243 TYR F O   1 
ATOM   11869 C  CB  . TYR F 1 243 ? 75.887  64.129  42.957  1.00 35.25  ? 243 TYR F CB  1 
ATOM   11870 C  CG  . TYR F 1 243 ? 74.759  63.207  43.361  1.00 36.95  ? 243 TYR F CG  1 
ATOM   11871 C  CD1 . TYR F 1 243 ? 73.973  63.476  44.475  1.00 35.32  ? 243 TYR F CD1 1 
ATOM   11872 C  CD2 . TYR F 1 243 ? 74.460  62.075  42.609  1.00 40.91  ? 243 TYR F CD2 1 
ATOM   11873 C  CE1 . TYR F 1 243 ? 72.931  62.626  44.842  1.00 39.13  ? 243 TYR F CE1 1 
ATOM   11874 C  CE2 . TYR F 1 243 ? 73.427  61.227  42.963  1.00 33.64  ? 243 TYR F CE2 1 
ATOM   11875 C  CZ  . TYR F 1 243 ? 72.668  61.500  44.076  1.00 39.81  ? 243 TYR F CZ  1 
ATOM   11876 O  OH  . TYR F 1 243 ? 71.643  60.641  44.418  1.00 42.58  ? 243 TYR F OH  1 
ATOM   11877 N  N   . GLY F 1 244 ? 77.251  66.847  42.134  1.00 35.96  ? 244 GLY F N   1 
ATOM   11878 C  CA  . GLY F 1 244 ? 78.175  67.797  41.541  1.00 36.64  ? 244 GLY F CA  1 
ATOM   11879 C  C   . GLY F 1 244 ? 79.585  67.298  41.328  1.00 39.14  ? 244 GLY F C   1 
ATOM   11880 O  O   . GLY F 1 244 ? 80.258  67.742  40.393  1.00 43.36  ? 244 GLY F O   1 
ATOM   11881 N  N   . HIS F 1 245 ? 80.060  66.399  42.182  1.00 40.02  ? 245 HIS F N   1 
ATOM   11882 C  CA  . HIS F 1 245 ? 81.443  65.931  42.160  1.00 40.33  ? 245 HIS F CA  1 
ATOM   11883 C  C   . HIS F 1 245 ? 81.491  64.501  42.696  1.00 43.23  ? 245 HIS F C   1 
ATOM   11884 O  O   . HIS F 1 245 ? 82.145  64.187  43.686  1.00 41.34  ? 245 HIS F O   1 
ATOM   11885 C  CB  . HIS F 1 245 ? 82.338  66.856  42.985  1.00 38.84  ? 245 HIS F CB  1 
ATOM   11886 C  CG  . HIS F 1 245 ? 82.608  68.173  42.338  1.00 40.48  ? 245 HIS F CG  1 
ATOM   11887 N  ND1 . HIS F 1 245 ? 83.060  68.285  41.041  1.00 44.79  ? 245 HIS F ND1 1 
ATOM   11888 C  CD2 . HIS F 1 245 ? 82.485  69.437  42.804  1.00 37.68  ? 245 HIS F CD2 1 
ATOM   11889 C  CE1 . HIS F 1 245 ? 83.214  69.561  40.738  1.00 38.36  ? 245 HIS F CE1 1 
ATOM   11890 N  NE2 . HIS F 1 245 ? 82.870  70.280  41.790  1.00 42.13  ? 245 HIS F NE2 1 
ATOM   11891 N  N   . ASP F 1 246 ? 80.765  63.595  42.065  1.00 42.49  ? 246 ASP F N   1 
ATOM   11892 C  CA  . ASP F 1 246 ? 80.718  62.238  42.580  1.00 44.53  ? 246 ASP F CA  1 
ATOM   11893 C  C   . ASP F 1 246 ? 81.478  61.308  41.643  1.00 46.95  ? 246 ASP F C   1 
ATOM   11894 O  O   . ASP F 1 246 ? 81.039  61.093  40.503  1.00 45.16  ? 246 ASP F O   1 
ATOM   11895 C  CB  . ASP F 1 246 ? 79.272  61.777  42.759  1.00 41.51  ? 246 ASP F CB  1 
ATOM   11896 C  CG  . ASP F 1 246 ? 79.166  60.570  43.663  1.00 47.42  ? 246 ASP F CG  1 
ATOM   11897 O  OD1 . ASP F 1 246 ? 80.074  59.710  43.572  1.00 49.60  ? 246 ASP F OD1 1 
ATOM   11898 O  OD2 . ASP F 1 246 ? 78.204  60.480  44.477  1.00 42.14  ? 246 ASP F OD2 1 
ATOM   11899 N  N   . PRO F 1 247 ? 82.605  60.731  42.073  1.00 50.45  ? 247 PRO F N   1 
ATOM   11900 C  CA  . PRO F 1 247 ? 83.393  59.899  41.149  1.00 48.96  ? 247 PRO F CA  1 
ATOM   11901 C  C   . PRO F 1 247 ? 82.705  58.597  40.792  1.00 49.62  ? 247 PRO F C   1 
ATOM   11902 O  O   . PRO F 1 247 ? 82.980  58.044  39.721  1.00 51.08  ? 247 PRO F O   1 
ATOM   11903 C  CB  . PRO F 1 247 ? 84.706  59.649  41.911  1.00 47.44  ? 247 PRO F CB  1 
ATOM   11904 C  CG  . PRO F 1 247 ? 84.592  60.356  43.217  1.00 44.72  ? 247 PRO F CG  1 
ATOM   11905 C  CD  . PRO F 1 247 ? 83.170  60.756  43.432  1.00 47.32  ? 247 PRO F CD  1 
ATOM   11906 N  N   . GLU F 1 248 ? 81.813  58.102  41.651  1.00 45.55  ? 248 GLU F N   1 
ATOM   11907 C  CA  . GLU F 1 248 ? 81.101  56.856  41.396  1.00 49.38  ? 248 GLU F CA  1 
ATOM   11908 C  C   . GLU F 1 248 ? 79.863  57.071  40.535  1.00 52.62  ? 248 GLU F C   1 
ATOM   11909 O  O   . GLU F 1 248 ? 79.645  56.349  39.556  1.00 50.91  ? 248 GLU F O   1 
ATOM   11910 C  CB  . GLU F 1 248 ? 80.694  56.213  42.715  1.00 50.83  ? 248 GLU F CB  1 
ATOM   11911 C  CG  . GLU F 1 248 ? 81.782  56.130  43.757  1.00 51.78  ? 248 GLU F CG  1 
ATOM   11912 C  CD  . GLU F 1 248 ? 81.279  55.422  44.985  1.00 65.16  ? 248 GLU F CD  1 
ATOM   11913 O  OE1 . GLU F 1 248 ? 80.053  55.160  45.021  1.00 62.95  ? 248 GLU F OE1 1 
ATOM   11914 O  OE2 . GLU F 1 248 ? 82.082  55.137  45.904  1.00 67.97  ? 248 GLU F OE2 1 
ATOM   11915 N  N   . ALA F 1 249 ? 79.014  58.030  40.907  1.00 50.19  ? 249 ALA F N   1 
ATOM   11916 C  CA  . ALA F 1 249 ? 77.759  58.196  40.184  1.00 47.76  ? 249 ALA F CA  1 
ATOM   11917 C  C   . ALA F 1 249 ? 77.967  58.862  38.836  1.00 49.72  ? 249 ALA F C   1 
ATOM   11918 O  O   . ALA F 1 249 ? 77.236  58.562  37.887  1.00 54.93  ? 249 ALA F O   1 
ATOM   11919 C  CB  . ALA F 1 249 ? 76.761  58.996  41.025  1.00 51.94  ? 249 ALA F CB  1 
ATOM   11920 N  N   . TRP F 1 250 ? 78.961  59.739  38.722  1.00 48.00  ? 250 TRP F N   1 
ATOM   11921 C  CA  . TRP F 1 250 ? 79.194  60.438  37.462  1.00 49.50  ? 250 TRP F CA  1 
ATOM   11922 C  C   . TRP F 1 250 ? 79.266  59.511  36.253  1.00 53.32  ? 250 TRP F C   1 
ATOM   11923 O  O   . TRP F 1 250 ? 78.747  59.894  35.190  1.00 49.97  ? 250 TRP F O   1 
ATOM   11924 C  CB  . TRP F 1 250 ? 80.471  61.283  37.569  1.00 44.25  ? 250 TRP F CB  1 
ATOM   11925 C  CG  . TRP F 1 250 ? 80.770  62.100  36.361  1.00 40.07  ? 250 TRP F CG  1 
ATOM   11926 C  CD1 . TRP F 1 250 ? 81.878  62.015  35.577  1.00 44.45  ? 250 TRP F CD1 1 
ATOM   11927 C  CD2 . TRP F 1 250 ? 79.973  63.160  35.814  1.00 42.77  ? 250 TRP F CD2 1 
ATOM   11928 N  NE1 . TRP F 1 250 ? 81.816  62.939  34.560  1.00 44.63  ? 250 TRP F NE1 1 
ATOM   11929 C  CE2 . TRP F 1 250 ? 80.656  63.656  34.685  1.00 38.88  ? 250 TRP F CE2 1 
ATOM   11930 C  CE3 . TRP F 1 250 ? 78.745  63.732  36.165  1.00 43.17  ? 250 TRP F CE3 1 
ATOM   11931 C  CZ2 . TRP F 1 250 ? 80.160  64.695  33.906  1.00 42.06  ? 250 TRP F CZ2 1 
ATOM   11932 C  CZ3 . TRP F 1 250 ? 78.250  64.763  35.388  1.00 43.34  ? 250 TRP F CZ3 1 
ATOM   11933 C  CH2 . TRP F 1 250 ? 78.955  65.233  34.267  1.00 45.10  ? 250 TRP F CH2 1 
ATOM   11934 N  N   . PRO F 1 251 ? 79.879  58.321  36.320  1.00 55.12  ? 251 PRO F N   1 
ATOM   11935 C  CA  . PRO F 1 251 ? 79.805  57.410  35.169  1.00 53.29  ? 251 PRO F CA  1 
ATOM   11936 C  C   . PRO F 1 251 ? 78.410  56.870  34.889  1.00 54.88  ? 251 PRO F C   1 
ATOM   11937 O  O   . PRO F 1 251 ? 78.174  56.416  33.762  1.00 56.65  ? 251 PRO F O   1 
ATOM   11938 C  CB  . PRO F 1 251 ? 80.781  56.294  35.551  1.00 56.28  ? 251 PRO F CB  1 
ATOM   11939 C  CG  . PRO F 1 251 ? 81.782  56.986  36.416  1.00 53.43  ? 251 PRO F CG  1 
ATOM   11940 C  CD  . PRO F 1 251 ? 80.942  57.903  37.253  1.00 51.85  ? 251 PRO F CD  1 
ATOM   11941 N  N   . THR F 1 252 ? 77.477  56.914  35.848  1.00 52.82  ? 252 THR F N   1 
ATOM   11942 C  CA  . THR F 1 252 ? 76.126  56.438  35.558  1.00 54.19  ? 252 THR F CA  1 
ATOM   11943 C  C   . THR F 1 252 ? 75.334  57.396  34.678  1.00 57.64  ? 252 THR F C   1 
ATOM   11944 O  O   . THR F 1 252 ? 74.216  57.051  34.279  1.00 60.12  ? 252 THR F O   1 
ATOM   11945 C  CB  . THR F 1 252 ? 75.326  56.203  36.838  1.00 55.48  ? 252 THR F CB  1 
ATOM   11946 O  OG1 . THR F 1 252 ? 74.999  57.462  37.435  1.00 57.53  ? 252 THR F OG1 1 
ATOM   11947 C  CG2 . THR F 1 252 ? 76.123  55.393  37.827  1.00 55.21  ? 252 THR F CG2 1 
ATOM   11948 N  N   . PHE F 1 253 ? 75.874  58.577  34.368  1.00 58.24  ? 253 PHE F N   1 
ATOM   11949 C  CA  . PHE F 1 253 ? 75.176  59.591  33.593  1.00 57.74  ? 253 PHE F CA  1 
ATOM   11950 C  C   . PHE F 1 253 ? 75.696  59.608  32.159  1.00 58.83  ? 253 PHE F C   1 
ATOM   11951 O  O   . PHE F 1 253 ? 76.660  58.926  31.808  1.00 59.56  ? 253 PHE F O   1 
ATOM   11952 C  CB  . PHE F 1 253 ? 75.317  60.971  34.254  1.00 49.49  ? 253 PHE F CB  1 
ATOM   11953 C  CG  . PHE F 1 253 ? 74.773  61.019  35.645  1.00 52.22  ? 253 PHE F CG  1 
ATOM   11954 C  CD1 . PHE F 1 253 ? 73.406  60.950  35.870  1.00 45.15  ? 253 PHE F CD1 1 
ATOM   11955 C  CD2 . PHE F 1 253 ? 75.631  61.075  36.732  1.00 49.99  ? 253 PHE F CD2 1 
ATOM   11956 C  CE1 . PHE F 1 253 ? 72.896  60.966  37.157  1.00 42.03  ? 253 PHE F CE1 1 
ATOM   11957 C  CE2 . PHE F 1 253 ? 75.128  61.083  38.028  1.00 49.61  ? 253 PHE F CE2 1 
ATOM   11958 C  CZ  . PHE F 1 253 ? 73.754  61.028  38.240  1.00 46.73  ? 253 PHE F CZ  1 
ATOM   11959 N  N   . ARG F 1 254 ? 75.058  60.428  31.332  1.00 53.20  ? 254 ARG F N   1 
ATOM   11960 C  CA  . ARG F 1 254 ? 75.280  60.426  29.900  1.00 49.09  ? 254 ARG F CA  1 
ATOM   11961 C  C   . ARG F 1 254 ? 76.030  61.675  29.431  1.00 53.95  ? 254 ARG F C   1 
ATOM   11962 O  O   . ARG F 1 254 ? 77.082  61.594  28.781  1.00 52.81  ? 254 ARG F O   1 
ATOM   11963 C  CB  . ARG F 1 254 ? 73.923  60.308  29.202  1.00 55.17  ? 254 ARG F CB  1 
ATOM   11964 C  CG  . ARG F 1 254 ? 72.914  59.457  29.983  1.00 59.76  ? 254 ARG F CG  1 
ATOM   11965 C  CD  . ARG F 1 254 ? 71.879  58.792  29.068  1.00 62.04  ? 254 ARG F CD  1 
ATOM   11966 N  NE  . ARG F 1 254 ? 71.513  59.666  27.961  1.00 63.94  ? 254 ARG F NE  1 
ATOM   11967 C  CZ  . ARG F 1 254 ? 70.266  59.974  27.622  1.00 61.81  ? 254 ARG F CZ  1 
ATOM   11968 N  NH1 . ARG F 1 254 ? 69.225  59.383  28.190  1.00 61.34  ? 254 ARG F NH1 1 
ATOM   11969 N  NH2 . ARG F 1 254 ? 70.060  60.899  26.685  1.00 58.79  ? 254 ARG F NH2 1 
HETATM 11970 NI NI  . NI  G 2 .   ? 45.590  78.575  66.191  1.00 40.93  ? 301 NI  A NI  1 
HETATM 11971 NI NI  . NI  H 2 .   ? 42.861  76.712  65.607  1.00 40.09  ? 302 NI  A NI  1 
HETATM 11972 NI NI  . NI  I 2 .   ? 81.330  74.360  71.017  1.00 41.40  ? 301 NI  B NI  1 
HETATM 11973 NI NI  . NI  J 2 .   ? 83.526  73.618  73.405  1.00 44.61  ? 302 NI  B NI  1 
HETATM 11974 NI NI  . NI  K 2 .   ? 58.250  109.954 39.953  1.00 40.61  ? 301 NI  C NI  1 
HETATM 11975 NI NI  . NI  L 2 .   ? 56.749  110.684 36.939  1.00 40.57  ? 302 NI  C NI  1 
HETATM 11976 NI NI  . NI  M 2 .   ? 85.447  113.517 49.164  1.00 45.03  ? 301 NI  D NI  1 
HETATM 11977 NI NI  . NI  N 2 .   ? 83.109  110.978 48.586  1.00 42.14  ? 302 NI  D NI  1 
HETATM 11978 NI NI  . NI  O 2 .   ? 49.861  103.289 74.503  1.00 42.71  ? 301 NI  E NI  1 
HETATM 11979 NI NI  . NI  P 2 .   ? 49.172  104.890 77.459  1.00 42.84  ? 302 NI  E NI  1 
HETATM 11980 NI NI  . NI  Q 2 .   ? 82.540  75.048  44.598  1.00 44.02  ? 301 NI  F NI  1 
HETATM 11981 NI NI  . NI  R 2 .   ? 82.980  72.545  42.395  1.00 43.92  ? 302 NI  F NI  1 
HETATM 11982 O  O   . HOH S 3 .   ? 46.626  50.028  58.251  1.00 42.57  ? 401 HOH A O   1 
HETATM 11983 O  O   . HOH S 3 .   ? 31.315  86.276  63.686  1.00 39.70  ? 402 HOH A O   1 
HETATM 11984 O  O   . HOH S 3 .   ? 32.560  64.802  55.061  1.00 41.89  ? 403 HOH A O   1 
HETATM 11985 O  O   . HOH S 3 .   ? 49.203  55.839  61.767  1.00 29.74  ? 404 HOH A O   1 
HETATM 11986 O  O   . HOH S 3 .   ? 40.544  51.692  55.228  1.00 44.79  ? 405 HOH A O   1 
HETATM 11987 O  O   . HOH S 3 .   ? 43.202  64.005  64.992  1.00 30.39  ? 406 HOH A O   1 
HETATM 11988 O  O   . HOH S 3 .   ? 49.267  71.739  44.128  1.00 26.84  ? 407 HOH A O   1 
HETATM 11989 O  O   . HOH S 3 .   ? 33.533  68.285  52.525  1.00 37.61  ? 408 HOH A O   1 
HETATM 11990 O  O   . HOH S 3 .   ? 29.596  90.041  56.357  1.00 52.68  ? 409 HOH A O   1 
HETATM 11991 O  O   . HOH S 3 .   ? 32.309  81.796  52.074  1.00 30.60  ? 410 HOH A O   1 
HETATM 11992 O  O   . HOH S 3 .   ? 37.231  63.979  62.222  1.00 34.35  ? 411 HOH A O   1 
HETATM 11993 O  O   . HOH S 3 .   ? 43.779  79.209  68.075  1.00 34.11  ? 412 HOH A O   1 
HETATM 11994 O  O   . HOH S 3 .   ? 53.558  67.074  74.562  1.00 32.85  ? 413 HOH A O   1 
HETATM 11995 O  O   . HOH S 3 .   ? 53.594  57.164  61.578  1.00 37.35  ? 414 HOH A O   1 
HETATM 11996 O  O   . HOH S 3 .   ? 45.783  76.759  44.202  1.00 26.33  ? 415 HOH A O   1 
HETATM 11997 O  O   . HOH S 3 .   ? 40.062  62.372  43.935  1.00 37.04  ? 416 HOH A O   1 
HETATM 11998 O  O   . HOH S 3 .   ? 35.136  58.934  57.722  1.00 42.40  ? 417 HOH A O   1 
HETATM 11999 O  O   . HOH S 3 .   ? 37.919  68.631  69.901  1.00 33.06  ? 418 HOH A O   1 
HETATM 12000 O  O   . HOH S 3 .   ? 55.728  75.836  44.497  1.00 25.56  ? 419 HOH A O   1 
HETATM 12001 O  O   . HOH S 3 .   ? 48.606  58.886  49.234  1.00 38.51  ? 420 HOH A O   1 
HETATM 12002 O  O   . HOH S 3 .   ? 42.853  71.240  62.428  1.00 23.45  ? 421 HOH A O   1 
HETATM 12003 O  O   . HOH S 3 .   ? 53.491  83.209  58.320  1.00 26.54  ? 422 HOH A O   1 
HETATM 12004 O  O   . HOH S 3 .   ? 45.274  87.093  60.143  1.00 18.05  ? 423 HOH A O   1 
HETATM 12005 O  O   . HOH S 3 .   ? 38.148  91.775  68.884  1.00 41.62  ? 424 HOH A O   1 
HETATM 12006 O  O   . HOH S 3 .   ? 51.208  58.625  67.101  1.00 39.14  ? 425 HOH A O   1 
HETATM 12007 O  O   . HOH S 3 .   ? 55.288  73.869  74.202  1.00 30.76  ? 426 HOH A O   1 
HETATM 12008 O  O   . HOH S 3 .   ? 51.706  80.876  68.340  1.00 26.59  ? 427 HOH A O   1 
HETATM 12009 O  O   . HOH S 3 .   ? 35.720  85.519  46.962  1.00 30.76  ? 428 HOH A O   1 
HETATM 12010 O  O   . HOH S 3 .   ? 50.461  89.827  56.300  1.00 25.43  ? 429 HOH A O   1 
HETATM 12011 O  O   . HOH S 3 .   ? 34.749  78.652  43.958  1.00 28.04  ? 430 HOH A O   1 
HETATM 12012 O  O   . HOH S 3 .   ? 46.107  79.002  42.527  1.00 28.24  ? 431 HOH A O   1 
HETATM 12013 O  O   . HOH S 3 .   ? 51.104  79.093  77.682  1.00 30.41  ? 432 HOH A O   1 
HETATM 12014 O  O   . HOH S 3 .   ? 35.738  88.500  42.897  1.00 27.85  ? 433 HOH A O   1 
HETATM 12015 O  O   . HOH S 3 .   ? 36.324  82.135  40.149  1.00 37.57  ? 434 HOH A O   1 
HETATM 12016 O  O   . HOH S 3 .   ? 46.508  67.946  69.845  1.00 29.14  ? 435 HOH A O   1 
HETATM 12017 O  O   . HOH S 3 .   ? 54.544  92.797  64.103  1.00 31.10  ? 436 HOH A O   1 
HETATM 12018 O  O   . HOH S 3 .   ? 35.318  76.767  60.675  1.00 35.72  ? 437 HOH A O   1 
HETATM 12019 O  O   . HOH S 3 .   ? 50.618  71.376  68.922  1.00 21.85  ? 438 HOH A O   1 
HETATM 12020 O  O   . HOH S 3 .   ? 30.231  86.838  80.596  1.00 53.58  ? 439 HOH A O   1 
HETATM 12021 O  O   . HOH S 3 .   ? 67.152  79.513  61.992  1.00 33.69  ? 440 HOH A O   1 
HETATM 12022 O  O   . HOH S 3 .   ? 40.846  76.474  62.078  1.00 30.78  ? 441 HOH A O   1 
HETATM 12023 O  O   . HOH S 3 .   ? 41.632  63.825  80.862  1.00 46.93  ? 442 HOH A O   1 
HETATM 12024 O  O   . HOH S 3 .   ? 52.639  91.544  57.752  1.00 27.27  ? 443 HOH A O   1 
HETATM 12025 O  O   . HOH S 3 .   ? 64.260  75.188  55.715  1.00 29.47  ? 444 HOH A O   1 
HETATM 12026 O  O   . HOH S 3 .   ? 38.184  98.464  59.189  1.00 32.84  ? 445 HOH A O   1 
HETATM 12027 O  O   . HOH S 3 .   ? 47.298  85.192  61.026  1.00 17.25  ? 446 HOH A O   1 
HETATM 12028 O  O   . HOH S 3 .   ? 61.513  65.030  62.522  1.00 36.59  ? 447 HOH A O   1 
HETATM 12029 O  O   . HOH S 3 .   ? 63.426  82.370  55.420  1.00 32.69  ? 448 HOH A O   1 
HETATM 12030 O  O   . HOH S 3 .   ? 49.919  72.394  76.755  1.00 36.11  ? 449 HOH A O   1 
HETATM 12031 O  O   . HOH S 3 .   ? 59.559  85.961  76.124  1.00 27.30  ? 450 HOH A O   1 
HETATM 12032 O  O   . HOH S 3 .   ? 63.761  77.632  67.732  1.00 21.93  ? 451 HOH A O   1 
HETATM 12033 O  O   . HOH S 3 .   ? 30.534  89.444  60.127  1.00 41.88  ? 452 HOH A O   1 
HETATM 12034 O  O   . HOH S 3 .   ? 48.238  84.522  39.933  1.00 27.01  ? 453 HOH A O   1 
HETATM 12035 O  O   . HOH S 3 .   ? 36.998  98.197  61.566  1.00 33.54  ? 454 HOH A O   1 
HETATM 12036 O  O   . HOH S 3 .   ? 58.413  59.289  56.445  1.00 40.86  ? 455 HOH A O   1 
HETATM 12037 O  O   . HOH S 3 .   ? 48.011  59.522  67.778  1.00 36.21  ? 456 HOH A O   1 
HETATM 12038 O  O   . HOH S 3 .   ? 39.742  77.449  56.592  1.00 21.03  ? 457 HOH A O   1 
HETATM 12039 O  O   . HOH S 3 .   ? 51.632  58.087  55.011  1.00 30.07  ? 458 HOH A O   1 
HETATM 12040 O  O   . HOH S 3 .   ? 52.330  72.234  75.892  1.00 31.71  ? 459 HOH A O   1 
HETATM 12041 O  O   . HOH S 3 .   ? 42.318  93.322  58.585  1.00 20.53  ? 460 HOH A O   1 
HETATM 12042 O  O   . HOH S 3 .   ? 41.282  82.864  78.463  1.00 40.62  ? 461 HOH A O   1 
HETATM 12043 O  O   . HOH S 3 .   ? 55.205  59.126  64.710  1.00 37.44  ? 462 HOH A O   1 
HETATM 12044 O  O   . HOH S 3 .   ? 44.311  59.847  64.526  1.00 29.29  ? 463 HOH A O   1 
HETATM 12045 O  O   . HOH S 3 .   ? 54.699  61.602  71.137  1.00 36.93  ? 464 HOH A O   1 
HETATM 12046 O  O   . HOH S 3 .   ? 60.186  81.697  64.626  1.00 28.81  ? 465 HOH A O   1 
HETATM 12047 O  O   . HOH S 3 .   ? 43.229  59.582  46.000  1.00 44.52  ? 466 HOH A O   1 
HETATM 12048 O  O   . HOH S 3 .   ? 59.866  71.770  45.917  1.00 22.28  ? 467 HOH A O   1 
HETATM 12049 O  O   . HOH S 3 .   ? 30.159  83.763  63.947  1.00 44.71  ? 468 HOH A O   1 
HETATM 12050 O  O   . HOH S 3 .   ? 51.624  65.363  75.925  1.00 33.09  ? 469 HOH A O   1 
HETATM 12051 O  O   . HOH S 3 .   ? 53.672  87.135  62.935  1.00 22.66  ? 470 HOH A O   1 
HETATM 12052 O  O   . HOH S 3 .   ? 42.179  58.275  72.474  1.00 35.71  ? 471 HOH A O   1 
HETATM 12053 O  O   . HOH S 3 .   ? 45.184  62.179  66.028  1.00 29.45  ? 472 HOH A O   1 
HETATM 12054 O  O   . HOH S 3 .   ? 46.809  88.408  48.175  1.00 17.73  ? 473 HOH A O   1 
HETATM 12055 O  O   . HOH S 3 .   ? 61.075  81.489  69.285  1.00 27.44  ? 474 HOH A O   1 
HETATM 12056 O  O   . HOH S 3 .   ? 56.045  61.385  50.813  1.00 53.45  ? 475 HOH A O   1 
HETATM 12057 O  O   . HOH S 3 .   ? 44.546  73.113  39.618  1.00 44.92  ? 476 HOH A O   1 
HETATM 12058 O  O   . HOH S 3 .   ? 31.526  66.591  65.908  1.00 49.70  ? 477 HOH A O   1 
HETATM 12059 O  O   . HOH S 3 .   ? 55.800  86.096  61.541  1.00 23.08  ? 478 HOH A O   1 
HETATM 12060 O  O   . HOH S 3 .   ? 29.384  83.798  60.744  1.00 41.80  ? 479 HOH A O   1 
HETATM 12061 O  O   . HOH S 3 .   ? 65.685  71.890  56.897  1.00 25.25  ? 480 HOH A O   1 
HETATM 12062 O  O   . HOH S 3 .   ? 47.412  86.398  43.979  1.00 25.75  ? 481 HOH A O   1 
HETATM 12063 O  O   . HOH S 3 .   ? 61.022  78.523  74.651  1.00 28.06  ? 482 HOH A O   1 
HETATM 12064 O  O   . HOH S 3 .   ? 49.844  91.074  68.958  1.00 24.53  ? 483 HOH A O   1 
HETATM 12065 O  O   . HOH S 3 .   ? 40.785  75.077  59.830  1.00 30.42  ? 484 HOH A O   1 
HETATM 12066 O  O   . HOH S 3 .   ? 47.845  93.816  53.809  1.00 23.95  ? 485 HOH A O   1 
HETATM 12067 O  O   . HOH S 3 .   ? 31.671  63.363  45.243  1.00 43.99  ? 486 HOH A O   1 
HETATM 12068 O  O   . HOH S 3 .   ? 56.301  86.266  56.788  1.00 32.69  ? 487 HOH A O   1 
HETATM 12069 O  O   . HOH S 3 .   ? 35.247  93.094  42.320  1.00 41.11  ? 488 HOH A O   1 
HETATM 12070 O  O   . HOH S 3 .   ? 57.171  61.380  58.100  1.00 30.86  ? 489 HOH A O   1 
HETATM 12071 O  O   . HOH S 3 .   ? 59.950  67.023  64.783  1.00 32.24  ? 490 HOH A O   1 
HETATM 12072 O  O   . HOH S 3 .   ? 63.098  76.593  50.228  1.00 31.59  ? 491 HOH A O   1 
HETATM 12073 O  O   . HOH S 3 .   ? 58.469  83.862  77.497  1.00 30.03  ? 492 HOH A O   1 
HETATM 12074 O  O   . HOH S 3 .   ? 42.634  91.641  44.005  1.00 18.77  ? 493 HOH A O   1 
HETATM 12075 O  O   . HOH S 3 .   ? 62.969  71.249  54.247  1.00 30.48  ? 494 HOH A O   1 
HETATM 12076 O  O   . HOH S 3 .   ? 52.868  77.073  57.733  1.00 18.66  ? 495 HOH A O   1 
HETATM 12077 O  O   . HOH S 3 .   ? 56.342  90.371  63.203  1.00 53.73  ? 496 HOH A O   1 
HETATM 12078 O  O   . HOH S 3 .   ? 66.934  76.859  64.020  1.00 26.63  ? 497 HOH A O   1 
HETATM 12079 O  O   . HOH S 3 .   ? 33.059  83.139  49.956  1.00 30.30  ? 498 HOH A O   1 
HETATM 12080 O  O   . HOH S 3 .   ? 41.138  101.132 56.534  1.00 43.03  ? 499 HOH A O   1 
HETATM 12081 O  O   . HOH S 3 .   ? 31.310  88.960  79.770  1.00 51.31  ? 500 HOH A O   1 
HETATM 12082 O  O   . HOH S 3 .   ? 37.497  90.590  49.516  1.00 31.75  ? 501 HOH A O   1 
HETATM 12083 O  O   . HOH S 3 .   ? 40.236  77.160  39.322  1.00 35.41  ? 502 HOH A O   1 
HETATM 12084 O  O   . HOH S 3 .   ? 42.560  73.277  59.939  1.00 28.21  ? 503 HOH A O   1 
HETATM 12085 O  O   . HOH S 3 .   ? 41.090  90.096  62.687  1.00 34.34  ? 504 HOH A O   1 
HETATM 12086 O  O   . HOH S 3 .   ? 30.182  71.989  65.459  1.00 41.09  ? 505 HOH A O   1 
HETATM 12087 O  O   . HOH S 3 .   ? 55.795  69.265  47.666  1.00 28.66  ? 506 HOH A O   1 
HETATM 12088 O  O   . HOH S 3 .   ? 40.206  87.632  37.902  1.00 50.62  ? 507 HOH A O   1 
HETATM 12089 O  O   . HOH S 3 .   ? 43.260  94.093  50.204  1.00 27.51  ? 508 HOH A O   1 
HETATM 12090 O  O   . HOH S 3 .   ? 31.799  68.200  69.730  1.00 36.80  ? 509 HOH A O   1 
HETATM 12091 O  O   . HOH S 3 .   ? 60.134  67.387  73.709  1.00 50.07  ? 510 HOH A O   1 
HETATM 12092 O  O   . HOH S 3 .   ? 43.699  56.571  48.008  1.00 40.33  ? 511 HOH A O   1 
HETATM 12093 O  O   . HOH S 3 .   ? 62.871  66.145  58.725  1.00 31.02  ? 512 HOH A O   1 
HETATM 12094 O  O   . HOH S 3 .   ? 54.824  78.205  42.447  1.00 47.00  ? 513 HOH A O   1 
HETATM 12095 O  O   . HOH S 3 .   ? 58.119  80.387  77.513  1.00 42.25  ? 514 HOH A O   1 
HETATM 12096 O  O   . HOH S 3 .   ? 28.953  66.180  47.945  1.00 44.57  ? 515 HOH A O   1 
HETATM 12097 O  O   . HOH S 3 .   ? 40.055  82.147  39.854  1.00 39.68  ? 516 HOH A O   1 
HETATM 12098 O  O   . HOH S 3 .   ? 26.556  66.826  51.041  1.00 52.40  ? 517 HOH A O   1 
HETATM 12099 O  O   . HOH S 3 .   ? 33.018  64.428  62.875  1.00 39.94  ? 518 HOH A O   1 
HETATM 12100 O  O   . HOH S 3 .   ? 54.021  66.610  44.314  1.00 34.57  ? 519 HOH A O   1 
HETATM 12101 O  O   . HOH S 3 .   ? 44.184  56.559  58.118  1.00 37.80  ? 520 HOH A O   1 
HETATM 12102 O  O   . HOH S 3 .   ? 66.095  75.774  53.047  1.00 30.36  ? 521 HOH A O   1 
HETATM 12103 O  O   . HOH S 3 .   ? 55.491  93.189  61.416  1.00 43.00  ? 522 HOH A O   1 
HETATM 12104 O  O   . HOH S 3 .   ? 46.035  81.740  41.876  1.00 35.71  ? 523 HOH A O   1 
HETATM 12105 O  O   . HOH S 3 .   ? 38.215  53.829  62.000  1.00 33.31  ? 524 HOH A O   1 
HETATM 12106 O  O   . HOH S 3 .   ? 49.468  73.865  79.592  1.00 37.07  ? 525 HOH A O   1 
HETATM 12107 O  O   . HOH S 3 .   ? 47.724  86.350  72.460  1.00 34.32  ? 526 HOH A O   1 
HETATM 12108 O  O   . HOH S 3 .   ? 59.764  80.502  57.362  1.00 20.21  ? 527 HOH A O   1 
HETATM 12109 O  O   . HOH S 3 .   ? 36.807  64.512  74.494  1.00 48.78  ? 528 HOH A O   1 
HETATM 12110 O  O   . HOH S 3 .   ? 28.748  73.872  69.269  1.00 45.74  ? 529 HOH A O   1 
HETATM 12111 O  O   . HOH S 3 .   ? 33.665  80.577  84.326  1.00 51.38  ? 530 HOH A O   1 
HETATM 12112 O  O   . HOH S 3 .   ? 32.966  76.894  77.619  1.00 51.20  ? 531 HOH A O   1 
HETATM 12113 O  O   . HOH S 3 .   ? 34.337  92.687  54.011  1.00 47.52  ? 532 HOH A O   1 
HETATM 12114 O  O   . HOH S 3 .   ? 40.042  95.264  51.981  1.00 40.60  ? 533 HOH A O   1 
HETATM 12115 O  O   . HOH S 3 .   ? 41.533  72.031  39.429  1.00 44.27  ? 534 HOH A O   1 
HETATM 12116 O  O   . HOH S 3 .   ? 38.586  96.530  54.759  1.00 42.42  ? 535 HOH A O   1 
HETATM 12117 O  O   . HOH S 3 .   ? 52.763  88.804  51.520  1.00 30.32  ? 536 HOH A O   1 
HETATM 12118 O  O   . HOH S 3 .   ? 31.020  63.421  53.916  1.00 54.03  ? 537 HOH A O   1 
HETATM 12119 O  O   . HOH S 3 .   ? 35.243  69.806  42.314  1.00 31.46  ? 538 HOH A O   1 
HETATM 12120 O  O   . HOH S 3 .   ? 61.051  74.810  48.677  1.00 29.56  ? 539 HOH A O   1 
HETATM 12121 O  O   . HOH S 3 .   ? 63.599  74.682  52.213  1.00 28.13  ? 540 HOH A O   1 
HETATM 12122 O  O   . HOH S 3 .   ? 55.840  90.220  58.704  1.00 38.74  ? 541 HOH A O   1 
HETATM 12123 O  O   . HOH S 3 .   ? 56.461  56.654  61.504  1.00 42.69  ? 542 HOH A O   1 
HETATM 12124 O  O   . HOH S 3 .   ? 50.746  85.102  47.918  1.00 34.79  ? 543 HOH A O   1 
HETATM 12125 O  O   . HOH S 3 .   ? 34.091  65.042  60.466  1.00 33.73  ? 544 HOH A O   1 
HETATM 12126 O  O   . HOH S 3 .   ? 51.369  57.703  50.198  1.00 47.81  ? 545 HOH A O   1 
HETATM 12127 O  O   . HOH S 3 .   ? 55.435  60.448  59.947  1.00 29.67  ? 546 HOH A O   1 
HETATM 12128 O  O   . HOH S 3 .   ? 31.032  88.536  55.273  1.00 50.63  ? 547 HOH A O   1 
HETATM 12129 O  O   . HOH S 3 .   ? 41.000  91.798  60.363  1.00 27.80  ? 548 HOH A O   1 
HETATM 12130 O  O   . HOH S 3 .   ? 58.054  56.316  59.391  1.00 58.53  ? 549 HOH A O   1 
HETATM 12131 O  O   . HOH S 3 .   ? 32.904  83.880  42.174  1.00 47.86  ? 550 HOH A O   1 
HETATM 12132 O  O   . HOH S 3 .   ? 48.428  51.487  56.382  1.00 40.94  ? 551 HOH A O   1 
HETATM 12133 O  O   . HOH S 3 .   ? 29.611  65.615  51.557  1.00 48.43  ? 552 HOH A O   1 
HETATM 12134 O  O   . HOH S 3 .   ? 42.163  60.859  42.885  1.00 40.41  ? 553 HOH A O   1 
HETATM 12135 O  O   . HOH S 3 .   ? 55.042  86.391  52.462  1.00 30.63  ? 554 HOH A O   1 
HETATM 12136 O  O   . HOH S 3 .   ? 41.634  87.934  62.368  1.00 29.59  ? 555 HOH A O   1 
HETATM 12137 O  O   . HOH S 3 .   ? 34.435  80.833  41.597  1.00 39.04  ? 556 HOH A O   1 
HETATM 12138 O  O   . HOH S 3 .   ? 45.545  58.552  45.611  1.00 46.21  ? 557 HOH A O   1 
HETATM 12139 O  O   . HOH S 3 .   ? 62.346  80.696  67.107  1.00 30.98  ? 558 HOH A O   1 
HETATM 12140 O  O   . HOH S 3 .   ? 30.230  69.054  67.111  1.00 40.56  ? 559 HOH A O   1 
HETATM 12141 O  O   . HOH S 3 .   ? 67.126  80.754  53.434  1.00 45.46  ? 560 HOH A O   1 
HETATM 12142 O  O   . HOH S 3 .   ? 58.420  86.418  55.173  1.00 33.29  ? 561 HOH A O   1 
HETATM 12143 O  O   . HOH S 3 .   ? 30.437  74.560  67.032  1.00 39.88  ? 562 HOH A O   1 
HETATM 12144 O  O   . HOH S 3 .   ? 30.764  66.282  63.378  1.00 45.46  ? 563 HOH A O   1 
HETATM 12145 O  O   . HOH S 3 .   ? 34.165  68.921  44.340  1.00 28.43  ? 564 HOH A O   1 
HETATM 12146 O  O   . HOH S 3 .   ? 46.214  58.039  65.786  1.00 34.74  ? 565 HOH A O   1 
HETATM 12147 O  O   . HOH S 3 .   ? 33.553  67.498  42.402  1.00 38.26  ? 566 HOH A O   1 
HETATM 12148 O  O   . HOH S 3 .   ? 32.572  68.106  47.972  1.00 37.64  ? 567 HOH A O   1 
HETATM 12149 O  O   . HOH S 3 .   ? 56.121  95.835  60.356  1.00 55.19  ? 568 HOH A O   1 
HETATM 12150 O  O   . HOH S 3 .   ? 54.210  86.341  54.608  1.00 29.93  ? 569 HOH A O   1 
HETATM 12151 O  O   . HOH S 3 .   ? 38.280  93.251  48.063  1.00 42.04  ? 570 HOH A O   1 
HETATM 12152 O  O   . HOH S 3 .   ? 46.190  100.681 55.662  1.00 35.36  ? 571 HOH A O   1 
HETATM 12153 O  O   . HOH S 3 .   ? 36.531  93.071  51.802  1.00 47.10  ? 572 HOH A O   1 
HETATM 12154 O  O   . HOH S 3 .   ? 31.697  66.175  50.684  1.00 39.88  ? 573 HOH A O   1 
HETATM 12155 O  O   . HOH S 3 .   ? 32.988  65.654  48.424  1.00 39.48  ? 574 HOH A O   1 
HETATM 12156 O  O   . HOH S 3 .   ? 46.990  83.527  43.448  1.00 41.77  ? 575 HOH A O   1 
HETATM 12157 O  O   . HOH S 3 .   ? 56.302  88.021  59.005  1.00 33.86  ? 576 HOH A O   1 
HETATM 12158 O  O   . HOH S 3 .   ? 52.527  88.590  54.670  1.00 30.38  ? 577 HOH A O   1 
HETATM 12159 O  O   . HOH S 3 .   ? 55.036  87.074  65.425  1.00 23.55  ? 578 HOH A O   1 
HETATM 12160 O  O   . HOH S 3 .   ? 46.954  56.355  46.702  1.00 50.03  ? 579 HOH A O   1 
HETATM 12161 O  O   . HOH S 3 .   ? 30.978  63.173  51.719  1.00 39.02  ? 580 HOH A O   1 
HETATM 12162 O  O   . HOH S 3 .   ? 50.203  86.611  44.553  1.00 36.75  ? 581 HOH A O   1 
HETATM 12163 O  O   . HOH S 3 .   ? 30.409  83.222  43.975  1.00 37.67  ? 582 HOH A O   1 
HETATM 12164 O  O   . HOH S 3 .   ? 53.005  61.036  74.225  1.00 44.17  ? 583 HOH A O   1 
HETATM 12165 O  O   . HOH S 3 .   ? 23.461  84.356  69.568  1.00 54.06  ? 584 HOH A O   1 
HETATM 12166 O  O   . HOH S 3 .   ? 48.094  85.774  47.555  1.00 31.22  ? 585 HOH A O   1 
HETATM 12167 O  O   . HOH S 3 .   ? 52.435  62.706  76.030  1.00 40.19  ? 586 HOH A O   1 
HETATM 12168 O  O   . HOH T 3 .   ? 67.034  72.695  87.404  1.00 44.24  ? 401 HOH B O   1 
HETATM 12169 O  O   . HOH T 3 .   ? 98.192  94.546  91.546  1.00 44.24  ? 402 HOH B O   1 
HETATM 12170 O  O   . HOH T 3 .   ? 70.754  62.990  78.482  1.00 51.10  ? 403 HOH B O   1 
HETATM 12171 O  O   . HOH T 3 .   ? 97.980  88.789  86.877  1.00 47.40  ? 404 HOH B O   1 
HETATM 12172 O  O   . HOH T 3 .   ? 99.584  78.377  67.069  1.00 45.78  ? 405 HOH B O   1 
HETATM 12173 O  O   . HOH T 3 .   ? 76.375  85.268  94.477  1.00 36.73  ? 406 HOH B O   1 
HETATM 12174 O  O   . HOH T 3 .   ? 92.316  94.197  93.410  1.00 33.09  ? 407 HOH B O   1 
HETATM 12175 O  O   . HOH T 3 .   ? 80.211  93.681  84.110  1.00 21.86  ? 408 HOH B O   1 
HETATM 12176 O  O   . HOH T 3 .   ? 73.586  68.152  87.077  1.00 42.87  ? 409 HOH B O   1 
HETATM 12177 O  O   . HOH T 3 .   ? 70.434  95.186  76.643  1.00 40.79  ? 410 HOH B O   1 
HETATM 12178 O  O   . HOH T 3 .   ? 74.111  92.989  87.839  1.00 33.23  ? 411 HOH B O   1 
HETATM 12179 O  O   . HOH T 3 .   ? 98.899  76.695  71.141  1.00 36.39  ? 412 HOH B O   1 
HETATM 12180 O  O   . HOH T 3 .   ? 89.647  64.382  84.455  1.00 43.35  ? 413 HOH B O   1 
HETATM 12181 O  O   . HOH T 3 .   ? 79.902  70.526  85.299  1.00 33.16  ? 414 HOH B O   1 
HETATM 12182 O  O   . HOH T 3 .   ? 69.609  67.988  70.350  1.00 34.66  ? 415 HOH B O   1 
HETATM 12183 O  O   . HOH T 3 .   ? 86.718  88.576  94.251  1.00 37.44  ? 416 HOH B O   1 
HETATM 12184 O  O   . HOH T 3 .   ? 92.178  97.764  67.228  1.00 30.86  ? 417 HOH B O   1 
HETATM 12185 O  O   . HOH T 3 .   ? 97.045  70.378  78.190  1.00 43.73  ? 418 HOH B O   1 
HETATM 12186 O  O   . HOH T 3 .   ? 83.577  77.729  78.747  1.00 26.32  ? 419 HOH B O   1 
HETATM 12187 O  O   . HOH T 3 .   ? 63.369  82.376  81.781  1.00 37.57  ? 420 HOH B O   1 
HETATM 12188 O  O   . HOH T 3 .   ? 97.659  74.050  70.296  1.00 46.78  ? 421 HOH B O   1 
HETATM 12189 O  O   . HOH T 3 .   ? 85.878  76.354  75.097  1.00 32.86  ? 422 HOH B O   1 
HETATM 12190 O  O   . HOH T 3 .   ? 93.154  98.261  77.515  1.00 35.72  ? 423 HOH B O   1 
HETATM 12191 O  O   . HOH T 3 .   ? 65.360  70.705  65.072  1.00 28.32  ? 424 HOH B O   1 
HETATM 12192 O  O   . HOH T 3 .   ? 63.862  91.308  73.888  1.00 32.29  ? 425 HOH B O   1 
HETATM 12193 O  O   . HOH T 3 .   ? 73.734  64.058  72.220  1.00 39.40  ? 426 HOH B O   1 
HETATM 12194 O  O   . HOH T 3 .   ? 86.078  78.141  77.521  1.00 30.87  ? 427 HOH B O   1 
HETATM 12195 O  O   . HOH T 3 .   ? 80.427  97.440  90.259  1.00 40.11  ? 428 HOH B O   1 
HETATM 12196 O  O   . HOH T 3 .   ? 85.212  66.040  80.222  1.00 34.37  ? 429 HOH B O   1 
HETATM 12197 O  O   . HOH T 3 .   ? 93.385  75.560  90.302  1.00 33.74  ? 430 HOH B O   1 
HETATM 12198 O  O   . HOH T 3 .   ? 67.579  93.040  75.130  1.00 30.61  ? 431 HOH B O   1 
HETATM 12199 O  O   . HOH T 3 .   ? 74.063  71.109  75.399  1.00 32.75  ? 432 HOH B O   1 
HETATM 12200 O  O   . HOH T 3 .   ? 61.466  83.523  74.532  1.00 36.96  ? 433 HOH B O   1 
HETATM 12201 O  O   . HOH T 3 .   ? 85.948  71.723  87.389  1.00 35.65  ? 434 HOH B O   1 
HETATM 12202 O  O   . HOH T 3 .   ? 67.843  90.099  67.728  1.00 36.08  ? 435 HOH B O   1 
HETATM 12203 O  O   . HOH T 3 .   ? 77.415  70.031  86.110  1.00 36.03  ? 436 HOH B O   1 
HETATM 12204 O  O   . HOH T 3 .   ? 71.253  65.445  72.376  1.00 39.04  ? 437 HOH B O   1 
HETATM 12205 O  O   . HOH T 3 .   ? 76.857  68.269  79.327  1.00 35.93  ? 438 HOH B O   1 
HETATM 12206 O  O   . HOH T 3 .   ? 64.839  88.238  74.230  1.00 29.82  ? 439 HOH B O   1 
HETATM 12207 O  O   . HOH T 3 .   ? 85.097  82.274  65.549  1.00 22.01  ? 440 HOH B O   1 
HETATM 12208 O  O   . HOH T 3 .   ? 68.502  74.915  90.564  1.00 54.12  ? 441 HOH B O   1 
HETATM 12209 O  O   . HOH T 3 .   ? 101.035 81.312  76.722  1.00 45.75  ? 442 HOH B O   1 
HETATM 12210 O  O   . HOH T 3 .   ? 85.529  96.425  78.699  1.00 30.60  ? 443 HOH B O   1 
HETATM 12211 O  O   . HOH T 3 .   ? 77.101  82.594  56.848  1.00 28.21  ? 444 HOH B O   1 
HETATM 12212 O  O   . HOH T 3 .   ? 91.040  64.463  81.690  1.00 41.03  ? 445 HOH B O   1 
HETATM 12213 O  O   . HOH T 3 .   ? 82.556  75.120  79.592  1.00 27.90  ? 446 HOH B O   1 
HETATM 12214 O  O   . HOH T 3 .   ? 69.233  65.447  76.937  1.00 43.80  ? 447 HOH B O   1 
HETATM 12215 O  O   . HOH T 3 .   ? 87.947  93.884  93.874  1.00 41.94  ? 448 HOH B O   1 
HETATM 12216 O  O   . HOH T 3 .   ? 75.726  74.993  66.932  1.00 25.52  ? 449 HOH B O   1 
HETATM 12217 O  O   . HOH T 3 .   ? 89.955  69.924  87.421  1.00 41.09  ? 450 HOH B O   1 
HETATM 12218 O  O   . HOH T 3 .   ? 77.732  69.762  88.967  1.00 42.97  ? 451 HOH B O   1 
HETATM 12219 O  O   . HOH T 3 .   ? 86.471  97.851  76.117  1.00 34.33  ? 452 HOH B O   1 
HETATM 12220 O  O   . HOH T 3 .   ? 94.230  90.035  95.820  1.00 33.41  ? 453 HOH B O   1 
HETATM 12221 O  O   . HOH T 3 .   ? 72.624  91.765  83.946  1.00 31.28  ? 454 HOH B O   1 
HETATM 12222 O  O   . HOH T 3 .   ? 76.766  85.055  68.019  1.00 24.95  ? 455 HOH B O   1 
HETATM 12223 O  O   . HOH T 3 .   ? 90.866  91.848  92.081  1.00 33.86  ? 456 HOH B O   1 
HETATM 12224 O  O   . HOH T 3 .   ? 76.834  81.874  62.589  1.00 25.06  ? 457 HOH B O   1 
HETATM 12225 O  O   . HOH T 3 .   ? 97.629  84.355  74.938  1.00 31.66  ? 458 HOH B O   1 
HETATM 12226 O  O   . HOH T 3 .   ? 84.874  94.301  80.021  1.00 28.78  ? 459 HOH B O   1 
HETATM 12227 O  O   . HOH T 3 .   ? 92.553  80.769  87.427  1.00 31.11  ? 460 HOH B O   1 
HETATM 12228 O  O   . HOH T 3 .   ? 74.253  65.669  65.491  1.00 38.54  ? 461 HOH B O   1 
HETATM 12229 O  O   . HOH T 3 .   ? 62.174  86.492  76.354  1.00 23.74  ? 462 HOH B O   1 
HETATM 12230 O  O   . HOH T 3 .   ? 96.489  91.269  73.076  1.00 32.93  ? 463 HOH B O   1 
HETATM 12231 O  O   . HOH T 3 .   ? 91.425  67.517  85.038  1.00 45.39  ? 464 HOH B O   1 
HETATM 12232 O  O   . HOH T 3 .   ? 72.508  59.616  66.845  1.00 54.69  ? 465 HOH B O   1 
HETATM 12233 O  O   . HOH T 3 .   ? 90.417  92.935  62.582  1.00 31.15  ? 466 HOH B O   1 
HETATM 12234 O  O   . HOH T 3 .   ? 82.463  81.655  66.228  1.00 20.97  ? 467 HOH B O   1 
HETATM 12235 O  O   . HOH T 3 .   ? 61.937  84.494  67.560  1.00 34.23  ? 468 HOH B O   1 
HETATM 12236 O  O   . HOH T 3 .   ? 74.775  83.959  63.693  1.00 22.45  ? 469 HOH B O   1 
HETATM 12237 O  O   . HOH T 3 .   ? 72.106  80.401  92.431  1.00 38.14  ? 470 HOH B O   1 
HETATM 12238 O  O   . HOH T 3 .   ? 88.323  81.258  76.528  1.00 26.21  ? 471 HOH B O   1 
HETATM 12239 O  O   . HOH T 3 .   ? 92.043  76.210  76.549  1.00 33.56  ? 472 HOH B O   1 
HETATM 12240 O  O   . HOH T 3 .   ? 91.674  73.793  59.097  1.00 41.35  ? 473 HOH B O   1 
HETATM 12241 O  O   . HOH T 3 .   ? 68.303  69.069  59.897  1.00 25.95  ? 474 HOH B O   1 
HETATM 12242 O  O   . HOH T 3 .   ? 91.932  77.398  89.905  1.00 33.52  ? 475 HOH B O   1 
HETATM 12243 O  O   . HOH T 3 .   ? 91.218  90.434  94.671  1.00 28.07  ? 476 HOH B O   1 
HETATM 12244 O  O   . HOH T 3 .   ? 69.732  94.695  81.578  1.00 20.03  ? 477 HOH B O   1 
HETATM 12245 O  O   . HOH T 3 .   ? 68.481  71.235  58.004  1.00 28.52  ? 478 HOH B O   1 
HETATM 12246 O  O   . HOH T 3 .   ? 66.710  76.022  88.515  1.00 44.87  ? 479 HOH B O   1 
HETATM 12247 O  O   . HOH T 3 .   ? 96.725  98.481  91.666  1.00 41.39  ? 480 HOH B O   1 
HETATM 12248 O  O   . HOH T 3 .   ? 93.326  98.174  92.714  1.00 36.82  ? 481 HOH B O   1 
HETATM 12249 O  O   . HOH T 3 .   ? 95.973  91.826  80.418  1.00 31.05  ? 482 HOH B O   1 
HETATM 12250 O  O   . HOH T 3 .   ? 89.969  84.653  60.857  1.00 26.32  ? 483 HOH B O   1 
HETATM 12251 O  O   . HOH T 3 .   ? 76.781  66.887  66.300  1.00 40.36  ? 484 HOH B O   1 
HETATM 12252 O  O   . HOH T 3 .   ? 68.522  80.834  65.853  1.00 26.76  ? 485 HOH B O   1 
HETATM 12253 O  O   . HOH T 3 .   ? 97.615  75.252  67.700  1.00 58.27  ? 486 HOH B O   1 
HETATM 12254 O  O   . HOH T 3 .   ? 89.550  79.681  62.609  1.00 29.97  ? 487 HOH B O   1 
HETATM 12255 O  O   . HOH T 3 .   ? 79.987  87.930  60.520  1.00 27.53  ? 488 HOH B O   1 
HETATM 12256 O  O   . HOH T 3 .   ? 80.386  71.705  61.135  1.00 40.45  ? 489 HOH B O   1 
HETATM 12257 O  O   . HOH T 3 .   ? 95.522  91.378  67.526  1.00 34.24  ? 490 HOH B O   1 
HETATM 12258 O  O   . HOH T 3 .   ? 68.187  77.965  88.129  1.00 37.42  ? 491 HOH B O   1 
HETATM 12259 O  O   . HOH T 3 .   ? 81.669  88.025  63.029  1.00 28.76  ? 492 HOH B O   1 
HETATM 12260 O  O   . HOH T 3 .   ? 64.920  76.239  79.487  1.00 37.27  ? 493 HOH B O   1 
HETATM 12261 O  O   . HOH T 3 .   ? 75.426  88.283  65.198  1.00 29.57  ? 494 HOH B O   1 
HETATM 12262 O  O   . HOH T 3 .   ? 78.496  99.496  80.459  1.00 42.92  ? 495 HOH B O   1 
HETATM 12263 O  O   . HOH T 3 .   ? 99.929  72.863  65.609  1.00 38.50  ? 496 HOH B O   1 
HETATM 12264 O  O   . HOH T 3 .   ? 99.323  92.747  75.978  1.00 48.15  ? 497 HOH B O   1 
HETATM 12265 O  O   . HOH T 3 .   ? 86.440  94.279  68.111  1.00 24.90  ? 498 HOH B O   1 
HETATM 12266 O  O   . HOH T 3 .   ? 75.565  83.521  73.933  1.00 19.85  ? 499 HOH B O   1 
HETATM 12267 O  O   . HOH T 3 .   ? 98.001  95.675  71.914  1.00 35.89  ? 500 HOH B O   1 
HETATM 12268 O  O   . HOH T 3 .   ? 78.245  75.011  94.328  1.00 42.05  ? 501 HOH B O   1 
HETATM 12269 O  O   . HOH T 3 .   ? 65.096  88.028  78.423  1.00 29.90  ? 502 HOH B O   1 
HETATM 12270 O  O   . HOH T 3 .   ? 95.319  84.153  56.614  1.00 37.49  ? 503 HOH B O   1 
HETATM 12271 O  O   . HOH T 3 .   ? 96.576  58.250  66.290  1.00 59.19  ? 504 HOH B O   1 
HETATM 12272 O  O   . HOH T 3 .   ? 79.737  89.924  58.487  1.00 31.92  ? 505 HOH B O   1 
HETATM 12273 O  O   . HOH T 3 .   ? 80.611  92.236  65.031  1.00 43.40  ? 506 HOH B O   1 
HETATM 12274 O  O   . HOH T 3 .   ? 88.173  79.629  64.821  1.00 26.81  ? 507 HOH B O   1 
HETATM 12275 O  O   . HOH T 3 .   ? 95.391  78.500  56.644  1.00 46.11  ? 508 HOH B O   1 
HETATM 12276 O  O   . HOH T 3 .   ? 85.860  90.880  60.880  1.00 29.77  ? 509 HOH B O   1 
HETATM 12277 O  O   . HOH T 3 .   ? 67.295  79.985  87.553  1.00 40.98  ? 510 HOH B O   1 
HETATM 12278 O  O   . HOH T 3 .   ? 85.395  101.311 73.960  1.00 30.22  ? 511 HOH B O   1 
HETATM 12279 O  O   . HOH T 3 .   ? 83.372  72.172  70.853  1.00 42.88  ? 512 HOH B O   1 
HETATM 12280 O  O   . HOH T 3 .   ? 96.544  96.293  78.551  1.00 37.60  ? 513 HOH B O   1 
HETATM 12281 O  O   . HOH T 3 .   ? 85.258  58.767  71.165  1.00 50.67  ? 514 HOH B O   1 
HETATM 12282 O  O   . HOH T 3 .   ? 93.783  88.857  54.648  1.00 48.22  ? 515 HOH B O   1 
HETATM 12283 O  O   . HOH T 3 .   ? 97.668  86.743  75.020  1.00 31.64  ? 516 HOH B O   1 
HETATM 12284 O  O   . HOH T 3 .   ? 74.970  96.672  78.992  1.00 25.24  ? 517 HOH B O   1 
HETATM 12285 O  O   . HOH T 3 .   ? 70.955  63.894  63.791  1.00 40.06  ? 518 HOH B O   1 
HETATM 12286 O  O   . HOH T 3 .   ? 77.272  85.550  57.157  1.00 40.85  ? 519 HOH B O   1 
HETATM 12287 O  O   . HOH T 3 .   ? 99.308  83.187  73.074  1.00 45.33  ? 520 HOH B O   1 
HETATM 12288 O  O   . HOH T 3 .   ? 72.905  76.451  98.326  1.00 42.22  ? 521 HOH B O   1 
HETATM 12289 O  O   . HOH T 3 .   ? 84.324  100.160 77.995  1.00 44.25  ? 522 HOH B O   1 
HETATM 12290 O  O   . HOH T 3 .   ? 69.130  65.788  74.042  1.00 42.35  ? 523 HOH B O   1 
HETATM 12291 O  O   . HOH T 3 .   ? 93.010  91.140  89.284  1.00 31.61  ? 524 HOH B O   1 
HETATM 12292 O  O   . HOH T 3 .   ? 89.719  72.481  87.551  1.00 39.71  ? 525 HOH B O   1 
HETATM 12293 O  O   . HOH T 3 .   ? 93.202  90.535  61.334  1.00 38.20  ? 526 HOH B O   1 
HETATM 12294 O  O   . HOH T 3 .   ? 69.198  59.577  79.665  1.00 54.45  ? 527 HOH B O   1 
HETATM 12295 O  O   . HOH T 3 .   ? 73.825  61.937  69.931  1.00 43.67  ? 528 HOH B O   1 
HETATM 12296 O  O   . HOH T 3 .   ? 70.065  86.871  69.374  1.00 26.31  ? 529 HOH B O   1 
HETATM 12297 O  O   . HOH T 3 .   ? 70.773  68.632  88.206  1.00 47.31  ? 530 HOH B O   1 
HETATM 12298 O  O   . HOH T 3 .   ? 65.929  90.960  76.086  1.00 29.17  ? 531 HOH B O   1 
HETATM 12299 O  O   . HOH T 3 .   ? 94.910  101.560 72.717  1.00 38.35  ? 532 HOH B O   1 
HETATM 12300 O  O   . HOH T 3 .   ? 71.815  59.752  70.886  1.00 50.22  ? 533 HOH B O   1 
HETATM 12301 O  O   . HOH T 3 .   ? 81.625  94.006  70.436  1.00 39.08  ? 534 HOH B O   1 
HETATM 12302 O  O   . HOH T 3 .   ? 86.040  97.480  71.028  1.00 26.25  ? 535 HOH B O   1 
HETATM 12303 O  O   . HOH T 3 .   ? 90.404  82.239  61.648  1.00 33.79  ? 536 HOH B O   1 
HETATM 12304 O  O   . HOH T 3 .   ? 101.139 81.888  68.437  1.00 55.54  ? 537 HOH B O   1 
HETATM 12305 O  O   . HOH T 3 .   ? 99.370  84.622  68.581  1.00 47.85  ? 538 HOH B O   1 
HETATM 12306 O  O   . HOH T 3 .   ? 88.825  87.601  96.683  1.00 42.61  ? 539 HOH B O   1 
HETATM 12307 O  O   . HOH T 3 .   ? 65.735  78.806  65.886  1.00 33.27  ? 540 HOH B O   1 
HETATM 12308 O  O   . HOH T 3 .   ? 87.989  72.953  93.374  1.00 47.28  ? 541 HOH B O   1 
HETATM 12309 O  O   . HOH T 3 .   ? 63.383  84.720  78.488  1.00 32.89  ? 542 HOH B O   1 
HETATM 12310 O  O   . HOH T 3 .   ? 68.954  93.911  77.704  1.00 30.38  ? 543 HOH B O   1 
HETATM 12311 O  O   . HOH T 3 .   ? 76.735  99.150  78.173  1.00 55.54  ? 544 HOH B O   1 
HETATM 12312 O  O   . HOH T 3 .   ? 96.046  80.006  91.017  1.00 36.73  ? 545 HOH B O   1 
HETATM 12313 O  O   . HOH T 3 .   ? 93.775  83.784  89.841  1.00 40.39  ? 546 HOH B O   1 
HETATM 12314 O  O   . HOH T 3 .   ? 74.095  85.516  94.543  1.00 40.24  ? 547 HOH B O   1 
HETATM 12315 O  O   . HOH T 3 .   ? 95.670  83.886  83.873  1.00 29.36  ? 548 HOH B O   1 
HETATM 12316 O  O   . HOH T 3 .   ? 93.054  88.000  89.199  1.00 35.99  ? 549 HOH B O   1 
HETATM 12317 O  O   . HOH T 3 .   ? 93.634  80.884  90.150  1.00 30.78  ? 550 HOH B O   1 
HETATM 12318 O  O   . HOH T 3 .   ? 101.693 76.978  67.899  1.00 45.01  ? 551 HOH B O   1 
HETATM 12319 O  O   . HOH T 3 .   ? 89.303  90.362  96.086  1.00 34.34  ? 552 HOH B O   1 
HETATM 12320 O  O   . HOH T 3 .   ? 93.978  83.886  93.382  1.00 51.42  ? 553 HOH B O   1 
HETATM 12321 O  O   . HOH T 3 .   ? 97.580  92.536  69.193  1.00 46.36  ? 554 HOH B O   1 
HETATM 12322 O  O   . HOH T 3 .   ? 70.498  61.119  75.157  1.00 58.54  ? 555 HOH B O   1 
HETATM 12323 O  O   . HOH T 3 .   ? 75.164  86.241  62.897  1.00 28.88  ? 556 HOH B O   1 
HETATM 12324 O  O   . HOH T 3 .   ? 88.837  90.665  54.315  1.00 43.70  ? 557 HOH B O   1 
HETATM 12325 O  O   . HOH T 3 .   ? 71.951  85.497  95.804  1.00 53.64  ? 558 HOH B O   1 
HETATM 12326 O  O   . HOH T 3 .   ? 66.695  64.563  77.032  1.00 47.68  ? 559 HOH B O   1 
HETATM 12327 O  O   . HOH T 3 .   ? 70.449  89.762  65.167  1.00 44.69  ? 560 HOH B O   1 
HETATM 12328 O  O   . HOH T 3 .   ? 97.731  87.154  64.346  1.00 43.17  ? 561 HOH B O   1 
HETATM 12329 O  O   . HOH T 3 .   ? 74.787  80.063  61.361  1.00 25.92  ? 562 HOH B O   1 
HETATM 12330 O  O   . HOH T 3 .   ? 98.532  97.169  74.052  1.00 46.39  ? 563 HOH B O   1 
HETATM 12331 O  O   . HOH T 3 .   ? 90.281  86.407  99.600  1.00 54.50  ? 564 HOH B O   1 
HETATM 12332 O  O   . HOH T 3 .   ? 91.840  90.003  99.663  1.00 37.60  ? 565 HOH B O   1 
HETATM 12333 O  O   . HOH T 3 .   ? 64.205  65.478  74.309  1.00 50.88  ? 566 HOH B O   1 
HETATM 12334 O  O   . HOH T 3 .   ? 63.113  66.854  76.509  1.00 50.35  ? 567 HOH B O   1 
HETATM 12335 O  O   . HOH T 3 .   ? 87.952  71.290  89.623  1.00 43.65  ? 568 HOH B O   1 
HETATM 12336 O  O   . HOH T 3 .   ? 92.693  70.148  87.128  1.00 53.60  ? 569 HOH B O   1 
HETATM 12337 O  O   . HOH T 3 .   ? 83.552  98.330  70.493  1.00 44.34  ? 570 HOH B O   1 
HETATM 12338 O  O   . HOH T 3 .   ? 81.895  95.847  72.849  1.00 38.25  ? 571 HOH B O   1 
HETATM 12339 O  O   . HOH T 3 .   ? 85.561  97.106  74.141  1.00 32.21  ? 572 HOH B O   1 
HETATM 12340 O  O   . HOH T 3 .   ? 70.099  61.952  72.989  1.00 53.91  ? 573 HOH B O   1 
HETATM 12341 O  O   . HOH T 3 .   ? 93.983  84.947  85.324  1.00 31.74  ? 574 HOH B O   1 
HETATM 12342 O  O   . HOH T 3 .   ? 99.813  80.605  73.856  1.00 45.72  ? 575 HOH B O   1 
HETATM 12343 O  O   . HOH T 3 .   ? 84.364  96.123  92.582  1.00 47.72  ? 576 HOH B O   1 
HETATM 12344 O  O   . HOH T 3 .   ? 67.437  65.095  72.697  1.00 50.49  ? 577 HOH B O   1 
HETATM 12345 O  O   . HOH T 3 .   ? 96.666  84.463  97.205  1.00 41.58  ? 578 HOH B O   1 
HETATM 12346 O  O   . HOH T 3 .   ? 99.032  79.858  90.307  1.00 47.37  ? 579 HOH B O   1 
HETATM 12347 O  O   . HOH T 3 .   ? 91.204  87.711  101.303 1.00 54.92  ? 580 HOH B O   1 
HETATM 12348 O  O   . HOH T 3 .   ? 89.804  72.728  91.235  1.00 44.91  ? 581 HOH B O   1 
HETATM 12349 O  O   . HOH T 3 .   ? 101.831 76.785  90.108  1.00 56.93  ? 582 HOH B O   1 
HETATM 12350 O  O   . HOH U 3 .   ? 56.961  111.844 39.169  1.00 35.70  ? 401 HOH C O   1 
HETATM 12351 O  O   . HOH U 3 .   ? 49.232  125.936 47.443  1.00 46.99  ? 402 HOH C O   1 
HETATM 12352 O  O   . HOH U 3 .   ? 48.295  99.113  56.684  1.00 34.97  ? 403 HOH C O   1 
HETATM 12353 O  O   . HOH U 3 .   ? 60.231  109.789 57.209  1.00 31.75  ? 404 HOH C O   1 
HETATM 12354 O  O   . HOH U 3 .   ? 39.418  114.381 41.646  1.00 36.99  ? 405 HOH C O   1 
HETATM 12355 O  O   . HOH U 3 .   ? 56.226  108.178 34.107  1.00 31.19  ? 406 HOH C O   1 
HETATM 12356 O  O   . HOH U 3 .   ? 72.554  111.975 35.095  1.00 47.46  ? 407 HOH C O   1 
HETATM 12357 O  O   . HOH U 3 .   ? 48.291  115.063 41.471  1.00 28.76  ? 408 HOH C O   1 
HETATM 12358 O  O   . HOH U 3 .   ? 67.635  87.917  29.957  1.00 33.92  ? 409 HOH C O   1 
HETATM 12359 O  O   . HOH U 3 .   ? 54.413  105.886 32.876  1.00 29.72  ? 410 HOH C O   1 
HETATM 12360 O  O   . HOH U 3 .   ? 47.072  90.048  35.189  1.00 21.66  ? 411 HOH C O   1 
HETATM 12361 O  O   . HOH U 3 .   ? 50.835  90.079  49.914  1.00 27.98  ? 412 HOH C O   1 
HETATM 12362 O  O   . HOH U 3 .   ? 45.489  124.379 32.723  1.00 39.10  ? 413 HOH C O   1 
HETATM 12363 O  O   . HOH U 3 .   ? 50.919  108.983 35.499  1.00 26.90  ? 414 HOH C O   1 
HETATM 12364 O  O   . HOH U 3 .   ? 62.161  111.204 57.618  1.00 32.86  ? 415 HOH C O   1 
HETATM 12365 O  O   . HOH U 3 .   ? 53.278  119.455 47.327  1.00 36.23  ? 416 HOH C O   1 
HETATM 12366 O  O   . HOH U 3 .   ? 63.151  94.463  24.167  1.00 30.10  ? 417 HOH C O   1 
HETATM 12367 O  O   . HOH U 3 .   ? 45.690  114.583 26.179  1.00 37.84  ? 418 HOH C O   1 
HETATM 12368 O  O   . HOH U 3 .   ? 47.495  103.797 23.188  1.00 38.05  ? 419 HOH C O   1 
HETATM 12369 O  O   . HOH U 3 .   ? 40.985  115.887 45.177  1.00 40.02  ? 420 HOH C O   1 
HETATM 12370 O  O   . HOH U 3 .   ? 41.446  89.731  39.200  1.00 28.03  ? 421 HOH C O   1 
HETATM 12371 O  O   . HOH U 3 .   ? 59.365  83.624  33.255  1.00 35.98  ? 422 HOH C O   1 
HETATM 12372 O  O   . HOH U 3 .   ? 44.522  91.449  42.221  1.00 20.21  ? 423 HOH C O   1 
HETATM 12373 O  O   . HOH U 3 .   ? 35.923  97.243  35.055  1.00 41.16  ? 424 HOH C O   1 
HETATM 12374 O  O   . HOH U 3 .   ? 57.617  108.755 27.780  1.00 37.06  ? 425 HOH C O   1 
HETATM 12375 O  O   . HOH U 3 .   ? 53.767  115.163 51.438  1.00 30.84  ? 426 HOH C O   1 
HETATM 12376 O  O   . HOH U 3 .   ? 57.535  112.619 57.247  1.00 32.63  ? 427 HOH C O   1 
HETATM 12377 O  O   . HOH U 3 .   ? 44.554  111.973 29.749  1.00 34.34  ? 428 HOH C O   1 
HETATM 12378 O  O   . HOH U 3 .   ? 65.084  102.472 46.781  1.00 28.18  ? 429 HOH C O   1 
HETATM 12379 O  O   . HOH U 3 .   ? 50.966  112.341 45.216  1.00 25.24  ? 430 HOH C O   1 
HETATM 12380 O  O   . HOH U 3 .   ? 47.647  117.419 49.478  1.00 33.60  ? 431 HOH C O   1 
HETATM 12381 O  O   . HOH U 3 .   ? 77.577  101.683 31.637  1.00 35.15  ? 432 HOH C O   1 
HETATM 12382 O  O   . HOH U 3 .   ? 65.444  102.772 38.164  1.00 19.49  ? 433 HOH C O   1 
HETATM 12383 O  O   . HOH U 3 .   ? 50.771  120.216 27.564  1.00 37.60  ? 434 HOH C O   1 
HETATM 12384 O  O   . HOH U 3 .   ? 38.369  101.843 46.517  1.00 32.32  ? 435 HOH C O   1 
HETATM 12385 O  O   . HOH U 3 .   ? 37.986  108.342 50.586  1.00 42.96  ? 436 HOH C O   1 
HETATM 12386 O  O   . HOH U 3 .   ? 34.980  110.011 40.193  1.00 40.56  ? 437 HOH C O   1 
HETATM 12387 O  O   . HOH U 3 .   ? 50.100  84.214  37.558  1.00 39.97  ? 438 HOH C O   1 
HETATM 12388 O  O   . HOH U 3 .   ? 48.134  96.177  18.138  1.00 38.99  ? 439 HOH C O   1 
HETATM 12389 O  O   . HOH U 3 .   ? 50.224  94.636  53.174  1.00 27.15  ? 440 HOH C O   1 
HETATM 12390 O  O   . HOH U 3 .   ? 53.078  101.195 58.829  1.00 24.58  ? 441 HOH C O   1 
HETATM 12391 O  O   . HOH U 3 .   ? 42.204  104.213 52.428  1.00 39.10  ? 442 HOH C O   1 
HETATM 12392 O  O   . HOH U 3 .   ? 52.835  90.165  32.252  1.00 21.27  ? 443 HOH C O   1 
HETATM 12393 O  O   . HOH U 3 .   ? 63.298  100.665 48.310  1.00 25.02  ? 444 HOH C O   1 
HETATM 12394 O  O   . HOH U 3 .   ? 60.270  99.204  44.661  1.00 25.61  ? 445 HOH C O   1 
HETATM 12395 O  O   . HOH U 3 .   ? 70.552  102.319 48.731  1.00 26.31  ? 446 HOH C O   1 
HETATM 12396 O  O   . HOH U 3 .   ? 35.356  102.116 40.249  1.00 30.54  ? 447 HOH C O   1 
HETATM 12397 O  O   . HOH U 3 .   ? 56.380  103.536 31.014  1.00 26.32  ? 448 HOH C O   1 
HETATM 12398 O  O   . HOH U 3 .   ? 59.939  118.287 48.852  1.00 32.87  ? 449 HOH C O   1 
HETATM 12399 O  O   . HOH U 3 .   ? 70.578  94.651  38.755  1.00 28.23  ? 450 HOH C O   1 
HETATM 12400 O  O   . HOH U 3 .   ? 60.226  124.319 30.740  1.00 52.98  ? 451 HOH C O   1 
HETATM 12401 O  O   . HOH U 3 .   ? 50.406  87.135  41.592  1.00 28.33  ? 452 HOH C O   1 
HETATM 12402 O  O   . HOH U 3 .   ? 64.597  109.050 23.270  1.00 46.42  ? 453 HOH C O   1 
HETATM 12403 O  O   . HOH U 3 .   ? 66.804  105.701 35.628  1.00 28.87  ? 454 HOH C O   1 
HETATM 12404 O  O   . HOH U 3 .   ? 63.550  103.211 40.118  1.00 19.76  ? 455 HOH C O   1 
HETATM 12405 O  O   . HOH U 3 .   ? 56.041  92.893  21.888  1.00 31.19  ? 456 HOH C O   1 
HETATM 12406 O  O   . HOH U 3 .   ? 64.461  90.886  35.211  1.00 24.47  ? 457 HOH C O   1 
HETATM 12407 O  O   . HOH U 3 .   ? 57.423  93.558  52.939  1.00 36.30  ? 458 HOH C O   1 
HETATM 12408 O  O   . HOH U 3 .   ? 53.895  94.014  56.549  1.00 28.37  ? 459 HOH C O   1 
HETATM 12409 O  O   . HOH U 3 .   ? 54.483  87.895  32.043  1.00 29.76  ? 460 HOH C O   1 
HETATM 12410 O  O   . HOH U 3 .   ? 60.100  109.330 46.582  1.00 24.13  ? 461 HOH C O   1 
HETATM 12411 O  O   . HOH U 3 .   ? 75.208  114.566 34.345  1.00 52.10  ? 462 HOH C O   1 
HETATM 12412 O  O   . HOH U 3 .   ? 70.898  92.788  33.350  1.00 39.06  ? 463 HOH C O   1 
HETATM 12413 O  O   . HOH U 3 .   ? 34.488  114.065 29.860  1.00 39.85  ? 464 HOH C O   1 
HETATM 12414 O  O   . HOH U 3 .   ? 63.937  124.431 39.137  1.00 50.67  ? 465 HOH C O   1 
HETATM 12415 O  O   . HOH U 3 .   ? 36.417  96.126  29.545  1.00 44.65  ? 466 HOH C O   1 
HETATM 12416 O  O   . HOH U 3 .   ? 42.508  113.283 38.111  1.00 27.95  ? 467 HOH C O   1 
HETATM 12417 O  O   . HOH U 3 .   ? 72.689  95.658  31.547  1.00 33.02  ? 468 HOH C O   1 
HETATM 12418 O  O   . HOH U 3 .   ? 38.104  104.670 45.293  1.00 31.19  ? 469 HOH C O   1 
HETATM 12419 O  O   . HOH U 3 .   ? 50.254  118.118 33.706  1.00 36.60  ? 470 HOH C O   1 
HETATM 12420 O  O   . HOH U 3 .   ? 43.831  112.722 36.433  1.00 28.44  ? 471 HOH C O   1 
HETATM 12421 O  O   . HOH U 3 .   ? 50.445  91.636  54.125  1.00 26.52  ? 472 HOH C O   1 
HETATM 12422 O  O   . HOH U 3 .   ? 39.167  101.927 20.452  1.00 45.32  ? 473 HOH C O   1 
HETATM 12423 O  O   . HOH U 3 .   ? 65.143  112.896 56.900  1.00 29.66  ? 474 HOH C O   1 
HETATM 12424 O  O   . HOH U 3 .   ? 52.738  113.052 53.339  1.00 31.81  ? 475 HOH C O   1 
HETATM 12425 O  O   . HOH U 3 .   ? 44.923  129.061 44.735  1.00 42.86  ? 476 HOH C O   1 
HETATM 12426 O  O   . HOH U 3 .   ? 67.293  110.655 26.069  1.00 44.27  ? 477 HOH C O   1 
HETATM 12427 O  O   . HOH U 3 .   ? 55.289  121.834 47.910  1.00 38.35  ? 478 HOH C O   1 
HETATM 12428 O  O   . HOH U 3 .   ? 35.246  107.603 44.406  1.00 38.11  ? 479 HOH C O   1 
HETATM 12429 O  O   . HOH U 3 .   ? 47.567  123.592 34.347  1.00 41.05  ? 480 HOH C O   1 
HETATM 12430 O  O   . HOH U 3 .   ? 61.911  87.266  34.098  1.00 24.89  ? 481 HOH C O   1 
HETATM 12431 O  O   . HOH U 3 .   ? 77.673  104.325 31.779  1.00 36.75  ? 482 HOH C O   1 
HETATM 12432 O  O   . HOH U 3 .   ? 68.260  94.561  27.149  1.00 37.81  ? 483 HOH C O   1 
HETATM 12433 O  O   . HOH U 3 .   ? 46.521  94.848  51.392  1.00 26.10  ? 484 HOH C O   1 
HETATM 12434 O  O   . HOH U 3 .   ? 54.131  100.152 43.780  1.00 18.68  ? 485 HOH C O   1 
HETATM 12435 O  O   . HOH U 3 .   ? 70.572  95.144  45.233  1.00 30.35  ? 486 HOH C O   1 
HETATM 12436 O  O   . HOH U 3 .   ? 41.176  114.829 49.240  1.00 35.99  ? 487 HOH C O   1 
HETATM 12437 O  O   . HOH U 3 .   ? 44.406  106.222 51.818  1.00 34.03  ? 488 HOH C O   1 
HETATM 12438 O  O   . HOH U 3 .   ? 63.258  114.893 56.655  1.00 28.26  ? 489 HOH C O   1 
HETATM 12439 O  O   . HOH U 3 .   ? 66.723  96.791  42.019  1.00 28.84  ? 490 HOH C O   1 
HETATM 12440 O  O   . HOH U 3 .   ? 65.054  107.234 35.287  1.00 37.53  ? 491 HOH C O   1 
HETATM 12441 O  O   . HOH U 3 .   ? 46.507  86.029  16.985  1.00 46.33  ? 492 HOH C O   1 
HETATM 12442 O  O   . HOH U 3 .   ? 39.938  94.672  25.229  1.00 34.65  ? 493 HOH C O   1 
HETATM 12443 O  O   . HOH U 3 .   ? 45.701  88.154  45.539  1.00 21.77  ? 494 HOH C O   1 
HETATM 12444 O  O   . HOH U 3 .   ? 44.422  86.047  19.440  1.00 35.85  ? 495 HOH C O   1 
HETATM 12445 O  O   . HOH U 3 .   ? 65.405  122.120 40.368  1.00 47.41  ? 496 HOH C O   1 
HETATM 12446 O  O   . HOH U 3 .   ? 72.695  125.391 32.710  1.00 47.66  ? 497 HOH C O   1 
HETATM 12447 O  O   . HOH U 3 .   ? 57.750  86.956  25.330  1.00 35.89  ? 498 HOH C O   1 
HETATM 12448 O  O   . HOH U 3 .   ? 75.063  94.227  36.599  1.00 37.21  ? 499 HOH C O   1 
HETATM 12449 O  O   . HOH U 3 .   ? 79.302  97.717  33.876  1.00 45.43  ? 500 HOH C O   1 
HETATM 12450 O  O   . HOH U 3 .   ? 39.939  112.895 37.004  1.00 33.75  ? 501 HOH C O   1 
HETATM 12451 O  O   . HOH U 3 .   ? 35.454  107.696 34.138  1.00 35.07  ? 502 HOH C O   1 
HETATM 12452 O  O   . HOH U 3 .   ? 69.691  107.423 24.297  1.00 44.31  ? 503 HOH C O   1 
HETATM 12453 O  O   . HOH U 3 .   ? 55.147  98.580  58.973  1.00 33.03  ? 504 HOH C O   1 
HETATM 12454 O  O   . HOH U 3 .   ? 58.914  102.723 53.401  1.00 34.23  ? 505 HOH C O   1 
HETATM 12455 O  O   . HOH U 3 .   ? 61.522  98.973  22.797  1.00 49.81  ? 506 HOH C O   1 
HETATM 12456 O  O   . HOH U 3 .   ? 31.535  102.153 31.388  1.00 39.93  ? 507 HOH C O   1 
HETATM 12457 O  O   . HOH U 3 .   ? 60.689  128.426 39.289  1.00 45.74  ? 508 HOH C O   1 
HETATM 12458 O  O   . HOH U 3 .   ? 52.736  117.898 49.523  1.00 34.86  ? 509 HOH C O   1 
HETATM 12459 O  O   . HOH U 3 .   ? 47.236  109.507 18.529  1.00 45.73  ? 510 HOH C O   1 
HETATM 12460 O  O   . HOH U 3 .   ? 69.549  105.752 35.337  1.00 35.03  ? 511 HOH C O   1 
HETATM 12461 O  O   . HOH U 3 .   ? 68.361  97.011  44.136  1.00 33.26  ? 512 HOH C O   1 
HETATM 12462 O  O   . HOH U 3 .   ? 52.342  106.390 34.641  1.00 29.83  ? 513 HOH C O   1 
HETATM 12463 O  O   . HOH U 3 .   ? 42.112  100.038 52.444  1.00 34.12  ? 514 HOH C O   1 
HETATM 12464 O  O   . HOH U 3 .   ? 44.627  81.948  34.234  1.00 39.86  ? 515 HOH C O   1 
HETATM 12465 O  O   . HOH U 3 .   ? 76.231  103.138 27.126  1.00 48.70  ? 516 HOH C O   1 
HETATM 12466 O  O   . HOH U 3 .   ? 66.318  113.531 44.566  1.00 38.89  ? 517 HOH C O   1 
HETATM 12467 O  O   . HOH U 3 .   ? 30.045  105.686 37.268  1.00 40.50  ? 518 HOH C O   1 
HETATM 12468 O  O   . HOH U 3 .   ? 54.293  87.057  42.857  1.00 39.53  ? 519 HOH C O   1 
HETATM 12469 O  O   . HOH U 3 .   ? 53.175  87.810  24.992  1.00 35.25  ? 520 HOH C O   1 
HETATM 12470 O  O   . HOH U 3 .   ? 70.732  103.479 34.393  1.00 34.13  ? 521 HOH C O   1 
HETATM 12471 O  O   . HOH U 3 .   ? 47.095  96.188  55.002  1.00 23.71  ? 522 HOH C O   1 
HETATM 12472 O  O   . HOH U 3 .   ? 45.932  111.602 26.194  1.00 31.94  ? 523 HOH C O   1 
HETATM 12473 O  O   . HOH U 3 .   ? 38.089  113.859 43.853  1.00 46.77  ? 524 HOH C O   1 
HETATM 12474 O  O   . HOH U 3 .   ? 41.562  93.551  20.806  1.00 31.19  ? 525 HOH C O   1 
HETATM 12475 O  O   . HOH U 3 .   ? 77.943  117.460 34.727  1.00 57.92  ? 526 HOH C O   1 
HETATM 12476 O  O   . HOH U 3 .   ? 35.865  101.418 47.756  1.00 41.61  ? 527 HOH C O   1 
HETATM 12477 O  O   . HOH U 3 .   ? 59.837  119.639 52.964  1.00 42.83  ? 528 HOH C O   1 
HETATM 12478 O  O   . HOH U 3 .   ? 57.139  85.694  44.364  1.00 55.56  ? 529 HOH C O   1 
HETATM 12479 O  O   . HOH U 3 .   ? 60.303  90.732  38.672  1.00 37.96  ? 530 HOH C O   1 
HETATM 12480 O  O   . HOH U 3 .   ? 56.561  96.616  50.090  1.00 26.31  ? 531 HOH C O   1 
HETATM 12481 O  O   . HOH U 3 .   ? 64.812  92.080  41.979  1.00 39.14  ? 532 HOH C O   1 
HETATM 12482 O  O   . HOH U 3 .   ? 45.306  97.527  52.848  1.00 37.33  ? 533 HOH C O   1 
HETATM 12483 O  O   . HOH U 3 .   ? 50.531  116.920 51.028  1.00 49.90  ? 534 HOH C O   1 
HETATM 12484 O  O   . HOH U 3 .   ? 57.857  91.141  20.781  1.00 38.12  ? 535 HOH C O   1 
HETATM 12485 O  O   . HOH U 3 .   ? 77.830  107.395 31.961  1.00 41.84  ? 536 HOH C O   1 
HETATM 12486 O  O   . HOH U 3 .   ? 49.121  89.340  47.892  1.00 29.36  ? 537 HOH C O   1 
HETATM 12487 O  O   . HOH U 3 .   ? 68.493  110.509 23.134  1.00 57.03  ? 538 HOH C O   1 
HETATM 12488 O  O   . HOH U 3 .   ? 49.263  91.987  51.397  1.00 25.92  ? 539 HOH C O   1 
HETATM 12489 O  O   . HOH U 3 .   ? 76.781  113.287 37.791  1.00 47.98  ? 540 HOH C O   1 
HETATM 12490 O  O   . HOH U 3 .   ? 47.570  124.334 31.261  1.00 41.08  ? 541 HOH C O   1 
HETATM 12491 O  O   . HOH U 3 .   ? 58.752  90.539  52.229  1.00 44.12  ? 542 HOH C O   1 
HETATM 12492 O  O   . HOH U 3 .   ? 59.372  87.583  44.368  1.00 50.44  ? 543 HOH C O   1 
HETATM 12493 O  O   . HOH U 3 .   ? 40.819  83.065  37.242  1.00 57.68  ? 544 HOH C O   1 
HETATM 12494 O  O   . HOH U 3 .   ? 58.010  104.601 55.804  1.00 33.18  ? 545 HOH C O   1 
HETATM 12495 O  O   . HOH U 3 .   ? 42.678  100.295 18.778  1.00 39.05  ? 546 HOH C O   1 
HETATM 12496 O  O   . HOH U 3 .   ? 54.565  118.979 51.655  1.00 37.10  ? 547 HOH C O   1 
HETATM 12497 O  O   . HOH U 3 .   ? 43.543  98.230  19.239  1.00 41.67  ? 548 HOH C O   1 
HETATM 12498 O  O   . HOH U 3 .   ? 39.310  93.412  22.212  1.00 34.07  ? 549 HOH C O   1 
HETATM 12499 O  O   . HOH U 3 .   ? 36.797  105.944 46.791  1.00 39.12  ? 550 HOH C O   1 
HETATM 12500 O  O   . HOH U 3 .   ? 79.109  100.138 32.050  1.00 49.25  ? 551 HOH C O   1 
HETATM 12501 O  O   . HOH U 3 .   ? 47.782  102.005 15.742  1.00 44.94  ? 552 HOH C O   1 
HETATM 12502 O  O   . HOH U 3 .   ? 51.649  84.937  40.209  1.00 38.58  ? 553 HOH C O   1 
HETATM 12503 O  O   . HOH U 3 .   ? 43.464  112.570 27.477  1.00 40.54  ? 554 HOH C O   1 
HETATM 12504 O  O   . HOH U 3 .   ? 38.054  113.877 39.060  1.00 35.35  ? 555 HOH C O   1 
HETATM 12505 O  O   . HOH U 3 .   ? 46.930  123.260 28.479  1.00 44.37  ? 556 HOH C O   1 
HETATM 12506 O  O   . HOH U 3 .   ? 46.031  117.950 51.929  1.00 43.10  ? 557 HOH C O   1 
HETATM 12507 O  O   . HOH U 3 .   ? 56.811  120.234 51.494  1.00 38.22  ? 558 HOH C O   1 
HETATM 12508 O  O   . HOH U 3 .   ? 34.479  95.430  31.611  1.00 50.84  ? 559 HOH C O   1 
HETATM 12509 O  O   . HOH U 3 .   ? 58.966  87.406  33.197  1.00 30.34  ? 560 HOH C O   1 
HETATM 12510 O  O   . HOH U 3 .   ? 45.684  103.404 20.637  1.00 32.49  ? 561 HOH C O   1 
HETATM 12511 O  O   . HOH U 3 .   ? 64.746  94.844  43.140  1.00 35.47  ? 562 HOH C O   1 
HETATM 12512 O  O   . HOH U 3 .   ? 65.787  116.170 44.367  1.00 45.15  ? 563 HOH C O   1 
HETATM 12513 O  O   . HOH U 3 .   ? 64.433  97.860  48.143  1.00 26.72  ? 564 HOH C O   1 
HETATM 12514 O  O   . HOH U 3 .   ? 54.327  90.234  55.796  1.00 41.32  ? 565 HOH C O   1 
HETATM 12515 O  O   . HOH U 3 .   ? 39.388  117.368 46.857  1.00 48.19  ? 566 HOH C O   1 
HETATM 12516 O  O   . HOH U 3 .   ? 45.787  101.398 16.789  1.00 37.15  ? 567 HOH C O   1 
HETATM 12517 O  O   . HOH U 3 .   ? 43.963  116.240 52.648  1.00 48.07  ? 568 HOH C O   1 
HETATM 12518 O  O   . HOH U 3 .   ? 49.308  118.012 53.511  1.00 50.23  ? 569 HOH C O   1 
HETATM 12519 O  O   . HOH U 3 .   ? 65.182  104.244 49.161  1.00 26.51  ? 570 HOH C O   1 
HETATM 12520 O  O   . HOH U 3 .   ? 35.654  96.230  18.055  1.00 52.97  ? 571 HOH C O   1 
HETATM 12521 O  O   . HOH U 3 .   ? 41.062  87.346  28.411  1.00 52.84  ? 572 HOH C O   1 
HETATM 12522 O  O   . HOH U 3 .   ? 35.847  112.308 40.144  1.00 37.74  ? 573 HOH C O   1 
HETATM 12523 O  O   . HOH U 3 .   ? 44.012  92.361  22.033  1.00 27.66  ? 574 HOH C O   1 
HETATM 12524 O  O   . HOH U 3 .   ? 58.375  88.674  37.288  1.00 48.82  ? 575 HOH C O   1 
HETATM 12525 O  O   . HOH U 3 .   ? 61.885  90.457  36.741  1.00 43.60  ? 576 HOH C O   1 
HETATM 12526 O  O   . HOH U 3 .   ? 64.267  97.999  23.126  1.00 39.41  ? 577 HOH C O   1 
HETATM 12527 O  O   . HOH U 3 .   ? 67.364  101.785 21.132  1.00 45.60  ? 578 HOH C O   1 
HETATM 12528 O  O   . HOH U 3 .   ? 38.266  91.216  24.844  1.00 48.20  ? 579 HOH C O   1 
HETATM 12529 O  O   . HOH V 3 .   ? 98.523  100.047 44.345  1.00 52.31  ? 401 HOH D O   1 
HETATM 12530 O  O   . HOH V 3 .   ? 98.790  117.084 52.390  1.00 45.47  ? 402 HOH D O   1 
HETATM 12531 O  O   . HOH V 3 .   ? 78.107  95.659  42.401  1.00 43.85  ? 403 HOH D O   1 
HETATM 12532 O  O   . HOH V 3 .   ? 74.097  127.709 53.703  1.00 42.99  ? 404 HOH D O   1 
HETATM 12533 O  O   . HOH V 3 .   ? 99.002  99.006  64.001  1.00 40.55  ? 405 HOH D O   1 
HETATM 12534 O  O   . HOH V 3 .   ? 80.879  95.784  40.467  1.00 32.31  ? 406 HOH D O   1 
HETATM 12535 O  O   . HOH V 3 .   ? 95.395  103.495 39.224  1.00 43.61  ? 407 HOH D O   1 
HETATM 12536 O  O   . HOH V 3 .   ? 97.776  111.555 49.880  1.00 38.32  ? 408 HOH D O   1 
HETATM 12537 O  O   . HOH V 3 .   ? 89.168  107.005 70.896  1.00 28.11  ? 409 HOH D O   1 
HETATM 12538 O  O   . HOH V 3 .   ? 78.969  116.014 36.727  1.00 56.95  ? 410 HOH D O   1 
HETATM 12539 O  O   . HOH V 3 .   ? 65.047  122.373 53.118  1.00 37.29  ? 411 HOH D O   1 
HETATM 12540 O  O   . HOH V 3 .   ? 84.792  116.509 75.606  1.00 37.35  ? 412 HOH D O   1 
HETATM 12541 O  O   . HOH V 3 .   ? 94.699  121.452 62.130  1.00 40.24  ? 413 HOH D O   1 
HETATM 12542 O  O   . HOH V 3 .   ? 68.784  116.461 56.028  1.00 26.91  ? 414 HOH D O   1 
HETATM 12543 O  O   . HOH V 3 .   ? 70.509  116.187 70.257  1.00 29.11  ? 415 HOH D O   1 
HETATM 12544 O  O   . HOH V 3 .   ? 93.601  108.529 45.187  1.00 35.92  ? 416 HOH D O   1 
HETATM 12545 O  O   . HOH V 3 .   ? 82.565  110.906 72.281  1.00 32.56  ? 417 HOH D O   1 
HETATM 12546 O  O   . HOH V 3 .   ? 88.709  105.914 38.207  1.00 43.21  ? 418 HOH D O   1 
HETATM 12547 O  O   . HOH V 3 .   ? 102.413 102.419 60.105  1.00 38.87  ? 419 HOH D O   1 
HETATM 12548 O  O   . HOH V 3 .   ? 86.321  98.404  42.314  1.00 35.73  ? 420 HOH D O   1 
HETATM 12549 O  O   . HOH V 3 .   ? 89.511  105.296 33.628  1.00 53.84  ? 421 HOH D O   1 
HETATM 12550 O  O   . HOH V 3 .   ? 82.551  90.582  62.348  1.00 33.03  ? 422 HOH D O   1 
HETATM 12551 O  O   . HOH V 3 .   ? 73.439  104.338 52.049  1.00 28.32  ? 423 HOH D O   1 
HETATM 12552 O  O   . HOH V 3 .   ? 73.911  98.131  38.994  1.00 29.40  ? 424 HOH D O   1 
HETATM 12553 O  O   . HOH V 3 .   ? 102.093 105.578 66.298  1.00 40.85  ? 425 HOH D O   1 
HETATM 12554 O  O   . HOH V 3 .   ? 90.412  100.010 67.902  1.00 31.39  ? 426 HOH D O   1 
HETATM 12555 O  O   . HOH V 3 .   ? 77.588  104.173 56.424  1.00 27.76  ? 427 HOH D O   1 
HETATM 12556 O  O   . HOH V 3 .   ? 81.489  125.042 62.103  1.00 39.37  ? 428 HOH D O   1 
HETATM 12557 O  O   . HOH V 3 .   ? 84.202  122.166 70.836  1.00 28.44  ? 429 HOH D O   1 
HETATM 12558 O  O   . HOH V 3 .   ? 95.208  123.341 44.832  1.00 47.70  ? 430 HOH D O   1 
HETATM 12559 O  O   . HOH V 3 .   ? 84.901  116.908 57.944  1.00 34.21  ? 431 HOH D O   1 
HETATM 12560 O  O   . HOH V 3 .   ? 67.818  104.181 50.285  1.00 27.57  ? 432 HOH D O   1 
HETATM 12561 O  O   . HOH V 3 .   ? 86.889  90.399  58.376  1.00 28.61  ? 433 HOH D O   1 
HETATM 12562 O  O   . HOH V 3 .   ? 84.484  110.936 70.643  1.00 30.37  ? 434 HOH D O   1 
HETATM 12563 O  O   . HOH V 3 .   ? 93.627  101.337 70.444  1.00 38.66  ? 435 HOH D O   1 
HETATM 12564 O  O   . HOH V 3 .   ? 82.489  93.769  64.746  1.00 34.83  ? 436 HOH D O   1 
HETATM 12565 O  O   . HOH V 3 .   ? 77.276  116.476 51.226  1.00 37.23  ? 437 HOH D O   1 
HETATM 12566 O  O   . HOH V 3 .   ? 101.500 106.144 47.071  1.00 48.77  ? 438 HOH D O   1 
HETATM 12567 O  O   . HOH V 3 .   ? 82.043  105.612 37.555  1.00 38.09  ? 439 HOH D O   1 
HETATM 12568 O  O   . HOH V 3 .   ? 79.387  126.495 60.896  1.00 45.64  ? 440 HOH D O   1 
HETATM 12569 O  O   . HOH V 3 .   ? 89.709  105.081 45.976  1.00 35.01  ? 441 HOH D O   1 
HETATM 12570 O  O   . HOH V 3 .   ? 75.064  110.514 70.856  1.00 27.08  ? 442 HOH D O   1 
HETATM 12571 O  O   . HOH V 3 .   ? 67.410  103.670 53.372  1.00 33.01  ? 443 HOH D O   1 
HETATM 12572 O  O   . HOH V 3 .   ? 79.979  117.275 74.829  1.00 36.47  ? 444 HOH D O   1 
HETATM 12573 O  O   . HOH V 3 .   ? 72.446  120.820 65.370  1.00 29.63  ? 445 HOH D O   1 
HETATM 12574 O  O   . HOH V 3 .   ? 85.967  121.554 53.808  1.00 40.26  ? 446 HOH D O   1 
HETATM 12575 O  O   . HOH V 3 .   ? 82.099  89.839  51.178  1.00 25.04  ? 447 HOH D O   1 
HETATM 12576 O  O   . HOH V 3 .   ? 67.653  111.165 60.910  1.00 24.64  ? 448 HOH D O   1 
HETATM 12577 O  O   . HOH V 3 .   ? 70.210  108.529 45.828  1.00 23.52  ? 449 HOH D O   1 
HETATM 12578 O  O   . HOH V 3 .   ? 64.206  121.214 55.572  1.00 38.06  ? 450 HOH D O   1 
HETATM 12579 O  O   . HOH V 3 .   ? 85.824  123.015 33.817  1.00 50.47  ? 451 HOH D O   1 
HETATM 12580 O  O   . HOH V 3 .   ? 90.585  112.612 52.415  1.00 30.63  ? 452 HOH D O   1 
HETATM 12581 O  O   . HOH V 3 .   ? 99.899  99.141  55.185  1.00 40.96  ? 453 HOH D O   1 
HETATM 12582 O  O   . HOH V 3 .   ? 94.158  117.085 44.759  1.00 47.45  ? 454 HOH D O   1 
HETATM 12583 O  O   . HOH V 3 .   ? 79.976  105.325 46.588  1.00 29.45  ? 455 HOH D O   1 
HETATM 12584 O  O   . HOH V 3 .   ? 74.020  101.619 58.361  1.00 34.57  ? 456 HOH D O   1 
HETATM 12585 O  O   . HOH V 3 .   ? 72.209  117.152 51.875  1.00 33.54  ? 457 HOH D O   1 
HETATM 12586 O  O   . HOH V 3 .   ? 104.849 104.516 52.177  1.00 43.11  ? 458 HOH D O   1 
HETATM 12587 O  O   . HOH V 3 .   ? 86.721  100.675 40.566  1.00 35.64  ? 459 HOH D O   1 
HETATM 12588 O  O   . HOH V 3 .   ? 73.051  111.543 66.734  1.00 21.08  ? 460 HOH D O   1 
HETATM 12589 O  O   . HOH V 3 .   ? 76.374  110.307 53.787  1.00 22.70  ? 461 HOH D O   1 
HETATM 12590 O  O   . HOH V 3 .   ? 71.234  107.661 58.491  1.00 27.75  ? 462 HOH D O   1 
HETATM 12591 O  O   . HOH V 3 .   ? 88.941  113.131 54.625  1.00 32.80  ? 463 HOH D O   1 
HETATM 12592 O  O   . HOH V 3 .   ? 74.933  126.258 34.531  1.00 53.72  ? 464 HOH D O   1 
HETATM 12593 O  O   . HOH V 3 .   ? 101.999 109.654 49.958  1.00 42.56  ? 465 HOH D O   1 
HETATM 12594 O  O   . HOH V 3 .   ? 98.061  117.372 39.997  1.00 53.28  ? 466 HOH D O   1 
HETATM 12595 O  O   . HOH V 3 .   ? 77.290  122.286 67.806  1.00 36.82  ? 467 HOH D O   1 
HETATM 12596 O  O   . HOH V 3 .   ? 71.769  101.014 35.257  1.00 24.33  ? 468 HOH D O   1 
HETATM 12597 O  O   . HOH V 3 .   ? 83.582  103.631 57.247  1.00 23.48  ? 469 HOH D O   1 
HETATM 12598 O  O   . HOH V 3 .   ? 98.482  97.258  57.073  1.00 40.29  ? 470 HOH D O   1 
HETATM 12599 O  O   . HOH V 3 .   ? 82.075  123.142 72.492  1.00 43.16  ? 471 HOH D O   1 
HETATM 12600 O  O   . HOH V 3 .   ? 93.150  101.699 40.192  1.00 39.97  ? 472 HOH D O   1 
HETATM 12601 O  O   . HOH V 3 .   ? 76.178  98.786  37.569  1.00 30.73  ? 473 HOH D O   1 
HETATM 12602 O  O   . HOH V 3 .   ? 74.867  112.418 54.435  1.00 22.04  ? 474 HOH D O   1 
HETATM 12603 O  O   . HOH V 3 .   ? 74.199  102.023 53.414  1.00 26.35  ? 475 HOH D O   1 
HETATM 12604 O  O   . HOH V 3 .   ? 98.104  122.534 45.553  1.00 48.40  ? 476 HOH D O   1 
HETATM 12605 O  O   . HOH V 3 .   ? 90.387  113.937 75.223  1.00 46.47  ? 477 HOH D O   1 
HETATM 12606 O  O   . HOH V 3 .   ? 80.294  124.363 64.702  1.00 37.14  ? 478 HOH D O   1 
HETATM 12607 O  O   . HOH V 3 .   ? 99.383  109.316 48.953  1.00 36.47  ? 479 HOH D O   1 
HETATM 12608 O  O   . HOH V 3 .   ? 87.752  96.217  69.259  1.00 25.76  ? 480 HOH D O   1 
HETATM 12609 O  O   . HOH V 3 .   ? 98.062  120.436 54.364  1.00 42.31  ? 481 HOH D O   1 
HETATM 12610 O  O   . HOH V 3 .   ? 74.732  116.224 52.435  1.00 30.12  ? 482 HOH D O   1 
HETATM 12611 O  O   . HOH V 3 .   ? 84.132  100.850 70.746  1.00 29.43  ? 483 HOH D O   1 
HETATM 12612 O  O   . HOH V 3 .   ? 94.710  128.100 60.367  1.00 45.39  ? 484 HOH D O   1 
HETATM 12613 O  O   . HOH V 3 .   ? 103.529 100.192 53.333  1.00 42.85  ? 485 HOH D O   1 
HETATM 12614 O  O   . HOH V 3 .   ? 87.801  92.931  60.909  1.00 30.63  ? 486 HOH D O   1 
HETATM 12615 O  O   . HOH V 3 .   ? 105.035 109.471 57.038  1.00 44.66  ? 487 HOH D O   1 
HETATM 12616 O  O   . HOH V 3 .   ? 80.523  98.594  37.906  1.00 44.44  ? 488 HOH D O   1 
HETATM 12617 O  O   . HOH V 3 .   ? 87.278  115.200 55.015  1.00 33.27  ? 489 HOH D O   1 
HETATM 12618 O  O   . HOH V 3 .   ? 88.286  102.939 38.975  1.00 44.34  ? 490 HOH D O   1 
HETATM 12619 O  O   . HOH V 3 .   ? 107.460 97.068  59.544  1.00 53.60  ? 491 HOH D O   1 
HETATM 12620 O  O   . HOH V 3 .   ? 61.192  118.561 57.961  1.00 41.27  ? 492 HOH D O   1 
HETATM 12621 O  O   . HOH V 3 .   ? 113.378 108.890 56.108  1.00 49.19  ? 493 HOH D O   1 
HETATM 12622 O  O   . HOH V 3 .   ? 109.007 104.616 58.378  1.00 49.78  ? 494 HOH D O   1 
HETATM 12623 O  O   . HOH V 3 .   ? 71.232  123.746 45.961  1.00 47.24  ? 495 HOH D O   1 
HETATM 12624 O  O   . HOH V 3 .   ? 79.991  100.866 69.730  1.00 43.15  ? 496 HOH D O   1 
HETATM 12625 O  O   . HOH V 3 .   ? 76.929  94.188  59.501  1.00 42.44  ? 497 HOH D O   1 
HETATM 12626 O  O   . HOH V 3 .   ? 80.982  98.470  68.544  1.00 41.33  ? 498 HOH D O   1 
HETATM 12627 O  O   . HOH V 3 .   ? 77.370  126.422 51.278  1.00 42.68  ? 499 HOH D O   1 
HETATM 12628 O  O   . HOH V 3 .   ? 82.429  107.507 39.681  1.00 39.74  ? 500 HOH D O   1 
HETATM 12629 O  O   . HOH V 3 .   ? 88.296  112.075 75.453  1.00 39.50  ? 501 HOH D O   1 
HETATM 12630 O  O   . HOH V 3 .   ? 67.750  115.519 64.594  1.00 46.86  ? 502 HOH D O   1 
HETATM 12631 O  O   . HOH V 3 .   ? 93.458  92.157  56.439  1.00 37.81  ? 503 HOH D O   1 
HETATM 12632 O  O   . HOH V 3 .   ? 80.755  121.644 74.285  1.00 41.98  ? 504 HOH D O   1 
HETATM 12633 O  O   . HOH V 3 .   ? 94.401  126.033 41.641  1.00 45.00  ? 505 HOH D O   1 
HETATM 12634 O  O   . HOH V 3 .   ? 75.672  110.061 42.084  1.00 50.25  ? 506 HOH D O   1 
HETATM 12635 O  O   . HOH V 3 .   ? 73.860  102.858 62.561  1.00 38.23  ? 507 HOH D O   1 
HETATM 12636 O  O   . HOH V 3 .   ? 76.449  109.384 75.012  1.00 34.40  ? 508 HOH D O   1 
HETATM 12637 O  O   . HOH V 3 .   ? 70.070  102.566 56.179  1.00 46.46  ? 509 HOH D O   1 
HETATM 12638 O  O   . HOH V 3 .   ? 69.274  106.033 57.339  1.00 25.96  ? 510 HOH D O   1 
HETATM 12639 O  O   . HOH V 3 .   ? 73.550  95.666  61.751  1.00 51.54  ? 511 HOH D O   1 
HETATM 12640 O  O   . HOH V 3 .   ? 79.477  124.999 71.616  1.00 50.71  ? 512 HOH D O   1 
HETATM 12641 O  O   . HOH V 3 .   ? 67.142  118.540 62.450  1.00 37.00  ? 513 HOH D O   1 
HETATM 12642 O  O   . HOH V 3 .   ? 70.471  92.597  64.645  1.00 43.19  ? 514 HOH D O   1 
HETATM 12643 O  O   . HOH V 3 .   ? 78.656  113.342 40.078  1.00 45.53  ? 515 HOH D O   1 
HETATM 12644 O  O   . HOH V 3 .   ? 83.318  113.177 46.507  1.00 39.82  ? 516 HOH D O   1 
HETATM 12645 O  O   . HOH V 3 .   ? 70.720  117.371 53.825  1.00 32.06  ? 517 HOH D O   1 
HETATM 12646 O  O   . HOH V 3 .   ? 71.738  105.651 62.899  1.00 32.01  ? 518 HOH D O   1 
HETATM 12647 O  O   . HOH V 3 .   ? 69.265  101.660 53.315  1.00 38.58  ? 519 HOH D O   1 
HETATM 12648 O  O   . HOH V 3 .   ? 87.594  106.218 36.029  1.00 49.29  ? 520 HOH D O   1 
HETATM 12649 O  O   . HOH V 3 .   ? 77.710  116.343 75.630  1.00 45.93  ? 521 HOH D O   1 
HETATM 12650 O  O   . HOH V 3 .   ? 94.129  121.814 67.113  1.00 44.47  ? 522 HOH D O   1 
HETATM 12651 O  O   . HOH V 3 .   ? 100.327 123.898 59.977  1.00 40.46  ? 523 HOH D O   1 
HETATM 12652 O  O   . HOH V 3 .   ? 89.193  91.873  57.852  1.00 36.60  ? 524 HOH D O   1 
HETATM 12653 O  O   . HOH V 3 .   ? 97.262  123.152 63.437  1.00 38.93  ? 525 HOH D O   1 
HETATM 12654 O  O   . HOH V 3 .   ? 93.093  120.574 72.059  1.00 36.11  ? 526 HOH D O   1 
HETATM 12655 O  O   . HOH V 3 .   ? 84.336  95.652  66.653  1.00 32.40  ? 527 HOH D O   1 
HETATM 12656 O  O   . HOH V 3 .   ? 99.653  124.110 62.699  1.00 38.20  ? 528 HOH D O   1 
HETATM 12657 O  O   . HOH V 3 .   ? 95.219  121.563 72.168  1.00 54.03  ? 529 HOH D O   1 
HETATM 12658 O  O   . HOH V 3 .   ? 64.309  103.095 54.677  1.00 47.57  ? 530 HOH D O   1 
HETATM 12659 O  O   . HOH V 3 .   ? 96.939  89.215  63.961  1.00 57.14  ? 531 HOH D O   1 
HETATM 12660 O  O   . HOH V 3 .   ? 86.793  102.400 36.819  1.00 41.43  ? 532 HOH D O   1 
HETATM 12661 O  O   . HOH V 3 .   ? 72.007  103.519 64.000  1.00 46.32  ? 533 HOH D O   1 
HETATM 12662 O  O   . HOH V 3 .   ? 84.914  106.945 35.000  1.00 54.37  ? 534 HOH D O   1 
HETATM 12663 O  O   . HOH V 3 .   ? 61.338  113.537 58.726  1.00 53.75  ? 535 HOH D O   1 
HETATM 12664 O  O   . HOH V 3 .   ? 74.192  103.910 59.997  1.00 33.49  ? 536 HOH D O   1 
HETATM 12665 O  O   . HOH V 3 .   ? 94.197  121.278 69.905  1.00 41.50  ? 537 HOH D O   1 
HETATM 12666 O  O   . HOH V 3 .   ? 90.236  123.745 64.590  1.00 40.18  ? 538 HOH D O   1 
HETATM 12667 O  O   . HOH V 3 .   ? 77.657  110.397 71.405  1.00 36.18  ? 539 HOH D O   1 
HETATM 12668 O  O   . HOH V 3 .   ? 72.231  101.900 55.553  1.00 48.03  ? 540 HOH D O   1 
HETATM 12669 O  O   . HOH V 3 .   ? 80.828  127.568 58.822  1.00 44.60  ? 541 HOH D O   1 
HETATM 12670 O  O   . HOH V 3 .   ? 74.143  107.719 70.920  1.00 37.94  ? 542 HOH D O   1 
HETATM 12671 O  O   . HOH V 3 .   ? 83.187  127.485 62.249  1.00 43.17  ? 543 HOH D O   1 
HETATM 12672 O  O   . HOH V 3 .   ? 73.185  102.452 49.425  1.00 27.20  ? 544 HOH D O   1 
HETATM 12673 O  O   . HOH V 3 .   ? 71.926  105.651 59.910  1.00 39.38  ? 545 HOH D O   1 
HETATM 12674 O  O   . HOH V 3 .   ? 97.958  102.192 38.978  1.00 44.90  ? 546 HOH D O   1 
HETATM 12675 O  O   . HOH W 3 .   ? 72.658  101.429 83.726  1.00 46.66  ? 401 HOH E O   1 
HETATM 12676 O  O   . HOH W 3 .   ? 53.517  131.438 77.540  1.00 46.09  ? 402 HOH E O   1 
HETATM 12677 O  O   . HOH W 3 .   ? 49.142  116.862 84.621  1.00 40.03  ? 403 HOH E O   1 
HETATM 12678 O  O   . HOH W 3 .   ? 78.055  105.599 81.447  1.00 43.44  ? 404 HOH E O   1 
HETATM 12679 O  O   . HOH W 3 .   ? 66.272  108.635 61.446  1.00 29.79  ? 405 HOH E O   1 
HETATM 12680 O  O   . HOH W 3 .   ? 56.629  95.400  67.794  1.00 22.53  ? 406 HOH E O   1 
HETATM 12681 O  O   . HOH W 3 .   ? 50.323  91.378  90.196  1.00 43.69  ? 407 HOH E O   1 
HETATM 12682 O  O   . HOH W 3 .   ? 61.949  112.880 93.228  1.00 40.23  ? 408 HOH E O   1 
HETATM 12683 O  O   . HOH W 3 .   ? 54.097  106.794 81.573  1.00 31.28  ? 409 HOH E O   1 
HETATM 12684 O  O   . HOH W 3 .   ? 49.632  97.489  91.194  1.00 44.43  ? 410 HOH E O   1 
HETATM 12685 O  O   . HOH W 3 .   ? 56.383  104.356 83.721  1.00 20.24  ? 411 HOH E O   1 
HETATM 12686 O  O   . HOH W 3 .   ? 60.386  99.758  69.905  1.00 23.92  ? 412 HOH E O   1 
HETATM 12687 O  O   . HOH W 3 .   ? 62.842  118.405 95.984  1.00 46.72  ? 413 HOH E O   1 
HETATM 12688 O  O   . HOH W 3 .   ? 41.567  98.495  68.160  1.00 43.09  ? 414 HOH E O   1 
HETATM 12689 O  O   . HOH W 3 .   ? 51.733  110.503 78.889  1.00 28.48  ? 415 HOH E O   1 
HETATM 12690 O  O   . HOH W 3 .   ? 41.340  109.249 66.721  1.00 35.66  ? 416 HOH E O   1 
HETATM 12691 O  O   . HOH W 3 .   ? 66.839  120.380 88.770  1.00 32.67  ? 417 HOH E O   1 
HETATM 12692 O  O   . HOH W 3 .   ? 69.887  106.242 82.732  1.00 29.75  ? 418 HOH E O   1 
HETATM 12693 O  O   . HOH W 3 .   ? 47.545  103.970 57.363  1.00 28.87  ? 419 HOH E O   1 
HETATM 12694 O  O   . HOH W 3 .   ? 40.514  112.153 86.808  1.00 46.61  ? 420 HOH E O   1 
HETATM 12695 O  O   . HOH W 3 .   ? 70.979  111.706 79.906  1.00 29.46  ? 421 HOH E O   1 
HETATM 12696 O  O   . HOH W 3 .   ? 46.012  113.796 72.909  1.00 29.89  ? 422 HOH E O   1 
HETATM 12697 O  O   . HOH W 3 .   ? 36.452  100.832 76.793  1.00 49.42  ? 423 HOH E O   1 
HETATM 12698 O  O   . HOH W 3 .   ? 50.353  101.461 67.954  1.00 30.46  ? 424 HOH E O   1 
HETATM 12699 O  O   . HOH W 3 .   ? 71.833  104.342 83.137  1.00 33.19  ? 425 HOH E O   1 
HETATM 12700 O  O   . HOH W 3 .   ? 47.533  102.487 75.371  1.00 35.44  ? 426 HOH E O   1 
HETATM 12701 O  O   . HOH W 3 .   ? 66.691  103.511 92.911  1.00 31.66  ? 427 HOH E O   1 
HETATM 12702 O  O   . HOH W 3 .   ? 58.041  102.151 58.320  1.00 38.64  ? 428 HOH E O   1 
HETATM 12703 O  O   . HOH W 3 .   ? 58.016  99.743  91.993  1.00 41.11  ? 429 HOH E O   1 
HETATM 12704 O  O   . HOH W 3 .   ? 54.327  116.277 91.363  1.00 44.72  ? 430 HOH E O   1 
HETATM 12705 O  O   . HOH W 3 .   ? 68.456  115.758 92.791  1.00 34.86  ? 431 HOH E O   1 
HETATM 12706 O  O   . HOH W 3 .   ? 51.507  96.391  79.552  1.00 32.51  ? 432 HOH E O   1 
HETATM 12707 O  O   . HOH W 3 .   ? 41.197  115.340 86.500  1.00 44.76  ? 433 HOH E O   1 
HETATM 12708 O  O   . HOH W 3 .   ? 70.728  107.583 64.649  1.00 31.75  ? 434 HOH E O   1 
HETATM 12709 O  O   . HOH W 3 .   ? 69.535  89.795  92.320  1.00 49.99  ? 435 HOH E O   1 
HETATM 12710 O  O   . HOH W 3 .   ? 44.512  98.500  58.157  1.00 23.17  ? 436 HOH E O   1 
HETATM 12711 O  O   . HOH W 3 .   ? 64.479  96.568  90.769  1.00 37.55  ? 437 HOH E O   1 
HETATM 12712 O  O   . HOH W 3 .   ? 56.758  130.313 84.010  1.00 42.56  ? 438 HOH E O   1 
HETATM 12713 O  O   . HOH W 3 .   ? 46.536  121.498 69.015  1.00 45.39  ? 439 HOH E O   1 
HETATM 12714 O  O   . HOH W 3 .   ? 55.743  97.223  74.643  1.00 19.64  ? 440 HOH E O   1 
HETATM 12715 O  O   . HOH W 3 .   ? 58.574  96.857  66.475  1.00 26.07  ? 441 HOH E O   1 
HETATM 12716 O  O   . HOH W 3 .   ? 56.985  113.380 91.450  1.00 41.18  ? 442 HOH E O   1 
HETATM 12717 O  O   . HOH W 3 .   ? 51.108  104.062 86.565  1.00 41.60  ? 443 HOH E O   1 
HETATM 12718 O  O   . HOH W 3 .   ? 51.670  105.159 80.749  1.00 31.65  ? 444 HOH E O   1 
HETATM 12719 O  O   . HOH W 3 .   ? 48.720  118.000 77.684  1.00 35.34  ? 445 HOH E O   1 
HETATM 12720 O  O   . HOH W 3 .   ? 61.609  93.167  73.014  1.00 30.01  ? 446 HOH E O   1 
HETATM 12721 O  O   . HOH W 3 .   ? 67.601  94.547  79.788  1.00 27.18  ? 447 HOH E O   1 
HETATM 12722 O  O   . HOH W 3 .   ? 59.548  106.875 55.839  1.00 27.01  ? 448 HOH E O   1 
HETATM 12723 O  O   . HOH W 3 .   ? 55.829  89.922  66.362  1.00 26.85  ? 449 HOH E O   1 
HETATM 12724 O  O   . HOH W 3 .   ? 62.365  117.486 62.256  1.00 49.58  ? 450 HOH E O   1 
HETATM 12725 O  O   . HOH W 3 .   ? 60.954  124.636 74.028  1.00 33.31  ? 451 HOH E O   1 
HETATM 12726 O  O   . HOH W 3 .   ? 48.548  110.618 69.322  1.00 25.58  ? 452 HOH E O   1 
HETATM 12727 O  O   . HOH W 3 .   ? 56.085  95.210  76.739  1.00 18.09  ? 453 HOH E O   1 
HETATM 12728 O  O   . HOH W 3 .   ? 32.786  91.033  81.431  1.00 51.30  ? 454 HOH E O   1 
HETATM 12729 O  O   . HOH W 3 .   ? 55.220  105.293 57.427  1.00 24.01  ? 455 HOH E O   1 
HETATM 12730 O  O   . HOH W 3 .   ? 52.087  91.565  79.325  1.00 35.21  ? 456 HOH E O   1 
HETATM 12731 O  O   . HOH W 3 .   ? 54.205  108.899 79.739  1.00 30.58  ? 457 HOH E O   1 
HETATM 12732 O  O   . HOH W 3 .   ? 46.197  96.655  57.636  1.00 21.91  ? 458 HOH E O   1 
HETATM 12733 O  O   . HOH W 3 .   ? 35.454  114.794 66.269  1.00 45.87  ? 459 HOH E O   1 
HETATM 12734 O  O   . HOH W 3 .   ? 57.356  92.612  65.262  1.00 43.06  ? 460 HOH E O   1 
HETATM 12735 O  O   . HOH W 3 .   ? 33.362  116.293 73.734  1.00 48.23  ? 461 HOH E O   1 
HETATM 12736 O  O   . HOH W 3 .   ? 73.643  107.767 73.577  1.00 27.40  ? 462 HOH E O   1 
HETATM 12737 O  O   . HOH W 3 .   ? 66.677  105.248 58.218  1.00 20.70  ? 463 HOH E O   1 
HETATM 12738 O  O   . HOH W 3 .   ? 72.156  117.138 75.502  1.00 34.24  ? 464 HOH E O   1 
HETATM 12739 O  O   . HOH W 3 .   ? 65.358  111.940 59.918  1.00 26.30  ? 465 HOH E O   1 
HETATM 12740 O  O   . HOH W 3 .   ? 56.800  88.837  79.777  1.00 27.16  ? 466 HOH E O   1 
HETATM 12741 O  O   . HOH W 3 .   ? 66.729  112.445 63.328  1.00 30.64  ? 467 HOH E O   1 
HETATM 12742 O  O   . HOH W 3 .   ? 71.641  96.765  80.798  1.00 38.14  ? 468 HOH E O   1 
HETATM 12743 O  O   . HOH W 3 .   ? 67.611  118.523 94.031  1.00 39.61  ? 469 HOH E O   1 
HETATM 12744 O  O   . HOH W 3 .   ? 45.320  108.265 62.934  1.00 32.19  ? 470 HOH E O   1 
HETATM 12745 O  O   . HOH W 3 .   ? 45.707  89.038  79.874  1.00 40.28  ? 471 HOH E O   1 
HETATM 12746 O  O   . HOH W 3 .   ? 73.289  112.324 69.311  1.00 22.07  ? 472 HOH E O   1 
HETATM 12747 O  O   . HOH W 3 .   ? 48.472  119.580 75.450  1.00 36.37  ? 473 HOH E O   1 
HETATM 12748 O  O   . HOH W 3 .   ? 46.219  118.710 89.758  1.00 43.97  ? 474 HOH E O   1 
HETATM 12749 O  O   . HOH W 3 .   ? 64.286  125.858 84.463  1.00 34.11  ? 475 HOH E O   1 
HETATM 12750 O  O   . HOH W 3 .   ? 40.992  102.688 65.666  1.00 42.38  ? 476 HOH E O   1 
HETATM 12751 O  O   . HOH W 3 .   ? 34.739  103.124 83.383  1.00 56.39  ? 477 HOH E O   1 
HETATM 12752 O  O   . HOH W 3 .   ? 42.157  116.363 66.275  1.00 37.78  ? 478 HOH E O   1 
HETATM 12753 O  O   . HOH W 3 .   ? 56.282  97.648  92.304  1.00 43.56  ? 479 HOH E O   1 
HETATM 12754 O  O   . HOH W 3 .   ? 60.337  98.885  92.015  1.00 35.50  ? 480 HOH E O   1 
HETATM 12755 O  O   . HOH W 3 .   ? 31.623  97.412  85.785  1.00 54.87  ? 481 HOH E O   1 
HETATM 12756 O  O   . HOH W 3 .   ? 66.575  101.149 62.186  1.00 35.53  ? 482 HOH E O   1 
HETATM 12757 O  O   . HOH W 3 .   ? 46.913  116.605 88.098  1.00 40.69  ? 483 HOH E O   1 
HETATM 12758 O  O   . HOH W 3 .   ? 70.149  91.233  84.910  1.00 31.07  ? 484 HOH E O   1 
HETATM 12759 O  O   . HOH W 3 .   ? 63.424  89.081  76.483  1.00 26.30  ? 485 HOH E O   1 
HETATM 12760 O  O   . HOH W 3 .   ? 51.344  128.421 90.482  1.00 38.59  ? 486 HOH E O   1 
HETATM 12761 O  O   . HOH W 3 .   ? 76.649  108.068 77.563  1.00 50.84  ? 487 HOH E O   1 
HETATM 12762 O  O   . HOH W 3 .   ? 60.140  105.792 70.897  1.00 18.57  ? 488 HOH E O   1 
HETATM 12763 O  O   . HOH W 3 .   ? 52.792  93.996  79.055  1.00 32.66  ? 489 HOH E O   1 
HETATM 12764 O  O   . HOH W 3 .   ? 63.470  96.961  68.121  1.00 31.15  ? 490 HOH E O   1 
HETATM 12765 O  O   . HOH W 3 .   ? 61.227  128.812 82.732  1.00 40.49  ? 491 HOH E O   1 
HETATM 12766 O  O   . HOH W 3 .   ? 61.739  86.990  83.583  1.00 36.75  ? 492 HOH E O   1 
HETATM 12767 O  O   . HOH W 3 .   ? 62.896  89.047  69.892  1.00 22.52  ? 493 HOH E O   1 
HETATM 12768 O  O   . HOH W 3 .   ? 55.410  125.614 70.155  1.00 40.46  ? 494 HOH E O   1 
HETATM 12769 O  O   . HOH W 3 .   ? 42.673  112.330 80.528  1.00 42.98  ? 495 HOH E O   1 
HETATM 12770 O  O   . HOH W 3 .   ? 57.774  130.446 76.140  1.00 39.33  ? 496 HOH E O   1 
HETATM 12771 O  O   . HOH W 3 .   ? 71.582  118.179 91.050  1.00 35.36  ? 497 HOH E O   1 
HETATM 12772 O  O   . HOH W 3 .   ? 69.918  114.189 72.731  1.00 28.64  ? 498 HOH E O   1 
HETATM 12773 O  O   . HOH W 3 .   ? 54.918  126.173 79.870  1.00 42.89  ? 499 HOH E O   1 
HETATM 12774 O  O   . HOH W 3 .   ? 38.743  107.532 66.466  1.00 37.96  ? 500 HOH E O   1 
HETATM 12775 O  O   . HOH W 3 .   ? 72.434  100.584 89.394  1.00 41.38  ? 501 HOH E O   1 
HETATM 12776 O  O   . HOH W 3 .   ? 63.566  91.582  87.821  1.00 39.01  ? 502 HOH E O   1 
HETATM 12777 O  O   . HOH W 3 .   ? 66.514  94.458  72.822  1.00 29.43  ? 503 HOH E O   1 
HETATM 12778 O  O   . HOH W 3 .   ? 64.849  88.340  81.704  1.00 29.09  ? 504 HOH E O   1 
HETATM 12779 O  O   . HOH W 3 .   ? 55.298  82.856  83.443  1.00 36.96  ? 505 HOH E O   1 
HETATM 12780 O  O   . HOH W 3 .   ? 54.314  90.161  80.397  1.00 28.54  ? 506 HOH E O   1 
HETATM 12781 O  O   . HOH W 3 .   ? 56.788  91.488  91.540  1.00 50.69  ? 507 HOH E O   1 
HETATM 12782 O  O   . HOH W 3 .   ? 52.285  116.581 92.251  1.00 54.86  ? 508 HOH E O   1 
HETATM 12783 O  O   . HOH W 3 .   ? 70.336  125.271 80.598  1.00 47.78  ? 509 HOH E O   1 
HETATM 12784 O  O   . HOH W 3 .   ? 69.018  98.313  76.273  1.00 34.18  ? 510 HOH E O   1 
HETATM 12785 O  O   . HOH W 3 .   ? 47.271  120.644 64.777  1.00 45.05  ? 511 HOH E O   1 
HETATM 12786 O  O   . HOH W 3 .   ? 72.330  105.478 89.754  1.00 31.97  ? 512 HOH E O   1 
HETATM 12787 O  O   . HOH W 3 .   ? 68.361  101.229 93.995  1.00 42.31  ? 513 HOH E O   1 
HETATM 12788 O  O   . HOH W 3 .   ? 49.267  121.864 77.034  1.00 37.75  ? 514 HOH E O   1 
HETATM 12789 O  O   . HOH W 3 .   ? 42.628  102.652 67.809  1.00 38.90  ? 515 HOH E O   1 
HETATM 12790 O  O   . HOH W 3 .   ? 45.284  95.213  70.080  1.00 37.05  ? 516 HOH E O   1 
HETATM 12791 O  O   . HOH W 3 .   ? 69.082  109.157 63.352  1.00 27.97  ? 517 HOH E O   1 
HETATM 12792 O  O   . HOH W 3 .   ? 38.620  122.305 83.033  1.00 51.29  ? 518 HOH E O   1 
HETATM 12793 O  O   . HOH W 3 .   ? 47.755  109.003 60.806  1.00 40.44  ? 519 HOH E O   1 
HETATM 12794 O  O   . HOH W 3 .   ? 43.703  114.561 64.679  1.00 35.21  ? 520 HOH E O   1 
HETATM 12795 O  O   . HOH W 3 .   ? 57.140  101.379 61.193  1.00 44.10  ? 521 HOH E O   1 
HETATM 12796 O  O   . HOH W 3 .   ? 65.564  124.073 78.878  1.00 44.33  ? 522 HOH E O   1 
HETATM 12797 O  O   . HOH W 3 .   ? 73.914  97.854  67.886  1.00 48.98  ? 523 HOH E O   1 
HETATM 12798 O  O   . HOH W 3 .   ? 61.372  91.081  70.851  1.00 25.89  ? 524 HOH E O   1 
HETATM 12799 O  O   . HOH W 3 .   ? 33.364  121.329 78.455  1.00 53.98  ? 525 HOH E O   1 
HETATM 12800 O  O   . HOH W 3 .   ? 55.594  115.968 62.132  1.00 40.32  ? 526 HOH E O   1 
HETATM 12801 O  O   . HOH W 3 .   ? 34.760  104.002 78.081  1.00 49.23  ? 527 HOH E O   1 
HETATM 12802 O  O   . HOH W 3 .   ? 55.387  100.481 94.713  1.00 50.46  ? 528 HOH E O   1 
HETATM 12803 O  O   . HOH W 3 .   ? 58.811  80.734  80.981  1.00 37.64  ? 529 HOH E O   1 
HETATM 12804 O  O   . HOH W 3 .   ? 61.702  104.272 55.705  1.00 37.83  ? 530 HOH E O   1 
HETATM 12805 O  O   . HOH W 3 .   ? 63.865  114.046 61.504  1.00 34.12  ? 531 HOH E O   1 
HETATM 12806 O  O   . HOH W 3 .   ? 75.788  99.155  81.472  1.00 38.60  ? 532 HOH E O   1 
HETATM 12807 O  O   . HOH W 3 .   ? 63.504  102.893 64.455  1.00 23.96  ? 533 HOH E O   1 
HETATM 12808 O  O   . HOH W 3 .   ? 73.728  99.215  86.987  1.00 41.33  ? 534 HOH E O   1 
HETATM 12809 O  O   . HOH W 3 .   ? 68.572  121.709 87.175  1.00 41.36  ? 535 HOH E O   1 
HETATM 12810 O  O   . HOH W 3 .   ? 58.830  122.266 68.452  1.00 37.22  ? 536 HOH E O   1 
HETATM 12811 O  O   . HOH W 3 .   ? 71.759  109.166 67.253  1.00 30.55  ? 537 HOH E O   1 
HETATM 12812 O  O   . HOH W 3 .   ? 69.695  108.242 60.306  1.00 31.23  ? 538 HOH E O   1 
HETATM 12813 O  O   . HOH W 3 .   ? 33.183  110.989 63.508  1.00 53.64  ? 539 HOH E O   1 
HETATM 12814 O  O   . HOH W 3 .   ? 55.339  102.546 58.990  1.00 31.47  ? 540 HOH E O   1 
HETATM 12815 O  O   . HOH W 3 .   ? 62.728  81.379  78.646  1.00 40.55  ? 541 HOH E O   1 
HETATM 12816 O  O   . HOH W 3 .   ? 40.105  105.356 63.194  1.00 43.82  ? 542 HOH E O   1 
HETATM 12817 O  O   . HOH W 3 .   ? 57.573  115.203 93.751  1.00 42.25  ? 543 HOH E O   1 
HETATM 12818 O  O   . HOH W 3 .   ? 56.498  115.078 96.031  1.00 42.15  ? 544 HOH E O   1 
HETATM 12819 O  O   . HOH W 3 .   ? 60.126  114.754 93.638  1.00 43.06  ? 545 HOH E O   1 
HETATM 12820 O  O   . HOH W 3 .   ? 36.311  118.955 83.515  1.00 52.20  ? 546 HOH E O   1 
HETATM 12821 O  O   . HOH W 3 .   ? 48.759  123.810 75.030  1.00 38.49  ? 547 HOH E O   1 
HETATM 12822 O  O   . HOH W 3 .   ? 71.394  120.483 89.757  1.00 41.09  ? 548 HOH E O   1 
HETATM 12823 O  O   . HOH W 3 .   ? 55.985  117.537 94.673  1.00 33.79  ? 549 HOH E O   1 
HETATM 12824 O  O   . HOH W 3 .   ? 56.803  80.755  82.409  1.00 42.29  ? 550 HOH E O   1 
HETATM 12825 O  O   . HOH W 3 .   ? 61.427  81.861  76.743  1.00 43.08  ? 551 HOH E O   1 
HETATM 12826 O  O   . HOH W 3 .   ? 66.687  97.202  69.799  1.00 30.69  ? 552 HOH E O   1 
HETATM 12827 O  O   . HOH W 3 .   ? 60.833  95.189  66.834  1.00 30.41  ? 553 HOH E O   1 
HETATM 12828 O  O   . HOH W 3 .   ? 64.698  92.329  90.600  1.00 42.59  ? 554 HOH E O   1 
HETATM 12829 O  O   . HOH W 3 .   ? 38.724  104.891 65.140  1.00 51.95  ? 555 HOH E O   1 
HETATM 12830 O  O   . HOH W 3 .   ? 64.437  96.529  70.759  1.00 26.99  ? 556 HOH E O   1 
HETATM 12831 O  O   . HOH W 3 .   ? 63.886  94.321  71.911  1.00 31.92  ? 557 HOH E O   1 
HETATM 12832 O  O   . HOH W 3 .   ? 54.657  95.565  65.553  1.00 23.32  ? 558 HOH E O   1 
HETATM 12833 O  O   . HOH W 3 .   ? 72.903  97.054  59.031  1.00 55.37  ? 559 HOH E O   1 
HETATM 12834 O  O   . HOH W 3 .   ? 72.694  96.931  77.944  1.00 39.68  ? 560 HOH E O   1 
HETATM 12835 O  O   . HOH W 3 .   ? 70.908  100.059 77.476  1.00 42.03  ? 561 HOH E O   1 
HETATM 12836 O  O   . HOH W 3 .   ? 50.530  125.639 73.723  1.00 43.58  ? 562 HOH E O   1 
HETATM 12837 O  O   . HOH W 3 .   ? 49.287  129.162 89.004  1.00 36.66  ? 563 HOH E O   1 
HETATM 12838 O  O   . HOH W 3 .   ? 42.181  100.171 96.470  1.00 56.24  ? 564 HOH E O   1 
HETATM 12839 O  O   . HOH W 3 .   ? 58.260  96.111  63.865  1.00 39.75  ? 565 HOH E O   1 
HETATM 12840 O  O   . HOH W 3 .   ? 35.162  112.855 63.481  1.00 50.00  ? 566 HOH E O   1 
HETATM 12841 O  O   . HOH W 3 .   ? 57.152  93.174  93.445  1.00 54.09  ? 567 HOH E O   1 
HETATM 12842 O  O   . HOH W 3 .   ? 55.753  119.445 93.583  1.00 51.75  ? 568 HOH E O   1 
HETATM 12843 O  O   . HOH W 3 .   ? 41.974  118.971 65.340  1.00 44.98  ? 569 HOH E O   1 
HETATM 12844 O  O   . HOH W 3 .   ? 56.010  96.431  63.850  1.00 50.35  ? 570 HOH E O   1 
HETATM 12845 O  O   . HOH W 3 .   ? 71.663  122.745 90.143  1.00 45.07  ? 571 HOH E O   1 
HETATM 12846 O  O   . HOH X 3 .   ? 63.953  62.408  42.187  1.00 34.76  ? 401 HOH F O   1 
HETATM 12847 O  O   . HOH X 3 .   ? 96.984  68.799  31.711  1.00 51.87  ? 402 HOH F O   1 
HETATM 12848 O  O   . HOH X 3 .   ? 68.100  71.323  20.924  1.00 45.08  ? 403 HOH F O   1 
HETATM 12849 O  O   . HOH X 3 .   ? 85.183  69.933  28.562  1.00 46.52  ? 404 HOH F O   1 
HETATM 12850 O  O   . HOH X 3 .   ? 77.925  95.915  45.772  1.00 25.49  ? 405 HOH F O   1 
HETATM 12851 O  O   . HOH X 3 .   ? 63.916  78.419  30.975  1.00 29.66  ? 406 HOH F O   1 
HETATM 12852 O  O   . HOH X 3 .   ? 66.002  91.002  40.211  1.00 34.10  ? 407 HOH F O   1 
HETATM 12853 O  O   . HOH X 3 .   ? 89.327  78.420  36.301  1.00 39.68  ? 408 HOH F O   1 
HETATM 12854 O  O   . HOH X 3 .   ? 86.194  83.645  23.073  1.00 47.58  ? 409 HOH F O   1 
HETATM 12855 O  O   . HOH X 3 .   ? 101.864 75.073  36.056  1.00 57.23  ? 410 HOH F O   1 
HETATM 12856 O  O   . HOH X 3 .   ? 69.341  78.226  54.815  1.00 23.37  ? 411 HOH F O   1 
HETATM 12857 O  O   . HOH X 3 .   ? 79.185  64.263  39.927  1.00 40.71  ? 412 HOH F O   1 
HETATM 12858 O  O   . HOH X 3 .   ? 62.271  79.341  47.375  1.00 38.16  ? 413 HOH F O   1 
HETATM 12859 O  O   . HOH X 3 .   ? 93.013  85.557  38.860  1.00 45.20  ? 414 HOH F O   1 
HETATM 12860 O  O   . HOH X 3 .   ? 71.191  93.305  41.024  1.00 34.84  ? 415 HOH F O   1 
HETATM 12861 O  O   . HOH X 3 .   ? 81.543  92.720  47.570  1.00 30.47  ? 416 HOH F O   1 
HETATM 12862 O  O   . HOH X 3 .   ? 70.925  68.016  54.856  1.00 24.14  ? 417 HOH F O   1 
HETATM 12863 O  O   . HOH X 3 .   ? 65.490  73.068  54.184  1.00 25.20  ? 418 HOH F O   1 
HETATM 12864 O  O   . HOH X 3 .   ? 65.228  62.907  20.636  1.00 44.87  ? 419 HOH F O   1 
HETATM 12865 O  O   . HOH X 3 .   ? 81.197  59.029  45.842  1.00 47.68  ? 420 HOH F O   1 
HETATM 12866 O  O   . HOH X 3 .   ? 60.205  73.560  36.529  1.00 31.35  ? 421 HOH F O   1 
HETATM 12867 O  O   . HOH X 3 .   ? 85.809  71.251  48.020  1.00 46.14  ? 422 HOH F O   1 
HETATM 12868 O  O   . HOH X 3 .   ? 74.849  68.707  39.178  1.00 29.61  ? 423 HOH F O   1 
HETATM 12869 O  O   . HOH X 3 .   ? 73.090  82.860  55.861  1.00 34.87  ? 424 HOH F O   1 
HETATM 12870 O  O   . HOH X 3 .   ? 58.124  67.581  47.996  1.00 30.44  ? 425 HOH F O   1 
HETATM 12871 O  O   . HOH X 3 .   ? 82.972  80.571  48.541  1.00 31.18  ? 426 HOH F O   1 
HETATM 12872 O  O   . HOH X 3 .   ? 87.826  78.122  29.640  1.00 45.35  ? 427 HOH F O   1 
HETATM 12873 O  O   . HOH X 3 .   ? 82.025  73.784  36.015  1.00 34.37  ? 428 HOH F O   1 
HETATM 12874 O  O   . HOH X 3 .   ? 86.241  89.524  54.744  1.00 38.44  ? 429 HOH F O   1 
HETATM 12875 O  O   . HOH X 3 .   ? 93.873  81.392  43.664  1.00 42.81  ? 430 HOH F O   1 
HETATM 12876 O  O   . HOH X 3 .   ? 80.207  76.520  57.846  1.00 25.45  ? 431 HOH F O   1 
HETATM 12877 O  O   . HOH X 3 .   ? 74.173  72.372  50.065  1.00 23.99  ? 432 HOH F O   1 
HETATM 12878 O  O   . HOH X 3 .   ? 88.507  90.307  50.291  1.00 36.12  ? 433 HOH F O   1 
HETATM 12879 O  O   . HOH X 3 .   ? 68.713  90.691  47.175  1.00 37.66  ? 434 HOH F O   1 
HETATM 12880 O  O   . HOH X 3 .   ? 104.174 78.026  36.188  1.00 56.91  ? 435 HOH F O   1 
HETATM 12881 O  O   . HOH X 3 .   ? 73.981  83.028  51.488  1.00 24.72  ? 436 HOH F O   1 
HETATM 12882 O  O   . HOH X 3 .   ? 57.391  66.871  37.378  1.00 35.31  ? 437 HOH F O   1 
HETATM 12883 O  O   . HOH X 3 .   ? 87.017  81.601  39.712  1.00 34.52  ? 438 HOH F O   1 
HETATM 12884 O  O   . HOH X 3 .   ? 67.458  60.700  40.415  1.00 39.14  ? 439 HOH F O   1 
HETATM 12885 O  O   . HOH X 3 .   ? 72.777  81.308  20.893  1.00 39.46  ? 440 HOH F O   1 
HETATM 12886 O  O   . HOH X 3 .   ? 75.152  74.743  49.139  1.00 23.93  ? 441 HOH F O   1 
HETATM 12887 O  O   . HOH X 3 .   ? 62.407  73.956  35.366  1.00 31.79  ? 442 HOH F O   1 
HETATM 12888 O  O   . HOH X 3 .   ? 88.740  87.950  44.784  1.00 36.31  ? 443 HOH F O   1 
HETATM 12889 O  O   . HOH X 3 .   ? 65.925  90.370  47.392  1.00 51.05  ? 444 HOH F O   1 
HETATM 12890 O  O   . HOH X 3 .   ? 83.343  91.203  35.731  1.00 46.32  ? 445 HOH F O   1 
HETATM 12891 O  O   . HOH X 3 .   ? 72.716  80.960  47.335  1.00 26.18  ? 446 HOH F O   1 
HETATM 12892 O  O   . HOH X 3 .   ? 75.001  64.321  28.306  1.00 43.23  ? 447 HOH F O   1 
HETATM 12893 O  O   . HOH X 3 .   ? 90.502  85.879  44.733  1.00 35.51  ? 448 HOH F O   1 
HETATM 12894 O  O   . HOH X 3 .   ? 62.210  88.983  42.161  1.00 40.21  ? 449 HOH F O   1 
HETATM 12895 O  O   . HOH X 3 .   ? 64.559  78.323  50.029  1.00 27.63  ? 450 HOH F O   1 
HETATM 12896 O  O   . HOH X 3 .   ? 74.575  80.624  58.464  1.00 26.29  ? 451 HOH F O   1 
HETATM 12897 O  O   . HOH X 3 .   ? 63.126  62.863  34.944  1.00 36.20  ? 452 HOH F O   1 
HETATM 12898 O  O   . HOH X 3 .   ? 87.402  87.547  57.290  1.00 22.87  ? 453 HOH F O   1 
HETATM 12899 O  O   . HOH X 3 .   ? 85.005  90.511  52.757  1.00 40.90  ? 454 HOH F O   1 
HETATM 12900 O  O   . HOH X 3 .   ? 83.736  62.683  57.934  1.00 50.44  ? 455 HOH F O   1 
HETATM 12901 O  O   . HOH X 3 .   ? 73.187  95.288  38.734  1.00 29.40  ? 456 HOH F O   1 
HETATM 12902 O  O   . HOH X 3 .   ? 54.097  65.539  42.015  1.00 41.89  ? 457 HOH F O   1 
HETATM 12903 O  O   . HOH X 3 .   ? 85.456  75.600  54.088  1.00 40.29  ? 458 HOH F O   1 
HETATM 12904 O  O   . HOH X 3 .   ? 92.835  83.900  43.396  1.00 40.40  ? 459 HOH F O   1 
HETATM 12905 O  O   . HOH X 3 .   ? 89.474  87.258  55.796  1.00 27.00  ? 460 HOH F O   1 
HETATM 12906 O  O   . HOH X 3 .   ? 70.427  59.954  40.335  1.00 37.67  ? 461 HOH F O   1 
HETATM 12907 O  O   . HOH X 3 .   ? 87.804  77.787  26.526  1.00 45.23  ? 462 HOH F O   1 
HETATM 12908 O  O   . HOH X 3 .   ? 66.584  65.138  61.204  1.00 37.28  ? 463 HOH F O   1 
HETATM 12909 O  O   . HOH X 3 .   ? 79.096  89.272  27.871  1.00 44.64  ? 464 HOH F O   1 
HETATM 12910 O  O   . HOH X 3 .   ? 84.701  87.199  24.722  1.00 46.64  ? 465 HOH F O   1 
HETATM 12911 O  O   . HOH X 3 .   ? 75.405  80.752  52.990  1.00 27.99  ? 466 HOH F O   1 
HETATM 12912 O  O   . HOH X 3 .   ? 71.814  80.705  58.047  1.00 33.18  ? 467 HOH F O   1 
HETATM 12913 O  O   . HOH X 3 .   ? 63.991  88.787  33.553  1.00 28.21  ? 468 HOH F O   1 
HETATM 12914 O  O   . HOH X 3 .   ? 78.465  84.488  23.068  1.00 46.87  ? 469 HOH F O   1 
HETATM 12915 O  O   . HOH X 3 .   ? 92.189  80.701  50.137  1.00 41.68  ? 470 HOH F O   1 
HETATM 12916 O  O   . HOH X 3 .   ? 81.623  87.554  27.497  1.00 44.14  ? 471 HOH F O   1 
HETATM 12917 O  O   . HOH X 3 .   ? 74.375  81.782  41.458  1.00 25.72  ? 472 HOH F O   1 
HETATM 12918 O  O   . HOH X 3 .   ? 91.475  64.151  33.551  1.00 49.72  ? 473 HOH F O   1 
HETATM 12919 O  O   . HOH X 3 .   ? 77.248  93.941  33.167  1.00 42.88  ? 474 HOH F O   1 
HETATM 12920 O  O   . HOH X 3 .   ? 63.919  63.316  47.731  1.00 31.54  ? 475 HOH F O   1 
HETATM 12921 O  O   . HOH X 3 .   ? 75.006  95.437  47.537  1.00 28.90  ? 476 HOH F O   1 
HETATM 12922 O  O   . HOH X 3 .   ? 77.917  88.566  49.364  1.00 32.63  ? 477 HOH F O   1 
HETATM 12923 O  O   . HOH X 3 .   ? 67.159  78.773  56.890  1.00 23.13  ? 478 HOH F O   1 
HETATM 12924 O  O   . HOH X 3 .   ? 62.120  72.691  47.242  1.00 26.11  ? 479 HOH F O   1 
HETATM 12925 O  O   . HOH X 3 .   ? 77.970  68.696  49.279  1.00 35.91  ? 480 HOH F O   1 
HETATM 12926 O  O   . HOH X 3 .   ? 62.503  68.256  52.761  1.00 32.92  ? 481 HOH F O   1 
HETATM 12927 O  O   . HOH X 3 .   ? 66.812  67.549  19.841  1.00 50.46  ? 482 HOH F O   1 
HETATM 12928 O  O   . HOH X 3 .   ? 71.526  92.785  36.928  1.00 32.28  ? 483 HOH F O   1 
HETATM 12929 O  O   . HOH X 3 .   ? 70.478  62.629  58.914  1.00 36.25  ? 484 HOH F O   1 
HETATM 12930 O  O   . HOH X 3 .   ? 55.716  74.436  41.171  1.00 32.66  ? 485 HOH F O   1 
HETATM 12931 O  O   . HOH X 3 .   ? 68.522  92.130  38.877  1.00 32.89  ? 486 HOH F O   1 
HETATM 12932 O  O   . HOH X 3 .   ? 58.619  62.859  36.937  1.00 40.22  ? 487 HOH F O   1 
HETATM 12933 O  O   . HOH X 3 .   ? 69.692  83.069  50.212  1.00 34.12  ? 488 HOH F O   1 
HETATM 12934 O  O   . HOH X 3 .   ? 74.211  84.135  20.877  1.00 43.93  ? 489 HOH F O   1 
HETATM 12935 O  O   . HOH X 3 .   ? 61.072  90.637  51.584  1.00 47.61  ? 490 HOH F O   1 
HETATM 12936 O  O   . HOH X 3 .   ? 67.043  85.447  30.985  1.00 29.92  ? 491 HOH F O   1 
HETATM 12937 O  O   . HOH X 3 .   ? 61.537  84.011  36.006  1.00 30.88  ? 492 HOH F O   1 
HETATM 12938 O  O   . HOH X 3 .   ? 58.668  61.193  43.596  1.00 34.68  ? 493 HOH F O   1 
HETATM 12939 O  O   . HOH X 3 .   ? 92.957  70.324  53.107  1.00 49.93  ? 494 HOH F O   1 
HETATM 12940 O  O   . HOH X 3 .   ? 58.988  73.290  44.184  1.00 28.08  ? 495 HOH F O   1 
HETATM 12941 O  O   . HOH X 3 .   ? 68.600  76.717  52.167  1.00 22.39  ? 496 HOH F O   1 
HETATM 12942 O  O   . HOH X 3 .   ? 63.181  77.545  44.368  1.00 37.07  ? 497 HOH F O   1 
HETATM 12943 O  O   . HOH X 3 .   ? 69.407  58.597  47.741  1.00 56.09  ? 498 HOH F O   1 
HETATM 12944 O  O   . HOH X 3 .   ? 90.174  79.073  49.127  1.00 52.67  ? 499 HOH F O   1 
HETATM 12945 O  O   . HOH X 3 .   ? 96.128  80.693  45.663  1.00 44.67  ? 500 HOH F O   1 
HETATM 12946 O  O   . HOH X 3 .   ? 73.294  67.094  53.848  1.00 31.54  ? 501 HOH F O   1 
HETATM 12947 O  O   . HOH X 3 .   ? 68.066  94.311  40.842  1.00 32.63  ? 502 HOH F O   1 
HETATM 12948 O  O   . HOH X 3 .   ? 60.942  61.841  36.016  1.00 41.98  ? 503 HOH F O   1 
HETATM 12949 O  O   . HOH X 3 .   ? 85.958  61.370  35.917  1.00 46.05  ? 504 HOH F O   1 
HETATM 12950 O  O   . HOH X 3 .   ? 58.857  72.889  39.005  1.00 38.14  ? 505 HOH F O   1 
HETATM 12951 O  O   . HOH X 3 .   ? 63.935  69.699  57.734  1.00 45.45  ? 506 HOH F O   1 
HETATM 12952 O  O   . HOH X 3 .   ? 64.693  65.190  54.031  1.00 37.36  ? 507 HOH F O   1 
HETATM 12953 O  O   . HOH X 3 .   ? 90.664  87.644  51.978  1.00 45.52  ? 508 HOH F O   1 
HETATM 12954 O  O   . HOH X 3 .   ? 58.039  81.211  34.259  1.00 39.35  ? 509 HOH F O   1 
HETATM 12955 O  O   . HOH X 3 .   ? 66.188  60.290  28.450  1.00 49.11  ? 510 HOH F O   1 
HETATM 12956 O  O   . HOH X 3 .   ? 71.776  87.637  45.754  1.00 25.99  ? 511 HOH F O   1 
HETATM 12957 O  O   . HOH X 3 .   ? 56.887  75.290  37.516  1.00 48.34  ? 512 HOH F O   1 
HETATM 12958 O  O   . HOH X 3 .   ? 97.200  68.647  28.771  1.00 51.56  ? 513 HOH F O   1 
HETATM 12959 O  O   . HOH X 3 .   ? 76.259  68.808  51.007  1.00 31.04  ? 514 HOH F O   1 
HETATM 12960 O  O   . HOH X 3 .   ? 91.275  90.379  34.143  1.00 47.85  ? 515 HOH F O   1 
HETATM 12961 O  O   . HOH X 3 .   ? 92.610  86.174  41.851  1.00 44.75  ? 516 HOH F O   1 
HETATM 12962 O  O   . HOH X 3 .   ? 65.599  81.759  48.460  1.00 32.00  ? 517 HOH F O   1 
HETATM 12963 O  O   . HOH X 3 .   ? 96.447  58.085  49.277  1.00 58.68  ? 518 HOH F O   1 
HETATM 12964 O  O   . HOH X 3 .   ? 55.803  63.228  41.096  1.00 42.11  ? 519 HOH F O   1 
HETATM 12965 O  O   . HOH X 3 .   ? 80.182  90.767  49.614  1.00 32.52  ? 520 HOH F O   1 
HETATM 12966 O  O   . HOH X 3 .   ? 97.115  83.426  41.241  1.00 55.97  ? 521 HOH F O   1 
HETATM 12967 O  O   . HOH X 3 .   ? 85.065  73.264  44.750  1.00 30.00  ? 522 HOH F O   1 
HETATM 12968 O  O   . HOH X 3 .   ? 56.366  73.082  35.748  1.00 45.84  ? 523 HOH F O   1 
HETATM 12969 O  O   . HOH X 3 .   ? 92.050  89.953  36.850  1.00 45.80  ? 524 HOH F O   1 
HETATM 12970 O  O   . HOH X 3 .   ? 64.974  93.174  47.029  1.00 50.39  ? 525 HOH F O   1 
HETATM 12971 O  O   . HOH X 3 .   ? 94.639  83.887  41.278  1.00 58.52  ? 526 HOH F O   1 
HETATM 12972 O  O   . HOH X 3 .   ? 71.240  82.652  52.556  1.00 30.91  ? 527 HOH F O   1 
HETATM 12973 O  O   . HOH X 3 .   ? 68.602  64.947  26.836  1.00 42.56  ? 528 HOH F O   1 
HETATM 12974 O  O   . HOH X 3 .   ? 59.207  73.192  41.323  1.00 37.75  ? 529 HOH F O   1 
HETATM 12975 O  O   . HOH X 3 .   ? 66.913  94.830  45.620  1.00 44.71  ? 530 HOH F O   1 
HETATM 12976 O  O   . HOH X 3 .   ? 67.646  80.453  49.452  1.00 47.81  ? 531 HOH F O   1 
HETATM 12977 O  O   . HOH X 3 .   ? 59.364  61.369  33.823  1.00 47.74  ? 532 HOH F O   1 
HETATM 12978 O  O   . HOH X 3 .   ? 98.105  58.640  51.494  1.00 52.42  ? 533 HOH F O   1 
HETATM 12979 O  O   . HOH X 3 .   ? 95.201  79.837  48.344  1.00 45.41  ? 534 HOH F O   1 
HETATM 12980 O  O   . HOH X 3 .   ? 70.373  61.788  31.404  1.00 43.84  ? 535 HOH F O   1 
HETATM 12981 O  O   . HOH X 3 .   ? 77.570  82.411  53.913  1.00 24.36  ? 536 HOH F O   1 
HETATM 12982 O  O   . HOH X 3 .   ? 67.385  78.807  51.206  1.00 34.15  ? 537 HOH F O   1 
HETATM 12983 O  O   . HOH X 3 .   ? 58.354  76.303  44.705  1.00 34.10  ? 538 HOH F O   1 
HETATM 12984 O  O   . HOH X 3 .   ? 60.891  76.853  41.907  1.00 47.52  ? 539 HOH F O   1 
HETATM 12985 O  O   . HOH X 3 .   ? 75.967  58.516  25.454  1.00 53.93  ? 540 HOH F O   1 
HETATM 12986 O  O   . HOH X 3 .   ? 62.759  74.670  45.302  1.00 30.73  ? 541 HOH F O   1 
HETATM 12987 O  O   . HOH X 3 .   ? 77.477  84.975  53.353  1.00 36.62  ? 542 HOH F O   1 
HETATM 12988 O  O   . HOH X 3 .   ? 76.193  62.530  23.105  1.00 34.65  ? 543 HOH F O   1 
HETATM 12989 O  O   . HOH X 3 .   ? 79.728  60.979  23.408  1.00 55.50  ? 544 HOH F O   1 
HETATM 12990 O  O   . HOH X 3 .   ? 78.918  62.949  22.456  1.00 56.62  ? 545 HOH F O   1 
# 
