data_9KH5
# 
_entry.id   9KH5 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9KH5         pdb_00009kh5 10.2210/pdb9kh5/pdb 
WWPDB D_1300053531 ?            ?                   
EMDB  EMD-62332    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-02 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9KH5 
_pdbx_database_status.recvd_initial_deposition_date   2024-11-09 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Structure of y+LAT1' 
_pdbx_database_related.db_id          EMD-62332 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              yanrh@sustech.edu.cn 
_pdbx_contact_author.name_first         R.H. 
_pdbx_contact_author.name_last          Yan 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7122-6547 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Yan, R.H.' 1 0000-0002-7122-6547 
'Dai, L.'   2 0009-0001-0330-7994 
'Zhang, T.' 3 0009-0003-0124-6758 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Sci Adv' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2375-2548 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            11 
_citation.language                  ? 
_citation.page_first                eadq0558 
_citation.page_last                 eadq0558 
_citation.title                     
'Structural basis for the substrate recognition and transport mechanism of the human y + LAT1-4F2hc transporter complex.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1126/sciadv.adq0558 
_citation.pdbx_database_id_PubMed   40106545 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Dai, L.'   1  0009-0001-0330-7994 
primary 'Zeng, Q.'  2  0009-0000-8001-5752 
primary 'Zhang, T.' 3  0009-0003-0124-6758 
primary 'Zhang, Y.' 4  0000-0002-2500-0010 
primary 'Shi, Y.'   5  0000-0002-6281-8911 
primary 'Li, Y.'    6  0000-0003-3245-3023 
primary 'Xu, K.'    7  0009-0006-8462-6212 
primary 'Huang, J.' 8  0000-0001-9639-2907 
primary 'Wang, Z.'  9  0000-0001-7473-0354 
primary 'Zhou, Q.'  10 0000-0002-6237-8813 
primary 'Yan, R.'   11 0000-0002-7122-6547 
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 man 
_entity.pdbx_description           'Y+L amino acid transporter 1' 
_entity.formula_weight             57963.137 
_entity.pdbx_number_of_molecules   1 
_entity.pdbx_ec                    ? 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
'Monocyte amino acid permease 2,MOP-2,Solute carrier family 7 member 7,y(+)L-type amino acid transporter 1,Y+LAT1,y+LAT-1' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;DYKDDDDKSGPDEVDASGRVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGV
LIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANY
MVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSS
FAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFAD
QIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLI
NYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIR
VPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN
;
_entity_poly.pdbx_seq_one_letter_code_can   
;DYKDDDDKSGPDEVDASGRVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGV
LIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANY
MVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSS
FAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFAD
QIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLI
NYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIR
VPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ASP n 
1 2   TYR n 
1 3   LYS n 
1 4   ASP n 
1 5   ASP n 
1 6   ASP n 
1 7   ASP n 
1 8   LYS n 
1 9   SER n 
1 10  GLY n 
1 11  PRO n 
1 12  ASP n 
1 13  GLU n 
1 14  VAL n 
1 15  ASP n 
1 16  ALA n 
1 17  SER n 
1 18  GLY n 
1 19  ARG n 
1 20  VAL n 
1 21  ASP n 
1 22  SER n 
1 23  THR n 
1 24  GLU n 
1 25  TYR n 
1 26  GLU n 
1 27  VAL n 
1 28  ALA n 
1 29  SER n 
1 30  GLN n 
1 31  PRO n 
1 32  GLU n 
1 33  VAL n 
1 34  GLU n 
1 35  THR n 
1 36  SER n 
1 37  PRO n 
1 38  LEU n 
1 39  GLY n 
1 40  ASP n 
1 41  GLY n 
1 42  ALA n 
1 43  SER n 
1 44  PRO n 
1 45  GLY n 
1 46  PRO n 
1 47  GLU n 
1 48  GLN n 
1 49  VAL n 
1 50  LYS n 
1 51  LEU n 
1 52  LYS n 
1 53  LYS n 
1 54  GLU n 
1 55  ILE n 
1 56  SER n 
1 57  LEU n 
1 58  LEU n 
1 59  ASN n 
1 60  GLY n 
1 61  VAL n 
1 62  CYS n 
1 63  LEU n 
1 64  ILE n 
1 65  VAL n 
1 66  GLY n 
1 67  ASN n 
1 68  MET n 
1 69  ILE n 
1 70  GLY n 
1 71  SER n 
1 72  GLY n 
1 73  ILE n 
1 74  PHE n 
1 75  VAL n 
1 76  SER n 
1 77  PRO n 
1 78  LYS n 
1 79  GLY n 
1 80  VAL n 
1 81  LEU n 
1 82  ILE n 
1 83  TYR n 
1 84  SER n 
1 85  ALA n 
1 86  SER n 
1 87  PHE n 
1 88  GLY n 
1 89  LEU n 
1 90  SER n 
1 91  LEU n 
1 92  VAL n 
1 93  ILE n 
1 94  TRP n 
1 95  ALA n 
1 96  VAL n 
1 97  GLY n 
1 98  GLY n 
1 99  LEU n 
1 100 PHE n 
1 101 SER n 
1 102 VAL n 
1 103 PHE n 
1 104 GLY n 
1 105 ALA n 
1 106 LEU n 
1 107 CYS n 
1 108 TYR n 
1 109 ALA n 
1 110 GLU n 
1 111 LEU n 
1 112 GLY n 
1 113 THR n 
1 114 THR n 
1 115 ILE n 
1 116 LYS n 
1 117 LYS n 
1 118 SER n 
1 119 GLY n 
1 120 ALA n 
1 121 SER n 
1 122 TYR n 
1 123 ALA n 
1 124 TYR n 
1 125 ILE n 
1 126 LEU n 
1 127 GLU n 
1 128 ALA n 
1 129 PHE n 
1 130 GLY n 
1 131 GLY n 
1 132 PHE n 
1 133 LEU n 
1 134 ALA n 
1 135 PHE n 
1 136 ILE n 
1 137 ARG n 
1 138 LEU n 
1 139 TRP n 
1 140 THR n 
1 141 SER n 
1 142 LEU n 
1 143 LEU n 
1 144 ILE n 
1 145 ILE n 
1 146 GLU n 
1 147 PRO n 
1 148 THR n 
1 149 SER n 
1 150 GLN n 
1 151 ALA n 
1 152 ILE n 
1 153 ILE n 
1 154 ALA n 
1 155 ILE n 
1 156 THR n 
1 157 PHE n 
1 158 ALA n 
1 159 ASN n 
1 160 TYR n 
1 161 MET n 
1 162 VAL n 
1 163 GLN n 
1 164 PRO n 
1 165 LEU n 
1 166 PHE n 
1 167 PRO n 
1 168 SER n 
1 169 CYS n 
1 170 PHE n 
1 171 ALA n 
1 172 PRO n 
1 173 TYR n 
1 174 ALA n 
1 175 ALA n 
1 176 SER n 
1 177 ARG n 
1 178 LEU n 
1 179 LEU n 
1 180 ALA n 
1 181 ALA n 
1 182 ALA n 
1 183 CYS n 
1 184 ILE n 
1 185 CYS n 
1 186 LEU n 
1 187 LEU n 
1 188 THR n 
1 189 PHE n 
1 190 ILE n 
1 191 ASN n 
1 192 CYS n 
1 193 ALA n 
1 194 TYR n 
1 195 VAL n 
1 196 LYS n 
1 197 TRP n 
1 198 GLY n 
1 199 THR n 
1 200 LEU n 
1 201 VAL n 
1 202 GLN n 
1 203 ASP n 
1 204 ILE n 
1 205 PHE n 
1 206 THR n 
1 207 TYR n 
1 208 ALA n 
1 209 LYS n 
1 210 VAL n 
1 211 LEU n 
1 212 ALA n 
1 213 LEU n 
1 214 ILE n 
1 215 ALA n 
1 216 VAL n 
1 217 ILE n 
1 218 VAL n 
1 219 ALA n 
1 220 GLY n 
1 221 ILE n 
1 222 VAL n 
1 223 ARG n 
1 224 LEU n 
1 225 GLY n 
1 226 GLN n 
1 227 GLY n 
1 228 ALA n 
1 229 SER n 
1 230 THR n 
1 231 HIS n 
1 232 PHE n 
1 233 GLU n 
1 234 ASN n 
1 235 SER n 
1 236 PHE n 
1 237 GLU n 
1 238 GLY n 
1 239 SER n 
1 240 SER n 
1 241 PHE n 
1 242 ALA n 
1 243 VAL n 
1 244 GLY n 
1 245 ASP n 
1 246 ILE n 
1 247 ALA n 
1 248 LEU n 
1 249 ALA n 
1 250 LEU n 
1 251 TYR n 
1 252 SER n 
1 253 ALA n 
1 254 LEU n 
1 255 PHE n 
1 256 SER n 
1 257 TYR n 
1 258 SER n 
1 259 GLY n 
1 260 TRP n 
1 261 ASP n 
1 262 THR n 
1 263 LEU n 
1 264 ASN n 
1 265 TYR n 
1 266 VAL n 
1 267 THR n 
1 268 GLU n 
1 269 GLU n 
1 270 ILE n 
1 271 LYS n 
1 272 ASN n 
1 273 PRO n 
1 274 GLU n 
1 275 ARG n 
1 276 ASN n 
1 277 LEU n 
1 278 PRO n 
1 279 LEU n 
1 280 SER n 
1 281 ILE n 
1 282 GLY n 
1 283 ILE n 
1 284 SER n 
1 285 MET n 
1 286 PRO n 
1 287 ILE n 
1 288 VAL n 
1 289 THR n 
1 290 ILE n 
1 291 ILE n 
1 292 TYR n 
1 293 ILE n 
1 294 LEU n 
1 295 THR n 
1 296 ASN n 
1 297 VAL n 
1 298 ALA n 
1 299 TYR n 
1 300 TYR n 
1 301 THR n 
1 302 VAL n 
1 303 LEU n 
1 304 ASP n 
1 305 MET n 
1 306 ARG n 
1 307 ASP n 
1 308 ILE n 
1 309 LEU n 
1 310 ALA n 
1 311 SER n 
1 312 ASP n 
1 313 ALA n 
1 314 VAL n 
1 315 ALA n 
1 316 VAL n 
1 317 THR n 
1 318 PHE n 
1 319 ALA n 
1 320 ASP n 
1 321 GLN n 
1 322 ILE n 
1 323 PHE n 
1 324 GLY n 
1 325 ILE n 
1 326 PHE n 
1 327 ASN n 
1 328 TRP n 
1 329 ILE n 
1 330 ILE n 
1 331 PRO n 
1 332 LEU n 
1 333 SER n 
1 334 VAL n 
1 335 ALA n 
1 336 LEU n 
1 337 SER n 
1 338 CYS n 
1 339 PHE n 
1 340 GLY n 
1 341 GLY n 
1 342 LEU n 
1 343 ASN n 
1 344 ALA n 
1 345 SER n 
1 346 ILE n 
1 347 VAL n 
1 348 ALA n 
1 349 ALA n 
1 350 SER n 
1 351 ARG n 
1 352 LEU n 
1 353 PHE n 
1 354 PHE n 
1 355 VAL n 
1 356 GLY n 
1 357 SER n 
1 358 ARG n 
1 359 GLU n 
1 360 GLY n 
1 361 HIS n 
1 362 LEU n 
1 363 PRO n 
1 364 ASP n 
1 365 ALA n 
1 366 ILE n 
1 367 CYS n 
1 368 MET n 
1 369 ILE n 
1 370 HIS n 
1 371 VAL n 
1 372 GLU n 
1 373 ARG n 
1 374 PHE n 
1 375 THR n 
1 376 PRO n 
1 377 VAL n 
1 378 PRO n 
1 379 SER n 
1 380 LEU n 
1 381 LEU n 
1 382 PHE n 
1 383 ASN n 
1 384 GLY n 
1 385 ILE n 
1 386 MET n 
1 387 ALA n 
1 388 LEU n 
1 389 ILE n 
1 390 TYR n 
1 391 LEU n 
1 392 CYS n 
1 393 VAL n 
1 394 GLU n 
1 395 ASP n 
1 396 ILE n 
1 397 PHE n 
1 398 GLN n 
1 399 LEU n 
1 400 ILE n 
1 401 ASN n 
1 402 TYR n 
1 403 TYR n 
1 404 SER n 
1 405 PHE n 
1 406 SER n 
1 407 TYR n 
1 408 TRP n 
1 409 PHE n 
1 410 PHE n 
1 411 VAL n 
1 412 GLY n 
1 413 LEU n 
1 414 SER n 
1 415 ILE n 
1 416 VAL n 
1 417 GLY n 
1 418 GLN n 
1 419 LEU n 
1 420 TYR n 
1 421 LEU n 
1 422 ARG n 
1 423 TRP n 
1 424 LYS n 
1 425 GLU n 
1 426 PRO n 
1 427 ASP n 
1 428 ARG n 
1 429 PRO n 
1 430 ARG n 
1 431 PRO n 
1 432 LEU n 
1 433 LYS n 
1 434 LEU n 
1 435 SER n 
1 436 VAL n 
1 437 PHE n 
1 438 PHE n 
1 439 PRO n 
1 440 ILE n 
1 441 VAL n 
1 442 PHE n 
1 443 CYS n 
1 444 LEU n 
1 445 CYS n 
1 446 THR n 
1 447 ILE n 
1 448 PHE n 
1 449 LEU n 
1 450 VAL n 
1 451 ALA n 
1 452 VAL n 
1 453 PRO n 
1 454 LEU n 
1 455 TYR n 
1 456 SER n 
1 457 ASP n 
1 458 THR n 
1 459 ILE n 
1 460 ASN n 
1 461 SER n 
1 462 LEU n 
1 463 ILE n 
1 464 GLY n 
1 465 ILE n 
1 466 ALA n 
1 467 ILE n 
1 468 ALA n 
1 469 LEU n 
1 470 SER n 
1 471 GLY n 
1 472 LEU n 
1 473 PRO n 
1 474 PHE n 
1 475 TYR n 
1 476 PHE n 
1 477 LEU n 
1 478 ILE n 
1 479 ILE n 
1 480 ARG n 
1 481 VAL n 
1 482 PRO n 
1 483 GLU n 
1 484 HIS n 
1 485 LYS n 
1 486 ARG n 
1 487 PRO n 
1 488 LEU n 
1 489 TYR n 
1 490 LEU n 
1 491 ARG n 
1 492 ARG n 
1 493 ILE n 
1 494 VAL n 
1 495 GLY n 
1 496 SER n 
1 497 ALA n 
1 498 THR n 
1 499 ARG n 
1 500 TYR n 
1 501 LEU n 
1 502 GLN n 
1 503 VAL n 
1 504 LEU n 
1 505 CYS n 
1 506 MET n 
1 507 SER n 
1 508 VAL n 
1 509 ALA n 
1 510 ALA n 
1 511 GLU n 
1 512 MET n 
1 513 ASP n 
1 514 LEU n 
1 515 GLU n 
1 516 ASP n 
1 517 GLY n 
1 518 GLY n 
1 519 GLU n 
1 520 MET n 
1 521 PRO n 
1 522 LYS n 
1 523 GLN n 
1 524 ARG n 
1 525 ASP n 
1 526 PRO n 
1 527 LYS n 
1 528 SER n 
1 529 ASN n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   529 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 SLC7A7 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ASP 1   -17 ?   ?   ?   A . n 
A 1 2   TYR 2   -16 ?   ?   ?   A . n 
A 1 3   LYS 3   -15 ?   ?   ?   A . n 
A 1 4   ASP 4   -14 ?   ?   ?   A . n 
A 1 5   ASP 5   -13 ?   ?   ?   A . n 
A 1 6   ASP 6   -12 ?   ?   ?   A . n 
A 1 7   ASP 7   -11 ?   ?   ?   A . n 
A 1 8   LYS 8   -10 ?   ?   ?   A . n 
A 1 9   SER 9   -9  ?   ?   ?   A . n 
A 1 10  GLY 10  -8  ?   ?   ?   A . n 
A 1 11  PRO 11  -7  ?   ?   ?   A . n 
A 1 12  ASP 12  -6  ?   ?   ?   A . n 
A 1 13  GLU 13  -5  ?   ?   ?   A . n 
A 1 14  VAL 14  -4  ?   ?   ?   A . n 
A 1 15  ASP 15  -3  ?   ?   ?   A . n 
A 1 16  ALA 16  -2  ?   ?   ?   A . n 
A 1 17  SER 17  -1  ?   ?   ?   A . n 
A 1 18  GLY 18  0   ?   ?   ?   A . n 
A 1 19  ARG 19  1   ?   ?   ?   A . n 
A 1 20  VAL 20  2   ?   ?   ?   A . n 
A 1 21  ASP 21  3   ?   ?   ?   A . n 
A 1 22  SER 22  4   ?   ?   ?   A . n 
A 1 23  THR 23  5   ?   ?   ?   A . n 
A 1 24  GLU 24  6   ?   ?   ?   A . n 
A 1 25  TYR 25  7   ?   ?   ?   A . n 
A 1 26  GLU 26  8   ?   ?   ?   A . n 
A 1 27  VAL 27  9   ?   ?   ?   A . n 
A 1 28  ALA 28  10  ?   ?   ?   A . n 
A 1 29  SER 29  11  ?   ?   ?   A . n 
A 1 30  GLN 30  12  ?   ?   ?   A . n 
A 1 31  PRO 31  13  ?   ?   ?   A . n 
A 1 32  GLU 32  14  ?   ?   ?   A . n 
A 1 33  VAL 33  15  ?   ?   ?   A . n 
A 1 34  GLU 34  16  ?   ?   ?   A . n 
A 1 35  THR 35  17  ?   ?   ?   A . n 
A 1 36  SER 36  18  ?   ?   ?   A . n 
A 1 37  PRO 37  19  ?   ?   ?   A . n 
A 1 38  LEU 38  20  ?   ?   ?   A . n 
A 1 39  GLY 39  21  ?   ?   ?   A . n 
A 1 40  ASP 40  22  ?   ?   ?   A . n 
A 1 41  GLY 41  23  ?   ?   ?   A . n 
A 1 42  ALA 42  24  ?   ?   ?   A . n 
A 1 43  SER 43  25  ?   ?   ?   A . n 
A 1 44  PRO 44  26  ?   ?   ?   A . n 
A 1 45  GLY 45  27  ?   ?   ?   A . n 
A 1 46  PRO 46  28  ?   ?   ?   A . n 
A 1 47  GLU 47  29  ?   ?   ?   A . n 
A 1 48  GLN 48  30  ?   ?   ?   A . n 
A 1 49  VAL 49  31  ?   ?   ?   A . n 
A 1 50  LYS 50  32  ?   ?   ?   A . n 
A 1 51  LEU 51  33  ?   ?   ?   A . n 
A 1 52  LYS 52  34  ?   ?   ?   A . n 
A 1 53  LYS 53  35  ?   ?   ?   A . n 
A 1 54  GLU 54  36  ?   ?   ?   A . n 
A 1 55  ILE 55  37  ?   ?   ?   A . n 
A 1 56  SER 56  38  38  SER SER A . n 
A 1 57  LEU 57  39  39  LEU LEU A . n 
A 1 58  LEU 58  40  40  LEU LEU A . n 
A 1 59  ASN 59  41  41  ASN ASN A . n 
A 1 60  GLY 60  42  42  GLY GLY A . n 
A 1 61  VAL 61  43  43  VAL VAL A . n 
A 1 62  CYS 62  44  44  CYS CYS A . n 
A 1 63  LEU 63  45  45  LEU LEU A . n 
A 1 64  ILE 64  46  46  ILE ILE A . n 
A 1 65  VAL 65  47  47  VAL VAL A . n 
A 1 66  GLY 66  48  48  GLY GLY A . n 
A 1 67  ASN 67  49  49  ASN ASN A . n 
A 1 68  MET 68  50  50  MET MET A . n 
A 1 69  ILE 69  51  51  ILE ILE A . n 
A 1 70  GLY 70  52  52  GLY GLY A . n 
A 1 71  SER 71  53  53  SER SER A . n 
A 1 72  GLY 72  54  54  GLY GLY A . n 
A 1 73  ILE 73  55  55  ILE ILE A . n 
A 1 74  PHE 74  56  56  PHE PHE A . n 
A 1 75  VAL 75  57  57  VAL VAL A . n 
A 1 76  SER 76  58  58  SER SER A . n 
A 1 77  PRO 77  59  59  PRO PRO A . n 
A 1 78  LYS 78  60  60  LYS LYS A . n 
A 1 79  GLY 79  61  61  GLY GLY A . n 
A 1 80  VAL 80  62  62  VAL VAL A . n 
A 1 81  LEU 81  63  63  LEU LEU A . n 
A 1 82  ILE 82  64  64  ILE ILE A . n 
A 1 83  TYR 83  65  65  TYR TYR A . n 
A 1 84  SER 84  66  66  SER SER A . n 
A 1 85  ALA 85  67  67  ALA ALA A . n 
A 1 86  SER 86  68  68  SER SER A . n 
A 1 87  PHE 87  69  69  PHE PHE A . n 
A 1 88  GLY 88  70  70  GLY GLY A . n 
A 1 89  LEU 89  71  71  LEU LEU A . n 
A 1 90  SER 90  72  72  SER SER A . n 
A 1 91  LEU 91  73  73  LEU LEU A . n 
A 1 92  VAL 92  74  74  VAL VAL A . n 
A 1 93  ILE 93  75  75  ILE ILE A . n 
A 1 94  TRP 94  76  76  TRP TRP A . n 
A 1 95  ALA 95  77  77  ALA ALA A . n 
A 1 96  VAL 96  78  78  VAL VAL A . n 
A 1 97  GLY 97  79  79  GLY GLY A . n 
A 1 98  GLY 98  80  80  GLY GLY A . n 
A 1 99  LEU 99  81  81  LEU LEU A . n 
A 1 100 PHE 100 82  82  PHE PHE A . n 
A 1 101 SER 101 83  83  SER SER A . n 
A 1 102 VAL 102 84  84  VAL VAL A . n 
A 1 103 PHE 103 85  85  PHE PHE A . n 
A 1 104 GLY 104 86  86  GLY GLY A . n 
A 1 105 ALA 105 87  87  ALA ALA A . n 
A 1 106 LEU 106 88  88  LEU LEU A . n 
A 1 107 CYS 107 89  89  CYS CYS A . n 
A 1 108 TYR 108 90  90  TYR TYR A . n 
A 1 109 ALA 109 91  91  ALA ALA A . n 
A 1 110 GLU 110 92  92  GLU GLU A . n 
A 1 111 LEU 111 93  93  LEU LEU A . n 
A 1 112 GLY 112 94  94  GLY GLY A . n 
A 1 113 THR 113 95  95  THR THR A . n 
A 1 114 THR 114 96  96  THR THR A . n 
A 1 115 ILE 115 97  97  ILE ILE A . n 
A 1 116 LYS 116 98  98  LYS LYS A . n 
A 1 117 LYS 117 99  99  LYS LYS A . n 
A 1 118 SER 118 100 100 SER SER A . n 
A 1 119 GLY 119 101 101 GLY GLY A . n 
A 1 120 ALA 120 102 102 ALA ALA A . n 
A 1 121 SER 121 103 103 SER SER A . n 
A 1 122 TYR 122 104 104 TYR TYR A . n 
A 1 123 ALA 123 105 105 ALA ALA A . n 
A 1 124 TYR 124 106 106 TYR TYR A . n 
A 1 125 ILE 125 107 107 ILE ILE A . n 
A 1 126 LEU 126 108 108 LEU LEU A . n 
A 1 127 GLU 127 109 109 GLU GLU A . n 
A 1 128 ALA 128 110 110 ALA ALA A . n 
A 1 129 PHE 129 111 111 PHE PHE A . n 
A 1 130 GLY 130 112 112 GLY GLY A . n 
A 1 131 GLY 131 113 113 GLY GLY A . n 
A 1 132 PHE 132 114 114 PHE PHE A . n 
A 1 133 LEU 133 115 115 LEU LEU A . n 
A 1 134 ALA 134 116 116 ALA ALA A . n 
A 1 135 PHE 135 117 117 PHE PHE A . n 
A 1 136 ILE 136 118 118 ILE ILE A . n 
A 1 137 ARG 137 119 119 ARG ARG A . n 
A 1 138 LEU 138 120 120 LEU LEU A . n 
A 1 139 TRP 139 121 121 TRP TRP A . n 
A 1 140 THR 140 122 122 THR THR A . n 
A 1 141 SER 141 123 123 SER SER A . n 
A 1 142 LEU 142 124 124 LEU LEU A . n 
A 1 143 LEU 143 125 125 LEU LEU A . n 
A 1 144 ILE 144 126 126 ILE ILE A . n 
A 1 145 ILE 145 127 127 ILE ILE A . n 
A 1 146 GLU 146 128 128 GLU GLU A . n 
A 1 147 PRO 147 129 129 PRO PRO A . n 
A 1 148 THR 148 130 130 THR THR A . n 
A 1 149 SER 149 131 131 SER SER A . n 
A 1 150 GLN 150 132 132 GLN GLN A . n 
A 1 151 ALA 151 133 133 ALA ALA A . n 
A 1 152 ILE 152 134 134 ILE ILE A . n 
A 1 153 ILE 153 135 135 ILE ILE A . n 
A 1 154 ALA 154 136 136 ALA ALA A . n 
A 1 155 ILE 155 137 137 ILE ILE A . n 
A 1 156 THR 156 138 138 THR THR A . n 
A 1 157 PHE 157 139 139 PHE PHE A . n 
A 1 158 ALA 158 140 140 ALA ALA A . n 
A 1 159 ASN 159 141 141 ASN ASN A . n 
A 1 160 TYR 160 142 142 TYR TYR A . n 
A 1 161 MET 161 143 143 MET MET A . n 
A 1 162 VAL 162 144 144 VAL VAL A . n 
A 1 163 GLN 163 145 145 GLN GLN A . n 
A 1 164 PRO 164 146 146 PRO PRO A . n 
A 1 165 LEU 165 147 147 LEU LEU A . n 
A 1 166 PHE 166 148 148 PHE PHE A . n 
A 1 167 PRO 167 149 149 PRO PRO A . n 
A 1 168 SER 168 150 150 SER SER A . n 
A 1 169 CYS 169 151 151 CYS CYS A . n 
A 1 170 PHE 170 152 152 PHE PHE A . n 
A 1 171 ALA 171 153 153 ALA ALA A . n 
A 1 172 PRO 172 154 154 PRO PRO A . n 
A 1 173 TYR 173 155 155 TYR TYR A . n 
A 1 174 ALA 174 156 156 ALA ALA A . n 
A 1 175 ALA 175 157 157 ALA ALA A . n 
A 1 176 SER 176 158 158 SER SER A . n 
A 1 177 ARG 177 159 159 ARG ARG A . n 
A 1 178 LEU 178 160 160 LEU LEU A . n 
A 1 179 LEU 179 161 161 LEU LEU A . n 
A 1 180 ALA 180 162 162 ALA ALA A . n 
A 1 181 ALA 181 163 163 ALA ALA A . n 
A 1 182 ALA 182 164 164 ALA ALA A . n 
A 1 183 CYS 183 165 165 CYS CYS A . n 
A 1 184 ILE 184 166 166 ILE ILE A . n 
A 1 185 CYS 185 167 167 CYS CYS A . n 
A 1 186 LEU 186 168 168 LEU LEU A . n 
A 1 187 LEU 187 169 169 LEU LEU A . n 
A 1 188 THR 188 170 170 THR THR A . n 
A 1 189 PHE 189 171 171 PHE PHE A . n 
A 1 190 ILE 190 172 172 ILE ILE A . n 
A 1 191 ASN 191 173 173 ASN ASN A . n 
A 1 192 CYS 192 174 174 CYS CYS A . n 
A 1 193 ALA 193 175 175 ALA ALA A . n 
A 1 194 TYR 194 176 176 TYR TYR A . n 
A 1 195 VAL 195 177 177 VAL VAL A . n 
A 1 196 LYS 196 178 178 LYS LYS A . n 
A 1 197 TRP 197 179 179 TRP TRP A . n 
A 1 198 GLY 198 180 180 GLY GLY A . n 
A 1 199 THR 199 181 181 THR THR A . n 
A 1 200 LEU 200 182 182 LEU LEU A . n 
A 1 201 VAL 201 183 183 VAL VAL A . n 
A 1 202 GLN 202 184 184 GLN GLN A . n 
A 1 203 ASP 203 185 185 ASP ASP A . n 
A 1 204 ILE 204 186 186 ILE ILE A . n 
A 1 205 PHE 205 187 187 PHE PHE A . n 
A 1 206 THR 206 188 188 THR THR A . n 
A 1 207 TYR 207 189 189 TYR TYR A . n 
A 1 208 ALA 208 190 190 ALA ALA A . n 
A 1 209 LYS 209 191 191 LYS LYS A . n 
A 1 210 VAL 210 192 192 VAL VAL A . n 
A 1 211 LEU 211 193 193 LEU LEU A . n 
A 1 212 ALA 212 194 194 ALA ALA A . n 
A 1 213 LEU 213 195 195 LEU LEU A . n 
A 1 214 ILE 214 196 196 ILE ILE A . n 
A 1 215 ALA 215 197 197 ALA ALA A . n 
A 1 216 VAL 216 198 198 VAL VAL A . n 
A 1 217 ILE 217 199 199 ILE ILE A . n 
A 1 218 VAL 218 200 200 VAL VAL A . n 
A 1 219 ALA 219 201 201 ALA ALA A . n 
A 1 220 GLY 220 202 202 GLY GLY A . n 
A 1 221 ILE 221 203 203 ILE ILE A . n 
A 1 222 VAL 222 204 204 VAL VAL A . n 
A 1 223 ARG 223 205 205 ARG ARG A . n 
A 1 224 LEU 224 206 206 LEU LEU A . n 
A 1 225 GLY 225 207 207 GLY GLY A . n 
A 1 226 GLN 226 208 208 GLN GLN A . n 
A 1 227 GLY 227 209 209 GLY GLY A . n 
A 1 228 ALA 228 210 210 ALA ALA A . n 
A 1 229 SER 229 211 211 SER SER A . n 
A 1 230 THR 230 212 212 THR THR A . n 
A 1 231 HIS 231 213 213 HIS HIS A . n 
A 1 232 PHE 232 214 214 PHE PHE A . n 
A 1 233 GLU 233 215 215 GLU GLU A . n 
A 1 234 ASN 234 216 216 ASN ASN A . n 
A 1 235 SER 235 217 217 SER SER A . n 
A 1 236 PHE 236 218 218 PHE PHE A . n 
A 1 237 GLU 237 219 219 GLU GLU A . n 
A 1 238 GLY 238 220 220 GLY GLY A . n 
A 1 239 SER 239 221 221 SER SER A . n 
A 1 240 SER 240 222 222 SER SER A . n 
A 1 241 PHE 241 223 223 PHE PHE A . n 
A 1 242 ALA 242 224 224 ALA ALA A . n 
A 1 243 VAL 243 225 225 VAL VAL A . n 
A 1 244 GLY 244 226 226 GLY GLY A . n 
A 1 245 ASP 245 227 227 ASP ASP A . n 
A 1 246 ILE 246 228 228 ILE ILE A . n 
A 1 247 ALA 247 229 229 ALA ALA A . n 
A 1 248 LEU 248 230 230 LEU LEU A . n 
A 1 249 ALA 249 231 231 ALA ALA A . n 
A 1 250 LEU 250 232 232 LEU LEU A . n 
A 1 251 TYR 251 233 233 TYR TYR A . n 
A 1 252 SER 252 234 234 SER SER A . n 
A 1 253 ALA 253 235 235 ALA ALA A . n 
A 1 254 LEU 254 236 236 LEU LEU A . n 
A 1 255 PHE 255 237 237 PHE PHE A . n 
A 1 256 SER 256 238 238 SER SER A . n 
A 1 257 TYR 257 239 239 TYR TYR A . n 
A 1 258 SER 258 240 240 SER SER A . n 
A 1 259 GLY 259 241 241 GLY GLY A . n 
A 1 260 TRP 260 242 242 TRP TRP A . n 
A 1 261 ASP 261 243 243 ASP ASP A . n 
A 1 262 THR 262 244 244 THR THR A . n 
A 1 263 LEU 263 245 245 LEU LEU A . n 
A 1 264 ASN 264 246 246 ASN ASN A . n 
A 1 265 TYR 265 247 247 TYR TYR A . n 
A 1 266 VAL 266 248 248 VAL VAL A . n 
A 1 267 THR 267 249 249 THR THR A . n 
A 1 268 GLU 268 250 250 GLU GLU A . n 
A 1 269 GLU 269 251 251 GLU GLU A . n 
A 1 270 ILE 270 252 252 ILE ILE A . n 
A 1 271 LYS 271 253 253 LYS LYS A . n 
A 1 272 ASN 272 254 254 ASN ASN A . n 
A 1 273 PRO 273 255 255 PRO PRO A . n 
A 1 274 GLU 274 256 256 GLU GLU A . n 
A 1 275 ARG 275 257 257 ARG ARG A . n 
A 1 276 ASN 276 258 258 ASN ASN A . n 
A 1 277 LEU 277 259 259 LEU LEU A . n 
A 1 278 PRO 278 260 260 PRO PRO A . n 
A 1 279 LEU 279 261 261 LEU LEU A . n 
A 1 280 SER 280 262 262 SER SER A . n 
A 1 281 ILE 281 263 263 ILE ILE A . n 
A 1 282 GLY 282 264 264 GLY GLY A . n 
A 1 283 ILE 283 265 265 ILE ILE A . n 
A 1 284 SER 284 266 266 SER SER A . n 
A 1 285 MET 285 267 267 MET MET A . n 
A 1 286 PRO 286 268 268 PRO PRO A . n 
A 1 287 ILE 287 269 269 ILE ILE A . n 
A 1 288 VAL 288 270 270 VAL VAL A . n 
A 1 289 THR 289 271 271 THR THR A . n 
A 1 290 ILE 290 272 272 ILE ILE A . n 
A 1 291 ILE 291 273 273 ILE ILE A . n 
A 1 292 TYR 292 274 274 TYR TYR A . n 
A 1 293 ILE 293 275 275 ILE ILE A . n 
A 1 294 LEU 294 276 276 LEU LEU A . n 
A 1 295 THR 295 277 277 THR THR A . n 
A 1 296 ASN 296 278 278 ASN ASN A . n 
A 1 297 VAL 297 279 279 VAL VAL A . n 
A 1 298 ALA 298 280 280 ALA ALA A . n 
A 1 299 TYR 299 281 281 TYR TYR A . n 
A 1 300 TYR 300 282 282 TYR TYR A . n 
A 1 301 THR 301 283 283 THR THR A . n 
A 1 302 VAL 302 284 284 VAL VAL A . n 
A 1 303 LEU 303 285 285 LEU LEU A . n 
A 1 304 ASP 304 286 286 ASP ASP A . n 
A 1 305 MET 305 287 287 MET MET A . n 
A 1 306 ARG 306 288 288 ARG ARG A . n 
A 1 307 ASP 307 289 289 ASP ASP A . n 
A 1 308 ILE 308 290 290 ILE ILE A . n 
A 1 309 LEU 309 291 291 LEU LEU A . n 
A 1 310 ALA 310 292 292 ALA ALA A . n 
A 1 311 SER 311 293 293 SER SER A . n 
A 1 312 ASP 312 294 294 ASP ASP A . n 
A 1 313 ALA 313 295 295 ALA ALA A . n 
A 1 314 VAL 314 296 296 VAL VAL A . n 
A 1 315 ALA 315 297 297 ALA ALA A . n 
A 1 316 VAL 316 298 298 VAL VAL A . n 
A 1 317 THR 317 299 299 THR THR A . n 
A 1 318 PHE 318 300 300 PHE PHE A . n 
A 1 319 ALA 319 301 301 ALA ALA A . n 
A 1 320 ASP 320 302 302 ASP ASP A . n 
A 1 321 GLN 321 303 303 GLN GLN A . n 
A 1 322 ILE 322 304 304 ILE ILE A . n 
A 1 323 PHE 323 305 305 PHE PHE A . n 
A 1 324 GLY 324 306 306 GLY GLY A . n 
A 1 325 ILE 325 307 307 ILE ILE A . n 
A 1 326 PHE 326 308 308 PHE PHE A . n 
A 1 327 ASN 327 309 309 ASN ASN A . n 
A 1 328 TRP 328 310 310 TRP TRP A . n 
A 1 329 ILE 329 311 311 ILE ILE A . n 
A 1 330 ILE 330 312 312 ILE ILE A . n 
A 1 331 PRO 331 313 313 PRO PRO A . n 
A 1 332 LEU 332 314 314 LEU LEU A . n 
A 1 333 SER 333 315 315 SER SER A . n 
A 1 334 VAL 334 316 316 VAL VAL A . n 
A 1 335 ALA 335 317 317 ALA ALA A . n 
A 1 336 LEU 336 318 318 LEU LEU A . n 
A 1 337 SER 337 319 319 SER SER A . n 
A 1 338 CYS 338 320 320 CYS CYS A . n 
A 1 339 PHE 339 321 321 PHE PHE A . n 
A 1 340 GLY 340 322 322 GLY GLY A . n 
A 1 341 GLY 341 323 323 GLY GLY A . n 
A 1 342 LEU 342 324 324 LEU LEU A . n 
A 1 343 ASN 343 325 325 ASN ASN A . n 
A 1 344 ALA 344 326 326 ALA ALA A . n 
A 1 345 SER 345 327 327 SER SER A . n 
A 1 346 ILE 346 328 328 ILE ILE A . n 
A 1 347 VAL 347 329 329 VAL VAL A . n 
A 1 348 ALA 348 330 330 ALA ALA A . n 
A 1 349 ALA 349 331 331 ALA ALA A . n 
A 1 350 SER 350 332 332 SER SER A . n 
A 1 351 ARG 351 333 333 ARG ARG A . n 
A 1 352 LEU 352 334 334 LEU LEU A . n 
A 1 353 PHE 353 335 335 PHE PHE A . n 
A 1 354 PHE 354 336 336 PHE PHE A . n 
A 1 355 VAL 355 337 337 VAL VAL A . n 
A 1 356 GLY 356 338 338 GLY GLY A . n 
A 1 357 SER 357 339 339 SER SER A . n 
A 1 358 ARG 358 340 340 ARG ARG A . n 
A 1 359 GLU 359 341 341 GLU GLU A . n 
A 1 360 GLY 360 342 342 GLY GLY A . n 
A 1 361 HIS 361 343 343 HIS HIS A . n 
A 1 362 LEU 362 344 344 LEU LEU A . n 
A 1 363 PRO 363 345 345 PRO PRO A . n 
A 1 364 ASP 364 346 346 ASP ASP A . n 
A 1 365 ALA 365 347 347 ALA ALA A . n 
A 1 366 ILE 366 348 348 ILE ILE A . n 
A 1 367 CYS 367 349 349 CYS CYS A . n 
A 1 368 MET 368 350 350 MET MET A . n 
A 1 369 ILE 369 351 351 ILE ILE A . n 
A 1 370 HIS 370 352 352 HIS HIS A . n 
A 1 371 VAL 371 353 353 VAL VAL A . n 
A 1 372 GLU 372 354 354 GLU GLU A . n 
A 1 373 ARG 373 355 355 ARG ARG A . n 
A 1 374 PHE 374 356 356 PHE PHE A . n 
A 1 375 THR 375 357 357 THR THR A . n 
A 1 376 PRO 376 358 358 PRO PRO A . n 
A 1 377 VAL 377 359 359 VAL VAL A . n 
A 1 378 PRO 378 360 360 PRO PRO A . n 
A 1 379 SER 379 361 361 SER SER A . n 
A 1 380 LEU 380 362 362 LEU LEU A . n 
A 1 381 LEU 381 363 363 LEU LEU A . n 
A 1 382 PHE 382 364 364 PHE PHE A . n 
A 1 383 ASN 383 365 365 ASN ASN A . n 
A 1 384 GLY 384 366 366 GLY GLY A . n 
A 1 385 ILE 385 367 367 ILE ILE A . n 
A 1 386 MET 386 368 368 MET MET A . n 
A 1 387 ALA 387 369 369 ALA ALA A . n 
A 1 388 LEU 388 370 370 LEU LEU A . n 
A 1 389 ILE 389 371 371 ILE ILE A . n 
A 1 390 TYR 390 372 372 TYR TYR A . n 
A 1 391 LEU 391 373 373 LEU LEU A . n 
A 1 392 CYS 392 374 374 CYS CYS A . n 
A 1 393 VAL 393 375 375 VAL VAL A . n 
A 1 394 GLU 394 376 376 GLU GLU A . n 
A 1 395 ASP 395 377 377 ASP ASP A . n 
A 1 396 ILE 396 378 378 ILE ILE A . n 
A 1 397 PHE 397 379 379 PHE PHE A . n 
A 1 398 GLN 398 380 380 GLN GLN A . n 
A 1 399 LEU 399 381 381 LEU LEU A . n 
A 1 400 ILE 400 382 382 ILE ILE A . n 
A 1 401 ASN 401 383 383 ASN ASN A . n 
A 1 402 TYR 402 384 384 TYR TYR A . n 
A 1 403 TYR 403 385 385 TYR TYR A . n 
A 1 404 SER 404 386 386 SER SER A . n 
A 1 405 PHE 405 387 387 PHE PHE A . n 
A 1 406 SER 406 388 388 SER SER A . n 
A 1 407 TYR 407 389 389 TYR TYR A . n 
A 1 408 TRP 408 390 390 TRP TRP A . n 
A 1 409 PHE 409 391 391 PHE PHE A . n 
A 1 410 PHE 410 392 392 PHE PHE A . n 
A 1 411 VAL 411 393 393 VAL VAL A . n 
A 1 412 GLY 412 394 394 GLY GLY A . n 
A 1 413 LEU 413 395 395 LEU LEU A . n 
A 1 414 SER 414 396 396 SER SER A . n 
A 1 415 ILE 415 397 397 ILE ILE A . n 
A 1 416 VAL 416 398 398 VAL VAL A . n 
A 1 417 GLY 417 399 399 GLY GLY A . n 
A 1 418 GLN 418 400 400 GLN GLN A . n 
A 1 419 LEU 419 401 401 LEU LEU A . n 
A 1 420 TYR 420 402 402 TYR TYR A . n 
A 1 421 LEU 421 403 403 LEU LEU A . n 
A 1 422 ARG 422 404 404 ARG ARG A . n 
A 1 423 TRP 423 405 405 TRP TRP A . n 
A 1 424 LYS 424 406 406 LYS LYS A . n 
A 1 425 GLU 425 407 407 GLU GLU A . n 
A 1 426 PRO 426 408 408 PRO PRO A . n 
A 1 427 ASP 427 409 409 ASP ASP A . n 
A 1 428 ARG 428 410 410 ARG ARG A . n 
A 1 429 PRO 429 411 411 PRO PRO A . n 
A 1 430 ARG 430 412 412 ARG ARG A . n 
A 1 431 PRO 431 413 413 PRO PRO A . n 
A 1 432 LEU 432 414 414 LEU LEU A . n 
A 1 433 LYS 433 415 415 LYS LYS A . n 
A 1 434 LEU 434 416 416 LEU LEU A . n 
A 1 435 SER 435 417 417 SER SER A . n 
A 1 436 VAL 436 418 418 VAL VAL A . n 
A 1 437 PHE 437 419 419 PHE PHE A . n 
A 1 438 PHE 438 420 420 PHE PHE A . n 
A 1 439 PRO 439 421 421 PRO PRO A . n 
A 1 440 ILE 440 422 422 ILE ILE A . n 
A 1 441 VAL 441 423 423 VAL VAL A . n 
A 1 442 PHE 442 424 424 PHE PHE A . n 
A 1 443 CYS 443 425 425 CYS CYS A . n 
A 1 444 LEU 444 426 426 LEU LEU A . n 
A 1 445 CYS 445 427 427 CYS CYS A . n 
A 1 446 THR 446 428 428 THR THR A . n 
A 1 447 ILE 447 429 429 ILE ILE A . n 
A 1 448 PHE 448 430 430 PHE PHE A . n 
A 1 449 LEU 449 431 431 LEU LEU A . n 
A 1 450 VAL 450 432 432 VAL VAL A . n 
A 1 451 ALA 451 433 433 ALA ALA A . n 
A 1 452 VAL 452 434 434 VAL VAL A . n 
A 1 453 PRO 453 435 435 PRO PRO A . n 
A 1 454 LEU 454 436 436 LEU LEU A . n 
A 1 455 TYR 455 437 437 TYR TYR A . n 
A 1 456 SER 456 438 438 SER SER A . n 
A 1 457 ASP 457 439 439 ASP ASP A . n 
A 1 458 THR 458 440 440 THR THR A . n 
A 1 459 ILE 459 441 441 ILE ILE A . n 
A 1 460 ASN 460 442 442 ASN ASN A . n 
A 1 461 SER 461 443 443 SER SER A . n 
A 1 462 LEU 462 444 444 LEU LEU A . n 
A 1 463 ILE 463 445 445 ILE ILE A . n 
A 1 464 GLY 464 446 446 GLY GLY A . n 
A 1 465 ILE 465 447 447 ILE ILE A . n 
A 1 466 ALA 466 448 448 ALA ALA A . n 
A 1 467 ILE 467 449 449 ILE ILE A . n 
A 1 468 ALA 468 450 450 ALA ALA A . n 
A 1 469 LEU 469 451 451 LEU LEU A . n 
A 1 470 SER 470 452 452 SER SER A . n 
A 1 471 GLY 471 453 453 GLY GLY A . n 
A 1 472 LEU 472 454 454 LEU LEU A . n 
A 1 473 PRO 473 455 455 PRO PRO A . n 
A 1 474 PHE 474 456 456 PHE PHE A . n 
A 1 475 TYR 475 457 457 TYR TYR A . n 
A 1 476 PHE 476 458 458 PHE PHE A . n 
A 1 477 LEU 477 459 459 LEU LEU A . n 
A 1 478 ILE 478 460 460 ILE ILE A . n 
A 1 479 ILE 479 461 461 ILE ILE A . n 
A 1 480 ARG 480 462 462 ARG ARG A . n 
A 1 481 VAL 481 463 463 VAL VAL A . n 
A 1 482 PRO 482 464 464 PRO PRO A . n 
A 1 483 GLU 483 465 465 GLU GLU A . n 
A 1 484 HIS 484 466 466 HIS HIS A . n 
A 1 485 LYS 485 467 467 LYS LYS A . n 
A 1 486 ARG 486 468 468 ARG ARG A . n 
A 1 487 PRO 487 469 469 PRO PRO A . n 
A 1 488 LEU 488 470 470 LEU LEU A . n 
A 1 489 TYR 489 471 471 TYR TYR A . n 
A 1 490 LEU 490 472 472 LEU LEU A . n 
A 1 491 ARG 491 473 473 ARG ARG A . n 
A 1 492 ARG 492 474 474 ARG ARG A . n 
A 1 493 ILE 493 475 475 ILE ILE A . n 
A 1 494 VAL 494 476 476 VAL VAL A . n 
A 1 495 GLY 495 477 477 GLY GLY A . n 
A 1 496 SER 496 478 478 SER SER A . n 
A 1 497 ALA 497 479 479 ALA ALA A . n 
A 1 498 THR 498 480 480 THR THR A . n 
A 1 499 ARG 499 481 481 ARG ARG A . n 
A 1 500 TYR 500 482 482 TYR TYR A . n 
A 1 501 LEU 501 483 483 LEU LEU A . n 
A 1 502 GLN 502 484 484 GLN GLN A . n 
A 1 503 VAL 503 485 485 VAL VAL A . n 
A 1 504 LEU 504 486 486 LEU LEU A . n 
A 1 505 CYS 505 487 487 CYS CYS A . n 
A 1 506 MET 506 488 488 MET MET A . n 
A 1 507 SER 507 489 489 SER SER A . n 
A 1 508 VAL 508 490 490 VAL VAL A . n 
A 1 509 ALA 509 491 491 ALA ALA A . n 
A 1 510 ALA 510 492 492 ALA ALA A . n 
A 1 511 GLU 511 493 ?   ?   ?   A . n 
A 1 512 MET 512 494 ?   ?   ?   A . n 
A 1 513 ASP 513 495 ?   ?   ?   A . n 
A 1 514 LEU 514 496 ?   ?   ?   A . n 
A 1 515 GLU 515 497 ?   ?   ?   A . n 
A 1 516 ASP 516 498 ?   ?   ?   A . n 
A 1 517 GLY 517 499 ?   ?   ?   A . n 
A 1 518 GLY 518 500 ?   ?   ?   A . n 
A 1 519 GLU 519 501 ?   ?   ?   A . n 
A 1 520 MET 520 502 ?   ?   ?   A . n 
A 1 521 PRO 521 503 ?   ?   ?   A . n 
A 1 522 LYS 522 504 ?   ?   ?   A . n 
A 1 523 GLN 523 505 ?   ?   ?   A . n 
A 1 524 ARG 524 506 ?   ?   ?   A . n 
A 1 525 ASP 525 507 ?   ?   ?   A . n 
A 1 526 PRO 526 508 ?   ?   ?   A . n 
A 1 527 LYS 527 509 ?   ?   ?   A . n 
A 1 528 SER 528 510 ?   ?   ?   A . n 
A 1 529 ASN 529 511 ?   ?   ?   A . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9KH5 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9KH5 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9KH5 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9KH5 
_struct.title                        'Structure of y+LAT1' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9KH5 
_struct_keywords.text            'membrane protein, amino acid' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
_struct_asym.id                            A 
_struct_asym.pdbx_blank_PDB_chainid_flag   N 
_struct_asym.pdbx_modified                 N 
_struct_asym.entity_id                     1 
_struct_asym.details                       ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    YLAT1_HUMAN 
_struct_ref.pdbx_db_accession          Q9UM01 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;VDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGL
FSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLL
AAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSG
WDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCF
GGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQL
YLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATR
YLQVLCMSVAAEMDLEDGGEMPKQRDPKSN
;
_struct_ref.pdbx_align_begin           2 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9KH5 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 20 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 529 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             Q9UM01 
_struct_ref_seq.db_align_beg                  2 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  511 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       2 
_struct_ref_seq.pdbx_auth_seq_align_end       511 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9KH5 ASP A 1  ? UNP Q9UM01 ? ? 'expression tag' -17 1  
1 9KH5 TYR A 2  ? UNP Q9UM01 ? ? 'expression tag' -16 2  
1 9KH5 LYS A 3  ? UNP Q9UM01 ? ? 'expression tag' -15 3  
1 9KH5 ASP A 4  ? UNP Q9UM01 ? ? 'expression tag' -14 4  
1 9KH5 ASP A 5  ? UNP Q9UM01 ? ? 'expression tag' -13 5  
1 9KH5 ASP A 6  ? UNP Q9UM01 ? ? 'expression tag' -12 6  
1 9KH5 ASP A 7  ? UNP Q9UM01 ? ? 'expression tag' -11 7  
1 9KH5 LYS A 8  ? UNP Q9UM01 ? ? 'expression tag' -10 8  
1 9KH5 SER A 9  ? UNP Q9UM01 ? ? 'expression tag' -9  9  
1 9KH5 GLY A 10 ? UNP Q9UM01 ? ? 'expression tag' -8  10 
1 9KH5 PRO A 11 ? UNP Q9UM01 ? ? 'expression tag' -7  11 
1 9KH5 ASP A 12 ? UNP Q9UM01 ? ? 'expression tag' -6  12 
1 9KH5 GLU A 13 ? UNP Q9UM01 ? ? 'expression tag' -5  13 
1 9KH5 VAL A 14 ? UNP Q9UM01 ? ? 'expression tag' -4  14 
1 9KH5 ASP A 15 ? UNP Q9UM01 ? ? 'expression tag' -3  15 
1 9KH5 ALA A 16 ? UNP Q9UM01 ? ? 'expression tag' -2  16 
1 9KH5 SER A 17 ? UNP Q9UM01 ? ? 'expression tag' -1  17 
1 9KH5 GLY A 18 ? UNP Q9UM01 ? ? 'expression tag' 0   18 
1 9KH5 ARG A 19 ? UNP Q9UM01 ? ? 'expression tag' 1   19 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 56  ? GLY A 66  ? SER A 38  GLY A 48  1 ? 11 
HELX_P HELX_P2  AA2 SER A 71  ? PHE A 74  ? SER A 53  PHE A 56  5 ? 4  
HELX_P HELX_P3  AA3 VAL A 75  ? ALA A 85  ? VAL A 57  ALA A 67  1 ? 11 
HELX_P HELX_P4  AA4 SER A 86  ? ILE A 115 ? SER A 68  ILE A 97  1 ? 30 
HELX_P HELX_P5  AA5 TYR A 122 ? GLY A 130 ? TYR A 104 GLY A 112 1 ? 9  
HELX_P HELX_P6  AA6 GLY A 131 ? ILE A 144 ? GLY A 113 ILE A 126 1 ? 14 
HELX_P HELX_P7  AA7 ILE A 144 ? GLN A 163 ? ILE A 126 GLN A 145 1 ? 20 
HELX_P HELX_P8  AA8 PRO A 172 ? CYS A 192 ? PRO A 154 CYS A 174 1 ? 21 
HELX_P HELX_P9  AA9 VAL A 195 ? GLY A 227 ? VAL A 177 GLY A 209 1 ? 33 
HELX_P HELX_P10 AB1 GLY A 244 ? SER A 258 ? GLY A 226 SER A 240 1 ? 15 
HELX_P HELX_P11 AB2 ARG A 275 ? LEU A 303 ? ARG A 257 LEU A 285 1 ? 29 
HELX_P HELX_P12 AB3 ASP A 304 ? SER A 311 ? ASP A 286 SER A 293 1 ? 8  
HELX_P HELX_P13 AB4 ALA A 313 ? PHE A 323 ? ALA A 295 PHE A 305 1 ? 11 
HELX_P HELX_P14 AB5 ILE A 329 ? ARG A 358 ? ILE A 311 ARG A 340 1 ? 30 
HELX_P HELX_P15 AB6 PRO A 376 ? CYS A 392 ? PRO A 358 CYS A 374 1 ? 17 
HELX_P HELX_P16 AB7 ASP A 395 ? LYS A 424 ? ASP A 377 LYS A 406 1 ? 30 
HELX_P HELX_P17 AB8 VAL A 436 ? VAL A 452 ? VAL A 418 VAL A 434 1 ? 17 
HELX_P HELX_P18 AB9 ASP A 457 ? ILE A 479 ? ASP A 439 ILE A 461 1 ? 23 
HELX_P HELX_P19 AC1 HIS A 484 ? MET A 506 ? HIS A 466 MET A 488 1 ? 23 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_sheet.id               AA1 
_struct_sheet.type             ? 
_struct_sheet.number_strands   2 
_struct_sheet.details          ? 
# 
_struct_sheet_order.sheet_id     AA1 
_struct_sheet_order.range_id_1   1 
_struct_sheet_order.range_id_2   2 
_struct_sheet_order.offset       ? 
_struct_sheet_order.sense        anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 369 ? HIS A 370 ? ILE A 351 HIS A 352 
AA1 2 SER A 507 ? VAL A 508 ? SER A 489 VAL A 490 
# 
_pdbx_struct_sheet_hbond.sheet_id                AA1 
_pdbx_struct_sheet_hbond.range_id_1              1 
_pdbx_struct_sheet_hbond.range_id_2              2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id   N 
_pdbx_struct_sheet_hbond.range_1_label_comp_id   ILE 
_pdbx_struct_sheet_hbond.range_1_label_asym_id   A 
_pdbx_struct_sheet_hbond.range_1_label_seq_id    369 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id    N 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id    ILE 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id    A 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id     351 
_pdbx_struct_sheet_hbond.range_2_label_atom_id   O 
_pdbx_struct_sheet_hbond.range_2_label_comp_id   VAL 
_pdbx_struct_sheet_hbond.range_2_label_asym_id   A 
_pdbx_struct_sheet_hbond.range_2_label_seq_id    508 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id    O 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id    VAL 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id    A 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id     490 
# 
_pdbx_entry_details.entry_id                   9KH5 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 VAL A 57  ? ? -127.34 -51.41  
2  1 ALA A 67  ? ? 65.59   -7.59   
3  1 SER A 103 ? ? 69.71   -10.06  
4  1 TYR A 104 ? ? -112.08 -79.83  
5  1 ILE A 126 ? ? -123.78 -62.69  
6  1 SER A 150 ? ? 69.25   -1.44   
7  1 GLU A 215 ? ? 39.91   51.25   
8  1 ASN A 216 ? ? -161.78 108.74  
9  1 SER A 217 ? ? -114.33 -93.27  
10 1 PHE A 218 ? ? 66.58   -11.57  
11 1 GLU A 256 ? ? 49.11   -125.10 
12 1 THR A 283 ? ? -68.95  6.45    
13 1 PHE A 305 ? ? -122.61 -168.28 
14 1 ILE A 307 ? ? -90.74  -61.89  
15 1 PHE A 308 ? ? 71.56   -15.16  
16 1 ASN A 309 ? ? -130.04 -42.16  
17 1 ILE A 311 ? ? -126.02 -65.90  
18 1 ARG A 340 ? ? -58.86  -8.07   
19 1 LEU A 344 ? ? 57.42   74.24   
20 1 PRO A 345 ? ? -38.75  136.52  
21 1 ASP A 346 ? ? -55.83  -9.44   
22 1 CYS A 349 ? ? 64.64   61.55   
23 1 PRO A 408 ? ? -79.54  -169.08 
24 1 ARG A 462 ? ? -111.84 63.74   
25 1 LYS A 467 ? ? 58.07   -150.64 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9KH5 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9KH5 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.74 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               276483 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Cryo-EM structure of y+LAT1 in an apo conformation' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9KH5 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               OTHER 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             5000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9KH5 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9KH5 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A ASP -17 ? A ASP 1   
2  1 Y 1 A TYR -16 ? A TYR 2   
3  1 Y 1 A LYS -15 ? A LYS 3   
4  1 Y 1 A ASP -14 ? A ASP 4   
5  1 Y 1 A ASP -13 ? A ASP 5   
6  1 Y 1 A ASP -12 ? A ASP 6   
7  1 Y 1 A ASP -11 ? A ASP 7   
8  1 Y 1 A LYS -10 ? A LYS 8   
9  1 Y 1 A SER -9  ? A SER 9   
10 1 Y 1 A GLY -8  ? A GLY 10  
11 1 Y 1 A PRO -7  ? A PRO 11  
12 1 Y 1 A ASP -6  ? A ASP 12  
13 1 Y 1 A GLU -5  ? A GLU 13  
14 1 Y 1 A VAL -4  ? A VAL 14  
15 1 Y 1 A ASP -3  ? A ASP 15  
16 1 Y 1 A ALA -2  ? A ALA 16  
17 1 Y 1 A SER -1  ? A SER 17  
18 1 Y 1 A GLY 0   ? A GLY 18  
19 1 Y 1 A ARG 1   ? A ARG 19  
20 1 Y 1 A VAL 2   ? A VAL 20  
21 1 Y 1 A ASP 3   ? A ASP 21  
22 1 Y 1 A SER 4   ? A SER 22  
23 1 Y 1 A THR 5   ? A THR 23  
24 1 Y 1 A GLU 6   ? A GLU 24  
25 1 Y 1 A TYR 7   ? A TYR 25  
26 1 Y 1 A GLU 8   ? A GLU 26  
27 1 Y 1 A VAL 9   ? A VAL 27  
28 1 Y 1 A ALA 10  ? A ALA 28  
29 1 Y 1 A SER 11  ? A SER 29  
30 1 Y 1 A GLN 12  ? A GLN 30  
31 1 Y 1 A PRO 13  ? A PRO 31  
32 1 Y 1 A GLU 14  ? A GLU 32  
33 1 Y 1 A VAL 15  ? A VAL 33  
34 1 Y 1 A GLU 16  ? A GLU 34  
35 1 Y 1 A THR 17  ? A THR 35  
36 1 Y 1 A SER 18  ? A SER 36  
37 1 Y 1 A PRO 19  ? A PRO 37  
38 1 Y 1 A LEU 20  ? A LEU 38  
39 1 Y 1 A GLY 21  ? A GLY 39  
40 1 Y 1 A ASP 22  ? A ASP 40  
41 1 Y 1 A GLY 23  ? A GLY 41  
42 1 Y 1 A ALA 24  ? A ALA 42  
43 1 Y 1 A SER 25  ? A SER 43  
44 1 Y 1 A PRO 26  ? A PRO 44  
45 1 Y 1 A GLY 27  ? A GLY 45  
46 1 Y 1 A PRO 28  ? A PRO 46  
47 1 Y 1 A GLU 29  ? A GLU 47  
48 1 Y 1 A GLN 30  ? A GLN 48  
49 1 Y 1 A VAL 31  ? A VAL 49  
50 1 Y 1 A LYS 32  ? A LYS 50  
51 1 Y 1 A LEU 33  ? A LEU 51  
52 1 Y 1 A LYS 34  ? A LYS 52  
53 1 Y 1 A LYS 35  ? A LYS 53  
54 1 Y 1 A GLU 36  ? A GLU 54  
55 1 Y 1 A ILE 37  ? A ILE 55  
56 1 Y 1 A GLU 493 ? A GLU 511 
57 1 Y 1 A MET 494 ? A MET 512 
58 1 Y 1 A ASP 495 ? A ASP 513 
59 1 Y 1 A LEU 496 ? A LEU 514 
60 1 Y 1 A GLU 497 ? A GLU 515 
61 1 Y 1 A ASP 498 ? A ASP 516 
62 1 Y 1 A GLY 499 ? A GLY 517 
63 1 Y 1 A GLY 500 ? A GLY 518 
64 1 Y 1 A GLU 501 ? A GLU 519 
65 1 Y 1 A MET 502 ? A MET 520 
66 1 Y 1 A PRO 503 ? A PRO 521 
67 1 Y 1 A LYS 504 ? A LYS 522 
68 1 Y 1 A GLN 505 ? A GLN 523 
69 1 Y 1 A ARG 506 ? A ARG 524 
70 1 Y 1 A ASP 507 ? A ASP 525 
71 1 Y 1 A PRO 508 ? A PRO 526 
72 1 Y 1 A LYS 509 ? A LYS 527 
73 1 Y 1 A SER 510 ? A SER 528 
74 1 Y 1 A ASN 511 ? A ASN 529 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-11-09 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9KH5 
_em_admin.last_update        2025-04-02 
_em_admin.map_release_date   2025-04-02 
_em_admin.title              'Structure of y+LAT1' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9KH5 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . SER A 1 56  ? 136.441 88.505  110.531 1.00 222.68 ?  38  SER A N   1 
ATOM 2    C CA  . SER A 1 56  ? 136.662 89.036  109.195 1.00 222.68 ?  38  SER A CA  1 
ATOM 3    C C   . SER A 1 56  ? 135.370 89.590  108.620 1.00 222.68 ?  38  SER A C   1 
ATOM 4    O O   . SER A 1 56  ? 134.526 90.099  109.356 1.00 222.68 ?  38  SER A O   1 
ATOM 5    C CB  . SER A 1 56  ? 137.224 87.960  108.270 1.00 222.68 ?  38  SER A CB  1 
ATOM 6    O OG  . SER A 1 56  ? 136.180 87.264  107.619 1.00 222.68 ?  38  SER A OG  1 
ATOM 7    N N   . LEU A 1 57  ? 135.219 89.478  107.298 1.00 214.86 ?  39  LEU A N   1 
ATOM 8    C CA  . LEU A 1 57  ? 134.041 90.036  106.644 1.00 214.86 ?  39  LEU A CA  1 
ATOM 9    C C   . LEU A 1 57  ? 132.758 89.446  107.207 1.00 214.86 ?  39  LEU A C   1 
ATOM 10   O O   . LEU A 1 57  ? 131.726 90.125  107.237 1.00 214.86 ?  39  LEU A O   1 
ATOM 11   C CB  . LEU A 1 57  ? 134.105 89.817  105.134 1.00 214.86 ?  39  LEU A CB  1 
ATOM 12   C CG  . LEU A 1 57  ? 133.875 88.411  104.591 1.00 214.86 ?  39  LEU A CG  1 
ATOM 13   C CD1 . LEU A 1 57  ? 133.460 88.504  103.148 1.00 214.86 ?  39  LEU A CD1 1 
ATOM 14   C CD2 . LEU A 1 57  ? 135.132 87.578  104.706 1.00 214.86 ?  39  LEU A CD2 1 
ATOM 15   N N   . LEU A 1 58  ? 132.803 88.195  107.667 1.00 222.79 ?  40  LEU A N   1 
ATOM 16   C CA  . LEU A 1 58  ? 131.641 87.627  108.338 1.00 222.79 ?  40  LEU A CA  1 
ATOM 17   C C   . LEU A 1 58  ? 131.263 88.452  109.553 1.00 222.79 ?  40  LEU A C   1 
ATOM 18   O O   . LEU A 1 58  ? 130.083 88.539  109.906 1.00 222.79 ?  40  LEU A O   1 
ATOM 19   C CB  . LEU A 1 58  ? 131.914 86.182  108.750 1.00 222.79 ?  40  LEU A CB  1 
ATOM 20   C CG  . LEU A 1 58  ? 132.748 85.932  110.009 1.00 222.79 ?  40  LEU A CG  1 
ATOM 21   C CD1 . LEU A 1 58  ? 132.611 84.485  110.443 1.00 222.79 ?  40  LEU A CD1 1 
ATOM 22   C CD2 . LEU A 1 58  ? 134.204 86.289  109.810 1.00 222.79 ?  40  LEU A CD2 1 
ATOM 23   N N   . ASN A 1 59  ? 132.243 89.069  110.196 1.00 219.56 ?  41  ASN A N   1 
ATOM 24   C CA  . ASN A 1 59  ? 131.977 89.921  111.338 1.00 219.56 ?  41  ASN A CA  1 
ATOM 25   C C   . ASN A 1 59  ? 131.747 91.367  110.941 1.00 219.56 ?  41  ASN A C   1 
ATOM 26   O O   . ASN A 1 59  ? 131.431 92.185  111.807 1.00 219.56 ?  41  ASN A O   1 
ATOM 27   C CB  . ASN A 1 59  ? 133.137 89.830  112.325 1.00 219.56 ?  41  ASN A CB  1 
ATOM 28   C CG  . ASN A 1 59  ? 133.396 88.412  112.776 1.00 219.56 ?  41  ASN A CG  1 
ATOM 29   O OD1 . ASN A 1 59  ? 132.466 87.625  112.939 1.00 219.56 ?  41  ASN A OD1 1 
ATOM 30   N ND2 . ASN A 1 59  ? 134.663 88.074  112.976 1.00 219.56 ?  41  ASN A ND2 1 
ATOM 31   N N   . GLY A 1 60  ? 131.898 91.701  109.668 1.00 203.38 ?  42  GLY A N   1 
ATOM 32   C CA  . GLY A 1 60  ? 131.754 93.079  109.254 1.00 203.38 ?  42  GLY A CA  1 
ATOM 33   C C   . GLY A 1 60  ? 130.356 93.417  108.795 1.00 203.38 ?  42  GLY A C   1 
ATOM 34   O O   . GLY A 1 60  ? 129.921 94.569  108.896 1.00 203.38 ?  42  GLY A O   1 
ATOM 35   N N   . VAL A 1 61  ? 129.642 92.414  108.285 1.00 199.59 ?  43  VAL A N   1 
ATOM 36   C CA  . VAL A 1 61  ? 128.317 92.664  107.729 1.00 199.59 ?  43  VAL A CA  1 
ATOM 37   C C   . VAL A 1 61  ? 127.381 93.198  108.803 1.00 199.59 ?  43  VAL A C   1 
ATOM 38   O O   . VAL A 1 61  ? 126.648 94.169  108.583 1.00 199.59 ?  43  VAL A O   1 
ATOM 39   C CB  . VAL A 1 61  ? 127.772 91.392  107.050 1.00 199.59 ?  43  VAL A CB  1 
ATOM 40   C CG1 . VAL A 1 61  ? 128.796 90.850  106.077 1.00 199.59 ?  43  VAL A CG1 1 
ATOM 41   C CG2 . VAL A 1 61  ? 127.430 90.317  108.065 1.00 199.59 ?  43  VAL A CG2 1 
ATOM 42   N N   . CYS A 1 62  ? 127.408 92.590  109.987 1.00 215.54 ?  44  CYS A N   1 
ATOM 43   C CA  . CYS A 1 62  ? 126.643 93.132  111.097 1.00 215.54 ?  44  CYS A CA  1 
ATOM 44   C C   . CYS A 1 62  ? 127.099 94.542  111.409 1.00 215.54 ?  44  CYS A C   1 
ATOM 45   O O   . CYS A 1 62  ? 126.280 95.419  111.703 1.00 215.54 ?  44  CYS A O   1 
ATOM 46   C CB  . CYS A 1 62  ? 126.794 92.234  112.318 1.00 215.54 ?  44  CYS A CB  1 
ATOM 47   S SG  . CYS A 1 62  ? 128.495 91.742  112.621 1.00 215.54 ?  44  CYS A SG  1 
ATOM 48   N N   . LEU A 1 63  ? 128.410 94.776  111.346 1.00 209.69 ?  45  LEU A N   1 
ATOM 49   C CA  . LEU A 1 63  ? 128.918 96.134  111.458 1.00 209.69 ?  45  LEU A CA  1 
ATOM 50   C C   . LEU A 1 63  ? 128.184 97.060  110.509 1.00 209.69 ?  45  LEU A C   1 
ATOM 51   O O   . LEU A 1 63  ? 127.760 98.152  110.900 1.00 209.69 ?  45  LEU A O   1 
ATOM 52   C CB  . LEU A 1 63  ? 130.416 96.155  111.178 1.00 209.69 ?  45  LEU A CB  1 
ATOM 53   C CG  . LEU A 1 63  ? 131.235 95.278  112.121 1.00 209.69 ?  45  LEU A CG  1 
ATOM 54   C CD1 . LEU A 1 63  ? 132.718 95.462  111.869 1.00 209.69 ?  45  LEU A CD1 1 
ATOM 55   C CD2 . LEU A 1 63  ? 130.893 95.579  113.570 1.00 209.69 ?  45  LEU A CD2 1 
ATOM 56   N N   . ILE A 1 64  ? 128.001 96.630  109.262 1.00 200.94 ?  46  ILE A N   1 
ATOM 57   C CA  . ILE A 1 64  ? 127.160 97.386  108.344 1.00 200.94 ?  46  ILE A CA  1 
ATOM 58   C C   . ILE A 1 64  ? 125.772 97.556  108.933 1.00 200.94 ?  46  ILE A C   1 
ATOM 59   O O   . ILE A 1 64  ? 125.293 98.679  109.125 1.00 200.94 ?  46  ILE A O   1 
ATOM 60   C CB  . ILE A 1 64  ? 127.108 96.697  106.977 1.00 200.94 ?  46  ILE A CB  1 
ATOM 61   C CG1 . ILE A 1 64  ? 128.524 96.485  106.473 1.00 200.94 ?  46  ILE A CG1 1 
ATOM 62   C CG2 . ILE A 1 64  ? 126.317 97.532  106.007 1.00 200.94 ?  46  ILE A CG2 1 
ATOM 63   C CD1 . ILE A 1 64  ? 128.597 95.516  105.362 1.00 200.94 ?  46  ILE A CD1 1 
ATOM 64   N N   . VAL A 1 65  ? 125.123 96.444  109.267 1.00 207.11 ?  47  VAL A N   1 
ATOM 65   C CA  . VAL A 1 65  ? 123.810 96.513  109.900 1.00 207.11 ?  47  VAL A CA  1 
ATOM 66   C C   . VAL A 1 65  ? 123.882 97.333  111.181 1.00 207.11 ?  47  VAL A C   1 
ATOM 67   O O   . VAL A 1 65  ? 122.878 97.872  111.657 1.00 207.11 ?  47  VAL A O   1 
ATOM 68   C CB  . VAL A 1 65  ? 123.275 95.097  110.161 1.00 207.11 ?  47  VAL A CB  1 
ATOM 69   C CG1 . VAL A 1 65  ? 121.819 95.147  110.536 1.00 207.11 ?  47  VAL A CG1 1 
ATOM 70   C CG2 . VAL A 1 65  ? 123.472 94.250  108.935 1.00 207.11 ?  47  VAL A CG2 1 
ATOM 71   N N   . GLY A 1 66  ? 125.084 97.502  111.715 1.00 220.63 ?  48  GLY A N   1 
ATOM 72   C CA  . GLY A 1 66  ? 125.241 98.324  112.900 1.00 220.63 ?  48  GLY A CA  1 
ATOM 73   C C   . GLY A 1 66  ? 124.930 99.779  112.608 1.00 220.63 ?  48  GLY A C   1 
ATOM 74   O O   . GLY A 1 66  ? 124.761 100.574 113.532 1.00 220.63 ?  48  GLY A O   1 
ATOM 75   N N   . ASN A 1 67  ? 124.852 100.136 111.329 1.00 240.11 ?  49  ASN A N   1 
ATOM 76   C CA  . ASN A 1 67  ? 124.594 101.525 110.954 1.00 240.11 ?  49  ASN A CA  1 
ATOM 77   C C   . ASN A 1 67  ? 123.630 101.654 109.776 1.00 240.11 ?  49  ASN A C   1 
ATOM 78   O O   . ASN A 1 67  ? 123.779 102.550 108.945 1.00 240.11 ?  49  ASN A O   1 
ATOM 79   C CB  . ASN A 1 67  ? 125.912 102.235 110.624 1.00 240.11 ?  49  ASN A CB  1 
ATOM 80   C CG  . ASN A 1 67  ? 126.631 101.614 109.441 1.00 240.11 ?  49  ASN A CG  1 
ATOM 81   O OD1 . ASN A 1 67  ? 126.552 102.114 108.319 1.00 240.11 ?  49  ASN A OD1 1 
ATOM 82   N ND2 . ASN A 1 67  ? 127.341 100.520 109.688 1.00 240.11 ?  49  ASN A ND2 1 
ATOM 83   N N   . MET A 1 68  ? 122.640 100.770 109.702 1.00 225.25 ?  50  MET A N   1 
ATOM 84   C CA  . MET A 1 68  ? 121.709 100.797 108.573 1.00 225.25 ?  50  MET A CA  1 
ATOM 85   C C   . MET A 1 68  ? 120.340 101.383 108.921 1.00 225.25 ?  50  MET A C   1 
ATOM 86   O O   . MET A 1 68  ? 119.671 101.950 108.059 1.00 225.25 ?  50  MET A O   1 
ATOM 87   C CB  . MET A 1 68  ? 121.538 99.392  107.989 1.00 225.25 ?  50  MET A CB  1 
ATOM 88   C CG  . MET A 1 68  ? 121.737 99.329  106.483 1.00 225.25 ?  50  MET A CG  1 
ATOM 89   S SD  . MET A 1 68  ? 120.192 99.471  105.563 1.00 225.25 ?  50  MET A SD  1 
ATOM 90   C CE  . MET A 1 68  ? 120.187 101.211 105.141 1.00 225.25 ?  50  MET A CE  1 
ATOM 91   N N   . ILE A 1 69  ? 119.915 101.240 110.172 1.00 207.74 ?  51  ILE A N   1 
ATOM 92   C CA  . ILE A 1 69  ? 118.602 101.743 110.578 1.00 207.74 ?  51  ILE A CA  1 
ATOM 93   C C   . ILE A 1 69  ? 118.650 102.408 111.949 1.00 207.74 ?  51  ILE A C   1 
ATOM 94   O O   . ILE A 1 69  ? 119.599 102.206 112.707 1.00 207.74 ?  51  ILE A O   1 
ATOM 95   C CB  . ILE A 1 69  ? 117.540 100.622 110.594 1.00 207.74 ?  51  ILE A CB  1 
ATOM 96   C CG1 . ILE A 1 69  ? 117.327 100.094 112.014 1.00 207.74 ?  51  ILE A CG1 1 
ATOM 97   C CG2 . ILE A 1 69  ? 117.933 99.485  109.663 1.00 207.74 ?  51  ILE A CG2 1 
ATOM 98   C CD1 . ILE A 1 69  ? 115.874 100.058 112.434 1.00 207.74 ?  51  ILE A CD1 1 
ATOM 99   N N   . GLY A 1 70  ? 117.632 103.202 112.269 1.00 209.06 ?  52  GLY A N   1 
ATOM 100  C CA  . GLY A 1 70  ? 117.590 103.858 113.564 1.00 209.06 ?  52  GLY A CA  1 
ATOM 101  C C   . GLY A 1 70  ? 116.263 103.630 114.257 1.00 209.06 ?  52  GLY A C   1 
ATOM 102  O O   . GLY A 1 70  ? 115.868 102.487 114.486 1.00 209.06 ?  52  GLY A O   1 
ATOM 103  N N   . SER A 1 71  ? 115.567 104.711 114.592 1.00 216.69 ?  53  SER A N   1 
ATOM 104  C CA  . SER A 1 71  ? 114.279 104.592 115.253 1.00 216.69 ?  53  SER A CA  1 
ATOM 105  C C   . SER A 1 71  ? 113.134 104.802 114.270 1.00 216.69 ?  53  SER A C   1 
ATOM 106  O O   . SER A 1 71  ? 111.968 104.595 114.618 1.00 216.69 ?  53  SER A O   1 
ATOM 107  C CB  . SER A 1 71  ? 114.201 105.586 116.406 1.00 216.69 ?  53  SER A CB  1 
ATOM 108  O OG  . SER A 1 71  ? 115.160 105.267 117.400 1.00 216.69 ?  53  SER A OG  1 
ATOM 109  N N   . GLY A 1 72  ? 113.457 105.189 113.034 1.00 215.60 ?  54  GLY A N   1 
ATOM 110  C CA  . GLY A 1 72  ? 112.435 105.467 112.042 1.00 215.60 ?  54  GLY A CA  1 
ATOM 111  C C   . GLY A 1 72  ? 111.454 104.338 111.828 1.00 215.60 ?  54  GLY A C   1 
ATOM 112  O O   . GLY A 1 72  ? 110.316 104.581 111.417 1.00 215.60 ?  54  GLY A O   1 
ATOM 113  N N   . ILE A 1 73  ? 111.864 103.102 112.101 1.00 207.14 ?  55  ILE A N   1 
ATOM 114  C CA  . ILE A 1 73  ? 110.962 101.975 111.942 1.00 207.14 ?  55  ILE A CA  1 
ATOM 115  C C   . ILE A 1 73  ? 109.850 101.969 112.973 1.00 207.14 ?  55  ILE A C   1 
ATOM 116  O O   . ILE A 1 73  ? 108.929 101.158 112.876 1.00 207.14 ?  55  ILE A O   1 
ATOM 117  C CB  . ILE A 1 73  ? 111.773 100.668 111.994 1.00 207.14 ?  55  ILE A CB  1 
ATOM 118  C CG1 . ILE A 1 73  ? 110.920 99.497  111.527 1.00 207.14 ?  55  ILE A CG1 1 
ATOM 119  C CG2 . ILE A 1 73  ? 112.274 100.432 113.396 1.00 207.14 ?  55  ILE A CG2 1 
ATOM 120  C CD1 . ILE A 1 73  ? 110.376 99.681  110.145 1.00 207.14 ?  55  ILE A CD1 1 
ATOM 121  N N   . PHE A 1 74  ? 109.904 102.845 113.963 1.00 200.17 ?  56  PHE A N   1 
ATOM 122  C CA  . PHE A 1 74  ? 108.827 102.950 114.929 1.00 200.17 ?  56  PHE A CA  1 
ATOM 123  C C   . PHE A 1 74  ? 107.833 104.030 114.570 1.00 200.17 ?  56  PHE A C   1 
ATOM 124  O O   . PHE A 1 74  ? 106.851 104.218 115.289 1.00 200.17 ?  56  PHE A O   1 
ATOM 125  C CB  . PHE A 1 74  ? 109.389 103.224 116.313 1.00 200.17 ?  56  PHE A CB  1 
ATOM 126  C CG  . PHE A 1 74  ? 110.305 102.162 116.802 1.00 200.17 ?  56  PHE A CG  1 
ATOM 127  C CD1 . PHE A 1 74  ? 109.828 101.123 117.566 1.00 200.17 ?  56  PHE A CD1 1 
ATOM 128  C CD2 . PHE A 1 74  ? 111.643 102.193 116.489 1.00 200.17 ?  56  PHE A CD2 1 
ATOM 129  C CE1 . PHE A 1 74  ? 110.674 100.145 118.022 1.00 200.17 ?  56  PHE A CE1 1 
ATOM 130  C CE2 . PHE A 1 74  ? 112.489 101.213 116.939 1.00 200.17 ?  56  PHE A CE2 1 
ATOM 131  C CZ  . PHE A 1 74  ? 112.005 100.188 117.707 1.00 200.17 ?  56  PHE A CZ  1 
ATOM 132  N N   . VAL A 1 75  ? 108.079 104.761 113.493 1.00 192.19 ?  57  VAL A N   1 
ATOM 133  C CA  . VAL A 1 75  ? 107.225 105.858 113.065 1.00 192.19 ?  57  VAL A CA  1 
ATOM 134  C C   . VAL A 1 75  ? 106.814 105.703 111.610 1.00 192.19 ?  57  VAL A C   1 
ATOM 135  O O   . VAL A 1 75  ? 105.628 105.753 111.278 1.00 192.19 ?  57  VAL A O   1 
ATOM 136  C CB  . VAL A 1 75  ? 107.908 107.215 113.292 1.00 192.19 ?  57  VAL A CB  1 
ATOM 137  C CG1 . VAL A 1 75  ? 107.018 108.328 112.815 1.00 192.19 ?  57  VAL A CG1 1 
ATOM 138  C CG2 . VAL A 1 75  ? 108.219 107.371 114.748 1.00 192.19 ?  57  VAL A CG2 1 
ATOM 139  N N   . SER A 1 76  ? 107.779 105.495 110.734 1.00 212.91 ?  58  SER A N   1 
ATOM 140  C CA  . SER A 1 76  ? 107.523 105.303 109.317 1.00 212.91 ?  58  SER A CA  1 
ATOM 141  C C   . SER A 1 76  ? 106.466 104.244 109.007 1.00 212.91 ?  58  SER A C   1 
ATOM 142  O O   . SER A 1 76  ? 105.832 104.339 107.950 1.00 212.91 ?  58  SER A O   1 
ATOM 143  C CB  . SER A 1 76  ? 108.829 104.959 108.610 1.00 212.91 ?  58  SER A CB  1 
ATOM 144  O OG  . SER A 1 76  ? 109.581 104.040 109.379 1.00 212.91 ?  58  SER A OG  1 
ATOM 145  N N   . PRO A 1 77  ? 106.250 103.208 109.856 1.00 196.68 ?  59  PRO A N   1 
ATOM 146  C CA  . PRO A 1 77  ? 105.143 102.285 109.590 1.00 196.68 ?  59  PRO A CA  1 
ATOM 147  C C   . PRO A 1 77  ? 103.863 102.972 109.174 1.00 196.68 ?  59  PRO A C   1 
ATOM 148  O O   . PRO A 1 77  ? 103.379 102.762 108.061 1.00 196.68 ?  59  PRO A O   1 
ATOM 149  C CB  . PRO A 1 77  ? 104.966 101.577 110.931 1.00 196.68 ?  59  PRO A CB  1 
ATOM 150  C CG  . PRO A 1 77  ? 106.322 101.482 111.447 1.00 196.68 ?  59  PRO A CG  1 
ATOM 151  C CD  . PRO A 1 77  ? 107.135 102.633 110.884 1.00 196.68 ?  59  PRO A CD  1 
ATOM 152  N N   . LYS A 1 78  ? 103.329 103.829 110.027 1.00 205.72 ?  60  LYS A N   1 
ATOM 153  C CA  . LYS A 1 78  ? 102.054 104.456 109.735 1.00 205.72 ?  60  LYS A CA  1 
ATOM 154  C C   . LYS A 1 78  ? 102.170 105.543 108.681 1.00 205.72 ?  60  LYS A C   1 
ATOM 155  O O   . LYS A 1 78  ? 101.150 106.081 108.245 1.00 205.72 ?  60  LYS A O   1 
ATOM 156  C CB  . LYS A 1 78  ? 101.441 105.016 111.017 1.00 205.72 ?  60  LYS A CB  1 
ATOM 157  C CG  . LYS A 1 78  ? 101.631 106.496 111.229 1.00 205.72 ?  60  LYS A CG  1 
ATOM 158  C CD  . LYS A 1 78  ? 100.524 107.034 112.110 1.00 205.72 ?  60  LYS A CD  1 
ATOM 159  C CE  . LYS A 1 78  ? 100.543 108.545 112.176 1.00 205.72 ?  60  LYS A CE  1 
ATOM 160  N NZ  . LYS A 1 78  ? 99.470  109.062 113.067 1.00 205.72 1  60  LYS A NZ  1 
ATOM 161  N N   . GLY A 1 79  ? 103.378 105.847 108.230 1.00 210.99 ?  61  GLY A N   1 
ATOM 162  C CA  . GLY A 1 79  ? 103.562 106.949 107.314 1.00 210.99 ?  61  GLY A CA  1 
ATOM 163  C C   . GLY A 1 79  ? 103.120 106.652 105.901 1.00 210.99 ?  61  GLY A C   1 
ATOM 164  O O   . GLY A 1 79  ? 102.442 107.471 105.277 1.00 210.99 ?  61  GLY A O   1 
ATOM 165  N N   . VAL A 1 80  ? 103.481 105.484 105.386 1.00 203.47 ?  62  VAL A N   1 
ATOM 166  C CA  . VAL A 1 80  ? 103.153 105.153 104.005 1.00 203.47 ?  62  VAL A CA  1 
ATOM 167  C C   . VAL A 1 80  ? 101.663 104.895 103.834 1.00 203.47 ?  62  VAL A C   1 
ATOM 168  O O   . VAL A 1 80  ? 101.096 105.172 102.773 1.00 203.47 ?  62  VAL A O   1 
ATOM 169  C CB  . VAL A 1 80  ? 103.994 103.950 103.548 1.00 203.47 ?  62  VAL A CB  1 
ATOM 170  C CG1 . VAL A 1 80  ? 105.444 104.334 103.471 1.00 203.47 ?  62  VAL A CG1 1 
ATOM 171  C CG2 . VAL A 1 80  ? 103.830 102.816 104.521 1.00 203.47 ?  62  VAL A CG2 1 
ATOM 172  N N   . LEU A 1 81  ? 101.008 104.378 104.872 1.00 207.26 ?  63  LEU A N   1 
ATOM 173  C CA  . LEU A 1 81  ? 99.583  104.094 104.772 1.00 207.26 ?  63  LEU A CA  1 
ATOM 174  C C   . LEU A 1 81  ? 98.794  105.350 104.451 1.00 207.26 ?  63  LEU A C   1 
ATOM 175  O O   . LEU A 1 81  ? 97.936  105.340 103.563 1.00 207.26 ?  63  LEU A O   1 
ATOM 176  C CB  . LEU A 1 81  ? 99.091  103.464 106.067 1.00 207.26 ?  63  LEU A CB  1 
ATOM 177  C CG  . LEU A 1 81  ? 99.724  102.099 106.286 1.00 207.26 ?  63  LEU A CG  1 
ATOM 178  C CD1 . LEU A 1 81  ? 99.024  101.353 107.397 1.00 207.26 ?  63  LEU A CD1 1 
ATOM 179  C CD2 . LEU A 1 81  ? 99.670  101.321 104.994 1.00 207.26 ?  63  LEU A CD2 1 
ATOM 180  N N   . ILE A 1 82  ? 99.093  106.450 105.140 1.00 213.98 ?  64  ILE A N   1 
ATOM 181  C CA  . ILE A 1 82  ? 98.422  107.713 104.888 1.00 213.98 ?  64  ILE A CA  1 
ATOM 182  C C   . ILE A 1 82  ? 98.490  108.122 103.428 1.00 213.98 ?  64  ILE A C   1 
ATOM 183  O O   . ILE A 1 82  ? 97.690  108.945 102.981 1.00 213.98 ?  64  ILE A O   1 
ATOM 184  C CB  . ILE A 1 82  ? 99.031  108.813 105.780 1.00 213.98 ?  64  ILE A CB  1 
ATOM 185  C CG1 . ILE A 1 82  ? 99.146  108.322 107.217 1.00 213.98 ?  64  ILE A CG1 1 
ATOM 186  C CG2 . ILE A 1 82  ? 98.180  110.063 105.753 1.00 213.98 ?  64  ILE A CG2 1 
ATOM 187  C CD1 . ILE A 1 82  ? 97.823  108.132 107.884 1.00 213.98 ?  64  ILE A CD1 1 
ATOM 188  N N   . TYR A 1 83  ? 99.410  107.551 102.664 1.00 209.36 ?  65  TYR A N   1 
ATOM 189  C CA  . TYR A 1 83  ? 99.542  107.889 101.261 1.00 209.36 ?  65  TYR A CA  1 
ATOM 190  C C   . TYR A 1 83  ? 99.279  106.713 100.344 1.00 209.36 ?  65  TYR A C   1 
ATOM 191  O O   . TYR A 1 83  ? 99.331  106.876 99.121  1.00 209.36 ?  65  TYR A O   1 
ATOM 192  C CB  . TYR A 1 83  ? 100.934 108.457 100.999 1.00 209.36 ?  65  TYR A CB  1 
ATOM 193  C CG  . TYR A 1 83  ? 101.210 109.648 101.865 1.00 209.36 ?  65  TYR A CG  1 
ATOM 194  C CD1 . TYR A 1 83  ? 100.245 110.617 102.053 1.00 209.36 ?  65  TYR A CD1 1 
ATOM 195  C CD2 . TYR A 1 83  ? 102.419 109.792 102.515 1.00 209.36 ?  65  TYR A CD2 1 
ATOM 196  C CE1 . TYR A 1 83  ? 100.483 111.702 102.846 1.00 209.36 ?  65  TYR A CE1 1 
ATOM 197  C CE2 . TYR A 1 83  ? 102.666 110.877 103.312 1.00 209.36 ?  65  TYR A CE2 1 
ATOM 198  C CZ  . TYR A 1 83  ? 101.695 111.829 103.473 1.00 209.36 ?  65  TYR A CZ  1 
ATOM 199  O OH  . TYR A 1 83  ? 101.933 112.918 104.271 1.00 209.36 ?  65  TYR A OH  1 
ATOM 200  N N   . SER A 1 84  ? 99.011  105.560 100.879 1.00 213.24 ?  66  SER A N   1 
ATOM 201  C CA  . SER A 1 84  ? 98.673  104.444 100.015 1.00 213.24 ?  66  SER A CA  1 
ATOM 202  C C   . SER A 1 84  ? 97.293  103.880 100.283 1.00 213.24 ?  66  SER A C   1 
ATOM 203  O O   . SER A 1 84  ? 96.513  103.715 99.345  1.00 213.24 ?  66  SER A O   1 
ATOM 204  C CB  . SER A 1 84  ? 99.703  103.334 100.186 1.00 213.24 ?  66  SER A CB  1 
ATOM 205  O OG  . SER A 1 84  ? 99.149  102.082 99.819  1.00 213.24 ?  66  SER A OG  1 
ATOM 206  N N   . ALA A 1 85  ? 96.992  103.547 101.535 1.00 215.56 ?  67  ALA A N   1 
ATOM 207  C CA  . ALA A 1 85  ? 95.786  102.865 101.982 1.00 215.56 ?  67  ALA A CA  1 
ATOM 208  C C   . ALA A 1 85  ? 95.710  101.449 101.443 1.00 215.56 ?  67  ALA A C   1 
ATOM 209  O O   . ALA A 1 85  ? 94.846  100.682 101.869 1.00 215.56 ?  67  ALA A O   1 
ATOM 210  C CB  . ALA A 1 85  ? 94.503  103.617 101.606 1.00 215.56 ?  67  ALA A CB  1 
ATOM 211  N N   . SER A 1 86  ? 96.608  101.066 100.552 1.00 226.00 ?  68  SER A N   1 
ATOM 212  C CA  . SER A 1 86  ? 96.666  99.722  100.010 1.00 226.00 ?  68  SER A CA  1 
ATOM 213  C C   . SER A 1 86  ? 97.829  99.017  100.672 1.00 226.00 ?  68  SER A C   1 
ATOM 214  O O   . SER A 1 86  ? 98.989  99.337  100.392 1.00 226.00 ?  68  SER A O   1 
ATOM 215  C CB  . SER A 1 86  ? 96.847  99.740  98.495  1.00 226.00 ?  68  SER A CB  1 
ATOM 216  O OG  . SER A 1 86  ? 97.449  98.536  98.055  1.00 226.00 ?  68  SER A OG  1 
ATOM 217  N N   . PHE A 1 87  ? 97.519  98.074  101.557 1.00 229.40 ?  69  PHE A N   1 
ATOM 218  C CA  . PHE A 1 87  ? 98.577  97.333  102.224 1.00 229.40 ?  69  PHE A CA  1 
ATOM 219  C C   . PHE A 1 87  ? 99.555  96.771  101.208 1.00 229.40 ?  69  PHE A C   1 
ATOM 220  O O   . PHE A 1 87  ? 100.775 96.837  101.401 1.00 229.40 ?  69  PHE A O   1 
ATOM 221  C CB  . PHE A 1 87  ? 97.987  96.208  103.063 1.00 229.40 ?  69  PHE A CB  1 
ATOM 222  C CG  . PHE A 1 87  ? 97.194  96.679  104.233 1.00 229.40 ?  69  PHE A CG  1 
ATOM 223  C CD1 . PHE A 1 87  ? 96.867  98.011  104.381 1.00 229.40 ?  69  PHE A CD1 1 
ATOM 224  C CD2 . PHE A 1 87  ? 96.777  95.784  105.194 1.00 229.40 ?  69  PHE A CD2 1 
ATOM 225  C CE1 . PHE A 1 87  ? 96.136  98.438  105.457 1.00 229.40 ?  69  PHE A CE1 1 
ATOM 226  C CE2 . PHE A 1 87  ? 96.044  96.205  106.276 1.00 229.40 ?  69  PHE A CE2 1 
ATOM 227  C CZ  . PHE A 1 87  ? 95.724  97.535  106.409 1.00 229.40 ?  69  PHE A CZ  1 
ATOM 228  N N   . GLY A 1 88  ? 99.032  96.234  100.107 1.00 245.76 ?  70  GLY A N   1 
ATOM 229  C CA  . GLY A 1 88  ? 99.901  95.757  99.048  1.00 245.76 ?  70  GLY A CA  1 
ATOM 230  C C   . GLY A 1 88  ? 100.799 96.853  98.515  1.00 245.76 ?  70  GLY A C   1 
ATOM 231  O O   . GLY A 1 88  ? 102.009 96.665  98.360  1.00 245.76 ?  70  GLY A O   1 
ATOM 232  N N   . LEU A 1 89  ? 100.221 98.022  98.241  1.00 224.52 ?  71  LEU A N   1 
ATOM 233  C CA  . LEU A 1 89  ? 101.043 99.124  97.771  1.00 224.52 ?  71  LEU A CA  1 
ATOM 234  C C   . LEU A 1 89  ? 102.066 99.513  98.826  1.00 224.52 ?  71  LEU A C   1 
ATOM 235  O O   . LEU A 1 89  ? 103.201 99.864  98.498  1.00 224.52 ?  71  LEU A O   1 
ATOM 236  C CB  . LEU A 1 89  ? 100.171 100.317 97.389  1.00 224.52 ?  71  LEU A CB  1 
ATOM 237  C CG  . LEU A 1 89  ? 100.873 101.398 96.565  1.00 224.52 ?  71  LEU A CG  1 
ATOM 238  C CD1 . LEU A 1 89  ? 99.878  102.076 95.677  1.00 224.52 ?  71  LEU A CD1 1 
ATOM 239  C CD2 . LEU A 1 89  ? 101.559 102.434 97.420  1.00 224.52 ?  71  LEU A CD2 1 
ATOM 240  N N   . SER A 1 90  ? 101.691 99.433  100.102 1.00 227.63 ?  72  SER A N   1 
ATOM 241  C CA  . SER A 1 90  ? 102.640 99.753  101.159 1.00 227.63 ?  72  SER A CA  1 
ATOM 242  C C   . SER A 1 90  ? 103.842 98.819  101.122 1.00 227.63 ?  72  SER A C   1 
ATOM 243  O O   . SER A 1 90  ? 104.997 99.269  101.140 1.00 227.63 ?  72  SER A O   1 
ATOM 244  C CB  . SER A 1 90  ? 101.946 99.679  102.513 1.00 227.63 ?  72  SER A CB  1 
ATOM 245  O OG  . SER A 1 90  ? 101.675 98.334  102.848 1.00 227.63 ?  72  SER A OG  1 
ATOM 246  N N   . LEU A 1 91  ? 103.593 97.512  101.078 1.00 233.66 ?  73  LEU A N   1 
ATOM 247  C CA  . LEU A 1 91  ? 104.700 96.567  101.025 1.00 233.66 ?  73  LEU A CA  1 
ATOM 248  C C   . LEU A 1 91  ? 105.535 96.781  99.774  1.00 233.66 ?  73  LEU A C   1 
ATOM 249  O O   . LEU A 1 91  ? 106.767 96.644  99.800  1.00 233.66 ?  73  LEU A O   1 
ATOM 250  C CB  . LEU A 1 91  ? 104.174 95.138  101.080 1.00 233.66 ?  73  LEU A CB  1 
ATOM 251  C CG  . LEU A 1 91  ? 103.929 94.573  102.477 1.00 233.66 ?  73  LEU A CG  1 
ATOM 252  C CD1 . LEU A 1 91  ? 105.223 94.545  103.253 1.00 233.66 ?  73  LEU A CD1 1 
ATOM 253  C CD2 . LEU A 1 91  ? 102.887 95.358  103.228 1.00 233.66 ?  73  LEU A CD2 1 
ATOM 254  N N   . VAL A 1 92  ? 104.879 97.121  98.667  1.00 232.57 ?  74  VAL A N   1 
ATOM 255  C CA  . VAL A 1 92  ? 105.610 97.433  97.450  1.00 232.57 ?  74  VAL A CA  1 
ATOM 256  C C   . VAL A 1 92  ? 106.547 98.608  97.682  1.00 232.57 ?  74  VAL A C   1 
ATOM 257  O O   . VAL A 1 92  ? 107.705 98.592  97.250  1.00 232.57 ?  74  VAL A O   1 
ATOM 258  C CB  . VAL A 1 92  ? 104.628 97.705  96.302  1.00 232.57 ?  74  VAL A CB  1 
ATOM 259  C CG1 . VAL A 1 92  ? 105.320 98.438  95.175  1.00 232.57 ?  74  VAL A CG1 1 
ATOM 260  C CG2 . VAL A 1 92  ? 104.050 96.402  95.812  1.00 232.57 ?  74  VAL A CG2 1 
ATOM 261  N N   . ILE A 1 93  ? 106.066 99.642  98.372  1.00 222.26 ?  75  ILE A N   1 
ATOM 262  C CA  . ILE A 1 93  ? 106.911 100.799 98.651  1.00 222.26 ?  75  ILE A CA  1 
ATOM 263  C C   . ILE A 1 93  ? 108.109 100.387 99.487  1.00 222.26 ?  75  ILE A C   1 
ATOM 264  O O   . ILE A 1 93  ? 109.236 100.843 99.256  1.00 222.26 ?  75  ILE A O   1 
ATOM 265  C CB  . ILE A 1 93  ? 106.105 101.909 99.343  1.00 222.26 ?  75  ILE A CB  1 
ATOM 266  C CG1 . ILE A 1 93  ? 104.921 102.303 98.483  1.00 222.26 ?  75  ILE A CG1 1 
ATOM 267  C CG2 . ILE A 1 93  ? 106.969 103.115 99.570  1.00 222.26 ?  75  ILE A CG2 1 
ATOM 268  C CD1 . ILE A 1 93  ? 105.291 102.618 97.077  1.00 222.26 ?  75  ILE A CD1 1 
ATOM 269  N N   . TRP A 1 94  ? 107.889 99.519  100.471 1.00 232.70 ?  76  TRP A N   1 
ATOM 270  C CA  . TRP A 1 94  ? 109.007 99.082  101.300 1.00 232.70 ?  76  TRP A CA  1 
ATOM 271  C C   . TRP A 1 94  ? 110.071 98.377  100.467 1.00 232.70 ?  76  TRP A C   1 
ATOM 272  O O   . TRP A 1 94  ? 111.262 98.700  100.559 1.00 232.70 ?  76  TRP A O   1 
ATOM 273  C CB  . TRP A 1 94  ? 108.518 98.174  102.421 1.00 232.70 ?  76  TRP A CB  1 
ATOM 274  C CG  . TRP A 1 94  ? 108.048 98.912  103.634 1.00 232.70 ?  76  TRP A CG  1 
ATOM 275  C CD1 . TRP A 1 94  ? 106.870 98.735  104.284 1.00 232.70 ?  76  TRP A CD1 1 
ATOM 276  C CD2 . TRP A 1 94  ? 108.745 99.941  104.346 1.00 232.70 ?  76  TRP A CD2 1 
ATOM 277  N NE1 . TRP A 1 94  ? 106.782 99.587  105.353 1.00 232.70 ?  76  TRP A NE1 1 
ATOM 278  C CE2 . TRP A 1 94  ? 107.924 100.336 105.414 1.00 232.70 ?  76  TRP A CE2 1 
ATOM 279  C CE3 . TRP A 1 94  ? 109.982 100.565 104.185 1.00 232.70 ?  76  TRP A CE3 1 
ATOM 280  C CZ2 . TRP A 1 94  ? 108.296 101.324 106.312 1.00 232.70 ?  76  TRP A CZ2 1 
ATOM 281  C CZ3 . TRP A 1 94  ? 110.348 101.547 105.079 1.00 232.70 ?  76  TRP A CZ3 1 
ATOM 282  C CH2 . TRP A 1 94  ? 109.510 101.917 106.127 1.00 232.70 ?  76  TRP A CH2 1 
ATOM 283  N N   . ALA A 1 95  ? 109.663 97.416  99.640  1.00 253.07 ?  77  ALA A N   1 
ATOM 284  C CA  . ALA A 1 95  ? 110.649 96.695  98.839  1.00 253.07 ?  77  ALA A CA  1 
ATOM 285  C C   . ALA A 1 95  ? 111.360 97.628  97.866  1.00 253.07 ?  77  ALA A C   1 
ATOM 286  O O   . ALA A 1 95  ? 112.575 97.498  97.625  1.00 253.07 ?  77  ALA A O   1 
ATOM 287  C CB  . ALA A 1 95  ? 109.982 95.548  98.088  1.00 253.07 ?  77  ALA A CB  1 
ATOM 288  N N   . VAL A 1 96  ? 110.613 98.565  97.282  1.00 255.75 ?  78  VAL A N   1 
ATOM 289  C CA  . VAL A 1 96  ? 111.218 99.534  96.380  1.00 255.75 ?  78  VAL A CA  1 
ATOM 290  C C   . VAL A 1 96  ? 112.301 100.312 97.104  1.00 255.75 ?  78  VAL A C   1 
ATOM 291  O O   . VAL A 1 96  ? 113.413 100.485 96.589  1.00 255.75 ?  78  VAL A O   1 
ATOM 292  C CB  . VAL A 1 96  ? 110.141 100.464 95.796  1.00 255.75 ?  78  VAL A CB  1 
ATOM 293  C CG1 . VAL A 1 96  ? 110.770 101.727 95.241  1.00 255.75 ?  78  VAL A CG1 1 
ATOM 294  C CG2 . VAL A 1 96  ? 109.364 99.747  94.714  1.00 255.75 ?  78  VAL A CG2 1 
ATOM 295  N N   . GLY A 1 97  ? 111.996 100.785 98.310  1.00 264.68 ?  79  GLY A N   1 
ATOM 296  C CA  . GLY A 1 97  ? 113.011 101.460 99.095  1.00 264.68 ?  79  GLY A CA  1 
ATOM 297  C C   . GLY A 1 97  ? 114.224 100.586 99.333  1.00 264.68 ?  79  GLY A C   1 
ATOM 298  O O   . GLY A 1 97  ? 115.361 101.063 99.302  1.00 264.68 ?  79  GLY A O   1 
ATOM 299  N N   . GLY A 1 98  ? 113.997 99.297  99.578  1.00 271.64 ?  80  GLY A N   1 
ATOM 300  C CA  . GLY A 1 98  ? 115.118 98.392  99.768  1.00 271.64 ?  80  GLY A CA  1 
ATOM 301  C C   . GLY A 1 98  ? 116.083 98.422  98.599  1.00 271.64 ?  80  GLY A C   1 
ATOM 302  O O   . GLY A 1 98  ? 117.279 98.697  98.761  1.00 271.64 ?  80  GLY A O   1 
ATOM 303  N N   . LEU A 1 99  ? 115.572 98.165  97.398  1.00 271.98 ?  81  LEU A N   1 
ATOM 304  C CA  . LEU A 1 99  ? 116.470 98.140  96.244  1.00 271.98 ?  81  LEU A CA  1 
ATOM 305  C C   . LEU A 1 99  ? 117.085 99.515  96.001  1.00 271.98 ?  81  LEU A C   1 
ATOM 306  O O   . LEU A 1 99  ? 118.253 99.632  95.594  1.00 271.98 ?  81  LEU A O   1 
ATOM 307  C CB  . LEU A 1 99  ? 115.733 97.649  95.000  1.00 271.98 ?  81  LEU A CB  1 
ATOM 308  C CG  . LEU A 1 99  ? 114.767 98.566  94.250  1.00 271.98 ?  81  LEU A CG  1 
ATOM 309  C CD1 . LEU A 1 99  ? 115.481 99.415  93.205  1.00 271.98 ?  81  LEU A CD1 1 
ATOM 310  C CD2 . LEU A 1 99  ? 113.679 97.744  93.597  1.00 271.98 ?  81  LEU A CD2 1 
ATOM 311  N N   . PHE A 1 100 ? 116.304 100.566 96.233  1.00 274.92 ?  82  PHE A N   1 
ATOM 312  C CA  . PHE A 1 100 ? 116.783 101.924 96.027  1.00 274.92 ?  82  PHE A CA  1 
ATOM 313  C C   . PHE A 1 100 ? 118.017 102.178 96.877  1.00 274.92 ?  82  PHE A C   1 
ATOM 314  O O   . PHE A 1 100 ? 119.058 102.646 96.392  1.00 274.92 ?  82  PHE A O   1 
ATOM 315  C CB  . PHE A 1 100 ? 115.670 102.884 96.418  1.00 274.92 ?  82  PHE A CB  1 
ATOM 316  C CG  . PHE A 1 100 ? 115.684 104.169 95.681  1.00 274.92 ?  82  PHE A CG  1 
ATOM 317  C CD1 . PHE A 1 100 ? 114.797 104.381 94.652  1.00 274.92 ?  82  PHE A CD1 1 
ATOM 318  C CD2 . PHE A 1 100 ? 116.592 105.155 95.993  1.00 274.92 ?  82  PHE A CD2 1 
ATOM 319  C CE1 . PHE A 1 100 ? 114.780 105.568 93.976  1.00 274.92 ?  82  PHE A CE1 1 
ATOM 320  C CE2 . PHE A 1 100 ? 116.595 106.350 95.302  1.00 274.92 ?  82  PHE A CE2 1 
ATOM 321  C CZ  . PHE A 1 100 ? 115.684 106.554 94.294  1.00 274.92 ?  82  PHE A CZ  1 
ATOM 322  N N   . SER A 1 101 ? 117.906 101.858 98.160  1.00 275.56 ?  83  SER A N   1 
ATOM 323  C CA  . SER A 1 101 ? 119.027 102.003 99.067  1.00 275.56 ?  83  SER A CA  1 
ATOM 324  C C   . SER A 1 101 ? 120.193 101.137 98.632  1.00 275.56 ?  83  SER A C   1 
ATOM 325  O O   . SER A 1 101 ? 121.351 101.514 98.818  1.00 275.56 ?  83  SER A O   1 
ATOM 326  C CB  . SER A 1 101 ? 118.588 101.636 100.477 1.00 275.56 ?  83  SER A CB  1 
ATOM 327  O OG  . SER A 1 101 ? 117.844 100.432 100.448 1.00 275.56 ?  83  SER A OG  1 
ATOM 328  N N   . VAL A 1 102 ? 119.914 99.950  98.094  1.00 259.08 ?  84  VAL A N   1 
ATOM 329  C CA  . VAL A 1 102 ? 121.010 99.128  97.589  1.00 259.08 ?  84  VAL A CA  1 
ATOM 330  C C   . VAL A 1 102 ? 121.835 99.926  96.598  1.00 259.08 ?  84  VAL A C   1 
ATOM 331  O O   . VAL A 1 102 ? 123.052 100.093 96.759  1.00 259.08 ?  84  VAL A O   1 
ATOM 332  C CB  . VAL A 1 102 ? 120.477 97.836  96.953  1.00 259.08 ?  84  VAL A CB  1 
ATOM 333  C CG1 . VAL A 1 102 ? 121.515 97.262  96.020  1.00 259.08 ?  84  VAL A CG1 1 
ATOM 334  C CG2 . VAL A 1 102 ? 120.126 96.834  98.024  1.00 259.08 ?  84  VAL A CG2 1 
ATOM 335  N N   . PHE A 1 103 ? 121.170 100.443 95.569  1.00 271.27 ?  85  PHE A N   1 
ATOM 336  C CA  . PHE A 1 103 ? 121.843 101.282 94.583  1.00 271.27 ?  85  PHE A CA  1 
ATOM 337  C C   . PHE A 1 103 ? 122.662 102.380 95.250  1.00 271.27 ?  85  PHE A C   1 
ATOM 338  O O   . PHE A 1 103 ? 123.866 102.544 94.984  1.00 271.27 ?  85  PHE A O   1 
ATOM 339  C CB  . PHE A 1 103 ? 120.806 101.899 93.653  1.00 271.27 ?  85  PHE A CB  1 
ATOM 340  C CG  . PHE A 1 103 ? 120.539 101.100 92.426  1.00 271.27 ?  85  PHE A CG  1 
ATOM 341  C CD1 . PHE A 1 103 ? 121.189 101.391 91.247  1.00 271.27 ?  85  PHE A CD1 1 
ATOM 342  C CD2 . PHE A 1 103 ? 119.650 100.049 92.455  1.00 271.27 ?  85  PHE A CD2 1 
ATOM 343  C CE1 . PHE A 1 103 ? 120.940 100.661 90.119  1.00 271.27 ?  85  PHE A CE1 1 
ATOM 344  C CE2 . PHE A 1 103 ? 119.406 99.312  91.329  1.00 271.27 ?  85  PHE A CE2 1 
ATOM 345  C CZ  . PHE A 1 103 ? 120.053 99.616  90.160  1.00 271.27 ?  85  PHE A CZ  1 
ATOM 346  N N   . GLY A 1 104 ? 122.013 103.148 96.120  1.00 271.16 ?  86  GLY A N   1 
ATOM 347  C CA  . GLY A 1 104 ? 122.679 104.303 96.695  1.00 271.16 ?  86  GLY A CA  1 
ATOM 348  C C   . GLY A 1 104 ? 123.904 103.933 97.502  1.00 271.16 ?  86  GLY A C   1 
ATOM 349  O O   . GLY A 1 104 ? 124.947 104.588 97.408  1.00 271.16 ?  86  GLY A O   1 
ATOM 350  N N   . ALA A 1 105 ? 123.784 102.902 98.327  1.00 254.63 ?  87  ALA A N   1 
ATOM 351  C CA  . ALA A 1 105 ? 124.912 102.482 99.131  1.00 254.63 ?  87  ALA A CA  1 
ATOM 352  C C   . ALA A 1 105 ? 126.058 102.023 98.256  1.00 254.63 ?  87  ALA A C   1 
ATOM 353  O O   . ALA A 1 105 ? 127.217 102.294 98.577  1.00 254.63 ?  87  ALA A O   1 
ATOM 354  C CB  . ALA A 1 105 ? 124.479 101.383 100.092 1.00 254.63 ?  87  ALA A CB  1 
ATOM 355  N N   . LEU A 1 106 ? 125.762 101.353 97.138  1.00 258.91 ?  88  LEU A N   1 
ATOM 356  C CA  . LEU A 1 106 ? 126.832 101.042 96.194  1.00 258.91 ?  88  LEU A CA  1 
ATOM 357  C C   . LEU A 1 106 ? 127.554 102.307 95.764  1.00 258.91 ?  88  LEU A C   1 
ATOM 358  O O   . LEU A 1 106 ? 128.790 102.385 95.808  1.00 258.91 ?  88  LEU A O   1 
ATOM 359  C CB  . LEU A 1 106 ? 126.295 100.316 94.962  1.00 258.91 ?  88  LEU A CB  1 
ATOM 360  C CG  . LEU A 1 106 ? 125.328 99.148  95.087  1.00 258.91 ?  88  LEU A CG  1 
ATOM 361  C CD1 . LEU A 1 106 ? 124.820 98.750  93.715  1.00 258.91 ?  88  LEU A CD1 1 
ATOM 362  C CD2 . LEU A 1 106 ? 126.008 97.980  95.768  1.00 258.91 ?  88  LEU A CD2 1 
ATOM 363  N N   . CYS A 1 107 ? 126.794 103.306 95.330  1.00 256.57 ?  89  CYS A N   1 
ATOM 364  C CA  . CYS A 1 107 ? 127.431 104.502 94.791  1.00 256.57 ?  89  CYS A CA  1 
ATOM 365  C C   . CYS A 1 107 ? 128.299 105.187 95.844  1.00 256.57 ?  89  CYS A C   1 
ATOM 366  O O   . CYS A 1 107 ? 129.464 105.530 95.586  1.00 256.57 ?  89  CYS A O   1 
ATOM 367  C CB  . CYS A 1 107 ? 126.367 105.443 94.241  1.00 256.57 ?  89  CYS A CB  1 
ATOM 368  S SG  . CYS A 1 107 ? 125.287 104.632 93.042  1.00 256.57 ?  89  CYS A SG  1 
ATOM 369  N N   . TYR A 1 108 ? 127.759 105.375 97.049  1.00 229.60 ?  90  TYR A N   1 
ATOM 370  C CA  . TYR A 1 108 ? 128.555 106.015 98.092  1.00 229.60 ?  90  TYR A CA  1 
ATOM 371  C C   . TYR A 1 108 ? 129.754 105.179 98.491  1.00 229.60 ?  90  TYR A C   1 
ATOM 372  O O   . TYR A 1 108 ? 130.804 105.737 98.818  1.00 229.60 ?  90  TYR A O   1 
ATOM 373  C CB  . TYR A 1 108 ? 127.720 106.327 99.329  1.00 229.60 ?  90  TYR A CB  1 
ATOM 374  C CG  . TYR A 1 108 ? 127.046 107.671 99.280  1.00 229.60 ?  90  TYR A CG  1 
ATOM 375  C CD1 . TYR A 1 108 ? 127.434 108.620 98.357  1.00 229.60 ?  90  TYR A CD1 1 
ATOM 376  C CD2 . TYR A 1 108 ? 126.050 108.002 100.176 1.00 229.60 ?  90  TYR A CD2 1 
ATOM 377  C CE1 . TYR A 1 108 ? 126.834 109.845 98.314  1.00 229.60 ?  90  TYR A CE1 1 
ATOM 378  C CE2 . TYR A 1 108 ? 125.445 109.226 100.138 1.00 229.60 ?  90  TYR A CE2 1 
ATOM 379  C CZ  . TYR A 1 108 ? 125.843 110.143 99.205  1.00 229.60 ?  90  TYR A CZ  1 
ATOM 380  O OH  . TYR A 1 108 ? 125.246 111.374 99.159  1.00 229.60 ?  90  TYR A OH  1 
ATOM 381  N N   . ALA A 1 109 ? 129.624 103.857 98.505  1.00 217.67 ?  91  ALA A N   1 
ATOM 382  C CA  . ALA A 1 109 ? 130.773 103.041 98.858  1.00 217.67 ?  91  ALA A CA  1 
ATOM 383  C C   . ALA A 1 109 ? 131.880 103.219 97.838  1.00 217.67 ?  91  ALA A C   1 
ATOM 384  O O   . ALA A 1 109 ? 133.058 103.318 98.196  1.00 217.67 ?  91  ALA A O   1 
ATOM 385  C CB  . ALA A 1 109 ? 130.363 101.577 98.966  1.00 217.67 ?  91  ALA A CB  1 
ATOM 386  N N   . GLU A 1 110 ? 131.515 103.281 96.562  1.00 226.98 ?  92  GLU A N   1 
ATOM 387  C CA  . GLU A 1 110 ? 132.502 103.578 95.532  1.00 226.98 ?  92  GLU A CA  1 
ATOM 388  C C   . GLU A 1 110 ? 133.184 104.914 95.798  1.00 226.98 ?  92  GLU A C   1 
ATOM 389  O O   . GLU A 1 110 ? 134.421 105.013 95.812  1.00 226.98 ?  92  GLU A O   1 
ATOM 390  C CB  . GLU A 1 110 ? 131.820 103.568 94.168  1.00 226.98 ?  92  GLU A CB  1 
ATOM 391  C CG  . GLU A 1 110 ? 132.710 103.878 92.980  1.00 226.98 ?  92  GLU A CG  1 
ATOM 392  C CD  . GLU A 1 110 ? 132.744 105.364 92.654  1.00 226.98 ?  92  GLU A CD  1 
ATOM 393  O OE1 . GLU A 1 110 ? 131.786 106.080 93.016  1.00 226.98 ?  92  GLU A OE1 1 
ATOM 394  O OE2 . GLU A 1 110 ? 133.709 105.814 92.004  1.00 226.98 -1 92  GLU A OE2 1 
ATOM 395  N N   . LEU A 1 111 ? 132.388 105.954 96.026  1.00 222.33 ?  93  LEU A N   1 
ATOM 396  C CA  . LEU A 1 111 ? 132.968 107.281 96.188  1.00 222.33 ?  93  LEU A CA  1 
ATOM 397  C C   . LEU A 1 111 ? 133.906 107.340 97.385  1.00 222.33 ?  93  LEU A C   1 
ATOM 398  O O   . LEU A 1 111 ? 135.079 107.720 97.256  1.00 222.33 ?  93  LEU A O   1 
ATOM 399  C CB  . LEU A 1 111 ? 131.868 108.321 96.322  1.00 222.33 ?  93  LEU A CB  1 
ATOM 400  C CG  . LEU A 1 111 ? 131.404 108.767 94.948  1.00 222.33 ?  93  LEU A CG  1 
ATOM 401  C CD1 . LEU A 1 111 ? 130.464 109.944 95.079  1.00 222.33 ?  93  LEU A CD1 1 
ATOM 402  C CD2 . LEU A 1 111 ? 132.623 109.114 94.116  1.00 222.33 ?  93  LEU A CD2 1 
ATOM 403  N N   . GLY A 1 112 ? 133.407 106.943 98.554  1.00 210.13 ?  94  GLY A N   1 
ATOM 404  C CA  . GLY A 1 112 ? 134.153 107.066 99.789  1.00 210.13 ?  94  GLY A CA  1 
ATOM 405  C C   . GLY A 1 112 ? 135.526 106.444 99.752  1.00 210.13 ?  94  GLY A C   1 
ATOM 406  O O   . GLY A 1 112 ? 136.377 106.798 100.569 1.00 210.13 ?  94  GLY A O   1 
ATOM 407  N N   . THR A 1 113 ? 135.755 105.555 98.791  1.00 202.66 ?  95  THR A N   1 
ATOM 408  C CA  . THR A 1 113 ? 137.073 104.956 98.633  1.00 202.66 ?  95  THR A CA  1 
ATOM 409  C C   . THR A 1 113 ? 137.765 105.530 97.399  1.00 202.66 ?  95  THR A C   1 
ATOM 410  O O   . THR A 1 113 ? 138.973 105.762 97.416  1.00 202.66 ?  95  THR A O   1 
ATOM 411  C CB  . THR A 1 113 ? 136.998 103.420 98.532  1.00 202.66 ?  95  THR A CB  1 
ATOM 412  O OG1 . THR A 1 113 ? 138.322 102.881 98.427  1.00 202.66 ?  95  THR A OG1 1 
ATOM 413  C CG2 . THR A 1 113 ? 136.186 102.993 97.318  1.00 202.66 ?  95  THR A CG2 1 
ATOM 414  N N   . THR A 1 114 ? 137.006 105.766 96.332  1.00 208.31 ?  96  THR A N   1 
ATOM 415  C CA  . THR A 1 114 ? 137.584 106.347 95.123  1.00 208.31 ?  96  THR A CA  1 
ATOM 416  C C   . THR A 1 114 ? 137.811 107.833 95.321  1.00 208.31 ?  96  THR A C   1 
ATOM 417  O O   . THR A 1 114 ? 138.952 108.292 95.325  1.00 208.31 ?  96  THR A O   1 
ATOM 418  C CB  . THR A 1 114 ? 136.691 106.125 93.889  1.00 208.31 ?  96  THR A CB  1 
ATOM 419  O OG1 . THR A 1 114 ? 135.388 106.669 94.133  1.00 208.31 ?  96  THR A OG1 1 
ATOM 420  C CG2 . THR A 1 114 ? 136.571 104.641 93.579  1.00 208.31 ?  96  THR A CG2 1 
ATOM 421  N N   . ILE A 1 115 ? 136.733 108.590 95.497  1.00 206.02 ?  97  ILE A N   1 
ATOM 422  C CA  . ILE A 1 115 ? 136.881 110.013 95.774  1.00 206.02 ?  97  ILE A CA  1 
ATOM 423  C C   . ILE A 1 115 ? 137.560 110.143 97.125  1.00 206.02 ?  97  ILE A C   1 
ATOM 424  O O   . ILE A 1 115 ? 138.367 111.047 97.331  1.00 206.02 ?  97  ILE A O   1 
ATOM 425  C CB  . ILE A 1 115 ? 135.529 110.757 95.748  1.00 206.02 ?  97  ILE A CB  1 
ATOM 426  C CG1 . ILE A 1 115 ? 135.718 112.183 95.225  1.00 206.02 ?  97  ILE A CG1 1 
ATOM 427  C CG2 . ILE A 1 115 ? 134.884 110.779 97.125  1.00 206.02 ?  97  ILE A CG2 1 
ATOM 428  C CD1 . ILE A 1 115 ? 134.519 113.079 95.446  1.00 206.02 ?  97  ILE A CD1 1 
ATOM 429  N N   . LYS A 1 116 ? 137.240 109.241 98.047  1.00 217.04 ?  98  LYS A N   1 
ATOM 430  C CA  . LYS A 1 116 ? 137.890 109.245 99.355  1.00 217.04 ?  98  LYS A CA  1 
ATOM 431  C C   . LYS A 1 116 ? 137.961 110.633 99.977  1.00 217.04 ?  98  LYS A C   1 
ATOM 432  O O   . LYS A 1 116 ? 139.030 111.073 100.396 1.00 217.04 ?  98  LYS A O   1 
ATOM 433  C CB  . LYS A 1 116 ? 139.297 108.652 99.244  1.00 217.04 ?  98  LYS A CB  1 
ATOM 434  C CG  . LYS A 1 116 ? 139.507 107.402 100.082 1.00 217.04 ?  98  LYS A CG  1 
ATOM 435  C CD  . LYS A 1 116 ? 140.067 107.745 101.452 1.00 217.04 ?  98  LYS A CD  1 
ATOM 436  C CE  . LYS A 1 116 ? 138.956 107.980 102.462 1.00 217.04 ?  98  LYS A CE  1 
ATOM 437  N NZ  . LYS A 1 116 ? 138.814 109.425 102.790 1.00 217.04 1  98  LYS A NZ  1 
ATOM 438  N N   . LYS A 1 117 ? 136.829 111.324 100.040 1.00 194.28 ?  99  LYS A N   1 
ATOM 439  C CA  . LYS A 1 117 ? 136.805 112.639 100.671 1.00 194.28 ?  99  LYS A CA  1 
ATOM 440  C C   . LYS A 1 117 ? 136.293 112.527 102.098 1.00 194.28 ?  99  LYS A C   1 
ATOM 441  O O   . LYS A 1 117 ? 135.367 111.764 102.371 1.00 194.28 ?  99  LYS A O   1 
ATOM 442  C CB  . LYS A 1 117 ? 135.945 113.612 99.867  1.00 194.28 ?  99  LYS A CB  1 
ATOM 443  C CG  . LYS A 1 117 ? 136.357 113.746 98.413  1.00 194.28 ?  99  LYS A CG  1 
ATOM 444  C CD  . LYS A 1 117 ? 137.434 114.802 98.242  1.00 194.28 ?  99  LYS A CD  1 
ATOM 445  C CE  . LYS A 1 117 ? 138.678 114.219 97.594  1.00 194.28 ?  99  LYS A CE  1 
ATOM 446  N NZ  . LYS A 1 117 ? 139.336 113.213 98.472  1.00 194.28 1  99  LYS A NZ  1 
ATOM 447  N N   . SER A 1 118 ? 136.890 113.285 103.011 1.00 185.78 ?  100 SER A N   1 
ATOM 448  C CA  . SER A 1 118 ? 136.495 113.207 104.414 1.00 185.78 ?  100 SER A CA  1 
ATOM 449  C C   . SER A 1 118 ? 135.016 113.506 104.587 1.00 185.78 ?  100 SER A C   1 
ATOM 450  O O   . SER A 1 118 ? 134.316 112.793 105.305 1.00 185.78 ?  100 SER A O   1 
ATOM 451  C CB  . SER A 1 118 ? 137.323 114.179 105.255 1.00 185.78 ?  100 SER A CB  1 
ATOM 452  O OG  . SER A 1 118 ? 136.860 115.510 105.101 1.00 185.78 ?  100 SER A OG  1 
ATOM 453  N N   . GLY A 1 119 ? 134.536 114.552 103.926 1.00 190.60 ?  101 GLY A N   1 
ATOM 454  C CA  . GLY A 1 119 ? 133.140 114.925 104.049 1.00 190.60 ?  101 GLY A CA  1 
ATOM 455  C C   . GLY A 1 119 ? 132.256 114.167 103.085 1.00 190.60 ?  101 GLY A C   1 
ATOM 456  O O   . GLY A 1 119 ? 132.165 114.519 101.909 1.00 190.60 ?  101 GLY A O   1 
ATOM 457  N N   . ALA A 1 120 ? 131.601 113.120 103.573 1.00 190.82 ?  102 ALA A N   1 
ATOM 458  C CA  . ALA A 1 120 ? 130.686 112.371 102.727 1.00 190.82 ?  102 ALA A CA  1 
ATOM 459  C C   . ALA A 1 120 ? 129.525 113.264 102.338 1.00 190.82 ?  102 ALA A C   1 
ATOM 460  O O   . ALA A 1 120 ? 128.943 113.923 103.199 1.00 190.82 ?  102 ALA A O   1 
ATOM 461  C CB  . ALA A 1 120 ? 130.193 111.124 103.438 1.00 190.82 ?  102 ALA A CB  1 
ATOM 462  N N   . SER A 1 121 ? 129.204 113.311 101.049 1.00 179.11 ?  103 SER A N   1 
ATOM 463  C CA  . SER A 1 121 ? 128.114 114.157 100.559 1.00 179.11 ?  103 SER A CA  1 
ATOM 464  C C   . SER A 1 121 ? 128.481 115.634 100.659 1.00 179.11 ?  103 SER A C   1 
ATOM 465  O O   . SER A 1 121 ? 127.778 116.489 100.121 1.00 179.11 ?  103 SER A O   1 
ATOM 466  C CB  . SER A 1 121 ? 126.806 113.869 101.305 1.00 179.11 ?  103 SER A CB  1 
ATOM 467  O OG  . SER A 1 121 ? 126.658 114.721 102.427 1.00 179.11 ?  103 SER A OG  1 
ATOM 468  N N   . TYR A 1 122 ? 129.584 115.935 101.337 1.00 180.86 ?  104 TYR A N   1 
ATOM 469  C CA  . TYR A 1 122 ? 130.033 117.317 101.451 1.00 180.86 ?  104 TYR A CA  1 
ATOM 470  C C   . TYR A 1 122 ? 131.326 117.499 100.682 1.00 180.86 ?  104 TYR A C   1 
ATOM 471  O O   . TYR A 1 122 ? 131.315 118.003 99.558  1.00 180.86 ?  104 TYR A O   1 
ATOM 472  C CB  . TYR A 1 122 ? 130.228 117.716 102.912 1.00 180.86 ?  104 TYR A CB  1 
ATOM 473  C CG  . TYR A 1 122 ? 130.508 119.190 103.088 1.00 180.86 ?  104 TYR A CG  1 
ATOM 474  C CD1 . TYR A 1 122 ? 129.633 120.144 102.588 1.00 180.86 ?  104 TYR A CD1 1 
ATOM 475  C CD2 . TYR A 1 122 ? 131.652 119.628 103.741 1.00 180.86 ?  104 TYR A CD2 1 
ATOM 476  C CE1 . TYR A 1 122 ? 129.884 121.493 102.740 1.00 180.86 ?  104 TYR A CE1 1 
ATOM 477  C CE2 . TYR A 1 122 ? 131.912 120.977 103.898 1.00 180.86 ?  104 TYR A CE2 1 
ATOM 478  C CZ  . TYR A 1 122 ? 131.024 121.904 103.395 1.00 180.86 ?  104 TYR A CZ  1 
ATOM 479  O OH  . TYR A 1 122 ? 131.278 123.248 103.546 1.00 180.86 ?  104 TYR A OH  1 
ATOM 480  N N   . ALA A 1 123 ? 132.446 117.094 101.275 1.00 178.84 ?  105 ALA A N   1 
ATOM 481  C CA  . ALA A 1 123 ? 133.704 117.169 100.555 1.00 178.84 ?  105 ALA A CA  1 
ATOM 482  C C   . ALA A 1 123 ? 133.555 116.580 99.169  1.00 178.84 ?  105 ALA A C   1 
ATOM 483  O O   . ALA A 1 123 ? 134.298 116.945 98.255  1.00 178.84 ?  105 ALA A O   1 
ATOM 484  C CB  . ALA A 1 123 ? 134.802 116.446 101.325 1.00 178.84 ?  105 ALA A CB  1 
ATOM 485  N N   . TYR A 1 124 ? 132.598 115.675 98.994  1.00 184.20 ?  106 TYR A N   1 
ATOM 486  C CA  . TYR A 1 124 ? 132.362 115.105 97.678  1.00 184.20 ?  106 TYR A CA  1 
ATOM 487  C C   . TYR A 1 124 ? 131.969 116.189 96.691  1.00 184.20 ?  106 TYR A C   1 
ATOM 488  O O   . TYR A 1 124 ? 132.649 116.406 95.682  1.00 184.20 ?  106 TYR A O   1 
ATOM 489  C CB  . TYR A 1 124 ? 131.279 114.037 97.763  1.00 184.20 ?  106 TYR A CB  1 
ATOM 490  C CG  . TYR A 1 124 ? 131.637 112.876 98.651  1.00 184.20 ?  106 TYR A CG  1 
ATOM 491  C CD1 . TYR A 1 124 ? 132.917 112.728 99.152  1.00 184.20 ?  106 TYR A CD1 1 
ATOM 492  C CD2 . TYR A 1 124 ? 130.699 111.916 98.972  1.00 184.20 ?  106 TYR A CD2 1 
ATOM 493  C CE1 . TYR A 1 124 ? 133.246 111.666 99.960  1.00 184.20 ?  106 TYR A CE1 1 
ATOM 494  C CE2 . TYR A 1 124 ? 131.017 110.852 99.780  1.00 184.20 ?  106 TYR A CE2 1 
ATOM 495  C CZ  . TYR A 1 124 ? 132.292 110.729 100.271 1.00 184.20 ?  106 TYR A CZ  1 
ATOM 496  O OH  . TYR A 1 124 ? 132.616 109.664 101.076 1.00 184.20 ?  106 TYR A OH  1 
ATOM 497  N N   . ILE A 1 125 ? 130.875 116.887 96.979  1.00 182.77 ?  107 ILE A N   1 
ATOM 498  C CA  . ILE A 1 125 ? 130.475 118.021 96.160  1.00 182.77 ?  107 ILE A CA  1 
ATOM 499  C C   . ILE A 1 125 ? 131.621 119.003 96.021  1.00 182.77 ?  107 ILE A C   1 
ATOM 500  O O   . ILE A 1 125 ? 131.861 119.556 94.941  1.00 182.77 ?  107 ILE A O   1 
ATOM 501  C CB  . ILE A 1 125 ? 129.239 118.691 96.773  1.00 182.77 ?  107 ILE A CB  1 
ATOM 502  C CG1 . ILE A 1 125 ? 128.057 117.740 96.700  1.00 182.77 ?  107 ILE A CG1 1 
ATOM 503  C CG2 . ILE A 1 125 ? 128.938 119.992 96.067  1.00 182.77 ?  107 ILE A CG2 1 
ATOM 504  C CD1 . ILE A 1 125 ? 127.693 117.397 95.295  1.00 182.77 ?  107 ILE A CD1 1 
ATOM 505  N N   . LEU A 1 126 ? 132.348 119.232 97.111  1.00 201.27 ?  108 LEU A N   1 
ATOM 506  C CA  . LEU A 1 126 ? 133.430 120.204 97.096  1.00 201.27 ?  108 LEU A CA  1 
ATOM 507  C C   . LEU A 1 126 ? 134.447 119.868 96.017  1.00 201.27 ?  108 LEU A C   1 
ATOM 508  O O   . LEU A 1 126 ? 134.635 120.626 95.061  1.00 201.27 ?  108 LEU A O   1 
ATOM 509  C CB  . LEU A 1 126 ? 134.102 120.245 98.461  1.00 201.27 ?  108 LEU A CB  1 
ATOM 510  C CG  . LEU A 1 126 ? 135.210 121.287 98.541  1.00 201.27 ?  108 LEU A CG  1 
ATOM 511  C CD1 . LEU A 1 126 ? 134.725 122.604 97.964  1.00 201.27 ?  108 LEU A CD1 1 
ATOM 512  C CD2 . LEU A 1 126 ? 135.673 121.460 99.971  1.00 201.27 ?  108 LEU A CD2 1 
ATOM 513  N N   . GLU A 1 127 ? 135.111 118.722 96.161  1.00 211.12 ?  109 GLU A N   1 
ATOM 514  C CA  . GLU A 1 127 ? 136.047 118.262 95.145  1.00 211.12 ?  109 GLU A CA  1 
ATOM 515  C C   . GLU A 1 127 ? 135.406 118.278 93.770  1.00 211.12 ?  109 GLU A C   1 
ATOM 516  O O   . GLU A 1 127 ? 136.061 118.597 92.772  1.00 211.12 ?  109 GLU A O   1 
ATOM 517  C CB  . GLU A 1 127 ? 136.533 116.856 95.490  1.00 211.12 ?  109 GLU A CB  1 
ATOM 518  C CG  . GLU A 1 127 ? 137.107 116.087 94.318  1.00 211.12 ?  109 GLU A CG  1 
ATOM 519  C CD  . GLU A 1 127 ? 138.596 116.286 94.162  1.00 211.12 ?  109 GLU A CD  1 
ATOM 520  O OE1 . GLU A 1 127 ? 139.155 117.153 94.864  1.00 211.12 ?  109 GLU A OE1 1 
ATOM 521  O OE2 . GLU A 1 127 ? 139.212 115.569 93.346  1.00 211.12 -1 109 GLU A OE2 1 
ATOM 522  N N   . ALA A 1 128 ? 134.115 117.957 93.702  1.00 207.81 ?  110 ALA A N   1 
ATOM 523  C CA  . ALA A 1 128 ? 133.430 117.955 92.420  1.00 207.81 ?  110 ALA A CA  1 
ATOM 524  C C   . ALA A 1 128 ? 133.461 119.331 91.772  1.00 207.81 ?  110 ALA A C   1 
ATOM 525  O O   . ALA A 1 128 ? 133.765 119.455 90.581  1.00 207.81 ?  110 ALA A O   1 
ATOM 526  C CB  . ALA A 1 128 ? 131.992 117.478 92.599  1.00 207.81 ?  110 ALA A CB  1 
ATOM 527  N N   . PHE A 1 129 ? 133.162 120.364 92.522  1.00 198.26 ?  111 PHE A N   1 
ATOM 528  C CA  . PHE A 1 129 ? 133.046 121.671 91.891  1.00 198.26 ?  111 PHE A CA  1 
ATOM 529  C C   . PHE A 1 129 ? 133.825 122.758 92.604  1.00 198.26 ?  111 PHE A C   1 
ATOM 530  O O   . PHE A 1 129 ? 134.255 123.715 91.958  1.00 198.26 ?  111 PHE A O   1 
ATOM 531  C CB  . PHE A 1 129 ? 131.575 122.038 91.803  1.00 198.26 ?  111 PHE A CB  1 
ATOM 532  C CG  . PHE A 1 129 ? 130.707 120.885 91.422  1.00 198.26 ?  111 PHE A CG  1 
ATOM 533  C CD1 . PHE A 1 129 ? 130.764 120.359 90.146  1.00 198.26 ?  111 PHE A CD1 1 
ATOM 534  C CD2 . PHE A 1 129 ? 129.869 120.295 92.344  1.00 198.26 ?  111 PHE A CD2 1 
ATOM 535  C CE1 . PHE A 1 129 ? 129.980 119.284 89.789  1.00 198.26 ?  111 PHE A CE1 1 
ATOM 536  C CE2 . PHE A 1 129 ? 129.079 119.220 91.990  1.00 198.26 ?  111 PHE A CE2 1 
ATOM 537  C CZ  . PHE A 1 129 ? 129.137 118.715 90.711  1.00 198.26 ?  111 PHE A CZ  1 
ATOM 538  N N   . GLY A 1 130 ? 134.021 122.635 93.911  1.00 207.97 ?  112 GLY A N   1 
ATOM 539  C CA  . GLY A 1 130 ? 134.757 123.656 94.635  1.00 207.97 ?  112 GLY A CA  1 
ATOM 540  C C   . GLY A 1 130 ? 134.078 125.004 94.620  1.00 207.97 ?  112 GLY A C   1 
ATOM 541  O O   . GLY A 1 130 ? 134.752 126.040 94.650  1.00 207.97 ?  112 GLY A O   1 
ATOM 542  N N   . GLY A 1 131 ? 132.754 125.016 94.572  1.00 187.77 ?  113 GLY A N   1 
ATOM 543  C CA  . GLY A 1 131 ? 132.051 126.274 94.507  1.00 187.77 ?  113 GLY A CA  1 
ATOM 544  C C   . GLY A 1 131 ? 131.126 126.487 95.679  1.00 187.77 ?  113 GLY A C   1 
ATOM 545  O O   . GLY A 1 131 ? 131.086 125.682 96.613  1.00 187.77 ?  113 GLY A O   1 
ATOM 546  N N   . PHE A 1 132 ? 130.367 127.580 95.625  1.00 195.97 ?  114 PHE A N   1 
ATOM 547  C CA  . PHE A 1 132 ? 129.380 127.854 96.656  1.00 195.97 ?  114 PHE A CA  1 
ATOM 548  C C   . PHE A 1 132 ? 128.411 126.705 96.839  1.00 195.97 ?  114 PHE A C   1 
ATOM 549  O O   . PHE A 1 132 ? 127.760 126.631 97.880  1.00 195.97 ?  114 PHE A O   1 
ATOM 550  C CB  . PHE A 1 132 ? 128.601 129.113 96.312  1.00 195.97 ?  114 PHE A CB  1 
ATOM 551  C CG  . PHE A 1 132 ? 128.213 129.199 94.879  1.00 195.97 ?  114 PHE A CG  1 
ATOM 552  C CD1 . PHE A 1 132 ? 129.025 129.849 93.968  1.00 195.97 ?  114 PHE A CD1 1 
ATOM 553  C CD2 . PHE A 1 132 ? 127.040 128.626 94.436  1.00 195.97 ?  114 PHE A CD2 1 
ATOM 554  C CE1 . PHE A 1 132 ? 128.669 129.928 92.638  1.00 195.97 ?  114 PHE A CE1 1 
ATOM 555  C CE2 . PHE A 1 132 ? 126.676 128.703 93.110  1.00 195.97 ?  114 PHE A CE2 1 
ATOM 556  C CZ  . PHE A 1 132 ? 127.491 129.354 92.208  1.00 195.97 ?  114 PHE A CZ  1 
ATOM 557  N N   . LEU A 1 133 ? 128.287 125.828 95.844  1.00 182.40 ?  115 LEU A N   1 
ATOM 558  C CA  . LEU A 1 133 ? 127.426 124.661 95.972  1.00 182.40 ?  115 LEU A CA  1 
ATOM 559  C C   . LEU A 1 133 ? 127.669 123.951 97.289  1.00 182.40 ?  115 LEU A C   1 
ATOM 560  O O   . LEU A 1 133 ? 126.733 123.684 98.050  1.00 182.40 ?  115 LEU A O   1 
ATOM 561  C CB  . LEU A 1 133 ? 127.679 123.707 94.813  1.00 182.40 ?  115 LEU A CB  1 
ATOM 562  C CG  . LEU A 1 133 ? 127.909 124.412 93.488  1.00 182.40 ?  115 LEU A CG  1 
ATOM 563  C CD1 . LEU A 1 133 ? 128.315 123.416 92.425  1.00 182.40 ?  115 LEU A CD1 1 
ATOM 564  C CD2 . LEU A 1 133 ? 126.646 125.140 93.089  1.00 182.40 ?  115 LEU A CD2 1 
ATOM 565  N N   . ALA A 1 134 ? 128.928 123.628 97.566  1.00 189.20 ?  116 ALA A N   1 
ATOM 566  C CA  . ALA A 1 134 ? 129.256 122.975 98.822  1.00 189.20 ?  116 ALA A CA  1 
ATOM 567  C C   . ALA A 1 134 ? 128.780 123.803 100.001 1.00 189.20 ?  116 ALA A C   1 
ATOM 568  O O   . ALA A 1 134 ? 128.271 123.260 100.989 1.00 189.20 ?  116 ALA A O   1 
ATOM 569  C CB  . ALA A 1 134 ? 130.760 122.735 98.902  1.00 189.20 ?  116 ALA A CB  1 
ATOM 570  N N   . PHE A 1 135 ? 128.931 125.123 99.915  1.00 196.94 ?  117 PHE A N   1 
ATOM 571  C CA  . PHE A 1 135 ? 128.510 125.976 101.015 1.00 196.94 ?  117 PHE A CA  1 
ATOM 572  C C   . PHE A 1 135 ? 127.011 125.872 101.235 1.00 196.94 ?  117 PHE A C   1 
ATOM 573  O O   . PHE A 1 135 ? 126.540 125.802 102.371 1.00 196.94 ?  117 PHE A O   1 
ATOM 574  C CB  . PHE A 1 135 ? 128.902 127.423 100.742 1.00 196.94 ?  117 PHE A CB  1 
ATOM 575  C CG  . PHE A 1 135 ? 128.170 128.406 101.592 1.00 196.94 ?  117 PHE A CG  1 
ATOM 576  C CD1 . PHE A 1 135 ? 128.648 128.742 102.838 1.00 196.94 ?  117 PHE A CD1 1 
ATOM 577  C CD2 . PHE A 1 135 ? 126.996 128.985 101.154 1.00 196.94 ?  117 PHE A CD2 1 
ATOM 578  C CE1 . PHE A 1 135 ? 127.978 129.640 103.626 1.00 196.94 ?  117 PHE A CE1 1 
ATOM 579  C CE2 . PHE A 1 135 ? 126.319 129.877 101.944 1.00 196.94 ?  117 PHE A CE2 1 
ATOM 580  C CZ  . PHE A 1 135 ? 126.811 130.209 103.178 1.00 196.94 ?  117 PHE A CZ  1 
ATOM 581  N N   . ILE A 1 136 ? 126.246 125.896 100.151 1.00 192.03 ?  118 ILE A N   1 
ATOM 582  C CA  . ILE A 1 136 ? 124.802 125.787 100.264 1.00 192.03 ?  118 ILE A CA  1 
ATOM 583  C C   . ILE A 1 136 ? 124.435 124.439 100.843 1.00 192.03 ?  118 ILE A C   1 
ATOM 584  O O   . ILE A 1 136 ? 123.462 124.304 101.593 1.00 192.03 ?  118 ILE A O   1 
ATOM 585  C CB  . ILE A 1 136 ? 124.156 126.002 98.891  1.00 192.03 ?  118 ILE A CB  1 
ATOM 586  C CG1 . ILE A 1 136 ? 124.705 127.275 98.259  1.00 192.03 ?  118 ILE A CG1 1 
ATOM 587  C CG2 . ILE A 1 136 ? 122.660 126.081 99.027  1.00 192.03 ?  118 ILE A CG2 1 
ATOM 588  C CD1 . ILE A 1 136 ? 124.890 127.175 96.769  1.00 192.03 ?  118 ILE A CD1 1 
ATOM 589  N N   . ARG A 1 137 ? 125.196 123.416 100.484 1.00 196.54 ?  119 ARG A N   1 
ATOM 590  C CA  . ARG A 1 137 ? 124.977 122.108 101.071 1.00 196.54 ?  119 ARG A CA  1 
ATOM 591  C C   . ARG A 1 137 ? 125.131 122.177 102.573 1.00 196.54 ?  119 ARG A C   1 
ATOM 592  O O   . ARG A 1 137 ? 124.245 121.755 103.325 1.00 196.54 ?  119 ARG A O   1 
ATOM 593  C CB  . ARG A 1 137 ? 125.951 121.110 100.465 1.00 196.54 ?  119 ARG A CB  1 
ATOM 594  C CG  . ARG A 1 137 ? 125.755 120.913 98.977  1.00 196.54 ?  119 ARG A CG  1 
ATOM 595  C CD  . ARG A 1 137 ? 124.380 120.326 98.645  1.00 196.54 ?  119 ARG A CD  1 
ATOM 596  N NE  . ARG A 1 137 ? 123.312 121.318 98.708  1.00 196.54 ?  119 ARG A NE  1 
ATOM 597  C CZ  . ARG A 1 137 ? 122.020 121.030 98.660  1.00 196.54 ?  119 ARG A CZ  1 
ATOM 598  N NH1 . ARG A 1 137 ? 121.623 119.781 98.537  1.00 196.54 1  119 ARG A NH1 1 
ATOM 599  N NH2 . ARG A 1 137 ? 121.123 121.999 98.730  1.00 196.54 ?  119 ARG A NH2 1 
ATOM 600  N N   . LEU A 1 138 ? 126.255 122.723 103.019 1.00 196.30 ?  120 LEU A N   1 
ATOM 601  C CA  . LEU A 1 138 ? 126.465 122.968 104.436 1.00 196.30 ?  120 LEU A CA  1 
ATOM 602  C C   . LEU A 1 138 ? 125.277 123.690 105.040 1.00 196.30 ?  120 LEU A C   1 
ATOM 603  O O   . LEU A 1 138 ? 124.746 123.290 106.080 1.00 196.30 ?  120 LEU A O   1 
ATOM 604  C CB  . LEU A 1 138 ? 127.729 123.794 104.628 1.00 196.30 ?  120 LEU A CB  1 
ATOM 605  C CG  . LEU A 1 138 ? 128.327 123.699 106.016 1.00 196.30 ?  120 LEU A CG  1 
ATOM 606  C CD1 . LEU A 1 138 ? 128.415 122.249 106.404 1.00 196.30 ?  120 LEU A CD1 1 
ATOM 607  C CD2 . LEU A 1 138 ? 129.693 124.336 106.021 1.00 196.30 ?  120 LEU A CD2 1 
ATOM 608  N N   . TRP A 1 139 ? 124.840 124.755 104.380 1.00 209.62 ?  121 TRP A N   1 
ATOM 609  C CA  . TRP A 1 139 ? 123.794 125.604 104.925 1.00 209.62 ?  121 TRP A CA  1 
ATOM 610  C C   . TRP A 1 139 ? 122.517 124.815 105.130 1.00 209.62 ?  121 TRP A C   1 
ATOM 611  O O   . TRP A 1 139 ? 122.074 124.591 106.261 1.00 209.62 ?  121 TRP A O   1 
ATOM 612  C CB  . TRP A 1 139 ? 123.553 126.773 103.977 1.00 209.62 ?  121 TRP A CB  1 
ATOM 613  C CG  . TRP A 1 139 ? 122.436 127.644 104.383 1.00 209.62 ?  121 TRP A CG  1 
ATOM 614  C CD1 . TRP A 1 139 ? 121.113 127.331 104.394 1.00 209.62 ?  121 TRP A CD1 1 
ATOM 615  C CD2 . TRP A 1 139 ? 122.533 128.991 104.832 1.00 209.62 ?  121 TRP A CD2 1 
ATOM 616  N NE1 . TRP A 1 139 ? 120.379 128.398 104.834 1.00 209.62 ?  121 TRP A NE1 1 
ATOM 617  C CE2 . TRP A 1 139 ? 121.231 129.432 105.112 1.00 209.62 ?  121 TRP A CE2 1 
ATOM 618  C CE3 . TRP A 1 139 ? 123.598 129.868 105.026 1.00 209.62 ?  121 TRP A CE3 1 
ATOM 619  C CZ2 . TRP A 1 139 ? 120.963 130.712 105.575 1.00 209.62 ?  121 TRP A CZ2 1 
ATOM 620  C CZ3 . TRP A 1 139 ? 123.331 131.135 105.484 1.00 209.62 ?  121 TRP A CZ3 1 
ATOM 621  C CH2 . TRP A 1 139 ? 122.025 131.548 105.752 1.00 209.62 ?  121 TRP A CH2 1 
ATOM 622  N N   . THR A 1 140 ? 121.926 124.363 104.033 1.00 190.28 ?  122 THR A N   1 
ATOM 623  C CA  . THR A 1 140 ? 120.661 123.658 104.111 1.00 190.28 ?  122 THR A CA  1 
ATOM 624  C C   . THR A 1 140 ? 120.757 122.442 105.005 1.00 190.28 ?  122 THR A C   1 
ATOM 625  O O   . THR A 1 140 ? 119.760 122.044 105.614 1.00 190.28 ?  122 THR A O   1 
ATOM 626  C CB  . THR A 1 140 ? 120.219 123.256 102.719 1.00 190.28 ?  122 THR A CB  1 
ATOM 627  O OG1 . THR A 1 140 ? 121.251 122.469 102.118 1.00 190.28 ?  122 THR A OG1 1 
ATOM 628  C CG2 . THR A 1 140 ? 119.990 124.491 101.889 1.00 190.28 ?  122 THR A CG2 1 
ATOM 629  N N   . SER A 1 141 ? 121.937 121.837 105.107 1.00 189.75 ?  123 SER A N   1 
ATOM 630  C CA  . SER A 1 141 ? 122.116 120.805 106.112 1.00 189.75 ?  123 SER A CA  1 
ATOM 631  C C   . SER A 1 141 ? 121.889 121.383 107.494 1.00 189.75 ?  123 SER A C   1 
ATOM 632  O O   . SER A 1 141 ? 121.079 120.868 108.270 1.00 189.75 ?  123 SER A O   1 
ATOM 633  C CB  . SER A 1 141 ? 123.513 120.202 106.002 1.00 189.75 ?  123 SER A CB  1 
ATOM 634  O OG  . SER A 1 141 ? 123.694 119.556 104.756 1.00 189.75 ?  123 SER A OG  1 
ATOM 635  N N   . LEU A 1 142 ? 122.546 122.500 107.787 1.00 201.90 ?  124 LEU A N   1 
ATOM 636  C CA  . LEU A 1 142 ? 122.566 123.006 109.150 1.00 201.90 ?  124 LEU A CA  1 
ATOM 637  C C   . LEU A 1 142 ? 121.211 123.547 109.572 1.00 201.90 ?  124 LEU A C   1 
ATOM 638  O O   . LEU A 1 142 ? 120.717 123.221 110.654 1.00 201.90 ?  124 LEU A O   1 
ATOM 639  C CB  . LEU A 1 142 ? 123.626 124.084 109.291 1.00 201.90 ?  124 LEU A CB  1 
ATOM 640  C CG  . LEU A 1 142 ? 123.896 124.433 110.746 1.00 201.90 ?  124 LEU A CG  1 
ATOM 641  C CD1 . LEU A 1 142 ? 123.971 123.170 111.572 1.00 201.90 ?  124 LEU A CD1 1 
ATOM 642  C CD2 . LEU A 1 142 ? 125.184 125.206 110.850 1.00 201.90 ?  124 LEU A CD2 1 
ATOM 643  N N   . LEU A 1 143 ? 120.602 124.381 108.746 1.00 203.03 ?  125 LEU A N   1 
ATOM 644  C CA  . LEU A 1 143 ? 119.368 125.023 109.157 1.00 203.03 ?  125 LEU A CA  1 
ATOM 645  C C   . LEU A 1 143 ? 118.175 124.089 109.111 1.00 203.03 ?  125 LEU A C   1 
ATOM 646  O O   . LEU A 1 143 ? 117.156 124.383 109.737 1.00 203.03 ?  125 LEU A O   1 
ATOM 647  C CB  . LEU A 1 143 ? 119.090 126.236 108.282 1.00 203.03 ?  125 LEU A CB  1 
ATOM 648  C CG  . LEU A 1 143 ? 119.965 127.441 108.593 1.00 203.03 ?  125 LEU A CG  1 
ATOM 649  C CD1 . LEU A 1 143 ? 121.269 127.361 107.833 1.00 203.03 ?  125 LEU A CD1 1 
ATOM 650  C CD2 . LEU A 1 143 ? 119.232 128.714 108.252 1.00 203.03 ?  125 LEU A CD2 1 
ATOM 651  N N   . ILE A 1 144 ? 118.266 122.980 108.390 1.00 186.80 ?  126 ILE A N   1 
ATOM 652  C CA  . ILE A 1 144 ? 117.081 122.170 108.158 1.00 186.80 ?  126 ILE A CA  1 
ATOM 653  C C   . ILE A 1 144 ? 117.271 120.740 108.617 1.00 186.80 ?  126 ILE A C   1 
ATOM 654  O O   . ILE A 1 144 ? 116.586 120.269 109.530 1.00 186.80 ?  126 ILE A O   1 
ATOM 655  C CB  . ILE A 1 144 ? 116.708 122.177 106.673 1.00 186.80 ?  126 ILE A CB  1 
ATOM 656  C CG1 . ILE A 1 144 ? 116.276 123.572 106.260 1.00 186.80 ?  126 ILE A CG1 1 
ATOM 657  C CG2 . ILE A 1 144 ? 115.609 121.189 106.424 1.00 186.80 ?  126 ILE A CG2 1 
ATOM 658  C CD1 . ILE A 1 144 ? 115.281 124.168 107.192 1.00 186.80 ?  126 ILE A CD1 1 
ATOM 659  N N   . ILE A 1 145 ? 118.217 120.055 107.994 1.00 189.32 ?  127 ILE A N   1 
ATOM 660  C CA  . ILE A 1 145 ? 118.209 118.604 107.935 1.00 189.32 ?  127 ILE A CA  1 
ATOM 661  C C   . ILE A 1 145 ? 118.289 117.970 109.317 1.00 189.32 ?  127 ILE A C   1 
ATOM 662  O O   . ILE A 1 145 ? 117.333 117.339 109.781 1.00 189.32 ?  127 ILE A O   1 
ATOM 663  C CB  . ILE A 1 145 ? 119.359 118.139 107.036 1.00 189.32 ?  127 ILE A CB  1 
ATOM 664  C CG1 . ILE A 1 145 ? 119.224 118.803 105.676 1.00 189.32 ?  127 ILE A CG1 1 
ATOM 665  C CG2 . ILE A 1 145 ? 119.334 116.660 106.877 1.00 189.32 ?  127 ILE A CG2 1 
ATOM 666  C CD1 . ILE A 1 145 ? 120.088 118.183 104.633 1.00 189.32 ?  127 ILE A CD1 1 
ATOM 667  N N   . GLU A 1 146 ? 119.396 118.147 109.997 1.00 200.54 ?  128 GLU A N   1 
ATOM 668  C CA  . GLU A 1 146 ? 119.461 117.474 111.282 1.00 200.54 ?  128 GLU A CA  1 
ATOM 669  C C   . GLU A 1 146 ? 118.578 118.134 112.336 1.00 200.54 ?  128 GLU A C   1 
ATOM 670  O O   . GLU A 1 146 ? 118.094 117.422 113.223 1.00 200.54 ?  128 GLU A O   1 
ATOM 671  C CB  . GLU A 1 146 ? 120.899 117.347 111.783 1.00 200.54 ?  128 GLU A CB  1 
ATOM 672  C CG  . GLU A 1 146 ? 121.601 118.627 112.052 1.00 200.54 ?  128 GLU A CG  1 
ATOM 673  C CD  . GLU A 1 146 ? 121.838 119.398 110.791 1.00 200.54 ?  128 GLU A CD  1 
ATOM 674  O OE1 . GLU A 1 146 ? 121.819 118.775 109.711 1.00 200.54 ?  128 GLU A OE1 1 
ATOM 675  O OE2 . GLU A 1 146 ? 122.011 120.624 110.875 1.00 200.54 -1 128 GLU A OE2 1 
ATOM 676  N N   . PRO A 1 147 ? 118.341 119.453 112.324 1.00 172.87 ?  129 PRO A N   1 
ATOM 677  C CA  . PRO A 1 147 ? 117.365 119.972 113.289 1.00 172.87 ?  129 PRO A CA  1 
ATOM 678  C C   . PRO A 1 147 ? 116.044 119.251 113.184 1.00 172.87 ?  129 PRO A C   1 
ATOM 679  O O   . PRO A 1 147 ? 115.528 118.749 114.190 1.00 172.87 ?  129 PRO A O   1 
ATOM 680  C CB  . PRO A 1 147 ? 117.250 121.449 112.914 1.00 172.87 ?  129 PRO A CB  1 
ATOM 681  C CG  . PRO A 1 147 ? 118.508 121.759 112.307 1.00 172.87 ?  129 PRO A CG  1 
ATOM 682  C CD  . PRO A 1 147 ? 118.895 120.559 111.530 1.00 172.87 ?  129 PRO A CD  1 
ATOM 683  N N   . THR A 1 148 ? 115.497 119.150 111.978 1.00 178.30 ?  130 THR A N   1 
ATOM 684  C CA  . THR A 1 148 ? 114.213 118.488 111.859 1.00 178.30 ?  130 THR A CA  1 
ATOM 685  C C   . THR A 1 148 ? 114.326 117.011 112.177 1.00 178.30 ?  130 THR A C   1 
ATOM 686  O O   . THR A 1 148 ? 113.411 116.443 112.776 1.00 178.30 ?  130 THR A O   1 
ATOM 687  C CB  . THR A 1 148 ? 113.621 118.699 110.472 1.00 178.30 ?  130 THR A CB  1 
ATOM 688  O OG1 . THR A 1 148 ? 112.334 118.079 110.418 1.00 178.30 ?  130 THR A OG1 1 
ATOM 689  C CG2 . THR A 1 148 ? 114.480 118.086 109.426 1.00 178.30 ?  130 THR A CG2 1 
ATOM 690  N N   . SER A 1 149 ? 115.444 116.379 111.831 1.00 179.10 ?  131 SER A N   1 
ATOM 691  C CA  . SER A 1 149 ? 115.590 114.963 112.139 1.00 179.10 ?  131 SER A CA  1 
ATOM 692  C C   . SER A 1 149 ? 115.509 114.723 113.638 1.00 179.10 ?  131 SER A C   1 
ATOM 693  O O   . SER A 1 149 ? 114.728 113.887 114.117 1.00 179.10 ?  131 SER A O   1 
ATOM 694  C CB  . SER A 1 149 ? 116.919 114.456 111.607 1.00 179.10 ?  131 SER A CB  1 
ATOM 695  O OG  . SER A 1 149 ? 117.914 114.649 112.590 1.00 179.10 ?  131 SER A OG  1 
ATOM 696  N N   . GLN A 1 150 ? 116.328 115.443 114.393 1.00 172.99 ?  132 GLN A N   1 
ATOM 697  C CA  . GLN A 1 150 ? 116.359 115.242 115.829 1.00 172.99 ?  132 GLN A CA  1 
ATOM 698  C C   . GLN A 1 150 ? 115.032 115.624 116.460 1.00 172.99 ?  132 GLN A C   1 
ATOM 699  O O   . GLN A 1 150 ? 114.549 114.934 117.367 1.00 172.99 ?  132 GLN A O   1 
ATOM 700  C CB  . GLN A 1 150 ? 117.508 116.036 116.426 1.00 172.99 ?  132 GLN A CB  1 
ATOM 701  C CG  . GLN A 1 150 ? 118.811 115.690 115.772 1.00 172.99 ?  132 GLN A CG  1 
ATOM 702  C CD  . GLN A 1 150 ? 119.964 116.480 116.319 1.00 172.99 ?  132 GLN A CD  1 
ATOM 703  O OE1 . GLN A 1 150 ? 119.967 117.708 116.277 1.00 172.99 ?  132 GLN A OE1 1 
ATOM 704  N NE2 . GLN A 1 150 ? 120.962 115.779 116.836 1.00 172.99 ?  132 GLN A NE2 1 
ATOM 705  N N   . ALA A 1 151 ? 114.427 116.716 115.998 1.00 160.68 ?  133 ALA A N   1 
ATOM 706  C CA  . ALA A 1 151 ? 113.103 117.059 116.487 1.00 160.68 ?  133 ALA A CA  1 
ATOM 707  C C   . ALA A 1 151 ? 112.148 115.900 116.288 1.00 160.68 ?  133 ALA A C   1 
ATOM 708  O O   . ALA A 1 151 ? 111.383 115.547 117.193 1.00 160.68 ?  133 ALA A O   1 
ATOM 709  C CB  . ALA A 1 151 ? 112.586 118.301 115.772 1.00 160.68 ?  133 ALA A CB  1 
ATOM 710  N N   . ILE A 1 152 ? 112.203 115.280 115.115 1.00 172.63 ?  134 ILE A N   1 
ATOM 711  C CA  . ILE A 1 152 ? 111.328 114.158 114.823 1.00 172.63 ?  134 ILE A CA  1 
ATOM 712  C C   . ILE A 1 152 ? 111.522 113.064 115.855 1.00 172.63 ?  134 ILE A C   1 
ATOM 713  O O   . ILE A 1 152 ? 110.576 112.665 116.543 1.00 172.63 ?  134 ILE A O   1 
ATOM 714  C CB  . ILE A 1 152 ? 111.585 113.643 113.403 1.00 172.63 ?  134 ILE A CB  1 
ATOM 715  C CG1 . ILE A 1 152 ? 110.879 114.546 112.406 1.00 172.63 ?  134 ILE A CG1 1 
ATOM 716  C CG2 . ILE A 1 152 ? 111.098 112.236 113.271 1.00 172.63 ?  134 ILE A CG2 1 
ATOM 717  C CD1 . ILE A 1 152 ? 111.371 114.387 111.011 1.00 172.63 ?  134 ILE A CD1 1 
ATOM 718  N N   . ILE A 1 153 ? 112.758 112.588 115.992 1.00 156.11 ?  135 ILE A N   1 
ATOM 719  C CA  . ILE A 1 153 ? 113.014 111.486 116.914 1.00 156.11 ?  135 ILE A CA  1 
ATOM 720  C C   . ILE A 1 153 ? 112.510 111.819 118.305 1.00 156.11 ?  135 ILE A C   1 
ATOM 721  O O   . ILE A 1 153 ? 111.845 111.001 118.954 1.00 156.11 ?  135 ILE A O   1 
ATOM 722  C CB  . ILE A 1 153 ? 114.505 111.127 116.939 1.00 156.11 ?  135 ILE A CB  1 
ATOM 723  C CG1 . ILE A 1 153 ? 114.886 110.403 115.661 1.00 156.11 ?  135 ILE A CG1 1 
ATOM 724  C CG2 . ILE A 1 153 ? 114.831 110.286 118.146 1.00 156.11 ?  135 ILE A CG2 1 
ATOM 725  C CD1 . ILE A 1 153 ? 116.355 110.170 115.541 1.00 156.11 ?  135 ILE A CD1 1 
ATOM 726  N N   . ALA A 1 154 ? 112.812 113.020 118.787 1.00 155.23 ?  136 ALA A N   1 
ATOM 727  C CA  . ALA A 1 154 ? 112.392 113.384 120.131 1.00 155.23 ?  136 ALA A CA  1 
ATOM 728  C C   . ALA A 1 154 ? 110.879 113.339 120.256 1.00 155.23 ?  136 ALA A C   1 
ATOM 729  O O   . ALA A 1 154 ? 110.337 112.914 121.283 1.00 155.23 ?  136 ALA A O   1 
ATOM 730  C CB  . ALA A 1 154 ? 112.916 114.768 120.484 1.00 155.23 ?  136 ALA A CB  1 
ATOM 731  N N   . ILE A 1 155 ? 110.178 113.785 119.220 1.00 155.02 ?  137 ILE A N   1 
ATOM 732  C CA  . ILE A 1 155 ? 108.727 113.717 119.261 1.00 155.02 ?  137 ILE A CA  1 
ATOM 733  C C   . ILE A 1 155 ? 108.276 112.277 119.388 1.00 155.02 ?  137 ILE A C   1 
ATOM 734  O O   . ILE A 1 155 ? 107.386 111.957 120.184 1.00 155.02 ?  137 ILE A O   1 
ATOM 735  C CB  . ILE A 1 155 ? 108.124 114.382 118.019 1.00 155.02 ?  137 ILE A CB  1 
ATOM 736  C CG1 . ILE A 1 155 ? 108.427 115.867 118.031 1.00 155.02 ?  137 ILE A CG1 1 
ATOM 737  C CG2 . ILE A 1 155 ? 106.644 114.183 118.006 1.00 155.02 ?  137 ILE A CG2 1 
ATOM 738  C CD1 . ILE A 1 155 ? 107.677 116.625 116.985 1.00 155.02 ?  137 ILE A CD1 1 
ATOM 739  N N   . THR A 1 156 ? 108.872 111.388 118.595 1.00 157.19 ?  138 THR A N   1 
ATOM 740  C CA  . THR A 1 156 ? 108.498 109.981 118.684 1.00 157.19 ?  138 THR A CA  1 
ATOM 741  C C   . THR A 1 156 ? 108.679 109.478 120.097 1.00 157.19 ?  138 THR A C   1 
ATOM 742  O O   . THR A 1 156 ? 107.849 108.726 120.615 1.00 157.19 ?  138 THR A O   1 
ATOM 743  C CB  . THR A 1 156 ? 109.348 109.120 117.767 1.00 157.19 ?  138 THR A CB  1 
ATOM 744  O OG1 . THR A 1 156 ? 110.533 108.746 118.472 1.00 157.19 ?  138 THR A OG1 1 
ATOM 745  C CG2 . THR A 1 156 ? 109.737 109.878 116.551 1.00 157.19 ?  138 THR A CG2 1 
ATOM 746  N N   . PHE A 1 157 ? 109.782 109.866 120.721 1.00 171.21 ?  139 PHE A N   1 
ATOM 747  C CA  . PHE A 1 157 ? 110.076 109.382 122.058 1.00 171.21 ?  139 PHE A CA  1 
ATOM 748  C C   . PHE A 1 157 ? 109.034 109.870 123.047 1.00 171.21 ?  139 PHE A C   1 
ATOM 749  O O   . PHE A 1 157 ? 108.501 109.096 123.852 1.00 171.21 ?  139 PHE A O   1 
ATOM 750  C CB  . PHE A 1 157 ? 111.465 109.840 122.470 1.00 171.21 ?  139 PHE A CB  1 
ATOM 751  C CG  . PHE A 1 157 ? 111.678 109.847 123.935 1.00 171.21 ?  139 PHE A CG  1 
ATOM 752  C CD1 . PHE A 1 157 ? 111.930 108.675 124.606 1.00 171.21 ?  139 PHE A CD1 1 
ATOM 753  C CD2 . PHE A 1 157 ? 111.631 111.022 124.643 1.00 171.21 ?  139 PHE A CD2 1 
ATOM 754  C CE1 . PHE A 1 157 ? 112.130 108.678 125.955 1.00 171.21 ?  139 PHE A CE1 1 
ATOM 755  C CE2 . PHE A 1 157 ? 111.829 111.028 125.992 1.00 171.21 ?  139 PHE A CE2 1 
ATOM 756  C CZ  . PHE A 1 157 ? 112.078 109.855 126.650 1.00 171.21 ?  139 PHE A CZ  1 
ATOM 757  N N   . ALA A 1 158 ? 108.743 111.164 123.009 1.00 168.75 ?  140 ALA A N   1 
ATOM 758  C CA  . ALA A 1 158 ? 107.697 111.691 123.869 1.00 168.75 ?  140 ALA A CA  1 
ATOM 759  C C   . ALA A 1 158 ? 106.404 110.927 123.662 1.00 168.75 ?  140 ALA A C   1 
ATOM 760  O O   . ALA A 1 158 ? 105.704 110.596 124.624 1.00 168.75 ?  140 ALA A O   1 
ATOM 761  C CB  . ALA A 1 158 ? 107.492 113.177 123.594 1.00 168.75 ?  140 ALA A CB  1 
ATOM 762  N N   . ASN A 1 159 ? 106.088 110.606 122.415 1.00 180.82 ?  141 ASN A N   1 
ATOM 763  C CA  . ASN A 1 159 ? 104.827 109.941 122.139 1.00 180.82 ?  141 ASN A CA  1 
ATOM 764  C C   . ASN A 1 159 ? 104.816 108.538 122.710 1.00 180.82 ?  141 ASN A C   1 
ATOM 765  O O   . ASN A 1 159 ? 103.814 108.096 123.280 1.00 180.82 ?  141 ASN A O   1 
ATOM 766  C CB  . ASN A 1 159 ? 104.575 109.913 120.642 1.00 180.82 ?  141 ASN A CB  1 
ATOM 767  C CG  . ASN A 1 159 ? 104.299 111.275 120.092 1.00 180.82 ?  141 ASN A CG  1 
ATOM 768  O OD1 . ASN A 1 159 ? 103.476 112.013 120.627 1.00 180.82 ?  141 ASN A OD1 1 
ATOM 769  N ND2 . ASN A 1 159 ? 104.992 111.631 119.025 1.00 180.82 ?  141 ASN A ND2 1 
ATOM 770  N N   . TYR A 1 160 ? 105.906 107.803 122.531 1.00 180.91 ?  142 TYR A N   1 
ATOM 771  C CA  . TYR A 1 160 ? 105.940 106.457 123.080 1.00 180.91 ?  142 TYR A CA  1 
ATOM 772  C C   . TYR A 1 160 ? 105.882 106.478 124.586 1.00 180.91 ?  142 TYR A C   1 
ATOM 773  O O   . TYR A 1 160 ? 105.401 105.518 125.193 1.00 180.91 ?  142 TYR A O   1 
ATOM 774  C CB  . TYR A 1 160 ? 107.187 105.712 122.643 1.00 180.91 ?  142 TYR A CB  1 
ATOM 775  C CG  . TYR A 1 160 ? 106.932 104.818 121.480 1.00 180.91 ?  142 TYR A CG  1 
ATOM 776  C CD1 . TYR A 1 160 ? 107.037 103.452 121.600 1.00 180.91 ?  142 TYR A CD1 1 
ATOM 777  C CD2 . TYR A 1 160 ? 106.583 105.345 120.258 1.00 180.91 ?  142 TYR A CD2 1 
ATOM 778  C CE1 . TYR A 1 160 ? 106.803 102.636 120.531 1.00 180.91 ?  142 TYR A CE1 1 
ATOM 779  C CE2 . TYR A 1 160 ? 106.349 104.541 119.187 1.00 180.91 ?  142 TYR A CE2 1 
ATOM 780  C CZ  . TYR A 1 160 ? 106.460 103.189 119.323 1.00 180.91 ?  142 TYR A CZ  1 
ATOM 781  O OH  . TYR A 1 160 ? 106.220 102.394 118.232 1.00 180.91 ?  142 TYR A OH  1 
ATOM 782  N N   . MET A 1 161 ? 106.365 107.542 125.204 1.00 206.89 ?  143 MET A N   1 
ATOM 783  C CA  . MET A 1 161 ? 106.218 107.640 126.642 1.00 206.89 ?  143 MET A CA  1 
ATOM 784  C C   . MET A 1 161 ? 104.794 107.972 127.040 1.00 206.89 ?  143 MET A C   1 
ATOM 785  O O   . MET A 1 161 ? 104.307 107.480 128.061 1.00 206.89 ?  143 MET A O   1 
ATOM 786  C CB  . MET A 1 161 ? 107.168 108.697 127.200 1.00 206.89 ?  143 MET A CB  1 
ATOM 787  C CG  . MET A 1 161 ? 107.143 108.802 128.707 1.00 206.89 ?  143 MET A CG  1 
ATOM 788  S SD  . MET A 1 161 ? 107.064 107.215 129.561 1.00 206.89 ?  143 MET A SD  1 
ATOM 789  C CE  . MET A 1 161 ? 108.489 106.362 128.886 1.00 206.89 ?  143 MET A CE  1 
ATOM 790  N N   . VAL A 1 162 ? 104.113 108.784 126.245 1.00 195.02 ?  144 VAL A N   1 
ATOM 791  C CA  . VAL A 1 162 ? 102.776 109.221 126.612 1.00 195.02 ?  144 VAL A CA  1 
ATOM 792  C C   . VAL A 1 162 ? 101.767 108.103 126.410 1.00 195.02 ?  144 VAL A C   1 
ATOM 793  O O   . VAL A 1 162 ? 100.997 107.764 127.315 1.00 195.02 ?  144 VAL A O   1 
ATOM 794  C CB  . VAL A 1 162 ? 102.393 110.465 125.798 1.00 195.02 ?  144 VAL A CB  1 
ATOM 795  C CG1 . VAL A 1 162 ? 100.921 110.701 125.902 1.00 195.02 ?  144 VAL A CG1 1 
ATOM 796  C CG2 . VAL A 1 162 ? 103.154 111.670 126.289 1.00 195.02 ?  144 VAL A CG2 1 
ATOM 797  N N   . GLN A 1 163 ? 101.779 107.505 125.238 1.00 191.35 ?  145 GLN A N   1 
ATOM 798  C CA  . GLN A 1 163 ? 100.696 106.682 124.722 1.00 191.35 ?  145 GLN A CA  1 
ATOM 799  C C   . GLN A 1 163 ? 100.183 105.575 125.637 1.00 191.35 ?  145 GLN A C   1 
ATOM 800  O O   . GLN A 1 163 ? 98.986  105.276 125.592 1.00 191.35 ?  145 GLN A O   1 
ATOM 801  C CB  . GLN A 1 163 ? 101.119 106.064 123.396 1.00 191.35 ?  145 GLN A CB  1 
ATOM 802  C CG  . GLN A 1 163 ? 99.944  105.638 122.579 1.00 191.35 ?  145 GLN A CG  1 
ATOM 803  C CD  . GLN A 1 163 ? 98.876  106.702 122.551 1.00 191.35 ?  145 GLN A CD  1 
ATOM 804  O OE1 . GLN A 1 163 ? 97.869  106.605 123.250 1.00 191.35 ?  145 GLN A OE1 1 
ATOM 805  N NE2 . GLN A 1 163 ? 99.090  107.731 121.747 1.00 191.35 ?  145 GLN A NE2 1 
ATOM 806  N N   . PRO A 1 164 ? 101.024 104.911 126.435 1.00 187.49 ?  146 PRO A N   1 
ATOM 807  C CA  . PRO A 1 164 ? 100.506 103.855 127.313 1.00 187.49 ?  146 PRO A CA  1 
ATOM 808  C C   . PRO A 1 164 ? 99.291  104.264 128.119 1.00 187.49 ?  146 PRO A C   1 
ATOM 809  O O   . PRO A 1 164 ? 98.339  103.491 128.234 1.00 187.49 ?  146 PRO A O   1 
ATOM 810  C CB  . PRO A 1 164 ? 101.695 103.555 128.220 1.00 187.49 ?  146 PRO A CB  1 
ATOM 811  C CG  . PRO A 1 164 ? 102.842 103.745 127.330 1.00 187.49 ?  146 PRO A CG  1 
ATOM 812  C CD  . PRO A 1 164 ? 102.494 104.879 126.400 1.00 187.49 ?  146 PRO A CD  1 
ATOM 813  N N   . LEU A 1 165 ? 99.298  105.460 128.685 1.00 181.44 ?  147 LEU A N   1 
ATOM 814  C CA  . LEU A 1 165 ? 98.078  105.977 129.277 1.00 181.44 ?  147 LEU A CA  1 
ATOM 815  C C   . LEU A 1 165 ? 97.325  106.745 128.205 1.00 181.44 ?  147 LEU A C   1 
ATOM 816  O O   . LEU A 1 165 ? 97.905  107.107 127.179 1.00 181.44 ?  147 LEU A O   1 
ATOM 817  C CB  . LEU A 1 165 ? 98.384  106.854 130.482 1.00 181.44 ?  147 LEU A CB  1 
ATOM 818  C CG  . LEU A 1 165 ? 97.193  106.980 131.428 1.00 181.44 ?  147 LEU A CG  1 
ATOM 819  C CD1 . LEU A 1 165 ? 97.655  106.859 132.856 1.00 181.44 ?  147 LEU A CD1 1 
ATOM 820  C CD2 . LEU A 1 165 ? 96.487  108.295 131.231 1.00 181.44 ?  147 LEU A CD2 1 
ATOM 821  N N   . PHE A 1 166 ? 96.044  106.983 128.439 1.00 185.75 ?  148 PHE A N   1 
ATOM 822  C CA  . PHE A 1 166 ? 95.107  107.435 127.422 1.00 185.75 ?  148 PHE A CA  1 
ATOM 823  C C   . PHE A 1 166 ? 94.984  106.376 126.342 1.00 185.75 ?  148 PHE A C   1 
ATOM 824  O O   . PHE A 1 166 ? 95.280  106.642 125.173 1.00 185.75 ?  148 PHE A O   1 
ATOM 825  C CB  . PHE A 1 166 ? 95.551  108.752 126.801 1.00 185.75 ?  148 PHE A CB  1 
ATOM 826  C CG  . PHE A 1 166 ? 95.581  109.870 127.759 1.00 185.75 ?  148 PHE A CG  1 
ATOM 827  C CD1 . PHE A 1 166 ? 94.689  109.912 128.806 1.00 185.75 ?  148 PHE A CD1 1 
ATOM 828  C CD2 . PHE A 1 166 ? 96.506  110.874 127.630 1.00 185.75 ?  148 PHE A CD2 1 
ATOM 829  C CE1 . PHE A 1 166 ? 94.713  110.947 129.703 1.00 185.75 ?  148 PHE A CE1 1 
ATOM 830  C CE2 . PHE A 1 166 ? 96.537  111.908 128.518 1.00 185.75 ?  148 PHE A CE2 1 
ATOM 831  C CZ  . PHE A 1 166 ? 95.640  111.948 129.559 1.00 185.75 ?  148 PHE A CZ  1 
ATOM 832  N N   . PRO A 1 167 ? 94.563  105.180 126.683 1.00 207.63 ?  149 PRO A N   1 
ATOM 833  C CA  . PRO A 1 167 ? 94.432  104.140 125.664 1.00 207.63 ?  149 PRO A CA  1 
ATOM 834  C C   . PRO A 1 167 ? 93.205  104.404 124.824 1.00 207.63 ?  149 PRO A C   1 
ATOM 835  O O   . PRO A 1 167 ? 92.151  104.718 125.379 1.00 207.63 ?  149 PRO A O   1 
ATOM 836  C CB  . PRO A 1 167 ? 94.285  102.854 126.486 1.00 207.63 ?  149 PRO A CB  1 
ATOM 837  C CG  . PRO A 1 167 ? 94.501  103.270 127.930 1.00 207.63 ?  149 PRO A CG  1 
ATOM 838  C CD  . PRO A 1 167 ? 94.098  104.696 127.986 1.00 207.63 ?  149 PRO A CD  1 
ATOM 839  N N   . SER A 1 168 ? 93.342  104.325 123.501 1.00 227.65 ?  150 SER A N   1 
ATOM 840  C CA  . SER A 1 168 ? 92.229  104.497 122.571 1.00 227.65 ?  150 SER A CA  1 
ATOM 841  C C   . SER A 1 168 ? 91.742  105.937 122.554 1.00 227.65 ?  150 SER A C   1 
ATOM 842  O O   . SER A 1 168 ? 90.808  106.276 121.820 1.00 227.65 ?  150 SER A O   1 
ATOM 843  C CB  . SER A 1 168 ? 91.066  103.569 122.924 1.00 227.65 ?  150 SER A CB  1 
ATOM 844  O OG  . SER A 1 168 ? 90.348  104.096 124.028 1.00 227.65 ?  150 SER A OG  1 
ATOM 845  N N   . CYS A 1 169 ? 92.350  106.783 123.371 1.00 222.08 ?  151 CYS A N   1 
ATOM 846  C CA  . CYS A 1 169 ? 91.936  108.171 123.429 1.00 222.08 ?  151 CYS A CA  1 
ATOM 847  C C   . CYS A 1 169 ? 93.156  109.045 123.218 1.00 222.08 ?  151 CYS A C   1 
ATOM 848  O O   . CYS A 1 169 ? 94.197  108.813 123.842 1.00 222.08 ?  151 CYS A O   1 
ATOM 849  C CB  . CYS A 1 169 ? 91.290  108.451 124.775 1.00 222.08 ?  151 CYS A CB  1 
ATOM 850  S SG  . CYS A 1 169 ? 90.372  107.037 125.374 1.00 222.08 ?  151 CYS A SG  1 
ATOM 851  N N   . PHE A 1 170 ? 93.054  110.031 122.338 1.00 224.71 ?  152 PHE A N   1 
ATOM 852  C CA  . PHE A 1 170 ? 94.203  110.869 122.056 1.00 224.71 ?  152 PHE A CA  1 
ATOM 853  C C   . PHE A 1 170 ? 94.650  111.615 123.314 1.00 224.71 ?  152 PHE A C   1 
ATOM 854  O O   . PHE A 1 170 ? 93.887  111.820 124.262 1.00 224.71 ?  152 PHE A O   1 
ATOM 855  C CB  . PHE A 1 170 ? 93.879  111.849 120.937 1.00 224.71 ?  152 PHE A CB  1 
ATOM 856  C CG  . PHE A 1 170 ? 92.504  112.410 121.020 1.00 224.71 ?  152 PHE A CG  1 
ATOM 857  C CD1 . PHE A 1 170 ? 91.511  111.970 120.171 1.00 224.71 ?  152 PHE A CD1 1 
ATOM 858  C CD2 . PHE A 1 170 ? 92.194  113.361 121.971 1.00 224.71 ?  152 PHE A CD2 1 
ATOM 859  C CE1 . PHE A 1 170 ? 90.240  112.487 120.254 1.00 224.71 ?  152 PHE A CE1 1 
ATOM 860  C CE2 . PHE A 1 170 ? 90.926  113.878 122.059 1.00 224.71 ?  152 PHE A CE2 1 
ATOM 861  C CZ  . PHE A 1 170 ? 89.949  113.443 121.200 1.00 224.71 ?  152 PHE A CZ  1 
ATOM 862  N N   . ALA A 1 171 ? 95.915  112.019 123.308 1.00 199.92 ?  153 ALA A N   1 
ATOM 863  C CA  . ALA A 1 171 ? 96.565  112.663 124.438 1.00 199.92 ?  153 ALA A CA  1 
ATOM 864  C C   . ALA A 1 171 ? 96.819  114.130 124.127 1.00 199.92 ?  153 ALA A C   1 
ATOM 865  O O   . ALA A 1 171 ? 96.851  114.517 122.955 1.00 199.92 ?  153 ALA A O   1 
ATOM 866  C CB  . ALA A 1 171 ? 97.873  111.951 124.758 1.00 199.92 ?  153 ALA A CB  1 
ATOM 867  N N   . PRO A 1 172 ? 97.011  114.975 125.140 1.00 190.80 ?  154 PRO A N   1 
ATOM 868  C CA  . PRO A 1 172 ? 97.162  116.417 124.895 1.00 190.80 ?  154 PRO A CA  1 
ATOM 869  C C   . PRO A 1 172 ? 98.443  116.755 124.144 1.00 190.80 ?  154 PRO A C   1 
ATOM 870  O O   . PRO A 1 172 ? 99.534  116.311 124.502 1.00 190.80 ?  154 PRO A O   1 
ATOM 871  C CB  . PRO A 1 172 ? 97.163  117.016 126.307 1.00 190.80 ?  154 PRO A CB  1 
ATOM 872  C CG  . PRO A 1 172 ? 97.438  115.872 127.216 1.00 190.80 ?  154 PRO A CG  1 
ATOM 873  C CD  . PRO A 1 172 ? 96.829  114.686 126.567 1.00 190.80 ?  154 PRO A CD  1 
ATOM 874  N N   . TYR A 1 173 ? 98.284  117.549 123.087 1.00 176.87 ?  155 TYR A N   1 
ATOM 875  C CA  . TYR A 1 173 ? 99.379  118.161 122.342 1.00 176.87 ?  155 TYR A CA  1 
ATOM 876  C C   . TYR A 1 173 ? 100.497 118.645 123.260 1.00 176.87 ?  155 TYR A C   1 
ATOM 877  O O   . TYR A 1 173 ? 101.654 118.196 123.173 1.00 176.87 ?  155 TYR A O   1 
ATOM 878  C CB  . TYR A 1 173 ? 98.774  119.328 121.563 1.00 176.87 ?  155 TYR A CB  1 
ATOM 879  C CG  . TYR A 1 173 ? 99.579  119.947 120.464 1.00 176.87 ?  155 TYR A CG  1 
ATOM 880  C CD1 . TYR A 1 173 ? 99.652  119.354 119.220 1.00 176.87 ?  155 TYR A CD1 1 
ATOM 881  C CD2 . TYR A 1 173 ? 100.199 121.169 120.645 1.00 176.87 ?  155 TYR A CD2 1 
ATOM 882  C CE1 . TYR A 1 173 ? 100.360 119.935 118.199 1.00 176.87 ?  155 TYR A CE1 1 
ATOM 883  C CE2 . TYR A 1 173 ? 100.909 121.760 119.633 1.00 176.87 ?  155 TYR A CE2 1 
ATOM 884  C CZ  . TYR A 1 173 ? 100.987 121.139 118.410 1.00 176.87 ?  155 TYR A CZ  1 
ATOM 885  O OH  . TYR A 1 173 ? 101.696 121.723 117.389 1.00 176.87 ?  155 TYR A OH  1 
ATOM 886  N N   . ALA A 1 174 ? 100.147 119.562 124.162 1.00 164.53 ?  156 ALA A N   1 
ATOM 887  C CA  . ALA A 1 174 ? 101.142 120.242 124.976 1.00 164.53 ?  156 ALA A CA  1 
ATOM 888  C C   . ALA A 1 174 ? 102.001 119.264 125.753 1.00 164.53 ?  156 ALA A C   1 
ATOM 889  O O   . ALA A 1 174 ? 103.207 119.482 125.902 1.00 164.53 ?  156 ALA A O   1 
ATOM 890  C CB  . ALA A 1 174 ? 100.453 121.210 125.932 1.00 164.53 ?  156 ALA A CB  1 
ATOM 891  N N   . ALA A 1 175 ? 101.409 118.185 126.252 1.00 170.09 ?  157 ALA A N   1 
ATOM 892  C CA  . ALA A 1 175 ? 102.169 117.263 127.082 1.00 170.09 ?  157 ALA A CA  1 
ATOM 893  C C   . ALA A 1 175 ? 103.310 116.636 126.299 1.00 170.09 ?  157 ALA A C   1 
ATOM 894  O O   . ALA A 1 175 ? 104.466 116.654 126.741 1.00 170.09 ?  157 ALA A O   1 
ATOM 895  C CB  . ALA A 1 175 ? 101.247 116.188 127.644 1.00 170.09 ?  157 ALA A CB  1 
ATOM 896  N N   . SER A 1 176 ? 103.003 116.069 125.137 1.00 164.76 ?  158 SER A N   1 
ATOM 897  C CA  . SER A 1 176 ? 104.045 115.419 124.359 1.00 164.76 ?  158 SER A CA  1 
ATOM 898  C C   . SER A 1 176 ? 105.091 116.424 123.915 1.00 164.76 ?  158 SER A C   1 
ATOM 899  O O   . SER A 1 176 ? 106.297 116.137 123.960 1.00 164.76 ?  158 SER A O   1 
ATOM 900  C CB  . SER A 1 176 ? 103.438 114.706 123.158 1.00 164.76 ?  158 SER A CB  1 
ATOM 901  O OG  . SER A 1 176 ? 104.326 113.719 122.669 1.00 164.76 ?  158 SER A OG  1 
ATOM 902  N N   . ARG A 1 177 ? 104.655 117.612 123.493 1.00 168.68 ?  159 ARG A N   1 
ATOM 903  C CA  . ARG A 1 177 ? 105.628 118.649 123.175 1.00 168.68 ?  159 ARG A CA  1 
ATOM 904  C C   . ARG A 1 177 ? 106.602 118.850 124.330 1.00 168.68 ?  159 ARG A C   1 
ATOM 905  O O   . ARG A 1 177 ? 107.825 118.737 124.168 1.00 168.68 ?  159 ARG A O   1 
ATOM 906  C CB  . ARG A 1 177 ? 104.924 119.963 122.840 1.00 168.68 ?  159 ARG A CB  1 
ATOM 907  C CG  . ARG A 1 177 ? 104.654 120.185 121.364 1.00 168.68 ?  159 ARG A CG  1 
ATOM 908  C CD  . ARG A 1 177 ? 104.115 121.598 121.105 1.00 168.68 ?  159 ARG A CD  1 
ATOM 909  N NE  . ARG A 1 177 ? 105.024 122.649 121.568 1.00 168.68 ?  159 ARG A NE  1 
ATOM 910  C CZ  . ARG A 1 177 ? 104.681 123.639 122.389 1.00 168.68 ?  159 ARG A CZ  1 
ATOM 911  N NH1 . ARG A 1 177 ? 103.439 123.739 122.836 1.00 168.68 1  159 ARG A NH1 1 
ATOM 912  N NH2 . ARG A 1 177 ? 105.582 124.540 122.752 1.00 168.68 ?  159 ARG A NH2 1 
ATOM 913  N N   . LEU A 1 178 ? 106.066 119.129 125.515 1.00 152.64 ?  160 LEU A N   1 
ATOM 914  C CA  . LEU A 1 178 ? 106.925 119.501 126.627 1.00 152.64 ?  160 LEU A CA  1 
ATOM 915  C C   . LEU A 1 178 ? 107.860 118.368 127.005 1.00 152.64 ?  160 LEU A C   1 
ATOM 916  O O   . LEU A 1 178 ? 109.026 118.601 127.344 1.00 152.64 ?  160 LEU A O   1 
ATOM 917  C CB  . LEU A 1 178 ? 106.079 119.923 127.818 1.00 152.64 ?  160 LEU A CB  1 
ATOM 918  C CG  . LEU A 1 178 ? 106.071 121.435 127.993 1.00 152.64 ?  160 LEU A CG  1 
ATOM 919  C CD1 . LEU A 1 178 ? 105.557 122.099 126.739 1.00 152.64 ?  160 LEU A CD1 1 
ATOM 920  C CD2 . LEU A 1 178 ? 105.225 121.818 129.179 1.00 152.64 ?  160 LEU A CD2 1 
ATOM 921  N N   . LEU A 1 179 ? 107.381 117.132 126.947 1.00 151.66 ?  161 LEU A N   1 
ATOM 922  C CA  . LEU A 1 179 ? 108.268 116.039 127.311 1.00 151.66 ?  161 LEU A CA  1 
ATOM 923  C C   . LEU A 1 179 ? 109.398 115.902 126.312 1.00 151.66 ?  161 LEU A C   1 
ATOM 924  O O   . LEU A 1 179 ? 110.552 115.673 126.698 1.00 151.66 ?  161 LEU A O   1 
ATOM 925  C CB  . LEU A 1 179 ? 107.497 114.738 127.437 1.00 151.66 ?  161 LEU A CB  1 
ATOM 926  C CG  . LEU A 1 179 ? 107.262 114.485 128.918 1.00 151.66 ?  161 LEU A CG  1 
ATOM 927  C CD1 . LEU A 1 179 ? 106.590 113.163 129.145 1.00 151.66 ?  161 LEU A CD1 1 
ATOM 928  C CD2 . LEU A 1 179 ? 108.584 114.532 129.635 1.00 151.66 ?  161 LEU A CD2 1 
ATOM 929  N N   . ALA A 1 180 ? 109.094 116.041 125.024 1.00 149.36 ?  162 ALA A N   1 
ATOM 930  C CA  . ALA A 1 180 ? 110.169 116.005 124.043 1.00 149.36 ?  162 ALA A CA  1 
ATOM 931  C C   . ALA A 1 180 ? 111.199 117.082 124.338 1.00 149.36 ?  162 ALA A C   1 
ATOM 932  O O   . ALA A 1 180 ? 112.412 116.839 124.258 1.00 149.36 ?  162 ALA A O   1 
ATOM 933  C CB  . ALA A 1 180 ? 109.607 116.169 122.637 1.00 149.36 ?  162 ALA A CB  1 
ATOM 934  N N   . ALA A 1 181 ? 110.732 118.276 124.690 1.00 153.49 ?  163 ALA A N   1 
ATOM 935  C CA  . ALA A 1 181 ? 111.662 119.363 124.964 1.00 153.49 ?  163 ALA A CA  1 
ATOM 936  C C   . ALA A 1 181 ? 112.556 119.029 126.146 1.00 153.49 ?  163 ALA A C   1 
ATOM 937  O O   . ALA A 1 181 ? 113.769 119.263 126.112 1.00 153.49 ?  163 ALA A O   1 
ATOM 938  C CB  . ALA A 1 181 ? 110.900 120.656 125.220 1.00 153.49 ?  163 ALA A CB  1 
ATOM 939  N N   . ALA A 1 182 ? 111.969 118.494 127.211 1.00 159.39 ?  164 ALA A N   1 
ATOM 940  C CA  . ALA A 1 182 ? 112.775 118.121 128.366 1.00 159.39 ?  164 ALA A CA  1 
ATOM 941  C C   . ALA A 1 182 ? 113.837 117.112 127.979 1.00 159.39 ?  164 ALA A C   1 
ATOM 942  O O   . ALA A 1 182 ? 115.014 117.261 128.337 1.00 159.39 ?  164 ALA A O   1 
ATOM 943  C CB  . ALA A 1 182 ? 111.886 117.553 129.464 1.00 159.39 ?  164 ALA A CB  1 
ATOM 944  N N   . CYS A 1 183 ? 113.436 116.083 127.236 1.00 156.65 ?  165 CYS A N   1 
ATOM 945  C CA  . CYS A 1 183 ? 114.382 115.065 126.803 1.00 156.65 ?  165 CYS A CA  1 
ATOM 946  C C   . CYS A 1 183 ? 115.560 115.683 126.072 1.00 156.65 ?  165 CYS A C   1 
ATOM 947  O O   . CYS A 1 183 ? 116.716 115.510 126.476 1.00 156.65 ?  165 CYS A O   1 
ATOM 948  C CB  . CYS A 1 183 ? 113.684 114.057 125.905 1.00 156.65 ?  165 CYS A CB  1 
ATOM 949  S SG  . CYS A 1 183 ? 114.790 112.802 125.277 1.00 156.65 ?  165 CYS A SG  1 
ATOM 950  N N   . ILE A 1 184 ? 115.286 116.411 124.993 1.00 148.17 ?  166 ILE A N   1 
ATOM 951  C CA  . ILE A 1 184 ? 116.374 116.940 124.175 1.00 148.17 ?  166 ILE A CA  1 
ATOM 952  C C   . ILE A 1 184 ? 117.260 117.874 124.983 1.00 148.17 ?  166 ILE A C   1 
ATOM 953  O O   . ILE A 1 184 ? 118.499 117.803 124.913 1.00 148.17 ?  166 ILE A O   1 
ATOM 954  C CB  . ILE A 1 184 ? 115.812 117.640 122.928 1.00 148.17 ?  166 ILE A CB  1 
ATOM 955  C CG1 . ILE A 1 184 ? 116.938 118.186 122.078 1.00 148.17 ?  166 ILE A CG1 1 
ATOM 956  C CG2 . ILE A 1 184 ? 114.885 118.760 123.288 1.00 148.17 ?  166 ILE A CG2 1 
ATOM 957  C CD1 . ILE A 1 184 ? 116.457 118.720 120.766 1.00 148.17 ?  166 ILE A CD1 1 
ATOM 958  N N   . CYS A 1 185 ? 116.649 118.775 125.746 1.00 167.86 ?  167 CYS A N   1 
ATOM 959  C CA  . CYS A 1 185 ? 117.431 119.783 126.432 1.00 167.86 ?  167 CYS A CA  1 
ATOM 960  C C   . CYS A 1 185 ? 118.343 119.144 127.456 1.00 167.86 ?  167 CYS A C   1 
ATOM 961  O O   . CYS A 1 185 ? 119.480 119.584 127.643 1.00 167.86 ?  167 CYS A O   1 
ATOM 962  C CB  . CYS A 1 185 ? 116.508 120.797 127.085 1.00 167.86 ?  167 CYS A CB  1 
ATOM 963  S SG  . CYS A 1 185 ? 117.361 121.936 128.150 1.00 167.86 ?  167 CYS A SG  1 
ATOM 964  N N   . LEU A 1 186 ? 117.879 118.092 128.120 1.00 157.82 ?  168 LEU A N   1 
ATOM 965  C CA  . LEU A 1 186 ? 118.788 117.375 128.995 1.00 157.82 ?  168 LEU A CA  1 
ATOM 966  C C   . LEU A 1 186 ? 119.888 116.702 128.202 1.00 157.82 ?  168 LEU A C   1 
ATOM 967  O O   . LEU A 1 186 ? 121.061 116.741 128.595 1.00 157.82 ?  168 LEU A O   1 
ATOM 968  C CB  . LEU A 1 186 ? 118.032 116.344 129.815 1.00 157.82 ?  168 LEU A CB  1 
ATOM 969  C CG  . LEU A 1 186 ? 118.963 115.429 130.598 1.00 157.82 ?  168 LEU A CG  1 
ATOM 970  C CD1 . LEU A 1 186 ? 118.408 115.197 131.972 1.00 157.82 ?  168 LEU A CD1 1 
ATOM 971  C CD2 . LEU A 1 186 ? 119.112 114.104 129.883 1.00 157.82 ?  168 LEU A CD2 1 
ATOM 972  N N   . LEU A 1 187 ? 119.523 116.048 127.104 1.00 142.15 ?  169 LEU A N   1 
ATOM 973  C CA  . LEU A 1 187 ? 120.482 115.196 126.422 1.00 142.15 ?  169 LEU A CA  1 
ATOM 974  C C   . LEU A 1 187 ? 121.680 115.992 125.950 1.00 142.15 ?  169 LEU A C   1 
ATOM 975  O O   . LEU A 1 187 ? 122.819 115.522 126.043 1.00 142.15 ?  169 LEU A O   1 
ATOM 976  C CB  . LEU A 1 187 ? 119.826 114.488 125.248 1.00 142.15 ?  169 LEU A CB  1 
ATOM 977  C CG  . LEU A 1 187 ? 120.747 113.446 124.636 1.00 142.15 ?  169 LEU A CG  1 
ATOM 978  C CD1 . LEU A 1 187 ? 121.296 112.572 125.725 1.00 142.15 ?  169 LEU A CD1 1 
ATOM 979  C CD2 . LEU A 1 187 ? 120.009 112.611 123.622 1.00 142.15 ?  169 LEU A CD2 1 
ATOM 980  N N   . THR A 1 188 ? 121.452 117.204 125.451 1.00 157.29 ?  170 THR A N   1 
ATOM 981  C CA  . THR A 1 188 ? 122.594 117.993 125.000 1.00 157.29 ?  170 THR A CA  1 
ATOM 982  C C   . THR A 1 188 ? 123.561 118.233 126.148 1.00 157.29 ?  170 THR A C   1 
ATOM 983  O O   . THR A 1 188 ? 124.709 117.773 126.123 1.00 157.29 ?  170 THR A O   1 
ATOM 984  C CB  . THR A 1 188 ? 122.156 119.328 124.422 1.00 157.29 ?  170 THR A CB  1 
ATOM 985  O OG1 . THR A 1 188 ? 121.799 120.201 125.493 1.00 157.29 ?  170 THR A OG1 1 
ATOM 986  C CG2 . THR A 1 188 ? 120.985 119.142 123.518 1.00 157.29 ?  170 THR A CG2 1 
ATOM 987  N N   . PHE A 1 189 ? 123.101 118.944 127.176 1.00 171.47 ?  171 PHE A N   1 
ATOM 988  C CA  . PHE A 1 189 ? 123.965 119.262 128.303 1.00 171.47 ?  171 PHE A CA  1 
ATOM 989  C C   . PHE A 1 189 ? 124.664 118.029 128.834 1.00 171.47 ?  171 PHE A C   1 
ATOM 990  O O   . PHE A 1 189 ? 125.808 118.110 129.290 1.00 171.47 ?  171 PHE A O   1 
ATOM 991  C CB  . PHE A 1 189 ? 123.159 119.919 129.415 1.00 171.47 ?  171 PHE A CB  1 
ATOM 992  C CG  . PHE A 1 189 ? 123.876 119.976 130.724 1.00 171.47 ?  171 PHE A CG  1 
ATOM 993  C CD1 . PHE A 1 189 ? 124.771 120.986 130.988 1.00 171.47 ?  171 PHE A CD1 1 
ATOM 994  C CD2 . PHE A 1 189 ? 123.648 119.028 131.694 1.00 171.47 ?  171 PHE A CD2 1 
ATOM 995  C CE1 . PHE A 1 189 ? 125.427 121.045 132.193 1.00 171.47 ?  171 PHE A CE1 1 
ATOM 996  C CE2 . PHE A 1 189 ? 124.303 119.084 132.897 1.00 171.47 ?  171 PHE A CE2 1 
ATOM 997  C CZ  . PHE A 1 189 ? 125.192 120.094 133.148 1.00 171.47 ?  171 PHE A CZ  1 
ATOM 998  N N   . ILE A 1 190 ? 124.006 116.876 128.779 1.00 173.80 ?  172 ILE A N   1 
ATOM 999  C CA  . ILE A 1 190 ? 124.712 115.644 129.093 1.00 173.80 ?  172 ILE A CA  1 
ATOM 1000 C C   . ILE A 1 190 ? 125.889 115.469 128.154 1.00 173.80 ?  172 ILE A C   1 
ATOM 1001 O O   . ILE A 1 190 ? 127.037 115.337 128.586 1.00 173.80 ?  172 ILE A O   1 
ATOM 1002 C CB  . ILE A 1 190 ? 123.761 114.444 129.033 1.00 173.80 ?  172 ILE A CB  1 
ATOM 1003 C CG1 . ILE A 1 190 ? 122.752 114.542 130.164 1.00 173.80 ?  172 ILE A CG1 1 
ATOM 1004 C CG2 . ILE A 1 190 ? 124.542 113.161 129.125 1.00 173.80 ?  172 ILE A CG2 1 
ATOM 1005 C CD1 . ILE A 1 190 ? 123.395 114.493 131.517 1.00 173.80 ?  172 ILE A CD1 1 
ATOM 1006 N N   . ASN A 1 191 ? 125.629 115.501 126.852 1.00 163.70 ?  173 ASN A N   1 
ATOM 1007 C CA  . ASN A 1 191 ? 126.730 115.282 125.925 1.00 163.70 ?  173 ASN A CA  1 
ATOM 1008 C C   . ASN A 1 191 ? 127.746 116.401 125.943 1.00 163.70 ?  173 ASN A C   1 
ATOM 1009 O O   . ASN A 1 191 ? 128.723 116.324 125.202 1.00 163.70 ?  173 ASN A O   1 
ATOM 1010 C CB  . ASN A 1 191 ? 126.217 115.078 124.507 1.00 163.70 ?  173 ASN A CB  1 
ATOM 1011 C CG  . ASN A 1 191 ? 126.241 113.628 124.099 1.00 163.70 ?  173 ASN A CG  1 
ATOM 1012 O OD1 . ASN A 1 191 ? 127.130 112.880 124.492 1.00 163.70 ?  173 ASN A OD1 1 
ATOM 1013 N ND2 . ASN A 1 191 ? 125.262 113.218 123.314 1.00 163.70 ?  173 ASN A ND2 1 
ATOM 1014 N N   . CYS A 1 192 ? 127.505 117.439 126.735 1.00 177.20 ?  174 CYS A N   1 
ATOM 1015 C CA  . CYS A 1 192 ? 128.482 118.506 126.863 1.00 177.20 ?  174 CYS A CA  1 
ATOM 1016 C C   . CYS A 1 192 ? 129.623 117.963 127.692 1.00 177.20 ?  174 CYS A C   1 
ATOM 1017 O O   . CYS A 1 192 ? 130.721 118.518 127.692 1.00 177.20 ?  174 CYS A O   1 
ATOM 1018 C CB  . CYS A 1 192 ? 127.867 119.733 127.527 1.00 177.20 ?  174 CYS A CB  1 
ATOM 1019 S SG  . CYS A 1 192 ? 128.985 121.146 127.671 1.00 177.20 ?  174 CYS A SG  1 
ATOM 1020 N N   . ALA A 1 193 ? 129.365 116.871 128.401 1.00 190.06 ?  175 ALA A N   1 
ATOM 1021 C CA  . ALA A 1 193 ? 130.399 116.252 129.218 1.00 190.06 ?  175 ALA A CA  1 
ATOM 1022 C C   . ALA A 1 193 ? 131.094 115.141 128.457 1.00 190.06 ?  175 ALA A C   1 
ATOM 1023 O O   . ALA A 1 193 ? 130.919 115.005 127.246 1.00 190.06 ?  175 ALA A O   1 
ATOM 1024 C CB  . ALA A 1 193 ? 129.800 115.711 130.506 1.00 190.06 ?  175 ALA A CB  1 
ATOM 1025 N N   . TYR A 1 194 ? 131.880 114.341 129.165 1.00 237.79 ?  176 TYR A N   1 
ATOM 1026 C CA  . TYR A 1 194 ? 132.577 113.231 128.534 1.00 237.79 ?  176 TYR A CA  1 
ATOM 1027 C C   . TYR A 1 194 ? 131.581 112.276 127.900 1.00 237.79 ?  176 TYR A C   1 
ATOM 1028 O O   . TYR A 1 194 ? 130.524 112.010 128.466 1.00 237.79 ?  176 TYR A O   1 
ATOM 1029 C CB  . TYR A 1 194 ? 133.430 112.494 129.562 1.00 237.79 ?  176 TYR A CB  1 
ATOM 1030 C CG  . TYR A 1 194 ? 133.848 113.346 130.739 1.00 237.79 ?  176 TYR A CG  1 
ATOM 1031 C CD1 . TYR A 1 194 ? 135.138 113.850 130.830 1.00 237.79 ?  176 TYR A CD1 1 
ATOM 1032 C CD2 . TYR A 1 194 ? 132.955 113.648 131.758 1.00 237.79 ?  176 TYR A CD2 1 
ATOM 1033 C CE1 . TYR A 1 194 ? 135.526 114.629 131.903 1.00 237.79 ?  176 TYR A CE1 1 
ATOM 1034 C CE2 . TYR A 1 194 ? 133.333 114.427 132.833 1.00 237.79 ?  176 TYR A CE2 1 
ATOM 1035 C CZ  . TYR A 1 194 ? 134.620 114.914 132.901 1.00 237.79 ?  176 TYR A CZ  1 
ATOM 1036 O OH  . TYR A 1 194 ? 135.001 115.689 133.971 1.00 237.79 ?  176 TYR A OH  1 
ATOM 1037 N N   . VAL A 1 195 ? 131.912 111.759 126.723 1.00 226.64 ?  177 VAL A N   1 
ATOM 1038 C CA  . VAL A 1 195 ? 130.999 110.860 126.024 1.00 226.64 ?  177 VAL A CA  1 
ATOM 1039 C C   . VAL A 1 195 ? 131.127 109.426 126.518 1.00 226.64 ?  177 VAL A C   1 
ATOM 1040 O O   . VAL A 1 195 ? 130.324 108.570 126.150 1.00 226.64 ?  177 VAL A O   1 
ATOM 1041 C CB  . VAL A 1 195 ? 131.235 110.889 124.502 1.00 226.64 ?  177 VAL A CB  1 
ATOM 1042 C CG1 . VAL A 1 195 ? 129.916 110.725 123.762 1.00 226.64 ?  177 VAL A CG1 1 
ATOM 1043 C CG2 . VAL A 1 195 ? 131.920 112.186 124.098 1.00 226.64 ?  177 VAL A CG2 1 
ATOM 1044 N N   . LYS A 1 196 ? 132.117 109.163 127.365 1.00 236.64 ?  178 LYS A N   1 
ATOM 1045 C CA  . LYS A 1 196 ? 132.329 107.809 127.863 1.00 236.64 ?  178 LYS A CA  1 
ATOM 1046 C C   . LYS A 1 196 ? 131.027 107.252 128.399 1.00 236.64 ?  178 LYS A C   1 
ATOM 1047 O O   . LYS A 1 196 ? 130.754 106.061 128.270 1.00 236.64 ?  178 LYS A O   1 
ATOM 1048 C CB  . LYS A 1 196 ? 133.393 107.793 128.957 1.00 236.64 ?  178 LYS A CB  1 
ATOM 1049 C CG  . LYS A 1 196 ? 133.541 109.110 129.696 1.00 236.64 ?  178 LYS A CG  1 
ATOM 1050 C CD  . LYS A 1 196 ? 134.997 109.535 129.759 1.00 236.64 ?  178 LYS A CD  1 
ATOM 1051 C CE  . LYS A 1 196 ? 135.478 109.643 131.196 1.00 236.64 ?  178 LYS A CE  1 
ATOM 1052 N NZ  . LYS A 1 196 ? 135.360 108.344 131.914 1.00 236.64 1  178 LYS A NZ  1 
ATOM 1053 N N   . TRP A 1 197 ? 130.221 108.107 129.012 1.00 246.29 ?  179 TRP A N   1 
ATOM 1054 C CA  . TRP A 1 197 ? 128.924 107.665 129.492 1.00 246.29 ?  179 TRP A CA  1 
ATOM 1055 C C   . TRP A 1 197 ? 128.077 107.267 128.300 1.00 246.29 ?  179 TRP A C   1 
ATOM 1056 O O   . TRP A 1 197 ? 127.599 106.136 128.223 1.00 246.29 ?  179 TRP A O   1 
ATOM 1057 C CB  . TRP A 1 197 ? 128.245 108.773 130.293 1.00 246.29 ?  179 TRP A CB  1 
ATOM 1058 C CG  . TRP A 1 197 ? 129.212 109.763 130.869 1.00 246.29 ?  179 TRP A CG  1 
ATOM 1059 C CD1 . TRP A 1 197 ? 129.163 111.120 130.752 1.00 246.29 ?  179 TRP A CD1 1 
ATOM 1060 C CD2 . TRP A 1 197 ? 130.376 109.470 131.652 1.00 246.29 ?  179 TRP A CD2 1 
ATOM 1061 N NE1 . TRP A 1 197 ? 130.224 111.692 131.411 1.00 246.29 ?  179 TRP A NE1 1 
ATOM 1062 C CE2 . TRP A 1 197 ? 130.983 110.699 131.973 1.00 246.29 ?  179 TRP A CE2 1 
ATOM 1063 C CE3 . TRP A 1 197 ? 130.963 108.288 132.113 1.00 246.29 ?  179 TRP A CE3 1 
ATOM 1064 C CZ2 . TRP A 1 197 ? 132.145 110.780 132.735 1.00 246.29 ?  179 TRP A CZ2 1 
ATOM 1065 C CZ3 . TRP A 1 197 ? 132.117 108.371 132.867 1.00 246.29 ?  179 TRP A CZ3 1 
ATOM 1066 C CH2 . TRP A 1 197 ? 132.695 109.608 133.172 1.00 246.29 ?  179 TRP A CH2 1 
ATOM 1067 N N   . GLY A 1 198 ? 127.906 108.188 127.357 1.00 242.24 ?  180 GLY A N   1 
ATOM 1068 C CA  . GLY A 1 198 ? 127.118 107.898 126.178 1.00 242.24 ?  180 GLY A CA  1 
ATOM 1069 C C   . GLY A 1 198 ? 127.552 106.621 125.501 1.00 242.24 ?  180 GLY A C   1 
ATOM 1070 O O   . GLY A 1 198 ? 126.717 105.830 125.067 1.00 242.24 ?  180 GLY A O   1 
ATOM 1071 N N   . THR A 1 199 ? 128.862 106.384 125.439 1.00 244.16 ?  181 THR A N   1 
ATOM 1072 C CA  . THR A 1 199 ? 129.364 105.175 124.796 1.00 244.16 ?  181 THR A CA  1 
ATOM 1073 C C   . THR A 1 199 ? 128.744 103.926 125.408 1.00 244.16 ?  181 THR A C   1 
ATOM 1074 O O   . THR A 1 199 ? 128.040 103.168 124.733 1.00 244.16 ?  181 THR A O   1 
ATOM 1075 C CB  . THR A 1 199 ? 130.884 105.111 124.905 1.00 244.16 ?  181 THR A CB  1 
ATOM 1076 O OG1 . THR A 1 199 ? 131.247 104.839 126.263 1.00 244.16 ?  181 THR A OG1 1 
ATOM 1077 C CG2 . THR A 1 199 ? 131.506 106.420 124.454 1.00 244.16 ?  181 THR A CG2 1 
ATOM 1078 N N   . LEU A 1 200 ? 129.000 103.697 126.695 1.00 239.78 ?  182 LEU A N   1 
ATOM 1079 C CA  . LEU A 1 200 ? 128.519 102.468 127.320 1.00 239.78 ?  182 LEU A CA  1 
ATOM 1080 C C   . LEU A 1 200 ? 126.998 102.376 127.290 1.00 239.78 ?  182 LEU A C   1 
ATOM 1081 O O   . LEU A 1 200 ? 126.428 101.300 127.025 1.00 239.78 ?  182 LEU A O   1 
ATOM 1082 C CB  . LEU A 1 200 ? 129.038 102.387 128.751 1.00 239.78 ?  182 LEU A CB  1 
ATOM 1083 C CG  . LEU A 1 200 ? 130.514 102.766 128.863 1.00 239.78 ?  182 LEU A CG  1 
ATOM 1084 C CD1 . LEU A 1 200 ? 130.957 102.833 130.311 1.00 239.78 ?  182 LEU A CD1 1 
ATOM 1085 C CD2 . LEU A 1 200 ? 131.368 101.784 128.079 1.00 239.78 ?  182 LEU A CD2 1 
ATOM 1086 N N   . VAL A 1 201 ? 126.315 103.495 127.528 1.00 247.49 ?  183 VAL A N   1 
ATOM 1087 C CA  . VAL A 1 201 ? 124.870 103.382 127.621 1.00 247.49 ?  183 VAL A CA  1 
ATOM 1088 C C   . VAL A 1 201 ? 124.273 103.111 126.249 1.00 247.49 ?  183 VAL A C   1 
ATOM 1089 O O   . VAL A 1 201 ? 123.270 102.408 126.134 1.00 247.49 ?  183 VAL A O   1 
ATOM 1090 C CB  . VAL A 1 201 ? 124.275 104.637 128.272 1.00 247.49 ?  183 VAL A CB  1 
ATOM 1091 C CG1 . VAL A 1 201 ? 124.781 104.766 129.704 1.00 247.49 ?  183 VAL A CG1 1 
ATOM 1092 C CG2 . VAL A 1 201 ? 124.583 105.867 127.449 1.00 247.49 ?  183 VAL A CG2 1 
ATOM 1093 N N   . GLN A 1 202 ? 124.887 103.617 125.184 1.00 245.66 ?  184 GLN A N   1 
ATOM 1094 C CA  . GLN A 1 202 ? 124.369 103.320 123.858 1.00 245.66 ?  184 GLN A CA  1 
ATOM 1095 C C   . GLN A 1 202 ? 124.715 101.900 123.449 1.00 245.66 ?  184 GLN A C   1 
ATOM 1096 O O   . GLN A 1 202 ? 123.949 101.259 122.710 1.00 245.66 ?  184 GLN A O   1 
ATOM 1097 C CB  . GLN A 1 202 ? 124.898 104.363 122.875 1.00 245.66 ?  184 GLN A CB  1 
ATOM 1098 C CG  . GLN A 1 202 ? 126.367 104.279 122.578 1.00 245.66 ?  184 GLN A CG  1 
ATOM 1099 C CD  . GLN A 1 202 ? 126.930 105.623 122.182 1.00 245.66 ?  184 GLN A CD  1 
ATOM 1100 O OE1 . GLN A 1 202 ? 126.225 106.630 122.200 1.00 245.66 ?  184 GLN A OE1 1 
ATOM 1101 N NE2 . GLN A 1 202 ? 128.206 105.652 121.836 1.00 245.66 ?  184 GLN A NE2 1 
ATOM 1102 N N   . ASP A 1 203 ? 125.840 101.388 123.956 1.00 245.05 ?  185 ASP A N   1 
ATOM 1103 C CA  . ASP A 1 203 ? 126.099 99.959  123.869 1.00 245.05 ?  185 ASP A CA  1 
ATOM 1104 C C   . ASP A 1 203 ? 124.908 99.169  124.382 1.00 245.05 ?  185 ASP A C   1 
ATOM 1105 O O   . ASP A 1 203 ? 124.468 98.203  123.748 1.00 245.05 ?  185 ASP A O   1 
ATOM 1106 C CB  . ASP A 1 203 ? 127.355 99.599  124.661 1.00 245.05 ?  185 ASP A CB  1 
ATOM 1107 C CG  . ASP A 1 203 ? 128.553 100.428 124.260 1.00 245.05 ?  185 ASP A CG  1 
ATOM 1108 O OD1 . ASP A 1 203 ? 128.530 101.000 123.150 1.00 245.05 ?  185 ASP A OD1 1 
ATOM 1109 O OD2 . ASP A 1 203 ? 129.513 100.520 125.053 1.00 245.05 -1 185 ASP A OD2 1 
ATOM 1110 N N   . ILE A 1 204 ? 124.355 99.574  125.523 1.00 226.90 ?  186 ILE A N   1 
ATOM 1111 C CA  . ILE A 1 204 ? 123.200 98.810  125.996 1.00 226.90 ?  186 ILE A CA  1 
ATOM 1112 C C   . ILE A 1 204 ? 121.931 99.170  125.223 1.00 226.90 ?  186 ILE A C   1 
ATOM 1113 O O   . ILE A 1 204 ? 121.024 98.336  125.082 1.00 226.90 ?  186 ILE A O   1 
ATOM 1114 C CB  . ILE A 1 204 ? 122.996 98.976  127.508 1.00 226.90 ?  186 ILE A CB  1 
ATOM 1115 C CG1 . ILE A 1 204 ? 122.251 97.761  128.044 1.00 226.90 ?  186 ILE A CG1 1 
ATOM 1116 C CG2 . ILE A 1 204 ? 122.176 100.199 127.815 1.00 226.90 ?  186 ILE A CG2 1 
ATOM 1117 C CD1 . ILE A 1 204 ? 122.882 96.450  127.652 1.00 226.90 ?  186 ILE A CD1 1 
ATOM 1118 N N   . PHE A 1 205 ? 121.839 100.396 124.713 1.00 219.95 ?  187 PHE A N   1 
ATOM 1119 C CA  . PHE A 1 205 ? 120.632 100.807 124.008 1.00 219.95 ?  187 PHE A CA  1 
ATOM 1120 C C   . PHE A 1 205 ? 120.427 99.980  122.759 1.00 219.95 ?  187 PHE A C   1 
ATOM 1121 O O   . PHE A 1 205 ? 119.290 99.678  122.380 1.00 219.95 ?  187 PHE A O   1 
ATOM 1122 C CB  . PHE A 1 205 ? 120.710 102.279 123.642 1.00 219.95 ?  187 PHE A CB  1 
ATOM 1123 C CG  . PHE A 1 205 ? 120.813 103.173 124.812 1.00 219.95 ?  187 PHE A CG  1 
ATOM 1124 C CD1 . PHE A 1 205 ? 120.377 102.757 126.047 1.00 219.95 ?  187 PHE A CD1 1 
ATOM 1125 C CD2 . PHE A 1 205 ? 121.346 104.430 124.685 1.00 219.95 ?  187 PHE A CD2 1 
ATOM 1126 C CE1 . PHE A 1 205 ? 120.482 103.577 127.128 1.00 219.95 ?  187 PHE A CE1 1 
ATOM 1127 C CE2 . PHE A 1 205 ? 121.449 105.253 125.757 1.00 219.95 ?  187 PHE A CE2 1 
ATOM 1128 C CZ  . PHE A 1 205 ? 121.014 104.830 126.982 1.00 219.95 ?  187 PHE A CZ  1 
ATOM 1129 N N   . THR A 1 206 ? 121.517 99.643  122.081 1.00 247.81 ?  188 THR A N   1 
ATOM 1130 C CA  . THR A 1 206 ? 121.401 98.765  120.925 1.00 247.81 ?  188 THR A CA  1 
ATOM 1131 C C   . THR A 1 206 ? 120.746 97.446  121.308 1.00 247.81 ?  188 THR A C   1 
ATOM 1132 O O   . THR A 1 206 ? 119.860 96.946  120.600 1.00 247.81 ?  188 THR A O   1 
ATOM 1133 C CB  . THR A 1 206 ? 122.778 98.521  120.321 1.00 247.81 ?  188 THR A CB  1 
ATOM 1134 O OG1 . THR A 1 206 ? 123.626 97.935  121.316 1.00 247.81 ?  188 THR A OG1 1 
ATOM 1135 C CG2 . THR A 1 206 ? 123.385 99.829  119.845 1.00 247.81 ?  188 THR A CG2 1 
ATOM 1136 N N   . TYR A 1 207 ? 121.182 96.863  122.423 1.00 250.28 ?  189 TYR A N   1 
ATOM 1137 C CA  . TYR A 1 207 ? 120.570 95.632  122.898 1.00 250.28 ?  189 TYR A CA  1 
ATOM 1138 C C   . TYR A 1 207 ? 119.088 95.841  123.159 1.00 250.28 ?  189 TYR A C   1 
ATOM 1139 O O   . TYR A 1 207 ? 118.257 94.985  122.828 1.00 250.28 ?  189 TYR A O   1 
ATOM 1140 C CB  . TYR A 1 207 ? 121.286 95.162  124.162 1.00 250.28 ?  189 TYR A CB  1 
ATOM 1141 C CG  . TYR A 1 207 ? 121.307 93.664  124.355 1.00 250.28 ?  189 TYR A CG  1 
ATOM 1142 C CD1 . TYR A 1 207 ? 122.381 92.904  123.910 1.00 250.28 ?  189 TYR A CD1 1 
ATOM 1143 C CD2 . TYR A 1 207 ? 120.262 93.011  124.991 1.00 250.28 ?  189 TYR A CD2 1 
ATOM 1144 C CE1 . TYR A 1 207 ? 122.410 91.536  124.091 1.00 250.28 ?  189 TYR A CE1 1 
ATOM 1145 C CE2 . TYR A 1 207 ? 120.282 91.642  125.175 1.00 250.28 ?  189 TYR A CE2 1 
ATOM 1146 C CZ  . TYR A 1 207 ? 121.358 90.910  124.724 1.00 250.28 ?  189 TYR A CZ  1 
ATOM 1147 O OH  . TYR A 1 207 ? 121.380 89.547  124.905 1.00 250.28 ?  189 TYR A OH  1 
ATOM 1148 N N   . ALA A 1 208 ? 118.742 96.980  123.753 1.00 233.91 ?  190 ALA A N   1 
ATOM 1149 C CA  . ALA A 1 208 ? 117.335 97.294  123.977 1.00 233.91 ?  190 ALA A CA  1 
ATOM 1150 C C   . ALA A 1 208 ? 116.561 97.266  122.668 1.00 233.91 ?  190 ALA A C   1 
ATOM 1151 O O   . ALA A 1 208 ? 115.494 96.642  122.565 1.00 233.91 ?  190 ALA A O   1 
ATOM 1152 C CB  . ALA A 1 208 ? 117.207 98.661  124.643 1.00 233.91 ?  190 ALA A CB  1 
ATOM 1153 N N   . LYS A 1 209 ? 117.093 97.945  121.658 1.00 215.81 ?  191 LYS A N   1 
ATOM 1154 C CA  . LYS A 1 209 ? 116.432 98.006  120.363 1.00 215.81 ?  191 LYS A CA  1 
ATOM 1155 C C   . LYS A 1 209 ? 116.197 96.614  119.813 1.00 215.81 ?  191 LYS A C   1 
ATOM 1156 O O   . LYS A 1 209 ? 115.077 96.264  119.417 1.00 215.81 ?  191 LYS A O   1 
ATOM 1157 C CB  . LYS A 1 209 ? 117.277 98.827  119.393 1.00 215.81 ?  191 LYS A CB  1 
ATOM 1158 C CG  . LYS A 1 209 ? 116.484 99.501  118.297 1.00 215.81 ?  191 LYS A CG  1 
ATOM 1159 C CD  . LYS A 1 209 ? 117.240 100.685 117.710 1.00 215.81 ?  191 LYS A CD  1 
ATOM 1160 C CE  . LYS A 1 209 ? 118.082 100.282 116.506 1.00 215.81 ?  191 LYS A CE  1 
ATOM 1161 N NZ  . LYS A 1 209 ? 118.276 101.415 115.558 1.00 215.81 1  191 LYS A NZ  1 
ATOM 1162 N N   . VAL A 1 210 ? 117.250 95.801  119.787 1.00 240.76 ?  192 VAL A N   1 
ATOM 1163 C CA  . VAL A 1 210 ? 117.116 94.512  119.130 1.00 240.76 ?  192 VAL A CA  1 
ATOM 1164 C C   . VAL A 1 210 ? 116.144 93.627  119.893 1.00 240.76 ?  192 VAL A C   1 
ATOM 1165 O O   . VAL A 1 210 ? 115.371 92.878  119.283 1.00 240.76 ?  192 VAL A O   1 
ATOM 1166 C CB  . VAL A 1 210 ? 118.491 93.846  118.949 1.00 240.76 ?  192 VAL A CB  1 
ATOM 1167 C CG1 . VAL A 1 210 ? 119.195 93.685  120.270 1.00 240.76 ?  192 VAL A CG1 1 
ATOM 1168 C CG2 . VAL A 1 210 ? 118.345 92.507  118.254 1.00 240.76 ?  192 VAL A CG2 1 
ATOM 1169 N N   . LEU A 1 211 ? 116.133 93.714  121.223 1.00 228.76 ?  193 LEU A N   1 
ATOM 1170 C CA  . LEU A 1 211 ? 115.189 92.906  121.984 1.00 228.76 ?  193 LEU A CA  1 
ATOM 1171 C C   . LEU A 1 211 ? 113.761 93.318  121.676 1.00 228.76 ?  193 LEU A C   1 
ATOM 1172 O O   . LEU A 1 211 ? 112.874 92.470  121.507 1.00 228.76 ?  193 LEU A O   1 
ATOM 1173 C CB  . LEU A 1 211 ? 115.472 93.025  123.476 1.00 228.76 ?  193 LEU A CB  1 
ATOM 1174 C CG  . LEU A 1 211 ? 114.659 92.053  124.326 1.00 228.76 ?  193 LEU A CG  1 
ATOM 1175 C CD1 . LEU A 1 211 ? 115.522 91.505  125.442 1.00 228.76 ?  193 LEU A CD1 1 
ATOM 1176 C CD2 . LEU A 1 211 ? 113.424 92.731  124.892 1.00 228.76 ?  193 LEU A CD2 1 
ATOM 1177 N N   . ALA A 1 212 ? 113.515 94.625  121.622 1.00 211.08 ?  194 ALA A N   1 
ATOM 1178 C CA  . ALA A 1 212 ? 112.195 95.091  121.227 1.00 211.08 ?  194 ALA A CA  1 
ATOM 1179 C C   . ALA A 1 212 ? 111.793 94.477  119.898 1.00 211.08 ?  194 ALA A C   1 
ATOM 1180 O O   . ALA A 1 212 ? 110.721 93.869  119.775 1.00 211.08 ?  194 ALA A O   1 
ATOM 1181 C CB  . ALA A 1 212 ? 112.184 96.614  121.144 1.00 211.08 ?  194 ALA A CB  1 
ATOM 1182 N N   . LEU A 1 213 ? 112.668 94.600  118.901 1.00 227.81 ?  195 LEU A N   1 
ATOM 1183 C CA  . LEU A 1 213 ? 112.347 94.114  117.563 1.00 227.81 ?  195 LEU A CA  1 
ATOM 1184 C C   . LEU A 1 213 ? 112.021 92.630  117.575 1.00 227.81 ?  195 LEU A C   1 
ATOM 1185 O O   . LEU A 1 213 ? 111.041 92.190  116.959 1.00 227.81 ?  195 LEU A O   1 
ATOM 1186 C CB  . LEU A 1 213 ? 113.506 94.392  116.610 1.00 227.81 ?  195 LEU A CB  1 
ATOM 1187 C CG  . LEU A 1 213 ? 113.555 95.730  115.874 1.00 227.81 ?  195 LEU A CG  1 
ATOM 1188 C CD1 . LEU A 1 213 ? 112.469 95.771  114.828 1.00 227.81 ?  195 LEU A CD1 1 
ATOM 1189 C CD2 . LEU A 1 213 ? 113.407 96.900  116.820 1.00 227.81 ?  195 LEU A CD2 1 
ATOM 1190 N N   . ILE A 1 214 ? 112.841 91.837  118.259 1.00 251.71 ?  196 ILE A N   1 
ATOM 1191 C CA  . ILE A 1 214 ? 112.650 90.396  118.186 1.00 251.71 ?  196 ILE A CA  1 
ATOM 1192 C C   . ILE A 1 214 ? 111.362 90.000  118.884 1.00 251.71 ?  196 ILE A C   1 
ATOM 1193 O O   . ILE A 1 214 ? 110.639 89.115  118.414 1.00 251.71 ?  196 ILE A O   1 
ATOM 1194 C CB  . ILE A 1 214 ? 113.858 89.647  118.768 1.00 251.71 ?  196 ILE A CB  1 
ATOM 1195 C CG1 . ILE A 1 214 ? 114.181 90.168  120.161 1.00 251.71 ?  196 ILE A CG1 1 
ATOM 1196 C CG2 . ILE A 1 214 ? 115.051 89.805  117.852 1.00 251.71 ?  196 ILE A CG2 1 
ATOM 1197 C CD1 . ILE A 1 214 ? 114.840 89.167  121.064 1.00 251.71 ?  196 ILE A CD1 1 
ATOM 1198 N N   . ALA A 1 215 ? 111.053 90.638  120.014 1.00 244.11 ?  197 ALA A N   1 
ATOM 1199 C CA  . ALA A 1 215 ? 109.780 90.361  120.665 1.00 244.11 ?  197 ALA A CA  1 
ATOM 1200 C C   . ALA A 1 215 ? 108.625 90.654  119.719 1.00 244.11 ?  197 ALA A C   1 
ATOM 1201 O O   . ALA A 1 215 ? 107.706 89.836  119.562 1.00 244.11 ?  197 ALA A O   1 
ATOM 1202 C CB  . ALA A 1 215 ? 109.656 91.181  121.946 1.00 244.11 ?  197 ALA A CB  1 
ATOM 1203 N N   . VAL A 1 216 ? 108.673 91.814  119.061 1.00 240.76 ?  198 VAL A N   1 
ATOM 1204 C CA  . VAL A 1 216 ? 107.619 92.173  118.115 1.00 240.76 ?  198 VAL A CA  1 
ATOM 1205 C C   . VAL A 1 216 ? 107.456 91.093  117.061 1.00 240.76 ?  198 VAL A C   1 
ATOM 1206 O O   . VAL A 1 216 ? 106.344 90.623  116.793 1.00 240.76 ?  198 VAL A O   1 
ATOM 1207 C CB  . VAL A 1 216 ? 107.912 93.532  117.461 1.00 240.76 ?  198 VAL A CB  1 
ATOM 1208 C CG1 . VAL A 1 216 ? 106.757 93.927  116.573 1.00 240.76 ?  198 VAL A CG1 1 
ATOM 1209 C CG2 . VAL A 1 216 ? 108.116 94.583  118.516 1.00 240.76 ?  198 VAL A CG2 1 
ATOM 1210 N N   . ILE A 1 217 ? 108.558 90.697  116.435 1.00 226.11 ?  199 ILE A N   1 
ATOM 1211 C CA  . ILE A 1 217 ? 108.456 89.785  115.305 1.00 226.11 ?  199 ILE A CA  1 
ATOM 1212 C C   . ILE A 1 217 ? 107.957 88.423  115.759 1.00 226.11 ?  199 ILE A C   1 
ATOM 1213 O O   . ILE A 1 217 ? 107.056 87.843  115.142 1.00 226.11 ?  199 ILE A O   1 
ATOM 1214 C CB  . ILE A 1 217 ? 109.799 89.682  114.572 1.00 226.11 ?  199 ILE A CB  1 
ATOM 1215 C CG1 . ILE A 1 217 ? 109.984 90.912  113.699 1.00 226.11 ?  199 ILE A CG1 1 
ATOM 1216 C CG2 . ILE A 1 217 ? 109.837 88.432  113.738 1.00 226.11 ?  199 ILE A CG2 1 
ATOM 1217 C CD1 . ILE A 1 217 ? 108.810 91.164  112.802 1.00 226.11 ?  199 ILE A CD1 1 
ATOM 1218 N N   . VAL A 1 218 ? 108.529 87.890  116.841 1.00 243.26 ?  200 VAL A N   1 
ATOM 1219 C CA  . VAL A 1 218 ? 108.126 86.561  117.285 1.00 243.26 ?  200 VAL A CA  1 
ATOM 1220 C C   . VAL A 1 218 ? 106.648 86.548  117.635 1.00 243.26 ?  200 VAL A C   1 
ATOM 1221 O O   . VAL A 1 218 ? 105.924 85.612  117.279 1.00 243.26 ?  200 VAL A O   1 
ATOM 1222 C CB  . VAL A 1 218 ? 108.993 86.076  118.463 1.00 243.26 ?  200 VAL A CB  1 
ATOM 1223 C CG1 . VAL A 1 218 ? 108.830 86.958  119.686 1.00 243.26 ?  200 VAL A CG1 1 
ATOM 1224 C CG2 . VAL A 1 218 ? 108.632 84.645  118.814 1.00 243.26 ?  200 VAL A CG2 1 
ATOM 1225 N N   . ALA A 1 219 ? 106.163 87.596  118.306 1.00 244.40 ?  201 ALA A N   1 
ATOM 1226 C CA  . ALA A 1 219 ? 104.750 87.629  118.656 1.00 244.40 ?  201 ALA A CA  1 
ATOM 1227 C C   . ALA A 1 219 ? 103.886 87.722  117.406 1.00 244.40 ?  201 ALA A C   1 
ATOM 1228 O O   . ALA A 1 219 ? 102.956 86.925  117.216 1.00 244.40 ?  201 ALA A O   1 
ATOM 1229 C CB  . ALA A 1 219 ? 104.473 88.798  119.600 1.00 244.40 ?  201 ALA A CB  1 
ATOM 1230 N N   . GLY A 1 220 ? 104.188 88.686  116.534 1.00 240.74 ?  202 GLY A N   1 
ATOM 1231 C CA  . GLY A 1 220 ? 103.370 88.889  115.355 1.00 240.74 ?  202 GLY A CA  1 
ATOM 1232 C C   . GLY A 1 220 ? 103.375 87.703  114.418 1.00 240.74 ?  202 GLY A C   1 
ATOM 1233 O O   . GLY A 1 220 ? 102.468 87.553  113.596 1.00 240.74 ?  202 GLY A O   1 
ATOM 1234 N N   . ILE A 1 221 ? 104.383 86.844  114.524 1.00 247.06 ?  203 ILE A N   1 
ATOM 1235 C CA  . ILE A 1 221 ? 104.429 85.690  113.639 1.00 247.06 ?  203 ILE A CA  1 
ATOM 1236 C C   . ILE A 1 221 ? 103.761 84.483  114.281 1.00 247.06 ?  203 ILE A C   1 
ATOM 1237 O O   . ILE A 1 221 ? 102.971 83.785  113.637 1.00 247.06 ?  203 ILE A O   1 
ATOM 1238 C CB  . ILE A 1 221 ? 105.877 85.393  113.224 1.00 247.06 ?  203 ILE A CB  1 
ATOM 1239 C CG1 . ILE A 1 221 ? 106.422 86.561  112.402 1.00 247.06 ?  203 ILE A CG1 1 
ATOM 1240 C CG2 . ILE A 1 221 ? 105.939 84.111  112.425 1.00 247.06 ?  203 ILE A CG2 1 
ATOM 1241 C CD1 . ILE A 1 221 ? 105.418 87.141  111.419 1.00 247.06 ?  203 ILE A CD1 1 
ATOM 1242 N N   . VAL A 1 222 ? 104.055 84.214  115.557 1.00 254.08 ?  204 VAL A N   1 
ATOM 1243 C CA  . VAL A 1 222 ? 103.394 83.104  116.229 1.00 254.08 ?  204 VAL A CA  1 
ATOM 1244 C C   . VAL A 1 222 ? 101.893 83.326  116.276 1.00 254.08 ?  204 VAL A C   1 
ATOM 1245 O O   . VAL A 1 222 ? 101.126 82.356  116.351 1.00 254.08 ?  204 VAL A O   1 
ATOM 1246 C CB  . VAL A 1 222 ? 103.971 82.893  117.645 1.00 254.08 ?  204 VAL A CB  1 
ATOM 1247 C CG1 . VAL A 1 222 ? 103.522 84.001  118.583 1.00 254.08 ?  204 VAL A CG1 1 
ATOM 1248 C CG2 . VAL A 1 222 ? 103.569 81.529  118.184 1.00 254.08 ?  204 VAL A CG2 1 
ATOM 1249 N N   . ARG A 1 223 ? 101.456 84.589  116.210 1.00 250.96 ?  205 ARG A N   1 
ATOM 1250 C CA  . ARG A 1 223 ? 100.039 84.895  116.064 1.00 250.96 ?  205 ARG A CA  1 
ATOM 1251 C C   . ARG A 1 223 ? 99.424  84.092  114.929 1.00 250.96 ?  205 ARG A C   1 
ATOM 1252 O O   . ARG A 1 223 ? 98.481  83.323  115.131 1.00 250.96 ?  205 ARG A O   1 
ATOM 1253 C CB  . ARG A 1 223 ? 99.850  86.391  115.813 1.00 250.96 ?  205 ARG A CB  1 
ATOM 1254 C CG  . ARG A 1 223 ? 98.424  86.769  115.461 1.00 250.96 ?  205 ARG A CG  1 
ATOM 1255 C CD  . ARG A 1 223 ? 97.486  86.378  116.586 1.00 250.96 ?  205 ARG A CD  1 
ATOM 1256 N NE  . ARG A 1 223 ? 96.129  86.133  116.116 1.00 250.96 ?  205 ARG A NE  1 
ATOM 1257 C CZ  . ARG A 1 223 ? 95.227  85.431  116.793 1.00 250.96 ?  205 ARG A CZ  1 
ATOM 1258 N NH1 . ARG A 1 223 ? 95.543  84.905  117.968 1.00 250.96 1  205 ARG A NH1 1 
ATOM 1259 N NH2 . ARG A 1 223 ? 94.012  85.254  116.296 1.00 250.96 ?  205 ARG A NH2 1 
ATOM 1260 N N   . LEU A 1 224 ? 99.962  84.255  113.724 1.00 259.76 ?  206 LEU A N   1 
ATOM 1261 C CA  . LEU A 1 224 ? 99.454  83.511  112.583 1.00 259.76 ?  206 LEU A CA  1 
ATOM 1262 C C   . LEU A 1 224 ? 99.837  82.044  112.653 1.00 259.76 ?  206 LEU A C   1 
ATOM 1263 O O   . LEU A 1 224 ? 99.132  81.195  112.100 1.00 259.76 ?  206 LEU A O   1 
ATOM 1264 C CB  . LEU A 1 224 ? 99.997  84.105  111.293 1.00 259.76 ?  206 LEU A CB  1 
ATOM 1265 C CG  . LEU A 1 224 ? 99.684  85.581  111.136 1.00 259.76 ?  206 LEU A CG  1 
ATOM 1266 C CD1 . LEU A 1 224 ? 100.288 86.081  109.853 1.00 259.76 ?  206 LEU A CD1 1 
ATOM 1267 C CD2 . LEU A 1 224 ? 98.199  85.797  111.175 1.00 259.76 ?  206 LEU A CD2 1 
ATOM 1268 N N   . GLY A 1 225 ? 100.949 81.735  113.317 1.00 283.99 ?  207 GLY A N   1 
ATOM 1269 C CA  . GLY A 1 225 ? 101.429 80.364  113.327 1.00 283.99 ?  207 GLY A CA  1 
ATOM 1270 C C   . GLY A 1 225 ? 100.517 79.432  114.101 1.00 283.99 ?  207 GLY A C   1 
ATOM 1271 O O   . GLY A 1 225 ? 99.892  78.536  113.527 1.00 283.99 ?  207 GLY A O   1 
ATOM 1272 N N   . GLN A 1 226 ? 100.417 79.638  115.415 1.00 283.35 ?  208 GLN A N   1 
ATOM 1273 C CA  . GLN A 1 226 ? 99.665  78.693  116.233 1.00 283.35 ?  208 GLN A CA  1 
ATOM 1274 C C   . GLN A 1 226 ? 98.160  78.821  116.035 1.00 283.35 ?  208 GLN A C   1 
ATOM 1275 O O   . GLN A 1 226 ? 97.404  78.029  116.608 1.00 283.35 ?  208 GLN A O   1 
ATOM 1276 C CB  . GLN A 1 226 ? 100.035 78.864  117.706 1.00 283.35 ?  208 GLN A CB  1 
ATOM 1277 C CG  . GLN A 1 226 ? 101.363 78.209  118.070 1.00 283.35 ?  208 GLN A CG  1 
ATOM 1278 C CD  . GLN A 1 226 ? 101.813 78.533  119.479 1.00 283.35 ?  208 GLN A CD  1 
ATOM 1279 O OE1 . GLN A 1 226 ? 101.369 79.513  120.074 1.00 283.35 ?  208 GLN A OE1 1 
ATOM 1280 N NE2 . GLN A 1 226 ? 102.707 77.712  120.018 1.00 283.35 ?  208 GLN A NE2 1 
ATOM 1281 N N   . GLY A 1 227 ? 97.713  79.782  115.237 1.00 285.85 ?  209 GLY A N   1 
ATOM 1282 C CA  . GLY A 1 227 ? 96.299  79.910  114.936 1.00 285.85 ?  209 GLY A CA  1 
ATOM 1283 C C   . GLY A 1 227 ? 96.084  81.027  113.942 1.00 285.85 ?  209 GLY A C   1 
ATOM 1284 O O   . GLY A 1 227 ? 96.981  81.830  113.671 1.00 285.85 ?  209 GLY A O   1 
ATOM 1285 N N   . ALA A 1 228 ? 94.871  81.062  113.393 1.00 290.90 ?  210 ALA A N   1 
ATOM 1286 C CA  . ALA A 1 228 ? 94.452  82.110  112.463 1.00 290.90 ?  210 ALA A CA  1 
ATOM 1287 C C   . ALA A 1 228 ? 95.462  82.284  111.334 1.00 290.90 ?  210 ALA A C   1 
ATOM 1288 O O   . ALA A 1 228 ? 95.766  83.397  110.899 1.00 290.90 ?  210 ALA A O   1 
ATOM 1289 C CB  . ALA A 1 228 ? 94.224  83.431  113.198 1.00 290.90 ?  210 ALA A CB  1 
ATOM 1290 N N   . SER A 1 229 ? 95.995  81.160  110.866 1.00 299.34 ?  211 SER A N   1 
ATOM 1291 C CA  . SER A 1 229 ? 96.958  81.195  109.776 1.00 299.34 ?  211 SER A CA  1 
ATOM 1292 C C   . SER A 1 229 ? 96.288  81.678  108.497 1.00 299.34 ?  211 SER A C   1 
ATOM 1293 O O   . SER A 1 229 ? 95.085  81.489  108.302 1.00 299.34 ?  211 SER A O   1 
ATOM 1294 C CB  . SER A 1 229 ? 97.569  79.811  109.575 1.00 299.34 ?  211 SER A CB  1 
ATOM 1295 O OG  . SER A 1 229 ? 97.995  79.270  110.814 1.00 299.34 ?  211 SER A OG  1 
ATOM 1296 N N   . THR A 1 230 ? 97.082  82.298  107.622 1.00 304.84 ?  212 THR A N   1 
ATOM 1297 C CA  . THR A 1 230 ? 96.573  82.992  106.438 1.00 304.84 ?  212 THR A CA  1 
ATOM 1298 C C   . THR A 1 230 ? 95.395  83.881  106.834 1.00 304.84 ?  212 THR A C   1 
ATOM 1299 O O   . THR A 1 230 ? 94.301  83.813  106.270 1.00 304.84 ?  212 THR A O   1 
ATOM 1300 C CB  . THR A 1 230 ? 96.193  82.001  105.331 1.00 304.84 ?  212 THR A CB  1 
ATOM 1301 O OG1 . THR A 1 230 ? 97.249  81.049  105.163 1.00 304.84 ?  212 THR A OG1 1 
ATOM 1302 C CG2 . THR A 1 230 ? 95.994  82.721  103.997 1.00 304.84 ?  212 THR A CG2 1 
ATOM 1303 N N   . HIS A 1 231 ? 95.632  84.708  107.853 1.00 279.27 ?  213 HIS A N   1 
ATOM 1304 C CA  . HIS A 1 231 ? 94.554  85.474  108.465 1.00 279.27 ?  213 HIS A CA  1 
ATOM 1305 C C   . HIS A 1 231 ? 93.886  86.402  107.463 1.00 279.27 ?  213 HIS A C   1 
ATOM 1306 O O   . HIS A 1 231 ? 92.654  86.459  107.380 1.00 279.27 ?  213 HIS A O   1 
ATOM 1307 C CB  . HIS A 1 231 ? 95.092  86.271  109.650 1.00 279.27 ?  213 HIS A CB  1 
ATOM 1308 C CG  . HIS A 1 231 ? 94.111  87.247  110.221 1.00 279.27 ?  213 HIS A CG  1 
ATOM 1309 N ND1 . HIS A 1 231 ? 93.389  86.989  111.366 1.00 279.27 ?  213 HIS A ND1 1 
ATOM 1310 C CD2 . HIS A 1 231 ? 93.741  88.485  109.815 1.00 279.27 ?  213 HIS A CD2 1 
ATOM 1311 C CE1 . HIS A 1 231 ? 92.612  88.023  111.638 1.00 279.27 ?  213 HIS A CE1 1 
ATOM 1312 N NE2 . HIS A 1 231 ? 92.806  88.944  110.711 1.00 279.27 ?  213 HIS A NE2 1 
ATOM 1313 N N   . PHE A 1 232 ? 94.676  87.151  106.699 1.00 252.52 ?  214 PHE A N   1 
ATOM 1314 C CA  . PHE A 1 232 ? 94.106  88.241  105.922 1.00 252.52 ?  214 PHE A CA  1 
ATOM 1315 C C   . PHE A 1 232 ? 94.192  87.989  104.421 1.00 252.52 ?  214 PHE A C   1 
ATOM 1316 O O   . PHE A 1 232 ? 93.159  87.938  103.748 1.00 252.52 ?  214 PHE A O   1 
ATOM 1317 C CB  . PHE A 1 232 ? 94.805  89.550  106.288 1.00 252.52 ?  214 PHE A CB  1 
ATOM 1318 C CG  . PHE A 1 232 ? 93.892  90.724  106.286 1.00 252.52 ?  214 PHE A CG  1 
ATOM 1319 C CD1 . PHE A 1 232 ? 93.120  90.999  107.402 1.00 252.52 ?  214 PHE A CD1 1 
ATOM 1320 C CD2 . PHE A 1 232 ? 93.765  91.525  105.172 1.00 252.52 ?  214 PHE A CD2 1 
ATOM 1321 C CE1 . PHE A 1 232 ? 92.267  92.072  107.418 1.00 252.52 ?  214 PHE A CE1 1 
ATOM 1322 C CE2 . PHE A 1 232 ? 92.908  92.600  105.179 1.00 252.52 ?  214 PHE A CE2 1 
ATOM 1323 C CZ  . PHE A 1 232 ? 92.157  92.875  106.305 1.00 252.52 ?  214 PHE A CZ  1 
ATOM 1324 N N   . GLU A 1 233 ? 95.406  87.812  103.895 1.00 257.88 ?  215 GLU A N   1 
ATOM 1325 C CA  . GLU A 1 233 ? 95.662  87.522  102.478 1.00 257.88 ?  215 GLU A CA  1 
ATOM 1326 C C   . GLU A 1 233 ? 94.738  88.338  101.568 1.00 257.88 ?  215 GLU A C   1 
ATOM 1327 O O   . GLU A 1 233 ? 94.040  87.816  100.697 1.00 257.88 ?  215 GLU A O   1 
ATOM 1328 C CB  . GLU A 1 233 ? 95.546  86.013  102.214 1.00 257.88 ?  215 GLU A CB  1 
ATOM 1329 C CG  . GLU A 1 233 ? 95.843  85.537  100.782 1.00 257.88 ?  215 GLU A CG  1 
ATOM 1330 C CD  . GLU A 1 233 ? 97.210  85.949  100.274 1.00 257.88 ?  215 GLU A CD  1 
ATOM 1331 O OE1 . GLU A 1 233 ? 98.126  86.156  101.095 1.00 257.88 ?  215 GLU A OE1 1 
ATOM 1332 O OE2 . GLU A 1 233 ? 97.370  86.061  99.042  1.00 257.88 -1 215 GLU A OE2 1 
ATOM 1333 N N   . ASN A 1 234 ? 94.716  89.646  101.813 1.00 257.14 ?  216 ASN A N   1 
ATOM 1334 C CA  . ASN A 1 234 ? 93.858  90.519  101.025 1.00 257.14 ?  216 ASN A CA  1 
ATOM 1335 C C   . ASN A 1 234 ? 94.289  91.973  101.138 1.00 257.14 ?  216 ASN A C   1 
ATOM 1336 O O   . ASN A 1 234 ? 94.043  92.604  102.169 1.00 257.14 ?  216 ASN A O   1 
ATOM 1337 C CB  . ASN A 1 234 ? 92.408  90.357  101.497 1.00 257.14 ?  216 ASN A CB  1 
ATOM 1338 C CG  . ASN A 1 234 ? 91.423  91.233  100.739 1.00 257.14 ?  216 ASN A CG  1 
ATOM 1339 O OD1 . ASN A 1 234 ? 91.726  92.356  100.335 1.00 257.14 ?  216 ASN A OD1 1 
ATOM 1340 N ND2 . ASN A 1 234 ? 90.220  90.711  100.546 1.00 257.14 ?  216 ASN A ND2 1 
ATOM 1341 N N   . SER A 1 235 ? 94.853  92.526  100.075 1.00 259.18 ?  217 SER A N   1 
ATOM 1342 C CA  . SER A 1 235 ? 95.170  93.945  100.088 1.00 259.18 ?  217 SER A CA  1 
ATOM 1343 C C   . SER A 1 235 ? 94.293  94.600  99.049  1.00 259.18 ?  217 SER A C   1 
ATOM 1344 O O   . SER A 1 235 ? 93.141  94.929  99.329  1.00 259.18 ?  217 SER A O   1 
ATOM 1345 C CB  . SER A 1 235 ? 96.632  94.198  99.766  1.00 259.18 ?  217 SER A CB  1 
ATOM 1346 O OG  . SER A 1 235 ? 96.798  95.528  99.309  1.00 259.18 ?  217 SER A OG  1 
ATOM 1347 N N   . PHE A 1 236 ? 94.826  94.731  97.842  1.00 272.98 ?  218 PHE A N   1 
ATOM 1348 C CA  . PHE A 1 236 ? 94.024  95.216  96.719  1.00 272.98 ?  218 PHE A CA  1 
ATOM 1349 C C   . PHE A 1 236 ? 93.527  96.650  96.748  1.00 272.98 ?  218 PHE A C   1 
ATOM 1350 O O   . PHE A 1 236 ? 93.051  97.146  95.733  1.00 272.98 ?  218 PHE A O   1 
ATOM 1351 C CB  . PHE A 1 236 ? 92.818  94.286  96.546  1.00 272.98 ?  218 PHE A CB  1 
ATOM 1352 C CG  . PHE A 1 236 ? 93.135  92.837  96.774  1.00 272.98 ?  218 PHE A CG  1 
ATOM 1353 C CD1 . PHE A 1 236 ? 94.262  92.264  96.211  1.00 272.98 ?  218 PHE A CD1 1 
ATOM 1354 C CD2 . PHE A 1 236 ? 92.307  92.050  97.552  1.00 272.98 ?  218 PHE A CD2 1 
ATOM 1355 C CE1 . PHE A 1 236 ? 94.557  90.931  96.421  1.00 272.98 ?  218 PHE A CE1 1 
ATOM 1356 C CE2 . PHE A 1 236 ? 92.595  90.717  97.766  1.00 272.98 ?  218 PHE A CE2 1 
ATOM 1357 C CZ  . PHE A 1 236 ? 93.722  90.156  97.200  1.00 272.98 ?  218 PHE A CZ  1 
ATOM 1358 N N   . GLU A 1 237 ? 93.633  97.332  97.872  1.00 254.96 ?  219 GLU A N   1 
ATOM 1359 C CA  . GLU A 1 237 ? 93.230  98.727  97.865  1.00 254.96 ?  219 GLU A CA  1 
ATOM 1360 C C   . GLU A 1 237 ? 94.056  99.447  96.819  1.00 254.96 ?  219 GLU A C   1 
ATOM 1361 O O   . GLU A 1 237 ? 95.081  98.934  96.376  1.00 254.96 ?  219 GLU A O   1 
ATOM 1362 C CB  . GLU A 1 237 ? 93.430  99.364  99.230  1.00 254.96 ?  219 GLU A CB  1 
ATOM 1363 C CG  . GLU A 1 237 ? 92.684  100.672 99.424  1.00 254.96 ?  219 GLU A CG  1 
ATOM 1364 C CD  . GLU A 1 237 ? 93.391  101.842 98.772  1.00 254.96 ?  219 GLU A CD  1 
ATOM 1365 O OE1 . GLU A 1 237 ? 94.637  101.878 98.806  1.00 254.96 ?  219 GLU A OE1 1 
ATOM 1366 O OE2 . GLU A 1 237 ? 92.702  102.708 98.197  1.00 254.96 -1 219 GLU A OE2 1 
ATOM 1367 N N   . GLY A 1 238 ? 93.612  100.624 96.400  1.00 278.71 ?  220 GLY A N   1 
ATOM 1368 C CA  . GLY A 1 238 ? 94.316  101.340 95.355  1.00 278.71 ?  220 GLY A CA  1 
ATOM 1369 C C   . GLY A 1 238 ? 95.020  102.621 95.735  1.00 278.71 ?  220 GLY A C   1 
ATOM 1370 O O   . GLY A 1 238 ? 96.047  102.574 96.407  1.00 278.71 ?  220 GLY A O   1 
ATOM 1371 N N   . SER A 1 239 ? 94.486  103.759 95.300  1.00 276.62 ?  221 SER A N   1 
ATOM 1372 C CA  . SER A 1 239 ? 95.109  105.062 95.564  1.00 276.62 ?  221 SER A CA  1 
ATOM 1373 C C   . SER A 1 239 ? 96.382  105.228 94.762  1.00 276.62 ?  221 SER A C   1 
ATOM 1374 O O   . SER A 1 239 ? 97.253  106.011 95.121  1.00 276.62 ?  221 SER A O   1 
ATOM 1375 C CB  . SER A 1 239 ? 95.399  105.255 97.049  1.00 276.62 ?  221 SER A CB  1 
ATOM 1376 O OG  . SER A 1 239 ? 96.096  106.466 97.278  1.00 276.62 ?  221 SER A OG  1 
ATOM 1377 N N   . SER A 1 240 ? 96.511  104.458 93.687  1.00 270.93 ?  222 SER A N   1 
ATOM 1378 C CA  . SER A 1 240 ? 97.723  104.513 92.878  1.00 270.93 ?  222 SER A CA  1 
ATOM 1379 C C   . SER A 1 240 ? 97.486  105.291 91.597  1.00 270.93 ?  222 SER A C   1 
ATOM 1380 O O   . SER A 1 240 ? 96.762  104.834 90.713  1.00 270.93 ?  222 SER A O   1 
ATOM 1381 C CB  . SER A 1 240 ? 98.211  103.102 92.550  1.00 270.93 ?  222 SER A CB  1 
ATOM 1382 O OG  . SER A 1 240 ? 99.251  103.136 91.588  1.00 270.93 ?  222 SER A OG  1 
ATOM 1383 N N   . PHE A 1 241 ? 98.093  106.466 91.494  1.00 274.83 ?  223 PHE A N   1 
ATOM 1384 C CA  . PHE A 1 241 ? 97.912  107.295 90.311  1.00 274.83 ?  223 PHE A CA  1 
ATOM 1385 C C   . PHE A 1 241 ? 99.235  107.518 89.601  1.00 274.83 ?  223 PHE A C   1 
ATOM 1386 O O   . PHE A 1 241 ? 99.330  108.376 88.723  1.00 274.83 ?  223 PHE A O   1 
ATOM 1387 C CB  . PHE A 1 241 ? 97.291  108.633 90.706  1.00 274.83 ?  223 PHE A CB  1 
ATOM 1388 C CG  . PHE A 1 241 ? 96.614  108.609 92.046  1.00 274.83 ?  223 PHE A CG  1 
ATOM 1389 C CD1 . PHE A 1 241 ? 95.397  107.969 92.209  1.00 274.83 ?  223 PHE A CD1 1 
ATOM 1390 C CD2 . PHE A 1 241 ? 97.197  109.216 93.145  1.00 274.83 ?  223 PHE A CD2 1 
ATOM 1391 C CE1 . PHE A 1 241 ? 94.771  107.940 93.440  1.00 274.83 ?  223 PHE A CE1 1 
ATOM 1392 C CE2 . PHE A 1 241 ? 96.576  109.191 94.379  1.00 274.83 ?  223 PHE A CE2 1 
ATOM 1393 C CZ  . PHE A 1 241 ? 95.362  108.553 94.527  1.00 274.83 ?  223 PHE A CZ  1 
ATOM 1394 N N   . ALA A 1 242 ? 100.261 106.765 89.991  1.00 252.91 ?  224 ALA A N   1 
ATOM 1395 C CA  . ALA A 1 242 ? 101.586 106.919 89.391  1.00 252.91 ?  224 ALA A CA  1 
ATOM 1396 C C   . ALA A 1 242 ? 102.126 108.306 89.684  1.00 252.91 ?  224 ALA A C   1 
ATOM 1397 O O   . ALA A 1 242 ? 103.165 108.698 89.154  1.00 252.91 ?  224 ALA A O   1 
ATOM 1398 C CB  . ALA A 1 242 ? 101.540 106.658 87.893  1.00 252.91 ?  224 ALA A CB  1 
ATOM 1399 N N   . VAL A 1 243 ? 101.424 109.051 90.530  1.00 233.60 ?  225 VAL A N   1 
ATOM 1400 C CA  . VAL A 1 243 ? 101.850 110.396 90.881  1.00 233.60 ?  225 VAL A CA  1 
ATOM 1401 C C   . VAL A 1 243 ? 101.099 110.829 92.128  1.00 233.60 ?  225 VAL A C   1 
ATOM 1402 O O   . VAL A 1 243 ? 100.002 110.339 92.396  1.00 233.60 ?  225 VAL A O   1 
ATOM 1403 C CB  . VAL A 1 243 ? 101.588 111.392 89.739  1.00 233.60 ?  225 VAL A CB  1 
ATOM 1404 C CG1 . VAL A 1 243 ? 100.096 111.644 89.583  1.00 233.60 ?  225 VAL A CG1 1 
ATOM 1405 C CG2 . VAL A 1 243 ? 102.339 112.693 89.978  1.00 233.60 ?  225 VAL A CG2 1 
ATOM 1406 N N   . GLY A 1 244 ? 101.686 111.734 92.901  1.00 228.98 ?  226 GLY A N   1 
ATOM 1407 C CA  . GLY A 1 244 ? 101.020 112.225 94.091  1.00 228.98 ?  226 GLY A CA  1 
ATOM 1408 C C   . GLY A 1 244 ? 101.474 111.563 95.372  1.00 228.98 ?  226 GLY A C   1 
ATOM 1409 O O   . GLY A 1 244 ? 102.672 111.486 95.645  1.00 228.98 ?  226 GLY A O   1 
ATOM 1410 N N   . ASP A 1 245 ? 100.523 111.083 96.164  1.00 235.48 ?  227 ASP A N   1 
ATOM 1411 C CA  . ASP A 1 245 ? 100.861 110.473 97.443  1.00 235.48 ?  227 ASP A CA  1 
ATOM 1412 C C   . ASP A 1 245 ? 101.908 109.374 97.319  1.00 235.48 ?  227 ASP A C   1 
ATOM 1413 O O   . ASP A 1 245 ? 102.555 109.019 98.308  1.00 235.48 ?  227 ASP A O   1 
ATOM 1414 C CB  . ASP A 1 245 ? 99.591  109.917 98.075  1.00 235.48 ?  227 ASP A CB  1 
ATOM 1415 C CG  . ASP A 1 245 ? 98.751  109.156 97.082  1.00 235.48 ?  227 ASP A CG  1 
ATOM 1416 O OD1 . ASP A 1 245 ? 99.148  109.112 95.899  1.00 235.48 ?  227 ASP A OD1 1 
ATOM 1417 O OD2 . ASP A 1 245 ? 97.699  108.610 97.473  1.00 235.48 -1 227 ASP A OD2 1 
ATOM 1418 N N   . ILE A 1 246 ? 102.049 108.803 96.124  1.00 226.25 ?  228 ILE A N   1 
ATOM 1419 C CA  . ILE A 1 246 ? 103.112 107.834 95.868  1.00 226.25 ?  228 ILE A CA  1 
ATOM 1420 C C   . ILE A 1 246 ? 104.471 108.388 96.292  1.00 226.25 ?  228 ILE A C   1 
ATOM 1421 O O   . ILE A 1 246 ? 105.233 107.735 97.021  1.00 226.25 ?  228 ILE A O   1 
ATOM 1422 C CB  . ILE A 1 246 ? 103.088 107.420 94.385  1.00 226.25 ?  228 ILE A CB  1 
ATOM 1423 C CG1 . ILE A 1 246 ? 104.199 106.418 94.082  1.00 226.25 ?  228 ILE A CG1 1 
ATOM 1424 C CG2 . ILE A 1 246 ? 103.091 108.644 93.469  1.00 226.25 ?  228 ILE A CG2 1 
ATOM 1425 C CD1 . ILE A 1 246 ? 104.047 105.745 92.743  1.00 226.25 ?  228 ILE A CD1 1 
ATOM 1426 N N   . ALA A 1 247 ? 104.791 109.604 95.848  1.00 215.90 ?  229 ALA A N   1 
ATOM 1427 C CA  . ALA A 1 247 ? 106.067 110.214 96.200  1.00 215.90 ?  229 ALA A CA  1 
ATOM 1428 C C   . ALA A 1 247 ? 106.251 110.263 97.706  1.00 215.90 ?  229 ALA A C   1 
ATOM 1429 O O   . ALA A 1 247 ? 107.277 109.826 98.240  1.00 215.90 ?  229 ALA A O   1 
ATOM 1430 C CB  . ALA A 1 247 ? 106.144 111.621 95.616  1.00 215.90 ?  229 ALA A CB  1 
ATOM 1431 N N   . LEU A 1 248 ? 105.260 110.791 98.410  1.00 211.03 ?  230 LEU A N   1 
ATOM 1432 C CA  . LEU A 1 248 ? 105.403 110.980 99.843  1.00 211.03 ?  230 LEU A CA  1 
ATOM 1433 C C   . LEU A 1 248 ? 105.499 109.644 100.562 1.00 211.03 ?  230 LEU A C   1 
ATOM 1434 O O   . LEU A 1 248 ? 106.205 109.524 101.574 1.00 211.03 ?  230 LEU A O   1 
ATOM 1435 C CB  . LEU A 1 248 ? 104.228 111.802 100.356 1.00 211.03 ?  230 LEU A CB  1 
ATOM 1436 C CG  . LEU A 1 248 ? 103.731 112.834 99.341  1.00 211.03 ?  230 LEU A CG  1 
ATOM 1437 C CD1 . LEU A 1 248 ? 102.514 113.548 99.880  1.00 211.03 ?  230 LEU A CD1 1 
ATOM 1438 C CD2 . LEU A 1 248 ? 104.816 113.832 98.984  1.00 211.03 ?  230 LEU A CD2 1 
ATOM 1439 N N   . ALA A 1 249 ? 104.800 108.634 100.055 1.00 210.38 ?  231 ALA A N   1 
ATOM 1440 C CA  . ALA A 1 249 ? 104.975 107.298 100.591 1.00 210.38 ?  231 ALA A CA  1 
ATOM 1441 C C   . ALA A 1 249 ? 106.421 106.869 100.469 1.00 210.38 ?  231 ALA A C   1 
ATOM 1442 O O   . ALA A 1 249 ? 106.997 106.311 101.411 1.00 210.38 ?  231 ALA A O   1 
ATOM 1443 C CB  . ALA A 1 249 ? 104.062 106.321 99.863  1.00 210.38 ?  231 ALA A CB  1 
ATOM 1444 N N   . LEU A 1 250 ? 107.034 107.145 99.321  1.00 206.58 ?  232 LEU A N   1 
ATOM 1445 C CA  . LEU A 1 250 ? 108.442 106.801 99.169  1.00 206.58 ?  232 LEU A CA  1 
ATOM 1446 C C   . LEU A 1 250 ? 109.302 107.560 100.163 1.00 206.58 ?  232 LEU A C   1 
ATOM 1447 O O   . LEU A 1 250 ? 110.268 107.013 100.703 1.00 206.58 ?  232 LEU A O   1 
ATOM 1448 C CB  . LEU A 1 250 ? 108.913 107.070 97.748  1.00 206.58 ?  232 LEU A CB  1 
ATOM 1449 C CG  . LEU A 1 250 ? 108.778 105.858 96.837  1.00 206.58 ?  232 LEU A CG  1 
ATOM 1450 C CD1 . LEU A 1 250 ? 109.626 104.728 97.381  1.00 206.58 ?  232 LEU A CD1 1 
ATOM 1451 C CD2 . LEU A 1 250 ? 107.343 105.431 96.719  1.00 206.58 ?  232 LEU A CD2 1 
ATOM 1452 N N   . TYR A 1 251 ? 108.983 108.831 100.392 1.00 194.24 ?  233 TYR A N   1 
ATOM 1453 C CA  . TYR A 1 251 ? 109.700 109.609 101.395 1.00 194.24 ?  233 TYR A CA  1 
ATOM 1454 C C   . TYR A 1 251 ? 109.710 108.886 102.727 1.00 194.24 ?  233 TYR A C   1 
ATOM 1455 O O   . TYR A 1 251 ? 110.767 108.555 103.281 1.00 194.24 ?  233 TYR A O   1 
ATOM 1456 C CB  . TYR A 1 251 ? 109.046 110.970 101.582 1.00 194.24 ?  233 TYR A CB  1 
ATOM 1457 C CG  . TYR A 1 251 ? 109.488 112.018 100.625 1.00 194.24 ?  233 TYR A CG  1 
ATOM 1458 C CD1 . TYR A 1 251 ? 110.612 111.843 99.852  1.00 194.24 ?  233 TYR A CD1 1 
ATOM 1459 C CD2 . TYR A 1 251 ? 108.796 113.206 100.519 1.00 194.24 ?  233 TYR A CD2 1 
ATOM 1460 C CE1 . TYR A 1 251 ? 111.022 112.815 98.983  1.00 194.24 ?  233 TYR A CE1 1 
ATOM 1461 C CE2 . TYR A 1 251 ? 109.200 114.182 99.661  1.00 194.24 ?  233 TYR A CE2 1 
ATOM 1462 C CZ  . TYR A 1 251 ? 110.311 113.985 98.893  1.00 194.24 ?  233 TYR A CZ  1 
ATOM 1463 O OH  . TYR A 1 251 ? 110.711 114.969 98.027  1.00 194.24 ?  233 TYR A OH  1 
ATOM 1464 N N   . SER A 1 252 ? 108.516 108.668 103.263 1.00 203.91 ?  234 SER A N   1 
ATOM 1465 C CA  . SER A 1 252 ? 108.405 108.087 104.590 1.00 203.91 ?  234 SER A CA  1 
ATOM 1466 C C   . SER A 1 252 ? 109.029 106.707 104.642 1.00 203.91 ?  234 SER A C   1 
ATOM 1467 O O   . SER A 1 252 ? 109.556 106.304 105.681 1.00 203.91 ?  234 SER A O   1 
ATOM 1468 C CB  . SER A 1 252 ? 106.945 108.034 105.013 1.00 203.91 ?  234 SER A CB  1 
ATOM 1469 O OG  . SER A 1 252 ? 106.176 107.361 104.038 1.00 203.91 ?  234 SER A OG  1 
ATOM 1470 N N   . ALA A 1 253 ? 108.970 105.978 103.532 1.00 204.31 ?  235 ALA A N   1 
ATOM 1471 C CA  . ALA A 1 253 ? 109.547 104.640 103.485 1.00 204.31 ?  235 ALA A CA  1 
ATOM 1472 C C   . ALA A 1 253 ? 111.064 104.710 103.450 1.00 204.31 ?  235 ALA A C   1 
ATOM 1473 O O   . ALA A 1 253 ? 111.738 104.132 104.303 1.00 204.31 ?  235 ALA A O   1 
ATOM 1474 C CB  . ALA A 1 253 ? 109.025 103.878 102.278 1.00 204.31 ?  235 ALA A CB  1 
ATOM 1475 N N   . LEU A 1 254 ? 111.604 105.427 102.472 1.00 207.20 ?  236 LEU A N   1 
ATOM 1476 C CA  . LEU A 1 254 ? 113.052 105.553 102.355 1.00 207.20 ?  236 LEU A CA  1 
ATOM 1477 C C   . LEU A 1 254 ? 113.622 106.192 103.608 1.00 207.20 ?  236 LEU A C   1 
ATOM 1478 O O   . LEU A 1 254 ? 114.790 105.987 103.938 1.00 207.20 ?  236 LEU A O   1 
ATOM 1479 C CB  . LEU A 1 254 ? 113.426 106.378 101.123 1.00 207.20 ?  236 LEU A CB  1 
ATOM 1480 C CG  . LEU A 1 254 ? 113.677 105.575 99.846  1.00 207.20 ?  236 LEU A CG  1 
ATOM 1481 C CD1 . LEU A 1 254 ? 112.396 104.905 99.377  1.00 207.20 ?  236 LEU A CD1 1 
ATOM 1482 C CD2 . LEU A 1 254 ? 114.258 106.451 98.747  1.00 207.20 ?  236 LEU A CD2 1 
ATOM 1483 N N   . PHE A 1 255 ? 112.801 106.964 104.311 1.00 202.93 ?  237 PHE A N   1 
ATOM 1484 C CA  . PHE A 1 255 ? 113.254 107.608 105.534 1.00 202.93 ?  237 PHE A CA  1 
ATOM 1485 C C   . PHE A 1 255 ? 113.757 106.566 106.519 1.00 202.93 ?  237 PHE A C   1 
ATOM 1486 O O   . PHE A 1 255 ? 114.798 106.752 107.146 1.00 202.93 ?  237 PHE A O   1 
ATOM 1487 C CB  . PHE A 1 255 ? 112.123 108.421 106.159 1.00 202.93 ?  237 PHE A CB  1 
ATOM 1488 C CG  . PHE A 1 255 ? 112.490 109.059 107.466 1.00 202.93 ?  237 PHE A CG  1 
ATOM 1489 C CD1 . PHE A 1 255 ? 113.284 110.192 107.499 1.00 202.93 ?  237 PHE A CD1 1 
ATOM 1490 C CD2 . PHE A 1 255 ? 112.045 108.522 108.662 1.00 202.93 ?  237 PHE A CD2 1 
ATOM 1491 C CE1 . PHE A 1 255 ? 113.625 110.781 108.701 1.00 202.93 ?  237 PHE A CE1 1 
ATOM 1492 C CE2 . PHE A 1 255 ? 112.382 109.105 109.867 1.00 202.93 ?  237 PHE A CE2 1 
ATOM 1493 C CZ  . PHE A 1 255 ? 113.174 110.237 109.887 1.00 202.93 ?  237 PHE A CZ  1 
ATOM 1494 N N   . SER A 1 256 ? 113.025 105.466 106.658 1.00 213.07 ?  238 SER A N   1 
ATOM 1495 C CA  . SER A 1 256 ? 113.466 104.394 107.541 1.00 213.07 ?  238 SER A CA  1 
ATOM 1496 C C   . SER A 1 256 ? 114.770 103.810 107.026 1.00 213.07 ?  238 SER A C   1 
ATOM 1497 O O   . SER A 1 256 ? 115.672 103.507 107.806 1.00 213.07 ?  238 SER A O   1 
ATOM 1498 C CB  . SER A 1 256 ? 112.400 103.303 107.646 1.00 213.07 ?  238 SER A CB  1 
ATOM 1499 O OG  . SER A 1 256 ? 112.438 102.674 108.916 1.00 213.07 ?  238 SER A OG  1 
ATOM 1500 N N   . TYR A 1 257 ? 114.875 103.656 105.710 1.00 220.29 ?  239 TYR A N   1 
ATOM 1501 C CA  . TYR A 1 257 ? 116.095 103.118 105.115 1.00 220.29 ?  239 TYR A CA  1 
ATOM 1502 C C   . TYR A 1 257 ? 117.263 104.084 105.255 1.00 220.29 ?  239 TYR A C   1 
ATOM 1503 O O   . TYR A 1 257 ? 118.418 103.666 105.244 1.00 220.29 ?  239 TYR A O   1 
ATOM 1504 C CB  . TYR A 1 257 ? 115.868 102.794 103.638 1.00 220.29 ?  239 TYR A CB  1 
ATOM 1505 C CG  . TYR A 1 257 ? 114.965 101.606 103.409 1.00 220.29 ?  239 TYR A CG  1 
ATOM 1506 C CD1 . TYR A 1 257 ? 115.413 100.313 103.648 1.00 220.29 ?  239 TYR A CD1 1 
ATOM 1507 C CD2 . TYR A 1 257 ? 113.665 101.775 102.954 1.00 220.29 ?  239 TYR A CD2 1 
ATOM 1508 C CE1 . TYR A 1 257 ? 114.591 99.223  103.440 1.00 220.29 ?  239 TYR A CE1 1 
ATOM 1509 C CE2 . TYR A 1 257 ? 112.837 100.691 102.741 1.00 220.29 ?  239 TYR A CE2 1 
ATOM 1510 C CZ  . TYR A 1 257 ? 113.304 99.418  102.987 1.00 220.29 ?  239 TYR A CZ  1 
ATOM 1511 O OH  . TYR A 1 257 ? 112.482 98.335  102.780 1.00 220.29 ?  239 TYR A OH  1 
ATOM 1512 N N   . SER A 1 258 ? 116.971 105.372 105.392 1.00 212.09 ?  240 SER A N   1 
ATOM 1513 C CA  . SER A 1 258 ? 118.035 106.372 105.472 1.00 212.09 ?  240 SER A CA  1 
ATOM 1514 C C   . SER A 1 258 ? 119.034 106.053 106.576 1.00 212.09 ?  240 SER A C   1 
ATOM 1515 O O   . SER A 1 258 ? 118.659 105.530 107.625 1.00 212.09 ?  240 SER A O   1 
ATOM 1516 C CB  . SER A 1 258 ? 117.442 107.766 105.690 1.00 212.09 ?  240 SER A CB  1 
ATOM 1517 O OG  . SER A 1 258 ? 117.114 107.974 107.053 1.00 212.09 ?  240 SER A OG  1 
ATOM 1518 N N   . GLY A 1 259 ? 120.306 106.365 106.343 1.00 222.05 ?  241 GLY A N   1 
ATOM 1519 C CA  . GLY A 1 259 ? 121.336 106.096 107.334 1.00 222.05 ?  241 GLY A CA  1 
ATOM 1520 C C   . GLY A 1 259 ? 122.503 105.331 106.747 1.00 222.05 ?  241 GLY A C   1 
ATOM 1521 O O   . GLY A 1 259 ? 123.551 105.205 107.382 1.00 222.05 ?  241 GLY A O   1 
ATOM 1522 N N   . TRP A 1 260 ? 122.333 104.819 105.534 1.00 229.62 ?  242 TRP A N   1 
ATOM 1523 C CA  . TRP A 1 260 ? 123.392 104.065 104.881 1.00 229.62 ?  242 TRP A CA  1 
ATOM 1524 C C   . TRP A 1 260 ? 124.273 104.966 104.055 1.00 229.62 ?  242 TRP A C   1 
ATOM 1525 O O   . TRP A 1 260 ? 125.145 104.486 103.333 1.00 229.62 ?  242 TRP A O   1 
ATOM 1526 C CB  . TRP A 1 260 ? 122.781 103.020 103.953 1.00 229.62 ?  242 TRP A CB  1 
ATOM 1527 C CG  . TRP A 1 260 ? 121.769 103.602 102.998 1.00 229.62 ?  242 TRP A CG  1 
ATOM 1528 C CD1 . TRP A 1 260 ? 120.411 103.507 103.087 1.00 229.62 ?  242 TRP A CD1 1 
ATOM 1529 C CD2 . TRP A 1 260 ? 122.037 104.377 101.820 1.00 229.62 ?  242 TRP A CD2 1 
ATOM 1530 N NE1 . TRP A 1 260 ? 119.818 104.167 102.041 1.00 229.62 ?  242 TRP A NE1 1 
ATOM 1531 C CE2 . TRP A 1 260 ? 120.793 104.709 101.248 1.00 229.62 ?  242 TRP A CE2 1 
ATOM 1532 C CE3 . TRP A 1 260 ? 123.205 104.817 101.192 1.00 229.62 ?  242 TRP A CE3 1 
ATOM 1533 C CZ2 . TRP A 1 260 ? 120.686 105.462 100.081 1.00 229.62 ?  242 TRP A CZ2 1 
ATOM 1534 C CZ3 . TRP A 1 260 ? 123.097 105.567 100.040 1.00 229.62 ?  242 TRP A CZ3 1 
ATOM 1535 C CH2 . TRP A 1 260 ? 121.847 105.880 99.494  1.00 229.62 ?  242 TRP A CH2 1 
ATOM 1536 N N   . ASP A 1 261 ? 124.068 106.273 104.146 1.00 239.72 ?  243 ASP A N   1 
ATOM 1537 C CA  . ASP A 1 261 ? 124.808 107.165 103.267 1.00 239.72 ?  243 ASP A CA  1 
ATOM 1538 C C   . ASP A 1 261 ? 126.278 107.271 103.647 1.00 239.72 ?  243 ASP A C   1 
ATOM 1539 O O   . ASP A 1 261 ? 127.154 106.883 102.872 1.00 239.72 ?  243 ASP A O   1 
ATOM 1540 C CB  . ASP A 1 261 ? 124.155 108.544 103.297 1.00 239.72 ?  243 ASP A CB  1 
ATOM 1541 C CG  . ASP A 1 261 ? 123.761 108.949 104.690 1.00 239.72 ?  243 ASP A CG  1 
ATOM 1542 O OD1 . ASP A 1 261 ? 124.027 108.161 105.623 1.00 239.72 ?  243 ASP A OD1 1 
ATOM 1543 O OD2 . ASP A 1 261 ? 123.182 110.040 104.852 1.00 239.72 -1 243 ASP A OD2 1 
ATOM 1544 N N   . THR A 1 262 ? 126.565 107.787 104.834 1.00 226.60 ?  244 THR A N   1 
ATOM 1545 C CA  . THR A 1 262 ? 127.942 108.041 105.221 1.00 226.60 ?  244 THR A CA  1 
ATOM 1546 C C   . THR A 1 262 ? 128.476 107.040 106.218 1.00 226.60 ?  244 THR A C   1 
ATOM 1547 O O   . THR A 1 262 ? 129.668 106.722 106.183 1.00 226.60 ?  244 THR A O   1 
ATOM 1548 C CB  . THR A 1 262 ? 128.080 109.444 105.816 1.00 226.60 ?  244 THR A CB  1 
ATOM 1549 O OG1 . THR A 1 262 ? 129.449 109.680 106.164 1.00 226.60 ?  244 THR A OG1 1 
ATOM 1550 C CG2 . THR A 1 262 ? 127.212 109.596 107.050 1.00 226.60 ?  244 THR A CG2 1 
ATOM 1551 N N   . LEU A 1 263 ? 127.623 106.522 107.087 1.00 228.34 ?  245 LEU A N   1 
ATOM 1552 C CA  . LEU A 1 263 ? 128.091 105.711 108.194 1.00 228.34 ?  245 LEU A CA  1 
ATOM 1553 C C   . LEU A 1 263 ? 128.760 104.424 107.745 1.00 228.34 ?  245 LEU A C   1 
ATOM 1554 O O   . LEU A 1 263 ? 129.229 103.659 108.594 1.00 228.34 ?  245 LEU A O   1 
ATOM 1555 C CB  . LEU A 1 263 ? 126.918 105.434 109.127 1.00 228.34 ?  245 LEU A CB  1 
ATOM 1556 C CG  . LEU A 1 263 ? 126.167 106.728 109.437 1.00 228.34 ?  245 LEU A CG  1 
ATOM 1557 C CD1 . LEU A 1 263 ? 124.950 106.466 110.296 1.00 228.34 ?  245 LEU A CD1 1 
ATOM 1558 C CD2 . LEU A 1 263 ? 127.098 107.714 110.117 1.00 228.34 ?  245 LEU A CD2 1 
ATOM 1559 N N   . ASN A 1 264 ? 128.835 104.177 106.440 1.00 232.38 ?  246 ASN A N   1 
ATOM 1560 C CA  . ASN A 1 264 ? 129.581 103.054 105.903 1.00 232.38 ?  246 ASN A CA  1 
ATOM 1561 C C   . ASN A 1 264 ? 130.972 103.446 105.441 1.00 232.38 ?  246 ASN A C   1 
ATOM 1562 O O   . ASN A 1 264 ? 131.904 102.643 105.560 1.00 232.38 ?  246 ASN A O   1 
ATOM 1563 C CB  . ASN A 1 264 ? 128.817 102.449 104.730 1.00 232.38 ?  246 ASN A CB  1 
ATOM 1564 C CG  . ASN A 1 264 ? 127.441 101.997 105.126 1.00 232.38 ?  246 ASN A CG  1 
ATOM 1565 O OD1 . ASN A 1 264 ? 126.448 102.586 104.714 1.00 232.38 ?  246 ASN A OD1 1 
ATOM 1566 N ND2 . ASN A 1 264 ? 127.369 100.948 105.930 1.00 232.38 ?  246 ASN A ND2 1 
ATOM 1567 N N   . TYR A 1 265 ? 131.117 104.658 104.909 1.00 231.71 ?  247 TYR A N   1 
ATOM 1568 C CA  . TYR A 1 265 ? 132.432 105.177 104.566 1.00 231.71 ?  247 TYR A CA  1 
ATOM 1569 C C   . TYR A 1 265 ? 133.366 105.111 105.763 1.00 231.71 ?  247 TYR A C   1 
ATOM 1570 O O   . TYR A 1 265 ? 134.552 104.796 105.621 1.00 231.71 ?  247 TYR A O   1 
ATOM 1571 C CB  . TYR A 1 265 ? 132.274 106.607 104.047 1.00 231.71 ?  247 TYR A CB  1 
ATOM 1572 C CG  . TYR A 1 265 ? 133.484 107.510 104.125 1.00 231.71 ?  247 TYR A CG  1 
ATOM 1573 C CD1 . TYR A 1 265 ? 133.721 108.300 105.244 1.00 231.71 ?  247 TYR A CD1 1 
ATOM 1574 C CD2 . TYR A 1 265 ? 134.361 107.616 103.056 1.00 231.71 ?  247 TYR A CD2 1 
ATOM 1575 C CE1 . TYR A 1 265 ? 134.818 109.148 105.304 1.00 231.71 ?  247 TYR A CE1 1 
ATOM 1576 C CE2 . TYR A 1 265 ? 135.457 108.460 103.104 1.00 231.71 ?  247 TYR A CE2 1 
ATOM 1577 C CZ  . TYR A 1 265 ? 135.683 109.223 104.230 1.00 231.71 ?  247 TYR A CZ  1 
ATOM 1578 O OH  . TYR A 1 265 ? 136.774 110.063 104.281 1.00 231.71 ?  247 TYR A OH  1 
ATOM 1579 N N   . VAL A 1 266 ? 132.832 105.375 106.948 1.00 225.94 ?  248 VAL A N   1 
ATOM 1580 C CA  . VAL A 1 266 ? 133.639 105.287 108.155 1.00 225.94 ?  248 VAL A CA  1 
ATOM 1581 C C   . VAL A 1 266 ? 133.757 103.841 108.611 1.00 225.94 ?  248 VAL A C   1 
ATOM 1582 O O   . VAL A 1 266 ? 134.402 103.557 109.620 1.00 225.94 ?  248 VAL A O   1 
ATOM 1583 C CB  . VAL A 1 266 ? 133.028 106.123 109.289 1.00 225.94 ?  248 VAL A CB  1 
ATOM 1584 C CG1 . VAL A 1 266 ? 132.856 107.567 108.844 1.00 225.94 ?  248 VAL A CG1 1 
ATOM 1585 C CG2 . VAL A 1 266 ? 131.691 105.533 109.711 1.00 225.94 ?  248 VAL A CG2 1 
ATOM 1586 N N   . THR A 1 267 ? 133.141 102.925 107.873 1.00 213.74 ?  249 THR A N   1 
ATOM 1587 C CA  . THR A 1 267 ? 133.161 101.515 108.258 1.00 213.74 ?  249 THR A CA  1 
ATOM 1588 C C   . THR A 1 267 ? 133.816 100.633 107.201 1.00 213.74 ?  249 THR A C   1 
ATOM 1589 O O   . THR A 1 267 ? 134.102 99.464  107.454 1.00 213.74 ?  249 THR A O   1 
ATOM 1590 C CB  . THR A 1 267 ? 131.735 100.998 108.524 1.00 213.74 ?  249 THR A CB  1 
ATOM 1591 O OG1 . THR A 1 267 ? 130.963 102.028 109.151 1.00 213.74 ?  249 THR A OG1 1 
ATOM 1592 C CG2 . THR A 1 267 ? 131.763 99.778  109.431 1.00 213.74 ?  249 THR A CG2 1 
ATOM 1593 N N   . GLU A 1 268 ? 134.064 101.188 106.020 1.00 215.91 ?  250 GLU A N   1 
ATOM 1594 C CA  . GLU A 1 268 ? 134.664 100.410 104.938 1.00 215.91 ?  250 GLU A CA  1 
ATOM 1595 C C   . GLU A 1 268 ? 136.072 99.967  105.300 1.00 215.91 ?  250 GLU A C   1 
ATOM 1596 O O   . GLU A 1 268 ? 136.641 99.093  104.646 1.00 215.91 ?  250 GLU A O   1 
ATOM 1597 C CB  . GLU A 1 268 ? 134.682 101.221 103.642 1.00 215.91 ?  250 GLU A CB  1 
ATOM 1598 C CG  . GLU A 1 268 ? 135.542 102.472 103.702 1.00 215.91 ?  250 GLU A CG  1 
ATOM 1599 C CD  . GLU A 1 268 ? 135.162 103.493 102.647 1.00 215.91 ?  250 GLU A CD  1 
ATOM 1600 O OE1 . GLU A 1 268 ? 135.409 104.697 102.866 1.00 215.91 ?  250 GLU A OE1 1 
ATOM 1601 O OE2 . GLU A 1 268 ? 134.617 103.092 101.597 1.00 215.91 -1 250 GLU A OE2 1 
ATOM 1602 N N   . GLU A 1 269 ? 136.638 100.567 106.340 1.00 218.95 ?  251 GLU A N   1 
ATOM 1603 C CA  . GLU A 1 269 ? 137.990 100.226 106.762 1.00 218.95 ?  251 GLU A CA  1 
ATOM 1604 C C   . GLU A 1 269 ? 137.974 99.144  107.827 1.00 218.95 ?  251 GLU A C   1 
ATOM 1605 O O   . GLU A 1 269 ? 139.005 98.848  108.431 1.00 218.95 ?  251 GLU A O   1 
ATOM 1606 C CB  . GLU A 1 269 ? 138.689 101.471 107.301 1.00 218.95 ?  251 GLU A CB  1 
ATOM 1607 C CG  . GLU A 1 269 ? 137.882 102.216 108.353 1.00 218.95 ?  251 GLU A CG  1 
ATOM 1608 C CD  . GLU A 1 269 ? 136.976 103.279 107.760 1.00 218.95 ?  251 GLU A CD  1 
ATOM 1609 O OE1 . GLU A 1 269 ? 136.071 102.926 106.976 1.00 218.95 ?  251 GLU A OE1 1 
ATOM 1610 O OE2 . GLU A 1 269 ? 137.166 104.471 108.081 1.00 218.95 -1 251 GLU A OE2 1 
ATOM 1611 N N   . ILE A 1 270 ? 136.810 98.554  108.068 1.00 215.76 ?  252 ILE A N   1 
ATOM 1612 C CA  . ILE A 1 270 ? 136.688 97.542  109.116 1.00 215.76 ?  252 ILE A CA  1 
ATOM 1613 C C   . ILE A 1 270 ? 137.514 96.288  108.832 1.00 215.76 ?  252 ILE A C   1 
ATOM 1614 O O   . ILE A 1 270 ? 138.225 95.803  109.711 1.00 215.76 ?  252 ILE A O   1 
ATOM 1615 C CB  . ILE A 1 270 ? 135.210 97.152  109.326 1.00 215.76 ?  252 ILE A CB  1 
ATOM 1616 C CG1 . ILE A 1 270 ? 134.624 97.927  110.508 1.00 215.76 ?  252 ILE A CG1 1 
ATOM 1617 C CG2 . ILE A 1 270 ? 135.068 95.652  109.536 1.00 215.76 ?  252 ILE A CG2 1 
ATOM 1618 C CD1 . ILE A 1 270 ? 135.191 99.321  110.673 1.00 215.76 ?  252 ILE A CD1 1 
ATOM 1619 N N   . LYS A 1 271 ? 137.431 95.769  107.612 1.00 209.31 ?  253 LYS A N   1 
ATOM 1620 C CA  . LYS A 1 271 ? 138.165 94.558  107.259 1.00 209.31 ?  253 LYS A CA  1 
ATOM 1621 C C   . LYS A 1 271 ? 138.837 94.745  105.920 1.00 209.31 ?  253 LYS A C   1 
ATOM 1622 O O   . LYS A 1 271 ? 139.847 94.105  105.631 1.00 209.31 ?  253 LYS A O   1 
ATOM 1623 C CB  . LYS A 1 271 ? 137.221 93.359  107.197 1.00 209.31 ?  253 LYS A CB  1 
ATOM 1624 C CG  . LYS A 1 271 ? 136.890 92.753  108.549 1.00 209.31 ?  253 LYS A CG  1 
ATOM 1625 C CD  . LYS A 1 271 ? 138.152 92.450  109.338 1.00 209.31 ?  253 LYS A CD  1 
ATOM 1626 C CE  . LYS A 1 271 ? 137.885 92.497  110.833 1.00 209.31 ?  253 LYS A CE  1 
ATOM 1627 N NZ  . LYS A 1 271 ? 137.148 93.730  111.223 1.00 209.31 1  253 LYS A NZ  1 
ATOM 1628 N N   . ASN A 1 272 ? 138.285 95.628  105.093 1.00 219.55 ?  254 ASN A N   1 
ATOM 1629 C CA  . ASN A 1 272 ? 138.821 95.818  103.748 1.00 219.55 ?  254 ASN A CA  1 
ATOM 1630 C C   . ASN A 1 272 ? 139.043 94.467  103.080 1.00 219.55 ?  254 ASN A C   1 
ATOM 1631 O O   . ASN A 1 272 ? 140.160 94.149  102.675 1.00 219.55 ?  254 ASN A O   1 
ATOM 1632 C CB  . ASN A 1 272 ? 140.125 96.618  103.777 1.00 219.55 ?  254 ASN A CB  1 
ATOM 1633 C CG  . ASN A 1 272 ? 140.454 97.151  105.157 1.00 219.55 ?  254 ASN A CG  1 
ATOM 1634 O OD1 . ASN A 1 272 ? 139.783 98.047  105.663 1.00 219.55 ?  254 ASN A OD1 1 
ATOM 1635 N ND2 . ASN A 1 272 ? 141.490 96.596  105.775 1.00 219.55 ?  254 ASN A ND2 1 
ATOM 1636 N N   . PRO A 1 273 ? 137.975 93.662  102.963 1.00 211.02 ?  255 PRO A N   1 
ATOM 1637 C CA  . PRO A 1 273 ? 138.126 92.327  102.384 1.00 211.02 ?  255 PRO A CA  1 
ATOM 1638 C C   . PRO A 1 273 ? 138.142 92.381  100.866 1.00 211.02 ?  255 PRO A C   1 
ATOM 1639 O O   . PRO A 1 273 ? 137.159 92.007  100.232 1.00 211.02 ?  255 PRO A O   1 
ATOM 1640 C CB  . PRO A 1 273 ? 136.871 91.603  102.869 1.00 211.02 ?  255 PRO A CB  1 
ATOM 1641 C CG  . PRO A 1 273 ? 135.846 92.682  102.974 1.00 211.02 ?  255 PRO A CG  1 
ATOM 1642 C CD  . PRO A 1 273 ? 136.577 93.948  103.334 1.00 211.02 ?  255 PRO A CD  1 
ATOM 1643 N N   . GLU A 1 274 ? 139.240 92.852  100.287 1.00 208.49 ?  256 GLU A N   1 
ATOM 1644 C CA  . GLU A 1 274 ? 139.351 92.902  98.836  1.00 208.49 ?  256 GLU A CA  1 
ATOM 1645 C C   . GLU A 1 274 ? 138.115 93.544  98.231  1.00 208.49 ?  256 GLU A C   1 
ATOM 1646 O O   . GLU A 1 274 ? 137.750 94.659  98.597  1.00 208.49 ?  256 GLU A O   1 
ATOM 1647 C CB  . GLU A 1 274 ? 139.549 91.497  98.265  1.00 208.49 ?  256 GLU A CB  1 
ATOM 1648 C CG  . GLU A 1 274 ? 140.740 91.374  97.332  1.00 208.49 ?  256 GLU A CG  1 
ATOM 1649 C CD  . GLU A 1 274 ? 140.448 91.903  95.943  1.00 208.49 ?  256 GLU A CD  1 
ATOM 1650 O OE1 . GLU A 1 274 ? 140.397 91.090  94.996  1.00 208.49 ?  256 GLU A OE1 1 
ATOM 1651 O OE2 . GLU A 1 274 ? 140.268 93.130  95.796  1.00 208.49 -1 256 GLU A OE2 1 
ATOM 1652 N N   . ARG A 1 275 ? 137.469 92.843  97.307  1.00 192.10 ?  257 ARG A N   1 
ATOM 1653 C CA  . ARG A 1 275 ? 136.263 93.368  96.679  1.00 192.10 ?  257 ARG A CA  1 
ATOM 1654 C C   . ARG A 1 275 ? 135.021 92.759  97.307  1.00 192.10 ?  257 ARG A C   1 
ATOM 1655 O O   . ARG A 1 275 ? 133.937 92.812  96.729  1.00 192.10 ?  257 ARG A O   1 
ATOM 1656 C CB  . ARG A 1 275 ? 136.277 93.092  95.177  1.00 192.10 ?  257 ARG A CB  1 
ATOM 1657 C CG  . ARG A 1 275 ? 137.351 92.111  94.740  1.00 192.10 ?  257 ARG A CG  1 
ATOM 1658 C CD  . ARG A 1 275 ? 136.782 90.718  94.527  1.00 192.10 ?  257 ARG A CD  1 
ATOM 1659 N NE  . ARG A 1 275 ? 136.270 90.135  95.763  1.00 192.10 ?  257 ARG A NE  1 
ATOM 1660 C CZ  . ARG A 1 275 ? 134.983 89.912  96.004  1.00 192.10 ?  257 ARG A CZ  1 
ATOM 1661 N NH1 . ARG A 1 275 ? 134.604 89.378  97.156  1.00 192.10 1  257 ARG A NH1 1 
ATOM 1662 N NH2 . ARG A 1 275 ? 134.072 90.230  95.095  1.00 192.10 ?  257 ARG A NH2 1 
ATOM 1663 N N   . ASN A 1 276 ? 135.177 92.163  98.483  1.00 190.72 ?  258 ASN A N   1 
ATOM 1664 C CA  . ASN A 1 276 ? 134.041 91.563  99.169  1.00 190.72 ?  258 ASN A CA  1 
ATOM 1665 C C   . ASN A 1 276 ? 133.195 92.628  99.848  1.00 190.72 ?  258 ASN A C   1 
ATOM 1666 O O   . ASN A 1 276 ? 132.077 92.356  100.278 1.00 190.72 ?  258 ASN A O   1 
ATOM 1667 C CB  . ASN A 1 276 ? 134.514 90.538  100.199 1.00 190.72 ?  258 ASN A CB  1 
ATOM 1668 C CG  . ASN A 1 276 ? 135.391 89.463  99.589  1.00 190.72 ?  258 ASN A CG  1 
ATOM 1669 O OD1 . ASN A 1 276 ? 136.298 89.752  98.809  1.00 190.72 ?  258 ASN A OD1 1 
ATOM 1670 N ND2 . ASN A 1 276 ? 135.123 88.212  99.944  1.00 190.72 ?  258 ASN A ND2 1 
ATOM 1671 N N   . LEU A 1 277 ? 133.725 93.842  99.945  1.00 197.90 ?  259 LEU A N   1 
ATOM 1672 C CA  . LEU A 1 277 ? 132.994 94.920  100.602 1.00 197.90 ?  259 LEU A CA  1 
ATOM 1673 C C   . LEU A 1 277 ? 131.642 95.173  99.935  1.00 197.90 ?  259 LEU A C   1 
ATOM 1674 O O   . LEU A 1 277 ? 130.617 95.200  100.613 1.00 197.90 ?  259 LEU A O   1 
ATOM 1675 C CB  . LEU A 1 277 ? 133.829 96.205  100.626 1.00 197.90 ?  259 LEU A CB  1 
ATOM 1676 C CG  . LEU A 1 277 ? 135.293 96.086  100.198 1.00 197.90 ?  259 LEU A CG  1 
ATOM 1677 C CD1 . LEU A 1 277 ? 135.533 96.838  98.899  1.00 197.90 ?  259 LEU A CD1 1 
ATOM 1678 C CD2 . LEU A 1 277 ? 136.212 96.609  101.290 1.00 197.90 ?  259 LEU A CD2 1 
ATOM 1679 N N   . PRO A 1 278 ? 131.626 95.345  98.601  1.00 221.02 ?  260 PRO A N   1 
ATOM 1680 C CA  . PRO A 1 278 ? 130.327 95.498  97.940  1.00 221.02 ?  260 PRO A CA  1 
ATOM 1681 C C   . PRO A 1 278 ? 129.518 94.217  98.035  1.00 221.02 ?  260 PRO A C   1 
ATOM 1682 O O   . PRO A 1 278 ? 128.302 94.273  98.208  1.00 221.02 ?  260 PRO A O   1 
ATOM 1683 C CB  . PRO A 1 278 ? 130.702 95.785  96.483  1.00 221.02 ?  260 PRO A CB  1 
ATOM 1684 C CG  . PRO A 1 278 ? 132.076 95.233  96.323  1.00 221.02 ?  260 PRO A CG  1 
ATOM 1685 C CD  . PRO A 1 278 ? 132.743 95.448  97.647  1.00 221.02 ?  260 PRO A CD  1 
ATOM 1686 N N   . LEU A 1 279 ? 130.183 93.072  97.923  1.00 218.19 ?  261 LEU A N   1 
ATOM 1687 C CA  . LEU A 1 279 ? 129.487 91.804  98.047  1.00 218.19 ?  261 LEU A CA  1 
ATOM 1688 C C   . LEU A 1 279 ? 128.800 91.765  99.392  1.00 218.19 ?  261 LEU A C   1 
ATOM 1689 O O   . LEU A 1 279 ? 127.624 91.418  99.488  1.00 218.19 ?  261 LEU A O   1 
ATOM 1690 C CB  . LEU A 1 279 ? 130.462 90.636  97.920  1.00 218.19 ?  261 LEU A CB  1 
ATOM 1691 C CG  . LEU A 1 279 ? 130.149 89.416  98.789  1.00 218.19 ?  261 LEU A CG  1 
ATOM 1692 C CD1 . LEU A 1 279 ? 129.965 88.174  97.932  1.00 218.19 ?  261 LEU A CD1 1 
ATOM 1693 C CD2 . LEU A 1 279 ? 131.229 89.198  99.837  1.00 218.19 ?  261 LEU A CD2 1 
ATOM 1694 N N   . SER A 1 280 ? 129.529 92.137  100.438 1.00 219.21 ?  262 SER A N   1 
ATOM 1695 C CA  . SER A 1 280 ? 128.945 92.171  101.767 1.00 219.21 ?  262 SER A CA  1 
ATOM 1696 C C   . SER A 1 280 ? 127.837 93.204  101.791 1.00 219.21 ?  262 SER A C   1 
ATOM 1697 O O   . SER A 1 280 ? 126.784 92.976  102.379 1.00 219.21 ?  262 SER A O   1 
ATOM 1698 C CB  . SER A 1 280 ? 130.009 92.503  102.809 1.00 219.21 ?  262 SER A CB  1 
ATOM 1699 O OG  . SER A 1 280 ? 129.419 92.996  103.996 1.00 219.21 ?  262 SER A OG  1 
ATOM 1700 N N   . ILE A 1 281 ? 128.071 94.343  101.148 1.00 220.37 ?  263 ILE A N   1 
ATOM 1701 C CA  . ILE A 1 281 ? 127.052 95.382  101.083 1.00 220.37 ?  263 ILE A CA  1 
ATOM 1702 C C   . ILE A 1 281 ? 125.789 94.816  100.455 1.00 220.37 ?  263 ILE A C   1 
ATOM 1703 O O   . ILE A 1 281 ? 124.680 95.222  100.801 1.00 220.37 ?  263 ILE A O   1 
ATOM 1704 C CB  . ILE A 1 281 ? 127.545 96.608  100.289 1.00 220.37 ?  263 ILE A CB  1 
ATOM 1705 C CG1 . ILE A 1 281 ? 127.626 97.834  101.200 1.00 220.37 ?  263 ILE A CG1 1 
ATOM 1706 C CG2 . ILE A 1 281 ? 126.638 96.891  99.101  1.00 220.37 ?  263 ILE A CG2 1 
ATOM 1707 C CD1 . ILE A 1 281 ? 127.532 99.149  100.457 1.00 220.37 ?  263 ILE A CD1 1 
ATOM 1708 N N   . GLY A 1 282 ? 125.950 93.870  99.536  1.00 231.74 ?  264 GLY A N   1 
ATOM 1709 C CA  . GLY A 1 282 ? 124.796 93.247  98.925  1.00 231.74 ?  264 GLY A CA  1 
ATOM 1710 C C   . GLY A 1 282 ? 124.269 92.077  99.708  1.00 231.74 ?  264 GLY A C   1 
ATOM 1711 O O   . GLY A 1 282 ? 123.090 91.733  99.582  1.00 231.74 ?  264 GLY A O   1 
ATOM 1712 N N   . ILE A 1 283 ? 125.119 91.441  100.503 1.00 235.65 ?  265 ILE A N   1 
ATOM 1713 C CA  . ILE A 1 283 ? 124.588 90.496  101.461 1.00 235.65 ?  265 ILE A CA  1 
ATOM 1714 C C   . ILE A 1 283 ? 123.903 91.244  102.585 1.00 235.65 ?  265 ILE A C   1 
ATOM 1715 O O   . ILE A 1 283 ? 122.943 90.743  103.179 1.00 235.65 ?  265 ILE A O   1 
ATOM 1716 C CB  . ILE A 1 283 ? 125.711 89.586  101.971 1.00 235.65 ?  265 ILE A CB  1 
ATOM 1717 C CG1 . ILE A 1 283 ? 126.339 88.844  100.794 1.00 235.65 ?  265 ILE A CG1 1 
ATOM 1718 C CG2 . ILE A 1 283 ? 125.178 88.603  102.989 1.00 235.65 ?  265 ILE A CG2 1 
ATOM 1719 C CD1 . ILE A 1 283 ? 125.329 88.192  99.877  1.00 235.65 ?  265 ILE A CD1 1 
ATOM 1720 N N   . SER A 1 284 ? 124.346 92.465  102.866 1.00 227.63 ?  266 SER A N   1 
ATOM 1721 C CA  . SER A 1 284 ? 123.803 93.201  103.998 1.00 227.63 ?  266 SER A CA  1 
ATOM 1722 C C   . SER A 1 284 ? 122.395 93.706  103.714 1.00 227.63 ?  266 SER A C   1 
ATOM 1723 O O   . SER A 1 284 ? 121.432 93.315  104.383 1.00 227.63 ?  266 SER A O   1 
ATOM 1724 C CB  . SER A 1 284 ? 124.728 94.364  104.342 1.00 227.63 ?  266 SER A CB  1 
ATOM 1725 O OG  . SER A 1 284 ? 124.768 95.290  103.275 1.00 227.63 ?  266 SER A OG  1 
ATOM 1726 N N   . MET A 1 285 ? 122.253 94.567  102.711 1.00 224.24 ?  267 MET A N   1 
ATOM 1727 C CA  . MET A 1 285 ? 121.044 95.386  102.629 1.00 224.24 ?  267 MET A CA  1 
ATOM 1728 C C   . MET A 1 285 ? 119.753 94.600  102.427 1.00 224.24 ?  267 MET A C   1 
ATOM 1729 O O   . MET A 1 285 ? 118.738 94.959  103.057 1.00 224.24 ?  267 MET A O   1 
ATOM 1730 C CB  . MET A 1 285 ? 121.210 96.431  101.530 1.00 224.24 ?  267 MET A CB  1 
ATOM 1731 C CG  . MET A 1 285 ? 120.078 97.398  101.495 1.00 224.24 ?  267 MET A CG  1 
ATOM 1732 S SD  . MET A 1 285 ? 120.715 98.990  101.014 1.00 224.24 ?  267 MET A SD  1 
ATOM 1733 C CE  . MET A 1 285 ? 121.801 99.298  102.395 1.00 224.24 ?  267 MET A CE  1 
ATOM 1734 N N   . PRO A 1 286 ? 119.698 93.580  101.575 1.00 219.24 ?  268 PRO A N   1 
ATOM 1735 C CA  . PRO A 1 286 ? 118.488 92.755  101.521 1.00 219.24 ?  268 PRO A CA  1 
ATOM 1736 C C   . PRO A 1 286 ? 118.004 92.291  102.881 1.00 219.24 ?  268 PRO A C   1 
ATOM 1737 O O   . PRO A 1 286 ? 116.790 92.258  103.103 1.00 219.24 ?  268 PRO A O   1 
ATOM 1738 C CB  . PRO A 1 286 ? 118.927 91.587  100.639 1.00 219.24 ?  268 PRO A CB  1 
ATOM 1739 C CG  . PRO A 1 286 ? 119.871 92.205  99.700  1.00 219.24 ?  268 PRO A CG  1 
ATOM 1740 C CD  . PRO A 1 286 ? 120.605 93.266  100.462 1.00 219.24 ?  268 PRO A CD  1 
ATOM 1741 N N   . ILE A 1 287 ? 118.907 91.935  103.797 1.00 226.02 ?  269 ILE A N   1 
ATOM 1742 C CA  . ILE A 1 287 ? 118.477 91.552  105.140 1.00 226.02 ?  269 ILE A CA  1 
ATOM 1743 C C   . ILE A 1 287 ? 117.693 92.681  105.787 1.00 226.02 ?  269 ILE A C   1 
ATOM 1744 O O   . ILE A 1 287 ? 116.650 92.460  106.417 1.00 226.02 ?  269 ILE A O   1 
ATOM 1745 C CB  . ILE A 1 287 ? 119.685 91.144  106.000 1.00 226.02 ?  269 ILE A CB  1 
ATOM 1746 C CG1 . ILE A 1 287 ? 119.980 89.659  105.829 1.00 226.02 ?  269 ILE A CG1 1 
ATOM 1747 C CG2 . ILE A 1 287 ? 119.444 91.472  107.458 1.00 226.02 ?  269 ILE A CG2 1 
ATOM 1748 C CD1 . ILE A 1 287 ? 121.075 89.158  106.734 1.00 226.02 ?  269 ILE A CD1 1 
ATOM 1749 N N   . VAL A 1 288 ? 118.180 93.907  105.635 1.00 218.68 ?  270 VAL A N   1 
ATOM 1750 C CA  . VAL A 1 288 ? 117.486 95.057  106.192 1.00 218.68 ?  270 VAL A CA  1 
ATOM 1751 C C   . VAL A 1 288 ? 116.081 95.154  105.619 1.00 218.68 ?  270 VAL A C   1 
ATOM 1752 O O   . VAL A 1 288 ? 115.091 95.275  106.358 1.00 218.68 ?  270 VAL A O   1 
ATOM 1753 C CB  . VAL A 1 288 ? 118.290 96.333  105.913 1.00 218.68 ?  270 VAL A CB  1 
ATOM 1754 C CG1 . VAL A 1 288 ? 117.813 97.448  106.791 1.00 218.68 ?  270 VAL A CG1 1 
ATOM 1755 C CG2 . VAL A 1 288 ? 119.760 96.063  106.117 1.00 218.68 ?  270 VAL A CG2 1 
ATOM 1756 N N   . THR A 1 289 ? 115.979 95.127  104.289 1.00 222.49 ?  271 THR A N   1 
ATOM 1757 C CA  . THR A 1 289 ? 114.668 95.251  103.661 1.00 222.49 ?  271 THR A CA  1 
ATOM 1758 C C   . THR A 1 289 ? 113.723 94.179  104.165 1.00 222.49 ?  271 THR A C   1 
ATOM 1759 O O   . THR A 1 289 ? 112.558 94.455  104.485 1.00 222.49 ?  271 THR A O   1 
ATOM 1760 C CB  . THR A 1 289 ? 114.792 95.150  102.148 1.00 222.49 ?  271 THR A CB  1 
ATOM 1761 O OG1 . THR A 1 289 ? 115.860 95.988  101.699 1.00 222.49 ?  271 THR A OG1 1 
ATOM 1762 C CG2 . THR A 1 289 ? 113.506 95.590  101.498 1.00 222.49 ?  271 THR A CG2 1 
ATOM 1763 N N   . ILE A 1 290 ? 114.214 92.948  104.243 1.00 222.68 ?  272 ILE A N   1 
ATOM 1764 C CA  . ILE A 1 290 ? 113.363 91.843  104.647 1.00 222.68 ?  272 ILE A CA  1 
ATOM 1765 C C   . ILE A 1 290 ? 112.892 92.028  106.076 1.00 222.68 ?  272 ILE A C   1 
ATOM 1766 O O   . ILE A 1 290 ? 111.726 91.774  106.392 1.00 222.68 ?  272 ILE A O   1 
ATOM 1767 C CB  . ILE A 1 290 ? 114.097 90.506  104.459 1.00 222.68 ?  272 ILE A CB  1 
ATOM 1768 C CG1 . ILE A 1 290 ? 114.473 90.314  102.992 1.00 222.68 ?  272 ILE A CG1 1 
ATOM 1769 C CG2 . ILE A 1 290 ? 113.244 89.362  104.945 1.00 222.68 ?  272 ILE A CG2 1 
ATOM 1770 C CD1 . ILE A 1 290 ? 113.357 90.636  102.030 1.00 222.68 ?  272 ILE A CD1 1 
ATOM 1771 N N   . ILE A 1 291 ? 113.776 92.472  106.963 1.00 203.62 ?  273 ILE A N   1 
ATOM 1772 C CA  . ILE A 1 291 ? 113.357 92.614  108.349 1.00 203.62 ?  273 ILE A CA  1 
ATOM 1773 C C   . ILE A 1 291 ? 112.307 93.704  108.475 1.00 203.62 ?  273 ILE A C   1 
ATOM 1774 O O   . ILE A 1 291 ? 111.309 93.544  109.193 1.00 203.62 ?  273 ILE A O   1 
ATOM 1775 C CB  . ILE A 1 291 ? 114.565 92.871  109.254 1.00 203.62 ?  273 ILE A CB  1 
ATOM 1776 C CG1 . ILE A 1 291 ? 115.459 91.642  109.252 1.00 203.62 ?  273 ILE A CG1 1 
ATOM 1777 C CG2 . ILE A 1 291 ? 114.104 93.154  110.653 1.00 203.62 ?  273 ILE A CG2 1 
ATOM 1778 C CD1 . ILE A 1 291 ? 116.752 91.847  109.963 1.00 203.62 ?  273 ILE A CD1 1 
ATOM 1779 N N   . TYR A 1 292 ? 112.495 94.816  107.765 1.00 214.28 ?  274 TYR A N   1 
ATOM 1780 C CA  . TYR A 1 292 ? 111.448 95.831  107.732 1.00 214.28 ?  274 TYR A CA  1 
ATOM 1781 C C   . TYR A 1 292 ? 110.115 95.235  107.309 1.00 214.28 ?  274 TYR A C   1 
ATOM 1782 O O   . TYR A 1 292 ? 109.109 95.354  108.021 1.00 214.28 ?  274 TYR A O   1 
ATOM 1783 C CB  . TYR A 1 292 ? 111.823 96.974  106.793 1.00 214.28 ?  274 TYR A CB  1 
ATOM 1784 C CG  . TYR A 1 292 ? 112.695 98.040  107.398 1.00 214.28 ?  274 TYR A CG  1 
ATOM 1785 C CD1 . TYR A 1 292 ? 112.983 98.049  108.749 1.00 214.28 ?  274 TYR A CD1 1 
ATOM 1786 C CD2 . TYR A 1 292 ? 113.170 99.081  106.623 1.00 214.28 ?  274 TYR A CD2 1 
ATOM 1787 C CE1 . TYR A 1 292 ? 113.761 99.047  109.304 1.00 214.28 ?  274 TYR A CE1 1 
ATOM 1788 C CE2 . TYR A 1 292 ? 113.942 100.081 107.165 1.00 214.28 ?  274 TYR A CE2 1 
ATOM 1789 C CZ  . TYR A 1 292 ? 114.237 100.062 108.504 1.00 214.28 ?  274 TYR A CZ  1 
ATOM 1790 O OH  . TYR A 1 292 ? 115.010 101.070 109.036 1.00 214.28 ?  274 TYR A OH  1 
ATOM 1791 N N   . ILE A 1 293 ? 110.089 94.602  106.137 1.00 209.71 ?  275 ILE A N   1 
ATOM 1792 C CA  . ILE A 1 293 ? 108.832 94.087  105.607 1.00 209.71 ?  275 ILE A CA  1 
ATOM 1793 C C   . ILE A 1 293 ? 108.213 93.094  106.578 1.00 209.71 ?  275 ILE A C   1 
ATOM 1794 O O   . ILE A 1 293 ? 106.988 93.040  106.745 1.00 209.71 ?  275 ILE A O   1 
ATOM 1795 C CB  . ILE A 1 293 ? 109.063 93.471  104.218 1.00 209.71 ?  275 ILE A CB  1 
ATOM 1796 C CG1 . ILE A 1 293 ? 108.999 94.558  103.151 1.00 209.71 ?  275 ILE A CG1 1 
ATOM 1797 C CG2 . ILE A 1 293 ? 108.060 92.385  103.935 1.00 209.71 ?  275 ILE A CG2 1 
ATOM 1798 C CD1 . ILE A 1 293 ? 109.365 94.074  101.779 1.00 209.71 ?  275 ILE A CD1 1 
ATOM 1799 N N   . LEU A 1 294 ? 109.052 92.311  107.249 1.00 201.81 ?  276 LEU A N   1 
ATOM 1800 C CA  . LEU A 1 294 ? 108.563 91.367  108.241 1.00 201.81 ?  276 LEU A CA  1 
ATOM 1801 C C   . LEU A 1 294 ? 107.825 92.089  109.356 1.00 201.81 ?  276 LEU A C   1 
ATOM 1802 O O   . LEU A 1 294 ? 106.717 91.699  109.751 1.00 201.81 ?  276 LEU A O   1 
ATOM 1803 C CB  . LEU A 1 294 ? 109.737 90.576  108.798 1.00 201.81 ?  276 LEU A CB  1 
ATOM 1804 C CG  . LEU A 1 294 ? 109.389 89.469  109.774 1.00 201.81 ?  276 LEU A CG  1 
ATOM 1805 C CD1 . LEU A 1 294 ? 108.558 88.433  109.073 1.00 201.81 ?  276 LEU A CD1 1 
ATOM 1806 C CD2 . LEU A 1 294 ? 110.658 88.864  110.315 1.00 201.81 ?  276 LEU A CD2 1 
ATOM 1807 N N   . THR A 1 295 ? 108.431 93.151  109.878 1.00 211.25 ?  277 THR A N   1 
ATOM 1808 C CA  . THR A 1 295 ? 107.750 93.955  110.884 1.00 211.25 ?  277 THR A CA  1 
ATOM 1809 C C   . THR A 1 295 ? 106.413 94.460  110.368 1.00 211.25 ?  277 THR A C   1 
ATOM 1810 O O   . THR A 1 295 ? 105.394 94.401  111.070 1.00 211.25 ?  277 THR A O   1 
ATOM 1811 C CB  . THR A 1 295 ? 108.625 95.129  111.285 1.00 211.25 ?  277 THR A CB  1 
ATOM 1812 O OG1 . THR A 1 295 ? 108.734 96.021  110.172 1.00 211.25 ?  277 THR A OG1 1 
ATOM 1813 C CG2 . THR A 1 295 ? 109.990 94.644  111.682 1.00 211.25 ?  277 THR A CG2 1 
ATOM 1814 N N   . ASN A 1 296 ? 106.409 94.990  109.150 1.00 215.71 ?  278 ASN A N   1 
ATOM 1815 C CA  . ASN A 1 296 ? 105.187 95.572  108.613 1.00 215.71 ?  278 ASN A CA  1 
ATOM 1816 C C   . ASN A 1 296 ? 104.073 94.541  108.568 1.00 215.71 ?  278 ASN A C   1 
ATOM 1817 O O   . ASN A 1 296 ? 102.938 94.811  108.979 1.00 215.71 ?  278 ASN A O   1 
ATOM 1818 C CB  . ASN A 1 296 ? 105.441 96.142  107.224 1.00 215.71 ?  278 ASN A CB  1 
ATOM 1819 C CG  . ASN A 1 296 ? 106.383 97.312  107.248 1.00 215.71 ?  278 ASN A CG  1 
ATOM 1820 O OD1 . ASN A 1 296 ? 105.962 98.466  107.190 1.00 215.71 ?  278 ASN A OD1 1 
ATOM 1821 N ND2 . ASN A 1 296 ? 107.672 97.025  107.326 1.00 215.71 ?  278 ASN A ND2 1 
ATOM 1822 N N   . VAL A 1 297 ? 104.382 93.347  108.070 1.00 210.51 ?  279 VAL A N   1 
ATOM 1823 C CA  . VAL A 1 297 ? 103.327 92.354  107.956 1.00 210.51 ?  279 VAL A CA  1 
ATOM 1824 C C   . VAL A 1 297 ? 102.899 91.876  109.330 1.00 210.51 ?  279 VAL A C   1 
ATOM 1825 O O   . VAL A 1 297 ? 101.739 91.506  109.522 1.00 210.51 ?  279 VAL A O   1 
ATOM 1826 C CB  . VAL A 1 297 ? 103.753 91.188  107.051 1.00 210.51 ?  279 VAL A CB  1 
ATOM 1827 C CG1 . VAL A 1 297 ? 104.283 91.719  105.734 1.00 210.51 ?  279 VAL A CG1 1 
ATOM 1828 C CG2 . VAL A 1 297 ? 104.775 90.317  107.741 1.00 210.51 ?  279 VAL A CG2 1 
ATOM 1829 N N   . ALA A 1 298 ? 103.798 91.886  110.313 1.00 204.24 ?  280 ALA A N   1 
ATOM 1830 C CA  . ALA A 1 298 ? 103.351 91.608  111.672 1.00 204.24 ?  280 ALA A CA  1 
ATOM 1831 C C   . ALA A 1 298 ? 102.291 92.617  112.095 1.00 204.24 ?  280 ALA A C   1 
ATOM 1832 O O   . ALA A 1 298 ? 101.182 92.246  112.519 1.00 204.24 ?  280 ALA A O   1 
ATOM 1833 C CB  . ALA A 1 298 ? 104.539 91.624  112.629 1.00 204.24 ?  280 ALA A CB  1 
ATOM 1834 N N   . TYR A 1 299 ? 102.614 93.906  111.948 1.00 214.15 ?  281 TYR A N   1 
ATOM 1835 C CA  . TYR A 1 299 ? 101.644 94.965  112.215 1.00 214.15 ?  281 TYR A CA  1 
ATOM 1836 C C   . TYR A 1 299 ? 100.306 94.655  111.569 1.00 214.15 ?  281 TYR A C   1 
ATOM 1837 O O   . TYR A 1 299 ? 99.269  94.612  112.239 1.00 214.15 ?  281 TYR A O   1 
ATOM 1838 C CB  . TYR A 1 299 ? 102.154 96.311  111.699 1.00 214.15 ?  281 TYR A CB  1 
ATOM 1839 C CG  . TYR A 1 299 ? 103.034 97.071  112.654 1.00 214.15 ?  281 TYR A CG  1 
ATOM 1840 C CD1 . TYR A 1 299 ? 103.186 96.658  113.960 1.00 214.15 ?  281 TYR A CD1 1 
ATOM 1841 C CD2 . TYR A 1 299 ? 103.701 98.218  112.249 1.00 214.15 ?  281 TYR A CD2 1 
ATOM 1842 C CE1 . TYR A 1 299 ? 103.987 97.354  114.837 1.00 214.15 ?  281 TYR A CE1 1 
ATOM 1843 C CE2 . TYR A 1 299 ? 104.507 98.921  113.119 1.00 214.15 ?  281 TYR A CE2 1 
ATOM 1844 C CZ  . TYR A 1 299 ? 104.645 98.483  114.412 1.00 214.15 ?  281 TYR A CZ  1 
ATOM 1845 O OH  . TYR A 1 299 ? 105.443 99.172  115.289 1.00 214.15 ?  281 TYR A OH  1 
ATOM 1846 N N   . TYR A 1 300 ? 100.319 94.419  110.260 1.00 224.95 ?  282 TYR A N   1 
ATOM 1847 C CA  . TYR A 1 300 ? 99.068  94.222  109.538 1.00 224.95 ?  282 TYR A CA  1 
ATOM 1848 C C   . TYR A 1 300 ? 98.306  93.025  110.079 1.00 224.95 ?  282 TYR A C   1 
ATOM 1849 O O   . TYR A 1 300 ? 97.161  93.155  110.524 1.00 224.95 ?  282 TYR A O   1 
ATOM 1850 C CB  . TYR A 1 300 ? 99.340  94.058  108.050 1.00 224.95 ?  282 TYR A CB  1 
ATOM 1851 C CG  . TYR A 1 300 ? 99.842  95.321  107.416 1.00 224.95 ?  282 TYR A CG  1 
ATOM 1852 C CD1 . TYR A 1 300 ? 99.132  96.502  107.529 1.00 224.95 ?  282 TYR A CD1 1 
ATOM 1853 C CD2 . TYR A 1 300 ? 101.037 95.338  106.723 1.00 224.95 ?  282 TYR A CD2 1 
ATOM 1854 C CE1 . TYR A 1 300 ? 99.592  97.663  106.954 1.00 224.95 ?  282 TYR A CE1 1 
ATOM 1855 C CE2 . TYR A 1 300 ? 101.506 96.492  106.153 1.00 224.95 ?  282 TYR A CE2 1 
ATOM 1856 C CZ  . TYR A 1 300 ? 100.782 97.651  106.268 1.00 224.95 ?  282 TYR A CZ  1 
ATOM 1857 O OH  . TYR A 1 300 ? 101.262 98.798  105.689 1.00 224.95 ?  282 TYR A OH  1 
ATOM 1858 N N   . THR A 1 301 ? 98.932  91.855  110.079 1.00 234.98 ?  283 THR A N   1 
ATOM 1859 C CA  . THR A 1 301 ? 98.223  90.659  110.504 1.00 234.98 ?  283 THR A CA  1 
ATOM 1860 C C   . THR A 1 301 ? 97.907  90.646  111.982 1.00 234.98 ?  283 THR A C   1 
ATOM 1861 O O   . THR A 1 301 ? 97.430  89.618  112.471 1.00 234.98 ?  283 THR A O   1 
ATOM 1862 C CB  . THR A 1 301 ? 99.013  89.403  110.150 1.00 234.98 ?  283 THR A CB  1 
ATOM 1863 O OG1 . THR A 1 301 ? 100.094 89.238  111.076 1.00 234.98 ?  283 THR A OG1 1 
ATOM 1864 C CG2 . THR A 1 301 ? 99.540  89.484  108.727 1.00 234.98 ?  283 THR A CG2 1 
ATOM 1865 N N   . VAL A 1 302 ? 98.160  91.719  112.723 1.00 232.44 ?  284 VAL A N   1 
ATOM 1866 C CA  . VAL A 1 302 ? 97.595  91.864  114.053 1.00 232.44 ?  284 VAL A CA  1 
ATOM 1867 C C   . VAL A 1 302 ? 96.567  92.986  114.127 1.00 232.44 ?  284 VAL A C   1 
ATOM 1868 O O   . VAL A 1 302 ? 95.433  92.754  114.547 1.00 232.44 ?  284 VAL A O   1 
ATOM 1869 C CB  . VAL A 1 302 ? 98.695  92.049  115.112 1.00 232.44 ?  284 VAL A CB  1 
ATOM 1870 C CG1 . VAL A 1 302 ? 98.076  92.023  116.489 1.00 232.44 ?  284 VAL A CG1 1 
ATOM 1871 C CG2 . VAL A 1 302 ? 99.696  90.922  114.982 1.00 232.44 ?  284 VAL A CG2 1 
ATOM 1872 N N   . LEU A 1 303 ? 96.926  94.199  113.731 1.00 219.13 ?  285 LEU A N   1 
ATOM 1873 C CA  . LEU A 1 303 ? 96.049  95.343  113.927 1.00 219.13 ?  285 LEU A CA  1 
ATOM 1874 C C   . LEU A 1 303 ? 95.272  95.647  112.653 1.00 219.13 ?  285 LEU A C   1 
ATOM 1875 O O   . LEU A 1 303 ? 95.647  95.230  111.557 1.00 219.13 ?  285 LEU A O   1 
ATOM 1876 C CB  . LEU A 1 303 ? 96.848  96.575  114.362 1.00 219.13 ?  285 LEU A CB  1 
ATOM 1877 C CG  . LEU A 1 303 ? 97.232  96.614  115.843 1.00 219.13 ?  285 LEU A CG  1 
ATOM 1878 C CD1 . LEU A 1 303 ? 97.700  97.997  116.260 1.00 219.13 ?  285 LEU A CD1 1 
ATOM 1879 C CD2 . LEU A 1 303 ? 96.070  96.160  116.706 1.00 219.13 ?  285 LEU A CD2 1 
ATOM 1880 N N   . ASP A 1 304 ? 94.173  96.377  112.811 1.00 228.97 ?  286 ASP A N   1 
ATOM 1881 C CA  . ASP A 1 304 ? 93.345  96.774  111.685 1.00 228.97 ?  286 ASP A CA  1 
ATOM 1882 C C   . ASP A 1 304 ? 93.612  98.223  111.314 1.00 228.97 ?  286 ASP A C   1 
ATOM 1883 O O   . ASP A 1 304 ? 94.089  99.021  112.121 1.00 228.97 ?  286 ASP A O   1 
ATOM 1884 C CB  . ASP A 1 304 ? 91.864  96.576  111.993 1.00 228.97 ?  286 ASP A CB  1 
ATOM 1885 C CG  . ASP A 1 304 ? 91.335  95.271  111.448 1.00 228.97 ?  286 ASP A CG  1 
ATOM 1886 O OD1 . ASP A 1 304 ? 92.002  94.681  110.573 1.00 228.97 ?  286 ASP A OD1 1 
ATOM 1887 O OD2 . ASP A 1 304 ? 90.256  94.833  111.892 1.00 228.97 -1 286 ASP A OD2 1 
ATOM 1888 N N   . MET A 1 305 ? 93.270  98.558  110.073 1.00 243.31 ?  287 MET A N   1 
ATOM 1889 C CA  . MET A 1 305 ? 93.766  99.790  109.475 1.00 243.31 ?  287 MET A CA  1 
ATOM 1890 C C   . MET A 1 305 ? 93.251  101.020 110.206 1.00 243.31 ?  287 MET A C   1 
ATOM 1891 O O   . MET A 1 305 ? 94.017  101.952 110.481 1.00 243.31 ?  287 MET A O   1 
ATOM 1892 C CB  . MET A 1 305 ? 93.382  99.847  108.004 1.00 243.31 ?  287 MET A CB  1 
ATOM 1893 C CG  . MET A 1 305 ? 93.821  101.123 107.339 1.00 243.31 ?  287 MET A CG  1 
ATOM 1894 S SD  . MET A 1 305 ? 93.860  100.989 105.550 1.00 243.31 ?  287 MET A SD  1 
ATOM 1895 C CE  . MET A 1 305 ? 94.057  102.708 105.116 1.00 243.31 ?  287 MET A CE  1 
ATOM 1896 N N   . ARG A 1 306 ? 91.953  101.057 110.504 1.00 264.92 ?  288 ARG A N   1 
ATOM 1897 C CA  . ARG A 1 306 ? 91.399  102.208 111.205 1.00 264.92 ?  288 ARG A CA  1 
ATOM 1898 C C   . ARG A 1 306 ? 92.155  102.492 112.491 1.00 264.92 ?  288 ARG A C   1 
ATOM 1899 O O   . ARG A 1 306 ? 92.382  103.657 112.837 1.00 264.92 ?  288 ARG A O   1 
ATOM 1900 C CB  . ARG A 1 306 ? 89.922  101.980 111.513 1.00 264.92 ?  288 ARG A CB  1 
ATOM 1901 C CG  . ARG A 1 306 ? 89.064  101.661 110.305 1.00 264.92 ?  288 ARG A CG  1 
ATOM 1902 C CD  . ARG A 1 306 ? 87.956  100.688 110.683 1.00 264.92 ?  288 ARG A CD  1 
ATOM 1903 N NE  . ARG A 1 306 ? 86.822  100.734 109.763 1.00 264.92 ?  288 ARG A NE  1 
ATOM 1904 C CZ  . ARG A 1 306 ? 85.773  99.920  109.833 1.00 264.92 ?  288 ARG A CZ  1 
ATOM 1905 N NH1 . ARG A 1 306 ? 85.711  99.001  110.784 1.00 264.92 1  288 ARG A NH1 1 
ATOM 1906 N NH2 . ARG A 1 306 ? 84.779  100.034 108.963 1.00 264.92 ?  288 ARG A NH2 1 
ATOM 1907 N N   . ASP A 1 307 ? 92.568  101.445 113.201 1.00 247.56 ?  289 ASP A N   1 
ATOM 1908 C CA  . ASP A 1 307 ? 93.306  101.632 114.443 1.00 247.56 ?  289 ASP A CA  1 
ATOM 1909 C C   . ASP A 1 307 ? 94.607  102.374 114.185 1.00 247.56 ?  289 ASP A C   1 
ATOM 1910 O O   . ASP A 1 307 ? 94.903  103.388 114.827 1.00 247.56 ?  289 ASP A O   1 
ATOM 1911 C CB  . ASP A 1 307 ? 93.583  100.276 115.076 1.00 247.56 ?  289 ASP A CB  1 
ATOM 1912 C CG  . ASP A 1 307 ? 92.507  99.275  114.767 1.00 247.56 ?  289 ASP A CG  1 
ATOM 1913 O OD1 . ASP A 1 307 ? 91.322  99.659  114.774 1.00 247.56 ?  289 ASP A OD1 1 
ATOM 1914 O OD2 . ASP A 1 307 ? 92.846  98.104  114.514 1.00 247.56 -1 289 ASP A OD2 1 
ATOM 1915 N N   . ILE A 1 308 ? 95.399  101.869 113.239 1.00 243.72 ?  290 ILE A N   1 
ATOM 1916 C CA  . ILE A 1 308 ? 96.663  102.509 112.890 1.00 243.72 ?  290 ILE A CA  1 
ATOM 1917 C C   . ILE A 1 308 ? 96.432  103.964 112.530 1.00 243.72 ?  290 ILE A C   1 
ATOM 1918 O O   . ILE A 1 308 ? 97.131  104.862 113.011 1.00 243.72 ?  290 ILE A O   1 
ATOM 1919 C CB  . ILE A 1 308 ? 97.340  101.753 111.736 1.00 243.72 ?  290 ILE A CB  1 
ATOM 1920 C CG1 . ILE A 1 308 ? 97.613  100.306 112.132 1.00 243.72 ?  290 ILE A CG1 1 
ATOM 1921 C CG2 . ILE A 1 308 ? 98.613  102.446 111.334 1.00 243.72 ?  290 ILE A CG2 1 
ATOM 1922 C CD1 . ILE A 1 308 ? 98.311  100.166 113.454 1.00 243.72 ?  290 ILE A CD1 1 
ATOM 1923 N N   . LEU A 1 309 ? 95.441  104.218 111.681 1.00 253.67 ?  291 LEU A N   1 
ATOM 1924 C CA  . LEU A 1 309 ? 95.133  105.588 111.300 1.00 253.67 ?  291 LEU A CA  1 
ATOM 1925 C C   . LEU A 1 309 ? 94.803  106.432 112.521 1.00 253.67 ?  291 LEU A C   1 
ATOM 1926 O O   . LEU A 1 309 ? 95.098  107.631 112.559 1.00 253.67 ?  291 LEU A O   1 
ATOM 1927 C CB  . LEU A 1 309 ? 93.975  105.590 110.314 1.00 253.67 ?  291 LEU A CB  1 
ATOM 1928 C CG  . LEU A 1 309 ? 94.329  104.833 109.040 1.00 253.67 ?  291 LEU A CG  1 
ATOM 1929 C CD1 . LEU A 1 309 ? 93.115  104.673 108.151 1.00 253.67 ?  291 LEU A CD1 1 
ATOM 1930 C CD2 . LEU A 1 309 ? 95.437  105.559 108.318 1.00 253.67 ?  291 LEU A CD2 1 
ATOM 1931 N N   . ALA A 1 310 ? 94.197  105.819 113.533 1.00 264.69 ?  292 ALA A N   1 
ATOM 1932 C CA  . ALA A 1 310 ? 93.888  106.526 114.765 1.00 264.69 ?  292 ALA A CA  1 
ATOM 1933 C C   . ALA A 1 310 ? 95.061  106.534 115.732 1.00 264.69 ?  292 ALA A C   1 
ATOM 1934 O O   . ALA A 1 310 ? 95.384  107.580 116.303 1.00 264.69 ?  292 ALA A O   1 
ATOM 1935 C CB  . ALA A 1 310 ? 92.667  105.899 115.438 1.00 264.69 ?  292 ALA A CB  1 
ATOM 1936 N N   . SER A 1 311 ? 95.707  105.386 115.922 1.00 253.01 ?  293 SER A N   1 
ATOM 1937 C CA  . SER A 1 311 ? 96.796  105.284 116.881 1.00 253.01 ?  293 SER A CA  1 
ATOM 1938 C C   . SER A 1 311 ? 97.928  106.238 116.531 1.00 253.01 ?  293 SER A C   1 
ATOM 1939 O O   . SER A 1 311 ? 98.026  106.739 115.409 1.00 253.01 ?  293 SER A O   1 
ATOM 1940 C CB  . SER A 1 311 ? 97.330  103.858 116.926 1.00 253.01 ?  293 SER A CB  1 
ATOM 1941 O OG  . SER A 1 311 ? 98.474  103.789 117.752 1.00 253.01 ?  293 SER A OG  1 
ATOM 1942 N N   . ASP A 1 312 ? 98.792  106.489 117.515 1.00 253.14 ?  294 ASP A N   1 
ATOM 1943 C CA  . ASP A 1 312 ? 99.954  107.342 117.322 1.00 253.14 ?  294 ASP A CA  1 
ATOM 1944 C C   . ASP A 1 312 ? 101.266 106.690 117.724 1.00 253.14 ?  294 ASP A C   1 
ATOM 1945 O O   . ASP A 1 312 ? 102.317 107.106 117.230 1.00 253.14 ?  294 ASP A O   1 
ATOM 1946 C CB  . ASP A 1 312 ? 99.791  108.652 118.103 1.00 253.14 ?  294 ASP A CB  1 
ATOM 1947 C CG  . ASP A 1 312 ? 98.945  109.662 117.364 1.00 253.14 ?  294 ASP A CG  1 
ATOM 1948 O OD1 . ASP A 1 312 ? 99.156  110.875 117.562 1.00 253.14 ?  294 ASP A OD1 1 
ATOM 1949 O OD2 . ASP A 1 312 ? 98.067  109.245 116.581 1.00 253.14 -1 294 ASP A OD2 1 
ATOM 1950 N N   . ALA A 1 313 ? 101.236 105.696 118.603 1.00 212.09 ?  295 ALA A N   1 
ATOM 1951 C CA  . ALA A 1 313 ? 102.396 104.866 118.907 1.00 212.09 ?  295 ALA A CA  1 
ATOM 1952 C C   . ALA A 1 313 ? 102.008 103.454 118.491 1.00 212.09 ?  295 ALA A C   1 
ATOM 1953 O O   . ALA A 1 313 ? 101.502 102.678 119.302 1.00 212.09 ?  295 ALA A O   1 
ATOM 1954 C CB  . ALA A 1 313 ? 102.777 104.947 120.368 1.00 212.09 ?  295 ALA A CB  1 
ATOM 1955 N N   . VAL A 1 314 ? 102.247 103.133 117.219 1.00 202.76 ?  296 VAL A N   1 
ATOM 1956 C CA  . VAL A 1 314 ? 101.727 101.904 116.631 1.00 202.76 ?  296 VAL A CA  1 
ATOM 1957 C C   . VAL A 1 314 ? 102.047 100.695 117.493 1.00 202.76 ?  296 VAL A C   1 
ATOM 1958 O O   . VAL A 1 314 ? 101.221 99.782  117.635 1.00 202.76 ?  296 VAL A O   1 
ATOM 1959 C CB  . VAL A 1 314 ? 102.285 101.747 115.210 1.00 202.76 ?  296 VAL A CB  1 
ATOM 1960 C CG1 . VAL A 1 314 ? 101.743 102.833 114.328 1.00 202.76 ?  296 VAL A CG1 1 
ATOM 1961 C CG2 . VAL A 1 314 ? 103.778 101.844 115.240 1.00 202.76 ?  296 VAL A CG2 1 
ATOM 1962 N N   . ALA A 1 315 ? 103.222 100.686 118.118 1.00 215.52 ?  297 ALA A N   1 
ATOM 1963 C CA  . ALA A 1 315 ? 103.686 99.481  118.790 1.00 215.52 ?  297 ALA A CA  1 
ATOM 1964 C C   . ALA A 1 315 ? 102.886 99.190  120.053 1.00 215.52 ?  297 ALA A C   1 
ATOM 1965 O O   . ALA A 1 315 ? 102.559 98.031  120.329 1.00 215.52 ?  297 ALA A O   1 
ATOM 1966 C CB  . ALA A 1 315 ? 105.170 99.604  119.114 1.00 215.52 ?  297 ALA A CB  1 
ATOM 1967 N N   . VAL A 1 316 ? 102.566 100.215 120.843 1.00 218.05 ?  298 VAL A N   1 
ATOM 1968 C CA  . VAL A 1 316 ? 101.860 99.909  122.080 1.00 218.05 ?  298 VAL A CA  1 
ATOM 1969 C C   . VAL A 1 316 ? 100.456 99.415  121.783 1.00 218.05 ?  298 VAL A C   1 
ATOM 1970 O O   . VAL A 1 316 ? 99.950  98.543  122.487 1.00 218.05 ?  298 VAL A O   1 
ATOM 1971 C CB  . VAL A 1 316 ? 101.846 101.109 123.042 1.00 218.05 ?  298 VAL A CB  1 
ATOM 1972 C CG1 . VAL A 1 316 ? 103.214 101.291 123.674 1.00 218.05 ?  298 VAL A CG1 1 
ATOM 1973 C CG2 . VAL A 1 316 ? 101.411 102.356 122.334 1.00 218.05 ?  298 VAL A CG2 1 
ATOM 1974 N N   . THR A 1 317 ? 99.810  99.935  120.742 1.00 216.31 ?  299 THR A N   1 
ATOM 1975 C CA  . THR A 1 317 ? 98.508  99.401  120.360 1.00 216.31 ?  299 THR A CA  1 
ATOM 1976 C C   . THR A 1 317 ? 98.630  97.969  119.870 1.00 216.31 ?  299 THR A C   1 
ATOM 1977 O O   . THR A 1 317 ? 97.817  97.105  120.230 1.00 216.31 ?  299 THR A O   1 
ATOM 1978 C CB  . THR A 1 317 ? 97.887  100.271 119.281 1.00 216.31 ?  299 THR A CB  1 
ATOM 1979 O OG1 . THR A 1 317 ? 98.803  100.379 118.185 1.00 216.31 ?  299 THR A OG1 1 
ATOM 1980 C CG2 . THR A 1 317 ? 97.601  101.640 119.833 1.00 216.31 ?  299 THR A CG2 1 
ATOM 1981 N N   . PHE A 1 318 ? 99.620  97.716  119.015 1.00 214.18 ?  300 PHE A N   1 
ATOM 1982 C CA  . PHE A 1 318 ? 99.961  96.348  118.656 1.00 214.18 ?  300 PHE A CA  1 
ATOM 1983 C C   . PHE A 1 318 ? 100.014 95.463  119.890 1.00 214.18 ?  300 PHE A C   1 
ATOM 1984 O O   . PHE A 1 318 ? 99.459  94.360  119.904 1.00 214.18 ?  300 PHE A O   1 
ATOM 1985 C CB  . PHE A 1 318 ? 101.302 96.349  117.930 1.00 214.18 ?  300 PHE A CB  1 
ATOM 1986 C CG  . PHE A 1 318 ? 101.664 95.044  117.299 1.00 214.18 ?  300 PHE A CG  1 
ATOM 1987 C CD1 . PHE A 1 318 ? 101.449 94.833  115.953 1.00 214.18 ?  300 PHE A CD1 1 
ATOM 1988 C CD2 . PHE A 1 318 ? 102.256 94.043  118.040 1.00 214.18 ?  300 PHE A CD2 1 
ATOM 1989 C CE1 . PHE A 1 318 ? 101.803 93.646  115.362 1.00 214.18 ?  300 PHE A CE1 1 
ATOM 1990 C CE2 . PHE A 1 318 ? 102.605 92.850  117.452 1.00 214.18 ?  300 PHE A CE2 1 
ATOM 1991 C CZ  . PHE A 1 318 ? 102.381 92.653  116.111 1.00 214.18 ?  300 PHE A CZ  1 
ATOM 1992 N N   . ALA A 1 319 ? 100.660 95.949  120.947 1.00 222.13 ?  301 ALA A N   1 
ATOM 1993 C CA  . ALA A 1 319 ? 100.753 95.187  122.186 1.00 222.13 ?  301 ALA A CA  1 
ATOM 1994 C C   . ALA A 1 319 ? 99.380  94.995  122.813 1.00 222.13 ?  301 ALA A C   1 
ATOM 1995 O O   . ALA A 1 319 ? 98.940  93.864  123.049 1.00 222.13 ?  301 ALA A O   1 
ATOM 1996 C CB  . ALA A 1 319 ? 101.691 95.892  123.161 1.00 222.13 ?  301 ALA A CB  1 
ATOM 1997 N N   . ASP A 1 320 ? 98.686  96.105  123.082 1.00 229.54 ?  302 ASP A N   1 
ATOM 1998 C CA  . ASP A 1 320 ? 97.374  96.062  123.713 1.00 229.54 ?  302 ASP A CA  1 
ATOM 1999 C C   . ASP A 1 320 ? 96.452  95.083  123.027 1.00 229.54 ?  302 ASP A C   1 
ATOM 2000 O O   . ASP A 1 320 ? 95.509  94.583  123.647 1.00 229.54 ?  302 ASP A O   1 
ATOM 2001 C CB  . ASP A 1 320 ? 96.714  97.436  123.722 1.00 229.54 ?  302 ASP A CB  1 
ATOM 2002 C CG  . ASP A 1 320 ? 97.622  98.512  124.249 1.00 229.54 ?  302 ASP A CG  1 
ATOM 2003 O OD1 . ASP A 1 320 ? 97.825  99.516  123.537 1.00 229.54 ?  302 ASP A OD1 1 
ATOM 2004 O OD2 . ASP A 1 320 ? 98.146  98.346  125.370 1.00 229.54 -1 302 ASP A OD2 1 
ATOM 2005 N N   . GLN A 1 321 ? 96.703  94.802  121.760 1.00 229.53 ?  303 GLN A N   1 
ATOM 2006 C CA  . GLN A 1 321 ? 95.904  93.791  121.095 1.00 229.53 ?  303 GLN A CA  1 
ATOM 2007 C C   . GLN A 1 321 ? 96.118  92.410  121.710 1.00 229.53 ?  303 GLN A C   1 
ATOM 2008 O O   . GLN A 1 321 ? 95.171  91.622  121.808 1.00 229.53 ?  303 GLN A O   1 
ATOM 2009 C CB  . GLN A 1 321 ? 96.228  93.775  119.607 1.00 229.53 ?  303 GLN A CB  1 
ATOM 2010 C CG  . GLN A 1 321 ? 95.411  92.771  118.834 1.00 229.53 ?  303 GLN A CG  1 
ATOM 2011 C CD  . GLN A 1 321 ? 93.942  92.829  119.198 1.00 229.53 ?  303 GLN A CD  1 
ATOM 2012 O OE1 . GLN A 1 321 ? 93.356  93.909  119.294 1.00 229.53 ?  303 GLN A OE1 1 
ATOM 2013 N NE2 . GLN A 1 321 ? 93.337  91.665  119.410 1.00 229.53 ?  303 GLN A NE2 1 
ATOM 2014 N N   . ILE A 1 322 ? 97.336  92.100  122.155 1.00 219.18 ?  304 ILE A N   1 
ATOM 2015 C CA  . ILE A 1 322 ? 97.753  90.700  122.193 1.00 219.18 ?  304 ILE A CA  1 
ATOM 2016 C C   . ILE A 1 322 ? 98.133  90.143  123.561 1.00 219.18 ?  304 ILE A C   1 
ATOM 2017 O O   . ILE A 1 322 ? 98.241  88.923  123.722 1.00 219.18 ?  304 ILE A O   1 
ATOM 2018 C CB  . ILE A 1 322 ? 98.936  90.495  121.237 1.00 219.18 ?  304 ILE A CB  1 
ATOM 2019 C CG1 . ILE A 1 322 ? 100.206 91.040  121.880 1.00 219.18 ?  304 ILE A CG1 1 
ATOM 2020 C CG2 . ILE A 1 322 ? 98.680  91.188  119.923 1.00 219.18 ?  304 ILE A CG2 1 
ATOM 2021 C CD1 . ILE A 1 322 ? 101.461 90.488  121.277 1.00 219.18 ?  304 ILE A CD1 1 
ATOM 2022 N N   . PHE A 1 323 ? 98.343  90.997  124.553 1.00 229.05 ?  305 PHE A N   1 
ATOM 2023 C CA  . PHE A 1 323 ? 99.072  90.592  125.752 1.00 229.05 ?  305 PHE A CA  1 
ATOM 2024 C C   . PHE A 1 323 ? 98.222  90.806  127.002 1.00 229.05 ?  305 PHE A C   1 
ATOM 2025 O O   . PHE A 1 323 ? 97.003  91.004  126.942 1.00 229.05 ?  305 PHE A O   1 
ATOM 2026 C CB  . PHE A 1 323 ? 100.399 91.351  125.844 1.00 229.05 ?  305 PHE A CB  1 
ATOM 2027 C CG  . PHE A 1 323 ? 101.523 90.682  125.132 1.00 229.05 ?  305 PHE A CG  1 
ATOM 2028 C CD1 . PHE A 1 323 ? 101.459 89.334  124.833 1.00 229.05 ?  305 PHE A CD1 1 
ATOM 2029 C CD2 . PHE A 1 323 ? 102.647 91.395  124.765 1.00 229.05 ?  305 PHE A CD2 1 
ATOM 2030 C CE1 . PHE A 1 323 ? 102.499 88.707  124.180 1.00 229.05 ?  305 PHE A CE1 1 
ATOM 2031 C CE2 . PHE A 1 323 ? 103.690 90.777  124.110 1.00 229.05 ?  305 PHE A CE2 1 
ATOM 2032 C CZ  . PHE A 1 323 ? 103.617 89.429  123.818 1.00 229.05 ?  305 PHE A CZ  1 
ATOM 2033 N N   . GLY A 1 324 ? 98.863  90.702  128.162 1.00 207.02 ?  306 GLY A N   1 
ATOM 2034 C CA  . GLY A 1 324 ? 98.248  91.061  129.423 1.00 207.02 ?  306 GLY A CA  1 
ATOM 2035 C C   . GLY A 1 324 ? 99.161  91.990  130.189 1.00 207.02 ?  306 GLY A C   1 
ATOM 2036 O O   . GLY A 1 324 ? 98.785  92.561  131.215 1.00 207.02 ?  306 GLY A O   1 
ATOM 2037 N N   . ILE A 1 325 ? 100.379 92.139  129.682 1.00 200.60 ?  307 ILE A N   1 
ATOM 2038 C CA  . ILE A 1 325 ? 101.369 93.026  130.271 1.00 200.60 ?  307 ILE A CA  1 
ATOM 2039 C C   . ILE A 1 325 ? 101.237 94.396  129.630 1.00 200.60 ?  307 ILE A C   1 
ATOM 2040 O O   . ILE A 1 325 ? 100.985 95.394  130.313 1.00 200.60 ?  307 ILE A O   1 
ATOM 2041 C CB  . ILE A 1 325 ? 102.784 92.459  130.081 1.00 200.60 ?  307 ILE A CB  1 
ATOM 2042 C CG1 . ILE A 1 325 ? 102.900 91.103  130.771 1.00 200.60 ?  307 ILE A CG1 1 
ATOM 2043 C CG2 . ILE A 1 325 ? 103.818 93.420  130.607 1.00 200.60 ?  307 ILE A CG2 1 
ATOM 2044 C CD1 . ILE A 1 325 ? 104.181 90.379  130.454 1.00 200.60 ?  307 ILE A CD1 1 
ATOM 2045 N N   . PHE A 1 326 ? 101.459 94.448  128.319 1.00 219.25 ?  308 PHE A N   1 
ATOM 2046 C CA  . PHE A 1 326 ? 101.227 95.615  127.477 1.00 219.25 ?  308 PHE A CA  1 
ATOM 2047 C C   . PHE A 1 326 ? 102.230 96.726  127.711 1.00 219.25 ?  308 PHE A C   1 
ATOM 2048 O O   . PHE A 1 326 ? 102.351 97.638  126.890 1.00 219.25 ?  308 PHE A O   1 
ATOM 2049 C CB  . PHE A 1 326 ? 99.849  96.217  127.736 1.00 219.25 ?  308 PHE A CB  1 
ATOM 2050 C CG  . PHE A 1 326 ? 98.716  95.384  127.267 1.00 219.25 ?  308 PHE A CG  1 
ATOM 2051 C CD1 . PHE A 1 326 ? 98.889  94.439  126.283 1.00 219.25 ?  308 PHE A CD1 1 
ATOM 2052 C CD2 . PHE A 1 326 ? 97.458  95.561  127.811 1.00 219.25 ?  308 PHE A CD2 1 
ATOM 2053 C CE1 . PHE A 1 326 ? 97.824  93.689  125.854 1.00 219.25 ?  308 PHE A CE1 1 
ATOM 2054 C CE2 . PHE A 1 326 ? 96.393  94.807  127.385 1.00 219.25 ?  308 PHE A CE2 1 
ATOM 2055 C CZ  . PHE A 1 326 ? 96.577  93.870  126.403 1.00 219.25 ?  308 PHE A CZ  1 
ATOM 2056 N N   . ASN A 1 327 ? 102.967 96.661  128.807 1.00 219.03 ?  309 ASN A N   1 
ATOM 2057 C CA  . ASN A 1 327 ? 103.659 97.869  129.216 1.00 219.03 ?  309 ASN A CA  1 
ATOM 2058 C C   . ASN A 1 327 ? 105.122 97.617  129.497 1.00 219.03 ?  309 ASN A C   1 
ATOM 2059 O O   . ASN A 1 327 ? 105.987 98.398  129.095 1.00 219.03 ?  309 ASN A O   1 
ATOM 2060 C CB  . ASN A 1 327 ? 102.992 98.452  130.457 1.00 219.03 ?  309 ASN A CB  1 
ATOM 2061 C CG  . ASN A 1 327 ? 103.060 97.513  131.640 1.00 219.03 ?  309 ASN A CG  1 
ATOM 2062 O OD1 . ASN A 1 327 ? 103.324 96.323  131.483 1.00 219.03 ?  309 ASN A OD1 1 
ATOM 2063 N ND2 . ASN A 1 327 ? 102.837 98.045  132.836 1.00 219.03 ?  309 ASN A ND2 1 
ATOM 2064 N N   . TRP A 1 328 ? 105.412 96.515  130.164 1.00 223.70 ?  310 TRP A N   1 
ATOM 2065 C CA  . TRP A 1 328 ? 106.746 96.334  130.698 1.00 223.70 ?  310 TRP A CA  1 
ATOM 2066 C C   . TRP A 1 328 ? 107.761 96.052  129.620 1.00 223.70 ?  310 TRP A C   1 
ATOM 2067 O O   . TRP A 1 328 ? 108.903 95.710  129.937 1.00 223.70 ?  310 TRP A O   1 
ATOM 2068 C CB  . TRP A 1 328 ? 106.746 95.220  131.740 1.00 223.70 ?  310 TRP A CB  1 
ATOM 2069 C CG  . TRP A 1 328 ? 106.346 95.720  133.076 1.00 223.70 ?  310 TRP A CG  1 
ATOM 2070 C CD1 . TRP A 1 328 ? 105.763 96.918  133.354 1.00 223.70 ?  310 TRP A CD1 1 
ATOM 2071 C CD2 . TRP A 1 328 ? 106.511 95.051  134.328 1.00 223.70 ?  310 TRP A CD2 1 
ATOM 2072 N NE1 . TRP A 1 328 ? 105.545 97.037  134.703 1.00 223.70 ?  310 TRP A NE1 1 
ATOM 2073 C CE2 . TRP A 1 328 ? 105.996 95.903  135.325 1.00 223.70 ?  310 TRP A CE2 1 
ATOM 2074 C CE3 . TRP A 1 328 ? 107.039 93.814  134.704 1.00 223.70 ?  310 TRP A CE3 1 
ATOM 2075 C CZ2 . TRP A 1 328 ? 105.995 95.556  136.673 1.00 223.70 ?  310 TRP A CZ2 1 
ATOM 2076 C CZ3 . TRP A 1 328 ? 107.037 93.471  136.044 1.00 223.70 ?  310 TRP A CZ3 1 
ATOM 2077 C CH2 . TRP A 1 328 ? 106.518 94.339  137.012 1.00 223.70 ?  310 TRP A CH2 1 
ATOM 2078 N N   . ILE A 1 329 ? 107.376 96.168  128.355 1.00 214.74 ?  311 ILE A N   1 
ATOM 2079 C CA  . ILE A 1 329 ? 108.329 95.944  127.286 1.00 214.74 ?  311 ILE A CA  1 
ATOM 2080 C C   . ILE A 1 329 ? 108.369 97.134  126.340 1.00 214.74 ?  311 ILE A C   1 
ATOM 2081 O O   . ILE A 1 329 ? 109.363 97.862  126.285 1.00 214.74 ?  311 ILE A O   1 
ATOM 2082 C CB  . ILE A 1 329 ? 107.997 94.651  126.524 1.00 214.74 ?  311 ILE A CB  1 
ATOM 2083 C CG1 . ILE A 1 329 ? 107.884 93.463  127.487 1.00 214.74 ?  311 ILE A CG1 1 
ATOM 2084 C CG2 . ILE A 1 329 ? 109.052 94.382  125.477 1.00 214.74 ?  311 ILE A CG2 1 
ATOM 2085 C CD1 . ILE A 1 329 ? 106.491 93.231  128.064 1.00 214.74 ?  311 ILE A CD1 1 
ATOM 2086 N N   . ILE A 1 330 ? 107.272 97.374  125.637 1.00 201.27 ?  312 ILE A N   1 
ATOM 2087 C CA  . ILE A 1 330 ? 107.314 98.191  124.428 1.00 201.27 ?  312 ILE A CA  1 
ATOM 2088 C C   . ILE A 1 330 ? 107.671 99.638  124.733 1.00 201.27 ?  312 ILE A C   1 
ATOM 2089 O O   . ILE A 1 330 ? 108.698 100.128 124.237 1.00 201.27 ?  312 ILE A O   1 
ATOM 2090 C CB  . ILE A 1 330 ? 105.987 98.123  123.665 1.00 201.27 ?  312 ILE A CB  1 
ATOM 2091 C CG1 . ILE A 1 330 ? 105.749 96.712  123.147 1.00 201.27 ?  312 ILE A CG1 1 
ATOM 2092 C CG2 . ILE A 1 330 ? 105.993 99.122  122.543 1.00 201.27 ?  312 ILE A CG2 1 
ATOM 2093 C CD1 . ILE A 1 330 ? 105.027 95.824  124.128 1.00 201.27 ?  312 ILE A CD1 1 
ATOM 2094 N N   . PRO A 1 331 ? 106.867 100.361 125.514 1.00 198.82 ?  313 PRO A N   1 
ATOM 2095 C CA  . PRO A 1 331 ? 107.092 101.808 125.607 1.00 198.82 ?  313 PRO A CA  1 
ATOM 2096 C C   . PRO A 1 331 ? 108.484 102.159 126.085 1.00 198.82 ?  313 PRO A C   1 
ATOM 2097 O O   . PRO A 1 331 ? 109.179 102.935 125.423 1.00 198.82 ?  313 PRO A O   1 
ATOM 2098 C CB  . PRO A 1 331 ? 106.011 102.259 126.590 1.00 198.82 ?  313 PRO A CB  1 
ATOM 2099 C CG  . PRO A 1 331 ? 105.725 101.069 127.391 1.00 198.82 ?  313 PRO A CG  1 
ATOM 2100 C CD  . PRO A 1 331 ? 105.818 99.929  126.450 1.00 198.82 ?  313 PRO A CD  1 
ATOM 2101 N N   . LEU A 1 332 ? 108.928 101.579 127.199 1.00 221.66 ?  314 LEU A N   1 
ATOM 2102 C CA  . LEU A 1 332 ? 110.220 101.962 127.757 1.00 221.66 ?  314 LEU A CA  1 
ATOM 2103 C C   . LEU A 1 332 ? 111.367 101.532 126.854 1.00 221.66 ?  314 LEU A C   1 
ATOM 2104 O O   . LEU A 1 332 ? 112.352 102.264 126.697 1.00 221.66 ?  314 LEU A O   1 
ATOM 2105 C CB  . LEU A 1 332 ? 110.382 101.374 129.157 1.00 221.66 ?  314 LEU A CB  1 
ATOM 2106 C CG  . LEU A 1 332 ? 109.844 102.202 130.332 1.00 221.66 ?  314 LEU A CG  1 
ATOM 2107 C CD1 . LEU A 1 332 ? 110.632 103.491 130.491 1.00 221.66 ?  314 LEU A CD1 1 
ATOM 2108 C CD2 . LEU A 1 332 ? 108.358 102.508 130.186 1.00 221.66 ?  314 LEU A CD2 1 
ATOM 2109 N N   . SER A 1 333 ? 111.268 100.343 126.264 1.00 209.52 ?  315 SER A N   1 
ATOM 2110 C CA  . SER A 1 333 ? 112.315 99.891  125.358 1.00 209.52 ?  315 SER A CA  1 
ATOM 2111 C C   . SER A 1 333 ? 112.484 100.860 124.204 1.00 209.52 ?  315 SER A C   1 
ATOM 2112 O O   . SER A 1 333 ? 113.587 101.358 123.944 1.00 209.52 ?  315 SER A O   1 
ATOM 2113 C CB  . SER A 1 333 ? 111.979 98.509  124.821 1.00 209.52 ?  315 SER A CB  1 
ATOM 2114 O OG  . SER A 1 333 ? 110.831 98.596  123.998 1.00 209.52 ?  315 SER A OG  1 
ATOM 2115 N N   . VAL A 1 334 ? 111.395 101.127 123.489 1.00 200.78 ?  316 VAL A N   1 
ATOM 2116 C CA  . VAL A 1 334 ? 111.496 102.053 122.379 1.00 200.78 ?  316 VAL A CA  1 
ATOM 2117 C C   . VAL A 1 334 ? 111.945 103.412 122.865 1.00 200.78 ?  316 VAL A C   1 
ATOM 2118 O O   . VAL A 1 334 ? 112.669 104.120 122.161 1.00 200.78 ?  316 VAL A O   1 
ATOM 2119 C CB  . VAL A 1 334 ? 110.161 102.137 121.642 1.00 200.78 ?  316 VAL A CB  1 
ATOM 2120 C CG1 . VAL A 1 334 ? 110.329 102.943 120.390 1.00 200.78 ?  316 VAL A CG1 1 
ATOM 2121 C CG2 . VAL A 1 334 ? 109.685 100.751 121.318 1.00 200.78 ?  316 VAL A CG2 1 
ATOM 2122 N N   . ALA A 1 335 ? 111.541 103.798 124.069 1.00 196.11 ?  317 ALA A N   1 
ATOM 2123 C CA  . ALA A 1 335 ? 112.015 105.052 124.624 1.00 196.11 ?  317 ALA A CA  1 
ATOM 2124 C C   . ALA A 1 335 ? 113.532 105.077 124.658 1.00 196.11 ?  317 ALA A C   1 
ATOM 2125 O O   . ALA A 1 335 ? 114.163 105.994 124.124 1.00 196.11 ?  317 ALA A O   1 
ATOM 2126 C CB  . ALA A 1 335 ? 111.437 105.249 126.021 1.00 196.11 ?  317 ALA A CB  1 
ATOM 2127 N N   . LEU A 1 336 ? 114.133 104.050 125.253 1.00 197.81 ?  318 LEU A N   1 
ATOM 2128 C CA  . LEU A 1 336 ? 115.585 104.023 125.379 1.00 197.81 ?  318 LEU A CA  1 
ATOM 2129 C C   . LEU A 1 336 ? 116.259 103.975 124.019 1.00 197.81 ?  318 LEU A C   1 
ATOM 2130 O O   . LEU A 1 336 ? 117.342 104.540 123.828 1.00 197.81 ?  318 LEU A O   1 
ATOM 2131 C CB  . LEU A 1 336 ? 116.015 102.833 126.223 1.00 197.81 ?  318 LEU A CB  1 
ATOM 2132 C CG  . LEU A 1 336 ? 115.563 102.947 127.670 1.00 197.81 ?  318 LEU A CG  1 
ATOM 2133 C CD1 . LEU A 1 336 ? 116.229 101.877 128.497 1.00 197.81 ?  318 LEU A CD1 1 
ATOM 2134 C CD2 . LEU A 1 336 ? 115.874 104.323 128.219 1.00 197.81 ?  318 LEU A CD2 1 
ATOM 2135 N N   . SER A 1 337 ? 115.639 103.303 123.059 1.00 200.11 ?  319 SER A N   1 
ATOM 2136 C CA  . SER A 1 337 ? 116.298 103.183 121.766 1.00 200.11 ?  319 SER A CA  1 
ATOM 2137 C C   . SER A 1 337 ? 116.264 104.501 121.009 1.00 200.11 ?  319 SER A C   1 
ATOM 2138 O O   . SER A 1 337 ? 117.290 104.936 120.471 1.00 200.11 ?  319 SER A O   1 
ATOM 2139 C CB  . SER A 1 337 ? 115.662 102.064 120.960 1.00 200.11 ?  319 SER A CB  1 
ATOM 2140 O OG  . SER A 1 337 ? 116.150 100.828 121.434 1.00 200.11 ?  319 SER A OG  1 
ATOM 2141 N N   . CYS A 1 338 ? 115.098 105.144 120.943 1.00 191.39 ?  320 CYS A N   1 
ATOM 2142 C CA  . CYS A 1 338 ? 115.056 106.499 120.415 1.00 191.39 ?  320 CYS A CA  1 
ATOM 2143 C C   . CYS A 1 338 ? 116.051 107.378 121.141 1.00 191.39 ?  320 CYS A C   1 
ATOM 2144 O O   . CYS A 1 338 ? 116.730 108.208 120.527 1.00 191.39 ?  320 CYS A O   1 
ATOM 2145 C CB  . CYS A 1 338 ? 113.654 107.084 120.541 1.00 191.39 ?  320 CYS A CB  1 
ATOM 2146 S SG  . CYS A 1 338 ? 112.316 106.024 119.995 1.00 191.39 ?  320 CYS A SG  1 
ATOM 2147 N N   . PHE A 1 339 ? 116.166 107.183 122.449 1.00 182.97 ?  321 PHE A N   1 
ATOM 2148 C CA  . PHE A 1 339 ? 117.095 107.958 123.249 1.00 182.97 ?  321 PHE A CA  1 
ATOM 2149 C C   . PHE A 1 339 ? 118.504 107.857 122.688 1.00 182.97 ?  321 PHE A C   1 
ATOM 2150 O O   . PHE A 1 339 ? 119.087 108.852 122.236 1.00 182.97 ?  321 PHE A O   1 
ATOM 2151 C CB  . PHE A 1 339 ? 117.047 107.437 124.680 1.00 182.97 ?  321 PHE A CB  1 
ATOM 2152 C CG  . PHE A 1 339 ? 117.394 108.446 125.707 1.00 182.97 ?  321 PHE A CG  1 
ATOM 2153 C CD1 . PHE A 1 339 ? 116.427 109.268 126.230 1.00 182.97 ?  321 PHE A CD1 1 
ATOM 2154 C CD2 . PHE A 1 339 ? 118.685 108.573 126.155 1.00 182.97 ?  321 PHE A CD2 1 
ATOM 2155 C CE1 . PHE A 1 339 ? 116.743 110.194 127.183 1.00 182.97 ?  321 PHE A CE1 1 
ATOM 2156 C CE2 . PHE A 1 339 ? 119.003 109.501 127.106 1.00 182.97 ?  321 PHE A CE2 1 
ATOM 2157 C CZ  . PHE A 1 339 ? 118.032 110.312 127.620 1.00 182.97 ?  321 PHE A CZ  1 
ATOM 2158 N N   . GLY A 1 340 ? 119.053 106.648 122.689 1.00 184.88 ?  322 GLY A N   1 
ATOM 2159 C CA  . GLY A 1 340 ? 120.425 106.474 122.251 1.00 184.88 ?  322 GLY A CA  1 
ATOM 2160 C C   . GLY A 1 340 ? 120.639 106.902 120.816 1.00 184.88 ?  322 GLY A C   1 
ATOM 2161 O O   . GLY A 1 340 ? 121.670 107.490 120.482 1.00 184.88 ?  322 GLY A O   1 
ATOM 2162 N N   . GLY A 1 341 ? 119.682 106.596 119.944 1.00 170.39 ?  323 GLY A N   1 
ATOM 2163 C CA  . GLY A 1 341 ? 119.838 106.980 118.556 1.00 170.39 ?  323 GLY A CA  1 
ATOM 2164 C C   . GLY A 1 341 ? 119.939 108.479 118.396 1.00 170.39 ?  323 GLY A C   1 
ATOM 2165 O O   . GLY A 1 341 ? 120.786 108.981 117.655 1.00 170.39 ?  323 GLY A O   1 
ATOM 2166 N N   . LEU A 1 342 ? 119.076 109.213 119.090 1.00 165.60 ?  324 LEU A N   1 
ATOM 2167 C CA  . LEU A 1 342 ? 119.194 110.658 119.101 1.00 165.60 ?  324 LEU A CA  1 
ATOM 2168 C C   . LEU A 1 342 ? 120.565 111.073 119.605 1.00 165.60 ?  324 LEU A C   1 
ATOM 2169 O O   . LEU A 1 342 ? 121.236 111.930 119.007 1.00 165.60 ?  324 LEU A O   1 
ATOM 2170 C CB  . LEU A 1 342 ? 118.090 111.240 119.970 1.00 165.60 ?  324 LEU A CB  1 
ATOM 2171 C CG  . LEU A 1 342 ? 118.224 112.690 120.385 1.00 165.60 ?  324 LEU A CG  1 
ATOM 2172 C CD1 . LEU A 1 342 ? 118.397 113.562 119.172 1.00 165.60 ?  324 LEU A CD1 1 
ATOM 2173 C CD2 . LEU A 1 342 ? 116.984 113.080 121.132 1.00 165.60 ?  324 LEU A CD2 1 
ATOM 2174 N N   . ASN A 1 343 ? 120.998 110.460 120.705 1.00 176.15 ?  325 ASN A N   1 
ATOM 2175 C CA  . ASN A 1 343 ? 122.284 110.816 121.287 1.00 176.15 ?  325 ASN A CA  1 
ATOM 2176 C C   . ASN A 1 343 ? 123.391 110.720 120.254 1.00 176.15 ?  325 ASN A C   1 
ATOM 2177 O O   . ASN A 1 343 ? 124.159 111.665 120.054 1.00 176.15 ?  325 ASN A O   1 
ATOM 2178 C CB  . ASN A 1 343 ? 122.600 109.911 122.467 1.00 176.15 ?  325 ASN A CB  1 
ATOM 2179 C CG  . ASN A 1 343 ? 124.052 109.977 122.854 1.00 176.15 ?  325 ASN A CG  1 
ATOM 2180 O OD1 . ASN A 1 343 ? 124.587 111.052 123.108 1.00 176.15 ?  325 ASN A OD1 1 
ATOM 2181 N ND2 . ASN A 1 343 ? 124.708 108.828 122.879 1.00 176.15 ?  325 ASN A ND2 1 
ATOM 2182 N N   . ALA A 1 344 ? 123.476 109.581 119.579 1.00 170.68 ?  326 ALA A N   1 
ATOM 2183 C CA  . ALA A 1 344 ? 124.500 109.416 118.556 1.00 170.68 ?  326 ALA A CA  1 
ATOM 2184 C C   . ALA A 1 344 ? 124.325 110.442 117.452 1.00 170.68 ?  326 ALA A C   1 
ATOM 2185 O O   . ALA A 1 344 ? 125.258 111.181 117.123 1.00 170.68 ?  326 ALA A O   1 
ATOM 2186 C CB  . ALA A 1 344 ? 124.454 108.004 117.985 1.00 170.68 ?  326 ALA A CB  1 
ATOM 2187 N N   . SER A 1 345 ? 123.117 110.521 116.892 1.00 159.43 ?  327 SER A N   1 
ATOM 2188 C CA  . SER A 1 345 ? 122.853 111.432 115.789 1.00 159.43 ?  327 SER A CA  1 
ATOM 2189 C C   . SER A 1 345 ? 123.336 112.830 116.094 1.00 159.43 ?  327 SER A C   1 
ATOM 2190 O O   . SER A 1 345 ? 123.603 113.611 115.178 1.00 159.43 ?  327 SER A O   1 
ATOM 2191 C CB  . SER A 1 345 ? 121.363 111.466 115.500 1.00 159.43 ?  327 SER A CB  1 
ATOM 2192 O OG  . SER A 1 345 ? 120.689 112.013 116.611 1.00 159.43 ?  327 SER A OG  1 
ATOM 2193 N N   . ILE A 1 346 ? 123.446 113.165 117.372 1.00 148.16 ?  328 ILE A N   1 
ATOM 2194 C CA  . ILE A 1 346 ? 123.935 114.491 117.720 1.00 148.16 ?  328 ILE A CA  1 
ATOM 2195 C C   . ILE A 1 346 ? 125.346 114.721 117.190 1.00 148.16 ?  328 ILE A C   1 
ATOM 2196 O O   . ILE A 1 346 ? 125.571 115.617 116.369 1.00 148.16 ?  328 ILE A O   1 
ATOM 2197 C CB  . ILE A 1 346 ? 123.862 114.694 119.235 1.00 148.16 ?  328 ILE A CB  1 
ATOM 2198 C CG1 . ILE A 1 346 ? 122.412 114.884 119.641 1.00 148.16 ?  328 ILE A CG1 1 
ATOM 2199 C CG2 . ILE A 1 346 ? 124.675 115.886 119.632 1.00 148.16 ?  328 ILE A CG2 1 
ATOM 2200 C CD1 . ILE A 1 346 ? 122.215 114.939 121.111 1.00 148.16 ?  328 ILE A CD1 1 
ATOM 2201 N N   . VAL A 1 347 ? 126.312 113.912 117.627 1.00 146.53 ?  329 VAL A N   1 
ATOM 2202 C CA  . VAL A 1 347 ? 127.722 114.271 117.464 1.00 146.53 ?  329 VAL A CA  1 
ATOM 2203 C C   . VAL A 1 347 ? 128.076 114.502 116.000 1.00 146.53 ?  329 VAL A C   1 
ATOM 2204 O O   . VAL A 1 347 ? 129.068 115.176 115.680 1.00 146.53 ?  329 VAL A O   1 
ATOM 2205 C CB  . VAL A 1 347 ? 128.614 113.188 118.087 1.00 146.53 ?  329 VAL A CB  1 
ATOM 2206 C CG1 . VAL A 1 347 ? 128.250 113.000 119.528 1.00 146.53 ?  329 VAL A CG1 1 
ATOM 2207 C CG2 . VAL A 1 347 ? 128.445 111.900 117.337 1.00 146.53 ?  329 VAL A CG2 1 
ATOM 2208 N N   . ALA A 1 348 ? 127.290 113.931 115.089 1.00 160.18 ?  330 ALA A N   1 
ATOM 2209 C CA  . ALA A 1 348 ? 127.503 114.199 113.676 1.00 160.18 ?  330 ALA A CA  1 
ATOM 2210 C C   . ALA A 1 348 ? 127.512 115.689 113.402 1.00 160.18 ?  330 ALA A C   1 
ATOM 2211 O O   . ALA A 1 348 ? 128.279 116.172 112.553 1.00 160.18 ?  330 ALA A O   1 
ATOM 2212 C CB  . ALA A 1 348 ? 126.420 113.515 112.850 1.00 160.18 ?  330 ALA A CB  1 
ATOM 2213 N N   . ALA A 1 349 ? 126.659 116.430 114.105 1.00 168.06 ?  331 ALA A N   1 
ATOM 2214 C CA  . ALA A 1 349 ? 126.670 117.875 113.975 1.00 168.06 ?  331 ALA A CA  1 
ATOM 2215 C C   . ALA A 1 349 ? 128.057 118.427 114.248 1.00 168.06 ?  331 ALA A C   1 
ATOM 2216 O O   . ALA A 1 349 ? 128.580 119.220 113.461 1.00 168.06 ?  331 ALA A O   1 
ATOM 2217 C CB  . ALA A 1 349 ? 125.648 118.496 114.920 1.00 168.06 ?  331 ALA A CB  1 
ATOM 2218 N N   . SER A 1 350 ? 128.671 118.009 115.350 1.00 166.18 ?  332 SER A N   1 
ATOM 2219 C CA  . SER A 1 350 ? 130.006 118.492 115.675 1.00 166.18 ?  332 SER A CA  1 
ATOM 2220 C C   . SER A 1 350 ? 130.995 118.141 114.575 1.00 166.18 ?  332 SER A C   1 
ATOM 2221 O O   . SER A 1 350 ? 131.848 118.959 114.200 1.00 166.18 ?  332 SER A O   1 
ATOM 2222 C CB  . SER A 1 350 ? 130.449 117.901 117.006 1.00 166.18 ?  332 SER A CB  1 
ATOM 2223 O OG  . SER A 1 350 ? 130.387 116.488 116.957 1.00 166.18 ?  332 SER A OG  1 
ATOM 2224 N N   . ARG A 1 351 ? 130.904 116.915 114.058 1.00 173.77 ?  333 ARG A N   1 
ATOM 2225 C CA  . ARG A 1 351 ? 131.801 116.513 112.978 1.00 173.77 ?  333 ARG A CA  1 
ATOM 2226 C C   . ARG A 1 351 ? 131.745 117.514 111.836 1.00 173.77 ?  333 ARG A C   1 
ATOM 2227 O O   . ARG A 1 351 ? 132.766 118.100 111.437 1.00 173.77 ?  333 ARG A O   1 
ATOM 2228 C CB  . ARG A 1 351 ? 131.437 115.124 112.452 1.00 173.77 ?  333 ARG A CB  1 
ATOM 2229 C CG  . ARG A 1 351 ? 131.171 114.061 113.493 1.00 173.77 ?  333 ARG A CG  1 
ATOM 2230 C CD  . ARG A 1 351 ? 130.625 112.785 112.839 1.00 173.77 ?  333 ARG A CD  1 
ATOM 2231 N NE  . ARG A 1 351 ? 131.582 112.151 111.932 1.00 173.77 ?  333 ARG A NE  1 
ATOM 2232 C CZ  . ARG A 1 351 ? 131.277 111.170 111.086 1.00 173.77 ?  333 ARG A CZ  1 
ATOM 2233 N NH1 . ARG A 1 351 ? 130.036 110.711 111.019 1.00 173.77 1  333 ARG A NH1 1 
ATOM 2234 N NH2 . ARG A 1 351 ? 132.212 110.650 110.302 1.00 173.77 ?  333 ARG A NH2 1 
ATOM 2235 N N   . LEU A 1 352 ? 130.546 117.722 111.301 1.00 173.96 ?  334 LEU A N   1 
ATOM 2236 C CA  . LEU A 1 352 ? 130.427 118.557 110.115 1.00 173.96 ?  334 LEU A CA  1 
ATOM 2237 C C   . LEU A 1 352 ? 130.785 119.995 110.438 1.00 173.96 ?  334 LEU A C   1 
ATOM 2238 O O   . LEU A 1 352 ? 131.366 120.703 109.611 1.00 173.96 ?  334 LEU A O   1 
ATOM 2239 C CB  . LEU A 1 352 ? 129.027 118.458 109.525 1.00 173.96 ?  334 LEU A CB  1 
ATOM 2240 C CG  . LEU A 1 352 ? 127.867 118.911 110.393 1.00 173.96 ?  334 LEU A CG  1 
ATOM 2241 C CD1 . LEU A 1 352 ? 127.494 120.326 110.039 1.00 173.96 ?  334 LEU A CD1 1 
ATOM 2242 C CD2 . LEU A 1 352 ? 126.694 117.982 110.202 1.00 173.96 ?  334 LEU A CD2 1 
ATOM 2243 N N   . PHE A 1 353 ? 130.447 120.444 111.643 1.00 186.71 ?  335 PHE A N   1 
ATOM 2244 C CA  . PHE A 1 353 ? 130.901 121.752 112.077 1.00 186.71 ?  335 PHE A CA  1 
ATOM 2245 C C   . PHE A 1 353 ? 132.390 121.895 111.884 1.00 186.71 ?  335 PHE A C   1 
ATOM 2246 O O   . PHE A 1 353 ? 132.853 122.832 111.229 1.00 186.71 ?  335 PHE A O   1 
ATOM 2247 C CB  . PHE A 1 353 ? 130.564 121.974 113.542 1.00 186.71 ?  335 PHE A CB  1 
ATOM 2248 C CG  . PHE A 1 353 ? 129.267 122.646 113.759 1.00 186.71 ?  335 PHE A CG  1 
ATOM 2249 C CD1 . PHE A 1 353 ? 129.099 123.958 113.383 1.00 186.71 ?  335 PHE A CD1 1 
ATOM 2250 C CD2 . PHE A 1 353 ? 128.224 121.987 114.363 1.00 186.71 ?  335 PHE A CD2 1 
ATOM 2251 C CE1 . PHE A 1 353 ? 127.910 124.589 113.586 1.00 186.71 ?  335 PHE A CE1 1 
ATOM 2252 C CE2 . PHE A 1 353 ? 127.033 122.611 114.566 1.00 186.71 ?  335 PHE A CE2 1 
ATOM 2253 C CZ  . PHE A 1 353 ? 126.873 123.916 114.178 1.00 186.71 ?  335 PHE A CZ  1 
ATOM 2254 N N   . PHE A 1 354 ? 133.155 120.983 112.470 1.00 194.74 ?  336 PHE A N   1 
ATOM 2255 C CA  . PHE A 1 354 ? 134.601 121.117 112.421 1.00 194.74 ?  336 PHE A CA  1 
ATOM 2256 C C   . PHE A 1 354 ? 135.093 121.127 110.988 1.00 194.74 ?  336 PHE A C   1 
ATOM 2257 O O   . PHE A 1 354 ? 135.858 122.016 110.584 1.00 194.74 ?  336 PHE A O   1 
ATOM 2258 C CB  . PHE A 1 354 ? 135.249 119.993 113.213 1.00 194.74 ?  336 PHE A CB  1 
ATOM 2259 C CG  . PHE A 1 354 ? 135.142 120.182 114.680 1.00 194.74 ?  336 PHE A CG  1 
ATOM 2260 C CD1 . PHE A 1 354 ? 135.022 121.450 115.203 1.00 194.74 ?  336 PHE A CD1 1 
ATOM 2261 C CD2 . PHE A 1 354 ? 135.141 119.105 115.536 1.00 194.74 ?  336 PHE A CD2 1 
ATOM 2262 C CE1 . PHE A 1 354 ? 134.915 121.650 116.553 1.00 194.74 ?  336 PHE A CE1 1 
ATOM 2263 C CE2 . PHE A 1 354 ? 135.035 119.298 116.892 1.00 194.74 ?  336 PHE A CE2 1 
ATOM 2264 C CZ  . PHE A 1 354 ? 134.921 120.576 117.401 1.00 194.74 ?  336 PHE A CZ  1 
ATOM 2265 N N   . VAL A 1 355 ? 134.649 120.153 110.194 1.00 194.95 ?  337 VAL A N   1 
ATOM 2266 C CA  . VAL A 1 355 ? 135.191 120.066 108.845 1.00 194.95 ?  337 VAL A CA  1 
ATOM 2267 C C   . VAL A 1 355 ? 134.866 121.330 108.066 1.00 194.95 ?  337 VAL A C   1 
ATOM 2268 O O   . VAL A 1 355 ? 135.748 121.930 107.447 1.00 194.95 ?  337 VAL A O   1 
ATOM 2269 C CB  . VAL A 1 355 ? 134.706 118.797 108.122 1.00 194.95 ?  337 VAL A CB  1 
ATOM 2270 C CG1 . VAL A 1 355 ? 133.210 118.727 108.079 1.00 194.95 ?  337 VAL A CG1 1 
ATOM 2271 C CG2 . VAL A 1 355 ? 135.270 118.766 106.718 1.00 194.95 ?  337 VAL A CG2 1 
ATOM 2272 N N   . GLY A 1 356 ? 133.617 121.789 108.125 1.00 202.43 ?  338 GLY A N   1 
ATOM 2273 C CA  . GLY A 1 356 ? 133.261 122.989 107.397 1.00 202.43 ?  338 GLY A CA  1 
ATOM 2274 C C   . GLY A 1 356 ? 134.010 124.208 107.883 1.00 202.43 ?  338 GLY A C   1 
ATOM 2275 O O   . GLY A 1 356 ? 134.405 125.060 107.085 1.00 202.43 ?  338 GLY A O   1 
ATOM 2276 N N   . SER A 1 357 ? 134.227 124.305 109.190 1.00 206.61 ?  339 SER A N   1 
ATOM 2277 C CA  . SER A 1 357 ? 134.987 125.426 109.715 1.00 206.61 ?  339 SER A CA  1 
ATOM 2278 C C   . SER A 1 357 ? 136.400 125.412 109.172 1.00 206.61 ?  339 SER A C   1 
ATOM 2279 O O   . SER A 1 357 ? 137.017 126.468 109.001 1.00 206.61 ?  339 SER A O   1 
ATOM 2280 C CB  . SER A 1 357 ? 135.007 125.371 111.235 1.00 206.61 ?  339 SER A CB  1 
ATOM 2281 O OG  . SER A 1 357 ? 135.295 124.055 111.666 1.00 206.61 ?  339 SER A OG  1 
ATOM 2282 N N   . ARG A 1 358 ? 136.922 124.223 108.879 1.00 214.46 ?  340 ARG A N   1 
ATOM 2283 C CA  . ARG A 1 358 ? 138.305 124.129 108.435 1.00 214.46 ?  340 ARG A CA  1 
ATOM 2284 C C   . ARG A 1 358 ? 138.598 124.928 107.173 1.00 214.46 ?  340 ARG A C   1 
ATOM 2285 O O   . ARG A 1 358 ? 139.768 125.032 106.795 1.00 214.46 ?  340 ARG A O   1 
ATOM 2286 C CB  . ARG A 1 358 ? 138.684 122.672 108.198 1.00 214.46 ?  340 ARG A CB  1 
ATOM 2287 C CG  . ARG A 1 358 ? 138.773 121.845 109.461 1.00 214.46 ?  340 ARG A CG  1 
ATOM 2288 C CD  . ARG A 1 358 ? 139.667 120.632 109.265 1.00 214.46 ?  340 ARG A CD  1 
ATOM 2289 N NE  . ARG A 1 358 ? 139.034 119.615 108.432 1.00 214.46 ?  340 ARG A NE  1 
ATOM 2290 C CZ  . ARG A 1 358 ? 139.302 119.433 107.143 1.00 214.46 ?  340 ARG A CZ  1 
ATOM 2291 N NH1 . ARG A 1 358 ? 140.194 120.205 106.536 1.00 214.46 1  340 ARG A NH1 1 
ATOM 2292 N NH2 . ARG A 1 358 ? 138.680 118.482 106.461 1.00 214.46 ?  340 ARG A NH2 1 
ATOM 2293 N N   . GLU A 1 359 ? 137.588 125.486 106.507 1.00 219.39 ?  341 GLU A N   1 
ATOM 2294 C CA  . GLU A 1 359 ? 137.803 126.206 105.258 1.00 219.39 ?  341 GLU A CA  1 
ATOM 2295 C C   . GLU A 1 359 ? 137.065 127.536 105.213 1.00 219.39 ?  341 GLU A C   1 
ATOM 2296 O O   . GLU A 1 359 ? 136.397 127.834 104.220 1.00 219.39 ?  341 GLU A O   1 
ATOM 2297 C CB  . GLU A 1 359 ? 137.392 125.351 104.061 1.00 219.39 ?  341 GLU A CB  1 
ATOM 2298 C CG  . GLU A 1 359 ? 137.936 123.943 104.074 1.00 219.39 ?  341 GLU A CG  1 
ATOM 2299 C CD  . GLU A 1 359 ? 137.147 123.052 104.997 1.00 219.39 ?  341 GLU A CD  1 
ATOM 2300 O OE1 . GLU A 1 359 ? 136.026 123.456 105.369 1.00 219.39 ?  341 GLU A OE1 1 
ATOM 2301 O OE2 . GLU A 1 359 ? 137.642 121.965 105.354 1.00 219.39 -1 341 GLU A OE2 1 
ATOM 2302 N N   . GLY A 1 360 ? 137.153 128.336 106.271 1.00 226.36 ?  342 GLY A N   1 
ATOM 2303 C CA  . GLY A 1 360 ? 136.631 129.677 106.273 1.00 226.36 ?  342 GLY A CA  1 
ATOM 2304 C C   . GLY A 1 360 ? 135.133 129.762 106.474 1.00 226.36 ?  342 GLY A C   1 
ATOM 2305 O O   . GLY A 1 360 ? 134.648 130.746 107.041 1.00 226.36 ?  342 GLY A O   1 
ATOM 2306 N N   . HIS A 1 361 ? 134.390 128.763 106.014 1.00 215.91 ?  343 HIS A N   1 
ATOM 2307 C CA  . HIS A 1 361 ? 132.987 128.692 106.363 1.00 215.91 ?  343 HIS A CA  1 
ATOM 2308 C C   . HIS A 1 361 ? 132.848 128.599 107.873 1.00 215.91 ?  343 HIS A C   1 
ATOM 2309 O O   . HIS A 1 361 ? 133.769 128.177 108.577 1.00 215.91 ?  343 HIS A O   1 
ATOM 2310 C CB  . HIS A 1 361 ? 132.333 127.477 105.720 1.00 215.91 ?  343 HIS A CB  1 
ATOM 2311 C CG  . HIS A 1 361 ? 132.837 127.175 104.347 1.00 215.91 ?  343 HIS A CG  1 
ATOM 2312 N ND1 . HIS A 1 361 ? 134.031 126.525 104.120 1.00 215.91 ?  343 HIS A ND1 1 
ATOM 2313 C CD2 . HIS A 1 361 ? 132.301 127.413 103.127 1.00 215.91 ?  343 HIS A CD2 1 
ATOM 2314 C CE1 . HIS A 1 361 ? 134.212 126.384 102.820 1.00 215.91 ?  343 HIS A CE1 1 
ATOM 2315 N NE2 . HIS A 1 361 ? 133.177 126.915 102.195 1.00 215.91 ?  343 HIS A NE2 1 
ATOM 2316 N N   . LEU A 1 362 ? 131.671 128.981 108.369 1.00 219.90 ?  344 LEU A N   1 
ATOM 2317 C CA  . LEU A 1 362 ? 131.379 128.867 109.791 1.00 219.90 ?  344 LEU A CA  1 
ATOM 2318 C C   . LEU A 1 362 ? 132.415 129.643 110.585 1.00 219.90 ?  344 LEU A C   1 
ATOM 2319 O O   . LEU A 1 362 ? 133.315 129.027 111.169 1.00 219.90 ?  344 LEU A O   1 
ATOM 2320 C CB  . LEU A 1 362 ? 131.378 127.409 110.241 1.00 219.90 ?  344 LEU A CB  1 
ATOM 2321 C CG  . LEU A 1 362 ? 130.847 126.398 109.236 1.00 219.90 ?  344 LEU A CG  1 
ATOM 2322 C CD1 . LEU A 1 362 ? 131.055 124.998 109.766 1.00 219.90 ?  344 LEU A CD1 1 
ATOM 2323 C CD2 . LEU A 1 362 ? 129.388 126.672 108.953 1.00 219.90 ?  344 LEU A CD2 1 
ATOM 2324 N N   . PRO A 1 363 ? 132.350 130.976 110.590 1.00 219.79 ?  345 PRO A N   1 
ATOM 2325 C CA  . PRO A 1 363 ? 133.422 131.784 111.184 1.00 219.79 ?  345 PRO A CA  1 
ATOM 2326 C C   . PRO A 1 363 ? 134.006 131.204 112.458 1.00 219.79 ?  345 PRO A C   1 
ATOM 2327 O O   . PRO A 1 363 ? 133.293 130.730 113.347 1.00 219.79 ?  345 PRO A O   1 
ATOM 2328 C CB  . PRO A 1 363 ? 132.728 133.122 111.438 1.00 219.79 ?  345 PRO A CB  1 
ATOM 2329 C CG  . PRO A 1 363 ? 131.769 133.224 110.302 1.00 219.79 ?  345 PRO A CG  1 
ATOM 2330 C CD  . PRO A 1 363 ? 131.281 131.818 110.030 1.00 219.79 ?  345 PRO A CD  1 
ATOM 2331 N N   . ASP A 1 364 ? 135.333 131.257 112.529 1.00 217.51 ?  346 ASP A N   1 
ATOM 2332 C CA  . ASP A 1 364 ? 136.134 130.431 113.420 1.00 217.51 ?  346 ASP A CA  1 
ATOM 2333 C C   . ASP A 1 364 ? 135.753 130.547 114.885 1.00 217.51 ?  346 ASP A C   1 
ATOM 2334 O O   . ASP A 1 364 ? 136.274 129.776 115.696 1.00 217.51 ?  346 ASP A O   1 
ATOM 2335 C CB  . ASP A 1 364 ? 137.596 130.805 113.234 1.00 217.51 ?  346 ASP A CB  1 
ATOM 2336 C CG  . ASP A 1 364 ? 137.777 132.287 113.010 1.00 217.51 ?  346 ASP A CG  1 
ATOM 2337 O OD1 . ASP A 1 364 ? 136.753 132.996 112.938 1.00 217.51 ?  346 ASP A OD1 1 
ATOM 2338 O OD2 . ASP A 1 364 ? 138.933 132.743 112.894 1.00 217.51 -1 346 ASP A OD2 1 
ATOM 2339 N N   . ALA A 1 365 ? 134.894 131.493 115.254 1.00 226.05 ?  347 ALA A N   1 
ATOM 2340 C CA  . ALA A 1 365 ? 134.408 131.534 116.627 1.00 226.05 ?  347 ALA A CA  1 
ATOM 2341 C C   . ALA A 1 365 ? 133.771 130.207 117.009 1.00 226.05 ?  347 ALA A C   1 
ATOM 2342 O O   . ALA A 1 365 ? 134.035 129.659 118.085 1.00 226.05 ?  347 ALA A O   1 
ATOM 2343 C CB  . ALA A 1 365 ? 133.417 132.681 116.798 1.00 226.05 ?  347 ALA A CB  1 
ATOM 2344 N N   . ILE A 1 366 ? 132.948 129.664 116.122 1.00 200.73 ?  348 ILE A N   1 
ATOM 2345 C CA  . ILE A 1 366 ? 132.364 128.347 116.309 1.00 200.73 ?  348 ILE A CA  1 
ATOM 2346 C C   . ILE A 1 366 ? 133.495 127.336 116.292 1.00 200.73 ?  348 ILE A C   1 
ATOM 2347 O O   . ILE A 1 366 ? 134.629 127.669 115.935 1.00 200.73 ?  348 ILE A O   1 
ATOM 2348 C CB  . ILE A 1 366 ? 131.329 128.041 115.216 1.00 200.73 ?  348 ILE A CB  1 
ATOM 2349 C CG1 . ILE A 1 366 ? 130.451 126.856 115.612 1.00 200.73 ?  348 ILE A CG1 1 
ATOM 2350 C CG2 . ILE A 1 366 ? 132.035 127.754 113.912 1.00 200.73 ?  348 ILE A CG2 1 
ATOM 2351 C CD1 . ILE A 1 366 ? 129.761 127.036 116.932 1.00 200.73 ?  348 ILE A CD1 1 
ATOM 2352 N N   . CYS A 1 367 ? 133.200 126.103 116.687 1.00 206.53 ?  349 CYS A N   1 
ATOM 2353 C CA  . CYS A 1 367 ? 134.155 125.007 116.620 1.00 206.53 ?  349 CYS A CA  1 
ATOM 2354 C C   . CYS A 1 367 ? 135.339 125.259 117.550 1.00 206.53 ?  349 CYS A C   1 
ATOM 2355 O O   . CYS A 1 367 ? 136.491 125.353 117.130 1.00 206.53 ?  349 CYS A O   1 
ATOM 2356 C CB  . CYS A 1 367 ? 134.621 124.798 115.179 1.00 206.53 ?  349 CYS A CB  1 
ATOM 2357 S SG  . CYS A 1 367 ? 133.356 124.122 114.105 1.00 206.53 ?  349 CYS A SG  1 
ATOM 2358 N N   . MET A 1 368 ? 135.039 125.358 118.840 1.00 215.77 ?  350 MET A N   1 
ATOM 2359 C CA  . MET A 1 368 ? 136.089 125.576 119.824 1.00 215.77 ?  350 MET A CA  1 
ATOM 2360 C C   . MET A 1 368 ? 136.023 124.495 120.889 1.00 215.77 ?  350 MET A C   1 
ATOM 2361 O O   . MET A 1 368 ? 134.990 124.318 121.536 1.00 215.77 ?  350 MET A O   1 
ATOM 2362 C CB  . MET A 1 368 ? 135.935 126.950 120.467 1.00 215.77 ?  350 MET A CB  1 
ATOM 2363 C CG  . MET A 1 368 ? 136.474 128.096 119.632 1.00 215.77 ?  350 MET A CG  1 
ATOM 2364 S SD  . MET A 1 368 ? 136.520 129.635 120.571 1.00 215.77 ?  350 MET A SD  1 
ATOM 2365 C CE  . MET A 1 368 ? 138.097 130.304 120.052 1.00 215.77 ?  350 MET A CE  1 
ATOM 2366 N N   . ILE A 1 369 ? 137.117 123.769 121.073 1.00 208.61 ?  351 ILE A N   1 
ATOM 2367 C CA  . ILE A 1 369 ? 137.153 122.717 122.082 1.00 208.61 ?  351 ILE A CA  1 
ATOM 2368 C C   . ILE A 1 369 ? 137.195 123.324 123.480 1.00 208.61 ?  351 ILE A C   1 
ATOM 2369 O O   . ILE A 1 369 ? 137.848 124.341 123.707 1.00 208.61 ?  351 ILE A O   1 
ATOM 2370 C CB  . ILE A 1 369 ? 138.351 121.772 121.853 1.00 208.61 ?  351 ILE A CB  1 
ATOM 2371 C CG1 . ILE A 1 369 ? 137.851 120.353 121.582 1.00 208.61 ?  351 ILE A CG1 1 
ATOM 2372 C CG2 . ILE A 1 369 ? 139.313 121.796 123.033 1.00 208.61 ?  351 ILE A CG2 1 
ATOM 2373 C CD1 . ILE A 1 369 ? 136.469 120.303 120.971 1.00 208.61 ?  351 ILE A CD1 1 
ATOM 2374 N N   . HIS A 1 370 ? 136.484 122.719 124.421 1.00 216.20 ?  352 HIS A N   1 
ATOM 2375 C CA  . HIS A 1 370 ? 136.432 123.303 125.753 1.00 216.20 ?  352 HIS A CA  1 
ATOM 2376 C C   . HIS A 1 370 ? 137.825 123.425 126.338 1.00 216.20 ?  352 HIS A C   1 
ATOM 2377 O O   . HIS A 1 370 ? 138.639 122.511 126.212 1.00 216.20 ?  352 HIS A O   1 
ATOM 2378 C CB  . HIS A 1 370 ? 135.547 122.496 126.689 1.00 216.20 ?  352 HIS A CB  1 
ATOM 2379 C CG  . HIS A 1 370 ? 135.254 123.198 127.976 1.00 216.20 ?  352 HIS A CG  1 
ATOM 2380 N ND1 . HIS A 1 370 ? 136.139 123.213 129.032 1.00 216.20 ?  352 HIS A ND1 1 
ATOM 2381 C CD2 . HIS A 1 370 ? 134.186 123.930 128.369 1.00 216.20 ?  352 HIS A CD2 1 
ATOM 2382 C CE1 . HIS A 1 370 ? 135.622 123.913 130.025 1.00 216.20 ?  352 HIS A CE1 1 
ATOM 2383 N NE2 . HIS A 1 370 ? 134.438 124.359 129.649 1.00 216.20 ?  352 HIS A NE2 1 
ATOM 2384 N N   . VAL A 1 371 ? 138.097 124.549 126.989 1.00 217.42 ?  353 VAL A N   1 
ATOM 2385 C CA  . VAL A 1 371 ? 139.424 124.782 127.552 1.00 217.42 ?  353 VAL A CA  1 
ATOM 2386 C C   . VAL A 1 371 ? 139.985 123.552 128.268 1.00 217.42 ?  353 VAL A C   1 
ATOM 2387 O O   . VAL A 1 371 ? 141.181 123.279 128.184 1.00 217.42 ?  353 VAL A O   1 
ATOM 2388 C CB  . VAL A 1 371 ? 139.419 125.993 128.512 1.00 217.42 ?  353 VAL A CB  1 
ATOM 2389 C CG1 . VAL A 1 371 ? 138.647 125.685 129.786 1.00 217.42 ?  353 VAL A CG1 1 
ATOM 2390 C CG2 . VAL A 1 371 ? 140.841 126.426 128.829 1.00 217.42 ?  353 VAL A CG2 1 
ATOM 2391 N N   . GLU A 1 372 ? 139.132 122.805 128.959 1.00 223.25 ?  354 GLU A N   1 
ATOM 2392 C CA  . GLU A 1 372 ? 139.600 121.644 129.703 1.00 223.25 ?  354 GLU A CA  1 
ATOM 2393 C C   . GLU A 1 372 ? 138.768 120.417 129.383 1.00 223.25 ?  354 GLU A C   1 
ATOM 2394 O O   . GLU A 1 372 ? 139.259 119.293 129.446 1.00 223.25 ?  354 GLU A O   1 
ATOM 2395 C CB  . GLU A 1 372 ? 139.559 121.926 131.203 1.00 223.25 ?  354 GLU A CB  1 
ATOM 2396 C CG  . GLU A 1 372 ? 138.216 122.428 131.698 1.00 223.25 ?  354 GLU A CG  1 
ATOM 2397 C CD  . GLU A 1 372 ? 137.296 121.300 132.115 1.00 223.25 ?  354 GLU A CD  1 
ATOM 2398 O OE1 . GLU A 1 372 ? 136.191 121.188 131.544 1.00 223.25 ?  354 GLU A OE1 1 
ATOM 2399 O OE2 . GLU A 1 372 ? 137.683 120.522 133.010 1.00 223.25 -1 354 GLU A OE2 1 
ATOM 2400 N N   . ARG A 1 373 ? 137.503 120.628 129.047 1.00 217.42 ?  355 ARG A N   1 
ATOM 2401 C CA  . ARG A 1 373 ? 136.641 119.513 128.703 1.00 217.42 ?  355 ARG A CA  1 
ATOM 2402 C C   . ARG A 1 373 ? 136.973 119.028 127.306 1.00 217.42 ?  355 ARG A C   1 
ATOM 2403 O O   . ARG A 1 373 ? 136.573 117.931 126.918 1.00 217.42 ?  355 ARG A O   1 
ATOM 2404 C CB  . ARG A 1 373 ? 135.172 119.915 128.797 1.00 217.42 ?  355 ARG A CB  1 
ATOM 2405 C CG  . ARG A 1 373 ? 134.280 118.897 129.484 1.00 217.42 ?  355 ARG A CG  1 
ATOM 2406 C CD  . ARG A 1 373 ? 135.081 117.724 130.020 1.00 217.42 ?  355 ARG A CD  1 
ATOM 2407 N NE  . ARG A 1 373 ? 135.226 117.795 131.469 1.00 217.42 ?  355 ARG A NE  1 
ATOM 2408 C CZ  . ARG A 1 373 ? 136.387 117.946 132.096 1.00 217.42 ?  355 ARG A CZ  1 
ATOM 2409 N NH1 . ARG A 1 373 ? 137.513 118.043 131.404 1.00 217.42 1  355 ARG A NH1 1 
ATOM 2410 N NH2 . ARG A 1 373 ? 136.423 118.001 133.419 1.00 217.42 ?  355 ARG A NH2 1 
ATOM 2411 N N   . PHE A 1 374 ? 137.715 119.836 126.554 1.00 210.79 ?  356 PHE A N   1 
ATOM 2412 C CA  . PHE A 1 374 ? 138.075 119.460 125.194 1.00 210.79 ?  356 PHE A CA  1 
ATOM 2413 C C   . PHE A 1 374 ? 136.808 119.011 124.513 1.00 210.79 ?  356 PHE A C   1 
ATOM 2414 O O   . PHE A 1 374 ? 136.828 118.141 123.645 1.00 210.79 ?  356 PHE A O   1 
ATOM 2415 C CB  . PHE A 1 374 ? 139.146 118.380 125.215 1.00 210.79 ?  356 PHE A CB  1 
ATOM 2416 C CG  . PHE A 1 374 ? 140.211 118.629 126.238 1.00 210.79 ?  356 PHE A CG  1 
ATOM 2417 C CD1 . PHE A 1 374 ? 140.765 119.891 126.378 1.00 210.79 ?  356 PHE A CD1 1 
ATOM 2418 C CD2 . PHE A 1 374 ? 140.644 117.616 127.072 1.00 210.79 ?  356 PHE A CD2 1 
ATOM 2419 C CE1 . PHE A 1 374 ? 141.740 120.135 127.323 1.00 210.79 ?  356 PHE A CE1 1 
ATOM 2420 C CE2 . PHE A 1 374 ? 141.622 117.852 128.019 1.00 210.79 ?  356 PHE A CE2 1 
ATOM 2421 C CZ  . PHE A 1 374 ? 142.170 119.114 128.145 1.00 210.79 ?  356 PHE A CZ  1 
ATOM 2422 N N   . THR A 1 375 ? 135.698 119.603 124.918 1.00 200.26 ?  357 THR A N   1 
ATOM 2423 C CA  . THR A 1 375 ? 134.407 119.282 124.340 1.00 200.26 ?  357 THR A CA  1 
ATOM 2424 C C   . THR A 1 375 ? 134.009 120.365 123.359 1.00 200.26 ?  357 THR A C   1 
ATOM 2425 O O   . THR A 1 375 ? 134.363 121.533 123.549 1.00 200.26 ?  357 THR A O   1 
ATOM 2426 C CB  . THR A 1 375 ? 133.330 119.150 125.422 1.00 200.26 ?  357 THR A CB  1 
ATOM 2427 O OG1 . THR A 1 375 ? 133.386 120.297 126.273 1.00 200.26 ?  357 THR A OG1 1 
ATOM 2428 C CG2 . THR A 1 375 ? 133.494 117.876 126.241 1.00 200.26 ?  357 THR A CG2 1 
ATOM 2429 N N   . PRO A 1 376 ? 133.263 120.017 122.319 1.00 191.65 ?  358 PRO A N   1 
ATOM 2430 C CA  . PRO A 1 376 ? 132.813 120.973 121.292 1.00 191.65 ?  358 PRO A CA  1 
ATOM 2431 C C   . PRO A 1 376 ? 131.508 121.652 121.688 1.00 191.65 ?  358 PRO A C   1 
ATOM 2432 O O   . PRO A 1 376 ? 130.487 121.573 121.000 1.00 191.65 ?  358 PRO A O   1 
ATOM 2433 C CB  . PRO A 1 376 ? 132.643 120.072 120.073 1.00 191.65 ?  358 PRO A CB  1 
ATOM 2434 C CG  . PRO A 1 376 ? 132.152 118.802 120.667 1.00 191.65 ?  358 PRO A CG  1 
ATOM 2435 C CD  . PRO A 1 376 ? 132.849 118.644 121.992 1.00 191.65 ?  358 PRO A CD  1 
ATOM 2436 N N   . VAL A 1 377 ? 131.549 122.341 122.819 1.00 183.92 ?  359 VAL A N   1 
ATOM 2437 C CA  . VAL A 1 377 ? 130.348 122.870 123.450 1.00 183.92 ?  359 VAL A CA  1 
ATOM 2438 C C   . VAL A 1 377 ? 129.524 123.702 122.475 1.00 183.92 ?  359 VAL A C   1 
ATOM 2439 O O   . VAL A 1 377 ? 128.416 123.284 122.106 1.00 183.92 ?  359 VAL A O   1 
ATOM 2440 C CB  . VAL A 1 377 ? 130.709 123.683 124.699 1.00 183.92 ?  359 VAL A CB  1 
ATOM 2441 C CG1 . VAL A 1 377 ? 129.471 123.994 125.489 1.00 183.92 ?  359 VAL A CG1 1 
ATOM 2442 C CG2 . VAL A 1 377 ? 131.690 122.909 125.539 1.00 183.92 ?  359 VAL A CG2 1 
ATOM 2443 N N   . PRO A 1 378 ? 130.018 124.845 122.000 1.00 166.61 ?  360 PRO A N   1 
ATOM 2444 C CA  . PRO A 1 378 ? 129.120 125.780 121.315 1.00 166.61 ?  360 PRO A CA  1 
ATOM 2445 C C   . PRO A 1 378 ? 128.434 125.171 120.119 1.00 166.61 ?  360 PRO A C   1 
ATOM 2446 O O   . PRO A 1 378 ? 127.282 125.517 119.830 1.00 166.61 ?  360 PRO A O   1 
ATOM 2447 C CB  . PRO A 1 378 ? 130.054 126.924 120.909 1.00 166.61 ?  360 PRO A CB  1 
ATOM 2448 C CG  . PRO A 1 378 ? 131.281 126.718 121.711 1.00 166.61 ?  360 PRO A CG  1 
ATOM 2449 C CD  . PRO A 1 378 ? 131.414 125.259 121.838 1.00 166.61 ?  360 PRO A CD  1 
ATOM 2450 N N   . SER A 1 379 ? 129.108 124.269 119.415 1.00 182.83 ?  361 SER A N   1 
ATOM 2451 C CA  . SER A 1 379 ? 128.451 123.514 118.361 1.00 182.83 ?  361 SER A CA  1 
ATOM 2452 C C   . SER A 1 379 ? 127.189 122.854 118.885 1.00 182.83 ?  361 SER A C   1 
ATOM 2453 O O   . SER A 1 379 ? 126.091 123.058 118.353 1.00 182.83 ?  361 SER A O   1 
ATOM 2454 C CB  . SER A 1 379 ? 129.404 122.459 117.821 1.00 182.83 ?  361 SER A CB  1 
ATOM 2455 O OG  . SER A 1 379 ? 129.787 121.593 118.874 1.00 182.83 ?  361 SER A OG  1 
ATOM 2456 N N   . LEU A 1 380 ? 127.342 122.030 119.918 1.00 172.47 ?  362 LEU A N   1 
ATOM 2457 C CA  . LEU A 1 380 ? 126.196 121.339 120.483 1.00 172.47 ?  362 LEU A CA  1 
ATOM 2458 C C   . LEU A 1 380 ? 125.124 122.322 120.895 1.00 172.47 ?  362 LEU A C   1 
ATOM 2459 O O   . LEU A 1 380 ? 123.942 122.113 120.621 1.00 172.47 ?  362 LEU A O   1 
ATOM 2460 C CB  . LEU A 1 380 ? 126.623 120.511 121.683 1.00 172.47 ?  362 LEU A CB  1 
ATOM 2461 C CG  . LEU A 1 380 ? 127.210 119.135 121.419 1.00 172.47 ?  362 LEU A CG  1 
ATOM 2462 C CD1 . LEU A 1 380 ? 128.499 119.231 120.639 1.00 172.47 ?  362 LEU A CD1 1 
ATOM 2463 C CD2 . LEU A 1 380 ? 127.432 118.421 122.743 1.00 172.47 ?  362 LEU A CD2 1 
ATOM 2464 N N   . LEU A 1 381 ? 125.522 123.390 121.573 1.00 147.06 ?  363 LEU A N   1 
ATOM 2465 C CA  . LEU A 1 381 ? 124.558 124.389 122.001 1.00 147.06 ?  363 LEU A CA  1 
ATOM 2466 C C   . LEU A 1 381 ? 123.718 124.871 120.835 1.00 147.06 ?  363 LEU A C   1 
ATOM 2467 O O   . LEU A 1 381 ? 122.481 124.811 120.866 1.00 147.06 ?  363 LEU A O   1 
ATOM 2468 C CB  . LEU A 1 381 ? 125.294 125.551 122.648 1.00 147.06 ?  363 LEU A CB  1 
ATOM 2469 C CG  . LEU A 1 381 ? 124.445 126.708 123.139 1.00 147.06 ?  363 LEU A CG  1 
ATOM 2470 C CD1 . LEU A 1 381 ? 125.074 127.284 124.374 1.00 147.06 ?  363 LEU A CD1 1 
ATOM 2471 C CD2 . LEU A 1 381 ? 124.369 127.770 122.062 1.00 147.06 ?  363 LEU A CD2 1 
ATOM 2472 N N   . PHE A 1 382 ? 124.377 125.374 119.804 1.00 153.06 ?  364 PHE A N   1 
ATOM 2473 C CA  . PHE A 1 382 ? 123.644 125.950 118.695 1.00 153.06 ?  364 PHE A CA  1 
ATOM 2474 C C   . PHE A 1 382 ? 122.745 124.919 118.044 1.00 153.06 ?  364 PHE A C   1 
ATOM 2475 O O   . PHE A 1 382 ? 121.577 125.200 117.748 1.00 153.06 ?  364 PHE A O   1 
ATOM 2476 C CB  . PHE A 1 382 ? 124.620 126.523 117.682 1.00 153.06 ?  364 PHE A CB  1 
ATOM 2477 C CG  . PHE A 1 382 ? 123.973 126.995 116.436 1.00 153.06 ?  364 PHE A CG  1 
ATOM 2478 C CD1 . PHE A 1 382 ? 123.573 128.302 116.313 1.00 153.06 ?  364 PHE A CD1 1 
ATOM 2479 C CD2 . PHE A 1 382 ? 123.769 126.136 115.381 1.00 153.06 ?  364 PHE A CD2 1 
ATOM 2480 C CE1 . PHE A 1 382 ? 122.980 128.742 115.166 1.00 153.06 ?  364 PHE A CE1 1 
ATOM 2481 C CE2 . PHE A 1 382 ? 123.176 126.572 114.237 1.00 153.06 ?  364 PHE A CE2 1 
ATOM 2482 C CZ  . PHE A 1 382 ? 122.782 127.877 114.126 1.00 153.06 ?  364 PHE A CZ  1 
ATOM 2483 N N   . ASN A 1 383 ? 123.272 123.724 117.797 1.00 147.78 ?  365 ASN A N   1 
ATOM 2484 C CA  . ASN A 1 383 ? 122.461 122.720 117.128 1.00 147.78 ?  365 ASN A CA  1 
ATOM 2485 C C   . ASN A 1 383 ? 121.247 122.371 117.957 1.00 147.78 ?  365 ASN A C   1 
ATOM 2486 O O   . ASN A 1 383 ? 120.145 122.204 117.426 1.00 147.78 ?  365 ASN A O   1 
ATOM 2487 C CB  . ASN A 1 383 ? 123.264 121.462 116.865 1.00 147.78 ?  365 ASN A CB  1 
ATOM 2488 C CG  . ASN A 1 383 ? 122.384 120.313 116.488 1.00 147.78 ?  365 ASN A CG  1 
ATOM 2489 O OD1 . ASN A 1 383 ? 121.547 120.431 115.605 1.00 147.78 ?  365 ASN A OD1 1 
ATOM 2490 N ND2 . ASN A 1 383 ? 122.534 119.204 117.180 1.00 147.78 ?  365 ASN A ND2 1 
ATOM 2491 N N   . GLY A 1 384 ? 121.430 122.246 119.263 1.00 140.08 ?  366 GLY A N   1 
ATOM 2492 C CA  . GLY A 1 384 ? 120.311 121.919 120.116 1.00 140.08 ?  366 GLY A CA  1 
ATOM 2493 C C   . GLY A 1 384 ? 119.233 122.974 120.059 1.00 140.08 ?  366 GLY A C   1 
ATOM 2494 O O   . GLY A 1 384 ? 118.051 122.658 119.963 1.00 140.08 ?  366 GLY A O   1 
ATOM 2495 N N   . ILE A 1 385 ? 119.625 124.240 120.105 1.00 132.59 ?  367 ILE A N   1 
ATOM 2496 C CA  . ILE A 1 385 ? 118.622 125.294 120.051 1.00 132.59 ?  367 ILE A CA  1 
ATOM 2497 C C   . ILE A 1 385 ? 117.876 125.244 118.727 1.00 132.59 ?  367 ILE A C   1 
ATOM 2498 O O   . ILE A 1 385 ? 116.641 125.347 118.676 1.00 132.59 ?  367 ILE A O   1 
ATOM 2499 C CB  . ILE A 1 385 ? 119.273 126.662 120.281 1.00 132.59 ?  367 ILE A CB  1 
ATOM 2500 C CG1 . ILE A 1 385 ? 119.484 126.876 121.771 1.00 132.59 ?  367 ILE A CG1 1 
ATOM 2501 C CG2 . ILE A 1 385 ? 118.421 127.753 119.699 1.00 132.59 ?  367 ILE A CG2 1 
ATOM 2502 C CD1 . ILE A 1 385 ? 120.195 128.149 122.089 1.00 132.59 ?  367 ILE A CD1 1 
ATOM 2503 N N   . MET A 1 386 ? 118.613 125.039 117.642 1.00 160.39 ?  368 MET A N   1 
ATOM 2504 C CA  . MET A 1 386 ? 117.978 124.924 116.335 1.00 160.39 ?  368 MET A CA  1 
ATOM 2505 C C   . MET A 1 386 ? 116.976 123.781 116.316 1.00 160.39 ?  368 MET A C   1 
ATOM 2506 O O   . MET A 1 386 ? 115.801 123.985 116.020 1.00 160.39 ?  368 MET A O   1 
ATOM 2507 C CB  . MET A 1 386 ? 119.030 124.706 115.249 1.00 160.39 ?  368 MET A CB  1 
ATOM 2508 C CG  . MET A 1 386 ? 119.975 125.879 115.062 1.00 160.39 ?  368 MET A CG  1 
ATOM 2509 S SD  . MET A 1 386 ? 119.184 127.462 115.402 1.00 160.39 ?  368 MET A SD  1 
ATOM 2510 C CE  . MET A 1 386 ? 120.156 128.034 116.793 1.00 160.39 ?  368 MET A CE  1 
ATOM 2511 N N   . ALA A 1 387 ? 117.433 122.576 116.637 1.00 154.58 ?  369 ALA A N   1 
ATOM 2512 C CA  . ALA A 1 387 ? 116.555 121.409 116.606 1.00 154.58 ?  369 ALA A CA  1 
ATOM 2513 C C   . ALA A 1 387 ? 115.392 121.532 117.582 1.00 154.58 ?  369 ALA A C   1 
ATOM 2514 O O   . ALA A 1 387 ? 114.288 121.071 117.295 1.00 154.58 ?  369 ALA A O   1 
ATOM 2515 C CB  . ALA A 1 387 ? 117.352 120.146 116.895 1.00 154.58 ?  369 ALA A CB  1 
ATOM 2516 N N   . LEU A 1 388 ? 115.632 122.150 118.732 1.00 141.33 ?  370 LEU A N   1 
ATOM 2517 C CA  . LEU A 1 388 ? 114.587 122.252 119.748 1.00 141.33 ?  370 LEU A CA  1 
ATOM 2518 C C   . LEU A 1 388 ? 113.337 122.943 119.218 1.00 141.33 ?  370 LEU A C   1 
ATOM 2519 O O   . LEU A 1 388 ? 112.220 122.493 119.472 1.00 141.33 ?  370 LEU A O   1 
ATOM 2520 C CB  . LEU A 1 388 ? 115.110 122.993 120.979 1.00 141.33 ?  370 LEU A CB  1 
ATOM 2521 C CG  . LEU A 1 388 ? 115.283 122.128 122.227 1.00 141.33 ?  370 LEU A CG  1 
ATOM 2522 C CD1 . LEU A 1 388 ? 116.574 122.471 122.953 1.00 141.33 ?  370 LEU A CD1 1 
ATOM 2523 C CD2 . LEU A 1 388 ? 114.084 122.272 123.152 1.00 141.33 ?  370 LEU A CD2 1 
ATOM 2524 N N   . ILE A 1 389 ? 113.521 124.030 118.478 1.00 140.79 ?  371 ILE A N   1 
ATOM 2525 C CA  . ILE A 1 389 ? 112.380 124.759 117.937 1.00 140.79 ?  371 ILE A CA  1 
ATOM 2526 C C   . ILE A 1 389 ? 111.567 123.859 117.018 1.00 140.79 ?  371 ILE A C   1 
ATOM 2527 O O   . ILE A 1 389 ? 110.345 123.985 116.941 1.00 140.79 ?  371 ILE A O   1 
ATOM 2528 C CB  . ILE A 1 389 ? 112.820 126.028 117.179 1.00 140.79 ?  371 ILE A CB  1 
ATOM 2529 C CG1 . ILE A 1 389 ? 113.355 125.678 115.789 1.00 140.79 ?  371 ILE A CG1 1 
ATOM 2530 C CG2 . ILE A 1 389 ? 113.873 126.783 117.976 1.00 140.79 ?  371 ILE A CG2 1 
ATOM 2531 C CD1 . ILE A 1 389 ? 112.422 126.050 114.659 1.00 140.79 ?  371 ILE A CD1 1 
ATOM 2532 N N   . TYR A 1 390 ? 112.240 122.949 116.325 1.00 168.03 ?  372 TYR A N   1 
ATOM 2533 C CA  . TYR A 1 390 ? 111.552 122.054 115.401 1.00 168.03 ?  372 TYR A CA  1 
ATOM 2534 C C   . TYR A 1 390 ? 110.581 121.131 116.122 1.00 168.03 ?  372 TYR A C   1 
ATOM 2535 O O   . TYR A 1 390 ? 109.544 120.763 115.570 1.00 168.03 ?  372 TYR A O   1 
ATOM 2536 C CB  . TYR A 1 390 ? 112.570 121.231 114.615 1.00 168.03 ?  372 TYR A CB  1 
ATOM 2537 C CG  . TYR A 1 390 ? 113.167 121.962 113.443 1.00 168.03 ?  372 TYR A CG  1 
ATOM 2538 C CD1 . TYR A 1 390 ? 114.098 122.971 113.634 1.00 168.03 ?  372 TYR A CD1 1 
ATOM 2539 C CD2 . TYR A 1 390 ? 112.797 121.646 112.146 1.00 168.03 ?  372 TYR A CD2 1 
ATOM 2540 C CE1 . TYR A 1 390 ? 114.646 123.646 112.562 1.00 168.03 ?  372 TYR A CE1 1 
ATOM 2541 C CE2 . TYR A 1 390 ? 113.340 122.312 111.067 1.00 168.03 ?  372 TYR A CE2 1 
ATOM 2542 C CZ  . TYR A 1 390 ? 114.263 123.311 111.282 1.00 168.03 ?  372 TYR A CZ  1 
ATOM 2543 O OH  . TYR A 1 390 ? 114.800 123.977 110.210 1.00 168.03 ?  372 TYR A OH  1 
ATOM 2544 N N   . LEU A 1 391 ? 110.909 120.757 117.354 1.00 164.16 ?  373 LEU A N   1 
ATOM 2545 C CA  . LEU A 1 391 ? 110.056 119.841 118.105 1.00 164.16 ?  373 LEU A CA  1 
ATOM 2546 C C   . LEU A 1 391 ? 108.638 120.377 118.212 1.00 164.16 ?  373 LEU A C   1 
ATOM 2547 O O   . LEU A 1 391 ? 107.674 119.615 118.140 1.00 164.16 ?  373 LEU A O   1 
ATOM 2548 C CB  . LEU A 1 391 ? 110.627 119.602 119.501 1.00 164.16 ?  373 LEU A CB  1 
ATOM 2549 C CG  . LEU A 1 391 ? 111.928 118.803 119.560 1.00 164.16 ?  373 LEU A CG  1 
ATOM 2550 C CD1 . LEU A 1 391 ? 112.859 119.393 120.604 1.00 164.16 ?  373 LEU A CD1 1 
ATOM 2551 C CD2 . LEU A 1 391 ? 111.642 117.340 119.860 1.00 164.16 ?  373 LEU A CD2 1 
ATOM 2552 N N   . CYS A 1 392 ? 108.505 121.687 118.379 1.00 166.81 ?  374 CYS A N   1 
ATOM 2553 C CA  . CYS A 1 392 ? 107.184 122.290 118.485 1.00 166.81 ?  374 CYS A CA  1 
ATOM 2554 C C   . CYS A 1 392 ? 106.563 122.424 117.106 1.00 166.81 ?  374 CYS A C   1 
ATOM 2555 O O   . CYS A 1 392 ? 106.683 123.468 116.465 1.00 166.81 ?  374 CYS A O   1 
ATOM 2556 C CB  . CYS A 1 392 ? 107.275 123.656 119.163 1.00 166.81 ?  374 CYS A CB  1 
ATOM 2557 S SG  . CYS A 1 392 ? 108.912 124.042 119.826 1.00 166.81 ?  374 CYS A SG  1 
ATOM 2558 N N   . VAL A 1 393 ? 105.902 121.368 116.645 1.00 170.96 ?  375 VAL A N   1 
ATOM 2559 C CA  . VAL A 1 393 ? 105.290 121.392 115.320 1.00 170.96 ?  375 VAL A CA  1 
ATOM 2560 C C   . VAL A 1 393 ? 103.889 120.800 115.343 1.00 170.96 ?  375 VAL A C   1 
ATOM 2561 O O   . VAL A 1 393 ? 103.531 120.073 116.270 1.00 170.96 ?  375 VAL A O   1 
ATOM 2562 C CB  . VAL A 1 393 ? 106.142 120.622 114.294 1.00 170.96 ?  375 VAL A CB  1 
ATOM 2563 C CG1 . VAL A 1 393 ? 105.840 119.133 114.360 1.00 170.96 ?  375 VAL A CG1 1 
ATOM 2564 C CG2 . VAL A 1 393 ? 105.896 121.160 112.893 1.00 170.96 ?  375 VAL A CG2 1 
ATOM 2565 N N   . GLU A 1 394 ? 103.116 121.039 114.292 1.00 174.77 ?  376 GLU A N   1 
ATOM 2566 C CA  . GLU A 1 394 ? 101.797 120.430 114.211 1.00 174.77 ?  376 GLU A CA  1 
ATOM 2567 C C   . GLU A 1 394 ? 101.902 118.916 114.053 1.00 174.77 ?  376 GLU A C   1 
ATOM 2568 O O   . GLU A 1 394 ? 101.186 118.174 114.723 1.00 174.77 ?  376 GLU A O   1 
ATOM 2569 C CB  . GLU A 1 394 ? 100.999 121.035 113.059 1.00 174.77 ?  376 GLU A CB  1 
ATOM 2570 C CG  . GLU A 1 394 ? 100.436 122.412 113.367 1.00 174.77 ?  376 GLU A CG  1 
ATOM 2571 C CD  . GLU A 1 394 ? 100.532 122.765 114.839 1.00 174.77 ?  376 GLU A CD  1 
ATOM 2572 O OE1 . GLU A 1 394 ? 99.632  122.366 115.609 1.00 174.77 ?  376 GLU A OE1 1 
ATOM 2573 O OE2 . GLU A 1 394 ? 101.509 123.440 115.229 1.00 174.77 -1 376 GLU A OE2 1 
ATOM 2574 N N   . ASP A 1 395 ? 102.794 118.455 113.178 1.00 174.21 ?  377 ASP A N   1 
ATOM 2575 C CA  . ASP A 1 395 ? 102.938 117.016 112.943 1.00 174.21 ?  377 ASP A CA  1 
ATOM 2576 C C   . ASP A 1 395 ? 104.287 116.614 112.353 1.00 174.21 ?  377 ASP A C   1 
ATOM 2577 O O   . ASP A 1 395 ? 104.901 117.376 111.605 1.00 174.21 ?  377 ASP A O   1 
ATOM 2578 C CB  . ASP A 1 395 ? 101.807 116.513 112.037 1.00 174.21 ?  377 ASP A CB  1 
ATOM 2579 C CG  . ASP A 1 395 ? 102.288 115.524 110.996 1.00 174.21 ?  377 ASP A CG  1 
ATOM 2580 O OD1 . ASP A 1 395 ? 102.470 114.336 111.338 1.00 174.21 ?  377 ASP A OD1 1 
ATOM 2581 O OD2 . ASP A 1 395 ? 102.488 115.934 109.836 1.00 174.21 -1 377 ASP A OD2 1 
ATOM 2582 N N   . ILE A 1 396 ? 104.743 115.409 112.682 1.00 173.65 ?  378 ILE A N   1 
ATOM 2583 C CA  . ILE A 1 396 ? 106.014 114.922 112.158 1.00 173.65 ?  378 ILE A CA  1 
ATOM 2584 C C   . ILE A 1 396 ? 105.982 114.746 110.652 1.00 173.65 ?  378 ILE A C   1 
ATOM 2585 O O   . ILE A 1 396 ? 106.894 115.177 109.960 1.00 173.65 ?  378 ILE A O   1 
ATOM 2586 C CB  . ILE A 1 396 ? 106.388 113.567 112.778 1.00 173.65 ?  378 ILE A CB  1 
ATOM 2587 C CG1 . ILE A 1 396 ? 106.478 113.686 114.299 1.00 173.65 ?  378 ILE A CG1 1 
ATOM 2588 C CG2 . ILE A 1 396 ? 107.698 113.058 112.197 1.00 173.65 ?  378 ILE A CG2 1 
ATOM 2589 C CD1 . ILE A 1 396 ? 105.472 112.820 115.023 1.00 173.65 ?  378 ILE A CD1 1 
ATOM 2590 N N   . PHE A 1 397 ? 104.940 114.100 110.142 1.00 171.28 ?  379 PHE A N   1 
ATOM 2591 C CA  . PHE A 1 397 ? 104.850 113.850 108.707 1.00 171.28 ?  379 PHE A CA  1 
ATOM 2592 C C   . PHE A 1 397 ? 105.233 115.099 107.939 1.00 171.28 ?  379 PHE A C   1 
ATOM 2593 O O   . PHE A 1 397 ? 105.965 115.022 106.954 1.00 171.28 ?  379 PHE A O   1 
ATOM 2594 C CB  . PHE A 1 397 ? 103.444 113.395 108.317 1.00 171.28 ?  379 PHE A CB  1 
ATOM 2595 C CG  . PHE A 1 397 ? 103.136 111.978 108.705 1.00 171.28 ?  379 PHE A CG  1 
ATOM 2596 C CD1 . PHE A 1 397 ? 103.917 111.310 109.634 1.00 171.28 ?  379 PHE A CD1 1 
ATOM 2597 C CD2 . PHE A 1 397 ? 102.063 111.312 108.139 1.00 171.28 ?  379 PHE A CD2 1 
ATOM 2598 C CE1 . PHE A 1 397 ? 103.633 110.007 109.992 1.00 171.28 ?  379 PHE A CE1 1 
ATOM 2599 C CE2 . PHE A 1 397 ? 101.775 110.008 108.492 1.00 171.28 ?  379 PHE A CE2 1 
ATOM 2600 C CZ  . PHE A 1 397 ? 102.560 109.356 109.420 1.00 171.28 ?  379 PHE A CZ  1 
ATOM 2601 N N   . GLN A 1 398 ? 104.736 116.252 108.375 1.00 169.74 ?  380 GLN A N   1 
ATOM 2602 C CA  . GLN A 1 398 ? 105.128 117.497 107.740 1.00 169.74 ?  380 GLN A CA  1 
ATOM 2603 C C   . GLN A 1 398 ? 106.633 117.528 107.705 1.00 169.74 ?  380 GLN A C   1 
ATOM 2604 O O   . GLN A 1 398 ? 107.243 117.535 106.634 1.00 169.74 ?  380 GLN A O   1 
ATOM 2605 C CB  . GLN A 1 398 ? 104.611 118.694 108.526 1.00 169.74 ?  380 GLN A CB  1 
ATOM 2606 C CG  . GLN A 1 398 ? 103.108 118.710 108.729 1.00 169.74 ?  380 GLN A CG  1 
ATOM 2607 C CD  . GLN A 1 398 ? 102.706 119.272 110.078 1.00 169.74 ?  380 GLN A CD  1 
ATOM 2608 O OE1 . GLN A 1 398 ? 103.546 119.732 110.851 1.00 169.74 ?  380 GLN A OE1 1 
ATOM 2609 N NE2 . GLN A 1 398 ? 101.411 119.239 110.368 1.00 169.74 ?  380 GLN A NE2 1 
ATOM 2610 N N   . LEU A 1 399 ? 107.240 117.540 108.885 1.00 169.16 ?  381 LEU A N   1 
ATOM 2611 C CA  . LEU A 1 399 ? 108.689 117.531 108.961 1.00 169.16 ?  381 LEU A CA  1 
ATOM 2612 C C   . LEU A 1 399 ? 109.260 116.436 108.086 1.00 169.16 ?  381 LEU A C   1 
ATOM 2613 O O   . LEU A 1 399 ? 110.307 116.623 107.468 1.00 169.16 ?  381 LEU A O   1 
ATOM 2614 C CB  . LEU A 1 399 ? 109.148 117.314 110.402 1.00 169.16 ?  381 LEU A CB  1 
ATOM 2615 C CG  . LEU A 1 399 ? 108.333 117.988 111.504 1.00 169.16 ?  381 LEU A CG  1 
ATOM 2616 C CD1 . LEU A 1 399 ? 108.533 117.260 112.824 1.00 169.16 ?  381 LEU A CD1 1 
ATOM 2617 C CD2 . LEU A 1 399 ? 108.753 119.443 111.630 1.00 169.16 ?  381 LEU A CD2 1 
ATOM 2618 N N   . ILE A 1 400 ? 108.585 115.291 108.016 1.00 173.10 ?  382 ILE A N   1 
ATOM 2619 C CA  . ILE A 1 400 ? 109.176 114.194 107.264 1.00 173.10 ?  382 ILE A CA  1 
ATOM 2620 C C   . ILE A 1 400 ? 109.360 114.599 105.813 1.00 173.10 ?  382 ILE A C   1 
ATOM 2621 O O   . ILE A 1 400 ? 110.458 114.498 105.253 1.00 173.10 ?  382 ILE A O   1 
ATOM 2622 C CB  . ILE A 1 400 ? 108.318 112.932 107.390 1.00 173.10 ?  382 ILE A CB  1 
ATOM 2623 C CG1 . ILE A 1 400 ? 108.650 112.233 108.691 1.00 173.10 ?  382 ILE A CG1 1 
ATOM 2624 C CG2 . ILE A 1 400 ? 108.609 112.002 106.253 1.00 173.10 ?  382 ILE A CG2 1 
ATOM 2625 C CD1 . ILE A 1 400 ? 110.071 111.770 108.743 1.00 173.10 ?  382 ILE A CD1 1 
ATOM 2626 N N   . ASN A 1 401 ? 108.275 115.046 105.183 1.00 184.50 ?  383 ASN A N   1 
ATOM 2627 C CA  . ASN A 1 401 ? 108.350 115.521 103.811 1.00 184.50 ?  383 ASN A CA  1 
ATOM 2628 C C   . ASN A 1 401 ? 109.435 116.561 103.666 1.00 184.50 ?  383 ASN A C   1 
ATOM 2629 O O   . ASN A 1 401 ? 110.256 116.499 102.742 1.00 184.50 ?  383 ASN A O   1 
ATOM 2630 C CB  . ASN A 1 401 ? 107.013 116.117 103.394 1.00 184.50 ?  383 ASN A CB  1 
ATOM 2631 C CG  . ASN A 1 401 ? 105.874 115.173 103.622 1.00 184.50 ?  383 ASN A CG  1 
ATOM 2632 O OD1 . ASN A 1 401 ? 106.071 114.053 104.083 1.00 184.50 ?  383 ASN A OD1 1 
ATOM 2633 N ND2 . ASN A 1 401 ? 104.665 115.623 103.326 1.00 184.50 ?  383 ASN A ND2 1 
ATOM 2634 N N   . TYR A 1 402 ? 109.461 117.517 104.586 1.00 196.20 ?  384 TYR A N   1 
ATOM 2635 C CA  . TYR A 1 402 ? 110.379 118.629 104.451 1.00 196.20 ?  384 TYR A CA  1 
ATOM 2636 C C   . TYR A 1 402 ? 111.815 118.146 104.469 1.00 196.20 ?  384 TYR A C   1 
ATOM 2637 O O   . TYR A 1 402 ? 112.584 118.411 103.541 1.00 196.20 ?  384 TYR A O   1 
ATOM 2638 C CB  . TYR A 1 402 ? 110.139 119.627 105.567 1.00 196.20 ?  384 TYR A CB  1 
ATOM 2639 C CG  . TYR A 1 402 ? 110.239 121.014 105.051 1.00 196.20 ?  384 TYR A CG  1 
ATOM 2640 C CD1 . TYR A 1 402 ? 109.114 121.696 104.615 1.00 196.20 ?  384 TYR A CD1 1 
ATOM 2641 C CD2 . TYR A 1 402 ? 111.473 121.608 104.893 1.00 196.20 ?  384 TYR A CD2 1 
ATOM 2642 C CE1 . TYR A 1 402 ? 109.217 122.974 104.106 1.00 196.20 ?  384 TYR A CE1 1 
ATOM 2643 C CE2 . TYR A 1 402 ? 111.590 122.872 104.383 1.00 196.20 ?  384 TYR A CE2 1 
ATOM 2644 C CZ  . TYR A 1 402 ? 110.466 123.553 103.988 1.00 196.20 ?  384 TYR A CZ  1 
ATOM 2645 O OH  . TYR A 1 402 ? 110.622 124.819 103.489 1.00 196.20 ?  384 TYR A OH  1 
ATOM 2646 N N   . TYR A 1 403 ? 112.190 117.425 105.521 1.00 186.89 ?  385 TYR A N   1 
ATOM 2647 C CA  . TYR A 1 403 ? 113.528 116.867 105.616 1.00 186.89 ?  385 TYR A CA  1 
ATOM 2648 C C   . TYR A 1 403 ? 113.879 116.096 104.359 1.00 186.89 ?  385 TYR A C   1 
ATOM 2649 O O   . TYR A 1 403 ? 114.879 116.379 103.686 1.00 186.89 ?  385 TYR A O   1 
ATOM 2650 C CB  . TYR A 1 403 ? 113.617 115.953 106.831 1.00 186.89 ?  385 TYR A CB  1 
ATOM 2651 C CG  . TYR A 1 403 ? 114.700 114.917 106.723 1.00 186.89 ?  385 TYR A CG  1 
ATOM 2652 C CD1 . TYR A 1 403 ? 115.986 115.201 107.117 1.00 186.89 ?  385 TYR A CD1 1 
ATOM 2653 C CD2 . TYR A 1 403 ? 114.435 113.652 106.241 1.00 186.89 ?  385 TYR A CD2 1 
ATOM 2654 C CE1 . TYR A 1 403 ? 116.975 114.261 107.025 1.00 186.89 ?  385 TYR A CE1 1 
ATOM 2655 C CE2 . TYR A 1 403 ? 115.420 112.713 106.137 1.00 186.89 ?  385 TYR A CE2 1 
ATOM 2656 C CZ  . TYR A 1 403 ? 116.689 113.021 106.533 1.00 186.89 ?  385 TYR A CZ  1 
ATOM 2657 O OH  . TYR A 1 403 ? 117.682 112.082 106.438 1.00 186.89 ?  385 TYR A OH  1 
ATOM 2658 N N   . SER A 1 404 ? 113.044 115.116 104.031 1.00 189.25 ?  386 SER A N   1 
ATOM 2659 C CA  . SER A 1 404 ? 113.374 114.197 102.959 1.00 189.25 ?  386 SER A CA  1 
ATOM 2660 C C   . SER A 1 404 ? 113.623 114.934 101.659 1.00 189.25 ?  386 SER A C   1 
ATOM 2661 O O   . SER A 1 404 ? 114.572 114.620 100.937 1.00 189.25 ?  386 SER A O   1 
ATOM 2662 C CB  . SER A 1 404 ? 112.246 113.190 102.795 1.00 189.25 ?  386 SER A CB  1 
ATOM 2663 O OG  . SER A 1 404 ? 111.207 113.786 102.056 1.00 189.25 ?  386 SER A OG  1 
ATOM 2664 N N   . PHE A 1 405 ? 112.783 115.917 101.341 1.00 195.75 ?  387 PHE A N   1 
ATOM 2665 C CA  . PHE A 1 405 ? 112.901 116.592 100.056 1.00 195.75 ?  387 PHE A CA  1 
ATOM 2666 C C   . PHE A 1 405 ? 114.308 117.130 99.846  1.00 195.75 ?  387 PHE A C   1 
ATOM 2667 O O   . PHE A 1 405 ? 115.005 116.759 98.890  1.00 195.75 ?  387 PHE A O   1 
ATOM 2668 C CB  . PHE A 1 405 ? 111.877 117.716 99.978  1.00 195.75 ?  387 PHE A CB  1 
ATOM 2669 C CG  . PHE A 1 405 ? 112.195 118.743 98.950  1.00 195.75 ?  387 PHE A CG  1 
ATOM 2670 C CD1 . PHE A 1 405 ? 111.932 118.506 97.621  1.00 195.75 ?  387 PHE A CD1 1 
ATOM 2671 C CD2 . PHE A 1 405 ? 112.751 119.951 99.311  1.00 195.75 ?  387 PHE A CD2 1 
ATOM 2672 C CE1 . PHE A 1 405 ? 112.219 119.453 96.670  1.00 195.75 ?  387 PHE A CE1 1 
ATOM 2673 C CE2 . PHE A 1 405 ? 113.040 120.900 98.364  1.00 195.75 ?  387 PHE A CE2 1 
ATOM 2674 C CZ  . PHE A 1 405 ? 112.772 120.652 97.041  1.00 195.75 ?  387 PHE A CZ  1 
ATOM 2675 N N   . SER A 1 406 ? 114.748 118.000 100.747 1.00 202.48 ?  388 SER A N   1 
ATOM 2676 C CA  . SER A 1 406 ? 116.063 118.595 100.587 1.00 202.48 ?  388 SER A CA  1 
ATOM 2677 C C   . SER A 1 406 ? 117.154 117.543 100.682 1.00 202.48 ?  388 SER A C   1 
ATOM 2678 O O   . SER A 1 406 ? 118.172 117.635 99.987  1.00 202.48 ?  388 SER A O   1 
ATOM 2679 C CB  . SER A 1 406 ? 116.278 119.684 101.628 1.00 202.48 ?  388 SER A CB  1 
ATOM 2680 O OG  . SER A 1 406 ? 117.656 119.964 101.765 1.00 202.48 ?  388 SER A OG  1 
ATOM 2681 N N   . TYR A 1 407 ? 116.969 116.532 101.532 1.00 199.97 ?  389 TYR A N   1 
ATOM 2682 C CA  . TYR A 1 407 ? 117.995 115.503 101.622 1.00 199.97 ?  389 TYR A CA  1 
ATOM 2683 C C   . TYR A 1 407 ? 118.186 114.815 100.281 1.00 199.97 ?  389 TYR A C   1 
ATOM 2684 O O   . TYR A 1 407 ? 119.316 114.540 99.863  1.00 199.97 ?  389 TYR A O   1 
ATOM 2685 C CB  . TYR A 1 407 ? 117.622 114.493 102.695 1.00 199.97 ?  389 TYR A CB  1 
ATOM 2686 C CG  . TYR A 1 407 ? 118.632 113.399 102.866 1.00 199.97 ?  389 TYR A CG  1 
ATOM 2687 C CD1 . TYR A 1 407 ? 118.250 112.147 103.297 1.00 199.97 ?  389 TYR A CD1 1 
ATOM 2688 C CD2 . TYR A 1 407 ? 119.968 113.620 102.606 1.00 199.97 ?  389 TYR A CD2 1 
ATOM 2689 C CE1 . TYR A 1 407 ? 119.167 111.146 103.455 1.00 199.97 ?  389 TYR A CE1 1 
ATOM 2690 C CE2 . TYR A 1 407 ? 120.891 112.625 102.758 1.00 199.97 ?  389 TYR A CE2 1 
ATOM 2691 C CZ  . TYR A 1 407 ? 120.487 111.390 103.185 1.00 199.97 ?  389 TYR A CZ  1 
ATOM 2692 O OH  . TYR A 1 407 ? 121.413 110.390 103.343 1.00 199.97 ?  389 TYR A OH  1 
ATOM 2693 N N   . TRP A 1 408 ? 117.095 114.546 99.587  1.00 193.18 ?  390 TRP A N   1 
ATOM 2694 C CA  . TRP A 1 408 ? 117.220 113.844 98.325  1.00 193.18 ?  390 TRP A CA  1 
ATOM 2695 C C   . TRP A 1 408 ? 117.774 114.744 97.245  1.00 193.18 ?  390 TRP A C   1 
ATOM 2696 O O   . TRP A 1 408 ? 118.535 114.282 96.392  1.00 193.18 ?  390 TRP A O   1 
ATOM 2697 C CB  . TRP A 1 408 ? 115.876 113.264 97.926  1.00 193.18 ?  390 TRP A CB  1 
ATOM 2698 C CG  . TRP A 1 408 ? 115.498 112.197 98.852  1.00 193.18 ?  390 TRP A CG  1 
ATOM 2699 C CD1 . TRP A 1 408 ? 114.472 112.207 99.728  1.00 193.18 ?  390 TRP A CD1 1 
ATOM 2700 C CD2 . TRP A 1 408 ? 116.167 110.958 99.032  1.00 193.18 ?  390 TRP A CD2 1 
ATOM 2701 N NE1 . TRP A 1 408 ? 114.445 111.047 100.445 1.00 193.18 ?  390 TRP A NE1 1 
ATOM 2702 C CE2 . TRP A 1 408 ? 115.478 110.256 100.029 1.00 193.18 ?  390 TRP A CE2 1 
ATOM 2703 C CE3 . TRP A 1 408 ? 117.275 110.365 98.435  1.00 193.18 ?  390 TRP A CE3 1 
ATOM 2704 C CZ2 . TRP A 1 408 ? 115.859 108.997 100.449 1.00 193.18 ?  390 TRP A CZ2 1 
ATOM 2705 C CZ3 . TRP A 1 408 ? 117.653 109.117 98.850  1.00 193.18 ?  390 TRP A CZ3 1 
ATOM 2706 C CH2 . TRP A 1 408 ? 116.948 108.443 99.848  1.00 193.18 ?  390 TRP A CH2 1 
ATOM 2707 N N   . PHE A 1 409 ? 117.423 116.023 97.270  1.00 186.17 ?  391 PHE A N   1 
ATOM 2708 C CA  . PHE A 1 409 ? 118.109 116.959 96.391  1.00 186.17 ?  391 PHE A CA  1 
ATOM 2709 C C   . PHE A 1 409 ? 119.613 116.900 96.615  1.00 186.17 ?  391 PHE A C   1 
ATOM 2710 O O   . PHE A 1 409 ? 120.396 116.820 95.658  1.00 186.17 ?  391 PHE A O   1 
ATOM 2711 C CB  . PHE A 1 409 ? 117.585 118.364 96.640  1.00 186.17 ?  391 PHE A CB  1 
ATOM 2712 C CG  . PHE A 1 409 ? 118.062 119.369 95.652  1.00 186.17 ?  391 PHE A CG  1 
ATOM 2713 C CD1 . PHE A 1 409 ? 118.089 120.710 95.977  1.00 186.17 ?  391 PHE A CD1 1 
ATOM 2714 C CD2 . PHE A 1 409 ? 118.471 118.983 94.396  1.00 186.17 ?  391 PHE A CD2 1 
ATOM 2715 C CE1 . PHE A 1 409 ? 118.520 121.646 95.073  1.00 186.17 ?  391 PHE A CE1 1 
ATOM 2716 C CE2 . PHE A 1 409 ? 118.905 119.917 93.488  1.00 186.17 ?  391 PHE A CE2 1 
ATOM 2717 C CZ  . PHE A 1 409 ? 118.929 121.251 93.827  1.00 186.17 ?  391 PHE A CZ  1 
ATOM 2718 N N   . PHE A 1 410 ? 120.000 116.884 97.884  1.00 199.99 ?  392 PHE A N   1 
ATOM 2719 C CA  . PHE A 1 410 ? 121.400 116.755 98.235  1.00 199.99 ?  392 PHE A CA  1 
ATOM 2720 C C   . PHE A 1 410 ? 121.960 115.510 97.595  1.00 199.99 ?  392 PHE A C   1 
ATOM 2721 O O   . PHE A 1 410 ? 123.008 115.548 96.951  1.00 199.99 ?  392 PHE A O   1 
ATOM 2722 C CB  . PHE A 1 410 ? 121.485 116.627 99.746  1.00 199.99 ?  392 PHE A CB  1 
ATOM 2723 C CG  . PHE A 1 410 ? 122.719 117.210 100.347 1.00 199.99 ?  392 PHE A CG  1 
ATOM 2724 C CD1 . PHE A 1 410 ? 122.628 118.218 101.291 1.00 199.99 ?  392 PHE A CD1 1 
ATOM 2725 C CD2 . PHE A 1 410 ? 123.966 116.732 100.000 1.00 199.99 ?  392 PHE A CD2 1 
ATOM 2726 C CE1 . PHE A 1 410 ? 123.762 118.752 101.863 1.00 199.99 ?  392 PHE A CE1 1 
ATOM 2727 C CE2 . PHE A 1 410 ? 125.101 117.262 100.569 1.00 199.99 ?  392 PHE A CE2 1 
ATOM 2728 C CZ  . PHE A 1 410 ? 125.002 118.267 101.506 1.00 199.99 ?  392 PHE A CZ  1 
ATOM 2729 N N   . VAL A 1 411 ? 121.263 114.394 97.780  1.00 194.51 ?  393 VAL A N   1 
ATOM 2730 C CA  . VAL A 1 411 ? 121.711 113.137 97.202  1.00 194.51 ?  393 VAL A CA  1 
ATOM 2731 C C   . VAL A 1 411 ? 121.981 113.312 95.721  1.00 194.51 ?  393 VAL A C   1 
ATOM 2732 O O   . VAL A 1 411 ? 123.100 113.099 95.262  1.00 194.51 ?  393 VAL A O   1 
ATOM 2733 C CB  . VAL A 1 411 ? 120.663 112.030 97.400  1.00 194.51 ?  393 VAL A CB  1 
ATOM 2734 C CG1 . VAL A 1 411 ? 121.067 110.772 96.645  1.00 194.51 ?  393 VAL A CG1 1 
ATOM 2735 C CG2 . VAL A 1 411 ? 120.477 111.739 98.881  1.00 194.51 ?  393 VAL A CG2 1 
ATOM 2736 N N   . GLY A 1 412 ? 120.959 113.709 94.972  1.00 202.02 ?  394 GLY A N   1 
ATOM 2737 C CA  . GLY A 1 412 ? 121.124 113.912 93.545  1.00 202.02 ?  394 GLY A CA  1 
ATOM 2738 C C   . GLY A 1 412 ? 122.395 114.672 93.241  1.00 202.02 ?  394 GLY A C   1 
ATOM 2739 O O   . GLY A 1 412 ? 123.178 114.261 92.386  1.00 202.02 ?  394 GLY A O   1 
ATOM 2740 N N   . LEU A 1 413 ? 122.606 115.781 93.941  1.00 205.70 ?  395 LEU A N   1 
ATOM 2741 C CA  . LEU A 1 413 ? 123.808 116.574 93.732  1.00 205.70 ?  395 LEU A CA  1 
ATOM 2742 C C   . LEU A 1 413 ? 125.039 115.690 93.792  1.00 205.70 ?  395 LEU A C   1 
ATOM 2743 O O   . LEU A 1 413 ? 125.798 115.603 92.827  1.00 205.70 ?  395 LEU A O   1 
ATOM 2744 C CB  . LEU A 1 413 ? 123.902 117.685 94.777  1.00 205.70 ?  395 LEU A CB  1 
ATOM 2745 C CG  . LEU A 1 413 ? 123.219 119.000 94.399  1.00 205.70 ?  395 LEU A CG  1 
ATOM 2746 C CD1 . LEU A 1 413 ? 122.597 118.910 93.014  1.00 205.70 ?  395 LEU A CD1 1 
ATOM 2747 C CD2 . LEU A 1 413 ? 122.174 119.392 95.430  1.00 205.70 ?  395 LEU A CD2 1 
ATOM 2748 N N   . SER A 1 414 ? 125.240 115.028 94.924  1.00 208.34 ?  396 SER A N   1 
ATOM 2749 C CA  . SER A 1 414 ? 126.385 114.138 95.068  1.00 208.34 ?  396 SER A CA  1 
ATOM 2750 C C   . SER A 1 414 ? 126.517 113.222 93.861  1.00 208.34 ?  396 SER A C   1 
ATOM 2751 O O   . SER A 1 414 ? 127.592 113.115 93.272  1.00 208.34 ?  396 SER A O   1 
ATOM 2752 C CB  . SER A 1 414 ? 126.264 113.314 96.352  1.00 208.34 ?  396 SER A CB  1 
ATOM 2753 O OG  . SER A 1 414 ? 125.406 112.200 96.174  1.00 208.34 ?  396 SER A OG  1 
ATOM 2754 N N   . ILE A 1 415 ? 125.425 112.570 93.481  1.00 208.89 ?  397 ILE A N   1 
ATOM 2755 C CA  . ILE A 1 415 ? 125.472 111.625 92.368  1.00 208.89 ?  397 ILE A CA  1 
ATOM 2756 C C   . ILE A 1 415 ? 125.931 112.254 91.061  1.00 208.89 ?  397 ILE A C   1 
ATOM 2757 O O   . ILE A 1 415 ? 126.876 111.778 90.440  1.00 208.89 ?  397 ILE A O   1 
ATOM 2758 C CB  . ILE A 1 415 ? 124.094 110.981 92.120  1.00 208.89 ?  397 ILE A CB  1 
ATOM 2759 C CG1 . ILE A 1 415 ? 123.402 110.661 93.445  1.00 208.89 ?  397 ILE A CG1 1 
ATOM 2760 C CG2 . ILE A 1 415 ? 124.241 109.724 91.277  1.00 208.89 ?  397 ILE A CG2 1 
ATOM 2761 C CD1 . ILE A 1 415 ? 124.132 109.637 94.286  1.00 208.89 ?  397 ILE A CD1 1 
ATOM 2762 N N   . VAL A 1 416 ? 125.266 113.316 90.630  1.00 223.44 ?  398 VAL A N   1 
ATOM 2763 C CA  . VAL A 1 416 ? 125.599 113.900 89.338  1.00 223.44 ?  398 VAL A CA  1 
ATOM 2764 C C   . VAL A 1 416 ? 127.025 114.426 89.357  1.00 223.44 ?  398 VAL A C   1 
ATOM 2765 O O   . VAL A 1 416 ? 127.746 114.343 88.354  1.00 223.44 ?  398 VAL A O   1 
ATOM 2766 C CB  . VAL A 1 416 ? 124.587 114.990 88.948  1.00 223.44 ?  398 VAL A CB  1 
ATOM 2767 C CG1 . VAL A 1 416 ? 124.530 116.061 89.999  1.00 223.44 ?  398 VAL A CG1 1 
ATOM 2768 C CG2 . VAL A 1 416 ? 124.946 115.585 87.600  1.00 223.44 ?  398 VAL A CG2 1 
ATOM 2769 N N   . GLY A 1 417 ? 127.468 114.953 90.498  1.00 219.08 ?  399 GLY A N   1 
ATOM 2770 C CA  . GLY A 1 417 ? 128.868 115.304 90.619  1.00 219.08 ?  399 GLY A CA  1 
ATOM 2771 C C   . GLY A 1 417 ? 129.768 114.100 90.436  1.00 219.08 ?  399 GLY A C   1 
ATOM 2772 O O   . GLY A 1 417 ? 130.797 114.177 89.760  1.00 219.08 ?  399 GLY A O   1 
ATOM 2773 N N   . GLN A 1 418 ? 129.397 112.976 91.052  1.00 220.63 ?  400 GLN A N   1 
ATOM 2774 C CA  . GLN A 1 418 ? 130.139 111.740 90.846  1.00 220.63 ?  400 GLN A CA  1 
ATOM 2775 C C   . GLN A 1 418 ? 130.321 111.476 89.366  1.00 220.63 ?  400 GLN A C   1 
ATOM 2776 O O   . GLN A 1 418 ? 131.432 111.221 88.890  1.00 220.63 ?  400 GLN A O   1 
ATOM 2777 C CB  . GLN A 1 418 ? 129.397 110.574 91.496  1.00 220.63 ?  400 GLN A CB  1 
ATOM 2778 C CG  . GLN A 1 418 ? 130.220 109.317 91.698  1.00 220.63 ?  400 GLN A CG  1 
ATOM 2779 C CD  . GLN A 1 418 ? 130.462 108.518 90.441  1.00 220.63 ?  400 GLN A CD  1 
ATOM 2780 O OE1 . GLN A 1 418 ? 129.768 108.679 89.441  1.00 220.63 ?  400 GLN A OE1 1 
ATOM 2781 N NE2 . GLN A 1 418 ? 131.451 107.634 90.492  1.00 220.63 ?  400 GLN A NE2 1 
ATOM 2782 N N   . LEU A 1 419 ? 129.225 111.533 88.622  1.00 244.90 ?  401 LEU A N   1 
ATOM 2783 C CA  . LEU A 1 419 ? 129.286 111.163 87.216  1.00 244.90 ?  401 LEU A CA  1 
ATOM 2784 C C   . LEU A 1 419 ? 130.147 112.140 86.429  1.00 244.90 ?  401 LEU A C   1 
ATOM 2785 O O   . LEU A 1 419 ? 130.954 111.733 85.586  1.00 244.90 ?  401 LEU A O   1 
ATOM 2786 C CB  . LEU A 1 419 ? 127.881 111.077 86.628  1.00 244.90 ?  401 LEU A CB  1 
ATOM 2787 C CG  . LEU A 1 419 ? 127.138 109.751 86.819  1.00 244.90 ?  401 LEU A CG  1 
ATOM 2788 C CD1 . LEU A 1 419 ? 127.883 108.634 86.108  1.00 244.90 ?  401 LEU A CD1 1 
ATOM 2789 C CD2 . LEU A 1 419 ? 126.910 109.396 88.277  1.00 244.90 ?  401 LEU A CD2 1 
ATOM 2790 N N   . TYR A 1 420 ? 129.984 113.438 86.683  1.00 253.05 ?  402 TYR A N   1 
ATOM 2791 C CA  . TYR A 1 420 ? 130.777 114.406 85.934  1.00 253.05 ?  402 TYR A CA  1 
ATOM 2792 C C   . TYR A 1 420 ? 132.253 114.253 86.241  1.00 253.05 ?  402 TYR A C   1 
ATOM 2793 O O   . TYR A 1 420 ? 133.094 114.410 85.349  1.00 253.05 ?  402 TYR A O   1 
ATOM 2794 C CB  . TYR A 1 420 ? 130.320 115.830 86.230  1.00 253.05 ?  402 TYR A CB  1 
ATOM 2795 C CG  . TYR A 1 420 ? 129.165 116.278 85.366  1.00 253.05 ?  402 TYR A CG  1 
ATOM 2796 C CD1 . TYR A 1 420 ? 128.604 115.425 84.421  1.00 253.05 ?  402 TYR A CD1 1 
ATOM 2797 C CD2 . TYR A 1 420 ? 128.639 117.559 85.483  1.00 253.05 ?  402 TYR A CD2 1 
ATOM 2798 C CE1 . TYR A 1 420 ? 127.543 115.833 83.626  1.00 253.05 ?  402 TYR A CE1 1 
ATOM 2799 C CE2 . TYR A 1 420 ? 127.579 117.977 84.691  1.00 253.05 ?  402 TYR A CE2 1 
ATOM 2800 C CZ  . TYR A 1 420 ? 127.036 117.111 83.765  1.00 253.05 ?  402 TYR A CZ  1 
ATOM 2801 O OH  . TYR A 1 420 ? 125.984 117.529 82.980  1.00 253.05 ?  402 TYR A OH  1 
ATOM 2802 N N   . LEU A 1 421 ? 132.588 113.929 87.485  1.00 221.58 ?  403 LEU A N   1 
ATOM 2803 C CA  . LEU A 1 421 ? 133.972 113.637 87.804  1.00 221.58 ?  403 LEU A CA  1 
ATOM 2804 C C   . LEU A 1 421 ? 134.435 112.341 87.170  1.00 221.58 ?  403 LEU A C   1 
ATOM 2805 O O   . LEU A 1 421 ? 135.633 112.171 86.936  1.00 221.58 ?  403 LEU A O   1 
ATOM 2806 C CB  . LEU A 1 421 ? 134.157 113.576 89.315  1.00 221.58 ?  403 LEU A CB  1 
ATOM 2807 C CG  . LEU A 1 421 ? 135.609 113.633 89.778  1.00 221.58 ?  403 LEU A CG  1 
ATOM 2808 C CD1 . LEU A 1 421 ? 136.384 114.639 88.950  1.00 221.58 ?  403 LEU A CD1 1 
ATOM 2809 C CD2 . LEU A 1 421 ? 135.667 114.001 91.244  1.00 221.58 ?  403 LEU A CD2 1 
ATOM 2810 N N   . ARG A 1 422 ? 133.519 111.423 86.897  1.00 217.55 ?  404 ARG A N   1 
ATOM 2811 C CA  . ARG A 1 422 ? 133.866 110.243 86.127  1.00 217.55 ?  404 ARG A CA  1 
ATOM 2812 C C   . ARG A 1 422 ? 134.235 110.589 84.693  1.00 217.55 ?  404 ARG A C   1 
ATOM 2813 O O   . ARG A 1 422 ? 135.372 110.361 84.275  1.00 217.55 ?  404 ARG A O   1 
ATOM 2814 C CB  . ARG A 1 422 ? 132.708 109.245 86.146  1.00 217.55 ?  404 ARG A CB  1 
ATOM 2815 C CG  . ARG A 1 422 ? 132.635 108.442 87.413  1.00 217.55 ?  404 ARG A CG  1 
ATOM 2816 C CD  . ARG A 1 422 ? 133.779 107.461 87.425  1.00 217.55 ?  404 ARG A CD  1 
ATOM 2817 N NE  . ARG A 1 422 ? 133.790 106.686 86.191  1.00 217.55 ?  404 ARG A NE  1 
ATOM 2818 C CZ  . ARG A 1 422 ? 134.870 106.105 85.684  1.00 217.55 ?  404 ARG A CZ  1 
ATOM 2819 N NH1 . ARG A 1 422 ? 136.031 106.210 86.308  1.00 217.55 1  404 ARG A NH1 1 
ATOM 2820 N NH2 . ARG A 1 422 ? 134.790 105.420 84.553  1.00 217.55 ?  404 ARG A NH2 1 
ATOM 2821 N N   . TRP A 1 423 ? 133.295 111.158 83.938  1.00 232.33 ?  405 TRP A N   1 
ATOM 2822 C CA  . TRP A 1 423 ? 133.563 111.480 82.539  1.00 232.33 ?  405 TRP A CA  1 
ATOM 2823 C C   . TRP A 1 423 ? 134.670 112.515 82.421  1.00 232.33 ?  405 TRP A C   1 
ATOM 2824 O O   . TRP A 1 423 ? 135.759 112.229 81.912  1.00 232.33 ?  405 TRP A O   1 
ATOM 2825 C CB  . TRP A 1 423 ? 132.290 111.977 81.853  1.00 232.33 ?  405 TRP A CB  1 
ATOM 2826 C CG  . TRP A 1 423 ? 132.562 112.944 80.739  1.00 232.33 ?  405 TRP A CG  1 
ATOM 2827 C CD1 . TRP A 1 423 ? 132.356 114.291 80.757  1.00 232.33 ?  405 TRP A CD1 1 
ATOM 2828 C CD2 . TRP A 1 423 ? 133.116 112.641 79.454  1.00 232.33 ?  405 TRP A CD2 1 
ATOM 2829 N NE1 . TRP A 1 423 ? 132.734 114.844 79.560  1.00 232.33 ?  405 TRP A NE1 1 
ATOM 2830 C CE2 . TRP A 1 423 ? 133.205 113.853 78.742  1.00 232.33 ?  405 TRP A CE2 1 
ATOM 2831 C CE3 . TRP A 1 423 ? 133.537 111.462 78.834  1.00 232.33 ?  405 TRP A CE3 1 
ATOM 2832 C CZ2 . TRP A 1 423 ? 133.698 113.920 77.442  1.00 232.33 ?  405 TRP A CZ2 1 
ATOM 2833 C CZ3 . TRP A 1 423 ? 134.027 111.531 77.542  1.00 232.33 ?  405 TRP A CZ3 1 
ATOM 2834 C CH2 . TRP A 1 423 ? 134.103 112.751 76.861  1.00 232.33 ?  405 TRP A CH2 1 
ATOM 2835 N N   . LYS A 1 424 ? 134.414 113.725 82.896  1.00 225.50 ?  406 LYS A N   1 
ATOM 2836 C CA  . LYS A 1 424 ? 135.468 114.716 82.893  1.00 225.50 ?  406 LYS A CA  1 
ATOM 2837 C C   . LYS A 1 424 ? 136.332 114.531 84.127  1.00 225.50 ?  406 LYS A C   1 
ATOM 2838 O O   . LYS A 1 424 ? 135.858 114.152 85.199  1.00 225.50 ?  406 LYS A O   1 
ATOM 2839 C CB  . LYS A 1 424 ? 134.889 116.124 82.817  1.00 225.50 ?  406 LYS A CB  1 
ATOM 2840 C CG  . LYS A 1 424 ? 134.785 116.615 81.390  1.00 225.50 ?  406 LYS A CG  1 
ATOM 2841 C CD  . LYS A 1 424 ? 133.682 117.631 81.214  1.00 225.50 ?  406 LYS A CD  1 
ATOM 2842 C CE  . LYS A 1 424 ? 133.482 117.949 79.742  1.00 225.50 ?  406 LYS A CE  1 
ATOM 2843 N NZ  . LYS A 1 424 ? 132.353 118.890 79.521  1.00 225.50 1  406 LYS A NZ  1 
ATOM 2844 N N   . GLU A 1 425 ? 137.618 114.801 83.957  1.00 230.22 ?  407 GLU A N   1 
ATOM 2845 C CA  . GLU A 1 425 ? 138.652 114.292 84.850  1.00 230.22 ?  407 GLU A CA  1 
ATOM 2846 C C   . GLU A 1 425 ? 138.484 112.779 85.026  1.00 230.22 ?  407 GLU A C   1 
ATOM 2847 O O   . GLU A 1 425 ? 138.158 112.303 86.115  1.00 230.22 ?  407 GLU A O   1 
ATOM 2848 C CB  . GLU A 1 425 ? 138.639 115.011 86.191  1.00 230.22 ?  407 GLU A CB  1 
ATOM 2849 C CG  . GLU A 1 425 ? 139.678 114.520 87.192  1.00 230.22 ?  407 GLU A CG  1 
ATOM 2850 C CD  . GLU A 1 425 ? 141.095 114.614 86.675  1.00 230.22 ?  407 GLU A CD  1 
ATOM 2851 O OE1 . GLU A 1 425 ? 141.374 115.498 85.840  1.00 230.22 ?  407 GLU A OE1 1 
ATOM 2852 O OE2 . GLU A 1 425 ? 141.931 113.787 87.096  1.00 230.22 -1 407 GLU A OE2 1 
ATOM 2853 N N   . PRO A 1 426 ? 138.657 112.008 83.965  1.00 214.26 ?  408 PRO A N   1 
ATOM 2854 C CA  . PRO A 1 426 ? 138.750 110.560 84.136  1.00 214.26 ?  408 PRO A CA  1 
ATOM 2855 C C   . PRO A 1 426 ? 140.145 110.198 84.600  1.00 214.26 ?  408 PRO A C   1 
ATOM 2856 O O   . PRO A 1 426 ? 140.917 111.076 84.996  1.00 214.26 ?  408 PRO A O   1 
ATOM 2857 C CB  . PRO A 1 426 ? 138.455 110.026 82.735  1.00 214.26 ?  408 PRO A CB  1 
ATOM 2858 C CG  . PRO A 1 426 ? 139.031 111.069 81.846  1.00 214.26 ?  408 PRO A CG  1 
ATOM 2859 C CD  . PRO A 1 426 ? 138.863 112.395 82.558  1.00 214.26 ?  408 PRO A CD  1 
ATOM 2860 N N   . ASP A 1 427 ? 140.467 108.910 84.590  1.00 212.93 ?  409 ASP A N   1 
ATOM 2861 C CA  . ASP A 1 427 ? 141.815 108.397 84.779  1.00 212.93 ?  409 ASP A CA  1 
ATOM 2862 C C   . ASP A 1 427 ? 142.329 108.616 86.191  1.00 212.93 ?  409 ASP A C   1 
ATOM 2863 O O   . ASP A 1 427 ? 143.486 108.285 86.467  1.00 212.93 ?  409 ASP A O   1 
ATOM 2864 C CB  . ASP A 1 427 ? 142.803 109.026 83.790  1.00 212.93 ?  409 ASP A CB  1 
ATOM 2865 C CG  . ASP A 1 427 ? 142.399 108.796 82.354  1.00 212.93 ?  409 ASP A CG  1 
ATOM 2866 O OD1 . ASP A 1 427 ? 141.737 107.774 82.083  1.00 212.93 ?  409 ASP A OD1 1 
ATOM 2867 O OD2 . ASP A 1 427 ? 142.724 109.644 81.499  1.00 212.93 -1 409 ASP A OD2 1 
ATOM 2868 N N   . ARG A 1 428 ? 141.528 109.176 87.082  1.00 205.42 ?  410 ARG A N   1 
ATOM 2869 C CA  . ARG A 1 428 ? 141.964 109.352 88.456  1.00 205.42 ?  410 ARG A CA  1 
ATOM 2870 C C   . ARG A 1 428 ? 142.269 107.994 89.070  1.00 205.42 ?  410 ARG A C   1 
ATOM 2871 O O   . ARG A 1 428 ? 141.597 107.009 88.747  1.00 205.42 ?  410 ARG A O   1 
ATOM 2872 C CB  . ARG A 1 428 ? 140.893 110.056 89.272  1.00 205.42 ?  410 ARG A CB  1 
ATOM 2873 C CG  . ARG A 1 428 ? 140.591 111.456 88.813  1.00 205.42 ?  410 ARG A CG  1 
ATOM 2874 C CD  . ARG A 1 428 ? 139.517 112.070 89.680  1.00 205.42 ?  410 ARG A CD  1 
ATOM 2875 N NE  . ARG A 1 428 ? 139.540 111.531 91.036  1.00 205.42 ?  410 ARG A NE  1 
ATOM 2876 C CZ  . ARG A 1 428 ? 140.284 112.020 92.020  1.00 205.42 ?  410 ARG A CZ  1 
ATOM 2877 N NH1 . ARG A 1 428 ? 141.072 113.062 91.798  1.00 205.42 1  410 ARG A NH1 1 
ATOM 2878 N NH2 . ARG A 1 428 ? 140.242 111.470 93.225  1.00 205.42 ?  410 ARG A NH2 1 
ATOM 2879 N N   . PRO A 1 429 ? 143.264 107.894 89.935  1.00 207.33 ?  411 PRO A N   1 
ATOM 2880 C CA  . PRO A 1 429 ? 143.484 106.627 90.632  1.00 207.33 ?  411 PRO A CA  1 
ATOM 2881 C C   . PRO A 1 429 ? 142.291 106.328 91.511  1.00 207.33 ?  411 PRO A C   1 
ATOM 2882 O O   . PRO A 1 429 ? 142.062 106.989 92.526  1.00 207.33 ?  411 PRO A O   1 
ATOM 2883 C CB  . PRO A 1 429 ? 144.751 106.886 91.452  1.00 207.33 ?  411 PRO A CB  1 
ATOM 2884 C CG  . PRO A 1 429 ? 144.772 108.364 91.636  1.00 207.33 ?  411 PRO A CG  1 
ATOM 2885 C CD  . PRO A 1 429 ? 144.194 108.942 90.380  1.00 207.33 ?  411 PRO A CD  1 
ATOM 2886 N N   . ARG A 1 430 ? 141.521 105.330 91.122  1.00 198.06 ?  412 ARG A N   1 
ATOM 2887 C CA  . ARG A 1 430 ? 140.260 105.042 91.788  1.00 198.06 ?  412 ARG A CA  1 
ATOM 2888 C C   . ARG A 1 430 ? 140.270 103.587 92.203  1.00 198.06 ?  412 ARG A C   1 
ATOM 2889 O O   . ARG A 1 430 ? 140.287 102.696 91.334  1.00 198.06 ?  412 ARG A O   1 
ATOM 2890 C CB  . ARG A 1 430 ? 139.084 105.352 90.868  1.00 198.06 ?  412 ARG A CB  1 
ATOM 2891 C CG  . ARG A 1 430 ? 138.996 106.831 90.523  1.00 198.06 ?  412 ARG A CG  1 
ATOM 2892 C CD  . ARG A 1 430 ? 137.782 107.159 89.677  1.00 198.06 ?  412 ARG A CD  1 
ATOM 2893 N NE  . ARG A 1 430 ? 138.064 107.084 88.248  1.00 198.06 ?  412 ARG A NE  1 
ATOM 2894 C CZ  . ARG A 1 430 ? 138.120 108.136 87.439  1.00 198.06 ?  412 ARG A CZ  1 
ATOM 2895 N NH1 . ARG A 1 430 ? 137.918 109.356 87.911  1.00 198.06 1  412 ARG A NH1 1 
ATOM 2896 N NH2 . ARG A 1 430 ? 138.376 107.965 86.154  1.00 198.06 ?  412 ARG A NH2 1 
ATOM 2897 N N   . PRO A 1 431 ? 140.259 103.299 93.483  1.00 191.82 ?  413 PRO A N   1 
ATOM 2898 C CA  . PRO A 1 431 ? 140.429 101.915 93.932  1.00 191.82 ?  413 PRO A CA  1 
ATOM 2899 C C   . PRO A 1 431 ? 139.192 101.069 93.695  1.00 191.82 ?  413 PRO A C   1 
ATOM 2900 O O   . PRO A 1 431 ? 139.073 99.965  94.235  1.00 191.82 ?  413 PRO A O   1 
ATOM 2901 C CB  . PRO A 1 431 ? 140.725 102.072 95.426  1.00 191.82 ?  413 PRO A CB  1 
ATOM 2902 C CG  . PRO A 1 431 ? 140.061 103.342 95.795  1.00 191.82 ?  413 PRO A CG  1 
ATOM 2903 C CD  . PRO A 1 431 ? 140.144 104.242 94.605  1.00 191.82 ?  413 PRO A CD  1 
ATOM 2904 N N   . LEU A 1 432 ? 138.257 101.577 92.900  1.00 199.17 ?  414 LEU A N   1 
ATOM 2905 C CA  . LEU A 1 432 ? 137.052 100.833 92.583  1.00 199.17 ?  414 LEU A CA  1 
ATOM 2906 C C   . LEU A 1 432 ? 136.589 101.189 91.180  1.00 199.17 ?  414 LEU A C   1 
ATOM 2907 O O   . LEU A 1 432 ? 136.762 102.320 90.721  1.00 199.17 ?  414 LEU A O   1 
ATOM 2908 C CB  . LEU A 1 432 ? 135.948 101.125 93.587  1.00 199.17 ?  414 LEU A CB  1 
ATOM 2909 C CG  . LEU A 1 432 ? 135.048 99.924  93.800  1.00 199.17 ?  414 LEU A CG  1 
ATOM 2910 C CD1 . LEU A 1 432 ? 135.886 98.772  94.317  1.00 199.17 ?  414 LEU A CD1 1 
ATOM 2911 C CD2 . LEU A 1 432 ? 133.956 100.281 94.775  1.00 199.17 ?  414 LEU A CD2 1 
ATOM 2912 N N   . LYS A 1 433 ? 136.001 100.207 90.501  1.00 225.36 ?  415 LYS A N   1 
ATOM 2913 C CA  . LYS A 1 433 ? 135.501 100.385 89.142  1.00 225.36 ?  415 LYS A CA  1 
ATOM 2914 C C   . LYS A 1 433 ? 134.123 99.754  89.066  1.00 225.36 ?  415 LYS A C   1 
ATOM 2915 O O   . LYS A 1 433 ? 133.971 98.568  89.370  1.00 225.36 ?  415 LYS A O   1 
ATOM 2916 C CB  . LYS A 1 433 ? 136.426 99.734  88.111  1.00 225.36 ?  415 LYS A CB  1 
ATOM 2917 C CG  . LYS A 1 433 ? 137.896 99.727  88.480  1.00 225.36 ?  415 LYS A CG  1 
ATOM 2918 C CD  . LYS A 1 433 ? 138.577 101.023 88.107  1.00 225.36 ?  415 LYS A CD  1 
ATOM 2919 C CE  . LYS A 1 433 ? 140.082 100.833 88.043  1.00 225.36 ?  415 LYS A CE  1 
ATOM 2920 N NZ  . LYS A 1 433 ? 140.454 99.766  87.072  1.00 225.36 1  415 LYS A NZ  1 
ATOM 2921 N N   . LEU A 1 434 ? 133.125 100.526 88.661  1.00 233.32 ?  416 LEU A N   1 
ATOM 2922 C CA  . LEU A 1 434 ? 131.772 100.008 88.556  1.00 233.32 ?  416 LEU A CA  1 
ATOM 2923 C C   . LEU A 1 434 ? 131.208 100.297 87.180  1.00 233.32 ?  416 LEU A C   1 
ATOM 2924 O O   . LEU A 1 434 ? 131.728 101.123 86.429  1.00 233.32 ?  416 LEU A O   1 
ATOM 2925 C CB  . LEU A 1 434 ? 130.843 100.600 89.612  1.00 233.32 ?  416 LEU A CB  1 
ATOM 2926 C CG  . LEU A 1 434 ? 130.794 99.859  90.943  1.00 233.32 ?  416 LEU A CG  1 
ATOM 2927 C CD1 . LEU A 1 434 ? 130.366 98.426  90.696  1.00 233.32 ?  416 LEU A CD1 1 
ATOM 2928 C CD2 . LEU A 1 434 ? 132.109 99.919  91.685  1.00 233.32 ?  416 LEU A CD2 1 
ATOM 2929 N N   . SER A 1 435 ? 130.130 99.597  86.860  1.00 265.11 ?  417 SER A N   1 
ATOM 2930 C CA  . SER A 1 435 ? 129.399 99.882  85.638  1.00 265.11 ?  417 SER A CA  1 
ATOM 2931 C C   . SER A 1 435 ? 128.784 101.265 85.725  1.00 265.11 ?  417 SER A C   1 
ATOM 2932 O O   . SER A 1 435 ? 128.207 101.633 86.750  1.00 265.11 ?  417 SER A O   1 
ATOM 2933 C CB  . SER A 1 435 ? 128.314 98.834  85.421  1.00 265.11 ?  417 SER A CB  1 
ATOM 2934 O OG  . SER A 1 435 ? 127.189 99.117  86.231  1.00 265.11 ?  417 SER A OG  1 
ATOM 2935 N N   . VAL A 1 436 ? 128.911 102.032 84.641  1.00 296.38 ?  418 VAL A N   1 
ATOM 2936 C CA  . VAL A 1 436 ? 128.405 103.401 84.625  1.00 296.38 ?  418 VAL A CA  1 
ATOM 2937 C C   . VAL A 1 436 ? 126.884 103.414 84.645  1.00 296.38 ?  418 VAL A C   1 
ATOM 2938 O O   . VAL A 1 436 ? 126.264 104.408 85.042  1.00 296.38 ?  418 VAL A O   1 
ATOM 2939 C CB  . VAL A 1 436 ? 128.971 104.149 83.395  1.00 296.38 ?  418 VAL A CB  1 
ATOM 2940 C CG1 . VAL A 1 436 ? 128.407 105.560 83.288  1.00 296.38 ?  418 VAL A CG1 1 
ATOM 2941 C CG2 . VAL A 1 436 ? 130.490 104.181 83.446  1.00 296.38 ?  418 VAL A CG2 1 
ATOM 2942 N N   . PHE A 1 437 ? 126.256 102.309 84.245  1.00 309.96 ?  419 PHE A N   1 
ATOM 2943 C CA  . PHE A 1 437 ? 124.804 102.299 84.116  1.00 309.96 ?  419 PHE A CA  1 
ATOM 2944 C C   . PHE A 1 437 ? 124.116 102.516 85.457  1.00 309.96 ?  419 PHE A C   1 
ATOM 2945 O O   . PHE A 1 437 ? 123.412 103.514 85.640  1.00 309.96 ?  419 PHE A O   1 
ATOM 2946 C CB  . PHE A 1 437 ? 124.340 100.987 83.482  1.00 309.96 ?  419 PHE A CB  1 
ATOM 2947 C CG  . PHE A 1 437 ? 124.704 100.848 82.028  1.00 309.96 ?  419 PHE A CG  1 
ATOM 2948 C CD1 . PHE A 1 437 ? 123.854 101.320 81.040  1.00 309.96 ?  419 PHE A CD1 1 
ATOM 2949 C CD2 . PHE A 1 437 ? 125.888 100.239 81.649  1.00 309.96 ?  419 PHE A CD2 1 
ATOM 2950 C CE1 . PHE A 1 437 ? 124.182 101.192 79.702  1.00 309.96 ?  419 PHE A CE1 1 
ATOM 2951 C CE2 . PHE A 1 437 ? 126.220 100.108 80.312  1.00 309.96 ?  419 PHE A CE2 1 
ATOM 2952 C CZ  . PHE A 1 437 ? 125.366 100.585 79.339  1.00 309.96 ?  419 PHE A CZ  1 
ATOM 2953 N N   . PHE A 1 438 ? 124.325 101.612 86.414  1.00 282.78 ?  420 PHE A N   1 
ATOM 2954 C CA  . PHE A 1 438 ? 123.502 101.604 87.620  1.00 282.78 ?  420 PHE A CA  1 
ATOM 2955 C C   . PHE A 1 438 ? 123.532 102.921 88.399  1.00 282.78 ?  420 PHE A C   1 
ATOM 2956 O O   . PHE A 1 438 ? 122.503 103.295 88.975  1.00 282.78 ?  420 PHE A O   1 
ATOM 2957 C CB  . PHE A 1 438 ? 123.882 100.418 88.521  1.00 282.78 ?  420 PHE A CB  1 
ATOM 2958 C CG  . PHE A 1 438 ? 125.111 100.630 89.342  1.00 282.78 ?  420 PHE A CG  1 
ATOM 2959 C CD1 . PHE A 1 438 ? 126.328 100.159 88.902  1.00 282.78 ?  420 PHE A CD1 1 
ATOM 2960 C CD2 . PHE A 1 438 ? 125.046 101.279 90.563  1.00 282.78 ?  420 PHE A CD2 1 
ATOM 2961 C CE1 . PHE A 1 438 ? 127.458 100.347 89.644  1.00 282.78 ?  420 PHE A CE1 1 
ATOM 2962 C CE2 . PHE A 1 438 ? 126.175 101.474 91.311  1.00 282.78 ?  420 PHE A CE2 1 
ATOM 2963 C CZ  . PHE A 1 438 ? 127.384 101.004 90.853  1.00 282.78 ?  420 PHE A CZ  1 
ATOM 2964 N N   . PRO A 1 439 ? 124.644 103.672 88.446  1.00 294.68 ?  421 PRO A N   1 
ATOM 2965 C CA  . PRO A 1 439 ? 124.563 104.984 89.093  1.00 294.68 ?  421 PRO A CA  1 
ATOM 2966 C C   . PRO A 1 439 ? 123.734 105.954 88.275  1.00 294.68 ?  421 PRO A C   1 
ATOM 2967 O O   . PRO A 1 439 ? 123.071 106.836 88.829  1.00 294.68 ?  421 PRO A O   1 
ATOM 2968 C CB  . PRO A 1 439 ? 126.025 105.426 89.180  1.00 294.68 ?  421 PRO A CB  1 
ATOM 2969 C CG  . PRO A 1 439 ? 126.667 104.738 88.076  1.00 294.68 ?  421 PRO A CG  1 
ATOM 2970 C CD  . PRO A 1 439 ? 126.025 103.400 88.019  1.00 294.68 ?  421 PRO A CD  1 
ATOM 2971 N N   . ILE A 1 440 ? 123.760 105.808 86.953  1.00 304.94 ?  422 ILE A N   1 
ATOM 2972 C CA  . ILE A 1 440 ? 122.907 106.639 86.115  1.00 304.94 ?  422 ILE A CA  1 
ATOM 2973 C C   . ILE A 1 440 ? 121.462 106.337 86.478  1.00 304.94 ?  422 ILE A C   1 
ATOM 2974 O O   . ILE A 1 440 ? 120.669 107.252 86.713  1.00 304.94 ?  422 ILE A O   1 
ATOM 2975 C CB  . ILE A 1 440 ? 123.165 106.411 84.616  1.00 304.94 ?  422 ILE A CB  1 
ATOM 2976 C CG1 . ILE A 1 440 ? 124.577 106.854 84.247  1.00 304.94 ?  422 ILE A CG1 1 
ATOM 2977 C CG2 . ILE A 1 440 ? 122.148 107.172 83.787  1.00 304.94 ?  422 ILE A CG2 1 
ATOM 2978 C CD1 . ILE A 1 440 ? 124.887 106.712 82.778  1.00 304.94 ?  422 ILE A CD1 1 
ATOM 2979 N N   . VAL A 1 441 ? 121.116 105.055 86.543  1.00 305.36 ?  423 VAL A N   1 
ATOM 2980 C CA  . VAL A 1 441 ? 119.769 104.639 86.913  1.00 305.36 ?  423 VAL A CA  1 
ATOM 2981 C C   . VAL A 1 441 ? 119.417 105.241 88.263  1.00 305.36 ?  423 VAL A C   1 
ATOM 2982 O O   . VAL A 1 441 ? 118.278 105.666 88.501  1.00 305.36 ?  423 VAL A O   1 
ATOM 2983 C CB  . VAL A 1 441 ? 119.653 103.108 86.958  1.00 305.36 ?  423 VAL A CB  1 
ATOM 2984 C CG1 . VAL A 1 441 ? 118.196 102.697 86.988  1.00 305.36 ?  423 VAL A CG1 1 
ATOM 2985 C CG2 . VAL A 1 441 ? 120.368 102.490 85.773  1.00 305.36 ?  423 VAL A CG2 1 
ATOM 2986 N N   . PHE A 1 442 ? 120.398 105.270 89.158  1.00 286.43 ?  424 PHE A N   1 
ATOM 2987 C CA  . PHE A 1 442 ? 120.147 105.787 90.489  1.00 286.43 ?  424 PHE A CA  1 
ATOM 2988 C C   . PHE A 1 442 ? 119.820 107.271 90.449  1.00 286.43 ?  424 PHE A C   1 
ATOM 2989 O O   . PHE A 1 442 ? 118.892 107.732 91.119  1.00 286.43 ?  424 PHE A O   1 
ATOM 2990 C CB  . PHE A 1 442 ? 121.345 105.522 91.389  1.00 286.43 ?  424 PHE A CB  1 
ATOM 2991 C CG  . PHE A 1 442 ? 121.067 105.805 92.815  1.00 286.43 ?  424 PHE A CG  1 
ATOM 2992 C CD1 . PHE A 1 442 ? 120.058 105.138 93.461  1.00 286.43 ?  424 PHE A CD1 1 
ATOM 2993 C CD2 . PHE A 1 442 ? 121.784 106.752 93.502  1.00 286.43 ?  424 PHE A CD2 1 
ATOM 2994 C CE1 . PHE A 1 442 ? 119.782 105.389 94.770  1.00 286.43 ?  424 PHE A CE1 1 
ATOM 2995 C CE2 . PHE A 1 442 ? 121.508 107.011 94.815  1.00 286.43 ?  424 PHE A CE2 1 
ATOM 2996 C CZ  . PHE A 1 442 ? 120.496 106.334 95.445  1.00 286.43 ?  424 PHE A CZ  1 
ATOM 2997 N N   . CYS A 1 443 ? 120.569 108.041 89.664  1.00 292.30 ?  425 CYS A N   1 
ATOM 2998 C CA  . CYS A 1 443 ? 120.272 109.466 89.593  1.00 292.30 ?  425 CYS A CA  1 
ATOM 2999 C C   . CYS A 1 443 ? 118.937 109.699 88.901  1.00 292.30 ?  425 CYS A C   1 
ATOM 3000 O O   . CYS A 1 443 ? 118.242 110.679 89.189  1.00 292.30 ?  425 CYS A O   1 
ATOM 3001 C CB  . CYS A 1 443 ? 121.389 110.233 88.886  1.00 292.30 ?  425 CYS A CB  1 
ATOM 3002 S SG  . CYS A 1 443 ? 121.559 109.960 87.121  1.00 292.30 ?  425 CYS A SG  1 
ATOM 3003 N N   . LEU A 1 444 ? 118.545 108.788 88.007  1.00 291.70 ?  426 LEU A N   1 
ATOM 3004 C CA  . LEU A 1 444 ? 117.218 108.885 87.401  1.00 291.70 ?  426 LEU A CA  1 
ATOM 3005 C C   . LEU A 1 444 ? 116.125 108.702 88.442  1.00 291.70 ?  426 LEU A C   1 
ATOM 3006 O O   . LEU A 1 444 ? 115.192 109.507 88.537  1.00 291.70 ?  426 LEU A O   1 
ATOM 3007 C CB  . LEU A 1 444 ? 117.048 107.857 86.283  1.00 291.70 ?  426 LEU A CB  1 
ATOM 3008 C CG  . LEU A 1 444 ? 118.166 107.672 85.266  1.00 291.70 ?  426 LEU A CG  1 
ATOM 3009 C CD1 . LEU A 1 444 ? 117.772 106.666 84.206  1.00 291.70 ?  426 LEU A CD1 1 
ATOM 3010 C CD2 . LEU A 1 444 ? 118.532 109.002 84.640  1.00 291.70 ?  426 LEU A CD2 1 
ATOM 3011 N N   . CYS A 1 445 ? 116.202 107.626 89.214  1.00 270.36 ?  427 CYS A N   1 
ATOM 3012 C CA  . CYS A 1 445 ? 115.173 107.452 90.226  1.00 270.36 ?  427 CYS A CA  1 
ATOM 3013 C C   . CYS A 1 445 ? 115.227 108.546 91.285  1.00 270.36 ?  427 CYS A C   1 
ATOM 3014 O O   . CYS A 1 445 ? 114.185 108.900 91.849  1.00 270.36 ?  427 CYS A O   1 
ATOM 3015 C CB  . CYS A 1 445 ? 115.278 106.050 90.812  1.00 270.36 ?  427 CYS A CB  1 
ATOM 3016 S SG  . CYS A 1 445 ? 116.875 105.602 91.463  1.00 270.36 ?  427 CYS A SG  1 
ATOM 3017 N N   . THR A 1 446 ? 116.388 109.157 91.495  1.00 263.79 ?  428 THR A N   1 
ATOM 3018 C CA  . THR A 1 446 ? 116.487 110.337 92.343  1.00 263.79 ?  428 THR A CA  1 
ATOM 3019 C C   . THR A 1 446 ? 115.710 111.519 91.787  1.00 263.79 ?  428 THR A C   1 
ATOM 3020 O O   . THR A 1 446 ? 114.922 112.149 92.503  1.00 263.79 ?  428 THR A O   1 
ATOM 3021 C CB  . THR A 1 446 ? 117.945 110.749 92.514  1.00 263.79 ?  428 THR A CB  1 
ATOM 3022 O OG1 . THR A 1 446 ? 118.625 109.779 93.315  1.00 263.79 ?  428 THR A OG1 1 
ATOM 3023 C CG2 . THR A 1 446 ? 118.030 112.098 93.179  1.00 263.79 ?  428 THR A CG2 1 
ATOM 3024 N N   . ILE A 1 447 ? 115.964 111.861 90.529  1.00 244.13 ?  429 ILE A N   1 
ATOM 3025 C CA  . ILE A 1 447 ? 115.330 113.033 89.948  1.00 244.13 ?  429 ILE A CA  1 
ATOM 3026 C C   . ILE A 1 447 ? 113.833 112.777 89.913  1.00 244.13 ?  429 ILE A C   1 
ATOM 3027 O O   . ILE A 1 447 ? 113.033 113.704 90.053  1.00 244.13 ?  429 ILE A O   1 
ATOM 3028 C CB  . ILE A 1 447 ? 115.893 113.366 88.557  1.00 244.13 ?  429 ILE A CB  1 
ATOM 3029 C CG1 . ILE A 1 447 ? 115.215 114.611 88.003  1.00 244.13 ?  429 ILE A CG1 1 
ATOM 3030 C CG2 . ILE A 1 447 ? 115.689 112.239 87.600  1.00 244.13 ?  429 ILE A CG2 1 
ATOM 3031 C CD1 . ILE A 1 447 ? 115.508 115.844 88.801  1.00 244.13 ?  429 ILE A CD1 1 
ATOM 3032 N N   . PHE A 1 448 ? 113.442 111.511 89.773  1.00 234.24 ?  430 PHE A N   1 
ATOM 3033 C CA  . PHE A 1 448 ? 112.042 111.144 89.958  1.00 234.24 ?  430 PHE A CA  1 
ATOM 3034 C C   . PHE A 1 448 ? 111.559 111.562 91.339  1.00 234.24 ?  430 PHE A C   1 
ATOM 3035 O O   . PHE A 1 448 ? 110.610 112.346 91.490  1.00 234.24 ?  430 PHE A O   1 
ATOM 3036 C CB  . PHE A 1 448 ? 111.885 109.631 89.756  1.00 234.24 ?  430 PHE A CB  1 
ATOM 3037 C CG  . PHE A 1 448 ? 110.589 109.054 90.284  1.00 234.24 ?  430 PHE A CG  1 
ATOM 3038 C CD1 . PHE A 1 448 ? 109.513 108.862 89.441  1.00 234.24 ?  430 PHE A CD1 1 
ATOM 3039 C CD2 . PHE A 1 448 ? 110.469 108.655 91.606  1.00 234.24 ?  430 PHE A CD2 1 
ATOM 3040 C CE1 . PHE A 1 448 ? 108.338 108.319 89.911  1.00 234.24 ?  430 PHE A CE1 1 
ATOM 3041 C CE2 . PHE A 1 448 ? 109.296 108.121 92.079  1.00 234.24 ?  430 PHE A CE2 1 
ATOM 3042 C CZ  . PHE A 1 448 ? 108.232 107.949 91.232  1.00 234.24 ?  430 PHE A CZ  1 
ATOM 3043 N N   . LEU A 1 449 ? 112.212 111.040 92.364  1.00 229.33 ?  431 LEU A N   1 
ATOM 3044 C CA  . LEU A 1 449 ? 111.749 111.221 93.726  1.00 229.33 ?  431 LEU A CA  1 
ATOM 3045 C C   . LEU A 1 449 ? 111.781 112.662 94.164  1.00 229.33 ?  431 LEU A C   1 
ATOM 3046 O O   . LEU A 1 449 ? 111.164 113.071 95.146  1.00 229.33 ?  431 LEU A O   1 
ATOM 3047 C CB  . LEU A 1 449 ? 112.596 110.354 94.649  1.00 229.33 ?  431 LEU A CB  1 
ATOM 3048 C CG  . LEU A 1 449 ? 112.297 110.393 96.139  1.00 229.33 ?  431 LEU A CG  1 
ATOM 3049 C CD1 . LEU A 1 449 ? 110.816 110.287 96.376  1.00 229.33 ?  431 LEU A CD1 1 
ATOM 3050 C CD2 . LEU A 1 449 ? 113.008 109.257 96.810  1.00 229.33 ?  431 LEU A CD2 1 
ATOM 3051 N N   . VAL A 1 450 ? 112.496 113.526 93.449  1.00 219.19 ?  432 VAL A N   1 
ATOM 3052 C CA  . VAL A 1 450 ? 112.441 114.953 93.725  1.00 219.19 ?  432 VAL A CA  1 
ATOM 3053 C C   . VAL A 1 450 ? 111.473 115.685 92.813  1.00 219.19 ?  432 VAL A C   1 
ATOM 3054 O O   . VAL A 1 450 ? 110.978 116.747 93.185  1.00 219.19 ?  432 VAL A O   1 
ATOM 3055 C CB  . VAL A 1 450 ? 113.832 115.605 93.647  1.00 219.19 ?  432 VAL A CB  1 
ATOM 3056 C CG1 . VAL A 1 450 ? 114.284 115.682 92.219  1.00 219.19 ?  432 VAL A CG1 1 
ATOM 3057 C CG2 . VAL A 1 450 ? 113.799 116.987 94.263  1.00 219.19 ?  432 VAL A CG2 1 
ATOM 3058 N N   . ALA A 1 451 ? 111.155 115.141 91.644  1.00 222.66 ?  433 ALA A N   1 
ATOM 3059 C CA  . ALA A 1 451 ? 110.286 115.841 90.712  1.00 222.66 ?  433 ALA A CA  1 
ATOM 3060 C C   . ALA A 1 451 ? 108.831 115.654 91.092  1.00 222.66 ?  433 ALA A C   1 
ATOM 3061 O O   . ALA A 1 451 ? 108.082 116.627 91.219  1.00 222.66 ?  433 ALA A O   1 
ATOM 3062 C CB  . ALA A 1 451 ? 110.525 115.345 89.287  1.00 222.66 ?  433 ALA A CB  1 
ATOM 3063 N N   . VAL A 1 452 ? 108.433 114.405 91.297  1.00 208.63 ?  434 VAL A N   1 
ATOM 3064 C CA  . VAL A 1 452 ? 107.027 114.092 91.548  1.00 208.63 ?  434 VAL A CA  1 
ATOM 3065 C C   . VAL A 1 452 ? 106.438 114.849 92.741  1.00 208.63 ?  434 VAL A C   1 
ATOM 3066 O O   . VAL A 1 452 ? 105.251 115.201 92.693  1.00 208.63 ?  434 VAL A O   1 
ATOM 3067 C CB  . VAL A 1 452 ? 106.824 112.573 91.682  1.00 208.63 ?  434 VAL A CB  1 
ATOM 3068 C CG1 . VAL A 1 452 ? 107.815 111.958 92.626  1.00 208.63 ?  434 VAL A CG1 1 
ATOM 3069 C CG2 . VAL A 1 452 ? 105.417 112.258 92.135  1.00 208.63 ?  434 VAL A CG2 1 
ATOM 3070 N N   . PRO A 1 453 ? 107.186 115.180 93.804  1.00 207.42 ?  435 PRO A N   1 
ATOM 3071 C CA  . PRO A 1 453 ? 106.557 115.941 94.887  1.00 207.42 ?  435 PRO A CA  1 
ATOM 3072 C C   . PRO A 1 453 ? 106.473 117.431 94.611  1.00 207.42 ?  435 PRO A C   1 
ATOM 3073 O O   . PRO A 1 453 ? 106.384 118.228 95.548  1.00 207.42 ?  435 PRO A O   1 
ATOM 3074 C CB  . PRO A 1 453 ? 107.466 115.653 96.079  1.00 207.42 ?  435 PRO A CB  1 
ATOM 3075 C CG  . PRO A 1 453 ? 108.770 115.545 95.472  1.00 207.42 ?  435 PRO A CG  1 
ATOM 3076 C CD  . PRO A 1 453 ? 108.553 114.797 94.196  1.00 207.42 ?  435 PRO A CD  1 
ATOM 3077 N N   . LEU A 1 454 ? 106.559 117.835 93.348  1.00 208.64 ?  436 LEU A N   1 
ATOM 3078 C CA  . LEU A 1 454 ? 106.275 119.227 93.027  1.00 208.64 ?  436 LEU A CA  1 
ATOM 3079 C C   . LEU A 1 454 ? 104.792 119.439 92.780  1.00 208.64 ?  436 LEU A C   1 
ATOM 3080 O O   . LEU A 1 454 ? 104.185 120.303 93.417  1.00 208.64 ?  436 LEU A O   1 
ATOM 3081 C CB  . LEU A 1 454 ? 107.085 119.698 91.826  1.00 208.64 ?  436 LEU A CB  1 
ATOM 3082 C CG  . LEU A 1 454 ? 108.367 120.408 92.236  1.00 208.64 ?  436 LEU A CG  1 
ATOM 3083 C CD1 . LEU A 1 454 ? 108.007 121.684 92.961  1.00 208.64 ?  436 LEU A CD1 1 
ATOM 3084 C CD2 . LEU A 1 454 ? 109.195 119.522 93.126  1.00 208.64 ?  436 LEU A CD2 1 
ATOM 3085 N N   . TYR A 1 455 ? 104.208 118.678 91.849  1.00 229.28 ?  437 TYR A N   1 
ATOM 3086 C CA  . TYR A 1 455 ? 102.762 118.684 91.665  1.00 229.28 ?  437 TYR A CA  1 
ATOM 3087 C C   . TYR A 1 455 ? 102.088 118.621 93.021  1.00 229.28 ?  437 TYR A C   1 
ATOM 3088 O O   . TYR A 1 455 ? 101.404 119.560 93.439  1.00 229.28 ?  437 TYR A O   1 
ATOM 3089 C CB  . TYR A 1 455 ? 102.288 117.494 90.829  1.00 229.28 ?  437 TYR A CB  1 
ATOM 3090 C CG  . TYR A 1 455 ? 102.535 117.569 89.340  1.00 229.28 ?  437 TYR A CG  1 
ATOM 3091 C CD1 . TYR A 1 455 ? 102.895 118.758 88.724  1.00 229.28 ?  437 TYR A CD1 1 
ATOM 3092 C CD2 . TYR A 1 455 ? 102.370 116.442 88.544  1.00 229.28 ?  437 TYR A CD2 1 
ATOM 3093 C CE1 . TYR A 1 455 ? 103.106 118.814 87.357  1.00 229.28 ?  437 TYR A CE1 1 
ATOM 3094 C CE2 . TYR A 1 455 ? 102.577 116.487 87.184  1.00 229.28 ?  437 TYR A CE2 1 
ATOM 3095 C CZ  . TYR A 1 455 ? 102.945 117.672 86.594  1.00 229.28 ?  437 TYR A CZ  1 
ATOM 3096 O OH  . TYR A 1 455 ? 103.150 117.710 85.234  1.00 229.28 ?  437 TYR A OH  1 
ATOM 3097 N N   . SER A 1 456 ? 102.324 117.528 93.728  1.00 215.16 ?  438 SER A N   1 
ATOM 3098 C CA  . SER A 1 456 ? 101.814 117.346 95.072  1.00 215.16 ?  438 SER A CA  1 
ATOM 3099 C C   . SER A 1 456 ? 102.629 118.233 95.996  1.00 215.16 ?  438 SER A C   1 
ATOM 3100 O O   . SER A 1 456 ? 103.841 118.050 96.122  1.00 215.16 ?  438 SER A O   1 
ATOM 3101 C CB  . SER A 1 456 ? 101.915 115.882 95.488  1.00 215.16 ?  438 SER A CB  1 
ATOM 3102 O OG  . SER A 1 456 ? 101.547 115.045 94.411  1.00 215.16 ?  438 SER A OG  1 
ATOM 3103 N N   . ASP A 1 457 ? 101.966 119.197 96.631  1.00 231.49 ?  439 ASP A N   1 
ATOM 3104 C CA  . ASP A 1 457 ? 102.616 120.116 97.557  1.00 231.49 ?  439 ASP A CA  1 
ATOM 3105 C C   . ASP A 1 457 ? 103.749 120.877 96.867  1.00 231.49 ?  439 ASP A C   1 
ATOM 3106 O O   . ASP A 1 457 ? 104.936 120.656 97.106  1.00 231.49 ?  439 ASP A O   1 
ATOM 3107 C CB  . ASP A 1 457 ? 103.141 119.397 98.801  1.00 231.49 ?  439 ASP A CB  1 
ATOM 3108 C CG  . ASP A 1 457 ? 103.550 120.367 99.888  1.00 231.49 ?  439 ASP A CG  1 
ATOM 3109 O OD1 . ASP A 1 457 ? 102.971 120.312 100.991 1.00 231.49 ?  439 ASP A OD1 1 
ATOM 3110 O OD2 . ASP A 1 457 ? 104.428 121.213 99.633  1.00 231.49 -1 439 ASP A OD2 1 
ATOM 3111 N N   . THR A 1 458 ? 103.343 121.748 95.953  1.00 226.61 ?  440 THR A N   1 
ATOM 3112 C CA  . THR A 1 458 ? 104.276 122.753 95.472  1.00 226.61 ?  440 THR A CA  1 
ATOM 3113 C C   . THR A 1 458 ? 104.846 123.578 96.619  1.00 226.61 ?  440 THR A C   1 
ATOM 3114 O O   . THR A 1 458 ? 105.994 124.030 96.551  1.00 226.61 ?  440 THR A O   1 
ATOM 3115 C CB  . THR A 1 458 ? 103.574 123.672 94.484  1.00 226.61 ?  440 THR A CB  1 
ATOM 3116 O OG1 . THR A 1 458 ? 102.830 124.650 95.216  1.00 226.61 ?  440 THR A OG1 1 
ATOM 3117 C CG2 . THR A 1 458 ? 102.608 122.878 93.631  1.00 226.61 ?  440 THR A CG2 1 
ATOM 3118 N N   . ILE A 1 459 ? 104.075 123.755 97.693  1.00 220.65 ?  441 ILE A N   1 
ATOM 3119 C CA  . ILE A 1 459 ? 104.361 124.817 98.655  1.00 220.65 ?  441 ILE A CA  1 
ATOM 3120 C C   . ILE A 1 459 ? 105.591 124.490 99.491  1.00 220.65 ?  441 ILE A C   1 
ATOM 3121 O O   . ILE A 1 459 ? 106.476 125.333 99.676  1.00 220.65 ?  441 ILE A O   1 
ATOM 3122 C CB  . ILE A 1 459 ? 103.136 125.074 99.545  1.00 220.65 ?  441 ILE A CB  1 
ATOM 3123 C CG1 . ILE A 1 459 ? 102.487 123.750 99.942  1.00 220.65 ?  441 ILE A CG1 1 
ATOM 3124 C CG2 . ILE A 1 459 ? 102.143 125.961 98.828  1.00 220.65 ?  441 ILE A CG2 1 
ATOM 3125 C CD1 . ILE A 1 459 ? 101.409 123.890 100.985 1.00 220.65 ?  441 ILE A CD1 1 
ATOM 3126 N N   . ASN A 1 460 ? 105.644 123.284 100.057 1.00 208.35 ?  442 ASN A N   1 
ATOM 3127 C CA  . ASN A 1 460 ? 106.744 122.982 100.964 1.00 208.35 ?  442 ASN A CA  1 
ATOM 3128 C C   . ASN A 1 460 ? 108.053 122.888 100.204 1.00 208.35 ?  442 ASN A C   1 
ATOM 3129 O O   . ASN A 1 460 ? 109.091 123.360 100.679 1.00 208.35 ?  442 ASN A O   1 
ATOM 3130 C CB  . ASN A 1 460 ? 106.470 121.695 101.734 1.00 208.35 ?  442 ASN A CB  1 
ATOM 3131 C CG  . ASN A 1 460 ? 105.229 121.793 102.588 1.00 208.35 ?  442 ASN A CG  1 
ATOM 3132 O OD1 . ASN A 1 460 ? 104.929 122.846 103.142 1.00 208.35 ?  442 ASN A OD1 1 
ATOM 3133 N ND2 . ASN A 1 460 ? 104.506 120.690 102.712 1.00 208.35 ?  442 ASN A ND2 1 
ATOM 3134 N N   . SER A 1 461 ? 108.022 122.281 99.023  1.00 215.91 ?  443 SER A N   1 
ATOM 3135 C CA  . SER A 1 461 ? 109.183 122.333 98.152  1.00 215.91 ?  443 SER A CA  1 
ATOM 3136 C C   . SER A 1 461 ? 109.594 123.773 97.895  1.00 215.91 ?  443 SER A C   1 
ATOM 3137 O O   . SER A 1 461 ? 110.785 124.112 97.948  1.00 215.91 ?  443 SER A O   1 
ATOM 3138 C CB  . SER A 1 461 ? 108.868 121.619 96.844  1.00 215.91 ?  443 SER A CB  1 
ATOM 3139 O OG  . SER A 1 461 ? 107.813 122.281 96.174  1.00 215.91 ?  443 SER A OG  1 
ATOM 3140 N N   . LEU A 1 462 ? 108.615 124.638 97.634  1.00 221.98 ?  444 LEU A N   1 
ATOM 3141 C CA  . LEU A 1 462 ? 108.917 126.034 97.353  1.00 221.98 ?  444 LEU A CA  1 
ATOM 3142 C C   . LEU A 1 462 ? 109.646 126.677 98.520  1.00 221.98 ?  444 LEU A C   1 
ATOM 3143 O O   . LEU A 1 462 ? 110.675 127.332 98.341  1.00 221.98 ?  444 LEU A O   1 
ATOM 3144 C CB  . LEU A 1 462 ? 107.626 126.787 97.032  1.00 221.98 ?  444 LEU A CB  1 
ATOM 3145 C CG  . LEU A 1 462 ? 107.669 128.315 96.935  1.00 221.98 ?  444 LEU A CG  1 
ATOM 3146 C CD1 . LEU A 1 462 ? 106.678 128.787 95.892  1.00 221.98 ?  444 LEU A CD1 1 
ATOM 3147 C CD2 . LEU A 1 462 ? 107.349 128.974 98.270  1.00 221.98 ?  444 LEU A CD2 1 
ATOM 3148 N N   . ILE A 1 463 ? 109.129 126.494 99.730  1.00 208.97 ?  445 ILE A N   1 
ATOM 3149 C CA  . ILE A 1 463 ? 109.725 127.182 100.868 1.00 208.97 ?  445 ILE A CA  1 
ATOM 3150 C C   . ILE A 1 463 ? 111.060 126.558 101.249 1.00 208.97 ?  445 ILE A C   1 
ATOM 3151 O O   . ILE A 1 463 ? 111.947 127.243 101.778 1.00 208.97 ?  445 ILE A O   1 
ATOM 3152 C CB  . ILE A 1 463 ? 108.732 127.225 102.041 1.00 208.97 ?  445 ILE A CB  1 
ATOM 3153 C CG1 . ILE A 1 463 ? 108.158 125.844 102.312 1.00 208.97 ?  445 ILE A CG1 1 
ATOM 3154 C CG2 . ILE A 1 463 ? 107.609 128.192 101.750 1.00 208.97 ?  445 ILE A CG2 1 
ATOM 3155 C CD1 . ILE A 1 463 ? 107.224 125.805 103.488 1.00 208.97 ?  445 ILE A CD1 1 
ATOM 3156 N N   . GLY A 1 464 ? 111.240 125.266 100.990 1.00 207.50 ?  446 GLY A N   1 
ATOM 3157 C CA  . GLY A 1 464 ? 112.565 124.693 101.125 1.00 207.50 ?  446 GLY A CA  1 
ATOM 3158 C C   . GLY A 1 464 ? 113.559 125.384 100.218 1.00 207.50 ?  446 GLY A C   1 
ATOM 3159 O O   . GLY A 1 464 ? 114.635 125.807 100.648 1.00 207.50 ?  446 GLY A O   1 
ATOM 3160 N N   . ILE A 1 465 ? 113.202 125.521 98.944  1.00 217.40 ?  447 ILE A N   1 
ATOM 3161 C CA  . ILE A 1 465 ? 114.066 126.266 98.041  1.00 217.40 ?  447 ILE A CA  1 
ATOM 3162 C C   . ILE A 1 465 ? 114.222 127.695 98.527  1.00 217.40 ?  447 ILE A C   1 
ATOM 3163 O O   . ILE A 1 465 ? 115.260 128.327 98.308  1.00 217.40 ?  447 ILE A O   1 
ATOM 3164 C CB  . ILE A 1 465 ? 113.512 126.207 96.610  1.00 217.40 ?  447 ILE A CB  1 
ATOM 3165 C CG1 . ILE A 1 465 ? 113.329 124.754 96.185  1.00 217.40 ?  447 ILE A CG1 1 
ATOM 3166 C CG2 . ILE A 1 465 ? 114.451 126.901 95.652  1.00 217.40 ?  447 ILE A CG2 1 
ATOM 3167 C CD1 . ILE A 1 465 ? 114.576 123.924 96.344  1.00 217.40 ?  447 ILE A CD1 1 
ATOM 3168 N N   . ALA A 1 466 ? 113.209 128.219 99.207  1.00 227.64 ?  448 ALA A N   1 
ATOM 3169 C CA  . ALA A 1 466 ? 113.269 129.594 99.679  1.00 227.64 ?  448 ALA A CA  1 
ATOM 3170 C C   . ALA A 1 466 ? 114.358 129.762 100.725 1.00 227.64 ?  448 ALA A C   1 
ATOM 3171 O O   . ALA A 1 466 ? 115.187 130.672 100.634 1.00 227.64 ?  448 ALA A O   1 
ATOM 3172 C CB  . ALA A 1 466 ? 111.912 130.014 100.240 1.00 227.64 ?  448 ALA A CB  1 
ATOM 3173 N N   . ILE A 1 467 ? 114.371 128.897 101.733 1.00 230.18 ?  449 ILE A N   1 
ATOM 3174 C CA  . ILE A 1 467 ? 115.430 128.994 102.731 1.00 230.18 ?  449 ILE A CA  1 
ATOM 3175 C C   . ILE A 1 467 ? 116.780 128.690 102.098 1.00 230.18 ?  449 ILE A C   1 
ATOM 3176 O O   . ILE A 1 467 ? 117.799 129.326 102.420 1.00 230.18 ?  449 ILE A O   1 
ATOM 3177 C CB  . ILE A 1 467 ? 115.137 128.084 103.933 1.00 230.18 ?  449 ILE A CB  1 
ATOM 3178 C CG1 . ILE A 1 467 ? 116.329 128.087 104.883 1.00 230.18 ?  449 ILE A CG1 1 
ATOM 3179 C CG2 . ILE A 1 467 ? 114.807 126.687 103.492 1.00 230.18 ?  449 ILE A CG2 1 
ATOM 3180 C CD1 . ILE A 1 467 ? 116.004 127.574 106.250 1.00 230.18 ?  449 ILE A CD1 1 
ATOM 3181 N N   . ALA A 1 468 ? 116.808 127.738 101.166 1.00 232.24 ?  450 ALA A N   1 
ATOM 3182 C CA  . ALA A 1 468 ? 118.030 127.477 100.423 1.00 232.24 ?  450 ALA A CA  1 
ATOM 3183 C C   . ALA A 1 468 ? 118.594 128.769 99.855  1.00 232.24 ?  450 ALA A C   1 
ATOM 3184 O O   . ALA A 1 468 ? 119.690 129.205 100.222 1.00 232.24 ?  450 ALA A O   1 
ATOM 3185 C CB  . ALA A 1 468 ? 117.750 126.473 99.308  1.00 232.24 ?  450 ALA A CB  1 
ATOM 3186 N N   . LEU A 1 469 ? 117.823 129.421 98.988  1.00 247.12 ?  451 LEU A N   1 
ATOM 3187 C CA  . LEU A 1 469 ? 118.297 130.639 98.347  1.00 247.12 ?  451 LEU A CA  1 
ATOM 3188 C C   . LEU A 1 469 ? 118.605 131.722 99.366  1.00 247.12 ?  451 LEU A C   1 
ATOM 3189 O O   . LEU A 1 469 ? 119.548 132.497 99.175  1.00 247.12 ?  451 LEU A O   1 
ATOM 3190 C CB  . LEU A 1 469 ? 117.271 131.129 97.327  1.00 247.12 ?  451 LEU A CB  1 
ATOM 3191 C CG  . LEU A 1 469 ? 115.864 131.508 97.796  1.00 247.12 ?  451 LEU A CG  1 
ATOM 3192 C CD1 . LEU A 1 469 ? 115.770 132.968 98.237  1.00 247.12 ?  451 LEU A CD1 1 
ATOM 3193 C CD2 . LEU A 1 469 ? 114.840 131.204 96.717  1.00 247.12 ?  451 LEU A CD2 1 
ATOM 3194 N N   . SER A 1 470 ? 117.835 131.789 100.451 1.00 245.28 ?  452 SER A N   1 
ATOM 3195 C CA  . SER A 1 470 ? 118.155 132.716 101.521 1.00 245.28 ?  452 SER A CA  1 
ATOM 3196 C C   . SER A 1 470 ? 119.563 132.502 102.039 1.00 245.28 ?  452 SER A C   1 
ATOM 3197 O O   . SER A 1 470 ? 120.189 133.449 102.523 1.00 245.28 ?  452 SER A O   1 
ATOM 3198 C CB  . SER A 1 470 ? 117.164 132.550 102.662 1.00 245.28 ?  452 SER A CB  1 
ATOM 3199 O OG  . SER A 1 470 ? 117.423 131.342 103.348 1.00 245.28 ?  452 SER A OG  1 
ATOM 3200 N N   . GLY A 1 471 ? 120.057 131.271 101.961 1.00 230.48 ?  453 GLY A N   1 
ATOM 3201 C CA  . GLY A 1 471 ? 121.441 131.024 102.324 1.00 230.48 ?  453 GLY A CA  1 
ATOM 3202 C C   . GLY A 1 471 ? 122.435 131.927 101.617 1.00 230.48 ?  453 GLY A C   1 
ATOM 3203 O O   . GLY A 1 471 ? 123.440 132.332 102.206 1.00 230.48 ?  453 GLY A O   1 
ATOM 3204 N N   . LEU A 1 472 ? 122.155 132.281 100.370 1.00 240.99 ?  454 LEU A N   1 
ATOM 3205 C CA  . LEU A 1 472 ? 123.138 132.840 99.447  1.00 240.99 ?  454 LEU A CA  1 
ATOM 3206 C C   . LEU A 1 472 ? 123.524 134.297 99.701  1.00 240.99 ?  454 LEU A C   1 
ATOM 3207 O O   . LEU A 1 472 ? 124.704 134.649 99.543  1.00 240.99 ?  454 LEU A O   1 
ATOM 3208 C CB  . LEU A 1 472 ? 122.616 132.698 98.018  1.00 240.99 ?  454 LEU A CB  1 
ATOM 3209 C CG  . LEU A 1 472 ? 123.560 133.123 96.899  1.00 240.99 ?  454 LEU A CG  1 
ATOM 3210 C CD1 . LEU A 1 472 ? 124.947 132.572 97.143  1.00 240.99 ?  454 LEU A CD1 1 
ATOM 3211 C CD2 . LEU A 1 472 ? 123.029 132.642 95.567  1.00 240.99 ?  454 LEU A CD2 1 
ATOM 3212 N N   . PRO A 1 473 ? 122.577 135.188 100.018 1.00 233.45 ?  455 PRO A N   1 
ATOM 3213 C CA  . PRO A 1 473 ? 122.983 136.574 100.287 1.00 233.45 ?  455 PRO A CA  1 
ATOM 3214 C C   . PRO A 1 473 ? 124.099 136.666 101.300 1.00 233.45 ?  455 PRO A C   1 
ATOM 3215 O O   . PRO A 1 473 ? 125.077 137.386 101.080 1.00 233.45 ?  455 PRO A O   1 
ATOM 3216 C CB  . PRO A 1 473 ? 121.690 137.215 100.797 1.00 233.45 ?  455 PRO A CB  1 
ATOM 3217 C CG  . PRO A 1 473 ? 120.631 136.473 100.100 1.00 233.45 ?  455 PRO A CG  1 
ATOM 3218 C CD  . PRO A 1 473 ? 121.110 135.057 100.011 1.00 233.45 ?  455 PRO A CD  1 
ATOM 3219 N N   . PHE A 1 474 ? 123.991 135.923 102.398 1.00 249.40 ?  456 PHE A N   1 
ATOM 3220 C CA  . PHE A 1 474 ? 125.074 135.892 103.369 1.00 249.40 ?  456 PHE A CA  1 
ATOM 3221 C C   . PHE A 1 474 ? 126.354 135.373 102.742 1.00 249.40 ?  456 PHE A C   1 
ATOM 3222 O O   . PHE A 1 474 ? 127.439 135.909 102.996 1.00 249.40 ?  456 PHE A O   1 
ATOM 3223 C CB  . PHE A 1 474 ? 124.675 135.028 104.556 1.00 249.40 ?  456 PHE A CB  1 
ATOM 3224 C CG  . PHE A 1 474 ? 123.541 135.589 105.340 1.00 249.40 ?  456 PHE A CG  1 
ATOM 3225 C CD1 . PHE A 1 474 ? 123.767 136.523 106.334 1.00 249.40 ?  456 PHE A CD1 1 
ATOM 3226 C CD2 . PHE A 1 474 ? 122.242 135.204 105.066 1.00 249.40 ?  456 PHE A CD2 1 
ATOM 3227 C CE1 . PHE A 1 474 ? 122.720 137.050 107.056 1.00 249.40 ?  456 PHE A CE1 1 
ATOM 3228 C CE2 . PHE A 1 474 ? 121.189 135.728 105.785 1.00 249.40 ?  456 PHE A CE2 1 
ATOM 3229 C CZ  . PHE A 1 474 ? 121.428 136.654 106.782 1.00 249.40 ?  456 PHE A CZ  1 
ATOM 3230 N N   . TYR A 1 475 ? 126.246 134.318 101.935 1.00 239.73 ?  457 TYR A N   1 
ATOM 3231 C CA  . TYR A 1 475 ? 127.416 133.789 101.248 1.00 239.73 ?  457 TYR A CA  1 
ATOM 3232 C C   . TYR A 1 475 ? 128.177 134.904 100.562 1.00 239.73 ?  457 TYR A C   1 
ATOM 3233 O O   . TYR A 1 475 ? 129.338 135.176 100.881 1.00 239.73 ?  457 TYR A O   1 
ATOM 3234 C CB  . TYR A 1 475 ? 126.998 132.743 100.224 1.00 239.73 ?  457 TYR A CB  1 
ATOM 3235 C CG  . TYR A 1 475 ? 128.086 132.410 99.241  1.00 239.73 ?  457 TYR A CG  1 
ATOM 3236 C CD1 . TYR A 1 475 ? 129.024 131.443 99.536  1.00 239.73 ?  457 TYR A CD1 1 
ATOM 3237 C CD2 . TYR A 1 475 ? 128.177 133.061 98.019  1.00 239.73 ?  457 TYR A CD2 1 
ATOM 3238 C CE1 . TYR A 1 475 ? 130.013 131.127 98.647  1.00 239.73 ?  457 TYR A CE1 1 
ATOM 3239 C CE2 . TYR A 1 475 ? 129.168 132.756 97.126  1.00 239.73 ?  457 TYR A CE2 1 
ATOM 3240 C CZ  . TYR A 1 475 ? 130.087 131.790 97.444  1.00 239.73 ?  457 TYR A CZ  1 
ATOM 3241 O OH  . TYR A 1 475 ? 131.085 131.470 96.553  1.00 239.73 ?  457 TYR A OH  1 
ATOM 3242 N N   . PHE A 1 476 ? 127.518 135.584 99.632  1.00 254.19 ?  458 PHE A N   1 
ATOM 3243 C CA  . PHE A 1 476 ? 128.214 136.636 98.915  1.00 254.19 ?  458 PHE A CA  1 
ATOM 3244 C C   . PHE A 1 476 ? 128.515 137.835 99.790  1.00 254.19 ?  458 PHE A C   1 
ATOM 3245 O O   . PHE A 1 476 ? 129.325 138.679 99.398  1.00 254.19 ?  458 PHE A O   1 
ATOM 3246 C CB  . PHE A 1 476 ? 127.411 137.050 97.697  1.00 254.19 ?  458 PHE A CB  1 
ATOM 3247 C CG  . PHE A 1 476 ? 127.682 136.196 96.518  1.00 254.19 ?  458 PHE A CG  1 
ATOM 3248 C CD1 . PHE A 1 476 ? 128.947 136.163 95.965  1.00 254.19 ?  458 PHE A CD1 1 
ATOM 3249 C CD2 . PHE A 1 476 ? 126.697 135.396 95.982  1.00 254.19 ?  458 PHE A CD2 1 
ATOM 3250 C CE1 . PHE A 1 476 ? 129.220 135.366 94.880  1.00 254.19 ?  458 PHE A CE1 1 
ATOM 3251 C CE2 . PHE A 1 476 ? 126.962 134.593 94.895  1.00 254.19 ?  458 PHE A CE2 1 
ATOM 3252 C CZ  . PHE A 1 476 ? 128.226 134.578 94.343  1.00 254.19 ?  458 PHE A CZ  1 
ATOM 3253 N N   . LEU A 1 477 ? 127.894 137.923 100.962 1.00 261.80 ?  459 LEU A N   1 
ATOM 3254 C CA  . LEU A 1 477 ? 128.300 138.936 101.921 1.00 261.80 ?  459 LEU A CA  1 
ATOM 3255 C C   . LEU A 1 477 ? 129.649 138.600 102.537 1.00 261.80 ?  459 LEU A C   1 
ATOM 3256 O O   . LEU A 1 477 ? 130.396 139.504 102.923 1.00 261.80 ?  459 LEU A O   1 
ATOM 3257 C CB  . LEU A 1 477 ? 127.238 139.073 103.009 1.00 261.80 ?  459 LEU A CB  1 
ATOM 3258 C CG  . LEU A 1 477 ? 126.085 140.034 102.728 1.00 261.80 ?  459 LEU A CG  1 
ATOM 3259 C CD1 . LEU A 1 477 ? 124.858 139.634 103.531 1.00 261.80 ?  459 LEU A CD1 1 
ATOM 3260 C CD2 . LEU A 1 477 ? 126.494 141.463 103.044 1.00 261.80 ?  459 LEU A CD2 1 
ATOM 3261 N N   . ILE A 1 478 ? 129.984 137.315 102.631 1.00 258.98 ?  460 ILE A N   1 
ATOM 3262 C CA  . ILE A 1 478 ? 131.186 136.922 103.358 1.00 258.98 ?  460 ILE A CA  1 
ATOM 3263 C C   . ILE A 1 478 ? 132.214 136.275 102.439 1.00 258.98 ?  460 ILE A C   1 
ATOM 3264 O O   . ILE A 1 478 ? 133.418 136.496 102.607 1.00 258.98 ?  460 ILE A O   1 
ATOM 3265 C CB  . ILE A 1 478 ? 130.843 135.985 104.532 1.00 258.98 ?  460 ILE A CB  1 
ATOM 3266 C CG1 . ILE A 1 478 ? 132.105 135.633 105.325 1.00 258.98 ?  460 ILE A CG1 1 
ATOM 3267 C CG2 . ILE A 1 478 ? 130.175 134.715 104.036 1.00 258.98 ?  460 ILE A CG2 1 
ATOM 3268 C CD1 . ILE A 1 478 ? 131.832 134.937 106.651 1.00 258.98 ?  460 ILE A CD1 1 
ATOM 3269 N N   . ILE A 1 479 ? 131.751 135.493 101.459 1.00 246.59 ?  461 ILE A N   1 
ATOM 3270 C CA  . ILE A 1 479 ? 132.597 134.535 100.750 1.00 246.59 ?  461 ILE A CA  1 
ATOM 3271 C C   . ILE A 1 479 ? 133.954 135.110 100.373 1.00 246.59 ?  461 ILE A C   1 
ATOM 3272 O O   . ILE A 1 479 ? 134.992 134.519 100.684 1.00 246.59 ?  461 ILE A O   1 
ATOM 3273 C CB  . ILE A 1 479 ? 131.895 133.972 99.503  1.00 246.59 ?  461 ILE A CB  1 
ATOM 3274 C CG1 . ILE A 1 479 ? 132.835 132.984 98.820  1.00 246.59 ?  461 ILE A CG1 1 
ATOM 3275 C CG2 . ILE A 1 479 ? 131.432 135.075 98.555  1.00 246.59 ?  461 ILE A CG2 1 
ATOM 3276 C CD1 . ILE A 1 479 ? 133.171 131.791 99.678  1.00 246.59 ?  461 ILE A CD1 1 
ATOM 3277 N N   . ARG A 1 480 ? 133.956 136.285 99.755  1.00 262.23 ?  462 ARG A N   1 
ATOM 3278 C CA  . ARG A 1 480 ? 135.214 136.953 99.458  1.00 262.23 ?  462 ARG A CA  1 
ATOM 3279 C C   . ARG A 1 480 ? 135.261 138.185 100.336 1.00 262.23 ?  462 ARG A C   1 
ATOM 3280 O O   . ARG A 1 480 ? 135.268 139.310 99.836  1.00 262.23 ?  462 ARG A O   1 
ATOM 3281 C CB  . ARG A 1 480 ? 135.317 137.325 97.984  1.00 262.23 ?  462 ARG A CB  1 
ATOM 3282 C CG  . ARG A 1 480 ? 136.749 137.481 97.499  1.00 262.23 ?  462 ARG A CG  1 
ATOM 3283 C CD  . ARG A 1 480 ? 137.704 136.641 98.333  1.00 262.23 ?  462 ARG A CD  1 
ATOM 3284 N NE  . ARG A 1 480 ? 138.364 137.424 99.374  1.00 262.23 ?  462 ARG A NE  1 
ATOM 3285 C CZ  . ARG A 1 480 ? 138.395 137.084 100.659 1.00 262.23 ?  462 ARG A CZ  1 
ATOM 3286 N NH1 . ARG A 1 480 ? 137.800 135.971 101.067 1.00 262.23 1  462 ARG A NH1 1 
ATOM 3287 N NH2 . ARG A 1 480 ? 139.020 137.856 101.536 1.00 262.23 ?  462 ARG A NH2 1 
ATOM 3288 N N   . VAL A 1 481 ? 135.291 137.984 101.649 1.00 276.02 ?  463 VAL A N   1 
ATOM 3289 C CA  . VAL A 1 481 ? 135.254 139.112 102.579 1.00 276.02 ?  463 VAL A CA  1 
ATOM 3290 C C   . VAL A 1 481 ? 136.290 140.179 102.253 1.00 276.02 ?  463 VAL A C   1 
ATOM 3291 O O   . VAL A 1 481 ? 137.475 139.881 102.112 1.00 276.02 ?  463 VAL A O   1 
ATOM 3292 C CB  . VAL A 1 481 ? 135.449 138.629 104.032 1.00 276.02 ?  463 VAL A CB  1 
ATOM 3293 C CG1 . VAL A 1 481 ? 136.559 137.592 104.103 1.00 276.02 ?  463 VAL A CG1 1 
ATOM 3294 C CG2 . VAL A 1 481 ? 135.729 139.799 104.961 1.00 276.02 ?  463 VAL A CG2 1 
ATOM 3295 N N   . PRO A 1 482 ? 135.843 141.437 102.133 1.00 294.47 ?  464 PRO A N   1 
ATOM 3296 C CA  . PRO A 1 482 ? 136.764 142.537 101.840 1.00 294.47 ?  464 PRO A CA  1 
ATOM 3297 C C   . PRO A 1 482 ? 137.476 143.007 103.096 1.00 294.47 ?  464 PRO A C   1 
ATOM 3298 O O   . PRO A 1 482 ? 138.439 143.768 102.998 1.00 294.47 ?  464 PRO A O   1 
ATOM 3299 C CB  . PRO A 1 482 ? 135.830 143.634 101.338 1.00 294.47 ?  464 PRO A CB  1 
ATOM 3300 C CG  . PRO A 1 482 ? 134.556 143.387 102.073 1.00 294.47 ?  464 PRO A CG  1 
ATOM 3301 C CD  . PRO A 1 482 ? 134.446 141.895 102.240 1.00 294.47 ?  464 PRO A CD  1 
ATOM 3302 N N   . GLU A 1 483 ? 137.005 142.571 104.260 1.00 297.80 ?  465 GLU A N   1 
ATOM 3303 C CA  . GLU A 1 483 ? 137.615 142.978 105.518 1.00 297.80 ?  465 GLU A CA  1 
ATOM 3304 C C   . GLU A 1 483 ? 137.718 144.489 105.573 1.00 297.80 ?  465 GLU A C   1 
ATOM 3305 O O   . GLU A 1 483 ? 138.734 145.031 106.008 1.00 297.80 ?  465 GLU A O   1 
ATOM 3306 C CB  . GLU A 1 483 ? 138.998 142.346 105.676 1.00 297.80 ?  465 GLU A CB  1 
ATOM 3307 C CG  . GLU A 1 483 ? 139.124 140.965 105.055 1.00 297.80 ?  465 GLU A CG  1 
ATOM 3308 C CD  . GLU A 1 483 ? 139.391 139.888 106.086 1.00 297.80 ?  465 GLU A CD  1 
ATOM 3309 O OE1 . GLU A 1 483 ? 140.099 140.173 107.074 1.00 297.80 ?  465 GLU A OE1 1 
ATOM 3310 O OE2 . GLU A 1 483 ? 138.891 138.758 105.911 1.00 297.80 -1 465 GLU A OE2 1 
ATOM 3311 N N   . HIS A 1 484 ? 136.671 145.176 105.131 1.00 303.02 ?  466 HIS A N   1 
ATOM 3312 C CA  . HIS A 1 484 ? 136.705 146.633 105.095 1.00 303.02 ?  466 HIS A CA  1 
ATOM 3313 C C   . HIS A 1 484 ? 135.352 147.244 105.410 1.00 303.02 ?  466 HIS A C   1 
ATOM 3314 O O   . HIS A 1 484 ? 134.335 146.552 105.380 1.00 303.02 ?  466 HIS A O   1 
ATOM 3315 C CB  . HIS A 1 484 ? 137.163 147.110 103.718 1.00 303.02 ?  466 HIS A CB  1 
ATOM 3316 C CG  . HIS A 1 484 ? 136.038 147.519 102.821 1.00 303.02 ?  466 HIS A CG  1 
ATOM 3317 N ND1 . HIS A 1 484 ? 135.009 146.666 102.483 1.00 303.02 ?  466 HIS A ND1 1 
ATOM 3318 C CD2 . HIS A 1 484 ? 135.774 148.692 102.199 1.00 303.02 ?  466 HIS A CD2 1 
ATOM 3319 C CE1 . HIS A 1 484 ? 134.162 147.295 101.688 1.00 303.02 ?  466 HIS A CE1 1 
ATOM 3320 N NE2 . HIS A 1 484 ? 134.603 148.526 101.500 1.00 303.02 ?  466 HIS A NE2 1 
ATOM 3321 N N   . LYS A 1 485 ? 135.337 148.535 105.725 1.00 283.01 ?  467 LYS A N   1 
ATOM 3322 C CA  . LYS A 1 485 ? 134.074 149.229 105.976 1.00 283.01 ?  467 LYS A CA  1 
ATOM 3323 C C   . LYS A 1 485 ? 133.262 148.608 107.099 1.00 283.01 ?  467 LYS A C   1 
ATOM 3324 O O   . LYS A 1 485 ? 133.811 148.008 108.020 1.00 283.01 ?  467 LYS A O   1 
ATOM 3325 C CB  . LYS A 1 485 ? 133.232 149.267 104.697 1.00 283.01 ?  467 LYS A CB  1 
ATOM 3326 C CG  . LYS A 1 485 ? 132.673 150.639 104.365 1.00 283.01 ?  467 LYS A CG  1 
ATOM 3327 C CD  . LYS A 1 485 ? 133.706 151.723 104.616 1.00 283.01 ?  467 LYS A CD  1 
ATOM 3328 C CE  . LYS A 1 485 ? 134.771 151.733 103.531 1.00 283.01 ?  467 LYS A CE  1 
ATOM 3329 N NZ  . LYS A 1 485 ? 134.186 151.507 102.181 1.00 283.01 1  467 LYS A NZ  1 
ATOM 3330 N N   . ARG A 1 486 ? 131.944 148.738 107.013 1.00 280.99 ?  468 ARG A N   1 
ATOM 3331 C CA  . ARG A 1 486 ? 131.076 148.200 108.053 1.00 280.99 ?  468 ARG A CA  1 
ATOM 3332 C C   . ARG A 1 486 ? 131.292 146.704 108.247 1.00 280.99 ?  468 ARG A C   1 
ATOM 3333 O O   . ARG A 1 486 ? 131.358 146.235 109.380 1.00 280.99 ?  468 ARG A O   1 
ATOM 3334 C CB  . ARG A 1 486 ? 129.611 148.489 107.723 1.00 280.99 ?  468 ARG A CB  1 
ATOM 3335 C CG  . ARG A 1 486 ? 129.422 149.546 106.646 1.00 280.99 ?  468 ARG A CG  1 
ATOM 3336 C CD  . ARG A 1 486 ? 129.591 150.949 107.209 1.00 280.99 ?  468 ARG A CD  1 
ATOM 3337 N NE  . ARG A 1 486 ? 130.956 151.443 107.051 1.00 280.99 ?  468 ARG A NE  1 
ATOM 3338 C CZ  . ARG A 1 486 ? 131.815 151.596 108.054 1.00 280.99 ?  468 ARG A CZ  1 
ATOM 3339 N NH1 . ARG A 1 486 ? 131.450 151.294 109.292 1.00 280.99 1  468 ARG A NH1 1 
ATOM 3340 N NH2 . ARG A 1 486 ? 133.038 152.049 107.820 1.00 280.99 ?  468 ARG A NH2 1 
ATOM 3341 N N   . PRO A 1 487 ? 131.421 145.946 107.146 1.00 286.21 ?  469 PRO A N   1 
ATOM 3342 C CA  . PRO A 1 487 ? 131.716 144.530 107.361 1.00 286.21 ?  469 PRO A CA  1 
ATOM 3343 C C   . PRO A 1 487 ? 132.888 144.389 108.309 1.00 286.21 ?  469 PRO A C   1 
ATOM 3344 O O   . PRO A 1 487 ? 132.801 143.633 109.274 1.00 286.21 ?  469 PRO A O   1 
ATOM 3345 C CB  . PRO A 1 487 ? 132.113 144.048 105.969 1.00 286.21 ?  469 PRO A CB  1 
ATOM 3346 C CG  . PRO A 1 487 ? 131.350 144.928 105.040 1.00 286.21 ?  469 PRO A CG  1 
ATOM 3347 C CD  . PRO A 1 487 ? 131.185 146.257 105.724 1.00 286.21 ?  469 PRO A CD  1 
ATOM 3348 N N   . LEU A 1 488 ? 133.963 145.124 108.052 1.00 284.43 ?  470 LEU A N   1 
ATOM 3349 C CA  . LEU A 1 488 ? 135.126 145.079 108.927 1.00 284.43 ?  470 LEU A CA  1 
ATOM 3350 C C   . LEU A 1 488 ? 134.755 145.583 110.316 1.00 284.43 ?  470 LEU A C   1 
ATOM 3351 O O   . LEU A 1 488 ? 135.203 145.036 111.322 1.00 284.43 ?  470 LEU A O   1 
ATOM 3352 C CB  . LEU A 1 488 ? 136.273 145.889 108.319 1.00 284.43 ?  470 LEU A CB  1 
ATOM 3353 C CG  . LEU A 1 488 ? 137.080 146.892 109.142 1.00 284.43 ?  470 LEU A CG  1 
ATOM 3354 C CD1 . LEU A 1 488 ? 138.562 146.680 108.879 1.00 284.43 ?  470 LEU A CD1 1 
ATOM 3355 C CD2 . LEU A 1 488 ? 136.691 148.312 108.772 1.00 284.43 ?  470 LEU A CD2 1 
ATOM 3356 N N   . TYR A 1 489 ? 133.919 146.613 110.378 1.00 297.49 ?  471 TYR A N   1 
ATOM 3357 C CA  . TYR A 1 489 ? 133.476 147.117 111.669 1.00 297.49 ?  471 TYR A CA  1 
ATOM 3358 C C   . TYR A 1 489 ? 132.789 146.006 112.438 1.00 297.49 ?  471 TYR A C   1 
ATOM 3359 O O   . TYR A 1 489 ? 133.100 145.761 113.603 1.00 297.49 ?  471 TYR A O   1 
ATOM 3360 C CB  . TYR A 1 489 ? 132.518 148.289 111.488 1.00 297.49 ?  471 TYR A CB  1 
ATOM 3361 C CG  . TYR A 1 489 ? 133.204 149.621 111.325 1.00 297.49 ?  471 TYR A CG  1 
ATOM 3362 C CD1 . TYR A 1 489 ? 132.850 150.706 112.113 1.00 297.49 ?  471 TYR A CD1 1 
ATOM 3363 C CD2 . TYR A 1 489 ? 134.205 149.795 110.382 1.00 297.49 ?  471 TYR A CD2 1 
ATOM 3364 C CE1 . TYR A 1 489 ? 133.476 151.928 111.967 1.00 297.49 ?  471 TYR A CE1 1 
ATOM 3365 C CE2 . TYR A 1 489 ? 134.838 151.012 110.228 1.00 297.49 ?  471 TYR A CE2 1 
ATOM 3366 C CZ  . TYR A 1 489 ? 134.469 152.075 111.023 1.00 297.49 ?  471 TYR A CZ  1 
ATOM 3367 O OH  . TYR A 1 489 ? 135.095 153.290 110.873 1.00 297.49 ?  471 TYR A OH  1 
ATOM 3368 N N   . LEU A 1 490 ? 131.861 145.319 111.784 1.00 292.20 ?  472 LEU A N   1 
ATOM 3369 C CA  . LEU A 1 490 ? 131.155 144.225 112.433 1.00 292.20 ?  472 LEU A CA  1 
ATOM 3370 C C   . LEU A 1 490 ? 132.129 143.125 112.803 1.00 292.20 ?  472 LEU A C   1 
ATOM 3371 O O   . LEU A 1 490 ? 132.031 142.541 113.878 1.00 292.20 ?  472 LEU A O   1 
ATOM 3372 C CB  . LEU A 1 490 ? 130.068 143.673 111.514 1.00 292.20 ?  472 LEU A CB  1 
ATOM 3373 C CG  . LEU A 1 490 ? 129.188 144.720 110.832 1.00 292.20 ?  472 LEU A CG  1 
ATOM 3374 C CD1 . LEU A 1 490 ? 128.714 144.229 109.473 1.00 292.20 ?  472 LEU A CD1 1 
ATOM 3375 C CD2 . LEU A 1 490 ? 128.010 145.094 111.717 1.00 292.20 ?  472 LEU A CD2 1 
ATOM 3376 N N   . ARG A 1 491 ? 133.079 142.849 111.918 1.00 287.29 ?  473 ARG A N   1 
ATOM 3377 C CA  . ARG A 1 491 ? 134.042 141.786 112.170 1.00 287.29 ?  473 ARG A CA  1 
ATOM 3378 C C   . ARG A 1 491 ? 134.799 142.037 113.467 1.00 287.29 ?  473 ARG A C   1 
ATOM 3379 O O   . ARG A 1 491 ? 135.015 141.113 114.250 1.00 287.29 ?  473 ARG A O   1 
ATOM 3380 C CB  . ARG A 1 491 ? 135.014 141.660 110.998 1.00 287.29 ?  473 ARG A CB  1 
ATOM 3381 C CG  . ARG A 1 491 ? 134.424 140.989 109.768 1.00 287.29 ?  473 ARG A CG  1 
ATOM 3382 C CD  . ARG A 1 491 ? 135.017 141.554 108.486 1.00 287.29 ?  473 ARG A CD  1 
ATOM 3383 N NE  . ARG A 1 491 ? 136.375 142.054 108.682 1.00 287.29 ?  473 ARG A NE  1 
ATOM 3384 C CZ  . ARG A 1 491 ? 137.464 141.295 108.622 1.00 287.29 ?  473 ARG A CZ  1 
ATOM 3385 N NH1 . ARG A 1 491 ? 137.356 139.998 108.370 1.00 287.29 1  473 ARG A NH1 1 
ATOM 3386 N NH2 . ARG A 1 491 ? 138.660 141.832 108.814 1.00 287.29 ?  473 ARG A NH2 1 
ATOM 3387 N N   . ARG A 1 492 ? 135.201 143.281 113.702 1.00 291.66 ?  474 ARG A N   1 
ATOM 3388 C CA  . ARG A 1 492 ? 135.876 143.606 114.953 1.00 291.66 ?  474 ARG A CA  1 
ATOM 3389 C C   . ARG A 1 492 ? 134.943 143.289 116.110 1.00 291.66 ?  474 ARG A C   1 
ATOM 3390 O O   . ARG A 1 492 ? 135.365 142.711 117.112 1.00 291.66 ?  474 ARG A O   1 
ATOM 3391 C CB  . ARG A 1 492 ? 136.318 145.071 114.971 1.00 291.66 ?  474 ARG A CB  1 
ATOM 3392 C CG  . ARG A 1 492 ? 135.440 146.004 115.788 1.00 291.66 ?  474 ARG A CG  1 
ATOM 3393 C CD  . ARG A 1 492 ? 135.265 147.339 115.085 1.00 291.66 ?  474 ARG A CD  1 
ATOM 3394 N NE  . ARG A 1 492 ? 136.019 147.396 113.836 1.00 291.66 ?  474 ARG A NE  1 
ATOM 3395 C CZ  . ARG A 1 492 ? 136.153 148.491 113.095 1.00 291.66 ?  474 ARG A CZ  1 
ATOM 3396 N NH1 . ARG A 1 492 ? 135.582 149.625 113.475 1.00 291.66 1  474 ARG A NH1 1 
ATOM 3397 N NH2 . ARG A 1 492 ? 136.858 148.451 111.975 1.00 291.66 ?  474 ARG A NH2 1 
ATOM 3398 N N   . ILE A 1 493 ? 133.674 143.653 115.974 1.00 278.95 ?  475 ILE A N   1 
ATOM 3399 C CA  . ILE A 1 493 ? 132.690 143.336 117.004 1.00 278.95 ?  475 ILE A CA  1 
ATOM 3400 C C   . ILE A 1 493 ? 132.552 141.831 117.147 1.00 278.95 ?  475 ILE A C   1 
ATOM 3401 O O   . ILE A 1 493 ? 132.585 141.288 118.258 1.00 278.95 ?  475 ILE A O   1 
ATOM 3402 C CB  . ILE A 1 493 ? 131.339 143.995 116.682 1.00 278.95 ?  475 ILE A CB  1 
ATOM 3403 C CG1 . ILE A 1 493 ? 131.442 145.512 116.826 1.00 278.95 ?  475 ILE A CG1 1 
ATOM 3404 C CG2 . ILE A 1 493 ? 130.242 143.441 117.578 1.00 278.95 ?  475 ILE A CG2 1 
ATOM 3405 C CD1 . ILE A 1 493 ? 130.215 146.251 116.319 1.00 278.95 ?  475 ILE A CD1 1 
ATOM 3406 N N   . VAL A 1 494 ? 132.407 141.139 116.015 1.00 264.16 ?  476 VAL A N   1 
ATOM 3407 C CA  . VAL A 1 494 ? 132.424 139.680 116.022 1.00 264.16 ?  476 VAL A CA  1 
ATOM 3408 C C   . VAL A 1 494 ? 133.555 139.179 116.898 1.00 264.16 ?  476 VAL A C   1 
ATOM 3409 O O   . VAL A 1 494 ? 133.340 138.408 117.839 1.00 264.16 ?  476 VAL A O   1 
ATOM 3410 C CB  . VAL A 1 494 ? 132.554 139.137 114.591 1.00 264.16 ?  476 VAL A CB  1 
ATOM 3411 C CG1 . VAL A 1 494 ? 132.666 137.638 114.627 1.00 264.16 ?  476 VAL A CG1 1 
ATOM 3412 C CG2 . VAL A 1 494 ? 131.354 139.540 113.762 1.00 264.16 ?  476 VAL A CG2 1 
ATOM 3413 N N   . GLY A 1 495 ? 134.769 139.643 116.619 1.00 258.96 ?  477 GLY A N   1 
ATOM 3414 C CA  . GLY A 1 495 ? 135.911 139.333 117.450 1.00 258.96 ?  477 GLY A CA  1 
ATOM 3415 C C   . GLY A 1 495 ? 135.582 139.516 118.912 1.00 258.96 ?  477 GLY A C   1 
ATOM 3416 O O   . GLY A 1 495 ? 135.582 138.546 119.676 1.00 258.96 ?  477 GLY A O   1 
ATOM 3417 N N   . SER A 1 496 ? 135.253 140.749 119.301 1.00 259.36 ?  478 SER A N   1 
ATOM 3418 C CA  . SER A 1 496 ? 134.829 140.986 120.674 1.00 259.36 ?  478 SER A CA  1 
ATOM 3419 C C   . SER A 1 496 ? 133.682 140.063 121.044 1.00 259.36 ?  478 SER A C   1 
ATOM 3420 O O   . SER A 1 496 ? 133.722 139.397 122.085 1.00 259.36 ?  478 SER A O   1 
ATOM 3421 C CB  . SER A 1 496 ? 134.417 142.441 120.863 1.00 259.36 ?  478 SER A CB  1 
ATOM 3422 O OG  . SER A 1 496 ? 133.433 142.806 119.918 1.00 259.36 ?  478 SER A OG  1 
ATOM 3423 N N   . ALA A 1 497 ? 132.657 140.001 120.191 1.00 255.18 ?  479 ALA A N   1 
ATOM 3424 C CA  . ALA A 1 497 ? 131.591 139.029 120.387 1.00 255.18 ?  479 ALA A CA  1 
ATOM 3425 C C   . ALA A 1 497 ? 132.171 137.642 120.591 1.00 255.18 ?  479 ALA A C   1 
ATOM 3426 O O   . ALA A 1 497 ? 131.873 136.968 121.584 1.00 255.18 ?  479 ALA A O   1 
ATOM 3427 C CB  . ALA A 1 497 ? 130.641 139.044 119.191 1.00 255.18 ?  479 ALA A CB  1 
ATOM 3428 N N   . THR A 1 498 ? 133.011 137.206 119.654 1.00 244.83 ?  480 THR A N   1 
ATOM 3429 C CA  . THR A 1 498 ? 133.801 136.005 119.864 1.00 244.83 ?  480 THR A CA  1 
ATOM 3430 C C   . THR A 1 498 ? 134.432 136.021 121.242 1.00 244.83 ?  480 THR A C   1 
ATOM 3431 O O   . THR A 1 498 ? 134.130 135.174 122.089 1.00 244.83 ?  480 THR A O   1 
ATOM 3432 C CB  . THR A 1 498 ? 134.878 135.905 118.794 1.00 244.83 ?  480 THR A CB  1 
ATOM 3433 O OG1 . THR A 1 498 ? 134.262 135.916 117.502 1.00 244.83 ?  480 THR A OG1 1 
ATOM 3434 C CG2 . THR A 1 498 ? 135.664 134.630 118.974 1.00 244.83 ?  480 THR A CG2 1 
ATOM 3435 N N   . ARG A 1 499 ? 135.287 137.013 121.489 1.00 252.56 ?  481 ARG A N   1 
ATOM 3436 C CA  . ARG A 1 499 ? 135.859 137.198 122.815 1.00 252.56 ?  481 ARG A CA  1 
ATOM 3437 C C   . ARG A 1 499 ? 134.792 137.036 123.878 1.00 252.56 ?  481 ARG A C   1 
ATOM 3438 O O   . ARG A 1 499 ? 134.938 136.235 124.809 1.00 252.56 ?  481 ARG A O   1 
ATOM 3439 C CB  . ARG A 1 499 ? 136.511 138.575 122.912 1.00 252.56 ?  481 ARG A CB  1 
ATOM 3440 C CG  . ARG A 1 499 ? 137.636 138.784 121.924 1.00 252.56 ?  481 ARG A CG  1 
ATOM 3441 C CD  . ARG A 1 499 ? 138.191 140.193 121.996 1.00 252.56 ?  481 ARG A CD  1 
ATOM 3442 N NE  . ARG A 1 499 ? 139.348 140.355 121.122 1.00 252.56 ?  481 ARG A NE  1 
ATOM 3443 C CZ  . ARG A 1 499 ? 139.921 141.522 120.849 1.00 252.56 ?  481 ARG A CZ  1 
ATOM 3444 N NH1 . ARG A 1 499 ? 139.442 142.638 121.381 1.00 252.56 1  481 ARG A NH1 1 
ATOM 3445 N NH2 . ARG A 1 499 ? 140.972 141.573 120.042 1.00 252.56 ?  481 ARG A NH2 1 
ATOM 3446 N N   . TYR A 1 500 ? 133.685 137.758 123.717 1.00 255.65 ?  482 TYR A N   1 
ATOM 3447 C CA  . TYR A 1 500 ? 132.563 137.623 124.630 1.00 255.65 ?  482 TYR A CA  1 
ATOM 3448 C C   . TYR A 1 500 ? 132.213 136.157 124.821 1.00 255.65 ?  482 TYR A C   1 
ATOM 3449 O O   . TYR A 1 500 ? 132.470 135.578 125.881 1.00 255.65 ?  482 TYR A O   1 
ATOM 3450 C CB  . TYR A 1 500 ? 131.378 138.409 124.074 1.00 255.65 ?  482 TYR A CB  1 
ATOM 3451 C CG  . TYR A 1 500 ? 130.304 138.747 125.075 1.00 255.65 ?  482 TYR A CG  1 
ATOM 3452 C CD1 . TYR A 1 500 ? 130.601 139.468 126.222 1.00 255.65 ?  482 TYR A CD1 1 
ATOM 3453 C CD2 . TYR A 1 500 ? 128.983 138.389 124.849 1.00 255.65 ?  482 TYR A CD2 1 
ATOM 3454 C CE1 . TYR A 1 500 ? 129.615 139.795 127.134 1.00 255.65 ?  482 TYR A CE1 1 
ATOM 3455 C CE2 . TYR A 1 500 ? 127.991 138.712 125.751 1.00 255.65 ?  482 TYR A CE2 1 
ATOM 3456 C CZ  . TYR A 1 500 ? 128.312 139.415 126.892 1.00 255.65 ?  482 TYR A CZ  1 
ATOM 3457 O OH  . TYR A 1 500 ? 127.326 139.740 127.794 1.00 255.65 ?  482 TYR A OH  1 
ATOM 3458 N N   . LEU A 1 501 ? 131.741 135.507 123.758 1.00 241.64 ?  483 LEU A N   1 
ATOM 3459 C CA  . LEU A 1 501 ? 131.357 134.110 123.895 1.00 241.64 ?  483 LEU A CA  1 
ATOM 3460 C C   . LEU A 1 501 ? 132.537 133.278 124.352 1.00 241.64 ?  483 LEU A C   1 
ATOM 3461 O O   . LEU A 1 501 ? 132.367 132.290 125.075 1.00 241.64 ?  483 LEU A O   1 
ATOM 3462 C CB  . LEU A 1 501 ? 130.788 133.575 122.584 1.00 241.64 ?  483 LEU A CB  1 
ATOM 3463 C CG  . LEU A 1 501 ? 131.629 133.739 121.324 1.00 241.64 ?  483 LEU A CG  1 
ATOM 3464 C CD1 . LEU A 1 501 ? 132.537 132.544 121.086 1.00 241.64 ?  483 LEU A CD1 1 
ATOM 3465 C CD2 . LEU A 1 501 ? 130.747 133.997 120.119 1.00 241.64 ?  483 LEU A CD2 1 
ATOM 3466 N N   . GLN A 1 502 ? 133.747 133.692 123.970 1.00 241.03 ?  484 GLN A N   1 
ATOM 3467 C CA  . GLN A 1 502 ? 134.938 133.012 124.452 1.00 241.03 ?  484 GLN A CA  1 
ATOM 3468 C C   . GLN A 1 502 ? 134.884 132.855 125.960 1.00 241.03 ?  484 GLN A C   1 
ATOM 3469 O O   . GLN A 1 502 ? 134.806 131.734 126.478 1.00 241.03 ?  484 GLN A O   1 
ATOM 3470 C CB  . GLN A 1 502 ? 136.190 133.783 124.038 1.00 241.03 ?  484 GLN A CB  1 
ATOM 3471 C CG  . GLN A 1 502 ? 136.638 133.538 122.610 1.00 241.03 ?  484 GLN A CG  1 
ATOM 3472 C CD  . GLN A 1 502 ? 137.837 134.387 122.224 1.00 241.03 ?  484 GLN A CD  1 
ATOM 3473 O OE1 . GLN A 1 502 ? 138.293 135.225 123.000 1.00 241.03 ?  484 GLN A OE1 1 
ATOM 3474 N NE2 . GLN A 1 502 ? 138.350 134.176 121.018 1.00 241.03 ?  484 GLN A NE2 1 
ATOM 3475 N N   . VAL A 1 503 ? 134.857 133.974 126.685 1.00 239.02 ?  485 VAL A N   1 
ATOM 3476 C CA  . VAL A 1 503 ? 134.863 133.848 128.135 1.00 239.02 ?  485 VAL A CA  1 
ATOM 3477 C C   . VAL A 1 503 ? 133.606 133.132 128.583 1.00 239.02 ?  485 VAL A C   1 
ATOM 3478 O O   . VAL A 1 503 ? 133.618 132.395 129.576 1.00 239.02 ?  485 VAL A O   1 
ATOM 3479 C CB  . VAL A 1 503 ? 135.019 135.221 128.816 1.00 239.02 ?  485 VAL A CB  1 
ATOM 3480 C CG1 . VAL A 1 503 ? 133.918 136.173 128.401 1.00 239.02 ?  485 VAL A CG1 1 
ATOM 3481 C CG2 . VAL A 1 503 ? 135.047 135.064 130.327 1.00 239.02 ?  485 VAL A CG2 1 
ATOM 3482 N N   . LEU A 1 504 ? 132.521 133.284 127.831 1.00 236.90 ?  486 LEU A N   1 
ATOM 3483 C CA  . LEU A 1 504 ? 131.301 132.576 128.176 1.00 236.90 ?  486 LEU A CA  1 
ATOM 3484 C C   . LEU A 1 504 ? 131.456 131.087 127.929 1.00 236.90 ?  486 LEU A C   1 
ATOM 3485 O O   . LEU A 1 504 ? 131.056 130.266 128.760 1.00 236.90 ?  486 LEU A O   1 
ATOM 3486 C CB  . LEU A 1 504 ? 130.130 133.143 127.381 1.00 236.90 ?  486 LEU A CB  1 
ATOM 3487 C CG  . LEU A 1 504 ? 130.033 134.663 127.483 1.00 236.90 ?  486 LEU A CG  1 
ATOM 3488 C CD1 . LEU A 1 504 ? 129.121 135.241 126.416 1.00 236.90 ?  486 LEU A CD1 1 
ATOM 3489 C CD2 . LEU A 1 504 ? 129.567 135.061 128.870 1.00 236.90 ?  486 LEU A CD2 1 
ATOM 3490 N N   . CYS A 1 505 ? 132.057 130.716 126.805 1.00 241.42 ?  487 CYS A N   1 
ATOM 3491 C CA  . CYS A 1 505 ? 132.055 129.307 126.457 1.00 241.42 ?  487 CYS A CA  1 
ATOM 3492 C C   . CYS A 1 505 ? 133.029 128.501 127.293 1.00 241.42 ?  487 CYS A C   1 
ATOM 3493 O O   . CYS A 1 505 ? 132.951 127.270 127.284 1.00 241.42 ?  487 CYS A O   1 
ATOM 3494 C CB  . CYS A 1 505 ? 132.386 129.117 124.981 1.00 241.42 ?  487 CYS A CB  1 
ATOM 3495 S SG  . CYS A 1 505 ? 134.036 129.654 124.522 1.00 241.42 ?  487 CYS A SG  1 
ATOM 3496 N N   . MET A 1 506 ? 133.932 129.160 128.017 1.00 240.56 ?  488 MET A N   1 
ATOM 3497 C CA  . MET A 1 506 ? 135.003 128.464 128.719 1.00 240.56 ?  488 MET A CA  1 
ATOM 3498 C C   . MET A 1 506 ? 135.742 127.523 127.776 1.00 240.56 ?  488 MET A C   1 
ATOM 3499 O O   . MET A 1 506 ? 136.133 126.418 128.157 1.00 240.56 ?  488 MET A O   1 
ATOM 3500 C CB  . MET A 1 506 ? 134.468 127.699 129.932 1.00 240.56 ?  488 MET A CB  1 
ATOM 3501 C CG  . MET A 1 506 ? 135.441 127.609 131.086 1.00 240.56 ?  488 MET A CG  1 
ATOM 3502 S SD  . MET A 1 506 ? 134.902 126.452 132.357 1.00 240.56 ?  488 MET A SD  1 
ATOM 3503 C CE  . MET A 1 506 ? 133.284 127.103 132.756 1.00 240.56 ?  488 MET A CE  1 
ATOM 3504 N N   . SER A 1 507 ? 135.915 127.950 126.529 1.00 218.19 ?  489 SER A N   1 
ATOM 3505 C CA  . SER A 1 507 ? 136.461 127.104 125.484 1.00 218.19 ?  489 SER A CA  1 
ATOM 3506 C C   . SER A 1 507 ? 137.275 127.931 124.503 1.00 218.19 ?  489 SER A C   1 
ATOM 3507 O O   . SER A 1 507 ? 137.079 129.141 124.369 1.00 218.19 ?  489 SER A O   1 
ATOM 3508 C CB  . SER A 1 507 ? 135.356 126.379 124.733 1.00 218.19 ?  489 SER A CB  1 
ATOM 3509 O OG  . SER A 1 507 ? 135.804 126.025 123.442 1.00 218.19 ?  489 SER A OG  1 
ATOM 3510 N N   . VAL A 1 508 ? 138.206 127.262 123.822 1.00 208.55 ?  490 VAL A N   1 
ATOM 3511 C CA  . VAL A 1 508 ? 139.041 127.880 122.803 1.00 208.55 ?  490 VAL A CA  1 
ATOM 3512 C C   . VAL A 1 508 ? 139.159 126.902 121.640 1.00 208.55 ?  490 VAL A C   1 
ATOM 3513 O O   . VAL A 1 508 ? 138.741 125.745 121.724 1.00 208.55 ?  490 VAL A O   1 
ATOM 3514 C CB  . VAL A 1 508 ? 140.441 128.276 123.336 1.00 208.55 ?  490 VAL A CB  1 
ATOM 3515 C CG1 . VAL A 1 508 ? 141.125 129.278 122.409 1.00 208.55 ?  490 VAL A CG1 1 
ATOM 3516 C CG2 . VAL A 1 508 ? 140.348 128.855 124.735 1.00 208.55 ?  490 VAL A CG2 1 
ATOM 3517 N N   . ALA A 1 509 ? 139.715 127.392 120.535 1.00 203.38 ?  491 ALA A N   1 
ATOM 3518 C CA  . ALA A 1 509 ? 139.904 126.585 119.344 1.00 203.38 ?  491 ALA A CA  1 
ATOM 3519 C C   . ALA A 1 509 ? 140.967 125.514 119.579 1.00 203.38 ?  491 ALA A C   1 
ATOM 3520 O O   . ALA A 1 509 ? 141.610 125.450 120.626 1.00 203.38 ?  491 ALA A O   1 
ATOM 3521 C CB  . ALA A 1 509 ? 140.301 127.465 118.162 1.00 203.38 ?  491 ALA A CB  1 
ATOM 3522 N N   . ALA A 1 510 ? 141.149 124.669 118.570 1.00 223.90 ?  492 ALA A N   1 
ATOM 3523 C CA  . ALA A 1 510 ? 142.104 123.570 118.646 1.00 223.90 ?  492 ALA A CA  1 
ATOM 3524 C C   . ALA A 1 510 ? 143.519 124.049 118.362 1.00 223.90 ?  492 ALA A C   1 
ATOM 3525 O O   . ALA A 1 510 ? 143.789 125.249 118.364 1.00 223.90 ?  492 ALA A O   1 
ATOM 3526 C CB  . ALA A 1 510 ? 141.718 122.467 117.677 1.00 223.90 ?  492 ALA A CB  1 
# 
