data_8KDZ
# 
_entry.id   8KDZ 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8KDZ         pdb_00008kdz 10.2210/pdb8kdz/pdb 
WWPDB D_1300040217 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-02-19 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8KDZ 
_pdbx_database_status.recvd_initial_deposition_date   2023-08-10 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              SHAILLY.TOMAR@BT.IITR.AC.IN 
_pdbx_contact_author.name_first         SHAILLY 
_pdbx_contact_author.name_last          TOMAR 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1730-003X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Bhutkar, M.' 1 0000-0001-7990-7825 
'Kumar, A.'   2 0000-0002-7847-0067 
'Tomar, S.'   3 0000-0002-1730-003X 
'Kumar, P.'   4 0000-0003-2128-7736 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
;Deciphering Antiviral Mechanisms of Herbacetin and Caffeic acid phenethyl ester against Chikungunya and Dengue virus, with insights into Dengue methyltransferase-CAPE crystal structure
;
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Bhutkar, M.' 1 0000-0001-7990-7825 
primary 'Kumar, A.'   2 0000-0002-7847-0067 
primary 'Tomar, S.'   3 0000-0002-1730-003X 
primary 'Kumar, P.'   4 0000-0003-2128-7736 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man methyltransferase                                         32107.812 2   ? ? ? ? 
2 non-polymer syn S-ADENOSYL-L-HOMOCYSTEINE                                 384.411   2   ? ? ? ? 
3 non-polymer syn '2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate' 284.307   2   ? ? ? ? 
4 water       nat water                                                     18.015    124 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Genome polyprotein' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;HHHHHHSSGLVPRGSHMASGTGSQGETLGEKWKKKLNQLSRKEFDLYKKSGITEVDRTEAKEGLKRGETTHHAVSRGSAK
LQWFVERNMVIPEGRVIDLGCGRGGWSYYCAGLKKVTEVRGYTKGGPGHEEPVPMSTYGWNIVKLMSGKDVFYLPPEKCD
TLLCDIGESSPSPTVEESRTIRVLKMVEPWLKNNQFCIKVLNPYMPTVIEHLERLQRKHGGMLVRNPLSRNSTHEMYWIS
NGTGNIVSSVNMVSRLLLNRFTMTHRRPTIEKDVDLGAGTRHVN
;
_entity_poly.pdbx_seq_one_letter_code_can   
;HHHHHHSSGLVPRGSHMASGTGSQGETLGEKWKKKLNQLSRKEFDLYKKSGITEVDRTEAKEGLKRGETTHHAVSRGSAK
LQWFVERNMVIPEGRVIDLGCGRGGWSYYCAGLKKVTEVRGYTKGGPGHEEPVPMSTYGWNIVKLMSGKDVFYLPPEKCD
TLLCDIGESSPSPTVEESRTIRVLKMVEPWLKNNQFCIKVLNPYMPTVIEHLERLQRKHGGMLVRNPLSRNSTHEMYWIS
NGTGNIVSSVNMVSRLLLNRFTMTHRRPTIEKDVDLGAGTRHVN
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 S-ADENOSYL-L-HOMOCYSTEINE                                 SAH 
3 '2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate' QAP 
4 water                                                     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   HIS n 
1 2   HIS n 
1 3   HIS n 
1 4   HIS n 
1 5   HIS n 
1 6   HIS n 
1 7   SER n 
1 8   SER n 
1 9   GLY n 
1 10  LEU n 
1 11  VAL n 
1 12  PRO n 
1 13  ARG n 
1 14  GLY n 
1 15  SER n 
1 16  HIS n 
1 17  MET n 
1 18  ALA n 
1 19  SER n 
1 20  GLY n 
1 21  THR n 
1 22  GLY n 
1 23  SER n 
1 24  GLN n 
1 25  GLY n 
1 26  GLU n 
1 27  THR n 
1 28  LEU n 
1 29  GLY n 
1 30  GLU n 
1 31  LYS n 
1 32  TRP n 
1 33  LYS n 
1 34  LYS n 
1 35  LYS n 
1 36  LEU n 
1 37  ASN n 
1 38  GLN n 
1 39  LEU n 
1 40  SER n 
1 41  ARG n 
1 42  LYS n 
1 43  GLU n 
1 44  PHE n 
1 45  ASP n 
1 46  LEU n 
1 47  TYR n 
1 48  LYS n 
1 49  LYS n 
1 50  SER n 
1 51  GLY n 
1 52  ILE n 
1 53  THR n 
1 54  GLU n 
1 55  VAL n 
1 56  ASP n 
1 57  ARG n 
1 58  THR n 
1 59  GLU n 
1 60  ALA n 
1 61  LYS n 
1 62  GLU n 
1 63  GLY n 
1 64  LEU n 
1 65  LYS n 
1 66  ARG n 
1 67  GLY n 
1 68  GLU n 
1 69  THR n 
1 70  THR n 
1 71  HIS n 
1 72  HIS n 
1 73  ALA n 
1 74  VAL n 
1 75  SER n 
1 76  ARG n 
1 77  GLY n 
1 78  SER n 
1 79  ALA n 
1 80  LYS n 
1 81  LEU n 
1 82  GLN n 
1 83  TRP n 
1 84  PHE n 
1 85  VAL n 
1 86  GLU n 
1 87  ARG n 
1 88  ASN n 
1 89  MET n 
1 90  VAL n 
1 91  ILE n 
1 92  PRO n 
1 93  GLU n 
1 94  GLY n 
1 95  ARG n 
1 96  VAL n 
1 97  ILE n 
1 98  ASP n 
1 99  LEU n 
1 100 GLY n 
1 101 CYS n 
1 102 GLY n 
1 103 ARG n 
1 104 GLY n 
1 105 GLY n 
1 106 TRP n 
1 107 SER n 
1 108 TYR n 
1 109 TYR n 
1 110 CYS n 
1 111 ALA n 
1 112 GLY n 
1 113 LEU n 
1 114 LYS n 
1 115 LYS n 
1 116 VAL n 
1 117 THR n 
1 118 GLU n 
1 119 VAL n 
1 120 ARG n 
1 121 GLY n 
1 122 TYR n 
1 123 THR n 
1 124 LYS n 
1 125 GLY n 
1 126 GLY n 
1 127 PRO n 
1 128 GLY n 
1 129 HIS n 
1 130 GLU n 
1 131 GLU n 
1 132 PRO n 
1 133 VAL n 
1 134 PRO n 
1 135 MET n 
1 136 SER n 
1 137 THR n 
1 138 TYR n 
1 139 GLY n 
1 140 TRP n 
1 141 ASN n 
1 142 ILE n 
1 143 VAL n 
1 144 LYS n 
1 145 LEU n 
1 146 MET n 
1 147 SER n 
1 148 GLY n 
1 149 LYS n 
1 150 ASP n 
1 151 VAL n 
1 152 PHE n 
1 153 TYR n 
1 154 LEU n 
1 155 PRO n 
1 156 PRO n 
1 157 GLU n 
1 158 LYS n 
1 159 CYS n 
1 160 ASP n 
1 161 THR n 
1 162 LEU n 
1 163 LEU n 
1 164 CYS n 
1 165 ASP n 
1 166 ILE n 
1 167 GLY n 
1 168 GLU n 
1 169 SER n 
1 170 SER n 
1 171 PRO n 
1 172 SER n 
1 173 PRO n 
1 174 THR n 
1 175 VAL n 
1 176 GLU n 
1 177 GLU n 
1 178 SER n 
1 179 ARG n 
1 180 THR n 
1 181 ILE n 
1 182 ARG n 
1 183 VAL n 
1 184 LEU n 
1 185 LYS n 
1 186 MET n 
1 187 VAL n 
1 188 GLU n 
1 189 PRO n 
1 190 TRP n 
1 191 LEU n 
1 192 LYS n 
1 193 ASN n 
1 194 ASN n 
1 195 GLN n 
1 196 PHE n 
1 197 CYS n 
1 198 ILE n 
1 199 LYS n 
1 200 VAL n 
1 201 LEU n 
1 202 ASN n 
1 203 PRO n 
1 204 TYR n 
1 205 MET n 
1 206 PRO n 
1 207 THR n 
1 208 VAL n 
1 209 ILE n 
1 210 GLU n 
1 211 HIS n 
1 212 LEU n 
1 213 GLU n 
1 214 ARG n 
1 215 LEU n 
1 216 GLN n 
1 217 ARG n 
1 218 LYS n 
1 219 HIS n 
1 220 GLY n 
1 221 GLY n 
1 222 MET n 
1 223 LEU n 
1 224 VAL n 
1 225 ARG n 
1 226 ASN n 
1 227 PRO n 
1 228 LEU n 
1 229 SER n 
1 230 ARG n 
1 231 ASN n 
1 232 SER n 
1 233 THR n 
1 234 HIS n 
1 235 GLU n 
1 236 MET n 
1 237 TYR n 
1 238 TRP n 
1 239 ILE n 
1 240 SER n 
1 241 ASN n 
1 242 GLY n 
1 243 THR n 
1 244 GLY n 
1 245 ASN n 
1 246 ILE n 
1 247 VAL n 
1 248 SER n 
1 249 SER n 
1 250 VAL n 
1 251 ASN n 
1 252 MET n 
1 253 VAL n 
1 254 SER n 
1 255 ARG n 
1 256 LEU n 
1 257 LEU n 
1 258 LEU n 
1 259 ASN n 
1 260 ARG n 
1 261 PHE n 
1 262 THR n 
1 263 MET n 
1 264 THR n 
1 265 HIS n 
1 266 ARG n 
1 267 ARG n 
1 268 PRO n 
1 269 THR n 
1 270 ILE n 
1 271 GLU n 
1 272 LYS n 
1 273 ASP n 
1 274 VAL n 
1 275 ASP n 
1 276 LEU n 
1 277 GLY n 
1 278 ALA n 
1 279 GLY n 
1 280 THR n 
1 281 ARG n 
1 282 HIS n 
1 283 VAL n 
1 284 ASN n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   284 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'dengue virus type 3' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     11069 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     511693 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                                   ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                                                  ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                                                ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                           ? 'C4 H7 N O4'      133.103 
CYS 'L-peptide linking' y CYSTEINE                                                  ? 'C3 H7 N O2 S'    121.158 
GLN 'L-peptide linking' y GLUTAMINE                                                 ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                           ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                                                   ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                                                 ? 'C6 H10 N3 O2 1'  156.162 
HOH non-polymer         . WATER                                                     ? 'H2 O'            18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                                ? 'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                                                   ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                                                    ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                                                ? 'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                             ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                                                   ? 'C5 H9 N O2'      115.130 
QAP non-polymer         . '2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate' ? 'C17 H16 O4'      284.307 
SAH non-polymer         . S-ADENOSYL-L-HOMOCYSTEINE                                 ? 'C14 H20 N6 O5 S' 384.411 
SER 'L-peptide linking' y SERINE                                                    ? 'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                                                 ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                                ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                                                  ? 'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE                                                    ? 'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   HIS 1   -18 ?   ?   ?   A . n 
A 1 2   HIS 2   -17 ?   ?   ?   A . n 
A 1 3   HIS 3   -16 ?   ?   ?   A . n 
A 1 4   HIS 4   -15 ?   ?   ?   A . n 
A 1 5   HIS 5   -14 ?   ?   ?   A . n 
A 1 6   HIS 6   -13 ?   ?   ?   A . n 
A 1 7   SER 7   -12 ?   ?   ?   A . n 
A 1 8   SER 8   -11 ?   ?   ?   A . n 
A 1 9   GLY 9   -10 ?   ?   ?   A . n 
A 1 10  LEU 10  -9  ?   ?   ?   A . n 
A 1 11  VAL 11  -8  ?   ?   ?   A . n 
A 1 12  PRO 12  -7  ?   ?   ?   A . n 
A 1 13  ARG 13  -6  ?   ?   ?   A . n 
A 1 14  GLY 14  -5  ?   ?   ?   A . n 
A 1 15  SER 15  -4  ?   ?   ?   A . n 
A 1 16  HIS 16  -3  ?   ?   ?   A . n 
A 1 17  MET 17  -2  ?   ?   ?   A . n 
A 1 18  ALA 18  -1  ?   ?   ?   A . n 
A 1 19  SER 19  0   ?   ?   ?   A . n 
A 1 20  GLY 20  1   ?   ?   ?   A . n 
A 1 21  THR 21  2   ?   ?   ?   A . n 
A 1 22  GLY 22  3   ?   ?   ?   A . n 
A 1 23  SER 23  4   ?   ?   ?   A . n 
A 1 24  GLN 24  5   ?   ?   ?   A . n 
A 1 25  GLY 25  6   ?   ?   ?   A . n 
A 1 26  GLU 26  7   7   GLU GLU A . n 
A 1 27  THR 27  8   8   THR THR A . n 
A 1 28  LEU 28  9   9   LEU LEU A . n 
A 1 29  GLY 29  10  10  GLY GLY A . n 
A 1 30  GLU 30  11  11  GLU GLU A . n 
A 1 31  LYS 31  12  12  LYS LYS A . n 
A 1 32  TRP 32  13  13  TRP TRP A . n 
A 1 33  LYS 33  14  14  LYS LYS A . n 
A 1 34  LYS 34  15  15  LYS LYS A . n 
A 1 35  LYS 35  16  16  LYS LYS A . n 
A 1 36  LEU 36  17  17  LEU LEU A . n 
A 1 37  ASN 37  18  18  ASN ASN A . n 
A 1 38  GLN 38  19  19  GLN GLN A . n 
A 1 39  LEU 39  20  20  LEU LEU A . n 
A 1 40  SER 40  21  21  SER SER A . n 
A 1 41  ARG 41  22  22  ARG ARG A . n 
A 1 42  LYS 42  23  23  LYS LYS A . n 
A 1 43  GLU 43  24  24  GLU GLU A . n 
A 1 44  PHE 44  25  25  PHE PHE A . n 
A 1 45  ASP 45  26  26  ASP ASP A . n 
A 1 46  LEU 46  27  27  LEU LEU A . n 
A 1 47  TYR 47  28  28  TYR TYR A . n 
A 1 48  LYS 48  29  29  LYS LYS A . n 
A 1 49  LYS 49  30  30  LYS LYS A . n 
A 1 50  SER 50  31  31  SER SER A . n 
A 1 51  GLY 51  32  32  GLY GLY A . n 
A 1 52  ILE 52  33  33  ILE ILE A . n 
A 1 53  THR 53  34  34  THR THR A . n 
A 1 54  GLU 54  35  35  GLU GLU A . n 
A 1 55  VAL 55  36  36  VAL VAL A . n 
A 1 56  ASP 56  37  37  ASP ASP A . n 
A 1 57  ARG 57  38  38  ARG ARG A . n 
A 1 58  THR 58  39  39  THR THR A . n 
A 1 59  GLU 59  40  40  GLU GLU A . n 
A 1 60  ALA 60  41  41  ALA ALA A . n 
A 1 61  LYS 61  42  42  LYS LYS A . n 
A 1 62  GLU 62  43  43  GLU GLU A . n 
A 1 63  GLY 63  44  44  GLY GLY A . n 
A 1 64  LEU 64  45  45  LEU LEU A . n 
A 1 65  LYS 65  46  46  LYS LYS A . n 
A 1 66  ARG 66  47  47  ARG ARG A . n 
A 1 67  GLY 67  48  48  GLY GLY A . n 
A 1 68  GLU 68  49  49  GLU GLU A . n 
A 1 69  THR 69  50  50  THR THR A . n 
A 1 70  THR 70  51  51  THR THR A . n 
A 1 71  HIS 71  52  52  HIS HIS A . n 
A 1 72  HIS 72  53  53  HIS HIS A . n 
A 1 73  ALA 73  54  54  ALA ALA A . n 
A 1 74  VAL 74  55  55  VAL VAL A . n 
A 1 75  SER 75  56  56  SER SER A . n 
A 1 76  ARG 76  57  57  ARG ARG A . n 
A 1 77  GLY 77  58  58  GLY GLY A . n 
A 1 78  SER 78  59  59  SER SER A . n 
A 1 79  ALA 79  60  60  ALA ALA A . n 
A 1 80  LYS 80  61  61  LYS LYS A . n 
A 1 81  LEU 81  62  62  LEU LEU A . n 
A 1 82  GLN 82  63  63  GLN GLN A . n 
A 1 83  TRP 83  64  64  TRP TRP A . n 
A 1 84  PHE 84  65  65  PHE PHE A . n 
A 1 85  VAL 85  66  66  VAL VAL A . n 
A 1 86  GLU 86  67  67  GLU GLU A . n 
A 1 87  ARG 87  68  68  ARG ARG A . n 
A 1 88  ASN 88  69  69  ASN ASN A . n 
A 1 89  MET 89  70  70  MET MET A . n 
A 1 90  VAL 90  71  71  VAL VAL A . n 
A 1 91  ILE 91  72  72  ILE ILE A . n 
A 1 92  PRO 92  73  73  PRO PRO A . n 
A 1 93  GLU 93  74  74  GLU GLU A . n 
A 1 94  GLY 94  75  75  GLY GLY A . n 
A 1 95  ARG 95  76  76  ARG ARG A . n 
A 1 96  VAL 96  77  77  VAL VAL A . n 
A 1 97  ILE 97  78  78  ILE ILE A . n 
A 1 98  ASP 98  79  79  ASP ASP A . n 
A 1 99  LEU 99  80  80  LEU LEU A . n 
A 1 100 GLY 100 81  81  GLY GLY A . n 
A 1 101 CYS 101 82  82  CYS CYS A . n 
A 1 102 GLY 102 83  83  GLY GLY A . n 
A 1 103 ARG 103 84  84  ARG ARG A . n 
A 1 104 GLY 104 85  85  GLY GLY A . n 
A 1 105 GLY 105 86  86  GLY GLY A . n 
A 1 106 TRP 106 87  87  TRP TRP A . n 
A 1 107 SER 107 88  88  SER SER A . n 
A 1 108 TYR 108 89  89  TYR TYR A . n 
A 1 109 TYR 109 90  90  TYR TYR A . n 
A 1 110 CYS 110 91  91  CYS CYS A . n 
A 1 111 ALA 111 92  92  ALA ALA A . n 
A 1 112 GLY 112 93  93  GLY GLY A . n 
A 1 113 LEU 113 94  94  LEU LEU A . n 
A 1 114 LYS 114 95  95  LYS LYS A . n 
A 1 115 LYS 115 96  96  LYS LYS A . n 
A 1 116 VAL 116 97  97  VAL VAL A . n 
A 1 117 THR 117 98  98  THR THR A . n 
A 1 118 GLU 118 99  99  GLU GLU A . n 
A 1 119 VAL 119 100 100 VAL VAL A . n 
A 1 120 ARG 120 101 101 ARG ARG A . n 
A 1 121 GLY 121 102 102 GLY GLY A . n 
A 1 122 TYR 122 103 103 TYR TYR A . n 
A 1 123 THR 123 104 104 THR THR A . n 
A 1 124 LYS 124 105 105 LYS LYS A . n 
A 1 125 GLY 125 106 106 GLY GLY A . n 
A 1 126 GLY 126 107 107 GLY GLY A . n 
A 1 127 PRO 127 108 108 PRO PRO A . n 
A 1 128 GLY 128 109 109 GLY GLY A . n 
A 1 129 HIS 129 110 110 HIS HIS A . n 
A 1 130 GLU 130 111 111 GLU GLU A . n 
A 1 131 GLU 131 112 112 GLU GLU A . n 
A 1 132 PRO 132 113 113 PRO PRO A . n 
A 1 133 VAL 133 114 114 VAL VAL A . n 
A 1 134 PRO 134 115 115 PRO PRO A . n 
A 1 135 MET 135 116 116 MET MET A . n 
A 1 136 SER 136 117 117 SER SER A . n 
A 1 137 THR 137 118 118 THR THR A . n 
A 1 138 TYR 138 119 119 TYR TYR A . n 
A 1 139 GLY 139 120 120 GLY GLY A . n 
A 1 140 TRP 140 121 121 TRP TRP A . n 
A 1 141 ASN 141 122 122 ASN ASN A . n 
A 1 142 ILE 142 123 123 ILE ILE A . n 
A 1 143 VAL 143 124 124 VAL VAL A . n 
A 1 144 LYS 144 125 125 LYS LYS A . n 
A 1 145 LEU 145 126 126 LEU LEU A . n 
A 1 146 MET 146 127 127 MET MET A . n 
A 1 147 SER 147 128 128 SER SER A . n 
A 1 148 GLY 148 129 129 GLY GLY A . n 
A 1 149 LYS 149 130 130 LYS LYS A . n 
A 1 150 ASP 150 131 131 ASP ASP A . n 
A 1 151 VAL 151 132 132 VAL VAL A . n 
A 1 152 PHE 152 133 133 PHE PHE A . n 
A 1 153 TYR 153 134 134 TYR TYR A . n 
A 1 154 LEU 154 135 135 LEU LEU A . n 
A 1 155 PRO 155 136 136 PRO PRO A . n 
A 1 156 PRO 156 137 137 PRO PRO A . n 
A 1 157 GLU 157 138 138 GLU GLU A . n 
A 1 158 LYS 158 139 139 LYS LYS A . n 
A 1 159 CYS 159 140 140 CYS CYS A . n 
A 1 160 ASP 160 141 141 ASP ASP A . n 
A 1 161 THR 161 142 142 THR THR A . n 
A 1 162 LEU 162 143 143 LEU LEU A . n 
A 1 163 LEU 163 144 144 LEU LEU A . n 
A 1 164 CYS 164 145 145 CYS CYS A . n 
A 1 165 ASP 165 146 146 ASP ASP A . n 
A 1 166 ILE 166 147 147 ILE ILE A . n 
A 1 167 GLY 167 148 148 GLY GLY A . n 
A 1 168 GLU 168 149 149 GLU GLU A . n 
A 1 169 SER 169 150 150 SER SER A . n 
A 1 170 SER 170 151 151 SER SER A . n 
A 1 171 PRO 171 152 152 PRO PRO A . n 
A 1 172 SER 172 153 153 SER SER A . n 
A 1 173 PRO 173 154 154 PRO PRO A . n 
A 1 174 THR 174 155 155 THR THR A . n 
A 1 175 VAL 175 156 156 VAL VAL A . n 
A 1 176 GLU 176 157 157 GLU GLU A . n 
A 1 177 GLU 177 158 158 GLU GLU A . n 
A 1 178 SER 178 159 159 SER SER A . n 
A 1 179 ARG 179 160 160 ARG ARG A . n 
A 1 180 THR 180 161 161 THR THR A . n 
A 1 181 ILE 181 162 162 ILE ILE A . n 
A 1 182 ARG 182 163 163 ARG ARG A . n 
A 1 183 VAL 183 164 164 VAL VAL A . n 
A 1 184 LEU 184 165 165 LEU LEU A . n 
A 1 185 LYS 185 166 166 LYS LYS A . n 
A 1 186 MET 186 167 167 MET MET A . n 
A 1 187 VAL 187 168 168 VAL VAL A . n 
A 1 188 GLU 188 169 169 GLU GLU A . n 
A 1 189 PRO 189 170 170 PRO PRO A . n 
A 1 190 TRP 190 171 171 TRP TRP A . n 
A 1 191 LEU 191 172 172 LEU LEU A . n 
A 1 192 LYS 192 173 173 LYS LYS A . n 
A 1 193 ASN 193 174 174 ASN ASN A . n 
A 1 194 ASN 194 175 175 ASN ASN A . n 
A 1 195 GLN 195 176 176 GLN GLN A . n 
A 1 196 PHE 196 177 177 PHE PHE A . n 
A 1 197 CYS 197 178 178 CYS CYS A . n 
A 1 198 ILE 198 179 179 ILE ILE A . n 
A 1 199 LYS 199 180 180 LYS LYS A . n 
A 1 200 VAL 200 181 181 VAL VAL A . n 
A 1 201 LEU 201 182 182 LEU LEU A . n 
A 1 202 ASN 202 183 183 ASN ASN A . n 
A 1 203 PRO 203 184 184 PRO PRO A . n 
A 1 204 TYR 204 185 185 TYR TYR A . n 
A 1 205 MET 205 186 186 MET MET A . n 
A 1 206 PRO 206 187 187 PRO PRO A . n 
A 1 207 THR 207 188 188 THR THR A . n 
A 1 208 VAL 208 189 189 VAL VAL A . n 
A 1 209 ILE 209 190 190 ILE ILE A . n 
A 1 210 GLU 210 191 191 GLU GLU A . n 
A 1 211 HIS 211 192 192 HIS HIS A . n 
A 1 212 LEU 212 193 193 LEU LEU A . n 
A 1 213 GLU 213 194 194 GLU GLU A . n 
A 1 214 ARG 214 195 195 ARG ARG A . n 
A 1 215 LEU 215 196 196 LEU LEU A . n 
A 1 216 GLN 216 197 197 GLN GLN A . n 
A 1 217 ARG 217 198 198 ARG ARG A . n 
A 1 218 LYS 218 199 199 LYS LYS A . n 
A 1 219 HIS 219 200 200 HIS HIS A . n 
A 1 220 GLY 220 201 201 GLY GLY A . n 
A 1 221 GLY 221 202 202 GLY GLY A . n 
A 1 222 MET 222 203 203 MET MET A . n 
A 1 223 LEU 223 204 204 LEU LEU A . n 
A 1 224 VAL 224 205 205 VAL VAL A . n 
A 1 225 ARG 225 206 206 ARG ARG A . n 
A 1 226 ASN 226 207 207 ASN ASN A . n 
A 1 227 PRO 227 208 208 PRO PRO A . n 
A 1 228 LEU 228 209 209 LEU LEU A . n 
A 1 229 SER 229 210 210 SER SER A . n 
A 1 230 ARG 230 211 211 ARG ARG A . n 
A 1 231 ASN 231 212 212 ASN ASN A . n 
A 1 232 SER 232 213 213 SER SER A . n 
A 1 233 THR 233 214 214 THR THR A . n 
A 1 234 HIS 234 215 215 HIS HIS A . n 
A 1 235 GLU 235 216 216 GLU GLU A . n 
A 1 236 MET 236 217 217 MET MET A . n 
A 1 237 TYR 237 218 218 TYR TYR A . n 
A 1 238 TRP 238 219 219 TRP TRP A . n 
A 1 239 ILE 239 220 220 ILE ILE A . n 
A 1 240 SER 240 221 221 SER SER A . n 
A 1 241 ASN 241 222 222 ASN ASN A . n 
A 1 242 GLY 242 223 223 GLY GLY A . n 
A 1 243 THR 243 224 224 THR THR A . n 
A 1 244 GLY 244 225 225 GLY GLY A . n 
A 1 245 ASN 245 226 226 ASN ASN A . n 
A 1 246 ILE 246 227 227 ILE ILE A . n 
A 1 247 VAL 247 228 228 VAL VAL A . n 
A 1 248 SER 248 229 229 SER SER A . n 
A 1 249 SER 249 230 230 SER SER A . n 
A 1 250 VAL 250 231 231 VAL VAL A . n 
A 1 251 ASN 251 232 232 ASN ASN A . n 
A 1 252 MET 252 233 233 MET MET A . n 
A 1 253 VAL 253 234 234 VAL VAL A . n 
A 1 254 SER 254 235 235 SER SER A . n 
A 1 255 ARG 255 236 236 ARG ARG A . n 
A 1 256 LEU 256 237 237 LEU LEU A . n 
A 1 257 LEU 257 238 238 LEU LEU A . n 
A 1 258 LEU 258 239 239 LEU LEU A . n 
A 1 259 ASN 259 240 240 ASN ASN A . n 
A 1 260 ARG 260 241 241 ARG ARG A . n 
A 1 261 PHE 261 242 242 PHE PHE A . n 
A 1 262 THR 262 243 243 THR THR A . n 
A 1 263 MET 263 244 244 MET MET A . n 
A 1 264 THR 264 245 245 THR THR A . n 
A 1 265 HIS 265 246 246 HIS HIS A . n 
A 1 266 ARG 266 247 247 ARG ARG A . n 
A 1 267 ARG 267 248 248 ARG ARG A . n 
A 1 268 PRO 268 249 249 PRO PRO A . n 
A 1 269 THR 269 250 250 THR THR A . n 
A 1 270 ILE 270 251 251 ILE ILE A . n 
A 1 271 GLU 271 252 252 GLU GLU A . n 
A 1 272 LYS 272 253 253 LYS LYS A . n 
A 1 273 ASP 273 254 254 ASP ASP A . n 
A 1 274 VAL 274 255 255 VAL VAL A . n 
A 1 275 ASP 275 256 256 ASP ASP A . n 
A 1 276 LEU 276 257 257 LEU LEU A . n 
A 1 277 GLY 277 258 258 GLY GLY A . n 
A 1 278 ALA 278 259 259 ALA ALA A . n 
A 1 279 GLY 279 260 260 GLY GLY A . n 
A 1 280 THR 280 261 261 THR THR A . n 
A 1 281 ARG 281 262 262 ARG ARG A . n 
A 1 282 HIS 282 263 ?   ?   ?   A . n 
A 1 283 VAL 283 264 ?   ?   ?   A . n 
A 1 284 ASN 284 265 ?   ?   ?   A . n 
B 1 1   HIS 1   -18 ?   ?   ?   B . n 
B 1 2   HIS 2   -17 ?   ?   ?   B . n 
B 1 3   HIS 3   -16 ?   ?   ?   B . n 
B 1 4   HIS 4   -15 ?   ?   ?   B . n 
B 1 5   HIS 5   -14 ?   ?   ?   B . n 
B 1 6   HIS 6   -13 ?   ?   ?   B . n 
B 1 7   SER 7   -12 ?   ?   ?   B . n 
B 1 8   SER 8   -11 ?   ?   ?   B . n 
B 1 9   GLY 9   -10 ?   ?   ?   B . n 
B 1 10  LEU 10  -9  ?   ?   ?   B . n 
B 1 11  VAL 11  -8  ?   ?   ?   B . n 
B 1 12  PRO 12  -7  ?   ?   ?   B . n 
B 1 13  ARG 13  -6  ?   ?   ?   B . n 
B 1 14  GLY 14  -5  ?   ?   ?   B . n 
B 1 15  SER 15  -4  ?   ?   ?   B . n 
B 1 16  HIS 16  -3  ?   ?   ?   B . n 
B 1 17  MET 17  -2  ?   ?   ?   B . n 
B 1 18  ALA 18  -1  ?   ?   ?   B . n 
B 1 19  SER 19  0   ?   ?   ?   B . n 
B 1 20  GLY 20  1   ?   ?   ?   B . n 
B 1 21  THR 21  2   ?   ?   ?   B . n 
B 1 22  GLY 22  3   ?   ?   ?   B . n 
B 1 23  SER 23  4   ?   ?   ?   B . n 
B 1 24  GLN 24  5   ?   ?   ?   B . n 
B 1 25  GLY 25  6   ?   ?   ?   B . n 
B 1 26  GLU 26  7   7   GLU GLU B . n 
B 1 27  THR 27  8   8   THR THR B . n 
B 1 28  LEU 28  9   9   LEU LEU B . n 
B 1 29  GLY 29  10  10  GLY GLY B . n 
B 1 30  GLU 30  11  11  GLU GLU B . n 
B 1 31  LYS 31  12  12  LYS LYS B . n 
B 1 32  TRP 32  13  13  TRP TRP B . n 
B 1 33  LYS 33  14  14  LYS LYS B . n 
B 1 34  LYS 34  15  15  LYS LYS B . n 
B 1 35  LYS 35  16  16  LYS LYS B . n 
B 1 36  LEU 36  17  17  LEU LEU B . n 
B 1 37  ASN 37  18  18  ASN ASN B . n 
B 1 38  GLN 38  19  19  GLN GLN B . n 
B 1 39  LEU 39  20  20  LEU LEU B . n 
B 1 40  SER 40  21  21  SER SER B . n 
B 1 41  ARG 41  22  22  ARG ARG B . n 
B 1 42  LYS 42  23  23  LYS LYS B . n 
B 1 43  GLU 43  24  24  GLU GLU B . n 
B 1 44  PHE 44  25  25  PHE PHE B . n 
B 1 45  ASP 45  26  26  ASP ASP B . n 
B 1 46  LEU 46  27  27  LEU LEU B . n 
B 1 47  TYR 47  28  28  TYR TYR B . n 
B 1 48  LYS 48  29  29  LYS LYS B . n 
B 1 49  LYS 49  30  30  LYS LYS B . n 
B 1 50  SER 50  31  31  SER SER B . n 
B 1 51  GLY 51  32  32  GLY GLY B . n 
B 1 52  ILE 52  33  33  ILE ILE B . n 
B 1 53  THR 53  34  34  THR THR B . n 
B 1 54  GLU 54  35  35  GLU GLU B . n 
B 1 55  VAL 55  36  36  VAL VAL B . n 
B 1 56  ASP 56  37  37  ASP ASP B . n 
B 1 57  ARG 57  38  38  ARG ARG B . n 
B 1 58  THR 58  39  39  THR THR B . n 
B 1 59  GLU 59  40  40  GLU GLU B . n 
B 1 60  ALA 60  41  41  ALA ALA B . n 
B 1 61  LYS 61  42  42  LYS LYS B . n 
B 1 62  GLU 62  43  43  GLU GLU B . n 
B 1 63  GLY 63  44  44  GLY GLY B . n 
B 1 64  LEU 64  45  45  LEU LEU B . n 
B 1 65  LYS 65  46  46  LYS LYS B . n 
B 1 66  ARG 66  47  47  ARG ARG B . n 
B 1 67  GLY 67  48  48  GLY GLY B . n 
B 1 68  GLU 68  49  49  GLU GLU B . n 
B 1 69  THR 69  50  50  THR THR B . n 
B 1 70  THR 70  51  51  THR THR B . n 
B 1 71  HIS 71  52  52  HIS HIS B . n 
B 1 72  HIS 72  53  53  HIS HIS B . n 
B 1 73  ALA 73  54  54  ALA ALA B . n 
B 1 74  VAL 74  55  55  VAL VAL B . n 
B 1 75  SER 75  56  56  SER SER B . n 
B 1 76  ARG 76  57  57  ARG ARG B . n 
B 1 77  GLY 77  58  58  GLY GLY B . n 
B 1 78  SER 78  59  59  SER SER B . n 
B 1 79  ALA 79  60  60  ALA ALA B . n 
B 1 80  LYS 80  61  61  LYS LYS B . n 
B 1 81  LEU 81  62  62  LEU LEU B . n 
B 1 82  GLN 82  63  63  GLN GLN B . n 
B 1 83  TRP 83  64  64  TRP TRP B . n 
B 1 84  PHE 84  65  65  PHE PHE B . n 
B 1 85  VAL 85  66  66  VAL VAL B . n 
B 1 86  GLU 86  67  67  GLU GLU B . n 
B 1 87  ARG 87  68  68  ARG ARG B . n 
B 1 88  ASN 88  69  69  ASN ASN B . n 
B 1 89  MET 89  70  70  MET MET B . n 
B 1 90  VAL 90  71  71  VAL VAL B . n 
B 1 91  ILE 91  72  72  ILE ILE B . n 
B 1 92  PRO 92  73  73  PRO PRO B . n 
B 1 93  GLU 93  74  74  GLU GLU B . n 
B 1 94  GLY 94  75  75  GLY GLY B . n 
B 1 95  ARG 95  76  76  ARG ARG B . n 
B 1 96  VAL 96  77  77  VAL VAL B . n 
B 1 97  ILE 97  78  78  ILE ILE B . n 
B 1 98  ASP 98  79  79  ASP ASP B . n 
B 1 99  LEU 99  80  80  LEU LEU B . n 
B 1 100 GLY 100 81  81  GLY GLY B . n 
B 1 101 CYS 101 82  82  CYS CYS B . n 
B 1 102 GLY 102 83  83  GLY GLY B . n 
B 1 103 ARG 103 84  84  ARG ARG B . n 
B 1 104 GLY 104 85  85  GLY GLY B . n 
B 1 105 GLY 105 86  86  GLY GLY B . n 
B 1 106 TRP 106 87  87  TRP TRP B . n 
B 1 107 SER 107 88  88  SER SER B . n 
B 1 108 TYR 108 89  89  TYR TYR B . n 
B 1 109 TYR 109 90  90  TYR TYR B . n 
B 1 110 CYS 110 91  91  CYS CYS B . n 
B 1 111 ALA 111 92  92  ALA ALA B . n 
B 1 112 GLY 112 93  93  GLY GLY B . n 
B 1 113 LEU 113 94  94  LEU LEU B . n 
B 1 114 LYS 114 95  95  LYS LYS B . n 
B 1 115 LYS 115 96  96  LYS LYS B . n 
B 1 116 VAL 116 97  97  VAL VAL B . n 
B 1 117 THR 117 98  98  THR THR B . n 
B 1 118 GLU 118 99  99  GLU GLU B . n 
B 1 119 VAL 119 100 100 VAL VAL B . n 
B 1 120 ARG 120 101 101 ARG ARG B . n 
B 1 121 GLY 121 102 102 GLY GLY B . n 
B 1 122 TYR 122 103 103 TYR TYR B . n 
B 1 123 THR 123 104 104 THR THR B . n 
B 1 124 LYS 124 105 105 LYS LYS B . n 
B 1 125 GLY 125 106 106 GLY GLY B . n 
B 1 126 GLY 126 107 107 GLY GLY B . n 
B 1 127 PRO 127 108 108 PRO PRO B . n 
B 1 128 GLY 128 109 109 GLY GLY B . n 
B 1 129 HIS 129 110 110 HIS HIS B . n 
B 1 130 GLU 130 111 111 GLU GLU B . n 
B 1 131 GLU 131 112 112 GLU GLU B . n 
B 1 132 PRO 132 113 113 PRO PRO B . n 
B 1 133 VAL 133 114 114 VAL VAL B . n 
B 1 134 PRO 134 115 115 PRO PRO B . n 
B 1 135 MET 135 116 116 MET MET B . n 
B 1 136 SER 136 117 117 SER SER B . n 
B 1 137 THR 137 118 118 THR THR B . n 
B 1 138 TYR 138 119 119 TYR TYR B . n 
B 1 139 GLY 139 120 120 GLY GLY B . n 
B 1 140 TRP 140 121 121 TRP TRP B . n 
B 1 141 ASN 141 122 122 ASN ASN B . n 
B 1 142 ILE 142 123 123 ILE ILE B . n 
B 1 143 VAL 143 124 124 VAL VAL B . n 
B 1 144 LYS 144 125 125 LYS LYS B . n 
B 1 145 LEU 145 126 126 LEU LEU B . n 
B 1 146 MET 146 127 127 MET MET B . n 
B 1 147 SER 147 128 128 SER SER B . n 
B 1 148 GLY 148 129 129 GLY GLY B . n 
B 1 149 LYS 149 130 130 LYS LYS B . n 
B 1 150 ASP 150 131 131 ASP ASP B . n 
B 1 151 VAL 151 132 132 VAL VAL B . n 
B 1 152 PHE 152 133 133 PHE PHE B . n 
B 1 153 TYR 153 134 134 TYR TYR B . n 
B 1 154 LEU 154 135 135 LEU LEU B . n 
B 1 155 PRO 155 136 136 PRO PRO B . n 
B 1 156 PRO 156 137 137 PRO PRO B . n 
B 1 157 GLU 157 138 138 GLU GLU B . n 
B 1 158 LYS 158 139 139 LYS LYS B . n 
B 1 159 CYS 159 140 140 CYS CYS B . n 
B 1 160 ASP 160 141 141 ASP ASP B . n 
B 1 161 THR 161 142 142 THR THR B . n 
B 1 162 LEU 162 143 143 LEU LEU B . n 
B 1 163 LEU 163 144 144 LEU LEU B . n 
B 1 164 CYS 164 145 145 CYS CYS B . n 
B 1 165 ASP 165 146 146 ASP ASP B . n 
B 1 166 ILE 166 147 147 ILE ILE B . n 
B 1 167 GLY 167 148 148 GLY GLY B . n 
B 1 168 GLU 168 149 149 GLU GLU B . n 
B 1 169 SER 169 150 150 SER SER B . n 
B 1 170 SER 170 151 151 SER SER B . n 
B 1 171 PRO 171 152 152 PRO PRO B . n 
B 1 172 SER 172 153 153 SER SER B . n 
B 1 173 PRO 173 154 154 PRO PRO B . n 
B 1 174 THR 174 155 155 THR THR B . n 
B 1 175 VAL 175 156 156 VAL VAL B . n 
B 1 176 GLU 176 157 157 GLU GLU B . n 
B 1 177 GLU 177 158 158 GLU GLU B . n 
B 1 178 SER 178 159 159 SER SER B . n 
B 1 179 ARG 179 160 160 ARG ARG B . n 
B 1 180 THR 180 161 161 THR THR B . n 
B 1 181 ILE 181 162 162 ILE ILE B . n 
B 1 182 ARG 182 163 163 ARG ARG B . n 
B 1 183 VAL 183 164 164 VAL VAL B . n 
B 1 184 LEU 184 165 165 LEU LEU B . n 
B 1 185 LYS 185 166 166 LYS LYS B . n 
B 1 186 MET 186 167 167 MET MET B . n 
B 1 187 VAL 187 168 168 VAL VAL B . n 
B 1 188 GLU 188 169 169 GLU GLU B . n 
B 1 189 PRO 189 170 170 PRO PRO B . n 
B 1 190 TRP 190 171 171 TRP TRP B . n 
B 1 191 LEU 191 172 172 LEU LEU B . n 
B 1 192 LYS 192 173 173 LYS LYS B . n 
B 1 193 ASN 193 174 174 ASN ASN B . n 
B 1 194 ASN 194 175 175 ASN ASN B . n 
B 1 195 GLN 195 176 176 GLN GLN B . n 
B 1 196 PHE 196 177 177 PHE PHE B . n 
B 1 197 CYS 197 178 178 CYS CYS B . n 
B 1 198 ILE 198 179 179 ILE ILE B . n 
B 1 199 LYS 199 180 180 LYS LYS B . n 
B 1 200 VAL 200 181 181 VAL VAL B . n 
B 1 201 LEU 201 182 182 LEU LEU B . n 
B 1 202 ASN 202 183 183 ASN ASN B . n 
B 1 203 PRO 203 184 184 PRO PRO B . n 
B 1 204 TYR 204 185 185 TYR TYR B . n 
B 1 205 MET 205 186 186 MET MET B . n 
B 1 206 PRO 206 187 187 PRO PRO B . n 
B 1 207 THR 207 188 188 THR THR B . n 
B 1 208 VAL 208 189 189 VAL VAL B . n 
B 1 209 ILE 209 190 190 ILE ILE B . n 
B 1 210 GLU 210 191 191 GLU GLU B . n 
B 1 211 HIS 211 192 192 HIS HIS B . n 
B 1 212 LEU 212 193 193 LEU LEU B . n 
B 1 213 GLU 213 194 194 GLU GLU B . n 
B 1 214 ARG 214 195 195 ARG ARG B . n 
B 1 215 LEU 215 196 196 LEU LEU B . n 
B 1 216 GLN 216 197 197 GLN GLN B . n 
B 1 217 ARG 217 198 198 ARG ARG B . n 
B 1 218 LYS 218 199 199 LYS LYS B . n 
B 1 219 HIS 219 200 200 HIS HIS B . n 
B 1 220 GLY 220 201 201 GLY GLY B . n 
B 1 221 GLY 221 202 202 GLY GLY B . n 
B 1 222 MET 222 203 203 MET MET B . n 
B 1 223 LEU 223 204 204 LEU LEU B . n 
B 1 224 VAL 224 205 205 VAL VAL B . n 
B 1 225 ARG 225 206 206 ARG ARG B . n 
B 1 226 ASN 226 207 207 ASN ASN B . n 
B 1 227 PRO 227 208 208 PRO PRO B . n 
B 1 228 LEU 228 209 209 LEU LEU B . n 
B 1 229 SER 229 210 210 SER SER B . n 
B 1 230 ARG 230 211 211 ARG ARG B . n 
B 1 231 ASN 231 212 212 ASN ASN B . n 
B 1 232 SER 232 213 213 SER SER B . n 
B 1 233 THR 233 214 214 THR THR B . n 
B 1 234 HIS 234 215 215 HIS HIS B . n 
B 1 235 GLU 235 216 216 GLU GLU B . n 
B 1 236 MET 236 217 217 MET MET B . n 
B 1 237 TYR 237 218 218 TYR TYR B . n 
B 1 238 TRP 238 219 219 TRP TRP B . n 
B 1 239 ILE 239 220 220 ILE ILE B . n 
B 1 240 SER 240 221 221 SER SER B . n 
B 1 241 ASN 241 222 222 ASN ASN B . n 
B 1 242 GLY 242 223 223 GLY GLY B . n 
B 1 243 THR 243 224 224 THR THR B . n 
B 1 244 GLY 244 225 225 GLY GLY B . n 
B 1 245 ASN 245 226 226 ASN ASN B . n 
B 1 246 ILE 246 227 227 ILE ILE B . n 
B 1 247 VAL 247 228 228 VAL VAL B . n 
B 1 248 SER 248 229 229 SER SER B . n 
B 1 249 SER 249 230 230 SER SER B . n 
B 1 250 VAL 250 231 231 VAL VAL B . n 
B 1 251 ASN 251 232 232 ASN ASN B . n 
B 1 252 MET 252 233 233 MET MET B . n 
B 1 253 VAL 253 234 234 VAL VAL B . n 
B 1 254 SER 254 235 235 SER SER B . n 
B 1 255 ARG 255 236 236 ARG ARG B . n 
B 1 256 LEU 256 237 237 LEU LEU B . n 
B 1 257 LEU 257 238 238 LEU LEU B . n 
B 1 258 LEU 258 239 239 LEU LEU B . n 
B 1 259 ASN 259 240 240 ASN ASN B . n 
B 1 260 ARG 260 241 241 ARG ARG B . n 
B 1 261 PHE 261 242 242 PHE PHE B . n 
B 1 262 THR 262 243 243 THR THR B . n 
B 1 263 MET 263 244 244 MET MET B . n 
B 1 264 THR 264 245 245 THR THR B . n 
B 1 265 HIS 265 246 246 HIS HIS B . n 
B 1 266 ARG 266 247 247 ARG ARG B . n 
B 1 267 ARG 267 248 248 ARG ARG B . n 
B 1 268 PRO 268 249 249 PRO PRO B . n 
B 1 269 THR 269 250 250 THR THR B . n 
B 1 270 ILE 270 251 251 ILE ILE B . n 
B 1 271 GLU 271 252 252 GLU GLU B . n 
B 1 272 LYS 272 253 253 LYS LYS B . n 
B 1 273 ASP 273 254 254 ASP ASP B . n 
B 1 274 VAL 274 255 255 VAL VAL B . n 
B 1 275 ASP 275 256 256 ASP ASP B . n 
B 1 276 LEU 276 257 257 LEU LEU B . n 
B 1 277 GLY 277 258 258 GLY GLY B . n 
B 1 278 ALA 278 259 259 ALA ALA B . n 
B 1 279 GLY 279 260 260 GLY GLY B . n 
B 1 280 THR 280 261 261 THR THR B . n 
B 1 281 ARG 281 262 262 ARG ARG B . n 
B 1 282 HIS 282 263 ?   ?   ?   B . n 
B 1 283 VAL 283 264 ?   ?   ?   B . n 
B 1 284 ASN 284 265 ?   ?   ?   B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        QAP 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   QAP 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 SAH 1  301 301 SAH SAH A . 
D 3 QAP 1  302 302 QAP LIG A . 
E 3 QAP 1  303 303 QAP LIG A . 
F 2 SAH 1  301 301 SAH SAH B . 
G 4 HOH 1  401 42  HOH HOH A . 
G 4 HOH 2  402 33  HOH HOH A . 
G 4 HOH 3  403 73  HOH HOH A . 
G 4 HOH 4  404 137 HOH HOH A . 
G 4 HOH 5  405 94  HOH HOH A . 
G 4 HOH 6  406 106 HOH HOH A . 
G 4 HOH 7  407 47  HOH HOH A . 
G 4 HOH 8  408 59  HOH HOH A . 
G 4 HOH 9  409 16  HOH HOH A . 
G 4 HOH 10 410 34  HOH HOH A . 
G 4 HOH 11 411 19  HOH HOH A . 
G 4 HOH 12 412 15  HOH HOH A . 
G 4 HOH 13 413 110 HOH HOH A . 
G 4 HOH 14 414 51  HOH HOH A . 
G 4 HOH 15 415 22  HOH HOH A . 
G 4 HOH 16 416 45  HOH HOH A . 
G 4 HOH 17 417 102 HOH HOH A . 
G 4 HOH 18 418 72  HOH HOH A . 
G 4 HOH 19 419 11  HOH HOH A . 
G 4 HOH 20 420 124 HOH HOH A . 
G 4 HOH 21 421 7   HOH HOH A . 
G 4 HOH 22 422 69  HOH HOH A . 
G 4 HOH 23 423 63  HOH HOH A . 
G 4 HOH 24 424 111 HOH HOH A . 
G 4 HOH 25 425 105 HOH HOH A . 
G 4 HOH 26 426 12  HOH HOH A . 
G 4 HOH 27 427 119 HOH HOH A . 
G 4 HOH 28 428 24  HOH HOH A . 
G 4 HOH 29 429 127 HOH HOH A . 
G 4 HOH 30 430 115 HOH HOH A . 
G 4 HOH 31 431 36  HOH HOH A . 
G 4 HOH 32 432 46  HOH HOH A . 
G 4 HOH 33 433 136 HOH HOH A . 
G 4 HOH 34 434 13  HOH HOH A . 
G 4 HOH 35 435 113 HOH HOH A . 
G 4 HOH 36 436 85  HOH HOH A . 
G 4 HOH 37 437 56  HOH HOH A . 
G 4 HOH 38 438 50  HOH HOH A . 
G 4 HOH 39 439 25  HOH HOH A . 
G 4 HOH 40 440 21  HOH HOH A . 
G 4 HOH 41 441 17  HOH HOH A . 
G 4 HOH 42 442 75  HOH HOH A . 
G 4 HOH 43 443 20  HOH HOH A . 
G 4 HOH 44 444 14  HOH HOH A . 
G 4 HOH 45 445 88  HOH HOH A . 
G 4 HOH 46 446 31  HOH HOH A . 
G 4 HOH 47 447 8   HOH HOH A . 
G 4 HOH 48 448 10  HOH HOH A . 
G 4 HOH 49 449 92  HOH HOH A . 
G 4 HOH 50 450 91  HOH HOH A . 
G 4 HOH 51 451 132 HOH HOH A . 
G 4 HOH 52 452 112 HOH HOH A . 
G 4 HOH 53 453 29  HOH HOH A . 
G 4 HOH 54 454 128 HOH HOH A . 
G 4 HOH 55 455 52  HOH HOH A . 
G 4 HOH 56 456 4   HOH HOH A . 
G 4 HOH 57 457 5   HOH HOH A . 
G 4 HOH 58 458 130 HOH HOH A . 
G 4 HOH 59 459 139 HOH HOH A . 
G 4 HOH 60 460 68  HOH HOH A . 
G 4 HOH 61 461 140 HOH HOH A . 
G 4 HOH 62 462 70  HOH HOH A . 
G 4 HOH 63 463 40  HOH HOH A . 
G 4 HOH 64 464 114 HOH HOH A . 
G 4 HOH 65 465 103 HOH HOH A . 
G 4 HOH 66 466 133 HOH HOH A . 
G 4 HOH 67 467 79  HOH HOH A . 
G 4 HOH 68 468 81  HOH HOH A . 
H 4 HOH 1  401 131 HOH HOH B . 
H 4 HOH 2  402 66  HOH HOH B . 
H 4 HOH 3  403 104 HOH HOH B . 
H 4 HOH 4  404 30  HOH HOH B . 
H 4 HOH 5  405 37  HOH HOH B . 
H 4 HOH 6  406 38  HOH HOH B . 
H 4 HOH 7  407 74  HOH HOH B . 
H 4 HOH 8  408 117 HOH HOH B . 
H 4 HOH 9  409 84  HOH HOH B . 
H 4 HOH 10 410 39  HOH HOH B . 
H 4 HOH 11 411 96  HOH HOH B . 
H 4 HOH 12 412 76  HOH HOH B . 
H 4 HOH 13 413 107 HOH HOH B . 
H 4 HOH 14 414 35  HOH HOH B . 
H 4 HOH 15 415 49  HOH HOH B . 
H 4 HOH 16 416 108 HOH HOH B . 
H 4 HOH 17 417 116 HOH HOH B . 
H 4 HOH 18 418 58  HOH HOH B . 
H 4 HOH 19 419 86  HOH HOH B . 
H 4 HOH 20 420 64  HOH HOH B . 
H 4 HOH 21 421 98  HOH HOH B . 
H 4 HOH 22 422 27  HOH HOH B . 
H 4 HOH 23 423 77  HOH HOH B . 
H 4 HOH 24 424 89  HOH HOH B . 
H 4 HOH 25 425 54  HOH HOH B . 
H 4 HOH 26 426 26  HOH HOH B . 
H 4 HOH 27 427 55  HOH HOH B . 
H 4 HOH 28 428 134 HOH HOH B . 
H 4 HOH 29 429 71  HOH HOH B . 
H 4 HOH 30 430 65  HOH HOH B . 
H 4 HOH 31 431 123 HOH HOH B . 
H 4 HOH 32 432 126 HOH HOH B . 
H 4 HOH 33 433 28  HOH HOH B . 
H 4 HOH 34 434 48  HOH HOH B . 
H 4 HOH 35 435 138 HOH HOH B . 
H 4 HOH 36 436 129 HOH HOH B . 
H 4 HOH 37 437 90  HOH HOH B . 
H 4 HOH 38 438 67  HOH HOH B . 
H 4 HOH 39 439 121 HOH HOH B . 
H 4 HOH 40 440 60  HOH HOH B . 
H 4 HOH 41 441 125 HOH HOH B . 
H 4 HOH 42 442 41  HOH HOH B . 
H 4 HOH 43 443 135 HOH HOH B . 
H 4 HOH 44 444 23  HOH HOH B . 
H 4 HOH 45 445 61  HOH HOH B . 
H 4 HOH 46 446 122 HOH HOH B . 
H 4 HOH 47 447 32  HOH HOH B . 
H 4 HOH 48 448 87  HOH HOH B . 
H 4 HOH 49 449 120 HOH HOH B . 
H 4 HOH 50 450 78  HOH HOH B . 
H 4 HOH 51 451 118 HOH HOH B . 
H 4 HOH 52 452 99  HOH HOH B . 
H 4 HOH 53 453 53  HOH HOH B . 
H 4 HOH 54 454 18  HOH HOH B . 
H 4 HOH 55 455 80  HOH HOH B . 
H 4 HOH 56 456 82  HOH HOH B . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC      ? ? ? 5.8.0267 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? CrysalisPro ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? CrysalisPro ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? MOLREP      ? ? ? .        4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8KDZ 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     51.648 
_cell.length_a_esd                 ? 
_cell.length_b                     60.722 
_cell.length_b_esd                 ? 
_cell.length_c                     184.360 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8KDZ 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                18 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 2 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8KDZ 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.4122386 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          49.041695 
_exptl_crystal.description                  'Square Shaped' 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              8.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '25% PEG 8000 100 mM Tris 200 mM NaCl 20 mM Trisodium citrate' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'RIGAKU HyPix-6000HE' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-08-04 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.5418 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      'ROTATING ANODE' 
_diffrn_source.target                      ? 
_diffrn_source.type                        'RIGAKU MICROMAX-007 HF' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.5418 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   ? 
_diffrn_source.pdbx_synchrotron_site       ? 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8KDZ 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.60 
_reflns.d_resolution_low                               23.056 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     108535 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           98.6 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          7.3 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.188 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.6 
_reflns_shell.d_res_low                                     2.72 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             18527 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               0.421 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          99.3 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -2.711 
_refine.aniso_B[1][2]                            -0.000 
_refine.aniso_B[1][3]                            -0.000 
_refine.aniso_B[2][2]                            -2.122 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            4.833 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               28.803 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.894 
_refine.correlation_coeff_Fo_to_Fc_free          0.852 
_refine.details                                  'Hydrogens have not been used' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8KDZ 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.600 
_refine.ls_d_res_low                             23.056 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     108535 
_refine.ls_number_reflns_R_free                  924 
_refine.ls_number_reflns_R_work                  17543 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.328 
_refine.ls_percent_reflns_R_free                 5.004 
_refine.ls_R_factor_all                          0.233 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2727 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2310 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      4R8R 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       2.222 
_refine.pdbx_overall_ESU_R_Free                  0.358 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             14.568 
_refine.overall_SU_ML                            0.305 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.600 
_refine_hist.d_res_low                        23.056 
_refine_hist.number_atoms_solvent             124 
_refine_hist.number_atoms_total               4304 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        4086 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         94 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.007  0.012   4274  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.337  0.100   68107 ? r_ext_dist_refined_d           ? ? 
'X-RAY DIFFRACTION' ? 1.558  1.652   5764  ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 5.843  5.000   510   ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 32.516 20.545  220   ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 18.259 15.000  784   ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 18.661 15.000  38    ? r_dihedral_angle_4_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.097  0.200   532   ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.008  0.020   3202  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.214  0.200   1941  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.312  0.200   2882  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.149  0.200   150   ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.280  0.200   42    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.265  0.200   6     ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 1.501  2.742   2052  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 2.489  4.109   2558  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 2.136  3.030   2222  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 3.320  4.438   3206  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 7.097  101.264 70623 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 0.117  0.050   8368  ? r_ncsr_local_group_1           ? ? 
# 
loop_
_refine_ls_restr_ncs.pdbx_refine_id 
_refine_ls_restr_ncs.dom_id 
_refine_ls_restr_ncs.ncs_model_details 
_refine_ls_restr_ncs.rms_dev_B_iso 
_refine_ls_restr_ncs.rms_dev_position 
_refine_ls_restr_ncs.weight_B_iso 
_refine_ls_restr_ncs.weight_position 
_refine_ls_restr_ncs.pdbx_ordinal 
_refine_ls_restr_ncs.pdbx_type 
_refine_ls_restr_ncs.pdbx_asym_id 
_refine_ls_restr_ncs.pdbx_auth_asym_id 
_refine_ls_restr_ncs.pdbx_number 
_refine_ls_restr_ncs.pdbx_rms 
_refine_ls_restr_ncs.pdbx_weight 
_refine_ls_restr_ncs.pdbx_ens_id 
'X-RAY DIFFRACTION' 1 ? ? 0.11736 ? 0.05008 1 'Local ncs' ? A ? ? ? 1 
'X-RAY DIFFRACTION' 2 ? ? 0.11736 ? 0.05008 2 'Local ncs' ? B ? ? ? 1 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.600 2.668  . . 57 1276 98.8139  . . . . 0.306 . . . . . . . . . . . 0.309 
'X-RAY DIFFRACTION' 2.668 2.741  . . 75 1243 100.0000 . . . . 0.298 . . . . . . . . . . . 0.405 
'X-RAY DIFFRACTION' 2.741 2.820  . . 60 1198 99.9206  . . . . 0.294 . . . . . . . . . . . 0.331 
'X-RAY DIFFRACTION' 2.820 2.907  . . 54 1203 99.9205  . . . . 0.265 . . . . . . . . . . . 0.333 
'X-RAY DIFFRACTION' 2.907 3.002  . . 78 1110 100.0000 . . . . 0.245 . . . . . . . . . . . 0.277 
'X-RAY DIFFRACTION' 3.002 3.107  . . 56 1106 100.0000 . . . . 0.248 . . . . . . . . . . . 0.316 
'X-RAY DIFFRACTION' 3.107 3.225  . . 57 1101 99.9137  . . . . 0.260 . . . . . . . . . . . 0.307 
'X-RAY DIFFRACTION' 3.225 3.356  . . 39 1031 99.8134  . . . . 0.252 . . . . . . . . . . . 0.294 
'X-RAY DIFFRACTION' 3.356 3.506  . . 50 988  99.8077  . . . . 0.240 . . . . . . . . . . . 0.287 
'X-RAY DIFFRACTION' 3.506 3.677  . . 48 957  99.7024  . . . . 0.228 . . . . . . . . . . . 0.243 
'X-RAY DIFFRACTION' 3.677 3.875  . . 68 902  99.8970  . . . . 0.224 . . . . . . . . . . . 0.327 
'X-RAY DIFFRACTION' 3.875 4.110  . . 45 851  99.4451  . . . . 0.208 . . . . . . . . . . . 0.176 
'X-RAY DIFFRACTION' 4.110 4.394  . . 39 823  98.7400  . . . . 0.197 . . . . . . . . . . . 0.231 
'X-RAY DIFFRACTION' 4.394 4.746  . . 33 754  98.7453  . . . . 0.187 . . . . . . . . . . . 0.243 
'X-RAY DIFFRACTION' 4.746 5.198  . . 45 696  98.9319  . . . . 0.188 . . . . . . . . . . . 0.226 
'X-RAY DIFFRACTION' 5.198 5.812  . . 41 635  99.8523  . . . . 0.224 . . . . . . . . . . . 0.285 
'X-RAY DIFFRACTION' 5.812 6.709  . . 23 588  99.1883  . . . . 0.226 . . . . . . . . . . . 0.251 
'X-RAY DIFFRACTION' 6.709 8.215  . . 23 481  98.8235  . . . . 0.194 . . . . . . . . . . . 0.194 
'X-RAY DIFFRACTION' 8.0   10     . . 13 205  83.5249  . . . . 0.232 . . . . . . . . . . . 0.271 
'X-RAY DIFFRACTION' 8.215 11.606 . . 20 395  97.8774  . . . . 0.151 . . . . . . . . . . . 0.190 
# 
loop_
_struct_ncs_dom.id 
_struct_ncs_dom.pdbx_ens_id 
_struct_ncs_dom.details 
1 1 A 
2 1 B 
# 
loop_
_struct_ncs_dom_lim.pdbx_ens_id 
_struct_ncs_dom_lim.dom_id 
_struct_ncs_dom_lim.pdbx_component_id 
_struct_ncs_dom_lim.beg_label_asym_id 
_struct_ncs_dom_lim.beg_label_comp_id 
_struct_ncs_dom_lim.beg_label_seq_id 
_struct_ncs_dom_lim.beg_label_alt_id 
_struct_ncs_dom_lim.end_label_asym_id 
_struct_ncs_dom_lim.end_label_comp_id 
_struct_ncs_dom_lim.end_label_seq_id 
_struct_ncs_dom_lim.end_label_alt_id 
_struct_ncs_dom_lim.beg_auth_asym_id 
_struct_ncs_dom_lim.beg_auth_comp_id 
_struct_ncs_dom_lim.beg_auth_seq_id 
_struct_ncs_dom_lim.end_auth_asym_id 
_struct_ncs_dom_lim.end_auth_comp_id 
_struct_ncs_dom_lim.end_auth_seq_id 
_struct_ncs_dom_lim.pdbx_refine_code 
_struct_ncs_dom_lim.selection_details 
1 1 1 A GLU 26 . A ARG 281 . A GLU 7 A ARG 262 ? ? 
1 2 1 B GLU 26 . B ARG 281 . B GLU 7 B ARG 262 ? ? 
# 
_struct_ncs_ens.id        1 
_struct_ncs_ens.details   'Local NCS retraints between domains:       1       2' 
# 
_struct.entry_id                     8KDZ 
_struct.title                        
'DENGUE 3 NS5 METHYLTRANSFERASE BOUND TO S-Adenosyl-L-homocysteine and Caffeic acid phenethyl ester' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8KDZ 
_struct_keywords.text            'Inhibitor, Methyltransferase, Dengue 3, Antiviral, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 3 ? 
F N N 2 ? 
G N N 4 ? 
H N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    C1KBQ3_9FLAV 
_struct_ref.pdbx_db_accession          C1KBQ3 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;GTGSQGETLGEKWKKKLNQLSRKEFDLYKKSGITEVDRTEAKEGLKRGETTHHAVSRGSAKLQWFVERNMVIPEGRVIDL
GCGRGGWSYYCAGLKKVTEVRGYTKGGPGHEEPVPMSTYGWNIVKLMSGKDVFYLPPEKCDTLLCDIGESSPSPTVEESR
TIRVLKMVEPWLKNNQFCIKVLNPYMPTVIEHLERLQRKHGGMLVRNPLSRNSTHEMYWISNGTGNIVSSVNMVSRLLLN
RFTMTHRRPTIEKDVDLGAGTRHVN
;
_struct_ref.pdbx_align_begin           2491 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8KDZ A 20 ? 284 ? C1KBQ3 2491 ? 2755 ? 1 265 
2 1 8KDZ B 20 ? 284 ? C1KBQ3 2491 ? 2755 ? 1 265 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8KDZ HIS A 1  ? UNP C1KBQ3 ? ? 'expression tag' -18 1  
1 8KDZ HIS A 2  ? UNP C1KBQ3 ? ? 'expression tag' -17 2  
1 8KDZ HIS A 3  ? UNP C1KBQ3 ? ? 'expression tag' -16 3  
1 8KDZ HIS A 4  ? UNP C1KBQ3 ? ? 'expression tag' -15 4  
1 8KDZ HIS A 5  ? UNP C1KBQ3 ? ? 'expression tag' -14 5  
1 8KDZ HIS A 6  ? UNP C1KBQ3 ? ? 'expression tag' -13 6  
1 8KDZ SER A 7  ? UNP C1KBQ3 ? ? 'expression tag' -12 7  
1 8KDZ SER A 8  ? UNP C1KBQ3 ? ? 'expression tag' -11 8  
1 8KDZ GLY A 9  ? UNP C1KBQ3 ? ? 'expression tag' -10 9  
1 8KDZ LEU A 10 ? UNP C1KBQ3 ? ? 'expression tag' -9  10 
1 8KDZ VAL A 11 ? UNP C1KBQ3 ? ? 'expression tag' -8  11 
1 8KDZ PRO A 12 ? UNP C1KBQ3 ? ? 'expression tag' -7  12 
1 8KDZ ARG A 13 ? UNP C1KBQ3 ? ? 'expression tag' -6  13 
1 8KDZ GLY A 14 ? UNP C1KBQ3 ? ? 'expression tag' -5  14 
1 8KDZ SER A 15 ? UNP C1KBQ3 ? ? 'expression tag' -4  15 
1 8KDZ HIS A 16 ? UNP C1KBQ3 ? ? 'expression tag' -3  16 
1 8KDZ MET A 17 ? UNP C1KBQ3 ? ? 'expression tag' -2  17 
1 8KDZ ALA A 18 ? UNP C1KBQ3 ? ? 'expression tag' -1  18 
1 8KDZ SER A 19 ? UNP C1KBQ3 ? ? 'expression tag' 0   19 
2 8KDZ HIS B 1  ? UNP C1KBQ3 ? ? 'expression tag' -18 20 
2 8KDZ HIS B 2  ? UNP C1KBQ3 ? ? 'expression tag' -17 21 
2 8KDZ HIS B 3  ? UNP C1KBQ3 ? ? 'expression tag' -16 22 
2 8KDZ HIS B 4  ? UNP C1KBQ3 ? ? 'expression tag' -15 23 
2 8KDZ HIS B 5  ? UNP C1KBQ3 ? ? 'expression tag' -14 24 
2 8KDZ HIS B 6  ? UNP C1KBQ3 ? ? 'expression tag' -13 25 
2 8KDZ SER B 7  ? UNP C1KBQ3 ? ? 'expression tag' -12 26 
2 8KDZ SER B 8  ? UNP C1KBQ3 ? ? 'expression tag' -11 27 
2 8KDZ GLY B 9  ? UNP C1KBQ3 ? ? 'expression tag' -10 28 
2 8KDZ LEU B 10 ? UNP C1KBQ3 ? ? 'expression tag' -9  29 
2 8KDZ VAL B 11 ? UNP C1KBQ3 ? ? 'expression tag' -8  30 
2 8KDZ PRO B 12 ? UNP C1KBQ3 ? ? 'expression tag' -7  31 
2 8KDZ ARG B 13 ? UNP C1KBQ3 ? ? 'expression tag' -6  32 
2 8KDZ GLY B 14 ? UNP C1KBQ3 ? ? 'expression tag' -5  33 
2 8KDZ SER B 15 ? UNP C1KBQ3 ? ? 'expression tag' -4  34 
2 8KDZ HIS B 16 ? UNP C1KBQ3 ? ? 'expression tag' -3  35 
2 8KDZ MET B 17 ? UNP C1KBQ3 ? ? 'expression tag' -2  36 
2 8KDZ ALA B 18 ? UNP C1KBQ3 ? ? 'expression tag' -1  37 
2 8KDZ SER B 19 ? UNP C1KBQ3 ? ? 'expression tag' 0   38 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 27  ? GLN A 38  ? THR A 8   GLN A 19  1 ? 12 
HELX_P HELX_P2  AA2 SER A 40  ? LYS A 49  ? SER A 21  LYS A 30  1 ? 10 
HELX_P HELX_P3  AA3 ARG A 57  ? ARG A 66  ? ARG A 38  ARG A 47  1 ? 10 
HELX_P HELX_P4  AA4 ARG A 76  ? GLU A 86  ? ARG A 57  GLU A 67  1 ? 11 
HELX_P HELX_P5  AA5 GLY A 104 ? ALA A 111 ? GLY A 85  ALA A 92  1 ? 8  
HELX_P HELX_P6  AA6 GLY A 139 ? ASN A 141 ? GLY A 120 ASN A 122 5 ? 3  
HELX_P HELX_P7  AA7 ASP A 150 ? LEU A 154 ? ASP A 131 LEU A 135 5 ? 5  
HELX_P HELX_P8  AA8 SER A 172 ? GLU A 188 ? SER A 153 GLU A 169 1 ? 17 
HELX_P HELX_P9  AA9 PRO A 189 ? LEU A 191 ? PRO A 170 LEU A 172 5 ? 3  
HELX_P HELX_P10 AB1 MET A 205 ? GLY A 220 ? MET A 186 GLY A 201 1 ? 16 
HELX_P HELX_P11 AB2 ASN A 245 ? ARG A 260 ? ASN A 226 ARG A 241 1 ? 16 
HELX_P HELX_P12 AB3 THR B 27  ? GLN B 38  ? THR B 8   GLN B 19  1 ? 12 
HELX_P HELX_P13 AB4 SER B 40  ? LYS B 48  ? SER B 21  LYS B 29  1 ? 9  
HELX_P HELX_P14 AB5 ARG B 57  ? ARG B 66  ? ARG B 38  ARG B 47  1 ? 10 
HELX_P HELX_P15 AB6 ARG B 76  ? GLU B 86  ? ARG B 57  GLU B 67  1 ? 11 
HELX_P HELX_P16 AB7 GLY B 104 ? ALA B 111 ? GLY B 85  ALA B 92  1 ? 8  
HELX_P HELX_P17 AB8 GLY B 139 ? ASN B 141 ? GLY B 120 ASN B 122 5 ? 3  
HELX_P HELX_P18 AB9 ASP B 150 ? LEU B 154 ? ASP B 131 LEU B 135 5 ? 5  
HELX_P HELX_P19 AC1 SER B 172 ? GLU B 188 ? SER B 153 GLU B 169 1 ? 17 
HELX_P HELX_P20 AC2 PRO B 189 ? LEU B 191 ? PRO B 170 LEU B 172 5 ? 3  
HELX_P HELX_P21 AC3 MET B 205 ? GLY B 220 ? MET B 186 GLY B 201 1 ? 16 
HELX_P HELX_P22 AC4 ASN B 245 ? MET B 263 ? ASN B 226 MET B 244 1 ? 19 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 7 ? 
AA3 ? 2 ? 
AA4 ? 7 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA2 1 2 ? parallel      
AA2 2 3 ? parallel      
AA2 3 4 ? parallel      
AA2 4 5 ? parallel      
AA2 5 6 ? anti-parallel 
AA2 6 7 ? anti-parallel 
AA3 1 2 ? parallel      
AA4 1 2 ? parallel      
AA4 2 3 ? parallel      
AA4 3 4 ? parallel      
AA4 4 5 ? parallel      
AA4 5 6 ? anti-parallel 
AA4 6 7 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 THR A 53  ? ASP A 56  ? THR A 34  ASP A 37  
AA1 2 THR A 269 ? LYS A 272 ? THR A 250 LYS A 253 
AA2 1 VAL A 143 ? MET A 146 ? VAL A 124 MET A 127 
AA2 2 VAL A 116 ? TYR A 122 ? VAL A 97  TYR A 103 
AA2 3 GLY A 94  ? LEU A 99  ? GLY A 75  LEU A 80  
AA2 4 THR A 161 ? CYS A 164 ? THR A 142 CYS A 145 
AA2 5 GLN A 195 ? VAL A 200 ? GLN A 176 VAL A 181 
AA2 6 MET A 236 ? ILE A 239 ? MET A 217 ILE A 220 
AA2 7 MET A 222 ? VAL A 224 ? MET A 203 VAL A 205 
AA3 1 THR B 53  ? ASP B 56  ? THR B 34  ASP B 37  
AA3 2 THR B 269 ? LYS B 272 ? THR B 250 LYS B 253 
AA4 1 VAL B 143 ? MET B 146 ? VAL B 124 MET B 127 
AA4 2 VAL B 116 ? TYR B 122 ? VAL B 97  TYR B 103 
AA4 3 GLY B 94  ? LEU B 99  ? GLY B 75  LEU B 80  
AA4 4 THR B 161 ? CYS B 164 ? THR B 142 CYS B 145 
AA4 5 GLN B 195 ? VAL B 200 ? GLN B 176 VAL B 181 
AA4 6 MET B 236 ? ILE B 239 ? MET B 217 ILE B 220 
AA4 7 MET B 222 ? VAL B 224 ? MET B 203 VAL B 205 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLU A 54  ? N GLU A 35  O THR A 269 ? O THR A 250 
AA2 1 2 O MET A 146 ? O MET A 127 N GLY A 121 ? N GLY A 102 
AA2 2 3 O GLU A 118 ? O GLU A 99  N VAL A 96  ? N VAL A 77  
AA2 3 4 N ILE A 97  ? N ILE A 78  O LEU A 163 ? O LEU A 144 
AA2 4 5 N LEU A 162 ? N LEU A 143 O GLN A 195 ? O GLN A 176 
AA2 5 6 N VAL A 200 ? N VAL A 181 O MET A 236 ? O MET A 217 
AA2 6 7 O ILE A 239 ? O ILE A 220 N MET A 222 ? N MET A 203 
AA3 1 2 N GLU B 54  ? N GLU B 35  O THR B 269 ? O THR B 250 
AA4 1 2 O MET B 146 ? O MET B 127 N GLY B 121 ? N GLY B 102 
AA4 2 3 O GLU B 118 ? O GLU B 99  N VAL B 96  ? N VAL B 77  
AA4 3 4 N ILE B 97  ? N ILE B 78  O LEU B 163 ? O LEU B 144 
AA4 4 5 N LEU B 162 ? N LEU B 143 O GLN B 195 ? O GLN B 176 
AA4 5 6 N VAL B 200 ? N VAL B 181 O MET B 236 ? O MET B 217 
AA4 6 7 O TYR B 237 ? O TYR B 218 N VAL B 224 ? N VAL B 205 
# 
_pdbx_entry_details.entry_id                   8KDZ 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   NH2 
_pdbx_validate_close_contact.auth_asym_id_1   B 
_pdbx_validate_close_contact.auth_comp_id_1   ARG 
_pdbx_validate_close_contact.auth_seq_id_1    76 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   OE1 
_pdbx_validate_close_contact.auth_asym_id_2   B 
_pdbx_validate_close_contact.auth_comp_id_2   GLU 
_pdbx_validate_close_contact.auth_seq_id_2    138 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.01 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 NE A ARG 84  ? ? CZ A ARG 84  ? ? NH2 A ARG 84  ? ? 117.10 120.30 -3.20  0.50 N 
2 1 CG A ARG 163 ? ? CD A ARG 163 ? ? NE  A ARG 163 ? ? 126.34 111.80 14.54  2.10 N 
3 1 NE A ARG 241 ? ? CZ A ARG 241 ? ? NH2 A ARG 241 ? ? 124.02 120.30 3.72   0.50 N 
4 1 CB A ARG 262 ? ? CA A ARG 262 ? ? C   A ARG 262 ? ? 95.61  110.40 -14.79 2.00 N 
5 1 CB A ARG 262 ? ? CG A ARG 262 ? ? CD  A ARG 262 ? ? 94.90  111.60 -16.70 2.60 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 HIS A 52  ? ? 80.18   -45.51 
2 1 LYS A 173 ? ? -155.66 86.00  
3 1 HIS B 52  ? ? 79.33   -47.02 
4 1 LYS B 173 ? ? -154.97 85.04  
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      B 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       456 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   6.27 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A HIS -18 ? A HIS 1   
2  1 Y 1 A HIS -17 ? A HIS 2   
3  1 Y 1 A HIS -16 ? A HIS 3   
4  1 Y 1 A HIS -15 ? A HIS 4   
5  1 Y 1 A HIS -14 ? A HIS 5   
6  1 Y 1 A HIS -13 ? A HIS 6   
7  1 Y 1 A SER -12 ? A SER 7   
8  1 Y 1 A SER -11 ? A SER 8   
9  1 Y 1 A GLY -10 ? A GLY 9   
10 1 Y 1 A LEU -9  ? A LEU 10  
11 1 Y 1 A VAL -8  ? A VAL 11  
12 1 Y 1 A PRO -7  ? A PRO 12  
13 1 Y 1 A ARG -6  ? A ARG 13  
14 1 Y 1 A GLY -5  ? A GLY 14  
15 1 Y 1 A SER -4  ? A SER 15  
16 1 Y 1 A HIS -3  ? A HIS 16  
17 1 Y 1 A MET -2  ? A MET 17  
18 1 Y 1 A ALA -1  ? A ALA 18  
19 1 Y 1 A SER 0   ? A SER 19  
20 1 Y 1 A GLY 1   ? A GLY 20  
21 1 Y 1 A THR 2   ? A THR 21  
22 1 Y 1 A GLY 3   ? A GLY 22  
23 1 Y 1 A SER 4   ? A SER 23  
24 1 Y 1 A GLN 5   ? A GLN 24  
25 1 Y 1 A GLY 6   ? A GLY 25  
26 1 Y 1 A HIS 263 ? A HIS 282 
27 1 Y 1 A VAL 264 ? A VAL 283 
28 1 Y 1 A ASN 265 ? A ASN 284 
29 1 Y 1 B HIS -18 ? B HIS 1   
30 1 Y 1 B HIS -17 ? B HIS 2   
31 1 Y 1 B HIS -16 ? B HIS 3   
32 1 Y 1 B HIS -15 ? B HIS 4   
33 1 Y 1 B HIS -14 ? B HIS 5   
34 1 Y 1 B HIS -13 ? B HIS 6   
35 1 Y 1 B SER -12 ? B SER 7   
36 1 Y 1 B SER -11 ? B SER 8   
37 1 Y 1 B GLY -10 ? B GLY 9   
38 1 Y 1 B LEU -9  ? B LEU 10  
39 1 Y 1 B VAL -8  ? B VAL 11  
40 1 Y 1 B PRO -7  ? B PRO 12  
41 1 Y 1 B ARG -6  ? B ARG 13  
42 1 Y 1 B GLY -5  ? B GLY 14  
43 1 Y 1 B SER -4  ? B SER 15  
44 1 Y 1 B HIS -3  ? B HIS 16  
45 1 Y 1 B MET -2  ? B MET 17  
46 1 Y 1 B ALA -1  ? B ALA 18  
47 1 Y 1 B SER 0   ? B SER 19  
48 1 Y 1 B GLY 1   ? B GLY 20  
49 1 Y 1 B THR 2   ? B THR 21  
50 1 Y 1 B GLY 3   ? B GLY 22  
51 1 Y 1 B SER 4   ? B SER 23  
52 1 Y 1 B GLN 5   ? B GLN 24  
53 1 Y 1 B GLY 6   ? B GLY 25  
54 1 Y 1 B HIS 263 ? B HIS 282 
55 1 Y 1 B VAL 264 ? B VAL 283 
56 1 Y 1 B ASN 265 ? B ASN 284 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N N N 1   
ALA CA     C N S 2   
ALA C      C N N 3   
ALA O      O N N 4   
ALA CB     C N N 5   
ALA OXT    O N N 6   
ALA H      H N N 7   
ALA H2     H N N 8   
ALA HA     H N N 9   
ALA HB1    H N N 10  
ALA HB2    H N N 11  
ALA HB3    H N N 12  
ALA HXT    H N N 13  
ARG N      N N N 14  
ARG CA     C N S 15  
ARG C      C N N 16  
ARG O      O N N 17  
ARG CB     C N N 18  
ARG CG     C N N 19  
ARG CD     C N N 20  
ARG NE     N N N 21  
ARG CZ     C N N 22  
ARG NH1    N N N 23  
ARG NH2    N N N 24  
ARG OXT    O N N 25  
ARG H      H N N 26  
ARG H2     H N N 27  
ARG HA     H N N 28  
ARG HB2    H N N 29  
ARG HB3    H N N 30  
ARG HG2    H N N 31  
ARG HG3    H N N 32  
ARG HD2    H N N 33  
ARG HD3    H N N 34  
ARG HE     H N N 35  
ARG HH11   H N N 36  
ARG HH12   H N N 37  
ARG HH21   H N N 38  
ARG HH22   H N N 39  
ARG HXT    H N N 40  
ASN N      N N N 41  
ASN CA     C N S 42  
ASN C      C N N 43  
ASN O      O N N 44  
ASN CB     C N N 45  
ASN CG     C N N 46  
ASN OD1    O N N 47  
ASN ND2    N N N 48  
ASN OXT    O N N 49  
ASN H      H N N 50  
ASN H2     H N N 51  
ASN HA     H N N 52  
ASN HB2    H N N 53  
ASN HB3    H N N 54  
ASN HD21   H N N 55  
ASN HD22   H N N 56  
ASN HXT    H N N 57  
ASP N      N N N 58  
ASP CA     C N S 59  
ASP C      C N N 60  
ASP O      O N N 61  
ASP CB     C N N 62  
ASP CG     C N N 63  
ASP OD1    O N N 64  
ASP OD2    O N N 65  
ASP OXT    O N N 66  
ASP H      H N N 67  
ASP H2     H N N 68  
ASP HA     H N N 69  
ASP HB2    H N N 70  
ASP HB3    H N N 71  
ASP HD2    H N N 72  
ASP HXT    H N N 73  
CYS N      N N N 74  
CYS CA     C N R 75  
CYS C      C N N 76  
CYS O      O N N 77  
CYS CB     C N N 78  
CYS SG     S N N 79  
CYS OXT    O N N 80  
CYS H      H N N 81  
CYS H2     H N N 82  
CYS HA     H N N 83  
CYS HB2    H N N 84  
CYS HB3    H N N 85  
CYS HG     H N N 86  
CYS HXT    H N N 87  
GLN N      N N N 88  
GLN CA     C N S 89  
GLN C      C N N 90  
GLN O      O N N 91  
GLN CB     C N N 92  
GLN CG     C N N 93  
GLN CD     C N N 94  
GLN OE1    O N N 95  
GLN NE2    N N N 96  
GLN OXT    O N N 97  
GLN H      H N N 98  
GLN H2     H N N 99  
GLN HA     H N N 100 
GLN HB2    H N N 101 
GLN HB3    H N N 102 
GLN HG2    H N N 103 
GLN HG3    H N N 104 
GLN HE21   H N N 105 
GLN HE22   H N N 106 
GLN HXT    H N N 107 
GLU N      N N N 108 
GLU CA     C N S 109 
GLU C      C N N 110 
GLU O      O N N 111 
GLU CB     C N N 112 
GLU CG     C N N 113 
GLU CD     C N N 114 
GLU OE1    O N N 115 
GLU OE2    O N N 116 
GLU OXT    O N N 117 
GLU H      H N N 118 
GLU H2     H N N 119 
GLU HA     H N N 120 
GLU HB2    H N N 121 
GLU HB3    H N N 122 
GLU HG2    H N N 123 
GLU HG3    H N N 124 
GLU HE2    H N N 125 
GLU HXT    H N N 126 
GLY N      N N N 127 
GLY CA     C N N 128 
GLY C      C N N 129 
GLY O      O N N 130 
GLY OXT    O N N 131 
GLY H      H N N 132 
GLY H2     H N N 133 
GLY HA2    H N N 134 
GLY HA3    H N N 135 
GLY HXT    H N N 136 
HIS N      N N N 137 
HIS CA     C N S 138 
HIS C      C N N 139 
HIS O      O N N 140 
HIS CB     C N N 141 
HIS CG     C Y N 142 
HIS ND1    N Y N 143 
HIS CD2    C Y N 144 
HIS CE1    C Y N 145 
HIS NE2    N Y N 146 
HIS OXT    O N N 147 
HIS H      H N N 148 
HIS H2     H N N 149 
HIS HA     H N N 150 
HIS HB2    H N N 151 
HIS HB3    H N N 152 
HIS HD1    H N N 153 
HIS HD2    H N N 154 
HIS HE1    H N N 155 
HIS HE2    H N N 156 
HIS HXT    H N N 157 
HOH O      O N N 158 
HOH H1     H N N 159 
HOH H2     H N N 160 
ILE N      N N N 161 
ILE CA     C N S 162 
ILE C      C N N 163 
ILE O      O N N 164 
ILE CB     C N S 165 
ILE CG1    C N N 166 
ILE CG2    C N N 167 
ILE CD1    C N N 168 
ILE OXT    O N N 169 
ILE H      H N N 170 
ILE H2     H N N 171 
ILE HA     H N N 172 
ILE HB     H N N 173 
ILE HG12   H N N 174 
ILE HG13   H N N 175 
ILE HG21   H N N 176 
ILE HG22   H N N 177 
ILE HG23   H N N 178 
ILE HD11   H N N 179 
ILE HD12   H N N 180 
ILE HD13   H N N 181 
ILE HXT    H N N 182 
LEU N      N N N 183 
LEU CA     C N S 184 
LEU C      C N N 185 
LEU O      O N N 186 
LEU CB     C N N 187 
LEU CG     C N N 188 
LEU CD1    C N N 189 
LEU CD2    C N N 190 
LEU OXT    O N N 191 
LEU H      H N N 192 
LEU H2     H N N 193 
LEU HA     H N N 194 
LEU HB2    H N N 195 
LEU HB3    H N N 196 
LEU HG     H N N 197 
LEU HD11   H N N 198 
LEU HD12   H N N 199 
LEU HD13   H N N 200 
LEU HD21   H N N 201 
LEU HD22   H N N 202 
LEU HD23   H N N 203 
LEU HXT    H N N 204 
LYS N      N N N 205 
LYS CA     C N S 206 
LYS C      C N N 207 
LYS O      O N N 208 
LYS CB     C N N 209 
LYS CG     C N N 210 
LYS CD     C N N 211 
LYS CE     C N N 212 
LYS NZ     N N N 213 
LYS OXT    O N N 214 
LYS H      H N N 215 
LYS H2     H N N 216 
LYS HA     H N N 217 
LYS HB2    H N N 218 
LYS HB3    H N N 219 
LYS HG2    H N N 220 
LYS HG3    H N N 221 
LYS HD2    H N N 222 
LYS HD3    H N N 223 
LYS HE2    H N N 224 
LYS HE3    H N N 225 
LYS HZ1    H N N 226 
LYS HZ2    H N N 227 
LYS HZ3    H N N 228 
LYS HXT    H N N 229 
MET N      N N N 230 
MET CA     C N S 231 
MET C      C N N 232 
MET O      O N N 233 
MET CB     C N N 234 
MET CG     C N N 235 
MET SD     S N N 236 
MET CE     C N N 237 
MET OXT    O N N 238 
MET H      H N N 239 
MET H2     H N N 240 
MET HA     H N N 241 
MET HB2    H N N 242 
MET HB3    H N N 243 
MET HG2    H N N 244 
MET HG3    H N N 245 
MET HE1    H N N 246 
MET HE2    H N N 247 
MET HE3    H N N 248 
MET HXT    H N N 249 
PHE N      N N N 250 
PHE CA     C N S 251 
PHE C      C N N 252 
PHE O      O N N 253 
PHE CB     C N N 254 
PHE CG     C Y N 255 
PHE CD1    C Y N 256 
PHE CD2    C Y N 257 
PHE CE1    C Y N 258 
PHE CE2    C Y N 259 
PHE CZ     C Y N 260 
PHE OXT    O N N 261 
PHE H      H N N 262 
PHE H2     H N N 263 
PHE HA     H N N 264 
PHE HB2    H N N 265 
PHE HB3    H N N 266 
PHE HD1    H N N 267 
PHE HD2    H N N 268 
PHE HE1    H N N 269 
PHE HE2    H N N 270 
PHE HZ     H N N 271 
PHE HXT    H N N 272 
PRO N      N N N 273 
PRO CA     C N S 274 
PRO C      C N N 275 
PRO O      O N N 276 
PRO CB     C N N 277 
PRO CG     C N N 278 
PRO CD     C N N 279 
PRO OXT    O N N 280 
PRO H      H N N 281 
PRO HA     H N N 282 
PRO HB2    H N N 283 
PRO HB3    H N N 284 
PRO HG2    H N N 285 
PRO HG3    H N N 286 
PRO HD2    H N N 287 
PRO HD3    H N N 288 
PRO HXT    H N N 289 
QAP C1     C N N 290 
QAP O1     O N N 291 
QAP C2     C Y N 292 
QAP O2     O N N 293 
QAP C3     C N N 294 
QAP O3     O N N 295 
QAP C4     C Y N 296 
QAP O4     O N N 297 
QAP C5     C Y N 298 
QAP C6     C Y N 299 
QAP C7     C Y N 300 
QAP C8     C Y N 301 
QAP C9     C Y N 302 
QAP C10    C Y N 303 
QAP C11    C Y N 304 
QAP C12    C N N 305 
QAP C13    C Y N 306 
QAP C14    C N N 307 
QAP C15    C Y N 308 
QAP C16    C Y N 309 
QAP C17    C N N 310 
QAP H1     H N N 311 
QAP H1A    H N N 312 
QAP HO2    H N N 313 
QAP H3     H N N 314 
QAP H3A    H N N 315 
QAP HO3    H N N 316 
QAP H4     H N N 317 
QAP H5     H N N 318 
QAP H7     H N N 319 
QAP H8     H N N 320 
QAP H9     H N N 321 
QAP H10    H N N 322 
QAP H11    H N N 323 
QAP H12    H N N 324 
QAP H16    H N N 325 
QAP H17    H N N 326 
SAH N      N N N 327 
SAH CA     C N S 328 
SAH CB     C N N 329 
SAH CG     C N N 330 
SAH SD     S N N 331 
SAH C      C N N 332 
SAH O      O N N 333 
SAH OXT    O N N 334 
SAH "C5'"  C N N 335 
SAH "C4'"  C N S 336 
SAH "O4'"  O N N 337 
SAH "C3'"  C N S 338 
SAH "O3'"  O N N 339 
SAH "C2'"  C N R 340 
SAH "O2'"  O N N 341 
SAH "C1'"  C N R 342 
SAH N9     N Y N 343 
SAH C8     C Y N 344 
SAH N7     N Y N 345 
SAH C5     C Y N 346 
SAH C6     C Y N 347 
SAH N6     N N N 348 
SAH N1     N Y N 349 
SAH C2     C Y N 350 
SAH N3     N Y N 351 
SAH C4     C Y N 352 
SAH HN1    H N N 353 
SAH HN2    H N N 354 
SAH HA     H N N 355 
SAH HB1    H N N 356 
SAH HB2    H N N 357 
SAH HG1    H N N 358 
SAH HG2    H N N 359 
SAH HXT    H N N 360 
SAH "H5'1" H N N 361 
SAH "H5'2" H N N 362 
SAH "H4'"  H N N 363 
SAH "H3'"  H N N 364 
SAH "HO3'" H N N 365 
SAH "H2'"  H N N 366 
SAH "HO2'" H N N 367 
SAH "H1'"  H N N 368 
SAH H8     H N N 369 
SAH HN61   H N N 370 
SAH HN62   H N N 371 
SAH H2     H N N 372 
SER N      N N N 373 
SER CA     C N S 374 
SER C      C N N 375 
SER O      O N N 376 
SER CB     C N N 377 
SER OG     O N N 378 
SER OXT    O N N 379 
SER H      H N N 380 
SER H2     H N N 381 
SER HA     H N N 382 
SER HB2    H N N 383 
SER HB3    H N N 384 
SER HG     H N N 385 
SER HXT    H N N 386 
THR N      N N N 387 
THR CA     C N S 388 
THR C      C N N 389 
THR O      O N N 390 
THR CB     C N R 391 
THR OG1    O N N 392 
THR CG2    C N N 393 
THR OXT    O N N 394 
THR H      H N N 395 
THR H2     H N N 396 
THR HA     H N N 397 
THR HB     H N N 398 
THR HG1    H N N 399 
THR HG21   H N N 400 
THR HG22   H N N 401 
THR HG23   H N N 402 
THR HXT    H N N 403 
TRP N      N N N 404 
TRP CA     C N S 405 
TRP C      C N N 406 
TRP O      O N N 407 
TRP CB     C N N 408 
TRP CG     C Y N 409 
TRP CD1    C Y N 410 
TRP CD2    C Y N 411 
TRP NE1    N Y N 412 
TRP CE2    C Y N 413 
TRP CE3    C Y N 414 
TRP CZ2    C Y N 415 
TRP CZ3    C Y N 416 
TRP CH2    C Y N 417 
TRP OXT    O N N 418 
TRP H      H N N 419 
TRP H2     H N N 420 
TRP HA     H N N 421 
TRP HB2    H N N 422 
TRP HB3    H N N 423 
TRP HD1    H N N 424 
TRP HE1    H N N 425 
TRP HE3    H N N 426 
TRP HZ2    H N N 427 
TRP HZ3    H N N 428 
TRP HH2    H N N 429 
TRP HXT    H N N 430 
TYR N      N N N 431 
TYR CA     C N S 432 
TYR C      C N N 433 
TYR O      O N N 434 
TYR CB     C N N 435 
TYR CG     C Y N 436 
TYR CD1    C Y N 437 
TYR CD2    C Y N 438 
TYR CE1    C Y N 439 
TYR CE2    C Y N 440 
TYR CZ     C Y N 441 
TYR OH     O N N 442 
TYR OXT    O N N 443 
TYR H      H N N 444 
TYR H2     H N N 445 
TYR HA     H N N 446 
TYR HB2    H N N 447 
TYR HB3    H N N 448 
TYR HD1    H N N 449 
TYR HD2    H N N 450 
TYR HE1    H N N 451 
TYR HE2    H N N 452 
TYR HH     H N N 453 
TYR HXT    H N N 454 
VAL N      N N N 455 
VAL CA     C N S 456 
VAL C      C N N 457 
VAL O      O N N 458 
VAL CB     C N N 459 
VAL CG1    C N N 460 
VAL CG2    C N N 461 
VAL OXT    O N N 462 
VAL H      H N N 463 
VAL H2     H N N 464 
VAL HA     H N N 465 
VAL HB     H N N 466 
VAL HG11   H N N 467 
VAL HG12   H N N 468 
VAL HG13   H N N 469 
VAL HG21   H N N 470 
VAL HG22   H N N 471 
VAL HG23   H N N 472 
VAL HXT    H N N 473 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
CYS N     CA     sing N N 70  
CYS N     H      sing N N 71  
CYS N     H2     sing N N 72  
CYS CA    C      sing N N 73  
CYS CA    CB     sing N N 74  
CYS CA    HA     sing N N 75  
CYS C     O      doub N N 76  
CYS C     OXT    sing N N 77  
CYS CB    SG     sing N N 78  
CYS CB    HB2    sing N N 79  
CYS CB    HB3    sing N N 80  
CYS SG    HG     sing N N 81  
CYS OXT   HXT    sing N N 82  
GLN N     CA     sing N N 83  
GLN N     H      sing N N 84  
GLN N     H2     sing N N 85  
GLN CA    C      sing N N 86  
GLN CA    CB     sing N N 87  
GLN CA    HA     sing N N 88  
GLN C     O      doub N N 89  
GLN C     OXT    sing N N 90  
GLN CB    CG     sing N N 91  
GLN CB    HB2    sing N N 92  
GLN CB    HB3    sing N N 93  
GLN CG    CD     sing N N 94  
GLN CG    HG2    sing N N 95  
GLN CG    HG3    sing N N 96  
GLN CD    OE1    doub N N 97  
GLN CD    NE2    sing N N 98  
GLN NE2   HE21   sing N N 99  
GLN NE2   HE22   sing N N 100 
GLN OXT   HXT    sing N N 101 
GLU N     CA     sing N N 102 
GLU N     H      sing N N 103 
GLU N     H2     sing N N 104 
GLU CA    C      sing N N 105 
GLU CA    CB     sing N N 106 
GLU CA    HA     sing N N 107 
GLU C     O      doub N N 108 
GLU C     OXT    sing N N 109 
GLU CB    CG     sing N N 110 
GLU CB    HB2    sing N N 111 
GLU CB    HB3    sing N N 112 
GLU CG    CD     sing N N 113 
GLU CG    HG2    sing N N 114 
GLU CG    HG3    sing N N 115 
GLU CD    OE1    doub N N 116 
GLU CD    OE2    sing N N 117 
GLU OE2   HE2    sing N N 118 
GLU OXT   HXT    sing N N 119 
GLY N     CA     sing N N 120 
GLY N     H      sing N N 121 
GLY N     H2     sing N N 122 
GLY CA    C      sing N N 123 
GLY CA    HA2    sing N N 124 
GLY CA    HA3    sing N N 125 
GLY C     O      doub N N 126 
GLY C     OXT    sing N N 127 
GLY OXT   HXT    sing N N 128 
HIS N     CA     sing N N 129 
HIS N     H      sing N N 130 
HIS N     H2     sing N N 131 
HIS CA    C      sing N N 132 
HIS CA    CB     sing N N 133 
HIS CA    HA     sing N N 134 
HIS C     O      doub N N 135 
HIS C     OXT    sing N N 136 
HIS CB    CG     sing N N 137 
HIS CB    HB2    sing N N 138 
HIS CB    HB3    sing N N 139 
HIS CG    ND1    sing Y N 140 
HIS CG    CD2    doub Y N 141 
HIS ND1   CE1    doub Y N 142 
HIS ND1   HD1    sing N N 143 
HIS CD2   NE2    sing Y N 144 
HIS CD2   HD2    sing N N 145 
HIS CE1   NE2    sing Y N 146 
HIS CE1   HE1    sing N N 147 
HIS NE2   HE2    sing N N 148 
HIS OXT   HXT    sing N N 149 
HOH O     H1     sing N N 150 
HOH O     H2     sing N N 151 
ILE N     CA     sing N N 152 
ILE N     H      sing N N 153 
ILE N     H2     sing N N 154 
ILE CA    C      sing N N 155 
ILE CA    CB     sing N N 156 
ILE CA    HA     sing N N 157 
ILE C     O      doub N N 158 
ILE C     OXT    sing N N 159 
ILE CB    CG1    sing N N 160 
ILE CB    CG2    sing N N 161 
ILE CB    HB     sing N N 162 
ILE CG1   CD1    sing N N 163 
ILE CG1   HG12   sing N N 164 
ILE CG1   HG13   sing N N 165 
ILE CG2   HG21   sing N N 166 
ILE CG2   HG22   sing N N 167 
ILE CG2   HG23   sing N N 168 
ILE CD1   HD11   sing N N 169 
ILE CD1   HD12   sing N N 170 
ILE CD1   HD13   sing N N 171 
ILE OXT   HXT    sing N N 172 
LEU N     CA     sing N N 173 
LEU N     H      sing N N 174 
LEU N     H2     sing N N 175 
LEU CA    C      sing N N 176 
LEU CA    CB     sing N N 177 
LEU CA    HA     sing N N 178 
LEU C     O      doub N N 179 
LEU C     OXT    sing N N 180 
LEU CB    CG     sing N N 181 
LEU CB    HB2    sing N N 182 
LEU CB    HB3    sing N N 183 
LEU CG    CD1    sing N N 184 
LEU CG    CD2    sing N N 185 
LEU CG    HG     sing N N 186 
LEU CD1   HD11   sing N N 187 
LEU CD1   HD12   sing N N 188 
LEU CD1   HD13   sing N N 189 
LEU CD2   HD21   sing N N 190 
LEU CD2   HD22   sing N N 191 
LEU CD2   HD23   sing N N 192 
LEU OXT   HXT    sing N N 193 
LYS N     CA     sing N N 194 
LYS N     H      sing N N 195 
LYS N     H2     sing N N 196 
LYS CA    C      sing N N 197 
LYS CA    CB     sing N N 198 
LYS CA    HA     sing N N 199 
LYS C     O      doub N N 200 
LYS C     OXT    sing N N 201 
LYS CB    CG     sing N N 202 
LYS CB    HB2    sing N N 203 
LYS CB    HB3    sing N N 204 
LYS CG    CD     sing N N 205 
LYS CG    HG2    sing N N 206 
LYS CG    HG3    sing N N 207 
LYS CD    CE     sing N N 208 
LYS CD    HD2    sing N N 209 
LYS CD    HD3    sing N N 210 
LYS CE    NZ     sing N N 211 
LYS CE    HE2    sing N N 212 
LYS CE    HE3    sing N N 213 
LYS NZ    HZ1    sing N N 214 
LYS NZ    HZ2    sing N N 215 
LYS NZ    HZ3    sing N N 216 
LYS OXT   HXT    sing N N 217 
MET N     CA     sing N N 218 
MET N     H      sing N N 219 
MET N     H2     sing N N 220 
MET CA    C      sing N N 221 
MET CA    CB     sing N N 222 
MET CA    HA     sing N N 223 
MET C     O      doub N N 224 
MET C     OXT    sing N N 225 
MET CB    CG     sing N N 226 
MET CB    HB2    sing N N 227 
MET CB    HB3    sing N N 228 
MET CG    SD     sing N N 229 
MET CG    HG2    sing N N 230 
MET CG    HG3    sing N N 231 
MET SD    CE     sing N N 232 
MET CE    HE1    sing N N 233 
MET CE    HE2    sing N N 234 
MET CE    HE3    sing N N 235 
MET OXT   HXT    sing N N 236 
PHE N     CA     sing N N 237 
PHE N     H      sing N N 238 
PHE N     H2     sing N N 239 
PHE CA    C      sing N N 240 
PHE CA    CB     sing N N 241 
PHE CA    HA     sing N N 242 
PHE C     O      doub N N 243 
PHE C     OXT    sing N N 244 
PHE CB    CG     sing N N 245 
PHE CB    HB2    sing N N 246 
PHE CB    HB3    sing N N 247 
PHE CG    CD1    doub Y N 248 
PHE CG    CD2    sing Y N 249 
PHE CD1   CE1    sing Y N 250 
PHE CD1   HD1    sing N N 251 
PHE CD2   CE2    doub Y N 252 
PHE CD2   HD2    sing N N 253 
PHE CE1   CZ     doub Y N 254 
PHE CE1   HE1    sing N N 255 
PHE CE2   CZ     sing Y N 256 
PHE CE2   HE2    sing N N 257 
PHE CZ    HZ     sing N N 258 
PHE OXT   HXT    sing N N 259 
PRO N     CA     sing N N 260 
PRO N     CD     sing N N 261 
PRO N     H      sing N N 262 
PRO CA    C      sing N N 263 
PRO CA    CB     sing N N 264 
PRO CA    HA     sing N N 265 
PRO C     O      doub N N 266 
PRO C     OXT    sing N N 267 
PRO CB    CG     sing N N 268 
PRO CB    HB2    sing N N 269 
PRO CB    HB3    sing N N 270 
PRO CG    CD     sing N N 271 
PRO CG    HG2    sing N N 272 
PRO CG    HG3    sing N N 273 
PRO CD    HD2    sing N N 274 
PRO CD    HD3    sing N N 275 
PRO OXT   HXT    sing N N 276 
QAP C1    C2     sing N N 277 
QAP C1    C3     sing N N 278 
QAP O1    C3     sing N N 279 
QAP O1    C14    sing N N 280 
QAP C2    C4     doub Y N 281 
QAP C2    C5     sing Y N 282 
QAP O2    C13    sing N N 283 
QAP O3    C15    sing N N 284 
QAP C4    C7     sing Y N 285 
QAP O4    C14    doub N N 286 
QAP C5    C8     doub Y N 287 
QAP C6    C10    doub Y N 288 
QAP C6    C11    sing Y N 289 
QAP C6    C12    sing N N 290 
QAP C7    C9     doub Y N 291 
QAP C8    C9     sing Y N 292 
QAP C10   C13    sing Y N 293 
QAP C11   C16    doub Y N 294 
QAP C12   C17    doub N E 295 
QAP C13   C15    doub Y N 296 
QAP C14   C17    sing N N 297 
QAP C15   C16    sing Y N 298 
QAP C1    H1     sing N N 299 
QAP C1    H1A    sing N N 300 
QAP O2    HO2    sing N N 301 
QAP C3    H3     sing N N 302 
QAP C3    H3A    sing N N 303 
QAP O3    HO3    sing N N 304 
QAP C4    H4     sing N N 305 
QAP C5    H5     sing N N 306 
QAP C7    H7     sing N N 307 
QAP C8    H8     sing N N 308 
QAP C9    H9     sing N N 309 
QAP C10   H10    sing N N 310 
QAP C11   H11    sing N N 311 
QAP C12   H12    sing N N 312 
QAP C16   H16    sing N N 313 
QAP C17   H17    sing N N 314 
SAH N     CA     sing N N 315 
SAH N     HN1    sing N N 316 
SAH N     HN2    sing N N 317 
SAH CA    CB     sing N N 318 
SAH CA    C      sing N N 319 
SAH CA    HA     sing N N 320 
SAH CB    CG     sing N N 321 
SAH CB    HB1    sing N N 322 
SAH CB    HB2    sing N N 323 
SAH CG    SD     sing N N 324 
SAH CG    HG1    sing N N 325 
SAH CG    HG2    sing N N 326 
SAH SD    "C5'"  sing N N 327 
SAH C     O      doub N N 328 
SAH C     OXT    sing N N 329 
SAH OXT   HXT    sing N N 330 
SAH "C5'" "C4'"  sing N N 331 
SAH "C5'" "H5'1" sing N N 332 
SAH "C5'" "H5'2" sing N N 333 
SAH "C4'" "O4'"  sing N N 334 
SAH "C4'" "C3'"  sing N N 335 
SAH "C4'" "H4'"  sing N N 336 
SAH "O4'" "C1'"  sing N N 337 
SAH "C3'" "O3'"  sing N N 338 
SAH "C3'" "C2'"  sing N N 339 
SAH "C3'" "H3'"  sing N N 340 
SAH "O3'" "HO3'" sing N N 341 
SAH "C2'" "O2'"  sing N N 342 
SAH "C2'" "C1'"  sing N N 343 
SAH "C2'" "H2'"  sing N N 344 
SAH "O2'" "HO2'" sing N N 345 
SAH "C1'" N9     sing N N 346 
SAH "C1'" "H1'"  sing N N 347 
SAH N9    C8     sing Y N 348 
SAH N9    C4     sing Y N 349 
SAH C8    N7     doub Y N 350 
SAH C8    H8     sing N N 351 
SAH N7    C5     sing Y N 352 
SAH C5    C6     sing Y N 353 
SAH C5    C4     doub Y N 354 
SAH C6    N6     sing N N 355 
SAH C6    N1     doub Y N 356 
SAH N6    HN61   sing N N 357 
SAH N6    HN62   sing N N 358 
SAH N1    C2     sing Y N 359 
SAH C2    N3     doub Y N 360 
SAH C2    H2     sing N N 361 
SAH N3    C4     sing Y N 362 
SER N     CA     sing N N 363 
SER N     H      sing N N 364 
SER N     H2     sing N N 365 
SER CA    C      sing N N 366 
SER CA    CB     sing N N 367 
SER CA    HA     sing N N 368 
SER C     O      doub N N 369 
SER C     OXT    sing N N 370 
SER CB    OG     sing N N 371 
SER CB    HB2    sing N N 372 
SER CB    HB3    sing N N 373 
SER OG    HG     sing N N 374 
SER OXT   HXT    sing N N 375 
THR N     CA     sing N N 376 
THR N     H      sing N N 377 
THR N     H2     sing N N 378 
THR CA    C      sing N N 379 
THR CA    CB     sing N N 380 
THR CA    HA     sing N N 381 
THR C     O      doub N N 382 
THR C     OXT    sing N N 383 
THR CB    OG1    sing N N 384 
THR CB    CG2    sing N N 385 
THR CB    HB     sing N N 386 
THR OG1   HG1    sing N N 387 
THR CG2   HG21   sing N N 388 
THR CG2   HG22   sing N N 389 
THR CG2   HG23   sing N N 390 
THR OXT   HXT    sing N N 391 
TRP N     CA     sing N N 392 
TRP N     H      sing N N 393 
TRP N     H2     sing N N 394 
TRP CA    C      sing N N 395 
TRP CA    CB     sing N N 396 
TRP CA    HA     sing N N 397 
TRP C     O      doub N N 398 
TRP C     OXT    sing N N 399 
TRP CB    CG     sing N N 400 
TRP CB    HB2    sing N N 401 
TRP CB    HB3    sing N N 402 
TRP CG    CD1    doub Y N 403 
TRP CG    CD2    sing Y N 404 
TRP CD1   NE1    sing Y N 405 
TRP CD1   HD1    sing N N 406 
TRP CD2   CE2    doub Y N 407 
TRP CD2   CE3    sing Y N 408 
TRP NE1   CE2    sing Y N 409 
TRP NE1   HE1    sing N N 410 
TRP CE2   CZ2    sing Y N 411 
TRP CE3   CZ3    doub Y N 412 
TRP CE3   HE3    sing N N 413 
TRP CZ2   CH2    doub Y N 414 
TRP CZ2   HZ2    sing N N 415 
TRP CZ3   CH2    sing Y N 416 
TRP CZ3   HZ3    sing N N 417 
TRP CH2   HH2    sing N N 418 
TRP OXT   HXT    sing N N 419 
TYR N     CA     sing N N 420 
TYR N     H      sing N N 421 
TYR N     H2     sing N N 422 
TYR CA    C      sing N N 423 
TYR CA    CB     sing N N 424 
TYR CA    HA     sing N N 425 
TYR C     O      doub N N 426 
TYR C     OXT    sing N N 427 
TYR CB    CG     sing N N 428 
TYR CB    HB2    sing N N 429 
TYR CB    HB3    sing N N 430 
TYR CG    CD1    doub Y N 431 
TYR CG    CD2    sing Y N 432 
TYR CD1   CE1    sing Y N 433 
TYR CD1   HD1    sing N N 434 
TYR CD2   CE2    doub Y N 435 
TYR CD2   HD2    sing N N 436 
TYR CE1   CZ     doub Y N 437 
TYR CE1   HE1    sing N N 438 
TYR CE2   CZ     sing Y N 439 
TYR CE2   HE2    sing N N 440 
TYR CZ    OH     sing N N 441 
TYR OH    HH     sing N N 442 
TYR OXT   HXT    sing N N 443 
VAL N     CA     sing N N 444 
VAL N     H      sing N N 445 
VAL N     H2     sing N N 446 
VAL CA    C      sing N N 447 
VAL CA    CB     sing N N 448 
VAL CA    HA     sing N N 449 
VAL C     O      doub N N 450 
VAL C     OXT    sing N N 451 
VAL CB    CG1    sing N N 452 
VAL CB    CG2    sing N N 453 
VAL CB    HB     sing N N 454 
VAL CG1   HG11   sing N N 455 
VAL CG1   HG12   sing N N 456 
VAL CG1   HG13   sing N N 457 
VAL CG2   HG21   sing N N 458 
VAL CG2   HG22   sing N N 459 
VAL CG2   HG23   sing N N 460 
VAL OXT   HXT    sing N N 461 
# 
_pdbx_audit_support.funding_organization   'Indian Council of Medical Research' 
_pdbx_audit_support.country                India 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   4R8R 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8KDZ 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.019362 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.016468 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.005424 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C  6  6  2.310  20.844 1.020 10.208 1.589 0.569  0.865 51.651 0.216   
H  1  1  0.493  10.511 0.323 26.126 0.140 3.142  0.041 57.800 0.003   
MG 12 12 5.427  2.828  2.176 79.261 1.228 0.381  2.310 7.194  1.023   
N  7  7  12.222 0.006  3.135 9.893  2.014 28.997 1.167 0.583  -11.538 
O  8  8  3.049  13.277 2.287 5.701  1.546 0.324  0.867 32.909 0.251   
S  16 16 6.905  1.468  5.203 22.215 1.438 0.254  1.586 56.172 1.184   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
_atom_site.pdbx_tls_group_id 
ATOM   1    N N     . GLU A 1 26  ? -23.862 25.440 34.325 1.000 43.063  0 7   GLU A N     1 ? ? 
ATOM   2    C CA    . GLU A 1 26  ? -22.856 25.596 35.411 1.000 42.433  0 7   GLU A CA    1 ? ? 
ATOM   3    C C     . GLU A 1 26  ? -22.221 24.250 35.760 1.000 39.879  0 7   GLU A C     1 ? ? 
ATOM   4    O O     . GLU A 1 26  ? -22.900 23.230 35.927 1.000 39.163  0 7   GLU A O     1 ? ? 
ATOM   5    C CB    . GLU A 1 26  ? -23.476 26.297 36.619 1.000 44.108  0 7   GLU A CB    1 ? ? 
ATOM   6    C CG    . GLU A 1 26  ? -22.681 26.158 37.909 1.000 50.563  0 7   GLU A CG    1 ? ? 
ATOM   7    C CD    . GLU A 1 26  ? -23.029 27.154 39.008 1.000 54.354  0 7   GLU A CD    1 ? ? 
ATOM   8    O OE1   . GLU A 1 26  ? -24.193 27.154 39.483 1.000 54.683  0 7   GLU A OE1   1 ? ? 
ATOM   9    O OE2   . GLU A 1 26  ? -22.184 28.017 39.340 1.000 59.597  0 7   GLU A OE2   1 ? ? 
ATOM   10   N N     . THR A 1 27  ? -20.902 24.292 35.951 1.000 38.039  0 8   THR A N     1 ? ? 
ATOM   11   C CA    . THR A 1 27  ? -20.139 23.075 36.188 1.000 36.502  0 8   THR A CA    1 ? ? 
ATOM   12   C C     . THR A 1 27  ? -20.274 22.637 37.645 1.000 35.646  0 8   THR A C     1 ? ? 
ATOM   13   O O     . THR A 1 27  ? -20.634 23.420 38.527 1.000 33.661  0 8   THR A O     1 ? ? 
ATOM   14   C CB    . THR A 1 27  ? -18.677 23.246 35.735 1.000 34.131  0 8   THR A CB    1 ? ? 
ATOM   15   O OG1   . THR A 1 27  ? -17.987 24.213 36.534 1.000 29.719  0 8   THR A OG1   1 ? ? 
ATOM   16   C CG2   . THR A 1 27  ? -18.593 23.654 34.284 1.000 32.233  0 8   THR A CG2   1 ? ? 
ATOM   17   N N     . LEU A 1 28  ? -19.947 21.362 37.884 1.000 33.511  0 9   LEU A N     1 ? ? 
ATOM   18   C CA    . LEU A 1 28  ? -19.890 20.848 39.244 1.000 33.559  0 9   LEU A CA    1 ? ? 
ATOM   19   C C     . LEU A 1 28  ? -18.805 21.571 40.032 1.000 35.176  0 9   LEU A C     1 ? ? 
ATOM   20   O O     . LEU A 1 28  ? -18.998 21.939 41.186 1.000 36.181  0 9   LEU A O     1 ? ? 
ATOM   21   C CB    . LEU A 1 28  ? -19.609 19.350 39.199 1.000 31.744  0 9   LEU A CB    1 ? ? 
ATOM   22   C CG    . LEU A 1 28  ? -20.852 18.474 39.250 1.000 31.625  0 9   LEU A CG    1 ? ? 
ATOM   23   C CD1   . LEU A 1 28  ? -20.506 17.072 38.833 1.000 32.117  0 9   LEU A CD1   1 ? ? 
ATOM   24   C CD2   . LEU A 1 28  ? -21.466 18.463 40.623 1.000 30.431  0 9   LEU A CD2   1 ? ? 
ATOM   25   N N     . GLY A 1 29  ? -17.681 21.842 39.368 1.000 34.152  0 10  GLY A N     1 ? ? 
ATOM   26   C CA    . GLY A 1 29  ? -16.597 22.558 40.010 1.000 31.996  0 10  GLY A CA    1 ? ? 
ATOM   27   C C     . GLY A 1 29  ? -17.022 23.957 40.433 1.000 30.992  0 10  GLY A C     1 ? ? 
ATOM   28   O O     . GLY A 1 29  ? -16.490 24.476 41.404 1.000 32.793  0 10  GLY A O     1 ? ? 
ATOM   29   N N     . GLU A 1 30  ? -17.918 24.586 39.671 1.000 29.435  0 11  GLU A N     1 ? ? 
ATOM   30   C CA    . GLU A 1 30  ? -18.302 25.948 39.987 1.000 29.272  0 11  GLU A CA    1 ? ? 
ATOM   31   C C     . GLU A 1 30  ? -19.148 25.961 41.251 1.000 27.403  0 11  GLU A C     1 ? ? 
ATOM   32   O O     . GLU A 1 30  ? -19.023 26.862 42.068 1.000 27.257  0 11  GLU A O     1 ? ? 
ATOM   33   C CB    . GLU A 1 30  ? -19.023 26.601 38.813 1.000 30.353  0 11  GLU A CB    1 ? ? 
ATOM   34   C CG    . GLU A 1 30  ? -18.094 27.281 37.815 1.000 31.955  0 11  GLU A CG    1 ? ? 
ATOM   35   C CD    . GLU A 1 30  ? -18.776 27.607 36.497 1.000 31.959  0 11  GLU A CD    1 ? ? 
ATOM   36   O OE1   . GLU A 1 30  ? -19.131 26.644 35.767 1.000 32.625  0 11  GLU A OE1   1 ? ? 
ATOM   37   O OE2   . GLU A 1 30  ? -18.974 28.809 36.211 1.000 33.353  0 11  GLU A OE2   1 ? ? 
ATOM   38   N N     . LYS A 1 31  ? -20.011 24.955 41.400 1.000 25.692  0 12  LYS A N     1 ? ? 
ATOM   39   C CA    . LYS A 1 31  ? -20.808 24.799 42.606 1.000 25.173  0 12  LYS A CA    1 ? ? 
ATOM   40   C C     . LYS A 1 31  ? -19.896 24.581 43.819 1.000 23.594  0 12  LYS A C     1 ? ? 
ATOM   41   O O     . LYS A 1 31  ? -20.067 25.206 44.871 1.000 22.922  0 12  LYS A O     1 ? ? 
ATOM   42   C CB    . LYS A 1 31  ? -21.799 23.645 42.408 1.000 25.783  0 12  LYS A CB    1 ? ? 
ATOM   43   C CG    . LYS A 1 31  ? -22.776 23.816 41.256 1.000 26.884  0 12  LYS A CG    1 ? ? 
ATOM   44   C CD    . LYS A 1 31  ? -23.194 22.528 40.590 1.000 27.579  0 12  LYS A CD    1 ? ? 
ATOM   45   C CE    . LYS A 1 31  ? -24.039 22.634 39.337 1.000 27.723  0 12  LYS A CE    1 ? ? 
ATOM   46   N NZ    . LYS A 1 31  ? -25.340 23.287 39.591 1.000 27.751  0 12  LYS A NZ    1 ? ? 
ATOM   47   N N     . TRP A 1 32  ? -18.893 23.719 43.634 1.000 23.671  0 13  TRP A N     1 ? ? 
ATOM   48   C CA    . TRP A 1 32  ? -17.892 23.480 44.661 1.000 25.061  0 13  TRP A CA    1 ? ? 
ATOM   49   C C     . TRP A 1 32  ? -17.249 24.795 45.117 1.000 25.101  0 13  TRP A C     1 ? ? 
ATOM   50   O O     . TRP A 1 32  ? -17.126 25.073 46.307 1.000 24.921  0 13  TRP A O     1 ? ? 
ATOM   51   C CB    . TRP A 1 32  ? -16.844 22.462 44.174 1.000 23.702  0 13  TRP A CB    1 ? ? 
ATOM   52   C CG    . TRP A 1 32  ? -15.606 22.471 45.011 1.000 22.674  0 13  TRP A CG    1 ? ? 
ATOM   53   C CD1   . TRP A 1 32  ? -15.422 21.863 46.219 1.000 22.485  0 13  TRP A CD1   1 ? ? 
ATOM   54   C CD2   . TRP A 1 32  ? -14.403 23.200 44.741 1.000 22.130  0 13  TRP A CD2   1 ? ? 
ATOM   55   N NE1   . TRP A 1 32  ? -14.180 22.141 46.708 1.000 23.218  0 13  TRP A NE1   1 ? ? 
ATOM   56   C CE2   . TRP A 1 32  ? -13.532 22.971 45.825 1.000 22.897  0 13  TRP A CE2   1 ? ? 
ATOM   57   C CE3   . TRP A 1 32  ? -13.975 24.014 43.690 1.000 23.158  0 13  TRP A CE3   1 ? ? 
ATOM   58   C CZ2   . TRP A 1 32  ? -12.240 23.506 45.873 1.000 23.090  0 13  TRP A CZ2   1 ? ? 
ATOM   59   C CZ3   . TRP A 1 32  ? -12.708 24.558 43.747 1.000 23.560  0 13  TRP A CZ3   1 ? ? 
ATOM   60   C CH2   . TRP A 1 32  ? -11.851 24.317 44.826 1.000 23.759  0 13  TRP A CH2   1 ? ? 
ATOM   61   N N     . LYS A 1 33  ? -16.821 25.608 44.155 1.000 26.360  0 14  LYS A N     1 ? ? 
ATOM   62   C CA    . LYS A 1 33  ? -16.154 26.859 44.464 1.000 29.198  0 14  LYS A CA    1 ? ? 
ATOM   63   C C     . LYS A 1 33  ? -17.051 27.771 45.306 1.000 30.777  0 14  LYS A C     1 ? ? 
ATOM   64   O O     . LYS A 1 33  ? -16.602 28.321 46.314 1.000 30.744  0 14  LYS A O     1 ? ? 
ATOM   65   C CB    . LYS A 1 33  ? -15.756 27.532 43.153 1.000 30.168  0 14  LYS A CB    1 ? ? 
ATOM   66   C CG    . LYS A 1 33  ? -14.895 28.768 43.303 1.000 31.359  0 14  LYS A CG    1 ? ? 
ATOM   67   C CD    . LYS A 1 33  ? -13.606 28.472 44.045 1.000 32.828  0 14  LYS A CD    1 ? ? 
ATOM   68   C CE    . LYS A 1 33  ? -12.437 29.266 43.520 1.000 32.727  0 14  LYS A CE    1 ? ? 
ATOM   69   N NZ    . LYS A 1 33  ? -11.203 28.931 44.253 1.000 33.022  0 14  LYS A NZ    1 ? ? 
ATOM   70   N N     . LYS A 1 34  ? -18.315 27.914 44.896 1.000 31.554  0 15  LYS A N     1 ? ? 
ATOM   71   C CA    . LYS A 1 34  ? -19.227 28.799 45.596 1.000 33.782  0 15  LYS A CA    1 ? ? 
ATOM   72   C C     . LYS A 1 34  ? -19.425 28.340 47.038 1.000 33.956  0 15  LYS A C     1 ? ? 
ATOM   73   O O     . LYS A 1 34  ? -19.469 29.162 47.951 1.000 34.420  0 15  LYS A O     1 ? ? 
ATOM   74   C CB    . LYS A 1 34  ? -20.592 28.785 44.919 1.000 38.929  0 15  LYS A CB    1 ? ? 
ATOM   75   C CG    . LYS A 1 34  ? -20.696 29.569 43.626 1.000 46.524  0 15  LYS A CG    1 ? ? 
ATOM   76   C CD    . LYS A 1 34  ? -21.964 29.204 42.867 1.000 50.125  0 15  LYS A CD    1 ? ? 
ATOM   77   C CE    . LYS A 1 34  ? -22.367 30.226 41.825 1.000 54.398  0 15  LYS A CE    1 ? ? 
ATOM   78   N NZ    . LYS A 1 34  ? -22.906 31.468 42.429 1.000 56.672  0 15  LYS A NZ    1 ? ? 
ATOM   79   N N     . LYS A 1 35  ? -19.554 27.018 47.215 1.000 30.986  0 16  LYS A N     1 ? ? 
ATOM   80   C CA    . LYS A 1 35  ? -19.681 26.430 48.535 1.000 29.877  0 16  LYS A CA    1 ? ? 
ATOM   81   C C     . LYS A 1 35  ? -18.411 26.693 49.335 1.000 29.285  0 16  LYS A C     1 ? ? 
ATOM   82   O O     . LYS A 1 35  ? -18.487 26.998 50.525 1.000 29.992  0 16  LYS A O     1 ? ? 
ATOM   83   C CB    . LYS A 1 35  ? -20.033 24.949 48.460 1.000 28.682  0 16  LYS A CB    1 ? ? 
ATOM   84   C CG    . LYS A 1 35  ? -21.476 24.681 48.080 1.000 29.133  0 16  LYS A CG    1 ? ? 
ATOM   85   C CD    . LYS A 1 35  ? -21.901 23.268 48.427 1.000 29.737  0 16  LYS A CD    1 ? ? 
ATOM   86   C CE    . LYS A 1 35  ? -23.394 23.033 48.319 1.000 28.834  0 16  LYS A CE    1 ? ? 
ATOM   87   N NZ    . LYS A 1 35  ? -23.856 22.023 49.301 1.000 28.451  0 16  LYS A NZ    1 ? ? 
ATOM   88   N N     . LEU A 1 36  ? -17.251 26.551 48.691 1.000 27.759  0 17  LEU A N     1 ? ? 
ATOM   89   C CA    . LEU A 1 36  ? -15.996 26.762 49.399 1.000 26.667  0 17  LEU A CA    1 ? ? 
ATOM   90   C C     . LEU A 1 36  ? -15.873 28.207 49.872 1.000 26.161  0 17  LEU A C     1 ? ? 
ATOM   91   O O     . LEU A 1 36  ? -15.462 28.457 51.003 1.000 24.733  0 17  LEU A O     1 ? ? 
ATOM   92   C CB    . LEU A 1 36  ? -14.833 26.387 48.482 1.000 26.254  0 17  LEU A CB    1 ? ? 
ATOM   93   C CG    . LEU A 1 36  ? -13.442 26.509 49.102 1.000 26.338  0 17  LEU A CG    1 ? ? 
ATOM   94   C CD1   . LEU A 1 36  ? -13.101 25.265 49.902 1.000 26.111  0 17  LEU A CD1   1 ? ? 
ATOM   95   C CD2   . LEU A 1 36  ? -12.388 26.736 48.028 1.000 23.772  0 17  LEU A CD2   1 ? ? 
ATOM   96   N N     . ASN A 1 37  ? -16.294 29.145 49.021 1.000 27.465  0 18  ASN A N     1 ? ? 
ATOM   97   C CA    . ASN A 1 37  ? -16.184 30.566 49.329 1.000 27.169  0 18  ASN A CA    1 ? ? 
ATOM   98   C C     . ASN A 1 37  ? -17.095 30.972 50.485 1.000 28.374  0 18  ASN A C     1 ? ? 
ATOM   99   O O     . ASN A 1 37  ? -16.812 32.001 51.088 1.000 27.314  0 18  ASN A O     1 ? ? 
ATOM   100  C CB    . ASN A 1 37  ? -16.503 31.448 48.117 1.000 26.580  0 18  ASN A CB    1 ? ? 
ATOM   101  C CG    . ASN A 1 37  ? -15.394 31.457 47.090 1.000 25.481  0 18  ASN A CG    1 ? ? 
ATOM   102  O OD1   . ASN A 1 37  ? -14.222 31.383 47.448 1.000 24.434  0 18  ASN A OD1   1 ? ? 
ATOM   103  N ND2   . ASN A 1 37  ? -15.743 31.576 45.818 1.000 24.893  0 18  ASN A ND2   1 ? ? 
ATOM   104  N N     . GLN A 1 38  ? -18.186 30.220 50.764 1.000 29.722  0 19  GLN A N     1 ? ? 
ATOM   105  C CA    . GLN A 1 38  ? -19.086 30.605 51.843 1.000 30.062  0 19  GLN A CA    1 ? ? 
ATOM   106  C C     . GLN A 1 38  ? -18.626 30.052 53.192 1.000 30.163  0 19  GLN A C     1 ? ? 
ATOM   107  O O     . GLN A 1 38  ? -19.234 30.382 54.203 1.000 30.158  0 19  GLN A O     1 ? ? 
ATOM   108  C CB    . GLN A 1 38  ? -20.531 30.095 51.723 1.000 31.931  0 19  GLN A CB    1 ? ? 
ATOM   109  C CG    . GLN A 1 38  ? -21.222 30.189 50.376 1.000 34.207  0 19  GLN A CG    1 ? ? 
ATOM   110  C CD    . GLN A 1 38  ? -22.089 28.965 50.168 1.000 34.858  0 19  GLN A CD    1 ? ? 
ATOM   111  O OE1   . GLN A 1 38  ? -22.206 28.098 51.037 1.000 33.827  0 19  GLN A OE1   1 ? ? 
ATOM   112  N NE2   . GLN A 1 38  ? -22.721 28.890 49.007 1.000 35.315  0 19  GLN A NE2   1 ? ? 
ATOM   113  N N     . LEU A 1 39  ? -17.573 29.228 53.223 1.000 30.530  0 20  LEU A N     1 ? ? 
ATOM   114  C CA    . LEU A 1 39  ? -17.158 28.646 54.490 1.000 30.536  0 20  LEU A CA    1 ? ? 
ATOM   115  C C     . LEU A 1 39  ? -16.527 29.698 55.398 1.000 29.862  0 20  LEU A C     1 ? ? 
ATOM   116  O O     . LEU A 1 39  ? -15.841 30.613 54.953 1.000 29.884  0 20  LEU A O     1 ? ? 
ATOM   117  C CB    . LEU A 1 39  ? -16.161 27.511 54.246 1.000 29.893  0 20  LEU A CB    1 ? ? 
ATOM   118  C CG    . LEU A 1 39  ? -16.664 26.233 53.569 1.000 29.523  0 20  LEU A CG    1 ? ? 
ATOM   119  C CD1   . LEU A 1 39  ? -15.556 25.190 53.742 1.000 29.497  0 20  LEU A CD1   1 ? ? 
ATOM   120  C CD2   . LEU A 1 39  ? -17.946 25.704 54.226 1.000 28.916  0 20  LEU A CD2   1 ? ? 
ATOM   121  N N     . SER A 1 40  ? -16.748 29.512 56.695 1.000 28.418  0 21  SER A N     1 ? ? 
ATOM   122  C CA    . SER A 1 40  ? -16.050 30.260 57.717 1.000 27.386  0 21  SER A CA    1 ? ? 
ATOM   123  C C     . SER A 1 40  ? -14.607 29.789 57.708 1.000 27.350  0 21  SER A C     1 ? ? 
ATOM   124  O O     . SER A 1 40  ? -14.337 28.726 57.165 1.000 27.953  0 21  SER A O     1 ? ? 
ATOM   125  C CB    . SER A 1 40  ? -16.689 30.023 59.047 1.000 27.746  0 21  SER A CB    1 ? ? 
ATOM   126  O OG    . SER A 1 40  ? -15.959 29.081 59.784 1.000 28.881  0 21  SER A OG    1 ? ? 
ATOM   127  N N     . ARG A 1 41  ? -13.703 30.585 58.276 1.000 28.407  0 22  ARG A N     1 ? ? 
ATOM   128  C CA    . ARG A 1 41  ? -12.316 30.158 58.338 1.000 30.125  0 22  ARG A CA    1 ? ? 
ATOM   129  C C     . ARG A 1 41  ? -12.182 28.867 59.144 1.000 31.714  0 22  ARG A C     1 ? ? 
ATOM   130  O O     . ARG A 1 41  ? -11.330 28.049 58.819 1.000 32.032  0 22  ARG A O     1 ? ? 
ATOM   131  C CB    . ARG A 1 41  ? -11.401 31.266 58.864 1.000 31.078  0 22  ARG A CB    1 ? ? 
ATOM   132  C CG    . ARG A 1 41  ? -9.974  31.120 58.363 1.000 34.329  0 22  ARG A CG    1 ? ? 
ATOM   133  C CD    . ARG A 1 41  ? -8.934  31.659 59.315 1.000 40.306  0 22  ARG A CD    1 ? ? 
ATOM   134  N NE    . ARG A 1 41  ? -7.549  31.550 58.851 1.000 43.156  0 22  ARG A NE    1 ? ? 
ATOM   135  C CZ    . ARG A 1 41  ? -6.524  32.282 59.286 1.000 42.367  0 22  ARG A CZ    1 ? ? 
ATOM   136  N NH1   . ARG A 1 41  ? -6.702  33.214 60.208 1.000 41.855  0 22  ARG A NH1   1 ? ? 
ATOM   137  N NH2   . ARG A 1 41  ? -5.318  32.081 58.784 1.000 42.022  0 22  ARG A NH2   1 ? ? 
ATOM   138  N N     . LYS A 1 42  ? -12.993 28.710 60.201 1.000 32.848  0 23  LYS A N     1 ? ? 
ATOM   139  C CA    . LYS A 1 42  ? -13.039 27.476 60.971 1.000 33.994  0 23  LYS A CA    1 ? ? 
ATOM   140  C C     . LYS A 1 42  ? -13.392 26.301 60.052 1.000 31.543  0 23  LYS A C     1 ? ? 
ATOM   141  O O     . LYS A 1 42  ? -12.545 25.430 59.844 1.000 29.985  0 23  LYS A O     1 ? ? 
ATOM   142  C CB    . LYS A 1 42  ? -13.993 27.592 62.156 1.000 36.391  0 23  LYS A CB    1 ? ? 
ATOM   143  C CG    . LYS A 1 42  ? -13.987 26.356 63.033 1.000 38.638  0 23  LYS A CG    1 ? ? 
ATOM   144  C CD    . LYS A 1 42  ? -14.871 26.537 64.219 1.000 42.141  0 23  LYS A CD    1 ? ? 
ATOM   145  C CE    . LYS A 1 42  ? -15.275 25.213 64.832 1.000 44.448  0 23  LYS A CE    1 ? ? 
ATOM   146  N NZ    . LYS A 1 42  ? -16.505 25.370 65.647 1.000 43.020  0 23  LYS A NZ    1 ? ? 
ATOM   147  N N     . GLU A 1 43  ? -14.574 26.357 59.415 1.000 29.566  0 24  GLU A N     1 ? ? 
ATOM   148  C CA    . GLU A 1 43  ? -15.070 25.351 58.483 1.000 30.579  0 24  GLU A CA    1 ? ? 
ATOM   149  C C     . GLU A 1 43  ? -14.060 25.055 57.372 1.000 30.145  0 24  GLU A C     1 ? ? 
ATOM   150  O O     . GLU A 1 43  ? -13.868 23.903 57.000 1.000 28.632  0 24  GLU A O     1 ? ? 
ATOM   151  C CB    . GLU A 1 43  ? -16.388 25.815 57.862 1.000 32.702  0 24  GLU A CB    1 ? ? 
ATOM   152  C CG    . GLU A 1 43  ? -17.554 25.776 58.839 1.000 35.668  0 24  GLU A CG    1 ? ? 
ATOM   153  C CD    . GLU A 1 43  ? -18.745 26.655 58.496 1.000 40.638  0 24  GLU A CD    1 ? ? 
ATOM   154  O OE1   . GLU A 1 43  ? -18.920 26.962 57.301 1.000 39.262  0 24  GLU A OE1   1 ? ? 
ATOM   155  O OE2   . GLU A 1 43  ? -19.429 27.125 59.438 1.000 43.245  0 24  GLU A OE2   1 ? ? 
ATOM   156  N N     . PHE A 1 44  ? -13.439 26.104 56.827 1.000 28.661  0 25  PHE A N     1 ? ? 
ATOM   157  C CA    . PHE A 1 44  ? -12.416 25.966 55.805 1.000 27.068  0 25  PHE A CA    1 ? ? 
ATOM   158  C C     . PHE A 1 44  ? -11.219 25.159 56.292 1.000 27.229  0 25  PHE A C     1 ? ? 
ATOM   159  O O     . PHE A 1 44  ? -10.674 24.372 55.527 1.000 28.174  0 25  PHE A O     1 ? ? 
ATOM   160  C CB    . PHE A 1 44  ? -11.899 27.349 55.404 1.000 25.142  0 25  PHE A CB    1 ? ? 
ATOM   161  C CG    . PHE A 1 44  ? -10.844 27.345 54.335 1.000 22.769  0 25  PHE A CG    1 ? ? 
ATOM   162  C CD1   . PHE A 1 44  ? -11.199 27.260 53.000 1.000 22.855  0 25  PHE A CD1   1 ? ? 
ATOM   163  C CD2   . PHE A 1 44  ? -9.505  27.422 54.668 1.000 21.770  0 25  PHE A CD2   1 ? ? 
ATOM   164  C CE1   . PHE A 1 44  ? -10.232 27.263 52.005 1.000 21.920  0 25  PHE A CE1   1 ? ? 
ATOM   165  C CE2   . PHE A 1 44  ? -8.539  27.432 53.681 1.000 21.276  0 25  PHE A CE2   1 ? ? 
ATOM   166  C CZ    . PHE A 1 44  ? -8.902  27.341 52.353 1.000 22.071  0 25  PHE A CZ    1 ? ? 
ATOM   167  N N     . ASP A 1 45  ? -10.743 25.441 57.506 1.000 28.339  0 26  ASP A N     1 ? ? 
ATOM   168  C CA    . ASP A 1 45  ? -9.517  24.821 57.981 1.000 29.190  0 26  ASP A CA    1 ? ? 
ATOM   169  C C     . ASP A 1 45  ? -9.739  23.331 58.205 1.000 28.681  0 26  ASP A C     1 ? ? 
ATOM   170  O O     . ASP A 1 45  ? -8.871  22.537 57.876 1.000 30.498  0 26  ASP A O     1 ? ? 
ATOM   171  C CB    . ASP A 1 45  ? -8.930  25.577 59.170 1.000 32.319  0 26  ASP A CB    1 ? ? 
ATOM   172  C CG    . ASP A 1 45  ? -7.916  26.629 58.734 1.000 35.056  0 26  ASP A CG    1 ? ? 
ATOM   173  O OD1   . ASP A 1 45  ? -7.280  26.439 57.651 1.000 36.169  0 26  ASP A OD1   1 ? ? 
ATOM   174  O OD2   . ASP A 1 45  ? -7.751  27.616 59.475 1.000 36.056  0 26  ASP A OD2   1 ? ? 
ATOM   175  N N     . LEU A 1 46  ? -10.913 22.967 58.717 1.000 27.660  0 27  LEU A N     1 ? ? 
ATOM   176  C CA    . LEU A 1 46  ? -11.305 21.576 58.859 1.000 26.656  0 27  LEU A CA    1 ? ? 
ATOM   177  C C     . LEU A 1 46  ? -11.474 20.916 57.486 1.000 26.570  0 27  LEU A C     1 ? ? 
ATOM   178  O O     . LEU A 1 46  ? -10.977 19.804 57.207 1.000 25.815  0 27  LEU A O     1 ? ? 
ATOM   179  C CB    . LEU A 1 46  ? -12.594 21.537 59.696 1.000 26.983  0 27  LEU A CB    1 ? ? 
ATOM   180  C CG    . LEU A 1 46  ? -12.375 21.650 61.209 1.000 28.460  0 27  LEU A CG    1 ? ? 
ATOM   181  C CD1   . LEU A 1 46  ? -13.635 22.056 61.968 1.000 26.955  0 27  LEU A CD1   1 ? ? 
ATOM   182  C CD2   . LEU A 1 46  ? -11.806 20.346 61.753 1.000 29.020  0 27  LEU A CD2   1 ? ? 
ATOM   183  N N     . TYR A 1 47  ? -12.134 21.655 56.598 1.000 24.319  0 28  TYR A N     1 ? ? 
ATOM   184  C CA    . TYR A 1 47  ? -12.452 21.061 55.322 1.000 24.775  0 28  TYR A CA    1 ? ? 
ATOM   185  C C     . TYR A 1 47  ? -11.181 20.762 54.543 1.000 26.629  0 28  TYR A C     1 ? ? 
ATOM   186  O O     . TYR A 1 47  ? -11.115 19.743 53.859 1.000 25.808  0 28  TYR A O     1 ? ? 
ATOM   187  C CB    . TYR A 1 47  ? -13.407 21.938 54.519 1.000 23.382  0 28  TYR A CB    1 ? ? 
ATOM   188  C CG    . TYR A 1 47  ? -13.608 21.488 53.096 1.000 23.291  0 28  TYR A CG    1 ? ? 
ATOM   189  C CD1   . TYR A 1 47  ? -14.335 20.345 52.785 1.000 22.156  0 28  TYR A CD1   1 ? ? 
ATOM   190  C CD2   . TYR A 1 47  ? -13.073 22.222 52.058 1.000 22.631  0 28  TYR A CD2   1 ? ? 
ATOM   191  C CE1   . TYR A 1 47  ? -14.581 19.972 51.471 1.000 21.533  0 28  TYR A CE1   1 ? ? 
ATOM   192  C CE2   . TYR A 1 47  ? -13.258 21.841 50.745 1.000 22.366  0 28  TYR A CE2   1 ? ? 
ATOM   193  C CZ    . TYR A 1 47  ? -14.007 20.713 50.451 1.000 22.567  0 28  TYR A CZ    1 ? ? 
ATOM   194  O OH    . TYR A 1 47  ? -14.151 20.339 49.145 1.000 22.847  0 28  TYR A OH    1 ? ? 
ATOM   195  N N     . LYS A 1 48  ? -10.193 21.662 54.632 1.000 27.239  0 29  LYS A N     1 ? ? 
ATOM   196  C CA    . LYS A 1 48  ? -9.139  21.656 53.629 1.000 29.420  0 29  LYS A CA    1 ? ? 
ATOM   197  C C     . LYS A 1 48  ? -8.342  20.360 53.652 1.000 30.606  0 29  LYS A C     1 ? ? 
ATOM   198  O O     . LYS A 1 48  ? -7.747  19.983 52.647 1.000 30.778  0 29  LYS A O     1 ? ? 
ATOM   199  C CB    . LYS A 1 48  ? -8.210  22.866 53.707 1.000 31.312  0 29  LYS A CB    1 ? ? 
ATOM   200  C CG    . LYS A 1 48  ? -7.306  22.906 54.917 1.000 33.231  0 29  LYS A CG    1 ? ? 
ATOM   201  C CD    . LYS A 1 48  ? -6.729  24.270 55.083 1.000 36.088  0 29  LYS A CD    1 ? ? 
ATOM   202  C CE    . LYS A 1 48  ? -5.253  24.348 55.320 1.000 39.519  0 29  LYS A CE    1 ? ? 
ATOM   203  N NZ    . LYS A 1 48  ? -4.887  25.311 56.378 1.000 42.301  0 29  LYS A NZ    1 ? ? 
ATOM   204  N N     . LYS A 1 49  ? -8.332  19.671 54.795 1.000 31.684  0 30  LYS A N     1 ? ? 
ATOM   205  C CA    . LYS A 1 49  ? -7.507  18.478 54.908 1.000 27.677  0 30  LYS A CA    1 ? ? 
ATOM   206  C C     . LYS A 1 49  ? -8.347  17.243 55.185 1.000 26.455  0 30  LYS A C     1 ? ? 
ATOM   207  O O     . LYS A 1 49  ? -7.780  16.181 55.442 1.000 29.114  0 30  LYS A O     1 ? ? 
ATOM   208  C CB    . LYS A 1 49  ? -6.469  18.638 56.016 1.000 28.089  0 30  LYS A CB    1 ? ? 
ATOM   209  C CG    . LYS A 1 49  ? -5.433  19.713 55.742 1.000 29.679  0 30  LYS A CG    1 ? ? 
ATOM   210  C CD    . LYS A 1 49  ? -4.472  19.903 56.857 1.000 29.866  0 30  LYS A CD    1 ? ? 
ATOM   211  C CE    . LYS A 1 49  ? -3.328  20.791 56.414 1.000 30.690  0 30  LYS A CE    1 ? ? 
ATOM   212  N NZ    . LYS A 1 49  ? -2.075  20.409 57.123 1.000 28.999  0 30  LYS A NZ    1 ? ? 
ATOM   213  N N     . SER A 1 50  ? -9.673  17.371 55.093 1.000 23.508  0 31  SER A N     1 ? ? 
ATOM   214  C CA    . SER A 1 50  ? -10.545 16.253 55.393 1.000 22.687  0 31  SER A CA    1 ? ? 
ATOM   215  C C     . SER A 1 50  ? -10.324 15.159 54.364 1.000 22.929  0 31  SER A C     1 ? ? 
ATOM   216  O O     . SER A 1 50  ? -10.615 15.385 53.188 1.000 22.448  0 31  SER A O     1 ? ? 
ATOM   217  C CB    . SER A 1 50  ? -11.982 16.684 55.396 1.000 22.542  0 31  SER A CB    1 ? ? 
ATOM   218  O OG    . SER A 1 50  ? -12.838 15.636 55.828 1.000 21.869  0 31  SER A OG    1 ? ? 
ATOM   219  N N     . GLY A 1 51  ? -9.826  14.004 54.842 1.000 22.483  0 32  GLY A N     1 ? ? 
ATOM   220  C CA    . GLY A 1 51  ? -9.677  12.790 54.058 1.000 22.372  0 32  GLY A CA    1 ? ? 
ATOM   221  C C     . GLY A 1 51  ? -8.555  12.814 53.011 1.000 21.807  0 32  GLY A C     1 ? ? 
ATOM   222  O O     . GLY A 1 51  ? -8.443  11.887 52.223 1.000 20.518  0 32  GLY A O     1 ? ? 
ATOM   223  N N     . ILE A 1 52  ? -7.728  13.866 52.997 1.000 22.805  0 33  ILE A N     1 ? ? 
ATOM   224  C CA    . ILE A 1 52  ? -6.576  13.953 52.110 1.000 23.483  0 33  ILE A CA    1 ? ? 
ATOM   225  C C     . ILE A 1 52  ? -5.441  13.096 52.666 1.000 22.785  0 33  ILE A C     1 ? ? 
ATOM   226  O O     . ILE A 1 52  ? -5.538  12.524 53.747 1.000 23.160  0 33  ILE A O     1 ? ? 
ATOM   227  C CB    . ILE A 1 52  ? -6.130  15.420 51.912 1.000 25.009  0 33  ILE A CB    1 ? ? 
ATOM   228  C CG1   . ILE A 1 52  ? -5.187  15.917 53.018 1.000 24.899  0 33  ILE A CG1   1 ? ? 
ATOM   229  C CG2   . ILE A 1 52  ? -7.345  16.332 51.739 1.000 24.395  0 33  ILE A CG2   1 ? ? 
ATOM   230  C CD1   . ILE A 1 52  ? -4.455  17.213 52.672 1.000 25.782  0 33  ILE A CD1   1 ? ? 
ATOM   231  N N     . THR A 1 53  ? -4.352  13.030 51.901 1.000 22.906  0 34  THR A N     1 ? ? 
ATOM   232  C CA    . THR A 1 53  ? -3.115  12.412 52.344 1.000 21.934  0 34  THR A CA    1 ? ? 
ATOM   233  C C     . THR A 1 53  ? -2.117  13.535 52.574 1.000 22.569  0 34  THR A C     1 ? ? 
ATOM   234  O O     . THR A 1 53  ? -2.138  14.505 51.836 1.000 23.972  0 34  THR A O     1 ? ? 
ATOM   235  C CB    . THR A 1 53  ? -2.629  11.374 51.329 1.000 21.065  0 34  THR A CB    1 ? ? 
ATOM   236  O OG1   . THR A 1 53  ? -3.638  10.363 51.346 1.000 20.080  0 34  THR A OG1   1 ? ? 
ATOM   237  C CG2   . THR A 1 53  ? -1.334  10.717 51.750 1.000 20.466  0 34  THR A CG2   1 ? ? 
ATOM   238  N N     . GLU A 1 54  ? -1.253  13.401 53.586 1.000 22.157  0 35  GLU A N     1 ? ? 
ATOM   239  C CA    . GLU A 1 54  ? -0.226  14.408 53.767 1.000 21.797  0 35  GLU A CA    1 ? ? 
ATOM   240  C C     . GLU A 1 54  ? 1.002   13.807 54.425 1.000 21.637  0 35  GLU A C     1 ? ? 
ATOM   241  O O     . GLU A 1 54  ? 0.908   12.852 55.194 1.000 20.578  0 35  GLU A O     1 ? ? 
ATOM   242  C CB    . GLU A 1 54  ? -0.753  15.674 54.441 1.000 23.126  0 35  GLU A CB    1 ? ? 
ATOM   243  C CG    . GLU A 1 54  ? -0.635  15.675 55.936 1.000 24.460  0 35  GLU A CG    1 ? ? 
ATOM   244  C CD    . GLU A 1 54  ? -0.905  16.967 56.687 1.000 25.564  0 35  GLU A CD    1 ? ? 
ATOM   245  O OE1   . GLU A 1 54  ? -0.557  16.967 57.870 1.000 26.934  0 35  GLU A OE1   1 ? ? 
ATOM   246  O OE2   . GLU A 1 54  ? -1.470  17.941 56.126 1.000 24.253  0 35  GLU A OE2   1 ? ? 
ATOM   247  N N     . VAL A 1 55  ? 2.146   14.402 54.096 1.000 20.157  0 36  VAL A N     1 ? ? 
ATOM   248  C CA    . VAL A 1 55  ? 3.379   13.939 54.678 1.000 20.120  0 36  VAL A CA    1 ? ? 
ATOM   249  C C     . VAL A 1 55  ? 3.641   14.714 55.954 1.000 21.100  0 36  VAL A C     1 ? ? 
ATOM   250  O O     . VAL A 1 55  ? 3.198   15.853 56.106 1.000 21.329  0 36  VAL A O     1 ? ? 
ATOM   251  C CB    . VAL A 1 55  ? 4.544   14.006 53.682 1.000 19.297  0 36  VAL A CB    1 ? ? 
ATOM   252  C CG1   . VAL A 1 55  ? 4.260   13.142 52.478 1.000 18.797  0 36  VAL A CG1   1 ? ? 
ATOM   253  C CG2   . VAL A 1 55  ? 4.883   15.408 53.259 1.000 18.423  0 36  VAL A CG2   1 ? ? 
ATOM   254  N N     . ASP A 1 56  ? 4.322   14.036 56.879 1.000 21.955  0 37  ASP A N     1 ? ? 
ATOM   255  C CA    . ASP A 1 56  ? 4.691   14.634 58.141 1.000 21.969  0 37  ASP A CA    1 ? ? 
ATOM   256  C C     . ASP A 1 56  ? 5.982   15.428 57.953 1.000 23.251  0 37  ASP A C     1 ? ? 
ATOM   257  O O     . ASP A 1 56  ? 7.066   14.862 57.780 1.000 25.684  0 37  ASP A O     1 ? ? 
ATOM   258  C CB    . ASP A 1 56  ? 4.834   13.574 59.221 1.000 23.515  0 37  ASP A CB    1 ? ? 
ATOM   259  C CG    . ASP A 1 56  ? 4.901   14.183 60.612 1.000 26.075  0 37  ASP A CG    1 ? ? 
ATOM   260  O OD1   . ASP A 1 56  ? 4.928   15.415 60.733 1.000 27.234  0 37  ASP A OD1   1 ? ? 
ATOM   261  O OD2   . ASP A 1 56  ? 5.003   13.441 61.567 1.000 27.788  0 37  ASP A OD2   1 ? ? 
ATOM   262  N N     . ARG A 1 57  ? 5.858   16.749 58.042 1.000 21.786  0 38  ARG A N     1 ? ? 
ATOM   263  C CA    . ARG A 1 57  ? 6.965   17.633 57.740 1.000 22.260  0 38  ARG A CA    1 ? ? 
ATOM   264  C C     . ARG A 1 57  ? 7.712   18.053 59.004 1.000 22.734  0 38  ARG A C     1 ? ? 
ATOM   265  O O     . ARG A 1 57  ? 8.654   18.839 58.910 1.000 23.136  0 38  ARG A O     1 ? ? 
ATOM   266  C CB    . ARG A 1 57  ? 6.453   18.859 56.975 1.000 21.247  0 38  ARG A CB    1 ? ? 
ATOM   267  C CG    . ARG A 1 57  ? 5.943   18.535 55.573 1.000 21.423  0 38  ARG A CG    1 ? ? 
ATOM   268  C CD    . ARG A 1 57  ? 7.063   18.405 54.549 1.000 21.346  0 38  ARG A CD    1 ? ? 
ATOM   269  N NE    . ARG A 1 57  ? 7.854   19.609 54.434 1.000 20.018  0 38  ARG A NE    1 ? ? 
ATOM   270  C CZ    . ARG A 1 57  ? 9.128   19.650 54.099 1.000 19.167  0 38  ARG A CZ    1 ? ? 
ATOM   271  N NH1   . ARG A 1 57  ? 9.800   18.543 53.827 1.000 18.145  0 38  ARG A NH1   1 ? ? 
ATOM   272  N NH2   . ARG A 1 57  ? 9.723   20.822 54.013 1.000 20.409  0 38  ARG A NH2   1 ? ? 
ATOM   273  N N     . THR A 1 58  ? 7.330   17.518 60.167 1.000 22.636  0 39  THR A N     1 ? ? 
ATOM   274  C CA    . THR A 1 58  ? 7.886   17.984 61.427 1.000 24.272  0 39  THR A CA    1 ? ? 
ATOM   275  C C     . THR A 1 58  ? 9.413   17.882 61.441 1.000 25.291  0 39  THR A C     1 ? ? 
ATOM   276  O O     . THR A 1 58  ? 10.103  18.877 61.696 1.000 26.144  0 39  THR A O     1 ? ? 
ATOM   277  C CB    . THR A 1 58  ? 7.269   17.240 62.610 1.000 24.125  0 39  THR A CB    1 ? ? 
ATOM   278  O OG1   . THR A 1 58  ? 5.865   17.441 62.488 1.000 24.998  0 39  THR A OG1   1 ? ? 
ATOM   279  C CG2   . THR A 1 58  ? 7.744   17.776 63.939 1.000 22.712  0 39  THR A CG2   1 ? ? 
ATOM   280  N N     . GLU A 1 59  ? 9.929   16.672 61.182 1.000 24.203  0 40  GLU A N     1 ? ? 
ATOM   281  C CA    . GLU A 1 59  ? 11.369  16.449 61.202 1.000 25.249  0 40  GLU A CA    1 ? ? 
ATOM   282  C C     . GLU A 1 59  ? 12.084  17.410 60.248 1.000 24.816  0 40  GLU A C     1 ? ? 
ATOM   283  O O     . GLU A 1 59  ? 13.081  18.034 60.631 1.000 23.766  0 40  GLU A O     1 ? ? 
ATOM   284  C CB    . GLU A 1 59  ? 11.659  14.984 60.877 1.000 27.286  0 40  GLU A CB    1 ? ? 
ATOM   285  C CG    . GLU A 1 59  ? 13.135  14.606 60.896 1.000 29.512  0 40  GLU A CG    1 ? ? 
ATOM   286  C CD    . GLU A 1 59  ? 13.436  13.140 60.595 1.000 30.763  0 40  GLU A CD    1 ? ? 
ATOM   287  O OE1   . GLU A 1 59  ? 12.482  12.311 60.589 1.000 31.465  0 40  GLU A OE1   1 ? ? 
ATOM   288  O OE2   . GLU A 1 59  ? 14.626  12.822 60.363 1.000 29.162  0 40  GLU A OE2   1 ? ? 
ATOM   289  N N     . ALA A 1 60  ? 11.559  17.517 59.012 1.000 23.447  0 41  ALA A N     1 ? ? 
ATOM   290  C CA    . ALA A 1 60  ? 12.165  18.333 57.968 1.000 22.478  0 41  ALA A CA    1 ? ? 
ATOM   291  C C     . ALA A 1 60  ? 12.125  19.809 58.353 1.000 23.510  0 41  ALA A C     1 ? ? 
ATOM   292  O O     . ALA A 1 60  ? 13.099  20.536 58.151 1.000 22.058  0 41  ALA A O     1 ? ? 
ATOM   293  C CB    . ALA A 1 60  ? 11.479  18.111 56.646 1.000 22.829  0 41  ALA A CB    1 ? ? 
ATOM   294  N N     . LYS A 1 61  ? 11.003  20.240 58.939 1.000 25.439  0 42  LYS A N     1 ? ? 
ATOM   295  C CA    . LYS A 1 61  ? 10.875  21.644 59.290 1.000 27.659  0 42  LYS A CA    1 ? ? 
ATOM   296  C C     . LYS A 1 61  ? 11.866  22.021 60.379 1.000 29.154  0 42  LYS A C     1 ? ? 
ATOM   297  O O     . LYS A 1 61  ? 12.337  23.150 60.408 1.000 32.377  0 42  LYS A O     1 ? ? 
ATOM   298  C CB    . LYS A 1 61  ? 9.449   22.009 59.694 1.000 27.503  0 42  LYS A CB    1 ? ? 
ATOM   299  C CG    . LYS A 1 61  ? 8.579   22.476 58.531 1.000 27.227  0 42  LYS A CG    1 ? ? 
ATOM   300  C CD    . LYS A 1 61  ? 7.250   23.011 59.009 1.000 26.528  0 42  LYS A CD    1 ? ? 
ATOM   301  C CE    . LYS A 1 61  ? 6.117   22.014 58.912 1.000 27.246  0 42  LYS A CE    1 ? ? 
ATOM   302  N NZ    . LYS A 1 61  ? 5.272   22.018 60.130 1.000 26.994  0 42  LYS A NZ    1 ? ? 
ATOM   303  N N     . GLU A 1 62  ? 12.181  21.078 61.258 1.000 28.712  0 43  GLU A N     1 ? ? 
ATOM   304  C CA    . GLU A 1 62  ? 13.124  21.396 62.312 1.000 31.281  0 43  GLU A CA    1 ? ? 
ATOM   305  C C     . GLU A 1 62  ? 14.565  21.410 61.796 1.000 30.023  0 43  GLU A C     1 ? ? 
ATOM   306  O O     . GLU A 1 62  ? 15.356  22.285 62.147 1.000 31.171  0 43  GLU A O     1 ? ? 
ATOM   307  C CB    . GLU A 1 62  ? 12.936  20.388 63.430 1.000 33.197  0 43  GLU A CB    1 ? ? 
ATOM   308  C CG    . GLU A 1 62  ? 13.338  20.927 64.747 1.000 36.013  0 43  GLU A CG    1 ? ? 
ATOM   309  C CD    . GLU A 1 62  ? 13.121  19.976 65.913 1.000 40.251  0 43  GLU A CD    1 ? ? 
ATOM   310  O OE1   . GLU A 1 62  ? 13.927  20.100 66.871 1.000 37.588  0 43  GLU A OE1   1 ? ? 
ATOM   311  O OE2   . GLU A 1 62  ? 12.165  19.137 65.886 1.000 41.039  0 43  GLU A OE2   1 ? ? 
ATOM   312  N N     . GLY A 1 63  ? 14.908  20.419 60.977 1.000 28.649  0 44  GLY A N     1 ? ? 
ATOM   313  C CA    . GLY A 1 63  ? 16.239  20.386 60.404 1.000 27.660  0 44  GLY A CA    1 ? ? 
ATOM   314  C C     . GLY A 1 63  ? 16.510  21.606 59.532 1.000 26.870  0 44  GLY A C     1 ? ? 
ATOM   315  O O     . GLY A 1 63  ? 17.620  22.132 59.540 1.000 26.269  0 44  GLY A O     1 ? ? 
ATOM   316  N N     . LEU A 1 64  ? 15.507  22.032 58.759 1.000 27.273  0 45  LEU A N     1 ? ? 
ATOM   317  C CA    . LEU A 1 64  ? 15.693  23.175 57.876 1.000 28.464  0 45  LEU A CA    1 ? ? 
ATOM   318  C C     . LEU A 1 64  ? 15.889  24.447 58.685 1.000 29.836  0 45  LEU A C     1 ? ? 
ATOM   319  O O     . LEU A 1 64  ? 16.714  25.281 58.320 1.000 27.811  0 45  LEU A O     1 ? ? 
ATOM   320  C CB    . LEU A 1 64  ? 14.509  23.337 56.924 1.000 26.172  0 45  LEU A CB    1 ? ? 
ATOM   321  C CG    . LEU A 1 64  ? 14.454  22.293 55.818 1.000 24.727  0 45  LEU A CG    1 ? ? 
ATOM   322  C CD1   . LEU A 1 64  ? 13.094  22.354 55.147 1.000 24.006  0 45  LEU A CD1   1 ? ? 
ATOM   323  C CD2   . LEU A 1 64  ? 15.570  22.489 54.810 1.000 23.122  0 45  LEU A CD2   1 ? ? 
ATOM   324  N N     . LYS A 1 65  ? 15.185  24.539 59.815 1.000 32.920  0 46  LYS A N     1 ? ? 
ATOM   325  C CA    . LYS A 1 65  ? 15.290  25.692 60.690 1.000 35.401  0 46  LYS A CA    1 ? ? 
ATOM   326  C C     . LYS A 1 65  ? 16.713  25.827 61.227 1.000 37.372  0 46  LYS A C     1 ? ? 
ATOM   327  O O     . LYS A 1 65  ? 17.178  26.929 61.522 1.000 40.168  0 46  LYS A O     1 ? ? 
ATOM   328  C CB    . LYS A 1 65  ? 14.307  25.474 61.834 1.000 39.781  0 46  LYS A CB    1 ? ? 
ATOM   329  C CG    . LYS A 1 65  ? 13.963  26.704 62.644 1.000 45.099  0 46  LYS A CG    1 ? ? 
ATOM   330  C CD    . LYS A 1 65  ? 12.577  26.574 63.238 1.000 47.999  0 46  LYS A CD    1 ? ? 
ATOM   331  C CE    . LYS A 1 65  ? 12.379  27.303 64.556 1.000 51.735  0 46  LYS A CE    1 ? ? 
ATOM   332  N NZ    . LYS A 1 65  ? 12.589  26.415 65.725 1.000 49.863  0 46  LYS A NZ    1 ? ? 
ATOM   333  N N     . ARG A 1 66  ? 17.416  24.696 61.310 1.000 37.327  0 47  ARG A N     1 ? ? 
ATOM   334  C CA    . ARG A 1 66  ? 18.789  24.653 61.789 1.000 34.287  0 47  ARG A CA    1 ? ? 
ATOM   335  C C     . ARG A 1 66  ? 19.780  24.658 60.622 1.000 32.311  0 47  ARG A C     1 ? ? 
ATOM   336  O O     . ARG A 1 66  ? 20.971  24.437 60.825 1.000 32.068  0 47  ARG A O     1 ? ? 
ATOM   337  C CB    . ARG A 1 66  ? 18.986  23.400 62.640 1.000 36.126  0 47  ARG A CB    1 ? ? 
ATOM   338  C CG    . ARG A 1 66  ? 18.182  23.413 63.935 1.000 41.317  0 47  ARG A CG    1 ? ? 
ATOM   339  C CD    . ARG A 1 66  ? 18.393  22.179 64.793 1.000 44.313  0 47  ARG A CD    1 ? ? 
ATOM   340  N NE    . ARG A 1 66  ? 19.824  21.922 64.796 1.000 44.536  0 47  ARG A NE    1 ? ? 
ATOM   341  C CZ    . ARG A 1 66  ? 20.676  22.272 65.757 1.000 41.287  0 47  ARG A CZ    1 ? ? 
ATOM   342  N NH1   . ARG A 1 66  ? 21.956  22.016 65.585 1.000 39.478  0 47  ARG A NH1   1 ? ? 
ATOM   343  N NH2   . ARG A 1 66  ? 20.269  22.851 66.880 1.000 39.798  0 47  ARG A NH2   1 ? ? 
ATOM   344  N N     . GLY A 1 67  ? 19.277  24.922 59.407 1.000 30.510  0 48  GLY A N     1 ? ? 
ATOM   345  C CA    . GLY A 1 67  ? 20.092  25.128 58.223 1.000 29.390  0 48  GLY A CA    1 ? ? 
ATOM   346  C C     . GLY A 1 67  ? 20.798  23.849 57.788 1.000 30.984  0 48  GLY A C     1 ? ? 
ATOM   347  O O     . GLY A 1 67  ? 21.926  23.916 57.300 1.000 32.547  0 48  GLY A O     1 ? ? 
ATOM   348  N N     . GLU A 1 68  ? 20.165  22.697 58.049 1.000 30.058  0 49  GLU A N     1 ? ? 
ATOM   349  C CA    . GLU A 1 68  ? 20.664  21.432 57.527 1.000 29.970  0 49  GLU A CA    1 ? ? 
ATOM   350  C C     . GLU A 1 68  ? 20.371  21.361 56.031 1.000 28.222  0 49  GLU A C     1 ? ? 
ATOM   351  O O     . GLU A 1 68  ? 19.312  21.791 55.577 1.000 29.043  0 49  GLU A O     1 ? ? 
ATOM   352  C CB    . GLU A 1 68  ? 20.045  20.223 58.228 1.000 31.300  0 49  GLU A CB    1 ? ? 
ATOM   353  C CG    . GLU A 1 68  ? 20.289  20.193 59.716 1.000 34.721  0 49  GLU A CG    1 ? ? 
ATOM   354  C CD    . GLU A 1 68  ? 19.592  19.119 60.526 1.000 36.664  0 49  GLU A CD    1 ? ? 
ATOM   355  O OE1   . GLU A 1 68  ? 19.807  19.109 61.721 1.000 38.594  0 49  GLU A OE1   1 ? ? 
ATOM   356  O OE2   . GLU A 1 68  ? 18.829  18.321 59.987 1.000 34.015  0 49  GLU A OE2   1 ? ? 
ATOM   357  N N     . THR A 1 69  ? 21.330  20.797 55.293 1.000 26.978  0 50  THR A N     1 ? ? 
ATOM   358  C CA    . THR A 1 69  ? 21.314  20.823 53.840 1.000 25.464  0 50  THR A CA    1 ? ? 
ATOM   359  C C     . THR A 1 69  ? 21.260  19.417 53.256 1.000 23.721  0 50  THR A C     1 ? ? 
ATOM   360  O O     . THR A 1 69  ? 21.356  19.263 52.040 1.000 23.387  0 50  THR A O     1 ? ? 
ATOM   361  C CB    . THR A 1 69  ? 22.541  21.538 53.238 1.000 27.100  0 50  THR A CB    1 ? ? 
ATOM   362  O OG1   . THR A 1 69  ? 23.798  20.977 53.614 1.000 27.464  0 50  THR A OG1   1 ? ? 
ATOM   363  C CG2   . THR A 1 69  ? 22.549  23.032 53.477 1.000 26.940  0 50  THR A CG2   1 ? ? 
ATOM   364  N N     . THR A 1 70  ? 21.177  18.404 54.123 1.000 22.430  0 51  THR A N     1 ? ? 
ATOM   365  C CA    . THR A 1 70  ? 21.130  17.021 53.692 1.000 22.412  0 51  THR A CA    1 ? ? 
ATOM   366  C C     . THR A 1 70  ? 19.810  16.381 54.114 1.000 21.926  0 51  THR A C     1 ? ? 
ATOM   367  O O     . THR A 1 70  ? 19.267  16.709 55.156 1.000 23.686  0 51  THR A O     1 ? ? 
ATOM   368  C CB    . THR A 1 70  ? 22.352  16.252 54.210 1.000 22.529  0 51  THR A CB    1 ? ? 
ATOM   369  O OG1   . THR A 1 70  ? 22.557  16.436 55.616 1.000 22.620  0 51  THR A OG1   1 ? ? 
ATOM   370  C CG2   . THR A 1 70  ? 23.610  16.689 53.507 1.000 21.903  0 51  THR A CG2   1 ? ? 
ATOM   371  N N     . HIS A 1 71  ? 19.316  15.460 53.283 1.000 21.615  0 52  HIS A N     1 ? ? 
ATOM   372  C CA    . HIS A 1 71  ? 18.193  14.576 53.555 1.000 22.933  0 52  HIS A CA    1 ? ? 
ATOM   373  C C     . HIS A 1 71  ? 16.834  15.249 53.358 1.000 24.792  0 52  HIS A C     1 ? ? 
ATOM   374  O O     . HIS A 1 71  ? 15.958  14.649 52.738 1.000 26.335  0 52  HIS A O     1 ? ? 
ATOM   375  C CB    . HIS A 1 71  ? 18.297  13.921 54.934 1.000 21.643  0 52  HIS A CB    1 ? ? 
ATOM   376  C CG    . HIS A 1 71  ? 19.516  13.085 55.087 1.000 23.343  0 52  HIS A CG    1 ? ? 
ATOM   377  N ND1   . HIS A 1 71  ? 19.812  12.003 54.258 1.000 23.369  0 52  HIS A ND1   1 ? ? 
ATOM   378  C CD2   . HIS A 1 71  ? 20.535  13.170 55.964 1.000 23.865  0 52  HIS A CD2   1 ? ? 
ATOM   379  C CE1   . HIS A 1 71  ? 20.948  11.455 54.633 1.000 22.341  0 52  HIS A CE1   1 ? ? 
ATOM   380  N NE2   . HIS A 1 71  ? 21.423  12.171 55.657 1.000 24.306  0 52  HIS A NE2   1 ? ? 
ATOM   381  N N     . HIS A 1 72  ? 16.660  16.475 53.871 1.000 24.887  0 53  HIS A N     1 ? ? 
ATOM   382  C CA    . HIS A 1 72  ? 15.339  17.088 53.951 1.000 26.209  0 53  HIS A CA    1 ? ? 
ATOM   383  C C     . HIS A 1 72  ? 14.874  17.604 52.592 1.000 26.246  0 53  HIS A C     1 ? ? 
ATOM   384  O O     . HIS A 1 72  ? 15.666  18.175 51.841 1.000 27.577  0 53  HIS A O     1 ? ? 
ATOM   385  C CB    . HIS A 1 72  ? 15.346  18.252 54.947 1.000 27.265  0 53  HIS A CB    1 ? ? 
ATOM   386  C CG    . HIS A 1 72  ? 15.976  17.938 56.262 1.000 29.411  0 53  HIS A CG    1 ? ? 
ATOM   387  N ND1   . HIS A 1 72  ? 15.536  16.899 57.065 1.000 31.139  0 53  HIS A ND1   1 ? ? 
ATOM   388  C CD2   . HIS A 1 72  ? 17.002  18.529 56.916 1.000 29.323  0 53  HIS A CD2   1 ? ? 
ATOM   389  C CE1   . HIS A 1 72  ? 16.253  16.873 58.170 1.000 32.418  0 53  HIS A CE1   1 ? ? 
ATOM   390  N NE2   . HIS A 1 72  ? 17.181  17.852 58.088 1.000 32.178  0 53  HIS A NE2   1 ? ? 
ATOM   391  N N     . ALA A 1 73  ? 13.582  17.389 52.293 1.000 24.699  0 54  ALA A N     1 ? ? 
ATOM   392  C CA    . ALA A 1 73  ? 12.901  18.094 51.217 1.000 24.697  0 54  ALA A CA    1 ? ? 
ATOM   393  C C     . ALA A 1 73  ? 12.611  19.528 51.644 1.000 24.303  0 54  ALA A C     1 ? ? 
ATOM   394  O O     . ALA A 1 73  ? 12.170  19.773 52.765 1.000 25.554  0 54  ALA A O     1 ? ? 
ATOM   395  C CB    . ALA A 1 73  ? 11.599  17.415 50.863 1.000 24.660  0 54  ALA A CB    1 ? ? 
ATOM   396  N N     . VAL A 1 74  ? 12.791  20.475 50.722 1.000 23.159  0 55  VAL A N     1 ? ? 
ATOM   397  C CA    . VAL A 1 74  ? 12.637  21.878 51.067 1.000 21.576  0 55  VAL A CA    1 ? ? 
ATOM   398  C C     . VAL A 1 74  ? 11.161  22.240 51.219 1.000 22.232  0 55  VAL A C     1 ? ? 
ATOM   399  O O     . VAL A 1 74  ? 10.833  23.256 51.808 1.000 22.929  0 55  VAL A O     1 ? ? 
ATOM   400  C CB    . VAL A 1 74  ? 13.344  22.768 50.033 1.000 21.372  0 55  VAL A CB    1 ? ? 
ATOM   401  C CG1   . VAL A 1 74  ? 14.841  22.467 49.997 1.000 18.691  0 55  VAL A CG1   1 ? ? 
ATOM   402  C CG2   . VAL A 1 74  ? 12.710  22.670 48.639 1.000 19.158  0 55  VAL A CG2   1 ? ? 
ATOM   403  N N     . SER A 1 75  ? 10.260  21.382 50.737 1.000 21.669  0 56  SER A N     1 ? ? 
ATOM   404  C CA    . SER A 1 75  ? 8.838   21.670 50.748 1.000 20.948  0 56  SER A CA    1 ? ? 
ATOM   405  C C     . SER A 1 75  ? 8.076   20.359 50.636 1.000 20.692  0 56  SER A C     1 ? ? 
ATOM   406  O O     . SER A 1 75  ? 8.688   19.313 50.432 1.000 21.145  0 56  SER A O     1 ? ? 
ATOM   407  C CB    . SER A 1 75  ? 8.469   22.579 49.601 1.000 21.117  0 56  SER A CB    1 ? ? 
ATOM   408  O OG    . SER A 1 75  ? 8.509   21.879 48.366 1.000 20.755  0 56  SER A OG    1 ? ? 
ATOM   409  N N     . ARG A 1 76  ? 6.745   20.458 50.727 1.000 21.337  0 57  ARG A N     1 ? ? 
ATOM   410  C CA    . ARG A 1 76  ? 5.819   19.354 50.525 1.000 21.572  0 57  ARG A CA    1 ? ? 
ATOM   411  C C     . ARG A 1 76  ? 5.821   18.940 49.054 1.000 22.892  0 57  ARG A C     1 ? ? 
ATOM   412  O O     . ARG A 1 76  ? 5.192   17.942 48.692 1.000 26.302  0 57  ARG A O     1 ? ? 
ATOM   413  C CB    . ARG A 1 76  ? 4.398   19.750 50.941 1.000 20.428  0 57  ARG A CB    1 ? ? 
ATOM   414  C CG    . ARG A 1 76  ? 4.230   19.906 52.444 1.000 22.399  0 57  ARG A CG    1 ? ? 
ATOM   415  C CD    . ARG A 1 76  ? 2.796   20.165 52.880 1.000 22.984  0 57  ARG A CD    1 ? ? 
ATOM   416  N NE    . ARG A 1 76  ? 2.760   20.234 54.335 1.000 24.580  0 57  ARG A NE    1 ? ? 
ATOM   417  C CZ    . ARG A 1 76  ? 2.624   19.184 55.132 1.000 25.118  0 57  ARG A CZ    1 ? ? 
ATOM   418  N NH1   . ARG A 1 76  ? 2.620   19.327 56.437 1.000 23.986  0 57  ARG A NH1   1 ? ? 
ATOM   419  N NH2   . ARG A 1 76  ? 2.575   17.971 54.634 1.000 27.459  0 57  ARG A NH2   1 ? ? 
ATOM   420  N N     . GLY A 1 77  ? 6.517   19.707 48.208 1.000 20.807  0 58  GLY A N     1 ? ? 
ATOM   421  C CA    . GLY A 1 77  ? 6.476   19.489 46.772 1.000 20.860  0 58  GLY A CA    1 ? ? 
ATOM   422  C C     . GLY A 1 77  ? 7.250   18.251 46.328 1.000 20.799  0 58  GLY A C     1 ? ? 
ATOM   423  O O     . GLY A 1 77  ? 6.830   17.556 45.398 1.000 20.471  0 58  GLY A O     1 ? ? 
ATOM   424  N N     . SER A 1 78  ? 8.387   17.983 46.985 1.000 21.401  0 59  SER A N     1 ? ? 
ATOM   425  C CA    . SER A 1 78  ? 9.158   16.788 46.677 1.000 19.781  0 59  SER A CA    1 ? ? 
ATOM   426  C C     . SER A 1 78  ? 8.246   15.566 46.736 1.000 19.573  0 59  SER A C     1 ? ? 
ATOM   427  O O     . SER A 1 78  ? 8.119   14.855 45.739 1.000 21.283  0 59  SER A O     1 ? ? 
ATOM   428  C CB    . SER A 1 78  ? 10.348  16.638 47.578 1.000 19.599  0 59  SER A CB    1 ? ? 
ATOM   429  O OG    . SER A 1 78  ? 11.178  17.790 47.539 1.000 19.146  0 59  SER A OG    1 ? ? 
ATOM   430  N N     . ALA A 1 79  ? 7.546   15.407 47.867 1.000 18.364  0 60  ALA A N     1 ? ? 
ATOM   431  C CA    . ALA A 1 79  ? 6.668   14.263 48.062 1.000 18.040  0 60  ALA A CA    1 ? ? 
ATOM   432  C C     . ALA A 1 79  ? 5.550   14.255 47.027 1.000 17.216  0 60  ALA A C     1 ? ? 
ATOM   433  O O     . ALA A 1 79  ? 5.139   13.191 46.589 1.000 16.947  0 60  ALA A O     1 ? ? 
ATOM   434  C CB    . ALA A 1 79  ? 6.121   14.250 49.467 1.000 17.850  0 60  ALA A CB    1 ? ? 
ATOM   435  N N     . LYS A 1 80  ? 5.062   15.437 46.653 1.000 17.203  0 61  LYS A N     1 ? ? 
ATOM   436  C CA    . LYS A 1 80  ? 3.943   15.521 45.735 1.000 18.008  0 61  LYS A CA    1 ? ? 
ATOM   437  C C     . LYS A 1 80  ? 4.349   15.014 44.351 1.000 18.895  0 61  LYS A C     1 ? ? 
ATOM   438  O O     . LYS A 1 80  ? 3.611   14.245 43.723 1.000 18.334  0 61  LYS A O     1 ? ? 
ATOM   439  C CB    . LYS A 1 80  ? 3.442   16.962 45.684 1.000 17.916  0 61  LYS A CB    1 ? ? 
ATOM   440  C CG    . LYS A 1 80  ? 2.108   17.153 44.992 1.000 19.197  0 61  LYS A CG    1 ? ? 
ATOM   441  C CD    . LYS A 1 80  ? 1.666   18.580 45.194 1.000 19.263  0 61  LYS A CD    1 ? ? 
ATOM   442  C CE    . LYS A 1 80  ? 0.213   18.833 44.937 1.000 19.457  0 61  LYS A CE    1 ? ? 
ATOM   443  N NZ    . LYS A 1 80  ? 0.102   20.301 44.810 1.000 20.476  0 61  LYS A NZ    1 ? ? 
ATOM   444  N N     . LEU A 1 81  ? 5.512   15.473 43.865 1.000 19.050  0 62  LEU A N     1 ? ? 
ATOM   445  C CA    . LEU A 1 81  ? 5.957   15.023 42.560 1.000 19.281  0 62  LEU A CA    1 ? ? 
ATOM   446  C C     . LEU A 1 81  ? 6.287   13.532 42.621 1.000 20.338  0 62  LEU A C     1 ? ? 
ATOM   447  O O     . LEU A 1 81  ? 6.078   12.809 41.644 1.000 21.832  0 62  LEU A O     1 ? ? 
ATOM   448  C CB    . LEU A 1 81  ? 7.155   15.847 42.085 1.000 18.410  0 62  LEU A CB    1 ? ? 
ATOM   449  C CG    . LEU A 1 81  ? 7.757   15.463 40.724 1.000 18.146  0 62  LEU A CG    1 ? ? 
ATOM   450  C CD1   . LEU A 1 81  ? 6.766   15.563 39.588 1.000 17.160  0 62  LEU A CD1   1 ? ? 
ATOM   451  C CD2   . LEU A 1 81  ? 8.936   16.355 40.410 1.000 18.281  0 62  LEU A CD2   1 ? ? 
ATOM   452  N N     . GLN A 1 82  ? 6.796   13.076 43.769 1.000 19.734  0 63  GLN A N     1 ? ? 
ATOM   453  C CA    . GLN A 1 82  ? 7.197   11.686 43.872 1.000 20.703  0 63  GLN A CA    1 ? ? 
ATOM   454  C C     . GLN A 1 82  ? 5.986   10.788 43.632 1.000 19.982  0 63  GLN A C     1 ? ? 
ATOM   455  O O     . GLN A 1 82  ? 6.096   9.771  42.961 1.000 18.928  0 63  GLN A O     1 ? ? 
ATOM   456  C CB    . GLN A 1 82  ? 7.935   11.452 45.189 1.000 21.383  0 63  GLN A CB    1 ? ? 
ATOM   457  C CG    . GLN A 1 82  ? 7.780   10.057 45.713 1.000 22.463  0 63  GLN A CG    1 ? ? 
ATOM   458  C CD    . GLN A 1 82  ? 8.617   9.751  46.917 1.000 24.232  0 63  GLN A CD    1 ? ? 
ATOM   459  O OE1   . GLN A 1 82  ? 8.175   9.910  48.046 1.000 26.847  0 63  GLN A OE1   1 ? ? 
ATOM   460  N NE2   . GLN A 1 82  ? 9.800   9.215  46.666 1.000 24.860  0 63  GLN A NE2   1 ? ? 
ATOM   461  N N     . TRP A 1 83  ? 4.828   11.197 44.139 1.000 19.091  0 64  TRP A N     1 ? ? 
ATOM   462  C CA    . TRP A 1 83  ? 3.631   10.393 43.986 1.000 19.446  0 64  TRP A CA    1 ? ? 
ATOM   463  C C     . TRP A 1 83  ? 3.364   10.092 42.510 1.000 20.337  0 64  TRP A C     1 ? ? 
ATOM   464  O O     . TRP A 1 83  ? 2.909   8.992  42.181 1.000 21.450  0 64  TRP A O     1 ? ? 
ATOM   465  C CB    . TRP A 1 83  ? 2.451   11.102 44.642 1.000 19.150  0 64  TRP A CB    1 ? ? 
ATOM   466  C CG    . TRP A 1 83  ? 1.236   10.244 44.705 1.000 18.702  0 64  TRP A CG    1 ? ? 
ATOM   467  C CD1   . TRP A 1 83  ? 0.882   9.422  45.730 1.000 18.334  0 64  TRP A CD1   1 ? ? 
ATOM   468  C CD2   . TRP A 1 83  ? 0.228   10.100 43.693 1.000 18.303  0 64  TRP A CD2   1 ? ? 
ATOM   469  N NE1   . TRP A 1 83  ? -0.285  8.779  45.433 1.000 18.159  0 64  TRP A NE1   1 ? ? 
ATOM   470  C CE2   . TRP A 1 83  ? -0.700  9.160  44.185 1.000 18.083  0 64  TRP A CE2   1 ? ? 
ATOM   471  C CE3   . TRP A 1 83  ? 0.012   10.668 42.433 1.000 18.501  0 64  TRP A CE3   1 ? ? 
ATOM   472  C CZ2   . TRP A 1 83  ? -1.844  8.796  43.478 1.000 17.832  0 64  TRP A CZ2   1 ? ? 
ATOM   473  C CZ3   . TRP A 1 83  ? -1.112  10.303 41.727 1.000 17.877  0 64  TRP A CZ3   1 ? ? 
ATOM   474  C CH2   . TRP A 1 83  ? -2.030  9.390  42.250 1.000 18.107  0 64  TRP A CH2   1 ? ? 
ATOM   475  N N     . PHE A 1 84  ? 3.598   11.083 41.639 1.000 20.243  0 65  PHE A N     1 ? ? 
ATOM   476  C CA    . PHE A 1 84  ? 3.383   10.895 40.212 1.000 20.076  0 65  PHE A CA    1 ? ? 
ATOM   477  C C     . PHE A 1 84  ? 4.485   10.014 39.641 1.000 19.396  0 65  PHE A C     1 ? ? 
ATOM   478  O O     . PHE A 1 84  ? 4.229   9.175  38.787 1.000 20.446  0 65  PHE A O     1 ? ? 
ATOM   479  C CB    . PHE A 1 84  ? 3.379   12.219 39.435 1.000 19.803  0 65  PHE A CB    1 ? ? 
ATOM   480  C CG    . PHE A 1 84  ? 2.215   13.141 39.693 1.000 19.430  0 65  PHE A CG    1 ? ? 
ATOM   481  C CD1   . PHE A 1 84  ? 0.905   12.734 39.490 1.000 18.284  0 65  PHE A CD1   1 ? ? 
ATOM   482  C CD2   . PHE A 1 84  ? 2.442   14.437 40.129 1.000 19.251  0 65  PHE A CD2   1 ? ? 
ATOM   483  C CE1   . PHE A 1 84  ? -0.151  13.588 39.767 1.000 18.625  0 65  PHE A CE1   1 ? ? 
ATOM   484  C CE2   . PHE A 1 84  ? 1.380   15.292 40.387 1.000 19.005  0 65  PHE A CE2   1 ? ? 
ATOM   485  C CZ    . PHE A 1 84  ? 0.079   14.872 40.202 1.000 18.599  0 65  PHE A CZ    1 ? ? 
ATOM   486  N N     . VAL A 1 85  ? 5.723   10.268 40.054 1.000 19.021  0 66  VAL A N     1 ? ? 
ATOM   487  C CA    . VAL A 1 85  ? 6.855   9.586  39.459 1.000 19.938  0 66  VAL A CA    1 ? ? 
ATOM   488  C C     . VAL A 1 85  ? 6.788   8.092  39.805 1.000 21.210  0 66  VAL A C     1 ? ? 
ATOM   489  O O     . VAL A 1 85  ? 6.915   7.220  38.942 1.000 19.807  0 66  VAL A O     1 ? ? 
ATOM   490  C CB    . VAL A 1 85  ? 8.174   10.270 39.879 1.000 19.431  0 66  VAL A CB    1 ? ? 
ATOM   491  C CG1   . VAL A 1 85  ? 9.392   9.437  39.524 1.000 18.652  0 66  VAL A CG1   1 ? ? 
ATOM   492  C CG2   . VAL A 1 85  ? 8.299   11.660 39.265 1.000 19.366  0 66  VAL A CG2   1 ? ? 
ATOM   493  N N     . GLU A 1 86  ? 6.491   7.775  41.064 1.000 22.792  0 67  GLU A N     1 ? ? 
ATOM   494  C CA    . GLU A 1 86  ? 6.441   6.389  41.494 1.000 24.399  0 67  GLU A CA    1 ? ? 
ATOM   495  C C     . GLU A 1 86  ? 5.326   5.610  40.806 1.000 24.784  0 67  GLU A C     1 ? ? 
ATOM   496  O O     . GLU A 1 86  ? 5.338   4.393  40.841 1.000 27.470  0 67  GLU A O     1 ? ? 
ATOM   497  C CB    . GLU A 1 86  ? 6.391   6.311  43.014 1.000 25.843  0 67  GLU A CB    1 ? ? 
ATOM   498  C CG    . GLU A 1 86  ? 7.733   6.690  43.570 1.000 29.615  0 67  GLU A CG    1 ? ? 
ATOM   499  C CD    . GLU A 1 86  ? 7.877   6.769  45.082 1.000 33.943  0 67  GLU A CD    1 ? ? 
ATOM   500  O OE1   . GLU A 1 86  ? 6.830   6.807  45.791 1.000 34.558  0 67  GLU A OE1   1 ? ? 
ATOM   501  O OE2   . GLU A 1 86  ? 9.046   6.857  45.549 1.000 35.382  0 67  GLU A OE2   1 ? ? 
ATOM   502  N N     . ARG A 1 87  ? 4.407   6.303  40.134 1.000 25.304  0 68  ARG A N     1 ? ? 
ATOM   503  C CA    . ARG A 1 87  ? 3.328   5.651  39.409 1.000 23.998  0 68  ARG A CA    1 ? ? 
ATOM   504  C C     . ARG A 1 87  ? 3.529   5.782  37.902 1.000 22.929  0 68  ARG A C     1 ? ? 
ATOM   505  O O     . ARG A 1 87  ? 2.614   5.515  37.134 1.000 22.634  0 68  ARG A O     1 ? ? 
ATOM   506  C CB    . ARG A 1 87  ? 1.978   6.249  39.808 1.000 24.336  0 68  ARG A CB    1 ? ? 
ATOM   507  C CG    . ARG A 1 87  ? 1.381   5.647  41.077 1.000 26.037  0 68  ARG A CG    1 ? ? 
ATOM   508  C CD    . ARG A 1 87  ? 0.524   6.596  41.905 1.000 25.481  0 68  ARG A CD    1 ? ? 
ATOM   509  N NE    . ARG A 1 87  ? 0.290   6.015  43.223 1.000 27.248  0 68  ARG A NE    1 ? ? 
ATOM   510  C CZ    . ARG A 1 87  ? 1.116   6.151  44.259 1.000 28.166  0 68  ARG A CZ    1 ? ? 
ATOM   511  N NH1   . ARG A 1 87  ? 2.225   6.854  44.117 1.000 29.420  0 68  ARG A NH1   1 ? ? 
ATOM   512  N NH2   . ARG A 1 87  ? 0.840   5.591  45.426 1.000 27.140  0 68  ARG A NH2   1 ? ? 
ATOM   513  N N     . ASN A 1 88  ? 4.727   6.192  37.480 1.000 23.304  0 69  ASN A N     1 ? ? 
ATOM   514  C CA    . ASN A 1 88  ? 5.110   6.240  36.072 1.000 25.475  0 69  ASN A CA    1 ? ? 
ATOM   515  C C     . ASN A 1 88  ? 4.269   7.222  35.258 1.000 25.091  0 69  ASN A C     1 ? ? 
ATOM   516  O O     . ASN A 1 88  ? 4.263   7.162  34.031 1.000 25.051  0 69  ASN A O     1 ? ? 
ATOM   517  C CB    . ASN A 1 88  ? 5.091   4.863  35.405 1.000 26.358  0 69  ASN A CB    1 ? ? 
ATOM   518  C CG    . ASN A 1 88  ? 6.132   3.976  36.034 1.000 26.328  0 69  ASN A CG    1 ? ? 
ATOM   519  O OD1   . ASN A 1 88  ? 7.257   4.409  36.222 1.000 28.014  0 69  ASN A OD1   1 ? ? 
ATOM   520  N ND2   . ASN A 1 88  ? 5.765   2.761  36.399 1.000 26.866  0 69  ASN A ND2   1 ? ? 
ATOM   521  N N     . MET A 1 89  ? 3.588   8.146  35.935 1.000 24.237  0 70  MET A N     1 ? ? 
ATOM   522  C CA    . MET A 1 89  ? 2.779   9.102  35.207 1.000 24.625  0 70  MET A CA    1 ? ? 
ATOM   523  C C     . MET A 1 89  ? 3.688   10.112 34.496 1.000 24.326  0 70  MET A C     1 ? ? 
ATOM   524  O O     . MET A 1 89  ? 3.405   10.545 33.380 1.000 22.492  0 70  MET A O     1 ? ? 
ATOM   525  C CB    . MET A 1 89  ? 1.807   9.797  36.161 1.000 25.580  0 70  MET A CB    1 ? ? 
ATOM   526  C CG    . MET A 1 89  ? 0.711   8.868  36.625 1.000 26.047  0 70  MET A CG    1 ? ? 
ATOM   527  S SD    . MET A 1 89  ? -0.142  9.471  38.108 1.000 28.174  0 70  MET A SD    1 ? ? 
ATOM   528  C CE    . MET A 1 89  ? -1.152  8.050  38.512 1.000 23.569  0 70  MET A CE    1 ? ? 
ATOM   529  N N     . VAL A 1 90  ? 4.787   10.494 35.153 1.000 23.101  0 71  VAL A N     1 ? ? 
ATOM   530  C CA    . VAL A 1 90  ? 5.850   11.246 34.504 1.000 23.281  0 71  VAL A CA    1 ? ? 
ATOM   531  C C     . VAL A 1 90  ? 7.178   10.578 34.865 1.000 24.079  0 71  VAL A C     1 ? ? 
ATOM   532  O O     . VAL A 1 90  ? 7.364   10.142 36.006 1.000 23.420  0 71  VAL A O     1 ? ? 
ATOM   533  C CB    . VAL A 1 90  ? 5.821   12.749 34.859 1.000 23.697  0 71  VAL A CB    1 ? ? 
ATOM   534  C CG1   . VAL A 1 90  ? 5.895   12.984 36.361 1.000 22.728  0 71  VAL A CG1   1 ? ? 
ATOM   535  C CG2   . VAL A 1 90  ? 6.888   13.555 34.119 1.000 23.365  0 71  VAL A CG2   1 ? ? 
ATOM   536  N N     . ILE A 1 91  ? 8.064   10.440 33.872 1.000 24.440  0 72  ILE A N     1 ? ? 
ATOM   537  C CA    . ILE A 1 91  ? 9.332   9.767  34.098 1.000 25.912  0 72  ILE A CA    1 ? ? 
ATOM   538  C C     . ILE A 1 91  ? 10.448  10.741 33.769 1.000 27.174  0 72  ILE A C     1 ? ? 
ATOM   539  O O     . ILE A 1 91  ? 10.880  10.833 32.618 1.000 29.569  0 72  ILE A O     1 ? ? 
ATOM   540  C CB    . ILE A 1 91  ? 9.466   8.454  33.304 1.000 26.130  0 72  ILE A CB    1 ? ? 
ATOM   541  C CG1   . ILE A 1 91  ? 8.341   7.477  33.651 1.000 26.638  0 72  ILE A CG1   1 ? ? 
ATOM   542  C CG2   . ILE A 1 91  ? 10.812  7.799  33.568 1.000 25.697  0 72  ILE A CG2   1 ? ? 
ATOM   543  C CD1   . ILE A 1 91  ? 7.661   6.884  32.436 1.000 26.032  0 72  ILE A CD1   1 ? ? 
ATOM   544  N N     . PRO A 1 92  ? 10.914  11.515 34.770 1.000 26.403  0 73  PRO A N     1 ? ? 
ATOM   545  C CA    . PRO A 1 92  ? 11.932  12.534 34.522 1.000 27.177  0 73  PRO A CA    1 ? ? 
ATOM   546  C C     . PRO A 1 92  ? 13.209  11.914 33.986 1.000 28.207  0 73  PRO A C     1 ? ? 
ATOM   547  O O     . PRO A 1 92  ? 13.666  10.890 34.474 1.000 29.734  0 73  PRO A O     1 ? ? 
ATOM   548  C CB    . PRO A 1 92  ? 12.112  13.196 35.886 1.000 25.290  0 73  PRO A CB    1 ? ? 
ATOM   549  C CG    . PRO A 1 92  ? 10.770  12.951 36.546 1.000 25.379  0 73  PRO A CG    1 ? ? 
ATOM   550  C CD    . PRO A 1 92  ? 10.413  11.530 36.150 1.000 25.155  0 73  PRO A CD    1 ? ? 
ATOM   551  N N     . GLU A 1 93  ? 13.720  12.525 32.921 1.000 31.549  0 74  GLU A N     1 ? ? 
ATOM   552  C CA    . GLU A 1 93  ? 14.914  12.053 32.249 1.000 34.163  0 74  GLU A CA    1 ? ? 
ATOM   553  C C     . GLU A 1 93  ? 15.606  13.233 31.577 1.000 35.333  0 74  GLU A C     1 ? ? 
ATOM   554  O O     . GLU A 1 93  ? 14.961  14.244 31.269 1.000 38.751  0 74  GLU A O     1 ? ? 
ATOM   555  C CB    . GLU A 1 93  ? 14.542  10.984 31.234 1.000 36.197  0 74  GLU A CB    1 ? ? 
ATOM   556  C CG    . GLU A 1 93  ? 13.596  11.505 30.180 1.000 36.340  0 74  GLU A CG    1 ? ? 
ATOM   557  C CD    . GLU A 1 93  ? 13.135  10.538 29.121 1.000 41.430  0 74  GLU A CD    1 ? ? 
ATOM   558  O OE1   . GLU A 1 93  ? 13.632  10.688 28.003 1.000 41.628  0 74  GLU A OE1   1 ? ? 
ATOM   559  O OE2   . GLU A 1 93  ? 12.180  9.788  29.324 1.000 46.290  0 74  GLU A OE2   1 ? ? 
ATOM   560  N N     . GLY A 1 94  ? 16.922  13.087 31.374 1.000 31.651  0 75  GLY A N     1 ? ? 
ATOM   561  C CA    . GLY A 1 94  ? 17.699  14.061 30.625 1.000 27.196  0 75  GLY A CA    1 ? ? 
ATOM   562  C C     . GLY A 1 94  ? 17.663  15.441 31.271 1.000 24.281  0 75  GLY A C     1 ? ? 
ATOM   563  O O     . GLY A 1 94  ? 17.801  15.567 32.481 1.000 24.764  0 75  GLY A O     1 ? ? 
ATOM   564  N N     . ARG A 1 95  ? 17.512  16.472 30.437 1.000 23.142  0 76  ARG A N     1 ? ? 
ATOM   565  C CA    . ARG A 1 95  ? 17.442  17.853 30.886 1.000 24.336  0 76  ARG A CA    1 ? ? 
ATOM   566  C C     . ARG A 1 95  ? 16.027  18.152 31.392 1.000 22.848  0 76  ARG A C     1 ? ? 
ATOM   567  O O     . ARG A 1 95  ? 15.043  18.038 30.653 1.000 21.123  0 76  ARG A O     1 ? ? 
ATOM   568  C CB    . ARG A 1 95  ? 17.886  18.820 29.781 1.000 26.752  0 76  ARG A CB    1 ? ? 
ATOM   569  C CG    . ARG A 1 95  ? 17.923  20.277 30.224 1.000 30.318  0 76  ARG A CG    1 ? ? 
ATOM   570  C CD    . ARG A 1 95  ? 18.478  21.332 29.275 1.000 33.982  0 76  ARG A CD    1 ? ? 
ATOM   571  N NE    . ARG A 1 95  ? 18.757  22.562 29.998 1.000 38.682  0 76  ARG A NE    1 ? ? 
ATOM   572  C CZ    . ARG A 1 95  ? 18.139  23.727 29.859 1.000 39.584  0 76  ARG A CZ    1 ? ? 
ATOM   573  N NH1   . ARG A 1 95  ? 17.186  23.866 28.953 1.000 38.672  0 76  ARG A NH1   1 ? ? 
ATOM   574  N NH2   . ARG A 1 95  ? 18.505  24.733 30.661 1.000 36.631  0 76  ARG A NH2   1 ? ? 
ATOM   575  N N     . VAL A 1 96  ? 15.941  18.508 32.679 1.000 21.062  0 77  VAL A N     1 ? ? 
ATOM   576  C CA    . VAL A 1 96  ? 14.661  18.739 33.316 1.000 21.896  0 77  VAL A CA    1 ? ? 
ATOM   577  C C     . VAL A 1 96  ? 14.524  20.244 33.542 1.000 22.783  0 77  VAL A C     1 ? ? 
ATOM   578  O O     . VAL A 1 96  ? 15.411  20.852 34.138 1.000 23.780  0 77  VAL A O     1 ? ? 
ATOM   579  C CB    . VAL A 1 96  ? 14.560  17.944 34.635 1.000 21.771  0 77  VAL A CB    1 ? ? 
ATOM   580  C CG1   . VAL A 1 96  ? 13.282  18.243 35.391 1.000 21.381  0 77  VAL A CG1   1 ? ? 
ATOM   581  C CG2   . VAL A 1 96  ? 14.687  16.452 34.400 1.000 22.388  0 77  VAL A CG2   1 ? ? 
ATOM   582  N N     . ILE A 1 97  ? 13.424  20.824 33.048 1.000 21.362  0 78  ILE A N     1 ? ? 
ATOM   583  C CA    . ILE A 1 97  ? 13.052  22.188 33.378 1.000 21.142  0 78  ILE A CA    1 ? ? 
ATOM   584  C C     . ILE A 1 97  ? 11.932  22.165 34.414 1.000 20.179  0 78  ILE A C     1 ? ? 
ATOM   585  O O     . ILE A 1 97  ? 10.935  21.474 34.235 1.000 19.428  0 78  ILE A O     1 ? ? 
ATOM   586  C CB    . ILE A 1 97  ? 12.634  22.930 32.103 1.000 20.530  0 78  ILE A CB    1 ? ? 
ATOM   587  C CG1   . ILE A 1 97  ? 13.837  23.051 31.178 1.000 20.178  0 78  ILE A CG1   1 ? ? 
ATOM   588  C CG2   . ILE A 1 97  ? 12.049  24.297 32.430 1.000 21.475  0 78  ILE A CG2   1 ? ? 
ATOM   589  C CD1   . ILE A 1 97  ? 14.743  24.187 31.512 1.000 20.027  0 78  ILE A CD1   1 ? ? 
ATOM   590  N N     . ASP A 1 98  ? 12.102  22.970 35.466 1.000 19.593  0 79  ASP A N     1 ? ? 
ATOM   591  C CA    . ASP A 1 98  ? 11.129  23.082 36.536 1.000 19.098  0 79  ASP A CA    1 ? ? 
ATOM   592  C C     . ASP A 1 98  ? 10.604  24.516 36.594 1.000 18.732  0 79  ASP A C     1 ? ? 
ATOM   593  O O     . ASP A 1 98  ? 11.181  25.357 37.260 1.000 18.152  0 79  ASP A O     1 ? ? 
ATOM   594  C CB    . ASP A 1 98  ? 11.750  22.607 37.855 1.000 19.354  0 79  ASP A CB    1 ? ? 
ATOM   595  C CG    . ASP A 1 98  ? 10.789  22.690 39.029 1.000 19.177  0 79  ASP A CG    1 ? ? 
ATOM   596  O OD1   . ASP A 1 98  ? 9.597   22.885 38.777 1.000 19.575  0 79  ASP A OD1   1 ? ? 
ATOM   597  O OD2   . ASP A 1 98  ? 11.233  22.565 40.181 1.000 17.898  0 79  ASP A OD2   1 ? ? 
ATOM   598  N N     . LEU A 1 99  ? 9.473   24.782 35.929 1.000 19.446  0 80  LEU A N     1 ? ? 
ATOM   599  C CA    . LEU A 1 99  ? 8.909   26.126 35.872 1.000 18.281  0 80  LEU A CA    1 ? ? 
ATOM   600  C C     . LEU A 1 99  ? 8.095   26.404 37.133 1.000 17.878  0 80  LEU A C     1 ? ? 
ATOM   601  O O     . LEU A 1 99  ? 7.135   25.689 37.421 1.000 17.809  0 80  LEU A O     1 ? ? 
ATOM   602  C CB    . LEU A 1 99  ? 8.019   26.258 34.636 1.000 16.738  0 80  LEU A CB    1 ? ? 
ATOM   603  C CG    . LEU A 1 99  ? 8.693   26.040 33.285 1.000 17.315  0 80  LEU A CG    1 ? ? 
ATOM   604  C CD1   . LEU A 1 99  ? 7.694   26.260 32.150 1.000 17.831  0 80  LEU A CD1   1 ? ? 
ATOM   605  C CD2   . LEU A 1 99  ? 9.875   26.979 33.076 1.000 16.562  0 80  LEU A CD2   1 ? ? 
ATOM   606  N N     . GLY A 1 100 ? 8.462   27.479 37.838 1.000 16.957  0 81  GLY A N     1 ? ? 
ATOM   607  C CA    . GLY A 1 100 ? 7.837   27.791 39.110 1.000 16.983  0 81  GLY A CA    1 ? ? 
ATOM   608  C C     . GLY A 1 100 ? 8.394   26.922 40.233 1.000 16.861  0 81  GLY A C     1 ? ? 
ATOM   609  O O     . GLY A 1 100 ? 7.653   26.401 41.065 1.000 16.822  0 81  GLY A O     1 ? ? 
ATOM   610  N N     . CYS A 1 101 ? 9.722   26.795 40.258 1.000 16.754  0 82  CYS A N     1 ? ? 
ATOM   611  C CA    . CYS A 1 101 ? 10.393  25.882 41.161 1.000 16.704  0 82  CYS A CA    1 ? ? 
ATOM   612  C C     . CYS A 1 101 ? 10.266  26.309 42.615 1.000 16.121  0 82  CYS A C     1 ? ? 
ATOM   613  O O     . CYS A 1 101 ? 10.476  25.480 43.469 1.000 16.461  0 82  CYS A O     1 ? ? 
ATOM   614  C CB    . CYS A 1 101 ? 11.865  25.745 40.807 1.000 17.387  0 82  CYS A CB    1 ? ? 
ATOM   615  S SG    . CYS A 1 101 ? 12.840  27.244 41.111 1.000 18.781  0 82  CYS A SG    1 ? ? 
ATOM   616  N N     . GLY A 1 102 ? 9.978   27.581 42.895 1.000 15.862  0 83  GLY A N     1 ? ? 
ATOM   617  C CA    . GLY A 1 102 ? 9.867   28.032 44.273 1.000 16.291  0 83  GLY A CA    1 ? ? 
ATOM   618  C C     . GLY A 1 102 ? 11.101  27.613 45.064 1.000 17.046  0 83  GLY A C     1 ? ? 
ATOM   619  O O     . GLY A 1 102 ? 12.221  27.797 44.589 1.000 18.523  0 83  GLY A O     1 ? ? 
ATOM   620  N N     . ARG A 1 103 ? 10.893  26.982 46.223 1.000 17.256  0 84  ARG A N     1 ? ? 
ATOM   621  C CA    . ARG A 1 103 ? 11.999  26.619 47.095 1.000 17.900  0 84  ARG A CA    1 ? ? 
ATOM   622  C C     . ARG A 1 103 ? 12.862  25.532 46.472 1.000 17.822  0 84  ARG A C     1 ? ? 
ATOM   623  O O     . ARG A 1 103 ? 14.044  25.429 46.789 1.000 17.677  0 84  ARG A O     1 ? ? 
ATOM   624  C CB    . ARG A 1 103 ? 11.443  26.111 48.421 1.000 19.549  0 84  ARG A CB    1 ? ? 
ATOM   625  C CG    . ARG A 1 103 ? 10.909  27.213 49.308 1.000 21.097  0 84  ARG A CG    1 ? ? 
ATOM   626  C CD    . ARG A 1 103 ? 9.931   26.595 50.266 1.000 24.055  0 84  ARG A CD    1 ? ? 
ATOM   627  N NE    . ARG A 1 103 ? 10.716  26.000 51.317 1.000 27.032  0 84  ARG A NE    1 ? ? 
ATOM   628  C CZ    . ARG A 1 103 ? 10.954  26.549 52.482 1.000 29.673  0 84  ARG A CZ    1 ? ? 
ATOM   629  N NH1   . ARG A 1 103 ? 10.486  27.775 52.715 1.000 31.228  0 84  ARG A NH1   1 ? ? 
ATOM   630  N NH2   . ARG A 1 103 ? 11.688  25.845 53.348 1.000 29.616  0 84  ARG A NH2   1 ? ? 
ATOM   631  N N     . GLY A 1 104 ? 12.245  24.699 45.626 1.000 17.972  0 85  GLY A N     1 ? ? 
ATOM   632  C CA    . GLY A 1 104 ? 12.996  23.753 44.823 1.000 17.368  0 85  GLY A CA    1 ? ? 
ATOM   633  C C     . GLY A 1 104 ? 12.623  22.293 45.065 1.000 18.196  0 85  GLY A C     1 ? ? 
ATOM   634  O O     . GLY A 1 104 ? 13.414  21.424 44.711 1.000 19.555  0 85  GLY A O     1 ? ? 
ATOM   635  N N     . GLY A 1 105 ? 11.430  22.022 45.611 1.000 17.038  0 86  GLY A N     1 ? ? 
ATOM   636  C CA    . GLY A 1 105 ? 11.063  20.671 45.993 1.000 16.981  0 86  GLY A CA    1 ? ? 
ATOM   637  C C     . GLY A 1 105 ? 11.047  19.688 44.824 1.000 18.680  0 86  GLY A C     1 ? ? 
ATOM   638  O O     . GLY A 1 105 ? 11.487  18.544 44.959 1.000 18.449  0 86  GLY A O     1 ? ? 
ATOM   639  N N     . TRP A 1 106 ? 10.536  20.136 43.668 1.000 18.903  0 87  TRP A N     1 ? ? 
ATOM   640  C CA    . TRP A 1 106 ? 10.510  19.278 42.495 1.000 18.604  0 87  TRP A CA    1 ? ? 
ATOM   641  C C     . TRP A 1 106 ? 11.918  19.080 41.947 1.000 18.434  0 87  TRP A C     1 ? ? 
ATOM   642  O O     . TRP A 1 106 ? 12.278  17.969 41.564 1.000 19.165  0 87  TRP A O     1 ? ? 
ATOM   643  C CB    . TRP A 1 106 ? 9.603   19.858 41.415 1.000 18.149  0 87  TRP A CB    1 ? ? 
ATOM   644  C CG    . TRP A 1 106 ? 8.157   19.704 41.719 1.000 17.551  0 87  TRP A CG    1 ? ? 
ATOM   645  C CD1   . TRP A 1 106 ? 7.607   19.454 42.941 1.000 17.652  0 87  TRP A CD1   1 ? ? 
ATOM   646  C CD2   . TRP A 1 106 ? 7.065   19.791 40.787 1.000 16.555  0 87  TRP A CD2   1 ? ? 
ATOM   647  N NE1   . TRP A 1 106 ? 6.244   19.378 42.835 1.000 16.997  0 87  TRP A NE1   1 ? ? 
ATOM   648  C CE2   . TRP A 1 106 ? 5.882   19.594 41.531 1.000 16.487  0 87  TRP A CE2   1 ? ? 
ATOM   649  C CE3   . TRP A 1 106 ? 6.967   20.007 39.410 1.000 15.675  0 87  TRP A CE3   1 ? ? 
ATOM   650  C CZ2   . TRP A 1 106 ? 4.617   19.606 40.945 1.000 15.606  0 87  TRP A CZ2   1 ? ? 
ATOM   651  C CZ3   . TRP A 1 106 ? 5.716   20.055 38.832 1.000 15.557  0 87  TRP A CZ3   1 ? ? 
ATOM   652  C CH2   . TRP A 1 106 ? 4.563   19.848 39.591 1.000 15.971  0 87  TRP A CH2   1 ? ? 
ATOM   653  N N     . SER A 1 107 ? 12.703  20.161 41.912 1.000 16.975  0 88  SER A N     1 ? ? 
ATOM   654  C CA    . SER A 1 107 ? 14.039  20.117 41.340 1.000 16.721  0 88  SER A CA    1 ? ? 
ATOM   655  C C     . SER A 1 107 ? 14.935  19.157 42.111 1.000 15.950  0 88  SER A C     1 ? ? 
ATOM   656  O O     . SER A 1 107 ? 15.591  18.327 41.511 1.000 15.809  0 88  SER A O     1 ? ? 
ATOM   657  C CB    . SER A 1 107 ? 14.650  21.489 41.283 1.000 15.948  0 88  SER A CB    1 ? ? 
ATOM   658  O OG    . SER A 1 107 ? 14.102  22.239 40.222 1.000 17.329  0 88  SER A OG    1 ? ? 
ATOM   659  N N     . TYR A 1 108 ? 14.940  19.274 43.442 1.000 16.367  0 89  TYR A N     1 ? ? 
ATOM   660  C CA    . TYR A 1 108 ? 15.850  18.487 44.251 1.000 17.489  0 89  TYR A CA    1 ? ? 
ATOM   661  C C     . TYR A 1 108 ? 15.485  17.012 44.178 1.000 19.084  0 89  TYR A C     1 ? ? 
ATOM   662  O O     . TYR A 1 108 ? 16.366  16.150 44.156 1.000 20.415  0 89  TYR A O     1 ? ? 
ATOM   663  C CB    . TYR A 1 108 ? 15.856  18.995 45.687 1.000 17.597  0 89  TYR A CB    1 ? ? 
ATOM   664  C CG    . TYR A 1 108 ? 16.658  20.255 45.839 1.000 17.959  0 89  TYR A CG    1 ? ? 
ATOM   665  C CD1   . TYR A 1 108 ? 17.962  20.329 45.383 1.000 18.892  0 89  TYR A CD1   1 ? ? 
ATOM   666  C CD2   . TYR A 1 108 ? 16.122  21.379 46.432 1.000 18.325  0 89  TYR A CD2   1 ? ? 
ATOM   667  C CE1   . TYR A 1 108 ? 18.721  21.480 45.520 1.000 18.620  0 89  TYR A CE1   1 ? ? 
ATOM   668  C CE2   . TYR A 1 108 ? 16.862  22.535 46.585 1.000 18.171  0 89  TYR A CE2   1 ? ? 
ATOM   669  C CZ    . TYR A 1 108 ? 18.155  22.596 46.101 1.000 18.258  0 89  TYR A CZ    1 ? ? 
ATOM   670  O OH    . TYR A 1 108 ? 18.889  23.737 46.244 1.000 18.316  0 89  TYR A OH    1 ? ? 
ATOM   671  N N     . TYR A 1 109 ? 14.178  16.738 44.140 1.000 19.589  0 90  TYR A N     1 ? ? 
ATOM   672  C CA    . TYR A 1 109 ? 13.725  15.365 44.032 1.000 18.796  0 90  TYR A CA    1 ? ? 
ATOM   673  C C     . TYR A 1 109 ? 14.176  14.764 42.704 1.000 18.738  0 90  TYR A C     1 ? ? 
ATOM   674  O O     . TYR A 1 109 ? 14.660  13.638 42.699 1.000 18.772  0 90  TYR A O     1 ? ? 
ATOM   675  C CB    . TYR A 1 109 ? 12.211  15.286 44.187 1.000 19.703  0 90  TYR A CB    1 ? ? 
ATOM   676  C CG    . TYR A 1 109 ? 11.665  13.937 43.829 1.000 20.529  0 90  TYR A CG    1 ? ? 
ATOM   677  C CD1   . TYR A 1 109 ? 11.871  12.839 44.654 1.000 20.734  0 90  TYR A CD1   1 ? ? 
ATOM   678  C CD2   . TYR A 1 109 ? 10.973  13.757 42.647 1.000 20.208  0 90  TYR A CD2   1 ? ? 
ATOM   679  C CE1   . TYR A 1 109 ? 11.398  11.585 44.313 1.000 20.646  0 90  TYR A CE1   1 ? ? 
ATOM   680  C CE2   . TYR A 1 109 ? 10.498  12.509 42.290 1.000 20.942  0 90  TYR A CE2   1 ? ? 
ATOM   681  C CZ    . TYR A 1 109 ? 10.706  11.425 43.123 1.000 21.231  0 90  TYR A CZ    1 ? ? 
ATOM   682  O OH    . TYR A 1 109 ? 10.193  10.211 42.756 1.000 22.231  0 90  TYR A OH    1 ? ? 
ATOM   683  N N     . CYS A 1 110 ? 13.991  15.495 41.593 1.000 18.350  0 91  CYS A N     1 ? ? 
ATOM   684  C CA    . CYS A 1 110 ? 14.364  14.972 40.284 1.000 19.313  0 91  CYS A CA    1 ? ? 
ATOM   685  C C     . CYS A 1 110 ? 15.870  14.756 40.197 1.000 19.809  0 91  CYS A C     1 ? ? 
ATOM   686  O O     . CYS A 1 110 ? 16.345  13.942 39.412 1.000 20.387  0 91  CYS A O     1 ? ? 
ATOM   687  C CB    . CYS A 1 110 ? 13.952  15.898 39.148 1.000 19.325  0 91  CYS A CB    1 ? ? 
ATOM   688  S SG    . CYS A 1 110 ? 12.163  15.894 38.855 1.000 19.498  0 91  CYS A SG    1 ? ? 
ATOM   689  N N     . ALA A 1 111 ? 16.624  15.504 41.003 1.000 20.353  0 92  ALA A N     1 ? ? 
ATOM   690  C CA    . ALA A 1 111 ? 18.066  15.490 40.852 1.000 21.179  0 92  ALA A CA    1 ? ? 
ATOM   691  C C     . ALA A 1 111 ? 18.637  14.144 41.282 1.000 22.012  0 92  ALA A C     1 ? ? 
ATOM   692  O O     . ALA A 1 111 ? 19.753  13.814 40.906 1.000 23.105  0 92  ALA A O     1 ? ? 
ATOM   693  C CB    . ALA A 1 111 ? 18.680  16.625 41.620 1.000 22.116  0 92  ALA A CB    1 ? ? 
ATOM   694  N N     . GLY A 1 112 ? 17.883  13.363 42.063 1.000 22.655  0 93  GLY A N     1 ? ? 
ATOM   695  C CA    . GLY A 1 112 ? 18.356  12.078 42.556 1.000 21.476  0 93  GLY A CA    1 ? ? 
ATOM   696  C C     . GLY A 1 112 ? 17.858  10.896 41.728 1.000 21.619  0 93  GLY A C     1 ? ? 
ATOM   697  O O     . GLY A 1 112 ? 18.197  9.759  42.040 1.000 20.042  0 93  GLY A O     1 ? ? 
ATOM   698  N N     . LEU A 1 113 ? 17.112  11.173 40.648 1.000 22.163  0 94  LEU A N     1 ? ? 
ATOM   699  C CA    . LEU A 1 113 ? 16.612  10.123 39.770 1.000 25.218  0 94  LEU A CA    1 ? ? 
ATOM   700  C C     . LEU A 1 113 ? 17.636  9.722  38.713 1.000 26.775  0 94  LEU A C     1 ? ? 
ATOM   701  O O     . LEU A 1 113 ? 18.258  10.568 38.084 1.000 25.804  0 94  LEU A O     1 ? ? 
ATOM   702  C CB    . LEU A 1 113 ? 15.316  10.586 39.108 1.000 24.449  0 94  LEU A CB    1 ? ? 
ATOM   703  C CG    . LEU A 1 113 ? 14.213  10.961 40.093 1.000 23.988  0 94  LEU A CG    1 ? ? 
ATOM   704  C CD1   . LEU A 1 113 ? 12.987  11.443 39.354 1.000 25.055  0 94  LEU A CD1   1 ? ? 
ATOM   705  C CD2   . LEU A 1 113 ? 13.880  9.788  41.000 1.000 22.073  0 94  LEU A CD2   1 ? ? 
ATOM   706  N N     . LYS A 1 114 ? 17.732  8.415  38.475 1.000 30.199  0 95  LYS A N     1 ? ? 
ATOM   707  C CA    . LYS A 1 114 ? 18.751  7.814  37.638 1.000 33.806  0 95  LYS A CA    1 ? ? 
ATOM   708  C C     . LYS A 1 114 ? 18.822  8.458  36.255 1.000 33.161  0 95  LYS A C     1 ? ? 
ATOM   709  O O     . LYS A 1 114 ? 19.907  8.778  35.769 1.000 36.298  0 95  LYS A O     1 ? ? 
ATOM   710  C CB    . LYS A 1 114 ? 18.381  6.347  37.437 1.000 35.440  0 95  LYS A CB    1 ? ? 
ATOM   711  C CG    . LYS A 1 114 ? 19.289  5.341  38.096 1.000 37.300  0 95  LYS A CG    1 ? ? 
ATOM   712  C CD    . LYS A 1 114 ? 18.575  4.034  38.233 1.000 37.623  0 95  LYS A CD    1 ? ? 
ATOM   713  C CE    . LYS A 1 114 ? 17.382  4.094  39.168 1.000 41.041  0 95  LYS A CE    1 ? ? 
ATOM   714  N NZ    . LYS A 1 114 ? 16.293  3.182  38.736 1.000 40.962  0 95  LYS A NZ    1 ? ? 
ATOM   715  N N     . LYS A 1 115 ? 17.673  8.608  35.588 1.000 29.792  0 96  LYS A N     1 ? ? 
ATOM   716  C CA    . LYS A 1 115 ? 17.733  9.001  34.186 1.000 29.356  0 96  LYS A CA    1 ? ? 
ATOM   717  C C     . LYS A 1 115 ? 17.962  10.497 33.986 1.000 29.542  0 96  LYS A C     1 ? ? 
ATOM   718  O O     . LYS A 1 115 ? 18.089  10.947 32.847 1.000 27.776  0 96  LYS A O     1 ? ? 
ATOM   719  C CB    . LYS A 1 115 ? 16.480  8.558  33.437 1.000 28.184  0 96  LYS A CB    1 ? ? 
ATOM   720  C CG    . LYS A 1 115 ? 16.356  7.056  33.293 1.000 26.940  0 96  LYS A CG    1 ? ? 
ATOM   721  C CD    . LYS A 1 115 ? 15.442  6.695  32.206 1.000 29.306  0 96  LYS A CD    1 ? ? 
ATOM   722  C CE    . LYS A 1 115 ? 13.990  6.953  32.499 1.000 29.122  0 96  LYS A CE    1 ? ? 
ATOM   723  N NZ    . LYS A 1 115 ? 13.246  6.831  31.230 1.000 32.240  0 96  LYS A NZ    1 ? ? 
ATOM   724  N N     . VAL A 1 116 ? 17.982  11.263 35.081 1.000 28.848  0 97  VAL A N     1 ? ? 
ATOM   725  C CA    . VAL A 1 116 ? 18.044  12.713 35.002 1.000 29.404  0 97  VAL A CA    1 ? ? 
ATOM   726  C C     . VAL A 1 116 ? 19.504  13.142 34.956 1.000 28.549  0 97  VAL A C     1 ? ? 
ATOM   727  O O     . VAL A 1 116 ? 20.315  12.677 35.757 1.000 27.984  0 97  VAL A O     1 ? ? 
ATOM   728  C CB    . VAL A 1 116 ? 17.312  13.365 36.192 1.000 30.245  0 97  VAL A CB    1 ? ? 
ATOM   729  C CG1   . VAL A 1 116 ? 17.533  14.864 36.267 1.000 32.745  0 97  VAL A CG1   1 ? ? 
ATOM   730  C CG2   . VAL A 1 116 ? 15.838  13.049 36.184 1.000 28.482  0 97  VAL A CG2   1 ? ? 
ATOM   731  N N     . THR A 1 117 ? 19.792  14.072 34.038 1.000 28.452  0 98  THR A N     1 ? ? 
ATOM   732  C CA    . THR A 1 117 ? 21.150  14.517 33.793 1.000 29.103  0 98  THR A CA    1 ? ? 
ATOM   733  C C     . THR A 1 117 ? 21.358  15.969 34.231 1.000 29.654  0 98  THR A C     1 ? ? 
ATOM   734  O O     . THR A 1 117 ? 22.475  16.384 34.536 1.000 29.138  0 98  THR A O     1 ? ? 
ATOM   735  C CB    . THR A 1 117 ? 21.533  14.294 32.324 1.000 30.181  0 98  THR A CB    1 ? ? 
ATOM   736  O OG1   . THR A 1 117 ? 20.632  15.031 31.500 1.000 28.126  0 98  THR A OG1   1 ? ? 
ATOM   737  C CG2   . THR A 1 117 ? 21.582  12.826 31.950 1.000 29.337  0 98  THR A CG2   1 ? ? 
ATOM   738  N N     . GLU A 1 118 ? 20.286  16.757 34.241 1.000 29.958  0 99  GLU A N     1 ? ? 
ATOM   739  C CA    . GLU A 1 118 ? 20.385  18.182 34.509 1.000 31.602  0 99  GLU A CA    1 ? ? 
ATOM   740  C C     . GLU A 1 118 ? 19.023  18.700 34.951 1.000 30.926  0 99  GLU A C     1 ? ? 
ATOM   741  O O     . GLU A 1 118 ? 17.990  18.300 34.410 1.000 28.626  0 99  GLU A O     1 ? ? 
ATOM   742  C CB    . GLU A 1 118 ? 20.795  18.959 33.256 1.000 35.334  0 99  GLU A CB    1 ? ? 
ATOM   743  C CG    . GLU A 1 118 ? 21.130  20.393 33.576 1.000 38.856  0 99  GLU A CG    1 ? ? 
ATOM   744  C CD    . GLU A 1 118 ? 21.359  21.269 32.372 1.000 43.109  0 99  GLU A CD    1 ? ? 
ATOM   745  O OE1   . GLU A 1 118 ? 21.520  22.451 32.576 1.000 46.712  0 99  GLU A OE1   1 ? ? 
ATOM   746  O OE2   . GLU A 1 118 ? 21.390  20.754 31.267 1.000 42.878  0 99  GLU A OE2   1 ? ? 
ATOM   747  N N     . VAL A 1 119 ? 19.039  19.607 35.930 1.000 29.424  0 100 VAL A N     1 ? ? 
ATOM   748  C CA    . VAL A 1 119 ? 17.829  20.217 36.448 1.000 27.728  0 100 VAL A CA    1 ? ? 
ATOM   749  C C     . VAL A 1 119 ? 17.999  21.737 36.458 1.000 27.380  0 100 VAL A C     1 ? ? 
ATOM   750  O O     . VAL A 1 119 ? 18.895  22.278 37.113 1.000 27.203  0 100 VAL A O     1 ? ? 
ATOM   751  C CB    . VAL A 1 119 ? 17.484  19.688 37.860 1.000 26.941  0 100 VAL A CB    1 ? ? 
ATOM   752  C CG1   . VAL A 1 119 ? 16.144  20.242 38.317 1.000 26.148  0 100 VAL A CG1   1 ? ? 
ATOM   753  C CG2   . VAL A 1 119 ? 17.474  18.165 37.922 1.000 26.177  0 100 VAL A CG2   1 ? ? 
ATOM   754  N N     . ARG A 1 120 ? 17.106  22.421 35.745 1.000 25.912  0 101 ARG A N     1 ? ? 
ATOM   755  C CA    . ARG A 1 120 ? 17.108  23.870 35.709 1.000 23.786  0 101 ARG A CA    1 ? ? 
ATOM   756  C C     . ARG A 1 120 ? 15.755  24.366 36.215 1.000 21.364  0 101 ARG A C     1 ? ? 
ATOM   757  O O     . ARG A 1 120 ? 14.745  24.156 35.555 1.000 21.824  0 101 ARG A O     1 ? ? 
ATOM   758  C CB    . ARG A 1 120 ? 17.423  24.338 34.281 1.000 23.975  0 101 ARG A CB    1 ? ? 
ATOM   759  C CG    . ARG A 1 120 ? 17.172  25.811 34.069 1.000 25.794  0 101 ARG A CG    1 ? ? 
ATOM   760  C CD    . ARG A 1 120 ? 18.211  26.655 34.760 1.000 26.051  0 101 ARG A CD    1 ? ? 
ATOM   761  N NE    . ARG A 1 120 ? 18.951  27.348 33.717 1.000 26.954  0 101 ARG A NE    1 ? ? 
ATOM   762  C CZ    . ARG A 1 120 ? 20.015  26.838 33.130 1.000 26.443  0 101 ARG A CZ    1 ? ? 
ATOM   763  N NH1   . ARG A 1 120 ? 20.436  25.644 33.471 1.000 26.827  0 101 ARG A NH1   1 ? ? 
ATOM   764  N NH2   . ARG A 1 120 ? 20.672  27.507 32.222 1.000 28.340  0 101 ARG A NH2   1 ? ? 
ATOM   765  N N     . GLY A 1 121 ? 15.756  25.009 37.389 1.000 19.009  0 102 GLY A N     1 ? ? 
ATOM   766  C CA    . GLY A 1 121 ? 14.557  25.574 37.977 1.000 17.544  0 102 GLY A CA    1 ? ? 
ATOM   767  C C     . GLY A 1 121 ? 14.483  27.096 37.855 1.000 18.146  0 102 GLY A C     1 ? ? 
ATOM   768  O O     . GLY A 1 121 ? 15.503  27.775 37.979 1.000 17.608  0 102 GLY A O     1 ? ? 
ATOM   769  N N     . TYR A 1 122 ? 13.257  27.605 37.634 1.000 17.492  0 103 TYR A N     1 ? ? 
ATOM   770  C CA    . TYR A 1 122 ? 12.986  29.020 37.432 1.000 17.568  0 103 TYR A CA    1 ? ? 
ATOM   771  C C     . TYR A 1 122 ? 11.836  29.445 38.322 1.000 17.479  0 103 TYR A C     1 ? ? 
ATOM   772  O O     . TYR A 1 122 ? 10.782  28.824 38.315 1.000 17.804  0 103 TYR A O     1 ? ? 
ATOM   773  C CB    . TYR A 1 122 ? 12.542  29.326 35.999 1.000 18.341  0 103 TYR A CB    1 ? ? 
ATOM   774  C CG    . TYR A 1 122 ? 13.613  29.138 34.969 1.000 19.248  0 103 TYR A CG    1 ? ? 
ATOM   775  C CD1   . TYR A 1 122 ? 14.748  29.925 34.980 1.000 18.710  0 103 TYR A CD1   1 ? ? 
ATOM   776  C CD2   . TYR A 1 122 ? 13.467  28.191 33.970 1.000 19.546  0 103 TYR A CD2   1 ? ? 
ATOM   777  C CE1   . TYR A 1 122 ? 15.734  29.748 34.032 1.000 18.844  0 103 TYR A CE1   1 ? ? 
ATOM   778  C CE2   . TYR A 1 122 ? 14.441  28.013 33.010 1.000 19.193  0 103 TYR A CE2   1 ? ? 
ATOM   779  C CZ    . TYR A 1 122 ? 15.563  28.809 33.032 1.000 18.989  0 103 TYR A CZ    1 ? ? 
ATOM   780  O OH    . TYR A 1 122 ? 16.511  28.619 32.078 1.000 20.394  0 103 TYR A OH    1 ? ? 
ATOM   781  N N     . THR A 1 123 ? 12.016  30.540 39.048 1.000 17.741  0 104 THR A N     1 ? ? 
ATOM   782  C CA    . THR A 1 123 ? 10.912  31.011 39.856 1.000 18.237  0 104 THR A CA    1 ? ? 
ATOM   783  C C     . THR A 1 123 ? 11.014  32.523 39.990 1.000 18.327  0 104 THR A C     1 ? ? 
ATOM   784  O O     . THR A 1 123 ? 12.083  33.094 39.819 1.000 18.058  0 104 THR A O     1 ? ? 
ATOM   785  C CB    . THR A 1 123 ? 10.885  30.264 41.191 1.000 18.017  0 104 THR A CB    1 ? ? 
ATOM   786  O OG1   . THR A 1 123 ? 9.610   30.397 41.817 1.000 18.307  0 104 THR A OG1   1 ? ? 
ATOM   787  C CG2   . THR A 1 123 ? 11.991  30.703 42.114 1.000 17.799  0 104 THR A CG2   1 ? ? 
ATOM   788  N N     . LYS A 1 124 ? 9.888   33.147 40.329 1.000 19.668  0 105 LYS A N     1 ? ? 
ATOM   789  C CA    . LYS A 1 124 ? 9.768   34.590 40.311 1.000 20.742  0 105 LYS A CA    1 ? ? 
ATOM   790  C C     . LYS A 1 124 ? 10.522  35.218 41.479 1.000 20.564  0 105 LYS A C     1 ? ? 
ATOM   791  O O     . LYS A 1 124 ? 11.209  36.214 41.313 1.000 20.599  0 105 LYS A O     1 ? ? 
ATOM   792  C CB    . LYS A 1 124 ? 8.283   34.931 40.387 1.000 21.090  0 105 LYS A CB    1 ? ? 
ATOM   793  C CG    . LYS A 1 124 ? 7.946   36.280 39.792 1.000 23.070  0 105 LYS A CG    1 ? ? 
ATOM   794  C CD    . LYS A 1 124 ? 6.485   36.625 39.996 1.000 22.750  0 105 LYS A CD    1 ? ? 
ATOM   795  C CE    . LYS A 1 124 ? 6.266   38.045 40.507 1.000 22.920  0 105 LYS A CE    1 ? ? 
ATOM   796  N NZ    . LYS A 1 124 ? 6.940   39.112 39.716 1.000 23.017  0 105 LYS A NZ    1 ? ? 
ATOM   797  N N     . GLY A 1 125 ? 10.375  34.642 42.666 1.000 20.670  0 106 GLY A N     1 ? ? 
ATOM   798  C CA    . GLY A 1 125 ? 10.973  35.241 43.847 1.000 19.198  0 106 GLY A CA    1 ? ? 
ATOM   799  C C     . GLY A 1 125 ? 10.408  36.620 44.161 1.000 18.192  0 106 GLY A C     1 ? ? 
ATOM   800  O O     . GLY A 1 125 ? 9.460   37.089 43.544 1.000 16.769  0 106 GLY A O     1 ? ? 
ATOM   801  N N     . GLY A 1 126 ? 11.058  37.264 45.136 1.000 19.212  0 107 GLY A N     1 ? ? 
ATOM   802  C CA    . GLY A 1 126 ? 10.738  38.616 45.555 1.000 20.523  0 107 GLY A CA    1 ? ? 
ATOM   803  C C     . GLY A 1 126 ? 9.527   38.639 46.481 1.000 20.993  0 107 GLY A C     1 ? ? 
ATOM   804  O O     . GLY A 1 126 ? 9.066   37.607 46.958 1.000 20.574  0 107 GLY A O     1 ? ? 
ATOM   805  N N     . PRO A 1 127 ? 8.976   39.836 46.752 1.000 22.657  0 108 PRO A N     1 ? ? 
ATOM   806  C CA    . PRO A 1 127 ? 7.807   39.960 47.622 1.000 23.420  0 108 PRO A CA    1 ? ? 
ATOM   807  C C     . PRO A 1 127 ? 6.664   39.057 47.170 1.000 23.665  0 108 PRO A C     1 ? ? 
ATOM   808  O O     . PRO A 1 127 ? 6.239   39.100 46.008 1.000 24.099  0 108 PRO A O     1 ? ? 
ATOM   809  C CB    . PRO A 1 127 ? 7.433   41.446 47.461 1.000 23.881  0 108 PRO A CB    1 ? ? 
ATOM   810  C CG    . PRO A 1 127 ? 8.768   42.115 47.169 1.000 22.806  0 108 PRO A CG    1 ? ? 
ATOM   811  C CD    . PRO A 1 127 ? 9.465   41.135 46.252 1.000 22.572  0 108 PRO A CD    1 ? ? 
ATOM   812  N N     . GLY A 1 128 ? 6.178   38.243 48.113 1.000 23.360  0 109 GLY A N     1 ? ? 
ATOM   813  C CA    . GLY A 1 128 ? 5.000   37.429 47.869 1.000 22.557  0 109 GLY A CA    1 ? ? 
ATOM   814  C C     . GLY A 1 128 ? 5.325   36.044 47.311 1.000 23.172  0 109 GLY A C     1 ? ? 
ATOM   815  O O     . GLY A 1 128 ? 4.425   35.224 47.146 1.000 23.622  0 109 GLY A O     1 ? ? 
ATOM   816  N N     . HIS A 1 129 ? 6.593   35.765 47.018 1.000 22.149  0 110 HIS A N     1 ? ? 
ATOM   817  C CA    . HIS A 1 129 ? 6.892   34.513 46.348 1.000 23.046  0 110 HIS A CA    1 ? ? 
ATOM   818  C C     . HIS A 1 129 ? 8.078   33.846 47.023 1.000 23.319  0 110 HIS A C     1 ? ? 
ATOM   819  O O     . HIS A 1 129 ? 9.011   34.517 47.451 1.000 24.650  0 110 HIS A O     1 ? ? 
ATOM   820  C CB    . HIS A 1 129 ? 7.182   34.754 44.866 1.000 22.492  0 110 HIS A CB    1 ? ? 
ATOM   821  C CG    . HIS A 1 129 ? 6.062   35.405 44.126 1.000 22.970  0 110 HIS A CG    1 ? ? 
ATOM   822  N ND1   . HIS A 1 129 ? 5.164   34.685 43.368 1.000 23.072  0 110 HIS A ND1   1 ? ? 
ATOM   823  C CD2   . HIS A 1 129 ? 5.690   36.697 44.005 1.000 22.495  0 110 HIS A CD2   1 ? ? 
ATOM   824  C CE1   . HIS A 1 129 ? 4.302   35.498 42.795 1.000 22.606  0 110 HIS A CE1   1 ? ? 
ATOM   825  N NE2   . HIS A 1 129 ? 4.607   36.742 43.165 1.000 22.730  0 110 HIS A NE2   1 ? ? 
ATOM   826  N N     . GLU A 1 130 ? 8.063   32.513 47.051 1.000 24.037  0 111 GLU A N     1 ? ? 
ATOM   827  C CA    . GLU A 1 130 ? 9.131   31.741 47.672 1.000 24.751  0 111 GLU A CA    1 ? ? 
ATOM   828  C C     . GLU A 1 130 ? 10.428  31.839 46.873 1.000 23.365  0 111 GLU A C     1 ? ? 
ATOM   829  O O     . GLU A 1 130 ? 10.419  31.835 45.646 1.000 23.620  0 111 GLU A O     1 ? ? 
ATOM   830  C CB    . GLU A 1 130 ? 8.689   30.299 47.883 1.000 27.024  0 111 GLU A CB    1 ? ? 
ATOM   831  C CG    . GLU A 1 130 ? 7.659   30.181 49.004 1.000 31.857  0 111 GLU A CG    1 ? ? 
ATOM   832  C CD    . GLU A 1 130 ? 8.134   30.284 50.462 1.000 34.713  0 111 GLU A CD    1 ? ? 
ATOM   833  O OE1   . GLU A 1 130 ? 9.285   30.713 50.734 1.000 36.455  0 111 GLU A OE1   1 ? ? 
ATOM   834  O OE2   . GLU A 1 130 ? 7.354   29.904 51.340 1.000 36.066  0 111 GLU A OE2   1 ? ? 
ATOM   835  N N     . GLU A 1 131 ? 11.543  31.920 47.600 1.000 22.328  0 112 GLU A N     1 ? ? 
ATOM   836  C CA    . GLU A 1 131 ? 12.875  31.962 47.017 1.000 21.874  0 112 GLU A CA    1 ? ? 
ATOM   837  C C     . GLU A 1 131 ? 13.507  30.574 47.051 1.000 20.547  0 112 GLU A C     1 ? ? 
ATOM   838  O O     . GLU A 1 131 ? 13.292  29.817 47.997 1.000 19.687  0 112 GLU A O     1 ? ? 
ATOM   839  C CB    . GLU A 1 131 ? 13.773  32.866 47.857 1.000 23.050  0 112 GLU A CB    1 ? ? 
ATOM   840  C CG    . GLU A 1 131 ? 13.377  34.323 47.788 1.000 25.233  0 112 GLU A CG    1 ? ? 
ATOM   841  C CD    . GLU A 1 131 ? 13.742  34.988 46.470 1.000 27.909  0 112 GLU A CD    1 ? ? 
ATOM   842  O OE1   . GLU A 1 131 ? 14.495  34.372 45.670 1.000 27.239  0 112 GLU A OE1   1 ? ? 
ATOM   843  O OE2   . GLU A 1 131 ? 13.252  36.120 46.224 1.000 30.095  0 112 GLU A OE2   1 ? ? 
ATOM   844  N N     . PRO A 1 132 ? 14.316  30.196 46.035 1.000 19.504  0 113 PRO A N     1 ? ? 
ATOM   845  C CA    . PRO A 1 132 ? 15.014  28.914 46.050 1.000 19.465  0 113 PRO A CA    1 ? ? 
ATOM   846  C C     . PRO A 1 132 ? 15.849  28.746 47.309 1.000 18.969  0 113 PRO A C     1 ? ? 
ATOM   847  O O     . PRO A 1 132 ? 16.441  29.700 47.797 1.000 18.434  0 113 PRO A O     1 ? ? 
ATOM   848  C CB    . PRO A 1 132 ? 15.905  28.969 44.808 1.000 19.356  0 113 PRO A CB    1 ? ? 
ATOM   849  C CG    . PRO A 1 132 ? 15.131  29.867 43.877 1.000 19.689  0 113 PRO A CG    1 ? ? 
ATOM   850  C CD    . PRO A 1 132 ? 14.522  30.918 44.776 1.000 19.738  0 113 PRO A CD    1 ? ? 
ATOM   851  N N     . VAL A 1 133 ? 15.844  27.522 47.828 1.000 18.989  0 114 VAL A N     1 ? ? 
ATOM   852  C CA    . VAL A 1 133 ? 16.569  27.173 49.029 1.000 19.496  0 114 VAL A CA    1 ? ? 
ATOM   853  C C     . VAL A 1 133 ? 17.760  26.308 48.605 1.000 21.056  0 114 VAL A C     1 ? ? 
ATOM   854  O O     . VAL A 1 133 ? 17.589  25.287 47.941 1.000 22.725  0 114 VAL A O     1 ? ? 
ATOM   855  C CB    . VAL A 1 133 ? 15.642  26.469 50.039 1.000 18.331  0 114 VAL A CB    1 ? ? 
ATOM   856  C CG1   . VAL A 1 133 ? 16.435  25.873 51.189 1.000 18.795  0 114 VAL A CG1   1 ? ? 
ATOM   857  C CG2   . VAL A 1 133 ? 14.560  27.399 50.552 1.000 17.800  0 114 VAL A CG2   1 ? ? 
ATOM   858  N N     . PRO A 1 134 ? 19.015  26.710 48.901 1.000 21.799  0 115 PRO A N     1 ? ? 
ATOM   859  C CA    . PRO A 1 134 ? 20.176  25.911 48.497 1.000 22.150  0 115 PRO A CA    1 ? ? 
ATOM   860  C C     . PRO A 1 134 ? 20.288  24.654 49.357 1.000 23.503  0 115 PRO A C     1 ? ? 
ATOM   861  O O     . PRO A 1 134 ? 20.142  24.735 50.579 1.000 25.270  0 115 PRO A O     1 ? ? 
ATOM   862  C CB    . PRO A 1 134 ? 21.356  26.864 48.742 1.000 21.582  0 115 PRO A CB    1 ? ? 
ATOM   863  C CG    . PRO A 1 134 ? 20.866  27.843 49.803 1.000 21.704  0 115 PRO A CG    1 ? ? 
ATOM   864  C CD    . PRO A 1 134 ? 19.373  27.951 49.611 1.000 21.081  0 115 PRO A CD    1 ? ? 
ATOM   865  N N     . MET A 1 135 ? 20.514  23.501 48.709 1.000 24.822  0 116 MET A N     1 ? ? 
ATOM   866  C CA    . MET A 1 135 ? 20.589  22.224 49.412 1.000 24.423  0 116 MET A CA    1 ? ? 
ATOM   867  C C     . MET A 1 135 ? 21.728  21.362 48.854 1.000 24.979  0 116 MET A C     1 ? ? 
ATOM   868  O O     . MET A 1 135 ? 22.251  21.630 47.769 1.000 24.516  0 116 MET A O     1 ? ? 
ATOM   869  C CB    . MET A 1 135 ? 19.264  21.453 49.330 1.000 22.540  0 116 MET A CB    1 ? ? 
ATOM   870  C CG    . MET A 1 135 ? 18.117  22.151 50.019 1.000 22.692  0 116 MET A CG    1 ? ? 
ATOM   871  S SD    . MET A 1 135 ? 18.311  22.263 51.845 1.000 23.959  0 116 MET A SD    1 ? ? 
ATOM   872  C CE    . MET A 1 135 ? 17.955  20.575 52.334 1.000 24.250  0 116 MET A CE    1 ? ? 
ATOM   873  N N     . SER A 1 136 ? 22.118  20.339 49.634 1.000 23.139  0 117 SER A N     1 ? ? 
ATOM   874  C CA    . SER A 1 136 ? 23.114  19.368 49.213 1.000 24.187  0 117 SER A CA    1 ? ? 
ATOM   875  C C     . SER A 1 136 ? 22.549  17.957 49.297 1.000 24.487  0 117 SER A C     1 ? ? 
ATOM   876  O O     . SER A 1 136 ? 23.263  17.013 49.635 1.000 24.980  0 117 SER A O     1 ? ? 
ATOM   877  C CB    . SER A 1 136 ? 24.392  19.412 50.008 1.000 24.373  0 117 SER A CB    1 ? ? 
ATOM   878  O OG    . SER A 1 136 ? 24.632  20.658 50.594 1.000 24.597  0 117 SER A OG    1 ? ? 
ATOM   879  N N     . THR A 1 137 ? 21.259  17.827 49.014 1.000 24.900  0 118 THR A N     1 ? ? 
ATOM   880  C CA    . THR A 1 137 ? 20.637  16.523 48.876 1.000 24.672  0 118 THR A CA    1 ? ? 
ATOM   881  C C     . THR A 1 137 ? 21.204  15.819 47.647 1.000 25.611  0 118 THR A C     1 ? ? 
ATOM   882  O O     . THR A 1 137 ? 21.824  16.456 46.799 1.000 24.661  0 118 THR A O     1 ? ? 
ATOM   883  C CB    . THR A 1 137 ? 19.119  16.684 48.836 1.000 23.502  0 118 THR A CB    1 ? ? 
ATOM   884  O OG1   . THR A 1 137 ? 18.860  17.738 47.913 1.000 22.935  0 118 THR A OG1   1 ? ? 
ATOM   885  C CG2   . THR A 1 137 ? 18.574  17.068 50.190 1.000 22.780  0 118 THR A CG2   1 ? ? 
ATOM   886  N N     . TYR A 1 138 ? 20.982  14.504 47.558 1.000 28.473  0 119 TYR A N     1 ? ? 
ATOM   887  C CA    . TYR A 1 138 ? 21.641  13.700 46.544 1.000 29.574  0 119 TYR A CA    1 ? ? 
ATOM   888  C C     . TYR A 1 138 ? 21.391  14.250 45.139 1.000 29.604  0 119 TYR A C     1 ? ? 
ATOM   889  O O     . TYR A 1 138 ? 20.245  14.412 44.712 1.000 28.338  0 119 TYR A O     1 ? ? 
ATOM   890  C CB    . TYR A 1 138 ? 21.229  12.234 46.661 1.000 32.764  0 119 TYR A CB    1 ? ? 
ATOM   891  C CG    . TYR A 1 138 ? 21.898  11.350 45.639 1.000 34.596  0 119 TYR A CG    1 ? ? 
ATOM   892  C CD1   . TYR A 1 138 ? 23.266  11.137 45.678 1.000 34.235  0 119 TYR A CD1   1 ? ? 
ATOM   893  C CD2   . TYR A 1 138 ? 21.165  10.735 44.635 1.000 35.174  0 119 TYR A CD2   1 ? ? 
ATOM   894  C CE1   . TYR A 1 138 ? 23.888  10.329 44.741 1.000 37.796  0 119 TYR A CE1   1 ? ? 
ATOM   895  C CE2   . TYR A 1 138 ? 21.780  9.953  43.671 1.000 38.246  0 119 TYR A CE2   1 ? ? 
ATOM   896  C CZ    . TYR A 1 138 ? 23.144  9.731  43.739 1.000 38.740  0 119 TYR A CZ    1 ? ? 
ATOM   897  O OH    . TYR A 1 138 ? 23.758  8.952  42.805 1.000 38.558  0 119 TYR A OH    1 ? ? 
ATOM   898  N N     . GLY A 1 139 ? 22.489  14.524 44.430 1.000 29.197  0 120 GLY A N     1 ? ? 
ATOM   899  C CA    . GLY A 1 139 ? 22.403  14.982 43.053 1.000 29.412  0 120 GLY A CA    1 ? ? 
ATOM   900  C C     . GLY A 1 139 ? 22.323  16.501 42.943 1.000 30.255  0 120 GLY A C     1 ? ? 
ATOM   901  O O     . GLY A 1 139 ? 22.048  16.996 41.858 1.000 31.500  0 120 GLY A O     1 ? ? 
ATOM   902  N N     . TRP A 1 140 ? 22.567  17.232 44.042 1.000 29.498  0 121 TRP A N     1 ? ? 
ATOM   903  C CA    . TRP A 1 140 ? 22.450  18.684 44.049 1.000 28.949  0 121 TRP A CA    1 ? ? 
ATOM   904  C C     . TRP A 1 140 ? 23.332  19.308 42.969 1.000 28.591  0 121 TRP A C     1 ? ? 
ATOM   905  O O     . TRP A 1 140 ? 22.994  20.360 42.425 1.000 29.952  0 121 TRP A O     1 ? ? 
ATOM   906  C CB    . TRP A 1 140 ? 22.763  19.261 45.433 1.000 26.773  0 121 TRP A CB    1 ? ? 
ATOM   907  C CG    . TRP A 1 140 ? 24.181  19.020 45.824 1.000 28.993  0 121 TRP A CG    1 ? ? 
ATOM   908  C CD1   . TRP A 1 140 ? 24.675  17.935 46.479 1.000 30.293  0 121 TRP A CD1   1 ? ? 
ATOM   909  C CD2   . TRP A 1 140 ? 25.312  19.853 45.526 1.000 29.452  0 121 TRP A CD2   1 ? ? 
ATOM   910  N NE1   . TRP A 1 140 ? 26.020  18.061 46.665 1.000 31.449  0 121 TRP A NE1   1 ? ? 
ATOM   911  C CE2   . TRP A 1 140 ? 26.444  19.209 46.063 1.000 29.889  0 121 TRP A CE2   1 ? ? 
ATOM   912  C CE3   . TRP A 1 140 ? 25.483  21.084 44.876 1.000 29.736  0 121 TRP A CE3   1 ? ? 
ATOM   913  C CZ2   . TRP A 1 140 ? 27.722  19.749 45.973 1.000 29.679  0 121 TRP A CZ2   1 ? ? 
ATOM   914  C CZ3   . TRP A 1 140 ? 26.749  21.616 44.774 1.000 28.591  0 121 TRP A CZ3   1 ? ? 
ATOM   915  C CH2   . TRP A 1 140 ? 27.846  20.961 45.332 1.000 29.957  0 121 TRP A CH2   1 ? ? 
ATOM   916  N N     . ASN A 1 141 ? 24.442  18.648 42.641 1.000 28.091  0 122 ASN A N     1 ? ? 
ATOM   917  C CA    . ASN A 1 141 ? 25.424  19.241 41.749 1.000 27.957  0 122 ASN A CA    1 ? ? 
ATOM   918  C C     . ASN A 1 141 ? 24.926  19.359 40.308 1.000 28.543  0 122 ASN A C     1 ? ? 
ATOM   919  O O     . ASN A 1 141 ? 25.598  19.965 39.484 1.000 27.924  0 122 ASN A O     1 ? ? 
ATOM   920  C CB    . ASN A 1 141 ? 26.701  18.415 41.742 1.000 28.682  0 122 ASN A CB    1 ? ? 
ATOM   921  C CG    . ASN A 1 141 ? 26.426  16.969 41.401 1.000 29.858  0 122 ASN A CG    1 ? ? 
ATOM   922  O OD1   . ASN A 1 141 ? 25.794  16.262 42.183 1.000 29.712  0 122 ASN A OD1   1 ? ? 
ATOM   923  N ND2   . ASN A 1 141 ? 26.860  16.556 40.221 1.000 29.852  0 122 ASN A ND2   1 ? ? 
ATOM   924  N N     . ILE A 1 142 ? 23.775  18.763 39.980 1.000 29.988  0 123 ILE A N     1 ? ? 
ATOM   925  C CA    . ILE A 1 142 ? 23.240  18.893 38.629 1.000 31.396  0 123 ILE A CA    1 ? ? 
ATOM   926  C C     . ILE A 1 142 ? 22.067  19.867 38.603 1.000 32.687  0 123 ILE A C     1 ? ? 
ATOM   927  O O     . ILE A 1 142 ? 21.440  19.974 37.558 1.000 33.163  0 123 ILE A O     1 ? ? 
ATOM   928  C CB    . ILE A 1 142 ? 22.886  17.519 38.013 1.000 32.475  0 123 ILE A CB    1 ? ? 
ATOM   929  C CG1   . ILE A 1 142 ? 21.622  16.914 38.641 1.000 34.558  0 123 ILE A CG1   1 ? ? 
ATOM   930  C CG2   . ILE A 1 142 ? 24.090  16.580 38.111 1.000 28.920  0 123 ILE A CG2   1 ? ? 
ATOM   931  C CD1   . ILE A 1 142 ? 21.023  15.788 37.824 1.000 32.960  0 123 ILE A CD1   1 ? ? 
ATOM   932  N N     . VAL A 1 143 ? 21.806  20.578 39.717 1.000 33.015  0 124 VAL A N     1 ? ? 
ATOM   933  C CA    . VAL A 1 143 ? 20.679  21.497 39.862 1.000 33.072  0 124 VAL A CA    1 ? ? 
ATOM   934  C C     . VAL A 1 143 ? 21.166  22.938 39.733 1.000 33.338  0 124 VAL A C     1 ? ? 
ATOM   935  O O     . VAL A 1 143 ? 22.188  23.280 40.307 1.000 38.203  0 124 VAL A O     1 ? ? 
ATOM   936  C CB    . VAL A 1 143 ? 19.971  21.293 41.219 1.000 32.847  0 124 VAL A CB    1 ? ? 
ATOM   937  C CG1   . VAL A 1 143 ? 18.808  22.251 41.430 1.000 32.751  0 124 VAL A CG1   1 ? ? 
ATOM   938  C CG2   . VAL A 1 143 ? 19.480  19.864 41.368 1.000 34.743  0 124 VAL A CG2   1 ? ? 
ATOM   939  N N     . LYS A 1 144 ? 20.417  23.771 38.997 1.000 32.764  0 125 LYS A N     1 ? ? 
ATOM   940  C CA    . LYS A 1 144 ? 20.583  25.217 39.039 1.000 30.398  0 125 LYS A CA    1 ? ? 
ATOM   941  C C     . LYS A 1 144 ? 19.208  25.856 39.184 1.000 28.733  0 125 LYS A C     1 ? ? 
ATOM   942  O O     . LYS A 1 144 ? 18.371  25.720 38.297 1.000 29.554  0 125 LYS A O     1 ? ? 
ATOM   943  C CB    . LYS A 1 144 ? 21.268  25.734 37.770 1.000 31.911  0 125 LYS A CB    1 ? ? 
ATOM   944  C CG    . LYS A 1 144 ? 21.552  27.226 37.798 1.000 32.552  0 125 LYS A CG    1 ? ? 
ATOM   945  C CD    . LYS A 1 144 ? 22.033  27.802 36.493 1.000 33.839  0 125 LYS A CD    1 ? ? 
ATOM   946  C CE    . LYS A 1 144 ? 22.517  29.223 36.718 1.000 35.014  0 125 LYS A CE    1 ? ? 
ATOM   947  N NZ    . LYS A 1 144 ? 23.334  29.718 35.595 1.000 38.045  0 125 LYS A NZ    1 ? ? 
ATOM   948  N N     . LEU A 1 145 ? 18.982  26.549 40.307 1.000 26.290  0 126 LEU A N     1 ? ? 
ATOM   949  C CA    . LEU A 1 145 ? 17.721  27.232 40.566 1.000 24.359  0 126 LEU A CA    1 ? ? 
ATOM   950  C C     . LEU A 1 145 ? 17.922  28.733 40.424 1.000 24.620  0 126 LEU A C     1 ? ? 
ATOM   951  O O     . LEU A 1 145 ? 18.791  29.305 41.069 1.000 26.787  0 126 LEU A O     1 ? ? 
ATOM   952  C CB    . LEU A 1 145 ? 17.258  26.926 41.994 1.000 22.431  0 126 LEU A CB    1 ? ? 
ATOM   953  C CG    . LEU A 1 145 ? 17.028  25.464 42.344 1.000 21.305  0 126 LEU A CG    1 ? ? 
ATOM   954  C CD1   . LEU A 1 145 ? 16.515  25.383 43.759 1.000 19.651  0 126 LEU A CD1   1 ? ? 
ATOM   955  C CD2   . LEU A 1 145 ? 16.045  24.837 41.364 1.000 21.564  0 126 LEU A CD2   1 ? ? 
ATOM   956  N N     . MET A 1 146 ? 17.080  29.372 39.611 1.000 26.128  0 127 MET A N     1 ? ? 
ATOM   957  C CA    . MET A 1 146 ? 17.239  30.771 39.251 1.000 26.336  0 127 MET A CA    1 ? ? 
ATOM   958  C C     . MET A 1 146 ? 16.003  31.562 39.667 1.000 26.005  0 127 MET A C     1 ? ? 
ATOM   959  O O     . MET A 1 146 ? 14.893  31.307 39.217 1.000 25.521  0 127 MET A O     1 ? ? 
ATOM   960  C CB    . MET A 1 146 ? 17.462  30.912 37.740 1.000 28.322  0 127 MET A CB    1 ? ? 
ATOM   961  C CG    . MET A 1 146 ? 18.653  30.100 37.236 1.000 32.501  0 127 MET A CG    1 ? ? 
ATOM   962  S SD    . MET A 1 146 ? 19.501  30.927 35.929 1.000 39.994  0 127 MET A SD    1 ? ? 
ATOM   963  C CE    . MET A 1 146 ? 18.784  30.295 34.428 1.000 37.740  0 127 MET A CE    1 ? ? 
ATOM   964  N N     . SER A 1 147 ? 16.214  32.537 40.554 1.000 25.223  0 128 SER A N     1 ? ? 
ATOM   965  C CA    . SER A 1 147 ? 15.146  33.396 41.035 1.000 24.044  0 128 SER A CA    1 ? ? 
ATOM   966  C C     . SER A 1 147 ? 15.030  34.593 40.100 1.000 25.891  0 128 SER A C     1 ? ? 
ATOM   967  O O     . SER A 1 147 ? 15.798  34.681 39.143 1.000 29.228  0 128 SER A O     1 ? ? 
ATOM   968  C CB    . SER A 1 147 ? 15.416  33.788 42.450 1.000 21.405  0 128 SER A CB    1 ? ? 
ATOM   969  O OG    . SER A 1 147 ? 14.234  34.216 43.084 1.000 21.789  0 128 SER A OG    1 ? ? 
ATOM   970  N N     . GLY A 1 148 ? 14.022  35.451 40.330 1.000 25.054  0 129 GLY A N     1 ? ? 
ATOM   971  C CA    . GLY A 1 148 ? 13.823  36.670 39.556 1.000 25.582  0 129 GLY A CA    1 ? ? 
ATOM   972  C C     . GLY A 1 148 ? 13.473  36.389 38.095 1.000 26.825  0 129 GLY A C     1 ? ? 
ATOM   973  O O     . GLY A 1 148 ? 13.760  37.195 37.213 1.000 25.794  0 129 GLY A O     1 ? ? 
ATOM   974  N N     . LYS A 1 149 ? 12.877  35.219 37.843 1.000 26.966  0 130 LYS A N     1 ? ? 
ATOM   975  C CA    . LYS A 1 149 ? 12.542  34.804 36.493 1.000 25.536  0 130 LYS A CA    1 ? ? 
ATOM   976  C C     . LYS A 1 149 ? 11.034  34.670 36.405 1.000 23.536  0 130 LYS A C     1 ? ? 
ATOM   977  O O     . LYS A 1 149 ? 10.445  33.831 37.080 1.000 23.500  0 130 LYS A O     1 ? ? 
ATOM   978  C CB    . LYS A 1 149 ? 13.213  33.477 36.141 1.000 26.553  0 130 LYS A CB    1 ? ? 
ATOM   979  C CG    . LYS A 1 149 ? 14.729  33.530 36.123 1.000 28.933  0 130 LYS A CG    1 ? ? 
ATOM   980  C CD    . LYS A 1 149 ? 15.289  33.992 34.796 1.000 29.936  0 130 LYS A CD    1 ? ? 
ATOM   981  C CE    . LYS A 1 149 ? 16.803  33.903 34.804 1.000 30.929  0 130 LYS A CE    1 ? ? 
ATOM   982  N NZ    . LYS A 1 149 ? 17.447  34.738 33.758 1.000 31.252  0 130 LYS A NZ    1 ? ? 
ATOM   983  N N     . ASP A 1 150 ? 10.437  35.533 35.583 1.000 21.778  0 131 ASP A N     1 ? ? 
ATOM   984  C CA    . ASP A 1 150 ? 9.025   35.422 35.279 1.000 20.741  0 131 ASP A CA    1 ? ? 
ATOM   985  C C     . ASP A 1 150 ? 8.883   34.523 34.057 1.000 20.995  0 131 ASP A C     1 ? ? 
ATOM   986  O O     . ASP A 1 150 ? 9.403   34.826 32.976 1.000 20.782  0 131 ASP A O     1 ? ? 
ATOM   987  C CB    . ASP A 1 150 ? 8.385   36.786 35.039 1.000 20.137  0 131 ASP A CB    1 ? ? 
ATOM   988  C CG    . ASP A 1 150 ? 6.872   36.686 34.925 1.000 20.133  0 131 ASP A CG    1 ? ? 
ATOM   989  O OD1   . ASP A 1 150 ? 6.355   35.566 34.649 1.000 20.241  0 131 ASP A OD1   1 ? ? 
ATOM   990  O OD2   . ASP A 1 150 ? 6.207   37.719 35.170 1.000 18.618  0 131 ASP A OD2   1 ? ? 
ATOM   991  N N     . VAL A 1 151 ? 8.192   33.394 34.239 1.000 20.229  0 132 VAL A N     1 ? ? 
ATOM   992  C CA    . VAL A 1 151 ? 8.206   32.385 33.201 1.000 19.839  0 132 VAL A CA    1 ? ? 
ATOM   993  C C     . VAL A 1 151 ? 7.430   32.880 31.988 1.000 18.976  0 132 VAL A C     1 ? ? 
ATOM   994  O O     . VAL A 1 151 ? 7.564   32.314 30.916 1.000 19.205  0 132 VAL A O     1 ? ? 
ATOM   995  C CB    . VAL A 1 151 ? 7.681   31.026 33.688 1.000 19.793  0 132 VAL A CB    1 ? ? 
ATOM   996  C CG1   . VAL A 1 151 ? 8.493   30.465 34.831 1.000 20.185  0 132 VAL A CG1   1 ? ? 
ATOM   997  C CG2   . VAL A 1 151 ? 6.201   31.035 34.004 1.000 22.629  0 132 VAL A CG2   1 ? ? 
ATOM   998  N N     . PHE A 1 152 ? 6.585   33.895 32.153 1.000 18.956  0 133 PHE A N     1 ? ? 
ATOM   999  C CA    . PHE A 1 152 ? 5.798   34.338 31.015 1.000 19.987  0 133 PHE A CA    1 ? ? 
ATOM   1000 C C     . PHE A 1 152 ? 6.666   35.138 30.046 1.000 21.274  0 133 PHE A C     1 ? ? 
ATOM   1001 O O     . PHE A 1 152 ? 6.247   35.424 28.926 1.000 19.741  0 133 PHE A O     1 ? ? 
ATOM   1002 C CB    . PHE A 1 152 ? 4.535   35.067 31.486 1.000 18.953  0 133 PHE A CB    1 ? ? 
ATOM   1003 C CG    . PHE A 1 152 ? 3.576   34.165 32.210 1.000 19.377  0 133 PHE A CG    1 ? ? 
ATOM   1004 C CD1   . PHE A 1 152 ? 2.924   33.158 31.519 1.000 17.902  0 133 PHE A CD1   1 ? ? 
ATOM   1005 C CD2   . PHE A 1 152 ? 3.370   34.265 33.585 1.000 19.307  0 133 PHE A CD2   1 ? ? 
ATOM   1006 C CE1   . PHE A 1 152 ? 2.075   32.278 32.168 1.000 17.311  0 133 PHE A CE1   1 ? ? 
ATOM   1007 C CE2   . PHE A 1 152 ? 2.504   33.388 34.229 1.000 18.194  0 133 PHE A CE2   1 ? ? 
ATOM   1008 C CZ    . PHE A 1 152 ? 1.856   32.406 33.518 1.000 17.483  0 133 PHE A CZ    1 ? ? 
ATOM   1009 N N     . TYR A 1 153 ? 7.870   35.512 30.501 1.000 22.111  0 134 TYR A N     1 ? ? 
ATOM   1010 C CA    . TYR A 1 153 ? 8.812   36.274 29.696 1.000 22.469  0 134 TYR A CA    1 ? ? 
ATOM   1011 C C     . TYR A 1 153 ? 10.083  35.462 29.435 1.000 22.001  0 134 TYR A C     1 ? ? 
ATOM   1012 O O     . TYR A 1 153 ? 11.105  36.027 29.044 1.000 21.028  0 134 TYR A O     1 ? ? 
ATOM   1013 C CB    . TYR A 1 153 ? 9.144   37.605 30.379 1.000 23.952  0 134 TYR A CB    1 ? ? 
ATOM   1014 C CG    . TYR A 1 153 ? 7.952   38.494 30.619 1.000 25.823  0 134 TYR A CG    1 ? ? 
ATOM   1015 C CD1   . TYR A 1 153 ? 7.282   39.077 29.554 1.000 26.129  0 134 TYR A CD1   1 ? ? 
ATOM   1016 C CD2   . TYR A 1 153 ? 7.473   38.734 31.900 1.000 25.482  0 134 TYR A CD2   1 ? ? 
ATOM   1017 C CE1   . TYR A 1 153 ? 6.166   39.869 29.747 1.000 25.739  0 134 TYR A CE1   1 ? ? 
ATOM   1018 C CE2   . TYR A 1 153 ? 6.373   39.546 32.112 1.000 25.732  0 134 TYR A CE2   1 ? ? 
ATOM   1019 C CZ    . TYR A 1 153 ? 5.723   40.120 31.034 1.000 26.952  0 134 TYR A CZ    1 ? ? 
ATOM   1020 O OH    . TYR A 1 153 ? 4.642   40.934 31.244 1.000 26.693  0 134 TYR A OH    1 ? ? 
ATOM   1021 N N     . LEU A 1 154 ? 10.027  34.140 29.650 1.000 21.646  0 135 LEU A N     1 ? ? 
ATOM   1022 C CA    . LEU A 1 154 ? 11.148  33.244 29.369 1.000 21.476  0 135 LEU A CA    1 ? ? 
ATOM   1023 C C     . LEU A 1 154 ? 10.988  32.641 27.984 1.000 20.571  0 135 LEU A C     1 ? ? 
ATOM   1024 O O     . LEU A 1 154 ? 9.942   32.102 27.665 1.000 20.115  0 135 LEU A O     1 ? ? 
ATOM   1025 C CB    . LEU A 1 154 ? 11.174  32.097 30.381 1.000 22.220  0 135 LEU A CB    1 ? ? 
ATOM   1026 C CG    . LEU A 1 154 ? 11.970  32.336 31.648 1.000 23.878  0 135 LEU A CG    1 ? ? 
ATOM   1027 C CD1   . LEU A 1 154 ? 11.782  31.144 32.544 1.000 24.759  0 135 LEU A CD1   1 ? ? 
ATOM   1028 C CD2   . LEU A 1 154 ? 13.437  32.553 31.339 1.000 25.098  0 135 LEU A CD2   1 ? ? 
ATOM   1029 N N     . PRO A 1 155 ? 12.024  32.673 27.131 1.000 21.014  0 136 PRO A N     1 ? ? 
ATOM   1030 C CA    . PRO A 1 155 ? 11.947  31.979 25.851 1.000 20.931  0 136 PRO A CA    1 ? ? 
ATOM   1031 C C     . PRO A 1 155 ? 12.001  30.479 26.140 1.000 21.559  0 136 PRO A C     1 ? ? 
ATOM   1032 O O     . PRO A 1 155 ? 12.649  30.056 27.095 1.000 21.473  0 136 PRO A O     1 ? ? 
ATOM   1033 C CB    . PRO A 1 155 ? 13.177  32.516 25.094 1.000 19.842  0 136 PRO A CB    1 ? ? 
ATOM   1034 C CG    . PRO A 1 155 ? 14.162  32.937 26.157 1.000 19.303  0 136 PRO A CG    1 ? ? 
ATOM   1035 C CD    . PRO A 1 155 ? 13.327  33.331 27.357 1.000 20.204  0 136 PRO A CD    1 ? ? 
ATOM   1036 N N     . PRO A 1 156 ? 11.294  29.630 25.368 1.000 21.939  0 137 PRO A N     1 ? ? 
ATOM   1037 C CA    . PRO A 1 156 ? 11.381  28.182 25.552 1.000 22.086  0 137 PRO A CA    1 ? ? 
ATOM   1038 C C     . PRO A 1 156 ? 12.775  27.680 25.193 1.000 23.133  0 137 PRO A C     1 ? ? 
ATOM   1039 O O     . PRO A 1 156 ? 13.385  28.194 24.265 1.000 21.149  0 137 PRO A O     1 ? ? 
ATOM   1040 C CB    . PRO A 1 156 ? 10.315  27.590 24.625 1.000 21.524  0 137 PRO A CB    1 ? ? 
ATOM   1041 C CG    . PRO A 1 156 ? 10.073  28.679 23.635 1.000 22.025  0 137 PRO A CG    1 ? ? 
ATOM   1042 C CD    . PRO A 1 156 ? 10.339  30.007 24.317 1.000 21.514  0 137 PRO A CD    1 ? ? 
ATOM   1043 N N     . GLU A 1 157 ? 13.278  26.750 26.016 1.000 24.020  0 138 GLU A N     1 ? ? 
ATOM   1044 C CA    . GLU A 1 157 ? 14.541  26.053 25.815 1.000 25.415  0 138 GLU A CA    1 ? ? 
ATOM   1045 C C     . GLU A 1 157 ? 14.293  24.575 25.500 1.000 26.408  0 138 GLU A C     1 ? ? 
ATOM   1046 O O     . GLU A 1 157 ? 13.206  24.040 25.743 1.000 26.975  0 138 GLU A O     1 ? ? 
ATOM   1047 C CB    . GLU A 1 157 ? 15.398  26.156 27.080 1.000 24.348  0 138 GLU A CB    1 ? ? 
ATOM   1048 C CG    . GLU A 1 157 ? 15.261  27.497 27.786 1.000 25.642  0 138 GLU A CG    1 ? ? 
ATOM   1049 C CD    . GLU A 1 157 ? 15.743  27.469 29.230 1.000 26.228  0 138 GLU A CD    1 ? ? 
ATOM   1050 O OE1   . GLU A 1 157 ? 16.900  27.145 29.487 1.000 27.530  0 138 GLU A OE1   1 ? ? 
ATOM   1051 O OE2   . GLU A 1 157 ? 14.918  27.750 30.098 1.000 26.123  0 138 GLU A OE2   1 ? ? 
ATOM   1052 N N     . LYS A 1 158 ? 15.334  23.904 24.991 1.000 27.880  0 139 LYS A N     1 ? ? 
ATOM   1053 C CA    . LYS A 1 158 ? 15.243  22.472 24.747 1.000 29.704  0 139 LYS A CA    1 ? ? 
ATOM   1054 C C     . LYS A 1 158 ? 15.320  21.742 26.078 1.000 30.042  0 139 LYS A C     1 ? ? 
ATOM   1055 O O     . LYS A 1 158 ? 16.125  22.118 26.928 1.000 30.514  0 139 LYS A O     1 ? ? 
ATOM   1056 C CB    . LYS A 1 158 ? 16.382  21.967 23.859 1.000 30.858  0 139 LYS A CB    1 ? ? 
ATOM   1057 C CG    . LYS A 1 158 ? 16.332  22.412 22.402 1.000 33.815  0 139 LYS A CG    1 ? ? 
ATOM   1058 C CD    . LYS A 1 158 ? 17.354  21.691 21.552 1.000 34.560  0 139 LYS A CD    1 ? ? 
ATOM   1059 C CE    . LYS A 1 158 ? 16.812  20.471 20.833 1.000 36.160  0 139 LYS A CE    1 ? ? 
ATOM   1060 N NZ    . LYS A 1 158 ? 16.356  20.803 19.462 1.000 34.927  0 139 LYS A NZ    1 ? ? 
ATOM   1061 N N     . CYS A 1 159 ? 14.444  20.747 26.249 1.000 28.558  0 140 CYS A N     1 ? ? 
ATOM   1062 C CA    . CYS A 1 159 ? 14.448  19.937 27.450 1.000 26.836  0 140 CYS A CA    1 ? ? 
ATOM   1063 C C     . CYS A 1 159 ? 13.769  18.601 27.168 1.000 26.559  0 140 CYS A C     1 ? ? 
ATOM   1064 O O     . CYS A 1 159 ? 13.018  18.476 26.200 1.000 29.661  0 140 CYS A O     1 ? ? 
ATOM   1065 C CB    . CYS A 1 159 ? 13.755  20.657 28.599 1.000 26.005  0 140 CYS A CB    1 ? ? 
ATOM   1066 S SG    . CYS A 1 159 ? 11.987  20.948 28.329 1.000 27.248  0 140 CYS A SG    1 ? ? 
ATOM   1067 N N     . ASP A 1 160 ? 14.045  17.619 28.041 1.000 25.301  0 141 ASP A N     1 ? ? 
ATOM   1068 C CA    . ASP A 1 160 ? 13.551  16.255 27.902 1.000 24.650  0 141 ASP A CA    1 ? ? 
ATOM   1069 C C     . ASP A 1 160 ? 12.398  16.008 28.879 1.000 24.517  0 141 ASP A C     1 ? ? 
ATOM   1070 O O     . ASP A 1 160 ? 11.577  15.113 28.663 1.000 24.040  0 141 ASP A O     1 ? ? 
ATOM   1071 C CB    . ASP A 1 160 ? 14.669  15.227 28.098 1.000 24.284  0 141 ASP A CB    1 ? ? 
ATOM   1072 C CG    . ASP A 1 160 ? 15.912  15.499 27.268 1.000 23.946  0 141 ASP A CG    1 ? ? 
ATOM   1073 O OD1   . ASP A 1 160 ? 15.842  15.317 26.025 1.000 23.785  0 141 ASP A OD1   1 ? ? 
ATOM   1074 O OD2   . ASP A 1 160 ? 16.943  15.889 27.861 1.000 23.478  0 141 ASP A OD2   1 ? ? 
ATOM   1075 N N     . THR A 1 161 ? 12.333  16.820 29.947 1.000 23.452  0 142 THR A N     1 ? ? 
ATOM   1076 C CA    . THR A 1 161 ? 11.220  16.804 30.888 1.000 21.932  0 142 THR A CA    1 ? ? 
ATOM   1077 C C     . THR A 1 161 ? 10.826  18.245 31.209 1.000 21.213  0 142 THR A C     1 ? ? 
ATOM   1078 O O     . THR A 1 161 ? 11.676  19.022 31.640 1.000 19.575  0 142 THR A O     1 ? ? 
ATOM   1079 C CB    . THR A 1 161 ? 11.616  16.133 32.208 1.000 21.404  0 142 THR A CB    1 ? ? 
ATOM   1080 O OG1   . THR A 1 161 ? 12.277  14.914 31.892 1.000 20.057  0 142 THR A OG1   1 ? ? 
ATOM   1081 C CG2   . THR A 1 161 ? 10.435  15.841 33.108 1.000 20.959  0 142 THR A CG2   1 ? ? 
ATOM   1082 N N     . LEU A 1 162 ? 9.537   18.574 31.022 1.000 20.981  0 143 LEU A N     1 ? ? 
ATOM   1083 C CA    . LEU A 1 162 ? 9.011   19.886 31.371 1.000 19.814  0 143 LEU A CA    1 ? ? 
ATOM   1084 C C     . LEU A 1 162 ? 8.106   19.761 32.590 1.000 18.792  0 143 LEU A C     1 ? ? 
ATOM   1085 O O     . LEU A 1 162 ? 7.066   19.118 32.511 1.000 18.419  0 143 LEU A O     1 ? ? 
ATOM   1086 C CB    . LEU A 1 162 ? 8.230   20.439 30.171 1.000 20.038  0 143 LEU A CB    1 ? ? 
ATOM   1087 C CG    . LEU A 1 162 ? 7.833   21.918 30.233 1.000 20.303  0 143 LEU A CG    1 ? ? 
ATOM   1088 C CD1   . LEU A 1 162 ? 6.651   22.135 31.170 1.000 20.379  0 143 LEU A CD1   1 ? ? 
ATOM   1089 C CD2   . LEU A 1 162 ? 9.000   22.819 30.650 1.000 20.182  0 143 LEU A CD2   1 ? ? 
ATOM   1090 N N     . LEU A 1 163 ? 8.523   20.355 33.709 1.000 17.908  0 144 LEU A N     1 ? ? 
ATOM   1091 C CA    . LEU A 1 163 ? 7.669   20.410 34.880 1.000 18.451  0 144 LEU A CA    1 ? ? 
ATOM   1092 C C     . LEU A 1 163 ? 7.192   21.841 35.069 1.000 19.472  0 144 LEU A C     1 ? ? 
ATOM   1093 O O     . LEU A 1 163 ? 7.936   22.787 34.812 1.000 20.479  0 144 LEU A O     1 ? ? 
ATOM   1094 C CB    . LEU A 1 163 ? 8.431   19.941 36.114 1.000 17.655  0 144 LEU A CB    1 ? ? 
ATOM   1095 C CG    . LEU A 1 163 ? 9.209   18.646 35.975 1.000 17.865  0 144 LEU A CG    1 ? ? 
ATOM   1096 C CD1   . LEU A 1 163 ? 10.053  18.457 37.213 1.000 17.209  0 144 LEU A CD1   1 ? ? 
ATOM   1097 C CD2   . LEU A 1 163 ? 8.267   17.465 35.817 1.000 18.720  0 144 LEU A CD2   1 ? ? 
ATOM   1098 N N     . CYS A 1 164 ? 5.943   21.987 35.527 1.000 20.968  0 145 CYS A N     1 ? ? 
ATOM   1099 C CA    . CYS A 1 164 ? 5.405   23.304 35.831 1.000 20.139  0 145 CYS A CA    1 ? ? 
ATOM   1100 C C     . CYS A 1 164 ? 4.362   23.180 36.927 1.000 20.990  0 145 CYS A C     1 ? ? 
ATOM   1101 O O     . CYS A 1 164 ? 3.456   22.367 36.798 1.000 21.683  0 145 CYS A O     1 ? ? 
ATOM   1102 C CB    . CYS A 1 164 ? 4.768   23.914 34.592 1.000 19.495  0 145 CYS A CB    1 ? ? 
ATOM   1103 S SG    . CYS A 1 164 ? 4.158   25.590 34.863 1.000 21.092  0 145 CYS A SG    1 ? ? 
ATOM   1104 N N     . ASP A 1 165 ? 4.502   24.005 37.974 1.000 21.186  0 146 ASP A N     1 ? ? 
ATOM   1105 C CA    . ASP A 1 165 ? 3.691   23.948 39.182 1.000 21.032  0 146 ASP A CA    1 ? ? 
ATOM   1106 C C     . ASP A 1 165 ? 3.081   25.322 39.499 1.000 22.303  0 146 ASP A C     1 ? ? 
ATOM   1107 O O     . ASP A 1 165 ? 2.799   25.627 40.665 1.000 23.664  0 146 ASP A O     1 ? ? 
ATOM   1108 C CB    . ASP A 1 165 ? 4.518   23.350 40.324 1.000 20.977  0 146 ASP A CB    1 ? ? 
ATOM   1109 C CG    . ASP A 1 165 ? 3.702   22.882 41.517 1.000 21.874  0 146 ASP A CG    1 ? ? 
ATOM   1110 O OD1   . ASP A 1 165 ? 2.454   22.809 41.398 1.000 21.944  0 146 ASP A OD1   1 ? ? 
ATOM   1111 O OD2   . ASP A 1 165 ? 4.310   22.638 42.577 1.000 23.634  0 146 ASP A OD2   1 ? ? 
ATOM   1112 N N     . ILE A 1 166 ? 2.840   26.126 38.449 1.000 21.147  0 147 ILE A N     1 ? ? 
ATOM   1113 C CA    . ILE A 1 166 ? 2.351   27.484 38.599 1.000 20.724  0 147 ILE A CA    1 ? ? 
ATOM   1114 C C     . ILE A 1 166 ? 0.825   27.503 38.511 1.000 22.079  0 147 ILE A C     1 ? ? 
ATOM   1115 O O     . ILE A 1 166 ? 0.220   26.814 37.685 1.000 21.727  0 147 ILE A O     1 ? ? 
ATOM   1116 C CB    . ILE A 1 166 ? 2.987   28.408 37.541 1.000 20.155  0 147 ILE A CB    1 ? ? 
ATOM   1117 C CG1   . ILE A 1 166 ? 4.498   28.507 37.750 1.000 19.949  0 147 ILE A CG1   1 ? ? 
ATOM   1118 C CG2   . ILE A 1 166 ? 2.311   29.783 37.519 1.000 18.987  0 147 ILE A CG2   1 ? ? 
ATOM   1119 C CD1   . ILE A 1 166 ? 5.268   29.143 36.616 1.000 20.018  0 147 ILE A CD1   1 ? ? 
ATOM   1120 N N     . GLY A 1 167 ? 0.232   28.363 39.341 1.000 22.401  0 148 GLY A N     1 ? ? 
ATOM   1121 C CA    . GLY A 1 167 ? -1.201  28.573 39.380 1.000 25.070  0 148 GLY A CA    1 ? ? 
ATOM   1122 C C     . GLY A 1 167 ? -1.596  29.072 40.765 1.000 27.753  0 148 GLY A C     1 ? ? 
ATOM   1123 O O     . GLY A 1 167 ? -1.615  28.309 41.728 1.000 28.169  0 148 GLY A O     1 ? ? 
ATOM   1124 N N     . GLU A 1 168 ? -1.892  30.368 40.863 1.000 30.576  0 149 GLU A N     1 ? ? 
ATOM   1125 C CA    . GLU A 1 168 ? -2.222  30.969 42.142 1.000 32.717  0 149 GLU A CA    1 ? ? 
ATOM   1126 C C     . GLU A 1 168 ? -3.734  30.919 42.327 1.000 31.376  0 149 GLU A C     1 ? ? 
ATOM   1127 O O     . GLU A 1 168 ? -4.487  31.372 41.463 1.000 31.014  0 149 GLU A O     1 ? ? 
ATOM   1128 C CB    . GLU A 1 168 ? -1.701  32.404 42.169 1.000 38.179  0 149 GLU A CB    1 ? ? 
ATOM   1129 C CG    . GLU A 1 168 ? -1.933  33.116 43.492 1.000 45.773  0 149 GLU A CG    1 ? ? 
ATOM   1130 C CD    . GLU A 1 168 ? -1.507  34.575 43.592 1.000 49.925  0 149 GLU A CD    1 ? ? 
ATOM   1131 O OE1   . GLU A 1 168 ? -2.337  35.430 43.955 1.000 47.782  0 149 GLU A OE1   1 ? ? 
ATOM   1132 O OE2   . GLU A 1 168 ? -0.322  34.860 43.353 1.000 55.145  0 149 GLU A OE2   1 ? ? 
ATOM   1133 N N     . SER A 1 169 ? -4.169  30.392 43.475 1.000 30.717  0 150 SER A N     1 ? ? 
ATOM   1134 C CA    . SER A 1 169 ? -5.583  30.331 43.809 1.000 30.460  0 150 SER A CA    1 ? ? 
ATOM   1135 C C     . SER A 1 169 ? -6.165  31.730 43.993 1.000 29.906  0 150 SER A C     1 ? ? 
ATOM   1136 O O     . SER A 1 169 ? -5.479  32.629 44.461 1.000 30.571  0 150 SER A O     1 ? ? 
ATOM   1137 C CB    . SER A 1 169 ? -5.817  29.484 45.022 1.000 30.592  0 150 SER A CB    1 ? ? 
ATOM   1138 O OG    . SER A 1 169 ? -5.584  28.114 44.715 1.000 31.359  0 150 SER A OG    1 ? ? 
ATOM   1139 N N     . SER A 1 170 ? -7.446  31.875 43.616 1.000 27.913  0 151 SER A N     1 ? ? 
ATOM   1140 C CA    . SER A 1 170 ? -8.223  33.090 43.798 1.000 26.795  0 151 SER A CA    1 ? ? 
ATOM   1141 C C     . SER A 1 170 ? -9.628  32.672 44.192 1.000 27.040  0 151 SER A C     1 ? ? 
ATOM   1142 O O     . SER A 1 170 ? -10.072 31.598 43.793 1.000 28.025  0 151 SER A O     1 ? ? 
ATOM   1143 C CB    . SER A 1 170 ? -8.274  33.885 42.528 1.000 25.246  0 151 SER A CB    1 ? ? 
ATOM   1144 O OG    . SER A 1 170 ? -9.407  34.748 42.484 1.000 23.255  0 151 SER A OG    1 ? ? 
ATOM   1145 N N     . PRO A 1 171 ? -10.365 33.449 45.018 1.000 28.294  0 152 PRO A N     1 ? ? 
ATOM   1146 C CA    . PRO A 1 171 ? -11.785 33.175 45.252 1.000 26.707  0 152 PRO A CA    1 ? ? 
ATOM   1147 C C     . PRO A 1 171 ? -12.617 33.177 43.980 1.000 24.804  0 152 PRO A C     1 ? ? 
ATOM   1148 O O     . PRO A 1 171 ? -13.610 32.464 43.904 1.000 24.791  0 152 PRO A O     1 ? ? 
ATOM   1149 C CB    . PRO A 1 171 ? -12.244 34.278 46.208 1.000 26.156  0 152 PRO A CB    1 ? ? 
ATOM   1150 C CG    . PRO A 1 171 ? -10.976 34.641 46.939 1.000 28.043  0 152 PRO A CG    1 ? ? 
ATOM   1151 C CD    . PRO A 1 171 ? -9.865  34.498 45.917 1.000 29.041  0 152 PRO A CD    1 ? ? 
ATOM   1152 N N     . SER A 1 172 ? -12.162 33.940 42.979 1.000 25.093  0 153 SER A N     1 ? ? 
ATOM   1153 C CA    . SER A 1 172 ? -12.850 34.048 41.705 1.000 24.028  0 153 SER A CA    1 ? ? 
ATOM   1154 C C     . SER A 1 172 ? -12.391 32.926 40.785 1.000 24.508  0 153 SER A C     1 ? ? 
ATOM   1155 O O     . SER A 1 172 ? -11.210 32.844 40.449 1.000 25.107  0 153 SER A O     1 ? ? 
ATOM   1156 C CB    . SER A 1 172 ? -12.609 35.387 41.074 1.000 22.734  0 153 SER A CB    1 ? ? 
ATOM   1157 O OG    . SER A 1 172 ? -12.927 35.356 39.691 1.000 21.558  0 153 SER A OG    1 ? ? 
ATOM   1158 N N     . PRO A 1 173 ? -13.305 32.038 40.338 1.000 25.710  0 154 PRO A N     1 ? ? 
ATOM   1159 C CA    . PRO A 1 173 ? -12.946 31.029 39.341 1.000 26.242  0 154 PRO A CA    1 ? ? 
ATOM   1160 C C     . PRO A 1 173 ? -12.609 31.613 37.971 1.000 26.257  0 154 PRO A C     1 ? ? 
ATOM   1161 O O     . PRO A 1 173 ? -11.825 31.032 37.234 1.000 25.103  0 154 PRO A O     1 ? ? 
ATOM   1162 C CB    . PRO A 1 173 ? -14.178 30.117 39.267 1.000 26.153  0 154 PRO A CB    1 ? ? 
ATOM   1163 C CG    . PRO A 1 173 ? -15.312 30.992 39.741 1.000 25.476  0 154 PRO A CG    1 ? ? 
ATOM   1164 C CD    . PRO A 1 173 ? -14.704 31.919 40.780 1.000 24.640  0 154 PRO A CD    1 ? ? 
ATOM   1165 N N     . THR A 1 174 ? -13.181 32.768 37.627 1.000 28.253  0 155 THR A N     1 ? ? 
ATOM   1166 C CA    . THR A 1 174 ? -12.861 33.373 36.344 1.000 30.113  0 155 THR A CA    1 ? ? 
ATOM   1167 C C     . THR A 1 174 ? -11.413 33.861 36.355 1.000 30.622  0 155 THR A C     1 ? ? 
ATOM   1168 O O     . THR A 1 174 ? -10.727 33.747 35.348 1.000 33.326  0 155 THR A O     1 ? ? 
ATOM   1169 C CB    . THR A 1 174 ? -13.861 34.465 35.962 1.000 30.717  0 155 THR A CB    1 ? ? 
ATOM   1170 O OG1   . THR A 1 174 ? -13.613 35.499 36.908 1.000 34.824  0 155 THR A OG1   1 ? ? 
ATOM   1171 C CG2   . THR A 1 174 ? -15.296 33.986 36.010 1.000 30.936  0 155 THR A CG2   1 ? ? 
ATOM   1172 N N     . VAL A 1 175 ? -10.942 34.362 37.501 1.000 29.059  0 156 VAL A N     1 ? ? 
ATOM   1173 C CA    . VAL A 1 175 ? -9.551  34.763 37.640 1.000 27.979  0 156 VAL A CA    1 ? ? 
ATOM   1174 C C     . VAL A 1 175 ? -8.666  33.527 37.477 1.000 28.541  0 156 VAL A C     1 ? ? 
ATOM   1175 O O     . VAL A 1 175 ? -7.723  33.510 36.682 1.000 28.013  0 156 VAL A O     1 ? ? 
ATOM   1176 C CB    . VAL A 1 175 ? -9.302  35.476 38.984 1.000 26.954  0 156 VAL A CB    1 ? ? 
ATOM   1177 C CG1   . VAL A 1 175 ? -7.823  35.707 39.224 1.000 24.646  0 156 VAL A CG1   1 ? ? 
ATOM   1178 C CG2   . VAL A 1 175 ? -10.041 36.805 39.059 1.000 26.267  0 156 VAL A CG2   1 ? ? 
ATOM   1179 N N     . GLU A 1 176 ? -9.027  32.468 38.199 1.000 28.065  0 157 GLU A N     1 ? ? 
ATOM   1180 C CA    . GLU A 1 176 ? -8.322  31.201 38.124 1.000 27.122  0 157 GLU A CA    1 ? ? 
ATOM   1181 C C     . GLU A 1 176 ? -8.329  30.631 36.709 1.000 25.505  0 157 GLU A C     1 ? ? 
ATOM   1182 O O     . GLU A 1 176 ? -7.354  30.017 36.294 1.000 24.742  0 157 GLU A O     1 ? ? 
ATOM   1183 C CB    . GLU A 1 176 ? -8.945  30.214 39.097 1.000 27.348  0 157 GLU A CB    1 ? ? 
ATOM   1184 C CG    . GLU A 1 176 ? -8.646  30.571 40.525 1.000 28.921  0 157 GLU A CG    1 ? ? 
ATOM   1185 C CD    . GLU A 1 176 ? -9.078  29.450 41.440 1.000 30.599  0 157 GLU A CD    1 ? ? 
ATOM   1186 O OE1   . GLU A 1 176 ? -9.953  28.672 41.018 1.000 31.370  0 157 GLU A OE1   1 ? ? 
ATOM   1187 O OE2   . GLU A 1 176 ? -8.542  29.354 42.559 1.000 30.969  0 157 GLU A OE2   1 ? ? 
ATOM   1188 N N     . GLU A 1 177 ? -9.453  30.773 36.009 1.000 24.792  0 158 GLU A N     1 ? ? 
ATOM   1189 C CA    . GLU A 1 177 ? -9.593  30.347 34.625 1.000 24.212  0 158 GLU A CA    1 ? ? 
ATOM   1190 C C     . GLU A 1 177 ? -8.565  31.072 33.757 1.000 22.897  0 158 GLU A C     1 ? ? 
ATOM   1191 O O     . GLU A 1 177 ? -7.939  30.489 32.881 1.000 22.545  0 158 GLU A O     1 ? ? 
ATOM   1192 C CB    . GLU A 1 177 ? -11.018 30.629 34.147 1.000 25.461  0 158 GLU A CB    1 ? ? 
ATOM   1193 C CG    . GLU A 1 177 ? -11.176 30.510 32.648 1.000 29.690  0 158 GLU A CG    1 ? ? 
ATOM   1194 C CD    . GLU A 1 177 ? -12.593 30.537 32.118 1.000 33.344  0 158 GLU A CD    1 ? ? 
ATOM   1195 O OE1   . GLU A 1 177 ? -13.237 31.583 32.188 1.000 36.392  0 158 GLU A OE1   1 ? ? 
ATOM   1196 O OE2   . GLU A 1 177 ? -13.070 29.484 31.726 1.000 36.567  0 158 GLU A OE2   1 ? ? 
ATOM   1197 N N     . SER A 1 178 ? -8.405  32.367 33.990 1.000 21.817  0 159 SER A N     1 ? ? 
ATOM   1198 C CA    . SER A 1 178 ? -7.497  33.126 33.162 1.000 21.939  0 159 SER A CA    1 ? ? 
ATOM   1199 C C     . SER A 1 178 ? -6.051  32.719 33.448 1.000 22.684  0 159 SER A C     1 ? ? 
ATOM   1200 O O     . SER A 1 178 ? -5.304  32.482 32.509 1.000 23.188  0 159 SER A O     1 ? ? 
ATOM   1201 C CB    . SER A 1 178 ? -7.748  34.572 33.349 1.000 20.858  0 159 SER A CB    1 ? ? 
ATOM   1202 O OG    . SER A 1 178 ? -6.735  35.282 32.712 1.000 21.739  0 159 SER A OG    1 ? ? 
ATOM   1203 N N     . ARG A 1 179 ? -5.682  32.608 34.735 1.000 23.614  0 160 ARG A N     1 ? ? 
ATOM   1204 C CA    . ARG A 1 179 ? -4.364  32.151 35.167 1.000 23.335  0 160 ARG A CA    1 ? ? 
ATOM   1205 C C     . ARG A 1 179 ? -4.044  30.770 34.596 1.000 22.715  0 160 ARG A C     1 ? ? 
ATOM   1206 O O     . ARG A 1 179 ? -2.915  30.517 34.209 1.000 23.427  0 160 ARG A O     1 ? ? 
ATOM   1207 C CB    . ARG A 1 179 ? -4.255  32.119 36.698 1.000 22.873  0 160 ARG A CB    1 ? ? 
ATOM   1208 C CG    . ARG A 1 179 ? -4.182  33.496 37.334 1.000 23.114  0 160 ARG A CG    1 ? ? 
ATOM   1209 C CD    . ARG A 1 179 ? -4.129  33.428 38.841 1.000 23.872  0 160 ARG A CD    1 ? ? 
ATOM   1210 N NE    . ARG A 1 179 ? -4.348  34.754 39.405 1.000 25.680  0 160 ARG A NE    1 ? ? 
ATOM   1211 C CZ    . ARG A 1 179 ? -4.598  35.007 40.685 1.000 26.043  0 160 ARG A CZ    1 ? ? 
ATOM   1212 N NH1   . ARG A 1 179 ? -4.825  36.226 41.094 1.000 25.555  0 160 ARG A NH1   1 ? ? 
ATOM   1213 N NH2   . ARG A 1 179 ? -4.713  34.040 41.567 1.000 26.787  0 160 ARG A NH2   1 ? ? 
ATOM   1214 N N     . THR A 1 180 ? -5.036  29.880 34.558 1.000 22.590  0 161 THR A N     1 ? ? 
ATOM   1215 C CA    . THR A 1 180 ? -4.818  28.525 34.076 1.000 22.635  0 161 THR A CA    1 ? ? 
ATOM   1216 C C     . THR A 1 180 ? -4.517  28.547 32.577 1.000 23.179  0 161 THR A C     1 ? ? 
ATOM   1217 O O     . THR A 1 180 ? -3.538  27.949 32.153 1.000 25.471  0 161 THR A O     1 ? ? 
ATOM   1218 C CB    . THR A 1 180 ? -5.986  27.608 34.465 1.000 22.638  0 161 THR A CB    1 ? ? 
ATOM   1219 O OG1   . THR A 1 180 ? -6.183  27.621 35.887 1.000 21.312  0 161 THR A OG1   1 ? ? 
ATOM   1220 C CG2   . THR A 1 180 ? -5.776  26.178 34.025 1.000 22.531  0 161 THR A CG2   1 ? ? 
ATOM   1221 N N     . ILE A 1 181 ? -5.320  29.269 31.787 1.000 23.451  0 162 ILE A N     1 ? ? 
ATOM   1222 C CA    . ILE A 1 181 ? -5.118  29.355 30.343 1.000 23.853  0 162 ILE A CA    1 ? ? 
ATOM   1223 C C     . ILE A 1 181 ? -3.753  29.965 30.041 1.000 25.711  0 162 ILE A C     1 ? ? 
ATOM   1224 O O     . ILE A 1 181 ? -3.053  29.535 29.129 1.000 25.477  0 162 ILE A O     1 ? ? 
ATOM   1225 C CB    . ILE A 1 181 ? -6.263  30.121 29.650 1.000 23.311  0 162 ILE A CB    1 ? ? 
ATOM   1226 C CG1   . ILE A 1 181 ? -7.541  29.298 29.767 1.000 23.675  0 162 ILE A CG1   1 ? ? 
ATOM   1227 C CG2   . ILE A 1 181 ? -5.928  30.451 28.197 1.000 23.375  0 162 ILE A CG2   1 ? ? 
ATOM   1228 C CD1   . ILE A 1 181 ? -8.819  30.091 29.651 1.000 24.237  0 162 ILE A CD1   1 ? ? 
ATOM   1229 N N     . ARG A 1 182 ? -3.362  30.965 30.831 1.000 29.066  0 163 ARG A N     1 ? ? 
ATOM   1230 C CA    . ARG A 1 182 ? -2.094  31.625 30.598 1.000 32.045  0 163 ARG A CA    1 ? ? 
ATOM   1231 C C     . ARG A 1 182 ? -0.974  30.602 30.725 1.000 31.036  0 163 ARG A C     1 ? ? 
ATOM   1232 O O     . ARG A 1 182 ? -0.060  30.592 29.907 1.000 30.031  0 163 ARG A O     1 ? ? 
ATOM   1233 C CB    . ARG A 1 182 ? -1.899  32.737 31.625 1.000 36.283  0 163 ARG A CB    1 ? ? 
ATOM   1234 C CG    . ARG A 1 182 ? -1.043  33.887 31.158 1.000 43.967  0 163 ARG A CG    1 ? ? 
ATOM   1235 C CD    . ARG A 1 182 ? -0.628  33.920 29.696 1.000 54.590  0 163 ARG A CD    1 ? ? 
ATOM   1236 N NE    . ARG A 1 182 ? 0.337   34.858 29.079 1.000 60.641  0 163 ARG A NE    1 ? ? 
ATOM   1237 C CZ    . ARG A 1 182 ? 1.093   35.840 29.630 1.000 63.247  0 163 ARG A CZ    1 ? ? 
ATOM   1238 N NH1   . ARG A 1 182 ? 1.113   36.062 30.937 1.000 62.274  0 163 ARG A NH1   1 ? ? 
ATOM   1239 N NH2   . ARG A 1 182 ? 1.886   36.568 28.862 1.000 58.105  0 163 ARG A NH2   1 ? ? 
ATOM   1240 N N     . VAL A 1 183 ? -1.047  29.770 31.772 1.000 28.350  0 164 VAL A N     1 ? ? 
ATOM   1241 C CA    . VAL A 1 183 ? -0.061  28.726 31.998 1.000 25.127  0 164 VAL A CA    1 ? ? 
ATOM   1242 C C     . VAL A 1 183 ? -0.055  27.758 30.823 1.000 25.216  0 164 VAL A C     1 ? ? 
ATOM   1243 O O     . VAL A 1 183 ? 1.016   27.390 30.360 1.000 23.466  0 164 VAL A O     1 ? ? 
ATOM   1244 C CB    . VAL A 1 183 ? -0.289  27.990 33.329 1.000 22.595  0 164 VAL A CB    1 ? ? 
ATOM   1245 C CG1   . VAL A 1 183 ? 0.433   26.654 33.374 1.000 21.842  0 164 VAL A CG1   1 ? ? 
ATOM   1246 C CG2   . VAL A 1 183 ? 0.148   28.849 34.493 1.000 22.102  0 164 VAL A CG2   1 ? ? 
ATOM   1247 N N     . LEU A 1 184 ? -1.246  27.355 30.362 1.000 25.266  0 165 LEU A N     1 ? ? 
ATOM   1248 C CA    . LEU A 1 184 ? -1.325  26.327 29.332 1.000 26.853  0 165 LEU A CA    1 ? ? 
ATOM   1249 C C     . LEU A 1 184 ? -0.741  26.860 28.019 1.000 28.474  0 165 LEU A C     1 ? ? 
ATOM   1250 O O     . LEU A 1 184 ? 0.037   26.174 27.361 1.000 29.002  0 165 LEU A O     1 ? ? 
ATOM   1251 C CB    . LEU A 1 184 ? -2.764  25.830 29.169 1.000 25.170  0 165 LEU A CB    1 ? ? 
ATOM   1252 C CG    . LEU A 1 184 ? -3.339  24.995 30.320 1.000 26.232  0 165 LEU A CG    1 ? ? 
ATOM   1253 C CD1   . LEU A 1 184 ? -4.814  24.721 30.093 1.000 24.970  0 165 LEU A CD1   1 ? ? 
ATOM   1254 C CD2   . LEU A 1 184 ? -2.593  23.688 30.536 1.000 23.535  0 165 LEU A CD2   1 ? ? 
ATOM   1255 N N     . LYS A 1 185 ? -1.023  28.128 27.704 1.000 28.645  0 166 LYS A N     1 ? ? 
ATOM   1256 C CA    . LYS A 1 185 ? -0.480  28.734 26.499 1.000 26.512  0 166 LYS A CA    1 ? ? 
ATOM   1257 C C     . LYS A 1 185 ? 1.028   28.884 26.605 1.000 25.284  0 166 LYS A C     1 ? ? 
ATOM   1258 O O     . LYS A 1 185 ? 1.716   28.732 25.613 1.000 24.909  0 166 LYS A O     1 ? ? 
ATOM   1259 C CB    . LYS A 1 185 ? -1.109  30.099 26.250 1.000 29.261  0 166 LYS A CB    1 ? ? 
ATOM   1260 C CG    . LYS A 1 185 ? -2.572  30.009 25.876 1.000 31.203  0 166 LYS A CG    1 ? ? 
ATOM   1261 C CD    . LYS A 1 185 ? -3.113  31.301 25.366 1.000 35.171  0 166 LYS A CD    1 ? ? 
ATOM   1262 C CE    . LYS A 1 185 ? -3.865  30.950 24.096 1.000 36.245  0 166 LYS A CE    1 ? ? 
ATOM   1263 N NZ    . LYS A 1 185 ? -3.829  31.944 22.989 1.000 34.924  0 166 LYS A NZ    1 ? ? 
ATOM   1264 N N     . MET A 1 186 ? 1.522   29.164 27.811 1.000 24.230  0 167 MET A N     1 ? ? 
ATOM   1265 C CA    . MET A 1 186 ? 2.939   29.379 28.054 1.000 23.037  0 167 MET A CA    1 ? ? 
ATOM   1266 C C     . MET A 1 186 ? 3.702   28.067 27.895 1.000 22.486  0 167 MET A C     1 ? ? 
ATOM   1267 O O     . MET A 1 186 ? 4.776   28.096 27.303 1.000 23.676  0 167 MET A O     1 ? ? 
ATOM   1268 C CB    . MET A 1 186 ? 3.156   30.017 29.436 1.000 22.029  0 167 MET A CB    1 ? ? 
ATOM   1269 C CG    . MET A 1 186 ? 4.578   30.224 29.867 1.000 20.130  0 167 MET A CG    1 ? ? 
ATOM   1270 S SD    . MET A 1 186 ? 5.235   28.785 30.716 1.000 20.562  0 167 MET A SD    1 ? ? 
ATOM   1271 C CE    . MET A 1 186 ? 4.291   28.781 32.238 1.000 19.609  0 167 MET A CE    1 ? ? 
ATOM   1272 N N     . VAL A 1 187 ? 3.161   26.952 28.414 1.000 22.213  0 168 VAL A N     1 ? ? 
ATOM   1273 C CA    . VAL A 1 187 ? 3.924   25.711 28.481 1.000 21.453  0 168 VAL A CA    1 ? ? 
ATOM   1274 C C     . VAL A 1 187 ? 4.029   25.047 27.110 1.000 22.232  0 168 VAL A C     1 ? ? 
ATOM   1275 O O     . VAL A 1 187 ? 4.961   24.295 26.872 1.000 22.851  0 168 VAL A O     1 ? ? 
ATOM   1276 C CB    . VAL A 1 187 ? 3.412   24.719 29.545 1.000 19.448  0 168 VAL A CB    1 ? ? 
ATOM   1277 C CG1   . VAL A 1 187 ? 3.479   25.286 30.953 1.000 18.165  0 168 VAL A CG1   1 ? ? 
ATOM   1278 C CG2   . VAL A 1 187 ? 2.036   24.180 29.219 1.000 19.676  0 168 VAL A CG2   1 ? ? 
ATOM   1279 N N     . GLU A 1 188 ? 3.091   25.314 26.207 1.000 24.271  0 169 GLU A N     1 ? ? 
ATOM   1280 C CA    . GLU A 1 188 ? 2.973   24.517 24.994 1.000 26.122  0 169 GLU A CA    1 ? ? 
ATOM   1281 C C     . GLU A 1 188 ? 4.274   24.543 24.181 1.000 26.330  0 169 GLU A C     1 ? ? 
ATOM   1282 O O     . GLU A 1 188 ? 4.727   23.501 23.717 1.000 25.368  0 169 GLU A O     1 ? ? 
ATOM   1283 C CB    . GLU A 1 188 ? 1.732   24.928 24.197 1.000 28.253  0 169 GLU A CB    1 ? ? 
ATOM   1284 C CG    . GLU A 1 188 ? 1.489   24.060 22.968 1.000 30.110  0 169 GLU A CG    1 ? ? 
ATOM   1285 C CD    . GLU A 1 188 ? 0.207   24.397 22.231 1.000 32.167  0 169 GLU A CD    1 ? ? 
ATOM   1286 O OE1   . GLU A 1 188 ? -0.320  23.557 21.528 1.000 34.310  0 169 GLU A OE1   1 ? ? 
ATOM   1287 O OE2   . GLU A 1 188 ? -0.294  25.497 22.441 1.000 32.302  0 169 GLU A OE2   1 ? ? 
ATOM   1288 N N     . PRO A 1 189 ? 4.924   25.709 23.942 1.000 25.431  0 170 PRO A N     1 ? ? 
ATOM   1289 C CA    . PRO A 1 189 ? 6.181   25.746 23.189 1.000 25.627  0 170 PRO A CA    1 ? ? 
ATOM   1290 C C     . PRO A 1 189 ? 7.346   24.968 23.807 1.000 26.380  0 170 PRO A C     1 ? ? 
ATOM   1291 O O     . PRO A 1 189 ? 8.346   24.693 23.153 1.000 29.606  0 170 PRO A O     1 ? ? 
ATOM   1292 C CB    . PRO A 1 189 ? 6.534   27.241 23.114 1.000 25.674  0 170 PRO A CB    1 ? ? 
ATOM   1293 C CG    . PRO A 1 189 ? 5.211   27.950 23.333 1.000 25.721  0 170 PRO A CG    1 ? ? 
ATOM   1294 C CD    . PRO A 1 189 ? 4.444   27.055 24.284 1.000 25.562  0 170 PRO A CD    1 ? ? 
ATOM   1295 N N     . TRP A 1 190 ? 7.218   24.620 25.083 1.000 24.954  0 171 TRP A N     1 ? ? 
ATOM   1296 C CA    . TRP A 1 190 ? 8.228   23.829 25.755 1.000 23.352  0 171 TRP A CA    1 ? ? 
ATOM   1297 C C     . TRP A 1 190 ? 7.980   22.344 25.513 1.000 24.366  0 171 TRP A C     1 ? ? 
ATOM   1298 O O     . TRP A 1 190 ? 8.851   21.548 25.827 1.000 24.486  0 171 TRP A O     1 ? ? 
ATOM   1299 C CB    . TRP A 1 190 ? 8.186   24.094 27.256 1.000 20.975  0 171 TRP A CB    1 ? ? 
ATOM   1300 C CG    . TRP A 1 190 ? 8.547   25.470 27.716 1.000 19.506  0 171 TRP A CG    1 ? ? 
ATOM   1301 C CD1   . TRP A 1 190 ? 7.725   26.556 27.750 1.000 18.795  0 171 TRP A CD1   1 ? ? 
ATOM   1302 C CD2   . TRP A 1 190 ? 9.785   25.885 28.313 1.000 18.134  0 171 TRP A CD2   1 ? ? 
ATOM   1303 N NE1   . TRP A 1 190 ? 8.365   27.618 28.319 1.000 17.633  0 171 TRP A NE1   1 ? ? 
ATOM   1304 C CE2   . TRP A 1 190 ? 9.625   27.240 28.682 1.000 17.730  0 171 TRP A CE2   1 ? ? 
ATOM   1305 C CE3   . TRP A 1 190 ? 11.011  25.259 28.563 1.000 17.572  0 171 TRP A CE3   1 ? ? 
ATOM   1306 C CZ2   . TRP A 1 190 ? 10.656  27.994 29.240 1.000 18.181  0 171 TRP A CZ2   1 ? ? 
ATOM   1307 C CZ3   . TRP A 1 190 ? 12.030  26.000 29.136 1.000 18.033  0 171 TRP A CZ3   1 ? ? 
ATOM   1308 C CH2   . TRP A 1 190 ? 11.857  27.351 29.457 1.000 18.207  0 171 TRP A CH2   1 ? ? 
ATOM   1309 N N     . LEU A 1 191 ? 6.797   21.976 25.001 1.000 26.730  0 172 LEU A N     1 ? ? 
ATOM   1310 C CA    . LEU A 1 191 ? 6.417   20.578 24.835 1.000 29.181  0 172 LEU A CA    1 ? ? 
ATOM   1311 C C     . LEU A 1 191 ? 6.725   20.118 23.408 1.000 32.834  0 172 LEU A C     1 ? ? 
ATOM   1312 O O     . LEU A 1 191 ? 6.153   20.639 22.446 1.000 32.866  0 172 LEU A O     1 ? ? 
ATOM   1313 C CB    . LEU A 1 191 ? 4.919   20.430 25.098 1.000 26.713  0 172 LEU A CB    1 ? ? 
ATOM   1314 C CG    . LEU A 1 191 ? 4.438   20.862 26.470 1.000 25.655  0 172 LEU A CG    1 ? ? 
ATOM   1315 C CD1   . LEU A 1 191 ? 3.022   20.364 26.671 1.000 26.223  0 172 LEU A CD1   1 ? ? 
ATOM   1316 C CD2   . LEU A 1 191 ? 5.328   20.273 27.553 1.000 25.985  0 172 LEU A CD2   1 ? ? 
ATOM   1317 N N     . LYS A 1 192 ? 7.591   19.107 23.294 1.000 35.068  0 173 LYS A N     1 ? ? 
ATOM   1318 C CA    . LYS A 1 192 ? 7.948   18.535 22.009 1.000 38.357  0 173 LYS A CA    1 ? ? 
ATOM   1319 C C     . LYS A 1 192 ? 8.416   17.115 22.264 1.000 36.348  0 173 LYS A C     1 ? ? 
ATOM   1320 O O     . LYS A 1 192 ? 9.606   16.851 22.417 1.000 36.894  0 173 LYS A O     1 ? ? 
ATOM   1321 C CB    . LYS A 1 192 ? 9.000   19.329 21.217 1.000 41.764  0 173 LYS A CB    1 ? ? 
ATOM   1322 C CG    . LYS A 1 192 ? 9.893   20.336 21.933 1.000 47.768  0 173 LYS A CG    1 ? ? 
ATOM   1323 C CD    . LYS A 1 192 ? 11.008  19.627 22.704 1.000 49.095  0 173 LYS A CD    1 ? ? 
ATOM   1324 C CE    . LYS A 1 192 ? 11.970  20.542 23.429 1.000 48.106  0 173 LYS A CE    1 ? ? 
ATOM   1325 N NZ    . LYS A 1 192 ? 12.987  19.724 24.112 1.000 47.554  0 173 LYS A NZ    1 ? ? 
ATOM   1326 N N     . ASN A 1 193 ? 7.435   16.207 22.302 1.000 36.729  0 174 ASN A N     1 ? ? 
ATOM   1327 C CA    . ASN A 1 193 ? 7.679   14.789 22.520 1.000 37.676  0 174 ASN A CA    1 ? ? 
ATOM   1328 C C     . ASN A 1 193 ? 8.624   14.613 23.704 1.000 35.937  0 174 ASN A C     1 ? ? 
ATOM   1329 O O     . ASN A 1 193 ? 9.653   13.945 23.605 1.000 35.323  0 174 ASN A O     1 ? ? 
ATOM   1330 C CB    . ASN A 1 193 ? 8.185   14.075 21.263 1.000 40.364  0 174 ASN A CB    1 ? ? 
ATOM   1331 C CG    . ASN A 1 193 ? 7.175   14.115 20.138 1.000 45.884  0 174 ASN A CG    1 ? ? 
ATOM   1332 O OD1   . ASN A 1 193 ? 7.213   15.003 19.286 1.000 48.167  0 174 ASN A OD1   1 ? ? 
ATOM   1333 N ND2   . ASN A 1 193 ? 6.258   13.162 20.135 1.000 46.642  0 174 ASN A ND2   1 ? ? 
ATOM   1334 N N     . ASN A 1 194 ? 8.257   15.241 24.827 1.000 33.082  0 175 ASN A N     1 ? ? 
ATOM   1335 C CA    . ASN A 1 194 ? 9.032   15.101 26.047 1.000 30.620  0 175 ASN A CA    1 ? ? 
ATOM   1336 C C     . ASN A 1 194 ? 8.114   14.672 27.195 1.000 27.797  0 175 ASN A C     1 ? ? 
ATOM   1337 O O     . ASN A 1 194 ? 6.886   14.679 27.087 1.000 30.054  0 175 ASN A O     1 ? ? 
ATOM   1338 C CB    . ASN A 1 194 ? 9.913   16.325 26.290 1.000 30.077  0 175 ASN A CB    1 ? ? 
ATOM   1339 C CG    . ASN A 1 194 ? 9.197   17.643 26.141 1.000 30.579  0 175 ASN A CG    1 ? ? 
ATOM   1340 O OD1   . ASN A 1 194 ? 7.980   17.678 25.948 1.000 30.069  0 175 ASN A OD1   1 ? ? 
ATOM   1341 N ND2   . ASN A 1 194 ? 9.967   18.724 26.206 1.000 30.567  0 175 ASN A ND2   1 ? ? 
ATOM   1342 N N     . GLN A 1 195 ? 8.723   14.239 28.293 1.000 24.177  0 176 GLN A N     1 ? ? 
ATOM   1343 C CA    . GLN A 1 195 ? 7.972   13.974 29.507 1.000 22.809  0 176 GLN A CA    1 ? ? 
ATOM   1344 C C     . GLN A 1 195 ? 7.484   15.287 30.113 1.000 22.233  0 176 GLN A C     1 ? ? 
ATOM   1345 O O     . GLN A 1 195 ? 8.150   16.311 29.988 1.000 23.301  0 176 GLN A O     1 ? ? 
ATOM   1346 C CB    . GLN A 1 195 ? 8.871   13.246 30.495 1.000 21.410  0 176 GLN A CB    1 ? ? 
ATOM   1347 C CG    . GLN A 1 195 ? 9.184   11.830 30.057 1.000 22.158  0 176 GLN A CG    1 ? ? 
ATOM   1348 C CD    . GLN A 1 195 ? 7.972   10.945 30.156 1.000 23.641  0 176 GLN A CD    1 ? ? 
ATOM   1349 O OE1   . GLN A 1 195 ? 7.446   10.718 31.240 1.000 26.249  0 176 GLN A OE1   1 ? ? 
ATOM   1350 N NE2   . GLN A 1 195 ? 7.565   10.437 29.006 1.000 23.135  0 176 GLN A NE2   1 ? ? 
ATOM   1351 N N     . PHE A 1 196 ? 6.311   15.255 30.747 1.000 20.608  0 177 PHE A N     1 ? ? 
ATOM   1352 C CA    . PHE A 1 196 ? 5.836   16.473 31.376 1.000 20.490  0 177 PHE A CA    1 ? ? 
ATOM   1353 C C     . PHE A 1 196 ? 4.909   16.217 32.557 1.000 19.556  0 177 PHE A C     1 ? ? 
ATOM   1354 O O     . PHE A 1 196 ? 4.309   15.156 32.706 1.000 21.447  0 177 PHE A O     1 ? ? 
ATOM   1355 C CB    . PHE A 1 196 ? 5.198   17.421 30.359 1.000 20.398  0 177 PHE A CB    1 ? ? 
ATOM   1356 C CG    . PHE A 1 196 ? 4.045   16.861 29.570 1.000 19.776  0 177 PHE A CG    1 ? ? 
ATOM   1357 C CD1   . PHE A 1 196 ? 2.774   16.793 30.119 1.000 19.295  0 177 PHE A CD1   1 ? ? 
ATOM   1358 C CD2   . PHE A 1 196 ? 4.224   16.458 28.253 1.000 20.032  0 177 PHE A CD2   1 ? ? 
ATOM   1359 C CE1   . PHE A 1 196 ? 1.705   16.315 29.378 1.000 20.024  0 177 PHE A CE1   1 ? ? 
ATOM   1360 C CE2   . PHE A 1 196 ? 3.158   15.963 27.512 1.000 19.452  0 177 PHE A CE2   1 ? ? 
ATOM   1361 C CZ    . PHE A 1 196 ? 1.905   15.899 28.075 1.000 20.117  0 177 PHE A CZ    1 ? ? 
ATOM   1362 N N     . CYS A 1 197 ? 4.787   17.250 33.384 1.000 17.975  0 178 CYS A N     1 ? ? 
ATOM   1363 C CA    . CYS A 1 197 ? 3.873   17.270 34.508 1.000 16.985  0 178 CYS A CA    1 ? ? 
ATOM   1364 C C     . CYS A 1 197 ? 3.566   18.733 34.816 1.000 16.547  0 178 CYS A C     1 ? ? 
ATOM   1365 O O     . CYS A 1 197 ? 4.439   19.464 35.272 1.000 15.449  0 178 CYS A O     1 ? ? 
ATOM   1366 C CB    . CYS A 1 197 ? 4.521   16.589 35.703 1.000 16.739  0 178 CYS A CB    1 ? ? 
ATOM   1367 S SG    . CYS A 1 197 ? 3.482   16.577 37.178 1.000 17.074  0 178 CYS A SG    1 ? ? 
ATOM   1368 N N     . ILE A 1 198 ? 2.326   19.149 34.532 1.000 16.453  0 179 ILE A N     1 ? ? 
ATOM   1369 C CA    . ILE A 1 198 ? 1.917   20.543 34.537 1.000 16.056  0 179 ILE A CA    1 ? ? 
ATOM   1370 C C     . ILE A 1 198 ? 0.681   20.689 35.416 1.000 16.119  0 179 ILE A C     1 ? ? 
ATOM   1371 O O     . ILE A 1 198 ? -0.308  19.987 35.237 1.000 17.076  0 179 ILE A O     1 ? ? 
ATOM   1372 C CB    . ILE A 1 198 ? 1.667   21.030 33.091 1.000 16.190  0 179 ILE A CB    1 ? ? 
ATOM   1373 C CG1   . ILE A 1 198 ? 2.968   21.006 32.280 1.000 15.430  0 179 ILE A CG1   1 ? ? 
ATOM   1374 C CG2   . ILE A 1 198 ? 1.009   22.407 33.062 1.000 15.599  0 179 ILE A CG2   1 ? ? 
ATOM   1375 C CD1   . ILE A 1 198 ? 2.794   20.706 30.826 1.000 15.159  0 179 ILE A CD1   1 ? ? 
ATOM   1376 N N     . LYS A 1 199 ? 0.751   21.625 36.360 1.000 16.316  0 180 LYS A N     1 ? ? 
ATOM   1377 C CA    . LYS A 1 199 ? -0.395  21.921 37.197 1.000 16.150  0 180 LYS A CA    1 ? ? 
ATOM   1378 C C     . LYS A 1 199 ? -1.464  22.626 36.382 1.000 16.261  0 180 LYS A C     1 ? ? 
ATOM   1379 O O     . LYS A 1 199 ? -1.194  23.565 35.633 1.000 17.681  0 180 LYS A O     1 ? ? 
ATOM   1380 C CB    . LYS A 1 199 ? -0.008  22.800 38.378 1.000 16.441  0 180 LYS A CB    1 ? ? 
ATOM   1381 C CG    . LYS A 1 199 ? -1.131  22.957 39.377 1.000 16.798  0 180 LYS A CG    1 ? ? 
ATOM   1382 C CD    . LYS A 1 199 ? -0.642  23.484 40.676 1.000 18.002  0 180 LYS A CD    1 ? ? 
ATOM   1383 C CE    . LYS A 1 199 ? -0.777  24.979 40.801 1.000 18.341  0 180 LYS A CE    1 ? ? 
ATOM   1384 N NZ    . LYS A 1 199 ? -0.577  25.339 42.227 1.000 18.121  0 180 LYS A NZ    1 ? ? 
ATOM   1385 N N     . VAL A 1 200 ? -2.693  22.152 36.560 1.000 16.766  0 181 VAL A N     1 ? ? 
ATOM   1386 C CA    . VAL A 1 200 ? -3.853  22.827 36.016 1.000 17.000  0 181 VAL A CA    1 ? ? 
ATOM   1387 C C     . VAL A 1 200 ? -4.692  23.323 37.189 1.000 17.886  0 181 VAL A C     1 ? ? 
ATOM   1388 O O     . VAL A 1 200 ? -5.441  22.552 37.780 1.000 18.601  0 181 VAL A O     1 ? ? 
ATOM   1389 C CB    . VAL A 1 200 ? -4.648  21.900 35.092 1.000 15.909  0 181 VAL A CB    1 ? ? 
ATOM   1390 C CG1   . VAL A 1 200 ? -5.781  22.652 34.428 1.000 15.907  0 181 VAL A CG1   1 ? ? 
ATOM   1391 C CG2   . VAL A 1 200 ? -3.727  21.297 34.055 1.000 16.369  0 181 VAL A CG2   1 ? ? 
ATOM   1392 N N     . LEU A 1 201 ? -4.580  24.620 37.495 1.000 18.971  0 182 LEU A N     1 ? ? 
ATOM   1393 C CA    . LEU A 1 201 ? -5.081  25.146 38.751 1.000 19.801  0 182 LEU A CA    1 ? ? 
ATOM   1394 C C     . LEU A 1 201 ? -6.595  25.021 38.807 1.000 20.882  0 182 LEU A C     1 ? ? 
ATOM   1395 O O     . LEU A 1 201 ? -7.134  24.601 39.828 1.000 22.675  0 182 LEU A O     1 ? ? 
ATOM   1396 C CB    . LEU A 1 201 ? -4.669  26.610 38.863 1.000 20.098  0 182 LEU A CB    1 ? ? 
ATOM   1397 C CG    . LEU A 1 201 ? -5.445  27.414 39.900 1.000 20.118  0 182 LEU A CG    1 ? ? 
ATOM   1398 C CD1   . LEU A 1 201 ? -4.896  27.182 41.304 1.000 18.569  0 182 LEU A CD1   1 ? ? 
ATOM   1399 C CD2   . LEU A 1 201 ? -5.468  28.890 39.500 1.000 21.441  0 182 LEU A CD2   1 ? ? 
ATOM   1400 N N     . ASN A 1 202 ? -7.258  25.425 37.715 1.000 21.948  0 183 ASN A N     1 ? ? 
ATOM   1401 C CA    . ASN A 1 202 ? -8.705  25.356 37.576 1.000 22.218  0 183 ASN A CA    1 ? ? 
ATOM   1402 C C     . ASN A 1 202 ? -9.036  24.567 36.314 1.000 23.348  0 183 ASN A C     1 ? ? 
ATOM   1403 O O     . ASN A 1 202 ? -9.027  25.116 35.213 1.000 22.362  0 183 ASN A O     1 ? ? 
ATOM   1404 C CB    . ASN A 1 202 ? -9.353  26.742 37.521 1.000 22.394  0 183 ASN A CB    1 ? ? 
ATOM   1405 C CG    . ASN A 1 202 ? -10.868 26.676 37.570 1.000 21.581  0 183 ASN A CG    1 ? ? 
ATOM   1406 O OD1   . ASN A 1 202 ? -11.476 25.850 36.888 1.000 22.140  0 183 ASN A OD1   1 ? ? 
ATOM   1407 N ND2   . ASN A 1 202 ? -11.479 27.514 38.388 1.000 20.973  0 183 ASN A ND2   1 ? ? 
ATOM   1408 N N     . PRO A 1 203 ? -9.310  23.249 36.430 1.000 25.137  0 184 PRO A N     1 ? ? 
ATOM   1409 C CA    . PRO A 1 203 ? -9.610  22.435 35.254 1.000 24.090  0 184 PRO A CA    1 ? ? 
ATOM   1410 C C     . PRO A 1 203 ? -11.093 22.287 34.919 1.000 24.115  0 184 PRO A C     1 ? ? 
ATOM   1411 O O     . PRO A 1 203 ? -11.424 21.628 33.943 1.000 25.603  0 184 PRO A O     1 ? ? 
ATOM   1412 C CB    . PRO A 1 203 ? -9.002  21.095 35.663 1.000 23.384  0 184 PRO A CB    1 ? ? 
ATOM   1413 C CG    . PRO A 1 203 ? -9.266  21.018 37.164 1.000 23.782  0 184 PRO A CG    1 ? ? 
ATOM   1414 C CD    . PRO A 1 203 ? -9.263  22.446 37.672 1.000 24.458  0 184 PRO A CD    1 ? ? 
ATOM   1415 N N     . TYR A 1 204 ? -11.984 22.927 35.684 1.000 23.943  0 185 TYR A N     1 ? ? 
ATOM   1416 C CA    . TYR A 1 204 ? -13.400 22.637 35.530 1.000 24.105  0 185 TYR A CA    1 ? ? 
ATOM   1417 C C     . TYR A 1 204 ? -14.134 23.698 34.716 1.000 24.514  0 185 TYR A C     1 ? ? 
ATOM   1418 O O     . TYR A 1 204 ? -15.272 23.456 34.330 1.000 25.432  0 185 TYR A O     1 ? ? 
ATOM   1419 C CB    . TYR A 1 204 ? -14.094 22.450 36.886 1.000 23.256  0 185 TYR A CB    1 ? ? 
ATOM   1420 C CG    . TYR A 1 204 ? -13.914 23.581 37.866 1.000 23.708  0 185 TYR A CG    1 ? ? 
ATOM   1421 C CD1   . TYR A 1 204 ? -14.665 24.745 37.763 1.000 24.237  0 185 TYR A CD1   1 ? ? 
ATOM   1422 C CD2   . TYR A 1 204 ? -12.968 23.489 38.882 1.000 24.017  0 185 TYR A CD2   1 ? ? 
ATOM   1423 C CE1   . TYR A 1 204 ? -14.460 25.801 38.635 1.000 24.821  0 185 TYR A CE1   1 ? ? 
ATOM   1424 C CE2   . TYR A 1 204 ? -12.785 24.527 39.783 1.000 24.756  0 185 TYR A CE2   1 ? ? 
ATOM   1425 C CZ    . TYR A 1 204 ? -13.543 25.679 39.666 1.000 24.904  0 185 TYR A CZ    1 ? ? 
ATOM   1426 O OH    . TYR A 1 204 ? -13.344 26.710 40.538 1.000 24.048  0 185 TYR A OH    1 ? ? 
ATOM   1427 N N     . MET A 1 205 ? -13.520 24.866 34.499 1.000 24.892  0 186 MET A N     1 ? ? 
ATOM   1428 C CA    . MET A 1 205 ? -14.160 25.906 33.711 1.000 26.684  0 186 MET A CA    1 ? ? 
ATOM   1429 C C     . MET A 1 205 ? -14.160 25.498 32.238 1.000 29.257  0 186 MET A C     1 ? ? 
ATOM   1430 O O     . MET A 1 205 ? -13.155 25.003 31.711 1.000 29.379  0 186 MET A O     1 ? ? 
ATOM   1431 C CB    . MET A 1 205 ? -13.448 27.248 33.869 1.000 25.038  0 186 MET A CB    1 ? ? 
ATOM   1432 C CG    . MET A 1 205 ? -13.454 27.797 35.282 1.000 25.080  0 186 MET A CG    1 ? ? 
ATOM   1433 S SD    . MET A 1 205 ? -15.060 28.140 35.990 1.000 24.075  0 186 MET A SD    1 ? ? 
ATOM   1434 C CE    . MET A 1 205 ? -15.430 29.653 35.110 1.000 23.861  0 186 MET A CE    1 ? ? 
ATOM   1435 N N     . PRO A 1 206 ? -15.281 25.711 31.518 1.000 32.749  0 187 PRO A N     1 ? ? 
ATOM   1436 C CA    . PRO A 1 206 ? -15.420 25.209 30.151 1.000 35.743  0 187 PRO A CA    1 ? ? 
ATOM   1437 C C     . PRO A 1 206 ? -14.308 25.592 29.178 1.000 34.464  0 187 PRO A C     1 ? ? 
ATOM   1438 O O     . PRO A 1 206 ? -13.929 24.786 28.337 1.000 30.937  0 187 PRO A O     1 ? ? 
ATOM   1439 C CB    . PRO A 1 206 ? -16.758 25.816 29.703 1.000 37.967  0 187 PRO A CB    1 ? ? 
ATOM   1440 C CG    . PRO A 1 206 ? -17.532 25.984 31.003 1.000 38.869  0 187 PRO A CG    1 ? ? 
ATOM   1441 C CD    . PRO A 1 206 ? -16.475 26.446 31.979 1.000 35.874  0 187 PRO A CD    1 ? ? 
ATOM   1442 N N     . THR A 1 207 ? -13.797 26.822 29.272 1.000 37.386  0 188 THR A N     1 ? ? 
ATOM   1443 C CA    . THR A 1 207 ? -12.777 27.261 28.329 1.000 39.207  0 188 THR A CA    1 ? ? 
ATOM   1444 C C     . THR A 1 207 ? -11.474 26.498 28.559 1.000 37.477  0 188 THR A C     1 ? ? 
ATOM   1445 O O     . THR A 1 207 ? -10.758 26.170 27.603 1.000 40.328  0 188 THR A O     1 ? ? 
ATOM   1446 C CB    . THR A 1 207 ? -12.433 28.750 28.488 1.000 42.592  0 188 THR A CB    1 ? ? 
ATOM   1447 O OG1   . THR A 1 207 ? -13.544 29.581 28.840 1.000 43.965  0 188 THR A OG1   1 ? ? 
ATOM   1448 C CG2   . THR A 1 207 ? -11.651 29.335 27.331 1.000 47.077  0 188 THR A CG2   1 ? ? 
ATOM   1449 N N     . VAL A 1 208 ? -11.165 26.216 29.829 1.000 33.021  0 189 VAL A N     1 ? ? 
ATOM   1450 C CA    . VAL A 1 208 ? -9.969  25.454 30.145 1.000 31.130  0 189 VAL A CA    1 ? ? 
ATOM   1451 C C     . VAL A 1 208 ? -10.062 24.044 29.562 1.000 31.090  0 189 VAL A C     1 ? ? 
ATOM   1452 O O     . VAL A 1 208 ? -9.141  23.599 28.870 1.000 27.518  0 189 VAL A O     1 ? ? 
ATOM   1453 C CB    . VAL A 1 208 ? -9.732  25.434 31.660 1.000 30.458  0 189 VAL A CB    1 ? ? 
ATOM   1454 C CG1   . VAL A 1 208 ? -8.555  24.541 31.998 1.000 30.453  0 189 VAL A CG1   1 ? ? 
ATOM   1455 C CG2   . VAL A 1 208 ? -9.514  26.845 32.187 1.000 30.155  0 189 VAL A CG2   1 ? ? 
ATOM   1456 N N     . ILE A 1 209 ? -11.192 23.374 29.838 1.000 31.832  0 190 ILE A N     1 ? ? 
ATOM   1457 C CA    . ILE A 1 209 ? -11.507 22.054 29.311 1.000 32.226  0 190 ILE A CA    1 ? ? 
ATOM   1458 C C     . ILE A 1 209 ? -11.252 22.000 27.800 1.000 32.460  0 190 ILE A C     1 ? ? 
ATOM   1459 O O     . ILE A 1 209 ? -10.673 21.040 27.295 1.000 32.052  0 190 ILE A O     1 ? ? 
ATOM   1460 C CB    . ILE A 1 209 ? -12.971 21.701 29.648 1.000 32.981  0 190 ILE A CB    1 ? ? 
ATOM   1461 C CG1   . ILE A 1 209 ? -13.176 21.456 31.142 1.000 30.248  0 190 ILE A CG1   1 ? ? 
ATOM   1462 C CG2   . ILE A 1 209 ? -13.461 20.524 28.810 1.000 32.848  0 190 ILE A CG2   1 ? ? 
ATOM   1463 C CD1   . ILE A 1 209 ? -13.015 20.020 31.539 1.000 29.403  0 190 ILE A CD1   1 ? ? 
ATOM   1464 N N     . GLU A 1 210 ? -11.719 23.026 27.085 1.000 33.283  0 191 GLU A N     1 ? ? 
ATOM   1465 C CA    . GLU A 1 210 ? -11.530 23.122 25.648 1.000 35.487  0 191 GLU A CA    1 ? ? 
ATOM   1466 C C     . GLU A 1 210 ? -10.035 23.135 25.323 1.000 35.017  0 191 GLU A C     1 ? ? 
ATOM   1467 O O     . GLU A 1 210 ? -9.577  22.372 24.467 1.000 33.812  0 191 GLU A O     1 ? ? 
ATOM   1468 C CB    . GLU A 1 210 ? -12.299 24.322 25.100 1.000 35.263  0 191 GLU A CB    1 ? ? 
ATOM   1469 C CG    . GLU A 1 210 ? -12.270 24.423 23.585 1.000 37.033  0 191 GLU A CG    1 ? ? 
ATOM   1470 C CD    . GLU A 1 210 ? -13.071 25.610 23.083 1.000 38.318  0 191 GLU A CD    1 ? ? 
ATOM   1471 O OE1   . GLU A 1 210 ? -13.402 26.477 23.936 1.000 37.960  0 191 GLU A OE1   1 ? ? 
ATOM   1472 O OE2   . GLU A 1 210 ? -13.362 25.671 21.871 1.000 41.735  0 191 GLU A OE2   1 ? ? 
ATOM   1473 N N     . HIS A 1 211 ? -9.273  23.966 26.038 1.000 34.151  0 192 HIS A N     1 ? ? 
ATOM   1474 C CA    . HIS A 1 211 ? -7.849  24.037 25.769 1.000 35.902  0 192 HIS A CA    1 ? ? 
ATOM   1475 C C     . HIS A 1 211 ? -7.170  22.701 26.047 1.000 35.924  0 192 HIS A C     1 ? ? 
ATOM   1476 O O     . HIS A 1 211 ? -6.296  22.287 25.289 1.000 35.347  0 192 HIS A O     1 ? ? 
ATOM   1477 C CB    . HIS A 1 211 ? -7.200  25.121 26.619 1.000 39.389  0 192 HIS A CB    1 ? ? 
ATOM   1478 C CG    . HIS A 1 211 ? -7.310  26.480 26.023 1.000 43.621  0 192 HIS A CG    1 ? ? 
ATOM   1479 N ND1   . HIS A 1 211 ? -6.471  26.922 25.030 1.000 45.218  0 192 HIS A ND1   1 ? ? 
ATOM   1480 C CD2   . HIS A 1 211 ? -8.164  27.491 26.267 1.000 44.772  0 192 HIS A CD2   1 ? ? 
ATOM   1481 C CE1   . HIS A 1 211 ? -6.815  28.145 24.688 1.000 44.547  0 192 HIS A CE1   1 ? ? 
ATOM   1482 N NE2   . HIS A 1 211 ? -7.822  28.541 25.470 1.000 43.420  0 192 HIS A NE2   1 ? ? 
ATOM   1483 N N     . LEU A 1 212 ? -7.546  22.064 27.170 1.000 33.181  0 193 LEU A N     1 ? ? 
ATOM   1484 C CA    . LEU A 1 212 ? -6.923  20.811 27.572 1.000 31.236  0 193 LEU A CA    1 ? ? 
ATOM   1485 C C     . LEU A 1 212 ? -7.187  19.722 26.531 1.000 32.674  0 193 LEU A C     1 ? ? 
ATOM   1486 O O     . LEU A 1 212 ? -6.313  18.891 26.235 1.000 30.563  0 193 LEU A O     1 ? ? 
ATOM   1487 C CB    . LEU A 1 212 ? -7.473  20.396 28.938 1.000 29.504  0 193 LEU A CB    1 ? ? 
ATOM   1488 C CG    . LEU A 1 212 ? -6.848  21.122 30.121 1.000 29.718  0 193 LEU A CG    1 ? ? 
ATOM   1489 C CD1   . LEU A 1 212 ? -7.591  20.808 31.402 1.000 29.236  0 193 LEU A CD1   1 ? ? 
ATOM   1490 C CD2   . LEU A 1 212 ? -5.373  20.771 30.242 1.000 29.477  0 193 LEU A CD2   1 ? ? 
ATOM   1491 N N     . GLU A 1 213 ? -8.405  19.742 25.986 1.000 34.798  0 194 GLU A N     1 ? ? 
ATOM   1492 C CA    . GLU A 1 213 ? -8.783  18.763 24.988 1.000 37.202  0 194 GLU A CA    1 ? ? 
ATOM   1493 C C     . GLU A 1 213 ? -7.889  18.901 23.752 1.000 36.755  0 194 GLU A C     1 ? ? 
ATOM   1494 O O     . GLU A 1 213 ? -7.338  17.908 23.269 1.000 35.572  0 194 GLU A O     1 ? ? 
ATOM   1495 C CB    . GLU A 1 213 ? -10.273 18.878 24.677 1.000 39.680  0 194 GLU A CB    1 ? ? 
ATOM   1496 C CG    . GLU A 1 213 ? -11.116 18.034 25.613 1.000 44.311  0 194 GLU A CG    1 ? ? 
ATOM   1497 C CD    . GLU A 1 213 ? -12.616 18.283 25.706 1.000 49.714  0 194 GLU A CD    1 ? ? 
ATOM   1498 O OE1   . GLU A 1 213 ? -13.110 18.015 26.778 1.000 52.111  0 194 GLU A OE1   1 ? ? 
ATOM   1499 O OE2   . GLU A 1 213 ? -13.310 18.666 24.735 1.000 48.713  0 194 GLU A OE2   1 ? ? 
ATOM   1500 N N     . ARG A 1 214 ? -7.697  20.146 23.291 1.000 34.488  0 195 ARG A N     1 ? ? 
ATOM   1501 C CA    . ARG A 1 214 ? -6.757  20.434 22.212 1.000 35.157  0 195 ARG A CA    1 ? ? 
ATOM   1502 C C     . ARG A 1 214 ? -5.354  19.909 22.552 1.000 33.088  0 195 ARG A C     1 ? ? 
ATOM   1503 O O     . ARG A 1 214 ? -4.698  19.242 21.751 1.000 32.753  0 195 ARG A O     1 ? ? 
ATOM   1504 C CB    . ARG A 1 214 ? -6.706  21.940 21.949 1.000 36.663  0 195 ARG A CB    1 ? ? 
ATOM   1505 C CG    . ARG A 1 214 ? -6.052  22.298 20.628 1.000 38.629  0 195 ARG A CG    1 ? ? 
ATOM   1506 C CD    . ARG A 1 214 ? -5.950  23.799 20.504 1.000 39.636  0 195 ARG A CD    1 ? ? 
ATOM   1507 N NE    . ARG A 1 214 ? -5.723  24.383 21.803 1.000 39.775  0 195 ARG A NE    1 ? ? 
ATOM   1508 C CZ    . ARG A 1 214 ? -4.539  24.646 22.307 1.000 40.014  0 195 ARG A CZ    1 ? ? 
ATOM   1509 N NH1   . ARG A 1 214 ? -3.441  24.356 21.627 1.000 40.368  0 195 ARG A NH1   1 ? ? 
ATOM   1510 N NH2   . ARG A 1 214 ? -4.489  25.186 23.512 1.000 42.657  0 195 ARG A NH2   1 ? ? 
ATOM   1511 N N     . LEU A 1 215 ? -4.901  20.199 23.768 1.000 31.746  0 196 LEU A N     1 ? ? 
ATOM   1512 C CA    . LEU A 1 215 ? -3.525  19.903 24.111 1.000 31.719  0 196 LEU A CA    1 ? ? 
ATOM   1513 C C     . LEU A 1 215 ? -3.301  18.389 24.170 1.000 32.296  0 196 LEU A C     1 ? ? 
ATOM   1514 O O     . LEU A 1 215 ? -2.239  17.904 23.755 1.000 31.511  0 196 LEU A O     1 ? ? 
ATOM   1515 C CB    . LEU A 1 215 ? -3.196  20.593 25.437 1.000 31.204  0 196 LEU A CB    1 ? ? 
ATOM   1516 C CG    . LEU A 1 215 ? -2.965  22.097 25.316 1.000 31.667  0 196 LEU A CG    1 ? ? 
ATOM   1517 C CD1   . LEU A 1 215 ? -3.046  22.771 26.668 1.000 31.378  0 196 LEU A CD1   1 ? ? 
ATOM   1518 C CD2   . LEU A 1 215 ? -1.630  22.414 24.649 1.000 29.127  0 196 LEU A CD2   1 ? ? 
ATOM   1519 N N     . GLN A 1 216 ? -4.287  17.658 24.712 1.000 30.917  0 197 GLN A N     1 ? ? 
ATOM   1520 C CA    . GLN A 1 216 ? -4.223  16.208 24.823 1.000 29.834  0 197 GLN A CA    1 ? ? 
ATOM   1521 C C     . GLN A 1 216 ? -4.158  15.585 23.427 1.000 28.927  0 197 GLN A C     1 ? ? 
ATOM   1522 O O     . GLN A 1 216 ? -3.363  14.678 23.192 1.000 27.089  0 197 GLN A O     1 ? ? 
ATOM   1523 C CB    . GLN A 1 216 ? -5.441  15.687 25.595 1.000 28.562  0 197 GLN A CB    1 ? ? 
ATOM   1524 C CG    . GLN A 1 216 ? -5.400  14.210 25.949 1.000 28.409  0 197 GLN A CG    1 ? ? 
ATOM   1525 C CD    . GLN A 1 216 ? -6.717  13.688 26.488 1.000 29.235  0 197 GLN A CD    1 ? ? 
ATOM   1526 O OE1   . GLN A 1 216 ? -7.792  14.096 26.048 1.000 28.287  0 197 GLN A OE1   1 ? ? 
ATOM   1527 N NE2   . GLN A 1 216 ? -6.649  12.753 27.430 1.000 27.951  0 197 GLN A NE2   1 ? ? 
ATOM   1528 N N     . ARG A 1 217 ? -4.976  16.088 22.490 1.000 30.100  0 198 ARG A N     1 ? ? 
ATOM   1529 C CA    . ARG A 1 217 ? -4.977  15.598 21.116 1.000 31.925  0 198 ARG A CA    1 ? ? 
ATOM   1530 C C     . ARG A 1 217 ? -3.604  15.758 20.467 1.000 32.965  0 198 ARG A C     1 ? ? 
ATOM   1531 O O     . ARG A 1 217 ? -3.168  14.903 19.702 1.000 34.886  0 198 ARG A O     1 ? ? 
ATOM   1532 C CB    . ARG A 1 217 ? -6.003  16.356 20.270 1.000 31.884  0 198 ARG A CB    1 ? ? 
ATOM   1533 C CG    . ARG A 1 217 ? -7.431  15.888 20.478 1.000 33.126  0 198 ARG A CG    1 ? ? 
ATOM   1534 C CD    . ARG A 1 217 ? -8.367  16.432 19.414 1.000 35.246  0 198 ARG A CD    1 ? ? 
ATOM   1535 N NE    . ARG A 1 217 ? -8.438  17.886 19.344 1.000 38.463  0 198 ARG A NE    1 ? ? 
ATOM   1536 C CZ    . ARG A 1 217 ? -9.241  18.654 20.080 1.000 40.404  0 198 ARG A CZ    1 ? ? 
ATOM   1537 N NH1   . ARG A 1 217 ? -10.055 18.109 20.970 1.000 42.258  0 198 ARG A NH1   1 ? ? 
ATOM   1538 N NH2   . ARG A 1 217 ? -9.219  19.971 19.932 1.000 39.888  0 198 ARG A NH2   1 ? ? 
ATOM   1539 N N     . LYS A 1 218 ? -2.918  16.856 20.785 1.000 34.727  0 199 LYS A N     1 ? ? 
ATOM   1540 C CA    . LYS A 1 218 ? -1.626  17.115 20.180 1.000 34.082  0 199 LYS A CA    1 ? ? 
ATOM   1541 C C     . LYS A 1 218 ? -0.532  16.360 20.926 1.000 32.324  0 199 LYS A C     1 ? ? 
ATOM   1542 O O     . LYS A 1 218 ? 0.299   15.717 20.293 1.000 33.792  0 199 LYS A O     1 ? ? 
ATOM   1543 C CB    . LYS A 1 218 ? -1.355  18.617 20.182 1.000 37.652  0 199 LYS A CB    1 ? ? 
ATOM   1544 C CG    . LYS A 1 218 ? -0.189  19.087 19.332 1.000 42.302  0 199 LYS A CG    1 ? ? 
ATOM   1545 C CD    . LYS A 1 218 ? -0.295  20.562 19.056 1.000 47.693  0 199 LYS A CD    1 ? ? 
ATOM   1546 C CE    . LYS A 1 218 ? -1.677  20.959 18.557 1.000 49.781  0 199 LYS A CE    1 ? ? 
ATOM   1547 N NZ    . LYS A 1 218 ? -1.733  22.303 17.932 1.000 46.281  0 199 LYS A NZ    1 ? ? 
ATOM   1548 N N     . HIS A 1 219 ? -0.553  16.412 22.266 1.000 30.678  0 200 HIS A N     1 ? ? 
ATOM   1549 C CA    . HIS A 1 219 ? 0.594   15.986 23.047 1.000 27.941  0 200 HIS A CA    1 ? ? 
ATOM   1550 C C     . HIS A 1 219 ? 0.310   14.769 23.928 1.000 28.002  0 200 HIS A C     1 ? ? 
ATOM   1551 O O     . HIS A 1 219 ? 1.224   14.292 24.618 1.000 27.954  0 200 HIS A O     1 ? ? 
ATOM   1552 C CB    . HIS A 1 219 ? 1.107   17.129 23.919 1.000 30.590  0 200 HIS A CB    1 ? ? 
ATOM   1553 C CG    . HIS A 1 219 ? 1.706   18.249 23.155 1.000 33.642  0 200 HIS A CG    1 ? ? 
ATOM   1554 N ND1   . HIS A 1 219 ? 1.203   19.505 23.127 1.000 35.153  0 200 HIS A ND1   1 ? ? 
ATOM   1555 C CD2   . HIS A 1 219 ? 2.801   18.297 22.397 1.000 33.986  0 200 HIS A CD2   1 ? ? 
ATOM   1556 C CE1   . HIS A 1 219 ? 1.990   20.259 22.396 1.000 32.916  0 200 HIS A CE1   1 ? ? 
ATOM   1557 N NE2   . HIS A 1 219 ? 2.929   19.565 21.940 1.000 31.796  0 200 HIS A NE2   1 ? ? 
ATOM   1558 N N     . GLY A 1 220 ? -0.940  14.281 23.931 1.000 25.155  0 201 GLY A N     1 ? ? 
ATOM   1559 C CA    . GLY A 1 220 ? -1.307  13.107 24.708 1.000 23.463  0 201 GLY A CA    1 ? ? 
ATOM   1560 C C     . GLY A 1 220 ? -1.462  13.421 26.197 1.000 22.969  0 201 GLY A C     1 ? ? 
ATOM   1561 O O     . GLY A 1 220 ? -1.790  14.539 26.597 1.000 22.325  0 201 GLY A O     1 ? ? 
ATOM   1562 N N     . GLY A 1 221 ? -1.183  12.420 27.019 1.000 22.183  0 202 GLY A N     1 ? ? 
ATOM   1563 C CA    . GLY A 1 221 ? -1.307  12.601 28.451 1.000 23.959  0 202 GLY A CA    1 ? ? 
ATOM   1564 C C     . GLY A 1 221 ? -2.750  12.593 28.961 1.000 24.307  0 202 GLY A C     1 ? ? 
ATOM   1565 O O     . GLY A 1 221 ? -3.702  12.333 28.228 1.000 24.234  0 202 GLY A O     1 ? ? 
ATOM   1566 N N     . MET A 1 222 ? -2.860  12.844 30.268 1.000 24.660  0 203 MET A N     1 ? ? 
ATOM   1567 C CA    . MET A 1 222 ? -4.072  12.706 31.058 1.000 25.513  0 203 MET A CA    1 ? ? 
ATOM   1568 C C     . MET A 1 222 ? -3.975  13.656 32.252 1.000 24.262  0 203 MET A C     1 ? ? 
ATOM   1569 O O     . MET A 1 222 ? -2.879  13.993 32.690 1.000 21.966  0 203 MET A O     1 ? ? 
ATOM   1570 C CB    . MET A 1 222 ? -4.226  11.266 31.564 1.000 28.003  0 203 MET A CB    1 ? ? 
ATOM   1571 C CG    . MET A 1 222 ? -5.638  10.875 31.964 1.000 32.500  0 203 MET A CG    1 ? ? 
ATOM   1572 S SD    . MET A 1 222 ? -6.893  11.831 31.092 1.000 38.555  0 203 MET A SD    1 ? ? 
ATOM   1573 C CE    . MET A 1 222 ? -8.287  11.622 32.194 1.000 32.956  0 203 MET A CE    1 ? ? 
ATOM   1574 N N     . LEU A 1 223 ? -5.136  14.098 32.757 1.000 24.709  0 204 LEU A N     1 ? ? 
ATOM   1575 C CA    . LEU A 1 223 ? -5.216  14.817 34.024 1.000 23.813  0 204 LEU A CA    1 ? ? 
ATOM   1576 C C     . LEU A 1 223 ? -5.407  13.842 35.179 1.000 21.606  0 204 LEU A C     1 ? ? 
ATOM   1577 O O     . LEU A 1 223 ? -6.163  12.876 35.079 1.000 22.012  0 204 LEU A O     1 ? ? 
ATOM   1578 C CB    . LEU A 1 223 ? -6.367  15.821 34.011 1.000 23.904  0 204 LEU A CB    1 ? ? 
ATOM   1579 C CG    . LEU A 1 223 ? -6.019  17.239 33.586 1.000 25.713  0 204 LEU A CG    1 ? ? 
ATOM   1580 C CD1   . LEU A 1 223 ? -5.573  17.291 32.120 1.000 27.236  0 204 LEU A CD1   1 ? ? 
ATOM   1581 C CD2   . LEU A 1 223 ? -7.232  18.122 33.841 1.000 26.609  0 204 LEU A CD2   1 ? ? 
ATOM   1582 N N     . VAL A 1 224 ? -4.712  14.127 36.277 1.000 19.125  0 205 VAL A N     1 ? ? 
ATOM   1583 C CA    . VAL A 1 224 ? -4.683  13.240 37.421 1.000 18.701  0 205 VAL A CA    1 ? ? 
ATOM   1584 C C     . VAL A 1 224 ? -4.738  14.052 38.701 1.000 18.841  0 205 VAL A C     1 ? ? 
ATOM   1585 O O     . VAL A 1 224 ? -3.991  15.009 38.864 1.000 18.836  0 205 VAL A O     1 ? ? 
ATOM   1586 C CB    . VAL A 1 224 ? -3.395  12.419 37.435 1.000 17.880  0 205 VAL A CB    1 ? ? 
ATOM   1587 C CG1   . VAL A 1 224 ? -3.290  11.607 38.700 1.000 17.358  0 205 VAL A CG1   1 ? ? 
ATOM   1588 C CG2   . VAL A 1 224 ? -3.235  11.589 36.182 1.000 17.442  0 205 VAL A CG2   1 ? ? 
ATOM   1589 N N     . ARG A 1 225 ? -5.548  13.570 39.642 1.000 19.316  0 206 ARG A N     1 ? ? 
ATOM   1590 C CA    . ARG A 1 225 ? -5.666  14.228 40.934 1.000 19.669  0 206 ARG A CA    1 ? ? 
ATOM   1591 C C     . ARG A 1 225 ? -4.635  13.635 41.883 1.000 18.973  0 206 ARG A C     1 ? ? 
ATOM   1592 O O     . ARG A 1 225 ? -4.607  12.435 42.099 1.000 19.587  0 206 ARG A O     1 ? ? 
ATOM   1593 C CB    . ARG A 1 225 ? -7.078  14.059 41.505 1.000 19.577  0 206 ARG A CB    1 ? ? 
ATOM   1594 C CG    . ARG A 1 225 ? -7.258  14.609 42.918 1.000 19.857  0 206 ARG A CG    1 ? ? 
ATOM   1595 C CD    . ARG A 1 225 ? -7.199  16.129 42.973 1.000 19.893  0 206 ARG A CD    1 ? ? 
ATOM   1596 N NE    . ARG A 1 225 ? -7.381  16.683 44.311 1.000 21.135  0 206 ARG A NE    1 ? ? 
ATOM   1597 C CZ    . ARG A 1 225 ? -7.721  17.950 44.582 1.000 21.379  0 206 ARG A CZ    1 ? ? 
ATOM   1598 N NH1   . ARG A 1 225 ? -7.924  18.796 43.596 1.000 21.574  0 206 ARG A NH1   1 ? ? 
ATOM   1599 N NH2   . ARG A 1 225 ? -7.874  18.375 45.825 1.000 22.256  0 206 ARG A NH2   1 ? ? 
ATOM   1600 N N     . ASN A 1 226 ? -3.805  14.487 42.454 1.000 18.668  0 207 ASN A N     1 ? ? 
ATOM   1601 C CA    . ASN A 1 226 ? -2.848  14.033 43.443 1.000 19.610  0 207 ASN A CA    1 ? ? 
ATOM   1602 C C     . ASN A 1 226 ? -3.515  13.986 44.821 1.000 19.833  0 207 ASN A C     1 ? ? 
ATOM   1603 O O     . ASN A 1 226 ? -4.166  14.957 45.239 1.000 21.557  0 207 ASN A O     1 ? ? 
ATOM   1604 C CB    . ASN A 1 226 ? -1.630  14.952 43.413 1.000 20.218  0 207 ASN A CB    1 ? ? 
ATOM   1605 C CG    . ASN A 1 226 ? -0.449  14.390 44.161 1.000 20.730  0 207 ASN A CG    1 ? ? 
ATOM   1606 O OD1   . ASN A 1 226 ? -0.590  14.012 45.326 1.000 21.260  0 207 ASN A OD1   1 ? ? 
ATOM   1607 N ND2   . ASN A 1 226 ? 0.696   14.346 43.497 1.000 19.520  0 207 ASN A ND2   1 ? ? 
ATOM   1608 N N     . PRO A 1 227 ? -3.467  12.837 45.534 1.000 19.406  0 208 PRO A N     1 ? ? 
ATOM   1609 C CA    . PRO A 1 227 ? -4.093  12.731 46.852 1.000 20.514  0 208 PRO A CA    1 ? ? 
ATOM   1610 C C     . PRO A 1 227 ? -3.511  13.649 47.918 1.000 21.270  0 208 PRO A C     1 ? ? 
ATOM   1611 O O     . PRO A 1 227 ? -4.136  13.858 48.964 1.000 23.443  0 208 PRO A O     1 ? ? 
ATOM   1612 C CB    . PRO A 1 227 ? -3.880  11.265 47.270 1.000 20.524  0 208 PRO A CB    1 ? ? 
ATOM   1613 C CG    . PRO A 1 227 ? -2.861  10.710 46.315 1.000 19.150  0 208 PRO A CG    1 ? ? 
ATOM   1614 C CD    . PRO A 1 227 ? -2.923  11.555 45.068 1.000 19.144  0 208 PRO A CD    1 ? ? 
ATOM   1615 N N     . LEU A 1 228 ? -2.299  14.158 47.664 1.000 20.480  0 209 LEU A N     1 ? ? 
ATOM   1616 C CA    . LEU A 1 228 ? -1.650  15.065 48.594 1.000 20.283  0 209 LEU A CA    1 ? ? 
ATOM   1617 C C     . LEU A 1 228 ? -2.149  16.499 48.405 1.000 21.272  0 209 LEU A C     1 ? ? 
ATOM   1618 O O     . LEU A 1 228 ? -1.737  17.393 49.158 1.000 22.485  0 209 LEU A O     1 ? ? 
ATOM   1619 C CB    . LEU A 1 228 ? -0.138  14.985 48.378 1.000 19.043  0 209 LEU A CB    1 ? ? 
ATOM   1620 C CG    . LEU A 1 228 ? 0.549   13.671 48.747 1.000 18.600  0 209 LEU A CG    1 ? ? 
ATOM   1621 C CD1   . LEU A 1 228 ? 1.821   13.487 47.930 1.000 17.450  0 209 LEU A CD1   1 ? ? 
ATOM   1622 C CD2   . LEU A 1 228 ? 0.906   13.636 50.218 1.000 17.916  0 209 LEU A CD2   1 ? ? 
ATOM   1623 N N     . SER A 1 229 ? -2.995  16.698 47.378 1.000 20.768  0 210 SER A N     1 ? ? 
ATOM   1624 C CA    . SER A 1 229 ? -3.680  17.970 47.157 1.000 21.995  0 210 SER A CA    1 ? ? 
ATOM   1625 C C     . SER A 1 229 ? -4.763  18.196 48.207 1.000 21.589  0 210 SER A C     1 ? ? 
ATOM   1626 O O     . SER A 1 229 ? -5.485  17.260 48.554 1.000 21.493  0 210 SER A O     1 ? ? 
ATOM   1627 C CB    . SER A 1 229 ? -4.322  18.046 45.782 1.000 21.930  0 210 SER A CB    1 ? ? 
ATOM   1628 O OG    . SER A 1 229 ? -3.351  18.186 44.747 1.000 22.167  0 210 SER A OG    1 ? ? 
ATOM   1629 N N     . ARG A 1 230 ? -4.894  19.454 48.656 1.000 22.441  0 211 ARG A N     1 ? ? 
ATOM   1630 C CA    . ARG A 1 230 ? -5.858  19.833 49.670 1.000 23.019  0 211 ARG A CA    1 ? ? 
ATOM   1631 C C     . ARG A 1 230 ? -7.213  20.025 49.009 1.000 21.080  0 211 ARG A C     1 ? ? 
ATOM   1632 O O     . ARG A 1 230 ? -7.315  20.310 47.819 1.000 20.810  0 211 ARG A O     1 ? ? 
ATOM   1633 C CB    . ARG A 1 230 ? -5.386  21.099 50.387 1.000 26.358  0 211 ARG A CB    1 ? ? 
ATOM   1634 C CG    . ARG A 1 230 ? -4.441  20.805 51.537 1.000 28.535  0 211 ARG A CG    1 ? ? 
ATOM   1635 C CD    . ARG A 1 230 ? -3.698  22.066 51.872 1.000 31.744  0 211 ARG A CD    1 ? ? 
ATOM   1636 N NE    . ARG A 1 230 ? -2.530  21.655 52.624 1.000 37.533  0 211 ARG A NE    1 ? ? 
ATOM   1637 C CZ    . ARG A 1 230 ? -1.887  22.403 53.508 1.000 41.155  0 211 ARG A CZ    1 ? ? 
ATOM   1638 N NH1   . ARG A 1 230 ? -0.883  21.887 54.174 1.000 42.248  0 211 ARG A NH1   1 ? ? 
ATOM   1639 N NH2   . ARG A 1 230 ? -2.318  23.613 53.843 1.000 41.683  0 211 ARG A NH2   1 ? ? 
ATOM   1640 N N     . ASN A 1 231 ? -8.262  19.858 49.805 1.000 21.396  0 212 ASN A N     1 ? ? 
ATOM   1641 C CA    . ASN A 1 231 ? -9.613  19.990 49.294 1.000 20.547  0 212 ASN A CA    1 ? ? 
ATOM   1642 C C     . ASN A 1 231 ? -9.898  21.436 48.914 1.000 19.560  0 212 ASN A C     1 ? ? 
ATOM   1643 O O     . ASN A 1 231 ? -10.789 21.698 48.110 1.000 19.162  0 212 ASN A O     1 ? ? 
ATOM   1644 C CB    . ASN A 1 231 ? -10.620 19.533 50.338 1.000 22.267  0 212 ASN A CB    1 ? ? 
ATOM   1645 C CG    . ASN A 1 231 ? -10.494 18.065 50.658 1.000 23.316  0 212 ASN A CG    1 ? ? 
ATOM   1646 O OD1   . ASN A 1 231 ? -10.264 17.250 49.775 1.000 25.610  0 212 ASN A OD1   1 ? ? 
ATOM   1647 N ND2   . ASN A 1 231 ? -10.628 17.724 51.924 1.000 22.482  0 212 ASN A ND2   1 ? ? 
ATOM   1648 N N     . SER A 1 232 ? -9.102  22.365 49.461 1.000 18.215  0 213 SER A N     1 ? ? 
ATOM   1649 C CA    . SER A 1 232 ? -9.209  23.789 49.207 1.000 16.919  0 213 SER A CA    1 ? ? 
ATOM   1650 C C     . SER A 1 232 ? -8.834  24.164 47.764 1.000 16.696  0 213 SER A C     1 ? ? 
ATOM   1651 O O     . SER A 1 232 ? -8.951  25.327 47.383 1.000 16.156  0 213 SER A O     1 ? ? 
ATOM   1652 C CB    . SER A 1 232 ? -8.396  24.535 50.219 1.000 16.949  0 213 SER A CB    1 ? ? 
ATOM   1653 O OG    . SER A 1 232 ? -7.092  24.004 50.305 1.000 17.807  0 213 SER A OG    1 ? ? 
ATOM   1654 N N     . THR A 1 233 ? -8.364  23.201 46.962 1.000 16.537  0 214 THR A N     1 ? ? 
ATOM   1655 C CA    . THR A 1 233 ? -8.001  23.488 45.579 1.000 16.932  0 214 THR A CA    1 ? ? 
ATOM   1656 C C     . THR A 1 233 ? -8.458  22.342 44.695 1.000 16.688  0 214 THR A C     1 ? ? 
ATOM   1657 O O     . THR A 1 233 ? -8.420  21.186 45.108 1.000 17.480  0 214 THR A O     1 ? ? 
ATOM   1658 C CB    . THR A 1 233 ? -6.487  23.683 45.387 1.000 17.869  0 214 THR A CB    1 ? ? 
ATOM   1659 O OG1   . THR A 1 233 ? -6.291  23.853 43.981 1.000 18.225  0 214 THR A OG1   1 ? ? 
ATOM   1660 C CG2   . THR A 1 233 ? -5.672  22.528 45.939 1.000 16.799  0 214 THR A CG2   1 ? ? 
ATOM   1661 N N     . HIS A 1 234 ? -8.858  22.699 43.476 1.000 16.755  0 215 HIS A N     1 ? ? 
ATOM   1662 C CA    . HIS A 1 234 ? -9.342  21.765 42.473 1.000 16.931  0 215 HIS A CA    1 ? ? 
ATOM   1663 C C     . HIS A 1 234 ? -8.227  21.386 41.498 1.000 17.283  0 215 HIS A C     1 ? ? 
ATOM   1664 O O     . HIS A 1 234 ? -8.487  20.765 40.469 1.000 17.201  0 215 HIS A O     1 ? ? 
ATOM   1665 C CB    . HIS A 1 234 ? -10.522 22.390 41.718 1.000 16.995  0 215 HIS A CB    1 ? ? 
ATOM   1666 C CG    . HIS A 1 234 ? -11.504 21.395 41.196 1.000 18.116  0 215 HIS A CG    1 ? ? 
ATOM   1667 N ND1   . HIS A 1 234 ? -11.171 20.474 40.221 1.000 18.228  0 215 HIS A ND1   1 ? ? 
ATOM   1668 C CD2   . HIS A 1 234 ? -12.809 21.184 41.491 1.000 18.056  0 215 HIS A CD2   1 ? ? 
ATOM   1669 C CE1   . HIS A 1 234 ? -12.223 19.741 39.932 1.000 18.077  0 215 HIS A CE1   1 ? ? 
ATOM   1670 N NE2   . HIS A 1 234 ? -13.239 20.162 40.697 1.000 18.115  0 215 HIS A NE2   1 ? ? 
ATOM   1671 N N     . GLU A 1 235 ? -6.988  21.764 41.819 1.000 17.753  0 216 GLU A N     1 ? ? 
ATOM   1672 C CA    . GLU A 1 235 ? -5.864  21.516 40.931 1.000 18.187  0 216 GLU A CA    1 ? ? 
ATOM   1673 C C     . GLU A 1 235 ? -5.786  20.048 40.525 1.000 18.777  0 216 GLU A C     1 ? ? 
ATOM   1674 O O     . GLU A 1 235 ? -5.935  19.143 41.337 1.000 19.423  0 216 GLU A O     1 ? ? 
ATOM   1675 C CB    . GLU A 1 235 ? -4.549  21.909 41.594 1.000 17.050  0 216 GLU A CB    1 ? ? 
ATOM   1676 C CG    . GLU A 1 235 ? -4.247  21.064 42.797 1.000 17.456  0 216 GLU A CG    1 ? ? 
ATOM   1677 C CD    . GLU A 1 235 ? -3.015  21.463 43.578 1.000 18.080  0 216 GLU A CD    1 ? ? 
ATOM   1678 O OE1   . GLU A 1 235 ? -2.519  20.626 44.273 1.000 17.715  0 216 GLU A OE1   1 ? ? 
ATOM   1679 O OE2   . GLU A 1 235 ? -2.485  22.585 43.413 1.000 16.999  0 216 GLU A OE2   1 ? ? 
ATOM   1680 N N     . MET A 1 236 ? -5.481  19.842 39.249 1.000 19.218  0 217 MET A N     1 ? ? 
ATOM   1681 C CA    . MET A 1 236 ? -5.144  18.549 38.703 1.000 20.140  0 217 MET A CA    1 ? ? 
ATOM   1682 C C     . MET A 1 236 ? -3.883  18.714 37.862 1.000 21.586  0 217 MET A C     1 ? ? 
ATOM   1683 O O     . MET A 1 236 ? -3.532  19.825 37.460 1.000 23.135  0 217 MET A O     1 ? ? 
ATOM   1684 C CB    . MET A 1 236 ? -6.324  18.050 37.864 1.000 20.675  0 217 MET A CB    1 ? ? 
ATOM   1685 C CG    . MET A 1 236 ? -7.489  17.667 38.775 1.000 22.001  0 217 MET A CG    1 ? ? 
ATOM   1686 S SD    . MET A 1 236 ? -8.945  17.094 37.893 1.000 23.509  0 217 MET A SD    1 ? ? 
ATOM   1687 C CE    . MET A 1 236 ? -8.344  15.494 37.358 1.000 22.290  0 217 MET A CE    1 ? ? 
ATOM   1688 N N     . TYR A 1 237 ? -3.170  17.605 37.647 1.000 20.747  0 218 TYR A N     1 ? ? 
ATOM   1689 C CA    . TYR A 1 237 ? -1.917  17.697 36.921 1.000 20.217  0 218 TYR A CA    1 ? ? 
ATOM   1690 C C     . TYR A 1 237 ? -2.045  16.982 35.583 1.000 20.762  0 218 TYR A C     1 ? ? 
ATOM   1691 O O     . TYR A 1 237 ? -2.477  15.841 35.535 1.000 21.045  0 218 TYR A O     1 ? ? 
ATOM   1692 C CB    . TYR A 1 237 ? -0.751  17.180 37.761 1.000 18.929  0 218 TYR A CB    1 ? ? 
ATOM   1693 C CG    . TYR A 1 237 ? -0.383  18.088 38.903 1.000 17.833  0 218 TYR A CG    1 ? ? 
ATOM   1694 C CD1   . TYR A 1 237 ? -1.156  18.132 40.053 1.000 16.863  0 218 TYR A CD1   1 ? ? 
ATOM   1695 C CD2   . TYR A 1 237 ? 0.739   18.900 38.831 1.000 17.413  0 218 TYR A CD2   1 ? ? 
ATOM   1696 C CE1   . TYR A 1 237 ? -0.833  18.955 41.117 1.000 16.461  0 218 TYR A CE1   1 ? ? 
ATOM   1697 C CE2   . TYR A 1 237 ? 1.073   19.745 39.877 1.000 16.797  0 218 TYR A CE2   1 ? ? 
ATOM   1698 C CZ    . TYR A 1 237 ? 0.282   19.766 41.020 1.000 16.843  0 218 TYR A CZ    1 ? ? 
ATOM   1699 O OH    . TYR A 1 237 ? 0.578   20.597 42.054 1.000 16.460  0 218 TYR A OH    1 ? ? 
ATOM   1700 N N     . TRP A 1 238 ? -1.700  17.693 34.503 1.000 20.026  0 219 TRP A N     1 ? ? 
ATOM   1701 C CA    . TRP A 1 238 ? -1.600  17.108 33.182 1.000 19.548  0 219 TRP A CA    1 ? ? 
ATOM   1702 C C     . TRP A 1 238 ? -0.250  16.406 33.077 1.000 21.265  0 219 TRP A C     1 ? ? 
ATOM   1703 O O     . TRP A 1 238 ? 0.779   17.074 32.997 1.000 22.490  0 219 TRP A O     1 ? ? 
ATOM   1704 C CB    . TRP A 1 238 ? -1.757  18.204 32.120 1.000 19.101  0 219 TRP A CB    1 ? ? 
ATOM   1705 C CG    . TRP A 1 238 ? -1.686  17.690 30.713 1.000 18.642  0 219 TRP A CG    1 ? ? 
ATOM   1706 C CD1   . TRP A 1 238 ? -2.053  16.451 30.274 1.000 18.912  0 219 TRP A CD1   1 ? ? 
ATOM   1707 C CD2   . TRP A 1 238 ? -1.198  18.392 29.556 1.000 18.103  0 219 TRP A CD2   1 ? ? 
ATOM   1708 N NE1   . TRP A 1 238 ? -1.844  16.344 28.928 1.000 18.343  0 219 TRP A NE1   1 ? ? 
ATOM   1709 C CE2   . TRP A 1 238 ? -1.320  17.517 28.455 1.000 17.762  0 219 TRP A CE2   1 ? ? 
ATOM   1710 C CE3   . TRP A 1 238 ? -0.658  19.665 29.346 1.000 18.917  0 219 TRP A CE3   1 ? ? 
ATOM   1711 C CZ2   . TRP A 1 238 ? -0.916  17.867 27.163 1.000 17.634  0 219 TRP A CZ2   1 ? ? 
ATOM   1712 C CZ3   . TRP A 1 238 ? -0.278  20.017 28.064 1.000 19.598  0 219 TRP A CZ3   1 ? ? 
ATOM   1713 C CH2   . TRP A 1 238 ? -0.399  19.127 26.988 1.000 18.060  0 219 TRP A CH2   1 ? ? 
ATOM   1714 N N     . ILE A 1 239 ? -0.262  15.063 33.113 1.000 22.548  0 220 ILE A N     1 ? ? 
ATOM   1715 C CA    . ILE A 1 239 ? 0.954   14.253 33.062 1.000 23.371  0 220 ILE A CA    1 ? ? 
ATOM   1716 C C     . ILE A 1 239 ? 1.056   13.602 31.683 1.000 24.863  0 220 ILE A C     1 ? ? 
ATOM   1717 O O     . ILE A 1 239 ? 0.034   13.401 31.027 1.000 25.010  0 220 ILE A O     1 ? ? 
ATOM   1718 C CB    . ILE A 1 239 ? 0.993   13.223 34.219 1.000 22.874  0 220 ILE A CB    1 ? ? 
ATOM   1719 C CG1   . ILE A 1 239 ? -0.323  12.456 34.348 1.000 23.522  0 220 ILE A CG1   1 ? ? 
ATOM   1720 C CG2   . ILE A 1 239 ? 1.336   13.892 35.549 1.000 23.033  0 220 ILE A CG2   1 ? ? 
ATOM   1721 C CD1   . ILE A 1 239 ? -0.473  11.214 33.507 1.000 23.816  0 220 ILE A CD1   1 ? ? 
ATOM   1722 N N     . SER A 1 240 ? 2.282   13.285 31.250 1.000 25.587  0 221 SER A N     1 ? ? 
ATOM   1723 C CA    . SER A 1 240 ? 2.495   12.850 29.878 1.000 27.846  0 221 SER A CA    1 ? ? 
ATOM   1724 C C     . SER A 1 240 ? 2.055   11.400 29.651 1.000 30.178  0 221 SER A C     1 ? ? 
ATOM   1725 O O     . SER A 1 240 ? 1.529   11.072 28.588 1.000 31.782  0 221 SER A O     1 ? ? 
ATOM   1726 C CB    . SER A 1 240 ? 3.918   13.079 29.472 1.000 27.096  0 221 SER A CB    1 ? ? 
ATOM   1727 O OG    . SER A 1 240 ? 4.755   12.504 30.431 1.000 28.551  0 221 SER A OG    1 ? ? 
ATOM   1728 N N     . ASN A 1 241 ? 2.261   10.530 30.649 1.000 29.576  0 222 ASN A N     1 ? ? 
ATOM   1729 C CA    . ASN A 1 241 ? 2.089   9.092  30.462 1.000 30.235  0 222 ASN A CA    1 ? ? 
ATOM   1730 C C     . ASN A 1 241 ? 0.752   8.594  31.003 1.000 30.895  0 222 ASN A C     1 ? ? 
ATOM   1731 O O     . ASN A 1 241 ? 0.654   8.062  32.109 1.000 32.731  0 222 ASN A O     1 ? ? 
ATOM   1732 C CB    . ASN A 1 241 ? 3.227   8.291  31.076 1.000 28.942  0 222 ASN A CB    1 ? ? 
ATOM   1733 C CG    . ASN A 1 241 ? 4.550   8.968  30.832 1.000 27.706  0 222 ASN A CG    1 ? ? 
ATOM   1734 O OD1   . ASN A 1 241 ? 4.813   9.532  29.762 1.000 27.968  0 222 ASN A OD1   1 ? ? 
ATOM   1735 N ND2   . ASN A 1 241 ? 5.402   8.898  31.828 1.000 25.467  0 222 ASN A ND2   1 ? ? 
ATOM   1736 N N     . GLY A 1 242 ? -0.264  8.732  30.164 1.000 31.497  0 223 GLY A N     1 ? ? 
ATOM   1737 C CA    . GLY A 1 242 ? -1.604  8.293  30.494 1.000 33.429  0 223 GLY A CA    1 ? ? 
ATOM   1738 C C     . GLY A 1 242 ? -2.545  8.668  29.358 1.000 35.955  0 223 GLY A C     1 ? ? 
ATOM   1739 O O     . GLY A 1 242 ? -2.164  9.434  28.471 1.000 36.391  0 223 GLY A O     1 ? ? 
ATOM   1740 N N     . THR A 1 243 ? -3.751  8.089  29.388 1.000 37.349  0 224 THR A N     1 ? ? 
ATOM   1741 C CA    . THR A 1 243 ? -4.823  8.423  28.465 1.000 37.367  0 224 THR A CA    1 ? ? 
ATOM   1742 C C     . THR A 1 243 ? -6.112  8.462  29.275 1.000 36.574  0 224 THR A C     1 ? ? 
ATOM   1743 O O     . THR A 1 243 ? -6.140  8.049  30.437 1.000 34.341  0 224 THR A O     1 ? ? 
ATOM   1744 C CB    . THR A 1 243 ? -4.953  7.393  27.331 1.000 38.677  0 224 THR A CB    1 ? ? 
ATOM   1745 O OG1   . THR A 1 243 ? -5.081  6.092  27.910 1.000 37.420  0 224 THR A OG1   1 ? ? 
ATOM   1746 C CG2   . THR A 1 243 ? -3.814  7.423  26.327 1.000 40.006  0 224 THR A CG2   1 ? ? 
ATOM   1747 N N     . GLY A 1 244 ? -7.165  8.999  28.663 1.000 35.319  0 225 GLY A N     1 ? ? 
ATOM   1748 C CA    . GLY A 1 244 ? -8.460  8.918  29.301 1.000 32.355  0 225 GLY A CA    1 ? ? 
ATOM   1749 C C     . GLY A 1 244 ? -9.286  10.165 29.048 1.000 33.064  0 225 GLY A C     1 ? ? 
ATOM   1750 O O     . GLY A 1 244 ? -8.835  11.121 28.430 1.000 33.730  0 225 GLY A O     1 ? ? 
ATOM   1751 N N     . ASN A 1 245 ? -10.485 10.179 29.616 1.000 33.808  0 226 ASN A N     1 ? ? 
ATOM   1752 C CA    . ASN A 1 245 ? -11.408 11.261 29.343 1.000 36.809  0 226 ASN A CA    1 ? ? 
ATOM   1753 C C     . ASN A 1 245 ? -11.163 12.390 30.332 1.000 40.814  0 226 ASN A C     1 ? ? 
ATOM   1754 O O     . ASN A 1 245 ? -11.247 12.142 31.535 1.000 44.245  0 226 ASN A O     1 ? ? 
ATOM   1755 C CB    . ASN A 1 245 ? -12.852 10.769 29.425 1.000 35.836  0 226 ASN A CB    1 ? ? 
ATOM   1756 C CG    . ASN A 1 245 ? -13.847 11.801 28.945 1.000 35.271  0 226 ASN A CG    1 ? ? 
ATOM   1757 O OD1   . ASN A 1 245 ? -14.252 12.663 29.726 1.000 37.128  0 226 ASN A OD1   1 ? ? 
ATOM   1758 N ND2   . ASN A 1 245 ? -14.223 11.736 27.674 1.000 34.531  0 226 ASN A ND2   1 ? ? 
ATOM   1759 N N     . ILE A 1 246 ? -10.872 13.604 29.829 1.000 39.034  0 227 ILE A N     1 ? ? 
ATOM   1760 C CA    . ILE A 1 246 ? -10.588 14.726 30.714 1.000 36.404  0 227 ILE A CA    1 ? ? 
ATOM   1761 C C     . ILE A 1 246 ? -11.843 15.110 31.502 1.000 35.773  0 227 ILE A C     1 ? ? 
ATOM   1762 O O     . ILE A 1 246 ? -11.810 15.200 32.739 1.000 34.515  0 227 ILE A O     1 ? ? 
ATOM   1763 C CB    . ILE A 1 246 ? -9.935  15.903 29.961 1.000 36.098  0 227 ILE A CB    1 ? ? 
ATOM   1764 C CG1   . ILE A 1 246 ? -8.490  15.549 29.624 1.000 35.753  0 227 ILE A CG1   1 ? ? 
ATOM   1765 C CG2   . ILE A 1 246 ? -9.981  17.179 30.792 1.000 34.556  0 227 ILE A CG2   1 ? ? 
ATOM   1766 C CD1   . ILE A 1 246 ? -7.820  16.553 28.740 1.000 32.986  0 227 ILE A CD1   1 ? ? 
ATOM   1767 N N     . VAL A 1 247 ? -12.955 15.319 30.780 1.000 35.330  0 228 VAL A N     1 ? ? 
ATOM   1768 C CA    . VAL A 1 247 ? -14.188 15.730 31.435 1.000 36.916  0 228 VAL A CA    1 ? ? 
ATOM   1769 C C     . VAL A 1 247 ? -14.561 14.759 32.562 1.000 36.356  0 228 VAL A C     1 ? ? 
ATOM   1770 O O     . VAL A 1 247 ? -14.903 15.196 33.661 1.000 34.707  0 228 VAL A O     1 ? ? 
ATOM   1771 C CB    . VAL A 1 247 ? -15.333 15.974 30.432 1.000 37.430  0 228 VAL A CB    1 ? ? 
ATOM   1772 C CG1   . VAL A 1 247 ? -16.700 16.079 31.103 1.000 38.118  0 228 VAL A CG1   1 ? ? 
ATOM   1773 C CG2   . VAL A 1 247 ? -15.078 17.244 29.642 1.000 36.197  0 228 VAL A CG2   1 ? ? 
ATOM   1774 N N     . SER A 1 248 ? -14.507 13.448 32.298 1.000 35.462  0 229 SER A N     1 ? ? 
ATOM   1775 C CA    . SER A 1 248 ? -14.848 12.469 33.324 1.000 35.502  0 229 SER A CA    1 ? ? 
ATOM   1776 C C     . SER A 1 248 ? -13.973 12.653 34.564 1.000 33.090  0 229 SER A C     1 ? ? 
ATOM   1777 O O     . SER A 1 248 ? -14.495 12.729 35.682 1.000 34.232  0 229 SER A O     1 ? ? 
ATOM   1778 C CB    . SER A 1 248 ? -14.733 11.048 32.825 1.000 37.879  0 229 SER A CB    1 ? ? 
ATOM   1779 O OG    . SER A 1 248 ? -15.298 10.895 31.542 1.000 44.481  0 229 SER A OG    1 ? ? 
ATOM   1780 N N     . SER A 1 249 ? -12.648 12.770 34.354 1.000 29.711  0 230 SER A N     1 ? ? 
ATOM   1781 C CA    . SER A 1 249 ? -11.713 12.840 35.473 1.000 28.251  0 230 SER A CA    1 ? ? 
ATOM   1782 C C     . SER A 1 249 ? -12.013 14.073 36.323 1.000 27.631  0 230 SER A C     1 ? ? 
ATOM   1783 O O     . SER A 1 249 ? -12.044 13.988 37.553 1.000 27.498  0 230 SER A O     1 ? ? 
ATOM   1784 C CB    . SER A 1 249 ? -10.263 12.770 35.038 1.000 27.816  0 230 SER A CB    1 ? ? 
ATOM   1785 O OG    . SER A 1 249 ? -9.882  13.894 34.250 1.000 29.503  0 230 SER A OG    1 ? ? 
ATOM   1786 N N     . VAL A 1 250 ? -12.322 15.186 35.639 1.000 25.492  0 231 VAL A N     1 ? ? 
ATOM   1787 C CA    . VAL A 1 250 ? -12.565 16.458 36.296 1.000 25.661  0 231 VAL A CA    1 ? ? 
ATOM   1788 C C     . VAL A 1 250 ? -13.837 16.349 37.147 1.000 25.392  0 231 VAL A C     1 ? ? 
ATOM   1789 O O     . VAL A 1 250 ? -13.857 16.731 38.323 1.000 23.491  0 231 VAL A O     1 ? ? 
ATOM   1790 C CB    . VAL A 1 250 ? -12.611 17.636 35.295 1.000 25.447  0 231 VAL A CB    1 ? ? 
ATOM   1791 C CG1   . VAL A 1 250 ? -13.141 18.909 35.955 1.000 24.265  0 231 VAL A CG1   1 ? ? 
ATOM   1792 C CG2   . VAL A 1 250 ? -11.270 17.858 34.597 1.000 24.104  0 231 VAL A CG2   1 ? ? 
ATOM   1793 N N     . ASN A 1 251 ? -14.900 15.783 36.571 1.000 25.671  0 232 ASN A N     1 ? ? 
ATOM   1794 C CA    . ASN A 1 251 ? -16.148 15.695 37.306 1.000 27.943  0 232 ASN A CA    1 ? ? 
ATOM   1795 C C     . ASN A 1 251 ? -16.009 14.801 38.539 1.000 28.096  0 232 ASN A C     1 ? ? 
ATOM   1796 O O     . ASN A 1 251 ? -16.725 14.967 39.529 1.000 24.974  0 232 ASN A O     1 ? ? 
ATOM   1797 C CB    . ASN A 1 251 ? -17.279 15.209 36.404 1.000 29.289  0 232 ASN A CB    1 ? ? 
ATOM   1798 C CG    . ASN A 1 251 ? -17.802 16.314 35.515 1.000 31.416  0 232 ASN A CG    1 ? ? 
ATOM   1799 O OD1   . ASN A 1 251 ? -18.007 17.451 35.962 1.000 30.924  0 232 ASN A OD1   1 ? ? 
ATOM   1800 N ND2   . ASN A 1 251 ? -18.007 15.986 34.251 1.000 31.800  0 232 ASN A ND2   1 ? ? 
ATOM   1801 N N     . MET A 1 252 ? -15.107 13.825 38.454 1.000 30.259  0 233 MET A N     1 ? ? 
ATOM   1802 C CA    . MET A 1 252 ? -14.930 12.879 39.541 1.000 31.871  0 233 MET A CA    1 ? ? 
ATOM   1803 C C     . MET A 1 252 ? -14.329 13.605 40.737 1.000 30.184  0 233 MET A C     1 ? ? 
ATOM   1804 O O     . MET A 1 252 ? -14.702 13.357 41.880 1.000 31.090  0 233 MET A O     1 ? ? 
ATOM   1805 C CB    . MET A 1 252 ? -13.954 11.790 39.097 1.000 36.214  0 233 MET A CB    1 ? ? 
ATOM   1806 C CG    . MET A 1 252 ? -14.383 10.379 39.274 1.000 42.676  0 233 MET A CG    1 ? ? 
ATOM   1807 S SD    . MET A 1 252 ? -15.990 9.927  39.983 1.000 56.019  0 233 MET A SD    1 ? ? 
ATOM   1808 C CE    . MET A 1 252 ? -15.638 9.981  41.747 1.000 48.189  0 233 MET A CE    1 ? ? 
ATOM   1809 N N     . VAL A 1 253 ? -13.383 14.498 40.466 1.000 29.022  0 234 VAL A N     1 ? ? 
ATOM   1810 C CA    . VAL A 1 253 ? -12.778 15.279 41.528 1.000 27.509  0 234 VAL A CA    1 ? ? 
ATOM   1811 C C     . VAL A 1 253 ? -13.809 16.249 42.095 1.000 26.232  0 234 VAL A C     1 ? ? 
ATOM   1812 O O     . VAL A 1 253 ? -13.876 16.425 43.308 1.000 28.767  0 234 VAL A O     1 ? ? 
ATOM   1813 C CB    . VAL A 1 253 ? -11.514 15.994 41.016 1.000 25.941  0 234 VAL A CB    1 ? ? 
ATOM   1814 C CG1   . VAL A 1 253 ? -10.947 16.930 42.064 1.000 24.830  0 234 VAL A CG1   1 ? ? 
ATOM   1815 C CG2   . VAL A 1 253 ? -10.444 15.006 40.599 1.000 25.054  0 234 VAL A CG2   1 ? ? 
ATOM   1816 N N     . SER A 1 254 ? -14.613 16.868 41.225 1.000 24.921  0 235 SER A N     1 ? ? 
ATOM   1817 C CA    . SER A 1 254 ? -15.636 17.774 41.714 1.000 24.109  0 235 SER A CA    1 ? ? 
ATOM   1818 C C     . SER A 1 254 ? -16.582 17.027 42.655 1.000 23.827  0 235 SER A C     1 ? ? 
ATOM   1819 O O     . SER A 1 254 ? -16.945 17.534 43.718 1.000 23.814  0 235 SER A O     1 ? ? 
ATOM   1820 C CB    . SER A 1 254 ? -16.384 18.410 40.589 1.000 23.532  0 235 SER A CB    1 ? ? 
ATOM   1821 O OG    . SER A 1 254 ? -15.532 19.149 39.746 1.000 23.926  0 235 SER A OG    1 ? ? 
ATOM   1822 N N     . ARG A 1 255 ? -16.955 15.806 42.265 1.000 23.183  0 236 ARG A N     1 ? ? 
ATOM   1823 C CA    . ARG A 1 255 ? -17.876 15.035 43.075 1.000 25.563  0 236 ARG A CA    1 ? ? 
ATOM   1824 C C     . ARG A 1 255 ? -17.227 14.777 44.431 1.000 23.540  0 236 ARG A C     1 ? ? 
ATOM   1825 O O     . ARG A 1 255 ? -17.800 15.111 45.461 1.000 21.120  0 236 ARG A O     1 ? ? 
ATOM   1826 C CB    . ARG A 1 255 ? -18.305 13.754 42.352 1.000 30.815  0 236 ARG A CB    1 ? ? 
ATOM   1827 C CG    . ARG A 1 255 ? -19.406 13.990 41.339 1.000 37.480  0 236 ARG A CG    1 ? ? 
ATOM   1828 C CD    . ARG A 1 255 ? -19.856 12.735 40.579 1.000 40.790  0 236 ARG A CD    1 ? ? 
ATOM   1829 N NE    . ARG A 1 255 ? -20.343 13.158 39.260 1.000 49.525  0 236 ARG A NE    1 ? ? 
ATOM   1830 C CZ    . ARG A 1 255 ? -19.842 12.881 38.039 1.000 50.566  0 236 ARG A CZ    1 ? ? 
ATOM   1831 N NH1   . ARG A 1 255 ? -18.777 12.111 37.878 1.000 51.838  0 236 ARG A NH1   1 ? ? 
ATOM   1832 N NH2   . ARG A 1 255 ? -20.452 13.362 36.964 1.000 46.979  0 236 ARG A NH2   1 ? ? 
ATOM   1833 N N     . LEU A 1 256 ? -15.977 14.297 44.406 1.000 23.888  0 237 LEU A N     1 ? ? 
ATOM   1834 C CA    . LEU A 1 256 ? -15.211 13.990 45.600 1.000 23.699  0 237 LEU A CA    1 ? ? 
ATOM   1835 C C     . LEU A 1 256 ? -15.217 15.205 46.527 1.000 25.174  0 237 LEU A C     1 ? ? 
ATOM   1836 O O     . LEU A 1 256 ? -15.583 15.092 47.699 1.000 24.619  0 237 LEU A O     1 ? ? 
ATOM   1837 C CB    . LEU A 1 256 ? -13.786 13.598 45.189 1.000 23.280  0 237 LEU A CB    1 ? ? 
ATOM   1838 C CG    . LEU A 1 256 ? -12.815 13.273 46.330 1.000 23.953  0 237 LEU A CG    1 ? ? 
ATOM   1839 C CD1   . LEU A 1 256 ? -13.079 11.892 46.906 1.000 23.731  0 237 LEU A CD1   1 ? ? 
ATOM   1840 C CD2   . LEU A 1 256 ? -11.364 13.396 45.880 1.000 23.325  0 237 LEU A CD2   1 ? ? 
ATOM   1841 N N     . LEU A 1 257 ? -14.851 16.378 45.990 1.000 24.887  0 238 LEU A N     1 ? ? 
ATOM   1842 C CA    . LEU A 1 257 ? -14.671 17.552 46.836 1.000 26.232  0 238 LEU A CA    1 ? ? 
ATOM   1843 C C     . LEU A 1 257 ? -16.010 18.033 47.391 1.000 27.420  0 238 LEU A C     1 ? ? 
ATOM   1844 O O     . LEU A 1 257 ? -16.095 18.456 48.547 1.000 27.091  0 238 LEU A O     1 ? ? 
ATOM   1845 C CB    . LEU A 1 257 ? -13.966 18.652 46.040 1.000 25.470  0 238 LEU A CB    1 ? ? 
ATOM   1846 C CG    . LEU A 1 257 ? -12.564 18.288 45.559 1.000 25.797  0 238 LEU A CG    1 ? ? 
ATOM   1847 C CD1   . LEU A 1 257 ? -11.974 19.396 44.709 1.000 25.438  0 238 LEU A CD1   1 ? ? 
ATOM   1848 C CD2   . LEU A 1 257 ? -11.647 17.987 46.729 1.000 25.282  0 238 LEU A CD2   1 ? ? 
ATOM   1849 N N     . LEU A 1 258 ? -17.066 17.926 46.578 1.000 28.947  0 239 LEU A N     1 ? ? 
ATOM   1850 C CA    . LEU A 1 258 ? -18.381 18.307 47.047 1.000 29.524  0 239 LEU A CA    1 ? ? 
ATOM   1851 C C     . LEU A 1 258 ? -18.815 17.414 48.199 1.000 32.561  0 239 LEU A C     1 ? ? 
ATOM   1852 O O     . LEU A 1 258 ? -19.344 17.916 49.191 1.000 34.376  0 239 LEU A O     1 ? ? 
ATOM   1853 C CB    . LEU A 1 258 ? -19.353 18.226 45.874 1.000 26.625  0 239 LEU A CB    1 ? ? 
ATOM   1854 C CG    . LEU A 1 258 ? -19.399 19.522 45.084 1.000 26.456  0 239 LEU A CG    1 ? ? 
ATOM   1855 C CD1   . LEU A 1 258 ? -20.087 19.275 43.757 1.000 25.560  0 239 LEU A CD1   1 ? ? 
ATOM   1856 C CD2   . LEU A 1 258 ? -20.105 20.587 45.906 1.000 25.490  0 239 LEU A CD2   1 ? ? 
ATOM   1857 N N     . ASN A 1 259 ? -18.570 16.104 48.067 1.000 34.797  0 240 ASN A N     1 ? ? 
ATOM   1858 C CA    . ASN A 1 259 ? -18.962 15.157 49.098 1.000 37.258  0 240 ASN A CA    1 ? ? 
ATOM   1859 C C     . ASN A 1 259 ? -18.218 15.465 50.398 1.000 34.669  0 240 ASN A C     1 ? ? 
ATOM   1860 O O     . ASN A 1 259 ? -18.751 15.316 51.499 1.000 33.129  0 240 ASN A O     1 ? ? 
ATOM   1861 C CB    . ASN A 1 259 ? -18.694 13.709 48.669 1.000 46.055  0 240 ASN A CB    1 ? ? 
ATOM   1862 C CG    . ASN A 1 259 ? -19.378 12.722 49.590 1.000 56.064  0 240 ASN A CG    1 ? ? 
ATOM   1863 O OD1   . ASN A 1 259 ? -20.583 12.517 49.472 1.000 61.091  0 240 ASN A OD1   1 ? ? 
ATOM   1864 N ND2   . ASN A 1 259 ? -18.652 12.150 50.543 1.000 58.401  0 240 ASN A ND2   1 ? ? 
ATOM   1865 N N     . ARG A 1 260 ? -16.978 15.940 50.287 1.000 32.386  0 241 ARG A N     1 ? ? 
ATOM   1866 C CA    . ARG A 1 260 ? -16.195 16.125 51.490 1.000 30.122  0 241 ARG A CA    1 ? ? 
ATOM   1867 C C     . ARG A 1 260 ? -16.671 17.336 52.295 1.000 29.988  0 241 ARG A C     1 ? ? 
ATOM   1868 O O     . ARG A 1 260 ? -16.183 17.548 53.403 1.000 29.561  0 241 ARG A O     1 ? ? 
ATOM   1869 C CB    . ARG A 1 260 ? -14.707 16.173 51.155 1.000 30.071  0 241 ARG A CB    1 ? ? 
ATOM   1870 C CG    . ARG A 1 260 ? -14.120 14.847 50.691 1.000 30.380  0 241 ARG A CG    1 ? ? 
ATOM   1871 C CD    . ARG A 1 260 ? -12.630 14.932 50.391 1.000 29.878  0 241 ARG A CD    1 ? ? 
ATOM   1872 N NE    . ARG A 1 260 ? -12.052 13.626 50.054 1.000 29.870  0 241 ARG A NE    1 ? ? 
ATOM   1873 C CZ    . ARG A 1 260 ? -10.768 13.322 49.752 1.000 32.882  0 241 ARG A CZ    1 ? ? 
ATOM   1874 N NH1   . ARG A 1 260 ? -10.439 12.076 49.489 1.000 30.390  0 241 ARG A NH1   1 ? ? 
ATOM   1875 N NH2   . ARG A 1 260 ? -9.782  14.206 49.733 1.000 33.053  0 241 ARG A NH2   1 ? ? 
ATOM   1876 N N     . PHE A 1 261 ? -17.643 18.095 51.766 1.000 29.256  0 242 PHE A N     1 ? ? 
ATOM   1877 C CA    . PHE A 1 261 ? -18.298 19.131 52.561 1.000 29.943  0 242 PHE A CA    1 ? ? 
ATOM   1878 C C     . PHE A 1 261 ? -19.239 18.472 53.567 1.000 33.980  0 242 PHE A C     1 ? ? 
ATOM   1879 O O     . PHE A 1 261 ? -19.348 18.917 54.713 1.000 36.192  0 242 PHE A O     1 ? ? 
ATOM   1880 C CB    . PHE A 1 261 ? -19.157 20.075 51.714 1.000 27.115  0 242 PHE A CB    1 ? ? 
ATOM   1881 C CG    . PHE A 1 261 ? -18.382 21.083 50.914 1.000 26.394  0 242 PHE A CG    1 ? ? 
ATOM   1882 C CD1   . PHE A 1 261 ? -17.476 21.929 51.536 1.000 27.027  0 242 PHE A CD1   1 ? ? 
ATOM   1883 C CD2   . PHE A 1 261 ? -18.528 21.146 49.536 1.000 25.290  0 242 PHE A CD2   1 ? ? 
ATOM   1884 C CE1   . PHE A 1 261 ? -16.743 22.835 50.795 1.000 27.061  0 242 PHE A CE1   1 ? ? 
ATOM   1885 C CE2   . PHE A 1 261 ? -17.796 22.054 48.797 1.000 24.154  0 242 PHE A CE2   1 ? ? 
ATOM   1886 C CZ    . PHE A 1 261 ? -16.914 22.893 49.430 1.000 26.244  0 242 PHE A CZ    1 ? ? 
ATOM   1887 N N     . THR A 1 262 ? -19.876 17.381 53.121 1.000 34.882  0 243 THR A N     1 ? ? 
ATOM   1888 C CA    . THR A 1 262 ? -21.063 16.825 53.747 1.000 36.680  0 243 THR A CA    1 ? ? 
ATOM   1889 C C     . THR A 1 262 ? -20.731 15.938 54.939 1.000 37.215  0 243 THR A C     1 ? ? 
ATOM   1890 O O     . THR A 1 262 ? -21.640 15.398 55.544 1.000 38.181  0 243 THR A O     1 ? ? 
ATOM   1891 C CB    . THR A 1 262 ? -21.832 15.919 52.777 1.000 37.516  0 243 THR A CB    1 ? ? 
ATOM   1892 O OG1   . THR A 1 262 ? -21.186 14.647 52.685 1.000 39.480  0 243 THR A OG1   1 ? ? 
ATOM   1893 C CG2   . THR A 1 262 ? -21.940 16.456 51.363 1.000 38.212  0 243 THR A CG2   1 ? ? 
ATOM   1894 N N     . MET A 1 263 ? -19.459 15.777 55.282 1.000 36.656  0 244 MET A N     1 ? ? 
ATOM   1895 C CA    . MET A 1 263 ? -19.126 14.844 56.338 1.000 37.544  0 244 MET A CA    1 ? ? 
ATOM   1896 C C     . MET A 1 263 ? -18.285 15.595 57.348 1.000 36.112  0 244 MET A C     1 ? ? 
ATOM   1897 O O     . MET A 1 263 ? -17.561 16.515 57.008 1.000 36.043  0 244 MET A O     1 ? ? 
ATOM   1898 C CB    . MET A 1 263 ? -18.295 13.688 55.784 1.000 40.679  0 244 MET A CB    1 ? ? 
ATOM   1899 C CG    . MET A 1 263 ? -17.091 14.184 55.021 1.000 41.872  0 244 MET A CG    1 ? ? 
ATOM   1900 S SD    . MET A 1 263 ? -16.359 12.924 53.975 1.000 47.025  0 244 MET A SD    1 ? ? 
ATOM   1901 C CE    . MET A 1 263 ? -17.838 12.468 53.086 1.000 41.575  0 244 MET A CE    1 ? ? 
ATOM   1902 N N     . THR A 1 264 ? -18.356 15.173 58.602 1.000 34.049  0 245 THR A N     1 ? ? 
ATOM   1903 C CA    . THR A 1 264 ? -17.446 15.714 59.595 1.000 35.108  0 245 THR A CA    1 ? ? 
ATOM   1904 C C     . THR A 1 264 ? -16.012 15.447 59.134 1.000 36.073  0 245 THR A C     1 ? ? 
ATOM   1905 O O     . THR A 1 264 ? -15.756 14.459 58.435 1.000 39.051  0 245 THR A O     1 ? ? 
ATOM   1906 C CB    . THR A 1 264 ? -17.769 15.092 60.958 1.000 37.261  0 245 THR A CB    1 ? ? 
ATOM   1907 O OG1   . THR A 1 264 ? -19.067 15.538 61.362 1.000 35.656  0 245 THR A OG1   1 ? ? 
ATOM   1908 C CG2   . THR A 1 264 ? -16.750 15.421 62.025 1.000 34.195  0 245 THR A CG2   1 ? ? 
ATOM   1909 N N     . HIS A 1 265 ? -15.074 16.324 59.535 1.000 34.585  0 246 HIS A N     1 ? ? 
ATOM   1910 C CA    . HIS A 1 265 ? -13.678 16.184 59.150 1.000 34.994  0 246 HIS A CA    1 ? ? 
ATOM   1911 C C     . HIS A 1 265 ? -13.259 14.722 59.355 1.000 36.192  0 246 HIS A C     1 ? ? 
ATOM   1912 O O     . HIS A 1 265 ? -13.606 14.049 60.339 1.000 36.548  0 246 HIS A O     1 ? ? 
ATOM   1913 C CB    . HIS A 1 265 ? -12.853 17.264 59.878 1.000 34.918  0 246 HIS A CB    1 ? ? 
ATOM   1914 C CG    . HIS A 1 265 ? -11.366 17.098 59.889 1.000 36.226  0 246 HIS A CG    1 ? ? 
ATOM   1915 N ND1   . HIS A 1 265 ? -10.559 17.653 58.920 1.000 36.405  0 246 HIS A ND1   1 ? ? 
ATOM   1916 C CD2   . HIS A 1 265 ? -10.522 16.500 60.762 1.000 37.081  0 246 HIS A CD2   1 ? ? 
ATOM   1917 C CE1   . HIS A 1 265 ? -9.295  17.374 59.158 1.000 36.376  0 246 HIS A CE1   1 ? ? 
ATOM   1918 N NE2   . HIS A 1 265 ? -9.245  16.670 60.287 1.000 37.250  0 246 HIS A NE2   1 ? ? 
ATOM   1919 N N     . ARG A 1 266 ? -12.556 14.205 58.354 1.000 34.989  0 247 ARG A N     1 ? ? 
ATOM   1920 C CA    . ARG A 1 266 ? -11.801 12.969 58.499 1.000 34.173  0 247 ARG A CA    1 ? ? 
ATOM   1921 C C     . ARG A 1 266 ? -10.321 13.305 58.525 1.000 32.602  0 247 ARG A C     1 ? ? 
ATOM   1922 O O     . ARG A 1 266 ? -9.817  13.836 57.550 1.000 34.844  0 247 ARG A O     1 ? ? 
ATOM   1923 C CB    . ARG A 1 266 ? -12.023 12.076 57.284 1.000 33.982  0 247 ARG A CB    1 ? ? 
ATOM   1924 C CG    . ARG A 1 266 ? -13.161 11.095 57.473 1.000 38.988  0 247 ARG A CG    1 ? ? 
ATOM   1925 C CD    . ARG A 1 266 ? -14.408 11.791 57.914 1.000 40.913  0 247 ARG A CD    1 ? ? 
ATOM   1926 N NE    . ARG A 1 266 ? -15.607 11.142 57.437 1.000 43.907  0 247 ARG A NE    1 ? ? 
ATOM   1927 C CZ    . ARG A 1 266 ? -16.757 11.162 58.084 1.000 43.961  0 247 ARG A CZ    1 ? ? 
ATOM   1928 N NH1   . ARG A 1 266 ? -17.802 10.579 57.533 1.000 47.200  0 247 ARG A NH1   1 ? ? 
ATOM   1929 N NH2   . ARG A 1 266 ? -16.863 11.722 59.282 1.000 41.779  0 247 ARG A NH2   1 ? ? 
ATOM   1930 N N     . ARG A 1 267 ? -9.624  12.967 59.608 1.000 28.472  0 248 ARG A N     1 ? ? 
ATOM   1931 C CA    . ARG A 1 267 ? -8.235  13.370 59.705 1.000 25.121  0 248 ARG A CA    1 ? ? 
ATOM   1932 C C     . ARG A 1 267 ? -7.414  12.812 58.536 1.000 23.944  0 248 ARG A C     1 ? ? 
ATOM   1933 O O     . ARG A 1 267 ? -7.678  11.722 58.027 1.000 22.612  0 248 ARG A O     1 ? ? 
ATOM   1934 C CB    . ARG A 1 267 ? -7.693  13.003 61.088 1.000 25.027  0 248 ARG A CB    1 ? ? 
ATOM   1935 C CG    . ARG A 1 267 ? -8.432  13.736 62.195 1.000 24.828  0 248 ARG A CG    1 ? ? 
ATOM   1936 C CD    . ARG A 1 267 ? -9.053  12.686 63.095 1.000 24.913  0 248 ARG A CD    1 ? ? 
ATOM   1937 N NE    . ARG A 1 267 ? -8.013  12.384 64.039 1.000 23.813  0 248 ARG A NE    1 ? ? 
ATOM   1938 C CZ    . ARG A 1 267 ? -7.960  11.303 64.794 1.000 24.817  0 248 ARG A CZ    1 ? ? 
ATOM   1939 N NH1   . ARG A 1 267 ? -6.927  11.165 65.607 1.000 25.978  0 248 ARG A NH1   1 ? ? 
ATOM   1940 N NH2   . ARG A 1 267 ? -8.928  10.392 64.757 1.000 22.985  0 248 ARG A NH2   1 ? ? 
ATOM   1941 N N     . PRO A 1 268 ? -6.410  13.579 58.057 1.000 23.786  0 249 PRO A N     1 ? ? 
ATOM   1942 C CA    . PRO A 1 268 ? -5.613  13.165 56.908 1.000 22.848  0 249 PRO A CA    1 ? ? 
ATOM   1943 C C     . PRO A 1 268 ? -4.761  11.940 57.219 1.000 22.170  0 249 PRO A C     1 ? ? 
ATOM   1944 O O     . PRO A 1 268 ? -4.323  11.738 58.352 1.000 20.191  0 249 PRO A O     1 ? ? 
ATOM   1945 C CB    . PRO A 1 268 ? -4.742  14.389 56.611 1.000 22.774  0 249 PRO A CB    1 ? ? 
ATOM   1946 C CG    . PRO A 1 268 ? -4.691  15.147 57.917 1.000 22.563  0 249 PRO A CG    1 ? ? 
ATOM   1947 C CD    . PRO A 1 268 ? -6.019  14.896 58.575 1.000 22.643  0 249 PRO A CD    1 ? ? 
ATOM   1948 N N     . THR A 1 269 ? -4.586  11.112 56.188 1.000 22.436  0 250 THR A N     1 ? ? 
ATOM   1949 C CA    . THR A 1 269 ? -3.703  9.961  56.212 1.000 22.601  0 250 THR A CA    1 ? ? 
ATOM   1950 C C     . THR A 1 269 ? -2.272  10.471 56.174 1.000 22.769  0 250 THR A C     1 ? ? 
ATOM   1951 O O     . THR A 1 269 ? -1.871  11.086 55.195 1.000 23.786  0 250 THR A O     1 ? ? 
ATOM   1952 C CB    . THR A 1 269 ? -3.954  9.084  54.979 1.000 22.671  0 250 THR A CB    1 ? ? 
ATOM   1953 O OG1   . THR A 1 269 ? -5.364  8.859  54.914 1.000 24.445  0 250 THR A OG1   1 ? ? 
ATOM   1954 C CG2   . THR A 1 269 ? -3.194  7.778  55.028 1.000 21.511  0 250 THR A CG2   1 ? ? 
ATOM   1955 N N     . ILE A 1 270 ? -1.535  10.243 57.257 1.000 23.352  0 251 ILE A N     1 ? ? 
ATOM   1956 C CA    . ILE A 1 270 ? -0.204  10.805 57.400 1.000 26.456  0 251 ILE A CA    1 ? ? 
ATOM   1957 C C     . ILE A 1 270 ? 0.800   9.790  56.877 1.000 28.415  0 251 ILE A C     1 ? ? 
ATOM   1958 O O     . ILE A 1 270 ? 0.753   8.624  57.267 1.000 29.299  0 251 ILE A O     1 ? ? 
ATOM   1959 C CB    . ILE A 1 270 ? 0.075   11.167 58.875 1.000 25.791  0 251 ILE A CB    1 ? ? 
ATOM   1960 C CG1   . ILE A 1 270 ? -1.021  12.044 59.483 1.000 26.061  0 251 ILE A CG1   1 ? ? 
ATOM   1961 C CG2   . ILE A 1 270 ? 1.456   11.757 59.051 1.000 25.359  0 251 ILE A CG2   1 ? ? 
ATOM   1962 C CD1   . ILE A 1 270 ? -1.208  13.369 58.830 1.000 26.654  0 251 ILE A CD1   1 ? ? 
ATOM   1963 N N     . GLU A 1 271 ? 1.694   10.247 55.994 1.000 29.782  0 252 GLU A N     1 ? ? 
ATOM   1964 C CA    . GLU A 1 271 ? 2.750   9.412  55.434 1.000 30.299  0 252 GLU A CA    1 ? ? 
ATOM   1965 C C     . GLU A 1 271 ? 4.119   9.965  55.815 1.000 29.519  0 252 GLU A C     1 ? ? 
ATOM   1966 O O     . GLU A 1 271 ? 4.247   11.096 56.266 1.000 30.582  0 252 GLU A O     1 ? ? 
ATOM   1967 C CB    . GLU A 1 271 ? 2.651   9.395  53.906 1.000 31.182  0 252 GLU A CB    1 ? ? 
ATOM   1968 C CG    . GLU A 1 271 ? 1.375   8.777  53.387 1.000 34.164  0 252 GLU A CG    1 ? ? 
ATOM   1969 C CD    . GLU A 1 271 ? 1.195   7.330  53.805 1.000 35.918  0 252 GLU A CD    1 ? ? 
ATOM   1970 O OE1   . GLU A 1 271 ? 0.111   6.787  53.590 1.000 36.054  0 252 GLU A OE1   1 ? ? 
ATOM   1971 O OE2   . GLU A 1 271 ? 2.164   6.745  54.334 1.000 37.664  0 252 GLU A OE2   1 ? ? 
ATOM   1972 N N     . LYS A 1 272 ? 5.154   9.134  55.673 1.000 31.074  0 253 LYS A N     1 ? ? 
ATOM   1973 C CA    . LYS A 1 272 ? 6.526   9.561  55.903 1.000 30.308  0 253 LYS A CA    1 ? ? 
ATOM   1974 C C     . LYS A 1 272 ? 6.924   10.467 54.742 1.000 28.301  0 253 LYS A C     1 ? ? 
ATOM   1975 O O     . LYS A 1 272 ? 6.579   10.170 53.599 1.000 30.014  0 253 LYS A O     1 ? ? 
ATOM   1976 C CB    . LYS A 1 272 ? 7.469   8.350  55.966 1.000 31.860  0 253 LYS A CB    1 ? ? 
ATOM   1977 C CG    . LYS A 1 272 ? 8.450   8.293  57.143 1.000 33.982  0 253 LYS A CG    1 ? ? 
ATOM   1978 C CD    . LYS A 1 272 ? 7.694   8.366  58.451 1.000 37.942  0 253 LYS A CD    1 ? ? 
ATOM   1979 C CE    . LYS A 1 272 ? 8.421   9.051  59.593 1.000 44.180  0 253 LYS A CE    1 ? ? 
ATOM   1980 N NZ    . LYS A 1 272 ? 7.494   9.417  60.694 1.000 43.159  0 253 LYS A NZ    1 ? ? 
ATOM   1981 N N     . ASP A 1 273 ? 7.589   11.575 55.076 1.000 26.194  0 254 ASP A N     1 ? ? 
ATOM   1982 C CA    . ASP A 1 273 ? 8.142   12.481 54.099 1.000 25.803  0 254 ASP A CA    1 ? ? 
ATOM   1983 C C     . ASP A 1 273 ? 9.358   11.833 53.431 1.000 26.260  0 254 ASP A C     1 ? ? 
ATOM   1984 O O     . ASP A 1 273 ? 9.954   10.900 53.979 1.000 25.895  0 254 ASP A O     1 ? ? 
ATOM   1985 C CB    . ASP A 1 273 ? 8.467   13.826 54.748 1.000 25.111  0 254 ASP A CB    1 ? ? 
ATOM   1986 C CG    . ASP A 1 273 ? 8.692   14.924 53.718 1.000 25.564  0 254 ASP A CG    1 ? ? 
ATOM   1987 O OD1   . ASP A 1 273 ? 8.247   14.767 52.572 1.000 26.749  0 254 ASP A OD1   1 ? ? 
ATOM   1988 O OD2   . ASP A 1 273 ? 9.332   15.918 54.048 1.000 26.004  0 254 ASP A OD2   1 ? ? 
ATOM   1989 N N     . VAL A 1 274 ? 9.708   12.351 52.245 1.000 24.393  0 255 VAL A N     1 ? ? 
ATOM   1990 C CA    . VAL A 1 274 ? 10.811  11.862 51.436 1.000 25.128  0 255 VAL A CA    1 ? ? 
ATOM   1991 C C     . VAL A 1 274 ? 12.166  12.121 52.114 1.000 25.061  0 255 VAL A C     1 ? ? 
ATOM   1992 O O     . VAL A 1 274 ? 12.422  13.197 52.664 1.000 23.744  0 255 VAL A O     1 ? ? 
ATOM   1993 C CB    . VAL A 1 274 ? 10.779  12.510 50.034 1.000 25.658  0 255 VAL A CB    1 ? ? 
ATOM   1994 C CG1   . VAL A 1 274 ? 9.509   12.231 49.306 1.000 25.713  0 255 VAL A CG1   1 ? ? 
ATOM   1995 C CG2   . VAL A 1 274 ? 10.953  14.019 50.092 1.000 25.054  0 255 VAL A CG2   1 ? ? 
ATOM   1996 N N     . ASP A 1 275 ? 13.062  11.135 52.014 1.000 23.934  0 256 ASP A N     1 ? ? 
ATOM   1997 C CA    . ASP A 1 275 ? 14.475  11.307 52.330 1.000 23.525  0 256 ASP A CA    1 ? ? 
ATOM   1998 C C     . ASP A 1 275 ? 15.241  11.481 51.017 1.000 22.483  0 256 ASP A C     1 ? ? 
ATOM   1999 O O     . ASP A 1 275 ? 15.308  10.555 50.201 1.000 20.890  0 256 ASP A O     1 ? ? 
ATOM   2000 C CB    . ASP A 1 275 ? 14.993  10.121 53.156 1.000 23.720  0 256 ASP A CB    1 ? ? 
ATOM   2001 C CG    . ASP A 1 275 ? 16.457  10.222 53.547 1.000 25.023  0 256 ASP A CG    1 ? ? 
ATOM   2002 O OD1   . ASP A 1 275 ? 17.075  11.248 53.217 1.000 24.531  0 256 ASP A OD1   1 ? ? 
ATOM   2003 O OD2   . ASP A 1 275 ? 16.967  9.277  54.194 1.000 27.257  0 256 ASP A OD2   1 ? ? 
ATOM   2004 N N     . LEU A 1 276 ? 15.802  12.675 50.799 1.000 22.239  0 257 LEU A N     1 ? ? 
ATOM   2005 C CA    . LEU A 1 276 ? 16.432  12.978 49.517 1.000 23.996  0 257 LEU A CA    1 ? ? 
ATOM   2006 C C     . LEU A 1 276 ? 17.945  12.777 49.548 1.000 24.883  0 257 LEU A C     1 ? ? 
ATOM   2007 O O     . LEU A 1 276 ? 18.605  13.084 48.558 1.000 23.064  0 257 LEU A O     1 ? ? 
ATOM   2008 C CB    . LEU A 1 276 ? 16.103  14.406 49.070 1.000 25.156  0 257 LEU A CB    1 ? ? 
ATOM   2009 C CG    . LEU A 1 276 ? 14.637  14.696 48.741 1.000 26.929  0 257 LEU A CG    1 ? ? 
ATOM   2010 C CD1   . LEU A 1 276 ? 14.477  16.125 48.253 1.000 25.374  0 257 LEU A CD1   1 ? ? 
ATOM   2011 C CD2   . LEU A 1 276 ? 14.136  13.742 47.668 1.000 24.247  0 257 LEU A CD2   1 ? ? 
ATOM   2012 N N     . GLY A 1 277 ? 18.476  12.303 50.685 1.000 25.797  0 258 GLY A N     1 ? ? 
ATOM   2013 C CA    . GLY A 1 277 ? 19.842  11.808 50.774 1.000 27.707  0 258 GLY A CA    1 ? ? 
ATOM   2014 C C     . GLY A 1 277 ? 20.887  12.919 50.808 1.000 29.371  0 258 GLY A C     1 ? ? 
ATOM   2015 O O     . GLY A 1 277 ? 20.603  14.039 51.229 1.000 31.301  0 258 GLY A O     1 ? ? 
ATOM   2016 N N     . ALA A 1 278 ? 22.103  12.597 50.338 1.000 28.668  0 259 ALA A N     1 ? ? 
ATOM   2017 C CA    . ALA A 1 278 ? 23.220  13.534 50.354 1.000 27.117  0 259 ALA A CA    1 ? ? 
ATOM   2018 C C     . ALA A 1 278 ? 24.203  13.211 49.234 1.000 26.222  0 259 ALA A C     1 ? ? 
ATOM   2019 O O     . ALA A 1 278 ? 24.189  12.114 48.678 1.000 26.325  0 259 ALA A O     1 ? ? 
ATOM   2020 C CB    . ALA A 1 278 ? 23.909  13.554 51.702 1.000 24.157  0 259 ALA A CB    1 ? ? 
ATOM   2021 N N     . GLY A 1 279 ? 25.013  14.217 48.887 1.000 24.284  0 260 GLY A N     1 ? ? 
ATOM   2022 C CA    . GLY A 1 279 ? 26.205  14.012 48.088 1.000 25.681  0 260 GLY A CA    1 ? ? 
ATOM   2023 C C     . GLY A 1 279 ? 25.971  14.193 46.592 1.000 25.328  0 260 GLY A C     1 ? ? 
ATOM   2024 O O     . GLY A 1 279 ? 24.822  14.284 46.138 1.000 24.024  0 260 GLY A O     1 ? ? 
ATOM   2025 N N     . THR A 1 280 ? 27.094  14.242 45.860 1.000 25.510  0 261 THR A N     1 ? ? 
ATOM   2026 C CA    . THR A 1 280 ? 27.075  14.459 44.423 1.000 24.860  0 261 THR A CA    1 ? ? 
ATOM   2027 C C     . THR A 1 280 ? 26.660  13.180 43.703 1.000 24.767  0 261 THR A C     1 ? ? 
ATOM   2028 O O     . THR A 1 280 ? 26.529  12.105 44.282 1.000 24.367  0 261 THR A O     1 ? ? 
ATOM   2029 C CB    . THR A 1 280 ? 28.434  14.926 43.878 1.000 23.427  0 261 THR A CB    1 ? ? 
ATOM   2030 O OG1   . THR A 1 280 ? 29.428  13.932 44.133 1.000 21.567  0 261 THR A OG1   1 ? ? 
ATOM   2031 C CG2   . THR A 1 280 ? 28.899  16.224 44.493 1.000 22.417  0 261 THR A CG2   1 ? ? 
ATOM   2032 N N     . ARG A 1 281 ? 26.413  13.306 42.409 1.000 26.364  0 262 ARG A N     1 ? ? 
ATOM   2033 C CA    . ARG A 1 281 ? 26.221  12.136 41.582 1.000 28.465  0 262 ARG A CA    1 ? ? 
ATOM   2034 C C     . ARG A 1 281 ? 27.155  12.228 40.373 1.000 28.717  0 262 ARG A C     1 ? ? 
ATOM   2035 O O     . ARG A 1 281 ? 27.673  13.301 40.022 1.000 29.909  0 262 ARG A O     1 ? ? 
ATOM   2036 C CB    . ARG A 1 281 ? 24.933  12.254 40.784 1.000 29.812  0 262 ARG A CB    1 ? ? 
ATOM   2037 C CG    . ARG A 1 281 ? 23.562  12.284 41.407 1.000 30.528  0 262 ARG A CG    1 ? ? 
ATOM   2038 C CD    . ARG A 1 281 ? 22.844  12.794 40.124 1.000 32.207  0 262 ARG A CD    1 ? ? 
ATOM   2039 N NE    . ARG A 1 281 ? 22.650  11.650 39.222 1.000 32.562  0 262 ARG A NE    1 ? ? 
ATOM   2040 C CZ    . ARG A 1 281 ? 21.507  11.307 38.625 1.000 30.630  0 262 ARG A CZ    1 ? ? 
ATOM   2041 N NH1   . ARG A 1 281 ? 20.477  12.121 38.719 1.000 29.755  0 262 ARG A NH1   1 ? ? 
ATOM   2042 N NH2   . ARG A 1 281 ? 21.414  10.195 37.910 1.000 28.489  0 262 ARG A NH2   1 ? ? 
ATOM   2043 N N     . GLU B 1 26  ? -14.493 39.359 8.507  1.000 31.044  0 7   GLU B N     1 ? ? 
ATOM   2044 C CA    . GLU B 1 26  ? -13.495 40.443 8.313  1.000 31.759  0 7   GLU B CA    1 ? ? 
ATOM   2045 C C     . GLU B 1 26  ? -12.940 40.914 9.658  1.000 31.923  0 7   GLU B C     1 ? ? 
ATOM   2046 O O     . GLU B 1 26  ? -13.641 40.943 10.670 1.000 36.800  0 7   GLU B O     1 ? ? 
ATOM   2047 C CB    . GLU B 1 26  ? -14.085 41.598 7.498  1.000 32.864  0 7   GLU B CB    1 ? ? 
ATOM   2048 C CG    . GLU B 1 26  ? -13.077 42.669 7.160  1.000 32.537  0 7   GLU B CG    1 ? ? 
ATOM   2049 C CD    . GLU B 1 26  ? -13.732 43.957 6.746  1.000 35.037  0 7   GLU B CD    1 ? ? 
ATOM   2050 O OE1   . GLU B 1 26  ? -14.134 44.065 5.570  1.000 33.463  0 7   GLU B OE1   1 ? ? 
ATOM   2051 O OE2   . GLU B 1 26  ? -14.044 44.720 7.664  1.000 36.589  0 7   GLU B OE2   1 ? ? 
ATOM   2052 N N     . THR B 1 27  ? -11.642 41.220 9.655  1.000 28.886  0 8   THR B N     1 ? ? 
ATOM   2053 C CA    . THR B 1 27  ? -10.917 41.544 10.867 1.000 27.040  0 8   THR B CA    1 ? ? 
ATOM   2054 C C     . THR B 1 27  ? -10.971 43.049 11.133 1.000 26.532  0 8   THR B C     1 ? ? 
ATOM   2055 O O     . THR B 1 27  ? -11.223 43.853 10.246 1.000 26.658  0 8   THR B O     1 ? ? 
ATOM   2056 C CB    . THR B 1 27  ? -9.468  41.047 10.765 1.000 27.005  0 8   THR B CB    1 ? ? 
ATOM   2057 O OG1   . THR B 1 27  ? -8.853  41.822 9.737  1.000 26.695  0 8   THR B OG1   1 ? ? 
ATOM   2058 C CG2   . THR B 1 27  ? -9.357  39.571 10.450 1.000 25.224  0 8   THR B CG2   1 ? ? 
ATOM   2059 N N     . LEU B 1 28  ? -10.709 43.425 12.386 1.000 25.904  0 9   LEU B N     1 ? ? 
ATOM   2060 C CA    . LEU B 1 28  ? -10.626 44.824 12.769 1.000 25.745  0 9   LEU B CA    1 ? ? 
ATOM   2061 C C     . LEU B 1 28  ? -9.512  45.541 12.010 1.000 25.207  0 9   LEU B C     1 ? ? 
ATOM   2062 O O     . LEU B 1 28  ? -9.660  46.678 11.571 1.000 24.414  0 9   LEU B O     1 ? ? 
ATOM   2063 C CB    . LEU B 1 28  ? -10.363 44.903 14.268 1.000 24.983  0 9   LEU B CB    1 ? ? 
ATOM   2064 C CG    . LEU B 1 28  ? -11.614 45.053 15.121 1.000 24.885  0 9   LEU B CG    1 ? ? 
ATOM   2065 C CD1   . LEU B 1 28  ? -11.312 44.742 16.572 1.000 24.215  0 9   LEU B CD1   1 ? ? 
ATOM   2066 C CD2   . LEU B 1 28  ? -12.196 46.430 14.994 1.000 25.250  0 9   LEU B CD2   1 ? ? 
ATOM   2067 N N     . GLY B 1 29  ? -8.398  44.842 11.807 1.000 26.171  0 10  GLY B N     1 ? ? 
ATOM   2068 C CA    . GLY B 1 29  ? -7.282  45.388 11.055 1.000 25.173  0 10  GLY B CA    1 ? ? 
ATOM   2069 C C     . GLY B 1 29  ? -7.670  45.740 9.620  1.000 24.964  0 10  GLY B C     1 ? ? 
ATOM   2070 O O     . GLY B 1 29  ? -7.222  46.746 9.075  1.000 24.786  0 10  GLY B O     1 ? ? 
ATOM   2071 N N     . GLU B 1 30  ? -8.513  44.896 9.015  1.000 23.771  0 11  GLU B N     1 ? ? 
ATOM   2072 C CA    . GLU B 1 30  ? -8.873  45.106 7.625  1.000 23.591  0 11  GLU B CA    1 ? ? 
ATOM   2073 C C     . GLU B 1 30  ? -9.704  46.373 7.501  1.000 24.251  0 11  GLU B C     1 ? ? 
ATOM   2074 O O     . GLU B 1 30  ? -9.552  47.120 6.544  1.000 24.555  0 11  GLU B O     1 ? ? 
ATOM   2075 C CB    . GLU B 1 30  ? -9.620  43.911 7.046  1.000 23.223  0 11  GLU B CB    1 ? ? 
ATOM   2076 C CG    . GLU B 1 30  ? -8.718  42.805 6.553  1.000 22.858  0 11  GLU B CG    1 ? ? 
ATOM   2077 C CD    . GLU B 1 30  ? -9.440  41.487 6.319  1.000 23.261  0 11  GLU B CD    1 ? ? 
ATOM   2078 O OE1   . GLU B 1 30  ? -9.831  40.826 7.319  1.000 20.911  0 11  GLU B OE1   1 ? ? 
ATOM   2079 O OE2   . GLU B 1 30  ? -9.559  41.094 5.127  1.000 24.853  0 11  GLU B OE2   1 ? ? 
ATOM   2080 N N     . LYS B 1 31  ? -10.537 46.624 8.505  1.000 25.122  0 12  LYS B N     1 ? ? 
ATOM   2081 C CA    . LYS B 1 31  ? -11.369 47.816 8.515  1.000 27.018  0 12  LYS B CA    1 ? ? 
ATOM   2082 C C     . LYS B 1 31  ? -10.477 49.055 8.640  1.000 26.800  0 12  LYS B C     1 ? ? 
ATOM   2083 O O     . LYS B 1 31  ? -10.670 50.055 7.949  1.000 27.537  0 12  LYS B O     1 ? ? 
ATOM   2084 C CB    . LYS B 1 31  ? -12.408 47.699 9.634  1.000 28.357  0 12  LYS B CB    1 ? ? 
ATOM   2085 C CG    . LYS B 1 31  ? -13.303 46.459 9.553  1.000 28.583  0 12  LYS B CG    1 ? ? 
ATOM   2086 C CD    . LYS B 1 31  ? -14.080 46.239 10.840 1.000 28.201  0 12  LYS B CD    1 ? ? 
ATOM   2087 C CE    . LYS B 1 31  ? -14.683 44.895 11.200 1.000 29.628  0 12  LYS B CE    1 ? ? 
ATOM   2088 N NZ    . LYS B 1 31  ? -15.835 44.421 10.415 1.000 30.586  0 12  LYS B NZ    1 ? ? 
ATOM   2089 N N     . TRP B 1 32  ? -9.489  48.983 9.532  1.000 25.896  0 13  TRP B N     1 ? ? 
ATOM   2090 C CA    . TRP B 1 32  ? -8.527  50.060 9.707  1.000 26.668  0 13  TRP B CA    1 ? ? 
ATOM   2091 C C     . TRP B 1 32  ? -7.836  50.381 8.375  1.000 27.523  0 13  TRP B C     1 ? ? 
ATOM   2092 O O     . TRP B 1 32  ? -7.660  51.542 8.024  1.000 26.527  0 13  TRP B O     1 ? ? 
ATOM   2093 C CB    . TRP B 1 32  ? -7.514  49.688 10.804 1.000 25.686  0 13  TRP B CB    1 ? ? 
ATOM   2094 C CG    . TRP B 1 32  ? -6.246  50.476 10.736 1.000 22.870  0 13  TRP B CG    1 ? ? 
ATOM   2095 C CD1   . TRP B 1 32  ? -6.040  51.710 11.264 1.000 21.963  0 13  TRP B CD1   1 ? ? 
ATOM   2096 C CD2   . TRP B 1 32  ? -5.035  50.118 10.054 1.000 22.965  0 13  TRP B CD2   1 ? ? 
ATOM   2097 N NE1   . TRP B 1 32  ? -4.775  52.138 10.977 1.000 21.192  0 13  TRP B NE1   1 ? ? 
ATOM   2098 C CE2   . TRP B 1 32  ? -4.133  51.184 10.236 1.000 22.341  0 13  TRP B CE2   1 ? ? 
ATOM   2099 C CE3   . TRP B 1 32  ? -4.617  48.998 9.322  1.000 24.007  0 13  TRP B CE3   1 ? ? 
ATOM   2100 C CZ2   . TRP B 1 32  ? -2.836  51.156 9.716  1.000 22.011  0 13  TRP B CZ2   1 ? ? 
ATOM   2101 C CZ3   . TRP B 1 32  ? -3.344  48.979 8.789  1.000 21.603  0 13  TRP B CZ3   1 ? ? 
ATOM   2102 C CH2   . TRP B 1 32  ? -2.475  50.053 8.972  1.000 21.160  0 13  TRP B CH2   1 ? ? 
ATOM   2103 N N     . LYS B 1 33  ? -7.398  49.343 7.653  1.000 27.190  0 14  LYS B N     1 ? ? 
ATOM   2104 C CA    . LYS B 1 33  ? -6.691  49.531 6.398  1.000 28.901  0 14  LYS B CA    1 ? ? 
ATOM   2105 C C     . LYS B 1 33  ? -7.557  50.291 5.402  1.000 32.281  0 14  LYS B C     1 ? ? 
ATOM   2106 O O     . LYS B 1 33  ? -7.083  51.226 4.763  1.000 32.921  0 14  LYS B O     1 ? ? 
ATOM   2107 C CB    . LYS B 1 33  ? -6.300  48.166 5.833  1.000 28.104  0 14  LYS B CB    1 ? ? 
ATOM   2108 C CG    . LYS B 1 33  ? -5.434  48.211 4.581  1.000 26.441  0 14  LYS B CG    1 ? ? 
ATOM   2109 C CD    . LYS B 1 33  ? -4.113  48.894 4.813  1.000 24.907  0 14  LYS B CD    1 ? ? 
ATOM   2110 C CE    . LYS B 1 33  ? -2.991  48.252 4.024  1.000 23.410  0 14  LYS B CE    1 ? ? 
ATOM   2111 N NZ    . LYS B 1 33  ? -1.736  49.031 4.179  1.000 25.541  0 14  LYS B NZ    1 ? ? 
ATOM   2112 N N     . LYS B 1 34  ? -8.829  49.900 5.300  1.000 34.614  0 15  LYS B N     1 ? ? 
ATOM   2113 C CA    . LYS B 1 34  ? -9.743  50.522 4.362  1.000 36.499  0 15  LYS B CA    1 ? ? 
ATOM   2114 C C     . LYS B 1 34  ? -9.938  51.998 4.682  1.000 37.268  0 15  LYS B C     1 ? ? 
ATOM   2115 O O     . LYS B 1 34  ? -9.929  52.820 3.779  1.000 41.217  0 15  LYS B O     1 ? ? 
ATOM   2116 C CB    . LYS B 1 34  ? -11.091 49.809 4.429  1.000 38.810  0 15  LYS B CB    1 ? ? 
ATOM   2117 C CG    . LYS B 1 34  ? -11.137 48.482 3.694  1.000 41.543  0 15  LYS B CG    1 ? ? 
ATOM   2118 C CD    . LYS B 1 34  ? -12.405 47.726 4.000  1.000 45.775  0 15  LYS B CD    1 ? ? 
ATOM   2119 C CE    . LYS B 1 34  ? -12.593 46.611 3.000  1.000 43.598  0 15  LYS B CE    1 ? ? 
ATOM   2120 N NZ    . LYS B 1 34  ? -12.001 45.399 3.601  1.000 41.074  0 15  LYS B NZ    1 ? ? 
ATOM   2121 N N     . LYS B 1 35  ? -10.187 52.309 5.960  1.000 36.588  0 16  LYS B N     1 ? ? 
ATOM   2122 C CA    . LYS B 1 35  ? -10.282 53.683 6.439  1.000 34.403  0 16  LYS B CA    1 ? ? 
ATOM   2123 C C     . LYS B 1 35  ? -8.988  54.434 6.130  1.000 33.318  0 16  LYS B C     1 ? ? 
ATOM   2124 O O     . LYS B 1 35  ? -9.040  55.596 5.757  1.000 31.151  0 16  LYS B O     1 ? ? 
ATOM   2125 C CB    . LYS B 1 35  ? -10.588 53.720 7.941  1.000 34.425  0 16  LYS B CB    1 ? ? 
ATOM   2126 C CG    . LYS B 1 35  ? -11.997 53.280 8.316  1.000 36.073  0 16  LYS B CG    1 ? ? 
ATOM   2127 C CD    . LYS B 1 35  ? -12.381 53.700 9.699  1.000 35.309  0 16  LYS B CD    1 ? ? 
ATOM   2128 C CE    . LYS B 1 35  ? -13.827 53.419 10.045 1.000 38.280  0 16  LYS B CE    1 ? ? 
ATOM   2129 N NZ    . LYS B 1 35  ? -14.142 53.929 11.399 1.000 41.681  0 16  LYS B NZ    1 ? ? 
ATOM   2130 N N     . LEU B 1 36  ? -7.838  53.763 6.286  1.000 32.697  0 17  LEU B N     1 ? ? 
ATOM   2131 C CA    . LEU B 1 36  ? -6.567  54.420 6.041  1.000 31.133  0 17  LEU B CA    1 ? ? 
ATOM   2132 C C     . LEU B 1 36  ? -6.414  54.751 4.557  1.000 33.886  0 17  LEU B C     1 ? ? 
ATOM   2133 O O     . LEU B 1 36  ? -6.017  55.852 4.191  1.000 36.698  0 17  LEU B O     1 ? ? 
ATOM   2134 C CB    . LEU B 1 36  ? -5.423  53.526 6.523  1.000 27.931  0 17  LEU B CB    1 ? ? 
ATOM   2135 C CG    . LEU B 1 36  ? -4.023  54.096 6.291  1.000 25.573  0 17  LEU B CG    1 ? ? 
ATOM   2136 C CD1   . LEU B 1 36  ? -3.693  55.199 7.272  1.000 25.908  0 17  LEU B CD1   1 ? ? 
ATOM   2137 C CD2   . LEU B 1 36  ? -2.967  53.016 6.306  1.000 23.718  0 17  LEU B CD2   1 ? ? 
ATOM   2138 N N     . ASN B 1 37  ? -6.746  53.798 3.685  1.000 33.234  0 18  ASN B N     1 ? ? 
ATOM   2139 C CA    . ASN B 1 37  ? -6.613  53.987 2.253  1.000 31.942  0 18  ASN B CA    1 ? ? 
ATOM   2140 C C     . ASN B 1 37  ? -7.526  55.085 1.721  1.000 32.961  0 18  ASN B C     1 ? ? 
ATOM   2141 O O     . ASN B 1 37  ? -7.287  55.572 0.630  1.000 31.580  0 18  ASN B O     1 ? ? 
ATOM   2142 C CB    . ASN B 1 37  ? -6.916  52.695 1.501  1.000 30.504  0 18  ASN B CB    1 ? ? 
ATOM   2143 C CG    . ASN B 1 37  ? -5.763  51.716 1.564  1.000 29.173  0 18  ASN B CG    1 ? ? 
ATOM   2144 O OD1   . ASN B 1 37  ? -4.611  52.112 1.668  1.000 29.872  0 18  ASN B OD1   1 ? ? 
ATOM   2145 N ND2   . ASN B 1 37  ? -6.035  50.427 1.473  1.000 27.127  0 18  ASN B ND2   1 ? ? 
ATOM   2146 N N     . GLN B 1 38  ? -8.569  55.461 2.461  1.000 35.250  0 19  GLN B N     1 ? ? 
ATOM   2147 C CA    . GLN B 1 38  ? -9.437  56.471 1.879  1.000 39.067  0 19  GLN B CA    1 ? ? 
ATOM   2148 C C     . GLN B 1 38  ? -9.129  57.866 2.415  1.000 39.749  0 19  GLN B C     1 ? ? 
ATOM   2149 O O     . GLN B 1 38  ? -9.845  58.805 2.097  1.000 44.325  0 19  GLN B O     1 ? ? 
ATOM   2150 C CB    . GLN B 1 38  ? -10.918 56.101 1.927  1.000 41.766  0 19  GLN B CB    1 ? ? 
ATOM   2151 C CG    . GLN B 1 38  ? -11.445 55.810 3.310  1.000 48.042  0 19  GLN B CG    1 ? ? 
ATOM   2152 C CD    . GLN B 1 38  ? -12.895 55.399 3.279  1.000 51.472  0 19  GLN B CD    1 ? ? 
ATOM   2153 O OE1   . GLN B 1 38  ? -13.757 56.131 2.791  1.000 52.469  0 19  GLN B OE1   1 ? ? 
ATOM   2154 N NE2   . GLN B 1 38  ? -13.174 54.221 3.824  1.000 51.794  0 19  GLN B NE2   1 ? ? 
ATOM   2155 N N     . LEU B 1 39  ? -8.085  57.995 3.233  1.000 40.583  0 20  LEU B N     1 ? ? 
ATOM   2156 C CA    . LEU B 1 39  ? -7.649  59.304 3.685  1.000 41.058  0 20  LEU B CA    1 ? ? 
ATOM   2157 C C     . LEU B 1 39  ? -6.967  60.054 2.543  1.000 42.740  0 20  LEU B C     1 ? ? 
ATOM   2158 O O     . LEU B 1 39  ? -6.277  59.479 1.696  1.000 43.861  0 20  LEU B O     1 ? ? 
ATOM   2159 C CB    . LEU B 1 39  ? -6.660  59.160 4.843  1.000 39.064  0 20  LEU B CB    1 ? ? 
ATOM   2160 C CG    . LEU B 1 39  ? -7.166  58.612 6.169  1.000 38.310  0 20  LEU B CG    1 ? ? 
ATOM   2161 C CD1   . LEU B 1 39  ? -5.999  58.692 7.151  1.000 36.979  0 20  LEU B CD1   1 ? ? 
ATOM   2162 C CD2   . LEU B 1 39  ? -8.383  59.388 6.678  1.000 39.598  0 20  LEU B CD2   1 ? ? 
ATOM   2163 N N     . SER B 1 40  ? -7.129  61.374 2.575  1.000 45.768  0 21  SER B N     1 ? ? 
ATOM   2164 C CA    . SER B 1 40  ? -6.379  62.250 1.701  1.000 47.465  0 21  SER B CA    1 ? ? 
ATOM   2165 C C     . SER B 1 40  ? -4.940  62.274 2.187  1.000 49.612  0 21  SER B C     1 ? ? 
ATOM   2166 O O     . SER B 1 40  ? -4.683  62.038 3.359  1.000 51.761  0 21  SER B O     1 ? ? 
ATOM   2167 C CB    . SER B 1 40  ? -6.965  63.628 1.708  1.000 46.424  0 21  SER B CB    1 ? ? 
ATOM   2168 O OG    . SER B 1 40  ? -6.807  64.244 2.965  1.000 43.579  0 21  SER B OG    1 ? ? 
ATOM   2169 N N     . ARG B 1 41  ? -4.011  62.636 1.309  1.000 51.126  0 22  ARG B N     1 ? ? 
ATOM   2170 C CA    . ARG B 1 41  ? -2.634  62.762 1.750  1.000 53.483  0 22  ARG B CA    1 ? ? 
ATOM   2171 C C     . ARG B 1 41  ? -2.523  63.726 2.929  1.000 52.798  0 22  ARG B C     1 ? ? 
ATOM   2172 O O     . ARG B 1 41  ? -1.626  63.547 3.744  1.000 56.854  0 22  ARG B O     1 ? ? 
ATOM   2173 C CB    . ARG B 1 41  ? -1.722  63.134 0.581  1.000 54.706  0 22  ARG B CB    1 ? ? 
ATOM   2174 C CG    . ARG B 1 41  ? -1.109  64.526 0.629  1.000 57.091  0 22  ARG B CG    1 ? ? 
ATOM   2175 C CD    . ARG B 1 41  ? -0.534  64.758 -0.757 1.000 60.907  0 22  ARG B CD    1 ? ? 
ATOM   2176 N NE    . ARG B 1 41  ? 0.093   63.517 -1.198 1.000 61.844  0 22  ARG B NE    1 ? ? 
ATOM   2177 C CZ    . ARG B 1 41  ? 1.219   63.433 -1.895 1.000 60.840  0 22  ARG B CZ    1 ? ? 
ATOM   2178 N NH1   . ARG B 1 41  ? 1.701   62.246 -2.225 1.000 59.135  0 22  ARG B NH1   1 ? ? 
ATOM   2179 N NH2   . ARG B 1 41  ? 1.860   64.533 -2.246 1.000 58.550  0 22  ARG B NH2   1 ? ? 
ATOM   2180 N N     . LYS B 1 42  ? -3.406  64.735 2.994  1.000 47.987  0 23  LYS B N     1 ? ? 
ATOM   2181 C CA    . LYS B 1 42  ? -3.338  65.695 4.081  1.000 46.087  0 23  LYS B CA    1 ? ? 
ATOM   2182 C C     . LYS B 1 42  ? -3.780  65.030 5.385  1.000 43.263  0 23  LYS B C     1 ? ? 
ATOM   2183 O O     . LYS B 1 42  ? -3.169  65.282 6.413  1.000 39.797  0 23  LYS B O     1 ? ? 
ATOM   2184 C CB    . LYS B 1 42  ? -4.126  66.972 3.795  1.000 46.748  0 23  LYS B CB    1 ? ? 
ATOM   2185 C CG    . LYS B 1 42  ? -4.280  67.902 4.984  1.000 52.149  0 23  LYS B CG    1 ? ? 
ATOM   2186 C CD    . LYS B 1 42  ? -5.541  68.714 4.857  1.000 54.201  0 23  LYS B CD    1 ? ? 
ATOM   2187 C CE    . LYS B 1 42  ? -5.888  69.411 6.153  1.000 60.861  0 23  LYS B CE    1 ? ? 
ATOM   2188 N NZ    . LYS B 1 42  ? -6.720  70.616 5.924  1.000 64.502  0 23  LYS B NZ    1 ? ? 
ATOM   2189 N N     . GLU B 1 43  ? -4.910  64.304 5.348  1.000 45.145  0 24  GLU B N     1 ? ? 
ATOM   2190 C CA    . GLU B 1 43  ? -5.452  63.569 6.485  1.000 43.440  0 24  GLU B CA    1 ? ? 
ATOM   2191 C C     . GLU B 1 43  ? -4.472  62.488 6.947  1.000 40.127  0 24  GLU B C     1 ? ? 
ATOM   2192 O O     . GLU B 1 43  ? -4.260  62.298 8.147  1.000 38.385  0 24  GLU B O     1 ? ? 
ATOM   2193 C CB    . GLU B 1 43  ? -6.792  62.941 6.111  1.000 44.334  0 24  GLU B CB    1 ? ? 
ATOM   2194 C CG    . GLU B 1 43  ? -7.918  63.948 6.022  1.000 48.956  0 24  GLU B CG    1 ? ? 
ATOM   2195 C CD    . GLU B 1 43  ? -9.104  63.575 5.145  1.000 55.422  0 24  GLU B CD    1 ? ? 
ATOM   2196 O OE1   . GLU B 1 43  ? -9.021  62.566 4.389  1.000 52.589  0 24  GLU B OE1   1 ? ? 
ATOM   2197 O OE2   . GLU B 1 43  ? -10.123 64.291 5.229  1.000 59.923  0 24  GLU B OE2   1 ? ? 
ATOM   2198 N N     . PHE B 1 44  ? -3.878  61.778 5.987  1.000 34.841  0 25  PHE B N     1 ? ? 
ATOM   2199 C CA    . PHE B 1 44  ? -2.849  60.790 6.261  1.000 33.458  0 25  PHE B CA    1 ? ? 
ATOM   2200 C C     . PHE B 1 44  ? -1.667  61.379 7.031  1.000 35.029  0 25  PHE B C     1 ? ? 
ATOM   2201 O O     . PHE B 1 44  ? -1.240  60.828 8.033  1.000 34.238  0 25  PHE B O     1 ? ? 
ATOM   2202 C CB    . PHE B 1 44  ? -2.317  60.242 4.941  1.000 30.278  0 25  PHE B CB    1 ? ? 
ATOM   2203 C CG    . PHE B 1 44  ? -1.312  59.134 5.072  1.000 27.593  0 25  PHE B CG    1 ? ? 
ATOM   2204 C CD1   . PHE B 1 44  ? 0.035   59.386 5.193  1.000 25.957  0 25  PHE B CD1   1 ? ? 
ATOM   2205 C CD2   . PHE B 1 44  ? -1.722  57.819 5.062  1.000 26.595  0 25  PHE B CD2   1 ? ? 
ATOM   2206 C CE1   . PHE B 1 44  ? 0.949   58.346 5.304  1.000 25.894  0 25  PHE B CE1   1 ? ? 
ATOM   2207 C CE2   . PHE B 1 44  ? -0.802  56.786 5.144  1.000 24.814  0 25  PHE B CE2   1 ? ? 
ATOM   2208 C CZ    . PHE B 1 44  ? 0.536   57.051 5.252  1.000 24.349  0 25  PHE B CZ    1 ? ? 
ATOM   2209 N N     . ASP B 1 45  ? -1.154  62.515 6.560  1.000 35.901  0 26  ASP B N     1 ? ? 
ATOM   2210 C CA    . ASP B 1 45  ? 0.042   63.102 7.138  1.000 36.362  0 26  ASP B CA    1 ? ? 
ATOM   2211 C C     . ASP B 1 45  ? -0.227  63.517 8.577  1.000 34.368  0 26  ASP B C     1 ? ? 
ATOM   2212 O O     . ASP B 1 45  ? 0.673   63.444 9.404  1.000 32.435  0 26  ASP B O     1 ? ? 
ATOM   2213 C CB    . ASP B 1 45  ? 0.584   64.219 6.245  1.000 38.588  0 26  ASP B CB    1 ? ? 
ATOM   2214 C CG    . ASP B 1 45  ? 1.343   63.655 5.052  1.000 44.365  0 26  ASP B CG    1 ? ? 
ATOM   2215 O OD1   . ASP B 1 45  ? 1.970   62.568 5.214  1.000 44.426  0 26  ASP B OD1   1 ? ? 
ATOM   2216 O OD2   . ASP B 1 45  ? 1.306   64.282 3.971  1.000 45.705  0 26  ASP B OD2   1 ? ? 
ATOM   2217 N N     . LEU B 1 46  ? -1.472  63.910 8.876  1.000 34.933  0 27  LEU B N     1 ? ? 
ATOM   2218 C CA    . LEU B 1 46  ? -1.845  64.196 10.253 1.000 38.273  0 27  LEU B CA    1 ? ? 
ATOM   2219 C C     . LEU B 1 46  ? -1.925  62.884 11.031 1.000 37.653  0 27  LEU B C     1 ? ? 
ATOM   2220 O O     . LEU B 1 46  ? -1.219  62.663 12.023 1.000 34.864  0 27  LEU B O     1 ? ? 
ATOM   2221 C CB    . LEU B 1 46  ? -3.166  64.981 10.251 1.000 41.461  0 27  LEU B CB    1 ? ? 
ATOM   2222 C CG    . LEU B 1 46  ? -3.003  66.497 10.167 1.000 43.731  0 27  LEU B CG    1 ? ? 
ATOM   2223 C CD1   . LEU B 1 46  ? -4.232  67.190 9.576  1.000 45.708  0 27  LEU B CD1   1 ? ? 
ATOM   2224 C CD2   . LEU B 1 46  ? -2.680  67.012 11.562 1.000 42.947  0 27  LEU B CD2   1 ? ? 
ATOM   2225 N N     . TYR B 1 47  ? -2.724  61.964 10.491 1.000 34.400  0 28  TYR B N     1 ? ? 
ATOM   2226 C CA    . TYR B 1 47  ? -3.038  60.758 11.215 1.000 31.990  0 28  TYR B CA    1 ? ? 
ATOM   2227 C C     . TYR B 1 47  ? -1.769  60.005 11.590 1.000 31.865  0 28  TYR B C     1 ? ? 
ATOM   2228 O O     . TYR B 1 47  ? -1.692  59.456 12.687 1.000 33.538  0 28  TYR B O     1 ? ? 
ATOM   2229 C CB    . TYR B 1 47  ? -3.978  59.878 10.395 1.000 32.581  0 28  TYR B CB    1 ? ? 
ATOM   2230 C CG    . TYR B 1 47  ? -4.181  58.505 10.992 1.000 33.237  0 28  TYR B CG    1 ? ? 
ATOM   2231 C CD1   . TYR B 1 47  ? -4.913  58.311 12.163 1.000 31.913  0 28  TYR B CD1   1 ? ? 
ATOM   2232 C CD2   . TYR B 1 47  ? -3.619  57.401 10.377 1.000 31.452  0 28  TYR B CD2   1 ? ? 
ATOM   2233 C CE1   . TYR B 1 47  ? -5.110  57.045 12.696 1.000 31.209  0 28  TYR B CE1   1 ? ? 
ATOM   2234 C CE2   . TYR B 1 47  ? -3.776  56.141 10.912 1.000 31.439  0 28  TYR B CE2   1 ? ? 
ATOM   2235 C CZ    . TYR B 1 47  ? -4.531  55.958 12.060 1.000 30.648  0 28  TYR B CZ    1 ? ? 
ATOM   2236 O OH    . TYR B 1 47  ? -4.675  54.689 12.545 1.000 27.983  0 28  TYR B OH    1 ? ? 
ATOM   2237 N N     . LYS B 1 48  ? -0.785  59.982 10.681 1.000 30.142  0 29  LYS B N     1 ? ? 
ATOM   2238 C CA    . LYS B 1 48  ? 0.276   58.996 10.786 1.000 28.076  0 29  LYS B CA    1 ? ? 
ATOM   2239 C C     . LYS B 1 48  ? 1.078   59.192 12.065 1.000 26.837  0 29  LYS B C     1 ? ? 
ATOM   2240 O O     . LYS B 1 48  ? 1.676   58.240 12.550 1.000 27.416  0 29  LYS B O     1 ? ? 
ATOM   2241 C CB    . LYS B 1 48  ? 1.177   58.968 9.551  1.000 28.106  0 29  LYS B CB    1 ? ? 
ATOM   2242 C CG    . LYS B 1 48  ? 2.116   60.141 9.396  1.000 27.308  0 29  LYS B CG    1 ? ? 
ATOM   2243 C CD    . LYS B 1 48  ? 2.931   59.990 8.163  1.000 29.644  0 29  LYS B CD    1 ? ? 
ATOM   2244 C CE    . LYS B 1 48  ? 3.422   61.332 7.685  1.000 31.569  0 29  LYS B CE    1 ? ? 
ATOM   2245 N NZ    . LYS B 1 48  ? 3.830   61.224 6.281  1.000 32.590  0 29  LYS B NZ    1 ? ? 
ATOM   2246 N N     . LYS B 1 49  ? 1.086   60.410 12.608 1.000 26.744  0 30  LYS B N     1 ? ? 
ATOM   2247 C CA    . LYS B 1 49  ? 1.936   60.652 13.759 1.000 27.414  0 30  LYS B CA    1 ? ? 
ATOM   2248 C C     . LYS B 1 49  ? 1.129   61.021 14.994 1.000 25.231  0 30  LYS B C     1 ? ? 
ATOM   2249 O O     . LYS B 1 49  ? 1.704   61.397 16.003 1.000 22.961  0 30  LYS B O     1 ? ? 
ATOM   2250 C CB    . LYS B 1 49  ? 2.981   61.737 13.485 1.000 28.248  0 30  LYS B CB    1 ? ? 
ATOM   2251 C CG    . LYS B 1 49  ? 3.975   61.385 12.397 1.000 30.338  0 30  LYS B CG    1 ? ? 
ATOM   2252 C CD    . LYS B 1 49  ? 4.958   62.467 12.142 1.000 30.418  0 30  LYS B CD    1 ? ? 
ATOM   2253 C CE    . LYS B 1 49  ? 5.980   62.064 11.114 1.000 30.676  0 30  LYS B CE    1 ? ? 
ATOM   2254 N NZ    . LYS B 1 49  ? 7.300   62.660 11.470 1.000 30.854  0 30  LYS B NZ    1 ? ? 
ATOM   2255 N N     . SER B 1 50  ? -0.195  60.917 14.911 1.000 25.687  0 31  SER B N     1 ? ? 
ATOM   2256 C CA    . SER B 1 50  ? -1.024  61.357 16.010 1.000 25.844  0 31  SER B CA    1 ? ? 
ATOM   2257 C C     . SER B 1 50  ? -0.796  60.463 17.212 1.000 26.547  0 31  SER B C     1 ? ? 
ATOM   2258 O O     . SER B 1 50  ? -1.104  59.269 17.125 1.000 26.584  0 31  SER B O     1 ? ? 
ATOM   2259 C CB    . SER B 1 50  ? -2.449  61.374 15.613 1.000 25.371  0 31  SER B CB    1 ? ? 
ATOM   2260 O OG    . SER B 1 50  ? -3.166  62.114 16.571 1.000 26.850  0 31  SER B OG    1 ? ? 
ATOM   2261 N N     . GLY B 1 51  ? -0.282  61.052 18.306 1.000 26.688  0 32  GLY B N     1 ? ? 
ATOM   2262 C CA    . GLY B 1 51  ? -0.138  60.364 19.579 1.000 25.477  0 32  GLY B CA    1 ? ? 
ATOM   2263 C C     . GLY B 1 51  ? 1.030   59.378 19.639 1.000 25.096  0 32  GLY B C     1 ? ? 
ATOM   2264 O O     . GLY B 1 51  ? 1.193   58.724 20.660 1.000 25.601  0 32  GLY B O     1 ? ? 
ATOM   2265 N N     . ILE B 1 52  ? 1.819   59.247 18.569 1.000 24.718  0 33  ILE B N     1 ? ? 
ATOM   2266 C CA    . ILE B 1 52  ? 2.968   58.348 18.543 1.000 25.010  0 33  ILE B CA    1 ? ? 
ATOM   2267 C C     . ILE B 1 52  ? 4.134   58.999 19.285 1.000 23.987  0 33  ILE B C     1 ? ? 
ATOM   2268 O O     . ILE B 1 52  ? 4.064   60.167 19.674 1.000 24.401  0 33  ILE B O     1 ? ? 
ATOM   2269 C CB    . ILE B 1 52  ? 3.381   57.975 17.092 1.000 24.759  0 33  ILE B CB    1 ? ? 
ATOM   2270 C CG1   . ILE B 1 52  ? 4.327   59.016 16.467 1.000 23.337  0 33  ILE B CG1   1 ? ? 
ATOM   2271 C CG2   . ILE B 1 52  ? 2.149   57.709 16.224 1.000 22.441  0 33  ILE B CG2   1 ? ? 
ATOM   2272 C CD1   . ILE B 1 52  ? 5.286   58.484 15.410 1.000 24.766  0 33  ILE B CD1   1 ? ? 
ATOM   2273 N N     . THR B 1 53  ? 5.205   58.222 19.448 1.000 23.787  0 34  THR B N     1 ? ? 
ATOM   2274 C CA    . THR B 1 53  ? 6.457   58.724 19.991 1.000 24.236  0 34  THR B CA    1 ? ? 
ATOM   2275 C C     . THR B 1 53  ? 7.442   58.808 18.835 1.000 24.580  0 34  THR B C     1 ? ? 
ATOM   2276 O O     . THR B 1 53  ? 7.371   58.004 17.916 1.000 27.492  0 34  THR B O     1 ? ? 
ATOM   2277 C CB    . THR B 1 53  ? 6.961   57.831 21.134 1.000 23.016  0 34  THR B CB    1 ? ? 
ATOM   2278 O OG1   . THR B 1 53  ? 5.969   57.731 22.156 1.000 23.287  0 34  THR B OG1   1 ? ? 
ATOM   2279 C CG2   . THR B 1 53  ? 8.211   58.376 21.779 1.000 21.092  0 34  THR B CG2   1 ? ? 
ATOM   2280 N N     . GLU B 1 54  ? 8.342   59.794 18.858 1.000 25.441  0 35  GLU B N     1 ? ? 
ATOM   2281 C CA    . GLU B 1 54  ? 9.314   59.920 17.787 1.000 25.378  0 35  GLU B CA    1 ? ? 
ATOM   2282 C C     . GLU B 1 54  ? 10.586  60.577 18.290 1.000 25.454  0 35  GLU B C     1 ? ? 
ATOM   2283 O O     . GLU B 1 54  ? 10.523  61.473 19.117 1.000 27.721  0 35  GLU B O     1 ? ? 
ATOM   2284 C CB    . GLU B 1 54  ? 8.652   60.556 16.565 1.000 28.322  0 35  GLU B CB    1 ? ? 
ATOM   2285 C CG    . GLU B 1 54  ? 9.039   61.967 16.252 1.000 29.375  0 35  GLU B CG    1 ? ? 
ATOM   2286 C CD    . GLU B 1 54  ? 8.731   62.510 14.868 1.000 31.724  0 35  GLU B CD    1 ? ? 
ATOM   2287 O OE1   . GLU B 1 54  ? 9.106   63.649 14.675 1.000 32.402  0 35  GLU B OE1   1 ? ? 
ATOM   2288 O OE2   . GLU B 1 54  ? 8.100   61.829 14.019 1.000 34.886  0 35  GLU B OE2   1 ? ? 
ATOM   2289 N N     . VAL B 1 55  ? 11.730  60.112 17.787 1.000 23.695  0 36  VAL B N     1 ? ? 
ATOM   2290 C CA    . VAL B 1 55  ? 12.977  60.727 18.184 1.000 23.416  0 36  VAL B CA    1 ? ? 
ATOM   2291 C C     . VAL B 1 55  ? 13.295  61.881 17.250 1.000 22.758  0 36  VAL B C     1 ? ? 
ATOM   2292 O O     . VAL B 1 55  ? 12.871  61.897 16.102 1.000 21.731  0 36  VAL B O     1 ? ? 
ATOM   2293 C CB    . VAL B 1 55  ? 14.122  59.712 18.318 1.000 24.611  0 36  VAL B CB    1 ? ? 
ATOM   2294 C CG1   . VAL B 1 55  ? 13.761  58.664 19.366 1.000 24.174  0 36  VAL B CG1   1 ? ? 
ATOM   2295 C CG2   . VAL B 1 55  ? 14.453  59.084 16.972 1.000 24.963  0 36  VAL B CG2   1 ? ? 
ATOM   2296 N N     . ASP B 1 56  ? 14.008  62.856 17.811 1.000 23.625  0 37  ASP B N     1 ? ? 
ATOM   2297 C CA    . ASP B 1 56  ? 14.438  64.030 17.087 1.000 23.770  0 37  ASP B CA    1 ? ? 
ATOM   2298 C C     . ASP B 1 56  ? 15.704  63.713 16.306 1.000 23.534  0 37  ASP B C     1 ? ? 
ATOM   2299 O O     . ASP B 1 56  ? 16.788  63.578 16.876 1.000 22.608  0 37  ASP B O     1 ? ? 
ATOM   2300 C CB    . ASP B 1 56  ? 14.667  65.212 18.021 1.000 25.252  0 37  ASP B CB    1 ? ? 
ATOM   2301 C CG    . ASP B 1 56  ? 14.769  66.514 17.256 1.000 27.172  0 37  ASP B CG    1 ? ? 
ATOM   2302 O OD1   . ASP B 1 56  ? 14.642  66.489 16.010 1.000 28.040  0 37  ASP B OD1   1 ? ? 
ATOM   2303 O OD2   . ASP B 1 56  ? 15.023  67.524 17.889 1.000 28.393  0 37  ASP B OD2   1 ? ? 
ATOM   2304 N N     . ARG B 1 57  ? 15.553  63.658 14.982 1.000 24.223  0 38  ARG B N     1 ? ? 
ATOM   2305 C CA    . ARG B 1 57  ? 16.645  63.209 14.147 1.000 26.218  0 38  ARG B CA    1 ? ? 
ATOM   2306 C C     . ARG B 1 57  ? 17.426  64.385 13.573 1.000 28.412  0 38  ARG B C     1 ? ? 
ATOM   2307 O O     . ARG B 1 57  ? 18.359  64.167 12.808 1.000 31.237  0 38  ARG B O     1 ? ? 
ATOM   2308 C CB    . ARG B 1 57  ? 16.108  62.309 13.030 1.000 23.887  0 38  ARG B CB    1 ? ? 
ATOM   2309 C CG    . ARG B 1 57  ? 15.594  60.972 13.540 1.000 23.039  0 38  ARG B CG    1 ? ? 
ATOM   2310 C CD    . ARG B 1 57  ? 16.719  59.978 13.744 1.000 22.372  0 38  ARG B CD    1 ? ? 
ATOM   2311 N NE    . ARG B 1 57  ? 17.456  59.769 12.513 1.000 21.653  0 38  ARG B NE    1 ? ? 
ATOM   2312 C CZ    . ARG B 1 57  ? 18.676  59.275 12.433 1.000 21.299  0 38  ARG B CZ    1 ? ? 
ATOM   2313 N NH1   . ARG B 1 57  ? 19.318  58.895 13.523 1.000 22.284  0 38  ARG B NH1   1 ? ? 
ATOM   2314 N NH2   . ARG B 1 57  ? 19.225  59.140 11.244 1.000 19.330  0 38  ARG B NH2   1 ? ? 
ATOM   2315 N N     . THR B 1 58  ? 17.071  65.618 13.944 1.000 31.998  0 39  THR B N     1 ? ? 
ATOM   2316 C CA    . THR B 1 58  ? 17.640  66.780 13.279 1.000 35.131  0 39  THR B CA    1 ? ? 
ATOM   2317 C C     . THR B 1 58  ? 19.163  66.762 13.369 1.000 36.936  0 39  THR B C     1 ? ? 
ATOM   2318 O O     . THR B 1 58  ? 19.845  66.711 12.337 1.000 37.053  0 39  THR B O     1 ? ? 
ATOM   2319 C CB    . THR B 1 58  ? 17.050  68.078 13.834 1.000 34.945  0 39  THR B CB    1 ? ? 
ATOM   2320 O OG1   . THR B 1 58  ? 15.638  67.983 13.662 1.000 33.222  0 39  THR B OG1   1 ? ? 
ATOM   2321 C CG2   . THR B 1 58  ? 17.591  69.295 13.119 1.000 36.985  0 39  THR B CG2   1 ? ? 
ATOM   2322 N N     . GLU B 1 59  ? 19.672  66.759 14.611 1.000 38.250  0 40  GLU B N     1 ? ? 
ATOM   2323 C CA    . GLU B 1 59  ? 21.106  66.781 14.866 1.000 37.915  0 40  GLU B CA    1 ? ? 
ATOM   2324 C C     . GLU B 1 59  ? 21.812  65.674 14.089 1.000 34.950  0 40  GLU B C     1 ? ? 
ATOM   2325 O O     . GLU B 1 59  ? 22.824  65.939 13.439 1.000 32.431  0 40  GLU B O     1 ? ? 
ATOM   2326 C CB    . GLU B 1 59  ? 21.360  66.679 16.369 1.000 42.193  0 40  GLU B CB    1 ? ? 
ATOM   2327 C CG    . GLU B 1 59  ? 22.827  66.627 16.770 1.000 49.481  0 40  GLU B CG    1 ? ? 
ATOM   2328 C CD    . GLU B 1 59  ? 23.074  66.547 18.275 1.000 55.504  0 40  GLU B CD    1 ? ? 
ATOM   2329 O OE1   . GLU B 1 59  ? 22.149  66.904 19.050 1.000 56.823  0 40  GLU B OE1   1 ? ? 
ATOM   2330 O OE2   . GLU B 1 59  ? 24.187  66.121 18.683 1.000 53.195  0 40  GLU B OE2   1 ? ? 
ATOM   2331 N N     . ALA B 1 60  ? 21.257  64.457 14.162 1.000 32.237  0 41  ALA B N     1 ? ? 
ATOM   2332 C CA    . ALA B 1 60  ? 21.839  63.291 13.522 1.000 31.600  0 41  ALA B CA    1 ? ? 
ATOM   2333 C C     . ALA B 1 60  ? 21.806  63.434 12.006 1.000 33.440  0 41  ALA B C     1 ? ? 
ATOM   2334 O O     . ALA B 1 60  ? 22.733  63.015 11.330 1.000 32.177  0 41  ALA B O     1 ? ? 
ATOM   2335 C CB    . ALA B 1 60  ? 21.128  62.043 13.965 1.000 29.170  0 41  ALA B CB    1 ? ? 
ATOM   2336 N N     . LYS B 1 61  ? 20.731  63.998 11.465 1.000 37.117  0 42  LYS B N     1 ? ? 
ATOM   2337 C CA    . LYS B 1 61  ? 20.634  64.128 10.019 1.000 38.316  0 42  LYS B CA    1 ? ? 
ATOM   2338 C C     . LYS B 1 61  ? 21.695  65.091 9.510  1.000 38.623  0 42  LYS B C     1 ? ? 
ATOM   2339 O O     . LYS B 1 61  ? 22.204  64.918 8.408  1.000 41.233  0 42  LYS B O     1 ? ? 
ATOM   2340 C CB    . LYS B 1 61  ? 19.266  64.692 9.629  1.000 37.753  0 42  LYS B CB    1 ? ? 
ATOM   2341 C CG    . LYS B 1 61  ? 18.151  63.676 9.439  1.000 38.169  0 42  LYS B CG    1 ? ? 
ATOM   2342 C CD    . LYS B 1 61  ? 16.818  64.381 9.521  1.000 40.681  0 42  LYS B CD    1 ? ? 
ATOM   2343 C CE    . LYS B 1 61  ? 15.637  63.527 9.120  1.000 42.704  0 42  LYS B CE    1 ? ? 
ATOM   2344 N NZ    . LYS B 1 61  ? 14.367  64.278 9.276  1.000 42.901  0 42  LYS B NZ    1 ? ? 
ATOM   2345 N N     . GLU B 1 62  ? 22.029  66.088 10.327 1.000 37.372  0 43  GLU B N     1 ? ? 
ATOM   2346 C CA    . GLU B 1 62  ? 22.978  67.090 9.884  1.000 38.982  0 43  GLU B CA    1 ? ? 
ATOM   2347 C C     . GLU B 1 62  ? 24.399  66.561 9.985  1.000 39.896  0 43  GLU B C     1 ? ? 
ATOM   2348 O O     . GLU B 1 62  ? 25.177  66.630 9.037  1.000 43.101  0 43  GLU B O     1 ? ? 
ATOM   2349 C CB    . GLU B 1 62  ? 22.722  68.384 10.638 1.000 41.102  0 43  GLU B CB    1 ? ? 
ATOM   2350 C CG    . GLU B 1 62  ? 21.461  69.043 10.118 1.000 44.608  0 43  GLU B CG    1 ? ? 
ATOM   2351 C CD    . GLU B 1 62  ? 21.276  69.066 8.595  1.000 46.621  0 43  GLU B CD    1 ? ? 
ATOM   2352 O OE1   . GLU B 1 62  ? 20.755  68.059 8.035  1.000 44.483  0 43  GLU B OE1   1 ? ? 
ATOM   2353 O OE2   . GLU B 1 62  ? 21.626  70.097 7.958  1.000 47.534  0 43  GLU B OE2   1 ? ? 
ATOM   2354 N N     . GLY B 1 63  ? 24.702  65.934 11.112 1.000 37.337  0 44  GLY B N     1 ? ? 
ATOM   2355 C CA    . GLY B 1 63  ? 26.008  65.325 11.268 1.000 32.597  0 44  GLY B CA    1 ? ? 
ATOM   2356 C C     . GLY B 1 63  ? 26.313  64.294 10.191 1.000 29.514  0 44  GLY B C     1 ? ? 
ATOM   2357 O O     . GLY B 1 63  ? 27.433  64.227 9.706  1.000 29.823  0 44  GLY B O     1 ? ? 
ATOM   2358 N N     . LEU B 1 64  ? 25.317  63.492 9.824  1.000 29.882  0 45  LEU B N     1 ? ? 
ATOM   2359 C CA    . LEU B 1 64  ? 25.525  62.462 8.820  1.000 31.216  0 45  LEU B CA    1 ? ? 
ATOM   2360 C C     . LEU B 1 64  ? 25.736  63.090 7.447  1.000 32.101  0 45  LEU B C     1 ? ? 
ATOM   2361 O O     . LEU B 1 64  ? 26.412  62.511 6.600  1.000 31.608  0 45  LEU B O     1 ? ? 
ATOM   2362 C CB    . LEU B 1 64  ? 24.327  61.511 8.775  1.000 31.073  0 45  LEU B CB    1 ? ? 
ATOM   2363 C CG    . LEU B 1 64  ? 24.219  60.533 9.938  1.000 32.809  0 45  LEU B CG    1 ? ? 
ATOM   2364 C CD1   . LEU B 1 64  ? 22.824  59.907 9.964  1.000 31.563  0 45  LEU B CD1   1 ? ? 
ATOM   2365 C CD2   . LEU B 1 64  ? 25.305  59.467 9.863  1.000 30.135  0 45  LEU B CD2   1 ? ? 
ATOM   2366 N N     . LYS B 1 65  ? 25.108  64.244 7.215  1.000 32.642  0 46  LYS B N     1 ? ? 
ATOM   2367 C CA    . LYS B 1 65  ? 25.284  64.972 5.974  1.000 34.416  0 46  LYS B CA    1 ? ? 
ATOM   2368 C C     . LYS B 1 65  ? 26.721  65.478 5.867  1.000 34.205  0 46  LYS B C     1 ? ? 
ATOM   2369 O O     . LYS B 1 65  ? 27.290  65.530 4.776  1.000 36.150  0 46  LYS B O     1 ? ? 
ATOM   2370 C CB    . LYS B 1 65  ? 24.287  66.126 5.979  1.000 37.311  0 46  LYS B CB    1 ? ? 
ATOM   2371 C CG    . LYS B 1 65  ? 24.078  66.834 4.668  1.000 40.202  0 46  LYS B CG    1 ? ? 
ATOM   2372 C CD    . LYS B 1 65  ? 23.168  68.006 4.887  1.000 43.287  0 46  LYS B CD    1 ? ? 
ATOM   2373 C CE    . LYS B 1 65  ? 23.962  69.280 5.075  1.000 46.142  0 46  LYS B CE    1 ? ? 
ATOM   2374 N NZ    . LYS B 1 65  ? 23.109  70.465 4.849  1.000 46.616  0 46  LYS B NZ    1 ? ? 
ATOM   2375 N N     . ARG B 1 66  ? 27.309  65.845 7.012  1.000 32.500  0 47  ARG B N     1 ? ? 
ATOM   2376 C CA    . ARG B 1 66  ? 28.687  66.303 7.064  1.000 33.664  0 47  ARG B CA    1 ? ? 
ATOM   2377 C C     . ARG B 1 66  ? 29.672  65.138 7.107  1.000 32.547  0 47  ARG B C     1 ? ? 
ATOM   2378 O O     . ARG B 1 66  ? 30.866  65.380 7.229  1.000 34.497  0 47  ARG B O     1 ? ? 
ATOM   2379 C CB    . ARG B 1 66  ? 28.883  67.205 8.280  1.000 34.930  0 47  ARG B CB    1 ? ? 
ATOM   2380 C CG    . ARG B 1 66  ? 28.168  68.539 8.137  1.000 38.172  0 47  ARG B CG    1 ? ? 
ATOM   2381 C CD    . ARG B 1 66  ? 28.091  69.355 9.408  1.000 41.489  0 47  ARG B CD    1 ? ? 
ATOM   2382 N NE    . ARG B 1 66  ? 29.424  69.818 9.714  1.000 48.266  0 47  ARG B NE    1 ? ? 
ATOM   2383 C CZ    . ARG B 1 66  ? 30.023  70.898 9.184  1.000 52.153  0 47  ARG B CZ    1 ? ? 
ATOM   2384 N NH1   . ARG B 1 66  ? 31.263  71.198 9.541  1.000 51.806  0 47  ARG B NH1   1 ? ? 
ATOM   2385 N NH2   . ARG B 1 66  ? 29.405  71.651 8.284  1.000 46.363  0 47  ARG B NH2   1 ? ? 
ATOM   2386 N N     . GLY B 1 67  ? 29.172  63.900 7.007  1.000 31.301  0 48  GLY B N     1 ? ? 
ATOM   2387 C CA    . GLY B 1 67  ? 30.014  62.719 6.921  1.000 29.342  0 48  GLY B CA    1 ? ? 
ATOM   2388 C C     . GLY B 1 67  ? 30.589  62.278 8.268  1.000 29.097  0 48  GLY B C     1 ? ? 
ATOM   2389 O O     . GLY B 1 67  ? 31.516  61.464 8.288  1.000 27.780  0 48  GLY B O     1 ? ? 
ATOM   2390 N N     . GLU B 1 68  ? 30.017  62.776 9.378  1.000 26.707  0 49  GLU B N     1 ? ? 
ATOM   2391 C CA    . GLU B 1 68  ? 30.437  62.356 10.706 1.000 25.503  0 49  GLU B CA    1 ? ? 
ATOM   2392 C C     . GLU B 1 68  ? 30.044  60.901 10.959 1.000 25.934  0 49  GLU B C     1 ? ? 
ATOM   2393 O O     . GLU B 1 68  ? 28.994  60.431 10.518 1.000 24.102  0 49  GLU B O     1 ? ? 
ATOM   2394 C CB    . GLU B 1 68  ? 29.829  63.251 11.779 1.000 26.512  0 49  GLU B CB    1 ? ? 
ATOM   2395 C CG    . GLU B 1 68  ? 30.344  64.669 11.757 1.000 27.382  0 49  GLU B CG    1 ? ? 
ATOM   2396 C CD    . GLU B 1 68  ? 29.478  65.690 12.476 1.000 28.774  0 49  GLU B CD    1 ? ? 
ATOM   2397 O OE1   . GLU B 1 68  ? 29.590  66.855 12.113 1.000 28.774  0 49  GLU B OE1   1 ? ? 
ATOM   2398 O OE2   . GLU B 1 68  ? 28.676  65.327 13.352 1.000 29.730  0 49  GLU B OE2   1 ? ? 
ATOM   2399 N N     . THR B 1 69  ? 30.939  60.196 11.662 1.000 27.177  0 50  THR B N     1 ? ? 
ATOM   2400 C CA    . THR B 1 69  ? 30.859  58.753 11.798 1.000 26.117  0 50  THR B CA    1 ? ? 
ATOM   2401 C C     . THR B 1 69  ? 30.730  58.339 13.260 1.000 26.296  0 50  THR B C     1 ? ? 
ATOM   2402 O O     . THR B 1 69  ? 30.795  57.144 13.543 1.000 27.099  0 50  THR B O     1 ? ? 
ATOM   2403 C CB    . THR B 1 69  ? 32.112  58.078 11.226 1.000 26.208  0 50  THR B CB    1 ? ? 
ATOM   2404 O OG1   . THR B 1 69  ? 33.259  58.772 11.704 1.000 26.730  0 50  THR B OG1   1 ? ? 
ATOM   2405 C CG2   . THR B 1 69  ? 32.151  58.073 9.717  1.000 24.337  0 50  THR B CG2   1 ? ? 
ATOM   2406 N N     . THR B 1 70  ? 30.588  59.309 14.174 1.000 25.326  0 51  THR B N     1 ? ? 
ATOM   2407 C CA    . THR B 1 70  ? 30.523  58.998 15.594 1.000 23.994  0 51  THR B CA    1 ? ? 
ATOM   2408 C C     . THR B 1 70  ? 29.226  59.547 16.165 1.000 24.640  0 51  THR B C     1 ? ? 
ATOM   2409 O O     . THR B 1 70  ? 28.730  60.564 15.688 1.000 23.267  0 51  THR B O     1 ? ? 
ATOM   2410 C CB    . THR B 1 70  ? 31.731  59.557 16.355 1.000 24.779  0 51  THR B CB    1 ? ? 
ATOM   2411 O OG1   . THR B 1 70  ? 31.744  60.971 16.158 1.000 26.714  0 51  THR B OG1   1 ? ? 
ATOM   2412 C CG2   . THR B 1 70  ? 33.033  58.921 15.920 1.000 23.050  0 51  THR B CG2   1 ? ? 
ATOM   2413 N N     . HIS B 1 71  ? 28.707  58.846 17.186 1.000 24.155  0 52  HIS B N     1 ? ? 
ATOM   2414 C CA    . HIS B 1 71  ? 27.570  59.262 17.994 1.000 24.080  0 52  HIS B CA    1 ? ? 
ATOM   2415 C C     . HIS B 1 71  ? 26.220  59.012 17.313 1.000 24.489  0 52  HIS B C     1 ? ? 
ATOM   2416 O O     . HIS B 1 71  ? 25.318  58.463 17.952 1.000 24.025  0 52  HIS B O     1 ? ? 
ATOM   2417 C CB    . HIS B 1 71  ? 27.693  60.715 18.459 1.000 24.005  0 52  HIS B CB    1 ? ? 
ATOM   2418 C CG    . HIS B 1 71  ? 28.892  60.963 19.308 1.000 25.551  0 52  HIS B CG    1 ? ? 
ATOM   2419 N ND1   . HIS B 1 71  ? 28.934  60.535 20.625 1.000 25.197  0 52  HIS B ND1   1 ? ? 
ATOM   2420 C CD2   . HIS B 1 71  ? 30.054  61.624 19.077 1.000 24.673  0 52  HIS B CD2   1 ? ? 
ATOM   2421 C CE1   . HIS B 1 71  ? 30.085  60.877 21.154 1.000 24.312  0 52  HIS B CE1   1 ? ? 
ATOM   2422 N NE2   . HIS B 1 71  ? 30.797  61.540 20.220 1.000 24.251  0 52  HIS B NE2   1 ? ? 
ATOM   2423 N N     . HIS B 1 72  ? 26.082  59.391 16.032 1.000 23.304  0 53  HIS B N     1 ? ? 
ATOM   2424 C CA    . HIS B 1 72  ? 24.798  59.399 15.345 1.000 21.981  0 53  HIS B CA    1 ? ? 
ATOM   2425 C C     . HIS B 1 72  ? 24.330  57.982 15.020 1.000 22.037  0 53  HIS B C     1 ? ? 
ATOM   2426 O O     . HIS B 1 72  ? 25.137  57.143 14.619 1.000 23.384  0 53  HIS B O     1 ? ? 
ATOM   2427 C CB    . HIS B 1 72  ? 24.909  60.197 14.035 1.000 22.267  0 53  HIS B CB    1 ? ? 
ATOM   2428 C CG    . HIS B 1 72  ? 25.579  61.530 14.156 1.000 22.319  0 53  HIS B CG    1 ? ? 
ATOM   2429 N ND1   . HIS B 1 72  ? 25.182  62.487 15.075 1.000 21.865  0 53  HIS B ND1   1 ? ? 
ATOM   2430 C CD2   . HIS B 1 72  ? 26.588  62.090 13.450 1.000 22.446  0 53  HIS B CD2   1 ? ? 
ATOM   2431 C CE1   . HIS B 1 72  ? 25.929  63.559 14.946 1.000 21.712  0 53  HIS B CE1   1 ? ? 
ATOM   2432 N NE2   . HIS B 1 72  ? 26.801  63.344 13.962 1.000 21.544  0 53  HIS B NE2   1 ? ? 
ATOM   2433 N N     . ALA B 1 73  ? 23.023  57.731 15.198 1.000 21.435  0 54  ALA B N     1 ? ? 
ATOM   2434 C CA    . ALA B 1 73  ? 22.373  56.558 14.614 1.000 21.745  0 54  ALA B CA    1 ? ? 
ATOM   2435 C C     . ALA B 1 73  ? 22.143  56.771 13.114 1.000 20.620  0 54  ALA B C     1 ? ? 
ATOM   2436 O O     . ALA B 1 73  ? 21.784  57.865 12.705 1.000 19.754  0 54  ALA B O     1 ? ? 
ATOM   2437 C CB    . ALA B 1 73  ? 21.054  56.295 15.304 1.000 20.497  0 54  ALA B CB    1 ? ? 
ATOM   2438 N N     . VAL B 1 74  ? 22.298  55.725 12.298 1.000 20.805  0 55  VAL B N     1 ? ? 
ATOM   2439 C CA    . VAL B 1 74  ? 22.168  55.890 10.854 1.000 22.701  0 55  VAL B CA    1 ? ? 
ATOM   2440 C C     . VAL B 1 74  ? 20.706  56.041 10.446 1.000 24.144  0 55  VAL B C     1 ? ? 
ATOM   2441 O O     . VAL B 1 74  ? 20.429  56.579 9.390  1.000 24.501  0 55  VAL B O     1 ? ? 
ATOM   2442 C CB    . VAL B 1 74  ? 22.869  54.771 10.064 1.000 21.204  0 55  VAL B CB    1 ? ? 
ATOM   2443 C CG1   . VAL B 1 74  ? 24.351  54.730 10.404 1.000 20.960  0 55  VAL B CG1   1 ? ? 
ATOM   2444 C CG2   . VAL B 1 74  ? 22.232  53.416 10.301 1.000 20.343  0 55  VAL B CG2   1 ? ? 
ATOM   2445 N N     . SER B 1 75  ? 19.779  55.592 11.289 1.000 26.127  0 56  SER B N     1 ? ? 
ATOM   2446 C CA    . SER B 1 75  ? 18.355  55.642 10.986 1.000 25.374  0 56  SER B CA    1 ? ? 
ATOM   2447 C C     . SER B 1 75  ? 17.583  55.758 12.301 1.000 25.263  0 56  SER B C     1 ? ? 
ATOM   2448 O O     . SER B 1 75  ? 18.179  55.702 13.382 1.000 26.757  0 56  SER B O     1 ? ? 
ATOM   2449 C CB    . SER B 1 75  ? 17.915  54.412 10.233 1.000 23.594  0 56  SER B CB    1 ? ? 
ATOM   2450 O OG    . SER B 1 75  ? 17.928  53.287 11.102 1.000 24.991  0 56  SER B OG    1 ? ? 
ATOM   2451 N N     . ARG B 1 76  ? 16.254  55.874 12.174 1.000 22.981  0 57  ARG B N     1 ? ? 
ATOM   2452 C CA    . ARG B 1 76  ? 15.324  55.853 13.289 1.000 20.951  0 57  ARG B CA    1 ? ? 
ATOM   2453 C C     . ARG B 1 76  ? 15.284  54.461 13.919 1.000 20.820  0 57  ARG B C     1 ? ? 
ATOM   2454 O O     . ARG B 1 76  ? 14.672  54.270 14.981 1.000 20.321  0 57  ARG B O     1 ? ? 
ATOM   2455 C CB    . ARG B 1 76  ? 13.920  56.247 12.821 1.000 19.635  0 57  ARG B CB    1 ? ? 
ATOM   2456 C CG    . ARG B 1 76  ? 13.779  57.728 12.509 1.000 18.928  0 57  ARG B CG    1 ? ? 
ATOM   2457 C CD    . ARG B 1 76  ? 12.330  58.143 12.369 1.000 19.017  0 57  ARG B CD    1 ? ? 
ATOM   2458 N NE    . ARG B 1 76  ? 12.236  59.553 12.014 1.000 19.816  0 57  ARG B NE    1 ? ? 
ATOM   2459 C CZ    . ARG B 1 76  ? 12.192  60.532 12.898 1.000 19.585  0 57  ARG B CZ    1 ? ? 
ATOM   2460 N NH1   . ARG B 1 76  ? 12.068  61.776 12.489 1.000 18.674  0 57  ARG B NH1   1 ? ? 
ATOM   2461 N NH2   . ARG B 1 76  ? 12.189  60.265 14.190 1.000 18.452  0 57  ARG B NH2   1 ? ? 
ATOM   2462 N N     . GLY B 1 77  ? 15.945  53.496 13.262 1.000 19.794  0 58  GLY B N     1 ? ? 
ATOM   2463 C CA    . GLY B 1 77  ? 15.894  52.104 13.676 1.000 18.459  0 58  GLY B CA    1 ? ? 
ATOM   2464 C C     . GLY B 1 77  ? 16.632  51.838 14.987 1.000 17.203  0 58  GLY B C     1 ? ? 
ATOM   2465 O O     . GLY B 1 77  ? 16.212  50.993 15.775 1.000 16.625  0 58  GLY B O     1 ? ? 
ATOM   2466 N N     . SER B 1 78  ? 17.729  52.562 15.220 1.000 15.984  0 59  SER B N     1 ? ? 
ATOM   2467 C CA    . SER B 1 78  ? 18.490  52.319 16.429 1.000 16.101  0 59  SER B CA    1 ? ? 
ATOM   2468 C C     . SER B 1 78  ? 17.586  52.543 17.641 1.000 16.024  0 59  SER B C     1 ? ? 
ATOM   2469 O O     . SER B 1 78  ? 17.435  51.657 18.472 1.000 16.348  0 59  SER B O     1 ? ? 
ATOM   2470 C CB    . SER B 1 78  ? 19.718  53.172 16.476 1.000 16.373  0 59  SER B CB    1 ? ? 
ATOM   2471 O OG    . SER B 1 78  ? 20.561  52.881 15.377 1.000 16.650  0 59  SER B OG    1 ? ? 
ATOM   2472 N N     . ALA B 1 79  ? 16.922  53.704 17.676 1.000 15.589  0 60  ALA B N     1 ? ? 
ATOM   2473 C CA    . ALA B 1 79  ? 16.014  54.049 18.751 1.000 15.386  0 60  ALA B CA    1 ? ? 
ATOM   2474 C C     . ALA B 1 79  ? 14.884  53.031 18.839 1.000 16.404  0 60  ALA B C     1 ? ? 
ATOM   2475 O O     . ALA B 1 79  ? 14.447  52.691 19.940 1.000 18.106  0 60  ALA B O     1 ? ? 
ATOM   2476 C CB    . ALA B 1 79  ? 15.493  55.453 18.593 1.000 14.213  0 60  ALA B CB    1 ? ? 
ATOM   2477 N N     . LYS B 1 80  ? 14.393  52.563 17.691 1.000 17.277  0 61  LYS B N     1 ? ? 
ATOM   2478 C CA    . LYS B 1 80  ? 13.256  51.657 17.666 1.000 17.847  0 61  LYS B CA    1 ? ? 
ATOM   2479 C C     . LYS B 1 80  ? 13.614  50.338 18.347 1.000 18.111  0 61  LYS B C     1 ? ? 
ATOM   2480 O O     . LYS B 1 80  ? 12.837  49.824 19.165 1.000 18.163  0 61  LYS B O     1 ? ? 
ATOM   2481 C CB    . LYS B 1 80  ? 12.740  51.479 16.234 1.000 17.738  0 61  LYS B CB    1 ? ? 
ATOM   2482 C CG    . LYS B 1 80  ? 11.404  50.757 16.121 1.000 17.849  0 61  LYS B CG    1 ? ? 
ATOM   2483 C CD    . LYS B 1 80  ? 11.088  50.348 14.707 1.000 17.872  0 61  LYS B CD    1 ? ? 
ATOM   2484 C CE    . LYS B 1 80  ? 9.643   50.589 14.314 1.000 18.681  0 61  LYS B CE    1 ? ? 
ATOM   2485 N NZ    . LYS B 1 80  ? 9.523   50.488 12.842 1.000 18.020  0 61  LYS B NZ    1 ? ? 
ATOM   2486 N N     . LEU B 1 81  ? 14.781  49.794 17.981 1.000 17.326  0 62  LEU B N     1 ? ? 
ATOM   2487 C CA    . LEU B 1 81  ? 15.207  48.548 18.591 1.000 17.684  0 62  LEU B CA    1 ? ? 
ATOM   2488 C C     . LEU B 1 81  ? 15.476  48.767 20.078 1.000 17.470  0 62  LEU B C     1 ? ? 
ATOM   2489 O O     . LEU B 1 81  ? 15.232  47.872 20.885 1.000 17.901  0 62  LEU B O     1 ? ? 
ATOM   2490 C CB    . LEU B 1 81  ? 16.433  47.980 17.868 1.000 16.741  0 62  LEU B CB    1 ? ? 
ATOM   2491 C CG    . LEU B 1 81  ? 16.940  46.627 18.369 1.000 16.684  0 62  LEU B CG    1 ? ? 
ATOM   2492 C CD1   . LEU B 1 81  ? 15.851  45.561 18.322 1.000 16.941  0 62  LEU B CD1   1 ? ? 
ATOM   2493 C CD2   . LEU B 1 81  ? 18.133  46.176 17.540 1.000 16.729  0 62  LEU B CD2   1 ? ? 
ATOM   2494 N N     . GLN B 1 82  ? 15.991  49.946 20.426 1.000 16.784  0 63  GLN B N     1 ? ? 
ATOM   2495 C CA    . GLN B 1 82  ? 16.329  50.248 21.802 1.000 17.133  0 63  GLN B CA    1 ? ? 
ATOM   2496 C C     . GLN B 1 82  ? 15.110  50.040 22.695 1.000 17.949  0 63  GLN B C     1 ? ? 
ATOM   2497 O O     . GLN B 1 82  ? 15.192  49.408 23.747 1.000 17.993  0 63  GLN B O     1 ? ? 
ATOM   2498 C CB    . GLN B 1 82  ? 16.862  51.671 21.938 1.000 16.811  0 63  GLN B CB    1 ? ? 
ATOM   2499 C CG    . GLN B 1 82  ? 17.240  51.950 23.378 1.000 16.887  0 63  GLN B CG    1 ? ? 
ATOM   2500 C CD    . GLN B 1 82  ? 17.870  53.301 23.607 1.000 16.667  0 63  GLN B CD    1 ? ? 
ATOM   2501 O OE1   . GLN B 1 82  ? 17.219  54.341 23.539 1.000 17.040  0 63  GLN B OE1   1 ? ? 
ATOM   2502 N NE2   . GLN B 1 82  ? 19.149  53.275 23.934 1.000 15.965  0 63  GLN B NE2   1 ? ? 
ATOM   2503 N N     . TRP B 1 83  ? 13.965  50.516 22.209 1.000 18.219  0 64  TRP B N     1 ? ? 
ATOM   2504 C CA    . TRP B 1 83  ? 12.731  50.428 22.960 1.000 18.804  0 64  TRP B CA    1 ? ? 
ATOM   2505 C C     . TRP B 1 83  ? 12.444  48.989 23.385 1.000 20.027  0 64  TRP B C     1 ? ? 
ATOM   2506 O O     . TRP B 1 83  ? 11.957  48.768 24.499 1.000 23.197  0 64  TRP B O     1 ? ? 
ATOM   2507 C CB    . TRP B 1 83  ? 11.575  51.024 22.156 1.000 18.247  0 64  TRP B CB    1 ? ? 
ATOM   2508 C CG    . TRP B 1 83  ? 10.339  51.163 22.982 1.000 17.874  0 64  TRP B CG    1 ? ? 
ATOM   2509 C CD1   . TRP B 1 83  ? 9.983   52.238 23.740 1.000 17.287  0 64  TRP B CD1   1 ? ? 
ATOM   2510 C CD2   . TRP B 1 83  ? 9.315   50.172 23.167 1.000 17.618  0 64  TRP B CD2   1 ? ? 
ATOM   2511 N NE1   . TRP B 1 83  ? 8.802   51.990 24.375 1.000 16.965  0 64  TRP B NE1   1 ? ? 
ATOM   2512 C CE2   . TRP B 1 83  ? 8.362   50.741 24.039 1.000 17.294  0 64  TRP B CE2   1 ? ? 
ATOM   2513 C CE3   . TRP B 1 83  ? 9.093   48.886 22.658 1.000 17.526  0 64  TRP B CE3   1 ? ? 
ATOM   2514 C CZ2   . TRP B 1 83  ? 7.201   50.067 24.416 1.000 17.191  0 64  TRP B CZ2   1 ? ? 
ATOM   2515 C CZ3   . TRP B 1 83  ? 7.930   48.228 23.007 1.000 16.867  0 64  TRP B CZ3   1 ? ? 
ATOM   2516 C CH2   . TRP B 1 83  ? 7.012   48.804 23.888 1.000 16.993  0 64  TRP B CH2   1 ? ? 
ATOM   2517 N N     . PHE B 1 84  ? 12.692  48.026 22.491 1.000 19.729  0 65  PHE B N     1 ? ? 
ATOM   2518 C CA    . PHE B 1 84  ? 12.458  46.628 22.823 1.000 19.734  0 65  PHE B CA    1 ? ? 
ATOM   2519 C C     . PHE B 1 84  ? 13.524  46.164 23.811 1.000 19.437  0 65  PHE B C     1 ? ? 
ATOM   2520 O O     . PHE B 1 84  ? 13.217  45.531 24.820 1.000 18.658  0 65  PHE B O     1 ? ? 
ATOM   2521 C CB    . PHE B 1 84  ? 12.494  45.704 21.602 1.000 19.477  0 65  PHE B CB    1 ? ? 
ATOM   2522 C CG    . PHE B 1 84  ? 11.393  45.888 20.593 1.000 21.599  0 65  PHE B CG    1 ? ? 
ATOM   2523 C CD1   . PHE B 1 84  ? 10.049  45.748 20.937 1.000 22.283  0 65  PHE B CD1   1 ? ? 
ATOM   2524 C CD2   . PHE B 1 84  ? 11.718  46.168 19.269 1.000 21.036  0 65  PHE B CD2   1 ? ? 
ATOM   2525 C CE1   . PHE B 1 84  ? 9.059   45.941 19.987 1.000 23.076  0 65  PHE B CE1   1 ? ? 
ATOM   2526 C CE2   . PHE B 1 84  ? 10.724  46.306 18.311 1.000 20.578  0 65  PHE B CE2   1 ? ? 
ATOM   2527 C CZ    . PHE B 1 84  ? 9.398   46.220 18.674 1.000 21.757  0 65  PHE B CZ    1 ? ? 
ATOM   2528 N N     . VAL B 1 85  ? 14.781  46.508 23.527 1.000 18.715  0 66  VAL B N     1 ? ? 
ATOM   2529 C CA    . VAL B 1 85  ? 15.890  45.956 24.284 1.000 18.480  0 66  VAL B CA    1 ? ? 
ATOM   2530 C C     . VAL B 1 85  ? 15.830  46.443 25.733 1.000 19.574  0 66  VAL B C     1 ? ? 
ATOM   2531 O O     . VAL B 1 85  ? 16.123  45.683 26.648 1.000 20.755  0 66  VAL B O     1 ? ? 
ATOM   2532 C CB    . VAL B 1 85  ? 17.236  46.280 23.608 1.000 17.448  0 66  VAL B CB    1 ? ? 
ATOM   2533 C CG1   . VAL B 1 85  ? 18.418  45.978 24.523 1.000 16.483  0 66  VAL B CG1   1 ? ? 
ATOM   2534 C CG2   . VAL B 1 85  ? 17.378  45.562 22.272 1.000 16.026  0 66  VAL B CG2   1 ? ? 
ATOM   2535 N N     . GLU B 1 86  ? 15.487  47.714 25.938 1.000 19.874  0 67  GLU B N     1 ? ? 
ATOM   2536 C CA    . GLU B 1 86  ? 15.460  48.245 27.286 1.000 19.685  0 67  GLU B CA    1 ? ? 
ATOM   2537 C C     . GLU B 1 86  ? 14.260  47.700 28.071 1.000 20.409  0 67  GLU B C     1 ? ? 
ATOM   2538 O O     . GLU B 1 86  ? 14.137  47.948 29.271 1.000 21.995  0 67  GLU B O     1 ? ? 
ATOM   2539 C CB    . GLU B 1 86  ? 15.552  49.771 27.228 1.000 19.158  0 67  GLU B CB    1 ? ? 
ATOM   2540 C CG    . GLU B 1 86  ? 14.309  50.467 26.716 1.000 20.457  0 67  GLU B CG    1 ? ? 
ATOM   2541 C CD    . GLU B 1 86  ? 14.529  51.954 26.489 1.000 21.836  0 67  GLU B CD    1 ? ? 
ATOM   2542 O OE1   . GLU B 1 86  ? 13.624  52.686 26.079 1.000 21.376  0 67  GLU B OE1   1 ? ? 
ATOM   2543 O OE2   . GLU B 1 86  ? 15.648  52.391 26.716 1.000 24.458  0 67  GLU B OE2   1 ? ? 
ATOM   2544 N N     . ARG B 1 87  ? 13.376  46.952 27.414 1.000 19.290  0 68  ARG B N     1 ? ? 
ATOM   2545 C CA    . ARG B 1 87  ? 12.263  46.328 28.114 1.000 19.125  0 68  ARG B CA    1 ? ? 
ATOM   2546 C C     . ARG B 1 87  ? 12.427  44.812 28.138 1.000 20.357  0 68  ARG B C     1 ? ? 
ATOM   2547 O O     . ARG B 1 87  ? 11.465  44.090 28.393 1.000 21.282  0 68  ARG B O     1 ? ? 
ATOM   2548 C CB    . ARG B 1 87  ? 10.934  46.696 27.451 1.000 17.863  0 68  ARG B CB    1 ? ? 
ATOM   2549 C CG    . ARG B 1 87  ? 10.366  48.031 27.911 1.000 16.757  0 68  ARG B CG    1 ? ? 
ATOM   2550 C CD    . ARG B 1 87  ? 9.532   48.726 26.856 1.000 16.155  0 68  ARG B CD    1 ? ? 
ATOM   2551 N NE    . ARG B 1 87  ? 9.254   50.080 27.300 1.000 16.141  0 68  ARG B NE    1 ? ? 
ATOM   2552 C CZ    . ARG B 1 87  ? 10.048  51.108 27.085 1.000 16.059  0 68  ARG B CZ    1 ? ? 
ATOM   2553 N NH1   . ARG B 1 87  ? 11.149  50.953 26.378 1.000 15.833  0 68  ARG B NH1   1 ? ? 
ATOM   2554 N NH2   . ARG B 1 87  ? 9.709   52.302 27.530 1.000 16.675  0 68  ARG B NH2   1 ? ? 
ATOM   2555 N N     . ASN B 1 88  ? 13.631  44.326 27.808 1.000 21.357  0 69  ASN B N     1 ? ? 
ATOM   2556 C CA    . ASN B 1 88  ? 13.964  42.906 27.868 1.000 21.589  0 69  ASN B CA    1 ? ? 
ATOM   2557 C C     . ASN B 1 88  ? 13.157  42.067 26.882 1.000 21.098  0 69  ASN B C     1 ? ? 
ATOM   2558 O O     . ASN B 1 88  ? 13.136  40.853 26.995 1.000 21.519  0 69  ASN B O     1 ? ? 
ATOM   2559 C CB    . ASN B 1 88  ? 13.818  42.339 29.280 1.000 23.874  0 69  ASN B CB    1 ? ? 
ATOM   2560 C CG    . ASN B 1 88  ? 15.158  41.923 29.827 1.000 27.994  0 69  ASN B CG    1 ? ? 
ATOM   2561 O OD1   . ASN B 1 88  ? 16.182  42.505 29.459 1.000 31.065  0 69  ASN B OD1   1 ? ? 
ATOM   2562 N ND2   . ASN B 1 88  ? 15.150  40.941 30.709 1.000 28.664  0 69  ASN B ND2   1 ? ? 
ATOM   2563 N N     . MET B 1 89  ? 12.523  42.690 25.897 1.000 20.966  0 70  MET B N     1 ? ? 
ATOM   2564 C CA    . MET B 1 89  ? 11.717  41.936 24.957 1.000 22.194  0 70  MET B CA    1 ? ? 
ATOM   2565 C C     . MET B 1 89  ? 12.607  41.089 24.050 1.000 22.072  0 70  MET B C     1 ? ? 
ATOM   2566 O O     . MET B 1 89  ? 12.261  39.967 23.713 1.000 22.322  0 70  MET B O     1 ? ? 
ATOM   2567 C CB    . MET B 1 89  ? 10.841  42.884 24.136 1.000 21.440  0 70  MET B CB    1 ? ? 
ATOM   2568 C CG    . MET B 1 89  ? 9.709   43.412 24.976 1.000 21.959  0 70  MET B CG    1 ? ? 
ATOM   2569 S SD    . MET B 1 89  ? 8.864   44.817 24.289 1.000 23.641  0 70  MET B SD    1 ? ? 
ATOM   2570 C CE    . MET B 1 89  ? 7.591   45.096 25.513 1.000 23.356  0 70  MET B CE    1 ? ? 
ATOM   2571 N N     . VAL B 1 90  ? 13.762  41.638 23.677 1.000 20.535  0 71  VAL B N     1 ? ? 
ATOM   2572 C CA    . VAL B 1 90  ? 14.820  40.876 23.042 1.000 21.096  0 71  VAL B CA    1 ? ? 
ATOM   2573 C C     . VAL B 1 90  ? 16.132  41.290 23.710 1.000 21.570  0 71  VAL B C     1 ? ? 
ATOM   2574 O O     . VAL B 1 90  ? 16.337  42.459 24.024 1.000 22.037  0 71  VAL B O     1 ? ? 
ATOM   2575 C CB    . VAL B 1 90  ? 14.851  41.065 21.510 1.000 20.868  0 71  VAL B CB    1 ? ? 
ATOM   2576 C CG1   . VAL B 1 90  ? 15.032  42.523 21.100 1.000 19.585  0 71  VAL B CG1   1 ? ? 
ATOM   2577 C CG2   . VAL B 1 90  ? 15.885  40.178 20.842 1.000 19.318  0 71  VAL B CG2   1 ? ? 
ATOM   2578 N N     . ILE B 1 91  ? 16.998  40.312 23.974 1.000 21.765  0 72  ILE B N     1 ? ? 
ATOM   2579 C CA    . ILE B 1 91  ? 18.256  40.561 24.656 1.000 23.071  0 72  ILE B CA    1 ? ? 
ATOM   2580 C C     . ILE B 1 91  ? 19.378  40.139 23.729 1.000 23.337  0 72  ILE B C     1 ? ? 
ATOM   2581 O O     . ILE B 1 91  ? 19.796  38.990 23.729 1.000 24.210  0 72  ILE B O     1 ? ? 
ATOM   2582 C CB    . ILE B 1 91  ? 18.311  39.821 26.004 1.000 23.940  0 72  ILE B CB    1 ? ? 
ATOM   2583 C CG1   . ILE B 1 91  ? 17.217  40.355 26.941 1.000 23.095  0 72  ILE B CG1   1 ? ? 
ATOM   2584 C CG2   . ILE B 1 91  ? 19.685  39.961 26.644 1.000 22.474  0 72  ILE B CG2   1 ? ? 
ATOM   2585 C CD1   . ILE B 1 91  ? 16.423  39.301 27.641 1.000 21.162  0 72  ILE B CD1   1 ? ? 
ATOM   2586 N N     . PRO B 1 92  ? 19.880  41.062 22.893 1.000 24.204  0 73  PRO B N     1 ? ? 
ATOM   2587 C CA    . PRO B 1 92  ? 20.940  40.728 21.946 1.000 24.741  0 73  PRO B CA    1 ? ? 
ATOM   2588 C C     . PRO B 1 92  ? 22.179  40.300 22.707 1.000 25.838  0 73  PRO B C     1 ? ? 
ATOM   2589 O O     . PRO B 1 92  ? 22.556  40.939 23.681 1.000 25.485  0 73  PRO B O     1 ? ? 
ATOM   2590 C CB    . PRO B 1 92  ? 21.131  42.016 21.156 1.000 24.696  0 73  PRO B CB    1 ? ? 
ATOM   2591 C CG    . PRO B 1 92  ? 19.816  42.735 21.329 1.000 23.859  0 73  PRO B CG    1 ? ? 
ATOM   2592 C CD    . PRO B 1 92  ? 19.427  42.452 22.767 1.000 24.241  0 73  PRO B CD    1 ? ? 
ATOM   2593 N N     . GLU B 1 93  ? 22.742  39.166 22.280 1.000 28.544  0 74  GLU B N     1 ? ? 
ATOM   2594 C CA    . GLU B 1 93  ? 23.919  38.577 22.889 1.000 29.007  0 74  GLU B CA    1 ? ? 
ATOM   2595 C C     . GLU B 1 93  ? 24.627  37.728 21.850 1.000 29.134  0 74  GLU B C     1 ? ? 
ATOM   2596 O O     . GLU B 1 93  ? 24.017  37.359 20.852 1.000 29.703  0 74  GLU B O     1 ? ? 
ATOM   2597 C CB    . GLU B 1 93  ? 23.520  37.730 24.094 1.000 30.607  0 74  GLU B CB    1 ? ? 
ATOM   2598 C CG    . GLU B 1 93  ? 22.536  36.625 23.775 1.000 34.583  0 74  GLU B CG    1 ? ? 
ATOM   2599 C CD    . GLU B 1 93  ? 21.983  36.002 25.047 1.000 37.162  0 74  GLU B CD    1 ? ? 
ATOM   2600 O OE1   . GLU B 1 93  ? 20.924  35.432 24.986 1.000 35.405  0 74  GLU B OE1   1 ? ? 
ATOM   2601 O OE2   . GLU B 1 93  ? 22.620  36.109 26.116 1.000 41.853  0 74  GLU B OE2   1 ? ? 
ATOM   2602 N N     . GLY B 1 94  ? 25.913  37.449 22.085 1.000 28.363  0 75  GLY B N     1 ? ? 
ATOM   2603 C CA    . GLY B 1 94  ? 26.713  36.596 21.221 1.000 27.495  0 75  GLY B CA    1 ? ? 
ATOM   2604 C C     . GLY B 1 94  ? 26.703  37.036 19.758 1.000 26.982  0 75  GLY B C     1 ? ? 
ATOM   2605 O O     . GLY B 1 94  ? 26.856  38.219 19.455 1.000 26.857  0 75  GLY B O     1 ? ? 
ATOM   2606 N N     . ARG B 1 95  ? 26.501  36.065 18.856 1.000 27.418  0 76  ARG B N     1 ? ? 
ATOM   2607 C CA    . ARG B 1 95  ? 26.462  36.329 17.427 1.000 28.763  0 76  ARG B CA    1 ? ? 
ATOM   2608 C C     . ARG B 1 95  ? 25.077  36.838 17.024 1.000 27.849  0 76  ARG B C     1 ? ? 
ATOM   2609 O O     . ARG B 1 95  ? 24.061  36.157 17.215 1.000 27.839  0 76  ARG B O     1 ? ? 
ATOM   2610 C CB    . ARG B 1 95  ? 26.872  35.072 16.655 1.000 30.064  0 76  ARG B CB    1 ? ? 
ATOM   2611 C CG    . ARG B 1 95  ? 26.918  35.259 15.148 1.000 33.183  0 76  ARG B CG    1 ? ? 
ATOM   2612 C CD    . ARG B 1 95  ? 27.331  33.971 14.466 1.000 38.082  0 76  ARG B CD    1 ? ? 
ATOM   2613 N NE    . ARG B 1 95  ? 27.519  34.190 13.032 1.000 45.949  0 76  ARG B NE    1 ? ? 
ATOM   2614 C CZ    . ARG B 1 95  ? 26.757  33.586 12.104 1.000 46.348  0 76  ARG B CZ    1 ? ? 
ATOM   2615 N NH1   . ARG B 1 95  ? 25.805  32.702 12.453 1.000 46.706  0 76  ARG B NH1   1 ? ? 
ATOM   2616 N NH2   . ARG B 1 95  ? 26.948  33.815 10.820 1.000 46.959  0 76  ARG B NH2   1 ? ? 
ATOM   2617 N N     . VAL B 1 96  ? 25.037  38.056 16.482 1.000 26.138  0 77  VAL B N     1 ? ? 
ATOM   2618 C CA    . VAL B 1 96  ? 23.777  38.687 16.122 1.000 24.735  0 77  VAL B CA    1 ? ? 
ATOM   2619 C C     . VAL B 1 96  ? 23.688  38.698 14.598 1.000 25.199  0 77  VAL B C     1 ? ? 
ATOM   2620 O O     . VAL B 1 96  ? 24.620  39.168 13.940 1.000 25.300  0 77  VAL B O     1 ? ? 
ATOM   2621 C CB    . VAL B 1 96  ? 23.692  40.109 16.717 1.000 22.206  0 77  VAL B CB    1 ? ? 
ATOM   2622 C CG1   . VAL B 1 96  ? 22.489  40.890 16.219 1.000 20.137  0 77  VAL B CG1   1 ? ? 
ATOM   2623 C CG2   . VAL B 1 96  ? 23.723  40.075 18.237 1.000 21.718  0 77  VAL B CG2   1 ? ? 
ATOM   2624 N N     . ILE B 1 97  ? 22.591  38.152 14.053 1.000 25.251  0 78  ILE B N     1 ? ? 
ATOM   2625 C CA    . ILE B 1 97  ? 22.278  38.318 12.644 1.000 26.766  0 78  ILE B CA    1 ? ? 
ATOM   2626 C C     . ILE B 1 97  ? 21.174  39.368 12.492 1.000 28.769  0 78  ILE B C     1 ? ? 
ATOM   2627 O O     . ILE B 1 97  ? 20.163  39.324 13.195 1.000 29.397  0 78  ILE B O     1 ? ? 
ATOM   2628 C CB    . ILE B 1 97  ? 21.867  36.970 12.028 1.000 27.402  0 78  ILE B CB    1 ? ? 
ATOM   2629 C CG1   . ILE B 1 97  ? 22.950  35.908 12.190 1.000 28.243  0 78  ILE B CG1   1 ? ? 
ATOM   2630 C CG2   . ILE B 1 97  ? 21.509  37.126 10.563 1.000 26.579  0 78  ILE B CG2   1 ? ? 
ATOM   2631 C CD1   . ILE B 1 97  ? 24.110  36.104 11.225 1.000 27.908  0 78  ILE B CD1   1 ? ? 
ATOM   2632 N N     . ASP B 1 98  ? 21.373  40.303 11.556 1.000 29.655  0 79  ASP B N     1 ? ? 
ATOM   2633 C CA    . ASP B 1 98  ? 20.435  41.386 11.300 1.000 28.834  0 79  ASP B CA    1 ? ? 
ATOM   2634 C C     . ASP B 1 98  ? 19.960  41.308 9.849  1.000 27.991  0 79  ASP B C     1 ? ? 
ATOM   2635 O O     . ASP B 1 98  ? 20.603  41.854 8.962  1.000 25.984  0 79  ASP B O     1 ? ? 
ATOM   2636 C CB    . ASP B 1 98  ? 21.081  42.739 11.613 1.000 30.176  0 79  ASP B CB    1 ? ? 
ATOM   2637 C CG    . ASP B 1 98  ? 20.162  43.921 11.401 1.000 32.760  0 79  ASP B CG    1 ? ? 
ATOM   2638 O OD1   . ASP B 1 98  ? 18.968  43.688 11.236 1.000 36.378  0 79  ASP B OD1   1 ? ? 
ATOM   2639 O OD2   . ASP B 1 98  ? 20.655  45.071 11.398 1.000 35.708  0 79  ASP B OD2   1 ? ? 
ATOM   2640 N N     . LEU B 1 99  ? 18.812  40.655 9.623  1.000 27.078  0 80  LEU B N     1 ? ? 
ATOM   2641 C CA    . LEU B 1 99  ? 18.297  40.421 8.276  1.000 27.145  0 80  LEU B CA    1 ? ? 
ATOM   2642 C C     . LEU B 1 99  ? 17.488  41.632 7.815  1.000 29.125  0 80  LEU B C     1 ? ? 
ATOM   2643 O O     . LEU B 1 99  ? 16.486  41.992 8.440  1.000 31.271  0 80  LEU B O     1 ? ? 
ATOM   2644 C CB    . LEU B 1 99  ? 17.408  39.176 8.271  1.000 25.573  0 80  LEU B CB    1 ? ? 
ATOM   2645 C CG    . LEU B 1 99  ? 18.028  37.861 8.736  1.000 24.433  0 80  LEU B CG    1 ? ? 
ATOM   2646 C CD1   . LEU B 1 99  ? 16.983  36.744 8.662  1.000 25.657  0 80  LEU B CD1   1 ? ? 
ATOM   2647 C CD2   . LEU B 1 99  ? 19.246  37.491 7.905  1.000 23.105  0 80  LEU B CD2   1 ? ? 
ATOM   2648 N N     . GLY B 1 100 ? 17.893  42.203 6.676  1.000 29.390  0 81  GLY B N     1 ? ? 
ATOM   2649 C CA    . GLY B 1 100 ? 17.325  43.445 6.179  1.000 27.827  0 81  GLY B CA    1 ? ? 
ATOM   2650 C C     . GLY B 1 100 ? 17.882  44.650 6.934  1.000 28.168  0 81  GLY B C     1 ? ? 
ATOM   2651 O O     . GLY B 1 100 ? 17.130  45.546 7.310  1.000 30.159  0 81  GLY B O     1 ? ? 
ATOM   2652 N N     . CYS B 1 101 ? 19.204  44.679 7.132  1.000 27.645  0 82  CYS B N     1 ? ? 
ATOM   2653 C CA    . CYS B 1 101 ? 19.846  45.685 7.967  1.000 27.558  0 82  CYS B CA    1 ? ? 
ATOM   2654 C C     . CYS B 1 101 ? 19.701  47.091 7.372  1.000 27.116  0 82  CYS B C     1 ? ? 
ATOM   2655 O O     . CYS B 1 101 ? 19.663  48.085 8.118  1.000 25.277  0 82  CYS B O     1 ? ? 
ATOM   2656 C CB    . CYS B 1 101 ? 21.313  45.346 8.229  1.000 27.370  0 82  CYS B CB    1 ? ? 
ATOM   2657 S SG    . CYS B 1 101 ? 22.357  45.351 6.747  1.000 30.624  0 82  CYS B SG    1 ? ? 
ATOM   2658 N N     . GLY B 1 102 ? 19.599  47.175 6.034  1.000 27.821  0 83  GLY B N     1 ? ? 
ATOM   2659 C CA    . GLY B 1 102 ? 19.548  48.474 5.379  1.000 26.708  0 83  GLY B CA    1 ? ? 
ATOM   2660 C C     . GLY B 1 102 ? 20.767  49.305 5.771  1.000 26.794  0 83  GLY B C     1 ? ? 
ATOM   2661 O O     . GLY B 1 102 ? 21.892  48.826 5.663  1.000 27.216  0 83  GLY B O     1 ? ? 
ATOM   2662 N N     . ARG B 1 103 ? 20.542  50.532 6.252  1.000 26.817  0 84  ARG B N     1 ? ? 
ATOM   2663 C CA    . ARG B 1 103 ? 21.635  51.436 6.589  1.000 27.783  0 84  ARG B CA    1 ? ? 
ATOM   2664 C C     . ARG B 1 103 ? 22.454  50.902 7.763  1.000 27.737  0 84  ARG B C     1 ? ? 
ATOM   2665 O O     . ARG B 1 103 ? 23.669  51.129 7.850  1.000 26.254  0 84  ARG B O     1 ? ? 
ATOM   2666 C CB    . ARG B 1 103 ? 21.077  52.816 6.917  1.000 28.930  0 84  ARG B CB    1 ? ? 
ATOM   2667 C CG    . ARG B 1 103 ? 20.610  53.515 5.653  1.000 32.497  0 84  ARG B CG    1 ? ? 
ATOM   2668 C CD    . ARG B 1 103 ? 19.680  54.689 5.736  1.000 34.072  0 84  ARG B CD    1 ? ? 
ATOM   2669 N NE    . ARG B 1 103 ? 20.321  55.772 6.440  1.000 40.140  0 84  ARG B NE    1 ? ? 
ATOM   2670 C CZ    . ARG B 1 103 ? 21.053  56.737 5.888  1.000 41.531  0 84  ARG B CZ    1 ? ? 
ATOM   2671 N NH1   . ARG B 1 103 ? 21.372  56.664 4.607  1.000 38.113  0 84  ARG B NH1   1 ? ? 
ATOM   2672 N NH2   . ARG B 1 103 ? 21.549  57.684 6.679  1.000 43.098  0 84  ARG B NH2   1 ? ? 
ATOM   2673 N N     . GLY B 1 104 ? 21.772  50.191 8.666  1.000 25.610  0 85  GLY B N     1 ? ? 
ATOM   2674 C CA    . GLY B 1 104 ? 22.472  49.466 9.708  1.000 23.696  0 85  GLY B CA    1 ? ? 
ATOM   2675 C C     . GLY B 1 104 ? 22.114  49.889 11.125 1.000 22.310  0 85  GLY B C     1 ? ? 
ATOM   2676 O O     . GLY B 1 104 ? 22.870  49.582 12.038 1.000 23.457  0 85  GLY B O     1 ? ? 
ATOM   2677 N N     . GLY B 1 105 ? 20.956  50.527 11.302 1.000 20.625  0 86  GLY B N     1 ? ? 
ATOM   2678 C CA    . GLY B 1 105 ? 20.515  51.034 12.594 1.000 19.540  0 86  GLY B CA    1 ? ? 
ATOM   2679 C C     . GLY B 1 105 ? 20.486  49.986 13.700 1.000 18.736  0 86  GLY B C     1 ? ? 
ATOM   2680 O O     . GLY B 1 105 ? 20.942  50.246 14.803 1.000 19.398  0 86  GLY B O     1 ? ? 
ATOM   2681 N N     . TRP B 1 106 ? 19.947  48.807 13.403 1.000 18.649  0 87  TRP B N     1 ? ? 
ATOM   2682 C CA    . TRP B 1 106 ? 19.866  47.759 14.408 1.000 18.945  0 87  TRP B CA    1 ? ? 
ATOM   2683 C C     . TRP B 1 106 ? 21.248  47.193 14.714 1.000 19.619  0 87  TRP B C     1 ? ? 
ATOM   2684 O O     . TRP B 1 106 ? 21.535  46.866 15.862 1.000 21.659  0 87  TRP B O     1 ? ? 
ATOM   2685 C CB    . TRP B 1 106 ? 18.916  46.649 13.968 1.000 16.990  0 87  TRP B CB    1 ? ? 
ATOM   2686 C CG    . TRP B 1 106 ? 17.480  47.033 14.098 1.000 16.508  0 87  TRP B CG    1 ? ? 
ATOM   2687 C CD1   . TRP B 1 106 ? 16.960  48.293 14.201 1.000 16.971  0 87  TRP B CD1   1 ? ? 
ATOM   2688 C CD2   . TRP B 1 106 ? 16.359  46.134 14.083 1.000 16.155  0 87  TRP B CD2   1 ? ? 
ATOM   2689 N NE1   . TRP B 1 106 ? 15.591  48.238 14.261 1.000 16.432  0 87  TRP B NE1   1 ? ? 
ATOM   2690 C CE2   . TRP B 1 106 ? 15.194  46.927 14.192 1.000 15.756  0 87  TRP B CE2   1 ? ? 
ATOM   2691 C CE3   . TRP B 1 106 ? 16.228  44.741 13.989 1.000 15.801  0 87  TRP B CE3   1 ? ? 
ATOM   2692 C CZ2   . TRP B 1 106 ? 13.918  46.369 14.209 1.000 15.160  0 87  TRP B CZ2   1 ? ? 
ATOM   2693 C CZ3   . TRP B 1 106 ? 14.964  44.190 13.989 1.000 15.097  0 87  TRP B CZ3   1 ? ? 
ATOM   2694 C CH2   . TRP B 1 106 ? 13.830  44.996 14.109 1.000 15.318  0 87  TRP B CH2   1 ? ? 
ATOM   2695 N N     . SER B 1 107 ? 22.086  47.066 13.683 1.000 20.104  0 88  SER B N     1 ? ? 
ATOM   2696 C CA    . SER B 1 107 ? 23.398  46.458 13.826 1.000 20.211  0 88  SER B CA    1 ? ? 
ATOM   2697 C C     . SER B 1 107 ? 24.310  47.333 14.675 1.000 19.566  0 88  SER B C     1 ? ? 
ATOM   2698 O O     . SER B 1 107 ? 24.990  46.845 15.560 1.000 18.609  0 88  SER B O     1 ? ? 
ATOM   2699 C CB    . SER B 1 107 ? 24.002  46.195 12.485 1.000 19.817  0 88  SER B CB    1 ? ? 
ATOM   2700 O OG    . SER B 1 107 ? 23.395  45.065 11.874 1.000 21.096  0 88  SER B OG    1 ? ? 
ATOM   2701 N N     . TYR B 1 108 ? 24.343  48.634 14.387 1.000 20.409  0 89  TYR B N     1 ? ? 
ATOM   2702 C CA    . TYR B 1 108 ? 25.207  49.546 15.111 1.000 20.897  0 89  TYR B CA    1 ? ? 
ATOM   2703 C C     . TYR B 1 108 ? 24.775  49.677 16.569 1.000 20.530  0 89  TYR B C     1 ? ? 
ATOM   2704 O O     . TYR B 1 108 ? 25.618  49.841 17.451 1.000 19.111  0 89  TYR B O     1 ? ? 
ATOM   2705 C CB    . TYR B 1 108 ? 25.225  50.908 14.424 1.000 21.544  0 89  TYR B CB    1 ? ? 
ATOM   2706 C CG    . TYR B 1 108 ? 26.059  50.896 13.176 1.000 23.103  0 89  TYR B CG    1 ? ? 
ATOM   2707 C CD1   . TYR B 1 108 ? 27.379  50.497 13.216 1.000 23.100  0 89  TYR B CD1   1 ? ? 
ATOM   2708 C CD2   . TYR B 1 108 ? 25.534  51.288 11.952 1.000 24.702  0 89  TYR B CD2   1 ? ? 
ATOM   2709 C CE1   . TYR B 1 108 ? 28.163  50.477 12.074 1.000 23.282  0 89  TYR B CE1   1 ? ? 
ATOM   2710 C CE2   . TYR B 1 108 ? 26.292  51.268 10.794 1.000 24.845  0 89  TYR B CE2   1 ? ? 
ATOM   2711 C CZ    . TYR B 1 108 ? 27.616  50.859 10.860 1.000 24.507  0 89  TYR B CZ    1 ? ? 
ATOM   2712 O OH    . TYR B 1 108 ? 28.390  50.858 9.741  1.000 25.536  0 89  TYR B OH    1 ? ? 
ATOM   2713 N N     . TYR B 1 109 ? 23.463  49.632 16.808 1.000 19.444  0 90  TYR B N     1 ? ? 
ATOM   2714 C CA    . TYR B 1 109 ? 22.969  49.717 18.168 1.000 18.780  0 90  TYR B CA    1 ? ? 
ATOM   2715 C C     . TYR B 1 109 ? 23.426  48.502 18.965 1.000 18.669  0 90  TYR B C     1 ? ? 
ATOM   2716 O O     . TYR B 1 109 ? 23.981  48.661 20.056 1.000 18.401  0 90  TYR B O     1 ? ? 
ATOM   2717 C CB    . TYR B 1 109 ? 21.455  49.900 18.210 1.000 18.842  0 90  TYR B CB    1 ? ? 
ATOM   2718 C CG    . TYR B 1 109 ? 20.901  49.749 19.603 1.000 19.726  0 90  TYR B CG    1 ? ? 
ATOM   2719 C CD1   . TYR B 1 109 ? 21.094  50.719 20.576 1.000 19.522  0 90  TYR B CD1   1 ? ? 
ATOM   2720 C CD2   . TYR B 1 109 ? 20.207  48.606 19.965 1.000 19.899  0 90  TYR B CD2   1 ? ? 
ATOM   2721 C CE1   . TYR B 1 109 ? 20.593  50.576 21.863 1.000 19.020  0 90  TYR B CE1   1 ? ? 
ATOM   2722 C CE2   . TYR B 1 109 ? 19.716  48.436 21.251 1.000 19.907  0 90  TYR B CE2   1 ? ? 
ATOM   2723 C CZ    . TYR B 1 109 ? 19.932  49.412 22.207 1.000 19.049  0 90  TYR B CZ    1 ? ? 
ATOM   2724 O OH    . TYR B 1 109 ? 19.469  49.264 23.476 1.000 19.726  0 90  TYR B OH    1 ? ? 
ATOM   2725 N N     . CYS B 1 110 ? 23.214  47.297 18.410 1.000 18.452  0 91  CYS B N     1 ? ? 
ATOM   2726 C CA    . CYS B 1 110 ? 23.590  46.072 19.111 1.000 18.228  0 91  CYS B CA    1 ? ? 
ATOM   2727 C C     . CYS B 1 110 ? 25.104  46.026 19.329 1.000 18.472  0 91  CYS B C     1 ? ? 
ATOM   2728 O O     . CYS B 1 110 ? 25.578  45.424 20.290 1.000 17.394  0 91  CYS B O     1 ? ? 
ATOM   2729 C CB    . CYS B 1 110 ? 23.218  44.815 18.337 1.000 18.435  0 91  CYS B CB    1 ? ? 
ATOM   2730 S SG    . CYS B 1 110 ? 21.441  44.545 18.187 1.000 21.061  0 91  CYS B SG    1 ? ? 
ATOM   2731 N N     . ALA B 1 111 ? 25.865  46.690 18.453 1.000 19.037  0 92  ALA B N     1 ? ? 
ATOM   2732 C CA    . ALA B 1 111 ? 27.308  46.558 18.490 1.000 21.067  0 92  ALA B CA    1 ? ? 
ATOM   2733 C C     . ALA B 1 111 ? 27.875  47.173 19.772 1.000 21.974  0 92  ALA B C     1 ? ? 
ATOM   2734 O O     . ALA B 1 111 ? 28.998  46.866 20.155 1.000 22.151  0 92  ALA B O     1 ? ? 
ATOM   2735 C CB    . ALA B 1 111 ? 27.906  47.193 17.263 1.000 22.268  0 92  ALA B CB    1 ? ? 
ATOM   2736 N N     . GLY B 1 112 ? 27.095  48.021 20.450 1.000 21.358  0 93  GLY B N     1 ? ? 
ATOM   2737 C CA    . GLY B 1 112 ? 27.569  48.648 21.669 1.000 21.981  0 93  GLY B CA    1 ? ? 
ATOM   2738 C C     . GLY B 1 112 ? 27.055  47.975 22.936 1.000 22.268  0 93  GLY B C     1 ? ? 
ATOM   2739 O O     . GLY B 1 112 ? 27.422  48.413 24.022 1.000 21.545  0 93  GLY B O     1 ? ? 
ATOM   2740 N N     . LEU B 1 113 ? 26.285  46.887 22.786 1.000 22.877  0 94  LEU B N     1 ? ? 
ATOM   2741 C CA    . LEU B 1 113 ? 25.741  46.167 23.931 1.000 24.336  0 94  LEU B CA    1 ? ? 
ATOM   2742 C C     . LEU B 1 113 ? 26.739  45.147 24.482 1.000 26.368  0 94  LEU B C     1 ? ? 
ATOM   2743 O O     . LEU B 1 113 ? 27.343  44.383 23.734 1.000 24.941  0 94  LEU B O     1 ? ? 
ATOM   2744 C CB    . LEU B 1 113 ? 24.441  45.469 23.538 1.000 22.377  0 94  LEU B CB    1 ? ? 
ATOM   2745 C CG    . LEU B 1 113 ? 23.358  46.379 22.982 1.000 21.767  0 94  LEU B CG    1 ? ? 
ATOM   2746 C CD1   . LEU B 1 113 ? 22.117  45.576 22.668 1.000 20.834  0 94  LEU B CD1   1 ? ? 
ATOM   2747 C CD2   . LEU B 1 113 ? 23.011  47.482 23.962 1.000 22.897  0 94  LEU B CD2   1 ? ? 
ATOM   2748 N N     . LYS B 1 114 ? 26.828  45.083 25.812 1.000 29.573  0 95  LYS B N     1 ? ? 
ATOM   2749 C CA    . LYS B 1 114 ? 27.855  44.323 26.505 1.000 33.064  0 95  LYS B CA    1 ? ? 
ATOM   2750 C C     . LYS B 1 114 ? 27.876  42.855 26.066 1.000 32.432  0 95  LYS B C     1 ? ? 
ATOM   2751 O O     . LYS B 1 114 ? 28.940  42.296 25.825 1.000 30.953  0 95  LYS B O     1 ? ? 
ATOM   2752 C CB    . LYS B 1 114 ? 27.681  44.475 28.027 1.000 37.697  0 95  LYS B CB    1 ? ? 
ATOM   2753 C CG    . LYS B 1 114 ? 26.366  45.073 28.555 1.000 41.062  0 95  LYS B CG    1 ? ? 
ATOM   2754 C CD    . LYS B 1 114 ? 26.461  46.478 29.166 1.000 42.245  0 95  LYS B CD    1 ? ? 
ATOM   2755 C CE    . LYS B 1 114 ? 26.158  46.512 30.649 1.000 40.762  0 95  LYS B CE    1 ? ? 
ATOM   2756 N NZ    . LYS B 1 114 ? 26.253  45.152 31.225 1.000 41.826  0 95  LYS B NZ    1 ? ? 
ATOM   2757 N N     . LYS B 1 115 ? 26.700  42.215 25.990 1.000 30.220  0 96  LYS B N     1 ? ? 
ATOM   2758 C CA    . LYS B 1 115 ? 26.665  40.778 25.768 1.000 29.658  0 96  LYS B CA    1 ? ? 
ATOM   2759 C C     . LYS B 1 115 ? 26.920  40.383 24.314 1.000 28.507  0 96  LYS B C     1 ? ? 
ATOM   2760 O O     . LYS B 1 115 ? 27.054  39.194 24.024 1.000 28.420  0 96  LYS B O     1 ? ? 
ATOM   2761 C CB    . LYS B 1 115 ? 25.327  40.188 26.210 1.000 28.749  0 96  LYS B CB    1 ? ? 
ATOM   2762 C CG    . LYS B 1 115 ? 25.045  40.332 27.692 1.000 29.214  0 96  LYS B CG    1 ? ? 
ATOM   2763 C CD    . LYS B 1 115 ? 23.842  39.592 28.126 1.000 31.982  0 96  LYS B CD    1 ? ? 
ATOM   2764 C CE    . LYS B 1 115 ? 22.983  40.364 29.106 1.000 34.059  0 96  LYS B CE    1 ? ? 
ATOM   2765 N NZ    . LYS B 1 115 ? 22.336  39.428 30.054 1.000 33.884  0 96  LYS B NZ    1 ? ? 
ATOM   2766 N N     . VAL B 1 116 ? 26.979  41.359 23.406 1.000 27.742  0 97  VAL B N     1 ? ? 
ATOM   2767 C CA    . VAL B 1 116 ? 27.078  41.072 21.986 1.000 27.970  0 97  VAL B CA    1 ? ? 
ATOM   2768 C C     . VAL B 1 116 ? 28.549  40.939 21.612 1.000 29.561  0 97  VAL B C     1 ? ? 
ATOM   2769 O O     . VAL B 1 116 ? 29.380  41.766 21.996 1.000 31.277  0 97  VAL B O     1 ? ? 
ATOM   2770 C CB    . VAL B 1 116 ? 26.424  42.188 21.156 1.000 27.605  0 97  VAL B CB    1 ? ? 
ATOM   2771 C CG1   . VAL B 1 116 ? 26.723  42.075 19.668 1.000 27.135  0 97  VAL B CG1   1 ? ? 
ATOM   2772 C CG2   . VAL B 1 116 ? 24.941  42.297 21.407 1.000 26.893  0 97  VAL B CG2   1 ? ? 
ATOM   2773 N N     . THR B 1 117 ? 28.838  39.902 20.818 1.000 28.618  0 98  THR B N     1 ? ? 
ATOM   2774 C CA    . THR B 1 117 ? 30.204  39.572 20.450 1.000 29.461  0 98  THR B CA    1 ? ? 
ATOM   2775 C C     . THR B 1 117 ? 30.462  39.814 18.957 1.000 28.795  0 98  THR B C     1 ? ? 
ATOM   2776 O O     . THR B 1 117 ? 31.598  39.984 18.538 1.000 29.954  0 98  THR B O     1 ? ? 
ATOM   2777 C CB    . THR B 1 117 ? 30.546  38.140 20.899 1.000 30.387  0 98  THR B CB    1 ? ? 
ATOM   2778 O OG1   . THR B 1 117 ? 29.835  37.194 20.097 1.000 30.584  0 98  THR B OG1   1 ? ? 
ATOM   2779 C CG2   . THR B 1 117 ? 30.229  37.867 22.355 1.000 30.755  0 98  THR B CG2   1 ? ? 
ATOM   2780 N N     . GLU B 1 118 ? 29.422  39.773 18.132 1.000 28.835  0 99  GLU B N     1 ? ? 
ATOM   2781 C CA    . GLU B 1 118 ? 29.571  39.853 16.688 1.000 30.688  0 99  GLU B CA    1 ? ? 
ATOM   2782 C C     . GLU B 1 118 ? 28.223  40.231 16.095 1.000 27.873  0 99  GLU B C     1 ? ? 
ATOM   2783 O O     . GLU B 1 118 ? 27.169  39.773 16.552 1.000 26.928  0 99  GLU B O     1 ? ? 
ATOM   2784 C CB    . GLU B 1 118 ? 29.994  38.499 16.106 1.000 35.806  0 99  GLU B CB    1 ? ? 
ATOM   2785 C CG    . GLU B 1 118 ? 30.183  38.475 14.595 1.000 42.219  0 99  GLU B CG    1 ? ? 
ATOM   2786 C CD    . GLU B 1 118 ? 30.399  37.067 14.089 1.000 47.993  0 99  GLU B CD    1 ? ? 
ATOM   2787 O OE1   . GLU B 1 118 ? 30.170  36.832 12.933 1.000 51.506  0 99  GLU B OE1   1 ? ? 
ATOM   2788 O OE2   . GLU B 1 118 ? 30.743  36.200 14.908 1.000 52.418  0 99  GLU B OE2   1 ? ? 
ATOM   2789 N N     . VAL B 1 119 ? 28.280  41.081 15.072 1.000 26.758  0 100 VAL B N     1 ? ? 
ATOM   2790 C CA    . VAL B 1 119 ? 27.080  41.518 14.380 1.000 27.864  0 100 VAL B CA    1 ? ? 
ATOM   2791 C C     . VAL B 1 119 ? 27.274  41.358 12.873 1.000 29.658  0 100 VAL B C     1 ? ? 
ATOM   2792 O O     . VAL B 1 119 ? 28.166  41.979 12.290 1.000 32.759  0 100 VAL B O     1 ? ? 
ATOM   2793 C CB    . VAL B 1 119 ? 26.721  42.975 14.729 1.000 25.415  0 100 VAL B CB    1 ? ? 
ATOM   2794 C CG1   . VAL B 1 119 ? 25.418  43.381 14.075 1.000 25.504  0 100 VAL B CG1   1 ? ? 
ATOM   2795 C CG2   . VAL B 1 119 ? 26.674  43.228 16.228 1.000 25.338  0 100 VAL B CG2   1 ? ? 
ATOM   2796 N N     . ARG B 1 120 ? 26.414  40.542 12.252 1.000 29.370  0 101 ARG B N     1 ? ? 
ATOM   2797 C CA    . ARG B 1 120 ? 26.441  40.360 10.808 1.000 30.374  0 101 ARG B CA    1 ? ? 
ATOM   2798 C C     . ARG B 1 120 ? 25.116  40.836 10.226 1.000 28.423  0 101 ARG B C     1 ? ? 
ATOM   2799 O O     . ARG B 1 120 ? 24.065  40.273 10.509 1.000 26.414  0 101 ARG B O     1 ? ? 
ATOM   2800 C CB    . ARG B 1 120 ? 26.679  38.902 10.431 1.000 32.348  0 101 ARG B CB    1 ? ? 
ATOM   2801 C CG    . ARG B 1 120 ? 27.925  38.341 11.063 1.000 35.401  0 101 ARG B CG    1 ? ? 
ATOM   2802 C CD    . ARG B 1 120 ? 29.156  38.273 10.223 1.000 41.831  0 101 ARG B CD    1 ? ? 
ATOM   2803 N NE    . ARG B 1 120 ? 29.089  37.024 9.519  1.000 44.121  0 101 ARG B NE    1 ? ? 
ATOM   2804 C CZ    . ARG B 1 120 ? 29.592  36.826 8.326  1.000 42.053  0 101 ARG B CZ    1 ? ? 
ATOM   2805 N NH1   . ARG B 1 120 ? 30.232  37.796 7.698  1.000 38.534  0 101 ARG B NH1   1 ? ? 
ATOM   2806 N NH2   . ARG B 1 120 ? 29.443  35.632 7.777  1.000 38.925  0 101 ARG B NH2   1 ? ? 
ATOM   2807 N N     . GLY B 1 121 ? 25.198  41.888 9.412  1.000 28.143  0 102 GLY B N     1 ? ? 
ATOM   2808 C CA    . GLY B 1 121 ? 24.039  42.488 8.778  1.000 29.772  0 102 GLY B CA    1 ? ? 
ATOM   2809 C C     . GLY B 1 121 ? 23.998  42.180 7.289  1.000 32.682  0 102 GLY B C     1 ? ? 
ATOM   2810 O O     . GLY B 1 121 ? 25.032  42.209 6.615  1.000 33.454  0 102 GLY B O     1 ? ? 
ATOM   2811 N N     . TYR B 1 122 ? 22.788  41.851 6.812  1.000 33.369  0 103 TYR B N     1 ? ? 
ATOM   2812 C CA    . TYR B 1 122 ? 22.544  41.482 5.430  1.000 31.963  0 103 TYR B CA    1 ? ? 
ATOM   2813 C C     . TYR B 1 122 ? 21.409  42.331 4.879  1.000 31.531  0 103 TYR B C     1 ? ? 
ATOM   2814 O O     . TYR B 1 122 ? 20.332  42.398 5.454  1.000 32.148  0 103 TYR B O     1 ? ? 
ATOM   2815 C CB    . TYR B 1 122 ? 22.110  40.019 5.328  1.000 32.099  0 103 TYR B CB    1 ? ? 
ATOM   2816 C CG    . TYR B 1 122 ? 23.118  39.028 5.844  1.000 33.398  0 103 TYR B CG    1 ? ? 
ATOM   2817 C CD1   . TYR B 1 122 ? 23.058  38.535 7.137  1.000 33.354  0 103 TYR B CD1   1 ? ? 
ATOM   2818 C CD2   . TYR B 1 122 ? 24.148  38.587 5.048  1.000 31.580  0 103 TYR B CD2   1 ? ? 
ATOM   2819 C CE1   . TYR B 1 122 ? 23.991  37.616 7.593  1.000 33.191  0 103 TYR B CE1   1 ? ? 
ATOM   2820 C CE2   . TYR B 1 122 ? 25.084  37.675 5.486  1.000 30.919  0 103 TYR B CE2   1 ? ? 
ATOM   2821 C CZ    . TYR B 1 122 ? 25.018  37.202 6.764  1.000 34.626  0 103 TYR B CZ    1 ? ? 
ATOM   2822 O OH    . TYR B 1 122 ? 25.996  36.332 7.110  1.000 36.343  0 103 TYR B OH    1 ? ? 
ATOM   2823 N N     . THR B 1 123 ? 21.652  42.957 3.734  1.000 31.339  0 104 THR B N     1 ? ? 
ATOM   2824 C CA    . THR B 1 123 ? 20.588  43.700 3.095  1.000 31.931  0 104 THR B CA    1 ? ? 
ATOM   2825 C C     . THR B 1 123 ? 20.767  43.578 1.587  1.000 32.368  0 104 THR B C     1 ? ? 
ATOM   2826 O O     . THR B 1 123 ? 21.850  43.250 1.119  1.000 34.531  0 104 THR B O     1 ? ? 
ATOM   2827 C CB    . THR B 1 123 ? 20.593  45.155 3.580  1.000 32.123  0 104 THR B CB    1 ? ? 
ATOM   2828 O OG1   . THR B 1 123 ? 19.320  45.746 3.300  1.000 31.175  0 104 THR B OG1   1 ? ? 
ATOM   2829 C CG2   . THR B 1 123 ? 21.695  45.983 2.949  1.000 31.879  0 104 THR B CG2   1 ? ? 
ATOM   2830 N N     . LYS B 1 124 ? 19.708  43.865 0.838  1.000 34.113  0 105 LYS B N     1 ? ? 
ATOM   2831 C CA    . LYS B 1 124 ? 19.689  43.629 -0.597 1.000 33.957  0 105 LYS B CA    1 ? ? 
ATOM   2832 C C     . LYS B 1 124 ? 20.510  44.697 -1.319 1.000 32.179  0 105 LYS B C     1 ? ? 
ATOM   2833 O O     . LYS B 1 124 ? 21.305  44.407 -2.208 1.000 29.787  0 105 LYS B O     1 ? ? 
ATOM   2834 C CB    . LYS B 1 124 ? 18.237  43.729 -1.069 1.000 35.722  0 105 LYS B CB    1 ? ? 
ATOM   2835 C CG    . LYS B 1 124 ? 17.732  42.619 -1.959 1.000 36.472  0 105 LYS B CG    1 ? ? 
ATOM   2836 C CD    . LYS B 1 124 ? 16.460  42.986 -2.638 1.000 38.968  0 105 LYS B CD    1 ? ? 
ATOM   2837 C CE    . LYS B 1 124 ? 16.658  43.427 -4.073 1.000 38.112  0 105 LYS B CE    1 ? ? 
ATOM   2838 N NZ    . LYS B 1 124 ? 17.138  42.326 -4.936 1.000 37.163  0 105 LYS B NZ    1 ? ? 
ATOM   2839 N N     . GLY B 1 125 ? 20.271  45.951 -0.963 1.000 30.730  0 106 GLY B N     1 ? ? 
ATOM   2840 C CA    . GLY B 1 125 ? 20.821  47.077 -1.696 1.000 35.305  0 106 GLY B CA    1 ? ? 
ATOM   2841 C C     . GLY B 1 125 ? 20.456  47.077 -3.177 1.000 39.599  0 106 GLY B C     1 ? ? 
ATOM   2842 O O     . GLY B 1 125 ? 19.606  46.307 -3.621 1.000 43.128  0 106 GLY B O     1 ? ? 
ATOM   2843 N N     . GLY B 1 126 ? 21.109  47.981 -3.909 1.000 39.268  0 107 GLY B N     1 ? ? 
ATOM   2844 C CA    . GLY B 1 126 ? 20.847  48.181 -5.319 1.000 38.176  0 107 GLY B CA    1 ? ? 
ATOM   2845 C C     . GLY B 1 126 ? 19.746  49.212 -5.538 1.000 39.685  0 107 GLY B C     1 ? ? 
ATOM   2846 O O     . GLY B 1 126 ? 19.347  49.947 -4.620 1.000 41.442  0 107 GLY B O     1 ? ? 
ATOM   2847 N N     . PRO B 1 127 ? 19.208  49.282 -6.774 1.000 38.720  0 108 PRO B N     1 ? ? 
ATOM   2848 C CA    . PRO B 1 127 ? 18.112  50.202 -7.069 1.000 38.702  0 108 PRO B CA    1 ? ? 
ATOM   2849 C C     . PRO B 1 127 ? 16.954  50.022 -6.092 1.000 36.969  0 108 PRO B C     1 ? ? 
ATOM   2850 O O     . PRO B 1 127 ? 16.471  48.912 -5.888 1.000 36.369  0 108 PRO B O     1 ? ? 
ATOM   2851 C CB    . PRO B 1 127 ? 17.694  49.815 -8.500 1.000 37.617  0 108 PRO B CB    1 ? ? 
ATOM   2852 C CG    . PRO B 1 127 ? 18.956  49.217 -9.101 1.000 37.017  0 108 PRO B CG    1 ? ? 
ATOM   2853 C CD    . PRO B 1 127 ? 19.635  48.503 -7.947 1.000 37.364  0 108 PRO B CD    1 ? ? 
ATOM   2854 N N     . GLY B 1 128 ? 16.553  51.135 -5.472 1.000 36.785  0 109 GLY B N     1 ? ? 
ATOM   2855 C CA    . GLY B 1 128 ? 15.363  51.177 -4.642 1.000 39.312  0 109 GLY B CA    1 ? ? 
ATOM   2856 C C     . GLY B 1 128 ? 15.635  50.824 -3.181 1.000 39.580  0 109 GLY B C     1 ? ? 
ATOM   2857 O O     . GLY B 1 128 ? 14.816  51.125 -2.322 1.000 37.530  0 109 GLY B O     1 ? ? 
ATOM   2858 N N     . HIS B 1 129 ? 16.785  50.207 -2.898 1.000 38.524  0 110 HIS B N     1 ? ? 
ATOM   2859 C CA    . HIS B 1 129 ? 17.004  49.686 -1.569 1.000 38.176  0 110 HIS B CA    1 ? ? 
ATOM   2860 C C     . HIS B 1 129 ? 18.173  50.389 -0.905 1.000 39.676  0 110 HIS B C     1 ? ? 
ATOM   2861 O O     . HIS B 1 129 ? 19.222  50.622 -1.519 1.000 38.303  0 110 HIS B O     1 ? ? 
ATOM   2862 C CB    . HIS B 1 129 ? 17.234  48.186 -1.608 1.000 38.142  0 110 HIS B CB    1 ? ? 
ATOM   2863 C CG    . HIS B 1 129 ? 16.091  47.407 -2.144 1.000 40.545  0 110 HIS B CG    1 ? ? 
ATOM   2864 N ND1   . HIS B 1 129 ? 15.068  46.985 -1.346 1.000 41.256  0 110 HIS B ND1   1 ? ? 
ATOM   2865 C CD2   . HIS B 1 129 ? 15.772  47.045 -3.402 1.000 42.667  0 110 HIS B CD2   1 ? ? 
ATOM   2866 C CE1   . HIS B 1 129 ? 14.175  46.362 -2.086 1.000 42.346  0 110 HIS B CE1   1 ? ? 
ATOM   2867 N NE2   . HIS B 1 129 ? 14.581  46.391 -3.354 1.000 43.432  0 110 HIS B NE2   1 ? ? 
ATOM   2868 N N     . GLU B 1 130 ? 18.017  50.588 0.406  1.000 41.023  0 111 GLU B N     1 ? ? 
ATOM   2869 C CA    . GLU B 1 130 ? 18.987  51.278 1.239  1.000 40.624  0 111 GLU B CA    1 ? ? 
ATOM   2870 C C     . GLU B 1 130 ? 20.304  50.512 1.271  1.000 37.002  0 111 GLU B C     1 ? ? 
ATOM   2871 O O     . GLU B 1 130 ? 20.300  49.293 1.437  1.000 38.952  0 111 GLU B O     1 ? ? 
ATOM   2872 C CB    . GLU B 1 130 ? 18.463  51.394 2.672  1.000 41.902  0 111 GLU B CB    1 ? ? 
ATOM   2873 C CG    . GLU B 1 130 ? 17.141  52.114 2.818  1.000 48.374  0 111 GLU B CG    1 ? ? 
ATOM   2874 C CD    . GLU B 1 130 ? 16.984  53.307 1.904  1.000 54.903  0 111 GLU B CD    1 ? ? 
ATOM   2875 O OE1   . GLU B 1 130 ? 16.367  53.134 0.815  1.000 58.463  0 111 GLU B OE1   1 ? ? 
ATOM   2876 O OE2   . GLU B 1 130 ? 17.486  54.392 2.284  1.000 55.910  0 111 GLU B OE2   1 ? ? 
ATOM   2877 N N     . GLU B 1 131 ? 21.421  51.252 1.201  1.000 34.606  0 112 GLU B N     1 ? ? 
ATOM   2878 C CA    . GLU B 1 131 ? 22.748  50.658 1.286  1.000 32.550  0 112 GLU B CA    1 ? ? 
ATOM   2879 C C     . GLU B 1 131 ? 23.301  50.834 2.690  1.000 27.978  0 112 GLU B C     1 ? ? 
ATOM   2880 O O     . GLU B 1 131 ? 23.039  51.844 3.329  1.000 27.060  0 112 GLU B O     1 ? ? 
ATOM   2881 C CB    . GLU B 1 131 ? 23.705  51.307 0.286  1.000 33.031  0 112 GLU B CB    1 ? ? 
ATOM   2882 C CG    . GLU B 1 131 ? 23.326  51.013 -1.159 1.000 33.579  0 112 GLU B CG    1 ? ? 
ATOM   2883 C CD    . GLU B 1 131 ? 23.659  49.603 -1.609 1.000 34.856  0 112 GLU B CD    1 ? ? 
ATOM   2884 O OE1   . GLU B 1 131 ? 24.293  48.869 -0.825 1.000 35.717  0 112 GLU B OE1   1 ? ? 
ATOM   2885 O OE2   . GLU B 1 131 ? 23.279  49.229 -2.740 1.000 33.664  0 112 GLU B OE2   1 ? ? 
ATOM   2886 N N     . PRO B 1 132 ? 24.072  49.864 3.220  1.000 27.422  0 113 PRO B N     1 ? ? 
ATOM   2887 C CA    . PRO B 1 132 ? 24.715  50.033 4.525  1.000 26.882  0 113 PRO B CA    1 ? ? 
ATOM   2888 C C     . PRO B 1 132 ? 25.558  51.301 4.568  1.000 26.563  0 113 PRO B C     1 ? ? 
ATOM   2889 O O     . PRO B 1 132 ? 26.209  51.674 3.591  1.000 27.612  0 113 PRO B O     1 ? ? 
ATOM   2890 C CB    . PRO B 1 132 ? 25.590  48.782 4.662  1.000 26.450  0 113 PRO B CB    1 ? ? 
ATOM   2891 C CG    . PRO B 1 132 ? 24.911  47.752 3.778  1.000 26.523  0 113 PRO B CG    1 ? ? 
ATOM   2892 C CD    . PRO B 1 132 ? 24.303  48.534 2.641  1.000 26.574  0 113 PRO B CD    1 ? ? 
ATOM   2893 N N     . VAL B 1 133 ? 25.496  51.972 5.716  1.000 25.971  0 114 VAL B N     1 ? ? 
ATOM   2894 C CA    . VAL B 1 133 ? 26.227  53.201 5.937  1.000 25.561  0 114 VAL B CA    1 ? ? 
ATOM   2895 C C     . VAL B 1 133 ? 27.382  52.888 6.878  1.000 27.346  0 114 VAL B C     1 ? ? 
ATOM   2896 O O     . VAL B 1 133 ? 27.163  52.393 7.982  1.000 29.310  0 114 VAL B O     1 ? ? 
ATOM   2897 C CB    . VAL B 1 133 ? 25.320  54.314 6.487  1.000 24.284  0 114 VAL B CB    1 ? ? 
ATOM   2898 C CG1   . VAL B 1 133 ? 26.145  55.498 6.976  1.000 23.083  0 114 VAL B CG1   1 ? ? 
ATOM   2899 C CG2   . VAL B 1 133 ? 24.265  54.740 5.476  1.000 23.200  0 114 VAL B CG2   1 ? ? 
ATOM   2900 N N     . PRO B 1 134 ? 28.652  53.073 6.440  1.000 28.632  0 115 PRO B N     1 ? ? 
ATOM   2901 C CA    . PRO B 1 134 ? 29.798  52.841 7.327  1.000 26.718  0 115 PRO B CA    1 ? ? 
ATOM   2902 C C     . PRO B 1 134 ? 29.892  53.846 8.473  1.000 25.384  0 115 PRO B C     1 ? ? 
ATOM   2903 O O     . PRO B 1 134 ? 29.852  55.052 8.240  1.000 25.696  0 115 PRO B O     1 ? ? 
ATOM   2904 C CB    . PRO B 1 134 ? 30.989  52.929 6.361  1.000 26.461  0 115 PRO B CB    1 ? ? 
ATOM   2905 C CG    . PRO B 1 134 ? 30.488  53.791 5.221  1.000 25.694  0 115 PRO B CG    1 ? ? 
ATOM   2906 C CD    . PRO B 1 134 ? 29.040  53.381 5.050  1.000 25.710  0 115 PRO B CD    1 ? ? 
ATOM   2907 N N     . MET B 1 135 ? 30.055  53.334 9.705  1.000 24.788  0 116 MET B N     1 ? ? 
ATOM   2908 C CA    . MET B 1 135 ? 30.108  54.187 10.887 1.000 23.553  0 116 MET B CA    1 ? ? 
ATOM   2909 C C     . MET B 1 135 ? 31.221  53.736 11.831 1.000 22.979  0 116 MET B C     1 ? ? 
ATOM   2910 O O     . MET B 1 135 ? 31.739  52.637 11.701 1.000 23.804  0 116 MET B O     1 ? ? 
ATOM   2911 C CB    . MET B 1 135 ? 28.764  54.205 11.630 1.000 22.926  0 116 MET B CB    1 ? ? 
ATOM   2912 C CG    . MET B 1 135 ? 27.636  54.821 10.826 1.000 21.538  0 116 MET B CG    1 ? ? 
ATOM   2913 S SD    . MET B 1 135 ? 27.818  56.606 10.590 1.000 22.403  0 116 MET B SD    1 ? ? 
ATOM   2914 C CE    . MET B 1 135 ? 27.441  57.257 12.214 1.000 21.911  0 116 MET B CE    1 ? ? 
ATOM   2915 N N     . SER B 1 136 ? 31.571  54.613 12.775 1.000 23.465  0 117 SER B N     1 ? ? 
ATOM   2916 C CA    . SER B 1 136 ? 32.578  54.341 13.785 1.000 24.050  0 117 SER B CA    1 ? ? 
ATOM   2917 C C     . SER B 1 136 ? 31.992  54.556 15.176 1.000 23.422  0 117 SER B C     1 ? ? 
ATOM   2918 O O     . SER B 1 136 ? 32.700  54.987 16.090 1.000 23.827  0 117 SER B O     1 ? ? 
ATOM   2919 C CB    . SER B 1 136 ? 33.768  55.254 13.591 1.000 25.704  0 117 SER B CB    1 ? ? 
ATOM   2920 O OG    . SER B 1 136 ? 34.499  54.871 12.443 1.000 29.618  0 117 SER B OG    1 ? ? 
ATOM   2921 N N     . THR B 1 137 ? 30.695  54.292 15.318 1.000 21.799  0 118 THR B N     1 ? ? 
ATOM   2922 C CA    . THR B 1 137 ? 30.042  54.325 16.613 1.000 21.981  0 118 THR B CA    1 ? ? 
ATOM   2923 C C     . THR B 1 137 ? 30.591  53.197 17.482 1.000 23.314  0 118 THR B C     1 ? ? 
ATOM   2924 O O     . THR B 1 137 ? 31.270  52.301 16.986 1.000 23.995  0 118 THR B O     1 ? ? 
ATOM   2925 C CB    . THR B 1 137 ? 28.524  54.279 16.419 1.000 20.846  0 118 THR B CB    1 ? ? 
ATOM   2926 O OG1   . THR B 1 137 ? 28.228  53.223 15.505 1.000 18.752  0 118 THR B OG1   1 ? ? 
ATOM   2927 C CG2   . THR B 1 137 ? 28.009  55.590 15.873 1.000 20.468  0 118 THR B CG2   1 ? ? 
ATOM   2928 N N     . TYR B 1 138 ? 30.298  53.254 18.786 1.000 22.763  0 119 TYR B N     1 ? ? 
ATOM   2929 C CA    . TYR B 1 138 ? 30.917  52.339 19.728 1.000 22.881  0 119 TYR B CA    1 ? ? 
ATOM   2930 C C     . TYR B 1 138 ? 30.698  50.879 19.344 1.000 21.943  0 119 TYR B C     1 ? ? 
ATOM   2931 O O     . TYR B 1 138 ? 29.558  50.432 19.221 1.000 22.401  0 119 TYR B O     1 ? ? 
ATOM   2932 C CB    . TYR B 1 138 ? 30.441  52.603 21.152 1.000 24.398  0 119 TYR B CB    1 ? ? 
ATOM   2933 C CG    . TYR B 1 138 ? 31.123  51.718 22.157 1.000 27.204  0 119 TYR B CG    1 ? ? 
ATOM   2934 C CD1   . TYR B 1 138 ? 32.502  51.742 22.308 1.000 29.241  0 119 TYR B CD1   1 ? ? 
ATOM   2935 C CD2   . TYR B 1 138 ? 30.394  50.826 22.919 1.000 27.418  0 119 TYR B CD2   1 ? ? 
ATOM   2936 C CE1   . TYR B 1 138 ? 33.144  50.928 23.225 1.000 30.587  0 119 TYR B CE1   1 ? ? 
ATOM   2937 C CE2   . TYR B 1 138 ? 31.019  50.007 23.841 1.000 28.826  0 119 TYR B CE2   1 ? ? 
ATOM   2938 C CZ    . TYR B 1 138 ? 32.393  50.064 24.003 1.000 30.361  0 119 TYR B CZ    1 ? ? 
ATOM   2939 O OH    . TYR B 1 138 ? 33.003  49.278 24.938 1.000 31.101  0 119 TYR B OH    1 ? ? 
ATOM   2940 N N     . GLY B 1 139 ? 31.812  50.151 19.177 1.000 20.396  0 120 GLY B N     1 ? ? 
ATOM   2941 C CA    . GLY B 1 139 ? 31.746  48.741 18.851 1.000 20.586  0 120 GLY B CA    1 ? ? 
ATOM   2942 C C     . GLY B 1 139 ? 31.639  48.461 17.354 1.000 21.148  0 120 GLY B C     1 ? ? 
ATOM   2943 O O     . GLY B 1 139 ? 31.339  47.335 16.973 1.000 22.028  0 120 GLY B O     1 ? ? 
ATOM   2944 N N     . TRP B 1 140 ? 31.905  49.464 16.511 1.000 19.910  0 121 TRP B N     1 ? ? 
ATOM   2945 C CA    . TRP B 1 140 ? 31.787  49.300 15.068 1.000 20.701  0 121 TRP B CA    1 ? ? 
ATOM   2946 C C     . TRP B 1 140 ? 32.643  48.145 14.560 1.000 20.207  0 121 TRP B C     1 ? ? 
ATOM   2947 O O     . TRP B 1 140 ? 32.295  47.505 13.580 1.000 20.100  0 121 TRP B O     1 ? ? 
ATOM   2948 C CB    . TRP B 1 140 ? 32.151  50.607 14.360 1.000 21.740  0 121 TRP B CB    1 ? ? 
ATOM   2949 C CG    . TRP B 1 140 ? 33.579  50.995 14.584 1.000 21.973  0 121 TRP B CG    1 ? ? 
ATOM   2950 C CD1   . TRP B 1 140 ? 34.105  51.724 15.616 1.000 21.571  0 121 TRP B CD1   1 ? ? 
ATOM   2951 C CD2   . TRP B 1 140 ? 34.690  50.608 13.766 1.000 22.310  0 121 TRP B CD2   1 ? ? 
ATOM   2952 N NE1   . TRP B 1 140 ? 35.467  51.831 15.490 1.000 20.636  0 121 TRP B NE1   1 ? ? 
ATOM   2953 C CE2   . TRP B 1 140 ? 35.848  51.162 14.362 1.000 21.749  0 121 TRP B CE2   1 ? ? 
ATOM   2954 C CE3   . TRP B 1 140 ? 34.807  49.867 12.582 1.000 22.247  0 121 TRP B CE3   1 ? ? 
ATOM   2955 C CZ2   . TRP B 1 140 ? 37.110  50.986 13.805 1.000 22.725  0 121 TRP B CZ2   1 ? ? 
ATOM   2956 C CZ3   . TRP B 1 140 ? 36.061  49.683 12.041 1.000 22.152  0 121 TRP B CZ3   1 ? ? 
ATOM   2957 C CH2   . TRP B 1 140 ? 37.189  50.243 12.643 1.000 22.378  0 121 TRP B CH2   1 ? ? 
ATOM   2958 N N     . ASN B 1 141 ? 33.747  47.863 15.251 1.000 21.582  0 122 ASN B N     1 ? ? 
ATOM   2959 C CA    . ASN B 1 141 ? 34.727  46.909 14.761 1.000 22.490  0 122 ASN B CA    1 ? ? 
ATOM   2960 C C     . ASN B 1 141 ? 34.219  45.473 14.820 1.000 23.320  0 122 ASN B C     1 ? ? 
ATOM   2961 O O     . ASN B 1 141 ? 34.889  44.593 14.302 1.000 24.159  0 122 ASN B O     1 ? ? 
ATOM   2962 C CB    . ASN B 1 141 ? 36.010  46.973 15.583 1.000 23.272  0 122 ASN B CB    1 ? ? 
ATOM   2963 C CG    . ASN B 1 141 ? 35.747  46.819 17.065 1.000 23.360  0 122 ASN B CG    1 ? ? 
ATOM   2964 O OD1   . ASN B 1 141 ? 35.095  47.661 17.686 1.000 22.560  0 122 ASN B OD1   1 ? ? 
ATOM   2965 N ND2   . ASN B 1 141 ? 36.229  45.721 17.616 1.000 23.583  0 122 ASN B ND2   1 ? ? 
ATOM   2966 N N     . ILE B 1 142 ? 33.077  45.217 15.472 1.000 24.922  0 123 ILE B N     1 ? ? 
ATOM   2967 C CA    . ILE B 1 142 ? 32.517  43.865 15.512 1.000 24.418  0 123 ILE B CA    1 ? ? 
ATOM   2968 C C     . ILE B 1 142 ? 31.336  43.722 14.557 1.000 25.042  0 123 ILE B C     1 ? ? 
ATOM   2969 O O     . ILE B 1 142 ? 30.681  42.681 14.595 1.000 28.140  0 123 ILE B O     1 ? ? 
ATOM   2970 C CB    . ILE B 1 142 ? 32.133  43.432 16.946 1.000 23.954  0 123 ILE B CB    1 ? ? 
ATOM   2971 C CG1   . ILE B 1 142 ? 30.866  44.136 17.453 1.000 22.849  0 123 ILE B CG1   1 ? ? 
ATOM   2972 C CG2   . ILE B 1 142 ? 33.329  43.639 17.868 1.000 23.093  0 123 ILE B CG2   1 ? ? 
ATOM   2973 C CD1   . ILE B 1 142 ? 30.230  43.459 18.636 1.000 24.053  0 123 ILE B CD1   1 ? ? 
ATOM   2974 N N     . VAL B 1 143 ? 31.098  44.739 13.714 1.000 24.580  0 124 VAL B N     1 ? ? 
ATOM   2975 C CA    . VAL B 1 143 ? 29.996  44.760 12.761 1.000 25.485  0 124 VAL B CA    1 ? ? 
ATOM   2976 C C     . VAL B 1 143 ? 30.530  44.448 11.368 1.000 26.812  0 124 VAL B C     1 ? ? 
ATOM   2977 O O     . VAL B 1 143 ? 31.545  45.010 10.975 1.000 28.245  0 124 VAL B O     1 ? ? 
ATOM   2978 C CB    . VAL B 1 143 ? 29.308  46.138 12.737 1.000 25.352  0 124 VAL B CB    1 ? ? 
ATOM   2979 C CG1   . VAL B 1 143 ? 28.078  46.088 11.853 1.000 24.633  0 124 VAL B CG1   1 ? ? 
ATOM   2980 C CG2   . VAL B 1 143 ? 28.947  46.626 14.129 1.000 24.593  0 124 VAL B CG2   1 ? ? 
ATOM   2981 N N     . LYS B 1 144 ? 29.831  43.579 10.626 1.000 28.270  0 125 LYS B N     1 ? ? 
ATOM   2982 C CA    . LYS B 1 144 ? 30.046  43.443 9.193  1.000 29.699  0 125 LYS B CA    1 ? ? 
ATOM   2983 C C     . LYS B 1 144 ? 28.697  43.495 8.482  1.000 30.728  0 125 LYS B C     1 ? ? 
ATOM   2984 O O     . LYS B 1 144 ? 27.876  42.604 8.652  1.000 31.372  0 125 LYS B O     1 ? ? 
ATOM   2985 C CB    . LYS B 1 144 ? 30.841  42.175 8.868  1.000 31.977  0 125 LYS B CB    1 ? ? 
ATOM   2986 C CG    . LYS B 1 144 ? 31.038  41.858 7.398  1.000 35.897  0 125 LYS B CG    1 ? ? 
ATOM   2987 C CD    . LYS B 1 144 ? 32.421  42.070 6.777  1.000 40.267  0 125 LYS B CD    1 ? ? 
ATOM   2988 C CE    . LYS B 1 144 ? 32.421  41.970 5.268  1.000 37.822  0 125 LYS B CE    1 ? ? 
ATOM   2989 N NZ    . LYS B 1 144 ? 32.485  40.556 4.865  1.000 36.403  0 125 LYS B NZ    1 ? ? 
ATOM   2990 N N     . LEU B 1 145 ? 28.478  44.573 7.718  1.000 31.585  0 126 LEU B N     1 ? ? 
ATOM   2991 C CA    . LEU B 1 145 ? 27.257  44.805 6.964  1.000 32.675  0 126 LEU B CA    1 ? ? 
ATOM   2992 C C     . LEU B 1 145 ? 27.520  44.509 5.496  1.000 33.882  0 126 LEU B C     1 ? ? 
ATOM   2993 O O     . LEU B 1 145 ? 28.442  45.076 4.916  1.000 37.185  0 126 LEU B O     1 ? ? 
ATOM   2994 C CB    . LEU B 1 145 ? 26.824  46.271 7.102  1.000 32.138  0 126 LEU B CB    1 ? ? 
ATOM   2995 C CG    . LEU B 1 145 ? 26.476  46.713 8.521  1.000 33.435  0 126 LEU B CG    1 ? ? 
ATOM   2996 C CD1   . LEU B 1 145 ? 27.726  46.857 9.353  1.000 35.638  0 126 LEU B CD1   1 ? ? 
ATOM   2997 C CD2   . LEU B 1 145 ? 25.701  47.996 8.575  1.000 30.453  0 126 LEU B CD2   1 ? ? 
ATOM   2998 N N     . MET B 1 146 ? 26.690  43.634 4.914  1.000 34.980  0 127 MET B N     1 ? ? 
ATOM   2999 C CA    . MET B 1 146 ? 26.927  43.094 3.585  1.000 34.329  0 127 MET B CA    1 ? ? 
ATOM   3000 C C     . MET B 1 146 ? 25.731  43.393 2.700  1.000 32.700  0 127 MET B C     1 ? ? 
ATOM   3001 O O     . MET B 1 146 ? 24.606  42.998 2.995  1.000 34.307  0 127 MET B O     1 ? ? 
ATOM   3002 C CB    . MET B 1 146 ? 27.171  41.581 3.637  1.000 36.436  0 127 MET B CB    1 ? ? 
ATOM   3003 C CG    . MET B 1 146 ? 28.469  41.225 4.326  1.000 38.530  0 127 MET B CG    1 ? ? 
ATOM   3004 S SD    . MET B 1 146 ? 28.608  39.494 4.768  1.000 47.325  0 127 MET B SD    1 ? ? 
ATOM   3005 C CE    . MET B 1 146 ? 28.256  39.634 6.513  1.000 40.187  0 127 MET B CE    1 ? ? 
ATOM   3006 N N     . SER B 1 147 ? 25.996  44.130 1.620  1.000 32.448  0 128 SER B N     1 ? ? 
ATOM   3007 C CA    . SER B 1 147 ? 24.960  44.459 0.658  1.000 31.144  0 128 SER B CA    1 ? ? 
ATOM   3008 C C     . SER B 1 147 ? 24.942  43.362 -0.399 1.000 31.285  0 128 SER B C     1 ? ? 
ATOM   3009 O O     . SER B 1 147 ? 25.769  42.453 -0.344 1.000 28.426  0 128 SER B O     1 ? ? 
ATOM   3010 C CB    . SER B 1 147 ? 25.183  45.824 0.096  1.000 30.449  0 128 SER B CB    1 ? ? 
ATOM   3011 O OG    . SER B 1 147 ? 23.962  46.365 -0.375 1.000 27.091  0 128 SER B OG    1 ? ? 
ATOM   3012 N N     . GLY B 1 148 ? 23.971  43.431 -1.320 1.000 33.931  0 129 GLY B N     1 ? ? 
ATOM   3013 C CA    . GLY B 1 148 ? 23.772  42.431 -2.360 1.000 34.619  0 129 GLY B CA    1 ? ? 
ATOM   3014 C C     . GLY B 1 148 ? 23.391  41.063 -1.806 1.000 36.222  0 129 GLY B C     1 ? ? 
ATOM   3015 O O     . GLY B 1 148 ? 23.686  40.041 -2.421 1.000 36.485  0 129 GLY B O     1 ? ? 
ATOM   3016 N N     . LYS B 1 149 ? 22.758  41.041 -0.630 1.000 39.718  0 130 LYS B N     1 ? ? 
ATOM   3017 C CA    . LYS B 1 149 ? 22.348  39.783 -0.023 1.000 43.350  0 130 LYS B CA    1 ? ? 
ATOM   3018 C C     . LYS B 1 149 ? 20.829  39.747 0.050  1.000 43.151  0 130 LYS B C     1 ? ? 
ATOM   3019 O O     . LYS B 1 149 ? 20.210  40.560 0.720  1.000 42.097  0 130 LYS B O     1 ? ? 
ATOM   3020 C CB    . LYS B 1 149 ? 22.946  39.595 1.373  1.000 43.011  0 130 LYS B CB    1 ? ? 
ATOM   3021 C CG    . LYS B 1 149 ? 24.461  39.532 1.393  1.000 47.954  0 130 LYS B CG    1 ? ? 
ATOM   3022 C CD    . LYS B 1 149 ? 25.018  38.159 1.138  1.000 50.943  0 130 LYS B CD    1 ? ? 
ATOM   3023 C CE    . LYS B 1 149 ? 26.516  38.149 1.348  1.000 51.115  0 130 LYS B CE    1 ? ? 
ATOM   3024 N NZ    . LYS B 1 149 ? 27.123  36.851 0.971  1.000 50.516  0 130 LYS B NZ    1 ? ? 
ATOM   3025 N N     . ASP B 1 150 ? 20.244  38.820 -0.702 1.000 46.393  0 131 ASP B N     1 ? ? 
ATOM   3026 C CA    . ASP B 1 150 ? 18.830  38.522 -0.601 1.000 48.294  0 131 ASP B CA    1 ? ? 
ATOM   3027 C C     . ASP B 1 150 ? 18.658  37.464 0.485  1.000 48.562  0 131 ASP B C     1 ? ? 
ATOM   3028 O O     . ASP B 1 150 ? 19.184  36.356 0.381  1.000 48.942  0 131 ASP B O     1 ? ? 
ATOM   3029 C CB    . ASP B 1 150 ? 18.246  38.141 -1.971 1.000 51.009  0 131 ASP B CB    1 ? ? 
ATOM   3030 C CG    . ASP B 1 150 ? 16.761  37.885 -1.883 1.000 52.183  0 131 ASP B CG    1 ? ? 
ATOM   3031 O OD1   . ASP B 1 150 ? 16.445  37.024 -1.094 1.000 51.980  0 131 ASP B OD1   1 ? ? 
ATOM   3032 O OD2   . ASP B 1 150 ? 15.949  38.476 -2.623 1.000 53.756  0 131 ASP B OD2   1 ? ? 
ATOM   3033 N N     . VAL B 1 151 ? 17.917  37.807 1.535  1.000 46.645  0 132 VAL B N     1 ? ? 
ATOM   3034 C CA    . VAL B 1 151 ? 17.855  36.936 2.691  1.000 46.989  0 132 VAL B CA    1 ? ? 
ATOM   3035 C C     . VAL B 1 151 ? 17.122  35.643 2.338  1.000 48.649  0 132 VAL B C     1 ? ? 
ATOM   3036 O O     . VAL B 1 151 ? 17.282  34.622 3.011  1.000 47.594  0 132 VAL B O     1 ? ? 
ATOM   3037 C CB    . VAL B 1 151 ? 17.192  37.663 3.879  1.000 47.346  0 132 VAL B CB    1 ? ? 
ATOM   3038 C CG1   . VAL B 1 151 ? 18.187  38.614 4.531  1.000 46.378  0 132 VAL B CG1   1 ? ? 
ATOM   3039 C CG2   . VAL B 1 151 ? 15.915  38.401 3.458  1.000 49.981  0 132 VAL B CG2   1 ? ? 
ATOM   3040 N N     . PHE B 1 152 ? 16.296  35.688 1.286  1.000 50.860  0 133 PHE B N     1 ? ? 
ATOM   3041 C CA    . PHE B 1 152 ? 15.491  34.530 0.940  1.000 55.200  0 133 PHE B CA    1 ? ? 
ATOM   3042 C C     . PHE B 1 152 ? 16.384  33.439 0.345  1.000 59.396  0 133 PHE B C     1 ? ? 
ATOM   3043 O O     . PHE B 1 152 ? 16.007  32.272 0.374  1.000 59.942  0 133 PHE B O     1 ? ? 
ATOM   3044 C CB    . PHE B 1 152 ? 14.312  34.899 0.033  1.000 52.390  0 133 PHE B CB    1 ? ? 
ATOM   3045 C CG    . PHE B 1 152 ? 13.301  35.811 0.665  1.000 49.501  0 133 PHE B CG    1 ? ? 
ATOM   3046 C CD1   . PHE B 1 152 ? 12.562  35.360 1.739  1.000 47.956  0 133 PHE B CD1   1 ? ? 
ATOM   3047 C CD2   . PHE B 1 152 ? 13.100  37.113 0.225  1.000 47.309  0 133 PHE B CD2   1 ? ? 
ATOM   3048 C CE1   . PHE B 1 152 ? 11.652  36.192 2.367  1.000 49.115  0 133 PHE B CE1   1 ? ? 
ATOM   3049 C CE2   . PHE B 1 152 ? 12.170  37.937 0.854  1.000 48.183  0 133 PHE B CE2   1 ? ? 
ATOM   3050 C CZ    . PHE B 1 152 ? 11.447  37.473 1.924  1.000 48.401  0 133 PHE B CZ    1 ? ? 
ATOM   3051 N N     . TYR B 1 153 ? 17.600  33.805 -0.089 1.000 61.090  0 134 TYR B N     1 ? ? 
ATOM   3052 C CA    . TYR B 1 153 ? 18.526  32.819 -0.638 1.000 63.613  0 134 TYR B CA    1 ? ? 
ATOM   3053 C C     . TYR B 1 153 ? 19.739  32.619 0.272  1.000 62.793  0 134 TYR B C     1 ? ? 
ATOM   3054 O O     . TYR B 1 153 ? 20.724  31.984 -0.125 1.000 63.723  0 134 TYR B O     1 ? ? 
ATOM   3055 C CB    . TYR B 1 153 ? 19.008  33.220 -2.034 1.000 62.188  0 134 TYR B CB    1 ? ? 
ATOM   3056 C CG    . TYR B 1 153 ? 17.913  33.581 -2.996 1.000 61.260  0 134 TYR B CG    1 ? ? 
ATOM   3057 C CD1   . TYR B 1 153 ? 17.120  32.606 -3.567 1.000 62.030  0 134 TYR B CD1   1 ? ? 
ATOM   3058 C CD2   . TYR B 1 153 ? 17.675  34.901 -3.325 1.000 61.941  0 134 TYR B CD2   1 ? ? 
ATOM   3059 C CE1   . TYR B 1 153 ? 16.108  32.954 -4.449 1.000 67.790  0 134 TYR B CE1   1 ? ? 
ATOM   3060 C CE2   . TYR B 1 153 ? 16.627  35.296 -4.129 1.000 65.183  0 134 TYR B CE2   1 ? ? 
ATOM   3061 C CZ    . TYR B 1 153 ? 15.871  34.295 -4.739 1.000 71.596  0 134 TYR B CZ    1 ? ? 
ATOM   3062 O OH    . TYR B 1 153 ? 14.867  34.627 -5.603 1.000 78.984  0 134 TYR B OH    1 ? ? 
ATOM   3063 N N     . LEU B 1 154 ? 19.654  33.127 1.506  1.000 57.249  0 135 LEU B N     1 ? ? 
ATOM   3064 C CA    . LEU B 1 154 ? 20.742  32.999 2.459  1.000 56.589  0 135 LEU B CA    1 ? ? 
ATOM   3065 C C     . LEU B 1 154 ? 20.580  31.728 3.282  1.000 56.064  0 135 LEU B C     1 ? ? 
ATOM   3066 O O     . LEU B 1 154 ? 19.599  31.554 3.997  1.000 58.501  0 135 LEU B O     1 ? ? 
ATOM   3067 C CB    . LEU B 1 154 ? 20.716  34.190 3.409  1.000 61.489  0 135 LEU B CB    1 ? ? 
ATOM   3068 C CG    . LEU B 1 154 ? 21.612  35.358 3.066  1.000 66.216  0 135 LEU B CG    1 ? ? 
ATOM   3069 C CD1   . LEU B 1 154 ? 21.406  36.379 4.132  1.000 69.246  0 135 LEU B CD1   1 ? ? 
ATOM   3070 C CD2   . LEU B 1 154 ? 23.073  34.967 3.010  1.000 65.603  0 135 LEU B CD2   1 ? ? 
ATOM   3071 N N     . PRO B 1 155 ? 21.565  30.817 3.240  1.000 53.281  0 136 PRO B N     1 ? ? 
ATOM   3072 C CA    . PRO B 1 155 ? 21.527  29.642 4.104  1.000 49.829  0 136 PRO B CA    1 ? ? 
ATOM   3073 C C     . PRO B 1 155 ? 21.488  30.091 5.557  1.000 49.567  0 136 PRO B C     1 ? ? 
ATOM   3074 O O     . PRO B 1 155 ? 22.218  31.003 5.935  1.000 47.735  0 136 PRO B O     1 ? ? 
ATOM   3075 C CB    . PRO B 1 155 ? 22.830  28.915 3.788  1.000 48.567  0 136 PRO B CB    1 ? ? 
ATOM   3076 C CG    . PRO B 1 155 ? 23.669  29.955 3.081  1.000 50.662  0 136 PRO B CG    1 ? ? 
ATOM   3077 C CD    . PRO B 1 155 ? 22.710  30.853 2.322  1.000 50.961  0 136 PRO B CD    1 ? ? 
ATOM   3078 N N     . PRO B 1 156 ? 20.583  29.510 6.378  1.000 47.989  0 137 PRO B N     1 ? ? 
ATOM   3079 C CA    . PRO B 1 156 ? 20.554  29.745 7.821  1.000 46.901  0 137 PRO B CA    1 ? ? 
ATOM   3080 C C     . PRO B 1 156 ? 21.823  29.427 8.614  1.000 47.140  0 137 PRO B C     1 ? ? 
ATOM   3081 O O     . PRO B 1 156 ? 22.286  28.297 8.707  1.000 48.159  0 137 PRO B O     1 ? ? 
ATOM   3082 C CB    . PRO B 1 156 ? 19.313  28.985 8.331  1.000 46.126  0 137 PRO B CB    1 ? ? 
ATOM   3083 C CG    . PRO B 1 156 ? 18.487  28.830 7.083  1.000 44.871  0 137 PRO B CG    1 ? ? 
ATOM   3084 C CD    . PRO B 1 156 ? 19.460  28.677 5.938  1.000 45.822  0 137 PRO B CD    1 ? ? 
ATOM   3085 N N     . GLU B 1 157 ? 22.307  30.422 9.355  1.000 46.452  0 138 GLU B N     1 ? ? 
ATOM   3086 C CA    . GLU B 1 157 ? 23.554  30.312 10.098 1.000 45.148  0 138 GLU B CA    1 ? ? 
ATOM   3087 C C     . GLU B 1 157 ? 23.257  30.192 11.588 1.000 43.883  0 138 GLU B C     1 ? ? 
ATOM   3088 O O     . GLU B 1 157 ? 22.205  30.621 12.048 1.000 43.546  0 138 GLU B O     1 ? ? 
ATOM   3089 C CB    . GLU B 1 157 ? 24.456  31.535 9.891  1.000 46.375  0 138 GLU B CB    1 ? ? 
ATOM   3090 C CG    . GLU B 1 157 ? 24.625  31.936 8.436  1.000 48.262  0 138 GLU B CG    1 ? ? 
ATOM   3091 C CD    . GLU B 1 157 ? 25.297  33.287 8.206  1.000 47.633  0 138 GLU B CD    1 ? ? 
ATOM   3092 O OE1   . GLU B 1 157 ? 25.862  33.876 9.126  1.000 48.949  0 138 GLU B OE1   1 ? ? 
ATOM   3093 O OE2   . GLU B 1 157 ? 25.251  33.765 7.091  1.000 47.682  0 138 GLU B OE2   1 ? ? 
ATOM   3094 N N     . LYS B 1 158 ? 24.220  29.661 12.349 1.000 43.783  0 139 LYS B N     1 ? ? 
ATOM   3095 C CA    . LYS B 1 158 ? 23.983  29.451 13.767 1.000 42.252  0 139 LYS B CA    1 ? ? 
ATOM   3096 C C     . LYS B 1 158 ? 24.263  30.746 14.503 1.000 41.772  0 139 LYS B C     1 ? ? 
ATOM   3097 O O     . LYS B 1 158 ? 25.411  31.141 14.609 1.000 43.233  0 139 LYS B O     1 ? ? 
ATOM   3098 C CB    . LYS B 1 158 ? 24.796  28.271 14.305 1.000 43.642  0 139 LYS B CB    1 ? ? 
ATOM   3099 C CG    . LYS B 1 158 ? 24.310  26.923 13.794 1.000 48.344  0 139 LYS B CG    1 ? ? 
ATOM   3100 C CD    . LYS B 1 158 ? 25.394  26.022 13.260 1.000 48.964  0 139 LYS B CD    1 ? ? 
ATOM   3101 C CE    . LYS B 1 158 ? 25.831  25.023 14.305 1.000 54.202  0 139 LYS B CE    1 ? ? 
ATOM   3102 N NZ    . LYS B 1 158 ? 27.049  24.275 13.902 1.000 55.226  0 139 LYS B NZ    1 ? ? 
ATOM   3103 N N     . CYS B 1 159 ? 23.222  31.329 15.097 1.000 40.189  0 140 CYS B N     1 ? ? 
ATOM   3104 C CA    . CYS B 1 159 ? 23.350  32.596 15.788 1.000 36.892  0 140 CYS B CA    1 ? ? 
ATOM   3105 C C     . CYS B 1 159 ? 22.681  32.515 17.155 1.000 35.569  0 140 CYS B C     1 ? ? 
ATOM   3106 O O     . CYS B 1 159 ? 21.973  31.559 17.443 1.000 33.487  0 140 CYS B O     1 ? ? 
ATOM   3107 C CB    . CYS B 1 159 ? 22.738  33.706 14.946 1.000 40.070  0 140 CYS B CB    1 ? ? 
ATOM   3108 S SG    . CYS B 1 159 ? 20.982  33.458 14.610 1.000 40.054  0 140 CYS B SG    1 ? ? 
ATOM   3109 N N     . ASP B 1 160 ? 22.929  33.527 17.994 1.000 34.308  0 141 ASP B N     1 ? ? 
ATOM   3110 C CA    . ASP B 1 160 ? 22.391  33.601 19.345 1.000 31.695  0 141 ASP B CA    1 ? ? 
ATOM   3111 C C     . ASP B 1 160 ? 21.241  34.605 19.387 1.000 30.862  0 141 ASP B C     1 ? ? 
ATOM   3112 O O     . ASP B 1 160 ? 20.384  34.501 20.265 1.000 32.251  0 141 ASP B O     1 ? ? 
ATOM   3113 C CB    . ASP B 1 160 ? 23.491  34.011 20.337 1.000 33.197  0 141 ASP B CB    1 ? ? 
ATOM   3114 C CG    . ASP B 1 160 ? 24.739  33.147 20.243 1.000 35.934  0 141 ASP B CG    1 ? ? 
ATOM   3115 O OD1   . ASP B 1 160 ? 24.667  31.977 20.656 1.000 40.779  0 141 ASP B OD1   1 ? ? 
ATOM   3116 O OD2   . ASP B 1 160 ? 25.765  33.637 19.738 1.000 36.654  0 141 ASP B OD2   1 ? ? 
ATOM   3117 N N     . THR B 1 161 ? 21.214  35.538 18.417 1.000 28.423  0 142 THR B N     1 ? ? 
ATOM   3118 C CA    . THR B 1 161 ? 20.163  36.531 18.271 1.000 25.974  0 142 THR B CA    1 ? ? 
ATOM   3119 C C     . THR B 1 161 ? 19.850  36.717 16.790 1.000 24.614  0 142 THR B C     1 ? ? 
ATOM   3120 O O     . THR B 1 161 ? 20.751  37.033 16.022 1.000 22.730  0 142 THR B O     1 ? ? 
ATOM   3121 C CB    . THR B 1 161 ? 20.594  37.895 18.827 1.000 25.643  0 142 THR B CB    1 ? ? 
ATOM   3122 O OG1   . THR B 1 161 ? 21.309  37.697 20.048 1.000 26.987  0 142 THR B OG1   1 ? ? 
ATOM   3123 C CG2   . THR B 1 161 ? 19.420  38.827 19.026 1.000 24.679  0 142 THR B CG2   1 ? ? 
ATOM   3124 N N     . LEU B 1 162 ? 18.579  36.540 16.406 1.000 24.417  0 143 LEU B N     1 ? ? 
ATOM   3125 C CA    . LEU B 1 162 ? 18.113  36.719 15.035 1.000 24.127  0 143 LEU B CA    1 ? ? 
ATOM   3126 C C     . LEU B 1 162 ? 17.226  37.960 14.962 1.000 23.862  0 143 LEU B C     1 ? ? 
ATOM   3127 O O     . LEU B 1 162 ? 16.130  37.969 15.521 1.000 24.001  0 143 LEU B O     1 ? ? 
ATOM   3128 C CB    . LEU B 1 162 ? 17.325  35.468 14.612 1.000 25.434  0 143 LEU B CB    1 ? ? 
ATOM   3129 C CG    . LEU B 1 162 ? 16.955  35.344 13.134 1.000 25.944  0 143 LEU B CG    1 ? ? 
ATOM   3130 C CD1   . LEU B 1 162 ? 15.780  36.230 12.753 1.000 24.303  0 143 LEU B CD1   1 ? ? 
ATOM   3131 C CD2   . LEU B 1 162 ? 18.153  35.641 12.244 1.000 26.659  0 143 LEU B CD2   1 ? ? 
ATOM   3132 N N     . LEU B 1 163 ? 17.702  39.004 14.281 1.000 22.939  0 144 LEU B N     1 ? ? 
ATOM   3133 C CA    . LEU B 1 163 ? 16.874  40.177 14.062 1.000 21.874  0 144 LEU B CA    1 ? ? 
ATOM   3134 C C     . LEU B 1 163 ? 16.447  40.225 12.597 1.000 23.252  0 144 LEU B C     1 ? ? 
ATOM   3135 O O     . LEU B 1 163 ? 17.209  39.839 11.710 1.000 21.788  0 144 LEU B O     1 ? ? 
ATOM   3136 C CB    . LEU B 1 163 ? 17.644  41.438 14.436 1.000 19.737  0 144 LEU B CB    1 ? ? 
ATOM   3137 C CG    . LEU B 1 163 ? 18.404  41.414 15.750 1.000 19.147  0 144 LEU B CG    1 ? ? 
ATOM   3138 C CD1   . LEU B 1 163 ? 19.271  42.645 15.807 1.000 19.204  0 144 LEU B CD1   1 ? ? 
ATOM   3139 C CD2   . LEU B 1 163 ? 17.441  41.432 16.920 1.000 18.434  0 144 LEU B CD2   1 ? ? 
ATOM   3140 N N     . CYS B 1 164 ? 15.221  40.702 12.358 1.000 23.635  0 145 CYS B N     1 ? ? 
ATOM   3141 C CA    . CYS B 1 164 ? 14.732  40.858 11.001 1.000 23.533  0 145 CYS B CA    1 ? ? 
ATOM   3142 C C     . CYS B 1 164 ? 13.714  41.988 10.982 1.000 23.233  0 145 CYS B C     1 ? ? 
ATOM   3143 O O     . CYS B 1 164 ? 12.767  41.954 11.760 1.000 22.766  0 145 CYS B O     1 ? ? 
ATOM   3144 C CB    . CYS B 1 164 ? 14.061  39.578 10.502 1.000 25.788  0 145 CYS B CB    1 ? ? 
ATOM   3145 S SG    . CYS B 1 164 ? 13.488  39.724 8.788  1.000 27.476  0 145 CYS B SG    1 ? ? 
ATOM   3146 N N     . ASP B 1 165 ? 13.902  42.938 10.052 1.000 24.638  0 146 ASP B N     1 ? ? 
ATOM   3147 C CA    . ASP B 1 165 ? 13.106  44.159 9.965  1.000 25.037  0 146 ASP B CA    1 ? ? 
ATOM   3148 C C     . ASP B 1 165 ? 12.582  44.370 8.536  1.000 26.413  0 146 ASP B C     1 ? ? 
ATOM   3149 O O     . ASP B 1 165 ? 12.495  45.499 8.047  1.000 29.543  0 146 ASP B O     1 ? ? 
ATOM   3150 C CB    . ASP B 1 165 ? 13.903  45.340 10.523 1.000 22.189  0 146 ASP B CB    1 ? ? 
ATOM   3151 C CG    . ASP B 1 165 ? 13.073  46.565 10.848 1.000 21.121  0 146 ASP B CG    1 ? ? 
ATOM   3152 O OD1   . ASP B 1 165 ? 11.849  46.435 10.938 1.000 20.901  0 146 ASP B OD1   1 ? ? 
ATOM   3153 O OD2   . ASP B 1 165 ? 13.669  47.648 10.980 1.000 20.313  0 146 ASP B OD2   1 ? ? 
ATOM   3154 N N     . ILE B 1 166 ? 12.225  43.270 7.862  1.000 27.630  0 147 ILE B N     1 ? ? 
ATOM   3155 C CA    . ILE B 1 166 ? 11.796  43.315 6.471  1.000 28.362  0 147 ILE B CA    1 ? ? 
ATOM   3156 C C     . ILE B 1 166 ? 10.270  43.361 6.414  1.000 28.867  0 147 ILE B C     1 ? ? 
ATOM   3157 O O     . ILE B 1 166 ? 9.598   42.697 7.201  1.000 32.005  0 147 ILE B O     1 ? ? 
ATOM   3158 C CB    . ILE B 1 166 ? 12.380  42.114 5.693  1.000 29.640  0 147 ILE B CB    1 ? ? 
ATOM   3159 C CG1   . ILE B 1 166 ? 13.905  42.226 5.564  1.000 28.679  0 147 ILE B CG1   1 ? ? 
ATOM   3160 C CG2   . ILE B 1 166 ? 11.694  41.918 4.339  1.000 29.182  0 147 ILE B CG2   1 ? ? 
ATOM   3161 C CD1   . ILE B 1 166 ? 14.613  40.905 5.254  1.000 26.985  0 147 ILE B CD1   1 ? ? 
ATOM   3162 N N     . GLY B 1 167 ? 9.738   44.103 5.434  1.000 28.376  0 148 GLY B N     1 ? ? 
ATOM   3163 C CA    . GLY B 1 167 ? 8.308   44.097 5.158  1.000 27.578  0 148 GLY B CA    1 ? ? 
ATOM   3164 C C     . GLY B 1 167 ? 7.871   45.409 4.519  1.000 28.594  0 148 GLY B C     1 ? ? 
ATOM   3165 O O     . GLY B 1 167 ? 7.792   46.442 5.185  1.000 27.161  0 148 GLY B O     1 ? ? 
ATOM   3166 N N     . GLU B 1 168 ? 7.597   45.352 3.214  1.000 30.193  0 149 GLU B N     1 ? ? 
ATOM   3167 C CA    . GLU B 1 168 ? 7.253   46.534 2.446  1.000 30.745  0 149 GLU B CA    1 ? ? 
ATOM   3168 C C     . GLU B 1 168 ? 5.742   46.732 2.454  1.000 31.720  0 149 GLU B C     1 ? ? 
ATOM   3169 O O     . GLU B 1 168 ? 4.982   45.817 2.139  1.000 30.902  0 149 GLU B O     1 ? ? 
ATOM   3170 C CB    . GLU B 1 168 ? 7.791   46.343 1.033  1.000 32.972  0 149 GLU B CB    1 ? ? 
ATOM   3171 C CG    . GLU B 1 168 ? 7.537   47.510 0.098  1.000 35.088  0 149 GLU B CG    1 ? ? 
ATOM   3172 C CD    . GLU B 1 168 ? 7.948   47.247 -1.341 1.000 36.313  0 149 GLU B CD    1 ? ? 
ATOM   3173 O OE1   . GLU B 1 168 ? 8.067   48.213 -2.074 1.000 39.450  0 149 GLU B OE1   1 ? ? 
ATOM   3174 O OE2   . GLU B 1 168 ? 8.188   46.084 -1.706 1.000 33.980  0 149 GLU B OE2   1 ? ? 
ATOM   3175 N N     . SER B 1 169 ? 5.323   47.947 2.805  1.000 33.238  0 150 SER B N     1 ? ? 
ATOM   3176 C CA    . SER B 1 169 ? 3.928   48.346 2.800  1.000 35.222  0 150 SER B CA    1 ? ? 
ATOM   3177 C C     . SER B 1 169 ? 3.332   48.286 1.390  1.000 37.658  0 150 SER B C     1 ? ? 
ATOM   3178 O O     . SER B 1 169 ? 4.041   48.270 0.384  1.000 37.769  0 150 SER B O     1 ? ? 
ATOM   3179 C CB    . SER B 1 169 ? 3.780   49.721 3.423  1.000 37.655  0 150 SER B CB    1 ? ? 
ATOM   3180 O OG    . SER B 1 169 ? 4.061   49.703 4.821  1.000 46.277  0 150 SER B OG    1 ? ? 
ATOM   3181 N N     . SER B 1 170 ? 2.007   48.170 1.331  1.000 37.771  0 151 SER B N     1 ? ? 
ATOM   3182 C CA    . SER B 1 170 ? 1.216   48.194 0.112  1.000 39.650  0 151 SER B CA    1 ? ? 
ATOM   3183 C C     . SER B 1 170 ? -0.191  48.613 0.501  1.000 40.708  0 151 SER B C     1 ? ? 
ATOM   3184 O O     . SER B 1 170 ? -0.619  48.306 1.605  1.000 41.819  0 151 SER B O     1 ? ? 
ATOM   3185 C CB    . SER B 1 170 ? 1.171   46.855 -0.584 1.000 40.365  0 151 SER B CB    1 ? ? 
ATOM   3186 O OG    . SER B 1 170 ? 0.064   46.820 -1.481 1.000 42.026  0 151 SER B OG    1 ? ? 
ATOM   3187 N N     . PRO B 1 171 ? -0.951  49.343 -0.352 1.000 40.126  0 152 PRO B N     1 ? ? 
ATOM   3188 C CA    . PRO B 1 171 ? -2.350  49.639 -0.030 1.000 39.668  0 152 PRO B CA    1 ? ? 
ATOM   3189 C C     . PRO B 1 171 ? -3.195  48.371 0.073  1.000 37.034  0 152 PRO B C     1 ? ? 
ATOM   3190 O O     . PRO B 1 171 ? -4.187  48.366 0.808  1.000 34.589  0 152 PRO B O     1 ? ? 
ATOM   3191 C CB    . PRO B 1 171 ? -2.835  50.552 -1.163 1.000 38.926  0 152 PRO B CB    1 ? ? 
ATOM   3192 C CG    . PRO B 1 171 ? -1.541  51.082 -1.792 1.000 39.557  0 152 PRO B CG    1 ? ? 
ATOM   3193 C CD    . PRO B 1 171 ? -0.515  49.981 -1.607 1.000 38.028  0 152 PRO B CD    1 ? ? 
ATOM   3194 N N     . SER B 1 172 ? -2.746  47.306 -0.609 1.000 33.319  0 153 SER B N     1 ? ? 
ATOM   3195 C CA    . SER B 1 172 ? -3.460  46.044 -0.626 1.000 32.771  0 153 SER B CA    1 ? ? 
ATOM   3196 C C     . SER B 1 172 ? -3.013  45.202 0.558  1.000 32.482  0 153 SER B C     1 ? ? 
ATOM   3197 O O     . SER B 1 172 ? -1.833  44.851 0.663  1.000 33.272  0 153 SER B O     1 ? ? 
ATOM   3198 C CB    . SER B 1 172 ? -3.247  45.307 -1.912 1.000 30.783  0 153 SER B CB    1 ? ? 
ATOM   3199 O OG    . SER B 1 172 ? -3.731  43.993 -1.784 1.000 30.775  0 153 SER B OG    1 ? ? 
ATOM   3200 N N     . PRO B 1 173 ? -3.942  44.833 1.469  1.000 32.266  0 154 PRO B N     1 ? ? 
ATOM   3201 C CA    . PRO B 1 173 ? -3.583  43.941 2.565  1.000 31.821  0 154 PRO B CA    1 ? ? 
ATOM   3202 C C     . PRO B 1 173 ? -3.284  42.517 2.098  1.000 33.022  0 154 PRO B C     1 ? ? 
ATOM   3203 O O     . PRO B 1 173 ? -2.527  41.812 2.755  1.000 30.996  0 154 PRO B O     1 ? ? 
ATOM   3204 C CB    . PRO B 1 173 ? -4.798  44.023 3.497  1.000 31.996  0 154 PRO B CB    1 ? ? 
ATOM   3205 C CG    . PRO B 1 173 ? -5.950  44.371 2.579  1.000 32.115  0 154 PRO B CG    1 ? ? 
ATOM   3206 C CD    . PRO B 1 173 ? -5.348  45.287 1.532  1.000 31.785  0 154 PRO B CD    1 ? ? 
ATOM   3207 N N     . THR B 1 174 ? -3.862  42.091 0.969  1.000 34.743  0 155 THR B N     1 ? ? 
ATOM   3208 C CA    . THR B 1 174 ? -3.566  40.762 0.446  1.000 35.294  0 155 THR B CA    1 ? ? 
ATOM   3209 C C     . THR B 1 174 ? -2.107  40.679 -0.015 1.000 31.954  0 155 THR B C     1 ? ? 
ATOM   3210 O O     . THR B 1 174 ? -1.451  39.649 0.122  1.000 30.181  0 155 THR B O     1 ? ? 
ATOM   3211 C CB    . THR B 1 174 ? -4.608  40.357 -0.609 1.000 38.992  0 155 THR B CB    1 ? ? 
ATOM   3212 O OG1   . THR B 1 174 ? -4.697  41.304 -1.680 1.000 45.275  0 155 THR B OG1   1 ? ? 
ATOM   3213 C CG2   . THR B 1 174 ? -6.002  40.320 -0.030 1.000 38.316  0 155 THR B CG2   1 ? ? 
ATOM   3214 N N     . VAL B 1 175 ? -1.614  41.779 -0.581 1.000 30.877  0 156 VAL B N     1 ? ? 
ATOM   3215 C CA    . VAL B 1 175 ? -0.235  41.849 -1.007 1.000 30.141  0 156 VAL B CA    1 ? ? 
ATOM   3216 C C     . VAL B 1 175 ? 0.646   41.776 0.236  1.000 28.644  0 156 VAL B C     1 ? ? 
ATOM   3217 O O     . VAL B 1 175 ? 1.558   40.934 0.327  1.000 26.566  0 156 VAL B O     1 ? ? 
ATOM   3218 C CB    . VAL B 1 175 ? -0.001  43.121 -1.838 1.000 31.098  0 156 VAL B CB    1 ? ? 
ATOM   3219 C CG1   . VAL B 1 175 ? 1.475   43.354 -2.070 1.000 29.972  0 156 VAL B CG1   1 ? ? 
ATOM   3220 C CG2   . VAL B 1 175 ? -0.737  43.061 -3.169 1.000 32.494  0 156 VAL B CG2   1 ? ? 
ATOM   3221 N N     . GLU B 1 176 ? 0.302   42.616 1.220  1.000 27.850  0 157 GLU B N     1 ? ? 
ATOM   3222 C CA    . GLU B 1 176 ? 1.029   42.662 2.479  1.000 29.115  0 157 GLU B CA    1 ? ? 
ATOM   3223 C C     . GLU B 1 176 ? 1.018   41.313 3.189  1.000 29.803  0 157 GLU B C     1 ? ? 
ATOM   3224 O O     . GLU B 1 176 ? 2.031   40.912 3.762  1.000 30.968  0 157 GLU B O     1 ? ? 
ATOM   3225 C CB    . GLU B 1 176 ? 0.424   43.736 3.368  1.000 29.127  0 157 GLU B CB    1 ? ? 
ATOM   3226 C CG    . GLU B 1 176 ? 0.781   45.135 2.906  1.000 27.949  0 157 GLU B CG    1 ? ? 
ATOM   3227 C CD    . GLU B 1 176 ? 0.344   46.152 3.940  1.000 28.136  0 157 GLU B CD    1 ? ? 
ATOM   3228 O OE1   . GLU B 1 176 ? -0.519  45.798 4.736  1.000 30.062  0 157 GLU B OE1   1 ? ? 
ATOM   3229 O OE2   . GLU B 1 176 ? 0.862   47.281 3.968  1.000 27.449  0 157 GLU B OE2   1 ? ? 
ATOM   3230 N N     . GLU B 1 177 ? -0.132  40.629 3.135  1.000 31.306  0 158 GLU B N     1 ? ? 
ATOM   3231 C CA    . GLU B 1 177 ? -0.299  39.284 3.670  1.000 32.645  0 158 GLU B CA    1 ? ? 
ATOM   3232 C C     . GLU B 1 177 ? 0.730   38.331 3.066  1.000 32.559  0 158 GLU B C     1 ? ? 
ATOM   3233 O O     . GLU B 1 177 ? 1.412   37.597 3.782  1.000 30.243  0 158 GLU B O     1 ? ? 
ATOM   3234 C CB    . GLU B 1 177 ? -1.730  38.808 3.408  1.000 35.013  0 158 GLU B CB    1 ? ? 
ATOM   3235 C CG    . GLU B 1 177 ? -1.950  37.333 3.643  1.000 40.640  0 158 GLU B CG    1 ? ? 
ATOM   3236 C CD    . GLU B 1 177 ? -3.395  36.877 3.644  1.000 43.544  0 158 GLU B CD    1 ? ? 
ATOM   3237 O OE1   . GLU B 1 177 ? -4.022  36.871 2.585  1.000 44.985  0 158 GLU B OE1   1 ? ? 
ATOM   3238 O OE2   . GLU B 1 177 ? -3.892  36.593 4.711  1.000 48.519  0 158 GLU B OE2   1 ? ? 
ATOM   3239 N N     . SER B 1 178 ? 0.881   38.391 1.743  1.000 32.921  0 159 SER B N     1 ? ? 
ATOM   3240 C CA    . SER B 1 178 ? 1.762   37.439 1.107  1.000 32.352  0 159 SER B CA    1 ? ? 
ATOM   3241 C C     . SER B 1 178 ? 3.222   37.747 1.440  1.000 29.813  0 159 SER B C     1 ? ? 
ATOM   3242 O O     . SER B 1 178 ? 3.978   36.831 1.757  1.000 30.030  0 159 SER B O     1 ? ? 
ATOM   3243 C CB    . SER B 1 178 ? 1.473   37.389 -0.351 1.000 34.844  0 159 SER B CB    1 ? ? 
ATOM   3244 O OG    . SER B 1 178 ? 2.068   38.462 -1.001 1.000 38.575  0 159 SER B OG    1 ? ? 
ATOM   3245 N N     . ARG B 1 179 ? 3.593   39.035 1.424  1.000 28.931  0 160 ARG B N     1 ? ? 
ATOM   3246 C CA    . ARG B 1 179 ? 4.920   39.482 1.838  1.000 29.285  0 160 ARG B CA    1 ? ? 
ATOM   3247 C C     . ARG B 1 179 ? 5.248   39.053 3.271  1.000 28.973  0 160 ARG B C     1 ? ? 
ATOM   3248 O O     . ARG B 1 179 ? 6.382   38.652 3.554  1.000 31.102  0 160 ARG B O     1 ? ? 
ATOM   3249 C CB    . ARG B 1 179 ? 5.057   41.001 1.692  1.000 28.569  0 160 ARG B CB    1 ? ? 
ATOM   3250 C CG    . ARG B 1 179 ? 5.147   41.466 0.246  1.000 29.800  0 160 ARG B CG    1 ? ? 
ATOM   3251 C CD    . ARG B 1 179 ? 5.200   42.975 0.178  1.000 32.575  0 160 ARG B CD    1 ? ? 
ATOM   3252 N NE    . ARG B 1 179 ? 5.054   43.472 -1.184 1.000 32.391  0 160 ARG B NE    1 ? ? 
ATOM   3253 C CZ    . ARG B 1 179 ? 4.680   44.711 -1.499 1.000 32.636  0 160 ARG B CZ    1 ? ? 
ATOM   3254 N NH1   . ARG B 1 179 ? 4.546   45.066 -2.751 1.000 32.066  0 160 ARG B NH1   1 ? ? 
ATOM   3255 N NH2   . ARG B 1 179 ? 4.299   45.581 -0.583 1.000 34.559  0 160 ARG B NH2   1 ? ? 
ATOM   3256 N N     . THR B 1 180 ? 4.253   39.136 4.164  1.000 27.466  0 161 THR B N     1 ? ? 
ATOM   3257 C CA    . THR B 1 180 ? 4.454   38.795 5.563  1.000 27.872  0 161 THR B CA    1 ? ? 
ATOM   3258 C C     . THR B 1 180 ? 4.746   37.301 5.699  1.000 28.397  0 161 THR B C     1 ? ? 
ATOM   3259 O O     . THR B 1 180 ? 5.720   36.928 6.348  1.000 30.406  0 161 THR B O     1 ? ? 
ATOM   3260 C CB    . THR B 1 180 ? 3.285   39.284 6.433  1.000 27.119  0 161 THR B CB    1 ? ? 
ATOM   3261 O OG1   . THR B 1 180 ? 3.094   40.688 6.265  1.000 25.138  0 161 THR B OG1   1 ? ? 
ATOM   3262 C CG2   . THR B 1 180 ? 3.487   39.015 7.908  1.000 26.658  0 161 THR B CG2   1 ? ? 
ATOM   3263 N N     . ILE B 1 181 ? 3.924   36.457 5.061  1.000 30.028  0 162 ILE B N     1 ? ? 
ATOM   3264 C CA    . ILE B 1 181 ? 4.080   35.005 5.132  1.000 33.806  0 162 ILE B CA    1 ? ? 
ATOM   3265 C C     . ILE B 1 181 ? 5.452   34.603 4.590  1.000 34.524  0 162 ILE B C     1 ? ? 
ATOM   3266 O O     . ILE B 1 181 ? 6.111   33.728 5.153  1.000 32.706  0 162 ILE B O     1 ? ? 
ATOM   3267 C CB    . ILE B 1 181 ? 2.918   34.273 4.428  1.000 35.682  0 162 ILE B CB    1 ? ? 
ATOM   3268 C CG1   . ILE B 1 181 ? 1.629   34.527 5.201  1.000 37.902  0 162 ILE B CG1   1 ? ? 
ATOM   3269 C CG2   . ILE B 1 181 ? 3.216   32.790 4.248  1.000 34.770  0 162 ILE B CG2   1 ? ? 
ATOM   3270 C CD1   . ILE B 1 181 ? 0.348   34.313 4.414  1.000 41.399  0 162 ILE B CD1   1 ? ? 
ATOM   3271 N N     . ARG B 1 182 ? 5.889   35.268 3.516  1.000 35.303  0 163 ARG B N     1 ? ? 
ATOM   3272 C CA    . ARG B 1 182 ? 7.176   34.951 2.931  1.000 36.086  0 163 ARG B CA    1 ? ? 
ATOM   3273 C C     . ARG B 1 182 ? 8.281   35.136 3.966  1.000 35.571  0 163 ARG B C     1 ? ? 
ATOM   3274 O O     . ARG B 1 182 ? 9.132   34.260 4.140  1.000 37.017  0 163 ARG B O     1 ? ? 
ATOM   3275 C CB    . ARG B 1 182 ? 7.441   35.848 1.731  1.000 39.974  0 163 ARG B CB    1 ? ? 
ATOM   3276 C CG    . ARG B 1 182 ? 8.268   35.138 0.691  1.000 43.506  0 163 ARG B CG    1 ? ? 
ATOM   3277 C CD    . ARG B 1 182 ? 8.711   36.117 -0.368 1.000 47.842  0 163 ARG B CD    1 ? ? 
ATOM   3278 N NE    . ARG B 1 182 ? 9.639   35.281 -1.105 1.000 49.813  0 163 ARG B NE    1 ? ? 
ATOM   3279 C CZ    . ARG B 1 182 ? 10.289  35.588 -2.215 1.000 51.442  0 163 ARG B CZ    1 ? ? 
ATOM   3280 N NH1   . ARG B 1 182 ? 11.055  34.667 -2.759 1.000 51.427  0 163 ARG B NH1   1 ? ? 
ATOM   3281 N NH2   . ARG B 1 182 ? 10.207  36.791 -2.765 1.000 52.603  0 163 ARG B NH2   1 ? ? 
ATOM   3282 N N     . VAL B 1 183 ? 8.229   36.276 4.657  1.000 34.422  0 164 VAL B N     1 ? ? 
ATOM   3283 C CA    . VAL B 1 183 ? 9.216   36.591 5.678  1.000 34.285  0 164 VAL B CA    1 ? ? 
ATOM   3284 C C     . VAL B 1 183 ? 9.159   35.553 6.792  1.000 33.901  0 164 VAL B C     1 ? ? 
ATOM   3285 O O     . VAL B 1 183 ? 10.201  35.123 7.265  1.000 30.811  0 164 VAL B O     1 ? ? 
ATOM   3286 C CB    . VAL B 1 183 ? 9.050   38.022 6.212  1.000 35.379  0 164 VAL B CB    1 ? ? 
ATOM   3287 C CG1   . VAL B 1 183 ? 9.804   38.232 7.519  1.000 32.646  0 164 VAL B CG1   1 ? ? 
ATOM   3288 C CG2   . VAL B 1 183 ? 9.490   39.036 5.164  1.000 34.092  0 164 VAL B CG2   1 ? ? 
ATOM   3289 N N     . LEU B 1 184 ? 7.942   35.154 7.183  1.000 33.976  0 165 LEU B N     1 ? ? 
ATOM   3290 C CA    . LEU B 1 184 ? 7.781   34.242 8.306  1.000 37.431  0 165 LEU B CA    1 ? ? 
ATOM   3291 C C     . LEU B 1 184 ? 8.313   32.857 7.954  1.000 39.626  0 165 LEU B C     1 ? ? 
ATOM   3292 O O     . LEU B 1 184 ? 8.863   32.163 8.816  1.000 37.521  0 165 LEU B O     1 ? ? 
ATOM   3293 C CB    . LEU B 1 184 ? 6.315   34.175 8.739  1.000 36.469  0 165 LEU B CB    1 ? ? 
ATOM   3294 C CG    . LEU B 1 184 ? 5.750   35.400 9.457  1.000 37.372  0 165 LEU B CG    1 ? ? 
ATOM   3295 C CD1   . LEU B 1 184 ? 4.298   35.118 9.800  1.000 37.924  0 165 LEU B CD1   1 ? ? 
ATOM   3296 C CD2   . LEU B 1 184 ? 6.554   35.760 10.712 1.000 36.950  0 165 LEU B CD2   1 ? ? 
ATOM   3297 N N     . LYS B 1 185 ? 8.123   32.441 6.694  1.000 44.499  0 166 LYS B N     1 ? ? 
ATOM   3298 C CA    . LYS B 1 185 ? 8.662   31.166 6.227  1.000 44.107  0 166 LYS B CA    1 ? ? 
ATOM   3299 C C     . LYS B 1 185 ? 10.192  31.214 6.249  1.000 39.886  0 166 LYS B C     1 ? ? 
ATOM   3300 O O     . LYS B 1 185 ? 10.843  30.267 6.714  1.000 35.190  0 166 LYS B O     1 ? ? 
ATOM   3301 C CB    . LYS B 1 185 ? 8.133   30.815 4.829  1.000 44.852  0 166 LYS B CB    1 ? ? 
ATOM   3302 C CG    . LYS B 1 185 ? 6.646   30.489 4.711  1.000 48.144  0 166 LYS B CG    1 ? ? 
ATOM   3303 C CD    . LYS B 1 185 ? 6.174   29.244 5.350  1.000 51.281  0 166 LYS B CD    1 ? ? 
ATOM   3304 C CE    . LYS B 1 185 ? 6.726   27.985 4.708  1.000 49.225  0 166 LYS B CE    1 ? ? 
ATOM   3305 N NZ    . LYS B 1 185 ? 6.733   26.867 5.676  1.000 43.534  0 166 LYS B NZ    1 ? ? 
ATOM   3306 N N     . MET B 1 186 ? 10.749  32.347 5.801  1.000 38.754  0 167 MET B N     1 ? ? 
ATOM   3307 C CA    . MET B 1 186 ? 12.187  32.535 5.709  1.000 40.063  0 167 MET B CA    1 ? ? 
ATOM   3308 C C     . MET B 1 186 ? 12.853  32.512 7.092  1.000 42.110  0 167 MET B C     1 ? ? 
ATOM   3309 O O     . MET B 1 186 ? 13.792  31.743 7.312  1.000 44.142  0 167 MET B O     1 ? ? 
ATOM   3310 C CB    . MET B 1 186 ? 12.481  33.833 4.956  1.000 39.454  0 167 MET B CB    1 ? ? 
ATOM   3311 C CG    . MET B 1 186 ? 13.949  34.157 4.794  1.000 41.430  0 167 MET B CG    1 ? ? 
ATOM   3312 S SD    . MET B 1 186 ? 14.575  35.169 6.153  1.000 41.520  0 167 MET B SD    1 ? ? 
ATOM   3313 C CE    . MET B 1 186 ? 13.754  36.721 5.797  1.000 38.074  0 167 MET B CE    1 ? ? 
ATOM   3314 N N     . VAL B 1 187 ? 12.315  33.263 8.064  1.000 42.222  0 168 VAL B N     1 ? ? 
ATOM   3315 C CA    . VAL B 1 187 ? 12.969  33.410 9.361  1.000 42.147  0 168 VAL B CA    1 ? ? 
ATOM   3316 C C     . VAL B 1 187 ? 12.982  32.097 10.139 1.000 41.940  0 168 VAL B C     1 ? ? 
ATOM   3317 O O     . VAL B 1 187 ? 13.895  31.866 10.925 1.000 44.181  0 168 VAL B O     1 ? ? 
ATOM   3318 C CB    . VAL B 1 187 ? 12.380  34.547 10.222 1.000 42.774  0 168 VAL B CB    1 ? ? 
ATOM   3319 C CG1   . VAL B 1 187 ? 12.476  35.913 9.563  1.000 43.017  0 168 VAL B CG1   1 ? ? 
ATOM   3320 C CG2   . VAL B 1 187 ? 10.956  34.274 10.661 1.000 43.881  0 168 VAL B CG2   1 ? ? 
ATOM   3321 N N     . GLU B 1 188 ? 11.983  31.239 9.916  1.000 42.452  0 169 GLU B N     1 ? ? 
ATOM   3322 C CA    . GLU B 1 188 ? 11.728  30.117 10.814 1.000 44.562  0 169 GLU B CA    1 ? ? 
ATOM   3323 C C     . GLU B 1 188 ? 12.983  29.268 11.013 1.000 41.932  0 169 GLU B C     1 ? ? 
ATOM   3324 O O     . GLU B 1 188 ? 13.383  29.044 12.143 1.000 40.913  0 169 GLU B O     1 ? ? 
ATOM   3325 C CB    . GLU B 1 188 ? 10.436  29.430 10.352 1.000 45.531  0 169 GLU B CB    1 ? ? 
ATOM   3326 C CG    . GLU B 1 188 ? 10.316  27.931 10.426 1.000 47.788  0 169 GLU B CG    1 ? ? 
ATOM   3327 C CD    . GLU B 1 188 ? 10.503  27.235 11.737 1.000 50.901  0 169 GLU B CD    1 ? ? 
ATOM   3328 O OE1   . GLU B 1 188 ? 11.625  27.147 12.260 1.000 51.698  0 169 GLU B OE1   1 ? ? 
ATOM   3329 O OE2   . GLU B 1 188 ? 9.501   26.701 12.192 1.000 54.296  0 169 GLU B OE2   1 ? ? 
ATOM   3330 N N     . PRO B 1 189 ? 13.657  28.804 9.936  1.000 40.090  0 170 PRO B N     1 ? ? 
ATOM   3331 C CA    . PRO B 1 189 ? 14.850  27.960 10.079 1.000 38.797  0 170 PRO B CA    1 ? ? 
ATOM   3332 C C     . PRO B 1 189 ? 16.038  28.600 10.788 1.000 35.969  0 170 PRO B C     1 ? ? 
ATOM   3333 O O     . PRO B 1 189 ? 16.988  27.919 11.113 1.000 34.319  0 170 PRO B O     1 ? ? 
ATOM   3334 C CB    . PRO B 1 189 ? 15.256  27.655 8.632  1.000 38.232  0 170 PRO B CB    1 ? ? 
ATOM   3335 C CG    . PRO B 1 189 ? 13.980  27.846 7.844  1.000 36.882  0 170 PRO B CG    1 ? ? 
ATOM   3336 C CD    . PRO B 1 189 ? 13.268  28.987 8.531  1.000 36.887  0 170 PRO B CD    1 ? ? 
ATOM   3337 N N     . TRP B 1 190 ? 15.976  29.906 11.026 1.000 35.408  0 171 TRP B N     1 ? ? 
ATOM   3338 C CA    . TRP B 1 190 ? 17.031  30.587 11.757 1.000 35.502  0 171 TRP B CA    1 ? ? 
ATOM   3339 C C     . TRP B 1 190 ? 16.801  30.483 13.260 1.000 35.728  0 171 TRP B C     1 ? ? 
ATOM   3340 O O     . TRP B 1 190 ? 17.709  30.804 14.031 1.000 34.846  0 171 TRP B O     1 ? ? 
ATOM   3341 C CB    . TRP B 1 190 ? 17.080  32.064 11.370 1.000 33.863  0 171 TRP B CB    1 ? ? 
ATOM   3342 C CG    . TRP B 1 190 ? 17.513  32.365 9.975  1.000 33.781  0 171 TRP B CG    1 ? ? 
ATOM   3343 C CD1   . TRP B 1 190 ? 16.741  32.322 8.855  1.000 33.581  0 171 TRP B CD1   1 ? ? 
ATOM   3344 C CD2   . TRP B 1 190 ? 18.805  32.849 9.567  1.000 35.289  0 171 TRP B CD2   1 ? ? 
ATOM   3345 N NE1   . TRP B 1 190 ? 17.468  32.716 7.770  1.000 34.312  0 171 TRP B NE1   1 ? ? 
ATOM   3346 C CE2   . TRP B 1 190 ? 18.733  33.060 8.173  1.000 36.342  0 171 TRP B CE2   1 ? ? 
ATOM   3347 C CE3   . TRP B 1 190 ? 20.005  33.119 10.234 1.000 34.401  0 171 TRP B CE3   1 ? ? 
ATOM   3348 C CZ2   . TRP B 1 190 ? 19.822  33.503 7.423  1.000 37.132  0 171 TRP B CZ2   1 ? ? 
ATOM   3349 C CZ3   . TRP B 1 190 ? 21.067  33.591 9.495  1.000 37.503  0 171 TRP B CZ3   1 ? ? 
ATOM   3350 C CH2   . TRP B 1 190 ? 20.978  33.776 8.115  1.000 37.953  0 171 TRP B CH2   1 ? ? 
ATOM   3351 N N     . LEU B 1 191 ? 15.587  30.074 13.666 1.000 35.866  0 172 LEU B N     1 ? ? 
ATOM   3352 C CA    . LEU B 1 191 ? 15.183  30.168 15.063 1.000 37.090  0 172 LEU B CA    1 ? ? 
ATOM   3353 C C     . LEU B 1 191 ? 15.390  28.823 15.743 1.000 38.250  0 172 LEU B C     1 ? ? 
ATOM   3354 O O     . LEU B 1 191 ? 14.811  27.827 15.343 1.000 45.445  0 172 LEU B O     1 ? ? 
ATOM   3355 C CB    . LEU B 1 191 ? 13.705  30.560 15.138 1.000 35.184  0 172 LEU B CB    1 ? ? 
ATOM   3356 C CG    . LEU B 1 191 ? 13.357  31.841 14.377 1.000 35.242  0 172 LEU B CG    1 ? ? 
ATOM   3357 C CD1   . LEU B 1 191 ? 11.894  32.190 14.550 1.000 34.691  0 172 LEU B CD1   1 ? ? 
ATOM   3358 C CD2   . LEU B 1 191 ? 14.273  32.958 14.847 1.000 36.086  0 172 LEU B CD2   1 ? ? 
ATOM   3359 N N     . LYS B 1 192 ? 16.215  28.803 16.787 1.000 37.823  0 173 LYS B N     1 ? ? 
ATOM   3360 C CA    . LYS B 1 192 ? 16.547  27.585 17.502 1.000 38.503  0 173 LYS B CA    1 ? ? 
ATOM   3361 C C     . LYS B 1 192 ? 16.950  27.995 18.913 1.000 35.970  0 173 LYS B C     1 ? ? 
ATOM   3362 O O     . LYS B 1 192 ? 18.129  28.173 19.220 1.000 34.513  0 173 LYS B O     1 ? ? 
ATOM   3363 C CB    . LYS B 1 192 ? 17.721  26.851 16.840 1.000 44.492  0 173 LYS B CB    1 ? ? 
ATOM   3364 C CG    . LYS B 1 192 ? 17.514  26.371 15.411 1.000 46.939  0 173 LYS B CG    1 ? ? 
ATOM   3365 C CD    . LYS B 1 192 ? 16.820  25.024 15.265 1.000 49.111  0 173 LYS B CD    1 ? ? 
ATOM   3366 C CE    . LYS B 1 192 ? 16.680  24.730 13.784 1.000 54.312  0 173 LYS B CE    1 ? ? 
ATOM   3367 N NZ    . LYS B 1 192 ? 18.003  24.896 13.151 1.000 59.090  0 173 LYS B NZ    1 ? ? 
ATOM   3368 N N     . ASN B 1 193 ? 15.942  28.147 19.776 1.000 35.217  0 174 ASN B N     1 ? ? 
ATOM   3369 C CA    . ASN B 1 193 ? 16.154  28.568 21.155 1.000 33.482  0 174 ASN B CA    1 ? ? 
ATOM   3370 C C     . ASN B 1 193 ? 17.173  29.704 21.226 1.000 32.606  0 174 ASN B C     1 ? ? 
ATOM   3371 O O     . ASN B 1 193 ? 18.125  29.648 22.001 1.000 30.933  0 174 ASN B O     1 ? ? 
ATOM   3372 C CB    . ASN B 1 193 ? 16.549  27.396 22.061 1.000 33.627  0 174 ASN B CB    1 ? ? 
ATOM   3373 C CG    . ASN B 1 193 ? 15.588  26.229 21.985 1.000 34.023  0 174 ASN B CG    1 ? ? 
ATOM   3374 O OD1   . ASN B 1 193 ? 15.893  25.221 21.354 1.000 35.320  0 174 ASN B OD1   1 ? ? 
ATOM   3375 N ND2   . ASN B 1 193 ? 14.416  26.368 22.583 1.000 35.280  0 174 ASN B ND2   1 ? ? 
ATOM   3376 N N     . ASN B 1 194 ? 16.991  30.704 20.364 1.000 31.556  0 175 ASN B N     1 ? ? 
ATOM   3377 C CA    . ASN B 1 194 ? 17.806  31.908 20.396 1.000 31.612  0 175 ASN B CA    1 ? ? 
ATOM   3378 C C     . ASN B 1 194 ? 16.905  33.098 20.743 1.000 31.149  0 175 ASN B C     1 ? ? 
ATOM   3379 O O     . ASN B 1 194 ? 15.683  32.964 20.862 1.000 32.310  0 175 ASN B O     1 ? ? 
ATOM   3380 C CB    . ASN B 1 194 ? 18.638  32.056 19.113 1.000 31.682  0 175 ASN B CB    1 ? ? 
ATOM   3381 C CG    . ASN B 1 194 ? 17.845  31.778 17.847 1.000 34.176  0 175 ASN B CG    1 ? ? 
ATOM   3382 O OD1   . ASN B 1 194 ? 16.627  31.600 17.875 1.000 34.509  0 175 ASN B OD1   1 ? ? 
ATOM   3383 N ND2   . ASN B 1 194 ? 18.509  31.779 16.708 1.000 33.752  0 175 ASN B ND2   1 ? ? 
ATOM   3384 N N     . GLN B 1 195 ? 17.528  34.261 20.944 1.000 29.860  0 176 GLN B N     1 ? ? 
ATOM   3385 C CA    . GLN B 1 195 ? 16.791  35.506 21.058 1.000 28.093  0 176 GLN B CA    1 ? ? 
ATOM   3386 C C     . GLN B 1 195 ? 16.403  35.989 19.662 1.000 27.449  0 176 GLN B C     1 ? ? 
ATOM   3387 O O     . GLN B 1 195 ? 17.166  35.837 18.709 1.000 26.900  0 176 GLN B O     1 ? ? 
ATOM   3388 C CB    . GLN B 1 195 ? 17.675  36.522 21.769 1.000 26.742  0 176 GLN B CB    1 ? ? 
ATOM   3389 C CG    . GLN B 1 195 ? 17.863  36.171 23.231 1.000 27.264  0 176 GLN B CG    1 ? ? 
ATOM   3390 C CD    . GLN B 1 195 ? 16.644  36.573 24.019 1.000 28.441  0 176 GLN B CD    1 ? ? 
ATOM   3391 O OE1   . GLN B 1 195 ? 16.332  37.741 24.111 1.000 29.935  0 176 GLN B OE1   1 ? ? 
ATOM   3392 N NE2   . GLN B 1 195 ? 15.947  35.616 24.612 1.000 26.719  0 176 GLN B NE2   1 ? ? 
ATOM   3393 N N     . PHE B 1 196 ? 15.223  36.609 19.552 1.000 24.445  0 177 PHE B N     1 ? ? 
ATOM   3394 C CA    . PHE B 1 196 ? 14.821  37.128 18.263 1.000 22.495  0 177 PHE B CA    1 ? ? 
ATOM   3395 C C     . PHE B 1 196 ? 13.906  38.347 18.367 1.000 21.727  0 177 PHE B C     1 ? ? 
ATOM   3396 O O     . PHE B 1 196 ? 13.295  38.619 19.396 1.000 21.609  0 177 PHE B O     1 ? ? 
ATOM   3397 C CB    . PHE B 1 196 ? 14.228  36.029 17.390 1.000 22.548  0 177 PHE B CB    1 ? ? 
ATOM   3398 C CG    . PHE B 1 196 ? 13.016  35.324 17.947 1.000 24.020  0 177 PHE B CG    1 ? ? 
ATOM   3399 C CD1   . PHE B 1 196 ? 11.745  35.876 17.850 1.000 23.496  0 177 PHE B CD1   1 ? ? 
ATOM   3400 C CD2   . PHE B 1 196 ? 13.130  34.054 18.491 1.000 23.159  0 177 PHE B CD2   1 ? ? 
ATOM   3401 C CE1   . PHE B 1 196 ? 10.627  35.189 18.315 1.000 22.307  0 177 PHE B CE1   1 ? ? 
ATOM   3402 C CE2   . PHE B 1 196 ? 12.025  33.376 18.969 1.000 21.590  0 177 PHE B CE2   1 ? ? 
ATOM   3403 C CZ    . PHE B 1 196 ? 10.778  33.951 18.889 1.000 21.682  0 177 PHE B CZ    1 ? ? 
ATOM   3404 N N     . CYS B 1 197 ? 13.829  39.074 17.251 1.000 20.342  0 178 CYS B N     1 ? ? 
ATOM   3405 C CA    . CYS B 1 197 ? 12.922  40.189 17.074 1.000 19.355  0 178 CYS B CA    1 ? ? 
ATOM   3406 C C     . CYS B 1 197 ? 12.683  40.351 15.577 1.000 19.457  0 178 CYS B C     1 ? ? 
ATOM   3407 O O     . CYS B 1 197 ? 13.595  40.737 14.859 1.000 18.930  0 178 CYS B O     1 ? ? 
ATOM   3408 C CB    . CYS B 1 197 ? 13.548  41.445 17.652 1.000 19.004  0 178 CYS B CB    1 ? ? 
ATOM   3409 S SG    . CYS B 1 197 ? 12.488  42.899 17.485 1.000 20.302  0 178 CYS B SG    1 ? ? 
ATOM   3410 N N     . ILE B 1 198 ? 11.462  40.031 15.129 1.000 20.549  0 179 ILE B N     1 ? ? 
ATOM   3411 C CA    . ILE B 1 198 ? 11.100  39.923 13.725 1.000 21.345  0 179 ILE B CA    1 ? ? 
ATOM   3412 C C     . ILE B 1 198 ? 9.861   40.771 13.441 1.000 21.430  0 179 ILE B C     1 ? ? 
ATOM   3413 O O     . ILE B 1 198 ? 8.804   40.612 14.056 1.000 19.961  0 179 ILE B O     1 ? ? 
ATOM   3414 C CB    . ILE B 1 198 ? 10.851  38.449 13.349 1.000 22.929  0 179 ILE B CB    1 ? ? 
ATOM   3415 C CG1   . ILE B 1 198 ? 12.082  37.583 13.603 1.000 22.943  0 179 ILE B CG1   1 ? ? 
ATOM   3416 C CG2   . ILE B 1 198 ? 10.383  38.311 11.902 1.000 23.064  0 179 ILE B CG2   1 ? ? 
ATOM   3417 C CD1   . ILE B 1 198 ? 11.713  36.254 14.182 1.000 24.078  0 179 ILE B CD1   1 ? ? 
ATOM   3418 N N     . LYS B 1 199 ? 9.985   41.643 12.444 1.000 22.271  0 180 LYS B N     1 ? ? 
ATOM   3419 C CA    . LYS B 1 199 ? 8.869   42.452 12.004 1.000 22.968  0 180 LYS B CA    1 ? ? 
ATOM   3420 C C     . LYS B 1 199 ? 7.787   41.577 11.378 1.000 23.848  0 180 LYS B C     1 ? ? 
ATOM   3421 O O     . LYS B 1 199 ? 8.047   40.665 10.587 1.000 25.130  0 180 LYS B O     1 ? ? 
ATOM   3422 C CB    . LYS B 1 199 ? 9.329   43.477 10.973 1.000 23.311  0 180 LYS B CB    1 ? ? 
ATOM   3423 C CG    . LYS B 1 199 ? 8.337   44.588 10.687 1.000 24.042  0 180 LYS B CG    1 ? ? 
ATOM   3424 C CD    . LYS B 1 199 ? 8.903   45.361 9.540  1.000 24.421  0 180 LYS B CD    1 ? ? 
ATOM   3425 C CE    . LYS B 1 199 ? 7.900   45.893 8.556  1.000 25.259  0 180 LYS B CE    1 ? ? 
ATOM   3426 N NZ    . LYS B 1 199 ? 8.458   47.129 7.945  1.000 26.611  0 180 LYS B NZ    1 ? ? 
ATOM   3427 N N     . VAL B 1 200 ? 6.553   41.852 11.793 1.000 22.517  0 181 VAL B N     1 ? ? 
ATOM   3428 C CA    . VAL B 1 200 ? 5.400   41.287 11.133 1.000 21.600  0 181 VAL B CA    1 ? ? 
ATOM   3429 C C     . VAL B 1 200 ? 4.624   42.439 10.506 1.000 21.178  0 181 VAL B C     1 ? ? 
ATOM   3430 O O     . VAL B 1 200 ? 3.905   43.153 11.203 1.000 20.463  0 181 VAL B O     1 ? ? 
ATOM   3431 C CB    . VAL B 1 200 ? 4.543   40.469 12.108 1.000 21.805  0 181 VAL B CB    1 ? ? 
ATOM   3432 C CG1   . VAL B 1 200 ? 3.397   39.770 11.382 1.000 21.738  0 181 VAL B CG1   1 ? ? 
ATOM   3433 C CG2   . VAL B 1 200 ? 5.411   39.459 12.840 1.000 21.566  0 181 VAL B CG2   1 ? ? 
ATOM   3434 N N     . LEU B 1 201 ? 4.769   42.588 9.180  1.000 19.451  0 182 LEU B N     1 ? ? 
ATOM   3435 C CA    . LEU B 1 201 ? 4.294   43.777 8.495  1.000 18.636  0 182 LEU B CA    1 ? ? 
ATOM   3436 C C     . LEU B 1 201 ? 2.781   43.897 8.613  1.000 19.735  0 182 LEU B C     1 ? ? 
ATOM   3437 O O     . LEU B 1 201 ? 2.278   44.978 8.912  1.000 20.891  0 182 LEU B O     1 ? ? 
ATOM   3438 C CB    . LEU B 1 201 ? 4.706   43.710 7.024  1.000 17.674  0 182 LEU B CB    1 ? ? 
ATOM   3439 C CG    . LEU B 1 201 ? 3.938   44.641 6.080  1.000 16.365  0 182 LEU B CG    1 ? ? 
ATOM   3440 C CD1   . LEU B 1 201 ? 4.445   46.069 6.154  1.000 15.181  0 182 LEU B CD1   1 ? ? 
ATOM   3441 C CD2   . LEU B 1 201 ? 3.992   44.106 4.662  1.000 16.680  0 182 LEU B CD2   1 ? ? 
ATOM   3442 N N     . ASN B 1 202 ? 2.095   42.780 8.337  1.000 20.234  0 183 ASN B N     1 ? ? 
ATOM   3443 C CA    . ASN B 1 202 ? 0.648   42.679 8.396  1.000 20.301  0 183 ASN B CA    1 ? ? 
ATOM   3444 C C     . ASN B 1 202 ? 0.277   41.512 9.303  1.000 19.879  0 183 ASN B C     1 ? ? 
ATOM   3445 O O     . ASN B 1 202 ? 0.246   40.374 8.847  1.000 18.155  0 183 ASN B O     1 ? ? 
ATOM   3446 C CB    . ASN B 1 202 ? 0.012   42.502 7.011  1.000 21.492  0 183 ASN B CB    1 ? ? 
ATOM   3447 C CG    . ASN B 1 202 ? -1.499  42.612 7.069  1.000 22.351  0 183 ASN B CG    1 ? ? 
ATOM   3448 O OD1   . ASN B 1 202 ? -2.121  42.026 7.954  1.000 24.321  0 183 ASN B OD1   1 ? ? 
ATOM   3449 N ND2   . ASN B 1 202 ? -2.086  43.363 6.150  1.000 21.835  0 183 ASN B ND2   1 ? ? 
ATOM   3450 N N     . PRO B 1 203 ? -0.009  41.761 10.604 1.000 20.276  0 184 PRO B N     1 ? ? 
ATOM   3451 C CA    . PRO B 1 203 ? -0.360  40.677 11.515 1.000 21.416  0 184 PRO B CA    1 ? ? 
ATOM   3452 C C     . PRO B 1 203 ? -1.852  40.403 11.704 1.000 23.232  0 184 PRO B C     1 ? ? 
ATOM   3453 O O     . PRO B 1 203 ? -2.229  39.549 12.503 1.000 23.173  0 184 PRO B O     1 ? ? 
ATOM   3454 C CB    . PRO B 1 203 ? 0.257   41.212 12.806 1.000 20.496  0 184 PRO B CB    1 ? ? 
ATOM   3455 C CG    . PRO B 1 203 ? -0.032  42.691 12.754 1.000 19.437  0 184 PRO B CG    1 ? ? 
ATOM   3456 C CD    . PRO B 1 203 ? 0.081   43.061 11.292 1.000 19.256  0 184 PRO B CD    1 ? ? 
ATOM   3457 N N     . TYR B 1 204 ? -2.708  41.120 10.975 1.000 25.594  0 185 TYR B N     1 ? ? 
ATOM   3458 C CA    . TYR B 1 204 ? -4.137  41.017 11.238 1.000 28.613  0 185 TYR B CA    1 ? ? 
ATOM   3459 C C     . TYR B 1 204 ? -4.876  40.146 10.227 1.000 31.576  0 185 TYR B C     1 ? ? 
ATOM   3460 O O     . TYR B 1 204 ? -6.018  39.794 10.490 1.000 34.362  0 185 TYR B O     1 ? ? 
ATOM   3461 C CB    . TYR B 1 204 ? -4.809  42.391 11.317 1.000 26.898  0 185 TYR B CB    1 ? ? 
ATOM   3462 C CG    . TYR B 1 204 ? -4.571  43.269 10.116 1.000 27.548  0 185 TYR B CG    1 ? ? 
ATOM   3463 C CD1   . TYR B 1 204 ? -5.289  43.071 8.941  1.000 25.366  0 185 TYR B CD1   1 ? ? 
ATOM   3464 C CD2   . TYR B 1 204 ? -3.606  44.280 10.147 1.000 26.395  0 185 TYR B CD2   1 ? ? 
ATOM   3465 C CE1   . TYR B 1 204 ? -5.050  43.843 7.822  1.000 24.673  0 185 TYR B CE1   1 ? ? 
ATOM   3466 C CE2   . TYR B 1 204 ? -3.371  45.073 9.036  1.000 25.367  0 185 TYR B CE2   1 ? ? 
ATOM   3467 C CZ    . TYR B 1 204 ? -4.107  44.854 7.880  1.000 25.871  0 185 TYR B CZ    1 ? ? 
ATOM   3468 O OH    . TYR B 1 204 ? -3.901  45.615 6.774  1.000 25.847  0 185 TYR B OH    1 ? ? 
ATOM   3469 N N     . MET B 1 205 ? -4.256  39.819 9.084  1.000 31.934  0 186 MET B N     1 ? ? 
ATOM   3470 C CA    . MET B 1 205 ? -4.927  38.984 8.098  1.000 30.835  0 186 MET B CA    1 ? ? 
ATOM   3471 C C     . MET B 1 205 ? -5.016  37.557 8.628  1.000 31.496  0 186 MET B C     1 ? ? 
ATOM   3472 O O     . MET B 1 205 ? -4.042  37.034 9.166  1.000 31.357  0 186 MET B O     1 ? ? 
ATOM   3473 C CB    . MET B 1 205 ? -4.179  38.985 6.760  1.000 29.884  0 186 MET B CB    1 ? ? 
ATOM   3474 C CG    . MET B 1 205 ? -4.162  40.334 6.074  1.000 29.952  0 186 MET B CG    1 ? ? 
ATOM   3475 S SD    . MET B 1 205 ? -5.806  40.980 5.672  1.000 32.328  0 186 MET B SD    1 ? ? 
ATOM   3476 C CE    . MET B 1 205 ? -6.181  39.962 4.245  1.000 30.173  0 186 MET B CE    1 ? ? 
ATOM   3477 N N     . PRO B 1 206 ? -6.177  36.879 8.476  1.000 32.910  0 187 PRO B N     1 ? ? 
ATOM   3478 C CA    . PRO B 1 206 ? -6.380  35.553 9.053  1.000 33.027  0 187 PRO B CA    1 ? ? 
ATOM   3479 C C     . PRO B 1 206 ? -5.298  34.516 8.779  1.000 33.711  0 187 PRO B C     1 ? ? 
ATOM   3480 O O     . PRO B 1 206 ? -4.976  33.735 9.669  1.000 33.571  0 187 PRO B O     1 ? ? 
ATOM   3481 C CB    . PRO B 1 206 ? -7.718  35.138 8.443  1.000 30.326  0 187 PRO B CB    1 ? ? 
ATOM   3482 C CG    . PRO B 1 206 ? -8.455  36.453 8.342  1.000 30.660  0 187 PRO B CG    1 ? ? 
ATOM   3483 C CD    . PRO B 1 206 ? -7.391  37.387 7.816  1.000 30.503  0 187 PRO B CD    1 ? ? 
ATOM   3484 N N     . THR B 1 207 ? -4.752  34.488 7.561  1.000 32.709  0 188 THR B N     1 ? ? 
ATOM   3485 C CA    . THR B 1 207 ? -3.761  33.466 7.241  1.000 31.831  0 188 THR B CA    1 ? ? 
ATOM   3486 C C     . THR B 1 207 ? -2.463  33.727 7.999  1.000 27.909  0 188 THR B C     1 ? ? 
ATOM   3487 O O     . THR B 1 207 ? -1.792  32.794 8.427  1.000 27.418  0 188 THR B O     1 ? ? 
ATOM   3488 C CB    . THR B 1 207 ? -3.353  33.498 5.759  1.000 35.810  0 188 THR B CB    1 ? ? 
ATOM   3489 O OG1   . THR B 1 207 ? -4.334  34.011 4.845  1.000 41.204  0 188 THR B OG1   1 ? ? 
ATOM   3490 C CG2   . THR B 1 207 ? -2.650  32.256 5.260  1.000 36.730  0 188 THR B CG2   1 ? ? 
ATOM   3491 N N     . VAL B 1 208 ? -2.103  34.998 8.173  1.000 27.671  0 189 VAL B N     1 ? ? 
ATOM   3492 C CA    . VAL B 1 208 ? -0.914  35.342 8.937  1.000 27.368  0 189 VAL B CA    1 ? ? 
ATOM   3493 C C     . VAL B 1 208 ? -1.072  34.941 10.404 1.000 27.312  0 189 VAL B C     1 ? ? 
ATOM   3494 O O     . VAL B 1 208 ? -0.147  34.423 11.022 1.000 27.601  0 189 VAL B O     1 ? ? 
ATOM   3495 C CB    . VAL B 1 208 ? -0.608  36.842 8.809  1.000 27.533  0 189 VAL B CB    1 ? ? 
ATOM   3496 C CG1   . VAL B 1 208 ? 0.589   37.220 9.662  1.000 24.061  0 189 VAL B CG1   1 ? ? 
ATOM   3497 C CG2   . VAL B 1 208 ? -0.370  37.232 7.353  1.000 27.493  0 189 VAL B CG2   1 ? ? 
ATOM   3498 N N     . ILE B 1 209 ? -2.223  35.273 10.988 1.000 28.345  0 190 ILE B N     1 ? ? 
ATOM   3499 C CA    . ILE B 1 209 ? -2.573  34.886 12.348 1.000 30.028  0 190 ILE B CA    1 ? ? 
ATOM   3500 C C     . ILE B 1 209 ? -2.372  33.381 12.545 1.000 31.835  0 190 ILE B C     1 ? ? 
ATOM   3501 O O     . ILE B 1 209 ? -1.834  32.943 13.557 1.000 32.909  0 190 ILE B O     1 ? ? 
ATOM   3502 C CB    . ILE B 1 209 ? -4.021  35.315 12.654 1.000 28.601  0 190 ILE B CB    1 ? ? 
ATOM   3503 C CG1   . ILE B 1 209 ? -4.153  36.834 12.747 1.000 26.909  0 190 ILE B CG1   1 ? ? 
ATOM   3504 C CG2   . ILE B 1 209 ? -4.532  34.626 13.903 1.000 30.571  0 190 ILE B CG2   1 ? ? 
ATOM   3505 C CD1   . ILE B 1 209 ? -3.832  37.384 14.102 1.000 28.818  0 190 ILE B CD1   1 ? ? 
ATOM   3506 N N     . GLU B 1 210 ? -2.851  32.591 11.584 1.000 33.151  0 191 GLU B N     1 ? ? 
ATOM   3507 C CA    . GLU B 1 210 ? -2.722  31.146 11.626 1.000 35.112  0 191 GLU B CA    1 ? ? 
ATOM   3508 C C     . GLU B 1 210 ? -1.238  30.768 11.650 1.000 33.735  0 191 GLU B C     1 ? ? 
ATOM   3509 O O     . GLU B 1 210 ? -0.825  29.984 12.498 1.000 33.088  0 191 GLU B O     1 ? ? 
ATOM   3510 C CB    . GLU B 1 210 ? -3.511  30.537 10.456 1.000 37.362  0 191 GLU B CB    1 ? ? 
ATOM   3511 C CG    . GLU B 1 210 ? -3.798  29.046 10.567 1.000 45.086  0 191 GLU B CG    1 ? ? 
ATOM   3512 C CD    . GLU B 1 210 ? -3.264  28.255 9.385  1.000 50.863  0 191 GLU B CD    1 ? ? 
ATOM   3513 O OE1   . GLU B 1 210 ? -2.756  28.919 8.426  1.000 59.969  0 191 GLU B OE1   1 ? ? 
ATOM   3514 O OE2   . GLU B 1 210 ? -3.303  27.012 9.436  1.000 54.559  0 191 GLU B OE2   1 ? ? 
ATOM   3515 N N     . HIS B 1 211 ? -0.427  31.374 10.771 1.000 31.228  0 192 HIS B N     1 ? ? 
ATOM   3516 C CA    . HIS B 1 211 ? 0.988   31.042 10.741 1.000 30.521  0 192 HIS B CA    1 ? ? 
ATOM   3517 C C     . HIS B 1 211 ? 1.666   31.446 12.042 1.000 28.060  0 192 HIS B C     1 ? ? 
ATOM   3518 O O     . HIS B 1 211 ? 2.552   30.744 12.506 1.000 29.260  0 192 HIS B O     1 ? ? 
ATOM   3519 C CB    . HIS B 1 211 ? 1.683   31.738 9.580  1.000 33.247  0 192 HIS B CB    1 ? ? 
ATOM   3520 C CG    . HIS B 1 211 ? 1.554   31.007 8.292  1.000 39.623  0 192 HIS B CG    1 ? ? 
ATOM   3521 N ND1   . HIS B 1 211 ? 2.394   29.978 7.950  1.000 41.368  0 192 HIS B ND1   1 ? ? 
ATOM   3522 C CD2   . HIS B 1 211 ? 0.677   31.135 7.273  1.000 42.930  0 192 HIS B CD2   1 ? ? 
ATOM   3523 C CE1   . HIS B 1 211 ? 2.041   29.504 6.766  1.000 42.383  0 192 HIS B CE1   1 ? ? 
ATOM   3524 N NE2   . HIS B 1 211 ? 0.991   30.210 6.321  1.000 41.713  0 192 HIS B NE2   1 ? ? 
ATOM   3525 N N     . LEU B 1 212 ? 1.307   32.611 12.581 1.000 25.987  0 193 LEU B N     1 ? ? 
ATOM   3526 C CA    . LEU B 1 212 ? 1.920   33.113 13.803 1.000 26.577  0 193 LEU B CA    1 ? ? 
ATOM   3527 C C     . LEU B 1 212 ? 1.595   32.195 14.976 1.000 26.117  0 193 LEU B C     1 ? ? 
ATOM   3528 O O     . LEU B 1 212 ? 2.363   32.050 15.921 1.000 23.389  0 193 LEU B O     1 ? ? 
ATOM   3529 C CB    . LEU B 1 212 ? 1.391   34.527 14.068 1.000 26.519  0 193 LEU B CB    1 ? ? 
ATOM   3530 C CG    . LEU B 1 212 ? 2.037   35.605 13.205 1.000 26.938  0 193 LEU B CG    1 ? ? 
ATOM   3531 C CD1   . LEU B 1 212 ? 1.335   36.937 13.350 1.000 25.683  0 193 LEU B CD1   1 ? ? 
ATOM   3532 C CD2   . LEU B 1 212 ? 3.500   35.760 13.591 1.000 26.302  0 193 LEU B CD2   1 ? ? 
ATOM   3533 N N     . GLU B 1 213 ? 0.384   31.656 14.954 1.000 29.196  0 194 GLU B N     1 ? ? 
ATOM   3534 C CA    . GLU B 1 213 ? -0.076  30.783 16.020 1.000 33.522  0 194 GLU B CA    1 ? ? 
ATOM   3535 C C     . GLU B 1 213 ? 0.771   29.516 16.027 1.000 33.077  0 194 GLU B C     1 ? ? 
ATOM   3536 O O     . GLU B 1 213 ? 1.194   29.069 17.088 1.000 32.263  0 194 GLU B O     1 ? ? 
ATOM   3537 C CB    . GLU B 1 213 ? -1.547  30.445 15.771 1.000 36.632  0 194 GLU B CB    1 ? ? 
ATOM   3538 C CG    . GLU B 1 213 ? -2.471  30.808 16.879 1.000 38.685  0 194 GLU B CG    1 ? ? 
ATOM   3539 C CD    . GLU B 1 213 ? -3.395  32.001 16.818 1.000 40.669  0 194 GLU B CD    1 ? ? 
ATOM   3540 O OE1   . GLU B 1 213 ? -3.054  32.904 17.530 1.000 43.494  0 194 GLU B OE1   1 ? ? 
ATOM   3541 O OE2   . GLU B 1 213 ? -4.483  32.007 16.238 1.000 37.729  0 194 GLU B OE2   1 ? ? 
ATOM   3542 N N     . ARG B 1 214 ? 1.027   28.967 14.832 1.000 34.487  0 195 ARG B N     1 ? ? 
ATOM   3543 C CA    . ARG B 1 214 ? 1.852   27.779 14.684 1.000 34.976  0 195 ARG B CA    1 ? ? 
ATOM   3544 C C     . ARG B 1 214 ? 3.283   28.088 15.132 1.000 33.952  0 195 ARG B C     1 ? ? 
ATOM   3545 O O     . ARG B 1 214 ? 3.916   27.303 15.846 1.000 34.009  0 195 ARG B O     1 ? ? 
ATOM   3546 C CB    . ARG B 1 214 ? 1.871   27.372 13.211 1.000 38.390  0 195 ARG B CB    1 ? ? 
ATOM   3547 C CG    . ARG B 1 214 ? 2.393   25.973 12.972 1.000 43.153  0 195 ARG B CG    1 ? ? 
ATOM   3548 C CD    . ARG B 1 214 ? 2.500   25.756 11.481 1.000 47.314  0 195 ARG B CD    1 ? ? 
ATOM   3549 N NE    . ARG B 1 214 ? 2.856   26.974 10.800 1.000 52.794  0 195 ARG B NE    1 ? ? 
ATOM   3550 C CZ    . ARG B 1 214 ? 4.081   27.376 10.545 1.000 54.887  0 195 ARG B CZ    1 ? ? 
ATOM   3551 N NH1   . ARG B 1 214 ? 5.116   26.674 10.967 1.000 56.663  0 195 ARG B NH1   1 ? ? 
ATOM   3552 N NH2   . ARG B 1 214 ? 4.224   28.516 9.895  1.000 57.139  0 195 ARG B NH2   1 ? ? 
ATOM   3553 N N     . LEU B 1 215 ? 3.801   29.250 14.728 1.000 30.839  0 196 LEU B N     1 ? ? 
ATOM   3554 C CA    . LEU B 1 215 ? 5.176   29.579 15.058 1.000 29.078  0 196 LEU B CA    1 ? ? 
ATOM   3555 C C     . LEU B 1 215 ? 5.346   29.755 16.566 1.000 27.393  0 196 LEU B C     1 ? ? 
ATOM   3556 O O     . LEU B 1 215 ? 6.334   29.300 17.146 1.000 26.408  0 196 LEU B O     1 ? ? 
ATOM   3557 C CB    . LEU B 1 215 ? 5.592   30.834 14.288 1.000 29.780  0 196 LEU B CB    1 ? ? 
ATOM   3558 C CG    . LEU B 1 215 ? 5.799   30.597 12.794 1.000 31.791  0 196 LEU B CG    1 ? ? 
ATOM   3559 C CD1   . LEU B 1 215 ? 5.790   31.908 12.033 1.000 30.524  0 196 LEU B CD1   1 ? ? 
ATOM   3560 C CD2   . LEU B 1 215 ? 7.101   29.861 12.547 1.000 31.593  0 196 LEU B CD2   1 ? ? 
ATOM   3561 N N     . GLN B 1 216 ? 4.366   30.401 17.207 1.000 26.203  0 197 GLN B N     1 ? ? 
ATOM   3562 C CA    . GLN B 1 216 ? 4.432   30.665 18.637 1.000 27.502  0 197 GLN B CA    1 ? ? 
ATOM   3563 C C     . GLN B 1 216 ? 4.397   29.341 19.397 1.000 27.155  0 197 GLN B C     1 ? ? 
ATOM   3564 O O     . GLN B 1 216 ? 5.075   29.207 20.413 1.000 26.279  0 197 GLN B O     1 ? ? 
ATOM   3565 C CB    . GLN B 1 216 ? 3.276   31.562 19.073 1.000 28.338  0 197 GLN B CB    1 ? ? 
ATOM   3566 C CG    . GLN B 1 216 ? 3.328   31.976 20.536 1.000 29.411  0 197 GLN B CG    1 ? ? 
ATOM   3567 C CD    . GLN B 1 216 ? 2.027   32.597 20.978 1.000 31.747  0 197 GLN B CD    1 ? ? 
ATOM   3568 O OE1   . GLN B 1 216 ? 0.941   32.099 20.686 1.000 33.572  0 197 GLN B OE1   1 ? ? 
ATOM   3569 N NE2   . GLN B 1 216 ? 2.124   33.694 21.710 1.000 28.634  0 197 GLN B NE2   1 ? ? 
ATOM   3570 N N     . ARG B 1 217 ? 3.614   28.378 18.901 1.000 26.162  0 198 ARG B N     1 ? ? 
ATOM   3571 C CA    . ARG B 1 217 ? 3.544   27.058 19.513 1.000 27.388  0 198 ARG B CA    1 ? ? 
ATOM   3572 C C     . ARG B 1 217 ? 4.893   26.351 19.442 1.000 26.670  0 198 ARG B C     1 ? ? 
ATOM   3573 O O     . ARG B 1 217 ? 5.261   25.628 20.355 1.000 27.192  0 198 ARG B O     1 ? ? 
ATOM   3574 C CB    . ARG B 1 217 ? 2.440   26.216 18.868 1.000 27.317  0 198 ARG B CB    1 ? ? 
ATOM   3575 C CG    . ARG B 1 217 ? 1.053   26.558 19.403 1.000 26.578  0 198 ARG B CG    1 ? ? 
ATOM   3576 C CD    . ARG B 1 217 ? -0.090  25.650 19.007 1.000 26.830  0 198 ARG B CD    1 ? ? 
ATOM   3577 N NE    . ARG B 1 217 ? -0.185  25.425 17.569 1.000 28.742  0 198 ARG B NE    1 ? ? 
ATOM   3578 C CZ    . ARG B 1 217 ? -0.872  26.179 16.706 1.000 28.820  0 198 ARG B CZ    1 ? ? 
ATOM   3579 N NH1   . ARG B 1 217 ? -1.505  27.272 17.127 1.000 30.616  0 198 ARG B NH1   1 ? ? 
ATOM   3580 N NH2   . ARG B 1 217 ? -0.862  25.876 15.414 1.000 26.436  0 198 ARG B NH2   1 ? ? 
ATOM   3581 N N     . LYS B 1 218 ? 5.622   26.549 18.348 1.000 27.461  0 199 LYS B N     1 ? ? 
ATOM   3582 C CA    . LYS B 1 218 ? 6.912   25.895 18.194 1.000 29.110  0 199 LYS B CA    1 ? ? 
ATOM   3583 C C     . LYS B 1 218 ? 7.997   26.669 18.947 1.000 31.006  0 199 LYS B C     1 ? ? 
ATOM   3584 O O     . LYS B 1 218 ? 8.762   26.066 19.702 1.000 33.603  0 199 LYS B O     1 ? ? 
ATOM   3585 C CB    . LYS B 1 218 ? 7.245   25.778 16.706 1.000 28.343  0 199 LYS B CB    1 ? ? 
ATOM   3586 C CG    . LYS B 1 218 ? 8.417   24.892 16.365 1.000 28.399  0 199 LYS B CG    1 ? ? 
ATOM   3587 C CD    . LYS B 1 218 ? 8.412   24.640 14.887 1.000 29.334  0 199 LYS B CD    1 ? ? 
ATOM   3588 C CE    . LYS B 1 218 ? 9.695   24.025 14.388 1.000 30.831  0 199 LYS B CE    1 ? ? 
ATOM   3589 N NZ    . LYS B 1 218 ? 9.755   24.059 12.907 1.000 31.020  0 199 LYS B NZ    1 ? ? 
ATOM   3590 N N     . HIS B 1 219 ? 8.025   28.005 18.776 1.000 29.257  0 200 HIS B N     1 ? ? 
ATOM   3591 C CA    . HIS B 1 219 ? 9.171   28.790 19.207 1.000 27.702  0 200 HIS B CA    1 ? ? 
ATOM   3592 C C     . HIS B 1 219 ? 8.886   29.739 20.366 1.000 27.596  0 200 HIS B C     1 ? ? 
ATOM   3593 O O     . HIS B 1 219 ? 9.816   30.345 20.894 1.000 27.680  0 200 HIS B O     1 ? ? 
ATOM   3594 C CB    . HIS B 1 219 ? 9.746   29.591 18.049 1.000 25.858  0 200 HIS B CB    1 ? ? 
ATOM   3595 C CG    . HIS B 1 219 ? 10.389  28.708 17.057 1.000 25.917  0 200 HIS B CG    1 ? ? 
ATOM   3596 N ND1   . HIS B 1 219 ? 10.084  28.715 15.740 1.000 25.098  0 200 HIS B ND1   1 ? ? 
ATOM   3597 C CD2   . HIS B 1 219 ? 11.338  27.773 17.206 1.000 26.285  0 200 HIS B CD2   1 ? ? 
ATOM   3598 C CE1   . HIS B 1 219 ? 10.824  27.826 15.125 1.000 25.792  0 200 HIS B CE1   1 ? ? 
ATOM   3599 N NE2   . HIS B 1 219 ? 11.594  27.261 15.974 1.000 27.696  0 200 HIS B NE2   1 ? ? 
ATOM   3600 N N     . GLY B 1 220 ? 7.611   29.894 20.725 1.000 29.121  0 201 GLY B N     1 ? ? 
ATOM   3601 C CA    . GLY B 1 220 ? 7.244   30.792 21.809 1.000 29.886  0 201 GLY B CA    1 ? ? 
ATOM   3602 C C     . GLY B 1 220 ? 7.248   32.258 21.375 1.000 30.584  0 201 GLY B C     1 ? ? 
ATOM   3603 O O     . GLY B 1 220 ? 6.955   32.584 20.222 1.000 33.015  0 201 GLY B O     1 ? ? 
ATOM   3604 N N     . GLY B 1 221 ? 7.577   33.148 22.316 1.000 28.431  0 202 GLY B N     1 ? ? 
ATOM   3605 C CA    . GLY B 1 221 ? 7.529   34.572 22.056 1.000 26.804  0 202 GLY B CA    1 ? ? 
ATOM   3606 C C     . GLY B 1 221 ? 6.102   35.112 21.967 1.000 25.757  0 202 GLY B C     1 ? ? 
ATOM   3607 O O     . GLY B 1 221 ? 5.132   34.391 22.195 1.000 24.753  0 202 GLY B O     1 ? ? 
ATOM   3608 N N     . MET B 1 222 ? 6.016   36.399 21.607 1.000 26.522  0 203 MET B N     1 ? ? 
ATOM   3609 C CA    . MET B 1 222 ? 4.812   37.215 21.650 1.000 26.772  0 203 MET B CA    1 ? ? 
ATOM   3610 C C     . MET B 1 222 ? 4.947   38.324 20.605 1.000 24.592  0 203 MET B C     1 ? ? 
ATOM   3611 O O     . MET B 1 222 ? 6.059   38.708 20.237 1.000 23.589  0 203 MET B O     1 ? ? 
ATOM   3612 C CB    . MET B 1 222 ? 4.630   37.834 23.046 1.000 29.416  0 203 MET B CB    1 ? ? 
ATOM   3613 C CG    . MET B 1 222 ? 3.218   38.264 23.376 1.000 36.025  0 203 MET B CG    1 ? ? 
ATOM   3614 S SD    . MET B 1 222 ? 1.978   37.328 22.466 1.000 50.381  0 203 MET B SD    1 ? ? 
ATOM   3615 C CE    . MET B 1 222 ? 0.578   38.434 22.575 1.000 43.916  0 203 MET B CE    1 ? ? 
ATOM   3616 N N     . LEU B 1 223 ? 3.802   38.823 20.125 1.000 21.906  0 204 LEU B N     1 ? ? 
ATOM   3617 C CA    . LEU B 1 223 ? 3.764   40.015 19.288 1.000 21.992  0 204 LEU B CA    1 ? ? 
ATOM   3618 C C     . LEU B 1 223 ? 3.620   41.269 20.147 1.000 20.309  0 204 LEU B C     1 ? ? 
ATOM   3619 O O     . LEU B 1 223 ? 2.874   41.282 21.122 1.000 20.571  0 204 LEU B O     1 ? ? 
ATOM   3620 C CB    . LEU B 1 223 ? 2.629   39.908 18.264 1.000 21.359  0 204 LEU B CB    1 ? ? 
ATOM   3621 C CG    . LEU B 1 223 ? 3.043   39.361 16.897 1.000 21.993  0 204 LEU B CG    1 ? ? 
ATOM   3622 C CD1   . LEU B 1 223 ? 3.489   37.910 16.972 1.000 23.725  0 204 LEU B CD1   1 ? ? 
ATOM   3623 C CD2   . LEU B 1 223 ? 1.897   39.505 15.939 1.000 22.154  0 204 LEU B CD2   1 ? ? 
ATOM   3624 N N     . VAL B 1 224 ? 4.354   42.321 19.755 1.000 19.871  0 205 VAL B N     1 ? ? 
ATOM   3625 C CA    . VAL B 1 224 ? 4.381   43.577 20.487 1.000 19.292  0 205 VAL B CA    1 ? ? 
ATOM   3626 C C     . VAL B 1 224 ? 4.323   44.749 19.505 1.000 18.716  0 205 VAL B C     1 ? ? 
ATOM   3627 O O     . VAL B 1 224 ? 4.789   44.659 18.359 1.000 19.144  0 205 VAL B O     1 ? ? 
ATOM   3628 C CB    . VAL B 1 224 ? 5.635   43.673 21.362 1.000 19.069  0 205 VAL B CB    1 ? ? 
ATOM   3629 C CG1   . VAL B 1 224 ? 5.658   44.975 22.137 1.000 19.057  0 205 VAL B CG1   1 ? ? 
ATOM   3630 C CG2   . VAL B 1 224 ? 5.754   42.494 22.297 1.000 18.629  0 205 VAL B CG2   1 ? ? 
ATOM   3631 N N     . ARG B 1 225 ? 3.693   45.835 19.959 1.000 17.476  0 206 ARG B N     1 ? ? 
ATOM   3632 C CA    . ARG B 1 225 ? 3.571   47.084 19.235 1.000 16.968  0 206 ARG B CA    1 ? ? 
ATOM   3633 C C     . ARG B 1 225 ? 4.588   48.081 19.777 1.000 17.487  0 206 ARG B C     1 ? ? 
ATOM   3634 O O     . ARG B 1 225 ? 4.656   48.368 20.970 1.000 18.249  0 206 ARG B O     1 ? ? 
ATOM   3635 C CB    . ARG B 1 225 ? 2.172   47.695 19.418 1.000 16.932  0 206 ARG B CB    1 ? ? 
ATOM   3636 C CG    . ARG B 1 225 ? 1.961   49.020 18.694 1.000 16.959  0 206 ARG B CG    1 ? ? 
ATOM   3637 C CD    . ARG B 1 225 ? 2.064   48.931 17.169 1.000 16.590  0 206 ARG B CD    1 ? ? 
ATOM   3638 N NE    . ARG B 1 225 ? 1.888   50.210 16.497 1.000 16.059  0 206 ARG B NE    1 ? ? 
ATOM   3639 C CZ    . ARG B 1 225 ? 1.684   50.354 15.188 1.000 15.408  0 206 ARG B CZ    1 ? ? 
ATOM   3640 N NH1   . ARG B 1 225 ? 1.654   49.289 14.401 1.000 14.958  0 206 ARG B NH1   1 ? ? 
ATOM   3641 N NH2   . ARG B 1 225 ? 1.503   51.561 14.678 1.000 14.982  0 206 ARG B NH2   1 ? ? 
ATOM   3642 N N     . ASN B 1 226 ? 5.391   48.622 18.870 1.000 18.217  0 207 ASN B N     1 ? ? 
ATOM   3643 C CA    . ASN B 1 226 ? 6.380   49.603 19.256 1.000 17.755  0 207 ASN B CA    1 ? ? 
ATOM   3644 C C     . ASN B 1 226 ? 5.768   50.991 19.135 1.000 17.391  0 207 ASN B C     1 ? ? 
ATOM   3645 O O     . ASN B 1 226 ? 5.423   51.393 18.041 1.000 16.936  0 207 ASN B O     1 ? ? 
ATOM   3646 C CB    . ASN B 1 226 ? 7.625   49.451 18.384 1.000 17.985  0 207 ASN B CB    1 ? ? 
ATOM   3647 C CG    . ASN B 1 226 ? 8.787   50.271 18.863 1.000 18.625  0 207 ASN B CG    1 ? ? 
ATOM   3648 O OD1   . ASN B 1 226 ? 8.639   51.451 19.157 1.000 20.207  0 207 ASN B OD1   1 ? ? 
ATOM   3649 N ND2   . ASN B 1 226 ? 9.953   49.652 18.938 1.000 18.792  0 207 ASN B ND2   1 ? ? 
ATOM   3650 N N     . PRO B 1 227 ? 5.729   51.805 20.216 1.000 17.403  0 208 PRO B N     1 ? ? 
ATOM   3651 C CA    . PRO B 1 227 ? 5.126   53.131 20.163 1.000 17.277  0 208 PRO B CA    1 ? ? 
ATOM   3652 C C     . PRO B 1 227 ? 5.783   54.108 19.191 1.000 17.501  0 208 PRO B C     1 ? ? 
ATOM   3653 O O     . PRO B 1 227 ? 5.165   55.115 18.859 1.000 17.533  0 208 PRO B O     1 ? ? 
ATOM   3654 C CB    . PRO B 1 227 ? 5.248   53.652 21.604 1.000 16.760  0 208 PRO B CB    1 ? ? 
ATOM   3655 C CG    . PRO B 1 227 ? 6.315   52.823 22.256 1.000 17.069  0 208 PRO B CG    1 ? ? 
ATOM   3656 C CD    . PRO B 1 227 ? 6.230   51.479 21.558 1.000 17.556  0 208 PRO B CD    1 ? ? 
ATOM   3657 N N     . LEU B 1 228 ? 7.013   53.802 18.754 1.000 16.703  0 209 LEU B N     1 ? ? 
ATOM   3658 C CA    . LEU B 1 228 ? 7.716   54.612 17.768 1.000 16.424  0 209 LEU B CA    1 ? ? 
ATOM   3659 C C     . LEU B 1 228 ? 7.257   54.282 16.346 1.000 16.179  0 209 LEU B C     1 ? ? 
ATOM   3660 O O     . LEU B 1 228 ? 7.686   54.951 15.398 1.000 15.802  0 209 LEU B O     1 ? ? 
ATOM   3661 C CB    . LEU B 1 228 ? 9.221   54.386 17.910 1.000 16.134  0 209 LEU B CB    1 ? ? 
ATOM   3662 C CG    . LEU B 1 228 ? 9.857   54.937 19.185 1.000 16.687  0 209 LEU B CG    1 ? ? 
ATOM   3663 C CD1   . LEU B 1 228 ? 10.996  54.081 19.618 1.000 17.632  0 209 LEU B CD1   1 ? ? 
ATOM   3664 C CD2   . LEU B 1 228 ? 10.397  56.334 18.969 1.000 16.863  0 209 LEU B CD2   1 ? ? 
ATOM   3665 N N     . SER B 1 229 ? 6.397   53.251 16.220 1.000 15.989  0 210 SER B N     1 ? ? 
ATOM   3666 C CA    . SER B 1 229 ? 5.740   52.922 14.959 1.000 16.404  0 210 SER B CA    1 ? ? 
ATOM   3667 C C     . SER B 1 229 ? 4.668   53.960 14.636 1.000 17.743  0 210 SER B C     1 ? ? 
ATOM   3668 O O     . SER B 1 229 ? 3.976   54.440 15.538 1.000 16.829  0 210 SER B O     1 ? ? 
ATOM   3669 C CB    . SER B 1 229 ? 5.103   51.565 14.968 1.000 14.999  0 210 SER B CB    1 ? ? 
ATOM   3670 O OG    . SER B 1 229 ? 6.062   50.543 15.102 1.000 15.362  0 210 SER B OG    1 ? ? 
ATOM   3671 N N     . ARG B 1 230 ? 4.538   54.277 13.335 1.000 19.056  0 211 ARG B N     1 ? ? 
ATOM   3672 C CA    . ARG B 1 230 ? 3.573   55.264 12.904 1.000 20.882  0 211 ARG B CA    1 ? ? 
ATOM   3673 C C     . ARG B 1 230 ? 2.208   54.596 12.789 1.000 20.853  0 211 ARG B C     1 ? ? 
ATOM   3674 O O     . ARG B 1 230 ? 2.096   53.390 12.548 1.000 20.655  0 211 ARG B O     1 ? ? 
ATOM   3675 C CB    . ARG B 1 230 ? 4.020   55.879 11.583 1.000 24.093  0 211 ARG B CB    1 ? ? 
ATOM   3676 C CG    . ARG B 1 230 ? 4.967   57.047 11.788 1.000 26.791  0 211 ARG B CG    1 ? ? 
ATOM   3677 C CD    . ARG B 1 230 ? 5.646   57.353 10.481 1.000 29.600  0 211 ARG B CD    1 ? ? 
ATOM   3678 N NE    . ARG B 1 230 ? 6.972   57.806 10.849 1.000 35.261  0 211 ARG B NE    1 ? ? 
ATOM   3679 C CZ    . ARG B 1 230 ? 7.767   58.576 10.140 1.000 33.514  0 211 ARG B CZ    1 ? ? 
ATOM   3680 N NH1   . ARG B 1 230 ? 8.935   58.859 10.642 1.000 33.532  0 211 ARG B NH1   1 ? ? 
ATOM   3681 N NH2   . ARG B 1 230 ? 7.386   59.141 9.005  1.000 33.470  0 211 ARG B NH2   1 ? ? 
ATOM   3682 N N     . ASN B 1 231 ? 1.165   55.411 12.931 1.000 20.898  0 212 ASN B N     1 ? ? 
ATOM   3683 C CA    . ASN B 1 231 ? -0.183  54.895 12.877 1.000 22.751  0 212 ASN B CA    1 ? ? 
ATOM   3684 C C     . ASN B 1 231 ? -0.485  54.373 11.473 1.000 24.863  0 212 ASN B C     1 ? ? 
ATOM   3685 O O     . ASN B 1 231 ? -1.434  53.606 11.316 1.000 26.925  0 212 ASN B O     1 ? ? 
ATOM   3686 C CB    . ASN B 1 231 ? -1.164  55.989 13.273 1.000 22.188  0 212 ASN B CB    1 ? ? 
ATOM   3687 C CG    . ASN B 1 231 ? -1.019  56.459 14.708 1.000 21.428  0 212 ASN B CG    1 ? ? 
ATOM   3688 O OD1   . ASN B 1 231 ? -0.736  55.678 15.611 1.000 20.940  0 212 ASN B OD1   1 ? ? 
ATOM   3689 N ND2   . ASN B 1 231 ? -1.202  57.750 14.927 1.000 21.473  0 212 ASN B ND2   1 ? ? 
ATOM   3690 N N     . SER B 1 232 ? 0.315   54.799 10.481 1.000 24.621  0 213 SER B N     1 ? ? 
ATOM   3691 C CA    . SER B 1 232 ? 0.209   54.438 9.077  1.000 23.169  0 213 SER B CA    1 ? ? 
ATOM   3692 C C     . SER B 1 232 ? 0.568   52.970 8.813  1.000 22.812  0 213 SER B C     1 ? ? 
ATOM   3693 O O     . SER B 1 232 ? 0.414   52.484 7.694  1.000 24.654  0 213 SER B O     1 ? ? 
ATOM   3694 C CB    . SER B 1 232 ? 1.066   55.361 8.245  1.000 24.381  0 213 SER B CB    1 ? ? 
ATOM   3695 O OG    . SER B 1 232 ? 2.393   55.447 8.753  1.000 23.985  0 213 SER B OG    1 ? ? 
ATOM   3696 N N     . THR B 1 233 ? 1.089   52.260 9.817  1.000 21.639  0 214 THR B N     1 ? ? 
ATOM   3697 C CA    . THR B 1 233 ? 1.440   50.857 9.630  1.000 20.995  0 214 THR B CA    1 ? ? 
ATOM   3698 C C     . THR B 1 233 ? 0.965   50.078 10.846 1.000 20.794  0 214 THR B C     1 ? ? 
ATOM   3699 O O     . THR B 1 233 ? 0.989   50.597 11.961 1.000 20.580  0 214 THR B O     1 ? ? 
ATOM   3700 C CB    . THR B 1 233 ? 2.946   50.625 9.453  1.000 20.905  0 214 THR B CB    1 ? ? 
ATOM   3701 O OG1   . THR B 1 233 ? 3.171   49.212 9.510  1.000 20.760  0 214 THR B OG1   1 ? ? 
ATOM   3702 C CG2   . THR B 1 233 ? 3.749   51.318 10.533 1.000 20.575  0 214 THR B CG2   1 ? ? 
ATOM   3703 N N     . HIS B 1 234 ? 0.543   48.838 10.590 1.000 20.587  0 215 HIS B N     1 ? ? 
ATOM   3704 C CA    . HIS B 1 234 ? 0.035   47.941 11.617 1.000 20.630  0 215 HIS B CA    1 ? ? 
ATOM   3705 C C     . HIS B 1 234 ? 1.135   46.979 12.052 1.000 19.635  0 215 HIS B C     1 ? ? 
ATOM   3706 O O     . HIS B 1 234 ? 0.855   46.033 12.785 1.000 19.286  0 215 HIS B O     1 ? ? 
ATOM   3707 C CB    . HIS B 1 234 ? -1.161  47.140 11.069 1.000 20.171  0 215 HIS B CB    1 ? ? 
ATOM   3708 C CG    . HIS B 1 234 ? -2.160  46.723 12.094 1.000 20.080  0 215 HIS B CG    1 ? ? 
ATOM   3709 N ND1   . HIS B 1 234 ? -1.856  45.817 13.082 1.000 20.018  0 215 HIS B ND1   1 ? ? 
ATOM   3710 C CD2   . HIS B 1 234 ? -3.458  47.049 12.267 1.000 20.276  0 215 HIS B CD2   1 ? ? 
ATOM   3711 C CE1   . HIS B 1 234 ? -2.920  45.619 13.827 1.000 20.332  0 215 HIS B CE1   1 ? ? 
ATOM   3712 N NE2   . HIS B 1 234 ? -3.923  46.349 13.341 1.000 20.185  0 215 HIS B NE2   1 ? ? 
ATOM   3713 N N     . GLU B 1 235 ? 2.377   47.227 11.600 1.000 18.367  0 216 GLU B N     1 ? ? 
ATOM   3714 C CA    . GLU B 1 235 ? 3.496   46.370 11.949 1.000 18.056  0 216 GLU B CA    1 ? ? 
ATOM   3715 C C     . GLU B 1 235 ? 3.542   46.101 13.457 1.000 17.705  0 216 GLU B C     1 ? ? 
ATOM   3716 O O     . GLU B 1 235 ? 3.354   46.998 14.286 1.000 16.576  0 216 GLU B O     1 ? ? 
ATOM   3717 C CB    . GLU B 1 235 ? 4.812   46.999 11.507 1.000 17.846  0 216 GLU B CB    1 ? ? 
ATOM   3718 C CG    . GLU B 1 235 ? 5.090   48.266 12.250 1.000 17.972  0 216 GLU B CG    1 ? ? 
ATOM   3719 C CD    . GLU B 1 235 ? 6.325   49.118 12.042 1.000 18.204  0 216 GLU B CD    1 ? ? 
ATOM   3720 O OE1   . GLU B 1 235 ? 6.621   49.822 12.964 1.000 18.110  0 216 GLU B OE1   1 ? ? 
ATOM   3721 O OE2   . GLU B 1 235 ? 6.972   49.123 11.030 1.000 18.802  0 216 GLU B OE2   1 ? ? 
ATOM   3722 N N     . MET B 1 236 ? 3.803   44.833 13.781 1.000 17.714  0 217 MET B N     1 ? ? 
ATOM   3723 C CA    . MET B 1 236 ? 4.114   44.411 15.128 1.000 18.173  0 217 MET B CA    1 ? ? 
ATOM   3724 C C     . MET B 1 236 ? 5.332   43.502 15.051 1.000 18.474  0 217 MET B C     1 ? ? 
ATOM   3725 O O     . MET B 1 236 ? 5.699   43.005 13.987 1.000 18.198  0 217 MET B O     1 ? ? 
ATOM   3726 C CB    . MET B 1 236 ? 2.919   43.667 15.728 1.000 18.366  0 217 MET B CB    1 ? ? 
ATOM   3727 C CG    . MET B 1 236 ? 1.728   44.586 15.958 1.000 17.822  0 217 MET B CG    1 ? ? 
ATOM   3728 S SD    . MET B 1 236 ? 0.279   43.708 16.603 1.000 17.490  0 217 MET B SD    1 ? ? 
ATOM   3729 C CE    . MET B 1 236 ? 0.857   43.387 18.270 1.000 16.950  0 217 MET B CE    1 ? ? 
ATOM   3730 N N     . TYR B 1 237 ? 6.007   43.343 16.180 1.000 19.492  0 218 TYR B N     1 ? ? 
ATOM   3731 C CA    . TYR B 1 237 ? 7.246   42.601 16.191 1.000 20.968  0 218 TYR B CA    1 ? ? 
ATOM   3732 C C     . TYR B 1 237 ? 7.052   41.341 17.024 1.000 22.002  0 218 TYR B C     1 ? ? 
ATOM   3733 O O     . TYR B 1 237 ? 6.574   41.383 18.155 1.000 23.167  0 218 TYR B O     1 ? ? 
ATOM   3734 C CB    . TYR B 1 237 ? 8.374   43.505 16.700 1.000 22.486  0 218 TYR B CB    1 ? ? 
ATOM   3735 C CG    . TYR B 1 237 ? 8.805   44.551 15.699 1.000 23.308  0 218 TYR B CG    1 ? ? 
ATOM   3736 C CD1   . TYR B 1 237 ? 8.027   45.672 15.473 1.000 24.327  0 218 TYR B CD1   1 ? ? 
ATOM   3737 C CD2   . TYR B 1 237 ? 9.981   44.428 14.983 1.000 23.913  0 218 TYR B CD2   1 ? ? 
ATOM   3738 C CE1   . TYR B 1 237 ? 8.391   46.647 14.561 1.000 26.975  0 218 TYR B CE1   1 ? ? 
ATOM   3739 C CE2   . TYR B 1 237 ? 10.363  45.391 14.062 1.000 25.457  0 218 TYR B CE2   1 ? ? 
ATOM   3740 C CZ    . TYR B 1 237 ? 9.556   46.494 13.838 1.000 26.707  0 218 TYR B CZ    1 ? ? 
ATOM   3741 O OH    . TYR B 1 237 ? 9.887   47.465 12.946 1.000 26.616  0 218 TYR B OH    1 ? ? 
ATOM   3742 N N     . TRP B 1 238 ? 7.410   40.205 16.427 1.000 21.717  0 219 TRP B N     1 ? ? 
ATOM   3743 C CA    . TRP B 1 238 ? 7.442   38.942 17.134 1.000 21.521  0 219 TRP B CA    1 ? ? 
ATOM   3744 C C     . TRP B 1 238 ? 8.764   38.878 17.890 1.000 21.559  0 219 TRP B C     1 ? ? 
ATOM   3745 O O     . TRP B 1 238 ? 9.812   38.737 17.267 1.000 21.578  0 219 TRP B O     1 ? ? 
ATOM   3746 C CB    . TRP B 1 238 ? 7.270   37.787 16.135 1.000 22.520  0 219 TRP B CB    1 ? ? 
ATOM   3747 C CG    . TRP B 1 238 ? 7.288   36.433 16.771 1.000 22.951  0 219 TRP B CG    1 ? ? 
ATOM   3748 C CD1   . TRP B 1 238 ? 6.900   36.108 18.040 1.000 23.230  0 219 TRP B CD1   1 ? ? 
ATOM   3749 C CD2   . TRP B 1 238 ? 7.730   35.204 16.166 1.000 23.993  0 219 TRP B CD2   1 ? ? 
ATOM   3750 N NE1   . TRP B 1 238 ? 7.086   34.773 18.265 1.000 23.697  0 219 TRP B NE1   1 ? ? 
ATOM   3751 C CE2   . TRP B 1 238 ? 7.604   34.191 17.138 1.000 24.374  0 219 TRP B CE2   1 ? ? 
ATOM   3752 C CE3   . TRP B 1 238 ? 8.230   34.859 14.905 1.000 24.415  0 219 TRP B CE3   1 ? ? 
ATOM   3753 C CZ2   . TRP B 1 238 ? 7.955   32.863 16.888 1.000 25.026  0 219 TRP B CZ2   1 ? ? 
ATOM   3754 C CZ3   . TRP B 1 238 ? 8.555   33.544 14.648 1.000 24.027  0 219 TRP B CZ3   1 ? ? 
ATOM   3755 C CH2   . TRP B 1 238 ? 8.400   32.557 15.623 1.000 24.891  0 219 TRP B CH2   1 ? ? 
ATOM   3756 N N     . ILE B 1 239 ? 8.707   39.034 19.222 1.000 21.727  0 220 ILE B N     1 ? ? 
ATOM   3757 C CA    . ILE B 1 239 ? 9.893   39.050 20.075 1.000 20.961  0 220 ILE B CA    1 ? ? 
ATOM   3758 C C     . ILE B 1 239 ? 9.960   37.731 20.844 1.000 21.522  0 220 ILE B C     1 ? ? 
ATOM   3759 O O     . ILE B 1 239 ? 8.932   37.080 21.039 1.000 23.738  0 220 ILE B O     1 ? ? 
ATOM   3760 C CB    . ILE B 1 239 ? 9.905   40.303 20.993 1.000 20.856  0 220 ILE B CB    1 ? ? 
ATOM   3761 C CG1   . ILE B 1 239 ? 8.568   40.506 21.699 1.000 20.256  0 220 ILE B CG1   1 ? ? 
ATOM   3762 C CG2   . ILE B 1 239 ? 10.303  41.563 20.220 1.000 19.928  0 220 ILE B CG2   1 ? ? 
ATOM   3763 C CD1   . ILE B 1 239 ? 8.389   39.805 23.012 1.000 20.365  0 220 ILE B CD1   1 ? ? 
ATOM   3764 N N     . SER B 1 240 ? 11.165  37.337 21.273 1.000 20.426  0 221 SER B N     1 ? ? 
ATOM   3765 C CA    . SER B 1 240 ? 11.345  36.009 21.832 1.000 19.466  0 221 SER B CA    1 ? ? 
ATOM   3766 C C     . SER B 1 240 ? 10.853  35.921 23.276 1.000 20.050  0 221 SER B C     1 ? ? 
ATOM   3767 O O     . SER B 1 240 ? 10.323  34.888 23.679 1.000 20.368  0 221 SER B O     1 ? ? 
ATOM   3768 C CB    . SER B 1 240 ? 12.764  35.586 21.713 1.000 19.098  0 221 SER B CB    1 ? ? 
ATOM   3769 O OG    . SER B 1 240 ? 13.605  36.584 22.271 1.000 20.396  0 221 SER B OG    1 ? ? 
ATOM   3770 N N     . ASN B 1 241 ? 11.023  37.003 24.049 1.000 19.671  0 222 ASN B N     1 ? ? 
ATOM   3771 C CA    . ASN B 1 241 ? 10.861  36.972 25.492 1.000 19.276  0 222 ASN B CA    1 ? ? 
ATOM   3772 C C     . ASN B 1 241 ? 9.478   37.442 25.921 1.000 19.637  0 222 ASN B C     1 ? ? 
ATOM   3773 O O     . ASN B 1 241 ? 9.319   38.510 26.492 1.000 20.468  0 222 ASN B O     1 ? ? 
ATOM   3774 C CB    . ASN B 1 241 ? 11.967  37.784 26.160 1.000 19.868  0 222 ASN B CB    1 ? ? 
ATOM   3775 C CG    . ASN B 1 241 ? 13.345  37.313 25.744 1.000 20.173  0 222 ASN B CG    1 ? ? 
ATOM   3776 O OD1   . ASN B 1 241 ? 13.540  36.223 25.222 1.000 20.152  0 222 ASN B OD1   1 ? ? 
ATOM   3777 N ND2   . ASN B 1 241 ? 14.344  38.119 26.006 1.000 20.341  0 222 ASN B ND2   1 ? ? 
ATOM   3778 N N     . GLY B 1 242 ? 8.487   36.591 25.698 1.000 19.745  0 223 GLY B N     1 ? ? 
ATOM   3779 C CA    . GLY B 1 242 ? 7.117   36.901 26.056 1.000 20.302  0 223 GLY B CA    1 ? ? 
ATOM   3780 C C     . GLY B 1 242 ? 6.206   35.727 25.731 1.000 21.002  0 223 GLY B C     1 ? ? 
ATOM   3781 O O     . GLY B 1 242 ? 6.631   34.779 25.092 1.000 19.651  0 223 GLY B O     1 ? ? 
ATOM   3782 N N     . THR B 1 243 ? 4.982   35.789 26.259 1.000 23.170  0 224 THR B N     1 ? ? 
ATOM   3783 C CA    . THR B 1 243 ? 3.925   34.828 25.996 1.000 23.821  0 224 THR B CA    1 ? ? 
ATOM   3784 C C     . THR B 1 243 ? 2.635   35.627 25.849 1.000 24.680  0 224 THR B C     1 ? ? 
ATOM   3785 O O     . THR B 1 243 ? 2.578   36.817 26.160 1.000 23.458  0 224 THR B O     1 ? ? 
ATOM   3786 C CB    . THR B 1 243 ? 3.789   33.776 27.113 1.000 24.305  0 224 THR B CB    1 ? ? 
ATOM   3787 O OG1   . THR B 1 243 ? 3.628   34.453 28.360 1.000 26.069  0 224 THR B OG1   1 ? ? 
ATOM   3788 C CG2   . THR B 1 243 ? 4.939   32.798 27.210 1.000 23.462  0 224 THR B CG2   1 ? ? 
ATOM   3789 N N     . GLY B 1 244 ? 1.602   34.977 25.332 1.000 26.324  0 225 GLY B N     1 ? ? 
ATOM   3790 C CA    . GLY B 1 244 ? 0.299   35.610 25.347 1.000 29.606  0 225 GLY B CA    1 ? ? 
ATOM   3791 C C     . GLY B 1 244 ? -0.509  35.296 24.095 1.000 29.769  0 225 GLY B C     1 ? ? 
ATOM   3792 O O     . GLY B 1 244 ? -0.107  34.492 23.248 1.000 30.944  0 225 GLY B O     1 ? ? 
ATOM   3793 N N     . ASN B 1 245 ? -1.669  35.947 24.002 1.000 29.573  0 226 ASN B N     1 ? ? 
ATOM   3794 C CA    . ASN B 1 245 ? -2.599  35.612 22.944 1.000 28.820  0 226 ASN B CA    1 ? ? 
ATOM   3795 C C     . ASN B 1 245 ? -2.340  36.527 21.760 1.000 27.016  0 226 ASN B C     1 ? ? 
ATOM   3796 O O     . ASN B 1 245 ? -2.532  37.734 21.886 1.000 26.269  0 226 ASN B O     1 ? ? 
ATOM   3797 C CB    . ASN B 1 245 ? -4.052  35.728 23.409 1.000 29.992  0 226 ASN B CB    1 ? ? 
ATOM   3798 C CG    . ASN B 1 245 ? -5.021  35.213 22.366 1.000 31.905  0 226 ASN B CG    1 ? ? 
ATOM   3799 O OD1   . ASN B 1 245 ? -5.300  35.901 21.388 1.000 32.789  0 226 ASN B OD1   1 ? ? 
ATOM   3800 N ND2   . ASN B 1 245 ? -5.503  33.992 22.542 1.000 30.980  0 226 ASN B ND2   1 ? ? 
ATOM   3801 N N     . ILE B 1 246 ? -1.979  35.945 20.605 1.000 25.866  0 227 ILE B N     1 ? ? 
ATOM   3802 C CA    . ILE B 1 246 ? -1.616  36.756 19.448 1.000 24.539  0 227 ILE B CA    1 ? ? 
ATOM   3803 C C     . ILE B 1 246 ? -2.836  37.500 18.912 1.000 23.554  0 227 ILE B C     1 ? ? 
ATOM   3804 O O     . ILE B 1 246 ? -2.755  38.697 18.668 1.000 22.727  0 227 ILE B O     1 ? ? 
ATOM   3805 C CB    . ILE B 1 246 ? -0.883  35.931 18.375 1.000 24.783  0 227 ILE B CB    1 ? ? 
ATOM   3806 C CG1   . ILE B 1 246 ? 0.504   35.535 18.880 1.000 25.192  0 227 ILE B CG1   1 ? ? 
ATOM   3807 C CG2   . ILE B 1 246 ? -0.785  36.665 17.045 1.000 25.563  0 227 ILE B CG2   1 ? ? 
ATOM   3808 C CD1   . ILE B 1 246 ? 1.200   34.514 18.042 1.000 24.687  0 227 ILE B CD1   1 ? ? 
ATOM   3809 N N     . VAL B 1 247 ? -3.964  36.800 18.734 1.000 23.152  0 228 VAL B N     1 ? ? 
ATOM   3810 C CA    . VAL B 1 247 ? -5.187  37.438 18.258 1.000 23.077  0 228 VAL B CA    1 ? ? 
ATOM   3811 C C     . VAL B 1 247 ? -5.553  38.635 19.145 1.000 23.228  0 228 VAL B C     1 ? ? 
ATOM   3812 O O     . VAL B 1 247 ? -5.914  39.699 18.650 1.000 24.674  0 228 VAL B O     1 ? ? 
ATOM   3813 C CB    . VAL B 1 247 ? -6.360  36.440 18.132 1.000 22.611  0 228 VAL B CB    1 ? ? 
ATOM   3814 C CG1   . VAL B 1 247 ? -7.687  37.123 17.866 1.000 24.382  0 228 VAL B CG1   1 ? ? 
ATOM   3815 C CG2   . VAL B 1 247 ? -6.137  35.399 17.067 1.000 22.677  0 228 VAL B CG2   1 ? ? 
ATOM   3816 N N     . SER B 1 248 ? -5.501  38.458 20.463 1.000 23.679  0 229 SER B N     1 ? ? 
ATOM   3817 C CA    . SER B 1 248 ? -5.928  39.493 21.387 1.000 23.402  0 229 SER B CA    1 ? ? 
ATOM   3818 C C     . SER B 1 248 ? -5.063  40.745 21.238 1.000 23.531  0 229 SER B C     1 ? ? 
ATOM   3819 O O     . SER B 1 248 ? -5.614  41.844 21.220 1.000 23.985  0 229 SER B O     1 ? ? 
ATOM   3820 C CB    . SER B 1 248 ? -5.954  38.884 22.773 1.000 23.703  0 229 SER B CB    1 ? ? 
ATOM   3821 O OG    . SER B 1 248 ? -5.704  39.796 23.796 1.000 26.383  0 229 SER B OG    1 ? ? 
ATOM   3822 N N     . SER B 1 249 ? -3.729  40.561 21.117 1.000 22.505  0 230 SER B N     1 ? ? 
ATOM   3823 C CA    . SER B 1 249 ? -2.769  41.650 21.020 1.000 21.437  0 230 SER B CA    1 ? ? 
ATOM   3824 C C     . SER B 1 249 ? -2.948  42.392 19.695 1.000 21.088  0 230 SER B C     1 ? ? 
ATOM   3825 O O     . SER B 1 249 ? -2.880  43.628 19.649 1.000 20.565  0 230 SER B O     1 ? ? 
ATOM   3826 C CB    . SER B 1 249 ? -1.339  41.164 21.212 1.000 21.395  0 230 SER B CB    1 ? ? 
ATOM   3827 O OG    . SER B 1 249 ? -0.880  40.348 20.133 1.000 21.439  0 230 SER B OG    1 ? ? 
ATOM   3828 N N     . VAL B 1 250 ? -3.248  41.633 18.629 1.000 20.718  0 231 VAL B N     1 ? ? 
ATOM   3829 C CA    . VAL B 1 250 ? -3.411  42.205 17.304 1.000 21.398  0 231 VAL B CA    1 ? ? 
ATOM   3830 C C     . VAL B 1 250 ? -4.671  43.073 17.300 1.000 22.101  0 231 VAL B C     1 ? ? 
ATOM   3831 O O     . VAL B 1 250 ? -4.675  44.192 16.784 1.000 20.944  0 231 VAL B O     1 ? ? 
ATOM   3832 C CB    . VAL B 1 250 ? -3.417  41.124 16.200 1.000 22.273  0 231 VAL B CB    1 ? ? 
ATOM   3833 C CG1   . VAL B 1 250 ? -3.812  41.688 14.846 1.000 22.703  0 231 VAL B CG1   1 ? ? 
ATOM   3834 C CG2   . VAL B 1 250 ? -2.085  40.389 16.096 1.000 22.107  0 231 VAL B CG2   1 ? ? 
ATOM   3835 N N     . ASN B 1 251 ? -5.748  42.581 17.907 1.000 23.678  0 232 ASN B N     1 ? ? 
ATOM   3836 C CA    . ASN B 1 251 ? -6.974  43.360 17.947 1.000 25.380  0 232 ASN B CA    1 ? ? 
ATOM   3837 C C     . ASN B 1 251 ? -6.816  44.621 18.804 1.000 26.696  0 232 ASN B C     1 ? ? 
ATOM   3838 O O     . ASN B 1 251 ? -7.479  45.628 18.564 1.000 28.142  0 232 ASN B O     1 ? ? 
ATOM   3839 C CB    . ASN B 1 251 ? -8.144  42.521 18.449 1.000 25.944  0 232 ASN B CB    1 ? ? 
ATOM   3840 C CG    . ASN B 1 251 ? -8.600  41.499 17.436 1.000 26.986  0 232 ASN B CG    1 ? ? 
ATOM   3841 O OD1   . ASN B 1 251 ? -8.829  41.834 16.283 1.000 26.132  0 232 ASN B OD1   1 ? ? 
ATOM   3842 N ND2   . ASN B 1 251 ? -8.728  40.249 17.852 1.000 29.062  0 232 ASN B ND2   1 ? ? 
ATOM   3843 N N     . MET B 1 252 ? -5.953  44.576 19.817 1.000 26.896  0 233 MET B N     1 ? ? 
ATOM   3844 C CA    . MET B 1 252 ? -5.767  45.734 20.671 1.000 28.291  0 233 MET B CA    1 ? ? 
ATOM   3845 C C     . MET B 1 252 ? -5.125  46.871 19.884 1.000 26.323  0 233 MET B C     1 ? ? 
ATOM   3846 O O     . MET B 1 252 ? -5.499  48.035 20.012 1.000 23.979  0 233 MET B O     1 ? ? 
ATOM   3847 C CB    . MET B 1 252 ? -4.831  45.372 21.817 1.000 32.545  0 233 MET B CB    1 ? ? 
ATOM   3848 C CG    . MET B 1 252 ? -5.099  46.197 23.000 1.000 37.918  0 233 MET B CG    1 ? ? 
ATOM   3849 S SD    . MET B 1 252 ? -5.898  45.204 24.257 1.000 48.006  0 233 MET B SD    1 ? ? 
ATOM   3850 C CE    . MET B 1 252 ? -4.554  44.047 24.516 1.000 44.287  0 233 MET B CE    1 ? ? 
ATOM   3851 N N     . VAL B 1 253 ? -4.150  46.521 19.051 1.000 24.375  0 234 VAL B N     1 ? ? 
ATOM   3852 C CA    . VAL B 1 253 ? -3.537  47.499 18.172 1.000 23.384  0 234 VAL B CA    1 ? ? 
ATOM   3853 C C     . VAL B 1 253 ? -4.565  48.011 17.163 1.000 23.188  0 234 VAL B C     1 ? ? 
ATOM   3854 O O     . VAL B 1 253 ? -4.635  49.213 16.927 1.000 21.544  0 234 VAL B O     1 ? ? 
ATOM   3855 C CB    . VAL B 1 253 ? -2.300  46.898 17.494 1.000 22.501  0 234 VAL B CB    1 ? ? 
ATOM   3856 C CG1   . VAL B 1 253 ? -1.778  47.792 16.371 1.000 21.184  0 234 VAL B CG1   1 ? ? 
ATOM   3857 C CG2   . VAL B 1 253 ? -1.229  46.579 18.531 1.000 21.573  0 234 VAL B CG2   1 ? ? 
ATOM   3858 N N     . SER B 1 254 ? -5.366  47.108 16.581 1.000 21.978  0 235 SER B N     1 ? ? 
ATOM   3859 C CA    . SER B 1 254 ? -6.372  47.542 15.629 1.000 23.938  0 235 SER B CA    1 ? ? 
ATOM   3860 C C     . SER B 1 254 ? -7.310  48.554 16.282 1.000 25.942  0 235 SER B C     1 ? ? 
ATOM   3861 O O     . SER B 1 254 ? -7.721  49.516 15.640 1.000 27.454  0 235 SER B O     1 ? ? 
ATOM   3862 C CB    . SER B 1 254 ? -7.127  46.383 15.077 1.000 23.682  0 235 SER B CB    1 ? ? 
ATOM   3863 O OG    . SER B 1 254 ? -6.257  45.442 14.458 1.000 24.329  0 235 SER B OG    1 ? ? 
ATOM   3864 N N     . ARG B 1 255 ? -7.649  48.321 17.553 1.000 26.927  0 236 ARG B N     1 ? ? 
ATOM   3865 C CA    . ARG B 1 255 ? -8.569  49.201 18.254 1.000 27.752  0 236 ARG B CA    1 ? ? 
ATOM   3866 C C     . ARG B 1 255 ? -7.914  50.563 18.499 1.000 26.974  0 236 ARG B C     1 ? ? 
ATOM   3867 O O     . ARG B 1 255 ? -8.548  51.604 18.330 1.000 25.443  0 236 ARG B O     1 ? ? 
ATOM   3868 C CB    . ARG B 1 255 ? -9.072  48.557 19.550 1.000 30.093  0 236 ARG B CB    1 ? ? 
ATOM   3869 C CG    . ARG B 1 255 ? -10.183 47.542 19.348 1.000 32.735  0 236 ARG B CG    1 ? ? 
ATOM   3870 C CD    . ARG B 1 255 ? -10.640 46.901 20.660 1.000 38.464  0 236 ARG B CD    1 ? ? 
ATOM   3871 N NE    . ARG B 1 255 ? -10.926 45.461 20.541 1.000 44.049  0 236 ARG B NE    1 ? ? 
ATOM   3872 C CZ    . ARG B 1 255 ? -10.230 44.414 21.038 1.000 44.058  0 236 ARG B CZ    1 ? ? 
ATOM   3873 N NH1   . ARG B 1 255 ? -9.105  44.556 21.733 1.000 43.895  0 236 ARG B NH1   1 ? ? 
ATOM   3874 N NH2   . ARG B 1 255 ? -10.706 43.194 20.847 1.000 44.525  0 236 ARG B NH2   1 ? ? 
ATOM   3875 N N     . LEU B 1 256 ? -6.642  50.542 18.915 1.000 27.238  0 237 LEU B N     1 ? ? 
ATOM   3876 C CA    . LEU B 1 256 ? -5.839  51.735 19.163 1.000 25.574  0 237 LEU B CA    1 ? ? 
ATOM   3877 C C     . LEU B 1 256 ? -5.733  52.580 17.894 1.000 25.567  0 237 LEU B C     1 ? ? 
ATOM   3878 O O     . LEU B 1 256 ? -5.789  53.811 17.942 1.000 24.808  0 237 LEU B O     1 ? ? 
ATOM   3879 C CB    . LEU B 1 256 ? -4.441  51.301 19.615 1.000 25.300  0 237 LEU B CB    1 ? ? 
ATOM   3880 C CG    . LEU B 1 256 ? -3.437  52.418 19.881 1.000 26.832  0 237 LEU B CG    1 ? ? 
ATOM   3881 C CD1   . LEU B 1 256 ? -3.657  52.949 21.278 1.000 28.277  0 237 LEU B CD1   1 ? ? 
ATOM   3882 C CD2   . LEU B 1 256 ? -1.999  51.930 19.747 1.000 27.603  0 237 LEU B CD2   1 ? ? 
ATOM   3883 N N     . LEU B 1 257 ? -5.488  51.924 16.756 1.000 24.629  0 238 LEU B N     1 ? ? 
ATOM   3884 C CA    . LEU B 1 257 ? -5.292  52.663 15.515 1.000 22.865  0 238 LEU B CA    1 ? ? 
ATOM   3885 C C     . LEU B 1 257 ? -6.619  53.199 14.987 1.000 24.977  0 238 LEU B C     1 ? ? 
ATOM   3886 O O     . LEU B 1 257 ? -6.677  54.327 14.501 1.000 27.229  0 238 LEU B O     1 ? ? 
ATOM   3887 C CB    . LEU B 1 257 ? -4.578  51.787 14.485 1.000 20.543  0 238 LEU B CB    1 ? ? 
ATOM   3888 C CG    . LEU B 1 257 ? -3.159  51.375 14.859 1.000 18.694  0 238 LEU B CG    1 ? ? 
ATOM   3889 C CD1   . LEU B 1 257 ? -2.553  50.512 13.757 1.000 18.682  0 238 LEU B CD1   1 ? ? 
ATOM   3890 C CD2   . LEU B 1 257 ? -2.286  52.591 15.145 1.000 18.238  0 238 LEU B CD2   1 ? ? 
ATOM   3891 N N     . LEU B 1 258 ? -7.695  52.419 15.110 1.000 28.036  0 239 LEU B N     1 ? ? 
ATOM   3892 C CA    . LEU B 1 258 ? -9.002  52.895 14.699 1.000 28.387  0 239 LEU B CA    1 ? ? 
ATOM   3893 C C     . LEU B 1 258 ? -9.423  54.120 15.507 1.000 31.183  0 239 LEU B C     1 ? ? 
ATOM   3894 O O     . LEU B 1 258 ? -9.895  55.102 14.935 1.000 32.081  0 239 LEU B O     1 ? ? 
ATOM   3895 C CB    . LEU B 1 258 ? -9.996  51.750 14.854 1.000 28.658  0 239 LEU B CB    1 ? ? 
ATOM   3896 C CG    . LEU B 1 258 ? -9.961  50.757 13.697 1.000 30.516  0 239 LEU B CG    1 ? ? 
ATOM   3897 C CD1   . LEU B 1 258 ? -10.676 49.467 14.060 1.000 31.043  0 239 LEU B CD1   1 ? ? 
ATOM   3898 C CD2   . LEU B 1 258 ? -10.507 51.372 12.429 1.000 32.050  0 239 LEU B CD2   1 ? ? 
ATOM   3899 N N     . ASN B 1 259 ? -9.232  54.060 16.830 1.000 34.329  0 240 ASN B N     1 ? ? 
ATOM   3900 C CA    . ASN B 1 259 ? -9.584  55.162 17.713 1.000 35.319  0 240 ASN B CA    1 ? ? 
ATOM   3901 C C     . ASN B 1 259 ? -8.772  56.412 17.357 1.000 34.757  0 240 ASN B C     1 ? ? 
ATOM   3902 O O     . ASN B 1 259 ? -9.228  57.528 17.543 1.000 32.960  0 240 ASN B O     1 ? ? 
ATOM   3903 C CB    . ASN B 1 259 ? -9.419  54.782 19.185 1.000 38.922  0 240 ASN B CB    1 ? ? 
ATOM   3904 C CG    . ASN B 1 259 ? -9.758  55.928 20.119 1.000 43.035  0 240 ASN B CG    1 ? ? 
ATOM   3905 O OD1   . ASN B 1 259 ? -10.919 56.291 20.269 1.000 44.884  0 240 ASN B OD1   1 ? ? 
ATOM   3906 N ND2   . ASN B 1 259 ? -8.748  56.526 20.726 1.000 41.215  0 240 ASN B ND2   1 ? ? 
ATOM   3907 N N     . ARG B 1 260 ? -7.558  56.232 16.854 1.000 36.027  0 241 ARG B N     1 ? ? 
ATOM   3908 C CA    . ARG B 1 260 ? -6.712  57.374 16.598 1.000 36.146  0 241 ARG B CA    1 ? ? 
ATOM   3909 C C     . ARG B 1 260 ? -7.120  58.121 15.340 1.000 39.275  0 241 ARG B C     1 ? ? 
ATOM   3910 O O     . ARG B 1 260 ? -6.587  59.207 15.140 1.000 42.581  0 241 ARG B O     1 ? ? 
ATOM   3911 C CB    . ARG B 1 260 ? -5.239  56.970 16.523 1.000 33.136  0 241 ARG B CB    1 ? ? 
ATOM   3912 C CG    . ARG B 1 260 ? -4.642  56.582 17.865 1.000 32.823  0 241 ARG B CG    1 ? ? 
ATOM   3913 C CD    . ARG B 1 260 ? -3.140  56.468 17.848 1.000 30.841  0 241 ARG B CD    1 ? ? 
ATOM   3914 N NE    . ARG B 1 260 ? -2.528  56.352 19.168 1.000 29.496  0 241 ARG B NE    1 ? ? 
ATOM   3915 C CZ    . ARG B 1 260 ? -1.219  56.136 19.384 1.000 29.123  0 241 ARG B CZ    1 ? ? 
ATOM   3916 N NH1   . ARG B 1 260 ? -0.731  56.071 20.599 1.000 26.475  0 241 ARG B NH1   1 ? ? 
ATOM   3917 N NH2   . ARG B 1 260 ? -0.357  56.039 18.385 1.000 27.114  0 241 ARG B NH2   1 ? ? 
ATOM   3918 N N     . PHE B 1 261 ? -8.078  57.594 14.556 1.000 38.623  0 242 PHE B N     1 ? ? 
ATOM   3919 C CA    . PHE B 1 261 ? -8.642  58.347 13.440 1.000 36.953  0 242 PHE B CA    1 ? ? 
ATOM   3920 C C     . PHE B 1 261 ? -9.481  59.507 13.978 1.000 39.340  0 242 PHE B C     1 ? ? 
ATOM   3921 O O     . PHE B 1 261 ? -9.464  60.615 13.448 1.000 40.229  0 242 PHE B O     1 ? ? 
ATOM   3922 C CB    . PHE B 1 261 ? -9.558  57.461 12.586 1.000 33.548  0 242 PHE B CB    1 ? ? 
ATOM   3923 C CG    . PHE B 1 261 ? -8.834  56.534 11.644 1.000 32.043  0 242 PHE B CG    1 ? ? 
ATOM   3924 C CD1   . PHE B 1 261 ? -7.933  57.035 10.722 1.000 31.954  0 242 PHE B CD1   1 ? ? 
ATOM   3925 C CD2   . PHE B 1 261 ? -9.034  55.160 11.687 1.000 32.775  0 242 PHE B CD2   1 ? ? 
ATOM   3926 C CE1   . PHE B 1 261 ? -7.245  56.190 9.869  1.000 31.899  0 242 PHE B CE1   1 ? ? 
ATOM   3927 C CE2   . PHE B 1 261 ? -8.339  54.316 10.832 1.000 33.706  0 242 PHE B CE2   1 ? ? 
ATOM   3928 C CZ    . PHE B 1 261 ? -7.449  54.836 9.922  1.000 33.693  0 242 PHE B CZ    1 ? ? 
ATOM   3929 N N     . THR B 1 262 ? -10.199 59.250 15.073 1.000 42.594  0 243 THR B N     1 ? ? 
ATOM   3930 C CA    . THR B 1 262 ? -11.201 60.204 15.526 1.000 44.691  0 243 THR B CA    1 ? ? 
ATOM   3931 C C     . THR B 1 262 ? -10.583 61.186 16.524 1.000 49.667  0 243 THR B C     1 ? ? 
ATOM   3932 O O     . THR B 1 262 ? -10.570 62.427 16.363 1.000 52.246  0 243 THR B O     1 ? ? 
ATOM   3933 C CB    . THR B 1 262 ? -12.453 59.443 15.987 1.000 44.644  0 243 THR B CB    1 ? ? 
ATOM   3934 O OG1   . THR B 1 262 ? -12.214 58.658 17.157 1.000 43.564  0 243 THR B OG1   1 ? ? 
ATOM   3935 C CG2   . THR B 1 262 ? -13.074 58.628 14.869 1.000 41.798  0 243 THR B CG2   1 ? ? 
ATOM   3936 N N     . MET B 1 263 ? -9.986  60.592 17.549 1.000 54.994  0 244 MET B N     1 ? ? 
ATOM   3937 C CA    . MET B 1 263 ? -9.424  61.343 18.658 1.000 58.421  0 244 MET B CA    1 ? ? 
ATOM   3938 C C     . MET B 1 263 ? -8.461  62.402 18.146 1.000 65.518  0 244 MET B C     1 ? ? 
ATOM   3939 O O     . MET B 1 263 ? -7.485  62.062 17.487 1.000 68.694  0 244 MET B O     1 ? ? 
ATOM   3940 C CB    . MET B 1 263 ? -8.633  60.375 19.517 1.000 61.391  0 244 MET B CB    1 ? ? 
ATOM   3941 C CG    . MET B 1 263 ? -7.203  60.758 19.658 1.000 69.644  0 244 MET B CG    1 ? ? 
ATOM   3942 S SD    . MET B 1 263 ? -5.793  59.701 19.655 1.000 76.238  0 244 MET B SD    1 ? ? 
ATOM   3943 C CE    . MET B 1 263 ? -6.082  58.334 20.778 1.000 80.113  0 244 MET B CE    1 ? ? 
ATOM   3944 N N     . THR B 1 264 ? -8.792  63.671 18.372 1.000 68.616  0 245 THR B N     1 ? ? 
ATOM   3945 C CA    . THR B 1 264 ? -8.186  64.667 17.518 1.000 66.881  0 245 THR B CA    1 ? ? 
ATOM   3946 C C     . THR B 1 264 ? -6.682  64.740 17.756 1.000 58.919  0 245 THR B C     1 ? ? 
ATOM   3947 O O     . THR B 1 264 ? -6.164  64.359 18.813 1.000 50.110  0 245 THR B O     1 ? ? 
ATOM   3948 C CB    . THR B 1 264 ? -9.027  65.942 17.418 1.000 75.203  0 245 THR B CB    1 ? ? 
ATOM   3949 O OG1   . THR B 1 264 ? -9.901  65.748 16.302 1.000 77.578  0 245 THR B OG1   1 ? ? 
ATOM   3950 C CG2   . THR B 1 264 ? -8.186  67.185 17.194 1.000 72.782  0 245 THR B CG2   1 ? ? 
ATOM   3951 N N     . HIS B 1 265 ? -6.027  65.216 16.689 1.000 57.250  0 246 HIS B N     1 ? ? 
ATOM   3952 C CA    . HIS B 1 265 ? -4.592  65.112 16.539 1.000 56.579  0 246 HIS B CA    1 ? ? 
ATOM   3953 C C     . HIS B 1 265 ? -3.919  65.489 17.851 1.000 54.824  0 246 HIS B C     1 ? ? 
ATOM   3954 O O     . HIS B 1 265 ? -4.238  66.510 18.458 1.000 51.749  0 246 HIS B O     1 ? ? 
ATOM   3955 C CB    . HIS B 1 265 ? -4.086  65.924 15.341 1.000 54.270  0 246 HIS B CB    1 ? ? 
ATOM   3956 C CG    . HIS B 1 265 ? -2.626  65.757 15.081 1.000 56.945  0 246 HIS B CG    1 ? ? 
ATOM   3957 N ND1   . HIS B 1 265 ? -2.156  64.798 14.235 1.000 59.641  0 246 HIS B ND1   1 ? ? 
ATOM   3958 C CD2   . HIS B 1 265 ? -1.540  66.447 15.493 1.000 59.446  0 246 HIS B CD2   1 ? ? 
ATOM   3959 C CE1   . HIS B 1 265 ? -0.854  64.901 14.128 1.000 61.555  0 246 HIS B CE1   1 ? ? 
ATOM   3960 N NE2   . HIS B 1 265 ? -0.434  65.866 14.927 1.000 59.698  0 246 HIS B NE2   1 ? ? 
ATOM   3961 N N     . ARG B 1 266 ? -3.009  64.608 18.256 1.000 51.923  0 247 ARG B N     1 ? ? 
ATOM   3962 C CA    . ARG B 1 266 ? -2.027  64.932 19.258 1.000 44.905  0 247 ARG B CA    1 ? ? 
ATOM   3963 C C     . ARG B 1 266 ? -0.666  64.903 18.600 1.000 41.767  0 247 ARG B C     1 ? ? 
ATOM   3964 O O     . ARG B 1 266 ? -0.348  63.935 17.918 1.000 44.110  0 247 ARG B O     1 ? ? 
ATOM   3965 C CB    . ARG B 1 266 ? -2.068  63.916 20.387 1.000 42.539  0 247 ARG B CB    1 ? ? 
ATOM   3966 C CG    . ARG B 1 266 ? -2.428  64.615 21.678 1.000 39.743  0 247 ARG B CG    1 ? ? 
ATOM   3967 C CD    . ARG B 1 266 ? -2.848  63.699 22.801 1.000 39.231  0 247 ARG B CD    1 ? ? 
ATOM   3968 N NE    . ARG B 1 266 ? -2.553  62.270 22.728 1.000 40.470  0 247 ARG B NE    1 ? ? 
ATOM   3969 C CZ    . ARG B 1 266 ? -3.478  61.325 22.594 1.000 40.716  0 247 ARG B CZ    1 ? ? 
ATOM   3970 N NH1   . ARG B 1 266 ? -4.756  61.673 22.466 1.000 39.503  0 247 ARG B NH1   1 ? ? 
ATOM   3971 N NH2   . ARG B 1 266 ? -3.110  60.053 22.552 1.000 42.567  0 247 ARG B NH2   1 ? ? 
ATOM   3972 N N     . ARG B 1 267 ? 0.100   65.988 18.753 1.000 39.017  0 248 ARG B N     1 ? ? 
ATOM   3973 C CA    . ARG B 1 267 ? 1.411   65.996 18.129 1.000 37.204  0 248 ARG B CA    1 ? ? 
ATOM   3974 C C     . ARG B 1 267 ? 2.296   64.941 18.786 1.000 32.952  0 248 ARG B C     1 ? ? 
ATOM   3975 O O     . ARG B 1 267 ? 2.171   64.640 19.969 1.000 31.999  0 248 ARG B O     1 ? ? 
ATOM   3976 C CB    . ARG B 1 267 ? 1.998   67.401 18.071 1.000 39.360  0 248 ARG B CB    1 ? ? 
ATOM   3977 C CG    . ARG B 1 267 ? 1.162   68.353 17.224 1.000 45.830  0 248 ARG B CG    1 ? ? 
ATOM   3978 C CD    . ARG B 1 267 ? 1.740   69.686 16.782 1.000 53.014  0 248 ARG B CD    1 ? ? 
ATOM   3979 N NE    . ARG B 1 267 ? 2.539   70.289 17.829 1.000 62.182  0 248 ARG B NE    1 ? ? 
ATOM   3980 C CZ    . ARG B 1 267 ? 3.561   71.118 17.617 1.000 62.595  0 248 ARG B CZ    1 ? ? 
ATOM   3981 N NH1   . ARG B 1 267 ? 3.906   71.456 16.384 1.000 64.827  0 248 ARG B NH1   1 ? ? 
ATOM   3982 N NH2   . ARG B 1 267 ? 4.241   71.604 18.642 1.000 56.606  0 248 ARG B NH2   1 ? ? 
ATOM   3983 N N     . PRO B 1 268 ? 3.202   64.296 18.023 1.000 29.536  0 249 PRO B N     1 ? ? 
ATOM   3984 C CA    . PRO B 1 268 ? 4.001   63.204 18.568 1.000 26.515  0 249 PRO B CA    1 ? ? 
ATOM   3985 C C     . PRO B 1 268 ? 4.866   63.672 19.727 1.000 23.926  0 249 PRO B C     1 ? ? 
ATOM   3986 O O     . PRO B 1 268 ? 5.303   64.816 19.751 1.000 21.446  0 249 PRO B O     1 ? ? 
ATOM   3987 C CB    . PRO B 1 268 ? 4.842   62.718 17.383 1.000 25.659  0 249 PRO B CB    1 ? ? 
ATOM   3988 C CG    . PRO B 1 268 ? 4.802   63.859 16.411 1.000 26.266  0 249 PRO B CG    1 ? ? 
ATOM   3989 C CD    . PRO B 1 268 ? 3.447   64.504 16.590 1.000 28.005  0 249 PRO B CD    1 ? ? 
ATOM   3990 N N     . THR B 1 269 ? 5.036   62.777 20.703 1.000 23.502  0 250 THR B N     1 ? ? 
ATOM   3991 C CA    . THR B 1 269 ? 5.922   62.986 21.831 1.000 23.764  0 250 THR B CA    1 ? ? 
ATOM   3992 C C     . THR B 1 269 ? 7.348   62.828 21.321 1.000 25.637  0 250 THR B C     1 ? ? 
ATOM   3993 O O     . THR B 1 269 ? 7.739   61.737 20.907 1.000 27.028  0 250 THR B O     1 ? ? 
ATOM   3994 C CB    . THR B 1 269 ? 5.639   61.936 22.905 1.000 23.241  0 250 THR B CB    1 ? ? 
ATOM   3995 O OG1   . THR B 1 269 ? 4.231   61.940 23.136 1.000 23.664  0 250 THR B OG1   1 ? ? 
ATOM   3996 C CG2   . THR B 1 269 ? 6.411   62.196 24.176 1.000 21.833  0 250 THR B CG2   1 ? ? 
ATOM   3997 N N     . ILE B 1 270 ? 8.097   63.935 21.297 1.000 25.423  0 251 ILE B N     1 ? ? 
ATOM   3998 C CA    . ILE B 1 270 ? 9.437   63.942 20.752 1.000 25.254  0 251 ILE B CA    1 ? ? 
ATOM   3999 C C     . ILE B 1 270 ? 10.415  63.560 21.854 1.000 27.755  0 251 ILE B C     1 ? ? 
ATOM   4000 O O     . ILE B 1 270 ? 10.342  64.103 22.951 1.000 29.385  0 251 ILE B O     1 ? ? 
ATOM   4001 C CB    . ILE B 1 270 ? 9.738   65.330 20.164 1.000 24.714  0 251 ILE B CB    1 ? ? 
ATOM   4002 C CG1   . ILE B 1 270 ? 8.770   65.677 19.034 1.000 24.022  0 251 ILE B CG1   1 ? ? 
ATOM   4003 C CG2   . ILE B 1 270 ? 11.190  65.445 19.718 1.000 26.621  0 251 ILE B CG2   1 ? ? 
ATOM   4004 C CD1   . ILE B 1 270 ? 9.128   65.054 17.705 1.000 23.761  0 251 ILE B CD1   1 ? ? 
ATOM   4005 N N     . GLU B 1 271 ? 11.328  62.633 21.554 1.000 29.857  0 252 GLU B N     1 ? ? 
ATOM   4006 C CA    . GLU B 1 271 ? 12.402  62.312 22.483 1.000 31.277  0 252 GLU B CA    1 ? ? 
ATOM   4007 C C     . GLU B 1 271 ? 13.774  62.566 21.874 1.000 31.561  0 252 GLU B C     1 ? ? 
ATOM   4008 O O     . GLU B 1 271 ? 13.904  62.901 20.699 1.000 30.077  0 252 GLU B O     1 ? ? 
ATOM   4009 C CB    . GLU B 1 271 ? 12.211  60.888 22.969 1.000 33.208  0 252 GLU B CB    1 ? ? 
ATOM   4010 C CG    . GLU B 1 271 ? 10.788  60.796 23.412 1.000 38.507  0 252 GLU B CG    1 ? ? 
ATOM   4011 C CD    . GLU B 1 271 ? 10.393  59.562 24.121 1.000 42.099  0 252 GLU B CD    1 ? ? 
ATOM   4012 O OE1   . GLU B 1 271 ? 11.024  58.541 23.837 1.000 40.821  0 252 GLU B OE1   1 ? ? 
ATOM   4013 O OE2   . GLU B 1 271 ? 9.424   59.644 24.885 1.000 46.601  0 252 GLU B OE2   1 ? ? 
ATOM   4014 N N     . LYS B 1 272 ? 14.787  62.428 22.731 1.000 30.911  0 253 LYS B N     1 ? ? 
ATOM   4015 C CA    . LYS B 1 272 ? 16.164  62.489 22.291 1.000 29.973  0 253 LYS B CA    1 ? ? 
ATOM   4016 C C     . LYS B 1 272 ? 16.543  61.184 21.598 1.000 28.131  0 253 LYS B C     1 ? ? 
ATOM   4017 O O     . LYS B 1 272 ? 16.292  60.074 22.095 1.000 27.550  0 253 LYS B O     1 ? ? 
ATOM   4018 C CB    . LYS B 1 272 ? 17.125  62.780 23.447 1.000 30.221  0 253 LYS B CB    1 ? ? 
ATOM   4019 C CG    . LYS B 1 272 ? 18.352  63.566 23.021 1.000 32.259  0 253 LYS B CG    1 ? ? 
ATOM   4020 C CD    . LYS B 1 272 ? 19.232  63.946 24.172 1.000 33.577  0 253 LYS B CD    1 ? ? 
ATOM   4021 C CE    . LYS B 1 272 ? 20.705  63.962 23.810 1.000 34.385  0 253 LYS B CE    1 ? ? 
ATOM   4022 N NZ    . LYS B 1 272 ? 21.281  62.595 23.783 1.000 33.989  0 253 LYS B NZ    1 ? ? 
ATOM   4023 N N     . ASP B 1 273 ? 17.217  61.359 20.457 1.000 24.727  0 254 ASP B N     1 ? ? 
ATOM   4024 C CA    . ASP B 1 273 ? 17.739  60.245 19.694 1.000 23.956  0 254 ASP B CA    1 ? ? 
ATOM   4025 C C     . ASP B 1 273 ? 18.878  59.590 20.474 1.000 24.885  0 254 ASP B C     1 ? ? 
ATOM   4026 O O     . ASP B 1 273 ? 19.433  60.190 21.392 1.000 25.457  0 254 ASP B O     1 ? ? 
ATOM   4027 C CB    . ASP B 1 273 ? 18.121  60.686 18.283 1.000 21.634  0 254 ASP B CB    1 ? ? 
ATOM   4028 C CG    . ASP B 1 273 ? 18.268  59.531 17.320 1.000 21.220  0 254 ASP B CG    1 ? ? 
ATOM   4029 O OD1   . ASP B 1 273 ? 17.810  58.430 17.631 1.000 22.729  0 254 ASP B OD1   1 ? ? 
ATOM   4030 O OD2   . ASP B 1 273 ? 18.787  59.752 16.234 1.000 19.336  0 254 ASP B OD2   1 ? ? 
ATOM   4031 N N     . VAL B 1 274 ? 19.206  58.350 20.104 1.000 23.529  0 255 VAL B N     1 ? ? 
ATOM   4032 C CA    . VAL B 1 274 ? 20.241  57.564 20.749 1.000 22.859  0 255 VAL B CA    1 ? ? 
ATOM   4033 C C     . VAL B 1 274 ? 21.623  58.153 20.467 1.000 24.197  0 255 VAL B C     1 ? ? 
ATOM   4034 O O     . VAL B 1 274 ? 21.951  58.513 19.334 1.000 25.842  0 255 VAL B O     1 ? ? 
ATOM   4035 C CB    . VAL B 1 274 ? 20.184  56.106 20.260 1.000 21.985  0 255 VAL B CB    1 ? ? 
ATOM   4036 C CG1   . VAL B 1 274 ? 18.879  55.468 20.623 1.000 20.972  0 255 VAL B CG1   1 ? ? 
ATOM   4037 C CG2   . VAL B 1 274 ? 20.361  55.988 18.760 1.000 21.541  0 255 VAL B CG2   1 ? ? 
ATOM   4038 N N     . ASP B 1 275 ? 22.464  58.182 21.508 1.000 24.900  0 256 ASP B N     1 ? ? 
ATOM   4039 C CA    . ASP B 1 275 ? 23.881  58.469 21.341 1.000 24.194  0 256 ASP B CA    1 ? ? 
ATOM   4040 C C     . ASP B 1 275 ? 24.618  57.130 21.324 1.000 24.064  0 256 ASP B C     1 ? ? 
ATOM   4041 O O     . ASP B 1 275 ? 24.657  56.438 22.345 1.000 23.417  0 256 ASP B O     1 ? ? 
ATOM   4042 C CB    . ASP B 1 275 ? 24.405  59.429 22.419 1.000 24.570  0 256 ASP B CB    1 ? ? 
ATOM   4043 C CG    . ASP B 1 275 ? 25.889  59.752 22.263 1.000 25.268  0 256 ASP B CG    1 ? ? 
ATOM   4044 O OD1   . ASP B 1 275 ? 26.524  59.186 21.331 1.000 23.477  0 256 ASP B OD1   1 ? ? 
ATOM   4045 O OD2   . ASP B 1 275 ? 26.431  60.549 23.065 1.000 27.865  0 256 ASP B OD2   1 ? ? 
ATOM   4046 N N     . LEU B 1 276 ? 25.196  56.769 20.167 1.000 23.269  0 257 LEU B N     1 ? ? 
ATOM   4047 C CA    . LEU B 1 276 ? 25.816  55.460 20.025 1.000 22.906  0 257 LEU B CA    1 ? ? 
ATOM   4048 C C     . LEU B 1 276 ? 27.325  55.517 20.263 1.000 23.077  0 257 LEU B C     1 ? ? 
ATOM   4049 O O     . LEU B 1 276 ? 28.005  54.535 19.981 1.000 23.468  0 257 LEU B O     1 ? ? 
ATOM   4050 C CB    . LEU B 1 276 ? 25.503  54.849 18.651 1.000 23.290  0 257 LEU B CB    1 ? ? 
ATOM   4051 C CG    . LEU B 1 276 ? 24.035  54.516 18.354 1.000 22.408  0 257 LEU B CG    1 ? ? 
ATOM   4052 C CD1   . LEU B 1 276 ? 23.898  53.840 16.997 1.000 20.823  0 257 LEU B CD1   1 ? ? 
ATOM   4053 C CD2   . LEU B 1 276 ? 23.417  53.645 19.433 1.000 21.388  0 257 LEU B CD2   1 ? ? 
ATOM   4054 N N     . GLY B 1 277 ? 27.845  56.658 20.742 1.000 22.668  0 258 GLY B N     1 ? ? 
ATOM   4055 C CA    . GLY B 1 277 ? 29.229  56.747 21.181 1.000 22.992  0 258 GLY B CA    1 ? ? 
ATOM   4056 C C     . GLY B 1 277 ? 30.245  56.624 20.043 1.000 23.835  0 258 GLY B C     1 ? ? 
ATOM   4057 O O     . GLY B 1 277 ? 29.922  56.896 18.885 1.000 25.106  0 258 GLY B O     1 ? ? 
ATOM   4058 N N     . ALA B 1 278 ? 31.471  56.215 20.398 1.000 23.105  0 259 ALA B N     1 ? ? 
ATOM   4059 C CA    . ALA B 1 278 ? 32.580  56.136 19.461 1.000 22.442  0 259 ALA B CA    1 ? ? 
ATOM   4060 C C     . ALA B 1 278 ? 33.625  55.142 19.957 1.000 23.249  0 259 ALA B C     1 ? ? 
ATOM   4061 O O     . ALA B 1 278 ? 33.715  54.876 21.156 1.000 21.957  0 259 ALA B O     1 ? ? 
ATOM   4062 C CB    . ALA B 1 278 ? 33.201  57.500 19.252 1.000 21.402  0 259 ALA B CB    1 ? ? 
ATOM   4063 N N     . GLY B 1 279 ? 34.426  54.632 19.006 1.000 24.369  0 260 GLY B N     1 ? ? 
ATOM   4064 C CA    . GLY B 1 279 ? 35.614  53.841 19.303 1.000 24.024  0 260 GLY B CA    1 ? ? 
ATOM   4065 C C     . GLY B 1 279 ? 35.399  52.334 19.144 1.000 23.925  0 260 GLY B C     1 ? ? 
ATOM   4066 O O     . GLY B 1 279 ? 34.283  51.854 18.953 1.000 25.241  0 260 GLY B O     1 ? ? 
ATOM   4067 N N     . THR B 1 280 ? 36.500  51.585 19.217 1.000 22.628  0 261 THR B N     1 ? ? 
ATOM   4068 C CA    . THR B 1 280 ? 36.432  50.133 19.174 1.000 22.667  0 261 THR B CA    1 ? ? 
ATOM   4069 C C     . THR B 1 280 ? 36.012  49.585 20.536 1.000 23.480  0 261 THR B C     1 ? ? 
ATOM   4070 O O     . THR B 1 280 ? 35.906  50.306 21.525 1.000 24.129  0 261 THR B O     1 ? ? 
ATOM   4071 C CB    . THR B 1 280 ? 37.759  49.515 18.723 1.000 21.615  0 261 THR B CB    1 ? ? 
ATOM   4072 O OG1   . THR B 1 280 ? 38.777  49.925 19.634 1.000 20.890  0 261 THR B OG1   1 ? ? 
ATOM   4073 C CG2   . THR B 1 280 ? 38.124  49.902 17.307 1.000 21.616  0 261 THR B CG2   1 ? ? 
ATOM   4074 N N     . ARG B 1 281 ? 35.713  48.294 20.568 1.000 23.080  0 262 ARG B N     1 ? ? 
ATOM   4075 C CA    . ARG B 1 281 ? 35.536  47.608 21.834 1.000 23.600  0 262 ARG B CA    1 ? ? 
ATOM   4076 C C     . ARG B 1 281 ? 36.417  46.358 21.817 1.000 23.296  0 262 ARG B C     1 ? ? 
ATOM   4077 O O     . ARG B 1 281 ? 36.501  45.774 20.766 1.000 21.948  0 262 ARG B O     1 ? ? 
ATOM   4078 C CB    . ARG B 1 281 ? 34.070  47.223 22.055 1.000 26.354  0 262 ARG B CB    1 ? ? 
ATOM   4079 C CG    . ARG B 1 281 ? 33.460  46.349 20.974 1.000 29.556  0 262 ARG B CG    1 ? ? 
ATOM   4080 C CD    . ARG B 1 281 ? 32.032  46.026 21.293 1.000 28.081  0 262 ARG B CD    1 ? ? 
ATOM   4081 N NE    . ARG B 1 281 ? 31.884  45.337 22.560 1.000 27.344  0 262 ARG B NE    1 ? ? 
ATOM   4082 C CZ    . ARG B 1 281 ? 30.739  44.837 22.952 1.000 27.130  0 262 ARG B CZ    1 ? ? 
ATOM   4083 N NH1   . ARG B 1 281 ? 29.719  44.930 22.131 1.000 27.797  0 262 ARG B NH1   1 ? ? 
ATOM   4084 N NH2   . ARG B 1 281 ? 30.603  44.239 24.124 1.000 27.847  0 262 ARG B NH2   1 ? ? 
HETATM 4085 N N     . SAH C 2 .   ? 7.120   22.500 43.053 1.000 21.619  0 301 SAH A N     1 ? ? 
HETATM 4086 C CA    . SAH C 2 .   ? 7.529   23.485 44.090 1.000 21.211  0 301 SAH A CA    1 ? ? 
HETATM 4087 C CB    . SAH C 2 .   ? 6.322   24.270 44.606 1.000 22.553  0 301 SAH A CB    1 ? ? 
HETATM 4088 C CG    . SAH C 2 .   ? 6.332   25.680 44.069 1.000 26.573  0 301 SAH A CG    1 ? ? 
HETATM 4089 S SD    . SAH C 2 .   ? 4.829   26.645 44.328 1.000 30.912  0 301 SAH A SD    1 ? ? 
HETATM 4090 C C     . SAH C 2 .   ? 8.280   22.800 45.243 1.000 20.237  0 301 SAH A C     1 ? ? 
HETATM 4091 O O     . SAH C 2 .   ? 8.530   23.421 46.280 1.000 18.780  0 301 SAH A O     1 ? ? 
HETATM 4092 O OXT   . SAH C 2 .   ? 8.669   21.627 45.179 1.000 19.376  0 301 SAH A OXT   1 ? ? 
HETATM 4093 C "C5'" . SAH C 2 .   ? 4.679   27.534 42.756 1.000 29.774  0 301 SAH A "C5'" 1 ? ? 
HETATM 4094 C "C4'" . SAH C 2 .   ? 5.682   28.651 42.605 1.000 27.342  0 301 SAH A "C4'" 1 ? ? 
HETATM 4095 O "O4'" . SAH C 2 .   ? 5.469   29.360 41.365 1.000 26.224  0 301 SAH A "O4'" 1 ? ? 
HETATM 4096 C "C3'" . SAH C 2 .   ? 5.661   29.724 43.695 1.000 27.035  0 301 SAH A "C3'" 1 ? ? 
HETATM 4097 O "O3'" . SAH C 2 .   ? 6.891   29.675 44.411 1.000 31.507  0 301 SAH A "O3'" 1 ? ? 
HETATM 4098 C "C2'" . SAH C 2 .   ? 5.469   31.032 42.914 1.000 24.248  0 301 SAH A "C2'" 1 ? ? 
HETATM 4099 O "O2'" . SAH C 2 .   ? 6.193   32.132 43.404 1.000 22.725  0 301 SAH A "O2'" 1 ? ? 
HETATM 4100 C "C1'" . SAH C 2 .   ? 6.002   30.647 41.544 1.000 24.295  0 301 SAH A "C1'" 1 ? ? 
HETATM 4101 N N9    . SAH C 2 .   ? 5.541   31.497 40.453 1.000 22.474  0 301 SAH A N9    1 ? ? 
HETATM 4102 C C8    . SAH C 2 .   ? 4.282   32.016 40.332 1.000 22.354  0 301 SAH A C8    1 ? ? 
HETATM 4103 N N7    . SAH C 2 .   ? 4.116   32.726 39.251 1.000 22.329  0 301 SAH A N7    1 ? ? 
HETATM 4104 C C5    . SAH C 2 .   ? 5.332   32.647 38.591 1.000 21.614  0 301 SAH A C5    1 ? ? 
HETATM 4105 C C6    . SAH C 2 .   ? 5.777   33.177 37.359 1.000 20.757  0 301 SAH A C6    1 ? ? 
HETATM 4106 N N6    . SAH C 2 .   ? 5.015   33.915 36.555 1.000 19.599  0 301 SAH A N6    1 ? ? 
HETATM 4107 N N1    . SAH C 2 .   ? 7.039   32.870 36.962 1.000 20.680  0 301 SAH A N1    1 ? ? 
HETATM 4108 C C2    . SAH C 2 .   ? 7.798   32.130 37.783 1.000 21.033  0 301 SAH A C2    1 ? ? 
HETATM 4109 N N3    . SAH C 2 .   ? 7.493   31.604 38.971 1.000 22.733  0 301 SAH A N3    1 ? ? 
HETATM 4110 C C4    . SAH C 2 .   ? 6.224   31.889 39.324 1.000 22.159  0 301 SAH A C4    1 ? ? 
HETATM 4111 C C1    . QAP D 3 .   ? -7.867  31.155 47.288 1.000 64.298  0 302 QAP A C1    1 ? ? 
HETATM 4112 O O1    . QAP D 3 .   ? -5.863  29.894 48.003 1.000 70.943  0 302 QAP A O1    1 ? ? 
HETATM 4113 C C2    . QAP D 3 .   ? -9.122  30.803 48.060 1.000 65.134  0 302 QAP A C2    1 ? ? 
HETATM 4114 O O2    . QAP D 3 .   ? -2.816  24.836 50.608 1.000 54.784  0 302 QAP A O2    1 ? ? 
HETATM 4115 C C3    . QAP D 3 .   ? -6.612  31.186 48.144 1.000 69.080  0 302 QAP A C3    1 ? ? 
HETATM 4116 O O3    . QAP D 3 .   ? -1.464  23.649 48.517 0.500 59.386  0 302 QAP A O3    1 ? ? 
HETATM 4117 C C4    . QAP D 3 .   ? -9.183  30.919 49.449 1.000 63.562  0 302 QAP A C4    1 ? ? 
HETATM 4118 O O4    . QAP D 3 .   ? -5.820  29.189 50.152 1.000 71.840  0 302 QAP A O4    1 ? ? 
HETATM 4119 C C5    . QAP D 3 .   ? -10.252 30.352 47.395 1.000 59.242  0 302 QAP A C5    1 ? ? 
HETATM 4120 C C6    . QAP D 3 .   ? -4.738  26.088 47.728 1.000 60.924  0 302 QAP A C6    1 ? ? 
HETATM 4121 C C7    . QAP D 3 .   ? -10.334 30.578 50.147 1.000 58.563  0 302 QAP A C7    1 ? ? 
HETATM 4122 C C8    . QAP D 3 .   ? -11.401 30.013 48.096 1.000 58.810  0 302 QAP A C8    1 ? ? 
HETATM 4123 C C9    . QAP D 3 .   ? -11.440 30.116 49.467 1.000 58.547  0 302 QAP A C9    1 ? ? 
HETATM 4124 C C10   . QAP D 3 .   ? -4.300  25.854 49.042 1.000 60.587  0 302 QAP A C10   1 ? ? 
HETATM 4125 C C11   . QAP D 3 .   ? -4.035  25.484 46.689 1.000 57.318  0 302 QAP A C11   1 ? ? 
HETATM 4126 C C12   . QAP D 3 .   ? -5.890  26.966 47.508 1.000 61.025  0 302 QAP A C12   1 ? ? 
HETATM 4127 C C13   . QAP D 3 .   ? -3.212  25.045 49.313 1.000 58.604  0 302 QAP A C13   1 ? ? 
HETATM 4128 C C14   . QAP D 3 .   ? -6.049  28.973 48.964 1.000 70.743  0 302 QAP A C14   1 ? ? 
HETATM 4129 C C15   . QAP D 3 .   ? -2.532  24.446 48.245 0.500 57.749  0 302 QAP A C15   1 ? ? 
HETATM 4130 C C16   . QAP D 3 .   ? -2.937  24.672 46.941 1.000 55.926  0 302 QAP A C16   1 ? ? 
HETATM 4131 C C17   . QAP D 3 .   ? -6.528  27.691 48.431 1.000 65.598  0 302 QAP A C17   1 ? ? 
HETATM 4132 C C1    . QAP E 3 .   ? -3.819  32.232 51.259 1.000 63.084  0 303 QAP A C1    1 ? ? 
HETATM 4133 O O1    . QAP E 3 .   ? -3.020  33.080 49.137 1.000 62.987  0 303 QAP A O1    1 ? ? 
HETATM 4134 C C2    . QAP E 3 .   ? -2.910  32.019 52.448 1.000 66.218  0 303 QAP A C2    1 ? ? 
HETATM 4135 O O2    . QAP E 3 .   ? 0.847   28.862 44.609 1.000 103.675 0 303 QAP A O2    1 ? ? 
HETATM 4136 C C3    . QAP E 3 .   ? -3.230  31.833 49.932 1.000 62.275  0 303 QAP A C3    1 ? ? 
HETATM 4137 O O3    . QAP E 3 .   ? -0.679  26.811 45.645 1.000 98.013  0 303 QAP A O3    1 ? ? 
HETATM 4138 C C4    . QAP E 3 .   ? -3.307  31.206 53.501 1.000 66.808  0 303 QAP A C4    1 ? ? 
HETATM 4139 O O4    . QAP E 3 .   ? -4.780  34.025 48.119 1.000 55.118  0 303 QAP A O4    1 ? ? 
HETATM 4140 C C5    . QAP E 3 .   ? -1.674  32.649 52.538 1.000 66.837  0 303 QAP A C5    1 ? ? 
HETATM 4141 C C6    . QAP E 3 .   ? -1.743  30.755 46.417 1.000 91.032  0 303 QAP A C6    1 ? ? 
HETATM 4142 C C7    . QAP E 3 .   ? -2.484  31.016 54.603 1.000 67.560  0 303 QAP A C7    1 ? ? 
HETATM 4143 C C8    . QAP E 3 .   ? -0.851  32.459 53.639 1.000 65.677  0 303 QAP A C8    1 ? ? 
HETATM 4144 C C9    . QAP E 3 .   ? -1.259  31.643 54.669 1.000 68.724  0 303 QAP A C9    1 ? ? 
HETATM 4145 C C10   . QAP E 3 .   ? -0.613  30.464 45.638 1.000 95.686  0 303 QAP A C10   1 ? ? 
HETATM 4146 C C11   . QAP E 3 .   ? -2.485  29.695 46.922 1.000 93.009  0 303 QAP A C11   1 ? ? 
HETATM 4147 C C12   . QAP E 3 .   ? -2.136  32.135 46.696 1.000 81.361  0 303 QAP A C12   1 ? ? 
HETATM 4148 C C13   . QAP E 3 .   ? -0.250  29.153 45.371 1.000 101.704 0 303 QAP A C13   1 ? ? 
HETATM 4149 C C14   . QAP E 3 .   ? -3.815  33.292 48.077 1.000 61.807  0 303 QAP A C14   1 ? ? 
HETATM 4150 C C15   . QAP E 3 .   ? -1.020  28.106 45.894 1.000 100.427 0 303 QAP A C15   1 ? ? 
HETATM 4151 C C16   . QAP E 3 .   ? -2.126  28.382 46.669 1.000 97.378  0 303 QAP A C16   1 ? ? 
HETATM 4152 C C17   . QAP E 3 .   ? -3.366  32.597 46.867 1.000 66.175  0 303 QAP A C17   1 ? ? 
HETATM 4153 N N     . SAH F 2 .   ? 15.840  50.233 10.008 1.000 52.945  0 301 SAH B N     1 ? ? 
HETATM 4154 C CA    . SAH F 2 .   ? 16.362  48.839 9.980  1.000 52.435  0 301 SAH B CA    1 ? ? 
HETATM 4155 C CB    . SAH F 2 .   ? 16.256  48.257 8.567  1.000 51.915  0 301 SAH B CB    1 ? ? 
HETATM 4156 C CG    . SAH F 2 .   ? 14.829  48.006 8.145  1.000 49.153  0 301 SAH B CG    1 ? ? 
HETATM 4157 S SD    . SAH F 2 .   ? 14.430  48.651 6.529  1.000 46.001  0 301 SAH B SD    1 ? ? 
HETATM 4158 C C     . SAH F 2 .   ? 17.829  48.870 10.406 1.000 53.220  0 301 SAH B C     1 ? ? 
HETATM 4159 O O     . SAH F 2 .   ? 18.435  47.882 10.844 1.000 51.514  0 301 SAH B O     1 ? ? 
HETATM 4160 O OXT   . SAH F 2 .   ? 18.394  49.950 10.295 1.000 48.136  0 301 SAH B OXT   1 ? ? 
HETATM 4161 C "C5'" . SAH F 2 .   ? 14.247  47.103 5.621  1.000 45.221  0 301 SAH B "C5'" 1 ? ? 
HETATM 4162 C "C4'" . SAH F 2 .   ? 15.435  46.889 4.709  1.000 42.285  0 301 SAH B "C4'" 1 ? ? 
HETATM 4163 O "O4'" . SAH F 2 .   ? 15.429  45.518 4.256  1.000 37.690  0 301 SAH B "O4'" 1 ? ? 
HETATM 4164 C "C3'" . SAH F 2 .   ? 15.431  47.771 3.448  1.000 38.830  0 301 SAH B "C3'" 1 ? ? 
HETATM 4165 O "O3'" . SAH F 2 .   ? 16.528  48.676 3.418  1.000 38.323  0 301 SAH B "O3'" 1 ? ? 
HETATM 4166 C "C2'" . SAH F 2 .   ? 15.492  46.790 2.271  1.000 38.180  0 301 SAH B "C2'" 1 ? ? 
HETATM 4167 O "O2'" . SAH F 2 .   ? 16.453  47.155 1.304  1.000 43.711  0 301 SAH B "O2'" 1 ? ? 
HETATM 4168 C "C1'" . SAH F 2 .   ? 15.909  45.482 2.935  1.000 36.869  0 301 SAH B "C1'" 1 ? ? 
HETATM 4169 N N9    . SAH F 2 .   ? 15.359  44.303 2.284  1.000 33.302  0 301 SAH B N9    1 ? ? 
HETATM 4170 C C8    . SAH F 2 .   ? 14.087  44.137 1.799  1.000 31.914  0 301 SAH B C8    1 ? ? 
HETATM 4171 N N7    . SAH F 2 .   ? 13.884  42.950 1.284  1.000 32.375  0 301 SAH B N7    1 ? ? 
HETATM 4172 C C5    . SAH F 2 .   ? 15.100  42.301 1.422  1.000 32.484  0 301 SAH B C5    1 ? ? 
HETATM 4173 C C6    . SAH F 2 .   ? 15.540  41.013 1.060  1.000 33.517  0 301 SAH B C6    1 ? ? 
HETATM 4174 N N6    . SAH F 2 .   ? 14.775  40.117 0.448  1.000 35.994  0 301 SAH B N6    1 ? ? 
HETATM 4175 N N1    . SAH F 2 .   ? 16.821  40.679 1.335  1.000 31.049  0 301 SAH B N1    1 ? ? 
HETATM 4176 C C2    . SAH F 2 .   ? 17.589  41.584 1.945  1.000 32.178  0 301 SAH B C2    1 ? ? 
HETATM 4177 N N3    . SAH F 2 .   ? 17.290  42.818 2.338  1.000 33.580  0 301 SAH B N3    1 ? ? 
HETATM 4178 C C4    . SAH F 2 .   ? 16.017  43.125 2.039  1.000 32.789  0 301 SAH B C4    1 ? ? 
HETATM 4179 O O     . HOH G 4 .   ? 10.486  22.794 42.466 1.000 6.449   0 401 HOH A O     1 ? ? 
HETATM 4180 O O     . HOH G 4 .   ? 7.184   37.518 50.267 1.000 19.090  0 402 HOH A O     1 ? ? 
HETATM 4181 O O     . HOH G 4 .   ? -7.887  27.288 43.827 1.000 26.639  0 403 HOH A O     1 ? ? 
HETATM 4182 O O     . HOH G 4 .   ? -19.745 27.134 33.372 1.000 12.798  0 404 HOH A O     1 ? ? 
HETATM 4183 O O     . HOH G 4 .   ? 17.000  34.111 45.843 1.000 23.139  0 405 HOH A O     1 ? ? 
HETATM 4184 O O     . HOH G 4 .   ? -15.258 16.335 55.657 1.000 11.565  0 406 HOH A O     1 ? ? 
HETATM 4185 O O     . HOH G 4 .   ? 22.653  18.841 56.520 1.000 16.121  0 407 HOH A O     1 ? ? 
HETATM 4186 O O     . HOH G 4 .   ? 6.893   39.852 43.622 1.000 22.669  0 408 HOH A O     1 ? ? 
HETATM 4187 O O     . HOH G 4 .   ? 8.464   14.492 61.161 1.000 13.440  0 409 HOH A O     1 ? ? 
HETATM 4188 O O     . HOH G 4 .   ? 7.371   8.486  50.117 1.000 11.903  0 410 HOH A O     1 ? ? 
HETATM 4189 O O     . HOH G 4 .   ? 8.155   25.860 47.237 1.000 32.311  0 411 HOH A O     1 ? ? 
HETATM 4190 O O     . HOH G 4 .   ? -22.866 14.458 36.965 1.000 23.877  0 412 HOH A O     1 ? ? 
HETATM 4191 O O     . HOH G 4 .   ? -8.194  15.415 23.573 1.000 25.718  0 413 HOH A O     1 ? ? 
HETATM 4192 O O     . HOH G 4 .   ? -21.663 19.170 48.891 1.000 14.529  0 414 HOH A O     1 ? ? 
HETATM 4193 O O     . HOH G 4 .   ? 7.762   12.119 57.671 1.000 18.702  0 415 HOH A O     1 ? ? 
HETATM 4194 O O     . HOH G 4 .   ? -7.938  10.582 55.627 1.000 18.963  0 416 HOH A O     1 ? ? 
HETATM 4195 O O     . HOH G 4 .   ? 8.109   16.397 50.462 1.000 8.949   0 417 HOH A O     1 ? ? 
HETATM 4196 O O     . HOH G 4 .   ? -18.924 28.144 61.865 1.000 17.889  0 418 HOH A O     1 ? ? 
HETATM 4197 O O     . HOH G 4 .   ? 17.920  13.267 45.967 1.000 14.510  0 419 HOH A O     1 ? ? 
HETATM 4198 O O     . HOH G 4 .   ? 12.122  31.014 50.138 1.000 20.850  0 420 HOH A O     1 ? ? 
HETATM 4199 O O     . HOH G 4 .   ? 3.485   18.107 58.731 1.000 3.349   0 421 HOH A O     1 ? ? 
HETATM 4200 O O     . HOH G 4 .   ? 17.771  18.917 63.549 1.000 22.777  0 422 HOH A O     1 ? ? 
HETATM 4201 O O     . HOH G 4 .   ? -3.060  21.349 47.893 1.000 35.060  0 423 HOH A O     1 ? ? 
HETATM 4202 O O     . HOH G 4 .   ? -23.228 12.008 50.031 1.000 20.823  0 424 HOH A O     1 ? ? 
HETATM 4203 O O     . HOH G 4 .   ? 27.941  16.867 48.255 1.000 23.398  0 425 HOH A O     1 ? ? 
HETATM 4204 O O     . HOH G 4 .   ? -7.221  11.537 38.775 1.000 5.979   0 426 HOH A O     1 ? ? 
HETATM 4205 O O     . HOH G 4 .   ? 3.585   37.503 34.262 1.000 11.028  0 427 HOH A O     1 ? ? 
HETATM 4206 O O     . HOH G 4 .   ? 12.117  15.663 53.926 1.000 7.851   0 428 HOH A O     1 ? ? 
HETATM 4207 O O     . HOH G 4 .   ? -20.648 25.647 51.659 1.000 19.558  0 429 HOH A O     1 ? ? 
HETATM 4208 O O     . HOH G 4 .   ? 4.981   22.534 20.757 1.000 36.266  0 430 HOH A O     1 ? ? 
HETATM 4209 O O     . HOH G 4 .   ? -14.089 30.394 52.481 1.000 26.947  0 431 HOH A O     1 ? ? 
HETATM 4210 O O     . HOH G 4 .   ? -12.057 34.109 32.755 1.000 18.890  0 432 HOH A O     1 ? ? 
HETATM 4211 O O     . HOH G 4 .   ? 17.719  25.441 24.752 1.000 7.287   0 433 HOH A O     1 ? ? 
HETATM 4212 O O     . HOH G 4 .   ? -10.600 11.611 38.249 1.000 12.933  0 434 HOH A O     1 ? ? 
HETATM 4213 O O     . HOH G 4 .   ? 7.531   30.615 28.606 1.000 16.784  0 435 HOH A O     1 ? ? 
HETATM 4214 O O     . HOH G 4 .   ? 6.535   29.830 25.825 1.000 8.233   0 436 HOH A O     1 ? ? 
HETATM 4215 O O     . HOH G 4 .   ? -0.451  17.014 51.710 1.000 3.382   0 437 HOH A O     1 ? ? 
HETATM 4216 O O     . HOH G 4 .   ? 22.218  30.193 32.956 1.000 23.039  0 438 HOH A O     1 ? ? 
HETATM 4217 O O     . HOH G 4 .   ? -10.466 25.495 61.893 1.000 18.766  0 439 HOH A O     1 ? ? 
HETATM 4218 O O     . HOH G 4 .   ? -6.857  14.481 46.269 1.000 8.632   0 440 HOH A O     1 ? ? 
HETATM 4219 O O     . HOH G 4 .   ? 1.518   29.550 41.842 1.000 4.016   0 441 HOH A O     1 ? ? 
HETATM 4220 O O     . HOH G 4 .   ? 13.963  36.629 28.680 1.000 13.738  0 442 HOH A O     1 ? ? 
HETATM 4221 O O     . HOH G 4 .   ? -7.113  13.170 49.045 1.000 6.515   0 443 HOH A O     1 ? ? 
HETATM 4222 O O     . HOH G 4 .   ? -9.073  31.221 25.390 1.000 12.426  0 444 HOH A O     1 ? ? 
HETATM 4223 O O     . HOH G 4 .   ? -6.970  10.484 36.634 1.000 7.234   0 445 HOH A O     1 ? ? 
HETATM 4224 O O     . HOH G 4 .   ? 5.217   13.051 25.244 1.000 13.021  0 446 HOH A O     1 ? ? 
HETATM 4225 O O     . HOH G 4 .   ? 20.738  26.207 42.684 1.000 22.396  0 447 HOH A O     1 ? ? 
HETATM 4226 O O     . HOH G 4 .   ? -11.022 14.158 26.882 1.000 6.840   0 448 HOH A O     1 ? ? 
HETATM 4227 O O     . HOH G 4 .   ? -21.085 14.240 47.065 1.000 23.924  0 449 HOH A O     1 ? ? 
HETATM 4228 O O     . HOH G 4 .   ? 23.271  21.904 36.109 1.000 12.571  0 450 HOH A O     1 ? ? 
HETATM 4229 O O     . HOH G 4 .   ? -4.296  35.930 34.408 1.000 16.802  0 451 HOH A O     1 ? ? 
HETATM 4230 O O     . HOH G 4 .   ? -3.839  25.607 43.571 1.000 21.617  0 452 HOH A O     1 ? ? 
HETATM 4231 O O     . HOH G 4 .   ? -22.343 13.552 34.527 1.000 21.443  0 453 HOH A O     1 ? ? 
HETATM 4232 O O     . HOH G 4 .   ? -3.565  10.542 25.685 1.000 11.177  0 454 HOH A O     1 ? ? 
HETATM 4233 O O     . HOH G 4 .   ? 2.706   17.384 19.184 1.000 33.708  0 455 HOH A O     1 ? ? 
HETATM 4234 O O     . HOH G 4 .   ? 0.627   19.336 48.447 1.000 19.090  0 456 HOH A O     1 ? ? 
HETATM 4235 O O     . HOH G 4 .   ? -11.075 10.514 60.933 1.000 4.111   0 457 HOH A O     1 ? ? 
HETATM 4236 O O     . HOH G 4 .   ? -16.639 8.142  30.805 1.000 11.735  0 458 HOH A O     1 ? ? 
HETATM 4237 O O     . HOH G 4 .   ? 1.819   4.810  56.803 1.000 28.065  0 459 HOH A O     1 ? ? 
HETATM 4238 O O     . HOH G 4 .   ? 0.295   9.533  26.102 1.000 19.750  0 460 HOH A O     1 ? ? 
HETATM 4239 O O     . HOH G 4 .   ? 27.289  11.356 37.483 1.000 8.394   0 461 HOH A O     1 ? ? 
HETATM 4240 O O     . HOH G 4 .   ? 22.865  17.836 30.526 1.000 19.379  0 462 HOH A O     1 ? ? 
HETATM 4241 O O     . HOH G 4 .   ? 15.964  18.158 23.696 1.000 20.552  0 463 HOH A O     1 ? ? 
HETATM 4242 O O     . HOH G 4 .   ? -11.100 14.833 21.151 1.000 23.999  0 464 HOH A O     1 ? ? 
HETATM 4243 O O     . HOH G 4 .   ? 24.343  24.381 47.613 1.000 15.996  0 465 HOH A O     1 ? ? 
HETATM 4244 O O     . HOH G 4 .   ? -21.654 10.008 37.411 1.000 25.746  0 466 HOH A O     1 ? ? 
HETATM 4245 O O     . HOH G 4 .   ? 2.366   6.670  28.057 1.000 23.306  0 467 HOH A O     1 ? ? 
HETATM 4246 O O     . HOH G 4 .   ? 17.386  30.517 26.592 1.000 13.223  0 468 HOH A O     1 ? ? 
HETATM 4247 O O     . HOH H 4 .   ? 18.935  52.184 -3.437 1.000 25.233  0 401 HOH B O     1 ? ? 
HETATM 4248 O O     . HOH H 4 .   ? 17.488  43.623 27.044 1.000 28.771  0 402 HOH B O     1 ? ? 
HETATM 4249 O O     . HOH H 4 .   ? -2.278  37.639 25.794 1.000 21.960  0 403 HOH B O     1 ? ? 
HETATM 4250 O O     . HOH H 4 .   ? 21.355  61.912 21.256 1.000 30.642  0 404 HOH B O     1 ? ? 
HETATM 4251 O O     . HOH H 4 .   ? -4.749  41.904 24.966 1.000 19.343  0 405 HOH B O     1 ? ? 
HETATM 4252 O O     . HOH H 4 .   ? 7.920   59.375 12.982 1.000 21.937  0 406 HOH B O     1 ? ? 
HETATM 4253 O O     . HOH H 4 .   ? 20.566  60.121 24.174 1.000 15.697  0 407 HOH B O     1 ? ? 
HETATM 4254 O O     . HOH H 4 .   ? 13.021  32.887 -2.745 1.000 28.246  0 408 HOH B O     1 ? ? 
HETATM 4255 O O     . HOH H 4 .   ? 34.494  54.382 9.822  1.000 19.638  0 409 HOH B O     1 ? ? 
HETATM 4256 O O     . HOH H 4 .   ? -9.241  43.273 3.619  1.000 14.965  0 410 HOH B O     1 ? ? 
HETATM 4257 O O     . HOH H 4 .   ? 24.605  50.891 21.389 1.000 15.084  0 411 HOH B O     1 ? ? 
HETATM 4258 O O     . HOH H 4 .   ? 17.435  31.428 23.881 1.000 32.790  0 412 HOH B O     1 ? ? 
HETATM 4259 O O     . HOH H 4 .   ? 23.480  53.799 13.815 1.000 22.904  0 413 HOH B O     1 ? ? 
HETATM 4260 O O     . HOH H 4 .   ? 37.649  53.475 15.707 1.000 20.915  0 414 HOH B O     1 ? ? 
HETATM 4261 O O     . HOH H 4 .   ? -1.673  33.226 20.254 1.000 12.266  0 415 HOH B O     1 ? ? 
HETATM 4262 O O     . HOH H 4 .   ? 6.679   40.893 8.129  1.000 18.267  0 416 HOH B O     1 ? ? 
HETATM 4263 O O     . HOH H 4 .   ? -6.437  43.356 -1.028 1.000 25.030  0 417 HOH B O     1 ? ? 
HETATM 4264 O O     . HOH H 4 .   ? 11.355  58.125 15.887 1.000 10.052  0 418 HOH B O     1 ? ? 
HETATM 4265 O O     . HOH H 4 .   ? 13.907  65.470 11.753 1.000 26.632  0 419 HOH B O     1 ? ? 
HETATM 4266 O O     . HOH H 4 .   ? -2.090  52.174 2.896  1.000 28.227  0 420 HOH B O     1 ? ? 
HETATM 4267 O O     . HOH H 4 .   ? 40.490  52.160 19.345 1.000 17.846  0 421 HOH B O     1 ? ? 
HETATM 4268 O O     . HOH H 4 .   ? 7.273   66.136 22.893 1.000 12.374  0 422 HOH B O     1 ? ? 
HETATM 4269 O O     . HOH H 4 .   ? 6.692   56.637 24.690 1.000 28.560  0 423 HOH B O     1 ? ? 
HETATM 4270 O O     . HOH H 4 .   ? 27.134  48.568 -0.567 1.000 15.779  0 424 HOH B O     1 ? ? 
HETATM 4271 O O     . HOH H 4 .   ? 1.511   62.257 21.426 1.000 37.609  0 425 HOH B O     1 ? ? 
HETATM 4272 O O     . HOH H 4 .   ? 0.669   47.203 7.961  1.000 26.956  0 426 HOH B O     1 ? ? 
HETATM 4273 O O     . HOH H 4 .   ? 19.936  29.089 14.833 1.000 21.211  0 427 HOH B O     1 ? ? 
HETATM 4274 O O     . HOH H 4 .   ? 3.516   47.792 -3.041 1.000 37.485  0 428 HOH B O     1 ? ? 
HETATM 4275 O O     . HOH H 4 .   ? 29.820  65.376 3.297  1.000 30.854  0 429 HOH B O     1 ? ? 
HETATM 4276 O O     . HOH H 4 .   ? -7.961  66.199 20.238 1.000 14.201  0 430 HOH B O     1 ? ? 
HETATM 4277 O O     . HOH H 4 .   ? 8.873   54.182 12.817 1.000 17.175  0 431 HOH B O     1 ? ? 
HETATM 4278 O O     . HOH H 4 .   ? 18.424  57.034 23.919 1.000 17.363  0 432 HOH B O     1 ? ? 
HETATM 4279 O O     . HOH H 4 .   ? 13.157  31.526 21.522 1.000 8.647   0 433 HOH B O     1 ? ? 
HETATM 4280 O O     . HOH H 4 .   ? 22.792  62.849 16.844 1.000 24.223  0 434 HOH B O     1 ? ? 
HETATM 4281 O O     . HOH H 4 .   ? 22.756  38.222 32.774 1.000 27.262  0 435 HOH B O     1 ? ? 
HETATM 4282 O O     . HOH H 4 .   ? 15.044  56.948 9.636  1.000 5.969   0 436 HOH B O     1 ? ? 
HETATM 4283 O O     . HOH H 4 .   ? -17.742 42.080 10.515 1.000 30.785  0 437 HOH B O     1 ? ? 
HETATM 4284 O O     . HOH H 4 .   ? -11.420 40.240 20.832 1.000 20.011  0 438 HOH B O     1 ? ? 
HETATM 4285 O O     . HOH H 4 .   ? 12.616  61.802 9.012  1.000 13.367  0 439 HOH B O     1 ? ? 
HETATM 4286 O O     . HOH H 4 .   ? -3.724  56.701 21.955 1.000 13.536  0 440 HOH B O     1 ? ? 
HETATM 4287 O O     . HOH H 4 .   ? 2.669   45.901 22.893 1.000 11.698  0 441 HOH B O     1 ? ? 
HETATM 4288 O O     . HOH H 4 .   ? -5.817  33.906 25.663 1.000 17.575  0 442 HOH B O     1 ? ? 
HETATM 4289 O O     . HOH H 4 .   ? 34.275  54.356 24.217 1.000 18.335  0 443 HOH B O     1 ? ? 
HETATM 4290 O O     . HOH H 4 .   ? 12.542  28.714 20.862 1.000 16.251  0 444 HOH B O     1 ? ? 
HETATM 4291 O O     . HOH H 4 .   ? 12.586  23.765 22.535 1.000 27.496  0 445 HOH B O     1 ? ? 
HETATM 4292 O O     . HOH H 4 .   ? 28.444  59.157 7.645  1.000 22.656  0 446 HOH B O     1 ? ? 
HETATM 4293 O O     . HOH H 4 .   ? 33.286  62.091 13.537 1.000 14.739  0 447 HOH B O     1 ? ? 
HETATM 4294 O O     . HOH H 4 .   ? -9.090  49.571 0.808  1.000 17.388  0 448 HOH B O     1 ? ? 
HETATM 4295 O O     . HOH H 4 .   ? -11.327 43.172 24.043 1.000 10.990  0 449 HOH B O     1 ? ? 
HETATM 4296 O O     . HOH H 4 .   ? 21.185  57.337 24.400 1.000 10.552  0 450 HOH B O     1 ? ? 
HETATM 4297 O O     . HOH H 4 .   ? 32.098  40.985 12.167 1.000 30.760  0 451 HOH B O     1 ? ? 
HETATM 4298 O O     . HOH H 4 .   ? 11.372  46.778 3.741  1.000 18.901  0 452 HOH B O     1 ? ? 
HETATM 4299 O O     . HOH H 4 .   ? 13.848  56.926 22.295 1.000 12.158  0 453 HOH B O     1 ? ? 
HETATM 4300 O O     . HOH H 4 .   ? 30.334  47.651 8.084  1.000 13.705  0 454 HOH B O     1 ? ? 
HETATM 4301 O O     . HOH H 4 .   ? -13.901 40.477 21.692 1.000 11.884  0 455 HOH B O     1 ? ? 
HETATM 4302 O O     . HOH H 4 .   ? -13.367 38.448 23.966 1.000 20.334  0 456 HOH B O     1 ? ? 
# 
