data_8KDJ
# 
_entry.id   8KDJ 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8KDJ         pdb_00008kdj 10.2210/pdb8kdj/pdb 
WWPDB D_1300040170 ?            ?                   
EMDB  EMD-37138    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1  'Structure model' 1 0 2025-02-12 ? 
2  'EM metadata'     1 0 2025-02-12 ? 
3  FSC               1 0 2025-02-12 ? 
4  'Half map'        1 0 2025-02-12 1 
5  'Half map'        1 0 2025-02-12 2 
6  Image             1 0 2025-02-12 ? 
7  Mask              1 0 2025-02-12 ? 
8  'Primary map'     1 0 2025-02-12 ? 
9  'Structure model' 1 1 2025-02-26 ? 
10 'EM metadata'     1 1 2025-02-26 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 Mask              repository 'Initial release' ? ? 
8 8 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 9  'Structure model' 'Data collection'      
2 9  'Structure model' 'Database references'  
3 10 'EM metadata'     'Database references'  
4 10 'EM metadata'     'Experimental summary' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 9  'Structure model' citation        
2 9  'Structure model' citation_author 
3 9  'Structure model' em_admin        
4 10 'EM metadata'     citation        
5 10 'EM metadata'     citation_author 
6 10 'EM metadata'     em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  9  'Structure model' '_citation.country'                 
2  9  'Structure model' '_citation.journal_abbrev'          
3  9  'Structure model' '_citation.journal_id_CSD'          
4  9  'Structure model' '_citation.journal_id_ISSN'         
5  9  'Structure model' '_citation.journal_volume'          
6  9  'Structure model' '_citation.page_first'              
7  9  'Structure model' '_citation.page_last'               
8  9  'Structure model' '_citation.pdbx_database_id_DOI'    
9  9  'Structure model' '_citation.pdbx_database_id_PubMed' 
10 9  'Structure model' '_citation.title'                   
11 9  'Structure model' '_citation.year'                    
12 9  'Structure model' '_em_admin.last_update'             
13 10 'EM metadata'     '_citation.country'                 
14 10 'EM metadata'     '_citation.journal_abbrev'          
15 10 'EM metadata'     '_citation.journal_id_CSD'          
16 10 'EM metadata'     '_citation.journal_id_ISSN'         
17 10 'EM metadata'     '_citation.journal_volume'          
18 10 'EM metadata'     '_citation.page_first'              
19 10 'EM metadata'     '_citation.page_last'               
20 10 'EM metadata'     '_citation.pdbx_database_id_DOI'    
21 10 'EM metadata'     '_citation.pdbx_database_id_PubMed' 
22 10 'EM metadata'     '_citation.title'                   
23 10 'EM metadata'     '_citation.year'                    
24 10 'EM metadata'     '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8KDJ 
_pdbx_database_status.recvd_initial_deposition_date   2023-08-09 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'Structure of apo inward-open LAT1-CD98h in nanodisc, focused on TMD'        EMD-37138 'associated EM volume' 
EMDB 'Structure of apo inward-open LAT1-CD98hc-Fab170 in nanodisc, consensus map' EMD-37137 'other EM volume'      
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              ri.yon.df@yokohama-cu.ac.jp 
_pdbx_contact_author.name_first         Yongchan 
_pdbx_contact_author.name_last          Lee 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1507-805X 
# 
_audit_author.name               'Lee, Y.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                1635 
_citation.page_last                 1635 
_citation.title                     'Structural basis of anticancer drug recognition and amino acid transport by LAT1.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-56903-w 
_citation.pdbx_database_id_PubMed   39952931 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Lee, Y.'          1  0000-0002-1507-805X 
primary 'Jin, C.'          2  ?                   
primary 'Ohgaki, R.'       3  0000-0002-6894-7239 
primary 'Xu, M.'           4  ?                   
primary 'Ogasawara, S.'    5  0000-0001-6908-9953 
primary 'Warshamanage, R.' 6  ?                   
primary 'Yamashita, K.'    7  0000-0002-5442-7582 
primary 'Murshudov, G.'    8  ?                   
primary 'Nureki, O.'       9  0000-0003-1813-7008 
primary 'Murata, T.'       10 0000-0002-5748-4670 
primary 'Kanai, Y.'        11 0000-0001-8126-286X 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man '4F2 cell-surface antigen heavy chain'                  68069.625 1 ? ? ? ? 
2 polymer     man 'Large neutral amino acids transporter small subunit 1' 56043.746 1 ? ? ? ? 
3 non-polymer syn CHOLESTEROL                                             386.654   3 ? ? ? ? 
4 non-polymer syn 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine        760.076   2 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Glycoprotein, 4F2hc,4F2 heavy chain antigen,Lymphocyte activation antigen 4F2 large subunit,Solute carrier family 3 member 2' 
2 
;4F2 light chain,4F2LC,CD98 light chain,Integral membrane protein E16,L-type amino acid transporter 1,hLAT1,Solute carrier family 7 member 5,y+ system cationic amino acid transporter
;
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;GSELQPPEASIAVVSIPRQLPGSHSEAGVQGLSAGDDSELGSHCVAQTGLELLASGDPLPSASQNAEMIETGSDCVTQAG
LQLLASSDPPALASKNAEVTGTMSQDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEKNGLVKIKVAEDEAEAAAAA
KFTGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAG
NLAGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWF
STQVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQILSLLESNKDLL
LTSSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAAL
PGQPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQ
NERFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPYAA
;
;GSELQPPEASIAVVSIPRQLPGSHSEAGVQGLSAGDDSELGSHCVAQTGLELLASGDPLPSASQNAEMIETGSDCVTQAG
LQLLASSDPPALASKNAEVTGTMSQDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEKNGLVKIKVAEDEAEAAAAA
KFTGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAG
NLAGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWF
STQVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQILSLLESNKDLL
LTSSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAAL
PGQPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQ
NERFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPYAA
;
A ? 
2 'polypeptide(L)' no no 
;MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAG
SPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPL
FPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV
GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHL
GVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFF
SFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN
KPKWLLQGIFSTTVLCQKLMQVVPQETDYKDDDDK
;
;MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAG
SPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPL
FPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV
GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHL
GVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFF
SFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN
KPKWLLQGIFSTTVLCQKLMQVVPQETDYKDDDDK
;
B ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 CHOLESTEROL                                      CLR 
4 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine LBN 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   SER n 
1 3   GLU n 
1 4   LEU n 
1 5   GLN n 
1 6   PRO n 
1 7   PRO n 
1 8   GLU n 
1 9   ALA n 
1 10  SER n 
1 11  ILE n 
1 12  ALA n 
1 13  VAL n 
1 14  VAL n 
1 15  SER n 
1 16  ILE n 
1 17  PRO n 
1 18  ARG n 
1 19  GLN n 
1 20  LEU n 
1 21  PRO n 
1 22  GLY n 
1 23  SER n 
1 24  HIS n 
1 25  SER n 
1 26  GLU n 
1 27  ALA n 
1 28  GLY n 
1 29  VAL n 
1 30  GLN n 
1 31  GLY n 
1 32  LEU n 
1 33  SER n 
1 34  ALA n 
1 35  GLY n 
1 36  ASP n 
1 37  ASP n 
1 38  SER n 
1 39  GLU n 
1 40  LEU n 
1 41  GLY n 
1 42  SER n 
1 43  HIS n 
1 44  CYS n 
1 45  VAL n 
1 46  ALA n 
1 47  GLN n 
1 48  THR n 
1 49  GLY n 
1 50  LEU n 
1 51  GLU n 
1 52  LEU n 
1 53  LEU n 
1 54  ALA n 
1 55  SER n 
1 56  GLY n 
1 57  ASP n 
1 58  PRO n 
1 59  LEU n 
1 60  PRO n 
1 61  SER n 
1 62  ALA n 
1 63  SER n 
1 64  GLN n 
1 65  ASN n 
1 66  ALA n 
1 67  GLU n 
1 68  MET n 
1 69  ILE n 
1 70  GLU n 
1 71  THR n 
1 72  GLY n 
1 73  SER n 
1 74  ASP n 
1 75  CYS n 
1 76  VAL n 
1 77  THR n 
1 78  GLN n 
1 79  ALA n 
1 80  GLY n 
1 81  LEU n 
1 82  GLN n 
1 83  LEU n 
1 84  LEU n 
1 85  ALA n 
1 86  SER n 
1 87  SER n 
1 88  ASP n 
1 89  PRO n 
1 90  PRO n 
1 91  ALA n 
1 92  LEU n 
1 93  ALA n 
1 94  SER n 
1 95  LYS n 
1 96  ASN n 
1 97  ALA n 
1 98  GLU n 
1 99  VAL n 
1 100 THR n 
1 101 GLY n 
1 102 THR n 
1 103 MET n 
1 104 SER n 
1 105 GLN n 
1 106 ASP n 
1 107 THR n 
1 108 GLU n 
1 109 VAL n 
1 110 ASP n 
1 111 MET n 
1 112 LYS n 
1 113 GLU n 
1 114 VAL n 
1 115 GLU n 
1 116 LEU n 
1 117 ASN n 
1 118 GLU n 
1 119 LEU n 
1 120 GLU n 
1 121 PRO n 
1 122 GLU n 
1 123 LYS n 
1 124 GLN n 
1 125 PRO n 
1 126 MET n 
1 127 ASN n 
1 128 ALA n 
1 129 ALA n 
1 130 SER n 
1 131 GLY n 
1 132 ALA n 
1 133 ALA n 
1 134 MET n 
1 135 SER n 
1 136 LEU n 
1 137 ALA n 
1 138 GLY n 
1 139 ALA n 
1 140 GLU n 
1 141 LYS n 
1 142 ASN n 
1 143 GLY n 
1 144 LEU n 
1 145 VAL n 
1 146 LYS n 
1 147 ILE n 
1 148 LYS n 
1 149 VAL n 
1 150 ALA n 
1 151 GLU n 
1 152 ASP n 
1 153 GLU n 
1 154 ALA n 
1 155 GLU n 
1 156 ALA n 
1 157 ALA n 
1 158 ALA n 
1 159 ALA n 
1 160 ALA n 
1 161 LYS n 
1 162 PHE n 
1 163 THR n 
1 164 GLY n 
1 165 LEU n 
1 166 SER n 
1 167 LYS n 
1 168 GLU n 
1 169 GLU n 
1 170 LEU n 
1 171 LEU n 
1 172 LYS n 
1 173 VAL n 
1 174 ALA n 
1 175 GLY n 
1 176 SER n 
1 177 PRO n 
1 178 GLY n 
1 179 TRP n 
1 180 VAL n 
1 181 ARG n 
1 182 THR n 
1 183 ARG n 
1 184 TRP n 
1 185 ALA n 
1 186 LEU n 
1 187 LEU n 
1 188 LEU n 
1 189 LEU n 
1 190 PHE n 
1 191 TRP n 
1 192 LEU n 
1 193 GLY n 
1 194 TRP n 
1 195 LEU n 
1 196 GLY n 
1 197 MET n 
1 198 LEU n 
1 199 ALA n 
1 200 GLY n 
1 201 ALA n 
1 202 VAL n 
1 203 VAL n 
1 204 ILE n 
1 205 ILE n 
1 206 VAL n 
1 207 ARG n 
1 208 ALA n 
1 209 PRO n 
1 210 ARG n 
1 211 CYS n 
1 212 ARG n 
1 213 GLU n 
1 214 LEU n 
1 215 PRO n 
1 216 ALA n 
1 217 GLN n 
1 218 LYS n 
1 219 TRP n 
1 220 TRP n 
1 221 HIS n 
1 222 THR n 
1 223 GLY n 
1 224 ALA n 
1 225 LEU n 
1 226 TYR n 
1 227 ARG n 
1 228 ILE n 
1 229 GLY n 
1 230 ASP n 
1 231 LEU n 
1 232 GLN n 
1 233 ALA n 
1 234 PHE n 
1 235 GLN n 
1 236 GLY n 
1 237 HIS n 
1 238 GLY n 
1 239 ALA n 
1 240 GLY n 
1 241 ASN n 
1 242 LEU n 
1 243 ALA n 
1 244 GLY n 
1 245 LEU n 
1 246 LYS n 
1 247 GLY n 
1 248 ARG n 
1 249 LEU n 
1 250 ASP n 
1 251 TYR n 
1 252 LEU n 
1 253 SER n 
1 254 SER n 
1 255 LEU n 
1 256 LYS n 
1 257 VAL n 
1 258 LYS n 
1 259 GLY n 
1 260 LEU n 
1 261 VAL n 
1 262 LEU n 
1 263 GLY n 
1 264 PRO n 
1 265 ILE n 
1 266 HIS n 
1 267 LYS n 
1 268 ASN n 
1 269 GLN n 
1 270 LYS n 
1 271 ASP n 
1 272 ASP n 
1 273 VAL n 
1 274 ALA n 
1 275 GLN n 
1 276 THR n 
1 277 ASP n 
1 278 LEU n 
1 279 LEU n 
1 280 GLN n 
1 281 ILE n 
1 282 ASP n 
1 283 PRO n 
1 284 ASN n 
1 285 PHE n 
1 286 GLY n 
1 287 SER n 
1 288 LYS n 
1 289 GLU n 
1 290 ASP n 
1 291 PHE n 
1 292 ASP n 
1 293 SER n 
1 294 LEU n 
1 295 LEU n 
1 296 GLN n 
1 297 SER n 
1 298 ALA n 
1 299 LYS n 
1 300 LYS n 
1 301 LYS n 
1 302 SER n 
1 303 ILE n 
1 304 ARG n 
1 305 VAL n 
1 306 ILE n 
1 307 LEU n 
1 308 ASP n 
1 309 LEU n 
1 310 THR n 
1 311 PRO n 
1 312 ASN n 
1 313 TYR n 
1 314 ARG n 
1 315 GLY n 
1 316 GLU n 
1 317 ASN n 
1 318 SER n 
1 319 TRP n 
1 320 PHE n 
1 321 SER n 
1 322 THR n 
1 323 GLN n 
1 324 VAL n 
1 325 ASP n 
1 326 THR n 
1 327 VAL n 
1 328 ALA n 
1 329 THR n 
1 330 LYS n 
1 331 VAL n 
1 332 LYS n 
1 333 ASP n 
1 334 ALA n 
1 335 LEU n 
1 336 GLU n 
1 337 PHE n 
1 338 TRP n 
1 339 LEU n 
1 340 GLN n 
1 341 ALA n 
1 342 GLY n 
1 343 VAL n 
1 344 ASP n 
1 345 GLY n 
1 346 PHE n 
1 347 GLN n 
1 348 VAL n 
1 349 ARG n 
1 350 ASP n 
1 351 ILE n 
1 352 GLU n 
1 353 ASN n 
1 354 LEU n 
1 355 LYS n 
1 356 ASP n 
1 357 ALA n 
1 358 SER n 
1 359 SER n 
1 360 PHE n 
1 361 LEU n 
1 362 ALA n 
1 363 GLU n 
1 364 TRP n 
1 365 GLN n 
1 366 ASN n 
1 367 ILE n 
1 368 THR n 
1 369 LYS n 
1 370 GLY n 
1 371 PHE n 
1 372 SER n 
1 373 GLU n 
1 374 ASP n 
1 375 ARG n 
1 376 LEU n 
1 377 LEU n 
1 378 ILE n 
1 379 ALA n 
1 380 GLY n 
1 381 THR n 
1 382 ASN n 
1 383 SER n 
1 384 SER n 
1 385 ASP n 
1 386 LEU n 
1 387 GLN n 
1 388 GLN n 
1 389 ILE n 
1 390 LEU n 
1 391 SER n 
1 392 LEU n 
1 393 LEU n 
1 394 GLU n 
1 395 SER n 
1 396 ASN n 
1 397 LYS n 
1 398 ASP n 
1 399 LEU n 
1 400 LEU n 
1 401 LEU n 
1 402 THR n 
1 403 SER n 
1 404 SER n 
1 405 TYR n 
1 406 LEU n 
1 407 SER n 
1 408 ASP n 
1 409 SER n 
1 410 GLY n 
1 411 SER n 
1 412 THR n 
1 413 GLY n 
1 414 GLU n 
1 415 HIS n 
1 416 THR n 
1 417 LYS n 
1 418 SER n 
1 419 LEU n 
1 420 VAL n 
1 421 THR n 
1 422 GLN n 
1 423 TYR n 
1 424 LEU n 
1 425 ASN n 
1 426 ALA n 
1 427 THR n 
1 428 GLY n 
1 429 ASN n 
1 430 ARG n 
1 431 TRP n 
1 432 CYS n 
1 433 SER n 
1 434 TRP n 
1 435 SER n 
1 436 LEU n 
1 437 SER n 
1 438 GLN n 
1 439 ALA n 
1 440 ARG n 
1 441 LEU n 
1 442 LEU n 
1 443 THR n 
1 444 SER n 
1 445 PHE n 
1 446 LEU n 
1 447 PRO n 
1 448 ALA n 
1 449 GLN n 
1 450 LEU n 
1 451 LEU n 
1 452 ARG n 
1 453 LEU n 
1 454 TYR n 
1 455 GLN n 
1 456 LEU n 
1 457 MET n 
1 458 LEU n 
1 459 PHE n 
1 460 THR n 
1 461 LEU n 
1 462 PRO n 
1 463 GLY n 
1 464 THR n 
1 465 PRO n 
1 466 VAL n 
1 467 PHE n 
1 468 SER n 
1 469 TYR n 
1 470 GLY n 
1 471 ASP n 
1 472 GLU n 
1 473 ILE n 
1 474 GLY n 
1 475 LEU n 
1 476 ASP n 
1 477 ALA n 
1 478 ALA n 
1 479 ALA n 
1 480 LEU n 
1 481 PRO n 
1 482 GLY n 
1 483 GLN n 
1 484 PRO n 
1 485 MET n 
1 486 GLU n 
1 487 ALA n 
1 488 PRO n 
1 489 VAL n 
1 490 MET n 
1 491 LEU n 
1 492 TRP n 
1 493 ASP n 
1 494 GLU n 
1 495 SER n 
1 496 SER n 
1 497 PHE n 
1 498 PRO n 
1 499 ASP n 
1 500 ILE n 
1 501 PRO n 
1 502 GLY n 
1 503 ALA n 
1 504 VAL n 
1 505 SER n 
1 506 ALA n 
1 507 ASN n 
1 508 MET n 
1 509 THR n 
1 510 VAL n 
1 511 LYS n 
1 512 GLY n 
1 513 GLN n 
1 514 SER n 
1 515 GLU n 
1 516 ASP n 
1 517 PRO n 
1 518 GLY n 
1 519 SER n 
1 520 LEU n 
1 521 LEU n 
1 522 SER n 
1 523 LEU n 
1 524 PHE n 
1 525 ARG n 
1 526 ARG n 
1 527 LEU n 
1 528 SER n 
1 529 ASP n 
1 530 GLN n 
1 531 ARG n 
1 532 SER n 
1 533 LYS n 
1 534 GLU n 
1 535 ARG n 
1 536 SER n 
1 537 LEU n 
1 538 LEU n 
1 539 HIS n 
1 540 GLY n 
1 541 ASP n 
1 542 PHE n 
1 543 HIS n 
1 544 ALA n 
1 545 PHE n 
1 546 SER n 
1 547 ALA n 
1 548 GLY n 
1 549 PRO n 
1 550 GLY n 
1 551 LEU n 
1 552 PHE n 
1 553 SER n 
1 554 TYR n 
1 555 ILE n 
1 556 ARG n 
1 557 HIS n 
1 558 TRP n 
1 559 ASP n 
1 560 GLN n 
1 561 ASN n 
1 562 GLU n 
1 563 ARG n 
1 564 PHE n 
1 565 LEU n 
1 566 VAL n 
1 567 VAL n 
1 568 LEU n 
1 569 ASN n 
1 570 PHE n 
1 571 GLY n 
1 572 ASP n 
1 573 VAL n 
1 574 GLY n 
1 575 LEU n 
1 576 SER n 
1 577 ALA n 
1 578 GLY n 
1 579 LEU n 
1 580 GLN n 
1 581 ALA n 
1 582 SER n 
1 583 ASP n 
1 584 LEU n 
1 585 PRO n 
1 586 ALA n 
1 587 SER n 
1 588 ALA n 
1 589 SER n 
1 590 LEU n 
1 591 PRO n 
1 592 ALA n 
1 593 LYS n 
1 594 ALA n 
1 595 ASP n 
1 596 LEU n 
1 597 LEU n 
1 598 LEU n 
1 599 SER n 
1 600 THR n 
1 601 GLN n 
1 602 PRO n 
1 603 GLY n 
1 604 ARG n 
1 605 GLU n 
1 606 GLU n 
1 607 GLY n 
1 608 SER n 
1 609 PRO n 
1 610 LEU n 
1 611 GLU n 
1 612 LEU n 
1 613 GLU n 
1 614 ARG n 
1 615 LEU n 
1 616 LYS n 
1 617 LEU n 
1 618 GLU n 
1 619 PRO n 
1 620 HIS n 
1 621 GLU n 
1 622 GLY n 
1 623 LEU n 
1 624 LEU n 
1 625 LEU n 
1 626 ARG n 
1 627 PHE n 
1 628 PRO n 
1 629 TYR n 
1 630 ALA n 
1 631 ALA n 
2 1   MET n 
2 2   ALA n 
2 3   GLY n 
2 4   ALA n 
2 5   GLY n 
2 6   PRO n 
2 7   LYS n 
2 8   ARG n 
2 9   ARG n 
2 10  ALA n 
2 11  LEU n 
2 12  ALA n 
2 13  ALA n 
2 14  PRO n 
2 15  ALA n 
2 16  ALA n 
2 17  GLU n 
2 18  GLU n 
2 19  LYS n 
2 20  GLU n 
2 21  GLU n 
2 22  ALA n 
2 23  ARG n 
2 24  GLU n 
2 25  LYS n 
2 26  MET n 
2 27  LEU n 
2 28  ALA n 
2 29  ALA n 
2 30  LYS n 
2 31  SER n 
2 32  ALA n 
2 33  ASP n 
2 34  GLY n 
2 35  SER n 
2 36  ALA n 
2 37  PRO n 
2 38  ALA n 
2 39  GLY n 
2 40  GLU n 
2 41  GLY n 
2 42  GLU n 
2 43  GLY n 
2 44  VAL n 
2 45  THR n 
2 46  LEU n 
2 47  GLN n 
2 48  ARG n 
2 49  ASN n 
2 50  ILE n 
2 51  THR n 
2 52  LEU n 
2 53  LEU n 
2 54  ASN n 
2 55  GLY n 
2 56  VAL n 
2 57  ALA n 
2 58  ILE n 
2 59  ILE n 
2 60  VAL n 
2 61  GLY n 
2 62  THR n 
2 63  ILE n 
2 64  ILE n 
2 65  GLY n 
2 66  SER n 
2 67  GLY n 
2 68  ILE n 
2 69  PHE n 
2 70  VAL n 
2 71  THR n 
2 72  PRO n 
2 73  THR n 
2 74  GLY n 
2 75  VAL n 
2 76  LEU n 
2 77  LYS n 
2 78  GLU n 
2 79  ALA n 
2 80  GLY n 
2 81  SER n 
2 82  PRO n 
2 83  GLY n 
2 84  LEU n 
2 85  ALA n 
2 86  LEU n 
2 87  VAL n 
2 88  VAL n 
2 89  TRP n 
2 90  ALA n 
2 91  ALA n 
2 92  CYS n 
2 93  GLY n 
2 94  VAL n 
2 95  PHE n 
2 96  SER n 
2 97  ILE n 
2 98  VAL n 
2 99  GLY n 
2 100 ALA n 
2 101 LEU n 
2 102 CYS n 
2 103 TYR n 
2 104 ALA n 
2 105 GLU n 
2 106 LEU n 
2 107 GLY n 
2 108 THR n 
2 109 THR n 
2 110 ILE n 
2 111 SER n 
2 112 LYS n 
2 113 SER n 
2 114 GLY n 
2 115 GLY n 
2 116 ASP n 
2 117 TYR n 
2 118 ALA n 
2 119 TYR n 
2 120 MET n 
2 121 LEU n 
2 122 GLU n 
2 123 VAL n 
2 124 TYR n 
2 125 GLY n 
2 126 SER n 
2 127 LEU n 
2 128 PRO n 
2 129 ALA n 
2 130 PHE n 
2 131 LEU n 
2 132 LYS n 
2 133 LEU n 
2 134 TRP n 
2 135 ILE n 
2 136 GLU n 
2 137 LEU n 
2 138 LEU n 
2 139 ILE n 
2 140 ILE n 
2 141 ARG n 
2 142 PRO n 
2 143 SER n 
2 144 SER n 
2 145 GLN n 
2 146 TYR n 
2 147 ILE n 
2 148 VAL n 
2 149 ALA n 
2 150 LEU n 
2 151 VAL n 
2 152 PHE n 
2 153 ALA n 
2 154 THR n 
2 155 TYR n 
2 156 LEU n 
2 157 LEU n 
2 158 LYS n 
2 159 PRO n 
2 160 LEU n 
2 161 PHE n 
2 162 PRO n 
2 163 THR n 
2 164 CYS n 
2 165 PRO n 
2 166 VAL n 
2 167 PRO n 
2 168 GLU n 
2 169 GLU n 
2 170 ALA n 
2 171 ALA n 
2 172 LYS n 
2 173 LEU n 
2 174 VAL n 
2 175 ALA n 
2 176 CYS n 
2 177 LEU n 
2 178 CYS n 
2 179 VAL n 
2 180 LEU n 
2 181 LEU n 
2 182 LEU n 
2 183 THR n 
2 184 ALA n 
2 185 VAL n 
2 186 ASN n 
2 187 CYS n 
2 188 TYR n 
2 189 SER n 
2 190 VAL n 
2 191 LYS n 
2 192 ALA n 
2 193 ALA n 
2 194 THR n 
2 195 ARG n 
2 196 VAL n 
2 197 GLN n 
2 198 ASP n 
2 199 ALA n 
2 200 PHE n 
2 201 ALA n 
2 202 ALA n 
2 203 ALA n 
2 204 LYS n 
2 205 LEU n 
2 206 LEU n 
2 207 ALA n 
2 208 LEU n 
2 209 ALA n 
2 210 LEU n 
2 211 ILE n 
2 212 ILE n 
2 213 LEU n 
2 214 LEU n 
2 215 GLY n 
2 216 PHE n 
2 217 VAL n 
2 218 GLN n 
2 219 ILE n 
2 220 GLY n 
2 221 LYS n 
2 222 GLY n 
2 223 ASP n 
2 224 VAL n 
2 225 SER n 
2 226 ASN n 
2 227 LEU n 
2 228 ASP n 
2 229 PRO n 
2 230 ASN n 
2 231 PHE n 
2 232 SER n 
2 233 PHE n 
2 234 GLU n 
2 235 GLY n 
2 236 THR n 
2 237 LYS n 
2 238 LEU n 
2 239 ASP n 
2 240 VAL n 
2 241 GLY n 
2 242 ASN n 
2 243 ILE n 
2 244 VAL n 
2 245 LEU n 
2 246 ALA n 
2 247 LEU n 
2 248 TYR n 
2 249 SER n 
2 250 GLY n 
2 251 LEU n 
2 252 PHE n 
2 253 ALA n 
2 254 TYR n 
2 255 GLY n 
2 256 GLY n 
2 257 TRP n 
2 258 ASN n 
2 259 TYR n 
2 260 LEU n 
2 261 ASN n 
2 262 PHE n 
2 263 VAL n 
2 264 THR n 
2 265 GLU n 
2 266 GLU n 
2 267 MET n 
2 268 ILE n 
2 269 ASN n 
2 270 PRO n 
2 271 TYR n 
2 272 ARG n 
2 273 ASN n 
2 274 LEU n 
2 275 PRO n 
2 276 LEU n 
2 277 ALA n 
2 278 ILE n 
2 279 ILE n 
2 280 ILE n 
2 281 SER n 
2 282 LEU n 
2 283 PRO n 
2 284 ILE n 
2 285 VAL n 
2 286 THR n 
2 287 LEU n 
2 288 VAL n 
2 289 TYR n 
2 290 VAL n 
2 291 LEU n 
2 292 THR n 
2 293 ASN n 
2 294 LEU n 
2 295 ALA n 
2 296 TYR n 
2 297 PHE n 
2 298 THR n 
2 299 THR n 
2 300 LEU n 
2 301 SER n 
2 302 THR n 
2 303 GLU n 
2 304 GLN n 
2 305 MET n 
2 306 LEU n 
2 307 SER n 
2 308 SER n 
2 309 GLU n 
2 310 ALA n 
2 311 VAL n 
2 312 ALA n 
2 313 VAL n 
2 314 ASP n 
2 315 PHE n 
2 316 GLY n 
2 317 ASN n 
2 318 TYR n 
2 319 HIS n 
2 320 LEU n 
2 321 GLY n 
2 322 VAL n 
2 323 MET n 
2 324 SER n 
2 325 TRP n 
2 326 ILE n 
2 327 ILE n 
2 328 PRO n 
2 329 VAL n 
2 330 PHE n 
2 331 VAL n 
2 332 GLY n 
2 333 LEU n 
2 334 SER n 
2 335 CYS n 
2 336 PHE n 
2 337 GLY n 
2 338 SER n 
2 339 VAL n 
2 340 ASN n 
2 341 GLY n 
2 342 SER n 
2 343 LEU n 
2 344 PHE n 
2 345 THR n 
2 346 SER n 
2 347 SER n 
2 348 ARG n 
2 349 LEU n 
2 350 PHE n 
2 351 PHE n 
2 352 VAL n 
2 353 GLY n 
2 354 SER n 
2 355 ARG n 
2 356 GLU n 
2 357 GLY n 
2 358 HIS n 
2 359 LEU n 
2 360 PRO n 
2 361 SER n 
2 362 ILE n 
2 363 LEU n 
2 364 SER n 
2 365 MET n 
2 366 ILE n 
2 367 HIS n 
2 368 PRO n 
2 369 GLN n 
2 370 LEU n 
2 371 LEU n 
2 372 THR n 
2 373 PRO n 
2 374 VAL n 
2 375 PRO n 
2 376 SER n 
2 377 LEU n 
2 378 VAL n 
2 379 PHE n 
2 380 THR n 
2 381 CYS n 
2 382 VAL n 
2 383 MET n 
2 384 THR n 
2 385 LEU n 
2 386 LEU n 
2 387 TYR n 
2 388 ALA n 
2 389 PHE n 
2 390 SER n 
2 391 LYS n 
2 392 ASP n 
2 393 ILE n 
2 394 PHE n 
2 395 SER n 
2 396 VAL n 
2 397 ILE n 
2 398 ASN n 
2 399 PHE n 
2 400 PHE n 
2 401 SER n 
2 402 PHE n 
2 403 PHE n 
2 404 ASN n 
2 405 TRP n 
2 406 LEU n 
2 407 CYS n 
2 408 VAL n 
2 409 ALA n 
2 410 LEU n 
2 411 ALA n 
2 412 ILE n 
2 413 ILE n 
2 414 GLY n 
2 415 MET n 
2 416 ILE n 
2 417 TRP n 
2 418 LEU n 
2 419 ARG n 
2 420 HIS n 
2 421 ARG n 
2 422 LYS n 
2 423 PRO n 
2 424 GLU n 
2 425 LEU n 
2 426 GLU n 
2 427 ARG n 
2 428 PRO n 
2 429 ILE n 
2 430 LYS n 
2 431 VAL n 
2 432 ASN n 
2 433 LEU n 
2 434 ALA n 
2 435 LEU n 
2 436 PRO n 
2 437 VAL n 
2 438 PHE n 
2 439 PHE n 
2 440 ILE n 
2 441 LEU n 
2 442 ALA n 
2 443 CYS n 
2 444 LEU n 
2 445 PHE n 
2 446 LEU n 
2 447 ILE n 
2 448 ALA n 
2 449 VAL n 
2 450 SER n 
2 451 PHE n 
2 452 TRP n 
2 453 LYS n 
2 454 THR n 
2 455 PRO n 
2 456 VAL n 
2 457 GLU n 
2 458 CYS n 
2 459 GLY n 
2 460 ILE n 
2 461 GLY n 
2 462 PHE n 
2 463 THR n 
2 464 ILE n 
2 465 ILE n 
2 466 LEU n 
2 467 SER n 
2 468 GLY n 
2 469 LEU n 
2 470 PRO n 
2 471 VAL n 
2 472 TYR n 
2 473 PHE n 
2 474 PHE n 
2 475 GLY n 
2 476 VAL n 
2 477 TRP n 
2 478 TRP n 
2 479 LYS n 
2 480 ASN n 
2 481 LYS n 
2 482 PRO n 
2 483 LYS n 
2 484 TRP n 
2 485 LEU n 
2 486 LEU n 
2 487 GLN n 
2 488 GLY n 
2 489 ILE n 
2 490 PHE n 
2 491 SER n 
2 492 THR n 
2 493 THR n 
2 494 VAL n 
2 495 LEU n 
2 496 CYS n 
2 497 GLN n 
2 498 LYS n 
2 499 LEU n 
2 500 MET n 
2 501 GLN n 
2 502 VAL n 
2 503 VAL n 
2 504 PRO n 
2 505 GLN n 
2 506 GLU n 
2 507 THR n 
2 508 ASP n 
2 509 TYR n 
2 510 LYS n 
2 511 ASP n 
2 512 ASP n 
2 513 ASP n 
2 514 ASP n 
2 515 LYS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 631 human ? 'SLC3A2, MDU1'                ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 515 human ? 'SLC7A5, CD98LC, LAT1, MPE16' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                          ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                                         ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                                       ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                  ? 'C4 H7 N O4'     133.103 
CLR non-polymer         . CHOLESTEROL                                      ? 'C27 H46 O'      386.654 
CYS 'L-peptide linking' y CYSTEINE                                         ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                                        ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                  ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                          ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                                        ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE                                       ? 'C6 H13 N O2'    131.173 
LBN non-polymer         . 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine 
'(2R)-2-[(9Z)-9-Octadecenoyloxy]-3-(palmitoyloxy)propyl 2-(trimethylammonio)ethyl phosphate' 'C42 H82 N O8 P' 760.076 
LEU 'L-peptide linking' y LEUCINE                                          ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                           ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                                       ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                    ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                                          ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                           ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                                        ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                       ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                         ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                           ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   0   ?   ?   ?   A . n 
A 1 2   SER 2   1   ?   ?   ?   A . n 
A 1 3   GLU 3   2   ?   ?   ?   A . n 
A 1 4   LEU 4   3   ?   ?   ?   A . n 
A 1 5   GLN 5   4   ?   ?   ?   A . n 
A 1 6   PRO 6   5   ?   ?   ?   A . n 
A 1 7   PRO 7   6   ?   ?   ?   A . n 
A 1 8   GLU 8   7   ?   ?   ?   A . n 
A 1 9   ALA 9   8   ?   ?   ?   A . n 
A 1 10  SER 10  9   ?   ?   ?   A . n 
A 1 11  ILE 11  10  ?   ?   ?   A . n 
A 1 12  ALA 12  11  ?   ?   ?   A . n 
A 1 13  VAL 13  12  ?   ?   ?   A . n 
A 1 14  VAL 14  13  ?   ?   ?   A . n 
A 1 15  SER 15  14  ?   ?   ?   A . n 
A 1 16  ILE 16  15  ?   ?   ?   A . n 
A 1 17  PRO 17  16  ?   ?   ?   A . n 
A 1 18  ARG 18  17  ?   ?   ?   A . n 
A 1 19  GLN 19  18  ?   ?   ?   A . n 
A 1 20  LEU 20  19  ?   ?   ?   A . n 
A 1 21  PRO 21  20  ?   ?   ?   A . n 
A 1 22  GLY 22  21  ?   ?   ?   A . n 
A 1 23  SER 23  22  ?   ?   ?   A . n 
A 1 24  HIS 24  23  ?   ?   ?   A . n 
A 1 25  SER 25  24  ?   ?   ?   A . n 
A 1 26  GLU 26  25  ?   ?   ?   A . n 
A 1 27  ALA 27  26  ?   ?   ?   A . n 
A 1 28  GLY 28  27  ?   ?   ?   A . n 
A 1 29  VAL 29  28  ?   ?   ?   A . n 
A 1 30  GLN 30  29  ?   ?   ?   A . n 
A 1 31  GLY 31  30  ?   ?   ?   A . n 
A 1 32  LEU 32  31  ?   ?   ?   A . n 
A 1 33  SER 33  32  ?   ?   ?   A . n 
A 1 34  ALA 34  33  ?   ?   ?   A . n 
A 1 35  GLY 35  34  ?   ?   ?   A . n 
A 1 36  ASP 36  35  ?   ?   ?   A . n 
A 1 37  ASP 37  36  ?   ?   ?   A . n 
A 1 38  SER 38  37  ?   ?   ?   A . n 
A 1 39  GLU 39  38  ?   ?   ?   A . n 
A 1 40  LEU 40  39  ?   ?   ?   A . n 
A 1 41  GLY 41  40  ?   ?   ?   A . n 
A 1 42  SER 42  41  ?   ?   ?   A . n 
A 1 43  HIS 43  42  ?   ?   ?   A . n 
A 1 44  CYS 44  43  ?   ?   ?   A . n 
A 1 45  VAL 45  44  ?   ?   ?   A . n 
A 1 46  ALA 46  45  ?   ?   ?   A . n 
A 1 47  GLN 47  46  ?   ?   ?   A . n 
A 1 48  THR 48  47  ?   ?   ?   A . n 
A 1 49  GLY 49  48  ?   ?   ?   A . n 
A 1 50  LEU 50  49  ?   ?   ?   A . n 
A 1 51  GLU 51  50  ?   ?   ?   A . n 
A 1 52  LEU 52  51  ?   ?   ?   A . n 
A 1 53  LEU 53  52  ?   ?   ?   A . n 
A 1 54  ALA 54  53  ?   ?   ?   A . n 
A 1 55  SER 55  54  ?   ?   ?   A . n 
A 1 56  GLY 56  55  ?   ?   ?   A . n 
A 1 57  ASP 57  56  ?   ?   ?   A . n 
A 1 58  PRO 58  57  ?   ?   ?   A . n 
A 1 59  LEU 59  58  ?   ?   ?   A . n 
A 1 60  PRO 60  59  ?   ?   ?   A . n 
A 1 61  SER 61  60  ?   ?   ?   A . n 
A 1 62  ALA 62  61  ?   ?   ?   A . n 
A 1 63  SER 63  62  ?   ?   ?   A . n 
A 1 64  GLN 64  63  ?   ?   ?   A . n 
A 1 65  ASN 65  64  ?   ?   ?   A . n 
A 1 66  ALA 66  65  ?   ?   ?   A . n 
A 1 67  GLU 67  66  ?   ?   ?   A . n 
A 1 68  MET 68  67  ?   ?   ?   A . n 
A 1 69  ILE 69  68  ?   ?   ?   A . n 
A 1 70  GLU 70  69  ?   ?   ?   A . n 
A 1 71  THR 71  70  ?   ?   ?   A . n 
A 1 72  GLY 72  71  ?   ?   ?   A . n 
A 1 73  SER 73  72  ?   ?   ?   A . n 
A 1 74  ASP 74  73  ?   ?   ?   A . n 
A 1 75  CYS 75  74  ?   ?   ?   A . n 
A 1 76  VAL 76  75  ?   ?   ?   A . n 
A 1 77  THR 77  76  ?   ?   ?   A . n 
A 1 78  GLN 78  77  ?   ?   ?   A . n 
A 1 79  ALA 79  78  ?   ?   ?   A . n 
A 1 80  GLY 80  79  ?   ?   ?   A . n 
A 1 81  LEU 81  80  ?   ?   ?   A . n 
A 1 82  GLN 82  81  ?   ?   ?   A . n 
A 1 83  LEU 83  82  ?   ?   ?   A . n 
A 1 84  LEU 84  83  ?   ?   ?   A . n 
A 1 85  ALA 85  84  ?   ?   ?   A . n 
A 1 86  SER 86  85  ?   ?   ?   A . n 
A 1 87  SER 87  86  ?   ?   ?   A . n 
A 1 88  ASP 88  87  ?   ?   ?   A . n 
A 1 89  PRO 89  88  ?   ?   ?   A . n 
A 1 90  PRO 90  89  ?   ?   ?   A . n 
A 1 91  ALA 91  90  ?   ?   ?   A . n 
A 1 92  LEU 92  91  ?   ?   ?   A . n 
A 1 93  ALA 93  92  ?   ?   ?   A . n 
A 1 94  SER 94  93  ?   ?   ?   A . n 
A 1 95  LYS 95  94  ?   ?   ?   A . n 
A 1 96  ASN 96  95  ?   ?   ?   A . n 
A 1 97  ALA 97  96  ?   ?   ?   A . n 
A 1 98  GLU 98  97  ?   ?   ?   A . n 
A 1 99  VAL 99  98  ?   ?   ?   A . n 
A 1 100 THR 100 99  ?   ?   ?   A . n 
A 1 101 GLY 101 100 ?   ?   ?   A . n 
A 1 102 THR 102 101 ?   ?   ?   A . n 
A 1 103 MET 103 102 ?   ?   ?   A . n 
A 1 104 SER 104 103 ?   ?   ?   A . n 
A 1 105 GLN 105 104 ?   ?   ?   A . n 
A 1 106 ASP 106 105 ?   ?   ?   A . n 
A 1 107 THR 107 106 ?   ?   ?   A . n 
A 1 108 GLU 108 107 ?   ?   ?   A . n 
A 1 109 VAL 109 108 ?   ?   ?   A . n 
A 1 110 ASP 110 109 ?   ?   ?   A . n 
A 1 111 MET 111 110 ?   ?   ?   A . n 
A 1 112 LYS 112 111 ?   ?   ?   A . n 
A 1 113 GLU 113 112 ?   ?   ?   A . n 
A 1 114 VAL 114 113 ?   ?   ?   A . n 
A 1 115 GLU 115 114 ?   ?   ?   A . n 
A 1 116 LEU 116 115 ?   ?   ?   A . n 
A 1 117 ASN 117 116 ?   ?   ?   A . n 
A 1 118 GLU 118 117 ?   ?   ?   A . n 
A 1 119 LEU 119 118 ?   ?   ?   A . n 
A 1 120 GLU 120 119 ?   ?   ?   A . n 
A 1 121 PRO 121 120 ?   ?   ?   A . n 
A 1 122 GLU 122 121 ?   ?   ?   A . n 
A 1 123 LYS 123 122 ?   ?   ?   A . n 
A 1 124 GLN 124 123 ?   ?   ?   A . n 
A 1 125 PRO 125 124 ?   ?   ?   A . n 
A 1 126 MET 126 125 ?   ?   ?   A . n 
A 1 127 ASN 127 126 ?   ?   ?   A . n 
A 1 128 ALA 128 127 ?   ?   ?   A . n 
A 1 129 ALA 129 128 ?   ?   ?   A . n 
A 1 130 SER 130 129 ?   ?   ?   A . n 
A 1 131 GLY 131 130 ?   ?   ?   A . n 
A 1 132 ALA 132 131 ?   ?   ?   A . n 
A 1 133 ALA 133 132 ?   ?   ?   A . n 
A 1 134 MET 134 133 ?   ?   ?   A . n 
A 1 135 SER 135 134 ?   ?   ?   A . n 
A 1 136 LEU 136 135 ?   ?   ?   A . n 
A 1 137 ALA 137 136 ?   ?   ?   A . n 
A 1 138 GLY 138 137 ?   ?   ?   A . n 
A 1 139 ALA 139 138 ?   ?   ?   A . n 
A 1 140 GLU 140 139 ?   ?   ?   A . n 
A 1 141 LYS 141 140 ?   ?   ?   A . n 
A 1 142 ASN 142 141 ?   ?   ?   A . n 
A 1 143 GLY 143 142 ?   ?   ?   A . n 
A 1 144 LEU 144 143 ?   ?   ?   A . n 
A 1 145 VAL 145 144 ?   ?   ?   A . n 
A 1 146 LYS 146 145 ?   ?   ?   A . n 
A 1 147 ILE 147 146 ?   ?   ?   A . n 
A 1 148 LYS 148 147 ?   ?   ?   A . n 
A 1 149 VAL 149 148 ?   ?   ?   A . n 
A 1 150 ALA 150 149 ?   ?   ?   A . n 
A 1 151 GLU 151 150 ?   ?   ?   A . n 
A 1 152 ASP 152 151 ?   ?   ?   A . n 
A 1 153 GLU 153 152 ?   ?   ?   A . n 
A 1 154 ALA 154 153 ?   ?   ?   A . n 
A 1 155 GLU 155 154 ?   ?   ?   A . n 
A 1 156 ALA 156 155 ?   ?   ?   A . n 
A 1 157 ALA 157 156 ?   ?   ?   A . n 
A 1 158 ALA 158 157 ?   ?   ?   A . n 
A 1 159 ALA 159 158 ?   ?   ?   A . n 
A 1 160 ALA 160 159 ?   ?   ?   A . n 
A 1 161 LYS 161 160 ?   ?   ?   A . n 
A 1 162 PHE 162 161 ?   ?   ?   A . n 
A 1 163 THR 163 162 162 THR THR A . n 
A 1 164 GLY 164 163 163 GLY GLY A . n 
A 1 165 LEU 165 164 164 LEU LEU A . n 
A 1 166 SER 166 165 165 SER SER A . n 
A 1 167 LYS 167 166 166 LYS LYS A . n 
A 1 168 GLU 168 167 167 GLU GLU A . n 
A 1 169 GLU 169 168 168 GLU GLU A . n 
A 1 170 LEU 170 169 169 LEU LEU A . n 
A 1 171 LEU 171 170 170 LEU LEU A . n 
A 1 172 LYS 172 171 171 LYS LYS A . n 
A 1 173 VAL 173 172 172 VAL VAL A . n 
A 1 174 ALA 174 173 173 ALA ALA A . n 
A 1 175 GLY 175 174 174 GLY GLY A . n 
A 1 176 SER 176 175 175 SER SER A . n 
A 1 177 PRO 177 176 176 PRO PRO A . n 
A 1 178 GLY 178 177 177 GLY GLY A . n 
A 1 179 TRP 179 178 178 TRP TRP A . n 
A 1 180 VAL 180 179 179 VAL VAL A . n 
A 1 181 ARG 181 180 180 ARG ARG A . n 
A 1 182 THR 182 181 181 THR THR A . n 
A 1 183 ARG 183 182 182 ARG ARG A . n 
A 1 184 TRP 184 183 183 TRP TRP A . n 
A 1 185 ALA 185 184 184 ALA ALA A . n 
A 1 186 LEU 186 185 185 LEU LEU A . n 
A 1 187 LEU 187 186 186 LEU LEU A . n 
A 1 188 LEU 188 187 187 LEU LEU A . n 
A 1 189 LEU 189 188 188 LEU LEU A . n 
A 1 190 PHE 190 189 189 PHE PHE A . n 
A 1 191 TRP 191 190 190 TRP TRP A . n 
A 1 192 LEU 192 191 191 LEU LEU A . n 
A 1 193 GLY 193 192 192 GLY GLY A . n 
A 1 194 TRP 194 193 193 TRP TRP A . n 
A 1 195 LEU 195 194 194 LEU LEU A . n 
A 1 196 GLY 196 195 195 GLY GLY A . n 
A 1 197 MET 197 196 196 MET MET A . n 
A 1 198 LEU 198 197 197 LEU LEU A . n 
A 1 199 ALA 199 198 198 ALA ALA A . n 
A 1 200 GLY 200 199 199 GLY GLY A . n 
A 1 201 ALA 201 200 200 ALA ALA A . n 
A 1 202 VAL 202 201 201 VAL VAL A . n 
A 1 203 VAL 203 202 202 VAL VAL A . n 
A 1 204 ILE 204 203 203 ILE ILE A . n 
A 1 205 ILE 205 204 204 ILE ILE A . n 
A 1 206 VAL 206 205 205 VAL VAL A . n 
A 1 207 ARG 207 206 206 ARG ARG A . n 
A 1 208 ALA 208 207 207 ALA ALA A . n 
A 1 209 PRO 209 208 208 PRO PRO A . n 
A 1 210 ARG 210 209 209 ARG ARG A . n 
A 1 211 CYS 211 210 210 CYS CYS A . n 
A 1 212 ARG 212 211 211 ARG ARG A . n 
A 1 213 GLU 213 212 212 GLU GLU A . n 
A 1 214 LEU 214 213 213 LEU LEU A . n 
A 1 215 PRO 215 214 ?   ?   ?   A . n 
A 1 216 ALA 216 215 ?   ?   ?   A . n 
A 1 217 GLN 217 216 ?   ?   ?   A . n 
A 1 218 LYS 218 217 ?   ?   ?   A . n 
A 1 219 TRP 219 218 ?   ?   ?   A . n 
A 1 220 TRP 220 219 ?   ?   ?   A . n 
A 1 221 HIS 221 220 ?   ?   ?   A . n 
A 1 222 THR 222 221 ?   ?   ?   A . n 
A 1 223 GLY 223 222 ?   ?   ?   A . n 
A 1 224 ALA 224 223 ?   ?   ?   A . n 
A 1 225 LEU 225 224 ?   ?   ?   A . n 
A 1 226 TYR 226 225 ?   ?   ?   A . n 
A 1 227 ARG 227 226 ?   ?   ?   A . n 
A 1 228 ILE 228 227 ?   ?   ?   A . n 
A 1 229 GLY 229 228 ?   ?   ?   A . n 
A 1 230 ASP 230 229 ?   ?   ?   A . n 
A 1 231 LEU 231 230 ?   ?   ?   A . n 
A 1 232 GLN 232 231 ?   ?   ?   A . n 
A 1 233 ALA 233 232 ?   ?   ?   A . n 
A 1 234 PHE 234 233 ?   ?   ?   A . n 
A 1 235 GLN 235 234 ?   ?   ?   A . n 
A 1 236 GLY 236 235 ?   ?   ?   A . n 
A 1 237 HIS 237 236 ?   ?   ?   A . n 
A 1 238 GLY 238 237 ?   ?   ?   A . n 
A 1 239 ALA 239 238 ?   ?   ?   A . n 
A 1 240 GLY 240 239 ?   ?   ?   A . n 
A 1 241 ASN 241 240 ?   ?   ?   A . n 
A 1 242 LEU 242 241 ?   ?   ?   A . n 
A 1 243 ALA 243 242 ?   ?   ?   A . n 
A 1 244 GLY 244 243 ?   ?   ?   A . n 
A 1 245 LEU 245 244 ?   ?   ?   A . n 
A 1 246 LYS 246 245 ?   ?   ?   A . n 
A 1 247 GLY 247 246 ?   ?   ?   A . n 
A 1 248 ARG 248 247 ?   ?   ?   A . n 
A 1 249 LEU 249 248 ?   ?   ?   A . n 
A 1 250 ASP 250 249 ?   ?   ?   A . n 
A 1 251 TYR 251 250 ?   ?   ?   A . n 
A 1 252 LEU 252 251 ?   ?   ?   A . n 
A 1 253 SER 253 252 ?   ?   ?   A . n 
A 1 254 SER 254 253 ?   ?   ?   A . n 
A 1 255 LEU 255 254 ?   ?   ?   A . n 
A 1 256 LYS 256 255 ?   ?   ?   A . n 
A 1 257 VAL 257 256 ?   ?   ?   A . n 
A 1 258 LYS 258 257 ?   ?   ?   A . n 
A 1 259 GLY 259 258 ?   ?   ?   A . n 
A 1 260 LEU 260 259 ?   ?   ?   A . n 
A 1 261 VAL 261 260 ?   ?   ?   A . n 
A 1 262 LEU 262 261 ?   ?   ?   A . n 
A 1 263 GLY 263 262 ?   ?   ?   A . n 
A 1 264 PRO 264 263 ?   ?   ?   A . n 
A 1 265 ILE 265 264 ?   ?   ?   A . n 
A 1 266 HIS 266 265 ?   ?   ?   A . n 
A 1 267 LYS 267 266 ?   ?   ?   A . n 
A 1 268 ASN 268 267 ?   ?   ?   A . n 
A 1 269 GLN 269 268 ?   ?   ?   A . n 
A 1 270 LYS 270 269 ?   ?   ?   A . n 
A 1 271 ASP 271 270 ?   ?   ?   A . n 
A 1 272 ASP 272 271 ?   ?   ?   A . n 
A 1 273 VAL 273 272 ?   ?   ?   A . n 
A 1 274 ALA 274 273 ?   ?   ?   A . n 
A 1 275 GLN 275 274 ?   ?   ?   A . n 
A 1 276 THR 276 275 ?   ?   ?   A . n 
A 1 277 ASP 277 276 ?   ?   ?   A . n 
A 1 278 LEU 278 277 ?   ?   ?   A . n 
A 1 279 LEU 279 278 ?   ?   ?   A . n 
A 1 280 GLN 280 279 ?   ?   ?   A . n 
A 1 281 ILE 281 280 ?   ?   ?   A . n 
A 1 282 ASP 282 281 ?   ?   ?   A . n 
A 1 283 PRO 283 282 ?   ?   ?   A . n 
A 1 284 ASN 284 283 ?   ?   ?   A . n 
A 1 285 PHE 285 284 ?   ?   ?   A . n 
A 1 286 GLY 286 285 ?   ?   ?   A . n 
A 1 287 SER 287 286 ?   ?   ?   A . n 
A 1 288 LYS 288 287 ?   ?   ?   A . n 
A 1 289 GLU 289 288 ?   ?   ?   A . n 
A 1 290 ASP 290 289 ?   ?   ?   A . n 
A 1 291 PHE 291 290 ?   ?   ?   A . n 
A 1 292 ASP 292 291 ?   ?   ?   A . n 
A 1 293 SER 293 292 ?   ?   ?   A . n 
A 1 294 LEU 294 293 ?   ?   ?   A . n 
A 1 295 LEU 295 294 ?   ?   ?   A . n 
A 1 296 GLN 296 295 ?   ?   ?   A . n 
A 1 297 SER 297 296 ?   ?   ?   A . n 
A 1 298 ALA 298 297 ?   ?   ?   A . n 
A 1 299 LYS 299 298 ?   ?   ?   A . n 
A 1 300 LYS 300 299 ?   ?   ?   A . n 
A 1 301 LYS 301 300 ?   ?   ?   A . n 
A 1 302 SER 302 301 ?   ?   ?   A . n 
A 1 303 ILE 303 302 ?   ?   ?   A . n 
A 1 304 ARG 304 303 ?   ?   ?   A . n 
A 1 305 VAL 305 304 ?   ?   ?   A . n 
A 1 306 ILE 306 305 ?   ?   ?   A . n 
A 1 307 LEU 307 306 ?   ?   ?   A . n 
A 1 308 ASP 308 307 ?   ?   ?   A . n 
A 1 309 LEU 309 308 ?   ?   ?   A . n 
A 1 310 THR 310 309 ?   ?   ?   A . n 
A 1 311 PRO 311 310 ?   ?   ?   A . n 
A 1 312 ASN 312 311 ?   ?   ?   A . n 
A 1 313 TYR 313 312 ?   ?   ?   A . n 
A 1 314 ARG 314 313 ?   ?   ?   A . n 
A 1 315 GLY 315 314 ?   ?   ?   A . n 
A 1 316 GLU 316 315 ?   ?   ?   A . n 
A 1 317 ASN 317 316 ?   ?   ?   A . n 
A 1 318 SER 318 317 ?   ?   ?   A . n 
A 1 319 TRP 319 318 ?   ?   ?   A . n 
A 1 320 PHE 320 319 ?   ?   ?   A . n 
A 1 321 SER 321 320 ?   ?   ?   A . n 
A 1 322 THR 322 321 ?   ?   ?   A . n 
A 1 323 GLN 323 322 ?   ?   ?   A . n 
A 1 324 VAL 324 323 ?   ?   ?   A . n 
A 1 325 ASP 325 324 ?   ?   ?   A . n 
A 1 326 THR 326 325 ?   ?   ?   A . n 
A 1 327 VAL 327 326 ?   ?   ?   A . n 
A 1 328 ALA 328 327 ?   ?   ?   A . n 
A 1 329 THR 329 328 ?   ?   ?   A . n 
A 1 330 LYS 330 329 ?   ?   ?   A . n 
A 1 331 VAL 331 330 ?   ?   ?   A . n 
A 1 332 LYS 332 331 ?   ?   ?   A . n 
A 1 333 ASP 333 332 ?   ?   ?   A . n 
A 1 334 ALA 334 333 ?   ?   ?   A . n 
A 1 335 LEU 335 334 ?   ?   ?   A . n 
A 1 336 GLU 336 335 ?   ?   ?   A . n 
A 1 337 PHE 337 336 ?   ?   ?   A . n 
A 1 338 TRP 338 337 ?   ?   ?   A . n 
A 1 339 LEU 339 338 ?   ?   ?   A . n 
A 1 340 GLN 340 339 ?   ?   ?   A . n 
A 1 341 ALA 341 340 ?   ?   ?   A . n 
A 1 342 GLY 342 341 ?   ?   ?   A . n 
A 1 343 VAL 343 342 ?   ?   ?   A . n 
A 1 344 ASP 344 343 ?   ?   ?   A . n 
A 1 345 GLY 345 344 ?   ?   ?   A . n 
A 1 346 PHE 346 345 ?   ?   ?   A . n 
A 1 347 GLN 347 346 ?   ?   ?   A . n 
A 1 348 VAL 348 347 ?   ?   ?   A . n 
A 1 349 ARG 349 348 ?   ?   ?   A . n 
A 1 350 ASP 350 349 ?   ?   ?   A . n 
A 1 351 ILE 351 350 ?   ?   ?   A . n 
A 1 352 GLU 352 351 ?   ?   ?   A . n 
A 1 353 ASN 353 352 ?   ?   ?   A . n 
A 1 354 LEU 354 353 ?   ?   ?   A . n 
A 1 355 LYS 355 354 ?   ?   ?   A . n 
A 1 356 ASP 356 355 ?   ?   ?   A . n 
A 1 357 ALA 357 356 ?   ?   ?   A . n 
A 1 358 SER 358 357 ?   ?   ?   A . n 
A 1 359 SER 359 358 ?   ?   ?   A . n 
A 1 360 PHE 360 359 ?   ?   ?   A . n 
A 1 361 LEU 361 360 ?   ?   ?   A . n 
A 1 362 ALA 362 361 ?   ?   ?   A . n 
A 1 363 GLU 363 362 ?   ?   ?   A . n 
A 1 364 TRP 364 363 ?   ?   ?   A . n 
A 1 365 GLN 365 364 ?   ?   ?   A . n 
A 1 366 ASN 366 365 ?   ?   ?   A . n 
A 1 367 ILE 367 366 ?   ?   ?   A . n 
A 1 368 THR 368 367 ?   ?   ?   A . n 
A 1 369 LYS 369 368 ?   ?   ?   A . n 
A 1 370 GLY 370 369 ?   ?   ?   A . n 
A 1 371 PHE 371 370 ?   ?   ?   A . n 
A 1 372 SER 372 371 ?   ?   ?   A . n 
A 1 373 GLU 373 372 ?   ?   ?   A . n 
A 1 374 ASP 374 373 ?   ?   ?   A . n 
A 1 375 ARG 375 374 ?   ?   ?   A . n 
A 1 376 LEU 376 375 ?   ?   ?   A . n 
A 1 377 LEU 377 376 ?   ?   ?   A . n 
A 1 378 ILE 378 377 ?   ?   ?   A . n 
A 1 379 ALA 379 378 ?   ?   ?   A . n 
A 1 380 GLY 380 379 ?   ?   ?   A . n 
A 1 381 THR 381 380 ?   ?   ?   A . n 
A 1 382 ASN 382 381 ?   ?   ?   A . n 
A 1 383 SER 383 382 ?   ?   ?   A . n 
A 1 384 SER 384 383 ?   ?   ?   A . n 
A 1 385 ASP 385 384 ?   ?   ?   A . n 
A 1 386 LEU 386 385 ?   ?   ?   A . n 
A 1 387 GLN 387 386 ?   ?   ?   A . n 
A 1 388 GLN 388 387 ?   ?   ?   A . n 
A 1 389 ILE 389 388 ?   ?   ?   A . n 
A 1 390 LEU 390 389 ?   ?   ?   A . n 
A 1 391 SER 391 390 ?   ?   ?   A . n 
A 1 392 LEU 392 391 ?   ?   ?   A . n 
A 1 393 LEU 393 392 ?   ?   ?   A . n 
A 1 394 GLU 394 393 ?   ?   ?   A . n 
A 1 395 SER 395 394 ?   ?   ?   A . n 
A 1 396 ASN 396 395 ?   ?   ?   A . n 
A 1 397 LYS 397 396 ?   ?   ?   A . n 
A 1 398 ASP 398 397 ?   ?   ?   A . n 
A 1 399 LEU 399 398 ?   ?   ?   A . n 
A 1 400 LEU 400 399 ?   ?   ?   A . n 
A 1 401 LEU 401 400 ?   ?   ?   A . n 
A 1 402 THR 402 401 ?   ?   ?   A . n 
A 1 403 SER 403 402 ?   ?   ?   A . n 
A 1 404 SER 404 403 ?   ?   ?   A . n 
A 1 405 TYR 405 404 ?   ?   ?   A . n 
A 1 406 LEU 406 405 ?   ?   ?   A . n 
A 1 407 SER 407 406 ?   ?   ?   A . n 
A 1 408 ASP 408 407 ?   ?   ?   A . n 
A 1 409 SER 409 408 ?   ?   ?   A . n 
A 1 410 GLY 410 409 ?   ?   ?   A . n 
A 1 411 SER 411 410 ?   ?   ?   A . n 
A 1 412 THR 412 411 ?   ?   ?   A . n 
A 1 413 GLY 413 412 ?   ?   ?   A . n 
A 1 414 GLU 414 413 ?   ?   ?   A . n 
A 1 415 HIS 415 414 ?   ?   ?   A . n 
A 1 416 THR 416 415 ?   ?   ?   A . n 
A 1 417 LYS 417 416 ?   ?   ?   A . n 
A 1 418 SER 418 417 ?   ?   ?   A . n 
A 1 419 LEU 419 418 ?   ?   ?   A . n 
A 1 420 VAL 420 419 ?   ?   ?   A . n 
A 1 421 THR 421 420 ?   ?   ?   A . n 
A 1 422 GLN 422 421 ?   ?   ?   A . n 
A 1 423 TYR 423 422 ?   ?   ?   A . n 
A 1 424 LEU 424 423 ?   ?   ?   A . n 
A 1 425 ASN 425 424 ?   ?   ?   A . n 
A 1 426 ALA 426 425 ?   ?   ?   A . n 
A 1 427 THR 427 426 ?   ?   ?   A . n 
A 1 428 GLY 428 427 ?   ?   ?   A . n 
A 1 429 ASN 429 428 ?   ?   ?   A . n 
A 1 430 ARG 430 429 ?   ?   ?   A . n 
A 1 431 TRP 431 430 ?   ?   ?   A . n 
A 1 432 CYS 432 431 ?   ?   ?   A . n 
A 1 433 SER 433 432 ?   ?   ?   A . n 
A 1 434 TRP 434 433 ?   ?   ?   A . n 
A 1 435 SER 435 434 ?   ?   ?   A . n 
A 1 436 LEU 436 435 ?   ?   ?   A . n 
A 1 437 SER 437 436 ?   ?   ?   A . n 
A 1 438 GLN 438 437 ?   ?   ?   A . n 
A 1 439 ALA 439 438 ?   ?   ?   A . n 
A 1 440 ARG 440 439 ?   ?   ?   A . n 
A 1 441 LEU 441 440 ?   ?   ?   A . n 
A 1 442 LEU 442 441 ?   ?   ?   A . n 
A 1 443 THR 443 442 ?   ?   ?   A . n 
A 1 444 SER 444 443 ?   ?   ?   A . n 
A 1 445 PHE 445 444 ?   ?   ?   A . n 
A 1 446 LEU 446 445 ?   ?   ?   A . n 
A 1 447 PRO 447 446 ?   ?   ?   A . n 
A 1 448 ALA 448 447 ?   ?   ?   A . n 
A 1 449 GLN 449 448 ?   ?   ?   A . n 
A 1 450 LEU 450 449 ?   ?   ?   A . n 
A 1 451 LEU 451 450 ?   ?   ?   A . n 
A 1 452 ARG 452 451 ?   ?   ?   A . n 
A 1 453 LEU 453 452 ?   ?   ?   A . n 
A 1 454 TYR 454 453 ?   ?   ?   A . n 
A 1 455 GLN 455 454 ?   ?   ?   A . n 
A 1 456 LEU 456 455 ?   ?   ?   A . n 
A 1 457 MET 457 456 ?   ?   ?   A . n 
A 1 458 LEU 458 457 ?   ?   ?   A . n 
A 1 459 PHE 459 458 ?   ?   ?   A . n 
A 1 460 THR 460 459 ?   ?   ?   A . n 
A 1 461 LEU 461 460 ?   ?   ?   A . n 
A 1 462 PRO 462 461 ?   ?   ?   A . n 
A 1 463 GLY 463 462 ?   ?   ?   A . n 
A 1 464 THR 464 463 ?   ?   ?   A . n 
A 1 465 PRO 465 464 ?   ?   ?   A . n 
A 1 466 VAL 466 465 ?   ?   ?   A . n 
A 1 467 PHE 467 466 ?   ?   ?   A . n 
A 1 468 SER 468 467 ?   ?   ?   A . n 
A 1 469 TYR 469 468 ?   ?   ?   A . n 
A 1 470 GLY 470 469 ?   ?   ?   A . n 
A 1 471 ASP 471 470 ?   ?   ?   A . n 
A 1 472 GLU 472 471 ?   ?   ?   A . n 
A 1 473 ILE 473 472 ?   ?   ?   A . n 
A 1 474 GLY 474 473 ?   ?   ?   A . n 
A 1 475 LEU 475 474 ?   ?   ?   A . n 
A 1 476 ASP 476 475 ?   ?   ?   A . n 
A 1 477 ALA 477 476 ?   ?   ?   A . n 
A 1 478 ALA 478 477 ?   ?   ?   A . n 
A 1 479 ALA 479 478 ?   ?   ?   A . n 
A 1 480 LEU 480 479 ?   ?   ?   A . n 
A 1 481 PRO 481 480 ?   ?   ?   A . n 
A 1 482 GLY 482 481 ?   ?   ?   A . n 
A 1 483 GLN 483 482 ?   ?   ?   A . n 
A 1 484 PRO 484 483 ?   ?   ?   A . n 
A 1 485 MET 485 484 ?   ?   ?   A . n 
A 1 486 GLU 486 485 ?   ?   ?   A . n 
A 1 487 ALA 487 486 ?   ?   ?   A . n 
A 1 488 PRO 488 487 ?   ?   ?   A . n 
A 1 489 VAL 489 488 ?   ?   ?   A . n 
A 1 490 MET 490 489 ?   ?   ?   A . n 
A 1 491 LEU 491 490 ?   ?   ?   A . n 
A 1 492 TRP 492 491 ?   ?   ?   A . n 
A 1 493 ASP 493 492 ?   ?   ?   A . n 
A 1 494 GLU 494 493 ?   ?   ?   A . n 
A 1 495 SER 495 494 ?   ?   ?   A . n 
A 1 496 SER 496 495 ?   ?   ?   A . n 
A 1 497 PHE 497 496 ?   ?   ?   A . n 
A 1 498 PRO 498 497 ?   ?   ?   A . n 
A 1 499 ASP 499 498 ?   ?   ?   A . n 
A 1 500 ILE 500 499 ?   ?   ?   A . n 
A 1 501 PRO 501 500 ?   ?   ?   A . n 
A 1 502 GLY 502 501 ?   ?   ?   A . n 
A 1 503 ALA 503 502 ?   ?   ?   A . n 
A 1 504 VAL 504 503 ?   ?   ?   A . n 
A 1 505 SER 505 504 ?   ?   ?   A . n 
A 1 506 ALA 506 505 ?   ?   ?   A . n 
A 1 507 ASN 507 506 ?   ?   ?   A . n 
A 1 508 MET 508 507 ?   ?   ?   A . n 
A 1 509 THR 509 508 ?   ?   ?   A . n 
A 1 510 VAL 510 509 ?   ?   ?   A . n 
A 1 511 LYS 511 510 ?   ?   ?   A . n 
A 1 512 GLY 512 511 ?   ?   ?   A . n 
A 1 513 GLN 513 512 ?   ?   ?   A . n 
A 1 514 SER 514 513 ?   ?   ?   A . n 
A 1 515 GLU 515 514 ?   ?   ?   A . n 
A 1 516 ASP 516 515 ?   ?   ?   A . n 
A 1 517 PRO 517 516 ?   ?   ?   A . n 
A 1 518 GLY 518 517 ?   ?   ?   A . n 
A 1 519 SER 519 518 ?   ?   ?   A . n 
A 1 520 LEU 520 519 ?   ?   ?   A . n 
A 1 521 LEU 521 520 ?   ?   ?   A . n 
A 1 522 SER 522 521 ?   ?   ?   A . n 
A 1 523 LEU 523 522 ?   ?   ?   A . n 
A 1 524 PHE 524 523 ?   ?   ?   A . n 
A 1 525 ARG 525 524 ?   ?   ?   A . n 
A 1 526 ARG 526 525 ?   ?   ?   A . n 
A 1 527 LEU 527 526 ?   ?   ?   A . n 
A 1 528 SER 528 527 ?   ?   ?   A . n 
A 1 529 ASP 529 528 ?   ?   ?   A . n 
A 1 530 GLN 530 529 ?   ?   ?   A . n 
A 1 531 ARG 531 530 ?   ?   ?   A . n 
A 1 532 SER 532 531 ?   ?   ?   A . n 
A 1 533 LYS 533 532 ?   ?   ?   A . n 
A 1 534 GLU 534 533 ?   ?   ?   A . n 
A 1 535 ARG 535 534 ?   ?   ?   A . n 
A 1 536 SER 536 535 ?   ?   ?   A . n 
A 1 537 LEU 537 536 ?   ?   ?   A . n 
A 1 538 LEU 538 537 ?   ?   ?   A . n 
A 1 539 HIS 539 538 ?   ?   ?   A . n 
A 1 540 GLY 540 539 ?   ?   ?   A . n 
A 1 541 ASP 541 540 ?   ?   ?   A . n 
A 1 542 PHE 542 541 ?   ?   ?   A . n 
A 1 543 HIS 543 542 ?   ?   ?   A . n 
A 1 544 ALA 544 543 ?   ?   ?   A . n 
A 1 545 PHE 545 544 ?   ?   ?   A . n 
A 1 546 SER 546 545 ?   ?   ?   A . n 
A 1 547 ALA 547 546 ?   ?   ?   A . n 
A 1 548 GLY 548 547 ?   ?   ?   A . n 
A 1 549 PRO 549 548 ?   ?   ?   A . n 
A 1 550 GLY 550 549 ?   ?   ?   A . n 
A 1 551 LEU 551 550 ?   ?   ?   A . n 
A 1 552 PHE 552 551 ?   ?   ?   A . n 
A 1 553 SER 553 552 ?   ?   ?   A . n 
A 1 554 TYR 554 553 ?   ?   ?   A . n 
A 1 555 ILE 555 554 ?   ?   ?   A . n 
A 1 556 ARG 556 555 ?   ?   ?   A . n 
A 1 557 HIS 557 556 ?   ?   ?   A . n 
A 1 558 TRP 558 557 ?   ?   ?   A . n 
A 1 559 ASP 559 558 ?   ?   ?   A . n 
A 1 560 GLN 560 559 ?   ?   ?   A . n 
A 1 561 ASN 561 560 ?   ?   ?   A . n 
A 1 562 GLU 562 561 ?   ?   ?   A . n 
A 1 563 ARG 563 562 ?   ?   ?   A . n 
A 1 564 PHE 564 563 ?   ?   ?   A . n 
A 1 565 LEU 565 564 ?   ?   ?   A . n 
A 1 566 VAL 566 565 ?   ?   ?   A . n 
A 1 567 VAL 567 566 ?   ?   ?   A . n 
A 1 568 LEU 568 567 ?   ?   ?   A . n 
A 1 569 ASN 569 568 ?   ?   ?   A . n 
A 1 570 PHE 570 569 ?   ?   ?   A . n 
A 1 571 GLY 571 570 ?   ?   ?   A . n 
A 1 572 ASP 572 571 ?   ?   ?   A . n 
A 1 573 VAL 573 572 ?   ?   ?   A . n 
A 1 574 GLY 574 573 ?   ?   ?   A . n 
A 1 575 LEU 575 574 ?   ?   ?   A . n 
A 1 576 SER 576 575 ?   ?   ?   A . n 
A 1 577 ALA 577 576 ?   ?   ?   A . n 
A 1 578 GLY 578 577 ?   ?   ?   A . n 
A 1 579 LEU 579 578 ?   ?   ?   A . n 
A 1 580 GLN 580 579 ?   ?   ?   A . n 
A 1 581 ALA 581 580 ?   ?   ?   A . n 
A 1 582 SER 582 581 ?   ?   ?   A . n 
A 1 583 ASP 583 582 ?   ?   ?   A . n 
A 1 584 LEU 584 583 ?   ?   ?   A . n 
A 1 585 PRO 585 584 ?   ?   ?   A . n 
A 1 586 ALA 586 585 ?   ?   ?   A . n 
A 1 587 SER 587 586 ?   ?   ?   A . n 
A 1 588 ALA 588 587 ?   ?   ?   A . n 
A 1 589 SER 589 588 ?   ?   ?   A . n 
A 1 590 LEU 590 589 ?   ?   ?   A . n 
A 1 591 PRO 591 590 ?   ?   ?   A . n 
A 1 592 ALA 592 591 ?   ?   ?   A . n 
A 1 593 LYS 593 592 ?   ?   ?   A . n 
A 1 594 ALA 594 593 ?   ?   ?   A . n 
A 1 595 ASP 595 594 ?   ?   ?   A . n 
A 1 596 LEU 596 595 ?   ?   ?   A . n 
A 1 597 LEU 597 596 ?   ?   ?   A . n 
A 1 598 LEU 598 597 ?   ?   ?   A . n 
A 1 599 SER 599 598 ?   ?   ?   A . n 
A 1 600 THR 600 599 ?   ?   ?   A . n 
A 1 601 GLN 601 600 ?   ?   ?   A . n 
A 1 602 PRO 602 601 ?   ?   ?   A . n 
A 1 603 GLY 603 602 ?   ?   ?   A . n 
A 1 604 ARG 604 603 ?   ?   ?   A . n 
A 1 605 GLU 605 604 ?   ?   ?   A . n 
A 1 606 GLU 606 605 ?   ?   ?   A . n 
A 1 607 GLY 607 606 ?   ?   ?   A . n 
A 1 608 SER 608 607 ?   ?   ?   A . n 
A 1 609 PRO 609 608 ?   ?   ?   A . n 
A 1 610 LEU 610 609 ?   ?   ?   A . n 
A 1 611 GLU 611 610 ?   ?   ?   A . n 
A 1 612 LEU 612 611 ?   ?   ?   A . n 
A 1 613 GLU 613 612 ?   ?   ?   A . n 
A 1 614 ARG 614 613 ?   ?   ?   A . n 
A 1 615 LEU 615 614 ?   ?   ?   A . n 
A 1 616 LYS 616 615 ?   ?   ?   A . n 
A 1 617 LEU 617 616 ?   ?   ?   A . n 
A 1 618 GLU 618 617 ?   ?   ?   A . n 
A 1 619 PRO 619 618 ?   ?   ?   A . n 
A 1 620 HIS 620 619 ?   ?   ?   A . n 
A 1 621 GLU 621 620 ?   ?   ?   A . n 
A 1 622 GLY 622 621 ?   ?   ?   A . n 
A 1 623 LEU 623 622 ?   ?   ?   A . n 
A 1 624 LEU 624 623 ?   ?   ?   A . n 
A 1 625 LEU 625 624 ?   ?   ?   A . n 
A 1 626 ARG 626 625 ?   ?   ?   A . n 
A 1 627 PHE 627 626 ?   ?   ?   A . n 
A 1 628 PRO 628 627 ?   ?   ?   A . n 
A 1 629 TYR 629 628 ?   ?   ?   A . n 
A 1 630 ALA 630 629 ?   ?   ?   A . n 
A 1 631 ALA 631 630 ?   ?   ?   A . n 
B 2 1   MET 1   1   ?   ?   ?   B . n 
B 2 2   ALA 2   2   ?   ?   ?   B . n 
B 2 3   GLY 3   3   ?   ?   ?   B . n 
B 2 4   ALA 4   4   ?   ?   ?   B . n 
B 2 5   GLY 5   5   ?   ?   ?   B . n 
B 2 6   PRO 6   6   ?   ?   ?   B . n 
B 2 7   LYS 7   7   ?   ?   ?   B . n 
B 2 8   ARG 8   8   ?   ?   ?   B . n 
B 2 9   ARG 9   9   ?   ?   ?   B . n 
B 2 10  ALA 10  10  ?   ?   ?   B . n 
B 2 11  LEU 11  11  ?   ?   ?   B . n 
B 2 12  ALA 12  12  ?   ?   ?   B . n 
B 2 13  ALA 13  13  ?   ?   ?   B . n 
B 2 14  PRO 14  14  ?   ?   ?   B . n 
B 2 15  ALA 15  15  ?   ?   ?   B . n 
B 2 16  ALA 16  16  ?   ?   ?   B . n 
B 2 17  GLU 17  17  ?   ?   ?   B . n 
B 2 18  GLU 18  18  ?   ?   ?   B . n 
B 2 19  LYS 19  19  ?   ?   ?   B . n 
B 2 20  GLU 20  20  ?   ?   ?   B . n 
B 2 21  GLU 21  21  ?   ?   ?   B . n 
B 2 22  ALA 22  22  ?   ?   ?   B . n 
B 2 23  ARG 23  23  ?   ?   ?   B . n 
B 2 24  GLU 24  24  ?   ?   ?   B . n 
B 2 25  LYS 25  25  ?   ?   ?   B . n 
B 2 26  MET 26  26  ?   ?   ?   B . n 
B 2 27  LEU 27  27  ?   ?   ?   B . n 
B 2 28  ALA 28  28  ?   ?   ?   B . n 
B 2 29  ALA 29  29  ?   ?   ?   B . n 
B 2 30  LYS 30  30  ?   ?   ?   B . n 
B 2 31  SER 31  31  ?   ?   ?   B . n 
B 2 32  ALA 32  32  ?   ?   ?   B . n 
B 2 33  ASP 33  33  ?   ?   ?   B . n 
B 2 34  GLY 34  34  ?   ?   ?   B . n 
B 2 35  SER 35  35  ?   ?   ?   B . n 
B 2 36  ALA 36  36  ?   ?   ?   B . n 
B 2 37  PRO 37  37  ?   ?   ?   B . n 
B 2 38  ALA 38  38  ?   ?   ?   B . n 
B 2 39  GLY 39  39  ?   ?   ?   B . n 
B 2 40  GLU 40  40  ?   ?   ?   B . n 
B 2 41  GLY 41  41  ?   ?   ?   B . n 
B 2 42  GLU 42  42  ?   ?   ?   B . n 
B 2 43  GLY 43  43  ?   ?   ?   B . n 
B 2 44  VAL 44  44  ?   ?   ?   B . n 
B 2 45  THR 45  45  ?   ?   ?   B . n 
B 2 46  LEU 46  46  ?   ?   ?   B . n 
B 2 47  GLN 47  47  ?   ?   ?   B . n 
B 2 48  ARG 48  48  ?   ?   ?   B . n 
B 2 49  ASN 49  49  ?   ?   ?   B . n 
B 2 50  ILE 50  50  ?   ?   ?   B . n 
B 2 51  THR 51  51  51  THR THR B . n 
B 2 52  LEU 52  52  52  LEU LEU B . n 
B 2 53  LEU 53  53  53  LEU LEU B . n 
B 2 54  ASN 54  54  54  ASN ASN B . n 
B 2 55  GLY 55  55  55  GLY GLY B . n 
B 2 56  VAL 56  56  56  VAL VAL B . n 
B 2 57  ALA 57  57  57  ALA ALA B . n 
B 2 58  ILE 58  58  58  ILE ILE B . n 
B 2 59  ILE 59  59  59  ILE ILE B . n 
B 2 60  VAL 60  60  60  VAL VAL B . n 
B 2 61  GLY 61  61  61  GLY GLY B . n 
B 2 62  THR 62  62  62  THR THR B . n 
B 2 63  ILE 63  63  63  ILE ILE B . n 
B 2 64  ILE 64  64  64  ILE ILE B . n 
B 2 65  GLY 65  65  65  GLY GLY B . n 
B 2 66  SER 66  66  66  SER SER B . n 
B 2 67  GLY 67  67  67  GLY GLY B . n 
B 2 68  ILE 68  68  68  ILE ILE B . n 
B 2 69  PHE 69  69  69  PHE PHE B . n 
B 2 70  VAL 70  70  70  VAL VAL B . n 
B 2 71  THR 71  71  71  THR THR B . n 
B 2 72  PRO 72  72  72  PRO PRO B . n 
B 2 73  THR 73  73  73  THR THR B . n 
B 2 74  GLY 74  74  74  GLY GLY B . n 
B 2 75  VAL 75  75  75  VAL VAL B . n 
B 2 76  LEU 76  76  76  LEU LEU B . n 
B 2 77  LYS 77  77  77  LYS LYS B . n 
B 2 78  GLU 78  78  78  GLU GLU B . n 
B 2 79  ALA 79  79  79  ALA ALA B . n 
B 2 80  GLY 80  80  80  GLY GLY B . n 
B 2 81  SER 81  81  81  SER SER B . n 
B 2 82  PRO 82  82  82  PRO PRO B . n 
B 2 83  GLY 83  83  83  GLY GLY B . n 
B 2 84  LEU 84  84  84  LEU LEU B . n 
B 2 85  ALA 85  85  85  ALA ALA B . n 
B 2 86  LEU 86  86  86  LEU LEU B . n 
B 2 87  VAL 87  87  87  VAL VAL B . n 
B 2 88  VAL 88  88  88  VAL VAL B . n 
B 2 89  TRP 89  89  89  TRP TRP B . n 
B 2 90  ALA 90  90  90  ALA ALA B . n 
B 2 91  ALA 91  91  91  ALA ALA B . n 
B 2 92  CYS 92  92  92  CYS CYS B . n 
B 2 93  GLY 93  93  93  GLY GLY B . n 
B 2 94  VAL 94  94  94  VAL VAL B . n 
B 2 95  PHE 95  95  95  PHE PHE B . n 
B 2 96  SER 96  96  96  SER SER B . n 
B 2 97  ILE 97  97  97  ILE ILE B . n 
B 2 98  VAL 98  98  98  VAL VAL B . n 
B 2 99  GLY 99  99  99  GLY GLY B . n 
B 2 100 ALA 100 100 100 ALA ALA B . n 
B 2 101 LEU 101 101 101 LEU LEU B . n 
B 2 102 CYS 102 102 102 CYS CYS B . n 
B 2 103 TYR 103 103 103 TYR TYR B . n 
B 2 104 ALA 104 104 104 ALA ALA B . n 
B 2 105 GLU 105 105 105 GLU GLU B . n 
B 2 106 LEU 106 106 106 LEU LEU B . n 
B 2 107 GLY 107 107 107 GLY GLY B . n 
B 2 108 THR 108 108 108 THR THR B . n 
B 2 109 THR 109 109 109 THR THR B . n 
B 2 110 ILE 110 110 110 ILE ILE B . n 
B 2 111 SER 111 111 111 SER SER B . n 
B 2 112 LYS 112 112 112 LYS LYS B . n 
B 2 113 SER 113 113 113 SER SER B . n 
B 2 114 GLY 114 114 114 GLY GLY B . n 
B 2 115 GLY 115 115 115 GLY GLY B . n 
B 2 116 ASP 116 116 116 ASP ASP B . n 
B 2 117 TYR 117 117 117 TYR TYR B . n 
B 2 118 ALA 118 118 118 ALA ALA B . n 
B 2 119 TYR 119 119 119 TYR TYR B . n 
B 2 120 MET 120 120 120 MET MET B . n 
B 2 121 LEU 121 121 121 LEU LEU B . n 
B 2 122 GLU 122 122 122 GLU GLU B . n 
B 2 123 VAL 123 123 123 VAL VAL B . n 
B 2 124 TYR 124 124 124 TYR TYR B . n 
B 2 125 GLY 125 125 125 GLY GLY B . n 
B 2 126 SER 126 126 126 SER SER B . n 
B 2 127 LEU 127 127 127 LEU LEU B . n 
B 2 128 PRO 128 128 128 PRO PRO B . n 
B 2 129 ALA 129 129 129 ALA ALA B . n 
B 2 130 PHE 130 130 130 PHE PHE B . n 
B 2 131 LEU 131 131 131 LEU LEU B . n 
B 2 132 LYS 132 132 132 LYS LYS B . n 
B 2 133 LEU 133 133 133 LEU LEU B . n 
B 2 134 TRP 134 134 134 TRP TRP B . n 
B 2 135 ILE 135 135 135 ILE ILE B . n 
B 2 136 GLU 136 136 136 GLU GLU B . n 
B 2 137 LEU 137 137 137 LEU LEU B . n 
B 2 138 LEU 138 138 138 LEU LEU B . n 
B 2 139 ILE 139 139 139 ILE ILE B . n 
B 2 140 ILE 140 140 140 ILE ILE B . n 
B 2 141 ARG 141 141 141 ARG ARG B . n 
B 2 142 PRO 142 142 142 PRO PRO B . n 
B 2 143 SER 143 143 143 SER SER B . n 
B 2 144 SER 144 144 144 SER SER B . n 
B 2 145 GLN 145 145 145 GLN GLN B . n 
B 2 146 TYR 146 146 146 TYR TYR B . n 
B 2 147 ILE 147 147 147 ILE ILE B . n 
B 2 148 VAL 148 148 148 VAL VAL B . n 
B 2 149 ALA 149 149 149 ALA ALA B . n 
B 2 150 LEU 150 150 150 LEU LEU B . n 
B 2 151 VAL 151 151 151 VAL VAL B . n 
B 2 152 PHE 152 152 152 PHE PHE B . n 
B 2 153 ALA 153 153 153 ALA ALA B . n 
B 2 154 THR 154 154 154 THR THR B . n 
B 2 155 TYR 155 155 155 TYR TYR B . n 
B 2 156 LEU 156 156 156 LEU LEU B . n 
B 2 157 LEU 157 157 157 LEU LEU B . n 
B 2 158 LYS 158 158 158 LYS LYS B . n 
B 2 159 PRO 159 159 159 PRO PRO B . n 
B 2 160 LEU 160 160 160 LEU LEU B . n 
B 2 161 PHE 161 161 161 PHE PHE B . n 
B 2 162 PRO 162 162 162 PRO PRO B . n 
B 2 163 THR 163 163 163 THR THR B . n 
B 2 164 CYS 164 164 164 CYS CYS B . n 
B 2 165 PRO 165 165 165 PRO PRO B . n 
B 2 166 VAL 166 166 166 VAL VAL B . n 
B 2 167 PRO 167 167 167 PRO PRO B . n 
B 2 168 GLU 168 168 168 GLU GLU B . n 
B 2 169 GLU 169 169 169 GLU GLU B . n 
B 2 170 ALA 170 170 170 ALA ALA B . n 
B 2 171 ALA 171 171 171 ALA ALA B . n 
B 2 172 LYS 172 172 172 LYS LYS B . n 
B 2 173 LEU 173 173 173 LEU LEU B . n 
B 2 174 VAL 174 174 174 VAL VAL B . n 
B 2 175 ALA 175 175 175 ALA ALA B . n 
B 2 176 CYS 176 176 176 CYS CYS B . n 
B 2 177 LEU 177 177 177 LEU LEU B . n 
B 2 178 CYS 178 178 178 CYS CYS B . n 
B 2 179 VAL 179 179 179 VAL VAL B . n 
B 2 180 LEU 180 180 180 LEU LEU B . n 
B 2 181 LEU 181 181 181 LEU LEU B . n 
B 2 182 LEU 182 182 182 LEU LEU B . n 
B 2 183 THR 183 183 183 THR THR B . n 
B 2 184 ALA 184 184 184 ALA ALA B . n 
B 2 185 VAL 185 185 185 VAL VAL B . n 
B 2 186 ASN 186 186 186 ASN ASN B . n 
B 2 187 CYS 187 187 187 CYS CYS B . n 
B 2 188 TYR 188 188 188 TYR TYR B . n 
B 2 189 SER 189 189 189 SER SER B . n 
B 2 190 VAL 190 190 190 VAL VAL B . n 
B 2 191 LYS 191 191 191 LYS LYS B . n 
B 2 192 ALA 192 192 192 ALA ALA B . n 
B 2 193 ALA 193 193 193 ALA ALA B . n 
B 2 194 THR 194 194 194 THR THR B . n 
B 2 195 ARG 195 195 195 ARG ARG B . n 
B 2 196 VAL 196 196 196 VAL VAL B . n 
B 2 197 GLN 197 197 197 GLN GLN B . n 
B 2 198 ASP 198 198 198 ASP ASP B . n 
B 2 199 ALA 199 199 199 ALA ALA B . n 
B 2 200 PHE 200 200 200 PHE PHE B . n 
B 2 201 ALA 201 201 201 ALA ALA B . n 
B 2 202 ALA 202 202 202 ALA ALA B . n 
B 2 203 ALA 203 203 203 ALA ALA B . n 
B 2 204 LYS 204 204 204 LYS LYS B . n 
B 2 205 LEU 205 205 205 LEU LEU B . n 
B 2 206 LEU 206 206 206 LEU LEU B . n 
B 2 207 ALA 207 207 207 ALA ALA B . n 
B 2 208 LEU 208 208 208 LEU LEU B . n 
B 2 209 ALA 209 209 209 ALA ALA B . n 
B 2 210 LEU 210 210 210 LEU LEU B . n 
B 2 211 ILE 211 211 211 ILE ILE B . n 
B 2 212 ILE 212 212 212 ILE ILE B . n 
B 2 213 LEU 213 213 213 LEU LEU B . n 
B 2 214 LEU 214 214 214 LEU LEU B . n 
B 2 215 GLY 215 215 215 GLY GLY B . n 
B 2 216 PHE 216 216 216 PHE PHE B . n 
B 2 217 VAL 217 217 217 VAL VAL B . n 
B 2 218 GLN 218 218 218 GLN GLN B . n 
B 2 219 ILE 219 219 219 ILE ILE B . n 
B 2 220 GLY 220 220 220 GLY GLY B . n 
B 2 221 LYS 221 221 221 LYS LYS B . n 
B 2 222 GLY 222 222 222 GLY GLY B . n 
B 2 223 ASP 223 223 ?   ?   ?   B . n 
B 2 224 VAL 224 224 ?   ?   ?   B . n 
B 2 225 SER 225 225 ?   ?   ?   B . n 
B 2 226 ASN 226 226 ?   ?   ?   B . n 
B 2 227 LEU 227 227 ?   ?   ?   B . n 
B 2 228 ASP 228 228 ?   ?   ?   B . n 
B 2 229 PRO 229 229 ?   ?   ?   B . n 
B 2 230 ASN 230 230 ?   ?   ?   B . n 
B 2 231 PHE 231 231 ?   ?   ?   B . n 
B 2 232 SER 232 232 ?   ?   ?   B . n 
B 2 233 PHE 233 233 233 PHE PHE B . n 
B 2 234 GLU 234 234 234 GLU GLU B . n 
B 2 235 GLY 235 235 235 GLY GLY B . n 
B 2 236 THR 236 236 236 THR THR B . n 
B 2 237 LYS 237 237 237 LYS LYS B . n 
B 2 238 LEU 238 238 238 LEU LEU B . n 
B 2 239 ASP 239 239 239 ASP ASP B . n 
B 2 240 VAL 240 240 240 VAL VAL B . n 
B 2 241 GLY 241 241 241 GLY GLY B . n 
B 2 242 ASN 242 242 242 ASN ASN B . n 
B 2 243 ILE 243 243 243 ILE ILE B . n 
B 2 244 VAL 244 244 244 VAL VAL B . n 
B 2 245 LEU 245 245 245 LEU LEU B . n 
B 2 246 ALA 246 246 246 ALA ALA B . n 
B 2 247 LEU 247 247 247 LEU LEU B . n 
B 2 248 TYR 248 248 248 TYR TYR B . n 
B 2 249 SER 249 249 249 SER SER B . n 
B 2 250 GLY 250 250 250 GLY GLY B . n 
B 2 251 LEU 251 251 251 LEU LEU B . n 
B 2 252 PHE 252 252 252 PHE PHE B . n 
B 2 253 ALA 253 253 253 ALA ALA B . n 
B 2 254 TYR 254 254 254 TYR TYR B . n 
B 2 255 GLY 255 255 255 GLY GLY B . n 
B 2 256 GLY 256 256 256 GLY GLY B . n 
B 2 257 TRP 257 257 257 TRP TRP B . n 
B 2 258 ASN 258 258 258 ASN ASN B . n 
B 2 259 TYR 259 259 259 TYR TYR B . n 
B 2 260 LEU 260 260 260 LEU LEU B . n 
B 2 261 ASN 261 261 261 ASN ASN B . n 
B 2 262 PHE 262 262 262 PHE PHE B . n 
B 2 263 VAL 263 263 263 VAL VAL B . n 
B 2 264 THR 264 264 264 THR THR B . n 
B 2 265 GLU 265 265 265 GLU GLU B . n 
B 2 266 GLU 266 266 266 GLU GLU B . n 
B 2 267 MET 267 267 267 MET MET B . n 
B 2 268 ILE 268 268 268 ILE ILE B . n 
B 2 269 ASN 269 269 269 ASN ASN B . n 
B 2 270 PRO 270 270 270 PRO PRO B . n 
B 2 271 TYR 271 271 271 TYR TYR B . n 
B 2 272 ARG 272 272 272 ARG ARG B . n 
B 2 273 ASN 273 273 273 ASN ASN B . n 
B 2 274 LEU 274 274 274 LEU LEU B . n 
B 2 275 PRO 275 275 275 PRO PRO B . n 
B 2 276 LEU 276 276 276 LEU LEU B . n 
B 2 277 ALA 277 277 277 ALA ALA B . n 
B 2 278 ILE 278 278 278 ILE ILE B . n 
B 2 279 ILE 279 279 279 ILE ILE B . n 
B 2 280 ILE 280 280 280 ILE ILE B . n 
B 2 281 SER 281 281 281 SER SER B . n 
B 2 282 LEU 282 282 282 LEU LEU B . n 
B 2 283 PRO 283 283 283 PRO PRO B . n 
B 2 284 ILE 284 284 284 ILE ILE B . n 
B 2 285 VAL 285 285 285 VAL VAL B . n 
B 2 286 THR 286 286 286 THR THR B . n 
B 2 287 LEU 287 287 287 LEU LEU B . n 
B 2 288 VAL 288 288 288 VAL VAL B . n 
B 2 289 TYR 289 289 289 TYR TYR B . n 
B 2 290 VAL 290 290 290 VAL VAL B . n 
B 2 291 LEU 291 291 291 LEU LEU B . n 
B 2 292 THR 292 292 292 THR THR B . n 
B 2 293 ASN 293 293 293 ASN ASN B . n 
B 2 294 LEU 294 294 294 LEU LEU B . n 
B 2 295 ALA 295 295 295 ALA ALA B . n 
B 2 296 TYR 296 296 296 TYR TYR B . n 
B 2 297 PHE 297 297 297 PHE PHE B . n 
B 2 298 THR 298 298 298 THR THR B . n 
B 2 299 THR 299 299 299 THR THR B . n 
B 2 300 LEU 300 300 300 LEU LEU B . n 
B 2 301 SER 301 301 301 SER SER B . n 
B 2 302 THR 302 302 302 THR THR B . n 
B 2 303 GLU 303 303 303 GLU GLU B . n 
B 2 304 GLN 304 304 304 GLN GLN B . n 
B 2 305 MET 305 305 305 MET MET B . n 
B 2 306 LEU 306 306 306 LEU LEU B . n 
B 2 307 SER 307 307 307 SER SER B . n 
B 2 308 SER 308 308 308 SER SER B . n 
B 2 309 GLU 309 309 309 GLU GLU B . n 
B 2 310 ALA 310 310 310 ALA ALA B . n 
B 2 311 VAL 311 311 311 VAL VAL B . n 
B 2 312 ALA 312 312 312 ALA ALA B . n 
B 2 313 VAL 313 313 313 VAL VAL B . n 
B 2 314 ASP 314 314 314 ASP ASP B . n 
B 2 315 PHE 315 315 315 PHE PHE B . n 
B 2 316 GLY 316 316 316 GLY GLY B . n 
B 2 317 ASN 317 317 317 ASN ASN B . n 
B 2 318 TYR 318 318 318 TYR TYR B . n 
B 2 319 HIS 319 319 319 HIS HIS B . n 
B 2 320 LEU 320 320 320 LEU LEU B . n 
B 2 321 GLY 321 321 321 GLY GLY B . n 
B 2 322 VAL 322 322 322 VAL VAL B . n 
B 2 323 MET 323 323 323 MET MET B . n 
B 2 324 SER 324 324 324 SER SER B . n 
B 2 325 TRP 325 325 325 TRP TRP B . n 
B 2 326 ILE 326 326 326 ILE ILE B . n 
B 2 327 ILE 327 327 327 ILE ILE B . n 
B 2 328 PRO 328 328 328 PRO PRO B . n 
B 2 329 VAL 329 329 329 VAL VAL B . n 
B 2 330 PHE 330 330 330 PHE PHE B . n 
B 2 331 VAL 331 331 331 VAL VAL B . n 
B 2 332 GLY 332 332 332 GLY GLY B . n 
B 2 333 LEU 333 333 333 LEU LEU B . n 
B 2 334 SER 334 334 334 SER SER B . n 
B 2 335 CYS 335 335 335 CYS CYS B . n 
B 2 336 PHE 336 336 336 PHE PHE B . n 
B 2 337 GLY 337 337 337 GLY GLY B . n 
B 2 338 SER 338 338 338 SER SER B . n 
B 2 339 VAL 339 339 339 VAL VAL B . n 
B 2 340 ASN 340 340 340 ASN ASN B . n 
B 2 341 GLY 341 341 341 GLY GLY B . n 
B 2 342 SER 342 342 342 SER SER B . n 
B 2 343 LEU 343 343 343 LEU LEU B . n 
B 2 344 PHE 344 344 344 PHE PHE B . n 
B 2 345 THR 345 345 345 THR THR B . n 
B 2 346 SER 346 346 346 SER SER B . n 
B 2 347 SER 347 347 347 SER SER B . n 
B 2 348 ARG 348 348 348 ARG ARG B . n 
B 2 349 LEU 349 349 349 LEU LEU B . n 
B 2 350 PHE 350 350 350 PHE PHE B . n 
B 2 351 PHE 351 351 351 PHE PHE B . n 
B 2 352 VAL 352 352 352 VAL VAL B . n 
B 2 353 GLY 353 353 353 GLY GLY B . n 
B 2 354 SER 354 354 354 SER SER B . n 
B 2 355 ARG 355 355 355 ARG ARG B . n 
B 2 356 GLU 356 356 356 GLU GLU B . n 
B 2 357 GLY 357 357 357 GLY GLY B . n 
B 2 358 HIS 358 358 358 HIS HIS B . n 
B 2 359 LEU 359 359 359 LEU LEU B . n 
B 2 360 PRO 360 360 360 PRO PRO B . n 
B 2 361 SER 361 361 361 SER SER B . n 
B 2 362 ILE 362 362 362 ILE ILE B . n 
B 2 363 LEU 363 363 363 LEU LEU B . n 
B 2 364 SER 364 364 364 SER SER B . n 
B 2 365 MET 365 365 365 MET MET B . n 
B 2 366 ILE 366 366 366 ILE ILE B . n 
B 2 367 HIS 367 367 367 HIS HIS B . n 
B 2 368 PRO 368 368 368 PRO PRO B . n 
B 2 369 GLN 369 369 369 GLN GLN B . n 
B 2 370 LEU 370 370 370 LEU LEU B . n 
B 2 371 LEU 371 371 371 LEU LEU B . n 
B 2 372 THR 372 372 372 THR THR B . n 
B 2 373 PRO 373 373 373 PRO PRO B . n 
B 2 374 VAL 374 374 374 VAL VAL B . n 
B 2 375 PRO 375 375 375 PRO PRO B . n 
B 2 376 SER 376 376 376 SER SER B . n 
B 2 377 LEU 377 377 377 LEU LEU B . n 
B 2 378 VAL 378 378 378 VAL VAL B . n 
B 2 379 PHE 379 379 379 PHE PHE B . n 
B 2 380 THR 380 380 380 THR THR B . n 
B 2 381 CYS 381 381 381 CYS CYS B . n 
B 2 382 VAL 382 382 382 VAL VAL B . n 
B 2 383 MET 383 383 383 MET MET B . n 
B 2 384 THR 384 384 384 THR THR B . n 
B 2 385 LEU 385 385 385 LEU LEU B . n 
B 2 386 LEU 386 386 386 LEU LEU B . n 
B 2 387 TYR 387 387 387 TYR TYR B . n 
B 2 388 ALA 388 388 388 ALA ALA B . n 
B 2 389 PHE 389 389 389 PHE PHE B . n 
B 2 390 SER 390 390 390 SER SER B . n 
B 2 391 LYS 391 391 391 LYS LYS B . n 
B 2 392 ASP 392 392 392 ASP ASP B . n 
B 2 393 ILE 393 393 393 ILE ILE B . n 
B 2 394 PHE 394 394 394 PHE PHE B . n 
B 2 395 SER 395 395 395 SER SER B . n 
B 2 396 VAL 396 396 396 VAL VAL B . n 
B 2 397 ILE 397 397 397 ILE ILE B . n 
B 2 398 ASN 398 398 398 ASN ASN B . n 
B 2 399 PHE 399 399 399 PHE PHE B . n 
B 2 400 PHE 400 400 400 PHE PHE B . n 
B 2 401 SER 401 401 401 SER SER B . n 
B 2 402 PHE 402 402 402 PHE PHE B . n 
B 2 403 PHE 403 403 403 PHE PHE B . n 
B 2 404 ASN 404 404 404 ASN ASN B . n 
B 2 405 TRP 405 405 405 TRP TRP B . n 
B 2 406 LEU 406 406 406 LEU LEU B . n 
B 2 407 CYS 407 407 407 CYS CYS B . n 
B 2 408 VAL 408 408 408 VAL VAL B . n 
B 2 409 ALA 409 409 409 ALA ALA B . n 
B 2 410 LEU 410 410 410 LEU LEU B . n 
B 2 411 ALA 411 411 411 ALA ALA B . n 
B 2 412 ILE 412 412 412 ILE ILE B . n 
B 2 413 ILE 413 413 413 ILE ILE B . n 
B 2 414 GLY 414 414 414 GLY GLY B . n 
B 2 415 MET 415 415 415 MET MET B . n 
B 2 416 ILE 416 416 416 ILE ILE B . n 
B 2 417 TRP 417 417 417 TRP TRP B . n 
B 2 418 LEU 418 418 418 LEU LEU B . n 
B 2 419 ARG 419 419 419 ARG ARG B . n 
B 2 420 HIS 420 420 420 HIS HIS B . n 
B 2 421 ARG 421 421 421 ARG ARG B . n 
B 2 422 LYS 422 422 422 LYS LYS B . n 
B 2 423 PRO 423 423 423 PRO PRO B . n 
B 2 424 GLU 424 424 424 GLU GLU B . n 
B 2 425 LEU 425 425 425 LEU LEU B . n 
B 2 426 GLU 426 426 426 GLU GLU B . n 
B 2 427 ARG 427 427 427 ARG ARG B . n 
B 2 428 PRO 428 428 428 PRO PRO B . n 
B 2 429 ILE 429 429 429 ILE ILE B . n 
B 2 430 LYS 430 430 430 LYS LYS B . n 
B 2 431 VAL 431 431 431 VAL VAL B . n 
B 2 432 ASN 432 432 432 ASN ASN B . n 
B 2 433 LEU 433 433 433 LEU LEU B . n 
B 2 434 ALA 434 434 434 ALA ALA B . n 
B 2 435 LEU 435 435 435 LEU LEU B . n 
B 2 436 PRO 436 436 436 PRO PRO B . n 
B 2 437 VAL 437 437 437 VAL VAL B . n 
B 2 438 PHE 438 438 438 PHE PHE B . n 
B 2 439 PHE 439 439 439 PHE PHE B . n 
B 2 440 ILE 440 440 440 ILE ILE B . n 
B 2 441 LEU 441 441 441 LEU LEU B . n 
B 2 442 ALA 442 442 442 ALA ALA B . n 
B 2 443 CYS 443 443 443 CYS CYS B . n 
B 2 444 LEU 444 444 444 LEU LEU B . n 
B 2 445 PHE 445 445 445 PHE PHE B . n 
B 2 446 LEU 446 446 446 LEU LEU B . n 
B 2 447 ILE 447 447 447 ILE ILE B . n 
B 2 448 ALA 448 448 448 ALA ALA B . n 
B 2 449 VAL 449 449 449 VAL VAL B . n 
B 2 450 SER 450 450 450 SER SER B . n 
B 2 451 PHE 451 451 451 PHE PHE B . n 
B 2 452 TRP 452 452 452 TRP TRP B . n 
B 2 453 LYS 453 453 453 LYS LYS B . n 
B 2 454 THR 454 454 454 THR THR B . n 
B 2 455 PRO 455 455 455 PRO PRO B . n 
B 2 456 VAL 456 456 456 VAL VAL B . n 
B 2 457 GLU 457 457 457 GLU GLU B . n 
B 2 458 CYS 458 458 458 CYS CYS B . n 
B 2 459 GLY 459 459 459 GLY GLY B . n 
B 2 460 ILE 460 460 460 ILE ILE B . n 
B 2 461 GLY 461 461 461 GLY GLY B . n 
B 2 462 PHE 462 462 462 PHE PHE B . n 
B 2 463 THR 463 463 463 THR THR B . n 
B 2 464 ILE 464 464 464 ILE ILE B . n 
B 2 465 ILE 465 465 465 ILE ILE B . n 
B 2 466 LEU 466 466 466 LEU LEU B . n 
B 2 467 SER 467 467 467 SER SER B . n 
B 2 468 GLY 468 468 468 GLY GLY B . n 
B 2 469 LEU 469 469 469 LEU LEU B . n 
B 2 470 PRO 470 470 470 PRO PRO B . n 
B 2 471 VAL 471 471 471 VAL VAL B . n 
B 2 472 TYR 472 472 472 TYR TYR B . n 
B 2 473 PHE 473 473 473 PHE PHE B . n 
B 2 474 PHE 474 474 474 PHE PHE B . n 
B 2 475 GLY 475 475 475 GLY GLY B . n 
B 2 476 VAL 476 476 476 VAL VAL B . n 
B 2 477 TRP 477 477 477 TRP TRP B . n 
B 2 478 TRP 478 478 478 TRP TRP B . n 
B 2 479 LYS 479 479 479 LYS LYS B . n 
B 2 480 ASN 480 480 480 ASN ASN B . n 
B 2 481 LYS 481 481 481 LYS LYS B . n 
B 2 482 PRO 482 482 482 PRO PRO B . n 
B 2 483 LYS 483 483 483 LYS LYS B . n 
B 2 484 TRP 484 484 484 TRP TRP B . n 
B 2 485 LEU 485 485 485 LEU LEU B . n 
B 2 486 LEU 486 486 486 LEU LEU B . n 
B 2 487 GLN 487 487 487 GLN GLN B . n 
B 2 488 GLY 488 488 488 GLY GLY B . n 
B 2 489 ILE 489 489 489 ILE ILE B . n 
B 2 490 PHE 490 490 490 PHE PHE B . n 
B 2 491 SER 491 491 491 SER SER B . n 
B 2 492 THR 492 492 492 THR THR B . n 
B 2 493 THR 493 493 493 THR THR B . n 
B 2 494 VAL 494 494 494 VAL VAL B . n 
B 2 495 LEU 495 495 495 LEU LEU B . n 
B 2 496 CYS 496 496 496 CYS CYS B . n 
B 2 497 GLN 497 497 497 GLN GLN B . n 
B 2 498 LYS 498 498 498 LYS LYS B . n 
B 2 499 LEU 499 499 499 LEU LEU B . n 
B 2 500 MET 500 500 500 MET MET B . n 
B 2 501 GLN 501 501 501 GLN GLN B . n 
B 2 502 VAL 502 502 502 VAL VAL B . n 
B 2 503 VAL 503 503 503 VAL VAL B . n 
B 2 504 PRO 504 504 504 PRO PRO B . n 
B 2 505 GLN 505 505 505 GLN GLN B . n 
B 2 506 GLU 506 506 506 GLU GLU B . n 
B 2 507 THR 507 507 507 THR THR B . n 
B 2 508 ASP 508 508 ?   ?   ?   B . n 
B 2 509 TYR 509 509 ?   ?   ?   B . n 
B 2 510 LYS 510 510 ?   ?   ?   B . n 
B 2 511 ASP 511 511 ?   ?   ?   B . n 
B 2 512 ASP 512 512 ?   ?   ?   B . n 
B 2 513 ASP 513 513 ?   ?   ?   B . n 
B 2 514 ASP 514 514 ?   ?   ?   B . n 
B 2 515 LYS 515 515 ?   ?   ?   B . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 3 CLR 1 701 601 CLR CRL A . 
D 4 LBN 1 702 603 LBN POV A . 
E 3 CLR 1 601 602 CLR CRL B . 
F 3 CLR 1 602 604 CLR CRL B . 
G 4 LBN 1 603 605 LBN POV B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 N 1 A LBN 702 ? C5  ? D LBN 1 C5  
2  1 N 1 A LBN 702 ? C7  ? D LBN 1 C7  
3  1 N 1 A LBN 702 ? C8  ? D LBN 1 C8  
4  1 N 1 A LBN 702 ? C10 ? D LBN 1 C10 
5  1 N 1 A LBN 702 ? C11 ? D LBN 1 C11 
6  1 N 1 A LBN 702 ? C13 ? D LBN 1 C13 
7  1 N 1 A LBN 702 ? C14 ? D LBN 1 C14 
8  1 N 1 A LBN 702 ? C16 ? D LBN 1 C16 
9  1 N 1 A LBN 702 ? C17 ? D LBN 1 C17 
10 1 N 1 A LBN 702 ? C19 ? D LBN 1 C19 
11 1 N 1 A LBN 702 ? C20 ? D LBN 1 C20 
12 1 N 1 A LBN 702 ? C21 ? D LBN 1 C21 
13 1 N 1 A LBN 702 ? C22 ? D LBN 1 C22 
14 1 N 1 A LBN 702 ? C23 ? D LBN 1 C23 
15 1 N 1 A LBN 702 ? C24 ? D LBN 1 C24 
16 1 N 1 B LBN 603 ? C4  ? G LBN 1 C4  
17 1 N 1 B LBN 603 ? C5  ? G LBN 1 C5  
18 1 N 1 B LBN 603 ? C7  ? G LBN 1 C7  
19 1 N 1 B LBN 603 ? C8  ? G LBN 1 C8  
20 1 N 1 B LBN 603 ? C10 ? G LBN 1 C10 
21 1 N 1 B LBN 603 ? C11 ? G LBN 1 C11 
22 1 N 1 B LBN 603 ? C13 ? G LBN 1 C13 
23 1 N 1 B LBN 603 ? C14 ? G LBN 1 C14 
24 1 N 1 B LBN 603 ? C16 ? G LBN 1 C16 
25 1 N 1 B LBN 603 ? C17 ? G LBN 1 C17 
26 1 N 1 B LBN 603 ? C19 ? G LBN 1 C19 
27 1 N 1 B LBN 603 ? C20 ? G LBN 1 C20 
28 1 N 1 B LBN 603 ? C21 ? G LBN 1 C21 
29 1 N 1 B LBN 603 ? C22 ? G LBN 1 C22 
30 1 N 1 B LBN 603 ? C23 ? G LBN 1 C23 
31 1 N 1 B LBN 603 ? C24 ? G LBN 1 C24 
32 1 N 1 B LBN 603 ? C30 ? G LBN 1 C30 
33 1 N 1 B LBN 603 ? C31 ? G LBN 1 C31 
34 1 N 1 B LBN 603 ? C32 ? G LBN 1 C32 
35 1 N 1 B LBN 603 ? C33 ? G LBN 1 C33 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8KDJ 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8KDJ 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8KDJ 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               218.719 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.927 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  'HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8KDJ 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.73 
_refine.ls_d_res_low                             3.73 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     27210 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    100.00 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.34591 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.34591 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'PARAMETERS FOR MASK CACLULATION' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD WITH PHASES' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.768 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             17.810 
_refine.overall_SU_ML                            0.255 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'ELECTRON MICROSCOPY' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       . 
_refine_hist.d_res_low                        . 
_refine_hist.number_atoms_solvent             ? 
_refine_hist.number_atoms_total               4013 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        ? 
_refine_hist.pdbx_number_atoms_nucleic_acid   ? 
_refine_hist.pdbx_number_atoms_ligand         ? 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.010  0.012  4124  ? r_bond_refined_d             ? ? 
'ELECTRON MICROSCOPY' ? 0.000  0.016  4172  ? r_bond_other_d               ? ? 
'ELECTRON MICROSCOPY' ? 1.924  1.626  5640  ? r_angle_refined_deg          ? ? 
'ELECTRON MICROSCOPY' ? 0.635  1.551  9588  ? r_angle_other_deg            ? ? 
'ELECTRON MICROSCOPY' ? 7.308  5.000  496   ? r_dihedral_angle_1_deg       ? ? 
'ELECTRON MICROSCOPY' ? 21.720 6.750  20    ? r_dihedral_angle_2_deg       ? ? 
'ELECTRON MICROSCOPY' ? 14.132 10.000 639   ? r_dihedral_angle_3_deg       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_dihedral_angle_4_deg       ? ? 
'ELECTRON MICROSCOPY' ? 0.088  0.200  684   ? r_chiral_restr               ? ? 
'ELECTRON MICROSCOPY' ? 0.004  0.020  4518  ? r_gen_planes_refined         ? ? 
'ELECTRON MICROSCOPY' ? 0.001  0.020  906   ? r_gen_planes_other           ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'ELECTRON MICROSCOPY' ? 35.733 18.672 1993  ? r_mcbond_it                  ? ? 
'ELECTRON MICROSCOPY' ? 35.733 18.674 1993  ? r_mcbond_other               ? ? 
'ELECTRON MICROSCOPY' ? 49.903 33.856 2486  ? r_mcangle_it                 ? ? 
'ELECTRON MICROSCOPY' ? 49.898 33.872 2487  ? r_mcangle_other              ? ? 
'ELECTRON MICROSCOPY' ? 40.487 23.569 2131  ? r_scbond_it                  ? ? 
'ELECTRON MICROSCOPY' ? 40.478 23.569 2132  ? r_scbond_other               ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'ELECTRON MICROSCOPY' ? 61.459 41.570 3155  ? r_scangle_other              ? ? 
'ELECTRON MICROSCOPY' ? 69.690 233.97 16240 ? r_long_range_B_refined       ? ? 
'ELECTRON MICROSCOPY' ? 69.688 233.97 16241 ? r_long_range_B_other         ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'ELECTRON MICROSCOPY' 
_refine_ls_shell.d_res_high                       3.701 
_refine_ls_shell.d_res_low                        3.796 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             0 
_refine_ls_shell.number_reflns_R_work             2039 
_refine_ls_shell.percent_reflns_obs               100.00 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  2.011 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.000 
# 
_struct.entry_id                     8KDJ 
_struct.title                        'Structure of apo inward-open LAT1-CD98h in nanodisc, focused on TMD' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8KDJ 
_struct_keywords.text            'Transporter, Amino acid, Complex, Cancer, TRANSPORT PROTEIN' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 3 ? 
F N N 3 ? 
G N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP 4F2_HUMAN  P08195 ? 1 
;ELQPPEASIAVVSIPRQLPGSHSEAGVQGLSAGDDSELGSHCVAQTGLELLASGDPLPSASQNAEMIETGSDCVTQAGLQ
LLASSDPPALASKNAEVTGTMSQDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEKNGLVKIKVAEDEAEAAAAAKF
TGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAGNL
AGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWFST
QVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQILSLLESNKDLLLT
SSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAALPG
QPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQNE
RFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPYAA
;
2 
2 UNP LAT1_HUMAN Q01650 ? 2 
;MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAG
SPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPL
FPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV
GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHL
GVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFF
SFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN
KPKWLLQGIFSTTVLCQKLMQVVPQET
;
1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8KDJ A 3 ? 631 ? P08195 2 ? 630 ? 2 630 
2 2 8KDJ B 1 ? 507 ? Q01650 1 ? 507 ? 1 507 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8KDJ GLY A 1   ? UNP P08195 ? ? 'expression tag' 0   1  
1 8KDJ SER A 2   ? UNP P08195 ? ? 'expression tag' 1   2  
2 8KDJ ASP B 508 ? UNP Q01650 ? ? 'expression tag' 508 3  
2 8KDJ TYR B 509 ? UNP Q01650 ? ? 'expression tag' 509 4  
2 8KDJ LYS B 510 ? UNP Q01650 ? ? 'expression tag' 510 5  
2 8KDJ ASP B 511 ? UNP Q01650 ? ? 'expression tag' 511 6  
2 8KDJ ASP B 512 ? UNP Q01650 ? ? 'expression tag' 512 7  
2 8KDJ ASP B 513 ? UNP Q01650 ? ? 'expression tag' 513 8  
2 8KDJ ASP B 514 ? UNP Q01650 ? ? 'expression tag' 514 9  
2 8KDJ LYS B 515 ? UNP Q01650 ? ? 'expression tag' 515 10 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 166 ? ALA A 174 ? SER A 165 ALA A 173 1 ? 9  
HELX_P HELX_P2  AA2 GLY A 178 ? ALA A 208 ? GLY A 177 ALA A 207 1 ? 31 
HELX_P HELX_P3  AA3 LEU B 52  ? ILE B 64  ? LEU B 52  ILE B 64  1 ? 13 
HELX_P HELX_P4  AA4 SER B 66  ? VAL B 70  ? SER B 66  VAL B 70  5 ? 5  
HELX_P HELX_P5  AA5 THR B 71  ? GLY B 80  ? THR B 71  GLY B 80  1 ? 10 
HELX_P HELX_P6  AA6 SER B 81  ? ILE B 110 ? SER B 81  ILE B 110 1 ? 30 
HELX_P HELX_P7  AA7 GLY B 115 ? TYR B 124 ? GLY B 115 TYR B 124 1 ? 10 
HELX_P HELX_P8  AA8 GLY B 125 ? ILE B 139 ? GLY B 125 ILE B 139 1 ? 15 
HELX_P HELX_P9  AA9 ILE B 139 ? LYS B 158 ? ILE B 139 LYS B 158 1 ? 20 
HELX_P HELX_P10 AB1 PRO B 159 ? PHE B 161 ? PRO B 159 PHE B 161 5 ? 3  
HELX_P HELX_P11 AB2 PRO B 167 ? SER B 189 ? PRO B 167 SER B 189 1 ? 23 
HELX_P HELX_P12 AB3 SER B 189 ? GLY B 222 ? SER B 189 GLY B 222 1 ? 34 
HELX_P HELX_P13 AB4 ASP B 239 ? TYR B 254 ? ASP B 239 TYR B 254 1 ? 16 
HELX_P HELX_P14 AB5 GLY B 256 ? ASN B 261 ? GLY B 256 ASN B 261 1 ? 6  
HELX_P HELX_P15 AB6 PHE B 262 ? MET B 267 ? PHE B 262 MET B 267 5 ? 6  
HELX_P HELX_P16 AB7 ARG B 272 ? THR B 298 ? ARG B 272 THR B 298 1 ? 27 
HELX_P HELX_P17 AB8 SER B 301 ? LEU B 306 ? SER B 301 LEU B 306 1 ? 6  
HELX_P HELX_P18 AB9 ALA B 310 ? LEU B 320 ? ALA B 310 LEU B 320 1 ? 11 
HELX_P HELX_P19 AC1 VAL B 322 ? TRP B 325 ? VAL B 322 TRP B 325 5 ? 4  
HELX_P HELX_P20 AC2 ILE B 326 ? THR B 345 ? ILE B 326 THR B 345 1 ? 20 
HELX_P HELX_P21 AC3 SER B 346 ? GLU B 356 ? SER B 346 GLU B 356 1 ? 11 
HELX_P HELX_P22 AC4 PRO B 360 ? MET B 365 ? PRO B 360 MET B 365 5 ? 6  
HELX_P HELX_P23 AC5 PRO B 373 ? TYR B 387 ? PRO B 373 TYR B 387 1 ? 15 
HELX_P HELX_P24 AC6 ALA B 388 ? SER B 390 ? ALA B 388 SER B 390 5 ? 3  
HELX_P HELX_P25 AC7 ASP B 392 ? LYS B 422 ? ASP B 392 LYS B 422 1 ? 31 
HELX_P HELX_P26 AC8 LEU B 435 ? THR B 454 ? LEU B 435 THR B 454 1 ? 20 
HELX_P HELX_P27 AC9 THR B 454 ? SER B 467 ? THR B 454 SER B 467 1 ? 14 
HELX_P HELX_P28 AD1 SER B 467 ? VAL B 476 ? SER B 467 VAL B 476 1 ? 10 
HELX_P HELX_P29 AD2 PRO B 482 ? GLN B 501 ? PRO B 482 GLN B 501 1 ? 20 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            disulf1 
_struct_conn.conn_type_id                  disulf 
_struct_conn.pdbx_leaving_atom_flag        ? 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           A 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            211 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           B 
_struct_conn.ptnr2_label_comp_id           CYS 
_struct_conn.ptnr2_label_seq_id            164 
_struct_conn.ptnr2_label_atom_id           SG 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            A 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             210 
_struct_conn.ptnr2_auth_asym_id            B 
_struct_conn.ptnr2_auth_comp_id            CYS 
_struct_conn.ptnr2_auth_seq_id             164 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               2.095 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      CYS 
_pdbx_modification_feature.label_asym_id                      A 
_pdbx_modification_feature.label_seq_id                       211 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     B 
_pdbx_modification_feature.modified_residue_label_seq_id      164 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       CYS 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        210 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      B 
_pdbx_modification_feature.modified_residue_auth_seq_id       164 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               SG 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                . 
_pdbx_modification_feature.ref_pcm_id                         . 
_pdbx_modification_feature.ref_comp_id                        . 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Disulfide bridge' 
# 
_pdbx_entry_details.entry_id                   8KDJ 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   O 
_pdbx_validate_close_contact.auth_asym_id_1   B 
_pdbx_validate_close_contact.auth_comp_id_1   GLY 
_pdbx_validate_close_contact.auth_seq_id_1    475 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   O8 
_pdbx_validate_close_contact.auth_asym_id_2   B 
_pdbx_validate_close_contact.auth_comp_id_2   LBN 
_pdbx_validate_close_contact.auth_seq_id_2    603 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             1.99 
# 
_pdbx_validate_rmsd_bond.id                        1 
_pdbx_validate_rmsd_bond.PDB_model_num             1 
_pdbx_validate_rmsd_bond.auth_atom_id_1            CD 
_pdbx_validate_rmsd_bond.auth_asym_id_1            B 
_pdbx_validate_rmsd_bond.auth_comp_id_1            GLU 
_pdbx_validate_rmsd_bond.auth_seq_id_1             303 
_pdbx_validate_rmsd_bond.PDB_ins_code_1            ? 
_pdbx_validate_rmsd_bond.label_alt_id_1            ? 
_pdbx_validate_rmsd_bond.auth_atom_id_2            OE1 
_pdbx_validate_rmsd_bond.auth_asym_id_2            B 
_pdbx_validate_rmsd_bond.auth_comp_id_2            GLU 
_pdbx_validate_rmsd_bond.auth_seq_id_2             303 
_pdbx_validate_rmsd_bond.PDB_ins_code_2            ? 
_pdbx_validate_rmsd_bond.label_alt_id_2            ? 
_pdbx_validate_rmsd_bond.bond_value                1.318 
_pdbx_validate_rmsd_bond.bond_target_value         1.252 
_pdbx_validate_rmsd_bond.bond_deviation            0.066 
_pdbx_validate_rmsd_bond.bond_standard_deviation   0.011 
_pdbx_validate_rmsd_bond.linker_flag               N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CB B TYR 289 ? ? CG B TYR 289 ? ? CD2 B TYR 289 ? ? 116.01 121.00 -4.99 0.60 N 
2 1 CB B TYR 289 ? ? CG B TYR 289 ? ? CD1 B TYR 289 ? ? 124.90 121.00 3.90  0.60 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 SER B 111 ? ? 58.72   -0.37   
2 1 TYR B 124 ? ? -134.51 -38.60  
3 1 SER B 126 ? ? 50.67   -125.43 
4 1 SER B 189 ? ? -166.13 111.62  
5 1 LEU B 238 ? ? -142.90 20.85   
6 1 LEU B 260 ? ? -143.00 -3.15   
7 1 ILE B 326 ? ? -116.85 -87.43  
8 1 VAL B 476 ? ? -134.95 -52.92  
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG B 141 ? ? 0.099 'SIDE CHAIN' 
2 1 ARG B 427 ? ? 0.089 'SIDE CHAIN' 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8KDJ 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8KDJ 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.73 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               242503 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 LAT1-CD98hc-Fab170 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_imaging.entry_id                        8KDJ 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8KDJ 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8KDJ 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A GLY 0   ? A GLY 1   
2   1 Y 1 A SER 1   ? A SER 2   
3   1 Y 1 A GLU 2   ? A GLU 3   
4   1 Y 1 A LEU 3   ? A LEU 4   
5   1 Y 1 A GLN 4   ? A GLN 5   
6   1 Y 1 A PRO 5   ? A PRO 6   
7   1 Y 1 A PRO 6   ? A PRO 7   
8   1 Y 1 A GLU 7   ? A GLU 8   
9   1 Y 1 A ALA 8   ? A ALA 9   
10  1 Y 1 A SER 9   ? A SER 10  
11  1 Y 1 A ILE 10  ? A ILE 11  
12  1 Y 1 A ALA 11  ? A ALA 12  
13  1 Y 1 A VAL 12  ? A VAL 13  
14  1 Y 1 A VAL 13  ? A VAL 14  
15  1 Y 1 A SER 14  ? A SER 15  
16  1 Y 1 A ILE 15  ? A ILE 16  
17  1 Y 1 A PRO 16  ? A PRO 17  
18  1 Y 1 A ARG 17  ? A ARG 18  
19  1 Y 1 A GLN 18  ? A GLN 19  
20  1 Y 1 A LEU 19  ? A LEU 20  
21  1 Y 1 A PRO 20  ? A PRO 21  
22  1 Y 1 A GLY 21  ? A GLY 22  
23  1 Y 1 A SER 22  ? A SER 23  
24  1 Y 1 A HIS 23  ? A HIS 24  
25  1 Y 1 A SER 24  ? A SER 25  
26  1 Y 1 A GLU 25  ? A GLU 26  
27  1 Y 1 A ALA 26  ? A ALA 27  
28  1 Y 1 A GLY 27  ? A GLY 28  
29  1 Y 1 A VAL 28  ? A VAL 29  
30  1 Y 1 A GLN 29  ? A GLN 30  
31  1 Y 1 A GLY 30  ? A GLY 31  
32  1 Y 1 A LEU 31  ? A LEU 32  
33  1 Y 1 A SER 32  ? A SER 33  
34  1 Y 1 A ALA 33  ? A ALA 34  
35  1 Y 1 A GLY 34  ? A GLY 35  
36  1 Y 1 A ASP 35  ? A ASP 36  
37  1 Y 1 A ASP 36  ? A ASP 37  
38  1 Y 1 A SER 37  ? A SER 38  
39  1 Y 1 A GLU 38  ? A GLU 39  
40  1 Y 1 A LEU 39  ? A LEU 40  
41  1 Y 1 A GLY 40  ? A GLY 41  
42  1 Y 1 A SER 41  ? A SER 42  
43  1 Y 1 A HIS 42  ? A HIS 43  
44  1 Y 1 A CYS 43  ? A CYS 44  
45  1 Y 1 A VAL 44  ? A VAL 45  
46  1 Y 1 A ALA 45  ? A ALA 46  
47  1 Y 1 A GLN 46  ? A GLN 47  
48  1 Y 1 A THR 47  ? A THR 48  
49  1 Y 1 A GLY 48  ? A GLY 49  
50  1 Y 1 A LEU 49  ? A LEU 50  
51  1 Y 1 A GLU 50  ? A GLU 51  
52  1 Y 1 A LEU 51  ? A LEU 52  
53  1 Y 1 A LEU 52  ? A LEU 53  
54  1 Y 1 A ALA 53  ? A ALA 54  
55  1 Y 1 A SER 54  ? A SER 55  
56  1 Y 1 A GLY 55  ? A GLY 56  
57  1 Y 1 A ASP 56  ? A ASP 57  
58  1 Y 1 A PRO 57  ? A PRO 58  
59  1 Y 1 A LEU 58  ? A LEU 59  
60  1 Y 1 A PRO 59  ? A PRO 60  
61  1 Y 1 A SER 60  ? A SER 61  
62  1 Y 1 A ALA 61  ? A ALA 62  
63  1 Y 1 A SER 62  ? A SER 63  
64  1 Y 1 A GLN 63  ? A GLN 64  
65  1 Y 1 A ASN 64  ? A ASN 65  
66  1 Y 1 A ALA 65  ? A ALA 66  
67  1 Y 1 A GLU 66  ? A GLU 67  
68  1 Y 1 A MET 67  ? A MET 68  
69  1 Y 1 A ILE 68  ? A ILE 69  
70  1 Y 1 A GLU 69  ? A GLU 70  
71  1 Y 1 A THR 70  ? A THR 71  
72  1 Y 1 A GLY 71  ? A GLY 72  
73  1 Y 1 A SER 72  ? A SER 73  
74  1 Y 1 A ASP 73  ? A ASP 74  
75  1 Y 1 A CYS 74  ? A CYS 75  
76  1 Y 1 A VAL 75  ? A VAL 76  
77  1 Y 1 A THR 76  ? A THR 77  
78  1 Y 1 A GLN 77  ? A GLN 78  
79  1 Y 1 A ALA 78  ? A ALA 79  
80  1 Y 1 A GLY 79  ? A GLY 80  
81  1 Y 1 A LEU 80  ? A LEU 81  
82  1 Y 1 A GLN 81  ? A GLN 82  
83  1 Y 1 A LEU 82  ? A LEU 83  
84  1 Y 1 A LEU 83  ? A LEU 84  
85  1 Y 1 A ALA 84  ? A ALA 85  
86  1 Y 1 A SER 85  ? A SER 86  
87  1 Y 1 A SER 86  ? A SER 87  
88  1 Y 1 A ASP 87  ? A ASP 88  
89  1 Y 1 A PRO 88  ? A PRO 89  
90  1 Y 1 A PRO 89  ? A PRO 90  
91  1 Y 1 A ALA 90  ? A ALA 91  
92  1 Y 1 A LEU 91  ? A LEU 92  
93  1 Y 1 A ALA 92  ? A ALA 93  
94  1 Y 1 A SER 93  ? A SER 94  
95  1 Y 1 A LYS 94  ? A LYS 95  
96  1 Y 1 A ASN 95  ? A ASN 96  
97  1 Y 1 A ALA 96  ? A ALA 97  
98  1 Y 1 A GLU 97  ? A GLU 98  
99  1 Y 1 A VAL 98  ? A VAL 99  
100 1 Y 1 A THR 99  ? A THR 100 
101 1 Y 1 A GLY 100 ? A GLY 101 
102 1 Y 1 A THR 101 ? A THR 102 
103 1 Y 1 A MET 102 ? A MET 103 
104 1 Y 1 A SER 103 ? A SER 104 
105 1 Y 1 A GLN 104 ? A GLN 105 
106 1 Y 1 A ASP 105 ? A ASP 106 
107 1 Y 1 A THR 106 ? A THR 107 
108 1 Y 1 A GLU 107 ? A GLU 108 
109 1 Y 1 A VAL 108 ? A VAL 109 
110 1 Y 1 A ASP 109 ? A ASP 110 
111 1 Y 1 A MET 110 ? A MET 111 
112 1 Y 1 A LYS 111 ? A LYS 112 
113 1 Y 1 A GLU 112 ? A GLU 113 
114 1 Y 1 A VAL 113 ? A VAL 114 
115 1 Y 1 A GLU 114 ? A GLU 115 
116 1 Y 1 A LEU 115 ? A LEU 116 
117 1 Y 1 A ASN 116 ? A ASN 117 
118 1 Y 1 A GLU 117 ? A GLU 118 
119 1 Y 1 A LEU 118 ? A LEU 119 
120 1 Y 1 A GLU 119 ? A GLU 120 
121 1 Y 1 A PRO 120 ? A PRO 121 
122 1 Y 1 A GLU 121 ? A GLU 122 
123 1 Y 1 A LYS 122 ? A LYS 123 
124 1 Y 1 A GLN 123 ? A GLN 124 
125 1 Y 1 A PRO 124 ? A PRO 125 
126 1 Y 1 A MET 125 ? A MET 126 
127 1 Y 1 A ASN 126 ? A ASN 127 
128 1 Y 1 A ALA 127 ? A ALA 128 
129 1 Y 1 A ALA 128 ? A ALA 129 
130 1 Y 1 A SER 129 ? A SER 130 
131 1 Y 1 A GLY 130 ? A GLY 131 
132 1 Y 1 A ALA 131 ? A ALA 132 
133 1 Y 1 A ALA 132 ? A ALA 133 
134 1 Y 1 A MET 133 ? A MET 134 
135 1 Y 1 A SER 134 ? A SER 135 
136 1 Y 1 A LEU 135 ? A LEU 136 
137 1 Y 1 A ALA 136 ? A ALA 137 
138 1 Y 1 A GLY 137 ? A GLY 138 
139 1 Y 1 A ALA 138 ? A ALA 139 
140 1 Y 1 A GLU 139 ? A GLU 140 
141 1 Y 1 A LYS 140 ? A LYS 141 
142 1 Y 1 A ASN 141 ? A ASN 142 
143 1 Y 1 A GLY 142 ? A GLY 143 
144 1 Y 1 A LEU 143 ? A LEU 144 
145 1 Y 1 A VAL 144 ? A VAL 145 
146 1 Y 1 A LYS 145 ? A LYS 146 
147 1 Y 1 A ILE 146 ? A ILE 147 
148 1 Y 1 A LYS 147 ? A LYS 148 
149 1 Y 1 A VAL 148 ? A VAL 149 
150 1 Y 1 A ALA 149 ? A ALA 150 
151 1 Y 1 A GLU 150 ? A GLU 151 
152 1 Y 1 A ASP 151 ? A ASP 152 
153 1 Y 1 A GLU 152 ? A GLU 153 
154 1 Y 1 A ALA 153 ? A ALA 154 
155 1 Y 1 A GLU 154 ? A GLU 155 
156 1 Y 1 A ALA 155 ? A ALA 156 
157 1 Y 1 A ALA 156 ? A ALA 157 
158 1 Y 1 A ALA 157 ? A ALA 158 
159 1 Y 1 A ALA 158 ? A ALA 159 
160 1 Y 1 A ALA 159 ? A ALA 160 
161 1 Y 1 A LYS 160 ? A LYS 161 
162 1 Y 1 A PHE 161 ? A PHE 162 
163 1 Y 1 A PRO 214 ? A PRO 215 
164 1 Y 1 A ALA 215 ? A ALA 216 
165 1 Y 1 A GLN 216 ? A GLN 217 
166 1 Y 1 A LYS 217 ? A LYS 218 
167 1 Y 1 A TRP 218 ? A TRP 219 
168 1 Y 1 A TRP 219 ? A TRP 220 
169 1 Y 1 A HIS 220 ? A HIS 221 
170 1 Y 1 A THR 221 ? A THR 222 
171 1 Y 1 A GLY 222 ? A GLY 223 
172 1 Y 1 A ALA 223 ? A ALA 224 
173 1 Y 1 A LEU 224 ? A LEU 225 
174 1 Y 1 A TYR 225 ? A TYR 226 
175 1 Y 1 A ARG 226 ? A ARG 227 
176 1 Y 1 A ILE 227 ? A ILE 228 
177 1 Y 1 A GLY 228 ? A GLY 229 
178 1 Y 1 A ASP 229 ? A ASP 230 
179 1 Y 1 A LEU 230 ? A LEU 231 
180 1 Y 1 A GLN 231 ? A GLN 232 
181 1 Y 1 A ALA 232 ? A ALA 233 
182 1 Y 1 A PHE 233 ? A PHE 234 
183 1 Y 1 A GLN 234 ? A GLN 235 
184 1 Y 1 A GLY 235 ? A GLY 236 
185 1 Y 1 A HIS 236 ? A HIS 237 
186 1 Y 1 A GLY 237 ? A GLY 238 
187 1 Y 1 A ALA 238 ? A ALA 239 
188 1 Y 1 A GLY 239 ? A GLY 240 
189 1 Y 1 A ASN 240 ? A ASN 241 
190 1 Y 1 A LEU 241 ? A LEU 242 
191 1 Y 1 A ALA 242 ? A ALA 243 
192 1 Y 1 A GLY 243 ? A GLY 244 
193 1 Y 1 A LEU 244 ? A LEU 245 
194 1 Y 1 A LYS 245 ? A LYS 246 
195 1 Y 1 A GLY 246 ? A GLY 247 
196 1 Y 1 A ARG 247 ? A ARG 248 
197 1 Y 1 A LEU 248 ? A LEU 249 
198 1 Y 1 A ASP 249 ? A ASP 250 
199 1 Y 1 A TYR 250 ? A TYR 251 
200 1 Y 1 A LEU 251 ? A LEU 252 
201 1 Y 1 A SER 252 ? A SER 253 
202 1 Y 1 A SER 253 ? A SER 254 
203 1 Y 1 A LEU 254 ? A LEU 255 
204 1 Y 1 A LYS 255 ? A LYS 256 
205 1 Y 1 A VAL 256 ? A VAL 257 
206 1 Y 1 A LYS 257 ? A LYS 258 
207 1 Y 1 A GLY 258 ? A GLY 259 
208 1 Y 1 A LEU 259 ? A LEU 260 
209 1 Y 1 A VAL 260 ? A VAL 261 
210 1 Y 1 A LEU 261 ? A LEU 262 
211 1 Y 1 A GLY 262 ? A GLY 263 
212 1 Y 1 A PRO 263 ? A PRO 264 
213 1 Y 1 A ILE 264 ? A ILE 265 
214 1 Y 1 A HIS 265 ? A HIS 266 
215 1 Y 1 A LYS 266 ? A LYS 267 
216 1 Y 1 A ASN 267 ? A ASN 268 
217 1 Y 1 A GLN 268 ? A GLN 269 
218 1 Y 1 A LYS 269 ? A LYS 270 
219 1 Y 1 A ASP 270 ? A ASP 271 
220 1 Y 1 A ASP 271 ? A ASP 272 
221 1 Y 1 A VAL 272 ? A VAL 273 
222 1 Y 1 A ALA 273 ? A ALA 274 
223 1 Y 1 A GLN 274 ? A GLN 275 
224 1 Y 1 A THR 275 ? A THR 276 
225 1 Y 1 A ASP 276 ? A ASP 277 
226 1 Y 1 A LEU 277 ? A LEU 278 
227 1 Y 1 A LEU 278 ? A LEU 279 
228 1 Y 1 A GLN 279 ? A GLN 280 
229 1 Y 1 A ILE 280 ? A ILE 281 
230 1 Y 1 A ASP 281 ? A ASP 282 
231 1 Y 1 A PRO 282 ? A PRO 283 
232 1 Y 1 A ASN 283 ? A ASN 284 
233 1 Y 1 A PHE 284 ? A PHE 285 
234 1 Y 1 A GLY 285 ? A GLY 286 
235 1 Y 1 A SER 286 ? A SER 287 
236 1 Y 1 A LYS 287 ? A LYS 288 
237 1 Y 1 A GLU 288 ? A GLU 289 
238 1 Y 1 A ASP 289 ? A ASP 290 
239 1 Y 1 A PHE 290 ? A PHE 291 
240 1 Y 1 A ASP 291 ? A ASP 292 
241 1 Y 1 A SER 292 ? A SER 293 
242 1 Y 1 A LEU 293 ? A LEU 294 
243 1 Y 1 A LEU 294 ? A LEU 295 
244 1 Y 1 A GLN 295 ? A GLN 296 
245 1 Y 1 A SER 296 ? A SER 297 
246 1 Y 1 A ALA 297 ? A ALA 298 
247 1 Y 1 A LYS 298 ? A LYS 299 
248 1 Y 1 A LYS 299 ? A LYS 300 
249 1 Y 1 A LYS 300 ? A LYS 301 
250 1 Y 1 A SER 301 ? A SER 302 
251 1 Y 1 A ILE 302 ? A ILE 303 
252 1 Y 1 A ARG 303 ? A ARG 304 
253 1 Y 1 A VAL 304 ? A VAL 305 
254 1 Y 1 A ILE 305 ? A ILE 306 
255 1 Y 1 A LEU 306 ? A LEU 307 
256 1 Y 1 A ASP 307 ? A ASP 308 
257 1 Y 1 A LEU 308 ? A LEU 309 
258 1 Y 1 A THR 309 ? A THR 310 
259 1 Y 1 A PRO 310 ? A PRO 311 
260 1 Y 1 A ASN 311 ? A ASN 312 
261 1 Y 1 A TYR 312 ? A TYR 313 
262 1 Y 1 A ARG 313 ? A ARG 314 
263 1 Y 1 A GLY 314 ? A GLY 315 
264 1 Y 1 A GLU 315 ? A GLU 316 
265 1 Y 1 A ASN 316 ? A ASN 317 
266 1 Y 1 A SER 317 ? A SER 318 
267 1 Y 1 A TRP 318 ? A TRP 319 
268 1 Y 1 A PHE 319 ? A PHE 320 
269 1 Y 1 A SER 320 ? A SER 321 
270 1 Y 1 A THR 321 ? A THR 322 
271 1 Y 1 A GLN 322 ? A GLN 323 
272 1 Y 1 A VAL 323 ? A VAL 324 
273 1 Y 1 A ASP 324 ? A ASP 325 
274 1 Y 1 A THR 325 ? A THR 326 
275 1 Y 1 A VAL 326 ? A VAL 327 
276 1 Y 1 A ALA 327 ? A ALA 328 
277 1 Y 1 A THR 328 ? A THR 329 
278 1 Y 1 A LYS 329 ? A LYS 330 
279 1 Y 1 A VAL 330 ? A VAL 331 
280 1 Y 1 A LYS 331 ? A LYS 332 
281 1 Y 1 A ASP 332 ? A ASP 333 
282 1 Y 1 A ALA 333 ? A ALA 334 
283 1 Y 1 A LEU 334 ? A LEU 335 
284 1 Y 1 A GLU 335 ? A GLU 336 
285 1 Y 1 A PHE 336 ? A PHE 337 
286 1 Y 1 A TRP 337 ? A TRP 338 
287 1 Y 1 A LEU 338 ? A LEU 339 
288 1 Y 1 A GLN 339 ? A GLN 340 
289 1 Y 1 A ALA 340 ? A ALA 341 
290 1 Y 1 A GLY 341 ? A GLY 342 
291 1 Y 1 A VAL 342 ? A VAL 343 
292 1 Y 1 A ASP 343 ? A ASP 344 
293 1 Y 1 A GLY 344 ? A GLY 345 
294 1 Y 1 A PHE 345 ? A PHE 346 
295 1 Y 1 A GLN 346 ? A GLN 347 
296 1 Y 1 A VAL 347 ? A VAL 348 
297 1 Y 1 A ARG 348 ? A ARG 349 
298 1 Y 1 A ASP 349 ? A ASP 350 
299 1 Y 1 A ILE 350 ? A ILE 351 
300 1 Y 1 A GLU 351 ? A GLU 352 
301 1 Y 1 A ASN 352 ? A ASN 353 
302 1 Y 1 A LEU 353 ? A LEU 354 
303 1 Y 1 A LYS 354 ? A LYS 355 
304 1 Y 1 A ASP 355 ? A ASP 356 
305 1 Y 1 A ALA 356 ? A ALA 357 
306 1 Y 1 A SER 357 ? A SER 358 
307 1 Y 1 A SER 358 ? A SER 359 
308 1 Y 1 A PHE 359 ? A PHE 360 
309 1 Y 1 A LEU 360 ? A LEU 361 
310 1 Y 1 A ALA 361 ? A ALA 362 
311 1 Y 1 A GLU 362 ? A GLU 363 
312 1 Y 1 A TRP 363 ? A TRP 364 
313 1 Y 1 A GLN 364 ? A GLN 365 
314 1 Y 1 A ASN 365 ? A ASN 366 
315 1 Y 1 A ILE 366 ? A ILE 367 
316 1 Y 1 A THR 367 ? A THR 368 
317 1 Y 1 A LYS 368 ? A LYS 369 
318 1 Y 1 A GLY 369 ? A GLY 370 
319 1 Y 1 A PHE 370 ? A PHE 371 
320 1 Y 1 A SER 371 ? A SER 372 
321 1 Y 1 A GLU 372 ? A GLU 373 
322 1 Y 1 A ASP 373 ? A ASP 374 
323 1 Y 1 A ARG 374 ? A ARG 375 
324 1 Y 1 A LEU 375 ? A LEU 376 
325 1 Y 1 A LEU 376 ? A LEU 377 
326 1 Y 1 A ILE 377 ? A ILE 378 
327 1 Y 1 A ALA 378 ? A ALA 379 
328 1 Y 1 A GLY 379 ? A GLY 380 
329 1 Y 1 A THR 380 ? A THR 381 
330 1 Y 1 A ASN 381 ? A ASN 382 
331 1 Y 1 A SER 382 ? A SER 383 
332 1 Y 1 A SER 383 ? A SER 384 
333 1 Y 1 A ASP 384 ? A ASP 385 
334 1 Y 1 A LEU 385 ? A LEU 386 
335 1 Y 1 A GLN 386 ? A GLN 387 
336 1 Y 1 A GLN 387 ? A GLN 388 
337 1 Y 1 A ILE 388 ? A ILE 389 
338 1 Y 1 A LEU 389 ? A LEU 390 
339 1 Y 1 A SER 390 ? A SER 391 
340 1 Y 1 A LEU 391 ? A LEU 392 
341 1 Y 1 A LEU 392 ? A LEU 393 
342 1 Y 1 A GLU 393 ? A GLU 394 
343 1 Y 1 A SER 394 ? A SER 395 
344 1 Y 1 A ASN 395 ? A ASN 396 
345 1 Y 1 A LYS 396 ? A LYS 397 
346 1 Y 1 A ASP 397 ? A ASP 398 
347 1 Y 1 A LEU 398 ? A LEU 399 
348 1 Y 1 A LEU 399 ? A LEU 400 
349 1 Y 1 A LEU 400 ? A LEU 401 
350 1 Y 1 A THR 401 ? A THR 402 
351 1 Y 1 A SER 402 ? A SER 403 
352 1 Y 1 A SER 403 ? A SER 404 
353 1 Y 1 A TYR 404 ? A TYR 405 
354 1 Y 1 A LEU 405 ? A LEU 406 
355 1 Y 1 A SER 406 ? A SER 407 
356 1 Y 1 A ASP 407 ? A ASP 408 
357 1 Y 1 A SER 408 ? A SER 409 
358 1 Y 1 A GLY 409 ? A GLY 410 
359 1 Y 1 A SER 410 ? A SER 411 
360 1 Y 1 A THR 411 ? A THR 412 
361 1 Y 1 A GLY 412 ? A GLY 413 
362 1 Y 1 A GLU 413 ? A GLU 414 
363 1 Y 1 A HIS 414 ? A HIS 415 
364 1 Y 1 A THR 415 ? A THR 416 
365 1 Y 1 A LYS 416 ? A LYS 417 
366 1 Y 1 A SER 417 ? A SER 418 
367 1 Y 1 A LEU 418 ? A LEU 419 
368 1 Y 1 A VAL 419 ? A VAL 420 
369 1 Y 1 A THR 420 ? A THR 421 
370 1 Y 1 A GLN 421 ? A GLN 422 
371 1 Y 1 A TYR 422 ? A TYR 423 
372 1 Y 1 A LEU 423 ? A LEU 424 
373 1 Y 1 A ASN 424 ? A ASN 425 
374 1 Y 1 A ALA 425 ? A ALA 426 
375 1 Y 1 A THR 426 ? A THR 427 
376 1 Y 1 A GLY 427 ? A GLY 428 
377 1 Y 1 A ASN 428 ? A ASN 429 
378 1 Y 1 A ARG 429 ? A ARG 430 
379 1 Y 1 A TRP 430 ? A TRP 431 
380 1 Y 1 A CYS 431 ? A CYS 432 
381 1 Y 1 A SER 432 ? A SER 433 
382 1 Y 1 A TRP 433 ? A TRP 434 
383 1 Y 1 A SER 434 ? A SER 435 
384 1 Y 1 A LEU 435 ? A LEU 436 
385 1 Y 1 A SER 436 ? A SER 437 
386 1 Y 1 A GLN 437 ? A GLN 438 
387 1 Y 1 A ALA 438 ? A ALA 439 
388 1 Y 1 A ARG 439 ? A ARG 440 
389 1 Y 1 A LEU 440 ? A LEU 441 
390 1 Y 1 A LEU 441 ? A LEU 442 
391 1 Y 1 A THR 442 ? A THR 443 
392 1 Y 1 A SER 443 ? A SER 444 
393 1 Y 1 A PHE 444 ? A PHE 445 
394 1 Y 1 A LEU 445 ? A LEU 446 
395 1 Y 1 A PRO 446 ? A PRO 447 
396 1 Y 1 A ALA 447 ? A ALA 448 
397 1 Y 1 A GLN 448 ? A GLN 449 
398 1 Y 1 A LEU 449 ? A LEU 450 
399 1 Y 1 A LEU 450 ? A LEU 451 
400 1 Y 1 A ARG 451 ? A ARG 452 
401 1 Y 1 A LEU 452 ? A LEU 453 
402 1 Y 1 A TYR 453 ? A TYR 454 
403 1 Y 1 A GLN 454 ? A GLN 455 
404 1 Y 1 A LEU 455 ? A LEU 456 
405 1 Y 1 A MET 456 ? A MET 457 
406 1 Y 1 A LEU 457 ? A LEU 458 
407 1 Y 1 A PHE 458 ? A PHE 459 
408 1 Y 1 A THR 459 ? A THR 460 
409 1 Y 1 A LEU 460 ? A LEU 461 
410 1 Y 1 A PRO 461 ? A PRO 462 
411 1 Y 1 A GLY 462 ? A GLY 463 
412 1 Y 1 A THR 463 ? A THR 464 
413 1 Y 1 A PRO 464 ? A PRO 465 
414 1 Y 1 A VAL 465 ? A VAL 466 
415 1 Y 1 A PHE 466 ? A PHE 467 
416 1 Y 1 A SER 467 ? A SER 468 
417 1 Y 1 A TYR 468 ? A TYR 469 
418 1 Y 1 A GLY 469 ? A GLY 470 
419 1 Y 1 A ASP 470 ? A ASP 471 
420 1 Y 1 A GLU 471 ? A GLU 472 
421 1 Y 1 A ILE 472 ? A ILE 473 
422 1 Y 1 A GLY 473 ? A GLY 474 
423 1 Y 1 A LEU 474 ? A LEU 475 
424 1 Y 1 A ASP 475 ? A ASP 476 
425 1 Y 1 A ALA 476 ? A ALA 477 
426 1 Y 1 A ALA 477 ? A ALA 478 
427 1 Y 1 A ALA 478 ? A ALA 479 
428 1 Y 1 A LEU 479 ? A LEU 480 
429 1 Y 1 A PRO 480 ? A PRO 481 
430 1 Y 1 A GLY 481 ? A GLY 482 
431 1 Y 1 A GLN 482 ? A GLN 483 
432 1 Y 1 A PRO 483 ? A PRO 484 
433 1 Y 1 A MET 484 ? A MET 485 
434 1 Y 1 A GLU 485 ? A GLU 486 
435 1 Y 1 A ALA 486 ? A ALA 487 
436 1 Y 1 A PRO 487 ? A PRO 488 
437 1 Y 1 A VAL 488 ? A VAL 489 
438 1 Y 1 A MET 489 ? A MET 490 
439 1 Y 1 A LEU 490 ? A LEU 491 
440 1 Y 1 A TRP 491 ? A TRP 492 
441 1 Y 1 A ASP 492 ? A ASP 493 
442 1 Y 1 A GLU 493 ? A GLU 494 
443 1 Y 1 A SER 494 ? A SER 495 
444 1 Y 1 A SER 495 ? A SER 496 
445 1 Y 1 A PHE 496 ? A PHE 497 
446 1 Y 1 A PRO 497 ? A PRO 498 
447 1 Y 1 A ASP 498 ? A ASP 499 
448 1 Y 1 A ILE 499 ? A ILE 500 
449 1 Y 1 A PRO 500 ? A PRO 501 
450 1 Y 1 A GLY 501 ? A GLY 502 
451 1 Y 1 A ALA 502 ? A ALA 503 
452 1 Y 1 A VAL 503 ? A VAL 504 
453 1 Y 1 A SER 504 ? A SER 505 
454 1 Y 1 A ALA 505 ? A ALA 506 
455 1 Y 1 A ASN 506 ? A ASN 507 
456 1 Y 1 A MET 507 ? A MET 508 
457 1 Y 1 A THR 508 ? A THR 509 
458 1 Y 1 A VAL 509 ? A VAL 510 
459 1 Y 1 A LYS 510 ? A LYS 511 
460 1 Y 1 A GLY 511 ? A GLY 512 
461 1 Y 1 A GLN 512 ? A GLN 513 
462 1 Y 1 A SER 513 ? A SER 514 
463 1 Y 1 A GLU 514 ? A GLU 515 
464 1 Y 1 A ASP 515 ? A ASP 516 
465 1 Y 1 A PRO 516 ? A PRO 517 
466 1 Y 1 A GLY 517 ? A GLY 518 
467 1 Y 1 A SER 518 ? A SER 519 
468 1 Y 1 A LEU 519 ? A LEU 520 
469 1 Y 1 A LEU 520 ? A LEU 521 
470 1 Y 1 A SER 521 ? A SER 522 
471 1 Y 1 A LEU 522 ? A LEU 523 
472 1 Y 1 A PHE 523 ? A PHE 524 
473 1 Y 1 A ARG 524 ? A ARG 525 
474 1 Y 1 A ARG 525 ? A ARG 526 
475 1 Y 1 A LEU 526 ? A LEU 527 
476 1 Y 1 A SER 527 ? A SER 528 
477 1 Y 1 A ASP 528 ? A ASP 529 
478 1 Y 1 A GLN 529 ? A GLN 530 
479 1 Y 1 A ARG 530 ? A ARG 531 
480 1 Y 1 A SER 531 ? A SER 532 
481 1 Y 1 A LYS 532 ? A LYS 533 
482 1 Y 1 A GLU 533 ? A GLU 534 
483 1 Y 1 A ARG 534 ? A ARG 535 
484 1 Y 1 A SER 535 ? A SER 536 
485 1 Y 1 A LEU 536 ? A LEU 537 
486 1 Y 1 A LEU 537 ? A LEU 538 
487 1 Y 1 A HIS 538 ? A HIS 539 
488 1 Y 1 A GLY 539 ? A GLY 540 
489 1 Y 1 A ASP 540 ? A ASP 541 
490 1 Y 1 A PHE 541 ? A PHE 542 
491 1 Y 1 A HIS 542 ? A HIS 543 
492 1 Y 1 A ALA 543 ? A ALA 544 
493 1 Y 1 A PHE 544 ? A PHE 545 
494 1 Y 1 A SER 545 ? A SER 546 
495 1 Y 1 A ALA 546 ? A ALA 547 
496 1 Y 1 A GLY 547 ? A GLY 548 
497 1 Y 1 A PRO 548 ? A PRO 549 
498 1 Y 1 A GLY 549 ? A GLY 550 
499 1 Y 1 A LEU 550 ? A LEU 551 
500 1 Y 1 A PHE 551 ? A PHE 552 
501 1 Y 1 A SER 552 ? A SER 553 
502 1 Y 1 A TYR 553 ? A TYR 554 
503 1 Y 1 A ILE 554 ? A ILE 555 
504 1 Y 1 A ARG 555 ? A ARG 556 
505 1 Y 1 A HIS 556 ? A HIS 557 
506 1 Y 1 A TRP 557 ? A TRP 558 
507 1 Y 1 A ASP 558 ? A ASP 559 
508 1 Y 1 A GLN 559 ? A GLN 560 
509 1 Y 1 A ASN 560 ? A ASN 561 
510 1 Y 1 A GLU 561 ? A GLU 562 
511 1 Y 1 A ARG 562 ? A ARG 563 
512 1 Y 1 A PHE 563 ? A PHE 564 
513 1 Y 1 A LEU 564 ? A LEU 565 
514 1 Y 1 A VAL 565 ? A VAL 566 
515 1 Y 1 A VAL 566 ? A VAL 567 
516 1 Y 1 A LEU 567 ? A LEU 568 
517 1 Y 1 A ASN 568 ? A ASN 569 
518 1 Y 1 A PHE 569 ? A PHE 570 
519 1 Y 1 A GLY 570 ? A GLY 571 
520 1 Y 1 A ASP 571 ? A ASP 572 
521 1 Y 1 A VAL 572 ? A VAL 573 
522 1 Y 1 A GLY 573 ? A GLY 574 
523 1 Y 1 A LEU 574 ? A LEU 575 
524 1 Y 1 A SER 575 ? A SER 576 
525 1 Y 1 A ALA 576 ? A ALA 577 
526 1 Y 1 A GLY 577 ? A GLY 578 
527 1 Y 1 A LEU 578 ? A LEU 579 
528 1 Y 1 A GLN 579 ? A GLN 580 
529 1 Y 1 A ALA 580 ? A ALA 581 
530 1 Y 1 A SER 581 ? A SER 582 
531 1 Y 1 A ASP 582 ? A ASP 583 
532 1 Y 1 A LEU 583 ? A LEU 584 
533 1 Y 1 A PRO 584 ? A PRO 585 
534 1 Y 1 A ALA 585 ? A ALA 586 
535 1 Y 1 A SER 586 ? A SER 587 
536 1 Y 1 A ALA 587 ? A ALA 588 
537 1 Y 1 A SER 588 ? A SER 589 
538 1 Y 1 A LEU 589 ? A LEU 590 
539 1 Y 1 A PRO 590 ? A PRO 591 
540 1 Y 1 A ALA 591 ? A ALA 592 
541 1 Y 1 A LYS 592 ? A LYS 593 
542 1 Y 1 A ALA 593 ? A ALA 594 
543 1 Y 1 A ASP 594 ? A ASP 595 
544 1 Y 1 A LEU 595 ? A LEU 596 
545 1 Y 1 A LEU 596 ? A LEU 597 
546 1 Y 1 A LEU 597 ? A LEU 598 
547 1 Y 1 A SER 598 ? A SER 599 
548 1 Y 1 A THR 599 ? A THR 600 
549 1 Y 1 A GLN 600 ? A GLN 601 
550 1 Y 1 A PRO 601 ? A PRO 602 
551 1 Y 1 A GLY 602 ? A GLY 603 
552 1 Y 1 A ARG 603 ? A ARG 604 
553 1 Y 1 A GLU 604 ? A GLU 605 
554 1 Y 1 A GLU 605 ? A GLU 606 
555 1 Y 1 A GLY 606 ? A GLY 607 
556 1 Y 1 A SER 607 ? A SER 608 
557 1 Y 1 A PRO 608 ? A PRO 609 
558 1 Y 1 A LEU 609 ? A LEU 610 
559 1 Y 1 A GLU 610 ? A GLU 611 
560 1 Y 1 A LEU 611 ? A LEU 612 
561 1 Y 1 A GLU 612 ? A GLU 613 
562 1 Y 1 A ARG 613 ? A ARG 614 
563 1 Y 1 A LEU 614 ? A LEU 615 
564 1 Y 1 A LYS 615 ? A LYS 616 
565 1 Y 1 A LEU 616 ? A LEU 617 
566 1 Y 1 A GLU 617 ? A GLU 618 
567 1 Y 1 A PRO 618 ? A PRO 619 
568 1 Y 1 A HIS 619 ? A HIS 620 
569 1 Y 1 A GLU 620 ? A GLU 621 
570 1 Y 1 A GLY 621 ? A GLY 622 
571 1 Y 1 A LEU 622 ? A LEU 623 
572 1 Y 1 A LEU 623 ? A LEU 624 
573 1 Y 1 A LEU 624 ? A LEU 625 
574 1 Y 1 A ARG 625 ? A ARG 626 
575 1 Y 1 A PHE 626 ? A PHE 627 
576 1 Y 1 A PRO 627 ? A PRO 628 
577 1 Y 1 A TYR 628 ? A TYR 629 
578 1 Y 1 A ALA 629 ? A ALA 630 
579 1 Y 1 A ALA 630 ? A ALA 631 
580 1 Y 1 B MET 1   ? B MET 1   
581 1 Y 1 B ALA 2   ? B ALA 2   
582 1 Y 1 B GLY 3   ? B GLY 3   
583 1 Y 1 B ALA 4   ? B ALA 4   
584 1 Y 1 B GLY 5   ? B GLY 5   
585 1 Y 1 B PRO 6   ? B PRO 6   
586 1 Y 1 B LYS 7   ? B LYS 7   
587 1 Y 1 B ARG 8   ? B ARG 8   
588 1 Y 1 B ARG 9   ? B ARG 9   
589 1 Y 1 B ALA 10  ? B ALA 10  
590 1 Y 1 B LEU 11  ? B LEU 11  
591 1 Y 1 B ALA 12  ? B ALA 12  
592 1 Y 1 B ALA 13  ? B ALA 13  
593 1 Y 1 B PRO 14  ? B PRO 14  
594 1 Y 1 B ALA 15  ? B ALA 15  
595 1 Y 1 B ALA 16  ? B ALA 16  
596 1 Y 1 B GLU 17  ? B GLU 17  
597 1 Y 1 B GLU 18  ? B GLU 18  
598 1 Y 1 B LYS 19  ? B LYS 19  
599 1 Y 1 B GLU 20  ? B GLU 20  
600 1 Y 1 B GLU 21  ? B GLU 21  
601 1 Y 1 B ALA 22  ? B ALA 22  
602 1 Y 1 B ARG 23  ? B ARG 23  
603 1 Y 1 B GLU 24  ? B GLU 24  
604 1 Y 1 B LYS 25  ? B LYS 25  
605 1 Y 1 B MET 26  ? B MET 26  
606 1 Y 1 B LEU 27  ? B LEU 27  
607 1 Y 1 B ALA 28  ? B ALA 28  
608 1 Y 1 B ALA 29  ? B ALA 29  
609 1 Y 1 B LYS 30  ? B LYS 30  
610 1 Y 1 B SER 31  ? B SER 31  
611 1 Y 1 B ALA 32  ? B ALA 32  
612 1 Y 1 B ASP 33  ? B ASP 33  
613 1 Y 1 B GLY 34  ? B GLY 34  
614 1 Y 1 B SER 35  ? B SER 35  
615 1 Y 1 B ALA 36  ? B ALA 36  
616 1 Y 1 B PRO 37  ? B PRO 37  
617 1 Y 1 B ALA 38  ? B ALA 38  
618 1 Y 1 B GLY 39  ? B GLY 39  
619 1 Y 1 B GLU 40  ? B GLU 40  
620 1 Y 1 B GLY 41  ? B GLY 41  
621 1 Y 1 B GLU 42  ? B GLU 42  
622 1 Y 1 B GLY 43  ? B GLY 43  
623 1 Y 1 B VAL 44  ? B VAL 44  
624 1 Y 1 B THR 45  ? B THR 45  
625 1 Y 1 B LEU 46  ? B LEU 46  
626 1 Y 1 B GLN 47  ? B GLN 47  
627 1 Y 1 B ARG 48  ? B ARG 48  
628 1 Y 1 B ASN 49  ? B ASN 49  
629 1 Y 1 B ILE 50  ? B ILE 50  
630 1 Y 1 B ASP 223 ? B ASP 223 
631 1 Y 1 B VAL 224 ? B VAL 224 
632 1 Y 1 B SER 225 ? B SER 225 
633 1 Y 1 B ASN 226 ? B ASN 226 
634 1 Y 1 B LEU 227 ? B LEU 227 
635 1 Y 1 B ASP 228 ? B ASP 228 
636 1 Y 1 B PRO 229 ? B PRO 229 
637 1 Y 1 B ASN 230 ? B ASN 230 
638 1 Y 1 B PHE 231 ? B PHE 231 
639 1 Y 1 B SER 232 ? B SER 232 
640 1 Y 1 B ASP 508 ? B ASP 508 
641 1 Y 1 B TYR 509 ? B TYR 509 
642 1 Y 1 B LYS 510 ? B LYS 510 
643 1 Y 1 B ASP 511 ? B ASP 511 
644 1 Y 1 B ASP 512 ? B ASP 512 
645 1 Y 1 B ASP 513 ? B ASP 513 
646 1 Y 1 B ASP 514 ? B ASP 514 
647 1 Y 1 B LYS 515 ? B LYS 515 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CLR C1   C N N 74  
CLR C2   C N N 75  
CLR C3   C N S 76  
CLR C4   C N N 77  
CLR C5   C N N 78  
CLR C6   C N N 79  
CLR C7   C N N 80  
CLR C8   C N S 81  
CLR C9   C N S 82  
CLR C10  C N R 83  
CLR C11  C N N 84  
CLR C12  C N N 85  
CLR C13  C N R 86  
CLR C14  C N S 87  
CLR C15  C N N 88  
CLR C16  C N N 89  
CLR C17  C N R 90  
CLR C18  C N N 91  
CLR C19  C N N 92  
CLR C20  C N R 93  
CLR C21  C N N 94  
CLR C22  C N N 95  
CLR C23  C N N 96  
CLR C24  C N N 97  
CLR C25  C N N 98  
CLR C26  C N N 99  
CLR C27  C N N 100 
CLR O1   O N N 101 
CLR H11  H N N 102 
CLR H12  H N N 103 
CLR H21  H N N 104 
CLR H22  H N N 105 
CLR H3   H N N 106 
CLR H41  H N N 107 
CLR H42  H N N 108 
CLR H6   H N N 109 
CLR H71  H N N 110 
CLR H72  H N N 111 
CLR H8   H N N 112 
CLR H9   H N N 113 
CLR H111 H N N 114 
CLR H112 H N N 115 
CLR H121 H N N 116 
CLR H122 H N N 117 
CLR H14  H N N 118 
CLR H151 H N N 119 
CLR H152 H N N 120 
CLR H161 H N N 121 
CLR H162 H N N 122 
CLR H17  H N N 123 
CLR H181 H N N 124 
CLR H182 H N N 125 
CLR H183 H N N 126 
CLR H191 H N N 127 
CLR H192 H N N 128 
CLR H193 H N N 129 
CLR H20  H N N 130 
CLR H211 H N N 131 
CLR H212 H N N 132 
CLR H213 H N N 133 
CLR H221 H N N 134 
CLR H222 H N N 135 
CLR H231 H N N 136 
CLR H232 H N N 137 
CLR H241 H N N 138 
CLR H242 H N N 139 
CLR H25  H N N 140 
CLR H261 H N N 141 
CLR H262 H N N 142 
CLR H263 H N N 143 
CLR H271 H N N 144 
CLR H272 H N N 145 
CLR H273 H N N 146 
CLR H1   H N N 147 
CYS N    N N N 148 
CYS CA   C N R 149 
CYS C    C N N 150 
CYS O    O N N 151 
CYS CB   C N N 152 
CYS SG   S N N 153 
CYS OXT  O N N 154 
CYS H    H N N 155 
CYS H2   H N N 156 
CYS HA   H N N 157 
CYS HB2  H N N 158 
CYS HB3  H N N 159 
CYS HG   H N N 160 
CYS HXT  H N N 161 
GLN N    N N N 162 
GLN CA   C N S 163 
GLN C    C N N 164 
GLN O    O N N 165 
GLN CB   C N N 166 
GLN CG   C N N 167 
GLN CD   C N N 168 
GLN OE1  O N N 169 
GLN NE2  N N N 170 
GLN OXT  O N N 171 
GLN H    H N N 172 
GLN H2   H N N 173 
GLN HA   H N N 174 
GLN HB2  H N N 175 
GLN HB3  H N N 176 
GLN HG2  H N N 177 
GLN HG3  H N N 178 
GLN HE21 H N N 179 
GLN HE22 H N N 180 
GLN HXT  H N N 181 
GLU N    N N N 182 
GLU CA   C N S 183 
GLU C    C N N 184 
GLU O    O N N 185 
GLU CB   C N N 186 
GLU CG   C N N 187 
GLU CD   C N N 188 
GLU OE1  O N N 189 
GLU OE2  O N N 190 
GLU OXT  O N N 191 
GLU H    H N N 192 
GLU H2   H N N 193 
GLU HA   H N N 194 
GLU HB2  H N N 195 
GLU HB3  H N N 196 
GLU HG2  H N N 197 
GLU HG3  H N N 198 
GLU HE2  H N N 199 
GLU HXT  H N N 200 
GLY N    N N N 201 
GLY CA   C N N 202 
GLY C    C N N 203 
GLY O    O N N 204 
GLY OXT  O N N 205 
GLY H    H N N 206 
GLY H2   H N N 207 
GLY HA2  H N N 208 
GLY HA3  H N N 209 
GLY HXT  H N N 210 
HIS N    N N N 211 
HIS CA   C N S 212 
HIS C    C N N 213 
HIS O    O N N 214 
HIS CB   C N N 215 
HIS CG   C Y N 216 
HIS ND1  N Y N 217 
HIS CD2  C Y N 218 
HIS CE1  C Y N 219 
HIS NE2  N Y N 220 
HIS OXT  O N N 221 
HIS H    H N N 222 
HIS H2   H N N 223 
HIS HA   H N N 224 
HIS HB2  H N N 225 
HIS HB3  H N N 226 
HIS HD1  H N N 227 
HIS HD2  H N N 228 
HIS HE1  H N N 229 
HIS HE2  H N N 230 
HIS HXT  H N N 231 
ILE N    N N N 232 
ILE CA   C N S 233 
ILE C    C N N 234 
ILE O    O N N 235 
ILE CB   C N S 236 
ILE CG1  C N N 237 
ILE CG2  C N N 238 
ILE CD1  C N N 239 
ILE OXT  O N N 240 
ILE H    H N N 241 
ILE H2   H N N 242 
ILE HA   H N N 243 
ILE HB   H N N 244 
ILE HG12 H N N 245 
ILE HG13 H N N 246 
ILE HG21 H N N 247 
ILE HG22 H N N 248 
ILE HG23 H N N 249 
ILE HD11 H N N 250 
ILE HD12 H N N 251 
ILE HD13 H N N 252 
ILE HXT  H N N 253 
LBN C1   C N N 254 
LBN N1   N N N 255 
LBN P1   P N N 256 
LBN C2   C N R 257 
LBN C3   C N N 258 
LBN C4   C N N 259 
LBN C5   C N N 260 
LBN C6   C N N 261 
LBN O1   O N N 262 
LBN C7   C N N 263 
LBN C8   C N N 264 
LBN C9   C N N 265 
LBN O2   O N N 266 
LBN C10  C N N 267 
LBN C11  C N N 268 
LBN C12  C N N 269 
LBN O3   O N N 270 
LBN C13  C N N 271 
LBN C14  C N N 272 
LBN C15  C N N 273 
LBN O4   O N N 274 
LBN C16  C N N 275 
LBN C17  C N N 276 
LBN C18  C N N 277 
LBN C19  C N N 278 
LBN C20  C N N 279 
LBN C21  C N N 280 
LBN C22  C N N 281 
LBN C23  C N N 282 
LBN C24  C N N 283 
LBN C25  C N N 284 
LBN O5   O N N 285 
LBN C26  C N N 286 
LBN O6   O N N 287 
LBN C27  C N N 288 
LBN C28  C N N 289 
LBN C29  C N N 290 
LBN C30  C N N 291 
LBN C31  C N N 292 
LBN C32  C N N 293 
LBN C33  C N N 294 
LBN C34  C N N 295 
LBN O7   O N N 296 
LBN C35  C N N 297 
LBN O8   O N N 298 
LBN C36  C N N 299 
LBN C37  C N N 300 
LBN C38  C N N 301 
LBN C39  C N N 302 
LBN C40  C N N 303 
LBN C41  C N N 304 
LBN C42  C N N 305 
LBN H1   H N N 306 
LBN H2   H N N 307 
LBN H3   H N N 308 
LBN H4   H N N 309 
LBN H5   H N N 310 
LBN H6   H N N 311 
LBN H7   H N N 312 
LBN H8   H N N 313 
LBN H9   H N N 314 
LBN H10  H N N 315 
LBN H11  H N N 316 
LBN H12  H N N 317 
LBN H13  H N N 318 
LBN H14  H N N 319 
LBN H15  H N N 320 
LBN H16  H N N 321 
LBN H17  H N N 322 
LBN H18  H N N 323 
LBN H19  H N N 324 
LBN H20  H N N 325 
LBN H21  H N N 326 
LBN H22  H N N 327 
LBN H23  H N N 328 
LBN H24  H N N 329 
LBN H25  H N N 330 
LBN H26  H N N 331 
LBN H27  H N N 332 
LBN H28  H N N 333 
LBN H30  H N N 334 
LBN H31  H N N 335 
LBN H32  H N N 336 
LBN H33  H N N 337 
LBN H34  H N N 338 
LBN H35  H N N 339 
LBN H36  H N N 340 
LBN H37  H N N 341 
LBN H38  H N N 342 
LBN H39  H N N 343 
LBN H40  H N N 344 
LBN H41  H N N 345 
LBN H42  H N N 346 
LBN H43  H N N 347 
LBN H44  H N N 348 
LBN H45  H N N 349 
LBN H46  H N N 350 
LBN H47  H N N 351 
LBN H48  H N N 352 
LBN H49  H N N 353 
LBN H50  H N N 354 
LBN H51  H N N 355 
LBN H52  H N N 356 
LBN H53  H N N 357 
LBN H54  H N N 358 
LBN H55  H N N 359 
LBN H56  H N N 360 
LBN H57  H N N 361 
LBN H58  H N N 362 
LBN H59  H N N 363 
LBN H60  H N N 364 
LBN H61  H N N 365 
LBN H62  H N N 366 
LBN H63  H N N 367 
LBN H64  H N N 368 
LBN H65  H N N 369 
LBN H66  H N N 370 
LBN H67  H N N 371 
LBN H68  H N N 372 
LBN H69  H N N 373 
LBN H70  H N N 374 
LBN H71  H N N 375 
LBN H72  H N N 376 
LBN H73  H N N 377 
LBN H74  H N N 378 
LBN H75  H N N 379 
LBN H76  H N N 380 
LBN H77  H N N 381 
LBN H78  H N N 382 
LBN H79  H N N 383 
LBN H80  H N N 384 
LBN H81  H N N 385 
LBN H82  H N N 386 
LBN H83  H N N 387 
LEU N    N N N 388 
LEU CA   C N S 389 
LEU C    C N N 390 
LEU O    O N N 391 
LEU CB   C N N 392 
LEU CG   C N N 393 
LEU CD1  C N N 394 
LEU CD2  C N N 395 
LEU OXT  O N N 396 
LEU H    H N N 397 
LEU H2   H N N 398 
LEU HA   H N N 399 
LEU HB2  H N N 400 
LEU HB3  H N N 401 
LEU HG   H N N 402 
LEU HD11 H N N 403 
LEU HD12 H N N 404 
LEU HD13 H N N 405 
LEU HD21 H N N 406 
LEU HD22 H N N 407 
LEU HD23 H N N 408 
LEU HXT  H N N 409 
LYS N    N N N 410 
LYS CA   C N S 411 
LYS C    C N N 412 
LYS O    O N N 413 
LYS CB   C N N 414 
LYS CG   C N N 415 
LYS CD   C N N 416 
LYS CE   C N N 417 
LYS NZ   N N N 418 
LYS OXT  O N N 419 
LYS H    H N N 420 
LYS H2   H N N 421 
LYS HA   H N N 422 
LYS HB2  H N N 423 
LYS HB3  H N N 424 
LYS HG2  H N N 425 
LYS HG3  H N N 426 
LYS HD2  H N N 427 
LYS HD3  H N N 428 
LYS HE2  H N N 429 
LYS HE3  H N N 430 
LYS HZ1  H N N 431 
LYS HZ2  H N N 432 
LYS HZ3  H N N 433 
LYS HXT  H N N 434 
MET N    N N N 435 
MET CA   C N S 436 
MET C    C N N 437 
MET O    O N N 438 
MET CB   C N N 439 
MET CG   C N N 440 
MET SD   S N N 441 
MET CE   C N N 442 
MET OXT  O N N 443 
MET H    H N N 444 
MET H2   H N N 445 
MET HA   H N N 446 
MET HB2  H N N 447 
MET HB3  H N N 448 
MET HG2  H N N 449 
MET HG3  H N N 450 
MET HE1  H N N 451 
MET HE2  H N N 452 
MET HE3  H N N 453 
MET HXT  H N N 454 
PHE N    N N N 455 
PHE CA   C N S 456 
PHE C    C N N 457 
PHE O    O N N 458 
PHE CB   C N N 459 
PHE CG   C Y N 460 
PHE CD1  C Y N 461 
PHE CD2  C Y N 462 
PHE CE1  C Y N 463 
PHE CE2  C Y N 464 
PHE CZ   C Y N 465 
PHE OXT  O N N 466 
PHE H    H N N 467 
PHE H2   H N N 468 
PHE HA   H N N 469 
PHE HB2  H N N 470 
PHE HB3  H N N 471 
PHE HD1  H N N 472 
PHE HD2  H N N 473 
PHE HE1  H N N 474 
PHE HE2  H N N 475 
PHE HZ   H N N 476 
PHE HXT  H N N 477 
PRO N    N N N 478 
PRO CA   C N S 479 
PRO C    C N N 480 
PRO O    O N N 481 
PRO CB   C N N 482 
PRO CG   C N N 483 
PRO CD   C N N 484 
PRO OXT  O N N 485 
PRO H    H N N 486 
PRO HA   H N N 487 
PRO HB2  H N N 488 
PRO HB3  H N N 489 
PRO HG2  H N N 490 
PRO HG3  H N N 491 
PRO HD2  H N N 492 
PRO HD3  H N N 493 
PRO HXT  H N N 494 
SER N    N N N 495 
SER CA   C N S 496 
SER C    C N N 497 
SER O    O N N 498 
SER CB   C N N 499 
SER OG   O N N 500 
SER OXT  O N N 501 
SER H    H N N 502 
SER H2   H N N 503 
SER HA   H N N 504 
SER HB2  H N N 505 
SER HB3  H N N 506 
SER HG   H N N 507 
SER HXT  H N N 508 
THR N    N N N 509 
THR CA   C N S 510 
THR C    C N N 511 
THR O    O N N 512 
THR CB   C N R 513 
THR OG1  O N N 514 
THR CG2  C N N 515 
THR OXT  O N N 516 
THR H    H N N 517 
THR H2   H N N 518 
THR HA   H N N 519 
THR HB   H N N 520 
THR HG1  H N N 521 
THR HG21 H N N 522 
THR HG22 H N N 523 
THR HG23 H N N 524 
THR HXT  H N N 525 
TRP N    N N N 526 
TRP CA   C N S 527 
TRP C    C N N 528 
TRP O    O N N 529 
TRP CB   C N N 530 
TRP CG   C Y N 531 
TRP CD1  C Y N 532 
TRP CD2  C Y N 533 
TRP NE1  N Y N 534 
TRP CE2  C Y N 535 
TRP CE3  C Y N 536 
TRP CZ2  C Y N 537 
TRP CZ3  C Y N 538 
TRP CH2  C Y N 539 
TRP OXT  O N N 540 
TRP H    H N N 541 
TRP H2   H N N 542 
TRP HA   H N N 543 
TRP HB2  H N N 544 
TRP HB3  H N N 545 
TRP HD1  H N N 546 
TRP HE1  H N N 547 
TRP HE3  H N N 548 
TRP HZ2  H N N 549 
TRP HZ3  H N N 550 
TRP HH2  H N N 551 
TRP HXT  H N N 552 
TYR N    N N N 553 
TYR CA   C N S 554 
TYR C    C N N 555 
TYR O    O N N 556 
TYR CB   C N N 557 
TYR CG   C Y N 558 
TYR CD1  C Y N 559 
TYR CD2  C Y N 560 
TYR CE1  C Y N 561 
TYR CE2  C Y N 562 
TYR CZ   C Y N 563 
TYR OH   O N N 564 
TYR OXT  O N N 565 
TYR H    H N N 566 
TYR H2   H N N 567 
TYR HA   H N N 568 
TYR HB2  H N N 569 
TYR HB3  H N N 570 
TYR HD1  H N N 571 
TYR HD2  H N N 572 
TYR HE1  H N N 573 
TYR HE2  H N N 574 
TYR HH   H N N 575 
TYR HXT  H N N 576 
VAL N    N N N 577 
VAL CA   C N S 578 
VAL C    C N N 579 
VAL O    O N N 580 
VAL CB   C N N 581 
VAL CG1  C N N 582 
VAL CG2  C N N 583 
VAL OXT  O N N 584 
VAL H    H N N 585 
VAL H2   H N N 586 
VAL HA   H N N 587 
VAL HB   H N N 588 
VAL HG11 H N N 589 
VAL HG12 H N N 590 
VAL HG13 H N N 591 
VAL HG21 H N N 592 
VAL HG22 H N N 593 
VAL HG23 H N N 594 
VAL HXT  H N N 595 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CLR C1  C2   sing N N 70  
CLR C1  C10  sing N N 71  
CLR C1  H11  sing N N 72  
CLR C1  H12  sing N N 73  
CLR C2  C3   sing N N 74  
CLR C2  H21  sing N N 75  
CLR C2  H22  sing N N 76  
CLR C3  C4   sing N N 77  
CLR C3  O1   sing N N 78  
CLR C3  H3   sing N N 79  
CLR C4  C5   sing N N 80  
CLR C4  H41  sing N N 81  
CLR C4  H42  sing N N 82  
CLR C5  C6   doub N N 83  
CLR C5  C10  sing N N 84  
CLR C6  C7   sing N N 85  
CLR C6  H6   sing N N 86  
CLR C7  C8   sing N N 87  
CLR C7  H71  sing N N 88  
CLR C7  H72  sing N N 89  
CLR C8  C9   sing N N 90  
CLR C8  C14  sing N N 91  
CLR C8  H8   sing N N 92  
CLR C9  C10  sing N N 93  
CLR C9  C11  sing N N 94  
CLR C9  H9   sing N N 95  
CLR C10 C19  sing N N 96  
CLR C11 C12  sing N N 97  
CLR C11 H111 sing N N 98  
CLR C11 H112 sing N N 99  
CLR C12 C13  sing N N 100 
CLR C12 H121 sing N N 101 
CLR C12 H122 sing N N 102 
CLR C13 C14  sing N N 103 
CLR C13 C17  sing N N 104 
CLR C13 C18  sing N N 105 
CLR C14 C15  sing N N 106 
CLR C14 H14  sing N N 107 
CLR C15 C16  sing N N 108 
CLR C15 H151 sing N N 109 
CLR C15 H152 sing N N 110 
CLR C16 C17  sing N N 111 
CLR C16 H161 sing N N 112 
CLR C16 H162 sing N N 113 
CLR C17 C20  sing N N 114 
CLR C17 H17  sing N N 115 
CLR C18 H181 sing N N 116 
CLR C18 H182 sing N N 117 
CLR C18 H183 sing N N 118 
CLR C19 H191 sing N N 119 
CLR C19 H192 sing N N 120 
CLR C19 H193 sing N N 121 
CLR C20 C21  sing N N 122 
CLR C20 C22  sing N N 123 
CLR C20 H20  sing N N 124 
CLR C21 H211 sing N N 125 
CLR C21 H212 sing N N 126 
CLR C21 H213 sing N N 127 
CLR C22 C23  sing N N 128 
CLR C22 H221 sing N N 129 
CLR C22 H222 sing N N 130 
CLR C23 C24  sing N N 131 
CLR C23 H231 sing N N 132 
CLR C23 H232 sing N N 133 
CLR C24 C25  sing N N 134 
CLR C24 H241 sing N N 135 
CLR C24 H242 sing N N 136 
CLR C25 C26  sing N N 137 
CLR C25 C27  sing N N 138 
CLR C25 H25  sing N N 139 
CLR C26 H261 sing N N 140 
CLR C26 H262 sing N N 141 
CLR C26 H263 sing N N 142 
CLR C27 H271 sing N N 143 
CLR C27 H272 sing N N 144 
CLR C27 H273 sing N N 145 
CLR O1  H1   sing N N 146 
CYS N   CA   sing N N 147 
CYS N   H    sing N N 148 
CYS N   H2   sing N N 149 
CYS CA  C    sing N N 150 
CYS CA  CB   sing N N 151 
CYS CA  HA   sing N N 152 
CYS C   O    doub N N 153 
CYS C   OXT  sing N N 154 
CYS CB  SG   sing N N 155 
CYS CB  HB2  sing N N 156 
CYS CB  HB3  sing N N 157 
CYS SG  HG   sing N N 158 
CYS OXT HXT  sing N N 159 
GLN N   CA   sing N N 160 
GLN N   H    sing N N 161 
GLN N   H2   sing N N 162 
GLN CA  C    sing N N 163 
GLN CA  CB   sing N N 164 
GLN CA  HA   sing N N 165 
GLN C   O    doub N N 166 
GLN C   OXT  sing N N 167 
GLN CB  CG   sing N N 168 
GLN CB  HB2  sing N N 169 
GLN CB  HB3  sing N N 170 
GLN CG  CD   sing N N 171 
GLN CG  HG2  sing N N 172 
GLN CG  HG3  sing N N 173 
GLN CD  OE1  doub N N 174 
GLN CD  NE2  sing N N 175 
GLN NE2 HE21 sing N N 176 
GLN NE2 HE22 sing N N 177 
GLN OXT HXT  sing N N 178 
GLU N   CA   sing N N 179 
GLU N   H    sing N N 180 
GLU N   H2   sing N N 181 
GLU CA  C    sing N N 182 
GLU CA  CB   sing N N 183 
GLU CA  HA   sing N N 184 
GLU C   O    doub N N 185 
GLU C   OXT  sing N N 186 
GLU CB  CG   sing N N 187 
GLU CB  HB2  sing N N 188 
GLU CB  HB3  sing N N 189 
GLU CG  CD   sing N N 190 
GLU CG  HG2  sing N N 191 
GLU CG  HG3  sing N N 192 
GLU CD  OE1  doub N N 193 
GLU CD  OE2  sing N N 194 
GLU OE2 HE2  sing N N 195 
GLU OXT HXT  sing N N 196 
GLY N   CA   sing N N 197 
GLY N   H    sing N N 198 
GLY N   H2   sing N N 199 
GLY CA  C    sing N N 200 
GLY CA  HA2  sing N N 201 
GLY CA  HA3  sing N N 202 
GLY C   O    doub N N 203 
GLY C   OXT  sing N N 204 
GLY OXT HXT  sing N N 205 
HIS N   CA   sing N N 206 
HIS N   H    sing N N 207 
HIS N   H2   sing N N 208 
HIS CA  C    sing N N 209 
HIS CA  CB   sing N N 210 
HIS CA  HA   sing N N 211 
HIS C   O    doub N N 212 
HIS C   OXT  sing N N 213 
HIS CB  CG   sing N N 214 
HIS CB  HB2  sing N N 215 
HIS CB  HB3  sing N N 216 
HIS CG  ND1  sing Y N 217 
HIS CG  CD2  doub Y N 218 
HIS ND1 CE1  doub Y N 219 
HIS ND1 HD1  sing N N 220 
HIS CD2 NE2  sing Y N 221 
HIS CD2 HD2  sing N N 222 
HIS CE1 NE2  sing Y N 223 
HIS CE1 HE1  sing N N 224 
HIS NE2 HE2  sing N N 225 
HIS OXT HXT  sing N N 226 
ILE N   CA   sing N N 227 
ILE N   H    sing N N 228 
ILE N   H2   sing N N 229 
ILE CA  C    sing N N 230 
ILE CA  CB   sing N N 231 
ILE CA  HA   sing N N 232 
ILE C   O    doub N N 233 
ILE C   OXT  sing N N 234 
ILE CB  CG1  sing N N 235 
ILE CB  CG2  sing N N 236 
ILE CB  HB   sing N N 237 
ILE CG1 CD1  sing N N 238 
ILE CG1 HG12 sing N N 239 
ILE CG1 HG13 sing N N 240 
ILE CG2 HG21 sing N N 241 
ILE CG2 HG22 sing N N 242 
ILE CG2 HG23 sing N N 243 
ILE CD1 HD11 sing N N 244 
ILE CD1 HD12 sing N N 245 
ILE CD1 HD13 sing N N 246 
ILE OXT HXT  sing N N 247 
LBN C12 N1   sing N N 248 
LBN O3  P1   sing N N 249 
LBN O2  C9   sing N N 250 
LBN O2  P1   sing N N 251 
LBN C9  C6   sing N N 252 
LBN O4  P1   doub N N 253 
LBN P1  O1   sing N N 254 
LBN C6  N1   sing N N 255 
LBN N1  C15  sing N N 256 
LBN N1  C18  sing N N 257 
LBN O1  C1   sing N N 258 
LBN C2  C1   sing N N 259 
LBN C2  C3   sing N N 260 
LBN C2  O7   sing N N 261 
LBN C3  O5   sing N N 262 
LBN O6  C25  doub N N 263 
LBN O5  C25  sing N N 264 
LBN O7  C34  sing N N 265 
LBN C25 C26  sing N N 266 
LBN C34 C35  sing N N 267 
LBN C34 O8   doub N N 268 
LBN C26 C27  sing N N 269 
LBN C35 C36  sing N N 270 
LBN C27 C28  sing N N 271 
LBN C36 C37  sing N N 272 
LBN C28 C29  sing N N 273 
LBN C37 C38  sing N N 274 
LBN C29 C30  sing N N 275 
LBN C39 C38  sing N N 276 
LBN C39 C40  sing N N 277 
LBN C41 C40  sing N N 278 
LBN C41 C42  sing N N 279 
LBN C30 C31  sing N N 280 
LBN C42 C5   doub N Z 281 
LBN C31 C32  sing N N 282 
LBN C5  C8   sing N N 283 
LBN C8  C11  sing N N 284 
LBN C32 C33  sing N N 285 
LBN C11 C14  sing N N 286 
LBN C33 C4   sing N N 287 
LBN C14 C17  sing N N 288 
LBN C4  C7   sing N N 289 
LBN C17 C20  sing N N 290 
LBN C7  C10  sing N N 291 
LBN C20 C22  sing N N 292 
LBN C10 C13  sing N N 293 
LBN C22 C23  sing N N 294 
LBN C13 C16  sing N N 295 
LBN C23 C24  sing N N 296 
LBN C16 C19  sing N N 297 
LBN C19 C21  sing N N 298 
LBN C1  H1   sing N N 299 
LBN C1  H2   sing N N 300 
LBN C2  H3   sing N N 301 
LBN C3  H4   sing N N 302 
LBN C3  H5   sing N N 303 
LBN C4  H6   sing N N 304 
LBN C4  H7   sing N N 305 
LBN C5  H8   sing N N 306 
LBN C6  H9   sing N N 307 
LBN C6  H10  sing N N 308 
LBN C7  H11  sing N N 309 
LBN C7  H12  sing N N 310 
LBN C8  H13  sing N N 311 
LBN C8  H14  sing N N 312 
LBN C9  H15  sing N N 313 
LBN C9  H16  sing N N 314 
LBN C10 H17  sing N N 315 
LBN C10 H18  sing N N 316 
LBN C11 H19  sing N N 317 
LBN C12 H20  sing N N 318 
LBN C12 H21  sing N N 319 
LBN C12 H22  sing N N 320 
LBN C13 H23  sing N N 321 
LBN C13 H24  sing N N 322 
LBN C14 H25  sing N N 323 
LBN C15 H26  sing N N 324 
LBN C15 H27  sing N N 325 
LBN C15 H28  sing N N 326 
LBN C16 H30  sing N N 327 
LBN C16 H31  sing N N 328 
LBN C17 H32  sing N N 329 
LBN C17 H33  sing N N 330 
LBN C18 H34  sing N N 331 
LBN C18 H35  sing N N 332 
LBN C18 H36  sing N N 333 
LBN C19 H37  sing N N 334 
LBN C19 H38  sing N N 335 
LBN C20 H39  sing N N 336 
LBN C20 H40  sing N N 337 
LBN C21 H41  sing N N 338 
LBN C21 H42  sing N N 339 
LBN C21 H43  sing N N 340 
LBN C22 H44  sing N N 341 
LBN C22 H45  sing N N 342 
LBN C23 H46  sing N N 343 
LBN C23 H47  sing N N 344 
LBN C24 H48  sing N N 345 
LBN C24 H49  sing N N 346 
LBN C24 H50  sing N N 347 
LBN C26 H51  sing N N 348 
LBN C26 H52  sing N N 349 
LBN C27 H53  sing N N 350 
LBN C27 H54  sing N N 351 
LBN C28 H55  sing N N 352 
LBN C28 H56  sing N N 353 
LBN C29 H57  sing N N 354 
LBN C29 H58  sing N N 355 
LBN C30 H59  sing N N 356 
LBN C30 H60  sing N N 357 
LBN C31 H61  sing N N 358 
LBN C31 H62  sing N N 359 
LBN C32 H63  sing N N 360 
LBN C32 H64  sing N N 361 
LBN C33 H65  sing N N 362 
LBN C33 H66  sing N N 363 
LBN C35 H67  sing N N 364 
LBN C35 H68  sing N N 365 
LBN C36 H69  sing N N 366 
LBN C36 H70  sing N N 367 
LBN C37 H71  sing N N 368 
LBN C37 H72  sing N N 369 
LBN C38 H73  sing N N 370 
LBN C38 H74  sing N N 371 
LBN C39 H75  sing N N 372 
LBN C40 H76  sing N N 373 
LBN C41 H77  sing N N 374 
LBN C41 H78  sing N N 375 
LBN C42 H79  sing N N 376 
LBN C11 H80  sing N N 377 
LBN C14 H81  sing N N 378 
LBN C39 H82  sing N N 379 
LBN C40 H83  sing N N 380 
LEU N   CA   sing N N 381 
LEU N   H    sing N N 382 
LEU N   H2   sing N N 383 
LEU CA  C    sing N N 384 
LEU CA  CB   sing N N 385 
LEU CA  HA   sing N N 386 
LEU C   O    doub N N 387 
LEU C   OXT  sing N N 388 
LEU CB  CG   sing N N 389 
LEU CB  HB2  sing N N 390 
LEU CB  HB3  sing N N 391 
LEU CG  CD1  sing N N 392 
LEU CG  CD2  sing N N 393 
LEU CG  HG   sing N N 394 
LEU CD1 HD11 sing N N 395 
LEU CD1 HD12 sing N N 396 
LEU CD1 HD13 sing N N 397 
LEU CD2 HD21 sing N N 398 
LEU CD2 HD22 sing N N 399 
LEU CD2 HD23 sing N N 400 
LEU OXT HXT  sing N N 401 
LYS N   CA   sing N N 402 
LYS N   H    sing N N 403 
LYS N   H2   sing N N 404 
LYS CA  C    sing N N 405 
LYS CA  CB   sing N N 406 
LYS CA  HA   sing N N 407 
LYS C   O    doub N N 408 
LYS C   OXT  sing N N 409 
LYS CB  CG   sing N N 410 
LYS CB  HB2  sing N N 411 
LYS CB  HB3  sing N N 412 
LYS CG  CD   sing N N 413 
LYS CG  HG2  sing N N 414 
LYS CG  HG3  sing N N 415 
LYS CD  CE   sing N N 416 
LYS CD  HD2  sing N N 417 
LYS CD  HD3  sing N N 418 
LYS CE  NZ   sing N N 419 
LYS CE  HE2  sing N N 420 
LYS CE  HE3  sing N N 421 
LYS NZ  HZ1  sing N N 422 
LYS NZ  HZ2  sing N N 423 
LYS NZ  HZ3  sing N N 424 
LYS OXT HXT  sing N N 425 
MET N   CA   sing N N 426 
MET N   H    sing N N 427 
MET N   H2   sing N N 428 
MET CA  C    sing N N 429 
MET CA  CB   sing N N 430 
MET CA  HA   sing N N 431 
MET C   O    doub N N 432 
MET C   OXT  sing N N 433 
MET CB  CG   sing N N 434 
MET CB  HB2  sing N N 435 
MET CB  HB3  sing N N 436 
MET CG  SD   sing N N 437 
MET CG  HG2  sing N N 438 
MET CG  HG3  sing N N 439 
MET SD  CE   sing N N 440 
MET CE  HE1  sing N N 441 
MET CE  HE2  sing N N 442 
MET CE  HE3  sing N N 443 
MET OXT HXT  sing N N 444 
PHE N   CA   sing N N 445 
PHE N   H    sing N N 446 
PHE N   H2   sing N N 447 
PHE CA  C    sing N N 448 
PHE CA  CB   sing N N 449 
PHE CA  HA   sing N N 450 
PHE C   O    doub N N 451 
PHE C   OXT  sing N N 452 
PHE CB  CG   sing N N 453 
PHE CB  HB2  sing N N 454 
PHE CB  HB3  sing N N 455 
PHE CG  CD1  doub Y N 456 
PHE CG  CD2  sing Y N 457 
PHE CD1 CE1  sing Y N 458 
PHE CD1 HD1  sing N N 459 
PHE CD2 CE2  doub Y N 460 
PHE CD2 HD2  sing N N 461 
PHE CE1 CZ   doub Y N 462 
PHE CE1 HE1  sing N N 463 
PHE CE2 CZ   sing Y N 464 
PHE CE2 HE2  sing N N 465 
PHE CZ  HZ   sing N N 466 
PHE OXT HXT  sing N N 467 
PRO N   CA   sing N N 468 
PRO N   CD   sing N N 469 
PRO N   H    sing N N 470 
PRO CA  C    sing N N 471 
PRO CA  CB   sing N N 472 
PRO CA  HA   sing N N 473 
PRO C   O    doub N N 474 
PRO C   OXT  sing N N 475 
PRO CB  CG   sing N N 476 
PRO CB  HB2  sing N N 477 
PRO CB  HB3  sing N N 478 
PRO CG  CD   sing N N 479 
PRO CG  HG2  sing N N 480 
PRO CG  HG3  sing N N 481 
PRO CD  HD2  sing N N 482 
PRO CD  HD3  sing N N 483 
PRO OXT HXT  sing N N 484 
SER N   CA   sing N N 485 
SER N   H    sing N N 486 
SER N   H2   sing N N 487 
SER CA  C    sing N N 488 
SER CA  CB   sing N N 489 
SER CA  HA   sing N N 490 
SER C   O    doub N N 491 
SER C   OXT  sing N N 492 
SER CB  OG   sing N N 493 
SER CB  HB2  sing N N 494 
SER CB  HB3  sing N N 495 
SER OG  HG   sing N N 496 
SER OXT HXT  sing N N 497 
THR N   CA   sing N N 498 
THR N   H    sing N N 499 
THR N   H2   sing N N 500 
THR CA  C    sing N N 501 
THR CA  CB   sing N N 502 
THR CA  HA   sing N N 503 
THR C   O    doub N N 504 
THR C   OXT  sing N N 505 
THR CB  OG1  sing N N 506 
THR CB  CG2  sing N N 507 
THR CB  HB   sing N N 508 
THR OG1 HG1  sing N N 509 
THR CG2 HG21 sing N N 510 
THR CG2 HG22 sing N N 511 
THR CG2 HG23 sing N N 512 
THR OXT HXT  sing N N 513 
TRP N   CA   sing N N 514 
TRP N   H    sing N N 515 
TRP N   H2   sing N N 516 
TRP CA  C    sing N N 517 
TRP CA  CB   sing N N 518 
TRP CA  HA   sing N N 519 
TRP C   O    doub N N 520 
TRP C   OXT  sing N N 521 
TRP CB  CG   sing N N 522 
TRP CB  HB2  sing N N 523 
TRP CB  HB3  sing N N 524 
TRP CG  CD1  doub Y N 525 
TRP CG  CD2  sing Y N 526 
TRP CD1 NE1  sing Y N 527 
TRP CD1 HD1  sing N N 528 
TRP CD2 CE2  doub Y N 529 
TRP CD2 CE3  sing Y N 530 
TRP NE1 CE2  sing Y N 531 
TRP NE1 HE1  sing N N 532 
TRP CE2 CZ2  sing Y N 533 
TRP CE3 CZ3  doub Y N 534 
TRP CE3 HE3  sing N N 535 
TRP CZ2 CH2  doub Y N 536 
TRP CZ2 HZ2  sing N N 537 
TRP CZ3 CH2  sing Y N 538 
TRP CZ3 HZ3  sing N N 539 
TRP CH2 HH2  sing N N 540 
TRP OXT HXT  sing N N 541 
TYR N   CA   sing N N 542 
TYR N   H    sing N N 543 
TYR N   H2   sing N N 544 
TYR CA  C    sing N N 545 
TYR CA  CB   sing N N 546 
TYR CA  HA   sing N N 547 
TYR C   O    doub N N 548 
TYR C   OXT  sing N N 549 
TYR CB  CG   sing N N 550 
TYR CB  HB2  sing N N 551 
TYR CB  HB3  sing N N 552 
TYR CG  CD1  doub Y N 553 
TYR CG  CD2  sing Y N 554 
TYR CD1 CE1  sing Y N 555 
TYR CD1 HD1  sing N N 556 
TYR CD2 CE2  doub Y N 557 
TYR CD2 HD2  sing N N 558 
TYR CE1 CZ   doub Y N 559 
TYR CE1 HE1  sing N N 560 
TYR CE2 CZ   sing Y N 561 
TYR CE2 HE2  sing N N 562 
TYR CZ  OH   sing N N 563 
TYR OH  HH   sing N N 564 
TYR OXT HXT  sing N N 565 
VAL N   CA   sing N N 566 
VAL N   H    sing N N 567 
VAL N   H2   sing N N 568 
VAL CA  C    sing N N 569 
VAL CA  CB   sing N N 570 
VAL CA  HA   sing N N 571 
VAL C   O    doub N N 572 
VAL C   OXT  sing N N 573 
VAL CB  CG1  sing N N 574 
VAL CB  CG2  sing N N 575 
VAL CB  HB   sing N N 576 
VAL CG1 HG11 sing N N 577 
VAL CG1 HG12 sing N N 578 
VAL CG1 HG13 sing N N 579 
VAL CG2 HG21 sing N N 580 
VAL CG2 HG22 sing N N 581 
VAL CG2 HG23 sing N N 582 
VAL OXT HXT  sing N N 583 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-08-09 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8KDJ 
_em_admin.last_update        2025-02-26 
_em_admin.map_release_date   2025-02-12 
_em_admin.title              'Structure of apo inward-open LAT1-CD98h in nanodisc, focused on TMD' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.173 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         51 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Max Planck Society' 
_pdbx_audit_support.country                Germany 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8KDJ 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . THR A 1 163 ? 76.277  84.882  26.019 1.00 217.32 ? 162 THR A N   1 
ATOM   2    C CA  . THR A 1 163 ? 76.559  86.092  26.846 1.00 279.70 ? 162 THR A CA  1 
ATOM   3    C C   . THR A 1 163 ? 77.938  85.957  27.496 1.00 257.17 ? 162 THR A C   1 
ATOM   4    O O   . THR A 1 163 ? 78.388  84.835  27.706 1.00 219.84 ? 162 THR A O   1 
ATOM   5    C CB  . THR A 1 163 ? 75.443  86.313  27.872 1.00 320.85 ? 162 THR A CB  1 
ATOM   6    O OG1 . THR A 1 163 ? 74.235  86.397  27.108 1.00 304.92 ? 162 THR A OG1 1 
ATOM   7    C CG2 . THR A 1 163 ? 75.607  87.552  28.735 1.00 276.27 ? 162 THR A CG2 1 
ATOM   8    N N   . GLY A 1 164 ? 78.588  87.103  27.799 1.00 233.71 ? 163 GLY A N   1 
ATOM   9    C CA  . GLY A 1 164 ? 79.983  87.174  28.222 1.00 217.93 ? 163 GLY A CA  1 
ATOM   10   C C   . GLY A 1 164 ? 80.960  86.880  27.070 1.00 259.21 ? 163 GLY A C   1 
ATOM   11   O O   . GLY A 1 164 ? 80.569  86.710  25.914 1.00 323.51 ? 163 GLY A O   1 
ATOM   12   N N   . LEU A 1 165 ? 82.259  86.819  27.379 1.00 213.08 ? 164 LEU A N   1 
ATOM   13   C CA  . LEU A 1 165 ? 83.292  86.514  26.392 1.00 213.28 ? 164 LEU A CA  1 
ATOM   14   C C   . LEU A 1 165 ? 83.242  85.018  26.036 1.00 228.18 ? 164 LEU A C   1 
ATOM   15   O O   . LEU A 1 165 ? 83.216  84.182  26.933 1.00 287.56 ? 164 LEU A O   1 
ATOM   16   C CB  . LEU A 1 165 ? 84.625  86.944  27.017 1.00 214.75 ? 164 LEU A CB  1 
ATOM   17   C CG  . LEU A 1 165 ? 85.846  86.989  26.114 1.00 255.33 ? 164 LEU A CG  1 
ATOM   18   C CD1 . LEU A 1 165 ? 85.673  88.053  25.044 1.00 329.38 ? 164 LEU A CD1 1 
ATOM   19   C CD2 . LEU A 1 165 ? 87.084  87.287  26.930 1.00 269.29 ? 164 LEU A CD2 1 
ATOM   20   N N   . SER A 1 166 ? 83.212  84.654  24.741 1.00 223.14 ? 165 SER A N   1 
ATOM   21   C CA  . SER A 1 166 ? 82.967  83.266  24.339 1.00 227.09 ? 165 SER A CA  1 
ATOM   22   C C   . SER A 1 166 ? 84.264  82.448  24.221 1.00 204.08 ? 165 SER A C   1 
ATOM   23   O O   . SER A 1 166 ? 85.373  82.996  24.220 1.00 199.63 ? 165 SER A O   1 
ATOM   24   C CB  . SER A 1 166 ? 82.172  83.213  23.053 1.00 264.10 ? 165 SER A CB  1 
ATOM   25   O OG  . SER A 1 166 ? 81.657  81.910  22.816 1.00 280.92 ? 165 SER A OG  1 
ATOM   26   N N   . LYS A 1 167 ? 84.105  81.112  24.096 1.00 169.67 ? 166 LYS A N   1 
ATOM   27   C CA  . LYS A 1 167 ? 85.201  80.153  23.927 1.00 212.54 ? 166 LYS A CA  1 
ATOM   28   C C   . LYS A 1 167 ? 86.167  80.575  22.807 1.00 263.95 ? 166 LYS A C   1 
ATOM   29   O O   . LYS A 1 167 ? 87.393  80.508  22.971 1.00 215.60 ? 166 LYS A O   1 
ATOM   30   C CB  . LYS A 1 167 ? 84.621  78.759  23.655 1.00 177.99 ? 166 LYS A CB  1 
ATOM   31   C CG  . LYS A 1 167 ? 85.656  77.640  23.659 1.00 198.66 ? 166 LYS A CG  1 
ATOM   32   C CD  . LYS A 1 167 ? 85.095  76.273  23.342 1.00 243.08 ? 166 LYS A CD  1 
ATOM   33   C CE  . LYS A 1 167 ? 86.029  75.133  23.715 1.00 278.70 ? 166 LYS A CE  1 
ATOM   34   N NZ  . LYS A 1 167 ? 87.268  75.069  22.898 1.00 284.86 ? 166 LYS A NZ  1 
ATOM   35   N N   . GLU A 1 168 ? 85.586  81.027  21.685 1.00 295.20 ? 167 GLU A N   1 
ATOM   36   C CA  . GLU A 1 168 ? 86.306  81.410  20.477 1.00 320.19 ? 167 GLU A CA  1 
ATOM   37   C C   . GLU A 1 168 ? 87.176  82.658  20.682 1.00 323.61 ? 167 GLU A C   1 
ATOM   38   O O   . GLU A 1 168 ? 88.129  82.855  19.924 1.00 380.78 ? 167 GLU A O   1 
ATOM   39   C CB  . GLU A 1 168 ? 85.313  81.639  19.329 1.00 365.44 ? 167 GLU A CB  1 
ATOM   40   C CG  . GLU A 1 168 ? 84.446  80.429  18.981 1.00 426.58 ? 167 GLU A CG  1 
ATOM   41   C CD  . GLU A 1 168 ? 83.179  80.202  19.800 1.00 469.85 ? 167 GLU A CD  1 
ATOM   42   O OE1 . GLU A 1 168 ? 82.962  80.937  20.788 1.00 471.94 ? 167 GLU A OE1 1 
ATOM   43   O OE2 . GLU A 1 168 ? 82.412  79.283  19.449 1.00 516.50 ? 167 GLU A OE2 1 
ATOM   44   N N   . GLU A 1 169 ? 86.863  83.505  21.684 1.00 265.50 ? 168 GLU A N   1 
ATOM   45   C CA  . GLU A 1 169 ? 87.750  84.587  22.109 1.00 280.02 ? 168 GLU A CA  1 
ATOM   46   C C   . GLU A 1 169 ? 88.772  84.089  23.138 1.00 269.45 ? 168 GLU A C   1 
ATOM   47   O O   . GLU A 1 169 ? 89.977  84.266  22.949 1.00 294.97 ? 168 GLU A O   1 
ATOM   48   C CB  . GLU A 1 169 ? 86.949  85.761  22.669 1.00 276.50 ? 168 GLU A CB  1 
ATOM   49   C CG  . GLU A 1 169 ? 86.115  86.498  21.628 1.00 317.69 ? 168 GLU A CG  1 
ATOM   50   C CD  . GLU A 1 169 ? 84.726  85.935  21.375 1.00 325.39 ? 168 GLU A CD  1 
ATOM   51   O OE1 . GLU A 1 169 ? 83.895  85.981  22.308 1.00 362.48 ? 168 GLU A OE1 1 
ATOM   52   O OE2 . GLU A 1 169 ? 84.467  85.464  20.247 1.00 322.39 ? 168 GLU A OE2 1 
ATOM   53   N N   . LEU A 1 170 ? 88.306  83.462  24.226 1.00 259.21 ? 169 LEU A N   1 
ATOM   54   C CA  . LEU A 1 170 ? 89.164  83.130  25.363 1.00 313.66 ? 169 LEU A CA  1 
ATOM   55   C C   . LEU A 1 170 ? 90.346  82.218  25.015 1.00 341.08 ? 169 LEU A C   1 
ATOM   56   O O   . LEU A 1 170 ? 91.383  82.323  25.670 1.00 358.98 ? 169 LEU A O   1 
ATOM   57   C CB  . LEU A 1 170 ? 88.303  82.519  26.468 1.00 321.71 ? 169 LEU A CB  1 
ATOM   58   C CG  . LEU A 1 170 ? 87.622  83.558  27.342 1.00 316.88 ? 169 LEU A CG  1 
ATOM   59   C CD1 . LEU A 1 170 ? 86.405  82.975  28.020 1.00 368.84 ? 169 LEU A CD1 1 
ATOM   60   C CD2 . LEU A 1 170 ? 88.597  84.090  28.382 1.00 360.64 ? 169 LEU A CD2 1 
ATOM   61   N N   . LEU A 1 171 ? 90.227  81.355  23.995 1.00 351.09 ? 170 LEU A N   1 
ATOM   62   C CA  . LEU A 1 171 ? 91.323  80.466  23.608 1.00 395.96 ? 170 LEU A CA  1 
ATOM   63   C C   . LEU A 1 171 ? 92.607  81.204  23.157 1.00 424.27 ? 170 LEU A C   1 
ATOM   64   O O   . LEU A 1 171 ? 93.651  80.549  23.065 1.00 439.73 ? 170 LEU A O   1 
ATOM   65   C CB  . LEU A 1 171 ? 90.812  79.457  22.557 1.00 445.03 ? 170 LEU A CB  1 
ATOM   66   C CG  . LEU A 1 171 ? 90.314  79.968  21.199 1.00 494.07 ? 170 LEU A CG  1 
ATOM   67   C CD1 . LEU A 1 171 ? 91.451  80.254  20.221 1.00 527.75 ? 170 LEU A CD1 1 
ATOM   68   C CD2 . LEU A 1 171 ? 89.367  78.951  20.572 1.00 486.11 ? 170 LEU A CD2 1 
ATOM   69   N N   . LYS A 1 172 ? 92.571  82.532  22.878 1.00 431.63 ? 171 LYS A N   1 
ATOM   70   C CA  . LYS A 1 172 ? 93.774  83.324  22.576 1.00 427.88 ? 171 LYS A CA  1 
ATOM   71   C C   . LYS A 1 172 ? 94.078  84.449  23.587 1.00 398.37 ? 171 LYS A C   1 
ATOM   72   O O   . LYS A 1 172 ? 95.138  85.072  23.491 1.00 387.25 ? 171 LYS A O   1 
ATOM   73   C CB  . LYS A 1 172 ? 93.660  83.907  21.159 1.00 439.14 ? 171 LYS A CB  1 
ATOM   74   C CG  . LYS A 1 172 ? 92.765  85.134  20.998 1.00 430.33 ? 171 LYS A CG  1 
ATOM   75   C CD  . LYS A 1 172 ? 92.043  85.214  19.664 1.00 425.43 ? 171 LYS A CD  1 
ATOM   76   C CE  . LYS A 1 172 ? 90.913  84.210  19.555 1.00 415.99 ? 171 LYS A CE  1 
ATOM   77   N NZ  . LYS A 1 172 ? 90.030  84.466  18.392 1.00 393.61 ? 171 LYS A NZ  1 
ATOM   78   N N   . VAL A 1 173 ? 93.178  84.714  24.551 1.00 368.02 ? 172 VAL A N   1 
ATOM   79   C CA  . VAL A 1 173 ? 93.349  85.735  25.588 1.00 351.36 ? 172 VAL A CA  1 
ATOM   80   C C   . VAL A 1 173 ? 94.233  85.226  26.744 1.00 331.52 ? 172 VAL A C   1 
ATOM   81   O O   . VAL A 1 173 ? 94.774  86.031  27.511 1.00 328.19 ? 172 VAL A O   1 
ATOM   82   C CB  . VAL A 1 173 ? 91.961  86.232  26.061 1.00 326.69 ? 172 VAL A CB  1 
ATOM   83   C CG1 . VAL A 1 173 ? 92.021  87.182  27.258 1.00 298.24 ? 172 VAL A CG1 1 
ATOM   84   C CG2 . VAL A 1 173 ? 91.209  86.902  24.920 1.00 312.60 ? 172 VAL A CG2 1 
ATOM   85   N N   . ALA A 1 174 ? 94.401  83.898  26.871 1.00 305.74 ? 173 ALA A N   1 
ATOM   86   C CA  . ALA A 1 174 ? 95.266  83.256  27.858 1.00 306.60 ? 173 ALA A CA  1 
ATOM   87   C C   . ALA A 1 174 ? 96.772  83.403  27.544 1.00 350.35 ? 173 ALA A C   1 
ATOM   88   O O   . ALA A 1 174 ? 97.468  82.409  27.318 1.00 308.30 ? 173 ALA A O   1 
ATOM   89   C CB  . ALA A 1 174 ? 94.843  81.800  27.931 1.00 284.24 ? 173 ALA A CB  1 
ATOM   90   N N   . GLY A 1 175 ? 97.303  84.643  27.542 1.00 350.23 ? 174 GLY A N   1 
ATOM   91   C CA  . GLY A 1 175 ? 98.718  84.893  27.280 1.00 312.58 ? 174 GLY A CA  1 
ATOM   92   C C   . GLY A 1 175 ? 99.600  84.425  28.438 1.00 266.96 ? 174 GLY A C   1 
ATOM   93   O O   . GLY A 1 175 ? 99.408  84.877  29.557 1.00 219.74 ? 174 GLY A O   1 
ATOM   94   N N   . SER A 1 176 ? 100.570 83.536  28.162 1.00 296.65 ? 175 SER A N   1 
ATOM   95   C CA  . SER A 1 176 ? 101.255 82.745  29.188 1.00 330.87 ? 175 SER A CA  1 
ATOM   96   C C   . SER A 1 176 ? 101.914 83.588  30.300 1.00 334.52 ? 175 SER A C   1 
ATOM   97   O O   . SER A 1 176 ? 101.760 83.240  31.473 1.00 244.75 ? 175 SER A O   1 
ATOM   98   C CB  . SER A 1 176 ? 102.245 81.778  28.542 1.00 347.11 ? 175 SER A CB  1 
ATOM   99   O OG  . SER A 1 176 ? 102.869 80.952  29.517 1.00 350.01 ? 175 SER A OG  1 
ATOM   100  N N   . PRO A 1 177 ? 102.662 84.694  30.021 1.00 403.75 ? 176 PRO A N   1 
ATOM   101  C CA  . PRO A 1 177 ? 103.266 85.522  31.079 1.00 423.67 ? 176 PRO A CA  1 
ATOM   102  C C   . PRO A 1 177 ? 102.317 86.127  32.122 1.00 407.82 ? 176 PRO A C   1 
ATOM   103  O O   . PRO A 1 177 ? 102.778 86.458  33.215 1.00 423.04 ? 176 PRO A O   1 
ATOM   104  C CB  . PRO A 1 177 ? 103.960 86.663  30.303 1.00 431.87 ? 176 PRO A CB  1 
ATOM   105  C CG  . PRO A 1 177 ? 104.207 86.095  28.929 1.00 433.35 ? 176 PRO A CG  1 
ATOM   106  C CD  . PRO A 1 177 ? 103.000 85.215  28.685 1.00 434.79 ? 176 PRO A CD  1 
ATOM   107  N N   . GLY A 1 178 ? 101.017 86.265  31.792 1.00 348.70 ? 177 GLY A N   1 
ATOM   108  C CA  . GLY A 1 178 ? 100.001 86.789  32.703 1.00 303.64 ? 177 GLY A CA  1 
ATOM   109  C C   . GLY A 1 178 ? 99.141  85.696  33.344 1.00 260.77 ? 177 GLY A C   1 
ATOM   110  O O   . GLY A 1 178 ? 99.473  85.157  34.400 1.00 234.15 ? 177 GLY A O   1 
ATOM   111  N N   . TRP A 1 179 ? 98.022  85.362  32.689 1.00 245.61 ? 178 TRP A N   1 
ATOM   112  C CA  . TRP A 1 179 ? 96.960  84.566  33.294 1.00 205.35 ? 178 TRP A CA  1 
ATOM   113  C C   . TRP A 1 179 ? 97.390  83.120  33.541 1.00 186.91 ? 178 TRP A C   1 
ATOM   114  O O   . TRP A 1 179 ? 97.035  82.594  34.588 1.00 304.80 ? 178 TRP A O   1 
ATOM   115  C CB  . TRP A 1 179 ? 95.663  84.633  32.473 1.00 198.91 ? 178 TRP A CB  1 
ATOM   116  C CG  . TRP A 1 179 ? 95.184  86.051  32.302 1.00 246.58 ? 178 TRP A CG  1 
ATOM   117  C CD1 . TRP A 1 179 ? 95.290  86.775  31.151 1.00 337.90 ? 178 TRP A CD1 1 
ATOM   118  C CD2 . TRP A 1 179 ? 94.558  86.925  33.280 1.00 248.05 ? 178 TRP A CD2 1 
ATOM   119  N NE1 . TRP A 1 179 ? 94.771  88.030  31.341 1.00 347.83 ? 178 TRP A NE1 1 
ATOM   120  C CE2 . TRP A 1 179 ? 94.314  88.159  32.633 1.00 293.03 ? 178 TRP A CE2 1 
ATOM   121  C CE3 . TRP A 1 179 ? 94.179  86.794  34.625 1.00 304.55 ? 178 TRP A CE3 1 
ATOM   122  C CZ2 . TRP A 1 179 ? 93.707  89.242  33.291 1.00 280.71 ? 178 TRP A CZ2 1 
ATOM   123  C CZ3 . TRP A 1 179 ? 93.583  87.861  35.273 1.00 333.46 ? 178 TRP A CZ3 1 
ATOM   124  C CH2 . TRP A 1 179 ? 93.351  89.071  34.613 1.00 284.23 ? 178 TRP A CH2 1 
ATOM   125  N N   . VAL A 1 180 ? 98.146  82.469  32.649 1.00 122.49 ? 179 VAL A N   1 
ATOM   126  C CA  . VAL A 1 180 ? 98.501  81.059  32.850 1.00 187.32 ? 179 VAL A CA  1 
ATOM   127  C C   . VAL A 1 180 ? 99.415  80.892  34.074 1.00 204.57 ? 179 VAL A C   1 
ATOM   128  O O   . VAL A 1 180 ? 99.190  79.984  34.882 1.00 256.56 ? 179 VAL A O   1 
ATOM   129  C CB  . VAL A 1 180 ? 99.136  80.416  31.602 1.00 287.26 ? 179 VAL A CB  1 
ATOM   130  C CG1 . VAL A 1 180 ? 99.503  78.945  31.815 1.00 292.30 ? 179 VAL A CG1 1 
ATOM   131  C CG2 . VAL A 1 180 ? 98.218  80.547  30.396 1.00 339.71 ? 179 VAL A CG2 1 
ATOM   132  N N   . ARG A 1 181 ? 100.421 81.765  34.234 1.00 214.70 ? 180 ARG A N   1 
ATOM   133  C CA  . ARG A 1 181 ? 101.270 81.755  35.421 1.00 258.97 ? 180 ARG A CA  1 
ATOM   134  C C   . ARG A 1 181 ? 100.464 82.104  36.685 1.00 239.54 ? 180 ARG A C   1 
ATOM   135  O O   . ARG A 1 181 ? 100.681 81.508  37.745 1.00 241.35 ? 180 ARG A O   1 
ATOM   136  C CB  . ARG A 1 181 ? 102.465 82.697  35.208 1.00 318.78 ? 180 ARG A CB  1 
ATOM   137  C CG  . ARG A 1 181 ? 103.654 82.453  36.127 1.00 350.81 ? 180 ARG A CG  1 
ATOM   138  C CD  . ARG A 1 181 ? 104.402 81.162  35.831 1.00 379.98 ? 180 ARG A CD  1 
ATOM   139  N NE  . ARG A 1 181 ? 105.572 80.973  36.686 1.00 389.66 ? 180 ARG A NE  1 
ATOM   140  C CZ  . ARG A 1 181 ? 106.370 79.900  36.686 1.00 378.39 ? 180 ARG A CZ  1 
ATOM   141  N NH1 . ARG A 1 181 ? 107.391 79.839  37.527 1.00 320.82 ? 180 ARG A NH1 1 
ATOM   142  N NH2 . ARG A 1 181 ? 106.158 78.890  35.855 1.00 381.94 ? 180 ARG A NH2 1 
ATOM   143  N N   . THR A 1 182 ? 99.523  83.062  36.585 1.00 220.25 ? 181 THR A N   1 
ATOM   144  C CA  . THR A 1 182 ? 98.632  83.446  37.683 1.00 221.98 ? 181 THR A CA  1 
ATOM   145  C C   . THR A 1 182 ? 97.774  82.266  38.157 1.00 168.85 ? 181 THR A C   1 
ATOM   146  O O   . THR A 1 182 ? 97.696  82.008  39.354 1.00 167.64 ? 181 THR A O   1 
ATOM   147  C CB  . THR A 1 182 ? 97.744  84.641  37.289 1.00 247.70 ? 181 THR A CB  1 
ATOM   148  O OG1 . THR A 1 182 ? 98.584  85.743  36.942 1.00 267.03 ? 181 THR A OG1 1 
ATOM   149  C CG2 . THR A 1 182 ? 96.798  85.107  38.374 1.00 240.06 ? 181 THR A CG2 1 
ATOM   150  N N   . ARG A 1 183 ? 97.128  81.551  37.228 1.00 183.44 ? 182 ARG A N   1 
ATOM   151  C CA  . ARG A 1 183 ? 96.281  80.399  37.534 1.00 164.59 ? 182 ARG A CA  1 
ATOM   152  C C   . ARG A 1 183 ? 97.080  79.208  38.068 1.00 165.85 ? 182 ARG A C   1 
ATOM   153  O O   . ARG A 1 183 ? 96.555  78.483  38.911 1.00 242.36 ? 182 ARG A O   1 
ATOM   154  C CB  . ARG A 1 183 ? 95.431  80.038  36.312 1.00 154.17 ? 182 ARG A CB  1 
ATOM   155  C CG  . ARG A 1 183 ? 94.264  81.013  36.152 1.00 177.86 ? 182 ARG A CG  1 
ATOM   156  C CD  . ARG A 1 183 ? 93.299  80.598  35.054 1.00 206.75 ? 182 ARG A CD  1 
ATOM   157  N NE  . ARG A 1 183 ? 93.566  81.198  33.757 1.00 186.58 ? 182 ARG A NE  1 
ATOM   158  C CZ  . ARG A 1 183 ? 94.129  80.590  32.713 1.00 189.44 ? 182 ARG A CZ  1 
ATOM   159  N NH1 . ARG A 1 183 ? 94.090  81.191  31.540 1.00 212.09 ? 182 ARG A NH1 1 
ATOM   160  N NH2 . ARG A 1 183 ? 94.715  79.402  32.811 1.00 179.21 ? 182 ARG A NH2 1 
ATOM   161  N N   . TRP A 1 184 ? 98.329  79.007  37.641 1.00 175.06 ? 183 TRP A N   1 
ATOM   162  C CA  . TRP A 1 184 ? 99.224  78.083  38.330 1.00 189.70 ? 183 TRP A CA  1 
ATOM   163  C C   . TRP A 1 184 ? 99.461  78.498  39.790 1.00 174.52 ? 183 TRP A C   1 
ATOM   164  O O   . TRP A 1 184 ? 99.342  77.656  40.693 1.00 208.66 ? 183 TRP A O   1 
ATOM   165  C CB  . TRP A 1 184 ? 100.556 77.965  37.587 1.00 238.65 ? 183 TRP A CB  1 
ATOM   166  C CG  . TRP A 1 184 ? 101.546 77.109  38.331 1.00 264.31 ? 183 TRP A CG  1 
ATOM   167  C CD1 . TRP A 1 184 ? 102.614 77.540  39.068 1.00 252.03 ? 183 TRP A CD1 1 
ATOM   168  C CD2 . TRP A 1 184 ? 101.554 75.660  38.406 1.00 277.60 ? 183 TRP A CD2 1 
ATOM   169  N NE1 . TRP A 1 184 ? 103.280 76.465  39.595 1.00 272.17 ? 183 TRP A NE1 1 
ATOM   170  C CE2 . TRP A 1 184 ? 102.666 75.294  39.207 1.00 297.09 ? 183 TRP A CE2 1 
ATOM   171  C CE3 . TRP A 1 184 ? 100.750 74.631  37.873 1.00 250.32 ? 183 TRP A CE3 1 
ATOM   172  C CZ2 . TRP A 1 184 ? 102.976 73.950  39.485 1.00 301.75 ? 183 TRP A CZ2 1 
ATOM   173  C CZ3 . TRP A 1 184 ? 101.058 73.309  38.143 1.00 279.79 ? 183 TRP A CZ3 1 
ATOM   174  C CH2 . TRP A 1 184 ? 102.159 72.975  38.941 1.00 296.60 ? 183 TRP A CH2 1 
ATOM   175  N N   . ALA A 1 185 ? 99.763  79.785  40.030 1.00 163.51 ? 184 ALA A N   1 
ATOM   176  C CA  . ALA A 1 185 ? 100.002 80.293  41.380 1.00 259.10 ? 184 ALA A CA  1 
ATOM   177  C C   . ALA A 1 185 ? 98.777  80.126  42.305 1.00 225.05 ? 184 ALA A C   1 
ATOM   178  O O   . ALA A 1 185 ? 98.916  79.666  43.437 1.00 202.44 ? 184 ALA A O   1 
ATOM   179  C CB  . ALA A 1 185 ? 100.476 81.734  41.312 1.00 296.14 ? 184 ALA A CB  1 
ATOM   180  N N   . LEU A 1 186 ? 97.567  80.474  41.860 1.00 171.00 ? 185 LEU A N   1 
ATOM   181  C CA  . LEU A 1 186 ? 96.388  80.294  42.689 1.00 120.58 ? 185 LEU A CA  1 
ATOM   182  C C   . LEU A 1 186 ? 96.100  78.818  42.947 1.00 133.94 ? 185 LEU A C   1 
ATOM   183  O O   . LEU A 1 186 ? 95.680  78.487  44.066 1.00 256.14 ? 185 LEU A O   1 
ATOM   184  C CB  . LEU A 1 186 ? 95.162  80.933  42.019 1.00 146.70 ? 185 LEU A CB  1 
ATOM   185  C CG  . LEU A 1 186 ? 95.114  82.456  41.975 1.00 194.09 ? 185 LEU A CG  1 
ATOM   186  C CD1 . LEU A 1 186 ? 93.724  82.874  41.541 1.00 230.50 ? 185 LEU A CD1 1 
ATOM   187  C CD2 . LEU A 1 186 ? 95.436  83.136  43.305 1.00 196.85 ? 185 LEU A CD2 1 
ATOM   188  N N   . LEU A 1 187 ? 96.268  77.929  41.963 1.00 123.13 ? 186 LEU A N   1 
ATOM   189  C CA  . LEU A 1 187 ? 96.037  76.509  42.181 1.00 145.91 ? 186 LEU A CA  1 
ATOM   190  C C   . LEU A 1 187 ? 97.044  75.955  43.213 1.00 172.77 ? 186 LEU A C   1 
ATOM   191  O O   . LEU A 1 187 ? 96.641  75.169  44.091 1.00 246.56 ? 186 LEU A O   1 
ATOM   192  C CB  . LEU A 1 187 ? 96.096  75.800  40.826 1.00 178.34 ? 186 LEU A CB  1 
ATOM   193  C CG  . LEU A 1 187 ? 95.654  74.331  40.735 1.00 203.28 ? 186 LEU A CG  1 
ATOM   194  C CD1 . LEU A 1 187 ? 96.690  73.315  41.302 1.00 187.14 ? 186 LEU A CD1 1 
ATOM   195  C CD2 . LEU A 1 187 ? 94.287  74.184  41.373 1.00 162.80 ? 186 LEU A CD2 1 
ATOM   196  N N   . LEU A 1 188 ? 98.324  76.365  43.160 1.00 139.50 ? 187 LEU A N   1 
ATOM   197  C CA  . LEU A 1 188 ? 99.265  76.017  44.216 1.00 199.02 ? 187 LEU A CA  1 
ATOM   198  C C   . LEU A 1 188 ? 98.873  76.644  45.569 1.00 197.92 ? 187 LEU A C   1 
ATOM   199  O O   . LEU A 1 188 ? 98.972  75.980  46.601 1.00 231.37 ? 187 LEU A O   1 
ATOM   200  C CB  . LEU A 1 188 ? 100.682 76.434  43.809 1.00 264.17 ? 187 LEU A CB  1 
ATOM   201  C CG  . LEU A 1 188 ? 101.767 76.158  44.854 1.00 308.12 ? 187 LEU A CG  1 
ATOM   202  C CD1 . LEU A 1 188 ? 101.908 74.661  45.123 1.00 298.04 ? 187 LEU A CD1 1 
ATOM   203  C CD2 . LEU A 1 188 ? 103.093 76.756  44.420 1.00 370.38 ? 187 LEU A CD2 1 
ATOM   204  N N   . LEU A 1 189 ? 98.425  77.908  45.589 1.00 159.20 ? 188 LEU A N   1 
ATOM   205  C CA  . LEU A 1 189 ? 98.023  78.572  46.826 1.00 199.74 ? 188 LEU A CA  1 
ATOM   206  C C   . LEU A 1 189 ? 96.849  77.848  47.504 1.00 175.07 ? 188 LEU A C   1 
ATOM   207  O O   . LEU A 1 189 ? 96.821  77.736  48.724 1.00 194.55 ? 188 LEU A O   1 
ATOM   208  C CB  . LEU A 1 189 ? 97.689  80.044  46.541 1.00 223.72 ? 188 LEU A CB  1 
ATOM   209  C CG  . LEU A 1 189 ? 97.215  80.881  47.731 1.00 303.43 ? 188 LEU A CG  1 
ATOM   210  C CD1 . LEU A 1 189 ? 98.269  80.944  48.829 1.00 352.91 ? 188 LEU A CD1 1 
ATOM   211  C CD2 . LEU A 1 189 ? 96.849  82.284  47.285 1.00 312.70 ? 188 LEU A CD2 1 
ATOM   212  N N   . PHE A 1 190 ? 95.877  77.352  46.741 1.00 156.54 ? 189 PHE A N   1 
ATOM   213  C CA  . PHE A 1 190 ? 94.806  76.542  47.293 1.00 116.70 ? 189 PHE A CA  1 
ATOM   214  C C   . PHE A 1 190 ? 95.354  75.296  47.971 1.00 105.64 ? 189 PHE A C   1 
ATOM   215  O O   . PHE A 1 190 ? 95.064  75.116  49.172 1.00 213.68 ? 189 PHE A O   1 
ATOM   216  C CB  . PHE A 1 190 ? 93.824  76.134  46.213 1.00 144.35 ? 189 PHE A CB  1 
ATOM   217  C CG  . PHE A 1 190 ? 92.743  75.161  46.633 1.00 159.83 ? 189 PHE A CG  1 
ATOM   218  C CD1 . PHE A 1 190 ? 92.977  73.770  46.552 1.00 90.84  ? 189 PHE A CD1 1 
ATOM   219  C CD2 . PHE A 1 190 ? 91.503  75.635  47.096 1.00 158.02 ? 189 PHE A CD2 1 
ATOM   220  C CE1 . PHE A 1 190 ? 91.982  72.872  46.914 1.00 132.07 ? 189 PHE A CE1 1 
ATOM   221  C CE2 . PHE A 1 190 ? 90.528  74.721  47.469 1.00 190.01 ? 189 PHE A CE2 1 
ATOM   222  C CZ  . PHE A 1 190 ? 90.765  73.351  47.371 1.00 224.65 ? 189 PHE A CZ  1 
ATOM   223  N N   . TRP A 1 191 ? 96.115  74.442  47.277 1.00 82.05  ? 190 TRP A N   1 
ATOM   224  C CA  . TRP A 1 191 ? 96.615  73.247  47.957 1.00 160.40 ? 190 TRP A CA  1 
ATOM   225  C C   . TRP A 1 191 ? 97.603  73.517  49.109 1.00 205.25 ? 190 TRP A C   1 
ATOM   226  O O   . TRP A 1 191 ? 97.591  72.765  50.090 1.00 215.53 ? 190 TRP A O   1 
ATOM   227  C CB  . TRP A 1 191 ? 97.171  72.260  46.933 1.00 182.95 ? 190 TRP A CB  1 
ATOM   228  C CG  . TRP A 1 191 ? 96.040  71.557  46.244 1.00 146.94 ? 190 TRP A CG  1 
ATOM   229  C CD1 . TRP A 1 191 ? 95.551  71.879  45.024 1.00 161.54 ? 190 TRP A CD1 1 
ATOM   230  C CD2 . TRP A 1 191 ? 95.288  70.415  46.718 1.00 161.12 ? 190 TRP A CD2 1 
ATOM   231  N NE1 . TRP A 1 191 ? 94.535  71.020  44.707 1.00 210.74 ? 190 TRP A NE1 1 
ATOM   232  C CE2 . TRP A 1 191 ? 94.346  70.111  45.720 1.00 205.17 ? 190 TRP A CE2 1 
ATOM   233  C CE3 . TRP A 1 191 ? 95.313  69.619  47.876 1.00 244.94 ? 190 TRP A CE3 1 
ATOM   234  C CZ2 . TRP A 1 191 ? 93.440  69.050  45.844 1.00 281.86 ? 190 TRP A CZ2 1 
ATOM   235  C CZ3 . TRP A 1 191 ? 94.425  68.569  48.002 1.00 296.36 ? 190 TRP A CZ3 1 
ATOM   236  C CH2 . TRP A 1 191 ? 93.501  68.291  46.994 1.00 318.08 ? 190 TRP A CH2 1 
ATOM   237  N N   . LEU A 1 192 ? 98.436  74.559  49.012 1.00 201.59 ? 191 LEU A N   1 
ATOM   238  C CA  . LEU A 1 192 ? 99.247  75.005  50.136 1.00 228.57 ? 191 LEU A CA  1 
ATOM   239  C C   . LEU A 1 192 ? 98.364  75.416  51.327 1.00 187.44 ? 191 LEU A C   1 
ATOM   240  O O   . LEU A 1 192 ? 98.642  75.024  52.454 1.00 207.50 ? 191 LEU A O   1 
ATOM   241  C CB  . LEU A 1 192 ? 100.154 76.146  49.653 1.00 296.67 ? 191 LEU A CB  1 
ATOM   242  C CG  . LEU A 1 192 ? 101.117 76.727  50.692 1.00 389.02 ? 191 LEU A CG  1 
ATOM   243  C CD1 . LEU A 1 192 ? 102.188 75.716  51.081 1.00 414.95 ? 191 LEU A CD1 1 
ATOM   244  C CD2 . LEU A 1 192 ? 101.758 78.003  50.174 1.00 445.18 ? 191 LEU A CD2 1 
ATOM   245  N N   . GLY A 1 193 ? 97.302  76.201  51.090 1.00 158.03 ? 192 GLY A N   1 
ATOM   246  C CA  . GLY A 1 193 ? 96.356  76.639  52.118 1.00 197.46 ? 192 GLY A CA  1 
ATOM   247  C C   . GLY A 1 193 ? 95.503  75.515  52.733 1.00 154.76 ? 192 GLY A C   1 
ATOM   248  O O   . GLY A 1 193 ? 95.242  75.498  53.938 1.00 155.73 ? 192 GLY A O   1 
ATOM   249  N N   . TRP A 1 194 ? 95.072  74.555  51.914 1.00 127.11 ? 193 TRP A N   1 
ATOM   250  C CA  . TRP A 1 194 ? 94.363  73.383  52.408 1.00 104.05 ? 193 TRP A CA  1 
ATOM   251  C C   . TRP A 1 194 ? 95.284  72.462  53.193 1.00 110.76 ? 193 TRP A C   1 
ATOM   252  O O   . TRP A 1 194 ? 94.847  71.990  54.252 1.00 219.55 ? 193 TRP A O   1 
ATOM   253  C CB  . TRP A 1 194 ? 93.785  72.652  51.236 1.00 137.56 ? 193 TRP A CB  1 
ATOM   254  C CG  . TRP A 1 194 ? 92.937  71.437  51.433 1.00 122.42 ? 193 TRP A CG  1 
ATOM   255  C CD1 . TRP A 1 194 ? 91.564  71.419  51.286 1.00 103.26 ? 193 TRP A CD1 1 
ATOM   256  C CD2 . TRP A 1 194 ? 93.372  70.083  51.681 1.00 86.47  ? 193 TRP A CD2 1 
ATOM   257  N NE1 . TRP A 1 194 ? 91.097  70.141  51.425 1.00 101.83 ? 193 TRP A NE1 1 
ATOM   258  C CE2 . TRP A 1 194 ? 92.169  69.291  51.671 1.00 137.75 ? 193 TRP A CE2 1 
ATOM   259  C CE3 . TRP A 1 194 ? 94.594  69.451  51.889 1.00 62.10  ? 193 TRP A CE3 1 
ATOM   260  C CZ2 . TRP A 1 194 ? 92.193  67.896  51.890 1.00 113.60 ? 193 TRP A CZ2 1 
ATOM   261  C CZ3 . TRP A 1 194 ? 94.608  68.084  52.104 1.00 148.42 ? 193 TRP A CZ3 1 
ATOM   262  C CH2 . TRP A 1 194 ? 93.425  67.311  52.085 1.00 136.44 ? 193 TRP A CH2 1 
ATOM   263  N N   . LEU A 1 195 ? 96.542  72.244  52.782 1.00 116.00 ? 194 LEU A N   1 
ATOM   264  C CA  . LEU A 1 195 ? 97.489  71.546  53.657 1.00 150.93 ? 194 LEU A CA  1 
ATOM   265  C C   . LEU A 1 195 ? 97.808  72.344  54.927 1.00 164.65 ? 194 LEU A C   1 
ATOM   266  O O   . LEU A 1 195 ? 98.029  71.747  55.980 1.00 136.60 ? 194 LEU A O   1 
ATOM   267  C CB  . LEU A 1 195 ? 98.755  71.204  52.877 1.00 148.78 ? 194 LEU A CB  1 
ATOM   268  C CG  . LEU A 1 195 ? 98.568  70.059  51.886 1.00 207.54 ? 194 LEU A CG  1 
ATOM   269  C CD1 . LEU A 1 195 ? 99.778  69.960  50.967 1.00 329.07 ? 194 LEU A CD1 1 
ATOM   270  C CD2 . LEU A 1 195 ? 98.328  68.716  52.584 1.00 153.93 ? 194 LEU A CD2 1 
ATOM   271  N N   . GLY A 1 196 ? 97.823  73.677  54.862 1.00 146.69 ? 195 GLY A N   1 
ATOM   272  C CA  . GLY A 1 196 ? 97.862  74.512  56.057 1.00 199.75 ? 195 GLY A CA  1 
ATOM   273  C C   . GLY A 1 196 ? 96.705  74.266  57.030 1.00 155.44 ? 195 GLY A C   1 
ATOM   274  O O   . GLY A 1 196 ? 96.940  74.152  58.227 1.00 133.95 ? 195 GLY A O   1 
ATOM   275  N N   . MET A 1 197 ? 95.470  74.175  56.522 1.00 148.90 ? 196 MET A N   1 
ATOM   276  C CA  . MET A 1 197 ? 94.280  73.892  57.319 1.00 117.53 ? 196 MET A CA  1 
ATOM   277  C C   . MET A 1 197 ? 94.326  72.452  57.834 1.00 78.94  ? 196 MET A C   1 
ATOM   278  O O   . MET A 1 197 ? 93.907  72.221  58.970 1.00 168.53 ? 196 MET A O   1 
ATOM   279  C CB  . MET A 1 197 ? 93.010  74.190  56.505 1.00 124.07 ? 196 MET A CB  1 
ATOM   280  C CG  . MET A 1 197 ? 91.678  73.683  57.101 1.00 117.92 ? 196 MET A CG  1 
ATOM   281  S SD  . MET A 1 197 ? 90.099  74.009  56.097 1.00 178.54 ? 196 MET A SD  1 
ATOM   282  C CE  . MET A 1 197 ? 89.877  75.781  56.373 1.00 123.02 ? 196 MET A CE  1 
ATOM   283  N N   . LEU A 1 198 ? 94.851  71.486  57.077 1.00 83.16  ? 197 LEU A N   1 
ATOM   284  C CA  . LEU A 1 198 ? 95.031  70.117  57.547 1.00 100.86 ? 197 LEU A CA  1 
ATOM   285  C C   . LEU A 1 198 ? 96.057  70.116  58.680 1.00 114.19 ? 197 LEU A C   1 
ATOM   286  O O   . LEU A 1 198 ? 95.799  69.521  59.736 1.00 135.30 ? 197 LEU A O   1 
ATOM   287  C CB  . LEU A 1 198 ? 95.433  69.239  56.367 1.00 131.89 ? 197 LEU A CB  1 
ATOM   288  C CG  . LEU A 1 198 ? 95.548  67.713  56.593 1.00 121.49 ? 197 LEU A CG  1 
ATOM   289  C CD1 . LEU A 1 198 ? 96.774  67.314  57.398 1.00 123.24 ? 197 LEU A CD1 1 
ATOM   290  C CD2 . LEU A 1 198 ? 94.316  67.095  57.205 1.00 111.67 ? 197 LEU A CD2 1 
ATOM   291  N N   . ALA A 1 199 ? 97.181  70.816  58.516 1.00 90.90  ? 198 ALA A N   1 
ATOM   292  C CA  . ALA A 1 199 ? 98.145  70.906  59.598 1.00 155.45 ? 198 ALA A CA  1 
ATOM   293  C C   . ALA A 1 199 ? 97.527  71.585  60.832 1.00 158.13 ? 198 ALA A C   1 
ATOM   294  O O   . ALA A 1 199 ? 97.758  71.136  61.960 1.00 179.00 ? 198 ALA A O   1 
ATOM   295  C CB  . ALA A 1 199 ? 99.379  71.618  59.093 1.00 229.41 ? 198 ALA A CB  1 
ATOM   296  N N   . GLY A 1 200 ? 96.757  72.670  60.652 1.00 163.72 ? 199 GLY A N   1 
ATOM   297  C CA  . GLY A 1 200 ? 96.033  73.333  61.738 1.00 191.61 ? 199 GLY A CA  1 
ATOM   298  C C   . GLY A 1 200 ? 95.104  72.397  62.519 1.00 119.48 ? 199 GLY A C   1 
ATOM   299  O O   . GLY A 1 200 ? 95.135  72.350  63.725 1.00 124.40 ? 199 GLY A O   1 
ATOM   300  N N   . ALA A 1 201 ? 94.281  71.632  61.823 1.00 130.77 ? 200 ALA A N   1 
ATOM   301  C CA  . ALA A 1 201 ? 93.422  70.645  62.446 1.00 157.11 ? 200 ALA A CA  1 
ATOM   302  C C   . ALA A 1 201 ? 94.257  69.594  63.182 1.00 162.47 ? 200 ALA A C   1 
ATOM   303  O O   . ALA A 1 201 ? 93.920  69.275  64.325 1.00 217.76 ? 200 ALA A O   1 
ATOM   304  C CB  . ALA A 1 201 ? 92.497  70.044  61.406 1.00 158.28 ? 200 ALA A CB  1 
ATOM   305  N N   . VAL A 1 202 ? 95.337  69.058  62.583 1.00 107.49 ? 201 VAL A N   1 
ATOM   306  C CA  . VAL A 1 202 ? 96.163  68.069  63.268 1.00 133.28 ? 201 VAL A CA  1 
ATOM   307  C C   . VAL A 1 202 ? 96.836  68.655  64.512 1.00 149.55 ? 201 VAL A C   1 
ATOM   308  O O   . VAL A 1 202 ? 96.902  67.940  65.522 1.00 168.49 ? 201 VAL A O   1 
ATOM   309  C CB  . VAL A 1 202 ? 97.164  67.403  62.320 1.00 161.91 ? 201 VAL A CB  1 
ATOM   310  C CG1 . VAL A 1 202 ? 98.251  66.596  63.024 1.00 179.73 ? 201 VAL A CG1 1 
ATOM   311  C CG2 . VAL A 1 202 ? 96.422  66.504  61.363 1.00 202.47 ? 201 VAL A CG2 1 
ATOM   312  N N   . VAL A 1 203 ? 97.293  69.917  64.486 1.00 136.04 ? 202 VAL A N   1 
ATOM   313  C CA  . VAL A 1 203 ? 97.794  70.581  65.692 1.00 151.26 ? 202 VAL A CA  1 
ATOM   314  C C   . VAL A 1 203 ? 96.732  70.601  66.797 1.00 152.20 ? 202 VAL A C   1 
ATOM   315  O O   . VAL A 1 203 ? 97.056  70.204  67.912 1.00 142.78 ? 202 VAL A O   1 
ATOM   316  C CB  . VAL A 1 203 ? 98.335  71.996  65.381 1.00 171.19 ? 202 VAL A CB  1 
ATOM   317  C CG1 . VAL A 1 203 ? 98.354  72.994  66.553 1.00 170.35 ? 202 VAL A CG1 1 
ATOM   318  C CG2 . VAL A 1 203 ? 99.715  71.857  64.752 1.00 240.48 ? 202 VAL A CG2 1 
ATOM   319  N N   . ILE A 1 204 ? 95.495  71.041  66.511 1.00 128.92 ? 203 ILE A N   1 
ATOM   320  C CA  . ILE A 1 204 ? 94.447  71.134  67.520 1.00 121.05 ? 203 ILE A CA  1 
ATOM   321  C C   . ILE A 1 204 ? 94.185  69.751  68.126 1.00 108.31 ? 203 ILE A C   1 
ATOM   322  O O   . ILE A 1 204 ? 94.100  69.626  69.345 1.00 144.20 ? 203 ILE A O   1 
ATOM   323  C CB  . ILE A 1 204 ? 93.165  71.790  66.954 1.00 118.47 ? 203 ILE A CB  1 
ATOM   324  C CG1 . ILE A 1 204 ? 93.406  73.245  66.584 1.00 153.83 ? 203 ILE A CG1 1 
ATOM   325  C CG2 . ILE A 1 204 ? 92.014  71.743  67.935 1.00 166.13 ? 203 ILE A CG2 1 
ATOM   326  C CD1 . ILE A 1 204 ? 92.270  73.865  65.817 1.00 157.12 ? 203 ILE A CD1 1 
ATOM   327  N N   . ILE A 1 205 ? 94.058  68.713  67.302 1.00 82.28  ? 204 ILE A N   1 
ATOM   328  C CA  . ILE A 1 205 ? 93.821  67.364  67.793 1.00 84.19  ? 204 ILE A CA  1 
ATOM   329  C C   . ILE A 1 205 ? 95.015  66.824  68.609 1.00 137.24 ? 204 ILE A C   1 
ATOM   330  O O   . ILE A 1 205 ? 94.812  66.012  69.523 1.00 208.92 ? 204 ILE A O   1 
ATOM   331  C CB  . ILE A 1 205 ? 93.511  66.455  66.588 1.00 131.97 ? 204 ILE A CB  1 
ATOM   332  C CG1 . ILE A 1 205 ? 92.249  66.904  65.806 1.00 123.48 ? 204 ILE A CG1 1 
ATOM   333  C CG2 . ILE A 1 205 ? 93.487  64.958  66.960 1.00 103.87 ? 204 ILE A CG2 1 
ATOM   334  C CD1 . ILE A 1 205 ? 90.956  66.742  66.454 1.00 144.30 ? 204 ILE A CD1 1 
ATOM   335  N N   . VAL A 1 206 ? 96.263  67.246  68.330 1.00 136.41 ? 205 VAL A N   1 
ATOM   336  C CA  . VAL A 1 206 ? 97.422  66.842  69.134 1.00 171.50 ? 205 VAL A CA  1 
ATOM   337  C C   . VAL A 1 206 ? 97.513  67.593  70.473 1.00 177.41 ? 205 VAL A C   1 
ATOM   338  O O   . VAL A 1 206 ? 97.818  66.947  71.484 1.00 191.68 ? 205 VAL A O   1 
ATOM   339  C CB  . VAL A 1 206 ? 98.725  66.945  68.321 1.00 241.88 ? 205 VAL A CB  1 
ATOM   340  C CG1 . VAL A 1 206 ? 100.006 66.945  69.157 1.00 292.17 ? 205 VAL A CG1 1 
ATOM   341  C CG2 . VAL A 1 206 ? 98.774  65.811  67.309 1.00 284.70 ? 205 VAL A CG2 1 
ATOM   342  N N   . ARG A 1 207 ? 97.259  68.921  70.518 1.00 125.52 ? 206 ARG A N   1 
ATOM   343  C CA  . ARG A 1 207 ? 97.413  69.670  71.768 1.00 191.36 ? 206 ARG A CA  1 
ATOM   344  C C   . ARG A 1 207 ? 96.137  69.797  72.625 1.00 204.94 ? 206 ARG A C   1 
ATOM   345  O O   . ARG A 1 207 ? 96.251  70.203  73.788 1.00 248.60 ? 206 ARG A O   1 
ATOM   346  C CB  . ARG A 1 207 ? 98.054  71.036  71.498 1.00 216.98 ? 206 ARG A CB  1 
ATOM   347  C CG  . ARG A 1 207 ? 97.189  72.112  70.849 1.00 245.36 ? 206 ARG A CG  1 
ATOM   348  C CD  . ARG A 1 207 ? 97.919  73.453  70.861 1.00 304.38 ? 206 ARG A CD  1 
ATOM   349  N NE  . ARG A 1 207 ? 99.224  73.412  70.193 1.00 333.73 ? 206 ARG A NE  1 
ATOM   350  C CZ  . ARG A 1 207 ? 99.938  74.466  69.809 1.00 329.23 ? 206 ARG A CZ  1 
ATOM   351  N NH1 . ARG A 1 207 ? 101.104 74.285  69.209 1.00 292.39 ? 206 ARG A NH1 1 
ATOM   352  N NH2 . ARG A 1 207 ? 99.507  75.698  70.034 1.00 310.25 ? 206 ARG A NH2 1 
ATOM   353  N N   . ALA A 1 208 ? 94.944  69.465  72.110 1.00 200.66 ? 207 ALA A N   1 
ATOM   354  C CA  . ALA A 1 208 ? 93.751  69.370  72.944 1.00 222.26 ? 207 ALA A CA  1 
ATOM   355  C C   . ALA A 1 208 ? 93.906  68.281  74.022 1.00 205.75 ? 207 ALA A C   1 
ATOM   356  O O   . ALA A 1 208 ? 94.506  67.234  73.783 1.00 172.72 ? 207 ALA A O   1 
ATOM   357  C CB  . ALA A 1 208 ? 92.538  69.128  72.067 1.00 239.14 ? 207 ALA A CB  1 
ATOM   358  N N   . PRO A 1 209 ? 93.367  68.483  75.250 1.00 192.44 ? 208 PRO A N   1 
ATOM   359  C CA  . PRO A 1 209 ? 93.532  67.519  76.343 1.00 184.83 ? 208 PRO A CA  1 
ATOM   360  C C   . PRO A 1 209 ? 92.742  66.227  76.136 1.00 160.80 ? 208 PRO A C   1 
ATOM   361  O O   . PRO A 1 209 ? 91.545  66.286  75.863 1.00 131.66 ? 208 PRO A O   1 
ATOM   362  C CB  . PRO A 1 209 ? 92.974  68.260  77.564 1.00 239.47 ? 208 PRO A CB  1 
ATOM   363  C CG  . PRO A 1 209 ? 91.995  69.278  76.992 1.00 249.62 ? 208 PRO A CG  1 
ATOM   364  C CD  . PRO A 1 209 ? 92.559  69.648  75.639 1.00 210.74 ? 208 PRO A CD  1 
ATOM   365  N N   . ARG A 1 210 ? 93.426  65.075  76.249 1.00 152.57 ? 209 ARG A N   1 
ATOM   366  C CA  . ARG A 1 210 ? 92.813  63.764  76.038 1.00 156.28 ? 209 ARG A CA  1 
ATOM   367  C C   . ARG A 1 210 ? 91.925  63.390  77.211 1.00 149.42 ? 209 ARG A C   1 
ATOM   368  O O   . ARG A 1 210 ? 92.233  63.777  78.342 1.00 207.63 ? 209 ARG A O   1 
ATOM   369  C CB  . ARG A 1 210 ? 93.896  62.706  75.778 1.00 183.75 ? 209 ARG A CB  1 
ATOM   370  C CG  . ARG A 1 210 ? 94.683  62.954  74.491 1.00 250.90 ? 209 ARG A CG  1 
ATOM   371  C CD  . ARG A 1 210 ? 93.834  63.009  73.216 1.00 243.61 ? 209 ARG A CD  1 
ATOM   372  N NE  . ARG A 1 210 ? 94.529  63.520  72.041 1.00 238.15 ? 209 ARG A NE  1 
ATOM   373  C CZ  . ARG A 1 210 ? 95.391  62.848  71.283 1.00 329.87 ? 209 ARG A CZ  1 
ATOM   374  N NH1 . ARG A 1 210 ? 95.921  63.442  70.229 1.00 348.68 ? 209 ARG A NH1 1 
ATOM   375  N NH2 . ARG A 1 210 ? 95.724  61.592  71.545 1.00 357.95 ? 209 ARG A NH2 1 
ATOM   376  N N   . CYS A 1 211 ? 90.841  62.635  76.930 1.00 171.84 ? 210 CYS A N   1 
ATOM   377  C CA  . CYS A 1 211 ? 89.875  62.246  77.954 1.00 224.79 ? 210 CYS A CA  1 
ATOM   378  C C   . CYS A 1 211 ? 90.521  61.353  79.023 1.00 223.06 ? 210 CYS A C   1 
ATOM   379  O O   . CYS A 1 211 ? 91.322  60.474  78.686 1.00 256.20 ? 210 CYS A O   1 
ATOM   380  C CB  . CYS A 1 211 ? 88.688  61.477  77.370 1.00 211.46 ? 210 CYS A CB  1 
ATOM   381  S SG  . CYS A 1 211 ? 87.948  62.144  75.862 1.00 218.23 ? 210 CYS A SG  1 
ATOM   382  N N   . ARG A 1 212 ? 90.171  61.547  80.315 1.00 170.83 ? 211 ARG A N   1 
ATOM   383  C CA  . ARG A 1 212 ? 90.573  60.604  81.350 1.00 196.94 ? 211 ARG A CA  1 
ATOM   384  C C   . ARG A 1 212 ? 89.854  59.277  81.078 1.00 186.02 ? 211 ARG A C   1 
ATOM   385  O O   . ARG A 1 212 ? 88.672  59.276  80.735 1.00 204.35 ? 211 ARG A O   1 
ATOM   386  C CB  . ARG A 1 212 ? 90.229  61.186  82.728 1.00 288.31 ? 211 ARG A CB  1 
ATOM   387  C CG  . ARG A 1 212 ? 90.591  60.314  83.924 1.00 327.42 ? 211 ARG A CG  1 
ATOM   388  C CD  . ARG A 1 212 ? 90.025  60.817  85.249 1.00 297.94 ? 211 ARG A CD  1 
ATOM   389  N NE  . ARG A 1 212 ? 90.675  62.040  85.712 1.00 335.00 ? 211 ARG A NE  1 
ATOM   390  C CZ  . ARG A 1 212 ? 91.865  62.121  86.318 1.00 384.40 ? 211 ARG A CZ  1 
ATOM   391  N NH1 . ARG A 1 212 ? 92.403  63.306  86.560 1.00 413.42 ? 211 ARG A NH1 1 
ATOM   392  N NH2 . ARG A 1 212 ? 92.529  61.033  86.676 1.00 404.27 ? 211 ARG A NH2 1 
ATOM   393  N N   . GLU A 1 213 ? 90.541  58.134  81.242 1.00 153.29 ? 212 GLU A N   1 
ATOM   394  C CA  . GLU A 1 213 ? 89.909  56.821  81.066 1.00 175.53 ? 212 GLU A CA  1 
ATOM   395  C C   . GLU A 1 213 ? 88.908  56.547  82.203 1.00 157.02 ? 212 GLU A C   1 
ATOM   396  O O   . GLU A 1 213 ? 89.068  57.042  83.322 1.00 232.54 ? 212 GLU A O   1 
ATOM   397  C CB  . GLU A 1 213 ? 90.969  55.715  80.922 1.00 225.89 ? 212 GLU A CB  1 
ATOM   398  C CG  . GLU A 1 213 ? 91.789  55.367  82.174 1.00 295.20 ? 212 GLU A CG  1 
ATOM   399  C CD  . GLU A 1 213 ? 92.899  56.319  82.612 1.00 338.56 ? 212 GLU A CD  1 
ATOM   400  O OE1 . GLU A 1 213 ? 93.099  57.368  81.953 1.00 298.99 ? 212 GLU A OE1 1 
ATOM   401  O OE2 . GLU A 1 213 ? 93.561  56.013  83.623 1.00 394.88 ? 212 GLU A OE2 1 
ATOM   402  N N   . LEU A 1 214 ? 87.860  55.751  81.948 1.00 131.31 ? 213 LEU A N   1 
ATOM   403  C CA  . LEU A 1 214 ? 86.845  55.529  82.973 1.00 186.31 ? 213 LEU A CA  1 
ATOM   404  C C   . LEU A 1 214 ? 87.444  54.806  84.203 1.00 214.12 ? 213 LEU A C   1 
ATOM   405  O O   . LEU A 1 214 ? 87.295  53.572  84.328 1.00 209.79 ? 213 LEU A O   1 
ATOM   406  C CB  . LEU A 1 214 ? 85.683  54.763  82.334 1.00 197.57 ? 213 LEU A CB  1 
ATOM   407  C CG  . LEU A 1 214 ? 84.936  55.524  81.244 1.00 211.01 ? 213 LEU A CG  1 
ATOM   408  C CD1 . LEU A 1 214 ? 83.885  54.637  80.595 1.00 301.50 ? 213 LEU A CD1 1 
ATOM   409  C CD2 . LEU A 1 214 ? 84.280  56.771  81.806 1.00 218.99 ? 213 LEU A CD2 1 
ATOM   410  N N   . THR B 2 51  ? 61.018  47.295  36.391 1.00 346.12 ? 51  THR B N   1 
ATOM   411  C CA  . THR B 2 51  ? 59.931  46.726  37.245 1.00 391.05 ? 51  THR B CA  1 
ATOM   412  C C   . THR B 2 51  ? 59.827  47.509  38.555 1.00 321.75 ? 51  THR B C   1 
ATOM   413  O O   . THR B 2 51  ? 60.817  48.087  38.994 1.00 276.24 ? 51  THR B O   1 
ATOM   414  C CB  . THR B 2 51  ? 60.139  45.230  37.544 1.00 445.92 ? 51  THR B CB  1 
ATOM   415  O OG1 . THR B 2 51  ? 61.377  45.046  38.235 1.00 422.97 ? 51  THR B OG1 1 
ATOM   416  C CG2 . THR B 2 51  ? 60.133  44.357  36.306 1.00 493.82 ? 51  THR B CG2 1 
ATOM   417  N N   . LEU B 2 52  ? 58.635  47.505  39.182 1.00 310.13 ? 52  LEU B N   1 
ATOM   418  C CA  . LEU B 2 52  ? 58.342  48.288  40.388 1.00 270.75 ? 52  LEU B CA  1 
ATOM   419  C C   . LEU B 2 52  ? 59.295  47.939  41.543 1.00 244.37 ? 52  LEU B C   1 
ATOM   420  O O   . LEU B 2 52  ? 59.751  48.841  42.243 1.00 233.29 ? 52  LEU B O   1 
ATOM   421  C CB  . LEU B 2 52  ? 56.868  48.076  40.771 1.00 299.02 ? 52  LEU B CB  1 
ATOM   422  C CG  . LEU B 2 52  ? 56.382  48.733  42.066 1.00 272.56 ? 52  LEU B CG  1 
ATOM   423  C CD1 . LEU B 2 52  ? 56.450  50.250  41.979 1.00 257.92 ? 52  LEU B CD1 1 
ATOM   424  C CD2 . LEU B 2 52  ? 54.962  48.298  42.401 1.00 273.50 ? 52  LEU B CD2 1 
ATOM   425  N N   . LEU B 2 53  ? 59.613  46.646  41.739 1.00 278.82 ? 53  LEU B N   1 
ATOM   426  C CA  . LEU B 2 53  ? 60.517  46.183  42.794 1.00 319.42 ? 53  LEU B CA  1 
ATOM   427  C C   . LEU B 2 53  ? 61.921  46.814  42.685 1.00 269.73 ? 53  LEU B C   1 
ATOM   428  O O   . LEU B 2 53  ? 62.531  47.120  43.716 1.00 271.43 ? 53  LEU B O   1 
ATOM   429  C CB  . LEU B 2 53  ? 60.569  44.646  42.740 1.00 411.52 ? 53  LEU B CB  1 
ATOM   430  C CG  . LEU B 2 53  ? 61.413  43.941  43.805 1.00 459.17 ? 53  LEU B CG  1 
ATOM   431  C CD1 . LEU B 2 53  ? 60.824  44.127  45.195 1.00 473.69 ? 53  LEU B CD1 1 
ATOM   432  C CD2 . LEU B 2 53  ? 61.548  42.460  43.483 1.00 449.17 ? 53  LEU B CD2 1 
ATOM   433  N N   . ASN B 2 54  ? 62.435  47.014  41.459 1.00 240.41 ? 54  ASN B N   1 
ATOM   434  C CA  . ASN B 2 54  ? 63.712  47.681  41.223 1.00 266.69 ? 54  ASN B CA  1 
ATOM   435  C C   . ASN B 2 54  ? 63.590  49.212  41.324 1.00 234.02 ? 54  ASN B C   1 
ATOM   436  O O   . ASN B 2 54  ? 64.576  49.888  41.620 1.00 235.63 ? 54  ASN B O   1 
ATOM   437  C CB  . ASN B 2 54  ? 64.302  47.248  39.879 1.00 326.17 ? 54  ASN B CB  1 
ATOM   438  C CG  . ASN B 2 54  ? 65.754  47.663  39.714 1.00 302.16 ? 54  ASN B CG  1 
ATOM   439  O OD1 . ASN B 2 54  ? 66.609  47.317  40.531 1.00 225.85 ? 54  ASN B OD1 1 
ATOM   440  N ND2 . ASN B 2 54  ? 66.050  48.412  38.664 1.00 320.09 ? 54  ASN B ND2 1 
ATOM   441  N N   . GLY B 2 55  ? 62.394  49.782  41.093 1.00 221.14 ? 55  GLY B N   1 
ATOM   442  C CA  . GLY B 2 55  ? 62.113  51.187  41.387 1.00 212.98 ? 55  GLY B CA  1 
ATOM   443  C C   . GLY B 2 55  ? 62.260  51.521  42.875 1.00 213.15 ? 55  GLY B C   1 
ATOM   444  O O   . GLY B 2 55  ? 62.953  52.458  43.226 1.00 193.89 ? 55  GLY B O   1 
ATOM   445  N N   . VAL B 2 56  ? 61.640  50.731  43.758 1.00 201.21 ? 56  VAL B N   1 
ATOM   446  C CA  . VAL B 2 56  ? 61.782  50.878  45.206 1.00 162.24 ? 56  VAL B CA  1 
ATOM   447  C C   . VAL B 2 56  ? 63.261  50.824  45.633 1.00 136.03 ? 56  VAL B C   1 
ATOM   448  O O   . VAL B 2 56  ? 63.675  51.588  46.481 1.00 147.64 ? 56  VAL B O   1 
ATOM   449  C CB  . VAL B 2 56  ? 60.917  49.835  45.947 1.00 191.14 ? 56  VAL B CB  1 
ATOM   450  C CG1 . VAL B 2 56  ? 61.168  49.755  47.455 1.00 213.86 ? 56  VAL B CG1 1 
ATOM   451  C CG2 . VAL B 2 56  ? 59.454  50.097  45.681 1.00 167.16 ? 56  VAL B CG2 1 
ATOM   452  N N   . ALA B 2 57  ? 64.083  49.954  45.058 1.00 182.36 ? 57  ALA B N   1 
ATOM   453  C CA  . ALA B 2 57  ? 65.510  49.907  45.358 1.00 211.27 ? 57  ALA B CA  1 
ATOM   454  C C   . ALA B 2 57  ? 66.283  51.173  44.926 1.00 164.47 ? 57  ALA B C   1 
ATOM   455  O O   . ALA B 2 57  ? 67.413  51.371  45.372 1.00 215.52 ? 57  ALA B O   1 
ATOM   456  C CB  . ALA B 2 57  ? 66.084  48.639  44.733 1.00 298.25 ? 57  ALA B CB  1 
ATOM   457  N N   . ILE B 2 58  ? 65.733  52.018  44.034 1.00 159.84 ? 58  ILE B N   1 
ATOM   458  C CA  . ILE B 2 58  ? 66.308  53.314  43.679 1.00 213.36 ? 58  ILE B CA  1 
ATOM   459  C C   . ILE B 2 58  ? 65.842  54.372  44.678 1.00 157.64 ? 58  ILE B C   1 
ATOM   460  O O   . ILE B 2 58  ? 66.679  55.134  45.178 1.00 224.93 ? 58  ILE B O   1 
ATOM   461  C CB  . ILE B 2 58  ? 65.974  53.709  42.213 1.00 319.16 ? 58  ILE B CB  1 
ATOM   462  C CG1 . ILE B 2 58  ? 66.668  52.790  41.192 1.00 353.05 ? 58  ILE B CG1 1 
ATOM   463  C CG2 . ILE B 2 58  ? 66.249  55.184  41.912 1.00 327.82 ? 58  ILE B CG2 1 
ATOM   464  C CD1 . ILE B 2 58  ? 68.192  52.848  41.161 1.00 345.10 ? 58  ILE B CD1 1 
ATOM   465  N N   . ILE B 2 59  ? 64.532  54.439  44.974 1.00 129.78 ? 59  ILE B N   1 
ATOM   466  C CA  . ILE B 2 59  ? 64.033  55.474  45.883 1.00 167.22 ? 59  ILE B CA  1 
ATOM   467  C C   . ILE B 2 59  ? 64.510  55.240  47.345 1.00 150.14 ? 59  ILE B C   1 
ATOM   468  O O   . ILE B 2 59  ? 64.973  56.173  47.981 1.00 153.45 ? 59  ILE B O   1 
ATOM   469  C CB  . ILE B 2 59  ? 62.511  55.748  45.723 1.00 162.12 ? 59  ILE B CB  1 
ATOM   470  C CG1 . ILE B 2 59  ? 62.014  56.768  46.760 1.00 237.40 ? 59  ILE B CG1 1 
ATOM   471  C CG2 . ILE B 2 59  ? 61.687  54.480  45.738 1.00 171.96 ? 59  ILE B CG2 1 
ATOM   472  C CD1 . ILE B 2 59  ? 60.600  57.261  46.516 1.00 199.07 ? 59  ILE B CD1 1 
ATOM   473  N N   . VAL B 2 60  ? 64.459  54.038  47.910 1.00 154.37 ? 60  VAL B N   1 
ATOM   474  C CA  . VAL B 2 60  ? 64.878  53.823  49.299 1.00 160.07 ? 60  VAL B CA  1 
ATOM   475  C C   . VAL B 2 60  ? 66.351  54.214  49.496 1.00 175.13 ? 60  VAL B C   1 
ATOM   476  O O   . VAL B 2 60  ? 66.683  54.865  50.481 1.00 271.19 ? 60  VAL B O   1 
ATOM   477  C CB  . VAL B 2 60  ? 64.593  52.373  49.773 1.00 218.50 ? 60  VAL B CB  1 
ATOM   478  C CG1 . VAL B 2 60  ? 65.600  51.315  49.290 1.00 251.35 ? 60  VAL B CG1 1 
ATOM   479  C CG2 . VAL B 2 60  ? 64.508  52.288  51.278 1.00 169.44 ? 60  VAL B CG2 1 
ATOM   480  N N   . GLY B 2 61  ? 67.250  53.847  48.578 1.00 145.83 ? 61  GLY B N   1 
ATOM   481  C CA  . GLY B 2 61  ? 68.653  54.239  48.609 1.00 189.27 ? 61  GLY B CA  1 
ATOM   482  C C   . GLY B 2 61  ? 68.913  55.734  48.383 1.00 169.29 ? 61  GLY B C   1 
ATOM   483  O O   . GLY B 2 61  ? 69.990  56.225  48.740 1.00 197.55 ? 61  GLY B O   1 
ATOM   484  N N   . THR B 2 62  ? 67.938  56.445  47.793 1.00 148.24 ? 62  THR B N   1 
ATOM   485  C CA  . THR B 2 62  ? 67.968  57.895  47.619 1.00 185.06 ? 62  THR B CA  1 
ATOM   486  C C   . THR B 2 62  ? 67.516  58.620  48.891 1.00 200.61 ? 62  THR B C   1 
ATOM   487  O O   . THR B 2 62  ? 68.142  59.613  49.270 1.00 231.65 ? 62  THR B O   1 
ATOM   488  C CB  . THR B 2 62  ? 67.097  58.325  46.427 1.00 247.21 ? 62  THR B CB  1 
ATOM   489  O OG1 . THR B 2 62  ? 67.620  57.685  45.254 1.00 312.17 ? 62  THR B OG1 1 
ATOM   490  C CG2 . THR B 2 62  ? 66.994  59.831  46.230 1.00 216.69 ? 62  THR B CG2 1 
ATOM   491  N N   . ILE B 2 63  ? 66.442  58.138  49.556 1.00 192.29 ? 63  ILE B N   1 
ATOM   492  C CA  . ILE B 2 63  ? 65.843  58.801  50.717 1.00 180.45 ? 63  ILE B CA  1 
ATOM   493  C C   . ILE B 2 63  ? 66.678  58.637  51.994 1.00 174.36 ? 63  ILE B C   1 
ATOM   494  O O   . ILE B 2 63  ? 66.769  59.599  52.757 1.00 181.79 ? 63  ILE B O   1 
ATOM   495  C CB  . ILE B 2 63  ? 64.394  58.320  50.912 1.00 162.86 ? 63  ILE B CB  1 
ATOM   496  C CG1 . ILE B 2 63  ? 63.485  58.691  49.730 1.00 202.35 ? 63  ILE B CG1 1 
ATOM   497  C CG2 . ILE B 2 63  ? 63.817  58.830  52.214 1.00 225.66 ? 63  ILE B CG2 1 
ATOM   498  C CD1 . ILE B 2 63  ? 63.335  60.198  49.449 1.00 204.22 ? 63  ILE B CD1 1 
ATOM   499  N N   . ILE B 2 64  ? 67.299  57.463  52.226 1.00 168.09 ? 64  ILE B N   1 
ATOM   500  C CA  . ILE B 2 64  ? 67.875  57.108  53.529 1.00 154.62 ? 64  ILE B CA  1 
ATOM   501  C C   . ILE B 2 64  ? 68.941  58.099  54.031 1.00 169.69 ? 64  ILE B C   1 
ATOM   502  O O   . ILE B 2 64  ? 69.021  58.321  55.241 1.00 203.22 ? 64  ILE B O   1 
ATOM   503  C CB  . ILE B 2 64  ? 68.332  55.632  53.535 1.00 128.95 ? 64  ILE B CB  1 
ATOM   504  C CG1 . ILE B 2 64  ? 67.116  54.771  53.892 1.00 181.57 ? 64  ILE B CG1 1 
ATOM   505  C CG2 . ILE B 2 64  ? 69.490  55.349  54.467 1.00 139.84 ? 64  ILE B CG2 1 
ATOM   506  C CD1 . ILE B 2 64  ? 67.334  53.271  53.785 1.00 281.42 ? 64  ILE B CD1 1 
ATOM   507  N N   . GLY B 2 65  ? 69.734  58.715  53.160 1.00 183.41 ? 65  GLY B N   1 
ATOM   508  C CA  . GLY B 2 65  ? 70.553  59.854  53.572 1.00 233.79 ? 65  GLY B CA  1 
ATOM   509  C C   . GLY B 2 65  ? 71.658  59.554  54.599 1.00 229.34 ? 65  GLY B C   1 
ATOM   510  O O   . GLY B 2 65  ? 72.034  58.406  54.834 1.00 219.57 ? 65  GLY B O   1 
ATOM   511  N N   . SER B 2 66  ? 72.202  60.631  55.196 1.00 196.95 ? 66  SER B N   1 
ATOM   512  C CA  . SER B 2 66  ? 73.137  60.552  56.321 1.00 164.34 ? 66  SER B CA  1 
ATOM   513  C C   . SER B 2 66  ? 72.550  61.170  57.592 1.00 155.84 ? 66  SER B C   1 
ATOM   514  O O   . SER B 2 66  ? 73.141  60.997  58.661 1.00 123.42 ? 66  SER B O   1 
ATOM   515  C CB  . SER B 2 66  ? 74.475  61.215  55.999 1.00 153.32 ? 66  SER B CB  1 
ATOM   516  O OG  . SER B 2 66  ? 75.149  60.526  54.981 1.00 151.88 ? 66  SER B OG  1 
ATOM   517  N N   . GLY B 2 67  ? 71.407  61.870  57.505 1.00 146.34 ? 67  GLY B N   1 
ATOM   518  C CA  . GLY B 2 67  ? 70.833  62.495  58.684 1.00 165.00 ? 67  GLY B CA  1 
ATOM   519  C C   . GLY B 2 67  ? 70.498  61.521  59.821 1.00 141.84 ? 67  GLY B C   1 
ATOM   520  O O   . GLY B 2 67  ? 70.415  61.923  60.967 1.00 174.76 ? 67  GLY B O   1 
ATOM   521  N N   . ILE B 2 68  ? 70.270  60.243  59.536 1.00 137.82 ? 68  ILE B N   1 
ATOM   522  C CA  . ILE B 2 68  ? 69.969  59.236  60.544 1.00 141.14 ? 68  ILE B CA  1 
ATOM   523  C C   . ILE B 2 68  ? 71.121  59.068  61.556 1.00 137.73 ? 68  ILE B C   1 
ATOM   524  O O   . ILE B 2 68  ? 70.927  58.503  62.635 1.00 163.38 ? 68  ILE B O   1 
ATOM   525  C CB  . ILE B 2 68  ? 69.591  57.916  59.823 1.00 141.13 ? 68  ILE B CB  1 
ATOM   526  C CG1 . ILE B 2 68  ? 69.031  56.853  60.766 1.00 184.02 ? 68  ILE B CG1 1 
ATOM   527  C CG2 . ILE B 2 68  ? 70.754  57.320  59.032 1.00 119.24 ? 68  ILE B CG2 1 
ATOM   528  C CD1 . ILE B 2 68  ? 67.855  57.301  61.613 1.00 162.11 ? 68  ILE B CD1 1 
ATOM   529  N N   . PHE B 2 69  ? 72.332  59.528  61.243 1.00 126.38 ? 69  PHE B N   1 
ATOM   530  C CA  . PHE B 2 69  ? 73.461  59.408  62.157 1.00 138.79 ? 69  PHE B CA  1 
ATOM   531  C C   . PHE B 2 69  ? 73.629  60.630  63.050 1.00 129.85 ? 69  PHE B C   1 
ATOM   532  O O   . PHE B 2 69  ? 74.347  60.525  64.064 1.00 162.48 ? 69  PHE B O   1 
ATOM   533  C CB  . PHE B 2 69  ? 74.731  59.152  61.336 1.00 154.16 ? 69  PHE B CB  1 
ATOM   534  C CG  . PHE B 2 69  ? 74.627  57.907  60.486 1.00 118.09 ? 69  PHE B CG  1 
ATOM   535  C CD1 . PHE B 2 69  ? 74.409  56.690  61.062 1.00 110.56 ? 69  PHE B CD1 1 
ATOM   536  C CD2 . PHE B 2 69  ? 74.704  57.961  59.115 1.00 159.20 ? 69  PHE B CD2 1 
ATOM   537  C CE1 . PHE B 2 69  ? 74.313  55.544  60.302 1.00 150.20 ? 69  PHE B CE1 1 
ATOM   538  C CE2 . PHE B 2 69  ? 74.611  56.810  58.354 1.00 170.90 ? 69  PHE B CE2 1 
ATOM   539  C CZ  . PHE B 2 69  ? 74.412  55.604  58.951 1.00 144.45 ? 69  PHE B CZ  1 
ATOM   540  N N   . VAL B 2 70  ? 72.977  61.759  62.679 1.00 103.45 ? 70  VAL B N   1 
ATOM   541  C CA  . VAL B 2 70  ? 72.899  62.974  63.488 1.00 153.00 ? 70  VAL B CA  1 
ATOM   542  C C   . VAL B 2 70  ? 71.711  62.911  64.445 1.00 169.90 ? 70  VAL B C   1 
ATOM   543  O O   . VAL B 2 70  ? 71.836  63.085  65.656 1.00 188.40 ? 70  VAL B O   1 
ATOM   544  C CB  . VAL B 2 70  ? 72.753  64.228  62.604 1.00 93.49  ? 70  VAL B CB  1 
ATOM   545  C CG1 . VAL B 2 70  ? 72.683  65.472  63.441 1.00 144.63 ? 70  VAL B CG1 1 
ATOM   546  C CG2 . VAL B 2 70  ? 73.869  64.356  61.612 1.00 162.01 ? 70  VAL B CG2 1 
ATOM   547  N N   . THR B 2 71  ? 70.535  62.672  63.863 1.00 125.01 ? 71  THR B N   1 
ATOM   548  C CA  . THR B 2 71  ? 69.288  63.172  64.411 1.00 122.73 ? 71  THR B CA  1 
ATOM   549  C C   . THR B 2 71  ? 68.708  62.334  65.549 1.00 137.58 ? 71  THR B C   1 
ATOM   550  O O   . THR B 2 71  ? 67.844  62.859  66.236 1.00 146.88 ? 71  THR B O   1 
ATOM   551  C CB  . THR B 2 71  ? 68.269  63.303  63.272 1.00 139.67 ? 71  THR B CB  1 
ATOM   552  O OG1 . THR B 2 71  ? 68.179  62.061  62.565 1.00 164.54 ? 71  THR B OG1 1 
ATOM   553  C CG2 . THR B 2 71  ? 68.622  64.419  62.315 1.00 133.60 ? 71  THR B CG2 1 
ATOM   554  N N   . PRO B 2 72  ? 69.056  61.050  65.822 1.00 129.52 ? 72  PRO B N   1 
ATOM   555  C CA  . PRO B 2 72  ? 68.527  60.339  66.986 1.00 149.97 ? 72  PRO B CA  1 
ATOM   556  C C   . PRO B 2 72  ? 68.678  61.113  68.284 1.00 150.87 ? 72  PRO B C   1 
ATOM   557  O O   . PRO B 2 72  ? 67.719  61.186  69.046 1.00 164.72 ? 72  PRO B O   1 
ATOM   558  C CB  . PRO B 2 72  ? 69.324  59.015  67.014 1.00 163.94 ? 72  PRO B CB  1 
ATOM   559  C CG  . PRO B 2 72  ? 69.585  58.776  65.553 1.00 149.71 ? 72  PRO B CG  1 
ATOM   560  C CD  . PRO B 2 72  ? 69.909  60.166  65.034 1.00 120.72 ? 72  PRO B CD  1 
ATOM   561  N N   . THR B 2 73  ? 69.866  61.691  68.520 1.00 122.57 ? 73  THR B N   1 
ATOM   562  C CA  . THR B 2 73  ? 70.083  62.566  69.666 1.00 149.84 ? 73  THR B CA  1 
ATOM   563  C C   . THR B 2 73  ? 69.149  63.791  69.653 1.00 146.21 ? 73  THR B C   1 
ATOM   564  O O   . THR B 2 73  ? 68.726  64.269  70.703 1.00 140.88 ? 73  THR B O   1 
ATOM   565  C CB  . THR B 2 73  ? 71.553  62.973  69.731 1.00 145.28 ? 73  THR B CB  1 
ATOM   566  O OG1 . THR B 2 73  ? 72.291  61.767  69.943 1.00 147.29 ? 73  THR B OG1 1 
ATOM   567  C CG2 . THR B 2 73  ? 71.865  63.978  70.829 1.00 170.53 ? 73  THR B CG2 1 
ATOM   568  N N   . GLY B 2 74  ? 68.815  64.304  68.464 1.00 115.00 ? 74  GLY B N   1 
ATOM   569  C CA  . GLY B 2 74  ? 67.944  65.452  68.295 1.00 162.70 ? 74  GLY B CA  1 
ATOM   570  C C   . GLY B 2 74  ? 66.506  65.171  68.722 1.00 171.85 ? 74  GLY B C   1 
ATOM   571  O O   . GLY B 2 74  ? 65.950  65.899  69.542 1.00 150.69 ? 74  GLY B O   1 
ATOM   572  N N   . VAL B 2 75  ? 65.901  64.100  68.188 1.00 153.50 ? 75  VAL B N   1 
ATOM   573  C CA  . VAL B 2 75  ? 64.536  63.744  68.562 1.00 143.63 ? 75  VAL B CA  1 
ATOM   574  C C   . VAL B 2 75  ? 64.490  63.339  70.035 1.00 155.49 ? 75  VAL B C   1 
ATOM   575  O O   . VAL B 2 75  ? 63.531  63.685  70.716 1.00 185.30 ? 75  VAL B O   1 
ATOM   576  C CB  . VAL B 2 75  ? 63.914  62.651  67.669 1.00 177.52 ? 75  VAL B CB  1 
ATOM   577  C CG1 . VAL B 2 75  ? 63.872  63.084  66.231 1.00 211.00 ? 75  VAL B CG1 1 
ATOM   578  C CG2 . VAL B 2 75  ? 64.614  61.310  67.743 1.00 177.41 ? 75  VAL B CG2 1 
ATOM   579  N N   . LEU B 2 76  ? 65.494  62.626  70.556 1.00 142.05 ? 76  LEU B N   1 
ATOM   580  C CA  . LEU B 2 76  ? 65.490  62.210  71.952 1.00 136.55 ? 76  LEU B CA  1 
ATOM   581  C C   . LEU B 2 76  ? 65.601  63.407  72.898 1.00 107.48 ? 76  LEU B C   1 
ATOM   582  O O   . LEU B 2 76  ? 64.925  63.415  73.926 1.00 144.51 ? 76  LEU B O   1 
ATOM   583  C CB  . LEU B 2 76  ? 66.616  61.191  72.172 1.00 134.03 ? 76  LEU B CB  1 
ATOM   584  C CG  . LEU B 2 76  ? 66.574  60.468  73.506 1.00 162.56 ? 76  LEU B CG  1 
ATOM   585  C CD1 . LEU B 2 76  ? 65.327  59.569  73.654 1.00 155.81 ? 76  LEU B CD1 1 
ATOM   586  C CD2 . LEU B 2 76  ? 67.846  59.677  73.674 1.00 165.92 ? 76  LEU B CD2 1 
ATOM   587  N N   . LYS B 2 77  ? 66.418  64.417  72.578 1.00 147.47 ? 77  LYS B N   1 
ATOM   588  C CA  . LYS B 2 77  ? 66.553  65.618  73.396 1.00 188.76 ? 77  LYS B CA  1 
ATOM   589  C C   . LYS B 2 77  ? 65.213  66.345  73.563 1.00 168.99 ? 77  LYS B C   1 
ATOM   590  O O   . LYS B 2 77  ? 64.902  66.814  74.667 1.00 230.35 ? 77  LYS B O   1 
ATOM   591  C CB  . LYS B 2 77  ? 67.626  66.531  72.798 1.00 207.88 ? 77  LYS B CB  1 
ATOM   592  C CG  . LYS B 2 77  ? 67.942  67.765  73.626 1.00 269.97 ? 77  LYS B CG  1 
ATOM   593  C CD  . LYS B 2 77  ? 69.209  68.483  73.169 1.00 370.38 ? 77  LYS B CD  1 
ATOM   594  C CE  . LYS B 2 77  ? 69.150  69.094  71.779 1.00 422.83 ? 77  LYS B CE  1 
ATOM   595  N NZ  . LYS B 2 77  ? 68.305  70.315  71.715 1.00 466.03 ? 77  LYS B NZ  1 
ATOM   596  N N   . GLU B 2 78  ? 64.424  66.436  72.480 1.00 114.81 ? 78  GLU B N   1 
ATOM   597  C CA  . GLU B 2 78  ? 63.147  67.147  72.499 1.00 172.09 ? 78  GLU B CA  1 
ATOM   598  C C   . GLU B 2 78  ? 61.954  66.287  72.989 1.00 176.53 ? 78  GLU B C   1 
ATOM   599  O O   . GLU B 2 78  ? 61.081  66.788  73.692 1.00 140.82 ? 78  GLU B O   1 
ATOM   600  C CB  . GLU B 2 78  ? 62.912  67.703  71.100 1.00 191.07 ? 78  GLU B CB  1 
ATOM   601  C CG  . GLU B 2 78  ? 63.998  68.631  70.572 1.00 202.04 ? 78  GLU B CG  1 
ATOM   602  C CD  . GLU B 2 78  ? 64.358  69.799  71.468 1.00 219.76 ? 78  GLU B CD  1 
ATOM   603  O OE1 . GLU B 2 78  ? 63.457  70.333  72.126 1.00 191.55 ? 78  GLU B OE1 1 
ATOM   604  O OE2 . GLU B 2 78  ? 65.545  70.167  71.499 1.00 312.02 ? 78  GLU B OE2 1 
ATOM   605  N N   . ALA B 2 79  ? 61.899  64.994  72.642 1.00 169.46 ? 79  ALA B N   1 
ATOM   606  C CA  . ALA B 2 79  ? 60.867  64.055  73.091 1.00 194.01 ? 79  ALA B CA  1 
ATOM   607  C C   . ALA B 2 79  ? 61.108  63.508  74.512 1.00 195.32 ? 79  ALA B C   1 
ATOM   608  O O   . ALA B 2 79  ? 60.219  62.882  75.108 1.00 222.64 ? 79  ALA B O   1 
ATOM   609  C CB  . ALA B 2 79  ? 60.773  62.924  72.096 1.00 204.78 ? 79  ALA B CB  1 
ATOM   610  N N   . GLY B 2 80  ? 62.299  63.728  75.081 1.00 190.58 ? 80  GLY B N   1 
ATOM   611  C CA  . GLY B 2 80  ? 62.566  63.466  76.492 1.00 249.58 ? 80  GLY B CA  1 
ATOM   612  C C   . GLY B 2 80  ? 62.926  62.013  76.815 1.00 250.28 ? 80  GLY B C   1 
ATOM   613  O O   . GLY B 2 80  ? 63.865  61.780  77.583 1.00 268.58 ? 80  GLY B O   1 
ATOM   614  N N   . SER B 2 81  ? 62.175  61.039  76.256 1.00 174.19 ? 81  SER B N   1 
ATOM   615  C CA  . SER B 2 81  ? 62.376  59.628  76.570 1.00 228.72 ? 81  SER B CA  1 
ATOM   616  C C   . SER B 2 81  ? 61.987  58.743  75.383 1.00 150.33 ? 81  SER B C   1 
ATOM   617  O O   . SER B 2 81  ? 61.133  59.151  74.619 1.00 106.28 ? 81  SER B O   1 
ATOM   618  C CB  . SER B 2 81  ? 61.606  59.285  77.840 1.00 327.97 ? 81  SER B CB  1 
ATOM   619  O OG  . SER B 2 81  ? 61.995  58.046  78.403 1.00 384.31 ? 81  SER B OG  1 
ATOM   620  N N   . PRO B 2 82  ? 62.616  57.547  75.193 1.00 147.96 ? 82  PRO B N   1 
ATOM   621  C CA  . PRO B 2 82  ? 62.497  56.765  73.962 1.00 159.31 ? 82  PRO B CA  1 
ATOM   622  C C   . PRO B 2 82  ? 61.110  56.525  73.380 1.00 173.33 ? 82  PRO B C   1 
ATOM   623  O O   . PRO B 2 82  ? 60.966  56.593  72.170 1.00 141.06 ? 82  PRO B O   1 
ATOM   624  C CB  . PRO B 2 82  ? 63.133  55.415  74.339 1.00 177.73 ? 82  PRO B CB  1 
ATOM   625  C CG  . PRO B 2 82  ? 64.222  55.802  75.293 1.00 188.20 ? 82  PRO B CG  1 
ATOM   626  C CD  . PRO B 2 82  ? 63.549  56.877  76.118 1.00 191.11 ? 82  PRO B CD  1 
ATOM   627  N N   . GLY B 2 83  ? 60.096  56.279  74.211 1.00 216.61 ? 83  GLY B N   1 
ATOM   628  C CA  . GLY B 2 83  ? 58.772  55.899  73.739 1.00 254.30 ? 83  GLY B CA  1 
ATOM   629  C C   . GLY B 2 83  ? 58.190  56.915  72.750 1.00 193.59 ? 83  GLY B C   1 
ATOM   630  O O   . GLY B 2 83  ? 57.625  56.532  71.732 1.00 214.42 ? 83  GLY B O   1 
ATOM   631  N N   . LEU B 2 84  ? 58.330  58.214  73.050 1.00 153.68 ? 84  LEU B N   1 
ATOM   632  C CA  . LEU B 2 84  ? 57.820  59.260  72.177 1.00 150.14 ? 84  LEU B CA  1 
ATOM   633  C C   . LEU B 2 84  ? 58.781  59.507  71.021 1.00 149.60 ? 84  LEU B C   1 
ATOM   634  O O   . LEU B 2 84  ? 58.342  59.913  69.953 1.00 204.41 ? 84  LEU B O   1 
ATOM   635  C CB  . LEU B 2 84  ? 57.562  60.524  73.007 1.00 168.19 ? 84  LEU B CB  1 
ATOM   636  C CG  . LEU B 2 84  ? 56.923  61.706  72.277 1.00 167.47 ? 84  LEU B CG  1 
ATOM   637  C CD1 . LEU B 2 84  ? 55.632  61.343  71.531 1.00 232.18 ? 84  LEU B CD1 1 
ATOM   638  C CD2 . LEU B 2 84  ? 56.599  62.796  73.269 1.00 188.54 ? 84  LEU B CD2 1 
ATOM   639  N N   . ALA B 2 85  ? 60.085  59.262  71.167 1.00 157.41 ? 85  ALA B N   1 
ATOM   640  C CA  . ALA B 2 85  ? 61.022  59.384  70.054 1.00 159.58 ? 85  ALA B CA  1 
ATOM   641  C C   . ALA B 2 85  ? 60.671  58.427  68.909 1.00 153.29 ? 85  ALA B C   1 
ATOM   642  O O   . ALA B 2 85  ? 60.702  58.858  67.745 1.00 165.06 ? 85  ALA B O   1 
ATOM   643  C CB  . ALA B 2 85  ? 62.433  59.184  70.549 1.00 201.61 ? 85  ALA B CB  1 
ATOM   644  N N   . LEU B 2 86  ? 60.323  57.158  69.201 1.00 120.24 ? 86  LEU B N   1 
ATOM   645  C CA  . LEU B 2 86  ? 59.876  56.232  68.160 1.00 140.47 ? 86  LEU B CA  1 
ATOM   646  C C   . LEU B 2 86  ? 58.575  56.697  67.480 1.00 144.24 ? 86  LEU B C   1 
ATOM   647  O O   . LEU B 2 86  ? 58.465  56.586  66.261 1.00 151.53 ? 86  LEU B O   1 
ATOM   648  C CB  . LEU B 2 86  ? 59.726  54.828  68.739 1.00 182.55 ? 86  LEU B CB  1 
ATOM   649  C CG  . LEU B 2 86  ? 60.987  54.196  69.334 1.00 197.52 ? 86  LEU B CG  1 
ATOM   650  C CD1 . LEU B 2 86  ? 60.630  52.895  70.025 1.00 273.86 ? 86  LEU B CD1 1 
ATOM   651  C CD2 . LEU B 2 86  ? 62.064  53.939  68.313 1.00 128.35 ? 86  LEU B CD2 1 
ATOM   652  N N   . VAL B 2 87  ? 57.609  57.244  68.228 1.00 132.40 ? 87  VAL B N   1 
ATOM   653  C CA  . VAL B 2 87  ? 56.388  57.803  67.662 1.00 153.32 ? 87  VAL B CA  1 
ATOM   654  C C   . VAL B 2 87  ? 56.709  58.985  66.743 1.00 152.38 ? 87  VAL B C   1 
ATOM   655  O O   . VAL B 2 87  ? 56.091  59.122  65.690 1.00 220.30 ? 87  VAL B O   1 
ATOM   656  C CB  . VAL B 2 87  ? 55.369  58.170  68.760 1.00 215.46 ? 87  VAL B CB  1 
ATOM   657  C CG1 . VAL B 2 87  ? 54.178  58.993  68.265 1.00 283.51 ? 87  VAL B CG1 1 
ATOM   658  C CG2 . VAL B 2 87  ? 54.878  56.900  69.444 1.00 299.74 ? 87  VAL B CG2 1 
ATOM   659  N N   . VAL B 2 88  ? 57.668  59.840  67.097 1.00 144.41 ? 88  VAL B N   1 
ATOM   660  C CA  . VAL B 2 88  ? 58.084  60.930  66.226 1.00 165.94 ? 88  VAL B CA  1 
ATOM   661  C C   . VAL B 2 88  ? 58.729  60.369  64.962 1.00 141.30 ? 88  VAL B C   1 
ATOM   662  O O   . VAL B 2 88  ? 58.461  60.893  63.884 1.00 225.72 ? 88  VAL B O   1 
ATOM   663  C CB  . VAL B 2 88  ? 58.992  61.945  66.949 1.00 199.03 ? 88  VAL B CB  1 
ATOM   664  C CG1 . VAL B 2 88  ? 59.718  62.907  66.010 1.00 166.95 ? 88  VAL B CG1 1 
ATOM   665  C CG2 . VAL B 2 88  ? 58.161  62.730  67.955 1.00 227.40 ? 88  VAL B CG2 1 
ATOM   666  N N   . TRP B 2 89  ? 59.548  59.332  65.034 1.00 109.37 ? 89  TRP B N   1 
ATOM   667  C CA  . TRP B 2 89  ? 60.096  58.739  63.816 1.00 171.89 ? 89  TRP B CA  1 
ATOM   668  C C   . TRP B 2 89  ? 59.012  58.236  62.869 1.00 186.29 ? 89  TRP B C   1 
ATOM   669  O O   . TRP B 2 89  ? 59.143  58.424  61.657 1.00 234.19 ? 89  TRP B O   1 
ATOM   670  C CB  . TRP B 2 89  ? 61.077  57.596  64.118 1.00 167.03 ? 89  TRP B CB  1 
ATOM   671  C CG  . TRP B 2 89  ? 62.444  58.107  64.424 1.00 160.13 ? 89  TRP B CG  1 
ATOM   672  C CD1 . TRP B 2 89  ? 63.069  58.063  65.623 1.00 183.53 ? 89  TRP B CD1 1 
ATOM   673  C CD2 . TRP B 2 89  ? 63.348  58.768  63.521 1.00 168.49 ? 89  TRP B CD2 1 
ATOM   674  N NE1 . TRP B 2 89  ? 64.304  58.638  65.531 1.00 183.37 ? 89  TRP B NE1 1 
ATOM   675  C CE2 . TRP B 2 89  ? 64.511  59.087  64.248 1.00 188.94 ? 89  TRP B CE2 1 
ATOM   676  C CE3 . TRP B 2 89  ? 63.294  59.114  62.174 1.00 158.74 ? 89  TRP B CE3 1 
ATOM   677  C CZ2 . TRP B 2 89  ? 65.606  59.740  63.664 1.00 166.50 ? 89  TRP B CZ2 1 
ATOM   678  C CZ3 . TRP B 2 89  ? 64.374  59.735  61.589 1.00 152.63 ? 89  TRP B CZ3 1 
ATOM   679  C CH2 . TRP B 2 89  ? 65.508  60.061  62.331 1.00 143.82 ? 89  TRP B CH2 1 
ATOM   680  N N   . ALA B 2 90  ? 57.963  57.609  63.410 1.00 139.20 ? 90  ALA B N   1 
ATOM   681  C CA  . ALA B 2 90  ? 56.834  57.175  62.608 1.00 179.80 ? 90  ALA B CA  1 
ATOM   682  C C   . ALA B 2 90  ? 56.108  58.385  62.015 1.00 148.10 ? 90  ALA B C   1 
ATOM   683  O O   . ALA B 2 90  ? 55.792  58.379  60.824 1.00 225.73 ? 90  ALA B O   1 
ATOM   684  C CB  . ALA B 2 90  ? 55.921  56.297  63.444 1.00 236.83 ? 90  ALA B CB  1 
ATOM   685  N N   . ALA B 2 91  ? 55.829  59.416  62.819 1.00 120.74 ? 91  ALA B N   1 
ATOM   686  C CA  . ALA B 2 91  ? 55.114  60.609  62.376 1.00 180.02 ? 91  ALA B CA  1 
ATOM   687  C C   . ALA B 2 91  ? 55.850  61.310  61.234 1.00 176.37 ? 91  ALA B C   1 
ATOM   688  O O   . ALA B 2 91  ? 55.213  61.776  60.290 1.00 226.10 ? 91  ALA B O   1 
ATOM   689  C CB  . ALA B 2 91  ? 54.892  61.533  63.554 1.00 247.72 ? 91  ALA B CB  1 
ATOM   690  N N   . CYS B 2 92  ? 57.181  61.356  61.303 1.00 167.22 ? 92  CYS B N   1 
ATOM   691  C CA  . CYS B 2 92  ? 58.011  61.882  60.227 1.00 173.88 ? 92  CYS B CA  1 
ATOM   692  C C   . CYS B 2 92  ? 57.907  61.055  58.946 1.00 158.09 ? 92  CYS B C   1 
ATOM   693  O O   . CYS B 2 92  ? 57.855  61.627  57.845 1.00 134.92 ? 92  CYS B O   1 
ATOM   694  C CB  . CYS B 2 92  ? 59.439  61.968  60.720 1.00 151.58 ? 92  CYS B CB  1 
ATOM   695  S SG  . CYS B 2 92  ? 59.512  63.155  62.070 1.00 229.80 ? 92  CYS B SG  1 
ATOM   696  N N   . GLY B 2 93  ? 57.847  59.724  59.091 1.00 125.21 ? 93  GLY B N   1 
ATOM   697  C CA  . GLY B 2 93  ? 57.552  58.842  57.973 1.00 141.72 ? 93  GLY B CA  1 
ATOM   698  C C   . GLY B 2 93  ? 56.226  59.189  57.288 1.00 152.93 ? 93  GLY B C   1 
ATOM   699  O O   . GLY B 2 93  ? 56.206  59.396  56.073 1.00 140.00 ? 93  GLY B O   1 
ATOM   700  N N   . VAL B 2 94  ? 55.139  59.257  58.073 1.00 148.29 ? 94  VAL B N   1 
ATOM   701  C CA  . VAL B 2 94  ? 53.806  59.522  57.559 1.00 138.95 ? 94  VAL B CA  1 
ATOM   702  C C   . VAL B 2 94  ? 53.763  60.903  56.908 1.00 134.51 ? 94  VAL B C   1 
ATOM   703  O O   . VAL B 2 94  ? 53.179  61.026  55.838 1.00 148.96 ? 94  VAL B O   1 
ATOM   704  C CB  . VAL B 2 94  ? 52.735  59.319  58.648 1.00 216.03 ? 94  VAL B CB  1 
ATOM   705  C CG1 . VAL B 2 94  ? 51.337  59.798  58.252 1.00 288.45 ? 94  VAL B CG1 1 
ATOM   706  C CG2 . VAL B 2 94  ? 52.705  57.842  59.037 1.00 282.43 ? 94  VAL B CG2 1 
ATOM   707  N N   . PHE B 2 95  ? 54.367  61.931  57.513 1.00 133.52 ? 95  PHE B N   1 
ATOM   708  C CA  . PHE B 2 95  ? 54.469  63.239  56.874 1.00 130.19 ? 95  PHE B CA  1 
ATOM   709  C C   . PHE B 2 95  ? 55.213  63.176  55.543 1.00 123.59 ? 95  PHE B C   1 
ATOM   710  O O   . PHE B 2 95  ? 54.781  63.801  54.577 1.00 117.62 ? 95  PHE B O   1 
ATOM   711  C CB  . PHE B 2 95  ? 55.139  64.206  57.822 1.00 126.08 ? 95  PHE B CB  1 
ATOM   712  C CG  . PHE B 2 95  ? 55.297  65.624  57.334 1.00 156.05 ? 95  PHE B CG  1 
ATOM   713  C CD1 . PHE B 2 95  ? 56.361  65.966  56.509 1.00 162.65 ? 95  PHE B CD1 1 
ATOM   714  C CD2 . PHE B 2 95  ? 54.400  66.630  57.723 1.00 187.83 ? 95  PHE B CD2 1 
ATOM   715  C CE1 . PHE B 2 95  ? 56.526  67.282  56.094 1.00 181.36 ? 95  PHE B CE1 1 
ATOM   716  C CE2 . PHE B 2 95  ? 54.567  67.947  57.291 1.00 177.90 ? 95  PHE B CE2 1 
ATOM   717  C CZ  . PHE B 2 95  ? 55.627  68.272  56.465 1.00 200.57 ? 95  PHE B CZ  1 
ATOM   718  N N   . SER B 2 96  ? 56.288  62.392  55.463 1.00 129.79 ? 96  SER B N   1 
ATOM   719  C CA  . SER B 2 96  ? 57.004  62.200  54.199 1.00 155.86 ? 96  SER B CA  1 
ATOM   720  C C   . SER B 2 96  ? 56.157  61.482  53.140 1.00 173.01 ? 96  SER B C   1 
ATOM   721  O O   . SER B 2 96  ? 56.269  61.844  51.970 1.00 112.96 ? 96  SER B O   1 
ATOM   722  C CB  . SER B 2 96  ? 58.305  61.488  54.418 1.00 170.94 ? 96  SER B CB  1 
ATOM   723  O OG  . SER B 2 96  ? 59.100  62.236  55.314 1.00 202.63 ? 96  SER B OG  1 
ATOM   724  N N   . ILE B 2 97  ? 55.315  60.492  53.505 1.00 179.41 ? 97  ILE B N   1 
ATOM   725  C CA  . ILE B 2 97  ? 54.416  59.840  52.550 1.00 154.23 ? 97  ILE B CA  1 
ATOM   726  C C   . ILE B 2 97  ? 53.461  60.865  51.933 1.00 140.89 ? 97  ILE B C   1 
ATOM   727  O O   . ILE B 2 97  ? 53.317  60.900  50.707 1.00 160.24 ? 97  ILE B O   1 
ATOM   728  C CB  . ILE B 2 97  ? 53.672  58.663  53.192 1.00 207.48 ? 97  ILE B CB  1 
ATOM   729  C CG1 . ILE B 2 97  ? 54.610  57.488  53.459 1.00 188.90 ? 97  ILE B CG1 1 
ATOM   730  C CG2 . ILE B 2 97  ? 52.490  58.209  52.338 1.00 302.27 ? 97  ILE B CG2 1 
ATOM   731  C CD1 . ILE B 2 97  ? 54.094  56.523  54.514 1.00 272.48 ? 97  ILE B CD1 1 
ATOM   732  N N   . VAL B 2 98  ? 52.838  61.708  52.762 1.00 100.88 ? 98  VAL B N   1 
ATOM   733  C CA  . VAL B 2 98  ? 51.964  62.760  52.256 1.00 142.27 ? 98  VAL B CA  1 
ATOM   734  C C   . VAL B 2 98  ? 52.724  63.813  51.427 1.00 136.35 ? 98  VAL B C   1 
ATOM   735  O O   . VAL B 2 98  ? 52.218  64.284  50.420 1.00 181.99 ? 98  VAL B O   1 
ATOM   736  C CB  . VAL B 2 98  ? 51.149  63.381  53.403 1.00 201.94 ? 98  VAL B CB  1 
ATOM   737  C CG1 . VAL B 2 98  ? 50.174  64.427  52.900 1.00 253.97 ? 98  VAL B CG1 1 
ATOM   738  C CG2 . VAL B 2 98  ? 50.354  62.298  54.146 1.00 219.91 ? 98  VAL B CG2 1 
ATOM   739  N N   . GLY B 2 99  ? 53.931  64.194  51.830 1.00 101.94 ? 99  GLY B N   1 
ATOM   740  C CA  . GLY B 2 99  ? 54.780  65.104  51.065 1.00 117.94 ? 99  GLY B CA  1 
ATOM   741  C C   . GLY B 2 99  ? 55.202  64.550  49.704 1.00 128.78 ? 99  GLY B C   1 
ATOM   742  O O   . GLY B 2 99  ? 55.062  65.229  48.682 1.00 147.25 ? 99  GLY B O   1 
ATOM   743  N N   . ALA B 2 100 ? 55.684  63.300  49.683 1.00 126.23 ? 100 ALA B N   1 
ATOM   744  C CA  . ALA B 2 100 ? 56.174  62.641  48.478 1.00 152.37 ? 100 ALA B CA  1 
ATOM   745  C C   . ALA B 2 100 ? 55.061  62.497  47.431 1.00 189.42 ? 100 ALA B C   1 
ATOM   746  O O   . ALA B 2 100 ? 55.327  62.761  46.256 1.00 183.14 ? 100 ALA B O   1 
ATOM   747  C CB  . ALA B 2 100 ? 56.778  61.292  48.823 1.00 125.21 ? 100 ALA B CB  1 
ATOM   748  N N   . LEU B 2 101 ? 53.827  62.092  47.804 1.00 160.55 ? 101 LEU B N   1 
ATOM   749  C CA  . LEU B 2 101 ? 52.780  61.935  46.808 1.00 150.93 ? 101 LEU B CA  1 
ATOM   750  C C   . LEU B 2 101 ? 52.363  63.302  46.237 1.00 151.22 ? 101 LEU B C   1 
ATOM   751  O O   . LEU B 2 101 ? 51.988  63.365  45.048 1.00 251.58 ? 101 LEU B O   1 
ATOM   752  C CB  . LEU B 2 101 ? 51.610  61.113  47.365 1.00 184.40 ? 101 LEU B CB  1 
ATOM   753  C CG  . LEU B 2 101 ? 50.820  61.642  48.565 1.00 228.28 ? 101 LEU B CG  1 
ATOM   754  C CD1 . LEU B 2 101 ? 49.707  62.642  48.181 1.00 171.14 ? 101 LEU B CD1 1 
ATOM   755  C CD2 . LEU B 2 101 ? 50.221  60.454  49.310 1.00 326.44 ? 101 LEU B CD2 1 
ATOM   756  N N   . CYS B 2 102 ? 52.419  64.401  47.009 1.00 127.08 ? 102 CYS B N   1 
ATOM   757  C CA  . CYS B 2 102 ? 52.169  65.728  46.435 1.00 157.47 ? 102 CYS B CA  1 
ATOM   758  C C   . CYS B 2 102 ? 53.261  66.107  45.433 1.00 139.43 ? 102 CYS B C   1 
ATOM   759  O O   . CYS B 2 102 ? 53.004  66.739  44.408 1.00 177.69 ? 102 CYS B O   1 
ATOM   760  C CB  . CYS B 2 102 ? 51.993  66.764  47.534 1.00 133.88 ? 102 CYS B CB  1 
ATOM   761  S SG  . CYS B 2 102 ? 50.597  66.313  48.601 1.00 242.66 ? 102 CYS B SG  1 
ATOM   762  N N   . TYR B 2 103 ? 54.498  65.703  45.712 1.00 157.99 ? 103 TYR B N   1 
ATOM   763  C CA  . TYR B 2 103 ? 55.602  65.910  44.784 1.00 180.13 ? 103 TYR B CA  1 
ATOM   764  C C   . TYR B 2 103 ? 55.592  64.921  43.611 1.00 215.41 ? 103 TYR B C   1 
ATOM   765  O O   . TYR B 2 103 ? 56.198  65.220  42.581 1.00 279.99 ? 103 TYR B O   1 
ATOM   766  C CB  . TYR B 2 103 ? 56.912  65.878  45.569 1.00 209.63 ? 103 TYR B CB  1 
ATOM   767  C CG  . TYR B 2 103 ? 57.288  67.310  45.892 1.00 213.54 ? 103 TYR B CG  1 
ATOM   768  C CD1 . TYR B 2 103 ? 56.570  68.071  46.828 1.00 217.72 ? 103 TYR B CD1 1 
ATOM   769  C CD2 . TYR B 2 103 ? 58.359  67.896  45.251 1.00 211.45 ? 103 TYR B CD2 1 
ATOM   770  C CE1 . TYR B 2 103 ? 56.906  69.391  47.120 1.00 139.22 ? 103 TYR B CE1 1 
ATOM   771  C CE2 . TYR B 2 103 ? 58.717  69.200  45.547 1.00 211.99 ? 103 TYR B CE2 1 
ATOM   772  C CZ  . TYR B 2 103 ? 57.997  69.946  46.479 1.00 166.34 ? 103 TYR B CZ  1 
ATOM   773  O OH  . TYR B 2 103 ? 58.390  71.224  46.733 1.00 197.81 ? 103 TYR B OH  1 
ATOM   774  N N   . ALA B 2 104 ? 54.931  63.761  43.723 1.00 153.35 ? 104 ALA B N   1 
ATOM   775  C CA  . ALA B 2 104 ? 54.635  62.927  42.567 1.00 202.59 ? 104 ALA B CA  1 
ATOM   776  C C   . ALA B 2 104 ? 53.710  63.664  41.592 1.00 202.25 ? 104 ALA B C   1 
ATOM   777  O O   . ALA B 2 104 ? 53.878  63.530  40.373 1.00 184.27 ? 104 ALA B O   1 
ATOM   778  C CB  . ALA B 2 104 ? 54.030  61.619  43.026 1.00 263.11 ? 104 ALA B CB  1 
ATOM   779  N N   . GLU B 2 105 ? 52.739  64.437  42.121 1.00 179.67 ? 105 GLU B N   1 
ATOM   780  C CA  . GLU B 2 105 ? 51.898  65.288  41.290 1.00 189.58 ? 105 GLU B CA  1 
ATOM   781  C C   . GLU B 2 105 ? 52.739  66.403  40.645 1.00 182.10 ? 105 GLU B C   1 
ATOM   782  O O   . GLU B 2 105 ? 52.882  66.410  39.418 1.00 261.49 ? 105 GLU B O   1 
ATOM   783  C CB  . GLU B 2 105 ? 50.667  65.794  42.050 1.00 153.90 ? 105 GLU B CB  1 
ATOM   784  C CG  . GLU B 2 105 ? 49.724  66.578  41.125 1.00 250.66 ? 105 GLU B CG  1 
ATOM   785  C CD  . GLU B 2 105 ? 48.261  66.658  41.526 1.00 309.07 ? 105 GLU B CD  1 
ATOM   786  O OE1 . GLU B 2 105 ? 47.796  65.732  42.235 1.00 324.19 ? 105 GLU B OE1 1 
ATOM   787  O OE2 . GLU B 2 105 ? 47.573  67.643  41.134 1.00 356.89 ? 105 GLU B OE2 1 
ATOM   788  N N   . LEU B 2 106 ? 53.322  67.329  41.412 1.00 137.04 ? 106 LEU B N   1 
ATOM   789  C CA  . LEU B 2 106 ? 54.081  68.421  40.798 1.00 174.87 ? 106 LEU B CA  1 
ATOM   790  C C   . LEU B 2 106 ? 55.207  67.936  39.860 1.00 210.65 ? 106 LEU B C   1 
ATOM   791  O O   . LEU B 2 106 ? 55.439  68.536  38.806 1.00 210.80 ? 106 LEU B O   1 
ATOM   792  C CB  . LEU B 2 106 ? 54.651  69.328  41.889 1.00 196.86 ? 106 LEU B CB  1 
ATOM   793  C CG  . LEU B 2 106 ? 53.653  70.273  42.551 1.00 218.88 ? 106 LEU B CG  1 
ATOM   794  C CD1 . LEU B 2 106 ? 54.359  71.031  43.663 1.00 257.74 ? 106 LEU B CD1 1 
ATOM   795  C CD2 . LEU B 2 106 ? 53.015  71.245  41.556 1.00 174.29 ? 106 LEU B CD2 1 
ATOM   796  N N   . GLY B 2 107 ? 55.886  66.839  40.216 1.00 242.58 ? 107 GLY B N   1 
ATOM   797  C CA  . GLY B 2 107 ? 56.919  66.219  39.393 1.00 304.24 ? 107 GLY B CA  1 
ATOM   798  C C   . GLY B 2 107 ? 56.448  65.539  38.105 1.00 301.41 ? 107 GLY B C   1 
ATOM   799  O O   . GLY B 2 107 ? 57.286  65.007  37.375 1.00 296.08 ? 107 GLY B O   1 
ATOM   800  N N   . THR B 2 108 ? 55.130  65.531  37.833 1.00 290.43 ? 108 THR B N   1 
ATOM   801  C CA  . THR B 2 108 ? 54.561  65.001  36.598 1.00 264.70 ? 108 THR B CA  1 
ATOM   802  C C   . THR B 2 108 ? 53.590  65.964  35.902 1.00 230.15 ? 108 THR B C   1 
ATOM   803  O O   . THR B 2 108 ? 53.356  65.769  34.706 1.00 309.20 ? 108 THR B O   1 
ATOM   804  C CB  . THR B 2 108 ? 53.855  63.656  36.837 1.00 270.58 ? 108 THR B CB  1 
ATOM   805  O OG1 . THR B 2 108 ? 52.804  63.806  37.793 1.00 177.82 ? 108 THR B OG1 1 
ATOM   806  C CG2 . THR B 2 108 ? 54.800  62.567  37.301 1.00 310.51 ? 108 THR B CG2 1 
ATOM   807  N N   . THR B 2 109 ? 53.024  66.978  36.587 1.00 202.08 ? 109 THR B N   1 
ATOM   808  C CA  . THR B 2 109 ? 52.155  67.953  35.932 1.00 260.45 ? 109 THR B CA  1 
ATOM   809  C C   . THR B 2 109 ? 52.951  69.062  35.237 1.00 272.27 ? 109 THR B C   1 
ATOM   810  O O   . THR B 2 109 ? 52.728  69.309  34.049 1.00 334.16 ? 109 THR B O   1 
ATOM   811  C CB  . THR B 2 109 ? 51.128  68.569  36.891 1.00 247.94 ? 109 THR B CB  1 
ATOM   812  O OG1 . THR B 2 109 ? 51.761  69.271  37.955 1.00 210.38 ? 109 THR B OG1 1 
ATOM   813  C CG2 . THR B 2 109 ? 50.219  67.529  37.501 1.00 284.54 ? 109 THR B CG2 1 
ATOM   814  N N   . ILE B 2 110 ? 53.854  69.745  35.964 1.00 218.05 ? 110 ILE B N   1 
ATOM   815  C CA  . ILE B 2 110 ? 54.640  70.842  35.399 1.00 248.47 ? 110 ILE B CA  1 
ATOM   816  C C   . ILE B 2 110 ? 55.880  70.295  34.671 1.00 260.30 ? 110 ILE B C   1 
ATOM   817  O O   . ILE B 2 110 ? 56.221  70.793  33.589 1.00 186.93 ? 110 ILE B O   1 
ATOM   818  C CB  . ILE B 2 110 ? 54.966  71.892  36.489 1.00 261.80 ? 110 ILE B CB  1 
ATOM   819  C CG1 . ILE B 2 110 ? 53.681  72.536  37.028 1.00 295.57 ? 110 ILE B CG1 1 
ATOM   820  C CG2 . ILE B 2 110 ? 55.921  72.962  35.971 1.00 289.63 ? 110 ILE B CG2 1 
ATOM   821  C CD1 . ILE B 2 110 ? 53.854  73.465  38.221 1.00 331.92 ? 110 ILE B CD1 1 
ATOM   822  N N   . SER B 2 111 ? 56.563  69.306  35.287 1.00 305.18 ? 111 SER B N   1 
ATOM   823  C CA  . SER B 2 111 ? 57.673  68.529  34.716 1.00 338.66 ? 111 SER B CA  1 
ATOM   824  C C   . SER B 2 111 ? 58.913  69.330  34.255 1.00 392.02 ? 111 SER B C   1 
ATOM   825  O O   . SER B 2 111 ? 59.885  68.723  33.797 1.00 409.91 ? 111 SER B O   1 
ATOM   826  C CB  . SER B 2 111 ? 57.154  67.628  33.616 1.00 306.02 ? 111 SER B CB  1 
ATOM   827  O OG  . SER B 2 111 ? 56.260  66.684  34.171 1.00 293.97 ? 111 SER B OG  1 
ATOM   828  N N   . LYS B 2 112 ? 58.931  70.672  34.381 1.00 371.55 ? 112 LYS B N   1 
ATOM   829  C CA  . LYS B 2 112 ? 60.071  71.500  33.990 1.00 323.05 ? 112 LYS B CA  1 
ATOM   830  C C   . LYS B 2 112 ? 61.302  71.154  34.846 1.00 348.34 ? 112 LYS B C   1 
ATOM   831  O O   . LYS B 2 112 ? 61.206  71.037  36.061 1.00 347.63 ? 112 LYS B O   1 
ATOM   832  C CB  . LYS B 2 112 ? 59.698  72.984  34.114 1.00 249.36 ? 112 LYS B CB  1 
ATOM   833  C CG  . LYS B 2 112 ? 60.662  73.942  33.432 1.00 274.92 ? 112 LYS B CG  1 
ATOM   834  C CD  . LYS B 2 112 ? 60.504  75.416  33.822 1.00 352.54 ? 112 LYS B CD  1 
ATOM   835  C CE  . LYS B 2 112 ? 59.104  75.996  33.729 1.00 393.48 ? 112 LYS B CE  1 
ATOM   836  N NZ  . LYS B 2 112 ? 58.629  76.136  32.330 1.00 423.34 ? 112 LYS B NZ  1 
ATOM   837  N N   . SER B 2 113 ? 62.473  70.980  34.210 1.00 362.92 ? 113 SER B N   1 
ATOM   838  C CA  . SER B 2 113 ? 63.700  70.561  34.891 1.00 364.80 ? 113 SER B CA  1 
ATOM   839  C C   . SER B 2 113 ? 64.270  71.635  35.832 1.00 322.03 ? 113 SER B C   1 
ATOM   840  O O   . SER B 2 113 ? 64.134  72.829  35.554 1.00 189.35 ? 113 SER B O   1 
ATOM   841  C CB  . SER B 2 113 ? 64.753  70.169  33.880 1.00 399.26 ? 113 SER B CB  1 
ATOM   842  O OG  . SER B 2 113 ? 64.246  69.213  32.958 1.00 399.54 ? 113 SER B OG  1 
ATOM   843  N N   . GLY B 2 114 ? 64.923  71.191  36.931 1.00 350.35 ? 114 GLY B N   1 
ATOM   844  C CA  . GLY B 2 114 ? 65.748  72.034  37.797 1.00 329.61 ? 114 GLY B CA  1 
ATOM   845  C C   . GLY B 2 114 ? 65.314  72.145  39.261 1.00 336.09 ? 114 GLY B C   1 
ATOM   846  O O   . GLY B 2 114 ? 65.959  72.888  40.009 1.00 265.17 ? 114 GLY B O   1 
ATOM   847  N N   . GLY B 2 115 ? 64.249  71.421  39.659 1.00 375.18 ? 115 GLY B N   1 
ATOM   848  C CA  . GLY B 2 115 ? 63.720  71.438  41.023 1.00 352.66 ? 115 GLY B CA  1 
ATOM   849  C C   . GLY B 2 115 ? 62.627  72.492  41.218 1.00 289.58 ? 115 GLY B C   1 
ATOM   850  O O   . GLY B 2 115 ? 62.122  73.049  40.249 1.00 255.13 ? 115 GLY B O   1 
ATOM   851  N N   . ASP B 2 116 ? 62.269  72.788  42.480 1.00 275.99 ? 116 ASP B N   1 
ATOM   852  C CA  . ASP B 2 116 ? 61.143  73.651  42.843 1.00 277.51 ? 116 ASP B CA  1 
ATOM   853  C C   . ASP B 2 116 ? 61.092  74.994  42.098 1.00 312.91 ? 116 ASP B C   1 
ATOM   854  O O   . ASP B 2 116 ? 60.009  75.466  41.740 1.00 307.63 ? 116 ASP B O   1 
ATOM   855  C CB  . ASP B 2 116 ? 61.171  73.996  44.332 1.00 283.93 ? 116 ASP B CB  1 
ATOM   856  C CG  . ASP B 2 116 ? 60.881  72.867  45.299 1.00 313.08 ? 116 ASP B CG  1 
ATOM   857  O OD1 . ASP B 2 116 ? 60.180  71.938  44.884 1.00 344.13 ? 116 ASP B OD1 1 
ATOM   858  O OD2 . ASP B 2 116 ? 61.362  72.946  46.460 1.00 302.81 ? 116 ASP B OD2 1 
ATOM   859  N N   . TYR B 2 117 ? 62.254  75.622  41.875 1.00 308.93 ? 117 TYR B N   1 
ATOM   860  C CA  . TYR B 2 117 ? 62.343  76.878  41.135 1.00 292.52 ? 117 TYR B CA  1 
ATOM   861  C C   . TYR B 2 117 ? 61.649  76.793  39.771 1.00 273.27 ? 117 TYR B C   1 
ATOM   862  O O   . TYR B 2 117 ? 60.955  77.723  39.377 1.00 283.97 ? 117 TYR B O   1 
ATOM   863  C CB  . TYR B 2 117 ? 63.826  77.218  41.019 1.00 271.04 ? 117 TYR B CB  1 
ATOM   864  C CG  . TYR B 2 117 ? 64.160  78.329  40.043 1.00 230.12 ? 117 TYR B CG  1 
ATOM   865  C CD1 . TYR B 2 117 ? 63.967  79.661  40.364 1.00 204.02 ? 117 TYR B CD1 1 
ATOM   866  C CD2 . TYR B 2 117 ? 64.666  78.033  38.790 1.00 203.64 ? 117 TYR B CD2 1 
ATOM   867  C CE1 . TYR B 2 117 ? 64.291  80.676  39.468 1.00 203.32 ? 117 TYR B CE1 1 
ATOM   868  C CE2 . TYR B 2 117 ? 64.994  79.032  37.884 1.00 223.31 ? 117 TYR B CE2 1 
ATOM   869  C CZ  . TYR B 2 117 ? 64.794  80.360  38.216 1.00 238.25 ? 117 TYR B CZ  1 
ATOM   870  O OH  . TYR B 2 117 ? 65.125  81.324  37.307 1.00 259.64 ? 117 TYR B OH  1 
ATOM   871  N N   . ALA B 2 118 ? 61.816  75.664  39.079 1.00 252.97 ? 118 ALA B N   1 
ATOM   872  C CA  . ALA B 2 118 ? 61.157  75.384  37.809 1.00 244.94 ? 118 ALA B CA  1 
ATOM   873  C C   . ALA B 2 118 ? 59.622  75.417  37.911 1.00 264.76 ? 118 ALA B C   1 
ATOM   874  O O   . ALA B 2 118 ? 58.965  75.778  36.938 1.00 314.28 ? 118 ALA B O   1 
ATOM   875  C CB  . ALA B 2 118 ? 61.666  74.050  37.293 1.00 246.39 ? 118 ALA B CB  1 
ATOM   876  N N   . TYR B 2 119 ? 59.042  75.051  39.071 1.00 227.14 ? 119 TYR B N   1 
ATOM   877  C CA  . TYR B 2 119 ? 57.604  75.139  39.331 1.00 226.05 ? 119 TYR B CA  1 
ATOM   878  C C   . TYR B 2 119 ? 57.217  76.581  39.677 1.00 250.19 ? 119 TYR B C   1 
ATOM   879  O O   . TYR B 2 119 ? 56.177  77.070  39.218 1.00 297.88 ? 119 TYR B O   1 
ATOM   880  C CB  . TYR B 2 119 ? 57.143  74.181  40.444 1.00 234.57 ? 119 TYR B CB  1 
ATOM   881  C CG  . TYR B 2 119 ? 57.637  72.737  40.346 1.00 261.77 ? 119 TYR B CG  1 
ATOM   882  C CD1 . TYR B 2 119 ? 57.929  72.133  39.119 1.00 267.10 ? 119 TYR B CD1 1 
ATOM   883  C CD2 . TYR B 2 119 ? 57.829  71.967  41.494 1.00 267.19 ? 119 TYR B CD2 1 
ATOM   884  C CE1 . TYR B 2 119 ? 58.390  70.822  39.049 1.00 238.71 ? 119 TYR B CE1 1 
ATOM   885  C CE2 . TYR B 2 119 ? 58.292  70.658  41.436 1.00 294.35 ? 119 TYR B CE2 1 
ATOM   886  C CZ  . TYR B 2 119 ? 58.575  70.078  40.203 1.00 246.02 ? 119 TYR B CZ  1 
ATOM   887  O OH  . TYR B 2 119 ? 59.034  68.792  40.075 1.00 151.37 ? 119 TYR B OH  1 
ATOM   888  N N   . MET B 2 120 ? 58.043  77.276  40.479 1.00 204.01 ? 120 MET B N   1 
ATOM   889  C CA  . MET B 2 120 ? 57.755  78.653  40.882 1.00 183.06 ? 120 MET B CA  1 
ATOM   890  C C   . MET B 2 120 ? 57.666  79.606  39.676 1.00 220.34 ? 120 MET B C   1 
ATOM   891  O O   . MET B 2 120 ? 56.879  80.546  39.721 1.00 231.16 ? 120 MET B O   1 
ATOM   892  C CB  . MET B 2 120 ? 58.817  79.182  41.842 1.00 167.22 ? 120 MET B CB  1 
ATOM   893  C CG  . MET B 2 120 ? 58.876  78.420  43.158 1.00 237.23 ? 120 MET B CG  1 
ATOM   894  S SD  . MET B 2 120 ? 57.569  78.830  44.349 1.00 267.02 ? 120 MET B SD  1 
ATOM   895  C CE  . MET B 2 120 ? 57.777  77.464  45.489 1.00 230.80 ? 120 MET B CE  1 
ATOM   896  N N   . LEU B 2 121 ? 58.437  79.370  38.600 1.00 237.51 ? 121 LEU B N   1 
ATOM   897  C CA  . LEU B 2 121 ? 58.332  80.132  37.359 1.00 227.12 ? 121 LEU B CA  1 
ATOM   898  C C   . LEU B 2 121 ? 56.928  80.076  36.744 1.00 256.77 ? 121 LEU B C   1 
ATOM   899  O O   . LEU B 2 121 ? 56.504  81.059  36.135 1.00 267.50 ? 121 LEU B O   1 
ATOM   900  C CB  . LEU B 2 121 ? 59.365  79.621  36.346 1.00 249.18 ? 121 LEU B CB  1 
ATOM   901  C CG  . LEU B 2 121 ? 60.825  79.915  36.683 1.00 281.70 ? 121 LEU B CG  1 
ATOM   902  C CD1 . LEU B 2 121 ? 61.774  79.156  35.761 1.00 241.54 ? 121 LEU B CD1 1 
ATOM   903  C CD2 . LEU B 2 121 ? 61.128  81.416  36.634 1.00 359.26 ? 121 LEU B CD2 1 
ATOM   904  N N   . GLU B 2 122 ? 56.209  78.947  36.885 1.00 255.68 ? 122 GLU B N   1 
ATOM   905  C CA  . GLU B 2 122 ? 54.851  78.802  36.368 1.00 277.04 ? 122 GLU B CA  1 
ATOM   906  C C   . GLU B 2 122 ? 53.792  79.334  37.338 1.00 236.76 ? 122 GLU B C   1 
ATOM   907  O O   . GLU B 2 122 ? 52.835  79.982  36.901 1.00 257.62 ? 122 GLU B O   1 
ATOM   908  C CB  . GLU B 2 122 ? 54.574  77.334  36.031 1.00 296.12 ? 122 GLU B CB  1 
ATOM   909  C CG  . GLU B 2 122 ? 55.444  76.803  34.894 1.00 364.80 ? 122 GLU B CG  1 
ATOM   910  C CD  . GLU B 2 122 ? 55.328  77.536  33.565 1.00 444.07 ? 122 GLU B CD  1 
ATOM   911  O OE1 . GLU B 2 122 ? 54.306  78.215  33.345 1.00 498.86 ? 122 GLU B OE1 1 
ATOM   912  O OE2 . GLU B 2 122 ? 56.263  77.434  32.748 1.00 467.65 ? 122 GLU B OE2 1 
ATOM   913  N N   . VAL B 2 123 ? 53.950  79.060  38.637 1.00 185.73 ? 123 VAL B N   1 
ATOM   914  C CA  . VAL B 2 123 ? 52.930  79.389  39.630 1.00 211.70 ? 123 VAL B CA  1 
ATOM   915  C C   . VAL B 2 123 ? 52.989  80.873  40.046 1.00 183.17 ? 123 VAL B C   1 
ATOM   916  O O   . VAL B 2 123 ? 51.941  81.443  40.368 1.00 203.45 ? 123 VAL B O   1 
ATOM   917  C CB  . VAL B 2 123 ? 53.016  78.418  40.833 1.00 289.75 ? 123 VAL B CB  1 
ATOM   918  C CG1 . VAL B 2 123 ? 51.967  78.703  41.901 1.00 330.15 ? 123 VAL B CG1 1 
ATOM   919  C CG2 . VAL B 2 123 ? 52.888  76.959  40.405 1.00 289.97 ? 123 VAL B CG2 1 
ATOM   920  N N   . TYR B 2 124 ? 54.180  81.500  40.047 1.00 180.04 ? 124 TYR B N   1 
ATOM   921  C CA  . TYR B 2 124 ? 54.376  82.853  40.573 1.00 201.52 ? 124 TYR B CA  1 
ATOM   922  C C   . TYR B 2 124 ? 55.216  83.764  39.662 1.00 232.65 ? 124 TYR B C   1 
ATOM   923  O O   . TYR B 2 124 ? 54.929  84.960  39.564 1.00 229.09 ? 124 TYR B O   1 
ATOM   924  C CB  . TYR B 2 124 ? 55.056  82.765  41.945 1.00 232.80 ? 124 TYR B CB  1 
ATOM   925  C CG  . TYR B 2 124 ? 54.378  81.910  43.008 1.00 256.72 ? 124 TYR B CG  1 
ATOM   926  C CD1 . TYR B 2 124 ? 53.340  82.402  43.793 1.00 251.45 ? 124 TYR B CD1 1 
ATOM   927  C CD2 . TYR B 2 124 ? 54.780  80.597  43.227 1.00 298.61 ? 124 TYR B CD2 1 
ATOM   928  C CE1 . TYR B 2 124 ? 52.727  81.619  44.763 1.00 258.52 ? 124 TYR B CE1 1 
ATOM   929  C CE2 . TYR B 2 124 ? 54.169  79.801  44.191 1.00 301.31 ? 124 TYR B CE2 1 
ATOM   930  C CZ  . TYR B 2 124 ? 53.137  80.309  44.964 1.00 255.51 ? 124 TYR B CZ  1 
ATOM   931  O OH  . TYR B 2 124 ? 52.544  79.516  45.913 1.00 238.79 ? 124 TYR B OH  1 
ATOM   932  N N   . GLY B 2 125 ? 56.273  83.230  39.016 1.00 277.05 ? 125 GLY B N   1 
ATOM   933  C CA  . GLY B 2 125 ? 57.198  83.996  38.182 1.00 260.45 ? 125 GLY B CA  1 
ATOM   934  C C   . GLY B 2 125 ? 58.005  85.036  38.960 1.00 219.97 ? 125 GLY B C   1 
ATOM   935  O O   . GLY B 2 125 ? 58.095  84.978  40.181 1.00 168.25 ? 125 GLY B O   1 
ATOM   936  N N   . SER B 2 126 ? 58.603  85.982  38.224 1.00 236.42 ? 126 SER B N   1 
ATOM   937  C CA  . SER B 2 126 ? 58.984  87.306  38.727 1.00 276.40 ? 126 SER B CA  1 
ATOM   938  C C   . SER B 2 126 ? 59.795  87.224  40.036 1.00 186.34 ? 126 SER B C   1 
ATOM   939  O O   . SER B 2 126 ? 60.807  86.548  40.071 1.00 109.93 ? 126 SER B O   1 
ATOM   940  C CB  . SER B 2 126 ? 57.716  88.190  38.789 1.00 357.28 ? 126 SER B CB  1 
ATOM   941  O OG  . SER B 2 126 ? 58.009  89.537  39.147 1.00 342.24 ? 126 SER B OG  1 
ATOM   942  N N   . LEU B 2 127 ? 59.366  87.914  41.112 1.00 198.65 ? 127 LEU B N   1 
ATOM   943  C CA  . LEU B 2 127 ? 60.077  87.972  42.386 1.00 154.65 ? 127 LEU B CA  1 
ATOM   944  C C   . LEU B 2 127 ? 60.007  86.653  43.159 1.00 158.85 ? 127 LEU B C   1 
ATOM   945  O O   . LEU B 2 127 ? 61.068  86.178  43.555 1.00 158.15 ? 127 LEU B O   1 
ATOM   946  C CB  . LEU B 2 127 ? 59.540  89.173  43.189 1.00 187.41 ? 127 LEU B CB  1 
ATOM   947  C CG  . LEU B 2 127 ? 59.956  89.259  44.650 1.00 262.64 ? 127 LEU B CG  1 
ATOM   948  C CD1 . LEU B 2 127 ? 61.433  89.522  44.748 1.00 279.02 ? 127 LEU B CD1 1 
ATOM   949  C CD2 . LEU B 2 127 ? 59.197  90.369  45.363 1.00 304.57 ? 127 LEU B CD2 1 
ATOM   950  N N   . PRO B 2 128 ? 58.836  86.024  43.457 1.00 179.11 ? 128 PRO B N   1 
ATOM   951  C CA  . PRO B 2 128 ? 58.833  84.782  44.233 1.00 206.29 ? 128 PRO B CA  1 
ATOM   952  C C   . PRO B 2 128 ? 59.680  83.654  43.656 1.00 158.06 ? 128 PRO B C   1 
ATOM   953  O O   . PRO B 2 128 ? 60.216  82.871  44.440 1.00 254.95 ? 128 PRO B O   1 
ATOM   954  C CB  . PRO B 2 128 ? 57.344  84.389  44.292 1.00 286.58 ? 128 PRO B CB  1 
ATOM   955  C CG  . PRO B 2 128 ? 56.618  85.700  44.143 1.00 294.33 ? 128 PRO B CG  1 
ATOM   956  C CD  . PRO B 2 128 ? 57.460  86.456  43.147 1.00 207.40 ? 128 PRO B CD  1 
ATOM   957  N N   . ALA B 2 129 ? 59.829  83.560  42.328 1.00 137.63 ? 129 ALA B N   1 
ATOM   958  C CA  . ALA B 2 129 ? 60.748  82.595  41.731 1.00 169.08 ? 129 ALA B CA  1 
ATOM   959  C C   . ALA B 2 129 ? 62.211  82.894  42.118 1.00 148.20 ? 129 ALA B C   1 
ATOM   960  O O   . ALA B 2 129 ? 62.946  81.986  42.498 1.00 107.61 ? 129 ALA B O   1 
ATOM   961  C CB  . ALA B 2 129 ? 60.527  82.562  40.235 1.00 232.23 ? 129 ALA B CB  1 
ATOM   962  N N   . PHE B 2 130 ? 62.641  84.162  42.052 1.00 151.51 ? 130 PHE B N   1 
ATOM   963  C CA  . PHE B 2 130 ? 63.975  84.547  42.500 1.00 123.02 ? 130 PHE B CA  1 
ATOM   964  C C   . PHE B 2 130 ? 64.152  84.308  44.002 1.00 137.69 ? 130 PHE B C   1 
ATOM   965  O O   . PHE B 2 130 ? 65.198  83.819  44.414 1.00 201.32 ? 130 PHE B O   1 
ATOM   966  C CB  . PHE B 2 130 ? 64.239  86.022  42.219 1.00 162.59 ? 130 PHE B CB  1 
ATOM   967  C CG  . PHE B 2 130 ? 65.596  86.493  42.679 1.00 172.87 ? 130 PHE B CG  1 
ATOM   968  C CD1 . PHE B 2 130 ? 66.706  86.335  41.865 1.00 183.19 ? 130 PHE B CD1 1 
ATOM   969  C CD2 . PHE B 2 130 ? 65.770  87.087  43.927 1.00 129.46 ? 130 PHE B CD2 1 
ATOM   970  C CE1 . PHE B 2 130 ? 67.961  86.772  42.275 1.00 187.75 ? 130 PHE B CE1 1 
ATOM   971  C CE2 . PHE B 2 130 ? 67.026  87.521  44.336 1.00 150.80 ? 130 PHE B CE2 1 
ATOM   972  C CZ  . PHE B 2 130 ? 68.117  87.363  43.507 1.00 149.59 ? 130 PHE B CZ  1 
ATOM   973  N N   . LEU B 2 131 ? 63.145  84.605  44.836 1.00 135.41 ? 131 LEU B N   1 
ATOM   974  C CA  . LEU B 2 131 ? 63.294  84.357  46.262 1.00 149.89 ? 131 LEU B CA  1 
ATOM   975  C C   . LEU B 2 131 ? 63.403  82.854  46.597 1.00 136.40 ? 131 LEU B C   1 
ATOM   976  O O   . LEU B 2 131 ? 64.117  82.503  47.533 1.00 101.89 ? 131 LEU B O   1 
ATOM   977  C CB  . LEU B 2 131 ? 62.159  85.051  47.015 1.00 172.55 ? 131 LEU B CB  1 
ATOM   978  C CG  . LEU B 2 131 ? 62.218  86.578  47.000 1.00 200.35 ? 131 LEU B CG  1 
ATOM   979  C CD1 . LEU B 2 131 ? 61.080  87.109  47.868 1.00 291.52 ? 131 LEU B CD1 1 
ATOM   980  C CD2 . LEU B 2 131 ? 63.557  87.185  47.465 1.00 142.62 ? 131 LEU B CD2 1 
ATOM   981  N N   . LYS B 2 132 ? 62.775  81.946  45.844 1.00 127.41 ? 132 LYS B N   1 
ATOM   982  C CA  . LYS B 2 132 ? 63.035  80.521  46.008 1.00 139.56 ? 132 LYS B CA  1 
ATOM   983  C C   . LYS B 2 132 ? 64.497  80.194  45.674 1.00 111.87 ? 132 LYS B C   1 
ATOM   984  O O   . LYS B 2 132 ? 65.166  79.498  46.437 1.00 168.21 ? 132 LYS B O   1 
ATOM   985  C CB  . LYS B 2 132 ? 62.092  79.657  45.152 1.00 176.73 ? 132 LYS B CB  1 
ATOM   986  C CG  . LYS B 2 132 ? 61.670  78.344  45.784 1.00 207.02 ? 132 LYS B CG  1 
ATOM   987  C CD  . LYS B 2 132 ? 62.760  77.366  46.195 1.00 264.36 ? 132 LYS B CD  1 
ATOM   988  C CE  . LYS B 2 132 ? 62.102  76.144  46.793 1.00 293.22 ? 132 LYS B CE  1 
ATOM   989  N NZ  . LYS B 2 132 ? 63.032  75.054  47.167 1.00 282.53 ? 132 LYS B NZ  1 
ATOM   990  N N   . LEU B 2 133 ? 65.006  80.657  44.538 1.00 110.93 ? 133 LEU B N   1 
ATOM   991  C CA  . LEU B 2 133 ? 66.386  80.400  44.153 1.00 159.26 ? 133 LEU B CA  1 
ATOM   992  C C   . LEU B 2 133 ? 67.360  80.960  45.192 1.00 112.11 ? 133 LEU B C   1 
ATOM   993  O O   . LEU B 2 133 ? 68.366  80.335  45.517 1.00 198.91 ? 133 LEU B O   1 
ATOM   994  C CB  . LEU B 2 133 ? 66.634  81.042  42.780 1.00 174.53 ? 133 LEU B CB  1 
ATOM   995  C CG  . LEU B 2 133 ? 68.005  80.836  42.156 1.00 144.14 ? 133 LEU B CG  1 
ATOM   996  C CD1 . LEU B 2 133 ? 68.203  79.375  41.852 1.00 115.97 ? 133 LEU B CD1 1 
ATOM   997  C CD2 . LEU B 2 133 ? 68.128  81.651  40.903 1.00 242.72 ? 133 LEU B CD2 1 
ATOM   998  N N   . TRP B 2 134 ? 67.086  82.152  45.698 1.00 115.52 ? 134 TRP B N   1 
ATOM   999  C CA  . TRP B 2 134 ? 67.929  82.826  46.655 1.00 124.05 ? 134 TRP B CA  1 
ATOM   1000 C C   . TRP B 2 134 ? 67.905  82.100  47.994 1.00 156.22 ? 134 TRP B C   1 
ATOM   1001 O O   . TRP B 2 134 ? 68.970  81.859  48.556 1.00 137.17 ? 134 TRP B O   1 
ATOM   1002 C CB  . TRP B 2 134 ? 67.401  84.249  46.773 1.00 143.60 ? 134 TRP B CB  1 
ATOM   1003 C CG  . TRP B 2 134 ? 68.155  85.197  47.647 1.00 135.85 ? 134 TRP B CG  1 
ATOM   1004 C CD1 . TRP B 2 134 ? 67.700  85.699  48.830 1.00 140.87 ? 134 TRP B CD1 1 
ATOM   1005 C CD2 . TRP B 2 134 ? 69.458  85.774  47.399 1.00 111.64 ? 134 TRP B CD2 1 
ATOM   1006 N NE1 . TRP B 2 134 ? 68.636  86.561  49.337 1.00 138.18 ? 134 TRP B NE1 1 
ATOM   1007 C CE2 . TRP B 2 134 ? 69.725  86.639  48.499 1.00 120.39 ? 134 TRP B CE2 1 
ATOM   1008 C CE3 . TRP B 2 134 ? 70.418  85.635  46.376 1.00 111.97 ? 134 TRP B CE3 1 
ATOM   1009 C CZ2 . TRP B 2 134 ? 70.921  87.370  48.595 1.00 140.87 ? 134 TRP B CZ2 1 
ATOM   1010 C CZ3 . TRP B 2 134 ? 71.609  86.348  46.475 1.00 140.86 ? 134 TRP B CZ3 1 
ATOM   1011 C CH2 . TRP B 2 134 ? 71.852  87.207  47.572 1.00 158.27 ? 134 TRP B CH2 1 
ATOM   1012 N N   . ILE B 2 135 ? 66.724  81.715  48.509 1.00 149.47 ? 135 ILE B N   1 
ATOM   1013 C CA  . ILE B 2 135 ? 66.650  80.887  49.705 1.00 142.06 ? 135 ILE B CA  1 
ATOM   1014 C C   . ILE B 2 135 ? 67.412  79.579  49.481 1.00 134.97 ? 135 ILE B C   1 
ATOM   1015 O O   . ILE B 2 135 ? 68.196  79.168  50.328 1.00 143.27 ? 135 ILE B O   1 
ATOM   1016 C CB  . ILE B 2 135 ? 65.192  80.634  50.133 1.00 140.30 ? 135 ILE B CB  1 
ATOM   1017 C CG1 . ILE B 2 135 ? 64.562  81.898  50.695 1.00 199.74 ? 135 ILE B CG1 1 
ATOM   1018 C CG2 . ILE B 2 135 ? 65.079  79.530  51.172 1.00 177.29 ? 135 ILE B CG2 1 
ATOM   1019 C CD1 . ILE B 2 135 ? 63.052  81.790  50.889 1.00 270.89 ? 135 ILE B CD1 1 
ATOM   1020 N N   . GLU B 2 136 ? 67.185  78.888  48.368 1.00 123.26 ? 136 GLU B N   1 
ATOM   1021 C CA  . GLU B 2 136 ? 67.778  77.572  48.178 1.00 118.53 ? 136 GLU B CA  1 
ATOM   1022 C C   . GLU B 2 136 ? 69.303  77.625  48.064 1.00 100.13 ? 136 GLU B C   1 
ATOM   1023 O O   . GLU B 2 136 ? 69.949  76.680  48.495 1.00 143.63 ? 136 GLU B O   1 
ATOM   1024 C CB  . GLU B 2 136 ? 67.176  76.867  46.969 1.00 141.57 ? 136 GLU B CB  1 
ATOM   1025 C CG  . GLU B 2 136 ? 67.631  75.416  46.882 1.00 184.04 ? 136 GLU B CG  1 
ATOM   1026 C CD  . GLU B 2 136 ? 66.711  74.451  46.143 1.00 284.58 ? 136 GLU B CD  1 
ATOM   1027 O OE1 . GLU B 2 136 ? 65.479  74.730  46.051 1.00 347.47 ? 136 GLU B OE1 1 
ATOM   1028 O OE2 . GLU B 2 136 ? 67.233  73.417  45.650 1.00 228.62 ? 136 GLU B OE2 1 
ATOM   1029 N N   . LEU B 2 137 ? 69.891  78.687  47.517 1.00 125.34 ? 137 LEU B N   1 
ATOM   1030 C CA  . LEU B 2 137 ? 71.338  78.809  47.373 1.00 123.97 ? 137 LEU B CA  1 
ATOM   1031 C C   . LEU B 2 137 ? 72.022  79.448  48.573 1.00 113.45 ? 137 LEU B C   1 
ATOM   1032 O O   . LEU B 2 137 ? 73.195  79.141  48.765 1.00 198.91 ? 137 LEU B O   1 
ATOM   1033 C CB  . LEU B 2 137 ? 71.671  79.616  46.114 1.00 160.02 ? 137 LEU B CB  1 
ATOM   1034 C CG  . LEU B 2 137 ? 71.419  78.872  44.804 1.00 152.85 ? 137 LEU B CG  1 
ATOM   1035 C CD1 . LEU B 2 137 ? 71.737  79.754  43.623 1.00 133.19 ? 137 LEU B CD1 1 
ATOM   1036 C CD2 . LEU B 2 137 ? 72.223  77.572  44.715 1.00 177.70 ? 137 LEU B CD2 1 
ATOM   1037 N N   . LEU B 2 138 ? 71.354  80.286  49.381 1.00 101.19 ? 138 LEU B N   1 
ATOM   1038 C CA  . LEU B 2 138 ? 72.016  80.877  50.546 1.00 146.52 ? 138 LEU B CA  1 
ATOM   1039 C C   . LEU B 2 138 ? 71.613  80.227  51.884 1.00 153.72 ? 138 LEU B C   1 
ATOM   1040 O O   . LEU B 2 138 ? 72.351  80.335  52.863 1.00 99.58  ? 138 LEU B O   1 
ATOM   1041 C CB  . LEU B 2 138 ? 71.737  82.377  50.590 1.00 148.35 ? 138 LEU B CB  1 
ATOM   1042 C CG  . LEU B 2 138 ? 72.742  83.218  49.829 1.00 147.37 ? 138 LEU B CG  1 
ATOM   1043 C CD1 . LEU B 2 138 ? 72.569  83.069  48.319 1.00 193.28 ? 138 LEU B CD1 1 
ATOM   1044 C CD2 . LEU B 2 138 ? 72.573  84.663  50.279 1.00 167.36 ? 138 LEU B CD2 1 
ATOM   1045 N N   . ILE B 2 139 ? 70.469  79.538  51.951 1.00 145.30 ? 139 ILE B N   1 
ATOM   1046 C CA  . ILE B 2 139 ? 70.066  78.825  53.157 1.00 129.62 ? 139 ILE B CA  1 
ATOM   1047 C C   . ILE B 2 139 ? 70.083  77.316  52.934 1.00 87.79  ? 139 ILE B C   1 
ATOM   1048 O O   . ILE B 2 139 ? 70.861  76.628  53.578 1.00 123.47 ? 139 ILE B O   1 
ATOM   1049 C CB  . ILE B 2 139 ? 68.693  79.326  53.663 1.00 127.32 ? 139 ILE B CB  1 
ATOM   1050 C CG1 . ILE B 2 139 ? 68.840  80.765  54.155 1.00 126.20 ? 139 ILE B CG1 1 
ATOM   1051 C CG2 . ILE B 2 139 ? 68.120  78.420  54.721 1.00 141.40 ? 139 ILE B CG2 1 
ATOM   1052 C CD1 . ILE B 2 139 ? 67.555  81.399  54.647 1.00 142.76 ? 139 ILE B CD1 1 
ATOM   1053 N N   . ILE B 2 140 ? 69.218  76.791  52.087 1.00 63.71  ? 140 ILE B N   1 
ATOM   1054 C CA  . ILE B 2 140 ? 68.976  75.371  52.125 1.00 92.37  ? 140 ILE B CA  1 
ATOM   1055 C C   . ILE B 2 140 ? 70.241  74.588  51.696 1.00 84.00  ? 140 ILE B C   1 
ATOM   1056 O O   . ILE B 2 140 ? 70.753  73.817  52.495 1.00 109.66 ? 140 ILE B O   1 
ATOM   1057 C CB  . ILE B 2 140 ? 67.670  75.009  51.385 1.00 100.54 ? 140 ILE B CB  1 
ATOM   1058 C CG1 . ILE B 2 140 ? 66.473  75.733  52.011 1.00 87.27  ? 140 ILE B CG1 1 
ATOM   1059 C CG2 . ILE B 2 140 ? 67.411  73.481  51.334 1.00 101.62 ? 140 ILE B CG2 1 
ATOM   1060 C CD1 . ILE B 2 140 ? 65.249  75.605  51.051 1.00 168.57 ? 140 ILE B CD1 1 
ATOM   1061 N N   . ARG B 2 141 ? 70.731  74.721  50.477 1.00 79.88  ? 141 ARG B N   1 
ATOM   1062 C CA  . ARG B 2 141 ? 71.809  73.873  50.000 1.00 117.66 ? 141 ARG B CA  1 
ATOM   1063 C C   . ARG B 2 141 ? 73.112  74.096  50.774 1.00 103.34 ? 141 ARG B C   1 
ATOM   1064 O O   . ARG B 2 141 ? 73.871  73.140  50.897 1.00 111.86 ? 141 ARG B O   1 
ATOM   1065 C CB  . ARG B 2 141 ? 72.046  74.085  48.492 1.00 236.52 ? 141 ARG B CB  1 
ATOM   1066 C CG  . ARG B 2 141 ? 70.981  73.454  47.613 1.00 242.89 ? 141 ARG B CG  1 
ATOM   1067 C CD  . ARG B 2 141 ? 71.177  73.616  46.102 1.00 188.09 ? 141 ARG B CD  1 
ATOM   1068 N NE  . ARG B 2 141 ? 70.050  73.001  45.409 1.00 222.86 ? 141 ARG B NE  1 
ATOM   1069 C CZ  . ARG B 2 141 ? 69.897  71.697  45.170 1.00 340.91 ? 141 ARG B CZ  1 
ATOM   1070 N NH1 . ARG B 2 141 ? 68.685  71.208  44.918 1.00 374.12 ? 141 ARG B NH1 1 
ATOM   1071 N NH2 . ARG B 2 141 ? 70.943  70.883  45.214 1.00 351.34 ? 141 ARG B NH2 1 
ATOM   1072 N N   . PRO B 2 142 ? 73.493  75.300  51.268 1.00 90.26  ? 142 PRO B N   1 
ATOM   1073 C CA  . PRO B 2 142 ? 74.603  75.454  52.200 1.00 121.35 ? 142 PRO B CA  1 
ATOM   1074 C C   . PRO B 2 142 ? 74.441  74.742  53.548 1.00 146.63 ? 142 PRO B C   1 
ATOM   1075 O O   . PRO B 2 142 ? 75.310  73.967  53.962 1.00 74.94  ? 142 PRO B O   1 
ATOM   1076 C CB  . PRO B 2 142 ? 74.670  76.965  52.444 1.00 96.02  ? 142 PRO B CB  1 
ATOM   1077 C CG  . PRO B 2 142 ? 74.124  77.528  51.232 1.00 144.48 ? 142 PRO B CG  1 
ATOM   1078 C CD  . PRO B 2 142 ? 72.981  76.597  50.903 1.00 112.49 ? 142 PRO B CD  1 
ATOM   1079 N N   . SER B 2 143 ? 73.328  74.983  54.243 1.00 108.76 ? 143 SER B N   1 
ATOM   1080 C CA  . SER B 2 143 ? 73.199  74.475  55.584 1.00 68.69  ? 143 SER B CA  1 
ATOM   1081 C C   . SER B 2 143 ? 73.118  72.940  55.592 1.00 89.90  ? 143 SER B C   1 
ATOM   1082 O O   . SER B 2 143 ? 73.748  72.329  56.450 1.00 140.90 ? 143 SER B O   1 
ATOM   1083 C CB  . SER B 2 143 ? 71.985  75.078  56.243 1.00 90.90  ? 143 SER B CB  1 
ATOM   1084 O OG  . SER B 2 143 ? 70.792  74.805  55.517 1.00 130.18 ? 143 SER B OG  1 
ATOM   1085 N N   . SER B 2 144 ? 72.359  72.280  54.700 1.00 66.23  ? 144 SER B N   1 
ATOM   1086 C CA  . SER B 2 144 ? 72.375  70.834  54.668 1.00 86.35  ? 144 SER B CA  1 
ATOM   1087 C C   . SER B 2 144 ? 73.727  70.240  54.250 1.00 64.81  ? 144 SER B C   1 
ATOM   1088 O O   . SER B 2 144 ? 73.978  69.069  54.484 1.00 91.54  ? 144 SER B O   1 
ATOM   1089 C CB  . SER B 2 144 ? 71.294  70.275  53.766 1.00 128.69 ? 144 SER B CB  1 
ATOM   1090 O OG  . SER B 2 144 ? 71.592  70.492  52.392 1.00 192.55 ? 144 SER B OG  1 
ATOM   1091 N N   . GLN B 2 145 ? 74.609  70.974  53.574 1.00 83.30  ? 145 GLN B N   1 
ATOM   1092 C CA  . GLN B 2 145 ? 75.952  70.477  53.298 1.00 140.02 ? 145 GLN B CA  1 
ATOM   1093 C C   . GLN B 2 145 ? 76.800  70.608  54.535 1.00 94.94  ? 145 GLN B C   1 
ATOM   1094 O O   . GLN B 2 145 ? 77.517  69.677  54.887 1.00 103.90 ? 145 GLN B O   1 
ATOM   1095 C CB  . GLN B 2 145 ? 76.659  71.206  52.156 1.00 135.51 ? 145 GLN B CB  1 
ATOM   1096 C CG  . GLN B 2 145 ? 76.145  70.779  50.796 1.00 166.63 ? 145 GLN B CG  1 
ATOM   1097 C CD  . GLN B 2 145 ? 76.678  71.701  49.736 1.00 190.73 ? 145 GLN B CD  1 
ATOM   1098 O OE1 . GLN B 2 145 ? 77.893  71.899  49.636 1.00 252.45 ? 145 GLN B OE1 1 
ATOM   1099 N NE2 . GLN B 2 145 ? 75.783  72.278  48.943 1.00 222.59 ? 145 GLN B NE2 1 
ATOM   1100 N N   . TYR B 2 146 ? 76.729  71.743  55.198 1.00 96.49  ? 146 TYR B N   1 
ATOM   1101 C CA  . TYR B 2 146 ? 77.548  71.928  56.385 1.00 101.70 ? 146 TYR B CA  1 
ATOM   1102 C C   . TYR B 2 146 ? 77.163  70.892  57.432 1.00 87.27  ? 146 TYR B C   1 
ATOM   1103 O O   . TYR B 2 146 ? 78.070  70.366  58.037 1.00 54.10  ? 146 TYR B O   1 
ATOM   1104 C CB  . TYR B 2 146 ? 77.362  73.391  56.859 1.00 126.79 ? 146 TYR B CB  1 
ATOM   1105 C CG  . TYR B 2 146 ? 78.111  73.600  58.150 1.00 120.39 ? 146 TYR B CG  1 
ATOM   1106 C CD1 . TYR B 2 146 ? 79.497  73.749  58.136 1.00 94.49  ? 146 TYR B CD1 1 
ATOM   1107 C CD2 . TYR B 2 146 ? 77.418  73.556  59.364 1.00 122.65 ? 146 TYR B CD2 1 
ATOM   1108 C CE1 . TYR B 2 146 ? 80.192  73.886  59.327 1.00 107.15 ? 146 TYR B CE1 1 
ATOM   1109 C CE2 . TYR B 2 146 ? 78.109  73.703  60.549 1.00 141.83 ? 146 TYR B CE2 1 
ATOM   1110 C CZ  . TYR B 2 146 ? 79.494  73.857  60.532 1.00 125.91 ? 146 TYR B CZ  1 
ATOM   1111 O OH  . TYR B 2 146 ? 80.123  73.978  61.736 1.00 145.25 ? 146 TYR B OH  1 
ATOM   1112 N N   . ILE B 2 147 ? 75.866  70.636  57.682 1.00 83.72  ? 147 ILE B N   1 
ATOM   1113 C CA  . ILE B 2 147 ? 75.420  69.640  58.623 1.00 81.40  ? 147 ILE B CA  1 
ATOM   1114 C C   . ILE B 2 147 ? 76.005  68.258  58.315 1.00 70.19  ? 147 ILE B C   1 
ATOM   1115 O O   . ILE B 2 147 ? 76.516  67.601  59.241 1.00 65.41  ? 147 ILE B O   1 
ATOM   1116 C CB  . ILE B 2 147 ? 73.892  69.609  58.705 1.00 85.55  ? 147 ILE B CB  1 
ATOM   1117 C CG1 . ILE B 2 147 ? 73.403  70.820  59.507 1.00 72.22  ? 147 ILE B CG1 1 
ATOM   1118 C CG2 . ILE B 2 147 ? 73.344  68.246  59.242 1.00 103.37 ? 147 ILE B CG2 1 
ATOM   1119 C CD1 . ILE B 2 147 ? 71.936  71.027  59.074 1.00 104.33 ? 147 ILE B CD1 1 
ATOM   1120 N N   . VAL B 2 148 ? 75.992  67.838  57.063 1.00 49.89  ? 148 VAL B N   1 
ATOM   1121 C CA  . VAL B 2 148 ? 76.546  66.546  56.744 1.00 68.79  ? 148 VAL B CA  1 
ATOM   1122 C C   . VAL B 2 148 ? 78.086  66.577  56.798 1.00 83.41  ? 148 VAL B C   1 
ATOM   1123 O O   . VAL B 2 148 ? 78.742  65.602  57.156 1.00 98.99  ? 148 VAL B O   1 
ATOM   1124 C CB  . VAL B 2 148 ? 76.000  65.998  55.422 1.00 94.55  ? 148 VAL B CB  1 
ATOM   1125 C CG1 . VAL B 2 148 ? 76.558  64.652  55.096 1.00 110.73 ? 148 VAL B CG1 1 
ATOM   1126 C CG2 . VAL B 2 148 ? 74.511  65.761  55.545 1.00 168.48 ? 148 VAL B CG2 1 
ATOM   1127 N N   . ALA B 2 149 ? 78.714  67.686  56.470 1.00 89.50  ? 149 ALA B N   1 
ATOM   1128 C CA  . ALA B 2 149 ? 80.164  67.820  56.595 1.00 93.51  ? 149 ALA B CA  1 
ATOM   1129 C C   . ALA B 2 149 ? 80.622  67.804  58.017 1.00 64.50  ? 149 ALA B C   1 
ATOM   1130 O O   . ALA B 2 149 ? 81.712  67.342  58.307 1.00 105.17 ? 149 ALA B O   1 
ATOM   1131 C CB  . ALA B 2 149 ? 80.603  69.110  55.943 1.00 148.77 ? 149 ALA B CB  1 
ATOM   1132 N N   . LEU B 2 150 ? 79.801  68.301  58.933 1.00 91.23  ? 150 LEU B N   1 
ATOM   1133 C CA  . LEU B 2 150 ? 80.138  68.332  60.356 1.00 91.01  ? 150 LEU B CA  1 
ATOM   1134 C C   . LEU B 2 150 ? 79.863  66.993  61.030 1.00 82.03  ? 150 LEU B C   1 
ATOM   1135 O O   . LEU B 2 150 ? 80.663  66.617  61.897 1.00 72.94  ? 150 LEU B O   1 
ATOM   1136 C CB  . LEU B 2 150 ? 79.334  69.468  61.003 1.00 78.07  ? 150 LEU B CB  1 
ATOM   1137 C CG  . LEU B 2 150 ? 79.679  69.763  62.431 1.00 90.08  ? 150 LEU B CG  1 
ATOM   1138 C CD1 . LEU B 2 150 ? 81.110  70.240  62.523 1.00 103.49 ? 150 LEU B CD1 1 
ATOM   1139 C CD2 . LEU B 2 150 ? 78.730  70.804  62.970 1.00 162.21 ? 150 LEU B CD2 1 
ATOM   1140 N N   . VAL B 2 151 ? 78.770  66.276  60.678 1.00 77.66  ? 151 VAL B N   1 
ATOM   1141 C CA  . VAL B 2 151 ? 78.609  64.941  61.204 1.00 108.68 ? 151 VAL B CA  1 
ATOM   1142 C C   . VAL B 2 151 ? 79.807  64.084  60.742 1.00 75.69  ? 151 VAL B C   1 
ATOM   1143 O O   . VAL B 2 151 ? 80.328  63.270  61.543 1.00 112.73 ? 151 VAL B O   1 
ATOM   1144 C CB  . VAL B 2 151 ? 77.247  64.277  60.933 1.00 93.87  ? 151 VAL B CB  1 
ATOM   1145 C CG1 . VAL B 2 151 ? 77.102  63.782  59.532 1.00 127.62 ? 151 VAL B CG1 1 
ATOM   1146 C CG2 . VAL B 2 151 ? 77.046  63.034  61.813 1.00 128.94 ? 151 VAL B CG2 1 
ATOM   1147 N N   . PHE B 2 152 ? 80.240  64.213  59.508 1.00 80.24  ? 152 PHE B N   1 
ATOM   1148 C CA  . PHE B 2 152 ? 81.426  63.519  59.054 1.00 101.43 ? 152 PHE B CA  1 
ATOM   1149 C C   . PHE B 2 152 ? 82.572  63.794  60.003 1.00 77.25  ? 152 PHE B C   1 
ATOM   1150 O O   . PHE B 2 152 ? 83.244  62.843  60.430 1.00 98.21  ? 152 PHE B O   1 
ATOM   1151 C CB  . PHE B 2 152 ? 81.803  63.921  57.619 1.00 118.38 ? 152 PHE B CB  1 
ATOM   1152 C CG  . PHE B 2 152 ? 83.186  63.449  57.250 1.00 108.60 ? 152 PHE B CG  1 
ATOM   1153 C CD1 . PHE B 2 152 ? 83.400  62.104  56.986 1.00 98.09  ? 152 PHE B CD1 1 
ATOM   1154 C CD2 . PHE B 2 152 ? 84.256  64.326  57.201 1.00 120.56 ? 152 PHE B CD2 1 
ATOM   1155 C CE1 . PHE B 2 152 ? 84.656  61.640  56.651 1.00 129.82 ? 152 PHE B CE1 1 
ATOM   1156 C CE2 . PHE B 2 152 ? 85.513  63.881  56.872 1.00 134.81 ? 152 PHE B CE2 1 
ATOM   1157 C CZ  . PHE B 2 152 ? 85.709  62.541  56.598 1.00 160.40 ? 152 PHE B CZ  1 
ATOM   1158 N N   . ALA B 2 153 ? 82.808  65.074  60.305 1.00 79.64  ? 153 ALA B N   1 
ATOM   1159 C CA  . ALA B 2 153 ? 83.960  65.480  61.086 1.00 119.91 ? 153 ALA B CA  1 
ATOM   1160 C C   . ALA B 2 153 ? 83.872  64.899  62.517 1.00 112.38 ? 153 ALA B C   1 
ATOM   1161 O O   . ALA B 2 153 ? 84.837  64.336  63.043 1.00 61.92  ? 153 ALA B O   1 
ATOM   1162 C CB  . ALA B 2 153 ? 84.107  66.992  61.007 1.00 102.73 ? 153 ALA B CB  1 
ATOM   1163 N N   . THR B 2 154 ? 82.733  65.003  63.181 1.00 87.79  ? 154 THR B N   1 
ATOM   1164 C CA  . THR B 2 154 ? 82.626  64.468  64.529 1.00 90.75  ? 154 THR B CA  1 
ATOM   1165 C C   . THR B 2 154 ? 82.828  62.977  64.538 1.00 72.80  ? 154 THR B C   1 
ATOM   1166 O O   . THR B 2 154 ? 83.561  62.499  65.407 1.00 124.03 ? 154 THR B O   1 
ATOM   1167 C CB  . THR B 2 154 ? 81.317  64.840  65.236 1.00 97.40  ? 154 THR B CB  1 
ATOM   1168 O OG1 . THR B 2 154 ? 80.234  64.355  64.458 1.00 112.43 ? 154 THR B OG1 1 
ATOM   1169 C CG2 . THR B 2 154 ? 81.217  66.353  65.423 1.00 129.07 ? 154 THR B CG2 1 
ATOM   1170 N N   . TYR B 2 155 ? 82.217  62.230  63.637 1.00 63.06  ? 155 TYR B N   1 
ATOM   1171 C CA  . TYR B 2 155 ? 82.424  60.791  63.659 1.00 86.06  ? 155 TYR B CA  1 
ATOM   1172 C C   . TYR B 2 155 ? 83.856  60.379  63.301 1.00 80.04  ? 155 TYR B C   1 
ATOM   1173 O O   . TYR B 2 155 ? 84.357  59.405  63.851 1.00 102.83 ? 155 TYR B O   1 
ATOM   1174 C CB  . TYR B 2 155 ? 81.530  60.076  62.666 1.00 125.36 ? 155 TYR B CB  1 
ATOM   1175 C CG  . TYR B 2 155 ? 80.179  59.722  63.207 1.00 84.12  ? 155 TYR B CG  1 
ATOM   1176 C CD1 . TYR B 2 155 ? 79.302  60.703  63.573 1.00 92.90  ? 155 TYR B CD1 1 
ATOM   1177 C CD2 . TYR B 2 155 ? 79.774  58.419  63.269 1.00 100.73 ? 155 TYR B CD2 1 
ATOM   1178 C CE1 . TYR B 2 155 ? 78.033  60.393  64.030 1.00 134.76 ? 155 TYR B CE1 1 
ATOM   1179 C CE2 . TYR B 2 155 ? 78.516  58.095  63.735 1.00 127.35 ? 155 TYR B CE2 1 
ATOM   1180 C CZ  . TYR B 2 155 ? 77.631  59.080  64.108 1.00 108.67 ? 155 TYR B CZ  1 
ATOM   1181 O OH  . TYR B 2 155 ? 76.385  58.777  64.574 1.00 147.13 ? 155 TYR B OH  1 
ATOM   1182 N N   . LEU B 2 156 ? 84.524  61.084  62.389 1.00 94.20  ? 156 LEU B N   1 
ATOM   1183 C CA  . LEU B 2 156 ? 85.892  60.747  62.034 1.00 122.17 ? 156 LEU B CA  1 
ATOM   1184 C C   . LEU B 2 156 ? 86.810  60.996  63.219 1.00 110.04 ? 156 LEU B C   1 
ATOM   1185 O O   . LEU B 2 156 ? 87.753  60.224  63.418 1.00 175.75 ? 156 LEU B O   1 
ATOM   1186 C CB  . LEU B 2 156 ? 86.342  61.610  60.857 1.00 149.91 ? 156 LEU B CB  1 
ATOM   1187 C CG  . LEU B 2 156 ? 87.729  61.285  60.329 1.00 166.14 ? 156 LEU B CG  1 
ATOM   1188 C CD1 . LEU B 2 156 ? 87.687  59.971  59.547 1.00 239.97 ? 156 LEU B CD1 1 
ATOM   1189 C CD2 . LEU B 2 156 ? 88.256  62.448  59.519 1.00 162.07 ? 156 LEU B CD2 1 
ATOM   1190 N N   . LEU B 2 157 ? 86.537  62.052  64.003 1.00 74.13  ? 157 LEU B N   1 
ATOM   1191 C CA  . LEU B 2 157 ? 87.340  62.347  65.171 1.00 101.68 ? 157 LEU B CA  1 
ATOM   1192 C C   . LEU B 2 157 ? 86.958  61.549  66.422 1.00 103.63 ? 157 LEU B C   1 
ATOM   1193 O O   . LEU B 2 157 ? 87.858  61.316  67.233 1.00 123.51 ? 157 LEU B O   1 
ATOM   1194 C CB  . LEU B 2 157 ? 87.214  63.841  65.416 1.00 100.99 ? 157 LEU B CB  1 
ATOM   1195 C CG  . LEU B 2 157 ? 88.017  64.686  64.438 1.00 114.32 ? 157 LEU B CG  1 
ATOM   1196 C CD1 . LEU B 2 157 ? 87.663  66.237  64.647 1.00 64.86  ? 157 LEU B CD1 1 
ATOM   1197 C CD2 . LEU B 2 157 ? 89.550  64.215  64.514 1.00 73.29  ? 157 LEU B CD2 1 
ATOM   1198 N N   . LYS B 2 158 ? 85.703  61.135  66.616 1.00 93.66  ? 158 LYS B N   1 
ATOM   1199 C CA  . LYS B 2 158 ? 85.235  60.645  67.912 1.00 92.54  ? 158 LYS B CA  1 
ATOM   1200 C C   . LYS B 2 158 ? 86.096  59.515  68.476 1.00 105.30 ? 158 LYS B C   1 
ATOM   1201 O O   . LYS B 2 158 ? 86.296  59.508  69.677 1.00 156.35 ? 158 LYS B O   1 
ATOM   1202 C CB  . LYS B 2 158 ? 83.784  60.152  67.867 1.00 121.34 ? 158 LYS B CB  1 
ATOM   1203 C CG  . LYS B 2 158 ? 83.078  59.943  69.215 1.00 117.87 ? 158 LYS B CG  1 
ATOM   1204 C CD  . LYS B 2 158 ? 82.909  61.279  69.980 1.00 130.83 ? 158 LYS B CD  1 
ATOM   1205 C CE  . LYS B 2 158 ? 81.950  61.214  71.153 1.00 123.65 ? 158 LYS B CE  1 
ATOM   1206 N NZ  . LYS B 2 158 ? 82.582  60.516  72.276 1.00 163.71 ? 158 LYS B NZ  1 
ATOM   1207 N N   . PRO B 2 159 ? 86.624  58.514  67.742 1.00 83.88  ? 159 PRO B N   1 
ATOM   1208 C CA  . PRO B 2 159 ? 87.510  57.528  68.347 1.00 117.60 ? 159 PRO B CA  1 
ATOM   1209 C C   . PRO B 2 159 ? 88.775  58.074  69.022 1.00 138.10 ? 159 PRO B C   1 
ATOM   1210 O O   . PRO B 2 159 ? 89.343  57.355  69.841 1.00 223.21 ? 159 PRO B O   1 
ATOM   1211 C CB  . PRO B 2 159 ? 87.880  56.618  67.161 1.00 175.21 ? 159 PRO B CB  1 
ATOM   1212 C CG  . PRO B 2 159 ? 86.641  56.731  66.317 1.00 183.96 ? 159 PRO B CG  1 
ATOM   1213 C CD  . PRO B 2 159 ? 86.355  58.218  66.353 1.00 101.25 ? 159 PRO B CD  1 
ATOM   1214 N N   . LEU B 2 160 ? 89.223  59.304  68.710 1.00 94.46  ? 160 LEU B N   1 
ATOM   1215 C CA  . LEU B 2 160 ? 90.298  59.934  69.488 1.00 143.55 ? 160 LEU B CA  1 
ATOM   1216 C C   . LEU B 2 160 ? 89.831  60.587  70.806 1.00 129.21 ? 160 LEU B C   1 
ATOM   1217 O O   . LEU B 2 160 ? 90.680  60.978  71.601 1.00 126.62 ? 160 LEU B O   1 
ATOM   1218 C CB  . LEU B 2 160 ? 90.973  61.014  68.651 1.00 134.44 ? 160 LEU B CB  1 
ATOM   1219 C CG  . LEU B 2 160 ? 91.939  60.584  67.580 1.00 190.41 ? 160 LEU B CG  1 
ATOM   1220 C CD1 . LEU B 2 160 ? 91.282  59.638  66.593 1.00 256.83 ? 160 LEU B CD1 1 
ATOM   1221 C CD2 . LEU B 2 160 ? 92.443  61.860  66.910 1.00 185.33 ? 160 LEU B CD2 1 
ATOM   1222 N N   . PHE B 2 161 ? 88.513  60.700  71.030 1.00 97.77  ? 161 PHE B N   1 
ATOM   1223 C CA  . PHE B 2 161 ? 87.893  61.363  72.161 1.00 125.61 ? 161 PHE B CA  1 
ATOM   1224 C C   . PHE B 2 161 ? 86.682  60.545  72.636 1.00 125.26 ? 161 PHE B C   1 
ATOM   1225 O O   . PHE B 2 161 ? 85.521  60.934  72.457 1.00 125.25 ? 161 PHE B O   1 
ATOM   1226 C CB  . PHE B 2 161 ? 87.529  62.795  71.744 1.00 142.04 ? 161 PHE B CB  1 
ATOM   1227 C CG  . PHE B 2 161 ? 88.719  63.669  71.418 1.00 105.33 ? 161 PHE B CG  1 
ATOM   1228 C CD1 . PHE B 2 161 ? 89.524  64.203  72.388 1.00 154.14 ? 161 PHE B CD1 1 
ATOM   1229 C CD2 . PHE B 2 161 ? 89.048  63.931  70.138 1.00 130.48 ? 161 PHE B CD2 1 
ATOM   1230 C CE1 . PHE B 2 161 ? 90.607  64.996  72.086 1.00 169.91 ? 161 PHE B CE1 1 
ATOM   1231 C CE2 . PHE B 2 161 ? 90.129  64.722  69.827 1.00 153.39 ? 161 PHE B CE2 1 
ATOM   1232 C CZ  . PHE B 2 161 ? 90.903  65.253  70.800 1.00 156.80 ? 161 PHE B CZ  1 
ATOM   1233 N N   . PRO B 2 162 ? 86.942  59.371  73.254 1.00 122.70 ? 162 PRO B N   1 
ATOM   1234 C CA  . PRO B 2 162 ? 85.895  58.383  73.524 1.00 136.52 ? 162 PRO B CA  1 
ATOM   1235 C C   . PRO B 2 162 ? 84.873  58.830  74.561 1.00 135.68 ? 162 PRO B C   1 
ATOM   1236 O O   . PRO B 2 162 ? 83.705  58.484  74.414 1.00 192.74 ? 162 PRO B O   1 
ATOM   1237 C CB  . PRO B 2 162 ? 86.689  57.151  73.999 1.00 187.61 ? 162 PRO B CB  1 
ATOM   1238 C CG  . PRO B 2 162 ? 88.001  57.719  74.530 1.00 199.48 ? 162 PRO B CG  1 
ATOM   1239 C CD  . PRO B 2 162 ? 88.282  58.947  73.694 1.00 130.25 ? 162 PRO B CD  1 
ATOM   1240 N N   . THR B 2 163 ? 85.286  59.617  75.579 1.00 106.44 ? 163 THR B N   1 
ATOM   1241 C CA  . THR B 2 163 ? 84.406  60.005  76.667 1.00 169.82 ? 163 THR B CA  1 
ATOM   1242 C C   . THR B 2 163 ? 84.042  61.488  76.555 1.00 146.85 ? 163 THR B C   1 
ATOM   1243 O O   . THR B 2 163 ? 82.850  61.836  76.549 1.00 183.72 ? 163 THR B O   1 
ATOM   1244 C CB  . THR B 2 163 ? 85.042  59.669  78.027 1.00 261.47 ? 163 THR B CB  1 
ATOM   1245 O OG1 . THR B 2 163 ? 85.374  58.277  78.057 1.00 247.64 ? 163 THR B OG1 1 
ATOM   1246 C CG2 . THR B 2 163 ? 84.133  59.989  79.199 1.00 334.39 ? 163 THR B CG2 1 
ATOM   1247 N N   . CYS B 2 164 ? 85.081  62.322  76.508 1.00 120.65 ? 164 CYS B N   1 
ATOM   1248 C CA  . CYS B 2 164 ? 84.951  63.778  76.549 1.00 145.04 ? 164 CYS B CA  1 
ATOM   1249 C C   . CYS B 2 164 ? 84.587  64.310  75.178 1.00 104.50 ? 164 CYS B C   1 
ATOM   1250 O O   . CYS B 2 164 ? 84.926  63.664  74.195 1.00 165.93 ? 164 CYS B O   1 
ATOM   1251 C CB  . CYS B 2 164 ? 86.217  64.455  77.077 1.00 183.03 ? 164 CYS B CB  1 
ATOM   1252 S SG  . CYS B 2 164 ? 87.704  64.213  76.083 1.00 245.77 ? 164 CYS B SG  1 
ATOM   1253 N N   . PRO B 2 165 ? 83.870  65.452  75.034 1.00 107.40 ? 165 PRO B N   1 
ATOM   1254 C CA  . PRO B 2 165 ? 83.352  65.861  73.737 1.00 122.45 ? 165 PRO B CA  1 
ATOM   1255 C C   . PRO B 2 165 ? 84.487  66.355  72.842 1.00 146.83 ? 165 PRO B C   1 
ATOM   1256 O O   . PRO B 2 165 ? 85.444  66.933  73.340 1.00 101.12 ? 165 PRO B O   1 
ATOM   1257 C CB  . PRO B 2 165 ? 82.348  66.962  74.016 1.00 160.02 ? 165 PRO B CB  1 
ATOM   1258 C CG  . PRO B 2 165 ? 82.865  67.564  75.296 1.00 177.44 ? 165 PRO B CG  1 
ATOM   1259 C CD  . PRO B 2 165 ? 83.449  66.394  76.075 1.00 193.86 ? 165 PRO B CD  1 
ATOM   1260 N N   . VAL B 2 166 ? 84.362  66.074  71.517 1.00 197.37 ? 166 VAL B N   1 
ATOM   1261 C CA  . VAL B 2 166 ? 85.409  66.328  70.512 1.00 109.94 ? 166 VAL B CA  1 
ATOM   1262 C C   . VAL B 2 166 ? 85.515  67.839  70.342 1.00 120.74 ? 166 VAL B C   1 
ATOM   1263 O O   . VAL B 2 166 ? 84.458  68.523  70.330 1.00 93.09  ? 166 VAL B O   1 
ATOM   1264 C CB  . VAL B 2 166 ? 85.013  65.659  69.187 1.00 137.92 ? 166 VAL B CB  1 
ATOM   1265 C CG1 . VAL B 2 166 ? 83.757  66.301  68.568 1.00 170.53 ? 166 VAL B CG1 1 
ATOM   1266 C CG2 . VAL B 2 166 ? 86.133  65.710  68.191 1.00 114.29 ? 166 VAL B CG2 1 
ATOM   1267 N N   . PRO B 2 167 ? 86.759  68.408  70.270 1.00 129.11 ? 167 PRO B N   1 
ATOM   1268 C CA  . PRO B 2 167 ? 86.950  69.881  70.350 1.00 136.04 ? 167 PRO B CA  1 
ATOM   1269 C C   . PRO B 2 167 ? 86.391  70.607  69.147 1.00 106.97 ? 167 PRO B C   1 
ATOM   1270 O O   . PRO B 2 167 ? 86.771  70.268  68.037 1.00 122.42 ? 167 PRO B O   1 
ATOM   1271 C CB  . PRO B 2 167 ? 88.452  70.108  70.406 1.00 122.63 ? 167 PRO B CB  1 
ATOM   1272 C CG  . PRO B 2 167 ? 89.035  68.739  69.981 1.00 128.74 ? 167 PRO B CG  1 
ATOM   1273 C CD  . PRO B 2 167 ? 88.016  67.641  70.243 1.00 69.48  ? 167 PRO B CD  1 
ATOM   1274 N N   . GLU B 2 168 ? 85.457  71.557  69.351 1.00 150.90 ? 168 GLU B N   1 
ATOM   1275 C CA  . GLU B 2 168 ? 84.685  72.154  68.248 1.00 198.93 ? 168 GLU B CA  1 
ATOM   1276 C C   . GLU B 2 168 ? 85.591  72.869  67.232 1.00 144.16 ? 168 GLU B C   1 
ATOM   1277 O O   . GLU B 2 168 ? 85.379  72.797  66.017 1.00 107.08 ? 168 GLU B O   1 
ATOM   1278 C CB  . GLU B 2 168 ? 83.591  73.108  68.760 1.00 184.20 ? 168 GLU B CB  1 
ATOM   1279 C CG  . GLU B 2 168 ? 82.486  72.413  69.558 1.00 266.81 ? 168 GLU B CG  1 
ATOM   1280 C CD  . GLU B 2 168 ? 81.674  71.310  68.882 1.00 286.37 ? 168 GLU B CD  1 
ATOM   1281 O OE1 . GLU B 2 168 ? 81.786  71.131  67.658 1.00 279.60 ? 168 GLU B OE1 1 
ATOM   1282 O OE2 . GLU B 2 168 ? 80.917  70.617  69.592 1.00 327.16 ? 168 GLU B OE2 1 
ATOM   1283 N N   . GLU B 2 169 ? 86.621  73.539  67.714 1.00 137.33 ? 169 GLU B N   1 
ATOM   1284 C CA  . GLU B 2 169 ? 87.575  74.177  66.824 1.00 166.06 ? 169 GLU B CA  1 
ATOM   1285 C C   . GLU B 2 169 ? 88.233  73.178  65.857 1.00 90.92  ? 169 GLU B C   1 
ATOM   1286 O O   . GLU B 2 169 ? 88.750  73.617  64.844 1.00 96.81  ? 169 GLU B O   1 
ATOM   1287 C CB  . GLU B 2 169 ? 88.623  74.955  67.652 1.00 253.83 ? 169 GLU B CB  1 
ATOM   1288 C CG  . GLU B 2 169 ? 89.356  74.154  68.735 1.00 271.63 ? 169 GLU B CG  1 
ATOM   1289 C CD  . GLU B 2 169 ? 88.823  74.298  70.150 1.00 330.65 ? 169 GLU B CD  1 
ATOM   1290 O OE1 . GLU B 2 169 ? 87.588  74.335  70.314 1.00 349.71 ? 169 GLU B OE1 1 
ATOM   1291 O OE2 . GLU B 2 169 ? 89.645  74.371  71.082 1.00 395.75 ? 169 GLU B OE2 1 
ATOM   1292 N N   . ALA B 2 170 ? 88.327  71.882  66.185 1.00 96.21  ? 170 ALA B N   1 
ATOM   1293 C CA  . ALA B 2 170 ? 88.904  70.860  65.313 1.00 126.63 ? 170 ALA B CA  1 
ATOM   1294 C C   . ALA B 2 170 ? 87.811  70.256  64.451 1.00 90.26  ? 170 ALA B C   1 
ATOM   1295 O O   . ALA B 2 170 ? 88.036  69.997  63.274 1.00 119.07 ? 170 ALA B O   1 
ATOM   1296 C CB  . ALA B 2 170 ? 89.648  69.760  66.064 1.00 106.55 ? 170 ALA B CB  1 
ATOM   1297 N N   . ALA B 2 171 ? 86.643  70.034  65.007 1.00 99.46  ? 171 ALA B N   1 
ATOM   1298 C CA  . ALA B 2 171 ? 85.523  69.541  64.237 1.00 125.42 ? 171 ALA B CA  1 
ATOM   1299 C C   . ALA B 2 171 ? 85.261  70.494  63.079 1.00 113.88 ? 171 ALA B C   1 
ATOM   1300 O O   . ALA B 2 171 ? 85.005  70.008  61.956 1.00 195.74 ? 171 ALA B O   1 
ATOM   1301 C CB  . ALA B 2 171 ? 84.308  69.396  65.139 1.00 175.71 ? 171 ALA B CB  1 
ATOM   1302 N N   . LYS B 2 172 ? 85.300  71.817  63.301 1.00 63.74  ? 172 LYS B N   1 
ATOM   1303 C CA  . LYS B 2 172 ? 85.031  72.724  62.201 1.00 99.41  ? 172 LYS B CA  1 
ATOM   1304 C C   . LYS B 2 172 ? 86.118  72.755  61.110 1.00 93.53  ? 172 LYS B C   1 
ATOM   1305 O O   . LYS B 2 172 ? 85.800  72.817  59.943 1.00 100.11 ? 172 LYS B O   1 
ATOM   1306 C CB  . LYS B 2 172 ? 84.744  74.105  62.739 1.00 107.58 ? 172 LYS B CB  1 
ATOM   1307 C CG  . LYS B 2 172 ? 83.387  74.201  63.374 1.00 99.71  ? 172 LYS B CG  1 
ATOM   1308 C CD  . LYS B 2 172 ? 83.202  75.607  63.937 1.00 141.47 ? 172 LYS B CD  1 
ATOM   1309 C CE  . LYS B 2 172 ? 81.830  75.719  64.558 1.00 201.95 ? 172 LYS B CE  1 
ATOM   1310 N NZ  . LYS B 2 172 ? 81.566  77.116  64.975 1.00 228.32 ? 172 LYS B NZ  1 
ATOM   1311 N N   . LEU B 2 173 ? 87.372  72.658  61.432 1.00 75.87  ? 173 LEU B N   1 
ATOM   1312 C CA  . LEU B 2 173 ? 88.393  72.516  60.419 1.00 93.42  ? 173 LEU B CA  1 
ATOM   1313 C C   . LEU B 2 173 ? 88.252  71.208  59.651 1.00 89.88  ? 173 LEU B C   1 
ATOM   1314 O O   . LEU B 2 173 ? 88.358  71.220  58.429 1.00 167.21 ? 173 LEU B O   1 
ATOM   1315 C CB  . LEU B 2 173 ? 89.830  72.522  60.979 1.00 93.17  ? 173 LEU B CB  1 
ATOM   1316 C CG  . LEU B 2 173 ? 90.276  73.808  61.642 1.00 121.17 ? 173 LEU B CG  1 
ATOM   1317 C CD1 . LEU B 2 173 ? 91.804  73.602  61.787 1.00 105.51 ? 173 LEU B CD1 1 
ATOM   1318 C CD2 . LEU B 2 173 ? 89.806  75.154  60.948 1.00 103.15 ? 173 LEU B CD2 1 
ATOM   1319 N N   . VAL B 2 174 ? 88.067  70.063  60.288 1.00 62.04  ? 174 VAL B N   1 
ATOM   1320 C CA  . VAL B 2 174 ? 87.933  68.849  59.522 1.00 72.88  ? 174 VAL B CA  1 
ATOM   1321 C C   . VAL B 2 174 ? 86.636  68.846  58.720 1.00 71.93  ? 174 VAL B C   1 
ATOM   1322 O O   . VAL B 2 174 ? 86.639  68.207  57.672 1.00 120.11 ? 174 VAL B O   1 
ATOM   1323 C CB  . VAL B 2 174 ? 88.077  67.612  60.405 1.00 95.55  ? 174 VAL B CB  1 
ATOM   1324 C CG1 . VAL B 2 174 ? 87.640  66.316  59.667 1.00 95.04  ? 174 VAL B CG1 1 
ATOM   1325 C CG2 . VAL B 2 174 ? 89.531  67.620  60.850 1.00 84.50  ? 174 VAL B CG2 1 
ATOM   1326 N N   . ALA B 2 175 ? 85.566  69.534  59.126 1.00 72.51  ? 175 ALA B N   1 
ATOM   1327 C CA  . ALA B 2 175 ? 84.396  69.697  58.262 1.00 110.94 ? 175 ALA B CA  1 
ATOM   1328 C C   . ALA B 2 175 ? 84.783  70.442  56.997 1.00 74.37  ? 175 ALA B C   1 
ATOM   1329 O O   . ALA B 2 175 ? 84.408  70.028  55.894 1.00 78.06  ? 175 ALA B O   1 
ATOM   1330 C CB  . ALA B 2 175 ? 83.231  70.370  58.964 1.00 107.60 ? 175 ALA B CB  1 
ATOM   1331 N N   . CYS B 2 176 ? 85.529  71.531  57.157 1.00 79.60  ? 176 CYS B N   1 
ATOM   1332 C CA  . CYS B 2 176 ? 85.977  72.346  56.038 1.00 113.37 ? 176 CYS B CA  1 
ATOM   1333 C C   . CYS B 2 176 ? 86.914  71.591  55.098 1.00 60.52  ? 176 CYS B C   1 
ATOM   1334 O O   . CYS B 2 176 ? 86.770  71.719  53.882 1.00 92.19  ? 176 CYS B O   1 
ATOM   1335 C CB  . CYS B 2 176 ? 86.519  73.668  56.575 1.00 100.98 ? 176 CYS B CB  1 
ATOM   1336 S SG  . CYS B 2 176 ? 85.125  74.501  57.408 1.00 125.94 ? 176 CYS B SG  1 
ATOM   1337 N N   . LEU B 2 177 ? 87.852  70.856  55.628 1.00 64.97  ? 177 LEU B N   1 
ATOM   1338 C CA  . LEU B 2 177 ? 88.757  70.079  54.803 1.00 109.32 ? 177 LEU B CA  1 
ATOM   1339 C C   . LEU B 2 177 ? 87.997  69.090  53.926 1.00 82.01  ? 177 LEU B C   1 
ATOM   1340 O O   . LEU B 2 177 ? 88.435  68.904  52.784 1.00 206.99 ? 177 LEU B O   1 
ATOM   1341 C CB  . LEU B 2 177 ? 89.778  69.343  55.677 1.00 146.01 ? 177 LEU B CB  1 
ATOM   1342 C CG  . LEU B 2 177 ? 90.826  70.249  56.306 1.00 149.21 ? 177 LEU B CG  1 
ATOM   1343 C CD1 . LEU B 2 177 ? 91.514  69.621  57.481 1.00 174.71 ? 177 LEU B CD1 1 
ATOM   1344 C CD2 . LEU B 2 177 ? 91.867  70.594  55.303 1.00 129.21 ? 177 LEU B CD2 1 
ATOM   1345 N N   . CYS B 2 178 ? 86.905  68.514  54.400 1.00 69.09  ? 178 CYS B N   1 
ATOM   1346 C CA  . CYS B 2 178 ? 86.070  67.632  53.616 1.00 96.46  ? 178 CYS B CA  1 
ATOM   1347 C C   . CYS B 2 178 ? 85.352  68.390  52.486 1.00 108.68 ? 178 CYS B C   1 
ATOM   1348 O O   . CYS B 2 178 ? 85.422  67.956  51.331 1.00 171.55 ? 178 CYS B O   1 
ATOM   1349 C CB  . CYS B 2 178 ? 85.092  66.936  54.552 1.00 143.70 ? 178 CYS B CB  1 
ATOM   1350 S SG  . CYS B 2 178 ? 84.100  65.701  53.710 1.00 201.59 ? 178 CYS B SG  1 
ATOM   1351 N N   . VAL B 2 179 ? 84.684  69.509  52.783 1.00 69.29  ? 179 VAL B N   1 
ATOM   1352 C CA  . VAL B 2 179 ? 84.000  70.262  51.748 1.00 93.30  ? 179 VAL B CA  1 
ATOM   1353 C C   . VAL B 2 179 ? 84.957  70.818  50.683 1.00 93.24  ? 179 VAL B C   1 
ATOM   1354 O O   . VAL B 2 179 ? 84.615  70.833  49.507 1.00 122.10 ? 179 VAL B O   1 
ATOM   1355 C CB  . VAL B 2 179 ? 83.136  71.387  52.371 1.00 136.99 ? 179 VAL B CB  1 
ATOM   1356 C CG1 . VAL B 2 179 ? 82.521  72.389  51.416 1.00 114.39 ? 179 VAL B CG1 1 
ATOM   1357 C CG2 . VAL B 2 179 ? 82.005  70.765  53.151 1.00 206.21 ? 179 VAL B CG2 1 
ATOM   1358 N N   . LEU B 2 180 ? 86.132  71.302  51.040 1.00 99.95  ? 180 LEU B N   1 
ATOM   1359 C CA  . LEU B 2 180 ? 87.076  71.802  50.032 1.00 68.21  ? 180 LEU B CA  1 
ATOM   1360 C C   . LEU B 2 180 ? 87.624  70.630  49.238 1.00 63.15  ? 180 LEU B C   1 
ATOM   1361 O O   . LEU B 2 180 ? 87.671  70.753  48.018 1.00 156.77 ? 180 LEU B O   1 
ATOM   1362 C CB  . LEU B 2 180 ? 88.305  72.482  50.650 1.00 83.04  ? 180 LEU B CB  1 
ATOM   1363 C CG  . LEU B 2 180 ? 88.072  73.772  51.415 1.00 113.62 ? 180 LEU B CG  1 
ATOM   1364 C CD1 . LEU B 2 180 ? 89.444  74.459  51.623 1.00 161.55 ? 180 LEU B CD1 1 
ATOM   1365 C CD2 . LEU B 2 180 ? 87.057  74.599  50.703 1.00 66.81  ? 180 LEU B CD2 1 
ATOM   1366 N N   . LEU B 2 181 ? 88.060  69.529  49.840 1.00 57.72  ? 181 LEU B N   1 
ATOM   1367 C CA  . LEU B 2 181 ? 88.566  68.408  49.075 1.00 84.06  ? 181 LEU B CA  1 
ATOM   1368 C C   . LEU B 2 181 ? 87.520  67.897  48.055 1.00 101.79 ? 181 LEU B C   1 
ATOM   1369 O O   . LEU B 2 181 ? 87.888  67.646  46.889 1.00 158.12 ? 181 LEU B O   1 
ATOM   1370 C CB  . LEU B 2 181 ? 88.969  67.262  50.001 1.00 111.52 ? 181 LEU B CB  1 
ATOM   1371 C CG  . LEU B 2 181 ? 89.452  66.008  49.290 1.00 94.32  ? 181 LEU B CG  1 
ATOM   1372 C CD1 . LEU B 2 181 ? 90.765  66.423  48.711 1.00 156.02 ? 181 LEU B CD1 1 
ATOM   1373 C CD2 . LEU B 2 181 ? 89.628  64.794  50.147 1.00 135.01 ? 181 LEU B CD2 1 
ATOM   1374 N N   . LEU B 2 182 ? 86.254  67.761  48.436 1.00 85.37  ? 182 LEU B N   1 
ATOM   1375 C CA  . LEU B 2 182 ? 85.252  67.316  47.502 1.00 124.74 ? 182 LEU B CA  1 
ATOM   1376 C C   . LEU B 2 182 ? 84.840  68.408  46.498 1.00 123.67 ? 182 LEU B C   1 
ATOM   1377 O O   . LEU B 2 182 ? 84.301  68.074  45.429 1.00 203.48 ? 182 LEU B O   1 
ATOM   1378 C CB  . LEU B 2 182 ? 84.075  66.777  48.330 1.00 116.16 ? 182 LEU B CB  1 
ATOM   1379 C CG  . LEU B 2 182 ? 84.390  65.413  48.930 1.00 143.17 ? 182 LEU B CG  1 
ATOM   1380 C CD1 . LEU B 2 182 ? 83.251  64.994  49.843 1.00 235.23 ? 182 LEU B CD1 1 
ATOM   1381 C CD2 . LEU B 2 182 ? 84.616  64.349  47.874 1.00 147.60 ? 182 LEU B CD2 1 
ATOM   1382 N N   . THR B 2 183 ? 85.068  69.684  46.789 1.00 92.79  ? 183 THR B N   1 
ATOM   1383 C CA  . THR B 2 183 ? 84.901  70.720  45.799 1.00 97.44  ? 183 THR B CA  1 
ATOM   1384 C C   . THR B 2 183 ? 86.000  70.572  44.775 1.00 97.95  ? 183 THR B C   1 
ATOM   1385 O O   . THR B 2 183 ? 85.732  70.694  43.577 1.00 193.95 ? 183 THR B O   1 
ATOM   1386 C CB  . THR B 2 183 ? 84.910  72.131  46.429 1.00 129.71 ? 183 THR B CB  1 
ATOM   1387 O OG1 . THR B 2 183 ? 83.822  72.268  47.349 1.00 85.07  ? 183 THR B OG1 1 
ATOM   1388 C CG2 . THR B 2 183 ? 84.790  73.253  45.411 1.00 124.92 ? 183 THR B CG2 1 
ATOM   1389 N N   . ALA B 2 184 ? 87.241  70.368  45.188 1.00 91.84  ? 184 ALA B N   1 
ATOM   1390 C CA  . ALA B 2 184 ? 88.348  70.198  44.252 1.00 125.07 ? 184 ALA B CA  1 
ATOM   1391 C C   . ALA B 2 184 ? 88.101  68.979  43.358 1.00 118.18 ? 184 ALA B C   1 
ATOM   1392 O O   . ALA B 2 184 ? 88.299  69.073  42.134 1.00 163.81 ? 184 ALA B O   1 
ATOM   1393 C CB  . ALA B 2 184 ? 89.676  70.095  44.976 1.00 141.02 ? 184 ALA B CB  1 
ATOM   1394 N N   . VAL B 2 185 ? 87.688  67.833  43.917 1.00 87.62  ? 185 VAL B N   1 
ATOM   1395 C CA  . VAL B 2 185 ? 87.470  66.644  43.106 1.00 99.93  ? 185 VAL B CA  1 
ATOM   1396 C C   . VAL B 2 185 ? 86.350  66.856  42.087 1.00 111.13 ? 185 VAL B C   1 
ATOM   1397 O O   . VAL B 2 185 ? 86.518  66.433  40.934 1.00 235.45 ? 185 VAL B O   1 
ATOM   1398 C CB  . VAL B 2 185 ? 87.278  65.412  43.990 1.00 161.47 ? 185 VAL B CB  1 
ATOM   1399 C CG1 . VAL B 2 185 ? 86.618  64.216  43.277 1.00 184.38 ? 185 VAL B CG1 1 
ATOM   1400 C CG2 . VAL B 2 185 ? 88.651  65.056  44.585 1.00 170.18 ? 185 VAL B CG2 1 
ATOM   1401 N N   . ASN B 2 186 ? 85.255  67.524  42.441 1.00 123.88 ? 186 ASN B N   1 
ATOM   1402 C CA  . ASN B 2 186 ? 84.193  67.833  41.483 1.00 129.27 ? 186 ASN B CA  1 
ATOM   1403 C C   . ASN B 2 186 ? 84.632  68.857  40.439 1.00 112.50 ? 186 ASN B C   1 
ATOM   1404 O O   . ASN B 2 186 ? 84.077  68.826  39.337 1.00 172.88 ? 186 ASN B O   1 
ATOM   1405 C CB  . ASN B 2 186 ? 82.897  68.241  42.195 1.00 160.65 ? 186 ASN B CB  1 
ATOM   1406 C CG  . ASN B 2 186 ? 82.142  67.028  42.686 1.00 187.01 ? 186 ASN B CG  1 
ATOM   1407 O OD1 . ASN B 2 186 ? 81.304  66.498  41.966 1.00 136.76 ? 186 ASN B OD1 1 
ATOM   1408 N ND2 . ASN B 2 186 ? 82.446  66.555  43.884 1.00 231.56 ? 186 ASN B ND2 1 
ATOM   1409 N N   . CYS B 2 187 ? 85.593  69.759  40.743 1.00 108.99 ? 187 CYS B N   1 
ATOM   1410 C CA  . CYS B 2 187 ? 86.159  70.664  39.741 1.00 161.97 ? 187 CYS B CA  1 
ATOM   1411 C C   . CYS B 2 187 ? 87.115  69.950  38.790 1.00 142.13 ? 187 CYS B C   1 
ATOM   1412 O O   . CYS B 2 187 ? 87.100  70.231  37.601 1.00 123.00 ? 187 CYS B O   1 
ATOM   1413 C CB  . CYS B 2 187 ? 86.842  71.854  40.392 1.00 133.32 ? 187 CYS B CB  1 
ATOM   1414 S SG  . CYS B 2 187 ? 85.655  72.952  41.211 1.00 194.41 ? 187 CYS B SG  1 
ATOM   1415 N N   . TYR B 2 188 ? 87.943  69.036  39.282 1.00 135.54 ? 188 TYR B N   1 
ATOM   1416 C CA  . TYR B 2 188 ? 88.922  68.347  38.449 1.00 136.16 ? 188 TYR B CA  1 
ATOM   1417 C C   . TYR B 2 188 ? 88.288  67.333  37.519 1.00 120.59 ? 188 TYR B C   1 
ATOM   1418 O O   . TYR B 2 188 ? 88.790  67.216  36.385 1.00 242.76 ? 188 TYR B O   1 
ATOM   1419 C CB  . TYR B 2 188 ? 89.987  67.624  39.277 1.00 194.19 ? 188 TYR B CB  1 
ATOM   1420 C CG  . TYR B 2 188 ? 91.164  68.492  39.719 1.00 272.98 ? 188 TYR B CG  1 
ATOM   1421 C CD1 . TYR B 2 188 ? 91.099  69.890  39.863 1.00 230.34 ? 188 TYR B CD1 1 
ATOM   1422 C CD2 . TYR B 2 188 ? 92.406  67.878  39.946 1.00 294.39 ? 188 TYR B CD2 1 
ATOM   1423 C CE1 . TYR B 2 188 ? 92.213  70.620  40.260 1.00 200.52 ? 188 TYR B CE1 1 
ATOM   1424 C CE2 . TYR B 2 188 ? 93.520  68.608  40.333 1.00 312.00 ? 188 TYR B CE2 1 
ATOM   1425 C CZ  . TYR B 2 188 ? 93.423  69.984  40.493 1.00 277.83 ? 188 TYR B CZ  1 
ATOM   1426 O OH  . TYR B 2 188 ? 94.508  70.729  40.867 1.00 215.94 ? 188 TYR B OH  1 
ATOM   1427 N N   . SER B 2 189 ? 87.231  66.617  37.932 1.00 120.82 ? 189 SER B N   1 
ATOM   1428 C CA  . SER B 2 189 ? 86.722  65.548  37.080 1.00 196.83 ? 189 SER B CA  1 
ATOM   1429 C C   . SER B 2 189 ? 85.346  65.003  37.445 1.00 154.24 ? 189 SER B C   1 
ATOM   1430 O O   . SER B 2 189 ? 85.232  64.295  38.458 1.00 235.91 ? 189 SER B O   1 
ATOM   1431 C CB  . SER B 2 189 ? 87.709  64.394  37.089 1.00 215.29 ? 189 SER B CB  1 
ATOM   1432 O OG  . SER B 2 189 ? 87.267  63.382  36.192 1.00 203.68 ? 189 SER B OG  1 
ATOM   1433 N N   . VAL B 2 190 ? 84.328  65.251  36.595 1.00 145.22 ? 190 VAL B N   1 
ATOM   1434 C CA  . VAL B 2 190 ? 83.059  64.519  36.703 1.00 211.14 ? 190 VAL B CA  1 
ATOM   1435 C C   . VAL B 2 190 ? 83.259  63.000  36.502 1.00 174.32 ? 190 VAL B C   1 
ATOM   1436 O O   . VAL B 2 190 ? 82.548  62.193  37.122 1.00 174.18 ? 190 VAL B O   1 
ATOM   1437 C CB  . VAL B 2 190 ? 81.949  65.119  35.805 1.00 226.48 ? 190 VAL B CB  1 
ATOM   1438 C CG1 . VAL B 2 190 ? 80.759  64.187  35.580 1.00 230.75 ? 190 VAL B CG1 1 
ATOM   1439 C CG2 . VAL B 2 190 ? 81.426  66.421  36.389 1.00 214.90 ? 190 VAL B CG2 1 
ATOM   1440 N N   . LYS B 2 191 ? 84.237  62.602  35.674 1.00 191.73 ? 191 LYS B N   1 
ATOM   1441 C CA  . LYS B 2 191 ? 84.579  61.199  35.460 1.00 272.43 ? 191 LYS B CA  1 
ATOM   1442 C C   . LYS B 2 191 ? 85.113  60.525  36.737 1.00 247.51 ? 191 LYS B C   1 
ATOM   1443 O O   . LYS B 2 191 ? 84.940  59.312  36.885 1.00 257.76 ? 191 LYS B O   1 
ATOM   1444 C CB  . LYS B 2 191 ? 85.566  61.089  34.286 1.00 357.62 ? 191 LYS B CB  1 
ATOM   1445 C CG  . LYS B 2 191 ? 85.825  59.675  33.781 1.00 406.87 ? 191 LYS B CG  1 
ATOM   1446 C CD  . LYS B 2 191 ? 86.647  59.626  32.513 1.00 428.26 ? 191 LYS B CD  1 
ATOM   1447 C CE  . LYS B 2 191 ? 86.872  58.221  31.990 1.00 427.92 ? 191 LYS B CE  1 
ATOM   1448 N NZ  . LYS B 2 191 ? 87.831  57.449  32.819 1.00 401.78 ? 191 LYS B NZ  1 
ATOM   1449 N N   . ALA B 2 192 ? 85.747  61.279  37.658 1.00 222.12 ? 192 ALA B N   1 
ATOM   1450 C CA  . ALA B 2 192 ? 86.134  60.784  38.981 1.00 247.89 ? 192 ALA B CA  1 
ATOM   1451 C C   . ALA B 2 192 ? 85.005  60.924  40.011 1.00 188.15 ? 192 ALA B C   1 
ATOM   1452 O O   . ALA B 2 192 ? 84.688  59.967  40.700 1.00 122.30 ? 192 ALA B O   1 
ATOM   1453 C CB  . ALA B 2 192 ? 87.383  61.497  39.450 1.00 272.14 ? 192 ALA B CB  1 
ATOM   1454 N N   . ALA B 2 193 ? 84.397  62.109  40.130 1.00 161.63 ? 193 ALA B N   1 
ATOM   1455 C CA  . ALA B 2 193 ? 83.380  62.367  41.149 1.00 163.01 ? 193 ALA B CA  1 
ATOM   1456 C C   . ALA B 2 193 ? 82.092  61.510  41.019 1.00 135.33 ? 193 ALA B C   1 
ATOM   1457 O O   . ALA B 2 193 ? 81.478  61.199  42.042 1.00 163.50 ? 193 ALA B O   1 
ATOM   1458 C CB  . ALA B 2 193 ? 83.077  63.827  41.145 1.00 147.69 ? 193 ALA B CB  1 
ATOM   1459 N N   . THR B 2 194 ? 81.726  61.081  39.811 1.00 128.36 ? 194 THR B N   1 
ATOM   1460 C CA  . THR B 2 194 ? 80.735  60.030  39.621 1.00 184.47 ? 194 THR B CA  1 
ATOM   1461 C C   . THR B 2 194 ? 81.133  58.691  40.277 1.00 173.16 ? 194 THR B C   1 
ATOM   1462 O O   . THR B 2 194 ? 80.294  58.095  40.952 1.00 151.80 ? 194 THR B O   1 
ATOM   1463 C CB  . THR B 2 194 ? 80.423  59.795  38.132 1.00 259.15 ? 194 THR B CB  1 
ATOM   1464 O OG1 . THR B 2 194 ? 81.615  59.708  37.352 1.00 236.24 ? 194 THR B OG1 1 
ATOM   1465 C CG2 . THR B 2 194 ? 79.571  60.886  37.531 1.00 262.31 ? 194 THR B CG2 1 
ATOM   1466 N N   . ARG B 2 195 ? 82.388  58.222  40.129 1.00 136.91 ? 195 ARG B N   1 
ATOM   1467 C CA  . ARG B 2 195 ? 82.842  56.968  40.741 1.00 234.95 ? 195 ARG B CA  1 
ATOM   1468 C C   . ARG B 2 195 ? 82.856  57.052  42.278 1.00 229.45 ? 195 ARG B C   1 
ATOM   1469 O O   . ARG B 2 195 ? 82.551  56.087  42.963 1.00 174.33 ? 195 ARG B O   1 
ATOM   1470 C CB  . ARG B 2 195 ? 84.224  56.570  40.205 1.00 291.52 ? 195 ARG B CB  1 
ATOM   1471 C CG  . ARG B 2 195 ? 84.269  56.333  38.705 1.00 325.39 ? 195 ARG B CG  1 
ATOM   1472 C CD  . ARG B 2 195 ? 85.629  55.837  38.250 1.00 318.43 ? 195 ARG B CD  1 
ATOM   1473 N NE  . ARG B 2 195 ? 85.792  54.399  38.465 1.00 316.20 ? 195 ARG B NE  1 
ATOM   1474 C CZ  . ARG B 2 195 ? 86.941  53.731  38.364 1.00 333.63 ? 195 ARG B CZ  1 
ATOM   1475 N NH1 . ARG B 2 195 ? 86.951  52.409  38.439 1.00 310.17 ? 195 ARG B NH1 1 
ATOM   1476 N NH2 . ARG B 2 195 ? 88.080  54.379  38.181 1.00 353.36 ? 195 ARG B NH2 1 
ATOM   1477 N N   . VAL B 2 196 ? 83.196  58.229  42.822 1.00 203.26 ? 196 VAL B N   1 
ATOM   1478 C CA  . VAL B 2 196 ? 83.120  58.519  44.254 1.00 174.03 ? 196 VAL B CA  1 
ATOM   1479 C C   . VAL B 2 196 ? 81.668  58.487  44.755 1.00 190.34 ? 196 VAL B C   1 
ATOM   1480 O O   . VAL B 2 196 ? 81.445  58.154  45.913 1.00 185.18 ? 196 VAL B O   1 
ATOM   1481 C CB  . VAL B 2 196 ? 83.834  59.856  44.577 1.00 164.01 ? 196 VAL B CB  1 
ATOM   1482 C CG1 . VAL B 2 196 ? 83.747  60.293  46.034 1.00 144.13 ? 196 VAL B CG1 1 
ATOM   1483 C CG2 . VAL B 2 196 ? 85.315  59.792  44.206 1.00 206.51 ? 196 VAL B CG2 1 
ATOM   1484 N N   . GLN B 2 197 ? 80.672  58.825  43.917 1.00 244.49 ? 197 GLN B N   1 
ATOM   1485 C CA  . GLN B 2 197 ? 79.262  58.678  44.288 1.00 226.41 ? 197 GLN B CA  1 
ATOM   1486 C C   . GLN B 2 197 ? 78.774  57.231  44.147 1.00 189.33 ? 197 GLN B C   1 
ATOM   1487 O O   . GLN B 2 197 ? 78.013  56.753  44.986 1.00 196.94 ? 197 GLN B O   1 
ATOM   1488 C CB  . GLN B 2 197 ? 78.386  59.633  43.463 1.00 228.39 ? 197 GLN B CB  1 
ATOM   1489 C CG  . GLN B 2 197 ? 76.924  59.698  43.907 1.00 252.52 ? 197 GLN B CG  1 
ATOM   1490 C CD  . GLN B 2 197 ? 76.727  59.963  45.382 1.00 245.73 ? 197 GLN B CD  1 
ATOM   1491 O OE1 . GLN B 2 197 ? 75.904  59.347  46.055 1.00 282.82 ? 197 GLN B OE1 1 
ATOM   1492 N NE2 . GLN B 2 197 ? 77.491  60.897  45.917 1.00 226.00 ? 197 GLN B NE2 1 
ATOM   1493 N N   . ASP B 2 198 ? 79.189  56.530  43.086 1.00 204.42 ? 198 ASP B N   1 
ATOM   1494 C CA  . ASP B 2 198 ? 78.782  55.157  42.814 1.00 253.94 ? 198 ASP B CA  1 
ATOM   1495 C C   . ASP B 2 198 ? 79.170  54.204  43.952 1.00 239.08 ? 198 ASP B C   1 
ATOM   1496 O O   . ASP B 2 198 ? 78.376  53.324  44.305 1.00 265.84 ? 198 ASP B O   1 
ATOM   1497 C CB  . ASP B 2 198 ? 79.371  54.682  41.475 1.00 305.43 ? 198 ASP B CB  1 
ATOM   1498 C CG  . ASP B 2 198 ? 78.863  55.394  40.223 1.00 336.10 ? 198 ASP B CG  1 
ATOM   1499 O OD1 . ASP B 2 198 ? 77.774  56.012  40.279 1.00 372.58 ? 198 ASP B OD1 1 
ATOM   1500 O OD2 . ASP B 2 198 ? 79.558  55.324  39.185 1.00 318.37 ? 198 ASP B OD2 1 
ATOM   1501 N N   . ALA B 2 199 ? 80.380  54.376  44.516 1.00 188.62 ? 199 ALA B N   1 
ATOM   1502 C CA  . ALA B 2 199 ? 80.921  53.513  45.563 1.00 227.34 ? 199 ALA B CA  1 
ATOM   1503 C C   . ALA B 2 199 ? 80.227  53.680  46.928 1.00 209.63 ? 199 ALA B C   1 
ATOM   1504 O O   . ALA B 2 199 ? 79.660  52.734  47.485 1.00 162.72 ? 199 ALA B O   1 
ATOM   1505 C CB  . ALA B 2 199 ? 82.405  53.786  45.678 1.00 213.12 ? 199 ALA B CB  1 
ATOM   1506 N N   . PHE B 2 200 ? 80.273  54.886  47.510 1.00 170.62 ? 200 PHE B N   1 
ATOM   1507 C CA  . PHE B 2 200 ? 79.945  55.082  48.925 1.00 152.08 ? 200 PHE B CA  1 
ATOM   1508 C C   . PHE B 2 200 ? 78.438  55.000  49.245 1.00 146.93 ? 200 PHE B C   1 
ATOM   1509 O O   . PHE B 2 200 ? 78.072  54.914  50.413 1.00 147.91 ? 200 PHE B O   1 
ATOM   1510 C CB  . PHE B 2 200 ? 80.606  56.363  49.433 1.00 145.24 ? 200 PHE B CB  1 
ATOM   1511 C CG  . PHE B 2 200 ? 82.114  56.368  49.367 1.00 149.84 ? 200 PHE B CG  1 
ATOM   1512 C CD1 . PHE B 2 200 ? 82.867  55.263  49.775 1.00 249.29 ? 200 PHE B CD1 1 
ATOM   1513 C CD2 . PHE B 2 200 ? 82.792  57.479  48.905 1.00 160.70 ? 200 PHE B CD2 1 
ATOM   1514 C CE1 . PHE B 2 200 ? 84.256  55.261  49.702 1.00 287.13 ? 200 PHE B CE1 1 
ATOM   1515 C CE2 . PHE B 2 200 ? 84.184  57.469  48.829 1.00 240.70 ? 200 PHE B CE2 1 
ATOM   1516 C CZ  . PHE B 2 200 ? 84.915  56.372  49.232 1.00 277.11 ? 200 PHE B CZ  1 
ATOM   1517 N N   . ALA B 2 201 ? 77.545  54.977  48.255 1.00 192.63 ? 201 ALA B N   1 
ATOM   1518 C CA  . ALA B 2 201 ? 76.147  54.610  48.476 1.00 182.97 ? 201 ALA B CA  1 
ATOM   1519 C C   . ALA B 2 201 ? 76.002  53.215  49.116 1.00 196.84 ? 201 ALA B C   1 
ATOM   1520 O O   . ALA B 2 201 ? 74.992  52.947  49.781 1.00 180.80 ? 201 ALA B O   1 
ATOM   1521 C CB  . ALA B 2 201 ? 75.386  54.712  47.155 1.00 219.09 ? 201 ALA B CB  1 
ATOM   1522 N N   . ALA B 2 202 ? 76.994  52.316  48.931 1.00 186.23 ? 202 ALA B N   1 
ATOM   1523 C CA  . ALA B 2 202 ? 77.040  51.021  49.600 1.00 233.92 ? 202 ALA B CA  1 
ATOM   1524 C C   . ALA B 2 202 ? 77.298  51.167  51.101 1.00 206.73 ? 202 ALA B C   1 
ATOM   1525 O O   . ALA B 2 202 ? 76.669  50.464  51.895 1.00 251.21 ? 202 ALA B O   1 
ATOM   1526 C CB  . ALA B 2 202 ? 78.081  50.138  48.933 1.00 283.66 ? 202 ALA B CB  1 
ATOM   1527 N N   . ALA B 2 203 ? 78.220  52.062  51.499 1.00 219.99 ? 203 ALA B N   1 
ATOM   1528 C CA  . ALA B 2 203 ? 78.569  52.293  52.901 1.00 212.85 ? 203 ALA B CA  1 
ATOM   1529 C C   . ALA B 2 203 ? 77.390  52.835  53.725 1.00 128.78 ? 203 ALA B C   1 
ATOM   1530 O O   . ALA B 2 203 ? 77.197  52.429  54.868 1.00 150.16 ? 203 ALA B O   1 
ATOM   1531 C CB  . ALA B 2 203 ? 79.766  53.203  52.963 1.00 183.49 ? 203 ALA B CB  1 
ATOM   1532 N N   . LYS B 2 204 ? 76.586  53.721  53.143 1.00 120.75 ? 204 LYS B N   1 
ATOM   1533 C CA  . LYS B 2 204 ? 75.349  54.235  53.727 1.00 163.21 ? 204 LYS B CA  1 
ATOM   1534 C C   . LYS B 2 204 ? 74.452  53.120  54.267 1.00 158.01 ? 204 LYS B C   1 
ATOM   1535 O O   . LYS B 2 204 ? 74.064  53.170  55.434 1.00 117.94 ? 204 LYS B O   1 
ATOM   1536 C CB  . LYS B 2 204 ? 74.613  55.066  52.668 1.00 232.85 ? 204 LYS B CB  1 
ATOM   1537 C CG  . LYS B 2 204 ? 73.405  55.863  53.133 1.00 196.64 ? 204 LYS B CG  1 
ATOM   1538 C CD  . LYS B 2 204 ? 72.558  56.358  51.957 1.00 254.87 ? 204 LYS B CD  1 
ATOM   1539 C CE  . LYS B 2 204 ? 73.266  57.292  50.991 1.00 297.98 ? 204 LYS B CE  1 
ATOM   1540 N NZ  . LYS B 2 204 ? 72.337  57.858  49.985 1.00 315.55 ? 204 LYS B NZ  1 
ATOM   1541 N N   . LEU B 2 205 ? 74.128  52.125  53.422 1.00 173.36 ? 205 LEU B N   1 
ATOM   1542 C CA  . LEU B 2 205 ? 73.252  51.034  53.809 1.00 191.60 ? 205 LEU B CA  1 
ATOM   1543 C C   . LEU B 2 205 ? 74.002  49.983  54.633 1.00 141.87 ? 205 LEU B C   1 
ATOM   1544 O O   . LEU B 2 205 ? 73.395  49.365  55.495 1.00 171.02 ? 205 LEU B O   1 
ATOM   1545 C CB  . LEU B 2 205 ? 72.617  50.465  52.533 1.00 241.58 ? 205 LEU B CB  1 
ATOM   1546 C CG  . LEU B 2 205 ? 71.627  51.416  51.861 1.00 275.68 ? 205 LEU B CG  1 
ATOM   1547 C CD1 . LEU B 2 205 ? 71.142  50.857  50.525 1.00 369.79 ? 205 LEU B CD1 1 
ATOM   1548 C CD2 . LEU B 2 205 ? 70.452  51.688  52.797 1.00 184.91 ? 205 LEU B CD2 1 
ATOM   1549 N N   . LEU B 2 206 ? 75.298  49.756  54.397 1.00 152.78 ? 206 LEU B N   1 
ATOM   1550 C CA  . LEU B 2 206 ? 76.065  48.770  55.142 1.00 176.55 ? 206 LEU B CA  1 
ATOM   1551 C C   . LEU B 2 206 ? 76.147  49.142  56.626 1.00 141.53 ? 206 LEU B C   1 
ATOM   1552 O O   . LEU B 2 206 ? 75.881  48.279  57.471 1.00 154.06 ? 206 LEU B O   1 
ATOM   1553 C CB  . LEU B 2 206 ? 77.441  48.611  54.472 1.00 194.94 ? 206 LEU B CB  1 
ATOM   1554 C CG  . LEU B 2 206 ? 78.340  47.535  55.075 1.00 242.74 ? 206 LEU B CG  1 
ATOM   1555 C CD1 . LEU B 2 206 ? 79.159  46.839  53.988 1.00 271.60 ? 206 LEU B CD1 1 
ATOM   1556 C CD2 . LEU B 2 206 ? 79.257  48.117  56.141 1.00 197.18 ? 206 LEU B CD2 1 
ATOM   1557 N N   . ALA B 2 207 ? 76.504  50.390  56.958 1.00 171.23 ? 207 ALA B N   1 
ATOM   1558 C CA  . ALA B 2 207 ? 76.528  50.880  58.343 1.00 176.34 ? 207 ALA B CA  1 
ATOM   1559 C C   . ALA B 2 207 ? 75.154  50.814  59.027 1.00 137.33 ? 207 ALA B C   1 
ATOM   1560 O O   . ALA B 2 207 ? 75.050  50.402  60.175 1.00 133.50 ? 207 ALA B O   1 
ATOM   1561 C CB  . ALA B 2 207 ? 77.051  52.294  58.385 1.00 153.85 ? 207 ALA B CB  1 
ATOM   1562 N N   . LEU B 2 208 ? 74.100  51.198  58.310 1.00 126.37 ? 208 LEU B N   1 
ATOM   1563 C CA  . LEU B 2 208 ? 72.756  51.300  58.855 1.00 125.07 ? 208 LEU B CA  1 
ATOM   1564 C C   . LEU B 2 208 ? 72.129  49.915  59.078 1.00 143.62 ? 208 LEU B C   1 
ATOM   1565 O O   . LEU B 2 208 ? 71.399  49.722  60.034 1.00 126.05 ? 208 LEU B O   1 
ATOM   1566 C CB  . LEU B 2 208 ? 71.931  52.155  57.885 1.00 130.70 ? 208 LEU B CB  1 
ATOM   1567 C CG  . LEU B 2 208 ? 70.689  52.801  58.472 1.00 149.32 ? 208 LEU B CG  1 
ATOM   1568 C CD1 . LEU B 2 208 ? 71.093  53.856  59.484 1.00 197.50 ? 208 LEU B CD1 1 
ATOM   1569 C CD2 . LEU B 2 208 ? 69.861  53.445  57.391 1.00 179.89 ? 208 LEU B CD2 1 
ATOM   1570 N N   . ALA B 2 209 ? 72.404  48.940  58.205 1.00 177.70 ? 209 ALA B N   1 
ATOM   1571 C CA  . ALA B 2 209 ? 71.987  47.560  58.387 1.00 182.62 ? 209 ALA B CA  1 
ATOM   1572 C C   . ALA B 2 209 ? 72.773  46.913  59.526 1.00 143.08 ? 209 ALA B C   1 
ATOM   1573 O O   . ALA B 2 209 ? 72.183  46.166  60.321 1.00 187.52 ? 209 ALA B O   1 
ATOM   1574 C CB  . ALA B 2 209 ? 72.148  46.803  57.080 1.00 241.90 ? 209 ALA B CB  1 
ATOM   1575 N N   . LEU B 2 210 ? 74.084  47.175  59.618 1.00 125.50 ? 210 LEU B N   1 
ATOM   1576 C CA  . LEU B 2 210 ? 74.915  46.620  60.686 1.00 167.21 ? 210 LEU B CA  1 
ATOM   1577 C C   . LEU B 2 210 ? 74.414  47.030  62.078 1.00 127.00 ? 210 LEU B C   1 
ATOM   1578 O O   . LEU B 2 210 ? 74.337  46.194  62.976 1.00 145.54 ? 210 LEU B O   1 
ATOM   1579 C CB  . LEU B 2 210 ? 76.373  47.039  60.459 1.00 186.13 ? 210 LEU B CB  1 
ATOM   1580 C CG  . LEU B 2 210 ? 77.382  46.599  61.519 1.00 182.99 ? 210 LEU B CG  1 
ATOM   1581 C CD1 . LEU B 2 210 ? 77.438  45.083  61.675 1.00 265.41 ? 210 LEU B CD1 1 
ATOM   1582 C CD2 . LEU B 2 210 ? 78.742  47.095  61.137 1.00 184.61 ? 210 LEU B CD2 1 
ATOM   1583 N N   . ILE B 2 211 ? 74.048  48.290  62.263 1.00 124.13 ? 211 ILE B N   1 
ATOM   1584 C CA  . ILE B 2 211 ? 73.426  48.741  63.497 1.00 134.03 ? 211 ILE B CA  1 
ATOM   1585 C C   . ILE B 2 211 ? 72.160  47.931  63.821 1.00 139.87 ? 211 ILE B C   1 
ATOM   1586 O O   . ILE B 2 211 ? 71.947  47.589  64.979 1.00 204.77 ? 211 ILE B O   1 
ATOM   1587 C CB  . ILE B 2 211 ? 73.191  50.273  63.417 1.00 164.74 ? 211 ILE B CB  1 
ATOM   1588 C CG1 . ILE B 2 211 ? 74.546  50.983  63.528 1.00 153.30 ? 211 ILE B CG1 1 
ATOM   1589 C CG2 . ILE B 2 211 ? 72.169  50.830  64.420 1.00 117.25 ? 211 ILE B CG2 1 
ATOM   1590 C CD1 . ILE B 2 211 ? 74.499  52.439  63.140 1.00 180.13 ? 211 ILE B CD1 1 
ATOM   1591 N N   . ILE B 2 212 ? 71.316  47.602  62.839 1.00 136.78 ? 212 ILE B N   1 
ATOM   1592 C CA  . ILE B 2 212 ? 70.093  46.846  63.085 1.00 149.24 ? 212 ILE B CA  1 
ATOM   1593 C C   . ILE B 2 212 ? 70.428  45.388  63.438 1.00 196.16 ? 212 ILE B C   1 
ATOM   1594 O O   . ILE B 2 212 ? 69.832  44.863  64.392 1.00 243.11 ? 212 ILE B O   1 
ATOM   1595 C CB  . ILE B 2 212 ? 69.118  46.977  61.899 1.00 162.02 ? 212 ILE B CB  1 
ATOM   1596 C CG1 . ILE B 2 212 ? 68.542  48.387  61.841 1.00 172.10 ? 212 ILE B CG1 1 
ATOM   1597 C CG2 . ILE B 2 212 ? 67.999  45.947  61.971 1.00 216.23 ? 212 ILE B CG2 1 
ATOM   1598 C CD1 . ILE B 2 212 ? 67.754  48.728  60.564 1.00 232.42 ? 212 ILE B CD1 1 
ATOM   1599 N N   . LEU B 2 213 ? 71.355  44.720  62.711 1.00 166.19 ? 213 LEU B N   1 
ATOM   1600 C CA  . LEU B 2 213 ? 71.656  43.316  63.006 1.00 199.02 ? 213 LEU B CA  1 
ATOM   1601 C C   . LEU B 2 213 ? 72.348  43.181  64.377 1.00 179.76 ? 213 LEU B C   1 
ATOM   1602 O O   . LEU B 2 213 ? 72.093  42.208  65.099 1.00 212.62 ? 213 LEU B O   1 
ATOM   1603 C CB  . LEU B 2 213 ? 72.412  42.656  61.837 1.00 211.85 ? 213 LEU B CB  1 
ATOM   1604 C CG  . LEU B 2 213 ? 73.931  42.817  61.746 1.00 242.25 ? 213 LEU B CG  1 
ATOM   1605 C CD1 . LEU B 2 213 ? 74.684  41.732  62.523 1.00 243.72 ? 213 LEU B CD1 1 
ATOM   1606 C CD2 . LEU B 2 213 ? 74.375  42.783  60.289 1.00 301.46 ? 213 LEU B CD2 1 
ATOM   1607 N N   . LEU B 2 214 ? 73.193  44.144  64.765 1.00 155.68 ? 214 LEU B N   1 
ATOM   1608 C CA  . LEU B 2 214 ? 73.715  44.218  66.130 1.00 174.97 ? 214 LEU B CA  1 
ATOM   1609 C C   . LEU B 2 214 ? 72.590  44.430  67.156 1.00 155.87 ? 214 LEU B C   1 
ATOM   1610 O O   . LEU B 2 214 ? 72.604  43.800  68.208 1.00 187.62 ? 214 LEU B O   1 
ATOM   1611 C CB  . LEU B 2 214 ? 74.782  45.315  66.196 1.00 180.90 ? 214 LEU B CB  1 
ATOM   1612 C CG  . LEU B 2 214 ? 76.079  45.008  65.446 1.00 215.93 ? 214 LEU B CG  1 
ATOM   1613 C CD1 . LEU B 2 214 ? 76.925  46.257  65.321 1.00 258.92 ? 214 LEU B CD1 1 
ATOM   1614 C CD2 . LEU B 2 214 ? 76.879  43.914  66.141 1.00 252.72 ? 214 LEU B CD2 1 
ATOM   1615 N N   . GLY B 2 215 ? 71.603  45.284  66.851 1.00 165.34 ? 215 GLY B N   1 
ATOM   1616 C CA  . GLY B 2 215 ? 70.403  45.455  67.664 1.00 174.87 ? 215 GLY B CA  1 
ATOM   1617 C C   . GLY B 2 215 ? 69.595  44.163  67.845 1.00 208.22 ? 215 GLY B C   1 
ATOM   1618 O O   . GLY B 2 215 ? 69.102  43.899  68.943 1.00 229.77 ? 215 GLY B O   1 
ATOM   1619 N N   . PHE B 2 216 ? 69.469  43.346  66.788 1.00 218.68 ? 216 PHE B N   1 
ATOM   1620 C CA  . PHE B 2 216 ? 68.787  42.058  66.889 1.00 261.37 ? 216 PHE B CA  1 
ATOM   1621 C C   . PHE B 2 216 ? 69.545  41.060  67.779 1.00 226.24 ? 216 PHE B C   1 
ATOM   1622 O O   . PHE B 2 216 ? 68.892  40.408  68.596 1.00 169.76 ? 216 PHE B O   1 
ATOM   1623 C CB  . PHE B 2 216 ? 68.486  41.475  65.500 1.00 301.57 ? 216 PHE B CB  1 
ATOM   1624 C CG  . PHE B 2 216 ? 67.251  42.039  64.827 1.00 336.23 ? 216 PHE B CG  1 
ATOM   1625 C CD1 . PHE B 2 216 ? 66.011  41.997  65.463 1.00 325.76 ? 216 PHE B CD1 1 
ATOM   1626 C CD2 . PHE B 2 216 ? 67.311  42.607  63.556 1.00 401.77 ? 216 PHE B CD2 1 
ATOM   1627 C CE1 . PHE B 2 216 ? 64.870  42.509  64.855 1.00 339.11 ? 216 PHE B CE1 1 
ATOM   1628 C CE2 . PHE B 2 216 ? 66.168  43.119  62.949 1.00 419.06 ? 216 PHE B CE2 1 
ATOM   1629 C CZ  . PHE B 2 216 ? 64.949  43.072  63.599 1.00 387.98 ? 216 PHE B CZ  1 
ATOM   1630 N N   . VAL B 2 217 ? 70.880  40.924  67.669 1.00 210.24 ? 217 VAL B N   1 
ATOM   1631 C CA  . VAL B 2 217 ? 71.604  40.012  68.564 1.00 237.51 ? 217 VAL B CA  1 
ATOM   1632 C C   . VAL B 2 217 ? 71.609  40.527  70.012 1.00 184.61 ? 217 VAL B C   1 
ATOM   1633 O O   . VAL B 2 217 ? 71.634  39.715  70.935 1.00 278.44 ? 217 VAL B O   1 
ATOM   1634 C CB  . VAL B 2 217 ? 73.030  39.650  68.086 1.00 277.46 ? 217 VAL B CB  1 
ATOM   1635 C CG1 . VAL B 2 217 ? 72.976  38.959  66.732 1.00 323.25 ? 217 VAL B CG1 1 
ATOM   1636 C CG2 . VAL B 2 217 ? 73.997  40.825  68.051 1.00 234.09 ? 217 VAL B CG2 1 
ATOM   1637 N N   . GLN B 2 218 ? 71.558  41.843  70.228 1.00 187.92 ? 218 GLN B N   1 
ATOM   1638 C CA  . GLN B 2 218 ? 71.362  42.423  71.555 1.00 225.46 ? 218 GLN B CA  1 
ATOM   1639 C C   . GLN B 2 218 ? 70.030  41.958  72.166 1.00 182.53 ? 218 GLN B C   1 
ATOM   1640 O O   . GLN B 2 218 ? 70.006  41.586  73.342 1.00 244.27 ? 218 GLN B O   1 
ATOM   1641 C CB  . GLN B 2 218 ? 71.483  43.952  71.457 1.00 294.64 ? 218 GLN B CB  1 
ATOM   1642 C CG  . GLN B 2 218 ? 71.247  44.724  72.749 1.00 301.34 ? 218 GLN B CG  1 
ATOM   1643 C CD  . GLN B 2 218 ? 72.325  44.568  73.801 1.00 303.25 ? 218 GLN B CD  1 
ATOM   1644 O OE1 . GLN B 2 218 ? 73.374  43.963  73.581 1.00 254.19 ? 218 GLN B OE1 1 
ATOM   1645 N NE2 . GLN B 2 218 ? 72.071  45.124  74.978 1.00 327.47 ? 218 GLN B NE2 1 
ATOM   1646 N N   . ILE B 2 219 ? 68.934  41.958  71.389 1.00 150.21 ? 219 ILE B N   1 
ATOM   1647 C CA  . ILE B 2 219 ? 67.646  41.418  71.835 1.00 236.66 ? 219 ILE B CA  1 
ATOM   1648 C C   . ILE B 2 219 ? 67.683  39.882  71.990 1.00 347.49 ? 219 ILE B C   1 
ATOM   1649 O O   . ILE B 2 219 ? 67.109  39.360  72.954 1.00 390.34 ? 219 ILE B O   1 
ATOM   1650 C CB  . ILE B 2 219 ? 66.515  41.918  70.901 1.00 258.98 ? 219 ILE B CB  1 
ATOM   1651 C CG1 . ILE B 2 219 ? 66.186  43.385  71.190 1.00 245.46 ? 219 ILE B CG1 1 
ATOM   1652 C CG2 . ILE B 2 219 ? 65.249  41.057  70.955 1.00 328.64 ? 219 ILE B CG2 1 
ATOM   1653 C CD1 . ILE B 2 219 ? 65.485  43.651  72.526 1.00 241.06 ? 219 ILE B CD1 1 
ATOM   1654 N N   . GLY B 2 220 ? 68.344  39.157  71.068 1.00 362.23 ? 220 GLY B N   1 
ATOM   1655 C CA  . GLY B 2 220 ? 68.514  37.706  71.151 1.00 325.70 ? 220 GLY B CA  1 
ATOM   1656 C C   . GLY B 2 220 ? 69.222  37.235  72.430 1.00 315.64 ? 220 GLY B C   1 
ATOM   1657 O O   . GLY B 2 220 ? 68.870  36.190  72.971 1.00 321.64 ? 220 GLY B O   1 
ATOM   1658 N N   . LYS B 2 221 ? 70.212  38.015  72.903 1.00 343.52 ? 221 LYS B N   1 
ATOM   1659 C CA  . LYS B 2 221 ? 70.878  37.824  74.189 1.00 342.06 ? 221 LYS B CA  1 
ATOM   1660 C C   . LYS B 2 221 ? 70.014  38.325  75.359 1.00 323.16 ? 221 LYS B C   1 
ATOM   1661 O O   . LYS B 2 221 ? 69.993  37.687  76.414 1.00 339.82 ? 221 LYS B O   1 
ATOM   1662 C CB  . LYS B 2 221 ? 72.244  38.519  74.135 1.00 344.87 ? 221 LYS B CB  1 
ATOM   1663 C CG  . LYS B 2 221 ? 73.129  38.337  75.358 1.00 356.47 ? 221 LYS B CG  1 
ATOM   1664 C CD  . LYS B 2 221 ? 74.523  38.908  75.181 1.00 350.20 ? 221 LYS B CD  1 
ATOM   1665 C CE  . LYS B 2 221 ? 75.389  38.119  74.217 1.00 358.85 ? 221 LYS B CE  1 
ATOM   1666 N NZ  . LYS B 2 221 ? 76.809  38.544  74.264 1.00 354.48 ? 221 LYS B NZ  1 
ATOM   1667 N N   . GLY B 2 222 ? 69.320  39.463  75.183 1.00 311.35 ? 222 GLY B N   1 
ATOM   1668 C CA  . GLY B 2 222 ? 68.385  39.998  76.164 1.00 294.83 ? 222 GLY B CA  1 
ATOM   1669 C C   . GLY B 2 222 ? 67.034  39.299  76.117 1.00 286.16 ? 222 GLY B C   1 
ATOM   1670 O O   . GLY B 2 222 ? 66.027  39.958  76.468 1.00 280.80 ? 222 GLY B O   1 
ATOM   1671 N N   . PHE B 2 233 ? 60.321  55.508  77.283 1.00 300.56 ? 233 PHE B N   1 
ATOM   1672 C CA  . PHE B 2 233 ? 59.062  54.697  77.307 1.00 275.43 ? 233 PHE B CA  1 
ATOM   1673 C C   . PHE B 2 233 ? 57.851  55.495  77.824 1.00 237.92 ? 233 PHE B C   1 
ATOM   1674 O O   . PHE B 2 233 ? 56.723  55.141  77.495 1.00 231.64 ? 233 PHE B O   1 
ATOM   1675 C CB  . PHE B 2 233 ? 59.303  53.409  78.110 1.00 269.53 ? 233 PHE B CB  1 
ATOM   1676 C CG  . PHE B 2 233 ? 60.412  52.534  77.557 1.00 346.61 ? 233 PHE B CG  1 
ATOM   1677 C CD1 . PHE B 2 233 ? 60.250  51.815  76.372 1.00 330.01 ? 233 PHE B CD1 1 
ATOM   1678 C CD2 . PHE B 2 233 ? 61.640  52.441  78.209 1.00 346.82 ? 233 PHE B CD2 1 
ATOM   1679 C CE1 . PHE B 2 233 ? 61.274  51.013  75.864 1.00 277.43 ? 233 PHE B CE1 1 
ATOM   1680 C CE2 . PHE B 2 233 ? 62.666  51.637  77.706 1.00 293.17 ? 233 PHE B CE2 1 
ATOM   1681 C CZ  . PHE B 2 233 ? 62.484  50.926  76.531 1.00 269.17 ? 233 PHE B CZ  1 
ATOM   1682 N N   . GLU B 2 234 ? 58.072  56.566  78.610 1.00 265.43 ? 234 GLU B N   1 
ATOM   1683 C CA  . GLU B 2 234 ? 57.009  57.412  79.155 1.00 321.56 ? 234 GLU B CA  1 
ATOM   1684 C C   . GLU B 2 234 ? 56.606  58.553  78.200 1.00 329.67 ? 234 GLU B C   1 
ATOM   1685 O O   . GLU B 2 234 ? 55.426  58.911  78.122 1.00 279.68 ? 234 GLU B O   1 
ATOM   1686 C CB  . GLU B 2 234 ? 57.427  58.058  80.487 1.00 349.81 ? 234 GLU B CB  1 
ATOM   1687 C CG  . GLU B 2 234 ? 58.208  57.157  81.449 1.00 350.98 ? 234 GLU B CG  1 
ATOM   1688 C CD  . GLU B 2 234 ? 59.725  57.231  81.337 1.00 358.32 ? 234 GLU B CD  1 
ATOM   1689 O OE1 . GLU B 2 234 ? 60.230  57.402  80.207 1.00 368.88 ? 234 GLU B OE1 1 
ATOM   1690 O OE2 . GLU B 2 234 ? 60.400  57.114  82.380 1.00 400.67 ? 234 GLU B OE2 1 
ATOM   1691 N N   . GLY B 2 235 ? 57.585  59.142  77.491 1.00 362.63 ? 235 GLY B N   1 
ATOM   1692 C CA  . GLY B 2 235 ? 57.444  60.444  76.842 1.00 364.69 ? 235 GLY B CA  1 
ATOM   1693 C C   . GLY B 2 235 ? 57.437  61.603  77.848 1.00 355.73 ? 235 GLY B C   1 
ATOM   1694 O O   . GLY B 2 235 ? 56.405  62.242  78.062 1.00 335.11 ? 235 GLY B O   1 
ATOM   1695 N N   . THR B 2 236 ? 58.602  61.886  78.461 1.00 333.17 ? 236 THR B N   1 
ATOM   1696 C CA  . THR B 2 236 ? 58.707  62.752  79.644 1.00 328.94 ? 236 THR B CA  1 
ATOM   1697 C C   . THR B 2 236 ? 58.598  64.257  79.334 1.00 292.30 ? 236 THR B C   1 
ATOM   1698 O O   . THR B 2 236 ? 58.562  65.061  80.270 1.00 325.50 ? 236 THR B O   1 
ATOM   1699 C CB  . THR B 2 236 ? 59.994  62.465  80.445 1.00 322.18 ? 236 THR B CB  1 
ATOM   1700 O OG1 . THR B 2 236 ? 61.148  62.648  79.622 1.00 319.96 ? 236 THR B OG1 1 
ATOM   1701 C CG2 . THR B 2 236 ? 60.019  61.073  81.040 1.00 288.45 ? 236 THR B CG2 1 
ATOM   1702 N N   . LYS B 2 237 ? 58.545  64.660  78.050 1.00 234.78 ? 237 LYS B N   1 
ATOM   1703 C CA  . LYS B 2 237 ? 58.106  65.998  77.650 1.00 252.65 ? 237 LYS B CA  1 
ATOM   1704 C C   . LYS B 2 237 ? 56.981  65.888  76.620 1.00 270.87 ? 237 LYS B C   1 
ATOM   1705 O O   . LYS B 2 237 ? 56.994  64.979  75.796 1.00 308.25 ? 237 LYS B O   1 
ATOM   1706 C CB  . LYS B 2 237 ? 59.273  66.825  77.092 1.00 268.81 ? 237 LYS B CB  1 
ATOM   1707 C CG  . LYS B 2 237 ? 60.259  67.296  78.147 1.00 328.86 ? 237 LYS B CG  1 
ATOM   1708 C CD  . LYS B 2 237 ? 61.174  68.434  77.669 1.00 309.52 ? 237 LYS B CD  1 
ATOM   1709 C CE  . LYS B 2 237 ? 62.237  68.039  76.660 1.00 258.05 ? 237 LYS B CE  1 
ATOM   1710 N NZ  . LYS B 2 237 ? 63.413  67.374  77.275 1.00 263.78 ? 237 LYS B NZ  1 
ATOM   1711 N N   . LEU B 2 238 ? 56.012  66.823  76.681 1.00 306.88 ? 238 LEU B N   1 
ATOM   1712 C CA  . LEU B 2 238 ? 54.872  66.835  75.760 1.00 336.75 ? 238 LEU B CA  1 
ATOM   1713 C C   . LEU B 2 238 ? 54.439  68.256  75.351 1.00 313.11 ? 238 LEU B C   1 
ATOM   1714 O O   . LEU B 2 238 ? 53.315  68.451  74.881 1.00 291.64 ? 238 LEU B O   1 
ATOM   1715 C CB  . LEU B 2 238 ? 53.741  66.050  76.444 1.00 369.47 ? 238 LEU B CB  1 
ATOM   1716 C CG  . LEU B 2 238 ? 52.650  65.441  75.555 1.00 396.78 ? 238 LEU B CG  1 
ATOM   1717 C CD1 . LEU B 2 238 ? 53.211  64.439  74.552 1.00 374.17 ? 238 LEU B CD1 1 
ATOM   1718 C CD2 . LEU B 2 238 ? 51.590  64.774  76.418 1.00 425.12 ? 238 LEU B CD2 1 
ATOM   1719 N N   . ASP B 2 239 ? 55.331  69.256  75.486 1.00 300.14 ? 239 ASP B N   1 
ATOM   1720 C CA  . ASP B 2 239 ? 55.101  70.606  74.985 1.00 291.25 ? 239 ASP B CA  1 
ATOM   1721 C C   . ASP B 2 239 ? 55.068  70.614  73.449 1.00 272.89 ? 239 ASP B C   1 
ATOM   1722 O O   . ASP B 2 239 ? 55.988  70.094  72.812 1.00 299.88 ? 239 ASP B O   1 
ATOM   1723 C CB  . ASP B 2 239 ? 56.183  71.552  75.524 1.00 292.26 ? 239 ASP B CB  1 
ATOM   1724 C CG  . ASP B 2 239 ? 56.123  72.999  75.042 1.00 309.94 ? 239 ASP B CG  1 
ATOM   1725 O OD1 . ASP B 2 239 ? 55.081  73.400  74.470 1.00 310.11 ? 239 ASP B OD1 1 
ATOM   1726 O OD2 . ASP B 2 239 ? 57.122  73.729  75.241 1.00 281.17 ? 239 ASP B OD2 1 
ATOM   1727 N N   . VAL B 2 240 ? 54.025  71.241  72.864 1.00 262.06 ? 240 VAL B N   1 
ATOM   1728 C CA  . VAL B 2 240 ? 53.909  71.440  71.422 1.00 235.74 ? 240 VAL B CA  1 
ATOM   1729 C C   . VAL B 2 240 ? 55.145  72.165  70.876 1.00 174.15 ? 240 VAL B C   1 
ATOM   1730 O O   . VAL B 2 240 ? 55.592  71.866  69.759 1.00 242.23 ? 240 VAL B O   1 
ATOM   1731 C CB  . VAL B 2 240 ? 52.585  72.167  71.084 1.00 289.46 ? 240 VAL B CB  1 
ATOM   1732 C CG1 . VAL B 2 240 ? 52.537  72.766  69.676 1.00 339.77 ? 240 VAL B CG1 1 
ATOM   1733 C CG2 . VAL B 2 240 ? 51.400  71.237  71.292 1.00 309.05 ? 240 VAL B CG2 1 
ATOM   1734 N N   . GLY B 2 241 ? 55.709  73.114  71.636 1.00 195.81 ? 241 GLY B N   1 
ATOM   1735 C CA  . GLY B 2 241 ? 56.967  73.752  71.267 1.00 235.94 ? 241 GLY B CA  1 
ATOM   1736 C C   . GLY B 2 241 ? 58.095  72.757  70.961 1.00 193.60 ? 241 GLY B C   1 
ATOM   1737 O O   . GLY B 2 241 ? 58.635  72.747  69.854 1.00 101.47 ? 241 GLY B O   1 
ATOM   1738 N N   . ASN B 2 242 ? 58.439  71.913  71.944 1.00 209.64 ? 242 ASN B N   1 
ATOM   1739 C CA  . ASN B 2 242 ? 59.490  70.919  71.765 1.00 174.31 ? 242 ASN B CA  1 
ATOM   1740 C C   . ASN B 2 242 ? 59.104  69.883  70.703 1.00 161.02 ? 242 ASN B C   1 
ATOM   1741 O O   . ASN B 2 242 ? 59.950  69.474  69.924 1.00 152.74 ? 242 ASN B O   1 
ATOM   1742 C CB  . ASN B 2 242 ? 59.835  70.216  73.079 1.00 191.07 ? 242 ASN B CB  1 
ATOM   1743 C CG  . ASN B 2 242 ? 60.455  71.131  74.107 1.00 223.23 ? 242 ASN B CG  1 
ATOM   1744 O OD1 . ASN B 2 242 ? 59.781  71.534  75.050 1.00 299.07 ? 242 ASN B OD1 1 
ATOM   1745 N ND2 . ASN B 2 242 ? 61.725  71.463  73.940 1.00 253.39 ? 242 ASN B ND2 1 
ATOM   1746 N N   . ILE B 2 243 ? 57.842  69.446  70.626 1.00 144.51 ? 243 ILE B N   1 
ATOM   1747 C CA  . ILE B 2 243 ? 57.526  68.364  69.701 1.00 151.27 ? 243 ILE B CA  1 
ATOM   1748 C C   . ILE B 2 243 ? 57.669  68.829  68.231 1.00 171.92 ? 243 ILE B C   1 
ATOM   1749 O O   . ILE B 2 243 ? 57.939  68.001  67.362 1.00 188.02 ? 243 ILE B O   1 
ATOM   1750 C CB  . ILE B 2 243 ? 56.154  67.712  70.027 1.00 209.31 ? 243 ILE B CB  1 
ATOM   1751 C CG1 . ILE B 2 243 ? 56.208  66.204  69.772 1.00 238.16 ? 243 ILE B CG1 1 
ATOM   1752 C CG2 . ILE B 2 243 ? 54.978  68.347  69.288 1.00 270.84 ? 243 ILE B CG2 1 
ATOM   1753 C CD1 . ILE B 2 243 ? 57.115  65.448  70.713 1.00 199.96 ? 243 ILE B CD1 1 
ATOM   1754 N N   . VAL B 2 244 ? 57.534  70.124  67.931 1.00 179.20 ? 244 VAL B N   1 
ATOM   1755 C CA  . VAL B 2 244 ? 57.868  70.660  66.610 1.00 174.25 ? 244 VAL B CA  1 
ATOM   1756 C C   . VAL B 2 244 ? 59.382  70.629  66.356 1.00 132.04 ? 244 VAL B C   1 
ATOM   1757 O O   . VAL B 2 244 ? 59.788  70.419  65.218 1.00 158.91 ? 244 VAL B O   1 
ATOM   1758 C CB  . VAL B 2 244 ? 57.251  72.068  66.429 1.00 209.24 ? 244 VAL B CB  1 
ATOM   1759 C CG1 . VAL B 2 244 ? 57.867  72.911  65.305 1.00 182.82 ? 244 VAL B CG1 1 
ATOM   1760 C CG2 . VAL B 2 244 ? 55.748  71.928  66.235 1.00 201.55 ? 244 VAL B CG2 1 
ATOM   1761 N N   . LEU B 2 245 ? 60.237  70.818  67.368 1.00 122.16 ? 245 LEU B N   1 
ATOM   1762 C CA  . LEU B 2 245 ? 61.681  70.654  67.197 1.00 120.51 ? 245 LEU B CA  1 
ATOM   1763 C C   . LEU B 2 245 ? 62.091  69.172  67.129 1.00 109.93 ? 245 LEU B C   1 
ATOM   1764 O O   . LEU B 2 245 ? 63.106  68.834  66.511 1.00 107.35 ? 245 LEU B O   1 
ATOM   1765 C CB  . LEU B 2 245 ? 62.424  71.374  68.333 1.00 119.52 ? 245 LEU B CB  1 
ATOM   1766 C CG  . LEU B 2 245 ? 62.157  72.859  68.447 1.00 145.30 ? 245 LEU B CG  1 
ATOM   1767 C CD1 . LEU B 2 245 ? 63.110  73.464  69.479 1.00 165.13 ? 245 LEU B CD1 1 
ATOM   1768 C CD2 . LEU B 2 245 ? 62.315  73.541  67.091 1.00 163.78 ? 245 LEU B CD2 1 
ATOM   1769 N N   . ALA B 2 246 ? 61.318  68.265  67.746 1.00 104.21 ? 246 ALA B N   1 
ATOM   1770 C CA  . ALA B 2 246 ? 61.499  66.834  67.553 1.00 105.38 ? 246 ALA B CA  1 
ATOM   1771 C C   . ALA B 2 246 ? 61.146  66.498  66.113 1.00 114.30 ? 246 ALA B C   1 
ATOM   1772 O O   . ALA B 2 246 ? 61.906  65.806  65.463 1.00 104.86 ? 246 ALA B O   1 
ATOM   1773 C CB  . ALA B 2 246 ? 60.635  66.090  68.559 1.00 173.47 ? 246 ALA B CB  1 
ATOM   1774 N N   . LEU B 2 247 ? 59.998  66.993  65.597 1.00 137.20 ? 247 LEU B N   1 
ATOM   1775 C CA  . LEU B 2 247 ? 59.608  66.750  64.222 1.00 131.89 ? 247 LEU B CA  1 
ATOM   1776 C C   . LEU B 2 247 ? 60.654  67.319  63.253 1.00 141.34 ? 247 LEU B C   1 
ATOM   1777 O O   . LEU B 2 247 ? 61.022  66.630  62.320 1.00 137.65 ? 247 LEU B O   1 
ATOM   1778 C CB  . LEU B 2 247 ? 58.216  67.339  63.985 1.00 153.65 ? 247 LEU B CB  1 
ATOM   1779 C CG  . LEU B 2 247 ? 57.064  66.501  64.511 1.00 214.84 ? 247 LEU B CG  1 
ATOM   1780 C CD1 . LEU B 2 247 ? 55.776  67.324  64.504 1.00 319.86 ? 247 LEU B CD1 1 
ATOM   1781 C CD2 . LEU B 2 247 ? 56.892  65.227  63.683 1.00 193.38 ? 247 LEU B CD2 1 
ATOM   1782 N N   . TYR B 2 248 ? 61.154  68.545  63.418 1.00 140.27 ? 248 TYR B N   1 
ATOM   1783 C CA  . TYR B 2 248 ? 62.237  69.060  62.589 1.00 129.32 ? 248 TYR B CA  1 
ATOM   1784 C C   . TYR B 2 248 ? 63.452  68.150  62.575 1.00 99.90  ? 248 TYR B C   1 
ATOM   1785 O O   . TYR B 2 248 ? 63.988  67.902  61.499 1.00 154.94 ? 248 TYR B O   1 
ATOM   1786 C CB  . TYR B 2 248 ? 62.704  70.425  63.110 1.00 129.29 ? 248 TYR B CB  1 
ATOM   1787 C CG  . TYR B 2 248 ? 61.908  71.660  62.716 1.00 126.40 ? 248 TYR B CG  1 
ATOM   1788 C CD1 . TYR B 2 248 ? 60.950  71.650  61.718 1.00 125.59 ? 248 TYR B CD1 1 
ATOM   1789 C CD2 . TYR B 2 248 ? 62.154  72.870  63.348 1.00 138.87 ? 248 TYR B CD2 1 
ATOM   1790 C CE1 . TYR B 2 248 ? 60.274  72.806  61.362 1.00 193.15 ? 248 TYR B CE1 1 
ATOM   1791 C CE2 . TYR B 2 248 ? 61.489  74.036  63.004 1.00 139.40 ? 248 TYR B CE2 1 
ATOM   1792 C CZ  . TYR B 2 248 ? 60.540  74.003  62.000 1.00 195.12 ? 248 TYR B CZ  1 
ATOM   1793 O OH  . TYR B 2 248 ? 59.852  75.136  61.645 1.00 226.38 ? 248 TYR B OH  1 
ATOM   1794 N N   . SER B 2 249 ? 63.908  67.677  63.734 1.00 102.12 ? 249 SER B N   1 
ATOM   1795 C CA  . SER B 2 249 ? 65.058  66.782  63.800 1.00 129.36 ? 249 SER B CA  1 
ATOM   1796 C C   . SER B 2 249 ? 64.746  65.444  63.102 1.00 121.35 ? 249 SER B C   1 
ATOM   1797 O O   . SER B 2 249 ? 65.563  64.868  62.428 1.00 101.78 ? 249 SER B O   1 
ATOM   1798 C CB  . SER B 2 249 ? 65.490  66.553  65.223 1.00 163.39 ? 249 SER B CB  1 
ATOM   1799 O OG  . SER B 2 249 ? 65.802  67.784  65.859 1.00 207.30 ? 249 SER B OG  1 
ATOM   1800 N N   . GLY B 2 250 ? 63.568  64.878  63.251 1.00 154.20 ? 250 GLY B N   1 
ATOM   1801 C CA  . GLY B 2 250 ? 63.286  63.607  62.620 1.00 134.37 ? 250 GLY B CA  1 
ATOM   1802 C C   . GLY B 2 250 ? 63.046  63.742  61.138 1.00 111.46 ? 250 GLY B C   1 
ATOM   1803 O O   . GLY B 2 250 ? 63.415  62.848  60.418 1.00 126.45 ? 250 GLY B O   1 
ATOM   1804 N N   . LEU B 2 251 ? 62.389  64.823  60.675 1.00 139.90 ? 251 LEU B N   1 
ATOM   1805 C CA  . LEU B 2 251 ? 62.111  65.048  59.269 1.00 161.90 ? 251 LEU B CA  1 
ATOM   1806 C C   . LEU B 2 251 ? 63.390  65.290  58.472 1.00 137.90 ? 251 LEU B C   1 
ATOM   1807 O O   . LEU B 2 251 ? 63.414  64.983  57.277 1.00 176.07 ? 251 LEU B O   1 
ATOM   1808 C CB  . LEU B 2 251 ? 61.161  66.241  59.131 1.00 148.71 ? 251 LEU B CB  1 
ATOM   1809 C CG  . LEU B 2 251 ? 59.694  65.970  59.406 1.00 141.99 ? 251 LEU B CG  1 
ATOM   1810 C CD1 . LEU B 2 251 ? 58.903  67.263  59.342 1.00 217.00 ? 251 LEU B CD1 1 
ATOM   1811 C CD2 . LEU B 2 251 ? 59.105  65.000  58.406 1.00 147.78 ? 251 LEU B CD2 1 
ATOM   1812 N N   . PHE B 2 252 ? 64.434  65.840  59.090 1.00 128.35 ? 252 PHE B N   1 
ATOM   1813 C CA  . PHE B 2 252 ? 65.693  66.063  58.405 1.00 135.77 ? 252 PHE B CA  1 
ATOM   1814 C C   . PHE B 2 252 ? 66.207  64.804  57.709 1.00 103.85 ? 252 PHE B C   1 
ATOM   1815 O O   . PHE B 2 252 ? 66.710  64.936  56.578 1.00 138.48 ? 252 PHE B O   1 
ATOM   1816 C CB  . PHE B 2 252 ? 66.751  66.614  59.373 1.00 141.16 ? 252 PHE B CB  1 
ATOM   1817 C CG  . PHE B 2 252 ? 68.070  66.899  58.718 1.00 112.98 ? 252 PHE B CG  1 
ATOM   1818 C CD1 . PHE B 2 252 ? 69.037  65.911  58.578 1.00 147.24 ? 252 PHE B CD1 1 
ATOM   1819 C CD2 . PHE B 2 252 ? 68.311  68.163  58.193 1.00 133.06 ? 252 PHE B CD2 1 
ATOM   1820 C CE1 . PHE B 2 252 ? 70.241  66.181  57.942 1.00 149.11 ? 252 PHE B CE1 1 
ATOM   1821 C CE2 . PHE B 2 252 ? 69.515  68.449  57.570 1.00 113.65 ? 252 PHE B CE2 1 
ATOM   1822 C CZ  . PHE B 2 252 ? 70.456  67.444  57.437 1.00 139.97 ? 252 PHE B CZ  1 
ATOM   1823 N N   . ALA B 2 253 ? 66.115  63.622  58.347 1.00 71.85  ? 253 ALA B N   1 
ATOM   1824 C CA  . ALA B 2 253 ? 66.632  62.377  57.777 1.00 83.17  ? 253 ALA B CA  1 
ATOM   1825 C C   . ALA B 2 253 ? 65.876  61.973  56.507 1.00 130.05 ? 253 ALA B C   1 
ATOM   1826 O O   . ALA B 2 253 ? 66.503  61.489  55.564 1.00 192.85 ? 253 ALA B O   1 
ATOM   1827 C CB  . ALA B 2 253 ? 66.638  61.277  58.763 1.00 116.74 ? 253 ALA B CB  1 
ATOM   1828 N N   . TYR B 2 254 ? 64.564  62.221  56.417 1.00 108.35 ? 254 TYR B N   1 
ATOM   1829 C CA  . TYR B 2 254 ? 63.846  61.932  55.176 1.00 141.58 ? 254 TYR B CA  1 
ATOM   1830 C C   . TYR B 2 254 ? 64.051  62.940  54.013 1.00 148.95 ? 254 TYR B C   1 
ATOM   1831 O O   . TYR B 2 254 ? 63.365  62.858  52.989 1.00 169.89 ? 254 TYR B O   1 
ATOM   1832 C CB  . TYR B 2 254 ? 62.360  61.924  55.552 1.00 144.79 ? 254 TYR B CB  1 
ATOM   1833 C CG  . TYR B 2 254 ? 61.896  60.812  56.469 1.00 127.08 ? 254 TYR B CG  1 
ATOM   1834 C CD1 . TYR B 2 254 ? 61.447  59.590  55.951 1.00 121.68 ? 254 TYR B CD1 1 
ATOM   1835 C CD2 . TYR B 2 254 ? 61.868  61.002  57.837 1.00 133.59 ? 254 TYR B CD2 1 
ATOM   1836 C CE1 . TYR B 2 254 ? 61.016  58.578  56.785 1.00 133.31 ? 254 TYR B CE1 1 
ATOM   1837 C CE2 . TYR B 2 254 ? 61.423  59.998  58.681 1.00 139.44 ? 254 TYR B CE2 1 
ATOM   1838 C CZ  . TYR B 2 254 ? 60.994  58.789  58.153 1.00 149.81 ? 254 TYR B CZ  1 
ATOM   1839 O OH  . TYR B 2 254 ? 60.547  57.818  59.002 1.00 191.31 ? 254 TYR B OH  1 
ATOM   1840 N N   . GLY B 2 255 ? 64.951  63.926  54.125 1.00 212.94 ? 255 GLY B N   1 
ATOM   1841 C CA  . GLY B 2 255 ? 64.842  65.167  53.348 1.00 263.05 ? 255 GLY B CA  1 
ATOM   1842 C C   . GLY B 2 255 ? 65.322  65.120  51.889 1.00 289.55 ? 255 GLY B C   1 
ATOM   1843 O O   . GLY B 2 255 ? 65.767  66.153  51.371 1.00 354.57 ? 255 GLY B O   1 
ATOM   1844 N N   . GLY B 2 256 ? 65.211  63.945  51.228 1.00 234.70 ? 256 GLY B N   1 
ATOM   1845 C CA  . GLY B 2 256 ? 65.553  63.753  49.821 1.00 235.94 ? 256 GLY B CA  1 
ATOM   1846 C C   . GLY B 2 256 ? 64.393  63.934  48.823 1.00 153.63 ? 256 GLY B C   1 
ATOM   1847 O O   . GLY B 2 256 ? 64.624  64.330  47.685 1.00 213.70 ? 256 GLY B O   1 
ATOM   1848 N N   . TRP B 2 257 ? 63.155  63.642  49.229 1.00 132.55 ? 257 TRP B N   1 
ATOM   1849 C CA  . TRP B 2 257 ? 62.045  63.470  48.287 1.00 176.23 ? 257 TRP B CA  1 
ATOM   1850 C C   . TRP B 2 257 ? 61.633  64.719  47.458 1.00 153.13 ? 257 TRP B C   1 
ATOM   1851 O O   . TRP B 2 257 ? 61.146  64.603  46.336 1.00 111.73 ? 257 TRP B O   1 
ATOM   1852 C CB  . TRP B 2 257 ? 60.838  62.873  49.019 1.00 143.66 ? 257 TRP B CB  1 
ATOM   1853 C CG  . TRP B 2 257 ? 60.396  63.524  50.290 1.00 113.50 ? 257 TRP B CG  1 
ATOM   1854 C CD1 . TRP B 2 257 ? 60.648  63.057  51.543 1.00 150.35 ? 257 TRP B CD1 1 
ATOM   1855 C CD2 . TRP B 2 257 ? 59.595  64.720  50.466 1.00 121.19 ? 257 TRP B CD2 1 
ATOM   1856 N NE1 . TRP B 2 257 ? 60.081  63.877  52.495 1.00 170.11 ? 257 TRP B NE1 1 
ATOM   1857 C CE2 . TRP B 2 257 ? 59.431  64.909  51.854 1.00 148.34 ? 257 TRP B CE2 1 
ATOM   1858 C CE3 . TRP B 2 257 ? 59.004  65.652  49.611 1.00 144.33 ? 257 TRP B CE3 1 
ATOM   1859 C CZ2 . TRP B 2 257 ? 58.694  65.984  52.348 1.00 181.94 ? 257 TRP B CZ2 1 
ATOM   1860 C CZ3 . TRP B 2 257 ? 58.280  66.720  50.103 1.00 167.53 ? 257 TRP B CZ3 1 
ATOM   1861 C CH2 . TRP B 2 257 ? 58.129  66.878  51.458 1.00 158.86 ? 257 TRP B CH2 1 
ATOM   1862 N N   . ASN B 2 258 ? 61.847  65.923  47.984 1.00 173.34 ? 258 ASN B N   1 
ATOM   1863 C CA  . ASN B 2 258 ? 61.525  67.160  47.275 1.00 180.97 ? 258 ASN B CA  1 
ATOM   1864 C C   . ASN B 2 258 ? 62.538  67.501  46.176 1.00 248.03 ? 258 ASN B C   1 
ATOM   1865 O O   . ASN B 2 258 ? 62.219  68.316  45.308 1.00 257.56 ? 258 ASN B O   1 
ATOM   1866 C CB  . ASN B 2 258 ? 61.337  68.324  48.256 1.00 189.09 ? 258 ASN B CB  1 
ATOM   1867 C CG  . ASN B 2 258 ? 62.489  68.567  49.211 1.00 245.62 ? 258 ASN B CG  1 
ATOM   1868 O OD1 . ASN B 2 258 ? 62.958  67.654  49.895 1.00 165.12 ? 258 ASN B OD1 1 
ATOM   1869 N ND2 . ASN B 2 258 ? 62.929  69.814  49.285 1.00 312.50 ? 258 ASN B ND2 1 
ATOM   1870 N N   . TYR B 2 259 ? 63.742  66.894  46.177 1.00 311.92 ? 259 TYR B N   1 
ATOM   1871 C CA  . TYR B 2 259 ? 64.787  67.213  45.201 1.00 315.12 ? 259 TYR B CA  1 
ATOM   1872 C C   . TYR B 2 259 ? 64.766  66.336  43.938 1.00 260.50 ? 259 TYR B C   1 
ATOM   1873 O O   . TYR B 2 259 ? 65.121  66.825  42.858 1.00 322.10 ? 259 TYR B O   1 
ATOM   1874 C CB  . TYR B 2 259 ? 66.172  67.042  45.839 1.00 304.45 ? 259 TYR B CB  1 
ATOM   1875 C CG  . TYR B 2 259 ? 66.524  67.877  47.064 1.00 365.02 ? 259 TYR B CG  1 
ATOM   1876 C CD1 . TYR B 2 259 ? 65.974  69.142  47.295 1.00 420.42 ? 259 TYR B CD1 1 
ATOM   1877 C CD2 . TYR B 2 259 ? 67.427  67.384  48.011 1.00 394.84 ? 259 TYR B CD2 1 
ATOM   1878 C CE1 . TYR B 2 259 ? 66.319  69.879  48.425 1.00 439.47 ? 259 TYR B CE1 1 
ATOM   1879 C CE2 . TYR B 2 259 ? 67.771  68.112  49.143 1.00 414.03 ? 259 TYR B CE2 1 
ATOM   1880 C CZ  . TYR B 2 259 ? 67.215  69.365  49.356 1.00 421.36 ? 259 TYR B CZ  1 
ATOM   1881 O OH  . TYR B 2 259 ? 67.552  70.094  50.470 1.00 340.36 ? 259 TYR B OH  1 
ATOM   1882 N N   . LEU B 2 260 ? 64.408  65.043  44.072 1.00 209.91 ? 260 LEU B N   1 
ATOM   1883 C CA  . LEU B 2 260 ? 64.862  64.002  43.142 1.00 349.16 ? 260 LEU B CA  1 
ATOM   1884 C C   . LEU B 2 260 ? 63.819  62.919  42.831 1.00 319.83 ? 260 LEU B C   1 
ATOM   1885 O O   . LEU B 2 260 ? 64.092  62.050  42.000 1.00 363.19 ? 260 LEU B O   1 
ATOM   1886 C CB  . LEU B 2 260 ? 66.127  63.352  43.731 1.00 428.56 ? 260 LEU B CB  1 
ATOM   1887 C CG  . LEU B 2 260 ? 67.437  64.128  43.557 1.00 460.38 ? 260 LEU B CG  1 
ATOM   1888 C CD1 . LEU B 2 260 ? 68.494  63.636  44.536 1.00 472.32 ? 260 LEU B CD1 1 
ATOM   1889 C CD2 . LEU B 2 260 ? 67.979  64.025  42.136 1.00 464.94 ? 260 LEU B CD2 1 
ATOM   1890 N N   . ASN B 2 261 ? 62.631  62.945  43.447 1.00 227.46 ? 261 ASN B N   1 
ATOM   1891 C CA  . ASN B 2 261 ? 61.716  61.812  43.396 1.00 223.10 ? 261 ASN B CA  1 
ATOM   1892 C C   . ASN B 2 261 ? 61.287  61.449  41.955 1.00 341.80 ? 261 ASN B C   1 
ATOM   1893 O O   . ASN B 2 261 ? 61.102  60.261  41.622 1.00 421.44 ? 261 ASN B O   1 
ATOM   1894 C CB  . ASN B 2 261 ? 60.536  62.157  44.294 1.00 236.62 ? 261 ASN B CB  1 
ATOM   1895 C CG  . ASN B 2 261 ? 59.544  61.036  44.356 1.00 310.65 ? 261 ASN B CG  1 
ATOM   1896 O OD1 . ASN B 2 261 ? 59.854  60.022  44.960 1.00 214.54 ? 261 ASN B OD1 1 
ATOM   1897 N ND2 . ASN B 2 261 ? 58.387  61.216  43.735 1.00 398.30 ? 261 ASN B ND2 1 
ATOM   1898 N N   . PHE B 2 262 ? 61.139  62.485  41.101 1.00 350.55 ? 262 PHE B N   1 
ATOM   1899 C CA  . PHE B 2 262 ? 60.811  62.378  39.678 1.00 289.41 ? 262 PHE B CA  1 
ATOM   1900 C C   . PHE B 2 262 ? 61.798  61.527  38.861 1.00 244.58 ? 262 PHE B C   1 
ATOM   1901 O O   . PHE B 2 262 ? 61.398  61.026  37.813 1.00 248.31 ? 262 PHE B O   1 
ATOM   1902 C CB  . PHE B 2 262 ? 60.692  63.783  39.072 1.00 301.81 ? 262 PHE B CB  1 
ATOM   1903 C CG  . PHE B 2 262 ? 61.898  64.679  39.269 1.00 353.98 ? 262 PHE B CG  1 
ATOM   1904 C CD1 . PHE B 2 262 ? 63.053  64.523  38.505 1.00 301.52 ? 262 PHE B CD1 1 
ATOM   1905 C CD2 . PHE B 2 262 ? 61.885  65.680  40.238 1.00 390.87 ? 262 PHE B CD2 1 
ATOM   1906 C CE1 . PHE B 2 262 ? 64.157  65.350  38.696 1.00 285.39 ? 262 PHE B CE1 1 
ATOM   1907 C CE2 . PHE B 2 262 ? 62.987  66.509  40.432 1.00 377.22 ? 262 PHE B CE2 1 
ATOM   1908 C CZ  . PHE B 2 262 ? 64.126  66.345  39.662 1.00 335.84 ? 262 PHE B CZ  1 
ATOM   1909 N N   . VAL B 2 263 ? 63.063  61.352  39.300 1.00 211.69 ? 263 VAL B N   1 
ATOM   1910 C CA  . VAL B 2 263 ? 64.044  60.496  38.627 1.00 200.97 ? 263 VAL B CA  1 
ATOM   1911 C C   . VAL B 2 263 ? 63.495  59.089  38.342 1.00 196.79 ? 263 VAL B C   1 
ATOM   1912 O O   . VAL B 2 263 ? 63.787  58.522  37.281 1.00 303.37 ? 263 VAL B O   1 
ATOM   1913 C CB  . VAL B 2 263 ? 65.367  60.447  39.421 1.00 227.57 ? 263 VAL B CB  1 
ATOM   1914 C CG1 . VAL B 2 263 ? 66.317  59.318  39.023 1.00 240.58 ? 263 VAL B CG1 1 
ATOM   1915 C CG2 . VAL B 2 263 ? 66.075  61.791  39.295 1.00 298.11 ? 263 VAL B CG2 1 
ATOM   1916 N N   . THR B 2 264 ? 62.695  58.526  39.262 1.00 209.82 ? 264 THR B N   1 
ATOM   1917 C CA  . THR B 2 264 ? 62.154  57.180  39.102 1.00 214.85 ? 264 THR B CA  1 
ATOM   1918 C C   . THR B 2 264 ? 61.180  57.053  37.922 1.00 290.26 ? 264 THR B C   1 
ATOM   1919 O O   . THR B 2 264 ? 61.035  55.938  37.414 1.00 392.41 ? 264 THR B O   1 
ATOM   1920 C CB  . THR B 2 264 ? 61.510  56.667  40.393 1.00 318.91 ? 264 THR B CB  1 
ATOM   1921 O OG1 . THR B 2 264 ? 60.461  57.547  40.787 1.00 304.28 ? 264 THR B OG1 1 
ATOM   1922 C CG2 . THR B 2 264 ? 62.519  56.528  41.515 1.00 398.64 ? 264 THR B CG2 1 
ATOM   1923 N N   . GLU B 2 265 ? 60.544  58.153  37.466 1.00 292.65 ? 265 GLU B N   1 
ATOM   1924 C CA  . GLU B 2 265 ? 59.648  58.137  36.298 1.00 332.27 ? 265 GLU B CA  1 
ATOM   1925 C C   . GLU B 2 265 ? 60.385  57.811  34.978 1.00 290.66 ? 265 GLU B C   1 
ATOM   1926 O O   . GLU B 2 265 ? 59.756  57.343  34.022 1.00 241.64 ? 265 GLU B O   1 
ATOM   1927 C CB  . GLU B 2 265 ? 58.865  59.459  36.261 1.00 331.20 ? 265 GLU B CB  1 
ATOM   1928 C CG  . GLU B 2 265 ? 57.831  59.585  35.138 1.00 393.47 ? 265 GLU B CG  1 
ATOM   1929 C CD  . GLU B 2 265 ? 58.280  60.215  33.824 1.00 412.66 ? 265 GLU B CD  1 
ATOM   1930 O OE1 . GLU B 2 265 ? 59.435  60.660  33.729 1.00 331.49 ? 265 GLU B OE1 1 
ATOM   1931 O OE2 . GLU B 2 265 ? 57.456  60.268  32.881 1.00 479.42 ? 265 GLU B OE2 1 
ATOM   1932 N N   . GLU B 2 266 ? 61.713  58.013  34.910 1.00 266.15 ? 266 GLU B N   1 
ATOM   1933 C CA  . GLU B 2 266 ? 62.506  57.657  33.733 1.00 224.38 ? 266 GLU B CA  1 
ATOM   1934 C C   . GLU B 2 266 ? 62.822  56.149  33.634 1.00 257.83 ? 266 GLU B C   1 
ATOM   1935 O O   . GLU B 2 266 ? 63.452  55.746  32.652 1.00 296.72 ? 266 GLU B O   1 
ATOM   1936 C CB  . GLU B 2 266 ? 63.800  58.474  33.730 1.00 286.23 ? 266 GLU B CB  1 
ATOM   1937 C CG  . GLU B 2 266 ? 63.555  59.981  33.746 1.00 338.66 ? 266 GLU B CG  1 
ATOM   1938 C CD  . GLU B 2 266 ? 64.758  60.880  33.516 1.00 390.59 ? 266 GLU B CD  1 
ATOM   1939 O OE1 . GLU B 2 266 ? 65.848  60.567  34.042 1.00 408.35 ? 266 GLU B OE1 1 
ATOM   1940 O OE2 . GLU B 2 266 ? 64.603  61.909  32.819 1.00 397.72 ? 266 GLU B OE2 1 
ATOM   1941 N N   . MET B 2 267 ? 62.415  55.314  34.619 1.00 331.25 ? 267 MET B N   1 
ATOM   1942 C CA  . MET B 2 267 ? 62.563  53.854  34.571 1.00 387.39 ? 267 MET B CA  1 
ATOM   1943 C C   . MET B 2 267 ? 61.289  53.085  34.982 1.00 358.69 ? 267 MET B C   1 
ATOM   1944 O O   . MET B 2 267 ? 61.148  51.916  34.607 1.00 253.32 ? 267 MET B O   1 
ATOM   1945 C CB  . MET B 2 267 ? 63.729  53.420  35.476 1.00 460.35 ? 267 MET B CB  1 
ATOM   1946 C CG  . MET B 2 267 ? 65.117  53.827  34.968 1.00 473.40 ? 267 MET B CG  1 
ATOM   1947 S SD  . MET B 2 267 ? 65.691  55.480  35.493 1.00 489.01 ? 267 MET B SD  1 
ATOM   1948 C CE  . MET B 2 267 ? 66.008  55.219  37.238 1.00 507.32 ? 267 MET B CE  1 
ATOM   1949 N N   . ILE B 2 268 ? 60.373  53.705  35.759 1.00 434.02 ? 268 ILE B N   1 
ATOM   1950 C CA  . ILE B 2 268 ? 59.043  53.178  36.055 1.00 475.50 ? 268 ILE B CA  1 
ATOM   1951 C C   . ILE B 2 268 ? 58.042  53.903  35.152 1.00 428.92 ? 268 ILE B C   1 
ATOM   1952 O O   . ILE B 2 268 ? 57.716  55.070  35.381 1.00 423.27 ? 268 ILE B O   1 
ATOM   1953 C CB  . ILE B 2 268 ? 58.706  53.343  37.560 1.00 508.69 ? 268 ILE B CB  1 
ATOM   1954 C CG1 . ILE B 2 268 ? 59.724  52.651  38.476 1.00 530.14 ? 268 ILE B CG1 1 
ATOM   1955 C CG2 . ILE B 2 268 ? 57.280  52.895  37.887 1.00 480.65 ? 268 ILE B CG2 1 
ATOM   1956 C CD1 . ILE B 2 268 ? 59.882  51.176  38.246 1.00 515.58 ? 268 ILE B CD1 1 
ATOM   1957 N N   . ASN B 2 269 ? 57.530  53.207  34.125 1.00 374.15 ? 269 ASN B N   1 
ATOM   1958 C CA  . ASN B 2 269 ? 56.890  53.880  32.993 1.00 387.86 ? 269 ASN B CA  1 
ATOM   1959 C C   . ASN B 2 269 ? 55.451  54.343  33.308 1.00 342.03 ? 269 ASN B C   1 
ATOM   1960 O O   . ASN B 2 269 ? 55.140  55.518  33.066 1.00 281.98 ? 269 ASN B O   1 
ATOM   1961 C CB  . ASN B 2 269 ? 56.979  53.037  31.714 1.00 427.36 ? 269 ASN B CB  1 
ATOM   1962 C CG  . ASN B 2 269 ? 58.324  52.354  31.524 1.00 399.30 ? 269 ASN B CG  1 
ATOM   1963 O OD1 . ASN B 2 269 ? 58.532  51.243  32.011 1.00 342.00 ? 269 ASN B OD1 1 
ATOM   1964 N ND2 . ASN B 2 269 ? 59.238  53.002  30.817 1.00 388.14 ? 269 ASN B ND2 1 
ATOM   1965 N N   . PRO B 2 270 ? 54.513  53.496  33.824 1.00 297.38 ? 270 PRO B N   1 
ATOM   1966 C CA  . PRO B 2 270 ? 53.148  53.949  34.106 1.00 276.18 ? 270 PRO B CA  1 
ATOM   1967 C C   . PRO B 2 270 ? 53.064  54.969  35.248 1.00 224.47 ? 270 PRO B C   1 
ATOM   1968 O O   . PRO B 2 270 ? 53.597  54.770  36.327 1.00 199.30 ? 270 PRO B O   1 
ATOM   1969 C CB  . PRO B 2 270 ? 52.388  52.653  34.476 1.00 273.42 ? 270 PRO B CB  1 
ATOM   1970 C CG  . PRO B 2 270 ? 53.282  51.522  33.998 1.00 266.76 ? 270 PRO B CG  1 
ATOM   1971 C CD  . PRO B 2 270 ? 54.682  52.070  34.163 1.00 254.42 ? 270 PRO B CD  1 
ATOM   1972 N N   . TYR B 2 271 ? 52.343  56.072  35.019 1.00 249.22 ? 271 TYR B N   1 
ATOM   1973 C CA  . TYR B 2 271 ? 52.193  57.160  35.988 1.00 232.55 ? 271 TYR B CA  1 
ATOM   1974 C C   . TYR B 2 271 ? 51.496  56.720  37.284 1.00 219.40 ? 271 TYR B C   1 
ATOM   1975 O O   . TYR B 2 271 ? 51.799  57.288  38.322 1.00 246.18 ? 271 TYR B O   1 
ATOM   1976 C CB  . TYR B 2 271 ? 51.479  58.341  35.312 1.00 229.23 ? 271 TYR B CB  1 
ATOM   1977 C CG  . TYR B 2 271 ? 52.421  58.966  34.298 1.00 252.14 ? 271 TYR B CG  1 
ATOM   1978 C CD1 . TYR B 2 271 ? 53.460  59.776  34.727 1.00 305.08 ? 271 TYR B CD1 1 
ATOM   1979 C CD2 . TYR B 2 271 ? 52.307  58.726  32.929 1.00 318.45 ? 271 TYR B CD2 1 
ATOM   1980 C CE1 . TYR B 2 271 ? 54.342  60.352  33.826 1.00 382.07 ? 271 TYR B CE1 1 
ATOM   1981 C CE2 . TYR B 2 271 ? 53.187  59.295  32.017 1.00 359.94 ? 271 TYR B CE2 1 
ATOM   1982 C CZ  . TYR B 2 271 ? 54.211  60.115  32.467 1.00 384.59 ? 271 TYR B CZ  1 
ATOM   1983 O OH  . TYR B 2 271 ? 55.122  60.710  31.628 1.00 425.67 ? 271 TYR B OH  1 
ATOM   1984 N N   . ARG B 2 272 ? 50.610  55.709  37.276 1.00 240.55 ? 272 ARG B N   1 
ATOM   1985 C CA  . ARG B 2 272 ? 50.024  55.195  38.518 1.00 263.53 ? 272 ARG B CA  1 
ATOM   1986 C C   . ARG B 2 272 ? 51.014  54.319  39.315 1.00 273.45 ? 272 ARG B C   1 
ATOM   1987 O O   . ARG B 2 272 ? 50.779  54.092  40.508 1.00 281.43 ? 272 ARG B O   1 
ATOM   1988 C CB  . ARG B 2 272 ? 48.707  54.465  38.210 1.00 343.54 ? 272 ARG B CB  1 
ATOM   1989 C CG  . ARG B 2 272 ? 47.844  54.191  39.437 1.00 396.62 ? 272 ARG B CG  1 
ATOM   1990 C CD  . ARG B 2 272 ? 46.462  53.651  39.123 1.00 419.44 ? 272 ARG B CD  1 
ATOM   1991 N NE  . ARG B 2 272 ? 45.656  53.505  40.336 1.00 406.36 ? 272 ARG B NE  1 
ATOM   1992 C CZ  . ARG B 2 272 ? 45.476  52.375  41.026 1.00 393.68 ? 272 ARG B CZ  1 
ATOM   1993 N NH1 . ARG B 2 272 ? 44.692  52.368  42.092 1.00 361.69 ? 272 ARG B NH1 1 
ATOM   1994 N NH2 . ARG B 2 272 ? 46.072  51.250  40.660 1.00 391.81 ? 272 ARG B NH2 1 
ATOM   1995 N N   . ASN B 2 273 ? 52.118  53.839  38.707 1.00 255.87 ? 273 ASN B N   1 
ATOM   1996 C CA  . ASN B 2 273 ? 53.135  53.061  39.415 1.00 250.44 ? 273 ASN B CA  1 
ATOM   1997 C C   . ASN B 2 273 ? 54.109  53.949  40.219 1.00 204.62 ? 273 ASN B C   1 
ATOM   1998 O O   . ASN B 2 273 ? 54.731  53.453  41.144 1.00 188.88 ? 273 ASN B O   1 
ATOM   1999 C CB  . ASN B 2 273 ? 53.854  52.107  38.452 1.00 304.79 ? 273 ASN B CB  1 
ATOM   2000 C CG  . ASN B 2 273 ? 53.000  50.964  37.917 1.00 340.17 ? 273 ASN B CG  1 
ATOM   2001 O OD1 . ASN B 2 273 ? 51.773  50.950  38.039 1.00 306.07 ? 273 ASN B OD1 1 
ATOM   2002 N ND2 . ASN B 2 273 ? 53.648  49.979  37.310 1.00 330.52 ? 273 ASN B ND2 1 
ATOM   2003 N N   . LEU B 2 274 ? 54.243  55.253  39.928 1.00 239.94 ? 274 LEU B N   1 
ATOM   2004 C CA  . LEU B 2 274 ? 55.067  56.166  40.729 1.00 215.37 ? 274 LEU B CA  1 
ATOM   2005 C C   . LEU B 2 274 ? 54.505  56.342  42.154 1.00 145.98 ? 274 LEU B C   1 
ATOM   2006 O O   . LEU B 2 274 ? 55.263  56.168  43.111 1.00 185.87 ? 274 LEU B O   1 
ATOM   2007 C CB  . LEU B 2 274 ? 55.242  57.500  39.978 1.00 230.35 ? 274 LEU B CB  1 
ATOM   2008 C CG  . LEU B 2 274 ? 55.963  58.615  40.733 1.00 209.82 ? 274 LEU B CG  1 
ATOM   2009 C CD1 . LEU B 2 274 ? 57.394  58.227  40.983 1.00 192.56 ? 274 LEU B CD1 1 
ATOM   2010 C CD2 . LEU B 2 274 ? 55.942  59.905  39.958 1.00 280.52 ? 274 LEU B CD2 1 
ATOM   2011 N N   . PRO B 2 275 ? 53.210  56.652  42.394 1.00 139.09 ? 275 PRO B N   1 
ATOM   2012 C CA  . PRO B 2 275 ? 52.594  56.473  43.719 1.00 209.57 ? 275 PRO B CA  1 
ATOM   2013 C C   . PRO B 2 275 ? 52.816  55.107  44.386 1.00 196.46 ? 275 PRO B C   1 
ATOM   2014 O O   . PRO B 2 275 ? 53.046  55.082  45.579 1.00 181.57 ? 275 PRO B O   1 
ATOM   2015 C CB  . PRO B 2 275 ? 51.097  56.734  43.480 1.00 227.56 ? 275 PRO B CB  1 
ATOM   2016 C CG  . PRO B 2 275 ? 51.110  57.691  42.320 1.00 238.11 ? 275 PRO B CG  1 
ATOM   2017 C CD  . PRO B 2 275 ? 52.253  57.212  41.450 1.00 181.87 ? 275 PRO B CD  1 
ATOM   2018 N N   . LEU B 2 276 ? 52.802  53.982  43.668 1.00 170.89 ? 276 LEU B N   1 
ATOM   2019 C CA  . LEU B 2 276 ? 53.102  52.700  44.306 1.00 192.71 ? 276 LEU B CA  1 
ATOM   2020 C C   . LEU B 2 276 ? 54.558  52.637  44.799 1.00 204.18 ? 276 LEU B C   1 
ATOM   2021 O O   . LEU B 2 276 ? 54.790  52.128  45.890 1.00 191.57 ? 276 LEU B O   1 
ATOM   2022 C CB  . LEU B 2 276 ? 52.781  51.532  43.359 1.00 244.06 ? 276 LEU B CB  1 
ATOM   2023 C CG  . LEU B 2 276 ? 51.293  51.355  43.035 1.00 317.97 ? 276 LEU B CG  1 
ATOM   2024 C CD1 . LEU B 2 276 ? 51.097  50.173  42.097 1.00 404.43 ? 276 LEU B CD1 1 
ATOM   2025 C CD2 . LEU B 2 276 ? 50.423  51.171  44.285 1.00 306.99 ? 276 LEU B CD2 1 
ATOM   2026 N N   . ALA B 2 277 ? 55.540  53.146  44.040 1.00 270.57 ? 277 ALA B N   1 
ATOM   2027 C CA  . ALA B 2 277 ? 56.940  53.199  44.473 1.00 258.50 ? 277 ALA B CA  1 
ATOM   2028 C C   . ALA B 2 277 ? 57.121  54.047  45.739 1.00 179.87 ? 277 ALA B C   1 
ATOM   2029 O O   . ALA B 2 277 ? 57.839  53.666  46.650 1.00 160.51 ? 277 ALA B O   1 
ATOM   2030 C CB  . ALA B 2 277 ? 57.815  53.686  43.334 1.00 283.06 ? 277 ALA B CB  1 
ATOM   2031 N N   . ILE B 2 278 ? 56.445  55.191  45.832 1.00 133.61 ? 278 ILE B N   1 
ATOM   2032 C CA  . ILE B 2 278 ? 56.426  56.007  47.043 1.00 116.97 ? 278 ILE B CA  1 
ATOM   2033 C C   . ILE B 2 278 ? 55.794  55.252  48.219 1.00 146.61 ? 278 ILE B C   1 
ATOM   2034 O O   . ILE B 2 278 ? 56.404  55.151  49.266 1.00 133.19 ? 278 ILE B O   1 
ATOM   2035 C CB  . ILE B 2 278 ? 55.653  57.324  46.756 1.00 134.88 ? 278 ILE B CB  1 
ATOM   2036 C CG1 . ILE B 2 278 ? 56.469  58.230  45.857 1.00 134.72 ? 278 ILE B CG1 1 
ATOM   2037 C CG2 . ILE B 2 278 ? 55.167  58.114  47.980 1.00 143.22 ? 278 ILE B CG2 1 
ATOM   2038 C CD1 . ILE B 2 278 ? 55.592  59.208  45.127 1.00 176.26 ? 278 ILE B CD1 1 
ATOM   2039 N N   . ILE B 2 279 ? 54.557  54.756  48.053 1.00 177.66 ? 279 ILE B N   1 
ATOM   2040 C CA  . ILE B 2 279 ? 53.747  54.181  49.119 1.00 148.86 ? 279 ILE B CA  1 
ATOM   2041 C C   . ILE B 2 279 ? 54.373  52.884  49.618 1.00 131.76 ? 279 ILE B C   1 
ATOM   2042 O O   . ILE B 2 279 ? 54.211  52.571  50.793 1.00 212.35 ? 279 ILE B O   1 
ATOM   2043 C CB  . ILE B 2 279 ? 52.285  54.021  48.642 1.00 204.83 ? 279 ILE B CB  1 
ATOM   2044 C CG1 . ILE B 2 279 ? 51.621  55.383  48.390 1.00 255.76 ? 279 ILE B CG1 1 
ATOM   2045 C CG2 . ILE B 2 279 ? 51.440  53.182  49.602 1.00 254.57 ? 279 ILE B CG2 1 
ATOM   2046 C CD1 . ILE B 2 279 ? 51.272  56.171  49.632 1.00 248.45 ? 279 ILE B CD1 1 
ATOM   2047 N N   . ILE B 2 280 ? 55.087  52.124  48.776 1.00 153.29 ? 280 ILE B N   1 
ATOM   2048 C CA  . ILE B 2 280 ? 55.885  50.987  49.243 1.00 200.62 ? 280 ILE B CA  1 
ATOM   2049 C C   . ILE B 2 280 ? 57.173  51.463  49.927 1.00 227.59 ? 280 ILE B C   1 
ATOM   2050 O O   . ILE B 2 280 ? 57.469  50.971  51.003 1.00 261.52 ? 280 ILE B O   1 
ATOM   2051 C CB  . ILE B 2 280 ? 56.141  49.975  48.110 1.00 234.37 ? 280 ILE B CB  1 
ATOM   2052 C CG1 . ILE B 2 280 ? 54.827  49.314  47.680 1.00 341.38 ? 280 ILE B CG1 1 
ATOM   2053 C CG2 . ILE B 2 280 ? 57.169  48.924  48.517 1.00 254.44 ? 280 ILE B CG2 1 
ATOM   2054 C CD1 . ILE B 2 280 ? 54.902  48.492  46.412 1.00 410.69 ? 280 ILE B CD1 1 
ATOM   2055 N N   . SER B 2 281 ? 57.936  52.399  49.338 1.00 200.89 ? 281 SER B N   1 
ATOM   2056 C CA  . SER B 2 281 ? 59.272  52.753  49.834 1.00 181.69 ? 281 SER B CA  1 
ATOM   2057 C C   . SER B 2 281 ? 59.278  53.505  51.171 1.00 156.07 ? 281 SER B C   1 
ATOM   2058 O O   . SER B 2 281 ? 60.096  53.189  52.019 1.00 146.48 ? 281 SER B O   1 
ATOM   2059 C CB  . SER B 2 281 ? 60.036  53.562  48.821 1.00 198.16 ? 281 SER B CB  1 
ATOM   2060 O OG  . SER B 2 281 ? 61.332  53.943  49.299 1.00 126.04 ? 281 SER B OG  1 
ATOM   2061 N N   . LEU B 2 282 ? 58.410  54.500  51.411 1.00 136.13 ? 282 LEU B N   1 
ATOM   2062 C CA  . LEU B 2 282 ? 58.588  55.316  52.608 1.00 147.67 ? 282 LEU B CA  1 
ATOM   2063 C C   . LEU B 2 282 ? 58.241  54.565  53.900 1.00 153.14 ? 282 LEU B C   1 
ATOM   2064 O O   . LEU B 2 282 ? 58.880  54.835  54.922 1.00 201.75 ? 282 LEU B O   1 
ATOM   2065 C CB  . LEU B 2 282 ? 57.844  56.651  52.459 1.00 132.43 ? 282 LEU B CB  1 
ATOM   2066 C CG  . LEU B 2 282 ? 58.503  57.612  51.471 1.00 156.52 ? 282 LEU B CG  1 
ATOM   2067 C CD1 . LEU B 2 282 ? 57.750  58.881  51.401 1.00 152.67 ? 282 LEU B CD1 1 
ATOM   2068 C CD2 . LEU B 2 282 ? 59.915  57.994  51.825 1.00 156.93 ? 282 LEU B CD2 1 
ATOM   2069 N N   . PRO B 2 283 ? 57.268  53.632  53.971 1.00 146.34 ? 283 PRO B N   1 
ATOM   2070 C CA  . PRO B 2 283 ? 57.225  52.645  55.051 1.00 160.99 ? 283 PRO B CA  1 
ATOM   2071 C C   . PRO B 2 283 ? 58.494  51.817  55.235 1.00 152.55 ? 283 PRO B C   1 
ATOM   2072 O O   . PRO B 2 283 ? 58.808  51.547  56.399 1.00 254.25 ? 283 PRO B O   1 
ATOM   2073 C CB  . PRO B 2 283 ? 56.014  51.774  54.705 1.00 217.18 ? 283 PRO B CB  1 
ATOM   2074 C CG  . PRO B 2 283 ? 55.134  52.719  53.950 1.00 229.00 ? 283 PRO B CG  1 
ATOM   2075 C CD  . PRO B 2 283 ? 56.107  53.514  53.103 1.00 167.74 ? 283 PRO B CD  1 
ATOM   2076 N N   . ILE B 2 284 ? 59.225  51.449  54.164 1.00 106.46 ? 284 ILE B N   1 
ATOM   2077 C CA  . ILE B 2 284 ? 60.508  50.757  54.316 1.00 156.81 ? 284 ILE B CA  1 
ATOM   2078 C C   . ILE B 2 284 ? 61.558  51.671  54.987 1.00 157.62 ? 284 ILE B C   1 
ATOM   2079 O O   . ILE B 2 284 ? 62.278  51.256  55.889 1.00 151.72 ? 284 ILE B O   1 
ATOM   2080 C CB  . ILE B 2 284 ? 61.000  50.113  53.000 1.00 152.04 ? 284 ILE B CB  1 
ATOM   2081 C CG1 . ILE B 2 284 ? 60.017  49.050  52.491 1.00 222.47 ? 284 ILE B CG1 1 
ATOM   2082 C CG2 . ILE B 2 284 ? 62.384  49.506  53.152 1.00 188.50 ? 284 ILE B CG2 1 
ATOM   2083 C CD1 . ILE B 2 284 ? 59.790  47.816  53.382 1.00 271.83 ? 284 ILE B CD1 1 
ATOM   2084 N N   . VAL B 2 285 ? 61.649  52.930  54.585 1.00 156.89 ? 285 VAL B N   1 
ATOM   2085 C CA  . VAL B 2 285 ? 62.512  53.889  55.273 1.00 172.36 ? 285 VAL B CA  1 
ATOM   2086 C C   . VAL B 2 285 ? 62.103  54.014  56.741 1.00 149.35 ? 285 VAL B C   1 
ATOM   2087 O O   . VAL B 2 285 ? 62.936  53.894  57.625 1.00 149.46 ? 285 VAL B O   1 
ATOM   2088 C CB  . VAL B 2 285 ? 62.502  55.273  54.593 1.00 164.34 ? 285 VAL B CB  1 
ATOM   2089 C CG1 . VAL B 2 285 ? 63.345  56.285  55.339 1.00 136.78 ? 285 VAL B CG1 1 
ATOM   2090 C CG2 . VAL B 2 285 ? 62.988  55.166  53.167 1.00 200.57 ? 285 VAL B CG2 1 
ATOM   2091 N N   . THR B 2 286 ? 60.819  54.251  57.008 1.00 107.42 ? 286 THR B N   1 
ATOM   2092 C CA  . THR B 2 286 ? 60.329  54.388  58.369 1.00 125.55 ? 286 THR B CA  1 
ATOM   2093 C C   . THR B 2 286 ? 60.675  53.162  59.219 1.00 136.76 ? 286 THR B C   1 
ATOM   2094 O O   . THR B 2 286 ? 61.043  53.316  60.386 1.00 203.07 ? 286 THR B O   1 
ATOM   2095 C CB  . THR B 2 286 ? 58.810  54.602  58.413 1.00 186.14 ? 286 THR B CB  1 
ATOM   2096 O OG1 . THR B 2 286 ? 58.473  55.693  57.572 1.00 134.17 ? 286 THR B OG1 1 
ATOM   2097 C CG2 . THR B 2 286 ? 58.266  54.900  59.799 1.00 191.90 ? 286 THR B CG2 1 
ATOM   2098 N N   . LEU B 2 287 ? 60.553  51.956  58.653 1.00 135.21 ? 287 LEU B N   1 
ATOM   2099 C CA  . LEU B 2 287 ? 60.936  50.729  59.326 1.00 166.13 ? 287 LEU B CA  1 
ATOM   2100 C C   . LEU B 2 287 ? 62.426  50.777  59.690 1.00 171.40 ? 287 LEU B C   1 
ATOM   2101 O O   . LEU B 2 287 ? 62.753  50.495  60.852 1.00 236.55 ? 287 LEU B O   1 
ATOM   2102 C CB  . LEU B 2 287 ? 60.580  49.535  58.435 1.00 213.76 ? 287 LEU B CB  1 
ATOM   2103 C CG  . LEU B 2 287 ? 61.032  48.168  58.947 1.00 258.24 ? 287 LEU B CG  1 
ATOM   2104 C CD1 . LEU B 2 287 ? 60.235  47.798  60.191 1.00 336.14 ? 287 LEU B CD1 1 
ATOM   2105 C CD2 . LEU B 2 287 ? 60.937  47.098  57.872 1.00 268.41 ? 287 LEU B CD2 1 
ATOM   2106 N N   . VAL B 2 288 ? 63.323  51.137  58.748 1.00 113.45 ? 288 VAL B N   1 
ATOM   2107 C CA  . VAL B 2 288 ? 64.758  51.193  59.022 1.00 160.19 ? 288 VAL B CA  1 
ATOM   2108 C C   . VAL B 2 288 ? 65.074  52.219  60.123 1.00 142.92 ? 288 VAL B C   1 
ATOM   2109 O O   . VAL B 2 288 ? 65.901  51.990  61.012 1.00 126.01 ? 288 VAL B O   1 
ATOM   2110 C CB  . VAL B 2 288 ? 65.549  51.476  57.731 1.00 148.83 ? 288 VAL B CB  1 
ATOM   2111 C CG1 . VAL B 2 288 ? 67.022  51.754  58.016 1.00 152.61 ? 288 VAL B CG1 1 
ATOM   2112 C CG2 . VAL B 2 288 ? 65.441  50.317  56.768 1.00 167.78 ? 288 VAL B CG2 1 
ATOM   2113 N N   . TYR B 2 289 ? 64.434  53.381  60.078 1.00 131.66 ? 289 TYR B N   1 
ATOM   2114 C CA  . TYR B 2 289 ? 64.653  54.408  61.088 1.00 171.92 ? 289 TYR B CA  1 
ATOM   2115 C C   . TYR B 2 289 ? 64.137  54.009  62.462 1.00 132.54 ? 289 TYR B C   1 
ATOM   2116 O O   . TYR B 2 289 ? 64.832  54.224  63.446 1.00 161.95 ? 289 TYR B O   1 
ATOM   2117 C CB  . TYR B 2 289 ? 64.024  55.695  60.565 1.00 201.38 ? 289 TYR B CB  1 
ATOM   2118 C CG  . TYR B 2 289 ? 64.795  56.391  59.449 1.00 156.52 ? 289 TYR B CG  1 
ATOM   2119 C CD1 . TYR B 2 289 ? 66.037  55.942  58.913 1.00 102.10 ? 289 TYR B CD1 1 
ATOM   2120 C CD2 . TYR B 2 289 ? 64.226  57.549  58.949 1.00 108.59 ? 289 TYR B CD2 1 
ATOM   2121 C CE1 . TYR B 2 289 ? 66.673  56.634  57.908 1.00 99.73  ? 289 TYR B CE1 1 
ATOM   2122 C CE2 . TYR B 2 289 ? 64.841  58.251  57.939 1.00 172.23 ? 289 TYR B CE2 1 
ATOM   2123 C CZ  . TYR B 2 289 ? 66.070  57.807  57.442 1.00 178.10 ? 289 TYR B CZ  1 
ATOM   2124 O OH  . TYR B 2 289 ? 66.616  58.587  56.447 1.00 140.85 ? 289 TYR B OH  1 
ATOM   2125 N N   . VAL B 2 290 ? 62.960  53.401  62.534 1.00 139.03 ? 290 VAL B N   1 
ATOM   2126 C CA  . VAL B 2 290 ? 62.497  52.855  63.801 1.00 140.70 ? 290 VAL B CA  1 
ATOM   2127 C C   . VAL B 2 290 ? 63.436  51.744  64.286 1.00 124.05 ? 290 VAL B C   1 
ATOM   2128 O O   . VAL B 2 290 ? 63.814  51.757  65.456 1.00 182.27 ? 290 VAL B O   1 
ATOM   2129 C CB  . VAL B 2 290 ? 61.034  52.416  63.702 1.00 184.63 ? 290 VAL B CB  1 
ATOM   2130 C CG1 . VAL B 2 290 ? 60.587  51.522  64.854 1.00 236.43 ? 290 VAL B CG1 1 
ATOM   2131 C CG2 . VAL B 2 290 ? 60.147  53.640  63.612 1.00 177.68 ? 290 VAL B CG2 1 
ATOM   2132 N N   . LEU B 2 291 ? 63.842  50.802  63.430 1.00 107.11 ? 291 LEU B N   1 
ATOM   2133 C CA  . LEU B 2 291 ? 64.731  49.717  63.849 1.00 155.54 ? 291 LEU B CA  1 
ATOM   2134 C C   . LEU B 2 291 ? 66.109  50.205  64.326 1.00 161.37 ? 291 LEU B C   1 
ATOM   2135 O O   . LEU B 2 291 ? 66.604  49.697  65.335 1.00 229.03 ? 291 LEU B O   1 
ATOM   2136 C CB  . LEU B 2 291 ? 64.864  48.693  62.725 1.00 134.42 ? 291 LEU B CB  1 
ATOM   2137 C CG  . LEU B 2 291 ? 63.620  47.836  62.501 1.00 185.64 ? 291 LEU B CG  1 
ATOM   2138 C CD1 . LEU B 2 291 ? 63.793  47.023  61.230 1.00 254.83 ? 291 LEU B CD1 1 
ATOM   2139 C CD2 . LEU B 2 291 ? 63.349  46.895  63.677 1.00 271.41 ? 291 LEU B CD2 1 
ATOM   2140 N N   . THR B 2 292 ? 66.730  51.179  63.660 1.00 108.82 ? 292 THR B N   1 
ATOM   2141 C CA  . THR B 2 292 ? 67.987  51.737  64.162 1.00 145.12 ? 292 THR B CA  1 
ATOM   2142 C C   . THR B 2 292 ? 67.817  52.419  65.516 1.00 150.05 ? 292 THR B C   1 
ATOM   2143 O O   . THR B 2 292 ? 68.686  52.274  66.371 1.00 219.53 ? 292 THR B O   1 
ATOM   2144 C CB  . THR B 2 292 ? 68.646  52.722  63.203 1.00 148.98 ? 292 THR B CB  1 
ATOM   2145 O OG1 . THR B 2 292 ? 67.649  53.590  62.675 1.00 189.89 ? 292 THR B OG1 1 
ATOM   2146 C CG2 . THR B 2 292 ? 69.304  51.987  62.075 1.00 184.54 ? 292 THR B CG2 1 
ATOM   2147 N N   . ASN B 2 293 ? 66.715  53.124  65.739 1.00 107.72 ? 293 ASN B N   1 
ATOM   2148 C CA  . ASN B 2 293 ? 66.487  53.716  67.045 1.00 131.94 ? 293 ASN B CA  1 
ATOM   2149 C C   . ASN B 2 293 ? 66.265  52.647  68.122 1.00 147.55 ? 293 ASN B C   1 
ATOM   2150 O O   . ASN B 2 293 ? 66.788  52.782  69.223 1.00 142.99 ? 293 ASN B O   1 
ATOM   2151 C CB  . ASN B 2 293 ? 65.369  54.753  66.971 1.00 154.52 ? 293 ASN B CB  1 
ATOM   2152 C CG  . ASN B 2 293 ? 65.909  56.043  66.409 1.00 157.69 ? 293 ASN B CG  1 
ATOM   2153 O OD1 . ASN B 2 293 ? 66.095  56.992  67.156 1.00 142.14 ? 293 ASN B OD1 1 
ATOM   2154 N ND2 . ASN B 2 293 ? 66.166  56.100  65.111 1.00 184.39 ? 293 ASN B ND2 1 
ATOM   2155 N N   . LEU B 2 294 ? 65.532  51.572  67.830 1.00 156.01 ? 294 LEU B N   1 
ATOM   2156 C CA  . LEU B 2 294 ? 65.465  50.427  68.737 1.00 160.94 ? 294 LEU B CA  1 
ATOM   2157 C C   . LEU B 2 294 ? 66.850  49.829  68.995 1.00 149.48 ? 294 LEU B C   1 
ATOM   2158 O O   . LEU B 2 294 ? 67.135  49.469  70.137 1.00 212.37 ? 294 LEU B O   1 
ATOM   2159 C CB  . LEU B 2 294 ? 64.498  49.376  68.183 1.00 155.33 ? 294 LEU B CB  1 
ATOM   2160 C CG  . LEU B 2 294 ? 63.031  49.798  68.231 1.00 196.41 ? 294 LEU B CG  1 
ATOM   2161 C CD1 . LEU B 2 294 ? 62.187  48.815  67.433 1.00 296.54 ? 294 LEU B CD1 1 
ATOM   2162 C CD2 . LEU B 2 294 ? 62.516  49.889  69.659 1.00 211.80 ? 294 LEU B CD2 1 
ATOM   2163 N N   . ALA B 2 295 ? 67.723  49.718  67.984 1.00 124.69 ? 295 ALA B N   1 
ATOM   2164 C CA  . ALA B 2 295 ? 69.092  49.252  68.205 1.00 164.88 ? 295 ALA B CA  1 
ATOM   2165 C C   . ALA B 2 295 ? 69.829  50.131  69.224 1.00 137.29 ? 295 ALA B C   1 
ATOM   2166 O O   . ALA B 2 295 ? 70.467  49.591  70.132 1.00 191.46 ? 295 ALA B O   1 
ATOM   2167 C CB  . ALA B 2 295 ? 69.820  49.124  66.903 1.00 173.04 ? 295 ALA B CB  1 
ATOM   2168 N N   . TYR B 2 296 ? 69.700  51.454  69.146 1.00 122.07 ? 296 TYR B N   1 
ATOM   2169 C CA  . TYR B 2 296 ? 70.238  52.321  70.190 1.00 176.83 ? 296 TYR B CA  1 
ATOM   2170 C C   . TYR B 2 296 ? 69.529  52.109  71.536 1.00 156.63 ? 296 TYR B C   1 
ATOM   2171 O O   . TYR B 2 296 ? 70.189  51.814  72.532 1.00 203.38 ? 296 TYR B O   1 
ATOM   2172 C CB  . TYR B 2 296 ? 70.186  53.801  69.808 1.00 196.21 ? 296 TYR B CB  1 
ATOM   2173 C CG  . TYR B 2 296 ? 70.838  54.151  68.479 1.00 199.14 ? 296 TYR B CG  1 
ATOM   2174 C CD1 . TYR B 2 296 ? 72.091  53.636  68.124 1.00 143.97 ? 296 TYR B CD1 1 
ATOM   2175 C CD2 . TYR B 2 296 ? 70.186  55.003  67.584 1.00 183.10 ? 296 TYR B CD2 1 
ATOM   2176 C CE1 . TYR B 2 296 ? 72.679  53.959  66.919 1.00 122.76 ? 296 TYR B CE1 1 
ATOM   2177 C CE2 . TYR B 2 296 ? 70.762  55.325  66.366 1.00 211.04 ? 296 TYR B CE2 1 
ATOM   2178 C CZ  . TYR B 2 296 ? 72.005  54.796  66.029 1.00 199.61 ? 296 TYR B CZ  1 
ATOM   2179 O OH  . TYR B 2 296 ? 72.531  55.165  64.809 1.00 175.29 ? 296 TYR B OH  1 
ATOM   2180 N N   . PHE B 2 297 ? 68.210  52.232  71.603 1.00 116.58 ? 297 PHE B N   1 
ATOM   2181 C CA  . PHE B 2 297 ? 67.518  52.168  72.889 1.00 193.81 ? 297 PHE B CA  1 
ATOM   2182 C C   . PHE B 2 297 ? 67.616  50.818  73.627 1.00 194.25 ? 297 PHE B C   1 
ATOM   2183 O O   . PHE B 2 297 ? 67.410  50.774  74.844 1.00 210.64 ? 297 PHE B O   1 
ATOM   2184 C CB  . PHE B 2 297 ? 66.046  52.538  72.693 1.00 208.39 ? 297 PHE B CB  1 
ATOM   2185 C CG  . PHE B 2 297 ? 65.788  53.918  72.148 1.00 136.95 ? 297 PHE B CG  1 
ATOM   2186 C CD1 . PHE B 2 297 ? 66.536  55.006  72.568 1.00 137.81 ? 297 PHE B CD1 1 
ATOM   2187 C CD2 . PHE B 2 297 ? 64.767  54.125  71.224 1.00 196.22 ? 297 PHE B CD2 1 
ATOM   2188 C CE1 . PHE B 2 297 ? 66.274  56.271  72.059 1.00 207.49 ? 297 PHE B CE1 1 
ATOM   2189 C CE2 . PHE B 2 297 ? 64.505  55.391  70.719 1.00 233.47 ? 297 PHE B CE2 1 
ATOM   2190 C CZ  . PHE B 2 297 ? 65.264  56.455  71.143 1.00 244.88 ? 297 PHE B CZ  1 
ATOM   2191 N N   . THR B 2 298 ? 67.913  49.723  72.914 1.00 158.85 ? 298 THR B N   1 
ATOM   2192 C CA  . THR B 2 298 ? 68.146  48.424  73.527 1.00 230.14 ? 298 THR B CA  1 
ATOM   2193 C C   . THR B 2 298 ? 69.608  48.233  73.938 1.00 217.84 ? 298 THR B C   1 
ATOM   2194 O O   . THR B 2 298 ? 69.942  47.165  74.460 1.00 322.32 ? 298 THR B O   1 
ATOM   2195 C CB  . THR B 2 298 ? 67.672  47.296  72.600 1.00 308.44 ? 298 THR B CB  1 
ATOM   2196 O OG1 . THR B 2 298 ? 68.350  47.391  71.344 1.00 308.60 ? 298 THR B OG1 1 
ATOM   2197 C CG2 . THR B 2 298 ? 66.169  47.328  72.397 1.00 347.13 ? 298 THR B CG2 1 
ATOM   2198 N N   . THR B 2 299 ? 70.471  49.247  73.731 1.00 148.51 ? 299 THR B N   1 
ATOM   2199 C CA  . THR B 2 299 ? 71.893  49.185  74.076 1.00 203.44 ? 299 THR B CA  1 
ATOM   2200 C C   . THR B 2 299 ? 72.365  50.340  74.974 1.00 217.52 ? 299 THR B C   1 
ATOM   2201 O O   . THR B 2 299 ? 73.284  50.140  75.773 1.00 222.75 ? 299 THR B O   1 
ATOM   2202 C CB  . THR B 2 299 ? 72.731  49.138  72.796 1.00 202.66 ? 299 THR B CB  1 
ATOM   2203 O OG1 . THR B 2 299 ? 72.171  48.167  71.902 1.00 204.35 ? 299 THR B OG1 1 
ATOM   2204 C CG2 . THR B 2 299 ? 74.193  48.802  73.046 1.00 182.37 ? 299 THR B CG2 1 
ATOM   2205 N N   . LEU B 2 300 ? 71.758  51.540  74.848 1.00 199.12 ? 300 LEU B N   1 
ATOM   2206 C CA  . LEU B 2 300 ? 72.235  52.768  75.485 1.00 189.60 ? 300 LEU B CA  1 
ATOM   2207 C C   . LEU B 2 300 ? 71.153  53.424  76.355 1.00 192.30 ? 300 LEU B C   1 
ATOM   2208 O O   . LEU B 2 300 ? 69.960  53.338  76.072 1.00 208.39 ? 300 LEU B O   1 
ATOM   2209 C CB  . LEU B 2 300 ? 72.678  53.761  74.401 1.00 170.57 ? 300 LEU B CB  1 
ATOM   2210 C CG  . LEU B 2 300 ? 73.769  53.299  73.427 1.00 180.05 ? 300 LEU B CG  1 
ATOM   2211 C CD1 . LEU B 2 300 ? 74.027  54.403  72.417 1.00 173.08 ? 300 LEU B CD1 1 
ATOM   2212 C CD2 . LEU B 2 300 ? 75.072  52.907  74.116 1.00 198.38 ? 300 LEU B CD2 1 
ATOM   2213 N N   . SER B 2 301 ? 71.598  54.101  77.423 1.00 200.59 ? 301 SER B N   1 
ATOM   2214 C CA  . SER B 2 301 ? 70.750  54.900  78.302 1.00 208.09 ? 301 SER B CA  1 
ATOM   2215 C C   . SER B 2 301 ? 70.438  56.261  77.693 1.00 155.59 ? 301 SER B C   1 
ATOM   2216 O O   . SER B 2 301 ? 71.268  56.810  76.981 1.00 199.94 ? 301 SER B O   1 
ATOM   2217 C CB  . SER B 2 301 ? 71.425  55.079  79.639 1.00 231.93 ? 301 SER B CB  1 
ATOM   2218 O OG  . SER B 2 301 ? 70.668  55.927  80.487 1.00 266.36 ? 301 SER B OG  1 
ATOM   2219 N N   . THR B 2 302 ? 69.262  56.842  77.986 1.00 146.62 ? 302 THR B N   1 
ATOM   2220 C CA  . THR B 2 302 ? 68.992  58.248  77.671 1.00 183.99 ? 302 THR B CA  1 
ATOM   2221 C C   . THR B 2 302 ? 70.120  59.184  78.150 1.00 177.42 ? 302 THR B C   1 
ATOM   2222 O O   . THR B 2 302 ? 70.519  60.093  77.394 1.00 163.58 ? 302 THR B O   1 
ATOM   2223 C CB  . THR B 2 302 ? 67.646  58.724  78.243 1.00 231.55 ? 302 THR B CB  1 
ATOM   2224 O OG1 . THR B 2 302 ? 66.620  57.791  77.889 1.00 221.90 ? 302 THR B OG1 1 
ATOM   2225 C CG2 . THR B 2 302 ? 67.264  60.114  77.760 1.00 208.64 ? 302 THR B CG2 1 
ATOM   2226 N N   . GLU B 2 303 ? 70.637  58.948  79.360 1.00 170.24 ? 303 GLU B N   1 
ATOM   2227 C CA  . GLU B 2 303 ? 71.717  59.750  79.927 1.00 231.85 ? 303 GLU B CA  1 
ATOM   2228 C C   . GLU B 2 303 ? 73.047  59.601  79.147 1.00 189.80 ? 303 GLU B C   1 
ATOM   2229 O O   . GLU B 2 303 ? 73.939  60.444  79.320 1.00 211.71 ? 303 GLU B O   1 
ATOM   2230 C CB  . GLU B 2 303 ? 71.941  59.401  81.413 1.00 414.04 ? 303 GLU B CB  1 
ATOM   2231 C CG  . GLU B 2 303 ? 70.805  59.674  82.369 1.00 446.93 ? 303 GLU B CG  1 
ATOM   2232 C CD  . GLU B 2 303 ? 71.104  59.586  83.878 1.00 377.25 ? 303 GLU B CD  1 
ATOM   2233 O OE1 . GLU B 2 303 ? 72.203  59.071  84.392 1.00 188.58 ? 303 GLU B OE1 1 
ATOM   2234 O OE2 . GLU B 2 303 ? 70.209  60.049  84.631 1.00 309.80 ? 303 GLU B OE2 1 
ATOM   2235 N N   . GLN B 2 304 ? 73.213  58.546  78.316 1.00 168.73 ? 304 GLN B N   1 
ATOM   2236 C CA  . GLN B 2 304 ? 74.328  58.413  77.397 1.00 200.47 ? 304 GLN B CA  1 
ATOM   2237 C C   . GLN B 2 304 ? 74.017  59.098  76.066 1.00 185.33 ? 304 GLN B C   1 
ATOM   2238 O O   . GLN B 2 304 ? 74.814  59.899  75.595 1.00 203.98 ? 304 GLN B O   1 
ATOM   2239 C CB  . GLN B 2 304 ? 74.666  56.944  77.157 1.00 208.07 ? 304 GLN B CB  1 
ATOM   2240 C CG  . GLN B 2 304 ? 75.240  56.235  78.369 1.00 263.71 ? 304 GLN B CG  1 
ATOM   2241 C CD  . GLN B 2 304 ? 75.409  54.756  78.108 1.00 323.83 ? 304 GLN B CD  1 
ATOM   2242 O OE1 . GLN B 2 304 ? 74.436  54.005  78.073 1.00 309.57 ? 304 GLN B OE1 1 
ATOM   2243 N NE2 . GLN B 2 304 ? 76.646  54.316  77.923 1.00 378.74 ? 304 GLN B NE2 1 
ATOM   2244 N N   . MET B 2 305 ? 72.863  58.807  75.457 1.00 187.15 ? 305 MET B N   1 
ATOM   2245 C CA  . MET B 2 305 ? 72.546  59.242  74.102 1.00 163.06 ? 305 MET B CA  1 
ATOM   2246 C C   . MET B 2 305 ? 72.447  60.762  73.972 1.00 161.09 ? 305 MET B C   1 
ATOM   2247 O O   . MET B 2 305 ? 72.649  61.275  72.865 1.00 225.14 ? 305 MET B O   1 
ATOM   2248 C CB  . MET B 2 305 ? 71.203  58.648  73.665 1.00 167.88 ? 305 MET B CB  1 
ATOM   2249 C CG  . MET B 2 305 ? 71.287  57.173  73.330 1.00 177.29 ? 305 MET B CG  1 
ATOM   2250 S SD  . MET B 2 305 ? 69.748  56.547  72.597 1.00 214.42 ? 305 MET B SD  1 
ATOM   2251 C CE  . MET B 2 305 ? 69.666  57.374  71.006 1.00 222.15 ? 305 MET B CE  1 
ATOM   2252 N N   . LEU B 2 306 ? 72.100  61.480  75.060 1.00 124.97 ? 306 LEU B N   1 
ATOM   2253 C CA  . LEU B 2 306 ? 72.082  62.937  75.025 1.00 157.67 ? 306 LEU B CA  1 
ATOM   2254 C C   . LEU B 2 306 ? 73.482  63.547  75.198 1.00 176.90 ? 306 LEU B C   1 
ATOM   2255 O O   . LEU B 2 306 ? 73.666  64.728  74.882 1.00 190.14 ? 306 LEU B O   1 
ATOM   2256 C CB  . LEU B 2 306 ? 71.105  63.451  76.085 1.00 188.92 ? 306 LEU B CB  1 
ATOM   2257 C CG  . LEU B 2 306 ? 69.642  63.045  75.874 1.00 220.41 ? 306 LEU B CG  1 
ATOM   2258 C CD1 . LEU B 2 306 ? 68.746  63.704  76.920 1.00 291.77 ? 306 LEU B CD1 1 
ATOM   2259 C CD2 . LEU B 2 306 ? 69.146  63.387  74.466 1.00 161.29 ? 306 LEU B CD2 1 
ATOM   2260 N N   . SER B 2 307 ? 74.463  62.771  75.681 1.00 183.76 ? 307 SER B N   1 
ATOM   2261 C CA  . SER B 2 307 ? 75.800  63.273  75.985 1.00 261.41 ? 307 SER B CA  1 
ATOM   2262 C C   . SER B 2 307 ? 76.746  63.228  74.784 1.00 253.57 ? 307 SER B C   1 
ATOM   2263 O O   . SER B 2 307 ? 77.704  64.001  74.763 1.00 301.90 ? 307 SER B O   1 
ATOM   2264 C CB  . SER B 2 307 ? 76.412  62.523  77.156 1.00 324.84 ? 307 SER B CB  1 
ATOM   2265 O OG  . SER B 2 307 ? 76.875  61.229  76.787 1.00 301.40 ? 307 SER B OG  1 
ATOM   2266 N N   . SER B 2 308 ? 76.492  62.329  73.812 1.00 223.44 ? 308 SER B N   1 
ATOM   2267 C CA  . SER B 2 308 ? 77.402  62.032  72.712 1.00 227.51 ? 308 SER B CA  1 
ATOM   2268 C C   . SER B 2 308 ? 76.959  62.702  71.412 1.00 189.57 ? 308 SER B C   1 
ATOM   2269 O O   . SER B 2 308 ? 75.839  62.474  70.988 1.00 190.04 ? 308 SER B O   1 
ATOM   2270 C CB  . SER B 2 308 ? 77.516  60.545  72.506 1.00 161.12 ? 308 SER B CB  1 
ATOM   2271 O OG  . SER B 2 308 ? 78.526  60.258  71.521 1.00 135.23 ? 308 SER B OG  1 
ATOM   2272 N N   . GLU B 2 309 ? 77.862  63.479  70.784 1.00 194.22 ? 309 GLU B N   1 
ATOM   2273 C CA  . GLU B 2 309 ? 77.638  64.082  69.483 1.00 206.74 ? 309 GLU B CA  1 
ATOM   2274 C C   . GLU B 2 309 ? 77.640  63.055  68.330 1.00 218.36 ? 309 GLU B C   1 
ATOM   2275 O O   . GLU B 2 309 ? 77.301  63.437  67.206 1.00 275.56 ? 309 GLU B O   1 
ATOM   2276 C CB  . GLU B 2 309 ? 78.670  65.196  69.252 1.00 292.04 ? 309 GLU B CB  1 
ATOM   2277 C CG  . GLU B 2 309 ? 80.146  64.776  69.289 1.00 288.21 ? 309 GLU B CG  1 
ATOM   2278 C CD  . GLU B 2 309 ? 80.834  64.734  70.647 1.00 293.09 ? 309 GLU B CD  1 
ATOM   2279 O OE1 . GLU B 2 309 ? 80.149  64.959  71.677 1.00 406.78 ? 309 GLU B OE1 1 
ATOM   2280 O OE2 . GLU B 2 309 ? 82.064  64.463  70.690 1.00 322.48 ? 309 GLU B OE2 1 
ATOM   2281 N N   . ALA B 2 310 ? 78.011  61.779  68.565 1.00 160.57 ? 310 ALA B N   1 
ATOM   2282 C CA  . ALA B 2 310 ? 78.123  60.763  67.525 1.00 163.26 ? 310 ALA B CA  1 
ATOM   2283 C C   . ALA B 2 310 ? 77.618  59.393  68.006 1.00 134.27 ? 310 ALA B C   1 
ATOM   2284 O O   . ALA B 2 310 ? 78.405  58.461  68.154 1.00 106.43 ? 310 ALA B O   1 
ATOM   2285 C CB  . ALA B 2 310 ? 79.576  60.738  67.109 1.00 129.52 ? 310 ALA B CB  1 
ATOM   2286 N N   . VAL B 2 311 ? 76.297  59.274  68.227 1.00 116.11 ? 311 VAL B N   1 
ATOM   2287 C CA  . VAL B 2 311 ? 75.724  58.212  69.063 1.00 121.55 ? 311 VAL B CA  1 
ATOM   2288 C C   . VAL B 2 311 ? 76.051  56.796  68.570 1.00 97.17  ? 311 VAL B C   1 
ATOM   2289 O O   . VAL B 2 311 ? 76.238  55.887  69.367 1.00 118.15 ? 311 VAL B O   1 
ATOM   2290 C CB  . VAL B 2 311 ? 74.206  58.409  69.262 1.00 136.81 ? 311 VAL B CB  1 
ATOM   2291 C CG1 . VAL B 2 311 ? 73.400  58.122  68.033 1.00 155.10 ? 311 VAL B CG1 1 
ATOM   2292 C CG2 . VAL B 2 311 ? 73.667  57.584  70.411 1.00 187.42 ? 311 VAL B CG2 1 
ATOM   2293 N N   . ALA B 2 312 ? 76.131  56.594  67.269 1.00 134.62 ? 312 ALA B N   1 
ATOM   2294 C CA  . ALA B 2 312 ? 76.440  55.280  66.731 1.00 141.37 ? 312 ALA B CA  1 
ATOM   2295 C C   . ALA B 2 312 ? 77.867  54.836  67.062 1.00 115.53 ? 312 ALA B C   1 
ATOM   2296 O O   . ALA B 2 312 ? 78.125  53.637  67.046 1.00 176.16 ? 312 ALA B O   1 
ATOM   2297 C CB  . ALA B 2 312 ? 76.151  55.267  65.244 1.00 160.77 ? 312 ALA B CB  1 
ATOM   2298 N N   . VAL B 2 313 ? 78.795  55.748  67.371 1.00 115.06 ? 313 VAL B N   1 
ATOM   2299 C CA  . VAL B 2 313 ? 80.129  55.357  67.808 1.00 122.11 ? 313 VAL B CA  1 
ATOM   2300 C C   . VAL B 2 313 ? 80.045  54.846  69.245 1.00 136.43 ? 313 VAL B C   1 
ATOM   2301 O O   . VAL B 2 313 ? 80.759  53.901  69.556 1.00 182.72 ? 313 VAL B O   1 
ATOM   2302 C CB  . VAL B 2 313 ? 81.153  56.504  67.670 1.00 159.08 ? 313 VAL B CB  1 
ATOM   2303 C CG1 . VAL B 2 313 ? 82.546  56.133  68.133 1.00 155.86 ? 313 VAL B CG1 1 
ATOM   2304 C CG2 . VAL B 2 313 ? 81.248  56.983  66.250 1.00 178.69 ? 313 VAL B CG2 1 
ATOM   2305 N N   . ASP B 2 314 ? 79.196  55.417  70.126 1.00 140.60 ? 314 ASP B N   1 
ATOM   2306 C CA  . ASP B 2 314 ? 78.970  54.846  71.459 1.00 198.31 ? 314 ASP B CA  1 
ATOM   2307 C C   . ASP B 2 314 ? 78.484  53.387  71.372 1.00 172.37 ? 314 ASP B C   1 
ATOM   2308 O O   . ASP B 2 314 ? 79.026  52.486  72.031 1.00 168.87 ? 314 ASP B O   1 
ATOM   2309 C CB  . ASP B 2 314 ? 77.975  55.661  72.304 1.00 193.18 ? 314 ASP B CB  1 
ATOM   2310 C CG  . ASP B 2 314 ? 78.427  57.051  72.733 1.00 270.41 ? 314 ASP B CG  1 
ATOM   2311 O OD1 . ASP B 2 314 ? 79.137  57.736  71.951 1.00 257.65 ? 314 ASP B OD1 1 
ATOM   2312 O OD2 . ASP B 2 314 ? 78.050  57.476  73.857 1.00 335.23 ? 314 ASP B OD2 1 
ATOM   2313 N N   . PHE B 2 315 ? 77.456  53.163  70.555 1.00 113.76 ? 315 PHE B N   1 
ATOM   2314 C CA  . PHE B 2 315 ? 76.904  51.845  70.280 1.00 121.44 ? 315 PHE B CA  1 
ATOM   2315 C C   . PHE B 2 315 ? 77.971  50.909  69.689 1.00 107.10 ? 315 PHE B C   1 
ATOM   2316 O O   . PHE B 2 315 ? 78.110  49.786  70.113 1.00 158.22 ? 315 PHE B O   1 
ATOM   2317 C CB  . PHE B 2 315 ? 75.691  52.061  69.374 1.00 153.82 ? 315 PHE B CB  1 
ATOM   2318 C CG  . PHE B 2 315 ? 75.063  50.842  68.754 1.00 144.02 ? 315 PHE B CG  1 
ATOM   2319 C CD1 . PHE B 2 315 ? 75.567  50.270  67.595 1.00 146.99 ? 315 PHE B CD1 1 
ATOM   2320 C CD2 . PHE B 2 315 ? 73.958  50.280  69.334 1.00 127.94 ? 315 PHE B CD2 1 
ATOM   2321 C CE1 . PHE B 2 315 ? 74.964  49.169  67.029 1.00 184.02 ? 315 PHE B CE1 1 
ATOM   2322 C CE2 . PHE B 2 315 ? 73.367  49.160  68.779 1.00 164.20 ? 315 PHE B CE2 1 
ATOM   2323 C CZ  . PHE B 2 315 ? 73.866  48.610  67.635 1.00 207.14 ? 315 PHE B CZ  1 
ATOM   2324 N N   . GLY B 2 316 ? 78.755  51.366  68.722 1.00 120.08 ? 316 GLY B N   1 
ATOM   2325 C CA  . GLY B 2 316 ? 79.846  50.595  68.153 1.00 149.31 ? 316 GLY B CA  1 
ATOM   2326 C C   . GLY B 2 316 ? 80.957  50.270  69.150 1.00 182.00 ? 316 GLY B C   1 
ATOM   2327 O O   . GLY B 2 316 ? 81.500  49.170  69.099 1.00 280.32 ? 316 GLY B O   1 
ATOM   2328 N N   . ASN B 2 317 ? 81.273  51.197  70.063 1.00 150.67 ? 317 ASN B N   1 
ATOM   2329 C CA  . ASN B 2 317 ? 82.241  50.978  71.131 1.00 193.91 ? 317 ASN B CA  1 
ATOM   2330 C C   . ASN B 2 317 ? 81.759  49.932  72.148 1.00 200.91 ? 317 ASN B C   1 
ATOM   2331 O O   . ASN B 2 317 ? 82.597  49.246  72.747 1.00 247.48 ? 317 ASN B O   1 
ATOM   2332 C CB  . ASN B 2 317 ? 82.574  52.288  71.856 1.00 216.67 ? 317 ASN B CB  1 
ATOM   2333 C CG  . ASN B 2 317 ? 83.392  53.292  71.061 1.00 283.30 ? 317 ASN B CG  1 
ATOM   2334 O OD1 . ASN B 2 317 ? 83.807  53.052  69.928 1.00 258.73 ? 317 ASN B OD1 1 
ATOM   2335 N ND2 . ASN B 2 317 ? 83.640  54.445  71.664 1.00 342.78 ? 317 ASN B ND2 1 
ATOM   2336 N N   . TYR B 2 318 ? 80.438  49.803  72.354 1.00 172.85 ? 318 TYR B N   1 
ATOM   2337 C CA  . TYR B 2 318 ? 79.888  48.787  73.249 1.00 201.00 ? 318 TYR B CA  1 
ATOM   2338 C C   . TYR B 2 318 ? 80.035  47.368  72.667 1.00 177.71 ? 318 TYR B C   1 
ATOM   2339 O O   . TYR B 2 318 ? 80.583  46.498  73.342 1.00 219.67 ? 318 TYR B O   1 
ATOM   2340 C CB  . TYR B 2 318 ? 78.435  49.138  73.592 1.00 246.30 ? 318 TYR B CB  1 
ATOM   2341 C CG  . TYR B 2 318 ? 77.822  48.173  74.593 1.00 267.38 ? 318 TYR B CG  1 
ATOM   2342 C CD1 . TYR B 2 318 ? 77.217  46.989  74.184 1.00 271.78 ? 318 TYR B CD1 1 
ATOM   2343 C CD2 . TYR B 2 318 ? 77.871  48.440  75.955 1.00 318.06 ? 318 TYR B CD2 1 
ATOM   2344 C CE1 . TYR B 2 318 ? 76.668  46.104  75.102 1.00 298.60 ? 318 TYR B CE1 1 
ATOM   2345 C CE2 . TYR B 2 318 ? 77.323  47.564  76.883 1.00 352.03 ? 318 TYR B CE2 1 
ATOM   2346 C CZ  . TYR B 2 318 ? 76.719  46.391  76.457 1.00 351.00 ? 318 TYR B CZ  1 
ATOM   2347 O OH  . TYR B 2 318 ? 76.176  45.521  77.368 1.00 426.53 ? 318 TYR B OH  1 
ATOM   2348 N N   . HIS B 2 319 ? 79.551  47.123  71.440 1.00 175.84 ? 319 HIS B N   1 
ATOM   2349 C CA  . HIS B 2 319 ? 79.442  45.784  70.870 1.00 195.64 ? 319 HIS B CA  1 
ATOM   2350 C C   . HIS B 2 319 ? 80.729  45.216  70.258 1.00 210.28 ? 319 HIS B C   1 
ATOM   2351 O O   . HIS B 2 319 ? 80.976  44.017  70.407 1.00 287.15 ? 319 HIS B O   1 
ATOM   2352 C CB  . HIS B 2 319 ? 78.330  45.734  69.810 1.00 183.10 ? 319 HIS B CB  1 
ATOM   2353 C CG  . HIS B 2 319 ? 76.957  45.692  70.405 1.00 203.74 ? 319 HIS B CG  1 
ATOM   2354 N ND1 . HIS B 2 319 ? 75.876  46.477  70.072 1.00 157.68 ? 319 HIS B ND1 1 
ATOM   2355 C CD2 . HIS B 2 319 ? 76.513  44.858  71.362 1.00 269.64 ? 319 HIS B CD2 1 
ATOM   2356 C CE1 . HIS B 2 319 ? 74.838  46.125  70.811 1.00 223.20 ? 319 HIS B CE1 1 
ATOM   2357 N NE2 . HIS B 2 319 ? 75.197  45.148  71.601 1.00 275.31 ? 319 HIS B NE2 1 
ATOM   2358 N N   . LEU B 2 320 ? 81.543  46.019  69.555 1.00 189.93 ? 320 LEU B N   1 
ATOM   2359 C CA  . LEU B 2 320 ? 82.383  45.448  68.500 1.00 225.59 ? 320 LEU B CA  1 
ATOM   2360 C C   . LEU B 2 320 ? 83.793  45.070  68.963 1.00 254.03 ? 320 LEU B C   1 
ATOM   2361 O O   . LEU B 2 320 ? 84.337  44.087  68.442 1.00 313.07 ? 320 LEU B O   1 
ATOM   2362 C CB  . LEU B 2 320 ? 82.448  46.410  67.315 1.00 237.92 ? 320 LEU B CB  1 
ATOM   2363 C CG  . LEU B 2 320 ? 81.122  46.617  66.584 1.00 258.01 ? 320 LEU B CG  1 
ATOM   2364 C CD1 . LEU B 2 320 ? 81.237  47.736  65.569 1.00 279.88 ? 320 LEU B CD1 1 
ATOM   2365 C CD2 . LEU B 2 320 ? 80.665  45.335  65.908 1.00 258.04 ? 320 LEU B CD2 1 
ATOM   2366 N N   . GLY B 2 321 ? 84.404  45.813  69.900 1.00 226.42 ? 321 GLY B N   1 
ATOM   2367 C CA  . GLY B 2 321 ? 85.811  45.599  70.256 1.00 256.39 ? 321 GLY B CA  1 
ATOM   2368 C C   . GLY B 2 321 ? 86.812  46.072  69.183 1.00 269.75 ? 321 GLY B C   1 
ATOM   2369 O O   . GLY B 2 321 ? 87.783  46.747  69.509 1.00 246.56 ? 321 GLY B O   1 
ATOM   2370 N N   . VAL B 2 322 ? 86.569  45.724  67.904 1.00 289.10 ? 322 VAL B N   1 
ATOM   2371 C CA  . VAL B 2 322 ? 87.212  46.305  66.718 1.00 291.85 ? 322 VAL B CA  1 
ATOM   2372 C C   . VAL B 2 322 ? 86.622  47.676  66.326 1.00 271.47 ? 322 VAL B C   1 
ATOM   2373 O O   . VAL B 2 322 ? 86.870  48.168  65.216 1.00 231.75 ? 322 VAL B O   1 
ATOM   2374 C CB  . VAL B 2 322 ? 87.141  45.284  65.554 1.00 293.64 ? 322 VAL B CB  1 
ATOM   2375 C CG1 . VAL B 2 322 ? 85.714  45.059  65.026 1.00 224.93 ? 322 VAL B CG1 1 
ATOM   2376 C CG2 . VAL B 2 322 ? 88.100  45.616  64.405 1.00 300.62 ? 322 VAL B CG2 1 
ATOM   2377 N N   . MET B 2 323 ? 85.874  48.312  67.247 1.00 272.62 ? 323 MET B N   1 
ATOM   2378 C CA  . MET B 2 323 ? 85.002  49.472  67.055 1.00 219.94 ? 323 MET B CA  1 
ATOM   2379 C C   . MET B 2 323 ? 85.573  50.533  66.100 1.00 177.27 ? 323 MET B C   1 
ATOM   2380 O O   . MET B 2 323 ? 84.847  50.993  65.224 1.00 132.75 ? 323 MET B O   1 
ATOM   2381 C CB  . MET B 2 323 ? 84.694  50.097  68.435 1.00 276.27 ? 323 MET B CB  1 
ATOM   2382 C CG  . MET B 2 323 ? 85.948  50.570  69.219 1.00 391.50 ? 323 MET B CG  1 
ATOM   2383 S SD  . MET B 2 323 ? 85.802  50.802  71.012 1.00 497.60 ? 323 MET B SD  1 
ATOM   2384 C CE  . MET B 2 323 ? 85.858  49.107  71.585 1.00 535.17 ? 323 MET B CE  1 
ATOM   2385 N N   . SER B 2 324 ? 86.856  50.923  66.242 1.00 216.44 ? 324 SER B N   1 
ATOM   2386 C CA  . SER B 2 324 ? 87.454  52.048  65.522 1.00 312.57 ? 324 SER B CA  1 
ATOM   2387 C C   . SER B 2 324 ? 87.392  51.889  63.997 1.00 250.78 ? 324 SER B C   1 
ATOM   2388 O O   . SER B 2 324 ? 87.244  52.890  63.274 1.00 238.87 ? 324 SER B O   1 
ATOM   2389 C CB  . SER B 2 324 ? 88.888  52.289  65.969 1.00 337.53 ? 324 SER B CB  1 
ATOM   2390 O OG  . SER B 2 324 ? 89.390  53.504  65.405 1.00 282.30 ? 324 SER B OG  1 
ATOM   2391 N N   . TRP B 2 325 ? 87.498  50.642  63.517 1.00 204.25 ? 325 TRP B N   1 
ATOM   2392 C CA  . TRP B 2 325 ? 87.581  50.349  62.087 1.00 261.17 ? 325 TRP B CA  1 
ATOM   2393 C C   . TRP B 2 325 ? 86.222  50.073  61.429 1.00 253.47 ? 325 TRP B C   1 
ATOM   2394 O O   . TRP B 2 325 ? 86.194  49.779  60.229 1.00 279.56 ? 325 TRP B O   1 
ATOM   2395 C CB  . TRP B 2 325 ? 88.554  49.177  61.883 1.00 243.13 ? 325 TRP B CB  1 
ATOM   2396 C CG  . TRP B 2 325 ? 89.969  49.556  62.225 1.00 283.61 ? 325 TRP B CG  1 
ATOM   2397 C CD1 . TRP B 2 325 ? 90.633  49.257  63.378 1.00 311.57 ? 325 TRP B CD1 1 
ATOM   2398 C CD2 . TRP B 2 325 ? 90.900  50.320  61.409 1.00 341.47 ? 325 TRP B CD2 1 
ATOM   2399 N NE1 . TRP B 2 325 ? 91.903  49.777  63.338 1.00 353.45 ? 325 TRP B NE1 1 
ATOM   2400 C CE2 . TRP B 2 325 ? 92.106  50.436  62.146 1.00 373.92 ? 325 TRP B CE2 1 
ATOM   2401 C CE3 . TRP B 2 325 ? 90.847  50.918  60.134 1.00 314.62 ? 325 TRP B CE3 1 
ATOM   2402 C CZ2 . TRP B 2 325 ? 93.229  51.122  61.645 1.00 363.04 ? 325 TRP B CZ2 1 
ATOM   2403 C CZ3 . TRP B 2 325 ? 91.952  51.594  59.640 1.00 292.61 ? 325 TRP B CZ3 1 
ATOM   2404 C CH2 . TRP B 2 325 ? 93.129  51.695  60.390 1.00 317.55 ? 325 TRP B CH2 1 
ATOM   2405 N N   . ILE B 2 326 ? 85.107  50.166  62.188 1.00 166.31 ? 326 ILE B N   1 
ATOM   2406 C CA  . ILE B 2 326 ? 83.797  49.791  61.673 1.00 184.11 ? 326 ILE B CA  1 
ATOM   2407 C C   . ILE B 2 326 ? 82.864  51.013  61.641 1.00 190.24 ? 326 ILE B C   1 
ATOM   2408 O O   . ILE B 2 326 ? 82.807  51.682  60.609 1.00 266.45 ? 326 ILE B O   1 
ATOM   2409 C CB  . ILE B 2 326 ? 83.235  48.575  62.431 1.00 222.91 ? 326 ILE B CB  1 
ATOM   2410 C CG1 . ILE B 2 326 ? 84.186  47.370  62.396 1.00 327.08 ? 326 ILE B CG1 1 
ATOM   2411 C CG2 . ILE B 2 326 ? 81.871  48.189  61.898 1.00 223.62 ? 326 ILE B CG2 1 
ATOM   2412 C CD1 . ILE B 2 326 ? 84.436  46.760  61.013 1.00 335.54 ? 326 ILE B CD1 1 
ATOM   2413 N N   . ILE B 2 327 ? 82.137  51.338  62.725 1.00 139.81 ? 327 ILE B N   1 
ATOM   2414 C CA  . ILE B 2 327 ? 81.066  52.323  62.612 1.00 162.87 ? 327 ILE B CA  1 
ATOM   2415 C C   . ILE B 2 327 ? 81.629  53.698  62.209 1.00 157.80 ? 327 ILE B C   1 
ATOM   2416 O O   . ILE B 2 327 ? 81.068  54.341  61.313 1.00 150.20 ? 327 ILE B O   1 
ATOM   2417 C CB  . ILE B 2 327 ? 80.158  52.369  63.867 1.00 146.85 ? 327 ILE B CB  1 
ATOM   2418 C CG1 . ILE B 2 327 ? 79.516  51.013  64.160 1.00 153.91 ? 327 ILE B CG1 1 
ATOM   2419 C CG2 . ILE B 2 327 ? 79.071  53.421  63.714 1.00 120.52 ? 327 ILE B CG2 1 
ATOM   2420 C CD1 . ILE B 2 327 ? 78.541  50.528  63.114 1.00 152.22 ? 327 ILE B CD1 1 
ATOM   2421 N N   . PRO B 2 328 ? 82.731  54.205  62.806 1.00 150.03 ? 328 PRO B N   1 
ATOM   2422 C CA  . PRO B 2 328 ? 83.324  55.470  62.374 1.00 129.86 ? 328 PRO B CA  1 
ATOM   2423 C C   . PRO B 2 328 ? 83.709  55.506  60.905 1.00 158.88 ? 328 PRO B C   1 
ATOM   2424 O O   . PRO B 2 328 ? 83.542  56.555  60.277 1.00 239.54 ? 328 PRO B O   1 
ATOM   2425 C CB  . PRO B 2 328 ? 84.594  55.589  63.229 1.00 197.73 ? 328 PRO B CB  1 
ATOM   2426 C CG  . PRO B 2 328 ? 84.261  54.758  64.466 1.00 263.32 ? 328 PRO B CG  1 
ATOM   2427 C CD  . PRO B 2 328 ? 83.455  53.606  63.929 1.00 183.08 ? 328 PRO B CD  1 
ATOM   2428 N N   . VAL B 2 329 ? 84.212  54.383  60.355 1.00 174.29 ? 329 VAL B N   1 
ATOM   2429 C CA  . VAL B 2 329 ? 84.630  54.307  58.957 1.00 190.59 ? 329 VAL B CA  1 
ATOM   2430 C C   . VAL B 2 329 ? 83.411  54.266  58.040 1.00 147.07 ? 329 VAL B C   1 
ATOM   2431 O O   . VAL B 2 329 ? 83.310  55.120  57.168 1.00 129.81 ? 329 VAL B O   1 
ATOM   2432 C CB  . VAL B 2 329 ? 85.580  53.120  58.711 1.00 207.63 ? 329 VAL B CB  1 
ATOM   2433 C CG1 . VAL B 2 329 ? 85.801  52.822  57.234 1.00 165.92 ? 329 VAL B CG1 1 
ATOM   2434 C CG2 . VAL B 2 329 ? 86.899  53.373  59.414 1.00 307.01 ? 329 VAL B CG2 1 
ATOM   2435 N N   . PHE B 2 330 ? 82.498  53.304  58.231 1.00 138.81 ? 330 PHE B N   1 
ATOM   2436 C CA  . PHE B 2 330 ? 81.370  53.113  57.331 1.00 158.14 ? 330 PHE B CA  1 
ATOM   2437 C C   . PHE B 2 330 ? 80.418  54.309  57.405 1.00 124.62 ? 330 PHE B C   1 
ATOM   2438 O O   . PHE B 2 330 ? 79.907  54.730  56.361 1.00 174.66 ? 330 PHE B O   1 
ATOM   2439 C CB  . PHE B 2 330 ? 80.711  51.738  57.554 1.00 149.63 ? 330 PHE B CB  1 
ATOM   2440 C CG  . PHE B 2 330 ? 81.645  50.583  57.248 1.00 201.41 ? 330 PHE B CG  1 
ATOM   2441 C CD1 . PHE B 2 330 ? 82.297  50.477  56.015 1.00 195.56 ? 330 PHE B CD1 1 
ATOM   2442 C CD2 . PHE B 2 330 ? 81.903  49.598  58.201 1.00 289.45 ? 330 PHE B CD2 1 
ATOM   2443 C CE1 . PHE B 2 330 ? 83.167  49.427  55.745 1.00 232.57 ? 330 PHE B CE1 1 
ATOM   2444 C CE2 . PHE B 2 330 ? 82.772  48.543  57.930 1.00 332.99 ? 330 PHE B CE2 1 
ATOM   2445 C CZ  . PHE B 2 330 ? 83.402  48.459  56.702 1.00 309.84 ? 330 PHE B CZ  1 
ATOM   2446 N N   . VAL B 2 331 ? 80.152  54.880  58.587 1.00 122.17 ? 331 VAL B N   1 
ATOM   2447 C CA  . VAL B 2 331 ? 79.312  56.079  58.661 1.00 133.41 ? 331 VAL B CA  1 
ATOM   2448 C C   . VAL B 2 331 ? 80.049  57.289  58.077 1.00 118.32 ? 331 VAL B C   1 
ATOM   2449 O O   . VAL B 2 331 ? 79.471  58.073  57.328 1.00 105.28 ? 331 VAL B O   1 
ATOM   2450 C CB  . VAL B 2 331 ? 78.816  56.385  60.079 1.00 118.19 ? 331 VAL B CB  1 
ATOM   2451 C CG1 . VAL B 2 331 ? 78.108  57.716  60.173 1.00 119.43 ? 331 VAL B CG1 1 
ATOM   2452 C CG2 . VAL B 2 331 ? 77.904  55.295  60.552 1.00 125.43 ? 331 VAL B CG2 1 
ATOM   2453 N N   . GLY B 2 332 ? 81.319  57.449  58.405 1.00 130.81 ? 332 GLY B N   1 
ATOM   2454 C CA  . GLY B 2 332 ? 82.114  58.506  57.809 1.00 166.97 ? 332 GLY B CA  1 
ATOM   2455 C C   . GLY B 2 332 ? 82.042  58.474  56.288 1.00 127.90 ? 332 GLY B C   1 
ATOM   2456 O O   . GLY B 2 332 ? 81.754  59.498  55.675 1.00 148.65 ? 332 GLY B O   1 
ATOM   2457 N N   . LEU B 2 333 ? 82.303  57.310  55.673 1.00 132.41 ? 333 LEU B N   1 
ATOM   2458 C CA  . LEU B 2 333 ? 82.247  57.185  54.228 1.00 143.52 ? 333 LEU B CA  1 
ATOM   2459 C C   . LEU B 2 333 ? 80.859  57.520  53.707 1.00 132.58 ? 333 LEU B C   1 
ATOM   2460 O O   . LEU B 2 333 ? 80.800  58.155  52.651 1.00 150.50 ? 333 LEU B O   1 
ATOM   2461 C CB  . LEU B 2 333 ? 82.683  55.785  53.798 1.00 141.98 ? 333 LEU B CB  1 
ATOM   2462 C CG  . LEU B 2 333 ? 84.161  55.464  53.945 1.00 167.31 ? 333 LEU B CG  1 
ATOM   2463 C CD1 . LEU B 2 333 ? 84.402  54.041  53.480 1.00 242.28 ? 333 LEU B CD1 1 
ATOM   2464 C CD2 . LEU B 2 333 ? 85.024  56.428  53.151 1.00 231.54 ? 333 LEU B CD2 1 
ATOM   2465 N N   . SER B 2 334 ? 79.767  57.129  54.389 1.00 111.80 ? 334 SER B N   1 
ATOM   2466 C CA  . SER B 2 334 ? 78.430  57.506  53.934 1.00 133.24 ? 334 SER B CA  1 
ATOM   2467 C C   . SER B 2 334 ? 78.255  59.031  53.858 1.00 146.93 ? 334 SER B C   1 
ATOM   2468 O O   . SER B 2 334 ? 77.640  59.534  52.916 1.00 173.46 ? 334 SER B O   1 
ATOM   2469 C CB  . SER B 2 334 ? 77.343  56.904  54.747 1.00 127.65 ? 334 SER B CB  1 
ATOM   2470 O OG  . SER B 2 334 ? 77.107  57.626  55.920 1.00 120.22 ? 334 SER B OG  1 
ATOM   2471 N N   . CYS B 2 335 ? 78.802  59.776  54.823 1.00 132.50 ? 335 CYS B N   1 
ATOM   2472 C CA  . CYS B 2 335 ? 78.717  61.235  54.847 1.00 109.66 ? 335 CYS B CA  1 
ATOM   2473 C C   . CYS B 2 335 ? 79.663  61.866  53.826 1.00 120.13 ? 335 CYS B C   1 
ATOM   2474 O O   . CYS B 2 335 ? 79.334  62.869  53.216 1.00 185.36 ? 335 CYS B O   1 
ATOM   2475 C CB  . CYS B 2 335 ? 79.043  61.740  56.232 1.00 131.12 ? 335 CYS B CB  1 
ATOM   2476 S SG  . CYS B 2 335 ? 77.997  60.980  57.487 1.00 174.77 ? 335 CYS B SG  1 
ATOM   2477 N N   . PHE B 2 336 ? 80.837  61.282  53.588 1.00 120.28 ? 336 PHE B N   1 
ATOM   2478 C CA  . PHE B 2 336 ? 81.707  61.702  52.502 1.00 110.02 ? 336 PHE B CA  1 
ATOM   2479 C C   . PHE B 2 336 ? 81.001  61.506  51.157 1.00 150.51 ? 336 PHE B C   1 
ATOM   2480 O O   . PHE B 2 336 ? 81.115  62.330  50.268 1.00 163.71 ? 336 PHE B O   1 
ATOM   2481 C CB  . PHE B 2 336 ? 82.971  60.866  52.580 1.00 160.26 ? 336 PHE B CB  1 
ATOM   2482 C CG  . PHE B 2 336 ? 84.146  61.353  51.785 1.00 172.80 ? 336 PHE B CG  1 
ATOM   2483 C CD1 . PHE B 2 336 ? 84.956  62.363  52.271 1.00 147.00 ? 336 PHE B CD1 1 
ATOM   2484 C CD2 . PHE B 2 336 ? 84.445  60.775  50.565 1.00 177.69 ? 336 PHE B CD2 1 
ATOM   2485 C CE1 . PHE B 2 336 ? 86.047  62.795  51.539 1.00 202.30 ? 336 PHE B CE1 1 
ATOM   2486 C CE2 . PHE B 2 336 ? 85.542  61.209  49.830 1.00 223.40 ? 336 PHE B CE2 1 
ATOM   2487 C CZ  . PHE B 2 336 ? 86.334  62.218  50.320 1.00 242.55 ? 336 PHE B CZ  1 
ATOM   2488 N N   . GLY B 2 337 ? 80.228  60.425  50.997 1.00 142.80 ? 337 GLY B N   1 
ATOM   2489 C CA  . GLY B 2 337 ? 79.348  60.238  49.856 1.00 144.04 ? 337 GLY B CA  1 
ATOM   2490 C C   . GLY B 2 337 ? 78.227  61.260  49.770 1.00 131.10 ? 337 GLY B C   1 
ATOM   2491 O O   . GLY B 2 337 ? 77.931  61.707  48.667 1.00 225.13 ? 337 GLY B O   1 
ATOM   2492 N N   . SER B 2 338 ? 77.598  61.640  50.888 1.00 78.14  ? 338 SER B N   1 
ATOM   2493 C CA  . SER B 2 338 ? 76.477  62.577  50.877 1.00 111.16 ? 338 SER B CA  1 
ATOM   2494 C C   . SER B 2 338 ? 76.915  64.025  50.630 1.00 95.23  ? 338 SER B C   1 
ATOM   2495 O O   . SER B 2 338 ? 76.166  64.794  50.052 1.00 168.22 ? 338 SER B O   1 
ATOM   2496 C CB  . SER B 2 338 ? 75.664  62.457  52.142 1.00 165.33 ? 338 SER B CB  1 
ATOM   2497 O OG  . SER B 2 338 ? 75.003  61.202  52.204 1.00 216.22 ? 338 SER B OG  1 
ATOM   2498 N N   . VAL B 2 339 ? 78.100  64.441  51.077 1.00 118.11 ? 339 VAL B N   1 
ATOM   2499 C CA  . VAL B 2 339 ? 78.639  65.756  50.757 1.00 134.15 ? 339 VAL B CA  1 
ATOM   2500 C C   . VAL B 2 339 ? 78.976  65.778  49.273 1.00 157.29 ? 339 VAL B C   1 
ATOM   2501 O O   . VAL B 2 339 ? 78.614  66.733  48.595 1.00 190.29 ? 339 VAL B O   1 
ATOM   2502 C CB  . VAL B 2 339 ? 79.865  66.136  51.610 1.00 133.46 ? 339 VAL B CB  1 
ATOM   2503 C CG1 . VAL B 2 339 ? 80.615  67.368  51.131 1.00 174.18 ? 339 VAL B CG1 1 
ATOM   2504 C CG2 . VAL B 2 339 ? 79.429  66.381  53.024 1.00 168.61 ? 339 VAL B CG2 1 
ATOM   2505 N N   . ASN B 2 340 ? 79.642  64.736  48.779 1.00 102.49 ? 340 ASN B N   1 
ATOM   2506 C CA  . ASN B 2 340 ? 79.960  64.619  47.363 1.00 135.19 ? 340 ASN B CA  1 
ATOM   2507 C C   . ASN B 2 340 ? 78.710  64.734  46.477 1.00 117.21 ? 340 ASN B C   1 
ATOM   2508 O O   . ASN B 2 340 ? 78.700  65.493  45.496 1.00 107.60 ? 340 ASN B O   1 
ATOM   2509 C CB  . ASN B 2 340 ? 80.740  63.322  47.133 1.00 128.52 ? 340 ASN B CB  1 
ATOM   2510 C CG  . ASN B 2 340 ? 81.086  63.135  45.680 1.00 128.02 ? 340 ASN B CG  1 
ATOM   2511 O OD1 . ASN B 2 340 ? 81.604  64.063  45.054 1.00 136.12 ? 340 ASN B OD1 1 
ATOM   2512 N ND2 . ASN B 2 340 ? 80.786  61.967  45.128 1.00 126.33 ? 340 ASN B ND2 1 
ATOM   2513 N N   . GLY B 2 341 ? 77.649  63.991  46.816 1.00 113.52 ? 341 GLY B N   1 
ATOM   2514 C CA  . GLY B 2 341 ? 76.388  64.002  46.078 1.00 144.63 ? 341 GLY B CA  1 
ATOM   2515 C C   . GLY B 2 341 ? 75.723  65.379  45.994 1.00 118.09 ? 341 GLY B C   1 
ATOM   2516 O O   . GLY B 2 341 ? 75.197  65.751  44.955 1.00 165.56 ? 341 GLY B O   1 
ATOM   2517 N N   . SER B 2 342 ? 75.760  66.140  47.083 1.00 100.74 ? 342 SER B N   1 
ATOM   2518 C CA  . SER B 2 342 ? 75.171  67.465  47.134 1.00 175.76 ? 342 SER B CA  1 
ATOM   2519 C C   . SER B 2 342 ? 75.960  68.471  46.299 1.00 120.58 ? 342 SER B C   1 
ATOM   2520 O O   . SER B 2 342 ? 75.360  69.457  45.865 1.00 110.10 ? 342 SER B O   1 
ATOM   2521 C CB  . SER B 2 342 ? 75.010  67.958  48.548 1.00 257.67 ? 342 SER B CB  1 
ATOM   2522 O OG  . SER B 2 342 ? 74.219  69.132  48.545 1.00 295.62 ? 342 SER B OG  1 
ATOM   2523 N N   . LEU B 2 343 ? 77.269  68.257  46.108 1.00 109.46 ? 343 LEU B N   1 
ATOM   2524 C CA  . LEU B 2 343 ? 78.073  69.108  45.224 1.00 139.32 ? 343 LEU B CA  1 
ATOM   2525 C C   . LEU B 2 343 ? 77.796  68.740  43.774 1.00 146.54 ? 343 LEU B C   1 
ATOM   2526 O O   . LEU B 2 343 ? 77.455  69.624  42.984 1.00 144.82 ? 343 LEU B O   1 
ATOM   2527 C CB  . LEU B 2 343 ? 79.567  69.012  45.576 1.00 117.07 ? 343 LEU B CB  1 
ATOM   2528 C CG  . LEU B 2 343 ? 79.925  69.683  46.911 1.00 150.49 ? 343 LEU B CG  1 
ATOM   2529 C CD1 . LEU B 2 343 ? 81.249  69.168  47.413 1.00 159.88 ? 343 LEU B CD1 1 
ATOM   2530 C CD2 . LEU B 2 343 ? 79.937  71.231  46.856 1.00 110.27 ? 343 LEU B CD2 1 
ATOM   2531 N N   . PHE B 2 344 ? 77.925  67.451  43.440 1.00 156.92 ? 344 PHE B N   1 
ATOM   2532 C CA  . PHE B 2 344 ? 77.771  66.920  42.085 1.00 166.28 ? 344 PHE B CA  1 
ATOM   2533 C C   . PHE B 2 344 ? 76.430  67.291  41.445 1.00 128.57 ? 344 PHE B C   1 
ATOM   2534 O O   . PHE B 2 344 ? 76.384  67.691  40.273 1.00 117.63 ? 344 PHE B O   1 
ATOM   2535 C CB  . PHE B 2 344 ? 77.968  65.408  42.150 1.00 177.52 ? 344 PHE B CB  1 
ATOM   2536 C CG  . PHE B 2 344 ? 77.688  64.626  40.891 1.00 164.94 ? 344 PHE B CG  1 
ATOM   2537 C CD1 . PHE B 2 344 ? 78.189  65.039  39.665 1.00 221.91 ? 344 PHE B CD1 1 
ATOM   2538 C CD2 . PHE B 2 344 ? 76.927  63.464  40.941 1.00 206.41 ? 344 PHE B CD2 1 
ATOM   2539 C CE1 . PHE B 2 344 ? 77.940  64.311  38.510 1.00 289.47 ? 344 PHE B CE1 1 
ATOM   2540 C CE2 . PHE B 2 344 ? 76.670  62.738  39.790 1.00 280.02 ? 344 PHE B CE2 1 
ATOM   2541 C CZ  . PHE B 2 344 ? 77.174  63.165  38.578 1.00 326.17 ? 344 PHE B CZ  1 
ATOM   2542 N N   . THR B 2 345 ? 75.345  67.181  42.224 1.00 118.83 ? 345 THR B N   1 
ATOM   2543 C CA  . THR B 2 345 ? 74.000  67.469  41.726 1.00 174.91 ? 345 THR B CA  1 
ATOM   2544 C C   . THR B 2 345 ? 73.592  68.952  41.813 1.00 137.35 ? 345 THR B C   1 
ATOM   2545 O O   . THR B 2 345 ? 72.447  69.270  41.465 1.00 275.05 ? 345 THR B O   1 
ATOM   2546 C CB  . THR B 2 345 ? 72.959  66.556  42.404 1.00 237.20 ? 345 THR B CB  1 
ATOM   2547 O OG1 . THR B 2 345 ? 72.871  66.839  43.799 1.00 259.60 ? 345 THR B OG1 1 
ATOM   2548 C CG2 . THR B 2 345 ? 73.263  65.081  42.194 1.00 272.81 ? 345 THR B CG2 1 
ATOM   2549 N N   . SER B 2 346 ? 74.480  69.867  42.235 1.00 105.86 ? 346 SER B N   1 
ATOM   2550 C CA  . SER B 2 346 ? 74.151  71.290  42.433 1.00 173.26 ? 346 SER B CA  1 
ATOM   2551 C C   . SER B 2 346 ? 74.027  72.095  41.135 1.00 178.36 ? 346 SER B C   1 
ATOM   2552 O O   . SER B 2 346 ? 73.163  72.974  41.042 1.00 196.45 ? 346 SER B O   1 
ATOM   2553 C CB  . SER B 2 346 ? 75.145  71.983  43.325 1.00 194.92 ? 346 SER B CB  1 
ATOM   2554 O OG  . SER B 2 346 ? 76.421  72.080  42.702 1.00 141.18 ? 346 SER B OG  1 
ATOM   2555 N N   . SER B 2 347 ? 74.863  71.779  40.133 1.00 187.15 ? 347 SER B N   1 
ATOM   2556 C CA  . SER B 2 347 ? 75.046  72.546  38.900 1.00 158.34 ? 347 SER B CA  1 
ATOM   2557 C C   . SER B 2 347 ? 73.721  72.814  38.182 1.00 167.76 ? 347 SER B C   1 
ATOM   2558 O O   . SER B 2 347 ? 73.544  73.868  37.568 1.00 125.45 ? 347 SER B O   1 
ATOM   2559 C CB  . SER B 2 347 ? 75.959  71.780  37.972 1.00 178.86 ? 347 SER B CB  1 
ATOM   2560 O OG  . SER B 2 347 ? 76.959  71.053  38.674 1.00 208.01 ? 347 SER B OG  1 
ATOM   2561 N N   . ARG B 2 348 ? 72.803  71.827  38.235 1.00 164.70 ? 348 ARG B N   1 
ATOM   2562 C CA  . ARG B 2 348 ? 71.507  71.848  37.583 1.00 153.99 ? 348 ARG B CA  1 
ATOM   2563 C C   . ARG B 2 348 ? 70.771  73.155  37.894 1.00 132.98 ? 348 ARG B C   1 
ATOM   2564 O O   . ARG B 2 348 ? 70.173  73.741  36.989 1.00 170.09 ? 348 ARG B O   1 
ATOM   2565 C CB  . ARG B 2 348 ? 70.657  70.651  38.029 1.00 210.11 ? 348 ARG B CB  1 
ATOM   2566 C CG  . ARG B 2 348 ? 71.262  69.264  37.814 1.00 233.22 ? 348 ARG B CG  1 
ATOM   2567 C CD  . ARG B 2 348 ? 70.391  68.153  38.392 1.00 314.23 ? 348 ARG B CD  1 
ATOM   2568 N NE  . ARG B 2 348 ? 70.156  68.284  39.833 1.00 346.97 ? 348 ARG B NE  1 
ATOM   2569 C CZ  . ARG B 2 348 ? 69.021  67.996  40.481 1.00 322.28 ? 348 ARG B CZ  1 
ATOM   2570 N NH1 . ARG B 2 348 ? 68.896  68.300  41.762 1.00 310.96 ? 348 ARG B NH1 1 
ATOM   2571 N NH2 . ARG B 2 348 ? 67.990  67.405  39.884 1.00 314.59 ? 348 ARG B NH2 1 
ATOM   2572 N N   . LEU B 2 349 ? 70.795  73.601  39.161 1.00 118.85 ? 349 LEU B N   1 
ATOM   2573 C CA  . LEU B 2 349 ? 70.076  74.796  39.595 1.00 138.84 ? 349 LEU B CA  1 
ATOM   2574 C C   . LEU B 2 349 ? 70.710  76.078  39.061 1.00 92.51  ? 349 LEU B C   1 
ATOM   2575 O O   . LEU B 2 349 ? 70.031  77.016  38.688 1.00 133.99 ? 349 LEU B O   1 
ATOM   2576 C CB  . LEU B 2 349 ? 70.015  74.840  41.121 1.00 150.26 ? 349 LEU B CB  1 
ATOM   2577 C CG  . LEU B 2 349 ? 69.228  76.008  41.737 1.00 113.61 ? 349 LEU B CG  1 
ATOM   2578 C CD1 . LEU B 2 349 ? 67.779  76.057  41.262 1.00 169.32 ? 349 LEU B CD1 1 
ATOM   2579 C CD2 . LEU B 2 349 ? 69.192  75.784  43.243 1.00 235.49 ? 349 LEU B CD2 1 
ATOM   2580 N N   . PHE B 2 350 ? 72.023  76.131  38.972 1.00 125.24 ? 350 PHE B N   1 
ATOM   2581 C CA  . PHE B 2 350 ? 72.708  77.283  38.402 1.00 147.82 ? 350 PHE B CA  1 
ATOM   2582 C C   . PHE B 2 350 ? 72.464  77.393  36.896 1.00 172.38 ? 350 PHE B C   1 
ATOM   2583 O O   . PHE B 2 350 ? 72.182  78.476  36.394 1.00 168.79 ? 350 PHE B O   1 
ATOM   2584 C CB  . PHE B 2 350 ? 74.212  77.181  38.695 1.00 167.58 ? 350 PHE B CB  1 
ATOM   2585 C CG  . PHE B 2 350 ? 74.536  77.257  40.162 1.00 151.72 ? 350 PHE B CG  1 
ATOM   2586 C CD1 . PHE B 2 350 ? 74.711  78.485  40.775 1.00 130.10 ? 350 PHE B CD1 1 
ATOM   2587 C CD2 . PHE B 2 350 ? 74.636  76.105  40.929 1.00 170.27 ? 350 PHE B CD2 1 
ATOM   2588 C CE1 . PHE B 2 350 ? 74.989  78.555  42.121 1.00 143.49 ? 350 PHE B CE1 1 
ATOM   2589 C CE2 . PHE B 2 350 ? 74.918  76.173  42.281 1.00 267.09 ? 350 PHE B CE2 1 
ATOM   2590 C CZ  . PHE B 2 350 ? 75.098  77.395  42.871 1.00 285.34 ? 350 PHE B CZ  1 
ATOM   2591 N N   . PHE B 2 351 ? 72.583  76.285  36.149 1.00 162.81 ? 351 PHE B N   1 
ATOM   2592 C CA  . PHE B 2 351 ? 72.316  76.290  34.719 1.00 153.31 ? 351 PHE B CA  1 
ATOM   2593 C C   . PHE B 2 351 ? 70.896  76.797  34.469 1.00 163.47 ? 351 PHE B C   1 
ATOM   2594 O O   . PHE B 2 351 ? 70.732  77.759  33.710 1.00 133.82 ? 351 PHE B O   1 
ATOM   2595 C CB  . PHE B 2 351 ? 72.506  74.894  34.107 1.00 177.34 ? 351 PHE B CB  1 
ATOM   2596 C CG  . PHE B 2 351 ? 73.906  74.325  34.050 1.00 188.68 ? 351 PHE B CG  1 
ATOM   2597 C CD1 . PHE B 2 351 ? 75.020  75.044  34.464 1.00 122.34 ? 351 PHE B CD1 1 
ATOM   2598 C CD2 . PHE B 2 351 ? 74.106  73.027  33.566 1.00 246.65 ? 351 PHE B CD2 1 
ATOM   2599 C CE1 . PHE B 2 351 ? 76.299  74.482  34.408 1.00 186.89 ? 351 PHE B CE1 1 
ATOM   2600 C CE2 . PHE B 2 351 ? 75.379  72.466  33.512 1.00 212.83 ? 351 PHE B CE2 1 
ATOM   2601 C CZ  . PHE B 2 351 ? 76.473  73.196  33.940 1.00 219.24 ? 351 PHE B CZ  1 
ATOM   2602 N N   . VAL B 2 352 ? 69.886  76.172  35.103 1.00 168.82 ? 352 VAL B N   1 
ATOM   2603 C CA  . VAL B 2 352 ? 68.489  76.564  34.951 1.00 160.48 ? 352 VAL B CA  1 
ATOM   2604 C C   . VAL B 2 352 ? 68.269  78.021  35.376 1.00 122.29 ? 352 VAL B C   1 
ATOM   2605 O O   . VAL B 2 352 ? 67.683  78.793  34.615 1.00 192.90 ? 352 VAL B O   1 
ATOM   2606 C CB  . VAL B 2 352 ? 67.566  75.553  35.654 1.00 186.00 ? 352 VAL B CB  1 
ATOM   2607 C CG1 . VAL B 2 352 ? 66.133  76.024  35.803 1.00 194.35 ? 352 VAL B CG1 1 
ATOM   2608 C CG2 . VAL B 2 352 ? 67.578  74.226  34.883 1.00 237.71 ? 352 VAL B CG2 1 
ATOM   2609 N N   . GLY B 2 353 ? 68.749  78.428  36.545 1.00 157.62 ? 353 GLY B N   1 
ATOM   2610 C CA  . GLY B 2 353 ? 68.553  79.782  37.053 1.00 174.63 ? 353 GLY B CA  1 
ATOM   2611 C C   . GLY B 2 353 ? 69.190  80.882  36.212 1.00 139.78 ? 353 GLY B C   1 
ATOM   2612 O O   . GLY B 2 353 ? 68.694  81.993  36.212 1.00 137.05 ? 353 GLY B O   1 
ATOM   2613 N N   . SER B 2 354 ? 70.273  80.585  35.489 1.00 164.50 ? 354 SER B N   1 
ATOM   2614 C CA  . SER B 2 354 ? 70.901  81.532  34.569 1.00 203.21 ? 354 SER B CA  1 
ATOM   2615 C C   . SER B 2 354 ? 70.269  81.471  33.169 1.00 233.21 ? 354 SER B C   1 
ATOM   2616 O O   . SER B 2 354 ? 70.126  82.505  32.518 1.00 192.80 ? 354 SER B O   1 
ATOM   2617 C CB  . SER B 2 354 ? 72.411  81.341  34.553 1.00 167.05 ? 354 SER B CB  1 
ATOM   2618 O OG  . SER B 2 354 ? 72.733  80.005  34.213 1.00 212.71 ? 354 SER B OG  1 
ATOM   2619 N N   . ARG B 2 355 ? 69.872  80.279  32.695 1.00 223.75 ? 355 ARG B N   1 
ATOM   2620 C CA  . ARG B 2 355 ? 69.139  80.121  31.441 1.00 201.26 ? 355 ARG B CA  1 
ATOM   2621 C C   . ARG B 2 355 ? 67.823  80.907  31.467 1.00 191.63 ? 355 ARG B C   1 
ATOM   2622 O O   . ARG B 2 355 ? 67.505  81.589  30.488 1.00 239.15 ? 355 ARG B O   1 
ATOM   2623 C CB  . ARG B 2 355 ? 68.886  78.629  31.187 1.00 242.44 ? 355 ARG B CB  1 
ATOM   2624 C CG  . ARG B 2 355 ? 68.308  78.298  29.817 1.00 258.39 ? 355 ARG B CG  1 
ATOM   2625 C CD  . ARG B 2 355 ? 67.900  76.836  29.722 1.00 293.38 ? 355 ARG B CD  1 
ATOM   2626 N NE  . ARG B 2 355 ? 66.645  76.588  30.420 1.00 297.67 ? 355 ARG B NE  1 
ATOM   2627 C CZ  . ARG B 2 355 ? 66.093  75.398  30.665 1.00 343.75 ? 355 ARG B CZ  1 
ATOM   2628 N NH1 . ARG B 2 355 ? 64.893  75.350  31.221 1.00 344.50 ? 355 ARG B NH1 1 
ATOM   2629 N NH2 . ARG B 2 355 ? 66.718  74.271  30.361 1.00 362.83 ? 355 ARG B NH2 1 
ATOM   2630 N N   . GLU B 2 356 ? 67.061  80.811  32.575 1.00 186.47 ? 356 GLU B N   1 
ATOM   2631 C CA  . GLU B 2 356 ? 65.823  81.569  32.766 1.00 232.32 ? 356 GLU B CA  1 
ATOM   2632 C C   . GLU B 2 356 ? 66.057  83.006  33.273 1.00 212.73 ? 356 GLU B C   1 
ATOM   2633 O O   . GLU B 2 356 ? 65.089  83.714  33.582 1.00 187.89 ? 356 GLU B O   1 
ATOM   2634 C CB  . GLU B 2 356 ? 64.876  80.810  33.709 1.00 244.10 ? 356 GLU B CB  1 
ATOM   2635 C CG  . GLU B 2 356 ? 64.577  79.364  33.306 1.00 270.97 ? 356 GLU B CG  1 
ATOM   2636 C CD  . GLU B 2 356 ? 64.113  79.134  31.876 1.00 299.70 ? 356 GLU B CD  1 
ATOM   2637 O OE1 . GLU B 2 356 ? 63.418  80.015  31.328 1.00 350.54 ? 356 GLU B OE1 1 
ATOM   2638 O OE2 . GLU B 2 356 ? 64.432  78.068  31.317 1.00 217.80 ? 356 GLU B OE2 1 
ATOM   2639 N N   . GLY B 2 357 ? 67.322  83.450  33.374 1.00 177.04 ? 357 GLY B N   1 
ATOM   2640 C CA  . GLY B 2 357 ? 67.678  84.865  33.405 1.00 206.62 ? 357 GLY B CA  1 
ATOM   2641 C C   . GLY B 2 357 ? 67.674  85.516  34.789 1.00 188.55 ? 357 GLY B C   1 
ATOM   2642 O O   . GLY B 2 357 ? 67.924  86.719  34.881 1.00 151.54 ? 357 GLY B O   1 
ATOM   2643 N N   . HIS B 2 358 ? 67.412  84.749  35.861 1.00 219.50 ? 358 HIS B N   1 
ATOM   2644 C CA  . HIS B 2 358 ? 67.461  85.253  37.233 1.00 224.00 ? 358 HIS B CA  1 
ATOM   2645 C C   . HIS B 2 358 ? 68.892  85.345  37.786 1.00 181.17 ? 358 HIS B C   1 
ATOM   2646 O O   . HIS B 2 358 ? 69.149  86.177  38.644 1.00 152.94 ? 358 HIS B O   1 
ATOM   2647 C CB  . HIS B 2 358 ? 66.601  84.379  38.163 1.00 183.89 ? 358 HIS B CB  1 
ATOM   2648 C CG  . HIS B 2 358 ? 65.147  84.672  38.143 1.00 172.41 ? 358 HIS B CG  1 
ATOM   2649 N ND1 . HIS B 2 358 ? 64.157  83.846  37.664 1.00 207.56 ? 358 HIS B ND1 1 
ATOM   2650 C CD2 . HIS B 2 358 ? 64.534  85.787  38.557 1.00 261.80 ? 358 HIS B CD2 1 
ATOM   2651 C CE1 . HIS B 2 358 ? 62.983  84.455  37.794 1.00 301.94 ? 358 HIS B CE1 1 
ATOM   2652 N NE2 . HIS B 2 358 ? 63.191  85.634  38.342 1.00 306.66 ? 358 HIS B NE2 1 
ATOM   2653 N N   . LEU B 2 359 ? 69.823  84.493  37.323 1.00 127.29 ? 359 LEU B N   1 
ATOM   2654 C CA  . LEU B 2 359 ? 71.108  84.319  37.984 1.00 141.72 ? 359 LEU B CA  1 
ATOM   2655 C C   . LEU B 2 359 ? 72.281  84.762  37.090 1.00 165.99 ? 359 LEU B C   1 
ATOM   2656 O O   . LEU B 2 359 ? 72.289  84.448  35.909 1.00 150.73 ? 359 LEU B O   1 
ATOM   2657 C CB  . LEU B 2 359 ? 71.210  82.840  38.401 1.00 162.87 ? 359 LEU B CB  1 
ATOM   2658 C CG  . LEU B 2 359 ? 72.240  82.534  39.488 1.00 178.24 ? 359 LEU B CG  1 
ATOM   2659 C CD1 . LEU B 2 359 ? 71.830  83.144  40.842 1.00 184.63 ? 359 LEU B CD1 1 
ATOM   2660 C CD2 . LEU B 2 359 ? 72.458  81.035  39.590 1.00 137.19 ? 359 LEU B CD2 1 
ATOM   2661 N N   . PRO B 2 360 ? 73.314  85.486  37.628 1.00 177.24 ? 360 PRO B N   1 
ATOM   2662 C CA  . PRO B 2 360 ? 74.486  85.995  36.889 1.00 163.20 ? 360 PRO B CA  1 
ATOM   2663 C C   . PRO B 2 360 ? 75.172  85.046  35.905 1.00 173.66 ? 360 PRO B C   1 
ATOM   2664 O O   . PRO B 2 360 ? 75.371  83.857  36.183 1.00 156.91 ? 360 PRO B O   1 
ATOM   2665 C CB  . PRO B 2 360 ? 75.500  86.339  37.993 1.00 136.37 ? 360 PRO B CB  1 
ATOM   2666 C CG  . PRO B 2 360 ? 74.576  86.846  39.096 1.00 182.95 ? 360 PRO B CG  1 
ATOM   2667 C CD  . PRO B 2 360 ? 73.424  85.878  39.035 1.00 164.96 ? 360 PRO B CD  1 
ATOM   2668 N N   . SER B 2 361 ? 75.519  85.605  34.734 1.00 207.63 ? 361 SER B N   1 
ATOM   2669 C CA  . SER B 2 361 ? 75.927  84.838  33.556 1.00 230.42 ? 361 SER B CA  1 
ATOM   2670 C C   . SER B 2 361 ? 77.187  84.001  33.810 1.00 191.33 ? 361 SER B C   1 
ATOM   2671 O O   . SER B 2 361 ? 77.318  82.908  33.261 1.00 176.56 ? 361 SER B O   1 
ATOM   2672 C CB  . SER B 2 361 ? 76.114  85.750  32.364 1.00 277.16 ? 361 SER B CB  1 
ATOM   2673 O OG  . SER B 2 361 ? 77.015  86.804  32.672 1.00 329.98 ? 361 SER B OG  1 
ATOM   2674 N N   . ILE B 2 362 ? 78.114  84.496  34.644 1.00 158.13 ? 362 ILE B N   1 
ATOM   2675 C CA  . ILE B 2 362 ? 79.318  83.748  35.009 1.00 187.71 ? 362 ILE B CA  1 
ATOM   2676 C C   . ILE B 2 362 ? 78.996  82.408  35.699 1.00 179.54 ? 362 ILE B C   1 
ATOM   2677 O O   . ILE B 2 362 ? 79.716  81.429  35.501 1.00 141.29 ? 362 ILE B O   1 
ATOM   2678 C CB  . ILE B 2 362 ? 80.285  84.638  35.838 1.00 191.22 ? 362 ILE B CB  1 
ATOM   2679 C CG1 . ILE B 2 362 ? 81.556  83.902  36.310 1.00 167.31 ? 362 ILE B CG1 1 
ATOM   2680 C CG2 . ILE B 2 362 ? 79.564  85.309  37.000 1.00 186.05 ? 362 ILE B CG2 1 
ATOM   2681 C CD1 . ILE B 2 362 ? 82.413  83.321  35.192 1.00 171.19 ? 362 ILE B CD1 1 
ATOM   2682 N N   . LEU B 2 363 ? 77.938  82.318  36.513 1.00 181.69 ? 363 LEU B N   1 
ATOM   2683 C CA  . LEU B 2 363 ? 77.670  81.084  37.247 1.00 157.39 ? 363 LEU B CA  1 
ATOM   2684 C C   . LEU B 2 363 ? 77.147  79.972  36.324 1.00 156.99 ? 363 LEU B C   1 
ATOM   2685 O O   . LEU B 2 363 ? 77.031  78.841  36.781 1.00 177.25 ? 363 LEU B O   1 
ATOM   2686 C CB  . LEU B 2 363 ? 76.703  81.398  38.400 1.00 185.12 ? 363 LEU B CB  1 
ATOM   2687 C CG  . LEU B 2 363 ? 77.246  82.372  39.450 1.00 188.89 ? 363 LEU B CG  1 
ATOM   2688 C CD1 . LEU B 2 363 ? 76.218  82.702  40.532 1.00 189.71 ? 363 LEU B CD1 1 
ATOM   2689 C CD2 . LEU B 2 363 ? 78.509  81.795  40.066 1.00 181.82 ? 363 LEU B CD2 1 
ATOM   2690 N N   . SER B 2 364 ? 76.832  80.262  35.049 1.00 141.13 ? 364 SER B N   1 
ATOM   2691 C CA  . SER B 2 364 ? 76.497  79.244  34.063 1.00 187.03 ? 364 SER B CA  1 
ATOM   2692 C C   . SER B 2 364 ? 77.718  78.497  33.540 1.00 161.32 ? 364 SER B C   1 
ATOM   2693 O O   . SER B 2 364 ? 77.572  77.416  32.974 1.00 139.09 ? 364 SER B O   1 
ATOM   2694 C CB  . SER B 2 364 ? 75.768  79.872  32.886 1.00 287.06 ? 364 SER B CB  1 
ATOM   2695 O OG  . SER B 2 364 ? 76.638  80.646  32.063 1.00 284.68 ? 364 SER B OG  1 
ATOM   2696 N N   . MET B 2 365 ? 78.914  79.081  33.674 1.00 142.70 ? 365 MET B N   1 
ATOM   2697 C CA  . MET B 2 365 ? 80.017  78.731  32.790 1.00 146.31 ? 365 MET B CA  1 
ATOM   2698 C C   . MET B 2 365 ? 80.722  77.448  33.226 1.00 110.24 ? 365 MET B C   1 
ATOM   2699 O O   . MET B 2 365 ? 80.558  76.941  34.360 1.00 129.81 ? 365 MET B O   1 
ATOM   2700 C CB  . MET B 2 365 ? 80.989  79.910  32.702 1.00 135.55 ? 365 MET B CB  1 
ATOM   2701 C CG  . MET B 2 365 ? 80.299  81.106  32.056 1.00 171.52 ? 365 MET B CG  1 
ATOM   2702 S SD  . MET B 2 365 ? 81.386  82.423  31.536 1.00 234.83 ? 365 MET B SD  1 
ATOM   2703 C CE  . MET B 2 365 ? 80.176  83.634  31.008 1.00 279.72 ? 365 MET B CE  1 
ATOM   2704 N N   . ILE B 2 366 ? 81.521  76.932  32.284 1.00 83.54  ? 366 ILE B N   1 
ATOM   2705 C CA  . ILE B 2 366 ? 82.185  75.647  32.423 1.00 126.15 ? 366 ILE B CA  1 
ATOM   2706 C C   . ILE B 2 366 ? 83.658  75.791  32.024 1.00 131.48 ? 366 ILE B C   1 
ATOM   2707 O O   . ILE B 2 366 ? 83.977  76.603  31.176 1.00 168.94 ? 366 ILE B O   1 
ATOM   2708 C CB  . ILE B 2 366 ? 81.411  74.610  31.579 1.00 127.95 ? 366 ILE B CB  1 
ATOM   2709 C CG1 . ILE B 2 366 ? 79.994  74.360  32.119 1.00 124.00 ? 366 ILE B CG1 1 
ATOM   2710 C CG2 . ILE B 2 366 ? 82.186  73.302  31.440 1.00 94.85  ? 366 ILE B CG2 1 
ATOM   2711 C CD1 . ILE B 2 366 ? 79.052  73.685  31.112 1.00 222.02 ? 366 ILE B CD1 1 
ATOM   2712 N N   . HIS B 2 367 ? 84.559  75.007  32.619 1.00 152.82 ? 367 HIS B N   1 
ATOM   2713 C CA  . HIS B 2 367 ? 85.962  74.956  32.239 1.00 156.78 ? 367 HIS B CA  1 
ATOM   2714 C C   . HIS B 2 367 ? 86.147  73.988  31.068 1.00 214.93 ? 367 HIS B C   1 
ATOM   2715 O O   . HIS B 2 367 ? 86.011  72.778  31.254 1.00 149.84 ? 367 HIS B O   1 
ATOM   2716 C CB  . HIS B 2 367 ? 86.780  74.527  33.458 1.00 242.67 ? 367 HIS B CB  1 
ATOM   2717 C CG  . HIS B 2 367 ? 88.258  74.476  33.213 1.00 205.24 ? 367 HIS B CG  1 
ATOM   2718 N ND1 . HIS B 2 367 ? 89.102  75.569  33.230 1.00 205.29 ? 367 HIS B ND1 1 
ATOM   2719 C CD2 . HIS B 2 367 ? 89.016  73.404  32.957 1.00 158.92 ? 367 HIS B CD2 1 
ATOM   2720 C CE1 . HIS B 2 367 ? 90.333  75.146  32.980 1.00 278.30 ? 367 HIS B CE1 1 
ATOM   2721 N NE2 . HIS B 2 367 ? 90.306  73.835  32.809 1.00 255.15 ? 367 HIS B NE2 1 
ATOM   2722 N N   . PRO B 2 368 ? 86.420  74.480  29.830 1.00 241.70 ? 368 PRO B N   1 
ATOM   2723 C CA  . PRO B 2 368 ? 86.216  73.682  28.619 1.00 252.40 ? 368 PRO B CA  1 
ATOM   2724 C C   . PRO B 2 368 ? 87.125  72.466  28.398 1.00 248.36 ? 368 PRO B C   1 
ATOM   2725 O O   . PRO B 2 368 ? 86.745  71.581  27.640 1.00 247.99 ? 368 PRO B O   1 
ATOM   2726 C CB  . PRO B 2 368 ? 86.404  74.700  27.481 1.00 240.76 ? 368 PRO B CB  1 
ATOM   2727 C CG  . PRO B 2 368 ? 87.220  75.821  28.074 1.00 195.87 ? 368 PRO B CG  1 
ATOM   2728 C CD  . PRO B 2 368 ? 86.868  75.847  29.532 1.00 188.31 ? 368 PRO B CD  1 
ATOM   2729 N N   . GLN B 2 369 ? 88.299  72.391  29.049 1.00 190.00 ? 369 GLN B N   1 
ATOM   2730 C CA  . GLN B 2 369 ? 89.149  71.205  28.978 1.00 232.39 ? 369 GLN B CA  1 
ATOM   2731 C C   . GLN B 2 369 ? 88.619  70.034  29.829 1.00 302.13 ? 369 GLN B C   1 
ATOM   2732 O O   . GLN B 2 369 ? 88.965  68.882  29.540 1.00 292.64 ? 369 GLN B O   1 
ATOM   2733 C CB  . GLN B 2 369 ? 90.581  71.552  29.403 1.00 252.75 ? 369 GLN B CB  1 
ATOM   2734 C CG  . GLN B 2 369 ? 91.366  72.346  28.362 1.00 292.55 ? 369 GLN B CG  1 
ATOM   2735 C CD  . GLN B 2 369 ? 91.020  73.815  28.234 1.00 342.67 ? 369 GLN B CD  1 
ATOM   2736 O OE1 . GLN B 2 369 ? 90.348  74.412  29.074 1.00 321.00 ? 369 GLN B OE1 1 
ATOM   2737 N NE2 . GLN B 2 369 ? 91.493  74.433  27.161 1.00 403.00 ? 369 GLN B NE2 1 
ATOM   2738 N N   . LEU B 2 370 ? 87.807  70.306  30.876 1.00 290.89 ? 370 LEU B N   1 
ATOM   2739 C CA  . LEU B 2 370 ? 87.359  69.292  31.841 1.00 252.78 ? 370 LEU B CA  1 
ATOM   2740 C C   . LEU B 2 370 ? 85.833  69.118  31.887 1.00 243.37 ? 370 LEU B C   1 
ATOM   2741 O O   . LEU B 2 370 ? 85.367  68.113  32.440 1.00 228.15 ? 370 LEU B O   1 
ATOM   2742 C CB  . LEU B 2 370 ? 87.894  69.678  33.227 1.00 199.13 ? 370 LEU B CB  1 
ATOM   2743 C CG  . LEU B 2 370 ? 89.410  69.777  33.364 1.00 227.00 ? 370 LEU B CG  1 
ATOM   2744 C CD1 . LEU B 2 370 ? 89.777  70.334  34.723 1.00 234.47 ? 370 LEU B CD1 1 
ATOM   2745 C CD2 . LEU B 2 370 ? 90.082  68.420  33.155 1.00 319.07 ? 370 LEU B CD2 1 
ATOM   2746 N N   . LEU B 2 371 ? 85.079  70.086  31.319 1.00 185.63 ? 371 LEU B N   1 
ATOM   2747 C CA  . LEU B 2 371 ? 83.624  70.131  31.232 1.00 202.28 ? 371 LEU B CA  1 
ATOM   2748 C C   . LEU B 2 371 ? 82.968  70.170  32.632 1.00 222.30 ? 371 LEU B C   1 
ATOM   2749 O O   . LEU B 2 371 ? 81.819  69.731  32.807 1.00 278.89 ? 371 LEU B O   1 
ATOM   2750 C CB  . LEU B 2 371 ? 83.107  68.979  30.343 1.00 305.39 ? 371 LEU B CB  1 
ATOM   2751 C CG  . LEU B 2 371 ? 83.508  68.960  28.856 1.00 369.56 ? 371 LEU B CG  1 
ATOM   2752 C CD1 . LEU B 2 371 ? 83.350  70.326  28.188 1.00 377.74 ? 371 LEU B CD1 1 
ATOM   2753 C CD2 . LEU B 2 371 ? 84.924  68.418  28.648 1.00 406.32 ? 371 LEU B CD2 1 
ATOM   2754 N N   . THR B 2 372 ? 83.679  70.740  33.630 1.00 194.12 ? 372 THR B N   1 
ATOM   2755 C CA  . THR B 2 372 ? 83.203  70.877  35.009 1.00 172.72 ? 372 THR B CA  1 
ATOM   2756 C C   . THR B 2 372 ? 82.835  72.324  35.337 1.00 114.37 ? 372 THR B C   1 
ATOM   2757 O O   . THR B 2 372 ? 83.469  73.252  34.841 1.00 175.56 ? 372 THR B O   1 
ATOM   2758 C CB  . THR B 2 372 ? 84.255  70.397  36.003 1.00 226.53 ? 372 THR B CB  1 
ATOM   2759 O OG1 . THR B 2 372 ? 85.439  71.164  35.790 1.00 211.96 ? 372 THR B OG1 1 
ATOM   2760 C CG2 . THR B 2 372 ? 84.588  68.927  35.851 1.00 215.04 ? 372 THR B CG2 1 
ATOM   2761 N N   . PRO B 2 373 ? 81.731  72.578  36.077 1.00 105.52 ? 373 PRO B N   1 
ATOM   2762 C CA  . PRO B 2 373 ? 81.112  73.903  36.154 1.00 121.34 ? 373 PRO B CA  1 
ATOM   2763 C C   . PRO B 2 373 ? 81.703  74.829  37.206 1.00 113.52 ? 373 PRO B C   1 
ATOM   2764 O O   . PRO B 2 373 ? 80.964  75.385  38.008 1.00 89.34  ? 373 PRO B O   1 
ATOM   2765 C CB  . PRO B 2 373 ? 79.620  73.544  36.374 1.00 145.47 ? 373 PRO B CB  1 
ATOM   2766 C CG  . PRO B 2 373 ? 79.757  72.398  37.321 1.00 149.34 ? 373 PRO B CG  1 
ATOM   2767 C CD  . PRO B 2 373 ? 80.921  71.593  36.782 1.00 150.26 ? 373 PRO B CD  1 
ATOM   2768 N N   . VAL B 2 374 ? 83.027  75.037  37.097 1.00 81.50  ? 374 VAL B N   1 
ATOM   2769 C CA  . VAL B 2 374 ? 83.865  75.663  38.117 1.00 104.38 ? 374 VAL B CA  1 
ATOM   2770 C C   . VAL B 2 374 ? 83.286  76.851  38.915 1.00 94.29  ? 374 VAL B C   1 
ATOM   2771 O O   . VAL B 2 374 ? 83.247  76.736  40.155 1.00 176.78 ? 374 VAL B O   1 
ATOM   2772 C CB  . VAL B 2 374 ? 85.236  75.953  37.515 1.00 126.70 ? 374 VAL B CB  1 
ATOM   2773 C CG1 . VAL B 2 374 ? 86.107  76.945  38.311 1.00 127.61 ? 374 VAL B CG1 1 
ATOM   2774 C CG2 . VAL B 2 374 ? 85.930  74.577  37.336 1.00 131.96 ? 374 VAL B CG2 1 
ATOM   2775 N N   . PRO B 2 375 ? 82.791  77.949  38.357 1.00 90.53  ? 375 PRO B N   1 
ATOM   2776 C CA  . PRO B 2 375 ? 82.268  79.032  39.192 1.00 121.10 ? 375 PRO B CA  1 
ATOM   2777 C C   . PRO B 2 375 ? 81.046  78.655  40.053 1.00 147.85 ? 375 PRO B C   1 
ATOM   2778 O O   . PRO B 2 375 ? 80.874  79.250  41.121 1.00 248.21 ? 375 PRO B O   1 
ATOM   2779 C CB  . PRO B 2 375 ? 81.877  80.153  38.197 1.00 166.29 ? 375 PRO B CB  1 
ATOM   2780 C CG  . PRO B 2 375 ? 82.626  79.749  36.933 1.00 204.35 ? 375 PRO B CG  1 
ATOM   2781 C CD  . PRO B 2 375 ? 82.638  78.223  36.945 1.00 137.00 ? 375 PRO B CD  1 
ATOM   2782 N N   . SER B 2 376 ? 80.204  77.693  39.630 1.00 108.53 ? 376 SER B N   1 
ATOM   2783 C CA  . SER B 2 376 ? 79.053  77.290  40.413 1.00 124.17 ? 376 SER B CA  1 
ATOM   2784 C C   . SER B 2 376 ? 79.492  76.457  41.619 1.00 143.98 ? 376 SER B C   1 
ATOM   2785 O O   . SER B 2 376 ? 78.910  76.593  42.694 1.00 132.50 ? 376 SER B O   1 
ATOM   2786 C CB  . SER B 2 376 ? 78.053  76.499  39.561 1.00 186.06 ? 376 SER B CB  1 
ATOM   2787 O OG  . SER B 2 376 ? 78.564  75.227  39.155 1.00 129.56 ? 376 SER B OG  1 
ATOM   2788 N N   . LEU B 2 377 ? 80.496  75.570  41.455 1.00 140.63 ? 377 LEU B N   1 
ATOM   2789 C CA  . LEU B 2 377 ? 81.066  74.804  42.554 1.00 114.46 ? 377 LEU B CA  1 
ATOM   2790 C C   . LEU B 2 377 ? 81.721  75.748  43.540 1.00 81.00  ? 377 LEU B C   1 
ATOM   2791 O O   . LEU B 2 377 ? 81.427  75.678  44.722 1.00 132.77 ? 377 LEU B O   1 
ATOM   2792 C CB  . LEU B 2 377 ? 82.054  73.733  42.054 1.00 104.83 ? 377 LEU B CB  1 
ATOM   2793 C CG  . LEU B 2 377 ? 81.380  72.613  41.245 1.00 144.62 ? 377 LEU B CG  1 
ATOM   2794 C CD1 . LEU B 2 377 ? 82.385  71.625  40.727 1.00 129.16 ? 377 LEU B CD1 1 
ATOM   2795 C CD2 . LEU B 2 377 ? 80.341  71.826  42.047 1.00 193.97 ? 377 LEU B CD2 1 
ATOM   2796 N N   . VAL B 2 378 ? 82.600  76.626  43.093 1.00 79.28  ? 378 VAL B N   1 
ATOM   2797 C CA  . VAL B 2 378 ? 83.234  77.562  44.002 1.00 88.34  ? 378 VAL B CA  1 
ATOM   2798 C C   . VAL B 2 378 ? 82.229  78.432  44.759 1.00 99.18  ? 378 VAL B C   1 
ATOM   2799 O O   . VAL B 2 378 ? 82.472  78.707  45.941 1.00 220.20 ? 378 VAL B O   1 
ATOM   2800 C CB  . VAL B 2 378 ? 84.250  78.419  43.254 1.00 145.29 ? 378 VAL B CB  1 
ATOM   2801 C CG1 . VAL B 2 378 ? 84.658  79.717  43.994 1.00 129.82 ? 378 VAL B CG1 1 
ATOM   2802 C CG2 . VAL B 2 378 ? 85.431  77.517  42.878 1.00 173.14 ? 378 VAL B CG2 1 
ATOM   2803 N N   . PHE B 2 379 ? 81.110  78.864  44.187 1.00 100.45 ? 379 PHE B N   1 
ATOM   2804 C CA  . PHE B 2 379 ? 80.110  79.603  44.947 1.00 119.18 ? 379 PHE B CA  1 
ATOM   2805 C C   . PHE B 2 379 ? 79.393  78.682  45.920 1.00 79.50  ? 379 PHE B C   1 
ATOM   2806 O O   . PHE B 2 379 ? 79.204  79.075  47.075 1.00 104.52 ? 379 PHE B O   1 
ATOM   2807 C CB  . PHE B 2 379 ? 79.112  80.290  44.018 1.00 186.93 ? 379 PHE B CB  1 
ATOM   2808 C CG  . PHE B 2 379 ? 78.003  81.019  44.731 1.00 140.50 ? 379 PHE B CG  1 
ATOM   2809 C CD1 . PHE B 2 379 ? 78.170  82.308  45.233 1.00 117.92 ? 379 PHE B CD1 1 
ATOM   2810 C CD2 . PHE B 2 379 ? 76.791  80.388  44.905 1.00 99.11  ? 379 PHE B CD2 1 
ATOM   2811 C CE1 . PHE B 2 379 ? 77.112  82.936  45.872 1.00 140.11 ? 379 PHE B CE1 1 
ATOM   2812 C CE2 . PHE B 2 379 ? 75.727  81.017  45.547 1.00 137.94 ? 379 PHE B CE2 1 
ATOM   2813 C CZ  . PHE B 2 379 ? 75.889  82.288  46.027 1.00 143.09 ? 379 PHE B CZ  1 
ATOM   2814 N N   . THR B 2 380 ? 78.997  77.480  45.494 1.00 99.02  ? 380 THR B N   1 
ATOM   2815 C CA  . THR B 2 380 ? 78.365  76.499  46.387 1.00 168.89 ? 380 THR B CA  1 
ATOM   2816 C C   . THR B 2 380 ? 79.224  76.257  47.631 1.00 135.57 ? 380 THR B C   1 
ATOM   2817 O O   . THR B 2 380 ? 78.745  76.322  48.769 1.00 121.94 ? 380 THR B O   1 
ATOM   2818 C CB  . THR B 2 380 ? 78.096  75.149  45.701 1.00 145.94 ? 380 THR B CB  1 
ATOM   2819 O OG1 . THR B 2 380 ? 77.181  75.399  44.641 1.00 228.82 ? 380 THR B OG1 1 
ATOM   2820 C CG2 . THR B 2 380 ? 77.439  74.140  46.608 1.00 182.84 ? 380 THR B CG2 1 
ATOM   2821 N N   . CYS B 2 381 ? 80.489  75.983  47.370 1.00 98.46  ? 381 CYS B N   1 
ATOM   2822 C CA  . CYS B 2 381 ? 81.480  75.708  48.371 1.00 105.12 ? 381 CYS B CA  1 
ATOM   2823 C C   . CYS B 2 381 ? 81.649  76.841  49.382 1.00 59.94  ? 381 CYS B C   1 
ATOM   2824 O O   . CYS B 2 381 ? 81.572  76.655  50.583 1.00 126.87 ? 381 CYS B O   1 
ATOM   2825 C CB  . CYS B 2 381 ? 82.777  75.452  47.652 1.00 115.16 ? 381 CYS B CB  1 
ATOM   2826 S SG  . CYS B 2 381 ? 84.096  75.151  48.811 1.00 114.91 ? 381 CYS B SG  1 
ATOM   2827 N N   . VAL B 2 382 ? 81.895  78.025  48.949 1.00 79.27  ? 382 VAL B N   1 
ATOM   2828 C CA  . VAL B 2 382 ? 82.099  79.136  49.864 1.00 121.27 ? 382 VAL B CA  1 
ATOM   2829 C C   . VAL B 2 382 ? 80.825  79.440  50.637 1.00 95.48  ? 382 VAL B C   1 
ATOM   2830 O O   . VAL B 2 382 ? 80.964  79.868  51.768 1.00 123.53 ? 382 VAL B O   1 
ATOM   2831 C CB  . VAL B 2 382 ? 82.670  80.364  49.116 1.00 159.60 ? 382 VAL B CB  1 
ATOM   2832 C CG1 . VAL B 2 382 ? 82.429  81.728  49.811 1.00 108.81 ? 382 VAL B CG1 1 
ATOM   2833 C CG2 . VAL B 2 382 ? 84.151  80.028  48.824 1.00 109.85 ? 382 VAL B CG2 1 
ATOM   2834 N N   . MET B 2 383 ? 79.620  79.208  50.119 1.00 80.70  ? 383 MET B N   1 
ATOM   2835 C CA  . MET B 2 383 ? 78.452  79.368  50.975 1.00 116.78 ? 383 MET B CA  1 
ATOM   2836 C C   . MET B 2 383 ? 78.423  78.286  52.058 1.00 111.17 ? 383 MET B C   1 
ATOM   2837 O O   . MET B 2 383 ? 78.191  78.593  53.226 1.00 98.15  ? 383 MET B O   1 
ATOM   2838 C CB  . MET B 2 383 ? 77.133  79.317  50.194 1.00 159.54 ? 383 MET B CB  1 
ATOM   2839 C CG  . MET B 2 383 ? 76.872  80.531  49.332 1.00 172.36 ? 383 MET B CG  1 
ATOM   2840 S SD  . MET B 2 383 ? 77.072  82.043  50.244 1.00 180.69 ? 383 MET B SD  1 
ATOM   2841 C CE  . MET B 2 383 ? 75.985  81.806  51.642 1.00 221.04 ? 383 MET B CE  1 
ATOM   2842 N N   . THR B 2 384 ? 78.649  77.021  51.713 1.00 106.22 ? 384 THR B N   1 
ATOM   2843 C CA  . THR B 2 384 ? 78.765  75.974  52.717 1.00 107.19 ? 384 THR B CA  1 
ATOM   2844 C C   . THR B 2 384 ? 79.799  76.315  53.795 1.00 80.28  ? 384 THR B C   1 
ATOM   2845 O O   . THR B 2 384 ? 79.556  76.079  54.952 1.00 97.08  ? 384 THR B O   1 
ATOM   2846 C CB  . THR B 2 384 ? 79.094  74.621  52.045 1.00 127.90 ? 384 THR B CB  1 
ATOM   2847 O OG1 . THR B 2 384 ? 77.997  74.354  51.164 1.00 129.98 ? 384 THR B OG1 1 
ATOM   2848 C CG2 . THR B 2 384 ? 79.310  73.451  52.975 1.00 118.91 ? 384 THR B CG2 1 
ATOM   2849 N N   . LEU B 2 385 ? 80.978  76.827  53.455 1.00 84.60  ? 385 LEU B N   1 
ATOM   2850 C CA  . LEU B 2 385 ? 82.045  77.097  54.417 1.00 87.36  ? 385 LEU B CA  1 
ATOM   2851 C C   . LEU B 2 385 ? 81.739  78.250  55.341 1.00 75.24  ? 385 LEU B C   1 
ATOM   2852 O O   . LEU B 2 385 ? 82.374  78.344  56.365 1.00 81.03  ? 385 LEU B O   1 
ATOM   2853 C CB  . LEU B 2 385 ? 83.352  77.411  53.714 1.00 101.82 ? 385 LEU B CB  1 
ATOM   2854 C CG  . LEU B 2 385 ? 84.410  76.315  53.827 1.00 136.46 ? 385 LEU B CG  1 
ATOM   2855 C CD1 . LEU B 2 385 ? 83.895  74.965  53.377 1.00 124.21 ? 385 LEU B CD1 1 
ATOM   2856 C CD2 . LEU B 2 385 ? 85.646  76.752  53.061 1.00 181.82 ? 385 LEU B CD2 1 
ATOM   2857 N N   . LEU B 2 386 ? 80.783  79.118  55.042 1.00 88.09  ? 386 LEU B N   1 
ATOM   2858 C CA  . LEU B 2 386 ? 80.457  80.184  55.980 1.00 101.39 ? 386 LEU B CA  1 
ATOM   2859 C C   . LEU B 2 386 ? 79.615  79.665  57.153 1.00 97.75  ? 386 LEU B C   1 
ATOM   2860 O O   . LEU B 2 386 ? 79.561  80.309  58.200 1.00 94.82  ? 386 LEU B O   1 
ATOM   2861 C CB  . LEU B 2 386 ? 79.702  81.288  55.246 1.00 106.77 ? 386 LEU B CB  1 
ATOM   2862 C CG  . LEU B 2 386 ? 80.533  82.104  54.289 1.00 123.11 ? 386 LEU B CG  1 
ATOM   2863 C CD1 . LEU B 2 386 ? 79.591  82.971  53.445 1.00 148.11 ? 386 LEU B CD1 1 
ATOM   2864 C CD2 . LEU B 2 386 ? 81.639  82.879  55.067 1.00 144.50 ? 386 LEU B CD2 1 
ATOM   2865 N N   . TYR B 2 387 ? 78.945  78.517  57.012 1.00 88.32  ? 387 TYR B N   1 
ATOM   2866 C CA  . TYR B 2 387 ? 78.161  77.977  58.115 1.00 109.74 ? 387 TYR B CA  1 
ATOM   2867 C C   . TYR B 2 387 ? 79.052  77.465  59.253 1.00 98.22  ? 387 TYR B C   1 
ATOM   2868 O O   . TYR B 2 387 ? 78.535  77.217  60.333 1.00 88.91  ? 387 TYR B O   1 
ATOM   2869 C CB  . TYR B 2 387 ? 77.183  76.931  57.588 1.00 135.30 ? 387 TYR B CB  1 
ATOM   2870 C CG  . TYR B 2 387 ? 75.962  77.611  56.993 1.00 94.04  ? 387 TYR B CG  1 
ATOM   2871 C CD1 . TYR B 2 387 ? 76.020  78.280  55.818 1.00 100.86 ? 387 TYR B CD1 1 
ATOM   2872 C CD2 . TYR B 2 387 ? 74.760  77.575  57.625 1.00 95.52  ? 387 TYR B CD2 1 
ATOM   2873 C CE1 . TYR B 2 387 ? 74.906  78.881  55.271 1.00 125.41 ? 387 TYR B CE1 1 
ATOM   2874 C CE2 . TYR B 2 387 ? 73.645  78.164  57.101 1.00 97.23  ? 387 TYR B CE2 1 
ATOM   2875 C CZ  . TYR B 2 387 ? 73.709  78.833  55.918 1.00 126.76 ? 387 TYR B CZ  1 
ATOM   2876 O OH  . TYR B 2 387 ? 72.613  79.454  55.406 1.00 170.29 ? 387 TYR B OH  1 
ATOM   2877 N N   . ALA B 2 388 ? 80.372  77.380  59.054 1.00 72.54  ? 388 ALA B N   1 
ATOM   2878 C CA  . ALA B 2 388 ? 81.334  77.231  60.133 1.00 79.37  ? 388 ALA B CA  1 
ATOM   2879 C C   . ALA B 2 388 ? 81.247  78.332  61.187 1.00 96.04  ? 388 ALA B C   1 
ATOM   2880 O O   . ALA B 2 388 ? 81.715  78.118  62.303 1.00 161.15 ? 388 ALA B O   1 
ATOM   2881 C CB  . ALA B 2 388 ? 82.728  77.135  59.565 1.00 88.90  ? 388 ALA B CB  1 
ATOM   2882 N N   . PHE B 2 389 ? 80.643  79.484  60.890 1.00 83.82  ? 389 PHE B N   1 
ATOM   2883 C CA  . PHE B 2 389 ? 80.388  80.493  61.908 1.00 123.64 ? 389 PHE B CA  1 
ATOM   2884 C C   . PHE B 2 389 ? 79.193  80.185  62.830 1.00 113.63 ? 389 PHE B C   1 
ATOM   2885 O O   . PHE B 2 389 ? 78.982  80.901  63.816 1.00 175.17 ? 389 PHE B O   1 
ATOM   2886 C CB  . PHE B 2 389 ? 80.228  81.852  61.208 1.00 187.63 ? 389 PHE B CB  1 
ATOM   2887 C CG  . PHE B 2 389 ? 81.401  82.346  60.376 1.00 184.87 ? 389 PHE B CG  1 
ATOM   2888 C CD1 . PHE B 2 389 ? 82.702  81.883  60.559 1.00 150.02 ? 389 PHE B CD1 1 
ATOM   2889 C CD2 . PHE B 2 389 ? 81.191  83.302  59.384 1.00 222.61 ? 389 PHE B CD2 1 
ATOM   2890 C CE1 . PHE B 2 389 ? 83.738  82.357  59.770 1.00 219.04 ? 389 PHE B CE1 1 
ATOM   2891 C CE2 . PHE B 2 389 ? 82.231  83.763  58.594 1.00 223.82 ? 389 PHE B CE2 1 
ATOM   2892 C CZ  . PHE B 2 389 ? 83.504  83.288  58.801 1.00 261.77 ? 389 PHE B CZ  1 
ATOM   2893 N N   . SER B 2 390 ? 78.384  79.159  62.549 1.00 116.43 ? 390 SER B N   1 
ATOM   2894 C CA  . SER B 2 390 ? 77.246  78.791  63.391 1.00 125.12 ? 390 SER B CA  1 
ATOM   2895 C C   . SER B 2 390 ? 77.698  78.176  64.718 1.00 164.40 ? 390 SER B C   1 
ATOM   2896 O O   . SER B 2 390 ? 78.824  77.724  64.830 1.00 169.69 ? 390 SER B O   1 
ATOM   2897 C CB  . SER B 2 390 ? 76.305  77.858  62.632 1.00 123.97 ? 390 SER B CB  1 
ATOM   2898 O OG  . SER B 2 390 ? 76.945  76.633  62.333 1.00 149.25 ? 390 SER B OG  1 
ATOM   2899 N N   . LYS B 2 391 ? 76.825  78.123  65.741 1.00 207.39 ? 391 LYS B N   1 
ATOM   2900 C CA  . LYS B 2 391 ? 77.201  77.629  67.076 1.00 209.28 ? 391 LYS B CA  1 
ATOM   2901 C C   . LYS B 2 391 ? 77.161  76.093  67.189 1.00 226.07 ? 391 LYS B C   1 
ATOM   2902 O O   . LYS B 2 391 ? 78.130  75.506  67.673 1.00 220.07 ? 391 LYS B O   1 
ATOM   2903 C CB  . LYS B 2 391 ? 76.305  78.245  68.155 1.00 204.14 ? 391 LYS B CB  1 
ATOM   2904 C CG  . LYS B 2 391 ? 76.373  79.763  68.290 1.00 277.16 ? 391 LYS B CG  1 
ATOM   2905 C CD  . LYS B 2 391 ? 77.751  80.325  68.640 1.00 291.07 ? 391 LYS B CD  1 
ATOM   2906 C CE  . LYS B 2 391 ? 78.594  80.696  67.433 1.00 295.16 ? 391 LYS B CE  1 
ATOM   2907 N NZ  . LYS B 2 391 ? 79.982  81.048  67.826 1.00 286.74 ? 391 LYS B NZ  1 
ATOM   2908 N N   . ASP B 2 392 ? 76.067  75.440  66.758 1.00 222.88 ? 392 ASP B N   1 
ATOM   2909 C CA  . ASP B 2 392 ? 75.773  74.058  67.132 1.00 201.63 ? 392 ASP B CA  1 
ATOM   2910 C C   . ASP B 2 392 ? 75.014  73.338  66.019 1.00 138.08 ? 392 ASP B C   1 
ATOM   2911 O O   . ASP B 2 392 ? 74.168  73.967  65.366 1.00 148.74 ? 392 ASP B O   1 
ATOM   2912 C CB  . ASP B 2 392 ? 74.982  74.107  68.449 1.00 317.88 ? 392 ASP B CB  1 
ATOM   2913 C CG  . ASP B 2 392 ? 74.624  72.781  69.111 1.00 376.19 ? 392 ASP B CG  1 
ATOM   2914 O OD1 . ASP B 2 392 ? 75.169  71.745  68.692 1.00 349.01 ? 392 ASP B OD1 1 
ATOM   2915 O OD2 . ASP B 2 392 ? 73.788  72.799  70.038 1.00 431.20 ? 392 ASP B OD2 1 
ATOM   2916 N N   . ILE B 2 393 ? 75.281  72.029  65.810 1.00 110.15 ? 393 ILE B N   1 
ATOM   2917 C CA  . ILE B 2 393 ? 74.634  71.277  64.711 1.00 121.45 ? 393 ILE B CA  1 
ATOM   2918 C C   . ILE B 2 393 ? 73.092  71.267  64.733 1.00 106.79 ? 393 ILE B C   1 
ATOM   2919 O O   . ILE B 2 393 ? 72.460  71.477  63.694 1.00 178.01 ? 393 ILE B O   1 
ATOM   2920 C CB  . ILE B 2 393 ? 75.206  69.863  64.603 1.00 123.77 ? 393 ILE B CB  1 
ATOM   2921 C CG1 . ILE B 2 393 ? 74.918  69.207  63.267 1.00 137.34 ? 393 ILE B CG1 1 
ATOM   2922 C CG2 . ILE B 2 393 ? 74.745  68.954  65.704 1.00 202.62 ? 393 ILE B CG2 1 
ATOM   2923 C CD1 . ILE B 2 393 ? 75.812  67.938  63.055 1.00 171.24 ? 393 ILE B CD1 1 
ATOM   2924 N N   . PHE B 2 394 ? 72.466  71.132  65.893 1.00 107.71 ? 394 PHE B N   1 
ATOM   2925 C CA  . PHE B 2 394 ? 71.013  71.179  65.968 1.00 119.52 ? 394 PHE B CA  1 
ATOM   2926 C C   . PHE B 2 394 ? 70.495  72.605  65.862 1.00 105.33 ? 394 PHE B C   1 
ATOM   2927 O O   . PHE B 2 394 ? 69.278  72.745  65.670 1.00 155.48 ? 394 PHE B O   1 
ATOM   2928 C CB  . PHE B 2 394 ? 70.514  70.493  67.256 1.00 196.37 ? 394 PHE B CB  1 
ATOM   2929 C CG  . PHE B 2 394 ? 70.803  69.017  67.194 1.00 148.88 ? 394 PHE B CG  1 
ATOM   2930 C CD1 . PHE B 2 394 ? 70.055  68.223  66.347 1.00 143.84 ? 394 PHE B CD1 1 
ATOM   2931 C CD2 . PHE B 2 394 ? 71.819  68.453  67.942 1.00 167.02 ? 394 PHE B CD2 1 
ATOM   2932 C CE1 . PHE B 2 394 ? 70.310  66.874  66.256 1.00 173.67 ? 394 PHE B CE1 1 
ATOM   2933 C CE2 . PHE B 2 394 ? 72.088  67.101  67.845 1.00 207.07 ? 394 PHE B CE2 1 
ATOM   2934 C CZ  . PHE B 2 394 ? 71.341  66.329  66.999 1.00 193.00 ? 394 PHE B CZ  1 
ATOM   2935 N N   . SER B 2 395 ? 71.355  73.642  65.987 1.00 120.03 ? 395 SER B N   1 
ATOM   2936 C CA  . SER B 2 395 ? 70.939  75.006  65.682 1.00 182.72 ? 395 SER B CA  1 
ATOM   2937 C C   . SER B 2 395 ? 70.707  75.082  64.176 1.00 121.13 ? 395 SER B C   1 
ATOM   2938 O O   . SER B 2 395 ? 69.678  75.558  63.672 1.00 131.85 ? 395 SER B O   1 
ATOM   2939 C CB  . SER B 2 395 ? 71.919  76.051  66.191 1.00 211.54 ? 395 SER B CB  1 
ATOM   2940 O OG  . SER B 2 395 ? 71.219  77.212  66.649 1.00 275.59 ? 395 SER B OG  1 
ATOM   2941 N N   . VAL B 2 396 ? 71.681  74.580  63.419 1.00 112.11 ? 396 VAL B N   1 
ATOM   2942 C CA  . VAL B 2 396 ? 71.618  74.615  61.961 1.00 136.77 ? 396 VAL B CA  1 
ATOM   2943 C C   . VAL B 2 396 ? 70.514  73.688  61.441 1.00 95.31  ? 396 VAL B C   1 
ATOM   2944 O O   . VAL B 2 396 ? 69.899  74.029  60.434 1.00 118.88 ? 396 VAL B O   1 
ATOM   2945 C CB  . VAL B 2 396 ? 73.006  74.351  61.348 1.00 101.54 ? 396 VAL B CB  1 
ATOM   2946 C CG1 . VAL B 2 396 ? 73.020  74.517  59.865 1.00 116.60 ? 396 VAL B CG1 1 
ATOM   2947 C CG2 . VAL B 2 396 ? 73.980  75.366  61.918 1.00 116.88 ? 396 VAL B CG2 1 
ATOM   2948 N N   . ILE B 2 397 ? 70.228  72.550  62.068 1.00 78.62  ? 397 ILE B N   1 
ATOM   2949 C CA  . ILE B 2 397 ? 69.141  71.710  61.606 1.00 91.09  ? 397 ILE B CA  1 
ATOM   2950 C C   . ILE B 2 397 ? 67.821  72.460  61.787 1.00 90.97  ? 397 ILE B C   1 
ATOM   2951 O O   . ILE B 2 397 ? 66.937  72.322  60.949 1.00 90.39  ? 397 ILE B O   1 
ATOM   2952 C CB  . ILE B 2 397 ? 69.183  70.294  62.251 1.00 89.48  ? 397 ILE B CB  1 
ATOM   2953 C CG1 . ILE B 2 397 ? 70.305  69.460  61.635 1.00 72.50  ? 397 ILE B CG1 1 
ATOM   2954 C CG2 . ILE B 2 397 ? 67.890  69.477  62.168 1.00 82.11  ? 397 ILE B CG2 1 
ATOM   2955 C CD1 . ILE B 2 397 ? 70.652  68.210  62.371 1.00 96.54  ? 397 ILE B CD1 1 
ATOM   2956 N N   . ASN B 2 398 ? 67.634  73.200  62.874 1.00 87.70  ? 398 ASN B N   1 
ATOM   2957 C CA  . ASN B 2 398 ? 66.418  73.979  63.069 1.00 144.51 ? 398 ASN B CA  1 
ATOM   2958 C C   . ASN B 2 398 ? 66.305  75.030  61.974 1.00 142.16 ? 398 ASN B C   1 
ATOM   2959 O O   . ASN B 2 398 ? 65.229  75.215  61.379 1.00 172.11 ? 398 ASN B O   1 
ATOM   2960 C CB  . ASN B 2 398 ? 66.333  74.541  64.503 1.00 118.51 ? 398 ASN B CB  1 
ATOM   2961 C CG  . ASN B 2 398 ? 66.067  73.433  65.532 1.00 174.54 ? 398 ASN B CG  1 
ATOM   2962 O OD1 . ASN B 2 398 ? 65.663  72.292  65.244 1.00 118.81 ? 398 ASN B OD1 1 
ATOM   2963 N ND2 . ASN B 2 398 ? 66.297  73.748  66.792 1.00 240.15 ? 398 ASN B ND2 1 
ATOM   2964 N N   . PHE B 2 399 ? 67.403  75.734  61.723 1.00 115.25 ? 399 PHE B N   1 
ATOM   2965 C CA  . PHE B 2 399 ? 67.438  76.763  60.689 1.00 136.36 ? 399 PHE B CA  1 
ATOM   2966 C C   . PHE B 2 399 ? 67.115  76.225  59.296 1.00 118.61 ? 399 PHE B C   1 
ATOM   2967 O O   . PHE B 2 399 ? 66.197  76.731  58.645 1.00 135.83 ? 399 PHE B O   1 
ATOM   2968 C CB  . PHE B 2 399 ? 68.817  77.396  60.728 1.00 140.44 ? 399 PHE B CB  1 
ATOM   2969 C CG  . PHE B 2 399 ? 69.048  78.487  59.724 1.00 110.37 ? 399 PHE B CG  1 
ATOM   2970 C CD1 . PHE B 2 399 ? 68.529  79.745  59.901 1.00 119.37 ? 399 PHE B CD1 1 
ATOM   2971 C CD2 . PHE B 2 399 ? 69.797  78.234  58.601 1.00 128.86 ? 399 PHE B CD2 1 
ATOM   2972 C CE1 . PHE B 2 399 ? 68.760  80.733  58.974 1.00 121.51 ? 399 PHE B CE1 1 
ATOM   2973 C CE2 . PHE B 2 399 ? 70.022  79.224  57.670 1.00 134.25 ? 399 PHE B CE2 1 
ATOM   2974 C CZ  . PHE B 2 399 ? 69.513  80.479  57.868 1.00 154.66 ? 399 PHE B CZ  1 
ATOM   2975 N N   . PHE B 2 400 ? 67.850  75.205  58.846 1.00 91.53  ? 400 PHE B N   1 
ATOM   2976 C CA  . PHE B 2 400 ? 67.532  74.503  57.613 1.00 108.32 ? 400 PHE B CA  1 
ATOM   2977 C C   . PHE B 2 400 ? 66.037  74.105  57.561 1.00 135.09 ? 400 PHE B C   1 
ATOM   2978 O O   . PHE B 2 400 ? 65.378  74.352  56.548 1.00 108.24 ? 400 PHE B O   1 
ATOM   2979 C CB  . PHE B 2 400 ? 68.431  73.264  57.490 1.00 119.17 ? 400 PHE B CB  1 
ATOM   2980 C CG  . PHE B 2 400 ? 67.942  72.222  56.526 1.00 101.19 ? 400 PHE B CG  1 
ATOM   2981 C CD1 . PHE B 2 400 ? 68.362  72.253  55.233 1.00 105.46 ? 400 PHE B CD1 1 
ATOM   2982 C CD2 . PHE B 2 400 ? 67.044  71.231  56.920 1.00 128.11 ? 400 PHE B CD2 1 
ATOM   2983 C CE1 . PHE B 2 400 ? 67.884  71.309  54.321 1.00 228.99 ? 400 PHE B CE1 1 
ATOM   2984 C CE2 . PHE B 2 400 ? 66.573  70.281  56.028 1.00 197.66 ? 400 PHE B CE2 1 
ATOM   2985 C CZ  . PHE B 2 400 ? 66.994  70.322  54.720 1.00 244.05 ? 400 PHE B CZ  1 
ATOM   2986 N N   . SER B 2 401 ? 65.507  73.482  58.640 1.00 91.91  ? 401 SER B N   1 
ATOM   2987 C CA  . SER B 2 401 ? 64.171  72.926  58.629 1.00 114.31 ? 401 SER B CA  1 
ATOM   2988 C C   . SER B 2 401 ? 63.110  74.003  58.440 1.00 139.43 ? 401 SER B C   1 
ATOM   2989 O O   . SER B 2 401 ? 62.176  73.809  57.646 1.00 107.65 ? 401 SER B O   1 
ATOM   2990 C CB  . SER B 2 401 ? 63.891  72.130  59.847 1.00 148.00 ? 401 SER B CB  1 
ATOM   2991 O OG  . SER B 2 401 ? 64.766  71.017  59.904 1.00 141.05 ? 401 SER B OG  1 
ATOM   2992 N N   . PHE B 2 402 ? 63.254  75.132  59.135 1.00 138.77 ? 402 PHE B N   1 
ATOM   2993 C CA  . PHE B 2 402 ? 62.298  76.220  58.973 1.00 157.66 ? 402 PHE B CA  1 
ATOM   2994 C C   . PHE B 2 402 ? 62.148  76.622  57.494 1.00 104.89 ? 402 PHE B C   1 
ATOM   2995 O O   . PHE B 2 402 ? 61.048  76.578  56.932 1.00 112.25 ? 402 PHE B O   1 
ATOM   2996 C CB  . PHE B 2 402 ? 62.672  77.387  59.887 1.00 139.77 ? 402 PHE B CB  1 
ATOM   2997 C CG  . PHE B 2 402 ? 61.650  78.499  59.836 1.00 157.66 ? 402 PHE B CG  1 
ATOM   2998 C CD1 . PHE B 2 402 ? 61.768  79.514  58.892 1.00 160.72 ? 402 PHE B CD1 1 
ATOM   2999 C CD2 . PHE B 2 402 ? 60.563  78.521  60.710 1.00 194.31 ? 402 PHE B CD2 1 
ATOM   3000 C CE1 . PHE B 2 402 ? 60.847  80.542  58.830 1.00 147.62 ? 402 PHE B CE1 1 
ATOM   3001 C CE2 . PHE B 2 402 ? 59.633  79.546  60.647 1.00 212.22 ? 402 PHE B CE2 1 
ATOM   3002 C CZ  . PHE B 2 402 ? 59.775  80.549  59.705 1.00 199.34 ? 402 PHE B CZ  1 
ATOM   3003 N N   . PHE B 2 403 ? 63.246  76.982  56.855 1.00 74.67  ? 403 PHE B N   1 
ATOM   3004 C CA  . PHE B 2 403 ? 63.169  77.430  55.467 1.00 105.23 ? 403 PHE B CA  1 
ATOM   3005 C C   . PHE B 2 403 ? 62.858  76.295  54.484 1.00 100.00 ? 403 PHE B C   1 
ATOM   3006 O O   . PHE B 2 403 ? 62.189  76.574  53.489 1.00 127.33 ? 403 PHE B O   1 
ATOM   3007 C CB  . PHE B 2 403 ? 64.440  78.215  55.104 1.00 120.74 ? 403 PHE B CB  1 
ATOM   3008 C CG  . PHE B 2 403 ? 64.462  79.461  55.947 1.00 110.63 ? 403 PHE B CG  1 
ATOM   3009 C CD1 . PHE B 2 403 ? 63.605  80.494  55.629 1.00 149.68 ? 403 PHE B CD1 1 
ATOM   3010 C CD2 . PHE B 2 403 ? 65.277  79.568  57.078 1.00 105.98 ? 403 PHE B CD2 1 
ATOM   3011 C CE1 . PHE B 2 403 ? 63.579  81.626  56.416 1.00 167.88 ? 403 PHE B CE1 1 
ATOM   3012 C CE2 . PHE B 2 403 ? 65.266  80.698  57.848 1.00 106.44 ? 403 PHE B CE2 1 
ATOM   3013 C CZ  . PHE B 2 403 ? 64.397  81.706  57.511 1.00 157.95 ? 403 PHE B CZ  1 
ATOM   3014 N N   . ASN B 2 404 ? 63.320  75.057  54.712 1.00 77.16  ? 404 ASN B N   1 
ATOM   3015 C CA  . ASN B 2 404 ? 62.962  73.938  53.869 1.00 84.53  ? 404 ASN B CA  1 
ATOM   3016 C C   . ASN B 2 404 ? 61.453  73.719  53.861 1.00 96.02  ? 404 ASN B C   1 
ATOM   3017 O O   . ASN B 2 404 ? 60.852  73.648  52.763 1.00 141.74 ? 404 ASN B O   1 
ATOM   3018 C CB  . ASN B 2 404 ? 63.739  72.704  54.270 1.00 121.76 ? 404 ASN B CB  1 
ATOM   3019 C CG  . ASN B 2 404 ? 63.460  71.529  53.349 1.00 145.06 ? 404 ASN B CG  1 
ATOM   3020 O OD1 . ASN B 2 404 ? 63.766  71.605  52.156 1.00 138.39 ? 404 ASN B OD1 1 
ATOM   3021 N ND2 . ASN B 2 404 ? 62.885  70.447  53.879 1.00 141.53 ? 404 ASN B ND2 1 
ATOM   3022 N N   . TRP B 2 405 ? 60.820  73.655  55.045 1.00 118.14 ? 405 TRP B N   1 
ATOM   3023 C CA  . TRP B 2 405 ? 59.373  73.405  55.111 1.00 165.70 ? 405 TRP B CA  1 
ATOM   3024 C C   . TRP B 2 405 ? 58.562  74.631  54.675 1.00 160.29 ? 405 TRP B C   1 
ATOM   3025 O O   . TRP B 2 405 ? 57.459  74.439  54.130 1.00 104.71 ? 405 TRP B O   1 
ATOM   3026 C CB  . TRP B 2 405 ? 58.934  72.808  56.473 1.00 141.66 ? 405 TRP B CB  1 
ATOM   3027 C CG  . TRP B 2 405 ? 59.748  71.578  56.741 1.00 164.79 ? 405 TRP B CG  1 
ATOM   3028 C CD1 . TRP B 2 405 ? 60.575  71.378  57.801 1.00 242.26 ? 405 TRP B CD1 1 
ATOM   3029 C CD2 . TRP B 2 405 ? 59.887  70.397  55.906 1.00 130.02 ? 405 TRP B CD2 1 
ATOM   3030 N NE1 . TRP B 2 405 ? 61.202  70.163  57.716 1.00 262.72 ? 405 TRP B NE1 1 
ATOM   3031 C CE2 . TRP B 2 405 ? 60.804  69.536  56.554 1.00 189.39 ? 405 TRP B CE2 1 
ATOM   3032 C CE3 . TRP B 2 405 ? 59.339  69.971  54.698 1.00 124.05 ? 405 TRP B CE3 1 
ATOM   3033 C CZ2 . TRP B 2 405 ? 61.173  68.295  56.018 1.00 187.62 ? 405 TRP B CZ2 1 
ATOM   3034 C CZ3 . TRP B 2 405 ? 59.722  68.755  54.171 1.00 213.55 ? 405 TRP B CZ3 1 
ATOM   3035 C CH2 . TRP B 2 405 ? 60.619  67.919  54.828 1.00 168.14 ? 405 TRP B CH2 1 
ATOM   3036 N N   . LEU B 2 406 ? 59.090  75.853  54.882 1.00 112.16 ? 406 LEU B N   1 
ATOM   3037 C CA  . LEU B 2 406 ? 58.450  77.057  54.365 1.00 129.48 ? 406 LEU B CA  1 
ATOM   3038 C C   . LEU B 2 406 ? 58.485  77.074  52.837 1.00 120.48 ? 406 LEU B C   1 
ATOM   3039 O O   . LEU B 2 406 ? 57.504  77.489  52.230 1.00 159.97 ? 406 LEU B O   1 
ATOM   3040 C CB  . LEU B 2 406 ? 59.126  78.273  55.000 1.00 168.64 ? 406 LEU B CB  1 
ATOM   3041 C CG  . LEU B 2 406 ? 58.678  79.638  54.511 1.00 201.10 ? 406 LEU B CG  1 
ATOM   3042 C CD1 . LEU B 2 406 ? 58.573  80.613  55.680 1.00 204.05 ? 406 LEU B CD1 1 
ATOM   3043 C CD2 . LEU B 2 406 ? 59.652  80.148  53.445 1.00 211.58 ? 406 LEU B CD2 1 
ATOM   3044 N N   . CYS B 2 407 ? 59.565  76.620  52.197 1.00 107.05 ? 407 CYS B N   1 
ATOM   3045 C CA  . CYS B 2 407 ? 59.564  76.411  50.750 1.00 131.52 ? 407 CYS B CA  1 
ATOM   3046 C C   . CYS B 2 407 ? 58.576  75.346  50.268 1.00 111.53 ? 407 CYS B C   1 
ATOM   3047 O O   . CYS B 2 407 ? 57.848  75.591  49.291 1.00 167.48 ? 407 CYS B O   1 
ATOM   3048 C CB  . CYS B 2 407 ? 60.969  76.106  50.269 1.00 171.15 ? 407 CYS B CB  1 
ATOM   3049 S SG  . CYS B 2 407 ? 61.930  77.652  50.133 1.00 164.40 ? 407 CYS B SG  1 
ATOM   3050 N N   . VAL B 2 408 ? 58.502  74.208  50.952 1.00 102.24 ? 408 VAL B N   1 
ATOM   3051 C CA  . VAL B 2 408 ? 57.533  73.184  50.580 1.00 119.95 ? 408 VAL B CA  1 
ATOM   3052 C C   . VAL B 2 408 ? 56.086  73.701  50.781 1.00 135.16 ? 408 VAL B C   1 
ATOM   3053 O O   . VAL B 2 408 ? 55.187  73.362  50.003 1.00 165.27 ? 408 VAL B O   1 
ATOM   3054 C CB  . VAL B 2 408 ? 57.825  71.862  51.322 1.00 139.35 ? 408 VAL B CB  1 
ATOM   3055 C CG1 . VAL B 2 408 ? 56.741  70.812  51.142 1.00 187.77 ? 408 VAL B CG1 1 
ATOM   3056 C CG2 . VAL B 2 408 ? 59.110  71.269  50.851 1.00 158.81 ? 408 VAL B CG2 1 
ATOM   3057 N N   . ALA B 2 409 ? 55.829  74.525  51.804 1.00 106.51 ? 409 ALA B N   1 
ATOM   3058 C CA  . ALA B 2 409 ? 54.540  75.182  51.947 1.00 154.73 ? 409 ALA B CA  1 
ATOM   3059 C C   . ALA B 2 409 ? 54.170  75.999  50.696 1.00 157.57 ? 409 ALA B C   1 
ATOM   3060 O O   . ALA B 2 409 ? 53.091  75.809  50.138 1.00 140.81 ? 409 ALA B O   1 
ATOM   3061 C CB  . ALA B 2 409 ? 54.540  76.049  53.197 1.00 197.39 ? 409 ALA B CB  1 
ATOM   3062 N N   . LEU B 2 410 ? 55.053  76.905  50.245 1.00 136.77 ? 410 LEU B N   1 
ATOM   3063 C CA  . LEU B 2 410 ? 54.817  77.693  49.043 1.00 146.54 ? 410 LEU B CA  1 
ATOM   3064 C C   . LEU B 2 410 ? 54.559  76.820  47.804 1.00 129.65 ? 410 LEU B C   1 
ATOM   3065 O O   . LEU B 2 410 ? 53.766  77.206  46.942 1.00 183.45 ? 410 LEU B O   1 
ATOM   3066 C CB  . LEU B 2 410 ? 56.021  78.612  48.797 1.00 171.38 ? 410 LEU B CB  1 
ATOM   3067 C CG  . LEU B 2 410 ? 56.233  79.753  49.788 1.00 269.64 ? 410 LEU B CG  1 
ATOM   3068 C CD1 . LEU B 2 410 ? 57.559  80.445  49.499 1.00 302.36 ? 410 LEU B CD1 1 
ATOM   3069 C CD2 . LEU B 2 410 ? 55.095  80.766  49.752 1.00 347.30 ? 410 LEU B CD2 1 
ATOM   3070 N N   . ALA B 2 411 ? 55.225  75.666  47.691 1.00 129.94 ? 411 ALA B N   1 
ATOM   3071 C CA  . ALA B 2 411 ? 55.008  74.748  46.585 1.00 139.21 ? 411 ALA B CA  1 
ATOM   3072 C C   . ALA B 2 411 ? 53.617  74.098  46.639 1.00 161.34 ? 411 ALA B C   1 
ATOM   3073 O O   . ALA B 2 411 ? 52.900  74.120  45.627 1.00 244.15 ? 411 ALA B O   1 
ATOM   3074 C CB  . ALA B 2 411 ? 56.096  73.711  46.583 1.00 169.72 ? 411 ALA B CB  1 
ATOM   3075 N N   . ILE B 2 412 ? 53.203  73.531  47.786 1.00 129.25 ? 412 ILE B N   1 
ATOM   3076 C CA  . ILE B 2 412 ? 51.951  72.787  47.846 1.00 150.40 ? 412 ILE B CA  1 
ATOM   3077 C C   . ILE B 2 412 ? 50.746  73.739  47.909 1.00 186.31 ? 412 ILE B C   1 
ATOM   3078 O O   . ILE B 2 412 ? 49.714  73.416  47.317 1.00 239.47 ? 412 ILE B O   1 
ATOM   3079 C CB  . ILE B 2 412 ? 51.999  71.716  48.967 1.00 185.50 ? 412 ILE B CB  1 
ATOM   3080 C CG1 . ILE B 2 412 ? 53.146  70.730  48.730 1.00 219.61 ? 412 ILE B CG1 1 
ATOM   3081 C CG2 . ILE B 2 412 ? 50.708  70.930  49.078 1.00 205.19 ? 412 ILE B CG2 1 
ATOM   3082 C CD1 . ILE B 2 412 ? 53.187  70.192  47.283 1.00 151.94 ? 412 ILE B CD1 1 
ATOM   3083 N N   . ILE B 2 413 ? 50.844  74.900  48.576 1.00 165.01 ? 413 ILE B N   1 
ATOM   3084 C CA  . ILE B 2 413 ? 49.865  75.977  48.407 1.00 189.14 ? 413 ILE B CA  1 
ATOM   3085 C C   . ILE B 2 413 ? 49.691  76.283  46.917 1.00 152.18 ? 413 ILE B C   1 
ATOM   3086 O O   . ILE B 2 413 ? 48.566  76.329  46.408 1.00 189.23 ? 413 ILE B O   1 
ATOM   3087 C CB  . ILE B 2 413 ? 50.262  77.217  49.247 1.00 213.23 ? 413 ILE B CB  1 
ATOM   3088 C CG1 . ILE B 2 413 ? 50.038  76.920  50.736 1.00 275.87 ? 413 ILE B CG1 1 
ATOM   3089 C CG2 . ILE B 2 413 ? 49.547  78.501  48.819 1.00 259.11 ? 413 ILE B CG2 1 
ATOM   3090 C CD1 . ILE B 2 413 ? 50.673  77.927  51.679 1.00 312.98 ? 413 ILE B CD1 1 
ATOM   3091 N N   . GLY B 2 414 ? 50.820  76.481  46.235 1.00 163.36 ? 414 GLY B N   1 
ATOM   3092 C CA  . GLY B 2 414 ? 50.865  76.733  44.809 1.00 184.79 ? 414 GLY B CA  1 
ATOM   3093 C C   . GLY B 2 414 ? 50.121  75.674  43.990 1.00 151.20 ? 414 GLY B C   1 
ATOM   3094 O O   . GLY B 2 414 ? 49.393  76.031  43.071 1.00 229.33 ? 414 GLY B O   1 
ATOM   3095 N N   . MET B 2 415 ? 50.280  74.389  44.317 1.00 128.16 ? 415 MET B N   1 
ATOM   3096 C CA  . MET B 2 415 ? 49.619  73.319  43.591 1.00 177.03 ? 415 MET B CA  1 
ATOM   3097 C C   . MET B 2 415 ? 48.086  73.414  43.681 1.00 187.08 ? 415 MET B C   1 
ATOM   3098 O O   . MET B 2 415 ? 47.399  73.188  42.677 1.00 206.43 ? 415 MET B O   1 
ATOM   3099 C CB  . MET B 2 415 ? 50.084  71.957  44.113 1.00 205.79 ? 415 MET B CB  1 
ATOM   3100 C CG  . MET B 2 415 ? 49.604  70.796  43.236 1.00 206.79 ? 415 MET B CG  1 
ATOM   3101 S SD  . MET B 2 415 ? 50.053  69.190  43.876 1.00 213.10 ? 415 MET B SD  1 
ATOM   3102 C CE  . MET B 2 415 ? 48.829  69.018  45.173 1.00 230.52 ? 415 MET B CE  1 
ATOM   3103 N N   . ILE B 2 416 ? 47.542  73.747  44.858 1.00 173.89 ? 416 ILE B N   1 
ATOM   3104 C CA  . ILE B 2 416 ? 46.101  73.901  45.031 1.00 218.47 ? 416 ILE B CA  1 
ATOM   3105 C C   . ILE B 2 416 ? 45.595  75.174  44.332 1.00 220.14 ? 416 ILE B C   1 
ATOM   3106 O O   . ILE B 2 416 ? 44.568  75.132  43.639 1.00 284.17 ? 416 ILE B O   1 
ATOM   3107 C CB  . ILE B 2 416 ? 45.742  73.824  46.533 1.00 255.22 ? 416 ILE B CB  1 
ATOM   3108 C CG1 . ILE B 2 416 ? 46.125  72.456  47.121 1.00 297.33 ? 416 ILE B CG1 1 
ATOM   3109 C CG2 . ILE B 2 416 ? 44.275  74.147  46.793 1.00 315.28 ? 416 ILE B CG2 1 
ATOM   3110 C CD1 . ILE B 2 416 ? 45.641  71.245  46.335 1.00 329.73 ? 416 ILE B CD1 1 
ATOM   3111 N N   . TRP B 2 417 ? 46.304  76.296  44.496 1.00 191.61 ? 417 TRP B N   1 
ATOM   3112 C CA  . TRP B 2 417 ? 45.994  77.528  43.774 1.00 177.11 ? 417 TRP B CA  1 
ATOM   3113 C C   . TRP B 2 417 ? 46.020  77.317  42.251 1.00 146.15 ? 417 TRP B C   1 
ATOM   3114 O O   . TRP B 2 417 ? 45.151  77.845  41.555 1.00 227.60 ? 417 TRP B O   1 
ATOM   3115 C CB  . TRP B 2 417 ? 46.971  78.606  44.246 1.00 233.44 ? 417 TRP B CB  1 
ATOM   3116 C CG  . TRP B 2 417 ? 46.745  80.020  43.777 1.00 261.96 ? 417 TRP B CG  1 
ATOM   3117 C CD1 . TRP B 2 417 ? 46.205  81.016  44.536 1.00 274.66 ? 417 TRP B CD1 1 
ATOM   3118 C CD2 . TRP B 2 417 ? 47.080  80.625  42.496 1.00 266.40 ? 417 TRP B CD2 1 
ATOM   3119 N NE1 . TRP B 2 417 ? 46.162  82.186  43.823 1.00 282.04 ? 417 TRP B NE1 1 
ATOM   3120 C CE2 . TRP B 2 417 ? 46.691  81.988  42.569 1.00 294.62 ? 417 TRP B CE2 1 
ATOM   3121 C CE3 . TRP B 2 417 ? 47.659  80.160  41.300 1.00 249.54 ? 417 TRP B CE3 1 
ATOM   3122 C CZ2 . TRP B 2 417 ? 46.869  82.875  41.493 1.00 327.13 ? 417 TRP B CZ2 1 
ATOM   3123 C CZ3 . TRP B 2 417 ? 47.838  81.033  40.241 1.00 355.27 ? 417 TRP B CZ3 1 
ATOM   3124 C CH2 . TRP B 2 417 ? 47.448  82.375  40.341 1.00 374.56 ? 417 TRP B CH2 1 
ATOM   3125 N N   . LEU B 2 418 ? 46.959  76.503  41.735 1.00 160.27 ? 418 LEU B N   1 
ATOM   3126 C CA  . LEU B 2 418 ? 47.014  76.138  40.319 1.00 208.45 ? 418 LEU B CA  1 
ATOM   3127 C C   . LEU B 2 418 ? 45.861  75.201  39.905 1.00 221.40 ? 418 LEU B C   1 
ATOM   3128 O O   . LEU B 2 418 ? 45.305  75.399  38.817 1.00 282.34 ? 418 LEU B O   1 
ATOM   3129 C CB  . LEU B 2 418 ? 48.382  75.521  40.003 1.00 257.09 ? 418 LEU B CB  1 
ATOM   3130 C CG  . LEU B 2 418 ? 48.610  75.089  38.552 1.00 313.72 ? 418 LEU B CG  1 
ATOM   3131 C CD1 . LEU B 2 418 ? 48.521  76.274  37.594 1.00 352.28 ? 418 LEU B CD1 1 
ATOM   3132 C CD2 . LEU B 2 418 ? 49.948  74.379  38.405 1.00 344.27 ? 418 LEU B CD2 1 
ATOM   3133 N N   . ARG B 2 419 ? 45.480  74.207  40.729 1.00 190.97 ? 419 ARG B N   1 
ATOM   3134 C CA  . ARG B 2 419 ? 44.325  73.351  40.450 1.00 231.91 ? 419 ARG B CA  1 
ATOM   3135 C C   . ARG B 2 419 ? 43.017  74.159  40.373 1.00 237.63 ? 419 ARG B C   1 
ATOM   3136 O O   . ARG B 2 419 ? 42.138  73.824  39.571 1.00 269.30 ? 419 ARG B O   1 
ATOM   3137 C CB  . ARG B 2 419 ? 44.230  72.224  41.489 1.00 269.95 ? 419 ARG B CB  1 
ATOM   3138 C CG  . ARG B 2 419 ? 43.204  71.154  41.148 1.00 300.20 ? 419 ARG B CG  1 
ATOM   3139 C CD  . ARG B 2 419 ? 43.093  70.063  42.199 1.00 308.83 ? 419 ARG B CD  1 
ATOM   3140 N NE  . ARG B 2 419 ? 44.195  69.105  42.173 1.00 278.92 ? 419 ARG B NE  1 
ATOM   3141 C CZ  . ARG B 2 419 ? 44.181  67.897  42.736 1.00 260.45 ? 419 ARG B CZ  1 
ATOM   3142 N NH1 . ARG B 2 419 ? 45.252  67.137  42.677 1.00 257.63 ? 419 ARG B NH1 1 
ATOM   3143 N NH2 . ARG B 2 419 ? 43.115  67.431  43.362 1.00 270.38 ? 419 ARG B NH2 1 
ATOM   3144 N N   . HIS B 2 420 ? 42.892  75.216  41.191 1.00 227.09 ? 420 HIS B N   1 
ATOM   3145 C CA  . HIS B 2 420 ? 41.808  76.190  41.106 1.00 244.11 ? 420 HIS B CA  1 
ATOM   3146 C C   . HIS B 2 420 ? 41.892  77.063  39.837 1.00 205.40 ? 420 HIS B C   1 
ATOM   3147 O O   . HIS B 2 420 ? 40.915  77.168  39.099 1.00 209.10 ? 420 HIS B O   1 
ATOM   3148 C CB  . HIS B 2 420 ? 41.805  77.010  42.405 1.00 300.55 ? 420 HIS B CB  1 
ATOM   3149 C CG  . HIS B 2 420 ? 40.788  78.104  42.508 1.00 335.77 ? 420 HIS B CG  1 
ATOM   3150 N ND1 . HIS B 2 420 ? 40.840  79.305  41.829 1.00 339.73 ? 420 HIS B ND1 1 
ATOM   3151 C CD2 . HIS B 2 420 ? 39.679  78.156  43.259 1.00 333.18 ? 420 HIS B CD2 1 
ATOM   3152 C CE1 . HIS B 2 420 ? 39.789  80.042  42.158 1.00 353.59 ? 420 HIS B CE1 1 
ATOM   3153 N NE2 . HIS B 2 420 ? 39.070  79.362  43.027 1.00 340.13 ? 420 HIS B NE2 1 
ATOM   3154 N N   . ARG B 2 421 ? 43.048  77.702  39.589 1.00 219.36 ? 421 ARG B N   1 
ATOM   3155 C CA  . ARG B 2 421 ? 43.229  78.716  38.548 1.00 232.51 ? 421 ARG B CA  1 
ATOM   3156 C C   . ARG B 2 421 ? 43.237  78.143  37.120 1.00 257.10 ? 421 ARG B C   1 
ATOM   3157 O O   . ARG B 2 421 ? 42.735  78.809  36.209 1.00 321.62 ? 421 ARG B O   1 
ATOM   3158 C CB  . ARG B 2 421 ? 44.538  79.482  38.816 1.00 285.93 ? 421 ARG B CB  1 
ATOM   3159 C CG  . ARG B 2 421 ? 44.729  80.772  38.023 1.00 272.84 ? 421 ARG B CG  1 
ATOM   3160 C CD  . ARG B 2 421 ? 43.784  81.883  38.456 1.00 309.39 ? 421 ARG B CD  1 
ATOM   3161 N NE  . ARG B 2 421 ? 43.988  82.282  39.848 1.00 354.46 ? 421 ARG B NE  1 
ATOM   3162 C CZ  . ARG B 2 421 ? 43.228  83.135  40.532 1.00 400.90 ? 421 ARG B CZ  1 
ATOM   3163 N NH1 . ARG B 2 421 ? 43.511  83.398  41.796 1.00 430.94 ? 421 ARG B NH1 1 
ATOM   3164 N NH2 . ARG B 2 421 ? 42.187  83.723  39.962 1.00 384.36 ? 421 ARG B NH2 1 
ATOM   3165 N N   . LYS B 2 422 ? 43.810  76.938  36.912 1.00 246.18 ? 422 LYS B N   1 
ATOM   3166 C CA  . LYS B 2 422 ? 43.891  76.275  35.610 1.00 253.41 ? 422 LYS B CA  1 
ATOM   3167 C C   . LYS B 2 422 ? 43.413  74.827  35.738 1.00 263.66 ? 422 LYS B C   1 
ATOM   3168 O O   . LYS B 2 422 ? 44.235  73.911  35.801 1.00 282.59 ? 422 LYS B O   1 
ATOM   3169 C CB  . LYS B 2 422 ? 45.320  76.328  35.056 1.00 250.31 ? 422 LYS B CB  1 
ATOM   3170 C CG  . LYS B 2 422 ? 45.806  77.720  34.680 1.00 260.98 ? 422 LYS B CG  1 
ATOM   3171 C CD  . LYS B 2 422 ? 47.053  77.670  33.804 1.00 267.03 ? 422 LYS B CD  1 
ATOM   3172 C CE  . LYS B 2 422 ? 47.617  79.028  33.434 1.00 282.51 ? 422 LYS B CE  1 
ATOM   3173 N NZ  . LYS B 2 422 ? 48.370  79.659  34.548 1.00 288.26 ? 422 LYS B NZ  1 
ATOM   3174 N N   . PRO B 2 423 ? 42.080  74.582  35.778 1.00 304.14 ? 423 PRO B N   1 
ATOM   3175 C CA  . PRO B 2 423 ? 41.551  73.235  35.979 1.00 353.03 ? 423 PRO B CA  1 
ATOM   3176 C C   . PRO B 2 423 ? 41.816  72.325  34.774 1.00 344.71 ? 423 PRO B C   1 
ATOM   3177 O O   . PRO B 2 423 ? 41.912  72.782  33.631 1.00 238.36 ? 423 PRO B O   1 
ATOM   3178 C CB  . PRO B 2 423 ? 40.045  73.461  36.217 1.00 380.83 ? 423 PRO B CB  1 
ATOM   3179 C CG  . PRO B 2 423 ? 39.743  74.764  35.521 1.00 375.49 ? 423 PRO B CG  1 
ATOM   3180 C CD  . PRO B 2 423 ? 41.010  75.582  35.638 1.00 331.09 ? 423 PRO B CD  1 
ATOM   3181 N N   . GLU B 2 424 ? 41.953  71.024  35.078 1.00 407.10 ? 424 GLU B N   1 
ATOM   3182 C CA  . GLU B 2 424 ? 42.085  69.918  34.123 1.00 454.02 ? 424 GLU B CA  1 
ATOM   3183 C C   . GLU B 2 424 ? 43.257  70.133  33.143 1.00 418.19 ? 424 GLU B C   1 
ATOM   3184 O O   . GLU B 2 424 ? 43.158  69.844  31.941 1.00 421.60 ? 424 GLU B O   1 
ATOM   3185 C CB  . GLU B 2 424 ? 40.731  69.666  33.436 1.00 521.56 ? 424 GLU B CB  1 
ATOM   3186 C CG  . GLU B 2 424 ? 40.532  68.260  32.877 1.00 582.33 ? 424 GLU B CG  1 
ATOM   3187 C CD  . GLU B 2 424 ? 40.539  67.140  33.904 1.00 638.27 ? 424 GLU B CD  1 
ATOM   3188 O OE1 . GLU B 2 424 ? 41.637  66.745  34.337 1.00 671.02 ? 424 GLU B OE1 1 
ATOM   3189 O OE2 . GLU B 2 424 ? 39.450  66.666  34.273 1.00 667.88 ? 424 GLU B OE2 1 
ATOM   3190 N N   . LEU B 2 425 ? 44.405  70.608  33.668 1.00 381.19 ? 425 LEU B N   1 
ATOM   3191 C CA  . LEU B 2 425 ? 45.626  70.831  32.883 1.00 332.25 ? 425 LEU B CA  1 
ATOM   3192 C C   . LEU B 2 425 ? 46.394  69.512  32.636 1.00 309.66 ? 425 LEU B C   1 
ATOM   3193 O O   . LEU B 2 425 ? 47.578  69.384  32.969 1.00 229.72 ? 425 LEU B O   1 
ATOM   3194 C CB  . LEU B 2 425 ? 46.463  71.897  33.618 1.00 303.53 ? 425 LEU B CB  1 
ATOM   3195 C CG  . LEU B 2 425 ? 47.697  72.466  32.906 1.00 323.68 ? 425 LEU B CG  1 
ATOM   3196 C CD1 . LEU B 2 425 ? 47.429  72.802  31.445 1.00 302.64 ? 425 LEU B CD1 1 
ATOM   3197 C CD2 . LEU B 2 425 ? 48.191  73.707  33.636 1.00 353.87 ? 425 LEU B CD2 1 
ATOM   3198 N N   . GLU B 2 426 ? 45.698  68.525  32.027 1.00 357.98 ? 426 GLU B N   1 
ATOM   3199 C CA  . GLU B 2 426 ? 46.227  67.266  31.490 1.00 373.57 ? 426 GLU B CA  1 
ATOM   3200 C C   . GLU B 2 426 ? 47.057  66.445  32.502 1.00 324.26 ? 426 GLU B C   1 
ATOM   3201 O O   . GLU B 2 426 ? 48.023  65.782  32.116 1.00 356.94 ? 426 GLU B O   1 
ATOM   3202 C CB  . GLU B 2 426 ? 47.009  67.549  30.195 1.00 443.41 ? 426 GLU B CB  1 
ATOM   3203 C CG  . GLU B 2 426 ? 46.173  68.216  29.102 1.00 538.97 ? 426 GLU B CG  1 
ATOM   3204 C CD  . GLU B 2 426 ? 46.850  68.357  27.747 1.00 614.36 ? 426 GLU B CD  1 
ATOM   3205 O OE1 . GLU B 2 426 ? 47.409  67.353  27.260 1.00 652.32 ? 426 GLU B OE1 1 
ATOM   3206 O OE2 . GLU B 2 426 ? 46.813  69.472  27.172 1.00 662.48 ? 426 GLU B OE2 1 
ATOM   3207 N N   . ARG B 2 427 ? 46.664  66.441  33.789 1.00 281.06 ? 427 ARG B N   1 
ATOM   3208 C CA  . ARG B 2 427 ? 47.464  65.894  34.892 1.00 211.30 ? 427 ARG B CA  1 
ATOM   3209 C C   . ARG B 2 427 ? 47.593  64.364  34.818 1.00 206.51 ? 427 ARG B C   1 
ATOM   3210 O O   . ARG B 2 427 ? 46.584  63.670  34.930 1.00 252.84 ? 427 ARG B O   1 
ATOM   3211 C CB  . ARG B 2 427 ? 46.813  66.249  36.227 1.00 194.42 ? 427 ARG B CB  1 
ATOM   3212 C CG  . ARG B 2 427 ? 46.634  67.742  36.455 1.00 220.05 ? 427 ARG B CG  1 
ATOM   3213 C CD  . ARG B 2 427 ? 46.069  68.061  37.830 1.00 254.00 ? 427 ARG B CD  1 
ATOM   3214 N NE  . ARG B 2 427 ? 45.886  69.505  37.955 1.00 247.42 ? 427 ARG B NE  1 
ATOM   3215 C CZ  . ARG B 2 427 ? 46.643  70.342  38.664 1.00 280.00 ? 427 ARG B CZ  1 
ATOM   3216 N NH1 . ARG B 2 427 ? 46.598  71.631  38.394 1.00 213.24 ? 427 ARG B NH1 1 
ATOM   3217 N NH2 . ARG B 2 427 ? 47.459  69.920  39.616 1.00 351.68 ? 427 ARG B NH2 1 
ATOM   3218 N N   . PRO B 2 428 ? 48.801  63.765  34.627 1.00 211.74 ? 428 PRO B N   1 
ATOM   3219 C CA  . PRO B 2 428 ? 48.967  62.305  34.649 1.00 235.46 ? 428 PRO B CA  1 
ATOM   3220 C C   . PRO B 2 428 ? 48.688  61.674  36.018 1.00 275.01 ? 428 PRO B C   1 
ATOM   3221 O O   . PRO B 2 428 ? 48.301  60.505  36.068 1.00 325.50 ? 428 PRO B O   1 
ATOM   3222 C CB  . PRO B 2 428 ? 50.433  62.067  34.228 1.00 207.50 ? 428 PRO B CB  1 
ATOM   3223 C CG  . PRO B 2 428 ? 50.889  63.379  33.618 1.00 244.29 ? 428 PRO B CG  1 
ATOM   3224 C CD  . PRO B 2 428 ? 50.075  64.437  34.343 1.00 259.49 ? 428 PRO B CD  1 
ATOM   3225 N N   . ILE B 2 429 ? 48.896  62.453  37.102 1.00 220.94 ? 429 ILE B N   1 
ATOM   3226 C CA  . ILE B 2 429 ? 48.556  62.082  38.469 1.00 222.07 ? 429 ILE B CA  1 
ATOM   3227 C C   . ILE B 2 429 ? 47.699  63.198  39.073 1.00 232.31 ? 429 ILE B C   1 
ATOM   3228 O O   . ILE B 2 429 ? 48.020  64.358  38.900 1.00 202.99 ? 429 ILE B O   1 
ATOM   3229 C CB  . ILE B 2 429 ? 49.843  61.829  39.284 1.00 192.87 ? 429 ILE B CB  1 
ATOM   3230 C CG1 . ILE B 2 429 ? 50.669  60.693  38.677 1.00 181.94 ? 429 ILE B CG1 1 
ATOM   3231 C CG2 . ILE B 2 429 ? 49.541  61.577  40.767 1.00 249.64 ? 429 ILE B CG2 1 
ATOM   3232 C CD1 . ILE B 2 429 ? 52.031  60.516  39.305 1.00 213.72 ? 429 ILE B CD1 1 
ATOM   3233 N N   . LYS B 2 430 ? 46.622  62.836  39.792 1.00 260.02 ? 430 LYS B N   1 
ATOM   3234 C CA  . LYS B 2 430 ? 45.745  63.793  40.458 1.00 256.59 ? 430 LYS B CA  1 
ATOM   3235 C C   . LYS B 2 430 ? 45.322  63.231  41.823 1.00 297.86 ? 430 LYS B C   1 
ATOM   3236 O O   . LYS B 2 430 ? 44.393  62.426  41.918 1.00 368.10 ? 430 LYS B O   1 
ATOM   3237 C CB  . LYS B 2 430 ? 44.558  64.167  39.557 1.00 347.62 ? 430 LYS B CB  1 
ATOM   3238 C CG  . LYS B 2 430 ? 43.890  63.024  38.795 1.00 404.83 ? 430 LYS B CG  1 
ATOM   3239 C CD  . LYS B 2 430 ? 42.630  63.425  38.043 1.00 416.07 ? 430 LYS B CD  1 
ATOM   3240 C CE  . LYS B 2 430 ? 42.882  64.372  36.887 1.00 416.92 ? 430 LYS B CE  1 
ATOM   3241 N NZ  . LYS B 2 430 ? 41.643  64.653  36.120 1.00 444.93 ? 430 LYS B NZ  1 
ATOM   3242 N N   . VAL B 2 431 ? 46.012  63.675  42.887 1.00 296.23 ? 431 VAL B N   1 
ATOM   3243 C CA  . VAL B 2 431 ? 45.757  63.197  44.247 1.00 282.90 ? 431 VAL B CA  1 
ATOM   3244 C C   . VAL B 2 431 ? 44.466  63.815  44.801 1.00 263.80 ? 431 VAL B C   1 
ATOM   3245 O O   . VAL B 2 431 ? 44.057  64.912  44.414 1.00 267.13 ? 431 VAL B O   1 
ATOM   3246 C CB  . VAL B 2 431 ? 46.944  63.459  45.204 1.00 284.34 ? 431 VAL B CB  1 
ATOM   3247 C CG1 . VAL B 2 431 ? 48.241  62.889  44.645 1.00 270.73 ? 431 VAL B CG1 1 
ATOM   3248 C CG2 . VAL B 2 431 ? 47.131  64.934  45.575 1.00 266.83 ? 431 VAL B CG2 1 
ATOM   3249 N N   . ASN B 2 432 ? 43.833  63.090  45.735 1.00 219.38 ? 432 ASN B N   1 
ATOM   3250 C CA  . ASN B 2 432 ? 42.684  63.573  46.488 1.00 261.46 ? 432 ASN B CA  1 
ATOM   3251 C C   . ASN B 2 432 ? 43.034  64.874  47.227 1.00 208.28 ? 432 ASN B C   1 
ATOM   3252 O O   . ASN B 2 432 ? 44.035  64.925  47.927 1.00 205.87 ? 432 ASN B O   1 
ATOM   3253 C CB  . ASN B 2 432 ? 42.230  62.448  47.427 1.00 316.90 ? 432 ASN B CB  1 
ATOM   3254 C CG  . ASN B 2 432 ? 41.022  62.739  48.296 1.00 365.70 ? 432 ASN B CG  1 
ATOM   3255 O OD1 . ASN B 2 432 ? 40.510  63.855  48.345 1.00 414.54 ? 432 ASN B OD1 1 
ATOM   3256 N ND2 . ASN B 2 432 ? 40.552  61.721  49.003 1.00 344.63 ? 432 ASN B ND2 1 
ATOM   3257 N N   . LEU B 2 433 ? 42.187  65.913  47.115 1.00 204.03 ? 433 LEU B N   1 
ATOM   3258 C CA  . LEU B 2 433 ? 42.395  67.201  47.776 1.00 215.75 ? 433 LEU B CA  1 
ATOM   3259 C C   . LEU B 2 433 ? 42.545  67.054  49.303 1.00 236.11 ? 433 LEU B C   1 
ATOM   3260 O O   . LEU B 2 433 ? 43.206  67.887  49.927 1.00 167.65 ? 433 LEU B O   1 
ATOM   3261 C CB  . LEU B 2 433 ? 41.216  68.114  47.397 1.00 272.19 ? 433 LEU B CB  1 
ATOM   3262 C CG  . LEU B 2 433 ? 41.194  69.516  48.008 1.00 300.27 ? 433 LEU B CG  1 
ATOM   3263 C CD1 . LEU B 2 433 ? 42.425  70.305  47.597 1.00 241.42 ? 433 LEU B CD1 1 
ATOM   3264 C CD2 . LEU B 2 433 ? 39.921  70.253  47.613 1.00 338.32 ? 433 LEU B CD2 1 
ATOM   3265 N N   . ALA B 2 434 ? 41.946  66.001  49.904 1.00 330.15 ? 434 ALA B N   1 
ATOM   3266 C CA  . ALA B 2 434 ? 42.049  65.677  51.326 1.00 376.71 ? 434 ALA B CA  1 
ATOM   3267 C C   . ALA B 2 434 ? 43.490  65.503  51.843 1.00 336.79 ? 434 ALA B C   1 
ATOM   3268 O O   . ALA B 2 434 ? 43.699  65.624  53.055 1.00 396.55 ? 434 ALA B O   1 
ATOM   3269 C CB  . ALA B 2 434 ? 41.223  64.435  51.597 1.00 405.63 ? 434 ALA B CB  1 
ATOM   3270 N N   . LEU B 2 435 ? 44.477  65.227  50.968 1.00 247.60 ? 435 LEU B N   1 
ATOM   3271 C CA  . LEU B 2 435 ? 45.871  65.103  51.380 1.00 217.05 ? 435 LEU B CA  1 
ATOM   3272 C C   . LEU B 2 435 ? 46.516  66.495  51.522 1.00 198.18 ? 435 LEU B C   1 
ATOM   3273 O O   . LEU B 2 435 ? 46.863  66.875  52.646 1.00 181.91 ? 435 LEU B O   1 
ATOM   3274 C CB  . LEU B 2 435 ? 46.574  64.095  50.443 1.00 142.85 ? 435 LEU B CB  1 
ATOM   3275 C CG  . LEU B 2 435 ? 46.195  62.644  50.772 1.00 195.81 ? 435 LEU B CG  1 
ATOM   3276 C CD1 . LEU B 2 435 ? 46.314  61.729  49.570 1.00 205.91 ? 435 LEU B CD1 1 
ATOM   3277 C CD2 . LEU B 2 435 ? 47.029  62.067  51.919 1.00 242.65 ? 435 LEU B CD2 1 
ATOM   3278 N N   . PRO B 2 436 ? 46.719  67.310  50.456 1.00 169.20 ? 436 PRO B N   1 
ATOM   3279 C CA  . PRO B 2 436 ? 47.187  68.696  50.607 1.00 155.19 ? 436 PRO B CA  1 
ATOM   3280 C C   . PRO B 2 436 ? 46.488  69.552  51.669 1.00 167.28 ? 436 PRO B C   1 
ATOM   3281 O O   . PRO B 2 436 ? 47.192  70.303  52.327 1.00 219.14 ? 436 PRO B O   1 
ATOM   3282 C CB  . PRO B 2 436 ? 47.002  69.302  49.215 1.00 164.47 ? 436 PRO B CB  1 
ATOM   3283 C CG  . PRO B 2 436 ? 47.200  68.115  48.300 1.00 172.60 ? 436 PRO B CG  1 
ATOM   3284 C CD  . PRO B 2 436 ? 46.580  66.946  49.044 1.00 165.45 ? 436 PRO B CD  1 
ATOM   3285 N N   . VAL B 2 437 ? 45.168  69.456  51.889 1.00 174.96 ? 437 VAL B N   1 
ATOM   3286 C CA  . VAL B 2 437 ? 44.523  70.328  52.882 1.00 261.77 ? 437 VAL B CA  1 
ATOM   3287 C C   . VAL B 2 437 ? 44.870  69.952  54.336 1.00 290.78 ? 437 VAL B C   1 
ATOM   3288 O O   . VAL B 2 437 ? 44.654  70.768  55.233 1.00 292.29 ? 437 VAL B O   1 
ATOM   3289 C CB  . VAL B 2 437 ? 42.987  70.417  52.709 1.00 352.70 ? 437 VAL B CB  1 
ATOM   3290 C CG1 . VAL B 2 437 ? 42.617  70.998  51.353 1.00 323.75 ? 437 VAL B CG1 1 
ATOM   3291 C CG2 . VAL B 2 437 ? 42.265  69.093  52.961 1.00 375.09 ? 437 VAL B CG2 1 
ATOM   3292 N N   . PHE B 2 438 ? 45.384  68.739  54.597 1.00 288.71 ? 438 PHE B N   1 
ATOM   3293 C CA  . PHE B 2 438 ? 46.041  68.433  55.864 1.00 298.89 ? 438 PHE B CA  1 
ATOM   3294 C C   . PHE B 2 438 ? 47.509  68.860  55.822 1.00 246.20 ? 438 PHE B C   1 
ATOM   3295 O O   . PHE B 2 438 ? 48.002  69.472  56.774 1.00 265.35 ? 438 PHE B O   1 
ATOM   3296 C CB  . PHE B 2 438 ? 45.905  66.941  56.196 1.00 368.86 ? 438 PHE B CB  1 
ATOM   3297 C CG  . PHE B 2 438 ? 44.534  66.422  56.589 1.00 470.83 ? 438 PHE B CG  1 
ATOM   3298 C CD1 . PHE B 2 438 ? 43.411  67.246  56.720 1.00 500.68 ? 438 PHE B CD1 1 
ATOM   3299 C CD2 . PHE B 2 438 ? 44.370  65.061  56.842 1.00 491.71 ? 438 PHE B CD2 1 
ATOM   3300 C CE1 . PHE B 2 438 ? 42.175  66.719  57.086 1.00 473.80 ? 438 PHE B CE1 1 
ATOM   3301 C CE2 . PHE B 2 438 ? 43.134  64.538  57.208 1.00 493.62 ? 438 PHE B CE2 1 
ATOM   3302 C CZ  . PHE B 2 438 ? 42.039  65.367  57.330 1.00 486.11 ? 438 PHE B CZ  1 
ATOM   3303 N N   . PHE B 2 439 ? 48.208  68.535  54.725 1.00 222.57 ? 439 PHE B N   1 
ATOM   3304 C CA  . PHE B 2 439 ? 49.647  68.745  54.596 1.00 210.43 ? 439 PHE B CA  1 
ATOM   3305 C C   . PHE B 2 439 ? 50.057  70.233  54.643 1.00 167.44 ? 439 PHE B C   1 
ATOM   3306 O O   . PHE B 2 439 ? 51.015  70.573  55.327 1.00 144.29 ? 439 PHE B O   1 
ATOM   3307 C CB  . PHE B 2 439 ? 50.122  68.061  53.313 1.00 198.06 ? 439 PHE B CB  1 
ATOM   3308 C CG  . PHE B 2 439 ? 51.617  68.054  53.139 1.00 197.85 ? 439 PHE B CG  1 
ATOM   3309 C CD1 . PHE B 2 439 ? 52.385  67.070  53.726 1.00 166.33 ? 439 PHE B CD1 1 
ATOM   3310 C CD2 . PHE B 2 439 ? 52.258  69.056  52.408 1.00 243.12 ? 439 PHE B CD2 1 
ATOM   3311 C CE1 . PHE B 2 439 ? 53.770  67.090  53.588 1.00 193.89 ? 439 PHE B CE1 1 
ATOM   3312 C CE2 . PHE B 2 439 ? 53.639  69.067  52.251 1.00 178.77 ? 439 PHE B CE2 1 
ATOM   3313 C CZ  . PHE B 2 439 ? 54.396  68.082  52.849 1.00 187.01 ? 439 PHE B CZ  1 
ATOM   3314 N N   . ILE B 2 440 ? 49.361  71.131  53.934 1.00 165.38 ? 440 ILE B N   1 
ATOM   3315 C CA  . ILE B 2 440 ? 49.626  72.568  53.986 1.00 168.46 ? 440 ILE B CA  1 
ATOM   3316 C C   . ILE B 2 440 ? 49.502  73.055  55.432 1.00 210.25 ? 440 ILE B C   1 
ATOM   3317 O O   . ILE B 2 440 ? 50.346  73.815  55.900 1.00 209.08 ? 440 ILE B O   1 
ATOM   3318 C CB  . ILE B 2 440 ? 48.665  73.349  53.057 1.00 279.38 ? 440 ILE B CB  1 
ATOM   3319 C CG1 . ILE B 2 440 ? 48.943  73.084  51.580 1.00 285.40 ? 440 ILE B CG1 1 
ATOM   3320 C CG2 . ILE B 2 440 ? 48.688  74.857  53.327 1.00 309.47 ? 440 ILE B CG2 1 
ATOM   3321 C CD1 . ILE B 2 440 ? 47.821  73.504  50.652 1.00 311.70 ? 440 ILE B CD1 1 
ATOM   3322 N N   . LEU B 2 441 ? 48.452  72.621  56.146 1.00 248.20 ? 441 LEU B N   1 
ATOM   3323 C CA  . LEU B 2 441 ? 48.269  72.985  57.549 1.00 284.69 ? 441 LEU B CA  1 
ATOM   3324 C C   . LEU B 2 441 ? 49.389  72.414  58.433 1.00 250.40 ? 441 LEU B C   1 
ATOM   3325 O O   . LEU B 2 441 ? 49.782  73.049  59.404 1.00 212.77 ? 441 LEU B O   1 
ATOM   3326 C CB  . LEU B 2 441 ? 46.873  72.548  58.011 1.00 345.54 ? 441 LEU B CB  1 
ATOM   3327 C CG  . LEU B 2 441 ? 45.765  73.578  57.802 1.00 425.91 ? 441 LEU B CG  1 
ATOM   3328 C CD1 . LEU B 2 441 ? 45.621  73.999  56.343 1.00 422.63 ? 441 LEU B CD1 1 
ATOM   3329 C CD2 . LEU B 2 441 ? 44.446  73.031  58.319 1.00 487.72 ? 441 LEU B CD2 1 
ATOM   3330 N N   . ALA B 2 442 ? 49.926  71.231  58.110 1.00 228.92 ? 442 ALA B N   1 
ATOM   3331 C CA  . ALA B 2 442 ? 51.065  70.663  58.820 1.00 219.61 ? 442 ALA B CA  1 
ATOM   3332 C C   . ALA B 2 442 ? 52.347  71.481  58.590 1.00 224.91 ? 442 ALA B C   1 
ATOM   3333 O O   . ALA B 2 442 ? 53.091  71.729  59.543 1.00 302.86 ? 442 ALA B O   1 
ATOM   3334 C CB  . ALA B 2 442 ? 51.208  69.208  58.437 1.00 259.33 ? 442 ALA B CB  1 
ATOM   3335 N N   . CYS B 2 443 ? 52.622  71.935  57.360 1.00 238.19 ? 443 CYS B N   1 
ATOM   3336 C CA  . CYS B 2 443 ? 53.713  72.876  57.105 1.00 255.79 ? 443 CYS B CA  1 
ATOM   3337 C C   . CYS B 2 443 ? 53.531  74.178  57.900 1.00 190.04 ? 443 CYS B C   1 
ATOM   3338 O O   . CYS B 2 443 ? 54.462  74.666  58.536 1.00 165.50 ? 443 CYS B O   1 
ATOM   3339 C CB  . CYS B 2 443 ? 53.827  73.196  55.617 1.00 277.93 ? 443 CYS B CB  1 
ATOM   3340 S SG  . CYS B 2 443 ? 54.215  71.754  54.593 1.00 220.58 ? 443 CYS B SG  1 
ATOM   3341 N N   . LEU B 2 444 ? 52.320  74.737  57.884 1.00 205.51 ? 444 LEU B N   1 
ATOM   3342 C CA  . LEU B 2 444 ? 52.018  75.952  58.627 1.00 273.70 ? 444 LEU B CA  1 
ATOM   3343 C C   . LEU B 2 444 ? 52.175  75.720  60.135 1.00 232.93 ? 444 LEU B C   1 
ATOM   3344 O O   . LEU B 2 444 ? 52.688  76.594  60.820 1.00 191.74 ? 444 LEU B O   1 
ATOM   3345 C CB  . LEU B 2 444 ? 50.609  76.438  58.247 1.00 317.57 ? 444 LEU B CB  1 
ATOM   3346 C CG  . LEU B 2 444 ? 50.471  76.985  56.827 1.00 330.93 ? 444 LEU B CG  1 
ATOM   3347 C CD1 . LEU B 2 444 ? 49.007  77.149  56.449 1.00 361.60 ? 444 LEU B CD1 1 
ATOM   3348 C CD2 . LEU B 2 444 ? 51.204  78.314  56.675 1.00 326.43 ? 444 LEU B CD2 1 
ATOM   3349 N N   . PHE B 2 445 ? 51.763  74.561  60.664 1.00 177.70 ? 445 PHE B N   1 
ATOM   3350 C CA  . PHE B 2 445 ? 51.886  74.234  62.078 1.00 208.92 ? 445 PHE B CA  1 
ATOM   3351 C C   . PHE B 2 445 ? 53.346  74.309  62.531 1.00 195.02 ? 445 PHE B C   1 
ATOM   3352 O O   . PHE B 2 445 ? 53.660  74.983  63.507 1.00 224.31 ? 445 PHE B O   1 
ATOM   3353 C CB  . PHE B 2 445 ? 51.239  72.867  62.337 1.00 232.61 ? 445 PHE B CB  1 
ATOM   3354 C CG  . PHE B 2 445 ? 51.564  72.220  63.663 1.00 276.49 ? 445 PHE B CG  1 
ATOM   3355 C CD1 . PHE B 2 445 ? 51.293  72.870  64.862 1.00 277.17 ? 445 PHE B CD1 1 
ATOM   3356 C CD2 . PHE B 2 445 ? 52.140  70.955  63.717 1.00 307.22 ? 445 PHE B CD2 1 
ATOM   3357 C CE1 . PHE B 2 445 ? 51.593  72.274  66.082 1.00 282.55 ? 445 PHE B CE1 1 
ATOM   3358 C CE2 . PHE B 2 445 ? 52.436  70.356  64.936 1.00 314.10 ? 445 PHE B CE2 1 
ATOM   3359 C CZ  . PHE B 2 445 ? 52.165  71.019  66.116 1.00 317.12 ? 445 PHE B CZ  1 
ATOM   3360 N N   . LEU B 2 446 ? 54.243  73.619  61.820 1.00 180.39 ? 446 LEU B N   1 
ATOM   3361 C CA  . LEU B 2 446 ? 55.679  73.631  62.110 1.00 158.27 ? 446 LEU B CA  1 
ATOM   3362 C C   . LEU B 2 446 ? 56.254  75.050  62.104 1.00 173.98 ? 446 LEU B C   1 
ATOM   3363 O O   . LEU B 2 446 ? 56.928  75.430  63.051 1.00 201.59 ? 446 LEU B O   1 
ATOM   3364 C CB  . LEU B 2 446 ? 56.403  72.718  61.112 1.00 145.79 ? 446 LEU B CB  1 
ATOM   3365 C CG  . LEU B 2 446 ? 56.707  71.299  61.620 1.00 144.55 ? 446 LEU B CG  1 
ATOM   3366 C CD1 . LEU B 2 446 ? 55.475  70.573  62.156 1.00 157.30 ? 446 LEU B CD1 1 
ATOM   3367 C CD2 . LEU B 2 446 ? 57.325  70.450  60.523 1.00 152.36 ? 446 LEU B CD2 1 
ATOM   3368 N N   . ILE B 2 447 ? 55.970  75.828  61.056 1.00 181.07 ? 447 ILE B N   1 
ATOM   3369 C CA  . ILE B 2 447 ? 56.449  77.204  60.928 1.00 229.24 ? 447 ILE B CA  1 
ATOM   3370 C C   . ILE B 2 447 ? 55.889  78.082  62.064 1.00 226.67 ? 447 ILE B C   1 
ATOM   3371 O O   . ILE B 2 447 ? 56.651  78.780  62.738 1.00 188.26 ? 447 ILE B O   1 
ATOM   3372 C CB  . ILE B 2 447 ? 56.152  77.744  59.502 1.00 227.82 ? 447 ILE B CB  1 
ATOM   3373 C CG1 . ILE B 2 447 ? 57.277  77.404  58.524 1.00 247.83 ? 447 ILE B CG1 1 
ATOM   3374 C CG2 . ILE B 2 447 ? 55.923  79.257  59.457 1.00 253.97 ? 447 ILE B CG2 1 
ATOM   3375 C CD1 . ILE B 2 447 ? 57.742  75.969  58.510 1.00 295.36 ? 447 ILE B CD1 1 
ATOM   3376 N N   . ALA B 2 448 ? 54.569  78.033  62.285 1.00 206.91 ? 448 ALA B N   1 
ATOM   3377 C CA  . ALA B 2 448 ? 53.876  78.919  63.211 1.00 253.16 ? 448 ALA B CA  1 
ATOM   3378 C C   . ALA B 2 448 ? 54.370  78.736  64.650 1.00 241.44 ? 448 ALA B C   1 
ATOM   3379 O O   . ALA B 2 448 ? 54.526  79.732  65.361 1.00 291.50 ? 448 ALA B O   1 
ATOM   3380 C CB  . ALA B 2 448 ? 52.376  78.708  63.098 1.00 293.88 ? 448 ALA B CB  1 
ATOM   3381 N N   . VAL B 2 449 ? 54.619  77.492  65.087 1.00 210.25 ? 449 VAL B N   1 
ATOM   3382 C CA  . VAL B 2 449 ? 55.225  77.236  66.392 1.00 229.36 ? 449 VAL B CA  1 
ATOM   3383 C C   . VAL B 2 449 ? 56.651  77.788  66.433 1.00 188.19 ? 449 VAL B C   1 
ATOM   3384 O O   . VAL B 2 449 ? 57.041  78.437  67.413 1.00 171.23 ? 449 VAL B O   1 
ATOM   3385 C CB  . VAL B 2 449 ? 55.169  75.738  66.740 1.00 231.52 ? 449 VAL B CB  1 
ATOM   3386 C CG1 . VAL B 2 449 ? 56.016  75.378  67.955 1.00 253.77 ? 449 VAL B CG1 1 
ATOM   3387 C CG2 . VAL B 2 449 ? 53.729  75.299  66.963 1.00 230.31 ? 449 VAL B CG2 1 
ATOM   3388 N N   . SER B 2 450 ? 57.415  77.533  65.363 1.00 180.07 ? 450 SER B N   1 
ATOM   3389 C CA  . SER B 2 450 ? 58.842  77.835  65.308 1.00 202.39 ? 450 SER B CA  1 
ATOM   3390 C C   . SER B 2 450 ? 59.168  79.329  65.343 1.00 185.65 ? 450 SER B C   1 
ATOM   3391 O O   . SER B 2 450 ? 60.234  79.678  65.831 1.00 149.90 ? 450 SER B O   1 
ATOM   3392 C CB  . SER B 2 450 ? 59.463  77.197  64.103 1.00 179.25 ? 450 SER B CB  1 
ATOM   3393 O OG  . SER B 2 450 ? 59.250  75.804  64.189 1.00 211.55 ? 450 SER B OG  1 
ATOM   3394 N N   . PHE B 2 451 ? 58.285  80.205  64.847 1.00 200.98 ? 451 PHE B N   1 
ATOM   3395 C CA  . PHE B 2 451 ? 58.450  81.653  64.980 1.00 238.88 ? 451 PHE B CA  1 
ATOM   3396 C C   . PHE B 2 451 ? 58.750  82.087  66.420 1.00 288.18 ? 451 PHE B C   1 
ATOM   3397 O O   . PHE B 2 451 ? 59.562  82.987  66.607 1.00 231.77 ? 451 PHE B O   1 
ATOM   3398 C CB  . PHE B 2 451 ? 57.192  82.386  64.491 1.00 264.61 ? 451 PHE B CB  1 
ATOM   3399 C CG  . PHE B 2 451 ? 57.212  82.832  63.050 1.00 274.42 ? 451 PHE B CG  1 
ATOM   3400 C CD1 . PHE B 2 451 ? 58.010  83.908  62.671 1.00 251.96 ? 451 PHE B CD1 1 
ATOM   3401 C CD2 . PHE B 2 451 ? 56.437  82.190  62.079 1.00 317.39 ? 451 PHE B CD2 1 
ATOM   3402 C CE1 . PHE B 2 451 ? 58.036  84.334  61.347 1.00 328.59 ? 451 PHE B CE1 1 
ATOM   3403 C CE2 . PHE B 2 451 ? 56.467  82.620  60.756 1.00 339.09 ? 451 PHE B CE2 1 
ATOM   3404 C CZ  . PHE B 2 451 ? 57.265  83.691  60.393 1.00 345.82 ? 451 PHE B CZ  1 
ATOM   3405 N N   . TRP B 2 452 ? 58.090  81.460  67.418 1.00 349.86 ? 452 TRP B N   1 
ATOM   3406 C CA  . TRP B 2 452 ? 58.235  81.807  68.832 1.00 344.42 ? 452 TRP B CA  1 
ATOM   3407 C C   . TRP B 2 452 ? 59.070  80.787  69.620 1.00 309.50 ? 452 TRP B C   1 
ATOM   3408 O O   . TRP B 2 452 ? 59.679  81.169  70.619 1.00 329.22 ? 452 TRP B O   1 
ATOM   3409 C CB  . TRP B 2 452 ? 56.843  82.051  69.444 1.00 321.36 ? 452 TRP B CB  1 
ATOM   3410 C CG  . TRP B 2 452 ? 56.153  83.233  68.811 1.00 323.38 ? 452 TRP B CG  1 
ATOM   3411 C CD1 . TRP B 2 452 ? 56.508  84.534  68.998 1.00 300.39 ? 452 TRP B CD1 1 
ATOM   3412 C CD2 . TRP B 2 452 ? 55.028  83.250  67.886 1.00 343.25 ? 452 TRP B CD2 1 
ATOM   3413 N NE1 . TRP B 2 452 ? 55.685  85.359  68.273 1.00 327.48 ? 452 TRP B NE1 1 
ATOM   3414 C CE2 . TRP B 2 452 ? 54.765  84.609  67.576 1.00 362.30 ? 452 TRP B CE2 1 
ATOM   3415 C CE3 . TRP B 2 452 ? 54.212  82.271  67.289 1.00 345.59 ? 452 TRP B CE3 1 
ATOM   3416 C CZ2 . TRP B 2 452 ? 53.730  84.994  66.703 1.00 383.09 ? 452 TRP B CZ2 1 
ATOM   3417 C CZ3 . TRP B 2 452 ? 53.192  82.648  66.430 1.00 355.39 ? 452 TRP B CZ3 1 
ATOM   3418 C CH2 . TRP B 2 452 ? 52.956  83.996  66.140 1.00 364.26 ? 452 TRP B CH2 1 
ATOM   3419 N N   . LYS B 2 453 ? 59.148  79.513  69.195 1.00 271.72 ? 453 LYS B N   1 
ATOM   3420 C CA  . LYS B 2 453 ? 60.030  78.546  69.851 1.00 246.14 ? 453 LYS B CA  1 
ATOM   3421 C C   . LYS B 2 453 ? 61.511  78.791  69.518 1.00 219.69 ? 453 LYS B C   1 
ATOM   3422 O O   . LYS B 2 453 ? 62.366  78.560  70.376 1.00 210.65 ? 453 LYS B O   1 
ATOM   3423 C CB  . LYS B 2 453 ? 59.651  77.096  69.522 1.00 207.84 ? 453 LYS B CB  1 
ATOM   3424 C CG  . LYS B 2 453 ? 59.525  76.197  70.744 1.00 240.44 ? 453 LYS B CG  1 
ATOM   3425 C CD  . LYS B 2 453 ? 60.710  76.164  71.707 1.00 246.05 ? 453 LYS B CD  1 
ATOM   3426 C CE  . LYS B 2 453 ? 60.442  75.299  72.921 1.00 241.97 ? 453 LYS B CE  1 
ATOM   3427 N NZ  . LYS B 2 453 ? 61.462  75.495  73.977 1.00 260.68 ? 453 LYS B NZ  1 
ATOM   3428 N N   . THR B 2 454 ? 61.817  79.264  68.295 1.00 214.46 ? 454 THR B N   1 
ATOM   3429 C CA  . THR B 2 454 ? 63.185  79.525  67.842 1.00 246.65 ? 454 THR B CA  1 
ATOM   3430 C C   . THR B 2 454 ? 63.246  80.849  67.071 1.00 208.24 ? 454 THR B C   1 
ATOM   3431 O O   . THR B 2 454 ? 63.450  80.851  65.854 1.00 327.46 ? 454 THR B O   1 
ATOM   3432 C CB  . THR B 2 454 ? 63.726  78.353  67.001 1.00 296.80 ? 454 THR B CB  1 
ATOM   3433 O OG1 . THR B 2 454 ? 62.855  78.061  65.908 1.00 232.08 ? 454 THR B OG1 1 
ATOM   3434 C CG2 . THR B 2 454 ? 63.907  77.083  67.802 1.00 346.36 ? 454 THR B CG2 1 
ATOM   3435 N N   . PRO B 2 455 ? 63.059  82.015  67.729 1.00 163.40 ? 455 PRO B N   1 
ATOM   3436 C CA  . PRO B 2 455 ? 62.969  83.288  67.013 1.00 186.89 ? 455 PRO B CA  1 
ATOM   3437 C C   . PRO B 2 455 ? 64.247  83.750  66.305 1.00 179.81 ? 455 PRO B C   1 
ATOM   3438 O O   . PRO B 2 455 ? 64.152  84.240  65.177 1.00 232.52 ? 455 PRO B O   1 
ATOM   3439 C CB  . PRO B 2 455 ? 62.601  84.300  68.122 1.00 298.32 ? 455 PRO B CB  1 
ATOM   3440 C CG  . PRO B 2 455 ? 62.087  83.455  69.275 1.00 279.37 ? 455 PRO B CG  1 
ATOM   3441 C CD  . PRO B 2 455 ? 62.898  82.180  69.181 1.00 213.96 ? 455 PRO B CD  1 
ATOM   3442 N N   . VAL B 2 456 ? 65.429  83.596  66.937 1.00 149.47 ? 456 VAL B N   1 
ATOM   3443 C CA  . VAL B 2 456 ? 66.644  84.274  66.477 1.00 201.14 ? 456 VAL B CA  1 
ATOM   3444 C C   . VAL B 2 456 ? 67.149  83.686  65.147 1.00 226.39 ? 456 VAL B C   1 
ATOM   3445 O O   . VAL B 2 456 ? 67.646  84.430  64.295 1.00 171.85 ? 456 VAL B O   1 
ATOM   3446 C CB  . VAL B 2 456 ? 67.741  84.282  67.568 1.00 260.19 ? 456 VAL B CB  1 
ATOM   3447 C CG1 . VAL B 2 456 ? 68.270  82.894  67.934 1.00 279.52 ? 456 VAL B CG1 1 
ATOM   3448 C CG2 . VAL B 2 456 ? 68.894  85.202  67.180 1.00 273.66 ? 456 VAL B CG2 1 
ATOM   3449 N N   . GLU B 2 457 ? 67.015  82.361  64.963 1.00 250.05 ? 457 GLU B N   1 
ATOM   3450 C CA  . GLU B 2 457 ? 67.355  81.690  63.710 1.00 252.99 ? 457 GLU B CA  1 
ATOM   3451 C C   . GLU B 2 457 ? 66.449  82.174  62.566 1.00 196.46 ? 457 GLU B C   1 
ATOM   3452 O O   . GLU B 2 457 ? 66.912  82.498  61.467 1.00 248.07 ? 457 GLU B O   1 
ATOM   3453 C CB  . GLU B 2 457 ? 67.301  80.165  63.891 1.00 272.68 ? 457 GLU B CB  1 
ATOM   3454 C CG  . GLU B 2 457 ? 68.392  79.591  64.819 1.00 314.52 ? 457 GLU B CG  1 
ATOM   3455 C CD  . GLU B 2 457 ? 69.822  79.601  64.288 1.00 372.97 ? 457 GLU B CD  1 
ATOM   3456 O OE1 . GLU B 2 457 ? 70.072  80.222  63.226 1.00 355.49 ? 457 GLU B OE1 1 
ATOM   3457 O OE2 . GLU B 2 457 ? 70.696  78.955  64.930 1.00 409.78 ? 457 GLU B OE2 1 
ATOM   3458 N N   . CYS B 2 458 ? 65.145  82.249  62.797 1.00 165.82 ? 458 CYS B N   1 
ATOM   3459 C CA  . CYS B 2 458 ? 64.229  82.830  61.815 1.00 197.54 ? 458 CYS B CA  1 
ATOM   3460 C C   . CYS B 2 458 ? 64.565  84.299  61.512 1.00 174.72 ? 458 CYS B C   1 
ATOM   3461 O O   . CYS B 2 458 ? 64.487  84.715  60.371 1.00 183.60 ? 458 CYS B O   1 
ATOM   3462 C CB  . CYS B 2 458 ? 62.786  82.687  62.278 1.00 203.92 ? 458 CYS B CB  1 
ATOM   3463 S SG  . CYS B 2 458 ? 62.441  80.962  62.655 1.00 241.74 ? 458 CYS B SG  1 
ATOM   3464 N N   . GLY B 2 459 ? 64.950  85.093  62.506 1.00 166.74 ? 459 GLY B N   1 
ATOM   3465 C CA  . GLY B 2 459 ? 65.303  86.484  62.300 1.00 230.23 ? 459 GLY B CA  1 
ATOM   3466 C C   . GLY B 2 459 ? 66.471  86.675  61.335 1.00 211.15 ? 459 GLY B C   1 
ATOM   3467 O O   . GLY B 2 459 ? 66.367  87.485  60.410 1.00 226.27 ? 459 GLY B O   1 
ATOM   3468 N N   . ILE B 2 460 ? 67.578  85.942  61.539 1.00 183.59 ? 460 ILE B N   1 
ATOM   3469 C CA  . ILE B 2 460 ? 68.724  86.042  60.638 1.00 203.82 ? 460 ILE B CA  1 
ATOM   3470 C C   . ILE B 2 460 ? 68.367  85.455  59.263 1.00 177.40 ? 460 ILE B C   1 
ATOM   3471 O O   . ILE B 2 460 ? 68.799  85.986  58.238 1.00 237.38 ? 460 ILE B O   1 
ATOM   3472 C CB  . ILE B 2 460 ? 70.005  85.457  61.280 1.00 205.52 ? 460 ILE B CB  1 
ATOM   3473 C CG1 . ILE B 2 460 ? 71.279  85.782  60.480 1.00 268.64 ? 460 ILE B CG1 1 
ATOM   3474 C CG2 . ILE B 2 460 ? 69.892  83.971  61.516 1.00 168.71 ? 460 ILE B CG2 1 
ATOM   3475 C CD1 . ILE B 2 460 ? 71.648  87.250  60.408 1.00 276.89 ? 460 ILE B CD1 1 
ATOM   3476 N N   . GLY B 2 461 ? 67.539  84.412  59.205 1.00 156.52 ? 461 GLY B N   1 
ATOM   3477 C CA  . GLY B 2 461 ? 67.073  83.889  57.930 1.00 169.59 ? 461 GLY B CA  1 
ATOM   3478 C C   . GLY B 2 461 ? 66.170  84.847  57.148 1.00 174.53 ? 461 GLY B C   1 
ATOM   3479 O O   . GLY B 2 461 ? 66.382  85.040  55.963 1.00 143.35 ? 461 GLY B O   1 
ATOM   3480 N N   . PHE B 2 462 ? 65.161  85.470  57.774 1.00 180.94 ? 462 PHE B N   1 
ATOM   3481 C CA  . PHE B 2 462 ? 64.370  86.499  57.111 1.00 164.36 ? 462 PHE B CA  1 
ATOM   3482 C C   . PHE B 2 462 ? 65.233  87.712  56.757 1.00 165.82 ? 462 PHE B C   1 
ATOM   3483 O O   . PHE B 2 462 ? 64.924  88.372  55.775 1.00 192.53 ? 462 PHE B O   1 
ATOM   3484 C CB  . PHE B 2 462 ? 63.138  86.856  57.950 1.00 186.33 ? 462 PHE B CB  1 
ATOM   3485 C CG  . PHE B 2 462 ? 62.037  85.827  57.854 1.00 203.19 ? 462 PHE B CG  1 
ATOM   3486 C CD1 . PHE B 2 462 ? 61.399  85.586  56.641 1.00 235.90 ? 462 PHE B CD1 1 
ATOM   3487 C CD2 . PHE B 2 462 ? 61.632  85.092  58.962 1.00 217.68 ? 462 PHE B CD2 1 
ATOM   3488 C CE1 . PHE B 2 462 ? 60.383  84.643  56.535 1.00 261.41 ? 462 PHE B CE1 1 
ATOM   3489 C CE2 . PHE B 2 462 ? 60.614  84.147  58.859 1.00 285.08 ? 462 PHE B CE2 1 
ATOM   3490 C CZ  . PHE B 2 462 ? 59.992  83.918  57.642 1.00 296.86 ? 462 PHE B CZ  1 
ATOM   3491 N N   . THR B 2 463 ? 66.306  88.015  57.502 1.00 164.20 ? 463 THR B N   1 
ATOM   3492 C CA  . THR B 2 463 ? 67.277  89.033  57.092 1.00 179.16 ? 463 THR B CA  1 
ATOM   3493 C C   . THR B 2 463 ? 67.970  88.662  55.771 1.00 143.91 ? 463 THR B C   1 
ATOM   3494 O O   . THR B 2 463 ? 68.147  89.531  54.921 1.00 201.03 ? 463 THR B O   1 
ATOM   3495 C CB  . THR B 2 463 ? 68.280  89.335  58.217 1.00 236.60 ? 463 THR B CB  1 
ATOM   3496 O OG1 . THR B 2 463 ? 67.534  89.784  59.356 1.00 257.94 ? 463 THR B OG1 1 
ATOM   3497 C CG2 . THR B 2 463 ? 69.338  90.355  57.842 1.00 268.56 ? 463 THR B CG2 1 
ATOM   3498 N N   . ILE B 2 464 ? 68.319  87.385  55.559 1.00 163.81 ? 464 ILE B N   1 
ATOM   3499 C CA  . ILE B 2 464 ? 68.795  86.895  54.261 1.00 177.24 ? 464 ILE B CA  1 
ATOM   3500 C C   . ILE B 2 464 ? 67.728  87.061  53.163 1.00 172.87 ? 464 ILE B C   1 
ATOM   3501 O O   . ILE B 2 464 ? 68.051  87.563  52.092 1.00 172.41 ? 464 ILE B O   1 
ATOM   3502 C CB  . ILE B 2 464 ? 69.295  85.434  54.356 1.00 162.16 ? 464 ILE B CB  1 
ATOM   3503 C CG1 . ILE B 2 464 ? 70.512  85.327  55.270 1.00 196.51 ? 464 ILE B CG1 1 
ATOM   3504 C CG2 . ILE B 2 464 ? 69.594  84.831  52.984 1.00 177.71 ? 464 ILE B CG2 1 
ATOM   3505 C CD1 . ILE B 2 464 ? 70.733  83.940  55.813 1.00 206.52 ? 464 ILE B CD1 1 
ATOM   3506 N N   . ILE B 2 465 ? 66.471  86.672  53.419 1.00 138.69 ? 465 ILE B N   1 
ATOM   3507 C CA  . ILE B 2 465 ? 65.396  86.781  52.439 1.00 167.52 ? 465 ILE B CA  1 
ATOM   3508 C C   . ILE B 2 465 ? 65.196  88.244  52.034 1.00 212.36 ? 465 ILE B C   1 
ATOM   3509 O O   . ILE B 2 465 ? 65.186  88.530  50.834 1.00 247.96 ? 465 ILE B O   1 
ATOM   3510 C CB  . ILE B 2 465 ? 64.089  86.141  52.965 1.00 201.73 ? 465 ILE B CB  1 
ATOM   3511 C CG1 . ILE B 2 465 ? 64.267  84.626  53.049 1.00 244.12 ? 465 ILE B CG1 1 
ATOM   3512 C CG2 . ILE B 2 465 ? 62.853  86.518  52.130 1.00 205.68 ? 465 ILE B CG2 1 
ATOM   3513 C CD1 . ILE B 2 465 ? 63.159  83.885  53.746 1.00 264.20 ? 465 ILE B CD1 1 
ATOM   3514 N N   . LEU B 2 466 ? 65.049  89.165  53.004 1.00 182.08 ? 466 LEU B N   1 
ATOM   3515 C CA  . LEU B 2 466 ? 64.839  90.579  52.704 1.00 180.19 ? 466 LEU B CA  1 
ATOM   3516 C C   . LEU B 2 466 ? 66.051  91.176  51.977 1.00 181.72 ? 466 LEU B C   1 
ATOM   3517 O O   . LEU B 2 466 ? 65.856  92.035  51.118 1.00 254.55 ? 466 LEU B O   1 
ATOM   3518 C CB  . LEU B 2 466 ? 64.474  91.336  53.988 1.00 194.62 ? 466 LEU B CB  1 
ATOM   3519 C CG  . LEU B 2 466 ? 63.143  90.929  54.635 1.00 255.25 ? 466 LEU B CG  1 
ATOM   3520 C CD1 . LEU B 2 466 ? 62.961  91.648  55.960 1.00 322.17 ? 466 LEU B CD1 1 
ATOM   3521 C CD2 . LEU B 2 466 ? 61.934  91.181  53.738 1.00 287.96 ? 466 LEU B CD2 1 
ATOM   3522 N N   . SER B 2 467 ? 67.281  90.715  52.256 1.00 159.68 ? 467 SER B N   1 
ATOM   3523 C CA  . SER B 2 467 ? 68.466  91.112  51.484 1.00 200.10 ? 467 SER B CA  1 
ATOM   3524 C C   . SER B 2 467 ? 68.454  90.622  50.027 1.00 178.04 ? 467 SER B C   1 
ATOM   3525 O O   . SER B 2 467 ? 69.284  91.052  49.234 1.00 191.57 ? 467 SER B O   1 
ATOM   3526 C CB  . SER B 2 467 ? 69.750  90.694  52.161 1.00 265.85 ? 467 SER B CB  1 
ATOM   3527 O OG  . SER B 2 467 ? 70.074  89.341  51.900 1.00 258.78 ? 467 SER B OG  1 
ATOM   3528 N N   . GLY B 2 468 ? 67.520  89.748  49.649 1.00 177.92 ? 468 GLY B N   1 
ATOM   3529 C CA  . GLY B 2 468 ? 67.290  89.376  48.259 1.00 197.45 ? 468 GLY B CA  1 
ATOM   3530 C C   . GLY B 2 468 ? 66.535  90.408  47.422 1.00 186.03 ? 468 GLY B C   1 
ATOM   3531 O O   . GLY B 2 468 ? 66.660  90.414  46.200 1.00 156.91 ? 468 GLY B O   1 
ATOM   3532 N N   . LEU B 2 469 ? 65.768  91.308  48.055 1.00 190.24 ? 469 LEU B N   1 
ATOM   3533 C CA  . LEU B 2 469 ? 64.955  92.265  47.313 1.00 172.40 ? 469 LEU B CA  1 
ATOM   3534 C C   . LEU B 2 469 ? 65.856  93.272  46.579 1.00 173.90 ? 469 LEU B C   1 
ATOM   3535 O O   . LEU B 2 469 ? 65.625  93.507  45.394 1.00 176.48 ? 469 LEU B O   1 
ATOM   3536 C CB  . LEU B 2 469 ? 63.935  92.920  48.262 1.00 162.65 ? 469 LEU B CB  1 
ATOM   3537 C CG  . LEU B 2 469 ? 62.971  91.959  48.957 1.00 191.02 ? 469 LEU B CG  1 
ATOM   3538 C CD1 . LEU B 2 469 ? 62.019  92.711  49.874 1.00 243.26 ? 469 LEU B CD1 1 
ATOM   3539 C CD2 . LEU B 2 469 ? 62.177  91.161  47.941 1.00 179.00 ? 469 LEU B CD2 1 
ATOM   3540 N N   . PRO B 2 470 ? 66.896  93.901  47.198 1.00 170.94 ? 470 PRO B N   1 
ATOM   3541 C CA  . PRO B 2 470 ? 67.885  94.701  46.469 1.00 238.79 ? 470 PRO B CA  1 
ATOM   3542 C C   . PRO B 2 470 ? 68.460  94.042  45.221 1.00 181.35 ? 470 PRO B C   1 
ATOM   3543 O O   . PRO B 2 470 ? 68.394  94.639  44.148 1.00 214.74 ? 470 PRO B O   1 
ATOM   3544 C CB  . PRO B 2 470 ? 68.992  94.933  47.516 1.00 248.97 ? 470 PRO B CB  1 
ATOM   3545 C CG  . PRO B 2 470 ? 68.185  95.080  48.781 1.00 238.94 ? 470 PRO B CG  1 
ATOM   3546 C CD  . PRO B 2 470 ? 67.195  93.945  48.630 1.00 166.29 ? 470 PRO B CD  1 
ATOM   3547 N N   . VAL B 2 471 ? 69.001  92.829  45.352 1.00 149.17 ? 471 VAL B N   1 
ATOM   3548 C CA  . VAL B 2 471 ? 69.623  92.150  44.209 1.00 196.46 ? 471 VAL B CA  1 
ATOM   3549 C C   . VAL B 2 471 ? 68.599  91.680  43.166 1.00 184.36 ? 471 VAL B C   1 
ATOM   3550 O O   . VAL B 2 471 ? 68.972  91.553  42.000 1.00 182.69 ? 471 VAL B O   1 
ATOM   3551 C CB  . VAL B 2 471 ? 70.564  91.008  44.632 1.00 177.79 ? 471 VAL B CB  1 
ATOM   3552 C CG1 . VAL B 2 471 ? 71.842  91.593  45.218 1.00 206.27 ? 471 VAL B CG1 1 
ATOM   3553 C CG2 . VAL B 2 471 ? 69.895  90.012  45.565 1.00 169.94 ? 471 VAL B CG2 1 
ATOM   3554 N N   . TYR B 2 472 ? 67.332  91.455  43.536 1.00 186.51 ? 472 TYR B N   1 
ATOM   3555 C CA  . TYR B 2 472 ? 66.287  91.230  42.542 1.00 200.84 ? 472 TYR B CA  1 
ATOM   3556 C C   . TYR B 2 472 ? 66.048  92.492  41.698 1.00 205.53 ? 472 TYR B C   1 
ATOM   3557 O O   . TYR B 2 472 ? 66.022  92.428  40.465 1.00 181.99 ? 472 TYR B O   1 
ATOM   3558 C CB  . TYR B 2 472 ? 64.984  90.762  43.206 1.00 251.60 ? 472 TYR B CB  1 
ATOM   3559 C CG  . TYR B 2 472 ? 63.908  90.540  42.151 1.00 204.08 ? 472 TYR B CG  1 
ATOM   3560 C CD1 . TYR B 2 472 ? 64.049  89.496  41.227 1.00 176.50 ? 472 TYR B CD1 1 
ATOM   3561 C CD2 . TYR B 2 472 ? 62.786  91.369  42.072 1.00 188.99 ? 472 TYR B CD2 1 
ATOM   3562 C CE1 . TYR B 2 472 ? 63.091  89.281  40.249 1.00 176.37 ? 472 TYR B CE1 1 
ATOM   3563 C CE2 . TYR B 2 472 ? 61.833  91.160  41.084 1.00 269.25 ? 472 TYR B CE2 1 
ATOM   3564 C CZ  . TYR B 2 472 ? 61.982  90.115  40.174 1.00 260.32 ? 472 TYR B CZ  1 
ATOM   3565 O OH  . TYR B 2 472 ? 61.025  89.932  39.208 1.00 298.14 ? 472 TYR B OH  1 
ATOM   3566 N N   . PHE B 2 473 ? 65.871  93.657  42.347 1.00 208.62 ? 473 PHE B N   1 
ATOM   3567 C CA  . PHE B 2 473 ? 65.637  94.897  41.623 1.00 202.51 ? 473 PHE B CA  1 
ATOM   3568 C C   . PHE B 2 473 ? 66.853  95.258  40.764 1.00 198.40 ? 473 PHE B C   1 
ATOM   3569 O O   . PHE B 2 473 ? 66.707  95.415  39.553 1.00 231.34 ? 473 PHE B O   1 
ATOM   3570 C CB  . PHE B 2 473 ? 65.234  96.012  42.594 1.00 196.39 ? 473 PHE B CB  1 
ATOM   3571 C CG  . PHE B 2 473 ? 63.920  95.789  43.311 1.00 250.92 ? 473 PHE B CG  1 
ATOM   3572 C CD1 . PHE B 2 473 ? 62.788  95.323  42.634 1.00 269.81 ? 473 PHE B CD1 1 
ATOM   3573 C CD2 . PHE B 2 473 ? 63.812  96.053  44.674 1.00 302.46 ? 473 PHE B CD2 1 
ATOM   3574 C CE1 . PHE B 2 473 ? 61.587  95.121  43.307 1.00 290.60 ? 473 PHE B CE1 1 
ATOM   3575 C CE2 . PHE B 2 473 ? 62.607  95.857  45.341 1.00 341.99 ? 473 PHE B CE2 1 
ATOM   3576 C CZ  . PHE B 2 473 ? 61.498  95.393  44.657 1.00 326.29 ? 473 PHE B CZ  1 
ATOM   3577 N N   . PHE B 2 474 ? 68.037  95.381  41.379 1.00 149.44 ? 474 PHE B N   1 
ATOM   3578 C CA  . PHE B 2 474 ? 69.275  95.724  40.682 1.00 198.62 ? 474 PHE B CA  1 
ATOM   3579 C C   . PHE B 2 474 ? 69.660  94.709  39.586 1.00 184.12 ? 474 PHE B C   1 
ATOM   3580 O O   . PHE B 2 474 ? 70.175  95.096  38.532 1.00 229.86 ? 474 PHE B O   1 
ATOM   3581 C CB  . PHE B 2 474 ? 70.386  95.869  41.728 1.00 217.42 ? 474 PHE B CB  1 
ATOM   3582 C CG  . PHE B 2 474 ? 71.797  96.012  41.201 1.00 227.15 ? 474 PHE B CG  1 
ATOM   3583 C CD1 . PHE B 2 474 ? 72.584  94.898  40.903 1.00 207.86 ? 474 PHE B CD1 1 
ATOM   3584 C CD2 . PHE B 2 474 ? 72.348  97.272  41.003 1.00 257.85 ? 474 PHE B CD2 1 
ATOM   3585 C CE1 . PHE B 2 474 ? 73.877  95.034  40.421 1.00 231.16 ? 474 PHE B CE1 1 
ATOM   3586 C CE2 . PHE B 2 474 ? 73.648  97.415  40.517 1.00 322.82 ? 474 PHE B CE2 1 
ATOM   3587 C CZ  . PHE B 2 474 ? 74.408  96.294  40.232 1.00 310.38 ? 474 PHE B CZ  1 
ATOM   3588 N N   . GLY B 2 475 ? 69.435  93.416  39.820 1.00 144.51 ? 475 GLY B N   1 
ATOM   3589 C CA  . GLY B 2 475 ? 69.927  92.375  38.933 1.00 214.14 ? 475 GLY B CA  1 
ATOM   3590 C C   . GLY B 2 475 ? 68.945  91.892  37.864 1.00 235.16 ? 475 GLY B C   1 
ATOM   3591 O O   . GLY B 2 475 ? 69.383  91.340  36.864 1.00 245.38 ? 475 GLY B O   1 
ATOM   3592 N N   . VAL B 2 476 ? 67.633  92.081  38.048 1.00 216.90 ? 476 VAL B N   1 
ATOM   3593 C CA  . VAL B 2 476 ? 66.609  91.464  37.197 1.00 255.76 ? 476 VAL B CA  1 
ATOM   3594 C C   . VAL B 2 476 ? 65.503  92.449  36.780 1.00 316.79 ? 476 VAL B C   1 
ATOM   3595 O O   . VAL B 2 476 ? 65.230  92.553  35.584 1.00 385.42 ? 476 VAL B O   1 
ATOM   3596 C CB  . VAL B 2 476 ? 66.011  90.205  37.863 1.00 215.15 ? 476 VAL B CB  1 
ATOM   3597 C CG1 . VAL B 2 476 ? 64.898  89.569  37.035 1.00 257.14 ? 476 VAL B CG1 1 
ATOM   3598 C CG2 . VAL B 2 476 ? 67.071  89.156  38.148 1.00 242.68 ? 476 VAL B CG2 1 
ATOM   3599 N N   . TRP B 2 477 ? 64.858  93.153  37.726 1.00 310.59 ? 477 TRP B N   1 
ATOM   3600 C CA  . TRP B 2 477 ? 63.600  93.851  37.446 1.00 301.75 ? 477 TRP B CA  1 
ATOM   3601 C C   . TRP B 2 477 ? 63.780  95.306  36.984 1.00 270.36 ? 477 TRP B C   1 
ATOM   3602 O O   . TRP B 2 477 ? 63.072  95.740  36.070 1.00 259.95 ? 477 TRP B O   1 
ATOM   3603 C CB  . TRP B 2 477 ? 62.696  93.771  38.686 1.00 361.75 ? 477 TRP B CB  1 
ATOM   3604 C CG  . TRP B 2 477 ? 61.350  94.445  38.544 1.00 388.40 ? 477 TRP B CG  1 
ATOM   3605 C CD1 . TRP B 2 477 ? 60.185  93.838  38.167 1.00 401.16 ? 477 TRP B CD1 1 
ATOM   3606 C CD2 . TRP B 2 477 ? 61.019  95.846  38.778 1.00 386.83 ? 477 TRP B CD2 1 
ATOM   3607 N NE1 . TRP B 2 477 ? 59.164  94.756  38.144 1.00 399.43 ? 477 TRP B NE1 1 
ATOM   3608 C CE2 . TRP B 2 477 ? 59.634  95.996  38.513 1.00 407.50 ? 477 TRP B CE2 1 
ATOM   3609 C CE3 . TRP B 2 477 ? 61.746  96.984  39.183 1.00 338.77 ? 477 TRP B CE3 1 
ATOM   3610 C CZ2 . TRP B 2 477 ? 58.980  97.234  38.641 1.00 391.07 ? 477 TRP B CZ2 1 
ATOM   3611 C CZ3 . TRP B 2 477 ? 61.104  98.205  39.305 1.00 319.49 ? 477 TRP B CZ3 1 
ATOM   3612 C CH2 . TRP B 2 477 ? 59.735  98.324  39.038 1.00 367.29 ? 477 TRP B CH2 1 
ATOM   3613 N N   . TRP B 2 478 ? 64.702  96.061  37.605 1.00 293.91 ? 478 TRP B N   1 
ATOM   3614 C CA  . TRP B 2 478 ? 64.931  97.467  37.274 1.00 335.65 ? 478 TRP B CA  1 
ATOM   3615 C C   . TRP B 2 478 ? 65.810  97.615  36.019 1.00 326.14 ? 478 TRP B C   1 
ATOM   3616 O O   . TRP B 2 478 ? 65.686  98.621  35.309 1.00 371.45 ? 478 TRP B O   1 
ATOM   3617 C CB  . TRP B 2 478 ? 65.525  98.173  38.509 1.00 383.51 ? 478 TRP B CB  1 
ATOM   3618 C CG  . TRP B 2 478 ? 65.513  99.688  38.530 1.00 412.49 ? 478 TRP B CG  1 
ATOM   3619 C CD1 . TRP B 2 478 ? 64.899  100.531 37.650 1.00 427.88 ? 478 TRP B CD1 1 
ATOM   3620 C CD2 . TRP B 2 478 ? 66.163  100.553 39.510 1.00 437.53 ? 478 TRP B CD2 1 
ATOM   3621 N NE1 . TRP B 2 478 ? 65.117  101.839 38.004 1.00 425.65 ? 478 TRP B NE1 1 
ATOM   3622 C CE2 . TRP B 2 478 ? 65.888  101.893 39.142 1.00 433.39 ? 478 TRP B CE2 1 
ATOM   3623 C CE3 . TRP B 2 478 ? 66.947  100.333 40.659 1.00 428.68 ? 478 TRP B CE3 1 
ATOM   3624 C CZ2 . TRP B 2 478 ? 66.372  102.988 39.882 1.00 420.02 ? 478 TRP B CZ2 1 
ATOM   3625 C CZ3 . TRP B 2 478 ? 67.424  101.409 41.390 1.00 375.13 ? 478 TRP B CZ3 1 
ATOM   3626 C CH2 . TRP B 2 478 ? 67.137  102.721 41.004 1.00 389.00 ? 478 TRP B CH2 1 
ATOM   3627 N N   . LYS B 2 479 ? 66.688  96.622  35.750 1.00 297.30 ? 479 LYS B N   1 
ATOM   3628 C CA  . LYS B 2 479 ? 67.522  96.527  34.547 1.00 344.99 ? 479 LYS B CA  1 
ATOM   3629 C C   . LYS B 2 479 ? 68.326  97.816  34.322 1.00 386.49 ? 479 LYS B C   1 
ATOM   3630 O O   . LYS B 2 479 ? 68.301  98.389  33.230 1.00 395.96 ? 479 LYS B O   1 
ATOM   3631 C CB  . LYS B 2 479 ? 66.680  96.169  33.310 1.00 358.36 ? 479 LYS B CB  1 
ATOM   3632 C CG  . LYS B 2 479 ? 65.848  94.897  33.413 1.00 382.23 ? 479 LYS B CG  1 
ATOM   3633 C CD  . LYS B 2 479 ? 65.161  94.535  32.114 1.00 386.32 ? 479 LYS B CD  1 
ATOM   3634 C CE  . LYS B 2 479 ? 64.072  93.493  32.273 1.00 406.02 ? 479 LYS B CE  1 
ATOM   3635 N NZ  . LYS B 2 479 ? 64.595  92.208  32.794 1.00 421.43 ? 479 LYS B NZ  1 
ATOM   3636 N N   . ASN B 2 480 ? 69.051  98.250  35.364 1.00 377.20 ? 480 ASN B N   1 
ATOM   3637 C CA  . ASN B 2 480 ? 69.673  99.570  35.418 1.00 377.17 ? 480 ASN B CA  1 
ATOM   3638 C C   . ASN B 2 480 ? 70.506  99.864  34.157 1.00 400.87 ? 480 ASN B C   1 
ATOM   3639 O O   . ASN B 2 480 ? 71.480  99.178  33.852 1.00 365.63 ? 480 ASN B O   1 
ATOM   3640 C CB  . ASN B 2 480 ? 70.469  99.745  36.717 1.00 330.72 ? 480 ASN B CB  1 
ATOM   3641 C CG  . ASN B 2 480 ? 69.567  99.844  37.928 1.00 286.78 ? 480 ASN B CG  1 
ATOM   3642 O OD1 . ASN B 2 480 ? 68.860  98.892  38.242 1.00 300.08 ? 480 ASN B OD1 1 
ATOM   3643 N ND2 . ASN B 2 480 ? 69.573  100.977 38.615 1.00 271.10 ? 480 ASN B ND2 1 
ATOM   3644 N N   . LYS B 2 481 ? 70.098  100.924 33.440 1.00 396.20 ? 481 LYS B N   1 
ATOM   3645 C CA  . LYS B 2 481 ? 70.542  101.248 32.086 1.00 416.92 ? 481 LYS B CA  1 
ATOM   3646 C C   . LYS B 2 481 ? 71.965  101.824 31.943 1.00 422.13 ? 481 LYS B C   1 
ATOM   3647 O O   . LYS B 2 481 ? 72.505  101.694 30.840 1.00 437.94 ? 481 LYS B O   1 
ATOM   3648 C CB  . LYS B 2 481 ? 69.548  102.257 31.493 1.00 431.82 ? 481 LYS B CB  1 
ATOM   3649 C CG  . LYS B 2 481 ? 68.104  101.780 31.344 1.00 408.25 ? 481 LYS B CG  1 
ATOM   3650 C CD  . LYS B 2 481 ? 67.900  100.669 30.332 1.00 439.04 ? 481 LYS B CD  1 
ATOM   3651 C CE  . LYS B 2 481 ? 68.233  101.059 28.906 1.00 502.25 ? 481 LYS B CE  1 
ATOM   3652 N NZ  . LYS B 2 481 ? 67.900  99.980  27.947 1.00 526.83 ? 481 LYS B NZ  1 
ATOM   3653 N N   . PRO B 2 482 ? 72.618  102.496 32.940 1.00 379.66 ? 482 PRO B N   1 
ATOM   3654 C CA  . PRO B 2 482 ? 73.922  103.144 32.724 1.00 337.10 ? 482 PRO B CA  1 
ATOM   3655 C C   . PRO B 2 482 ? 75.022  102.284 32.086 1.00 311.36 ? 482 PRO B C   1 
ATOM   3656 O O   . PRO B 2 482 ? 75.309  101.167 32.527 1.00 302.39 ? 482 PRO B O   1 
ATOM   3657 C CB  . PRO B 2 482 ? 74.353  103.590 34.138 1.00 308.32 ? 482 PRO B CB  1 
ATOM   3658 C CG  . PRO B 2 482 ? 73.051  103.839 34.845 1.00 331.59 ? 482 PRO B CG  1 
ATOM   3659 C CD  . PRO B 2 482 ? 72.147  102.745 34.313 1.00 366.50 ? 482 PRO B CD  1 
ATOM   3660 N N   . LYS B 2 483 ? 75.642  102.834 31.032 1.00 323.41 ? 483 LYS B N   1 
ATOM   3661 C CA  . LYS B 2 483 ? 76.632  102.118 30.232 1.00 353.22 ? 483 LYS B CA  1 
ATOM   3662 C C   . LYS B 2 483 ? 77.911  101.855 31.040 1.00 339.42 ? 483 LYS B C   1 
ATOM   3663 O O   . LYS B 2 483 ? 78.525  100.805 30.858 1.00 362.70 ? 483 LYS B O   1 
ATOM   3664 C CB  . LYS B 2 483 ? 76.897  102.881 28.925 1.00 399.19 ? 483 LYS B CB  1 
ATOM   3665 C CG  . LYS B 2 483 ? 77.636  102.103 27.839 1.00 453.30 ? 483 LYS B CG  1 
ATOM   3666 C CD  . LYS B 2 483 ? 76.968  100.790 27.449 1.00 523.66 ? 483 LYS B CD  1 
ATOM   3667 C CE  . LYS B 2 483 ? 77.321  100.281 26.063 1.00 573.22 ? 483 LYS B CE  1 
ATOM   3668 N NZ  . LYS B 2 483 ? 78.754  99.933  25.921 1.00 593.06 ? 483 LYS B NZ  1 
ATOM   3669 N N   . TRP B 2 484 ? 78.307  102.774 31.939 1.00 329.00 ? 484 TRP B N   1 
ATOM   3670 C CA  . TRP B 2 484 ? 79.430  102.555 32.852 1.00 348.10 ? 484 TRP B CA  1 
ATOM   3671 C C   . TRP B 2 484 ? 79.183  101.362 33.790 1.00 354.80 ? 484 TRP B C   1 
ATOM   3672 O O   . TRP B 2 484 ? 80.120  100.609 34.075 1.00 321.87 ? 484 TRP B O   1 
ATOM   3673 C CB  . TRP B 2 484 ? 79.768  103.836 33.646 1.00 366.18 ? 484 TRP B CB  1 
ATOM   3674 C CG  . TRP B 2 484 ? 78.645  104.418 34.477 1.00 380.60 ? 484 TRP B CG  1 
ATOM   3675 C CD1 . TRP B 2 484 ? 77.870  105.479 34.111 1.00 391.89 ? 484 TRP B CD1 1 
ATOM   3676 C CD2 . TRP B 2 484 ? 78.162  104.008 35.790 1.00 382.38 ? 484 TRP B CD2 1 
ATOM   3677 N NE1 . TRP B 2 484 ? 76.944  105.755 35.083 1.00 373.88 ? 484 TRP B NE1 1 
ATOM   3678 C CE2 . TRP B 2 484 ? 77.091  104.875 36.128 1.00 360.26 ? 484 TRP B CE2 1 
ATOM   3679 C CE3 . TRP B 2 484 ? 78.512  103.005 36.714 1.00 403.02 ? 484 TRP B CE3 1 
ATOM   3680 C CZ2 . TRP B 2 484 ? 76.386  104.761 37.337 1.00 348.03 ? 484 TRP B CZ2 1 
ATOM   3681 C CZ3 . TRP B 2 484 ? 77.813  102.883 37.901 1.00 411.89 ? 484 TRP B CZ3 1 
ATOM   3682 C CH2 . TRP B 2 484 ? 76.766  103.759 38.210 1.00 381.02 ? 484 TRP B CH2 1 
ATOM   3683 N N   . LEU B 2 485 ? 77.933  101.176 34.255 1.00 353.66 ? 485 LEU B N   1 
ATOM   3684 C CA  . LEU B 2 485 ? 77.565  100.060 35.123 1.00 313.28 ? 485 LEU B CA  1 
ATOM   3685 C C   . LEU B 2 485 ? 77.675  98.753  34.340 1.00 261.67 ? 485 LEU B C   1 
ATOM   3686 O O   . LEU B 2 485 ? 78.306  97.811  34.817 1.00 259.63 ? 485 LEU B O   1 
ATOM   3687 C CB  . LEU B 2 485 ? 76.155  100.290 35.690 1.00 327.12 ? 485 LEU B CB  1 
ATOM   3688 C CG  . LEU B 2 485 ? 75.630  99.227  36.657 1.00 326.80 ? 485 LEU B CG  1 
ATOM   3689 C CD1 . LEU B 2 485 ? 76.424  99.220  37.955 1.00 344.41 ? 485 LEU B CD1 1 
ATOM   3690 C CD2 . LEU B 2 485 ? 74.158  99.446  36.955 1.00 317.46 ? 485 LEU B CD2 1 
ATOM   3691 N N   . LEU B 2 486 ? 77.086  98.703  33.136 1.00 247.18 ? 486 LEU B N   1 
ATOM   3692 C CA  . LEU B 2 486 ? 77.144  97.520  32.286 1.00 282.98 ? 486 LEU B CA  1 
ATOM   3693 C C   . LEU B 2 486 ? 78.593  97.150  31.911 1.00 248.71 ? 486 LEU B C   1 
ATOM   3694 O O   . LEU B 2 486 ? 78.942  95.969  31.956 1.00 250.11 ? 486 LEU B O   1 
ATOM   3695 C CB  . LEU B 2 486 ? 76.248  97.747  31.060 1.00 330.81 ? 486 LEU B CB  1 
ATOM   3696 C CG  . LEU B 2 486 ? 76.179  96.597  30.055 1.00 382.69 ? 486 LEU B CG  1 
ATOM   3697 C CD1 . LEU B 2 486 ? 75.672  95.314  30.698 1.00 393.45 ? 486 LEU B CD1 1 
ATOM   3698 C CD2 . LEU B 2 486 ? 75.288  96.971  28.884 1.00 407.19 ? 486 LEU B CD2 1 
ATOM   3699 N N   . GLN B 2 487 ? 79.451  98.121  31.560 1.00 289.08 ? 487 GLN B N   1 
ATOM   3700 C CA  . GLN B 2 487 ? 80.869  97.853  31.310 1.00 318.14 ? 487 GLN B CA  1 
ATOM   3701 C C   . GLN B 2 487 ? 81.615  97.391  32.572 1.00 285.55 ? 487 GLN B C   1 
ATOM   3702 O O   . GLN B 2 487 ? 82.543  96.589  32.450 1.00 289.59 ? 487 GLN B O   1 
ATOM   3703 C CB  . GLN B 2 487 ? 81.572  99.073  30.694 1.00 359.53 ? 487 GLN B CB  1 
ATOM   3704 C CG  . GLN B 2 487 ? 81.140  99.422  29.271 1.00 378.60 ? 487 GLN B CG  1 
ATOM   3705 C CD  . GLN B 2 487 ? 81.186  98.287  28.271 1.00 401.80 ? 487 GLN B CD  1 
ATOM   3706 O OE1 . GLN B 2 487 ? 80.236  98.068  27.518 1.00 438.69 ? 487 GLN B OE1 1 
ATOM   3707 N NE2 . GLN B 2 487 ? 82.293  97.560  28.246 1.00 380.84 ? 487 GLN B NE2 1 
ATOM   3708 N N   . GLY B 2 488 ? 81.226  97.869  33.766 1.00 275.79 ? 488 GLY B N   1 
ATOM   3709 C CA  . GLY B 2 488 ? 81.765  97.374  35.029 1.00 309.19 ? 488 GLY B CA  1 
ATOM   3710 C C   . GLY B 2 488 ? 81.389  95.914  35.305 1.00 301.81 ? 488 GLY B C   1 
ATOM   3711 O O   . GLY B 2 488 ? 82.247  95.111  35.675 1.00 276.24 ? 488 GLY B O   1 
ATOM   3712 N N   . ILE B 2 489 ? 80.107  95.572  35.111 1.00 273.29 ? 489 ILE B N   1 
ATOM   3713 C CA  . ILE B 2 489 ? 79.590  94.208  35.200 1.00 231.95 ? 489 ILE B CA  1 
ATOM   3714 C C   . ILE B 2 489 ? 80.339  93.305  34.215 1.00 196.51 ? 489 ILE B C   1 
ATOM   3715 O O   . ILE B 2 489 ? 80.794  92.226  34.598 1.00 174.16 ? 489 ILE B O   1 
ATOM   3716 C CB  . ILE B 2 489 ? 78.052  94.209  34.989 1.00 237.93 ? 489 ILE B CB  1 
ATOM   3717 C CG1 . ILE B 2 489 ? 77.345  94.849  36.187 1.00 272.29 ? 489 ILE B CG1 1 
ATOM   3718 C CG2 . ILE B 2 489 ? 77.482  92.818  34.693 1.00 232.98 ? 489 ILE B CG2 1 
ATOM   3719 C CD1 . ILE B 2 489 ? 75.909  95.267  35.927 1.00 318.71 ? 489 ILE B CD1 1 
ATOM   3720 N N   . PHE B 2 490 ? 80.473  93.741  32.955 1.00 230.23 ? 490 PHE B N   1 
ATOM   3721 C CA  . PHE B 2 490 ? 81.196  92.994  31.935 1.00 268.45 ? 490 PHE B CA  1 
ATOM   3722 C C   . PHE B 2 490 ? 82.663  92.785  32.343 1.00 200.19 ? 490 PHE B C   1 
ATOM   3723 O O   . PHE B 2 490 ? 83.170  91.667  32.268 1.00 201.23 ? 490 PHE B O   1 
ATOM   3724 C CB  . PHE B 2 490 ? 81.044  93.669  30.564 1.00 282.04 ? 490 PHE B CB  1 
ATOM   3725 C CG  . PHE B 2 490 ? 81.600  92.829  29.438 1.00 302.42 ? 490 PHE B CG  1 
ATOM   3726 C CD1 . PHE B 2 490 ? 82.935  92.943  29.069 1.00 313.54 ? 490 PHE B CD1 1 
ATOM   3727 C CD2 . PHE B 2 490 ? 80.803  91.901  28.768 1.00 311.14 ? 490 PHE B CD2 1 
ATOM   3728 C CE1 . PHE B 2 490 ? 83.455  92.162  28.039 1.00 328.71 ? 490 PHE B CE1 1 
ATOM   3729 C CE2 . PHE B 2 490 ? 81.327  91.119  27.744 1.00 317.40 ? 490 PHE B CE2 1 
ATOM   3730 C CZ  . PHE B 2 490 ? 82.651  91.252  27.379 1.00 314.38 ? 490 PHE B CZ  1 
ATOM   3731 N N   . SER B 2 491 ? 83.345  93.847  32.785 1.00 212.75 ? 491 SER B N   1 
ATOM   3732 C CA  . SER B 2 491 ? 84.738  93.771  33.221 1.00 266.59 ? 491 SER B CA  1 
ATOM   3733 C C   . SER B 2 491 ? 84.918  92.776  34.375 1.00 269.08 ? 491 SER B C   1 
ATOM   3734 O O   . SER B 2 491 ? 85.854  91.974  34.360 1.00 225.40 ? 491 SER B O   1 
ATOM   3735 C CB  . SER B 2 491 ? 85.270  95.140  33.599 1.00 318.24 ? 491 SER B CB  1 
ATOM   3736 O OG  . SER B 2 491 ? 85.200  96.041  32.504 1.00 316.68 ? 491 SER B OG  1 
ATOM   3737 N N   . THR B 2 492 ? 84.022  92.823  35.374 1.00 260.35 ? 492 THR B N   1 
ATOM   3738 C CA  . THR B 2 492 ? 84.003  91.881  36.488 1.00 256.28 ? 492 THR B CA  1 
ATOM   3739 C C   . THR B 2 492 ? 83.826  90.446  35.987 1.00 190.04 ? 492 THR B C   1 
ATOM   3740 O O   . THR B 2 492 ? 84.501  89.527  36.452 1.00 201.39 ? 492 THR B O   1 
ATOM   3741 C CB  . THR B 2 492 ? 82.899  92.237  37.499 1.00 326.09 ? 492 THR B CB  1 
ATOM   3742 O OG1 . THR B 2 492 ? 83.083  93.578  37.952 1.00 298.01 ? 492 THR B OG1 1 
ATOM   3743 C CG2 . THR B 2 492 ? 82.883  91.340  38.720 1.00 426.23 ? 492 THR B CG2 1 
ATOM   3744 N N   . THR B 2 493 ? 82.908  90.248  35.039 1.00 173.21 ? 493 THR B N   1 
ATOM   3745 C CA  . THR B 2 493 ? 82.653  88.943  34.439 1.00 182.75 ? 493 THR B CA  1 
ATOM   3746 C C   . THR B 2 493 ? 83.888  88.409  33.707 1.00 177.25 ? 493 THR B C   1 
ATOM   3747 O O   . THR B 2 493 ? 84.314  87.298  33.999 1.00 146.51 ? 493 THR B O   1 
ATOM   3748 C CB  . THR B 2 493 ? 81.436  88.990  33.504 1.00 233.93 ? 493 THR B CB  1 
ATOM   3749 O OG1 . THR B 2 493 ? 80.296  89.399  34.260 1.00 173.63 ? 493 THR B OG1 1 
ATOM   3750 C CG2 . THR B 2 493 ? 81.121  87.660  32.852 1.00 243.43 ? 493 THR B CG2 1 
ATOM   3751 N N   . VAL B 2 494 ? 84.480  89.172  32.773 1.00 229.35 ? 494 VAL B N   1 
ATOM   3752 C CA  . VAL B 2 494 ? 85.616  88.666  32.001 1.00 246.10 ? 494 VAL B CA  1 
ATOM   3753 C C   . VAL B 2 494 ? 86.842  88.453  32.891 1.00 212.81 ? 494 VAL B C   1 
ATOM   3754 O O   . VAL B 2 494 ? 87.624  87.552  32.604 1.00 148.42 ? 494 VAL B O   1 
ATOM   3755 C CB  . VAL B 2 494 ? 85.968  89.516  30.759 1.00 289.45 ? 494 VAL B CB  1 
ATOM   3756 C CG1 . VAL B 2 494 ? 84.784  89.591  29.815 1.00 319.14 ? 494 VAL B CG1 1 
ATOM   3757 C CG2 . VAL B 2 494 ? 86.480  90.915  31.070 1.00 285.28 ? 494 VAL B CG2 1 
ATOM   3758 N N   . LEU B 2 495 ? 87.016  89.242  33.959 1.00 201.03 ? 495 LEU B N   1 
ATOM   3759 C CA  . LEU B 2 495 ? 88.045  88.970  34.951 1.00 229.39 ? 495 LEU B CA  1 
ATOM   3760 C C   . LEU B 2 495 ? 87.888  87.542  35.476 1.00 231.38 ? 495 LEU B C   1 
ATOM   3761 O O   . LEU B 2 495 ? 88.852  86.784  35.441 1.00 180.83 ? 495 LEU B O   1 
ATOM   3762 C CB  . LEU B 2 495 ? 87.967  90.028  36.062 1.00 267.45 ? 495 LEU B CB  1 
ATOM   3763 C CG  . LEU B 2 495 ? 88.834  89.789  37.296 1.00 353.75 ? 495 LEU B CG  1 
ATOM   3764 C CD1 . LEU B 2 495 ? 90.309  89.740  36.932 1.00 378.61 ? 495 LEU B CD1 1 
ATOM   3765 C CD2 . LEU B 2 495 ? 88.580  90.876  38.328 1.00 364.13 ? 495 LEU B CD2 1 
ATOM   3766 N N   . CYS B 2 496 ? 86.688  87.171  35.948 1.00 257.24 ? 496 CYS B N   1 
ATOM   3767 C CA  . CYS B 2 496 ? 86.425  85.822  36.442 1.00 231.70 ? 496 CYS B CA  1 
ATOM   3768 C C   . CYS B 2 496 ? 86.642  84.780  35.346 1.00 179.40 ? 496 CYS B C   1 
ATOM   3769 O O   . CYS B 2 496 ? 87.249  83.740  35.614 1.00 161.60 ? 496 CYS B O   1 
ATOM   3770 C CB  . CYS B 2 496 ? 85.020  85.732  37.024 1.00 237.76 ? 496 CYS B CB  1 
ATOM   3771 S SG  . CYS B 2 496 ? 84.775  86.864  38.412 1.00 349.87 ? 496 CYS B SG  1 
ATOM   3772 N N   . GLN B 2 497 ? 86.179  85.049  34.113 1.00 169.30 ? 497 GLN B N   1 
ATOM   3773 C CA  . GLN B 2 497 ? 86.369  84.123  33.007 1.00 182.59 ? 497 GLN B CA  1 
ATOM   3774 C C   . GLN B 2 497 ? 87.853  83.849  32.770 1.00 200.02 ? 497 GLN B C   1 
ATOM   3775 O O   . GLN B 2 497 ? 88.227  82.690  32.620 1.00 145.58 ? 497 GLN B O   1 
ATOM   3776 C CB  . GLN B 2 497 ? 85.718  84.635  31.727 1.00 178.94 ? 497 GLN B CB  1 
ATOM   3777 C CG  . GLN B 2 497 ? 84.205  84.645  31.765 1.00 185.79 ? 497 GLN B CG  1 
ATOM   3778 C CD  . GLN B 2 497 ? 83.614  84.762  30.382 1.00 259.13 ? 497 GLN B CD  1 
ATOM   3779 O OE1 . GLN B 2 497 ? 83.155  85.826  29.979 1.00 327.27 ? 497 GLN B OE1 1 
ATOM   3780 N NE2 . GLN B 2 497 ? 83.628  83.676  29.623 1.00 261.41 ? 497 GLN B NE2 1 
ATOM   3781 N N   . LYS B 2 498 ? 88.689  84.897  32.741 1.00 199.59 ? 498 LYS B N   1 
ATOM   3782 C CA  . LYS B 2 498 ? 90.128  84.773  32.520 1.00 253.88 ? 498 LYS B CA  1 
ATOM   3783 C C   . LYS B 2 498 ? 90.824  84.107  33.710 1.00 227.00 ? 498 LYS B C   1 
ATOM   3784 O O   . LYS B 2 498 ? 91.743  83.308  33.512 1.00 211.30 ? 498 LYS B O   1 
ATOM   3785 C CB  . LYS B 2 498 ? 90.726  86.151  32.214 1.00 259.20 ? 498 LYS B CB  1 
ATOM   3786 C CG  . LYS B 2 498 ? 90.318  86.722  30.860 1.00 272.90 ? 498 LYS B CG  1 
ATOM   3787 C CD  . LYS B 2 498 ? 90.866  88.100  30.547 1.00 290.66 ? 498 LYS B CD  1 
ATOM   3788 C CE  . LYS B 2 498 ? 90.352  89.204  31.450 1.00 312.11 ? 498 LYS B CE  1 
ATOM   3789 N NZ  . LYS B 2 498 ? 90.895  90.535  31.076 1.00 269.19 ? 498 LYS B NZ  1 
ATOM   3790 N N   . LEU B 2 499 ? 90.380  84.421  34.936 1.00 213.37 ? 499 LEU B N   1 
ATOM   3791 C CA  . LEU B 2 499 ? 90.997  83.929  36.167 1.00 218.98 ? 499 LEU B CA  1 
ATOM   3792 C C   . LEU B 2 499 ? 90.590  82.491  36.520 1.00 187.04 ? 499 LEU B C   1 
ATOM   3793 O O   . LEU B 2 499 ? 91.290  81.862  37.315 1.00 174.59 ? 499 LEU B O   1 
ATOM   3794 C CB  . LEU B 2 499 ? 90.640  84.916  37.290 1.00 222.66 ? 499 LEU B CB  1 
ATOM   3795 C CG  . LEU B 2 499 ? 91.374  84.772  38.614 1.00 244.62 ? 499 LEU B CG  1 
ATOM   3796 C CD1 . LEU B 2 499 ? 92.893  84.765  38.422 1.00 273.31 ? 499 LEU B CD1 1 
ATOM   3797 C CD2 . LEU B 2 499 ? 90.943  85.910  39.539 1.00 248.26 ? 499 LEU B CD2 1 
ATOM   3798 N N   . MET B 2 500 ? 89.493  81.951  35.950 1.00 187.41 ? 500 MET B N   1 
ATOM   3799 C CA  . MET B 2 500 ? 89.129  80.541  36.101 1.00 216.54 ? 500 MET B CA  1 
ATOM   3800 C C   . MET B 2 500 ? 89.227  79.737  34.787 1.00 207.70 ? 500 MET B C   1 
ATOM   3801 O O   . MET B 2 500 ? 89.102  78.510  34.831 1.00 221.55 ? 500 MET B O   1 
ATOM   3802 C CB  . MET B 2 500 ? 87.703  80.452  36.668 1.00 262.50 ? 500 MET B CB  1 
ATOM   3803 C CG  . MET B 2 500 ? 87.553  81.121  38.032 1.00 270.23 ? 500 MET B CG  1 
ATOM   3804 S SD  . MET B 2 500 ? 85.919  80.977  38.770 1.00 194.36 ? 500 MET B SD  1 
ATOM   3805 C CE  . MET B 2 500 ? 85.929  82.376  39.894 1.00 251.50 ? 500 MET B CE  1 
ATOM   3806 N N   . GLN B 2 501 ? 89.445  80.394  33.630 1.00 203.66 ? 501 GLN B N   1 
ATOM   3807 C CA  . GLN B 2 501 ? 89.404  79.801  32.290 1.00 229.69 ? 501 GLN B CA  1 
ATOM   3808 C C   . GLN B 2 501 ? 88.054  79.101  32.066 1.00 229.75 ? 501 GLN B C   1 
ATOM   3809 O O   . GLN B 2 501 ? 87.985  77.878  31.996 1.00 204.01 ? 501 GLN B O   1 
ATOM   3810 C CB  . GLN B 2 501 ? 90.640  78.908  32.076 1.00 256.44 ? 501 GLN B CB  1 
ATOM   3811 C CG  . GLN B 2 501 ? 90.772  78.305  30.673 1.00 292.64 ? 501 GLN B CG  1 
ATOM   3812 C CD  . GLN B 2 501 ? 92.116  77.661  30.412 1.00 313.13 ? 501 GLN B CD  1 
ATOM   3813 O OE1 . GLN B 2 501 ? 93.157  78.301  30.543 1.00 347.74 ? 501 GLN B OE1 1 
ATOM   3814 N NE2 . GLN B 2 501 ? 92.119  76.391  30.038 1.00 325.33 ? 501 GLN B NE2 1 
ATOM   3815 N N   . VAL B 2 502 ? 86.961  79.887  31.968 1.00 198.82 ? 502 VAL B N   1 
ATOM   3816 C CA  . VAL B 2 502 ? 85.615  79.337  31.786 1.00 205.85 ? 502 VAL B CA  1 
ATOM   3817 C C   . VAL B 2 502 ? 84.813  80.047  30.692 1.00 226.93 ? 502 VAL B C   1 
ATOM   3818 O O   . VAL B 2 502 ? 84.978  81.240  30.436 1.00 207.44 ? 502 VAL B O   1 
ATOM   3819 C CB  . VAL B 2 502 ? 84.808  79.329  33.096 1.00 167.99 ? 502 VAL B CB  1 
ATOM   3820 C CG1 . VAL B 2 502 ? 85.510  78.467  34.126 1.00 236.98 ? 502 VAL B CG1 1 
ATOM   3821 C CG2 . VAL B 2 502 ? 84.555  80.717  33.657 1.00 173.74 ? 502 VAL B CG2 1 
ATOM   3822 N N   . VAL B 2 503 ? 83.909  79.267  30.068 1.00 228.24 ? 503 VAL B N   1 
ATOM   3823 C CA  . VAL B 2 503 ? 83.196  79.620  28.847 1.00 162.73 ? 503 VAL B CA  1 
ATOM   3824 C C   . VAL B 2 503 ? 81.724  79.225  28.979 1.00 170.21 ? 503 VAL B C   1 
ATOM   3825 O O   . VAL B 2 503 ? 81.385  78.317  29.757 1.00 258.61 ? 503 VAL B O   1 
ATOM   3826 C CB  . VAL B 2 503 ? 83.828  78.910  27.637 1.00 213.09 ? 503 VAL B CB  1 
ATOM   3827 C CG1 . VAL B 2 503 ? 85.324  79.191  27.548 1.00 270.10 ? 503 VAL B CG1 1 
ATOM   3828 C CG2 . VAL B 2 503 ? 83.575  77.401  27.613 1.00 190.93 ? 503 VAL B CG2 1 
ATOM   3829 N N   . PRO B 2 504 ? 80.797  79.886  28.252 1.00 173.87 ? 504 PRO B N   1 
ATOM   3830 C CA  . PRO B 2 504 ? 79.392  79.450  28.189 1.00 212.02 ? 504 PRO B CA  1 
ATOM   3831 C C   . PRO B 2 504 ? 79.163  78.015  27.701 1.00 192.59 ? 504 PRO B C   1 
ATOM   3832 O O   . PRO B 2 504 ? 79.945  77.469  26.936 1.00 173.78 ? 504 PRO B O   1 
ATOM   3833 C CB  . PRO B 2 504 ? 78.741  80.446  27.211 1.00 254.67 ? 504 PRO B CB  1 
ATOM   3834 C CG  . PRO B 2 504 ? 79.646  81.674  27.273 1.00 252.28 ? 504 PRO B CG  1 
ATOM   3835 C CD  . PRO B 2 504 ? 81.040  81.122  27.504 1.00 191.23 ? 504 PRO B CD  1 
ATOM   3836 N N   . GLN B 2 505 ? 78.070  77.413  28.178 1.00 254.76 ? 505 GLN B N   1 
ATOM   3837 C CA  . GLN B 2 505 ? 77.567  76.130  27.691 1.00 322.83 ? 505 GLN B CA  1 
ATOM   3838 C C   . GLN B 2 505 ? 76.872  76.317  26.333 1.00 367.88 ? 505 GLN B C   1 
ATOM   3839 O O   . GLN B 2 505 ? 76.445  77.422  25.988 1.00 366.66 ? 505 GLN B O   1 
ATOM   3840 C CB  . GLN B 2 505 ? 76.641  75.494  28.747 1.00 384.61 ? 505 GLN B CB  1 
ATOM   3841 C CG  . GLN B 2 505 ? 75.159  75.911  28.726 1.00 472.00 ? 505 GLN B CG  1 
ATOM   3842 C CD  . GLN B 2 505 ? 74.856  77.388  28.878 1.00 523.48 ? 505 GLN B CD  1 
ATOM   3843 O OE1 . GLN B 2 505 ? 75.671  78.167  29.373 1.00 543.00 ? 505 GLN B OE1 1 
ATOM   3844 N NE2 . GLN B 2 505 ? 73.663  77.793  28.460 1.00 541.58 ? 505 GLN B NE2 1 
ATOM   3845 N N   . GLU B 2 506 ? 76.729  75.221  25.559 1.00 405.05 ? 506 GLU B N   1 
ATOM   3846 C CA  . GLU B 2 506 ? 76.001  75.254  24.290 1.00 435.01 ? 506 GLU B CA  1 
ATOM   3847 C C   . GLU B 2 506 ? 74.510  75.560  24.515 1.00 480.14 ? 506 GLU B C   1 
ATOM   3848 O O   . GLU B 2 506 ? 73.798  74.765  25.130 1.00 520.38 ? 506 GLU B O   1 
ATOM   3849 C CB  . GLU B 2 506 ? 76.156  73.934  23.529 1.00 444.74 ? 506 GLU B CB  1 
ATOM   3850 C CG  . GLU B 2 506 ? 77.593  73.618  23.119 1.00 469.89 ? 506 GLU B CG  1 
ATOM   3851 C CD  . GLU B 2 506 ? 78.387  72.723  24.059 1.00 490.35 ? 506 GLU B CD  1 
ATOM   3852 O OE1 . GLU B 2 506 ? 78.189  72.817  25.282 1.00 476.77 ? 506 GLU B OE1 1 
ATOM   3853 O OE2 . GLU B 2 506 ? 79.216  71.930  23.558 1.00 511.56 ? 506 GLU B OE2 1 
ATOM   3854 N N   . THR B 2 507 ? 74.036  76.715  24.004 1.00 487.73 ? 507 THR B N   1 
ATOM   3855 C CA  . THR B 2 507 ? 72.653  77.162  24.185 1.00 484.74 ? 507 THR B CA  1 
ATOM   3856 C C   . THR B 2 507 ? 71.687  76.253  23.403 1.00 449.20 ? 507 THR B C   1 
ATOM   3857 O O   . THR B 2 507 ? 71.814  76.148  22.154 1.00 444.26 ? 507 THR B O   1 
ATOM   3858 C CB  . THR B 2 507 ? 72.479  78.647  23.811 1.00 508.00 ? 507 THR B CB  1 
ATOM   3859 O OG1 . THR B 2 507 ? 73.319  79.439  24.650 1.00 529.39 ? 507 THR B OG1 1 
ATOM   3860 C CG2 . THR B 2 507 ? 71.063  79.165  23.970 1.00 516.46 ? 507 THR B CG2 1 
HETATM 3861 C C1  . CLR C 3 .   ? 96.906  62.365  66.687 1.00 253.37 ? 701 CLR A C1  1 
HETATM 3862 C C2  . CLR C 3 .   ? 97.798  61.781  67.789 1.00 308.63 ? 701 CLR A C2  1 
HETATM 3863 C C3  . CLR C 3 .   ? 97.395  60.369  68.144 1.00 328.15 ? 701 CLR A C3  1 
HETATM 3864 C C4  . CLR C 3 .   ? 97.451  59.495  66.906 1.00 347.55 ? 701 CLR A C4  1 
HETATM 3865 C C5  . CLR C 3 .   ? 96.642  60.066  65.752 1.00 308.86 ? 701 CLR A C5  1 
HETATM 3866 C C6  . CLR C 3 .   ? 95.763  59.300  65.122 1.00 288.57 ? 701 CLR A C6  1 
HETATM 3867 C C7  . CLR C 3 .   ? 94.962  59.692  63.918 1.00 286.33 ? 701 CLR A C7  1 
HETATM 3868 C C8  . CLR C 3 .   ? 95.297  61.075  63.352 1.00 249.68 ? 701 CLR A C8  1 
HETATM 3869 C C9  . CLR C 3 .   ? 95.739  62.061  64.462 1.00 209.79 ? 701 CLR A C9  1 
HETATM 3870 C C10 . CLR C 3 .   ? 96.891  61.534  65.376 1.00 274.25 ? 701 CLR A C10 1 
HETATM 3871 C C11 . CLR C 3 .   ? 95.983  63.464  63.862 1.00 205.41 ? 701 CLR A C11 1 
HETATM 3872 C C12 . CLR C 3 .   ? 94.772  63.991  63.081 1.00 162.04 ? 701 CLR A C12 1 
HETATM 3873 C C13 . CLR C 3 .   ? 94.308  63.042  61.967 1.00 182.52 ? 701 CLR A C13 1 
HETATM 3874 C C14 . CLR C 3 .   ? 94.077  61.667  62.640 1.00 226.82 ? 701 CLR A C14 1 
HETATM 3875 C C15 . CLR C 3 .   ? 93.322  60.834  61.603 1.00 193.40 ? 701 CLR A C15 1 
HETATM 3876 C C16 . CLR C 3 .   ? 92.449  61.876  60.884 1.00 205.38 ? 701 CLR A C16 1 
HETATM 3877 C C17 . CLR C 3 .   ? 92.879  63.292  61.380 1.00 184.38 ? 701 CLR A C17 1 
HETATM 3878 C C18 . CLR C 3 .   ? 95.358  62.991  60.835 1.00 210.06 ? 701 CLR A C18 1 
HETATM 3879 C C19 . CLR C 3 .   ? 98.263  61.637  64.669 1.00 322.53 ? 701 CLR A C19 1 
HETATM 3880 C C20 . CLR C 3 .   ? 92.684  64.435  60.348 1.00 189.69 ? 701 CLR A C20 1 
HETATM 3881 C C21 . CLR C 3 .   ? 92.752  65.810  61.018 1.00 149.55 ? 701 CLR A C21 1 
HETATM 3882 C C22 . CLR C 3 .   ? 91.392  64.346  59.508 1.00 171.08 ? 701 CLR A C22 1 
HETATM 3883 C C23 . CLR C 3 .   ? 91.567  64.540  58.018 1.00 147.33 ? 701 CLR A C23 1 
HETATM 3884 C C24 . CLR C 3 .   ? 90.256  64.423  57.249 1.00 205.77 ? 701 CLR A C24 1 
HETATM 3885 C C25 . CLR C 3 .   ? 90.250  64.860  55.747 1.00 214.03 ? 701 CLR A C25 1 
HETATM 3886 C C26 . CLR C 3 .   ? 91.031  66.132  55.514 1.00 177.38 ? 701 CLR A C26 1 
HETATM 3887 C C27 . CLR C 3 .   ? 88.847  65.032  55.154 1.00 134.46 ? 701 CLR A C27 1 
HETATM 3888 O O1  . CLR C 3 .   ? 98.266  59.837  69.155 1.00 289.74 ? 701 CLR A O1  1 
HETATM 3889 C C1  . LBN D 4 .   ? 92.603  77.239  37.577 1.00 335.50 ? 702 LBN A C1  1 
HETATM 3890 N N1  . LBN D 4 .   ? 94.411  71.184  35.608 1.00 407.12 ? 702 LBN A N1  1 
HETATM 3891 P P1  . LBN D 4 .   ? 93.611  76.311  35.320 1.00 302.35 ? 702 LBN A P1  1 
HETATM 3892 C C2  . LBN D 4 .   ? 91.687  76.888  38.726 1.00 278.83 ? 702 LBN A C2  1 
HETATM 3893 C C3  . LBN D 4 .   ? 91.780  75.443  39.158 1.00 304.15 ? 702 LBN A C3  1 
HETATM 3894 C C4  . LBN D 4 .   ? 88.231  79.287  48.448 1.00 199.50 ? 702 LBN A C4  1 
HETATM 3895 C C6  . LBN D 4 .   ? 94.125  72.472  34.852 1.00 380.97 ? 702 LBN A C6  1 
HETATM 3896 O O1  . LBN D 4 .   ? 92.534  76.248  36.515 1.00 305.24 ? 702 LBN A O1  1 
HETATM 3897 C C9  . LBN D 4 .   ? 93.733  73.699  35.643 1.00 354.34 ? 702 LBN A C9  1 
HETATM 3898 O O2  . LBN D 4 .   ? 93.576  74.819  34.730 1.00 337.61 ? 702 LBN A O2  1 
HETATM 3899 C C12 . LBN D 4 .   ? 95.562  71.354  36.545 1.00 413.60 ? 702 LBN A C12 1 
HETATM 3900 O O3  . LBN D 4 .   ? 95.030  76.497  35.781 1.00 286.98 ? 702 LBN A O3  1 
HETATM 3901 C C15 . LBN D 4 .   ? 94.754  70.120  34.618 1.00 381.52 ? 702 LBN A C15 1 
HETATM 3902 O O4  . LBN D 4 .   ? 93.040  77.283  34.336 1.00 242.88 ? 702 LBN A O4  1 
HETATM 3903 C C18 . LBN D 4 .   ? 93.214  70.741  36.380 1.00 444.19 ? 702 LBN A C18 1 
HETATM 3904 C C25 . LBN D 4 .   ? 90.913  74.096  40.903 1.00 320.27 ? 702 LBN A C25 1 
HETATM 3905 O O5  . LBN D 4 .   ? 91.177  75.320  40.467 1.00 325.20 ? 702 LBN A O5  1 
HETATM 3906 C C26 . LBN D 4 .   ? 91.095  74.001  42.391 1.00 309.18 ? 702 LBN A C26 1 
HETATM 3907 O O6  . LBN D 4 .   ? 90.584  73.194  40.178 1.00 257.39 ? 702 LBN A O6  1 
HETATM 3908 C C27 . LBN D 4 .   ? 89.866  73.608  43.136 1.00 215.97 ? 702 LBN A C27 1 
HETATM 3909 C C28 . LBN D 4 .   ? 88.788  74.674  43.066 1.00 255.09 ? 702 LBN A C28 1 
HETATM 3910 C C29 . LBN D 4 .   ? 88.836  75.624  44.216 1.00 222.07 ? 702 LBN A C29 1 
HETATM 3911 C C30 . LBN D 4 .   ? 88.142  75.098  45.438 1.00 190.94 ? 702 LBN A C30 1 
HETATM 3912 C C31 . LBN D 4 .   ? 87.399  76.136  46.283 1.00 221.00 ? 702 LBN A C31 1 
HETATM 3913 C C32 . LBN D 4 .   ? 88.116  77.408  46.668 1.00 203.58 ? 702 LBN A C32 1 
HETATM 3914 C C33 . LBN D 4 .   ? 87.419  78.155  47.805 1.00 162.66 ? 702 LBN A C33 1 
HETATM 3915 C C34 . LBN D 4 .   ? 91.009  78.410  40.460 1.00 223.94 ? 702 LBN A C34 1 
HETATM 3916 O O7  . LBN D 4 .   ? 92.015  77.763  39.850 1.00 211.28 ? 702 LBN A O7  1 
HETATM 3917 C C35 . LBN D 4 .   ? 91.375  78.861  41.846 1.00 230.25 ? 702 LBN A C35 1 
HETATM 3918 O O8  . LBN D 4 .   ? 89.929  78.589  39.940 1.00 207.32 ? 702 LBN A O8  1 
HETATM 3919 C C36 . LBN D 4 .   ? 90.228  79.497  42.608 1.00 215.08 ? 702 LBN A C36 1 
HETATM 3920 C C37 . LBN D 4 .   ? 89.906  80.906  42.125 1.00 182.53 ? 702 LBN A C37 1 
HETATM 3921 C C38 . LBN D 4 .   ? 88.711  81.527  42.752 1.00 163.73 ? 702 LBN A C38 1 
HETATM 3922 C C39 . LBN D 4 .   ? 89.000  82.073  44.140 1.00 222.64 ? 702 LBN A C39 1 
HETATM 3923 C C40 . LBN D 4 .   ? 87.810  82.743  44.818 1.00 282.20 ? 702 LBN A C40 1 
HETATM 3924 C C41 . LBN D 4 .   ? 87.872  82.817  46.337 1.00 301.99 ? 702 LBN A C41 1 
HETATM 3925 C C42 . LBN D 4 .   ? 87.077  83.969  46.873 1.00 276.26 ? 702 LBN A C42 1 
HETATM 3926 C C1  . CLR E 3 .   ? 88.537  78.279  62.239 1.00 234.58 ? 601 CLR B C1  1 
HETATM 3927 C C2  . CLR E 3 .   ? 88.370  77.901  63.725 1.00 305.25 ? 601 CLR B C2  1 
HETATM 3928 C C3  . CLR E 3 .   ? 87.157  78.530  64.391 1.00 289.89 ? 601 CLR B C3  1 
HETATM 3929 C C4  . CLR E 3 .   ? 85.910  78.319  63.547 1.00 236.09 ? 601 CLR B C4  1 
HETATM 3930 C C5  . CLR E 3 .   ? 86.115  78.740  62.099 1.00 178.78 ? 601 CLR B C5  1 
HETATM 3931 C C6  . CLR E 3 .   ? 85.310  79.628  61.550 1.00 182.27 ? 601 CLR B C6  1 
HETATM 3932 C C7  . CLR E 3 .   ? 85.291  79.951  60.102 1.00 185.64 ? 601 CLR B C7  1 
HETATM 3933 C C8  . CLR E 3 .   ? 86.190  79.090  59.235 1.00 130.38 ? 601 CLR B C8  1 
HETATM 3934 C C9  . CLR E 3 .   ? 87.508  78.784  59.963 1.00 148.09 ? 601 CLR B C9  1 
HETATM 3935 C C10 . CLR E 3 .   ? 87.279  78.089  61.344 1.00 182.28 ? 601 CLR B C10 1 
HETATM 3936 C C11 . CLR E 3 .   ? 88.511  78.087  59.007 1.00 186.46 ? 601 CLR B C11 1 
HETATM 3937 C C12 . CLR E 3 .   ? 88.687  78.794  57.639 1.00 170.29 ? 601 CLR B C12 1 
HETATM 3938 C C13 . CLR E 3 .   ? 87.374  79.095  56.913 1.00 159.78 ? 601 CLR B C13 1 
HETATM 3939 C C14 . CLR E 3 .   ? 86.494  79.844  57.942 1.00 181.69 ? 601 CLR B C14 1 
HETATM 3940 C C15 . CLR E 3 .   ? 85.329  80.419  57.138 1.00 227.61 ? 601 CLR B C15 1 
HETATM 3941 C C16 . CLR E 3 .   ? 85.880  80.590  55.715 1.00 154.18 ? 601 CLR B C16 1 
HETATM 3942 C C17 . CLR E 3 .   ? 87.364  80.129  55.741 1.00 173.38 ? 601 CLR B C17 1 
HETATM 3943 C C18 . CLR E 3 .   ? 86.769  77.788  56.429 1.00 191.41 ? 601 CLR B C18 1 
HETATM 3944 C C19 . CLR E 3 .   ? 86.895  76.602  61.177 1.00 204.57 ? 601 CLR B C19 1 
HETATM 3945 C C20 . CLR E 3 .   ? 87.812  79.775  54.303 1.00 227.95 ? 601 CLR B C20 1 
HETATM 3946 C C21 . CLR E 3 .   ? 89.166  79.072  54.210 1.00 235.65 ? 601 CLR B C21 1 
HETATM 3947 C C22 . CLR E 3 .   ? 87.820  81.038  53.403 1.00 304.18 ? 601 CLR B C22 1 
HETATM 3948 C C23 . CLR E 3 .   ? 87.038  80.944  52.116 1.00 367.11 ? 601 CLR B C23 1 
HETATM 3949 C C24 . CLR E 3 .   ? 85.581  81.426  52.253 1.00 374.94 ? 601 CLR B C24 1 
HETATM 3950 C C25 . CLR E 3 .   ? 85.246  82.916  52.044 1.00 306.73 ? 601 CLR B C25 1 
HETATM 3951 C C26 . CLR E 3 .   ? 85.987  83.504  50.863 1.00 247.04 ? 601 CLR B C26 1 
HETATM 3952 C C27 . CLR E 3 .   ? 85.513  83.750  53.295 1.00 274.69 ? 601 CLR B C27 1 
HETATM 3953 O O1  . CLR E 3 .   ? 86.938  77.974  65.701 1.00 252.42 ? 601 CLR B O1  1 
HETATM 3954 C C1  . CLR F 3 .   ? 75.689  83.038  61.465 1.00 235.29 ? 602 CLR B C1  1 
HETATM 3955 C C2  . CLR F 3 .   ? 75.405  82.505  62.885 1.00 219.58 ? 602 CLR B C2  1 
HETATM 3956 C C3  . CLR F 3 .   ? 73.931  82.163  63.043 1.00 288.13 ? 602 CLR B C3  1 
HETATM 3957 C C4  . CLR F 3 .   ? 73.534  81.137  61.987 1.00 323.68 ? 602 CLR B C4  1 
HETATM 3958 C C5  . CLR F 3 .   ? 73.837  81.586  60.562 1.00 298.98 ? 602 CLR B C5  1 
HETATM 3959 C C6  . CLR F 3 .   ? 72.899  81.505  59.618 1.00 264.86 ? 602 CLR B C6  1 
HETATM 3960 C C7  . CLR F 3 .   ? 73.036  82.068  58.233 1.00 235.18 ? 602 CLR B C7  1 
HETATM 3961 C C8  . CLR F 3 .   ? 74.489  82.275  57.795 1.00 165.68 ? 602 CLR B C8  1 
HETATM 3962 C C9  . CLR F 3 .   ? 75.256  82.950  58.945 1.00 187.74 ? 602 CLR B C9  1 
HETATM 3963 C C10 . CLR F 3 .   ? 75.253  82.123  60.277 1.00 239.15 ? 602 CLR B C10 1 
HETATM 3964 C C11 . CLR F 3 .   ? 76.645  83.413  58.470 1.00 216.13 ? 602 CLR B C11 1 
HETATM 3965 C C12 . CLR F 3 .   ? 76.616  84.275  57.196 1.00 218.33 ? 602 CLR B C12 1 
HETATM 3966 C C13 . CLR F 3 .   ? 75.916  83.582  56.016 1.00 179.40 ? 602 CLR B C13 1 
HETATM 3967 C C14 . CLR F 3 .   ? 74.531  83.162  56.552 1.00 183.13 ? 602 CLR B C14 1 
HETATM 3968 C C15 . CLR F 3 .   ? 73.815  82.733  55.277 1.00 178.96 ? 602 CLR B C15 1 
HETATM 3969 C C16 . CLR F 3 .   ? 74.265  83.768  54.225 1.00 173.02 ? 602 CLR B C16 1 
HETATM 3970 C C17 . CLR F 3 .   ? 75.511  84.496  54.806 1.00 201.23 ? 602 CLR B C17 1 
HETATM 3971 C C18 . CLR F 3 .   ? 76.746  82.410  55.482 1.00 122.76 ? 602 CLR B C18 1 
HETATM 3972 C C19 . CLR F 3 .   ? 76.213  80.914  60.189 1.00 228.66 ? 602 CLR B C19 1 
HETATM 3973 C C20 . CLR F 3 .   ? 76.555  84.936  53.740 1.00 239.75 ? 602 CLR B C20 1 
HETATM 3974 C C21 . CLR F 3 .   ? 77.607  85.901  54.309 1.00 280.71 ? 602 CLR B C21 1 
HETATM 3975 C C22 . CLR F 3 .   ? 75.896  85.581  52.501 1.00 226.90 ? 602 CLR B C22 1 
HETATM 3976 C C23 . CLR F 3 .   ? 76.806  85.755  51.289 1.00 263.62 ? 602 CLR B C23 1 
HETATM 3977 C C24 . CLR F 3 .   ? 76.099  86.201  50.029 1.00 272.36 ? 602 CLR B C24 1 
HETATM 3978 C C25 . CLR F 3 .   ? 76.836  85.897  48.703 1.00 288.93 ? 602 CLR B C25 1 
HETATM 3979 C C26 . CLR F 3 .   ? 78.290  86.383  48.726 1.00 274.69 ? 602 CLR B C26 1 
HETATM 3980 C C27 . CLR F 3 .   ? 76.083  86.475  47.493 1.00 242.51 ? 602 CLR B C27 1 
HETATM 3981 O O1  . CLR F 3 .   ? 73.612  81.672  64.364 1.00 184.69 ? 602 CLR B O1  1 
HETATM 3982 C C1  . LBN G 4 .   ? 73.596  91.248  36.505 1.00 262.77 ? 603 LBN B C1  1 
HETATM 3983 N N1  . LBN G 4 .   ? 72.078  86.908  31.689 1.00 354.97 ? 603 LBN B N1  1 
HETATM 3984 P P1  . LBN G 4 .   ? 74.407  89.765  34.427 1.00 260.50 ? 603 LBN B P1  1 
HETATM 3985 C C2  . LBN G 4 .   ? 73.317  90.493  37.786 1.00 283.17 ? 603 LBN B C2  1 
HETATM 3986 C C3  . LBN G 4 .   ? 74.099  91.009  38.974 1.00 295.77 ? 603 LBN B C3  1 
HETATM 3987 C C6  . LBN G 4 .   ? 72.856  87.245  32.953 1.00 368.23 ? 603 LBN B C6  1 
HETATM 3988 O O1  . LBN G 4 .   ? 74.691  90.586  35.787 1.00 281.88 ? 603 LBN B O1  1 
HETATM 3989 C C9  . LBN G 4 .   ? 72.263  88.302  33.854 1.00 336.47 ? 603 LBN B C9  1 
HETATM 3990 O O2  . LBN G 4 .   ? 73.233  88.752  34.847 1.00 312.27 ? 603 LBN B O2  1 
HETATM 3991 C C12 . LBN G 4 .   ? 72.070  88.081  30.755 1.00 315.00 ? 603 LBN B C12 1 
HETATM 3992 O O3  . LBN G 4 .   ? 75.572  88.868  34.106 1.00 184.83 ? 603 LBN B O3  1 
HETATM 3993 C C15 . LBN G 4 .   ? 70.660  86.540  32.021 1.00 365.22 ? 603 LBN B C15 1 
HETATM 3994 O O4  . LBN G 4 .   ? 73.918  90.760  33.408 1.00 276.42 ? 603 LBN B O4  1 
HETATM 3995 C C18 . LBN G 4 .   ? 72.748  85.746  31.010 1.00 387.31 ? 603 LBN B C18 1 
HETATM 3996 C C25 . LBN G 4 .   ? 76.478  91.211  38.792 1.00 331.66 ? 603 LBN B C25 1 
HETATM 3997 O O5  . LBN G 4 .   ? 75.418  90.414  38.927 1.00 337.77 ? 603 LBN B O5  1 
HETATM 3998 C C26 . LBN G 4 .   ? 77.772  90.455  38.965 1.00 337.64 ? 603 LBN B C26 1 
HETATM 3999 O O6  . LBN G 4 .   ? 76.431  92.391  38.562 1.00 341.61 ? 603 LBN B O6  1 
HETATM 4000 C C27 . LBN G 4 .   ? 78.486  90.220  37.661 1.00 355.73 ? 603 LBN B C27 1 
HETATM 4001 C C28 . LBN G 4 .   ? 79.978  89.913  37.817 1.00 338.82 ? 603 LBN B C28 1 
HETATM 4002 C C29 . LBN G 4 .   ? 80.316  88.681  38.659 1.00 237.64 ? 603 LBN B C29 1 
HETATM 4003 C C34 . LBN G 4 .   ? 71.044  89.677  37.686 1.00 292.92 ? 603 LBN B C34 1 
HETATM 4004 O O7  . LBN G 4 .   ? 71.920  90.573  38.157 1.00 296.32 ? 603 LBN B O7  1 
HETATM 4005 C C35 . LBN G 4 .   ? 70.756  88.618  38.670 1.00 226.90 ? 603 LBN B C35 1 
HETATM 4006 O O8  . LBN G 4 .   ? 70.552  89.751  36.603 1.00 315.24 ? 603 LBN B O8  1 
HETATM 4007 C C36 . LBN G 4 .   ? 70.174  89.061  39.995 1.00 301.21 ? 603 LBN B C36 1 
HETATM 4008 C C37 . LBN G 4 .   ? 71.197  89.299  41.105 1.00 239.90 ? 603 LBN B C37 1 
HETATM 4009 C C38 . LBN G 4 .   ? 71.831  88.071  41.689 1.00 199.43 ? 603 LBN B C38 1 
HETATM 4010 C C39 . LBN G 4 .   ? 73.146  88.300  42.414 1.00 218.80 ? 603 LBN B C39 1 
HETATM 4011 C C40 . LBN G 4 .   ? 73.916  87.015  42.733 1.00 229.07 ? 603 LBN B C40 1 
HETATM 4012 C C41 . LBN G 4 .   ? 75.159  87.213  43.573 1.00 235.53 ? 603 LBN B C41 1 
HETATM 4013 C C42 . LBN G 4 .   ? 76.178  86.117  43.460 1.00 224.57 ? 603 LBN B C42 1 
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