data_8KDI
# 
_entry.id   8KDI 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8KDI         pdb_00008kdi 10.2210/pdb8kdi/pdb 
WWPDB D_1300040169 ?            ?                   
EMDB  EMD-37137    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1  'Structure model' 1 0 2025-02-12 ? 
2  'EM metadata'     1 0 2025-02-12 ? 
3  FSC               1 0 2025-02-12 ? 
4  'Half map'        1 0 2025-02-12 1 
5  'Half map'        1 0 2025-02-12 2 
6  Image             1 0 2025-02-12 ? 
7  Mask              1 0 2025-02-12 ? 
8  'Primary map'     1 0 2025-02-12 ? 
9  'Structure model' 1 1 2025-02-26 ? 
10 'EM metadata'     1 1 2025-02-26 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 Mask              repository 'Initial release' ? ? 
8 8 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 9  'Structure model' 'Data collection'      
2 9  'Structure model' 'Database references'  
3 10 'EM metadata'     'Database references'  
4 10 'EM metadata'     'Experimental summary' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 9  'Structure model' citation        
2 9  'Structure model' citation_author 
3 9  'Structure model' em_admin        
4 10 'EM metadata'     citation        
5 10 'EM metadata'     citation_author 
6 10 'EM metadata'     em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  9  'Structure model' '_citation.country'                 
2  9  'Structure model' '_citation.journal_abbrev'          
3  9  'Structure model' '_citation.journal_id_CSD'          
4  9  'Structure model' '_citation.journal_id_ISSN'         
5  9  'Structure model' '_citation.journal_volume'          
6  9  'Structure model' '_citation.page_first'              
7  9  'Structure model' '_citation.page_last'               
8  9  'Structure model' '_citation.pdbx_database_id_DOI'    
9  9  'Structure model' '_citation.pdbx_database_id_PubMed' 
10 9  'Structure model' '_citation.title'                   
11 9  'Structure model' '_citation.year'                    
12 9  'Structure model' '_em_admin.last_update'             
13 10 'EM metadata'     '_citation.country'                 
14 10 'EM metadata'     '_citation.journal_abbrev'          
15 10 'EM metadata'     '_citation.journal_id_CSD'          
16 10 'EM metadata'     '_citation.journal_id_ISSN'         
17 10 'EM metadata'     '_citation.journal_volume'          
18 10 'EM metadata'     '_citation.page_first'              
19 10 'EM metadata'     '_citation.page_last'               
20 10 'EM metadata'     '_citation.pdbx_database_id_DOI'    
21 10 'EM metadata'     '_citation.pdbx_database_id_PubMed' 
22 10 'EM metadata'     '_citation.title'                   
23 10 'EM metadata'     '_citation.year'                    
24 10 'EM metadata'     '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8KDI 
_pdbx_database_status.recvd_initial_deposition_date   2023-08-09 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'Structure of apo inward-open LAT1-CD98hc-Fab170 in nanodisc, consensus map' EMD-37137 'associated EM volume' 
EMDB 'Structure of apo inward-open LAT1-CD98h in nanodisc, focused on TMD'        EMD-37138 'other EM volume'      
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              ri.yon.df@yokohama-cu.ac.jp 
_pdbx_contact_author.name_first         Yongchan 
_pdbx_contact_author.name_last          Lee 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1507-805X 
# 
_audit_author.name               'Lee, Y.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                1635 
_citation.page_last                 1635 
_citation.title                     'Structural basis of anticancer drug recognition and amino acid transport by LAT1.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-56903-w 
_citation.pdbx_database_id_PubMed   39952931 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Lee, Y.'          1  0000-0002-1507-805X 
primary 'Jin, C.'          2  ?                   
primary 'Ohgaki, R.'       3  0000-0002-6894-7239 
primary 'Xu, M.'           4  ?                   
primary 'Ogasawara, S.'    5  0000-0001-6908-9953 
primary 'Warshamanage, R.' 6  ?                   
primary 'Yamashita, K.'    7  0000-0002-5442-7582 
primary 'Murshudov, G.'    8  ?                   
primary 'Nureki, O.'       9  0000-0003-1813-7008 
primary 'Murata, T.'       10 0000-0002-5748-4670 
primary 'Kanai, Y.'        11 0000-0001-8126-286X 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man '4F2 cell-surface antigen heavy chain'                  68069.625 1 ? ? ? ? 
2 polymer     man 'Large neutral amino acids transporter small subunit 1' 56043.746 1 ? ? ? ? 
3 polymer     nat 'Fab170 light chain'                                    24355.986 1 ? ? ? ? 
4 polymer     nat 'Fab170 heavy chain'                                    24981.906 1 ? ? ? ? 
5 non-polymer syn 2-acetamido-2-deoxy-beta-D-glucopyranose                221.208   4 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Glycoprotein, 4F2hc,4F2 heavy chain antigen,Lymphocyte activation antigen 4F2 large subunit,Solute carrier family 3 member 2' 
2 
;4F2 light chain,4F2LC,CD98 light chain,Integral membrane protein E16,L-type amino acid transporter 1,hLAT1,Solute carrier family 7 member 5,y+ system cationic amino acid transporter
;
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;GSELQPPEASIAVVSIPRQLPGSHSEAGVQGLSAGDDSELGSHCVAQTGLELLASGDPLPSASQNAEMIETGSDCVTQAG
LQLLASSDPPALASKNAEVTGTMSQDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEKNGLVKIKVAEDEAEAAAAA
KFTGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAG
NLAGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWF
STQVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQILSLLESNKDLL
LTSSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAAL
PGQPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQ
NERFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPYAA
;
;GSELQPPEASIAVVSIPRQLPGSHSEAGVQGLSAGDDSELGSHCVAQTGLELLASGDPLPSASQNAEMIETGSDCVTQAG
LQLLASSDPPALASKNAEVTGTMSQDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEKNGLVKIKVAEDEAEAAAAA
KFTGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAG
NLAGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWF
STQVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQILSLLESNKDLL
LTSSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAAL
PGQPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQ
NERFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPYAA
;
A ? 
2 'polypeptide(L)' no no 
;MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAG
SPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPL
FPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV
GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHL
GVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFF
SFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN
KPKWLLQGIFSTTVLCQKLMQVVPQETDYKDDDDK
;
;MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAG
SPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPL
FPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV
GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHL
GVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFF
SFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN
KPKWLLQGIFSTTVLCQKLMQVVPQETDYKDDDDK
;
B ? 
3 'polypeptide(L)' no no 
;DIVLTQSPSSLAMSVGQKVTMNCKSSQSLLNNNNQKNYLAWYQQKPGQSPKLLVYFTSTRESGVPDRFIGSGSGTDFTLT
ISSVQAEDLALYYCQQHYTIPPTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSE
RQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC
;
;DIVLTQSPSSLAMSVGQKVTMNCKSSQSLLNNNNQKNYLAWYQQKPGQSPKLLVYFTSTRESGVPDRFIGSGSGTDFTLT
ISSVQAEDLALYYCQQHYTIPPTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSE
RQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC
;
L ? 
4 'polypeptide(L)' no no 
;EVQLQQSGAELVKPGASVNLSCKASGYTFTNYWMHWVRLRPGQGLEWIGEIDPSDSYSYYSQNFKGKATLTVDQSSNTAY
LQLTSLTSEDSAVYYCARGRQTYYPWFPYWGQGTLVTVSAAKTTPPSDYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVT
WNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRDCGCKPCICT
;
;EVQLQQSGAELVKPGASVNLSCKASGYTFTNYWMHWVRLRPGQGLEWIGEIDPSDSYSYYSQNFKGKATLTVDQSSNTAY
LQLTSLTSEDSAVYYCARGRQTYYPWFPYWGQGTLVTVSAAKTTPPSDYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVT
WNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRDCGCKPCICT
;
H ? 
# 
_pdbx_entity_nonpoly.entity_id   5 
_pdbx_entity_nonpoly.name        2-acetamido-2-deoxy-beta-D-glucopyranose 
_pdbx_entity_nonpoly.comp_id     NAG 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   SER n 
1 3   GLU n 
1 4   LEU n 
1 5   GLN n 
1 6   PRO n 
1 7   PRO n 
1 8   GLU n 
1 9   ALA n 
1 10  SER n 
1 11  ILE n 
1 12  ALA n 
1 13  VAL n 
1 14  VAL n 
1 15  SER n 
1 16  ILE n 
1 17  PRO n 
1 18  ARG n 
1 19  GLN n 
1 20  LEU n 
1 21  PRO n 
1 22  GLY n 
1 23  SER n 
1 24  HIS n 
1 25  SER n 
1 26  GLU n 
1 27  ALA n 
1 28  GLY n 
1 29  VAL n 
1 30  GLN n 
1 31  GLY n 
1 32  LEU n 
1 33  SER n 
1 34  ALA n 
1 35  GLY n 
1 36  ASP n 
1 37  ASP n 
1 38  SER n 
1 39  GLU n 
1 40  LEU n 
1 41  GLY n 
1 42  SER n 
1 43  HIS n 
1 44  CYS n 
1 45  VAL n 
1 46  ALA n 
1 47  GLN n 
1 48  THR n 
1 49  GLY n 
1 50  LEU n 
1 51  GLU n 
1 52  LEU n 
1 53  LEU n 
1 54  ALA n 
1 55  SER n 
1 56  GLY n 
1 57  ASP n 
1 58  PRO n 
1 59  LEU n 
1 60  PRO n 
1 61  SER n 
1 62  ALA n 
1 63  SER n 
1 64  GLN n 
1 65  ASN n 
1 66  ALA n 
1 67  GLU n 
1 68  MET n 
1 69  ILE n 
1 70  GLU n 
1 71  THR n 
1 72  GLY n 
1 73  SER n 
1 74  ASP n 
1 75  CYS n 
1 76  VAL n 
1 77  THR n 
1 78  GLN n 
1 79  ALA n 
1 80  GLY n 
1 81  LEU n 
1 82  GLN n 
1 83  LEU n 
1 84  LEU n 
1 85  ALA n 
1 86  SER n 
1 87  SER n 
1 88  ASP n 
1 89  PRO n 
1 90  PRO n 
1 91  ALA n 
1 92  LEU n 
1 93  ALA n 
1 94  SER n 
1 95  LYS n 
1 96  ASN n 
1 97  ALA n 
1 98  GLU n 
1 99  VAL n 
1 100 THR n 
1 101 GLY n 
1 102 THR n 
1 103 MET n 
1 104 SER n 
1 105 GLN n 
1 106 ASP n 
1 107 THR n 
1 108 GLU n 
1 109 VAL n 
1 110 ASP n 
1 111 MET n 
1 112 LYS n 
1 113 GLU n 
1 114 VAL n 
1 115 GLU n 
1 116 LEU n 
1 117 ASN n 
1 118 GLU n 
1 119 LEU n 
1 120 GLU n 
1 121 PRO n 
1 122 GLU n 
1 123 LYS n 
1 124 GLN n 
1 125 PRO n 
1 126 MET n 
1 127 ASN n 
1 128 ALA n 
1 129 ALA n 
1 130 SER n 
1 131 GLY n 
1 132 ALA n 
1 133 ALA n 
1 134 MET n 
1 135 SER n 
1 136 LEU n 
1 137 ALA n 
1 138 GLY n 
1 139 ALA n 
1 140 GLU n 
1 141 LYS n 
1 142 ASN n 
1 143 GLY n 
1 144 LEU n 
1 145 VAL n 
1 146 LYS n 
1 147 ILE n 
1 148 LYS n 
1 149 VAL n 
1 150 ALA n 
1 151 GLU n 
1 152 ASP n 
1 153 GLU n 
1 154 ALA n 
1 155 GLU n 
1 156 ALA n 
1 157 ALA n 
1 158 ALA n 
1 159 ALA n 
1 160 ALA n 
1 161 LYS n 
1 162 PHE n 
1 163 THR n 
1 164 GLY n 
1 165 LEU n 
1 166 SER n 
1 167 LYS n 
1 168 GLU n 
1 169 GLU n 
1 170 LEU n 
1 171 LEU n 
1 172 LYS n 
1 173 VAL n 
1 174 ALA n 
1 175 GLY n 
1 176 SER n 
1 177 PRO n 
1 178 GLY n 
1 179 TRP n 
1 180 VAL n 
1 181 ARG n 
1 182 THR n 
1 183 ARG n 
1 184 TRP n 
1 185 ALA n 
1 186 LEU n 
1 187 LEU n 
1 188 LEU n 
1 189 LEU n 
1 190 PHE n 
1 191 TRP n 
1 192 LEU n 
1 193 GLY n 
1 194 TRP n 
1 195 LEU n 
1 196 GLY n 
1 197 MET n 
1 198 LEU n 
1 199 ALA n 
1 200 GLY n 
1 201 ALA n 
1 202 VAL n 
1 203 VAL n 
1 204 ILE n 
1 205 ILE n 
1 206 VAL n 
1 207 ARG n 
1 208 ALA n 
1 209 PRO n 
1 210 ARG n 
1 211 CYS n 
1 212 ARG n 
1 213 GLU n 
1 214 LEU n 
1 215 PRO n 
1 216 ALA n 
1 217 GLN n 
1 218 LYS n 
1 219 TRP n 
1 220 TRP n 
1 221 HIS n 
1 222 THR n 
1 223 GLY n 
1 224 ALA n 
1 225 LEU n 
1 226 TYR n 
1 227 ARG n 
1 228 ILE n 
1 229 GLY n 
1 230 ASP n 
1 231 LEU n 
1 232 GLN n 
1 233 ALA n 
1 234 PHE n 
1 235 GLN n 
1 236 GLY n 
1 237 HIS n 
1 238 GLY n 
1 239 ALA n 
1 240 GLY n 
1 241 ASN n 
1 242 LEU n 
1 243 ALA n 
1 244 GLY n 
1 245 LEU n 
1 246 LYS n 
1 247 GLY n 
1 248 ARG n 
1 249 LEU n 
1 250 ASP n 
1 251 TYR n 
1 252 LEU n 
1 253 SER n 
1 254 SER n 
1 255 LEU n 
1 256 LYS n 
1 257 VAL n 
1 258 LYS n 
1 259 GLY n 
1 260 LEU n 
1 261 VAL n 
1 262 LEU n 
1 263 GLY n 
1 264 PRO n 
1 265 ILE n 
1 266 HIS n 
1 267 LYS n 
1 268 ASN n 
1 269 GLN n 
1 270 LYS n 
1 271 ASP n 
1 272 ASP n 
1 273 VAL n 
1 274 ALA n 
1 275 GLN n 
1 276 THR n 
1 277 ASP n 
1 278 LEU n 
1 279 LEU n 
1 280 GLN n 
1 281 ILE n 
1 282 ASP n 
1 283 PRO n 
1 284 ASN n 
1 285 PHE n 
1 286 GLY n 
1 287 SER n 
1 288 LYS n 
1 289 GLU n 
1 290 ASP n 
1 291 PHE n 
1 292 ASP n 
1 293 SER n 
1 294 LEU n 
1 295 LEU n 
1 296 GLN n 
1 297 SER n 
1 298 ALA n 
1 299 LYS n 
1 300 LYS n 
1 301 LYS n 
1 302 SER n 
1 303 ILE n 
1 304 ARG n 
1 305 VAL n 
1 306 ILE n 
1 307 LEU n 
1 308 ASP n 
1 309 LEU n 
1 310 THR n 
1 311 PRO n 
1 312 ASN n 
1 313 TYR n 
1 314 ARG n 
1 315 GLY n 
1 316 GLU n 
1 317 ASN n 
1 318 SER n 
1 319 TRP n 
1 320 PHE n 
1 321 SER n 
1 322 THR n 
1 323 GLN n 
1 324 VAL n 
1 325 ASP n 
1 326 THR n 
1 327 VAL n 
1 328 ALA n 
1 329 THR n 
1 330 LYS n 
1 331 VAL n 
1 332 LYS n 
1 333 ASP n 
1 334 ALA n 
1 335 LEU n 
1 336 GLU n 
1 337 PHE n 
1 338 TRP n 
1 339 LEU n 
1 340 GLN n 
1 341 ALA n 
1 342 GLY n 
1 343 VAL n 
1 344 ASP n 
1 345 GLY n 
1 346 PHE n 
1 347 GLN n 
1 348 VAL n 
1 349 ARG n 
1 350 ASP n 
1 351 ILE n 
1 352 GLU n 
1 353 ASN n 
1 354 LEU n 
1 355 LYS n 
1 356 ASP n 
1 357 ALA n 
1 358 SER n 
1 359 SER n 
1 360 PHE n 
1 361 LEU n 
1 362 ALA n 
1 363 GLU n 
1 364 TRP n 
1 365 GLN n 
1 366 ASN n 
1 367 ILE n 
1 368 THR n 
1 369 LYS n 
1 370 GLY n 
1 371 PHE n 
1 372 SER n 
1 373 GLU n 
1 374 ASP n 
1 375 ARG n 
1 376 LEU n 
1 377 LEU n 
1 378 ILE n 
1 379 ALA n 
1 380 GLY n 
1 381 THR n 
1 382 ASN n 
1 383 SER n 
1 384 SER n 
1 385 ASP n 
1 386 LEU n 
1 387 GLN n 
1 388 GLN n 
1 389 ILE n 
1 390 LEU n 
1 391 SER n 
1 392 LEU n 
1 393 LEU n 
1 394 GLU n 
1 395 SER n 
1 396 ASN n 
1 397 LYS n 
1 398 ASP n 
1 399 LEU n 
1 400 LEU n 
1 401 LEU n 
1 402 THR n 
1 403 SER n 
1 404 SER n 
1 405 TYR n 
1 406 LEU n 
1 407 SER n 
1 408 ASP n 
1 409 SER n 
1 410 GLY n 
1 411 SER n 
1 412 THR n 
1 413 GLY n 
1 414 GLU n 
1 415 HIS n 
1 416 THR n 
1 417 LYS n 
1 418 SER n 
1 419 LEU n 
1 420 VAL n 
1 421 THR n 
1 422 GLN n 
1 423 TYR n 
1 424 LEU n 
1 425 ASN n 
1 426 ALA n 
1 427 THR n 
1 428 GLY n 
1 429 ASN n 
1 430 ARG n 
1 431 TRP n 
1 432 CYS n 
1 433 SER n 
1 434 TRP n 
1 435 SER n 
1 436 LEU n 
1 437 SER n 
1 438 GLN n 
1 439 ALA n 
1 440 ARG n 
1 441 LEU n 
1 442 LEU n 
1 443 THR n 
1 444 SER n 
1 445 PHE n 
1 446 LEU n 
1 447 PRO n 
1 448 ALA n 
1 449 GLN n 
1 450 LEU n 
1 451 LEU n 
1 452 ARG n 
1 453 LEU n 
1 454 TYR n 
1 455 GLN n 
1 456 LEU n 
1 457 MET n 
1 458 LEU n 
1 459 PHE n 
1 460 THR n 
1 461 LEU n 
1 462 PRO n 
1 463 GLY n 
1 464 THR n 
1 465 PRO n 
1 466 VAL n 
1 467 PHE n 
1 468 SER n 
1 469 TYR n 
1 470 GLY n 
1 471 ASP n 
1 472 GLU n 
1 473 ILE n 
1 474 GLY n 
1 475 LEU n 
1 476 ASP n 
1 477 ALA n 
1 478 ALA n 
1 479 ALA n 
1 480 LEU n 
1 481 PRO n 
1 482 GLY n 
1 483 GLN n 
1 484 PRO n 
1 485 MET n 
1 486 GLU n 
1 487 ALA n 
1 488 PRO n 
1 489 VAL n 
1 490 MET n 
1 491 LEU n 
1 492 TRP n 
1 493 ASP n 
1 494 GLU n 
1 495 SER n 
1 496 SER n 
1 497 PHE n 
1 498 PRO n 
1 499 ASP n 
1 500 ILE n 
1 501 PRO n 
1 502 GLY n 
1 503 ALA n 
1 504 VAL n 
1 505 SER n 
1 506 ALA n 
1 507 ASN n 
1 508 MET n 
1 509 THR n 
1 510 VAL n 
1 511 LYS n 
1 512 GLY n 
1 513 GLN n 
1 514 SER n 
1 515 GLU n 
1 516 ASP n 
1 517 PRO n 
1 518 GLY n 
1 519 SER n 
1 520 LEU n 
1 521 LEU n 
1 522 SER n 
1 523 LEU n 
1 524 PHE n 
1 525 ARG n 
1 526 ARG n 
1 527 LEU n 
1 528 SER n 
1 529 ASP n 
1 530 GLN n 
1 531 ARG n 
1 532 SER n 
1 533 LYS n 
1 534 GLU n 
1 535 ARG n 
1 536 SER n 
1 537 LEU n 
1 538 LEU n 
1 539 HIS n 
1 540 GLY n 
1 541 ASP n 
1 542 PHE n 
1 543 HIS n 
1 544 ALA n 
1 545 PHE n 
1 546 SER n 
1 547 ALA n 
1 548 GLY n 
1 549 PRO n 
1 550 GLY n 
1 551 LEU n 
1 552 PHE n 
1 553 SER n 
1 554 TYR n 
1 555 ILE n 
1 556 ARG n 
1 557 HIS n 
1 558 TRP n 
1 559 ASP n 
1 560 GLN n 
1 561 ASN n 
1 562 GLU n 
1 563 ARG n 
1 564 PHE n 
1 565 LEU n 
1 566 VAL n 
1 567 VAL n 
1 568 LEU n 
1 569 ASN n 
1 570 PHE n 
1 571 GLY n 
1 572 ASP n 
1 573 VAL n 
1 574 GLY n 
1 575 LEU n 
1 576 SER n 
1 577 ALA n 
1 578 GLY n 
1 579 LEU n 
1 580 GLN n 
1 581 ALA n 
1 582 SER n 
1 583 ASP n 
1 584 LEU n 
1 585 PRO n 
1 586 ALA n 
1 587 SER n 
1 588 ALA n 
1 589 SER n 
1 590 LEU n 
1 591 PRO n 
1 592 ALA n 
1 593 LYS n 
1 594 ALA n 
1 595 ASP n 
1 596 LEU n 
1 597 LEU n 
1 598 LEU n 
1 599 SER n 
1 600 THR n 
1 601 GLN n 
1 602 PRO n 
1 603 GLY n 
1 604 ARG n 
1 605 GLU n 
1 606 GLU n 
1 607 GLY n 
1 608 SER n 
1 609 PRO n 
1 610 LEU n 
1 611 GLU n 
1 612 LEU n 
1 613 GLU n 
1 614 ARG n 
1 615 LEU n 
1 616 LYS n 
1 617 LEU n 
1 618 GLU n 
1 619 PRO n 
1 620 HIS n 
1 621 GLU n 
1 622 GLY n 
1 623 LEU n 
1 624 LEU n 
1 625 LEU n 
1 626 ARG n 
1 627 PHE n 
1 628 PRO n 
1 629 TYR n 
1 630 ALA n 
1 631 ALA n 
2 1   MET n 
2 2   ALA n 
2 3   GLY n 
2 4   ALA n 
2 5   GLY n 
2 6   PRO n 
2 7   LYS n 
2 8   ARG n 
2 9   ARG n 
2 10  ALA n 
2 11  LEU n 
2 12  ALA n 
2 13  ALA n 
2 14  PRO n 
2 15  ALA n 
2 16  ALA n 
2 17  GLU n 
2 18  GLU n 
2 19  LYS n 
2 20  GLU n 
2 21  GLU n 
2 22  ALA n 
2 23  ARG n 
2 24  GLU n 
2 25  LYS n 
2 26  MET n 
2 27  LEU n 
2 28  ALA n 
2 29  ALA n 
2 30  LYS n 
2 31  SER n 
2 32  ALA n 
2 33  ASP n 
2 34  GLY n 
2 35  SER n 
2 36  ALA n 
2 37  PRO n 
2 38  ALA n 
2 39  GLY n 
2 40  GLU n 
2 41  GLY n 
2 42  GLU n 
2 43  GLY n 
2 44  VAL n 
2 45  THR n 
2 46  LEU n 
2 47  GLN n 
2 48  ARG n 
2 49  ASN n 
2 50  ILE n 
2 51  THR n 
2 52  LEU n 
2 53  LEU n 
2 54  ASN n 
2 55  GLY n 
2 56  VAL n 
2 57  ALA n 
2 58  ILE n 
2 59  ILE n 
2 60  VAL n 
2 61  GLY n 
2 62  THR n 
2 63  ILE n 
2 64  ILE n 
2 65  GLY n 
2 66  SER n 
2 67  GLY n 
2 68  ILE n 
2 69  PHE n 
2 70  VAL n 
2 71  THR n 
2 72  PRO n 
2 73  THR n 
2 74  GLY n 
2 75  VAL n 
2 76  LEU n 
2 77  LYS n 
2 78  GLU n 
2 79  ALA n 
2 80  GLY n 
2 81  SER n 
2 82  PRO n 
2 83  GLY n 
2 84  LEU n 
2 85  ALA n 
2 86  LEU n 
2 87  VAL n 
2 88  VAL n 
2 89  TRP n 
2 90  ALA n 
2 91  ALA n 
2 92  CYS n 
2 93  GLY n 
2 94  VAL n 
2 95  PHE n 
2 96  SER n 
2 97  ILE n 
2 98  VAL n 
2 99  GLY n 
2 100 ALA n 
2 101 LEU n 
2 102 CYS n 
2 103 TYR n 
2 104 ALA n 
2 105 GLU n 
2 106 LEU n 
2 107 GLY n 
2 108 THR n 
2 109 THR n 
2 110 ILE n 
2 111 SER n 
2 112 LYS n 
2 113 SER n 
2 114 GLY n 
2 115 GLY n 
2 116 ASP n 
2 117 TYR n 
2 118 ALA n 
2 119 TYR n 
2 120 MET n 
2 121 LEU n 
2 122 GLU n 
2 123 VAL n 
2 124 TYR n 
2 125 GLY n 
2 126 SER n 
2 127 LEU n 
2 128 PRO n 
2 129 ALA n 
2 130 PHE n 
2 131 LEU n 
2 132 LYS n 
2 133 LEU n 
2 134 TRP n 
2 135 ILE n 
2 136 GLU n 
2 137 LEU n 
2 138 LEU n 
2 139 ILE n 
2 140 ILE n 
2 141 ARG n 
2 142 PRO n 
2 143 SER n 
2 144 SER n 
2 145 GLN n 
2 146 TYR n 
2 147 ILE n 
2 148 VAL n 
2 149 ALA n 
2 150 LEU n 
2 151 VAL n 
2 152 PHE n 
2 153 ALA n 
2 154 THR n 
2 155 TYR n 
2 156 LEU n 
2 157 LEU n 
2 158 LYS n 
2 159 PRO n 
2 160 LEU n 
2 161 PHE n 
2 162 PRO n 
2 163 THR n 
2 164 CYS n 
2 165 PRO n 
2 166 VAL n 
2 167 PRO n 
2 168 GLU n 
2 169 GLU n 
2 170 ALA n 
2 171 ALA n 
2 172 LYS n 
2 173 LEU n 
2 174 VAL n 
2 175 ALA n 
2 176 CYS n 
2 177 LEU n 
2 178 CYS n 
2 179 VAL n 
2 180 LEU n 
2 181 LEU n 
2 182 LEU n 
2 183 THR n 
2 184 ALA n 
2 185 VAL n 
2 186 ASN n 
2 187 CYS n 
2 188 TYR n 
2 189 SER n 
2 190 VAL n 
2 191 LYS n 
2 192 ALA n 
2 193 ALA n 
2 194 THR n 
2 195 ARG n 
2 196 VAL n 
2 197 GLN n 
2 198 ASP n 
2 199 ALA n 
2 200 PHE n 
2 201 ALA n 
2 202 ALA n 
2 203 ALA n 
2 204 LYS n 
2 205 LEU n 
2 206 LEU n 
2 207 ALA n 
2 208 LEU n 
2 209 ALA n 
2 210 LEU n 
2 211 ILE n 
2 212 ILE n 
2 213 LEU n 
2 214 LEU n 
2 215 GLY n 
2 216 PHE n 
2 217 VAL n 
2 218 GLN n 
2 219 ILE n 
2 220 GLY n 
2 221 LYS n 
2 222 GLY n 
2 223 ASP n 
2 224 VAL n 
2 225 SER n 
2 226 ASN n 
2 227 LEU n 
2 228 ASP n 
2 229 PRO n 
2 230 ASN n 
2 231 PHE n 
2 232 SER n 
2 233 PHE n 
2 234 GLU n 
2 235 GLY n 
2 236 THR n 
2 237 LYS n 
2 238 LEU n 
2 239 ASP n 
2 240 VAL n 
2 241 GLY n 
2 242 ASN n 
2 243 ILE n 
2 244 VAL n 
2 245 LEU n 
2 246 ALA n 
2 247 LEU n 
2 248 TYR n 
2 249 SER n 
2 250 GLY n 
2 251 LEU n 
2 252 PHE n 
2 253 ALA n 
2 254 TYR n 
2 255 GLY n 
2 256 GLY n 
2 257 TRP n 
2 258 ASN n 
2 259 TYR n 
2 260 LEU n 
2 261 ASN n 
2 262 PHE n 
2 263 VAL n 
2 264 THR n 
2 265 GLU n 
2 266 GLU n 
2 267 MET n 
2 268 ILE n 
2 269 ASN n 
2 270 PRO n 
2 271 TYR n 
2 272 ARG n 
2 273 ASN n 
2 274 LEU n 
2 275 PRO n 
2 276 LEU n 
2 277 ALA n 
2 278 ILE n 
2 279 ILE n 
2 280 ILE n 
2 281 SER n 
2 282 LEU n 
2 283 PRO n 
2 284 ILE n 
2 285 VAL n 
2 286 THR n 
2 287 LEU n 
2 288 VAL n 
2 289 TYR n 
2 290 VAL n 
2 291 LEU n 
2 292 THR n 
2 293 ASN n 
2 294 LEU n 
2 295 ALA n 
2 296 TYR n 
2 297 PHE n 
2 298 THR n 
2 299 THR n 
2 300 LEU n 
2 301 SER n 
2 302 THR n 
2 303 GLU n 
2 304 GLN n 
2 305 MET n 
2 306 LEU n 
2 307 SER n 
2 308 SER n 
2 309 GLU n 
2 310 ALA n 
2 311 VAL n 
2 312 ALA n 
2 313 VAL n 
2 314 ASP n 
2 315 PHE n 
2 316 GLY n 
2 317 ASN n 
2 318 TYR n 
2 319 HIS n 
2 320 LEU n 
2 321 GLY n 
2 322 VAL n 
2 323 MET n 
2 324 SER n 
2 325 TRP n 
2 326 ILE n 
2 327 ILE n 
2 328 PRO n 
2 329 VAL n 
2 330 PHE n 
2 331 VAL n 
2 332 GLY n 
2 333 LEU n 
2 334 SER n 
2 335 CYS n 
2 336 PHE n 
2 337 GLY n 
2 338 SER n 
2 339 VAL n 
2 340 ASN n 
2 341 GLY n 
2 342 SER n 
2 343 LEU n 
2 344 PHE n 
2 345 THR n 
2 346 SER n 
2 347 SER n 
2 348 ARG n 
2 349 LEU n 
2 350 PHE n 
2 351 PHE n 
2 352 VAL n 
2 353 GLY n 
2 354 SER n 
2 355 ARG n 
2 356 GLU n 
2 357 GLY n 
2 358 HIS n 
2 359 LEU n 
2 360 PRO n 
2 361 SER n 
2 362 ILE n 
2 363 LEU n 
2 364 SER n 
2 365 MET n 
2 366 ILE n 
2 367 HIS n 
2 368 PRO n 
2 369 GLN n 
2 370 LEU n 
2 371 LEU n 
2 372 THR n 
2 373 PRO n 
2 374 VAL n 
2 375 PRO n 
2 376 SER n 
2 377 LEU n 
2 378 VAL n 
2 379 PHE n 
2 380 THR n 
2 381 CYS n 
2 382 VAL n 
2 383 MET n 
2 384 THR n 
2 385 LEU n 
2 386 LEU n 
2 387 TYR n 
2 388 ALA n 
2 389 PHE n 
2 390 SER n 
2 391 LYS n 
2 392 ASP n 
2 393 ILE n 
2 394 PHE n 
2 395 SER n 
2 396 VAL n 
2 397 ILE n 
2 398 ASN n 
2 399 PHE n 
2 400 PHE n 
2 401 SER n 
2 402 PHE n 
2 403 PHE n 
2 404 ASN n 
2 405 TRP n 
2 406 LEU n 
2 407 CYS n 
2 408 VAL n 
2 409 ALA n 
2 410 LEU n 
2 411 ALA n 
2 412 ILE n 
2 413 ILE n 
2 414 GLY n 
2 415 MET n 
2 416 ILE n 
2 417 TRP n 
2 418 LEU n 
2 419 ARG n 
2 420 HIS n 
2 421 ARG n 
2 422 LYS n 
2 423 PRO n 
2 424 GLU n 
2 425 LEU n 
2 426 GLU n 
2 427 ARG n 
2 428 PRO n 
2 429 ILE n 
2 430 LYS n 
2 431 VAL n 
2 432 ASN n 
2 433 LEU n 
2 434 ALA n 
2 435 LEU n 
2 436 PRO n 
2 437 VAL n 
2 438 PHE n 
2 439 PHE n 
2 440 ILE n 
2 441 LEU n 
2 442 ALA n 
2 443 CYS n 
2 444 LEU n 
2 445 PHE n 
2 446 LEU n 
2 447 ILE n 
2 448 ALA n 
2 449 VAL n 
2 450 SER n 
2 451 PHE n 
2 452 TRP n 
2 453 LYS n 
2 454 THR n 
2 455 PRO n 
2 456 VAL n 
2 457 GLU n 
2 458 CYS n 
2 459 GLY n 
2 460 ILE n 
2 461 GLY n 
2 462 PHE n 
2 463 THR n 
2 464 ILE n 
2 465 ILE n 
2 466 LEU n 
2 467 SER n 
2 468 GLY n 
2 469 LEU n 
2 470 PRO n 
2 471 VAL n 
2 472 TYR n 
2 473 PHE n 
2 474 PHE n 
2 475 GLY n 
2 476 VAL n 
2 477 TRP n 
2 478 TRP n 
2 479 LYS n 
2 480 ASN n 
2 481 LYS n 
2 482 PRO n 
2 483 LYS n 
2 484 TRP n 
2 485 LEU n 
2 486 LEU n 
2 487 GLN n 
2 488 GLY n 
2 489 ILE n 
2 490 PHE n 
2 491 SER n 
2 492 THR n 
2 493 THR n 
2 494 VAL n 
2 495 LEU n 
2 496 CYS n 
2 497 GLN n 
2 498 LYS n 
2 499 LEU n 
2 500 MET n 
2 501 GLN n 
2 502 VAL n 
2 503 VAL n 
2 504 PRO n 
2 505 GLN n 
2 506 GLU n 
2 507 THR n 
2 508 ASP n 
2 509 TYR n 
2 510 LYS n 
2 511 ASP n 
2 512 ASP n 
2 513 ASP n 
2 514 ASP n 
2 515 LYS n 
3 1   ASP n 
3 2   ILE n 
3 3   VAL n 
3 4   LEU n 
3 5   THR n 
3 6   GLN n 
3 7   SER n 
3 8   PRO n 
3 9   SER n 
3 10  SER n 
3 11  LEU n 
3 12  ALA n 
3 13  MET n 
3 14  SER n 
3 15  VAL n 
3 16  GLY n 
3 17  GLN n 
3 18  LYS n 
3 19  VAL n 
3 20  THR n 
3 21  MET n 
3 22  ASN n 
3 23  CYS n 
3 24  LYS n 
3 25  SER n 
3 26  SER n 
3 27  GLN n 
3 28  SER n 
3 29  LEU n 
3 30  LEU n 
3 31  ASN n 
3 32  ASN n 
3 33  ASN n 
3 34  ASN n 
3 35  GLN n 
3 36  LYS n 
3 37  ASN n 
3 38  TYR n 
3 39  LEU n 
3 40  ALA n 
3 41  TRP n 
3 42  TYR n 
3 43  GLN n 
3 44  GLN n 
3 45  LYS n 
3 46  PRO n 
3 47  GLY n 
3 48  GLN n 
3 49  SER n 
3 50  PRO n 
3 51  LYS n 
3 52  LEU n 
3 53  LEU n 
3 54  VAL n 
3 55  TYR n 
3 56  PHE n 
3 57  THR n 
3 58  SER n 
3 59  THR n 
3 60  ARG n 
3 61  GLU n 
3 62  SER n 
3 63  GLY n 
3 64  VAL n 
3 65  PRO n 
3 66  ASP n 
3 67  ARG n 
3 68  PHE n 
3 69  ILE n 
3 70  GLY n 
3 71  SER n 
3 72  GLY n 
3 73  SER n 
3 74  GLY n 
3 75  THR n 
3 76  ASP n 
3 77  PHE n 
3 78  THR n 
3 79  LEU n 
3 80  THR n 
3 81  ILE n 
3 82  SER n 
3 83  SER n 
3 84  VAL n 
3 85  GLN n 
3 86  ALA n 
3 87  GLU n 
3 88  ASP n 
3 89  LEU n 
3 90  ALA n 
3 91  LEU n 
3 92  TYR n 
3 93  TYR n 
3 94  CYS n 
3 95  GLN n 
3 96  GLN n 
3 97  HIS n 
3 98  TYR n 
3 99  THR n 
3 100 ILE n 
3 101 PRO n 
3 102 PRO n 
3 103 THR n 
3 104 PHE n 
3 105 GLY n 
3 106 GLY n 
3 107 GLY n 
3 108 THR n 
3 109 LYS n 
3 110 LEU n 
3 111 GLU n 
3 112 ILE n 
3 113 LYS n 
3 114 ARG n 
3 115 ALA n 
3 116 ASP n 
3 117 ALA n 
3 118 ALA n 
3 119 PRO n 
3 120 THR n 
3 121 VAL n 
3 122 SER n 
3 123 ILE n 
3 124 PHE n 
3 125 PRO n 
3 126 PRO n 
3 127 SER n 
3 128 SER n 
3 129 GLU n 
3 130 GLN n 
3 131 LEU n 
3 132 THR n 
3 133 SER n 
3 134 GLY n 
3 135 GLY n 
3 136 ALA n 
3 137 SER n 
3 138 VAL n 
3 139 VAL n 
3 140 CYS n 
3 141 PHE n 
3 142 LEU n 
3 143 ASN n 
3 144 ASN n 
3 145 PHE n 
3 146 TYR n 
3 147 PRO n 
3 148 LYS n 
3 149 ASP n 
3 150 ILE n 
3 151 ASN n 
3 152 VAL n 
3 153 LYS n 
3 154 TRP n 
3 155 LYS n 
3 156 ILE n 
3 157 ASP n 
3 158 GLY n 
3 159 SER n 
3 160 GLU n 
3 161 ARG n 
3 162 GLN n 
3 163 ASN n 
3 164 GLY n 
3 165 VAL n 
3 166 LEU n 
3 167 ASN n 
3 168 SER n 
3 169 TRP n 
3 170 THR n 
3 171 ASP n 
3 172 GLN n 
3 173 ASP n 
3 174 SER n 
3 175 LYS n 
3 176 ASP n 
3 177 SER n 
3 178 THR n 
3 179 TYR n 
3 180 SER n 
3 181 MET n 
3 182 SER n 
3 183 SER n 
3 184 THR n 
3 185 LEU n 
3 186 THR n 
3 187 LEU n 
3 188 THR n 
3 189 LYS n 
3 190 ASP n 
3 191 GLU n 
3 192 TYR n 
3 193 GLU n 
3 194 ARG n 
3 195 HIS n 
3 196 ASN n 
3 197 SER n 
3 198 TYR n 
3 199 THR n 
3 200 CYS n 
3 201 GLU n 
3 202 ALA n 
3 203 THR n 
3 204 HIS n 
3 205 LYS n 
3 206 THR n 
3 207 SER n 
3 208 THR n 
3 209 SER n 
3 210 PRO n 
3 211 ILE n 
3 212 VAL n 
3 213 LYS n 
3 214 SER n 
3 215 PHE n 
3 216 ASN n 
3 217 ARG n 
3 218 ASN n 
3 219 GLU n 
3 220 CYS n 
4 1   GLU n 
4 2   VAL n 
4 3   GLN n 
4 4   LEU n 
4 5   GLN n 
4 6   GLN n 
4 7   SER n 
4 8   GLY n 
4 9   ALA n 
4 10  GLU n 
4 11  LEU n 
4 12  VAL n 
4 13  LYS n 
4 14  PRO n 
4 15  GLY n 
4 16  ALA n 
4 17  SER n 
4 18  VAL n 
4 19  ASN n 
4 20  LEU n 
4 21  SER n 
4 22  CYS n 
4 23  LYS n 
4 24  ALA n 
4 25  SER n 
4 26  GLY n 
4 27  TYR n 
4 28  THR n 
4 29  PHE n 
4 30  THR n 
4 31  ASN n 
4 32  TYR n 
4 33  TRP n 
4 34  MET n 
4 35  HIS n 
4 36  TRP n 
4 37  VAL n 
4 38  ARG n 
4 39  LEU n 
4 40  ARG n 
4 41  PRO n 
4 42  GLY n 
4 43  GLN n 
4 44  GLY n 
4 45  LEU n 
4 46  GLU n 
4 47  TRP n 
4 48  ILE n 
4 49  GLY n 
4 50  GLU n 
4 51  ILE n 
4 52  ASP n 
4 53  PRO n 
4 54  SER n 
4 55  ASP n 
4 56  SER n 
4 57  TYR n 
4 58  SER n 
4 59  TYR n 
4 60  TYR n 
4 61  SER n 
4 62  GLN n 
4 63  ASN n 
4 64  PHE n 
4 65  LYS n 
4 66  GLY n 
4 67  LYS n 
4 68  ALA n 
4 69  THR n 
4 70  LEU n 
4 71  THR n 
4 72  VAL n 
4 73  ASP n 
4 74  GLN n 
4 75  SER n 
4 76  SER n 
4 77  ASN n 
4 78  THR n 
4 79  ALA n 
4 80  TYR n 
4 81  LEU n 
4 82  GLN n 
4 83  LEU n 
4 84  THR n 
4 85  SER n 
4 86  LEU n 
4 87  THR n 
4 88  SER n 
4 89  GLU n 
4 90  ASP n 
4 91  SER n 
4 92  ALA n 
4 93  VAL n 
4 94  TYR n 
4 95  TYR n 
4 96  CYS n 
4 97  ALA n 
4 98  ARG n 
4 99  GLY n 
4 100 ARG n 
4 101 GLN n 
4 102 THR n 
4 103 TYR n 
4 104 TYR n 
4 105 PRO n 
4 106 TRP n 
4 107 PHE n 
4 108 PRO n 
4 109 TYR n 
4 110 TRP n 
4 111 GLY n 
4 112 GLN n 
4 113 GLY n 
4 114 THR n 
4 115 LEU n 
4 116 VAL n 
4 117 THR n 
4 118 VAL n 
4 119 SER n 
4 120 ALA n 
4 121 ALA n 
4 122 LYS n 
4 123 THR n 
4 124 THR n 
4 125 PRO n 
4 126 PRO n 
4 127 SER n 
4 128 ASP n 
4 129 TYR n 
4 130 PRO n 
4 131 LEU n 
4 132 ALA n 
4 133 PRO n 
4 134 GLY n 
4 135 SER n 
4 136 ALA n 
4 137 ALA n 
4 138 GLN n 
4 139 THR n 
4 140 ASN n 
4 141 SER n 
4 142 MET n 
4 143 VAL n 
4 144 THR n 
4 145 LEU n 
4 146 GLY n 
4 147 CYS n 
4 148 LEU n 
4 149 VAL n 
4 150 LYS n 
4 151 GLY n 
4 152 TYR n 
4 153 PHE n 
4 154 PRO n 
4 155 GLU n 
4 156 PRO n 
4 157 VAL n 
4 158 THR n 
4 159 VAL n 
4 160 THR n 
4 161 TRP n 
4 162 ASN n 
4 163 SER n 
4 164 GLY n 
4 165 SER n 
4 166 LEU n 
4 167 SER n 
4 168 SER n 
4 169 GLY n 
4 170 VAL n 
4 171 HIS n 
4 172 THR n 
4 173 PHE n 
4 174 PRO n 
4 175 ALA n 
4 176 VAL n 
4 177 LEU n 
4 178 GLN n 
4 179 SER n 
4 180 ASP n 
4 181 LEU n 
4 182 TYR n 
4 183 THR n 
4 184 LEU n 
4 185 SER n 
4 186 SER n 
4 187 SER n 
4 188 VAL n 
4 189 THR n 
4 190 VAL n 
4 191 PRO n 
4 192 SER n 
4 193 SER n 
4 194 THR n 
4 195 TRP n 
4 196 PRO n 
4 197 SER n 
4 198 GLU n 
4 199 THR n 
4 200 VAL n 
4 201 THR n 
4 202 CYS n 
4 203 ASN n 
4 204 VAL n 
4 205 ALA n 
4 206 HIS n 
4 207 PRO n 
4 208 ALA n 
4 209 SER n 
4 210 SER n 
4 211 THR n 
4 212 LYS n 
4 213 VAL n 
4 214 ASP n 
4 215 LYS n 
4 216 LYS n 
4 217 ILE n 
4 218 VAL n 
4 219 PRO n 
4 220 ARG n 
4 221 ASP n 
4 222 CYS n 
4 223 GLY n 
4 224 CYS n 
4 225 LYS n 
4 226 PRO n 
4 227 CYS n 
4 228 ILE n 
4 229 CYS n 
4 230 THR n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 631 human ? 'SLC3A2, MDU1'                ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 515 human ? 'SLC7A5, CD98LC, LAT1, MPE16' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_entity_src_nat.entity_id 
_entity_src_nat.pdbx_src_id 
_entity_src_nat.pdbx_alt_source_flag 
_entity_src_nat.pdbx_beg_seq_num 
_entity_src_nat.pdbx_end_seq_num 
_entity_src_nat.common_name 
_entity_src_nat.pdbx_organism_scientific 
_entity_src_nat.pdbx_ncbi_taxonomy_id 
_entity_src_nat.genus 
_entity_src_nat.species 
_entity_src_nat.strain 
_entity_src_nat.tissue 
_entity_src_nat.tissue_fraction 
_entity_src_nat.pdbx_secretion 
_entity_src_nat.pdbx_fragment 
_entity_src_nat.pdbx_variant 
_entity_src_nat.pdbx_cell_line 
_entity_src_nat.pdbx_atcc 
_entity_src_nat.pdbx_cellular_location 
_entity_src_nat.pdbx_organ 
_entity_src_nat.pdbx_organelle 
_entity_src_nat.pdbx_cell 
_entity_src_nat.pdbx_plasmid_name 
_entity_src_nat.pdbx_plasmid_details 
_entity_src_nat.details 
3 1 sample 1 220 ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 1 230 ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'          y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'          y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking'          y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'          y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'            y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'          y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'          y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'          y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'          y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'          y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'          y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'          y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'          y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'          y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'          y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'          y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   0   ?   ?   ?   A . n 
A 1 2   SER 2   1   ?   ?   ?   A . n 
A 1 3   GLU 3   2   ?   ?   ?   A . n 
A 1 4   LEU 4   3   ?   ?   ?   A . n 
A 1 5   GLN 5   4   ?   ?   ?   A . n 
A 1 6   PRO 6   5   ?   ?   ?   A . n 
A 1 7   PRO 7   6   ?   ?   ?   A . n 
A 1 8   GLU 8   7   ?   ?   ?   A . n 
A 1 9   ALA 9   8   ?   ?   ?   A . n 
A 1 10  SER 10  9   ?   ?   ?   A . n 
A 1 11  ILE 11  10  ?   ?   ?   A . n 
A 1 12  ALA 12  11  ?   ?   ?   A . n 
A 1 13  VAL 13  12  ?   ?   ?   A . n 
A 1 14  VAL 14  13  ?   ?   ?   A . n 
A 1 15  SER 15  14  ?   ?   ?   A . n 
A 1 16  ILE 16  15  ?   ?   ?   A . n 
A 1 17  PRO 17  16  ?   ?   ?   A . n 
A 1 18  ARG 18  17  ?   ?   ?   A . n 
A 1 19  GLN 19  18  ?   ?   ?   A . n 
A 1 20  LEU 20  19  ?   ?   ?   A . n 
A 1 21  PRO 21  20  ?   ?   ?   A . n 
A 1 22  GLY 22  21  ?   ?   ?   A . n 
A 1 23  SER 23  22  ?   ?   ?   A . n 
A 1 24  HIS 24  23  ?   ?   ?   A . n 
A 1 25  SER 25  24  ?   ?   ?   A . n 
A 1 26  GLU 26  25  ?   ?   ?   A . n 
A 1 27  ALA 27  26  ?   ?   ?   A . n 
A 1 28  GLY 28  27  ?   ?   ?   A . n 
A 1 29  VAL 29  28  ?   ?   ?   A . n 
A 1 30  GLN 30  29  ?   ?   ?   A . n 
A 1 31  GLY 31  30  ?   ?   ?   A . n 
A 1 32  LEU 32  31  ?   ?   ?   A . n 
A 1 33  SER 33  32  ?   ?   ?   A . n 
A 1 34  ALA 34  33  ?   ?   ?   A . n 
A 1 35  GLY 35  34  ?   ?   ?   A . n 
A 1 36  ASP 36  35  ?   ?   ?   A . n 
A 1 37  ASP 37  36  ?   ?   ?   A . n 
A 1 38  SER 38  37  ?   ?   ?   A . n 
A 1 39  GLU 39  38  ?   ?   ?   A . n 
A 1 40  LEU 40  39  ?   ?   ?   A . n 
A 1 41  GLY 41  40  ?   ?   ?   A . n 
A 1 42  SER 42  41  ?   ?   ?   A . n 
A 1 43  HIS 43  42  ?   ?   ?   A . n 
A 1 44  CYS 44  43  ?   ?   ?   A . n 
A 1 45  VAL 45  44  ?   ?   ?   A . n 
A 1 46  ALA 46  45  ?   ?   ?   A . n 
A 1 47  GLN 47  46  ?   ?   ?   A . n 
A 1 48  THR 48  47  ?   ?   ?   A . n 
A 1 49  GLY 49  48  ?   ?   ?   A . n 
A 1 50  LEU 50  49  ?   ?   ?   A . n 
A 1 51  GLU 51  50  ?   ?   ?   A . n 
A 1 52  LEU 52  51  ?   ?   ?   A . n 
A 1 53  LEU 53  52  ?   ?   ?   A . n 
A 1 54  ALA 54  53  ?   ?   ?   A . n 
A 1 55  SER 55  54  ?   ?   ?   A . n 
A 1 56  GLY 56  55  ?   ?   ?   A . n 
A 1 57  ASP 57  56  ?   ?   ?   A . n 
A 1 58  PRO 58  57  ?   ?   ?   A . n 
A 1 59  LEU 59  58  ?   ?   ?   A . n 
A 1 60  PRO 60  59  ?   ?   ?   A . n 
A 1 61  SER 61  60  ?   ?   ?   A . n 
A 1 62  ALA 62  61  ?   ?   ?   A . n 
A 1 63  SER 63  62  ?   ?   ?   A . n 
A 1 64  GLN 64  63  ?   ?   ?   A . n 
A 1 65  ASN 65  64  ?   ?   ?   A . n 
A 1 66  ALA 66  65  ?   ?   ?   A . n 
A 1 67  GLU 67  66  ?   ?   ?   A . n 
A 1 68  MET 68  67  ?   ?   ?   A . n 
A 1 69  ILE 69  68  ?   ?   ?   A . n 
A 1 70  GLU 70  69  ?   ?   ?   A . n 
A 1 71  THR 71  70  ?   ?   ?   A . n 
A 1 72  GLY 72  71  ?   ?   ?   A . n 
A 1 73  SER 73  72  ?   ?   ?   A . n 
A 1 74  ASP 74  73  ?   ?   ?   A . n 
A 1 75  CYS 75  74  ?   ?   ?   A . n 
A 1 76  VAL 76  75  ?   ?   ?   A . n 
A 1 77  THR 77  76  ?   ?   ?   A . n 
A 1 78  GLN 78  77  ?   ?   ?   A . n 
A 1 79  ALA 79  78  ?   ?   ?   A . n 
A 1 80  GLY 80  79  ?   ?   ?   A . n 
A 1 81  LEU 81  80  ?   ?   ?   A . n 
A 1 82  GLN 82  81  ?   ?   ?   A . n 
A 1 83  LEU 83  82  ?   ?   ?   A . n 
A 1 84  LEU 84  83  ?   ?   ?   A . n 
A 1 85  ALA 85  84  ?   ?   ?   A . n 
A 1 86  SER 86  85  ?   ?   ?   A . n 
A 1 87  SER 87  86  ?   ?   ?   A . n 
A 1 88  ASP 88  87  ?   ?   ?   A . n 
A 1 89  PRO 89  88  ?   ?   ?   A . n 
A 1 90  PRO 90  89  ?   ?   ?   A . n 
A 1 91  ALA 91  90  ?   ?   ?   A . n 
A 1 92  LEU 92  91  ?   ?   ?   A . n 
A 1 93  ALA 93  92  ?   ?   ?   A . n 
A 1 94  SER 94  93  ?   ?   ?   A . n 
A 1 95  LYS 95  94  ?   ?   ?   A . n 
A 1 96  ASN 96  95  ?   ?   ?   A . n 
A 1 97  ALA 97  96  ?   ?   ?   A . n 
A 1 98  GLU 98  97  ?   ?   ?   A . n 
A 1 99  VAL 99  98  ?   ?   ?   A . n 
A 1 100 THR 100 99  ?   ?   ?   A . n 
A 1 101 GLY 101 100 ?   ?   ?   A . n 
A 1 102 THR 102 101 ?   ?   ?   A . n 
A 1 103 MET 103 102 ?   ?   ?   A . n 
A 1 104 SER 104 103 ?   ?   ?   A . n 
A 1 105 GLN 105 104 ?   ?   ?   A . n 
A 1 106 ASP 106 105 ?   ?   ?   A . n 
A 1 107 THR 107 106 ?   ?   ?   A . n 
A 1 108 GLU 108 107 ?   ?   ?   A . n 
A 1 109 VAL 109 108 ?   ?   ?   A . n 
A 1 110 ASP 110 109 ?   ?   ?   A . n 
A 1 111 MET 111 110 ?   ?   ?   A . n 
A 1 112 LYS 112 111 ?   ?   ?   A . n 
A 1 113 GLU 113 112 ?   ?   ?   A . n 
A 1 114 VAL 114 113 ?   ?   ?   A . n 
A 1 115 GLU 115 114 ?   ?   ?   A . n 
A 1 116 LEU 116 115 ?   ?   ?   A . n 
A 1 117 ASN 117 116 ?   ?   ?   A . n 
A 1 118 GLU 118 117 ?   ?   ?   A . n 
A 1 119 LEU 119 118 ?   ?   ?   A . n 
A 1 120 GLU 120 119 ?   ?   ?   A . n 
A 1 121 PRO 121 120 ?   ?   ?   A . n 
A 1 122 GLU 122 121 ?   ?   ?   A . n 
A 1 123 LYS 123 122 ?   ?   ?   A . n 
A 1 124 GLN 124 123 ?   ?   ?   A . n 
A 1 125 PRO 125 124 ?   ?   ?   A . n 
A 1 126 MET 126 125 ?   ?   ?   A . n 
A 1 127 ASN 127 126 ?   ?   ?   A . n 
A 1 128 ALA 128 127 ?   ?   ?   A . n 
A 1 129 ALA 129 128 ?   ?   ?   A . n 
A 1 130 SER 130 129 ?   ?   ?   A . n 
A 1 131 GLY 131 130 ?   ?   ?   A . n 
A 1 132 ALA 132 131 ?   ?   ?   A . n 
A 1 133 ALA 133 132 ?   ?   ?   A . n 
A 1 134 MET 134 133 ?   ?   ?   A . n 
A 1 135 SER 135 134 ?   ?   ?   A . n 
A 1 136 LEU 136 135 ?   ?   ?   A . n 
A 1 137 ALA 137 136 ?   ?   ?   A . n 
A 1 138 GLY 138 137 ?   ?   ?   A . n 
A 1 139 ALA 139 138 ?   ?   ?   A . n 
A 1 140 GLU 140 139 ?   ?   ?   A . n 
A 1 141 LYS 141 140 ?   ?   ?   A . n 
A 1 142 ASN 142 141 ?   ?   ?   A . n 
A 1 143 GLY 143 142 ?   ?   ?   A . n 
A 1 144 LEU 144 143 ?   ?   ?   A . n 
A 1 145 VAL 145 144 ?   ?   ?   A . n 
A 1 146 LYS 146 145 ?   ?   ?   A . n 
A 1 147 ILE 147 146 ?   ?   ?   A . n 
A 1 148 LYS 148 147 ?   ?   ?   A . n 
A 1 149 VAL 149 148 ?   ?   ?   A . n 
A 1 150 ALA 150 149 ?   ?   ?   A . n 
A 1 151 GLU 151 150 ?   ?   ?   A . n 
A 1 152 ASP 152 151 ?   ?   ?   A . n 
A 1 153 GLU 153 152 ?   ?   ?   A . n 
A 1 154 ALA 154 153 ?   ?   ?   A . n 
A 1 155 GLU 155 154 ?   ?   ?   A . n 
A 1 156 ALA 156 155 ?   ?   ?   A . n 
A 1 157 ALA 157 156 ?   ?   ?   A . n 
A 1 158 ALA 158 157 ?   ?   ?   A . n 
A 1 159 ALA 159 158 ?   ?   ?   A . n 
A 1 160 ALA 160 159 ?   ?   ?   A . n 
A 1 161 LYS 161 160 ?   ?   ?   A . n 
A 1 162 PHE 162 161 ?   ?   ?   A . n 
A 1 163 THR 163 162 162 THR THR A . n 
A 1 164 GLY 164 163 163 GLY GLY A . n 
A 1 165 LEU 165 164 164 LEU LEU A . n 
A 1 166 SER 166 165 165 SER SER A . n 
A 1 167 LYS 167 166 166 LYS LYS A . n 
A 1 168 GLU 168 167 167 GLU GLU A . n 
A 1 169 GLU 169 168 168 GLU GLU A . n 
A 1 170 LEU 170 169 169 LEU LEU A . n 
A 1 171 LEU 171 170 170 LEU LEU A . n 
A 1 172 LYS 172 171 171 LYS LYS A . n 
A 1 173 VAL 173 172 172 VAL VAL A . n 
A 1 174 ALA 174 173 173 ALA ALA A . n 
A 1 175 GLY 175 174 174 GLY GLY A . n 
A 1 176 SER 176 175 175 SER SER A . n 
A 1 177 PRO 177 176 176 PRO PRO A . n 
A 1 178 GLY 178 177 177 GLY GLY A . n 
A 1 179 TRP 179 178 178 TRP TRP A . n 
A 1 180 VAL 180 179 179 VAL VAL A . n 
A 1 181 ARG 181 180 180 ARG ARG A . n 
A 1 182 THR 182 181 181 THR THR A . n 
A 1 183 ARG 183 182 182 ARG ARG A . n 
A 1 184 TRP 184 183 183 TRP TRP A . n 
A 1 185 ALA 185 184 184 ALA ALA A . n 
A 1 186 LEU 186 185 185 LEU LEU A . n 
A 1 187 LEU 187 186 186 LEU LEU A . n 
A 1 188 LEU 188 187 187 LEU LEU A . n 
A 1 189 LEU 189 188 188 LEU LEU A . n 
A 1 190 PHE 190 189 189 PHE PHE A . n 
A 1 191 TRP 191 190 190 TRP TRP A . n 
A 1 192 LEU 192 191 191 LEU LEU A . n 
A 1 193 GLY 193 192 192 GLY GLY A . n 
A 1 194 TRP 194 193 193 TRP TRP A . n 
A 1 195 LEU 195 194 194 LEU LEU A . n 
A 1 196 GLY 196 195 195 GLY GLY A . n 
A 1 197 MET 197 196 196 MET MET A . n 
A 1 198 LEU 198 197 197 LEU LEU A . n 
A 1 199 ALA 199 198 198 ALA ALA A . n 
A 1 200 GLY 200 199 199 GLY GLY A . n 
A 1 201 ALA 201 200 200 ALA ALA A . n 
A 1 202 VAL 202 201 201 VAL VAL A . n 
A 1 203 VAL 203 202 202 VAL VAL A . n 
A 1 204 ILE 204 203 203 ILE ILE A . n 
A 1 205 ILE 205 204 204 ILE ILE A . n 
A 1 206 VAL 206 205 205 VAL VAL A . n 
A 1 207 ARG 207 206 206 ARG ARG A . n 
A 1 208 ALA 208 207 207 ALA ALA A . n 
A 1 209 PRO 209 208 208 PRO PRO A . n 
A 1 210 ARG 210 209 209 ARG ARG A . n 
A 1 211 CYS 211 210 210 CYS CYS A . n 
A 1 212 ARG 212 211 211 ARG ARG A . n 
A 1 213 GLU 213 212 212 GLU GLU A . n 
A 1 214 LEU 214 213 213 LEU LEU A . n 
A 1 215 PRO 215 214 214 PRO PRO A . n 
A 1 216 ALA 216 215 215 ALA ALA A . n 
A 1 217 GLN 217 216 216 GLN GLN A . n 
A 1 218 LYS 218 217 217 LYS LYS A . n 
A 1 219 TRP 219 218 218 TRP TRP A . n 
A 1 220 TRP 220 219 219 TRP TRP A . n 
A 1 221 HIS 221 220 220 HIS HIS A . n 
A 1 222 THR 222 221 221 THR THR A . n 
A 1 223 GLY 223 222 222 GLY GLY A . n 
A 1 224 ALA 224 223 223 ALA ALA A . n 
A 1 225 LEU 225 224 224 LEU LEU A . n 
A 1 226 TYR 226 225 225 TYR TYR A . n 
A 1 227 ARG 227 226 226 ARG ARG A . n 
A 1 228 ILE 228 227 227 ILE ILE A . n 
A 1 229 GLY 229 228 228 GLY GLY A . n 
A 1 230 ASP 230 229 229 ASP ASP A . n 
A 1 231 LEU 231 230 230 LEU LEU A . n 
A 1 232 GLN 232 231 231 GLN GLN A . n 
A 1 233 ALA 233 232 232 ALA ALA A . n 
A 1 234 PHE 234 233 233 PHE PHE A . n 
A 1 235 GLN 235 234 234 GLN GLN A . n 
A 1 236 GLY 236 235 235 GLY GLY A . n 
A 1 237 HIS 237 236 236 HIS HIS A . n 
A 1 238 GLY 238 237 237 GLY GLY A . n 
A 1 239 ALA 239 238 238 ALA ALA A . n 
A 1 240 GLY 240 239 239 GLY GLY A . n 
A 1 241 ASN 241 240 240 ASN ASN A . n 
A 1 242 LEU 242 241 241 LEU LEU A . n 
A 1 243 ALA 243 242 242 ALA ALA A . n 
A 1 244 GLY 244 243 243 GLY GLY A . n 
A 1 245 LEU 245 244 244 LEU LEU A . n 
A 1 246 LYS 246 245 245 LYS LYS A . n 
A 1 247 GLY 247 246 246 GLY GLY A . n 
A 1 248 ARG 248 247 247 ARG ARG A . n 
A 1 249 LEU 249 248 248 LEU LEU A . n 
A 1 250 ASP 250 249 249 ASP ASP A . n 
A 1 251 TYR 251 250 250 TYR TYR A . n 
A 1 252 LEU 252 251 251 LEU LEU A . n 
A 1 253 SER 253 252 252 SER SER A . n 
A 1 254 SER 254 253 253 SER SER A . n 
A 1 255 LEU 255 254 254 LEU LEU A . n 
A 1 256 LYS 256 255 255 LYS LYS A . n 
A 1 257 VAL 257 256 256 VAL VAL A . n 
A 1 258 LYS 258 257 257 LYS LYS A . n 
A 1 259 GLY 259 258 258 GLY GLY A . n 
A 1 260 LEU 260 259 259 LEU LEU A . n 
A 1 261 VAL 261 260 260 VAL VAL A . n 
A 1 262 LEU 262 261 261 LEU LEU A . n 
A 1 263 GLY 263 262 262 GLY GLY A . n 
A 1 264 PRO 264 263 263 PRO PRO A . n 
A 1 265 ILE 265 264 264 ILE ILE A . n 
A 1 266 HIS 266 265 265 HIS HIS A . n 
A 1 267 LYS 267 266 266 LYS LYS A . n 
A 1 268 ASN 268 267 267 ASN ASN A . n 
A 1 269 GLN 269 268 268 GLN GLN A . n 
A 1 270 LYS 270 269 269 LYS LYS A . n 
A 1 271 ASP 271 270 270 ASP ASP A . n 
A 1 272 ASP 272 271 271 ASP ASP A . n 
A 1 273 VAL 273 272 272 VAL VAL A . n 
A 1 274 ALA 274 273 273 ALA ALA A . n 
A 1 275 GLN 275 274 274 GLN GLN A . n 
A 1 276 THR 276 275 275 THR THR A . n 
A 1 277 ASP 277 276 276 ASP ASP A . n 
A 1 278 LEU 278 277 277 LEU LEU A . n 
A 1 279 LEU 279 278 278 LEU LEU A . n 
A 1 280 GLN 280 279 279 GLN GLN A . n 
A 1 281 ILE 281 280 280 ILE ILE A . n 
A 1 282 ASP 282 281 281 ASP ASP A . n 
A 1 283 PRO 283 282 282 PRO PRO A . n 
A 1 284 ASN 284 283 283 ASN ASN A . n 
A 1 285 PHE 285 284 284 PHE PHE A . n 
A 1 286 GLY 286 285 285 GLY GLY A . n 
A 1 287 SER 287 286 286 SER SER A . n 
A 1 288 LYS 288 287 287 LYS LYS A . n 
A 1 289 GLU 289 288 288 GLU GLU A . n 
A 1 290 ASP 290 289 289 ASP ASP A . n 
A 1 291 PHE 291 290 290 PHE PHE A . n 
A 1 292 ASP 292 291 291 ASP ASP A . n 
A 1 293 SER 293 292 292 SER SER A . n 
A 1 294 LEU 294 293 293 LEU LEU A . n 
A 1 295 LEU 295 294 294 LEU LEU A . n 
A 1 296 GLN 296 295 295 GLN GLN A . n 
A 1 297 SER 297 296 296 SER SER A . n 
A 1 298 ALA 298 297 297 ALA ALA A . n 
A 1 299 LYS 299 298 298 LYS LYS A . n 
A 1 300 LYS 300 299 299 LYS LYS A . n 
A 1 301 LYS 301 300 300 LYS LYS A . n 
A 1 302 SER 302 301 301 SER SER A . n 
A 1 303 ILE 303 302 302 ILE ILE A . n 
A 1 304 ARG 304 303 303 ARG ARG A . n 
A 1 305 VAL 305 304 304 VAL VAL A . n 
A 1 306 ILE 306 305 305 ILE ILE A . n 
A 1 307 LEU 307 306 306 LEU LEU A . n 
A 1 308 ASP 308 307 307 ASP ASP A . n 
A 1 309 LEU 309 308 308 LEU LEU A . n 
A 1 310 THR 310 309 309 THR THR A . n 
A 1 311 PRO 311 310 310 PRO PRO A . n 
A 1 312 ASN 312 311 311 ASN ASN A . n 
A 1 313 TYR 313 312 312 TYR TYR A . n 
A 1 314 ARG 314 313 313 ARG ARG A . n 
A 1 315 GLY 315 314 314 GLY GLY A . n 
A 1 316 GLU 316 315 315 GLU GLU A . n 
A 1 317 ASN 317 316 316 ASN ASN A . n 
A 1 318 SER 318 317 317 SER SER A . n 
A 1 319 TRP 319 318 318 TRP TRP A . n 
A 1 320 PHE 320 319 319 PHE PHE A . n 
A 1 321 SER 321 320 320 SER SER A . n 
A 1 322 THR 322 321 321 THR THR A . n 
A 1 323 GLN 323 322 322 GLN GLN A . n 
A 1 324 VAL 324 323 323 VAL VAL A . n 
A 1 325 ASP 325 324 324 ASP ASP A . n 
A 1 326 THR 326 325 325 THR THR A . n 
A 1 327 VAL 327 326 326 VAL VAL A . n 
A 1 328 ALA 328 327 327 ALA ALA A . n 
A 1 329 THR 329 328 328 THR THR A . n 
A 1 330 LYS 330 329 329 LYS LYS A . n 
A 1 331 VAL 331 330 330 VAL VAL A . n 
A 1 332 LYS 332 331 331 LYS LYS A . n 
A 1 333 ASP 333 332 332 ASP ASP A . n 
A 1 334 ALA 334 333 333 ALA ALA A . n 
A 1 335 LEU 335 334 334 LEU LEU A . n 
A 1 336 GLU 336 335 335 GLU GLU A . n 
A 1 337 PHE 337 336 336 PHE PHE A . n 
A 1 338 TRP 338 337 337 TRP TRP A . n 
A 1 339 LEU 339 338 338 LEU LEU A . n 
A 1 340 GLN 340 339 339 GLN GLN A . n 
A 1 341 ALA 341 340 340 ALA ALA A . n 
A 1 342 GLY 342 341 341 GLY GLY A . n 
A 1 343 VAL 343 342 342 VAL VAL A . n 
A 1 344 ASP 344 343 343 ASP ASP A . n 
A 1 345 GLY 345 344 344 GLY GLY A . n 
A 1 346 PHE 346 345 345 PHE PHE A . n 
A 1 347 GLN 347 346 346 GLN GLN A . n 
A 1 348 VAL 348 347 347 VAL VAL A . n 
A 1 349 ARG 349 348 348 ARG ARG A . n 
A 1 350 ASP 350 349 349 ASP ASP A . n 
A 1 351 ILE 351 350 350 ILE ILE A . n 
A 1 352 GLU 352 351 351 GLU GLU A . n 
A 1 353 ASN 353 352 352 ASN ASN A . n 
A 1 354 LEU 354 353 353 LEU LEU A . n 
A 1 355 LYS 355 354 354 LYS LYS A . n 
A 1 356 ASP 356 355 355 ASP ASP A . n 
A 1 357 ALA 357 356 356 ALA ALA A . n 
A 1 358 SER 358 357 357 SER SER A . n 
A 1 359 SER 359 358 358 SER SER A . n 
A 1 360 PHE 360 359 359 PHE PHE A . n 
A 1 361 LEU 361 360 360 LEU LEU A . n 
A 1 362 ALA 362 361 361 ALA ALA A . n 
A 1 363 GLU 363 362 362 GLU GLU A . n 
A 1 364 TRP 364 363 363 TRP TRP A . n 
A 1 365 GLN 365 364 364 GLN GLN A . n 
A 1 366 ASN 366 365 365 ASN ASN A . n 
A 1 367 ILE 367 366 366 ILE ILE A . n 
A 1 368 THR 368 367 367 THR THR A . n 
A 1 369 LYS 369 368 368 LYS LYS A . n 
A 1 370 GLY 370 369 369 GLY GLY A . n 
A 1 371 PHE 371 370 370 PHE PHE A . n 
A 1 372 SER 372 371 371 SER SER A . n 
A 1 373 GLU 373 372 372 GLU GLU A . n 
A 1 374 ASP 374 373 373 ASP ASP A . n 
A 1 375 ARG 375 374 374 ARG ARG A . n 
A 1 376 LEU 376 375 375 LEU LEU A . n 
A 1 377 LEU 377 376 376 LEU LEU A . n 
A 1 378 ILE 378 377 377 ILE ILE A . n 
A 1 379 ALA 379 378 378 ALA ALA A . n 
A 1 380 GLY 380 379 379 GLY GLY A . n 
A 1 381 THR 381 380 380 THR THR A . n 
A 1 382 ASN 382 381 381 ASN ASN A . n 
A 1 383 SER 383 382 382 SER SER A . n 
A 1 384 SER 384 383 383 SER SER A . n 
A 1 385 ASP 385 384 384 ASP ASP A . n 
A 1 386 LEU 386 385 385 LEU LEU A . n 
A 1 387 GLN 387 386 386 GLN GLN A . n 
A 1 388 GLN 388 387 387 GLN GLN A . n 
A 1 389 ILE 389 388 388 ILE ILE A . n 
A 1 390 LEU 390 389 389 LEU LEU A . n 
A 1 391 SER 391 390 390 SER SER A . n 
A 1 392 LEU 392 391 391 LEU LEU A . n 
A 1 393 LEU 393 392 392 LEU LEU A . n 
A 1 394 GLU 394 393 393 GLU GLU A . n 
A 1 395 SER 395 394 394 SER SER A . n 
A 1 396 ASN 396 395 395 ASN ASN A . n 
A 1 397 LYS 397 396 396 LYS LYS A . n 
A 1 398 ASP 398 397 397 ASP ASP A . n 
A 1 399 LEU 399 398 398 LEU LEU A . n 
A 1 400 LEU 400 399 399 LEU LEU A . n 
A 1 401 LEU 401 400 400 LEU LEU A . n 
A 1 402 THR 402 401 401 THR THR A . n 
A 1 403 SER 403 402 402 SER SER A . n 
A 1 404 SER 404 403 403 SER SER A . n 
A 1 405 TYR 405 404 404 TYR TYR A . n 
A 1 406 LEU 406 405 405 LEU LEU A . n 
A 1 407 SER 407 406 406 SER SER A . n 
A 1 408 ASP 408 407 407 ASP ASP A . n 
A 1 409 SER 409 408 408 SER SER A . n 
A 1 410 GLY 410 409 409 GLY GLY A . n 
A 1 411 SER 411 410 410 SER SER A . n 
A 1 412 THR 412 411 411 THR THR A . n 
A 1 413 GLY 413 412 412 GLY GLY A . n 
A 1 414 GLU 414 413 413 GLU GLU A . n 
A 1 415 HIS 415 414 414 HIS HIS A . n 
A 1 416 THR 416 415 415 THR THR A . n 
A 1 417 LYS 417 416 416 LYS LYS A . n 
A 1 418 SER 418 417 417 SER SER A . n 
A 1 419 LEU 419 418 418 LEU LEU A . n 
A 1 420 VAL 420 419 419 VAL VAL A . n 
A 1 421 THR 421 420 420 THR THR A . n 
A 1 422 GLN 422 421 421 GLN GLN A . n 
A 1 423 TYR 423 422 422 TYR TYR A . n 
A 1 424 LEU 424 423 423 LEU LEU A . n 
A 1 425 ASN 425 424 424 ASN ASN A . n 
A 1 426 ALA 426 425 425 ALA ALA A . n 
A 1 427 THR 427 426 426 THR THR A . n 
A 1 428 GLY 428 427 427 GLY GLY A . n 
A 1 429 ASN 429 428 428 ASN ASN A . n 
A 1 430 ARG 430 429 429 ARG ARG A . n 
A 1 431 TRP 431 430 430 TRP TRP A . n 
A 1 432 CYS 432 431 431 CYS CYS A . n 
A 1 433 SER 433 432 432 SER SER A . n 
A 1 434 TRP 434 433 433 TRP TRP A . n 
A 1 435 SER 435 434 434 SER SER A . n 
A 1 436 LEU 436 435 435 LEU LEU A . n 
A 1 437 SER 437 436 436 SER SER A . n 
A 1 438 GLN 438 437 437 GLN GLN A . n 
A 1 439 ALA 439 438 438 ALA ALA A . n 
A 1 440 ARG 440 439 439 ARG ARG A . n 
A 1 441 LEU 441 440 440 LEU LEU A . n 
A 1 442 LEU 442 441 441 LEU LEU A . n 
A 1 443 THR 443 442 442 THR THR A . n 
A 1 444 SER 444 443 443 SER SER A . n 
A 1 445 PHE 445 444 444 PHE PHE A . n 
A 1 446 LEU 446 445 445 LEU LEU A . n 
A 1 447 PRO 447 446 446 PRO PRO A . n 
A 1 448 ALA 448 447 447 ALA ALA A . n 
A 1 449 GLN 449 448 448 GLN GLN A . n 
A 1 450 LEU 450 449 449 LEU LEU A . n 
A 1 451 LEU 451 450 450 LEU LEU A . n 
A 1 452 ARG 452 451 451 ARG ARG A . n 
A 1 453 LEU 453 452 452 LEU LEU A . n 
A 1 454 TYR 454 453 453 TYR TYR A . n 
A 1 455 GLN 455 454 454 GLN GLN A . n 
A 1 456 LEU 456 455 455 LEU LEU A . n 
A 1 457 MET 457 456 456 MET MET A . n 
A 1 458 LEU 458 457 457 LEU LEU A . n 
A 1 459 PHE 459 458 458 PHE PHE A . n 
A 1 460 THR 460 459 459 THR THR A . n 
A 1 461 LEU 461 460 460 LEU LEU A . n 
A 1 462 PRO 462 461 461 PRO PRO A . n 
A 1 463 GLY 463 462 462 GLY GLY A . n 
A 1 464 THR 464 463 463 THR THR A . n 
A 1 465 PRO 465 464 464 PRO PRO A . n 
A 1 466 VAL 466 465 465 VAL VAL A . n 
A 1 467 PHE 467 466 466 PHE PHE A . n 
A 1 468 SER 468 467 467 SER SER A . n 
A 1 469 TYR 469 468 468 TYR TYR A . n 
A 1 470 GLY 470 469 469 GLY GLY A . n 
A 1 471 ASP 471 470 470 ASP ASP A . n 
A 1 472 GLU 472 471 471 GLU GLU A . n 
A 1 473 ILE 473 472 472 ILE ILE A . n 
A 1 474 GLY 474 473 473 GLY GLY A . n 
A 1 475 LEU 475 474 474 LEU LEU A . n 
A 1 476 ASP 476 475 475 ASP ASP A . n 
A 1 477 ALA 477 476 476 ALA ALA A . n 
A 1 478 ALA 478 477 477 ALA ALA A . n 
A 1 479 ALA 479 478 478 ALA ALA A . n 
A 1 480 LEU 480 479 479 LEU LEU A . n 
A 1 481 PRO 481 480 480 PRO PRO A . n 
A 1 482 GLY 482 481 481 GLY GLY A . n 
A 1 483 GLN 483 482 482 GLN GLN A . n 
A 1 484 PRO 484 483 483 PRO PRO A . n 
A 1 485 MET 485 484 484 MET MET A . n 
A 1 486 GLU 486 485 485 GLU GLU A . n 
A 1 487 ALA 487 486 486 ALA ALA A . n 
A 1 488 PRO 488 487 487 PRO PRO A . n 
A 1 489 VAL 489 488 488 VAL VAL A . n 
A 1 490 MET 490 489 489 MET MET A . n 
A 1 491 LEU 491 490 490 LEU LEU A . n 
A 1 492 TRP 492 491 491 TRP TRP A . n 
A 1 493 ASP 493 492 492 ASP ASP A . n 
A 1 494 GLU 494 493 493 GLU GLU A . n 
A 1 495 SER 495 494 494 SER SER A . n 
A 1 496 SER 496 495 495 SER SER A . n 
A 1 497 PHE 497 496 496 PHE PHE A . n 
A 1 498 PRO 498 497 497 PRO PRO A . n 
A 1 499 ASP 499 498 498 ASP ASP A . n 
A 1 500 ILE 500 499 499 ILE ILE A . n 
A 1 501 PRO 501 500 500 PRO PRO A . n 
A 1 502 GLY 502 501 501 GLY GLY A . n 
A 1 503 ALA 503 502 502 ALA ALA A . n 
A 1 504 VAL 504 503 503 VAL VAL A . n 
A 1 505 SER 505 504 504 SER SER A . n 
A 1 506 ALA 506 505 505 ALA ALA A . n 
A 1 507 ASN 507 506 506 ASN ASN A . n 
A 1 508 MET 508 507 507 MET MET A . n 
A 1 509 THR 509 508 508 THR THR A . n 
A 1 510 VAL 510 509 509 VAL VAL A . n 
A 1 511 LYS 511 510 510 LYS LYS A . n 
A 1 512 GLY 512 511 511 GLY GLY A . n 
A 1 513 GLN 513 512 512 GLN GLN A . n 
A 1 514 SER 514 513 513 SER SER A . n 
A 1 515 GLU 515 514 514 GLU GLU A . n 
A 1 516 ASP 516 515 515 ASP ASP A . n 
A 1 517 PRO 517 516 516 PRO PRO A . n 
A 1 518 GLY 518 517 517 GLY GLY A . n 
A 1 519 SER 519 518 518 SER SER A . n 
A 1 520 LEU 520 519 519 LEU LEU A . n 
A 1 521 LEU 521 520 520 LEU LEU A . n 
A 1 522 SER 522 521 521 SER SER A . n 
A 1 523 LEU 523 522 522 LEU LEU A . n 
A 1 524 PHE 524 523 523 PHE PHE A . n 
A 1 525 ARG 525 524 524 ARG ARG A . n 
A 1 526 ARG 526 525 525 ARG ARG A . n 
A 1 527 LEU 527 526 526 LEU LEU A . n 
A 1 528 SER 528 527 527 SER SER A . n 
A 1 529 ASP 529 528 528 ASP ASP A . n 
A 1 530 GLN 530 529 529 GLN GLN A . n 
A 1 531 ARG 531 530 530 ARG ARG A . n 
A 1 532 SER 532 531 531 SER SER A . n 
A 1 533 LYS 533 532 532 LYS LYS A . n 
A 1 534 GLU 534 533 533 GLU GLU A . n 
A 1 535 ARG 535 534 534 ARG ARG A . n 
A 1 536 SER 536 535 535 SER SER A . n 
A 1 537 LEU 537 536 536 LEU LEU A . n 
A 1 538 LEU 538 537 537 LEU LEU A . n 
A 1 539 HIS 539 538 538 HIS HIS A . n 
A 1 540 GLY 540 539 539 GLY GLY A . n 
A 1 541 ASP 541 540 540 ASP ASP A . n 
A 1 542 PHE 542 541 541 PHE PHE A . n 
A 1 543 HIS 543 542 542 HIS HIS A . n 
A 1 544 ALA 544 543 543 ALA ALA A . n 
A 1 545 PHE 545 544 544 PHE PHE A . n 
A 1 546 SER 546 545 545 SER SER A . n 
A 1 547 ALA 547 546 546 ALA ALA A . n 
A 1 548 GLY 548 547 547 GLY GLY A . n 
A 1 549 PRO 549 548 548 PRO PRO A . n 
A 1 550 GLY 550 549 549 GLY GLY A . n 
A 1 551 LEU 551 550 550 LEU LEU A . n 
A 1 552 PHE 552 551 551 PHE PHE A . n 
A 1 553 SER 553 552 552 SER SER A . n 
A 1 554 TYR 554 553 553 TYR TYR A . n 
A 1 555 ILE 555 554 554 ILE ILE A . n 
A 1 556 ARG 556 555 555 ARG ARG A . n 
A 1 557 HIS 557 556 556 HIS HIS A . n 
A 1 558 TRP 558 557 557 TRP TRP A . n 
A 1 559 ASP 559 558 558 ASP ASP A . n 
A 1 560 GLN 560 559 559 GLN GLN A . n 
A 1 561 ASN 561 560 560 ASN ASN A . n 
A 1 562 GLU 562 561 561 GLU GLU A . n 
A 1 563 ARG 563 562 562 ARG ARG A . n 
A 1 564 PHE 564 563 563 PHE PHE A . n 
A 1 565 LEU 565 564 564 LEU LEU A . n 
A 1 566 VAL 566 565 565 VAL VAL A . n 
A 1 567 VAL 567 566 566 VAL VAL A . n 
A 1 568 LEU 568 567 567 LEU LEU A . n 
A 1 569 ASN 569 568 568 ASN ASN A . n 
A 1 570 PHE 570 569 569 PHE PHE A . n 
A 1 571 GLY 571 570 570 GLY GLY A . n 
A 1 572 ASP 572 571 571 ASP ASP A . n 
A 1 573 VAL 573 572 572 VAL VAL A . n 
A 1 574 GLY 574 573 573 GLY GLY A . n 
A 1 575 LEU 575 574 574 LEU LEU A . n 
A 1 576 SER 576 575 575 SER SER A . n 
A 1 577 ALA 577 576 576 ALA ALA A . n 
A 1 578 GLY 578 577 577 GLY GLY A . n 
A 1 579 LEU 579 578 578 LEU LEU A . n 
A 1 580 GLN 580 579 579 GLN GLN A . n 
A 1 581 ALA 581 580 580 ALA ALA A . n 
A 1 582 SER 582 581 581 SER SER A . n 
A 1 583 ASP 583 582 582 ASP ASP A . n 
A 1 584 LEU 584 583 583 LEU LEU A . n 
A 1 585 PRO 585 584 584 PRO PRO A . n 
A 1 586 ALA 586 585 585 ALA ALA A . n 
A 1 587 SER 587 586 586 SER SER A . n 
A 1 588 ALA 588 587 587 ALA ALA A . n 
A 1 589 SER 589 588 588 SER SER A . n 
A 1 590 LEU 590 589 589 LEU LEU A . n 
A 1 591 PRO 591 590 590 PRO PRO A . n 
A 1 592 ALA 592 591 591 ALA ALA A . n 
A 1 593 LYS 593 592 592 LYS LYS A . n 
A 1 594 ALA 594 593 593 ALA ALA A . n 
A 1 595 ASP 595 594 594 ASP ASP A . n 
A 1 596 LEU 596 595 595 LEU LEU A . n 
A 1 597 LEU 597 596 596 LEU LEU A . n 
A 1 598 LEU 598 597 597 LEU LEU A . n 
A 1 599 SER 599 598 598 SER SER A . n 
A 1 600 THR 600 599 599 THR THR A . n 
A 1 601 GLN 601 600 600 GLN GLN A . n 
A 1 602 PRO 602 601 601 PRO PRO A . n 
A 1 603 GLY 603 602 602 GLY GLY A . n 
A 1 604 ARG 604 603 603 ARG ARG A . n 
A 1 605 GLU 605 604 604 GLU GLU A . n 
A 1 606 GLU 606 605 605 GLU GLU A . n 
A 1 607 GLY 607 606 606 GLY GLY A . n 
A 1 608 SER 608 607 607 SER SER A . n 
A 1 609 PRO 609 608 608 PRO PRO A . n 
A 1 610 LEU 610 609 609 LEU LEU A . n 
A 1 611 GLU 611 610 610 GLU GLU A . n 
A 1 612 LEU 612 611 611 LEU LEU A . n 
A 1 613 GLU 613 612 612 GLU GLU A . n 
A 1 614 ARG 614 613 613 ARG ARG A . n 
A 1 615 LEU 615 614 614 LEU LEU A . n 
A 1 616 LYS 616 615 615 LYS LYS A . n 
A 1 617 LEU 617 616 616 LEU LEU A . n 
A 1 618 GLU 618 617 617 GLU GLU A . n 
A 1 619 PRO 619 618 618 PRO PRO A . n 
A 1 620 HIS 620 619 619 HIS HIS A . n 
A 1 621 GLU 621 620 620 GLU GLU A . n 
A 1 622 GLY 622 621 621 GLY GLY A . n 
A 1 623 LEU 623 622 622 LEU LEU A . n 
A 1 624 LEU 624 623 623 LEU LEU A . n 
A 1 625 LEU 625 624 624 LEU LEU A . n 
A 1 626 ARG 626 625 625 ARG ARG A . n 
A 1 627 PHE 627 626 626 PHE PHE A . n 
A 1 628 PRO 628 627 627 PRO PRO A . n 
A 1 629 TYR 629 628 628 TYR TYR A . n 
A 1 630 ALA 630 629 629 ALA ALA A . n 
A 1 631 ALA 631 630 630 ALA ALA A . n 
B 2 1   MET 1   1   ?   ?   ?   B . n 
B 2 2   ALA 2   2   ?   ?   ?   B . n 
B 2 3   GLY 3   3   ?   ?   ?   B . n 
B 2 4   ALA 4   4   ?   ?   ?   B . n 
B 2 5   GLY 5   5   ?   ?   ?   B . n 
B 2 6   PRO 6   6   ?   ?   ?   B . n 
B 2 7   LYS 7   7   ?   ?   ?   B . n 
B 2 8   ARG 8   8   ?   ?   ?   B . n 
B 2 9   ARG 9   9   ?   ?   ?   B . n 
B 2 10  ALA 10  10  ?   ?   ?   B . n 
B 2 11  LEU 11  11  ?   ?   ?   B . n 
B 2 12  ALA 12  12  ?   ?   ?   B . n 
B 2 13  ALA 13  13  ?   ?   ?   B . n 
B 2 14  PRO 14  14  ?   ?   ?   B . n 
B 2 15  ALA 15  15  ?   ?   ?   B . n 
B 2 16  ALA 16  16  ?   ?   ?   B . n 
B 2 17  GLU 17  17  ?   ?   ?   B . n 
B 2 18  GLU 18  18  ?   ?   ?   B . n 
B 2 19  LYS 19  19  ?   ?   ?   B . n 
B 2 20  GLU 20  20  ?   ?   ?   B . n 
B 2 21  GLU 21  21  ?   ?   ?   B . n 
B 2 22  ALA 22  22  ?   ?   ?   B . n 
B 2 23  ARG 23  23  ?   ?   ?   B . n 
B 2 24  GLU 24  24  ?   ?   ?   B . n 
B 2 25  LYS 25  25  ?   ?   ?   B . n 
B 2 26  MET 26  26  ?   ?   ?   B . n 
B 2 27  LEU 27  27  ?   ?   ?   B . n 
B 2 28  ALA 28  28  ?   ?   ?   B . n 
B 2 29  ALA 29  29  ?   ?   ?   B . n 
B 2 30  LYS 30  30  ?   ?   ?   B . n 
B 2 31  SER 31  31  ?   ?   ?   B . n 
B 2 32  ALA 32  32  ?   ?   ?   B . n 
B 2 33  ASP 33  33  ?   ?   ?   B . n 
B 2 34  GLY 34  34  ?   ?   ?   B . n 
B 2 35  SER 35  35  ?   ?   ?   B . n 
B 2 36  ALA 36  36  ?   ?   ?   B . n 
B 2 37  PRO 37  37  ?   ?   ?   B . n 
B 2 38  ALA 38  38  ?   ?   ?   B . n 
B 2 39  GLY 39  39  ?   ?   ?   B . n 
B 2 40  GLU 40  40  ?   ?   ?   B . n 
B 2 41  GLY 41  41  ?   ?   ?   B . n 
B 2 42  GLU 42  42  ?   ?   ?   B . n 
B 2 43  GLY 43  43  ?   ?   ?   B . n 
B 2 44  VAL 44  44  ?   ?   ?   B . n 
B 2 45  THR 45  45  ?   ?   ?   B . n 
B 2 46  LEU 46  46  ?   ?   ?   B . n 
B 2 47  GLN 47  47  ?   ?   ?   B . n 
B 2 48  ARG 48  48  ?   ?   ?   B . n 
B 2 49  ASN 49  49  ?   ?   ?   B . n 
B 2 50  ILE 50  50  ?   ?   ?   B . n 
B 2 51  THR 51  51  51  THR THR B . n 
B 2 52  LEU 52  52  52  LEU LEU B . n 
B 2 53  LEU 53  53  53  LEU LEU B . n 
B 2 54  ASN 54  54  54  ASN ASN B . n 
B 2 55  GLY 55  55  55  GLY GLY B . n 
B 2 56  VAL 56  56  56  VAL VAL B . n 
B 2 57  ALA 57  57  57  ALA ALA B . n 
B 2 58  ILE 58  58  58  ILE ILE B . n 
B 2 59  ILE 59  59  59  ILE ILE B . n 
B 2 60  VAL 60  60  60  VAL VAL B . n 
B 2 61  GLY 61  61  61  GLY GLY B . n 
B 2 62  THR 62  62  62  THR THR B . n 
B 2 63  ILE 63  63  63  ILE ILE B . n 
B 2 64  ILE 64  64  64  ILE ILE B . n 
B 2 65  GLY 65  65  65  GLY GLY B . n 
B 2 66  SER 66  66  66  SER SER B . n 
B 2 67  GLY 67  67  67  GLY GLY B . n 
B 2 68  ILE 68  68  68  ILE ILE B . n 
B 2 69  PHE 69  69  69  PHE PHE B . n 
B 2 70  VAL 70  70  70  VAL VAL B . n 
B 2 71  THR 71  71  71  THR THR B . n 
B 2 72  PRO 72  72  72  PRO PRO B . n 
B 2 73  THR 73  73  73  THR THR B . n 
B 2 74  GLY 74  74  74  GLY GLY B . n 
B 2 75  VAL 75  75  75  VAL VAL B . n 
B 2 76  LEU 76  76  76  LEU LEU B . n 
B 2 77  LYS 77  77  77  LYS LYS B . n 
B 2 78  GLU 78  78  78  GLU GLU B . n 
B 2 79  ALA 79  79  79  ALA ALA B . n 
B 2 80  GLY 80  80  80  GLY GLY B . n 
B 2 81  SER 81  81  81  SER SER B . n 
B 2 82  PRO 82  82  82  PRO PRO B . n 
B 2 83  GLY 83  83  83  GLY GLY B . n 
B 2 84  LEU 84  84  84  LEU LEU B . n 
B 2 85  ALA 85  85  85  ALA ALA B . n 
B 2 86  LEU 86  86  86  LEU LEU B . n 
B 2 87  VAL 87  87  87  VAL VAL B . n 
B 2 88  VAL 88  88  88  VAL VAL B . n 
B 2 89  TRP 89  89  89  TRP TRP B . n 
B 2 90  ALA 90  90  90  ALA ALA B . n 
B 2 91  ALA 91  91  91  ALA ALA B . n 
B 2 92  CYS 92  92  92  CYS CYS B . n 
B 2 93  GLY 93  93  93  GLY GLY B . n 
B 2 94  VAL 94  94  94  VAL VAL B . n 
B 2 95  PHE 95  95  95  PHE PHE B . n 
B 2 96  SER 96  96  96  SER SER B . n 
B 2 97  ILE 97  97  97  ILE ILE B . n 
B 2 98  VAL 98  98  98  VAL VAL B . n 
B 2 99  GLY 99  99  99  GLY GLY B . n 
B 2 100 ALA 100 100 100 ALA ALA B . n 
B 2 101 LEU 101 101 101 LEU LEU B . n 
B 2 102 CYS 102 102 102 CYS CYS B . n 
B 2 103 TYR 103 103 103 TYR TYR B . n 
B 2 104 ALA 104 104 104 ALA ALA B . n 
B 2 105 GLU 105 105 105 GLU GLU B . n 
B 2 106 LEU 106 106 106 LEU LEU B . n 
B 2 107 GLY 107 107 107 GLY GLY B . n 
B 2 108 THR 108 108 108 THR THR B . n 
B 2 109 THR 109 109 109 THR THR B . n 
B 2 110 ILE 110 110 110 ILE ILE B . n 
B 2 111 SER 111 111 111 SER SER B . n 
B 2 112 LYS 112 112 112 LYS LYS B . n 
B 2 113 SER 113 113 113 SER SER B . n 
B 2 114 GLY 114 114 114 GLY GLY B . n 
B 2 115 GLY 115 115 115 GLY GLY B . n 
B 2 116 ASP 116 116 116 ASP ASP B . n 
B 2 117 TYR 117 117 117 TYR TYR B . n 
B 2 118 ALA 118 118 118 ALA ALA B . n 
B 2 119 TYR 119 119 119 TYR TYR B . n 
B 2 120 MET 120 120 120 MET MET B . n 
B 2 121 LEU 121 121 121 LEU LEU B . n 
B 2 122 GLU 122 122 122 GLU GLU B . n 
B 2 123 VAL 123 123 123 VAL VAL B . n 
B 2 124 TYR 124 124 124 TYR TYR B . n 
B 2 125 GLY 125 125 125 GLY GLY B . n 
B 2 126 SER 126 126 126 SER SER B . n 
B 2 127 LEU 127 127 127 LEU LEU B . n 
B 2 128 PRO 128 128 128 PRO PRO B . n 
B 2 129 ALA 129 129 129 ALA ALA B . n 
B 2 130 PHE 130 130 130 PHE PHE B . n 
B 2 131 LEU 131 131 131 LEU LEU B . n 
B 2 132 LYS 132 132 132 LYS LYS B . n 
B 2 133 LEU 133 133 133 LEU LEU B . n 
B 2 134 TRP 134 134 134 TRP TRP B . n 
B 2 135 ILE 135 135 135 ILE ILE B . n 
B 2 136 GLU 136 136 136 GLU GLU B . n 
B 2 137 LEU 137 137 137 LEU LEU B . n 
B 2 138 LEU 138 138 138 LEU LEU B . n 
B 2 139 ILE 139 139 139 ILE ILE B . n 
B 2 140 ILE 140 140 140 ILE ILE B . n 
B 2 141 ARG 141 141 141 ARG ARG B . n 
B 2 142 PRO 142 142 142 PRO PRO B . n 
B 2 143 SER 143 143 143 SER SER B . n 
B 2 144 SER 144 144 144 SER SER B . n 
B 2 145 GLN 145 145 145 GLN GLN B . n 
B 2 146 TYR 146 146 146 TYR TYR B . n 
B 2 147 ILE 147 147 147 ILE ILE B . n 
B 2 148 VAL 148 148 148 VAL VAL B . n 
B 2 149 ALA 149 149 149 ALA ALA B . n 
B 2 150 LEU 150 150 150 LEU LEU B . n 
B 2 151 VAL 151 151 151 VAL VAL B . n 
B 2 152 PHE 152 152 152 PHE PHE B . n 
B 2 153 ALA 153 153 153 ALA ALA B . n 
B 2 154 THR 154 154 154 THR THR B . n 
B 2 155 TYR 155 155 155 TYR TYR B . n 
B 2 156 LEU 156 156 156 LEU LEU B . n 
B 2 157 LEU 157 157 157 LEU LEU B . n 
B 2 158 LYS 158 158 158 LYS LYS B . n 
B 2 159 PRO 159 159 159 PRO PRO B . n 
B 2 160 LEU 160 160 160 LEU LEU B . n 
B 2 161 PHE 161 161 161 PHE PHE B . n 
B 2 162 PRO 162 162 162 PRO PRO B . n 
B 2 163 THR 163 163 163 THR THR B . n 
B 2 164 CYS 164 164 164 CYS CYS B . n 
B 2 165 PRO 165 165 165 PRO PRO B . n 
B 2 166 VAL 166 166 166 VAL VAL B . n 
B 2 167 PRO 167 167 167 PRO PRO B . n 
B 2 168 GLU 168 168 168 GLU GLU B . n 
B 2 169 GLU 169 169 169 GLU GLU B . n 
B 2 170 ALA 170 170 170 ALA ALA B . n 
B 2 171 ALA 171 171 171 ALA ALA B . n 
B 2 172 LYS 172 172 172 LYS LYS B . n 
B 2 173 LEU 173 173 173 LEU LEU B . n 
B 2 174 VAL 174 174 174 VAL VAL B . n 
B 2 175 ALA 175 175 175 ALA ALA B . n 
B 2 176 CYS 176 176 176 CYS CYS B . n 
B 2 177 LEU 177 177 177 LEU LEU B . n 
B 2 178 CYS 178 178 178 CYS CYS B . n 
B 2 179 VAL 179 179 179 VAL VAL B . n 
B 2 180 LEU 180 180 180 LEU LEU B . n 
B 2 181 LEU 181 181 181 LEU LEU B . n 
B 2 182 LEU 182 182 182 LEU LEU B . n 
B 2 183 THR 183 183 183 THR THR B . n 
B 2 184 ALA 184 184 184 ALA ALA B . n 
B 2 185 VAL 185 185 185 VAL VAL B . n 
B 2 186 ASN 186 186 186 ASN ASN B . n 
B 2 187 CYS 187 187 187 CYS CYS B . n 
B 2 188 TYR 188 188 188 TYR TYR B . n 
B 2 189 SER 189 189 189 SER SER B . n 
B 2 190 VAL 190 190 190 VAL VAL B . n 
B 2 191 LYS 191 191 191 LYS LYS B . n 
B 2 192 ALA 192 192 192 ALA ALA B . n 
B 2 193 ALA 193 193 193 ALA ALA B . n 
B 2 194 THR 194 194 194 THR THR B . n 
B 2 195 ARG 195 195 195 ARG ARG B . n 
B 2 196 VAL 196 196 196 VAL VAL B . n 
B 2 197 GLN 197 197 197 GLN GLN B . n 
B 2 198 ASP 198 198 198 ASP ASP B . n 
B 2 199 ALA 199 199 199 ALA ALA B . n 
B 2 200 PHE 200 200 200 PHE PHE B . n 
B 2 201 ALA 201 201 201 ALA ALA B . n 
B 2 202 ALA 202 202 202 ALA ALA B . n 
B 2 203 ALA 203 203 203 ALA ALA B . n 
B 2 204 LYS 204 204 204 LYS LYS B . n 
B 2 205 LEU 205 205 205 LEU LEU B . n 
B 2 206 LEU 206 206 206 LEU LEU B . n 
B 2 207 ALA 207 207 207 ALA ALA B . n 
B 2 208 LEU 208 208 208 LEU LEU B . n 
B 2 209 ALA 209 209 209 ALA ALA B . n 
B 2 210 LEU 210 210 210 LEU LEU B . n 
B 2 211 ILE 211 211 211 ILE ILE B . n 
B 2 212 ILE 212 212 212 ILE ILE B . n 
B 2 213 LEU 213 213 213 LEU LEU B . n 
B 2 214 LEU 214 214 214 LEU LEU B . n 
B 2 215 GLY 215 215 215 GLY GLY B . n 
B 2 216 PHE 216 216 216 PHE PHE B . n 
B 2 217 VAL 217 217 217 VAL VAL B . n 
B 2 218 GLN 218 218 218 GLN GLN B . n 
B 2 219 ILE 219 219 219 ILE ILE B . n 
B 2 220 GLY 220 220 220 GLY GLY B . n 
B 2 221 LYS 221 221 221 LYS LYS B . n 
B 2 222 GLY 222 222 222 GLY GLY B . n 
B 2 223 ASP 223 223 ?   ?   ?   B . n 
B 2 224 VAL 224 224 ?   ?   ?   B . n 
B 2 225 SER 225 225 ?   ?   ?   B . n 
B 2 226 ASN 226 226 ?   ?   ?   B . n 
B 2 227 LEU 227 227 ?   ?   ?   B . n 
B 2 228 ASP 228 228 ?   ?   ?   B . n 
B 2 229 PRO 229 229 ?   ?   ?   B . n 
B 2 230 ASN 230 230 ?   ?   ?   B . n 
B 2 231 PHE 231 231 ?   ?   ?   B . n 
B 2 232 SER 232 232 ?   ?   ?   B . n 
B 2 233 PHE 233 233 233 PHE PHE B . n 
B 2 234 GLU 234 234 234 GLU GLU B . n 
B 2 235 GLY 235 235 235 GLY GLY B . n 
B 2 236 THR 236 236 236 THR THR B . n 
B 2 237 LYS 237 237 237 LYS LYS B . n 
B 2 238 LEU 238 238 238 LEU LEU B . n 
B 2 239 ASP 239 239 239 ASP ASP B . n 
B 2 240 VAL 240 240 240 VAL VAL B . n 
B 2 241 GLY 241 241 241 GLY GLY B . n 
B 2 242 ASN 242 242 242 ASN ASN B . n 
B 2 243 ILE 243 243 243 ILE ILE B . n 
B 2 244 VAL 244 244 244 VAL VAL B . n 
B 2 245 LEU 245 245 245 LEU LEU B . n 
B 2 246 ALA 246 246 246 ALA ALA B . n 
B 2 247 LEU 247 247 247 LEU LEU B . n 
B 2 248 TYR 248 248 248 TYR TYR B . n 
B 2 249 SER 249 249 249 SER SER B . n 
B 2 250 GLY 250 250 250 GLY GLY B . n 
B 2 251 LEU 251 251 251 LEU LEU B . n 
B 2 252 PHE 252 252 252 PHE PHE B . n 
B 2 253 ALA 253 253 253 ALA ALA B . n 
B 2 254 TYR 254 254 254 TYR TYR B . n 
B 2 255 GLY 255 255 255 GLY GLY B . n 
B 2 256 GLY 256 256 256 GLY GLY B . n 
B 2 257 TRP 257 257 257 TRP TRP B . n 
B 2 258 ASN 258 258 258 ASN ASN B . n 
B 2 259 TYR 259 259 259 TYR TYR B . n 
B 2 260 LEU 260 260 260 LEU LEU B . n 
B 2 261 ASN 261 261 261 ASN ASN B . n 
B 2 262 PHE 262 262 262 PHE PHE B . n 
B 2 263 VAL 263 263 263 VAL VAL B . n 
B 2 264 THR 264 264 264 THR THR B . n 
B 2 265 GLU 265 265 265 GLU GLU B . n 
B 2 266 GLU 266 266 266 GLU GLU B . n 
B 2 267 MET 267 267 267 MET MET B . n 
B 2 268 ILE 268 268 268 ILE ILE B . n 
B 2 269 ASN 269 269 269 ASN ASN B . n 
B 2 270 PRO 270 270 270 PRO PRO B . n 
B 2 271 TYR 271 271 271 TYR TYR B . n 
B 2 272 ARG 272 272 272 ARG ARG B . n 
B 2 273 ASN 273 273 273 ASN ASN B . n 
B 2 274 LEU 274 274 274 LEU LEU B . n 
B 2 275 PRO 275 275 275 PRO PRO B . n 
B 2 276 LEU 276 276 276 LEU LEU B . n 
B 2 277 ALA 277 277 277 ALA ALA B . n 
B 2 278 ILE 278 278 278 ILE ILE B . n 
B 2 279 ILE 279 279 279 ILE ILE B . n 
B 2 280 ILE 280 280 280 ILE ILE B . n 
B 2 281 SER 281 281 281 SER SER B . n 
B 2 282 LEU 282 282 282 LEU LEU B . n 
B 2 283 PRO 283 283 283 PRO PRO B . n 
B 2 284 ILE 284 284 284 ILE ILE B . n 
B 2 285 VAL 285 285 285 VAL VAL B . n 
B 2 286 THR 286 286 286 THR THR B . n 
B 2 287 LEU 287 287 287 LEU LEU B . n 
B 2 288 VAL 288 288 288 VAL VAL B . n 
B 2 289 TYR 289 289 289 TYR TYR B . n 
B 2 290 VAL 290 290 290 VAL VAL B . n 
B 2 291 LEU 291 291 291 LEU LEU B . n 
B 2 292 THR 292 292 292 THR THR B . n 
B 2 293 ASN 293 293 293 ASN ASN B . n 
B 2 294 LEU 294 294 294 LEU LEU B . n 
B 2 295 ALA 295 295 295 ALA ALA B . n 
B 2 296 TYR 296 296 296 TYR TYR B . n 
B 2 297 PHE 297 297 297 PHE PHE B . n 
B 2 298 THR 298 298 298 THR THR B . n 
B 2 299 THR 299 299 299 THR THR B . n 
B 2 300 LEU 300 300 300 LEU LEU B . n 
B 2 301 SER 301 301 301 SER SER B . n 
B 2 302 THR 302 302 302 THR THR B . n 
B 2 303 GLU 303 303 303 GLU GLU B . n 
B 2 304 GLN 304 304 304 GLN GLN B . n 
B 2 305 MET 305 305 305 MET MET B . n 
B 2 306 LEU 306 306 306 LEU LEU B . n 
B 2 307 SER 307 307 307 SER SER B . n 
B 2 308 SER 308 308 308 SER SER B . n 
B 2 309 GLU 309 309 309 GLU GLU B . n 
B 2 310 ALA 310 310 310 ALA ALA B . n 
B 2 311 VAL 311 311 311 VAL VAL B . n 
B 2 312 ALA 312 312 312 ALA ALA B . n 
B 2 313 VAL 313 313 313 VAL VAL B . n 
B 2 314 ASP 314 314 314 ASP ASP B . n 
B 2 315 PHE 315 315 315 PHE PHE B . n 
B 2 316 GLY 316 316 316 GLY GLY B . n 
B 2 317 ASN 317 317 317 ASN ASN B . n 
B 2 318 TYR 318 318 318 TYR TYR B . n 
B 2 319 HIS 319 319 319 HIS HIS B . n 
B 2 320 LEU 320 320 320 LEU LEU B . n 
B 2 321 GLY 321 321 321 GLY GLY B . n 
B 2 322 VAL 322 322 322 VAL VAL B . n 
B 2 323 MET 323 323 323 MET MET B . n 
B 2 324 SER 324 324 324 SER SER B . n 
B 2 325 TRP 325 325 325 TRP TRP B . n 
B 2 326 ILE 326 326 326 ILE ILE B . n 
B 2 327 ILE 327 327 327 ILE ILE B . n 
B 2 328 PRO 328 328 328 PRO PRO B . n 
B 2 329 VAL 329 329 329 VAL VAL B . n 
B 2 330 PHE 330 330 330 PHE PHE B . n 
B 2 331 VAL 331 331 331 VAL VAL B . n 
B 2 332 GLY 332 332 332 GLY GLY B . n 
B 2 333 LEU 333 333 333 LEU LEU B . n 
B 2 334 SER 334 334 334 SER SER B . n 
B 2 335 CYS 335 335 335 CYS CYS B . n 
B 2 336 PHE 336 336 336 PHE PHE B . n 
B 2 337 GLY 337 337 337 GLY GLY B . n 
B 2 338 SER 338 338 338 SER SER B . n 
B 2 339 VAL 339 339 339 VAL VAL B . n 
B 2 340 ASN 340 340 340 ASN ASN B . n 
B 2 341 GLY 341 341 341 GLY GLY B . n 
B 2 342 SER 342 342 342 SER SER B . n 
B 2 343 LEU 343 343 343 LEU LEU B . n 
B 2 344 PHE 344 344 344 PHE PHE B . n 
B 2 345 THR 345 345 345 THR THR B . n 
B 2 346 SER 346 346 346 SER SER B . n 
B 2 347 SER 347 347 347 SER SER B . n 
B 2 348 ARG 348 348 348 ARG ARG B . n 
B 2 349 LEU 349 349 349 LEU LEU B . n 
B 2 350 PHE 350 350 350 PHE PHE B . n 
B 2 351 PHE 351 351 351 PHE PHE B . n 
B 2 352 VAL 352 352 352 VAL VAL B . n 
B 2 353 GLY 353 353 353 GLY GLY B . n 
B 2 354 SER 354 354 354 SER SER B . n 
B 2 355 ARG 355 355 355 ARG ARG B . n 
B 2 356 GLU 356 356 356 GLU GLU B . n 
B 2 357 GLY 357 357 357 GLY GLY B . n 
B 2 358 HIS 358 358 358 HIS HIS B . n 
B 2 359 LEU 359 359 359 LEU LEU B . n 
B 2 360 PRO 360 360 360 PRO PRO B . n 
B 2 361 SER 361 361 361 SER SER B . n 
B 2 362 ILE 362 362 362 ILE ILE B . n 
B 2 363 LEU 363 363 363 LEU LEU B . n 
B 2 364 SER 364 364 364 SER SER B . n 
B 2 365 MET 365 365 365 MET MET B . n 
B 2 366 ILE 366 366 366 ILE ILE B . n 
B 2 367 HIS 367 367 367 HIS HIS B . n 
B 2 368 PRO 368 368 368 PRO PRO B . n 
B 2 369 GLN 369 369 369 GLN GLN B . n 
B 2 370 LEU 370 370 370 LEU LEU B . n 
B 2 371 LEU 371 371 371 LEU LEU B . n 
B 2 372 THR 372 372 372 THR THR B . n 
B 2 373 PRO 373 373 373 PRO PRO B . n 
B 2 374 VAL 374 374 374 VAL VAL B . n 
B 2 375 PRO 375 375 375 PRO PRO B . n 
B 2 376 SER 376 376 376 SER SER B . n 
B 2 377 LEU 377 377 377 LEU LEU B . n 
B 2 378 VAL 378 378 378 VAL VAL B . n 
B 2 379 PHE 379 379 379 PHE PHE B . n 
B 2 380 THR 380 380 380 THR THR B . n 
B 2 381 CYS 381 381 381 CYS CYS B . n 
B 2 382 VAL 382 382 382 VAL VAL B . n 
B 2 383 MET 383 383 383 MET MET B . n 
B 2 384 THR 384 384 384 THR THR B . n 
B 2 385 LEU 385 385 385 LEU LEU B . n 
B 2 386 LEU 386 386 386 LEU LEU B . n 
B 2 387 TYR 387 387 387 TYR TYR B . n 
B 2 388 ALA 388 388 388 ALA ALA B . n 
B 2 389 PHE 389 389 389 PHE PHE B . n 
B 2 390 SER 390 390 390 SER SER B . n 
B 2 391 LYS 391 391 391 LYS LYS B . n 
B 2 392 ASP 392 392 392 ASP ASP B . n 
B 2 393 ILE 393 393 393 ILE ILE B . n 
B 2 394 PHE 394 394 394 PHE PHE B . n 
B 2 395 SER 395 395 395 SER SER B . n 
B 2 396 VAL 396 396 396 VAL VAL B . n 
B 2 397 ILE 397 397 397 ILE ILE B . n 
B 2 398 ASN 398 398 398 ASN ASN B . n 
B 2 399 PHE 399 399 399 PHE PHE B . n 
B 2 400 PHE 400 400 400 PHE PHE B . n 
B 2 401 SER 401 401 401 SER SER B . n 
B 2 402 PHE 402 402 402 PHE PHE B . n 
B 2 403 PHE 403 403 403 PHE PHE B . n 
B 2 404 ASN 404 404 404 ASN ASN B . n 
B 2 405 TRP 405 405 405 TRP TRP B . n 
B 2 406 LEU 406 406 406 LEU LEU B . n 
B 2 407 CYS 407 407 407 CYS CYS B . n 
B 2 408 VAL 408 408 408 VAL VAL B . n 
B 2 409 ALA 409 409 409 ALA ALA B . n 
B 2 410 LEU 410 410 410 LEU LEU B . n 
B 2 411 ALA 411 411 411 ALA ALA B . n 
B 2 412 ILE 412 412 412 ILE ILE B . n 
B 2 413 ILE 413 413 413 ILE ILE B . n 
B 2 414 GLY 414 414 414 GLY GLY B . n 
B 2 415 MET 415 415 415 MET MET B . n 
B 2 416 ILE 416 416 416 ILE ILE B . n 
B 2 417 TRP 417 417 417 TRP TRP B . n 
B 2 418 LEU 418 418 418 LEU LEU B . n 
B 2 419 ARG 419 419 419 ARG ARG B . n 
B 2 420 HIS 420 420 420 HIS HIS B . n 
B 2 421 ARG 421 421 421 ARG ARG B . n 
B 2 422 LYS 422 422 422 LYS LYS B . n 
B 2 423 PRO 423 423 423 PRO PRO B . n 
B 2 424 GLU 424 424 424 GLU GLU B . n 
B 2 425 LEU 425 425 425 LEU LEU B . n 
B 2 426 GLU 426 426 426 GLU GLU B . n 
B 2 427 ARG 427 427 427 ARG ARG B . n 
B 2 428 PRO 428 428 428 PRO PRO B . n 
B 2 429 ILE 429 429 429 ILE ILE B . n 
B 2 430 LYS 430 430 430 LYS LYS B . n 
B 2 431 VAL 431 431 431 VAL VAL B . n 
B 2 432 ASN 432 432 432 ASN ASN B . n 
B 2 433 LEU 433 433 433 LEU LEU B . n 
B 2 434 ALA 434 434 434 ALA ALA B . n 
B 2 435 LEU 435 435 435 LEU LEU B . n 
B 2 436 PRO 436 436 436 PRO PRO B . n 
B 2 437 VAL 437 437 437 VAL VAL B . n 
B 2 438 PHE 438 438 438 PHE PHE B . n 
B 2 439 PHE 439 439 439 PHE PHE B . n 
B 2 440 ILE 440 440 440 ILE ILE B . n 
B 2 441 LEU 441 441 441 LEU LEU B . n 
B 2 442 ALA 442 442 442 ALA ALA B . n 
B 2 443 CYS 443 443 443 CYS CYS B . n 
B 2 444 LEU 444 444 444 LEU LEU B . n 
B 2 445 PHE 445 445 445 PHE PHE B . n 
B 2 446 LEU 446 446 446 LEU LEU B . n 
B 2 447 ILE 447 447 447 ILE ILE B . n 
B 2 448 ALA 448 448 448 ALA ALA B . n 
B 2 449 VAL 449 449 449 VAL VAL B . n 
B 2 450 SER 450 450 450 SER SER B . n 
B 2 451 PHE 451 451 451 PHE PHE B . n 
B 2 452 TRP 452 452 452 TRP TRP B . n 
B 2 453 LYS 453 453 453 LYS LYS B . n 
B 2 454 THR 454 454 454 THR THR B . n 
B 2 455 PRO 455 455 455 PRO PRO B . n 
B 2 456 VAL 456 456 456 VAL VAL B . n 
B 2 457 GLU 457 457 457 GLU GLU B . n 
B 2 458 CYS 458 458 458 CYS CYS B . n 
B 2 459 GLY 459 459 459 GLY GLY B . n 
B 2 460 ILE 460 460 460 ILE ILE B . n 
B 2 461 GLY 461 461 461 GLY GLY B . n 
B 2 462 PHE 462 462 462 PHE PHE B . n 
B 2 463 THR 463 463 463 THR THR B . n 
B 2 464 ILE 464 464 464 ILE ILE B . n 
B 2 465 ILE 465 465 465 ILE ILE B . n 
B 2 466 LEU 466 466 466 LEU LEU B . n 
B 2 467 SER 467 467 467 SER SER B . n 
B 2 468 GLY 468 468 468 GLY GLY B . n 
B 2 469 LEU 469 469 469 LEU LEU B . n 
B 2 470 PRO 470 470 470 PRO PRO B . n 
B 2 471 VAL 471 471 471 VAL VAL B . n 
B 2 472 TYR 472 472 472 TYR TYR B . n 
B 2 473 PHE 473 473 473 PHE PHE B . n 
B 2 474 PHE 474 474 474 PHE PHE B . n 
B 2 475 GLY 475 475 475 GLY GLY B . n 
B 2 476 VAL 476 476 476 VAL VAL B . n 
B 2 477 TRP 477 477 477 TRP TRP B . n 
B 2 478 TRP 478 478 478 TRP TRP B . n 
B 2 479 LYS 479 479 479 LYS LYS B . n 
B 2 480 ASN 480 480 480 ASN ASN B . n 
B 2 481 LYS 481 481 481 LYS LYS B . n 
B 2 482 PRO 482 482 482 PRO PRO B . n 
B 2 483 LYS 483 483 483 LYS LYS B . n 
B 2 484 TRP 484 484 484 TRP TRP B . n 
B 2 485 LEU 485 485 485 LEU LEU B . n 
B 2 486 LEU 486 486 486 LEU LEU B . n 
B 2 487 GLN 487 487 487 GLN GLN B . n 
B 2 488 GLY 488 488 488 GLY GLY B . n 
B 2 489 ILE 489 489 489 ILE ILE B . n 
B 2 490 PHE 490 490 490 PHE PHE B . n 
B 2 491 SER 491 491 491 SER SER B . n 
B 2 492 THR 492 492 492 THR THR B . n 
B 2 493 THR 493 493 493 THR THR B . n 
B 2 494 VAL 494 494 494 VAL VAL B . n 
B 2 495 LEU 495 495 495 LEU LEU B . n 
B 2 496 CYS 496 496 496 CYS CYS B . n 
B 2 497 GLN 497 497 497 GLN GLN B . n 
B 2 498 LYS 498 498 498 LYS LYS B . n 
B 2 499 LEU 499 499 499 LEU LEU B . n 
B 2 500 MET 500 500 500 MET MET B . n 
B 2 501 GLN 501 501 501 GLN GLN B . n 
B 2 502 VAL 502 502 502 VAL VAL B . n 
B 2 503 VAL 503 503 503 VAL VAL B . n 
B 2 504 PRO 504 504 504 PRO PRO B . n 
B 2 505 GLN 505 505 505 GLN GLN B . n 
B 2 506 GLU 506 506 506 GLU GLU B . n 
B 2 507 THR 507 507 507 THR THR B . n 
B 2 508 ASP 508 508 ?   ?   ?   B . n 
B 2 509 TYR 509 509 ?   ?   ?   B . n 
B 2 510 LYS 510 510 ?   ?   ?   B . n 
B 2 511 ASP 511 511 ?   ?   ?   B . n 
B 2 512 ASP 512 512 ?   ?   ?   B . n 
B 2 513 ASP 513 513 ?   ?   ?   B . n 
B 2 514 ASP 514 514 ?   ?   ?   B . n 
B 2 515 LYS 515 515 ?   ?   ?   B . n 
C 3 1   ASP 1   1   1   ASP ASP L . n 
C 3 2   ILE 2   2   2   ILE ILE L . n 
C 3 3   VAL 3   3   3   VAL VAL L . n 
C 3 4   LEU 4   4   4   LEU LEU L . n 
C 3 5   THR 5   5   5   THR THR L . n 
C 3 6   GLN 6   6   6   GLN GLN L . n 
C 3 7   SER 7   7   7   SER SER L . n 
C 3 8   PRO 8   8   8   PRO PRO L . n 
C 3 9   SER 9   9   9   SER SER L . n 
C 3 10  SER 10  10  10  SER SER L . n 
C 3 11  LEU 11  11  11  LEU LEU L . n 
C 3 12  ALA 12  12  12  ALA ALA L . n 
C 3 13  MET 13  13  13  MET MET L . n 
C 3 14  SER 14  14  14  SER SER L . n 
C 3 15  VAL 15  15  15  VAL VAL L . n 
C 3 16  GLY 16  16  16  GLY GLY L . n 
C 3 17  GLN 17  17  17  GLN GLN L . n 
C 3 18  LYS 18  18  18  LYS LYS L . n 
C 3 19  VAL 19  19  19  VAL VAL L . n 
C 3 20  THR 20  20  20  THR THR L . n 
C 3 21  MET 21  21  21  MET MET L . n 
C 3 22  ASN 22  22  22  ASN ASN L . n 
C 3 23  CYS 23  23  23  CYS CYS L . n 
C 3 24  LYS 24  24  24  LYS LYS L . n 
C 3 25  SER 25  25  25  SER SER L . n 
C 3 26  SER 26  26  26  SER SER L . n 
C 3 27  GLN 27  27  27  GLN GLN L . n 
C 3 28  SER 28  28  28  SER SER L . n 
C 3 29  LEU 29  29  29  LEU LEU L . n 
C 3 30  LEU 30  30  30  LEU LEU L . n 
C 3 31  ASN 31  31  31  ASN ASN L . n 
C 3 32  ASN 32  32  32  ASN ASN L . n 
C 3 33  ASN 33  33  33  ASN ASN L . n 
C 3 34  ASN 34  34  34  ASN ASN L . n 
C 3 35  GLN 35  35  35  GLN GLN L . n 
C 3 36  LYS 36  36  36  LYS LYS L . n 
C 3 37  ASN 37  37  37  ASN ASN L . n 
C 3 38  TYR 38  38  38  TYR TYR L . n 
C 3 39  LEU 39  39  39  LEU LEU L . n 
C 3 40  ALA 40  40  40  ALA ALA L . n 
C 3 41  TRP 41  41  41  TRP TRP L . n 
C 3 42  TYR 42  42  42  TYR TYR L . n 
C 3 43  GLN 43  43  43  GLN GLN L . n 
C 3 44  GLN 44  44  44  GLN GLN L . n 
C 3 45  LYS 45  45  45  LYS LYS L . n 
C 3 46  PRO 46  46  46  PRO PRO L . n 
C 3 47  GLY 47  47  47  GLY GLY L . n 
C 3 48  GLN 48  48  48  GLN GLN L . n 
C 3 49  SER 49  49  49  SER SER L . n 
C 3 50  PRO 50  50  50  PRO PRO L . n 
C 3 51  LYS 51  51  51  LYS LYS L . n 
C 3 52  LEU 52  52  52  LEU LEU L . n 
C 3 53  LEU 53  53  53  LEU LEU L . n 
C 3 54  VAL 54  54  54  VAL VAL L . n 
C 3 55  TYR 55  55  55  TYR TYR L . n 
C 3 56  PHE 56  56  56  PHE PHE L . n 
C 3 57  THR 57  57  57  THR THR L . n 
C 3 58  SER 58  58  58  SER SER L . n 
C 3 59  THR 59  59  59  THR THR L . n 
C 3 60  ARG 60  60  60  ARG ARG L . n 
C 3 61  GLU 61  61  61  GLU GLU L . n 
C 3 62  SER 62  62  62  SER SER L . n 
C 3 63  GLY 63  63  63  GLY GLY L . n 
C 3 64  VAL 64  64  64  VAL VAL L . n 
C 3 65  PRO 65  65  65  PRO PRO L . n 
C 3 66  ASP 66  66  66  ASP ASP L . n 
C 3 67  ARG 67  67  67  ARG ARG L . n 
C 3 68  PHE 68  68  68  PHE PHE L . n 
C 3 69  ILE 69  69  69  ILE ILE L . n 
C 3 70  GLY 70  70  70  GLY GLY L . n 
C 3 71  SER 71  71  71  SER SER L . n 
C 3 72  GLY 72  72  72  GLY GLY L . n 
C 3 73  SER 73  73  73  SER SER L . n 
C 3 74  GLY 74  74  74  GLY GLY L . n 
C 3 75  THR 75  75  75  THR THR L . n 
C 3 76  ASP 76  76  76  ASP ASP L . n 
C 3 77  PHE 77  77  77  PHE PHE L . n 
C 3 78  THR 78  78  78  THR THR L . n 
C 3 79  LEU 79  79  79  LEU LEU L . n 
C 3 80  THR 80  80  80  THR THR L . n 
C 3 81  ILE 81  81  81  ILE ILE L . n 
C 3 82  SER 82  82  82  SER SER L . n 
C 3 83  SER 83  83  83  SER SER L . n 
C 3 84  VAL 84  84  84  VAL VAL L . n 
C 3 85  GLN 85  85  85  GLN GLN L . n 
C 3 86  ALA 86  86  86  ALA ALA L . n 
C 3 87  GLU 87  87  87  GLU GLU L . n 
C 3 88  ASP 88  88  88  ASP ASP L . n 
C 3 89  LEU 89  89  89  LEU LEU L . n 
C 3 90  ALA 90  90  90  ALA ALA L . n 
C 3 91  LEU 91  91  91  LEU LEU L . n 
C 3 92  TYR 92  92  92  TYR TYR L . n 
C 3 93  TYR 93  93  93  TYR TYR L . n 
C 3 94  CYS 94  94  94  CYS CYS L . n 
C 3 95  GLN 95  95  95  GLN GLN L . n 
C 3 96  GLN 96  96  96  GLN GLN L . n 
C 3 97  HIS 97  97  97  HIS HIS L . n 
C 3 98  TYR 98  98  98  TYR TYR L . n 
C 3 99  THR 99  99  99  THR THR L . n 
C 3 100 ILE 100 100 100 ILE ILE L . n 
C 3 101 PRO 101 101 101 PRO PRO L . n 
C 3 102 PRO 102 102 102 PRO PRO L . n 
C 3 103 THR 103 103 103 THR THR L . n 
C 3 104 PHE 104 104 104 PHE PHE L . n 
C 3 105 GLY 105 105 105 GLY GLY L . n 
C 3 106 GLY 106 106 106 GLY GLY L . n 
C 3 107 GLY 107 107 107 GLY GLY L . n 
C 3 108 THR 108 108 108 THR THR L . n 
C 3 109 LYS 109 109 109 LYS LYS L . n 
C 3 110 LEU 110 110 110 LEU LEU L . n 
C 3 111 GLU 111 111 111 GLU GLU L . n 
C 3 112 ILE 112 112 112 ILE ILE L . n 
C 3 113 LYS 113 113 113 LYS LYS L . n 
C 3 114 ARG 114 114 114 ARG ARG L . n 
C 3 115 ALA 115 115 115 ALA ALA L . n 
C 3 116 ASP 116 116 116 ASP ASP L . n 
C 3 117 ALA 117 117 117 ALA ALA L . n 
C 3 118 ALA 118 118 118 ALA ALA L . n 
C 3 119 PRO 119 119 119 PRO PRO L . n 
C 3 120 THR 120 120 120 THR THR L . n 
C 3 121 VAL 121 121 121 VAL VAL L . n 
C 3 122 SER 122 122 122 SER SER L . n 
C 3 123 ILE 123 123 123 ILE ILE L . n 
C 3 124 PHE 124 124 124 PHE PHE L . n 
C 3 125 PRO 125 125 125 PRO PRO L . n 
C 3 126 PRO 126 126 126 PRO PRO L . n 
C 3 127 SER 127 127 127 SER SER L . n 
C 3 128 SER 128 128 128 SER SER L . n 
C 3 129 GLU 129 129 129 GLU GLU L . n 
C 3 130 GLN 130 130 130 GLN GLN L . n 
C 3 131 LEU 131 131 131 LEU LEU L . n 
C 3 132 THR 132 132 132 THR THR L . n 
C 3 133 SER 133 133 133 SER SER L . n 
C 3 134 GLY 134 134 134 GLY GLY L . n 
C 3 135 GLY 135 135 135 GLY GLY L . n 
C 3 136 ALA 136 136 136 ALA ALA L . n 
C 3 137 SER 137 137 137 SER SER L . n 
C 3 138 VAL 138 138 138 VAL VAL L . n 
C 3 139 VAL 139 139 139 VAL VAL L . n 
C 3 140 CYS 140 140 140 CYS CYS L . n 
C 3 141 PHE 141 141 141 PHE PHE L . n 
C 3 142 LEU 142 142 142 LEU LEU L . n 
C 3 143 ASN 143 143 143 ASN ASN L . n 
C 3 144 ASN 144 144 144 ASN ASN L . n 
C 3 145 PHE 145 145 145 PHE PHE L . n 
C 3 146 TYR 146 146 146 TYR TYR L . n 
C 3 147 PRO 147 147 147 PRO PRO L . n 
C 3 148 LYS 148 148 148 LYS LYS L . n 
C 3 149 ASP 149 149 149 ASP ASP L . n 
C 3 150 ILE 150 150 150 ILE ILE L . n 
C 3 151 ASN 151 151 151 ASN ASN L . n 
C 3 152 VAL 152 152 152 VAL VAL L . n 
C 3 153 LYS 153 153 153 LYS LYS L . n 
C 3 154 TRP 154 154 154 TRP TRP L . n 
C 3 155 LYS 155 155 155 LYS LYS L . n 
C 3 156 ILE 156 156 156 ILE ILE L . n 
C 3 157 ASP 157 157 157 ASP ASP L . n 
C 3 158 GLY 158 158 158 GLY GLY L . n 
C 3 159 SER 159 159 159 SER SER L . n 
C 3 160 GLU 160 160 160 GLU GLU L . n 
C 3 161 ARG 161 161 161 ARG ARG L . n 
C 3 162 GLN 162 162 162 GLN GLN L . n 
C 3 163 ASN 163 163 163 ASN ASN L . n 
C 3 164 GLY 164 164 164 GLY GLY L . n 
C 3 165 VAL 165 165 165 VAL VAL L . n 
C 3 166 LEU 166 166 166 LEU LEU L . n 
C 3 167 ASN 167 167 167 ASN ASN L . n 
C 3 168 SER 168 168 168 SER SER L . n 
C 3 169 TRP 169 169 169 TRP TRP L . n 
C 3 170 THR 170 170 170 THR THR L . n 
C 3 171 ASP 171 171 171 ASP ASP L . n 
C 3 172 GLN 172 172 172 GLN GLN L . n 
C 3 173 ASP 173 173 173 ASP ASP L . n 
C 3 174 SER 174 174 174 SER SER L . n 
C 3 175 LYS 175 175 175 LYS LYS L . n 
C 3 176 ASP 176 176 176 ASP ASP L . n 
C 3 177 SER 177 177 177 SER SER L . n 
C 3 178 THR 178 178 178 THR THR L . n 
C 3 179 TYR 179 179 179 TYR TYR L . n 
C 3 180 SER 180 180 180 SER SER L . n 
C 3 181 MET 181 181 181 MET MET L . n 
C 3 182 SER 182 182 182 SER SER L . n 
C 3 183 SER 183 183 183 SER SER L . n 
C 3 184 THR 184 184 184 THR THR L . n 
C 3 185 LEU 185 185 185 LEU LEU L . n 
C 3 186 THR 186 186 186 THR THR L . n 
C 3 187 LEU 187 187 187 LEU LEU L . n 
C 3 188 THR 188 188 188 THR THR L . n 
C 3 189 LYS 189 189 189 LYS LYS L . n 
C 3 190 ASP 190 190 190 ASP ASP L . n 
C 3 191 GLU 191 191 191 GLU GLU L . n 
C 3 192 TYR 192 192 192 TYR TYR L . n 
C 3 193 GLU 193 193 193 GLU GLU L . n 
C 3 194 ARG 194 194 194 ARG ARG L . n 
C 3 195 HIS 195 195 195 HIS HIS L . n 
C 3 196 ASN 196 196 196 ASN ASN L . n 
C 3 197 SER 197 197 197 SER SER L . n 
C 3 198 TYR 198 198 198 TYR TYR L . n 
C 3 199 THR 199 199 199 THR THR L . n 
C 3 200 CYS 200 200 200 CYS CYS L . n 
C 3 201 GLU 201 201 201 GLU GLU L . n 
C 3 202 ALA 202 202 202 ALA ALA L . n 
C 3 203 THR 203 203 203 THR THR L . n 
C 3 204 HIS 204 204 204 HIS HIS L . n 
C 3 205 LYS 205 205 205 LYS LYS L . n 
C 3 206 THR 206 206 206 THR THR L . n 
C 3 207 SER 207 207 207 SER SER L . n 
C 3 208 THR 208 208 208 THR THR L . n 
C 3 209 SER 209 209 209 SER SER L . n 
C 3 210 PRO 210 210 210 PRO PRO L . n 
C 3 211 ILE 211 211 211 ILE ILE L . n 
C 3 212 VAL 212 212 212 VAL VAL L . n 
C 3 213 LYS 213 213 213 LYS LYS L . n 
C 3 214 SER 214 214 214 SER SER L . n 
C 3 215 PHE 215 215 215 PHE PHE L . n 
C 3 216 ASN 216 216 216 ASN ASN L . n 
C 3 217 ARG 217 217 217 ARG ARG L . n 
C 3 218 ASN 218 218 ?   ?   ?   L . n 
C 3 219 GLU 219 219 ?   ?   ?   L . n 
C 3 220 CYS 220 220 ?   ?   ?   L . n 
D 4 1   GLU 1   1   1   GLU GLU H . n 
D 4 2   VAL 2   2   2   VAL VAL H . n 
D 4 3   GLN 3   3   3   GLN GLN H . n 
D 4 4   LEU 4   4   4   LEU LEU H . n 
D 4 5   GLN 5   5   5   GLN GLN H . n 
D 4 6   GLN 6   6   6   GLN GLN H . n 
D 4 7   SER 7   7   7   SER SER H . n 
D 4 8   GLY 8   8   8   GLY GLY H . n 
D 4 9   ALA 9   9   9   ALA ALA H . n 
D 4 10  GLU 10  10  10  GLU GLU H . n 
D 4 11  LEU 11  11  11  LEU LEU H . n 
D 4 12  VAL 12  12  12  VAL VAL H . n 
D 4 13  LYS 13  13  13  LYS LYS H . n 
D 4 14  PRO 14  14  14  PRO PRO H . n 
D 4 15  GLY 15  15  15  GLY GLY H . n 
D 4 16  ALA 16  16  16  ALA ALA H . n 
D 4 17  SER 17  17  17  SER SER H . n 
D 4 18  VAL 18  18  18  VAL VAL H . n 
D 4 19  ASN 19  19  19  ASN ASN H . n 
D 4 20  LEU 20  20  20  LEU LEU H . n 
D 4 21  SER 21  21  21  SER SER H . n 
D 4 22  CYS 22  22  22  CYS CYS H . n 
D 4 23  LYS 23  23  23  LYS LYS H . n 
D 4 24  ALA 24  24  24  ALA ALA H . n 
D 4 25  SER 25  25  25  SER SER H . n 
D 4 26  GLY 26  26  26  GLY GLY H . n 
D 4 27  TYR 27  27  27  TYR TYR H . n 
D 4 28  THR 28  28  28  THR THR H . n 
D 4 29  PHE 29  29  29  PHE PHE H . n 
D 4 30  THR 30  30  30  THR THR H . n 
D 4 31  ASN 31  31  31  ASN ASN H . n 
D 4 32  TYR 32  32  32  TYR TYR H . n 
D 4 33  TRP 33  33  33  TRP TRP H . n 
D 4 34  MET 34  34  34  MET MET H . n 
D 4 35  HIS 35  35  35  HIS HIS H . n 
D 4 36  TRP 36  36  36  TRP TRP H . n 
D 4 37  VAL 37  37  37  VAL VAL H . n 
D 4 38  ARG 38  38  38  ARG ARG H . n 
D 4 39  LEU 39  39  39  LEU LEU H . n 
D 4 40  ARG 40  40  40  ARG ARG H . n 
D 4 41  PRO 41  41  41  PRO PRO H . n 
D 4 42  GLY 42  42  42  GLY GLY H . n 
D 4 43  GLN 43  43  43  GLN GLN H . n 
D 4 44  GLY 44  44  44  GLY GLY H . n 
D 4 45  LEU 45  45  45  LEU LEU H . n 
D 4 46  GLU 46  46  46  GLU GLU H . n 
D 4 47  TRP 47  47  47  TRP TRP H . n 
D 4 48  ILE 48  48  48  ILE ILE H . n 
D 4 49  GLY 49  49  49  GLY GLY H . n 
D 4 50  GLU 50  50  50  GLU GLU H . n 
D 4 51  ILE 51  51  51  ILE ILE H . n 
D 4 52  ASP 52  52  52  ASP ASP H . n 
D 4 53  PRO 53  53  53  PRO PRO H . n 
D 4 54  SER 54  54  54  SER SER H . n 
D 4 55  ASP 55  55  55  ASP ASP H . n 
D 4 56  SER 56  56  56  SER SER H . n 
D 4 57  TYR 57  57  57  TYR TYR H . n 
D 4 58  SER 58  58  58  SER SER H . n 
D 4 59  TYR 59  59  59  TYR TYR H . n 
D 4 60  TYR 60  60  60  TYR TYR H . n 
D 4 61  SER 61  61  61  SER SER H . n 
D 4 62  GLN 62  62  62  GLN GLN H . n 
D 4 63  ASN 63  63  63  ASN ASN H . n 
D 4 64  PHE 64  64  64  PHE PHE H . n 
D 4 65  LYS 65  65  65  LYS LYS H . n 
D 4 66  GLY 66  66  66  GLY GLY H . n 
D 4 67  LYS 67  67  67  LYS LYS H . n 
D 4 68  ALA 68  68  68  ALA ALA H . n 
D 4 69  THR 69  69  69  THR THR H . n 
D 4 70  LEU 70  70  70  LEU LEU H . n 
D 4 71  THR 71  71  71  THR THR H . n 
D 4 72  VAL 72  72  72  VAL VAL H . n 
D 4 73  ASP 73  73  73  ASP ASP H . n 
D 4 74  GLN 74  74  74  GLN GLN H . n 
D 4 75  SER 75  75  75  SER SER H . n 
D 4 76  SER 76  76  76  SER SER H . n 
D 4 77  ASN 77  77  77  ASN ASN H . n 
D 4 78  THR 78  78  78  THR THR H . n 
D 4 79  ALA 79  79  79  ALA ALA H . n 
D 4 80  TYR 80  80  80  TYR TYR H . n 
D 4 81  LEU 81  81  81  LEU LEU H . n 
D 4 82  GLN 82  82  82  GLN GLN H . n 
D 4 83  LEU 83  83  83  LEU LEU H . n 
D 4 84  THR 84  84  84  THR THR H . n 
D 4 85  SER 85  85  85  SER SER H . n 
D 4 86  LEU 86  86  86  LEU LEU H . n 
D 4 87  THR 87  87  87  THR THR H . n 
D 4 88  SER 88  88  88  SER SER H . n 
D 4 89  GLU 89  89  89  GLU GLU H . n 
D 4 90  ASP 90  90  90  ASP ASP H . n 
D 4 91  SER 91  91  91  SER SER H . n 
D 4 92  ALA 92  92  92  ALA ALA H . n 
D 4 93  VAL 93  93  93  VAL VAL H . n 
D 4 94  TYR 94  94  94  TYR TYR H . n 
D 4 95  TYR 95  95  95  TYR TYR H . n 
D 4 96  CYS 96  96  96  CYS CYS H . n 
D 4 97  ALA 97  97  97  ALA ALA H . n 
D 4 98  ARG 98  98  98  ARG ARG H . n 
D 4 99  GLY 99  99  99  GLY GLY H . n 
D 4 100 ARG 100 100 100 ARG ARG H . n 
D 4 101 GLN 101 101 101 GLN GLN H . n 
D 4 102 THR 102 102 102 THR THR H . n 
D 4 103 TYR 103 103 103 TYR TYR H . n 
D 4 104 TYR 104 104 104 TYR TYR H . n 
D 4 105 PRO 105 105 105 PRO PRO H . n 
D 4 106 TRP 106 106 106 TRP TRP H . n 
D 4 107 PHE 107 107 107 PHE PHE H . n 
D 4 108 PRO 108 108 108 PRO PRO H . n 
D 4 109 TYR 109 109 109 TYR TYR H . n 
D 4 110 TRP 110 110 110 TRP TRP H . n 
D 4 111 GLY 111 111 111 GLY GLY H . n 
D 4 112 GLN 112 112 112 GLN GLN H . n 
D 4 113 GLY 113 113 113 GLY GLY H . n 
D 4 114 THR 114 114 114 THR THR H . n 
D 4 115 LEU 115 115 115 LEU LEU H . n 
D 4 116 VAL 116 116 116 VAL VAL H . n 
D 4 117 THR 117 117 117 THR THR H . n 
D 4 118 VAL 118 118 118 VAL VAL H . n 
D 4 119 SER 119 119 119 SER SER H . n 
D 4 120 ALA 120 120 120 ALA ALA H . n 
D 4 121 ALA 121 121 121 ALA ALA H . n 
D 4 122 LYS 122 122 122 LYS LYS H . n 
D 4 123 THR 123 123 123 THR THR H . n 
D 4 124 THR 124 124 124 THR THR H . n 
D 4 125 PRO 125 125 125 PRO PRO H . n 
D 4 126 PRO 126 126 126 PRO PRO H . n 
D 4 127 SER 127 127 127 SER SER H . n 
D 4 128 ASP 128 128 128 ASP ASP H . n 
D 4 129 TYR 129 129 129 TYR TYR H . n 
D 4 130 PRO 130 130 130 PRO PRO H . n 
D 4 131 LEU 131 131 131 LEU LEU H . n 
D 4 132 ALA 132 132 132 ALA ALA H . n 
D 4 133 PRO 133 133 133 PRO PRO H . n 
D 4 134 GLY 134 134 134 GLY GLY H . n 
D 4 135 SER 135 135 135 SER SER H . n 
D 4 136 ALA 136 136 136 ALA ALA H . n 
D 4 137 ALA 137 137 137 ALA ALA H . n 
D 4 138 GLN 138 138 138 GLN GLN H . n 
D 4 139 THR 139 139 139 THR THR H . n 
D 4 140 ASN 140 140 140 ASN ASN H . n 
D 4 141 SER 141 141 141 SER SER H . n 
D 4 142 MET 142 142 142 MET MET H . n 
D 4 143 VAL 143 143 143 VAL VAL H . n 
D 4 144 THR 144 144 144 THR THR H . n 
D 4 145 LEU 145 145 145 LEU LEU H . n 
D 4 146 GLY 146 146 146 GLY GLY H . n 
D 4 147 CYS 147 147 147 CYS CYS H . n 
D 4 148 LEU 148 148 148 LEU LEU H . n 
D 4 149 VAL 149 149 149 VAL VAL H . n 
D 4 150 LYS 150 150 150 LYS LYS H . n 
D 4 151 GLY 151 151 151 GLY GLY H . n 
D 4 152 TYR 152 152 152 TYR TYR H . n 
D 4 153 PHE 153 153 153 PHE PHE H . n 
D 4 154 PRO 154 154 154 PRO PRO H . n 
D 4 155 GLU 155 155 155 GLU GLU H . n 
D 4 156 PRO 156 156 156 PRO PRO H . n 
D 4 157 VAL 157 157 157 VAL VAL H . n 
D 4 158 THR 158 158 158 THR THR H . n 
D 4 159 VAL 159 159 159 VAL VAL H . n 
D 4 160 THR 160 160 160 THR THR H . n 
D 4 161 TRP 161 161 161 TRP TRP H . n 
D 4 162 ASN 162 162 162 ASN ASN H . n 
D 4 163 SER 163 163 163 SER SER H . n 
D 4 164 GLY 164 164 164 GLY GLY H . n 
D 4 165 SER 165 165 165 SER SER H . n 
D 4 166 LEU 166 166 166 LEU LEU H . n 
D 4 167 SER 167 167 167 SER SER H . n 
D 4 168 SER 168 168 168 SER SER H . n 
D 4 169 GLY 169 169 169 GLY GLY H . n 
D 4 170 VAL 170 170 170 VAL VAL H . n 
D 4 171 HIS 171 171 171 HIS HIS H . n 
D 4 172 THR 172 172 172 THR THR H . n 
D 4 173 PHE 173 173 173 PHE PHE H . n 
D 4 174 PRO 174 174 174 PRO PRO H . n 
D 4 175 ALA 175 175 175 ALA ALA H . n 
D 4 176 VAL 176 176 176 VAL VAL H . n 
D 4 177 LEU 177 177 177 LEU LEU H . n 
D 4 178 GLN 178 178 178 GLN GLN H . n 
D 4 179 SER 179 179 179 SER SER H . n 
D 4 180 ASP 180 180 180 ASP ASP H . n 
D 4 181 LEU 181 181 181 LEU LEU H . n 
D 4 182 TYR 182 182 182 TYR TYR H . n 
D 4 183 THR 183 183 183 THR THR H . n 
D 4 184 LEU 184 184 184 LEU LEU H . n 
D 4 185 SER 185 185 185 SER SER H . n 
D 4 186 SER 186 186 186 SER SER H . n 
D 4 187 SER 187 187 187 SER SER H . n 
D 4 188 VAL 188 188 188 VAL VAL H . n 
D 4 189 THR 189 189 189 THR THR H . n 
D 4 190 VAL 190 190 190 VAL VAL H . n 
D 4 191 PRO 191 191 191 PRO PRO H . n 
D 4 192 SER 192 192 192 SER SER H . n 
D 4 193 SER 193 193 193 SER SER H . n 
D 4 194 THR 194 194 194 THR THR H . n 
D 4 195 TRP 195 195 195 TRP TRP H . n 
D 4 196 PRO 196 196 196 PRO PRO H . n 
D 4 197 SER 197 197 197 SER SER H . n 
D 4 198 GLU 198 198 198 GLU GLU H . n 
D 4 199 THR 199 199 199 THR THR H . n 
D 4 200 VAL 200 200 200 VAL VAL H . n 
D 4 201 THR 201 201 201 THR THR H . n 
D 4 202 CYS 202 202 202 CYS CYS H . n 
D 4 203 ASN 203 203 203 ASN ASN H . n 
D 4 204 VAL 204 204 204 VAL VAL H . n 
D 4 205 ALA 205 205 205 ALA ALA H . n 
D 4 206 HIS 206 206 206 HIS HIS H . n 
D 4 207 PRO 207 207 207 PRO PRO H . n 
D 4 208 ALA 208 208 208 ALA ALA H . n 
D 4 209 SER 209 209 209 SER SER H . n 
D 4 210 SER 210 210 210 SER SER H . n 
D 4 211 THR 211 211 211 THR THR H . n 
D 4 212 LYS 212 212 212 LYS LYS H . n 
D 4 213 VAL 213 213 213 VAL VAL H . n 
D 4 214 ASP 214 214 214 ASP ASP H . n 
D 4 215 LYS 215 215 215 LYS LYS H . n 
D 4 216 LYS 216 216 216 LYS LYS H . n 
D 4 217 ILE 217 217 217 ILE ILE H . n 
D 4 218 VAL 218 218 218 VAL VAL H . n 
D 4 219 PRO 219 219 219 PRO PRO H . n 
D 4 220 ARG 220 220 220 ARG ARG H . n 
D 4 221 ASP 221 221 ?   ?   ?   H . n 
D 4 222 CYS 222 222 ?   ?   ?   H . n 
D 4 223 GLY 223 223 ?   ?   ?   H . n 
D 4 224 CYS 224 224 ?   ?   ?   H . n 
D 4 225 LYS 225 225 ?   ?   ?   H . n 
D 4 226 PRO 226 226 ?   ?   ?   H . n 
D 4 227 CYS 227 227 ?   ?   ?   H . n 
D 4 228 ILE 228 228 ?   ?   ?   H . n 
D 4 229 CYS 229 229 ?   ?   ?   H . n 
D 4 230 THR 230 230 ?   ?   ?   H . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 5 NAG 1 701 631 NAG NAG A . 
F 5 NAG 1 702 632 NAG NAG A . 
G 5 NAG 1 703 634 NAG NAG A . 
H 5 NAG 1 704 635 NAG NAG A . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8KDI 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8KDI 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8KDI 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               209.676 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.952 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  'HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8KDI 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.58 
_refine.ls_d_res_low                             3.58 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     87173 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    100.00 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.25546 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.25546 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'PARAMETERS FOR MASK CACLULATION' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD WITH PHASES' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.445 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             11.904 
_refine.overall_SU_ML                            0.172 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'ELECTRON MICROSCOPY' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       . 
_refine_hist.d_res_low                        . 
_refine_hist.number_atoms_solvent             ? 
_refine_hist.number_atoms_total               10532 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        ? 
_refine_hist.pdbx_number_atoms_nucleic_acid   ? 
_refine_hist.pdbx_number_atoms_ligand         ? 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.012  0.012  10806 ? r_bond_refined_d             ? ? 
'ELECTRON MICROSCOPY' ? 0.000  0.016  10224 ? r_bond_other_d               ? ? 
'ELECTRON MICROSCOPY' ? 2.028  1.643  14736 ? r_angle_refined_deg          ? ? 
'ELECTRON MICROSCOPY' ? 0.712  1.567  23574 ? r_angle_other_deg            ? ? 
'ELECTRON MICROSCOPY' ? 8.568  5.000  1348  ? r_dihedral_angle_1_deg       ? ? 
'ELECTRON MICROSCOPY' ? 8.696  5.000  42    ? r_dihedral_angle_2_deg       ? ? 
'ELECTRON MICROSCOPY' ? 14.602 10.000 1739  ? r_dihedral_angle_3_deg       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_dihedral_angle_4_deg       ? ? 
'ELECTRON MICROSCOPY' ? 0.083  0.200  1700  ? r_chiral_restr               ? ? 
'ELECTRON MICROSCOPY' ? 0.004  0.020  12541 ? r_gen_planes_refined         ? ? 
'ELECTRON MICROSCOPY' ? 0.001  0.020  2449  ? r_gen_planes_other           ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'ELECTRON MICROSCOPY' ? 32.384 18.772 5407  ? r_mcbond_it                  ? ? 
'ELECTRON MICROSCOPY' ? 32.370 18.772 5407  ? r_mcbond_other               ? ? 
'ELECTRON MICROSCOPY' ? 46.204 33.920 6750  ? r_mcangle_it                 ? ? 
'ELECTRON MICROSCOPY' ? 46.200 33.922 6751  ? r_mcangle_other              ? ? 
'ELECTRON MICROSCOPY' ? 39.815 22.276 5399  ? r_scbond_it                  ? ? 
'ELECTRON MICROSCOPY' ? 39.812 22.279 5400  ? r_scbond_other               ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'ELECTRON MICROSCOPY' ? 60.515 39.283 7987  ? r_scangle_other              ? ? 
'ELECTRON MICROSCOPY' ? 68.075 230.04 42609 ? r_long_range_B_refined       ? ? 
'ELECTRON MICROSCOPY' ? 68.074 230.04 42610 ? r_long_range_B_other         ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'ELECTRON MICROSCOPY' 
_refine_ls_shell.d_res_high                       3.600 
_refine_ls_shell.d_res_low                        3.694 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             0 
_refine_ls_shell.number_reflns_R_work             6470 
_refine_ls_shell.percent_reflns_obs               100.00 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  1.646 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.000 
# 
_struct.entry_id                     8KDI 
_struct.title                        'Structure of apo inward-open LAT1-CD98hc-Fab170 in nanodisc, consensus map' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8KDI 
_struct_keywords.text            
'Transporter, Amino acid, Glycoprotein, Cancer, TRANSPORT PROTEIN, TRANSPORT PROTEIN-IMMUNE SYSTEM complex' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN/IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 5 ? 
G N N 5 ? 
H N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP 4F2_HUMAN  P08195 ? 1 
;ELQPPEASIAVVSIPRQLPGSHSEAGVQGLSAGDDSELGSHCVAQTGLELLASGDPLPSASQNAEMIETGSDCVTQAGLQ
LLASSDPPALASKNAEVTGTMSQDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEKNGLVKIKVAEDEAEAAAAAKF
TGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAGNL
AGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWFST
QVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQILSLLESNKDLLLT
SSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAALPG
QPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQNE
RFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPYAA
;
2 
2 UNP LAT1_HUMAN Q01650 ? 2 
;MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAG
SPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPL
FPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV
GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHL
GVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFF
SFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN
KPKWLLQGIFSTTVLCQKLMQVVPQET
;
1 
3 PDB 8KDI       8KDI   ? 3 ? 1 
4 PDB 8KDI       8KDI   ? 4 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8KDI A 3 ? 631 ? P08195 2 ? 630 ? 2 630 
2 2 8KDI B 1 ? 507 ? Q01650 1 ? 507 ? 1 507 
3 3 8KDI L 1 ? 220 ? 8KDI   1 ? 220 ? 1 220 
4 4 8KDI H 1 ? 230 ? 8KDI   1 ? 230 ? 1 230 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8KDI GLY A 1   ? UNP P08195 ? ? 'expression tag' 0   1  
1 8KDI SER A 2   ? UNP P08195 ? ? 'expression tag' 1   2  
2 8KDI ASP B 508 ? UNP Q01650 ? ? 'expression tag' 508 3  
2 8KDI TYR B 509 ? UNP Q01650 ? ? 'expression tag' 509 4  
2 8KDI LYS B 510 ? UNP Q01650 ? ? 'expression tag' 510 5  
2 8KDI ASP B 511 ? UNP Q01650 ? ? 'expression tag' 511 6  
2 8KDI ASP B 512 ? UNP Q01650 ? ? 'expression tag' 512 7  
2 8KDI ASP B 513 ? UNP Q01650 ? ? 'expression tag' 513 8  
2 8KDI ASP B 514 ? UNP Q01650 ? ? 'expression tag' 514 9  
2 8KDI LYS B 515 ? UNP Q01650 ? ? 'expression tag' 515 10 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 166 ? ALA A 174 ? SER A 165 ALA A 173 1 ? 9  
HELX_P HELX_P2  AA2 GLY A 178 ? ALA A 208 ? GLY A 177 ALA A 207 1 ? 31 
HELX_P HELX_P3  AA3 LYS A 218 ? GLY A 223 ? LYS A 217 GLY A 222 5 ? 6  
HELX_P HELX_P4  AA4 ASN A 241 ? LYS A 256 ? ASN A 240 LYS A 255 1 ? 16 
HELX_P HELX_P5  AA5 ASP A 282 ? GLY A 286 ? ASP A 281 GLY A 285 5 ? 5  
HELX_P HELX_P6  AA6 SER A 287 ? LYS A 301 ? SER A 286 LYS A 300 1 ? 15 
HELX_P HELX_P7  AA7 GLN A 323 ? GLY A 342 ? GLN A 322 GLY A 341 1 ? 20 
HELX_P HELX_P8  AA8 ASP A 350 ? LEU A 354 ? ASP A 349 LEU A 353 5 ? 5  
HELX_P HELX_P9  AA9 ASP A 356 ? SER A 372 ? ASP A 355 SER A 371 1 ? 17 
HELX_P HELX_P10 AB1 ASP A 385 ? ASN A 396 ? ASP A 384 ASN A 395 1 ? 12 
HELX_P HELX_P11 AB2 SER A 404 ? ASP A 408 ? SER A 403 ASP A 407 5 ? 5  
HELX_P HELX_P12 AB3 HIS A 415 ? GLY A 428 ? HIS A 414 GLY A 427 1 ? 14 
HELX_P HELX_P13 AB4 LEU A 441 ? PHE A 445 ? LEU A 440 PHE A 444 5 ? 5  
HELX_P HELX_P14 AB5 LEU A 450 ? PHE A 459 ? LEU A 449 PHE A 458 1 ? 10 
HELX_P HELX_P15 AB6 GLY A 470 ? GLY A 474 ? GLY A 469 GLY A 473 5 ? 5  
HELX_P HELX_P16 AB7 SER A 505 ? MET A 508 ? SER A 504 MET A 507 5 ? 4  
HELX_P HELX_P17 AB8 THR A 509 ? GLU A 515 ? THR A 508 GLU A 514 1 ? 7  
HELX_P HELX_P18 AB9 SER A 519 ? GLU A 534 ? SER A 518 GLU A 533 1 ? 16 
HELX_P HELX_P19 AC1 GLU A 534 ? GLY A 540 ? GLU A 533 GLY A 539 1 ? 7  
HELX_P HELX_P20 AC2 GLU A 613 ? LEU A 615 ? GLU A 612 LEU A 614 5 ? 3  
HELX_P HELX_P21 AC3 LEU B 52  ? ILE B 64  ? LEU B 52  ILE B 64  1 ? 13 
HELX_P HELX_P22 AC4 SER B 66  ? VAL B 70  ? SER B 66  VAL B 70  5 ? 5  
HELX_P HELX_P23 AC5 THR B 71  ? GLY B 80  ? THR B 71  GLY B 80  1 ? 10 
HELX_P HELX_P24 AC6 SER B 81  ? ILE B 110 ? SER B 81  ILE B 110 1 ? 30 
HELX_P HELX_P25 AC7 GLY B 115 ? TYR B 124 ? GLY B 115 TYR B 124 1 ? 10 
HELX_P HELX_P26 AC8 GLY B 125 ? ILE B 139 ? GLY B 125 ILE B 139 1 ? 15 
HELX_P HELX_P27 AC9 ILE B 139 ? LYS B 158 ? ILE B 139 LYS B 158 1 ? 20 
HELX_P HELX_P28 AD1 PRO B 159 ? PHE B 161 ? PRO B 159 PHE B 161 5 ? 3  
HELX_P HELX_P29 AD2 PRO B 167 ? SER B 189 ? PRO B 167 SER B 189 1 ? 23 
HELX_P HELX_P30 AD3 SER B 189 ? GLY B 222 ? SER B 189 GLY B 222 1 ? 34 
HELX_P HELX_P31 AD4 ASP B 239 ? TYR B 254 ? ASP B 239 TYR B 254 1 ? 16 
HELX_P HELX_P32 AD5 GLY B 256 ? ASN B 261 ? GLY B 256 ASN B 261 1 ? 6  
HELX_P HELX_P33 AD6 PHE B 262 ? MET B 267 ? PHE B 262 MET B 267 5 ? 6  
HELX_P HELX_P34 AD7 ARG B 272 ? THR B 298 ? ARG B 272 THR B 298 1 ? 27 
HELX_P HELX_P35 AD8 SER B 301 ? LEU B 306 ? SER B 301 LEU B 306 1 ? 6  
HELX_P HELX_P36 AD9 ALA B 310 ? LEU B 320 ? ALA B 310 LEU B 320 1 ? 11 
HELX_P HELX_P37 AE1 VAL B 322 ? TRP B 325 ? VAL B 322 TRP B 325 5 ? 4  
HELX_P HELX_P38 AE2 ILE B 326 ? THR B 345 ? ILE B 326 THR B 345 1 ? 20 
HELX_P HELX_P39 AE3 SER B 346 ? GLU B 356 ? SER B 346 GLU B 356 1 ? 11 
HELX_P HELX_P40 AE4 PRO B 360 ? MET B 365 ? PRO B 360 MET B 365 5 ? 6  
HELX_P HELX_P41 AE5 PRO B 373 ? TYR B 387 ? PRO B 373 TYR B 387 1 ? 15 
HELX_P HELX_P42 AE6 ALA B 388 ? SER B 390 ? ALA B 388 SER B 390 5 ? 3  
HELX_P HELX_P43 AE7 ASP B 392 ? LYS B 422 ? ASP B 392 LYS B 422 1 ? 31 
HELX_P HELX_P44 AE8 LEU B 435 ? THR B 454 ? LEU B 435 THR B 454 1 ? 20 
HELX_P HELX_P45 AE9 THR B 454 ? SER B 467 ? THR B 454 SER B 467 1 ? 14 
HELX_P HELX_P46 AF1 SER B 467 ? VAL B 476 ? SER B 467 VAL B 476 1 ? 10 
HELX_P HELX_P47 AF2 PRO B 482 ? GLN B 501 ? PRO B 482 GLN B 501 1 ? 20 
HELX_P HELX_P48 AF3 GLN C 85  ? LEU C 89  ? GLN L 85  LEU L 89  5 ? 5  
HELX_P HELX_P49 AF4 GLU C 129 ? SER C 133 ? GLU L 129 SER L 133 5 ? 5  
HELX_P HELX_P50 AF5 LYS C 189 ? ARG C 194 ? LYS L 189 ARG L 194 1 ? 6  
HELX_P HELX_P51 AF6 THR D 28  ? TYR D 32  ? THR H 28  TYR H 32  5 ? 5  
HELX_P HELX_P52 AF7 GLN D 62  ? LYS D 65  ? GLN H 62  LYS H 65  5 ? 4  
HELX_P HELX_P53 AF8 THR D 87  ? SER D 91  ? THR H 87  SER H 91  5 ? 5  
HELX_P HELX_P54 AF9 ALA D 136 ? ASN D 140 ? ALA H 136 ASN H 140 5 ? 5  
HELX_P HELX_P55 AG1 THR D 194 ? GLU D 198 ? THR H 194 GLU H 198 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?   ? A CYS 211 SG  ? ? ? 1_555 B CYS 164 SG ? ? A CYS 210 B CYS 164 1_555 ? ? ? ? ? ? ? 2.116 ? ?               
disulf2 disulf ?   ? C CYS 23  SG  ? ? ? 1_555 C CYS 94  SG ? ? L CYS 23  L CYS 94  1_555 ? ? ? ? ? ? ? 2.119 ? ?               
disulf3 disulf ?   ? C CYS 140 SG  ? ? ? 1_555 C CYS 200 SG ? ? L CYS 140 L CYS 200 1_555 ? ? ? ? ? ? ? 2.048 ? ?               
disulf4 disulf ?   ? D CYS 22  SG  ? ? ? 1_555 D CYS 96  SG ? ? H CYS 22  H CYS 96  1_555 ? ? ? ? ? ? ? 2.113 ? ?               
disulf5 disulf ?   ? D CYS 147 SG  ? ? ? 1_555 D CYS 202 SG ? ? H CYS 147 H CYS 202 1_555 ? ? ? ? ? ? ? 2.071 ? ?               
covale1 covale one ? A ASN 366 ND2 ? ? ? 1_555 G NAG .   C1 ? ? A ASN 365 A NAG 703 1_555 ? ? ? ? ? ? ? 1.436 ? N-Glycosylation 
covale2 covale one ? A ASN 382 ND2 ? ? ? 1_555 E NAG .   C1 ? ? A ASN 381 A NAG 701 1_555 ? ? ? ? ? ? ? 1.444 ? N-Glycosylation 
covale3 covale one ? A ASN 425 ND2 ? ? ? 1_555 H NAG .   C1 ? ? A ASN 424 A NAG 704 1_555 ? ? ? ? ? ? ? 1.443 ? N-Glycosylation 
covale4 covale one ? A ASN 507 ND2 ? ? ? 1_555 F NAG .   C1 ? ? A ASN 506 A NAG 702 1_555 ? ? ? ? ? ? ? 1.462 ? N-Glycosylation 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 NAG E .   ? ASN A 382 ? NAG A 701 ? 1_555 ASN A 381 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2 NAG F .   ? ASN A 507 ? NAG A 702 ? 1_555 ASN A 506 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3 NAG G .   ? ASN A 366 ? NAG A 703 ? 1_555 ASN A 365 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4 NAG H .   ? ASN A 425 ? NAG A 704 ? 1_555 ASN A 424 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5 CYS A 211 ? CYS B 164 ? CYS A 210 ? 1_555 CYS B 164 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
6 CYS C 23  ? CYS C 94  ? CYS L 23  ? 1_555 CYS L 94  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
7 CYS C 140 ? CYS C 200 ? CYS L 140 ? 1_555 CYS L 200 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
8 CYS D 22  ? CYS D 96  ? CYS H 22  ? 1_555 CYS H 96  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
9 CYS D 147 ? CYS D 202 ? CYS H 147 ? 1_555 CYS H 202 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 SER 7   C . ? SER 7   L PRO 8   C ? PRO 8   L 1 -10.66 
2 ILE 100 C . ? ILE 100 L PRO 101 C ? PRO 101 L 1 7.30   
3 TYR 146 C . ? TYR 146 L PRO 147 C ? PRO 147 L 1 -4.91  
4 PHE 153 D . ? PHE 153 H PRO 154 D ? PRO 154 H 1 -8.28  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 6 ? 
AA3 ? 2 ? 
AA4 ? 4 ? 
AA5 ? 6 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 6 ? 
AB2 ? 4 ? 
AB3 ? 4 ? 
AB4 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA1 6 7 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? parallel      
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA6 1 2 ? parallel      
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
AB2 1 2 ? parallel      
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LEU A 400 ? THR A 402 ? LEU A 399 THR A 401 
AA1 2 LEU A 376 ? GLY A 380 ? LEU A 375 GLY A 379 
AA1 3 GLY A 345 ? VAL A 348 ? GLY A 344 VAL A 347 
AA1 4 ILE A 306 ? ASP A 308 ? ILE A 305 ASP A 307 
AA1 5 VAL A 261 ? LEU A 262 ? VAL A 260 LEU A 261 
AA1 6 LEU A 225 ? ILE A 228 ? LEU A 224 ILE A 227 
AA1 7 VAL A 466 ? SER A 468 ? VAL A 465 SER A 467 
AA2 1 ASP A 541 ? PHE A 545 ? ASP A 540 PHE A 544 
AA2 2 PHE A 552 ? HIS A 557 ? PHE A 551 HIS A 556 
AA2 3 ARG A 563 ? LEU A 568 ? ARG A 562 LEU A 567 
AA2 4 LEU A 623 ? PHE A 627 ? LEU A 622 PHE A 626 
AA2 5 LYS A 593 ? SER A 599 ? LYS A 592 SER A 598 
AA2 6 PRO A 609 ? GLU A 611 ? PRO A 608 GLU A 610 
AA3 1 GLY A 574 ? LEU A 575 ? GLY A 573 LEU A 574 
AA3 2 THR C 99  ? ILE C 100 ? THR L 99  ILE L 100 
AA4 1 LEU C 4   ? SER C 7   ? LEU L 4   SER L 7   
AA4 2 VAL C 19  ? SER C 25  ? VAL L 19  SER L 25  
AA4 3 ASP C 76  ? ILE C 81  ? ASP L 76  ILE L 81  
AA4 4 PHE C 68  ? SER C 73  ? PHE L 68  SER L 73  
AA5 1 SER C 10  ? SER C 14  ? SER L 10  SER L 14  
AA5 2 THR C 108 ? LYS C 113 ? THR L 108 LYS L 113 
AA5 3 ALA C 90  ? GLN C 96  ? ALA L 90  GLN L 96  
AA5 4 LEU C 39  ? GLN C 44  ? LEU L 39  GLN L 44  
AA5 5 LYS C 51  ? TYR C 55  ? LYS L 51  TYR L 55  
AA5 6 THR C 59  ? ARG C 60  ? THR L 59  ARG L 60  
AA6 1 SER C 10  ? SER C 14  ? SER L 10  SER L 14  
AA6 2 THR C 108 ? LYS C 113 ? THR L 108 LYS L 113 
AA6 3 ALA C 90  ? GLN C 96  ? ALA L 90  GLN L 96  
AA6 4 THR C 103 ? PHE C 104 ? THR L 103 PHE L 104 
AA7 1 THR C 120 ? PHE C 124 ? THR L 120 PHE L 124 
AA7 2 GLY C 135 ? PHE C 145 ? GLY L 135 PHE L 145 
AA7 3 TYR C 179 ? THR C 188 ? TYR L 179 THR L 188 
AA7 4 VAL C 165 ? TRP C 169 ? VAL L 165 TRP L 169 
AA8 1 SER C 159 ? ARG C 161 ? SER L 159 ARG L 161 
AA8 2 ILE C 150 ? ILE C 156 ? ILE L 150 ILE L 156 
AA8 3 SER C 197 ? HIS C 204 ? SER L 197 HIS L 204 
AA8 4 ILE C 211 ? ASN C 216 ? ILE L 211 ASN L 216 
AA9 1 GLN D 3   ? GLN D 6   ? GLN H 3   GLN H 6   
AA9 2 VAL D 18  ? SER D 25  ? VAL H 18  SER H 25  
AA9 3 THR D 78  ? LEU D 83  ? THR H 78  LEU H 83  
AA9 4 ALA D 68  ? ASP D 73  ? ALA H 68  ASP H 73  
AB1 1 ALA D 9   ? VAL D 12  ? ALA H 9   VAL H 12  
AB1 2 THR D 114 ? VAL D 118 ? THR H 114 VAL H 118 
AB1 3 ALA D 92  ? ARG D 98  ? ALA H 92  ARG H 98  
AB1 4 MET D 34  ? LEU D 39  ? MET H 34  LEU H 39  
AB1 5 LEU D 45  ? ILE D 51  ? LEU H 45  ILE H 51  
AB1 6 SER D 58  ? TYR D 60  ? SER H 58  TYR H 60  
AB2 1 ALA D 9   ? VAL D 12  ? ALA H 9   VAL H 12  
AB2 2 THR D 114 ? VAL D 118 ? THR H 114 VAL H 118 
AB2 3 ALA D 92  ? ARG D 98  ? ALA H 92  ARG H 98  
AB2 4 TYR D 109 ? TRP D 110 ? TYR H 109 TRP H 110 
AB3 1 SER D 127 ? LEU D 131 ? SER H 127 LEU H 131 
AB3 2 MET D 142 ? TYR D 152 ? MET H 142 TYR H 152 
AB3 3 LEU D 181 ? PRO D 191 ? LEU H 181 PRO H 191 
AB3 4 VAL D 170 ? GLN D 178 ? VAL H 170 GLN H 178 
AB4 1 THR D 201 ? ALA D 205 ? THR H 201 ALA H 205 
AB4 2 LYS D 212 ? LYS D 216 ? LYS H 212 LYS H 216 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O LEU A 400 ? O LEU A 399 N ALA A 379 ? N ALA A 378 
AA1 2 3 O ILE A 378 ? O ILE A 377 N PHE A 346 ? N PHE A 345 
AA1 3 4 O GLY A 345 ? O GLY A 344 N LEU A 307 ? N LEU A 306 
AA1 4 5 O ILE A 306 ? O ILE A 305 N LEU A 262 ? N LEU A 261 
AA1 5 6 O VAL A 261 ? O VAL A 260 N ILE A 228 ? N ILE A 227 
AA1 6 7 N ARG A 227 ? N ARG A 226 O PHE A 467 ? O PHE A 466 
AA2 1 2 N ASP A 541 ? N ASP A 540 O HIS A 557 ? O HIS A 556 
AA2 2 3 N ARG A 556 ? N ARG A 555 O PHE A 564 ? O PHE A 563 
AA2 3 4 N ARG A 563 ? N ARG A 562 O PHE A 627 ? O PHE A 626 
AA2 4 5 O LEU A 624 ? O LEU A 623 N LEU A 598 ? N LEU A 597 
AA2 5 6 N ALA A 594 ? N ALA A 593 O LEU A 610 ? O LEU A 609 
AA3 1 2 N GLY A 574 ? N GLY A 573 O ILE C 100 ? O ILE L 100 
AA4 1 2 N THR C 5   ? N THR L 5   O LYS C 24  ? O LYS L 24  
AA4 2 3 N MET C 21  ? N MET L 21  O LEU C 79  ? O LEU L 79  
AA4 3 4 O THR C 78  ? O THR L 78  N SER C 71  ? N SER L 71  
AA5 1 2 N MET C 13  ? N MET L 13  O GLU C 111 ? O GLU L 111 
AA5 2 3 O LEU C 110 ? O LEU L 110 N ALA C 90  ? N ALA L 90  
AA5 3 4 O LEU C 91  ? O LEU L 91  N GLN C 44  ? N GLN L 44  
AA5 4 5 N TRP C 41  ? N TRP L 41  O LEU C 53  ? O LEU L 53  
AA5 5 6 N TYR C 55  ? N TYR L 55  O THR C 59  ? O THR L 59  
AA6 1 2 N MET C 13  ? N MET L 13  O GLU C 111 ? O GLU L 111 
AA6 2 3 O LEU C 110 ? O LEU L 110 N ALA C 90  ? N ALA L 90  
AA6 3 4 N GLN C 96  ? N GLN L 96  O THR C 103 ? O THR L 103 
AA7 1 2 N THR C 120 ? N THR L 120 O ASN C 143 ? O ASN L 143 
AA7 2 3 N LEU C 142 ? N LEU L 142 O MET C 181 ? O MET L 181 
AA7 3 4 O THR C 184 ? O THR L 184 N LEU C 166 ? N LEU L 166 
AA8 1 2 O ARG C 161 ? O ARG L 161 N TRP C 154 ? N TRP L 154 
AA8 2 3 N LYS C 153 ? N LYS L 153 O GLU C 201 ? O GLU L 201 
AA8 3 4 N TYR C 198 ? N TYR L 198 O PHE C 215 ? O PHE L 215 
AA9 1 2 N GLN D 5   ? N GLN H 5   O LYS D 23  ? O LYS H 23  
AA9 2 3 N LEU D 20  ? N LEU H 20  O LEU D 81  ? O LEU H 81  
AA9 3 4 O GLN D 82  ? O GLN H 82  N THR D 69  ? N THR H 69  
AB1 1 2 N GLU D 10  ? N GLU H 10  O THR D 117 ? O THR H 117 
AB1 2 3 O THR D 114 ? O THR H 114 N TYR D 94  ? N TYR H 94  
AB1 3 4 O TYR D 95  ? O TYR H 95  N VAL D 37  ? N VAL H 37  
AB1 4 5 N TRP D 36  ? N TRP H 36  O ILE D 48  ? O ILE H 48  
AB1 5 6 N GLU D 50  ? N GLU H 50  O TYR D 59  ? O TYR H 59  
AB2 1 2 N GLU D 10  ? N GLU H 10  O THR D 117 ? O THR H 117 
AB2 2 3 O THR D 114 ? O THR H 114 N TYR D 94  ? N TYR H 94  
AB2 3 4 N ARG D 98  ? N ARG H 98  O TYR D 109 ? O TYR H 109 
AB3 1 2 N TYR D 129 ? N TYR H 129 O LEU D 148 ? O LEU H 148 
AB3 2 3 N TYR D 152 ? N TYR H 152 O TYR D 182 ? O TYR H 182 
AB3 3 4 O LEU D 181 ? O LEU H 181 N GLN D 178 ? N GLN H 178 
AB4 1 2 N VAL D 204 ? N VAL H 204 O VAL D 213 ? O VAL H 213 
# 
_pdbx_entry_details.entry_id                   8KDI 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   CB 
_pdbx_validate_close_contact.auth_asym_id_1   A 
_pdbx_validate_close_contact.auth_comp_id_1   LYS 
_pdbx_validate_close_contact.auth_seq_id_1    532 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   OE1 
_pdbx_validate_close_contact.auth_asym_id_2   B 
_pdbx_validate_close_contact.auth_comp_id_2   GLU 
_pdbx_validate_close_contact.auth_seq_id_2    303 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.07 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 CA A LEU 213 ? ? C   A LEU 213 ? ? O   A LEU 213 ? ? 132.87 120.10 12.77  2.10 N 
2  1 O  A LEU 213 ? ? C   A LEU 213 ? ? N   A PRO 214 ? ? 99.57  121.10 -21.53 1.90 Y 
3  1 CA A PRO 214 ? ? N   A PRO 214 ? ? CD  A PRO 214 ? ? 120.70 111.70 9.00   1.40 N 
4  1 N  A PRO 214 ? ? CA  A PRO 214 ? ? CB  A PRO 214 ? ? 95.93  103.30 -7.37  1.20 N 
5  1 NE A ARG 348 ? ? CZ  A ARG 348 ? ? NH1 A ARG 348 ? ? 116.47 120.30 -3.83  0.50 N 
6  1 NE A ARG 348 ? ? CZ  A ARG 348 ? ? NH2 A ARG 348 ? ? 124.03 120.30 3.73   0.50 N 
7  1 NE A ARG 429 ? ? CZ  A ARG 429 ? ? NH2 A ARG 429 ? ? 124.30 120.30 4.00   0.50 N 
8  1 NE A ARG 451 ? ? CZ  A ARG 451 ? ? NH1 A ARG 451 ? ? 116.46 120.30 -3.84  0.50 N 
9  1 CB A TYR 553 ? ? CG  A TYR 553 ? ? CD1 A TYR 553 ? ? 116.76 121.00 -4.24  0.60 N 
10 1 NE A ARG 555 ? ? CZ  A ARG 555 ? ? NH2 A ARG 555 ? ? 124.05 120.30 3.75   0.50 N 
11 1 CA A VAL 572 ? ? CB  A VAL 572 ? ? CG1 A VAL 572 ? ? 101.54 110.90 -9.36  1.50 N 
12 1 CB B TYR 289 ? ? CG  B TYR 289 ? ? CD2 B TYR 289 ? ? 116.79 121.00 -4.21  0.60 N 
13 1 CB B TYR 289 ? ? CG  B TYR 289 ? ? CD1 B TYR 289 ? ? 124.73 121.00 3.73   0.60 N 
14 1 NE H ARG 38  ? ? CZ  H ARG 38  ? ? NH1 H ARG 38  ? ? 117.19 120.30 -3.11  0.50 N 
15 1 N  H TYR 103 ? ? CA  H TYR 103 ? ? CB  H TYR 103 ? ? 123.22 110.60 12.62  1.80 N 
16 1 CA H TYR 103 ? ? CB  H TYR 103 ? ? CG  H TYR 103 ? ? 125.24 113.40 11.84  1.90 N 
17 1 CG H TYR 103 ? ? CD2 H TYR 103 ? ? CE2 H TYR 103 ? ? 126.61 121.30 5.31   0.80 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 TYR A 225 ? ? -165.98 117.47  
2  1 LYS A 257 ? ? -75.92  28.08   
3  1 ASP A 270 ? ? 59.70   10.30   
4  1 ASN A 311 ? ? -95.46  49.13   
5  1 PHE A 319 ? ? 62.74   163.19  
6  1 ASP A 373 ? ? -97.55  42.31   
7  1 SER A 410 ? ? 55.80   15.72   
8  1 ARG A 429 ? ? -69.46  -172.29 
9  1 ALA A 438 ? ? -146.49 -48.43  
10 1 PHE A 444 ? ? -131.67 -48.08  
11 1 ALA A 486 ? ? -160.12 68.65   
12 1 HIS A 538 ? ? -162.79 21.15   
13 1 ALA A 576 ? ? -152.22 27.94   
14 1 SER B 111 ? ? 59.82   0.42    
15 1 TYR B 124 ? ? -134.77 -38.92  
16 1 SER B 126 ? ? 51.85   -125.12 
17 1 SER B 189 ? ? -165.07 110.99  
18 1 LEU B 238 ? ? -142.36 23.32   
19 1 LEU B 260 ? ? -142.98 -2.70   
20 1 ILE B 326 ? ? -117.18 -86.96  
21 1 VAL B 476 ? ? -134.47 -53.46  
22 1 SER L 26  ? ? -69.60  1.77    
23 1 LEU L 53  ? ? -99.68  -66.19  
24 1 THR L 57  ? ? 65.58   -31.32  
25 1 ASN L 144 ? ? 62.51   68.90   
26 1 ASP H 55  ? ? -156.58 8.99    
27 1 THR H 69  ? ? -167.00 110.58  
28 1 ALA H 92  ? ? -174.95 -178.94 
29 1 TYR H 103 ? ? 90.71   -19.77  
30 1 PRO H 154 ? ? -78.14  -169.44 
31 1 LEU H 166 ? ? -90.02  58.07   
# 
loop_
_pdbx_validate_peptide_omega.id 
_pdbx_validate_peptide_omega.PDB_model_num 
_pdbx_validate_peptide_omega.auth_comp_id_1 
_pdbx_validate_peptide_omega.auth_asym_id_1 
_pdbx_validate_peptide_omega.auth_seq_id_1 
_pdbx_validate_peptide_omega.PDB_ins_code_1 
_pdbx_validate_peptide_omega.label_alt_id_1 
_pdbx_validate_peptide_omega.auth_comp_id_2 
_pdbx_validate_peptide_omega.auth_asym_id_2 
_pdbx_validate_peptide_omega.auth_seq_id_2 
_pdbx_validate_peptide_omega.PDB_ins_code_2 
_pdbx_validate_peptide_omega.label_alt_id_2 
_pdbx_validate_peptide_omega.omega 
1 1 SER A 410 ? ? THR A 411 ? ? 136.43  
2 1 GLY A 412 ? ? GLU A 413 ? ? -149.09 
3 1 TRP A 557 ? ? ASP A 558 ? ? -148.80 
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 525 ? ? 0.103 'SIDE CHAIN' 
2 1 ARG A 562 ? ? 0.082 'SIDE CHAIN' 
3 1 ARG A 625 ? ? 0.094 'SIDE CHAIN' 
4 1 ARG B 141 ? ? 0.101 'SIDE CHAIN' 
5 1 ARG B 427 ? ? 0.085 'SIDE CHAIN' 
6 1 ARG H 100 ? ? 0.134 'SIDE CHAIN' 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8KDI 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8KDI 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.58 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               242503 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
loop_
_em_entity_assembly.id 
_em_entity_assembly.parent_id 
_em_entity_assembly.source 
_em_entity_assembly.type 
_em_entity_assembly.name 
_em_entity_assembly.details 
_em_entity_assembly.synonym 
_em_entity_assembly.oligomeric_details 
_em_entity_assembly.entity_id_list 
1 0 'MULTIPLE SOURCES' COMPLEX LAT1-CD98hc-Fab170 ? ? ? 1,2,4,3 
2 1 RECOMBINANT        COMPLEX LAT1-CD98hc        ? ? ? 1,2     
3 1 NATURAL            COMPLEX Fab170             ? ? ? 4,3     
# 
_em_imaging.entry_id                        8KDI 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8KDI 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8KDI 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A GLY 0   ? A GLY 1   
2   1 Y 1 A SER 1   ? A SER 2   
3   1 Y 1 A GLU 2   ? A GLU 3   
4   1 Y 1 A LEU 3   ? A LEU 4   
5   1 Y 1 A GLN 4   ? A GLN 5   
6   1 Y 1 A PRO 5   ? A PRO 6   
7   1 Y 1 A PRO 6   ? A PRO 7   
8   1 Y 1 A GLU 7   ? A GLU 8   
9   1 Y 1 A ALA 8   ? A ALA 9   
10  1 Y 1 A SER 9   ? A SER 10  
11  1 Y 1 A ILE 10  ? A ILE 11  
12  1 Y 1 A ALA 11  ? A ALA 12  
13  1 Y 1 A VAL 12  ? A VAL 13  
14  1 Y 1 A VAL 13  ? A VAL 14  
15  1 Y 1 A SER 14  ? A SER 15  
16  1 Y 1 A ILE 15  ? A ILE 16  
17  1 Y 1 A PRO 16  ? A PRO 17  
18  1 Y 1 A ARG 17  ? A ARG 18  
19  1 Y 1 A GLN 18  ? A GLN 19  
20  1 Y 1 A LEU 19  ? A LEU 20  
21  1 Y 1 A PRO 20  ? A PRO 21  
22  1 Y 1 A GLY 21  ? A GLY 22  
23  1 Y 1 A SER 22  ? A SER 23  
24  1 Y 1 A HIS 23  ? A HIS 24  
25  1 Y 1 A SER 24  ? A SER 25  
26  1 Y 1 A GLU 25  ? A GLU 26  
27  1 Y 1 A ALA 26  ? A ALA 27  
28  1 Y 1 A GLY 27  ? A GLY 28  
29  1 Y 1 A VAL 28  ? A VAL 29  
30  1 Y 1 A GLN 29  ? A GLN 30  
31  1 Y 1 A GLY 30  ? A GLY 31  
32  1 Y 1 A LEU 31  ? A LEU 32  
33  1 Y 1 A SER 32  ? A SER 33  
34  1 Y 1 A ALA 33  ? A ALA 34  
35  1 Y 1 A GLY 34  ? A GLY 35  
36  1 Y 1 A ASP 35  ? A ASP 36  
37  1 Y 1 A ASP 36  ? A ASP 37  
38  1 Y 1 A SER 37  ? A SER 38  
39  1 Y 1 A GLU 38  ? A GLU 39  
40  1 Y 1 A LEU 39  ? A LEU 40  
41  1 Y 1 A GLY 40  ? A GLY 41  
42  1 Y 1 A SER 41  ? A SER 42  
43  1 Y 1 A HIS 42  ? A HIS 43  
44  1 Y 1 A CYS 43  ? A CYS 44  
45  1 Y 1 A VAL 44  ? A VAL 45  
46  1 Y 1 A ALA 45  ? A ALA 46  
47  1 Y 1 A GLN 46  ? A GLN 47  
48  1 Y 1 A THR 47  ? A THR 48  
49  1 Y 1 A GLY 48  ? A GLY 49  
50  1 Y 1 A LEU 49  ? A LEU 50  
51  1 Y 1 A GLU 50  ? A GLU 51  
52  1 Y 1 A LEU 51  ? A LEU 52  
53  1 Y 1 A LEU 52  ? A LEU 53  
54  1 Y 1 A ALA 53  ? A ALA 54  
55  1 Y 1 A SER 54  ? A SER 55  
56  1 Y 1 A GLY 55  ? A GLY 56  
57  1 Y 1 A ASP 56  ? A ASP 57  
58  1 Y 1 A PRO 57  ? A PRO 58  
59  1 Y 1 A LEU 58  ? A LEU 59  
60  1 Y 1 A PRO 59  ? A PRO 60  
61  1 Y 1 A SER 60  ? A SER 61  
62  1 Y 1 A ALA 61  ? A ALA 62  
63  1 Y 1 A SER 62  ? A SER 63  
64  1 Y 1 A GLN 63  ? A GLN 64  
65  1 Y 1 A ASN 64  ? A ASN 65  
66  1 Y 1 A ALA 65  ? A ALA 66  
67  1 Y 1 A GLU 66  ? A GLU 67  
68  1 Y 1 A MET 67  ? A MET 68  
69  1 Y 1 A ILE 68  ? A ILE 69  
70  1 Y 1 A GLU 69  ? A GLU 70  
71  1 Y 1 A THR 70  ? A THR 71  
72  1 Y 1 A GLY 71  ? A GLY 72  
73  1 Y 1 A SER 72  ? A SER 73  
74  1 Y 1 A ASP 73  ? A ASP 74  
75  1 Y 1 A CYS 74  ? A CYS 75  
76  1 Y 1 A VAL 75  ? A VAL 76  
77  1 Y 1 A THR 76  ? A THR 77  
78  1 Y 1 A GLN 77  ? A GLN 78  
79  1 Y 1 A ALA 78  ? A ALA 79  
80  1 Y 1 A GLY 79  ? A GLY 80  
81  1 Y 1 A LEU 80  ? A LEU 81  
82  1 Y 1 A GLN 81  ? A GLN 82  
83  1 Y 1 A LEU 82  ? A LEU 83  
84  1 Y 1 A LEU 83  ? A LEU 84  
85  1 Y 1 A ALA 84  ? A ALA 85  
86  1 Y 1 A SER 85  ? A SER 86  
87  1 Y 1 A SER 86  ? A SER 87  
88  1 Y 1 A ASP 87  ? A ASP 88  
89  1 Y 1 A PRO 88  ? A PRO 89  
90  1 Y 1 A PRO 89  ? A PRO 90  
91  1 Y 1 A ALA 90  ? A ALA 91  
92  1 Y 1 A LEU 91  ? A LEU 92  
93  1 Y 1 A ALA 92  ? A ALA 93  
94  1 Y 1 A SER 93  ? A SER 94  
95  1 Y 1 A LYS 94  ? A LYS 95  
96  1 Y 1 A ASN 95  ? A ASN 96  
97  1 Y 1 A ALA 96  ? A ALA 97  
98  1 Y 1 A GLU 97  ? A GLU 98  
99  1 Y 1 A VAL 98  ? A VAL 99  
100 1 Y 1 A THR 99  ? A THR 100 
101 1 Y 1 A GLY 100 ? A GLY 101 
102 1 Y 1 A THR 101 ? A THR 102 
103 1 Y 1 A MET 102 ? A MET 103 
104 1 Y 1 A SER 103 ? A SER 104 
105 1 Y 1 A GLN 104 ? A GLN 105 
106 1 Y 1 A ASP 105 ? A ASP 106 
107 1 Y 1 A THR 106 ? A THR 107 
108 1 Y 1 A GLU 107 ? A GLU 108 
109 1 Y 1 A VAL 108 ? A VAL 109 
110 1 Y 1 A ASP 109 ? A ASP 110 
111 1 Y 1 A MET 110 ? A MET 111 
112 1 Y 1 A LYS 111 ? A LYS 112 
113 1 Y 1 A GLU 112 ? A GLU 113 
114 1 Y 1 A VAL 113 ? A VAL 114 
115 1 Y 1 A GLU 114 ? A GLU 115 
116 1 Y 1 A LEU 115 ? A LEU 116 
117 1 Y 1 A ASN 116 ? A ASN 117 
118 1 Y 1 A GLU 117 ? A GLU 118 
119 1 Y 1 A LEU 118 ? A LEU 119 
120 1 Y 1 A GLU 119 ? A GLU 120 
121 1 Y 1 A PRO 120 ? A PRO 121 
122 1 Y 1 A GLU 121 ? A GLU 122 
123 1 Y 1 A LYS 122 ? A LYS 123 
124 1 Y 1 A GLN 123 ? A GLN 124 
125 1 Y 1 A PRO 124 ? A PRO 125 
126 1 Y 1 A MET 125 ? A MET 126 
127 1 Y 1 A ASN 126 ? A ASN 127 
128 1 Y 1 A ALA 127 ? A ALA 128 
129 1 Y 1 A ALA 128 ? A ALA 129 
130 1 Y 1 A SER 129 ? A SER 130 
131 1 Y 1 A GLY 130 ? A GLY 131 
132 1 Y 1 A ALA 131 ? A ALA 132 
133 1 Y 1 A ALA 132 ? A ALA 133 
134 1 Y 1 A MET 133 ? A MET 134 
135 1 Y 1 A SER 134 ? A SER 135 
136 1 Y 1 A LEU 135 ? A LEU 136 
137 1 Y 1 A ALA 136 ? A ALA 137 
138 1 Y 1 A GLY 137 ? A GLY 138 
139 1 Y 1 A ALA 138 ? A ALA 139 
140 1 Y 1 A GLU 139 ? A GLU 140 
141 1 Y 1 A LYS 140 ? A LYS 141 
142 1 Y 1 A ASN 141 ? A ASN 142 
143 1 Y 1 A GLY 142 ? A GLY 143 
144 1 Y 1 A LEU 143 ? A LEU 144 
145 1 Y 1 A VAL 144 ? A VAL 145 
146 1 Y 1 A LYS 145 ? A LYS 146 
147 1 Y 1 A ILE 146 ? A ILE 147 
148 1 Y 1 A LYS 147 ? A LYS 148 
149 1 Y 1 A VAL 148 ? A VAL 149 
150 1 Y 1 A ALA 149 ? A ALA 150 
151 1 Y 1 A GLU 150 ? A GLU 151 
152 1 Y 1 A ASP 151 ? A ASP 152 
153 1 Y 1 A GLU 152 ? A GLU 153 
154 1 Y 1 A ALA 153 ? A ALA 154 
155 1 Y 1 A GLU 154 ? A GLU 155 
156 1 Y 1 A ALA 155 ? A ALA 156 
157 1 Y 1 A ALA 156 ? A ALA 157 
158 1 Y 1 A ALA 157 ? A ALA 158 
159 1 Y 1 A ALA 158 ? A ALA 159 
160 1 Y 1 A ALA 159 ? A ALA 160 
161 1 Y 1 A LYS 160 ? A LYS 161 
162 1 Y 1 A PHE 161 ? A PHE 162 
163 1 Y 1 B MET 1   ? B MET 1   
164 1 Y 1 B ALA 2   ? B ALA 2   
165 1 Y 1 B GLY 3   ? B GLY 3   
166 1 Y 1 B ALA 4   ? B ALA 4   
167 1 Y 1 B GLY 5   ? B GLY 5   
168 1 Y 1 B PRO 6   ? B PRO 6   
169 1 Y 1 B LYS 7   ? B LYS 7   
170 1 Y 1 B ARG 8   ? B ARG 8   
171 1 Y 1 B ARG 9   ? B ARG 9   
172 1 Y 1 B ALA 10  ? B ALA 10  
173 1 Y 1 B LEU 11  ? B LEU 11  
174 1 Y 1 B ALA 12  ? B ALA 12  
175 1 Y 1 B ALA 13  ? B ALA 13  
176 1 Y 1 B PRO 14  ? B PRO 14  
177 1 Y 1 B ALA 15  ? B ALA 15  
178 1 Y 1 B ALA 16  ? B ALA 16  
179 1 Y 1 B GLU 17  ? B GLU 17  
180 1 Y 1 B GLU 18  ? B GLU 18  
181 1 Y 1 B LYS 19  ? B LYS 19  
182 1 Y 1 B GLU 20  ? B GLU 20  
183 1 Y 1 B GLU 21  ? B GLU 21  
184 1 Y 1 B ALA 22  ? B ALA 22  
185 1 Y 1 B ARG 23  ? B ARG 23  
186 1 Y 1 B GLU 24  ? B GLU 24  
187 1 Y 1 B LYS 25  ? B LYS 25  
188 1 Y 1 B MET 26  ? B MET 26  
189 1 Y 1 B LEU 27  ? B LEU 27  
190 1 Y 1 B ALA 28  ? B ALA 28  
191 1 Y 1 B ALA 29  ? B ALA 29  
192 1 Y 1 B LYS 30  ? B LYS 30  
193 1 Y 1 B SER 31  ? B SER 31  
194 1 Y 1 B ALA 32  ? B ALA 32  
195 1 Y 1 B ASP 33  ? B ASP 33  
196 1 Y 1 B GLY 34  ? B GLY 34  
197 1 Y 1 B SER 35  ? B SER 35  
198 1 Y 1 B ALA 36  ? B ALA 36  
199 1 Y 1 B PRO 37  ? B PRO 37  
200 1 Y 1 B ALA 38  ? B ALA 38  
201 1 Y 1 B GLY 39  ? B GLY 39  
202 1 Y 1 B GLU 40  ? B GLU 40  
203 1 Y 1 B GLY 41  ? B GLY 41  
204 1 Y 1 B GLU 42  ? B GLU 42  
205 1 Y 1 B GLY 43  ? B GLY 43  
206 1 Y 1 B VAL 44  ? B VAL 44  
207 1 Y 1 B THR 45  ? B THR 45  
208 1 Y 1 B LEU 46  ? B LEU 46  
209 1 Y 1 B GLN 47  ? B GLN 47  
210 1 Y 1 B ARG 48  ? B ARG 48  
211 1 Y 1 B ASN 49  ? B ASN 49  
212 1 Y 1 B ILE 50  ? B ILE 50  
213 1 Y 1 B ASP 223 ? B ASP 223 
214 1 Y 1 B VAL 224 ? B VAL 224 
215 1 Y 1 B SER 225 ? B SER 225 
216 1 Y 1 B ASN 226 ? B ASN 226 
217 1 Y 1 B LEU 227 ? B LEU 227 
218 1 Y 1 B ASP 228 ? B ASP 228 
219 1 Y 1 B PRO 229 ? B PRO 229 
220 1 Y 1 B ASN 230 ? B ASN 230 
221 1 Y 1 B PHE 231 ? B PHE 231 
222 1 Y 1 B SER 232 ? B SER 232 
223 1 Y 1 B ASP 508 ? B ASP 508 
224 1 Y 1 B TYR 509 ? B TYR 509 
225 1 Y 1 B LYS 510 ? B LYS 510 
226 1 Y 1 B ASP 511 ? B ASP 511 
227 1 Y 1 B ASP 512 ? B ASP 512 
228 1 Y 1 B ASP 513 ? B ASP 513 
229 1 Y 1 B ASP 514 ? B ASP 514 
230 1 Y 1 B LYS 515 ? B LYS 515 
231 1 Y 1 L ASN 218 ? C ASN 218 
232 1 Y 1 L GLU 219 ? C GLU 219 
233 1 Y 1 L CYS 220 ? C CYS 220 
234 1 Y 1 H ASP 221 ? D ASP 221 
235 1 Y 1 H CYS 222 ? D CYS 222 
236 1 Y 1 H GLY 223 ? D GLY 223 
237 1 Y 1 H CYS 224 ? D CYS 224 
238 1 Y 1 H LYS 225 ? D LYS 225 
239 1 Y 1 H PRO 226 ? D PRO 226 
240 1 Y 1 H CYS 227 ? D CYS 227 
241 1 Y 1 H ILE 228 ? D ILE 228 
242 1 Y 1 H CYS 229 ? D CYS 229 
243 1 Y 1 H THR 230 ? D THR 230 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
NAG C1   C N R 247 
NAG C2   C N R 248 
NAG C3   C N R 249 
NAG C4   C N S 250 
NAG C5   C N R 251 
NAG C6   C N N 252 
NAG C7   C N N 253 
NAG C8   C N N 254 
NAG N2   N N N 255 
NAG O1   O N N 256 
NAG O3   O N N 257 
NAG O4   O N N 258 
NAG O5   O N N 259 
NAG O6   O N N 260 
NAG O7   O N N 261 
NAG H1   H N N 262 
NAG H2   H N N 263 
NAG H3   H N N 264 
NAG H4   H N N 265 
NAG H5   H N N 266 
NAG H61  H N N 267 
NAG H62  H N N 268 
NAG H81  H N N 269 
NAG H82  H N N 270 
NAG H83  H N N 271 
NAG HN2  H N N 272 
NAG HO1  H N N 273 
NAG HO3  H N N 274 
NAG HO4  H N N 275 
NAG HO6  H N N 276 
PHE N    N N N 277 
PHE CA   C N S 278 
PHE C    C N N 279 
PHE O    O N N 280 
PHE CB   C N N 281 
PHE CG   C Y N 282 
PHE CD1  C Y N 283 
PHE CD2  C Y N 284 
PHE CE1  C Y N 285 
PHE CE2  C Y N 286 
PHE CZ   C Y N 287 
PHE OXT  O N N 288 
PHE H    H N N 289 
PHE H2   H N N 290 
PHE HA   H N N 291 
PHE HB2  H N N 292 
PHE HB3  H N N 293 
PHE HD1  H N N 294 
PHE HD2  H N N 295 
PHE HE1  H N N 296 
PHE HE2  H N N 297 
PHE HZ   H N N 298 
PHE HXT  H N N 299 
PRO N    N N N 300 
PRO CA   C N S 301 
PRO C    C N N 302 
PRO O    O N N 303 
PRO CB   C N N 304 
PRO CG   C N N 305 
PRO CD   C N N 306 
PRO OXT  O N N 307 
PRO H    H N N 308 
PRO HA   H N N 309 
PRO HB2  H N N 310 
PRO HB3  H N N 311 
PRO HG2  H N N 312 
PRO HG3  H N N 313 
PRO HD2  H N N 314 
PRO HD3  H N N 315 
PRO HXT  H N N 316 
SER N    N N N 317 
SER CA   C N S 318 
SER C    C N N 319 
SER O    O N N 320 
SER CB   C N N 321 
SER OG   O N N 322 
SER OXT  O N N 323 
SER H    H N N 324 
SER H2   H N N 325 
SER HA   H N N 326 
SER HB2  H N N 327 
SER HB3  H N N 328 
SER HG   H N N 329 
SER HXT  H N N 330 
THR N    N N N 331 
THR CA   C N S 332 
THR C    C N N 333 
THR O    O N N 334 
THR CB   C N R 335 
THR OG1  O N N 336 
THR CG2  C N N 337 
THR OXT  O N N 338 
THR H    H N N 339 
THR H2   H N N 340 
THR HA   H N N 341 
THR HB   H N N 342 
THR HG1  H N N 343 
THR HG21 H N N 344 
THR HG22 H N N 345 
THR HG23 H N N 346 
THR HXT  H N N 347 
TRP N    N N N 348 
TRP CA   C N S 349 
TRP C    C N N 350 
TRP O    O N N 351 
TRP CB   C N N 352 
TRP CG   C Y N 353 
TRP CD1  C Y N 354 
TRP CD2  C Y N 355 
TRP NE1  N Y N 356 
TRP CE2  C Y N 357 
TRP CE3  C Y N 358 
TRP CZ2  C Y N 359 
TRP CZ3  C Y N 360 
TRP CH2  C Y N 361 
TRP OXT  O N N 362 
TRP H    H N N 363 
TRP H2   H N N 364 
TRP HA   H N N 365 
TRP HB2  H N N 366 
TRP HB3  H N N 367 
TRP HD1  H N N 368 
TRP HE1  H N N 369 
TRP HE3  H N N 370 
TRP HZ2  H N N 371 
TRP HZ3  H N N 372 
TRP HH2  H N N 373 
TRP HXT  H N N 374 
TYR N    N N N 375 
TYR CA   C N S 376 
TYR C    C N N 377 
TYR O    O N N 378 
TYR CB   C N N 379 
TYR CG   C Y N 380 
TYR CD1  C Y N 381 
TYR CD2  C Y N 382 
TYR CE1  C Y N 383 
TYR CE2  C Y N 384 
TYR CZ   C Y N 385 
TYR OH   O N N 386 
TYR OXT  O N N 387 
TYR H    H N N 388 
TYR H2   H N N 389 
TYR HA   H N N 390 
TYR HB2  H N N 391 
TYR HB3  H N N 392 
TYR HD1  H N N 393 
TYR HD2  H N N 394 
TYR HE1  H N N 395 
TYR HE2  H N N 396 
TYR HH   H N N 397 
TYR HXT  H N N 398 
VAL N    N N N 399 
VAL CA   C N S 400 
VAL C    C N N 401 
VAL O    O N N 402 
VAL CB   C N N 403 
VAL CG1  C N N 404 
VAL CG2  C N N 405 
VAL OXT  O N N 406 
VAL H    H N N 407 
VAL H2   H N N 408 
VAL HA   H N N 409 
VAL HB   H N N 410 
VAL HG11 H N N 411 
VAL HG12 H N N 412 
VAL HG13 H N N 413 
VAL HG21 H N N 414 
VAL HG22 H N N 415 
VAL HG23 H N N 416 
VAL HXT  H N N 417 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
NAG C1  C2   sing N N 235 
NAG C1  O1   sing N N 236 
NAG C1  O5   sing N N 237 
NAG C1  H1   sing N N 238 
NAG C2  C3   sing N N 239 
NAG C2  N2   sing N N 240 
NAG C2  H2   sing N N 241 
NAG C3  C4   sing N N 242 
NAG C3  O3   sing N N 243 
NAG C3  H3   sing N N 244 
NAG C4  C5   sing N N 245 
NAG C4  O4   sing N N 246 
NAG C4  H4   sing N N 247 
NAG C5  C6   sing N N 248 
NAG C5  O5   sing N N 249 
NAG C5  H5   sing N N 250 
NAG C6  O6   sing N N 251 
NAG C6  H61  sing N N 252 
NAG C6  H62  sing N N 253 
NAG C7  C8   sing N N 254 
NAG C7  N2   sing N N 255 
NAG C7  O7   doub N N 256 
NAG C8  H81  sing N N 257 
NAG C8  H82  sing N N 258 
NAG C8  H83  sing N N 259 
NAG N2  HN2  sing N N 260 
NAG O1  HO1  sing N N 261 
NAG O3  HO3  sing N N 262 
NAG O4  HO4  sing N N 263 
NAG O6  HO6  sing N N 264 
PHE N   CA   sing N N 265 
PHE N   H    sing N N 266 
PHE N   H2   sing N N 267 
PHE CA  C    sing N N 268 
PHE CA  CB   sing N N 269 
PHE CA  HA   sing N N 270 
PHE C   O    doub N N 271 
PHE C   OXT  sing N N 272 
PHE CB  CG   sing N N 273 
PHE CB  HB2  sing N N 274 
PHE CB  HB3  sing N N 275 
PHE CG  CD1  doub Y N 276 
PHE CG  CD2  sing Y N 277 
PHE CD1 CE1  sing Y N 278 
PHE CD1 HD1  sing N N 279 
PHE CD2 CE2  doub Y N 280 
PHE CD2 HD2  sing N N 281 
PHE CE1 CZ   doub Y N 282 
PHE CE1 HE1  sing N N 283 
PHE CE2 CZ   sing Y N 284 
PHE CE2 HE2  sing N N 285 
PHE CZ  HZ   sing N N 286 
PHE OXT HXT  sing N N 287 
PRO N   CA   sing N N 288 
PRO N   CD   sing N N 289 
PRO N   H    sing N N 290 
PRO CA  C    sing N N 291 
PRO CA  CB   sing N N 292 
PRO CA  HA   sing N N 293 
PRO C   O    doub N N 294 
PRO C   OXT  sing N N 295 
PRO CB  CG   sing N N 296 
PRO CB  HB2  sing N N 297 
PRO CB  HB3  sing N N 298 
PRO CG  CD   sing N N 299 
PRO CG  HG2  sing N N 300 
PRO CG  HG3  sing N N 301 
PRO CD  HD2  sing N N 302 
PRO CD  HD3  sing N N 303 
PRO OXT HXT  sing N N 304 
SER N   CA   sing N N 305 
SER N   H    sing N N 306 
SER N   H2   sing N N 307 
SER CA  C    sing N N 308 
SER CA  CB   sing N N 309 
SER CA  HA   sing N N 310 
SER C   O    doub N N 311 
SER C   OXT  sing N N 312 
SER CB  OG   sing N N 313 
SER CB  HB2  sing N N 314 
SER CB  HB3  sing N N 315 
SER OG  HG   sing N N 316 
SER OXT HXT  sing N N 317 
THR N   CA   sing N N 318 
THR N   H    sing N N 319 
THR N   H2   sing N N 320 
THR CA  C    sing N N 321 
THR CA  CB   sing N N 322 
THR CA  HA   sing N N 323 
THR C   O    doub N N 324 
THR C   OXT  sing N N 325 
THR CB  OG1  sing N N 326 
THR CB  CG2  sing N N 327 
THR CB  HB   sing N N 328 
THR OG1 HG1  sing N N 329 
THR CG2 HG21 sing N N 330 
THR CG2 HG22 sing N N 331 
THR CG2 HG23 sing N N 332 
THR OXT HXT  sing N N 333 
TRP N   CA   sing N N 334 
TRP N   H    sing N N 335 
TRP N   H2   sing N N 336 
TRP CA  C    sing N N 337 
TRP CA  CB   sing N N 338 
TRP CA  HA   sing N N 339 
TRP C   O    doub N N 340 
TRP C   OXT  sing N N 341 
TRP CB  CG   sing N N 342 
TRP CB  HB2  sing N N 343 
TRP CB  HB3  sing N N 344 
TRP CG  CD1  doub Y N 345 
TRP CG  CD2  sing Y N 346 
TRP CD1 NE1  sing Y N 347 
TRP CD1 HD1  sing N N 348 
TRP CD2 CE2  doub Y N 349 
TRP CD2 CE3  sing Y N 350 
TRP NE1 CE2  sing Y N 351 
TRP NE1 HE1  sing N N 352 
TRP CE2 CZ2  sing Y N 353 
TRP CE3 CZ3  doub Y N 354 
TRP CE3 HE3  sing N N 355 
TRP CZ2 CH2  doub Y N 356 
TRP CZ2 HZ2  sing N N 357 
TRP CZ3 CH2  sing Y N 358 
TRP CZ3 HZ3  sing N N 359 
TRP CH2 HH2  sing N N 360 
TRP OXT HXT  sing N N 361 
TYR N   CA   sing N N 362 
TYR N   H    sing N N 363 
TYR N   H2   sing N N 364 
TYR CA  C    sing N N 365 
TYR CA  CB   sing N N 366 
TYR CA  HA   sing N N 367 
TYR C   O    doub N N 368 
TYR C   OXT  sing N N 369 
TYR CB  CG   sing N N 370 
TYR CB  HB2  sing N N 371 
TYR CB  HB3  sing N N 372 
TYR CG  CD1  doub Y N 373 
TYR CG  CD2  sing Y N 374 
TYR CD1 CE1  sing Y N 375 
TYR CD1 HD1  sing N N 376 
TYR CD2 CE2  doub Y N 377 
TYR CD2 HD2  sing N N 378 
TYR CE1 CZ   doub Y N 379 
TYR CE1 HE1  sing N N 380 
TYR CE2 CZ   sing Y N 381 
TYR CE2 HE2  sing N N 382 
TYR CZ  OH   sing N N 383 
TYR OH  HH   sing N N 384 
TYR OXT HXT  sing N N 385 
VAL N   CA   sing N N 386 
VAL N   H    sing N N 387 
VAL N   H2   sing N N 388 
VAL CA  C    sing N N 389 
VAL CA  CB   sing N N 390 
VAL CA  HA   sing N N 391 
VAL C   O    doub N N 392 
VAL C   OXT  sing N N 393 
VAL CB  CG1  sing N N 394 
VAL CB  CG2  sing N N 395 
VAL CB  HB   sing N N 396 
VAL CG1 HG11 sing N N 397 
VAL CG1 HG12 sing N N 398 
VAL CG1 HG13 sing N N 399 
VAL CG2 HG21 sing N N 400 
VAL CG2 HG22 sing N N 401 
VAL CG2 HG23 sing N N 402 
VAL OXT HXT  sing N N 403 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-08-09 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8KDI 
_em_admin.last_update        2025-02-26 
_em_admin.map_release_date   2025-02-12 
_em_admin.title              'Structure of apo inward-open LAT1-CD98hc-Fab170 in nanodisc, consensus map' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
loop_
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
_em_entity_assembly_naturalsource.details 
? ? 2 2 9606  'Homo sapiens' ? ? ? ? ? 
? ? 3 3 10090 'Mus musculus' ? ? ? ? ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   2 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         51 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Max Planck Society' 
_pdbx_audit_support.country                Germany 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8KDI 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . THR A 1 163 ? 105.402 114.069 55.052  1.00 286.41 ? 162 THR A N   1 
ATOM   2     C CA  . THR A 1 163 ? 105.659 115.302 55.854  1.00 340.84 ? 162 THR A CA  1 
ATOM   3     C C   . THR A 1 163 ? 107.033 115.192 56.522  1.00 360.50 ? 162 THR A C   1 
ATOM   4     O O   . THR A 1 163 ? 107.495 114.079 56.778  1.00 370.48 ? 162 THR A O   1 
ATOM   5     C CB  . THR A 1 163 ? 104.508 115.540 56.841  1.00 335.97 ? 162 THR A CB  1 
ATOM   6     O OG1 . THR A 1 163 ? 103.339 115.652 56.019  1.00 238.99 ? 162 THR A OG1 1 
ATOM   7     C CG2 . THR A 1 163 ? 104.669 116.756 57.738  1.00 301.82 ? 162 THR A CG2 1 
ATOM   8     N N   . GLY A 1 164 ? 107.664 116.356 56.790  1.00 314.18 ? 163 GLY A N   1 
ATOM   9     C CA  . GLY A 1 164 ? 109.056 116.459 57.220  1.00 282.44 ? 163 GLY A CA  1 
ATOM   10    C C   . GLY A 1 164 ? 110.051 116.122 56.099  1.00 313.41 ? 163 GLY A C   1 
ATOM   11    O O   . GLY A 1 164 ? 109.670 115.911 54.948  1.00 315.38 ? 163 GLY A O   1 
ATOM   12    N N   . LEU A 1 165 ? 111.343 116.063 56.442  1.00 291.44 ? 164 LEU A N   1 
ATOM   13    C CA  . LEU A 1 165 ? 112.400 115.729 55.492  1.00 258.73 ? 164 LEU A CA  1 
ATOM   14    C C   . LEU A 1 165 ? 112.353 114.226 55.174  1.00 257.67 ? 164 LEU A C   1 
ATOM   15    O O   . LEU A 1 165 ? 112.318 113.412 56.090  1.00 346.39 ? 164 LEU A O   1 
ATOM   16    C CB  . LEU A 1 165 ? 113.725 116.161 56.131  1.00 265.62 ? 164 LEU A CB  1 
ATOM   17    C CG  . LEU A 1 165 ? 114.955 116.190 55.232  1.00 307.56 ? 164 LEU A CG  1 
ATOM   18    C CD1 . LEU A 1 165 ? 114.801 117.241 54.149  1.00 368.05 ? 164 LEU A CD1 1 
ATOM   19    C CD2 . LEU A 1 165 ? 116.200 116.471 56.054  1.00 312.72 ? 164 LEU A CD2 1 
ATOM   20    N N   . SER A 1 166 ? 112.339 113.831 53.887  1.00 267.88 ? 165 SER A N   1 
ATOM   21    C CA  . SER A 1 166 ? 112.073 112.445 53.498  1.00 278.81 ? 165 SER A CA  1 
ATOM   22    C C   . SER A 1 166 ? 113.364 111.622 53.373  1.00 260.09 ? 165 SER A C   1 
ATOM   23    O O   . SER A 1 166 ? 114.473 112.174 53.386  1.00 197.67 ? 165 SER A O   1 
ATOM   24    C CB  . SER A 1 166 ? 111.266 112.400 52.218  1.00 298.15 ? 165 SER A CB  1 
ATOM   25    O OG  . SER A 1 166 ? 110.745 111.097 51.976  1.00 265.05 ? 165 SER A OG  1 
ATOM   26    N N   . LYS A 1 167 ? 113.192 110.285 53.230  1.00 248.04 ? 166 LYS A N   1 
ATOM   27    C CA  . LYS A 1 167 ? 114.269 109.306 53.058  1.00 279.62 ? 166 LYS A CA  1 
ATOM   28    C C   . LYS A 1 167 ? 115.250 109.741 51.962  1.00 336.23 ? 166 LYS A C   1 
ATOM   29    O O   . LYS A 1 167 ? 116.477 109.661 52.146  1.00 314.97 ? 166 LYS A O   1 
ATOM   30    C CB  . LYS A 1 167 ? 113.693 107.916 52.736  1.00 249.92 ? 166 LYS A CB  1 
ATOM   31    C CG  . LYS A 1 167 ? 114.730 106.796 52.736  1.00 288.60 ? 166 LYS A CG  1 
ATOM   32    C CD  . LYS A 1 167 ? 114.247 105.457 52.232  1.00 325.77 ? 166 LYS A CD  1 
ATOM   33    C CE  . LYS A 1 167 ? 115.190 104.320 52.584  1.00 338.01 ? 166 LYS A CE  1 
ATOM   34    N NZ  . LYS A 1 167 ? 116.498 104.387 51.880  1.00 314.86 ? 166 LYS A NZ  1 
ATOM   35    N N   . GLU A 1 168 ? 114.678 110.214 50.840  1.00 386.01 ? 167 GLU A N   1 
ATOM   36    C CA  . GLU A 1 168 ? 115.408 110.565 49.632  1.00 391.78 ? 167 GLU A CA  1 
ATOM   37    C C   . GLU A 1 168 ? 116.292 111.801 49.842  1.00 386.20 ? 167 GLU A C   1 
ATOM   38    O O   . GLU A 1 168 ? 117.249 111.980 49.086  1.00 416.53 ? 167 GLU A O   1 
ATOM   39    C CB  . GLU A 1 168 ? 114.434 110.797 48.469  1.00 429.33 ? 167 GLU A CB  1 
ATOM   40    C CG  . GLU A 1 168 ? 113.545 109.600 48.128  1.00 490.59 ? 167 GLU A CG  1 
ATOM   41    C CD  . GLU A 1 168 ? 112.269 109.404 48.941  1.00 527.64 ? 167 GLU A CD  1 
ATOM   42    O OE1 . GLU A 1 168 ? 112.055 110.155 49.920  1.00 539.53 ? 167 GLU A OE1 1 
ATOM   43    O OE2 . GLU A 1 168 ? 111.487 108.496 48.593  1.00 537.97 ? 167 GLU A OE2 1 
ATOM   44    N N   . GLU A 1 169 ? 115.982 112.652 50.841  1.00 381.11 ? 168 GLU A N   1 
ATOM   45    C CA  . GLU A 1 169 ? 116.871 113.732 51.263  1.00 374.91 ? 168 GLU A CA  1 
ATOM   46    C C   . GLU A 1 169 ? 117.886 113.231 52.296  1.00 345.83 ? 168 GLU A C   1 
ATOM   47    O O   . GLU A 1 169 ? 119.090 113.402 52.110  1.00 404.78 ? 168 GLU A O   1 
ATOM   48    C CB  . GLU A 1 169 ? 116.067 114.910 51.817  1.00 376.92 ? 168 GLU A CB  1 
ATOM   49    C CG  . GLU A 1 169 ? 115.242 115.643 50.767  1.00 386.08 ? 168 GLU A CG  1 
ATOM   50    C CD  . GLU A 1 169 ? 113.850 115.088 50.509  1.00 386.86 ? 168 GLU A CD  1 
ATOM   51    O OE1 . GLU A 1 169 ? 113.017 115.136 51.434  1.00 426.55 ? 168 GLU A OE1 1 
ATOM   52    O OE2 . GLU A 1 169 ? 113.601 114.618 49.382  1.00 356.63 ? 168 GLU A OE2 1 
ATOM   53    N N   . LEU A 1 170 ? 117.410 112.610 53.383  1.00 299.88 ? 169 LEU A N   1 
ATOM   54    C CA  . LEU A 1 170 ? 118.262 112.287 54.527  1.00 333.15 ? 169 LEU A CA  1 
ATOM   55    C C   . LEU A 1 170 ? 119.438 111.360 54.198  1.00 365.84 ? 169 LEU A C   1 
ATOM   56    O O   . LEU A 1 170 ? 120.472 111.462 54.863  1.00 350.95 ? 169 LEU A O   1 
ATOM   57    C CB  . LEU A 1 170 ? 117.389 111.700 55.635  1.00 334.87 ? 169 LEU A CB  1 
ATOM   58    C CG  . LEU A 1 170 ? 116.716 112.755 56.501  1.00 324.87 ? 169 LEU A CG  1 
ATOM   59    C CD1 . LEU A 1 170 ? 115.495 112.189 57.192  1.00 363.48 ? 169 LEU A CD1 1 
ATOM   60    C CD2 . LEU A 1 170 ? 117.694 113.297 57.533  1.00 361.61 ? 169 LEU A CD2 1 
ATOM   61    N N   . LEU A 1 171 ? 119.315 110.491 53.182  1.00 376.06 ? 170 LEU A N   1 
ATOM   62    C CA  . LEU A 1 171 ? 120.405 109.587 52.811  1.00 403.73 ? 170 LEU A CA  1 
ATOM   63    C C   . LEU A 1 171 ? 121.694 110.313 52.359  1.00 469.50 ? 170 LEU A C   1 
ATOM   64    O O   . LEU A 1 171 ? 122.730 109.646 52.279  1.00 479.23 ? 170 LEU A O   1 
ATOM   65    C CB  . LEU A 1 171 ? 119.901 108.572 51.762  1.00 440.39 ? 170 LEU A CB  1 
ATOM   66    C CG  . LEU A 1 171 ? 119.401 109.078 50.401  1.00 513.85 ? 170 LEU A CG  1 
ATOM   67    C CD1 . LEU A 1 171 ? 120.540 109.352 49.422  1.00 555.79 ? 170 LEU A CD1 1 
ATOM   68    C CD2 . LEU A 1 171 ? 118.439 108.072 49.780  1.00 512.09 ? 170 LEU A CD2 1 
ATOM   69    N N   . LYS A 1 172 ? 121.670 111.638 52.063  1.00 514.09 ? 171 LYS A N   1 
ATOM   70    C CA  . LYS A 1 172 ? 122.880 112.414 51.757  1.00 505.33 ? 171 LYS A CA  1 
ATOM   71    C C   . LYS A 1 172 ? 123.188 113.546 52.758  1.00 485.52 ? 171 LYS A C   1 
ATOM   72    O O   . LYS A 1 172 ? 124.251 114.162 52.649  1.00 478.27 ? 171 LYS A O   1 
ATOM   73    C CB  . LYS A 1 172 ? 122.775 112.989 50.337  1.00 514.81 ? 171 LYS A CB  1 
ATOM   74    C CG  . LYS A 1 172 ? 121.890 114.222 50.160  1.00 536.07 ? 171 LYS A CG  1 
ATOM   75    C CD  . LYS A 1 172 ? 121.178 114.304 48.824  1.00 558.57 ? 171 LYS A CD  1 
ATOM   76    C CE  . LYS A 1 172 ? 120.038 113.312 48.715  1.00 587.95 ? 171 LYS A CE  1 
ATOM   77    N NZ  . LYS A 1 172 ? 119.165 113.579 47.545  1.00 593.96 ? 171 LYS A NZ  1 
ATOM   78    N N   . VAL A 1 173 ? 122.289 113.823 53.721  1.00 469.59 ? 172 VAL A N   1 
ATOM   79    C CA  . VAL A 1 173 ? 122.473 114.854 54.745  1.00 429.13 ? 172 VAL A CA  1 
ATOM   80    C C   . VAL A 1 173 ? 123.351 114.340 55.903  1.00 428.33 ? 172 VAL A C   1 
ATOM   81    O O   . VAL A 1 173 ? 123.880 115.142 56.677  1.00 429.81 ? 172 VAL A O   1 
ATOM   82    C CB  . VAL A 1 173 ? 121.095 115.378 55.215  1.00 370.69 ? 172 VAL A CB  1 
ATOM   83    C CG1 . VAL A 1 173 ? 121.181 116.338 56.399  1.00 327.64 ? 172 VAL A CG1 1 
ATOM   84    C CG2 . VAL A 1 173 ? 120.340 116.043 54.069  1.00 329.12 ? 172 VAL A CG2 1 
ATOM   85    N N   . ALA A 1 174 ? 123.520 113.011 56.025  1.00 385.69 ? 173 ALA A N   1 
ATOM   86    C CA  . ALA A 1 174 ? 124.385 112.367 57.011  1.00 362.43 ? 173 ALA A CA  1 
ATOM   87    C C   . ALA A 1 174 ? 125.890 112.527 56.711  1.00 401.69 ? 173 ALA A C   1 
ATOM   88    O O   . ALA A 1 174 ? 126.587 111.535 56.483  1.00 362.30 ? 173 ALA A O   1 
ATOM   89    C CB  . ALA A 1 174 ? 123.982 110.907 57.060  1.00 332.94 ? 173 ALA A CB  1 
ATOM   90    N N   . GLY A 1 175 ? 126.413 113.767 56.729  1.00 399.12 ? 174 GLY A N   1 
ATOM   91    C CA  . GLY A 1 175 ? 127.822 114.028 56.441  1.00 347.75 ? 174 GLY A CA  1 
ATOM   92    C C   . GLY A 1 175 ? 128.723 113.576 57.590  1.00 321.45 ? 174 GLY A C   1 
ATOM   93    O O   . GLY A 1 175 ? 128.537 114.038 58.708  1.00 321.79 ? 174 GLY A O   1 
ATOM   94    N N   . SER A 1 176 ? 129.694 112.688 57.305  1.00 335.25 ? 175 SER A N   1 
ATOM   95    C CA  . SER A 1 176 ? 130.385 111.887 58.319  1.00 377.89 ? 175 SER A CA  1 
ATOM   96    C C   . SER A 1 176 ? 131.056 112.724 59.427  1.00 456.14 ? 175 SER A C   1 
ATOM   97    O O   . SER A 1 176 ? 130.909 112.371 60.602  1.00 490.21 ? 175 SER A O   1 
ATOM   98    C CB  . SER A 1 176 ? 131.369 110.922 57.663  1.00 338.61 ? 175 SER A CB  1 
ATOM   99    O OG  . SER A 1 176 ? 132.009 110.093 58.625  1.00 294.39 ? 175 SER A OG  1 
ATOM   100   N N   . PRO A 1 177 ? 131.800 113.832 59.141  1.00 495.40 ? 176 PRO A N   1 
ATOM   101   C CA  . PRO A 1 177 ? 132.414 114.658 60.196  1.00 483.17 ? 176 PRO A CA  1 
ATOM   102   C C   . PRO A 1 177 ? 131.480 115.266 61.253  1.00 450.68 ? 176 PRO A C   1 
ATOM   103   O O   . PRO A 1 177 ? 131.956 115.590 62.340  1.00 392.94 ? 176 PRO A O   1 
ATOM   104   C CB  . PRO A 1 177 ? 133.096 115.801 59.416  1.00 484.75 ? 176 PRO A CB  1 
ATOM   105   C CG  . PRO A 1 177 ? 133.333 115.227 58.043  1.00 501.67 ? 176 PRO A CG  1 
ATOM   106   C CD  . PRO A 1 177 ? 132.118 114.357 57.802  1.00 513.06 ? 176 PRO A CD  1 
ATOM   107   N N   . GLY A 1 178 ? 130.178 115.412 60.936  1.00 431.07 ? 177 GLY A N   1 
ATOM   108   C CA  . GLY A 1 178 ? 129.178 115.925 61.868  1.00 392.24 ? 177 GLY A CA  1 
ATOM   109   C C   . GLY A 1 178 ? 128.329 114.821 62.508  1.00 371.59 ? 177 GLY A C   1 
ATOM   110   O O   . GLY A 1 178 ? 128.669 114.285 63.564  1.00 386.76 ? 177 GLY A O   1 
ATOM   111   N N   . TRP A 1 179 ? 127.217 114.476 61.842  1.00 326.38 ? 178 TRP A N   1 
ATOM   112   C CA  . TRP A 1 179 ? 126.147 113.704 62.462  1.00 260.29 ? 178 TRP A CA  1 
ATOM   113   C C   . TRP A 1 179 ? 126.555 112.249 62.699  1.00 231.17 ? 178 TRP A C   1 
ATOM   114   O O   . TRP A 1 179 ? 126.187 111.729 63.746  1.00 360.65 ? 178 TRP A O   1 
ATOM   115   C CB  . TRP A 1 179 ? 124.836 113.821 61.673  1.00 253.46 ? 178 TRP A CB  1 
ATOM   116   C CG  . TRP A 1 179 ? 124.410 115.255 61.494  1.00 294.93 ? 178 TRP A CG  1 
ATOM   117   C CD1 . TRP A 1 179 ? 124.471 115.926 60.312  1.00 355.14 ? 178 TRP A CD1 1 
ATOM   118   C CD2 . TRP A 1 179 ? 123.893 116.195 62.473  1.00 288.77 ? 178 TRP A CD2 1 
ATOM   119   N NE1 . TRP A 1 179 ? 124.018 117.211 60.477  1.00 379.67 ? 178 TRP A NE1 1 
ATOM   120   C CE2 . TRP A 1 179 ? 123.661 117.409 61.788  1.00 334.42 ? 178 TRP A CE2 1 
ATOM   121   C CE3 . TRP A 1 179 ? 123.607 116.135 63.845  1.00 309.45 ? 178 TRP A CE3 1 
ATOM   122   C CZ2 . TRP A 1 179 ? 123.153 118.543 62.434  1.00 302.70 ? 178 TRP A CZ2 1 
ATOM   123   C CZ3 . TRP A 1 179 ? 123.108 117.256 64.481  1.00 305.20 ? 178 TRP A CZ3 1 
ATOM   124   C CH2 . TRP A 1 179 ? 122.882 118.444 63.783  1.00 278.67 ? 178 TRP A CH2 1 
ATOM   125   N N   . VAL A 1 180 ? 127.311 111.595 61.804  1.00 174.58 ? 179 VAL A N   1 
ATOM   126   C CA  . VAL A 1 180 ? 127.663 110.182 61.996  1.00 225.89 ? 179 VAL A CA  1 
ATOM   127   C C   . VAL A 1 180 ? 128.572 110.009 63.222  1.00 258.02 ? 179 VAL A C   1 
ATOM   128   O O   . VAL A 1 180 ? 128.333 109.097 64.022  1.00 338.82 ? 179 VAL A O   1 
ATOM   129   C CB  . VAL A 1 180 ? 128.297 109.531 60.749  1.00 299.86 ? 179 VAL A CB  1 
ATOM   130   C CG1 . VAL A 1 180 ? 128.686 108.062 60.980  1.00 258.47 ? 179 VAL A CG1 1 
ATOM   131   C CG2 . VAL A 1 180 ? 127.373 109.654 59.543  1.00 366.64 ? 179 VAL A CG2 1 
ATOM   132   N N   . ARG A 1 181 ? 129.584 110.879 63.382  1.00 269.91 ? 180 ARG A N   1 
ATOM   133   C CA  . ARG A 1 181 ? 130.441 110.859 64.568  1.00 328.22 ? 180 ARG A CA  1 
ATOM   134   C C   . ARG A 1 181 ? 129.627 111.208 65.833  1.00 374.30 ? 180 ARG A C   1 
ATOM   135   O O   . ARG A 1 181 ? 129.845 110.602 66.886  1.00 375.92 ? 180 ARG A O   1 
ATOM   136   C CB  . ARG A 1 181 ? 131.643 111.788 64.346  1.00 330.31 ? 180 ARG A CB  1 
ATOM   137   C CG  . ARG A 1 181 ? 132.824 111.572 65.285  1.00 300.14 ? 180 ARG A CG  1 
ATOM   138   C CD  . ARG A 1 181 ? 133.604 110.283 65.057  1.00 353.05 ? 180 ARG A CD  1 
ATOM   139   N NE  . ARG A 1 181 ? 134.804 110.197 65.903  1.00 375.89 ? 180 ARG A NE  1 
ATOM   140   C CZ  . ARG A 1 181 ? 135.666 109.168 65.965  1.00 346.22 ? 180 ARG A CZ  1 
ATOM   141   N NH1 . ARG A 1 181 ? 136.670 109.186 66.835  1.00 226.63 ? 180 ARG A NH1 1 
ATOM   142   N NH2 . ARG A 1 181 ? 135.530 108.115 65.170  1.00 342.74 ? 180 ARG A NH2 1 
ATOM   143   N N   . THR A 1 182 ? 128.689 112.173 65.736  1.00 369.84 ? 181 THR A N   1 
ATOM   144   C CA  . THR A 1 182 ? 127.802 112.562 66.836  1.00 314.64 ? 181 THR A CA  1 
ATOM   145   C C   . THR A 1 182 ? 126.934 111.385 67.310  1.00 245.09 ? 181 THR A C   1 
ATOM   146   O O   . THR A 1 182 ? 126.856 111.130 68.510  1.00 199.38 ? 181 THR A O   1 
ATOM   147   C CB  . THR A 1 182 ? 126.931 113.772 66.446  1.00 314.24 ? 181 THR A CB  1 
ATOM   148   O OG1 . THR A 1 182 ? 127.781 114.869 66.103  1.00 252.81 ? 181 THR A OG1 1 
ATOM   149   C CG2 . THR A 1 182 ? 125.982 114.240 67.530  1.00 309.00 ? 181 THR A CG2 1 
ATOM   150   N N   . ARG A 1 183 ? 126.285 110.676 66.374  1.00 257.27 ? 182 ARG A N   1 
ATOM   151   C CA  . ARG A 1 183 ? 125.423 109.534 66.680  1.00 234.77 ? 182 ARG A CA  1 
ATOM   152   C C   . ARG A 1 183 ? 126.213 108.333 67.214  1.00 211.75 ? 182 ARG A C   1 
ATOM   153   O O   . ARG A 1 183 ? 125.677 107.609 68.054  1.00 347.09 ? 182 ARG A O   1 
ATOM   154   C CB  . ARG A 1 183 ? 124.564 109.169 65.463  1.00 219.80 ? 182 ARG A CB  1 
ATOM   155   C CG  . ARG A 1 183 ? 123.400 110.134 65.272  1.00 227.94 ? 182 ARG A CG  1 
ATOM   156   C CD  . ARG A 1 183 ? 122.454 109.669 64.168  1.00 278.71 ? 182 ARG A CD  1 
ATOM   157   N NE  . ARG A 1 183 ? 122.726 110.285 62.874  1.00 283.25 ? 182 ARG A NE  1 
ATOM   158   C CZ  . ARG A 1 183 ? 123.330 109.700 61.839  1.00 267.04 ? 182 ARG A CZ  1 
ATOM   159   N NH1 . ARG A 1 183 ? 123.397 110.340 60.688  1.00 240.47 ? 182 ARG A NH1 1 
ATOM   160   N NH2 . ARG A 1 183 ? 123.870 108.495 61.948  1.00 259.22 ? 182 ARG A NH2 1 
ATOM   161   N N   . TRP A 1 184 ? 127.462 108.124 66.780  1.00 200.21 ? 183 TRP A N   1 
ATOM   162   C CA  . TRP A 1 184 ? 128.346 107.187 67.461  1.00 213.71 ? 183 TRP A CA  1 
ATOM   163   C C   . TRP A 1 184 ? 128.588 107.594 68.925  1.00 229.40 ? 183 TRP A C   1 
ATOM   164   O O   . TRP A 1 184 ? 128.476 106.750 69.825  1.00 283.69 ? 183 TRP A O   1 
ATOM   165   C CB  . TRP A 1 184 ? 129.675 107.067 66.718  1.00 251.79 ? 183 TRP A CB  1 
ATOM   166   C CG  . TRP A 1 184 ? 130.653 106.182 67.438  1.00 322.10 ? 183 TRP A CG  1 
ATOM   167   C CD1 . TRP A 1 184 ? 131.722 106.573 68.194  1.00 346.59 ? 183 TRP A CD1 1 
ATOM   168   C CD2 . TRP A 1 184 ? 130.643 104.735 67.455  1.00 351.01 ? 183 TRP A CD2 1 
ATOM   169   N NE1 . TRP A 1 184 ? 132.379 105.472 68.682  1.00 368.71 ? 183 TRP A NE1 1 
ATOM   170   C CE2 . TRP A 1 184 ? 131.749 104.330 68.247  1.00 376.87 ? 183 TRP A CE2 1 
ATOM   171   C CE3 . TRP A 1 184 ? 129.828 103.739 66.880  1.00 286.14 ? 183 TRP A CE3 1 
ATOM   172   C CZ2 . TRP A 1 184 ? 132.047 102.979 68.476  1.00 342.99 ? 183 TRP A CZ2 1 
ATOM   173   C CZ3 . TRP A 1 184 ? 130.125 102.406 67.106  1.00 292.69 ? 183 TRP A CZ3 1 
ATOM   174   C CH2 . TRP A 1 184 ? 131.222 102.034 67.894  1.00 318.41 ? 183 TRP A CH2 1 
ATOM   175   N N   . ALA A 1 185 ? 128.904 108.879 69.165  1.00 230.15 ? 184 ALA A N   1 
ATOM   176   C CA  . ALA A 1 185 ? 129.147 109.393 70.516  1.00 294.27 ? 184 ALA A CA  1 
ATOM   177   C C   . ALA A 1 185 ? 127.927 109.231 71.447  1.00 295.86 ? 184 ALA A C   1 
ATOM   178   O O   . ALA A 1 185 ? 128.086 108.764 72.578  1.00 312.32 ? 184 ALA A O   1 
ATOM   179   C CB  . ALA A 1 185 ? 129.627 110.831 70.452  1.00 292.21 ? 184 ALA A CB  1 
ATOM   180   N N   . LEU A 1 186 ? 126.713 109.588 71.005  1.00 242.97 ? 185 LEU A N   1 
ATOM   181   C CA  . LEU A 1 186 ? 125.524 109.415 71.841  1.00 184.38 ? 185 LEU A CA  1 
ATOM   182   C C   . LEU A 1 186 ? 125.220 107.941 72.104  1.00 179.62 ? 185 LEU A C   1 
ATOM   183   O O   . LEU A 1 186 ? 124.814 107.622 73.216  1.00 265.90 ? 185 LEU A O   1 
ATOM   184   C CB  . LEU A 1 186 ? 124.294 110.050 71.184  1.00 201.19 ? 185 LEU A CB  1 
ATOM   185   C CG  . LEU A 1 186 ? 124.233 111.570 71.134  1.00 255.17 ? 185 LEU A CG  1 
ATOM   186   C CD1 . LEU A 1 186 ? 122.831 111.979 70.727  1.00 275.61 ? 185 LEU A CD1 1 
ATOM   187   C CD2 . LEU A 1 186 ? 124.593 112.228 72.461  1.00 268.73 ? 185 LEU A CD2 1 
ATOM   188   N N   . LEU A 1 187 ? 125.396 107.053 71.115  1.00 202.09 ? 186 LEU A N   1 
ATOM   189   C CA  . LEU A 1 187 ? 125.163 105.627 71.320  1.00 178.67 ? 186 LEU A CA  1 
ATOM   190   C C   . LEU A 1 187 ? 126.162 105.072 72.356  1.00 195.36 ? 186 LEU A C   1 
ATOM   191   O O   . LEU A 1 187 ? 125.753 104.294 73.228  1.00 284.40 ? 186 LEU A O   1 
ATOM   192   C CB  . LEU A 1 187 ? 125.245 104.918 69.962  1.00 233.00 ? 186 LEU A CB  1 
ATOM   193   C CG  . LEU A 1 187 ? 124.816 103.452 69.855  1.00 256.95 ? 186 LEU A CG  1 
ATOM   194   C CD1 . LEU A 1 187 ? 125.871 102.456 70.438  1.00 196.02 ? 186 LEU A CD1 1 
ATOM   195   C CD2 . LEU A 1 187 ? 123.416 103.309 70.459  1.00 240.31 ? 186 LEU A CD2 1 
ATOM   196   N N   . LEU A 1 188 ? 127.444 105.477 72.310  1.00 160.75 ? 187 LEU A N   1 
ATOM   197   C CA  . LEU A 1 188 ? 128.374 105.111 73.368  1.00 199.03 ? 187 LEU A CA  1 
ATOM   198   C C   . LEU A 1 188 ? 127.995 105.760 74.714  1.00 207.55 ? 187 LEU A C   1 
ATOM   199   O O   . LEU A 1 188 ? 128.095 105.109 75.750  1.00 247.45 ? 187 LEU A O   1 
ATOM   200   C CB  . LEU A 1 188 ? 129.799 105.491 72.955  1.00 282.89 ? 187 LEU A CB  1 
ATOM   201   C CG  . LEU A 1 188 ? 130.879 105.173 73.995  1.00 342.38 ? 187 LEU A CG  1 
ATOM   202   C CD1 . LEU A 1 188 ? 130.972 103.670 74.261  1.00 304.71 ? 187 LEU A CD1 1 
ATOM   203   C CD2 . LEU A 1 188 ? 132.228 105.729 73.562  1.00 397.75 ? 187 LEU A CD2 1 
ATOM   204   N N   . LEU A 1 189 ? 127.562 107.029 74.727  1.00 189.00 ? 188 LEU A N   1 
ATOM   205   C CA  . LEU A 1 189 ? 127.148 107.699 75.966  1.00 237.13 ? 188 LEU A CA  1 
ATOM   206   C C   . LEU A 1 189 ? 125.969 106.988 76.653  1.00 225.29 ? 188 LEU A C   1 
ATOM   207   O O   . LEU A 1 189 ? 125.946 106.887 77.871  1.00 194.13 ? 188 LEU A O   1 
ATOM   208   C CB  . LEU A 1 189 ? 126.816 109.171 75.673  1.00 257.66 ? 188 LEU A CB  1 
ATOM   209   C CG  . LEU A 1 189 ? 126.287 110.012 76.841  1.00 327.06 ? 188 LEU A CG  1 
ATOM   210   C CD1 . LEU A 1 189 ? 127.316 110.126 77.958  1.00 382.03 ? 188 LEU A CD1 1 
ATOM   211   C CD2 . LEU A 1 189 ? 125.877 111.391 76.368  1.00 360.54 ? 188 LEU A CD2 1 
ATOM   212   N N   . PHE A 1 190 ? 124.991 106.482 75.893  1.00 225.61 ? 189 PHE A N   1 
ATOM   213   C CA  . PHE A 1 190 ? 123.906 105.684 76.459  1.00 136.57 ? 189 PHE A CA  1 
ATOM   214   C C   . PHE A 1 190 ? 124.454 104.430 77.119  1.00 128.17 ? 189 PHE A C   1 
ATOM   215   O O   . PHE A 1 190 ? 124.159 104.270 78.313  1.00 262.91 ? 189 PHE A O   1 
ATOM   216   C CB  . PHE A 1 190 ? 122.946 105.265 75.371  1.00 165.30 ? 189 PHE A CB  1 
ATOM   217   C CG  . PHE A 1 190 ? 121.913 104.217 75.684  1.00 200.87 ? 189 PHE A CG  1 
ATOM   218   C CD1 . PHE A 1 190 ? 122.189 102.831 75.655  1.00 112.02 ? 189 PHE A CD1 1 
ATOM   219   C CD2 . PHE A 1 190 ? 120.630 104.660 75.972  1.00 241.31 ? 189 PHE A CD2 1 
ATOM   220   C CE1 . PHE A 1 190 ? 121.174 101.924 75.935  1.00 183.98 ? 189 PHE A CE1 1 
ATOM   221   C CE2 . PHE A 1 190 ? 119.612 103.747 76.233  1.00 268.86 ? 189 PHE A CE2 1 
ATOM   222   C CZ  . PHE A 1 190 ? 119.892 102.384 76.218  1.00 290.60 ? 189 PHE A CZ  1 
ATOM   223   N N   . TRP A 1 191 ? 125.231 103.574 76.421  1.00 103.44 ? 190 TRP A N   1 
ATOM   224   C CA  . TRP A 1 191 ? 125.743 102.380 77.096  1.00 192.37 ? 190 TRP A CA  1 
ATOM   225   C C   . TRP A 1 191 ? 126.707 102.663 78.263  1.00 226.07 ? 190 TRP A C   1 
ATOM   226   O O   . TRP A 1 191 ? 126.669 101.917 79.248  1.00 212.39 ? 190 TRP A O   1 
ATOM   227   C CB  . TRP A 1 191 ? 126.335 101.409 76.079  1.00 201.15 ? 190 TRP A CB  1 
ATOM   228   C CG  . TRP A 1 191 ? 125.241 100.671 75.384  1.00 170.18 ? 190 TRP A CG  1 
ATOM   229   C CD1 . TRP A 1 191 ? 124.755 100.976 74.162  1.00 204.48 ? 190 TRP A CD1 1 
ATOM   230   C CD2 . TRP A 1 191 ? 124.518 99.515  75.852  1.00 191.55 ? 190 TRP A CD2 1 
ATOM   231   N NE1 . TRP A 1 191 ? 123.764 100.093 73.830  1.00 255.72 ? 190 TRP A NE1 1 
ATOM   232   C CE2 . TRP A 1 191 ? 123.596 99.184  74.842  1.00 240.57 ? 190 TRP A CE2 1 
ATOM   233   C CE3 . TRP A 1 191 ? 124.554 98.725  77.010  1.00 263.00 ? 190 TRP A CE3 1 
ATOM   234   C CZ2 . TRP A 1 191 ? 122.720 98.102  74.954  1.00 300.58 ? 190 TRP A CZ2 1 
ATOM   235   C CZ3 . TRP A 1 191 ? 123.687 97.660  77.127  1.00 300.82 ? 190 TRP A CZ3 1 
ATOM   236   C CH2 . TRP A 1 191 ? 122.786 97.349  76.106  1.00 326.71 ? 190 TRP A CH2 1 
ATOM   237   N N   . LEU A 1 192 ? 127.539 103.707 78.168  1.00 206.94 ? 191 LEU A N   1 
ATOM   238   C CA  . LEU A 1 192 ? 128.350 104.150 79.291  1.00 238.35 ? 191 LEU A CA  1 
ATOM   239   C C   . LEU A 1 192 ? 127.462 104.567 80.474  1.00 253.05 ? 191 LEU A C   1 
ATOM   240   O O   . LEU A 1 192 ? 127.743 104.167 81.600  1.00 296.43 ? 191 LEU A O   1 
ATOM   241   C CB  . LEU A 1 192 ? 129.262 105.289 78.817  1.00 334.69 ? 191 LEU A CB  1 
ATOM   242   C CG  . LEU A 1 192 ? 130.230 105.859 79.858  1.00 447.98 ? 191 LEU A CG  1 
ATOM   243   C CD1 . LEU A 1 192 ? 131.298 104.841 80.244  1.00 476.91 ? 191 LEU A CD1 1 
ATOM   244   C CD2 . LEU A 1 192 ? 130.881 107.134 79.344  1.00 515.20 ? 191 LEU A CD2 1 
ATOM   245   N N   . GLY A 1 193 ? 126.398 105.355 80.231  1.00 249.25 ? 192 GLY A N   1 
ATOM   246   C CA  . GLY A 1 193 ? 125.456 105.811 81.259  1.00 225.55 ? 192 GLY A CA  1 
ATOM   247   C C   . GLY A 1 193 ? 124.602 104.704 81.890  1.00 165.42 ? 192 GLY A C   1 
ATOM   248   O O   . GLY A 1 193 ? 124.358 104.702 83.096  1.00 192.67 ? 192 GLY A O   1 
ATOM   249   N N   . TRP A 1 194 ? 124.155 103.746 81.081  1.00 162.46 ? 193 TRP A N   1 
ATOM   250   C CA  . TRP A 1 194 ? 123.439 102.582 81.595  1.00 141.93 ? 193 TRP A CA  1 
ATOM   251   C C   . TRP A 1 194 ? 124.363 101.641 82.358  1.00 139.70 ? 193 TRP A C   1 
ATOM   252   O O   . TRP A 1 194 ? 123.929 101.152 83.397  1.00 226.48 ? 193 TRP A O   1 
ATOM   253   C CB  . TRP A 1 194 ? 122.822 101.881 80.422  1.00 167.06 ? 193 TRP A CB  1 
ATOM   254   C CG  . TRP A 1 194 ? 121.990 100.648 80.556  1.00 152.27 ? 193 TRP A CG  1 
ATOM   255   C CD1 . TRP A 1 194 ? 120.634 100.611 80.376  1.00 133.75 ? 193 TRP A CD1 1 
ATOM   256   C CD2 . TRP A 1 194 ? 122.443 99.295  80.767  1.00 122.81 ? 193 TRP A CD2 1 
ATOM   257   N NE1 . TRP A 1 194 ? 120.185 99.321  80.470  1.00 131.70 ? 193 TRP A NE1 1 
ATOM   258   C CE2 . TRP A 1 194 ? 121.267 98.491  80.716  1.00 165.99 ? 193 TRP A CE2 1 
ATOM   259   C CE3 . TRP A 1 194 ? 123.681 98.683  81.000  1.00 87.39  ? 193 TRP A CE3 1 
ATOM   260   C CZ2 . TRP A 1 194 ? 121.324 97.098  80.898  1.00 166.85 ? 193 TRP A CZ2 1 
ATOM   261   C CZ3 . TRP A 1 194 ? 123.716 97.310  81.182  1.00 179.81 ? 193 TRP A CZ3 1 
ATOM   262   C CH2 . TRP A 1 194 ? 122.557 96.523  81.112  1.00 175.04 ? 193 TRP A CH2 1 
ATOM   263   N N   . LEU A 1 195 ? 125.609 101.410 81.924  1.00 119.30 ? 194 LEU A N   1 
ATOM   264   C CA  . LEU A 1 195 ? 126.552 100.698 82.792  1.00 165.64 ? 194 LEU A CA  1 
ATOM   265   C C   . LEU A 1 195 ? 126.897 101.491 84.061  1.00 180.59 ? 194 LEU A C   1 
ATOM   266   O O   . LEU A 1 195 ? 127.140 100.883 85.104  1.00 162.50 ? 194 LEU A O   1 
ATOM   267   C CB  . LEU A 1 195 ? 127.812 100.339 82.008  1.00 201.99 ? 194 LEU A CB  1 
ATOM   268   C CG  . LEU A 1 195 ? 127.622 99.192  81.026  1.00 212.88 ? 194 LEU A CG  1 
ATOM   269   C CD1 . LEU A 1 195 ? 128.816 99.070  80.093  1.00 320.01 ? 194 LEU A CD1 1 
ATOM   270   C CD2 . LEU A 1 195 ? 127.399 97.891  81.771  1.00 149.63 ? 194 LEU A CD2 1 
ATOM   271   N N   . GLY A 1 196 ? 126.910 102.830 83.996  1.00 187.77 ? 195 GLY A N   1 
ATOM   272   C CA  . GLY A 1 196 ? 126.973 103.678 85.184  1.00 235.55 ? 195 GLY A CA  1 
ATOM   273   C C   . GLY A 1 196 ? 125.831 103.432 86.173  1.00 184.11 ? 195 GLY A C   1 
ATOM   274   O O   . GLY A 1 196 ? 126.078 103.311 87.365  1.00 167.42 ? 195 GLY A O   1 
ATOM   275   N N   . MET A 1 197 ? 124.599 103.354 85.672  1.00 179.23 ? 196 MET A N   1 
ATOM   276   C CA  . MET A 1 197 ? 123.421 103.069 86.484  1.00 139.09 ? 196 MET A CA  1 
ATOM   277   C C   . MET A 1 197 ? 123.465 101.619 86.987  1.00 115.13 ? 196 MET A C   1 
ATOM   278   O O   . MET A 1 197 ? 123.048 101.403 88.121  1.00 216.21 ? 196 MET A O   1 
ATOM   279   C CB  . MET A 1 197 ? 122.140 103.368 85.681  1.00 162.39 ? 196 MET A CB  1 
ATOM   280   C CG  . MET A 1 197 ? 120.809 102.766 86.196  1.00 172.85 ? 196 MET A CG  1 
ATOM   281   S SD  . MET A 1 197 ? 119.307 103.151 85.200  1.00 214.00 ? 196 MET A SD  1 
ATOM   282   C CE  . MET A 1 197 ? 118.989 104.877 85.635  1.00 215.18 ? 196 MET A CE  1 
ATOM   283   N N   . LEU A 1 198 ? 123.975 100.646 86.220  1.00 102.03 ? 197 LEU A N   1 
ATOM   284   C CA  . LEU A 1 198 ? 124.156 99.282  86.701  1.00 119.75 ? 197 LEU A CA  1 
ATOM   285   C C   . LEU A 1 198 ? 125.185 99.289  87.834  1.00 120.72 ? 197 LEU A C   1 
ATOM   286   O O   . LEU A 1 198 ? 124.926 98.696  88.885  1.00 131.30 ? 197 LEU A O   1 
ATOM   287   C CB  . LEU A 1 198 ? 124.556 98.385  85.524  1.00 151.91 ? 197 LEU A CB  1 
ATOM   288   C CG  . LEU A 1 198 ? 124.759 96.871  85.742  1.00 159.95 ? 197 LEU A CG  1 
ATOM   289   C CD1 . LEU A 1 198 ? 126.009 96.510  86.583  1.00 140.86 ? 197 LEU A CD1 1 
ATOM   290   C CD2 . LEU A 1 198 ? 123.508 96.237  86.323  1.00 188.34 ? 197 LEU A CD2 1 
ATOM   291   N N   . ALA A 1 199 ? 126.310 99.984  87.658  1.00 121.39 ? 198 ALA A N   1 
ATOM   292   C CA  . ALA A 1 199 ? 127.292 100.053 88.722  1.00 185.32 ? 198 ALA A CA  1 
ATOM   293   C C   . ALA A 1 199 ? 126.704 100.744 89.964  1.00 218.63 ? 198 ALA A C   1 
ATOM   294   O O   . ALA A 1 199 ? 126.956 100.266 91.083  1.00 306.79 ? 198 ALA A O   1 
ATOM   295   C CB  . ALA A 1 199 ? 128.531 100.743 88.205  1.00 259.58 ? 198 ALA A CB  1 
ATOM   296   N N   . GLY A 1 200 ? 125.927 101.840 89.780  1.00 199.27 ? 199 GLY A N   1 
ATOM   297   C CA  . GLY A 1 200 ? 125.228 102.549 90.855  1.00 197.35 ? 199 GLY A CA  1 
ATOM   298   C C   . GLY A 1 200 ? 124.316 101.624 91.670  1.00 178.01 ? 199 GLY A C   1 
ATOM   299   O O   . GLY A 1 200 ? 124.380 101.570 92.888  1.00 191.30 ? 199 GLY A O   1 
ATOM   300   N N   . ALA A 1 201 ? 123.473 100.874 90.980  1.00 165.38 ? 200 ALA A N   1 
ATOM   301   C CA  . ALA A 1 201 ? 122.596 99.930  91.631  1.00 150.57 ? 200 ALA A CA  1 
ATOM   302   C C   . ALA A 1 201 ? 123.423 98.862  92.344  1.00 156.89 ? 200 ALA A C   1 
ATOM   303   O O   . ALA A 1 201 ? 123.072 98.516  93.460  1.00 223.75 ? 200 ALA A O   1 
ATOM   304   C CB  . ALA A 1 201 ? 121.629 99.356  90.599  1.00 167.61 ? 200 ALA A CB  1 
ATOM   305   N N   . VAL A 1 202 ? 124.492 98.306  91.740  1.00 119.40 ? 201 VAL A N   1 
ATOM   306   C CA  . VAL A 1 202 ? 125.271 97.263  92.402  1.00 158.22 ? 201 VAL A CA  1 
ATOM   307   C C   . VAL A 1 202 ? 125.994 97.810  93.641  1.00 169.12 ? 201 VAL A C   1 
ATOM   308   O O   . VAL A 1 202 ? 126.044 97.095  94.647  1.00 260.64 ? 201 VAL A O   1 
ATOM   309   C CB  . VAL A 1 202 ? 126.197 96.527  91.437  1.00 188.40 ? 201 VAL A CB  1 
ATOM   310   C CG1 . VAL A 1 202 ? 127.286 95.709  92.122  1.00 235.55 ? 201 VAL A CG1 1 
ATOM   311   C CG2 . VAL A 1 202 ? 125.332 95.633  90.546  1.00 219.54 ? 201 VAL A CG2 1 
ATOM   312   N N   . VAL A 1 203 ? 126.483 99.044  93.610  1.00 151.52 ? 202 VAL A N   1 
ATOM   313   C CA  . VAL A 1 203 ? 126.993 99.687  94.823  1.00 177.74 ? 202 VAL A CA  1 
ATOM   314   C C   . VAL A 1 203 ? 125.926 99.724  95.928  1.00 177.89 ? 202 VAL A C   1 
ATOM   315   O O   . VAL A 1 203 ? 126.236 99.324  97.046  1.00 215.82 ? 202 VAL A O   1 
ATOM   316   C CB  . VAL A 1 203 ? 127.559 101.098 94.507  1.00 266.50 ? 202 VAL A CB  1 
ATOM   317   C CG1 . VAL A 1 203 ? 127.579 102.109 95.672  1.00 231.60 ? 202 VAL A CG1 1 
ATOM   318   C CG2 . VAL A 1 203 ? 128.942 100.952 93.888  1.00 306.68 ? 202 VAL A CG2 1 
ATOM   319   N N   . ILE A 1 204 ? 124.699 100.204 95.644  1.00 150.40 ? 203 ILE A N   1 
ATOM   320   C CA  . ILE A 1 204 ? 123.640 100.319 96.645  1.00 142.82 ? 203 ILE A CA  1 
ATOM   321   C C   . ILE A 1 204 ? 123.342 98.952  97.255  1.00 126.59 ? 203 ILE A C   1 
ATOM   322   O O   . ILE A 1 204 ? 123.257 98.835  98.467  1.00 201.99 ? 203 ILE A O   1 
ATOM   323   C CB  . ILE A 1 204 ? 122.394 101.021 96.062  1.00 141.81 ? 203 ILE A CB  1 
ATOM   324   C CG1 . ILE A 1 204 ? 122.738 102.489 95.780  1.00 200.51 ? 203 ILE A CG1 1 
ATOM   325   C CG2 . ILE A 1 204 ? 121.184 100.931 96.957  1.00 161.32 ? 203 ILE A CG2 1 
ATOM   326   C CD1 . ILE A 1 204 ? 121.677 103.266 95.051  1.00 215.42 ? 203 ILE A CD1 1 
ATOM   327   N N   . ILE A 1 205 ? 123.190 97.927  96.431  1.00 93.98  ? 204 ILE A N   1 
ATOM   328   C CA  . ILE A 1 205 ? 122.929 96.576  96.913  1.00 109.59 ? 204 ILE A CA  1 
ATOM   329   C C   . ILE A 1 205 ? 124.115 95.995  97.726  1.00 174.10 ? 204 ILE A C   1 
ATOM   330   O O   . ILE A 1 205 ? 123.882 95.170  98.621  1.00 269.53 ? 204 ILE A O   1 
ATOM   331   C CB  . ILE A 1 205 ? 122.572 95.699  95.689  1.00 153.63 ? 204 ILE A CB  1 
ATOM   332   C CG1 . ILE A 1 205 ? 121.292 96.225  94.988  1.00 127.97 ? 204 ILE A CG1 1 
ATOM   333   C CG2 . ILE A 1 205 ? 122.569 94.180  95.991  1.00 126.13 ? 204 ILE A CG2 1 
ATOM   334   C CD1 . ILE A 1 205 ? 120.031 96.062  95.747  1.00 175.31 ? 204 ILE A CD1 1 
ATOM   335   N N   . VAL A 1 206 ? 125.372 96.398  97.451  1.00 132.82 ? 205 VAL A N   1 
ATOM   336   C CA  . VAL A 1 206 ? 126.515 95.950  98.252  1.00 197.69 ? 205 VAL A CA  1 
ATOM   337   C C   . VAL A 1 206 ? 126.611 96.689  99.598  1.00 212.90 ? 205 VAL A C   1 
ATOM   338   O O   . VAL A 1 206 ? 126.918 96.030  100.598 1.00 210.04 ? 205 VAL A O   1 
ATOM   339   C CB  . VAL A 1 206 ? 127.828 96.020  97.444  1.00 285.97 ? 205 VAL A CB  1 
ATOM   340   C CG1 . VAL A 1 206 ? 129.103 95.994  98.292  1.00 296.27 ? 205 VAL A CG1 1 
ATOM   341   C CG2 . VAL A 1 206 ? 127.851 94.886  96.430  1.00 330.40 ? 205 VAL A CG2 1 
ATOM   342   N N   . ARG A 1 207 ? 126.370 98.018  99.657  1.00 181.43 ? 206 ARG A N   1 
ATOM   343   C CA  . ARG A 1 207 ? 126.552 98.768  100.906 1.00 218.30 ? 206 ARG A CA  1 
ATOM   344   C C   . ARG A 1 207 ? 125.276 98.906  101.756 1.00 245.71 ? 206 ARG A C   1 
ATOM   345   O O   . ARG A 1 207 ? 125.376 99.334  102.913 1.00 315.58 ? 206 ARG A O   1 
ATOM   346   C CB  . ARG A 1 207 ? 127.199 100.132 100.641 1.00 230.53 ? 206 ARG A CB  1 
ATOM   347   C CG  . ARG A 1 207 ? 126.341 101.225 100.008 1.00 239.73 ? 206 ARG A CG  1 
ATOM   348   C CD  . ARG A 1 207 ? 127.059 102.575 100.058 1.00 289.19 ? 206 ARG A CD  1 
ATOM   349   N NE  . ARG A 1 207 ? 128.333 102.590 99.324  1.00 370.56 ? 206 ARG A NE  1 
ATOM   350   C CZ  . ARG A 1 207 ? 129.046 103.672 98.997  1.00 359.05 ? 206 ARG A CZ  1 
ATOM   351   N NH1 . ARG A 1 207 ? 130.220 103.538 98.396  1.00 314.08 ? 206 ARG A NH1 1 
ATOM   352   N NH2 . ARG A 1 207 ? 128.602 104.887 99.278  1.00 325.11 ? 206 ARG A NH2 1 
ATOM   353   N N   . ALA A 1 208 ? 124.089 98.556  101.230 1.00 225.27 ? 207 ALA A N   1 
ATOM   354   C CA  . ALA A 1 208 ? 122.882 98.433  102.039 1.00 231.71 ? 207 ALA A CA  1 
ATOM   355   C C   . ALA A 1 208 ? 123.053 97.390  103.159 1.00 203.40 ? 207 ALA A C   1 
ATOM   356   O O   . ALA A 1 208 ? 123.691 96.355  102.973 1.00 158.15 ? 207 ALA A O   1 
ATOM   357   C CB  . ALA A 1 208 ? 121.707 98.098  101.145 1.00 242.93 ? 207 ALA A CB  1 
ATOM   358   N N   . PRO A 1 209 ? 122.483 97.626  104.368 1.00 178.41 ? 208 PRO A N   1 
ATOM   359   C CA  . PRO A 1 209 ? 122.678 96.719  105.508 1.00 187.27 ? 208 PRO A CA  1 
ATOM   360   C C   . PRO A 1 209 ? 121.931 95.391  105.366 1.00 155.00 ? 208 PRO A C   1 
ATOM   361   O O   . PRO A 1 209 ? 120.729 95.413  105.102 1.00 100.24 ? 208 PRO A O   1 
ATOM   362   C CB  . PRO A 1 209 ? 122.088 97.515  106.682 1.00 262.27 ? 208 PRO A CB  1 
ATOM   363   C CG  . PRO A 1 209 ? 121.052 98.453  106.048 1.00 229.77 ? 208 PRO A CG  1 
ATOM   364   C CD  . PRO A 1 209 ? 121.621 98.780  104.687 1.00 182.10 ? 208 PRO A CD  1 
ATOM   365   N N   . ARG A 1 210 ? 122.638 94.257  105.522 1.00 154.27 ? 209 ARG A N   1 
ATOM   366   C CA  . ARG A 1 210 ? 122.047 92.939  105.285 1.00 188.22 ? 209 ARG A CA  1 
ATOM   367   C C   . ARG A 1 210 ? 121.146 92.539  106.452 1.00 150.15 ? 209 ARG A C   1 
ATOM   368   O O   . ARG A 1 210 ? 121.414 92.947  107.573 1.00 178.67 ? 209 ARG A O   1 
ATOM   369   C CB  . ARG A 1 210 ? 123.149 91.907  104.993 1.00 215.56 ? 209 ARG A CB  1 
ATOM   370   C CG  . ARG A 1 210 ? 123.938 92.174  103.708 1.00 239.69 ? 209 ARG A CG  1 
ATOM   371   C CD  . ARG A 1 210 ? 123.093 92.183  102.438 1.00 256.15 ? 209 ARG A CD  1 
ATOM   372   N NE  . ARG A 1 210 ? 123.742 92.697  101.232 1.00 266.68 ? 209 ARG A NE  1 
ATOM   373   C CZ  . ARG A 1 210 ? 124.582 92.029  100.449 1.00 350.34 ? 209 ARG A CZ  1 
ATOM   374   N NH1 . ARG A 1 210 ? 124.996 92.574  99.315  1.00 370.57 ? 209 ARG A NH1 1 
ATOM   375   N NH2 . ARG A 1 210 ? 124.997 90.811  100.767 1.00 353.23 ? 209 ARG A NH2 1 
ATOM   376   N N   . CYS A 1 211 ? 120.094 91.747  106.170 1.00 161.54 ? 210 CYS A N   1 
ATOM   377   C CA  . CYS A 1 211 ? 119.131 91.307  107.177 1.00 192.48 ? 210 CYS A CA  1 
ATOM   378   C C   . CYS A 1 211 ? 119.794 90.459  108.273 1.00 237.40 ? 210 CYS A C   1 
ATOM   379   O O   . CYS A 1 211 ? 120.626 89.609  107.964 1.00 264.11 ? 210 CYS A O   1 
ATOM   380   C CB  . CYS A 1 211 ? 118.007 90.452  106.585 1.00 150.69 ? 210 CYS A CB  1 
ATOM   381   S SG  . CYS A 1 211 ? 117.118 91.184  105.192 1.00 189.47 ? 210 CYS A SG  1 
ATOM   382   N N   . ARG A 1 212 ? 119.429 90.682  109.554 1.00 209.55 ? 211 ARG A N   1 
ATOM   383   C CA  . ARG A 1 212 ? 119.817 89.778  110.628 1.00 162.05 ? 211 ARG A CA  1 
ATOM   384   C C   . ARG A 1 212 ? 119.098 88.445  110.383 1.00 166.58 ? 211 ARG A C   1 
ATOM   385   O O   . ARG A 1 212 ? 117.916 88.443  110.015 1.00 131.73 ? 211 ARG A O   1 
ATOM   386   C CB  . ARG A 1 212 ? 119.470 90.403  111.992 1.00 193.15 ? 211 ARG A CB  1 
ATOM   387   C CG  . ARG A 1 212 ? 119.754 89.529  113.217 1.00 261.03 ? 211 ARG A CG  1 
ATOM   388   C CD  . ARG A 1 212 ? 119.175 90.113  114.467 1.00 206.03 ? 211 ARG A CD  1 
ATOM   389   N NE  . ARG A 1 212 ? 119.735 91.287  115.031 1.00 200.39 ? 211 ARG A NE  1 
ATOM   390   C CZ  . ARG A 1 212 ? 120.801 91.278  115.799 1.00 253.36 ? 211 ARG A CZ  1 
ATOM   391   N NH1 . ARG A 1 212 ? 121.395 92.413  116.158 1.00 337.37 ? 211 ARG A NH1 1 
ATOM   392   N NH2 . ARG A 1 212 ? 121.288 90.125  116.228 1.00 248.02 ? 211 ARG A NH2 1 
ATOM   393   N N   . GLU A 1 213 ? 119.795 87.311  110.581 1.00 146.52 ? 212 GLU A N   1 
ATOM   394   C CA  . GLU A 1 213 ? 119.170 85.996  110.379 1.00 184.49 ? 212 GLU A CA  1 
ATOM   395   C C   . GLU A 1 213 ? 118.148 85.724  111.487 1.00 126.05 ? 212 GLU A C   1 
ATOM   396   O O   . GLU A 1 213 ? 118.305 86.191  112.608 1.00 218.13 ? 212 GLU A O   1 
ATOM   397   C CB  . GLU A 1 213 ? 120.226 84.882  110.240 1.00 228.64 ? 212 GLU A CB  1 
ATOM   398   C CG  . GLU A 1 213 ? 121.022 84.528  111.497 1.00 279.70 ? 212 GLU A CG  1 
ATOM   399   C CD  . GLU A 1 213 ? 122.128 85.476  111.953 1.00 362.93 ? 212 GLU A CD  1 
ATOM   400   O OE1 . GLU A 1 213 ? 122.334 86.534  111.305 1.00 348.05 ? 212 GLU A OE1 1 
ATOM   401   O OE2 . GLU A 1 213 ? 122.782 85.159  112.968 1.00 451.59 ? 212 GLU A OE2 1 
ATOM   402   N N   . LEU A 1 214 ? 117.092 84.956  111.196 1.00 124.71 ? 213 LEU A N   1 
ATOM   403   C CA  . LEU A 1 214 ? 116.040 84.725  112.182 1.00 126.34 ? 213 LEU A CA  1 
ATOM   404   C C   . LEU A 1 214 ? 116.419 83.722  113.265 1.00 170.17 ? 213 LEU A C   1 
ATOM   405   O O   . LEU A 1 214 ? 116.680 82.556  113.238 1.00 199.07 ? 213 LEU A O   1 
ATOM   406   C CB  . LEU A 1 214 ? 114.804 84.079  111.581 1.00 140.06 ? 213 LEU A CB  1 
ATOM   407   C CG  . LEU A 1 214 ? 114.083 84.856  110.496 1.00 198.06 ? 213 LEU A CG  1 
ATOM   408   C CD1 . LEU A 1 214 ? 112.889 84.069  109.968 1.00 308.49 ? 213 LEU A CD1 1 
ATOM   409   C CD2 . LEU A 1 214 ? 113.627 86.143  111.049 1.00 115.32 ? 213 LEU A CD2 1 
ATOM   410   N N   . PRO A 1 215 ? 116.293 83.881  114.518 1.00 161.27 ? 214 PRO A N   1 
ATOM   411   C CA  . PRO A 1 215 ? 116.633 82.662  115.257 1.00 159.12 ? 214 PRO A CA  1 
ATOM   412   C C   . PRO A 1 215 ? 115.632 81.507  115.041 1.00 164.74 ? 214 PRO A C   1 
ATOM   413   O O   . PRO A 1 215 ? 114.441 81.714  114.794 1.00 136.03 ? 214 PRO A O   1 
ATOM   414   C CB  . PRO A 1 215 ? 116.626 83.285  116.589 1.00 232.82 ? 214 PRO A CB  1 
ATOM   415   C CG  . PRO A 1 215 ? 115.582 84.367  116.504 1.00 230.11 ? 214 PRO A CG  1 
ATOM   416   C CD  . PRO A 1 215 ? 115.793 85.024  115.196 1.00 159.77 ? 214 PRO A CD  1 
ATOM   417   N N   . ALA A 1 216 ? 116.143 80.266  115.082 1.00 233.63 ? 215 ALA A N   1 
ATOM   418   C CA  . ALA A 1 216 ? 115.303 79.095  114.908 1.00 262.68 ? 215 ALA A CA  1 
ATOM   419   C C   . ALA A 1 216 ? 114.537 78.991  116.207 1.00 191.09 ? 215 ALA A C   1 
ATOM   420   O O   . ALA A 1 216 ? 115.163 78.820  117.240 1.00 153.68 ? 215 ALA A O   1 
ATOM   421   C CB  . ALA A 1 216 ? 116.093 77.837  114.659 1.00 323.35 ? 215 ALA A CB  1 
ATOM   422   N N   . GLN A 1 217 ? 113.229 79.152  116.144 1.00 146.51 ? 216 GLN A N   1 
ATOM   423   C CA  . GLN A 1 217 ? 112.466 79.318  117.373 1.00 146.19 ? 216 GLN A CA  1 
ATOM   424   C C   . GLN A 1 217 ? 111.657 78.040  117.612 1.00 146.33 ? 216 GLN A C   1 
ATOM   425   O O   . GLN A 1 217 ? 110.892 77.586  116.758 1.00 118.43 ? 216 GLN A O   1 
ATOM   426   C CB  . GLN A 1 217 ? 111.637 80.598  117.302 1.00 164.35 ? 216 GLN A CB  1 
ATOM   427   C CG  . GLN A 1 217 ? 110.680 80.665  116.113 1.00 204.35 ? 216 GLN A CG  1 
ATOM   428   C CD  . GLN A 1 217 ? 109.896 81.957  116.152 1.00 291.88 ? 216 GLN A CD  1 
ATOM   429   O OE1 . GLN A 1 217 ? 109.884 82.660  117.175 1.00 212.92 ? 216 GLN A OE1 1 
ATOM   430   N NE2 . GLN A 1 217 ? 109.249 82.284  115.036 1.00 350.42 ? 216 GLN A NE2 1 
ATOM   431   N N   . LYS A 1 218 ? 111.841 77.496  118.819 1.00 149.58 ? 217 LYS A N   1 
ATOM   432   C CA  . LYS A 1 218 ? 111.066 76.382  119.339 1.00 129.05 ? 217 LYS A CA  1 
ATOM   433   C C   . LYS A 1 218 ? 109.622 76.812  119.489 1.00 100.88 ? 217 LYS A C   1 
ATOM   434   O O   . LYS A 1 218 ? 109.328 77.980  119.578 1.00 136.59 ? 217 LYS A O   1 
ATOM   435   C CB  . LYS A 1 218 ? 111.719 75.950  120.667 1.00 154.47 ? 217 LYS A CB  1 
ATOM   436   C CG  . LYS A 1 218 ? 113.200 75.551  120.553 1.00 179.95 ? 217 LYS A CG  1 
ATOM   437   C CD  . LYS A 1 218 ? 113.433 74.718  119.287 1.00 230.80 ? 217 LYS A CD  1 
ATOM   438   C CE  . LYS A 1 218 ? 114.690 73.899  119.150 1.00 267.25 ? 217 LYS A CE  1 
ATOM   439   N NZ  . LYS A 1 218 ? 114.677 73.259  117.810 1.00 318.75 ? 217 LYS A NZ  1 
ATOM   440   N N   . TRP A 1 219 ? 108.705 75.884  119.541 1.00 92.33  ? 218 TRP A N   1 
ATOM   441   C CA  . TRP A 1 219 ? 107.305 76.293  119.571 1.00 93.83  ? 218 TRP A CA  1 
ATOM   442   C C   . TRP A 1 219 ? 106.895 77.147  120.754 1.00 84.61  ? 218 TRP A C   1 
ATOM   443   O O   . TRP A 1 219 ? 106.142 78.099  120.611 1.00 105.10 ? 218 TRP A O   1 
ATOM   444   C CB  . TRP A 1 219 ? 106.391 75.090  119.553 1.00 115.57 ? 218 TRP A CB  1 
ATOM   445   C CG  . TRP A 1 219 ? 106.580 74.066  120.613 1.00 73.97  ? 218 TRP A CG  1 
ATOM   446   C CD1 . TRP A 1 219 ? 107.298 72.910  120.535 1.00 130.49 ? 218 TRP A CD1 1 
ATOM   447   C CD2 . TRP A 1 219 ? 105.950 74.056  121.879 1.00 67.65  ? 218 TRP A CD2 1 
ATOM   448   N NE1 . TRP A 1 219 ? 107.193 72.194  121.691 1.00 113.66 ? 218 TRP A NE1 1 
ATOM   449   C CE2 . TRP A 1 219 ? 106.358 72.879  122.523 1.00 96.89  ? 218 TRP A CE2 1 
ATOM   450   C CE3 . TRP A 1 219 ? 105.090 74.915  122.531 1.00 73.22  ? 218 TRP A CE3 1 
ATOM   451   C CZ2 . TRP A 1 219 ? 105.919 72.559  123.797 1.00 136.25 ? 218 TRP A CZ2 1 
ATOM   452   C CZ3 . TRP A 1 219 ? 104.646 74.582  123.781 1.00 108.81 ? 218 TRP A CZ3 1 
ATOM   453   C CH2 . TRP A 1 219 ? 105.054 73.431  124.401 1.00 97.37  ? 218 TRP A CH2 1 
ATOM   454   N N   . TRP A 1 220 ? 107.480 76.872  121.900 1.00 92.55  ? 219 TRP A N   1 
ATOM   455   C CA  . TRP A 1 220 ? 107.189 77.663  123.087 1.00 77.44  ? 219 TRP A CA  1 
ATOM   456   C C   . TRP A 1 220 ? 107.780 79.085  123.074 1.00 55.46  ? 219 TRP A C   1 
ATOM   457   O O   . TRP A 1 220 ? 107.423 79.890  123.916 1.00 74.17  ? 219 TRP A O   1 
ATOM   458   C CB  . TRP A 1 220 ? 107.666 76.899  124.329 1.00 73.04  ? 219 TRP A CB  1 
ATOM   459   C CG  . TRP A 1 220 ? 109.140 76.706  124.473 1.00 71.83  ? 219 TRP A CG  1 
ATOM   460   C CD1 . TRP A 1 220 ? 110.006 77.559  125.042 1.00 90.50  ? 219 TRP A CD1 1 
ATOM   461   C CD2 . TRP A 1 220 ? 109.910 75.564  124.066 1.00 81.83  ? 219 TRP A CD2 1 
ATOM   462   N NE1 . TRP A 1 220 ? 111.263 77.018  125.032 1.00 125.97 ? 219 TRP A NE1 1 
ATOM   463   C CE2 . TRP A 1 220 ? 111.230 75.801  124.438 1.00 87.89  ? 219 TRP A CE2 1 
ATOM   464   C CE3 . TRP A 1 220 ? 109.604 74.363  123.429 1.00 94.04  ? 219 TRP A CE3 1 
ATOM   465   C CZ2 . TRP A 1 220 ? 112.244 74.890  124.183 1.00 163.91 ? 219 TRP A CZ2 1 
ATOM   466   C CZ3 . TRP A 1 220 ? 110.586 73.447  123.174 1.00 111.37 ? 219 TRP A CZ3 1 
ATOM   467   C CH2 . TRP A 1 220 ? 111.901 73.716  123.549 1.00 161.15 ? 219 TRP A CH2 1 
ATOM   468   N N   . HIS A 1 221 ? 108.677 79.436  122.164 1.00 50.61  ? 220 HIS A N   1 
ATOM   469   C CA  . HIS A 1 221 ? 108.881 80.847  121.962 1.00 74.25  ? 220 HIS A CA  1 
ATOM   470   C C   . HIS A 1 221 ? 107.688 81.582  121.348 1.00 68.92  ? 220 HIS A C   1 
ATOM   471   O O   . HIS A 1 221 ? 107.549 82.769  121.600 1.00 118.17 ? 220 HIS A O   1 
ATOM   472   C CB  . HIS A 1 221 ? 110.112 81.155  121.108 1.00 117.86 ? 220 HIS A CB  1 
ATOM   473   C CG  . HIS A 1 221 ? 111.385 80.604  121.682 1.00 124.27 ? 220 HIS A CG  1 
ATOM   474   N ND1 . HIS A 1 221 ? 112.603 80.870  121.089 1.00 155.85 ? 220 HIS A ND1 1 
ATOM   475   C CD2 . HIS A 1 221 ? 111.612 79.826  122.778 1.00 67.23  ? 220 HIS A CD2 1 
ATOM   476   C CE1 . HIS A 1 221 ? 113.526 80.246  121.830 1.00 192.49 ? 220 HIS A CE1 1 
ATOM   477   N NE2 . HIS A 1 221 ? 112.945 79.595  122.845 1.00 94.51  ? 220 HIS A NE2 1 
ATOM   478   N N   . THR A 1 222 ? 106.830 80.935  120.590 1.00 66.84  ? 221 THR A N   1 
ATOM   479   C CA  . THR A 1 222 ? 105.921 81.649  119.724 1.00 70.97  ? 221 THR A CA  1 
ATOM   480   C C   . THR A 1 222 ? 104.664 82.150  120.434 1.00 91.32  ? 221 THR A C   1 
ATOM   481   O O   . THR A 1 222 ? 103.791 82.683  119.726 1.00 116.69 ? 221 THR A O   1 
ATOM   482   C CB  . THR A 1 222 ? 105.482 80.782  118.537 1.00 126.24 ? 221 THR A CB  1 
ATOM   483   O OG1 . THR A 1 222 ? 104.748 79.635  118.981 1.00 111.52 ? 221 THR A OG1 1 
ATOM   484   C CG2 . THR A 1 222 ? 106.667 80.330  117.704 1.00 208.29 ? 221 THR A CG2 1 
ATOM   485   N N   . GLY A 1 223 ? 104.544 82.025  121.785 1.00 88.30  ? 222 GLY A N   1 
ATOM   486   C CA  . GLY A 1 223 ? 103.438 82.653  122.519 1.00 80.50  ? 222 GLY A CA  1 
ATOM   487   C C   . GLY A 1 223 ? 103.105 81.882  123.772 1.00 86.19  ? 222 GLY A C   1 
ATOM   488   O O   . GLY A 1 223 ? 103.892 80.981  124.155 1.00 100.06 ? 222 GLY A O   1 
ATOM   489   N N   . ALA A 1 224 ? 101.950 82.236  124.366 1.00 61.63  ? 223 ALA A N   1 
ATOM   490   C CA  . ALA A 1 224 ? 101.724 81.895  125.775 1.00 72.95  ? 223 ALA A CA  1 
ATOM   491   C C   . ALA A 1 224 ? 101.441 80.401  126.050 1.00 60.92  ? 223 ALA A C   1 
ATOM   492   O O   . ALA A 1 224 ? 100.643 79.803  125.386 1.00 89.34  ? 223 ALA A O   1 
ATOM   493   C CB  . ALA A 1 224 ? 100.602 82.761  126.250 1.00 83.23  ? 223 ALA A CB  1 
ATOM   494   N N   . LEU A 1 225 ? 102.020 79.788  127.074 1.00 46.69  ? 224 LEU A N   1 
ATOM   495   C CA  . LEU A 1 225 ? 101.487 78.545  127.631 1.00 54.07  ? 224 LEU A CA  1 
ATOM   496   C C   . LEU A 1 225 ? 100.319 78.839  128.571 1.00 51.86  ? 224 LEU A C   1 
ATOM   497   O O   . LEU A 1 225 ? 99.930  79.981  128.738 1.00 63.07  ? 224 LEU A O   1 
ATOM   498   C CB  . LEU A 1 225 ? 102.525 77.796  128.444 1.00 68.95  ? 224 LEU A CB  1 
ATOM   499   C CG  . LEU A 1 225 ? 103.887 77.688  127.810 1.00 75.16  ? 224 LEU A CG  1 
ATOM   500   C CD1 . LEU A 1 225 ? 104.776 76.770  128.592 1.00 94.21  ? 224 LEU A CD1 1 
ATOM   501   C CD2 . LEU A 1 225 ? 103.725 77.173  126.466 1.00 82.71  ? 224 LEU A CD2 1 
ATOM   502   N N   . TYR A 1 226 ? 99.715  77.802  129.179 1.00 60.67  ? 225 TYR A N   1 
ATOM   503   C CA  . TYR A 1 226 ? 98.406  77.902  129.827 1.00 58.90  ? 225 TYR A CA  1 
ATOM   504   C C   . TYR A 1 226 ? 98.195  76.663  130.697 1.00 48.65  ? 225 TYR A C   1 
ATOM   505   O O   . TYR A 1 226 ? 98.140  75.574  130.180 1.00 63.42  ? 225 TYR A O   1 
ATOM   506   C CB  . TYR A 1 226 ? 97.261  78.078  128.815 1.00 50.39  ? 225 TYR A CB  1 
ATOM   507   C CG  . TYR A 1 226 ? 95.890  78.407  129.378 1.00 67.51  ? 225 TYR A CG  1 
ATOM   508   C CD1 . TYR A 1 226 ? 95.175  77.443  130.090 1.00 62.79  ? 225 TYR A CD1 1 
ATOM   509   C CD2 . TYR A 1 226 ? 95.360  79.698  129.246 1.00 87.29  ? 225 TYR A CD2 1 
ATOM   510   C CE1 . TYR A 1 226 ? 93.941  77.751  130.642 1.00 93.26  ? 225 TYR A CE1 1 
ATOM   511   C CE2 . TYR A 1 226 ? 94.129  80.009  129.795 1.00 92.61  ? 225 TYR A CE2 1 
ATOM   512   C CZ  . TYR A 1 226 ? 93.416  79.037  130.481 1.00 90.22  ? 225 TYR A CZ  1 
ATOM   513   O OH  . TYR A 1 226 ? 92.196  79.284  131.047 1.00 73.67  ? 225 TYR A OH  1 
ATOM   514   N N   . ARG A 1 227 ? 98.061  76.826  131.993 1.00 40.51  ? 226 ARG A N   1 
ATOM   515   C CA  . ARG A 1 227 ? 98.115  75.673  132.855 1.00 65.98  ? 226 ARG A CA  1 
ATOM   516   C C   . ARG A 1 227 ? 96.757  75.320  133.449 1.00 62.22  ? 226 ARG A C   1 
ATOM   517   O O   . ARG A 1 227 ? 96.020  76.201  133.880 1.00 80.85  ? 226 ARG A O   1 
ATOM   518   C CB  . ARG A 1 227 ? 99.025  75.929  134.056 1.00 86.46  ? 226 ARG A CB  1 
ATOM   519   C CG  . ARG A 1 227 ? 100.405 76.358  133.618 1.00 101.11 ? 226 ARG A CG  1 
ATOM   520   C CD  . ARG A 1 227 ? 101.263 76.549  134.858 1.00 123.69 ? 226 ARG A CD  1 
ATOM   521   N NE  . ARG A 1 227 ? 100.951 77.784  135.484 1.00 79.91  ? 226 ARG A NE  1 
ATOM   522   C CZ  . ARG A 1 227 ? 101.827 78.538  136.078 1.00 99.17  ? 226 ARG A CZ  1 
ATOM   523   N NH1 . ARG A 1 227 ? 101.403 79.688  136.583 1.00 136.46 ? 226 ARG A NH1 1 
ATOM   524   N NH2 . ARG A 1 227 ? 103.099 78.123  136.157 1.00 108.98 ? 226 ARG A NH2 1 
ATOM   525   N N   . ILE A 1 228 ? 96.507  74.013  133.507 1.00 60.77  ? 227 ILE A N   1 
ATOM   526   C CA  . ILE A 1 228 ? 95.245  73.474  133.932 1.00 64.88  ? 227 ILE A CA  1 
ATOM   527   C C   . ILE A 1 228 ? 95.491  72.527  135.080 1.00 69.04  ? 227 ILE A C   1 
ATOM   528   O O   . ILE A 1 228 ? 95.641  71.325  134.877 1.00 87.51  ? 227 ILE A O   1 
ATOM   529   C CB  . ILE A 1 228 ? 94.572  72.866  132.690 1.00 59.95  ? 227 ILE A CB  1 
ATOM   530   C CG1 . ILE A 1 228 ? 94.402  74.013  131.683 1.00 60.59  ? 227 ILE A CG1 1 
ATOM   531   C CG2 . ILE A 1 228 ? 93.274  72.193  133.141 1.00 73.07  ? 227 ILE A CG2 1 
ATOM   532   C CD1 . ILE A 1 228 ? 93.346  73.808  130.652 1.00 75.50  ? 227 ILE A CD1 1 
ATOM   533   N N   . GLY A 1 229 ? 95.571  73.098  136.287 1.00 109.99 ? 228 GLY A N   1 
ATOM   534   C CA  . GLY A 1 229 ? 96.032  72.361  137.454 1.00 157.33 ? 228 GLY A CA  1 
ATOM   535   C C   . GLY A 1 229 ? 95.014  71.327  137.925 1.00 192.12 ? 228 GLY A C   1 
ATOM   536   O O   . GLY A 1 229 ? 95.438  70.317  138.523 1.00 313.18 ? 228 GLY A O   1 
ATOM   537   N N   . ASP A 1 230 ? 93.703  71.565  137.661 1.00 132.20 ? 229 ASP A N   1 
ATOM   538   C CA  . ASP A 1 230 ? 92.721  70.521  137.925 1.00 180.28 ? 229 ASP A CA  1 
ATOM   539   C C   . ASP A 1 230 ? 91.656  70.531  136.850 1.00 145.90 ? 229 ASP A C   1 
ATOM   540   O O   . ASP A 1 230 ? 90.907  71.477  136.775 1.00 155.10 ? 229 ASP A O   1 
ATOM   541   C CB  . ASP A 1 230 ? 92.121  70.585  139.339 1.00 188.76 ? 229 ASP A CB  1 
ATOM   542   C CG  . ASP A 1 230 ? 91.355  69.315  139.748 1.00 286.29 ? 229 ASP A CG  1 
ATOM   543   O OD1 . ASP A 1 230 ? 90.835  68.588  138.853 1.00 313.96 ? 229 ASP A OD1 1 
ATOM   544   O OD2 . ASP A 1 230 ? 91.257  69.035  140.959 1.00 337.09 ? 229 ASP A OD2 1 
ATOM   545   N N   . LEU A 1 231 ? 91.624  69.422  136.088 1.00 123.97 ? 230 LEU A N   1 
ATOM   546   C CA  . LEU A 1 231 ? 90.672  69.169  135.026 1.00 111.12 ? 230 LEU A CA  1 
ATOM   547   C C   . LEU A 1 231 ? 89.227  69.328  135.485 1.00 136.38 ? 230 LEU A C   1 
ATOM   548   O O   . LEU A 1 231 ? 88.395  69.710  134.659 1.00 140.19 ? 230 LEU A O   1 
ATOM   549   C CB  . LEU A 1 231 ? 90.935  67.753  134.533 1.00 97.44  ? 230 LEU A CB  1 
ATOM   550   C CG  . LEU A 1 231 ? 92.145  67.656  133.628 1.00 149.29 ? 230 LEU A CG  1 
ATOM   551   C CD1 . LEU A 1 231 ? 92.579  66.201  133.417 1.00 193.03 ? 230 LEU A CD1 1 
ATOM   552   C CD2 . LEU A 1 231 ? 91.825  68.387  132.327 1.00 131.29 ? 230 LEU A CD2 1 
ATOM   553   N N   . GLN A 1 232 ? 88.955  69.012  136.764 1.00 135.77 ? 231 GLN A N   1 
ATOM   554   C CA  . GLN A 1 232 ? 87.596  69.023  137.302 1.00 154.11 ? 231 GLN A CA  1 
ATOM   555   C C   . GLN A 1 232 ? 87.168  70.459  137.505 1.00 115.32 ? 231 GLN A C   1 
ATOM   556   O O   . GLN A 1 232 ? 86.092  70.841  137.062 1.00 112.13 ? 231 GLN A O   1 
ATOM   557   C CB  . GLN A 1 232 ? 87.473  68.190  138.580 1.00 167.33 ? 231 GLN A CB  1 
ATOM   558   C CG  . GLN A 1 232 ? 87.662  66.702  138.296 1.00 228.46 ? 231 GLN A CG  1 
ATOM   559   C CD  . GLN A 1 232 ? 88.249  65.919  139.449 1.00 343.49 ? 231 GLN A CD  1 
ATOM   560   O OE1 . GLN A 1 232 ? 87.660  64.939  139.901 1.00 363.33 ? 231 GLN A OE1 1 
ATOM   561   N NE2 . GLN A 1 232 ? 89.414  66.339  139.938 1.00 423.51 ? 231 GLN A NE2 1 
ATOM   562   N N   . ALA A 1 233 ? 88.027  71.241  138.154 1.00 134.90 ? 232 ALA A N   1 
ATOM   563   C CA  . ALA A 1 233 ? 87.746  72.629  138.480 1.00 147.89 ? 232 ALA A CA  1 
ATOM   564   C C   . ALA A 1 233 ? 87.615  73.484  137.214 1.00 99.21  ? 232 ALA A C   1 
ATOM   565   O O   . ALA A 1 233 ? 86.876  74.461  137.230 1.00 102.50 ? 232 ALA A O   1 
ATOM   566   C CB  . ALA A 1 233 ? 88.804  73.149  139.435 1.00 200.50 ? 232 ALA A CB  1 
ATOM   567   N N   . PHE A 1 234 ? 88.298  73.121  136.129 1.00 80.19  ? 233 PHE A N   1 
ATOM   568   C CA  . PHE A 1 234 ? 88.184  73.834  134.863 1.00 91.13  ? 233 PHE A CA  1 
ATOM   569   C C   . PHE A 1 234 ? 86.848  73.585  134.192 1.00 106.02 ? 233 PHE A C   1 
ATOM   570   O O   . PHE A 1 234 ? 86.464  74.391  133.348 1.00 127.91 ? 233 PHE A O   1 
ATOM   571   C CB  . PHE A 1 234 ? 89.326  73.432  133.935 1.00 99.27  ? 233 PHE A CB  1 
ATOM   572   C CG  . PHE A 1 234 ? 89.514  74.204  132.659 1.00 71.55  ? 233 PHE A CG  1 
ATOM   573   C CD1 . PHE A 1 234 ? 89.535  75.568  132.641 1.00 99.42  ? 233 PHE A CD1 1 
ATOM   574   C CD2 . PHE A 1 234 ? 89.708  73.562  131.469 1.00 70.98  ? 233 PHE A CD2 1 
ATOM   575   C CE1 . PHE A 1 234 ? 89.729  76.253  131.454 1.00 124.11 ? 233 PHE A CE1 1 
ATOM   576   C CE2 . PHE A 1 234 ? 89.920  74.250  130.285 1.00 81.68  ? 233 PHE A CE2 1 
ATOM   577   C CZ  . PHE A 1 234 ? 89.931  75.588  130.282 1.00 83.18  ? 233 PHE A CZ  1 
ATOM   578   N N   . GLN A 1 235 ? 86.127  72.516  134.567 1.00 131.38 ? 234 GLN A N   1 
ATOM   579   C CA  . GLN A 1 235 ? 84.943  72.092  133.834 1.00 151.51 ? 234 GLN A CA  1 
ATOM   580   C C   . GLN A 1 235 ? 83.625  72.155  134.632 1.00 203.02 ? 234 GLN A C   1 
ATOM   581   O O   . GLN A 1 235 ? 82.578  72.409  134.050 1.00 200.86 ? 234 GLN A O   1 
ATOM   582   C CB  . GLN A 1 235 ? 85.232  70.661  133.390 1.00 161.85 ? 234 GLN A CB  1 
ATOM   583   C CG  . GLN A 1 235 ? 86.366  70.523  132.374 1.00 126.09 ? 234 GLN A CG  1 
ATOM   584   C CD  . GLN A 1 235 ? 85.851  70.895  131.002 1.00 203.08 ? 234 GLN A CD  1 
ATOM   585   O OE1 . GLN A 1 235 ? 84.852  71.598  130.801 1.00 182.11 ? 234 GLN A OE1 1 
ATOM   586   N NE2 . GLN A 1 235 ? 86.542  70.399  129.987 1.00 320.07 ? 234 GLN A NE2 1 
ATOM   587   N N   . GLY A 1 236 ? 83.645  71.922  135.951 1.00 229.98 ? 235 GLY A N   1 
ATOM   588   C CA  . GLY A 1 236 ? 82.455  71.477  136.672 1.00 218.96 ? 235 GLY A CA  1 
ATOM   589   C C   . GLY A 1 236 ? 82.366  69.948  136.639 1.00 309.15 ? 235 GLY A C   1 
ATOM   590   O O   . GLY A 1 236 ? 82.879  69.301  135.710 1.00 372.00 ? 235 GLY A O   1 
ATOM   591   N N   . HIS A 1 237 ? 81.729  69.363  137.667 1.00 343.68 ? 236 HIS A N   1 
ATOM   592   C CA  . HIS A 1 237 ? 81.853  67.930  137.924 1.00 383.19 ? 236 HIS A CA  1 
ATOM   593   C C   . HIS A 1 237 ? 81.075  67.106  136.898 1.00 330.61 ? 236 HIS A C   1 
ATOM   594   O O   . HIS A 1 237 ? 80.195  67.625  136.204 1.00 238.93 ? 236 HIS A O   1 
ATOM   595   C CB  . HIS A 1 237 ? 81.486  67.622  139.381 1.00 409.56 ? 236 HIS A CB  1 
ATOM   596   C CG  . HIS A 1 237 ? 82.431  68.294  140.325 1.00 453.68 ? 236 HIS A CG  1 
ATOM   597   N ND1 . HIS A 1 237 ? 83.751  67.924  140.484 1.00 439.09 ? 236 HIS A ND1 1 
ATOM   598   C CD2 . HIS A 1 237 ? 82.238  69.328  141.142 1.00 479.93 ? 236 HIS A CD2 1 
ATOM   599   C CE1 . HIS A 1 237 ? 84.325  68.712  141.379 1.00 432.06 ? 236 HIS A CE1 1 
ATOM   600   N NE2 . HIS A 1 237 ? 83.421  69.573  141.793 1.00 472.81 ? 236 HIS A NE2 1 
ATOM   601   N N   . GLY A 1 238 ? 81.437  65.812  136.820 1.00 350.25 ? 237 GLY A N   1 
ATOM   602   C CA  . GLY A 1 238 ? 80.874  64.882  135.852 1.00 381.58 ? 237 GLY A CA  1 
ATOM   603   C C   . GLY A 1 238 ? 81.576  64.986  134.502 1.00 380.75 ? 237 GLY A C   1 
ATOM   604   O O   . GLY A 1 238 ? 82.141  63.998  134.033 1.00 425.90 ? 237 GLY A O   1 
ATOM   605   N N   . ALA A 1 239 ? 81.526  66.188  133.896 1.00 320.49 ? 238 ALA A N   1 
ATOM   606   C CA  . ALA A 1 239 ? 82.328  66.540  132.734 1.00 296.70 ? 238 ALA A CA  1 
ATOM   607   C C   . ALA A 1 239 ? 83.821  66.688  133.065 1.00 310.72 ? 238 ALA A C   1 
ATOM   608   O O   . ALA A 1 239 ? 84.597  66.941  132.137 1.00 312.52 ? 238 ALA A O   1 
ATOM   609   C CB  . ALA A 1 239 ? 81.776  67.802  132.112 1.00 251.05 ? 238 ALA A CB  1 
ATOM   610   N N   . GLY A 1 240 ? 84.234  66.539  134.346 1.00 261.67 ? 239 GLY A N   1 
ATOM   611   C CA  . GLY A 1 240 ? 85.631  66.621  134.736 1.00 239.50 ? 239 GLY A CA  1 
ATOM   612   C C   . GLY A 1 240 ? 86.478  65.415  134.321 1.00 190.21 ? 239 GLY A C   1 
ATOM   613   O O   . GLY A 1 240 ? 86.888  64.668  135.197 1.00 170.82 ? 239 GLY A O   1 
ATOM   614   N N   . ASN A 1 241 ? 86.727  65.265  133.003 1.00 173.26 ? 240 ASN A N   1 
ATOM   615   C CA  . ASN A 1 241 ? 87.537  64.195  132.422 1.00 144.51 ? 240 ASN A CA  1 
ATOM   616   C C   . ASN A 1 241 ? 88.142  64.665  131.097 1.00 143.70 ? 240 ASN A C   1 
ATOM   617   O O   . ASN A 1 241 ? 87.696  65.674  130.541 1.00 176.62 ? 240 ASN A O   1 
ATOM   618   C CB  . ASN A 1 241 ? 86.726  62.907  132.209 1.00 187.63 ? 240 ASN A CB  1 
ATOM   619   C CG  . ASN A 1 241 ? 85.570  63.035  131.240 1.00 218.81 ? 240 ASN A CG  1 
ATOM   620   O OD1 . ASN A 1 241 ? 85.782  63.300  130.056 1.00 209.84 ? 240 ASN A OD1 1 
ATOM   621   N ND2 . ASN A 1 241 ? 84.358  62.849  131.732 1.00 222.79 ? 240 ASN A ND2 1 
ATOM   622   N N   . LEU A 1 242 ? 89.139  63.922  130.578 1.00 116.30 ? 241 LEU A N   1 
ATOM   623   C CA  . LEU A 1 242 ? 89.928  64.334  129.421 1.00 153.46 ? 241 LEU A CA  1 
ATOM   624   C C   . LEU A 1 242 ? 89.072  64.474  128.161 1.00 173.02 ? 241 LEU A C   1 
ATOM   625   O O   . LEU A 1 242 ? 89.354  65.329  127.318 1.00 207.12 ? 241 LEU A O   1 
ATOM   626   C CB  . LEU A 1 242 ? 91.024  63.296  129.195 1.00 151.80 ? 241 LEU A CB  1 
ATOM   627   C CG  . LEU A 1 242 ? 92.086  63.191  130.283 1.00 124.27 ? 241 LEU A CG  1 
ATOM   628   C CD1 . LEU A 1 242 ? 92.823  61.866  130.236 1.00 170.24 ? 241 LEU A CD1 1 
ATOM   629   C CD2 . LEU A 1 242 ? 93.089  64.262  130.100 1.00 140.14 ? 241 LEU A CD2 1 
ATOM   630   N N   . ALA A 1 243 ? 88.030  63.648  128.017 1.00 135.14 ? 242 ALA A N   1 
ATOM   631   C CA  . ALA A 1 243 ? 87.142  63.784  126.873 1.00 189.24 ? 242 ALA A CA  1 
ATOM   632   C C   . ALA A 1 243 ? 86.322  65.077  126.962 1.00 168.93 ? 242 ALA A C   1 
ATOM   633   O O   . ALA A 1 243 ? 85.887  65.619  125.927 1.00 157.57 ? 242 ALA A O   1 
ATOM   634   C CB  . ALA A 1 243 ? 86.254  62.565  126.765 1.00 283.02 ? 242 ALA A CB  1 
ATOM   635   N N   . GLY A 1 244 ? 86.096  65.572  128.190 1.00 178.96 ? 243 GLY A N   1 
ATOM   636   C CA  . GLY A 1 244 ? 85.512  66.884  128.403 1.00 218.71 ? 243 GLY A CA  1 
ATOM   637   C C   . GLY A 1 244 ? 86.432  67.984  127.901 1.00 168.99 ? 243 GLY A C   1 
ATOM   638   O O   . GLY A 1 244 ? 85.975  68.932  127.237 1.00 172.21 ? 243 GLY A O   1 
ATOM   639   N N   . LEU A 1 245 ? 87.719  67.853  128.252 1.00 143.52 ? 244 LEU A N   1 
ATOM   640   C CA  . LEU A 1 245 ? 88.713  68.835  127.872 1.00 165.20 ? 244 LEU A CA  1 
ATOM   641   C C   . LEU A 1 245 ? 88.798  68.883  126.349 1.00 137.67 ? 244 LEU A C   1 
ATOM   642   O O   . LEU A 1 245 ? 88.975  69.959  125.802 1.00 155.67 ? 244 LEU A O   1 
ATOM   643   C CB  . LEU A 1 245 ? 90.051  68.553  128.585 1.00 116.09 ? 244 LEU A CB  1 
ATOM   644   C CG  . LEU A 1 245 ? 91.230  69.386  128.095 1.00 136.76 ? 244 LEU A CG  1 
ATOM   645   C CD1 . LEU A 1 245 ? 91.025  70.900  128.184 1.00 145.59 ? 244 LEU A CD1 1 
ATOM   646   C CD2 . LEU A 1 245 ? 92.446  69.047  128.880 1.00 154.10 ? 244 LEU A CD2 1 
ATOM   647   N N   . LYS A 1 246 ? 88.701  67.752  125.666 1.00 132.44 ? 245 LYS A N   1 
ATOM   648   C CA  . LYS A 1 246 ? 88.747  67.730  124.211 1.00 181.57 ? 245 LYS A CA  1 
ATOM   649   C C   . LYS A 1 246 ? 87.714  68.686  123.625 1.00 154.09 ? 245 LYS A C   1 
ATOM   650   O O   . LYS A 1 246 ? 87.907  69.164  122.499 1.00 179.95 ? 245 LYS A O   1 
ATOM   651   C CB  . LYS A 1 246 ? 88.553  66.286  123.735 1.00 227.42 ? 245 LYS A CB  1 
ATOM   652   C CG  . LYS A 1 246 ? 88.667  66.014  122.239 1.00 234.77 ? 245 LYS A CG  1 
ATOM   653   C CD  . LYS A 1 246 ? 88.648  64.520  121.925 1.00 280.62 ? 245 LYS A CD  1 
ATOM   654   C CE  . LYS A 1 246 ? 87.318  63.902  122.316 1.00 298.14 ? 245 LYS A CE  1 
ATOM   655   N NZ  . LYS A 1 246 ? 87.048  62.609  121.651 1.00 331.44 ? 245 LYS A NZ  1 
ATOM   656   N N   . GLY A 1 247 ? 86.620  68.949  124.365 1.00 138.80 ? 246 GLY A N   1 
ATOM   657   C CA  . GLY A 1 247 ? 85.586  69.885  123.925 1.00 221.74 ? 246 GLY A CA  1 
ATOM   658   C C   . GLY A 1 247 ? 85.998  71.355  123.935 1.00 180.25 ? 246 GLY A C   1 
ATOM   659   O O   . GLY A 1 247 ? 85.480  72.152  123.144 1.00 184.72 ? 246 GLY A O   1 
ATOM   660   N N   . ARG A 1 248 ? 86.916  71.712  124.845 1.00 153.01 ? 247 ARG A N   1 
ATOM   661   C CA  . ARG A 1 248 ? 87.178  73.102  125.176 1.00 147.16 ? 247 ARG A CA  1 
ATOM   662   C C   . ARG A 1 248 ? 88.237  73.765  124.327 1.00 134.30 ? 247 ARG A C   1 
ATOM   663   O O   . ARG A 1 248 ? 88.282  74.985  124.344 1.00 131.20 ? 247 ARG A O   1 
ATOM   664   C CB  . ARG A 1 248 ? 87.704  73.208  126.593 1.00 127.60 ? 247 ARG A CB  1 
ATOM   665   C CG  . ARG A 1 248 ? 86.576  72.924  127.555 1.00 136.19 ? 247 ARG A CG  1 
ATOM   666   C CD  . ARG A 1 248 ? 85.478  73.988  127.637 1.00 132.66 ? 247 ARG A CD  1 
ATOM   667   N NE  . ARG A 1 248 ? 84.728  73.654  128.841 1.00 159.93 ? 247 ARG A NE  1 
ATOM   668   C CZ  . ARG A 1 248 ? 83.594  74.223  129.188 1.00 167.06 ? 247 ARG A CZ  1 
ATOM   669   N NH1 . ARG A 1 248 ? 82.940  73.742  130.234 1.00 161.65 ? 247 ARG A NH1 1 
ATOM   670   N NH2 . ARG A 1 248 ? 83.142  75.250  128.477 1.00 141.98 ? 247 ARG A NH2 1 
ATOM   671   N N   . LEU A 1 249 ? 89.040  72.989  123.606 1.00 109.46 ? 248 LEU A N   1 
ATOM   672   C CA  . LEU A 1 249 ? 90.152  73.549  122.875 1.00 106.18 ? 248 LEU A CA  1 
ATOM   673   C C   . LEU A 1 249 ? 89.751  74.681  121.896 1.00 133.18 ? 248 LEU A C   1 
ATOM   674   O O   . LEU A 1 249 ? 90.632  75.413  121.459 1.00 129.25 ? 248 LEU A O   1 
ATOM   675   C CB  . LEU A 1 249 ? 90.841  72.434  122.093 1.00 105.10 ? 248 LEU A CB  1 
ATOM   676   C CG  . LEU A 1 249 ? 91.298  71.169  122.811 1.00 119.46 ? 248 LEU A CG  1 
ATOM   677   C CD1 . LEU A 1 249 ? 91.991  70.285  121.801 1.00 187.91 ? 248 LEU A CD1 1 
ATOM   678   C CD2 . LEU A 1 249 ? 92.248  71.425  123.930 1.00 133.10 ? 248 LEU A CD2 1 
ATOM   679   N N   . ASP A 1 250 ? 88.477  74.876  121.507 1.00 128.32 ? 249 ASP A N   1 
ATOM   680   C CA  . ASP A 1 250 ? 88.149  76.001  120.636 1.00 167.72 ? 249 ASP A CA  1 
ATOM   681   C C   . ASP A 1 250 ? 88.253  77.329  121.395 1.00 156.06 ? 249 ASP A C   1 
ATOM   682   O O   . ASP A 1 250 ? 88.498  78.399  120.823 1.00 204.96 ? 249 ASP A O   1 
ATOM   683   C CB  . ASP A 1 250 ? 86.769  75.811  119.985 1.00 262.95 ? 249 ASP A CB  1 
ATOM   684   C CG  . ASP A 1 250 ? 86.612  76.579  118.679 1.00 367.20 ? 249 ASP A CG  1 
ATOM   685   O OD1 . ASP A 1 250 ? 87.599  76.640  117.904 1.00 394.39 ? 249 ASP A OD1 1 
ATOM   686   O OD2 . ASP A 1 250 ? 85.506  77.107  118.439 1.00 437.32 ? 249 ASP A OD2 1 
ATOM   687   N N   . TYR A 1 251 ? 88.028  77.279  122.710 1.00 142.76 ? 250 TYR A N   1 
ATOM   688   C CA  . TYR A 1 251 ? 88.300  78.417  123.571 1.00 142.46 ? 250 TYR A CA  1 
ATOM   689   C C   . TYR A 1 251 ? 89.775  78.712  123.618 1.00 105.51 ? 250 TYR A C   1 
ATOM   690   O O   . TYR A 1 251 ? 90.174  79.844  123.378 1.00 112.73 ? 250 TYR A O   1 
ATOM   691   C CB  . TYR A 1 251 ? 87.906  78.100  124.989 1.00 128.86 ? 250 TYR A CB  1 
ATOM   692   C CG  . TYR A 1 251 ? 88.224  79.175  126.010 1.00 116.36 ? 250 TYR A CG  1 
ATOM   693   C CD1 . TYR A 1 251 ? 87.934  80.531  125.848 1.00 151.36 ? 250 TYR A CD1 1 
ATOM   694   C CD2 . TYR A 1 251 ? 88.786  78.786  127.193 1.00 113.30 ? 250 TYR A CD2 1 
ATOM   695   C CE1 . TYR A 1 251 ? 88.223  81.448  126.846 1.00 122.39 ? 250 TYR A CE1 1 
ATOM   696   C CE2 . TYR A 1 251 ? 89.052  79.681  128.196 1.00 107.06 ? 250 TYR A CE2 1 
ATOM   697   C CZ  . TYR A 1 251 ? 88.771  81.010  128.027 1.00 99.64  ? 250 TYR A CZ  1 
ATOM   698   O OH  . TYR A 1 251 ? 89.082  81.805  129.077 1.00 116.35 ? 250 TYR A OH  1 
ATOM   699   N N   . LEU A 1 252 ? 90.547  77.677  123.907 1.00 79.48  ? 251 LEU A N   1 
ATOM   700   C CA  . LEU A 1 252 ? 91.978  77.833  123.977 1.00 81.25  ? 251 LEU A CA  1 
ATOM   701   C C   . LEU A 1 252 ? 92.507  78.348  122.634 1.00 95.30  ? 251 LEU A C   1 
ATOM   702   O O   . LEU A 1 252 ? 93.368  79.238  122.624 1.00 138.90 ? 251 LEU A O   1 
ATOM   703   C CB  . LEU A 1 252 ? 92.635  76.525  124.424 1.00 72.24  ? 251 LEU A CB  1 
ATOM   704   C CG  . LEU A 1 252 ? 92.253  75.951  125.813 1.00 101.26 ? 251 LEU A CG  1 
ATOM   705   C CD1 . LEU A 1 252 ? 93.414  75.106  126.264 1.00 109.66 ? 251 LEU A CD1 1 
ATOM   706   C CD2 . LEU A 1 252 ? 91.938  76.952  126.933 1.00 105.72 ? 251 LEU A CD2 1 
ATOM   707   N N   . SER A 1 253 ? 92.001  77.835  121.516 1.00 76.62  ? 252 SER A N   1 
ATOM   708   C CA  . SER A 1 253 ? 92.429  78.334  120.237 1.00 106.65 ? 252 SER A CA  1 
ATOM   709   C C   . SER A 1 253 ? 92.082  79.828  120.110 1.00 102.44 ? 252 SER A C   1 
ATOM   710   O O   . SER A 1 253 ? 92.864  80.570  119.475 1.00 191.55 ? 252 SER A O   1 
ATOM   711   C CB  . SER A 1 253 ? 91.856  77.448  119.166 1.00 173.24 ? 252 SER A CB  1 
ATOM   712   O OG  . SER A 1 253 ? 92.285  77.857  117.877 1.00 262.02 ? 252 SER A OG  1 
ATOM   713   N N   . SER A 1 254 ? 90.957  80.283  120.705 1.00 74.74  ? 253 SER A N   1 
ATOM   714   C CA  . SER A 1 254 ? 90.583  81.711  120.793 1.00 133.89 ? 253 SER A CA  1 
ATOM   715   C C   . SER A 1 254 ? 91.565  82.568  121.585 1.00 132.54 ? 253 SER A C   1 
ATOM   716   O O   . SER A 1 254 ? 91.873  83.695  121.174 1.00 173.23 ? 253 SER A O   1 
ATOM   717   C CB  . SER A 1 254 ? 89.182  81.920  121.319 1.00 133.83 ? 253 SER A CB  1 
ATOM   718   O OG  . SER A 1 254 ? 88.273  81.222  120.470 1.00 279.73 ? 253 SER A OG  1 
ATOM   719   N N   . LEU A 1 255 ? 92.073  82.013  122.680 1.00 107.83 ? 254 LEU A N   1 
ATOM   720   C CA  . LEU A 1 255 ? 93.171  82.623  123.429 1.00 68.19  ? 254 LEU A CA  1 
ATOM   721   C C   . LEU A 1 255 ? 94.505  82.615  122.706 1.00 69.69  ? 254 LEU A C   1 
ATOM   722   O O   . LEU A 1 255 ? 95.422  83.263  123.174 1.00 97.95  ? 254 LEU A O   1 
ATOM   723   C CB  . LEU A 1 255 ? 93.363  81.827  124.719 1.00 55.10  ? 254 LEU A CB  1 
ATOM   724   C CG  . LEU A 1 255 ? 92.178  81.869  125.682 1.00 64.04  ? 254 LEU A CG  1 
ATOM   725   C CD1 . LEU A 1 255 ? 92.525  81.221  126.986 1.00 74.55  ? 254 LEU A CD1 1 
ATOM   726   C CD2 . LEU A 1 255 ? 91.715  83.280  125.933 1.00 56.17  ? 254 LEU A CD2 1 
ATOM   727   N N   . LYS A 1 256 ? 94.643  81.868  121.623 1.00 93.50  ? 255 LYS A N   1 
ATOM   728   C CA  . LYS A 1 256 ? 95.862  81.808  120.824 1.00 114.31 ? 255 LYS A CA  1 
ATOM   729   C C   . LYS A 1 256 ? 97.022  81.219  121.647 1.00 75.73  ? 255 LYS A C   1 
ATOM   730   O O   . LYS A 1 256 ? 98.192  81.469  121.363 1.00 80.20  ? 255 LYS A O   1 
ATOM   731   C CB  . LYS A 1 256 ? 96.112  83.178  120.157 1.00 118.12 ? 255 LYS A CB  1 
ATOM   732   C CG  . LYS A 1 256 ? 94.989  83.661  119.243 1.00 112.26 ? 255 LYS A CG  1 
ATOM   733   C CD  . LYS A 1 256 ? 95.386  84.861  118.375 1.00 212.45 ? 255 LYS A CD  1 
ATOM   734   C CE  . LYS A 1 256 ? 94.217  85.404  117.582 1.00 331.48 ? 255 LYS A CE  1 
ATOM   735   N NZ  . LYS A 1 256 ? 93.059  85.768  118.444 1.00 360.92 ? 255 LYS A NZ  1 
ATOM   736   N N   . VAL A 1 257 ? 96.675  80.404  122.661 1.00 66.60  ? 256 VAL A N   1 
ATOM   737   C CA  . VAL A 1 257 ? 97.689  79.803  123.527 1.00 72.85  ? 256 VAL A CA  1 
ATOM   738   C C   . VAL A 1 257 ? 98.386  78.625  122.865 1.00 66.52  ? 256 VAL A C   1 
ATOM   739   O O   . VAL A 1 257 ? 97.736  77.645  122.621 1.00 80.51  ? 256 VAL A O   1 
ATOM   740   C CB  . VAL A 1 257 ? 97.184  79.349  124.887 1.00 65.69  ? 256 VAL A CB  1 
ATOM   741   C CG1 . VAL A 1 257 ? 96.926  80.586  125.706 1.00 114.78 ? 256 VAL A CG1 1 
ATOM   742   C CG2 . VAL A 1 257 ? 95.994  78.475  124.850 1.00 66.73  ? 256 VAL A CG2 1 
ATOM   743   N N   . LYS A 1 258 ? 99.702  78.769  122.585 1.00 70.28  ? 257 LYS A N   1 
ATOM   744   C CA  . LYS A 1 258 ? 100.536 77.842  121.836 1.00 73.75  ? 257 LYS A CA  1 
ATOM   745   C C   . LYS A 1 258 ? 100.883 76.643  122.697 1.00 53.50  ? 257 LYS A C   1 
ATOM   746   O O   . LYS A 1 258 ? 101.942 76.074  122.502 1.00 127.81 ? 257 LYS A O   1 
ATOM   747   C CB  . LYS A 1 258 ? 101.772 78.614  121.293 1.00 80.36  ? 257 LYS A CB  1 
ATOM   748   C CG  . LYS A 1 258 ? 101.428 79.734  120.308 1.00 108.06 ? 257 LYS A CG  1 
ATOM   749   C CD  . LYS A 1 258 ? 100.766 79.350  119.009 1.00 167.36 ? 257 LYS A CD  1 
ATOM   750   C CE  . LYS A 1 258 ? 100.593 80.528  118.075 1.00 188.25 ? 257 LYS A CE  1 
ATOM   751   N NZ  . LYS A 1 258 ? 100.200 80.117  116.709 1.00 265.84 ? 257 LYS A NZ  1 
ATOM   752   N N   . GLY A 1 259 ? 100.057 76.282  123.641 1.00 53.45  ? 258 GLY A N   1 
ATOM   753   C CA  . GLY A 1 259 ? 100.507 75.467  124.775 1.00 64.10  ? 258 GLY A CA  1 
ATOM   754   C C   . GLY A 1 259 ? 99.394  75.225  125.802 1.00 64.34  ? 258 GLY A C   1 
ATOM   755   O O   . GLY A 1 259 ? 98.346  75.860  125.783 1.00 67.19  ? 258 GLY A O   1 
ATOM   756   N N   . LEU A 1 260 ? 99.625  74.217  126.616 1.00 57.20  ? 259 LEU A N   1 
ATOM   757   C CA  . LEU A 1 260 ? 98.721  73.654  127.606 1.00 57.35  ? 259 LEU A CA  1 
ATOM   758   C C   . LEU A 1 260 ? 99.611  72.869  128.565 1.00 76.57  ? 259 LEU A C   1 
ATOM   759   O O   . LEU A 1 260 ? 100.668 72.377  128.134 1.00 120.05 ? 259 LEU A O   1 
ATOM   760   C CB  . LEU A 1 260 ? 97.759  72.607  127.059 1.00 58.09  ? 259 LEU A CB  1 
ATOM   761   C CG  . LEU A 1 260 ? 96.317  72.945  126.981 1.00 78.83  ? 259 LEU A CG  1 
ATOM   762   C CD1 . LEU A 1 260 ? 95.510  71.787  126.478 1.00 117.36 ? 259 LEU A CD1 1 
ATOM   763   C CD2 . LEU A 1 260 ? 95.854  73.144  128.357 1.00 141.80 ? 259 LEU A CD2 1 
ATOM   764   N N   . VAL A 1 261 ? 99.169  72.711  129.803 1.00 60.19  ? 260 VAL A N   1 
ATOM   765   C CA  . VAL A 1 261 ? 99.914  71.948  130.776 1.00 49.12  ? 260 VAL A CA  1 
ATOM   766   C C   . VAL A 1 261 ? 98.885  71.222  131.625 1.00 60.02  ? 260 VAL A C   1 
ATOM   767   O O   . VAL A 1 261 ? 98.229  71.885  132.441 1.00 81.05  ? 260 VAL A O   1 
ATOM   768   C CB  . VAL A 1 261 ? 100.763 72.911  131.607 1.00 53.62  ? 260 VAL A CB  1 
ATOM   769   C CG1 . VAL A 1 261 ? 101.502 72.206  132.741 1.00 79.40  ? 260 VAL A CG1 1 
ATOM   770   C CG2 . VAL A 1 261 ? 101.764 73.675  130.749 1.00 54.15  ? 260 VAL A CG2 1 
ATOM   771   N N   . LEU A 1 262 ? 98.718  69.899  131.463 1.00 66.58  ? 261 LEU A N   1 
ATOM   772   C CA  . LEU A 1 262 ? 97.662  69.190  132.221 1.00 74.69  ? 261 LEU A CA  1 
ATOM   773   C C   . LEU A 1 262 ? 98.281  68.755  133.519 1.00 79.95  ? 261 LEU A C   1 
ATOM   774   O O   . LEU A 1 262 ? 99.184  67.923  133.520 1.00 81.74  ? 261 LEU A O   1 
ATOM   775   C CB  . LEU A 1 262 ? 97.013  67.944  131.648 1.00 57.92  ? 261 LEU A CB  1 
ATOM   776   C CG  . LEU A 1 262 ? 96.014  68.197  130.558 1.00 93.10  ? 261 LEU A CG  1 
ATOM   777   C CD1 . LEU A 1 262 ? 96.375  69.325  129.504 1.00 87.27  ? 261 LEU A CD1 1 
ATOM   778   C CD2 . LEU A 1 262 ? 95.839  66.875  129.817 1.00 135.85 ? 261 LEU A CD2 1 
ATOM   779   N N   . GLY A 1 263 ? 97.786  69.415  134.586 1.00 157.56 ? 262 GLY A N   1 
ATOM   780   C CA  . GLY A 1 263 ? 98.179  69.112  135.932 1.00 152.90 ? 262 GLY A CA  1 
ATOM   781   C C   . GLY A 1 263 ? 97.977  67.620  136.120 1.00 115.15 ? 262 GLY A C   1 
ATOM   782   O O   . GLY A 1 263 ? 97.104  66.998  135.514 1.00 72.38  ? 262 GLY A O   1 
ATOM   783   N N   . PRO A 1 264 ? 98.767  67.029  137.027 1.00 107.43 ? 263 PRO A N   1 
ATOM   784   C CA  . PRO A 1 264 ? 99.035  65.610  136.979 1.00 113.29 ? 263 PRO A CA  1 
ATOM   785   C C   . PRO A 1 264 ? 97.792  64.736  136.932 1.00 127.90 ? 263 PRO A C   1 
ATOM   786   O O   . PRO A 1 264 ? 96.835  64.921  137.692 1.00 123.44 ? 263 PRO A O   1 
ATOM   787   C CB  . PRO A 1 264 ? 99.753  65.410  138.295 1.00 119.95 ? 263 PRO A CB  1 
ATOM   788   C CG  . PRO A 1 264 ? 100.452 66.676  138.526 1.00 122.99 ? 263 PRO A CG  1 
ATOM   789   C CD  . PRO A 1 264 ? 99.436  67.706  138.132 1.00 119.55 ? 263 PRO A CD  1 
ATOM   790   N N   . ILE A 1 265 ? 97.872  63.765  136.023 1.00 116.88 ? 264 ILE A N   1 
ATOM   791   C CA  . ILE A 1 265 ? 96.800  62.837  135.783 1.00 95.36  ? 264 ILE A CA  1 
ATOM   792   C C   . ILE A 1 265 ? 97.244  61.442  136.110 1.00 94.30  ? 264 ILE A C   1 
ATOM   793   O O   . ILE A 1 265 ? 96.440  60.523  135.916 1.00 123.85 ? 264 ILE A O   1 
ATOM   794   C CB  . ILE A 1 265 ? 96.330  62.910  134.312 1.00 103.12 ? 264 ILE A CB  1 
ATOM   795   C CG1 . ILE A 1 265 ? 97.439  62.631  133.298 1.00 115.62 ? 264 ILE A CG1 1 
ATOM   796   C CG2 . ILE A 1 265 ? 95.623  64.234  134.025 1.00 108.70 ? 264 ILE A CG2 1 
ATOM   797   C CD1 . ILE A 1 265 ? 96.914  62.397  131.917 1.00 171.11 ? 264 ILE A CD1 1 
ATOM   798   N N   . HIS A 1 266 ? 98.475  61.257  136.592 1.00 87.21  ? 265 HIS A N   1 
ATOM   799   C CA  . HIS A 1 266 ? 98.917  59.899  136.833 1.00 116.75 ? 265 HIS A CA  1 
ATOM   800   C C   . HIS A 1 266 ? 98.313  59.354  138.130 1.00 113.46 ? 265 HIS A C   1 
ATOM   801   O O   . HIS A 1 266 ? 97.846  60.134  138.949 1.00 109.86 ? 265 HIS A O   1 
ATOM   802   C CB  . HIS A 1 266 ? 100.422 59.906  136.767 1.00 142.07 ? 265 HIS A CB  1 
ATOM   803   C CG  . HIS A 1 266 ? 101.016 60.750  137.817 1.00 110.79 ? 265 HIS A CG  1 
ATOM   804   N ND1 . HIS A 1 266 ? 101.518 61.995  137.544 1.00 148.91 ? 265 HIS A ND1 1 
ATOM   805   C CD2 . HIS A 1 266 ? 101.223 60.514  139.094 1.00 93.20  ? 265 HIS A CD2 1 
ATOM   806   C CE1 . HIS A 1 266 ? 102.005 62.485  138.663 1.00 188.27 ? 265 HIS A CE1 1 
ATOM   807   N NE2 . HIS A 1 266 ? 101.838 61.600  139.609 1.00 134.54 ? 265 HIS A NE2 1 
ATOM   808   N N   . LYS A 1 267 ? 98.310  58.011  138.279 1.00 118.00 ? 266 LYS A N   1 
ATOM   809   C CA  . LYS A 1 267 ? 97.689  57.345  139.419 1.00 146.50 ? 266 LYS A CA  1 
ATOM   810   C C   . LYS A 1 267 ? 98.549  57.514  140.673 1.00 144.66 ? 266 LYS A C   1 
ATOM   811   O O   . LYS A 1 267 ? 99.437  56.707  140.965 1.00 175.60 ? 266 LYS A O   1 
ATOM   812   C CB  . LYS A 1 267 ? 97.432  55.873  139.079 1.00 220.51 ? 266 LYS A CB  1 
ATOM   813   C CG  . LYS A 1 267 ? 96.711  55.074  140.161 1.00 252.34 ? 266 LYS A CG  1 
ATOM   814   C CD  . LYS A 1 267 ? 96.459  53.613  139.777 1.00 278.39 ? 266 LYS A CD  1 
ATOM   815   C CE  . LYS A 1 267 ? 96.212  52.683  140.955 1.00 308.71 ? 266 LYS A CE  1 
ATOM   816   N NZ  . LYS A 1 267 ? 97.432  52.400  141.769 1.00 349.81 ? 266 LYS A NZ  1 
ATOM   817   N N   . ASN A 1 268 ? 98.255  58.571  141.429 1.00 149.80 ? 267 ASN A N   1 
ATOM   818   C CA  . ASN A 1 268 ? 98.903  58.867  142.695 1.00 146.41 ? 267 ASN A CA  1 
ATOM   819   C C   . ASN A 1 268 ? 97.940  58.524  143.822 1.00 160.42 ? 267 ASN A C   1 
ATOM   820   O O   . ASN A 1 268 ? 96.782  58.949  143.796 1.00 146.45 ? 267 ASN A O   1 
ATOM   821   C CB  . ASN A 1 268 ? 99.317  60.344  142.745 1.00 216.99 ? 267 ASN A CB  1 
ATOM   822   C CG  . ASN A 1 268 ? 99.740  60.853  144.106 1.00 170.66 ? 267 ASN A CG  1 
ATOM   823   O OD1 . ASN A 1 268 ? 99.318  61.926  144.510 1.00 129.16 ? 267 ASN A OD1 1 
ATOM   824   N ND2 . ASN A 1 268 ? 100.570 60.115  144.816 1.00 160.25 ? 267 ASN A ND2 1 
ATOM   825   N N   . GLN A 1 269 ? 98.447  57.756  144.801 1.00 170.10 ? 268 GLN A N   1 
ATOM   826   C CA  . GLN A 1 269 ? 97.780  57.557  146.080 1.00 219.52 ? 268 GLN A CA  1 
ATOM   827   C C   . GLN A 1 269 ? 98.518  58.383  147.136 1.00 205.30 ? 268 GLN A C   1 
ATOM   828   O O   . GLN A 1 269 ? 99.740  58.314  147.236 1.00 158.55 ? 268 GLN A O   1 
ATOM   829   C CB  . GLN A 1 269 ? 97.712  56.050  146.378 1.00 259.05 ? 268 GLN A CB  1 
ATOM   830   C CG  . GLN A 1 269 ? 97.361  55.663  147.815 1.00 292.79 ? 268 GLN A CG  1 
ATOM   831   C CD  . GLN A 1 269 ? 96.041  56.191  148.335 1.00 344.51 ? 268 GLN A CD  1 
ATOM   832   O OE1 . GLN A 1 269 ? 95.410  57.077  147.760 1.00 332.32 ? 268 GLN A OE1 1 
ATOM   833   N NE2 . GLN A 1 269 ? 95.605  55.642  149.460 1.00 382.56 ? 268 GLN A NE2 1 
ATOM   834   N N   . LYS A 1 270 ? 97.768  59.152  147.937 1.00 196.92 ? 269 LYS A N   1 
ATOM   835   C CA  . LYS A 1 270 ? 98.348  60.195  148.785 1.00 179.04 ? 269 LYS A CA  1 
ATOM   836   C C   . LYS A 1 270 ? 99.459  59.647  149.695 1.00 134.43 ? 269 LYS A C   1 
ATOM   837   O O   . LYS A 1 270 ? 99.217  58.734  150.480 1.00 161.08 ? 269 LYS A O   1 
ATOM   838   C CB  . LYS A 1 270 ? 97.222  60.837  149.602 1.00 164.89 ? 269 LYS A CB  1 
ATOM   839   C CG  . LYS A 1 270 ? 97.665  61.952  150.531 1.00 222.98 ? 269 LYS A CG  1 
ATOM   840   C CD  . LYS A 1 270 ? 96.510  62.607  151.256 1.00 297.17 ? 269 LYS A CD  1 
ATOM   841   C CE  . LYS A 1 270 ? 96.961  63.733  152.163 1.00 367.72 ? 269 LYS A CE  1 
ATOM   842   N NZ  . LYS A 1 270 ? 97.876  63.266  153.234 1.00 395.25 ? 269 LYS A NZ  1 
ATOM   843   N N   . ASP A 1 271 ? 100.671 60.206  149.558 1.00 140.34 ? 270 ASP A N   1 
ATOM   844   C CA  . ASP A 1 271 ? 101.861 59.915  150.362 1.00 192.93 ? 270 ASP A CA  1 
ATOM   845   C C   . ASP A 1 271 ? 102.312 58.445  150.301 1.00 215.89 ? 270 ASP A C   1 
ATOM   846   O O   . ASP A 1 271 ? 103.202 58.074  151.076 1.00 216.52 ? 270 ASP A O   1 
ATOM   847   C CB  . ASP A 1 271 ? 101.677 60.425  151.803 1.00 225.88 ? 270 ASP A CB  1 
ATOM   848   C CG  . ASP A 1 271 ? 101.317 61.899  151.904 1.00 237.84 ? 270 ASP A CG  1 
ATOM   849   O OD1 . ASP A 1 271 ? 101.968 62.698  151.196 1.00 286.47 ? 270 ASP A OD1 1 
ATOM   850   O OD2 . ASP A 1 271 ? 100.399 62.238  152.690 1.00 227.96 ? 270 ASP A OD2 1 
ATOM   851   N N   . ASP A 1 272 ? 101.745 57.622  149.390 1.00 176.25 ? 271 ASP A N   1 
ATOM   852   C CA  . ASP A 1 272 ? 102.145 56.228  149.235 1.00 218.14 ? 271 ASP A CA  1 
ATOM   853   C C   . ASP A 1 272 ? 103.072 56.104  148.018 1.00 195.15 ? 271 ASP A C   1 
ATOM   854   O O   . ASP A 1 272 ? 102.633 56.174  146.862 1.00 258.69 ? 271 ASP A O   1 
ATOM   855   C CB  . ASP A 1 272 ? 100.926 55.303  149.130 1.00 275.25 ? 271 ASP A CB  1 
ATOM   856   C CG  . ASP A 1 272 ? 101.248 53.812  149.184 1.00 335.74 ? 271 ASP A CG  1 
ATOM   857   O OD1 . ASP A 1 272 ? 102.311 53.394  148.644 1.00 344.98 ? 271 ASP A OD1 1 
ATOM   858   O OD2 . ASP A 1 272 ? 100.426 53.067  149.755 1.00 357.55 ? 271 ASP A OD2 1 
ATOM   859   N N   . VAL A 1 273 ? 104.364 55.883  148.293 1.00 156.20 ? 272 VAL A N   1 
ATOM   860   C CA  . VAL A 1 273 ? 105.403 55.834  147.276 1.00 156.71 ? 272 VAL A CA  1 
ATOM   861   C C   . VAL A 1 273 ? 105.199 54.621  146.362 1.00 171.00 ? 272 VAL A C   1 
ATOM   862   O O   . VAL A 1 273 ? 105.515 54.688  145.182 1.00 142.93 ? 272 VAL A O   1 
ATOM   863   C CB  . VAL A 1 273 ? 106.803 55.780  147.918 1.00 215.20 ? 272 VAL A CB  1 
ATOM   864   C CG1 . VAL A 1 273 ? 107.918 55.888  146.875 1.00 225.37 ? 272 VAL A CG1 1 
ATOM   865   C CG2 . VAL A 1 273 ? 106.994 56.807  149.038 1.00 230.32 ? 272 VAL A CG2 1 
ATOM   866   N N   . ALA A 1 274 ? 104.685 53.513  146.921 1.00 200.72 ? 273 ALA A N   1 
ATOM   867   C CA  . ALA A 1 274 ? 104.621 52.230  146.239 1.00 227.37 ? 273 ALA A CA  1 
ATOM   868   C C   . ALA A 1 274 ? 103.349 52.084  145.392 1.00 208.14 ? 273 ALA A C   1 
ATOM   869   O O   . ALA A 1 274 ? 103.415 51.534  144.289 1.00 176.92 ? 273 ALA A O   1 
ATOM   870   C CB  . ALA A 1 274 ? 104.729 51.136  147.280 1.00 289.54 ? 273 ALA A CB  1 
ATOM   871   N N   . GLN A 1 275 ? 102.203 52.558  145.906 1.00 204.10 ? 274 GLN A N   1 
ATOM   872   C CA  . GLN A 1 275 ? 100.937 52.528  145.177 1.00 250.21 ? 274 GLN A CA  1 
ATOM   873   C C   . GLN A 1 275 ? 100.866 53.612  144.092 1.00 246.92 ? 274 GLN A C   1 
ATOM   874   O O   . GLN A 1 275 ? 100.016 53.512  143.200 1.00 260.46 ? 274 GLN A O   1 
ATOM   875   C CB  . GLN A 1 275 ? 99.758  52.705  146.142 1.00 304.17 ? 274 GLN A CB  1 
ATOM   876   C CG  . GLN A 1 275 ? 99.519  51.510  147.057 1.00 327.16 ? 274 GLN A CG  1 
ATOM   877   C CD  . GLN A 1 275 ? 98.938  50.298  146.357 1.00 344.99 ? 274 GLN A CD  1 
ATOM   878   O OE1 . GLN A 1 275 ? 98.661  50.305  145.157 1.00 309.26 ? 274 GLN A OE1 1 
ATOM   879   N NE2 . GLN A 1 275 ? 98.751  49.229  147.115 1.00 396.07 ? 274 GLN A NE2 1 
ATOM   880   N N   . THR A 1 276 ? 101.731 54.641  144.159 1.00 206.64 ? 275 THR A N   1 
ATOM   881   C CA  . THR A 1 276 ? 101.811 55.671  143.132 1.00 177.50 ? 275 THR A CA  1 
ATOM   882   C C   . THR A 1 276 ? 102.605 55.201  141.909 1.00 189.62 ? 275 THR A C   1 
ATOM   883   O O   . THR A 1 276 ? 103.696 54.639  142.029 1.00 186.68 ? 275 THR A O   1 
ATOM   884   C CB  . THR A 1 276 ? 102.478 56.945  143.654 1.00 203.13 ? 275 THR A CB  1 
ATOM   885   O OG1 . THR A 1 276 ? 101.608 57.479  144.646 1.00 244.35 ? 275 THR A OG1 1 
ATOM   886   C CG2 . THR A 1 276 ? 102.728 57.999  142.595 1.00 187.24 ? 275 THR A CG2 1 
ATOM   887   N N   . ASP A 1 277 ? 102.037 55.474  140.721 1.00 207.93 ? 276 ASP A N   1 
ATOM   888   C CA  . ASP A 1 277 ? 102.661 55.236  139.427 1.00 183.36 ? 276 ASP A CA  1 
ATOM   889   C C   . ASP A 1 277 ? 102.566 56.496  138.573 1.00 136.77 ? 276 ASP A C   1 
ATOM   890   O O   . ASP A 1 277 ? 101.531 57.184  138.646 1.00 152.74 ? 276 ASP A O   1 
ATOM   891   C CB  . ASP A 1 277 ? 101.979 54.068  138.720 1.00 201.84 ? 276 ASP A CB  1 
ATOM   892   C CG  . ASP A 1 277 ? 102.559 53.759  137.356 1.00 226.20 ? 276 ASP A CG  1 
ATOM   893   O OD1 . ASP A 1 277 ? 103.726 54.168  137.095 1.00 203.42 ? 276 ASP A OD1 1 
ATOM   894   O OD2 . ASP A 1 277 ? 101.838 53.131  136.546 1.00 287.85 ? 276 ASP A OD2 1 
ATOM   895   N N   . LEU A 1 278 ? 103.638 56.796  137.803 1.00 112.67 ? 277 LEU A N   1 
ATOM   896   C CA  . LEU A 1 278 ? 103.623 57.988  136.947 1.00 157.33 ? 277 LEU A CA  1 
ATOM   897   C C   . LEU A 1 278 ? 103.221 57.623  135.527 1.00 156.13 ? 277 LEU A C   1 
ATOM   898   O O   . LEU A 1 278 ? 103.176 58.528  134.692 1.00 134.99 ? 277 LEU A O   1 
ATOM   899   C CB  . LEU A 1 278 ? 104.966 58.733  136.892 1.00 117.87 ? 277 LEU A CB  1 
ATOM   900   C CG  . LEU A 1 278 ? 105.600 59.049  138.234 1.00 169.18 ? 277 LEU A CG  1 
ATOM   901   C CD1 . LEU A 1 278 ? 106.886 59.833  138.034 1.00 195.46 ? 277 LEU A CD1 1 
ATOM   902   C CD2 . LEU A 1 278 ? 104.613 59.811  139.116 1.00 158.15 ? 277 LEU A CD2 1 
ATOM   903   N N   . LEU A 1 279 ? 102.931 56.341  135.269 1.00 124.61 ? 278 LEU A N   1 
ATOM   904   C CA  . LEU A 1 279 ? 102.724 55.885  133.911 1.00 160.56 ? 278 LEU A CA  1 
ATOM   905   C C   . LEU A 1 279 ? 101.237 55.567  133.692 1.00 165.12 ? 278 LEU A C   1 
ATOM   906   O O   . LEU A 1 279 ? 100.649 56.048  132.733 1.00 130.44 ? 278 LEU A O   1 
ATOM   907   C CB  . LEU A 1 279 ? 103.714 54.738  133.697 1.00 148.26 ? 278 LEU A CB  1 
ATOM   908   C CG  . LEU A 1 279 ? 104.024 54.479  132.243 1.00 194.97 ? 278 LEU A CG  1 
ATOM   909   C CD1 . LEU A 1 279 ? 105.400 53.846  132.108 1.00 208.29 ? 278 LEU A CD1 1 
ATOM   910   C CD2 . LEU A 1 279 ? 102.919 53.627  131.613 1.00 268.51 ? 278 LEU A CD2 1 
ATOM   911   N N   . GLN A 1 280 ? 100.608 54.779  134.563 1.00 178.76 ? 279 GLN A N   1 
ATOM   912   C CA  . GLN A 1 280 ? 99.166  54.551  134.480 1.00 174.21 ? 279 GLN A CA  1 
ATOM   913   C C   . GLN A 1 280 ? 98.414  55.818  134.896 1.00 143.62 ? 279 GLN A C   1 
ATOM   914   O O   . GLN A 1 280 ? 98.771  56.393  135.964 1.00 124.09 ? 279 GLN A O   1 
ATOM   915   C CB  . GLN A 1 280 ? 98.790  53.370  135.379 1.00 218.97 ? 279 GLN A CB  1 
ATOM   916   C CG  . GLN A 1 280 ? 97.294  53.099  135.479 1.00 253.54 ? 279 GLN A CG  1 
ATOM   917   C CD  . GLN A 1 280 ? 96.997  51.861  136.290 1.00 323.77 ? 279 GLN A CD  1 
ATOM   918   O OE1 . GLN A 1 280 ? 97.683  51.547  137.263 1.00 335.90 ? 279 GLN A OE1 1 
ATOM   919   N NE2 . GLN A 1 280 ? 95.963  51.134  135.892 1.00 385.39 ? 279 GLN A NE2 1 
ATOM   920   N N   . ILE A 1 281 ? 97.389  56.230  134.078 1.00 103.33 ? 280 ILE A N   1 
ATOM   921   C CA  . ILE A 1 281 ? 96.585  57.434  134.430 1.00 129.31 ? 280 ILE A CA  1 
ATOM   922   C C   . ILE A 1 281 ? 95.556  57.093  135.516 1.00 131.75 ? 280 ILE A C   1 
ATOM   923   O O   . ILE A 1 281 ? 95.090  55.952  135.606 1.00 192.70 ? 280 ILE A O   1 
ATOM   924   C CB  . ILE A 1 281 ? 95.942  58.173  133.224 1.00 94.35  ? 280 ILE A CB  1 
ATOM   925   C CG1 . ILE A 1 281 ? 94.864  57.367  132.536 1.00 147.07 ? 280 ILE A CG1 1 
ATOM   926   C CG2 . ILE A 1 281 ? 97.005  58.513  132.187 1.00 174.08 ? 280 ILE A CG2 1 
ATOM   927   C CD1 . ILE A 1 281 ? 93.517  57.776  132.932 1.00 193.22 ? 280 ILE A CD1 1 
ATOM   928   N N   . ASP A 1 282 ? 95.220  58.100  136.332 1.00 114.96 ? 281 ASP A N   1 
ATOM   929   C CA  . ASP A 1 282 ? 94.209  58.002  137.371 1.00 182.26 ? 281 ASP A CA  1 
ATOM   930   C C   . ASP A 1 282 ? 92.853  57.931  136.689 1.00 191.69 ? 281 ASP A C   1 
ATOM   931   O O   . ASP A 1 282 ? 92.475  58.922  136.054 1.00 202.14 ? 281 ASP A O   1 
ATOM   932   C CB  . ASP A 1 282 ? 94.290  59.201  138.328 1.00 276.93 ? 281 ASP A CB  1 
ATOM   933   C CG  . ASP A 1 282 ? 93.345  59.181  139.526 1.00 325.55 ? 281 ASP A CG  1 
ATOM   934   O OD1 . ASP A 1 282 ? 92.570  58.244  139.654 1.00 324.13 ? 281 ASP A OD1 1 
ATOM   935   O OD2 . ASP A 1 282 ? 93.389  60.117  140.330 1.00 395.53 ? 281 ASP A OD2 1 
ATOM   936   N N   . PRO A 1 283 ? 92.104  56.795  136.794 1.00 182.48 ? 282 PRO A N   1 
ATOM   937   C CA  . PRO A 1 283 ? 90.945  56.545  135.944 1.00 183.87 ? 282 PRO A CA  1 
ATOM   938   C C   . PRO A 1 283 ? 89.811  57.561  136.031 1.00 188.35 ? 282 PRO A C   1 
ATOM   939   O O   . PRO A 1 283 ? 89.025  57.599  135.079 1.00 165.92 ? 282 PRO A O   1 
ATOM   940   C CB  . PRO A 1 283 ? 90.441  55.159  136.399 1.00 218.17 ? 282 PRO A CB  1 
ATOM   941   C CG  . PRO A 1 283 ? 90.978  54.969  137.783 1.00 177.86 ? 282 PRO A CG  1 
ATOM   942   C CD  . PRO A 1 283 ? 92.320  55.664  137.712 1.00 198.17 ? 282 PRO A CD  1 
ATOM   943   N N   . ASN A 1 284 ? 89.734  58.361  137.120 1.00 206.60 ? 283 ASN A N   1 
ATOM   944   C CA  . ASN A 1 284 ? 88.770  59.452  137.252 1.00 218.05 ? 283 ASN A CA  1 
ATOM   945   C C   . ASN A 1 284 ? 88.765  60.352  136.017 1.00 191.85 ? 283 ASN A C   1 
ATOM   946   O O   . ASN A 1 284 ? 87.704  60.796  135.594 1.00 187.42 ? 283 ASN A O   1 
ATOM   947   C CB  . ASN A 1 284 ? 89.021  60.277  138.517 1.00 202.51 ? 283 ASN A CB  1 
ATOM   948   C CG  . ASN A 1 284 ? 88.776  59.476  139.777 1.00 277.38 ? 283 ASN A CG  1 
ATOM   949   O OD1 . ASN A 1 284 ? 88.392  58.307  139.711 1.00 280.45 ? 283 ASN A OD1 1 
ATOM   950   N ND2 . ASN A 1 284 ? 88.996  60.095  140.925 1.00 338.83 ? 283 ASN A ND2 1 
ATOM   951   N N   . PHE A 1 285 ? 89.951  60.607  135.449 1.00 170.68 ? 284 PHE A N   1 
ATOM   952   C CA  . PHE A 1 285 ? 90.113  61.500  134.311 1.00 181.67 ? 284 PHE A CA  1 
ATOM   953   C C   . PHE A 1 285 ? 89.873  60.804  132.974 1.00 175.10 ? 284 PHE A C   1 
ATOM   954   O O   . PHE A 1 285 ? 89.789  61.505  131.981 1.00 133.23 ? 284 PHE A O   1 
ATOM   955   C CB  . PHE A 1 285 ? 91.508  62.112  134.293 1.00 173.51 ? 284 PHE A CB  1 
ATOM   956   C CG  . PHE A 1 285 ? 91.894  62.812  135.571 1.00 149.08 ? 284 PHE A CG  1 
ATOM   957   C CD1 . PHE A 1 285 ? 91.112  63.850  136.051 1.00 182.58 ? 284 PHE A CD1 1 
ATOM   958   C CD2 . PHE A 1 285 ? 93.038  62.451  136.273 1.00 154.11 ? 284 PHE A CD2 1 
ATOM   959   C CE1 . PHE A 1 285 ? 91.444  64.515  137.224 1.00 212.72 ? 284 PHE A CE1 1 
ATOM   960   C CE2 . PHE A 1 285 ? 93.367  63.111  137.444 1.00 141.68 ? 284 PHE A CE2 1 
ATOM   961   C CZ  . PHE A 1 285 ? 92.575  64.145  137.915 1.00 189.96 ? 284 PHE A CZ  1 
ATOM   962   N N   . GLY A 1 286 ? 89.748  59.475  132.919 1.00 156.49 ? 285 GLY A N   1 
ATOM   963   C CA  . GLY A 1 286 ? 89.414  58.789  131.674 1.00 183.69 ? 285 GLY A CA  1 
ATOM   964   C C   . GLY A 1 286 ? 90.199  57.496  131.475 1.00 179.78 ? 285 GLY A C   1 
ATOM   965   O O   . GLY A 1 286 ? 90.243  56.658  132.380 1.00 182.56 ? 285 GLY A O   1 
ATOM   966   N N   . SER A 1 287 ? 90.814  57.373  130.283 1.00 169.28 ? 286 SER A N   1 
ATOM   967   C CA  . SER A 1 287 ? 91.632  56.244  129.843 1.00 170.44 ? 286 SER A CA  1 
ATOM   968   C C   . SER A 1 287 ? 92.746  56.755  128.938 1.00 138.87 ? 286 SER A C   1 
ATOM   969   O O   . SER A 1 287 ? 92.626  57.875  128.423 1.00 99.81  ? 286 SER A O   1 
ATOM   970   C CB  . SER A 1 287 ? 90.798  55.290  129.070 1.00 238.85 ? 286 SER A CB  1 
ATOM   971   O OG  . SER A 1 287 ? 90.325  55.912  127.869 1.00 249.09 ? 286 SER A OG  1 
ATOM   972   N N   . LYS A 1 288 ? 93.820  55.974  128.720 1.00 141.35 ? 287 LYS A N   1 
ATOM   973   C CA  . LYS A 1 288 ? 94.838  56.440  127.777 1.00 171.16 ? 287 LYS A CA  1 
ATOM   974   C C   . LYS A 1 288 ? 94.219  56.674  126.385 1.00 160.36 ? 287 LYS A C   1 
ATOM   975   O O   . LYS A 1 288 ? 94.671  57.546  125.635 1.00 162.73 ? 287 LYS A O   1 
ATOM   976   C CB  . LYS A 1 288 ? 96.051  55.500  127.725 1.00 165.86 ? 287 LYS A CB  1 
ATOM   977   C CG  . LYS A 1 288 ? 97.088  55.949  126.696 1.00 183.64 ? 287 LYS A CG  1 
ATOM   978   C CD  . LYS A 1 288 ? 98.548  55.676  127.012 1.00 215.99 ? 287 LYS A CD  1 
ATOM   979   C CE  . LYS A 1 288 ? 99.393  55.395  125.773 1.00 272.72 ? 287 LYS A CE  1 
ATOM   980   N NZ  . LYS A 1 288 ? 99.210  56.345  124.648 1.00 265.50 ? 287 LYS A NZ  1 
ATOM   981   N N   . GLU A 1 289 ? 93.179  55.905  126.046 1.00 168.46 ? 288 GLU A N   1 
ATOM   982   C CA  . GLU A 1 289 ? 92.443  56.067  124.797 1.00 164.22 ? 288 GLU A CA  1 
ATOM   983   C C   . GLU A 1 289 ? 91.759  57.431  124.741 1.00 152.82 ? 288 GLU A C   1 
ATOM   984   O O   . GLU A 1 289 ? 91.654  57.976  123.643 1.00 178.45 ? 288 GLU A O   1 
ATOM   985   C CB  . GLU A 1 289 ? 91.452  54.911  124.629 1.00 231.42 ? 288 GLU A CB  1 
ATOM   986   C CG  . GLU A 1 289 ? 92.133  53.578  124.312 1.00 327.86 ? 288 GLU A CG  1 
ATOM   987   C CD  . GLU A 1 289 ? 92.972  52.931  125.410 1.00 393.38 ? 288 GLU A CD  1 
ATOM   988   O OE1 . GLU A 1 289 ? 92.721  53.209  126.602 1.00 408.04 ? 288 GLU A OE1 1 
ATOM   989   O OE2 . GLU A 1 289 ? 93.887  52.151  125.076 1.00 425.25 ? 288 GLU A OE2 1 
ATOM   990   N N   . ASP A 1 290 ? 91.295  57.981  125.882 1.00 142.98 ? 289 ASP A N   1 
ATOM   991   C CA  . ASP A 1 290 ? 90.830  59.366  125.917 1.00 187.49 ? 289 ASP A CA  1 
ATOM   992   C C   . ASP A 1 290 ? 91.998  60.333  125.762 1.00 155.96 ? 289 ASP A C   1 
ATOM   993   O O   . ASP A 1 290 ? 91.894  61.302  125.002 1.00 135.71 ? 289 ASP A O   1 
ATOM   994   C CB  . ASP A 1 290 ? 90.077  59.705  127.203 1.00 234.41 ? 289 ASP A CB  1 
ATOM   995   C CG  . ASP A 1 290 ? 88.881  58.808  127.438 1.00 260.55 ? 289 ASP A CG  1 
ATOM   996   O OD1 . ASP A 1 290 ? 87.958  58.832  126.601 1.00 319.59 ? 289 ASP A OD1 1 
ATOM   997   O OD2 . ASP A 1 290 ? 88.898  58.092  128.447 1.00 243.09 ? 289 ASP A OD2 1 
ATOM   998   N N   . PHE A 1 291 ? 93.089  60.066  126.501 1.00 145.29 ? 290 PHE A N   1 
ATOM   999   C CA  . PHE A 1 291 ? 94.247  60.947  126.526 1.00 160.45 ? 290 PHE A CA  1 
ATOM   1000  C C   . PHE A 1 291 ? 94.741  61.167  125.093 1.00 154.14 ? 290 PHE A C   1 
ATOM   1001  O O   . PHE A 1 291 ? 94.951  62.310  124.679 1.00 156.58 ? 290 PHE A O   1 
ATOM   1002  C CB  . PHE A 1 291 ? 95.340  60.414  127.470 1.00 154.50 ? 290 PHE A CB  1 
ATOM   1003  C CG  . PHE A 1 291 ? 96.468  61.412  127.620 1.00 173.69 ? 290 PHE A CG  1 
ATOM   1004  C CD1 . PHE A 1 291 ? 96.331  62.547  128.411 1.00 216.96 ? 290 PHE A CD1 1 
ATOM   1005  C CD2 . PHE A 1 291 ? 97.659  61.255  126.934 1.00 136.86 ? 290 PHE A CD2 1 
ATOM   1006  C CE1 . PHE A 1 291 ? 97.363  63.473  128.526 1.00 201.83 ? 290 PHE A CE1 1 
ATOM   1007  C CE2 . PHE A 1 291 ? 98.684  62.175  127.057 1.00 164.05 ? 290 PHE A CE2 1 
ATOM   1008  C CZ  . PHE A 1 291 ? 98.543  63.284  127.848 1.00 189.64 ? 290 PHE A CZ  1 
ATOM   1009  N N   . ASP A 1 292 ? 94.911  60.063  124.355 1.00 124.16 ? 291 ASP A N   1 
ATOM   1010  C CA  . ASP A 1 292 ? 95.377  60.117  122.984 1.00 155.31 ? 291 ASP A CA  1 
ATOM   1011  C C   . ASP A 1 292 ? 94.365  60.839  122.097 1.00 156.99 ? 291 ASP A C   1 
ATOM   1012  O O   . ASP A 1 292 ? 94.778  61.540  121.181 1.00 182.92 ? 291 ASP A O   1 
ATOM   1013  C CB  . ASP A 1 292 ? 95.687  58.706  122.472 1.00 206.22 ? 291 ASP A CB  1 
ATOM   1014  C CG  . ASP A 1 292 ? 96.846  58.020  123.180 1.00 268.65 ? 291 ASP A CG  1 
ATOM   1015  O OD1 . ASP A 1 292 ? 97.691  58.732  123.743 1.00 307.14 ? 291 ASP A OD1 1 
ATOM   1016  O OD2 . ASP A 1 292 ? 96.896  56.768  123.175 1.00 325.32 ? 291 ASP A OD2 1 
ATOM   1017  N N   . SER A 1 293 ? 93.069  60.676  122.366 1.00 141.15 ? 292 SER A N   1 
ATOM   1018  C CA  . SER A 1 293 ? 92.029  61.295  121.564 1.00 158.22 ? 292 SER A CA  1 
ATOM   1019  C C   . SER A 1 293 ? 92.120  62.807  121.684 1.00 159.61 ? 292 SER A C   1 
ATOM   1020  O O   . SER A 1 293 ? 92.007  63.502  120.686 1.00 163.31 ? 292 SER A O   1 
ATOM   1021  C CB  . SER A 1 293 ? 90.655  60.784  121.978 1.00 192.40 ? 292 SER A CB  1 
ATOM   1022  O OG  . SER A 1 293 ? 89.639  61.281  121.129 1.00 283.54 ? 292 SER A OG  1 
ATOM   1023  N N   . LEU A 1 294 ? 92.303  63.287  122.927 1.00 178.57 ? 293 LEU A N   1 
ATOM   1024  C CA  . LEU A 1 294 ? 92.598  64.683  123.232 1.00 159.11 ? 293 LEU A CA  1 
ATOM   1025  C C   . LEU A 1 294 ? 93.859  65.125  122.516 1.00 115.73 ? 293 LEU A C   1 
ATOM   1026  O O   . LEU A 1 294 ? 93.845  66.094  121.751 1.00 114.59 ? 293 LEU A O   1 
ATOM   1027  C CB  . LEU A 1 294 ? 92.777  64.866  124.746 1.00 124.54 ? 293 LEU A CB  1 
ATOM   1028  C CG  . LEU A 1 294 ? 93.514  66.113  125.200 1.00 141.43 ? 293 LEU A CG  1 
ATOM   1029  C CD1 . LEU A 1 294 ? 92.842  67.415  124.725 1.00 122.91 ? 293 LEU A CD1 1 
ATOM   1030  C CD2 . LEU A 1 294 ? 93.619  66.040  126.715 1.00 152.00 ? 293 LEU A CD2 1 
ATOM   1031  N N   . LEU A 1 295 ? 94.933  64.405  122.803 1.00 108.83 ? 294 LEU A N   1 
ATOM   1032  C CA  . LEU A 1 295 ? 96.254  64.849  122.407 1.00 124.79 ? 294 LEU A CA  1 
ATOM   1033  C C   . LEU A 1 295 ? 96.318  64.979  120.866 1.00 140.21 ? 294 LEU A C   1 
ATOM   1034  O O   . LEU A 1 295 ? 96.922  65.924  120.353 1.00 103.33 ? 294 LEU A O   1 
ATOM   1035  C CB  . LEU A 1 295 ? 97.222  63.881  123.102 1.00 111.53 ? 294 LEU A CB  1 
ATOM   1036  C CG  . LEU A 1 295 ? 98.684  63.967  122.680 1.00 135.55 ? 294 LEU A CG  1 
ATOM   1037  C CD1 . LEU A 1 295 ? 99.253  65.333  122.947 1.00 194.28 ? 294 LEU A CD1 1 
ATOM   1038  C CD2 . LEU A 1 295 ? 99.508  62.918  123.386 1.00 137.72 ? 294 LEU A CD2 1 
ATOM   1039  N N   . GLN A 1 296 ? 95.680  64.053  120.131 1.00 153.41 ? 295 GLN A N   1 
ATOM   1040  C CA  . GLN A 1 296 ? 95.550  64.105  118.677 1.00 171.33 ? 295 GLN A CA  1 
ATOM   1041  C C   . GLN A 1 296 ? 94.697  65.294  118.241 1.00 138.74 ? 295 GLN A C   1 
ATOM   1042  O O   . GLN A 1 296 ? 94.980  65.895  117.207 1.00 209.00 ? 295 GLN A O   1 
ATOM   1043  C CB  . GLN A 1 296 ? 94.973  62.778  118.184 1.00 189.40 ? 295 GLN A CB  1 
ATOM   1044  C CG  . GLN A 1 296 ? 94.956  62.597  116.679 1.00 266.98 ? 295 GLN A CG  1 
ATOM   1045  C CD  . GLN A 1 296 ? 94.531  61.195  116.296 1.00 353.65 ? 295 GLN A CD  1 
ATOM   1046  O OE1 . GLN A 1 296 ? 94.210  60.360  117.143 1.00 314.30 ? 295 GLN A OE1 1 
ATOM   1047  N NE2 . GLN A 1 296 ? 94.525  60.923  114.999 1.00 435.74 ? 295 GLN A NE2 1 
ATOM   1048  N N   . SER A 1 297 ? 93.656  65.641  119.004 1.00 105.11 ? 296 SER A N   1 
ATOM   1049  C CA  . SER A 1 297 ? 92.842  66.826  118.712 1.00 162.07 ? 296 SER A CA  1 
ATOM   1050  C C   . SER A 1 297 ? 93.641  68.115  118.901 1.00 140.52 ? 296 SER A C   1 
ATOM   1051  O O   . SER A 1 297 ? 93.544  69.062  118.116 1.00 135.54 ? 296 SER A O   1 
ATOM   1052  C CB  . SER A 1 297 ? 91.565  66.873  119.533 1.00 142.22 ? 296 SER A CB  1 
ATOM   1053  O OG  . SER A 1 297 ? 90.818  65.682  119.375 1.00 141.75 ? 296 SER A OG  1 
ATOM   1054  N N   . ALA A 1 298 ? 94.436  68.128  119.958 1.00 132.41 ? 297 ALA A N   1 
ATOM   1055  C CA  . ALA A 1 298 ? 95.227  69.293  120.261 1.00 134.27 ? 297 ALA A CA  1 
ATOM   1056  C C   . ALA A 1 298 ? 96.253  69.487  119.142 1.00 128.02 ? 297 ALA A C   1 
ATOM   1057  O O   . ALA A 1 298 ? 96.428  70.616  118.697 1.00 133.83 ? 297 ALA A O   1 
ATOM   1058  C CB  . ALA A 1 298 ? 95.825  69.098  121.641 1.00 186.33 ? 297 ALA A CB  1 
ATOM   1059  N N   . LYS A 1 299 ? 96.946  68.412  118.691 1.00 136.91 ? 298 LYS A N   1 
ATOM   1060  C CA  . LYS A 1 299 ? 97.873  68.462  117.557 1.00 181.17 ? 298 LYS A CA  1 
ATOM   1061  C C   . LYS A 1 299 ? 97.162  69.064  116.358 1.00 127.41 ? 298 LYS A C   1 
ATOM   1062  O O   . LYS A 1 299 ? 97.714  69.979  115.731 1.00 197.54 ? 298 LYS A O   1 
ATOM   1063  C CB  . LYS A 1 299 ? 98.503  67.101  117.191 1.00 194.94 ? 298 LYS A CB  1 
ATOM   1064  C CG  . LYS A 1 299 ? 99.860  66.821  117.841 1.00 298.07 ? 298 LYS A CG  1 
ATOM   1065  C CD  . LYS A 1 299 ? 99.820  66.642  119.353 1.00 378.66 ? 298 LYS A CD  1 
ATOM   1066  C CE  . LYS A 1 299 ? 101.047 67.121  120.107 1.00 421.63 ? 298 LYS A CE  1 
ATOM   1067  N NZ  . LYS A 1 299 ? 102.274 66.329  119.871 1.00 424.27 ? 298 LYS A NZ  1 
ATOM   1068  N N   . LYS A 1 300 ? 95.969  68.541  116.058 1.00 160.86 ? 299 LYS A N   1 
ATOM   1069  C CA  . LYS A 1 300 ? 95.129  69.002  114.954 1.00 244.91 ? 299 LYS A CA  1 
ATOM   1070  C C   . LYS A 1 300 ? 94.853  70.513  115.068 1.00 170.36 ? 299 LYS A C   1 
ATOM   1071  O O   . LYS A 1 300 ? 94.806  71.194  114.033 1.00 154.00 ? 299 LYS A O   1 
ATOM   1072  C CB  . LYS A 1 300 ? 93.874  68.111  114.862 1.00 249.60 ? 299 LYS A CB  1 
ATOM   1073  C CG  . LYS A 1 300 ? 92.709  68.608  114.019 1.00 279.27 ? 299 LYS A CG  1 
ATOM   1074  C CD  . LYS A 1 300 ? 93.023  68.761  112.544 1.00 369.82 ? 299 LYS A CD  1 
ATOM   1075  C CE  . LYS A 1 300 ? 91.868  69.349  111.757 1.00 404.39 ? 299 LYS A CE  1 
ATOM   1076  N NZ  . LYS A 1 300 ? 92.229  69.602  110.341 1.00 392.31 ? 299 LYS A NZ  1 
ATOM   1077  N N   . LYS A 1 301 ? 94.676  71.038  116.292 1.00 128.33 ? 300 LYS A N   1 
ATOM   1078  C CA  . LYS A 1 301 ? 94.329  72.449  116.489 1.00 149.24 ? 300 LYS A CA  1 
ATOM   1079  C C   . LYS A 1 301 ? 95.546  73.353  116.817 1.00 138.29 ? 300 LYS A C   1 
ATOM   1080  O O   . LYS A 1 301 ? 95.341  74.521  117.162 1.00 155.91 ? 300 LYS A O   1 
ATOM   1081  C CB  . LYS A 1 301 ? 93.212  72.476  117.558 1.00 149.42 ? 300 LYS A CB  1 
ATOM   1082  C CG  . LYS A 1 301 ? 92.111  73.463  117.291 1.00 152.74 ? 300 LYS A CG  1 
ATOM   1083  C CD  . LYS A 1 301 ? 90.970  73.475  118.285 1.00 159.62 ? 300 LYS A CD  1 
ATOM   1084  C CE  . LYS A 1 301 ? 89.699  74.087  117.704 1.00 250.24 ? 300 LYS A CE  1 
ATOM   1085  N NZ  . LYS A 1 301 ? 89.958  75.379  116.997 1.00 313.87 ? 300 LYS A NZ  1 
ATOM   1086  N N   . SER A 1 302 ? 96.797  72.829  116.754 1.00 140.89 ? 301 SER A N   1 
ATOM   1087  C CA  . SER A 1 302 ? 98.068  73.547  116.972 1.00 149.61 ? 301 SER A CA  1 
ATOM   1088  C C   . SER A 1 302 ? 98.356  73.973  118.435 1.00 156.14 ? 301 SER A C   1 
ATOM   1089  O O   . SER A 1 302 ? 99.198  74.834  118.712 1.00 161.51 ? 301 SER A O   1 
ATOM   1090  C CB  . SER A 1 302 ? 98.207  74.712  116.022 1.00 161.43 ? 301 SER A CB  1 
ATOM   1091  O OG  . SER A 1 302 ? 98.121  74.251  114.682 1.00 245.24 ? 301 SER A OG  1 
ATOM   1092  N N   . ILE A 1 303 ? 97.692  73.331  119.391 1.00 110.26 ? 302 ILE A N   1 
ATOM   1093  C CA  . ILE A 1 303 ? 97.964  73.430  120.814 1.00 80.10  ? 302 ILE A CA  1 
ATOM   1094  C C   . ILE A 1 303 ? 98.886  72.295  121.239 1.00 92.30  ? 302 ILE A C   1 
ATOM   1095  O O   . ILE A 1 303 ? 98.440  71.169  121.387 1.00 87.01  ? 302 ILE A O   1 
ATOM   1096  C CB  . ILE A 1 303 ? 96.581  73.370  121.493 1.00 77.79  ? 302 ILE A CB  1 
ATOM   1097  C CG1 . ILE A 1 303 ? 95.845  74.650  121.032 1.00 96.97  ? 302 ILE A CG1 1 
ATOM   1098  C CG2 . ILE A 1 303 ? 96.609  73.181  123.036 1.00 96.31  ? 302 ILE A CG2 1 
ATOM   1099  C CD1 . ILE A 1 303 ? 94.608  75.009  121.842 1.00 103.73 ? 302 ILE A CD1 1 
ATOM   1100  N N   . ARG A 1 304 ? 100.170 72.550  121.439 1.00 99.87  ? 303 ARG A N   1 
ATOM   1101  C CA  . ARG A 1 304 ? 101.017 71.516  121.998 1.00 111.90 ? 303 ARG A CA  1 
ATOM   1102  C C   . ARG A 1 304 ? 100.539 71.216  123.431 1.00 75.45  ? 303 ARG A C   1 
ATOM   1103  O O   . ARG A 1 304 ? 100.119 72.140  124.138 1.00 69.66  ? 303 ARG A O   1 
ATOM   1104  C CB  . ARG A 1 304 ? 102.506 71.934  121.938 1.00 133.44 ? 303 ARG A CB  1 
ATOM   1105  C CG  . ARG A 1 304 ? 103.219 71.740  120.595 1.00 135.68 ? 303 ARG A CG  1 
ATOM   1106  C CD  . ARG A 1 304 ? 102.792 72.715  119.566 1.00 146.59 ? 303 ARG A CD  1 
ATOM   1107  N NE  . ARG A 1 304 ? 103.712 72.717  118.439 1.00 142.25 ? 303 ARG A NE  1 
ATOM   1108  C CZ  . ARG A 1 304 ? 103.696 73.660  117.494 1.00 276.19 ? 303 ARG A CZ  1 
ATOM   1109  N NH1 . ARG A 1 304 ? 104.576 73.637  116.504 1.00 326.56 ? 303 ARG A NH1 1 
ATOM   1110  N NH2 . ARG A 1 304 ? 102.789 74.630  117.548 1.00 304.43 ? 303 ARG A NH2 1 
ATOM   1111  N N   . VAL A 1 305 ? 100.659 69.967  123.885 1.00 62.00  ? 304 VAL A N   1 
ATOM   1112  C CA  . VAL A 1 305 ? 100.352 69.618  125.267 1.00 66.62  ? 304 VAL A CA  1 
ATOM   1113  C C   . VAL A 1 305 ? 101.495 69.047  126.127 1.00 67.78  ? 304 VAL A C   1 
ATOM   1114  O O   . VAL A 1 305 ? 102.037 67.974  125.838 1.00 91.47  ? 304 VAL A O   1 
ATOM   1115  C CB  . VAL A 1 305 ? 99.286  68.539  125.186 1.00 70.00  ? 304 VAL A CB  1 
ATOM   1116  C CG1 . VAL A 1 305 ? 99.000  67.764  126.541 1.00 49.64  ? 304 VAL A CG1 1 
ATOM   1117  C CG2 . VAL A 1 305 ? 98.118  69.207  124.447 1.00 73.88  ? 304 VAL A CG2 1 
ATOM   1118  N N   . ILE A 1 306 ? 101.805 69.749  127.215 1.00 58.98  ? 305 ILE A N   1 
ATOM   1119  C CA  . ILE A 1 306 ? 102.673 69.267  128.278 1.00 70.44  ? 305 ILE A CA  1 
ATOM   1120  C C   . ILE A 1 306 ? 101.928 68.595  129.428 1.00 57.19  ? 305 ILE A C   1 
ATOM   1121  O O   . ILE A 1 306 ? 100.890 68.998  129.860 1.00 58.23  ? 305 ILE A O   1 
ATOM   1122  C CB  . ILE A 1 306 ? 103.410 70.481  128.805 1.00 55.20  ? 305 ILE A CB  1 
ATOM   1123  C CG1 . ILE A 1 306 ? 104.283 71.083  127.727 1.00 49.86  ? 305 ILE A CG1 1 
ATOM   1124  C CG2 . ILE A 1 306 ? 104.192 70.162  130.055 1.00 57.94  ? 305 ILE A CG2 1 
ATOM   1125  C CD1 . ILE A 1 306 ? 104.337 72.632  127.973 1.00 97.59  ? 305 ILE A CD1 1 
ATOM   1126  N N   . LEU A 1 307 ? 102.502 67.570  129.980 1.00 51.98  ? 306 LEU A N   1 
ATOM   1127  C CA  . LEU A 1 307 ? 101.897 66.851  131.068 1.00 56.60  ? 306 LEU A CA  1 
ATOM   1128  C C   . LEU A 1 307 ? 102.770 67.099  132.295 1.00 56.87  ? 306 LEU A C   1 
ATOM   1129  O O   . LEU A 1 307 ? 103.985 67.130  132.243 1.00 56.16  ? 306 LEU A O   1 
ATOM   1130  C CB  . LEU A 1 307 ? 101.856 65.373  130.637 1.00 68.49  ? 306 LEU A CB  1 
ATOM   1131  C CG  . LEU A 1 307 ? 101.885 64.294  131.711 1.00 64.49  ? 306 LEU A CG  1 
ATOM   1132  C CD1 . LEU A 1 307 ? 100.519 64.167  132.250 1.00 117.77 ? 306 LEU A CD1 1 
ATOM   1133  C CD2 . LEU A 1 307 ? 102.284 62.962  131.126 1.00 88.48  ? 306 LEU A CD2 1 
ATOM   1134  N N   . ASP A 1 308 ? 102.140 67.257  133.432 1.00 77.12  ? 307 ASP A N   1 
ATOM   1135  C CA  . ASP A 1 308 ? 102.823 67.545  134.683 1.00 68.76  ? 307 ASP A CA  1 
ATOM   1136  C C   . ASP A 1 308 ? 103.070 66.230  135.414 1.00 82.86  ? 307 ASP A C   1 
ATOM   1137  O O   . ASP A 1 308 ? 102.143 65.500  135.756 1.00 102.35 ? 307 ASP A O   1 
ATOM   1138  C CB  . ASP A 1 308 ? 101.930 68.461  135.523 1.00 87.34  ? 307 ASP A CB  1 
ATOM   1139  C CG  . ASP A 1 308 ? 102.602 69.015  136.748 1.00 121.12 ? 307 ASP A CG  1 
ATOM   1140  O OD1 . ASP A 1 308 ? 103.539 68.362  137.248 1.00 150.66 ? 307 ASP A OD1 1 
ATOM   1141  O OD2 . ASP A 1 308 ? 102.152 70.108  137.204 1.00 192.63 ? 307 ASP A OD2 1 
ATOM   1142  N N   . LEU A 1 309 ? 104.317 65.925  135.721 1.00 94.18  ? 308 LEU A N   1 
ATOM   1143  C CA  . LEU A 1 309 ? 104.655 64.637  136.308 1.00 86.99  ? 308 LEU A CA  1 
ATOM   1144  C C   . LEU A 1 309 ? 105.044 64.723  137.780 1.00 92.56  ? 308 LEU A C   1 
ATOM   1145  O O   . LEU A 1 309 ? 105.617 63.773  138.293 1.00 116.37 ? 308 LEU A O   1 
ATOM   1146  C CB  . LEU A 1 309 ? 105.850 64.092  135.542 1.00 86.78  ? 308 LEU A CB  1 
ATOM   1147  C CG  . LEU A 1 309 ? 105.550 63.740  134.101 1.00 97.86  ? 308 LEU A CG  1 
ATOM   1148  C CD1 . LEU A 1 309 ? 106.871 63.431  133.460 1.00 124.93 ? 308 LEU A CD1 1 
ATOM   1149  C CD2 . LEU A 1 309 ? 104.613 62.569  134.069 1.00 125.39 ? 308 LEU A CD2 1 
ATOM   1150  N N   . THR A 1 310 ? 104.750 65.827  138.469 1.00 97.13  ? 309 THR A N   1 
ATOM   1151  C CA  . THR A 1 310 ? 105.185 65.954  139.845 1.00 97.37  ? 309 THR A CA  1 
ATOM   1152  C C   . THR A 1 310 ? 104.525 64.818  140.647 1.00 93.55  ? 309 THR A C   1 
ATOM   1153  O O   . THR A 1 310 ? 103.312 64.734  140.723 1.00 82.00  ? 309 THR A O   1 
ATOM   1154  C CB  . THR A 1 310 ? 104.910 67.352  140.378 1.00 92.68  ? 309 THR A CB  1 
ATOM   1155  O OG1 . THR A 1 310 ? 105.622 67.408  141.614 1.00 224.14 ? 309 THR A OG1 1 
ATOM   1156  C CG2 . THR A 1 310 ? 103.472 67.624  140.699 1.00 96.11  ? 309 THR A CG2 1 
ATOM   1157  N N   . PRO A 1 311 ? 105.298 63.876  141.236 1.00 101.64 ? 310 PRO A N   1 
ATOM   1158  C CA  . PRO A 1 311 ? 104.727 62.583  141.677 1.00 83.89  ? 310 PRO A CA  1 
ATOM   1159  C C   . PRO A 1 311 ? 103.571 62.643  142.675 1.00 94.22  ? 310 PRO A C   1 
ATOM   1160  O O   . PRO A 1 311 ? 102.514 62.143  142.350 1.00 128.13 ? 310 PRO A O   1 
ATOM   1161  C CB  . PRO A 1 311 ? 105.920 61.894  142.317 1.00 113.42 ? 310 PRO A CB  1 
ATOM   1162  C CG  . PRO A 1 311 ? 107.126 62.579  141.653 1.00 120.16 ? 310 PRO A CG  1 
ATOM   1163  C CD  . PRO A 1 311 ? 106.753 64.019  141.474 1.00 88.67  ? 310 PRO A CD  1 
ATOM   1164  N N   . ASN A 1 312 ? 103.731 63.246  143.864 1.00 94.95  ? 311 ASN A N   1 
ATOM   1165  C CA  . ASN A 1 312 ? 102.814 63.068  144.975 1.00 125.47 ? 311 ASN A CA  1 
ATOM   1166  C C   . ASN A 1 312 ? 101.797 64.203  144.978 1.00 119.71 ? 311 ASN A C   1 
ATOM   1167  O O   . ASN A 1 312 ? 101.550 64.813  146.017 1.00 152.02 ? 311 ASN A O   1 
ATOM   1168  C CB  . ASN A 1 312 ? 103.589 63.028  146.297 1.00 128.63 ? 311 ASN A CB  1 
ATOM   1169  C CG  . ASN A 1 312 ? 102.749 62.692  147.516 1.00 180.93 ? 311 ASN A CG  1 
ATOM   1170  O OD1 . ASN A 1 312 ? 101.740 61.986  147.429 1.00 203.74 ? 311 ASN A OD1 1 
ATOM   1171  N ND2 . ASN A 1 312 ? 103.154 63.192  148.677 1.00 243.96 ? 311 ASN A ND2 1 
ATOM   1172  N N   . TYR A 1 313 ? 101.182 64.486  143.840 1.00 88.39  ? 312 TYR A N   1 
ATOM   1173  C CA  . TYR A 1 313 ? 100.437 65.721  143.709 1.00 120.61 ? 312 TYR A CA  1 
ATOM   1174  C C   . TYR A 1 313 ? 99.165  65.817  144.558 1.00 144.72 ? 312 TYR A C   1 
ATOM   1175  O O   . TYR A 1 313 ? 98.685  66.943  144.730 1.00 165.99 ? 312 TYR A O   1 
ATOM   1176  C CB  . TYR A 1 313 ? 100.016 65.899  142.263 1.00 144.16 ? 312 TYR A CB  1 
ATOM   1177  C CG  . TYR A 1 313 ? 99.040  64.898  141.673 1.00 114.42 ? 312 TYR A CG  1 
ATOM   1178  C CD1 . TYR A 1 313 ? 99.490  63.735  141.086 1.00 119.22 ? 312 TYR A CD1 1 
ATOM   1179  C CD2 . TYR A 1 313 ? 97.680  65.128  141.689 1.00 165.03 ? 312 TYR A CD2 1 
ATOM   1180  C CE1 . TYR A 1 313 ? 98.623  62.825  140.512 1.00 140.38 ? 312 TYR A CE1 1 
ATOM   1181  C CE2 . TYR A 1 313 ? 96.795  64.217  141.127 1.00 193.85 ? 312 TYR A CE2 1 
ATOM   1182  C CZ  . TYR A 1 313 ? 97.270  63.057  140.537 1.00 157.89 ? 312 TYR A CZ  1 
ATOM   1183  O OH  . TYR A 1 313 ? 96.414  62.161  139.993 1.00 198.73 ? 312 TYR A OH  1 
ATOM   1184  N N   . ARG A 1 314 ? 98.615  64.695  145.065 1.00 108.20 ? 313 ARG A N   1 
ATOM   1185  C CA  . ARG A 1 314 ? 97.508  64.763  146.003 1.00 141.99 ? 313 ARG A CA  1 
ATOM   1186  C C   . ARG A 1 314 ? 97.979  64.934  147.449 1.00 168.70 ? 313 ARG A C   1 
ATOM   1187  O O   . ARG A 1 314 ? 97.124  65.115  148.330 1.00 204.00 ? 313 ARG A O   1 
ATOM   1188  C CB  . ARG A 1 314 ? 96.651  63.508  145.867 1.00 174.95 ? 313 ARG A CB  1 
ATOM   1189  C CG  . ARG A 1 314 ? 96.066  63.323  144.479 1.00 165.38 ? 313 ARG A CG  1 
ATOM   1190  C CD  . ARG A 1 314 ? 95.007  62.254  144.436 1.00 197.68 ? 313 ARG A CD  1 
ATOM   1191  N NE  . ARG A 1 314 ? 94.407  62.114  143.120 1.00 197.41 ? 313 ARG A NE  1 
ATOM   1192  C CZ  . ARG A 1 314 ? 93.583  62.982  142.519 1.00 217.81 ? 313 ARG A CZ  1 
ATOM   1193  N NH1 . ARG A 1 314 ? 93.110  62.692  141.316 1.00 253.14 ? 313 ARG A NH1 1 
ATOM   1194  N NH2 . ARG A 1 314 ? 93.225  64.126  143.091 1.00 206.31 ? 313 ARG A NH2 1 
ATOM   1195  N N   . GLY A 1 315 ? 99.306  64.893  147.697 1.00 140.11 ? 314 GLY A N   1 
ATOM   1196  C CA  . GLY A 1 315 ? 99.876  64.972  149.038 1.00 167.82 ? 314 GLY A CA  1 
ATOM   1197  C C   . GLY A 1 315 ? 100.327 66.375  149.449 1.00 189.22 ? 314 GLY A C   1 
ATOM   1198  O O   . GLY A 1 315 ? 100.006 67.375  148.801 1.00 222.01 ? 314 GLY A O   1 
ATOM   1199  N N   . GLU A 1 316 ? 101.077 66.418  150.557 1.00 180.94 ? 315 GLU A N   1 
ATOM   1200  C CA  . GLU A 1 316 ? 101.597 67.652  151.123 1.00 200.09 ? 315 GLU A CA  1 
ATOM   1201  C C   . GLU A 1 316 ? 102.919 68.004  150.442 1.00 180.53 ? 315 GLU A C   1 
ATOM   1202  O O   . GLU A 1 316 ? 103.085 69.134  149.978 1.00 251.06 ? 315 GLU A O   1 
ATOM   1203  C CB  . GLU A 1 316 ? 101.757 67.498  152.639 1.00 262.06 ? 315 GLU A CB  1 
ATOM   1204  C CG  . GLU A 1 316 ? 102.322 68.728  153.336 1.00 319.82 ? 315 GLU A CG  1 
ATOM   1205  C CD  . GLU A 1 316 ? 102.185 68.771  154.853 1.00 399.24 ? 315 GLU A CD  1 
ATOM   1206  O OE1 . GLU A 1 316 ? 101.770 67.756  155.454 1.00 456.41 ? 315 GLU A OE1 1 
ATOM   1207  O OE2 . GLU A 1 316 ? 102.494 69.830  155.435 1.00 433.56 ? 315 GLU A OE2 1 
ATOM   1208  N N   . ASN A 1 317 ? 103.845 67.035  150.397 1.00 148.46 ? 316 ASN A N   1 
ATOM   1209  C CA  . ASN A 1 317 ? 105.170 67.213  149.816 1.00 172.13 ? 316 ASN A CA  1 
ATOM   1210  C C   . ASN A 1 317 ? 105.246 66.481  148.480 1.00 153.62 ? 316 ASN A C   1 
ATOM   1211  O O   . ASN A 1 317 ? 105.110 65.261  148.460 1.00 169.83 ? 316 ASN A O   1 
ATOM   1212  C CB  . ASN A 1 317 ? 106.243 66.725  150.787 1.00 181.17 ? 316 ASN A CB  1 
ATOM   1213  C CG  . ASN A 1 317 ? 107.663 66.803  150.247 1.00 210.75 ? 316 ASN A CG  1 
ATOM   1214  O OD1 . ASN A 1 317 ? 107.888 66.821  149.037 1.00 147.12 ? 316 ASN A OD1 1 
ATOM   1215  N ND2 . ASN A 1 317 ? 108.651 66.823  151.130 1.00 267.07 ? 316 ASN A ND2 1 
ATOM   1216  N N   . SER A 1 318 ? 105.470 67.219  147.368 1.00 125.67 ? 317 SER A N   1 
ATOM   1217  C CA  . SER A 1 318 ? 105.175 66.674  146.053 1.00 161.98 ? 317 SER A CA  1 
ATOM   1218  C C   . SER A 1 318 ? 106.180 65.613  145.591 1.00 130.77 ? 317 SER A C   1 
ATOM   1219  O O   . SER A 1 318 ? 105.901 64.863  144.643 1.00 162.01 ? 317 SER A O   1 
ATOM   1220  C CB  . SER A 1 318 ? 105.021 67.744  145.040 1.00 221.81 ? 317 SER A CB  1 
ATOM   1221  O OG  . SER A 1 318 ? 103.932 68.603  145.405 1.00 243.94 ? 317 SER A OG  1 
ATOM   1222  N N   . TRP A 1 319 ? 107.333 65.509  146.238 1.00 92.09  ? 318 TRP A N   1 
ATOM   1223  C CA  . TRP A 1 319 ? 108.269 64.453  145.884 1.00 110.87 ? 318 TRP A CA  1 
ATOM   1224  C C   . TRP A 1 319 ? 108.381 63.338  146.929 1.00 146.47 ? 318 TRP A C   1 
ATOM   1225  O O   . TRP A 1 319 ? 109.294 62.519  146.840 1.00 125.00 ? 318 TRP A O   1 
ATOM   1226  C CB  . TRP A 1 319 ? 109.630 65.114  145.710 1.00 145.15 ? 318 TRP A CB  1 
ATOM   1227  C CG  . TRP A 1 319 ? 109.572 66.055  144.560 1.00 118.58 ? 318 TRP A CG  1 
ATOM   1228  C CD1 . TRP A 1 319 ? 109.356 67.391  144.607 1.00 153.85 ? 318 TRP A CD1 1 
ATOM   1229  C CD2 . TRP A 1 319 ? 109.736 65.708  143.186 1.00 97.55  ? 318 TRP A CD2 1 
ATOM   1230  N NE1 . TRP A 1 319 ? 109.381 67.906  143.348 1.00 159.84 ? 318 TRP A NE1 1 
ATOM   1231  C CE2 . TRP A 1 319 ? 109.618 66.901  142.462 1.00 128.95 ? 318 TRP A CE2 1 
ATOM   1232  C CE3 . TRP A 1 319 ? 109.981 64.527  142.505 1.00 111.92 ? 318 TRP A CE3 1 
ATOM   1233  C CZ2 . TRP A 1 319 ? 109.725 66.946  141.087 1.00 112.36 ? 318 TRP A CZ2 1 
ATOM   1234  C CZ3 . TRP A 1 319 ? 110.099 64.564  141.147 1.00 142.52 ? 318 TRP A CZ3 1 
ATOM   1235  C CH2 . TRP A 1 319 ? 109.961 65.762  140.451 1.00 134.33 ? 318 TRP A CH2 1 
ATOM   1236  N N   . PHE A 1 320 ? 107.474 63.312  147.911 1.00 145.62 ? 319 PHE A N   1 
ATOM   1237  C CA  . PHE A 1 320 ? 107.581 62.470  149.090 1.00 178.33 ? 319 PHE A CA  1 
ATOM   1238  C C   . PHE A 1 320 ? 108.812 62.798  149.963 1.00 230.17 ? 319 PHE A C   1 
ATOM   1239  O O   . PHE A 1 320 ? 109.779 63.452  149.556 1.00 199.33 ? 319 PHE A O   1 
ATOM   1240  C CB  . PHE A 1 320 ? 107.573 60.994  148.677 1.00 162.18 ? 319 PHE A CB  1 
ATOM   1241  C CG  . PHE A 1 320 ? 106.480 60.518  147.742 1.00 137.05 ? 319 PHE A CG  1 
ATOM   1242  C CD1 . PHE A 1 320 ? 105.164 60.314  148.155 1.00 183.52 ? 319 PHE A CD1 1 
ATOM   1243  C CD2 . PHE A 1 320 ? 106.791 60.227  146.436 1.00 112.78 ? 319 PHE A CD2 1 
ATOM   1244  C CE1 . PHE A 1 320 ? 104.198 59.852  147.268 1.00 173.85 ? 319 PHE A CE1 1 
ATOM   1245  C CE2 . PHE A 1 320 ? 105.832 59.774  145.542 1.00 145.66 ? 319 PHE A CE2 1 
ATOM   1246  C CZ  . PHE A 1 320 ? 104.530 59.596  145.954 1.00 169.07 ? 319 PHE A CZ  1 
ATOM   1247  N N   . SER A 1 321 ? 108.780 62.316  151.213 1.00 263.70 ? 320 SER A N   1 
ATOM   1248  C CA  . SER A 1 321 ? 109.782 62.657  152.218 1.00 276.70 ? 320 SER A CA  1 
ATOM   1249  C C   . SER A 1 321 ? 111.036 61.769  152.147 1.00 288.43 ? 320 SER A C   1 
ATOM   1250  O O   . SER A 1 321 ? 112.021 62.071  152.817 1.00 261.64 ? 320 SER A O   1 
ATOM   1251  C CB  . SER A 1 321 ? 109.153 62.596  153.596 1.00 295.28 ? 320 SER A CB  1 
ATOM   1252  O OG  . SER A 1 321 ? 110.042 63.082  154.592 1.00 338.48 ? 320 SER A OG  1 
ATOM   1253  N N   . THR A 1 322 ? 111.021 60.678  151.351 1.00 291.43 ? 321 THR A N   1 
ATOM   1254  C CA  . THR A 1 322 ? 111.896 59.525  151.551 1.00 294.33 ? 321 THR A CA  1 
ATOM   1255  C C   . THR A 1 322 ? 112.323 58.907  150.216 1.00 275.53 ? 321 THR A C   1 
ATOM   1256  O O   . THR A 1 322 ? 111.594 59.001  149.231 1.00 261.08 ? 321 THR A O   1 
ATOM   1257  C CB  . THR A 1 322 ? 111.186 58.470  152.418 1.00 324.18 ? 321 THR A CB  1 
ATOM   1258  O OG1 . THR A 1 322 ? 110.680 59.082  153.606 1.00 379.76 ? 321 THR A OG1 1 
ATOM   1259  C CG2 . THR A 1 322 ? 112.068 57.314  152.847 1.00 376.51 ? 321 THR A CG2 1 
ATOM   1260  N N   . GLN A 1 323 ? 113.512 58.267  150.212 1.00 304.54 ? 322 GLN A N   1 
ATOM   1261  C CA  . GLN A 1 323 ? 114.048 57.397  149.152 1.00 311.28 ? 322 GLN A CA  1 
ATOM   1262  C C   . GLN A 1 323 ? 113.932 58.038  147.760 1.00 258.98 ? 322 GLN A C   1 
ATOM   1263  O O   . GLN A 1 323 ? 113.498 57.402  146.787 1.00 218.95 ? 322 GLN A O   1 
ATOM   1264  C CB  . GLN A 1 323 ? 113.451 55.979  149.239 1.00 339.40 ? 322 GLN A CB  1 
ATOM   1265  C CG  . GLN A 1 323 ? 111.936 55.824  149.059 1.00 360.44 ? 322 GLN A CG  1 
ATOM   1266  C CD  . GLN A 1 323 ? 111.472 54.384  149.027 1.00 401.35 ? 322 GLN A CD  1 
ATOM   1267  O OE1 . GLN A 1 323 ? 112.165 53.488  148.546 1.00 438.69 ? 322 GLN A OE1 1 
ATOM   1268  N NE2 . GLN A 1 323 ? 110.278 54.141  149.544 1.00 408.21 ? 322 GLN A NE2 1 
ATOM   1269  N N   . VAL A 1 324 ? 114.369 59.305  147.687 1.00 212.13 ? 323 VAL A N   1 
ATOM   1270  C CA  . VAL A 1 324 ? 114.130 60.195  146.554 1.00 239.61 ? 323 VAL A CA  1 
ATOM   1271  C C   . VAL A 1 324 ? 114.624 59.610  145.221 1.00 210.61 ? 323 VAL A C   1 
ATOM   1272  O O   . VAL A 1 324 ? 114.026 59.899  144.175 1.00 203.82 ? 323 VAL A O   1 
ATOM   1273  C CB  . VAL A 1 324 ? 114.755 61.581  146.838 1.00 277.91 ? 323 VAL A CB  1 
ATOM   1274  C CG1 . VAL A 1 324 ? 116.275 61.556  146.902 1.00 283.75 ? 323 VAL A CG1 1 
ATOM   1275  C CG2 . VAL A 1 324 ? 114.302 62.632  145.834 1.00 348.60 ? 323 VAL A CG2 1 
ATOM   1276  N N   . ASP A 1 325 ? 115.708 58.809  145.255 1.00 204.10 ? 324 ASP A N   1 
ATOM   1277  C CA  . ASP A 1 325 ? 116.291 58.226  144.052 1.00 249.06 ? 324 ASP A CA  1 
ATOM   1278  C C   . ASP A 1 325 ? 115.329 57.242  143.370 1.00 252.71 ? 324 ASP A C   1 
ATOM   1279  O O   . ASP A 1 325 ? 115.379 57.123  142.141 1.00 272.40 ? 324 ASP A O   1 
ATOM   1280  C CB  . ASP A 1 325 ? 117.661 57.591  144.335 1.00 297.53 ? 324 ASP A CB  1 
ATOM   1281  C CG  . ASP A 1 325 ? 117.706 56.540  145.436 1.00 370.90 ? 324 ASP A CG  1 
ATOM   1282  O OD1 . ASP A 1 325 ? 116.701 56.387  146.160 1.00 376.48 ? 324 ASP A OD1 1 
ATOM   1283  O OD2 . ASP A 1 325 ? 118.756 55.880  145.561 1.00 425.22 ? 324 ASP A OD2 1 
ATOM   1284  N N   . THR A 1 326 ? 114.473 56.543  144.143 1.00 218.80 ? 325 THR A N   1 
ATOM   1285  C CA  . THR A 1 326 ? 113.420 55.710  143.570 1.00 235.11 ? 325 THR A CA  1 
ATOM   1286  C C   . THR A 1 326 ? 112.385 56.590  142.870 1.00 221.68 ? 325 THR A C   1 
ATOM   1287  O O   . THR A 1 326 ? 111.893 56.210  141.815 1.00 242.29 ? 325 THR A O   1 
ATOM   1288  C CB  . THR A 1 326 ? 112.738 54.796  144.600 1.00 295.05 ? 325 THR A CB  1 
ATOM   1289  O OG1 . THR A 1 326 ? 111.992 55.568  145.539 1.00 264.57 ? 325 THR A OG1 1 
ATOM   1290  C CG2 . THR A 1 326 ? 113.717 53.917  145.350 1.00 357.67 ? 325 THR A CG2 1 
ATOM   1291  N N   . VAL A 1 327 ? 112.072 57.759  143.456 1.00 172.64 ? 326 VAL A N   1 
ATOM   1292  C CA  . VAL A 1 327 ? 111.116 58.704  142.880 1.00 133.43 ? 326 VAL A CA  1 
ATOM   1293  C C   . VAL A 1 327 ? 111.672 59.302  141.582 1.00 126.43 ? 326 VAL A C   1 
ATOM   1294  O O   . VAL A 1 327 ? 111.003 59.256  140.542 1.00 154.31 ? 326 VAL A O   1 
ATOM   1295  C CB  . VAL A 1 327 ? 110.704 59.794  143.870 1.00 122.67 ? 326 VAL A CB  1 
ATOM   1296  C CG1 . VAL A 1 327 ? 109.505 60.526  143.319 1.00 186.16 ? 326 VAL A CG1 1 
ATOM   1297  C CG2 . VAL A 1 327 ? 110.348 59.222  145.229 1.00 157.99 ? 326 VAL A CG2 1 
ATOM   1298  N N   . ALA A 1 328 ? 112.899 59.817  141.619 1.00 107.05 ? 327 ALA A N   1 
ATOM   1299  C CA  . ALA A 1 328 ? 113.595 60.160  140.379 1.00 162.27 ? 327 ALA A CA  1 
ATOM   1300  C C   . ALA A 1 328 ? 113.645 59.029  139.321 1.00 148.17 ? 327 ALA A C   1 
ATOM   1301  O O   . ALA A 1 328 ? 113.514 59.277  138.124 1.00 169.80 ? 327 ALA A O   1 
ATOM   1302  C CB  . ALA A 1 328 ? 114.987 60.588  140.714 1.00 182.47 ? 327 ALA A CB  1 
ATOM   1303  N N   . THR A 1 329 ? 113.844 57.777  139.744 1.00 161.05 ? 328 THR A N   1 
ATOM   1304  C CA  . THR A 1 329 ? 113.822 56.641  138.839 1.00 186.35 ? 328 THR A CA  1 
ATOM   1305  C C   . THR A 1 329 ? 112.440 56.506  138.190 1.00 164.09 ? 328 THR A C   1 
ATOM   1306  O O   . THR A 1 329 ? 112.384 56.236  136.988 1.00 179.91 ? 328 THR A O   1 
ATOM   1307  C CB  . THR A 1 329 ? 114.273 55.361  139.561 1.00 250.72 ? 328 THR A CB  1 
ATOM   1308  O OG1 . THR A 1 329 ? 115.616 55.591  139.996 1.00 196.70 ? 328 THR A OG1 1 
ATOM   1309  C CG2 . THR A 1 329 ? 114.212 54.104  138.717 1.00 315.36 ? 328 THR A CG2 1 
ATOM   1310  N N   . LYS A 1 330 ? 111.343 56.681  138.957 1.00 136.43 ? 329 LYS A N   1 
ATOM   1311  C CA  . LYS A 1 330 ? 110.003 56.663  138.388 1.00 164.53 ? 329 LYS A CA  1 
ATOM   1312  C C   . LYS A 1 330 ? 109.944 57.665  137.243 1.00 128.93 ? 329 LYS A C   1 
ATOM   1313  O O   . LYS A 1 330 ? 109.471 57.334  136.161 1.00 155.68 ? 329 LYS A O   1 
ATOM   1314  C CB  . LYS A 1 330 ? 108.881 56.963  139.404 1.00 167.27 ? 329 LYS A CB  1 
ATOM   1315  C CG  . LYS A 1 330 ? 108.659 55.863  140.442 1.00 190.80 ? 329 LYS A CG  1 
ATOM   1316  C CD  . LYS A 1 330 ? 107.541 56.188  141.397 1.00 243.12 ? 329 LYS A CD  1 
ATOM   1317  C CE  . LYS A 1 330 ? 107.385 55.191  142.521 1.00 297.14 ? 329 LYS A CE  1 
ATOM   1318  N NZ  . LYS A 1 330 ? 106.564 54.032  142.110 1.00 296.25 ? 329 LYS A NZ  1 
ATOM   1319  N N   . VAL A 1 331 ? 110.405 58.888  137.486 1.00 100.98 ? 330 VAL A N   1 
ATOM   1320  C CA  . VAL A 1 331 ? 110.333 59.944  136.482 1.00 134.43 ? 330 VAL A CA  1 
ATOM   1321  C C   . VAL A 1 331 ? 111.177 59.588  135.261 1.00 118.69 ? 330 VAL A C   1 
ATOM   1322  O O   . VAL A 1 331 ? 110.722 59.743  134.136 1.00 90.46  ? 330 VAL A O   1 
ATOM   1323  C CB  . VAL A 1 331 ? 110.718 61.321  137.071 1.00 132.95 ? 330 VAL A CB  1 
ATOM   1324  C CG1 . VAL A 1 331 ? 110.838 62.422  136.029 1.00 98.12  ? 330 VAL A CG1 1 
ATOM   1325  C CG2 . VAL A 1 331 ? 109.720 61.748  138.151 1.00 123.66 ? 330 VAL A CG2 1 
ATOM   1326  N N   . LYS A 1 332 ? 112.388 59.102  135.487 1.00 139.05 ? 331 LYS A N   1 
ATOM   1327  C CA  . LYS A 1 332 ? 113.290 58.797  134.398 1.00 151.15 ? 331 LYS A CA  1 
ATOM   1328  C C   . LYS A 1 332 ? 112.621 57.848  133.402 1.00 171.94 ? 331 LYS A C   1 
ATOM   1329  O O   . LYS A 1 332 ? 112.835 57.998  132.191 1.00 174.79 ? 331 LYS A O   1 
ATOM   1330  C CB  . LYS A 1 332 ? 114.565 58.193  135.003 1.00 241.37 ? 331 LYS A CB  1 
ATOM   1331  C CG  . LYS A 1 332 ? 115.584 57.644  134.006 1.00 257.04 ? 331 LYS A CG  1 
ATOM   1332  C CD  . LYS A 1 332 ? 116.833 57.151  134.690 1.00 286.20 ? 331 LYS A CD  1 
ATOM   1333  C CE  . LYS A 1 332 ? 117.961 56.831  133.734 1.00 326.30 ? 331 LYS A CE  1 
ATOM   1334  N NZ  . LYS A 1 332 ? 119.270 56.886  134.430 1.00 373.20 ? 331 LYS A NZ  1 
ATOM   1335  N N   . ASP A 1 333 ? 111.853 56.860  133.920 1.00 165.49 ? 332 ASP A N   1 
ATOM   1336  C CA  . ASP A 1 333 ? 111.091 55.917  133.111 1.00 185.90 ? 332 ASP A CA  1 
ATOM   1337  C C   . ASP A 1 333 ? 109.887 56.610  132.482 1.00 146.49 ? 332 ASP A C   1 
ATOM   1338  O O   . ASP A 1 333 ? 109.581 56.361  131.320 1.00 130.66 ? 332 ASP A O   1 
ATOM   1339  C CB  . ASP A 1 333 ? 110.681 54.693  133.936 1.00 184.32 ? 332 ASP A CB  1 
ATOM   1340  C CG  . ASP A 1 333 ? 111.835 53.788  134.364 1.00 287.96 ? 332 ASP A CG  1 
ATOM   1341  O OD1 . ASP A 1 333 ? 112.983 53.989  133.889 1.00 309.90 ? 332 ASP A OD1 1 
ATOM   1342  O OD2 . ASP A 1 333 ? 111.583 52.878  135.178 1.00 353.97 ? 332 ASP A OD2 1 
ATOM   1343  N N   . ALA A 1 334 ? 109.215 57.472  133.249 1.00 124.81 ? 333 ALA A N   1 
ATOM   1344  C CA  . ALA A 1 334 ? 107.960 58.091  132.838 1.00 133.79 ? 333 ALA A CA  1 
ATOM   1345  C C   . ALA A 1 334 ? 108.146 58.958  131.613 1.00 96.89  ? 333 ALA A C   1 
ATOM   1346  O O   . ALA A 1 334 ? 107.284 58.944  130.721 1.00 114.04 ? 333 ALA A O   1 
ATOM   1347  C CB  . ALA A 1 334 ? 107.361 58.922  133.952 1.00 143.33 ? 333 ALA A CB  1 
ATOM   1348  N N   . LEU A 1 335 ? 109.257 59.702  131.572 1.00 92.41  ? 334 LEU A N   1 
ATOM   1349  C CA  . LEU A 1 335 ? 109.425 60.692  130.513 1.00 106.10 ? 334 LEU A CA  1 
ATOM   1350  C C   . LEU A 1 335 ? 109.470 59.958  129.171 1.00 145.61 ? 334 LEU A C   1 
ATOM   1351  O O   . LEU A 1 335 ? 108.891 60.422  128.184 1.00 81.38  ? 334 LEU A O   1 
ATOM   1352  C CB  . LEU A 1 335 ? 110.697 61.503  130.699 1.00 92.12  ? 334 LEU A CB  1 
ATOM   1353  C CG  . LEU A 1 335 ? 110.779 62.290  131.980 1.00 117.81 ? 334 LEU A CG  1 
ATOM   1354  C CD1 . LEU A 1 335 ? 112.248 62.635  132.366 1.00 161.67 ? 334 LEU A CD1 1 
ATOM   1355  C CD2 . LEU A 1 335 ? 109.923 63.509  131.814 1.00 109.61 ? 334 LEU A CD2 1 
ATOM   1356  N N   . GLU A 1 336 ? 110.160 58.802  129.136 1.00 136.05 ? 335 GLU A N   1 
ATOM   1357  C CA  . GLU A 1 336 ? 110.319 58.012  127.931 1.00 149.51 ? 335 GLU A CA  1 
ATOM   1358  C C   . GLU A 1 336 ? 108.951 57.541  127.453 1.00 133.91 ? 335 GLU A C   1 
ATOM   1359  O O   . GLU A 1 336 ? 108.644 57.628  126.254 1.00 162.69 ? 335 GLU A O   1 
ATOM   1360  C CB  . GLU A 1 336 ? 111.294 56.875  128.222 1.00 177.31 ? 335 GLU A CB  1 
ATOM   1361  C CG  . GLU A 1 336 ? 111.551 55.975  127.028 1.00 281.06 ? 335 GLU A CG  1 
ATOM   1362  C CD  . GLU A 1 336 ? 112.589 54.885  127.241 1.00 369.24 ? 335 GLU A CD  1 
ATOM   1363  O OE1 . GLU A 1 336 ? 113.227 54.857  128.316 1.00 422.05 ? 335 GLU A OE1 1 
ATOM   1364  O OE2 . GLU A 1 336 ? 112.756 54.059  126.326 1.00 449.05 ? 335 GLU A OE2 1 
ATOM   1365  N N   . PHE A 1 337 ? 108.148 57.011  128.380 1.00 108.25 ? 336 PHE A N   1 
ATOM   1366  C CA  . PHE A 1 337 ? 106.846 56.478  128.017 1.00 139.10 ? 336 PHE A CA  1 
ATOM   1367  C C   . PHE A 1 337 ? 105.973 57.561  127.391 1.00 114.02 ? 336 PHE A C   1 
ATOM   1368  O O   . PHE A 1 337 ? 105.383 57.371  126.324 1.00 133.99 ? 336 PHE A O   1 
ATOM   1369  C CB  . PHE A 1 337 ? 106.132 55.849  129.212 1.00 124.35 ? 336 PHE A CB  1 
ATOM   1370  C CG  . PHE A 1 337 ? 104.711 55.433  128.917 1.00 139.74 ? 336 PHE A CG  1 
ATOM   1371  C CD1 . PHE A 1 337 ? 104.418 54.223  128.293 1.00 194.73 ? 336 PHE A CD1 1 
ATOM   1372  C CD2 . PHE A 1 337 ? 103.656 56.270  129.259 1.00 128.98 ? 336 PHE A CD2 1 
ATOM   1373  C CE1 . PHE A 1 337 ? 103.096 53.881  128.032 1.00 243.63 ? 336 PHE A CE1 1 
ATOM   1374  C CE2 . PHE A 1 337 ? 102.342 55.937  129.001 1.00 149.72 ? 336 PHE A CE2 1 
ATOM   1375  C CZ  . PHE A 1 337 ? 102.064 54.735  128.394 1.00 236.30 ? 336 PHE A CZ  1 
ATOM   1376  N N   . TRP A 1 338 ? 105.874 58.689  128.073 1.00 103.48 ? 337 TRP A N   1 
ATOM   1377  C CA  . TRP A 1 338 ? 104.911 59.680  127.647 1.00 93.33  ? 337 TRP A CA  1 
ATOM   1378  C C   . TRP A 1 338 ? 105.406 60.367  126.389 1.00 121.12 ? 337 TRP A C   1 
ATOM   1379  O O   . TRP A 1 338 ? 104.561 60.801  125.611 1.00 136.16 ? 337 TRP A O   1 
ATOM   1380  C CB  . TRP A 1 338 ? 104.642 60.670  128.765 1.00 78.75  ? 337 TRP A CB  1 
ATOM   1381  C CG  . TRP A 1 338 ? 103.827 60.092  129.866 1.00 79.95  ? 337 TRP A CG  1 
ATOM   1382  C CD1 . TRP A 1 338 ? 104.174 59.729  131.149 1.00 79.58  ? 337 TRP A CD1 1 
ATOM   1383  C CD2 . TRP A 1 338 ? 102.427 59.839  129.733 1.00 81.66  ? 337 TRP A CD2 1 
ATOM   1384  N NE1 . TRP A 1 338 ? 103.066 59.254  131.820 1.00 75.02  ? 337 TRP A NE1 1 
ATOM   1385  C CE2 . TRP A 1 338 ? 101.985 59.315  130.973 1.00 76.42  ? 337 TRP A CE2 1 
ATOM   1386  C CE3 . TRP A 1 338 ? 101.529 60.013  128.700 1.00 87.73  ? 337 TRP A CE3 1 
ATOM   1387  C CZ2 . TRP A 1 338 ? 100.674 58.962  131.188 1.00 86.88  ? 337 TRP A CZ2 1 
ATOM   1388  C CZ3 . TRP A 1 338 ? 100.219 59.677  128.923 1.00 121.51 ? 337 TRP A CZ3 1 
ATOM   1389  C CH2 . TRP A 1 338 ? 99.801  59.156  130.140 1.00 143.23 ? 337 TRP A CH2 1 
ATOM   1390  N N   . LEU A 1 339 ? 106.738 60.470  126.175 1.00 80.97  ? 338 LEU A N   1 
ATOM   1391  C CA  . LEU A 1 339 ? 107.212 60.967  124.890 1.00 124.09 ? 338 LEU A CA  1 
ATOM   1392  C C   . LEU A 1 339 ? 106.777 60.035  123.762 1.00 152.02 ? 338 LEU A C   1 
ATOM   1393  O O   . LEU A 1 339 ? 106.308 60.517  122.722 1.00 131.15 ? 338 LEU A O   1 
ATOM   1394  C CB  . LEU A 1 339 ? 108.721 61.107  124.981 1.00 120.94 ? 338 LEU A CB  1 
ATOM   1395  C CG  . LEU A 1 339 ? 109.195 62.350  125.716 1.00 128.07 ? 338 LEU A CG  1 
ATOM   1396  C CD1 . LEU A 1 339 ? 110.669 62.269  126.078 1.00 146.73 ? 338 LEU A CD1 1 
ATOM   1397  C CD2 . LEU A 1 339 ? 108.942 63.586  124.875 1.00 120.00 ? 338 LEU A CD2 1 
ATOM   1398  N N   . GLN A 1 340 ? 106.914 58.715  123.989 1.00 142.46 ? 339 GLN A N   1 
ATOM   1399  C CA  . GLN A 1 340 ? 106.453 57.717  123.029 1.00 168.30 ? 339 GLN A CA  1 
ATOM   1400  C C   . GLN A 1 340 ? 104.948 57.846  122.766 1.00 174.53 ? 339 GLN A C   1 
ATOM   1401  O O   . GLN A 1 340 ? 104.506 57.574  121.642 1.00 218.59 ? 339 GLN A O   1 
ATOM   1402  C CB  . GLN A 1 340 ? 106.815 56.297  123.500 1.00 188.65 ? 339 GLN A CB  1 
ATOM   1403  C CG  . GLN A 1 340 ? 108.290 55.929  123.388 1.00 220.85 ? 339 GLN A CG  1 
ATOM   1404  C CD  . GLN A 1 340 ? 108.835 55.836  121.981 1.00 291.66 ? 339 GLN A CD  1 
ATOM   1405  O OE1 . GLN A 1 340 ? 110.018 56.081  121.743 1.00 319.20 ? 339 GLN A OE1 1 
ATOM   1406  N NE2 . GLN A 1 340 ? 107.973 55.496  121.032 1.00 341.61 ? 339 GLN A NE2 1 
ATOM   1407  N N   . ALA A 1 341 ? 104.174 58.240  123.792 1.00 164.52 ? 340 ALA A N   1 
ATOM   1408  C CA  . ALA A 1 341 ? 102.742 58.494  123.674 1.00 156.18 ? 340 ALA A CA  1 
ATOM   1409  C C   . ALA A 1 341 ? 102.434 59.781  122.895 1.00 118.95 ? 340 ALA A C   1 
ATOM   1410  O O   . ALA A 1 341 ? 101.349 59.875  122.325 1.00 129.72 ? 340 ALA A O   1 
ATOM   1411  C CB  . ALA A 1 341 ? 102.130 58.532  125.057 1.00 219.18 ? 340 ALA A CB  1 
ATOM   1412  N N   . GLY A 1 342 ? 103.347 60.770  122.879 1.00 124.91 ? 341 GLY A N   1 
ATOM   1413  C CA  . GLY A 1 342 ? 103.290 61.901  121.955 1.00 160.27 ? 341 GLY A CA  1 
ATOM   1414  C C   . GLY A 1 342 ? 103.105 63.283  122.592 1.00 141.64 ? 341 GLY A C   1 
ATOM   1415  O O   . GLY A 1 342 ? 102.811 64.248  121.869 1.00 156.29 ? 341 GLY A O   1 
ATOM   1416  N N   . VAL A 1 343 ? 103.283 63.381  123.921 1.00 92.53  ? 342 VAL A N   1 
ATOM   1417  C CA  . VAL A 1 343 ? 103.209 64.659  124.615 1.00 89.30  ? 342 VAL A CA  1 
ATOM   1418  C C   . VAL A 1 343 ? 104.380 65.547  124.218 1.00 94.09  ? 342 VAL A C   1 
ATOM   1419  O O   . VAL A 1 343 ? 105.415 64.995  123.918 1.00 115.73 ? 342 VAL A O   1 
ATOM   1420  C CB  . VAL A 1 343 ? 103.235 64.464  126.135 1.00 86.88  ? 342 VAL A CB  1 
ATOM   1421  C CG1 . VAL A 1 343 ? 102.212 63.460  126.603 1.00 102.60 ? 342 VAL A CG1 1 
ATOM   1422  C CG2 . VAL A 1 343 ? 104.618 64.075  126.607 1.00 81.12  ? 342 VAL A CG2 1 
ATOM   1423  N N   . ASP A 1 344 ? 104.221 66.882  124.276 1.00 87.74  ? 343 ASP A N   1 
ATOM   1424  C CA  . ASP A 1 344 ? 105.233 67.810  123.809 1.00 108.79 ? 343 ASP A CA  1 
ATOM   1425  C C   . ASP A 1 344 ? 106.220 68.246  124.895 1.00 86.82  ? 343 ASP A C   1 
ATOM   1426  O O   . ASP A 1 344 ? 107.157 68.974  124.571 1.00 119.24 ? 343 ASP A O   1 
ATOM   1427  C CB  . ASP A 1 344 ? 104.578 69.014  123.157 1.00 154.56 ? 343 ASP A CB  1 
ATOM   1428  C CG  . ASP A 1 344 ? 103.684 68.582  122.004 1.00 213.76 ? 343 ASP A CG  1 
ATOM   1429  O OD1 . ASP A 1 344 ? 104.217 68.058  120.984 1.00 272.80 ? 343 ASP A OD1 1 
ATOM   1430  O OD2 . ASP A 1 344 ? 102.468 68.774  122.132 1.00 226.94 ? 343 ASP A OD2 1 
ATOM   1431  N N   . GLY A 1 345 ? 106.071 67.765  126.124 1.00 64.38  ? 344 GLY A N   1 
ATOM   1432  C CA  . GLY A 1 345 ? 107.018 68.115  127.156 1.00 67.62  ? 344 GLY A CA  1 
ATOM   1433  C C   . GLY A 1 345 ? 106.458 67.859  128.544 1.00 65.84  ? 344 GLY A C   1 
ATOM   1434  O O   . GLY A 1 345 ? 105.407 67.293  128.664 1.00 65.96  ? 344 GLY A O   1 
ATOM   1435  N N   . PHE A 1 346 ? 107.165 68.300  129.573 1.00 65.95  ? 345 PHE A N   1 
ATOM   1436  C CA  . PHE A 1 346 ? 106.814 68.022  130.941 1.00 65.50  ? 345 PHE A CA  1 
ATOM   1437  C C   . PHE A 1 346 ? 107.006 69.214  131.870 1.00 66.71  ? 345 PHE A C   1 
ATOM   1438  O O   . PHE A 1 346 ? 107.915 70.013  131.769 1.00 118.08 ? 345 PHE A O   1 
ATOM   1439  C CB  . PHE A 1 346 ? 107.727 66.899  131.410 1.00 83.90  ? 345 PHE A CB  1 
ATOM   1440  C CG  . PHE A 1 346 ? 107.493 65.699  130.549 1.00 77.78  ? 345 PHE A CG  1 
ATOM   1441  C CD1 . PHE A 1 346 ? 106.376 64.893  130.676 1.00 99.54  ? 345 PHE A CD1 1 
ATOM   1442  C CD2 . PHE A 1 346 ? 108.373 65.405  129.598 1.00 74.94  ? 345 PHE A CD2 1 
ATOM   1443  C CE1 . PHE A 1 346 ? 106.184 63.808  129.860 1.00 99.84  ? 345 PHE A CE1 1 
ATOM   1444  C CE2 . PHE A 1 346 ? 108.179 64.313  128.785 1.00 118.71 ? 345 PHE A CE2 1 
ATOM   1445  C CZ  . PHE A 1 346 ? 107.080 63.529  128.903 1.00 129.79 ? 345 PHE A CZ  1 
ATOM   1446  N N   . GLN A 1 347 ? 106.117 69.342  132.815 1.00 67.98  ? 346 GLN A N   1 
ATOM   1447  C CA  . GLN A 1 347 ? 106.266 70.300  133.884 1.00 62.55  ? 346 GLN A CA  1 
ATOM   1448  C C   . GLN A 1 347 ? 106.629 69.423  135.068 1.00 57.85  ? 346 GLN A C   1 
ATOM   1449  O O   . GLN A 1 347 ? 106.042 68.368  135.263 1.00 67.26  ? 346 GLN A O   1 
ATOM   1450  C CB  . GLN A 1 347 ? 104.986 71.181  134.040 1.00 53.37  ? 346 GLN A CB  1 
ATOM   1451  C CG  . GLN A 1 347 ? 104.968 71.919  135.340 1.00 63.50  ? 346 GLN A CG  1 
ATOM   1452  C CD  . GLN A 1 347 ? 103.915 72.974  135.470 1.00 86.58  ? 346 GLN A CD  1 
ATOM   1453  O OE1 . GLN A 1 347 ? 104.155 74.154  135.161 1.00 96.01  ? 346 GLN A OE1 1 
ATOM   1454  N NE2 . GLN A 1 347 ? 102.744 72.557  135.975 1.00 99.65  ? 346 GLN A NE2 1 
ATOM   1455  N N   . VAL A 1 348 ? 107.544 69.905  135.904 1.00 77.13  ? 347 VAL A N   1 
ATOM   1456  C CA  . VAL A 1 348 ? 107.686 69.400  137.279 1.00 68.31  ? 347 VAL A CA  1 
ATOM   1457  C C   . VAL A 1 348 ? 107.713 70.589  138.227 1.00 67.91  ? 347 VAL A C   1 
ATOM   1458  O O   . VAL A 1 348 ? 108.187 71.673  137.882 1.00 69.27  ? 347 VAL A O   1 
ATOM   1459  C CB  . VAL A 1 348 ? 108.956 68.574  137.379 1.00 68.32  ? 347 VAL A CB  1 
ATOM   1460  C CG1 . VAL A 1 348 ? 108.841 67.350  136.473 1.00 86.86  ? 347 VAL A CG1 1 
ATOM   1461  C CG2 . VAL A 1 348 ? 110.206 69.396  137.024 1.00 76.36  ? 347 VAL A CG2 1 
ATOM   1462  N N   . ARG A 1 349 ? 107.191 70.378  139.420 1.00 75.07  ? 348 ARG A N   1 
ATOM   1463  C CA  . ARG A 1 349 ? 107.018 71.426  140.412 1.00 92.29  ? 348 ARG A CA  1 
ATOM   1464  C C   . ARG A 1 349 ? 107.696 71.150  141.756 1.00 77.13  ? 348 ARG A C   1 
ATOM   1465  O O   . ARG A 1 349 ? 108.222 70.074  142.014 1.00 103.89 ? 348 ARG A O   1 
ATOM   1466  C CB  . ARG A 1 349 ? 105.534 71.560  140.612 1.00 73.76  ? 348 ARG A CB  1 
ATOM   1467  C CG  . ARG A 1 349 ? 104.931 72.217  139.413 1.00 85.59  ? 348 ARG A CG  1 
ATOM   1468  C CD  . ARG A 1 349 ? 103.551 72.735  139.771 1.00 112.45 ? 348 ARG A CD  1 
ATOM   1469  N NE  . ARG A 1 349 ? 102.638 71.656  139.521 1.00 108.99 ? 348 ARG A NE  1 
ATOM   1470  C CZ  . ARG A 1 349 ? 101.858 71.066  140.411 1.00 118.59 ? 348 ARG A CZ  1 
ATOM   1471  N NH1 . ARG A 1 349 ? 100.996 70.194  139.946 1.00 185.89 ? 348 ARG A NH1 1 
ATOM   1472  N NH2 . ARG A 1 349 ? 101.888 71.324  141.709 1.00 134.32 ? 348 ARG A NH2 1 
ATOM   1473  N N   . ASP A 1 350 ? 107.693 72.184  142.550 1.00 67.97  ? 349 ASP A N   1 
ATOM   1474  C CA  . ASP A 1 350 ? 108.212 72.127  143.880 1.00 108.50 ? 349 ASP A CA  1 
ATOM   1475  C C   . ASP A 1 350 ? 109.684 71.669  143.948 1.00 98.35  ? 349 ASP A C   1 
ATOM   1476  O O   . ASP A 1 350 ? 110.061 71.069  144.934 1.00 145.64 ? 349 ASP A O   1 
ATOM   1477  C CB  . ASP A 1 350 ? 107.205 71.303  144.679 1.00 117.55 ? 349 ASP A CB  1 
ATOM   1478  C CG  . ASP A 1 350 ? 105.776 71.808  144.729 1.00 152.05 ? 349 ASP A CG  1 
ATOM   1479  O OD1 . ASP A 1 350 ? 105.502 72.968  144.344 1.00 193.40 ? 349 ASP A OD1 1 
ATOM   1480  O OD2 . ASP A 1 350 ? 104.924 71.011  145.193 1.00 184.90 ? 349 ASP A OD2 1 
ATOM   1481  N N   . ILE A 1 351 ? 110.537 71.970  142.988 1.00 60.88  ? 350 ILE A N   1 
ATOM   1482  C CA  . ILE A 1 351 ? 111.865 71.426  142.992 1.00 74.56  ? 350 ILE A CA  1 
ATOM   1483  C C   . ILE A 1 351 ? 112.728 71.891  144.190 1.00 126.16 ? 350 ILE A C   1 
ATOM   1484  O O   . ILE A 1 351 ? 113.827 71.354  144.385 1.00 188.06 ? 350 ILE A O   1 
ATOM   1485  C CB  . ILE A 1 351 ? 112.568 71.736  141.658 1.00 85.76  ? 350 ILE A CB  1 
ATOM   1486  C CG1 . ILE A 1 351 ? 112.730 73.248  141.495 1.00 90.30  ? 350 ILE A CG1 1 
ATOM   1487  C CG2 . ILE A 1 351 ? 111.862 71.043  140.509 1.00 78.76  ? 350 ILE A CG2 1 
ATOM   1488  C CD1 . ILE A 1 351 ? 113.565 73.653  140.377 1.00 139.87 ? 350 ILE A CD1 1 
ATOM   1489  N N   . GLU A 1 352 ? 112.314 72.857  145.014 1.00 105.99 ? 351 GLU A N   1 
ATOM   1490  C CA  . GLU A 1 352 ? 112.980 73.073  146.288 1.00 158.00 ? 351 GLU A CA  1 
ATOM   1491  C C   . GLU A 1 352 ? 112.759 71.911  147.273 1.00 168.77 ? 351 GLU A C   1 
ATOM   1492  O O   . GLU A 1 352 ? 113.553 71.774  148.219 1.00 221.79 ? 351 GLU A O   1 
ATOM   1493  C CB  . GLU A 1 352 ? 112.512 74.389  146.920 1.00 229.86 ? 351 GLU A CB  1 
ATOM   1494  C CG  . GLU A 1 352 ? 111.033 74.428  147.372 1.00 247.79 ? 351 GLU A CG  1 
ATOM   1495  C CD  . GLU A 1 352 ? 109.979 74.500  146.275 1.00 203.29 ? 351 GLU A CD  1 
ATOM   1496  O OE1 . GLU A 1 352 ? 110.358 74.840  145.120 1.00 244.86 ? 351 GLU A OE1 1 
ATOM   1497  O OE2 . GLU A 1 352 ? 108.778 74.233  146.577 1.00 143.75 ? 351 GLU A OE2 1 
ATOM   1498  N N   . ASN A 1 353 ? 111.692 71.100  147.089 1.00 107.15 ? 352 ASN A N   1 
ATOM   1499  C CA  . ASN A 1 353 ? 111.445 69.916  147.901 1.00 125.11 ? 352 ASN A CA  1 
ATOM   1500  C C   . ASN A 1 353 ? 112.100 68.649  147.326 1.00 135.80 ? 352 ASN A C   1 
ATOM   1501  O O   . ASN A 1 353 ? 111.913 67.554  147.872 1.00 172.66 ? 352 ASN A O   1 
ATOM   1502  C CB  . ASN A 1 353 ? 109.940 69.687  148.069 1.00 156.34 ? 352 ASN A CB  1 
ATOM   1503  C CG  . ASN A 1 353 ? 109.216 70.550  149.084 1.00 160.20 ? 352 ASN A CG  1 
ATOM   1504  O OD1 . ASN A 1 353 ? 108.008 70.388  149.287 1.00 192.66 ? 352 ASN A OD1 1 
ATOM   1505  N ND2 . ASN A 1 353 ? 109.923 71.446  149.736 1.00 189.82 ? 352 ASN A ND2 1 
ATOM   1506  N N   . LEU A 1 354 ? 112.878 68.781  146.244 1.00 116.99 ? 353 LEU A N   1 
ATOM   1507  C CA  . LEU A 1 354 ? 113.610 67.675  145.658 1.00 132.63 ? 353 LEU A CA  1 
ATOM   1508  C C   . LEU A 1 354 ? 115.094 67.795  146.041 1.00 175.04 ? 353 LEU A C   1 
ATOM   1509  O O   . LEU A 1 354 ? 115.737 68.818  145.787 1.00 169.95 ? 353 LEU A O   1 
ATOM   1510  C CB  . LEU A 1 354 ? 113.370 67.773  144.157 1.00 116.86 ? 353 LEU A CB  1 
ATOM   1511  C CG  . LEU A 1 354 ? 114.077 66.765  143.277 1.00 126.13 ? 353 LEU A CG  1 
ATOM   1512  C CD1 . LEU A 1 354 ? 113.526 65.388  143.513 1.00 162.47 ? 353 LEU A CD1 1 
ATOM   1513  C CD2 . LEU A 1 354 ? 113.940 67.152  141.819 1.00 129.16 ? 353 LEU A CD2 1 
ATOM   1514  N N   . LYS A 1 355 ? 115.655 66.745  146.665 1.00 185.69 ? 354 LYS A N   1 
ATOM   1515  C CA  . LYS A 1 355 ? 117.082 66.719  146.960 1.00 206.38 ? 354 LYS A CA  1 
ATOM   1516  C C   . LYS A 1 355 ? 117.874 66.590  145.652 1.00 193.79 ? 354 LYS A C   1 
ATOM   1517  O O   . LYS A 1 355 ? 117.446 65.877  144.755 1.00 170.57 ? 354 LYS A O   1 
ATOM   1518  C CB  . LYS A 1 355 ? 117.399 65.568  147.921 1.00 273.87 ? 354 LYS A CB  1 
ATOM   1519  C CG  . LYS A 1 355 ? 118.847 65.509  148.393 1.00 360.66 ? 354 LYS A CG  1 
ATOM   1520  C CD  . LYS A 1 355 ? 119.127 64.482  149.487 1.00 388.88 ? 354 LYS A CD  1 
ATOM   1521  C CE  . LYS A 1 355 ? 119.095 63.037  149.023 1.00 415.16 ? 354 LYS A CE  1 
ATOM   1522  N NZ  . LYS A 1 355 ? 120.227 62.673  148.130 1.00 379.76 ? 354 LYS A NZ  1 
ATOM   1523  N N   . ASP A 1 356 ? 119.033 67.270  145.551 1.00 203.71 ? 355 ASP A N   1 
ATOM   1524  C CA  . ASP A 1 356 ? 119.940 67.185  144.401 1.00 227.09 ? 355 ASP A CA  1 
ATOM   1525  C C   . ASP A 1 356 ? 119.229 67.624  143.115 1.00 201.61 ? 355 ASP A C   1 
ATOM   1526  O O   . ASP A 1 356 ? 119.434 67.059  142.041 1.00 135.21 ? 355 ASP A O   1 
ATOM   1527  C CB  . ASP A 1 356 ? 120.559 65.783  144.263 1.00 287.37 ? 355 ASP A CB  1 
ATOM   1528  C CG  . ASP A 1 356 ? 121.806 65.693  143.387 1.00 352.13 ? 355 ASP A CG  1 
ATOM   1529  O OD1 . ASP A 1 356 ? 122.331 66.752  142.972 1.00 395.41 ? 355 ASP A OD1 1 
ATOM   1530  O OD2 . ASP A 1 356 ? 122.253 64.555  143.120 1.00 409.45 ? 355 ASP A OD2 1 
ATOM   1531  N N   . ALA A 1 357 ? 118.408 68.674  143.246 1.00 188.62 ? 356 ALA A N   1 
ATOM   1532  C CA  . ALA A 1 357 ? 117.447 69.088  142.237 1.00 153.58 ? 356 ALA A CA  1 
ATOM   1533  C C   . ALA A 1 357 ? 118.095 69.301  140.877 1.00 134.34 ? 356 ALA A C   1 
ATOM   1534  O O   . ALA A 1 357 ? 117.606 68.762  139.871 1.00 178.92 ? 356 ALA A O   1 
ATOM   1535  C CB  . ALA A 1 357 ? 116.828 70.371  142.692 1.00 165.39 ? 356 ALA A CB  1 
ATOM   1536  N N   . SER A 1 358 ? 119.177 70.105  140.854 1.00 114.99 ? 357 SER A N   1 
ATOM   1537  C CA  . SER A 1 358 ? 119.828 70.491  139.602 1.00 164.62 ? 357 SER A CA  1 
ATOM   1538  C C   . SER A 1 358 ? 120.270 69.260  138.772 1.00 152.92 ? 357 SER A C   1 
ATOM   1539  O O   . SER A 1 358 ? 120.198 69.282  137.533 1.00 172.02 ? 357 SER A O   1 
ATOM   1540  C CB  . SER A 1 358 ? 120.958 71.446  139.869 1.00 176.74 ? 357 SER A CB  1 
ATOM   1541  O OG  . SER A 1 358 ? 121.905 70.856  140.753 1.00 270.63 ? 357 SER A OG  1 
ATOM   1542  N N   . SER A 1 359 ? 120.705 68.191  139.450 1.00 148.93 ? 358 SER A N   1 
ATOM   1543  C CA  . SER A 1 359 ? 121.197 66.997  138.793 1.00 189.45 ? 358 SER A CA  1 
ATOM   1544  C C   . SER A 1 359 ? 120.058 66.221  138.138 1.00 176.72 ? 358 SER A C   1 
ATOM   1545  O O   . SER A 1 359 ? 120.227 65.738  137.014 1.00 171.96 ? 358 SER A O   1 
ATOM   1546  C CB  . SER A 1 359 ? 121.943 66.120  139.765 1.00 236.83 ? 358 SER A CB  1 
ATOM   1547  O OG  . SER A 1 359 ? 122.992 66.842  140.404 1.00 232.74 ? 358 SER A OG  1 
ATOM   1548  N N   . PHE A 1 360 ? 118.922 66.091  138.838 1.00 145.62 ? 359 PHE A N   1 
ATOM   1549  C CA  . PHE A 1 360 ? 117.763 65.407  138.278 1.00 166.10 ? 359 PHE A CA  1 
ATOM   1550  C C   . PHE A 1 360 ? 117.193 66.189  137.105 1.00 136.87 ? 359 PHE A C   1 
ATOM   1551  O O   . PHE A 1 360 ? 116.855 65.562  136.107 1.00 114.28 ? 359 PHE A O   1 
ATOM   1552  C CB  . PHE A 1 360 ? 116.695 65.119  139.335 1.00 143.40 ? 359 PHE A CB  1 
ATOM   1553  C CG  . PHE A 1 360 ? 117.117 64.120  140.382 1.00 143.80 ? 359 PHE A CG  1 
ATOM   1554  C CD1 . PHE A 1 360 ? 117.740 62.931  140.018 1.00 135.72 ? 359 PHE A CD1 1 
ATOM   1555  C CD2 . PHE A 1 360 ? 116.866 64.361  141.739 1.00 209.04 ? 359 PHE A CD2 1 
ATOM   1556  C CE1 . PHE A 1 360 ? 118.132 62.023  140.990 1.00 229.80 ? 359 PHE A CE1 1 
ATOM   1557  C CE2 . PHE A 1 360 ? 117.270 63.454  142.709 1.00 249.34 ? 359 PHE A CE2 1 
ATOM   1558  C CZ  . PHE A 1 360 ? 117.894 62.283  142.331 1.00 281.57 ? 359 PHE A CZ  1 
ATOM   1559  N N   . LEU A 1 361 ? 117.122 67.516  137.209 1.00 126.60 ? 360 LEU A N   1 
ATOM   1560  C CA  . LEU A 1 361 ? 116.681 68.320  136.062 1.00 122.82 ? 360 LEU A CA  1 
ATOM   1561  C C   . LEU A 1 361 ? 117.643 68.123  134.887 1.00 117.50 ? 360 LEU A C   1 
ATOM   1562  O O   . LEU A 1 361 ? 117.187 67.980  133.764 1.00 122.32 ? 360 LEU A O   1 
ATOM   1563  C CB  . LEU A 1 361 ? 116.537 69.813  136.367 1.00 99.92  ? 360 LEU A CB  1 
ATOM   1564  C CG  . LEU A 1 361 ? 115.525 70.205  137.473 1.00 109.49 ? 360 LEU A CG  1 
ATOM   1565  C CD1 . LEU A 1 361 ? 115.502 71.704  137.673 1.00 109.06 ? 360 LEU A CD1 1 
ATOM   1566  C CD2 . LEU A 1 361 ? 114.134 69.736  137.236 1.00 102.23 ? 360 LEU A CD2 1 
ATOM   1567  N N   . ALA A 1 362 ? 118.944 68.057  135.137 1.00 116.60 ? 361 ALA A N   1 
ATOM   1568  C CA  . ALA A 1 362 ? 119.898 67.851  134.058 1.00 158.02 ? 361 ALA A CA  1 
ATOM   1569  C C   . ALA A 1 362 ? 119.702 66.507  133.364 1.00 136.92 ? 361 ALA A C   1 
ATOM   1570  O O   . ALA A 1 362 ? 119.828 66.432  132.132 1.00 154.43 ? 361 ALA A O   1 
ATOM   1571  C CB  . ALA A 1 362 ? 121.313 68.010  134.580 1.00 222.10 ? 361 ALA A CB  1 
ATOM   1572  N N   . GLU A 1 363 ? 119.392 65.463  134.145 1.00 138.58 ? 362 GLU A N   1 
ATOM   1573  C CA  . GLU A 1 363 ? 119.177 64.136  133.593 1.00 170.19 ? 362 GLU A CA  1 
ATOM   1574  C C   . GLU A 1 363 ? 117.905 64.143  132.732 1.00 141.84 ? 362 GLU A C   1 
ATOM   1575  O O   . GLU A 1 363 ? 117.929 63.672  131.582 1.00 123.91 ? 362 GLU A O   1 
ATOM   1576  C CB  . GLU A 1 363 ? 119.125 63.115  134.732 1.00 214.00 ? 362 GLU A CB  1 
ATOM   1577  C CG  . GLU A 1 363 ? 118.928 61.680  134.262 1.00 225.39 ? 362 GLU A CG  1 
ATOM   1578  C CD  . GLU A 1 363 ? 118.846 60.638  135.368 1.00 283.39 ? 362 GLU A CD  1 
ATOM   1579  O OE1 . GLU A 1 363 ? 118.151 60.891  136.378 1.00 281.35 ? 362 GLU A OE1 1 
ATOM   1580  O OE2 . GLU A 1 363 ? 119.469 59.562  135.214 1.00 346.30 ? 362 GLU A OE2 1 
ATOM   1581  N N   . TRP A 1 364 ? 116.804 64.671  133.302 1.00 88.92  ? 363 TRP A N   1 
ATOM   1582  C CA  . TRP A 1 364 ? 115.520 64.681  132.627 1.00 91.62  ? 363 TRP A CA  1 
ATOM   1583  C C   . TRP A 1 364 ? 115.521 65.552  131.372 1.00 101.43 ? 363 TRP A C   1 
ATOM   1584  O O   . TRP A 1 364 ? 114.835 65.250  130.388 1.00 111.66 ? 363 TRP A O   1 
ATOM   1585  C CB  . TRP A 1 364 ? 114.452 65.176  133.601 1.00 83.09  ? 363 TRP A CB  1 
ATOM   1586  C CG  . TRP A 1 364 ? 114.294 64.345  134.827 1.00 88.04  ? 363 TRP A CG  1 
ATOM   1587  C CD1 . TRP A 1 364 ? 114.630 63.047  134.978 1.00 117.11 ? 363 TRP A CD1 1 
ATOM   1588  C CD2 . TRP A 1 364 ? 113.757 64.781  136.083 1.00 91.95  ? 363 TRP A CD2 1 
ATOM   1589  N NE1 . TRP A 1 364 ? 114.343 62.647  136.244 1.00 119.39 ? 363 TRP A NE1 1 
ATOM   1590  C CE2 . TRP A 1 364 ? 113.804 63.680  136.941 1.00 91.95  ? 363 TRP A CE2 1 
ATOM   1591  C CE3 . TRP A 1 364 ? 113.242 65.983  136.558 1.00 89.05  ? 363 TRP A CE3 1 
ATOM   1592  C CZ2 . TRP A 1 364 ? 113.365 63.740  138.253 1.00 132.66 ? 363 TRP A CZ2 1 
ATOM   1593  C CZ3 . TRP A 1 364 ? 112.794 66.037  137.853 1.00 112.52 ? 363 TRP A CZ3 1 
ATOM   1594  C CH2 . TRP A 1 364 ? 112.867 64.937  138.695 1.00 144.02 ? 363 TRP A CH2 1 
ATOM   1595  N N   . GLN A 1 365 ? 116.267 66.649  131.439 1.00 88.09  ? 364 GLN A N   1 
ATOM   1596  C CA  . GLN A 1 365 ? 116.423 67.529  130.303 1.00 104.75 ? 364 GLN A CA  1 
ATOM   1597  C C   . GLN A 1 365 ? 117.171 66.774  129.213 1.00 127.12 ? 364 GLN A C   1 
ATOM   1598  O O   . GLN A 1 365 ? 116.740 66.819  128.066 1.00 173.74 ? 364 GLN A O   1 
ATOM   1599  C CB  . GLN A 1 365 ? 117.092 68.813  130.799 1.00 128.76 ? 364 GLN A CB  1 
ATOM   1600  C CG  . GLN A 1 365 ? 117.449 69.806  129.728 1.00 150.79 ? 364 GLN A CG  1 
ATOM   1601  C CD  . GLN A 1 365 ? 116.287 70.550  129.136 1.00 178.25 ? 364 GLN A CD  1 
ATOM   1602  O OE1 . GLN A 1 365 ? 115.124 70.195  129.244 1.00 181.80 ? 364 GLN A OE1 1 
ATOM   1603  N NE2 . GLN A 1 365 ? 116.625 71.625  128.460 1.00 253.27 ? 364 GLN A NE2 1 
ATOM   1604  N N   . ASN A 1 366 ? 118.277 66.098  129.565 1.00 156.17 ? 365 ASN A N   1 
ATOM   1605  C CA  . ASN A 1 366 ? 119.007 65.285  128.602 1.00 150.94 ? 365 ASN A CA  1 
ATOM   1606  C C   . ASN A 1 366 ? 118.084 64.246  127.979 1.00 154.30 ? 365 ASN A C   1 
ATOM   1607  O O   . ASN A 1 366 ? 118.128 64.080  126.762 1.00 184.81 ? 365 ASN A O   1 
ATOM   1608  C CB  . ASN A 1 366 ? 120.242 64.619  129.210 1.00 226.39 ? 365 ASN A CB  1 
ATOM   1609  C CG  . ASN A 1 366 ? 121.520 65.294  128.767 1.00 315.33 ? 365 ASN A CG  1 
ATOM   1610  O OD1 . ASN A 1 366 ? 121.730 66.464  129.080 1.00 331.35 ? 365 ASN A OD1 1 
ATOM   1611  N ND2 . ASN A 1 366 ? 122.358 64.565  128.040 1.00 365.65 ? 365 ASN A ND2 1 
ATOM   1612  N N   . ILE A 1 367 ? 117.262 63.556  128.792 1.00 131.45 ? 366 ILE A N   1 
ATOM   1613  C CA  . ILE A 1 367 ? 116.331 62.552  128.271 1.00 128.31 ? 366 ILE A CA  1 
ATOM   1614  C C   . ILE A 1 367 ? 115.373 63.161  127.254 1.00 117.42 ? 366 ILE A C   1 
ATOM   1615  O O   . ILE A 1 367 ? 115.152 62.561  126.190 1.00 125.89 ? 366 ILE A O   1 
ATOM   1616  C CB  . ILE A 1 367 ? 115.613 61.840  129.416 1.00 128.77 ? 366 ILE A CB  1 
ATOM   1617  C CG1 . ILE A 1 367 ? 116.615 60.962  130.179 1.00 208.14 ? 366 ILE A CG1 1 
ATOM   1618  C CG2 . ILE A 1 367 ? 114.439 61.018  128.910 1.00 161.87 ? 366 ILE A CG2 1 
ATOM   1619  C CD1 . ILE A 1 367 ? 116.206 60.612  131.591 1.00 288.08 ? 366 ILE A CD1 1 
ATOM   1620  N N   . THR A 1 368 ? 114.856 64.356  127.574 1.00 130.06 ? 367 THR A N   1 
ATOM   1621  C CA  . THR A 1 368 ? 113.866 65.017  126.732 1.00 132.00 ? 367 THR A CA  1 
ATOM   1622  C C   . THR A 1 368 ? 114.520 65.521  125.436 1.00 134.99 ? 367 THR A C   1 
ATOM   1623  O O   . THR A 1 368 ? 114.083 65.144  124.367 1.00 182.14 ? 367 THR A O   1 
ATOM   1624  C CB  . THR A 1 368 ? 113.148 66.152  127.474 1.00 124.77 ? 367 THR A CB  1 
ATOM   1625  O OG1 . THR A 1 368 ? 112.614 65.542  128.659 1.00 113.71 ? 367 THR A OG1 1 
ATOM   1626  C CG2 . THR A 1 368 ? 112.157 66.903  126.583 1.00 98.96  ? 367 THR A CG2 1 
ATOM   1627  N N   . LYS A 1 369 ? 115.553 66.361  125.499 1.00 128.55 ? 368 LYS A N   1 
ATOM   1628  C CA  . LYS A 1 369 ? 116.176 66.892  124.301 1.00 144.03 ? 368 LYS A CA  1 
ATOM   1629  C C   . LYS A 1 369 ? 116.816 65.779  123.470 1.00 168.67 ? 368 LYS A C   1 
ATOM   1630  O O   . LYS A 1 369 ? 116.883 65.894  122.245 1.00 159.61 ? 368 LYS A O   1 
ATOM   1631  C CB  . LYS A 1 369 ? 117.207 67.944  124.702 1.00 198.52 ? 368 LYS A CB  1 
ATOM   1632  C CG  . LYS A 1 369 ? 116.586 69.256  125.152 1.00 187.17 ? 368 LYS A CG  1 
ATOM   1633  C CD  . LYS A 1 369 ? 116.227 70.098  123.988 1.00 266.73 ? 368 LYS A CD  1 
ATOM   1634  C CE  . LYS A 1 369 ? 115.872 71.526  124.338 1.00 304.83 ? 368 LYS A CE  1 
ATOM   1635  N NZ  . LYS A 1 369 ? 115.846 72.388  123.126 1.00 311.18 ? 368 LYS A NZ  1 
ATOM   1636  N N   . GLY A 1 370 ? 117.292 64.716  124.138 1.00 194.96 ? 369 GLY A N   1 
ATOM   1637  C CA  . GLY A 1 370 ? 117.796 63.516  123.480 1.00 246.78 ? 369 GLY A CA  1 
ATOM   1638  C C   . GLY A 1 370 ? 116.739 62.767  122.674 1.00 194.35 ? 369 GLY A C   1 
ATOM   1639  O O   . GLY A 1 370 ? 117.096 62.029  121.753 1.00 224.34 ? 369 GLY A O   1 
ATOM   1640  N N   . PHE A 1 371 ? 115.460 62.953  123.021 1.00 140.44 ? 370 PHE A N   1 
ATOM   1641  C CA  . PHE A 1 371 ? 114.374 62.442  122.203 1.00 141.90 ? 370 PHE A CA  1 
ATOM   1642  C C   . PHE A 1 371 ? 114.174 63.293  120.959 1.00 135.26 ? 370 PHE A C   1 
ATOM   1643  O O   . PHE A 1 371 ? 114.223 62.780  119.841 1.00 209.90 ? 370 PHE A O   1 
ATOM   1644  C CB  . PHE A 1 371 ? 113.069 62.369  122.989 1.00 140.58 ? 370 PHE A CB  1 
ATOM   1645  C CG  . PHE A 1 371 ? 112.063 61.450  122.358 1.00 144.86 ? 370 PHE A CG  1 
ATOM   1646  C CD1 . PHE A 1 371 ? 111.279 61.897  121.298 1.00 136.67 ? 370 PHE A CD1 1 
ATOM   1647  C CD2 . PHE A 1 371 ? 111.941 60.131  122.818 1.00 164.02 ? 370 PHE A CD2 1 
ATOM   1648  C CE1 . PHE A 1 371 ? 110.353 61.030  120.725 1.00 208.40 ? 370 PHE A CE1 1 
ATOM   1649  C CE2 . PHE A 1 371 ? 111.028 59.267  122.237 1.00 185.72 ? 370 PHE A CE2 1 
ATOM   1650  C CZ  . PHE A 1 371 ? 110.233 59.717  121.193 1.00 234.91 ? 370 PHE A CZ  1 
ATOM   1651  N N   . SER A 1 372 ? 113.934 64.585  121.162 1.00 138.47 ? 371 SER A N   1 
ATOM   1652  C CA  . SER A 1 372 ? 113.779 65.528  120.058 1.00 187.65 ? 371 SER A CA  1 
ATOM   1653  C C   . SER A 1 372 ? 114.027 66.948  120.553 1.00 154.87 ? 371 SER A C   1 
ATOM   1654  O O   . SER A 1 372 ? 113.861 67.230  121.729 1.00 171.58 ? 371 SER A O   1 
ATOM   1655  C CB  . SER A 1 372 ? 112.426 65.396  119.370 1.00 192.33 ? 371 SER A CB  1 
ATOM   1656  O OG  . SER A 1 372 ? 112.246 66.363  118.323 1.00 154.35 ? 371 SER A OG  1 
ATOM   1657  N N   . GLU A 1 373 ? 114.434 67.829  119.631 1.00 180.52 ? 372 GLU A N   1 
ATOM   1658  C CA  . GLU A 1 373 ? 114.839 69.192  119.970 1.00 182.68 ? 372 GLU A CA  1 
ATOM   1659  C C   . GLU A 1 373 ? 113.598 70.046  120.269 1.00 142.65 ? 372 GLU A C   1 
ATOM   1660  O O   . GLU A 1 373 ? 113.712 71.043  120.988 1.00 171.91 ? 372 GLU A O   1 
ATOM   1661  C CB  . GLU A 1 373 ? 115.755 69.792  118.893 1.00 222.61 ? 372 GLU A CB  1 
ATOM   1662  C CG  . GLU A 1 373 ? 115.200 69.770  117.463 1.00 359.32 ? 372 GLU A CG  1 
ATOM   1663  C CD  . GLU A 1 373 ? 116.097 70.421  116.421 1.00 504.17 ? 372 GLU A CD  1 
ATOM   1664  O OE1 . GLU A 1 373 ? 116.492 71.587  116.638 1.00 593.24 ? 372 GLU A OE1 1 
ATOM   1665  O OE2 . GLU A 1 373 ? 116.398 69.768  115.394 1.00 590.75 ? 372 GLU A OE2 1 
ATOM   1666  N N   . ASP A 1 374 ? 112.411 69.658  119.759 1.00 115.32 ? 373 ASP A N   1 
ATOM   1667  C CA  . ASP A 1 374 ? 111.171 70.397  119.958 1.00 128.66 ? 373 ASP A CA  1 
ATOM   1668  C C   . ASP A 1 374 ? 110.308 69.832  121.104 1.00 110.16 ? 373 ASP A C   1 
ATOM   1669  O O   . ASP A 1 374 ? 109.069 69.792  120.982 1.00 138.89 ? 373 ASP A O   1 
ATOM   1670  C CB  . ASP A 1 374 ? 110.442 70.562  118.601 1.00 189.32 ? 373 ASP A CB  1 
ATOM   1671  C CG  . ASP A 1 374 ? 110.917 71.794  117.816 1.00 261.48 ? 373 ASP A CG  1 
ATOM   1672  O OD1 . ASP A 1 374 ? 112.171 71.970  117.696 1.00 315.31 ? 373 ASP A OD1 1 
ATOM   1673  O OD2 . ASP A 1 374 ? 110.049 72.592  117.322 1.00 243.50 ? 373 ASP A OD2 1 
ATOM   1674  N N   . ARG A 1 375 ? 110.930 69.465  122.233 1.00 79.73  ? 374 ARG A N   1 
ATOM   1675  C CA  . ARG A 1 375 ? 110.213 69.144  123.464 1.00 90.96  ? 374 ARG A CA  1 
ATOM   1676  C C   . ARG A 1 375 ? 110.849 69.866  124.632 1.00 107.20 ? 374 ARG A C   1 
ATOM   1677  O O   . ARG A 1 375 ? 112.085 70.035  124.630 1.00 154.33 ? 374 ARG A O   1 
ATOM   1678  C CB  . ARG A 1 375 ? 110.216 67.631  123.758 1.00 76.21  ? 374 ARG A CB  1 
ATOM   1679  C CG  . ARG A 1 375 ? 109.151 66.885  122.981 1.00 97.96  ? 374 ARG A CG  1 
ATOM   1680  C CD  . ARG A 1 375 ? 109.640 66.237  121.719 1.00 128.23 ? 374 ARG A CD  1 
ATOM   1681  N NE  . ARG A 1 375 ? 108.598 66.082  120.701 1.00 143.05 ? 374 ARG A NE  1 
ATOM   1682  C CZ  . ARG A 1 375 ? 107.734 65.080  120.602 1.00 175.19 ? 374 ARG A CZ  1 
ATOM   1683  N NH1 . ARG A 1 375 ? 106.842 65.080  119.625 1.00 268.80 ? 374 ARG A NH1 1 
ATOM   1684  N NH2 . ARG A 1 375 ? 107.737 64.074  121.466 1.00 101.16 ? 374 ARG A NH2 1 
ATOM   1685  N N   . LEU A 1 376 ? 110.002 70.257  125.626 1.00 68.53  ? 375 LEU A N   1 
ATOM   1686  C CA  . LEU A 1 376 ? 110.576 70.995  126.760 1.00 96.80  ? 375 LEU A CA  1 
ATOM   1687  C C   . LEU A 1 376 ? 110.218 70.457  128.126 1.00 69.63  ? 375 LEU A C   1 
ATOM   1688  O O   . LEU A 1 376 ? 109.236 69.784  128.241 1.00 69.92  ? 375 LEU A O   1 
ATOM   1689  C CB  . LEU A 1 376 ? 110.293 72.502  126.794 1.00 87.77  ? 375 LEU A CB  1 
ATOM   1690  C CG  . LEU A 1 376 ? 108.958 72.939  127.302 1.00 68.26  ? 375 LEU A CG  1 
ATOM   1691  C CD1 . LEU A 1 376 ? 108.817 74.427  127.329 1.00 77.13  ? 375 LEU A CD1 1 
ATOM   1692  C CD2 . LEU A 1 376 ? 108.000 72.400  126.344 1.00 107.96 ? 375 LEU A CD2 1 
ATOM   1693  N N   . LEU A 1 377 ? 111.093 70.801  129.082 1.00 75.21  ? 376 LEU A N   1 
ATOM   1694  C CA  . LEU A 1 377 ? 110.890 70.561  130.486 1.00 71.64  ? 376 LEU A CA  1 
ATOM   1695  C C   . LEU A 1 377 ? 110.775 71.934  131.168 1.00 60.61  ? 376 LEU A C   1 
ATOM   1696  O O   . LEU A 1 377 ? 111.713 72.693  131.221 1.00 91.36  ? 376 LEU A O   1 
ATOM   1697  C CB  . LEU A 1 377 ? 111.969 69.558  130.964 1.00 67.32  ? 376 LEU A CB  1 
ATOM   1698  C CG  . LEU A 1 377 ? 112.051 69.383  132.473 1.00 94.51  ? 376 LEU A CG  1 
ATOM   1699  C CD1 . LEU A 1 377 ? 110.894 68.568  133.052 1.00 139.59 ? 376 LEU A CD1 1 
ATOM   1700  C CD2 . LEU A 1 377 ? 113.351 68.725  132.822 1.00 142.36 ? 376 LEU A CD2 1 
ATOM   1701  N N   . ILE A 1 378 ? 109.589 72.256  131.701 1.00 68.02  ? 377 ILE A N   1 
ATOM   1702  C CA  . ILE A 1 378 ? 109.292 73.417  132.534 1.00 58.03  ? 377 ILE A CA  1 
ATOM   1703  C C   . ILE A 1 378 ? 109.439 73.046  134.004 1.00 62.46  ? 377 ILE A C   1 
ATOM   1704  O O   . ILE A 1 378 ? 108.624 72.401  134.625 1.00 71.45  ? 377 ILE A O   1 
ATOM   1705  C CB  . ILE A 1 378 ? 107.854 73.805  132.267 1.00 65.52  ? 377 ILE A CB  1 
ATOM   1706  C CG1 . ILE A 1 378 ? 107.687 74.219  130.835 1.00 72.28  ? 377 ILE A CG1 1 
ATOM   1707  C CG2 . ILE A 1 378 ? 107.374 74.911  133.151 1.00 115.33 ? 377 ILE A CG2 1 
ATOM   1708  C CD1 . ILE A 1 378 ? 106.257 74.586  130.550 1.00 135.05 ? 377 ILE A CD1 1 
ATOM   1709  N N   . ALA A 1 379 ? 110.523 73.435  134.622 1.00 72.67  ? 378 ALA A N   1 
ATOM   1710  C CA  . ALA A 1 379 ? 110.627 73.297  136.076 1.00 62.15  ? 378 ALA A CA  1 
ATOM   1711  C C   . ALA A 1 379 ? 109.923 74.411  136.776 1.00 54.73  ? 378 ALA A C   1 
ATOM   1712  O O   . ALA A 1 379 ? 109.599 75.429  136.181 1.00 72.92  ? 378 ALA A O   1 
ATOM   1713  C CB  . ALA A 1 379 ? 112.018 73.387  136.541 1.00 79.93  ? 378 ALA A CB  1 
ATOM   1714  N N   . GLY A 1 380 ? 109.655 74.191  138.051 1.00 67.45  ? 379 GLY A N   1 
ATOM   1715  C CA  . GLY A 1 380 ? 108.989 75.245  138.809 1.00 83.20  ? 379 GLY A CA  1 
ATOM   1716  C C   . GLY A 1 380 ? 109.323 75.150  140.272 1.00 67.93  ? 379 GLY A C   1 
ATOM   1717  O O   . GLY A 1 380 ? 109.396 74.067  140.790 1.00 120.38 ? 379 GLY A O   1 
ATOM   1718  N N   . THR A 1 381 ? 109.525 76.278  140.906 1.00 75.09  ? 380 THR A N   1 
ATOM   1719  C CA  . THR A 1 381 ? 109.896 76.336  142.296 1.00 68.29  ? 380 THR A CA  1 
ATOM   1720  C C   . THR A 1 381 ? 109.050 77.390  143.051 1.00 76.90  ? 380 THR A C   1 
ATOM   1721  O O   . THR A 1 381 ? 108.566 78.359  142.480 1.00 73.39  ? 380 THR A O   1 
ATOM   1722  C CB  . THR A 1 381 ? 111.356 76.730  142.415 1.00 74.44  ? 380 THR A CB  1 
ATOM   1723  O OG1 . THR A 1 381 ? 111.590 76.869  143.826 1.00 117.74 ? 380 THR A OG1 1 
ATOM   1724  C CG2 . THR A 1 381 ? 111.705 78.019  141.699 1.00 77.61  ? 380 THR A CG2 1 
ATOM   1725  N N   . ASN A 1 382 ? 108.890 77.185  144.356 1.00 83.19  ? 381 ASN A N   1 
ATOM   1726  C CA  . ASN A 1 382 ? 108.209 78.131  145.214 1.00 84.15  ? 381 ASN A CA  1 
ATOM   1727  C C   . ASN A 1 382 ? 109.127 79.315  145.504 1.00 77.72  ? 381 ASN A C   1 
ATOM   1728  O O   . ASN A 1 382 ? 108.617 80.345  145.992 1.00 137.81 ? 381 ASN A O   1 
ATOM   1729  C CB  . ASN A 1 382 ? 107.660 77.473  146.475 1.00 117.24 ? 381 ASN A CB  1 
ATOM   1730  C CG  . ASN A 1 382 ? 108.706 77.337  147.553 1.00 193.56 ? 381 ASN A CG  1 
ATOM   1731  O OD1 . ASN A 1 382 ? 109.905 77.379  147.277 1.00 195.31 ? 381 ASN A OD1 1 
ATOM   1732  N ND2 . ASN A 1 382 ? 108.218 77.181  148.776 1.00 270.39 ? 381 ASN A ND2 1 
ATOM   1733  N N   . SER A 1 383 ? 110.423 79.193  145.148 1.00 72.01  ? 382 SER A N   1 
ATOM   1734  C CA  . SER A 1 383 ? 111.405 80.270  145.336 1.00 127.27 ? 382 SER A CA  1 
ATOM   1735  C C   . SER A 1 383 ? 111.082 81.677  144.781 1.00 103.51 ? 382 SER A C   1 
ATOM   1736  O O   . SER A 1 383 ? 110.440 81.803  143.757 1.00 102.79 ? 382 SER A O   1 
ATOM   1737  C CB  . SER A 1 383 ? 112.693 79.904  144.723 1.00 123.25 ? 382 SER A CB  1 
ATOM   1738  O OG  . SER A 1 383 ? 113.648 80.780  145.265 1.00 143.47 ? 382 SER A OG  1 
ATOM   1739  N N   . SER A 1 384 ? 111.527 82.713  145.511 1.00 82.20  ? 383 SER A N   1 
ATOM   1740  C CA  . SER A 1 384 ? 111.571 84.073  145.045 1.00 87.03  ? 383 SER A CA  1 
ATOM   1741  C C   . SER A 1 384 ? 112.949 84.701  145.244 1.00 101.01 ? 383 SER A C   1 
ATOM   1742  O O   . SER A 1 384 ? 113.094 85.933  145.172 1.00 113.63 ? 383 SER A O   1 
ATOM   1743  C CB  . SER A 1 384 ? 110.499 84.889  145.704 1.00 136.22 ? 383 SER A CB  1 
ATOM   1744  O OG  . SER A 1 384 ? 110.780 85.234  147.062 1.00 169.41 ? 383 SER A OG  1 
ATOM   1745  N N   . ASP A 1 385 ? 113.983 83.874  145.432 1.00 115.76 ? 384 ASP A N   1 
ATOM   1746  C CA  . ASP A 1 385 ? 115.338 84.371  145.601 1.00 132.48 ? 384 ASP A CA  1 
ATOM   1747  C C   . ASP A 1 385 ? 116.026 84.364  144.246 1.00 109.01 ? 384 ASP A C   1 
ATOM   1748  O O   . ASP A 1 385 ? 116.176 83.319  143.593 1.00 165.56 ? 384 ASP A O   1 
ATOM   1749  C CB  . ASP A 1 385 ? 116.142 83.484  146.550 1.00 228.15 ? 384 ASP A CB  1 
ATOM   1750  C CG  . ASP A 1 385 ? 117.642 83.744  146.509 1.00 268.71 ? 384 ASP A CG  1 
ATOM   1751  O OD1 . ASP A 1 385 ? 118.037 84.891  146.202 1.00 296.80 ? 384 ASP A OD1 1 
ATOM   1752  O OD2 . ASP A 1 385 ? 118.415 82.792  146.752 1.00 266.40 ? 384 ASP A OD2 1 
ATOM   1753  N N   . LEU A 1 386 ? 116.501 85.521  143.810 1.00 82.36  ? 385 LEU A N   1 
ATOM   1754  C CA  . LEU A 1 386 ? 117.152 85.581  142.505 1.00 102.10 ? 385 LEU A CA  1 
ATOM   1755  C C   . LEU A 1 386 ? 118.331 84.600  142.373 1.00 130.40 ? 385 LEU A C   1 
ATOM   1756  O O   . LEU A 1 386 ? 118.575 84.028  141.310 1.00 112.55 ? 385 LEU A O   1 
ATOM   1757  C CB  . LEU A 1 386 ? 117.643 87.013  142.312 1.00 103.93 ? 385 LEU A CB  1 
ATOM   1758  C CG  . LEU A 1 386 ? 118.424 87.229  141.035 1.00 107.87 ? 385 LEU A CG  1 
ATOM   1759  C CD1 . LEU A 1 386 ? 117.626 86.738  139.856 1.00 93.21  ? 385 LEU A CD1 1 
ATOM   1760  C CD2 . LEU A 1 386 ? 118.771 88.707  140.882 1.00 184.16 ? 385 LEU A CD2 1 
ATOM   1761  N N   . GLN A 1 387 ? 119.104 84.427  143.453 1.00 146.81 ? 386 GLN A N   1 
ATOM   1762  C CA  . GLN A 1 387 ? 120.324 83.647  143.387 1.00 169.55 ? 386 GLN A CA  1 
ATOM   1763  C C   . GLN A 1 387 ? 120.000 82.161  143.334 1.00 136.10 ? 386 GLN A C   1 
ATOM   1764  O O   . GLN A 1 387 ? 120.610 81.448  142.540 1.00 154.58 ? 386 GLN A O   1 
ATOM   1765  C CB  . GLN A 1 387 ? 121.233 84.034  144.556 1.00 230.72 ? 386 GLN A CB  1 
ATOM   1766  C CG  . GLN A 1 387 ? 121.760 85.471  144.443 1.00 219.61 ? 386 GLN A CG  1 
ATOM   1767  C CD  . GLN A 1 387 ? 122.640 85.694  143.232 1.00 251.79 ? 386 GLN A CD  1 
ATOM   1768  O OE1 . GLN A 1 387 ? 123.153 84.738  142.640 1.00 238.48 ? 386 GLN A OE1 1 
ATOM   1769  N NE2 . GLN A 1 387 ? 122.819 86.959  142.861 1.00 241.36 ? 386 GLN A NE2 1 
ATOM   1770  N N   . GLN A 1 388 ? 119.055 81.694  144.160 1.00 124.36 ? 387 GLN A N   1 
ATOM   1771  C CA  . GLN A 1 388 ? 118.631 80.297  144.103 1.00 157.68 ? 387 GLN A CA  1 
ATOM   1772  C C   . GLN A 1 388 ? 118.155 79.952  142.678 1.00 128.80 ? 387 GLN A C   1 
ATOM   1773  O O   . GLN A 1 388 ? 118.548 78.946  142.063 1.00 116.40 ? 387 GLN A O   1 
ATOM   1774  C CB  . GLN A 1 388 ? 117.602 80.024  145.199 1.00 120.33 ? 387 GLN A CB  1 
ATOM   1775  C CG  . GLN A 1 388 ? 117.244 78.555  145.311 1.00 182.19 ? 387 GLN A CG  1 
ATOM   1776  C CD  . GLN A 1 388 ? 116.090 78.269  146.251 1.00 293.45 ? 387 GLN A CD  1 
ATOM   1777  O OE1 . GLN A 1 388 ? 115.351 79.162  146.671 1.00 341.25 ? 387 GLN A OE1 1 
ATOM   1778  N NE2 . GLN A 1 388 ? 115.905 77.001  146.582 1.00 322.17 ? 387 GLN A NE2 1 
ATOM   1779  N N   . ILE A 1 389 ? 117.333 80.815  142.116 1.00 111.04 ? 388 ILE A N   1 
ATOM   1780  C CA  . ILE A 1 389 ? 116.848 80.620  140.764 1.00 91.46  ? 388 ILE A CA  1 
ATOM   1781  C C   . ILE A 1 389 ? 118.000 80.599  139.768 1.00 93.59  ? 388 ILE A C   1 
ATOM   1782  O O   . ILE A 1 389 ? 118.035 79.698  138.923 1.00 140.74 ? 388 ILE A O   1 
ATOM   1783  C CB  . ILE A 1 389 ? 115.778 81.683  140.448 1.00 81.92  ? 388 ILE A CB  1 
ATOM   1784  C CG1 . ILE A 1 389 ? 114.516 81.352  141.239 1.00 102.27 ? 388 ILE A CG1 1 
ATOM   1785  C CG2 . ILE A 1 389 ? 115.512 81.773  138.968 1.00 98.20  ? 388 ILE A CG2 1 
ATOM   1786  C CD1 . ILE A 1 389 ? 113.596 82.490  141.483 1.00 102.71 ? 388 ILE A CD1 1 
ATOM   1787  N N   . LEU A 1 390 ? 118.917 81.559  139.839 1.00 124.49 ? 389 LEU A N   1 
ATOM   1788  C CA  . LEU A 1 390 ? 120.026 81.574  138.901 1.00 141.16 ? 389 LEU A CA  1 
ATOM   1789  C C   . LEU A 1 390 ? 120.872 80.309  139.039 1.00 137.67 ? 389 LEU A C   1 
ATOM   1790  O O   . LEU A 1 390 ? 121.496 79.934  138.043 1.00 122.16 ? 389 LEU A O   1 
ATOM   1791  C CB  . LEU A 1 390 ? 120.861 82.830  139.143 1.00 166.16 ? 389 LEU A CB  1 
ATOM   1792  C CG  . LEU A 1 390 ? 120.260 84.098  138.547 1.00 192.85 ? 389 LEU A CG  1 
ATOM   1793  C CD1 . LEU A 1 390 ? 120.840 85.312  139.231 1.00 200.53 ? 389 LEU A CD1 1 
ATOM   1794  C CD2 . LEU A 1 390 ? 120.497 84.155  137.031 1.00 234.21 ? 389 LEU A CD2 1 
ATOM   1795  N N   . SER A 1 391 ? 120.911 79.675  140.236 1.00 119.56 ? 390 SER A N   1 
ATOM   1796  C CA  . SER A 1 391 ? 121.681 78.455  140.439 1.00 161.62 ? 390 SER A CA  1 
ATOM   1797  C C   . SER A 1 391 ? 121.027 77.260  139.733 1.00 137.37 ? 390 SER A C   1 
ATOM   1798  O O   . SER A 1 391 ? 121.754 76.451  139.128 1.00 173.65 ? 390 SER A O   1 
ATOM   1799  C CB  . SER A 1 391 ? 121.954 78.204  141.918 1.00 178.84 ? 390 SER A CB  1 
ATOM   1800  O OG  . SER A 1 391 ? 120.821 77.692  142.592 1.00 176.99 ? 390 SER A OG  1 
ATOM   1801  N N   . LEU A 1 392 ? 119.688 77.132  139.808 1.00 113.58 ? 391 LEU A N   1 
ATOM   1802  C CA  . LEU A 1 392 ? 118.953 76.065  139.092 1.00 126.94 ? 391 LEU A CA  1 
ATOM   1803  C C   . LEU A 1 392 ? 119.067 76.245  137.583 1.00 119.92 ? 391 LEU A C   1 
ATOM   1804  O O   . LEU A 1 392 ? 119.081 75.267  136.851 1.00 167.46 ? 391 LEU A O   1 
ATOM   1805  C CB  . LEU A 1 392 ? 117.464 76.013  139.466 1.00 89.80  ? 391 LEU A CB  1 
ATOM   1806  C CG  . LEU A 1 392 ? 117.078 75.412  140.827 1.00 153.71 ? 391 LEU A CG  1 
ATOM   1807  C CD1 . LEU A 1 392 ? 118.224 75.334  141.842 1.00 241.55 ? 391 LEU A CD1 1 
ATOM   1808  C CD2 . LEU A 1 392 ? 115.927 76.196  141.506 1.00 144.85 ? 391 LEU A CD2 1 
ATOM   1809  N N   . LEU A 1 393 ? 119.148 77.489  137.128 1.00 124.00 ? 392 LEU A N   1 
ATOM   1810  C CA  . LEU A 1 393 ? 119.334 77.824  135.732 1.00 118.98 ? 392 LEU A CA  1 
ATOM   1811  C C   . LEU A 1 393 ? 120.810 77.900  135.301 1.00 160.06 ? 392 LEU A C   1 
ATOM   1812  O O   . LEU A 1 393 ? 121.096 78.377  134.173 1.00 264.87 ? 392 LEU A O   1 
ATOM   1813  C CB  . LEU A 1 393 ? 118.725 79.221  135.555 1.00 166.90 ? 392 LEU A CB  1 
ATOM   1814  C CG  . LEU A 1 393 ? 117.253 79.324  135.280 1.00 124.98 ? 392 LEU A CG  1 
ATOM   1815  C CD1 . LEU A 1 393 ? 116.794 80.743  135.660 1.00 168.55 ? 392 LEU A CD1 1 
ATOM   1816  C CD2 . LEU A 1 393 ? 116.993 79.035  133.815 1.00 244.18 ? 392 LEU A CD2 1 
ATOM   1817  N N   . GLU A 1 394 ? 121.780 77.484  136.139 1.00 160.55 ? 393 GLU A N   1 
ATOM   1818  C CA  . GLU A 1 394 ? 123.181 77.640  135.757 1.00 228.02 ? 393 GLU A CA  1 
ATOM   1819  C C   . GLU A 1 394 ? 123.611 76.473  134.872 1.00 213.06 ? 393 GLU A C   1 
ATOM   1820  O O   . GLU A 1 394 ? 124.143 76.679  133.784 1.00 200.22 ? 393 GLU A O   1 
ATOM   1821  C CB  . GLU A 1 394 ? 124.077 77.748  136.987 1.00 272.26 ? 393 GLU A CB  1 
ATOM   1822  C CG  . GLU A 1 394 ? 125.529 78.040  136.649 1.00 313.73 ? 393 GLU A CG  1 
ATOM   1823  C CD  . GLU A 1 394 ? 126.278 78.833  137.712 1.00 365.33 ? 393 GLU A CD  1 
ATOM   1824  O OE1 . GLU A 1 394 ? 126.185 78.456  138.900 1.00 388.16 ? 393 GLU A OE1 1 
ATOM   1825  O OE2 . GLU A 1 394 ? 126.959 79.829  137.356 1.00 398.11 ? 393 GLU A OE2 1 
ATOM   1826  N N   . SER A 1 395 ? 123.379 75.263  135.378 1.00 187.45 ? 394 SER A N   1 
ATOM   1827  C CA  . SER A 1 395 ? 123.733 74.016  134.722 1.00 171.36 ? 394 SER A CA  1 
ATOM   1828  C C   . SER A 1 395 ? 122.766 73.666  133.581 1.00 193.39 ? 394 SER A C   1 
ATOM   1829  O O   . SER A 1 395 ? 123.143 72.950  132.650 1.00 200.05 ? 394 SER A O   1 
ATOM   1830  C CB  . SER A 1 395 ? 123.751 72.881  135.743 1.00 238.32 ? 394 SER A CB  1 
ATOM   1831  O OG  . SER A 1 395 ? 124.497 73.176  136.921 1.00 280.68 ? 394 SER A OG  1 
ATOM   1832  N N   . ASN A 1 396 ? 121.519 74.151  133.657 1.00 201.49 ? 395 ASN A N   1 
ATOM   1833  C CA  . ASN A 1 396 ? 120.465 73.858  132.697 1.00 168.67 ? 395 ASN A CA  1 
ATOM   1834  C C   . ASN A 1 396 ? 120.118 75.140  131.963 1.00 169.94 ? 395 ASN A C   1 
ATOM   1835  O O   . ASN A 1 396 ? 119.776 76.139  132.574 1.00 177.98 ? 395 ASN A O   1 
ATOM   1836  C CB  . ASN A 1 396 ? 119.255 73.263  133.408 1.00 191.99 ? 395 ASN A CB  1 
ATOM   1837  C CG  . ASN A 1 396 ? 119.612 71.954  134.055 1.00 201.54 ? 395 ASN A CG  1 
ATOM   1838  O OD1 . ASN A 1 396 ? 119.976 71.020  133.347 1.00 237.43 ? 395 ASN A OD1 1 
ATOM   1839  N ND2 . ASN A 1 396 ? 119.527 71.879  135.373 1.00 193.75 ? 395 ASN A ND2 1 
ATOM   1840  N N   . LYS A 1 397 ? 120.213 75.113  130.640 1.00 167.25 ? 396 LYS A N   1 
ATOM   1841  C CA  . LYS A 1 397 ? 120.329 76.344  129.882 1.00 189.57 ? 396 LYS A CA  1 
ATOM   1842  C C   . LYS A 1 397 ? 119.140 76.507  128.937 1.00 180.82 ? 396 LYS A C   1 
ATOM   1843  O O   . LYS A 1 397 ? 118.895 77.656  128.541 1.00 216.77 ? 396 LYS A O   1 
ATOM   1844  C CB  . LYS A 1 397 ? 121.697 76.320  129.192 1.00 297.01 ? 396 LYS A CB  1 
ATOM   1845  C CG  . LYS A 1 397 ? 122.859 75.945  130.109 1.00 356.14 ? 396 LYS A CG  1 
ATOM   1846  C CD  . LYS A 1 397 ? 124.210 75.941  129.437 1.00 439.47 ? 396 LYS A CD  1 
ATOM   1847  C CE  . LYS A 1 397 ? 125.331 75.527  130.368 1.00 490.30 ? 396 LYS A CE  1 
ATOM   1848  N NZ  . LYS A 1 397 ? 125.645 76.581  131.363 1.00 487.14 ? 396 LYS A NZ  1 
ATOM   1849  N N   . ASP A 1 398 ? 118.431 75.401  128.583 1.00 163.68 ? 397 ASP A N   1 
ATOM   1850  C CA  . ASP A 1 398 ? 117.130 75.503  127.930 1.00 225.15 ? 397 ASP A CA  1 
ATOM   1851  C C   . ASP A 1 398 ? 116.032 74.853  128.789 1.00 180.28 ? 397 ASP A C   1 
ATOM   1852  O O   . ASP A 1 398 ? 115.213 74.074  128.317 1.00 158.10 ? 397 ASP A O   1 
ATOM   1853  C CB  . ASP A 1 398 ? 117.251 74.961  126.503 1.00 324.98 ? 397 ASP A CB  1 
ATOM   1854  C CG  . ASP A 1 398 ? 116.122 75.358  125.562 1.00 470.43 ? 397 ASP A CG  1 
ATOM   1855  O OD1 . ASP A 1 398 ? 115.268 76.183  125.957 1.00 512.08 ? 397 ASP A OD1 1 
ATOM   1856  O OD2 . ASP A 1 398 ? 116.103 74.826  124.434 1.00 534.70 ? 397 ASP A OD2 1 
ATOM   1857  N N   . LEU A 1 399 ? 116.022 75.231  130.069 1.00 143.38 ? 398 LEU A N   1 
ATOM   1858  C CA  . LEU A 1 399 ? 114.947 74.973  131.004 1.00 91.69  ? 398 LEU A CA  1 
ATOM   1859  C C   . LEU A 1 399 ? 114.113 76.224  131.200 1.00 106.19 ? 398 LEU A C   1 
ATOM   1860  O O   . LEU A 1 399 ? 114.704 77.258  131.526 1.00 144.80 ? 398 LEU A O   1 
ATOM   1861  C CB  . LEU A 1 399 ? 115.627 74.734  132.321 1.00 81.91  ? 398 LEU A CB  1 
ATOM   1862  C CG  . LEU A 1 399 ? 114.753 74.195  133.451 1.00 95.05  ? 398 LEU A CG  1 
ATOM   1863  C CD1 . LEU A 1 399 ? 114.607 72.647  133.376 1.00 97.14  ? 398 LEU A CD1 1 
ATOM   1864  C CD2 . LEU A 1 399 ? 115.329 74.641  134.785 1.00 104.23 ? 398 LEU A CD2 1 
ATOM   1865  N N   . LEU A 1 400 ? 112.779 76.177  131.013 1.00 86.67  ? 399 LEU A N   1 
ATOM   1866  C CA  . LEU A 1 400 ? 111.981 77.256  131.562 1.00 84.49  ? 399 LEU A CA  1 
ATOM   1867  C C   . LEU A 1 400 ? 111.812 77.007  133.024 1.00 83.46  ? 399 LEU A C   1 
ATOM   1868  O O   . LEU A 1 400 ? 111.437 75.883  133.358 1.00 69.91  ? 399 LEU A O   1 
ATOM   1869  C CB  . LEU A 1 400 ? 110.593 77.291  130.953 1.00 74.61  ? 399 LEU A CB  1 
ATOM   1870  C CG  . LEU A 1 400 ? 110.562 77.506  129.457 1.00 78.41  ? 399 LEU A CG  1 
ATOM   1871  C CD1 . LEU A 1 400 ? 109.198 78.051  129.089 1.00 72.49  ? 399 LEU A CD1 1 
ATOM   1872  C CD2 . LEU A 1 400 ? 111.661 78.424  128.942 1.00 131.15 ? 399 LEU A CD2 1 
ATOM   1873  N N   . LEU A 1 401 ? 112.046 78.042  133.845 1.00 63.98  ? 400 LEU A N   1 
ATOM   1874  C CA  . LEU A 1 401 ? 111.907 77.819  135.269 1.00 74.69  ? 400 LEU A CA  1 
ATOM   1875  C C   . LEU A 1 401 ? 110.981 78.912  135.776 1.00 85.35  ? 400 LEU A C   1 
ATOM   1876  O O   . LEU A 1 401 ? 111.383 80.073  135.966 1.00 117.14 ? 400 LEU A O   1 
ATOM   1877  C CB  . LEU A 1 401 ? 113.294 77.836  135.906 1.00 70.96  ? 400 LEU A CB  1 
ATOM   1878  C CG  . LEU A 1 401 ? 113.326 77.991  137.400 1.00 88.74  ? 400 LEU A CG  1 
ATOM   1879  C CD1 . LEU A 1 401 ? 112.627 76.823  138.021 1.00 102.76 ? 400 LEU A CD1 1 
ATOM   1880  C CD2 . LEU A 1 401 ? 114.745 78.035  137.847 1.00 121.96 ? 400 LEU A CD2 1 
ATOM   1881  N N   . THR A 1 402 ? 109.725 78.514  135.980 1.00 54.71  ? 401 THR A N   1 
ATOM   1882  C CA  . THR A 1 402 ? 108.748 79.361  136.605 1.00 73.19  ? 401 THR A CA  1 
ATOM   1883  C C   . THR A 1 402 ? 109.002 79.408  138.108 1.00 87.65  ? 401 THR A C   1 
ATOM   1884  O O   . THR A 1 402 ? 109.534 78.471  138.669 1.00 101.30 ? 401 THR A O   1 
ATOM   1885  C CB  . THR A 1 402 ? 107.340 78.854  136.321 1.00 85.19  ? 401 THR A CB  1 
ATOM   1886  O OG1 . THR A 1 402 ? 107.171 77.537  136.880 1.00 47.19  ? 401 THR A OG1 1 
ATOM   1887  C CG2 . THR A 1 402 ? 107.082 78.987  134.817 1.00 88.97  ? 401 THR A CG2 1 
ATOM   1888  N N   . SER A 1 403 ? 108.639 80.534  138.733 1.00 91.99  ? 402 SER A N   1 
ATOM   1889  C CA  . SER A 1 403 ? 109.011 80.804  140.100 1.00 68.70  ? 402 SER A CA  1 
ATOM   1890  C C   . SER A 1 403 ? 108.106 81.864  140.673 1.00 78.63  ? 402 SER A C   1 
ATOM   1891  O O   . SER A 1 403 ? 107.280 82.468  139.962 1.00 131.15 ? 402 SER A O   1 
ATOM   1892  C CB  . SER A 1 403 ? 110.388 81.307  140.141 1.00 81.04  ? 402 SER A CB  1 
ATOM   1893  O OG  . SER A 1 403 ? 110.485 82.592  139.515 1.00 69.85  ? 402 SER A OG  1 
ATOM   1894  N N   . SER A 1 404 ? 108.288 82.101  141.962 1.00 63.59  ? 403 SER A N   1 
ATOM   1895  C CA  . SER A 1 404 ? 107.585 83.191  142.580 1.00 77.49  ? 403 SER A CA  1 
ATOM   1896  C C   . SER A 1 404 ? 108.382 84.491  142.393 1.00 63.78  ? 403 SER A C   1 
ATOM   1897  O O   . SER A 1 404 ? 108.073 85.499  143.043 1.00 92.84  ? 403 SER A O   1 
ATOM   1898  C CB  . SER A 1 404 ? 107.304 82.880  144.044 1.00 115.81 ? 403 SER A CB  1 
ATOM   1899  O OG  . SER A 1 404 ? 106.625 81.633  144.232 1.00 104.79 ? 403 SER A OG  1 
ATOM   1900  N N   . TYR A 1 405 ? 109.371 84.566  141.523 1.00 49.01  ? 404 TYR A N   1 
ATOM   1901  C CA  . TYR A 1 405 ? 110.252 85.732  141.601 1.00 65.80  ? 404 TYR A CA  1 
ATOM   1902  C C   . TYR A 1 405 ? 109.613 87.105  141.368 1.00 63.19  ? 404 TYR A C   1 
ATOM   1903  O O   . TYR A 1 405 ? 109.905 88.005  142.170 1.00 61.73  ? 404 TYR A O   1 
ATOM   1904  C CB  . TYR A 1 405 ? 111.388 85.566  140.604 1.00 71.75  ? 404 TYR A CB  1 
ATOM   1905  C CG  . TYR A 1 405 ? 112.286 86.765  140.485 1.00 52.43  ? 404 TYR A CG  1 
ATOM   1906  C CD1 . TYR A 1 405 ? 113.070 87.192  141.501 1.00 96.80  ? 404 TYR A CD1 1 
ATOM   1907  C CD2 . TYR A 1 405 ? 112.274 87.493  139.348 1.00 68.37  ? 404 TYR A CD2 1 
ATOM   1908  C CE1 . TYR A 1 405 ? 113.880 88.300  141.339 1.00 137.73 ? 404 TYR A CE1 1 
ATOM   1909  C CE2 . TYR A 1 405 ? 113.067 88.586  139.157 1.00 75.53  ? 404 TYR A CE2 1 
ATOM   1910  C CZ  . TYR A 1 405 ? 113.894 88.995  140.148 1.00 90.38  ? 404 TYR A CZ  1 
ATOM   1911  O OH  . TYR A 1 405 ? 114.639 90.090  139.895 1.00 79.22  ? 404 TYR A OH  1 
ATOM   1912  N N   . LEU A 1 406 ? 108.781 87.251  140.312 1.00 48.98  ? 405 LEU A N   1 
ATOM   1913  C CA  . LEU A 1 406 ? 107.993 88.467  140.215 1.00 53.11  ? 405 LEU A CA  1 
ATOM   1914  C C   . LEU A 1 406 ? 106.801 88.641  141.205 1.00 67.92  ? 405 LEU A C   1 
ATOM   1915  O O   . LEU A 1 406 ? 106.108 89.680  141.137 1.00 86.10  ? 405 LEU A O   1 
ATOM   1916  C CB  . LEU A 1 406 ? 107.407 88.529  138.826 1.00 58.61  ? 405 LEU A CB  1 
ATOM   1917  C CG  . LEU A 1 406 ? 108.242 88.990  137.683 1.00 68.20  ? 405 LEU A CG  1 
ATOM   1918  C CD1 . LEU A 1 406 ? 107.324 89.570  136.619 1.00 66.25  ? 405 LEU A CD1 1 
ATOM   1919  C CD2 . LEU A 1 406 ? 109.177 90.037  138.127 1.00 83.79  ? 405 LEU A CD2 1 
ATOM   1920  N N   . SER A 1 407 ? 106.514 87.700  142.116 1.00 66.51  ? 406 SER A N   1 
ATOM   1921  C CA  . SER A 1 407 ? 105.314 87.697  142.926 1.00 90.24  ? 406 SER A CA  1 
ATOM   1922  C C   . SER A 1 407 ? 105.323 88.836  143.952 1.00 142.45 ? 406 SER A C   1 
ATOM   1923  O O   . SER A 1 407 ? 104.275 89.435  144.226 1.00 124.46 ? 406 SER A O   1 
ATOM   1924  C CB  . SER A 1 407 ? 105.260 86.360  143.629 1.00 128.65 ? 406 SER A CB  1 
ATOM   1925  O OG  . SER A 1 407 ? 104.196 86.235  144.536 1.00 182.98 ? 406 SER A OG  1 
ATOM   1926  N N   . ASP A 1 408 ? 106.515 89.113  144.518 1.00 174.37 ? 407 ASP A N   1 
ATOM   1927  C CA  . ASP A 1 408 ? 106.722 90.047  145.627 1.00 208.57 ? 407 ASP A CA  1 
ATOM   1928  C C   . ASP A 1 408 ? 106.796 91.496  145.114 1.00 161.73 ? 407 ASP A C   1 
ATOM   1929  O O   . ASP A 1 408 ? 107.744 92.239  145.391 1.00 202.90 ? 407 ASP A O   1 
ATOM   1930  C CB  . ASP A 1 408 ? 107.988 89.658  146.418 1.00 317.53 ? 407 ASP A CB  1 
ATOM   1931  C CG  . ASP A 1 408 ? 108.097 88.202  146.884 1.00 383.90 ? 407 ASP A CG  1 
ATOM   1932  O OD1 . ASP A 1 408 ? 107.046 87.643  147.272 1.00 375.58 ? 407 ASP A OD1 1 
ATOM   1933  O OD2 . ASP A 1 408 ? 109.235 87.630  146.869 1.00 447.08 ? 407 ASP A OD2 1 
ATOM   1934  N N   . SER A 1 409 ? 105.770 91.920  144.369 1.00 173.13 ? 408 SER A N   1 
ATOM   1935  C CA  . SER A 1 409 ? 105.805 93.085  143.480 1.00 171.09 ? 408 SER A CA  1 
ATOM   1936  C C   . SER A 1 409 ? 105.739 94.439  144.186 1.00 165.86 ? 408 SER A C   1 
ATOM   1937  O O   . SER A 1 409 ? 105.823 95.447  143.506 1.00 110.15 ? 408 SER A O   1 
ATOM   1938  C CB  . SER A 1 409 ? 104.638 93.012  142.540 1.00 227.05 ? 408 SER A CB  1 
ATOM   1939  O OG  . SER A 1 409 ? 103.397 93.144  143.257 1.00 234.34 ? 408 SER A OG  1 
ATOM   1940  N N   . GLY A 1 410 ? 105.570 94.498  145.518 1.00 215.13 ? 409 GLY A N   1 
ATOM   1941  C CA  . GLY A 1 410 ? 105.351 95.777  146.193 1.00 241.87 ? 409 GLY A CA  1 
ATOM   1942  C C   . GLY A 1 410 ? 103.891 96.247  146.249 1.00 213.36 ? 409 GLY A C   1 
ATOM   1943  O O   . GLY A 1 410 ? 103.607 97.235  146.940 1.00 172.84 ? 409 GLY A O   1 
ATOM   1944  N N   . SER A 1 411 ? 102.974 95.558  145.546 1.00 199.00 ? 410 SER A N   1 
ATOM   1945  C CA  . SER A 1 411 ? 101.531 95.724  145.692 1.00 257.05 ? 410 SER A CA  1 
ATOM   1946  C C   . SER A 1 411 ? 101.020 97.172  145.489 1.00 177.46 ? 410 SER A C   1 
ATOM   1947  O O   . SER A 1 411 ? 99.865  97.483  145.833 1.00 168.02 ? 410 SER A O   1 
ATOM   1948  C CB  . SER A 1 411 ? 101.077 95.126  147.010 1.00 357.62 ? 410 SER A CB  1 
ATOM   1949  O OG  . SER A 1 411 ? 101.403 93.741  147.056 1.00 378.80 ? 410 SER A OG  1 
ATOM   1950  N N   . THR A 1 412 ? 101.839 98.058  144.898 1.00 139.57 ? 411 THR A N   1 
ATOM   1951  C CA  . THR A 1 412 ? 101.366 98.991  143.867 1.00 163.87 ? 411 THR A CA  1 
ATOM   1952  C C   . THR A 1 412 ? 102.401 99.014  142.745 1.00 122.86 ? 411 THR A C   1 
ATOM   1953  O O   . THR A 1 412 ? 102.835 100.054 142.289 1.00 163.50 ? 411 THR A O   1 
ATOM   1954  C CB  . THR A 1 412 ? 101.048 100.334 144.523 1.00 229.57 ? 411 THR A CB  1 
ATOM   1955  O OG1 . THR A 1 412 ? 99.854  100.118 145.274 1.00 319.62 ? 411 THR A OG1 1 
ATOM   1956  C CG2 . THR A 1 412 ? 100.816 101.476 143.564 1.00 193.00 ? 411 THR A CG2 1 
ATOM   1957  N N   . GLY A 1 413 ? 102.856 97.824  142.331 1.00 123.09 ? 412 GLY A N   1 
ATOM   1958  C CA  . GLY A 1 413 ? 103.720 97.640  141.186 1.00 99.93  ? 412 GLY A CA  1 
ATOM   1959  C C   . GLY A 1 413 ? 105.170 98.078  141.375 1.00 95.02  ? 412 GLY A C   1 
ATOM   1960  O O   . GLY A 1 413 ? 106.016 97.783  140.520 1.00 129.86 ? 412 GLY A O   1 
ATOM   1961  N N   . GLU A 1 414 ? 105.478 98.765  142.482 1.00 97.11  ? 413 GLU A N   1 
ATOM   1962  C CA  . GLU A 1 414 ? 106.543 99.762  142.500 1.00 102.05 ? 413 GLU A CA  1 
ATOM   1963  C C   . GLU A 1 414 ? 107.900 99.144  142.178 1.00 110.34 ? 413 GLU A C   1 
ATOM   1964  O O   . GLU A 1 414 ? 108.727 99.815  141.535 1.00 145.08 ? 413 GLU A O   1 
ATOM   1965  C CB  . GLU A 1 414 ? 106.473 100.509 143.833 1.00 154.22 ? 413 GLU A CB  1 
ATOM   1966  C CG  . GLU A 1 414 ? 106.829 99.717  145.099 1.00 182.86 ? 413 GLU A CG  1 
ATOM   1967  C CD  . GLU A 1 414 ? 106.316 100.337 146.402 1.00 280.49 ? 413 GLU A CD  1 
ATOM   1968  O OE1 . GLU A 1 414 ? 105.275 101.041 146.373 1.00 309.85 ? 413 GLU A OE1 1 
ATOM   1969  O OE2 . GLU A 1 414 ? 106.946 100.125 147.465 1.00 312.05 ? 413 GLU A OE2 1 
ATOM   1970  N N   . HIS A 1 415 ? 108.093 97.882  142.606 1.00 104.88 ? 414 HIS A N   1 
ATOM   1971  C CA  . HIS A 1 415 ? 109.334 97.150  142.435 1.00 112.08 ? 414 HIS A CA  1 
ATOM   1972  C C   . HIS A 1 415 ? 109.539 96.566  141.048 1.00 84.07  ? 414 HIS A C   1 
ATOM   1973  O O   . HIS A 1 415 ? 110.671 96.292  140.677 1.00 119.57 ? 414 HIS A O   1 
ATOM   1974  C CB  . HIS A 1 415 ? 109.391 96.008  143.440 1.00 135.07 ? 414 HIS A CB  1 
ATOM   1975  C CG  . HIS A 1 415 ? 109.610 96.505  144.808 1.00 164.21 ? 414 HIS A CG  1 
ATOM   1976  N ND1 . HIS A 1 415 ? 109.144 95.852  145.931 1.00 219.96 ? 414 HIS A ND1 1 
ATOM   1977  C CD2 . HIS A 1 415 ? 110.243 97.619  145.200 1.00 143.64 ? 414 HIS A CD2 1 
ATOM   1978  C CE1 . HIS A 1 415 ? 109.502 96.570  146.984 1.00 258.80 ? 414 HIS A CE1 1 
ATOM   1979  N NE2 . HIS A 1 415 ? 110.170 97.635  146.559 1.00 235.03 ? 414 HIS A NE2 1 
ATOM   1980  N N   . THR A 1 416 ? 108.497 96.408  140.272 1.00 90.07  ? 415 THR A N   1 
ATOM   1981  C CA  . THR A 1 416 ? 108.588 95.612  139.064 1.00 71.34  ? 415 THR A CA  1 
ATOM   1982  C C   . THR A 1 416 ? 109.610 96.071  138.033 1.00 68.14  ? 415 THR A C   1 
ATOM   1983  O O   . THR A 1 416 ? 110.239 95.204  137.448 1.00 68.97  ? 415 THR A O   1 
ATOM   1984  C CB  . THR A 1 416 ? 107.197 95.533  138.426 1.00 69.62  ? 415 THR A CB  1 
ATOM   1985  O OG1 . THR A 1 416 ? 106.548 94.708  139.377 1.00 110.38 ? 415 THR A OG1 1 
ATOM   1986  C CG2 . THR A 1 416 ? 107.170 94.775  137.142 1.00 97.65  ? 415 THR A CG2 1 
ATOM   1987  N N   . LYS A 1 417 ? 109.772 97.379  137.751 1.00 85.66  ? 416 LYS A N   1 
ATOM   1988  C CA  . LYS A 1 417 ? 110.763 97.805  136.763 1.00 66.70  ? 416 LYS A CA  1 
ATOM   1989  C C   . LYS A 1 417 ? 112.085 97.157  137.096 1.00 94.05  ? 416 LYS A C   1 
ATOM   1990  O O   . LYS A 1 417 ? 112.866 96.902  136.185 1.00 103.30 ? 416 LYS A O   1 
ATOM   1991  C CB  . LYS A 1 417 ? 110.985 99.327  136.721 1.00 116.87 ? 416 LYS A CB  1 
ATOM   1992  C CG  . LYS A 1 417 ? 112.081 99.855  135.774 1.00 120.95 ? 416 LYS A CG  1 
ATOM   1993  C CD  . LYS A 1 417 ? 112.179 101.326 135.596 1.00 181.05 ? 416 LYS A CD  1 
ATOM   1994  C CE  . LYS A 1 417 ? 113.570 101.761 135.166 1.00 255.16 ? 416 LYS A CE  1 
ATOM   1995  N NZ  . LYS A 1 417 ? 113.737 103.241 135.248 1.00 392.30 ? 416 LYS A NZ  1 
ATOM   1996  N N   . SER A 1 418 ? 112.313 96.948  138.413 1.00 96.23  ? 417 SER A N   1 
ATOM   1997  C CA  . SER A 1 418 ? 113.620 96.620  138.905 1.00 91.75  ? 417 SER A CA  1 
ATOM   1998  C C   . SER A 1 418 ? 113.693 95.112  138.977 1.00 67.15  ? 417 SER A C   1 
ATOM   1999  O O   . SER A 1 418 ? 114.746 94.586  138.620 1.00 106.71 ? 417 SER A O   1 
ATOM   2000  C CB  . SER A 1 418 ? 113.915 97.373  140.208 1.00 112.31 ? 417 SER A CB  1 
ATOM   2001  O OG  . SER A 1 418 ? 113.308 96.748  141.333 1.00 148.79 ? 417 SER A OG  1 
ATOM   2002  N N   . LEU A 1 419 ? 112.638 94.418  139.455 1.00 66.98  ? 418 LEU A N   1 
ATOM   2003  C CA  . LEU A 1 419 ? 112.698 92.965  139.494 1.00 68.62  ? 418 LEU A CA  1 
ATOM   2004  C C   . LEU A 1 419 ? 112.941 92.449  138.094 1.00 60.85  ? 418 LEU A C   1 
ATOM   2005  O O   . LEU A 1 419 ? 113.716 91.512  137.941 1.00 65.08  ? 418 LEU A O   1 
ATOM   2006  C CB  . LEU A 1 419 ? 111.445 92.309  140.029 1.00 44.08  ? 418 LEU A CB  1 
ATOM   2007  C CG  . LEU A 1 419 ? 111.224 92.505  141.482 1.00 64.43  ? 418 LEU A CG  1 
ATOM   2008  C CD1 . LEU A 1 419 ? 109.823 92.058  141.917 1.00 127.49 ? 418 LEU A CD1 1 
ATOM   2009  C CD2 . LEU A 1 419 ? 112.296 91.791  142.269 1.00 144.38 ? 418 LEU A CD2 1 
ATOM   2010  N N   . VAL A 1 420 ? 112.269 93.025  137.113 1.00 47.72  ? 419 VAL A N   1 
ATOM   2011  C CA  . VAL A 1 420 ? 112.376 92.524  135.766 1.00 50.74  ? 419 VAL A CA  1 
ATOM   2012  C C   . VAL A 1 420 ? 113.722 92.837  135.178 1.00 59.89  ? 419 VAL A C   1 
ATOM   2013  O O   . VAL A 1 420 ? 114.308 91.943  134.612 1.00 63.56  ? 419 VAL A O   1 
ATOM   2014  C CB  . VAL A 1 420 ? 111.294 93.085  134.871 1.00 47.55  ? 419 VAL A CB  1 
ATOM   2015  C CG1 . VAL A 1 420 ? 111.631 92.865  133.422 1.00 45.85  ? 419 VAL A CG1 1 
ATOM   2016  C CG2 . VAL A 1 420 ? 109.975 92.469  135.247 1.00 55.10  ? 419 VAL A CG2 1 
ATOM   2017  N N   . THR A 1 421 ? 114.214 94.063  135.280 1.00 69.46  ? 420 THR A N   1 
ATOM   2018  C CA  . THR A 1 421 ? 115.440 94.342  134.576 1.00 82.33  ? 420 THR A CA  1 
ATOM   2019  C C   . THR A 1 421 ? 116.658 93.813  135.309 1.00 99.47  ? 420 THR A C   1 
ATOM   2020  O O   . THR A 1 421 ? 117.678 93.717  134.631 1.00 114.74 ? 420 THR A O   1 
ATOM   2021  C CB  . THR A 1 421 ? 115.640 95.836  134.363 1.00 99.19  ? 420 THR A CB  1 
ATOM   2022  O OG1 . THR A 1 421 ? 115.581 96.635  135.541 1.00 112.32 ? 420 THR A OG1 1 
ATOM   2023  C CG2 . THR A 1 421 ? 114.561 96.338  133.466 1.00 125.67 ? 420 THR A CG2 1 
ATOM   2024  N N   . GLN A 1 422 ? 116.606 93.531  136.628 1.00 83.97  ? 421 GLN A N   1 
ATOM   2025  C CA  . GLN A 1 422 ? 117.699 92.812  137.251 1.00 98.52  ? 421 GLN A CA  1 
ATOM   2026  C C   . GLN A 1 422 ? 117.707 91.401  136.699 1.00 76.92  ? 421 GLN A C   1 
ATOM   2027  O O   . GLN A 1 422 ? 118.775 90.882  136.418 1.00 118.03 ? 421 GLN A O   1 
ATOM   2028  C CB  . GLN A 1 422 ? 117.611 92.745  138.764 1.00 127.15 ? 421 GLN A CB  1 
ATOM   2029  C CG  . GLN A 1 422 ? 118.038 94.018  139.464 1.00 144.36 ? 421 GLN A CG  1 
ATOM   2030  C CD  . GLN A 1 422 ? 117.664 93.957  140.940 1.00 251.53 ? 421 GLN A CD  1 
ATOM   2031  O OE1 . GLN A 1 422 ? 117.154 92.955  141.462 1.00 216.40 ? 421 GLN A OE1 1 
ATOM   2032  N NE2 . GLN A 1 422 ? 117.913 95.053  141.643 1.00 326.45 ? 421 GLN A NE2 1 
ATOM   2033  N N   . TYR A 1 423 ? 116.567 90.761  136.549 1.00 61.34  ? 422 TYR A N   1 
ATOM   2034  C CA  . TYR A 1 423 ? 116.602 89.355  136.169 1.00 76.52  ? 422 TYR A CA  1 
ATOM   2035  C C   . TYR A 1 423 ? 117.090 89.143  134.754 1.00 68.98  ? 422 TYR A C   1 
ATOM   2036  O O   . TYR A 1 423 ? 117.906 88.290  134.521 1.00 96.19  ? 422 TYR A O   1 
ATOM   2037  C CB  . TYR A 1 423 ? 115.216 88.807  136.306 1.00 69.16  ? 422 TYR A CB  1 
ATOM   2038  C CG  . TYR A 1 423 ? 115.087 87.330  136.082 1.00 67.67  ? 422 TYR A CG  1 
ATOM   2039  C CD1 . TYR A 1 423 ? 115.104 86.804  134.855 1.00 76.00  ? 422 TYR A CD1 1 
ATOM   2040  C CD2 . TYR A 1 423 ? 114.902 86.484  137.128 1.00 133.82 ? 422 TYR A CD2 1 
ATOM   2041  C CE1 . TYR A 1 423 ? 114.939 85.454  134.628 1.00 133.77 ? 422 TYR A CE1 1 
ATOM   2042  C CE2 . TYR A 1 423 ? 114.740 85.127  136.941 1.00 169.97 ? 422 TYR A CE2 1 
ATOM   2043  C CZ  . TYR A 1 423 ? 114.764 84.598  135.678 1.00 116.11 ? 422 TYR A CZ  1 
ATOM   2044  O OH  . TYR A 1 423 ? 114.607 83.256  135.511 1.00 132.57 ? 422 TYR A OH  1 
ATOM   2045  N N   . LEU A 1 424 ? 116.611 89.923  133.830 1.00 65.93  ? 423 LEU A N   1 
ATOM   2046  C CA  . LEU A 1 424 ? 117.163 89.929  132.494 1.00 61.10  ? 423 LEU A CA  1 
ATOM   2047  C C   . LEU A 1 424 ? 118.665 90.141  132.533 1.00 87.77  ? 423 LEU A C   1 
ATOM   2048  O O   . LEU A 1 424 ? 119.375 89.372  131.893 1.00 138.30 ? 423 LEU A O   1 
ATOM   2049  C CB  . LEU A 1 424 ? 116.498 91.029  131.673 1.00 79.30  ? 423 LEU A CB  1 
ATOM   2050  C CG  . LEU A 1 424 ? 115.093 90.638  131.200 1.00 73.45  ? 423 LEU A CG  1 
ATOM   2051  C CD1 . LEU A 1 424 ? 114.273 91.736  130.438 1.00 69.68  ? 423 LEU A CD1 1 
ATOM   2052  C CD2 . LEU A 1 424 ? 115.218 89.441  130.312 1.00 69.59  ? 423 LEU A CD2 1 
ATOM   2053  N N   . ASN A 1 425 ? 119.163 91.149  133.239 1.00 97.90  ? 424 ASN A N   1 
ATOM   2054  C CA  . ASN A 1 425 ? 120.597 91.434  133.319 1.00 136.80 ? 424 ASN A CA  1 
ATOM   2055  C C   . ASN A 1 425 ? 121.376 90.270  133.899 1.00 84.84  ? 424 ASN A C   1 
ATOM   2056  O O   . ASN A 1 425 ? 122.364 89.837  133.318 1.00 121.31 ? 424 ASN A O   1 
ATOM   2057  C CB  . ASN A 1 425 ? 120.867 92.673  134.155 1.00 181.32 ? 424 ASN A CB  1 
ATOM   2058  C CG  . ASN A 1 425 ? 122.256 93.268  133.989 1.00 204.23 ? 424 ASN A CG  1 
ATOM   2059  O OD1 . ASN A 1 425 ? 122.834 93.323  132.895 1.00 155.57 ? 424 ASN A OD1 1 
ATOM   2060  N ND2 . ASN A 1 425 ? 122.792 93.737  135.104 1.00 294.12 ? 424 ASN A ND2 1 
ATOM   2061  N N   . ALA A 1 426 ? 120.897 89.730  135.002 1.00 93.60  ? 425 ALA A N   1 
ATOM   2062  C CA  . ALA A 1 426 ? 121.557 88.601  135.652 1.00 139.02 ? 425 ALA A CA  1 
ATOM   2063  C C   . ALA A 1 426 ? 121.649 87.337  134.782 1.00 108.57 ? 425 ALA A C   1 
ATOM   2064  O O   . ALA A 1 426 ? 122.711 86.709  134.740 1.00 135.11 ? 425 ALA A O   1 
ATOM   2065  C CB  . ALA A 1 426 ? 120.864 88.327  136.953 1.00 145.72 ? 425 ALA A CB  1 
ATOM   2066  N N   . THR A 1 427 ? 120.573 86.970  134.082 1.00 85.68  ? 426 THR A N   1 
ATOM   2067  C CA  . THR A 1 427 ? 120.585 85.823  133.178 1.00 130.70 ? 426 THR A CA  1 
ATOM   2068  C C   . THR A 1 427 ? 121.301 86.110  131.858 1.00 111.80 ? 426 THR A C   1 
ATOM   2069  O O   . THR A 1 427 ? 121.599 85.176  131.108 1.00 147.58 ? 426 THR A O   1 
ATOM   2070  C CB  . THR A 1 427 ? 119.179 85.270  132.857 1.00 159.55 ? 426 THR A CB  1 
ATOM   2071  O OG1 . THR A 1 427 ? 118.400 86.295  132.260 1.00 116.53 ? 426 THR A OG1 1 
ATOM   2072  C CG2 . THR A 1 427 ? 118.478 84.701  134.076 1.00 166.91 ? 426 THR A CG2 1 
ATOM   2073  N N   . GLY A 1 428 ? 121.592 87.370  131.559 1.00 114.25 ? 427 GLY A N   1 
ATOM   2074  C CA  . GLY A 1 428 ? 122.298 87.708  130.328 1.00 171.02 ? 427 GLY A CA  1 
ATOM   2075  C C   . GLY A 1 428 ? 121.400 87.648  129.089 1.00 126.58 ? 427 GLY A C   1 
ATOM   2076  O O   . GLY A 1 428 ? 121.853 87.313  127.992 1.00 154.70 ? 427 GLY A O   1 
ATOM   2077  N N   . ASN A 1 429 ? 120.132 87.987  129.291 1.00 117.09 ? 428 ASN A N   1 
ATOM   2078  C CA  . ASN A 1 429 ? 119.132 88.067  128.237 1.00 123.00 ? 428 ASN A CA  1 
ATOM   2079  C C   . ASN A 1 429 ? 118.954 86.738  127.510 1.00 136.28 ? 428 ASN A C   1 
ATOM   2080  O O   . ASN A 1 429 ? 118.703 86.746  126.314 1.00 174.03 ? 428 ASN A O   1 
ATOM   2081  C CB  . ASN A 1 429 ? 119.461 89.291  127.376 1.00 139.86 ? 428 ASN A CB  1 
ATOM   2082  C CG  . ASN A 1 429 ? 119.091 90.629  128.018 1.00 210.17 ? 428 ASN A CG  1 
ATOM   2083  O OD1 . ASN A 1 429 ? 119.370 90.876  129.199 1.00 169.57 ? 428 ASN A OD1 1 
ATOM   2084  N ND2 . ASN A 1 429 ? 118.449 91.518  127.263 1.00 254.51 ? 428 ASN A ND2 1 
ATOM   2085  N N   . ARG A 1 430 ? 119.051 85.600  128.228 1.00 137.99 ? 429 ARG A N   1 
ATOM   2086  C CA  . ARG A 1 430 ? 118.641 84.305  127.680 1.00 140.41 ? 429 ARG A CA  1 
ATOM   2087  C C   . ARG A 1 430 ? 117.108 84.272  127.530 1.00 159.42 ? 429 ARG A C   1 
ATOM   2088  O O   . ARG A 1 430 ? 116.387 85.266  127.716 1.00 154.80 ? 429 ARG A O   1 
ATOM   2089  C CB  . ARG A 1 430 ? 119.215 83.168  128.538 1.00 137.57 ? 429 ARG A CB  1 
ATOM   2090  C CG  . ARG A 1 430 ? 120.707 82.903  128.357 1.00 182.80 ? 429 ARG A CG  1 
ATOM   2091  C CD  . ARG A 1 430 ? 121.204 81.771  129.254 1.00 259.24 ? 429 ARG A CD  1 
ATOM   2092  N NE  . ARG A 1 430 ? 121.406 82.176  130.647 1.00 260.98 ? 429 ARG A NE  1 
ATOM   2093  C CZ  . ARG A 1 430 ? 121.590 81.376  131.718 1.00 241.54 ? 429 ARG A CZ  1 
ATOM   2094  N NH1 . ARG A 1 430 ? 121.912 81.944  132.870 1.00 236.07 ? 429 ARG A NH1 1 
ATOM   2095  N NH2 . ARG A 1 430 ? 121.472 80.046  131.693 1.00 215.69 ? 429 ARG A NH2 1 
ATOM   2096  N N   . TRP A 1 431 ? 116.568 83.101  127.192 1.00 144.14 ? 430 TRP A N   1 
ATOM   2097  C CA  . TRP A 1 431 ? 115.122 82.886  127.305 1.00 94.24  ? 430 TRP A CA  1 
ATOM   2098  C C   . TRP A 1 431 ? 114.657 82.717  128.749 1.00 90.48  ? 430 TRP A C   1 
ATOM   2099  O O   . TRP A 1 431 ? 115.390 82.251  129.637 1.00 178.86 ? 430 TRP A O   1 
ATOM   2100  C CB  . TRP A 1 431 ? 114.703 81.671  126.474 1.00 113.12 ? 430 TRP A CB  1 
ATOM   2101  C CG  . TRP A 1 431 ? 113.371 81.968  125.885 1.00 92.76  ? 430 TRP A CG  1 
ATOM   2102  C CD1 . TRP A 1 431 ? 112.233 81.335  126.208 1.00 98.78  ? 430 TRP A CD1 1 
ATOM   2103  C CD2 . TRP A 1 431 ? 113.018 82.985  124.921 1.00 93.55  ? 430 TRP A CD2 1 
ATOM   2104  N NE1 . TRP A 1 431 ? 111.177 81.875  125.514 1.00 65.10  ? 430 TRP A NE1 1 
ATOM   2105  C CE2 . TRP A 1 431 ? 111.633 82.882  124.725 1.00 64.90  ? 430 TRP A CE2 1 
ATOM   2106  C CE3 . TRP A 1 431 ? 113.728 83.965  124.225 1.00 156.60 ? 430 TRP A CE3 1 
ATOM   2107  C CZ2 . TRP A 1 431 ? 110.944 83.719  123.883 1.00 66.30  ? 430 TRP A CZ2 1 
ATOM   2108  C CZ3 . TRP A 1 431 ? 113.055 84.789  123.364 1.00 165.48 ? 430 TRP A CZ3 1 
ATOM   2109  C CH2 . TRP A 1 431 ? 111.680 84.668  123.209 1.00 117.96 ? 430 TRP A CH2 1 
ATOM   2110  N N   . CYS A 1 432 ? 113.432 83.155  129.006 1.00 80.49  ? 431 CYS A N   1 
ATOM   2111  C CA  . CYS A 1 432 ? 112.843 83.206  130.344 1.00 94.32  ? 431 CYS A CA  1 
ATOM   2112  C C   . CYS A 1 432 ? 111.402 82.712  130.279 1.00 69.20  ? 431 CYS A C   1 
ATOM   2113  O O   . CYS A 1 432 ? 110.807 82.606  129.226 1.00 87.13  ? 431 CYS A O   1 
ATOM   2114  C CB  . CYS A 1 432 ? 112.822 84.635  130.854 1.00 79.89  ? 431 CYS A CB  1 
ATOM   2115  S SG  . CYS A 1 432 ? 114.439 85.407  130.646 1.00 251.22 ? 431 CYS A SG  1 
ATOM   2116  N N   . SER A 1 433 ? 110.806 82.432  131.385 1.00 58.70  ? 432 SER A N   1 
ATOM   2117  C CA  . SER A 1 433 ? 109.381 82.280  131.406 1.00 75.25  ? 432 SER A CA  1 
ATOM   2118  C C   . SER A 1 433 ? 108.720 83.207  132.446 1.00 74.34  ? 432 SER A C   1 
ATOM   2119  O O   . SER A 1 433 ? 108.739 82.911  133.624 1.00 70.40  ? 432 SER A O   1 
ATOM   2120  C CB  . SER A 1 433 ? 109.066 80.831  131.711 1.00 118.80 ? 432 SER A CB  1 
ATOM   2121  O OG  . SER A 1 433 ? 109.653 80.352  132.899 1.00 84.24  ? 432 SER A OG  1 
ATOM   2122  N N   . TRP A 1 434 ? 108.101 84.272  131.992 1.00 52.56  ? 433 TRP A N   1 
ATOM   2123  C CA  . TRP A 1 434 ? 107.484 85.146  132.925 1.00 57.71  ? 433 TRP A CA  1 
ATOM   2124  C C   . TRP A 1 434 ? 106.200 84.596  133.507 1.00 59.49  ? 433 TRP A C   1 
ATOM   2125  O O   . TRP A 1 434 ? 105.369 84.106  132.763 1.00 68.93  ? 433 TRP A O   1 
ATOM   2126  C CB  . TRP A 1 434 ? 107.245 86.448  132.181 1.00 68.09  ? 433 TRP A CB  1 
ATOM   2127  C CG  . TRP A 1 434 ? 108.574 87.015  131.778 1.00 64.40  ? 433 TRP A CG  1 
ATOM   2128  C CD1 . TRP A 1 434 ? 109.012 87.022  130.520 1.00 76.78  ? 433 TRP A CD1 1 
ATOM   2129  C CD2 . TRP A 1 434 ? 109.596 87.634  132.596 1.00 68.66  ? 433 TRP A CD2 1 
ATOM   2130  N NE1 . TRP A 1 434 ? 110.242 87.609  130.503 1.00 101.84 ? 433 TRP A NE1 1 
ATOM   2131  C CE2 . TRP A 1 434 ? 110.612 87.980  131.747 1.00 61.92  ? 433 TRP A CE2 1 
ATOM   2132  C CE3 . TRP A 1 434 ? 109.736 87.939  133.952 1.00 98.60  ? 433 TRP A CE3 1 
ATOM   2133  C CZ2 . TRP A 1 434 ? 111.748 88.591  132.183 1.00 92.98  ? 433 TRP A CZ2 1 
ATOM   2134  C CZ3 . TRP A 1 434 ? 110.866 88.553  134.390 1.00 83.71  ? 433 TRP A CZ3 1 
ATOM   2135  C CH2 . TRP A 1 434 ? 111.853 88.882  133.512 1.00 107.55 ? 433 TRP A CH2 1 
ATOM   2136  N N   . SER A 1 435 ? 106.063 84.707  134.818 1.00 62.68  ? 434 SER A N   1 
ATOM   2137  C CA  . SER A 1 435 ? 104.945 84.110  135.497 1.00 71.22  ? 434 SER A CA  1 
ATOM   2138  C C   . SER A 1 435 ? 104.875 84.660  136.887 1.00 71.94  ? 434 SER A C   1 
ATOM   2139  O O   . SER A 1 435 ? 105.949 84.757  137.494 1.00 108.63 ? 434 SER A O   1 
ATOM   2140  C CB  . SER A 1 435 ? 105.148 82.623  135.616 1.00 68.75  ? 434 SER A CB  1 
ATOM   2141  O OG  . SER A 1 435 ? 106.395 82.314  136.253 1.00 98.06  ? 434 SER A OG  1 
ATOM   2142  N N   . LEU A 1 436 ? 103.684 84.948  137.425 1.00 61.78  ? 435 LEU A N   1 
ATOM   2143  C CA  . LEU A 1 436 ? 103.697 85.283  138.842 1.00 67.36  ? 435 LEU A CA  1 
ATOM   2144  C C   . LEU A 1 436 ? 103.797 84.056  139.724 1.00 68.38  ? 435 LEU A C   1 
ATOM   2145  O O   . LEU A 1 436 ? 104.138 84.277  140.902 1.00 127.38 ? 435 LEU A O   1 
ATOM   2146  C CB  . LEU A 1 436 ? 102.557 86.214  139.257 1.00 61.43  ? 435 LEU A CB  1 
ATOM   2147  C CG  . LEU A 1 436 ? 102.497 87.515  138.453 1.00 79.58  ? 435 LEU A CG  1 
ATOM   2148  C CD1 . LEU A 1 436 ? 101.509 88.456  139.088 1.00 153.26 ? 435 LEU A CD1 1 
ATOM   2149  C CD2 . LEU A 1 436 ? 103.815 88.218  138.353 1.00 97.93  ? 435 LEU A CD2 1 
ATOM   2150  N N   . SER A 1 437 ? 103.562 82.830  139.236 1.00 57.79  ? 436 SER A N   1 
ATOM   2151  C CA  . SER A 1 437 ? 103.896 81.693  140.084 1.00 71.68  ? 436 SER A CA  1 
ATOM   2152  C C   . SER A 1 437 ? 104.127 80.421  139.295 1.00 72.75  ? 436 SER A C   1 
ATOM   2153  O O   . SER A 1 437 ? 103.732 80.346  138.145 1.00 161.28 ? 436 SER A O   1 
ATOM   2154  C CB  . SER A 1 437 ? 102.788 81.522  141.137 1.00 98.51  ? 436 SER A CB  1 
ATOM   2155  O OG  . SER A 1 437 ? 102.991 80.401  142.001 1.00 120.48 ? 436 SER A OG  1 
ATOM   2156  N N   . GLN A 1 438 ? 104.708 79.405  139.935 1.00 76.98  ? 437 GLN A N   1 
ATOM   2157  C CA  . GLN A 1 438 ? 104.614 78.021  139.474 1.00 77.88  ? 437 GLN A CA  1 
ATOM   2158  C C   . GLN A 1 438 ? 103.203 77.415  139.388 1.00 80.63  ? 437 GLN A C   1 
ATOM   2159  O O   . GLN A 1 438 ? 103.037 76.455  138.610 1.00 129.88 ? 437 GLN A O   1 
ATOM   2160  C CB  . GLN A 1 438 ? 105.447 77.112  140.367 1.00 101.87 ? 437 GLN A CB  1 
ATOM   2161  C CG  . GLN A 1 438 ? 105.081 77.099  141.841 1.00 108.91 ? 437 GLN A CG  1 
ATOM   2162  C CD  . GLN A 1 438 ? 105.844 75.987  142.494 1.00 135.82 ? 437 GLN A CD  1 
ATOM   2163  O OE1 . GLN A 1 438 ? 106.806 75.444  141.954 1.00 83.95  ? 437 GLN A OE1 1 
ATOM   2164  N NE2 . GLN A 1 438 ? 105.384 75.641  143.682 1.00 196.30 ? 437 GLN A NE2 1 
ATOM   2165  N N   . ALA A 1 439 ? 102.191 77.917  140.122 1.00 73.31  ? 438 ALA A N   1 
ATOM   2166  C CA  . ALA A 1 439 ? 100.858 77.347  140.008 1.00 124.17 ? 438 ALA A CA  1 
ATOM   2167  C C   . ALA A 1 439 ? 99.722  78.358  140.177 1.00 108.22 ? 438 ALA A C   1 
ATOM   2168  O O   . ALA A 1 439 ? 98.786  78.337  139.394 1.00 113.75 ? 438 ALA A O   1 
ATOM   2169  C CB  . ALA A 1 439 ? 100.736 76.230  141.014 1.00 158.46 ? 438 ALA A CB  1 
ATOM   2170  N N   . ARG A 1 440 ? 99.753  79.196  141.212 1.00 91.13  ? 439 ARG A N   1 
ATOM   2171  C CA  . ARG A 1 440 ? 98.583  79.963  141.601 1.00 111.01 ? 439 ARG A CA  1 
ATOM   2172  C C   . ARG A 1 440 ? 98.265  81.072  140.582 1.00 104.88 ? 439 ARG A C   1 
ATOM   2173  O O   . ARG A 1 440 ? 99.109  81.487  139.786 1.00 105.21 ? 439 ARG A O   1 
ATOM   2174  C CB  . ARG A 1 440 ? 98.842  80.498  143.009 1.00 138.97 ? 439 ARG A CB  1 
ATOM   2175  C CG  . ARG A 1 440 ? 98.803  79.432  144.094 1.00 143.51 ? 439 ARG A CG  1 
ATOM   2176  C CD  . ARG A 1 440 ? 99.475  79.936  145.359 1.00 192.82 ? 439 ARG A CD  1 
ATOM   2177  N NE  . ARG A 1 440 ? 98.936  81.183  145.914 1.00 233.04 ? 439 ARG A NE  1 
ATOM   2178  C CZ  . ARG A 1 440 ? 99.521  81.891  146.886 1.00 285.71 ? 439 ARG A CZ  1 
ATOM   2179  N NH1 . ARG A 1 440 ? 99.028  83.059  147.268 1.00 316.09 ? 439 ARG A NH1 1 
ATOM   2180  N NH2 . ARG A 1 440 ? 100.614 81.438  147.478 1.00 313.45 ? 439 ARG A NH2 1 
ATOM   2181  N N   . LEU A 1 441 ? 97.014  81.576  140.589 1.00 105.67 ? 440 LEU A N   1 
ATOM   2182  C CA  . LEU A 1 441 ? 96.525  82.611  139.659 1.00 99.49  ? 440 LEU A CA  1 
ATOM   2183  C C   . LEU A 1 441 ? 97.235  83.955  139.782 1.00 91.44  ? 440 LEU A C   1 
ATOM   2184  O O   . LEU A 1 441 ? 97.758  84.220  140.862 1.00 136.29 ? 440 LEU A O   1 
ATOM   2185  C CB  . LEU A 1 441 ? 95.063  82.848  140.013 1.00 113.06 ? 440 LEU A CB  1 
ATOM   2186  C CG  . LEU A 1 441 ? 94.122  81.681  139.806 1.00 117.17 ? 440 LEU A CG  1 
ATOM   2187  C CD1 . LEU A 1 441 ? 92.830  82.044  140.501 1.00 200.60 ? 440 LEU A CD1 1 
ATOM   2188  C CD2 . LEU A 1 441 ? 93.900  81.485  138.327 1.00 139.37 ? 440 LEU A CD2 1 
ATOM   2189  N N   . LEU A 1 442 ? 97.232  84.829  138.751 1.00 79.57  ? 441 LEU A N   1 
ATOM   2190  C CA  . LEU A 1 442 ? 97.682  86.221  138.955 1.00 82.84  ? 441 LEU A CA  1 
ATOM   2191  C C   . LEU A 1 442 ? 96.991  86.889  140.120 1.00 85.18  ? 441 LEU A C   1 
ATOM   2192  O O   . LEU A 1 442 ? 97.651  87.509  140.940 1.00 109.76 ? 441 LEU A O   1 
ATOM   2193  C CB  . LEU A 1 442 ? 97.407  87.186  137.818 1.00 64.37  ? 441 LEU A CB  1 
ATOM   2194  C CG  . LEU A 1 442 ? 98.110  86.890  136.507 1.00 101.06 ? 441 LEU A CG  1 
ATOM   2195  C CD1 . LEU A 1 442 ? 97.847  87.997  135.484 1.00 96.01  ? 441 LEU A CD1 1 
ATOM   2196  C CD2 . LEU A 1 442 ? 99.589  86.869  136.693 1.00 84.61  ? 441 LEU A CD2 1 
ATOM   2197  N N   . THR A 1 443 ? 95.674  86.720  140.185 1.00 85.03  ? 442 THR A N   1 
ATOM   2198  C CA  . THR A 1 443 ? 94.900  87.387  141.222 1.00 77.99  ? 442 THR A CA  1 
ATOM   2199  C C   . THR A 1 443 ? 95.175  86.823  142.630 1.00 92.74  ? 442 THR A C   1 
ATOM   2200  O O   . THR A 1 443 ? 94.650  87.355  143.608 1.00 115.57 ? 442 THR A O   1 
ATOM   2201  C CB  . THR A 1 443 ? 93.414  87.361  140.870 1.00 116.23 ? 442 THR A CB  1 
ATOM   2202  O OG1 . THR A 1 443 ? 93.200  87.312  139.457 1.00 107.26 ? 442 THR A OG1 1 
ATOM   2203  C CG2 . THR A 1 443 ? 92.706  88.573  141.439 1.00 210.37 ? 442 THR A CG2 1 
ATOM   2204  N N   . SER A 1 444 ? 96.008  85.783  142.771 1.00 94.78  ? 443 SER A N   1 
ATOM   2205  C CA  . SER A 1 444 ? 96.523  85.396  144.076 1.00 129.28 ? 443 SER A CA  1 
ATOM   2206  C C   . SER A 1 444 ? 97.511  86.409  144.663 1.00 103.21 ? 443 SER A C   1 
ATOM   2207  O O   . SER A 1 444 ? 97.797  86.337  145.861 1.00 135.54 ? 443 SER A O   1 
ATOM   2208  C CB  . SER A 1 444 ? 97.123  84.013  144.028 1.00 148.03 ? 443 SER A CB  1 
ATOM   2209  O OG  . SER A 1 444 ? 97.011  83.371  145.291 1.00 236.49 ? 443 SER A OG  1 
ATOM   2210  N N   . PHE A 1 445 ? 98.029  87.329  143.842 1.00 97.43  ? 444 PHE A N   1 
ATOM   2211  C CA  . PHE A 1 445 ? 99.131  88.201  144.218 1.00 110.87 ? 444 PHE A CA  1 
ATOM   2212  C C   . PHE A 1 445 ? 98.835  89.652  143.879 1.00 112.90 ? 444 PHE A C   1 
ATOM   2213  O O   . PHE A 1 445 ? 99.016  90.551  144.698 1.00 164.29 ? 444 PHE A O   1 
ATOM   2214  C CB  . PHE A 1 445 ? 100.419 87.814  143.498 1.00 114.53 ? 444 PHE A CB  1 
ATOM   2215  C CG  . PHE A 1 445 ? 100.754 86.352  143.648 1.00 111.50 ? 444 PHE A CG  1 
ATOM   2216  C CD1 . PHE A 1 445 ? 101.258 85.832  144.833 1.00 132.23 ? 444 PHE A CD1 1 
ATOM   2217  C CD2 . PHE A 1 445 ? 100.546 85.503  142.596 1.00 97.08  ? 444 PHE A CD2 1 
ATOM   2218  C CE1 . PHE A 1 445 ? 101.561 84.490  144.948 1.00 142.31 ? 444 PHE A CE1 1 
ATOM   2219  C CE2 . PHE A 1 445 ? 100.851 84.157  142.709 1.00 148.82 ? 444 PHE A CE2 1 
ATOM   2220  C CZ  . PHE A 1 445 ? 101.356 83.649  143.884 1.00 164.47 ? 444 PHE A CZ  1 
ATOM   2221  N N   . LEU A 1 446 ? 98.377  89.885  142.664 1.00 90.10  ? 445 LEU A N   1 
ATOM   2222  C CA  . LEU A 1 446 ? 97.999  91.222  142.259 1.00 106.65 ? 445 LEU A CA  1 
ATOM   2223  C C   . LEU A 1 446 ? 96.665  91.718  142.835 1.00 127.76 ? 445 LEU A C   1 
ATOM   2224  O O   . LEU A 1 446 ? 95.661  91.003  142.928 1.00 133.54 ? 445 LEU A O   1 
ATOM   2225  C CB  . LEU A 1 446 ? 97.919  91.230  140.729 1.00 95.84  ? 445 LEU A CB  1 
ATOM   2226  C CG  . LEU A 1 446 ? 99.268  91.055  140.057 1.00 94.31  ? 445 LEU A CG  1 
ATOM   2227  C CD1 . LEU A 1 446 ? 99.146  91.389  138.628 1.00 83.96  ? 445 LEU A CD1 1 
ATOM   2228  C CD2 . LEU A 1 446 ? 100.373 91.887  140.699 1.00 103.70 ? 445 LEU A CD2 1 
ATOM   2229  N N   . PRO A 1 447 ? 96.613  93.017  143.207 1.00 99.85  ? 446 PRO A N   1 
ATOM   2230  C CA  . PRO A 1 447 ? 95.340  93.675  143.433 1.00 134.51 ? 446 PRO A CA  1 
ATOM   2231  C C   . PRO A 1 447 ? 94.758  94.040  142.078 1.00 111.61 ? 446 PRO A C   1 
ATOM   2232  O O   . PRO A 1 447 ? 95.501  94.374  141.166 1.00 120.40 ? 446 PRO A O   1 
ATOM   2233  C CB  . PRO A 1 447 ? 95.766  94.889  144.289 1.00 200.24 ? 446 PRO A CB  1 
ATOM   2234  C CG  . PRO A 1 447 ? 97.171  95.256  143.791 1.00 140.32 ? 446 PRO A CG  1 
ATOM   2235  C CD  . PRO A 1 447 ? 97.764  93.914  143.441 1.00 123.94 ? 446 PRO A CD  1 
ATOM   2236  N N   . ALA A 1 448 ? 93.429  94.033  141.978 1.00 106.14 ? 447 ALA A N   1 
ATOM   2237  C CA  . ALA A 1 448 ? 92.756  93.948  140.701 1.00 117.85 ? 447 ALA A CA  1 
ATOM   2238  C C   . ALA A 1 448 ? 92.954  95.150  139.757 1.00 102.77 ? 447 ALA A C   1 
ATOM   2239  O O   . ALA A 1 448 ? 92.608  95.027  138.579 1.00 115.25 ? 447 ALA A O   1 
ATOM   2240  C CB  . ALA A 1 448 ? 91.287  93.714  140.992 1.00 194.66 ? 447 ALA A CB  1 
ATOM   2241  N N   . GLN A 1 449 ? 93.467  96.308  140.218 1.00 124.02 ? 448 GLN A N   1 
ATOM   2242  C CA  . GLN A 1 449 ? 93.770  97.420  139.315 1.00 157.69 ? 448 GLN A CA  1 
ATOM   2243  C C   . GLN A 1 449 ? 94.994  97.165  138.428 1.00 104.84 ? 448 GLN A C   1 
ATOM   2244  O O   . GLN A 1 449 ? 95.125  97.752  137.340 1.00 134.59 ? 448 GLN A O   1 
ATOM   2245  C CB  . GLN A 1 449 ? 93.928  98.753  140.064 1.00 189.89 ? 448 GLN A CB  1 
ATOM   2246  C CG  . GLN A 1 449 ? 95.208  98.986  140.863 1.00 147.36 ? 448 GLN A CG  1 
ATOM   2247  C CD  . GLN A 1 449 ? 95.047  98.517  142.288 1.00 198.64 ? 448 GLN A CD  1 
ATOM   2248  O OE1 . GLN A 1 449 ? 94.273  97.602  142.574 1.00 212.05 ? 448 GLN A OE1 1 
ATOM   2249  N NE2 . GLN A 1 449 ? 95.785  99.132  143.206 1.00 255.33 ? 448 GLN A NE2 1 
ATOM   2250  N N   . LEU A 1 450 ? 95.876  96.301  138.895 1.00 93.47  ? 449 LEU A N   1 
ATOM   2251  C CA  . LEU A 1 450 ? 97.055  95.959  138.140 1.00 89.53  ? 449 LEU A CA  1 
ATOM   2252  C C   . LEU A 1 450 ? 96.857  94.795  137.178 1.00 84.18  ? 449 LEU A C   1 
ATOM   2253  O O   . LEU A 1 450 ? 97.719  94.648  136.336 1.00 82.79  ? 449 LEU A O   1 
ATOM   2254  C CB  . LEU A 1 450 ? 98.135  95.537  139.131 1.00 66.04  ? 449 LEU A CB  1 
ATOM   2255  C CG  . LEU A 1 450 ? 98.629  96.602  140.074 1.00 91.09  ? 449 LEU A CG  1 
ATOM   2256  C CD1 . LEU A 1 450 ? 99.885  96.022  140.687 1.00 95.37  ? 449 LEU A CD1 1 
ATOM   2257  C CD2 . LEU A 1 450 ? 98.950  97.963  139.412 1.00 108.06 ? 449 LEU A CD2 1 
ATOM   2258  N N   . LEU A 1 451 ? 95.820  93.956  137.295 1.00 72.63  ? 450 LEU A N   1 
ATOM   2259  C CA  . LEU A 1 451 ? 95.722  92.815  136.419 1.00 66.80  ? 450 LEU A CA  1 
ATOM   2260  C C   . LEU A 1 451 ? 95.848  93.266  134.959 1.00 81.50  ? 450 LEU A C   1 
ATOM   2261  O O   . LEU A 1 451 ? 96.567  92.578  134.214 1.00 65.24  ? 450 LEU A O   1 
ATOM   2262  C CB  . LEU A 1 451 ? 94.408  92.084  136.594 1.00 62.48  ? 450 LEU A CB  1 
ATOM   2263  C CG  . LEU A 1 451 ? 94.342  91.268  137.844 1.00 78.49  ? 450 LEU A CG  1 
ATOM   2264  C CD1 . LEU A 1 451 ? 92.892  90.900  138.140 1.00 161.11 ? 450 LEU A CD1 1 
ATOM   2265  C CD2 . LEU A 1 451 ? 95.083  90.012  137.659 1.00 116.27 ? 450 LEU A CD2 1 
ATOM   2266  N N   . ARG A 1 452 ? 95.196  94.371  134.525 1.00 64.67  ? 451 ARG A N   1 
ATOM   2267  C CA  . ARG A 1 452 ? 95.367  94.698  133.117 1.00 68.45  ? 451 ARG A CA  1 
ATOM   2268  C C   . ARG A 1 452 ? 96.799  95.104  132.776 1.00 66.82  ? 451 ARG A C   1 
ATOM   2269  O O   . ARG A 1 452 ? 97.356  94.786  131.716 1.00 52.37  ? 451 ARG A O   1 
ATOM   2270  C CB  . ARG A 1 452 ? 94.413  95.786  132.703 1.00 99.21  ? 451 ARG A CB  1 
ATOM   2271  C CG  . ARG A 1 452 ? 92.970  95.332  132.727 1.00 142.60 ? 451 ARG A CG  1 
ATOM   2272  C CD  . ARG A 1 452 ? 92.191  96.498  132.216 1.00 127.05 ? 451 ARG A CD  1 
ATOM   2273  N NE  . ARG A 1 452 ? 90.833  96.132  132.362 1.00 138.45 ? 451 ARG A NE  1 
ATOM   2274  C CZ  . ARG A 1 452 ? 90.082  95.863  131.334 1.00 200.21 ? 451 ARG A CZ  1 
ATOM   2275  N NH1 . ARG A 1 452 ? 88.798  95.661  131.579 1.00 286.58 ? 451 ARG A NH1 1 
ATOM   2276  N NH2 . ARG A 1 452 ? 90.625  95.830  130.112 1.00 119.18 ? 451 ARG A NH2 1 
ATOM   2277  N N   . LEU A 1 453 ? 97.390  95.806  133.728 1.00 76.29  ? 452 LEU A N   1 
ATOM   2278  C CA  . LEU A 1 453 ? 98.721  96.323  133.531 1.00 59.94  ? 452 LEU A CA  1 
ATOM   2279  C C   . LEU A 1 453 ? 99.752  95.212  133.474 1.00 61.13  ? 452 LEU A C   1 
ATOM   2280  O O   . LEU A 1 453 ? 100.713 95.402  132.792 1.00 55.05  ? 452 LEU A O   1 
ATOM   2281  C CB  . LEU A 1 453 ? 99.025  97.205  134.735 1.00 54.23  ? 452 LEU A CB  1 
ATOM   2282  C CG  . LEU A 1 453 ? 100.200 98.143  134.564 1.00 62.84  ? 452 LEU A CG  1 
ATOM   2283  C CD1 . LEU A 1 453 ? 100.103 98.939  133.314 1.00 62.01  ? 452 LEU A CD1 1 
ATOM   2284  C CD2 . LEU A 1 453 ? 100.169 99.132  135.678 1.00 106.28 ? 452 LEU A CD2 1 
ATOM   2285  N N   . TYR A 1 454 ? 99.562  94.108  134.208 1.00 55.14  ? 453 TYR A N   1 
ATOM   2286  C CA  . TYR A 1 454 ? 100.497 93.027  134.157 1.00 63.92  ? 453 TYR A CA  1 
ATOM   2287  C C   . TYR A 1 454 ? 100.243 92.192  132.907 1.00 76.20  ? 453 TYR A C   1 
ATOM   2288  O O   . TYR A 1 454 ? 101.185 91.711  132.299 1.00 88.11  ? 453 TYR A O   1 
ATOM   2289  C CB  . TYR A 1 454 ? 100.394 92.066  135.307 1.00 77.26  ? 453 TYR A CB  1 
ATOM   2290  C CG  . TYR A 1 454 ? 101.424 92.411  136.354 1.00 65.34  ? 453 TYR A CG  1 
ATOM   2291  C CD1 . TYR A 1 454 ? 101.339 93.519  137.079 1.00 63.41  ? 453 TYR A CD1 1 
ATOM   2292  C CD2 . TYR A 1 454 ? 102.438 91.569  136.601 1.00 91.39  ? 453 TYR A CD2 1 
ATOM   2293  C CE1 . TYR A 1 454 ? 102.255 93.810  138.042 1.00 76.06  ? 453 TYR A CE1 1 
ATOM   2294  C CE2 . TYR A 1 454 ? 103.384 91.851  137.551 1.00 112.86 ? 453 TYR A CE2 1 
ATOM   2295  C CZ  . TYR A 1 454 ? 103.285 92.971  138.288 1.00 88.84  ? 453 TYR A CZ  1 
ATOM   2296  O OH  . TYR A 1 454 ? 104.275 93.167  139.204 1.00 132.19 ? 453 TYR A OH  1 
ATOM   2297  N N   . GLN A 1 455 ? 99.015  92.030  132.474 1.00 66.17  ? 454 GLN A N   1 
ATOM   2298  C CA  . GLN A 1 455 ? 98.857  91.280  131.242 1.00 75.73  ? 454 GLN A CA  1 
ATOM   2299  C C   . GLN A 1 455 ? 99.496  92.018  130.085 1.00 64.67  ? 454 GLN A C   1 
ATOM   2300  O O   . GLN A 1 455 ? 99.811  91.360  129.115 1.00 83.79  ? 454 GLN A O   1 
ATOM   2301  C CB  . GLN A 1 455 ? 97.376  90.969  130.911 1.00 84.43  ? 454 GLN A CB  1 
ATOM   2302  C CG  . GLN A 1 455 ? 97.005  89.879  131.863 1.00 105.10 ? 454 GLN A CG  1 
ATOM   2303  C CD  . GLN A 1 455 ? 95.615  89.415  131.716 1.00 137.31 ? 454 GLN A CD  1 
ATOM   2304  O OE1 . GLN A 1 455 ? 94.990  89.767  130.696 1.00 99.78  ? 454 GLN A OE1 1 
ATOM   2305  N NE2 . GLN A 1 455 ? 95.217  88.632  132.733 1.00 135.45 ? 454 GLN A NE2 1 
ATOM   2306  N N   . LEU A 1 456 ? 99.599  93.353  130.138 1.00 49.18  ? 455 LEU A N   1 
ATOM   2307  C CA  . LEU A 1 456 ? 100.223 94.056  129.058 1.00 49.68  ? 455 LEU A CA  1 
ATOM   2308  C C   . LEU A 1 456 ? 101.715 93.804  129.126 1.00 50.32  ? 455 LEU A C   1 
ATOM   2309  O O   . LEU A 1 456 ? 102.379 93.904  128.106 1.00 64.42  ? 455 LEU A O   1 
ATOM   2310  C CB  . LEU A 1 456 ? 99.842  95.514  129.082 1.00 56.64  ? 455 LEU A CB  1 
ATOM   2311  C CG  . LEU A 1 456 ? 100.647 96.425  128.143 1.00 72.43  ? 455 LEU A CG  1 
ATOM   2312  C CD1 . LEU A 1 456 ? 100.628 95.996  126.723 1.00 70.56  ? 455 LEU A CD1 1 
ATOM   2313  C CD2 . LEU A 1 456 ? 100.071 97.819  128.213 1.00 111.11 ? 455 LEU A CD2 1 
ATOM   2314  N N   . MET A 1 457 ? 102.234 93.502  130.295 1.00 42.85  ? 456 MET A N   1 
ATOM   2315  C CA  . MET A 1 457 ? 103.664 93.391  130.464 1.00 50.14  ? 456 MET A CA  1 
ATOM   2316  C C   . MET A 1 457 ? 104.057 91.926  130.215 1.00 64.76  ? 456 MET A C   1 
ATOM   2317  O O   . MET A 1 457 ? 104.966 91.695  129.471 1.00 95.20  ? 456 MET A O   1 
ATOM   2318  C CB  . MET A 1 457 ? 104.050 93.895  131.863 1.00 45.96  ? 456 MET A CB  1 
ATOM   2319  C CG  . MET A 1 457 ? 105.492 93.679  132.162 1.00 63.40  ? 456 MET A CG  1 
ATOM   2320  S SD  . MET A 1 457 ? 106.003 93.898  133.828 1.00 65.40  ? 456 MET A SD  1 
ATOM   2321  C CE  . MET A 1 457 ? 105.539 92.334  134.549 1.00 41.62  ? 456 MET A CE  1 
ATOM   2322  N N   . LEU A 1 458 ? 103.402 90.950  130.824 1.00 53.92  ? 457 LEU A N   1 
ATOM   2323  C CA  . LEU A 1 458 ? 103.665 89.564  130.605 1.00 49.44  ? 457 LEU A CA  1 
ATOM   2324  C C   . LEU A 1 458 ? 103.552 89.160  129.124 1.00 66.44  ? 457 LEU A C   1 
ATOM   2325  O O   . LEU A 1 458 ? 104.231 88.250  128.637 1.00 82.37  ? 457 LEU A O   1 
ATOM   2326  C CB  . LEU A 1 458 ? 102.721 88.792  131.536 1.00 53.62  ? 457 LEU A CB  1 
ATOM   2327  C CG  . LEU A 1 458 ? 103.445 88.107  132.689 1.00 67.12  ? 457 LEU A CG  1 
ATOM   2328  C CD1 . LEU A 1 458 ? 104.499 89.048  133.285 1.00 63.69  ? 457 LEU A CD1 1 
ATOM   2329  C CD2 . LEU A 1 458 ? 102.450 87.607  133.686 1.00 91.47  ? 457 LEU A CD2 1 
ATOM   2330  N N   . PHE A 1 459 ? 102.752 89.856  128.342 1.00 61.34  ? 458 PHE A N   1 
ATOM   2331  C CA  . PHE A 1 459 ? 102.749 89.531  126.928 1.00 65.73  ? 458 PHE A CA  1 
ATOM   2332  C C   . PHE A 1 459 ? 103.832 90.212  126.109 1.00 55.01  ? 458 PHE A C   1 
ATOM   2333  O O   . PHE A 1 459 ? 103.841 89.989  124.917 1.00 78.11  ? 458 PHE A O   1 
ATOM   2334  C CB  . PHE A 1 459 ? 101.353 89.795  126.378 1.00 65.31  ? 458 PHE A CB  1 
ATOM   2335  C CG  . PHE A 1 459 ? 100.505 88.547  126.462 1.00 59.08  ? 458 PHE A CG  1 
ATOM   2336  C CD1 . PHE A 1 459 ? 100.711 87.517  125.612 1.00 55.13  ? 458 PHE A CD1 1 
ATOM   2337  C CD2 . PHE A 1 459 ? 99.515  88.397  127.398 1.00 63.23  ? 458 PHE A CD2 1 
ATOM   2338  C CE1 . PHE A 1 459 ? 99.907  86.405  125.672 1.00 103.19 ? 458 PHE A CE1 1 
ATOM   2339  C CE2 . PHE A 1 459 ? 98.733  87.275  127.484 1.00 54.95  ? 458 PHE A CE2 1 
ATOM   2340  C CZ  . PHE A 1 459 ? 98.929  86.291  126.615 1.00 63.55  ? 458 PHE A CZ  1 
ATOM   2341  N N   . THR A 1 460 ? 104.705 91.018  126.690 1.00 66.64  ? 459 THR A N   1 
ATOM   2342  C CA  . THR A 1 460 ? 105.618 91.834  125.899 1.00 64.74  ? 459 THR A CA  1 
ATOM   2343  C C   . THR A 1 460 ? 107.053 91.909  126.427 1.00 58.62  ? 459 THR A C   1 
ATOM   2344  O O   . THR A 1 460 ? 107.865 92.562  125.783 1.00 71.14  ? 459 THR A O   1 
ATOM   2345  C CB  . THR A 1 460 ? 105.033 93.237  125.662 1.00 65.21  ? 459 THR A CB  1 
ATOM   2346  O OG1 . THR A 1 460 ? 105.175 93.944  126.853 1.00 55.23  ? 459 THR A OG1 1 
ATOM   2347  C CG2 . THR A 1 460 ? 103.580 93.306  125.290 1.00 73.99  ? 459 THR A CG2 1 
ATOM   2348  N N   . LEU A 1 461 ? 107.393 91.201  127.504 1.00 74.46  ? 460 LEU A N   1 
ATOM   2349  C CA  . LEU A 1 461 ? 108.788 90.932  127.836 1.00 76.57  ? 460 LEU A CA  1 
ATOM   2350  C C   . LEU A 1 461 ? 109.329 89.767  127.006 1.00 72.23  ? 460 LEU A C   1 
ATOM   2351  O O   . LEU A 1 461 ? 108.546 88.934  126.546 1.00 73.09  ? 460 LEU A O   1 
ATOM   2352  C CB  . LEU A 1 461 ? 108.930 90.610  129.315 1.00 69.78  ? 460 LEU A CB  1 
ATOM   2353  C CG  . LEU A 1 461 ? 108.407 91.715  130.210 1.00 71.38  ? 460 LEU A CG  1 
ATOM   2354  C CD1 . LEU A 1 461 ? 108.344 91.205  131.646 1.00 64.91  ? 460 LEU A CD1 1 
ATOM   2355  C CD2 . LEU A 1 461 ? 109.236 92.993  129.985 1.00 63.37  ? 460 LEU A CD2 1 
ATOM   2356  N N   . PRO A 1 462 ? 110.661 89.765  126.801 1.00 49.90  ? 461 PRO A N   1 
ATOM   2357  C CA  . PRO A 1 462 ? 111.348 88.655  126.153 1.00 65.09  ? 461 PRO A CA  1 
ATOM   2358  C C   . PRO A 1 462 ? 111.209 87.335  126.847 1.00 64.95  ? 461 PRO A C   1 
ATOM   2359  O O   . PRO A 1 462 ? 111.672 87.228  127.975 1.00 102.61 ? 461 PRO A O   1 
ATOM   2360  C CB  . PRO A 1 462 ? 112.818 89.031  126.398 1.00 103.22 ? 461 PRO A CB  1 
ATOM   2361  C CG  . PRO A 1 462 ? 112.824 90.541  126.591 1.00 60.06  ? 461 PRO A CG  1 
ATOM   2362  C CD  . PRO A 1 462 ? 111.534 90.886  127.205 1.00 37.94  ? 461 PRO A CD  1 
ATOM   2363  N N   . GLY A 1 463 ? 110.557 86.370  126.217 1.00 81.36  ? 462 GLY A N   1 
ATOM   2364  C CA  . GLY A 1 463 ? 110.272 85.106  126.893 1.00 69.00  ? 462 GLY A CA  1 
ATOM   2365  C C   . GLY A 1 463 ? 108.847 84.608  126.799 1.00 42.64  ? 462 GLY A C   1 
ATOM   2366  O O   . GLY A 1 463 ? 107.986 85.298  126.354 1.00 90.52  ? 462 GLY A O   1 
ATOM   2367  N N   . THR A 1 464 ? 108.638 83.429  127.261 1.00 41.31  ? 463 THR A N   1 
ATOM   2368  C CA  . THR A 1 464 ? 107.413 82.710  127.100 1.00 49.77  ? 463 THR A CA  1 
ATOM   2369  C C   . THR A 1 464 ? 106.498 82.921  128.281 1.00 42.53  ? 463 THR A C   1 
ATOM   2370  O O   . THR A 1 464 ? 106.709 82.292  129.279 1.00 53.68  ? 463 THR A O   1 
ATOM   2371  C CB  . THR A 1 464 ? 107.764 81.215  127.141 1.00 56.60  ? 463 THR A CB  1 
ATOM   2372  O OG1 . THR A 1 464 ? 108.503 81.037  125.919 1.00 77.86  ? 463 THR A OG1 1 
ATOM   2373  C CG2 . THR A 1 464 ? 106.553 80.309  127.321 1.00 41.77  ? 463 THR A CG2 1 
ATOM   2374  N N   . PRO A 1 465 ? 105.451 83.711  128.243 1.00 37.67  ? 464 PRO A N   1 
ATOM   2375  C CA  . PRO A 1 465 ? 104.638 83.883  129.423 1.00 46.64  ? 464 PRO A CA  1 
ATOM   2376  C C   . PRO A 1 465 ? 103.844 82.673  129.792 1.00 38.75  ? 464 PRO A C   1 
ATOM   2377  O O   . PRO A 1 465 ? 103.454 81.950  128.937 1.00 56.70  ? 464 PRO A O   1 
ATOM   2378  C CB  . PRO A 1 465 ? 103.627 85.007  129.035 1.00 57.82  ? 464 PRO A CB  1 
ATOM   2379  C CG  . PRO A 1 465 ? 103.544 84.894  127.580 1.00 62.93  ? 464 PRO A CG  1 
ATOM   2380  C CD  . PRO A 1 465 ? 104.949 84.456  127.112 1.00 45.67  ? 464 PRO A CD  1 
ATOM   2381  N N   . VAL A 1 466 ? 103.564 82.510  131.067 1.00 44.45  ? 465 VAL A N   1 
ATOM   2382  C CA  . VAL A 1 466 ? 102.749 81.418  131.544 1.00 54.40  ? 465 VAL A CA  1 
ATOM   2383  C C   . VAL A 1 466 ? 101.605 81.883  132.467 1.00 59.87  ? 465 VAL A C   1 
ATOM   2384  O O   . VAL A 1 466 ? 101.805 82.560  133.454 1.00 117.32 ? 465 VAL A O   1 
ATOM   2385  C CB  . VAL A 1 466 ? 103.649 80.439  132.261 1.00 49.57  ? 465 VAL A CB  1 
ATOM   2386  C CG1 . VAL A 1 466 ? 102.754 79.316  132.845 1.00 84.97  ? 465 VAL A CG1 1 
ATOM   2387  C CG2 . VAL A 1 466 ? 104.746 79.920  131.358 1.00 35.83  ? 465 VAL A CG2 1 
ATOM   2388  N N   . PHE A 1 467 ? 100.404 81.502  132.125 1.00 58.02  ? 466 PHE A N   1 
ATOM   2389  C CA  . PHE A 1 467 ? 99.227  81.807  132.886 1.00 57.86  ? 466 PHE A CA  1 
ATOM   2390  C C   . PHE A 1 467 ? 98.555  80.556  133.417 1.00 63.49  ? 466 PHE A C   1 
ATOM   2391  O O   . PHE A 1 467 ? 98.563  79.524  132.756 1.00 83.87  ? 466 PHE A O   1 
ATOM   2392  C CB  . PHE A 1 467 ? 98.270  82.467  131.912 1.00 57.50  ? 466 PHE A CB  1 
ATOM   2393  C CG  . PHE A 1 467 ? 98.850  83.705  131.355 1.00 62.20  ? 466 PHE A CG  1 
ATOM   2394  C CD1 . PHE A 1 467 ? 98.924  84.830  132.140 1.00 65.62  ? 466 PHE A CD1 1 
ATOM   2395  C CD2 . PHE A 1 467 ? 99.336  83.742  130.085 1.00 75.66  ? 466 PHE A CD2 1 
ATOM   2396  C CE1 . PHE A 1 467 ? 99.433  86.018  131.663 1.00 74.77  ? 466 PHE A CE1 1 
ATOM   2397  C CE2 . PHE A 1 467 ? 99.850  84.947  129.595 1.00 97.85  ? 466 PHE A CE2 1 
ATOM   2398  C CZ  . PHE A 1 467 ? 99.917  86.075  130.390 1.00 93.75  ? 466 PHE A CZ  1 
ATOM   2399  N N   . SER A 1 468 ? 97.926  80.668  134.590 1.00 55.25  ? 467 SER A N   1 
ATOM   2400  C CA  . SER A 1 468 ? 97.035  79.607  135.033 1.00 64.11  ? 467 SER A CA  1 
ATOM   2401  C C   . SER A 1 468 ? 95.650  79.890  134.517 1.00 53.92  ? 467 SER A C   1 
ATOM   2402  O O   . SER A 1 468 ? 95.369  80.977  134.034 1.00 67.20  ? 467 SER A O   1 
ATOM   2403  C CB  . SER A 1 468 ? 97.066  79.421  136.523 1.00 102.17 ? 467 SER A CB  1 
ATOM   2404  O OG  . SER A 1 468 ? 98.428  79.232  136.970 1.00 170.81 ? 467 SER A OG  1 
ATOM   2405  N N   . TYR A 1 469 ? 94.772  78.923  134.658 1.00 62.59  ? 468 TYR A N   1 
ATOM   2406  C CA  . TYR A 1 469 ? 93.523  79.022  133.919 1.00 68.79  ? 468 TYR A CA  1 
ATOM   2407  C C   . TYR A 1 469 ? 92.646  80.064  134.572 1.00 68.12  ? 468 TYR A C   1 
ATOM   2408  O O   . TYR A 1 469 ? 92.545  80.154  135.786 1.00 53.02  ? 468 TYR A O   1 
ATOM   2409  C CB  . TYR A 1 469 ? 92.693  77.751  133.865 1.00 84.45  ? 468 TYR A CB  1 
ATOM   2410  C CG  . TYR A 1 469 ? 92.271  77.199  135.206 1.00 66.80  ? 468 TYR A CG  1 
ATOM   2411  C CD1 . TYR A 1 469 ? 93.115  76.461  136.018 1.00 84.73  ? 468 TYR A CD1 1 
ATOM   2412  C CD2 . TYR A 1 469 ? 91.022  77.417  135.603 1.00 70.05  ? 468 TYR A CD2 1 
ATOM   2413  C CE1 . TYR A 1 469 ? 92.696  75.985  137.219 1.00 118.54 ? 468 TYR A CE1 1 
ATOM   2414  C CE2 . TYR A 1 469 ? 90.586  76.926  136.807 1.00 106.88 ? 468 TYR A CE2 1 
ATOM   2415  C CZ  . TYR A 1 469 ? 91.416  76.211  137.624 1.00 101.41 ? 468 TYR A CZ  1 
ATOM   2416  O OH  . TYR A 1 469 ? 90.986  75.724  138.822 1.00 138.77 ? 468 TYR A OH  1 
ATOM   2417  N N   . GLY A 1 470 ? 92.072  80.894  133.736 1.00 89.09  ? 469 GLY A N   1 
ATOM   2418  C CA  . GLY A 1 470 ? 91.235  81.931  134.270 1.00 82.54  ? 469 GLY A CA  1 
ATOM   2419  C C   . GLY A 1 470 ? 91.970  83.212  134.578 1.00 68.22  ? 469 GLY A C   1 
ATOM   2420  O O   . GLY A 1 470 ? 91.301  84.161  134.899 1.00 121.03 ? 469 GLY A O   1 
ATOM   2421  N N   . ASP A 1 471 ? 93.292  83.269  134.447 1.00 77.70  ? 470 ASP A N   1 
ATOM   2422  C CA  . ASP A 1 471 ? 94.014  84.536  134.439 1.00 89.40  ? 470 ASP A CA  1 
ATOM   2423  C C   . ASP A 1 471 ? 93.458  85.449  133.370 1.00 76.98  ? 470 ASP A C   1 
ATOM   2424  O O   . ASP A 1 471 ? 93.380  86.655  133.579 1.00 113.52 ? 470 ASP A O   1 
ATOM   2425  C CB  . ASP A 1 471 ? 95.509  84.333  134.267 1.00 83.97  ? 470 ASP A CB  1 
ATOM   2426  C CG  . ASP A 1 471 ? 96.125  83.770  135.568 1.00 193.84 ? 470 ASP A CG  1 
ATOM   2427  O OD1 . ASP A 1 471 ? 95.523  83.950  136.708 1.00 166.73 ? 470 ASP A OD1 1 
ATOM   2428  O OD2 . ASP A 1 471 ? 97.199  83.112  135.481 1.00 189.21 ? 470 ASP A OD2 1 
ATOM   2429  N N   . GLU A 1 472 ? 93.006  84.848  132.276 1.00 72.19  ? 471 GLU A N   1 
ATOM   2430  C CA  . GLU A 1 472 ? 92.563  85.590  131.105 1.00 79.08  ? 471 GLU A CA  1 
ATOM   2431  C C   . GLU A 1 472 ? 91.228  86.247  131.397 1.00 79.54  ? 471 GLU A C   1 
ATOM   2432  O O   . GLU A 1 472 ? 90.836  87.088  130.606 1.00 87.10  ? 471 GLU A O   1 
ATOM   2433  C CB  . GLU A 1 472 ? 92.600  84.707  129.838 1.00 75.24  ? 471 GLU A CB  1 
ATOM   2434  C CG  . GLU A 1 472 ? 91.500  83.655  129.830 1.00 84.13  ? 471 GLU A CG  1 
ATOM   2435  C CD  . GLU A 1 472 ? 91.600  82.418  130.703 1.00 126.13 ? 471 GLU A CD  1 
ATOM   2436  O OE1 . GLU A 1 472 ? 92.434  82.392  131.555 1.00 173.49 ? 471 GLU A OE1 1 
ATOM   2437  O OE2 . GLU A 1 472 ? 90.869  81.475  130.502 1.00 136.38 ? 471 GLU A OE2 1 
ATOM   2438  N N   . ILE A 1 473 ? 90.542  85.860  132.485 1.00 74.40  ? 472 ILE A N   1 
ATOM   2439  C CA  . ILE A 1 473 ? 89.293  86.507  132.872 1.00 94.24  ? 472 ILE A CA  1 
ATOM   2440  C C   . ILE A 1 473 ? 89.380  87.158  134.240 1.00 79.12  ? 472 ILE A C   1 
ATOM   2441  O O   . ILE A 1 473 ? 88.357  87.629  134.738 1.00 107.90 ? 472 ILE A O   1 
ATOM   2442  C CB  . ILE A 1 473 ? 88.122  85.512  132.868 1.00 72.76  ? 472 ILE A CB  1 
ATOM   2443  C CG1 . ILE A 1 473 ? 88.293  84.458  133.950 1.00 88.50  ? 472 ILE A CG1 1 
ATOM   2444  C CG2 . ILE A 1 473 ? 87.982  84.935  131.489 1.00 76.24  ? 472 ILE A CG2 1 
ATOM   2445  C CD1 . ILE A 1 473 ? 87.068  83.682  134.272 1.00 82.32  ? 472 ILE A CD1 1 
ATOM   2446  N N   . GLY A 1 474 ? 90.565  87.196  134.831 1.00 90.79  ? 473 GLY A N   1 
ATOM   2447  C CA  . GLY A 1 474 ? 90.712  87.739  136.164 1.00 128.80 ? 473 GLY A CA  1 
ATOM   2448  C C   . GLY A 1 474 ? 89.905  86.966  137.187 1.00 92.82  ? 473 GLY A C   1 
ATOM   2449  O O   . GLY A 1 474 ? 89.286  87.557  138.084 1.00 176.74 ? 473 GLY A O   1 
ATOM   2450  N N   . LEU A 1 475 ? 89.938  85.659  137.061 1.00 70.73  ? 474 LEU A N   1 
ATOM   2451  C CA  . LEU A 1 475 ? 89.307  84.829  138.061 1.00 110.90 ? 474 LEU A CA  1 
ATOM   2452  C C   . LEU A 1 475 ? 89.993  85.079  139.408 1.00 127.78 ? 474 LEU A C   1 
ATOM   2453  O O   . LEU A 1 475 ? 91.163  85.460  139.459 1.00 150.87 ? 474 LEU A O   1 
ATOM   2454  C CB  . LEU A 1 475 ? 89.414  83.383  137.585 1.00 97.59  ? 474 LEU A CB  1 
ATOM   2455  C CG  . LEU A 1 475 ? 88.954  82.267  138.515 1.00 107.80 ? 474 LEU A CG  1 
ATOM   2456  C CD1 . LEU A 1 475 ? 87.516  82.381  139.007 1.00 154.62 ? 474 LEU A CD1 1 
ATOM   2457  C CD2 . LEU A 1 475 ? 89.100  80.972  137.753 1.00 131.83 ? 474 LEU A CD2 1 
ATOM   2458  N N   . ASP A 1 476 ? 89.243  84.888  140.513 1.00 137.93 ? 475 ASP A N   1 
ATOM   2459  C CA  . ASP A 1 476 ? 89.754  85.119  141.847 1.00 135.59 ? 475 ASP A CA  1 
ATOM   2460  C C   . ASP A 1 476 ? 89.092  84.134  142.796 1.00 133.25 ? 475 ASP A C   1 
ATOM   2461  O O   . ASP A 1 476 ? 87.859  84.077  142.856 1.00 176.32 ? 475 ASP A O   1 
ATOM   2462  C CB  . ASP A 1 476 ? 89.501  86.562  142.275 1.00 179.85 ? 475 ASP A CB  1 
ATOM   2463  C CG  . ASP A 1 476 ? 89.941  86.891  143.707 1.00 296.02 ? 475 ASP A CG  1 
ATOM   2464  O OD1 . ASP A 1 476 ? 90.526  85.994  144.394 1.00 292.35 ? 475 ASP A OD1 1 
ATOM   2465  O OD2 . ASP A 1 476 ? 89.698  88.048  144.134 1.00 350.58 ? 475 ASP A OD2 1 
ATOM   2466  N N   . ALA A 1 477 ? 89.921  83.398  143.551 1.00 142.73 ? 476 ALA A N   1 
ATOM   2467  C CA  . ALA A 1 477 ? 89.401  82.348  144.410 1.00 171.82 ? 476 ALA A CA  1 
ATOM   2468  C C   . ALA A 1 477 ? 88.552  82.944  145.537 1.00 152.22 ? 476 ALA A C   1 
ATOM   2469  O O   . ALA A 1 477 ? 87.613  82.268  145.988 1.00 207.69 ? 476 ALA A O   1 
ATOM   2470  C CB  . ALA A 1 477 ? 90.519  81.483  144.935 1.00 204.30 ? 476 ALA A CB  1 
ATOM   2471  N N   . ALA A 1 478 ? 88.870  84.182  145.964 1.00 143.07 ? 477 ALA A N   1 
ATOM   2472  C CA  . ALA A 1 478 ? 88.182  84.822  147.087 1.00 225.57 ? 477 ALA A CA  1 
ATOM   2473  C C   . ALA A 1 478 ? 86.763  85.319  146.754 1.00 178.86 ? 477 ALA A C   1 
ATOM   2474  O O   . ALA A 1 478 ? 85.918  85.410  147.646 1.00 193.89 ? 477 ALA A O   1 
ATOM   2475  C CB  . ALA A 1 478 ? 89.034  85.948  147.614 1.00 248.41 ? 477 ALA A CB  1 
ATOM   2476  N N   . ALA A 1 479 ? 86.493  85.628  145.484 1.00 181.98 ? 478 ALA A N   1 
ATOM   2477  C CA  . ALA A 1 479 ? 85.285  86.341  145.086 1.00 204.28 ? 478 ALA A CA  1 
ATOM   2478  C C   . ALA A 1 479 ? 84.017  85.485  145.229 1.00 241.75 ? 478 ALA A C   1 
ATOM   2479  O O   . ALA A 1 479 ? 82.944  86.054  145.446 1.00 294.54 ? 478 ALA A O   1 
ATOM   2480  C CB  . ALA A 1 479 ? 85.448  86.822  143.662 1.00 260.39 ? 478 ALA A CB  1 
ATOM   2481  N N   . LEU A 1 480 ? 84.154  84.148  145.101 1.00 195.59 ? 479 LEU A N   1 
ATOM   2482  C CA  . LEU A 1 480 ? 83.096  83.172  145.321 1.00 204.81 ? 479 LEU A CA  1 
ATOM   2483  C C   . LEU A 1 480 ? 83.501  82.285  146.497 1.00 197.41 ? 479 LEU A C   1 
ATOM   2484  O O   . LEU A 1 480 ? 84.115  81.253  146.272 1.00 260.47 ? 479 LEU A O   1 
ATOM   2485  C CB  . LEU A 1 480 ? 82.910  82.364  144.035 1.00 208.18 ? 479 LEU A CB  1 
ATOM   2486  C CG  . LEU A 1 480 ? 81.862  82.844  143.047 1.00 236.61 ? 479 LEU A CG  1 
ATOM   2487  C CD1 . LEU A 1 480 ? 81.970  84.319  142.725 1.00 263.43 ? 479 LEU A CD1 1 
ATOM   2488  C CD2 . LEU A 1 480 ? 81.998  81.977  141.811 1.00 232.94 ? 479 LEU A CD2 1 
ATOM   2489  N N   . PRO A 1 481 ? 83.195  82.669  147.758 1.00 227.82 ? 480 PRO A N   1 
ATOM   2490  C CA  . PRO A 1 481 ? 83.808  82.038  148.934 1.00 245.25 ? 480 PRO A CA  1 
ATOM   2491  C C   . PRO A 1 481 ? 83.629  80.524  149.096 1.00 224.01 ? 480 PRO A C   1 
ATOM   2492  O O   . PRO A 1 481 ? 82.630  79.949  148.662 1.00 173.33 ? 480 PRO A O   1 
ATOM   2493  C CB  . PRO A 1 481 ? 83.102  82.756  150.106 1.00 328.96 ? 480 PRO A CB  1 
ATOM   2494  C CG  . PRO A 1 481 ? 82.670  84.086  149.534 1.00 336.14 ? 480 PRO A CG  1 
ATOM   2495  C CD  . PRO A 1 481 ? 82.265  83.760  148.115 1.00 284.56 ? 480 PRO A CD  1 
ATOM   2496  N N   . GLY A 1 482 ? 84.630  79.902  149.742 1.00 253.33 ? 481 GLY A N   1 
ATOM   2497  C CA  . GLY A 1 482 ? 84.572  78.506  150.154 1.00 294.30 ? 481 GLY A CA  1 
ATOM   2498  C C   . GLY A 1 482 ? 85.466  77.590  149.318 1.00 292.70 ? 481 GLY A C   1 
ATOM   2499  O O   . GLY A 1 482 ? 86.047  76.641  149.855 1.00 292.49 ? 481 GLY A O   1 
ATOM   2500  N N   . GLN A 1 483 ? 85.561  77.878  148.009 1.00 278.42 ? 482 GLN A N   1 
ATOM   2501  C CA  . GLN A 1 483 ? 86.339  77.086  147.063 1.00 266.34 ? 482 GLN A CA  1 
ATOM   2502  C C   . GLN A 1 483 ? 87.835  77.212  147.371 1.00 245.21 ? 482 GLN A C   1 
ATOM   2503  O O   . GLN A 1 483 ? 88.288  78.247  147.877 1.00 224.65 ? 482 GLN A O   1 
ATOM   2504  C CB  . GLN A 1 483 ? 86.026  77.506  145.620 1.00 223.21 ? 482 GLN A CB  1 
ATOM   2505  C CG  . GLN A 1 483 ? 86.519  78.907  145.278 1.00 269.20 ? 482 GLN A CG  1 
ATOM   2506  C CD  . GLN A 1 483 ? 86.199  79.364  143.879 1.00 280.72 ? 482 GLN A CD  1 
ATOM   2507  O OE1 . GLN A 1 483 ? 85.980  78.561  142.979 1.00 229.12 ? 482 GLN A OE1 1 
ATOM   2508  N NE2 . GLN A 1 483 ? 86.183  80.671  143.696 1.00 275.10 ? 482 GLN A NE2 1 
ATOM   2509  N N   . PRO A 1 484 ? 88.647  76.166  147.076 1.00 243.13 ? 483 PRO A N   1 
ATOM   2510  C CA  . PRO A 1 484 ? 90.058  76.178  147.457 1.00 277.59 ? 483 PRO A CA  1 
ATOM   2511  C C   . PRO A 1 484 ? 90.911  77.081  146.560 1.00 255.53 ? 483 PRO A C   1 
ATOM   2512  O O   . PRO A 1 484 ? 90.717  77.160  145.339 1.00 210.47 ? 483 PRO A O   1 
ATOM   2513  C CB  . PRO A 1 484 ? 90.454  74.695  147.334 1.00 292.02 ? 483 PRO A CB  1 
ATOM   2514  C CG  . PRO A 1 484 ? 89.566  74.173  146.233 1.00 290.48 ? 483 PRO A CG  1 
ATOM   2515  C CD  . PRO A 1 484 ? 88.260  74.927  146.378 1.00 240.00 ? 483 PRO A CD  1 
ATOM   2516  N N   . MET A 1 485 ? 91.890  77.739  147.186 1.00 240.71 ? 484 MET A N   1 
ATOM   2517  C CA  . MET A 1 485 ? 92.851  78.568  146.476 1.00 288.56 ? 484 MET A CA  1 
ATOM   2518  C C   . MET A 1 485 ? 93.787  77.755  145.571 1.00 296.16 ? 484 MET A C   1 
ATOM   2519  O O   . MET A 1 485 ? 94.491  78.356  144.759 1.00 357.26 ? 484 MET A O   1 
ATOM   2520  C CB  . MET A 1 485 ? 93.680  79.373  147.483 1.00 363.95 ? 484 MET A CB  1 
ATOM   2521  C CG  . MET A 1 485 ? 92.851  80.405  148.230 1.00 424.28 ? 484 MET A CG  1 
ATOM   2522  S SD  . MET A 1 485 ? 93.827  81.811  148.825 1.00 512.69 ? 484 MET A SD  1 
ATOM   2523  C CE  . MET A 1 485 ? 95.217  80.967  149.578 1.00 531.05 ? 484 MET A CE  1 
ATOM   2524  N N   . GLU A 1 486 ? 93.809  76.418  145.708 1.00 248.05 ? 485 GLU A N   1 
ATOM   2525  C CA  . GLU A 1 486 ? 94.473  75.510  144.783 1.00 265.73 ? 485 GLU A CA  1 
ATOM   2526  C C   . GLU A 1 486 ? 93.801  75.452  143.402 1.00 235.78 ? 485 GLU A C   1 
ATOM   2527  O O   . GLU A 1 486 ? 94.505  75.295  142.398 1.00 296.52 ? 485 GLU A O   1 
ATOM   2528  C CB  . GLU A 1 486 ? 94.503  74.111  145.414 1.00 370.04 ? 485 GLU A CB  1 
ATOM   2529  C CG  . GLU A 1 486 ? 95.199  73.045  144.573 1.00 489.11 ? 485 GLU A CG  1 
ATOM   2530  C CD  . GLU A 1 486 ? 95.383  71.686  145.232 1.00 571.71 ? 485 GLU A CD  1 
ATOM   2531  O OE1 . GLU A 1 486 ? 94.879  71.487  146.359 1.00 610.88 ? 485 GLU A OE1 1 
ATOM   2532  O OE2 . GLU A 1 486 ? 96.035  70.822  144.611 1.00 609.08 ? 485 GLU A OE2 1 
ATOM   2533  N N   . ALA A 1 487 ? 92.460  75.543  143.340 1.00 137.62 ? 486 ALA A N   1 
ATOM   2534  C CA  . ALA A 1 487 ? 91.698  75.048  142.195 1.00 143.42 ? 486 ALA A CA  1 
ATOM   2535  C C   . ALA A 1 487 ? 90.305  75.675  142.117 1.00 91.55  ? 486 ALA A C   1 
ATOM   2536  O O   . ALA A 1 487 ? 89.274  75.019  142.309 1.00 107.35 ? 486 ALA A O   1 
ATOM   2537  C CB  . ALA A 1 487 ? 91.603  73.531  142.277 1.00 232.52 ? 486 ALA A CB  1 
ATOM   2538  N N   . PRO A 1 488 ? 90.212  76.972  141.821 1.00 82.77  ? 487 PRO A N   1 
ATOM   2539  C CA  . PRO A 1 488 ? 88.928  77.658  141.747 1.00 115.19 ? 487 PRO A CA  1 
ATOM   2540  C C   . PRO A 1 488 ? 88.173  77.310  140.487 1.00 85.73  ? 487 PRO A C   1 
ATOM   2541  O O   . PRO A 1 488 ? 88.783  77.080  139.471 1.00 65.26  ? 487 PRO A O   1 
ATOM   2542  C CB  . PRO A 1 488 ? 89.287  79.158  141.716 1.00 148.24 ? 487 PRO A CB  1 
ATOM   2543  C CG  . PRO A 1 488 ? 90.624  79.096  141.018 1.00 120.90 ? 487 PRO A CG  1 
ATOM   2544  C CD  . PRO A 1 488 ? 91.329  77.870  141.563 1.00 114.97 ? 487 PRO A CD  1 
ATOM   2545  N N   . VAL A 1 489 ? 86.835  77.286  140.613 1.00 109.28 ? 488 VAL A N   1 
ATOM   2546  C CA  . VAL A 1 489 ? 85.947  76.809  139.570 1.00 113.90 ? 488 VAL A CA  1 
ATOM   2547  C C   . VAL A 1 489 ? 85.847  77.883  138.518 1.00 82.07  ? 488 VAL A C   1 
ATOM   2548  O O   . VAL A 1 489 ? 85.587  79.001  138.840 1.00 91.62  ? 488 VAL A O   1 
ATOM   2549  C CB  . VAL A 1 489 ? 84.549  76.457  140.086 1.00 154.81 ? 488 VAL A CB  1 
ATOM   2550  C CG1 . VAL A 1 489 ? 83.609  76.088  138.940 1.00 186.76 ? 488 VAL A CG1 1 
ATOM   2551  C CG2 . VAL A 1 489 ? 84.648  75.345  141.142 1.00 191.61 ? 488 VAL A CG2 1 
ATOM   2552  N N   . MET A 1 490 ? 86.052  77.486  137.274 1.00 86.74  ? 489 MET A N   1 
ATOM   2553  C CA  . MET A 1 490 ? 86.185  78.410  136.172 1.00 91.45  ? 489 MET A CA  1 
ATOM   2554  C C   . MET A 1 490 ? 84.765  78.806  135.787 1.00 98.24  ? 489 MET A C   1 
ATOM   2555  O O   . MET A 1 490 ? 83.862  77.964  135.726 1.00 100.87 ? 489 MET A O   1 
ATOM   2556  C CB  . MET A 1 490 ? 86.902  77.724  135.002 1.00 97.49  ? 489 MET A CB  1 
ATOM   2557  C CG  . MET A 1 490 ? 86.946  78.470  133.709 1.00 111.43 ? 489 MET A CG  1 
ATOM   2558  S SD  . MET A 1 490 ? 87.839  79.974  133.876 1.00 109.33 ? 489 MET A SD  1 
ATOM   2559  C CE  . MET A 1 490 ? 88.073  80.383  132.138 1.00 100.02 ? 489 MET A CE  1 
ATOM   2560  N N   . LEU A 1 491 ? 84.573  80.109  135.541 1.00 81.88  ? 490 LEU A N   1 
ATOM   2561  C CA  . LEU A 1 491 ? 83.260  80.689  135.322 1.00 101.44 ? 490 LEU A CA  1 
ATOM   2562  C C   . LEU A 1 491 ? 83.026  80.909  133.828 1.00 117.64 ? 490 LEU A C   1 
ATOM   2563  O O   . LEU A 1 491 ? 83.281  81.983  133.264 1.00 94.60  ? 490 LEU A O   1 
ATOM   2564  C CB  . LEU A 1 491 ? 83.141  82.007  136.097 1.00 99.36  ? 490 LEU A CB  1 
ATOM   2565  C CG  . LEU A 1 491 ? 83.470  81.951  137.580 1.00 113.94 ? 490 LEU A CG  1 
ATOM   2566  C CD1 . LEU A 1 491 ? 83.095  83.288  138.199 1.00 207.20 ? 490 LEU A CD1 1 
ATOM   2567  C CD2 . LEU A 1 491 ? 82.770  80.810  138.335 1.00 88.26  ? 490 LEU A CD2 1 
ATOM   2568  N N   . TRP A 1 492 ? 82.487  79.876  133.184 1.00 114.62 ? 491 TRP A N   1 
ATOM   2569  C CA  . TRP A 1 492 ? 82.170  79.958  131.771 1.00 134.56 ? 491 TRP A CA  1 
ATOM   2570  C C   . TRP A 1 492 ? 80.972  80.858  131.512 1.00 171.72 ? 491 TRP A C   1 
ATOM   2571  O O   . TRP A 1 492 ? 81.049  81.689  130.611 1.00 162.47 ? 491 TRP A O   1 
ATOM   2572  C CB  . TRP A 1 492 ? 81.890  78.551  131.286 1.00 140.25 ? 491 TRP A CB  1 
ATOM   2573  C CG  . TRP A 1 492 ? 83.100  77.700  131.456 1.00 122.09 ? 491 TRP A CG  1 
ATOM   2574  C CD1 . TRP A 1 492 ? 83.355  76.791  132.433 1.00 141.86 ? 491 TRP A CD1 1 
ATOM   2575  C CD2 . TRP A 1 492 ? 84.239  77.711  130.587 1.00 120.76 ? 491 TRP A CD2 1 
ATOM   2576  N NE1 . TRP A 1 492 ? 84.579  76.221  132.219 1.00 125.70 ? 491 TRP A NE1 1 
ATOM   2577  C CE2 . TRP A 1 492 ? 85.141  76.768  131.103 1.00 103.70 ? 491 TRP A CE2 1 
ATOM   2578  C CE3 . TRP A 1 492 ? 84.576  78.422  129.430 1.00 141.83 ? 491 TRP A CE3 1 
ATOM   2579  C CZ2 . TRP A 1 492 ? 86.367  76.524  130.490 1.00 133.45 ? 491 TRP A CZ2 1 
ATOM   2580  C CZ3 . TRP A 1 492 ? 85.788  78.189  128.833 1.00 95.27  ? 491 TRP A CZ3 1 
ATOM   2581  C CH2 . TRP A 1 492 ? 86.659  77.253  129.364 1.00 119.77 ? 491 TRP A CH2 1 
ATOM   2582  N N   . ASP A 1 493 ? 79.895  80.670  132.299 1.00 169.20 ? 492 ASP A N   1 
ATOM   2583  C CA  . ASP A 1 493 ? 78.662  81.442  132.201 1.00 190.08 ? 492 ASP A CA  1 
ATOM   2584  C C   . ASP A 1 493 ? 77.996  81.466  133.578 1.00 178.29 ? 492 ASP A C   1 
ATOM   2585  O O   . ASP A 1 493 ? 78.493  80.820  134.495 1.00 171.88 ? 492 ASP A O   1 
ATOM   2586  C CB  . ASP A 1 493 ? 77.743  80.864  131.123 1.00 236.24 ? 492 ASP A CB  1 
ATOM   2587  C CG  . ASP A 1 493 ? 77.195  79.482  131.457 1.00 282.36 ? 492 ASP A CG  1 
ATOM   2588  O OD1 . ASP A 1 493 ? 76.489  79.373  132.480 1.00 279.61 ? 492 ASP A OD1 1 
ATOM   2589  O OD2 . ASP A 1 493 ? 77.482  78.520  130.697 1.00 296.61 ? 492 ASP A OD2 1 
ATOM   2590  N N   . GLU A 1 494 ? 76.856  82.172  133.733 1.00 203.04 ? 493 GLU A N   1 
ATOM   2591  C CA  . GLU A 1 494 ? 76.284  82.466  135.054 1.00 227.77 ? 493 GLU A CA  1 
ATOM   2592  C C   . GLU A 1 494 ? 75.865  81.211  135.838 1.00 192.48 ? 493 GLU A C   1 
ATOM   2593  O O   . GLU A 1 494 ? 75.693  81.320  137.068 1.00 166.25 ? 493 GLU A O   1 
ATOM   2594  C CB  . GLU A 1 494 ? 75.103  83.437  134.919 1.00 241.98 ? 493 GLU A CB  1 
ATOM   2595  C CG  . GLU A 1 494 ? 75.534  84.843  134.559 1.00 253.46 ? 493 GLU A CG  1 
ATOM   2596  C CD  . GLU A 1 494 ? 74.423  85.868  134.407 1.00 344.02 ? 493 GLU A CD  1 
ATOM   2597  O OE1 . GLU A 1 494 ? 73.794  86.191  135.424 1.00 358.74 ? 493 GLU A OE1 1 
ATOM   2598  O OE2 . GLU A 1 494 ? 74.176  86.340  133.265 1.00 438.38 ? 493 GLU A OE2 1 
ATOM   2599  N N   . SER A 1 495 ? 75.725  80.057  135.149 1.00 191.40 ? 494 SER A N   1 
ATOM   2600  C CA  . SER A 1 495 ? 75.451  78.781  135.800 1.00 214.48 ? 494 SER A CA  1 
ATOM   2601  C C   . SER A 1 495 ? 76.626  78.201  136.596 1.00 210.89 ? 494 SER A C   1 
ATOM   2602  O O   . SER A 1 495 ? 76.390  77.356  137.467 1.00 201.88 ? 494 SER A O   1 
ATOM   2603  C CB  . SER A 1 495 ? 75.016  77.761  134.780 1.00 216.40 ? 494 SER A CB  1 
ATOM   2604  O OG  . SER A 1 495 ? 76.111  77.328  133.977 1.00 198.11 ? 494 SER A OG  1 
ATOM   2605  N N   . SER A 1 496 ? 77.866  78.633  136.306 1.00 210.24 ? 495 SER A N   1 
ATOM   2606  C CA  . SER A 1 496 ? 79.053  77.809  136.472 1.00 203.52 ? 495 SER A CA  1 
ATOM   2607  C C   . SER A 1 496 ? 79.380  77.519  137.934 1.00 189.85 ? 495 SER A C   1 
ATOM   2608  O O   . SER A 1 496 ? 80.085  76.533  138.182 1.00 261.42 ? 495 SER A O   1 
ATOM   2609  C CB  . SER A 1 496 ? 80.245  78.438  135.779 1.00 180.75 ? 495 SER A CB  1 
ATOM   2610  O OG  . SER A 1 496 ? 79.988  78.678  134.393 1.00 108.22 ? 495 SER A OG  1 
ATOM   2611  N N   . PHE A 1 497 ? 78.903  78.353  138.880 1.00 152.30 ? 496 PHE A N   1 
ATOM   2612  C CA  . PHE A 1 497 ? 79.068  78.093  140.309 1.00 173.97 ? 496 PHE A CA  1 
ATOM   2613  C C   . PHE A 1 497 ? 77.688  78.054  140.944 1.00 183.11 ? 496 PHE A C   1 
ATOM   2614  O O   . PHE A 1 497 ? 77.240  79.042  141.533 1.00 239.38 ? 496 PHE A O   1 
ATOM   2615  C CB  . PHE A 1 497 ? 79.979  79.149  140.948 1.00 181.36 ? 496 PHE A CB  1 
ATOM   2616  C CG  . PHE A 1 497 ? 80.357  78.942  142.393 1.00 157.28 ? 496 PHE A CG  1 
ATOM   2617  C CD1 . PHE A 1 497 ? 81.276  77.964  142.765 1.00 209.18 ? 496 PHE A CD1 1 
ATOM   2618  C CD2 . PHE A 1 497 ? 79.807  79.735  143.390 1.00 175.64 ? 496 PHE A CD2 1 
ATOM   2619  C CE1 . PHE A 1 497 ? 81.631  77.781  144.098 1.00 229.77 ? 496 PHE A CE1 1 
ATOM   2620  C CE2 . PHE A 1 497 ? 80.162  79.555  144.724 1.00 222.43 ? 496 PHE A CE2 1 
ATOM   2621  C CZ  . PHE A 1 497 ? 81.072  78.576  145.074 1.00 231.53 ? 496 PHE A CZ  1 
ATOM   2622  N N   . PRO A 1 498 ? 76.984  76.909  140.833 1.00 233.50 ? 497 PRO A N   1 
ATOM   2623  C CA  . PRO A 1 498 ? 75.594  76.811  141.273 1.00 305.00 ? 497 PRO A CA  1 
ATOM   2624  C C   . PRO A 1 498 ? 75.417  76.650  142.784 1.00 278.39 ? 497 PRO A C   1 
ATOM   2625  O O   . PRO A 1 498 ? 74.284  76.743  143.251 1.00 272.82 ? 497 PRO A O   1 
ATOM   2626  C CB  . PRO A 1 498 ? 75.110  75.564  140.508 1.00 332.08 ? 497 PRO A CB  1 
ATOM   2627  C CG  . PRO A 1 498 ? 76.327  74.681  140.459 1.00 297.75 ? 497 PRO A CG  1 
ATOM   2628  C CD  . PRO A 1 498 ? 77.479  75.643  140.272 1.00 249.77 ? 497 PRO A CD  1 
ATOM   2629  N N   . ASP A 1 499 ? 76.518  76.431  143.527 1.00 243.50 ? 498 ASP A N   1 
ATOM   2630  C CA  . ASP A 1 499 ? 76.498  76.146  144.959 1.00 269.41 ? 498 ASP A CA  1 
ATOM   2631  C C   . ASP A 1 499 ? 76.013  77.344  145.793 1.00 243.86 ? 498 ASP A C   1 
ATOM   2632  O O   . ASP A 1 499 ? 75.556  77.149  146.923 1.00 290.81 ? 498 ASP A O   1 
ATOM   2633  C CB  . ASP A 1 499 ? 77.886  75.699  145.453 1.00 308.86 ? 498 ASP A CB  1 
ATOM   2634  C CG  . ASP A 1 499 ? 78.517  74.512  144.733 1.00 347.49 ? 498 ASP A CG  1 
ATOM   2635  O OD1 . ASP A 1 499 ? 77.847  73.918  143.868 1.00 369.26 ? 498 ASP A OD1 1 
ATOM   2636  O OD2 . ASP A 1 499 ? 79.685  74.187  145.050 1.00 355.56 ? 498 ASP A OD2 1 
ATOM   2637  N N   . ILE A 1 500 ? 76.137  78.576  145.261 1.00 215.83 ? 499 ILE A N   1 
ATOM   2638  C CA  . ILE A 1 500 ? 75.537  79.786  145.815 1.00 236.52 ? 499 ILE A CA  1 
ATOM   2639  C C   . ILE A 1 500 ? 74.984  80.565  144.622 1.00 253.10 ? 499 ILE A C   1 
ATOM   2640  O O   . ILE A 1 500 ? 75.645  81.481  144.123 1.00 246.02 ? 499 ILE A O   1 
ATOM   2641  C CB  . ILE A 1 500 ? 76.533  80.615  146.666 1.00 257.70 ? 499 ILE A CB  1 
ATOM   2642  C CG1 . ILE A 1 500 ? 77.262  79.760  147.717 1.00 310.58 ? 499 ILE A CG1 1 
ATOM   2643  C CG2 . ILE A 1 500 ? 75.821  81.818  147.292 1.00 244.90 ? 499 ILE A CG2 1 
ATOM   2644  C CD1 . ILE A 1 500 ? 78.326  80.492  148.526 1.00 331.80 ? 499 ILE A CD1 1 
ATOM   2645  N N   . PRO A 1 501 ? 73.771  80.222  144.121 1.00 296.37 ? 500 PRO A N   1 
ATOM   2646  C CA  . PRO A 1 501 ? 73.297  80.759  142.844 1.00 313.69 ? 500 PRO A CA  1 
ATOM   2647  C C   . PRO A 1 501 ? 72.947  82.246  142.982 1.00 295.97 ? 500 PRO A C   1 
ATOM   2648  O O   . PRO A 1 501 ? 72.451  82.685  144.025 1.00 248.63 ? 500 PRO A O   1 
ATOM   2649  C CB  . PRO A 1 501 ? 72.089  79.871  142.503 1.00 306.93 ? 500 PRO A CB  1 
ATOM   2650  C CG  . PRO A 1 501 ? 71.582  79.378  143.842 1.00 283.49 ? 500 PRO A CG  1 
ATOM   2651  C CD  . PRO A 1 501 ? 72.793  79.320  144.752 1.00 290.92 ? 500 PRO A CD  1 
ATOM   2652  N N   . GLY A 1 502 ? 73.232  83.013  141.917 1.00 267.66 ? 501 GLY A N   1 
ATOM   2653  C CA  . GLY A 1 502 ? 73.090  84.462  141.928 1.00 279.63 ? 501 GLY A CA  1 
ATOM   2654  C C   . GLY A 1 502 ? 74.341  85.231  142.371 1.00 306.51 ? 501 GLY A C   1 
ATOM   2655  O O   . GLY A 1 502 ? 74.359  86.453  142.217 1.00 237.33 ? 501 GLY A O   1 
ATOM   2656  N N   . ALA A 1 503 ? 75.376  84.549  142.908 1.00 318.93 ? 502 ALA A N   1 
ATOM   2657  C CA  . ALA A 1 503 ? 76.637  85.180  143.319 1.00 260.00 ? 502 ALA A CA  1 
ATOM   2658  C C   . ALA A 1 503 ? 77.521  85.561  142.119 1.00 205.82 ? 502 ALA A C   1 
ATOM   2659  O O   . ALA A 1 503 ? 78.237  86.558  142.163 1.00 198.31 ? 502 ALA A O   1 
ATOM   2660  C CB  . ALA A 1 503 ? 77.377  84.266  144.275 1.00 212.71 ? 502 ALA A CB  1 
ATOM   2661  N N   . VAL A 1 504 ? 77.467  84.773  141.036 1.00 195.90 ? 503 VAL A N   1 
ATOM   2662  C CA  . VAL A 1 504 ? 78.176  85.049  139.790 1.00 150.78 ? 503 VAL A CA  1 
ATOM   2663  C C   . VAL A 1 504 ? 77.476  86.184  139.043 1.00 181.51 ? 503 VAL A C   1 
ATOM   2664  O O   . VAL A 1 504 ? 76.333  86.048  138.629 1.00 222.71 ? 503 VAL A O   1 
ATOM   2665  C CB  . VAL A 1 504 ? 78.181  83.827  138.865 1.00 180.81 ? 503 VAL A CB  1 
ATOM   2666  C CG1 . VAL A 1 504 ? 78.851  84.141  137.536 1.00 207.23 ? 503 VAL A CG1 1 
ATOM   2667  C CG2 . VAL A 1 504 ? 78.787  82.620  139.523 1.00 150.68 ? 503 VAL A CG2 1 
ATOM   2668  N N   . SER A 1 505 ? 78.167  87.299  138.859 1.00 182.07 ? 504 SER A N   1 
ATOM   2669  C CA  . SER A 1 505 ? 77.774  88.361  137.953 1.00 170.15 ? 504 SER A CA  1 
ATOM   2670  C C   . SER A 1 505 ? 78.205  88.021  136.523 1.00 123.67 ? 504 SER A C   1 
ATOM   2671  O O   . SER A 1 505 ? 79.191  87.345  136.317 1.00 184.03 ? 504 SER A O   1 
ATOM   2672  C CB  . SER A 1 505 ? 78.397  89.651  138.472 1.00 200.16 ? 504 SER A CB  1 
ATOM   2673  O OG  . SER A 1 505 ? 78.106  90.777  137.633 1.00 203.41 ? 504 SER A OG  1 
ATOM   2674  N N   . ALA A 1 506 ? 77.499  88.540  135.529 1.00 153.85 ? 505 ALA A N   1 
ATOM   2675  C CA  . ALA A 1 506 ? 77.787  88.292  134.114 1.00 163.73 ? 505 ALA A CA  1 
ATOM   2676  C C   . ALA A 1 506 ? 79.219  88.635  133.738 1.00 144.53 ? 505 ALA A C   1 
ATOM   2677  O O   . ALA A 1 506 ? 79.902  87.771  133.198 1.00 219.20 ? 505 ALA A O   1 
ATOM   2678  C CB  . ALA A 1 506 ? 76.826  89.065  133.233 1.00 256.12 ? 505 ALA A CB  1 
ATOM   2679  N N   . ASN A 1 507 ? 79.652  89.863  134.044 1.00 144.97 ? 506 ASN A N   1 
ATOM   2680  C CA  . ASN A 1 507 ? 81.009  90.368  133.827 1.00 167.94 ? 506 ASN A CA  1 
ATOM   2681  C C   . ASN A 1 507 ? 82.140  89.510  134.443 1.00 134.45 ? 506 ASN A C   1 
ATOM   2682  O O   . ASN A 1 507 ? 83.274  89.613  133.969 1.00 201.10 ? 506 ASN A O   1 
ATOM   2683  C CB  . ASN A 1 507 ? 81.130  91.823  134.302 1.00 191.33 ? 506 ASN A CB  1 
ATOM   2684  C CG  . ASN A 1 507 ? 80.850  91.986  135.782 1.00 193.30 ? 506 ASN A CG  1 
ATOM   2685  O OD1 . ASN A 1 507 ? 80.522  91.003  136.444 1.00 128.27 ? 506 ASN A OD1 1 
ATOM   2686  N ND2 . ASN A 1 507 ? 80.972  93.202  136.308 1.00 235.20 ? 506 ASN A ND2 1 
ATOM   2687  N N   . MET A 1 508 ? 81.880  88.648  135.439 1.00 114.80 ? 507 MET A N   1 
ATOM   2688  C CA  . MET A 1 508 ? 82.864  87.685  135.944 1.00 131.53 ? 507 MET A CA  1 
ATOM   2689  C C   . MET A 1 508 ? 83.094  86.444  135.068 1.00 116.16 ? 507 MET A C   1 
ATOM   2690  O O   . MET A 1 508 ? 83.938  85.656  135.446 1.00 200.82 ? 507 MET A O   1 
ATOM   2691  C CB  . MET A 1 508 ? 82.429  87.136  137.319 1.00 125.15 ? 507 MET A CB  1 
ATOM   2692  C CG  . MET A 1 508 ? 82.220  88.201  138.371 1.00 153.64 ? 507 MET A CG  1 
ATOM   2693  S SD  . MET A 1 508 ? 81.632  87.399  139.867 1.00 193.01 ? 507 MET A SD  1 
ATOM   2694  C CE  . MET A 1 508 ? 83.192  86.754  140.460 1.00 236.52 ? 507 MET A CE  1 
ATOM   2695  N N   . THR A 1 509 ? 82.405  86.249  133.943 1.00 109.24 ? 508 THR A N   1 
ATOM   2696  C CA  . THR A 1 509 ? 82.346  84.962  133.255 1.00 119.00 ? 508 THR A CA  1 
ATOM   2697  C C   . THR A 1 509 ? 82.840  85.074  131.816 1.00 121.71 ? 508 THR A C   1 
ATOM   2698  O O   . THR A 1 509 ? 82.782  86.142  131.213 1.00 121.47 ? 508 THR A O   1 
ATOM   2699  C CB  . THR A 1 509 ? 80.921  84.411  133.165 1.00 132.40 ? 508 THR A CB  1 
ATOM   2700  O OG1 . THR A 1 509 ? 80.139  85.189  132.242 1.00 150.78 ? 508 THR A OG1 1 
ATOM   2701  C CG2 . THR A 1 509 ? 80.273  84.362  134.527 1.00 135.98 ? 508 THR A CG2 1 
ATOM   2702  N N   . VAL A 1 510 ? 83.300  83.950  131.246 1.00 94.04  ? 509 VAL A N   1 
ATOM   2703  C CA  . VAL A 1 510 ? 83.862  83.955  129.905 1.00 107.32 ? 509 VAL A CA  1 
ATOM   2704  C C   . VAL A 1 510 ? 82.842  84.477  128.899 1.00 146.85 ? 509 VAL A C   1 
ATOM   2705  O O   . VAL A 1 510 ? 83.183  85.309  128.048 1.00 133.73 ? 509 VAL A O   1 
ATOM   2706  C CB  . VAL A 1 510 ? 84.356  82.577  129.462 1.00 118.87 ? 509 VAL A CB  1 
ATOM   2707  C CG1 . VAL A 1 510 ? 84.814  82.637  128.007 1.00 107.77 ? 509 VAL A CG1 1 
ATOM   2708  C CG2 . VAL A 1 510 ? 85.464  82.032  130.354 1.00 138.24 ? 509 VAL A CG2 1 
ATOM   2709  N N   . LYS A 1 511 ? 81.611  83.971  129.021 1.00 171.28 ? 510 LYS A N   1 
ATOM   2710  C CA  . LYS A 1 511 ? 80.511  84.340  128.146 1.00 193.52 ? 510 LYS A CA  1 
ATOM   2711  C C   . LYS A 1 511 ? 80.276  85.839  128.239 1.00 161.22 ? 510 LYS A C   1 
ATOM   2712  O O   . LYS A 1 511 ? 80.041  86.485  127.193 1.00 136.52 ? 510 LYS A O   1 
ATOM   2713  C CB  . LYS A 1 511 ? 79.259  83.541  128.529 1.00 228.13 ? 510 LYS A CB  1 
ATOM   2714  C CG  . LYS A 1 511 ? 78.107  83.649  127.545 1.00 292.84 ? 510 LYS A CG  1 
ATOM   2715  C CD  . LYS A 1 511 ? 76.919  82.801  127.917 1.00 319.90 ? 510 LYS A CD  1 
ATOM   2716  C CE  . LYS A 1 511 ? 75.830  82.802  126.863 1.00 364.26 ? 510 LYS A CE  1 
ATOM   2717  N NZ  . LYS A 1 511 ? 76.233  82.115  125.610 1.00 392.55 ? 510 LYS A NZ  1 
ATOM   2718  N N   . GLY A 1 512 ? 80.335  86.361  129.489 1.00 136.32 ? 511 GLY A N   1 
ATOM   2719  C CA  . GLY A 1 512 ? 80.032  87.756  129.774 1.00 185.47 ? 511 GLY A CA  1 
ATOM   2720  C C   . GLY A 1 512 ? 81.122  88.735  129.365 1.00 149.88 ? 511 GLY A C   1 
ATOM   2721  O O   . GLY A 1 512 ? 80.846  89.926  129.226 1.00 175.63 ? 511 GLY A O   1 
ATOM   2722  N N   . GLN A 1 513 ? 82.345  88.226  129.209 1.00 127.76 ? 512 GLN A N   1 
ATOM   2723  C CA  . GLN A 1 513 ? 83.466  89.036  128.757 1.00 141.55 ? 512 GLN A CA  1 
ATOM   2724  C C   . GLN A 1 513 ? 83.590  88.936  127.256 1.00 113.35 ? 512 GLN A C   1 
ATOM   2725  O O   . GLN A 1 513 ? 83.989  89.933  126.653 1.00 189.97 ? 512 GLN A O   1 
ATOM   2726  C CB  . GLN A 1 513 ? 84.770  88.651  129.475 1.00 116.73 ? 512 GLN A CB  1 
ATOM   2727  C CG  . GLN A 1 513 ? 84.680  89.001  130.945 1.00 151.10 ? 512 GLN A CG  1 
ATOM   2728  C CD  . GLN A 1 513 ? 85.955  88.920  131.707 1.00 143.33 ? 512 GLN A CD  1 
ATOM   2729  O OE1 . GLN A 1 513 ? 87.027  88.926  131.135 1.00 159.18 ? 512 GLN A OE1 1 
ATOM   2730  N NE2 . GLN A 1 513 ? 85.812  88.878  133.015 1.00 172.29 ? 512 GLN A NE2 1 
ATOM   2731  N N   . SER A 1 514 ? 83.292  87.771  126.667 1.00 113.25 ? 513 SER A N   1 
ATOM   2732  C CA  . SER A 1 514 ? 83.627  87.520  125.275 1.00 181.87 ? 513 SER A CA  1 
ATOM   2733  C C   . SER A 1 514 ? 83.024  88.572  124.341 1.00 209.95 ? 513 SER A C   1 
ATOM   2734  O O   . SER A 1 514 ? 83.596  88.805  123.251 1.00 182.52 ? 513 SER A O   1 
ATOM   2735  C CB  . SER A 1 514 ? 83.209  86.119  124.872 1.00 208.10 ? 513 SER A CB  1 
ATOM   2736  O OG  . SER A 1 514 ? 83.966  85.119  125.560 1.00 166.27 ? 513 SER A OG  1 
ATOM   2737  N N   . GLU A 1 515 ? 81.887  89.158  124.793 1.00 183.12 ? 514 GLU A N   1 
ATOM   2738  C CA  . GLU A 1 515 ? 81.086  90.101  124.025 1.00 209.73 ? 514 GLU A CA  1 
ATOM   2739  C C   . GLU A 1 515 ? 81.629  91.528  124.072 1.00 205.59 ? 514 GLU A C   1 
ATOM   2740  O O   . GLU A 1 515 ? 81.337  92.302  123.157 1.00 247.75 ? 514 GLU A O   1 
ATOM   2741  C CB  . GLU A 1 515 ? 79.638  90.044  124.526 1.00 262.64 ? 514 GLU A CB  1 
ATOM   2742  C CG  . GLU A 1 515 ? 79.388  90.561  125.939 1.00 266.81 ? 514 GLU A CG  1 
ATOM   2743  C CD  . GLU A 1 515 ? 77.924  90.596  126.357 1.00 399.41 ? 514 GLU A CD  1 
ATOM   2744  O OE1 . GLU A 1 515 ? 77.243  89.562  126.193 1.00 459.18 ? 514 GLU A OE1 1 
ATOM   2745  O OE2 . GLU A 1 515 ? 77.466  91.653  126.852 1.00 444.77 ? 514 GLU A OE2 1 
ATOM   2746  N N   . ASP A 1 516 ? 82.416  91.876  125.108 1.00 188.12 ? 515 ASP A N   1 
ATOM   2747  C CA  . ASP A 1 516 ? 82.673  93.251  125.522 1.00 164.36 ? 515 ASP A CA  1 
ATOM   2748  C C   . ASP A 1 516 ? 84.111  93.657  125.160 1.00 124.50 ? 515 ASP A C   1 
ATOM   2749  O O   . ASP A 1 516 ? 85.048  93.108  125.754 1.00 310.98 ? 515 ASP A O   1 
ATOM   2750  C CB  . ASP A 1 516 ? 82.387  93.354  127.022 1.00 136.25 ? 515 ASP A CB  1 
ATOM   2751  C CG  . ASP A 1 516 ? 82.768  94.695  127.656 1.00 191.32 ? 515 ASP A CG  1 
ATOM   2752  O OD1 . ASP A 1 516 ? 83.290  95.605  126.913 1.00 131.19 ? 515 ASP A OD1 1 
ATOM   2753  O OD2 . ASP A 1 516 ? 82.546  94.826  128.902 1.00 213.34 ? 515 ASP A OD2 1 
ATOM   2754  N N   . PRO A 1 517 ? 84.356  94.581  124.199 1.00 115.68 ? 516 PRO A N   1 
ATOM   2755  C CA  . PRO A 1 517 ? 85.716  95.038  123.873 1.00 173.35 ? 516 PRO A CA  1 
ATOM   2756  C C   . PRO A 1 517 ? 86.544  95.630  125.013 1.00 161.50 ? 516 PRO A C   1 
ATOM   2757  O O   . PRO A 1 517 ? 87.774  95.546  124.951 1.00 158.64 ? 516 PRO A O   1 
ATOM   2758  C CB  . PRO A 1 517 ? 85.498  96.123  122.809 1.00 233.00 ? 516 PRO A CB  1 
ATOM   2759  C CG  . PRO A 1 517 ? 84.221  95.670  122.151 1.00 264.15 ? 516 PRO A CG  1 
ATOM   2760  C CD  . PRO A 1 517 ? 83.371  95.215  123.322 1.00 198.47 ? 516 PRO A CD  1 
ATOM   2761  N N   . GLY A 1 518 ? 85.861  96.195  126.024 1.00 162.41 ? 517 GLY A N   1 
ATOM   2762  C CA  . GLY A 1 518 ? 86.505  96.659  127.246 1.00 188.13 ? 517 GLY A CA  1 
ATOM   2763  C C   . GLY A 1 518 ? 86.982  95.566  128.216 1.00 127.83 ? 517 GLY A C   1 
ATOM   2764  O O   . GLY A 1 518 ? 87.783  95.865  129.080 1.00 210.33 ? 517 GLY A O   1 
ATOM   2765  N N   . SER A 1 519 ? 86.512  94.327  128.103 1.00 134.65 ? 518 SER A N   1 
ATOM   2766  C CA  . SER A 1 519 ? 86.734  93.298  129.119 1.00 134.04 ? 518 SER A CA  1 
ATOM   2767  C C   . SER A 1 519 ? 88.160  92.817  129.146 1.00 113.30 ? 518 SER A C   1 
ATOM   2768  O O   . SER A 1 519 ? 88.864  92.953  128.142 1.00 86.87  ? 518 SER A O   1 
ATOM   2769  C CB  . SER A 1 519 ? 85.904  92.055  128.863 1.00 166.33 ? 518 SER A CB  1 
ATOM   2770  O OG  . SER A 1 519 ? 86.318  91.431  127.644 1.00 103.90 ? 518 SER A OG  1 
ATOM   2771  N N   . LEU A 1 520 ? 88.507  92.218  130.298 1.00 118.85 ? 519 LEU A N   1 
ATOM   2772  C CA  . LEU A 1 520 ? 89.831  91.625  130.509 1.00 121.18 ? 519 LEU A CA  1 
ATOM   2773  C C   . LEU A 1 520 ? 90.186  90.592  129.435 1.00 85.17  ? 519 LEU A C   1 
ATOM   2774  O O   . LEU A 1 520 ? 91.211  90.668  128.804 1.00 76.31  ? 519 LEU A O   1 
ATOM   2775  C CB  . LEU A 1 520 ? 89.885  91.028  131.921 1.00 119.92 ? 519 LEU A CB  1 
ATOM   2776  C CG  . LEU A 1 520 ? 91.239  90.539  132.427 1.00 101.67 ? 519 LEU A CG  1 
ATOM   2777  C CD1 . LEU A 1 520 ? 92.406  91.435  132.059 1.00 135.87 ? 519 LEU A CD1 1 
ATOM   2778  C CD2 . LEU A 1 520 ? 91.206  90.452  133.929 1.00 117.86 ? 519 LEU A CD2 1 
ATOM   2779  N N   . LEU A 1 521 ? 89.310  89.647  129.177 1.00 98.09  ? 520 LEU A N   1 
ATOM   2780  C CA  . LEU A 1 521 ? 89.507  88.639  128.143 1.00 67.47  ? 520 LEU A CA  1 
ATOM   2781  C C   . LEU A 1 521 ? 89.560  89.229  126.732 1.00 67.12  ? 520 LEU A C   1 
ATOM   2782  O O   . LEU A 1 521 ? 90.259  88.666  125.905 1.00 79.38  ? 520 LEU A O   1 
ATOM   2783  C CB  . LEU A 1 521 ? 88.348  87.669  128.299 1.00 61.04  ? 520 LEU A CB  1 
ATOM   2784  C CG  . LEU A 1 521 ? 88.259  86.551  127.300 1.00 61.91  ? 520 LEU A CG  1 
ATOM   2785  C CD1 . LEU A 1 521 ? 89.350  85.630  127.530 1.00 81.30  ? 520 LEU A CD1 1 
ATOM   2786  C CD2 . LEU A 1 521 ? 86.998  85.765  127.509 1.00 101.43 ? 520 LEU A CD2 1 
ATOM   2787  N N   . SER A 1 522 ? 88.908  90.362  126.452 1.00 78.45  ? 521 SER A N   1 
ATOM   2788  C CA  . SER A 1 522 ? 89.138  91.032  125.184 1.00 121.27 ? 521 SER A CA  1 
ATOM   2789  C C   . SER A 1 522 ? 90.529  91.672  125.057 1.00 131.06 ? 521 SER A C   1 
ATOM   2790  O O   . SER A 1 522 ? 91.010  91.884  123.924 1.00 136.26 ? 521 SER A O   1 
ATOM   2791  C CB  . SER A 1 522 ? 88.050  92.035  124.945 1.00 193.56 ? 521 SER A CB  1 
ATOM   2792  O OG  . SER A 1 522 ? 86.826  91.346  124.727 1.00 185.75 ? 521 SER A OG  1 
ATOM   2793  N N   . LEU A 1 523 ? 91.161  91.984  126.201 1.00 104.79 ? 522 LEU A N   1 
ATOM   2794  C CA  . LEU A 1 523 ? 92.536  92.450  126.237 1.00 99.46  ? 522 LEU A CA  1 
ATOM   2795  C C   . LEU A 1 523 ? 93.455  91.258  126.064 1.00 76.10  ? 522 LEU A C   1 
ATOM   2796  O O   . LEU A 1 523 ? 94.469  91.355  125.381 1.00 100.39 ? 522 LEU A O   1 
ATOM   2797  C CB  . LEU A 1 523 ? 92.830  93.200  127.545 1.00 83.13  ? 522 LEU A CB  1 
ATOM   2798  C CG  . LEU A 1 523 ? 94.294  93.589  127.773 1.00 110.54 ? 522 LEU A CG  1 
ATOM   2799  C CD1 . LEU A 1 523 ? 94.788  94.634  126.682 1.00 102.47 ? 522 LEU A CD1 1 
ATOM   2800  C CD2 . LEU A 1 523 ? 94.520  94.005  129.245 1.00 137.95 ? 522 LEU A CD2 1 
ATOM   2801  N N   . PHE A 1 524 ? 93.165  90.145  126.725 1.00 76.31  ? 523 PHE A N   1 
ATOM   2802  C CA  . PHE A 1 524 ? 94.057  88.996  126.685 1.00 85.14  ? 523 PHE A CA  1 
ATOM   2803  C C   . PHE A 1 524 ? 94.101  88.521  125.267 1.00 79.98  ? 523 PHE A C   1 
ATOM   2804  O O   . PHE A 1 524 ? 95.186  88.268  124.772 1.00 94.79  ? 523 PHE A O   1 
ATOM   2805  C CB  . PHE A 1 524 ? 93.606  87.887  127.648 1.00 73.68  ? 523 PHE A CB  1 
ATOM   2806  C CG  . PHE A 1 524 ? 94.515  86.696  127.819 1.00 70.82  ? 523 PHE A CG  1 
ATOM   2807  C CD1 . PHE A 1 524 ? 94.780  85.840  126.784 1.00 66.50  ? 523 PHE A CD1 1 
ATOM   2808  C CD2 . PHE A 1 524 ? 95.143  86.433  129.030 1.00 88.52  ? 523 PHE A CD2 1 
ATOM   2809  C CE1 . PHE A 1 524 ? 95.591  84.741  126.982 1.00 79.83  ? 523 PHE A CE1 1 
ATOM   2810  C CE2 . PHE A 1 524 ? 95.995  85.333  129.215 1.00 99.51  ? 523 PHE A CE2 1 
ATOM   2811  C CZ  . PHE A 1 524 ? 96.188  84.464  128.189 1.00 73.58  ? 523 PHE A CZ  1 
ATOM   2812  N N   . ARG A 1 525 ? 92.927  88.360  124.666 1.00 87.40  ? 524 ARG A N   1 
ATOM   2813  C CA  . ARG A 1 525 ? 92.849  87.838  123.309 1.00 112.81 ? 524 ARG A CA  1 
ATOM   2814  C C   . ARG A 1 525 ? 93.619  88.758  122.391 1.00 93.01  ? 524 ARG A C   1 
ATOM   2815  O O   . ARG A 1 525 ? 94.327  88.244  121.537 1.00 111.43 ? 524 ARG A O   1 
ATOM   2816  C CB  . ARG A 1 525 ? 91.414  87.631  122.840 1.00 130.48 ? 524 ARG A CB  1 
ATOM   2817  C CG  . ARG A 1 525 ? 90.729  86.427  123.481 1.00 113.39 ? 524 ARG A CG  1 
ATOM   2818  C CD  . ARG A 1 525 ? 89.264  86.362  123.126 1.00 125.02 ? 524 ARG A CD  1 
ATOM   2819  N NE  . ARG A 1 525 ? 88.603  85.222  123.680 1.00 109.13 ? 524 ARG A NE  1 
ATOM   2820  C CZ  . ARG A 1 525 ? 87.304  85.035  123.649 1.00 139.88 ? 524 ARG A CZ  1 
ATOM   2821  N NH1 . ARG A 1 525 ? 86.781  83.913  124.131 1.00 153.18 ? 524 ARG A NH1 1 
ATOM   2822  N NH2 . ARG A 1 525 ? 86.542  86.004  123.163 1.00 201.93 ? 524 ARG A NH2 1 
ATOM   2823  N N   . ARG A 1 526 ? 93.512  90.060  122.616 1.00 64.55  ? 525 ARG A N   1 
ATOM   2824  C CA  . ARG A 1 526 ? 94.144  91.005  121.709 1.00 109.06 ? 525 ARG A CA  1 
ATOM   2825  C C   . ARG A 1 526 ? 95.677  90.966  121.784 1.00 85.73  ? 525 ARG A C   1 
ATOM   2826  O O   . ARG A 1 526 ? 96.354  90.970  120.764 1.00 78.65  ? 525 ARG A O   1 
ATOM   2827  C CB  . ARG A 1 526 ? 93.600  92.405  121.916 1.00 99.56  ? 525 ARG A CB  1 
ATOM   2828  C CG  . ARG A 1 526 ? 93.896  93.259  120.689 1.00 147.52 ? 525 ARG A CG  1 
ATOM   2829  C CD  . ARG A 1 526 ? 93.322  94.655  120.645 1.00 149.78 ? 525 ARG A CD  1 
ATOM   2830  N NE  . ARG A 1 526 ? 92.179  94.920  121.516 1.00 143.88 ? 525 ARG A NE  1 
ATOM   2831  C CZ  . ARG A 1 526 ? 91.936  96.120  122.018 1.00 183.86 ? 525 ARG A CZ  1 
ATOM   2832  N NH1 . ARG A 1 526 ? 91.179  96.271  123.088 1.00 193.47 ? 525 ARG A NH1 1 
ATOM   2833  N NH2 . ARG A 1 526 ? 92.501  97.165  121.444 1.00 233.69 ? 525 ARG A NH2 1 
ATOM   2834  N N   . LEU A 1 527 ? 96.179  90.889  122.994 1.00 88.32  ? 526 LEU A N   1 
ATOM   2835  C CA  . LEU A 1 527 ? 97.611  90.825  123.230 1.00 96.31  ? 526 LEU A CA  1 
ATOM   2836  C C   . LEU A 1 527 ? 98.205  89.507  122.781 1.00 86.29  ? 526 LEU A C   1 
ATOM   2837  O O   . LEU A 1 527 ? 99.319  89.501  122.271 1.00 85.89  ? 526 LEU A O   1 
ATOM   2838  C CB  . LEU A 1 527 ? 97.860  91.018  124.724 1.00 81.95  ? 526 LEU A CB  1 
ATOM   2839  C CG  . LEU A 1 527 ? 97.812  92.487  125.059 1.00 82.54  ? 526 LEU A CG  1 
ATOM   2840  C CD1 . LEU A 1 527 ? 97.763  92.609  126.559 1.00 75.32  ? 526 LEU A CD1 1 
ATOM   2841  C CD2 . LEU A 1 527 ? 99.016  93.214  124.379 1.00 93.61  ? 526 LEU A CD2 1 
ATOM   2842  N N   . SER A 1 528 ? 97.442  88.434  122.979 1.00 69.05  ? 527 SER A N   1 
ATOM   2843  C CA  . SER A 1 528 ? 97.924  87.126  122.630 1.00 93.13  ? 527 SER A CA  1 
ATOM   2844  C C   . SER A 1 528 ? 98.182  87.082  121.120 1.00 96.61  ? 527 SER A C   1 
ATOM   2845  O O   . SER A 1 528 ? 99.135  86.400  120.687 1.00 89.42  ? 527 SER A O   1 
ATOM   2846  C CB  . SER A 1 528 ? 96.979  86.052  123.161 1.00 83.28  ? 527 SER A CB  1 
ATOM   2847  O OG  . SER A 1 528 ? 97.610  84.758  123.038 1.00 98.04  ? 527 SER A OG  1 
ATOM   2848  N N   . ASP A 1 529 ? 97.352  87.839  120.365 1.00 84.42  ? 528 ASP A N   1 
ATOM   2849  C CA  . ASP A 1 529 ? 97.543  87.981  118.931 1.00 103.92 ? 528 ASP A CA  1 
ATOM   2850  C C   . ASP A 1 529 ? 98.908  88.586  118.657 1.00 91.43  ? 528 ASP A C   1 
ATOM   2851  O O   . ASP A 1 529 ? 99.710  88.011  117.938 1.00 126.40 ? 528 ASP A O   1 
ATOM   2852  C CB  . ASP A 1 529 ? 96.434  88.818  118.293 1.00 139.26 ? 528 ASP A CB  1 
ATOM   2853  C CG  . ASP A 1 529 ? 96.358  88.737  116.777 1.00 254.83 ? 528 ASP A CG  1 
ATOM   2854  O OD1 . ASP A 1 529 ? 96.529  87.629  116.208 1.00 337.83 ? 528 ASP A OD1 1 
ATOM   2855  O OD2 . ASP A 1 529 ? 96.126  89.797  116.172 1.00 336.96 ? 528 ASP A OD2 1 
ATOM   2856  N N   . GLN A 1 530 ? 99.155  89.742  119.232 1.00 69.21  ? 529 GLN A N   1 
ATOM   2857  C CA  . GLN A 1 530 ? 100.339 90.512  118.918 1.00 73.48  ? 529 GLN A CA  1 
ATOM   2858  C C   . GLN A 1 530 ? 101.596 89.712  119.229 1.00 87.80  ? 529 GLN A C   1 
ATOM   2859  O O   . GLN A 1 530 ? 102.478 89.674  118.398 1.00 123.16 ? 529 GLN A O   1 
ATOM   2860  C CB  . GLN A 1 530 ? 100.274 91.812  119.706 1.00 125.68 ? 529 GLN A CB  1 
ATOM   2861  C CG  . GLN A 1 530 ? 99.041  92.623  119.341 1.00 120.09 ? 529 GLN A CG  1 
ATOM   2862  C CD  . GLN A 1 530 ? 99.178  93.069  117.930 1.00 141.95 ? 529 GLN A CD  1 
ATOM   2863  O OE1 . GLN A 1 530 ? 100.302 93.099  117.420 1.00 123.78 ? 529 GLN A OE1 1 
ATOM   2864  N NE2 . GLN A 1 530 ? 98.045  93.423  117.339 1.00 207.64 ? 529 GLN A NE2 1 
ATOM   2865  N N   . ARG A 1 531 ? 101.656 89.075  120.408 1.00 84.88  ? 530 ARG A N   1 
ATOM   2866  C CA  . ARG A 1 531 ? 102.797 88.313  120.848 1.00 70.13  ? 530 ARG A CA  1 
ATOM   2867  C C   . ARG A 1 531 ? 103.034 87.122  119.989 1.00 91.77  ? 530 ARG A C   1 
ATOM   2868  O O   . ARG A 1 531 ? 104.153 86.587  120.076 1.00 140.58 ? 530 ARG A O   1 
ATOM   2869  C CB  . ARG A 1 531 ? 102.519 87.703  122.228 1.00 88.14  ? 530 ARG A CB  1 
ATOM   2870  C CG  . ARG A 1 531 ? 103.606 86.814  122.826 1.00 77.68  ? 530 ARG A CG  1 
ATOM   2871  C CD  . ARG A 1 531 ? 104.948 87.509  122.706 1.00 73.62  ? 530 ARG A CD  1 
ATOM   2872  N NE  . ARG A 1 531 ? 105.783 86.711  123.508 1.00 68.73  ? 530 ARG A NE  1 
ATOM   2873  C CZ  . ARG A 1 531 ? 106.344 85.613  123.052 1.00 81.28  ? 530 ARG A CZ  1 
ATOM   2874  N NH1 . ARG A 1 531 ? 107.181 84.886  123.767 1.00 116.55 ? 530 ARG A NH1 1 
ATOM   2875  N NH2 . ARG A 1 531 ? 106.083 85.242  121.834 1.00 77.19  ? 530 ARG A NH2 1 
ATOM   2876  N N   . SER A 1 532 ? 102.029 86.679  119.196 1.00 91.49  ? 531 SER A N   1 
ATOM   2877  C CA  . SER A 1 532 ? 102.232 85.438  118.457 1.00 106.79 ? 531 SER A CA  1 
ATOM   2878  C C   . SER A 1 532 ? 102.445 85.662  116.955 1.00 107.26 ? 531 SER A C   1 
ATOM   2879  O O   . SER A 1 532 ? 102.780 84.715  116.244 1.00 147.80 ? 531 SER A O   1 
ATOM   2880  C CB  . SER A 1 532 ? 101.114 84.522  118.803 1.00 115.00 ? 531 SER A CB  1 
ATOM   2881  O OG  . SER A 1 532 ? 99.880  85.058  118.346 1.00 116.19 ? 531 SER A OG  1 
ATOM   2882  N N   . LYS A 1 533 ? 102.262 86.902  116.483 1.00 91.34  ? 532 LYS A N   1 
ATOM   2883  C CA  . LYS A 1 533 ? 102.372 87.228  115.095 1.00 126.79 ? 532 LYS A CA  1 
ATOM   2884  C C   . LYS A 1 533 ? 103.586 88.117  114.810 1.00 103.82 ? 532 LYS A C   1 
ATOM   2885  O O   . LYS A 1 533 ? 104.163 87.946  113.742 1.00 143.04 ? 532 LYS A O   1 
ATOM   2886  C CB  . LYS A 1 533 ? 101.005 87.839  114.781 1.00 148.48 ? 532 LYS A CB  1 
ATOM   2887  C CG  . LYS A 1 533 ? 100.838 89.347  114.882 1.00 159.78 ? 532 LYS A CG  1 
ATOM   2888  C CD  . LYS A 1 533 ? 99.415  89.833  114.997 1.00 194.50 ? 532 LYS A CD  1 
ATOM   2889  C CE  . LYS A 1 533 ? 98.674  90.219  113.764 1.00 257.87 ? 532 LYS A CE  1 
ATOM   2890  N NZ  . LYS A 1 533 ? 97.427  90.939  114.038 1.00 305.08 ? 532 LYS A NZ  1 
ATOM   2891  N N   . GLU A 1 534 ? 103.918 89.047  115.713 1.00 80.14  ? 533 GLU A N   1 
ATOM   2892  C CA  . GLU A 1 534 ? 104.775 90.183  115.419 1.00 112.64 ? 533 GLU A CA  1 
ATOM   2893  C C   . GLU A 1 534 ? 106.229 89.805  115.661 1.00 84.36  ? 533 GLU A C   1 
ATOM   2894  O O   . GLU A 1 534 ? 106.611 89.402  116.739 1.00 99.10  ? 533 GLU A O   1 
ATOM   2895  C CB  . GLU A 1 534 ? 104.361 91.408  116.247 1.00 105.38 ? 533 GLU A CB  1 
ATOM   2896  C CG  . GLU A 1 534 ? 103.254 92.164  115.603 1.00 144.59 ? 533 GLU A CG  1 
ATOM   2897  C CD  . GLU A 1 534 ? 103.662 92.971  114.365 1.00 259.16 ? 533 GLU A CD  1 
ATOM   2898  O OE1 . GLU A 1 534 ? 104.877 92.949  113.953 1.00 228.88 ? 533 GLU A OE1 1 
ATOM   2899  O OE2 . GLU A 1 534 ? 102.766 93.641  113.798 1.00 325.93 ? 533 GLU A OE2 1 
ATOM   2900  N N   . ARG A 1 535 ? 107.068 89.971  114.665 1.00 95.96  ? 534 ARG A N   1 
ATOM   2901  C CA  . ARG A 1 535 ? 108.392 89.413  114.792 1.00 121.62 ? 534 ARG A CA  1 
ATOM   2902  C C   . ARG A 1 535 ? 109.135 90.125  115.913 1.00 95.84  ? 534 ARG A C   1 
ATOM   2903  O O   . ARG A 1 535 ? 109.990 89.554  116.547 1.00 96.87  ? 534 ARG A O   1 
ATOM   2904  C CB  . ARG A 1 535 ? 109.129 89.487  113.457 1.00 155.75 ? 534 ARG A CB  1 
ATOM   2905  C CG  . ARG A 1 535 ? 110.313 88.549  113.452 1.00 164.18 ? 534 ARG A CG  1 
ATOM   2906  C CD  . ARG A 1 535 ? 110.915 88.293  112.100 1.00 219.63 ? 534 ARG A CD  1 
ATOM   2907  N NE  . ARG A 1 535 ? 110.029 87.593  111.176 1.00 151.11 ? 534 ARG A NE  1 
ATOM   2908  C CZ  . ARG A 1 535 ? 109.648 88.075  109.994 1.00 191.15 ? 534 ARG A CZ  1 
ATOM   2909  N NH1 . ARG A 1 535 ? 108.935 87.297  109.198 1.00 250.12 ? 534 ARG A NH1 1 
ATOM   2910  N NH2 . ARG A 1 535 ? 109.969 89.299  109.569 1.00 211.34 ? 534 ARG A NH2 1 
ATOM   2911  N N   . SER A 1 536 ? 108.770 91.378  116.164 1.00 100.74 ? 535 SER A N   1 
ATOM   2912  C CA  . SER A 1 536 ? 109.427 92.191  117.179 1.00 94.35  ? 535 SER A CA  1 
ATOM   2913  C C   . SER A 1 536 ? 109.144 91.681  118.589 1.00 79.80  ? 535 SER A C   1 
ATOM   2914  O O   . SER A 1 536 ? 110.072 91.582  119.332 1.00 66.00  ? 535 SER A O   1 
ATOM   2915  C CB  . SER A 1 536 ? 108.964 93.586  117.019 1.00 104.33 ? 535 SER A CB  1 
ATOM   2916  O OG  . SER A 1 536 ? 109.972 94.471  117.345 1.00 65.08  ? 535 SER A OG  1 
ATOM   2917  N N   . LEU A 1 537 ? 107.895 91.339  118.940 1.00 84.72  ? 536 LEU A N   1 
ATOM   2918  C CA  . LEU A 1 537 ? 107.494 90.727  120.228 1.00 69.97  ? 536 LEU A CA  1 
ATOM   2919  C C   . LEU A 1 537 ? 107.927 89.274  120.279 1.00 77.57  ? 536 LEU A C   1 
ATOM   2920  O O   . LEU A 1 537 ? 108.280 88.809  121.368 1.00 105.07 ? 536 LEU A O   1 
ATOM   2921  C CB  . LEU A 1 537 ? 105.975 90.813  120.520 1.00 49.47  ? 536 LEU A CB  1 
ATOM   2922  C CG  . LEU A 1 537 ? 105.481 92.281  120.405 1.00 83.90  ? 536 LEU A CG  1 
ATOM   2923  C CD1 . LEU A 1 537 ? 104.036 92.473  120.860 1.00 69.39  ? 536 LEU A CD1 1 
ATOM   2924  C CD2 . LEU A 1 537 ? 106.371 93.332  121.159 1.00 92.98  ? 536 LEU A CD2 1 
ATOM   2925  N N   . LEU A 1 538 ? 107.923 88.580  119.129 1.00 85.05  ? 537 LEU A N   1 
ATOM   2926  C CA  . LEU A 1 538 ? 108.252 87.160  119.078 1.00 91.69  ? 537 LEU A CA  1 
ATOM   2927  C C   . LEU A 1 538 ? 109.680 86.919  119.472 1.00 93.02  ? 537 LEU A C   1 
ATOM   2928  O O   . LEU A 1 538 ? 109.849 85.913  120.152 1.00 172.87 ? 537 LEU A O   1 
ATOM   2929  C CB  . LEU A 1 538 ? 108.054 86.575  117.699 1.00 79.75  ? 537 LEU A CB  1 
ATOM   2930  C CG  . LEU A 1 538 ? 106.627 86.139  117.445 1.00 119.41 ? 537 LEU A CG  1 
ATOM   2931  C CD1 . LEU A 1 538 ? 106.306 86.124  115.953 1.00 158.21 ? 537 LEU A CD1 1 
ATOM   2932  C CD2 . LEU A 1 538 ? 106.438 84.775  118.052 1.00 133.41 ? 537 LEU A CD2 1 
ATOM   2933  N N   . HIS A 1 539 ? 110.628 87.783  119.053 1.00 66.87  ? 538 HIS A N   1 
ATOM   2934  C CA  . HIS A 1 539 ? 112.024 87.601  119.452 1.00 104.63 ? 538 HIS A CA  1 
ATOM   2935  C C   . HIS A 1 539 ? 112.957 88.796  119.294 1.00 96.33  ? 538 HIS A C   1 
ATOM   2936  O O   . HIS A 1 539 ? 114.197 88.630  119.326 1.00 89.03  ? 538 HIS A O   1 
ATOM   2937  C CB  . HIS A 1 539 ? 112.631 86.378  118.754 1.00 175.67 ? 538 HIS A CB  1 
ATOM   2938  C CG  . HIS A 1 539 ? 112.471 86.426  117.308 1.00 147.43 ? 538 HIS A CG  1 
ATOM   2939  N ND1 . HIS A 1 539 ? 112.914 87.474  116.548 1.00 106.45 ? 538 HIS A ND1 1 
ATOM   2940  C CD2 . HIS A 1 539 ? 111.905 85.536  116.522 1.00 146.41 ? 538 HIS A CD2 1 
ATOM   2941  C CE1 . HIS A 1 539 ? 112.597 87.199  115.323 1.00 108.40 ? 538 HIS A CE1 1 
ATOM   2942  N NE2 . HIS A 1 539 ? 112.000 86.032  115.282 1.00 149.63 ? 538 HIS A NE2 1 
ATOM   2943  N N   . GLY A 1 540 ? 112.353 89.988  119.233 1.00 83.33  ? 539 GLY A N   1 
ATOM   2944  C CA  . GLY A 1 540 ? 113.100 91.218  119.375 1.00 92.48  ? 539 GLY A CA  1 
ATOM   2945  C C   . GLY A 1 540 ? 113.969 91.354  120.633 1.00 94.43  ? 539 GLY A C   1 
ATOM   2946  O O   . GLY A 1 540 ? 113.881 90.608  121.606 1.00 110.46 ? 539 GLY A O   1 
ATOM   2947  N N   . ASP A 1 541 ? 114.831 92.372  120.554 1.00 97.55  ? 540 ASP A N   1 
ATOM   2948  C CA  . ASP A 1 541 ? 115.622 92.860  121.651 1.00 129.69 ? 540 ASP A CA  1 
ATOM   2949  C C   . ASP A 1 541 ? 114.689 93.592  122.599 1.00 117.98 ? 540 ASP A C   1 
ATOM   2950  O O   . ASP A 1 541 ? 113.493 93.636  122.337 1.00 88.90  ? 540 ASP A O   1 
ATOM   2951  C CB  . ASP A 1 541 ? 116.751 93.709  121.125 1.00 161.24 ? 540 ASP A CB  1 
ATOM   2952  C CG  . ASP A 1 541 ? 117.735 93.045  120.158 1.00 265.74 ? 540 ASP A CG  1 
ATOM   2953  O OD1 . ASP A 1 541 ? 117.915 91.797  120.228 1.00 244.65 ? 540 ASP A OD1 1 
ATOM   2954  O OD2 . ASP A 1 541 ? 118.318 93.796  119.325 1.00 322.44 ? 540 ASP A OD2 1 
ATOM   2955  N N   . PHE A 1 542 ? 115.251 94.060  123.729 1.00 89.45  ? 541 PHE A N   1 
ATOM   2956  C CA  . PHE A 1 542 ? 114.495 94.683  124.802 1.00 63.03  ? 541 PHE A CA  1 
ATOM   2957  C C   . PHE A 1 542 ? 115.386 95.767  125.393 1.00 95.80  ? 541 PHE A C   1 
ATOM   2958  O O   . PHE A 1 542 ? 116.501 95.455  125.811 1.00 131.04 ? 541 PHE A O   1 
ATOM   2959  C CB  . PHE A 1 542 ? 114.011 93.662  125.846 1.00 62.84  ? 541 PHE A CB  1 
ATOM   2960  C CG  . PHE A 1 542 ? 113.582 94.209  127.185 1.00 64.71  ? 541 PHE A CG  1 
ATOM   2961  C CD1 . PHE A 1 542 ? 114.500 94.434  128.143 1.00 70.29  ? 541 PHE A CD1 1 
ATOM   2962  C CD2 . PHE A 1 542 ? 112.272 94.515  127.515 1.00 77.54  ? 541 PHE A CD2 1 
ATOM   2963  C CE1 . PHE A 1 542 ? 114.104 94.950  129.356 1.00 79.61  ? 541 PHE A CE1 1 
ATOM   2964  C CE2 . PHE A 1 542 ? 111.899 95.041  128.732 1.00 57.94  ? 541 PHE A CE2 1 
ATOM   2965  C CZ  . PHE A 1 542 ? 112.805 95.260  129.641 1.00 66.34  ? 541 PHE A CZ  1 
ATOM   2966  N N   . HIS A 1 543 ? 114.882 97.018  125.440 1.00 88.53  ? 542 HIS A N   1 
ATOM   2967  C CA  . HIS A 1 543 ? 115.626 98.120  126.034 1.00 103.23 ? 542 HIS A CA  1 
ATOM   2968  C C   . HIS A 1 543 ? 114.662 98.829  126.944 1.00 109.85 ? 542 HIS A C   1 
ATOM   2969  O O   . HIS A 1 543 ? 113.764 99.474  126.429 1.00 162.49 ? 542 HIS A O   1 
ATOM   2970  C CB  . HIS A 1 543 ? 116.223 99.102  125.028 1.00 123.18 ? 542 HIS A CB  1 
ATOM   2971  C CG  . HIS A 1 543 ? 117.367 98.471  124.324 1.00 204.56 ? 542 HIS A CG  1 
ATOM   2972  N ND1 . HIS A 1 543 ? 117.379 97.962  123.032 1.00 302.27 ? 542 HIS A ND1 1 
ATOM   2973  C CD2 . HIS A 1 543 ? 118.583 98.272  124.825 1.00 222.86 ? 542 HIS A CD2 1 
ATOM   2974  C CE1 . HIS A 1 543 ? 118.585 97.474  122.769 1.00 310.12 ? 542 HIS A CE1 1 
ATOM   2975  N NE2 . HIS A 1 543 ? 119.337 97.650  123.847 1.00 276.28 ? 542 HIS A NE2 1 
ATOM   2976  N N   . ALA A 1 544 ? 114.860 98.708  128.263 1.00 84.46  ? 543 ALA A N   1 
ATOM   2977  C CA  . ALA A 1 544 ? 114.198 99.587  129.187 1.00 70.41  ? 543 ALA A CA  1 
ATOM   2978  C C   . ALA A 1 544 ? 114.780 101.005 129.159 1.00 93.82  ? 543 ALA A C   1 
ATOM   2979  O O   . ALA A 1 544 ? 115.977 101.168 128.936 1.00 141.42 ? 543 ALA A O   1 
ATOM   2980  C CB  . ALA A 1 544 ? 114.412 99.021  130.513 1.00 121.42 ? 543 ALA A CB  1 
ATOM   2981  N N   . PHE A 1 545 ? 113.945 102.022 129.422 1.00 73.62  ? 544 PHE A N   1 
ATOM   2982  C CA  . PHE A 1 545 ? 114.481 103.357 129.634 1.00 72.43  ? 544 PHE A CA  1 
ATOM   2983  C C   . PHE A 1 545 ? 113.653 104.205 130.594 1.00 115.55 ? 544 PHE A C   1 
ATOM   2984  O O   . PHE A 1 545 ? 112.514 103.832 130.911 1.00 91.48  ? 544 PHE A O   1 
ATOM   2985  C CB  . PHE A 1 545 ? 114.529 104.000 128.288 1.00 66.12  ? 544 PHE A CB  1 
ATOM   2986  C CG  . PHE A 1 545 ? 113.238 104.346 127.630 1.00 60.27  ? 544 PHE A CG  1 
ATOM   2987  C CD1 . PHE A 1 545 ? 112.587 103.450 126.808 1.00 49.78  ? 544 PHE A CD1 1 
ATOM   2988  C CD2 . PHE A 1 545 ? 112.739 105.633 127.774 1.00 89.97  ? 544 PHE A CD2 1 
ATOM   2989  C CE1 . PHE A 1 545 ? 111.407 103.794 126.201 1.00 62.90  ? 544 PHE A CE1 1 
ATOM   2990  C CE2 . PHE A 1 545 ? 111.559 105.986 127.122 1.00 94.39  ? 544 PHE A CE2 1 
ATOM   2991  C CZ  . PHE A 1 545 ? 110.891 105.060 126.339 1.00 86.51  ? 544 PHE A CZ  1 
ATOM   2992  N N   . SER A 1 546 ? 114.238 105.330 131.072 1.00 99.30  ? 545 SER A N   1 
ATOM   2993  C CA  . SER A 1 546 ? 113.556 106.134 132.086 1.00 97.50  ? 545 SER A CA  1 
ATOM   2994  C C   . SER A 1 546 ? 112.734 107.133 131.315 1.00 61.53  ? 545 SER A C   1 
ATOM   2995  O O   . SER A 1 546 ? 113.265 108.094 130.733 1.00 112.75 ? 545 SER A O   1 
ATOM   2996  C CB  . SER A 1 546 ? 114.468 106.809 133.079 1.00 160.49 ? 545 SER A CB  1 
ATOM   2997  O OG  . SER A 1 546 ? 115.496 105.938 133.561 1.00 215.25 ? 545 SER A OG  1 
ATOM   2998  N N   . ALA A 1 547 ? 111.440 106.897 131.259 1.00 64.16  ? 546 ALA A N   1 
ATOM   2999  C CA  . ALA A 1 547 ? 110.573 107.667 130.359 1.00 68.54  ? 546 ALA A CA  1 
ATOM   3000  C C   . ALA A 1 547 ? 109.799 108.659 131.148 1.00 76.34  ? 546 ALA A C   1 
ATOM   3001  O O   . ALA A 1 547 ? 109.167 109.385 130.448 1.00 58.70  ? 546 ALA A O   1 
ATOM   3002  C CB  . ALA A 1 547 ? 109.502 106.829 129.707 1.00 89.36  ? 546 ALA A CB  1 
ATOM   3003  N N   . GLY A 1 548 ? 109.825 108.643 132.513 1.00 79.47  ? 547 GLY A N   1 
ATOM   3004  C CA  . GLY A 1 548 ? 108.767 109.241 133.345 1.00 51.41  ? 547 GLY A CA  1 
ATOM   3005  C C   . GLY A 1 548 ? 108.858 108.716 134.751 1.00 56.21  ? 547 GLY A C   1 
ATOM   3006  O O   . GLY A 1 548 ? 109.580 107.725 134.891 1.00 78.71  ? 547 GLY A O   1 
ATOM   3007  N N   . PRO A 1 549 ? 108.306 109.378 135.822 1.00 56.91  ? 548 PRO A N   1 
ATOM   3008  C CA  . PRO A 1 549 ? 108.400 108.966 137.231 1.00 46.54  ? 548 PRO A CA  1 
ATOM   3009  C C   . PRO A 1 549 ? 107.909 107.572 137.507 1.00 70.21  ? 548 PRO A C   1 
ATOM   3010  O O   . PRO A 1 549 ? 108.809 106.775 137.794 1.00 105.18 ? 548 PRO A O   1 
ATOM   3011  C CB  . PRO A 1 549 ? 107.830 110.135 137.958 1.00 33.88  ? 548 PRO A CB  1 
ATOM   3012  C CG  . PRO A 1 549 ? 108.382 111.191 137.110 1.00 32.59  ? 548 PRO A CG  1 
ATOM   3013  C CD  . PRO A 1 549 ? 107.738 110.701 135.836 1.00 56.09  ? 548 PRO A CD  1 
ATOM   3014  N N   . GLY A 1 550 ? 106.641 107.220 137.372 1.00 67.62  ? 549 GLY A N   1 
ATOM   3015  C CA  . GLY A 1 550 ? 106.342 105.815 137.680 1.00 90.96  ? 549 GLY A CA  1 
ATOM   3016  C C   . GLY A 1 550 ? 106.782 104.759 136.651 1.00 62.15  ? 549 GLY A C   1 
ATOM   3017  O O   . GLY A 1 550 ? 107.068 103.586 136.926 1.00 74.89  ? 549 GLY A O   1 
ATOM   3018  N N   . LEU A 1 551 ? 106.806 105.226 135.428 1.00 65.08  ? 550 LEU A N   1 
ATOM   3019  C CA  . LEU A 1 551 ? 106.718 104.378 134.265 1.00 64.69  ? 550 LEU A CA  1 
ATOM   3020  C C   . LEU A 1 551 ? 107.880 103.392 134.257 1.00 79.88  ? 550 LEU A C   1 
ATOM   3021  O O   . LEU A 1 551 ? 109.067 103.752 134.431 1.00 70.91  ? 550 LEU A O   1 
ATOM   3022  C CB  . LEU A 1 551 ? 106.823 105.206 132.995 1.00 64.48  ? 550 LEU A CB  1 
ATOM   3023  C CG  . LEU A 1 551 ? 106.012 106.478 132.957 1.00 78.18  ? 550 LEU A CG  1 
ATOM   3024  C CD1 . LEU A 1 551 ? 106.296 107.222 131.636 1.00 113.17 ? 550 LEU A CD1 1 
ATOM   3025  C CD2 . LEU A 1 551 ? 104.565 106.095 133.181 1.00 57.26  ? 550 LEU A CD2 1 
ATOM   3026  N N   . PHE A 1 552 ? 107.484 102.126 134.062 1.00 65.57  ? 551 PHE A N   1 
ATOM   3027  C CA  . PHE A 1 552 ? 108.360 101.112 133.495 1.00 54.82  ? 551 PHE A CA  1 
ATOM   3028  C C   . PHE A 1 552 ? 108.154 101.195 132.030 1.00 56.99  ? 551 PHE A C   1 
ATOM   3029  O O   . PHE A 1 552 ? 107.041 100.984 131.610 1.00 43.99  ? 551 PHE A O   1 
ATOM   3030  C CB  . PHE A 1 552 ? 107.944 99.703  133.848 1.00 47.89  ? 551 PHE A CB  1 
ATOM   3031  C CG  . PHE A 1 552 ? 108.800 98.557  133.439 1.00 37.60  ? 551 PHE A CG  1 
ATOM   3032  C CD1 . PHE A 1 552 ? 110.071 98.680  133.033 1.00 47.82  ? 551 PHE A CD1 1 
ATOM   3033  C CD2 . PHE A 1 552 ? 108.276 97.287  133.545 1.00 48.32  ? 551 PHE A CD2 1 
ATOM   3034  C CE1 . PHE A 1 552 ? 110.796 97.558  132.668 1.00 67.23  ? 551 PHE A CE1 1 
ATOM   3035  C CE2 . PHE A 1 552 ? 109.012 96.163  133.214 1.00 54.40  ? 551 PHE A CE2 1 
ATOM   3036  C CZ  . PHE A 1 552 ? 110.272 96.311  132.763 1.00 58.25  ? 551 PHE A CZ  1 
ATOM   3037  N N   . SER A 1 553 ? 109.204 101.546 131.305 1.00 69.95  ? 552 SER A N   1 
ATOM   3038  C CA  . SER A 1 553 ? 108.971 101.755 129.907 1.00 75.97  ? 552 SER A CA  1 
ATOM   3039  C C   . SER A 1 553 ? 110.049 101.092 129.102 1.00 83.71  ? 552 SER A C   1 
ATOM   3040  O O   . SER A 1 553 ? 111.189 101.155 129.533 1.00 125.25 ? 552 SER A O   1 
ATOM   3041  C CB  . SER A 1 553 ? 108.843 103.179 129.621 1.00 66.20  ? 552 SER A CB  1 
ATOM   3042  O OG  . SER A 1 553 ? 108.550 103.230 128.262 1.00 96.91  ? 552 SER A OG  1 
ATOM   3043  N N   . TYR A 1 554 ? 109.669 100.457 127.979 1.00 51.90  ? 553 TYR A N   1 
ATOM   3044  C CA  . TYR A 1 554 ? 110.687 99.733  127.240 1.00 68.29  ? 553 TYR A CA  1 
ATOM   3045  C C   . TYR A 1 554 ? 110.267 99.510  125.820 1.00 68.66  ? 553 TYR A C   1 
ATOM   3046  O O   . TYR A 1 554 ? 109.106 99.479  125.569 1.00 48.85  ? 553 TYR A O   1 
ATOM   3047  C CB  . TYR A 1 554 ? 111.055 98.323  127.724 1.00 71.85  ? 553 TYR A CB  1 
ATOM   3048  C CG  . TYR A 1 554 ? 109.853 97.523  128.064 1.00 72.02  ? 553 TYR A CG  1 
ATOM   3049  C CD1 . TYR A 1 554 ? 109.361 96.682  127.074 1.00 43.73  ? 553 TYR A CD1 1 
ATOM   3050  C CD2 . TYR A 1 554 ? 109.255 97.627  129.325 1.00 71.54  ? 553 TYR A CD2 1 
ATOM   3051  C CE1 . TYR A 1 554 ? 108.288 95.892  127.327 1.00 42.51  ? 553 TYR A CE1 1 
ATOM   3052  C CE2 . TYR A 1 554 ? 108.152 96.853  129.570 1.00 66.62  ? 553 TYR A CE2 1 
ATOM   3053  C CZ  . TYR A 1 554 ? 107.704 95.979  128.575 1.00 55.09  ? 553 TYR A CZ  1 
ATOM   3054  O OH  . TYR A 1 554 ? 106.610 95.202  128.762 1.00 60.86  ? 553 TYR A OH  1 
ATOM   3055  N N   . ILE A 1 555 ? 111.262 99.343  124.936 1.00 97.85  ? 554 ILE A N   1 
ATOM   3056  C CA  . ILE A 1 555 ? 111.045 99.141  123.527 1.00 78.31  ? 554 ILE A CA  1 
ATOM   3057  C C   . ILE A 1 555 ? 111.444 97.730  123.183 1.00 65.61  ? 554 ILE A C   1 
ATOM   3058  O O   . ILE A 1 555 ? 112.530 97.314  123.550 1.00 90.33  ? 554 ILE A O   1 
ATOM   3059  C CB  . ILE A 1 555 ? 111.859 100.154 122.763 1.00 76.71  ? 554 ILE A CB  1 
ATOM   3060  C CG1 . ILE A 1 555 ? 111.306 101.552 123.018 1.00 91.10  ? 554 ILE A CG1 1 
ATOM   3061  C CG2 . ILE A 1 555 ? 111.755 99.789  121.318 1.00 100.96 ? 554 ILE A CG2 1 
ATOM   3062  C CD1 . ILE A 1 555 ? 112.246 102.626 122.571 1.00 147.49 ? 554 ILE A CD1 1 
ATOM   3063  N N   . ARG A 1 556 ? 110.555 97.036  122.475 1.00 56.61  ? 555 ARG A N   1 
ATOM   3064  C CA  . ARG A 1 556 ? 110.882 95.784  121.830 1.00 58.17  ? 555 ARG A CA  1 
ATOM   3065  C C   . ARG A 1 556 ? 111.166 96.094  120.373 1.00 81.24  ? 555 ARG A C   1 
ATOM   3066  O O   . ARG A 1 556 ? 110.378 96.783  119.746 1.00 74.93  ? 555 ARG A O   1 
ATOM   3067  C CB  . ARG A 1 556 ? 109.713 94.796  121.859 1.00 61.57  ? 555 ARG A CB  1 
ATOM   3068  C CG  . ARG A 1 556 ? 109.304 94.264  123.214 1.00 59.90  ? 555 ARG A CG  1 
ATOM   3069  C CD  . ARG A 1 556 ? 110.497 93.725  123.961 1.00 53.88  ? 555 ARG A CD  1 
ATOM   3070  N NE  . ARG A 1 556 ? 110.999 92.590  123.287 1.00 49.32  ? 555 ARG A NE  1 
ATOM   3071  C CZ  . ARG A 1 556 ? 110.458 91.364  123.302 1.00 62.54  ? 555 ARG A CZ  1 
ATOM   3072  N NH1 . ARG A 1 556 ? 111.136 90.363  122.758 1.00 79.39  ? 555 ARG A NH1 1 
ATOM   3073  N NH2 . ARG A 1 556 ? 109.266 91.082  123.822 1.00 63.47  ? 555 ARG A NH2 1 
ATOM   3074  N N   . HIS A 1 557 ? 112.278 95.582  119.823 1.00 100.50 ? 556 HIS A N   1 
ATOM   3075  C CA  . HIS A 1 557 ? 112.572 95.808  118.417 1.00 84.02  ? 556 HIS A CA  1 
ATOM   3076  C C   . HIS A 1 557 ? 113.326 94.654  117.806 1.00 99.27  ? 556 HIS A C   1 
ATOM   3077  O O   . HIS A 1 557 ? 114.024 93.986  118.537 1.00 131.51 ? 556 HIS A O   1 
ATOM   3078  C CB  . HIS A 1 557 ? 113.419 97.072  118.212 1.00 107.75 ? 556 HIS A CB  1 
ATOM   3079  C CG  . HIS A 1 557 ? 114.698 97.176  118.958 1.00 98.79  ? 556 HIS A CG  1 
ATOM   3080  N ND1 . HIS A 1 557 ? 115.811 96.451  118.657 1.00 142.96 ? 556 HIS A ND1 1 
ATOM   3081  C CD2 . HIS A 1 557 ? 115.032 97.942  119.988 1.00 136.93 ? 556 HIS A CD2 1 
ATOM   3082  C CE1 . HIS A 1 557 ? 116.771 96.796  119.509 1.00 184.69 ? 556 HIS A CE1 1 
ATOM   3083  N NE2 . HIS A 1 557 ? 116.307 97.692  120.319 1.00 176.42 ? 556 HIS A NE2 1 
ATOM   3084  N N   . TRP A 1 558 ? 113.204 94.497  116.476 1.00 126.51 ? 557 TRP A N   1 
ATOM   3085  C CA  . TRP A 1 558 ? 113.992 93.605  115.623 1.00 133.79 ? 557 TRP A CA  1 
ATOM   3086  C C   . TRP A 1 558 ? 114.407 94.303  114.338 1.00 155.47 ? 557 TRP A C   1 
ATOM   3087  O O   . TRP A 1 558 ? 113.847 95.361  114.043 1.00 211.16 ? 557 TRP A O   1 
ATOM   3088  C CB  . TRP A 1 558 ? 113.134 92.414  115.265 1.00 89.88  ? 557 TRP A CB  1 
ATOM   3089  C CG  . TRP A 1 558 ? 113.834 91.282  114.576 1.00 85.37  ? 557 TRP A CG  1 
ATOM   3090  C CD1 . TRP A 1 558 ? 113.389 90.727  113.436 1.00 108.36 ? 557 TRP A CD1 1 
ATOM   3091  C CD2 . TRP A 1 558 ? 114.998 90.519  114.963 1.00 99.67  ? 557 TRP A CD2 1 
ATOM   3092  N NE1 . TRP A 1 558 ? 114.201 89.702  113.075 1.00 128.91 ? 557 TRP A NE1 1 
ATOM   3093  C CE2 . TRP A 1 558 ? 115.185 89.536  113.995 1.00 90.20  ? 557 TRP A CE2 1 
ATOM   3094  C CE3 . TRP A 1 558 ? 115.901 90.548  116.026 1.00 187.72 ? 557 TRP A CE3 1 
ATOM   3095  C CZ2 . TRP A 1 558 ? 116.215 88.618  114.053 1.00 140.36 ? 557 TRP A CZ2 1 
ATOM   3096  C CZ3 . TRP A 1 558 ? 116.921 89.626  116.106 1.00 166.47 ? 557 TRP A CZ3 1 
ATOM   3097  C CH2 . TRP A 1 558 ? 117.063 88.665  115.132 1.00 164.04 ? 557 TRP A CH2 1 
ATOM   3098  N N   . ASP A 1 559 ? 115.341 93.706  113.601 1.00 137.82 ? 558 ASP A N   1 
ATOM   3099  C CA  . ASP A 1 559 ? 116.268 94.486  112.800 1.00 209.97 ? 558 ASP A CA  1 
ATOM   3100  C C   . ASP A 1 559 ? 115.591 95.637  112.048 1.00 169.57 ? 558 ASP A C   1 
ATOM   3101  O O   . ASP A 1 559 ? 116.081 96.777  112.194 1.00 277.90 ? 558 ASP A O   1 
ATOM   3102  C CB  . ASP A 1 559 ? 117.132 93.632  111.862 1.00 275.94 ? 558 ASP A CB  1 
ATOM   3103  C CG  . ASP A 1 559 ? 116.456 92.746  110.829 1.00 249.59 ? 558 ASP A CG  1 
ATOM   3104  O OD1 . ASP A 1 559 ? 115.219 92.889  110.606 1.00 171.71 ? 558 ASP A OD1 1 
ATOM   3105  O OD2 . ASP A 1 559 ? 117.197 91.921  110.240 1.00 262.64 ? 558 ASP A OD2 1 
ATOM   3106  N N   . GLN A 1 560 ? 114.538 95.378  111.235 1.00 110.60 ? 559 GLN A N   1 
ATOM   3107  C CA  . GLN A 1 560 ? 113.896 96.507  110.550 1.00 134.87 ? 559 GLN A CA  1 
ATOM   3108  C C   . GLN A 1 560 ? 112.385 96.457  110.634 1.00 130.33 ? 559 GLN A C   1 
ATOM   3109  O O   . GLN A 1 560 ? 111.725 97.368  110.101 1.00 146.95 ? 559 GLN A O   1 
ATOM   3110  C CB  . GLN A 1 560 ? 114.284 96.635  109.074 1.00 140.84 ? 559 GLN A CB  1 
ATOM   3111  C CG  . GLN A 1 560 ? 115.804 96.738  108.858 1.00 184.45 ? 559 GLN A CG  1 
ATOM   3112  C CD  . GLN A 1 560 ? 116.174 97.066  107.437 1.00 185.12 ? 559 GLN A CD  1 
ATOM   3113  O OE1 . GLN A 1 560 ? 115.362 97.621  106.690 1.00 123.67 ? 559 GLN A OE1 1 
ATOM   3114  N NE2 . GLN A 1 560 ? 117.401 96.719  107.067 1.00 203.02 ? 559 GLN A NE2 1 
ATOM   3115  N N   . ASN A 1 561 ? 111.849 95.433  111.315 1.00 109.11 ? 560 ASN A N   1 
ATOM   3116  C CA  . ASN A 1 561 ? 110.399 95.296  111.365 1.00 121.89 ? 560 ASN A CA  1 
ATOM   3117  C C   . ASN A 1 561 ? 109.832 96.408  112.270 1.00 139.38 ? 560 ASN A C   1 
ATOM   3118  O O   . ASN A 1 561 ? 110.569 97.243  112.783 1.00 155.13 ? 560 ASN A O   1 
ATOM   3119  C CB  . ASN A 1 561 ? 109.985 93.858  111.744 1.00 90.39  ? 560 ASN A CB  1 
ATOM   3120  C CG  . ASN A 1 561 ? 110.585 92.730  110.904 1.00 182.74 ? 560 ASN A CG  1 
ATOM   3121  O OD1 . ASN A 1 561 ? 110.542 91.595  111.320 1.00 162.38 ? 560 ASN A OD1 1 
ATOM   3122  N ND2 . ASN A 1 561 ? 111.126 92.936  109.712 1.00 244.94 ? 560 ASN A ND2 1 
ATOM   3123  N N   . GLU A 1 562 ? 108.514 96.414  112.488 1.00 147.93 ? 561 GLU A N   1 
ATOM   3124  C CA  . GLU A 1 562 ? 107.861 97.311  113.441 1.00 145.44 ? 561 GLU A CA  1 
ATOM   3125  C C   . GLU A 1 562 ? 108.461 97.275  114.861 1.00 126.49 ? 561 GLU A C   1 
ATOM   3126  O O   . GLU A 1 562 ? 108.824 96.219  115.373 1.00 132.98 ? 561 GLU A O   1 
ATOM   3127  C CB  . GLU A 1 562 ? 106.387 96.949  113.605 1.00 168.07 ? 561 GLU A CB  1 
ATOM   3128  C CG  . GLU A 1 562 ? 105.518 98.165  113.811 1.00 189.40 ? 561 GLU A CG  1 
ATOM   3129  C CD  . GLU A 1 562 ? 105.124 98.936  112.559 1.00 259.27 ? 561 GLU A CD  1 
ATOM   3130  O OE1 . GLU A 1 562 ? 106.004 99.164  111.665 1.00 291.40 ? 561 GLU A OE1 1 
ATOM   3131  O OE2 . GLU A 1 562 ? 103.932 99.325  112.480 1.00 316.54 ? 561 GLU A OE2 1 
ATOM   3132  N N   . ARG A 1 563 ? 108.552 98.460  115.505 1.00 127.14 ? 562 ARG A N   1 
ATOM   3133  C CA  . ARG A 1 563 ? 109.159 98.631  116.827 1.00 98.32  ? 562 ARG A CA  1 
ATOM   3134  C C   . ARG A 1 563 ? 108.036 98.959  117.798 1.00 86.74  ? 562 ARG A C   1 
ATOM   3135  O O   . ARG A 1 563 ? 107.159 99.698  117.453 1.00 113.43 ? 562 ARG A O   1 
ATOM   3136  C CB  . ARG A 1 563 ? 110.336 99.604  116.699 1.00 79.40  ? 562 ARG A CB  1 
ATOM   3137  C CG  . ARG A 1 563 ? 111.368 99.113  115.665 1.00 105.73 ? 562 ARG A CG  1 
ATOM   3138  C CD  . ARG A 1 563 ? 112.865 99.358  115.708 1.00 123.79 ? 562 ARG A CD  1 
ATOM   3139  N NE  . ARG A 1 563 ? 113.108 100.773 115.829 1.00 165.30 ? 562 ARG A NE  1 
ATOM   3140  C CZ  . ARG A 1 563 ? 114.312 101.303 115.931 1.00 249.60 ? 562 ARG A CZ  1 
ATOM   3141  N NH1 . ARG A 1 563 ? 114.440 102.601 115.692 1.00 295.06 ? 562 ARG A NH1 1 
ATOM   3142  N NH2 . ARG A 1 563 ? 115.353 100.528 116.229 1.00 216.05 ? 562 ARG A NH2 1 
ATOM   3143  N N   . PHE A 1 564 ? 108.029 98.372  118.992 1.00 89.72  ? 563 PHE A N   1 
ATOM   3144  C CA  . PHE A 1 564 ? 106.925 98.501  119.932 1.00 85.16  ? 563 PHE A CA  1 
ATOM   3145  C C   . PHE A 1 564 ? 107.454 99.069  121.236 1.00 89.52  ? 563 PHE A C   1 
ATOM   3146  O O   . PHE A 1 564 ? 108.339 98.505  121.847 1.00 104.09 ? 563 PHE A O   1 
ATOM   3147  C CB  . PHE A 1 564 ? 106.315 97.179  120.334 1.00 92.73  ? 563 PHE A CB  1 
ATOM   3148  C CG  . PHE A 1 564 ? 105.553 96.500  119.262 1.00 95.95  ? 563 PHE A CG  1 
ATOM   3149  C CD1 . PHE A 1 564 ? 106.237 95.887  118.242 1.00 105.72 ? 563 PHE A CD1 1 
ATOM   3150  C CD2 . PHE A 1 564 ? 104.179 96.481  119.314 1.00 101.37 ? 563 PHE A CD2 1 
ATOM   3151  C CE1 . PHE A 1 564 ? 105.515 95.249  117.265 1.00 137.97 ? 563 PHE A CE1 1 
ATOM   3152  C CE2 . PHE A 1 564 ? 103.447 95.838  118.357 1.00 105.11 ? 563 PHE A CE2 1 
ATOM   3153  C CZ  . PHE A 1 564 ? 104.121 95.230  117.329 1.00 155.08 ? 563 PHE A CZ  1 
ATOM   3154  N N   . LEU A 1 565 ? 106.889 100.174 121.658 1.00 92.50  ? 564 LEU A N   1 
ATOM   3155  C CA  . LEU A 1 565 ? 107.202 100.841 122.903 1.00 78.45  ? 564 LEU A CA  1 
ATOM   3156  C C   . LEU A 1 565 ? 106.047 100.488 123.834 1.00 62.87  ? 564 LEU A C   1 
ATOM   3157  O O   . LEU A 1 565 ? 104.933 100.648 123.459 1.00 62.47  ? 564 LEU A O   1 
ATOM   3158  C CB  . LEU A 1 565 ? 107.281 102.346 122.629 1.00 64.89  ? 564 LEU A CB  1 
ATOM   3159  C CG  . LEU A 1 565 ? 106.999 103.279 123.769 1.00 65.57  ? 564 LEU A CG  1 
ATOM   3160  C CD1 . LEU A 1 565 ? 108.154 103.171 124.761 1.00 93.39  ? 564 LEU A CD1 1 
ATOM   3161  C CD2 . LEU A 1 565 ? 106.880 104.675 123.232 1.00 70.55  ? 564 LEU A CD2 1 
ATOM   3162  N N   . VAL A 1 566 ? 106.356 100.025 125.031 1.00 61.36  ? 565 VAL A N   1 
ATOM   3163  C CA  . VAL A 1 566 ? 105.410 99.721  126.065 1.00 50.15  ? 565 VAL A CA  1 
ATOM   3164  C C   . VAL A 1 566 ? 105.646 100.713 127.182 1.00 63.99  ? 565 VAL A C   1 
ATOM   3165  O O   . VAL A 1 566 ? 106.771 101.057 127.506 1.00 113.12 ? 565 VAL A O   1 
ATOM   3166  C CB  . VAL A 1 566 ? 105.619 98.297  126.605 1.00 57.65  ? 565 VAL A CB  1 
ATOM   3167  C CG1 . VAL A 1 566 ? 104.590 98.029  127.696 1.00 58.56  ? 565 VAL A CG1 1 
ATOM   3168  C CG2 . VAL A 1 566 ? 105.511 97.239  125.515 1.00 58.58  ? 565 VAL A CG2 1 
ATOM   3169  N N   . VAL A 1 567 ? 104.585 101.180 127.797 1.00 62.80  ? 566 VAL A N   1 
ATOM   3170  C CA  . VAL A 1 567 ? 104.702 102.220 128.789 1.00 53.75  ? 566 VAL A CA  1 
ATOM   3171  C C   . VAL A 1 567 ? 103.731 101.811 129.869 1.00 50.41  ? 566 VAL A C   1 
ATOM   3172  O O   . VAL A 1 567 ? 102.550 101.983 129.677 1.00 62.34  ? 566 VAL A O   1 
ATOM   3173  C CB  . VAL A 1 567 ? 104.340 103.611 128.222 1.00 67.35  ? 566 VAL A CB  1 
ATOM   3174  C CG1 . VAL A 1 567 ? 104.452 104.680 129.300 1.00 63.76  ? 566 VAL A CG1 1 
ATOM   3175  C CG2 . VAL A 1 567 ? 105.093 103.956 126.926 1.00 67.22  ? 566 VAL A CG2 1 
ATOM   3176  N N   . LEU A 1 568 ? 104.231 101.316 130.983 1.00 49.20  ? 567 LEU A N   1 
ATOM   3177  C CA  . LEU A 1 568 ? 103.358 100.879 132.059 1.00 59.91  ? 567 LEU A CA  1 
ATOM   3178  C C   . LEU A 1 568 ? 103.413 101.879 133.211 1.00 69.13  ? 567 LEU A C   1 
ATOM   3179  O O   . LEU A 1 568 ? 104.504 102.150 133.700 1.00 53.60  ? 567 LEU A O   1 
ATOM   3180  C CB  . LEU A 1 568 ? 103.836 99.505  132.499 1.00 52.10  ? 567 LEU A CB  1 
ATOM   3181  C CG  . LEU A 1 568 ? 103.932 98.491  131.379 1.00 54.55  ? 567 LEU A CG  1 
ATOM   3182  C CD1 . LEU A 1 568 ? 105.002 97.460  131.701 1.00 43.99  ? 567 LEU A CD1 1 
ATOM   3183  C CD2 . LEU A 1 568 ? 102.625 97.812  131.175 1.00 89.52  ? 567 LEU A CD2 1 
ATOM   3184  N N   . ASN A 1 569 ? 102.285 102.435 133.652 1.00 52.13  ? 568 ASN A N   1 
ATOM   3185  C CA  . ASN A 1 569 ? 102.408 103.452 134.679 1.00 54.03  ? 568 ASN A CA  1 
ATOM   3186  C C   . ASN A 1 569 ? 102.094 102.807 135.980 1.00 47.14  ? 568 ASN A C   1 
ATOM   3187  O O   . ASN A 1 569 ? 100.942 102.794 136.358 1.00 46.87  ? 568 ASN A O   1 
ATOM   3188  C CB  . ASN A 1 569 ? 101.471 104.638 134.507 1.00 81.46  ? 568 ASN A CB  1 
ATOM   3189  C CG  . ASN A 1 569 ? 101.552 105.702 135.595 1.00 57.86  ? 568 ASN A CG  1 
ATOM   3190  O OD1 . ASN A 1 569 ? 102.505 105.824 136.324 1.00 57.63  ? 568 ASN A OD1 1 
ATOM   3191  N ND2 . ASN A 1 569 ? 100.531 106.513 135.737 1.00 65.12  ? 568 ASN A ND2 1 
ATOM   3192  N N   . PHE A 1 570 ? 103.131 102.315 136.671 1.00 49.64  ? 569 PHE A N   1 
ATOM   3193  C CA  . PHE A 1 570 ? 102.875 101.520 137.846 1.00 58.36  ? 569 PHE A CA  1 
ATOM   3194  C C   . PHE A 1 570 ? 102.440 102.365 139.043 1.00 74.55  ? 569 PHE A C   1 
ATOM   3195  O O   . PHE A 1 570 ? 101.545 101.943 139.783 1.00 75.23  ? 569 PHE A O   1 
ATOM   3196  C CB  . PHE A 1 570 ? 104.098 100.680 138.098 1.00 65.73  ? 569 PHE A CB  1 
ATOM   3197  C CG  . PHE A 1 570 ? 104.070 99.379  137.359 1.00 74.60  ? 569 PHE A CG  1 
ATOM   3198  C CD1 . PHE A 1 570 ? 103.103 98.419  137.633 1.00 54.81  ? 569 PHE A CD1 1 
ATOM   3199  C CD2 . PHE A 1 570 ? 105.052 99.122  136.425 1.00 86.38  ? 569 PHE A CD2 1 
ATOM   3200  C CE1 . PHE A 1 570 ? 103.164 97.219  136.963 1.00 63.76  ? 569 PHE A CE1 1 
ATOM   3201  C CE2 . PHE A 1 570 ? 105.074 97.934  135.727 1.00 71.28  ? 569 PHE A CE2 1 
ATOM   3202  C CZ  . PHE A 1 570 ? 104.124 96.991  136.002 1.00 84.94  ? 569 PHE A CZ  1 
ATOM   3203  N N   . GLY A 1 571 ? 103.065 103.513 139.234 1.00 79.36  ? 570 GLY A N   1 
ATOM   3204  C CA  . GLY A 1 571 ? 102.613 104.408 140.279 1.00 126.29 ? 570 GLY A CA  1 
ATOM   3205  C C   . GLY A 1 571 ? 101.153 104.903 140.141 1.00 87.56  ? 570 GLY A C   1 
ATOM   3206  O O   . GLY A 1 571 ? 100.646 105.020 139.027 1.00 45.17  ? 570 GLY A O   1 
ATOM   3207  N N   . ASP A 1 572 ? 100.549 105.265 141.300 1.00 73.42  ? 571 ASP A N   1 
ATOM   3208  C CA  . ASP A 1 572 ? 99.150  105.651 141.398 1.00 73.51  ? 571 ASP A CA  1 
ATOM   3209  C C   . ASP A 1 572 ? 98.837  107.091 141.029 1.00 58.82  ? 571 ASP A C   1 
ATOM   3210  O O   . ASP A 1 572 ? 97.750  107.551 141.309 1.00 63.92  ? 571 ASP A O   1 
ATOM   3211  C CB  . ASP A 1 572 ? 98.565  105.425 142.790 1.00 81.80  ? 571 ASP A CB  1 
ATOM   3212  C CG  . ASP A 1 572 ? 99.262  106.185 143.877 1.00 114.69 ? 571 ASP A CG  1 
ATOM   3213  O OD1 . ASP A 1 572 ? 100.368 105.752 144.152 1.00 234.30 ? 571 ASP A OD1 1 
ATOM   3214  O OD2 . ASP A 1 572 ? 98.718  107.177 144.427 1.00 177.64 ? 571 ASP A OD2 1 
ATOM   3215  N N   . VAL A 1 573 ? 99.736  107.798 140.376 1.00 77.96  ? 572 VAL A N   1 
ATOM   3216  C CA  . VAL A 1 573 ? 99.557  109.198 140.078 1.00 54.95  ? 572 VAL A CA  1 
ATOM   3217  C C   . VAL A 1 573 ? 99.687  109.328 138.586 1.00 57.24  ? 572 VAL A C   1 
ATOM   3218  O O   . VAL A 1 573 ? 100.698 108.840 138.028 1.00 68.53  ? 572 VAL A O   1 
ATOM   3219  C CB  . VAL A 1 573 ? 100.717 109.971 140.697 1.00 71.65  ? 572 VAL A CB  1 
ATOM   3220  C CG1 . VAL A 1 573 ? 100.162 111.376 140.727 1.00 102.04 ? 572 VAL A CG1 1 
ATOM   3221  C CG2 . VAL A 1 573 ? 101.226 109.407 142.063 1.00 91.57  ? 572 VAL A CG2 1 
ATOM   3222  N N   . GLY A 1 574 ? 98.745  109.980 137.935 1.00 52.22  ? 573 GLY A N   1 
ATOM   3223  C CA  . GLY A 1 574 ? 98.905  110.125 136.490 1.00 77.84  ? 573 GLY A CA  1 
ATOM   3224  C C   . GLY A 1 574 ? 100.074 111.028 136.054 1.00 71.15  ? 573 GLY A C   1 
ATOM   3225  O O   . GLY A 1 574 ? 100.460 111.924 136.807 1.00 81.21  ? 573 GLY A O   1 
ATOM   3226  N N   . LEU A 1 575 ? 100.589 110.850 134.818 1.00 73.08  ? 574 LEU A N   1 
ATOM   3227  C CA  . LEU A 1 575 ? 101.534 111.815 134.271 1.00 80.81  ? 574 LEU A CA  1 
ATOM   3228  C C   . LEU A 1 575 ? 100.875 112.751 133.266 1.00 79.12  ? 574 LEU A C   1 
ATOM   3229  O O   . LEU A 1 575 ? 99.922  112.405 132.555 1.00 101.20 ? 574 LEU A O   1 
ATOM   3230  C CB  . LEU A 1 575 ? 102.682 111.088 133.620 1.00 77.95  ? 574 LEU A CB  1 
ATOM   3231  C CG  . LEU A 1 575 ? 103.420 110.140 134.566 1.00 94.77  ? 574 LEU A CG  1 
ATOM   3232  C CD1 . LEU A 1 575 ? 104.692 109.719 133.901 1.00 109.08 ? 574 LEU A CD1 1 
ATOM   3233  C CD2 . LEU A 1 575 ? 103.706 110.718 135.957 1.00 79.81  ? 574 LEU A CD2 1 
ATOM   3234  N N   . SER A 1 576 ? 101.401 113.973 133.234 1.00 70.71  ? 575 SER A N   1 
ATOM   3235  C CA  . SER A 1 576 ? 100.646 115.091 132.703 1.00 90.58  ? 575 SER A CA  1 
ATOM   3236  C C   . SER A 1 576 ? 101.500 115.910 131.717 1.00 78.62  ? 575 SER A C   1 
ATOM   3237  O O   . SER A 1 576 ? 101.131 117.027 131.309 1.00 96.23  ? 575 SER A O   1 
ATOM   3238  C CB  . SER A 1 576 ? 100.004 115.856 133.878 1.00 108.70 ? 575 SER A CB  1 
ATOM   3239  O OG  . SER A 1 576 ? 99.098  116.794 133.323 1.00 199.83 ? 575 SER A OG  1 
ATOM   3240  N N   . ALA A 1 577 ? 102.644 115.327 131.318 1.00 66.28  ? 576 ALA A N   1 
ATOM   3241  C CA  . ALA A 1 577 ? 103.726 116.119 130.725 1.00 86.98  ? 576 ALA A CA  1 
ATOM   3242  C C   . ALA A 1 577 ? 104.549 115.262 129.777 1.00 86.70  ? 576 ALA A C   1 
ATOM   3243  O O   . ALA A 1 577 ? 105.710 115.501 129.510 1.00 73.28  ? 576 ALA A O   1 
ATOM   3244  C CB  . ALA A 1 577 ? 104.580 116.759 131.818 1.00 67.32  ? 576 ALA A CB  1 
ATOM   3245  N N   . GLY A 1 578 ? 103.886 114.269 129.225 1.00 87.24  ? 577 GLY A N   1 
ATOM   3246  C CA  . GLY A 1 578 ? 104.526 113.434 128.239 1.00 102.97 ? 577 GLY A CA  1 
ATOM   3247  C C   . GLY A 1 578 ? 105.474 112.422 128.819 1.00 67.48  ? 577 GLY A C   1 
ATOM   3248  O O   . GLY A 1 578 ? 105.723 112.384 130.012 1.00 116.70 ? 577 GLY A O   1 
ATOM   3249  N N   . LEU A 1 579 ? 105.943 111.562 127.903 1.00 69.99  ? 578 LEU A N   1 
ATOM   3250  C CA  . LEU A 1 579 ? 107.223 110.886 128.027 1.00 76.73  ? 578 LEU A CA  1 
ATOM   3251  C C   . LEU A 1 579 ? 108.255 111.970 127.996 1.00 74.00  ? 578 LEU A C   1 
ATOM   3252  O O   . LEU A 1 579 ? 108.084 112.987 127.332 1.00 101.56 ? 578 LEU A O   1 
ATOM   3253  C CB  . LEU A 1 579 ? 107.498 109.848 126.950 1.00 69.17  ? 578 LEU A CB  1 
ATOM   3254  C CG  . LEU A 1 579 ? 106.807 108.496 127.267 1.00 86.77  ? 578 LEU A CG  1 
ATOM   3255  C CD1 . LEU A 1 579 ? 105.384 108.629 127.889 1.00 63.44  ? 578 LEU A CD1 1 
ATOM   3256  C CD2 . LEU A 1 579 ? 106.798 107.504 126.057 1.00 72.64  ? 578 LEU A CD2 1 
ATOM   3257  N N   . GLN A 1 580 ? 109.321 111.712 128.765 1.00 66.70  ? 579 GLN A N   1 
ATOM   3258  C CA  . GLN A 1 580 ? 110.468 112.550 128.622 1.00 99.32  ? 579 GLN A CA  1 
ATOM   3259  C C   . GLN A 1 580 ? 111.637 111.635 128.867 1.00 85.62  ? 579 GLN A C   1 
ATOM   3260  O O   . GLN A 1 580 ? 112.135 111.678 129.964 1.00 64.71  ? 579 GLN A O   1 
ATOM   3261  C CB  . GLN A 1 580 ? 110.341 113.887 129.372 1.00 89.63  ? 579 GLN A CB  1 
ATOM   3262  C CG  . GLN A 1 580 ? 109.394 113.972 130.515 1.00 92.65  ? 579 GLN A CG  1 
ATOM   3263  C CD  . GLN A 1 580 ? 109.350 115.337 131.225 1.00 106.08 ? 579 GLN A CD  1 
ATOM   3264  O OE1 . GLN A 1 580 ? 108.310 115.835 131.691 1.00 47.45  ? 579 GLN A OE1 1 
ATOM   3265  N NE2 . GLN A 1 580 ? 110.514 115.973 131.361 1.00 100.22 ? 579 GLN A NE2 1 
ATOM   3266  N N   . ALA A 1 581 ? 112.000 110.888 127.771 1.00 104.69 ? 580 ALA A N   1 
ATOM   3267  C CA  . ALA A 1 581 ? 113.063 109.901 127.728 1.00 120.19 ? 580 ALA A CA  1 
ATOM   3268  C C   . ALA A 1 581 ? 114.436 110.558 127.881 1.00 137.52 ? 580 ALA A C   1 
ATOM   3269  O O   . ALA A 1 581 ? 114.883 111.325 127.024 1.00 111.62 ? 580 ALA A O   1 
ATOM   3270  C CB  . ALA A 1 581 ? 112.973 109.129 126.440 1.00 167.65 ? 580 ALA A CB  1 
ATOM   3271  N N   . SER A 1 582 ? 115.113 110.244 128.991 1.00 177.91 ? 581 SER A N   1 
ATOM   3272  C CA  . SER A 1 582 ? 116.552 110.406 129.076 1.00 224.48 ? 581 SER A CA  1 
ATOM   3273  C C   . SER A 1 582 ? 117.212 109.202 128.420 1.00 272.32 ? 581 SER A C   1 
ATOM   3274  O O   . SER A 1 582 ? 116.813 108.070 128.713 1.00 245.41 ? 581 SER A O   1 
ATOM   3275  C CB  . SER A 1 582 ? 116.983 110.547 130.514 1.00 308.73 ? 581 SER A CB  1 
ATOM   3276  O OG  . SER A 1 582 ? 118.396 110.601 130.641 1.00 377.33 ? 581 SER A OG  1 
ATOM   3277  N N   . ASP A 1 583 ? 118.212 109.452 127.549 1.00 286.24 ? 582 ASP A N   1 
ATOM   3278  C CA  . ASP A 1 583 ? 119.312 108.523 127.285 1.00 354.23 ? 582 ASP A CA  1 
ATOM   3279  C C   . ASP A 1 583 ? 118.826 107.211 126.660 1.00 295.14 ? 582 ASP A C   1 
ATOM   3280  O O   . ASP A 1 583 ? 119.044 106.109 127.193 1.00 322.98 ? 582 ASP A O   1 
ATOM   3281  C CB  . ASP A 1 583 ? 120.125 108.240 128.558 1.00 492.87 ? 582 ASP A CB  1 
ATOM   3282  C CG  . ASP A 1 583 ? 121.398 107.422 128.364 1.00 562.52 ? 582 ASP A CG  1 
ATOM   3283  O OD1 . ASP A 1 583 ? 121.889 107.338 127.216 1.00 566.00 ? 582 ASP A OD1 1 
ATOM   3284  O OD2 . ASP A 1 583 ? 121.881 106.863 129.366 1.00 619.71 ? 582 ASP A OD2 1 
ATOM   3285  N N   . LEU A 1 584 ? 118.176 107.336 125.507 1.00 217.33 ? 583 LEU A N   1 
ATOM   3286  C CA  . LEU A 1 584 ? 117.846 106.169 124.708 1.00 245.95 ? 583 LEU A CA  1 
ATOM   3287  C C   . LEU A 1 584 ? 119.087 105.648 123.999 1.00 264.55 ? 583 LEU A C   1 
ATOM   3288  O O   . LEU A 1 584 ? 119.938 106.456 123.609 1.00 187.12 ? 583 LEU A O   1 
ATOM   3289  C CB  . LEU A 1 584 ? 116.782 106.555 123.697 1.00 219.16 ? 583 LEU A CB  1 
ATOM   3290  C CG  . LEU A 1 584 ? 115.405 106.649 124.340 1.00 167.77 ? 583 LEU A CG  1 
ATOM   3291  C CD1 . LEU A 1 584 ? 114.591 107.717 123.662 1.00 238.43 ? 583 LEU A CD1 1 
ATOM   3292  C CD2 . LEU A 1 584 ? 114.711 105.314 124.273 1.00 93.24  ? 583 LEU A CD2 1 
ATOM   3293  N N   . PRO A 1 585 ? 119.207 104.302 123.815 1.00 313.86 ? 584 PRO A N   1 
ATOM   3294  C CA  . PRO A 1 585 ? 120.222 103.745 122.919 1.00 297.73 ? 584 PRO A CA  1 
ATOM   3295  C C   . PRO A 1 585 ? 120.095 104.368 121.524 1.00 236.01 ? 584 PRO A C   1 
ATOM   3296  O O   . PRO A 1 585 ? 118.979 104.546 121.020 1.00 252.46 ? 584 PRO A O   1 
ATOM   3297  C CB  . PRO A 1 585 ? 119.949 102.224 122.911 1.00 346.73 ? 584 PRO A CB  1 
ATOM   3298  C CG  . PRO A 1 585 ? 119.009 101.929 124.088 1.00 336.02 ? 584 PRO A CG  1 
ATOM   3299  C CD  . PRO A 1 585 ? 118.380 103.255 124.458 1.00 312.18 ? 584 PRO A CD  1 
ATOM   3300  N N   . ALA A 1 586 ? 121.235 104.682 120.884 1.00 292.83 ? 585 ALA A N   1 
ATOM   3301  C CA  . ALA A 1 586 ? 121.243 105.478 119.659 1.00 313.57 ? 585 ALA A CA  1 
ATOM   3302  C C   . ALA A 1 586 ? 120.590 104.734 118.483 1.00 268.98 ? 585 ALA A C   1 
ATOM   3303  O O   . ALA A 1 586 ? 120.099 105.372 117.548 1.00 162.84 ? 585 ALA A O   1 
ATOM   3304  C CB  . ALA A 1 586 ? 122.664 105.887 119.338 1.00 370.59 ? 585 ALA A CB  1 
ATOM   3305  N N   . SER A 1 587 ? 120.588 103.388 118.541 1.00 294.23 ? 586 SER A N   1 
ATOM   3306  C CA  . SER A 1 587 ? 119.914 102.512 117.589 1.00 312.94 ? 586 SER A CA  1 
ATOM   3307  C C   . SER A 1 587 ? 118.387 102.501 117.709 1.00 271.42 ? 586 SER A C   1 
ATOM   3308  O O   . SER A 1 587 ? 117.739 102.057 116.767 1.00 227.30 ? 586 SER A O   1 
ATOM   3309  C CB  . SER A 1 587 ? 120.433 101.097 117.744 1.00 331.68 ? 586 SER A CB  1 
ATOM   3310  O OG  . SER A 1 587 ? 120.204 100.612 119.060 1.00 249.71 ? 586 SER A OG  1 
ATOM   3311  N N   . ALA A 1 588 ? 117.832 102.962 118.843 1.00 278.00 ? 587 ALA A N   1 
ATOM   3312  C CA  . ALA A 1 588 ? 116.450 102.680 119.233 1.00 196.01 ? 587 ALA A CA  1 
ATOM   3313  C C   . ALA A 1 588 ? 115.652 103.940 119.571 1.00 179.09 ? 587 ALA A C   1 
ATOM   3314  O O   . ALA A 1 588 ? 114.682 103.848 120.327 1.00 224.63 ? 587 ALA A O   1 
ATOM   3315  C CB  . ALA A 1 588 ? 116.475 101.751 120.407 1.00 205.19 ? 587 ALA A CB  1 
ATOM   3316  N N   . SER A 1 589 ? 116.062 105.102 119.028 1.00 246.11 ? 588 SER A N   1 
ATOM   3317  C CA  . SER A 1 589 ? 115.544 106.400 119.452 1.00 224.44 ? 588 SER A CA  1 
ATOM   3318  C C   . SER A 1 589 ? 114.028 106.454 119.251 1.00 180.22 ? 588 SER A C   1 
ATOM   3319  O O   . SER A 1 589 ? 113.489 105.911 118.277 1.00 117.23 ? 588 SER A O   1 
ATOM   3320  C CB  . SER A 1 589 ? 116.253 107.537 118.738 1.00 256.50 ? 588 SER A CB  1 
ATOM   3321  O OG  . SER A 1 589 ? 116.185 107.373 117.323 1.00 320.55 ? 588 SER A OG  1 
ATOM   3322  N N   . LEU A 1 590 ? 113.352 107.127 120.193 1.00 177.85 ? 589 LEU A N   1 
ATOM   3323  C CA  . LEU A 1 590 ? 111.916 107.319 120.114 1.00 146.49 ? 589 LEU A CA  1 
ATOM   3324  C C   . LEU A 1 590 ? 111.546 108.265 118.983 1.00 159.11 ? 589 LEU A C   1 
ATOM   3325  O O   . LEU A 1 590 ? 112.243 109.254 118.708 1.00 168.97 ? 589 LEU A O   1 
ATOM   3326  C CB  . LEU A 1 590 ? 111.378 107.997 121.371 1.00 167.15 ? 589 LEU A CB  1 
ATOM   3327  C CG  . LEU A 1 590 ? 111.151 107.149 122.610 1.00 133.21 ? 589 LEU A CG  1 
ATOM   3328  C CD1 . LEU A 1 590 ? 110.474 107.998 123.676 1.00 169.27 ? 589 LEU A CD1 1 
ATOM   3329  C CD2 . LEU A 1 590 ? 110.287 105.981 122.303 1.00 106.32 ? 589 LEU A CD2 1 
ATOM   3330  N N   . PRO A 1 591 ? 110.389 108.009 118.333 1.00 151.61 ? 590 PRO A N   1 
ATOM   3331  C CA  . PRO A 1 591 ? 109.857 108.936 117.332 1.00 164.64 ? 590 PRO A CA  1 
ATOM   3332  C C   . PRO A 1 591 ? 109.229 110.175 117.958 1.00 127.67 ? 590 PRO A C   1 
ATOM   3333  O O   . PRO A 1 591 ? 109.113 110.272 119.183 1.00 166.50 ? 590 PRO A O   1 
ATOM   3334  C CB  . PRO A 1 591 ? 108.817 108.042 116.649 1.00 163.02 ? 590 PRO A CB  1 
ATOM   3335  C CG  . PRO A 1 591 ? 108.282 107.249 117.786 1.00 127.27 ? 590 PRO A CG  1 
ATOM   3336  C CD  . PRO A 1 591 ? 109.525 106.828 118.534 1.00 117.37 ? 590 PRO A CD  1 
ATOM   3337  N N   . ALA A 1 592 ? 108.826 111.116 117.106 1.00 147.54 ? 591 ALA A N   1 
ATOM   3338  C CA  . ALA A 1 592 ? 108.031 112.251 117.560 1.00 215.06 ? 591 ALA A CA  1 
ATOM   3339  C C   . ALA A 1 592 ? 106.606 111.819 117.910 1.00 126.98 ? 591 ALA A C   1 
ATOM   3340  O O   . ALA A 1 592 ? 105.997 112.429 118.802 1.00 117.87 ? 591 ALA A O   1 
ATOM   3341  C CB  . ALA A 1 592 ? 108.038 113.333 116.504 1.00 297.55 ? 591 ALA A CB  1 
ATOM   3342  N N   . LYS A 1 593 ? 106.110 110.797 117.183 1.00 115.41 ? 592 LYS A N   1 
ATOM   3343  C CA  . LYS A 1 593 ? 104.763 110.248 117.333 1.00 120.56 ? 592 LYS A CA  1 
ATOM   3344  C C   . LYS A 1 593 ? 104.752 108.769 116.966 1.00 122.33 ? 592 LYS A C   1 
ATOM   3345  O O   . LYS A 1 593 ? 105.597 108.307 116.195 1.00 173.96 ? 592 LYS A O   1 
ATOM   3346  C CB  . LYS A 1 593 ? 103.717 110.873 116.405 1.00 147.86 ? 592 LYS A CB  1 
ATOM   3347  C CG  . LYS A 1 593 ? 103.562 112.385 116.413 1.00 208.47 ? 592 LYS A CG  1 
ATOM   3348  C CD  . LYS A 1 593 ? 102.235 112.795 115.751 1.00 206.78 ? 592 LYS A CD  1 
ATOM   3349  C CE  . LYS A 1 593 ? 102.088 114.285 115.547 1.00 273.69 ? 592 LYS A CE  1 
ATOM   3350  N NZ  . LYS A 1 593 ? 102.877 114.762 114.384 1.00 335.03 ? 592 LYS A NZ  1 
ATOM   3351  N N   . ALA A 1 594 ? 103.769 108.056 117.508 1.00 106.26 ? 593 ALA A N   1 
ATOM   3352  C CA  . ALA A 1 594 ? 103.689 106.597 117.422 1.00 133.17 ? 593 ALA A CA  1 
ATOM   3353  C C   . ALA A 1 594 ? 102.230 106.178 117.593 1.00 129.88 ? 593 ALA A C   1 
ATOM   3354  O O   . ALA A 1 594 ? 101.452 106.874 118.286 1.00 105.88 ? 593 ALA A O   1 
ATOM   3355  C CB  . ALA A 1 594 ? 104.538 105.923 118.490 1.00 165.25 ? 593 ALA A CB  1 
ATOM   3356  N N   . ASP A 1 595 ? 101.867 105.043 116.961 1.00 133.71 ? 594 ASP A N   1 
ATOM   3357  C CA  . ASP A 1 595 ? 100.466 104.636 116.790 1.00 130.27 ? 594 ASP A CA  1 
ATOM   3358  C C   . ASP A 1 595 ? 99.965  103.835 117.976 1.00 84.93  ? 594 ASP A C   1 
ATOM   3359  O O   . ASP A 1 595 ? 100.501 102.725 118.181 1.00 120.16 ? 594 ASP A O   1 
ATOM   3360  C CB  . ASP A 1 595 ? 100.284 103.723 115.571 1.00 228.11 ? 594 ASP A CB  1 
ATOM   3361  C CG  . ASP A 1 595 ? 100.700 104.309 114.226 1.00 355.58 ? 594 ASP A CG  1 
ATOM   3362  O OD1 . ASP A 1 595 ? 100.981 105.524 114.157 1.00 401.76 ? 594 ASP A OD1 1 
ATOM   3363  O OD2 . ASP A 1 595 ? 100.744 103.532 113.246 1.00 410.49 ? 594 ASP A OD2 1 
ATOM   3364  N N   . LEU A 1 596 ? 98.994  104.359 118.758 1.00 74.06  ? 595 LEU A N   1 
ATOM   3365  C CA  . LEU A 1 596 ? 98.437  103.596 119.878 1.00 93.11  ? 595 LEU A CA  1 
ATOM   3366  C C   . LEU A 1 596 ? 97.729  102.317 119.406 1.00 80.40  ? 595 LEU A C   1 
ATOM   3367  O O   . LEU A 1 596 ? 96.647  102.361 118.879 1.00 143.97 ? 595 LEU A O   1 
ATOM   3368  C CB  . LEU A 1 596 ? 97.479  104.480 120.658 1.00 78.53  ? 595 LEU A CB  1 
ATOM   3369  C CG  . LEU A 1 596 ? 96.705  103.827 121.812 1.00 99.69  ? 595 LEU A CG  1 
ATOM   3370  C CD1 . LEU A 1 596 ? 97.566  103.198 122.825 1.00 110.90 ? 595 LEU A CD1 1 
ATOM   3371  C CD2 . LEU A 1 596 ? 95.920  104.858 122.607 1.00 118.61 ? 595 LEU A CD2 1 
ATOM   3372  N N   . LEU A 1 597 ? 98.346  101.169 119.609 1.00 81.71  ? 596 LEU A N   1 
ATOM   3373  C CA  . LEU A 1 597 ? 97.774  99.890  119.269 1.00 102.54 ? 596 LEU A CA  1 
ATOM   3374  C C   . LEU A 1 597 ? 96.759  99.408  120.310 1.00 100.53 ? 596 LEU A C   1 
ATOM   3375  O O   . LEU A 1 597 ? 95.842  98.675  119.958 1.00 158.94 ? 596 LEU A O   1 
ATOM   3376  C CB  . LEU A 1 597 ? 98.942  98.917  119.143 1.00 131.88 ? 596 LEU A CB  1 
ATOM   3377  C CG  . LEU A 1 597 ? 98.596  97.468  118.823 1.00 149.40 ? 596 LEU A CG  1 
ATOM   3378  C CD1 . LEU A 1 597 ? 97.895  97.389  117.478 1.00 245.51 ? 596 LEU A CD1 1 
ATOM   3379  C CD2 . LEU A 1 597 ? 99.877  96.675  118.789 1.00 163.98 ? 596 LEU A CD2 1 
ATOM   3380  N N   . LEU A 1 598 ? 96.944  99.749  121.571 1.00 103.55 ? 597 LEU A N   1 
ATOM   3381  C CA  . LEU A 1 598 ? 95.941  99.549  122.579 1.00 111.96 ? 597 LEU A CA  1 
ATOM   3382  C C   . LEU A 1 598 ? 96.360  100.227 123.865 1.00 99.80  ? 597 LEU A C   1 
ATOM   3383  O O   . LEU A 1 598 ? 97.520  100.444 124.108 1.00 77.76  ? 597 LEU A O   1 
ATOM   3384  C CB  . LEU A 1 598 ? 95.730  98.066  122.884 1.00 125.44 ? 597 LEU A CB  1 
ATOM   3385  C CG  . LEU A 1 598 ? 96.749  97.353  123.773 1.00 88.01  ? 597 LEU A CG  1 
ATOM   3386  C CD1 . LEU A 1 598 ? 96.375  97.434  125.254 1.00 114.29 ? 597 LEU A CD1 1 
ATOM   3387  C CD2 . LEU A 1 598 ? 96.812  95.895  123.430 1.00 130.55 ? 597 LEU A CD2 1 
ATOM   3388  N N   . SER A 1 599 ? 95.377  100.553 124.689 1.00 104.85 ? 598 SER A N   1 
ATOM   3389  C CA  . SER A 1 599 ? 95.609  100.976 126.053 1.00 79.72  ? 598 SER A CA  1 
ATOM   3390  C C   . SER A 1 599 ? 94.839  100.035 126.970 1.00 71.18  ? 598 SER A C   1 
ATOM   3391  O O   . SER A 1 599 ? 93.811  99.475  126.641 1.00 88.02  ? 598 SER A O   1 
ATOM   3392  C CB  . SER A 1 599 ? 95.196  102.402 126.283 1.00 97.98  ? 598 SER A CB  1 
ATOM   3393  O OG  . SER A 1 599 ? 95.227  102.734 127.662 1.00 74.91  ? 598 SER A OG  1 
ATOM   3394  N N   . THR A 1 600 ? 95.387  99.874  128.159 1.00 100.34 ? 599 THR A N   1 
ATOM   3395  C CA  . THR A 1 600 ? 94.767  99.203  129.290 1.00 80.31  ? 599 THR A CA  1 
ATOM   3396  C C   . THR A 1 600 ? 93.496  99.923  129.701 1.00 93.94  ? 599 THR A C   1 
ATOM   3397  O O   . THR A 1 600 ? 92.728  99.349  130.450 1.00 114.65 ? 599 THR A O   1 
ATOM   3398  C CB  . THR A 1 600 ? 95.859  99.161  130.389 1.00 99.15  ? 599 THR A CB  1 
ATOM   3399  O OG1 . THR A 1 600 ? 96.659  98.030  130.030 1.00 55.25  ? 599 THR A OG1 1 
ATOM   3400  C CG2 . THR A 1 600 ? 95.403  99.185  131.845 1.00 153.75 ? 599 THR A CG2 1 
ATOM   3401  N N   . GLN A 1 601 ? 93.271  101.183 129.264 1.00 103.90 ? 600 GLN A N   1 
ATOM   3402  C CA  . GLN A 1 601 ? 92.086  101.909 129.680 1.00 175.16 ? 600 GLN A CA  1 
ATOM   3403  C C   . GLN A 1 601 ? 91.167  102.266 128.502 1.00 211.14 ? 600 GLN A C   1 
ATOM   3404  O O   . GLN A 1 601 ? 91.595  102.504 127.372 1.00 179.88 ? 600 GLN A O   1 
ATOM   3405  C CB  . GLN A 1 601 ? 92.530  103.133 130.471 1.00 131.05 ? 600 GLN A CB  1 
ATOM   3406  C CG  . GLN A 1 601 ? 93.115  102.792 131.829 1.00 164.68 ? 600 GLN A CG  1 
ATOM   3407  C CD  . GLN A 1 601 ? 92.869  103.880 132.856 1.00 244.74 ? 600 GLN A CD  1 
ATOM   3408  O OE1 . GLN A 1 601 ? 92.740  105.067 132.542 1.00 278.10 ? 600 GLN A OE1 1 
ATOM   3409  N NE2 . GLN A 1 601 ? 92.797  103.475 134.116 1.00 321.55 ? 600 GLN A NE2 1 
ATOM   3410  N N   . PRO A 1 602 ? 89.838  102.304 128.753 1.00 188.63 ? 601 PRO A N   1 
ATOM   3411  C CA  . PRO A 1 602 ? 88.912  102.848 127.762 1.00 185.06 ? 601 PRO A CA  1 
ATOM   3412  C C   . PRO A 1 602 ? 89.053  104.363 127.608 1.00 197.91 ? 601 PRO A C   1 
ATOM   3413  O O   . PRO A 1 602 ? 89.676  105.044 128.424 1.00 248.52 ? 601 PRO A O   1 
ATOM   3414  C CB  . PRO A 1 602 ? 87.548  102.494 128.379 1.00 258.45 ? 601 PRO A CB  1 
ATOM   3415  C CG  . PRO A 1 602 ? 87.804  102.461 129.882 1.00 209.12 ? 601 PRO A CG  1 
ATOM   3416  C CD  . PRO A 1 602 ? 89.170  101.837 129.993 1.00 146.99 ? 601 PRO A CD  1 
ATOM   3417  N N   . GLY A 1 603 ? 88.443  104.893 126.551 1.00 206.05 ? 602 GLY A N   1 
ATOM   3418  C CA  . GLY A 1 603 ? 88.398  106.332 126.321 1.00 224.48 ? 602 GLY A CA  1 
ATOM   3419  C C   . GLY A 1 603 ? 89.637  106.859 125.595 1.00 211.13 ? 602 GLY A C   1 
ATOM   3420  O O   . GLY A 1 603 ? 89.987  108.037 125.737 1.00 256.39 ? 602 GLY A O   1 
ATOM   3421  N N   . ARG A 1 604 ? 90.270  105.975 124.806 1.00 151.28 ? 603 ARG A N   1 
ATOM   3422  C CA  . ARG A 1 604 ? 91.432  106.305 123.994 1.00 174.50 ? 603 ARG A CA  1 
ATOM   3423  C C   . ARG A 1 604 ? 91.164  106.077 122.509 1.00 209.77 ? 603 ARG A C   1 
ATOM   3424  O O   . ARG A 1 604 ? 90.344  105.225 122.139 1.00 215.45 ? 603 ARG A O   1 
ATOM   3425  C CB  . ARG A 1 604 ? 92.593  105.398 124.392 1.00 203.17 ? 603 ARG A CB  1 
ATOM   3426  C CG  . ARG A 1 604 ? 93.255  105.773 125.705 1.00 204.68 ? 603 ARG A CG  1 
ATOM   3427  C CD  . ARG A 1 604 ? 94.059  107.040 125.534 1.00 181.32 ? 603 ARG A CD  1 
ATOM   3428  N NE  . ARG A 1 604 ? 94.782  107.303 126.746 1.00 213.77 ? 603 ARG A NE  1 
ATOM   3429  C CZ  . ARG A 1 604 ? 95.757  108.184 126.873 1.00 230.81 ? 603 ARG A CZ  1 
ATOM   3430  N NH1 . ARG A 1 604 ? 96.326  108.318 128.046 1.00 226.50 ? 603 ARG A NH1 1 
ATOM   3431  N NH2 . ARG A 1 604 ? 96.166  108.938 125.869 1.00 249.54 ? 603 ARG A NH2 1 
ATOM   3432  N N   . GLU A 1 605 ? 91.885  106.838 121.666 1.00 215.16 ? 604 GLU A N   1 
ATOM   3433  C CA  . GLU A 1 605 ? 91.666  106.862 120.227 1.00 242.14 ? 604 GLU A CA  1 
ATOM   3434  C C   . GLU A 1 605 ? 92.511  105.780 119.546 1.00 193.65 ? 604 GLU A C   1 
ATOM   3435  O O   . GLU A 1 605 ? 93.469  106.085 118.835 1.00 174.14 ? 604 GLU A O   1 
ATOM   3436  C CB  . GLU A 1 605 ? 91.983  108.262 119.700 1.00 331.35 ? 604 GLU A CB  1 
ATOM   3437  C CG  . GLU A 1 605 ? 91.011  109.336 120.177 1.00 432.25 ? 604 GLU A CG  1 
ATOM   3438  C CD  . GLU A 1 605 ? 91.358  110.759 119.766 1.00 562.97 ? 604 GLU A CD  1 
ATOM   3439  O OE1 . GLU A 1 605 ? 91.630  110.973 118.568 1.00 630.00 ? 604 GLU A OE1 1 
ATOM   3440  O OE2 . GLU A 1 605 ? 91.351  111.656 120.644 1.00 639.85 ? 604 GLU A OE2 1 
ATOM   3441  N N   . GLU A 1 606 ? 92.148  104.504 119.758 1.00 149.43 ? 605 GLU A N   1 
ATOM   3442  C CA  . GLU A 1 606 ? 93.031  103.404 119.379 1.00 181.48 ? 605 GLU A CA  1 
ATOM   3443  C C   . GLU A 1 606 ? 93.167  103.367 117.848 1.00 182.33 ? 605 GLU A C   1 
ATOM   3444  O O   . GLU A 1 606 ? 92.194  103.519 117.113 1.00 215.05 ? 605 GLU A O   1 
ATOM   3445  C CB  . GLU A 1 606 ? 92.600  102.057 119.973 1.00 212.76 ? 605 GLU A CB  1 
ATOM   3446  C CG  . GLU A 1 606 ? 92.483  102.113 121.487 1.00 235.18 ? 605 GLU A CG  1 
ATOM   3447  C CD  . GLU A 1 606 ? 92.397  100.803 122.262 1.00 280.51 ? 605 GLU A CD  1 
ATOM   3448  O OE1 . GLU A 1 606 ? 91.841  99.772  121.756 1.00 399.37 ? 605 GLU A OE1 1 
ATOM   3449  O OE2 . GLU A 1 606 ? 92.884  100.801 123.405 1.00 207.65 ? 605 GLU A OE2 1 
ATOM   3450  N N   . GLY A 1 607 ? 94.415  103.172 117.390 1.00 179.06 ? 606 GLY A N   1 
ATOM   3451  C CA  . GLY A 1 607 ? 94.816  103.331 116.005 1.00 149.18 ? 606 GLY A CA  1 
ATOM   3452  C C   . GLY A 1 607 ? 95.489  104.672 115.725 1.00 156.90 ? 606 GLY A C   1 
ATOM   3453  O O   . GLY A 1 607 ? 96.303  104.724 114.794 1.00 182.33 ? 606 GLY A O   1 
ATOM   3454  N N   . SER A 1 608 ? 95.154  105.737 116.490 1.00 156.84 ? 607 SER A N   1 
ATOM   3455  C CA  . SER A 1 608 ? 95.628  107.086 116.177 1.00 185.34 ? 607 SER A CA  1 
ATOM   3456  C C   . SER A 1 608 ? 97.082  107.286 116.602 1.00 177.57 ? 607 SER A C   1 
ATOM   3457  O O   . SER A 1 608 ? 97.554  106.654 117.559 1.00 255.27 ? 607 SER A O   1 
ATOM   3458  C CB  . SER A 1 608 ? 94.786  108.139 116.833 1.00 220.10 ? 607 SER A CB  1 
ATOM   3459  O OG  . SER A 1 608 ? 94.962  108.121 118.252 1.00 201.60 ? 607 SER A OG  1 
ATOM   3460  N N   . PRO A 1 609 ? 97.857  108.158 115.920 1.00 146.57 ? 608 PRO A N   1 
ATOM   3461  C CA  . PRO A 1 609 ? 99.169  108.581 116.415 1.00 193.65 ? 608 PRO A CA  1 
ATOM   3462  C C   . PRO A 1 609 ? 99.063  109.546 117.598 1.00 180.71 ? 608 PRO A C   1 
ATOM   3463  O O   . PRO A 1 609 ? 98.193  110.421 117.620 1.00 161.96 ? 608 PRO A O   1 
ATOM   3464  C CB  . PRO A 1 609 ? 99.846  109.221 115.196 1.00 194.37 ? 608 PRO A CB  1 
ATOM   3465  C CG  . PRO A 1 609 ? 98.691  109.701 114.374 1.00 228.92 ? 608 PRO A CG  1 
ATOM   3466  C CD  . PRO A 1 609 ? 97.541  108.742 114.628 1.00 165.63 ? 608 PRO A CD  1 
ATOM   3467  N N   . LEU A 1 610 ? 99.982  109.364 118.568 1.00 142.76 ? 609 LEU A N   1 
ATOM   3468  C CA  . LEU A 1 610 ? 100.094 110.169 119.776 1.00 134.11 ? 609 LEU A CA  1 
ATOM   3469  C C   . LEU A 1 610 ? 101.385 110.977 119.766 1.00 122.45 ? 609 LEU A C   1 
ATOM   3470  O O   . LEU A 1 610 ? 102.372 110.481 119.236 1.00 81.55  ? 609 LEU A O   1 
ATOM   3471  C CB  . LEU A 1 610 ? 100.128 109.210 120.959 1.00 133.49 ? 609 LEU A CB  1 
ATOM   3472  C CG  . LEU A 1 610 ? 98.825  108.515 121.299 1.00 155.23 ? 609 LEU A CG  1 
ATOM   3473  C CD1 . LEU A 1 610 ? 99.144  107.409 122.262 1.00 147.96 ? 609 LEU A CD1 1 
ATOM   3474  C CD2 . LEU A 1 610 ? 97.823  109.491 121.907 1.00 178.59 ? 609 LEU A CD2 1 
ATOM   3475  N N   . GLU A 1 611 ? 101.344 112.196 120.354 1.00 125.76 ? 610 GLU A N   1 
ATOM   3476  C CA  . GLU A 1 611 ? 102.526 113.026 120.558 1.00 143.35 ? 610 GLU A CA  1 
ATOM   3477  C C   . GLU A 1 611 ? 103.156 112.594 121.872 1.00 147.01 ? 610 GLU A C   1 
ATOM   3478  O O   . GLU A 1 611 ? 102.634 112.836 122.962 1.00 156.32 ? 610 GLU A O   1 
ATOM   3479  C CB  . GLU A 1 611 ? 102.223 114.528 120.631 1.00 233.26 ? 610 GLU A CB  1 
ATOM   3480  C CG  . GLU A 1 611 ? 101.665 115.112 119.348 1.00 321.45 ? 610 GLU A CG  1 
ATOM   3481  C CD  . GLU A 1 611 ? 100.213 114.794 119.010 1.00 416.73 ? 610 GLU A CD  1 
ATOM   3482  O OE1 . GLU A 1 611 ? 99.462  114.346 119.914 1.00 416.81 ? 610 GLU A OE1 1 
ATOM   3483  O OE2 . GLU A 1 611 ? 99.835  114.980 117.835 1.00 472.17 ? 610 GLU A OE2 1 
ATOM   3484  N N   . LEU A 1 612 ? 104.319 111.973 121.802 1.00 124.95 ? 611 LEU A N   1 
ATOM   3485  C CA  . LEU A 1 612 ? 104.924 111.422 122.991 1.00 96.75  ? 611 LEU A CA  1 
ATOM   3486  C C   . LEU A 1 612 ? 105.347 112.544 123.930 1.00 103.76 ? 611 LEU A C   1 
ATOM   3487  O O   . LEU A 1 612 ? 105.236 112.391 125.140 1.00 167.32 ? 611 LEU A O   1 
ATOM   3488  C CB  . LEU A 1 612 ? 106.124 110.589 122.519 1.00 122.49 ? 611 LEU A CB  1 
ATOM   3489  C CG  . LEU A 1 612 ? 105.744 109.306 121.740 1.00 104.70 ? 611 LEU A CG  1 
ATOM   3490  C CD1 . LEU A 1 612 ? 106.928 108.273 121.601 1.00 80.47  ? 611 LEU A CD1 1 
ATOM   3491  C CD2 . LEU A 1 612 ? 104.458 108.640 122.327 1.00 72.63  ? 611 LEU A CD2 1 
ATOM   3492  N N   . GLU A 1 613 ? 105.844 113.686 123.434 1.00 119.83 ? 612 GLU A N   1 
ATOM   3493  C CA  . GLU A 1 613 ? 106.224 114.779 124.335 1.00 107.97 ? 612 GLU A CA  1 
ATOM   3494  C C   . GLU A 1 613 ? 105.001 115.438 125.007 1.00 86.72  ? 612 GLU A C   1 
ATOM   3495  O O   . GLU A 1 613 ? 105.233 116.191 125.985 1.00 149.17 ? 612 GLU A O   1 
ATOM   3496  C CB  . GLU A 1 613 ? 107.143 115.744 123.591 1.00 161.41 ? 612 GLU A CB  1 
ATOM   3497  C CG  . GLU A 1 613 ? 107.799 116.827 124.443 1.00 233.76 ? 612 GLU A CG  1 
ATOM   3498  C CD  . GLU A 1 613 ? 108.603 117.849 123.651 1.00 359.67 ? 612 GLU A CD  1 
ATOM   3499  O OE1 . GLU A 1 613 ? 109.714 117.499 123.201 1.00 406.17 ? 612 GLU A OE1 1 
ATOM   3500  O OE2 . GLU A 1 613 ? 108.111 118.994 123.482 1.00 420.66 ? 612 GLU A OE2 1 
ATOM   3501  N N   . ARG A 1 614 ? 103.733 115.147 124.606 1.00 70.98  ? 613 ARG A N   1 
ATOM   3502  C CA  . ARG A 1 614 ? 102.539 115.776 125.224 1.00 117.79 ? 613 ARG A CA  1 
ATOM   3503  C C   . ARG A 1 614 ? 101.422 114.783 125.595 1.00 123.79 ? 613 ARG A C   1 
ATOM   3504  O O   . ARG A 1 614 ? 100.273 115.157 125.804 1.00 156.97 ? 613 ARG A O   1 
ATOM   3505  C CB  . ARG A 1 614 ? 102.005 116.881 124.309 1.00 173.98 ? 613 ARG A CB  1 
ATOM   3506  C CG  . ARG A 1 614 ? 102.641 118.242 124.585 1.00 205.74 ? 613 ARG A CG  1 
ATOM   3507  C CD  . ARG A 1 614 ? 102.516 119.349 123.549 1.00 177.29 ? 613 ARG A CD  1 
ATOM   3508  N NE  . ARG A 1 614 ? 103.362 119.080 122.378 1.00 273.04 ? 613 ARG A NE  1 
ATOM   3509  C CZ  . ARG A 1 614 ? 104.703 119.130 122.318 1.00 330.03 ? 613 ARG A CZ  1 
ATOM   3510  N NH1 . ARG A 1 614 ? 105.313 118.750 121.204 1.00 368.07 ? 613 ARG A NH1 1 
ATOM   3511  N NH2 . ARG A 1 614 ? 105.432 119.534 123.353 1.00 300.73 ? 613 ARG A NH2 1 
ATOM   3512  N N   . LEU A 1 615 ? 101.797 113.511 125.721 1.00 110.35 ? 614 LEU A N   1 
ATOM   3513  C CA  . LEU A 1 615 ? 100.983 112.376 126.134 1.00 110.95 ? 614 LEU A CA  1 
ATOM   3514  C C   . LEU A 1 615 ? 100.551 112.461 127.602 1.00 112.81 ? 614 LEU A C   1 
ATOM   3515  O O   . LEU A 1 615 ? 101.238 113.116 128.390 1.00 149.02 ? 614 LEU A O   1 
ATOM   3516  C CB  . LEU A 1 615 ? 101.904 111.176 125.897 1.00 106.38 ? 614 LEU A CB  1 
ATOM   3517  C CG  . LEU A 1 615 ? 101.350 109.801 126.175 1.00 134.03 ? 614 LEU A CG  1 
ATOM   3518  C CD1 . LEU A 1 615 ? 100.120 109.552 125.321 1.00 218.86 ? 614 LEU A CD1 1 
ATOM   3519  C CD2 . LEU A 1 615 ? 102.411 108.762 125.870 1.00 89.13  ? 614 LEU A CD2 1 
ATOM   3520  N N   . LYS A 1 616 ? 99.439  111.801 127.990 1.00 114.03 ? 615 LYS A N   1 
ATOM   3521  C CA  . LYS A 1 616 ? 98.973  111.871 129.381 1.00 138.12 ? 615 LYS A CA  1 
ATOM   3522  C C   . LYS A 1 616 ? 98.499  110.511 129.885 1.00 124.02 ? 615 LYS A C   1 
ATOM   3523  O O   . LYS A 1 616 ? 97.382  110.136 129.581 1.00 199.12 ? 615 LYS A O   1 
ATOM   3524  C CB  . LYS A 1 616 ? 97.840  112.905 129.566 1.00 133.47 ? 615 LYS A CB  1 
ATOM   3525  C CG  . LYS A 1 616 ? 98.203  114.366 129.268 1.00 152.77 ? 615 LYS A CG  1 
ATOM   3526  C CD  . LYS A 1 616 ? 97.462  115.441 130.088 1.00 225.56 ? 615 LYS A CD  1 
ATOM   3527  C CE  . LYS A 1 616 ? 95.953  115.301 130.164 1.00 277.67 ? 615 LYS A CE  1 
ATOM   3528  N NZ  . LYS A 1 616 ? 95.384  116.204 131.197 1.00 286.58 ? 615 LYS A NZ  1 
ATOM   3529  N N   . LEU A 1 617 ? 99.326  109.781 130.655 1.00 91.05  ? 616 LEU A N   1 
ATOM   3530  C CA  . LEU A 1 617 ? 98.959  108.522 131.298 1.00 76.67  ? 616 LEU A CA  1 
ATOM   3531  C C   . LEU A 1 617 ? 98.084  108.775 132.537 1.00 85.83  ? 616 LEU A C   1 
ATOM   3532  O O   . LEU A 1 617 ? 98.349  109.676 133.344 1.00 72.92  ? 616 LEU A O   1 
ATOM   3533  C CB  . LEU A 1 617 ? 100.192 107.784 131.789 1.00 61.70  ? 616 LEU A CB  1 
ATOM   3534  C CG  . LEU A 1 617 ? 101.217 107.229 130.801 1.00 84.87  ? 616 LEU A CG  1 
ATOM   3535  C CD1 . LEU A 1 617 ? 100.599 106.250 129.825 1.00 92.98  ? 616 LEU A CD1 1 
ATOM   3536  C CD2 . LEU A 1 617 ? 102.012 108.368 130.088 1.00 108.86 ? 616 LEU A CD2 1 
ATOM   3537  N N   . GLU A 1 618 ? 97.024  107.964 132.703 1.00 66.15  ? 617 GLU A N   1 
ATOM   3538  C CA  . GLU A 1 618 ? 96.256  107.990 133.934 1.00 76.29  ? 617 GLU A CA  1 
ATOM   3539  C C   . GLU A 1 618 ? 96.935  107.083 134.931 1.00 73.13  ? 617 GLU A C   1 
ATOM   3540  O O   . GLU A 1 618 ? 97.791  106.321 134.518 1.00 93.75  ? 617 GLU A O   1 
ATOM   3541  C CB  . GLU A 1 618 ? 94.821  107.575 133.685 1.00 128.92 ? 617 GLU A CB  1 
ATOM   3542  C CG  . GLU A 1 618 ? 94.026  108.618 132.898 1.00 205.74 ? 617 GLU A CG  1 
ATOM   3543  C CD  . GLU A 1 618 ? 93.902  109.999 133.544 1.00 262.62 ? 617 GLU A CD  1 
ATOM   3544  O OE1 . GLU A 1 618 ? 93.505  110.056 134.731 1.00 264.55 ? 617 GLU A OE1 1 
ATOM   3545  O OE2 . GLU A 1 618 ? 94.191  111.027 132.862 1.00 318.49 ? 617 GLU A OE2 1 
ATOM   3546  N N   . PRO A 1 619 ? 96.629  107.113 136.250 1.00 67.51  ? 618 PRO A N   1 
ATOM   3547  C CA  . PRO A 1 619 ? 97.116  106.098 137.180 1.00 67.16  ? 618 PRO A CA  1 
ATOM   3548  C C   . PRO A 1 619 ? 96.822  104.682 136.679 1.00 90.88  ? 618 PRO A C   1 
ATOM   3549  O O   . PRO A 1 619 ? 95.683  104.319 136.343 1.00 105.55 ? 618 PRO A O   1 
ATOM   3550  C CB  . PRO A 1 619 ? 96.372  106.361 138.457 1.00 80.74  ? 618 PRO A CB  1 
ATOM   3551  C CG  . PRO A 1 619 ? 96.034  107.793 138.390 1.00 107.74 ? 618 PRO A CG  1 
ATOM   3552  C CD  . PRO A 1 619 ? 95.840  108.127 136.918 1.00 93.99  ? 618 PRO A CD  1 
ATOM   3553  N N   . HIS A 1 620 ? 97.894  103.885 136.599 1.00 75.36  ? 619 HIS A N   1 
ATOM   3554  C CA  . HIS A 1 620 ? 97.829  102.508 136.169 1.00 73.23  ? 619 HIS A CA  1 
ATOM   3555  C C   . HIS A 1 620 ? 97.483  102.334 134.679 1.00 74.34  ? 619 HIS A C   1 
ATOM   3556  O O   . HIS A 1 620 ? 97.198  101.224 134.219 1.00 89.26  ? 619 HIS A O   1 
ATOM   3557  C CB  . HIS A 1 620 ? 96.921  101.778 137.172 1.00 96.34  ? 619 HIS A CB  1 
ATOM   3558  C CG  . HIS A 1 620 ? 97.308  101.938 138.609 1.00 82.31  ? 619 HIS A CG  1 
ATOM   3559  N ND1 . HIS A 1 620 ? 96.431  102.436 139.553 1.00 108.79 ? 619 HIS A ND1 1 
ATOM   3560  C CD2 . HIS A 1 620 ? 98.461  101.607 139.253 1.00 71.61  ? 619 HIS A CD2 1 
ATOM   3561  C CE1 . HIS A 1 620 ? 97.071  102.434 140.724 1.00 193.44 ? 619 HIS A CE1 1 
ATOM   3562  N NE2 . HIS A 1 620 ? 98.309  101.937 140.560 1.00 120.89 ? 619 HIS A NE2 1 
ATOM   3563  N N   . GLU A 1 621 ? 97.510  103.397 133.890 1.00 75.84  ? 620 GLU A N   1 
ATOM   3564  C CA  . GLU A 1 621 ? 97.290  103.212 132.466 1.00 98.36  ? 620 GLU A CA  1 
ATOM   3565  C C   . GLU A 1 621 ? 98.555  102.668 131.827 1.00 65.78  ? 620 GLU A C   1 
ATOM   3566  O O   . GLU A 1 621 ? 99.516  103.380 131.715 1.00 82.40  ? 620 GLU A O   1 
ATOM   3567  C CB  . GLU A 1 621 ? 96.916  104.523 131.756 1.00 129.61 ? 620 GLU A CB  1 
ATOM   3568  C CG  . GLU A 1 621 ? 96.833  104.444 130.225 1.00 126.33 ? 620 GLU A CG  1 
ATOM   3569  C CD  . GLU A 1 621 ? 95.899  105.481 129.610 1.00 207.96 ? 620 GLU A CD  1 
ATOM   3570  O OE1 . GLU A 1 621 ? 95.788  106.594 130.157 1.00 229.41 ? 620 GLU A OE1 1 
ATOM   3571  O OE2 . GLU A 1 621 ? 95.283  105.205 128.561 1.00 297.20 ? 620 GLU A OE2 1 
ATOM   3572  N N   . GLY A 1 622 ? 98.527  101.444 131.350 1.00 59.84  ? 621 GLY A N   1 
ATOM   3573  C CA  . GLY A 1 622 ? 99.509  101.006 130.360 1.00 78.31  ? 621 GLY A CA  1 
ATOM   3574  C C   . GLY A 1 622 ? 99.164  101.191 128.880 1.00 57.50  ? 621 GLY A C   1 
ATOM   3575  O O   . GLY A 1 622 ? 98.072  101.012 128.502 1.00 66.91  ? 621 GLY A O   1 
ATOM   3576  N N   . LEU A 1 623 ? 100.139 101.525 128.047 1.00 62.97  ? 622 LEU A N   1 
ATOM   3577  C CA  . LEU A 1 623 ? 99.977  101.742 126.618 1.00 76.75  ? 622 LEU A CA  1 
ATOM   3578  C C   . LEU A 1 623 ? 100.878 100.827 125.842 1.00 80.65  ? 622 LEU A C   1 
ATOM   3579  O O   . LEU A 1 623 ? 102.002 100.627 126.270 1.00 121.75 ? 622 LEU A O   1 
ATOM   3580  C CB  . LEU A 1 623 ? 100.491 103.115 126.187 1.00 66.56  ? 622 LEU A CB  1 
ATOM   3581  C CG  . LEU A 1 623 ? 99.835  104.255 126.906 1.00 74.48  ? 622 LEU A CG  1 
ATOM   3582  C CD1 . LEU A 1 623 ? 100.497 105.528 126.408 1.00 87.56  ? 622 LEU A CD1 1 
ATOM   3583  C CD2 . LEU A 1 623 ? 98.330  104.196 126.706 1.00 62.97  ? 622 LEU A CD2 1 
ATOM   3584  N N   . LEU A 1 624 ? 100.391 100.350 124.703 1.00 63.91  ? 623 LEU A N   1 
ATOM   3585  C CA  . LEU A 1 624 ? 101.234 99.690  123.735 1.00 64.16  ? 623 LEU A CA  1 
ATOM   3586  C C   . LEU A 1 624 ? 101.274 100.544 122.474 1.00 64.85  ? 623 LEU A C   1 
ATOM   3587  O O   . LEU A 1 624 ? 100.317 100.644 121.778 1.00 99.81  ? 623 LEU A O   1 
ATOM   3588  C CB  . LEU A 1 624 ? 100.653 98.298  123.509 1.00 61.17  ? 623 LEU A CB  1 
ATOM   3589  C CG  . LEU A 1 624 ? 101.416 97.407  122.544 1.00 72.99  ? 623 LEU A CG  1 
ATOM   3590  C CD1 . LEU A 1 624 ? 102.890 97.297  122.832 1.00 95.15  ? 623 LEU A CD1 1 
ATOM   3591  C CD2 . LEU A 1 624 ? 100.810 96.003  122.633 1.00 73.81  ? 623 LEU A CD2 1 
ATOM   3592  N N   . LEU A 1 625 ? 102.394 101.162 122.184 1.00 107.47 ? 624 LEU A N   1 
ATOM   3593  C CA  . LEU A 1 625 ? 102.541 101.991 120.998 1.00 81.77  ? 624 LEU A CA  1 
ATOM   3594  C C   . LEU A 1 625 ? 103.378 101.167 120.044 1.00 96.14  ? 624 LEU A C   1 
ATOM   3595  O O   . LEU A 1 625 ? 104.301 100.434 120.434 1.00 141.79 ? 624 LEU A O   1 
ATOM   3596  C CB  . LEU A 1 625 ? 103.246 103.332 121.358 1.00 83.98  ? 624 LEU A CB  1 
ATOM   3597  C CG  . LEU A 1 625 ? 102.633 104.046 122.569 1.00 89.85  ? 624 LEU A CG  1 
ATOM   3598  C CD1 . LEU A 1 625 ? 103.171 105.430 122.740 1.00 118.80 ? 624 LEU A CD1 1 
ATOM   3599  C CD2 . LEU A 1 625 ? 101.157 104.198 122.401 1.00 86.04  ? 624 LEU A CD2 1 
ATOM   3600  N N   . ARG A 1 626 ? 103.041 101.348 118.781 1.00 98.03  ? 625 ARG A N   1 
ATOM   3601  C CA  . ARG A 1 626 ? 103.680 100.705 117.649 1.00 101.59 ? 625 ARG A CA  1 
ATOM   3602  C C   . ARG A 1 626 ? 104.291 101.843 116.823 1.00 89.36  ? 625 ARG A C   1 
ATOM   3603  O O   . ARG A 1 626 ? 103.683 102.899 116.631 1.00 109.31 ? 625 ARG A O   1 
ATOM   3604  C CB  . ARG A 1 626 ? 102.544 99.889  117.025 1.00 150.43 ? 625 ARG A CB  1 
ATOM   3605  C CG  . ARG A 1 626 ? 102.760 99.353  115.637 1.00 142.45 ? 625 ARG A CG  1 
ATOM   3606  C CD  . ARG A 1 626 ? 101.457 98.855  114.997 1.00 157.28 ? 625 ARG A CD  1 
ATOM   3607  N NE  . ARG A 1 626 ? 101.830 98.095  113.807 1.00 218.87 ? 625 ARG A NE  1 
ATOM   3608  C CZ  . ARG A 1 626 ? 101.886 96.759  113.700 1.00 250.65 ? 625 ARG A CZ  1 
ATOM   3609  N NH1 . ARG A 1 626 ? 102.599 96.202  112.732 1.00 335.54 ? 625 ARG A NH1 1 
ATOM   3610  N NH2 . ARG A 1 626 ? 101.266 95.962  114.563 1.00 158.19 ? 625 ARG A NH2 1 
ATOM   3611  N N   . PHE A 1 627 ? 105.500 101.661 116.310 1.00 105.52 ? 626 PHE A N   1 
ATOM   3612  C CA  . PHE A 1 627 ? 106.058 102.675 115.430 1.00 138.03 ? 626 PHE A CA  1 
ATOM   3613  C C   . PHE A 1 627 ? 107.021 102.069 114.407 1.00 138.88 ? 626 PHE A C   1 
ATOM   3614  O O   . PHE A 1 627 ? 107.692 101.070 114.684 1.00 164.81 ? 626 PHE A O   1 
ATOM   3615  C CB  . PHE A 1 627 ? 106.736 103.788 116.238 1.00 132.55 ? 626 PHE A CB  1 
ATOM   3616  C CG  . PHE A 1 627 ? 107.890 103.436 117.151 1.00 110.26 ? 626 PHE A CG  1 
ATOM   3617  C CD1 . PHE A 1 627 ? 109.180 103.177 116.692 1.00 132.28 ? 626 PHE A CD1 1 
ATOM   3618  C CD2 . PHE A 1 627 ? 107.683 103.411 118.501 1.00 147.32 ? 626 PHE A CD2 1 
ATOM   3619  C CE1 . PHE A 1 627 ? 110.211 102.863 117.548 1.00 116.10 ? 626 PHE A CE1 1 
ATOM   3620  C CE2 . PHE A 1 627 ? 108.729 103.095 119.348 1.00 159.71 ? 626 PHE A CE2 1 
ATOM   3621  C CZ  . PHE A 1 627 ? 109.972 102.823 118.877 1.00 117.28 ? 626 PHE A CZ  1 
ATOM   3622  N N   . PRO A 1 628 ? 107.125 102.677 113.198 1.00 124.68 ? 627 PRO A N   1 
ATOM   3623  C CA  . PRO A 1 628 ? 107.964 102.127 112.149 1.00 114.56 ? 627 PRO A CA  1 
ATOM   3624  C C   . PRO A 1 628 ? 109.441 102.463 112.264 1.00 114.00 ? 627 PRO A C   1 
ATOM   3625  O O   . PRO A 1 628 ? 109.825 103.403 112.982 1.00 147.38 ? 627 PRO A O   1 
ATOM   3626  C CB  . PRO A 1 628 ? 107.391 102.859 110.936 1.00 216.44 ? 627 PRO A CB  1 
ATOM   3627  C CG  . PRO A 1 628 ? 107.092 104.276 111.467 1.00 184.89 ? 627 PRO A CG  1 
ATOM   3628  C CD  . PRO A 1 628 ? 106.462 103.939 112.792 1.00 183.35 ? 627 PRO A CD  1 
ATOM   3629  N N   . TYR A 1 629 ? 110.247 101.666 111.538 1.00 108.15 ? 628 TYR A N   1 
ATOM   3630  C CA  . TYR A 1 629 ? 111.706 101.759 111.581 1.00 138.27 ? 628 TYR A CA  1 
ATOM   3631  C C   . TYR A 1 629 ? 112.262 103.073 111.010 1.00 135.76 ? 628 TYR A C   1 
ATOM   3632  O O   . TYR A 1 629 ? 111.545 103.839 110.370 1.00 138.44 ? 628 TYR A O   1 
ATOM   3633  C CB  . TYR A 1 629 ? 112.244 100.545 110.820 1.00 164.80 ? 628 TYR A CB  1 
ATOM   3634  C CG  . TYR A 1 629 ? 113.760 100.382 110.773 1.00 143.35 ? 628 TYR A CG  1 
ATOM   3635  C CD1 . TYR A 1 629 ? 114.498 100.107 111.913 1.00 172.79 ? 628 TYR A CD1 1 
ATOM   3636  C CD2 . TYR A 1 629 ? 114.456 100.485 109.577 1.00 155.83 ? 628 TYR A CD2 1 
ATOM   3637  C CE1 . TYR A 1 629 ? 115.874 99.946  111.860 1.00 223.27 ? 628 TYR A CE1 1 
ATOM   3638  C CE2 . TYR A 1 629 ? 115.834 100.324 109.511 1.00 156.43 ? 628 TYR A CE2 1 
ATOM   3639  C CZ  . TYR A 1 629 ? 116.554 100.059 110.657 1.00 167.23 ? 628 TYR A CZ  1 
ATOM   3640  O OH  . TYR A 1 629 ? 117.912 99.889  110.601 1.00 152.55 ? 628 TYR A OH  1 
ATOM   3641  N N   . ALA A 1 630 ? 113.549 103.323 111.278 1.00 128.77 ? 629 ALA A N   1 
ATOM   3642  C CA  . ALA A 1 630 ? 114.314 104.370 110.615 1.00 182.91 ? 629 ALA A CA  1 
ATOM   3643  C C   . ALA A 1 630 ? 115.734 103.861 110.337 1.00 213.72 ? 629 ALA A C   1 
ATOM   3644  O O   . ALA A 1 630 ? 116.427 103.327 111.219 1.00 150.21 ? 629 ALA A O   1 
ATOM   3645  C CB  . ALA A 1 630 ? 114.336 105.623 111.462 1.00 243.20 ? 629 ALA A CB  1 
ATOM   3646  N N   . ALA A 1 631 ? 116.180 104.043 109.080 1.00 322.09 ? 630 ALA A N   1 
ATOM   3647  C CA  . ALA A 1 631 ? 117.495 103.611 108.625 1.00 435.83 ? 630 ALA A CA  1 
ATOM   3648  C C   . ALA A 1 631 ? 118.573 104.591 109.120 1.00 513.62 ? 630 ALA A C   1 
ATOM   3649  O O   . ALA A 1 631 ? 118.941 105.516 108.358 1.00 575.03 ? 630 ALA A O   1 
ATOM   3650  C CB  . ALA A 1 631 ? 117.494 103.475 107.117 1.00 470.67 ? 630 ALA A CB  1 
ATOM   3651  N N   . THR B 2 51  ? 90.252  76.493  65.608  1.00 270.04 ? 51  THR B N   1 
ATOM   3652  C CA  . THR B 2 51  ? 89.152  75.901  66.435  1.00 371.64 ? 51  THR B CA  1 
ATOM   3653  C C   . THR B 2 51  ? 89.021  76.658  67.757  1.00 354.75 ? 51  THR B C   1 
ATOM   3654  O O   . THR B 2 51  ? 90.007  77.238  68.198  1.00 364.60 ? 51  THR B O   1 
ATOM   3655  C CB  . THR B 2 51  ? 89.359  74.400  66.716  1.00 400.28 ? 51  THR B CB  1 
ATOM   3656  O OG1 . THR B 2 51  ? 90.597  74.211  67.405  1.00 391.58 ? 51  THR B OG1 1 
ATOM   3657  C CG2 . THR B 2 51  ? 89.358  73.537  65.471  1.00 412.05 ? 51  THR B CG2 1 
ATOM   3658  N N   . LEU B 2 52  ? 87.825  76.632  68.380  1.00 331.34 ? 52  LEU B N   1 
ATOM   3659  C CA  . LEU B 2 52  ? 87.512  77.418  69.577  1.00 313.15 ? 52  LEU B CA  1 
ATOM   3660  C C   . LEU B 2 52  ? 88.459  77.074  70.737  1.00 310.49 ? 52  LEU B C   1 
ATOM   3661  O O   . LEU B 2 52  ? 88.904  77.984  71.440  1.00 385.18 ? 52  LEU B O   1 
ATOM   3662  C CB  . LEU B 2 52  ? 86.037  77.214  69.962  1.00 323.14 ? 52  LEU B CB  1 
ATOM   3663  C CG  . LEU B 2 52  ? 85.551  77.875  71.261  1.00 310.70 ? 52  LEU B CG  1 
ATOM   3664  C CD1 . LEU B 2 52  ? 85.606  79.397  71.187  1.00 323.92 ? 52  LEU B CD1 1 
ATOM   3665  C CD2 . LEU B 2 52  ? 84.136  77.436  71.609  1.00 307.06 ? 52  LEU B CD2 1 
ATOM   3666  N N   . LEU B 2 53  ? 88.778  75.779  70.927  1.00 302.70 ? 53  LEU B N   1 
ATOM   3667  C CA  . LEU B 2 53  ? 89.671  75.308  71.989  1.00 350.11 ? 53  LEU B CA  1 
ATOM   3668  C C   . LEU B 2 53  ? 91.071  75.943  71.896  1.00 341.64 ? 53  LEU B C   1 
ATOM   3669  O O   . LEU B 2 53  ? 91.669  76.249  72.936  1.00 397.09 ? 53  LEU B O   1 
ATOM   3670  C CB  . LEU B 2 53  ? 89.733  73.773  71.926  1.00 403.74 ? 53  LEU B CB  1 
ATOM   3671  C CG  . LEU B 2 53  ? 90.571  73.058  72.991  1.00 402.13 ? 53  LEU B CG  1 
ATOM   3672  C CD1 . LEU B 2 53  ? 89.974  73.230  74.384  1.00 403.14 ? 53  LEU B CD1 1 
ATOM   3673  C CD2 . LEU B 2 53  ? 90.718  71.577  72.651  1.00 341.89 ? 53  LEU B CD2 1 
ATOM   3674  N N   . ASN B 2 54  ? 91.590  76.145  70.671  1.00 293.55 ? 54  ASN B N   1 
ATOM   3675  C CA  . ASN B 2 54  ? 92.876  76.804  70.451  1.00 311.58 ? 54  ASN B CA  1 
ATOM   3676  C C   . ASN B 2 54  ? 92.763  78.335  70.548  1.00 339.55 ? 54  ASN B C   1 
ATOM   3677  O O   . ASN B 2 54  ? 93.758  78.994  70.853  1.00 393.73 ? 54  ASN B O   1 
ATOM   3678  C CB  . ASN B 2 54  ? 93.501  76.372  69.121  1.00 321.43 ? 54  ASN B CB  1 
ATOM   3679  C CG  . ASN B 2 54  ? 94.983  76.706  69.051  1.00 283.45 ? 54  ASN B CG  1 
ATOM   3680  O OD1 . ASN B 2 54  ? 95.757  76.304  69.922  1.00 199.95 ? 54  ASN B OD1 1 
ATOM   3681  N ND2 . ASN B 2 54  ? 95.383  77.450  68.030  1.00 270.19 ? 54  ASN B ND2 1 
ATOM   3682  N N   . GLY B 2 55  ? 91.566  78.912  70.303  1.00 312.60 ? 55  GLY B N   1 
ATOM   3683  C CA  . GLY B 2 55  ? 91.272  80.316  70.592  1.00 262.58 ? 55  GLY B CA  1 
ATOM   3684  C C   . GLY B 2 55  ? 91.422  80.657  72.075  1.00 287.84 ? 55  GLY B C   1 
ATOM   3685  O O   . GLY B 2 55  ? 92.111  81.606  72.411  1.00 285.32 ? 55  GLY B O   1 
ATOM   3686  N N   . VAL B 2 56  ? 90.798  79.866  72.959  1.00 310.67 ? 56  VAL B N   1 
ATOM   3687  C CA  . VAL B 2 56  ? 90.919  80.019  74.410  1.00 264.19 ? 56  VAL B CA  1 
ATOM   3688  C C   . VAL B 2 56  ? 92.393  79.973  74.846  1.00 214.74 ? 56  VAL B C   1 
ATOM   3689  O O   . VAL B 2 56  ? 92.788  80.752  75.696  1.00 302.85 ? 56  VAL B O   1 
ATOM   3690  C CB  . VAL B 2 56  ? 90.045  78.980  75.150  1.00 273.90 ? 56  VAL B CB  1 
ATOM   3691  C CG1 . VAL B 2 56  ? 90.296  78.891  76.655  1.00 272.27 ? 56  VAL B CG1 1 
ATOM   3692  C CG2 . VAL B 2 56  ? 88.573  79.248  74.883  1.00 253.97 ? 56  VAL B CG2 1 
ATOM   3693  N N   . ALA B 2 57  ? 93.222  79.094  74.277  1.00 202.94 ? 57  ALA B N   1 
ATOM   3694  C CA  . ALA B 2 57  ? 94.647  79.046  74.603  1.00 254.93 ? 57  ALA B CA  1 
ATOM   3695  C C   . ALA B 2 57  ? 95.432  80.306  74.164  1.00 255.36 ? 57  ALA B C   1 
ATOM   3696  O O   . ALA B 2 57  ? 96.554  80.505  74.634  1.00 206.71 ? 57  ALA B O   1 
ATOM   3697  C CB  . ALA B 2 57  ? 95.222  77.777  74.011  1.00 313.50 ? 57  ALA B CB  1 
ATOM   3698  N N   . ILE B 2 58  ? 94.879  81.147  73.263  1.00 250.26 ? 58  ILE B N   1 
ATOM   3699  C CA  . ILE B 2 58  ? 95.459  82.439  72.896  1.00 269.05 ? 58  ILE B CA  1 
ATOM   3700  C C   . ILE B 2 58  ? 94.986  83.509  73.880  1.00 217.44 ? 58  ILE B C   1 
ATOM   3701  O O   . ILE B 2 58  ? 95.821  84.277  74.362  1.00 308.01 ? 58  ILE B O   1 
ATOM   3702  C CB  . ILE B 2 58  ? 95.143  82.808  71.421  1.00 345.13 ? 58  ILE B CB  1 
ATOM   3703  C CG1 . ILE B 2 58  ? 95.877  81.885  70.431  1.00 349.08 ? 58  ILE B CG1 1 
ATOM   3704  C CG2 . ILE B 2 58  ? 95.393  84.283  71.099  1.00 371.91 ? 58  ILE B CG2 1 
ATOM   3705  C CD1 . ILE B 2 58  ? 97.406  81.965  70.443  1.00 306.39 ? 58  ILE B CD1 1 
ATOM   3706  N N   . ILE B 2 59  ? 93.673  83.573  74.175  1.00 151.86 ? 59  ILE B N   1 
ATOM   3707  C CA  . ILE B 2 59  ? 93.159  84.623  75.066  1.00 220.52 ? 59  ILE B CA  1 
ATOM   3708  C C   . ILE B 2 59  ? 93.628  84.405  76.532  1.00 245.17 ? 59  ILE B C   1 
ATOM   3709  O O   . ILE B 2 59  ? 94.096  85.351  77.156  1.00 287.64 ? 59  ILE B O   1 
ATOM   3710  C CB  . ILE B 2 59  ? 91.633  84.887  74.900  1.00 214.17 ? 59  ILE B CB  1 
ATOM   3711  C CG1 . ILE B 2 59  ? 91.123  85.906  75.930  1.00 257.00 ? 59  ILE B CG1 1 
ATOM   3712  C CG2 . ILE B 2 59  ? 90.799  83.615  74.922  1.00 233.75 ? 59  ILE B CG2 1 
ATOM   3713  C CD1 . ILE B 2 59  ? 89.742  86.445  75.644  1.00 231.17 ? 59  ILE B CD1 1 
ATOM   3714  N N   . VAL B 2 60  ? 93.567  83.198  77.108  1.00 210.01 ? 60  VAL B N   1 
ATOM   3715  C CA  . VAL B 2 60  ? 93.992  82.994  78.495  1.00 188.48 ? 60  VAL B CA  1 
ATOM   3716  C C   . VAL B 2 60  ? 95.470  83.386  78.684  1.00 217.22 ? 60  VAL B C   1 
ATOM   3717  O O   . VAL B 2 60  ? 95.809  84.028  79.663  1.00 283.20 ? 60  VAL B O   1 
ATOM   3718  C CB  . VAL B 2 60  ? 93.710  81.547  78.975  1.00 259.48 ? 60  VAL B CB  1 
ATOM   3719  C CG1 . VAL B 2 60  ? 94.712  80.489  78.499  1.00 307.21 ? 60  VAL B CG1 1 
ATOM   3720  C CG2 . VAL B 2 60  ? 93.621  81.468  80.482  1.00 281.26 ? 60  VAL B CG2 1 
ATOM   3721  N N   . GLY B 2 61  ? 96.367  83.014  77.763  1.00 230.80 ? 61  GLY B N   1 
ATOM   3722  C CA  . GLY B 2 61  ? 97.777  83.394  77.789  1.00 236.96 ? 61  GLY B CA  1 
ATOM   3723  C C   . GLY B 2 61  ? 98.048  84.888  77.552  1.00 203.55 ? 61  GLY B C   1 
ATOM   3724  O O   . GLY B 2 61  ? 99.126  85.376  77.893  1.00 213.47 ? 61  GLY B O   1 
ATOM   3725  N N   . THR B 2 62  ? 97.077  85.603  76.966  1.00 185.60 ? 62  THR B N   1 
ATOM   3726  C CA  . THR B 2 62  ? 97.107  87.053  76.807  1.00 201.75 ? 62  THR B CA  1 
ATOM   3727  C C   . THR B 2 62  ? 96.658  87.773  78.087  1.00 239.61 ? 62  THR B C   1 
ATOM   3728  O O   . THR B 2 62  ? 97.279  88.765  78.462  1.00 303.22 ? 62  THR B O   1 
ATOM   3729  C CB  . THR B 2 62  ? 96.233  87.484  75.617  1.00 266.36 ? 62  THR B CB  1 
ATOM   3730  O OG1 . THR B 2 62  ? 96.761  86.850  74.443  1.00 325.61 ? 62  THR B OG1 1 
ATOM   3731  C CG2 . THR B 2 62  ? 96.135  88.988  75.433  1.00 241.74 ? 62  THR B CG2 1 
ATOM   3732  N N   . ILE B 2 63  ? 95.592  87.287  78.752  1.00 223.01 ? 63  ILE B N   1 
ATOM   3733  C CA  . ILE B 2 63  ? 94.986  87.953  79.905  1.00 235.33 ? 63  ILE B CA  1 
ATOM   3734  C C   . ILE B 2 63  ? 95.824  87.792  81.186  1.00 242.23 ? 63  ILE B C   1 
ATOM   3735  O O   . ILE B 2 63  ? 95.902  88.751  81.957  1.00 223.27 ? 63  ILE B O   1 
ATOM   3736  C CB  . ILE B 2 63  ? 93.536  87.459  80.104  1.00 219.16 ? 63  ILE B CB  1 
ATOM   3737  C CG1 . ILE B 2 63  ? 92.621  87.818  78.925  1.00 271.09 ? 63  ILE B CG1 1 
ATOM   3738  C CG2 . ILE B 2 63  ? 92.967  87.956  81.418  1.00 235.10 ? 63  ILE B CG2 1 
ATOM   3739  C CD1 . ILE B 2 63  ? 92.464  89.304  78.632  1.00 278.25 ? 63  ILE B CD1 1 
ATOM   3740  N N   . ILE B 2 64  ? 96.446  86.617  81.415  1.00 226.94 ? 64  ILE B N   1 
ATOM   3741  C CA  . ILE B 2 64  ? 97.003  86.247  82.719  1.00 212.72 ? 64  ILE B CA  1 
ATOM   3742  C C   . ILE B 2 64  ? 98.070  87.233  83.220  1.00 243.89 ? 64  ILE B C   1 
ATOM   3743  O O   . ILE B 2 64  ? 98.161  87.442  84.426  1.00 291.37 ? 64  ILE B O   1 
ATOM   3744  C CB  . ILE B 2 64  ? 97.467  84.768  82.707  1.00 197.58 ? 64  ILE B CB  1 
ATOM   3745  C CG1 . ILE B 2 64  ? 96.264  83.893  83.064  1.00 277.14 ? 64  ILE B CG1 1 
ATOM   3746  C CG2 . ILE B 2 64  ? 98.636  84.470  83.633  1.00 216.91 ? 64  ILE B CG2 1 
ATOM   3747  C CD1 . ILE B 2 64  ? 96.487  82.402  82.950  1.00 348.89 ? 64  ILE B CD1 1 
ATOM   3748  N N   . GLY B 2 65  ? 98.876  87.838  82.347  1.00 266.57 ? 65  GLY B N   1 
ATOM   3749  C CA  . GLY B 2 65  ? 99.702  88.974  82.744  1.00 287.83 ? 65  GLY B CA  1 
ATOM   3750  C C   . GLY B 2 65  ? 100.795 88.663  83.778  1.00 277.40 ? 65  GLY B C   1 
ATOM   3751  O O   . GLY B 2 65  ? 101.156 87.508  84.019  1.00 245.23 ? 65  GLY B O   1 
ATOM   3752  N N   . SER B 2 66  ? 101.340 89.737  84.380  1.00 231.87 ? 66  SER B N   1 
ATOM   3753  C CA  . SER B 2 66  ? 102.268 89.645  85.506  1.00 201.55 ? 66  SER B CA  1 
ATOM   3754  C C   . SER B 2 66  ? 101.681 90.256  86.773  1.00 171.09 ? 66  SER B C   1 
ATOM   3755  O O   . SER B 2 66  ? 102.286 90.085  87.831  1.00 185.16 ? 66  SER B O   1 
ATOM   3756  C CB  . SER B 2 66  ? 103.609 90.291  85.196  1.00 193.63 ? 66  SER B CB  1 
ATOM   3757  O OG  . SER B 2 66  ? 104.290 89.597  84.173  1.00 159.36 ? 66  SER B OG  1 
ATOM   3758  N N   . GLY B 2 67  ? 100.540 90.953  86.691  1.00 172.26 ? 67  GLY B N   1 
ATOM   3759  C CA  . GLY B 2 67  ? 99.977  91.601  87.865  1.00 205.30 ? 67  GLY B CA  1 
ATOM   3760  C C   . GLY B 2 67  ? 99.657  90.634  89.013  1.00 194.28 ? 67  GLY B C   1 
ATOM   3761  O O   . GLY B 2 67  ? 99.594  91.049  90.162  1.00 182.91 ? 67  GLY B O   1 
ATOM   3762  N N   . ILE B 2 68  ? 99.437  89.348  88.716  1.00 175.85 ? 68  ILE B N   1 
ATOM   3763  C CA  . ILE B 2 68  ? 99.151  88.340  89.732  1.00 194.23 ? 68  ILE B CA  1 
ATOM   3764  C C   . ILE B 2 68  ? 100.300 88.175  90.744  1.00 183.11 ? 68  ILE B C   1 
ATOM   3765  O O   . ILE B 2 68  ? 100.097 87.619  91.823  1.00 191.34 ? 68  ILE B O   1 
ATOM   3766  C CB  . ILE B 2 68  ? 98.774  87.017  89.017  1.00 193.06 ? 68  ILE B CB  1 
ATOM   3767  C CG1 . ILE B 2 68  ? 98.194  85.962  89.961  1.00 192.75 ? 68  ILE B CG1 1 
ATOM   3768  C CG2 . ILE B 2 68  ? 99.943  86.429  88.240  1.00 159.39 ? 68  ILE B CG2 1 
ATOM   3769  C CD1 . ILE B 2 68  ? 97.025  86.433  90.801  1.00 185.40 ? 68  ILE B CD1 1 
ATOM   3770  N N   . PHE B 2 69  ? 101.512 88.640  90.426  1.00 148.66 ? 69  PHE B N   1 
ATOM   3771  C CA  . PHE B 2 69  ? 102.640 88.519  91.337  1.00 161.01 ? 69  PHE B CA  1 
ATOM   3772  C C   . PHE B 2 69  ? 102.801 89.742  92.237  1.00 166.72 ? 69  PHE B C   1 
ATOM   3773  O O   . PHE B 2 69  ? 103.524 89.653  93.236  1.00 175.23 ? 69  PHE B O   1 
ATOM   3774  C CB  . PHE B 2 69  ? 103.905 88.275  90.518  1.00 164.63 ? 69  PHE B CB  1 
ATOM   3775  C CG  . PHE B 2 69  ? 103.807 87.028  89.688  1.00 167.57 ? 69  PHE B CG  1 
ATOM   3776  C CD1 . PHE B 2 69  ? 103.603 85.805  90.292  1.00 153.69 ? 69  PHE B CD1 1 
ATOM   3777  C CD2 . PHE B 2 69  ? 103.885 87.081  88.306  1.00 199.35 ? 69  PHE B CD2 1 
ATOM   3778  C CE1 . PHE B 2 69  ? 103.498 84.659  89.525  1.00 168.22 ? 69  PHE B CE1 1 
ATOM   3779  C CE2 . PHE B 2 69  ? 103.785 85.929  87.544  1.00 199.47 ? 69  PHE B CE2 1 
ATOM   3780  C CZ  . PHE B 2 69  ? 103.594 84.720  88.159  1.00 164.88 ? 69  PHE B CZ  1 
ATOM   3781  N N   . VAL B 2 70  ? 102.143 90.863  91.872  1.00 154.90 ? 70  VAL B N   1 
ATOM   3782  C CA  . VAL B 2 70  ? 102.071 92.072  92.681  1.00 151.18 ? 70  VAL B CA  1 
ATOM   3783  C C   . VAL B 2 70  ? 100.887 92.007  93.636  1.00 192.61 ? 70  VAL B C   1 
ATOM   3784  O O   . VAL B 2 70  ? 101.016 92.179  94.844  1.00 264.34 ? 70  VAL B O   1 
ATOM   3785  C CB  . VAL B 2 70  ? 101.905 93.320  91.799  1.00 141.20 ? 70  VAL B CB  1 
ATOM   3786  C CG1 . VAL B 2 70  ? 101.828 94.579  92.643  1.00 200.27 ? 70  VAL B CG1 1 
ATOM   3787  C CG2 . VAL B 2 70  ? 103.008 93.452  90.770  1.00 221.91 ? 70  VAL B CG2 1 
ATOM   3788  N N   . THR B 2 71  ? 99.710  91.763  93.058  1.00 180.57 ? 71  THR B N   1 
ATOM   3789  C CA  . THR B 2 71  ? 98.460  92.262  93.604  1.00 178.86 ? 71  THR B CA  1 
ATOM   3790  C C   . THR B 2 71  ? 97.868  91.421  94.736  1.00 180.20 ? 71  THR B C   1 
ATOM   3791  O O   . THR B 2 71  ? 97.015  91.965  95.430  1.00 190.21 ? 71  THR B O   1 
ATOM   3792  C CB  . THR B 2 71  ? 97.446  92.417  92.473  1.00 189.81 ? 71  THR B CB  1 
ATOM   3793  O OG1 . THR B 2 71  ? 97.366  91.176  91.763  1.00 201.55 ? 71  THR B OG1 1 
ATOM   3794  C CG2 . THR B 2 71  ? 97.813  93.556  91.543  1.00 208.77 ? 71  THR B CG2 1 
ATOM   3795  N N   . PRO B 2 72  ? 98.224  90.138  95.004  1.00 175.98 ? 72  PRO B N   1 
ATOM   3796  C CA  . PRO B 2 72  ? 97.724  89.427  96.187  1.00 196.93 ? 72  PRO B CA  1 
ATOM   3797  C C   . PRO B 2 72  ? 97.858  90.218  97.481  1.00 184.72 ? 72  PRO B C   1 
ATOM   3798  O O   . PRO B 2 72  ? 96.889  90.287  98.235  1.00 169.31 ? 72  PRO B O   1 
ATOM   3799  C CB  . PRO B 2 72  ? 98.561  88.124  96.240  1.00 200.78 ? 72  PRO B CB  1 
ATOM   3800  C CG  . PRO B 2 72  ? 98.865  87.880  94.784  1.00 213.40 ? 72  PRO B CG  1 
ATOM   3801  C CD  . PRO B 2 72  ? 99.085  89.265  94.211  1.00 177.99 ? 72  PRO B CD  1 
ATOM   3802  N N   . THR B 2 73  ? 99.043  90.811  97.706  1.00 148.04 ? 73  THR B N   1 
ATOM   3803  C CA  . THR B 2 73  ? 99.280  91.694  98.838  1.00 165.45 ? 73  THR B CA  1 
ATOM   3804  C C   . THR B 2 73  ? 98.331  92.903  98.829  1.00 164.63 ? 73  THR B C   1 
ATOM   3805  O O   . THR B 2 73  ? 97.922  93.379  99.888  1.00 201.56 ? 73  THR B O   1 
ATOM   3806  C CB  . THR B 2 73  ? 100.753 92.108  98.872  1.00 206.39 ? 73  THR B CB  1 
ATOM   3807  O OG1 . THR B 2 73  ? 101.494 90.896  99.044  1.00 202.48 ? 73  THR B OG1 1 
ATOM   3808  C CG2 . THR B 2 73  ? 101.076 93.121  99.954  1.00 264.98 ? 73  THR B CG2 1 
ATOM   3809  N N   . GLY B 2 74  ? 97.978  93.398  97.642  1.00 156.60 ? 74  GLY B N   1 
ATOM   3810  C CA  . GLY B 2 74  ? 97.112  94.554  97.494  1.00 201.02 ? 74  GLY B CA  1 
ATOM   3811  C C   . GLY B 2 74  ? 95.680  94.277  97.932  1.00 204.71 ? 74  GLY B C   1 
ATOM   3812  O O   . GLY B 2 74  ? 95.139  95.020  98.752  1.00 206.38 ? 74  GLY B O   1 
ATOM   3813  N N   . VAL B 2 75  ? 95.077  93.205  97.398  1.00 184.05 ? 75  VAL B N   1 
ATOM   3814  C CA  . VAL B 2 75  ? 93.710  92.854  97.766  1.00 194.67 ? 75  VAL B CA  1 
ATOM   3815  C C   . VAL B 2 75  ? 93.669  92.466  99.241  1.00 221.85 ? 75  VAL B C   1 
ATOM   3816  O O   . VAL B 2 75  ? 92.707  92.814  99.914  1.00 259.94 ? 75  VAL B O   1 
ATOM   3817  C CB  . VAL B 2 75  ? 93.097  91.750  96.875  1.00 220.84 ? 75  VAL B CB  1 
ATOM   3818  C CG1 . VAL B 2 75  ? 93.059  92.187  95.428  1.00 262.67 ? 75  VAL B CG1 1 
ATOM   3819  C CG2 . VAL B 2 75  ? 93.805  90.408  96.968  1.00 196.06 ? 75  VAL B CG2 1 
ATOM   3820  N N   . LEU B 2 76  ? 94.688  91.753  99.752  1.00 202.45 ? 76  LEU B N   1 
ATOM   3821  C CA  . LEU B 2 76  ? 94.681  91.322  101.144 1.00 186.46 ? 76  LEU B CA  1 
ATOM   3822  C C   . LEU B 2 76  ? 94.807  92.510  102.105 1.00 161.22 ? 76  LEU B C   1 
ATOM   3823  O O   . LEU B 2 76  ? 94.136  92.510  103.136 1.00 207.63 ? 76  LEU B O   1 
ATOM   3824  C CB  . LEU B 2 76  ? 95.793  90.294  101.346 1.00 177.48 ? 76  LEU B CB  1 
ATOM   3825  C CG  . LEU B 2 76  ? 95.793  89.574  102.686 1.00 178.22 ? 76  LEU B CG  1 
ATOM   3826  C CD1 . LEU B 2 76  ? 94.553  88.671  102.884 1.00 217.80 ? 76  LEU B CD1 1 
ATOM   3827  C CD2 . LEU B 2 76  ? 97.093  88.803  102.802 1.00 166.22 ? 76  LEU B CD2 1 
ATOM   3828  N N   . LYS B 2 77  ? 95.618  93.521  101.775 1.00 171.45 ? 77  LYS B N   1 
ATOM   3829  C CA  . LYS B 2 77  ? 95.755  94.713  102.606 1.00 218.31 ? 77  LYS B CA  1 
ATOM   3830  C C   . LYS B 2 77  ? 94.415  95.446  102.780 1.00 237.19 ? 77  LYS B C   1 
ATOM   3831  O O   . LYS B 2 77  ? 94.110  95.912  103.883 1.00 272.86 ? 77  LYS B O   1 
ATOM   3832  C CB  . LYS B 2 77  ? 96.826  95.629  102.010 1.00 254.24 ? 77  LYS B CB  1 
ATOM   3833  C CG  . LYS B 2 77  ? 97.164  96.854  102.848 1.00 263.96 ? 77  LYS B CG  1 
ATOM   3834  C CD  . LYS B 2 77  ? 98.442  97.554  102.402 1.00 325.97 ? 77  LYS B CD  1 
ATOM   3835  C CE  . LYS B 2 77  ? 98.381  98.196  101.025 1.00 415.24 ? 77  LYS B CE  1 
ATOM   3836  N NZ  . LYS B 2 77  ? 97.529  99.415  100.978 1.00 464.36 ? 77  LYS B NZ  1 
ATOM   3837  N N   . GLU B 2 78  ? 93.616  95.538  101.706 1.00 213.54 ? 78  GLU B N   1 
ATOM   3838  C CA  . GLU B 2 78  ? 92.342  96.256  101.726 1.00 250.48 ? 78  GLU B CA  1 
ATOM   3839  C C   . GLU B 2 78  ? 91.152  95.396  102.210 1.00 238.45 ? 78  GLU B C   1 
ATOM   3840  O O   . GLU B 2 78  ? 90.271  95.903  102.905 1.00 184.20 ? 78  GLU B O   1 
ATOM   3841  C CB  . GLU B 2 78  ? 92.110  96.817  100.323 1.00 286.28 ? 78  GLU B CB  1 
ATOM   3842  C CG  . GLU B 2 78  ? 93.209  97.738  99.793  1.00 281.75 ? 78  GLU B CG  1 
ATOM   3843  C CD  . GLU B 2 78  ? 93.579  98.904  100.691 1.00 281.84 ? 78  GLU B CD  1 
ATOM   3844  O OE1 . GLU B 2 78  ? 92.671  99.451  101.354 1.00 266.45 ? 78  GLU B OE1 1 
ATOM   3845  O OE2 . GLU B 2 78  ? 94.771  99.259  100.727 1.00 332.82 ? 78  GLU B OE2 1 
ATOM   3846  N N   . ALA B 2 79  ? 91.104  94.097  101.862 1.00 243.99 ? 79  ALA B N   1 
ATOM   3847  C CA  . ALA B 2 79  ? 90.069  93.161  102.315 1.00 244.76 ? 79  ALA B CA  1 
ATOM   3848  C C   . ALA B 2 79  ? 90.310  92.608  103.731 1.00 241.80 ? 79  ALA B C   1 
ATOM   3849  O O   . ALA B 2 79  ? 89.418  91.978  104.326 1.00 214.49 ? 79  ALA B O   1 
ATOM   3850  C CB  . ALA B 2 79  ? 89.978  92.027  101.333 1.00 246.20 ? 79  ALA B CB  1 
ATOM   3851  N N   . GLY B 2 80  ? 91.512  92.820  104.292 1.00 257.45 ? 80  GLY B N   1 
ATOM   3852  C CA  . GLY B 2 80  ? 91.774  92.558  105.703 1.00 259.73 ? 80  GLY B CA  1 
ATOM   3853  C C   . GLY B 2 80  ? 92.127  91.106  106.027 1.00 255.49 ? 80  GLY B C   1 
ATOM   3854  O O   . GLY B 2 80  ? 93.064  90.882  106.794 1.00 249.90 ? 80  GLY B O   1 
ATOM   3855  N N   . SER B 2 81  ? 91.377  90.129  105.471 1.00 215.80 ? 81  SER B N   1 
ATOM   3856  C CA  . SER B 2 81  ? 91.570  88.719  105.800 1.00 241.25 ? 81  SER B CA  1 
ATOM   3857  C C   . SER B 2 81  ? 91.196  87.832  104.613 1.00 176.76 ? 81  SER B C   1 
ATOM   3858  O O   . SER B 2 81  ? 90.335  88.244  103.844 1.00 149.02 ? 81  SER B O   1 
ATOM   3859  C CB  . SER B 2 81  ? 90.779  88.371  107.049 1.00 337.01 ? 81  SER B CB  1 
ATOM   3860  O OG  . SER B 2 81  ? 91.172  87.132  107.623 1.00 373.24 ? 81  SER B OG  1 
ATOM   3861  N N   . PRO B 2 82  ? 91.833  86.639  104.417 1.00 211.40 ? 82  PRO B N   1 
ATOM   3862  C CA  . PRO B 2 82  ? 91.715  85.856  103.178 1.00 227.40 ? 82  PRO B CA  1 
ATOM   3863  C C   . PRO B 2 82  ? 90.322  85.621  102.595 1.00 238.90 ? 82  PRO B C   1 
ATOM   3864  O O   . PRO B 2 82  ? 90.185  85.692  101.388 1.00 219.14 ? 82  PRO B O   1 
ATOM   3865  C CB  . PRO B 2 82  ? 92.336  84.496  103.550 1.00 199.15 ? 82  PRO B CB  1 
ATOM   3866  C CG  . PRO B 2 82  ? 93.415  84.868  104.515 1.00 217.21 ? 82  PRO B CG  1 
ATOM   3867  C CD  . PRO B 2 82  ? 92.752  85.954  105.347 1.00 233.92 ? 82  PRO B CD  1 
ATOM   3868  N N   . GLY B 2 83  ? 89.306  85.374  103.428 1.00 310.56 ? 83  GLY B N   1 
ATOM   3869  C CA  . GLY B 2 83  ? 87.982  84.999  102.957 1.00 319.27 ? 83  GLY B CA  1 
ATOM   3870  C C   . GLY B 2 83  ? 87.404  86.023  101.977 1.00 293.05 ? 83  GLY B C   1 
ATOM   3871  O O   . GLY B 2 83  ? 86.839  85.636  100.958 1.00 369.87 ? 83  GLY B O   1 
ATOM   3872  N N   . LEU B 2 84  ? 87.559  87.323  102.280 1.00 205.98 ? 84  LEU B N   1 
ATOM   3873  C CA  . LEU B 2 84  ? 87.047  88.371  101.410 1.00 227.35 ? 84  LEU B CA  1 
ATOM   3874  C C   . LEU B 2 84  ? 88.007  88.621  100.250 1.00 232.39 ? 84  LEU B C   1 
ATOM   3875  O O   . LEU B 2 84  ? 87.553  89.040  99.189  1.00 238.53 ? 84  LEU B O   1 
ATOM   3876  C CB  . LEU B 2 84  ? 86.786  89.634  102.232 1.00 238.07 ? 84  LEU B CB  1 
ATOM   3877  C CG  . LEU B 2 84  ? 86.134  90.814  101.508 1.00 270.38 ? 84  LEU B CG  1 
ATOM   3878  C CD1 . LEU B 2 84  ? 84.852  90.441  100.763 1.00 279.61 ? 84  LEU B CD1 1 
ATOM   3879  C CD2 . LEU B 2 84  ? 85.811  91.907  102.508 1.00 308.61 ? 84  LEU B CD2 1 
ATOM   3880  N N   . ALA B 2 85  ? 89.311  88.363  100.410 1.00 246.52 ? 85  ALA B N   1 
ATOM   3881  C CA  . ALA B 2 85  ? 90.255  88.488  99.301  1.00 274.97 ? 85  ALA B CA  1 
ATOM   3882  C C   . ALA B 2 85  ? 89.894  87.549  98.139  1.00 241.68 ? 85  ALA B C   1 
ATOM   3883  O O   . ALA B 2 85  ? 89.935  87.986  96.979  1.00 301.63 ? 85  ALA B O   1 
ATOM   3884  C CB  . ALA B 2 85  ? 91.667  88.275  99.787  1.00 243.29 ? 85  ALA B CB  1 
ATOM   3885  N N   . LEU B 2 86  ? 89.520  86.286  98.434  1.00 161.14 ? 86  LEU B N   1 
ATOM   3886  C CA  . LEU B 2 86  ? 89.099  85.354  97.393  1.00 199.02 ? 86  LEU B CA  1 
ATOM   3887  C C   . LEU B 2 86  ? 87.808  85.830  96.713  1.00 203.70 ? 86  LEU B C   1 
ATOM   3888  O O   . LEU B 2 86  ? 87.695  85.699  95.491  1.00 266.16 ? 86  LEU B O   1 
ATOM   3889  C CB  . LEU B 2 86  ? 88.954  83.944  97.971  1.00 227.68 ? 86  LEU B CB  1 
ATOM   3890  C CG  . LEU B 2 86  ? 90.225  83.330  98.574  1.00 245.49 ? 86  LEU B CG  1 
ATOM   3891  C CD1 . LEU B 2 86  ? 89.892  82.052  99.317  1.00 327.49 ? 86  LEU B CD1 1 
ATOM   3892  C CD2 . LEU B 2 86  ? 91.307  83.058  97.545  1.00 173.51 ? 86  LEU B CD2 1 
ATOM   3893  N N   . VAL B 2 87  ? 86.850  86.387  97.469  1.00 192.03 ? 87  VAL B N   1 
ATOM   3894  C CA  . VAL B 2 87  ? 85.618  86.929  96.900  1.00 264.70 ? 87  VAL B CA  1 
ATOM   3895  C C   . VAL B 2 87  ? 85.939  88.105  95.974  1.00 219.30 ? 87  VAL B C   1 
ATOM   3896  O O   . VAL B 2 87  ? 85.307  88.233  94.926  1.00 251.11 ? 87  VAL B O   1 
ATOM   3897  C CB  . VAL B 2 87  ? 84.594  87.296  98.000  1.00 359.91 ? 87  VAL B CB  1 
ATOM   3898  C CG1 . VAL B 2 87  ? 83.417  88.138  97.508  1.00 406.21 ? 87  VAL B CG1 1 
ATOM   3899  C CG2 . VAL B 2 87  ? 84.081  86.039  98.689  1.00 392.98 ? 87  VAL B CG2 1 
ATOM   3900  N N   . VAL B 2 88  ? 86.908  88.955  96.335  1.00 193.31 ? 88  VAL B N   1 
ATOM   3901  C CA  . VAL B 2 88  ? 87.314  90.050  95.461  1.00 241.12 ? 88  VAL B CA  1 
ATOM   3902  C C   . VAL B 2 88  ? 87.946  89.493  94.184  1.00 218.42 ? 88  VAL B C   1 
ATOM   3903  O O   . VAL B 2 88  ? 87.661  90.029  93.114  1.00 261.49 ? 88  VAL B O   1 
ATOM   3904  C CB  . VAL B 2 88  ? 88.217  91.068  96.184  1.00 254.50 ? 88  VAL B CB  1 
ATOM   3905  C CG1 . VAL B 2 88  ? 88.931  92.024  95.237  1.00 225.55 ? 88  VAL B CG1 1 
ATOM   3906  C CG2 . VAL B 2 88  ? 87.401  91.858  97.199  1.00 274.84 ? 88  VAL B CG2 1 
ATOM   3907  N N   . TRP B 2 89  ? 88.770  88.443  94.261  1.00 194.64 ? 89  TRP B N   1 
ATOM   3908  C CA  . TRP B 2 89  ? 89.319  87.843  93.045  1.00 215.07 ? 89  TRP B CA  1 
ATOM   3909  C C   . TRP B 2 89  ? 88.226  87.356  92.098  1.00 231.47 ? 89  TRP B C   1 
ATOM   3910  O O   . TRP B 2 89  ? 88.344  87.554  90.889  1.00 291.40 ? 89  TRP B O   1 
ATOM   3911  C CB  . TRP B 2 89  ? 90.294  86.694  93.337  1.00 191.20 ? 89  TRP B CB  1 
ATOM   3912  C CG  . TRP B 2 89  ? 91.662  87.210  93.651  1.00 205.22 ? 89  TRP B CG  1 
ATOM   3913  C CD1 . TRP B 2 89  ? 92.294  87.171  94.849  1.00 233.29 ? 89  TRP B CD1 1 
ATOM   3914  C CD2 . TRP B 2 89  ? 92.560  87.873  92.743  1.00 204.59 ? 89  TRP B CD2 1 
ATOM   3915  N NE1 . TRP B 2 89  ? 93.524  87.758  94.750  1.00 217.07 ? 89  TRP B NE1 1 
ATOM   3916  C CE2 . TRP B 2 89  ? 93.718  88.200  93.471  1.00 214.75 ? 89  TRP B CE2 1 
ATOM   3917  C CE3 . TRP B 2 89  ? 92.495  88.222  91.394  1.00 228.57 ? 89  TRP B CE3 1 
ATOM   3918  C CZ2 . TRP B 2 89  ? 94.802  88.855  92.887  1.00 229.45 ? 89  TRP B CZ2 1 
ATOM   3919  C CZ3 . TRP B 2 89  ? 93.564  88.862  90.814  1.00 225.72 ? 89  TRP B CZ3 1 
ATOM   3920  C CH2 . TRP B 2 89  ? 94.700  89.179  91.554  1.00 212.11 ? 89  TRP B CH2 1 
ATOM   3921  N N   . ALA B 2 90  ? 87.185  86.725  92.647  1.00 187.99 ? 90  ALA B N   1 
ATOM   3922  C CA  . ALA B 2 90  ? 86.054  86.295  91.846  1.00 212.27 ? 90  ALA B CA  1 
ATOM   3923  C C   . ALA B 2 90  ? 85.318  87.503  91.249  1.00 198.81 ? 90  ALA B C   1 
ATOM   3924  O O   . ALA B 2 90  ? 85.000  87.490  90.061  1.00 212.00 ? 90  ALA B O   1 
ATOM   3925  C CB  . ALA B 2 90  ? 85.146  85.419  92.680  1.00 277.53 ? 90  ALA B CB  1 
ATOM   3926  N N   . ALA B 2 91  ? 85.042  88.537  92.062  1.00 193.15 ? 91  ALA B N   1 
ATOM   3927  C CA  . ALA B 2 91  ? 84.313  89.725  91.621  1.00 249.48 ? 91  ALA B CA  1 
ATOM   3928  C C   . ALA B 2 91  ? 85.034  90.430  90.469  1.00 226.41 ? 91  ALA B C   1 
ATOM   3929  O O   . ALA B 2 91  ? 84.385  90.895  89.536  1.00 218.73 ? 91  ALA B O   1 
ATOM   3930  C CB  . ALA B 2 91  ? 84.092  90.652  92.795  1.00 308.76 ? 91  ALA B CB  1 
ATOM   3931  N N   . CYS B 2 92  ? 86.368  90.480  90.536  1.00 243.78 ? 92  CYS B N   1 
ATOM   3932  C CA  . CYS B 2 92  ? 87.189  91.010  89.456  1.00 250.40 ? 92  CYS B CA  1 
ATOM   3933  C C   . CYS B 2 92  ? 87.080  90.178  88.179  1.00 236.54 ? 92  CYS B C   1 
ATOM   3934  O O   . CYS B 2 92  ? 87.031  90.748  87.083  1.00 289.75 ? 92  CYS B O   1 
ATOM   3935  C CB  . CYS B 2 92  ? 88.623  91.104  89.942  1.00 262.61 ? 92  CYS B CB  1 
ATOM   3936  S SG  . CYS B 2 92  ? 88.712  92.281  91.304  1.00 343.78 ? 92  CYS B SG  1 
ATOM   3937  N N   . GLY B 2 93  ? 87.027  88.847  88.325  1.00 180.86 ? 93  GLY B N   1 
ATOM   3938  C CA  . GLY B 2 93  ? 86.720  87.950  87.221  1.00 202.15 ? 93  GLY B CA  1 
ATOM   3939  C C   . GLY B 2 93  ? 85.401  88.300  86.527  1.00 215.02 ? 93  GLY B C   1 
ATOM   3940  O O   . GLY B 2 93  ? 85.384  88.511  85.311  1.00 256.55 ? 93  GLY B O   1 
ATOM   3941  N N   . VAL B 2 94  ? 84.324  88.372  87.316  1.00 207.91 ? 94  VAL B N   1 
ATOM   3942  C CA  . VAL B 2 94  ? 82.985  88.631  86.803  1.00 252.90 ? 94  VAL B CA  1 
ATOM   3943  C C   . VAL B 2 94  ? 82.930  90.014  86.148  1.00 227.86 ? 94  VAL B C   1 
ATOM   3944  O O   . VAL B 2 94  ? 82.345  90.132  85.080  1.00 227.71 ? 94  VAL B O   1 
ATOM   3945  C CB  . VAL B 2 94  ? 81.920  88.438  87.906  1.00 352.63 ? 94  VAL B CB  1 
ATOM   3946  C CG1 . VAL B 2 94  ? 80.523  88.925  87.516  1.00 387.51 ? 94  VAL B CG1 1 
ATOM   3947  C CG2 . VAL B 2 94  ? 81.877  86.976  88.330  1.00 403.80 ? 94  VAL B CG2 1 
ATOM   3948  N N   . PHE B 2 95  ? 83.538  91.041  86.754  1.00 209.00 ? 95  PHE B N   1 
ATOM   3949  C CA  . PHE B 2 95  ? 83.625  92.354  86.128  1.00 202.15 ? 95  PHE B CA  1 
ATOM   3950  C C   . PHE B 2 95  ? 84.364  92.287  84.789  1.00 168.29 ? 95  PHE B C   1 
ATOM   3951  O O   . PHE B 2 95  ? 83.941  92.935  83.838  1.00 188.12 ? 95  PHE B O   1 
ATOM   3952  C CB  . PHE B 2 95  ? 84.301  93.324  87.092  1.00 245.06 ? 95  PHE B CB  1 
ATOM   3953  C CG  . PHE B 2 95  ? 84.454  94.744  86.613  1.00 262.21 ? 95  PHE B CG  1 
ATOM   3954  C CD1 . PHE B 2 95  ? 85.511  95.100  85.781  1.00 302.36 ? 95  PHE B CD1 1 
ATOM   3955  C CD2 . PHE B 2 95  ? 83.549  95.732  86.999  1.00 252.84 ? 95  PHE B CD2 1 
ATOM   3956  C CE1 . PHE B 2 95  ? 85.666  96.411  85.349  1.00 340.77 ? 95  PHE B CE1 1 
ATOM   3957  C CE2 . PHE B 2 95  ? 83.701  97.041  86.557  1.00 289.79 ? 95  PHE B CE2 1 
ATOM   3958  C CZ  . PHE B 2 95  ? 84.756  97.379  85.730  1.00 351.79 ? 95  PHE B CZ  1 
ATOM   3959  N N   . SER B 2 96  ? 85.448  91.510  84.704  1.00 195.98 ? 96  SER B N   1 
ATOM   3960  C CA  . SER B 2 96  ? 86.165  91.318  83.441  1.00 230.31 ? 96  SER B CA  1 
ATOM   3961  C C   . SER B 2 96  ? 85.317  90.606  82.379  1.00 213.18 ? 96  SER B C   1 
ATOM   3962  O O   . SER B 2 96  ? 85.433  90.974  81.210  1.00 199.72 ? 96  SER B O   1 
ATOM   3963  C CB  . SER B 2 96  ? 87.473  90.614  83.650  1.00 229.67 ? 96  SER B CB  1 
ATOM   3964  O OG  . SER B 2 96  ? 88.271  91.364  84.545  1.00 227.59 ? 96  SER B OG  1 
ATOM   3965  N N   . ILE B 2 97  ? 84.478  89.619  82.751  1.00 207.25 ? 97  ILE B N   1 
ATOM   3966  C CA  . ILE B 2 97  ? 83.579  88.970  81.794  1.00 229.43 ? 97  ILE B CA  1 
ATOM   3967  C C   . ILE B 2 97  ? 82.622  89.997  81.175  1.00 212.74 ? 97  ILE B C   1 
ATOM   3968  O O   . ILE B 2 97  ? 82.471  90.021  79.947  1.00 195.98 ? 97  ILE B O   1 
ATOM   3969  C CB  . ILE B 2 97  ? 82.834  87.784  82.434  1.00 285.68 ? 97  ILE B CB  1 
ATOM   3970  C CG1 . ILE B 2 97  ? 83.783  86.616  82.708  1.00 275.99 ? 97  ILE B CG1 1 
ATOM   3971  C CG2 . ILE B 2 97  ? 81.659  87.332  81.569  1.00 343.32 ? 97  ILE B CG2 1 
ATOM   3972  C CD1 . ILE B 2 97  ? 83.307  85.647  83.763  1.00 336.56 ? 97  ILE B CD1 1 
ATOM   3973  N N   . VAL B 2 98  ? 82.002  90.840  82.008  1.00 180.52 ? 98  VAL B N   1 
ATOM   3974  C CA  . VAL B 2 98  ? 81.120  91.895  81.521  1.00 199.05 ? 98  VAL B CA  1 
ATOM   3975  C C   . VAL B 2 98  ? 81.881  92.945  80.689  1.00 204.16 ? 98  VAL B C   1 
ATOM   3976  O O   . VAL B 2 98  ? 81.364  93.416  79.682  1.00 240.83 ? 98  VAL B O   1 
ATOM   3977  C CB  . VAL B 2 98  ? 80.318  92.522  82.679  1.00 253.81 ? 98  VAL B CB  1 
ATOM   3978  C CG1 . VAL B 2 98  ? 79.347  93.574  82.185  1.00 313.43 ? 98  VAL B CG1 1 
ATOM   3979  C CG2 . VAL B 2 98  ? 79.540  91.461  83.448  1.00 308.61 ? 98  VAL B CG2 1 
ATOM   3980  N N   . GLY B 2 99  ? 83.097  93.322  81.090  1.00 177.12 ? 99  GLY B N   1 
ATOM   3981  C CA  . GLY B 2 99  ? 83.937  94.231  80.315  1.00 185.60 ? 99  GLY B CA  1 
ATOM   3982  C C   . GLY B 2 99  ? 84.348  93.675  78.946  1.00 208.00 ? 99  GLY B C   1 
ATOM   3983  O O   . GLY B 2 99  ? 84.210  94.367  77.933  1.00 227.03 ? 99  GLY B O   1 
ATOM   3984  N N   . ALA B 2 100 ? 84.831  92.420  78.924  1.00 202.73 ? 100 ALA B N   1 
ATOM   3985  C CA  . ALA B 2 100 ? 85.313  91.760  77.715  1.00 240.19 ? 100 ALA B CA  1 
ATOM   3986  C C   . ALA B 2 100 ? 84.206  91.632  76.662  1.00 258.02 ? 100 ALA B C   1 
ATOM   3987  O O   . ALA B 2 100 ? 84.475  91.906  75.489  1.00 276.12 ? 100 ALA B O   1 
ATOM   3988  C CB  . ALA B 2 100 ? 85.913  90.410  78.046  1.00 249.25 ? 100 ALA B CB  1 
ATOM   3989  N N   . LEU B 2 101 ? 82.979  91.233  77.049  1.00 232.35 ? 101 LEU B N   1 
ATOM   3990  C CA  . LEU B 2 101 ? 81.925  91.083  76.052  1.00 238.52 ? 101 LEU B CA  1 
ATOM   3991  C C   . LEU B 2 101 ? 81.504  92.450  75.478  1.00 253.33 ? 101 LEU B C   1 
ATOM   3992  O O   . LEU B 2 101 ? 81.128  92.516  74.300  1.00 305.76 ? 101 LEU B O   1 
ATOM   3993  C CB  . LEU B 2 101 ? 80.747  90.275  76.614  1.00 269.56 ? 101 LEU B CB  1 
ATOM   3994  C CG  . LEU B 2 101 ? 79.969  90.800  77.821  1.00 302.03 ? 101 LEU B CG  1 
ATOM   3995  C CD1 . LEU B 2 101 ? 78.861  91.800  77.441  1.00 278.75 ? 101 LEU B CD1 1 
ATOM   3996  C CD2 . LEU B 2 101 ? 79.377  89.611  78.571  1.00 370.35 ? 101 LEU B CD2 1 
ATOM   3997  N N   . CYS B 2 102 ? 81.567  93.547  76.260  1.00 208.75 ? 102 CYS B N   1 
ATOM   3998  C CA  . CYS B 2 102 ? 81.310  94.874  75.699  1.00 238.48 ? 102 CYS B CA  1 
ATOM   3999  C C   . CYS B 2 102 ? 82.402  95.261  74.691  1.00 230.99 ? 102 CYS B C   1 
ATOM   4000  O O   . CYS B 2 102 ? 82.133  95.904  73.666  1.00 216.68 ? 102 CYS B O   1 
ATOM   4001  C CB  . CYS B 2 102 ? 81.151  95.896  76.816  1.00 259.97 ? 102 CYS B CB  1 
ATOM   4002  S SG  . CYS B 2 102 ? 79.779  95.475  77.927  1.00 303.64 ? 102 CYS B SG  1 
ATOM   4003  N N   . TYR B 2 103 ? 83.644  94.848  74.967  1.00 226.07 ? 103 TYR B N   1 
ATOM   4004  C CA  . TYR B 2 103 ? 84.743  95.059  74.032  1.00 264.82 ? 103 TYR B CA  1 
ATOM   4005  C C   . TYR B 2 103 ? 84.727  94.086  72.845  1.00 270.83 ? 103 TYR B C   1 
ATOM   4006  O O   . TYR B 2 103 ? 85.332  94.399  71.819  1.00 251.46 ? 103 TYR B O   1 
ATOM   4007  C CB  . TYR B 2 103 ? 86.058  95.024  74.810  1.00 282.29 ? 103 TYR B CB  1 
ATOM   4008  C CG  . TYR B 2 103 ? 86.440  96.451  75.152  1.00 283.19 ? 103 TYR B CG  1 
ATOM   4009  C CD1 . TYR B 2 103 ? 85.722  97.209  76.079  1.00 280.63 ? 103 TYR B CD1 1 
ATOM   4010  C CD2 . TYR B 2 103 ? 87.508  97.049  74.512  1.00 272.73 ? 103 TYR B CD2 1 
ATOM   4011  C CE1 . TYR B 2 103 ? 86.073  98.521  76.377  1.00 226.57 ? 103 TYR B CE1 1 
ATOM   4012  C CE2 . TYR B 2 103 ? 87.870  98.351  74.802  1.00 281.53 ? 103 TYR B CE2 1 
ATOM   4013  C CZ  . TYR B 2 103 ? 87.156  99.093  75.733  1.00 258.78 ? 103 TYR B CZ  1 
ATOM   4014  O OH  . TYR B 2 103 ? 87.536  100.376 75.997  1.00 270.76 ? 103 TYR B OH  1 
ATOM   4015  N N   . ALA B 2 104 ? 84.062  92.926  72.965  1.00 252.42 ? 104 ALA B N   1 
ATOM   4016  C CA  . ALA B 2 104 ? 83.756  92.091  71.808  1.00 247.48 ? 104 ALA B CA  1 
ATOM   4017  C C   . ALA B 2 104 ? 82.837  92.835  70.835  1.00 249.10 ? 104 ALA B C   1 
ATOM   4018  O O   . ALA B 2 104 ? 83.001  92.692  69.618  1.00 236.26 ? 104 ALA B O   1 
ATOM   4019  C CB  . ALA B 2 104 ? 83.140  90.787  72.254  1.00 253.77 ? 104 ALA B CB  1 
ATOM   4020  N N   . GLU B 2 105 ? 81.877  93.618  71.371  1.00 245.75 ? 105 GLU B N   1 
ATOM   4021  C CA  . GLU B 2 105 ? 81.028  94.466  70.543  1.00 260.30 ? 105 GLU B CA  1 
ATOM   4022  C C   . GLU B 2 105 ? 81.864  95.573  69.885  1.00 269.58 ? 105 GLU B C   1 
ATOM   4023  O O   . GLU B 2 105 ? 81.988  95.576  68.658  1.00 304.95 ? 105 GLU B O   1 
ATOM   4024  C CB  . GLU B 2 105 ? 79.815  94.996  71.317  1.00 212.61 ? 105 GLU B CB  1 
ATOM   4025  C CG  . GLU B 2 105 ? 78.856  95.764  70.401  1.00 300.11 ? 105 GLU B CG  1 
ATOM   4026  C CD  . GLU B 2 105 ? 77.388  95.814  70.798  1.00 399.49 ? 105 GLU B CD  1 
ATOM   4027  O OE1 . GLU B 2 105 ? 76.925  94.882  71.496  1.00 449.57 ? 105 GLU B OE1 1 
ATOM   4028  O OE2 . GLU B 2 105 ? 76.698  96.793  70.409  1.00 464.13 ? 105 GLU B OE2 1 
ATOM   4029  N N   . LEU B 2 106 ? 82.459  96.498  70.651  1.00 223.15 ? 106 LEU B N   1 
ATOM   4030  C CA  . LEU B 2 106 ? 83.205  97.594  70.030  1.00 233.04 ? 106 LEU B CA  1 
ATOM   4031  C C   . LEU B 2 106 ? 84.323  97.104  69.088  1.00 249.98 ? 106 LEU B C   1 
ATOM   4032  O O   . LEU B 2 106 ? 84.550  97.710  68.033  1.00 213.64 ? 106 LEU B O   1 
ATOM   4033  C CB  . LEU B 2 106 ? 83.777  98.497  71.124  1.00 272.70 ? 106 LEU B CB  1 
ATOM   4034  C CG  . LEU B 2 106 ? 82.776  99.426  71.808  1.00 300.01 ? 106 LEU B CG  1 
ATOM   4035  C CD1 . LEU B 2 106 ? 83.469  100.170 72.933  1.00 296.97 ? 106 LEU B CD1 1 
ATOM   4036  C CD2 . LEU B 2 106 ? 82.140  100.407 70.824  1.00 307.49 ? 106 LEU B CD2 1 
ATOM   4037  N N   . GLY B 2 107 ? 85.000  96.000  69.447  1.00 309.11 ? 107 GLY B N   1 
ATOM   4038  C CA  . GLY B 2 107 ? 86.032  95.383  68.619  1.00 348.01 ? 107 GLY B CA  1 
ATOM   4039  C C   . GLY B 2 107 ? 85.551  94.699  67.333  1.00 334.97 ? 107 GLY B C   1 
ATOM   4040  O O   . GLY B 2 107 ? 86.390  94.173  66.596  1.00 323.59 ? 107 GLY B O   1 
ATOM   4041  N N   . THR B 2 108 ? 84.230  94.689  67.071  1.00 304.43 ? 108 THR B N   1 
ATOM   4042  C CA  . THR B 2 108 ? 83.658  94.166  65.835  1.00 309.96 ? 108 THR B CA  1 
ATOM   4043  C C   . THR B 2 108 ? 82.691  95.134  65.139  1.00 280.49 ? 108 THR B C   1 
ATOM   4044  O O   . THR B 2 108 ? 82.446  94.926  63.949  1.00 323.94 ? 108 THR B O   1 
ATOM   4045  C CB  . THR B 2 108 ? 82.946  92.826  66.082  1.00 339.11 ? 108 THR B CB  1 
ATOM   4046  O OG1 . THR B 2 108 ? 81.896  92.975  67.046  1.00 248.28 ? 108 THR B OG1 1 
ATOM   4047  C CG2 . THR B 2 108 ? 83.899  91.736  66.532  1.00 379.37 ? 108 THR B CG2 1 
ATOM   4048  N N   . THR B 2 109 ? 82.141  96.155  65.827  1.00 233.88 ? 109 THR B N   1 
ATOM   4049  C CA  . THR B 2 109 ? 81.264  97.128  65.176  1.00 297.05 ? 109 THR B CA  1 
ATOM   4050  C C   . THR B 2 109 ? 82.060  98.225  64.465  1.00 316.29 ? 109 THR B C   1 
ATOM   4051  O O   . THR B 2 109 ? 81.834  98.458  63.277  1.00 354.20 ? 109 THR B O   1 
ATOM   4052  C CB  . THR B 2 109 ? 80.243  97.748  66.143  1.00 313.55 ? 109 THR B CB  1 
ATOM   4053  O OG1 . THR B 2 109 ? 80.891  98.458  67.197  1.00 284.05 ? 109 THR B OG1 1 
ATOM   4054  C CG2 . THR B 2 109 ? 79.319  96.711  66.750  1.00 365.36 ? 109 THR B CG2 1 
ATOM   4055  N N   . ILE B 2 110 ? 82.972  98.905  65.178  1.00 317.22 ? 110 ILE B N   1 
ATOM   4056  C CA  . ILE B 2 110 ? 83.745  100.009 64.607  1.00 347.90 ? 110 ILE B CA  1 
ATOM   4057  C C   . ILE B 2 110 ? 84.985  99.466  63.875  1.00 340.40 ? 110 ILE B C   1 
ATOM   4058  O O   . ILE B 2 110 ? 85.315  99.958  62.789  1.00 244.53 ? 110 ILE B O   1 
ATOM   4059  C CB  . ILE B 2 110 ? 84.069  101.063 65.696  1.00 367.11 ? 110 ILE B CB  1 
ATOM   4060  C CG1 . ILE B 2 110 ? 82.784  101.712 66.234  1.00 353.43 ? 110 ILE B CG1 1 
ATOM   4061  C CG2 . ILE B 2 110 ? 85.040  102.123 65.182  1.00 360.03 ? 110 ILE B CG2 1 
ATOM   4062  C CD1 . ILE B 2 110 ? 82.956  102.601 67.458  1.00 360.23 ? 110 ILE B CD1 1 
ATOM   4063  N N   . SER B 2 111 ? 85.680  98.482  64.489  1.00 369.14 ? 111 SER B N   1 
ATOM   4064  C CA  . SER B 2 111 ? 86.772  97.695  63.898  1.00 359.12 ? 111 SER B CA  1 
ATOM   4065  C C   . SER B 2 111 ? 88.006  98.492  63.422  1.00 390.76 ? 111 SER B C   1 
ATOM   4066  O O   . SER B 2 111 ? 88.963  97.884  62.937  1.00 383.69 ? 111 SER B O   1 
ATOM   4067  C CB  . SER B 2 111 ? 86.222  96.799  62.807  1.00 297.31 ? 111 SER B CB  1 
ATOM   4068  O OG  . SER B 2 111 ? 85.345  95.846  63.389  1.00 310.28 ? 111 SER B OG  1 
ATOM   4069  N N   . LYS B 2 112 ? 88.034  99.831  63.571  1.00 390.47 ? 112 LYS B N   1 
ATOM   4070  C CA  . LYS B 2 112 ? 89.175  100.649 63.170  1.00 370.04 ? 112 LYS B CA  1 
ATOM   4071  C C   . LYS B 2 112 ? 90.400  100.302 64.033  1.00 391.23 ? 112 LYS B C   1 
ATOM   4072  O O   . LYS B 2 112 ? 90.292  100.186 65.248  1.00 377.79 ? 112 LYS B O   1 
ATOM   4073  C CB  . LYS B 2 112 ? 88.810  102.135 63.285  1.00 341.01 ? 112 LYS B CB  1 
ATOM   4074  C CG  . LYS B 2 112 ? 89.775  103.101 62.608  1.00 359.23 ? 112 LYS B CG  1 
ATOM   4075  C CD  . LYS B 2 112 ? 89.628  104.569 63.020  1.00 402.80 ? 112 LYS B CD  1 
ATOM   4076  C CE  . LYS B 2 112 ? 88.230  105.155 62.933  1.00 449.83 ? 112 LYS B CE  1 
ATOM   4077  N NZ  . LYS B 2 112 ? 87.758  105.308 61.536  1.00 479.69 ? 112 LYS B NZ  1 
ATOM   4078  N N   . SER B 2 113 ? 91.575  100.131 63.405  1.00 414.32 ? 113 SER B N   1 
ATOM   4079  C CA  . SER B 2 113 ? 92.786  99.685  64.095  1.00 429.48 ? 113 SER B CA  1 
ATOM   4080  C C   . SER B 2 113 ? 93.368  100.757 65.029  1.00 411.75 ? 113 SER B C   1 
ATOM   4081  O O   . SER B 2 113 ? 93.246  101.950 64.753  1.00 376.07 ? 113 SER B O   1 
ATOM   4082  C CB  . SER B 2 113 ? 93.830  99.254  63.095  1.00 455.17 ? 113 SER B CB  1 
ATOM   4083  O OG  . SER B 2 113 ? 93.313  98.259  62.223  1.00 424.23 ? 113 SER B OG  1 
ATOM   4084  N N   . GLY B 2 114 ? 94.012  100.316 66.128  1.00 427.40 ? 114 GLY B N   1 
ATOM   4085  C CA  . GLY B 2 114 ? 94.837  101.169 66.984  1.00 421.63 ? 114 GLY B CA  1 
ATOM   4086  C C   . GLY B 2 114 ? 94.430  101.220 68.462  1.00 399.94 ? 114 GLY B C   1 
ATOM   4087  O O   . GLY B 2 114 ? 95.106  101.894 69.241  1.00 323.51 ? 114 GLY B O   1 
ATOM   4088  N N   . GLY B 2 115 ? 93.347  100.526 68.861  1.00 420.12 ? 115 GLY B N   1 
ATOM   4089  C CA  . GLY B 2 115 ? 92.829  100.566 70.228  1.00 400.62 ? 115 GLY B CA  1 
ATOM   4090  C C   . GLY B 2 115 ? 91.750  101.636 70.416  1.00 350.23 ? 115 GLY B C   1 
ATOM   4091  O O   . GLY B 2 115 ? 91.253  102.182 69.435  1.00 338.04 ? 115 GLY B O   1 
ATOM   4092  N N   . ASP B 2 116 ? 91.402  101.938 71.681  1.00 326.54 ? 116 ASP B N   1 
ATOM   4093  C CA  . ASP B 2 116 ? 90.279  102.800 72.053  1.00 321.65 ? 116 ASP B CA  1 
ATOM   4094  C C   . ASP B 2 116 ? 90.225  104.137 71.304  1.00 338.26 ? 116 ASP B C   1 
ATOM   4095  O O   . ASP B 2 116 ? 89.140  104.601 70.947  1.00 376.02 ? 116 ASP B O   1 
ATOM   4096  C CB  . ASP B 2 116 ? 90.319  103.144 73.543  1.00 324.42 ? 116 ASP B CB  1 
ATOM   4097  C CG  . ASP B 2 116 ? 90.022  102.010 74.510  1.00 370.48 ? 116 ASP B CG  1 
ATOM   4098  O OD1 . ASP B 2 116 ? 89.326  101.066 74.103  1.00 448.51 ? 116 ASP B OD1 1 
ATOM   4099  O OD2 . ASP B 2 116 ? 90.498  102.085 75.668  1.00 326.73 ? 116 ASP B OD2 1 
ATOM   4100  N N   . TYR B 2 117 ? 91.387  104.760 71.076  1.00 334.94 ? 117 TYR B N   1 
ATOM   4101  C CA  . TYR B 2 117 ? 91.486  106.012 70.333  1.00 334.72 ? 117 TYR B CA  1 
ATOM   4102  C C   . TYR B 2 117 ? 90.779  105.927 68.974  1.00 333.75 ? 117 TYR B C   1 
ATOM   4103  O O   . TYR B 2 117 ? 90.091  106.869 68.578  1.00 389.94 ? 117 TYR B O   1 
ATOM   4104  C CB  . TYR B 2 117 ? 92.974  106.337 70.205  1.00 323.14 ? 117 TYR B CB  1 
ATOM   4105  C CG  . TYR B 2 117 ? 93.310  107.443 69.221  1.00 308.74 ? 117 TYR B CG  1 
ATOM   4106  C CD1 . TYR B 2 117 ? 93.129  108.778 69.559  1.00 282.84 ? 117 TYR B CD1 1 
ATOM   4107  C CD2 . TYR B 2 117 ? 93.799  107.143 67.949  1.00 277.71 ? 117 TYR B CD2 1 
ATOM   4108  C CE1 . TYR B 2 117 ? 93.442  109.791 68.663  1.00 302.48 ? 117 TYR B CE1 1 
ATOM   4109  C CE2 . TYR B 2 117 ? 94.115  108.143 67.041  1.00 256.82 ? 117 TYR B CE2 1 
ATOM   4110  C CZ  . TYR B 2 117 ? 93.931  109.472 67.399  1.00 327.52 ? 117 TYR B CZ  1 
ATOM   4111  O OH  . TYR B 2 117 ? 94.250  110.449 66.494  1.00 350.90 ? 117 TYR B OH  1 
ATOM   4112  N N   . ALA B 2 118 ? 90.945  104.794 68.278  1.00 273.24 ? 118 ALA B N   1 
ATOM   4113  C CA  . ALA B 2 118 ? 90.285  104.523 67.007  1.00 277.18 ? 118 ALA B CA  1 
ATOM   4114  C C   . ALA B 2 118 ? 88.750  104.557 67.113  1.00 293.16 ? 118 ALA B C   1 
ATOM   4115  O O   . ALA B 2 118 ? 88.095  104.919 66.135  1.00 315.94 ? 118 ALA B O   1 
ATOM   4116  C CB  . ALA B 2 118 ? 90.782  103.196 66.477  1.00 290.13 ? 118 ALA B CB  1 
ATOM   4117  N N   . TYR B 2 119 ? 88.175  104.191 68.278  1.00 295.70 ? 119 TYR B N   1 
ATOM   4118  C CA  . TYR B 2 119 ? 86.735  104.275 68.539  1.00 304.73 ? 119 TYR B CA  1 
ATOM   4119  C C   . TYR B 2 119 ? 86.343  105.717 68.875  1.00 314.35 ? 119 TYR B C   1 
ATOM   4120  O O   . TYR B 2 119 ? 85.299  106.195 68.416  1.00 352.21 ? 119 TYR B O   1 
ATOM   4121  C CB  . TYR B 2 119 ? 86.273  103.321 69.657  1.00 278.63 ? 119 TYR B CB  1 
ATOM   4122  C CG  . TYR B 2 119 ? 86.771  101.879 69.558  1.00 304.46 ? 119 TYR B CG  1 
ATOM   4123  C CD1 . TYR B 2 119 ? 87.053  101.277 68.328  1.00 319.70 ? 119 TYR B CD1 1 
ATOM   4124  C CD2 . TYR B 2 119 ? 86.978  101.107 70.703  1.00 351.42 ? 119 TYR B CD2 1 
ATOM   4125  C CE1 . TYR B 2 119 ? 87.516  99.969  68.247  1.00 297.48 ? 119 TYR B CE1 1 
ATOM   4126  C CE2 . TYR B 2 119 ? 87.440  99.797  70.630  1.00 348.48 ? 119 TYR B CE2 1 
ATOM   4127  C CZ  . TYR B 2 119 ? 87.713  99.224  69.396  1.00 272.38 ? 119 TYR B CZ  1 
ATOM   4128  O OH  . TYR B 2 119 ? 88.168  97.941  69.270  1.00 179.67 ? 119 TYR B OH  1 
ATOM   4129  N N   . MET B 2 120 ? 87.174  106.416 69.668  1.00 286.06 ? 120 MET B N   1 
ATOM   4130  C CA  . MET B 2 120 ? 86.889  107.787 70.081  1.00 278.63 ? 120 MET B CA  1 
ATOM   4131  C C   . MET B 2 120 ? 86.788  108.739 68.882  1.00 314.19 ? 120 MET B C   1 
ATOM   4132  O O   . MET B 2 120 ? 85.995  109.678 68.949  1.00 339.37 ? 120 MET B O   1 
ATOM   4133  C CB  . MET B 2 120 ? 87.954  108.310 71.049  1.00 279.08 ? 120 MET B CB  1 
ATOM   4134  C CG  . MET B 2 120 ? 87.995  107.564 72.375  1.00 347.00 ? 120 MET B CG  1 
ATOM   4135  S SD  . MET B 2 120 ? 86.645  107.931 73.539  1.00 344.91 ? 120 MET B SD  1 
ATOM   4136  C CE  . MET B 2 120 ? 86.897  106.601 74.709  1.00 333.87 ? 120 MET B CE  1 
ATOM   4137  N N   . LEU B 2 121 ? 87.561  108.502 67.801  1.00 330.16 ? 121 LEU B N   1 
ATOM   4138  C CA  . LEU B 2 121 ? 87.454  109.264 66.554  1.00 315.46 ? 121 LEU B CA  1 
ATOM   4139  C C   . LEU B 2 121 ? 86.045  109.216 65.950  1.00 351.23 ? 121 LEU B C   1 
ATOM   4140  O O   . LEU B 2 121 ? 85.626  110.206 65.352  1.00 342.86 ? 121 LEU B O   1 
ATOM   4141  C CB  . LEU B 2 121 ? 88.480  108.750 65.533  1.00 267.42 ? 121 LEU B CB  1 
ATOM   4142  C CG  . LEU B 2 121 ? 89.946  109.039 65.865  1.00 348.55 ? 121 LEU B CG  1 
ATOM   4143  C CD1 . LEU B 2 121 ? 90.887  108.277 64.936  1.00 334.13 ? 121 LEU B CD1 1 
ATOM   4144  C CD2 . LEU B 2 121 ? 90.259  110.540 65.824  1.00 408.18 ? 121 LEU B CD2 1 
ATOM   4145  N N   . GLU B 2 122 ? 85.324  108.090 66.099  1.00 372.17 ? 122 GLU B N   1 
ATOM   4146  C CA  . GLU B 2 122 ? 83.966  107.940 65.580  1.00 362.98 ? 122 GLU B CA  1 
ATOM   4147  C C   . GLU B 2 122 ? 82.910  108.477 66.547  1.00 320.29 ? 122 GLU B C   1 
ATOM   4148  O O   . GLU B 2 122 ? 81.958  109.128 66.106  1.00 285.00 ? 122 GLU B O   1 
ATOM   4149  C CB  . GLU B 2 122 ? 83.692  106.469 65.245  1.00 329.39 ? 122 GLU B CB  1 
ATOM   4150  C CG  . GLU B 2 122 ? 84.567  105.948 64.111  1.00 395.35 ? 122 GLU B CG  1 
ATOM   4151  C CD  . GLU B 2 122 ? 84.443  106.673 62.778  1.00 446.43 ? 122 GLU B CD  1 
ATOM   4152  O OE1 . GLU B 2 122 ? 83.412  107.340 62.557  1.00 448.07 ? 122 GLU B OE1 1 
ATOM   4153  O OE2 . GLU B 2 122 ? 85.381  106.577 61.964  1.00 489.43 ? 122 GLU B OE2 1 
ATOM   4154  N N   . VAL B 2 123 ? 83.068  108.205 67.850  1.00 307.76 ? 123 VAL B N   1 
ATOM   4155  C CA  . VAL B 2 123 ? 82.043  108.524 68.840  1.00 311.42 ? 123 VAL B CA  1 
ATOM   4156  C C   . VAL B 2 123 ? 82.100  110.009 69.253  1.00 284.96 ? 123 VAL B C   1 
ATOM   4157  O O   . VAL B 2 123 ? 81.047  110.575 69.569  1.00 264.67 ? 123 VAL B O   1 
ATOM   4158  C CB  . VAL B 2 123 ? 82.134  107.553 70.045  1.00 338.66 ? 123 VAL B CB  1 
ATOM   4159  C CG1 . VAL B 2 123 ? 81.082  107.833 71.114  1.00 346.32 ? 123 VAL B CG1 1 
ATOM   4160  C CG2 . VAL B 2 123 ? 82.028  106.091 69.611  1.00 312.35 ? 123 VAL B CG2 1 
ATOM   4161  N N   . TYR B 2 124 ? 83.296  110.635 69.260  1.00 298.50 ? 124 TYR B N   1 
ATOM   4162  C CA  . TYR B 2 124 ? 83.490  111.989 69.782  1.00 321.64 ? 124 TYR B CA  1 
ATOM   4163  C C   . TYR B 2 124 ? 84.344  112.890 68.874  1.00 321.68 ? 124 TYR B C   1 
ATOM   4164  O O   . TYR B 2 124 ? 84.055  114.082 68.762  1.00 318.92 ? 124 TYR B O   1 
ATOM   4165  C CB  . TYR B 2 124 ? 84.156  111.905 71.160  1.00 349.10 ? 124 TYR B CB  1 
ATOM   4166  C CG  . TYR B 2 124 ? 83.466  111.058 72.224  1.00 361.96 ? 124 TYR B CG  1 
ATOM   4167  C CD1 . TYR B 2 124 ? 82.415  111.550 73.001  1.00 315.99 ? 124 TYR B CD1 1 
ATOM   4168  C CD2 . TYR B 2 124 ? 83.871  109.745 72.451  1.00 404.73 ? 124 TYR B CD2 1 
ATOM   4169  C CE1 . TYR B 2 124 ? 81.794  110.764 73.969  1.00 262.55 ? 124 TYR B CE1 1 
ATOM   4170  C CE2 . TYR B 2 124 ? 83.260  108.951 73.417  1.00 380.38 ? 124 TYR B CE2 1 
ATOM   4171  C CZ  . TYR B 2 124 ? 82.216  109.457 74.180  1.00 296.99 ? 124 TYR B CZ  1 
ATOM   4172  O OH  . TYR B 2 124 ? 81.634  108.658 75.126  1.00 251.61 ? 124 TYR B OH  1 
ATOM   4173  N N   . GLY B 2 125 ? 85.408  112.353 68.248  1.00 306.88 ? 125 GLY B N   1 
ATOM   4174  C CA  . GLY B 2 125 ? 86.323  113.118 67.404  1.00 290.26 ? 125 GLY B CA  1 
ATOM   4175  C C   . GLY B 2 125 ? 87.143  114.149 68.182  1.00 288.27 ? 125 GLY B C   1 
ATOM   4176  O O   . GLY B 2 125 ? 87.228  114.086 69.405  1.00 229.84 ? 125 GLY B O   1 
ATOM   4177  N N   . SER B 2 126 ? 87.758  115.086 67.443  1.00 290.85 ? 126 SER B N   1 
ATOM   4178  C CA  . SER B 2 126 ? 88.127  116.415 67.934  1.00 321.11 ? 126 SER B CA  1 
ATOM   4179  C C   . SER B 2 126 ? 88.934  116.340 69.246  1.00 243.13 ? 126 SER B C   1 
ATOM   4180  O O   . SER B 2 126 ? 89.949  115.662 69.277  1.00 171.72 ? 126 SER B O   1 
ATOM   4181  C CB  . SER B 2 126 ? 86.861  117.287 67.994  1.00 379.89 ? 126 SER B CB  1 
ATOM   4182  O OG  . SER B 2 126 ? 87.148  118.637 68.343  1.00 377.29 ? 126 SER B OG  1 
ATOM   4183  N N   . LEU B 2 127 ? 88.499  117.025 70.322  1.00 266.81 ? 127 LEU B N   1 
ATOM   4184  C CA  . LEU B 2 127 ? 89.221  117.092 71.590  1.00 239.01 ? 127 LEU B CA  1 
ATOM   4185  C C   . LEU B 2 127 ? 89.155  115.773 72.374  1.00 226.12 ? 127 LEU B C   1 
ATOM   4186  O O   . LEU B 2 127 ? 90.215  115.290 72.763  1.00 219.25 ? 127 LEU B O   1 
ATOM   4187  C CB  . LEU B 2 127 ? 88.688  118.292 72.396  1.00 267.66 ? 127 LEU B CB  1 
ATOM   4188  C CG  . LEU B 2 127 ? 89.119  118.403 73.853  1.00 334.64 ? 127 LEU B CG  1 
ATOM   4189  C CD1 . LEU B 2 127 ? 90.613  118.632 73.965  1.00 344.50 ? 127 LEU B CD1 1 
ATOM   4190  C CD2 . LEU B 2 127 ? 88.373  119.545 74.535  1.00 347.19 ? 127 LEU B CD2 1 
ATOM   4191  N N   . PRO B 2 128 ? 87.984  115.150 72.677  1.00 258.15 ? 128 PRO B N   1 
ATOM   4192  C CA  . PRO B 2 128 ? 87.972  113.897 73.445  1.00 296.70 ? 128 PRO B CA  1 
ATOM   4193  C C   . PRO B 2 128 ? 88.827  112.765 72.872  1.00 268.79 ? 128 PRO B C   1 
ATOM   4194  O O   . PRO B 2 128 ? 89.356  111.982 73.654  1.00 331.03 ? 128 PRO B O   1 
ATOM   4195  C CB  . PRO B 2 128 ? 86.483  113.499 73.481  1.00 341.08 ? 128 PRO B CB  1 
ATOM   4196  C CG  . PRO B 2 128 ? 85.758  114.812 73.337  1.00 338.34 ? 128 PRO B CG  1 
ATOM   4197  C CD  . PRO B 2 128 ? 86.612  115.586 72.357  1.00 310.11 ? 128 PRO B CD  1 
ATOM   4198  N N   . ALA B 2 129 ? 88.978  112.680 71.541  1.00 242.04 ? 129 ALA B N   1 
ATOM   4199  C CA  . ALA B 2 129 ? 89.887  111.712 70.933  1.00 263.00 ? 129 ALA B CA  1 
ATOM   4200  C C   . ALA B 2 129 ? 91.350  111.997 71.314  1.00 232.75 ? 129 ALA B C   1 
ATOM   4201  O O   . ALA B 2 129 ? 92.071  111.068 71.691  1.00 227.67 ? 129 ALA B O   1 
ATOM   4202  C CB  . ALA B 2 129 ? 89.669  111.680 69.438  1.00 312.79 ? 129 ALA B CB  1 
ATOM   4203  N N   . PHE B 2 130 ? 91.782  113.268 71.243  1.00 231.02 ? 130 PHE B N   1 
ATOM   4204  C CA  . PHE B 2 130 ? 93.114  113.659 71.692  1.00 203.84 ? 130 PHE B CA  1 
ATOM   4205  C C   . PHE B 2 130 ? 93.294  113.407 73.192  1.00 206.21 ? 130 PHE B C   1 
ATOM   4206  O O   . PHE B 2 130 ? 94.347  112.921 73.592  1.00 284.41 ? 130 PHE B O   1 
ATOM   4207  C CB  . PHE B 2 130 ? 93.385  115.133 71.419  1.00 244.34 ? 130 PHE B CB  1 
ATOM   4208  C CG  . PHE B 2 130 ? 94.737  115.610 71.882  1.00 241.53 ? 130 PHE B CG  1 
ATOM   4209  C CD1 . PHE B 2 130 ? 95.848  115.460 71.064  1.00 237.10 ? 130 PHE B CD1 1 
ATOM   4210  C CD2 . PHE B 2 130 ? 94.902  116.204 73.135  1.00 206.25 ? 130 PHE B CD2 1 
ATOM   4211  C CE1 . PHE B 2 130 ? 97.101  115.904 71.472  1.00 270.08 ? 130 PHE B CE1 1 
ATOM   4212  C CE2 . PHE B 2 130 ? 96.157  116.644 73.543  1.00 222.22 ? 130 PHE B CE2 1 
ATOM   4213  C CZ  . PHE B 2 130 ? 97.253  116.495 72.710  1.00 246.71 ? 130 PHE B CZ  1 
ATOM   4214  N N   . LEU B 2 131 ? 92.292  113.712 74.027  1.00 159.20 ? 131 LEU B N   1 
ATOM   4215  C CA  . LEU B 2 131 ? 92.447  113.462 75.456  1.00 209.76 ? 131 LEU B CA  1 
ATOM   4216  C C   . LEU B 2 131 ? 92.555  111.961 75.793  1.00 225.46 ? 131 LEU B C   1 
ATOM   4217  O O   . LEU B 2 131 ? 93.259  111.611 76.739  1.00 192.09 ? 131 LEU B O   1 
ATOM   4218  C CB  . LEU B 2 131 ? 91.315  114.160 76.212  1.00 247.06 ? 131 LEU B CB  1 
ATOM   4219  C CG  . LEU B 2 131 ? 91.361  115.687 76.212  1.00 299.50 ? 131 LEU B CG  1 
ATOM   4220  C CD1 . LEU B 2 131 ? 90.223  116.209 77.073  1.00 389.27 ? 131 LEU B CD1 1 
ATOM   4221  C CD2 . LEU B 2 131 ? 92.703  116.254 76.687  1.00 228.54 ? 131 LEU B CD2 1 
ATOM   4222  N N   . LYS B 2 132 ? 91.917  111.054 75.041  1.00 227.65 ? 132 LYS B N   1 
ATOM   4223  C CA  . LYS B 2 132 ? 92.171  109.625 75.216  1.00 215.36 ? 132 LYS B CA  1 
ATOM   4224  C C   . LYS B 2 132 ? 93.632  109.292 74.888  1.00 186.88 ? 132 LYS B C   1 
ATOM   4225  O O   . LYS B 2 132 ? 94.298  108.609 75.660  1.00 196.88 ? 132 LYS B O   1 
ATOM   4226  C CB  . LYS B 2 132 ? 91.240  108.763 74.350  1.00 257.90 ? 132 LYS B CB  1 
ATOM   4227  C CG  . LYS B 2 132 ? 90.805  107.446 74.977  1.00 306.92 ? 132 LYS B CG  1 
ATOM   4228  C CD  . LYS B 2 132 ? 91.895  106.480 75.411  1.00 363.37 ? 132 LYS B CD  1 
ATOM   4229  C CE  . LYS B 2 132 ? 91.250  105.261 76.026  1.00 361.59 ? 132 LYS B CE  1 
ATOM   4230  N NZ  . LYS B 2 132 ? 92.193  104.176 76.388  1.00 351.92 ? 132 LYS B NZ  1 
ATOM   4231  N N   . LEU B 2 133 ? 94.138  109.748 73.743  1.00 196.66 ? 133 LEU B N   1 
ATOM   4232  C CA  . LEU B 2 133 ? 95.518  109.486 73.355  1.00 192.96 ? 133 LEU B CA  1 
ATOM   4233  C C   . LEU B 2 133 ? 96.502  110.057 74.381  1.00 167.37 ? 133 LEU B C   1 
ATOM   4234  O O   . LEU B 2 133 ? 97.502  109.420 74.704  1.00 268.14 ? 133 LEU B O   1 
ATOM   4235  C CB  . LEU B 2 133 ? 95.753  110.121 71.985  1.00 242.16 ? 133 LEU B CB  1 
ATOM   4236  C CG  . LEU B 2 133 ? 97.117  109.882 71.359  1.00 245.38 ? 133 LEU B CG  1 
ATOM   4237  C CD1 . LEU B 2 133 ? 97.274  108.409 71.042  1.00 168.27 ? 133 LEU B CD1 1 
ATOM   4238  C CD2 . LEU B 2 133 ? 97.317  110.758 70.125  1.00 335.15 ? 133 LEU B CD2 1 
ATOM   4239  N N   . TRP B 2 134 ? 96.215  111.255 74.883  1.00 159.59 ? 134 TRP B N   1 
ATOM   4240  C CA  . TRP B 2 134 ? 97.050  111.937 75.847  1.00 197.33 ? 134 TRP B CA  1 
ATOM   4241  C C   . TRP B 2 134 ? 97.042  111.206 77.190  1.00 219.05 ? 134 TRP B C   1 
ATOM   4242  O O   . TRP B 2 134 ? 98.112  110.974 77.747  1.00 187.17 ? 134 TRP B O   1 
ATOM   4243  C CB  . TRP B 2 134 ? 96.519  113.360 75.961  1.00 201.66 ? 134 TRP B CB  1 
ATOM   4244  C CG  . TRP B 2 134 ? 97.274  114.307 76.841  1.00 217.10 ? 134 TRP B CG  1 
ATOM   4245  C CD1 . TRP B 2 134 ? 96.835  114.813 78.030  1.00 206.89 ? 134 TRP B CD1 1 
ATOM   4246  C CD2 . TRP B 2 134 ? 98.581  114.872 76.587  1.00 193.46 ? 134 TRP B CD2 1 
ATOM   4247  N NE1 . TRP B 2 134 ? 97.780  115.664 78.539  1.00 199.90 ? 134 TRP B NE1 1 
ATOM   4248  C CE2 . TRP B 2 134 ? 98.865  115.721 77.689  1.00 220.00 ? 134 TRP B CE2 1 
ATOM   4249  C CE3 . TRP B 2 134 ? 99.529  114.736 75.555  1.00 166.92 ? 134 TRP B CE3 1 
ATOM   4250  C CZ2 . TRP B 2 134 ? 100.066 116.443 77.781  1.00 241.30 ? 134 TRP B CZ2 1 
ATOM   4251  C CZ3 . TRP B 2 134 ? 100.715 115.447 75.651  1.00 258.96 ? 134 TRP B CZ3 1 
ATOM   4252  C CH2 . TRP B 2 134 ? 100.976 116.290 76.749  1.00 276.92 ? 134 TRP B CH2 1 
ATOM   4253  N N   . ILE B 2 135 ? 95.862  110.822 77.700  1.00 185.47 ? 135 ILE B N   1 
ATOM   4254  C CA  . ILE B 2 135 ? 95.794  109.994 78.899  1.00 199.52 ? 135 ILE B CA  1 
ATOM   4255  C C   . ILE B 2 135 ? 96.557  108.689 78.674  1.00 188.91 ? 135 ILE B C   1 
ATOM   4256  O O   . ILE B 2 135 ? 97.349  108.292 79.515  1.00 175.67 ? 135 ILE B O   1 
ATOM   4257  C CB  . ILE B 2 135 ? 94.339  109.735 79.346  1.00 211.52 ? 135 ILE B CB  1 
ATOM   4258  C CG1 . ILE B 2 135 ? 93.702  111.002 79.906  1.00 283.58 ? 135 ILE B CG1 1 
ATOM   4259  C CG2 . ILE B 2 135 ? 94.254  108.617 80.383  1.00 251.20 ? 135 ILE B CG2 1 
ATOM   4260  C CD1 . ILE B 2 135 ? 92.205  110.907 80.109  1.00 345.41 ? 135 ILE B CD1 1 
ATOM   4261  N N   . GLU B 2 136 ? 96.329  107.999 77.556  1.00 165.85 ? 136 GLU B N   1 
ATOM   4262  C CA  . GLU B 2 136 ? 96.920  106.678 77.381  1.00 167.57 ? 136 GLU B CA  1 
ATOM   4263  C C   . GLU B 2 136 ? 98.450  106.732 77.264  1.00 156.24 ? 136 GLU B C   1 
ATOM   4264  O O   . GLU B 2 136 ? 99.094  105.780 77.690  1.00 240.66 ? 136 GLU B O   1 
ATOM   4265  C CB  . GLU B 2 136 ? 96.313  105.964 76.180  1.00 177.45 ? 136 GLU B CB  1 
ATOM   4266  C CG  . GLU B 2 136 ? 96.791  104.531 76.040  1.00 215.10 ? 136 GLU B CG  1 
ATOM   4267  C CD  . GLU B 2 136 ? 95.869  103.558 75.321  1.00 313.18 ? 136 GLU B CD  1 
ATOM   4268  O OE1 . GLU B 2 136 ? 94.625  103.817 75.255  1.00 322.90 ? 136 GLU B OE1 1 
ATOM   4269  O OE2 . GLU B 2 136 ? 96.401  102.530 74.825  1.00 417.98 ? 136 GLU B OE2 1 
ATOM   4270  N N   . LEU B 2 137 ? 99.034  107.808 76.715  1.00 157.84 ? 137 LEU B N   1 
ATOM   4271  C CA  . LEU B 2 137 ? 100.480 107.911 76.552  1.00 146.93 ? 137 LEU B CA  1 
ATOM   4272  C C   . LEU B 2 137 ? 101.160 108.562 77.745  1.00 161.53 ? 137 LEU B C   1 
ATOM   4273  O O   . LEU B 2 137 ? 102.333 108.258 77.931  1.00 241.95 ? 137 LEU B O   1 
ATOM   4274  C CB  . LEU B 2 137 ? 100.829 108.695 75.289  1.00 172.71 ? 137 LEU B CB  1 
ATOM   4275  C CG  . LEU B 2 137 ? 100.562 107.937 73.995  1.00 226.83 ? 137 LEU B CG  1 
ATOM   4276  C CD1 . LEU B 2 137 ? 100.848 108.824 72.789  1.00 286.25 ? 137 LEU B CD1 1 
ATOM   4277  C CD2 . LEU B 2 137 ? 101.371 106.637 73.935  1.00 205.28 ? 137 LEU B CD2 1 
ATOM   4278  N N   . LEU B 2 138 ? 100.486 109.407 78.543  1.00 133.50 ? 138 LEU B N   1 
ATOM   4279  C CA  . LEU B 2 138 ? 101.149 109.981 79.714  1.00 184.46 ? 138 LEU B CA  1 
ATOM   4280  C C   . LEU B 2 138 ? 100.747 109.324 81.046  1.00 195.42 ? 138 LEU B C   1 
ATOM   4281  O O   . LEU B 2 138 ? 101.494 109.443 82.022  1.00 189.07 ? 138 LEU B O   1 
ATOM   4282  C CB  . LEU B 2 138 ? 100.875 111.481 79.750  1.00 219.29 ? 138 LEU B CB  1 
ATOM   4283  C CG  . LEU B 2 138 ? 101.897 112.321 78.997  1.00 246.08 ? 138 LEU B CG  1 
ATOM   4284  C CD1 . LEU B 2 138 ? 101.716 112.175 77.494  1.00 264.32 ? 138 LEU B CD1 1 
ATOM   4285  C CD2 . LEU B 2 138 ? 101.787 113.772 79.442  1.00 316.18 ? 138 LEU B CD2 1 
ATOM   4286  N N   . ILE B 2 139 ? 99.600  108.633 81.110  1.00 169.31 ? 139 ILE B N   1 
ATOM   4287  C CA  . ILE B 2 139 ? 99.199  107.931 82.325  1.00 189.52 ? 139 ILE B CA  1 
ATOM   4288  C C   . ILE B 2 139 ? 99.223  106.419 82.123  1.00 166.16 ? 139 ILE B C   1 
ATOM   4289  O O   . ILE B 2 139 ? 100.015 105.737 82.763  1.00 169.66 ? 139 ILE B O   1 
ATOM   4290  C CB  . ILE B 2 139 ? 97.833  108.439 82.825  1.00 176.83 ? 139 ILE B CB  1 
ATOM   4291  C CG1 . ILE B 2 139 ? 97.977  109.876 83.330  1.00 227.04 ? 139 ILE B CG1 1 
ATOM   4292  C CG2 . ILE B 2 139 ? 97.240  107.513 83.878  1.00 190.73 ? 139 ILE B CG2 1 
ATOM   4293  C CD1 . ILE B 2 139 ? 96.684  110.500 83.828  1.00 260.32 ? 139 ILE B CD1 1 
ATOM   4294  N N   . ILE B 2 140 ? 98.361  105.889 81.272  1.00 121.56 ? 140 ILE B N   1 
ATOM   4295  C CA  . ILE B 2 140 ? 98.125  104.461 81.329  1.00 141.07 ? 140 ILE B CA  1 
ATOM   4296  C C   . ILE B 2 140 ? 99.386  103.687 80.891  1.00 134.57 ? 140 ILE B C   1 
ATOM   4297  O O   . ILE B 2 140 ? 99.902  102.924 81.694  1.00 206.30 ? 140 ILE B O   1 
ATOM   4298  C CB  . ILE B 2 140 ? 96.822  104.092 80.579  1.00 169.31 ? 140 ILE B CB  1 
ATOM   4299  C CG1 . ILE B 2 140 ? 95.614  104.769 81.232  1.00 147.39 ? 140 ILE B CG1 1 
ATOM   4300  C CG2 . ILE B 2 140 ? 96.577  102.578 80.468  1.00 173.77 ? 140 ILE B CG2 1 
ATOM   4301  C CD1 . ILE B 2 140 ? 94.392  104.703 80.320  1.00 218.07 ? 140 ILE B CD1 1 
ATOM   4302  N N   . ARG B 2 141 ? 99.885  103.828 79.671  1.00 132.91 ? 141 ARG B N   1 
ATOM   4303  C CA  . ARG B 2 141 ? 100.947 102.951 79.196  1.00 172.31 ? 141 ARG B CA  1 
ATOM   4304  C C   . ARG B 2 141 ? 102.257 103.169 79.966  1.00 153.18 ? 141 ARG B C   1 
ATOM   4305  O O   . ARG B 2 141 ? 103.010 102.217 80.096  1.00 142.83 ? 141 ARG B O   1 
ATOM   4306  C CB  . ARG B 2 141 ? 101.197 103.159 77.694  1.00 271.62 ? 141 ARG B CB  1 
ATOM   4307  C CG  . ARG B 2 141 ? 100.139 102.552 76.790  1.00 276.58 ? 141 ARG B CG  1 
ATOM   4308  C CD  . ARG B 2 141 ? 100.357 102.737 75.288  1.00 239.00 ? 141 ARG B CD  1 
ATOM   4309  N NE  . ARG B 2 141 ? 99.233  102.122 74.582  1.00 315.63 ? 141 ARG B NE  1 
ATOM   4310  C CZ  . ARG B 2 141 ? 99.082  100.818 74.338  1.00 400.47 ? 141 ARG B CZ  1 
ATOM   4311  N NH1 . ARG B 2 141 ? 97.874  100.326 74.085  1.00 460.16 ? 141 ARG B NH1 1 
ATOM   4312  N NH2 . ARG B 2 141 ? 100.124 100.000 74.378  1.00 374.45 ? 141 ARG B NH2 1 
ATOM   4313  N N   . PRO B 2 142 ? 102.632 104.381 80.454  1.00 156.32 ? 142 PRO B N   1 
ATOM   4314  C CA  . PRO B 2 142 ? 103.744 104.535 81.393  1.00 194.99 ? 142 PRO B CA  1 
ATOM   4315  C C   . PRO B 2 142 ? 103.579 103.842 82.741  1.00 188.98 ? 142 PRO B C   1 
ATOM   4316  O O   . PRO B 2 142 ? 104.451 103.071 83.150  1.00 173.67 ? 142 PRO B O   1 
ATOM   4317  C CB  . PRO B 2 142 ? 103.792 106.048 81.623  1.00 182.10 ? 142 PRO B CB  1 
ATOM   4318  C CG  . PRO B 2 142 ? 103.243 106.612 80.388  1.00 198.42 ? 142 PRO B CG  1 
ATOM   4319  C CD  . PRO B 2 142 ? 102.093 105.692 80.089  1.00 154.52 ? 142 PRO B CD  1 
ATOM   4320  N N   . SER B 2 143 ? 102.468 104.099 83.427  1.00 141.64 ? 143 SER B N   1 
ATOM   4321  C CA  . SER B 2 143 ? 102.315 103.582 84.774  1.00 133.54 ? 143 SER B CA  1 
ATOM   4322  C C   . SER B 2 143 ? 102.245 102.051 84.803  1.00 122.14 ? 143 SER B C   1 
ATOM   4323  O O   . SER B 2 143 ? 102.894 101.444 85.650  1.00 156.12 ? 143 SER B O   1 
ATOM   4324  C CB  . SER B 2 143 ? 101.124 104.184 85.441  1.00 154.69 ? 143 SER B CB  1 
ATOM   4325  O OG  . SER B 2 143 ? 99.939  103.904 84.711  1.00 184.06 ? 143 SER B OG  1 
ATOM   4326  N N   . SER B 2 144 ? 101.490 101.405 83.913  1.00 105.40 ? 144 SER B N   1 
ATOM   4327  C CA  . SER B 2 144 ? 101.506 99.951  83.871  1.00 135.74 ? 144 SER B CA  1 
ATOM   4328  C C   . SER B 2 144 ? 102.860 99.355  83.453  1.00 118.64 ? 144 SER B C   1 
ATOM   4329  O O   . SER B 2 144 ? 103.092 98.177  83.725  1.00 147.06 ? 144 SER B O   1 
ATOM   4330  C CB  . SER B 2 144 ? 100.428 99.396  82.973  1.00 176.91 ? 144 SER B CB  1 
ATOM   4331  O OG  . SER B 2 144 ? 100.739 99.592  81.599  1.00 217.43 ? 144 SER B OG  1 
ATOM   4332  N N   . GLN B 2 145 ? 103.744 100.095 82.774  1.00 125.12 ? 145 GLN B N   1 
ATOM   4333  C CA  . GLN B 2 145 ? 105.069 99.565  82.483  1.00 157.78 ? 145 GLN B CA  1 
ATOM   4334  C C   . GLN B 2 145 ? 105.915 99.691  83.729  1.00 135.81 ? 145 GLN B C   1 
ATOM   4335  O O   . GLN B 2 145 ? 106.623 98.754  84.074  1.00 143.27 ? 145 GLN B O   1 
ATOM   4336  C CB  . GLN B 2 145 ? 105.790 100.283 81.346  1.00 180.81 ? 145 GLN B CB  1 
ATOM   4337  C CG  . GLN B 2 145 ? 105.311 99.845  79.980  1.00 203.59 ? 145 GLN B CG  1 
ATOM   4338  C CD  . GLN B 2 145 ? 105.826 100.779 78.911  1.00 257.64 ? 145 GLN B CD  1 
ATOM   4339  O OE1 . GLN B 2 145 ? 107.032 100.987 78.779  1.00 250.42 ? 145 GLN B OE1 1 
ATOM   4340  N NE2 . GLN B 2 145 ? 104.923 101.360 78.132  1.00 332.55 ? 145 GLN B NE2 1 
ATOM   4341  N N   . TYR B 2 146 ? 105.845 100.841 84.395  1.00 126.84 ? 146 TYR B N   1 
ATOM   4342  C CA  . TYR B 2 146 ? 106.673 101.045 85.562  1.00 128.55 ? 146 TYR B CA  1 
ATOM   4343  C C   . TYR B 2 146 ? 106.313 100.011 86.611  1.00 119.95 ? 146 TYR B C   1 
ATOM   4344  O O   . TYR B 2 146 ? 107.249 99.481  87.197  1.00 100.61 ? 146 TYR B O   1 
ATOM   4345  C CB  . TYR B 2 146 ? 106.505 102.484 86.042  1.00 151.52 ? 146 TYR B CB  1 
ATOM   4346  C CG  . TYR B 2 146 ? 107.269 102.678 87.336  1.00 140.88 ? 146 TYR B CG  1 
ATOM   4347  C CD1 . TYR B 2 146 ? 108.659 102.841 87.330  1.00 118.57 ? 146 TYR B CD1 1 
ATOM   4348  C CD2 . TYR B 2 146 ? 106.571 102.656 88.547  1.00 125.37 ? 146 TYR B CD2 1 
ATOM   4349  C CE1 . TYR B 2 146 ? 109.335 103.007 88.524  1.00 143.69 ? 146 TYR B CE1 1 
ATOM   4350  C CE2 . TYR B 2 146 ? 107.243 102.824 89.739  1.00 144.86 ? 146 TYR B CE2 1 
ATOM   4351  C CZ  . TYR B 2 146 ? 108.622 102.993 89.724  1.00 169.23 ? 146 TYR B CZ  1 
ATOM   4352  O OH  . TYR B 2 146 ? 109.218 103.136 90.941  1.00 181.00 ? 146 TYR B OH  1 
ATOM   4353  N N   . ILE B 2 147 ? 105.011 99.750  86.841  1.00 109.11 ? 147 ILE B N   1 
ATOM   4354  C CA  . ILE B 2 147 ? 104.578 98.771  87.826  1.00 110.69 ? 147 ILE B CA  1 
ATOM   4355  C C   . ILE B 2 147 ? 105.137 97.390  87.526  1.00 107.72 ? 147 ILE B C   1 
ATOM   4356  O O   . ILE B 2 147 ? 105.637 96.719  88.447  1.00 121.61 ? 147 ILE B O   1 
ATOM   4357  C CB  . ILE B 2 147 ? 103.059 98.738  87.922  1.00 118.60 ? 147 ILE B CB  1 
ATOM   4358  C CG1 . ILE B 2 147 ? 102.569 99.934  88.735  1.00 113.88 ? 147 ILE B CG1 1 
ATOM   4359  C CG2 . ILE B 2 147 ? 102.523 97.387  88.451  1.00 133.59 ? 147 ILE B CG2 1 
ATOM   4360  C CD1 . ILE B 2 147 ? 101.120 100.174 88.328  1.00 169.87 ? 147 ILE B CD1 1 
ATOM   4361  N N   . VAL B 2 148 ? 105.086 96.967  86.267  1.00 82.37  ? 148 VAL B N   1 
ATOM   4362  C CA  . VAL B 2 148 ? 105.650 95.666  85.986  1.00 106.91 ? 148 VAL B CA  1 
ATOM   4363  C C   . VAL B 2 148 ? 107.196 95.703  86.010  1.00 116.81 ? 148 VAL B C   1 
ATOM   4364  O O   . VAL B 2 148 ? 107.855 94.724  86.350  1.00 133.09 ? 148 VAL B O   1 
ATOM   4365  C CB  . VAL B 2 148 ? 105.051 95.078  84.712  1.00 130.07 ? 148 VAL B CB  1 
ATOM   4366  C CG1 . VAL B 2 148 ? 105.678 93.755  84.323  1.00 136.85 ? 148 VAL B CG1 1 
ATOM   4367  C CG2 . VAL B 2 148 ? 103.564 94.862  84.935  1.00 178.76 ? 148 VAL B CG2 1 
ATOM   4368  N N   . ALA B 2 149 ? 107.821 96.820  85.681  1.00 105.61 ? 149 ALA B N   1 
ATOM   4369  C CA  . ALA B 2 149 ? 109.270 96.931  85.782  1.00 139.15 ? 149 ALA B CA  1 
ATOM   4370  C C   . ALA B 2 149 ? 109.734 96.900  87.218  1.00 112.09 ? 149 ALA B C   1 
ATOM   4371  O O   . ALA B 2 149 ? 110.830 96.444  87.491  1.00 120.29 ? 149 ALA B O   1 
ATOM   4372  C CB  . ALA B 2 149 ? 109.723 98.216  85.142  1.00 217.82 ? 149 ALA B CB  1 
ATOM   4373  N N   . LEU B 2 150 ? 108.911 97.404  88.129  1.00 126.64 ? 150 LEU B N   1 
ATOM   4374  C CA  . LEU B 2 150 ? 109.248 97.440  89.543  1.00 122.40 ? 150 LEU B CA  1 
ATOM   4375  C C   . LEU B 2 150 ? 108.987 96.101  90.212  1.00 114.74 ? 150 LEU B C   1 
ATOM   4376  O O   . LEU B 2 150 ? 109.791 95.731  91.075  1.00 119.20 ? 150 LEU B O   1 
ATOM   4377  C CB  . LEU B 2 150 ? 108.426 98.553  90.195  1.00 106.67 ? 150 LEU B CB  1 
ATOM   4378  C CG  . LEU B 2 150 ? 108.796 98.887  91.624  1.00 122.63 ? 150 LEU B CG  1 
ATOM   4379  C CD1 . LEU B 2 150 ? 110.225 99.379  91.714  1.00 126.29 ? 150 LEU B CD1 1 
ATOM   4380  C CD2 . LEU B 2 150 ? 107.857 99.947  92.179  1.00 158.35 ? 150 LEU B CD2 1 
ATOM   4381  N N   . VAL B 2 151 ? 107.898 95.388  89.854  1.00 96.12  ? 151 VAL B N   1 
ATOM   4382  C CA  . VAL B 2 151 ? 107.750 94.039  90.383  1.00 125.33 ? 151 VAL B CA  1 
ATOM   4383  C C   . VAL B 2 151 ? 108.933 93.175  89.915  1.00 110.94 ? 151 VAL B C   1 
ATOM   4384  O O   . VAL B 2 151 ? 109.469 92.373  90.702  1.00 140.28 ? 151 VAL B O   1 
ATOM   4385  C CB  . VAL B 2 151 ? 106.400 93.360  90.094  1.00 119.97 ? 151 VAL B CB  1 
ATOM   4386  C CG1 . VAL B 2 151 ? 106.252 92.892  88.693  1.00 157.65 ? 151 VAL B CG1 1 
ATOM   4387  C CG2 . VAL B 2 151 ? 106.179 92.114  90.935  1.00 140.00 ? 151 VAL B CG2 1 
ATOM   4388  N N   . PHE B 2 152 ? 109.365 93.337  88.669  1.00 102.09 ? 152 PHE B N   1 
ATOM   4389  C CA  . PHE B 2 152 ? 110.552 92.648  88.220  1.00 129.59 ? 152 PHE B CA  1 
ATOM   4390  C C   . PHE B 2 152 ? 111.702 92.916  89.190  1.00 107.01 ? 152 PHE B C   1 
ATOM   4391  O O   . PHE B 2 152 ? 112.378 91.986  89.622  1.00 113.42 ? 152 PHE B O   1 
ATOM   4392  C CB  . PHE B 2 152 ? 110.933 93.065  86.798  1.00 133.09 ? 152 PHE B CB  1 
ATOM   4393  C CG  . PHE B 2 152 ? 112.310 92.591  86.435  1.00 124.78 ? 152 PHE B CG  1 
ATOM   4394  C CD1 . PHE B 2 152 ? 112.518 91.259  86.154  1.00 118.12 ? 152 PHE B CD1 1 
ATOM   4395  C CD2 . PHE B 2 152 ? 113.391 93.456  86.412  1.00 146.23 ? 152 PHE B CD2 1 
ATOM   4396  C CE1 . PHE B 2 152 ? 113.785 90.800  85.832  1.00 175.70 ? 152 PHE B CE1 1 
ATOM   4397  C CE2 . PHE B 2 152 ? 114.655 93.008  86.090  1.00 136.74 ? 152 PHE B CE2 1 
ATOM   4398  C CZ  . PHE B 2 152 ? 114.849 91.676  85.801  1.00 193.93 ? 152 PHE B CZ  1 
ATOM   4399  N N   . ALA B 2 153 ? 111.920 94.189  89.502  1.00 99.71  ? 153 ALA B N   1 
ATOM   4400  C CA  . ALA B 2 153 ? 113.075 94.582  90.275  1.00 150.31 ? 153 ALA B CA  1 
ATOM   4401  C C   . ALA B 2 153 ? 112.997 93.996  91.696  1.00 144.23 ? 153 ALA B C   1 
ATOM   4402  O O   . ALA B 2 153 ? 113.968 93.443  92.231  1.00 114.52 ? 153 ALA B O   1 
ATOM   4403  C CB  . ALA B 2 153 ? 113.199 96.091  90.215  1.00 165.32 ? 153 ALA B CB  1 
ATOM   4404  N N   . THR B 2 154 ? 111.840 94.079  92.347  1.00 116.49 ? 154 THR B N   1 
ATOM   4405  C CA  . THR B 2 154 ? 111.762 93.573  93.699  1.00 116.16 ? 154 THR B CA  1 
ATOM   4406  C C   . THR B 2 154 ? 111.981 92.084  93.719  1.00 96.72  ? 154 THR B C   1 
ATOM   4407  O O   . THR B 2 154 ? 112.705 91.621  94.595  1.00 125.11 ? 154 THR B O   1 
ATOM   4408  C CB  . THR B 2 154 ? 110.451 93.951  94.392  1.00 131.38 ? 154 THR B CB  1 
ATOM   4409  O OG1 . THR B 2 154 ? 109.372 93.420  93.633  1.00 114.22 ? 154 THR B OG1 1 
ATOM   4410  C CG2 . THR B 2 154 ? 110.350 95.457  94.592  1.00 168.28 ? 154 THR B CG2 1 
ATOM   4411  N N   . TYR B 2 155 ? 111.377 91.345  92.802  1.00 85.12  ? 155 TYR B N   1 
ATOM   4412  C CA  . TYR B 2 155 ? 111.574 89.908  92.836  1.00 106.39 ? 155 TYR B CA  1 
ATOM   4413  C C   . TYR B 2 155 ? 113.002 89.493  92.482  1.00 116.56 ? 155 TYR B C   1 
ATOM   4414  O O   . TYR B 2 155 ? 113.501 88.509  93.042  1.00 142.38 ? 155 TYR B O   1 
ATOM   4415  C CB  . TYR B 2 155 ? 110.720 89.154  91.840  1.00 133.37 ? 155 TYR B CB  1 
ATOM   4416  C CG  . TYR B 2 155 ? 109.356 88.804  92.359  1.00 102.97 ? 155 TYR B CG  1 
ATOM   4417  C CD1 . TYR B 2 155 ? 108.472 89.786  92.710  1.00 120.97 ? 155 TYR B CD1 1 
ATOM   4418  C CD2 . TYR B 2 155 ? 108.957 87.502  92.451  1.00 117.35 ? 155 TYR B CD2 1 
ATOM   4419  C CE1 . TYR B 2 155 ? 107.204 89.489  93.163  1.00 146.52 ? 155 TYR B CE1 1 
ATOM   4420  C CE2 . TYR B 2 155 ? 107.693 87.187  92.907  1.00 152.42 ? 155 TYR B CE2 1 
ATOM   4421  C CZ  . TYR B 2 155 ? 106.805 88.181  93.264  1.00 127.19 ? 155 TYR B CZ  1 
ATOM   4422  O OH  . TYR B 2 155 ? 105.560 87.882  93.722  1.00 146.83 ? 155 TYR B OH  1 
ATOM   4423  N N   . LEU B 2 156 ? 113.657 90.209  91.564  1.00 131.75 ? 156 LEU B N   1 
ATOM   4424  C CA  . LEU B 2 156 ? 115.023 89.867  91.208  1.00 156.49 ? 156 LEU B CA  1 
ATOM   4425  C C   . LEU B 2 156 ? 115.941 90.116  92.402  1.00 156.53 ? 156 LEU B C   1 
ATOM   4426  O O   . LEU B 2 156 ? 116.887 89.352  92.597  1.00 210.61 ? 156 LEU B O   1 
ATOM   4427  C CB  . LEU B 2 156 ? 115.468 90.715  90.027  1.00 173.29 ? 156 LEU B CB  1 
ATOM   4428  C CG  . LEU B 2 156 ? 116.863 90.390  89.520  1.00 214.55 ? 156 LEU B CG  1 
ATOM   4429  C CD1 . LEU B 2 156 ? 116.810 89.094  88.721  1.00 268.25 ? 156 LEU B CD1 1 
ATOM   4430  C CD2 . LEU B 2 156 ? 117.421 91.558  88.717  1.00 287.56 ? 156 LEU B CD2 1 
ATOM   4431  N N   . LEU B 2 157 ? 115.655 91.164  93.187  1.00 100.86 ? 157 LEU B N   1 
ATOM   4432  C CA  . LEU B 2 157 ? 116.452 91.458  94.357  1.00 123.36 ? 157 LEU B CA  1 
ATOM   4433  C C   . LEU B 2 157 ? 116.100 90.660  95.615  1.00 141.51 ? 157 LEU B C   1 
ATOM   4434  O O   . LEU B 2 157 ? 117.021 90.434  96.408  1.00 154.87 ? 157 LEU B O   1 
ATOM   4435  C CB  . LEU B 2 157 ? 116.295 92.948  94.615  1.00 129.26 ? 157 LEU B CB  1 
ATOM   4436  C CG  . LEU B 2 157 ? 117.109 93.814  93.689  1.00 136.25 ? 157 LEU B CG  1 
ATOM   4437  C CD1 . LEU B 2 157 ? 116.748 95.325  93.962  1.00 97.58  ? 157 LEU B CD1 1 
ATOM   4438  C CD2 . LEU B 2 157 ? 118.618 93.383  93.824  1.00 87.93  ? 157 LEU B CD2 1 
ATOM   4439  N N   . LYS B 2 158 ? 114.843 90.250  95.808  1.00 125.41 ? 158 LYS B N   1 
ATOM   4440  C CA  . LYS B 2 158 ? 114.391 89.760  97.106  1.00 115.75 ? 158 LYS B CA  1 
ATOM   4441  C C   . LYS B 2 158 ? 115.267 88.647  97.679  1.00 111.41 ? 158 LYS B C   1 
ATOM   4442  O O   . LYS B 2 158 ? 115.483 88.674  98.867  1.00 183.17 ? 158 LYS B O   1 
ATOM   4443  C CB  . LYS B 2 158 ? 112.946 89.233  97.069  1.00 143.40 ? 158 LYS B CB  1 
ATOM   4444  C CG  . LYS B 2 158 ? 112.236 89.052  98.413  1.00 132.88 ? 158 LYS B CG  1 
ATOM   4445  C CD  . LYS B 2 158 ? 112.065 90.403  99.143  1.00 155.55 ? 158 LYS B CD  1 
ATOM   4446  C CE  . LYS B 2 158 ? 111.126 90.339  100.324 1.00 163.81 ? 158 LYS B CE  1 
ATOM   4447  N NZ  . LYS B 2 158 ? 111.778 89.718  101.488 1.00 168.96 ? 158 LYS B NZ  1 
ATOM   4448  N N   . PRO B 2 159 ? 115.783 87.634  96.970  1.00 111.29 ? 159 PRO B N   1 
ATOM   4449  C CA  . PRO B 2 159 ? 116.668 86.663  97.614  1.00 142.96 ? 159 PRO B CA  1 
ATOM   4450  C C   . PRO B 2 159 ? 117.941 87.231  98.262  1.00 142.52 ? 159 PRO B C   1 
ATOM   4451  O O   . PRO B 2 159 ? 118.533 86.522  99.077  1.00 168.71 ? 159 PRO B O   1 
ATOM   4452  C CB  . PRO B 2 159 ? 117.043 85.720  96.452  1.00 212.78 ? 159 PRO B CB  1 
ATOM   4453  C CG  . PRO B 2 159 ? 115.852 85.859  95.529  1.00 238.95 ? 159 PRO B CG  1 
ATOM   4454  C CD  . PRO B 2 159 ? 115.537 87.338  95.562  1.00 155.35 ? 159 PRO B CD  1 
ATOM   4455  N N   . LEU B 2 160 ? 118.379 88.467  97.935  1.00 110.68 ? 160 LEU B N   1 
ATOM   4456  C CA  . LEU B 2 160 ? 119.485 89.112  98.661  1.00 170.26 ? 160 LEU B CA  1 
ATOM   4457  C C   . LEU B 2 160 ? 119.051 89.771  99.983  1.00 161.53 ? 160 LEU B C   1 
ATOM   4458  O O   . LEU B 2 160 ? 119.913 90.185  100.792 1.00 113.94 ? 160 LEU B O   1 
ATOM   4459  C CB  . LEU B 2 160 ? 120.134 90.180  97.784  1.00 162.07 ? 160 LEU B CB  1 
ATOM   4460  C CG  . LEU B 2 160 ? 121.112 89.693  96.738  1.00 225.57 ? 160 LEU B CG  1 
ATOM   4461  C CD1 . LEU B 2 160 ? 120.450 88.728  95.763  1.00 284.52 ? 160 LEU B CD1 1 
ATOM   4462  C CD2 . LEU B 2 160 ? 121.689 90.913  96.036  1.00 230.06 ? 160 LEU B CD2 1 
ATOM   4463  N N   . PHE B 2 161 ? 117.721 89.878  100.194 1.00 114.92 ? 161 PHE B N   1 
ATOM   4464  C CA  . PHE B 2 161 ? 117.107 90.556  101.321 1.00 105.90 ? 161 PHE B CA  1 
ATOM   4465  C C   . PHE B 2 161 ? 115.904 89.724  101.793 1.00 110.98 ? 161 PHE B C   1 
ATOM   4466  O O   . PHE B 2 161 ? 114.729 90.126  101.614 1.00 104.23 ? 161 PHE B O   1 
ATOM   4467  C CB  . PHE B 2 161 ? 116.748 91.980  100.879 1.00 133.22 ? 161 PHE B CB  1 
ATOM   4468  C CG  . PHE B 2 161 ? 117.944 92.837  100.563 1.00 115.41 ? 161 PHE B CG  1 
ATOM   4469  C CD1 . PHE B 2 161 ? 118.731 93.380  101.545 1.00 156.91 ? 161 PHE B CD1 1 
ATOM   4470  C CD2 . PHE B 2 161 ? 118.289 93.090  99.270  1.00 151.65 ? 161 PHE B CD2 1 
ATOM   4471  C CE1 . PHE B 2 161 ? 119.829 94.165  101.235 1.00 203.50 ? 161 PHE B CE1 1 
ATOM   4472  C CE2 . PHE B 2 161 ? 119.378 93.873  98.957  1.00 183.14 ? 161 PHE B CE2 1 
ATOM   4473  C CZ  . PHE B 2 161 ? 120.153 94.409  99.940  1.00 152.96 ? 161 PHE B CZ  1 
ATOM   4474  N N   . PRO B 2 162 ? 116.168 88.541  102.400 1.00 108.46 ? 162 PRO B N   1 
ATOM   4475  C CA  . PRO B 2 162 ? 115.123 87.539  102.640 1.00 148.39 ? 162 PRO B CA  1 
ATOM   4476  C C   . PRO B 2 162 ? 114.065 87.963  103.657 1.00 156.53 ? 162 PRO B C   1 
ATOM   4477  O O   . PRO B 2 162 ? 112.908 87.598  103.492 1.00 151.76 ? 162 PRO B O   1 
ATOM   4478  C CB  . PRO B 2 162 ? 115.928 86.308  103.096 1.00 198.69 ? 162 PRO B CB  1 
ATOM   4479  C CG  . PRO B 2 162 ? 117.217 86.881  103.674 1.00 186.48 ? 162 PRO B CG  1 
ATOM   4480  C CD  . PRO B 2 162 ? 117.496 88.120  102.859 1.00 119.64 ? 162 PRO B CD  1 
ATOM   4481  N N   . THR B 2 163 ? 114.463 88.733  104.685 1.00 129.13 ? 163 THR B N   1 
ATOM   4482  C CA  . THR B 2 163 ? 113.576 89.125  105.761 1.00 137.13 ? 163 THR B CA  1 
ATOM   4483  C C   . THR B 2 163 ? 113.229 90.609  105.637 1.00 146.69 ? 163 THR B C   1 
ATOM   4484  O O   . THR B 2 163 ? 112.039 90.966  105.606 1.00 170.08 ? 163 THR B O   1 
ATOM   4485  C CB  . THR B 2 163 ? 114.217 88.796  107.113 1.00 196.84 ? 163 THR B CB  1 
ATOM   4486  O OG1 . THR B 2 163 ? 114.563 87.411  107.149 1.00 207.06 ? 163 THR B OG1 1 
ATOM   4487  C CG2 . THR B 2 163 ? 113.299 89.100  108.278 1.00 255.40 ? 163 THR B CG2 1 
ATOM   4488  N N   . CYS B 2 164 ? 114.284 91.437  105.600 1.00 115.16 ? 164 CYS B N   1 
ATOM   4489  C CA  . CYS B 2 164 ? 114.155 92.887  105.680 1.00 134.87 ? 164 CYS B CA  1 
ATOM   4490  C C   . CYS B 2 164 ? 113.790 93.443  104.322 1.00 108.15 ? 164 CYS B C   1 
ATOM   4491  O O   . CYS B 2 164 ? 114.154 92.825  103.342 1.00 145.64 ? 164 CYS B O   1 
ATOM   4492  C CB  . CYS B 2 164 ? 115.420 93.576  106.199 1.00 172.32 ? 164 CYS B CB  1 
ATOM   4493  S SG  . CYS B 2 164 ? 116.948 93.291  105.281 1.00 174.05 ? 164 CYS B SG  1 
ATOM   4494  N N   . PRO B 2 165 ? 113.049 94.571  104.200 1.00 111.76 ? 165 PRO B N   1 
ATOM   4495  C CA  . PRO B 2 165 ? 112.533 94.988  102.914 1.00 167.48 ? 165 PRO B CA  1 
ATOM   4496  C C   . PRO B 2 165 ? 113.676 95.490  102.037 1.00 212.71 ? 165 PRO B C   1 
ATOM   4497  O O   . PRO B 2 165 ? 114.626 96.097  102.546 1.00 176.78 ? 165 PRO B O   1 
ATOM   4498  C CB  . PRO B 2 165 ? 111.515 96.078  103.235 1.00 193.04 ? 165 PRO B CB  1 
ATOM   4499  C CG  . PRO B 2 165 ? 112.041 96.671  104.493 1.00 211.68 ? 165 PRO B CG  1 
ATOM   4500  C CD  . PRO B 2 165 ? 112.612 95.487  105.249 1.00 210.53 ? 165 PRO B CD  1 
ATOM   4501  N N   . VAL B 2 166 ? 113.542 95.203  100.720 1.00 219.07 ? 166 VAL B N   1 
ATOM   4502  C CA  . VAL B 2 166 ? 114.589 95.411  99.730  1.00 134.57 ? 166 VAL B CA  1 
ATOM   4503  C C   . VAL B 2 166 ? 114.696 96.922  99.537  1.00 151.49 ? 166 VAL B C   1 
ATOM   4504  O O   . VAL B 2 166 ? 113.639 97.596  99.469  1.00 107.24 ? 166 VAL B O   1 
ATOM   4505  C CB  . VAL B 2 166 ? 114.203 94.687  98.442  1.00 151.95 ? 166 VAL B CB  1 
ATOM   4506  C CG1 . VAL B 2 166 ? 112.963 95.294  97.766  1.00 187.41 ? 166 VAL B CG1 1 
ATOM   4507  C CG2 . VAL B 2 166 ? 115.328 94.695  97.470  1.00 176.34 ? 166 VAL B CG2 1 
ATOM   4508  N N   . PRO B 2 167 ? 115.937 97.484  99.478  1.00 149.61 ? 167 PRO B N   1 
ATOM   4509  C CA  . PRO B 2 167 ? 116.126 98.952  99.551  1.00 158.23 ? 167 PRO B CA  1 
ATOM   4510  C C   . PRO B 2 167 ? 115.576 99.693  98.338  1.00 120.40 ? 167 PRO B C   1 
ATOM   4511  O O   . PRO B 2 167 ? 115.955 99.350  97.224  1.00 177.42 ? 167 PRO B O   1 
ATOM   4512  C CB  . PRO B 2 167 ? 117.645 99.146  99.653  1.00 151.29 ? 167 PRO B CB  1 
ATOM   4513  C CG  . PRO B 2 167 ? 118.237 97.824  99.170  1.00 133.05 ? 167 PRO B CG  1 
ATOM   4514  C CD  . PRO B 2 167 ? 117.206 96.734  99.417  1.00 101.96 ? 167 PRO B CD  1 
ATOM   4515  N N   . GLU B 2 168 ? 114.676 100.665 98.552  1.00 158.87 ? 168 GLU B N   1 
ATOM   4516  C CA  . GLU B 2 168 ? 113.891 101.261 97.466  1.00 211.33 ? 168 GLU B CA  1 
ATOM   4517  C C   . GLU B 2 168 ? 114.782 101.956 96.430  1.00 186.69 ? 168 GLU B C   1 
ATOM   4518  O O   . GLU B 2 168 ? 114.538 101.868 95.206  1.00 123.55 ? 168 GLU B O   1 
ATOM   4519  C CB  . GLU B 2 168 ? 112.820 102.224 98.006  1.00 242.39 ? 168 GLU B CB  1 
ATOM   4520  C CG  . GLU B 2 168 ? 111.710 101.529 98.800  1.00 332.37 ? 168 GLU B CG  1 
ATOM   4521  C CD  . GLU B 2 168 ? 110.877 100.445 98.115  1.00 377.63 ? 168 GLU B CD  1 
ATOM   4522  O OE1 . GLU B 2 168 ? 110.971 100.278 96.882  1.00 389.18 ? 168 GLU B OE1 1 
ATOM   4523  O OE2 . GLU B 2 168 ? 110.122 99.752  98.827  1.00 394.69 ? 168 GLU B OE2 1 
ATOM   4524  N N   . GLU B 2 169 ? 115.824 102.628 96.917  1.00 179.83 ? 169 GLU B N   1 
ATOM   4525  C CA  . GLU B 2 169 ? 116.797 103.236 96.022  1.00 199.28 ? 169 GLU B CA  1 
ATOM   4526  C C   . GLU B 2 169 ? 117.408 102.228 95.034  1.00 120.91 ? 169 GLU B C   1 
ATOM   4527  O O   . GLU B 2 169 ? 117.858 102.674 94.003  1.00 169.01 ? 169 GLU B O   1 
ATOM   4528  C CB  . GLU B 2 169 ? 117.884 103.957 96.832  1.00 271.03 ? 169 GLU B CB  1 
ATOM   4529  C CG  . GLU B 2 169 ? 118.580 103.114 97.900  1.00 299.61 ? 169 GLU B CG  1 
ATOM   4530  C CD  . GLU B 2 169 ? 118.080 103.293 99.326  1.00 339.08 ? 169 GLU B CD  1 
ATOM   4531  O OE1 . GLU B 2 169 ? 116.849 103.381 99.509  1.00 312.80 ? 169 GLU B OE1 1 
ATOM   4532  O OE2 . GLU B 2 169 ? 118.923 103.332 100.252 1.00 388.77 ? 169 GLU B OE2 1 
ATOM   4533  N N   . ALA B 2 170 ? 117.483 100.922 95.342  1.00 134.09 ? 170 ALA B N   1 
ATOM   4534  C CA  . ALA B 2 170 ? 118.038 99.895  94.455  1.00 133.29 ? 170 ALA B CA  1 
ATOM   4535  C C   . ALA B 2 170 ? 116.929 99.292  93.629  1.00 118.77 ? 170 ALA B C   1 
ATOM   4536  O O   . ALA B 2 170 ? 117.132 99.028  92.465  1.00 141.15 ? 170 ALA B O   1 
ATOM   4537  C CB  . ALA B 2 170 ? 118.787 98.780  95.171  1.00 117.15 ? 170 ALA B CB  1 
ATOM   4538  N N   . ALA B 2 171 ? 115.765 99.087  94.208  1.00 133.85 ? 171 ALA B N   1 
ATOM   4539  C CA  . ALA B 2 171 ? 114.641 98.597  93.444  1.00 155.85 ? 171 ALA B CA  1 
ATOM   4540  C C   . ALA B 2 171 ? 114.363 99.543  92.286  1.00 134.80 ? 171 ALA B C   1 
ATOM   4541  O O   . ALA B 2 171 ? 114.094 99.070  91.177  1.00 180.47 ? 171 ALA B O   1 
ATOM   4542  C CB  . ALA B 2 171 ? 113.438 98.467  94.351  1.00 224.43 ? 171 ALA B CB  1 
ATOM   4543  N N   . LYS B 2 172 ? 114.425 100.864 92.507  1.00 87.33  ? 172 LYS B N   1 
ATOM   4544  C CA  . LYS B 2 172 ? 114.093 101.748 91.402  1.00 125.64 ? 172 LYS B CA  1 
ATOM   4545  C C   . LYS B 2 172 ? 115.179 101.784 90.314  1.00 127.20 ? 172 LYS B C   1 
ATOM   4546  O O   . LYS B 2 172 ? 114.855 101.891 89.131  1.00 94.35  ? 172 LYS B O   1 
ATOM   4547  C CB  . LYS B 2 172 ? 113.797 103.135 91.939  1.00 158.83 ? 172 LYS B CB  1 
ATOM   4548  C CG  . LYS B 2 172 ? 112.450 103.239 92.608  1.00 119.83 ? 172 LYS B CG  1 
ATOM   4549  C CD  . LYS B 2 172 ? 112.292 104.655 93.129  1.00 191.95 ? 172 LYS B CD  1 
ATOM   4550  C CE  . LYS B 2 172 ? 110.935 104.849 93.753  1.00 241.91 ? 172 LYS B CE  1 
ATOM   4551  N NZ  . LYS B 2 172 ? 110.717 106.260 94.132  1.00 293.63 ? 172 LYS B NZ  1 
ATOM   4552  N N   . LEU B 2 173 ? 116.460 101.681 90.660  1.00 112.48 ? 173 LEU B N   1 
ATOM   4553  C CA  . LEU B 2 173 ? 117.486 101.567 89.631  1.00 123.70 ? 173 LEU B CA  1 
ATOM   4554  C C   . LEU B 2 173 ? 117.328 100.280 88.844  1.00 109.80 ? 173 LEU B C   1 
ATOM   4555  O O   . LEU B 2 173 ? 117.428 100.331 87.610  1.00 165.43 ? 173 LEU B O   1 
ATOM   4556  C CB  . LEU B 2 173 ? 118.913 101.562 90.166  1.00 115.73 ? 173 LEU B CB  1 
ATOM   4557  C CG  . LEU B 2 173 ? 119.350 102.880 90.823  1.00 174.08 ? 173 LEU B CG  1 
ATOM   4558  C CD1 . LEU B 2 173 ? 120.906 102.864 90.903  1.00 139.39 ? 173 LEU B CD1 1 
ATOM   4559  C CD2 . LEU B 2 173 ? 118.702 104.204 90.201  1.00 143.06 ? 173 LEU B CD2 1 
ATOM   4560  N N   . VAL B 2 174 ? 117.118 99.152  89.510  1.00 80.87  ? 174 VAL B N   1 
ATOM   4561  C CA  . VAL B 2 174 ? 116.973 97.937  88.747  1.00 103.75 ? 174 VAL B CA  1 
ATOM   4562  C C   . VAL B 2 174 ? 115.694 97.934  87.923  1.00 95.02  ? 174 VAL B C   1 
ATOM   4563  O O   . VAL B 2 174 ? 115.693 97.293  86.875  1.00 148.47 ? 174 VAL B O   1 
ATOM   4564  C CB  . VAL B 2 174 ? 117.144 96.704  89.610  1.00 123.78 ? 174 VAL B CB  1 
ATOM   4565  C CG1 . VAL B 2 174 ? 116.731 95.421  88.871  1.00 140.61 ? 174 VAL B CG1 1 
ATOM   4566  C CG2 . VAL B 2 174 ? 118.609 96.672  90.050  1.00 143.59 ? 174 VAL B CG2 1 
ATOM   4567  N N   . ALA B 2 175 ? 114.646 98.638  88.327  1.00 114.24 ? 175 ALA B N   1 
ATOM   4568  C CA  . ALA B 2 175 ? 113.477 98.792  87.462  1.00 143.64 ? 175 ALA B CA  1 
ATOM   4569  C C   . ALA B 2 175 ? 113.868 99.516  86.187  1.00 116.34 ? 175 ALA B C   1 
ATOM   4570  O O   . ALA B 2 175 ? 113.506 99.111  85.085  1.00 134.07 ? 175 ALA B O   1 
ATOM   4571  C CB  . ALA B 2 175 ? 112.324 99.505  88.144  1.00 171.22 ? 175 ALA B CB  1 
ATOM   4572  N N   . CYS B 2 176 ? 114.618 100.603 86.341  1.00 120.96 ? 176 CYS B N   1 
ATOM   4573  C CA  . CYS B 2 176 ? 115.017 101.405 85.197  1.00 127.69 ? 176 CYS B CA  1 
ATOM   4574  C C   . CYS B 2 176 ? 116.000 100.668 84.287  1.00 99.98  ? 176 CYS B C   1 
ATOM   4575  O O   . CYS B 2 176 ? 115.862 100.770 83.087  1.00 116.07 ? 176 CYS B O   1 
ATOM   4576  C CB  . CYS B 2 176 ? 115.499 102.734 85.731  1.00 141.93 ? 176 CYS B CB  1 
ATOM   4577  S SG  . CYS B 2 176 ? 114.092 103.514 86.570  1.00 217.73 ? 176 CYS B SG  1 
ATOM   4578  N N   . LEU B 2 177 ? 116.954 99.935  84.833  1.00 99.61  ? 177 LEU B N   1 
ATOM   4579  C CA  . LEU B 2 177 ? 117.847 99.135  84.012  1.00 140.21 ? 177 LEU B CA  1 
ATOM   4580  C C   . LEU B 2 177 ? 117.078 98.161  83.126  1.00 132.35 ? 177 LEU B C   1 
ATOM   4581  O O   . LEU B 2 177 ? 117.520 97.933  81.994  1.00 277.71 ? 177 LEU B O   1 
ATOM   4582  C CB  . LEU B 2 177 ? 118.868 98.393  84.887  1.00 160.11 ? 177 LEU B CB  1 
ATOM   4583  C CG  . LEU B 2 177 ? 119.935 99.337  85.464  1.00 180.19 ? 177 LEU B CG  1 
ATOM   4584  C CD1 . LEU B 2 177 ? 120.615 98.794  86.699  1.00 224.09 ? 177 LEU B CD1 1 
ATOM   4585  C CD2 . LEU B 2 177 ? 121.009 99.635  84.445  1.00 165.15 ? 177 LEU B CD2 1 
ATOM   4586  N N   . CYS B 2 178 ? 115.964 97.611  83.604  1.00 102.54 ? 178 CYS B N   1 
ATOM   4587  C CA  . CYS B 2 178 ? 115.136 96.719  82.816  1.00 137.74 ? 178 CYS B CA  1 
ATOM   4588  C C   . CYS B 2 178 ? 114.446 97.474  81.674  1.00 132.96 ? 178 CYS B C   1 
ATOM   4589  O O   . CYS B 2 178 ? 114.535 97.044  80.519  1.00 174.58 ? 178 CYS B O   1 
ATOM   4590  C CB  . CYS B 2 178 ? 114.128 96.040  83.730  1.00 203.13 ? 178 CYS B CB  1 
ATOM   4591  S SG  . CYS B 2 178 ? 113.077 94.809  82.925  1.00 206.35 ? 178 CYS B SG  1 
ATOM   4592  N N   . VAL B 2 179 ? 113.787 98.594  81.970  1.00 101.45 ? 179 VAL B N   1 
ATOM   4593  C CA  . VAL B 2 179 ? 113.098 99.353  80.924  1.00 130.89 ? 179 VAL B CA  1 
ATOM   4594  C C   . VAL B 2 179 ? 114.064 99.905  79.859  1.00 135.55 ? 179 VAL B C   1 
ATOM   4595  O O   . VAL B 2 179 ? 113.731 99.910  78.685  1.00 138.79 ? 179 VAL B O   1 
ATOM   4596  C CB  . VAL B 2 179 ? 112.247 100.473 81.556  1.00 148.62 ? 179 VAL B CB  1 
ATOM   4597  C CG1 . VAL B 2 179 ? 111.658 101.486 80.600  1.00 122.36 ? 179 VAL B CG1 1 
ATOM   4598  C CG2 . VAL B 2 179 ? 111.115 99.861  82.340  1.00 215.33 ? 179 VAL B CG2 1 
ATOM   4599  N N   . LEU B 2 180 ? 115.251 100.376 80.234  1.00 127.43 ? 180 LEU B N   1 
ATOM   4600  C CA  . LEU B 2 180 ? 116.215 100.847 79.252  1.00 99.85  ? 180 LEU B CA  1 
ATOM   4601  C C   . LEU B 2 180 ? 116.749 99.712  78.408  1.00 97.94  ? 180 LEU B C   1 
ATOM   4602  O O   . LEU B 2 180 ? 116.777 99.861  77.193  1.00 139.10 ? 180 LEU B O   1 
ATOM   4603  C CB  . LEU B 2 180 ? 117.457 101.453 79.909  1.00 118.69 ? 180 LEU B CB  1 
ATOM   4604  C CG  . LEU B 2 180 ? 117.251 102.749 80.686  1.00 159.81 ? 180 LEU B CG  1 
ATOM   4605  C CD1 . LEU B 2 180 ? 118.635 103.441 80.898  1.00 164.58 ? 180 LEU B CD1 1 
ATOM   4606  C CD2 . LEU B 2 180 ? 116.126 103.628 80.028  1.00 102.42 ? 180 LEU B CD2 1 
ATOM   4607  N N   . LEU B 2 181 ? 117.192 98.619  79.034  1.00 104.32 ? 181 LEU B N   1 
ATOM   4608  C CA  . LEU B 2 181 ? 117.703 97.496  78.262  1.00 116.94 ? 181 LEU B CA  1 
ATOM   4609  C C   . LEU B 2 181 ? 116.668 96.994  77.235  1.00 138.89 ? 181 LEU B C   1 
ATOM   4610  O O   . LEU B 2 181 ? 117.027 96.748  76.063  1.00 236.91 ? 181 LEU B O   1 
ATOM   4611  C CB  . LEU B 2 181 ? 118.097 96.327  79.156  1.00 145.65 ? 181 LEU B CB  1 
ATOM   4612  C CG  . LEU B 2 181 ? 118.629 95.106  78.389  1.00 162.80 ? 181 LEU B CG  1 
ATOM   4613  C CD1 . LEU B 2 181 ? 119.962 95.452  77.770  1.00 261.39 ? 181 LEU B CD1 1 
ATOM   4614  C CD2 . LEU B 2 181 ? 118.796 93.863  79.240  1.00 236.58 ? 181 LEU B CD2 1 
ATOM   4615  N N   . LEU B 2 182 ? 115.405 96.862  77.632  1.00 112.50 ? 182 LEU B N   1 
ATOM   4616  C CA  . LEU B 2 182 ? 114.399 96.408  76.693  1.00 161.00 ? 182 LEU B CA  1 
ATOM   4617  C C   . LEU B 2 182 ? 113.984 97.487  75.681  1.00 161.42 ? 182 LEU B C   1 
ATOM   4618  O O   . LEU B 2 182 ? 113.441 97.148  74.620  1.00 230.04 ? 182 LEU B O   1 
ATOM   4619  C CB  . LEU B 2 182 ? 113.221 95.893  77.521  1.00 171.72 ? 182 LEU B CB  1 
ATOM   4620  C CG  . LEU B 2 182 ? 113.506 94.535  78.139  1.00 180.22 ? 182 LEU B CG  1 
ATOM   4621  C CD1 . LEU B 2 182 ? 112.354 94.131  79.037  1.00 254.26 ? 182 LEU B CD1 1 
ATOM   4622  C CD2 . LEU B 2 182 ? 113.754 93.477  77.075  1.00 168.71 ? 182 LEU B CD2 1 
ATOM   4623  N N   . THR B 2 183 ? 114.218 98.767  75.981  1.00 113.30 ? 183 THR B N   1 
ATOM   4624  C CA  . THR B 2 183 ? 114.022 99.800  74.987  1.00 138.14 ? 183 THR B CA  1 
ATOM   4625  C C   . THR B 2 183 ? 115.114 99.665  73.934  1.00 136.87 ? 183 THR B C   1 
ATOM   4626  O O   . THR B 2 183 ? 114.827 99.777  72.749  1.00 197.94 ? 183 THR B O   1 
ATOM   4627  C CB  . THR B 2 183 ? 114.002 101.202 75.609  1.00 173.12 ? 183 THR B CB  1 
ATOM   4628  O OG1 . THR B 2 183 ? 112.912 101.344 76.517  1.00 126.45 ? 183 THR B OG1 1 
ATOM   4629  C CG2 . THR B 2 183 ? 113.849 102.310 74.586  1.00 216.57 ? 183 THR B CG2 1 
ATOM   4630  N N   . ALA B 2 184 ? 116.361 99.456  74.356  1.00 158.72 ? 184 ALA B N   1 
ATOM   4631  C CA  . ALA B 2 184 ? 117.462 99.297  73.410  1.00 163.64 ? 184 ALA B CA  1 
ATOM   4632  C C   . ALA B 2 184 ? 117.222 98.075  72.517  1.00 141.62 ? 184 ALA B C   1 
ATOM   4633  O O   . ALA B 2 184 ? 117.435 98.185  71.292  1.00 284.84 ? 184 ALA B O   1 
ATOM   4634  C CB  . ALA B 2 184 ? 118.803 99.213  74.111  1.00 161.85 ? 184 ALA B CB  1 
ATOM   4635  N N   . VAL B 2 185 ? 116.785 96.942  73.087  1.00 108.09 ? 185 VAL B N   1 
ATOM   4636  C CA  . VAL B 2 185 ? 116.570 95.741  72.291  1.00 149.13 ? 185 VAL B CA  1 
ATOM   4637  C C   . VAL B 2 185 ? 115.448 95.942  71.265  1.00 147.10 ? 185 VAL B C   1 
ATOM   4638  O O   . VAL B 2 185 ? 115.621 95.520  70.115  1.00 247.65 ? 185 VAL B O   1 
ATOM   4639  C CB  . VAL B 2 185 ? 116.394 94.503  73.176  1.00 212.42 ? 185 VAL B CB  1 
ATOM   4640  C CG1 . VAL B 2 185 ? 115.731 93.320  72.462  1.00 216.06 ? 185 VAL B CG1 1 
ATOM   4641  C CG2 . VAL B 2 185 ? 117.767 94.128  73.734  1.00 212.41 ? 185 VAL B CG2 1 
ATOM   4642  N N   . ASN B 2 186 ? 114.367 96.616  71.630  1.00 144.97 ? 186 ASN B N   1 
ATOM   4643  C CA  . ASN B 2 186 ? 113.309 96.925  70.668  1.00 187.47 ? 186 ASN B CA  1 
ATOM   4644  C C   . ASN B 2 186 ? 113.748 97.940  69.604  1.00 178.57 ? 186 ASN B C   1 
ATOM   4645  O O   . ASN B 2 186 ? 113.189 97.897  68.504  1.00 211.63 ? 186 ASN B O   1 
ATOM   4646  C CB  . ASN B 2 186 ? 112.009 97.353  71.364  1.00 198.58 ? 186 ASN B CB  1 
ATOM   4647  C CG  . ASN B 2 186 ? 111.252 96.147  71.865  1.00 250.33 ? 186 ASN B CG  1 
ATOM   4648  O OD1 . ASN B 2 186 ? 110.413 95.622  71.141  1.00 170.24 ? 186 ASN B OD1 1 
ATOM   4649  N ND2 . ASN B 2 186 ? 111.557 95.684  73.069  1.00 315.32 ? 186 ASN B ND2 1 
ATOM   4650  N N   . CYS B 2 187 ? 114.710 98.837  69.907  1.00 156.46 ? 187 CYS B N   1 
ATOM   4651  C CA  . CYS B 2 187 ? 115.255 99.758  68.910  1.00 187.09 ? 187 CYS B CA  1 
ATOM   4652  C C   . CYS B 2 187 ? 116.213 99.050  67.956  1.00 173.77 ? 187 CYS B C   1 
ATOM   4653  O O   . CYS B 2 187 ? 116.205 99.346  66.771  1.00 194.82 ? 187 CYS B O   1 
ATOM   4654  C CB  . CYS B 2 187 ? 115.938 100.949 69.566  1.00 231.04 ? 187 CYS B CB  1 
ATOM   4655  S SG  . CYS B 2 187 ? 114.756 102.054 70.386  1.00 290.84 ? 187 CYS B SG  1 
ATOM   4656  N N   . TYR B 2 188 ? 117.039 98.129  68.450  1.00 181.22 ? 188 TYR B N   1 
ATOM   4657  C CA  . TYR B 2 188 ? 118.016 97.444  67.619  1.00 181.83 ? 188 TYR B CA  1 
ATOM   4658  C C   . TYR B 2 188 ? 117.376 96.435  66.684  1.00 168.98 ? 188 TYR B C   1 
ATOM   4659  O O   . TYR B 2 188 ? 117.875 96.324  65.556  1.00 292.08 ? 188 TYR B O   1 
ATOM   4660  C CB  . TYR B 2 188 ? 119.105 96.744  68.449  1.00 221.24 ? 188 TYR B CB  1 
ATOM   4661  C CG  . TYR B 2 188 ? 120.312 97.651  68.708  1.00 287.79 ? 188 TYR B CG  1 
ATOM   4662  C CD1 . TYR B 2 188 ? 120.197 99.053  68.875  1.00 249.22 ? 188 TYR B CD1 1 
ATOM   4663  C CD2 . TYR B 2 188 ? 121.602 97.092  68.746  1.00 272.31 ? 188 TYR B CD2 1 
ATOM   4664  C CE1 . TYR B 2 188 ? 121.314 99.858  69.077  1.00 219.89 ? 188 TYR B CE1 1 
ATOM   4665  C CE2 . TYR B 2 188 ? 122.719 97.891  68.954  1.00 301.60 ? 188 TYR B CE2 1 
ATOM   4666  C CZ  . TYR B 2 188 ? 122.576 99.268  69.119  1.00 286.05 ? 188 TYR B CZ  1 
ATOM   4667  O OH  . TYR B 2 188 ? 123.705 100.011 69.322  1.00 244.56 ? 188 TYR B OH  1 
ATOM   4668  N N   . SER B 2 189 ? 116.326 95.720  67.109  1.00 154.37 ? 189 SER B N   1 
ATOM   4669  C CA  . SER B 2 189 ? 115.844 94.637  66.258  1.00 230.56 ? 189 SER B CA  1 
ATOM   4670  C C   . SER B 2 189 ? 114.460 94.101  66.608  1.00 213.24 ? 189 SER B C   1 
ATOM   4671  O O   . SER B 2 189 ? 114.326 93.414  67.628  1.00 303.45 ? 189 SER B O   1 
ATOM   4672  C CB  . SER B 2 189 ? 116.837 93.484  66.278  1.00 236.76 ? 189 SER B CB  1 
ATOM   4673  O OG  . SER B 2 189 ? 116.403 92.467  65.386  1.00 241.46 ? 189 SER B OG  1 
ATOM   4674  N N   . VAL B 2 190 ? 113.457 94.350  65.737  1.00 188.06 ? 190 VAL B N   1 
ATOM   4675  C CA  . VAL B 2 190 ? 112.182 93.624  65.828  1.00 263.80 ? 190 VAL B CA  1 
ATOM   4676  C C   . VAL B 2 190 ? 112.387 92.102  65.645  1.00 241.61 ? 190 VAL B C   1 
ATOM   4677  O O   . VAL B 2 190 ? 111.663 91.304  66.260  1.00 192.48 ? 190 VAL B O   1 
ATOM   4678  C CB  . VAL B 2 190 ? 111.095 94.209  64.890  1.00 275.27 ? 190 VAL B CB  1 
ATOM   4679  C CG1 . VAL B 2 190 ? 109.904 93.276  64.670  1.00 287.54 ? 190 VAL B CG1 1 
ATOM   4680  C CG2 . VAL B 2 190 ? 110.574 95.539  65.412  1.00 282.04 ? 190 VAL B CG2 1 
ATOM   4681  N N   . LYS B 2 191 ? 113.378 91.698  64.832  1.00 286.95 ? 191 LYS B N   1 
ATOM   4682  C CA  . LYS B 2 191 ? 113.712 90.293  64.625  1.00 348.52 ? 191 LYS B CA  1 
ATOM   4683  C C   . LYS B 2 191 ? 114.227 89.625  65.913  1.00 318.61 ? 191 LYS B C   1 
ATOM   4684  O O   . LYS B 2 191 ? 114.055 88.410  66.060  1.00 352.96 ? 191 LYS B O   1 
ATOM   4685  C CB  . LYS B 2 191 ? 114.718 90.165  63.471  1.00 415.49 ? 191 LYS B CB  1 
ATOM   4686  C CG  . LYS B 2 191 ? 114.929 88.743  62.961  1.00 443.96 ? 191 LYS B CG  1 
ATOM   4687  C CD  . LYS B 2 191 ? 115.765 88.651  61.704  1.00 439.46 ? 191 LYS B CD  1 
ATOM   4688  C CE  . LYS B 2 191 ? 115.961 87.227  61.222  1.00 393.43 ? 191 LYS B CE  1 
ATOM   4689  N NZ  . LYS B 2 191 ? 116.901 86.459  62.076  1.00 345.62 ? 191 LYS B NZ  1 
ATOM   4690  N N   . ALA B 2 192 ? 114.847 90.390  66.837  1.00 251.83 ? 192 ALA B N   1 
ATOM   4691  C CA  . ALA B 2 192 ? 115.239 89.895  68.155  1.00 265.51 ? 192 ALA B CA  1 
ATOM   4692  C C   . ALA B 2 192 ? 114.101 90.030  69.171  1.00 227.83 ? 192 ALA B C   1 
ATOM   4693  O O   . ALA B 2 192 ? 113.794 89.067  69.861  1.00 165.65 ? 192 ALA B O   1 
ATOM   4694  C CB  . ALA B 2 192 ? 116.478 90.612  68.640  1.00 275.70 ? 192 ALA B CB  1 
ATOM   4695  N N   . ALA B 2 193 ? 113.475 91.208  69.277  1.00 254.93 ? 193 ALA B N   1 
ATOM   4696  C CA  . ALA B 2 193 ? 112.479 91.477  70.317  1.00 228.79 ? 193 ALA B CA  1 
ATOM   4697  C C   . ALA B 2 193 ? 111.197 90.630  70.184  1.00 180.23 ? 193 ALA B C   1 
ATOM   4698  O O   . ALA B 2 193 ? 110.570 90.337  71.208  1.00 222.17 ? 193 ALA B O   1 
ATOM   4699  C CB  . ALA B 2 193 ? 112.179 92.950  70.354  1.00 173.53 ? 193 ALA B CB  1 
ATOM   4700  N N   . THR B 2 194 ? 110.832 90.209  68.968  1.00 178.71 ? 194 THR B N   1 
ATOM   4701  C CA  . THR B 2 194 ? 109.838 89.157  68.777  1.00 217.21 ? 194 THR B CA  1 
ATOM   4702  C C   . THR B 2 194 ? 110.230 87.825  69.447  1.00 207.93 ? 194 THR B C   1 
ATOM   4703  O O   . THR B 2 194 ? 109.383 87.230  70.112  1.00 259.77 ? 194 THR B O   1 
ATOM   4704  C CB  . THR B 2 194 ? 109.533 88.928  67.288  1.00 295.00 ? 194 THR B CB  1 
ATOM   4705  O OG1 . THR B 2 194 ? 110.735 88.823  66.520  1.00 316.40 ? 194 THR B OG1 1 
ATOM   4706  C CG2 . THR B 2 194 ? 108.690 90.037  66.698  1.00 288.81 ? 194 THR B CG2 1 
ATOM   4707  N N   . ARG B 2 195 ? 111.481 87.349  69.294  1.00 209.61 ? 195 ARG B N   1 
ATOM   4708  C CA  . ARG B 2 195 ? 111.937 86.091  69.896  1.00 283.33 ? 195 ARG B CA  1 
ATOM   4709  C C   . ARG B 2 195 ? 111.948 86.174  71.435  1.00 271.27 ? 195 ARG B C   1 
ATOM   4710  O O   . ARG B 2 195 ? 111.653 85.199  72.121  1.00 206.79 ? 195 ARG B O   1 
ATOM   4711  C CB  . ARG B 2 195 ? 113.331 85.693  69.383  1.00 326.52 ? 195 ARG B CB  1 
ATOM   4712  C CG  . ARG B 2 195 ? 113.436 85.435  67.888  1.00 342.44 ? 195 ARG B CG  1 
ATOM   4713  C CD  . ARG B 2 195 ? 114.833 84.963  67.514  1.00 342.47 ? 195 ARG B CD  1 
ATOM   4714  N NE  . ARG B 2 195 ? 115.001 83.522  67.743  1.00 361.43 ? 195 ARG B NE  1 
ATOM   4715  C CZ  . ARG B 2 195 ? 116.138 82.835  67.613  1.00 323.53 ? 195 ARG B CZ  1 
ATOM   4716  N NH1 . ARG B 2 195 ? 116.122 81.507  67.670  1.00 234.50 ? 195 ARG B NH1 1 
ATOM   4717  N NH2 . ARG B 2 195 ? 117.284 83.472  67.416  1.00 302.75 ? 195 ARG B NH2 1 
ATOM   4718  N N   . VAL B 2 196 ? 112.281 87.354  71.981  1.00 252.12 ? 196 VAL B N   1 
ATOM   4719  C CA  . VAL B 2 196 ? 112.227 87.632  73.414  1.00 201.45 ? 196 VAL B CA  1 
ATOM   4720  C C   . VAL B 2 196 ? 110.778 87.607  73.918  1.00 209.93 ? 196 VAL B C   1 
ATOM   4721  O O   . VAL B 2 196 ? 110.563 87.278  75.078  1.00 249.41 ? 196 VAL B O   1 
ATOM   4722  C CB  . VAL B 2 196 ? 112.958 88.963  73.732  1.00 213.22 ? 196 VAL B CB  1 
ATOM   4723  C CG1 . VAL B 2 196 ? 112.839 89.420  75.180  1.00 196.19 ? 196 VAL B CG1 1 
ATOM   4724  C CG2 . VAL B 2 196 ? 114.448 88.888  73.362  1.00 225.96 ? 196 VAL B CG2 1 
ATOM   4725  N N   . GLN B 2 197 ? 109.778 87.945  73.082  1.00 288.04 ? 197 GLN B N   1 
ATOM   4726  C CA  . GLN B 2 197 ? 108.370 87.815  73.460  1.00 297.33 ? 197 GLN B CA  1 
ATOM   4727  C C   . GLN B 2 197 ? 107.878 86.368  73.320  1.00 238.30 ? 197 GLN B C   1 
ATOM   4728  O O   . GLN B 2 197 ? 107.114 85.901  74.161  1.00 245.20 ? 197 GLN B O   1 
ATOM   4729  C CB  . GLN B 2 197 ? 107.498 88.771  72.634  1.00 299.39 ? 197 GLN B CB  1 
ATOM   4730  C CG  . GLN B 2 197 ? 106.036 88.849  73.075  1.00 306.14 ? 197 GLN B CG  1 
ATOM   4731  C CD  . GLN B 2 197 ? 105.839 89.116  74.551  1.00 319.37 ? 197 GLN B CD  1 
ATOM   4732  O OE1 . GLN B 2 197 ? 105.004 88.501  75.211  1.00 336.71 ? 197 GLN B OE1 1 
ATOM   4733  N NE2 . GLN B 2 197 ? 106.609 90.048  75.093  1.00 277.20 ? 197 GLN B NE2 1 
ATOM   4734  N N   . ASP B 2 198 ? 108.298 85.665  72.261  1.00 248.00 ? 198 ASP B N   1 
ATOM   4735  C CA  . ASP B 2 198 ? 107.883 84.294  71.989  1.00 302.73 ? 198 ASP B CA  1 
ATOM   4736  C C   . ASP B 2 198 ? 108.270 83.348  73.133  1.00 279.68 ? 198 ASP B C   1 
ATOM   4737  O O   . ASP B 2 198 ? 107.474 82.472  73.487  1.00 303.60 ? 198 ASP B O   1 
ATOM   4738  C CB  . ASP B 2 198 ? 108.467 83.814  70.651  1.00 393.51 ? 198 ASP B CB  1 
ATOM   4739  C CG  . ASP B 2 198 ? 107.954 84.523  69.400  1.00 432.11 ? 198 ASP B CG  1 
ATOM   4740  O OD1 . ASP B 2 198 ? 106.869 85.146  69.460  1.00 440.03 ? 198 ASP B OD1 1 
ATOM   4741  O OD2 . ASP B 2 198 ? 108.651 84.449  68.362  1.00 411.03 ? 198 ASP B OD2 1 
ATOM   4742  N N   . ALA B 2 199 ? 109.478 83.529  73.696  1.00 265.35 ? 199 ALA B N   1 
ATOM   4743  C CA  . ALA B 2 199 ? 110.037 82.660  74.731  1.00 314.45 ? 199 ALA B CA  1 
ATOM   4744  C C   . ALA B 2 199 ? 109.347 82.821  76.099  1.00 305.48 ? 199 ALA B C   1 
ATOM   4745  O O   . ALA B 2 199 ? 108.790 81.855  76.639  1.00 257.06 ? 199 ALA B O   1 
ATOM   4746  C CB  . ALA B 2 199 ? 111.533 82.913  74.825  1.00 283.49 ? 199 ALA B CB  1 
ATOM   4747  N N   . PHE B 2 200 ? 109.376 84.034  76.679  1.00 258.44 ? 200 PHE B N   1 
ATOM   4748  C CA  . PHE B 2 200 ? 109.061 84.220  78.094  1.00 205.53 ? 200 PHE B CA  1 
ATOM   4749  C C   . PHE B 2 200 ? 107.558 84.128  78.404  1.00 239.42 ? 200 PHE B C   1 
ATOM   4750  O O   . PHE B 2 200 ? 107.203 84.057  79.579  1.00 269.75 ? 200 PHE B O   1 
ATOM   4751  C CB  . PHE B 2 200 ? 109.714 85.511  78.603  1.00 178.18 ? 200 PHE B CB  1 
ATOM   4752  C CG  . PHE B 2 200 ? 111.224 85.517  78.536  1.00 226.35 ? 200 PHE B CG  1 
ATOM   4753  C CD1 . PHE B 2 200 ? 111.980 84.418  78.943  1.00 334.33 ? 200 PHE B CD1 1 
ATOM   4754  C CD2 . PHE B 2 200 ? 111.904 86.632  78.071  1.00 238.72 ? 200 PHE B CD2 1 
ATOM   4755  C CE1 . PHE B 2 200 ? 113.368 84.433  78.874  1.00 387.53 ? 200 PHE B CE1 1 
ATOM   4756  C CE2 . PHE B 2 200 ? 113.292 86.643  78.002  1.00 297.12 ? 200 PHE B CE2 1 
ATOM   4757  C CZ  . PHE B 2 200 ? 114.024 85.547  78.402  1.00 360.14 ? 200 PHE B CZ  1 
ATOM   4758  N N   . ALA B 2 201 ? 106.666 84.094  77.401  1.00 285.26 ? 201 ALA B N   1 
ATOM   4759  C CA  . ALA B 2 201 ? 105.268 83.704  77.600  1.00 295.58 ? 201 ALA B CA  1 
ATOM   4760  C C   . ALA B 2 201 ? 105.131 82.327  78.280  1.00 278.87 ? 201 ALA B C   1 
ATOM   4761  O O   . ALA B 2 201 ? 104.124 82.077  78.956  1.00 223.90 ? 201 ALA B O   1 
ATOM   4762  C CB  . ALA B 2 201 ? 104.531 83.747  76.272  1.00 292.64 ? 201 ALA B CB  1 
ATOM   4763  N N   . ALA B 2 202 ? 106.132 81.439  78.107  1.00 291.65 ? 202 ALA B N   1 
ATOM   4764  C CA  . ALA B 2 202 ? 106.190 80.149  78.784  1.00 342.65 ? 202 ALA B CA  1 
ATOM   4765  C C   . ALA B 2 202 ? 106.440 80.309  80.288  1.00 301.27 ? 202 ALA B C   1 
ATOM   4766  O O   . ALA B 2 202 ? 105.810 79.607  81.080  1.00 298.02 ? 202 ALA B O   1 
ATOM   4767  C CB  . ALA B 2 202 ? 107.247 79.276  78.138  1.00 391.73 ? 202 ALA B CB  1 
ATOM   4768  N N   . ALA B 2 203 ? 107.352 81.218  80.676  1.00 265.29 ? 203 ALA B N   1 
ATOM   4769  C CA  . ALA B 2 203 ? 107.712 81.450  82.072  1.00 259.75 ? 203 ALA B CA  1 
ATOM   4770  C C   . ALA B 2 203 ? 106.530 81.980  82.898  1.00 195.21 ? 203 ALA B C   1 
ATOM   4771  O O   . ALA B 2 203 ? 106.356 81.579  84.054  1.00 161.17 ? 203 ALA B O   1 
ATOM   4772  C CB  . ALA B 2 203 ? 108.906 82.373  82.125  1.00 241.71 ? 203 ALA B CB  1 
ATOM   4773  N N   . LYS B 2 204 ? 105.718 82.869  82.304  1.00 175.00 ? 204 LYS B N   1 
ATOM   4774  C CA  . LYS B 2 204 ? 104.485 83.384  82.899  1.00 233.46 ? 204 LYS B CA  1 
ATOM   4775  C C   . LYS B 2 204 ? 103.592 82.266  83.452  1.00 204.42 ? 204 LYS B C   1 
ATOM   4776  O O   . LYS B 2 204 ? 103.194 82.306  84.615  1.00 143.16 ? 204 LYS B O   1 
ATOM   4777  C CB  . LYS B 2 204 ? 103.742 84.210  81.846  1.00 274.45 ? 204 LYS B CB  1 
ATOM   4778  C CG  . LYS B 2 204 ? 102.531 85.006  82.313  1.00 246.21 ? 204 LYS B CG  1 
ATOM   4779  C CD  . LYS B 2 204 ? 101.677 85.492  81.138  1.00 276.70 ? 204 LYS B CD  1 
ATOM   4780  C CE  . LYS B 2 204 ? 102.396 86.426  80.179  1.00 303.57 ? 204 LYS B CE  1 
ATOM   4781  N NZ  . LYS B 2 204 ? 101.478 86.997  79.165  1.00 297.72 ? 204 LYS B NZ  1 
ATOM   4782  N N   . LEU B 2 205 ? 103.282 81.274  82.617  1.00 214.25 ? 205 LEU B N   1 
ATOM   4783  C CA  . LEU B 2 205 ? 102.407 80.184  83.013  1.00 225.99 ? 205 LEU B CA  1 
ATOM   4784  C C   . LEU B 2 205 ? 103.160 79.133  83.834  1.00 161.85 ? 205 LEU B C   1 
ATOM   4785  O O   . LEU B 2 205 ? 102.548 78.504  84.689  1.00 185.97 ? 205 LEU B O   1 
ATOM   4786  C CB  . LEU B 2 205 ? 101.771 79.603  81.741  1.00 309.10 ? 205 LEU B CB  1 
ATOM   4787  C CG  . LEU B 2 205 ? 100.810 80.548  81.017  1.00 319.82 ? 205 LEU B CG  1 
ATOM   4788  C CD1 . LEU B 2 205 ? 100.354 79.952  79.691  1.00 376.02 ? 205 LEU B CD1 1 
ATOM   4789  C CD2 . LEU B 2 205 ? 99.607  80.881  81.887  1.00 264.30 ? 205 LEU B CD2 1 
ATOM   4790  N N   . LEU B 2 206 ? 104.464 78.924  83.598  1.00 175.41 ? 206 LEU B N   1 
ATOM   4791  C CA  . LEU B 2 206 ? 105.232 77.924  84.331  1.00 229.45 ? 206 LEU B CA  1 
ATOM   4792  C C   . LEU B 2 206 ? 105.310 78.280  85.821  1.00 191.51 ? 206 LEU B C   1 
ATOM   4793  O O   . LEU B 2 206 ? 105.047 77.414  86.661  1.00 168.62 ? 206 LEU B O   1 
ATOM   4794  C CB  . LEU B 2 206 ? 106.613 77.779  83.676  1.00 260.62 ? 206 LEU B CB  1 
ATOM   4795  C CG  . LEU B 2 206 ? 107.513 76.692  84.265  1.00 291.23 ? 206 LEU B CG  1 
ATOM   4796  C CD1 . LEU B 2 206 ? 108.370 76.049  83.182  1.00 322.76 ? 206 LEU B CD1 1 
ATOM   4797  C CD2 . LEU B 2 206 ? 108.408 77.236  85.370  1.00 281.70 ? 206 LEU B CD2 1 
ATOM   4798  N N   . ALA B 2 207 ? 105.657 79.538  86.148  1.00 218.72 ? 207 ALA B N   1 
ATOM   4799  C CA  . ALA B 2 207 ? 105.702 80.010  87.533  1.00 213.10 ? 207 ALA B CA  1 
ATOM   4800  C C   . ALA B 2 207 ? 104.327 79.934  88.214  1.00 178.56 ? 207 ALA B C   1 
ATOM   4801  O O   . ALA B 2 207 ? 104.237 79.528  89.373  1.00 204.32 ? 207 ALA B O   1 
ATOM   4802  C CB  . ALA B 2 207 ? 106.233 81.421  87.583  1.00 175.59 ? 207 ALA B CB  1 
ATOM   4803  N N   . LEU B 2 208 ? 103.266 80.323  87.495  1.00 143.60 ? 208 LEU B N   1 
ATOM   4804  C CA  . LEU B 2 208 ? 101.926 80.426  88.050  1.00 150.94 ? 208 LEU B CA  1 
ATOM   4805  C C   . LEU B 2 208 ? 101.307 79.045  88.286  1.00 189.42 ? 208 LEU B C   1 
ATOM   4806  O O   . LEU B 2 208 ? 100.577 78.861  89.252  1.00 194.88 ? 208 LEU B O   1 
ATOM   4807  C CB  . LEU B 2 208 ? 101.078 81.258  87.077  1.00 181.80 ? 208 LEU B CB  1 
ATOM   4808  C CG  . LEU B 2 208 ? 99.840  81.914  87.671  1.00 199.85 ? 208 LEU B CG  1 
ATOM   4809  C CD1 . LEU B 2 208 ? 100.251 82.987  88.672  1.00 233.04 ? 208 LEU B CD1 1 
ATOM   4810  C CD2 . LEU B 2 208 ? 98.986  82.519  86.574  1.00 221.84 ? 208 LEU B CD2 1 
ATOM   4811  N N   . ALA B 2 209 ? 101.583 78.074  87.403  1.00 239.98 ? 209 ALA B N   1 
ATOM   4812  C CA  . ALA B 2 209 ? 101.164 76.690  87.588  1.00 247.19 ? 209 ALA B CA  1 
ATOM   4813  C C   . ALA B 2 209 ? 101.942 76.046  88.737  1.00 179.74 ? 209 ALA B C   1 
ATOM   4814  O O   . ALA B 2 209 ? 101.354 75.307  89.528  1.00 174.78 ? 209 ALA B O   1 
ATOM   4815  C CB  . ALA B 2 209 ? 101.331 75.925  86.288  1.00 282.53 ? 209 ALA B CB  1 
ATOM   4816  N N   . LEU B 2 210 ? 103.255 76.315  88.830  1.00 197.48 ? 210 LEU B N   1 
ATOM   4817  C CA  . LEU B 2 210 ? 104.096 75.750  89.885  1.00 216.17 ? 210 LEU B CA  1 
ATOM   4818  C C   . LEU B 2 210 ? 103.601 76.154  91.280  1.00 166.65 ? 210 LEU B C   1 
ATOM   4819  O O   . LEU B 2 210 ? 103.531 75.313  92.172  1.00 212.54 ? 210 LEU B O   1 
ATOM   4820  C CB  . LEU B 2 210 ? 105.549 76.173  89.646  1.00 242.78 ? 210 LEU B CB  1 
ATOM   4821  C CG  . LEU B 2 210 ? 106.576 75.737  90.686  1.00 263.26 ? 210 LEU B CG  1 
ATOM   4822  C CD1 . LEU B 2 210 ? 106.626 74.222  90.847  1.00 315.11 ? 210 LEU B CD1 1 
ATOM   4823  C CD2 . LEU B 2 210 ? 107.933 76.263  90.275  1.00 271.82 ? 210 LEU B CD2 1 
ATOM   4824  N N   . ILE B 2 211 ? 103.240 77.420  91.463  1.00 173.88 ? 211 ILE B N   1 
ATOM   4825  C CA  . ILE B 2 211 ? 102.605 77.875  92.696  1.00 204.88 ? 211 ILE B CA  1 
ATOM   4826  C C   . ILE B 2 211 ? 101.343 77.056  93.026  1.00 217.74 ? 211 ILE B C   1 
ATOM   4827  O O   . ILE B 2 211 ? 101.142 76.710  94.185  1.00 284.38 ? 211 ILE B O   1 
ATOM   4828  C CB  . ILE B 2 211 ? 102.374 79.405  92.613  1.00 213.18 ? 211 ILE B CB  1 
ATOM   4829  C CG1 . ILE B 2 211 ? 103.733 80.110  92.733  1.00 235.70 ? 211 ILE B CG1 1 
ATOM   4830  C CG2 . ILE B 2 211 ? 101.346 79.945  93.619  1.00 149.05 ? 211 ILE B CG2 1 
ATOM   4831  C CD1 . ILE B 2 211 ? 103.727 81.552  92.333  1.00 238.32 ? 211 ILE B CD1 1 
ATOM   4832  N N   . ILE B 2 212 ? 100.499 76.726  92.042  1.00 222.80 ? 212 ILE B N   1 
ATOM   4833  C CA  . ILE B 2 212 ? 99.274  75.973  92.299  1.00 209.09 ? 212 ILE B CA  1 
ATOM   4834  C C   . ILE B 2 212 ? 99.607  74.516  92.648  1.00 247.79 ? 212 ILE B C   1 
ATOM   4835  O O   . ILE B 2 212 ? 99.004  73.996  93.593  1.00 297.62 ? 212 ILE B O   1 
ATOM   4836  C CB  . ILE B 2 212 ? 98.294  76.108  91.109  1.00 211.42 ? 212 ILE B CB  1 
ATOM   4837  C CG1 . ILE B 2 212 ? 97.715  77.520  91.054  1.00 230.81 ? 212 ILE B CG1 1 
ATOM   4838  C CG2 . ILE B 2 212 ? 97.191  75.061  91.151  1.00 240.58 ? 212 ILE B CG2 1 
ATOM   4839  C CD1 . ILE B 2 212 ? 96.944  77.847  89.791  1.00 282.80 ? 212 ILE B CD1 1 
ATOM   4840  N N   . LEU B 2 213 ? 100.534 73.851  91.919  1.00 268.65 ? 213 LEU B N   1 
ATOM   4841  C CA  . LEU B 2 213 ? 100.830 72.441  92.199  1.00 275.20 ? 213 LEU B CA  1 
ATOM   4842  C C   . LEU B 2 213 ? 101.523 72.298  93.568  1.00 219.53 ? 213 LEU B C   1 
ATOM   4843  O O   . LEU B 2 213 ? 101.264 71.322  94.279  1.00 294.56 ? 213 LEU B O   1 
ATOM   4844  C CB  . LEU B 2 213 ? 101.594 71.786  91.029  1.00 294.81 ? 213 LEU B CB  1 
ATOM   4845  C CG  . LEU B 2 213 ? 103.117 71.944  90.937  1.00 303.49 ? 213 LEU B CG  1 
ATOM   4846  C CD1 . LEU B 2 213 ? 103.870 70.861  91.718  1.00 260.39 ? 213 LEU B CD1 1 
ATOM   4847  C CD2 . LEU B 2 213 ? 103.560 71.924  89.477  1.00 317.74 ? 213 LEU B CD2 1 
ATOM   4848  N N   . LEU B 2 214 ? 102.370 73.262  93.957  1.00 197.41 ? 214 LEU B N   1 
ATOM   4849  C CA  . LEU B 2 214 ? 102.897 73.323  95.319  1.00 231.98 ? 214 LEU B CA  1 
ATOM   4850  C C   . LEU B 2 214 ? 101.771 73.538  96.347  1.00 243.65 ? 214 LEU B C   1 
ATOM   4851  O O   . LEU B 2 214 ? 101.790 72.908  97.401  1.00 297.96 ? 214 LEU B O   1 
ATOM   4852  C CB  . LEU B 2 214 ? 103.975 74.408  95.390  1.00 258.63 ? 214 LEU B CB  1 
ATOM   4853  C CG  . LEU B 2 214 ? 105.269 74.098  94.634  1.00 289.88 ? 214 LEU B CG  1 
ATOM   4854  C CD1 . LEU B 2 214 ? 106.123 75.353  94.504  1.00 316.31 ? 214 LEU B CD1 1 
ATOM   4855  C CD2 . LEU B 2 214 ? 106.064 72.975  95.301  1.00 261.54 ? 214 LEU B CD2 1 
ATOM   4856  N N   . GLY B 2 215 ? 100.784 74.399  96.046  1.00 263.06 ? 215 GLY B N   1 
ATOM   4857  C CA  . GLY B 2 215 ? 99.578  74.567  96.853  1.00 253.55 ? 215 GLY B CA  1 
ATOM   4858  C C   . GLY B 2 215 ? 98.770  73.281  97.045  1.00 297.52 ? 215 GLY B C   1 
ATOM   4859  O O   . GLY B 2 215 ? 98.274  73.029  98.145  1.00 299.04 ? 215 GLY B O   1 
ATOM   4860  N N   . PHE B 2 216 ? 98.651  72.460  95.986  1.00 345.84 ? 216 PHE B N   1 
ATOM   4861  C CA  . PHE B 2 216 ? 97.961  71.175  96.078  1.00 338.62 ? 216 PHE B CA  1 
ATOM   4862  C C   . PHE B 2 216 ? 98.712  70.180  96.975  1.00 287.23 ? 216 PHE B C   1 
ATOM   4863  O O   . PHE B 2 216 ? 98.049  69.534  97.786  1.00 248.18 ? 216 PHE B O   1 
ATOM   4864  C CB  . PHE B 2 216 ? 97.659  70.597  94.685  1.00 334.61 ? 216 PHE B CB  1 
ATOM   4865  C CG  . PHE B 2 216 ? 96.417  71.160  94.031  1.00 356.06 ? 216 PHE B CG  1 
ATOM   4866  C CD1 . PHE B 2 216 ? 95.184  71.093  94.679  1.00 324.96 ? 216 PHE B CD1 1 
ATOM   4867  C CD2 . PHE B 2 216 ? 96.465  71.751  92.772  1.00 434.22 ? 216 PHE B CD2 1 
ATOM   4868  C CE1 . PHE B 2 216 ? 94.032  71.604  94.093  1.00 318.41 ? 216 PHE B CE1 1 
ATOM   4869  C CE2 . PHE B 2 216 ? 95.314  72.266  92.185  1.00 476.59 ? 216 PHE B CE2 1 
ATOM   4870  C CZ  . PHE B 2 216 ? 94.099  72.192  92.845  1.00 427.70 ? 216 PHE B CZ  1 
ATOM   4871  N N   . VAL B 2 217 ? 100.048 70.043  96.863  1.00 297.13 ? 217 VAL B N   1 
ATOM   4872  C CA  . VAL B 2 217 ? 100.775 69.122  97.746  1.00 315.29 ? 217 VAL B CA  1 
ATOM   4873  C C   . VAL B 2 217 ? 100.782 69.633  99.196  1.00 286.27 ? 217 VAL B C   1 
ATOM   4874  O O   . VAL B 2 217 ? 100.814 68.813  100.111 1.00 343.44 ? 217 VAL B O   1 
ATOM   4875  C CB  . VAL B 2 217 ? 102.198 68.758  97.257  1.00 314.40 ? 217 VAL B CB  1 
ATOM   4876  C CG1 . VAL B 2 217 ? 102.143 68.072  95.896  1.00 280.66 ? 217 VAL B CG1 1 
ATOM   4877  C CG2 . VAL B 2 217 ? 103.170 69.930  97.233  1.00 332.34 ? 217 VAL B CG2 1 
ATOM   4878  N N   . GLN B 2 218 ? 100.732 70.955  99.415  1.00 282.19 ? 218 GLN B N   1 
ATOM   4879  C CA  . GLN B 2 218 ? 100.539 71.537  100.743 1.00 310.54 ? 218 GLN B CA  1 
ATOM   4880  C C   . GLN B 2 218 ? 99.212  71.064  101.362 1.00 256.34 ? 218 GLN B C   1 
ATOM   4881  O O   . GLN B 2 218 ? 99.200  70.684  102.539 1.00 278.69 ? 218 GLN B O   1 
ATOM   4882  C CB  . GLN B 2 218 ? 100.662 73.064  100.648 1.00 337.75 ? 218 GLN B CB  1 
ATOM   4883  C CG  . GLN B 2 218 ? 100.441 73.823  101.951 1.00 316.13 ? 218 GLN B CG  1 
ATOM   4884  C CD  . GLN B 2 218 ? 101.524 73.656  102.993 1.00 328.94 ? 218 GLN B CD  1 
ATOM   4885  O OE1 . GLN B 2 218 ? 102.573 73.058  102.756 1.00 309.84 ? 218 GLN B OE1 1 
ATOM   4886  N NE2 . GLN B 2 218 ? 101.270 74.203  104.173 1.00 332.51 ? 218 GLN B NE2 1 
ATOM   4887  N N   . ILE B 2 219 ? 98.113  71.072  100.585 1.00 250.93 ? 219 ILE B N   1 
ATOM   4888  C CA  . ILE B 2 219 ? 96.825  70.533  101.034 1.00 385.66 ? 219 ILE B CA  1 
ATOM   4889  C C   . ILE B 2 219 ? 96.862  68.998  101.185 1.00 502.53 ? 219 ILE B C   1 
ATOM   4890  O O   . ILE B 2 219 ? 96.289  68.475  102.147 1.00 566.90 ? 219 ILE B O   1 
ATOM   4891  C CB  . ILE B 2 219 ? 95.685  71.042  100.114 1.00 370.60 ? 219 ILE B CB  1 
ATOM   4892  C CG1 . ILE B 2 219 ? 95.363  72.510  100.411 1.00 343.26 ? 219 ILE B CG1 1 
ATOM   4893  C CG2 . ILE B 2 219 ? 94.421  70.185  100.184 1.00 388.00 ? 219 ILE B CG2 1 
ATOM   4894  C CD1 . ILE B 2 219 ? 94.659  72.768  101.747 1.00 303.83 ? 219 ILE B CD1 1 
ATOM   4895  N N   . GLY B 2 220 ? 97.515  68.275  100.256 1.00 485.41 ? 220 GLY B N   1 
ATOM   4896  C CA  . GLY B 2 220 ? 97.672  66.822  100.323 1.00 389.24 ? 220 GLY B CA  1 
ATOM   4897  C C   . GLY B 2 220 ? 98.383  66.334  101.591 1.00 399.39 ? 220 GLY B C   1 
ATOM   4898  O O   . GLY B 2 220 ? 98.029  65.281  102.114 1.00 295.93 ? 220 GLY B O   1 
ATOM   4899  N N   . LYS B 2 221 ? 99.376  67.110  102.067 1.00 465.43 ? 221 LYS B N   1 
ATOM   4900  C CA  . LYS B 2 221 ? 100.056 66.898  103.342 1.00 450.91 ? 221 LYS B CA  1 
ATOM   4901  C C   . LYS B 2 221 ? 99.206  67.389  104.522 1.00 441.33 ? 221 LYS B C   1 
ATOM   4902  O O   . LYS B 2 221 ? 99.195  66.733  105.568 1.00 428.32 ? 221 LYS B O   1 
ATOM   4903  C CB  . LYS B 2 221 ? 101.422 67.595  103.289 1.00 413.22 ? 221 LYS B CB  1 
ATOM   4904  C CG  . LYS B 2 221 ? 102.328 67.387  104.493 1.00 401.39 ? 221 LYS B CG  1 
ATOM   4905  C CD  . LYS B 2 221 ? 103.736 67.921  104.290 1.00 391.79 ? 221 LYS B CD  1 
ATOM   4906  C CE  . LYS B 2 221 ? 104.546 67.149  103.268 1.00 366.28 ? 221 LYS B CE  1 
ATOM   4907  N NZ  . LYS B 2 221 ? 105.969 67.561  103.269 1.00 362.76 ? 221 LYS B NZ  1 
ATOM   4908  N N   . GLY B 2 222 ? 98.514  68.534  104.364 1.00 395.65 ? 222 GLY B N   1 
ATOM   4909  C CA  . GLY B 2 222 ? 97.581  69.048  105.362 1.00 317.62 ? 222 GLY B CA  1 
ATOM   4910  C C   . GLY B 2 222 ? 96.237  68.326  105.322 1.00 285.40 ? 222 GLY B C   1 
ATOM   4911  O O   . GLY B 2 222 ? 95.216  68.961  105.676 1.00 235.84 ? 222 GLY B O   1 
ATOM   4912  N N   . PHE B 2 233 ? 89.541  84.546  106.509 1.00 402.54 ? 233 PHE B N   1 
ATOM   4913  C CA  . PHE B 2 233 ? 88.263  83.757  106.541 1.00 329.74 ? 233 PHE B CA  1 
ATOM   4914  C C   . PHE B 2 233 ? 87.038  84.580  106.998 1.00 264.72 ? 233 PHE B C   1 
ATOM   4915  O O   . PHE B 2 233 ? 85.924  84.229  106.609 1.00 174.27 ? 233 PHE B O   1 
ATOM   4916  C CB  . PHE B 2 233 ? 88.449  82.497  107.411 1.00 262.77 ? 233 PHE B CB  1 
ATOM   4917  C CG  . PHE B 2 233 ? 89.520  81.546  106.916 1.00 343.86 ? 233 PHE B CG  1 
ATOM   4918  C CD1 . PHE B 2 233 ? 89.342  80.790  105.757 1.00 360.93 ? 233 PHE B CD1 1 
ATOM   4919  C CD2 . PHE B 2 233 ? 90.727  81.418  107.593 1.00 331.70 ? 233 PHE B CD2 1 
ATOM   4920  C CE1 . PHE B 2 233 ? 90.330  79.918  105.296 1.00 288.43 ? 233 PHE B CE1 1 
ATOM   4921  C CE2 . PHE B 2 233 ? 91.718  80.545  107.138 1.00 295.04 ? 233 PHE B CE2 1 
ATOM   4922  C CZ  . PHE B 2 233 ? 91.521  79.798  105.987 1.00 278.08 ? 233 PHE B CZ  1 
ATOM   4923  N N   . GLU B 2 234 ? 87.236  85.662  107.781 1.00 332.02 ? 234 GLU B N   1 
ATOM   4924  C CA  . GLU B 2 234 ? 86.164  86.497  108.323 1.00 366.63 ? 234 GLU B CA  1 
ATOM   4925  C C   . GLU B 2 234 ? 85.765  87.636  107.365 1.00 353.45 ? 234 GLU B C   1 
ATOM   4926  O O   . GLU B 2 234 ? 84.579  87.971  107.243 1.00 203.44 ? 234 GLU B O   1 
ATOM   4927  C CB  . GLU B 2 234 ? 86.569  87.139  109.662 1.00 393.13 ? 234 GLU B CB  1 
ATOM   4928  C CG  . GLU B 2 234 ? 87.346  86.233  110.621 1.00 374.97 ? 234 GLU B CG  1 
ATOM   4929  C CD  . GLU B 2 234 ? 88.865  86.312  110.531 1.00 362.47 ? 234 GLU B CD  1 
ATOM   4930  O OE1 . GLU B 2 234 ? 89.386  86.481  109.413 1.00 351.72 ? 234 GLU B OE1 1 
ATOM   4931  O OE2 . GLU B 2 234 ? 89.527  86.196  111.581 1.00 396.68 ? 234 GLU B OE2 1 
ATOM   4932  N N   . GLY B 2 235 ? 86.761  88.242  106.692 1.00 411.86 ? 235 GLY B N   1 
ATOM   4933  C CA  . GLY B 2 235 ? 86.621  89.547  106.052 1.00 414.29 ? 235 GLY B CA  1 
ATOM   4934  C C   . GLY B 2 235 ? 86.601  90.698  107.060 1.00 391.10 ? 235 GLY B C   1 
ATOM   4935  O O   . GLY B 2 235 ? 85.563  91.327  107.269 1.00 352.56 ? 235 GLY B O   1 
ATOM   4936  N N   . THR B 2 236 ? 87.767  90.982  107.672 1.00 373.08 ? 236 THR B N   1 
ATOM   4937  C CA  . THR B 2 236 ? 87.869  91.836  108.862 1.00 356.94 ? 236 THR B CA  1 
ATOM   4938  C C   . THR B 2 236 ? 87.757  93.341  108.561 1.00 318.69 ? 236 THR B C   1 
ATOM   4939  O O   . THR B 2 236 ? 87.726  94.135  109.502 1.00 276.50 ? 236 THR B O   1 
ATOM   4940  C CB  . THR B 2 236 ? 89.162  91.543  109.653 1.00 366.09 ? 236 THR B CB  1 
ATOM   4941  O OG1 . THR B 2 236 ? 90.314  91.731  108.821 1.00 426.85 ? 236 THR B OG1 1 
ATOM   4942  C CG2 . THR B 2 236 ? 89.175  90.149  110.246 1.00 301.80 ? 236 THR B CG2 1 
ATOM   4943  N N   . LYS B 2 237 ? 87.706  93.749  107.278 1.00 325.35 ? 237 LYS B N   1 
ATOM   4944  C CA  . LYS B 2 237 ? 87.282  95.093  106.889 1.00 337.95 ? 237 LYS B CA  1 
ATOM   4945  C C   . LYS B 2 237 ? 86.159  94.988  105.860 1.00 314.78 ? 237 LYS B C   1 
ATOM   4946  O O   . LYS B 2 237 ? 86.176  94.080  105.027 1.00 367.77 ? 237 LYS B O   1 
ATOM   4947  C CB  . LYS B 2 237 ? 88.457  95.909  106.327 1.00 397.68 ? 237 LYS B CB  1 
ATOM   4948  C CG  . LYS B 2 237 ? 89.467  96.364  107.372 1.00 420.67 ? 237 LYS B CG  1 
ATOM   4949  C CD  . LYS B 2 237 ? 90.372  97.513  106.910 1.00 370.75 ? 237 LYS B CD  1 
ATOM   4950  C CE  . LYS B 2 237 ? 91.424  97.132  105.884 1.00 325.01 ? 237 LYS B CE  1 
ATOM   4951  N NZ  . LYS B 2 237 ? 92.605  96.473  106.493 1.00 315.99 ? 237 LYS B NZ  1 
ATOM   4952  N N   . LEU B 2 238 ? 85.192  95.923  105.925 1.00 314.54 ? 238 LEU B N   1 
ATOM   4953  C CA  . LEU B 2 238 ? 84.066  95.952  104.991 1.00 367.30 ? 238 LEU B CA  1 
ATOM   4954  C C   . LEU B 2 238 ? 83.655  97.382  104.595 1.00 349.87 ? 238 LEU B C   1 
ATOM   4955  O O   . LEU B 2 238 ? 82.521  97.597  104.162 1.00 324.46 ? 238 LEU B O   1 
ATOM   4956  C CB  . LEU B 2 238 ? 82.916  95.175  105.653 1.00 392.95 ? 238 LEU B CB  1 
ATOM   4957  C CG  . LEU B 2 238 ? 81.829  94.589  104.742 1.00 382.66 ? 238 LEU B CG  1 
ATOM   4958  C CD1 . LEU B 2 238 ? 82.399  93.571  103.763 1.00 388.47 ? 238 LEU B CD1 1 
ATOM   4959  C CD2 . LEU B 2 238 ? 80.716  93.959  105.570 1.00 346.54 ? 238 LEU B CD2 1 
ATOM   4960  N N   . ASP B 2 239 ? 84.569  98.364  104.705 1.00 349.75 ? 239 ASP B N   1 
ATOM   4961  C CA  . ASP B 2 239 ? 84.330  99.720  104.221 1.00 399.00 ? 239 ASP B CA  1 
ATOM   4962  C C   . ASP B 2 239 ? 84.293  99.729  102.687 1.00 418.28 ? 239 ASP B C   1 
ATOM   4963  O O   . ASP B 2 239 ? 85.201  99.202  102.048 1.00 469.15 ? 239 ASP B O   1 
ATOM   4964  C CB  . ASP B 2 239 ? 85.402  100.679 104.760 1.00 428.27 ? 239 ASP B CB  1 
ATOM   4965  C CG  . ASP B 2 239 ? 85.336  102.124 104.273 1.00 430.69 ? 239 ASP B CG  1 
ATOM   4966  O OD1 . ASP B 2 239 ? 84.295  102.527 103.697 1.00 373.12 ? 239 ASP B OD1 1 
ATOM   4967  O OD2 . ASP B 2 239 ? 86.337  102.849 104.469 1.00 417.81 ? 239 ASP B OD2 1 
ATOM   4968  N N   . VAL B 2 240 ? 83.249  100.354 102.105 1.00 375.73 ? 240 VAL B N   1 
ATOM   4969  C CA  . VAL B 2 240 ? 83.122  100.549 100.662 1.00 373.29 ? 240 VAL B CA  1 
ATOM   4970  C C   . VAL B 2 240 ? 84.356  101.272 100.101 1.00 376.97 ? 240 VAL B C   1 
ATOM   4971  O O   . VAL B 2 240 ? 84.792  100.963 98.987  1.00 446.53 ? 240 VAL B O   1 
ATOM   4972  C CB  . VAL B 2 240 ? 81.794  101.275 100.334 1.00 398.39 ? 240 VAL B CB  1 
ATOM   4973  C CG1 . VAL B 2 240 ? 81.737  101.864 98.924  1.00 454.14 ? 240 VAL B CG1 1 
ATOM   4974  C CG2 . VAL B 2 240 ? 80.604  100.350 100.570 1.00 352.69 ? 240 VAL B CG2 1 
ATOM   4975  N N   . GLY B 2 241 ? 84.922  102.228 100.859 1.00 345.85 ? 241 GLY B N   1 
ATOM   4976  C CA  . GLY B 2 241 ? 86.187  102.862 100.501 1.00 334.86 ? 241 GLY B CA  1 
ATOM   4977  C C   . GLY B 2 241 ? 87.308  101.865 100.183 1.00 284.74 ? 241 GLY B C   1 
ATOM   4978  O O   . GLY B 2 241 ? 87.837  101.869 99.069  1.00 179.18 ? 241 GLY B O   1 
ATOM   4979  N N   . ASN B 2 242 ? 87.653  101.017 101.166 1.00 295.55 ? 242 ASN B N   1 
ATOM   4980  C CA  . ASN B 2 242 ? 88.699  100.012 101.005 1.00 255.33 ? 242 ASN B CA  1 
ATOM   4981  C C   . ASN B 2 242 ? 88.323  98.983  99.938  1.00 187.38 ? 242 ASN B C   1 
ATOM   4982  O O   . ASN B 2 242 ? 89.173  98.586  99.155  1.00 207.26 ? 242 ASN B O   1 
ATOM   4983  C CB  . ASN B 2 242 ? 89.041  99.306  102.318 1.00 272.63 ? 242 ASN B CB  1 
ATOM   4984  C CG  . ASN B 2 242 ? 89.668  100.230 103.341 1.00 318.07 ? 242 ASN B CG  1 
ATOM   4985  O OD1 . ASN B 2 242 ? 88.999  100.654 104.282 1.00 374.16 ? 242 ASN B OD1 1 
ATOM   4986  N ND2 . ASN B 2 242 ? 90.939  100.556 103.167 1.00 292.26 ? 242 ASN B ND2 1 
ATOM   4987  N N   . ILE B 2 243 ? 87.064  98.557  99.856  1.00 213.69 ? 243 ILE B N   1 
ATOM   4988  C CA  . ILE B 2 243 ? 86.751  97.472  98.927  1.00 250.62 ? 243 ILE B CA  1 
ATOM   4989  C C   . ILE B 2 243 ? 86.888  97.933  97.458  1.00 236.01 ? 243 ILE B C   1 
ATOM   4990  O O   . ILE B 2 243 ? 87.150  97.102  96.594  1.00 227.25 ? 243 ILE B O   1 
ATOM   4991  C CB  . ILE B 2 243 ? 85.389  96.807  99.265  1.00 286.84 ? 243 ILE B CB  1 
ATOM   4992  C CG1 . ILE B 2 243 ? 85.466  95.293  99.042  1.00 269.91 ? 243 ILE B CG1 1 
ATOM   4993  C CG2 . ILE B 2 243 ? 84.202  97.437  98.538  1.00 274.66 ? 243 ILE B CG2 1 
ATOM   4994  C CD1 . ILE B 2 243 ? 86.401  94.568  100.011 1.00 203.64 ? 243 ILE B CD1 1 
ATOM   4995  N N   . VAL B 2 244 ? 86.749  99.233  97.162  1.00 234.68 ? 244 VAL B N   1 
ATOM   4996  C CA  . VAL B 2 244 ? 87.073  99.772  95.839  1.00 225.22 ? 244 VAL B CA  1 
ATOM   4997  C C   . VAL B 2 244 ? 88.586  99.739  95.582  1.00 218.18 ? 244 VAL B C   1 
ATOM   4998  O O   . VAL B 2 244 ? 88.976  99.530  94.440  1.00 249.09 ? 244 VAL B O   1 
ATOM   4999  C CB  . VAL B 2 244 ? 86.453  101.177 95.657  1.00 254.28 ? 244 VAL B CB  1 
ATOM   5000  C CG1 . VAL B 2 244 ? 87.070  102.022 94.541  1.00 244.12 ? 244 VAL B CG1 1 
ATOM   5001  C CG2 . VAL B 2 244 ? 84.952  101.047 95.448  1.00 256.79 ? 244 VAL B CG2 1 
ATOM   5002  N N   . LEU B 2 245 ? 89.443  99.934  96.596  1.00 205.19 ? 245 LEU B N   1 
ATOM   5003  C CA  . LEU B 2 245 ? 90.889  99.771  96.420  1.00 195.00 ? 245 LEU B CA  1 
ATOM   5004  C C   . LEU B 2 245 ? 91.304  98.293  96.340  1.00 177.45 ? 245 LEU B C   1 
ATOM   5005  O O   . LEU B 2 245 ? 92.324  97.974  95.726  1.00 206.77 ? 245 LEU B O   1 
ATOM   5006  C CB  . LEU B 2 245 ? 91.634  100.480 97.558  1.00 185.89 ? 245 LEU B CB  1 
ATOM   5007  C CG  . LEU B 2 245 ? 91.365  101.975 97.683  1.00 255.77 ? 245 LEU B CG  1 
ATOM   5008  C CD1 . LEU B 2 245 ? 92.305  102.584 98.717  1.00 278.06 ? 245 LEU B CD1 1 
ATOM   5009  C CD2 . LEU B 2 245 ? 91.504  102.681 96.335  1.00 300.88 ? 245 LEU B CD2 1 
ATOM   5010  N N   . ALA B 2 246 ? 90.534  97.388  96.959  1.00 158.97 ? 246 ALA B N   1 
ATOM   5011  C CA  . ALA B 2 246 ? 90.718  95.955  96.777  1.00 157.34 ? 246 ALA B CA  1 
ATOM   5012  C C   . ALA B 2 246 ? 90.357  95.605  95.339  1.00 170.70 ? 246 ALA B C   1 
ATOM   5013  O O   . ALA B 2 246 ? 91.114  94.913  94.688  1.00 180.27 ? 246 ALA B O   1 
ATOM   5014  C CB  . ALA B 2 246 ? 89.874  95.198  97.778  1.00 240.82 ? 246 ALA B CB  1 
ATOM   5015  N N   . LEU B 2 247 ? 89.220  96.106  94.834  1.00 192.73 ? 247 LEU B N   1 
ATOM   5016  C CA  . LEU B 2 247 ? 88.821  95.860  93.457  1.00 217.21 ? 247 LEU B CA  1 
ATOM   5017  C C   . LEU B 2 247 ? 89.855  96.428  92.472  1.00 216.75 ? 247 LEU B C   1 
ATOM   5018  O O   . LEU B 2 247 ? 90.222  95.739  91.538  1.00 188.07 ? 247 LEU B O   1 
ATOM   5019  C CB  . LEU B 2 247 ? 87.426  96.446  93.225  1.00 251.88 ? 247 LEU B CB  1 
ATOM   5020  C CG  . LEU B 2 247 ? 86.273  95.602  93.754  1.00 292.53 ? 247 LEU B CG  1 
ATOM   5021  C CD1 . LEU B 2 247 ? 84.986  96.416  93.729  1.00 387.21 ? 247 LEU B CD1 1 
ATOM   5022  C CD2 . LEU B 2 247 ? 86.120  94.312  92.950  1.00 246.77 ? 247 LEU B CD2 1 
ATOM   5023  N N   . TYR B 2 248 ? 90.348  97.657  92.654  1.00 194.62 ? 248 TYR B N   1 
ATOM   5024  C CA  . TYR B 2 248 ? 91.416  98.185  91.823  1.00 168.50 ? 248 TYR B CA  1 
ATOM   5025  C C   . TYR B 2 248 ? 92.624  97.263  91.789  1.00 145.10 ? 248 TYR B C   1 
ATOM   5026  O O   . TYR B 2 248 ? 93.152  97.027  90.704  1.00 205.51 ? 248 TYR B O   1 
ATOM   5027  C CB  . TYR B 2 248 ? 91.886  99.543  92.356  1.00 198.51 ? 248 TYR B CB  1 
ATOM   5028  C CG  . TYR B 2 248 ? 91.103  100.788 91.957  1.00 236.04 ? 248 TYR B CG  1 
ATOM   5029  C CD1 . TYR B 2 248 ? 90.130  100.781 90.952  1.00 236.20 ? 248 TYR B CD1 1 
ATOM   5030  C CD2 . TYR B 2 248 ? 91.358  102.005 92.597  1.00 224.16 ? 248 TYR B CD2 1 
ATOM   5031  C CE1 . TYR B 2 248 ? 89.450  101.938 90.603  1.00 253.00 ? 248 TYR B CE1 1 
ATOM   5032  C CE2 . TYR B 2 248 ? 90.681  103.167 92.256  1.00 215.58 ? 248 TYR B CE2 1 
ATOM   5033  C CZ  . TYR B 2 248 ? 89.722  103.131 91.254  1.00 275.36 ? 248 TYR B CZ  1 
ATOM   5034  O OH  . TYR B 2 248 ? 89.031  104.259 90.893  1.00 332.51 ? 248 TYR B OH  1 
ATOM   5035  N N   . SER B 2 249 ? 93.085  96.788  92.950  1.00 151.84 ? 249 SER B N   1 
ATOM   5036  C CA  . SER B 2 249 ? 94.240  95.899  93.010  1.00 199.63 ? 249 SER B CA  1 
ATOM   5037  C C   . SER B 2 249 ? 93.949  94.565  92.314  1.00 182.78 ? 249 SER B C   1 
ATOM   5038  O O   . SER B 2 249 ? 94.800  94.023  91.630  1.00 145.86 ? 249 SER B O   1 
ATOM   5039  C CB  . SER B 2 249 ? 94.695  95.686  94.434  1.00 215.95 ? 249 SER B CB  1 
ATOM   5040  O OG  . SER B 2 249 ? 95.022  96.929  95.057  1.00 199.25 ? 249 SER B OG  1 
ATOM   5041  N N   . GLY B 2 250 ? 92.757  94.004  92.466  1.00 179.81 ? 250 GLY B N   1 
ATOM   5042  C CA  . GLY B 2 250 ? 92.471  92.723  91.848  1.00 170.30 ? 250 GLY B CA  1 
ATOM   5043  C C   . GLY B 2 250 ? 92.240  92.857  90.353  1.00 164.03 ? 250 GLY B C   1 
ATOM   5044  O O   . GLY B 2 250 ? 92.629  91.964  89.635  1.00 152.32 ? 250 GLY B O   1 
ATOM   5045  N N   . LEU B 2 251 ? 91.595  93.945  89.903  1.00 191.21 ? 251 LEU B N   1 
ATOM   5046  C CA  . LEU B 2 251 ? 91.297  94.166  88.493  1.00 215.80 ? 251 LEU B CA  1 
ATOM   5047  C C   . LEU B 2 251 ? 92.567  94.407  87.687  1.00 192.97 ? 251 LEU B C   1 
ATOM   5048  O O   . LEU B 2 251 ? 92.584  94.103  86.496  1.00 191.57 ? 251 LEU B O   1 
ATOM   5049  C CB  . LEU B 2 251 ? 90.352  95.364  88.351  1.00 219.78 ? 251 LEU B CB  1 
ATOM   5050  C CG  . LEU B 2 251 ? 88.879  95.095  88.625  1.00 273.87 ? 251 LEU B CG  1 
ATOM   5051  C CD1 . LEU B 2 251 ? 88.075  96.387  88.599  1.00 352.90 ? 251 LEU B CD1 1 
ATOM   5052  C CD2 . LEU B 2 251 ? 88.297  94.115  87.617  1.00 253.51 ? 251 LEU B CD2 1 
ATOM   5053  N N   . PHE B 2 252 ? 93.612  94.957  88.316  1.00 162.99 ? 252 PHE B N   1 
ATOM   5054  C CA  . PHE B 2 252 ? 94.872  95.186  87.632  1.00 175.21 ? 252 PHE B CA  1 
ATOM   5055  C C   . PHE B 2 252 ? 95.388  93.917  86.942  1.00 170.08 ? 252 PHE B C   1 
ATOM   5056  O O   . PHE B 2 252 ? 95.886  94.037  85.814  1.00 268.72 ? 252 PHE B O   1 
ATOM   5057  C CB  . PHE B 2 252 ? 95.923  95.736  88.597  1.00 178.98 ? 252 PHE B CB  1 
ATOM   5058  C CG  . PHE B 2 252 ? 97.242  96.023  87.933  1.00 173.64 ? 252 PHE B CG  1 
ATOM   5059  C CD1 . PHE B 2 252 ? 98.208  95.034  87.788  1.00 177.46 ? 252 PHE B CD1 1 
ATOM   5060  C CD2 . PHE B 2 252 ? 97.487  97.281  87.427  1.00 174.95 ? 252 PHE B CD2 1 
ATOM   5061  C CE1 . PHE B 2 252 ? 99.408  95.306  87.165  1.00 171.77 ? 252 PHE B CE1 1 
ATOM   5062  C CE2 . PHE B 2 252 ? 98.689  97.561  86.811  1.00 185.01 ? 252 PHE B CE2 1 
ATOM   5063  C CZ  . PHE B 2 252 ? 99.637  96.569  86.679  1.00 208.87 ? 252 PHE B CZ  1 
ATOM   5064  N N   . ALA B 2 253 ? 95.287  92.737  87.582  1.00 101.18 ? 253 ALA B N   1 
ATOM   5065  C CA  . ALA B 2 253 ? 95.805  91.505  86.990  1.00 133.75 ? 253 ALA B CA  1 
ATOM   5066  C C   . ALA B 2 253 ? 95.046  91.101  85.720  1.00 175.10 ? 253 ALA B C   1 
ATOM   5067  O O   . ALA B 2 253 ? 95.671  90.600  84.785  1.00 220.46 ? 253 ALA B O   1 
ATOM   5068  C CB  . ALA B 2 253 ? 95.808  90.384  87.975  1.00 160.91 ? 253 ALA B CB  1 
ATOM   5069  N N   . TYR B 2 254 ? 93.735  91.343  85.642  1.00 125.13 ? 254 TYR B N   1 
ATOM   5070  C CA  . TYR B 2 254 ? 93.015  91.061  84.407  1.00 161.96 ? 254 TYR B CA  1 
ATOM   5071  C C   . TYR B 2 254 ? 93.227  92.055  83.245  1.00 174.86 ? 254 TYR B C   1 
ATOM   5072  O O   . TYR B 2 254 ? 92.534  91.948  82.224  1.00 258.50 ? 254 TYR B O   1 
ATOM   5073  C CB  . TYR B 2 254 ? 91.534  91.073  84.798  1.00 192.54 ? 254 TYR B CB  1 
ATOM   5074  C CG  . TYR B 2 254 ? 91.057  89.957  85.707  1.00 176.38 ? 254 TYR B CG  1 
ATOM   5075  C CD1 . TYR B 2 254 ? 90.616  88.736  85.193  1.00 181.91 ? 254 TYR B CD1 1 
ATOM   5076  C CD2 . TYR B 2 254 ? 91.039  90.135  87.073  1.00 199.16 ? 254 TYR B CD2 1 
ATOM   5077  C CE1 . TYR B 2 254 ? 90.177  87.715  86.015  1.00 176.21 ? 254 TYR B CE1 1 
ATOM   5078  C CE2 . TYR B 2 254 ? 90.598  89.124  87.911  1.00 219.27 ? 254 TYR B CE2 1 
ATOM   5079  C CZ  . TYR B 2 254 ? 90.167  87.917  87.381  1.00 204.66 ? 254 TYR B CZ  1 
ATOM   5080  O OH  . TYR B 2 254 ? 89.737  86.945  88.225  1.00 221.91 ? 254 TYR B OH  1 
ATOM   5081  N N   . GLY B 2 255 ? 94.141  93.033  83.337  1.00 222.19 ? 255 GLY B N   1 
ATOM   5082  C CA  . GLY B 2 255 ? 94.020  94.269  82.563  1.00 281.67 ? 255 GLY B CA  1 
ATOM   5083  C C   . GLY B 2 255 ? 94.459  94.207  81.091  1.00 322.78 ? 255 GLY B C   1 
ATOM   5084  O O   . GLY B 2 255 ? 94.918  95.231  80.568  1.00 421.58 ? 255 GLY B O   1 
ATOM   5085  N N   . GLY B 2 256 ? 94.304  93.041  80.425  1.00 275.16 ? 256 GLY B N   1 
ATOM   5086  C CA  . GLY B 2 256 ? 94.676  92.830  79.029  1.00 262.88 ? 256 GLY B CA  1 
ATOM   5087  C C   . GLY B 2 256 ? 93.530  93.029  78.026  1.00 236.61 ? 256 GLY B C   1 
ATOM   5088  O O   . GLY B 2 256 ? 93.776  93.441  76.887  1.00 355.86 ? 256 GLY B O   1 
ATOM   5089  N N   . TRP B 2 257 ? 92.285  92.750  78.438  1.00 191.75 ? 257 TRP B N   1 
ATOM   5090  C CA  . TRP B 2 257 ? 91.168  92.582  77.498  1.00 251.98 ? 257 TRP B CA  1 
ATOM   5091  C C   . TRP B 2 257 ? 90.772  93.838  76.679  1.00 225.23 ? 257 TRP B C   1 
ATOM   5092  O O   . TRP B 2 257 ? 90.278  93.727  75.553  1.00 160.53 ? 257 TRP B O   1 
ATOM   5093  C CB  . TRP B 2 257 ? 89.952  91.996  78.236  1.00 223.82 ? 257 TRP B CB  1 
ATOM   5094  C CG  . TRP B 2 257 ? 89.536  92.656  79.522  1.00 177.56 ? 257 TRP B CG  1 
ATOM   5095  C CD1 . TRP B 2 257 ? 89.804  92.201  80.778  1.00 190.05 ? 257 TRP B CD1 1 
ATOM   5096  C CD2 . TRP B 2 257 ? 88.749  93.855  79.692  1.00 190.34 ? 257 TRP B CD2 1 
ATOM   5097  N NE1 . TRP B 2 257 ? 89.261  93.032  81.727  1.00 191.40 ? 257 TRP B NE1 1 
ATOM   5098  C CE2 . TRP B 2 257 ? 88.608  94.054  81.086  1.00 196.99 ? 257 TRP B CE2 1 
ATOM   5099  C CE3 . TRP B 2 257 ? 88.152  94.777  78.818  1.00 199.24 ? 257 TRP B CE3 1 
ATOM   5100  C CZ2 . TRP B 2 257 ? 87.891  95.136  81.597  1.00 226.81 ? 257 TRP B CZ2 1 
ATOM   5101  C CZ3 . TRP B 2 257 ? 87.442  95.846  79.329  1.00 216.74 ? 257 TRP B CZ3 1 
ATOM   5102  C CH2 . TRP B 2 257 ? 87.307  96.016  80.703  1.00 234.38 ? 257 TRP B CH2 1 
ATOM   5103  N N   . ASN B 2 258 ? 90.994  95.040  77.215  1.00 224.59 ? 258 ASN B N   1 
ATOM   5104  C CA  . ASN B 2 258 ? 90.667  96.276  76.508  1.00 253.46 ? 258 ASN B CA  1 
ATOM   5105  C C   . ASN B 2 258 ? 91.673  96.618  75.397  1.00 323.44 ? 258 ASN B C   1 
ATOM   5106  O O   . ASN B 2 258 ? 91.347  97.434  74.535  1.00 277.20 ? 258 ASN B O   1 
ATOM   5107  C CB  . ASN B 2 258 ? 90.488  97.443  77.489  1.00 284.19 ? 258 ASN B CB  1 
ATOM   5108  C CG  . ASN B 2 258 ? 91.639  97.673  78.452  1.00 317.69 ? 258 ASN B CG  1 
ATOM   5109  O OD1 . ASN B 2 258 ? 92.078  96.747  79.136  1.00 230.94 ? 258 ASN B OD1 1 
ATOM   5110  N ND2 . ASN B 2 258 ? 92.114  98.907  78.539  1.00 355.70 ? 258 ASN B ND2 1 
ATOM   5111  N N   . TYR B 2 259 ? 92.877  96.013  75.390  1.00 404.27 ? 259 TYR B N   1 
ATOM   5112  C CA  . TYR B 2 259 ? 93.915  96.338  74.410  1.00 417.11 ? 259 TYR B CA  1 
ATOM   5113  C C   . TYR B 2 259 ? 93.891  95.469  73.143  1.00 401.87 ? 259 TYR B C   1 
ATOM   5114  O O   . TYR B 2 259 ? 94.220  95.967  72.059  1.00 424.72 ? 259 TYR B O   1 
ATOM   5115  C CB  . TYR B 2 259 ? 95.311  96.172  75.028  1.00 424.63 ? 259 TYR B CB  1 
ATOM   5116  C CG  . TYR B 2 259 ? 95.665  96.996  76.262  1.00 478.42 ? 259 TYR B CG  1 
ATOM   5117  C CD1 . TYR B 2 259 ? 95.126  98.266  76.492  1.00 514.14 ? 259 TYR B CD1 1 
ATOM   5118  C CD2 . TYR B 2 259 ? 96.563  96.496  77.208  1.00 536.55 ? 259 TYR B CD2 1 
ATOM   5119  C CE1 . TYR B 2 259 ? 95.468  98.997  77.625  1.00 542.13 ? 259 TYR B CE1 1 
ATOM   5120  C CE2 . TYR B 2 259 ? 96.907  97.219  78.342  1.00 583.42 ? 259 TYR B CE2 1 
ATOM   5121  C CZ  . TYR B 2 259 ? 96.357  98.474  78.554  1.00 581.71 ? 259 TYR B CZ  1 
ATOM   5122  O OH  . TYR B 2 259 ? 96.701  99.187  79.672  1.00 605.57 ? 259 TYR B OH  1 
ATOM   5123  N N   . LEU B 2 260 ? 93.541  94.174  73.280  1.00 419.18 ? 260 LEU B N   1 
ATOM   5124  C CA  . LEU B 2 260 ? 93.988  93.139  72.340  1.00 472.13 ? 260 LEU B CA  1 
ATOM   5125  C C   . LEU B 2 260 ? 92.947  92.050  72.039  1.00 389.25 ? 260 LEU B C   1 
ATOM   5126  O O   . LEU B 2 260 ? 93.221  91.187  71.204  1.00 427.99 ? 260 LEU B O   1 
ATOM   5127  C CB  . LEU B 2 260 ? 95.263  92.500  72.919  1.00 550.99 ? 260 LEU B CB  1 
ATOM   5128  C CG  . LEU B 2 260 ? 96.570  93.279  72.732  1.00 587.08 ? 260 LEU B CG  1 
ATOM   5129  C CD1 . LEU B 2 260 ? 97.641  92.779  73.691  1.00 606.44 ? 260 LEU B CD1 1 
ATOM   5130  C CD2 . LEU B 2 260 ? 97.089  93.189  71.301  1.00 595.25 ? 260 LEU B CD2 1 
ATOM   5131  N N   . ASN B 2 261 ? 91.765  92.074  72.666  1.00 273.17 ? 261 ASN B N   1 
ATOM   5132  C CA  . ASN B 2 261 ? 90.830  90.959  72.614  1.00 297.27 ? 261 ASN B CA  1 
ATOM   5133  C C   . ASN B 2 261 ? 90.407  90.595  71.176  1.00 405.61 ? 261 ASN B C   1 
ATOM   5134  O O   . ASN B 2 261 ? 90.225  89.408  70.851  1.00 465.19 ? 261 ASN B O   1 
ATOM   5135  C CB  . ASN B 2 261 ? 89.642  91.318  73.500  1.00 302.30 ? 261 ASN B CB  1 
ATOM   5136  C CG  . ASN B 2 261 ? 88.641  90.196  73.568  1.00 366.91 ? 261 ASN B CG  1 
ATOM   5137  O OD1 . ASN B 2 261 ? 88.923  89.180  74.182  1.00 335.01 ? 261 ASN B OD1 1 
ATOM   5138  N ND2 . ASN B 2 261 ? 87.490  90.359  72.939  1.00 434.54 ? 261 ASN B ND2 1 
ATOM   5139  N N   . PHE B 2 262 ? 90.261  91.630  70.322  1.00 421.64 ? 262 PHE B N   1 
ATOM   5140  C CA  . PHE B 2 262 ? 89.917  91.528  68.903  1.00 367.65 ? 262 PHE B CA  1 
ATOM   5141  C C   . PHE B 2 262 ? 90.887  90.667  68.076  1.00 322.31 ? 262 PHE B C   1 
ATOM   5142  O O   . PHE B 2 262 ? 90.469  90.170  67.034  1.00 318.16 ? 262 PHE B O   1 
ATOM   5143  C CB  . PHE B 2 262 ? 89.801  92.929  68.282  1.00 361.22 ? 262 PHE B CB  1 
ATOM   5144  C CG  . PHE B 2 262 ? 91.008  93.823  68.468  1.00 404.97 ? 262 PHE B CG  1 
ATOM   5145  C CD1 . PHE B 2 262 ? 92.155  93.662  67.692  1.00 346.53 ? 262 PHE B CD1 1 
ATOM   5146  C CD2 . PHE B 2 262 ? 91.006  94.824  69.438  1.00 445.52 ? 262 PHE B CD2 1 
ATOM   5147  C CE1 . PHE B 2 262 ? 93.262  94.485  67.873  1.00 305.04 ? 262 PHE B CE1 1 
ATOM   5148  C CE2 . PHE B 2 262 ? 92.114  95.643  69.624  1.00 434.36 ? 262 PHE B CE2 1 
ATOM   5149  C CZ  . PHE B 2 262 ? 93.242  95.476  68.840  1.00 378.45 ? 262 PHE B CZ  1 
ATOM   5150  N N   . VAL B 2 263 ? 92.155  90.490  68.506  1.00 287.09 ? 263 VAL B N   1 
ATOM   5151  C CA  . VAL B 2 263 ? 93.139  89.643  67.822  1.00 262.75 ? 263 VAL B CA  1 
ATOM   5152  C C   . VAL B 2 263 ? 92.587  88.240  67.527  1.00 295.58 ? 263 VAL B C   1 
ATOM   5153  O O   . VAL B 2 263 ? 92.881  87.684  66.458  1.00 411.10 ? 263 VAL B O   1 
ATOM   5154  C CB  . VAL B 2 263 ? 94.465  89.591  68.617  1.00 285.82 ? 263 VAL B CB  1 
ATOM   5155  C CG1 . VAL B 2 263 ? 95.401  88.441  68.238  1.00 298.66 ? 263 VAL B CG1 1 
ATOM   5156  C CG2 . VAL B 2 263 ? 95.187  90.925  68.488  1.00 329.50 ? 263 VAL B CG2 1 
ATOM   5157  N N   . THR B 2 264 ? 91.791  87.674  68.454  1.00 286.16 ? 264 THR B N   1 
ATOM   5158  C CA  . THR B 2 264 ? 91.262  86.323  68.299  1.00 307.13 ? 264 THR B CA  1 
ATOM   5159  C C   . THR B 2 264 ? 90.282  86.193  67.122  1.00 358.67 ? 264 THR B C   1 
ATOM   5160  O O   . THR B 2 264 ? 90.141  85.078  66.617  1.00 472.99 ? 264 THR B O   1 
ATOM   5161  C CB  . THR B 2 264 ? 90.639  85.812  69.603  1.00 375.32 ? 264 THR B CB  1 
ATOM   5162  O OG1 . THR B 2 264 ? 89.589  86.695  69.998  1.00 402.01 ? 264 THR B OG1 1 
ATOM   5163  C CG2 . THR B 2 264 ? 91.665  85.679  70.711  1.00 401.99 ? 264 THR B CG2 1 
ATOM   5164  N N   . GLU B 2 265 ? 89.632  87.292  66.677  1.00 336.41 ? 265 GLU B N   1 
ATOM   5165  C CA  . GLU B 2 265 ? 88.732  87.283  65.515  1.00 364.21 ? 265 GLU B CA  1 
ATOM   5166  C C   . GLU B 2 265 ? 89.456  86.951  64.189  1.00 330.34 ? 265 GLU B C   1 
ATOM   5167  O O   . GLU B 2 265 ? 88.813  86.488  63.242  1.00 204.98 ? 265 GLU B O   1 
ATOM   5168  C CB  . GLU B 2 265 ? 87.960  88.613  65.478  1.00 382.12 ? 265 GLU B CB  1 
ATOM   5169  C CG  . GLU B 2 265 ? 86.918  88.741  64.364  1.00 436.86 ? 265 GLU B CG  1 
ATOM   5170  C CD  . GLU B 2 265 ? 87.356  89.370  63.046  1.00 455.62 ? 265 GLU B CD  1 
ATOM   5171  O OE1 . GLU B 2 265 ? 88.511  89.808  62.942  1.00 419.53 ? 265 GLU B OE1 1 
ATOM   5172  O OE2 . GLU B 2 265 ? 86.529  89.424  62.113  1.00 488.74 ? 265 GLU B OE2 1 
ATOM   5173  N N   . GLU B 2 266 ? 90.784  87.151  64.102  1.00 338.42 ? 266 GLU B N   1 
ATOM   5174  C CA  . GLU B 2 266 ? 91.557  86.808  62.909  1.00 301.13 ? 266 GLU B CA  1 
ATOM   5175  C C   . GLU B 2 266 ? 91.874  85.301  62.799  1.00 347.30 ? 266 GLU B C   1 
ATOM   5176  O O   . GLU B 2 266 ? 92.488  84.902  61.806  1.00 286.20 ? 266 GLU B O   1 
ATOM   5177  C CB  . GLU B 2 266 ? 92.851  87.630  62.892  1.00 351.65 ? 266 GLU B CB  1 
ATOM   5178  C CG  . GLU B 2 266 ? 92.611  89.136  62.917  1.00 374.20 ? 266 GLU B CG  1 
ATOM   5179  C CD  . GLU B 2 266 ? 93.822  90.041  62.749  1.00 409.29 ? 266 GLU B CD  1 
ATOM   5180  O OE1 . GLU B 2 266 ? 94.868  89.755  63.370  1.00 425.91 ? 266 GLU B OE1 1 
ATOM   5181  O OE2 . GLU B 2 266 ? 93.715  91.043  62.003  1.00 394.03 ? 266 GLU B OE2 1 
ATOM   5182  N N   . MET B 2 267 ? 91.489  84.463  63.794  1.00 442.47 ? 267 MET B N   1 
ATOM   5183  C CA  . MET B 2 267 ? 91.646  83.004  63.742  1.00 437.84 ? 267 MET B CA  1 
ATOM   5184  C C   . MET B 2 267 ? 90.388  82.222  64.176  1.00 385.22 ? 267 MET B C   1 
ATOM   5185  O O   . MET B 2 267 ? 90.254  81.049  63.806  1.00 222.49 ? 267 MET B O   1 
ATOM   5186  C CB  . MET B 2 267 ? 92.828  82.582  64.630  1.00 460.90 ? 267 MET B CB  1 
ATOM   5187  C CG  . MET B 2 267 ? 94.208  82.986  64.098  1.00 441.27 ? 267 MET B CG  1 
ATOM   5188  S SD  . MET B 2 267 ? 94.776  84.643  64.612  1.00 483.08 ? 267 MET B SD  1 
ATOM   5189  C CE  . MET B 2 267 ? 95.132  84.386  66.350  1.00 499.72 ? 267 MET B CE  1 
ATOM   5190  N N   . ILE B 2 268 ? 89.480  82.838  64.966  1.00 473.03 ? 268 ILE B N   1 
ATOM   5191  C CA  . ILE B 2 268 ? 88.154  82.303  65.273  1.00 501.91 ? 268 ILE B CA  1 
ATOM   5192  C C   . ILE B 2 268 ? 87.144  83.035  64.387  1.00 484.13 ? 268 ILE B C   1 
ATOM   5193  O O   . ILE B 2 268 ? 86.820  84.195  64.643  1.00 491.81 ? 268 ILE B O   1 
ATOM   5194  C CB  . ILE B 2 268 ? 87.826  82.460  66.780  1.00 513.15 ? 268 ILE B CB  1 
ATOM   5195  C CG1 . ILE B 2 268 ? 88.866  81.787  67.688  1.00 534.55 ? 268 ILE B CG1 1 
ATOM   5196  C CG2 . ILE B 2 268 ? 86.409  81.981  67.110  1.00 462.90 ? 268 ILE B CG2 1 
ATOM   5197  C CD1 . ILE B 2 268 ? 89.044  80.311  67.458  1.00 521.43 ? 268 ILE B CD1 1 
ATOM   5198  N N   . ASN B 2 269 ? 86.625  82.354  63.353  1.00 422.46 ? 269 ASN B N   1 
ATOM   5199  C CA  . ASN B 2 269 ? 86.007  83.039  62.218  1.00 389.49 ? 269 ASN B CA  1 
ATOM   5200  C C   . ASN B 2 269 ? 84.572  83.512  62.535  1.00 336.58 ? 269 ASN B C   1 
ATOM   5201  O O   . ASN B 2 269 ? 84.278  84.697  62.317  1.00 239.43 ? 269 ASN B O   1 
ATOM   5202  C CB  . ASN B 2 269 ? 86.093  82.203  60.932  1.00 411.88 ? 269 ASN B CB  1 
ATOM   5203  C CG  . ASN B 2 269 ? 87.419  81.483  60.753  1.00 374.58 ? 269 ASN B CG  1 
ATOM   5204  O OD1 . ASN B 2 269 ? 87.606  80.372  61.252  1.00 307.65 ? 269 ASN B OD1 1 
ATOM   5205  N ND2 . ASN B 2 269 ? 88.348  82.101  60.043  1.00 335.18 ? 269 ASN B ND2 1 
ATOM   5206  N N   . PRO B 2 270 ? 83.629  82.660  63.039  1.00 356.84 ? 270 PRO B N   1 
ATOM   5207  C CA  . PRO B 2 270 ? 82.258  83.106  63.321  1.00 336.45 ? 270 PRO B CA  1 
ATOM   5208  C C   . PRO B 2 270 ? 82.160  84.120  64.470  1.00 270.23 ? 270 PRO B C   1 
ATOM   5209  O O   . PRO B 2 270 ? 82.716  83.918  65.547  1.00 224.41 ? 270 PRO B O   1 
ATOM   5210  C CB  . PRO B 2 270 ? 81.501  81.807  63.680  1.00 333.52 ? 270 PRO B CB  1 
ATOM   5211  C CG  . PRO B 2 270 ? 82.394  80.683  63.199  1.00 315.28 ? 270 PRO B CG  1 
ATOM   5212  C CD  . PRO B 2 270 ? 83.795  81.229  63.366  1.00 344.44 ? 270 PRO B CD  1 
ATOM   5213  N N   . TYR B 2 271 ? 81.424  85.214  64.236  1.00 259.80 ? 271 TYR B N   1 
ATOM   5214  C CA  . TYR B 2 271 ? 81.263  86.297  65.205  1.00 264.09 ? 271 TYR B CA  1 
ATOM   5215  C C   . TYR B 2 271 ? 80.586  85.850  66.507  1.00 256.25 ? 271 TYR B C   1 
ATOM   5216  O O   . TYR B 2 271 ? 80.893  86.435  67.541  1.00 332.61 ? 271 TYR B O   1 
ATOM   5217  C CB  . TYR B 2 271 ? 80.546  87.469  64.523  1.00 253.51 ? 271 TYR B CB  1 
ATOM   5218  C CG  . TYR B 2 271 ? 81.497  88.108  63.523  1.00 289.34 ? 271 TYR B CG  1 
ATOM   5219  C CD1 . TYR B 2 271 ? 82.534  88.928  63.959  1.00 372.25 ? 271 TYR B CD1 1 
ATOM   5220  C CD2 . TYR B 2 271 ? 81.389  87.873  62.155  1.00 316.81 ? 271 TYR B CD2 1 
ATOM   5221  C CE1 . TYR B 2 271 ? 83.420  89.511  63.065  1.00 426.89 ? 271 TYR B CE1 1 
ATOM   5222  C CE2 . TYR B 2 271 ? 82.270  88.452  61.249  1.00 350.12 ? 271 TYR B CE2 1 
ATOM   5223  C CZ  . TYR B 2 271 ? 83.290  89.275  61.706  1.00 403.60 ? 271 TYR B CZ  1 
ATOM   5224  O OH  . TYR B 2 271 ? 84.185  89.867  60.856  1.00 428.40 ? 271 TYR B OH  1 
ATOM   5225  N N   . ARG B 2 272 ? 79.709  84.833  66.496  1.00 263.37 ? 272 ARG B N   1 
ATOM   5226  C CA  . ARG B 2 272 ? 79.126  84.318  67.738  1.00 319.05 ? 272 ARG B CA  1 
ATOM   5227  C C   . ARG B 2 272 ? 80.128  83.462  68.540  1.00 357.18 ? 272 ARG B C   1 
ATOM   5228  O O   . ARG B 2 272 ? 79.898  83.238  69.732  1.00 416.02 ? 272 ARG B O   1 
ATOM   5229  C CB  . ARG B 2 272 ? 77.817  83.572  67.443  1.00 353.61 ? 272 ARG B CB  1 
ATOM   5230  C CG  . ARG B 2 272 ? 76.959  83.303  68.676  1.00 385.54 ? 272 ARG B CG  1 
ATOM   5231  C CD  . ARG B 2 272 ? 75.558  82.803  68.387  1.00 421.95 ? 272 ARG B CD  1 
ATOM   5232  N NE  . ARG B 2 272 ? 74.771  82.697  69.618  1.00 421.14 ? 272 ARG B NE  1 
ATOM   5233  C CZ  . ARG B 2 272 ? 74.535  81.575  70.305  1.00 386.80 ? 272 ARG B CZ  1 
ATOM   5234  N NH1 . ARG B 2 272 ? 73.746  81.596  71.371  1.00 284.31 ? 272 ARG B NH1 1 
ATOM   5235  N NH2 . ARG B 2 272 ? 75.081  80.428  69.930  1.00 389.98 ? 272 ARG B NH2 1 
ATOM   5236  N N   . ASN B 2 273 ? 81.234  82.986  67.930  1.00 355.67 ? 273 ASN B N   1 
ATOM   5237  C CA  . ASN B 2 273 ? 82.251  82.198  68.627  1.00 364.44 ? 273 ASN B CA  1 
ATOM   5238  C C   . ASN B 2 273 ? 83.229  83.082  69.434  1.00 288.76 ? 273 ASN B C   1 
ATOM   5239  O O   . ASN B 2 273 ? 83.869  82.571  70.354  1.00 192.68 ? 273 ASN B O   1 
ATOM   5240  C CB  . ASN B 2 273 ? 82.970  81.242  67.660  1.00 397.04 ? 273 ASN B CB  1 
ATOM   5241  C CG  . ASN B 2 273 ? 82.105  80.107  67.119  1.00 367.44 ? 273 ASN B CG  1 
ATOM   5242  O OD1 . ASN B 2 273 ? 80.876  80.105  67.245  1.00 267.83 ? 273 ASN B OD1 1 
ATOM   5243  N ND2 . ASN B 2 273 ? 82.742  79.120  66.503  1.00 326.19 ? 273 ASN B ND2 1 
ATOM   5244  N N   . LEU B 2 274 ? 83.351  84.392  69.137  1.00 298.85 ? 274 LEU B N   1 
ATOM   5245  C CA  . LEU B 2 274 ? 84.187  85.297  69.932  1.00 288.92 ? 274 LEU B CA  1 
ATOM   5246  C C   . LEU B 2 274 ? 83.633  85.460  71.362  1.00 248.27 ? 274 LEU B C   1 
ATOM   5247  O O   . LEU B 2 274 ? 84.394  85.303  72.317  1.00 310.30 ? 274 LEU B O   1 
ATOM   5248  C CB  . LEU B 2 274 ? 84.354  86.632  69.184  1.00 303.52 ? 274 LEU B CB  1 
ATOM   5249  C CG  . LEU B 2 274 ? 85.090  87.746  69.934  1.00 285.02 ? 274 LEU B CG  1 
ATOM   5250  C CD1 . LEU B 2 274 ? 86.533  87.354  70.178  1.00 304.04 ? 274 LEU B CD1 1 
ATOM   5251  C CD2 . LEU B 2 274 ? 85.041  89.063  69.182  1.00 257.93 ? 274 LEU B CD2 1 
ATOM   5252  N N   . PRO B 2 275 ? 82.337  85.780  71.611  1.00 227.50 ? 275 PRO B N   1 
ATOM   5253  C CA  . PRO B 2 275 ? 81.729  85.605  72.938  1.00 271.62 ? 275 PRO B CA  1 
ATOM   5254  C C   . PRO B 2 275 ? 81.944  84.240  73.602  1.00 264.51 ? 275 PRO B C   1 
ATOM   5255  O O   . PRO B 2 275 ? 82.152  84.216  74.803  1.00 312.58 ? 275 PRO B O   1 
ATOM   5256  C CB  . PRO B 2 275 ? 80.232  85.883  72.702  1.00 272.46 ? 275 PRO B CB  1 
ATOM   5257  C CG  . PRO B 2 275 ? 80.244  86.851  71.554  1.00 261.96 ? 275 PRO B CG  1 
ATOM   5258  C CD  . PRO B 2 275 ? 81.375  86.362  70.670  1.00 257.68 ? 275 PRO B CD  1 
ATOM   5259  N N   . LEU B 2 276 ? 81.932  83.114  72.875  1.00 202.39 ? 276 LEU B N   1 
ATOM   5260  C CA  . LEU B 2 276 ? 82.233  81.832  73.515  1.00 232.27 ? 276 LEU B CA  1 
ATOM   5261  C C   . LEU B 2 276 ? 83.689  81.770  74.014  1.00 301.96 ? 276 LEU B C   1 
ATOM   5262  O O   . LEU B 2 276 ? 83.911  81.257  75.108  1.00 294.16 ? 276 LEU B O   1 
ATOM   5263  C CB  . LEU B 2 276 ? 81.904  80.672  72.567  1.00 284.84 ? 276 LEU B CB  1 
ATOM   5264  C CG  . LEU B 2 276 ? 80.408  80.492  72.270  1.00 337.85 ? 276 LEU B CG  1 
ATOM   5265  C CD1 . LEU B 2 276 ? 80.186  79.327  71.311  1.00 400.42 ? 276 LEU B CD1 1 
ATOM   5266  C CD2 . LEU B 2 276 ? 79.579  80.291  73.545  1.00 276.21 ? 276 LEU B CD2 1 
ATOM   5267  N N   . ALA B 2 277 ? 84.669  82.290  73.254  1.00 349.15 ? 277 ALA B N   1 
ATOM   5268  C CA  . ALA B 2 277 ? 86.067  82.343  73.693  1.00 323.19 ? 277 ALA B CA  1 
ATOM   5269  C C   . ALA B 2 277 ? 86.241  83.185  74.967  1.00 229.86 ? 277 ALA B C   1 
ATOM   5270  O O   . ALA B 2 277 ? 86.971  82.780  75.863  1.00 172.23 ? 277 ALA B O   1 
ATOM   5271  C CB  . ALA B 2 277 ? 86.950  82.835  72.561  1.00 336.28 ? 277 ALA B CB  1 
ATOM   5272  N N   . ILE B 2 278 ? 85.560  84.338  75.055  1.00 214.10 ? 278 ILE B N   1 
ATOM   5273  C CA  . ILE B 2 278 ? 85.505  85.166  76.261  1.00 220.30 ? 278 ILE B CA  1 
ATOM   5274  C C   . ILE B 2 278 ? 84.905  84.388  77.439  1.00 253.28 ? 278 ILE B C   1 
ATOM   5275  O O   . ILE B 2 278 ? 85.542  84.283  78.485  1.00 283.16 ? 278 ILE B O   1 
ATOM   5276  C CB  . ILE B 2 278 ? 84.712  86.469  75.979  1.00 235.45 ? 278 ILE B CB  1 
ATOM   5277  C CG1 . ILE B 2 278 ? 85.523  87.400  75.080  1.00 266.76 ? 278 ILE B CG1 1 
ATOM   5278  C CG2 . ILE B 2 278 ? 84.232  87.230  77.226  1.00 220.69 ? 278 ILE B CG2 1 
ATOM   5279  C CD1 . ILE B 2 278 ? 84.672  88.362  74.321  1.00 283.33 ? 278 ILE B CD1 1 
ATOM   5280  N N   . ILE B 2 279 ? 83.677  83.873  77.261  1.00 252.83 ? 279 ILE B N   1 
ATOM   5281  C CA  . ILE B 2 279 ? 82.872  83.301  78.334  1.00 254.78 ? 279 ILE B CA  1 
ATOM   5282  C C   . ILE B 2 279 ? 83.501  81.999  78.837  1.00 238.25 ? 279 ILE B C   1 
ATOM   5283  O O   . ILE B 2 279 ? 83.340  81.692  80.014  1.00 310.23 ? 279 ILE B O   1 
ATOM   5284  C CB  . ILE B 2 279 ? 81.402  83.145  77.875  1.00 312.84 ? 279 ILE B CB  1 
ATOM   5285  C CG1 . ILE B 2 279 ? 80.737  84.507  77.613  1.00 343.49 ? 279 ILE B CG1 1 
ATOM   5286  C CG2 . ILE B 2 279 ? 80.574  82.308  78.850  1.00 317.32 ? 279 ILE B CG2 1 
ATOM   5287  C CD1 . ILE B 2 279 ? 80.408  85.326  78.851  1.00 330.30 ? 279 ILE B CD1 1 
ATOM   5288  N N   . ILE B 2 280 ? 84.222  81.252  77.987  1.00 225.39 ? 280 ILE B N   1 
ATOM   5289  C CA  . ILE B 2 280 ? 85.019  80.117  78.452  1.00 282.82 ? 280 ILE B CA  1 
ATOM   5290  C C   . ILE B 2 280 ? 86.307  80.594  79.141  1.00 315.00 ? 280 ILE B C   1 
ATOM   5291  O O   . ILE B 2 280 ? 86.604  80.092  80.220  1.00 348.39 ? 280 ILE B O   1 
ATOM   5292  C CB  . ILE B 2 280 ? 85.282  79.106  77.316  1.00 323.42 ? 280 ILE B CB  1 
ATOM   5293  C CG1 . ILE B 2 280 ? 83.974  78.438  76.881  1.00 403.95 ? 280 ILE B CG1 1 
ATOM   5294  C CG2 . ILE B 2 280 ? 86.320  78.062  77.720  1.00 344.49 ? 280 ILE B CG2 1 
ATOM   5295  C CD1 . ILE B 2 280 ? 84.068  77.615  75.614  1.00 437.70 ? 280 ILE B CD1 1 
ATOM   5296  N N   . SER B 2 281 ? 87.066  81.539  78.556  1.00 278.53 ? 281 SER B N   1 
ATOM   5297  C CA  . SER B 2 281 ? 88.402  81.886  79.049  1.00 247.52 ? 281 SER B CA  1 
ATOM   5298  C C   . SER B 2 281 ? 88.402  82.626  80.391  1.00 234.66 ? 281 SER B C   1 
ATOM   5299  O O   . SER B 2 281 ? 89.242  82.313  81.225  1.00 252.28 ? 281 SER B O   1 
ATOM   5300  C CB  . SER B 2 281 ? 89.173  82.697  78.028  1.00 270.96 ? 281 SER B CB  1 
ATOM   5301  O OG  . SER B 2 281 ? 90.458  83.103  78.504  1.00 182.54 ? 281 SER B OG  1 
ATOM   5302  N N   . LEU B 2 282 ? 87.520  83.612  80.637  1.00 210.30 ? 282 LEU B N   1 
ATOM   5303  C CA  . LEU B 2 282 ? 87.706  84.445  81.829  1.00 227.37 ? 282 LEU B CA  1 
ATOM   5304  C C   . LEU B 2 282 ? 87.385  83.700  83.131  1.00 245.02 ? 282 LEU B C   1 
ATOM   5305  O O   . LEU B 2 282 ? 88.041  83.974  84.139  1.00 302.28 ? 282 LEU B O   1 
ATOM   5306  C CB  . LEU B 2 282 ? 86.952  85.773  81.686  1.00 171.77 ? 282 LEU B CB  1 
ATOM   5307  C CG  . LEU B 2 282 ? 87.638  86.743  80.727  1.00 229.17 ? 282 LEU B CG  1 
ATOM   5308  C CD1 . LEU B 2 282 ? 86.886  88.026  80.639  1.00 220.14 ? 282 LEU B CD1 1 
ATOM   5309  C CD2 . LEU B 2 282 ? 89.073  87.064  81.135  1.00 264.26 ? 282 LEU B CD2 1 
ATOM   5310  N N   . PRO B 2 283 ? 86.413  82.764  83.197  1.00 235.12 ? 283 PRO B N   1 
ATOM   5311  C CA  . PRO B 2 283 ? 86.385  81.772  84.278  1.00 249.81 ? 283 PRO B CA  1 
ATOM   5312  C C   . PRO B 2 283 ? 87.666  80.956  84.457  1.00 209.77 ? 283 PRO B C   1 
ATOM   5313  O O   . PRO B 2 283 ? 87.990  80.683  85.616  1.00 296.37 ? 283 PRO B O   1 
ATOM   5314  C CB  . PRO B 2 283 ? 85.182  80.893  83.920  1.00 314.31 ? 283 PRO B CB  1 
ATOM   5315  C CG  . PRO B 2 283 ? 84.288  81.843  83.167  1.00 349.64 ? 283 PRO B CG  1 
ATOM   5316  C CD  . PRO B 2 283 ? 85.253  82.636  82.312  1.00 288.08 ? 283 PRO B CD  1 
ATOM   5317  N N   . ILE B 2 284 ? 88.384  80.589  83.374  1.00 155.75 ? 284 ILE B N   1 
ATOM   5318  C CA  . ILE B 2 284 ? 89.669  79.895  83.525  1.00 215.18 ? 284 ILE B CA  1 
ATOM   5319  C C   . ILE B 2 284 ? 90.721  80.810  84.194  1.00 239.07 ? 284 ILE B C   1 
ATOM   5320  O O   . ILE B 2 284 ? 91.451  80.381  85.093  1.00 213.19 ? 284 ILE B O   1 
ATOM   5321  C CB  . ILE B 2 284 ? 90.146  79.262  82.192  1.00 209.56 ? 284 ILE B CB  1 
ATOM   5322  C CG1 . ILE B 2 284 ? 89.163  78.207  81.668  1.00 285.66 ? 284 ILE B CG1 1 
ATOM   5323  C CG2 . ILE B 2 284 ? 91.542  78.667  82.313  1.00 249.35 ? 284 ILE B CG2 1 
ATOM   5324  C CD1 . ILE B 2 284 ? 88.968  76.974  82.542  1.00 341.45 ? 284 ILE B CD1 1 
ATOM   5325  N N   . VAL B 2 285 ? 90.807  82.079  83.790  1.00 251.72 ? 285 VAL B N   1 
ATOM   5326  C CA  . VAL B 2 285 ? 91.682  83.028  84.471  1.00 223.88 ? 285 VAL B CA  1 
ATOM   5327  C C   . VAL B 2 285 ? 91.288  83.145  85.946  1.00 199.00 ? 285 VAL B C   1 
ATOM   5328  O O   . VAL B 2 285 ? 92.143  83.017  86.820  1.00 198.38 ? 285 VAL B O   1 
ATOM   5329  C CB  . VAL B 2 285 ? 91.660  84.411  83.794  1.00 241.36 ? 285 VAL B CB  1 
ATOM   5330  C CG1 . VAL B 2 285 ? 92.497  85.434  84.547  1.00 234.95 ? 285 VAL B CG1 1 
ATOM   5331  C CG2 . VAL B 2 285 ? 92.110  84.324  82.349  1.00 272.57 ? 285 VAL B CG2 1 
ATOM   5332  N N   . THR B 2 286 ? 89.999  83.392  86.220  1.00 181.93 ? 286 THR B N   1 
ATOM   5333  C CA  . THR B 2 286 ? 89.517  83.536  87.587  1.00 194.94 ? 286 THR B CA  1 
ATOM   5334  C C   . THR B 2 286 ? 89.876  82.315  88.439  1.00 186.32 ? 286 THR B C   1 
ATOM   5335  O O   . THR B 2 286 ? 90.240  82.475  89.606  1.00 188.49 ? 286 THR B O   1 
ATOM   5336  C CB  . THR B 2 286 ? 87.995  83.748  87.640  1.00 232.30 ? 286 THR B CB  1 
ATOM   5337  O OG1 . THR B 2 286 ? 87.659  84.832  86.779  1.00 191.18 ? 286 THR B OG1 1 
ATOM   5338  C CG2 . THR B 2 286 ? 87.456  84.043  89.028  1.00 193.27 ? 286 THR B CG2 1 
ATOM   5339  N N   . LEU B 2 287 ? 89.757  81.109  87.861  1.00 182.75 ? 287 LEU B N   1 
ATOM   5340  C CA  . LEU B 2 287 ? 90.121  79.881  88.543  1.00 213.19 ? 287 LEU B CA  1 
ATOM   5341  C C   . LEU B 2 287 ? 91.604  79.926  88.920  1.00 208.55 ? 287 LEU B C   1 
ATOM   5342  O O   . LEU B 2 287 ? 91.923  79.641  90.083  1.00 257.29 ? 287 LEU B O   1 
ATOM   5343  C CB  . LEU B 2 287 ? 89.775  78.680  87.652  1.00 294.55 ? 287 LEU B CB  1 
ATOM   5344  C CG  . LEU B 2 287 ? 90.217  77.311  88.174  1.00 375.45 ? 287 LEU B CG  1 
ATOM   5345  C CD1 . LEU B 2 287 ? 89.411  76.927  89.406  1.00 441.78 ? 287 LEU B CD1 1 
ATOM   5346  C CD2 . LEU B 2 287 ? 90.108  76.240  87.096  1.00 387.83 ? 287 LEU B CD2 1 
ATOM   5347  N N   . VAL B 2 288 ? 92.493  80.286  87.973  1.00 179.45 ? 288 VAL B N   1 
ATOM   5348  C CA  . VAL B 2 288 ? 93.930  80.320  88.238  1.00 209.25 ? 288 VAL B CA  1 
ATOM   5349  C C   . VAL B 2 288 ? 94.260  81.345  89.339  1.00 192.90 ? 288 VAL B C   1 
ATOM   5350  O O   . VAL B 2 288 ? 95.088  81.102  90.225  1.00 170.84 ? 288 VAL B O   1 
ATOM   5351  C CB  . VAL B 2 288 ? 94.728  80.592  86.946  1.00 211.02 ? 288 VAL B CB  1 
ATOM   5352  C CG1 . VAL B 2 288 ? 96.200  80.834  87.234  1.00 200.81 ? 288 VAL B CG1 1 
ATOM   5353  C CG2 . VAL B 2 288 ? 94.601  79.468  85.935  1.00 204.12 ? 288 VAL B CG2 1 
ATOM   5354  N N   . TYR B 2 289 ? 93.618  82.508  89.295  1.00 198.73 ? 289 TYR B N   1 
ATOM   5355  C CA  . TYR B 2 289 ? 93.850  83.541  90.296  1.00 227.69 ? 289 TYR B CA  1 
ATOM   5356  C C   . TYR B 2 289 ? 93.348  83.141  91.681  1.00 180.00 ? 289 TYR B C   1 
ATOM   5357  O O   . TYR B 2 289 ? 94.044  83.364  92.665  1.00 184.45 ? 289 TYR B O   1 
ATOM   5358  C CB  . TYR B 2 289 ? 93.214  84.826  89.779  1.00 211.52 ? 289 TYR B CB  1 
ATOM   5359  C CG  . TYR B 2 289 ? 93.973  85.524  88.661  1.00 190.83 ? 289 TYR B CG  1 
ATOM   5360  C CD1 . TYR B 2 289 ? 95.200  85.077  88.119  1.00 154.29 ? 289 TYR B CD1 1 
ATOM   5361  C CD2 . TYR B 2 289 ? 93.413  86.685  88.157  1.00 198.07 ? 289 TYR B CD2 1 
ATOM   5362  C CE1 . TYR B 2 289 ? 95.830  85.775  87.104  1.00 149.33 ? 289 TYR B CE1 1 
ATOM   5363  C CE2 . TYR B 2 289 ? 94.027  87.390  87.142  1.00 218.16 ? 289 TYR B CE2 1 
ATOM   5364  C CZ  . TYR B 2 289 ? 95.233  86.937  86.623  1.00 202.52 ? 289 TYR B CZ  1 
ATOM   5365  O OH  . TYR B 2 289 ? 95.765  87.709  85.633  1.00 193.38 ? 289 TYR B OH  1 
ATOM   5366  N N   . VAL B 2 290 ? 92.167  82.546  91.760  1.00 190.22 ? 290 VAL B N   1 
ATOM   5367  C CA  . VAL B 2 290 ? 91.712  82.027  93.034  1.00 187.04 ? 290 VAL B CA  1 
ATOM   5368  C C   . VAL B 2 290 ? 92.647  80.909  93.510  1.00 191.33 ? 290 VAL B C   1 
ATOM   5369  O O   . VAL B 2 290 ? 93.022  80.911  94.682  1.00 290.86 ? 290 VAL B O   1 
ATOM   5370  C CB  . VAL B 2 290 ? 90.240  81.602  92.951  1.00 240.80 ? 290 VAL B CB  1 
ATOM   5371  C CG1 . VAL B 2 290 ? 89.799  80.759  94.140  1.00 271.17 ? 290 VAL B CG1 1 
ATOM   5372  C CG2 . VAL B 2 290 ? 89.350  82.818  92.831  1.00 244.03 ? 290 VAL B CG2 1 
ATOM   5373  N N   . LEU B 2 291 ? 93.041  79.957  92.649  1.00 180.71 ? 291 LEU B N   1 
ATOM   5374  C CA  . LEU B 2 291 ? 93.914  78.858  93.076  1.00 202.63 ? 291 LEU B CA  1 
ATOM   5375  C C   . LEU B 2 291 ? 95.299  79.331  93.545  1.00 217.88 ? 291 LEU B C   1 
ATOM   5376  O O   . LEU B 2 291 ? 95.787  78.805  94.550  1.00 269.60 ? 291 LEU B O   1 
ATOM   5377  C CB  . LEU B 2 291 ? 94.041  77.836  91.949  1.00 217.97 ? 291 LEU B CB  1 
ATOM   5378  C CG  . LEU B 2 291 ? 92.800  76.977  91.722  1.00 299.44 ? 291 LEU B CG  1 
ATOM   5379  C CD1 . LEU B 2 291 ? 92.960  76.166  90.446  1.00 371.20 ? 291 LEU B CD1 1 
ATOM   5380  C CD2 . LEU B 2 291 ? 92.535  76.051  92.910  1.00 337.26 ? 291 LEU B CD2 1 
ATOM   5381  N N   . THR B 2 292 ? 95.927  80.310  92.870  1.00 165.55 ? 292 THR B N   1 
ATOM   5382  C CA  . THR B 2 292 ? 97.190  80.853  93.368  1.00 181.91 ? 292 THR B CA  1 
ATOM   5383  C C   . THR B 2 292 ? 97.034  81.530  94.727  1.00 213.32 ? 292 THR B C   1 
ATOM   5384  O O   . THR B 2 292 ? 97.912  81.379  95.573  1.00 298.03 ? 292 THR B O   1 
ATOM   5385  C CB  . THR B 2 292 ? 97.843  81.844  92.410  1.00 174.91 ? 292 THR B CB  1 
ATOM   5386  O OG1 . THR B 2 292 ? 96.846  82.715  91.888  1.00 226.94 ? 292 THR B OG1 1 
ATOM   5387  C CG2 . THR B 2 292 ? 98.508  81.115  91.278  1.00 230.12 ? 292 THR B CG2 1 
ATOM   5388  N N   . ASN B 2 293 ? 95.936  82.249  94.956  1.00 198.23 ? 293 ASN B N   1 
ATOM   5389  C CA  . ASN B 2 293 ? 95.713  82.847  96.264  1.00 183.52 ? 293 ASN B CA  1 
ATOM   5390  C C   . ASN B 2 293 ? 95.493  81.778  97.342  1.00 191.36 ? 293 ASN B C   1 
ATOM   5391  O O   . ASN B 2 293 ? 96.022  81.918  98.440  1.00 188.71 ? 293 ASN B O   1 
ATOM   5392  C CB  . ASN B 2 293 ? 94.601  83.883  96.193  1.00 191.31 ? 293 ASN B CB  1 
ATOM   5393  C CG  . ASN B 2 293 ? 95.141  85.171  95.628  1.00 180.89 ? 293 ASN B CG  1 
ATOM   5394  O OD1 . ASN B 2 293 ? 95.324  86.118  96.379  1.00 239.88 ? 293 ASN B OD1 1 
ATOM   5395  N ND2 . ASN B 2 293 ? 95.397  85.221  94.332  1.00 188.08 ? 293 ASN B ND2 1 
ATOM   5396  N N   . LEU B 2 294 ? 94.747  80.710  97.051  1.00 210.39 ? 294 LEU B N   1 
ATOM   5397  C CA  . LEU B 2 294 ? 94.667  79.577  97.967  1.00 207.20 ? 294 LEU B CA  1 
ATOM   5398  C C   . LEU B 2 294 ? 96.048  78.956  98.216  1.00 195.56 ? 294 LEU B C   1 
ATOM   5399  O O   . LEU B 2 294 ? 96.326  78.582  99.350  1.00 218.68 ? 294 LEU B O   1 
ATOM   5400  C CB  . LEU B 2 294 ? 93.689  78.540  97.409  1.00 241.36 ? 294 LEU B CB  1 
ATOM   5401  C CG  . LEU B 2 294 ? 92.226  78.962  97.461  1.00 289.05 ? 294 LEU B CG  1 
ATOM   5402  C CD1 . LEU B 2 294 ? 91.369  77.985  96.671  1.00 379.52 ? 294 LEU B CD1 1 
ATOM   5403  C CD2 . LEU B 2 294 ? 91.744  79.058  98.902  1.00 282.39 ? 294 LEU B CD2 1 
ATOM   5404  N N   . ALA B 2 295 ? 96.916  78.844  97.199  1.00 185.47 ? 295 ALA B N   1 
ATOM   5405  C CA  . ALA B 2 295 ? 98.269  78.343  97.410  1.00 200.33 ? 295 ALA B CA  1 
ATOM   5406  C C   . ALA B 2 295 ? 99.017  79.210  98.430  1.00 189.19 ? 295 ALA B C   1 
ATOM   5407  O O   . ALA B 2 295 ? 99.663  78.656  99.319  1.00 211.49 ? 295 ALA B O   1 
ATOM   5408  C CB  . ALA B 2 295 ? 99.004  78.226  96.096  1.00 231.12 ? 295 ALA B CB  1 
ATOM   5409  N N   . TYR B 2 296 ? 98.918  80.543  98.348  1.00 189.70 ? 296 TYR B N   1 
ATOM   5410  C CA  . TYR B 2 296 ? 99.479  81.404  99.384  1.00 186.17 ? 296 TYR B CA  1 
ATOM   5411  C C   . TYR B 2 296 ? 98.761  81.197  100.726 1.00 192.74 ? 296 TYR B C   1 
ATOM   5412  O O   . TYR B 2 296 ? 99.416  80.892  101.712 1.00 275.42 ? 296 TYR B O   1 
ATOM   5413  C CB  . TYR B 2 296 ? 99.435  82.889  99.014  1.00 242.54 ? 296 TYR B CB  1 
ATOM   5414  C CG  . TYR B 2 296 ? 100.076 83.247  97.684  1.00 251.64 ? 296 TYR B CG  1 
ATOM   5415  C CD1 . TYR B 2 296 ? 101.321 82.740  97.333  1.00 159.23 ? 296 TYR B CD1 1 
ATOM   5416  C CD2 . TYR B 2 296 ? 99.426  84.092  96.781  1.00 269.95 ? 296 TYR B CD2 1 
ATOM   5417  C CE1 . TYR B 2 296 ? 101.908 83.060  96.120  1.00 163.04 ? 296 TYR B CE1 1 
ATOM   5418  C CE2 . TYR B 2 296 ? 100.000 84.421  95.566  1.00 264.42 ? 296 TYR B CE2 1 
ATOM   5419  C CZ  . TYR B 2 296 ? 101.244 83.903  95.233  1.00 240.19 ? 296 TYR B CZ  1 
ATOM   5420  O OH  . TYR B 2 296 ? 101.756 84.266  94.016  1.00 251.55 ? 296 TYR B OH  1 
ATOM   5421  N N   . PHE B 2 297 ? 97.436  81.341  100.802 1.00 145.59 ? 297 PHE B N   1 
ATOM   5422  C CA  . PHE B 2 297 ? 96.746  81.275  102.091 1.00 218.49 ? 297 PHE B CA  1 
ATOM   5423  C C   . PHE B 2 297 ? 96.834  79.921  102.828 1.00 215.58 ? 297 PHE B C   1 
ATOM   5424  O O   . PHE B 2 297 ? 96.631  79.871  104.042 1.00 186.11 ? 297 PHE B O   1 
ATOM   5425  C CB  . PHE B 2 297 ? 95.275  81.654  101.913 1.00 262.46 ? 297 PHE B CB  1 
ATOM   5426  C CG  . PHE B 2 297 ? 95.011  83.032  101.370 1.00 210.68 ? 297 PHE B CG  1 
ATOM   5427  C CD1 . PHE B 2 297 ? 95.752  84.119  101.798 1.00 175.94 ? 297 PHE B CD1 1 
ATOM   5428  C CD2 . PHE B 2 297 ? 93.997  83.240  100.440 1.00 261.24 ? 297 PHE B CD2 1 
ATOM   5429  C CE1 . PHE B 2 297 ? 95.485  85.382  101.292 1.00 250.41 ? 297 PHE B CE1 1 
ATOM   5430  C CE2 . PHE B 2 297 ? 93.737  84.507  99.940  1.00 280.59 ? 297 PHE B CE2 1 
ATOM   5431  C CZ  . PHE B 2 297 ? 94.487  85.573  100.365 1.00 295.91 ? 297 PHE B CZ  1 
ATOM   5432  N N   . THR B 2 298 ? 97.128  78.825  102.119 1.00 212.96 ? 298 THR B N   1 
ATOM   5433  C CA  . THR B 2 298 ? 97.351  77.525  102.736 1.00 252.78 ? 298 THR B CA  1 
ATOM   5434  C C   . THR B 2 298 ? 98.817  77.329  103.141 1.00 254.47 ? 298 THR B C   1 
ATOM   5435  O O   . THR B 2 298 ? 99.148  76.260  103.656 1.00 343.69 ? 298 THR B O   1 
ATOM   5436  C CB  . THR B 2 298 ? 96.864  76.399  101.811 1.00 314.37 ? 298 THR B CB  1 
ATOM   5437  O OG1 . THR B 2 298 ? 97.536  76.489  100.552 1.00 347.16 ? 298 THR B OG1 1 
ATOM   5438  C CG2 . THR B 2 298 ? 95.361  76.443  101.618 1.00 323.85 ? 298 THR B CG2 1 
ATOM   5439  N N   . THR B 2 299 ? 99.685  78.337  102.926 1.00 169.97 ? 299 THR B N   1 
ATOM   5440  C CA  . THR B 2 299 ? 101.105 78.262  103.268 1.00 231.33 ? 299 THR B CA  1 
ATOM   5441  C C   . THR B 2 299 ? 101.591 79.421  104.155 1.00 241.71 ? 299 THR B C   1 
ATOM   5442  O O   . THR B 2 299 ? 102.523 79.231  104.941 1.00 257.02 ? 299 THR B O   1 
ATOM   5443  C CB  . THR B 2 299 ? 101.939 78.206  101.978 1.00 250.49 ? 299 THR B CB  1 
ATOM   5444  O OG1 . THR B 2 299 ? 101.367 77.240  101.087 1.00 205.37 ? 299 THR B OG1 1 
ATOM   5445  C CG2 . THR B 2 299 ? 103.401 77.891  102.220 1.00 185.30 ? 299 THR B CG2 1 
ATOM   5446  N N   . LEU B 2 300 ? 100.977 80.615  104.035 1.00 235.84 ? 300 LEU B N   1 
ATOM   5447  C CA  . LEU B 2 300 ? 101.468 81.852  104.638 1.00 243.49 ? 300 LEU B CA  1 
ATOM   5448  C C   . LEU B 2 300 ? 100.382 82.498  105.504 1.00 229.80 ? 300 LEU B C   1 
ATOM   5449  O O   . LEU B 2 300 ? 99.188  82.382  105.257 1.00 222.14 ? 300 LEU B O   1 
ATOM   5450  C CB  . LEU B 2 300 ? 101.897 82.844  103.543 1.00 236.75 ? 300 LEU B CB  1 
ATOM   5451  C CG  . LEU B 2 300 ? 102.980 82.394  102.559 1.00 231.91 ? 300 LEU B CG  1 
ATOM   5452  C CD1 . LEU B 2 300 ? 103.223 83.506  101.547 1.00 187.24 ? 300 LEU B CD1 1 
ATOM   5453  C CD2 . LEU B 2 300 ? 104.279 82.000  103.252 1.00 234.51 ? 300 LEU B CD2 1 
ATOM   5454  N N   . SER B 2 301 ? 100.834 83.200  106.542 1.00 235.82 ? 301 SER B N   1 
ATOM   5455  C CA  . SER B 2 301 ? 99.975  83.998  107.403 1.00 228.41 ? 301 SER B CA  1 
ATOM   5456  C C   . SER B 2 301 ? 99.656  85.342  106.754 1.00 179.23 ? 301 SER B C   1 
ATOM   5457  O O   . SER B 2 301 ? 100.505 85.879  106.039 1.00 232.57 ? 301 SER B O   1 
ATOM   5458  C CB  . SER B 2 301 ? 100.657 84.204  108.732 1.00 269.16 ? 301 SER B CB  1 
ATOM   5459  O OG  . SER B 2 301 ? 99.865  85.032  109.531 1.00 316.17 ? 301 SER B OG  1 
ATOM   5460  N N   . THR B 2 302 ? 98.462  85.907  107.023 1.00 176.03 ? 302 THR B N   1 
ATOM   5461  C CA  . THR B 2 302 ? 98.163  87.311  106.718 1.00 232.35 ? 302 THR B CA  1 
ATOM   5462  C C   . THR B 2 302 ? 99.304  88.253  107.156 1.00 213.95 ? 302 THR B C   1 
ATOM   5463  O O   . THR B 2 302 ? 99.705  89.159  106.454 1.00 176.97 ? 302 THR B O   1 
ATOM   5464  C CB  . THR B 2 302 ? 96.844  87.780  107.362 1.00 248.27 ? 302 THR B CB  1 
ATOM   5465  O OG1 . THR B 2 302 ? 95.825  86.819  107.084 1.00 197.57 ? 302 THR B OG1 1 
ATOM   5466  C CG2 . THR B 2 302 ? 96.420  89.161  106.892 1.00 247.52 ? 302 THR B CG2 1 
ATOM   5467  N N   . GLU B 2 303 ? 99.855  88.054  108.343 1.00 210.17 ? 303 GLU B N   1 
ATOM   5468  C CA  . GLU B 2 303 ? 100.903 88.903  108.879 1.00 237.54 ? 303 GLU B CA  1 
ATOM   5469  C C   . GLU B 2 303 ? 102.253 88.715  108.181 1.00 252.71 ? 303 GLU B C   1 
ATOM   5470  O O   . GLU B 2 303 ? 103.133 89.546  108.394 1.00 301.68 ? 303 GLU B O   1 
ATOM   5471  C CB  . GLU B 2 303 ? 101.103 88.585  110.360 1.00 369.92 ? 303 GLU B CB  1 
ATOM   5472  C CG  . GLU B 2 303 ? 99.869  88.793  111.248 1.00 482.36 ? 303 GLU B CG  1 
ATOM   5473  C CD  . GLU B 2 303 ? 99.862  87.854  112.450 1.00 564.97 ? 303 GLU B CD  1 
ATOM   5474  O OE1 . GLU B 2 303 ? 101.003 87.459  112.742 1.00 593.70 ? 303 GLU B OE1 1 
ATOM   5475  O OE2 . GLU B 2 303 ? 98.766  87.452  112.987 1.00 579.04 ? 303 GLU B OE2 1 
ATOM   5476  N N   . GLN B 2 304 ? 102.425 87.645  107.377 1.00 218.96 ? 304 GLN B N   1 
ATOM   5477  C CA  . GLN B 2 304 ? 103.558 87.511  106.472 1.00 190.75 ? 304 GLN B CA  1 
ATOM   5478  C C   . GLN B 2 304 ? 103.249 88.200  105.144 1.00 205.85 ? 304 GLN B C   1 
ATOM   5479  O O   . GLN B 2 304 ? 104.046 89.000  104.683 1.00 228.67 ? 304 GLN B O   1 
ATOM   5480  C CB  . GLN B 2 304 ? 103.900 86.045  106.227 1.00 208.22 ? 304 GLN B CB  1 
ATOM   5481  C CG  . GLN B 2 304 ? 104.480 85.335  107.431 1.00 240.12 ? 304 GLN B CG  1 
ATOM   5482  C CD  . GLN B 2 304 ? 104.646 83.858  107.152 1.00 288.06 ? 304 GLN B CD  1 
ATOM   5483  O OE1 . GLN B 2 304 ? 103.672 83.110  107.201 1.00 289.22 ? 304 GLN B OE1 1 
ATOM   5484  N NE2 . GLN B 2 304 ? 105.868 83.419  106.866 1.00 287.16 ? 304 GLN B NE2 1 
ATOM   5485  N N   . MET B 2 305 ? 102.099 87.899  104.534 1.00 230.04 ? 305 MET B N   1 
ATOM   5486  C CA  . MET B 2 305 ? 101.770 88.352  103.190 1.00 201.42 ? 305 MET B CA  1 
ATOM   5487  C C   . MET B 2 305 ? 101.652 89.872  103.079 1.00 197.71 ? 305 MET B C   1 
ATOM   5488  O O   . MET B 2 305 ? 101.849 90.401  101.988 1.00 301.54 ? 305 MET B O   1 
ATOM   5489  C CB  . MET B 2 305 ? 100.431 87.756  102.746 1.00 205.58 ? 305 MET B CB  1 
ATOM   5490  C CG  . MET B 2 305 ? 100.508 86.272  102.414 1.00 185.05 ? 305 MET B CG  1 
ATOM   5491  S SD  . MET B 2 305 ? 98.947  85.660  101.737 1.00 237.73 ? 305 MET B SD  1 
ATOM   5492  C CE  . MET B 2 305 ? 98.846  86.480  100.142 1.00 223.53 ? 305 MET B CE  1 
ATOM   5493  N N   . LEU B 2 306 ? 101.318 90.575  104.172 1.00 163.89 ? 306 LEU B N   1 
ATOM   5494  C CA  . LEU B 2 306 ? 101.297 92.036  104.155 1.00 232.31 ? 306 LEU B CA  1 
ATOM   5495  C C   . LEU B 2 306 ? 102.696 92.653  104.345 1.00 230.14 ? 306 LEU B C   1 
ATOM   5496  O O   . LEU B 2 306 ? 102.879 93.838  104.057 1.00 198.74 ? 306 LEU B O   1 
ATOM   5497  C CB  . LEU B 2 306 ? 100.308 92.528  105.221 1.00 257.52 ? 306 LEU B CB  1 
ATOM   5498  C CG  . LEU B 2 306 ? 98.848  92.120  104.998 1.00 246.12 ? 306 LEU B CG  1 
ATOM   5499  C CD1 . LEU B 2 306 ? 97.928  92.757  106.041 1.00 306.48 ? 306 LEU B CD1 1 
ATOM   5500  C CD2 . LEU B 2 306 ? 98.381  92.467  103.597 1.00 190.74 ? 306 LEU B CD2 1 
ATOM   5501  N N   . SER B 2 307 ? 103.680 91.870  104.811 1.00 213.14 ? 307 SER B N   1 
ATOM   5502  C CA  . SER B 2 307 ? 105.013 92.372  105.124 1.00 282.66 ? 307 SER B CA  1 
ATOM   5503  C C   . SER B 2 307 ? 105.949 92.335  103.915 1.00 284.76 ? 307 SER B C   1 
ATOM   5504  O O   . SER B 2 307 ? 106.906 93.105  103.894 1.00 365.47 ? 307 SER B O   1 
ATOM   5505  C CB  . SER B 2 307 ? 105.636 91.613  106.288 1.00 340.85 ? 307 SER B CB  1 
ATOM   5506  O OG  . SER B 2 307 ? 106.100 90.324  105.908 1.00 335.93 ? 307 SER B OG  1 
ATOM   5507  N N   . SER B 2 308 ? 105.680 91.444  102.940 1.00 246.40 ? 308 SER B N   1 
ATOM   5508  C CA  . SER B 2 308 ? 106.589 91.134  101.843 1.00 264.78 ? 308 SER B CA  1 
ATOM   5509  C C   . SER B 2 308 ? 106.140 91.810  100.550 1.00 244.72 ? 308 SER B C   1 
ATOM   5510  O O   . SER B 2 308 ? 105.012 91.608  100.132 1.00 259.67 ? 308 SER B O   1 
ATOM   5511  C CB  . SER B 2 308 ? 106.703 89.641  101.624 1.00 209.32 ? 308 SER B CB  1 
ATOM   5512  O OG  . SER B 2 308 ? 107.711 89.357  100.659 1.00 169.30 ? 308 SER B OG  1 
ATOM   5513  N N   . GLU B 2 309 ? 107.046 92.574  99.920  1.00 216.64 ? 309 GLU B N   1 
ATOM   5514  C CA  . GLU B 2 309 ? 106.816 93.195  98.625  1.00 243.60 ? 309 GLU B CA  1 
ATOM   5515  C C   . GLU B 2 309 ? 106.796 92.175  97.468  1.00 265.75 ? 309 GLU B C   1 
ATOM   5516  O O   . GLU B 2 309 ? 106.427 92.562  96.358  1.00 266.10 ? 309 GLU B O   1 
ATOM   5517  C CB  . GLU B 2 309 ? 107.858 94.297  98.385  1.00 309.76 ? 309 GLU B CB  1 
ATOM   5518  C CG  . GLU B 2 309 ? 109.323 93.853  98.465  1.00 319.25 ? 309 GLU B CG  1 
ATOM   5519  C CD  . GLU B 2 309 ? 110.003 93.851  99.831  1.00 328.93 ? 309 GLU B CD  1 
ATOM   5520  O OE1 . GLU B 2 309 ? 109.322 94.096  100.834 1.00 429.93 ? 309 GLU B OE1 1 
ATOM   5521  O OE2 . GLU B 2 309 ? 111.220 93.588  99.898  1.00 316.46 ? 309 GLU B OE2 1 
ATOM   5522  N N   . ALA B 2 310 ? 107.177 90.896  97.701  1.00 235.80 ? 310 ALA B N   1 
ATOM   5523  C CA  . ALA B 2 310 ? 107.315 89.891  96.654  1.00 177.17 ? 310 ALA B CA  1 
ATOM   5524  C C   . ALA B 2 310 ? 106.833 88.509  97.139  1.00 166.47 ? 310 ALA B C   1 
ATOM   5525  O O   . ALA B 2 310 ? 107.633 87.573  97.295  1.00 101.04 ? 310 ALA B O   1 
ATOM   5526  C CB  . ALA B 2 310 ? 108.768 89.913  96.216  1.00 131.96 ? 310 ALA B CB  1 
ATOM   5527  N N   . VAL B 2 311 ? 105.505 88.384  97.349  1.00 161.17 ? 311 VAL B N   1 
ATOM   5528  C CA  . VAL B 2 311 ? 104.918 87.336  98.193  1.00 184.05 ? 311 VAL B CA  1 
ATOM   5529  C C   . VAL B 2 311 ? 105.237 85.907  97.705  1.00 129.38 ? 311 VAL B C   1 
ATOM   5530  O O   . VAL B 2 311 ? 105.426 84.997  98.501  1.00 136.90 ? 311 VAL B O   1 
ATOM   5531  C CB  . VAL B 2 311 ? 103.403 87.557  98.378  1.00 174.86 ? 311 VAL B CB  1 
ATOM   5532  C CG1 . VAL B 2 311 ? 102.607 87.306  97.119  1.00 194.30 ? 311 VAL B CG1 1 
ATOM   5533  C CG2 . VAL B 2 311 ? 102.852 86.695  99.506  1.00 232.01 ? 311 VAL B CG2 1 
ATOM   5534  N N   . ALA B 2 312 ? 105.325 85.702  96.407  1.00 133.16 ? 312 ALA B N   1 
ATOM   5535  C CA  . ALA B 2 312 ? 105.640 84.386  95.882  1.00 168.45 ? 312 ALA B CA  1 
ATOM   5536  C C   . ALA B 2 312 ? 107.067 83.941  96.219  1.00 152.30 ? 312 ALA B C   1 
ATOM   5537  O O   . ALA B 2 312 ? 107.314 82.741  96.209  1.00 228.77 ? 312 ALA B O   1 
ATOM   5538  C CB  . ALA B 2 312 ? 105.370 84.357  94.393  1.00 191.79 ? 312 ALA B CB  1 
ATOM   5539  N N   . VAL B 2 313 ? 108.000 84.856  96.512  1.00 145.97 ? 313 VAL B N   1 
ATOM   5540  C CA  . VAL B 2 313 ? 109.329 84.461  96.948  1.00 153.74 ? 313 VAL B CA  1 
ATOM   5541  C C   . VAL B 2 313 ? 109.239 83.943  98.386  1.00 184.04 ? 313 VAL B C   1 
ATOM   5542  O O   . VAL B 2 313 ? 109.964 83.000  98.695  1.00 248.23 ? 313 VAL B O   1 
ATOM   5543  C CB  . VAL B 2 313 ? 110.358 85.601  96.799  1.00 186.45 ? 313 VAL B CB  1 
ATOM   5544  C CG1 . VAL B 2 313 ? 111.755 85.250  97.294  1.00 191.43 ? 313 VAL B CG1 1 
ATOM   5545  C CG2 . VAL B 2 313 ? 110.452 86.036  95.358  1.00 194.29 ? 313 VAL B CG2 1 
ATOM   5546  N N   . ASP B 2 314 ? 108.387 84.519  99.264  1.00 185.00 ? 314 ASP B N   1 
ATOM   5547  C CA  . ASP B 2 314 ? 108.169 83.960  100.603 1.00 248.45 ? 314 ASP B CA  1 
ATOM   5548  C C   . ASP B 2 314 ? 107.693 82.499  100.529 1.00 230.27 ? 314 ASP B C   1 
ATOM   5549  O O   . ASP B 2 314 ? 108.244 81.608  101.194 1.00 240.32 ? 314 ASP B O   1 
ATOM   5550  C CB  . ASP B 2 314 ? 107.167 84.780  101.435 1.00 298.24 ? 314 ASP B CB  1 
ATOM   5551  C CG  . ASP B 2 314 ? 107.627 86.163  101.875 1.00 311.32 ? 314 ASP B CG  1 
ATOM   5552  O OD1 . ASP B 2 314 ? 108.338 86.832  101.092 1.00 290.33 ? 314 ASP B OD1 1 
ATOM   5553  O OD2 . ASP B 2 314 ? 107.258 86.576  103.004 1.00 300.91 ? 314 ASP B OD2 1 
ATOM   5554  N N   . PHE B 2 315 ? 106.657 82.276  99.713  1.00 187.01 ? 315 PHE B N   1 
ATOM   5555  C CA  . PHE B 2 315 ? 106.102 80.956  99.439  1.00 177.49 ? 315 PHE B CA  1 
ATOM   5556  C C   . PHE B 2 315 ? 107.167 80.013  98.852  1.00 153.92 ? 315 PHE B C   1 
ATOM   5557  O O   . PHE B 2 315 ? 107.297 78.881  99.288  1.00 205.93 ? 315 PHE B O   1 
ATOM   5558  C CB  . PHE B 2 315 ? 104.886 81.167  98.541  1.00 189.91 ? 315 PHE B CB  1 
ATOM   5559  C CG  . PHE B 2 315 ? 104.254 79.944  97.937  1.00 190.60 ? 315 PHE B CG  1 
ATOM   5560  C CD1 . PHE B 2 315 ? 104.768 79.370  96.778  1.00 227.62 ? 315 PHE B CD1 1 
ATOM   5561  C CD2 . PHE B 2 315 ? 103.133 79.389  98.520  1.00 161.11 ? 315 PHE B CD2 1 
ATOM   5562  C CE1 . PHE B 2 315 ? 104.176 78.255  96.216  1.00 246.37 ? 315 PHE B CE1 1 
ATOM   5563  C CE2 . PHE B 2 315 ? 102.548 78.267  97.964  1.00 192.46 ? 315 PHE B CE2 1 
ATOM   5564  C CZ  . PHE B 2 315 ? 103.067 77.705  96.820  1.00 252.36 ? 315 PHE B CZ  1 
ATOM   5565  N N   . GLY B 2 316 ? 107.949 80.474  97.880  1.00 169.30 ? 316 GLY B N   1 
ATOM   5566  C CA  . GLY B 2 316 ? 109.038 79.692  97.317  1.00 224.05 ? 316 GLY B CA  1 
ATOM   5567  C C   . GLY B 2 316 ? 110.150 79.365  98.314  1.00 276.63 ? 316 GLY B C   1 
ATOM   5568  O O   . GLY B 2 316 ? 110.699 78.269  98.257  1.00 343.74 ? 316 GLY B O   1 
ATOM   5569  N N   . ASN B 2 317 ? 110.469 80.303  99.219  1.00 268.46 ? 317 ASN B N   1 
ATOM   5570  C CA  . ASN B 2 317 ? 111.441 80.086  100.285 1.00 290.52 ? 317 ASN B CA  1 
ATOM   5571  C C   . ASN B 2 317 ? 110.966 79.035  101.302 1.00 297.80 ? 317 ASN B C   1 
ATOM   5572  O O   . ASN B 2 317 ? 111.806 78.349  101.895 1.00 300.03 ? 317 ASN B O   1 
ATOM   5573  C CB  . ASN B 2 317 ? 111.780 81.396  101.011 1.00 303.68 ? 317 ASN B CB  1 
ATOM   5574  C CG  . ASN B 2 317 ? 112.597 82.398  100.210 1.00 347.63 ? 317 ASN B CG  1 
ATOM   5575  O OD1 . ASN B 2 317 ? 113.001 82.153  99.073  1.00 298.81 ? 317 ASN B OD1 1 
ATOM   5576  N ND2 . ASN B 2 317 ? 112.857 83.551  100.806 1.00 383.82 ? 317 ASN B ND2 1 
ATOM   5577  N N   . TYR B 2 318 ? 109.643 78.904  101.513 1.00 276.52 ? 318 TYR B N   1 
ATOM   5578  C CA  . TYR B 2 318 ? 109.088 77.895  102.415 1.00 282.69 ? 318 TYR B CA  1 
ATOM   5579  C C   . TYR B 2 318 ? 109.238 76.474  101.844 1.00 253.13 ? 318 TYR B C   1 
ATOM   5580  O O   . TYR B 2 318 ? 109.791 75.611  102.524 1.00 253.39 ? 318 TYR B O   1 
ATOM   5581  C CB  . TYR B 2 318 ? 107.631 78.247  102.739 1.00 303.64 ? 318 TYR B CB  1 
ATOM   5582  C CG  . TYR B 2 318 ? 106.998 77.295  103.738 1.00 306.92 ? 318 TYR B CG  1 
ATOM   5583  C CD1 . TYR B 2 318 ? 106.419 76.090  103.348 1.00 297.87 ? 318 TYR B CD1 1 
ATOM   5584  C CD2 . TYR B 2 318 ? 106.975 77.609  105.083 1.00 367.26 ? 318 TYR B CD2 1 
ATOM   5585  C CE1 . TYR B 2 318 ? 105.849 75.223  104.269 1.00 356.22 ? 318 TYR B CE1 1 
ATOM   5586  C CE2 . TYR B 2 318 ? 106.399 76.759  106.020 1.00 390.19 ? 318 TYR B CE2 1 
ATOM   5587  C CZ  . TYR B 2 318 ? 105.833 75.561  105.612 1.00 388.60 ? 318 TYR B CZ  1 
ATOM   5588  O OH  . TYR B 2 318 ? 105.267 74.714  106.524 1.00 439.48 ? 318 TYR B OH  1 
ATOM   5589  N N   . HIS B 2 319 ? 108.759 76.226  100.609 1.00 230.12 ? 319 HIS B N   1 
ATOM   5590  C CA  . HIS B 2 319 ? 108.642 74.881  100.047 1.00 220.12 ? 319 HIS B CA  1 
ATOM   5591  C C   . HIS B 2 319 ? 109.929 74.311  99.438  1.00 272.07 ? 319 HIS B C   1 
ATOM   5592  O O   . HIS B 2 319 ? 110.183 73.118  99.604  1.00 276.11 ? 319 HIS B O   1 
ATOM   5593  C CB  . HIS B 2 319 ? 107.528 74.838  98.991  1.00 240.14 ? 319 HIS B CB  1 
ATOM   5594  C CG  . HIS B 2 319 ? 106.156 74.780  99.582  1.00 270.63 ? 319 HIS B CG  1 
ATOM   5595  N ND1 . HIS B 2 319 ? 105.079 75.572  99.245  1.00 227.56 ? 319 HIS B ND1 1 
ATOM   5596  C CD2 . HIS B 2 319 ? 105.707 73.952  100.535 1.00 301.77 ? 319 HIS B CD2 1 
ATOM   5597  C CE1 . HIS B 2 319 ? 104.030 75.222  99.977  1.00 217.17 ? 319 HIS B CE1 1 
ATOM   5598  N NE2 . HIS B 2 319 ? 104.387 74.242  100.770 1.00 274.81 ? 319 HIS B NE2 1 
ATOM   5599  N N   . LEU B 2 320 ? 110.738 75.112  98.727  1.00 302.90 ? 320 LEU B N   1 
ATOM   5600  C CA  . LEU B 2 320 ? 111.576 74.543  97.670  1.00 286.60 ? 320 LEU B CA  1 
ATOM   5601  C C   . LEU B 2 320 ? 112.989 74.173  98.124  1.00 262.45 ? 320 LEU B C   1 
ATOM   5602  O O   . LEU B 2 320 ? 113.525 73.198  97.595  1.00 256.25 ? 320 LEU B O   1 
ATOM   5603  C CB  . LEU B 2 320 ? 111.630 75.511  96.486  1.00 279.81 ? 320 LEU B CB  1 
ATOM   5604  C CG  . LEU B 2 320 ? 110.299 75.706  95.760  1.00 316.05 ? 320 LEU B CG  1 
ATOM   5605  C CD1 . LEU B 2 320 ? 110.410 76.823  94.738  1.00 373.62 ? 320 LEU B CD1 1 
ATOM   5606  C CD2 . LEU B 2 320 ? 109.841 74.417  95.090  1.00 306.93 ? 320 LEU B CD2 1 
ATOM   5607  N N   . GLY B 2 321 ? 113.607 74.922  99.053  1.00 254.33 ? 321 GLY B N   1 
ATOM   5608  C CA  . GLY B 2 321 ? 115.007 74.699  99.421  1.00 295.04 ? 321 GLY B CA  1 
ATOM   5609  C C   . GLY B 2 321 ? 116.018 75.164  98.358  1.00 336.18 ? 321 GLY B C   1 
ATOM   5610  O O   . GLY B 2 321 ? 117.005 75.821  98.685  1.00 248.45 ? 321 GLY B O   1 
ATOM   5611  N N   . VAL B 2 322 ? 115.771 74.823  97.077  1.00 371.31 ? 322 VAL B N   1 
ATOM   5612  C CA  . VAL B 2 322 ? 116.427 75.397  95.894  1.00 359.99 ? 322 VAL B CA  1 
ATOM   5613  C C   . VAL B 2 322 ? 115.825 76.764  95.492  1.00 376.93 ? 322 VAL B C   1 
ATOM   5614  O O   . VAL B 2 322 ? 116.067 77.248  94.379  1.00 356.45 ? 322 VAL B O   1 
ATOM   5615  C CB  . VAL B 2 322 ? 116.379 74.348  94.751  1.00 312.63 ? 322 VAL B CB  1 
ATOM   5616  C CG1 . VAL B 2 322 ? 114.965 74.151  94.174  1.00 278.58 ? 322 VAL B CG1 1 
ATOM   5617  C CG2 . VAL B 2 322 ? 117.407 74.603  93.642  1.00 279.99 ? 322 VAL B CG2 1 
ATOM   5618  N N   . MET B 2 323 ? 115.066 77.402  96.407  1.00 354.89 ? 323 MET B N   1 
ATOM   5619  C CA  . MET B 2 323 ? 114.195 78.566  96.203  1.00 247.30 ? 323 MET B CA  1 
ATOM   5620  C C   . MET B 2 323 ? 114.781 79.617  95.244  1.00 183.94 ? 323 MET B C   1 
ATOM   5621  O O   . MET B 2 323 ? 114.060 80.086  94.379  1.00 158.24 ? 323 MET B O   1 
ATOM   5622  C CB  . MET B 2 323 ? 113.886 79.222  97.568  1.00 285.71 ? 323 MET B CB  1 
ATOM   5623  C CG  . MET B 2 323 ? 115.146 79.682  98.355  1.00 408.24 ? 323 MET B CG  1 
ATOM   5624  S SD  . MET B 2 323 ? 115.001 79.910  100.152 1.00 464.19 ? 323 MET B SD  1 
ATOM   5625  C CE  . MET B 2 323 ? 115.063 78.214  100.721 1.00 465.71 ? 323 MET B CE  1 
ATOM   5626  N N   . SER B 2 324 ? 116.072 79.991  95.376  1.00 249.06 ? 324 SER B N   1 
ATOM   5627  C CA  . SER B 2 324 ? 116.665 81.126  94.662  1.00 339.24 ? 324 SER B CA  1 
ATOM   5628  C C   . SER B 2 324 ? 116.602 80.965  93.141  1.00 285.69 ? 324 SER B C   1 
ATOM   5629  O O   . SER B 2 324 ? 116.465 81.963  92.421  1.00 310.14 ? 324 SER B O   1 
ATOM   5630  C CB  . SER B 2 324 ? 118.103 81.395  95.096  1.00 354.36 ? 324 SER B CB  1 
ATOM   5631  O OG  . SER B 2 324 ? 118.571 82.641  94.562  1.00 262.55 ? 324 SER B OG  1 
ATOM   5632  N N   . TRP B 2 325 ? 116.703 79.716  92.666  1.00 235.55 ? 325 TRP B N   1 
ATOM   5633  C CA  . TRP B 2 325 ? 116.781 79.416  91.239  1.00 292.29 ? 325 TRP B CA  1 
ATOM   5634  C C   . TRP B 2 325 ? 115.414 79.155  90.592  1.00 276.19 ? 325 TRP B C   1 
ATOM   5635  O O   . TRP B 2 325 ? 115.378 78.865  89.392  1.00 312.01 ? 325 TRP B O   1 
ATOM   5636  C CB  . TRP B 2 325 ? 117.747 78.236  91.038  1.00 285.66 ? 325 TRP B CB  1 
ATOM   5637  C CG  . TRP B 2 325 ? 119.168 78.614  91.365  1.00 321.26 ? 325 TRP B CG  1 
ATOM   5638  C CD1 . TRP B 2 325 ? 119.843 78.348  92.523  1.00 325.47 ? 325 TRP B CD1 1 
ATOM   5639  C CD2 . TRP B 2 325 ? 120.094 79.341  90.516  1.00 366.83 ? 325 TRP B CD2 1 
ATOM   5640  N NE1 . TRP B 2 325 ? 121.116 78.854  92.457  1.00 352.06 ? 325 TRP B NE1 1 
ATOM   5641  C CE2 . TRP B 2 325 ? 121.306 79.468  91.242  1.00 387.03 ? 325 TRP B CE2 1 
ATOM   5642  C CE3 . TRP B 2 325 ? 120.030 79.896  89.222  1.00 313.14 ? 325 TRP B CE3 1 
ATOM   5643  C CZ2 . TRP B 2 325 ? 122.428 80.124  90.714  1.00 359.83 ? 325 TRP B CZ2 1 
ATOM   5644  C CZ3 . TRP B 2 325 ? 121.137 80.543  88.701  1.00 286.44 ? 325 TRP B CZ3 1 
ATOM   5645  C CH2 . TRP B 2 325 ? 122.322 80.655  89.441  1.00 321.00 ? 325 TRP B CH2 1 
ATOM   5646  N N   . ILE B 2 326 ? 114.306 79.266  91.355  1.00 195.22 ? 326 ILE B N   1 
ATOM   5647  C CA  . ILE B 2 326 ? 112.988 78.907  90.846  1.00 253.22 ? 326 ILE B CA  1 
ATOM   5648  C C   . ILE B 2 326 ? 112.078 80.144  90.825  1.00 248.55 ? 326 ILE B C   1 
ATOM   5649  O O   . ILE B 2 326 ? 112.014 80.804  89.786  1.00 318.76 ? 326 ILE B O   1 
ATOM   5650  C CB  . ILE B 2 326 ? 112.414 77.696  91.613  1.00 294.21 ? 326 ILE B CB  1 
ATOM   5651  C CG1 . ILE B 2 326 ? 113.357 76.482  91.584  1.00 391.61 ? 326 ILE B CG1 1 
ATOM   5652  C CG2 . ILE B 2 326 ? 111.040 77.330  91.083  1.00 280.54 ? 326 ILE B CG2 1 
ATOM   5653  C CD1 . ILE B 2 326 ? 113.587 75.869  90.199  1.00 421.11 ? 326 ILE B CD1 1 
ATOM   5654  N N   . ILE B 2 327 ? 111.371 80.481  91.923  1.00 162.88 ? 327 ILE B N   1 
ATOM   5655  C CA  . ILE B 2 327 ? 110.293 81.460  91.811  1.00 195.31 ? 327 ILE B CA  1 
ATOM   5656  C C   . ILE B 2 327 ? 110.848 82.832  91.391  1.00 191.47 ? 327 ILE B C   1 
ATOM   5657  O O   . ILE B 2 327 ? 110.268 83.471  90.497  1.00 214.37 ? 327 ILE B O   1 
ATOM   5658  C CB  . ILE B 2 327 ? 109.397 81.504  93.071  1.00 187.05 ? 327 ILE B CB  1 
ATOM   5659  C CG1 . ILE B 2 327 ? 108.752 80.139  93.358  1.00 201.45 ? 327 ILE B CG1 1 
ATOM   5660  C CG2 . ILE B 2 327 ? 108.331 82.585  92.943  1.00 167.45 ? 327 ILE B CG2 1 
ATOM   5661  C CD1 . ILE B 2 327 ? 107.723 79.654  92.345  1.00 198.15 ? 327 ILE B CD1 1 
ATOM   5662  N N   . PRO B 2 328 ? 111.961 83.329  91.976  1.00 170.32 ? 328 PRO B N   1 
ATOM   5663  C CA  . PRO B 2 328 ? 112.560 84.593  91.543  1.00 166.67 ? 328 PRO B CA  1 
ATOM   5664  C C   . PRO B 2 328 ? 112.915 84.640  90.063  1.00 220.31 ? 328 PRO B C   1 
ATOM   5665  O O   . PRO B 2 328 ? 112.734 85.687  89.444  1.00 289.91 ? 328 PRO B O   1 
ATOM   5666  C CB  . PRO B 2 328 ? 113.845 84.694  92.371  1.00 222.81 ? 328 PRO B CB  1 
ATOM   5667  C CG  . PRO B 2 328 ? 113.512 83.874  93.607  1.00 298.54 ? 328 PRO B CG  1 
ATOM   5668  C CD  . PRO B 2 328 ? 112.694 82.718  93.086  1.00 210.98 ? 328 PRO B CD  1 
ATOM   5669  N N   . VAL B 2 329 ? 113.403 83.512  89.512  1.00 225.81 ? 329 VAL B N   1 
ATOM   5670  C CA  . VAL B 2 329 ? 113.811 83.428  88.115  1.00 226.16 ? 329 VAL B CA  1 
ATOM   5671  C C   . VAL B 2 329 ? 112.577 83.398  87.211  1.00 201.49 ? 329 VAL B C   1 
ATOM   5672  O O   . VAL B 2 329 ? 112.473 84.255  86.335  1.00 208.25 ? 329 VAL B O   1 
ATOM   5673  C CB  . VAL B 2 329 ? 114.747 82.228  87.873  1.00 234.19 ? 329 VAL B CB  1 
ATOM   5674  C CG1 . VAL B 2 329 ? 114.957 81.930  86.395  1.00 232.12 ? 329 VAL B CG1 1 
ATOM   5675  C CG2 . VAL B 2 329 ? 116.074 82.459  88.572  1.00 332.14 ? 329 VAL B CG2 1 
ATOM   5676  N N   . PHE B 2 330 ? 111.663 82.433  87.420  1.00 169.23 ? 330 PHE B N   1 
ATOM   5677  C CA  . PHE B 2 330 ? 110.527 82.238  86.522  1.00 219.51 ? 330 PHE B CA  1 
ATOM   5678  C C   . PHE B 2 330 ? 109.568 83.438  86.584  1.00 201.56 ? 330 PHE B C   1 
ATOM   5679  O O   . PHE B 2 330 ? 109.061 83.860  85.542  1.00 178.51 ? 330 PHE B O   1 
ATOM   5680  C CB  . PHE B 2 330 ? 109.876 80.865  86.759  1.00 220.22 ? 330 PHE B CB  1 
ATOM   5681  C CG  . PHE B 2 330 ? 110.805 79.710  86.445  1.00 289.65 ? 330 PHE B CG  1 
ATOM   5682  C CD1 . PHE B 2 330 ? 111.435 79.605  85.202  1.00 326.77 ? 330 PHE B CD1 1 
ATOM   5683  C CD2 . PHE B 2 330 ? 111.071 78.726  87.391  1.00 357.37 ? 330 PHE B CD2 1 
ATOM   5684  C CE1 . PHE B 2 330 ? 112.298 78.551  84.916  1.00 358.05 ? 330 PHE B CE1 1 
ATOM   5685  C CE2 . PHE B 2 330 ? 111.935 77.670  87.107  1.00 418.24 ? 330 PHE B CE2 1 
ATOM   5686  C CZ  . PHE B 2 330 ? 112.547 77.584  85.870  1.00 409.65 ? 330 PHE B CZ  1 
ATOM   5687  N N   . VAL B 2 331 ? 109.319 84.011  87.771  1.00 183.48 ? 331 VAL B N   1 
ATOM   5688  C CA  . VAL B 2 331 ? 108.469 85.198  87.833  1.00 176.79 ? 331 VAL B CA  1 
ATOM   5689  C C   . VAL B 2 331 ? 109.206 86.410  87.256  1.00 166.15 ? 331 VAL B C   1 
ATOM   5690  O O   . VAL B 2 331 ? 108.619 87.199  86.513  1.00 180.70 ? 331 VAL B O   1 
ATOM   5691  C CB  . VAL B 2 331 ? 107.973 85.496  89.253  1.00 156.97 ? 331 VAL B CB  1 
ATOM   5692  C CG1 . VAL B 2 331 ? 107.268 86.836  89.352  1.00 132.94 ? 331 VAL B CG1 1 
ATOM   5693  C CG2 . VAL B 2 331 ? 107.069 84.390  89.734  1.00 164.48 ? 331 VAL B CG2 1 
ATOM   5694  N N   . GLY B 2 332 ? 110.483 86.576  87.598  1.00 153.40 ? 332 GLY B N   1 
ATOM   5695  C CA  . GLY B 2 332 ? 111.271 87.635  86.997  1.00 180.21 ? 332 GLY B CA  1 
ATOM   5696  C C   . GLY B 2 332 ? 111.187 87.615  85.472  1.00 203.52 ? 332 GLY B C   1 
ATOM   5697  O O   . GLY B 2 332 ? 110.884 88.644  84.867  1.00 217.20 ? 332 GLY B O   1 
ATOM   5698  N N   . LEU B 2 333 ? 111.444 86.446  84.862  1.00 204.02 ? 333 LEU B N   1 
ATOM   5699  C CA  . LEU B 2 333 ? 111.393 86.325  83.413  1.00 192.83 ? 333 LEU B CA  1 
ATOM   5700  C C   . LEU B 2 333 ? 110.000 86.661  82.889  1.00 180.32 ? 333 LEU B C   1 
ATOM   5701  O O   . LEU B 2 333 ? 109.940 87.296  81.835  1.00 221.46 ? 333 LEU B O   1 
ATOM   5702  C CB  . LEU B 2 333 ? 111.818 84.927  82.974  1.00 189.13 ? 333 LEU B CB  1 
ATOM   5703  C CG  . LEU B 2 333 ? 113.306 84.619  83.111  1.00 267.69 ? 333 LEU B CG  1 
ATOM   5704  C CD1 . LEU B 2 333 ? 113.583 83.197  82.649  1.00 340.70 ? 333 LEU B CD1 1 
ATOM   5705  C CD2 . LEU B 2 333 ? 114.158 85.605  82.322  1.00 323.61 ? 333 LEU B CD2 1 
ATOM   5706  N N   . SER B 2 334 ? 108.913 86.273  83.589  1.00 130.84 ? 334 SER B N   1 
ATOM   5707  C CA  . SER B 2 334 ? 107.576 86.647  83.128  1.00 173.25 ? 334 SER B CA  1 
ATOM   5708  C C   . SER B 2 334 ? 107.391 88.172  83.043  1.00 158.98 ? 334 SER B C   1 
ATOM   5709  O O   . SER B 2 334 ? 106.768 88.668  82.102  1.00 140.14 ? 334 SER B O   1 
ATOM   5710  C CB  . SER B 2 334 ? 106.487 86.035  83.941  1.00 176.73 ? 334 SER B CB  1 
ATOM   5711  O OG  . SER B 2 334 ? 106.258 86.765  85.118  1.00 174.46 ? 334 SER B OG  1 
ATOM   5712  N N   . CYS B 2 335 ? 107.939 88.910  84.007  1.00 164.85 ? 335 CYS B N   1 
ATOM   5713  C CA  . CYS B 2 335 ? 107.840 90.363  84.024  1.00 156.89 ? 335 CYS B CA  1 
ATOM   5714  C C   . CYS B 2 335 ? 108.778 91.001  82.998  1.00 150.63 ? 335 CYS B C   1 
ATOM   5715  O O   . CYS B 2 335 ? 108.443 92.017  82.401  1.00 188.19 ? 335 CYS B O   1 
ATOM   5716  C CB  . CYS B 2 335 ? 108.170 90.880  85.414  1.00 180.99 ? 335 CYS B CB  1 
ATOM   5717  S SG  . CYS B 2 335 ? 107.137 90.127  86.680  1.00 188.11 ? 335 CYS B SG  1 
ATOM   5718  N N   . PHE B 2 336 ? 109.958 90.421  82.779  1.00 131.45 ? 336 PHE B N   1 
ATOM   5719  C CA  . PHE B 2 336 ? 110.824 90.844  81.696  1.00 151.09 ? 336 PHE B CA  1 
ATOM   5720  C C   . PHE B 2 336 ? 110.115 90.669  80.350  1.00 164.48 ? 336 PHE B C   1 
ATOM   5721  O O   . PHE B 2 336 ? 110.239 91.507  79.466  1.00 156.96 ? 336 PHE B O   1 
ATOM   5722  C CB  . PHE B 2 336 ? 112.091 90.009  81.779  1.00 175.59 ? 336 PHE B CB  1 
ATOM   5723  C CG  . PHE B 2 336 ? 113.265 90.496  80.991  1.00 201.49 ? 336 PHE B CG  1 
ATOM   5724  C CD1 . PHE B 2 336 ? 114.062 91.518  81.483  1.00 184.52 ? 336 PHE B CD1 1 
ATOM   5725  C CD2 . PHE B 2 336 ? 113.572 89.915  79.771  1.00 219.54 ? 336 PHE B CD2 1 
ATOM   5726  C CE1 . PHE B 2 336 ? 115.160 91.957  80.762  1.00 251.45 ? 336 PHE B CE1 1 
ATOM   5727  C CE2 . PHE B 2 336 ? 114.676 90.353  79.051  1.00 262.97 ? 336 PHE B CE2 1 
ATOM   5728  C CZ  . PHE B 2 336 ? 115.464 91.373  79.545  1.00 271.88 ? 336 PHE B CZ  1 
ATOM   5729  N N   . GLY B 2 337 ? 109.360 89.575  80.191  1.00 168.72 ? 337 GLY B N   1 
ATOM   5730  C CA  . GLY B 2 337 ? 108.484 89.383  79.049  1.00 164.54 ? 337 GLY B CA  1 
ATOM   5731  C C   . GLY B 2 337 ? 107.361 90.413  78.951  1.00 150.91 ? 337 GLY B C   1 
ATOM   5732  O O   . GLY B 2 337 ? 107.065 90.853  77.843  1.00 209.46 ? 337 GLY B O   1 
ATOM   5733  N N   . SER B 2 338 ? 106.730 90.782  80.073  1.00 126.41 ? 338 SER B N   1 
ATOM   5734  C CA  . SER B 2 338 ? 105.596 91.707  80.059  1.00 165.80 ? 338 SER B CA  1 
ATOM   5735  C C   . SER B 2 338 ? 106.013 93.167  79.812  1.00 174.18 ? 338 SER B C   1 
ATOM   5736  O O   . SER B 2 338 ? 105.236 93.918  79.226  1.00 181.72 ? 338 SER B O   1 
ATOM   5737  C CB  . SER B 2 338 ? 104.784 91.580  81.325  1.00 189.71 ? 338 SER B CB  1 
ATOM   5738  O OG  . SER B 2 338 ? 104.140 90.317  81.388  1.00 240.37 ? 338 SER B OG  1 
ATOM   5739  N N   . VAL B 2 339 ? 107.212 93.587  80.255  1.00 157.70 ? 339 VAL B N   1 
ATOM   5740  C CA  . VAL B 2 339 ? 107.722 94.913  79.937  1.00 137.98 ? 339 VAL B CA  1 
ATOM   5741  C C   . VAL B 2 339 ? 108.059 94.935  78.454  1.00 176.29 ? 339 VAL B C   1 
ATOM   5742  O O   . VAL B 2 339 ? 107.699 95.888  77.776  1.00 197.64 ? 339 VAL B O   1 
ATOM   5743  C CB  . VAL B 2 339 ? 108.943 95.296  80.788  1.00 195.98 ? 339 VAL B CB  1 
ATOM   5744  C CG1 . VAL B 2 339 ? 109.708 96.521  80.280  1.00 211.73 ? 339 VAL B CG1 1 
ATOM   5745  C CG2 . VAL B 2 339 ? 108.514 95.511  82.221  1.00 256.52 ? 339 VAL B CG2 1 
ATOM   5746  N N   . ASN B 2 340 ? 108.734 93.888  77.960  1.00 174.58 ? 340 ASN B N   1 
ATOM   5747  C CA  . ASN B 2 340 ? 109.080 93.774  76.547  1.00 167.77 ? 340 ASN B CA  1 
ATOM   5748  C C   . ASN B 2 340 ? 107.838 93.885  75.654  1.00 136.27 ? 340 ASN B C   1 
ATOM   5749  O O   . ASN B 2 340 ? 107.840 94.648  74.687  1.00 116.90 ? 340 ASN B O   1 
ATOM   5750  C CB  . ASN B 2 340 ? 109.856 92.475  76.317  1.00 174.77 ? 340 ASN B CB  1 
ATOM   5751  C CG  . ASN B 2 340 ? 110.201 92.265  74.869  1.00 165.13 ? 340 ASN B CG  1 
ATOM   5752  O OD1 . ASN B 2 340 ? 110.745 93.183  74.256  1.00 186.77 ? 340 ASN B OD1 1 
ATOM   5753  N ND2 . ASN B 2 340 ? 109.890 91.092  74.325  1.00 171.73 ? 340 ASN B ND2 1 
ATOM   5754  N N   . GLY B 2 341 ? 106.778 93.131  75.995  1.00 157.96 ? 341 GLY B N   1 
ATOM   5755  C CA  . GLY B 2 341 ? 105.515 93.137  75.263  1.00 192.64 ? 341 GLY B CA  1 
ATOM   5756  C C   . GLY B 2 341 ? 104.839 94.508  75.162  1.00 158.52 ? 341 GLY B C   1 
ATOM   5757  O O   . GLY B 2 341 ? 104.318 94.868  74.109  1.00 178.61 ? 341 GLY B O   1 
ATOM   5758  N N   . SER B 2 342 ? 104.863 95.265  76.255  1.00 136.09 ? 342 SER B N   1 
ATOM   5759  C CA  . SER B 2 342 ? 104.260 96.585  76.289  1.00 188.40 ? 342 SER B CA  1 
ATOM   5760  C C   . SER B 2 342 ? 105.050 97.591  75.456  1.00 170.58 ? 342 SER B C   1 
ATOM   5761  O O   . SER B 2 342 ? 104.447 98.571  75.025  1.00 202.83 ? 342 SER B O   1 
ATOM   5762  C CB  . SER B 2 342 ? 104.103 97.080  77.704  1.00 291.95 ? 342 SER B CB  1 
ATOM   5763  O OG  . SER B 2 342 ? 103.318 98.261  77.721  1.00 302.97 ? 342 SER B OG  1 
ATOM   5764  N N   . LEU B 2 343 ? 106.368 97.375  75.259  1.00 147.64 ? 343 LEU B N   1 
ATOM   5765  C CA  . LEU B 2 343 ? 107.162 98.235  74.390  1.00 158.03 ? 343 LEU B CA  1 
ATOM   5766  C C   . LEU B 2 343 ? 106.891 97.876  72.936  1.00 166.15 ? 343 LEU B C   1 
ATOM   5767  O O   . LEU B 2 343 ? 106.561 98.768  72.151  1.00 161.73 ? 343 LEU B O   1 
ATOM   5768  C CB  . LEU B 2 343 ? 108.653 98.125  74.734  1.00 154.32 ? 343 LEU B CB  1 
ATOM   5769  C CG  . LEU B 2 343 ? 109.045 98.791  76.045  1.00 188.49 ? 343 LEU B CG  1 
ATOM   5770  C CD1 . LEU B 2 343 ? 110.380 98.232  76.520  1.00 221.02 ? 343 LEU B CD1 1 
ATOM   5771  C CD2 . LEU B 2 343 ? 109.065 100.339 75.944  1.00 141.20 ? 343 LEU B CD2 1 
ATOM   5772  N N   . PHE B 2 344 ? 107.025 96.584  72.605  1.00 194.40 ? 344 PHE B N   1 
ATOM   5773  C CA  . PHE B 2 344 ? 106.886 96.058  71.249  1.00 209.47 ? 344 PHE B CA  1 
ATOM   5774  C C   . PHE B 2 344 ? 105.548 96.447  70.610  1.00 168.01 ? 344 PHE B C   1 
ATOM   5775  O O   . PHE B 2 344 ? 105.510 96.838  69.435  1.00 149.70 ? 344 PHE B O   1 
ATOM   5776  C CB  . PHE B 2 344 ? 107.085 94.541  71.307  1.00 217.76 ? 344 PHE B CB  1 
ATOM   5777  C CG  . PHE B 2 344 ? 106.815 93.778  70.036  1.00 194.32 ? 344 PHE B CG  1 
ATOM   5778  C CD1 . PHE B 2 344 ? 107.338 94.200  68.823  1.00 240.25 ? 344 PHE B CD1 1 
ATOM   5779  C CD2 . PHE B 2 344 ? 106.040 92.629  70.059  1.00 256.05 ? 344 PHE B CD2 1 
ATOM   5780  C CE1 . PHE B 2 344 ? 107.096 93.489  67.656  1.00 319.66 ? 344 PHE B CE1 1 
ATOM   5781  C CE2 . PHE B 2 344 ? 105.788 91.923  68.895  1.00 330.37 ? 344 PHE B CE2 1 
ATOM   5782  C CZ  . PHE B 2 344 ? 106.315 92.353  67.695  1.00 353.73 ? 344 PHE B CZ  1 
ATOM   5783  N N   . THR B 2 345 ? 104.464 96.340  71.391  1.00 158.25 ? 345 THR B N   1 
ATOM   5784  C CA  . THR B 2 345 ? 103.126 96.609  70.883  1.00 193.75 ? 345 THR B CA  1 
ATOM   5785  C C   . THR B 2 345 ? 102.715 98.086  70.969  1.00 164.28 ? 345 THR B C   1 
ATOM   5786  O O   . THR B 2 345 ? 101.574 98.388  70.607  1.00 292.38 ? 345 THR B O   1 
ATOM   5787  C CB  . THR B 2 345 ? 102.081 95.702  71.560  1.00 260.94 ? 345 THR B CB  1 
ATOM   5788  O OG1 . THR B 2 345 ? 101.990 95.974  72.956  1.00 276.61 ? 345 THR B OG1 1 
ATOM   5789  C CG2 . THR B 2 345 ? 102.379 94.228  71.360  1.00 312.30 ? 345 THR B CG2 1 
ATOM   5790  N N   . SER B 2 346 ? 103.598 99.010  71.398  1.00 166.72 ? 346 SER B N   1 
ATOM   5791  C CA  . SER B 2 346 ? 103.245 100.422 71.610  1.00 202.59 ? 346 SER B CA  1 
ATOM   5792  C C   . SER B 2 346 ? 103.136 101.219 70.306  1.00 226.60 ? 346 SER B C   1 
ATOM   5793  O O   . SER B 2 346 ? 102.277 102.093 70.199  1.00 254.64 ? 346 SER B O   1 
ATOM   5794  C CB  . SER B 2 346 ? 104.221 101.116 72.519  1.00 202.00 ? 346 SER B CB  1 
ATOM   5795  O OG  . SER B 2 346 ? 105.503 101.214 71.909  1.00 206.81 ? 346 SER B OG  1 
ATOM   5796  N N   . SER B 2 347 ? 104.008 100.918 69.330  1.00 216.50 ? 347 SER B N   1 
ATOM   5797  C CA  . SER B 2 347 ? 104.177 101.649 68.080  1.00 202.78 ? 347 SER B CA  1 
ATOM   5798  C C   . SER B 2 347 ? 102.859 101.918 67.345  1.00 200.35 ? 347 SER B C   1 
ATOM   5799  O O   . SER B 2 347 ? 102.686 102.974 66.724  1.00 194.36 ? 347 SER B O   1 
ATOM   5800  C CB  . SER B 2 347 ? 105.091 100.858 67.168  1.00 246.88 ? 347 SER B CB  1 
ATOM   5801  O OG  . SER B 2 347 ? 106.106 100.186 67.892  1.00 261.61 ? 347 SER B OG  1 
ATOM   5802  N N   . ARG B 2 348 ? 101.951 100.929 67.392  1.00 191.99 ? 348 ARG B N   1 
ATOM   5803  C CA  . ARG B 2 348 ? 100.662 100.949 66.716  1.00 207.22 ? 348 ARG B CA  1 
ATOM   5804  C C   . ARG B 2 348 ? 99.902  102.247 67.025  1.00 189.26 ? 348 ARG B C   1 
ATOM   5805  O O   . ARG B 2 348 ? 99.314  102.839 66.118  1.00 244.04 ? 348 ARG B O   1 
ATOM   5806  C CB  . ARG B 2 348 ? 99.805  99.745  67.135  1.00 265.20 ? 348 ARG B CB  1 
ATOM   5807  C CG  . ARG B 2 348 ? 100.398 98.353  66.922  1.00 253.18 ? 348 ARG B CG  1 
ATOM   5808  C CD  . ARG B 2 348 ? 99.508  97.267  67.526  1.00 337.56 ? 348 ARG B CD  1 
ATOM   5809  N NE  . ARG B 2 348 ? 99.276  97.411  68.971  1.00 438.62 ? 348 ARG B NE  1 
ATOM   5810  C CZ  . ARG B 2 348 ? 98.132  97.159  69.625  1.00 475.53 ? 348 ARG B CZ  1 
ATOM   5811  N NH1 . ARG B 2 348 ? 98.009  97.510  70.895  1.00 484.12 ? 348 ARG B NH1 1 
ATOM   5812  N NH2 . ARG B 2 348 ? 97.103  96.566  69.035  1.00 475.43 ? 348 ARG B NH2 1 
ATOM   5813  N N   . LEU B 2 349 ? 99.914  102.691 68.292  1.00 149.48 ? 349 LEU B N   1 
ATOM   5814  C CA  . LEU B 2 349 ? 99.176  103.877 68.714  1.00 163.32 ? 349 LEU B CA  1 
ATOM   5815  C C   . LEU B 2 349 ? 99.828  105.158 68.192  1.00 168.04 ? 349 LEU B C   1 
ATOM   5816  O O   . LEU B 2 349 ? 99.134  106.104 67.850  1.00 203.38 ? 349 LEU B O   1 
ATOM   5817  C CB  . LEU B 2 349 ? 99.105  103.903 70.242  1.00 209.81 ? 349 LEU B CB  1 
ATOM   5818  C CG  . LEU B 2 349 ? 98.343  105.058 70.895  1.00 209.49 ? 349 LEU B CG  1 
ATOM   5819  C CD1 . LEU B 2 349 ? 96.908  105.119 70.403  1.00 198.33 ? 349 LEU B CD1 1 
ATOM   5820  C CD2 . LEU B 2 349 ? 98.368  104.875 72.403  1.00 267.61 ? 349 LEU B CD2 1 
ATOM   5821  N N   . PHE B 2 350 ? 101.153 105.210 68.116  1.00 158.18 ? 350 PHE B N   1 
ATOM   5822  C CA  . PHE B 2 350 ? 101.830 106.367 67.564  1.00 206.45 ? 350 PHE B CA  1 
ATOM   5823  C C   . PHE B 2 350 ? 101.584 106.495 66.059  1.00 238.73 ? 350 PHE B C   1 
ATOM   5824  O O   . PHE B 2 350 ? 101.306 107.594 65.580  1.00 252.09 ? 350 PHE B O   1 
ATOM   5825  C CB  . PHE B 2 350 ? 103.325 106.263 67.858  1.00 235.83 ? 350 PHE B CB  1 
ATOM   5826  C CG  . PHE B 2 350 ? 103.641 106.349 69.321  1.00 209.89 ? 350 PHE B CG  1 
ATOM   5827  C CD1 . PHE B 2 350 ? 103.805 107.582 69.937  1.00 201.86 ? 350 PHE B CD1 1 
ATOM   5828  C CD2 . PHE B 2 350 ? 103.760 105.200 70.077  1.00 230.82 ? 350 PHE B CD2 1 
ATOM   5829  C CE1 . PHE B 2 350 ? 104.095 107.660 71.288  1.00 237.69 ? 350 PHE B CE1 1 
ATOM   5830  C CE2 . PHE B 2 350 ? 104.043 105.275 71.432  1.00 354.05 ? 350 PHE B CE2 1 
ATOM   5831  C CZ  . PHE B 2 350 ? 104.214 106.504 72.033  1.00 352.26 ? 350 PHE B CZ  1 
ATOM   5832  N N   . PHE B 2 351 ? 101.697 105.389 65.307  1.00 216.42 ? 351 PHE B N   1 
ATOM   5833  C CA  . PHE B 2 351 ? 101.433 105.410 63.875  1.00 225.25 ? 351 PHE B CA  1 
ATOM   5834  C C   . PHE B 2 351 ? 100.020 105.932 63.618  1.00 208.61 ? 351 PHE B C   1 
ATOM   5835  O O   . PHE B 2 351 ? 99.861  106.898 62.868  1.00 223.04 ? 351 PHE B O   1 
ATOM   5836  C CB  . PHE B 2 351 ? 101.617 104.026 63.245  1.00 252.20 ? 351 PHE B CB  1 
ATOM   5837  C CG  . PHE B 2 351 ? 103.021 103.462 63.184  1.00 285.08 ? 351 PHE B CG  1 
ATOM   5838  C CD1 . PHE B 2 351 ? 104.140 104.175 63.606  1.00 246.12 ? 351 PHE B CD1 1 
ATOM   5839  C CD2 . PHE B 2 351 ? 103.219 102.175 62.687  1.00 309.95 ? 351 PHE B CD2 1 
ATOM   5840  C CE1 . PHE B 2 351 ? 105.411 103.614 63.534  1.00 282.80 ? 351 PHE B CE1 1 
ATOM   5841  C CE2 . PHE B 2 351 ? 104.491 101.618 62.609  1.00 303.27 ? 351 PHE B CE2 1 
ATOM   5842  C CZ  . PHE B 2 351 ? 105.586 102.340 63.041  1.00 330.80 ? 351 PHE B CZ  1 
ATOM   5843  N N   . VAL B 2 352 ? 99.021  105.306 64.255  1.00 199.77 ? 352 VAL B N   1 
ATOM   5844  C CA  . VAL B 2 352 ? 97.622  105.688 64.095  1.00 233.85 ? 352 VAL B CA  1 
ATOM   5845  C C   . VAL B 2 352 ? 97.403  107.147 64.535  1.00 190.67 ? 352 VAL B C   1 
ATOM   5846  O O   . VAL B 2 352 ? 96.812  107.922 63.785  1.00 247.56 ? 352 VAL B O   1 
ATOM   5847  C CB  . VAL B 2 352 ? 96.693  104.667 64.797  1.00 275.48 ? 352 VAL B CB  1 
ATOM   5848  C CG1 . VAL B 2 352 ? 95.256  105.155 64.976  1.00 241.47 ? 352 VAL B CG1 1 
ATOM   5849  C CG2 . VAL B 2 352 ? 96.704  103.329 64.055  1.00 271.24 ? 352 VAL B CG2 1 
ATOM   5850  N N   . GLY B 2 353 ? 97.884  107.539 65.717  1.00 204.70 ? 353 GLY B N   1 
ATOM   5851  C CA  . GLY B 2 353 ? 97.689  108.884 66.242  1.00 237.88 ? 353 GLY B CA  1 
ATOM   5852  C C   . GLY B 2 353 ? 98.325  110.000 65.413  1.00 213.31 ? 353 GLY B C   1 
ATOM   5853  O O   . GLY B 2 353 ? 97.821  111.113 65.431  1.00 190.16 ? 353 GLY B O   1 
ATOM   5854  N N   . SER B 2 354 ? 99.412  109.704 64.688  1.00 232.24 ? 354 SER B N   1 
ATOM   5855  C CA  . SER B 2 354 ? 100.036 110.663 63.778  1.00 286.68 ? 354 SER B CA  1 
ATOM   5856  C C   . SER B 2 354 ? 99.400  110.628 62.378  1.00 321.51 ? 354 SER B C   1 
ATOM   5857  O O   . SER B 2 354 ? 99.261  111.686 61.753  1.00 250.96 ? 354 SER B O   1 
ATOM   5858  C CB  . SER B 2 354 ? 101.537 110.466 63.761  1.00 262.35 ? 354 SER B CB  1 
ATOM   5859  O OG  . SER B 2 354 ? 101.859 109.133 63.408  1.00 296.75 ? 354 SER B OG  1 
ATOM   5860  N N   . ARG B 2 355 ? 99.003  109.438 61.888  1.00 319.28 ? 355 ARG B N   1 
ATOM   5861  C CA  . ARG B 2 355 ? 98.273  109.298 60.629  1.00 252.74 ? 355 ARG B CA  1 
ATOM   5862  C C   . ARG B 2 355 ? 96.955  110.083 60.663  1.00 240.86 ? 355 ARG B C   1 
ATOM   5863  O O   . ARG B 2 355 ? 96.645  110.790 59.702  1.00 264.66 ? 355 ARG B O   1 
ATOM   5864  C CB  . ARG B 2 355 ? 98.015  107.818 60.331  1.00 249.24 ? 355 ARG B CB  1 
ATOM   5865  C CG  . ARG B 2 355 ? 97.474  107.544 58.932  1.00 246.77 ? 355 ARG B CG  1 
ATOM   5866  C CD  . ARG B 2 355 ? 97.043  106.098 58.753  1.00 323.80 ? 355 ARG B CD  1 
ATOM   5867  N NE  . ARG B 2 355 ? 95.775  105.822 59.423  1.00 349.94 ? 355 ARG B NE  1 
ATOM   5868  C CZ  . ARG B 2 355 ? 95.215  104.620 59.589  1.00 364.68 ? 355 ARG B CZ  1 
ATOM   5869  N NH1 . ARG B 2 355 ? 94.022  104.539 60.156  1.00 356.11 ? 355 ARG B NH1 1 
ATOM   5870  N NH2 . ARG B 2 355 ? 95.828  103.513 59.198  1.00 353.51 ? 355 ARG B NH2 1 
ATOM   5871  N N   . GLU B 2 356 ? 96.194  109.967 61.770  1.00 251.24 ? 356 GLU B N   1 
ATOM   5872  C CA  . GLU B 2 356 ? 94.948  110.711 61.974  1.00 276.23 ? 356 GLU B CA  1 
ATOM   5873  C C   . GLU B 2 356 ? 95.174  112.130 62.525  1.00 255.04 ? 356 GLU B C   1 
ATOM   5874  O O   . GLU B 2 356 ? 94.200  112.816 62.855  1.00 210.12 ? 356 GLU B O   1 
ATOM   5875  C CB  . GLU B 2 356 ? 94.002  109.931 62.899  1.00 297.55 ? 356 GLU B CB  1 
ATOM   5876  C CG  . GLU B 2 356 ? 93.703  108.495 62.459  1.00 338.16 ? 356 GLU B CG  1 
ATOM   5877  C CD  . GLU B 2 356 ? 93.250  108.298 61.016  1.00 322.87 ? 356 GLU B CD  1 
ATOM   5878  O OE1 . GLU B 2 356 ? 92.544  109.186 60.502  1.00 360.53 ? 356 GLU B OE1 1 
ATOM   5879  O OE2 . GLU B 2 356 ? 93.589  107.261 60.407  1.00 235.39 ? 356 GLU B OE2 1 
ATOM   5880  N N   . GLY B 2 357 ? 96.439  112.578 62.635  1.00 228.66 ? 357 GLY B N   1 
ATOM   5881  C CA  . GLY B 2 357 ? 96.782  113.995 62.641  1.00 243.47 ? 357 GLY B CA  1 
ATOM   5882  C C   . GLY B 2 357 ? 96.790  114.645 64.022  1.00 262.51 ? 357 GLY B C   1 
ATOM   5883  O O   . GLY B 2 357 ? 97.024  115.851 64.098  1.00 281.54 ? 357 GLY B O   1 
ATOM   5884  N N   . HIS B 2 358 ? 96.555  113.866 65.095  1.00 277.44 ? 358 HIS B N   1 
ATOM   5885  C CA  . HIS B 2 358 ? 96.600  114.364 66.470  1.00 296.39 ? 358 HIS B CA  1 
ATOM   5886  C C   . HIS B 2 358 ? 98.038  114.476 66.997  1.00 246.25 ? 358 HIS B C   1 
ATOM   5887  O O   . HIS B 2 358 ? 98.309  115.330 67.849  1.00 176.65 ? 358 HIS B O   1 
ATOM   5888  C CB  . HIS B 2 358 ? 95.750  113.484 67.409  1.00 269.73 ? 358 HIS B CB  1 
ATOM   5889  C CG  . HIS B 2 358 ? 94.292  113.801 67.383  1.00 256.98 ? 358 HIS B CG  1 
ATOM   5890  N ND1 . HIS B 2 358 ? 93.299  112.968 66.917  1.00 303.44 ? 358 HIS B ND1 1 
ATOM   5891  C CD2 . HIS B 2 358 ? 93.672  114.921 67.765  1.00 278.27 ? 358 HIS B CD2 1 
ATOM   5892  C CE1 . HIS B 2 358 ? 92.130  113.571 67.026  1.00 349.12 ? 358 HIS B CE1 1 
ATOM   5893  N NE2 . HIS B 2 358 ? 92.333  114.759 67.544  1.00 328.87 ? 358 HIS B NE2 1 
ATOM   5894  N N   . LEU B 2 359 ? 98.958  113.624 66.511  1.00 216.77 ? 359 LEU B N   1 
ATOM   5895  C CA  . LEU B 2 359 ? 100.249 113.451 67.165  1.00 216.01 ? 359 LEU B CA  1 
ATOM   5896  C C   . LEU B 2 359 ? 101.408 113.905 66.262  1.00 238.67 ? 359 LEU B C   1 
ATOM   5897  O O   . LEU B 2 359 ? 101.414 113.585 65.077  1.00 233.36 ? 359 LEU B O   1 
ATOM   5898  C CB  . LEU B 2 359 ? 100.363 111.978 67.572  1.00 243.85 ? 359 LEU B CB  1 
ATOM   5899  C CG  . LEU B 2 359 ? 101.403 111.647 68.641  1.00 325.22 ? 359 LEU B CG  1 
ATOM   5900  C CD1 . LEU B 2 359 ? 101.034 112.239 70.002  1.00 387.92 ? 359 LEU B CD1 1 
ATOM   5901  C CD2 . LEU B 2 359 ? 101.538 110.126 68.762  1.00 243.93 ? 359 LEU B CD2 1 
ATOM   5902  N N   . PRO B 2 360 ? 102.416 114.660 66.799  1.00 270.68 ? 360 PRO B N   1 
ATOM   5903  C CA  . PRO B 2 360 ? 103.568 115.181 66.030  1.00 255.37 ? 360 PRO B CA  1 
ATOM   5904  C C   . PRO B 2 360 ? 104.290 114.215 65.082  1.00 226.10 ? 360 PRO B C   1 
ATOM   5905  O O   . PRO B 2 360 ? 104.510 113.041 65.394  1.00 188.97 ? 360 PRO B O   1 
ATOM   5906  C CB  . PRO B 2 360 ? 104.563 115.602 67.126  1.00 236.07 ? 360 PRO B CB  1 
ATOM   5907  C CG  . PRO B 2 360 ? 103.650 116.062 68.247  1.00 245.82 ? 360 PRO B CG  1 
ATOM   5908  C CD  . PRO B 2 360 ? 102.496 115.078 68.213  1.00 255.89 ? 360 PRO B CD  1 
ATOM   5909  N N   . SER B 2 361 ? 104.649 114.754 63.910  1.00 234.54 ? 361 SER B N   1 
ATOM   5910  C CA  . SER B 2 361 ? 105.016 113.973 62.735  1.00 291.53 ? 361 SER B CA  1 
ATOM   5911  C C   . SER B 2 361 ? 106.281 113.134 62.967  1.00 235.36 ? 361 SER B C   1 
ATOM   5912  O O   . SER B 2 361 ? 106.412 112.044 62.415  1.00 166.85 ? 361 SER B O   1 
ATOM   5913  C CB  . SER B 2 361 ? 105.160 114.880 61.533  1.00 333.49 ? 361 SER B CB  1 
ATOM   5914  O OG  . SER B 2 361 ? 106.067 115.940 61.801  1.00 373.32 ? 361 SER B OG  1 
ATOM   5915  N N   . ILE B 2 362 ? 107.207 113.638 63.790  1.00 188.36 ? 362 ILE B N   1 
ATOM   5916  C CA  . ILE B 2 362 ? 108.430 112.911 64.137  1.00 201.41 ? 362 ILE B CA  1 
ATOM   5917  C C   . ILE B 2 362 ? 108.126 111.578 64.842  1.00 219.26 ? 362 ILE B C   1 
ATOM   5918  O O   . ILE B 2 362 ? 108.854 110.605 64.642  1.00 163.90 ? 362 ILE B O   1 
ATOM   5919  C CB  . ILE B 2 362 ? 109.401 113.825 64.936  1.00 225.70 ? 362 ILE B CB  1 
ATOM   5920  C CG1 . ILE B 2 362 ? 110.684 113.117 65.406  1.00 233.22 ? 362 ILE B CG1 1 
ATOM   5921  C CG2 . ILE B 2 362 ? 108.701 114.511 66.110  1.00 221.14 ? 362 ILE B CG2 1 
ATOM   5922  C CD1 . ILE B 2 362 ? 111.547 112.472 64.329  1.00 185.55 ? 362 ILE B CD1 1 
ATOM   5923  N N   . LEU B 2 363 ? 107.075 111.495 65.669  1.00 237.77 ? 363 LEU B N   1 
ATOM   5924  C CA  . LEU B 2 363 ? 106.821 110.262 66.413  1.00 215.98 ? 363 LEU B CA  1 
ATOM   5925  C C   . LEU B 2 363 ? 106.272 109.149 65.515  1.00 202.91 ? 363 LEU B C   1 
ATOM   5926  O O   . LEU B 2 363 ? 106.155 108.029 65.994  1.00 247.63 ? 363 LEU B O   1 
ATOM   5927  C CB  . LEU B 2 363 ? 105.880 110.573 67.584  1.00 209.64 ? 363 LEU B CB  1 
ATOM   5928  C CG  . LEU B 2 363 ? 106.438 111.548 68.626  1.00 239.26 ? 363 LEU B CG  1 
ATOM   5929  C CD1 . LEU B 2 363 ? 105.403 111.864 69.713  1.00 255.05 ? 363 LEU B CD1 1 
ATOM   5930  C CD2 . LEU B 2 363 ? 107.726 111.009 69.234  1.00 224.04 ? 363 LEU B CD2 1 
ATOM   5931  N N   . SER B 2 364 ? 105.951 109.431 64.242  1.00 172.37 ? 364 SER B N   1 
ATOM   5932  C CA  . SER B 2 364 ? 105.623 108.397 63.271  1.00 212.66 ? 364 SER B CA  1 
ATOM   5933  C C   . SER B 2 364 ? 106.849 107.641 62.761  1.00 203.33 ? 364 SER B C   1 
ATOM   5934  O O   . SER B 2 364 ? 106.703 106.544 62.225  1.00 176.66 ? 364 SER B O   1 
ATOM   5935  C CB  . SER B 2 364 ? 104.891 109.002 62.096  1.00 299.63 ? 364 SER B CB  1 
ATOM   5936  O OG  . SER B 2 364 ? 105.759 109.765 61.265  1.00 293.03 ? 364 SER B OG  1 
ATOM   5937  N N   . MET B 2 365 ? 108.047 108.225 62.887  1.00 172.34 ? 365 MET B N   1 
ATOM   5938  C CA  . MET B 2 365 ? 109.142 107.878 61.987  1.00 193.32 ? 365 MET B CA  1 
ATOM   5939  C C   . MET B 2 365 ? 109.860 106.601 62.415  1.00 165.68 ? 365 MET B C   1 
ATOM   5940  O O   . MET B 2 365 ? 109.686 106.102 63.518  1.00 205.13 ? 365 MET B O   1 
ATOM   5941  C CB  . MET B 2 365 ? 110.116 109.055 61.882  1.00 198.01 ? 365 MET B CB  1 
ATOM   5942  C CG  . MET B 2 365 ? 109.411 110.242 61.222  1.00 249.03 ? 365 MET B CG  1 
ATOM   5943  S SD  . MET B 2 365 ? 110.500 111.552 60.690  1.00 302.65 ? 365 MET B SD  1 
ATOM   5944  C CE  . MET B 2 365 ? 109.279 112.747 60.152  1.00 294.01 ? 365 MET B CE  1 
ATOM   5945  N N   . ILE B 2 366 ? 110.664 106.080 61.488  1.00 139.01 ? 366 ILE B N   1 
ATOM   5946  C CA  . ILE B 2 366 ? 111.323 104.791 61.618  1.00 170.62 ? 366 ILE B CA  1 
ATOM   5947  C C   . ILE B 2 366 ? 112.791 104.934 61.200  1.00 173.56 ? 366 ILE B C   1 
ATOM   5948  O O   . ILE B 2 366 ? 113.106 105.746 60.349  1.00 166.31 ? 366 ILE B O   1 
ATOM   5949  C CB  . ILE B 2 366 ? 110.549 103.753 60.767  1.00 180.89 ? 366 ILE B CB  1 
ATOM   5950  C CG1 . ILE B 2 366 ? 109.106 103.550 61.269  1.00 163.24 ? 366 ILE B CG1 1 
ATOM   5951  C CG2 . ILE B 2 366 ? 111.335 102.437 60.624  1.00 128.07 ? 366 ILE B CG2 1 
ATOM   5952  C CD1 . ILE B 2 366 ? 108.175 102.887 60.275  1.00 228.49 ? 366 ILE B CD1 1 
ATOM   5953  N N   . HIS B 2 367 ? 113.692 104.141 61.795  1.00 228.35 ? 367 HIS B N   1 
ATOM   5954  C CA  . HIS B 2 367 ? 115.097 104.092 61.411  1.00 219.17 ? 367 HIS B CA  1 
ATOM   5955  C C   . HIS B 2 367 ? 115.259 103.126 60.240  1.00 234.41 ? 367 HIS B C   1 
ATOM   5956  O O   . HIS B 2 367 ? 115.132 101.912 60.433  1.00 178.23 ? 367 HIS B O   1 
ATOM   5957  C CB  . HIS B 2 367 ? 115.923 103.661 62.620  1.00 296.38 ? 367 HIS B CB  1 
ATOM   5958  C CG  . HIS B 2 367 ? 117.393 103.590 62.374  1.00 272.61 ? 367 HIS B CG  1 
ATOM   5959  N ND1 . HIS B 2 367 ? 118.242 104.678 62.394  1.00 290.72 ? 367 HIS B ND1 1 
ATOM   5960  C CD2 . HIS B 2 367 ? 118.149 102.515 62.122  1.00 243.69 ? 367 HIS B CD2 1 
ATOM   5961  C CE1 . HIS B 2 367 ? 119.477 104.254 62.159  1.00 315.26 ? 367 HIS B CE1 1 
ATOM   5962  N NE2 . HIS B 2 367 ? 119.444 102.943 61.984  1.00 290.86 ? 367 HIS B NE2 1 
ATOM   5963  N N   . PRO B 2 368 ? 115.519 103.621 59.003  1.00 272.55 ? 368 PRO B N   1 
ATOM   5964  C CA  . PRO B 2 368 ? 115.315 102.815 57.794  1.00 304.25 ? 368 PRO B CA  1 
ATOM   5965  C C   . PRO B 2 368 ? 116.224 101.595 57.570  1.00 311.48 ? 368 PRO B C   1 
ATOM   5966  O O   . PRO B 2 368 ? 115.846 100.717 56.802  1.00 341.00 ? 368 PRO B O   1 
ATOM   5967  C CB  . PRO B 2 368 ? 115.515 103.821 56.646  1.00 296.79 ? 368 PRO B CB  1 
ATOM   5968  C CG  . PRO B 2 368 ? 116.336 104.947 57.239  1.00 280.80 ? 368 PRO B CG  1 
ATOM   5969  C CD  . PRO B 2 368 ? 115.990 104.984 58.706  1.00 247.40 ? 368 PRO B CD  1 
ATOM   5970  N N   . GLN B 2 369 ? 117.396 101.517 58.221  1.00 281.17 ? 369 GLN B N   1 
ATOM   5971  C CA  . GLN B 2 369 ? 118.251 100.334 58.134  1.00 280.14 ? 369 GLN B CA  1 
ATOM   5972  C C   . GLN B 2 369 ? 117.727 99.165  58.988  1.00 328.68 ? 369 GLN B C   1 
ATOM   5973  O O   . GLN B 2 369 ? 118.064 98.014  58.689  1.00 334.84 ? 369 GLN B O   1 
ATOM   5974  C CB  . GLN B 2 369 ? 119.686 100.683 58.541  1.00 295.49 ? 369 GLN B CB  1 
ATOM   5975  C CG  . GLN B 2 369 ? 120.454 101.473 57.484  1.00 318.29 ? 369 GLN B CG  1 
ATOM   5976  C CD  . GLN B 2 369 ? 120.118 102.946 57.389  1.00 397.79 ? 369 GLN B CD  1 
ATOM   5977  O OE1 . GLN B 2 369 ? 119.459 103.530 58.251  1.00 472.08 ? 369 GLN B OE1 1 
ATOM   5978  N NE2 . GLN B 2 369 ? 120.585 103.574 56.320  1.00 435.67 ? 369 GLN B NE2 1 
ATOM   5979  N N   . LEU B 2 370 ? 116.926 99.440  60.041  1.00 297.36 ? 370 LEU B N   1 
ATOM   5980  C CA  . LEU B 2 370 ? 116.470 98.425  60.996  1.00 280.65 ? 370 LEU B CA  1 
ATOM   5981  C C   . LEU B 2 370 ? 114.944 98.261  61.047  1.00 284.34 ? 370 LEU B C   1 
ATOM   5982  O O   . LEU B 2 370 ? 114.479 97.254  61.592  1.00 262.64 ? 370 LEU B O   1 
ATOM   5983  C CB  . LEU B 2 370 ? 117.005 98.805  62.383  1.00 309.53 ? 370 LEU B CB  1 
ATOM   5984  C CG  . LEU B 2 370 ? 118.527 98.884  62.524  1.00 349.10 ? 370 LEU B CG  1 
ATOM   5985  C CD1 . LEU B 2 370 ? 118.904 99.442  63.889  1.00 360.38 ? 370 LEU B CD1 1 
ATOM   5986  C CD2 . LEU B 2 370 ? 119.178 97.521  62.311  1.00 358.81 ? 370 LEU B CD2 1 
ATOM   5987  N N   . LEU B 2 371 ? 114.192 99.239  60.494  1.00 277.67 ? 371 LEU B N   1 
ATOM   5988  C CA  . LEU B 2 371 ? 112.732 99.284  60.409  1.00 285.20 ? 371 LEU B CA  1 
ATOM   5989  C C   . LEU B 2 371 ? 112.077 99.312  61.806  1.00 260.29 ? 371 LEU B C   1 
ATOM   5990  O O   . LEU B 2 371 ? 110.934 98.867  61.974  1.00 215.64 ? 371 LEU B O   1 
ATOM   5991  C CB  . LEU B 2 371 ? 112.208 98.133  59.522  1.00 378.32 ? 371 LEU B CB  1 
ATOM   5992  C CG  . LEU B 2 371 ? 112.598 98.126  58.033  1.00 431.57 ? 371 LEU B CG  1 
ATOM   5993  C CD1 . LEU B 2 371 ? 112.445 99.504  57.389  1.00 424.32 ? 371 LEU B CD1 1 
ATOM   5994  C CD2 . LEU B 2 371 ? 114.010 97.575  57.815  1.00 473.89 ? 371 LEU B CD2 1 
ATOM   5995  N N   . THR B 2 372 ? 112.791 99.874  62.806  1.00 256.97 ? 372 THR B N   1 
ATOM   5996  C CA  . THR B 2 372 ? 112.322 99.994  64.187  1.00 225.87 ? 372 THR B CA  1 
ATOM   5997  C C   . THR B 2 372 ? 111.954 101.447 64.502  1.00 146.54 ? 372 THR B C   1 
ATOM   5998  O O   . THR B 2 372 ? 112.616 102.366 64.027  1.00 188.86 ? 372 THR B O   1 
ATOM   5999  C CB  . THR B 2 372 ? 113.374 99.497  65.177  1.00 247.54 ? 372 THR B CB  1 
ATOM   6000  O OG1 . THR B 2 372 ? 114.550 100.278 64.969  1.00 228.93 ? 372 THR B OG1 1 
ATOM   6001  C CG2 . THR B 2 372 ? 113.707 98.025  65.018  1.00 192.68 ? 372 THR B CG2 1 
ATOM   6002  N N   . PRO B 2 373 ? 110.844 101.708 65.232  1.00 132.31 ? 373 PRO B N   1 
ATOM   6003  C CA  . PRO B 2 373 ? 110.232 103.044 65.280  1.00 157.37 ? 373 PRO B CA  1 
ATOM   6004  C C   . PRO B 2 373 ? 110.803 103.983 66.331  1.00 146.27 ? 373 PRO B C   1 
ATOM   6005  O O   . PRO B 2 373 ? 110.049 104.538 67.131  1.00 107.76 ? 373 PRO B O   1 
ATOM   6006  C CB  . PRO B 2 373 ? 108.751 102.690 65.524  1.00 183.88 ? 373 PRO B CB  1 
ATOM   6007  C CG  . PRO B 2 373 ? 108.860 101.531 66.466  1.00 181.57 ? 373 PRO B CG  1 
ATOM   6008  C CD  . PRO B 2 373 ? 110.048 100.724 65.977  1.00 165.01 ? 373 PRO B CD  1 
ATOM   6009  N N   . VAL B 2 374 ? 112.127 104.177 66.248  1.00 126.32 ? 374 VAL B N   1 
ATOM   6010  C CA  . VAL B 2 374 ? 112.964 104.748 67.300  1.00 159.57 ? 374 VAL B CA  1 
ATOM   6011  C C   . VAL B 2 374 ? 112.385 105.949 68.068  1.00 158.46 ? 374 VAL B C   1 
ATOM   6012  O O   . VAL B 2 374 ? 112.357 105.856 69.299  1.00 258.24 ? 374 VAL B O   1 
ATOM   6013  C CB  . VAL B 2 374 ? 114.352 105.017 66.707  1.00 174.00 ? 374 VAL B CB  1 
ATOM   6014  C CG1 . VAL B 2 374 ? 115.215 106.029 67.479  1.00 175.39 ? 374 VAL B CG1 1 
ATOM   6015  C CG2 . VAL B 2 374 ? 115.041 103.657 66.536  1.00 163.14 ? 374 VAL B CG2 1 
ATOM   6016  N N   . PRO B 2 375 ? 111.904 107.068 67.504  1.00 127.25 ? 375 PRO B N   1 
ATOM   6017  C CA  . PRO B 2 375 ? 111.384 108.162 68.332  1.00 159.40 ? 375 PRO B CA  1 
ATOM   6018  C C   . PRO B 2 375 ? 110.156 107.800 69.178  1.00 182.96 ? 375 PRO B C   1 
ATOM   6019  O O   . PRO B 2 375 ? 110.009 108.383 70.256  1.00 253.85 ? 375 PRO B O   1 
ATOM   6020  C CB  . PRO B 2 375 ? 111.027 109.273 67.340  1.00 217.33 ? 375 PRO B CB  1 
ATOM   6021  C CG  . PRO B 2 375 ? 111.769 108.872 66.075  1.00 268.34 ? 375 PRO B CG  1 
ATOM   6022  C CD  . PRO B 2 375 ? 111.793 107.351 66.085  1.00 189.70 ? 375 PRO B CD  1 
ATOM   6023  N N   . SER B 2 376 ? 109.307 106.853 68.731  1.00 164.37 ? 376 SER B N   1 
ATOM   6024  C CA  . SER B 2 376 ? 108.163 106.411 69.528  1.00 214.02 ? 376 SER B CA  1 
ATOM   6025  C C   . SER B 2 376 ? 108.596 105.588 70.750  1.00 194.57 ? 376 SER B C   1 
ATOM   6026  O O   . SER B 2 376 ? 108.028 105.725 71.829  1.00 133.64 ? 376 SER B O   1 
ATOM   6027  C CB  . SER B 2 376 ? 107.167 105.622 68.696  1.00 223.71 ? 376 SER B CB  1 
ATOM   6028  O OG  . SER B 2 376 ? 107.676 104.354 68.293  1.00 145.28 ? 376 SER B OG  1 
ATOM   6029  N N   . LEU B 2 377 ? 109.601 104.714 70.581  1.00 161.05 ? 377 LEU B N   1 
ATOM   6030  C CA  . LEU B 2 377 ? 110.136 103.918 71.667  1.00 142.02 ? 377 LEU B CA  1 
ATOM   6031  C C   . LEU B 2 377 ? 110.785 104.842 72.674  1.00 116.33 ? 377 LEU B C   1 
ATOM   6032  O O   . LEU B 2 377 ? 110.501 104.748 73.861  1.00 153.76 ? 377 LEU B O   1 
ATOM   6033  C CB  . LEU B 2 377 ? 111.129 102.863 71.140  1.00 145.75 ? 377 LEU B CB  1 
ATOM   6034  C CG  . LEU B 2 377 ? 110.482 101.736 70.325  1.00 169.76 ? 377 LEU B CG  1 
ATOM   6035  C CD1 . LEU B 2 377 ? 111.520 100.727 69.901  1.00 197.77 ? 377 LEU B CD1 1 
ATOM   6036  C CD2 . LEU B 2 377 ? 109.368 100.978 71.051  1.00 166.85 ? 377 LEU B CD2 1 
ATOM   6037  N N   . VAL B 2 378 ? 111.669 105.719 72.224  1.00 127.68 ? 378 VAL B N   1 
ATOM   6038  C CA  . VAL B 2 378 ? 112.326 106.627 73.146  1.00 137.27 ? 378 VAL B CA  1 
ATOM   6039  C C   . VAL B 2 378 ? 111.335 107.509 73.898  1.00 123.77 ? 378 VAL B C   1 
ATOM   6040  O O   . VAL B 2 378 ? 111.590 107.770 75.074  1.00 250.20 ? 378 VAL B O   1 
ATOM   6041  C CB  . VAL B 2 378 ? 113.392 107.434 72.418  1.00 197.92 ? 378 VAL B CB  1 
ATOM   6042  C CG1 . VAL B 2 378 ? 113.823 108.699 73.177  1.00 215.40 ? 378 VAL B CG1 1 
ATOM   6043  C CG2 . VAL B 2 378 ? 114.558 106.483 72.107  1.00 204.96 ? 378 VAL B CG2 1 
ATOM   6044  N N   . PHE B 2 379 ? 110.233 107.940 73.304  1.00 119.31 ? 379 PHE B N   1 
ATOM   6045  C CA  . PHE B 2 379 ? 109.231 108.684 74.062  1.00 182.43 ? 379 PHE B CA  1 
ATOM   6046  C C   . PHE B 2 379 ? 108.517 107.770 75.059  1.00 154.82 ? 379 PHE B C   1 
ATOM   6047  O O   . PHE B 2 379 ? 108.326 108.170 76.208  1.00 126.52 ? 379 PHE B O   1 
ATOM   6048  C CB  . PHE B 2 379 ? 108.225 109.374 73.141  1.00 200.47 ? 379 PHE B CB  1 
ATOM   6049  C CG  . PHE B 2 379 ? 107.121 110.100 73.866  1.00 189.72 ? 379 PHE B CG  1 
ATOM   6050  C CD1 . PHE B 2 379 ? 107.296 111.384 74.385  1.00 235.63 ? 379 PHE B CD1 1 
ATOM   6051  C CD2 . PHE B 2 379 ? 105.898 109.478 74.041  1.00 177.24 ? 379 PHE B CD2 1 
ATOM   6052  C CE1 . PHE B 2 379 ? 106.256 112.019 75.052  1.00 257.24 ? 379 PHE B CE1 1 
ATOM   6053  C CE2 . PHE B 2 379 ? 104.856 110.115 74.708  1.00 196.84 ? 379 PHE B CE2 1 
ATOM   6054  C CZ  . PHE B 2 379 ? 105.037 111.381 75.214  1.00 209.98 ? 379 PHE B CZ  1 
ATOM   6055  N N   . THR B 2 380 ? 108.116 106.564 74.630  1.00 135.21 ? 380 THR B N   1 
ATOM   6056  C CA  . THR B 2 380 ? 107.469 105.606 75.527  1.00 183.80 ? 380 THR B CA  1 
ATOM   6057  C C   . THR B 2 380 ? 108.320 105.360 76.770  1.00 157.08 ? 380 THR B C   1 
ATOM   6058  O O   . THR B 2 380 ? 107.844 105.416 77.905  1.00 157.34 ? 380 THR B O   1 
ATOM   6059  C CB  . THR B 2 380 ? 107.197 104.257 74.848  1.00 187.48 ? 380 THR B CB  1 
ATOM   6060  O OG1 . THR B 2 380 ? 106.309 104.515 73.769  1.00 265.85 ? 380 THR B OG1 1 
ATOM   6061  C CG2 . THR B 2 380 ? 106.557 103.227 75.755  1.00 215.30 ? 380 THR B CG2 1 
ATOM   6062  N N   . CYS B 2 381 ? 109.587 105.076 76.508  1.00 138.79 ? 381 CYS B N   1 
ATOM   6063  C CA  . CYS B 2 381 ? 110.562 104.780 77.523  1.00 142.46 ? 381 CYS B CA  1 
ATOM   6064  C C   . CYS B 2 381 ? 110.737 105.924 78.524  1.00 110.28 ? 381 CYS B C   1 
ATOM   6065  O O   . CYS B 2 381 ? 110.666 105.726 79.725  1.00 131.04 ? 381 CYS B O   1 
ATOM   6066  C CB  . CYS B 2 381 ? 111.878 104.508 76.829  1.00 154.79 ? 381 CYS B CB  1 
ATOM   6067  S SG  . CYS B 2 381 ? 113.220 104.225 78.016  1.00 187.02 ? 381 CYS B SG  1 
ATOM   6068  N N   . VAL B 2 382 ? 110.994 107.121 78.060  1.00 109.97 ? 382 VAL B N   1 
ATOM   6069  C CA  . VAL B 2 382 ? 111.205 108.223 78.974  1.00 160.14 ? 382 VAL B CA  1 
ATOM   6070  C C   . VAL B 2 382 ? 109.932 108.542 79.754  1.00 156.29 ? 382 VAL B C   1 
ATOM   6071  O O   . VAL B 2 382 ? 110.076 108.972 80.889  1.00 187.47 ? 382 VAL B O   1 
ATOM   6072  C CB  . VAL B 2 382 ? 111.807 109.415 78.225  1.00 242.50 ? 382 VAL B CB  1 
ATOM   6073  C CG1 . VAL B 2 382 ? 111.613 110.767 78.917  1.00 310.33 ? 382 VAL B CG1 1 
ATOM   6074  C CG2 . VAL B 2 382 ? 113.282 109.093 77.969  1.00 229.22 ? 382 VAL B CG2 1 
ATOM   6075  N N   . MET B 2 383 ? 108.730 108.319 79.221  1.00 116.46 ? 383 MET B N   1 
ATOM   6076  C CA  . MET B 2 383 ? 107.563 108.448 80.090  1.00 144.27 ? 383 MET B CA  1 
ATOM   6077  C C   . MET B 2 383 ? 107.530 107.370 81.187  1.00 149.86 ? 383 MET B C   1 
ATOM   6078  O O   . MET B 2 383 ? 107.305 107.671 82.347  1.00 150.90 ? 383 MET B O   1 
ATOM   6079  C CB  . MET B 2 383 ? 106.257 108.387 79.304  1.00 168.01 ? 383 MET B CB  1 
ATOM   6080  C CG  . MET B 2 383 ? 106.006 109.634 78.481  1.00 200.40 ? 383 MET B CG  1 
ATOM   6081  S SD  . MET B 2 383 ? 106.190 111.204 79.365  1.00 335.82 ? 383 MET B SD  1 
ATOM   6082  C CE  . MET B 2 383 ? 105.142 110.938 80.796  1.00 367.01 ? 383 MET B CE  1 
ATOM   6083  N N   . THR B 2 384 ? 107.762 106.110 80.850  1.00 144.28 ? 384 THR B N   1 
ATOM   6084  C CA  . THR B 2 384 ? 107.881 105.061 81.857  1.00 144.72 ? 384 THR B CA  1 
ATOM   6085  C C   . THR B 2 384 ? 108.909 105.414 82.938  1.00 113.89 ? 384 THR B C   1 
ATOM   6086  O O   . THR B 2 384 ? 108.642 105.187 84.102  1.00 121.40 ? 384 THR B O   1 
ATOM   6087  C CB  . THR B 2 384 ? 108.220 103.715 81.184  1.00 164.73 ? 384 THR B CB  1 
ATOM   6088  O OG1 . THR B 2 384 ? 107.119 103.443 80.314  1.00 194.79 ? 384 THR B OG1 1 
ATOM   6089  C CG2 . THR B 2 384 ? 108.441 102.541 82.122  1.00 133.23 ? 384 THR B CG2 1 
ATOM   6090  N N   . LEU B 2 385 ? 110.086 105.937 82.571  1.00 98.20  ? 385 LEU B N   1 
ATOM   6091  C CA  . LEU B 2 385 ? 111.141 106.204 83.539  1.00 111.71 ? 385 LEU B CA  1 
ATOM   6092  C C   . LEU B 2 385 ? 110.838 107.359 84.475  1.00 122.40 ? 385 LEU B C   1 
ATOM   6093  O O   . LEU B 2 385 ? 111.495 107.456 85.499  1.00 147.36 ? 385 LEU B O   1 
ATOM   6094  C CB  . LEU B 2 385 ? 112.459 106.481 82.827  1.00 132.40 ? 385 LEU B CB  1 
ATOM   6095  C CG  . LEU B 2 385 ? 113.498 105.384 83.016  1.00 189.16 ? 385 LEU B CG  1 
ATOM   6096  C CD1 . LEU B 2 385 ? 112.968 104.031 82.553  1.00 155.99 ? 385 LEU B CD1 1 
ATOM   6097  C CD2 . LEU B 2 385 ? 114.771 105.799 82.310  1.00 257.58 ? 385 LEU B CD2 1 
ATOM   6098  N N   . LEU B 2 386 ? 109.880 108.223 84.157  1.00 127.17 ? 386 LEU B N   1 
ATOM   6099  C CA  . LEU B 2 386 ? 109.533 109.279 85.092  1.00 149.48 ? 386 LEU B CA  1 
ATOM   6100  C C   . LEU B 2 386 ? 108.715 108.764 86.278  1.00 161.61 ? 386 LEU B C   1 
ATOM   6101  O O   . LEU B 2 386 ? 108.681 109.424 87.327  1.00 214.73 ? 386 LEU B O   1 
ATOM   6102  C CB  . LEU B 2 386 ? 108.771 110.363 84.341  1.00 183.96 ? 386 LEU B CB  1 
ATOM   6103  C CG  . LEU B 2 386 ? 109.640 111.184 83.398  1.00 237.27 ? 386 LEU B CG  1 
ATOM   6104  C CD1 . LEU B 2 386 ? 108.761 112.089 82.548  1.00 296.36 ? 386 LEU B CD1 1 
ATOM   6105  C CD2 . LEU B 2 386 ? 110.689 111.992 84.181  1.00 324.00 ? 386 LEU B CD2 1 
ATOM   6106  N N   . TYR B 2 387 ? 108.067 107.600 86.140  1.00 112.90 ? 387 TYR B N   1 
ATOM   6107  C CA  . TYR B 2 387 ? 107.292 107.069 87.254  1.00 143.85 ? 387 TYR B CA  1 
ATOM   6108  C C   . TYR B 2 387 ? 108.189 106.578 88.391  1.00 123.78 ? 387 TYR B C   1 
ATOM   6109  O O   . TYR B 2 387 ? 107.661 106.337 89.473  1.00 145.80 ? 387 TYR B O   1 
ATOM   6110  C CB  . TYR B 2 387 ? 106.326 106.006 86.734  1.00 175.09 ? 387 TYR B CB  1 
ATOM   6111  C CG  . TYR B 2 387 ? 105.100 106.669 86.145  1.00 162.90 ? 387 TYR B CG  1 
ATOM   6112  C CD1 . TYR B 2 387 ? 105.163 107.329 84.942  1.00 181.42 ? 387 TYR B CD1 1 
ATOM   6113  C CD2 . TYR B 2 387 ? 103.897 106.659 86.820  1.00 147.59 ? 387 TYR B CD2 1 
ATOM   6114  C CE1 . TYR B 2 387 ? 104.052 107.954 84.409  1.00 245.08 ? 387 TYR B CE1 1 
ATOM   6115  C CE2 . TYR B 2 387 ? 102.780 107.271 86.295  1.00 183.29 ? 387 TYR B CE2 1 
ATOM   6116  C CZ  . TYR B 2 387 ? 102.851 107.926 85.084  1.00 216.56 ? 387 TYR B CZ  1 
ATOM   6117  O OH  . TYR B 2 387 ? 101.762 108.547 84.560  1.00 237.71 ? 387 TYR B OH  1 
ATOM   6118  N N   . ALA B 2 388 ? 109.506 106.473 88.180  1.00 107.11 ? 388 ALA B N   1 
ATOM   6119  C CA  . ALA B 2 388 ? 110.466 106.358 89.275  1.00 174.94 ? 388 ALA B CA  1 
ATOM   6120  C C   . ALA B 2 388 ? 110.366 107.465 90.341  1.00 174.90 ? 388 ALA B C   1 
ATOM   6121  O O   . ALA B 2 388 ? 110.858 107.258 91.452  1.00 198.21 ? 388 ALA B O   1 
ATOM   6122  C CB  . ALA B 2 388 ? 111.871 106.299 88.712  1.00 211.32 ? 388 ALA B CB  1 
ATOM   6123  N N   . PHE B 2 389 ? 109.745 108.613 90.030  1.00 162.78 ? 389 PHE B N   1 
ATOM   6124  C CA  . PHE B 2 389 ? 109.497 109.646 91.028  1.00 222.55 ? 389 PHE B CA  1 
ATOM   6125  C C   . PHE B 2 389 ? 108.297 109.346 91.941  1.00 205.77 ? 389 PHE B C   1 
ATOM   6126  O O   . PHE B 2 389 ? 108.106 110.049 92.935  1.00 247.62 ? 389 PHE B O   1 
ATOM   6127  C CB  . PHE B 2 389 ? 109.358 110.996 90.312  1.00 265.06 ? 389 PHE B CB  1 
ATOM   6128  C CG  . PHE B 2 389 ? 110.556 111.466 89.506  1.00 305.68 ? 389 PHE B CG  1 
ATOM   6129  C CD1 . PHE B 2 389 ? 111.854 110.990 89.738  1.00 293.39 ? 389 PHE B CD1 1 
ATOM   6130  C CD2 . PHE B 2 389 ? 110.378 112.410 88.496  1.00 319.11 ? 389 PHE B CD2 1 
ATOM   6131  C CE1 . PHE B 2 389 ? 112.927 111.443 88.982  1.00 296.04 ? 389 PHE B CE1 1 
ATOM   6132  C CE2 . PHE B 2 389 ? 111.451 112.863 87.736  1.00 318.25 ? 389 PHE B CE2 1 
ATOM   6133  C CZ  . PHE B 2 389 ? 112.723 112.380 87.985  1.00 347.29 ? 389 PHE B CZ  1 
ATOM   6134  N N   . SER B 2 390 ? 107.487 108.320 91.654  1.00 186.33 ? 390 SER B N   1 
ATOM   6135  C CA  . SER B 2 390 ? 106.364 107.948 92.517  1.00 189.06 ? 390 SER B CA  1 
ATOM   6136  C C   . SER B 2 390 ? 106.848 107.299 93.829  1.00 242.99 ? 390 SER B C   1 
ATOM   6137  O O   . SER B 2 390 ? 107.983 106.861 93.918  1.00 229.28 ? 390 SER B O   1 
ATOM   6138  C CB  . SER B 2 390 ? 105.429 107.036 91.757  1.00 209.82 ? 390 SER B CB  1 
ATOM   6139  O OG  . SER B 2 390 ? 106.074 105.805 91.453  1.00 244.41 ? 390 SER B OG  1 
ATOM   6140  N N   . LYS B 2 391 ? 105.996 107.220 94.868  1.00 286.52 ? 391 LYS B N   1 
ATOM   6141  C CA  . LYS B 2 391 ? 106.397 106.721 96.188  1.00 286.11 ? 391 LYS B CA  1 
ATOM   6142  C C   . LYS B 2 391 ? 106.400 105.187 96.298  1.00 271.59 ? 391 LYS B C   1 
ATOM   6143  O O   . LYS B 2 391 ? 107.386 104.614 96.751  1.00 257.01 ? 391 LYS B O   1 
ATOM   6144  C CB  . LYS B 2 391 ? 105.496 107.331 97.271  1.00 285.27 ? 391 LYS B CB  1 
ATOM   6145  C CG  . LYS B 2 391 ? 105.588 108.845 97.437  1.00 338.58 ? 391 LYS B CG  1 
ATOM   6146  C CD  . LYS B 2 391 ? 106.981 109.378 97.771  1.00 362.70 ? 391 LYS B CD  1 
ATOM   6147  C CE  . LYS B 2 391 ? 107.792 109.799 96.559  1.00 340.70 ? 391 LYS B CE  1 
ATOM   6148  N NZ  . LYS B 2 391 ? 109.163 110.233 96.931  1.00 280.15 ? 391 LYS B NZ  1 
ATOM   6149  N N   . ASP B 2 392 ? 105.311 104.517 95.896  1.00 272.87 ? 392 ASP B N   1 
ATOM   6150  C CA  . ASP B 2 392 ? 105.006 103.150 96.325  1.00 249.63 ? 392 ASP B CA  1 
ATOM   6151  C C   . ASP B 2 392 ? 104.197 102.427 95.247  1.00 187.24 ? 392 ASP B C   1 
ATOM   6152  O O   . ASP B 2 392 ? 103.350 103.062 94.613  1.00 158.39 ? 392 ASP B O   1 
ATOM   6153  C CB  . ASP B 2 392 ? 104.257 103.225 97.663  1.00 349.04 ? 392 ASP B CB  1 
ATOM   6154  C CG  . ASP B 2 392 ? 103.858 101.912 98.329  1.00 411.47 ? 392 ASP B CG  1 
ATOM   6155  O OD1 . ASP B 2 392 ? 104.383 100.855 97.930  1.00 433.95 ? 392 ASP B OD1 1 
ATOM   6156  O OD2 . ASP B 2 392 ? 103.009 101.959 99.247  1.00 448.89 ? 392 ASP B OD2 1 
ATOM   6157  N N   . ILE B 2 393 ? 104.429 101.110 95.047  1.00 138.02 ? 393 ILE B N   1 
ATOM   6158  C CA  . ILE B 2 393 ? 103.812 100.353 93.944  1.00 137.66 ? 393 ILE B CA  1 
ATOM   6159  C C   . ILE B 2 393 ? 102.273 100.371 93.967  1.00 150.91 ? 393 ILE B C   1 
ATOM   6160  O O   . ILE B 2 393 ? 101.643 100.560 92.918  1.00 186.15 ? 393 ILE B O   1 
ATOM   6161  C CB  . ILE B 2 393 ? 104.374 98.928  93.862  1.00 145.79 ? 393 ILE B CB  1 
ATOM   6162  C CG1 . ILE B 2 393 ? 104.089 98.257  92.518  1.00 175.99 ? 393 ILE B CG1 1 
ATOM   6163  C CG2 . ILE B 2 393 ? 103.903 98.047  94.999  1.00 206.33 ? 393 ILE B CG2 1 
ATOM   6164  C CD1 . ILE B 2 393 ? 104.989 97.018  92.270  1.00 191.65 ? 393 ILE B CD1 1 
ATOM   6165  N N   . PHE B 2 394 ? 101.654 100.229 95.143  1.00 168.43 ? 394 PHE B N   1 
ATOM   6166  C CA  . PHE B 2 394 ? 100.202 100.297 95.222  1.00 199.10 ? 394 PHE B CA  1 
ATOM   6167  C C   . PHE B 2 394 ? 99.683  101.727 95.098  1.00 165.86 ? 394 PHE B C   1 
ATOM   6168  O O   . PHE B 2 394 ? 98.478  101.871 94.896  1.00 198.64 ? 394 PHE B O   1 
ATOM   6169  C CB  . PHE B 2 394 ? 99.697  99.603  96.493  1.00 241.55 ? 394 PHE B CB  1 
ATOM   6170  C CG  . PHE B 2 394 ? 99.962  98.127  96.420  1.00 204.72 ? 394 PHE B CG  1 
ATOM   6171  C CD1 . PHE B 2 394 ? 99.231  97.328  95.554  1.00 192.12 ? 394 PHE B CD1 1 
ATOM   6172  C CD2 . PHE B 2 394 ? 100.968 97.551  97.180  1.00 240.90 ? 394 PHE B CD2 1 
ATOM   6173  C CE1 . PHE B 2 394 ? 99.492  95.972  95.465  1.00 221.88 ? 394 PHE B CE1 1 
ATOM   6174  C CE2 . PHE B 2 394 ? 101.229 96.190  97.093  1.00 260.54 ? 394 PHE B CE2 1 
ATOM   6175  C CZ  . PHE B 2 394 ? 100.496 95.405  96.230  1.00 250.34 ? 394 PHE B CZ  1 
ATOM   6176  N N   . SER B 2 395 ? 100.545 102.756 95.226  1.00 166.96 ? 395 SER B N   1 
ATOM   6177  C CA  . SER B 2 395 ? 100.145 104.122 94.897  1.00 240.59 ? 395 SER B CA  1 
ATOM   6178  C C   . SER B 2 395 ? 99.907  104.200 93.387  1.00 199.69 ? 395 SER B C   1 
ATOM   6179  O O   . SER B 2 395 ? 98.867  104.680 92.903  1.00 195.61 ? 395 SER B O   1 
ATOM   6180  C CB  . SER B 2 395 ? 101.147 105.168 95.386  1.00 256.55 ? 395 SER B CB  1 
ATOM   6181  O OG  . SER B 2 395 ? 100.491 106.351 95.824  1.00 353.09 ? 395 SER B OG  1 
ATOM   6182  N N   . VAL B 2 396 ? 100.875 103.676 92.642  1.00 159.94 ? 396 VAL B N   1 
ATOM   6183  C CA  . VAL B 2 396 ? 100.812 103.739 91.200  1.00 162.86 ? 396 VAL B CA  1 
ATOM   6184  C C   . VAL B 2 396 ? 99.697  102.825 90.682  1.00 169.37 ? 396 VAL B C   1 
ATOM   6185  O O   . VAL B 2 396 ? 99.087  103.170 89.657  1.00 207.32 ? 396 VAL B O   1 
ATOM   6186  C CB  . VAL B 2 396 ? 102.198 103.442 90.593  1.00 148.88 ? 396 VAL B CB  1 
ATOM   6187  C CG1 . VAL B 2 396 ? 102.207 103.604 89.085  1.00 185.71 ? 396 VAL B CG1 1 
ATOM   6188  C CG2 . VAL B 2 396 ? 103.238 104.349 91.190  1.00 173.79 ? 396 VAL B CG2 1 
ATOM   6189  N N   . ILE B 2 397 ? 99.409  101.678 91.331  1.00 133.28 ? 397 ILE B N   1 
ATOM   6190  C CA  . ILE B 2 397 ? 98.324  100.832 90.846  1.00 146.30 ? 397 ILE B CA  1 
ATOM   6191  C C   . ILE B 2 397 ? 97.000  101.577 91.020  1.00 143.45 ? 397 ILE B C   1 
ATOM   6192  O O   . ILE B 2 397 ? 96.120  101.452 90.163  1.00 117.53 ? 397 ILE B O   1 
ATOM   6193  C CB  . ILE B 2 397 ? 98.365  99.414  91.464  1.00 148.36 ? 397 ILE B CB  1 
ATOM   6194  C CG1 . ILE B 2 397 ? 99.474  98.585  90.822  1.00 135.51 ? 397 ILE B CG1 1 
ATOM   6195  C CG2 . ILE B 2 397 ? 97.062  98.628  91.361  1.00 138.42 ? 397 ILE B CG2 1 
ATOM   6196  C CD1 . ILE B 2 397 ? 99.794  97.300  91.550  1.00 154.34 ? 397 ILE B CD1 1 
ATOM   6197  N N   . ASN B 2 398 ? 96.846  102.342 92.104  1.00 143.27 ? 398 ASN B N   1 
ATOM   6198  C CA  . ASN B 2 398 ? 95.610  103.091 92.298  1.00 207.19 ? 398 ASN B CA  1 
ATOM   6199  C C   . ASN B 2 398 ? 95.485  104.145 91.200  1.00 192.73 ? 398 ASN B C   1 
ATOM   6200  O O   . ASN B 2 398 ? 94.404  104.313 90.613  1.00 190.99 ? 398 ASN B O   1 
ATOM   6201  C CB  . ASN B 2 398 ? 95.520  103.636 93.727  1.00 222.39 ? 398 ASN B CB  1 
ATOM   6202  C CG  . ASN B 2 398 ? 95.265  102.553 94.770  1.00 262.22 ? 398 ASN B CG  1 
ATOM   6203  O OD1 . ASN B 2 398 ? 94.860  101.425 94.472  1.00 219.72 ? 398 ASN B OD1 1 
ATOM   6204  N ND2 . ASN B 2 398 ? 95.497  102.885 96.028  1.00 336.18 ? 398 ASN B ND2 1 
ATOM   6205  N N   . PHE B 2 399 ? 96.594  104.839 90.932  1.00 175.10 ? 399 PHE B N   1 
ATOM   6206  C CA  . PHE B 2 399 ? 96.628  105.875 89.911  1.00 195.25 ? 399 PHE B CA  1 
ATOM   6207  C C   . PHE B 2 399 ? 96.279  105.335 88.526  1.00 154.00 ? 399 PHE B C   1 
ATOM   6208  O O   . PHE B 2 399 ? 95.360  105.851 87.885  1.00 170.89 ? 399 PHE B O   1 
ATOM   6209  C CB  . PHE B 2 399 ? 98.013  106.503 89.922  1.00 208.05 ? 399 PHE B CB  1 
ATOM   6210  C CG  . PHE B 2 399 ? 98.227  107.582 88.903  1.00 159.69 ? 399 PHE B CG  1 
ATOM   6211  C CD1 . PHE B 2 399 ? 97.711  108.845 89.090  1.00 177.99 ? 399 PHE B CD1 1 
ATOM   6212  C CD2 . PHE B 2 399 ? 98.948  107.321 87.761  1.00 194.23 ? 399 PHE B CD2 1 
ATOM   6213  C CE1 . PHE B 2 399 ? 97.926  109.834 88.149  1.00 258.97 ? 399 PHE B CE1 1 
ATOM   6214  C CE2 . PHE B 2 399 ? 99.158  108.309 86.818  1.00 230.39 ? 399 PHE B CE2 1 
ATOM   6215  C CZ  . PHE B 2 399 ? 98.649  109.564 87.015  1.00 246.72 ? 399 PHE B CZ  1 
ATOM   6216  N N   . PHE B 2 400 ? 97.008  104.308 88.078  1.00 130.01 ? 400 PHE B N   1 
ATOM   6217  C CA  . PHE B 2 400 ? 96.691  103.600 86.842  1.00 155.43 ? 400 PHE B CA  1 
ATOM   6218  C C   . PHE B 2 400 ? 95.209  103.208 86.786  1.00 152.98 ? 400 PHE B C   1 
ATOM   6219  O O   . PHE B 2 400 ? 94.549  103.464 85.770  1.00 167.92 ? 400 PHE B O   1 
ATOM   6220  C CB  . PHE B 2 400 ? 97.589  102.372 86.696  1.00 171.68 ? 400 PHE B CB  1 
ATOM   6221  C CG  . PHE B 2 400 ? 97.080  101.340 85.729  1.00 138.15 ? 400 PHE B CG  1 
ATOM   6222  C CD1 . PHE B 2 400 ? 97.495  101.358 84.422  1.00 165.96 ? 400 PHE B CD1 1 
ATOM   6223  C CD2 . PHE B 2 400 ? 96.197  100.344 86.135  1.00 165.46 ? 400 PHE B CD2 1 
ATOM   6224  C CE1 . PHE B 2 400 ? 97.021  100.410 83.520  1.00 264.78 ? 400 PHE B CE1 1 
ATOM   6225  C CE2 . PHE B 2 400 ? 95.735  99.386  85.245  1.00 216.00 ? 400 PHE B CE2 1 
ATOM   6226  C CZ  . PHE B 2 400 ? 96.150  99.418  83.933  1.00 250.38 ? 400 PHE B CZ  1 
ATOM   6227  N N   . SER B 2 401 ? 94.692  102.604 87.875  1.00 132.04 ? 401 SER B N   1 
ATOM   6228  C CA  . SER B 2 401 ? 93.348  102.040 87.860  1.00 189.26 ? 401 SER B CA  1 
ATOM   6229  C C   . SER B 2 401 ? 92.279  103.117 87.674  1.00 220.58 ? 401 SER B C   1 
ATOM   6230  O O   . SER B 2 401 ? 91.338  102.925 86.893  1.00 172.81 ? 401 SER B O   1 
ATOM   6231  C CB  . SER B 2 401 ? 93.078  101.244 89.088  1.00 181.83 ? 401 SER B CB  1 
ATOM   6232  O OG  . SER B 2 401 ? 93.945  100.134 89.131  1.00 179.80 ? 401 SER B OG  1 
ATOM   6233  N N   . PHE B 2 402 ? 92.426  104.249 88.368  1.00 193.62 ? 402 PHE B N   1 
ATOM   6234  C CA  . PHE B 2 402 ? 91.464  105.330 88.216  1.00 196.15 ? 402 PHE B CA  1 
ATOM   6235  C C   . PHE B 2 402 ? 91.300  105.711 86.737  1.00 173.06 ? 402 PHE B C   1 
ATOM   6236  O O   . PHE B 2 402 ? 90.192  105.665 86.191  1.00 143.35 ? 402 PHE B O   1 
ATOM   6237  C CB  . PHE B 2 402 ? 91.853  106.511 89.109  1.00 208.89 ? 402 PHE B CB  1 
ATOM   6238  C CG  . PHE B 2 402 ? 90.838  107.623 89.061  1.00 244.40 ? 402 PHE B CG  1 
ATOM   6239  C CD1 . PHE B 2 402 ? 90.953  108.633 88.117  1.00 210.97 ? 402 PHE B CD1 1 
ATOM   6240  C CD2 . PHE B 2 402 ? 89.751  107.643 89.931  1.00 304.74 ? 402 PHE B CD2 1 
ATOM   6241  C CE1 . PHE B 2 402 ? 90.025  109.663 88.048  1.00 212.50 ? 402 PHE B CE1 1 
ATOM   6242  C CE2 . PHE B 2 402 ? 88.816  108.670 89.863  1.00 341.37 ? 402 PHE B CE2 1 
ATOM   6243  C CZ  . PHE B 2 402 ? 88.953  109.679 88.921  1.00 301.91 ? 402 PHE B CZ  1 
ATOM   6244  N N   . PHE B 2 403 ? 92.402  106.078 86.078  1.00 156.24 ? 403 PHE B N   1 
ATOM   6245  C CA  . PHE B 2 403 ? 92.315  106.544 84.702  1.00 151.63 ? 403 PHE B CA  1 
ATOM   6246  C C   . PHE B 2 403 ? 91.996  105.410 83.736  1.00 150.55 ? 403 PHE B C   1 
ATOM   6247  O O   . PHE B 2 403 ? 91.329  105.691 82.738  1.00 220.43 ? 403 PHE B O   1 
ATOM   6248  C CB  . PHE B 2 403 ? 93.569  107.333 84.323  1.00 160.34 ? 403 PHE B CB  1 
ATOM   6249  C CG  . PHE B 2 403 ? 93.614  108.564 85.169  1.00 172.27 ? 403 PHE B CG  1 
ATOM   6250  C CD1 . PHE B 2 403 ? 92.769  109.605 84.855  1.00 222.91 ? 403 PHE B CD1 1 
ATOM   6251  C CD2 . PHE B 2 403 ? 94.438  108.655 86.287  1.00 182.41 ? 403 PHE B CD2 1 
ATOM   6252  C CE1 . PHE B 2 403 ? 92.766  110.745 85.638  1.00 293.59 ? 403 PHE B CE1 1 
ATOM   6253  C CE2 . PHE B 2 403 ? 94.435  109.797 87.066  1.00 192.34 ? 403 PHE B CE2 1 
ATOM   6254  C CZ  . PHE B 2 403 ? 93.592  110.830 86.737  1.00 257.30 ? 403 PHE B CZ  1 
ATOM   6255  N N   . ASN B 2 404 ? 92.461  104.176 83.986  1.00 143.38 ? 404 ASN B N   1 
ATOM   6256  C CA  . ASN B 2 404 ? 92.121  103.053 83.132  1.00 166.04 ? 404 ASN B CA  1 
ATOM   6257  C C   . ASN B 2 404 ? 90.602  102.850 83.115  1.00 185.74 ? 404 ASN B C   1 
ATOM   6258  O O   . ASN B 2 404 ? 90.008  102.771 82.019  1.00 238.69 ? 404 ASN B O   1 
ATOM   6259  C CB  . ASN B 2 404 ? 92.903  101.808 83.526  1.00 155.79 ? 404 ASN B CB  1 
ATOM   6260  C CG  . ASN B 2 404 ? 92.619  100.657 82.581  1.00 200.58 ? 404 ASN B CG  1 
ATOM   6261  O OD1 . ASN B 2 404 ? 92.932  100.768 81.391  1.00 164.80 ? 404 ASN B OD1 1 
ATOM   6262  N ND2 . ASN B 2 404 ? 92.021  99.571  83.090  1.00 247.55 ? 404 ASN B ND2 1 
ATOM   6263  N N   . TRP B 2 405 ? 89.972  102.780 84.305  1.00 142.11 ? 405 TRP B N   1 
ATOM   6264  C CA  . TRP B 2 405 ? 88.530  102.518 84.351  1.00 209.58 ? 405 TRP B CA  1 
ATOM   6265  C C   . TRP B 2 405 ? 87.712  103.742 83.905  1.00 227.35 ? 405 TRP B C   1 
ATOM   6266  O O   . TRP B 2 405 ? 86.614  103.567 83.352  1.00 140.30 ? 405 TRP B O   1 
ATOM   6267  C CB  . TRP B 2 405 ? 88.092  101.935 85.716  1.00 189.00 ? 405 TRP B CB  1 
ATOM   6268  C CG  . TRP B 2 405 ? 88.907  100.708 85.994  1.00 201.73 ? 405 TRP B CG  1 
ATOM   6269  C CD1 . TRP B 2 405 ? 89.734  100.505 87.056  1.00 295.92 ? 405 TRP B CD1 1 
ATOM   6270  C CD2 . TRP B 2 405 ? 89.031  99.531  85.162  1.00 211.26 ? 405 TRP B CD2 1 
ATOM   6271  N NE1 . TRP B 2 405 ? 90.351  99.287  86.963  1.00 320.76 ? 405 TRP B NE1 1 
ATOM   6272  C CE2 . TRP B 2 405 ? 89.945  98.666  85.808  1.00 295.81 ? 405 TRP B CE2 1 
ATOM   6273  C CE3 . TRP B 2 405 ? 88.471  99.112  83.949  1.00 217.99 ? 405 TRP B CE3 1 
ATOM   6274  C CZ2 . TRP B 2 405 ? 90.301  97.422  85.278  1.00 307.28 ? 405 TRP B CZ2 1 
ATOM   6275  C CZ3 . TRP B 2 405 ? 88.834  97.890  83.431  1.00 266.42 ? 405 TRP B CZ3 1 
ATOM   6276  C CH2 . TRP B 2 405 ? 89.736  97.054  84.084  1.00 266.92 ? 405 TRP B CH2 1 
ATOM   6277  N N   . LEU B 2 406 ? 88.241  104.961 84.116  1.00 213.49 ? 406 LEU B N   1 
ATOM   6278  C CA  . LEU B 2 406 ? 87.611  106.172 83.609  1.00 211.25 ? 406 LEU B CA  1 
ATOM   6279  C C   . LEU B 2 406 ? 87.636  106.191 82.078  1.00 184.27 ? 406 LEU B C   1 
ATOM   6280  O O   . LEU B 2 406 ? 86.656  106.631 81.476  1.00 228.37 ? 406 LEU B O   1 
ATOM   6281  C CB  . LEU B 2 406 ? 88.304  107.375 84.255  1.00 220.91 ? 406 LEU B CB  1 
ATOM   6282  C CG  . LEU B 2 406 ? 87.906  108.752 83.737  1.00 269.01 ? 406 LEU B CG  1 
ATOM   6283  C CD1 . LEU B 2 406 ? 87.818  109.746 84.881  1.00 287.22 ? 406 LEU B CD1 1 
ATOM   6284  C CD2 . LEU B 2 406 ? 88.895  109.237 82.678  1.00 261.61 ? 406 LEU B CD2 1 
ATOM   6285  N N   . CYS B 2 407 ? 88.716  105.719 81.440  1.00 164.54 ? 407 CYS B N   1 
ATOM   6286  C CA  . CYS B 2 407 ? 88.726  105.535 79.991  1.00 206.76 ? 407 CYS B CA  1 
ATOM   6287  C C   . CYS B 2 407 ? 87.726  104.479 79.507  1.00 209.80 ? 407 CYS B C   1 
ATOM   6288  O O   . CYS B 2 407 ? 87.008  104.719 78.522  1.00 274.68 ? 407 CYS B O   1 
ATOM   6289  C CB  . CYS B 2 407 ? 90.135  105.237 79.508  1.00 228.12 ? 407 CYS B CB  1 
ATOM   6290  S SG  . CYS B 2 407 ? 91.079  106.778 79.356  1.00 253.48 ? 407 CYS B SG  1 
ATOM   6291  N N   . VAL B 2 408 ? 87.654  103.333 80.192  1.00 176.81 ? 408 VAL B N   1 
ATOM   6292  C CA  . VAL B 2 408 ? 86.685  102.307 79.820  1.00 196.06 ? 408 VAL B CA  1 
ATOM   6293  C C   . VAL B 2 408 ? 85.244  102.824 80.012  1.00 212.05 ? 408 VAL B C   1 
ATOM   6294  O O   . VAL B 2 408 ? 84.352  102.483 79.227  1.00 206.38 ? 408 VAL B O   1 
ATOM   6295  C CB  . VAL B 2 408 ? 86.979  100.991 80.570  1.00 225.34 ? 408 VAL B CB  1 
ATOM   6296  C CG1 . VAL B 2 408 ? 85.888  99.943  80.424  1.00 263.78 ? 408 VAL B CG1 1 
ATOM   6297  C CG2 . VAL B 2 408 ? 88.293  100.403 80.102  1.00 266.61 ? 408 VAL B CG2 1 
ATOM   6298  N N   . ALA B 2 409 ? 84.993  103.655 81.036  1.00 205.61 ? 409 ALA B N   1 
ATOM   6299  C CA  . ALA B 2 409 ? 83.701  104.317 81.186  1.00 246.23 ? 409 ALA B CA  1 
ATOM   6300  C C   . ALA B 2 409 ? 83.325  105.126 79.932  1.00 224.05 ? 409 ALA B C   1 
ATOM   6301  O O   . ALA B 2 409 ? 82.243  104.926 79.379  1.00 173.41 ? 409 ALA B O   1 
ATOM   6302  C CB  . ALA B 2 409 ? 83.705  105.178 82.432  1.00 258.36 ? 409 ALA B CB  1 
ATOM   6303  N N   . LEU B 2 410 ? 84.207  106.029 79.478  1.00 200.00 ? 410 LEU B N   1 
ATOM   6304  C CA  . LEU B 2 410 ? 83.965  106.829 78.281  1.00 196.31 ? 410 LEU B CA  1 
ATOM   6305  C C   . LEU B 2 410 ? 83.697  105.960 77.040  1.00 208.25 ? 410 LEU B C   1 
ATOM   6306  O O   . LEU B 2 410 ? 82.903  106.356 76.184  1.00 253.17 ? 410 LEU B O   1 
ATOM   6307  C CB  . LEU B 2 410 ? 85.173  107.741 78.025  1.00 236.28 ? 410 LEU B CB  1 
ATOM   6308  C CG  . LEU B 2 410 ? 85.417  108.878 79.015  1.00 303.24 ? 410 LEU B CG  1 
ATOM   6309  C CD1 . LEU B 2 410 ? 86.733  109.574 78.695  1.00 320.08 ? 410 LEU B CD1 1 
ATOM   6310  C CD2 . LEU B 2 410 ? 84.280  109.891 79.016  1.00 337.47 ? 410 LEU B CD2 1 
ATOM   6311  N N   . ALA B 2 411 ? 84.356  104.794 76.934  1.00 227.58 ? 411 ALA B N   1 
ATOM   6312  C CA  . ALA B 2 411 ? 84.146  103.875 75.824  1.00 243.05 ? 411 ALA B CA  1 
ATOM   6313  C C   . ALA B 2 411 ? 82.755  103.233 75.871  1.00 243.05 ? 411 ALA B C   1 
ATOM   6314  O O   . ALA B 2 411 ? 82.041  103.259 74.863  1.00 300.94 ? 411 ALA B O   1 
ATOM   6315  C CB  . ALA B 2 411 ? 85.233  102.832 75.821  1.00 283.12 ? 411 ALA B CB  1 
ATOM   6316  N N   . ILE B 2 412 ? 82.351  102.666 77.021  1.00 221.50 ? 412 ILE B N   1 
ATOM   6317  C CA  . ILE B 2 412 ? 81.096  101.916 77.087  1.00 246.20 ? 412 ILE B CA  1 
ATOM   6318  C C   . ILE B 2 412 ? 79.889  102.868 77.151  1.00 255.27 ? 412 ILE B C   1 
ATOM   6319  O O   . ILE B 2 412 ? 78.855  102.545 76.568  1.00 221.72 ? 412 ILE B O   1 
ATOM   6320  C CB  . ILE B 2 412 ? 81.148  100.847 78.208  1.00 234.99 ? 412 ILE B CB  1 
ATOM   6321  C CG1 . ILE B 2 412 ? 82.305  99.874  77.975  1.00 262.65 ? 412 ILE B CG1 1 
ATOM   6322  C CG2 . ILE B 2 412 ? 79.846  100.069 78.339  1.00 237.62 ? 412 ILE B CG2 1 
ATOM   6323  C CD1 . ILE B 2 412 ? 82.368  99.315  76.566  1.00 253.02 ? 412 ILE B CD1 1 
ATOM   6324  N N   . ILE B 2 413 ? 80.000  104.030 77.818  1.00 245.06 ? 413 ILE B N   1 
ATOM   6325  C CA  . ILE B 2 413 ? 79.022  105.109 77.663  1.00 256.08 ? 413 ILE B CA  1 
ATOM   6326  C C   . ILE B 2 413 ? 78.835  105.412 76.172  1.00 218.09 ? 413 ILE B C   1 
ATOM   6327  O O   . ILE B 2 413 ? 77.701  105.462 75.680  1.00 251.27 ? 413 ILE B O   1 
ATOM   6328  C CB  . ILE B 2 413 ? 79.428  106.347 78.505  1.00 274.97 ? 413 ILE B CB  1 
ATOM   6329  C CG1 . ILE B 2 413 ? 79.194  106.065 79.995  1.00 306.75 ? 413 ILE B CG1 1 
ATOM   6330  C CG2 . ILE B 2 413 ? 78.733  107.639 78.067  1.00 291.37 ? 413 ILE B CG2 1 
ATOM   6331  C CD1 . ILE B 2 413 ? 79.835  107.060 80.936  1.00 325.55 ? 413 ILE B CD1 1 
ATOM   6332  N N   . GLY B 2 414 ? 79.965  105.612 75.480  1.00 211.20 ? 414 GLY B N   1 
ATOM   6333  C CA  . GLY B 2 414 ? 80.020  105.849 74.046  1.00 208.52 ? 414 GLY B CA  1 
ATOM   6334  C C   . GLY B 2 414 ? 79.242  104.812 73.241  1.00 223.98 ? 414 GLY B C   1 
ATOM   6335  O O   . GLY B 2 414 ? 78.499  105.192 72.333  1.00 350.17 ? 414 GLY B O   1 
ATOM   6336  N N   . MET B 2 415 ? 79.400  103.524 73.578  1.00 179.53 ? 415 MET B N   1 
ATOM   6337  C CA  . MET B 2 415 ? 78.732  102.454 72.850  1.00 218.38 ? 415 MET B CA  1 
ATOM   6338  C C   . MET B 2 415 ? 77.198  102.559 72.944  1.00 251.41 ? 415 MET B C   1 
ATOM   6339  O O   . MET B 2 415 ? 76.506  102.337 71.949  1.00 267.82 ? 415 MET B O   1 
ATOM   6340  C CB  . MET B 2 415 ? 79.192  101.090 73.368  1.00 255.80 ? 415 MET B CB  1 
ATOM   6341  C CG  . MET B 2 415 ? 78.723  99.939  72.494  1.00 300.30 ? 415 MET B CG  1 
ATOM   6342  S SD  . MET B 2 415 ? 79.191  98.337  73.168  1.00 305.59 ? 415 MET B SD  1 
ATOM   6343  C CE  . MET B 2 415 ? 77.911  98.157  74.408  1.00 280.48 ? 415 MET B CE  1 
ATOM   6344  N N   . ILE B 2 416 ? 76.661  102.896 74.124  1.00 269.94 ? 416 ILE B N   1 
ATOM   6345  C CA  . ILE B 2 416 ? 75.218  103.049 74.308  1.00 318.68 ? 416 ILE B CA  1 
ATOM   6346  C C   . ILE B 2 416 ? 74.705  104.324 73.618  1.00 305.60 ? 416 ILE B C   1 
ATOM   6347  O O   . ILE B 2 416 ? 73.674  104.279 72.938  1.00 301.42 ? 416 ILE B O   1 
ATOM   6348  C CB  . ILE B 2 416 ? 74.877  102.969 75.816  1.00 355.74 ? 416 ILE B CB  1 
ATOM   6349  C CG1 . ILE B 2 416 ? 75.268  101.600 76.396  1.00 376.59 ? 416 ILE B CG1 1 
ATOM   6350  C CG2 . ILE B 2 416 ? 73.417  103.309 76.100  1.00 379.46 ? 416 ILE B CG2 1 
ATOM   6351  C CD1 . ILE B 2 416 ? 74.759  100.395 75.621  1.00 361.01 ? 416 ILE B CD1 1 
ATOM   6352  N N   . TRP B 2 417 ? 75.417  105.448 73.777  1.00 287.06 ? 417 TRP B N   1 
ATOM   6353  C CA  . TRP B 2 417 ? 75.097  106.686 73.070  1.00 243.23 ? 417 TRP B CA  1 
ATOM   6354  C C   . TRP B 2 417 ? 75.107  106.473 71.547  1.00 225.07 ? 417 TRP B C   1 
ATOM   6355  O O   . TRP B 2 417 ? 74.242  107.014 70.860  1.00 264.06 ? 417 TRP B O   1 
ATOM   6356  C CB  . TRP B 2 417 ? 76.084  107.765 73.533  1.00 282.24 ? 417 TRP B CB  1 
ATOM   6357  C CG  . TRP B 2 417 ? 75.855  109.184 73.077  1.00 296.61 ? 417 TRP B CG  1 
ATOM   6358  C CD1 . TRP B 2 417 ? 75.317  110.183 73.839  1.00 276.39 ? 417 TRP B CD1 1 
ATOM   6359  C CD2 . TRP B 2 417 ? 76.181  109.784 71.796  1.00 351.77 ? 417 TRP B CD2 1 
ATOM   6360  N NE1 . TRP B 2 417 ? 75.267  111.353 73.127  1.00 303.08 ? 417 TRP B NE1 1 
ATOM   6361  C CE2 . TRP B 2 417 ? 75.790  111.147 71.873  1.00 373.48 ? 417 TRP B CE2 1 
ATOM   6362  C CE3 . TRP B 2 417 ? 76.752  109.320 70.595  1.00 356.67 ? 417 TRP B CE3 1 
ATOM   6363  C CZ2 . TRP B 2 417 ? 75.958  112.031 70.799  1.00 402.43 ? 417 TRP B CZ2 1 
ATOM   6364  C CZ3 . TRP B 2 417 ? 76.917  110.197 69.537  1.00 397.69 ? 417 TRP B CZ3 1 
ATOM   6365  C CH2 . TRP B 2 417 ? 76.523  111.536 69.640  1.00 401.45 ? 417 TRP B CH2 1 
ATOM   6366  N N   . LEU B 2 418 ? 76.051  105.662 71.022  1.00 243.64 ? 418 LEU B N   1 
ATOM   6367  C CA  . LEU B 2 418 ? 76.100  105.298 69.602  1.00 283.08 ? 418 LEU B CA  1 
ATOM   6368  C C   . LEU B 2 418 ? 74.944  104.365 69.194  1.00 346.74 ? 418 LEU B C   1 
ATOM   6369  O O   . LEU B 2 418 ? 74.394  104.565 68.108  1.00 439.05 ? 418 LEU B O   1 
ATOM   6370  C CB  . LEU B 2 418 ? 77.466  104.674 69.280  1.00 319.89 ? 418 LEU B CB  1 
ATOM   6371  C CG  . LEU B 2 418 ? 77.699  104.201 67.843  1.00 344.78 ? 418 LEU B CG  1 
ATOM   6372  C CD1 . LEU B 2 418 ? 77.624  105.362 66.862  1.00 366.82 ? 418 LEU B CD1 1 
ATOM   6373  C CD2 . LEU B 2 418 ? 79.045  103.496 67.724  1.00 365.70 ? 418 LEU B CD2 1 
ATOM   6374  N N   . ARG B 2 419 ? 74.566  103.370 70.023  1.00 312.42 ? 419 ARG B N   1 
ATOM   6375  C CA  . ARG B 2 419 ? 73.412  102.505 69.751  1.00 315.50 ? 419 ARG B CA  1 
ATOM   6376  C C   . ARG B 2 419 ? 72.103  103.311 69.670  1.00 320.83 ? 419 ARG B C   1 
ATOM   6377  O O   . ARG B 2 419 ? 71.226  102.974 68.869  1.00 265.79 ? 419 ARG B O   1 
ATOM   6378  C CB  . ARG B 2 419 ? 73.316  101.380 70.792  1.00 321.04 ? 419 ARG B CB  1 
ATOM   6379  C CG  . ARG B 2 419 ? 72.305  100.302 70.428  1.00 334.20 ? 419 ARG B CG  1 
ATOM   6380  C CD  . ARG B 2 419 ? 72.182  99.186  71.447  1.00 343.89 ? 419 ARG B CD  1 
ATOM   6381  N NE  . ARG B 2 419 ? 73.279  98.226  71.402  1.00 326.03 ? 419 ARG B NE  1 
ATOM   6382  C CZ  . ARG B 2 419 ? 73.272  97.015  71.966  1.00 319.28 ? 419 ARG B CZ  1 
ATOM   6383  N NH1 . ARG B 2 419 ? 74.369  96.281  71.935  1.00 343.76 ? 419 ARG B NH1 1 
ATOM   6384  N NH2 . ARG B 2 419 ? 72.197  96.529  72.573  1.00 294.44 ? 419 ARG B NH2 1 
ATOM   6385  N N   . HIS B 2 420 ? 71.983  104.370 70.489  1.00 343.90 ? 420 HIS B N   1 
ATOM   6386  C CA  . HIS B 2 420 ? 70.894  105.347 70.417  1.00 339.61 ? 420 HIS B CA  1 
ATOM   6387  C C   . HIS B 2 420 ? 70.967  106.215 69.146  1.00 331.74 ? 420 HIS B C   1 
ATOM   6388  O O   . HIS B 2 420 ? 69.980  106.310 68.414  1.00 222.08 ? 420 HIS B O   1 
ATOM   6389  C CB  . HIS B 2 420 ? 70.907  106.165 71.715  1.00 346.92 ? 420 HIS B CB  1 
ATOM   6390  C CG  . HIS B 2 420 ? 69.913  107.269 71.850  1.00 350.64 ? 420 HIS B CG  1 
ATOM   6391  N ND1 . HIS B 2 420 ? 69.890  108.449 71.137  1.00 358.02 ? 420 HIS B ND1 1 
ATOM   6392  C CD2 . HIS B 2 420 ? 68.884  107.332 72.710  1.00 297.56 ? 420 HIS B CD2 1 
ATOM   6393  C CE1 . HIS B 2 420 ? 68.863  109.186 71.555  1.00 343.78 ? 420 HIS B CE1 1 
ATOM   6394  N NE2 . HIS B 2 420 ? 68.236  108.528 72.514  1.00 279.95 ? 420 HIS B NE2 1 
ATOM   6395  N N   . ARG B 2 421 ? 72.126  106.854 68.892  1.00 376.24 ? 421 ARG B N   1 
ATOM   6396  C CA  . ARG B 2 421 ? 72.298  107.881 67.861  1.00 337.93 ? 421 ARG B CA  1 
ATOM   6397  C C   . ARG B 2 421 ? 72.301  107.312 66.430  1.00 333.14 ? 421 ARG B C   1 
ATOM   6398  O O   . ARG B 2 421 ? 71.789  107.977 65.528  1.00 312.70 ? 421 ARG B O   1 
ATOM   6399  C CB  . ARG B 2 421 ? 73.609  108.645 68.119  1.00 362.86 ? 421 ARG B CB  1 
ATOM   6400  C CG  . ARG B 2 421 ? 73.780  109.946 67.343  1.00 356.50 ? 421 ARG B CG  1 
ATOM   6401  C CD  . ARG B 2 421 ? 72.837  111.050 67.792  1.00 386.85 ? 421 ARG B CD  1 
ATOM   6402  N NE  . ARG B 2 421 ? 73.050  111.450 69.183  1.00 416.28 ? 421 ARG B NE  1 
ATOM   6403  C CZ  . ARG B 2 421 ? 72.319  112.345 69.857  1.00 377.02 ? 421 ARG B CZ  1 
ATOM   6404  N NH1 . ARG B 2 421 ? 72.620  112.625 71.115  1.00 367.15 ? 421 ARG B NH1 1 
ATOM   6405  N NH2 . ARG B 2 421 ? 71.292  112.961 69.291  1.00 314.59 ? 421 ARG B NH2 1 
ATOM   6406  N N   . LYS B 2 422 ? 72.883  106.113 66.216  1.00 353.34 ? 422 LYS B N   1 
ATOM   6407  C CA  . LYS B 2 422 ? 72.971  105.463 64.909  1.00 335.03 ? 422 LYS B CA  1 
ATOM   6408  C C   . LYS B 2 422 ? 72.508  104.009 65.028  1.00 356.83 ? 422 LYS B C   1 
ATOM   6409  O O   . LYS B 2 422 ? 73.338  103.097 65.075  1.00 349.45 ? 422 LYS B O   1 
ATOM   6410  C CB  . LYS B 2 422 ? 74.399  105.531 64.356  1.00 330.48 ? 422 LYS B CB  1 
ATOM   6411  C CG  . LYS B 2 422 ? 74.872  106.924 63.969  1.00 341.39 ? 422 LYS B CG  1 
ATOM   6412  C CD  . LYS B 2 422 ? 76.108  106.882 63.072  1.00 328.74 ? 422 LYS B CD  1 
ATOM   6413  C CE  . LYS B 2 422 ? 76.655  108.244 62.690  1.00 305.99 ? 422 LYS B CE  1 
ATOM   6414  N NZ  . LYS B 2 422 ? 77.406  108.887 63.799  1.00 292.42 ? 422 LYS B NZ  1 
ATOM   6415  N N   . PRO B 2 423 ? 71.178  103.748 65.076  1.00 396.05 ? 423 PRO B N   1 
ATOM   6416  C CA  . PRO B 2 423 ? 70.667  102.391 65.272  1.00 419.71 ? 423 PRO B CA  1 
ATOM   6417  C C   . PRO B 2 423 ? 70.935  101.483 64.067  1.00 424.05 ? 423 PRO B C   1 
ATOM   6418  O O   . PRO B 2 423 ? 71.017  101.949 62.927  1.00 364.40 ? 423 PRO B O   1 
ATOM   6419  C CB  . PRO B 2 423 ? 69.159  102.598 65.516  1.00 439.43 ? 423 PRO B CB  1 
ATOM   6420  C CG  . PRO B 2 423 ? 68.838  103.903 64.827  1.00 444.30 ? 423 PRO B CG  1 
ATOM   6421  C CD  . PRO B 2 423 ? 70.095  104.736 64.945  1.00 410.99 ? 423 PRO B CD  1 
ATOM   6422  N N   . GLU B 2 424 ? 71.087  100.182 64.369  1.00 460.23 ? 424 GLU B N   1 
ATOM   6423  C CA  . GLU B 2 424 ? 71.208  99.078  63.416  1.00 476.45 ? 424 GLU B CA  1 
ATOM   6424  C C   . GLU B 2 424 ? 72.375  99.299  62.438  1.00 428.57 ? 424 GLU B C   1 
ATOM   6425  O O   . GLU B 2 424 ? 72.270  99.020  61.237  1.00 416.70 ? 424 GLU B O   1 
ATOM   6426  C CB  . GLU B 2 424 ? 69.851  98.839  62.731  1.00 522.09 ? 424 GLU B CB  1 
ATOM   6427  C CG  . GLU B 2 424 ? 69.642  97.440  62.163  1.00 544.48 ? 424 GLU B CG  1 
ATOM   6428  C CD  . GLU B 2 424 ? 69.646  96.308  63.178  1.00 543.95 ? 424 GLU B CD  1 
ATOM   6429  O OE1 . GLU B 2 424 ? 70.746  95.899  63.589  1.00 554.99 ? 424 GLU B OE1 1 
ATOM   6430  O OE2 . GLU B 2 424 ? 68.554  95.840  63.558  1.00 519.99 ? 424 GLU B OE2 1 
ATOM   6431  N N   . LEU B 2 425 ? 73.520  99.771  62.964  1.00 394.14 ? 425 LEU B N   1 
ATOM   6432  C CA  . LEU B 2 425 ? 74.732  99.994  62.173  1.00 376.17 ? 425 LEU B CA  1 
ATOM   6433  C C   . LEU B 2 425 ? 75.501  98.674  61.950  1.00 394.72 ? 425 LEU B C   1 
ATOM   6434  O O   . LEU B 2 425 ? 76.675  98.556  62.316  1.00 304.09 ? 425 LEU B O   1 
ATOM   6435  C CB  . LEU B 2 425 ? 75.563  101.070 62.894  1.00 360.99 ? 425 LEU B CB  1 
ATOM   6436  C CG  . LEU B 2 425 ? 76.787  101.644 62.172  1.00 377.06 ? 425 LEU B CG  1 
ATOM   6437  C CD1 . LEU B 2 425 ? 76.515  101.947 60.704  1.00 361.66 ? 425 LEU B CD1 1 
ATOM   6438  C CD2 . LEU B 2 425 ? 77.255  102.912 62.879  1.00 391.81 ? 425 LEU B CD2 1 
ATOM   6439  N N   . GLU B 2 426 ? 74.815  97.689  61.329  1.00 439.96 ? 426 GLU B N   1 
ATOM   6440  C CA  . GLU B 2 426 ? 75.356  96.440  60.783  1.00 433.76 ? 426 GLU B CA  1 
ATOM   6441  C C   . GLU B 2 426 ? 76.172  95.612  61.795  1.00 350.56 ? 426 GLU B C   1 
ATOM   6442  O O   . GLU B 2 426 ? 77.153  94.976  61.405  1.00 354.65 ? 426 GLU B O   1 
ATOM   6443  C CB  . GLU B 2 426 ? 76.170  96.745  59.513  1.00 487.39 ? 426 GLU B CB  1 
ATOM   6444  C CG  . GLU B 2 426 ? 75.358  97.405  58.400  1.00 554.17 ? 426 GLU B CG  1 
ATOM   6445  C CD  . GLU B 2 426 ? 76.051  97.506  57.047  1.00 597.29 ? 426 GLU B CD  1 
ATOM   6446  O OE1 . GLU B 2 426 ? 76.554  96.470  56.566  1.00 596.27 ? 426 GLU B OE1 1 
ATOM   6447  O OE2 . GLU B 2 426 ? 76.082  98.618  56.470  1.00 646.26 ? 426 GLU B OE2 1 
ATOM   6448  N N   . ARG B 2 427 ? 75.753  95.582  63.073  1.00 295.50 ? 427 ARG B N   1 
ATOM   6449  C CA  . ARG B 2 427 ? 76.543  95.030  64.178  1.00 250.21 ? 427 ARG B CA  1 
ATOM   6450  C C   . ARG B 2 427 ? 76.676  93.503  64.081  1.00 244.72 ? 427 ARG B C   1 
ATOM   6451  O O   . ARG B 2 427 ? 75.667  92.812  64.184  1.00 265.49 ? 427 ARG B O   1 
ATOM   6452  C CB  . ARG B 2 427 ? 75.903  95.363  65.528  1.00 215.74 ? 427 ARG B CB  1 
ATOM   6453  C CG  . ARG B 2 427 ? 75.705  96.850  65.771  1.00 260.75 ? 427 ARG B CG  1 
ATOM   6454  C CD  . ARG B 2 427 ? 75.126  97.180  67.136  1.00 260.52 ? 427 ARG B CD  1 
ATOM   6455  N NE  . ARG B 2 427 ? 74.935  98.627  67.245  1.00 279.21 ? 427 ARG B NE  1 
ATOM   6456  C CZ  . ARG B 2 427 ? 75.690  99.482  67.944  1.00 326.35 ? 427 ARG B CZ  1 
ATOM   6457  N NH1 . ARG B 2 427 ? 75.631  100.776 67.672  1.00 294.74 ? 427 ARG B NH1 1 
ATOM   6458  N NH2 . ARG B 2 427 ? 76.525  99.066  68.886  1.00 385.05 ? 427 ARG B NH2 1 
ATOM   6459  N N   . PRO B 2 428 ? 77.884  92.900  63.876  1.00 286.77 ? 428 PRO B N   1 
ATOM   6460  C CA  . PRO B 2 428 ? 78.032  91.437  63.892  1.00 290.06 ? 428 PRO B CA  1 
ATOM   6461  C C   . PRO B 2 428 ? 77.773  90.801  65.265  1.00 310.66 ? 428 PRO B C   1 
ATOM   6462  O O   . PRO B 2 428 ? 77.388  89.634  65.321  1.00 294.52 ? 428 PRO B O   1 
ATOM   6463  C CB  . PRO B 2 428 ? 79.487  91.186  63.445  1.00 274.86 ? 428 PRO B CB  1 
ATOM   6464  C CG  . PRO B 2 428 ? 79.970  92.508  62.868  1.00 302.67 ? 428 PRO B CG  1 
ATOM   6465  C CD  . PRO B 2 428 ? 79.173  93.565  63.607  1.00 334.78 ? 428 PRO B CD  1 
ATOM   6466  N N   . ILE B 2 429 ? 77.994  91.575  66.344  1.00 300.01 ? 429 ILE B N   1 
ATOM   6467  C CA  . ILE B 2 429 ? 77.658  91.207  67.713  1.00 295.91 ? 429 ILE B CA  1 
ATOM   6468  C C   . ILE B 2 429 ? 76.833  92.344  68.325  1.00 293.43 ? 429 ILE B C   1 
ATOM   6469  O O   . ILE B 2 429 ? 77.187  93.507  68.165  1.00 242.83 ? 429 ILE B O   1 
ATOM   6470  C CB  . ILE B 2 429 ? 78.939  90.930  68.529  1.00 306.29 ? 429 ILE B CB  1 
ATOM   6471  C CG1 . ILE B 2 429 ? 79.786  89.826  67.893  1.00 277.82 ? 429 ILE B CG1 1 
ATOM   6472  C CG2 . ILE B 2 429 ? 78.590  90.603  69.982  1.00 330.41 ? 429 ILE B CG2 1 
ATOM   6473  C CD1 . ILE B 2 429 ? 81.147  89.664  68.521  1.00 318.82 ? 429 ILE B CD1 1 
ATOM   6474  N N   . LYS B 2 430 ? 75.742  91.997  69.032  1.00 328.76 ? 430 LYS B N   1 
ATOM   6475  C CA  . LYS B 2 430 ? 74.880  92.959  69.708  1.00 338.55 ? 430 LYS B CA  1 
ATOM   6476  C C   . LYS B 2 430 ? 74.453  92.385  71.066  1.00 354.17 ? 430 LYS B C   1 
ATOM   6477  O O   . LYS B 2 430 ? 73.527  91.577  71.151  1.00 402.39 ? 430 LYS B O   1 
ATOM   6478  C CB  . LYS B 2 430 ? 73.703  93.344  68.800  1.00 371.34 ? 430 LYS B CB  1 
ATOM   6479  C CG  . LYS B 2 430 ? 73.032  92.205  68.034  1.00 401.21 ? 430 LYS B CG  1 
ATOM   6480  C CD  . LYS B 2 430 ? 71.769  92.602  67.296  1.00 402.61 ? 430 LYS B CD  1 
ATOM   6481  C CE  . LYS B 2 430 ? 72.021  93.535  66.131  1.00 406.73 ? 430 LYS B CE  1 
ATOM   6482  N NZ  . LYS B 2 430 ? 70.780  93.812  65.367  1.00 428.87 ? 430 LYS B NZ  1 
ATOM   6483  N N   . VAL B 2 431 ? 75.139  92.820  72.136  1.00 335.72 ? 431 VAL B N   1 
ATOM   6484  C CA  . VAL B 2 431 ? 74.889  92.325  73.489  1.00 327.12 ? 431 VAL B CA  1 
ATOM   6485  C C   . VAL B 2 431 ? 73.602  92.943  74.049  1.00 316.15 ? 431 VAL B C   1 
ATOM   6486  O O   . VAL B 2 431 ? 73.195  94.041  73.661  1.00 332.19 ? 431 VAL B O   1 
ATOM   6487  C CB  . VAL B 2 431 ? 76.082  92.572  74.446  1.00 358.50 ? 431 VAL B CB  1 
ATOM   6488  C CG1 . VAL B 2 431 ? 77.379  92.003  73.888  1.00 374.11 ? 431 VAL B CG1 1 
ATOM   6489  C CG2 . VAL B 2 431 ? 76.270  94.043  74.821  1.00 380.29 ? 431 VAL B CG2 1 
ATOM   6490  N N   . ASN B 2 432 ? 72.973  92.214  74.983  1.00 299.83 ? 432 ASN B N   1 
ATOM   6491  C CA  . ASN B 2 432 ? 71.827  92.685  75.753  1.00 322.05 ? 432 ASN B CA  1 
ATOM   6492  C C   . ASN B 2 432 ? 72.179  93.983  76.495  1.00 291.02 ? 432 ASN B C   1 
ATOM   6493  O O   . ASN B 2 432 ? 73.195  94.025  77.185  1.00 278.57 ? 432 ASN B O   1 
ATOM   6494  C CB  . ASN B 2 432 ? 71.375  91.557  76.691  1.00 340.91 ? 432 ASN B CB  1 
ATOM   6495  C CG  . ASN B 2 432 ? 70.168  91.846  77.565  1.00 343.26 ? 432 ASN B CG  1 
ATOM   6496  O OD1 . ASN B 2 432 ? 69.657  92.964  77.609  1.00 401.37 ? 432 ASN B OD1 1 
ATOM   6497  N ND2 . ASN B 2 432 ? 69.701  90.828  78.277  1.00 270.45 ? 432 ASN B ND2 1 
ATOM   6498  N N   . LEU B 2 433 ? 71.327  95.024  76.367  1.00 270.88 ? 433 LEU B N   1 
ATOM   6499  C CA  . LEU B 2 433 ? 71.517  96.315  77.031  1.00 296.73 ? 433 LEU B CA  1 
ATOM   6500  C C   . LEU B 2 433 ? 71.688  96.173  78.555  1.00 302.68 ? 433 LEU B C   1 
ATOM   6501  O O   . LEU B 2 433 ? 72.357  97.008  79.172  1.00 273.42 ? 433 LEU B O   1 
ATOM   6502  C CB  . LEU B 2 433 ? 70.325  97.218  76.671  1.00 333.22 ? 433 LEU B CB  1 
ATOM   6503  C CG  . LEU B 2 433 ? 70.312  98.627  77.272  1.00 370.45 ? 433 LEU B CG  1 
ATOM   6504  C CD1 . LEU B 2 433 ? 71.533  99.426  76.842  1.00 385.49 ? 433 LEU B CD1 1 
ATOM   6505  C CD2 . LEU B 2 433 ? 69.043  99.373  76.882  1.00 363.38 ? 433 LEU B CD2 1 
ATOM   6506  N N   . ALA B 2 434 ? 71.098  95.118  79.156  1.00 386.26 ? 434 ALA B N   1 
ATOM   6507  C CA  . ALA B 2 434 ? 71.198  94.802  80.580  1.00 451.92 ? 434 ALA B CA  1 
ATOM   6508  C C   . ALA B 2 434 ? 72.638  94.633  81.099  1.00 456.48 ? 434 ALA B C   1 
ATOM   6509  O O   . ALA B 2 434 ? 72.845  94.762  82.309  1.00 499.12 ? 434 ALA B O   1 
ATOM   6510  C CB  . ALA B 2 434 ? 70.378  93.559  80.859  1.00 468.16 ? 434 ALA B CB  1 
ATOM   6511  N N   . LEU B 2 435 ? 73.626  94.349  80.227  1.00 376.49 ? 435 LEU B N   1 
ATOM   6512  C CA  . LEU B 2 435 ? 75.016  94.221  80.656  1.00 294.11 ? 435 LEU B CA  1 
ATOM   6513  C C   . LEU B 2 435 ? 75.670  95.611  80.778  1.00 236.07 ? 435 LEU B C   1 
ATOM   6514  O O   . LEU B 2 435 ? 76.020  95.997  81.897  1.00 247.61 ? 435 LEU B O   1 
ATOM   6515  C CB  . LEU B 2 435 ? 75.718  93.205  79.731  1.00 266.96 ? 435 LEU B CB  1 
ATOM   6516  C CG  . LEU B 2 435 ? 75.350  91.752  80.057  1.00 277.40 ? 435 LEU B CG  1 
ATOM   6517  C CD1 . LEU B 2 435 ? 75.489  90.850  78.842  1.00 251.32 ? 435 LEU B CD1 1 
ATOM   6518  C CD2 . LEU B 2 435 ? 76.190  91.201  81.209  1.00 301.21 ? 435 LEU B CD2 1 
ATOM   6519  N N   . PRO B 2 436 ? 75.875  96.417  79.706  1.00 215.54 ? 436 PRO B N   1 
ATOM   6520  C CA  . PRO B 2 436 ? 76.340  97.803  79.860  1.00 237.95 ? 436 PRO B CA  1 
ATOM   6521  C C   . PRO B 2 436 ? 75.653  98.675  80.919  1.00 240.80 ? 436 PRO B C   1 
ATOM   6522  O O   . PRO B 2 436 ? 76.358  99.435  81.568  1.00 262.73 ? 436 PRO B O   1 
ATOM   6523  C CB  . PRO B 2 436 ? 76.140  98.411  78.459  1.00 262.99 ? 436 PRO B CB  1 
ATOM   6524  C CG  . PRO B 2 436 ? 76.324  97.226  77.538  1.00 254.73 ? 436 PRO B CG  1 
ATOM   6525  C CD  . PRO B 2 436 ? 75.729  96.054  78.288  1.00 220.10 ? 436 PRO B CD  1 
ATOM   6526  N N   . VAL B 2 437 ? 74.332  98.581  81.140  1.00 276.50 ? 437 VAL B N   1 
ATOM   6527  C CA  . VAL B 2 437 ? 73.683  99.456  82.127  1.00 347.17 ? 437 VAL B CA  1 
ATOM   6528  C C   . VAL B 2 437 ? 74.036  99.087  83.581  1.00 387.75 ? 437 VAL B C   1 
ATOM   6529  O O   . VAL B 2 437 ? 73.825  99.909  84.474  1.00 415.58 ? 437 VAL B O   1 
ATOM   6530  C CB  . VAL B 2 437 ? 72.149  99.548  81.949  1.00 409.51 ? 437 VAL B CB  1 
ATOM   6531  C CG1 . VAL B 2 437 ? 71.781  100.124 80.588  1.00 399.05 ? 437 VAL B CG1 1 
ATOM   6532  C CG2 . VAL B 2 437 ? 71.426  98.229  82.204  1.00 424.74 ? 437 VAL B CG2 1 
ATOM   6533  N N   . PHE B 2 438 ? 74.552  97.874  83.843  1.00 413.27 ? 438 PHE B N   1 
ATOM   6534  C CA  . PHE B 2 438 ? 75.208  97.562  85.111  1.00 409.49 ? 438 PHE B CA  1 
ATOM   6535  C C   . PHE B 2 438 ? 76.677  97.992  85.076  1.00 352.94 ? 438 PHE B C   1 
ATOM   6536  O O   . PHE B 2 438 ? 77.162  98.603  86.033  1.00 327.19 ? 438 PHE B O   1 
ATOM   6537  C CB  . PHE B 2 438 ? 75.077  96.069  85.442  1.00 446.51 ? 438 PHE B CB  1 
ATOM   6538  C CG  . PHE B 2 438 ? 73.709  95.549  85.837  1.00 529.64 ? 438 PHE B CG  1 
ATOM   6539  C CD1 . PHE B 2 438 ? 72.589  96.376  85.971  1.00 576.21 ? 438 PHE B CD1 1 
ATOM   6540  C CD2 . PHE B 2 438 ? 73.545  94.188  86.084  1.00 529.39 ? 438 PHE B CD2 1 
ATOM   6541  C CE1 . PHE B 2 438 ? 71.355  95.850  86.337  1.00 568.24 ? 438 PHE B CE1 1 
ATOM   6542  C CE2 . PHE B 2 438 ? 72.309  93.667  86.450  1.00 535.11 ? 438 PHE B CE2 1 
ATOM   6543  C CZ  . PHE B 2 438 ? 71.216  94.498  86.576  1.00 549.88 ? 438 PHE B CZ  1 
ATOM   6544  N N   . PHE B 2 439 ? 77.371  97.675  83.973  1.00 340.23 ? 439 PHE B N   1 
ATOM   6545  C CA  . PHE B 2 439 ? 78.809  97.874  83.842  1.00 334.21 ? 439 PHE B CA  1 
ATOM   6546  C C   . PHE B 2 439 ? 79.220  99.360  83.898  1.00 310.04 ? 439 PHE B C   1 
ATOM   6547  O O   . PHE B 2 439 ? 80.186  99.690  84.586  1.00 239.36 ? 439 PHE B O   1 
ATOM   6548  C CB  . PHE B 2 439 ? 79.282  97.193  82.553  1.00 328.42 ? 439 PHE B CB  1 
ATOM   6549  C CG  . PHE B 2 439 ? 80.777  97.182  82.384  1.00 311.80 ? 439 PHE B CG  1 
ATOM   6550  C CD1 . PHE B 2 439 ? 81.553  96.201  82.984  1.00 254.39 ? 439 PHE B CD1 1 
ATOM   6551  C CD2 . PHE B 2 439 ? 81.406  98.171  81.640  1.00 344.83 ? 439 PHE B CD2 1 
ATOM   6552  C CE1 . PHE B 2 439 ? 82.931  96.210  82.835  1.00 286.05 ? 439 PHE B CE1 1 
ATOM   6553  C CE2 . PHE B 2 439 ? 82.786  98.175  81.487  1.00 329.66 ? 439 PHE B CE2 1 
ATOM   6554  C CZ  . PHE B 2 439 ? 83.549  97.197  82.090  1.00 306.29 ? 439 PHE B CZ  1 
ATOM   6555  N N   . ILE B 2 440 ? 78.514  100.259 83.185  1.00 296.84 ? 440 ILE B N   1 
ATOM   6556  C CA  . ILE B 2 440 ? 78.773  101.697 83.240  1.00 299.89 ? 440 ILE B CA  1 
ATOM   6557  C C   . ILE B 2 440 ? 78.679  102.182 84.690  1.00 299.60 ? 440 ILE B C   1 
ATOM   6558  O O   . ILE B 2 440 ? 79.530  102.943 85.148  1.00 259.46 ? 440 ILE B O   1 
ATOM   6559  C CB  . ILE B 2 440 ? 77.814  102.487 82.315  1.00 356.94 ? 440 ILE B CB  1 
ATOM   6560  C CG1 . ILE B 2 440 ? 78.093  102.219 80.834  1.00 334.25 ? 440 ILE B CG1 1 
ATOM   6561  C CG2 . ILE B 2 440 ? 77.846  103.992 82.596  1.00 413.79 ? 440 ILE B CG2 1 
ATOM   6562  C CD1 . ILE B 2 440 ? 76.972  102.644 79.908  1.00 334.42 ? 440 ILE B CD1 1 
ATOM   6563  N N   . LEU B 2 441 ? 77.634  101.748 85.408  1.00 330.34 ? 441 LEU B N   1 
ATOM   6564  C CA  . LEU B 2 441 ? 77.447  102.119 86.806  1.00 380.81 ? 441 LEU B CA  1 
ATOM   6565  C C   . LEU B 2 441 ? 78.565  101.547 87.690  1.00 343.39 ? 441 LEU B C   1 
ATOM   6566  O O   . LEU B 2 441 ? 78.951  102.191 88.664  1.00 329.28 ? 441 LEU B O   1 
ATOM   6567  C CB  . LEU B 2 441 ? 76.046  101.689 87.264  1.00 462.55 ? 441 LEU B CB  1 
ATOM   6568  C CG  . LEU B 2 441 ? 74.937  102.722 87.044  1.00 498.00 ? 441 LEU B CG  1 
ATOM   6569  C CD1 . LEU B 2 441 ? 74.801  103.137 85.582  1.00 469.42 ? 441 LEU B CD1 1 
ATOM   6570  C CD2 . LEU B 2 441 ? 73.611  102.186 87.556  1.00 537.90 ? 441 LEU B CD2 1 
ATOM   6571  N N   . ALA B 2 442 ? 79.098  100.363 87.358  1.00 330.08 ? 442 ALA B N   1 
ATOM   6572  C CA  . ALA B 2 442 ? 80.233  99.791  88.075  1.00 336.00 ? 442 ALA B CA  1 
ATOM   6573  C C   . ALA B 2 442 ? 81.515  100.608 87.852  1.00 302.64 ? 442 ALA B C   1 
ATOM   6574  O O   . ALA B 2 442 ? 82.257  100.842 88.810  1.00 288.79 ? 442 ALA B O   1 
ATOM   6575  C CB  . ALA B 2 442 ? 80.382  98.337  87.687  1.00 365.71 ? 442 ALA B CB  1 
ATOM   6576  N N   . CYS B 2 443 ? 81.787  101.059 86.615  1.00 325.62 ? 443 CYS B N   1 
ATOM   6577  C CA  . CYS B 2 443 ? 82.882  101.992 86.355  1.00 351.49 ? 443 CYS B CA  1 
ATOM   6578  C C   . CYS B 2 443 ? 82.707  103.290 87.160  1.00 294.72 ? 443 CYS B C   1 
ATOM   6579  O O   . CYS B 2 443 ? 83.648  103.776 87.794  1.00 191.51 ? 443 CYS B O   1 
ATOM   6580  C CB  . CYS B 2 443 ? 82.996  102.322 84.867  1.00 361.26 ? 443 CYS B CB  1 
ATOM   6581  S SG  . CYS B 2 443 ? 83.356  100.899 83.802  1.00 307.02 ? 443 CYS B SG  1 
ATOM   6582  N N   . LEU B 2 444 ? 81.495  103.855 87.142  1.00 291.24 ? 444 LEU B N   1 
ATOM   6583  C CA  . LEU B 2 444 ? 81.205  105.075 87.882  1.00 318.89 ? 444 LEU B CA  1 
ATOM   6584  C C   . LEU B 2 444 ? 81.365  104.849 89.390  1.00 267.41 ? 444 LEU B C   1 
ATOM   6585  O O   . LEU B 2 444 ? 81.873  105.735 90.069  1.00 266.67 ? 444 LEU B O   1 
ATOM   6586  C CB  . LEU B 2 444 ? 79.798  105.565 87.508  1.00 360.61 ? 444 LEU B CB  1 
ATOM   6587  C CG  . LEU B 2 444 ? 79.656  106.119 86.089  1.00 388.57 ? 444 LEU B CG  1 
ATOM   6588  C CD1 . LEU B 2 444 ? 78.191  106.282 85.712  1.00 418.97 ? 444 LEU B CD1 1 
ATOM   6589  C CD2 . LEU B 2 444 ? 80.390  107.448 85.940  1.00 381.61 ? 444 LEU B CD2 1 
ATOM   6590  N N   . PHE B 2 445 ? 80.953  103.682 89.910  1.00 229.20 ? 445 PHE B N   1 
ATOM   6591  C CA  . PHE B 2 445 ? 81.068  103.362 91.329  1.00 279.54 ? 445 PHE B CA  1 
ATOM   6592  C C   . PHE B 2 445 ? 82.530  103.444 91.786  1.00 257.69 ? 445 PHE B C   1 
ATOM   6593  O O   . PHE B 2 445 ? 82.835  104.123 92.767  1.00 203.74 ? 445 PHE B O   1 
ATOM   6594  C CB  . PHE B 2 445 ? 80.418  101.997 91.594  1.00 332.96 ? 445 PHE B CB  1 
ATOM   6595  C CG  . PHE B 2 445 ? 80.749  101.345 92.915  1.00 391.49 ? 445 PHE B CG  1 
ATOM   6596  C CD1 . PHE B 2 445 ? 80.485  101.990 94.119  1.00 388.28 ? 445 PHE B CD1 1 
ATOM   6597  C CD2 . PHE B 2 445 ? 81.325  100.076 92.959  1.00 392.97 ? 445 PHE B CD2 1 
ATOM   6598  C CE1 . PHE B 2 445 ? 80.792  101.384 95.331  1.00 361.72 ? 445 PHE B CE1 1 
ATOM   6599  C CE2 . PHE B 2 445 ? 81.628  99.471  94.173  1.00 326.61 ? 445 PHE B CE2 1 
ATOM   6600  C CZ  . PHE B 2 445 ? 81.362  100.126 95.356  1.00 341.10 ? 445 PHE B CZ  1 
ATOM   6601  N N   . LEU B 2 446 ? 83.426  102.753 91.069  1.00 266.42 ? 446 LEU B N   1 
ATOM   6602  C CA  . LEU B 2 446 ? 84.856  102.756 91.370  1.00 250.59 ? 446 LEU B CA  1 
ATOM   6603  C C   . LEU B 2 446 ? 85.427  104.177 91.364  1.00 218.50 ? 446 LEU B C   1 
ATOM   6604  O O   . LEU B 2 446 ? 86.110  104.549 92.314  1.00 197.31 ? 446 LEU B O   1 
ATOM   6605  C CB  . LEU B 2 446 ? 85.587  101.839 90.372  1.00 272.97 ? 446 LEU B CB  1 
ATOM   6606  C CG  . LEU B 2 446 ? 85.889  100.415 90.854  1.00 262.18 ? 446 LEU B CG  1 
ATOM   6607  C CD1 . LEU B 2 446 ? 84.661  99.680  91.391  1.00 261.53 ? 446 LEU B CD1 1 
ATOM   6608  C CD2 . LEU B 2 446 ? 86.512  99.602  89.727  1.00 253.33 ? 446 LEU B CD2 1 
ATOM   6609  N N   . ILE B 2 447 ? 85.145  104.955 90.308  1.00 250.88 ? 447 ILE B N   1 
ATOM   6610  C CA  . ILE B 2 447 ? 85.627  106.331 90.177  1.00 298.56 ? 447 ILE B CA  1 
ATOM   6611  C C   . ILE B 2 447 ? 85.078  107.208 91.319  1.00 295.01 ? 447 ILE B C   1 
ATOM   6612  O O   . ILE B 2 447 ? 85.847  107.909 91.986  1.00 200.09 ? 447 ILE B O   1 
ATOM   6613  C CB  . ILE B 2 447 ? 85.324  106.877 88.752  1.00 275.14 ? 447 ILE B CB  1 
ATOM   6614  C CG1 . ILE B 2 447 ? 86.440  106.534 87.761  1.00 262.37 ? 447 ILE B CG1 1 
ATOM   6615  C CG2 . ILE B 2 447 ? 85.085  108.388 88.714  1.00 320.01 ? 447 ILE B CG2 1 
ATOM   6616  C CD1 . ILE B 2 447 ? 86.906  105.091 87.756  1.00 305.61 ? 447 ILE B CD1 1 
ATOM   6617  N N   . ALA B 2 448 ? 83.755  107.159 91.543  1.00 304.03 ? 448 ALA B N   1 
ATOM   6618  C CA  . ALA B 2 448 ? 83.070  108.052 92.468  1.00 300.13 ? 448 ALA B CA  1 
ATOM   6619  C C   . ALA B 2 448 ? 83.572  107.877 93.905  1.00 291.09 ? 448 ALA B C   1 
ATOM   6620  O O   . ALA B 2 448 ? 83.725  108.876 94.608  1.00 339.38 ? 448 ALA B O   1 
ATOM   6621  C CB  . ALA B 2 448 ? 81.573  107.844 92.366  1.00 341.72 ? 448 ALA B CB  1 
ATOM   6622  N N   . VAL B 2 449 ? 83.825  106.630 94.341  1.00 303.58 ? 449 VAL B N   1 
ATOM   6623  C CA  . VAL B 2 449 ? 84.430  106.366 95.645  1.00 319.20 ? 449 VAL B CA  1 
ATOM   6624  C C   . VAL B 2 449 ? 85.857  106.921 95.682  1.00 262.14 ? 449 VAL B C   1 
ATOM   6625  O O   . VAL B 2 449 ? 86.248  107.561 96.660  1.00 223.80 ? 449 VAL B O   1 
ATOM   6626  C CB  . VAL B 2 449 ? 84.379  104.861 95.990  1.00 307.81 ? 449 VAL B CB  1 
ATOM   6627  C CG1 . VAL B 2 449 ? 85.243  104.496 97.190  1.00 287.69 ? 449 VAL B CG1 1 
ATOM   6628  C CG2 . VAL B 2 449 ? 82.941  104.406 96.212  1.00 308.72 ? 449 VAL B CG2 1 
ATOM   6629  N N   . SER B 2 450 ? 86.615  106.678 94.605  1.00 253.03 ? 450 SER B N   1 
ATOM   6630  C CA  . SER B 2 450 ? 88.042  106.966 94.553  1.00 288.04 ? 450 SER B CA  1 
ATOM   6631  C C   . SER B 2 450 ? 88.370  108.457 94.588  1.00 275.28 ? 450 SER B C   1 
ATOM   6632  O O   . SER B 2 450 ? 89.441  108.798 95.072  1.00 230.56 ? 450 SER B O   1 
ATOM   6633  C CB  . SER B 2 450 ? 88.653  106.323 93.347  1.00 311.70 ? 450 SER B CB  1 
ATOM   6634  O OG  . SER B 2 450 ? 88.443  104.925 93.439  1.00 347.78 ? 450 SER B OG  1 
ATOM   6635  N N   . PHE B 2 451 ? 87.483  109.333 94.090  1.00 284.69 ? 451 PHE B N   1 
ATOM   6636  C CA  . PHE B 2 451 ? 87.643  110.780 94.223  1.00 309.49 ? 451 PHE B CA  1 
ATOM   6637  C C   . PHE B 2 451 ? 87.953  111.216 95.660  1.00 372.61 ? 451 PHE B C   1 
ATOM   6638  O O   . PHE B 2 451 ? 88.770  112.119 95.837  1.00 298.77 ? 451 PHE B O   1 
ATOM   6639  C CB  . PHE B 2 451 ? 86.386  111.518 93.746  1.00 334.14 ? 451 PHE B CB  1 
ATOM   6640  C CG  . PHE B 2 451 ? 86.405  111.963 92.305  1.00 328.57 ? 451 PHE B CG  1 
ATOM   6641  C CD1 . PHE B 2 451 ? 87.216  113.026 91.918  1.00 310.13 ? 451 PHE B CD1 1 
ATOM   6642  C CD2 . PHE B 2 451 ? 85.619  111.331 91.341  1.00 350.86 ? 451 PHE B CD2 1 
ATOM   6643  C CE1 . PHE B 2 451 ? 87.240  113.449 90.596  1.00 382.07 ? 451 PHE B CE1 1 
ATOM   6644  C CE2 . PHE B 2 451 ? 85.646  111.758 90.018  1.00 365.06 ? 451 PHE B CE2 1 
ATOM   6645  C CZ  . PHE B 2 451 ? 86.456  112.816 89.648  1.00 390.92 ? 451 PHE B CZ  1 
ATOM   6646  N N   . TRP B 2 452 ? 87.300  110.589 96.660  1.00 466.75 ? 452 TRP B N   1 
ATOM   6647  C CA  . TRP B 2 452 ? 87.456  110.938 98.071  1.00 489.65 ? 452 TRP B CA  1 
ATOM   6648  C C   . TRP B 2 452 ? 88.294  109.919 98.858  1.00 469.90 ? 452 TRP B C   1 
ATOM   6649  O O   . TRP B 2 452 ? 88.897  110.306 99.860  1.00 465.40 ? 452 TRP B O   1 
ATOM   6650  C CB  . TRP B 2 452 ? 86.066  111.170 98.686  1.00 447.35 ? 452 TRP B CB  1 
ATOM   6651  C CG  . TRP B 2 452 ? 85.369  112.359 98.075  1.00 437.51 ? 452 TRP B CG  1 
ATOM   6652  C CD1 . TRP B 2 452 ? 85.715  113.662 98.270  1.00 395.58 ? 452 TRP B CD1 1 
ATOM   6653  C CD2 . TRP B 2 452 ? 84.231  112.372 97.173  1.00 458.25 ? 452 TRP B CD2 1 
ATOM   6654  N NE1 . TRP B 2 452 ? 84.873  114.490 97.570  1.00 387.52 ? 452 TRP B NE1 1 
ATOM   6655  C CE2 . TRP B 2 452 ? 83.953  113.734 96.885  1.00 438.14 ? 452 TRP B CE2 1 
ATOM   6656  C CE3 . TRP B 2 452 ? 83.416  111.388 96.584  1.00 461.46 ? 452 TRP B CE3 1 
ATOM   6657  C CZ2 . TRP B 2 452 ? 82.904  114.119 96.038  1.00 427.52 ? 452 TRP B CZ2 1 
ATOM   6658  C CZ3 . TRP B 2 452 ? 82.380  111.770 95.750  1.00 430.68 ? 452 TRP B CZ3 1 
ATOM   6659  C CH2 . TRP B 2 452 ? 82.130  113.121 95.482  1.00 410.74 ? 452 TRP B CH2 1 
ATOM   6660  N N   . LYS B 2 453 ? 88.370  108.644 98.428  1.00 410.85 ? 453 LYS B N   1 
ATOM   6661  C CA  . LYS B 2 453 ? 89.240  107.675 99.091  1.00 360.89 ? 453 LYS B CA  1 
ATOM   6662  C C   . LYS B 2 453 ? 90.719  107.918 98.753  1.00 343.85 ? 453 LYS B C   1 
ATOM   6663  O O   . LYS B 2 453 ? 91.573  107.680 99.610  1.00 346.64 ? 453 LYS B O   1 
ATOM   6664  C CB  . LYS B 2 453 ? 88.850  106.229 98.752  1.00 327.50 ? 453 LYS B CB  1 
ATOM   6665  C CG  . LYS B 2 453 ? 88.732  105.307 99.958  1.00 339.40 ? 453 LYS B CG  1 
ATOM   6666  C CD  . LYS B 2 453 ? 89.927  105.258 100.904 1.00 339.64 ? 453 LYS B CD  1 
ATOM   6667  C CE  . LYS B 2 453 ? 89.683  104.390 102.120 1.00 329.81 ? 453 LYS B CE  1 
ATOM   6668  N NZ  . LYS B 2 453 ? 90.739  104.583 103.141 1.00 352.43 ? 453 LYS B NZ  1 
ATOM   6669  N N   . THR B 2 454 ? 91.024  108.382 97.523  1.00 304.93 ? 454 THR B N   1 
ATOM   6670  C CA  . THR B 2 454 ? 92.390  108.641 97.067  1.00 353.30 ? 454 THR B CA  1 
ATOM   6671  C C   . THR B 2 454 ? 92.442  109.961 96.291  1.00 323.53 ? 454 THR B C   1 
ATOM   6672  O O   . THR B 2 454 ? 92.651  109.963 95.073  1.00 398.74 ? 454 THR B O   1 
ATOM   6673  C CB  . THR B 2 454 ? 92.935  107.467 96.234  1.00 430.10 ? 454 THR B CB  1 
ATOM   6674  O OG1 . THR B 2 454 ? 92.056  107.183 95.142  1.00 437.25 ? 454 THR B OG1 1 
ATOM   6675  C CG2 . THR B 2 454 ? 93.126  106.207 97.050  1.00 484.97 ? 454 THR B CG2 1 
ATOM   6676  N N   . PRO B 2 455 ? 92.260  111.129 96.952  1.00 281.81 ? 455 PRO B N   1 
ATOM   6677  C CA  . PRO B 2 455 ? 92.171  112.406 96.237  1.00 309.75 ? 455 PRO B CA  1 
ATOM   6678  C C   . PRO B 2 455 ? 93.442  112.868 95.512  1.00 312.58 ? 455 PRO B C   1 
ATOM   6679  O O   . PRO B 2 455 ? 93.343  113.353 94.388  1.00 336.61 ? 455 PRO B O   1 
ATOM   6680  C CB  . PRO B 2 455 ? 91.813  113.416 97.348  1.00 374.15 ? 455 PRO B CB  1 
ATOM   6681  C CG  . PRO B 2 455 ? 91.310  112.572 98.500  1.00 360.05 ? 455 PRO B CG  1 
ATOM   6682  C CD  . PRO B 2 455 ? 92.121  111.300 98.408  1.00 311.38 ? 455 PRO B CD  1 
ATOM   6683  N N   . VAL B 2 456 ? 94.622  112.720 96.141  1.00 290.88 ? 456 VAL B N   1 
ATOM   6684  C CA  . VAL B 2 456 ? 95.842  113.392 95.688  1.00 329.64 ? 456 VAL B CA  1 
ATOM   6685  C C   . VAL B 2 456 ? 96.349  112.803 94.360  1.00 367.35 ? 456 VAL B C   1 
ATOM   6686  O O   . VAL B 2 456 ? 96.851  113.551 93.511  1.00 291.78 ? 456 VAL B O   1 
ATOM   6687  C CB  . VAL B 2 456 ? 96.930  113.399 96.788  1.00 335.75 ? 456 VAL B CB  1 
ATOM   6688  C CG1 . VAL B 2 456 ? 97.455  112.009 97.150  1.00 344.14 ? 456 VAL B CG1 1 
ATOM   6689  C CG2 . VAL B 2 456 ? 98.084  114.321 96.414  1.00 348.23 ? 456 VAL B CG2 1 
ATOM   6690  N N   . GLU B 2 457 ? 96.215  111.476 94.176  1.00 414.90 ? 457 GLU B N   1 
ATOM   6691  C CA  . GLU B 2 457 ? 96.555  110.806 92.923  1.00 432.75 ? 457 GLU B CA  1 
ATOM   6692  C C   . GLU B 2 457 ? 95.652  111.291 91.775  1.00 335.25 ? 457 GLU B C   1 
ATOM   6693  O O   . GLU B 2 457 ? 96.138  111.606 90.685  1.00 372.52 ? 457 GLU B O   1 
ATOM   6694  C CB  . GLU B 2 457 ? 96.504  109.282 93.114  1.00 469.37 ? 457 GLU B CB  1 
ATOM   6695  C CG  . GLU B 2 457 ? 97.605  108.715 94.023  1.00 471.70 ? 457 GLU B CG  1 
ATOM   6696  C CD  . GLU B 2 457 ? 99.029  108.713 93.476  1.00 470.10 ? 457 GLU B CD  1 
ATOM   6697  O OE1 . GLU B 2 457 ? 99.270  109.323 92.414  1.00 455.17 ? 457 GLU B OE1 1 
ATOM   6698  O OE2 . GLU B 2 457 ? 99.907  108.081 94.113  1.00 458.14 ? 457 GLU B OE2 1 
ATOM   6699  N N   . CYS B 2 458 ? 94.340  111.373 92.011  1.00 229.68 ? 458 CYS B N   1 
ATOM   6700  C CA  . CYS B 2 458 ? 93.430  111.944 91.025  1.00 235.73 ? 458 CYS B CA  1 
ATOM   6701  C C   . CYS B 2 458 ? 93.767  113.407 90.718  1.00 259.39 ? 458 CYS B C   1 
ATOM   6702  O O   . CYS B 2 458 ? 93.685  113.818 89.571  1.00 217.58 ? 458 CYS B O   1 
ATOM   6703  C CB  . CYS B 2 458 ? 91.990  111.811 91.495  1.00 264.81 ? 458 CYS B CB  1 
ATOM   6704  S SG  . CYS B 2 458 ? 91.603  110.091 91.884  1.00 366.51 ? 458 CYS B SG  1 
ATOM   6705  N N   . GLY B 2 459 ? 94.157  114.202 91.723  1.00 331.53 ? 459 GLY B N   1 
ATOM   6706  C CA  . GLY B 2 459 ? 94.511  115.601 91.520  1.00 352.66 ? 459 GLY B CA  1 
ATOM   6707  C C   . GLY B 2 459 ? 95.669  115.796 90.538  1.00 310.71 ? 459 GLY B C   1 
ATOM   6708  O O   . GLY B 2 459 ? 95.553  116.603 89.613  1.00 283.09 ? 459 GLY B O   1 
ATOM   6709  N N   . ILE B 2 460 ? 96.773  115.056 90.742  1.00 252.13 ? 460 ILE B N   1 
ATOM   6710  C CA  . ILE B 2 460 ? 97.924  115.160 89.849  1.00 293.49 ? 460 ILE B CA  1 
ATOM   6711  C C   . ILE B 2 460 ? 97.566  114.577 88.470  1.00 256.17 ? 460 ILE B C   1 
ATOM   6712  O O   . ILE B 2 460 ? 98.018  115.097 87.445  1.00 261.36 ? 460 ILE B O   1 
ATOM   6713  C CB  . ILE B 2 460 ? 99.208  114.568 90.491  1.00 325.18 ? 460 ILE B CB  1 
ATOM   6714  C CG1 . ILE B 2 460 ? 100.483 114.899 89.697  1.00 346.38 ? 460 ILE B CG1 1 
ATOM   6715  C CG2 . ILE B 2 460 ? 99.103  113.072 90.731  1.00 313.22 ? 460 ILE B CG2 1 
ATOM   6716  C CD1 . ILE B 2 460 ? 100.860 116.371 89.646  1.00 290.43 ? 460 ILE B CD1 1 
ATOM   6717  N N   . GLY B 2 461 ? 96.739  113.526 88.418  1.00 236.83 ? 461 GLY B N   1 
ATOM   6718  C CA  . GLY B 2 461 ? 96.262  112.993 87.145  1.00 239.78 ? 461 GLY B CA  1 
ATOM   6719  C C   . GLY B 2 461 ? 95.372  113.954 86.352  1.00 237.60 ? 461 GLY B C   1 
ATOM   6720  O O   . GLY B 2 461 ? 95.590  114.135 85.160  1.00 254.32 ? 461 GLY B O   1 
ATOM   6721  N N   . PHE B 2 462 ? 94.369  114.578 86.987  1.00 219.69 ? 462 PHE B N   1 
ATOM   6722  C CA  . PHE B 2 462 ? 93.574  115.594 86.314  1.00 202.88 ? 462 PHE B CA  1 
ATOM   6723  C C   . PHE B 2 462 ? 94.439  116.804 85.945  1.00 222.22 ? 462 PHE B C   1 
ATOM   6724  O O   . PHE B 2 462 ? 94.117  117.466 84.967  1.00 265.27 ? 462 PHE B O   1 
ATOM   6725  C CB  . PHE B 2 462 ? 92.347  115.960 87.157  1.00 257.32 ? 462 PHE B CB  1 
ATOM   6726  C CG  . PHE B 2 462 ? 91.235  114.948 87.069  1.00 277.09 ? 462 PHE B CG  1 
ATOM   6727  C CD1 . PHE B 2 462 ? 90.591  114.721 85.857  1.00 268.10 ? 462 PHE B CD1 1 
ATOM   6728  C CD2 . PHE B 2 462 ? 90.829  114.220 88.184  1.00 281.46 ? 462 PHE B CD2 1 
ATOM   6729  C CE1 . PHE B 2 462 ? 89.562  113.789 85.763  1.00 291.32 ? 462 PHE B CE1 1 
ATOM   6730  C CE2 . PHE B 2 462 ? 89.801  113.284 88.091  1.00 316.06 ? 462 PHE B CE2 1 
ATOM   6731  C CZ  . PHE B 2 462 ? 89.169  113.069 86.880  1.00 314.89 ? 462 PHE B CZ  1 
ATOM   6732  N N   . THR B 2 463 ? 95.518  117.108 86.692  1.00 226.70 ? 463 THR B N   1 
ATOM   6733  C CA  . THR B 2 463 ? 96.479  118.136 86.288  1.00 268.77 ? 463 THR B CA  1 
ATOM   6734  C C   . THR B 2 463 ? 97.156  117.764 84.959  1.00 236.57 ? 463 THR B C   1 
ATOM   6735  O O   . THR B 2 463 ? 97.346  118.643 84.117  1.00 254.64 ? 463 THR B O   1 
ATOM   6736  C CB  . THR B 2 463 ? 97.483  118.439 87.415  1.00 325.48 ? 463 THR B CB  1 
ATOM   6737  O OG1 . THR B 2 463 ? 96.731  118.898 88.543  1.00 289.80 ? 463 THR B OG1 1 
ATOM   6738  C CG2 . THR B 2 463 ? 98.539  119.460 87.041  1.00 333.80 ? 463 THR B CG2 1 
ATOM   6739  N N   . ILE B 2 464 ? 97.507  116.483 84.754  1.00 235.57 ? 464 ILE B N   1 
ATOM   6740  C CA  . ILE B 2 464 ? 97.989  115.996 83.459  1.00 255.53 ? 464 ILE B CA  1 
ATOM   6741  C C   . ILE B 2 464 ? 96.920  116.165 82.362  1.00 248.22 ? 464 ILE B C   1 
ATOM   6742  O O   . ILE B 2 464 ? 97.243  116.665 81.286  1.00 291.93 ? 464 ILE B O   1 
ATOM   6743  C CB  . ILE B 2 464 ? 98.495  114.540 83.551  1.00 261.49 ? 464 ILE B CB  1 
ATOM   6744  C CG1 . ILE B 2 464 ? 99.713  114.421 84.472  1.00 312.52 ? 464 ILE B CG1 1 
ATOM   6745  C CG2 . ILE B 2 464 ? 98.799  113.958 82.169  1.00 270.18 ? 464 ILE B CG2 1 
ATOM   6746  C CD1 . ILE B 2 464 ? 99.938  113.024 85.015  1.00 335.59 ? 464 ILE B CD1 1 
ATOM   6747  N N   . ILE B 2 465 ? 95.665  115.768 82.617  1.00 228.69 ? 465 ILE B N   1 
ATOM   6748  C CA  . ILE B 2 465 ? 94.580  115.880 81.641  1.00 244.66 ? 465 ILE B CA  1 
ATOM   6749  C C   . ILE B 2 465 ? 94.387  117.341 81.224  1.00 304.01 ? 465 ILE B C   1 
ATOM   6750  O O   . ILE B 2 465 ? 94.372  117.621 80.025  1.00 311.11 ? 465 ILE B O   1 
ATOM   6751  C CB  . ILE B 2 465 ? 93.273  115.249 82.179  1.00 280.80 ? 465 ILE B CB  1 
ATOM   6752  C CG1 . ILE B 2 465 ? 93.440  113.731 82.270  1.00 346.01 ? 465 ILE B CG1 1 
ATOM   6753  C CG2 . ILE B 2 465 ? 92.041  115.637 81.355  1.00 272.90 ? 465 ILE B CG2 1 
ATOM   6754  C CD1 . ILE B 2 465 ? 92.332  112.997 82.976  1.00 332.04 ? 465 ILE B CD1 1 
ATOM   6755  N N   . LEU B 2 466 ? 94.248  118.263 82.196  1.00 331.23 ? 466 LEU B N   1 
ATOM   6756  C CA  . LEU B 2 466 ? 94.029  119.678 81.901  1.00 320.68 ? 466 LEU B CA  1 
ATOM   6757  C C   . LEU B 2 466 ? 95.239  120.279 81.168  1.00 290.15 ? 466 LEU B C   1 
ATOM   6758  O O   . LEU B 2 466 ? 95.040  121.141 80.318  1.00 282.45 ? 466 LEU B O   1 
ATOM   6759  C CB  . LEU B 2 466 ? 93.676  120.433 83.193  1.00 311.39 ? 466 LEU B CB  1 
ATOM   6760  C CG  . LEU B 2 466 ? 92.357  120.029 83.866  1.00 334.64 ? 466 LEU B CG  1 
ATOM   6761  C CD1 . LEU B 2 466 ? 92.184  120.759 85.189  1.00 323.59 ? 466 LEU B CD1 1 
ATOM   6762  C CD2 . LEU B 2 466 ? 91.144  120.275 82.974  1.00 364.56 ? 466 LEU B CD2 1 
ATOM   6763  N N   . SER B 2 467 ? 96.474  119.816 81.444  1.00 320.66 ? 467 SER B N   1 
ATOM   6764  C CA  . SER B 2 467 ? 97.654  120.220 80.671  1.00 326.71 ? 467 SER B CA  1 
ATOM   6765  C C   . SER B 2 467 ? 97.635  119.730 79.212  1.00 264.01 ? 467 SER B C   1 
ATOM   6766  O O   . SER B 2 467 ? 98.476  120.149 78.424  1.00 216.18 ? 467 SER B O   1 
ATOM   6767  C CB  . SER B 2 467 ? 98.946  119.795 81.351  1.00 353.27 ? 467 SER B CB  1 
ATOM   6768  O OG  . SER B 2 467 ? 99.267  118.435 81.088  1.00 364.89 ? 467 SER B OG  1 
ATOM   6769  N N   . GLY B 2 468 ? 96.699  118.848 78.840  1.00 263.37 ? 468 GLY B N   1 
ATOM   6770  C CA  . GLY B 2 468 ? 96.458  118.474 77.451  1.00 296.15 ? 468 GLY B CA  1 
ATOM   6771  C C   . GLY B 2 468 ? 95.711  119.517 76.615  1.00 301.84 ? 468 GLY B C   1 
ATOM   6772  O O   . GLY B 2 468 ? 95.827  119.522 75.393  1.00 268.74 ? 468 GLY B O   1 
ATOM   6773  N N   . LEU B 2 469 ? 94.944  120.408 77.250  1.00 291.19 ? 469 LEU B N   1 
ATOM   6774  C CA  . LEU B 2 469 ? 94.118  121.351 76.506  1.00 267.55 ? 469 LEU B CA  1 
ATOM   6775  C C   . LEU B 2 469 ? 95.002  122.377 75.776  1.00 274.18 ? 469 LEU B C   1 
ATOM   6776  O O   . LEU B 2 469 ? 94.758  122.613 74.593  1.00 277.56 ? 469 LEU B O   1 
ATOM   6777  C CB  . LEU B 2 469 ? 93.099  121.990 77.465  1.00 323.01 ? 469 LEU B CB  1 
ATOM   6778  C CG  . LEU B 2 469 ? 92.144  121.024 78.171  1.00 321.58 ? 469 LEU B CG  1 
ATOM   6779  C CD1 . LEU B 2 469 ? 91.194  121.768 79.098  1.00 369.07 ? 469 LEU B CD1 1 
ATOM   6780  C CD2 . LEU B 2 469 ? 91.353  120.218 77.164  1.00 290.93 ? 469 LEU B CD2 1 
ATOM   6781  N N   . PRO B 2 470 ? 96.039  123.016 76.396  1.00 303.09 ? 470 PRO B N   1 
ATOM   6782  C CA  . PRO B 2 470 ? 97.015  123.832 75.659  1.00 317.42 ? 470 PRO B CA  1 
ATOM   6783  C C   . PRO B 2 470 ? 97.594  123.170 74.409  1.00 291.65 ? 470 PRO B C   1 
ATOM   6784  O O   . PRO B 2 470 ? 97.532  123.767 73.340  1.00 329.54 ? 470 PRO B O   1 
ATOM   6785  C CB  . PRO B 2 470 ? 98.120  124.090 76.700  1.00 317.71 ? 470 PRO B CB  1 
ATOM   6786  C CG  . PRO B 2 470 ? 97.347  124.168 77.985  1.00 314.34 ? 470 PRO B CG  1 
ATOM   6787  C CD  . PRO B 2 470 ? 96.347  123.041 77.837  1.00 311.65 ? 470 PRO B CD  1 
ATOM   6788  N N   . VAL B 2 471 ? 98.133  121.951 74.531  1.00 232.43 ? 471 VAL B N   1 
ATOM   6789  C CA  . VAL B 2 471 ? 98.769  121.284 73.395  1.00 262.47 ? 471 VAL B CA  1 
ATOM   6790  C C   . VAL B 2 471 ? 97.747  120.805 72.354  1.00 266.34 ? 471 VAL B C   1 
ATOM   6791  O O   . VAL B 2 471 ? 98.121  120.662 71.188  1.00 272.99 ? 471 VAL B O   1 
ATOM   6792  C CB  . VAL B 2 471 ? 99.717  120.148 73.828  1.00 260.29 ? 471 VAL B CB  1 
ATOM   6793  C CG1 . VAL B 2 471 ? 100.981 120.729 74.454  1.00 236.52 ? 471 VAL B CG1 1 
ATOM   6794  C CG2 . VAL B 2 471 ? 99.058  119.123 74.747  1.00 323.17 ? 471 VAL B CG2 1 
ATOM   6795  N N   . TYR B 2 472 ? 96.480  120.580 72.733  1.00 278.23 ? 472 TYR B N   1 
ATOM   6796  C CA  . TYR B 2 472 ? 95.424  120.355 71.748  1.00 318.79 ? 472 TYR B CA  1 
ATOM   6797  C C   . TYR B 2 472 ? 95.187  121.613 70.892  1.00 283.66 ? 472 TYR B C   1 
ATOM   6798  O O   . TYR B 2 472 ? 95.157  121.540 69.659  1.00 194.20 ? 472 TYR B O   1 
ATOM   6799  C CB  . TYR B 2 472 ? 94.122  119.891 72.414  1.00 320.47 ? 472 TYR B CB  1 
ATOM   6800  C CG  . TYR B 2 472 ? 93.046  119.668 71.360  1.00 283.30 ? 472 TYR B CG  1 
ATOM   6801  C CD1 . TYR B 2 472 ? 93.175  118.630 70.430  1.00 271.22 ? 472 TYR B CD1 1 
ATOM   6802  C CD2 . TYR B 2 472 ? 91.927  120.494 71.277  1.00 256.66 ? 472 TYR B CD2 1 
ATOM   6803  C CE1 . TYR B 2 472 ? 92.218  118.415 69.449  1.00 185.03 ? 472 TYR B CE1 1 
ATOM   6804  C CE2 . TYR B 2 472 ? 90.967  120.281 70.297  1.00 294.20 ? 472 TYR B CE2 1 
ATOM   6805  C CZ  . TYR B 2 472 ? 91.111  119.242 69.384  1.00 253.11 ? 472 TYR B CZ  1 
ATOM   6806  O OH  . TYR B 2 472 ? 90.157  119.049 68.423  1.00 303.78 ? 472 TYR B OH  1 
ATOM   6807  N N   . PHE B 2 473 ? 95.015  122.774 71.540  1.00 279.77 ? 473 PHE B N   1 
ATOM   6808  C CA  . PHE B 2 473 ? 94.772  124.016 70.819  1.00 268.63 ? 473 PHE B CA  1 
ATOM   6809  C C   . PHE B 2 473 ? 95.988  124.374 69.958  1.00 269.25 ? 473 PHE B C   1 
ATOM   6810  O O   . PHE B 2 473 ? 95.837  124.539 68.751  1.00 296.70 ? 473 PHE B O   1 
ATOM   6811  C CB  . PHE B 2 473 ? 94.377  125.136 71.789  1.00 334.83 ? 473 PHE B CB  1 
ATOM   6812  C CG  . PHE B 2 473 ? 93.078  124.929 72.532  1.00 401.91 ? 473 PHE B CG  1 
ATOM   6813  C CD1 . PHE B 2 473 ? 91.936  124.449 71.890  1.00 448.02 ? 473 PHE B CD1 1 
ATOM   6814  C CD2 . PHE B 2 473 ? 92.994  125.216 73.890  1.00 400.45 ? 473 PHE B CD2 1 
ATOM   6815  C CE1 . PHE B 2 473 ? 90.749  124.260 72.589  1.00 427.58 ? 473 PHE B CE1 1 
ATOM   6816  C CE2 . PHE B 2 473 ? 91.802  125.037 74.585  1.00 395.48 ? 473 PHE B CE2 1 
ATOM   6817  C CZ  . PHE B 2 473 ? 90.682  124.558 73.934  1.00 389.74 ? 473 PHE B CZ  1 
ATOM   6818  N N   . PHE B 2 474 ? 97.177  124.485 70.569  1.00 245.38 ? 474 PHE B N   1 
ATOM   6819  C CA  . PHE B 2 474 ? 98.418  124.844 69.879  1.00 286.47 ? 474 PHE B CA  1 
ATOM   6820  C C   . PHE B 2 474 ? 98.796  123.843 68.770  1.00 305.58 ? 474 PHE B C   1 
ATOM   6821  O O   . PHE B 2 474 ? 99.298  124.249 67.716  1.00 268.02 ? 474 PHE B O   1 
ATOM   6822  C CB  . PHE B 2 474 ? 99.533  124.998 70.925  1.00 255.45 ? 474 PHE B CB  1 
ATOM   6823  C CG  . PHE B 2 474 ? 100.940 125.141 70.392  1.00 321.10 ? 474 PHE B CG  1 
ATOM   6824  C CD1 . PHE B 2 474 ? 101.720 124.027 70.074  1.00 376.29 ? 474 PHE B CD1 1 
ATOM   6825  C CD2 . PHE B 2 474 ? 101.495 126.400 70.207  1.00 335.74 ? 474 PHE B CD2 1 
ATOM   6826  C CE1 . PHE B 2 474 ? 103.012 124.169 69.583  1.00 355.46 ? 474 PHE B CE1 1 
ATOM   6827  C CE2 . PHE B 2 474 ? 102.790 126.544 69.715  1.00 409.02 ? 474 PHE B CE2 1 
ATOM   6828  C CZ  . PHE B 2 474 ? 103.546 125.428 69.406  1.00 402.68 ? 474 PHE B CZ  1 
ATOM   6829  N N   . GLY B 2 475 ? 98.566  122.542 69.004  1.00 340.02 ? 475 GLY B N   1 
ATOM   6830  C CA  . GLY B 2 475 ? 99.062  121.488 68.125  1.00 345.06 ? 475 GLY B CA  1 
ATOM   6831  C C   . GLY B 2 475 ? 98.082  121.033 67.040  1.00 345.80 ? 475 GLY B C   1 
ATOM   6832  O O   . GLY B 2 475 ? 98.531  120.489 66.031  1.00 295.87 ? 475 GLY B O   1 
ATOM   6833  N N   . VAL B 2 476 ? 96.760  121.225 67.239  1.00 348.01 ? 476 VAL B N   1 
ATOM   6834  C CA  . VAL B 2 476 ? 95.740  120.603 66.389  1.00 360.33 ? 476 VAL B CA  1 
ATOM   6835  C C   . VAL B 2 476 ? 94.643  121.596 65.973  1.00 442.14 ? 476 VAL B C   1 
ATOM   6836  O O   . VAL B 2 476 ? 94.375  121.707 64.778  1.00 518.39 ? 476 VAL B O   1 
ATOM   6837  C CB  . VAL B 2 476 ? 95.144  119.345 67.059  1.00 292.12 ? 476 VAL B CB  1 
ATOM   6838  C CG1 . VAL B 2 476 ? 94.017  118.718 66.241  1.00 290.42 ? 476 VAL B CG1 1 
ATOM   6839  C CG2 . VAL B 2 476 ? 96.220  118.299 67.348  1.00 365.87 ? 476 VAL B CG2 1 
ATOM   6840  N N   . TRP B 2 477 ? 93.994  122.298 66.918  1.00 443.16 ? 477 TRP B N   1 
ATOM   6841  C CA  . TRP B 2 477 ? 92.731  122.992 66.651  1.00 446.65 ? 477 TRP B CA  1 
ATOM   6842  C C   . TRP B 2 477 ? 92.911  124.449 66.190  1.00 382.11 ? 477 TRP B C   1 
ATOM   6843  O O   . TRP B 2 477 ? 92.199  124.883 65.283  1.00 258.73 ? 477 TRP B O   1 
ATOM   6844  C CB  . TRP B 2 477 ? 91.834  122.907 67.897  1.00 492.23 ? 477 TRP B CB  1 
ATOM   6845  C CG  . TRP B 2 477 ? 90.485  123.577 67.759  1.00 497.26 ? 477 TRP B CG  1 
ATOM   6846  C CD1 . TRP B 2 477 ? 89.319  122.973 67.383  1.00 450.69 ? 477 TRP B CD1 1 
ATOM   6847  C CD2 . TRP B 2 477 ? 90.155  124.971 68.007  1.00 476.44 ? 477 TRP B CD2 1 
ATOM   6848  N NE1 . TRP B 2 477 ? 88.291  123.882 67.371  1.00 400.06 ? 477 TRP B NE1 1 
ATOM   6849  C CE2 . TRP B 2 477 ? 88.767  125.115 67.750  1.00 432.16 ? 477 TRP B CE2 1 
ATOM   6850  C CE3 . TRP B 2 477 ? 90.886  126.104 68.417  1.00 432.66 ? 477 TRP B CE3 1 
ATOM   6851  C CZ2 . TRP B 2 477 ? 88.108  126.344 67.891  1.00 385.36 ? 477 TRP B CZ2 1 
ATOM   6852  C CZ3 . TRP B 2 477 ? 90.232  127.315 68.556  1.00 385.86 ? 477 TRP B CZ3 1 
ATOM   6853  C CH2 . TRP B 2 477 ? 88.861  127.429 68.296  1.00 386.89 ? 477 TRP B CH2 1 
ATOM   6854  N N   . TRP B 2 478 ? 93.831  125.204 66.813  1.00 398.97 ? 478 TRP B N   1 
ATOM   6855  C CA  . TRP B 2 478 ? 94.062  126.614 66.495  1.00 428.61 ? 478 TRP B CA  1 
ATOM   6856  C C   . TRP B 2 478 ? 94.936  126.768 65.237  1.00 427.43 ? 478 TRP B C   1 
ATOM   6857  O O   . TRP B 2 478 ? 94.809  127.772 64.532  1.00 430.63 ? 478 TRP B O   1 
ATOM   6858  C CB  . TRP B 2 478 ? 94.666  127.318 67.728  1.00 469.92 ? 478 TRP B CB  1 
ATOM   6859  C CG  . TRP B 2 478 ? 94.648  128.834 67.749  1.00 470.89 ? 478 TRP B CG  1 
ATOM   6860  C CD1 . TRP B 2 478 ? 94.026  129.679 66.873  1.00 452.18 ? 478 TRP B CD1 1 
ATOM   6861  C CD2 . TRP B 2 478 ? 95.298  129.697 68.724  1.00 459.25 ? 478 TRP B CD2 1 
ATOM   6862  N NE1 . TRP B 2 478 ? 94.240  130.987 67.224  1.00 424.75 ? 478 TRP B NE1 1 
ATOM   6863  C CE2 . TRP B 2 478 ? 95.016  131.036 68.355  1.00 438.66 ? 478 TRP B CE2 1 
ATOM   6864  C CE3 . TRP B 2 478 ? 96.089  129.480 69.869  1.00 417.22 ? 478 TRP B CE3 1 
ATOM   6865  C CZ2 . TRP B 2 478 ? 95.494  132.131 69.088  1.00 400.02 ? 478 TRP B CZ2 1 
ATOM   6866  C CZ3 . TRP B 2 478 ? 96.561  130.562 70.592  1.00 342.66 ? 478 TRP B CZ3 1 
ATOM   6867  C CH2 . TRP B 2 478 ? 96.266  131.872 70.204  1.00 348.69 ? 478 TRP B CH2 1 
ATOM   6868  N N   . LYS B 2 479 ? 95.819  125.782 64.961  1.00 421.05 ? 479 LYS B N   1 
ATOM   6869  C CA  . LYS B 2 479 ? 96.640  125.690 63.750  1.00 413.01 ? 479 LYS B CA  1 
ATOM   6870  C C   . LYS B 2 479 ? 97.445  126.976 63.528  1.00 408.78 ? 479 LYS B C   1 
ATOM   6871  O O   . LYS B 2 479 ? 97.410  127.555 62.444  1.00 396.66 ? 479 LYS B O   1 
ATOM   6872  C CB  . LYS B 2 479 ? 95.785  125.349 62.517  1.00 394.40 ? 479 LYS B CB  1 
ATOM   6873  C CG  . LYS B 2 479 ? 94.969  124.066 62.612  1.00 422.20 ? 479 LYS B CG  1 
ATOM   6874  C CD  . LYS B 2 479 ? 94.259  123.715 61.321  1.00 407.21 ? 479 LYS B CD  1 
ATOM   6875  C CE  . LYS B 2 479 ? 93.166  122.680 61.495  1.00 423.94 ? 479 LYS B CE  1 
ATOM   6876  N NZ  . LYS B 2 479 ? 93.687  121.384 61.995  1.00 429.01 ? 479 LYS B NZ  1 
ATOM   6877  N N   . ASN B 2 480 ? 98.181  127.402 64.565  1.00 386.76 ? 480 ASN B N   1 
ATOM   6878  C CA  . ASN B 2 480 ? 98.797  128.726 64.621  1.00 377.43 ? 480 ASN B CA  1 
ATOM   6879  C C   . ASN B 2 480 ? 99.638  129.013 63.365  1.00 440.11 ? 480 ASN B C   1 
ATOM   6880  O O   . ASN B 2 480 ? 100.605 128.312 63.062  1.00 403.48 ? 480 ASN B O   1 
ATOM   6881  C CB  . ASN B 2 480 ? 99.600  128.911 65.915  1.00 342.54 ? 480 ASN B CB  1 
ATOM   6882  C CG  . ASN B 2 480 ? 98.699  129.008 67.128  1.00 314.59 ? 480 ASN B CG  1 
ATOM   6883  O OD1 . ASN B 2 480 ? 97.998  128.048 67.448  1.00 362.69 ? 480 ASN B OD1 1 
ATOM   6884  N ND2 . ASN B 2 480 ? 98.705  130.147 67.805  1.00 287.97 ? 480 ASN B ND2 1 
ATOM   6885  N N   . LYS B 2 481 ? 99.244  130.080 62.651  1.00 481.13 ? 481 LYS B N   1 
ATOM   6886  C CA  . LYS B 2 481 ? 99.679  130.386 61.292  1.00 493.73 ? 481 LYS B CA  1 
ATOM   6887  C C   . LYS B 2 481 ? 101.104 130.955 61.147  1.00 485.64 ? 481 LYS B C   1 
ATOM   6888  O O   . LYS B 2 481 ? 101.651 130.795 60.052  1.00 446.76 ? 481 LYS B O   1 
ATOM   6889  C CB  . LYS B 2 481 ? 98.695  131.396 60.682  1.00 468.61 ? 481 LYS B CB  1 
ATOM   6890  C CG  . LYS B 2 481 ? 97.247  130.931 60.541  1.00 412.61 ? 481 LYS B CG  1 
ATOM   6891  C CD  . LYS B 2 481 ? 97.023  129.802 59.550  1.00 406.41 ? 481 LYS B CD  1 
ATOM   6892  C CE  . LYS B 2 481 ? 97.365  130.153 58.117  1.00 448.12 ? 481 LYS B CE  1 
ATOM   6893  N NZ  . LYS B 2 481 ? 97.008  129.057 57.187  1.00 465.10 ? 481 LYS B NZ  1 
ATOM   6894  N N   . PRO B 2 482 ? 101.756 131.639 62.138  1.00 446.09 ? 482 PRO B N   1 
ATOM   6895  C CA  . PRO B 2 482 ? 103.067 132.277 61.920  1.00 403.25 ? 482 PRO B CA  1 
ATOM   6896  C C   . PRO B 2 482 ? 104.163 131.405 61.287  1.00 384.17 ? 482 PRO B C   1 
ATOM   6897  O O   . PRO B 2 482 ? 104.443 130.288 61.736  1.00 372.12 ? 482 PRO B O   1 
ATOM   6898  C CB  . PRO B 2 482 ? 103.506 132.721 63.334  1.00 388.90 ? 482 PRO B CB  1 
ATOM   6899  C CG  . PRO B 2 482 ? 102.198 132.983 64.036  1.00 365.91 ? 482 PRO B CG  1 
ATOM   6900  C CD  . PRO B 2 482 ? 101.286 131.890 63.513  1.00 425.08 ? 482 PRO B CD  1 
ATOM   6901  N N   . LYS B 2 483 ? 104.787 131.950 60.230  1.00 378.40 ? 483 LYS B N   1 
ATOM   6902  C CA  . LYS B 2 483 ? 105.771 131.234 59.430  1.00 402.02 ? 483 LYS B CA  1 
ATOM   6903  C C   . LYS B 2 483 ? 107.051 130.979 60.239  1.00 446.90 ? 483 LYS B C   1 
ATOM   6904  O O   . LYS B 2 483 ? 107.666 129.931 60.052  1.00 488.28 ? 483 LYS B O   1 
ATOM   6905  C CB  . LYS B 2 483 ? 106.041 132.001 58.127  1.00 431.47 ? 483 LYS B CB  1 
ATOM   6906  C CG  . LYS B 2 483 ? 106.782 131.233 57.035  1.00 476.24 ? 483 LYS B CG  1 
ATOM   6907  C CD  . LYS B 2 483 ? 106.116 129.926 56.635  1.00 529.35 ? 483 LYS B CD  1 
ATOM   6908  C CE  . LYS B 2 483 ? 106.475 129.437 55.244  1.00 554.86 ? 483 LYS B CE  1 
ATOM   6909  N NZ  . LYS B 2 483 ? 107.904 129.071 55.113  1.00 568.83 ? 483 LYS B NZ  1 
ATOM   6910  N N   . TRP B 2 484 ? 107.445 131.905 61.135  1.00 462.65 ? 484 TRP B N   1 
ATOM   6911  C CA  . TRP B 2 484 ? 108.573 131.693 62.046  1.00 443.93 ? 484 TRP B CA  1 
ATOM   6912  C C   . TRP B 2 484 ? 108.334 130.498 62.982  1.00 471.07 ? 484 TRP B C   1 
ATOM   6913  O O   . TRP B 2 484 ? 109.277 129.751 63.264  1.00 413.49 ? 484 TRP B O   1 
ATOM   6914  C CB  . TRP B 2 484 ? 108.912 132.971 62.843  1.00 404.20 ? 484 TRP B CB  1 
ATOM   6915  C CG  . TRP B 2 484 ? 107.793 133.556 63.675  1.00 421.23 ? 484 TRP B CG  1 
ATOM   6916  C CD1 . TRP B 2 484 ? 107.018 134.619 63.309  1.00 420.23 ? 484 TRP B CD1 1 
ATOM   6917  C CD2 . TRP B 2 484 ? 107.317 133.150 64.986  1.00 430.17 ? 484 TRP B CD2 1 
ATOM   6918  N NE1 . TRP B 2 484 ? 106.097 134.904 64.283  1.00 401.57 ? 484 TRP B NE1 1 
ATOM   6919  C CE2 . TRP B 2 484 ? 106.251 134.025 65.325  1.00 407.60 ? 484 TRP B CE2 1 
ATOM   6920  C CE3 . TRP B 2 484 ? 107.673 132.146 65.906  1.00 419.57 ? 484 TRP B CE3 1 
ATOM   6921  C CZ2 . TRP B 2 484 ? 105.550 133.921 66.532  1.00 366.12 ? 484 TRP B CZ2 1 
ATOM   6922  C CZ3 . TRP B 2 484 ? 106.978 132.040 67.096  1.00 404.65 ? 484 TRP B CZ3 1 
ATOM   6923  C CH2 . TRP B 2 484 ? 105.934 132.922 67.406  1.00 380.74 ? 484 TRP B CH2 1 
ATOM   6924  N N   . LEU B 2 485 ? 107.084 130.314 63.452  1.00 514.93 ? 485 LEU B N   1 
ATOM   6925  C CA  . LEU B 2 485 ? 106.723 129.199 64.322  1.00 486.20 ? 485 LEU B CA  1 
ATOM   6926  C C   . LEU B 2 485 ? 106.834 127.885 63.542  1.00 452.11 ? 485 LEU B C   1 
ATOM   6927  O O   . LEU B 2 485 ? 107.465 126.945 64.029  1.00 477.40 ? 485 LEU B O   1 
ATOM   6928  C CB  . LEU B 2 485 ? 105.313 129.424 64.891  1.00 462.09 ? 485 LEU B CB  1 
ATOM   6929  C CG  . LEU B 2 485 ? 104.785 128.362 65.858  1.00 406.39 ? 485 LEU B CG  1 
ATOM   6930  C CD1 . LEU B 2 485 ? 105.572 128.372 67.160  1.00 403.40 ? 485 LEU B CD1 1 
ATOM   6931  C CD2 . LEU B 2 485 ? 103.300 128.570 66.134  1.00 375.36 ? 485 LEU B CD2 1 
ATOM   6932  N N   . LEU B 2 486 ? 106.243 127.834 62.336  1.00 411.51 ? 486 LEU B N   1 
ATOM   6933  C CA  . LEU B 2 486 ? 106.293 126.645 61.491  1.00 414.02 ? 486 LEU B CA  1 
ATOM   6934  C C   . LEU B 2 486 ? 107.741 126.275 61.116  1.00 410.68 ? 486 LEU B C   1 
ATOM   6935  O O   . LEU B 2 486 ? 108.082 125.092 61.158  1.00 403.07 ? 486 LEU B O   1 
ATOM   6936  C CB  . LEU B 2 486 ? 105.400 126.868 60.260  1.00 418.40 ? 486 LEU B CB  1 
ATOM   6937  C CG  . LEU B 2 486 ? 105.336 125.726 59.242  1.00 411.86 ? 486 LEU B CG  1 
ATOM   6938  C CD1 . LEU B 2 486 ? 104.823 124.439 59.869  1.00 413.02 ? 486 LEU B CD1 1 
ATOM   6939  C CD2 . LEU B 2 486 ? 104.461 126.111 58.064  1.00 419.19 ? 486 LEU B CD2 1 
ATOM   6940  N N   . GLN B 2 487 ? 108.598 127.253 60.766  1.00 426.75 ? 487 GLN B N   1 
ATOM   6941  C CA  . GLN B 2 487 ? 110.013 126.987 60.499  1.00 434.13 ? 487 GLN B CA  1 
ATOM   6942  C C   . GLN B 2 487 ? 110.765 126.526 61.755  1.00 435.27 ? 487 GLN B C   1 
ATOM   6943  O O   . GLN B 2 487 ? 111.695 125.727 61.624  1.00 479.78 ? 487 GLN B O   1 
ATOM   6944  C CB  . GLN B 2 487 ? 110.713 128.206 59.883  1.00 445.41 ? 487 GLN B CB  1 
ATOM   6945  C CG  . GLN B 2 487 ? 110.279 128.550 58.459  1.00 477.10 ? 487 GLN B CG  1 
ATOM   6946  C CD  . GLN B 2 487 ? 110.322 127.413 57.463  1.00 481.60 ? 487 GLN B CD  1 
ATOM   6947  O OE1 . GLN B 2 487 ? 109.369 127.189 56.716  1.00 493.73 ? 487 GLN B OE1 1 
ATOM   6948  N NE2 . GLN B 2 487 ? 111.429 126.687 57.436  1.00 459.01 ? 487 GLN B NE2 1 
ATOM   6949  N N   . GLY B 2 488 ? 110.378 127.008 62.951  1.00 403.04 ? 488 GLY B N   1 
ATOM   6950  C CA  . GLY B 2 488 ? 110.921 126.515 64.213  1.00 400.52 ? 488 GLY B CA  1 
ATOM   6951  C C   . GLY B 2 488 ? 110.565 125.050 64.488  1.00 391.13 ? 488 GLY B C   1 
ATOM   6952  O O   . GLY B 2 488 ? 111.442 124.258 64.851  1.00 384.98 ? 488 GLY B O   1 
ATOM   6953  N N   . ILE B 2 489 ? 109.275 124.710 64.307  1.00 379.13 ? 489 ILE B N   1 
ATOM   6954  C CA  . ILE B 2 489 ? 108.759 123.344 64.402  1.00 354.93 ? 489 ILE B CA  1 
ATOM   6955  C C   . ILE B 2 489 ? 109.512 122.442 63.415  1.00 305.13 ? 489 ILE B C   1 
ATOM   6956  O O   . ILE B 2 489 ? 109.970 121.368 63.802  1.00 275.28 ? 489 ILE B O   1 
ATOM   6957  C CB  . ILE B 2 489 ? 107.221 123.332 64.197  1.00 401.49 ? 489 ILE B CB  1 
ATOM   6958  C CG1 . ILE B 2 489 ? 106.502 123.972 65.391  1.00 466.59 ? 489 ILE B CG1 1 
ATOM   6959  C CG2 . ILE B 2 489 ? 106.667 121.932 63.913  1.00 336.06 ? 489 ILE B CG2 1 
ATOM   6960  C CD1 . ILE B 2 489 ? 105.069 124.397 65.123  1.00 494.33 ? 489 ILE B CD1 1 
ATOM   6961  N N   . PHE B 2 490 ? 109.638 122.881 62.152  1.00 303.35 ? 490 PHE B N   1 
ATOM   6962  C CA  . PHE B 2 490 ? 110.350 122.129 61.124  1.00 307.43 ? 490 PHE B CA  1 
ATOM   6963  C C   . PHE B 2 490 ? 111.822 121.923 61.510  1.00 257.69 ? 490 PHE B C   1 
ATOM   6964  O O   . PHE B 2 490 ? 112.320 120.801 61.427  1.00 257.98 ? 490 PHE B O   1 
ATOM   6965  C CB  . PHE B 2 490 ? 110.181 122.791 59.750  1.00 318.59 ? 490 PHE B CB  1 
ATOM   6966  C CG  . PHE B 2 490 ? 110.714 121.940 58.624  1.00 321.87 ? 490 PHE B CG  1 
ATOM   6967  C CD1 . PHE B 2 490 ? 112.039 122.054 58.224  1.00 337.41 ? 490 PHE B CD1 1 
ATOM   6968  C CD2 . PHE B 2 490 ? 109.905 121.005 57.981  1.00 310.76 ? 490 PHE B CD2 1 
ATOM   6969  C CE1 . PHE B 2 490 ? 112.537 121.265 57.193  1.00 360.39 ? 490 PHE B CE1 1 
ATOM   6970  C CE2 . PHE B 2 490 ? 110.405 120.213 56.955  1.00 322.77 ? 490 PHE B CE2 1 
ATOM   6971  C CZ  . PHE B 2 490 ? 111.721 120.346 56.560  1.00 349.09 ? 490 PHE B CZ  1 
ATOM   6972  N N   . SER B 2 491 ? 112.507 122.989 61.943  1.00 336.61 ? 491 SER B N   1 
ATOM   6973  C CA  . SER B 2 491 ? 113.906 122.910 62.366  1.00 362.50 ? 491 SER B CA  1 
ATOM   6974  C C   . SER B 2 491 ? 114.096 121.908 63.514  1.00 361.03 ? 491 SER B C   1 
ATOM   6975  O O   . SER B 2 491 ? 115.030 121.102 63.479  1.00 263.94 ? 491 SER B O   1 
ATOM   6976  C CB  . SER B 2 491 ? 114.442 124.279 62.741  1.00 376.58 ? 491 SER B CB  1 
ATOM   6977  O OG  . SER B 2 491 ? 114.358 125.184 61.648  1.00 346.86 ? 491 SER B OG  1 
ATOM   6978  N N   . THR B 2 492 ? 113.210 121.964 64.525  1.00 390.07 ? 492 THR B N   1 
ATOM   6979  C CA  . THR B 2 492 ? 113.202 121.021 65.640  1.00 364.00 ? 492 THR B CA  1 
ATOM   6980  C C   . THR B 2 492 ? 113.015 119.584 65.141  1.00 279.15 ? 492 THR B C   1 
ATOM   6981  O O   . THR B 2 492 ? 113.697 118.675 65.609  1.00 223.97 ? 492 THR B O   1 
ATOM   6982  C CB  . THR B 2 492 ? 112.114 121.392 66.664  1.00 421.25 ? 492 THR B CB  1 
ATOM   6983  O OG1 . THR B 2 492 ? 112.324 122.735 67.111  1.00 339.72 ? 492 THR B OG1 1 
ATOM   6984  C CG2 . THR B 2 492 ? 112.078 120.488 67.877  1.00 496.07 ? 492 THR B CG2 1 
ATOM   6985  N N   . THR B 2 493 ? 112.085 119.386 64.196  1.00 278.59 ? 493 THR B N   1 
ATOM   6986  C CA  . THR B 2 493 ? 111.814 118.081 63.603  1.00 280.60 ? 493 THR B CA  1 
ATOM   6987  C C   . THR B 2 493 ? 113.042 117.535 62.868  1.00 248.22 ? 493 THR B C   1 
ATOM   6988  O O   . THR B 2 493 ? 113.457 116.420 63.160  1.00 209.26 ? 493 THR B O   1 
ATOM   6989  C CB  . THR B 2 493 ? 110.585 118.133 62.681  1.00 298.95 ? 493 THR B CB  1 
ATOM   6990  O OG1 . THR B 2 493 ? 109.462 118.541 63.466  1.00 313.56 ? 493 THR B OG1 1 
ATOM   6991  C CG2 . THR B 2 493 ? 110.267 116.816 62.003  1.00 279.18 ? 493 THR B CG2 1 
ATOM   6992  N N   . VAL B 2 494 ? 113.628 118.298 61.930  1.00 293.91 ? 494 VAL B N   1 
ATOM   6993  C CA  . VAL B 2 494 ? 114.743 117.778 61.139  1.00 303.86 ? 494 VAL B CA  1 
ATOM   6994  C C   . VAL B 2 494 ? 115.974 117.557 62.021  1.00 263.31 ? 494 VAL B C   1 
ATOM   6995  O O   . VAL B 2 494 ? 116.753 116.655 61.726  1.00 217.34 ? 494 VAL B O   1 
ATOM   6996  C CB  . VAL B 2 494 ? 115.087 118.630 59.893  1.00 347.21 ? 494 VAL B CB  1 
ATOM   6997  C CG1 . VAL B 2 494 ? 113.897 118.709 58.957  1.00 371.24 ? 494 VAL B CG1 1 
ATOM   6998  C CG2 . VAL B 2 494 ? 115.608 120.029 60.204  1.00 336.57 ? 494 VAL B CG2 1 
ATOM   6999  N N   . LEU B 2 495 ? 116.158 118.355 63.083  1.00 257.20 ? 495 LEU B N   1 
ATOM   7000  C CA  . LEU B 2 495 ? 117.206 118.090 64.059  1.00 301.39 ? 495 LEU B CA  1 
ATOM   7001  C C   . LEU B 2 495 ? 117.054 116.664 64.593  1.00 269.54 ? 495 LEU B C   1 
ATOM   7002  O O   . LEU B 2 495 ? 118.019 115.910 64.549  1.00 206.07 ? 495 LEU B O   1 
ATOM   7003  C CB  . LEU B 2 495 ? 117.143 119.158 65.162  1.00 359.56 ? 495 LEU B CB  1 
ATOM   7004  C CG  . LEU B 2 495 ? 118.018 118.947 66.394  1.00 406.28 ? 495 LEU B CG  1 
ATOM   7005  C CD1 . LEU B 2 495 ? 119.492 118.878 66.020  1.00 408.66 ? 495 LEU B CD1 1 
ATOM   7006  C CD2 . LEU B 2 495 ? 117.776 120.072 67.396  1.00 362.00 ? 495 LEU B CD2 1 
ATOM   7007  N N   . CYS B 2 496 ? 115.858 116.304 65.082  1.00 286.55 ? 496 CYS B N   1 
ATOM   7008  C CA  . CYS B 2 496 ? 115.596 114.962 65.591  1.00 282.66 ? 496 CYS B CA  1 
ATOM   7009  C C   . CYS B 2 496 ? 115.805 113.907 64.502  1.00 218.30 ? 496 CYS B C   1 
ATOM   7010  O O   . CYS B 2 496 ? 116.403 112.864 64.781  1.00 196.49 ? 496 CYS B O   1 
ATOM   7011  C CB  . CYS B 2 496 ? 114.186 114.866 66.174  1.00 343.44 ? 496 CYS B CB  1 
ATOM   7012  S SG  . CYS B 2 496 ? 113.924 115.993 67.567  1.00 374.90 ? 496 CYS B SG  1 
ATOM   7013  N N   . GLN B 2 497 ? 115.325 114.171 63.274  1.00 215.12 ? 497 GLN B N   1 
ATOM   7014  C CA  . GLN B 2 497 ? 115.489 113.234 62.175  1.00 207.34 ? 497 GLN B CA  1 
ATOM   7015  C C   . GLN B 2 497 ? 116.970 112.951 61.924  1.00 233.09 ? 497 GLN B C   1 
ATOM   7016  O O   . GLN B 2 497 ? 117.332 111.788 61.777  1.00 168.40 ? 497 GLN B O   1 
ATOM   7017  C CB  . GLN B 2 497 ? 114.836 113.745 60.894  1.00 228.56 ? 497 GLN B CB  1 
ATOM   7018  C CG  . GLN B 2 497 ? 113.323 113.769 60.935  1.00 237.73 ? 497 GLN B CG  1 
ATOM   7019  C CD  . GLN B 2 497 ? 112.726 113.886 59.556  1.00 315.80 ? 497 GLN B CD  1 
ATOM   7020  O OE1 . GLN B 2 497 ? 112.266 114.952 59.154  1.00 376.81 ? 497 GLN B OE1 1 
ATOM   7021  N NE2 . GLN B 2 497 ? 112.739 112.792 58.809  1.00 332.40 ? 497 GLN B NE2 1 
ATOM   7022  N N   . LYS B 2 498 ? 117.808 114.002 61.880  1.00 271.41 ? 498 LYS B N   1 
ATOM   7023  C CA  . LYS B 2 498 ? 119.241 113.872 61.635  1.00 305.39 ? 498 LYS B CA  1 
ATOM   7024  C C   . LYS B 2 498 ? 119.949 113.205 62.819  1.00 274.23 ? 498 LYS B C   1 
ATOM   7025  O O   . LYS B 2 498 ? 120.869 112.409 62.610  1.00 235.05 ? 498 LYS B O   1 
ATOM   7026  C CB  . LYS B 2 498 ? 119.846 115.247 61.318  1.00 300.44 ? 498 LYS B CB  1 
ATOM   7027  C CG  . LYS B 2 498 ? 119.430 115.827 59.972  1.00 334.56 ? 498 LYS B CG  1 
ATOM   7028  C CD  . LYS B 2 498 ? 119.998 117.203 59.659  1.00 375.58 ? 498 LYS B CD  1 
ATOM   7029  C CE  . LYS B 2 498 ? 119.446 118.335 60.503  1.00 384.10 ? 498 LYS B CE  1 
ATOM   7030  N NZ  . LYS B 2 498 ? 119.994 119.650 60.077  1.00 322.23 ? 498 LYS B NZ  1 
ATOM   7031  N N   . LEU B 2 499 ? 119.513 113.522 64.049  1.00 243.90 ? 499 LEU B N   1 
ATOM   7032  C CA  . LEU B 2 499 ? 120.153 113.050 65.273  1.00 241.66 ? 499 LEU B CA  1 
ATOM   7033  C C   . LEU B 2 499 ? 119.756 111.616 65.639  1.00 239.83 ? 499 LEU B C   1 
ATOM   7034  O O   . LEU B 2 499 ? 120.463 111.010 66.440  1.00 231.23 ? 499 LEU B O   1 
ATOM   7035  C CB  . LEU B 2 499 ? 119.797 114.047 66.387  1.00 247.59 ? 499 LEU B CB  1 
ATOM   7036  C CG  . LEU B 2 499 ? 120.564 113.947 67.703  1.00 310.72 ? 499 LEU B CG  1 
ATOM   7037  C CD1 . LEU B 2 499 ? 122.080 113.915 67.502  1.00 318.14 ? 499 LEU B CD1 1 
ATOM   7038  C CD2 . LEU B 2 499 ? 120.178 115.129 68.594  1.00 295.68 ? 499 LEU B CD2 1 
ATOM   7039  N N   . MET B 2 500 ? 118.658 111.070 65.078  1.00 269.62 ? 500 MET B N   1 
ATOM   7040  C CA  . MET B 2 500 ? 118.296 109.661 65.245  1.00 282.15 ? 500 MET B CA  1 
ATOM   7041  C C   . MET B 2 500 ? 118.369 108.859 63.932  1.00 258.98 ? 500 MET B C   1 
ATOM   7042  O O   . MET B 2 500 ? 118.245 107.635 63.988  1.00 262.23 ? 500 MET B O   1 
ATOM   7043  C CB  . MET B 2 500 ? 116.879 109.565 65.830  1.00 312.15 ? 500 MET B CB  1 
ATOM   7044  C CG  . MET B 2 500 ? 116.742 110.212 67.210  1.00 311.55 ? 500 MET B CG  1 
ATOM   7045  S SD  . MET B 2 500 ? 115.080 110.003 67.975  1.00 244.60 ? 500 MET B SD  1 
ATOM   7046  C CE  . MET B 2 500 ? 115.016 111.445 69.043  1.00 274.30 ? 500 MET B CE  1 
ATOM   7047  N N   . GLN B 2 501 ? 118.567 109.519 62.770  1.00 249.98 ? 501 GLN B N   1 
ATOM   7048  C CA  . GLN B 2 501 ? 118.539 108.919 61.435  1.00 311.97 ? 501 GLN B CA  1 
ATOM   7049  C C   . GLN B 2 501 ? 117.191 108.216 61.203  1.00 304.16 ? 501 GLN B C   1 
ATOM   7050  O O   . GLN B 2 501 ? 117.133 106.992 61.149  1.00 290.33 ? 501 GLN B O   1 
ATOM   7051  C CB  . GLN B 2 501 ? 119.776 108.019 61.250  1.00 369.76 ? 501 GLN B CB  1 
ATOM   7052  C CG  . GLN B 2 501 ? 119.945 107.424 59.853  1.00 400.61 ? 501 GLN B CG  1 
ATOM   7053  C CD  . GLN B 2 501 ? 121.285 106.748 59.655  1.00 366.18 ? 501 GLN B CD  1 
ATOM   7054  O OE1 . GLN B 2 501 ? 122.341 107.323 59.910  1.00 349.22 ? 501 GLN B OE1 1 
ATOM   7055  N NE2 . GLN B 2 501 ? 121.254 105.501 59.209  1.00 338.09 ? 501 GLN B NE2 1 
ATOM   7056  N N   . VAL B 2 502 ? 116.107 109.001 61.077  1.00 264.20 ? 502 VAL B N   1 
ATOM   7057  C CA  . VAL B 2 502 ? 114.760 108.454 60.918  1.00 258.11 ? 502 VAL B CA  1 
ATOM   7058  C C   . VAL B 2 502 ? 113.953 109.167 59.831  1.00 272.39 ? 502 VAL B C   1 
ATOM   7059  O O   . VAL B 2 502 ? 114.115 110.362 59.575  1.00 261.29 ? 502 VAL B O   1 
ATOM   7060  C CB  . VAL B 2 502 ? 113.959 108.462 62.239  1.00 231.88 ? 502 VAL B CB  1 
ATOM   7061  C CG1 . VAL B 2 502 ? 114.654 107.606 63.276  1.00 261.83 ? 502 VAL B CG1 1 
ATOM   7062  C CG2 . VAL B 2 502 ? 113.687 109.853 62.796  1.00 206.44 ? 502 VAL B CG2 1 
ATOM   7063  N N   . VAL B 2 503 ? 113.031 108.390 59.230  1.00 259.94 ? 503 VAL B N   1 
ATOM   7064  C CA  . VAL B 2 503 ? 112.310 108.737 58.017  1.00 219.05 ? 503 VAL B CA  1 
ATOM   7065  C C   . VAL B 2 503 ? 110.836 108.357 58.164  1.00 237.93 ? 503 VAL B C   1 
ATOM   7066  O O   . VAL B 2 503 ? 110.500 107.453 58.937  1.00 345.58 ? 503 VAL B O   1 
ATOM   7067  C CB  . VAL B 2 503 ? 112.927 108.009 56.808  1.00 269.93 ? 503 VAL B CB  1 
ATOM   7068  C CG1 . VAL B 2 503 ? 114.420 108.288 56.698  1.00 356.48 ? 503 VAL B CG1 1 
ATOM   7069  C CG2 . VAL B 2 503 ? 112.668 106.498 56.806  1.00 195.70 ? 503 VAL B CG2 1 
ATOM   7070  N N   . PRO B 2 504 ? 109.909 109.025 57.438  1.00 274.22 ? 504 PRO B N   1 
ATOM   7071  C CA  . PRO B 2 504 ? 108.510 108.582 57.358  1.00 330.20 ? 504 PRO B CA  1 
ATOM   7072  C C   . PRO B 2 504 ? 108.280 107.149 56.852  1.00 296.66 ? 504 PRO B C   1 
ATOM   7073  O O   . PRO B 2 504 ? 109.066 106.609 56.072  1.00 204.70 ? 504 PRO B O   1 
ATOM   7074  C CB  . PRO B 2 504 ? 107.868 109.588 56.380  1.00 358.21 ? 504 PRO B CB  1 
ATOM   7075  C CG  . PRO B 2 504 ? 108.741 110.814 56.475  1.00 335.35 ? 504 PRO B CG  1 
ATOM   7076  C CD  . PRO B 2 504 ? 110.136 110.270 56.693  1.00 304.41 ? 504 PRO B CD  1 
ATOM   7077  N N   . GLN B 2 505 ? 107.183 106.550 57.334  1.00 317.17 ? 505 GLN B N   1 
ATOM   7078  C CA  . GLN B 2 505 ? 106.673 105.272 56.849  1.00 382.49 ? 505 GLN B CA  1 
ATOM   7079  C C   . GLN B 2 505 ? 105.973 105.469 55.497  1.00 408.51 ? 505 GLN B C   1 
ATOM   7080  O O   . GLN B 2 505 ? 105.547 106.577 55.167  1.00 431.45 ? 505 GLN B O   1 
ATOM   7081  C CB  . GLN B 2 505 ? 105.752 104.634 57.906  1.00 427.36 ? 505 GLN B CB  1 
ATOM   7082  C CG  . GLN B 2 505 ? 104.272 105.048 57.892  1.00 460.32 ? 505 GLN B CG  1 
ATOM   7083  C CD  . GLN B 2 505 ? 103.987 106.521 58.081  1.00 437.73 ? 505 GLN B CD  1 
ATOM   7084  O OE1 . GLN B 2 505 ? 104.816 107.271 58.591  1.00 425.62 ? 505 GLN B OE1 1 
ATOM   7085  N NE2 . GLN B 2 505 ? 102.800 106.954 57.678  1.00 425.21 ? 505 GLN B NE2 1 
ATOM   7086  N N   . GLU B 2 506 ? 105.840 104.376 54.718  1.00 423.56 ? 506 GLU B N   1 
ATOM   7087  C CA  . GLU B 2 506 ? 105.121 104.408 53.446  1.00 426.50 ? 506 GLU B CA  1 
ATOM   7088  C C   . GLU B 2 506 ? 103.627 104.678 53.677  1.00 488.36 ? 506 GLU B C   1 
ATOM   7089  O O   . GLU B 2 506 ? 102.940 103.862 54.294  1.00 511.98 ? 506 GLU B O   1 
ATOM   7090  C CB  . GLU B 2 506 ? 105.308 103.100 52.670  1.00 423.70 ? 506 GLU B CB  1 
ATOM   7091  C CG  . GLU B 2 506 ? 106.745 102.838 52.232  1.00 431.74 ? 506 GLU B CG  1 
ATOM   7092  C CD  . GLU B 2 506 ? 107.589 101.962 53.146  1.00 437.13 ? 506 GLU B CD  1 
ATOM   7093  O OE1 . GLU B 2 506 ? 107.430 102.055 54.375  1.00 452.29 ? 506 GLU B OE1 1 
ATOM   7094  O OE2 . GLU B 2 506 ? 108.416 101.185 52.620  1.00 409.45 ? 506 GLU B OE2 1 
ATOM   7095  N N   . THR B 2 507 ? 103.129 105.829 53.177  1.00 507.44 ? 507 THR B N   1 
ATOM   7096  C CA  . THR B 2 507 ? 101.740 106.256 53.361  1.00 487.00 ? 507 THR B CA  1 
ATOM   7097  C C   . THR B 2 507 ? 100.793 105.323 52.584  1.00 434.15 ? 507 THR B C   1 
ATOM   7098  O O   . THR B 2 507 ? 100.915 105.238 51.339  1.00 376.48 ? 507 THR B O   1 
ATOM   7099  C CB  . THR B 2 507 ? 101.557 107.742 52.990  1.00 450.24 ? 507 THR B CB  1 
ATOM   7100  O OG1 . THR B 2 507 ? 102.391 108.537 53.836  1.00 402.55 ? 507 THR B OG1 1 
ATOM   7101  C CG2 . THR B 2 507 ? 100.139 108.254 53.138  1.00 420.55 ? 507 THR B CG2 1 
ATOM   7102  N N   . ASP C 3 1   ? 96.609  120.263 131.483 1.00 256.56 ? 1   ASP L N   1 
ATOM   7103  C CA  . ASP C 3 1   ? 96.729  120.068 132.953 1.00 219.01 ? 1   ASP L CA  1 
ATOM   7104  C C   . ASP C 3 1   ? 95.384  120.331 133.617 1.00 153.07 ? 1   ASP L C   1 
ATOM   7105  O O   . ASP C 3 1   ? 94.528  121.006 133.070 1.00 203.59 ? 1   ASP L O   1 
ATOM   7106  C CB  . ASP C 3 1   ? 97.812  120.982 133.557 1.00 286.38 ? 1   ASP L CB  1 
ATOM   7107  C CG  . ASP C 3 1   ? 99.205  120.843 132.945 1.00 348.67 ? 1   ASP L CG  1 
ATOM   7108  O OD1 . ASP C 3 1   ? 99.323  120.194 131.883 1.00 381.48 ? 1   ASP L OD1 1 
ATOM   7109  O OD2 . ASP C 3 1   ? 100.170 121.384 133.532 1.00 347.97 ? 1   ASP L OD2 1 
ATOM   7110  N N   . ILE C 3 2   ? 95.210  119.811 134.832 1.00 125.62 ? 2   ILE L N   1 
ATOM   7111  C CA  . ILE C 3 2   ? 94.145  120.241 135.745 1.00 88.88  ? 2   ILE L CA  1 
ATOM   7112  C C   . ILE C 3 2   ? 94.319  121.715 136.135 1.00 108.60 ? 2   ILE L C   1 
ATOM   7113  O O   . ILE C 3 2   ? 95.437  122.234 136.161 1.00 139.22 ? 2   ILE L O   1 
ATOM   7114  C CB  . ILE C 3 2   ? 94.089  119.308 136.970 1.00 81.55  ? 2   ILE L CB  1 
ATOM   7115  C CG1 . ILE C 3 2   ? 93.645  117.928 136.506 1.00 123.34 ? 2   ILE L CG1 1 
ATOM   7116  C CG2 . ILE C 3 2   ? 93.183  119.782 138.120 1.00 70.00  ? 2   ILE L CG2 1 
ATOM   7117  C CD1 . ILE C 3 2   ? 93.931  116.827 137.473 1.00 157.18 ? 2   ILE L CD1 1 
ATOM   7118  N N   . VAL C 3 3   ? 93.181  122.385 136.394 1.00 120.66 ? 3   VAL L N   1 
ATOM   7119  C CA  . VAL C 3 3   ? 93.136  123.761 136.854 1.00 125.73 ? 3   VAL L CA  1 
ATOM   7120  C C   . VAL C 3 3   ? 92.288  123.803 138.104 1.00 106.57 ? 3   VAL L C   1 
ATOM   7121  O O   . VAL C 3 3   ? 91.206  123.206 138.093 1.00 122.85 ? 3   VAL L O   1 
ATOM   7122  C CB  . VAL C 3 3   ? 92.570  124.702 135.783 1.00 173.24 ? 3   VAL L CB  1 
ATOM   7123  C CG1 . VAL C 3 3   ? 92.425  126.125 136.318 1.00 281.85 ? 3   VAL L CG1 1 
ATOM   7124  C CG2 . VAL C 3 3   ? 93.410  124.650 134.513 1.00 224.11 ? 3   VAL L CG2 1 
ATOM   7125  N N   . LEU C 3 4   ? 92.807  124.508 139.144 1.00 110.88 ? 4   LEU L N   1 
ATOM   7126  C CA  . LEU C 3 4   ? 92.098  124.605 140.413 1.00 119.88 ? 4   LEU L CA  1 
ATOM   7127  C C   . LEU C 3 4   ? 91.714  126.049 140.707 1.00 121.33 ? 4   LEU L C   1 
ATOM   7128  O O   . LEU C 3 4   ? 92.550  126.858 141.028 1.00 150.92 ? 4   LEU L O   1 
ATOM   7129  C CB  . LEU C 3 4   ? 92.909  123.933 141.525 1.00 109.41 ? 4   LEU L CB  1 
ATOM   7130  C CG  . LEU C 3 4   ? 92.994  122.392 141.380 1.00 112.32 ? 4   LEU L CG  1 
ATOM   7131  C CD1 . LEU C 3 4   ? 94.336  122.054 140.812 1.00 160.21 ? 4   LEU L CD1 1 
ATOM   7132  C CD2 . LEU C 3 4   ? 92.770  121.613 142.690 1.00 79.87  ? 4   LEU L CD2 1 
ATOM   7133  N N   . THR C 3 5   ? 90.419  126.348 140.550 1.00 127.06 ? 5   THR L N   1 
ATOM   7134  C CA  . THR C 3 5   ? 89.840  127.609 140.951 1.00 141.41 ? 5   THR L CA  1 
ATOM   7135  C C   . THR C 3 5   ? 89.675  127.572 142.466 1.00 106.64 ? 5   THR L C   1 
ATOM   7136  O O   . THR C 3 5   ? 89.299  126.559 143.034 1.00 94.58  ? 5   THR L O   1 
ATOM   7137  C CB  . THR C 3 5   ? 88.489  127.830 140.253 1.00 263.85 ? 5   THR L CB  1 
ATOM   7138  O OG1 . THR C 3 5   ? 88.706  127.870 138.839 1.00 300.62 ? 5   THR L OG1 1 
ATOM   7139  C CG2 . THR C 3 5   ? 87.765  129.094 140.679 1.00 330.06 ? 5   THR L CG2 1 
ATOM   7140  N N   . GLN C 3 6   ? 89.961  128.685 143.112 1.00 111.20 ? 6   GLN L N   1 
ATOM   7141  C CA  . GLN C 3 6   ? 89.792  128.795 144.544 1.00 117.32 ? 6   GLN L CA  1 
ATOM   7142  C C   . GLN C 3 6   ? 89.019  130.065 144.891 1.00 173.14 ? 6   GLN L C   1 
ATOM   7143  O O   . GLN C 3 6   ? 89.217  131.113 144.270 1.00 267.35 ? 6   GLN L O   1 
ATOM   7144  C CB  . GLN C 3 6   ? 91.189  128.834 145.156 1.00 143.91 ? 6   GLN L CB  1 
ATOM   7145  C CG  . GLN C 3 6   ? 91.183  128.366 146.594 1.00 153.11 ? 6   GLN L CG  1 
ATOM   7146  C CD  . GLN C 3 6   ? 92.548  128.316 147.253 1.00 140.33 ? 6   GLN L CD  1 
ATOM   7147  O OE1 . GLN C 3 6   ? 93.559  127.869 146.703 1.00 76.19  ? 6   GLN L OE1 1 
ATOM   7148  N NE2 . GLN C 3 6   ? 92.595  128.794 148.484 1.00 165.64 ? 6   GLN L NE2 1 
ATOM   7149  N N   . SER C 3 7   ? 88.140  129.974 145.901 1.00 164.73 ? 7   SER L N   1 
ATOM   7150  C CA  . SER C 3 7   ? 87.341  131.130 146.321 1.00 148.66 ? 7   SER L CA  1 
ATOM   7151  C C   . SER C 3 7   ? 86.909  131.023 147.782 1.00 140.30 ? 7   SER L C   1 
ATOM   7152  O O   . SER C 3 7   ? 86.877  129.925 148.346 1.00 233.08 ? 7   SER L O   1 
ATOM   7153  C CB  . SER C 3 7   ? 86.132  131.317 145.430 1.00 183.55 ? 7   SER L CB  1 
ATOM   7154  O OG  . SER C 3 7   ? 85.139  130.331 145.672 1.00 173.16 ? 7   SER L OG  1 
ATOM   7155  N N   . PRO C 3 8   ? 86.601  132.142 148.477 1.00 141.62 ? 8   PRO L N   1 
ATOM   7156  C CA  . PRO C 3 8   ? 86.865  133.497 147.992 1.00 159.84 ? 8   PRO L CA  1 
ATOM   7157  C C   . PRO C 3 8   ? 88.362  133.804 148.048 1.00 168.83 ? 8   PRO L C   1 
ATOM   7158  O O   . PRO C 3 8   ? 89.109  133.117 148.749 1.00 253.13 ? 8   PRO L O   1 
ATOM   7159  C CB  . PRO C 3 8   ? 86.067  134.342 148.998 1.00 196.95 ? 8   PRO L CB  1 
ATOM   7160  C CG  . PRO C 3 8   ? 86.156  133.563 150.293 1.00 152.54 ? 8   PRO L CG  1 
ATOM   7161  C CD  . PRO C 3 8   ? 86.007  132.135 149.822 1.00 163.20 ? 8   PRO L CD  1 
ATOM   7162  N N   . SER C 3 9   ? 88.796  134.825 147.299 1.00 143.73 ? 9   SER L N   1 
ATOM   7163  C CA  . SER C 3 9   ? 90.192  135.243 147.307 1.00 182.11 ? 9   SER L CA  1 
ATOM   7164  C C   . SER C 3 9   ? 90.610  135.848 148.658 1.00 164.45 ? 9   SER L C   1 
ATOM   7165  O O   . SER C 3 9   ? 91.788  135.782 149.039 1.00 237.19 ? 9   SER L O   1 
ATOM   7166  C CB  . SER C 3 9   ? 90.459  136.194 146.178 1.00 222.38 ? 9   SER L CB  1 
ATOM   7167  O OG  . SER C 3 9   ? 89.699  137.383 146.334 1.00 261.17 ? 9   SER L OG  1 
ATOM   7168  N N   . SER C 3 10  ? 89.646  136.442 149.370 1.00 119.83 ? 10  SER L N   1 
ATOM   7169  C CA  . SER C 3 10  ? 89.836  137.006 150.691 1.00 147.62 ? 10  SER L CA  1 
ATOM   7170  C C   . SER C 3 10  ? 88.756  136.477 151.609 1.00 135.44 ? 10  SER L C   1 
ATOM   7171  O O   . SER C 3 10  ? 87.622  136.328 151.181 1.00 171.15 ? 10  SER L O   1 
ATOM   7172  C CB  . SER C 3 10  ? 89.805  138.541 150.657 1.00 209.76 ? 10  SER L CB  1 
ATOM   7173  O OG  . SER C 3 10  ? 89.674  139.124 151.958 1.00 190.25 ? 10  SER L OG  1 
ATOM   7174  N N   . LEU C 3 11  ? 89.090  136.228 152.864 1.00 133.42 ? 11  LEU L N   1 
ATOM   7175  C CA  . LEU C 3 11  ? 88.088  135.766 153.805 1.00 137.28 ? 11  LEU L CA  1 
ATOM   7176  C C   . LEU C 3 11  ? 88.341  136.419 155.149 1.00 142.71 ? 11  LEU L C   1 
ATOM   7177  O O   . LEU C 3 11  ? 88.960  135.808 156.016 1.00 261.68 ? 11  LEU L O   1 
ATOM   7178  C CB  . LEU C 3 11  ? 88.230  134.249 153.845 1.00 165.23 ? 11  LEU L CB  1 
ATOM   7179  C CG  . LEU C 3 11  ? 87.403  133.469 154.863 1.00 237.81 ? 11  LEU L CG  1 
ATOM   7180  C CD1 . LEU C 3 11  ? 85.917  133.774 154.725 1.00 318.62 ? 11  LEU L CD1 1 
ATOM   7181  C CD2 . LEU C 3 11  ? 87.669  131.984 154.672 1.00 274.51 ? 11  LEU L CD2 1 
ATOM   7182  N N   . ALA C 3 12  ? 87.867  137.659 155.320 1.00 154.50 ? 12  ALA L N   1 
ATOM   7183  C CA  . ALA C 3 12  ? 88.117  138.350 156.586 1.00 214.34 ? 12  ALA L CA  1 
ATOM   7184  C C   . ALA C 3 12  ? 87.150  137.778 157.622 1.00 131.56 ? 12  ALA L C   1 
ATOM   7185  O O   . ALA C 3 12  ? 85.945  137.796 157.360 1.00 167.94 ? 12  ALA L O   1 
ATOM   7186  C CB  . ALA C 3 12  ? 87.962  139.848 156.419 1.00 283.67 ? 12  ALA L CB  1 
ATOM   7187  N N   . MET C 3 13  ? 87.666  137.267 158.765 1.00 144.36 ? 13  MET L N   1 
ATOM   7188  C CA  . MET C 3 13  ? 86.826  136.694 159.821 1.00 187.04 ? 13  MET L CA  1 
ATOM   7189  C C   . MET C 3 13  ? 87.394  136.945 161.216 1.00 159.82 ? 13  MET L C   1 
ATOM   7190  O O   . MET C 3 13  ? 88.566  137.188 161.370 1.00 167.80 ? 13  MET L O   1 
ATOM   7191  C CB  . MET C 3 13  ? 86.569  135.195 159.620 1.00 150.90 ? 13  MET L CB  1 
ATOM   7192  C CG  . MET C 3 13  ? 85.328  134.959 158.695 1.00 280.31 ? 13  MET L CG  1 
ATOM   7193  S SD  . MET C 3 13  ? 83.677  135.625 159.179 1.00 423.88 ? 13  MET L SD  1 
ATOM   7194  C CE  . MET C 3 13  ? 83.273  134.719 160.666 1.00 323.84 ? 13  MET L CE  1 
ATOM   7195  N N   . SER C 3 14  ? 86.504  136.904 162.216 1.00 190.91 ? 14  SER L N   1 
ATOM   7196  C CA  . SER C 3 14  ? 86.798  137.325 163.581 1.00 200.78 ? 14  SER L CA  1 
ATOM   7197  C C   . SER C 3 14  ? 87.308  136.144 164.395 1.00 128.84 ? 14  SER L C   1 
ATOM   7198  O O   . SER C 3 14  ? 86.964  134.992 164.114 1.00 138.45 ? 14  SER L O   1 
ATOM   7199  C CB  . SER C 3 14  ? 85.578  137.915 164.257 1.00 251.95 ? 14  SER L CB  1 
ATOM   7200  O OG  . SER C 3 14  ? 84.990  138.940 163.477 1.00 221.74 ? 14  SER L OG  1 
ATOM   7201  N N   . VAL C 3 15  ? 88.098  136.449 165.439 1.00 142.07 ? 15  VAL L N   1 
ATOM   7202  C CA  . VAL C 3 15  ? 88.741  135.418 166.246 1.00 149.88 ? 15  VAL L CA  1 
ATOM   7203  C C   . VAL C 3 15  ? 87.664  134.595 166.954 1.00 170.70 ? 15  VAL L C   1 
ATOM   7204  O O   . VAL C 3 15  ? 86.684  135.154 167.454 1.00 207.97 ? 15  VAL L O   1 
ATOM   7205  C CB  . VAL C 3 15  ? 89.742  136.016 167.255 1.00 193.09 ? 15  VAL L CB  1 
ATOM   7206  C CG1 . VAL C 3 15  ? 90.302  134.960 168.218 1.00 164.47 ? 15  VAL L CG1 1 
ATOM   7207  C CG2 . VAL C 3 15  ? 90.860  136.761 166.534 1.00 245.01 ? 15  VAL L CG2 1 
ATOM   7208  N N   . GLY C 3 16  ? 87.863  133.265 166.982 1.00 157.52 ? 16  GLY L N   1 
ATOM   7209  C CA  . GLY C 3 16  ? 86.903  132.330 167.550 1.00 192.22 ? 16  GLY L CA  1 
ATOM   7210  C C   . GLY C 3 16  ? 85.894  131.737 166.558 1.00 170.44 ? 16  GLY L C   1 
ATOM   7211  O O   . GLY C 3 16  ? 85.339  130.679 166.853 1.00 206.81 ? 16  GLY L O   1 
ATOM   7212  N N   . GLN C 3 17  ? 85.647  132.386 165.407 1.00 169.17 ? 17  GLN L N   1 
ATOM   7213  C CA  . GLN C 3 17  ? 84.612  131.964 164.464 1.00 200.63 ? 17  GLN L CA  1 
ATOM   7214  C C   . GLN C 3 17  ? 85.099  130.831 163.544 1.00 193.53 ? 17  GLN L C   1 
ATOM   7215  O O   . GLN C 3 17  ? 86.297  130.626 163.356 1.00 186.84 ? 17  GLN L O   1 
ATOM   7216  C CB  . GLN C 3 17  ? 84.148  133.157 163.618 1.00 187.56 ? 17  GLN L CB  1 
ATOM   7217  C CG  . GLN C 3 17  ? 83.576  134.306 164.438 1.00 247.80 ? 17  GLN L CG  1 
ATOM   7218  C CD  . GLN C 3 17  ? 82.332  133.962 165.223 1.00 362.13 ? 17  GLN L CD  1 
ATOM   7219  O OE1 . GLN C 3 17  ? 81.622  133.005 164.917 1.00 421.68 ? 17  GLN L OE1 1 
ATOM   7220  N NE2 . GLN C 3 17  ? 82.049  134.752 166.250 1.00 411.23 ? 17  GLN L NE2 1 
ATOM   7221  N N   . LYS C 3 18  ? 84.135  130.108 162.954 1.00 170.28 ? 18  LYS L N   1 
ATOM   7222  C CA  . LYS C 3 18  ? 84.378  129.075 161.956 1.00 171.13 ? 18  LYS L CA  1 
ATOM   7223  C C   . LYS C 3 18  ? 84.492  129.683 160.560 1.00 173.14 ? 18  LYS L C   1 
ATOM   7224  O O   . LYS C 3 18  ? 83.727  130.600 160.253 1.00 182.90 ? 18  LYS L O   1 
ATOM   7225  C CB  . LYS C 3 18  ? 83.208  128.085 161.958 1.00 227.63 ? 18  LYS L CB  1 
ATOM   7226  C CG  . LYS C 3 18  ? 83.246  126.966 160.925 1.00 242.47 ? 18  LYS L CG  1 
ATOM   7227  C CD  . LYS C 3 18  ? 82.041  126.065 161.047 1.00 231.87 ? 18  LYS L CD  1 
ATOM   7228  C CE  . LYS C 3 18  ? 81.987  124.979 159.997 1.00 247.08 ? 18  LYS L CE  1 
ATOM   7229  N NZ  . LYS C 3 18  ? 81.107  123.860 160.411 1.00 279.32 ? 18  LYS L NZ  1 
ATOM   7230  N N   . VAL C 3 19  ? 85.431  129.161 159.723 1.00 167.16 ? 19  VAL L N   1 
ATOM   7231  C CA  . VAL C 3 19  ? 85.680  129.662 158.364 1.00 178.32 ? 19  VAL L CA  1 
ATOM   7232  C C   . VAL C 3 19  ? 85.877  128.525 157.362 1.00 167.43 ? 19  VAL L C   1 
ATOM   7233  O O   . VAL C 3 19  ? 86.279  127.425 157.752 1.00 153.64 ? 19  VAL L O   1 
ATOM   7234  C CB  . VAL C 3 19  ? 86.895  130.607 158.296 1.00 169.54 ? 19  VAL L CB  1 
ATOM   7235  C CG1 . VAL C 3 19  ? 86.814  131.690 159.342 1.00 241.12 ? 19  VAL L CG1 1 
ATOM   7236  C CG2 . VAL C 3 19  ? 88.215  129.895 158.434 1.00 169.79 ? 19  VAL L CG2 1 
ATOM   7237  N N   . THR C 3 20  ? 85.605  128.840 156.082 1.00 145.03 ? 20  THR L N   1 
ATOM   7238  C CA  . THR C 3 20  ? 85.573  127.863 155.002 1.00 139.31 ? 20  THR L CA  1 
ATOM   7239  C C   . THR C 3 20  ? 86.241  128.438 153.748 1.00 163.13 ? 20  THR L C   1 
ATOM   7240  O O   . THR C 3 20  ? 85.872  129.533 153.303 1.00 159.97 ? 20  THR L O   1 
ATOM   7241  C CB  . THR C 3 20  ? 84.130  127.455 154.689 1.00 193.52 ? 20  THR L CB  1 
ATOM   7242  O OG1 . THR C 3 20  ? 83.549  126.825 155.834 1.00 195.06 ? 20  THR L OG1 1 
ATOM   7243  C CG2 . THR C 3 20  ? 83.997  126.499 153.523 1.00 245.50 ? 20  THR L CG2 1 
ATOM   7244  N N   . MET C 3 21  ? 87.207  127.672 153.201 1.00 136.28 ? 21  MET L N   1 
ATOM   7245  C CA  . MET C 3 21  ? 87.809  127.890 151.888 1.00 116.12 ? 21  MET L CA  1 
ATOM   7246  C C   . MET C 3 21  ? 87.154  126.890 150.928 1.00 115.40 ? 21  MET L C   1 
ATOM   7247  O O   . MET C 3 21  ? 86.879  125.755 151.307 1.00 129.80 ? 21  MET L O   1 
ATOM   7248  C CB  . MET C 3 21  ? 89.308  127.628 151.856 1.00 107.75 ? 21  MET L CB  1 
ATOM   7249  C CG  . MET C 3 21  ? 90.055  127.781 153.174 1.00 145.91 ? 21  MET L CG  1 
ATOM   7250  S SD  . MET C 3 21  ? 90.416  129.437 153.534 1.00 148.02 ? 21  MET L SD  1 
ATOM   7251  C CE  . MET C 3 21  ? 91.382  129.240 155.050 1.00 114.25 ? 21  MET L CE  1 
ATOM   7252  N N   . ASN C 3 22  ? 86.901  127.284 149.684 1.00 100.65 ? 22  ASN L N   1 
ATOM   7253  C CA  . ASN C 3 22  ? 86.482  126.357 148.646 1.00 125.81 ? 22  ASN L CA  1 
ATOM   7254  C C   . ASN C 3 22  ? 87.581  126.216 147.588 1.00 125.53 ? 22  ASN L C   1 
ATOM   7255  O O   . ASN C 3 22  ? 88.204  127.205 147.175 1.00 145.04 ? 22  ASN L O   1 
ATOM   7256  C CB  . ASN C 3 22  ? 85.190  126.818 147.964 1.00 209.71 ? 22  ASN L CB  1 
ATOM   7257  C CG  . ASN C 3 22  ? 83.993  126.694 148.870 1.00 205.76 ? 22  ASN L CG  1 
ATOM   7258  O OD1 . ASN C 3 22  ? 83.442  125.601 148.929 1.00 196.94 ? 22  ASN L OD1 1 
ATOM   7259  N ND2 . ASN C 3 22  ? 83.606  127.766 149.557 1.00 211.81 ? 22  ASN L ND2 1 
ATOM   7260  N N   . CYS C 3 23  ? 87.766  124.966 147.147 1.00 96.42  ? 23  CYS L N   1 
ATOM   7261  C CA  . CYS C 3 23  ? 88.637  124.620 146.045 1.00 108.78 ? 23  CYS L CA  1 
ATOM   7262  C C   . CYS C 3 23  ? 87.854  123.804 145.036 1.00 103.14 ? 23  CYS L C   1 
ATOM   7263  O O   . CYS C 3 23  ? 87.065  122.963 145.436 1.00 143.52 ? 23  CYS L O   1 
ATOM   7264  C CB  . CYS C 3 23  ? 89.828  123.818 146.546 1.00 113.51 ? 23  CYS L CB  1 
ATOM   7265  S SG  . CYS C 3 23  ? 91.010  123.397 145.218 1.00 198.30 ? 23  CYS L SG  1 
ATOM   7266  N N   . LYS C 3 24  ? 88.069  124.060 143.744 1.00 97.41  ? 24  LYS L N   1 
ATOM   7267  C CA  . LYS C 3 24  ? 87.183  123.571 142.703 1.00 124.39 ? 24  LYS L CA  1 
ATOM   7268  C C   . LYS C 3 24  ? 88.033  123.178 141.505 1.00 108.64 ? 24  LYS L C   1 
ATOM   7269  O O   . LYS C 3 24  ? 88.595  124.057 140.846 1.00 150.70 ? 24  LYS L O   1 
ATOM   7270  C CB  . LYS C 3 24  ? 86.147  124.657 142.358 1.00 216.07 ? 24  LYS L CB  1 
ATOM   7271  C CG  . LYS C 3 24  ? 85.146  124.346 141.251 1.00 225.10 ? 24  LYS L CG  1 
ATOM   7272  C CD  . LYS C 3 24  ? 84.271  123.178 141.553 1.00 238.17 ? 24  LYS L CD  1 
ATOM   7273  C CE  . LYS C 3 24  ? 83.126  123.007 140.578 1.00 295.29 ? 24  LYS L CE  1 
ATOM   7274  N NZ  . LYS C 3 24  ? 82.264  121.863 140.960 1.00 357.14 ? 24  LYS L NZ  1 
ATOM   7275  N N   . SER C 3 25  ? 88.088  121.860 141.232 1.00 105.47 ? 25  SER L N   1 
ATOM   7276  C CA  . SER C 3 25  ? 88.988  121.276 140.237 1.00 115.18 ? 25  SER L CA  1 
ATOM   7277  C C   . SER C 3 25  ? 88.324  121.006 138.874 1.00 100.97 ? 25  SER L C   1 
ATOM   7278  O O   . SER C 3 25  ? 87.208  120.496 138.798 1.00 119.17 ? 25  SER L O   1 
ATOM   7279  C CB  . SER C 3 25  ? 89.553  120.024 140.789 1.00 124.82 ? 25  SER L CB  1 
ATOM   7280  O OG  . SER C 3 25  ? 88.487  119.145 141.101 1.00 145.69 ? 25  SER L OG  1 
ATOM   7281  N N   . SER C 3 26  ? 89.033  121.338 137.793 1.00 101.84 ? 26  SER L N   1 
ATOM   7282  C CA  . SER C 3 26  ? 88.566  121.126 136.427 1.00 147.24 ? 26  SER L CA  1 
ATOM   7283  C C   . SER C 3 26  ? 88.498  119.648 135.994 1.00 140.54 ? 26  SER L C   1 
ATOM   7284  O O   . SER C 3 26  ? 88.193  119.356 134.840 1.00 198.71 ? 26  SER L O   1 
ATOM   7285  C CB  . SER C 3 26  ? 89.448  121.923 135.457 1.00 208.05 ? 26  SER L CB  1 
ATOM   7286  O OG  . SER C 3 26  ? 90.707  121.293 135.216 1.00 203.48 ? 26  SER L OG  1 
ATOM   7287  N N   . GLN C 3 27  ? 88.824  118.706 136.881 1.00 126.61 ? 27  GLN L N   1 
ATOM   7288  C CA  . GLN C 3 27  ? 88.546  117.292 136.710 1.00 132.18 ? 27  GLN L CA  1 
ATOM   7289  C C   . GLN C 3 27  ? 88.305  116.692 138.077 1.00 118.62 ? 27  GLN L C   1 
ATOM   7290  O O   . GLN C 3 27  ? 88.611  117.301 139.088 1.00 117.02 ? 27  GLN L O   1 
ATOM   7291  C CB  . GLN C 3 27  ? 89.730  116.490 136.172 1.00 148.80 ? 27  GLN L CB  1 
ATOM   7292  C CG  . GLN C 3 27  ? 90.148  116.806 134.752 1.00 205.58 ? 27  GLN L CG  1 
ATOM   7293  C CD  . GLN C 3 27  ? 91.266  115.866 134.345 1.00 250.47 ? 27  GLN L CD  1 
ATOM   7294  O OE1 . GLN C 3 27  ? 92.080  116.209 133.490 1.00 290.30 ? 27  GLN L OE1 1 
ATOM   7295  N NE2 . GLN C 3 27  ? 91.339  114.688 134.966 1.00 184.82 ? 27  GLN L NE2 1 
ATOM   7296  N N   . SER C 3 28  ? 87.760  115.487 138.095 1.00 132.54 ? 28  SER L N   1 
ATOM   7297  C CA  . SER C 3 28  ? 87.614  114.747 139.331 1.00 121.88 ? 28  SER L CA  1 
ATOM   7298  C C   . SER C 3 28  ? 88.990  114.298 139.815 1.00 109.10 ? 28  SER L C   1 
ATOM   7299  O O   . SER C 3 28  ? 89.877  113.945 139.034 1.00 137.86 ? 28  SER L O   1 
ATOM   7300  C CB  . SER C 3 28  ? 86.712  113.569 139.106 1.00 212.58 ? 28  SER L CB  1 
ATOM   7301  O OG  . SER C 3 28  ? 86.582  112.795 140.277 1.00 199.32 ? 28  SER L OG  1 
ATOM   7302  N N   . LEU C 3 29  ? 89.158  114.314 141.123 1.00 94.67  ? 29  LEU L N   1 
ATOM   7303  C CA  . LEU C 3 29  ? 90.372  113.843 141.775 1.00 95.32  ? 29  LEU L CA  1 
ATOM   7304  C C   . LEU C 3 29  ? 90.004  112.711 142.710 1.00 122.15 ? 29  LEU L C   1 
ATOM   7305  O O   . LEU C 3 29  ? 90.687  112.543 143.711 1.00 93.02  ? 29  LEU L O   1 
ATOM   7306  C CB  . LEU C 3 29  ? 91.005  114.950 142.644 1.00 73.91  ? 29  LEU L CB  1 
ATOM   7307  C CG  . LEU C 3 29  ? 91.017  116.346 142.052 1.00 83.92  ? 29  LEU L CG  1 
ATOM   7308  C CD1 . LEU C 3 29  ? 91.490  117.347 143.110 1.00 85.87  ? 29  LEU L CD1 1 
ATOM   7309  C CD2 . LEU C 3 29  ? 91.855  116.426 140.757 1.00 82.87  ? 29  LEU L CD2 1 
ATOM   7310  N N   . LEU C 3 30  ? 88.930  111.974 142.408 1.00 127.05 ? 30  LEU L N   1 
ATOM   7311  C CA  . LEU C 3 30  ? 88.678  110.687 143.029 1.00 127.61 ? 30  LEU L CA  1 
ATOM   7312  C C   . LEU C 3 30  ? 89.356  109.630 142.157 1.00 134.76 ? 30  LEU L C   1 
ATOM   7313  O O   . LEU C 3 30  ? 89.130  109.546 140.929 1.00 109.32 ? 30  LEU L O   1 
ATOM   7314  C CB  . LEU C 3 30  ? 87.163  110.474 143.106 1.00 150.60 ? 30  LEU L CB  1 
ATOM   7315  C CG  . LEU C 3 30  ? 86.707  109.104 143.567 1.00 159.16 ? 30  LEU L CG  1 
ATOM   7316  C CD1 . LEU C 3 30  ? 87.273  108.861 144.946 1.00 105.72 ? 30  LEU L CD1 1 
ATOM   7317  C CD2 . LEU C 3 30  ? 85.183  108.998 143.523 1.00 233.90 ? 30  LEU L CD2 1 
ATOM   7318  N N   . ASN C 3 31  ? 90.194  108.804 142.813 1.00 139.50 ? 31  ASN L N   1 
ATOM   7319  C CA  . ASN C 3 31  ? 90.786  107.625 142.190 1.00 146.35 ? 31  ASN L CA  1 
ATOM   7320  C C   . ASN C 3 31  ? 89.832  106.459 142.419 1.00 150.67 ? 31  ASN L C   1 
ATOM   7321  O O   . ASN C 3 31  ? 89.765  105.914 143.520 1.00 158.86 ? 31  ASN L O   1 
ATOM   7322  C CB  . ASN C 3 31  ? 92.196  107.398 142.720 1.00 156.77 ? 31  ASN L CB  1 
ATOM   7323  C CG  . ASN C 3 31  ? 92.865  106.120 142.277 1.00 159.95 ? 31  ASN L CG  1 
ATOM   7324  O OD1 . ASN C 3 31  ? 92.477  105.440 141.314 1.00 216.57 ? 31  ASN L OD1 1 
ATOM   7325  N ND2 . ASN C 3 31  ? 93.881  105.758 143.044 1.00 201.18 ? 31  ASN L ND2 1 
ATOM   7326  N N   . ASN C 3 32  ? 89.097  106.086 141.356 1.00 171.18 ? 32  ASN L N   1 
ATOM   7327  C CA  . ASN C 3 32  ? 88.037  105.078 141.373 1.00 169.60 ? 32  ASN L CA  1 
ATOM   7328  C C   . ASN C 3 32  ? 88.472  103.771 142.043 1.00 159.65 ? 32  ASN L C   1 
ATOM   7329  O O   . ASN C 3 32  ? 87.723  103.194 142.822 1.00 142.82 ? 32  ASN L O   1 
ATOM   7330  C CB  . ASN C 3 32  ? 87.569  104.764 139.949 1.00 181.69 ? 32  ASN L CB  1 
ATOM   7331  C CG  . ASN C 3 32  ? 87.073  105.989 139.209 1.00 236.44 ? 32  ASN L CG  1 
ATOM   7332  O OD1 . ASN C 3 32  ? 86.251  106.738 139.739 1.00 268.74 ? 32  ASN L OD1 1 
ATOM   7333  N ND2 . ASN C 3 32  ? 87.555  106.205 137.990 1.00 278.99 ? 32  ASN L ND2 1 
ATOM   7334  N N   . ASN C 3 33  ? 89.697  103.324 141.727 1.00 196.58 ? 33  ASN L N   1 
ATOM   7335  C CA  . ASN C 3 33  ? 90.244  102.041 142.155 1.00 160.18 ? 33  ASN L CA  1 
ATOM   7336  C C   . ASN C 3 33  ? 90.441  101.986 143.677 1.00 158.34 ? 33  ASN L C   1 
ATOM   7337  O O   . ASN C 3 33  ? 90.581  100.895 144.221 1.00 150.73 ? 33  ASN L O   1 
ATOM   7338  C CB  . ASN C 3 33  ? 91.596  101.733 141.488 1.00 181.93 ? 33  ASN L CB  1 
ATOM   7339  C CG  . ASN C 3 33  ? 91.621  101.986 139.994 1.00 245.88 ? 33  ASN L CG  1 
ATOM   7340  O OD1 . ASN C 3 33  ? 90.981  101.264 139.228 1.00 233.48 ? 33  ASN L OD1 1 
ATOM   7341  N ND2 . ASN C 3 33  ? 92.351  103.012 139.575 1.00 282.14 ? 33  ASN L ND2 1 
ATOM   7342  N N   . ASN C 3 34  ? 90.474  103.154 144.358 1.00 140.60 ? 34  ASN L N   1 
ATOM   7343  C CA  . ASN C 3 34  ? 91.020  103.258 145.712 1.00 176.41 ? 34  ASN L CA  1 
ATOM   7344  C C   . ASN C 3 34  ? 90.130  104.063 146.658 1.00 189.98 ? 34  ASN L C   1 
ATOM   7345  O O   . ASN C 3 34  ? 90.350  103.957 147.870 1.00 176.15 ? 34  ASN L O   1 
ATOM   7346  C CB  . ASN C 3 34  ? 92.454  103.806 145.687 1.00 145.60 ? 34  ASN L CB  1 
ATOM   7347  C CG  . ASN C 3 34  ? 93.212  103.524 146.959 1.00 254.19 ? 34  ASN L CG  1 
ATOM   7348  O OD1 . ASN C 3 34  ? 93.702  104.427 147.639 1.00 353.63 ? 34  ASN L OD1 1 
ATOM   7349  N ND2 . ASN C 3 34  ? 93.308  102.252 147.308 1.00 331.52 ? 34  ASN L ND2 1 
ATOM   7350  N N   . GLN C 3 35  ? 89.159  104.835 146.130 1.00 192.48 ? 35  GLN L N   1 
ATOM   7351  C CA  . GLN C 3 35  ? 88.158  105.514 146.932 1.00 165.94 ? 35  GLN L CA  1 
ATOM   7352  C C   . GLN C 3 35  ? 88.857  106.460 147.898 1.00 156.39 ? 35  GLN L C   1 
ATOM   7353  O O   . GLN C 3 35  ? 88.491  106.523 149.085 1.00 250.74 ? 35  GLN L O   1 
ATOM   7354  C CB  . GLN C 3 35  ? 87.209  104.526 147.609 1.00 233.25 ? 35  GLN L CB  1 
ATOM   7355  C CG  . GLN C 3 35  ? 86.415  103.692 146.619 1.00 278.46 ? 35  GLN L CG  1 
ATOM   7356  C CD  . GLN C 3 35  ? 85.507  104.519 145.726 1.00 278.24 ? 35  GLN L CD  1 
ATOM   7357  O OE1 . GLN C 3 35  ? 84.795  105.418 146.180 1.00 278.39 ? 35  GLN L OE1 1 
ATOM   7358  N NE2 . GLN C 3 35  ? 85.518  104.225 144.432 1.00 223.33 ? 35  GLN L NE2 1 
ATOM   7359  N N   . LYS C 3 36  ? 89.836  107.228 147.362 1.00 133.49 ? 36  LYS L N   1 
ATOM   7360  C CA  . LYS C 3 36  ? 90.206  108.473 148.018 1.00 164.96 ? 36  LYS L CA  1 
ATOM   7361  C C   . LYS C 3 36  ? 90.557  109.536 147.002 1.00 135.47 ? 36  LYS L C   1 
ATOM   7362  O O   . LYS C 3 36  ? 90.817  109.253 145.827 1.00 90.11  ? 36  LYS L O   1 
ATOM   7363  C CB  . LYS C 3 36  ? 91.318  108.315 149.048 1.00 151.97 ? 36  LYS L CB  1 
ATOM   7364  C CG  . LYS C 3 36  ? 92.659  107.920 148.516 1.00 129.48 ? 36  LYS L CG  1 
ATOM   7365  C CD  . LYS C 3 36  ? 93.491  107.238 149.605 1.00 165.98 ? 36  LYS L CD  1 
ATOM   7366  C CE  . LYS C 3 36  ? 94.857  106.869 149.109 1.00 212.74 ? 36  LYS L CE  1 
ATOM   7367  N NZ  . LYS C 3 36  ? 95.383  105.707 149.862 1.00 241.21 ? 36  LYS L NZ  1 
ATOM   7368  N N   . ASN C 3 37  ? 90.503  110.762 147.551 1.00 126.21 ? 37  ASN L N   1 
ATOM   7369  C CA  . ASN C 3 37  ? 90.468  111.970 146.771 1.00 105.64 ? 37  ASN L CA  1 
ATOM   7370  C C   . ASN C 3 37  ? 91.788  112.671 146.980 1.00 103.88 ? 37  ASN L C   1 
ATOM   7371  O O   . ASN C 3 37  ? 92.200  112.922 148.116 1.00 94.83  ? 37  ASN L O   1 
ATOM   7372  C CB  . ASN C 3 37  ? 89.336  112.869 147.200 1.00 114.08 ? 37  ASN L CB  1 
ATOM   7373  C CG  . ASN C 3 37  ? 87.961  112.362 146.869 1.00 162.91 ? 37  ASN L CG  1 
ATOM   7374  O OD1 . ASN C 3 37  ? 87.456  112.695 145.795 1.00 132.81 ? 37  ASN L OD1 1 
ATOM   7375  N ND2 . ASN C 3 37  ? 87.361  111.601 147.781 1.00 187.01 ? 37  ASN L ND2 1 
ATOM   7376  N N   . TYR C 3 38  ? 92.457  112.978 145.875 1.00 85.84  ? 38  TYR L N   1 
ATOM   7377  C CA  . TYR C 3 38  ? 93.808  113.520 145.941 1.00 79.09  ? 38  TYR L CA  1 
ATOM   7378  C C   . TYR C 3 38  ? 93.772  115.021 145.999 1.00 68.53  ? 38  TYR L C   1 
ATOM   7379  O O   . TYR C 3 38  ? 93.594  115.630 144.987 1.00 92.10  ? 38  TYR L O   1 
ATOM   7380  C CB  . TYR C 3 38  ? 94.514  112.946 144.726 1.00 77.65  ? 38  TYR L CB  1 
ATOM   7381  C CG  . TYR C 3 38  ? 94.825  111.450 144.760 1.00 84.77  ? 38  TYR L CG  1 
ATOM   7382  C CD1 . TYR C 3 38  ? 94.751  110.687 145.913 1.00 110.11 ? 38  TYR L CD1 1 
ATOM   7383  C CD2 . TYR C 3 38  ? 95.227  110.789 143.642 1.00 78.89  ? 38  TYR L CD2 1 
ATOM   7384  C CE1 . TYR C 3 38  ? 95.049  109.329 145.946 1.00 123.94 ? 38  TYR L CE1 1 
ATOM   7385  C CE2 . TYR C 3 38  ? 95.528  109.447 143.645 1.00 87.24  ? 38  TYR L CE2 1 
ATOM   7386  C CZ  . TYR C 3 38  ? 95.448  108.703 144.794 1.00 111.02 ? 38  TYR L CZ  1 
ATOM   7387  O OH  . TYR C 3 38  ? 95.737  107.364 144.787 1.00 195.59 ? 38  TYR L OH  1 
ATOM   7388  N N   . LEU C 3 39  ? 93.879  115.596 147.187 1.00 68.59  ? 39  LEU L N   1 
ATOM   7389  C CA  . LEU C 3 39  ? 94.011  117.032 147.351 1.00 71.96  ? 39  LEU L CA  1 
ATOM   7390  C C   . LEU C 3 39  ? 94.742  117.364 148.637 1.00 80.28  ? 39  LEU L C   1 
ATOM   7391  O O   . LEU C 3 39  ? 94.662  116.590 149.585 1.00 106.14 ? 39  LEU L O   1 
ATOM   7392  C CB  . LEU C 3 39  ? 92.646  117.653 147.532 1.00 58.99  ? 39  LEU L CB  1 
ATOM   7393  C CG  . LEU C 3 39  ? 92.648  119.117 147.263 1.00 76.37  ? 39  LEU L CG  1 
ATOM   7394  C CD1 . LEU C 3 39  ? 92.599  119.332 145.709 1.00 87.80  ? 39  LEU L CD1 1 
ATOM   7395  C CD2 . LEU C 3 39  ? 91.553  119.730 148.103 1.00 110.70 ? 39  LEU L CD2 1 
ATOM   7396  N N   . ALA C 3 40  ? 95.413  118.510 148.650 1.00 59.62  ? 40  ALA L N   1 
ATOM   7397  C CA  . ALA C 3 40  ? 96.073  119.007 149.820 1.00 52.04  ? 40  ALA L CA  1 
ATOM   7398  C C   . ALA C 3 40  ? 95.904  120.510 149.949 1.00 65.02  ? 40  ALA L C   1 
ATOM   7399  O O   . ALA C 3 40  ? 95.683  121.180 148.972 1.00 76.61  ? 40  ALA L O   1 
ATOM   7400  C CB  . ALA C 3 40  ? 97.530  118.716 149.661 1.00 65.87  ? 40  ALA L CB  1 
ATOM   7401  N N   . TRP C 3 41  ? 96.090  120.968 151.176 1.00 66.52  ? 41  TRP L N   1 
ATOM   7402  C CA  . TRP C 3 41  ? 96.003  122.327 151.621 1.00 62.15  ? 41  TRP L CA  1 
ATOM   7403  C C   . TRP C 3 41  ? 97.333  122.751 152.247 1.00 58.67  ? 41  TRP L C   1 
ATOM   7404  O O   . TRP C 3 41  ? 97.827  122.117 153.158 1.00 77.54  ? 41  TRP L O   1 
ATOM   7405  C CB  . TRP C 3 41  ? 94.832  122.415 152.648 1.00 82.19  ? 41  TRP L CB  1 
ATOM   7406  C CG  . TRP C 3 41  ? 93.505  122.406 151.946 1.00 70.21  ? 41  TRP L CG  1 
ATOM   7407  C CD1 . TRP C 3 41  ? 92.743  121.325 151.782 1.00 77.51  ? 41  TRP L CD1 1 
ATOM   7408  C CD2 . TRP C 3 41  ? 92.835  123.473 151.262 1.00 70.58  ? 41  TRP L CD2 1 
ATOM   7409  N NE1 . TRP C 3 41  ? 91.649  121.624 151.055 1.00 93.07  ? 41  TRP L NE1 1 
ATOM   7410  C CE2 . TRP C 3 41  ? 91.690  122.945 150.727 1.00 77.05  ? 41  TRP L CE2 1 
ATOM   7411  C CE3 . TRP C 3 41  ? 93.099  124.820 151.045 1.00 107.40 ? 41  TRP L CE3 1 
ATOM   7412  C CZ2 . TRP C 3 41  ? 90.797  123.700 150.001 1.00 86.75  ? 41  TRP L CZ2 1 
ATOM   7413  C CZ3 . TRP C 3 41  ? 92.216  125.579 150.330 1.00 122.04 ? 41  TRP L CZ3 1 
ATOM   7414  C CH2 . TRP C 3 41  ? 91.073  125.016 149.809 1.00 115.54 ? 41  TRP L CH2 1 
ATOM   7415  N N   . TYR C 3 42  ? 97.908  123.875 151.823 1.00 65.04  ? 42  TYR L N   1 
ATOM   7416  C CA  . TYR C 3 42  ? 99.087  124.426 152.470 1.00 63.54  ? 42  TYR L CA  1 
ATOM   7417  C C   . TYR C 3 42  ? 98.769  125.798 152.994 1.00 56.93  ? 42  TYR L C   1 
ATOM   7418  O O   . TYR C 3 42  ? 98.110  126.542 152.318 1.00 58.09  ? 42  TYR L O   1 
ATOM   7419  C CB  . TYR C 3 42  ? 100.252 124.645 151.519 1.00 62.24  ? 42  TYR L CB  1 
ATOM   7420  C CG  . TYR C 3 42  ? 100.689 123.360 150.810 1.00 62.52  ? 42  TYR L CG  1 
ATOM   7421  C CD1 . TYR C 3 42  ? 100.105 122.905 149.675 1.00 59.09  ? 42  TYR L CD1 1 
ATOM   7422  C CD2 . TYR C 3 42  ? 101.713 122.592 151.294 1.00 64.71  ? 42  TYR L CD2 1 
ATOM   7423  C CE1 . TYR C 3 42  ? 100.480 121.740 149.051 1.00 67.86  ? 42  TYR L CE1 1 
ATOM   7424  C CE2 . TYR C 3 42  ? 102.125 121.438 150.678 1.00 69.41  ? 42  TYR L CE2 1 
ATOM   7425  C CZ  . TYR C 3 42  ? 101.504 120.994 149.539 1.00 66.28  ? 42  TYR L CZ  1 
ATOM   7426  O OH  . TYR C 3 42  ? 101.891 119.828 148.940 1.00 74.84  ? 42  TYR L OH  1 
ATOM   7427  N N   . GLN C 3 43  ? 99.265  126.074 154.186 1.00 72.68  ? 43  GLN L N   1 
ATOM   7428  C CA  . GLN C 3 43  ? 99.232  127.377 154.826 1.00 77.59  ? 43  GLN L CA  1 
ATOM   7429  C C   . GLN C 3 43  ? 100.573 128.045 154.557 1.00 63.58  ? 43  GLN L C   1 
ATOM   7430  O O   . GLN C 3 43  ? 101.609 127.442 154.723 1.00 100.56 ? 43  GLN L O   1 
ATOM   7431  C CB  . GLN C 3 43  ? 99.020  127.186 156.333 1.00 89.63  ? 43  GLN L CB  1 
ATOM   7432  C CG  . GLN C 3 43  ? 99.119  128.451 157.147 1.00 106.17 ? 43  GLN L CG  1 
ATOM   7433  C CD  . GLN C 3 43  ? 99.039  128.332 158.646 1.00 122.87 ? 43  GLN L CD  1 
ATOM   7434  O OE1 . GLN C 3 43  ? 99.179  129.305 159.370 1.00 242.19 ? 43  GLN L OE1 1 
ATOM   7435  N NE2 . GLN C 3 43  ? 98.846  127.162 159.171 1.00 132.52 ? 43  GLN L NE2 1 
ATOM   7436  N N   . GLN C 3 44  ? 100.587 129.300 154.155 1.00 64.05  ? 44  GLN L N   1 
ATOM   7437  C CA  . GLN C 3 44  ? 101.839 130.036 154.026 1.00 73.14  ? 44  GLN L CA  1 
ATOM   7438  C C   . GLN C 3 44  ? 101.660 131.377 154.732 1.00 72.16  ? 44  GLN L C   1 
ATOM   7439  O O   . GLN C 3 44  ? 100.968 132.324 154.239 1.00 71.23  ? 44  GLN L O   1 
ATOM   7440  C CB  . GLN C 3 44  ? 102.252 130.170 152.560 1.00 82.64  ? 44  GLN L CB  1 
ATOM   7441  C CG  . GLN C 3 44  ? 103.447 131.017 152.388 1.00 89.69  ? 44  GLN L CG  1 
ATOM   7442  C CD  . GLN C 3 44  ? 103.898 131.073 150.965 1.00 126.08 ? 44  GLN L CD  1 
ATOM   7443  O OE1 . GLN C 3 44  ? 103.105 131.074 150.026 1.00 144.51 ? 44  GLN L OE1 1 
ATOM   7444  N NE2 . GLN C 3 44  ? 105.208 131.167 150.822 1.00 201.24 ? 44  GLN L NE2 1 
ATOM   7445  N N   . LYS C 3 45  ? 102.290 131.395 155.915 1.00 69.21  ? 45  LYS L N   1 
ATOM   7446  C CA  . LYS C 3 45  ? 102.254 132.582 156.737 1.00 99.69  ? 45  LYS L CA  1 
ATOM   7447  C C   . LYS C 3 45  ? 103.121 133.630 156.052 1.00 95.88  ? 45  LYS L C   1 
ATOM   7448  O O   . LYS C 3 45  ? 104.027 133.283 155.276 1.00 128.26 ? 45  LYS L O   1 
ATOM   7449  C CB  . LYS C 3 45  ? 102.722 132.240 158.152 1.00 149.61 ? 45  LYS L CB  1 
ATOM   7450  C CG  . LYS C 3 45  ? 101.711 131.550 159.057 1.00 155.17 ? 45  LYS L CG  1 
ATOM   7451  C CD  . LYS C 3 45  ? 102.201 131.520 160.507 1.00 196.96 ? 45  LYS L CD  1 
ATOM   7452  C CE  . LYS C 3 45  ? 101.862 130.261 161.281 1.00 250.58 ? 45  LYS L CE  1 
ATOM   7453  N NZ  . LYS C 3 45  ? 100.417 130.169 161.625 1.00 323.69 ? 45  LYS L NZ  1 
ATOM   7454  N N   . PRO C 3 46  ? 102.904 134.929 156.333 1.00 119.84 ? 46  PRO L N   1 
ATOM   7455  C CA  . PRO C 3 46  ? 103.680 135.962 155.669 1.00 156.63 ? 46  PRO L CA  1 
ATOM   7456  C C   . PRO C 3 46  ? 105.138 135.775 156.114 1.00 168.43 ? 46  PRO L C   1 
ATOM   7457  O O   . PRO C 3 46  ? 105.435 135.648 157.324 1.00 137.85 ? 46  PRO L O   1 
ATOM   7458  C CB  . PRO C 3 46  ? 103.010 137.266 156.136 1.00 198.79 ? 46  PRO L CB  1 
ATOM   7459  C CG  . PRO C 3 46  ? 102.472 136.873 157.506 1.00 205.64 ? 46  PRO L CG  1 
ATOM   7460  C CD  . PRO C 3 46  ? 101.940 135.472 157.298 1.00 165.15 ? 46  PRO L CD  1 
ATOM   7461  N N   . GLY C 3 47  ? 106.028 135.749 155.099 1.00 170.73 ? 47  GLY L N   1 
ATOM   7462  C CA  . GLY C 3 47  ? 107.466 135.715 155.289 1.00 196.62 ? 47  GLY L CA  1 
ATOM   7463  C C   . GLY C 3 47  ? 108.055 134.331 155.558 1.00 149.95 ? 47  GLY L C   1 
ATOM   7464  O O   . GLY C 3 47  ? 109.190 134.262 156.026 1.00 218.09 ? 47  GLY L O   1 
ATOM   7465  N N   . GLN C 3 48  ? 107.317 133.253 155.257 1.00 142.58 ? 48  GLN L N   1 
ATOM   7466  C CA  . GLN C 3 48  ? 107.771 131.877 155.481 1.00 131.96 ? 48  GLN L CA  1 
ATOM   7467  C C   . GLN C 3 48  ? 107.397 130.959 154.301 1.00 103.23 ? 48  GLN L C   1 
ATOM   7468  O O   . GLN C 3 48  ? 106.770 131.353 153.321 1.00 175.42 ? 48  GLN L O   1 
ATOM   7469  C CB  . GLN C 3 48  ? 107.176 131.295 156.774 1.00 123.06 ? 48  GLN L CB  1 
ATOM   7470  C CG  . GLN C 3 48  ? 107.470 132.083 158.037 1.00 143.93 ? 48  GLN L CG  1 
ATOM   7471  C CD  . GLN C 3 48  ? 106.718 131.534 159.231 1.00 218.44 ? 48  GLN L CD  1 
ATOM   7472  O OE1 . GLN C 3 48  ? 106.178 130.428 159.207 1.00 185.83 ? 48  GLN L OE1 1 
ATOM   7473  N NE2 . GLN C 3 48  ? 106.680 132.310 160.307 1.00 301.49 ? 48  GLN L NE2 1 
ATOM   7474  N N   . SER C 3 49  ? 107.795 129.696 154.433 1.00 114.02 ? 49  SER L N   1 
ATOM   7475  C CA  . SER C 3 49  ? 107.630 128.648 153.442 1.00 100.15 ? 49  SER L CA  1 
ATOM   7476  C C   . SER C 3 49  ? 106.253 128.104 153.517 1.00 77.63  ? 49  SER L C   1 
ATOM   7477  O O   . SER C 3 49  ? 105.622 128.257 154.547 1.00 123.97 ? 49  SER L O   1 
ATOM   7478  C CB  . SER C 3 49  ? 108.609 127.498 153.692 1.00 154.13 ? 49  SER L CB  1 
ATOM   7479  O OG  . SER C 3 49  ? 108.547 127.015 155.045 1.00 153.14 ? 49  SER L OG  1 
ATOM   7480  N N   . PRO C 3 50  ? 105.731 127.404 152.468 1.00 84.79  ? 50  PRO L N   1 
ATOM   7481  C CA  . PRO C 3 50  ? 104.492 126.641 152.596 1.00 84.34  ? 50  PRO L CA  1 
ATOM   7482  C C   . PRO C 3 50  ? 104.599 125.515 153.615 1.00 85.10  ? 50  PRO L C   1 
ATOM   7483  O O   . PRO C 3 50  ? 105.601 124.853 153.610 1.00 83.72  ? 50  PRO L O   1 
ATOM   7484  C CB  . PRO C 3 50  ? 104.380 126.020 151.242 1.00 75.12  ? 50  PRO L CB  1 
ATOM   7485  C CG  . PRO C 3 50  ? 104.972 127.056 150.381 1.00 79.18  ? 50  PRO L CG  1 
ATOM   7486  C CD  . PRO C 3 50  ? 106.267 127.295 151.116 1.00 92.12  ? 50  PRO L CD  1 
ATOM   7487  N N   . LYS C 3 51  ? 103.578 125.315 154.474 1.00 97.65  ? 51  LYS L N   1 
ATOM   7488  C CA  . LYS C 3 51  ? 103.507 124.224 155.443 1.00 85.56  ? 51  LYS L CA  1 
ATOM   7489  C C   . LYS C 3 51  ? 102.329 123.377 154.968 1.00 83.53  ? 51  LYS L C   1 
ATOM   7490  O O   . LYS C 3 51  ? 101.252 123.913 154.680 1.00 77.71  ? 51  LYS L O   1 
ATOM   7491  C CB  . LYS C 3 51  ? 103.328 124.722 156.889 1.00 99.88  ? 51  LYS L CB  1 
ATOM   7492  C CG  . LYS C 3 51  ? 102.890 123.685 157.922 1.00 153.16 ? 51  LYS L CG  1 
ATOM   7493  C CD  . LYS C 3 51  ? 102.508 124.281 159.289 1.00 179.11 ? 51  LYS L CD  1 
ATOM   7494  C CE  . LYS C 3 51  ? 102.246 123.169 160.293 1.00 251.22 ? 51  LYS L CE  1 
ATOM   7495  N NZ  . LYS C 3 51  ? 101.916 123.599 161.682 1.00 247.01 ? 51  LYS L NZ  1 
ATOM   7496  N N   . LEU C 3 52  ? 102.511 122.050 154.931 1.00 69.71  ? 52  LEU L N   1 
ATOM   7497  C CA  . LEU C 3 52  ? 101.417 121.173 154.527 1.00 69.06  ? 52  LEU L CA  1 
ATOM   7498  C C   . LEU C 3 52  ? 100.441 120.953 155.671 1.00 73.20  ? 52  LEU L C   1 
ATOM   7499  O O   . LEU C 3 52  ? 100.922 120.675 156.759 1.00 101.86 ? 52  LEU L O   1 
ATOM   7500  C CB  . LEU C 3 52  ? 102.104 119.872 154.187 1.00 69.24  ? 52  LEU L CB  1 
ATOM   7501  C CG  . LEU C 3 52  ? 101.257 118.697 153.720 1.00 71.16  ? 52  LEU L CG  1 
ATOM   7502  C CD1 . LEU C 3 52  ? 100.296 119.004 152.605 1.00 63.00  ? 52  LEU L CD1 1 
ATOM   7503  C CD2 . LEU C 3 52  ? 102.273 117.659 153.193 1.00 103.17 ? 52  LEU L CD2 1 
ATOM   7504  N N   . LEU C 3 53  ? 99.132  121.123 155.444 1.00 71.73  ? 53  LEU L N   1 
ATOM   7505  C CA  . LEU C 3 53  ? 98.119  120.914 156.478 1.00 78.44  ? 53  LEU L CA  1 
ATOM   7506  C C   . LEU C 3 53  ? 97.469  119.562 156.328 1.00 76.24  ? 53  LEU L C   1 
ATOM   7507  O O   . LEU C 3 53  ? 97.608  118.736 157.233 1.00 128.87 ? 53  LEU L O   1 
ATOM   7508  C CB  . LEU C 3 53  ? 96.992  121.944 156.428 1.00 72.85  ? 53  LEU L CB  1 
ATOM   7509  C CG  . LEU C 3 53  ? 97.463  123.351 156.626 1.00 70.17  ? 53  LEU L CG  1 
ATOM   7510  C CD1 . LEU C 3 53  ? 96.296  124.276 156.487 1.00 96.17  ? 53  LEU L CD1 1 
ATOM   7511  C CD2 . LEU C 3 53  ? 98.071  123.466 157.981 1.00 74.22  ? 53  LEU L CD2 1 
ATOM   7512  N N   . VAL C 3 54  ? 96.741  119.398 155.229 1.00 64.24  ? 54  VAL L N   1 
ATOM   7513  C CA  . VAL C 3 54  ? 96.133  118.120 154.978 1.00 90.73  ? 54  VAL L CA  1 
ATOM   7514  C C   . VAL C 3 54  ? 96.398  117.619 153.565 1.00 74.69  ? 54  VAL L C   1 
ATOM   7515  O O   . VAL C 3 54  ? 96.621  118.393 152.682 1.00 76.98  ? 54  VAL L O   1 
ATOM   7516  C CB  . VAL C 3 54  ? 94.647  118.227 155.245 1.00 81.32  ? 54  VAL L CB  1 
ATOM   7517  C CG1 . VAL C 3 54  ? 94.385  118.944 156.551 1.00 139.60 ? 54  VAL L CG1 1 
ATOM   7518  C CG2 . VAL C 3 54  ? 93.981  118.937 154.160 1.00 79.09  ? 54  VAL L CG2 1 
ATOM   7519  N N   . TYR C 3 55  ? 96.383  116.317 153.404 1.00 78.52  ? 55  TYR L N   1 
ATOM   7520  C CA  . TYR C 3 55  ? 96.491  115.703 152.124 1.00 63.08  ? 55  TYR L CA  1 
ATOM   7521  C C   . TYR C 3 55  ? 95.554  114.519 152.022 1.00 82.65  ? 55  TYR L C   1 
ATOM   7522  O O   . TYR C 3 55  ? 94.924  114.148 152.999 1.00 129.78 ? 55  TYR L O   1 
ATOM   7523  C CB  . TYR C 3 55  ? 97.927  115.258 151.999 1.00 70.74  ? 55  TYR L CB  1 
ATOM   7524  C CG  . TYR C 3 55  ? 98.555  114.298 152.960 1.00 75.06  ? 55  TYR L CG  1 
ATOM   7525  C CD1 . TYR C 3 55  ? 98.448  112.964 152.763 1.00 82.74  ? 55  TYR L CD1 1 
ATOM   7526  C CD2 . TYR C 3 55  ? 99.307  114.765 154.021 1.00 129.31 ? 55  TYR L CD2 1 
ATOM   7527  C CE1 . TYR C 3 55  ? 99.069  112.091 153.655 1.00 140.02 ? 55  TYR L CE1 1 
ATOM   7528  C CE2 . TYR C 3 55  ? 99.941  113.911 154.908 1.00 160.07 ? 55  TYR L CE2 1 
ATOM   7529  C CZ  . TYR C 3 55  ? 99.826  112.554 154.728 1.00 137.46 ? 55  TYR L CZ  1 
ATOM   7530  O OH  . TYR C 3 55  ? 100.479 111.785 155.653 1.00 139.12 ? 55  TYR L OH  1 
ATOM   7531  N N   . PHE C 3 56  ? 95.434  113.940 150.832 1.00 90.27  ? 56  PHE L N   1 
ATOM   7532  C CA  . PHE C 3 56  ? 94.330  113.077 150.474 1.00 87.77  ? 56  PHE L CA  1 
ATOM   7533  C C   . PHE C 3 56  ? 92.988  113.582 150.992 1.00 89.78  ? 56  PHE L C   1 
ATOM   7534  O O   . PHE C 3 56  ? 92.216  112.837 151.608 1.00 133.95 ? 56  PHE L O   1 
ATOM   7535  C CB  . PHE C 3 56  ? 94.705  111.697 150.995 1.00 125.04 ? 56  PHE L CB  1 
ATOM   7536  C CG  . PHE C 3 56  ? 95.878  110.970 150.363 1.00 92.50  ? 56  PHE L CG  1 
ATOM   7537  C CD1 . PHE C 3 56  ? 96.066  110.947 149.029 1.00 56.96  ? 56  PHE L CD1 1 
ATOM   7538  C CD2 . PHE C 3 56  ? 96.725  110.222 151.132 1.00 144.92 ? 56  PHE L CD2 1 
ATOM   7539  C CE1 . PHE C 3 56  ? 97.095  110.279 148.464 1.00 92.43  ? 56  PHE L CE1 1 
ATOM   7540  C CE2 . PHE C 3 56  ? 97.764  109.525 150.578 1.00 160.29 ? 56  PHE L CE2 1 
ATOM   7541  C CZ  . PHE C 3 56  ? 97.950  109.562 149.235 1.00 174.18 ? 56  PHE L CZ  1 
ATOM   7542  N N   . THR C 3 57  ? 92.747  114.871 150.773 1.00 89.13  ? 57  THR L N   1 
ATOM   7543  C CA  . THR C 3 57  ? 91.572  115.618 151.214 1.00 113.09 ? 57  THR L CA  1 
ATOM   7544  C C   . THR C 3 57  ? 91.390  115.794 152.727 1.00 92.30  ? 57  THR L C   1 
ATOM   7545  O O   . THR C 3 57  ? 90.840  116.824 153.096 1.00 119.63 ? 57  THR L O   1 
ATOM   7546  C CB  . THR C 3 57  ? 90.291  115.055 150.633 1.00 111.20 ? 57  THR L CB  1 
ATOM   7547  O OG1 . THR C 3 57  ? 90.584  115.022 149.243 1.00 116.73 ? 57  THR L OG1 1 
ATOM   7548  C CG2 . THR C 3 57  ? 89.109  115.947 150.868 1.00 158.28 ? 57  THR L CG2 1 
ATOM   7549  N N   . SER C 3 58  ? 91.810  114.880 153.581 1.00 75.29  ? 58  SER L N   1 
ATOM   7550  C CA  . SER C 3 58  ? 91.391  114.967 154.956 1.00 117.29 ? 58  SER L CA  1 
ATOM   7551  C C   . SER C 3 58  ? 92.472  114.680 155.990 1.00 125.50 ? 58  SER L C   1 
ATOM   7552  O O   . SER C 3 58  ? 92.309  115.115 157.132 1.00 125.93 ? 58  SER L O   1 
ATOM   7553  C CB  . SER C 3 58  ? 90.227  114.045 155.123 1.00 163.31 ? 58  SER L CB  1 
ATOM   7554  O OG  . SER C 3 58  ? 90.611  112.699 154.909 1.00 159.69 ? 58  SER L OG  1 
ATOM   7555  N N   . THR C 3 59  ? 93.518  113.947 155.593 1.00 120.86 ? 59  THR L N   1 
ATOM   7556  C CA  . THR C 3 59  ? 94.524  113.421 156.492 1.00 116.81 ? 59  THR L CA  1 
ATOM   7557  C C   . THR C 3 59  ? 95.381  114.586 156.939 1.00 121.63 ? 59  THR L C   1 
ATOM   7558  O O   . THR C 3 59  ? 96.084  115.158 156.103 1.00 194.18 ? 59  THR L O   1 
ATOM   7559  C CB  . THR C 3 59  ? 95.362  112.359 155.780 1.00 133.97 ? 59  THR L CB  1 
ATOM   7560  O OG1 . THR C 3 59  ? 94.470  111.247 155.631 1.00 162.92 ? 59  THR L OG1 1 
ATOM   7561  C CG2 . THR C 3 59  ? 96.641  111.978 156.500 1.00 159.57 ? 59  THR L CG2 1 
ATOM   7562  N N   . ARG C 3 60  ? 95.264  114.910 158.229 1.00 120.27 ? 60  ARG L N   1 
ATOM   7563  C CA  . ARG C 3 60  ? 96.089  115.926 158.859 1.00 120.56 ? 60  ARG L CA  1 
ATOM   7564  C C   . ARG C 3 60  ? 97.520  115.424 158.917 1.00 118.10 ? 60  ARG L C   1 
ATOM   7565  O O   . ARG C 3 60  ? 97.757  114.254 159.246 1.00 134.02 ? 60  ARG L O   1 
ATOM   7566  C CB  . ARG C 3 60  ? 95.612  116.282 160.279 1.00 153.85 ? 60  ARG L CB  1 
ATOM   7567  C CG  . ARG C 3 60  ? 94.627  117.423 160.295 1.00 165.74 ? 60  ARG L CG  1 
ATOM   7568  C CD  . ARG C 3 60  ? 94.434  117.961 161.691 1.00 166.28 ? 60  ARG L CD  1 
ATOM   7569  N NE  . ARG C 3 60  ? 93.693  117.054 162.540 1.00 183.69 ? 60  ARG L NE  1 
ATOM   7570  C CZ  . ARG C 3 60  ? 92.398  116.751 162.408 1.00 212.85 ? 60  ARG L CZ  1 
ATOM   7571  N NH1 . ARG C 3 60  ? 91.839  115.936 163.285 1.00 303.68 ? 60  ARG L NH1 1 
ATOM   7572  N NH2 . ARG C 3 60  ? 91.644  117.243 161.425 1.00 138.74 ? 60  ARG L NH2 1 
ATOM   7573  N N   . GLU C 3 61  ? 98.446  116.327 158.585 1.00 110.13 ? 61  GLU L N   1 
ATOM   7574  C CA  . GLU C 3 61  ? 99.865  116.072 158.777 1.00 142.27 ? 61  GLU L CA  1 
ATOM   7575  C C   . GLU C 3 61  ? 100.175 116.106 160.277 1.00 150.28 ? 61  GLU L C   1 
ATOM   7576  O O   . GLU C 3 61  ? 99.462  116.750 161.038 1.00 150.01 ? 61  GLU L O   1 
ATOM   7577  C CB  . GLU C 3 61  ? 100.635 117.081 157.911 1.00 136.91 ? 61  GLU L CB  1 
ATOM   7578  C CG  . GLU C 3 61  ? 102.145 117.108 158.059 1.00 161.50 ? 61  GLU L CG  1 
ATOM   7579  C CD  . GLU C 3 61  ? 102.922 115.821 157.829 1.00 247.01 ? 61  GLU L CD  1 
ATOM   7580  O OE1 . GLU C 3 61  ? 102.352 114.723 158.011 1.00 290.87 ? 61  GLU L OE1 1 
ATOM   7581  O OE2 . GLU C 3 61  ? 104.119 115.924 157.486 1.00 309.25 ? 61  GLU L OE2 1 
ATOM   7582  N N   . SER C 3 62  ? 101.241 115.423 160.716 1.00 161.50 ? 62  SER L N   1 
ATOM   7583  C CA  . SER C 3 62  ? 101.715 115.558 162.091 1.00 203.79 ? 62  SER L CA  1 
ATOM   7584  C C   . SER C 3 62  ? 102.180 116.995 162.398 1.00 195.96 ? 62  SER L C   1 
ATOM   7585  O O   . SER C 3 62  ? 102.799 117.663 161.574 1.00 178.77 ? 62  SER L O   1 
ATOM   7586  C CB  . SER C 3 62  ? 102.783 114.518 162.396 1.00 259.96 ? 62  SER L CB  1 
ATOM   7587  O OG  . SER C 3 62  ? 104.003 114.749 161.701 1.00 245.43 ? 62  SER L OG  1 
ATOM   7588  N N   . GLY C 3 63  ? 101.867 117.484 163.606 1.00 195.00 ? 63  GLY L N   1 
ATOM   7589  C CA  . GLY C 3 63  ? 102.191 118.851 164.001 1.00 197.33 ? 63  GLY L CA  1 
ATOM   7590  C C   . GLY C 3 63  ? 101.201 119.902 163.491 1.00 150.90 ? 63  GLY L C   1 
ATOM   7591  O O   . GLY C 3 63  ? 101.533 121.088 163.449 1.00 204.68 ? 63  GLY L O   1 
ATOM   7592  N N   . VAL C 3 64  ? 99.996  119.452 163.119 1.00 125.93 ? 64  VAL L N   1 
ATOM   7593  C CA  . VAL C 3 64  ? 98.930  120.321 162.663 1.00 138.26 ? 64  VAL L CA  1 
ATOM   7594  C C   . VAL C 3 64  ? 97.843  120.316 163.737 1.00 173.95 ? 64  VAL L C   1 
ATOM   7595  O O   . VAL C 3 64  ? 97.353  119.255 164.128 1.00 203.98 ? 64  VAL L O   1 
ATOM   7596  C CB  . VAL C 3 64  ? 98.392  119.883 161.290 1.00 133.33 ? 64  VAL L CB  1 
ATOM   7597  C CG1 . VAL C 3 64  ? 97.160  120.653 160.865 1.00 157.18 ? 64  VAL L CG1 1 
ATOM   7598  C CG2 . VAL C 3 64  ? 99.445  120.043 160.215 1.00 160.28 ? 64  VAL L CG2 1 
ATOM   7599  N N   . PRO C 3 65  ? 97.433  121.504 164.237 1.00 151.90 ? 65  PRO L N   1 
ATOM   7600  C CA  . PRO C 3 65  ? 96.294  121.599 165.150 1.00 182.28 ? 65  PRO L CA  1 
ATOM   7601  C C   . PRO C 3 65  ? 94.982  121.064 164.588 1.00 177.83 ? 65  PRO L C   1 
ATOM   7602  O O   . PRO C 3 65  ? 94.721  121.230 163.407 1.00 138.08 ? 65  PRO L O   1 
ATOM   7603  C CB  . PRO C 3 65  ? 96.142  123.105 165.344 1.00 237.10 ? 65  PRO L CB  1 
ATOM   7604  C CG  . PRO C 3 65  ? 97.518  123.673 165.068 1.00 242.07 ? 65  PRO L CG  1 
ATOM   7605  C CD  . PRO C 3 65  ? 98.044  122.813 163.953 1.00 173.83 ? 65  PRO L CD  1 
ATOM   7606  N N   . ASP C 3 66  ? 94.162  120.434 165.437 1.00 194.01 ? 66  ASP L N   1 
ATOM   7607  C CA  . ASP C 3 66  ? 93.001  119.678 164.973 1.00 199.14 ? 66  ASP L CA  1 
ATOM   7608  C C   . ASP C 3 66  ? 91.815  120.567 164.606 1.00 151.91 ? 66  ASP L C   1 
ATOM   7609  O O   . ASP C 3 66  ? 90.757  120.038 164.280 1.00 136.09 ? 66  ASP L O   1 
ATOM   7610  C CB  . ASP C 3 66  ? 92.614  118.620 166.007 1.00 237.53 ? 66  ASP L CB  1 
ATOM   7611  C CG  . ASP C 3 66  ? 93.717  117.592 166.190 1.00 345.45 ? 66  ASP L CG  1 
ATOM   7612  O OD1 . ASP C 3 66  ? 93.784  116.654 165.370 1.00 416.09 ? 66  ASP L OD1 1 
ATOM   7613  O OD2 . ASP C 3 66  ? 94.507  117.745 167.148 1.00 360.61 ? 66  ASP L OD2 1 
ATOM   7614  N N   . ARG C 3 67  ? 91.978  121.900 164.665 1.00 168.99 ? 67  ARG L N   1 
ATOM   7615  C CA  . ARG C 3 67  ? 90.992  122.832 164.134 1.00 182.05 ? 67  ARG L CA  1 
ATOM   7616  C C   . ARG C 3 67  ? 90.953  122.859 162.600 1.00 172.36 ? 67  ARG L C   1 
ATOM   7617  O O   . ARG C 3 67  ? 89.984  123.378 162.083 1.00 148.05 ? 67  ARG L O   1 
ATOM   7618  C CB  . ARG C 3 67  ? 91.230  124.239 164.694 1.00 193.19 ? 67  ARG L CB  1 
ATOM   7619  C CG  . ARG C 3 67  ? 92.531  124.917 164.284 1.00 177.44 ? 67  ARG L CG  1 
ATOM   7620  C CD  . ARG C 3 67  ? 92.579  126.289 164.915 1.00 190.27 ? 67  ARG L CD  1 
ATOM   7621  N NE  . ARG C 3 67  ? 93.805  126.998 164.599 1.00 165.17 ? 67  ARG L NE  1 
ATOM   7622  C CZ  . ARG C 3 67  ? 94.940  126.951 165.295 1.00 196.43 ? 67  ARG L CZ  1 
ATOM   7623  N NH1 . ARG C 3 67  ? 96.001  127.616 164.864 1.00 234.36 ? 67  ARG L NH1 1 
ATOM   7624  N NH2 . ARG C 3 67  ? 95.039  126.223 166.397 1.00 182.48 ? 67  ARG L NH2 1 
ATOM   7625  N N   . PHE C 3 68  ? 91.949  122.321 161.875 1.00 147.86 ? 68  PHE L N   1 
ATOM   7626  C CA  . PHE C 3 68  ? 91.890  122.220 160.414 1.00 119.92 ? 68  PHE L CA  1 
ATOM   7627  C C   . PHE C 3 68  ? 91.221  120.914 160.015 1.00 125.13 ? 68  PHE L C   1 
ATOM   7628  O O   . PHE C 3 68  ? 91.767  119.831 160.229 1.00 156.30 ? 68  PHE L O   1 
ATOM   7629  C CB  . PHE C 3 68  ? 93.286  122.286 159.766 1.00 123.35 ? 68  PHE L CB  1 
ATOM   7630  C CG  . PHE C 3 68  ? 94.006  123.577 160.045 1.00 112.92 ? 68  PHE L CG  1 
ATOM   7631  C CD1 . PHE C 3 68  ? 93.656  124.714 159.351 1.00 99.13  ? 68  PHE L CD1 1 
ATOM   7632  C CD2 . PHE C 3 68  ? 94.978  123.662 161.030 1.00 118.96 ? 68  PHE L CD2 1 
ATOM   7633  C CE1 . PHE C 3 68  ? 94.283  125.909 159.616 1.00 121.76 ? 68  PHE L CE1 1 
ATOM   7634  C CE2 . PHE C 3 68  ? 95.588  124.864 161.310 1.00 127.91 ? 68  PHE L CE2 1 
ATOM   7635  C CZ  . PHE C 3 68  ? 95.228  125.978 160.597 1.00 130.56 ? 68  PHE L CZ  1 
ATOM   7636  N N   . ILE C 3 69  ? 90.030  121.024 159.434 1.00 123.95 ? 69  ILE L N   1 
ATOM   7637  C CA  . ILE C 3 69  ? 89.302  119.866 158.966 1.00 149.36 ? 69  ILE L CA  1 
ATOM   7638  C C   . ILE C 3 69  ? 89.117  120.081 157.472 1.00 136.00 ? 69  ILE L C   1 
ATOM   7639  O O   . ILE C 3 69  ? 88.507  121.086 157.050 1.00 140.61 ? 69  ILE L O   1 
ATOM   7640  C CB  . ILE C 3 69  ? 87.960  119.709 159.716 1.00 221.68 ? 69  ILE L CB  1 
ATOM   7641  C CG1 . ILE C 3 69  ? 88.171  119.445 161.209 1.00 280.46 ? 69  ILE L CG1 1 
ATOM   7642  C CG2 . ILE C 3 69  ? 87.106  118.626 159.083 1.00 287.69 ? 69  ILE L CG2 1 
ATOM   7643  C CD1 . ILE C 3 69  ? 86.925  119.572 162.056 1.00 354.53 ? 69  ILE L CD1 1 
ATOM   7644  N N   . GLY C 3 70  ? 89.619  119.104 156.699 1.00 96.90  ? 70  GLY L N   1 
ATOM   7645  C CA  . GLY C 3 70  ? 89.356  119.076 155.270 1.00 129.35 ? 70  GLY L CA  1 
ATOM   7646  C C   . GLY C 3 70  ? 88.312  118.037 154.862 1.00 121.14 ? 70  GLY L C   1 
ATOM   7647  O O   . GLY C 3 70  ? 88.244  116.959 155.455 1.00 133.87 ? 70  GLY L O   1 
ATOM   7648  N N   . SER C 3 71  ? 87.527  118.377 153.832 1.00 112.79 ? 71  SER L N   1 
ATOM   7649  C CA  . SER C 3 71  ? 86.381  117.572 153.446 1.00 138.29 ? 71  SER L CA  1 
ATOM   7650  C C   . SER C 3 71  ? 85.972  117.880 152.007 1.00 123.70 ? 71  SER L C   1 
ATOM   7651  O O   . SER C 3 71  ? 86.401  118.875 151.439 1.00 130.00 ? 71  SER L O   1 
ATOM   7652  C CB  . SER C 3 71  ? 85.234  117.793 154.419 1.00 220.08 ? 71  SER L CB  1 
ATOM   7653  O OG  . SER C 3 71  ? 84.834  119.160 154.486 1.00 234.75 ? 71  SER L OG  1 
ATOM   7654  N N   . GLY C 3 72  ? 85.117  117.023 151.451 1.00 147.75 ? 72  GLY L N   1 
ATOM   7655  C CA  . GLY C 3 72  ? 84.647  117.133 150.080 1.00 144.30 ? 72  GLY L CA  1 
ATOM   7656  C C   . GLY C 3 72  ? 84.938  115.846 149.317 1.00 141.34 ? 72  GLY L C   1 
ATOM   7657  O O   . GLY C 3 72  ? 85.590  114.941 149.848 1.00 132.53 ? 72  GLY L O   1 
ATOM   7658  N N   . SER C 3 73  ? 84.434  115.778 148.073 1.00 125.19 ? 73  SER L N   1 
ATOM   7659  C CA  . SER C 3 73  ? 84.826  114.732 147.130 1.00 163.89 ? 73  SER L CA  1 
ATOM   7660  C C   . SER C 3 73  ? 84.567  115.197 145.702 1.00 136.35 ? 73  SER L C   1 
ATOM   7661  O O   . SER C 3 73  ? 83.834  116.152 145.494 1.00 104.69 ? 73  SER L O   1 
ATOM   7662  C CB  . SER C 3 73  ? 84.127  113.398 147.405 1.00 184.35 ? 73  SER L CB  1 
ATOM   7663  O OG  . SER C 3 73  ? 82.718  113.520 147.277 1.00 230.03 ? 73  SER L OG  1 
ATOM   7664  N N   . GLY C 3 74  ? 85.172  114.491 144.736 1.00 138.27 ? 74  GLY L N   1 
ATOM   7665  C CA  . GLY C 3 74  ? 84.927  114.723 143.324 1.00 166.35 ? 74  GLY L CA  1 
ATOM   7666  C C   . GLY C 3 74  ? 85.651  115.969 142.856 1.00 131.73 ? 74  GLY L C   1 
ATOM   7667  O O   . GLY C 3 74  ? 86.785  115.865 142.435 1.00 130.63 ? 74  GLY L O   1 
ATOM   7668  N N   . THR C 3 75  ? 84.964  117.118 142.940 1.00 140.55 ? 75  THR L N   1 
ATOM   7669  C CA  . THR C 3 75  ? 85.511  118.412 142.550 1.00 152.21 ? 75  THR L CA  1 
ATOM   7670  C C   . THR C 3 75  ? 85.212  119.534 143.553 1.00 155.10 ? 75  THR L C   1 
ATOM   7671  O O   . THR C 3 75  ? 85.887  120.540 143.490 1.00 179.70 ? 75  THR L O   1 
ATOM   7672  C CB  . THR C 3 75  ? 85.018  118.824 141.153 1.00 158.84 ? 75  THR L CB  1 
ATOM   7673  O OG1 . THR C 3 75  ? 83.612  119.090 141.143 1.00 241.79 ? 75  THR L OG1 1 
ATOM   7674  C CG2 . THR C 3 75  ? 85.288  117.779 140.101 1.00 151.30 ? 75  THR L CG2 1 
ATOM   7675  N N   . ASP C 3 76  ? 84.227  119.396 144.452 1.00 133.03 ? 76  ASP L N   1 
ATOM   7676  C CA  . ASP C 3 76  ? 83.961  120.400 145.464 1.00 187.02 ? 76  ASP L CA  1 
ATOM   7677  C C   . ASP C 3 76  ? 84.726  120.009 146.719 1.00 153.84 ? 76  ASP L C   1 
ATOM   7678  O O   . ASP C 3 76  ? 84.371  119.041 147.365 1.00 156.91 ? 76  ASP L O   1 
ATOM   7679  C CB  . ASP C 3 76  ? 82.460  120.553 145.752 1.00 296.57 ? 76  ASP L CB  1 
ATOM   7680  C CG  . ASP C 3 76  ? 81.597  120.940 144.556 1.00 365.42 ? 76  ASP L CG  1 
ATOM   7681  O OD1 . ASP C 3 76  ? 82.054  121.770 143.741 1.00 378.89 ? 76  ASP L OD1 1 
ATOM   7682  O OD2 . ASP C 3 76  ? 80.463  120.409 144.455 1.00 436.50 ? 76  ASP L OD2 1 
ATOM   7683  N N   . PHE C 3 77  ? 85.761  120.779 147.075 1.00 132.89 ? 77  PHE L N   1 
ATOM   7684  C CA  . PHE C 3 77  ? 86.568  120.514 148.254 1.00 110.17 ? 77  PHE L CA  1 
ATOM   7685  C C   . PHE C 3 77  ? 86.652  121.738 149.156 1.00 111.22 ? 77  PHE L C   1 
ATOM   7686  O O   . PHE C 3 77  ? 86.655  122.864 148.667 1.00 107.71 ? 77  PHE L O   1 
ATOM   7687  C CB  . PHE C 3 77  ? 87.975  120.175 147.835 1.00 130.48 ? 77  PHE L CB  1 
ATOM   7688  C CG  . PHE C 3 77  ? 88.098  118.883 147.087 1.00 117.07 ? 77  PHE L CG  1 
ATOM   7689  C CD1 . PHE C 3 77  ? 88.100  117.707 147.795 1.00 118.31 ? 77  PHE L CD1 1 
ATOM   7690  C CD2 . PHE C 3 77  ? 88.245  118.856 145.707 1.00 113.63 ? 77  PHE L CD2 1 
ATOM   7691  C CE1 . PHE C 3 77  ? 88.225  116.508 147.130 1.00 165.46 ? 77  PHE L CE1 1 
ATOM   7692  C CE2 . PHE C 3 77  ? 88.359  117.650 145.042 1.00 117.30 ? 77  PHE L CE2 1 
ATOM   7693  C CZ  . PHE C 3 77  ? 88.357  116.477 145.756 1.00 142.91 ? 77  PHE L CZ  1 
ATOM   7694  N N   . THR C 3 78  ? 86.722  121.503 150.473 1.00 114.73 ? 78  THR L N   1 
ATOM   7695  C CA  . THR C 3 78  ? 86.676  122.567 151.473 1.00 120.97 ? 78  THR L CA  1 
ATOM   7696  C C   . THR C 3 78  ? 87.609  122.285 152.640 1.00 104.26 ? 78  THR L C   1 
ATOM   7697  O O   . THR C 3 78  ? 87.554  121.220 153.264 1.00 157.86 ? 78  THR L O   1 
ATOM   7698  C CB  . THR C 3 78  ? 85.283  122.779 152.074 1.00 166.18 ? 78  THR L CB  1 
ATOM   7699  O OG1 . THR C 3 78  ? 84.771  121.524 152.513 1.00 179.35 ? 78  THR L OG1 1 
ATOM   7700  C CG2 . THR C 3 78  ? 84.334  123.379 151.075 1.00 204.66 ? 78  THR L CG2 1 
ATOM   7701  N N   . LEU C 3 79  ? 88.476  123.267 152.890 1.00 91.11  ? 79  LEU L N   1 
ATOM   7702  C CA  . LEU C 3 79  ? 89.221  123.321 154.121 1.00 110.09 ? 79  LEU L CA  1 
ATOM   7703  C C   . LEU C 3 79  ? 88.422  124.229 155.047 1.00 153.74 ? 79  LEU L C   1 
ATOM   7704  O O   . LEU C 3 79  ? 88.045  125.333 154.631 1.00 127.81 ? 79  LEU L O   1 
ATOM   7705  C CB  . LEU C 3 79  ? 90.661  123.817 153.857 1.00 72.98  ? 79  LEU L CB  1 
ATOM   7706  C CG  . LEU C 3 79  ? 91.423  124.203 155.113 1.00 117.21 ? 79  LEU L CG  1 
ATOM   7707  C CD1 . LEU C 3 79  ? 91.733  122.970 155.971 1.00 130.01 ? 79  LEU L CD1 1 
ATOM   7708  C CD2 . LEU C 3 79  ? 92.662  124.984 154.791 1.00 118.26 ? 79  LEU L CD2 1 
ATOM   7709  N N   . THR C 3 80  ? 88.197  123.761 156.294 1.00 175.96 ? 80  THR L N   1 
ATOM   7710  C CA  . THR C 3 80  ? 87.447  124.521 157.290 1.00 154.98 ? 80  THR L CA  1 
ATOM   7711  C C   . THR C 3 80  ? 88.281  124.646 158.555 1.00 129.84 ? 80  THR L C   1 
ATOM   7712  O O   . THR C 3 80  ? 89.039  123.720 158.878 1.00 156.14 ? 80  THR L O   1 
ATOM   7713  C CB  . THR C 3 80  ? 86.107  123.869 157.592 1.00 203.35 ? 80  THR L CB  1 
ATOM   7714  O OG1 . THR C 3 80  ? 86.342  122.599 158.205 1.00 242.24 ? 80  THR L OG1 1 
ATOM   7715  C CG2 . THR C 3 80  ? 85.274  123.712 156.340 1.00 260.51 ? 80  THR L CG2 1 
ATOM   7716  N N   . ILE C 3 81  ? 88.184  125.799 159.222 1.00 120.49 ? 81  ILE L N   1 
ATOM   7717  C CA  . ILE C 3 81  ? 88.903  126.033 160.462 1.00 140.11 ? 81  ILE L CA  1 
ATOM   7718  C C   . ILE C 3 81  ? 87.791  126.223 161.476 1.00 181.01 ? 81  ILE L C   1 
ATOM   7719  O O   . ILE C 3 81  ? 87.003  127.146 161.306 1.00 221.80 ? 81  ILE L O   1 
ATOM   7720  C CB  . ILE C 3 81  ? 89.901  127.223 160.413 1.00 137.06 ? 81  ILE L CB  1 
ATOM   7721  C CG1 . ILE C 3 81  ? 90.745  127.281 159.126 1.00 161.24 ? 81  ILE L CG1 1 
ATOM   7722  C CG2 . ILE C 3 81  ? 90.816  127.195 161.625 1.00 127.35 ? 81  ILE L CG2 1 
ATOM   7723  C CD1 . ILE C 3 81  ? 91.696  128.476 159.046 1.00 204.51 ? 81  ILE L CD1 1 
ATOM   7724  N N   . SER C 3 82  ? 87.725  125.351 162.498 1.00 162.03 ? 82  SER L N   1 
ATOM   7725  C CA  . SER C 3 82  ? 86.576  125.279 163.399 1.00 199.03 ? 82  SER L CA  1 
ATOM   7726  C C   . SER C 3 82  ? 86.440  126.518 164.284 1.00 216.71 ? 82  SER L C   1 
ATOM   7727  O O   . SER C 3 82  ? 85.325  126.906 164.633 1.00 243.47 ? 82  SER L O   1 
ATOM   7728  C CB  . SER C 3 82  ? 86.641  124.055 164.252 1.00 215.55 ? 82  SER L CB  1 
ATOM   7729  O OG  . SER C 3 82  ? 86.548  122.898 163.442 1.00 279.47 ? 82  SER L OG  1 
ATOM   7730  N N   . SER C 3 83  ? 87.578  127.115 164.650 1.00 193.68 ? 83  SER L N   1 
ATOM   7731  C CA  . SER C 3 83  ? 87.615  128.265 165.541 1.00 203.96 ? 83  SER L CA  1 
ATOM   7732  C C   . SER C 3 83  ? 88.946  128.993 165.357 1.00 182.56 ? 83  SER L C   1 
ATOM   7733  O O   . SER C 3 83  ? 89.936  128.673 166.039 1.00 142.77 ? 83  SER L O   1 
ATOM   7734  C CB  . SER C 3 83  ? 87.383  127.848 166.977 1.00 252.62 ? 83  SER L CB  1 
ATOM   7735  O OG  . SER C 3 83  ? 87.245  128.984 167.825 1.00 266.12 ? 83  SER L OG  1 
ATOM   7736  N N   . VAL C 3 84  ? 88.923  129.962 164.412 1.00 131.58 ? 84  VAL L N   1 
ATOM   7737  C CA  . VAL C 3 84  ? 90.078  130.748 163.962 1.00 105.31 ? 84  VAL L CA  1 
ATOM   7738  C C   . VAL C 3 84  ? 90.795  131.406 165.130 1.00 123.07 ? 84  VAL L C   1 
ATOM   7739  O O   . VAL C 3 84  ? 90.157  132.040 165.977 1.00 193.08 ? 84  VAL L O   1 
ATOM   7740  C CB  . VAL C 3 84  ? 89.607  131.823 162.972 1.00 115.78 ? 84  VAL L CB  1 
ATOM   7741  C CG1 . VAL C 3 84  ? 90.525  133.034 162.858 1.00 144.56 ? 84  VAL L CG1 1 
ATOM   7742  C CG2 . VAL C 3 84  ? 89.350  131.175 161.625 1.00 176.67 ? 84  VAL L CG2 1 
ATOM   7743  N N   . GLN C 3 85  ? 92.120  131.256 165.159 1.00 103.74 ? 85  GLN L N   1 
ATOM   7744  C CA  . GLN C 3 85  ? 92.961  131.954 166.115 1.00 138.97 ? 85  GLN L CA  1 
ATOM   7745  C C   . GLN C 3 85  ? 93.717  133.092 165.417 1.00 138.20 ? 85  GLN L C   1 
ATOM   7746  O O   . GLN C 3 85  ? 93.803  133.153 164.206 1.00 123.15 ? 85  GLN L O   1 
ATOM   7747  C CB  . GLN C 3 85  ? 93.861  130.926 166.798 1.00 144.94 ? 85  GLN L CB  1 
ATOM   7748  C CG  . GLN C 3 85  ? 93.057  129.770 167.399 1.00 138.86 ? 85  GLN L CG  1 
ATOM   7749  C CD  . GLN C 3 85  ? 93.746  128.990 168.493 1.00 217.79 ? 85  GLN L CD  1 
ATOM   7750  O OE1 . GLN C 3 85  ? 94.773  129.386 169.058 1.00 213.54 ? 85  GLN L OE1 1 
ATOM   7751  N NE2 . GLN C 3 85  ? 93.155  127.847 168.811 1.00 222.90 ? 85  GLN L NE2 1 
ATOM   7752  N N   . ALA C 3 86  ? 94.259  134.013 166.207 1.00 170.69 ? 86  ALA L N   1 
ATOM   7753  C CA  . ALA C 3 86  ? 94.998  135.141 165.666 1.00 177.06 ? 86  ALA L CA  1 
ATOM   7754  C C   . ALA C 3 86  ? 96.214  134.656 164.882 1.00 166.90 ? 86  ALA L C   1 
ATOM   7755  O O   . ALA C 3 86  ? 96.676  135.367 163.982 1.00 187.54 ? 86  ALA L O   1 
ATOM   7756  C CB  . ALA C 3 86  ? 95.403  136.067 166.799 1.00 232.47 ? 86  ALA L CB  1 
ATOM   7757  N N   . GLU C 3 87  ? 96.740  133.460 165.239 1.00 159.33 ? 87  GLU L N   1 
ATOM   7758  C CA  . GLU C 3 87  ? 97.925  132.908 164.588 1.00 182.81 ? 87  GLU L CA  1 
ATOM   7759  C C   . GLU C 3 87  ? 97.632  132.386 163.184 1.00 125.65 ? 87  GLU L C   1 
ATOM   7760  O O   . GLU C 3 87  ? 98.596  132.038 162.509 1.00 166.40 ? 87  GLU L O   1 
ATOM   7761  C CB  . GLU C 3 87  ? 98.587  131.833 165.460 1.00 206.22 ? 87  GLU L CB  1 
ATOM   7762  C CG  . GLU C 3 87  ? 97.783  130.556 165.657 1.00 259.91 ? 87  GLU L CG  1 
ATOM   7763  C CD  . GLU C 3 87  ? 98.360  129.525 166.615 1.00 336.66 ? 87  GLU L CD  1 
ATOM   7764  O OE1 . GLU C 3 87  ? 98.859  129.921 167.690 1.00 376.17 ? 87  GLU L OE1 1 
ATOM   7765  O OE2 . GLU C 3 87  ? 98.285  128.306 166.279 1.00 331.13 ? 87  GLU L OE2 1 
ATOM   7766  N N   . ASP C 3 88  ? 96.360  132.356 162.748 1.00 110.87 ? 88  ASP L N   1 
ATOM   7767  C CA  . ASP C 3 88  ? 95.948  131.677 161.527 1.00 128.56 ? 88  ASP L CA  1 
ATOM   7768  C C   . ASP C 3 88  ? 95.950  132.575 160.284 1.00 115.83 ? 88  ASP L C   1 
ATOM   7769  O O   . ASP C 3 88  ? 95.713  132.048 159.200 1.00 81.02  ? 88  ASP L O   1 
ATOM   7770  C CB  . ASP C 3 88  ? 94.568  131.021 161.679 1.00 108.03 ? 88  ASP L CB  1 
ATOM   7771  C CG  . ASP C 3 88  ? 94.609  129.812 162.598 1.00 170.23 ? 88  ASP L CG  1 
ATOM   7772  O OD1 . ASP C 3 88  ? 95.665  129.106 162.614 1.00 172.48 ? 88  ASP L OD1 1 
ATOM   7773  O OD2 . ASP C 3 88  ? 93.595  129.568 163.292 1.00 208.49 ? 88  ASP L OD2 1 
ATOM   7774  N N   . LEU C 3 89  ? 96.249  133.874 160.386 1.00 98.78  ? 89  LEU L N   1 
ATOM   7775  C CA  . LEU C 3 89  ? 96.230  134.687 159.190 1.00 107.04 ? 89  LEU L CA  1 
ATOM   7776  C C   . LEU C 3 89  ? 97.395  134.309 158.273 1.00 111.22 ? 89  LEU L C   1 
ATOM   7777  O O   . LEU C 3 89  ? 98.545  134.262 158.738 1.00 137.94 ? 89  LEU L O   1 
ATOM   7778  C CB  . LEU C 3 89  ? 96.239  136.155 159.613 1.00 148.27 ? 89  LEU L CB  1 
ATOM   7779  C CG  . LEU C 3 89  ? 97.555  136.787 160.028 1.00 177.27 ? 89  LEU L CG  1 
ATOM   7780  C CD1 . LEU C 3 89  ? 98.160  137.520 158.825 1.00 168.97 ? 89  LEU L CD1 1 
ATOM   7781  C CD2 . LEU C 3 89  ? 97.356  137.747 161.205 1.00 259.11 ? 89  LEU L CD2 1 
ATOM   7782  N N   . ALA C 3 90  ? 97.075  134.063 156.977 1.00 94.36  ? 90  ALA L N   1 
ATOM   7783  C CA  . ALA C 3 90  ? 97.944  133.426 155.995 1.00 92.59  ? 90  ALA L CA  1 
ATOM   7784  C C   . ALA C 3 90  ? 97.299  133.440 154.616 1.00 85.25  ? 90  ALA L C   1 
ATOM   7785  O O   . ALA C 3 90  ? 96.122  133.815 154.516 1.00 114.57 ? 90  ALA L O   1 
ATOM   7786  C CB  . ALA C 3 90  ? 98.165  132.000 156.400 1.00 106.78 ? 90  ALA L CB  1 
ATOM   7787  N N   . LEU C 3 91  ? 98.044  133.010 153.575 1.00 89.59  ? 91  LEU L N   1 
ATOM   7788  C CA  . LEU C 3 91  ? 97.404  132.526 152.354 1.00 106.77 ? 91  LEU L CA  1 
ATOM   7789  C C   . LEU C 3 91  ? 97.341  131.026 152.463 1.00 85.52  ? 91  LEU L C   1 
ATOM   7790  O O   . LEU C 3 91  ? 98.290  130.431 152.956 1.00 120.80 ? 91  LEU L O   1 
ATOM   7791  C CB  . LEU C 3 91  ? 98.130  132.886 151.059 1.00 81.73  ? 91  LEU L CB  1 
ATOM   7792  C CG  . LEU C 3 91  ? 98.161  134.347 150.689 1.00 138.16 ? 91  LEU L CG  1 
ATOM   7793  C CD1 . LEU C 3 91  ? 99.286  135.044 151.468 1.00 229.60 ? 91  LEU L CD1 1 
ATOM   7794  C CD2 . LEU C 3 91  ? 98.299  134.501 149.178 1.00 226.47 ? 91  LEU L CD2 1 
ATOM   7795  N N   . TYR C 3 92  ? 96.223  130.460 152.003 1.00 84.39  ? 92  TYR L N   1 
ATOM   7796  C CA  . TYR C 3 92  ? 96.045  129.027 151.960 1.00 75.41  ? 92  TYR L CA  1 
ATOM   7797  C C   . TYR C 3 92  ? 95.915  128.619 150.507 1.00 53.90  ? 92  TYR L C   1 
ATOM   7798  O O   . TYR C 3 92  ? 95.088  129.163 149.802 1.00 94.49  ? 92  TYR L O   1 
ATOM   7799  C CB  . TYR C 3 92  ? 94.807  128.597 152.730 1.00 66.84  ? 92  TYR L CB  1 
ATOM   7800  C CG  . TYR C 3 92  ? 94.929  128.833 154.213 1.00 71.30  ? 92  TYR L CG  1 
ATOM   7801  C CD1 . TYR C 3 92  ? 94.827  130.083 154.745 1.00 68.58  ? 92  TYR L CD1 1 
ATOM   7802  C CD2 . TYR C 3 92  ? 95.132  127.782 155.082 1.00 104.80 ? 92  TYR L CD2 1 
ATOM   7803  C CE1 . TYR C 3 92  ? 94.937  130.276 156.106 1.00 102.08 ? 92  TYR L CE1 1 
ATOM   7804  C CE2 . TYR C 3 92  ? 95.233  127.967 156.450 1.00 107.77 ? 92  TYR L CE2 1 
ATOM   7805  C CZ  . TYR C 3 92  ? 95.155  129.223 156.968 1.00 83.24  ? 92  TYR L CZ  1 
ATOM   7806  O OH  . TYR C 3 92  ? 95.244  129.376 158.309 1.00 96.63  ? 92  TYR L OH  1 
ATOM   7807  N N   . TYR C 3 93  ? 96.711  127.653 150.076 1.00 50.54  ? 93  TYR L N   1 
ATOM   7808  C CA  . TYR C 3 93  ? 96.613  127.116 148.733 1.00 72.35  ? 93  TYR L CA  1 
ATOM   7809  C C   . TYR C 3 93  ? 96.089  125.687 148.724 1.00 66.83  ? 93  TYR L C   1 
ATOM   7810  O O   . TYR C 3 93  ? 96.504  124.885 149.532 1.00 50.94  ? 93  TYR L O   1 
ATOM   7811  C CB  . TYR C 3 93  ? 98.004  127.117 148.112 1.00 76.59  ? 93  TYR L CB  1 
ATOM   7812  C CG  . TYR C 3 93  ? 98.742  128.449 148.105 1.00 66.31  ? 93  TYR L CG  1 
ATOM   7813  C CD1 . TYR C 3 93  ? 98.625  129.351 147.125 1.00 95.58  ? 93  TYR L CD1 1 
ATOM   7814  C CD2 . TYR C 3 93  ? 99.559  128.784 149.098 1.00 78.28  ? 93  TYR L CD2 1 
ATOM   7815  C CE1 . TYR C 3 93  ? 99.324  130.536 147.142 1.00 105.72 ? 93  TYR L CE1 1 
ATOM   7816  C CE2 . TYR C 3 93  ? 100.260 129.947 149.154 1.00 90.04  ? 93  TYR L CE2 1 
ATOM   7817  C CZ  . TYR C 3 93  ? 100.146 130.856 148.183 1.00 83.65  ? 93  TYR L CZ  1 
ATOM   7818  O OH  . TYR C 3 93  ? 100.918 131.982 148.378 1.00 131.52 ? 93  TYR L OH  1 
ATOM   7819  N N   . CYS C 3 94  ? 95.180  125.371 147.794 1.00 72.43  ? 94  CYS L N   1 
ATOM   7820  C CA  . CYS C 3 94  ? 94.872  123.983 147.543 1.00 62.85  ? 94  CYS L CA  1 
ATOM   7821  C C   . CYS C 3 94  ? 95.824  123.529 146.445 1.00 58.96  ? 94  CYS L C   1 
ATOM   7822  O O   . CYS C 3 94  ? 96.202  124.314 145.631 1.00 73.89  ? 94  CYS L O   1 
ATOM   7823  C CB  . CYS C 3 94  ? 93.407  123.788 147.163 1.00 88.20  ? 94  CYS L CB  1 
ATOM   7824  S SG  . CYS C 3 94  ? 92.849  124.400 145.541 1.00 130.33 ? 94  CYS L SG  1 
ATOM   7825  N N   . GLN C 3 95  ? 96.197  122.256 146.416 1.00 64.45  ? 95  GLN L N   1 
ATOM   7826  C CA  . GLN C 3 95  ? 96.948  121.582 145.371 1.00 54.67  ? 95  GLN L CA  1 
ATOM   7827  C C   . GLN C 3 95  ? 96.299  120.221 145.083 1.00 65.89  ? 95  GLN L C   1 
ATOM   7828  O O   . GLN C 3 95  ? 95.928  119.516 146.023 1.00 91.87  ? 95  GLN L O   1 
ATOM   7829  C CB  . GLN C 3 95  ? 98.345  121.313 145.916 1.00 62.28  ? 95  GLN L CB  1 
ATOM   7830  C CG  . GLN C 3 95  ? 99.338  120.808 144.908 1.00 80.98  ? 95  GLN L CG  1 
ATOM   7831  C CD  . GLN C 3 95  ? 100.273 119.801 145.522 1.00 83.93  ? 95  GLN L CD  1 
ATOM   7832  O OE1 . GLN C 3 95  ? 100.933 120.044 146.501 1.00 61.47  ? 95  GLN L OE1 1 
ATOM   7833  N NE2 . GLN C 3 95  ? 100.357 118.617 144.954 1.00 129.78 ? 95  GLN L NE2 1 
ATOM   7834  N N   . GLN C 3 96  ? 96.201  119.842 143.808 1.00 59.61  ? 96  GLN L N   1 
ATOM   7835  C CA  . GLN C 3 96  ? 95.891  118.481 143.471 1.00 67.06  ? 96  GLN L CA  1 
ATOM   7836  C C   . GLN C 3 96  ? 97.166  117.642 143.579 1.00 58.10  ? 96  GLN L C   1 
ATOM   7837  O O   . GLN C 3 96  ? 98.223  118.141 143.223 1.00 94.47  ? 96  GLN L O   1 
ATOM   7838  C CB  . GLN C 3 96  ? 95.229  118.325 142.088 1.00 63.00  ? 96  GLN L CB  1 
ATOM   7839  C CG  . GLN C 3 96  ? 96.075  117.696 140.937 1.00 43.38  ? 96  GLN L CG  1 
ATOM   7840  C CD  . GLN C 3 96  ? 96.826  118.814 140.387 1.00 86.49  ? 96  GLN L CD  1 
ATOM   7841  O OE1 . GLN C 3 96  ? 96.898  119.857 141.037 1.00 106.29 ? 96  GLN L OE1 1 
ATOM   7842  N NE2 . GLN C 3 96  ? 97.319  118.662 139.171 1.00 121.43 ? 96  GLN L NE2 1 
ATOM   7843  N N   . HIS C 3 97  ? 97.072  116.388 144.010 1.00 54.82  ? 97  HIS L N   1 
ATOM   7844  C CA  . HIS C 3 97  ? 98.107  115.442 143.643 1.00 69.53  ? 97  HIS L CA  1 
ATOM   7845  C C   . HIS C 3 97  ? 97.653  114.253 142.807 1.00 54.82  ? 97  HIS L C   1 
ATOM   7846  O O   . HIS C 3 97  ? 98.198  113.172 142.947 1.00 75.16  ? 97  HIS L O   1 
ATOM   7847  C CB  . HIS C 3 97  ? 98.932  115.137 144.871 1.00 71.03  ? 97  HIS L CB  1 
ATOM   7848  C CG  . HIS C 3 97  ? 98.212  114.770 146.029 1.00 66.79  ? 97  HIS L CG  1 
ATOM   7849  N ND1 . HIS C 3 97  ? 97.919  115.669 147.005 1.00 95.90  ? 97  HIS L ND1 1 
ATOM   7850  C CD2 . HIS C 3 97  ? 97.834  113.631 146.384 1.00 75.32  ? 97  HIS L CD2 1 
ATOM   7851  C CE1 . HIS C 3 97  ? 97.328  115.016 147.951 1.00 100.21 ? 97  HIS L CE1 1 
ATOM   7852  N NE2 . HIS C 3 97  ? 97.269  113.768 147.610 1.00 82.49  ? 97  HIS L NE2 1 
ATOM   7853  N N   . TYR C 3 98  ? 96.707  114.457 141.940 1.00 43.43  ? 98  TYR L N   1 
ATOM   7854  C CA  . TYR C 3 98  ? 96.288  113.402 141.089 1.00 68.10  ? 98  TYR L CA  1 
ATOM   7855  C C   . TYR C 3 98  ? 97.143  113.360 139.835 1.00 66.13  ? 98  TYR L C   1 
ATOM   7856  O O   . TYR C 3 98  ? 97.195  112.287 139.240 1.00 68.10  ? 98  TYR L O   1 
ATOM   7857  C CB  . TYR C 3 98  ? 94.778  113.531 140.877 1.00 73.91  ? 98  TYR L CB  1 
ATOM   7858  C CG  . TYR C 3 98  ? 94.132  112.456 140.020 1.00 78.48  ? 98  TYR L CG  1 
ATOM   7859  C CD1 . TYR C 3 98  ? 94.072  112.583 138.641 1.00 101.53 ? 98  TYR L CD1 1 
ATOM   7860  C CD2 . TYR C 3 98  ? 93.635  111.299 140.579 1.00 72.19  ? 98  TYR L CD2 1 
ATOM   7861  C CE1 . TYR C 3 98  ? 93.480  111.597 137.866 1.00 140.65 ? 98  TYR L CE1 1 
ATOM   7862  C CE2 . TYR C 3 98  ? 93.072  110.294 139.824 1.00 110.67 ? 98  TYR L CE2 1 
ATOM   7863  C CZ  . TYR C 3 98  ? 92.973  110.444 138.457 1.00 169.62 ? 98  TYR L CZ  1 
ATOM   7864  O OH  . TYR C 3 98  ? 92.390  109.417 137.755 1.00 239.65 ? 98  TYR L OH  1 
ATOM   7865  N N   . THR C 3 99  ? 97.776  114.437 139.426 1.00 63.69  ? 99  THR L N   1 
ATOM   7866  C CA  . THR C 3 99  ? 98.846  114.217 138.461 1.00 84.23  ? 99  THR L CA  1 
ATOM   7867  C C   . THR C 3 99  ? 100.151 114.924 138.802 1.00 70.45  ? 99  THR L C   1 
ATOM   7868  O O   . THR C 3 99  ? 100.191 115.901 139.517 1.00 81.27  ? 99  THR L O   1 
ATOM   7869  C CB  . THR C 3 99  ? 98.521  114.674 137.050 1.00 123.35 ? 99  THR L CB  1 
ATOM   7870  O OG1 . THR C 3 99  ? 98.368  116.092 137.118 1.00 184.04 ? 99  THR L OG1 1 
ATOM   7871  C CG2 . THR C 3 99  ? 97.293  113.953 136.518 1.00 161.71 ? 99  THR L CG2 1 
ATOM   7872  N N   . ILE C 3 100 ? 101.224 114.386 138.268 1.00 58.33  ? 100 ILE L N   1 
ATOM   7873  C CA  . ILE C 3 100 ? 102.501 115.061 138.365 1.00 69.72  ? 100 ILE L CA  1 
ATOM   7874  C C   . ILE C 3 100 ? 102.776 115.436 136.929 1.00 51.17  ? 100 ILE L C   1 
ATOM   7875  O O   . ILE C 3 100 ? 102.787 114.546 136.123 1.00 39.38  ? 100 ILE L O   1 
ATOM   7876  C CB  . ILE C 3 100 ? 103.699 114.327 139.042 1.00 61.99  ? 100 ILE L CB  1 
ATOM   7877  C CG1 . ILE C 3 100 ? 104.910 114.352 138.132 1.00 56.81  ? 100 ILE L CG1 1 
ATOM   7878  C CG2 . ILE C 3 100 ? 103.457 112.877 139.535 1.00 55.57  ? 100 ILE L CG2 1 
ATOM   7879  C CD1 . ILE C 3 100 ? 106.023 113.734 138.880 1.00 104.34 ? 100 ILE L CD1 1 
ATOM   7880  N N   . PRO C 3 101 ? 103.027 116.737 136.610 1.00 63.51  ? 101 PRO L N   1 
ATOM   7881  C CA  . PRO C 3 101 ? 103.209 117.837 137.578 1.00 66.90  ? 101 PRO L CA  1 
ATOM   7882  C C   . PRO C 3 101 ? 101.931 118.274 138.306 1.00 62.36  ? 101 PRO L C   1 
ATOM   7883  O O   . PRO C 3 101 ? 100.852 118.284 137.697 1.00 58.44  ? 101 PRO L O   1 
ATOM   7884  C CB  . PRO C 3 101 ? 103.531 118.979 136.683 1.00 66.40  ? 101 PRO L CB  1 
ATOM   7885  C CG  . PRO C 3 101 ? 102.741 118.686 135.452 1.00 88.26  ? 101 PRO L CG  1 
ATOM   7886  C CD  . PRO C 3 101 ? 103.133 117.246 135.262 1.00 72.17  ? 101 PRO L CD  1 
ATOM   7887  N N   . PRO C 3 102 ? 102.013 118.582 139.605 1.00 41.34  ? 102 PRO L N   1 
ATOM   7888  C CA  . PRO C 3 102 ? 100.873 119.076 140.331 1.00 53.99  ? 102 PRO L CA  1 
ATOM   7889  C C   . PRO C 3 102 ? 100.584 120.510 139.939 1.00 89.05  ? 102 PRO L C   1 
ATOM   7890  O O   . PRO C 3 102 ? 101.396 121.144 139.250 1.00 136.39 ? 102 PRO L O   1 
ATOM   7891  C CB  . PRO C 3 102 ? 101.309 119.059 141.788 1.00 53.80  ? 102 PRO L CB  1 
ATOM   7892  C CG  . PRO C 3 102 ? 102.775 119.187 141.757 1.00 48.80  ? 102 PRO L CG  1 
ATOM   7893  C CD  . PRO C 3 102 ? 103.182 118.494 140.452 1.00 41.72  ? 102 PRO L CD  1 
ATOM   7894  N N   . THR C 3 103 ? 99.424  121.022 140.413 1.00 64.80  ? 103 THR L N   1 
ATOM   7895  C CA  . THR C 3 103 ? 99.045  122.405 140.159 1.00 87.24  ? 103 THR L CA  1 
ATOM   7896  C C   . THR C 3 103 ? 98.343  122.978 141.364 1.00 70.36  ? 103 THR L C   1 
ATOM   7897  O O   . THR C 3 103 ? 97.794  122.237 142.124 1.00 65.03  ? 103 THR L O   1 
ATOM   7898  C CB  . THR C 3 103 ? 98.178  122.540 138.903 1.00 114.19 ? 103 THR L CB  1 
ATOM   7899  O OG1 . THR C 3 103 ? 97.205  121.540 138.935 1.00 70.78  ? 103 THR L OG1 1 
ATOM   7900  C CG2 . THR C 3 103 ? 98.870  122.247 137.592 1.00 206.47 ? 103 THR L CG2 1 
ATOM   7901  N N   . PHE C 3 104 ? 98.340  124.297 141.514 1.00 69.54  ? 104 PHE L N   1 
ATOM   7902  C CA  . PHE C 3 104 ? 97.822  124.857 142.735 1.00 66.71  ? 104 PHE L CA  1 
ATOM   7903  C C   . PHE C 3 104 ? 96.759  125.933 142.466 1.00 85.88  ? 104 PHE L C   1 
ATOM   7904  O O   . PHE C 3 104 ? 96.725  126.596 141.442 1.00 120.85 ? 104 PHE L O   1 
ATOM   7905  C CB  . PHE C 3 104 ? 98.996  125.481 143.447 1.00 93.97  ? 104 PHE L CB  1 
ATOM   7906  C CG  . PHE C 3 104 ? 100.164 124.651 143.896 1.00 91.02  ? 104 PHE L CG  1 
ATOM   7907  C CD1 . PHE C 3 104 ? 101.120 124.202 143.012 1.00 102.81 ? 104 PHE L CD1 1 
ATOM   7908  C CD2 . PHE C 3 104 ? 100.338 124.402 145.244 1.00 73.65  ? 104 PHE L CD2 1 
ATOM   7909  C CE1 . PHE C 3 104 ? 102.188 123.491 143.502 1.00 71.51  ? 104 PHE L CE1 1 
ATOM   7910  C CE2 . PHE C 3 104 ? 101.415 123.700 145.740 1.00 49.19  ? 104 PHE L CE2 1 
ATOM   7911  C CZ  . PHE C 3 104 ? 102.312 123.267 144.848 1.00 56.11  ? 104 PHE L CZ  1 
ATOM   7912  N N   . GLY C 3 105 ? 95.894  126.169 143.456 1.00 104.45 ? 105 GLY L N   1 
ATOM   7913  C CA  . GLY C 3 105 ? 95.064  127.355 143.573 1.00 122.85 ? 105 GLY L CA  1 
ATOM   7914  C C   . GLY C 3 105 ? 95.821  128.677 143.690 1.00 83.67  ? 105 GLY L C   1 
ATOM   7915  O O   . GLY C 3 105 ? 96.947  128.740 144.049 1.00 79.52  ? 105 GLY L O   1 
ATOM   7916  N N   . GLY C 3 106 ? 95.163  129.759 143.340 1.00 129.93 ? 106 GLY L N   1 
ATOM   7917  C CA  . GLY C 3 106 ? 95.726  131.078 143.510 1.00 159.85 ? 106 GLY L CA  1 
ATOM   7918  C C   . GLY C 3 106 ? 95.619  131.557 144.950 1.00 128.94 ? 106 GLY L C   1 
ATOM   7919  O O   . GLY C 3 106 ? 96.146  132.629 145.256 1.00 161.96 ? 106 GLY L O   1 
ATOM   7920  N N   . GLY C 3 107 ? 94.945  130.793 145.812 1.00 84.07  ? 107 GLY L N   1 
ATOM   7921  C CA  . GLY C 3 107 ? 95.099  130.997 147.246 1.00 128.66 ? 107 GLY L CA  1 
ATOM   7922  C C   . GLY C 3 107 ? 94.116  131.993 147.884 1.00 117.45 ? 107 GLY L C   1 
ATOM   7923  O O   . GLY C 3 107 ? 93.855  133.041 147.305 1.00 125.41 ? 107 GLY L O   1 
ATOM   7924  N N   . THR C 3 108 ? 93.623  131.649 149.088 1.00 102.74 ? 108 THR L N   1 
ATOM   7925  C CA  . THR C 3 108 ? 92.673  132.431 149.855 1.00 97.42  ? 108 THR L CA  1 
ATOM   7926  C C   . THR C 3 108 ? 93.412  133.155 150.969 1.00 87.55  ? 108 THR L C   1 
ATOM   7927  O O   . THR C 3 108 ? 94.059  132.498 151.781 1.00 109.60 ? 108 THR L O   1 
ATOM   7928  C CB  . THR C 3 108 ? 91.607  131.548 150.491 1.00 134.92 ? 108 THR L CB  1 
ATOM   7929  O OG1 . THR C 3 108 ? 90.768  130.945 149.502 1.00 128.67 ? 108 THR L OG1 1 
ATOM   7930  C CG2 . THR C 3 108 ? 90.723  132.316 151.461 1.00 196.40 ? 108 THR L CG2 1 
ATOM   7931  N N   . LYS C 3 109 ? 93.349  134.491 150.986 1.00 92.76  ? 109 LYS L N   1 
ATOM   7932  C CA  . LYS C 3 109 ? 93.985  135.292 152.026 1.00 87.00  ? 109 LYS L CA  1 
ATOM   7933  C C   . LYS C 3 109 ? 93.010  135.387 153.192 1.00 78.46  ? 109 LYS L C   1 
ATOM   7934  O O   . LYS C 3 109 ? 91.989  136.080 153.118 1.00 132.10 ? 109 LYS L O   1 
ATOM   7935  C CB  . LYS C 3 109 ? 94.378  136.659 151.446 1.00 135.77 ? 109 LYS L CB  1 
ATOM   7936  C CG  . LYS C 3 109 ? 94.926  137.718 152.406 1.00 116.67 ? 109 LYS L CG  1 
ATOM   7937  C CD  . LYS C 3 109 ? 96.293  137.400 152.881 1.00 184.68 ? 109 LYS L CD  1 
ATOM   7938  C CE  . LYS C 3 109 ? 96.876  138.411 153.845 1.00 270.18 ? 109 LYS L CE  1 
ATOM   7939  N NZ  . LYS C 3 109 ? 97.977  137.815 154.651 1.00 274.49 ? 109 LYS L NZ  1 
ATOM   7940  N N   . LEU C 3 110 ? 93.305  134.693 154.283 1.00 79.68  ? 110 LEU L N   1 
ATOM   7941  C CA  . LEU C 3 110 ? 92.521  134.849 155.502 1.00 95.58  ? 110 LEU L CA  1 
ATOM   7942  C C   . LEU C 3 110 ? 93.042  136.089 156.211 1.00 101.98 ? 110 LEU L C   1 
ATOM   7943  O O   . LEU C 3 110 ? 94.236  136.285 156.281 1.00 167.53 ? 110 LEU L O   1 
ATOM   7944  C CB  . LEU C 3 110 ? 92.632  133.586 156.348 1.00 110.09 ? 110 LEU L CB  1 
ATOM   7945  C CG  . LEU C 3 110 ? 92.209  133.669 157.802 1.00 110.50 ? 110 LEU L CG  1 
ATOM   7946  C CD1 . LEU C 3 110 ? 90.768  134.008 157.897 1.00 160.77 ? 110 LEU L CD1 1 
ATOM   7947  C CD2 . LEU C 3 110 ? 92.428  132.316 158.447 1.00 110.71 ? 110 LEU L CD2 1 
ATOM   7948  N N   . GLU C 3 111 ? 92.131  136.947 156.659 1.00 127.32 ? 111 GLU L N   1 
ATOM   7949  C CA  . GLU C 3 111 ? 92.419  138.162 157.396 1.00 146.72 ? 111 GLU L CA  1 
ATOM   7950  C C   . GLU C 3 111 ? 91.596  138.131 158.677 1.00 122.95 ? 111 GLU L C   1 
ATOM   7951  O O   . GLU C 3 111 ? 90.531  137.523 158.729 1.00 183.19 ? 111 GLU L O   1 
ATOM   7952  C CB  . GLU C 3 111 ? 92.009  139.397 156.567 1.00 191.59 ? 111 GLU L CB  1 
ATOM   7953  C CG  . GLU C 3 111 ? 92.654  139.494 155.195 1.00 208.98 ? 111 GLU L CG  1 
ATOM   7954  C CD  . GLU C 3 111 ? 91.987  140.489 154.254 1.00 324.88 ? 111 GLU L CD  1 
ATOM   7955  O OE1 . GLU C 3 111 ? 91.578  141.574 154.729 1.00 370.08 ? 111 GLU L OE1 1 
ATOM   7956  O OE2 . GLU C 3 111 ? 91.880  140.187 153.042 1.00 395.67 ? 111 GLU L OE2 1 
ATOM   7957  N N   . ILE C 3 112 ? 92.064  138.839 159.702 1.00 128.40 ? 112 ILE L N   1 
ATOM   7958  C CA  . ILE C 3 112 ? 91.366  138.860 160.973 1.00 133.53 ? 112 ILE L CA  1 
ATOM   7959  C C   . ILE C 3 112 ? 90.617  140.190 161.145 1.00 156.49 ? 112 ILE L C   1 
ATOM   7960  O O   . ILE C 3 112 ? 91.109  141.255 160.764 1.00 204.33 ? 112 ILE L O   1 
ATOM   7961  C CB  . ILE C 3 112 ? 92.371  138.583 162.103 1.00 141.87 ? 112 ILE L CB  1 
ATOM   7962  C CG1 . ILE C 3 112 ? 93.110  137.257 161.907 1.00 159.11 ? 112 ILE L CG1 1 
ATOM   7963  C CG2 . ILE C 3 112 ? 91.706  138.636 163.465 1.00 161.15 ? 112 ILE L CG2 1 
ATOM   7964  C CD1 . ILE C 3 112 ? 92.252  136.047 161.869 1.00 146.22 ? 112 ILE L CD1 1 
ATOM   7965  N N   . LYS C 3 113 ? 89.420  140.095 161.742 1.00 161.25 ? 113 LYS L N   1 
ATOM   7966  C CA  . LYS C 3 113 ? 88.656  141.238 162.217 1.00 176.04 ? 113 LYS L CA  1 
ATOM   7967  C C   . LYS C 3 113 ? 88.775  141.369 163.740 1.00 163.77 ? 113 LYS L C   1 
ATOM   7968  O O   . LYS C 3 113 ? 88.621  140.377 164.463 1.00 172.63 ? 113 LYS L O   1 
ATOM   7969  C CB  . LYS C 3 113 ? 87.193  141.084 161.797 1.00 184.16 ? 113 LYS L CB  1 
ATOM   7970  C CG  . LYS C 3 113 ? 86.883  141.502 160.369 1.00 226.15 ? 113 LYS L CG  1 
ATOM   7971  C CD  . LYS C 3 113 ? 85.521  141.032 159.905 1.00 254.25 ? 113 LYS L CD  1 
ATOM   7972  C CE  . LYS C 3 113 ? 84.348  141.712 160.581 1.00 284.83 ? 113 LYS L CE  1 
ATOM   7973  N NZ  . LYS C 3 113 ? 83.093  140.954 160.359 1.00 302.20 ? 113 LYS L NZ  1 
ATOM   7974  N N   . ARG C 3 114 ? 89.028  142.601 164.205 1.00 172.40 ? 114 ARG L N   1 
ATOM   7975  C CA  . ARG C 3 114 ? 89.126  142.929 165.618 1.00 202.15 ? 114 ARG L CA  1 
ATOM   7976  C C   . ARG C 3 114 ? 88.444  144.272 165.901 1.00 240.59 ? 114 ARG L C   1 
ATOM   7977  O O   . ARG C 3 114 ? 88.046  144.989 164.982 1.00 235.30 ? 114 ARG L O   1 
ATOM   7978  C CB  . ARG C 3 114 ? 90.597  142.989 166.038 1.00 205.09 ? 114 ARG L CB  1 
ATOM   7979  C CG  . ARG C 3 114 ? 91.452  143.986 165.256 1.00 193.84 ? 114 ARG L CG  1 
ATOM   7980  C CD  . ARG C 3 114 ? 92.736  144.321 165.998 1.00 186.95 ? 114 ARG L CD  1 
ATOM   7981  N NE  . ARG C 3 114 ? 92.504  145.198 167.148 1.00 208.01 ? 114 ARG L NE  1 
ATOM   7982  C CZ  . ARG C 3 114 ? 93.167  145.196 168.310 1.00 220.01 ? 114 ARG L CZ  1 
ATOM   7983  N NH1 . ARG C 3 114 ? 92.829  146.058 169.260 1.00 245.42 ? 114 ARG L NH1 1 
ATOM   7984  N NH2 . ARG C 3 114 ? 94.165  144.352 168.529 1.00 224.48 ? 114 ARG L NH2 1 
ATOM   7985  N N   . ALA C 3 115 ? 88.323  144.597 167.198 1.00 260.24 ? 115 ALA L N   1 
ATOM   7986  C CA  . ALA C 3 115 ? 87.875  145.907 167.653 1.00 271.89 ? 115 ALA L CA  1 
ATOM   7987  C C   . ALA C 3 115 ? 88.816  146.993 167.134 1.00 247.64 ? 115 ALA L C   1 
ATOM   7988  O O   . ALA C 3 115 ? 90.029  146.882 167.299 1.00 279.92 ? 115 ALA L O   1 
ATOM   7989  C CB  . ALA C 3 115 ? 87.808  145.939 169.160 1.00 297.79 ? 115 ALA L CB  1 
ATOM   7990  N N   . ASP C 3 116 ? 88.243  148.034 166.510 1.00 223.35 ? 116 ASP L N   1 
ATOM   7991  C CA  . ASP C 3 116 ? 89.010  149.107 165.882 1.00 241.88 ? 116 ASP L CA  1 
ATOM   7992  C C   . ASP C 3 116 ? 89.883  149.819 166.925 1.00 250.59 ? 116 ASP L C   1 
ATOM   7993  O O   . ASP C 3 116 ? 89.501  149.917 168.092 1.00 302.26 ? 116 ASP L O   1 
ATOM   7994  C CB  . ASP C 3 116 ? 88.091  150.111 165.167 1.00 288.63 ? 116 ASP L CB  1 
ATOM   7995  C CG  . ASP C 3 116 ? 87.142  149.552 164.107 1.00 300.45 ? 116 ASP L CG  1 
ATOM   7996  O OD1 . ASP C 3 116 ? 86.977  148.310 164.027 1.00 296.12 ? 116 ASP L OD1 1 
ATOM   7997  O OD2 . ASP C 3 116 ? 86.558  150.370 163.367 1.00 299.40 ? 116 ASP L OD2 1 
ATOM   7998  N N   . ALA C 3 117 ? 91.057  150.317 166.500 1.00 218.29 ? 117 ALA L N   1 
ATOM   7999  C CA  . ALA C 3 117 ? 92.013  150.971 167.381 1.00 232.87 ? 117 ALA L CA  1 
ATOM   8000  C C   . ALA C 3 117 ? 92.813  152.049 166.645 1.00 214.91 ? 117 ALA L C   1 
ATOM   8001  O O   . ALA C 3 117 ? 93.219  151.843 165.508 1.00 199.77 ? 117 ALA L O   1 
ATOM   8002  C CB  . ALA C 3 117 ? 92.909  149.915 167.974 1.00 220.45 ? 117 ALA L CB  1 
ATOM   8003  N N   . ALA C 3 118 ? 93.040  153.189 167.310 1.00 215.51 ? 118 ALA L N   1 
ATOM   8004  C CA  . ALA C 3 118 ? 93.703  154.332 166.701 1.00 218.06 ? 118 ALA L CA  1 
ATOM   8005  C C   . ALA C 3 118 ? 95.215  154.118 166.705 1.00 198.25 ? 118 ALA L C   1 
ATOM   8006  O O   . ALA C 3 118 ? 95.745  153.486 167.622 1.00 196.33 ? 118 ALA L O   1 
ATOM   8007  C CB  . ALA C 3 118 ? 93.358  155.604 167.445 1.00 283.00 ? 118 ALA L CB  1 
ATOM   8008  N N   . PRO C 3 119 ? 95.957  154.649 165.699 1.00 183.07 ? 119 PRO L N   1 
ATOM   8009  C CA  . PRO C 3 119 ? 97.405  154.471 165.638 1.00 188.24 ? 119 PRO L CA  1 
ATOM   8010  C C   . PRO C 3 119 ? 98.149  155.245 166.729 1.00 181.90 ? 119 PRO L C   1 
ATOM   8011  O O   . PRO C 3 119 ? 97.833  156.390 167.012 1.00 167.02 ? 119 PRO L O   1 
ATOM   8012  C CB  . PRO C 3 119 ? 97.765  155.016 164.242 1.00 196.39 ? 119 PRO L CB  1 
ATOM   8013  C CG  . PRO C 3 119 ? 96.710  156.024 163.945 1.00 213.28 ? 119 PRO L CG  1 
ATOM   8014  C CD  . PRO C 3 119 ? 95.454  155.458 164.576 1.00 193.16 ? 119 PRO L CD  1 
ATOM   8015  N N   . THR C 3 120 ? 99.151  154.600 167.331 1.00 218.64 ? 120 THR L N   1 
ATOM   8016  C CA  . THR C 3 120 ? 100.255 155.317 167.952 1.00 234.82 ? 120 THR L CA  1 
ATOM   8017  C C   . THR C 3 120 ? 101.052 156.016 166.846 1.00 203.79 ? 120 THR L C   1 
ATOM   8018  O O   . THR C 3 120 ? 101.562 155.350 165.957 1.00 176.13 ? 120 THR L O   1 
ATOM   8019  C CB  . THR C 3 120 ? 101.142 154.362 168.759 1.00 264.16 ? 120 THR L CB  1 
ATOM   8020  O OG1 . THR C 3 120 ? 100.334 153.692 169.735 1.00 217.83 ? 120 THR L OG1 1 
ATOM   8021  C CG2 . THR C 3 120 ? 102.305 155.073 169.423 1.00 276.51 ? 120 THR L CG2 1 
ATOM   8022  N N   . VAL C 3 121 ? 101.152 157.348 166.886 1.00 192.18 ? 121 VAL L N   1 
ATOM   8023  C CA  . VAL C 3 121 ? 101.843 158.105 165.845 1.00 188.85 ? 121 VAL L CA  1 
ATOM   8024  C C   . VAL C 3 121 ? 103.124 158.693 166.438 1.00 193.26 ? 121 VAL L C   1 
ATOM   8025  O O   . VAL C 3 121 ? 103.090 159.281 167.523 1.00 259.48 ? 121 VAL L O   1 
ATOM   8026  C CB  . VAL C 3 121 ? 100.948 159.205 165.234 1.00 240.79 ? 121 VAL L CB  1 
ATOM   8027  C CG1 . VAL C 3 121 ? 101.701 160.058 164.213 1.00 196.34 ? 121 VAL L CG1 1 
ATOM   8028  C CG2 . VAL C 3 121 ? 99.658  158.630 164.635 1.00 223.06 ? 121 VAL L CG2 1 
ATOM   8029  N N   . SER C 3 122 ? 104.237 158.524 165.699 1.00 203.97 ? 122 SER L N   1 
ATOM   8030  C CA  . SER C 3 122 ? 105.552 159.037 166.055 1.00 224.03 ? 122 SER L CA  1 
ATOM   8031  C C   . SER C 3 122 ? 106.262 159.572 164.813 1.00 226.93 ? 122 SER L C   1 
ATOM   8032  O O   . SER C 3 122 ? 106.109 159.015 163.730 1.00 213.99 ? 122 SER L O   1 
ATOM   8033  C CB  . SER C 3 122 ? 106.379 157.969 166.719 1.00 228.62 ? 122 SER L CB  1 
ATOM   8034  O OG  . SER C 3 122 ? 105.766 157.526 167.921 1.00 219.66 ? 122 SER L OG  1 
ATOM   8035  N N   . ILE C 3 123 ? 107.045 160.649 164.984 1.00 222.42 ? 123 ILE L N   1 
ATOM   8036  C CA  . ILE C 3 123 ? 107.788 161.254 163.885 1.00 209.68 ? 123 ILE L CA  1 
ATOM   8037  C C   . ILE C 3 123 ? 109.251 161.424 164.296 1.00 221.99 ? 123 ILE L C   1 
ATOM   8038  O O   . ILE C 3 123 ? 109.541 161.797 165.433 1.00 206.76 ? 123 ILE L O   1 
ATOM   8039  C CB  . ILE C 3 123 ? 107.150 162.579 163.416 1.00 190.61 ? 123 ILE L CB  1 
ATOM   8040  C CG1 . ILE C 3 123 ? 107.880 163.115 162.184 1.00 202.42 ? 123 ILE L CG1 1 
ATOM   8041  C CG2 . ILE C 3 123 ? 107.084 163.631 164.527 1.00 243.39 ? 123 ILE L CG2 1 
ATOM   8042  C CD1 . ILE C 3 123 ? 107.146 164.202 161.471 1.00 232.08 ? 123 ILE L CD1 1 
ATOM   8043  N N   . PHE C 3 124 ? 110.150 161.155 163.334 1.00 226.93 ? 124 PHE L N   1 
ATOM   8044  C CA  . PHE C 3 124 ? 111.581 161.081 163.568 1.00 243.66 ? 124 PHE L CA  1 
ATOM   8045  C C   . PHE C 3 124 ? 112.294 162.116 162.706 1.00 232.32 ? 124 PHE L C   1 
ATOM   8046  O O   . PHE C 3 124 ? 112.270 162.001 161.487 1.00 170.68 ? 124 PHE L O   1 
ATOM   8047  C CB  . PHE C 3 124 ? 112.076 159.664 163.281 1.00 240.42 ? 124 PHE L CB  1 
ATOM   8048  C CG  . PHE C 3 124 ? 111.410 158.622 164.143 1.00 230.25 ? 124 PHE L CG  1 
ATOM   8049  C CD1 . PHE C 3 124 ? 110.189 158.076 163.771 1.00 199.76 ? 124 PHE L CD1 1 
ATOM   8050  C CD2 . PHE C 3 124 ? 112.004 158.199 165.328 1.00 241.09 ? 124 PHE L CD2 1 
ATOM   8051  C CE1 . PHE C 3 124 ? 109.573 157.130 164.575 1.00 257.85 ? 124 PHE L CE1 1 
ATOM   8052  C CE2 . PHE C 3 124 ? 111.394 157.244 166.127 1.00 231.59 ? 124 PHE L CE2 1 
ATOM   8053  C CZ  . PHE C 3 124 ? 110.178 156.718 165.751 1.00 274.45 ? 124 PHE L CZ  1 
ATOM   8054  N N   . PRO C 3 125 ? 112.953 163.143 163.303 1.00 270.20 ? 125 PRO L N   1 
ATOM   8055  C CA  . PRO C 3 125 ? 113.816 164.049 162.541 1.00 279.66 ? 125 PRO L CA  1 
ATOM   8056  C C   . PRO C 3 125 ? 114.942 163.310 161.810 1.00 278.47 ? 125 PRO L C   1 
ATOM   8057  O O   . PRO C 3 125 ? 115.420 162.297 162.324 1.00 287.12 ? 125 PRO L O   1 
ATOM   8058  C CB  . PRO C 3 125 ? 114.413 164.986 163.605 1.00 293.57 ? 125 PRO L CB  1 
ATOM   8059  C CG  . PRO C 3 125 ? 113.452 164.905 164.776 1.00 284.79 ? 125 PRO L CG  1 
ATOM   8060  C CD  . PRO C 3 125 ? 112.897 163.500 164.732 1.00 291.72 ? 125 PRO L CD  1 
ATOM   8061  N N   . PRO C 3 126 ? 115.397 163.780 160.613 1.00 253.80 ? 126 PRO L N   1 
ATOM   8062  C CA  . PRO C 3 126 ? 116.513 163.163 159.880 1.00 214.56 ? 126 PRO L CA  1 
ATOM   8063  C C   . PRO C 3 126 ? 117.763 162.835 160.706 1.00 261.76 ? 126 PRO L C   1 
ATOM   8064  O O   . PRO C 3 126 ? 118.160 163.600 161.595 1.00 302.25 ? 126 PRO L O   1 
ATOM   8065  C CB  . PRO C 3 126 ? 116.874 164.235 158.838 1.00 240.83 ? 126 PRO L CB  1 
ATOM   8066  C CG  . PRO C 3 126 ? 115.556 164.912 158.555 1.00 252.78 ? 126 PRO L CG  1 
ATOM   8067  C CD  . PRO C 3 126 ? 114.837 164.935 159.889 1.00 269.32 ? 126 PRO L CD  1 
ATOM   8068  N N   . SER C 3 127 ? 118.375 161.685 160.387 1.00 278.64 ? 127 SER L N   1 
ATOM   8069  C CA  . SER C 3 127 ? 119.568 161.187 161.060 1.00 295.24 ? 127 SER L CA  1 
ATOM   8070  C C   . SER C 3 127 ? 120.748 162.115 160.779 1.00 310.03 ? 127 SER L C   1 
ATOM   8071  O O   . SER C 3 127 ? 120.972 162.461 159.620 1.00 331.89 ? 127 SER L O   1 
ATOM   8072  C CB  . SER C 3 127 ? 119.882 159.773 160.615 1.00 301.10 ? 127 SER L CB  1 
ATOM   8073  O OG  . SER C 3 127 ? 118.713 158.971 160.540 1.00 286.35 ? 127 SER L OG  1 
ATOM   8074  N N   . SER C 3 128 ? 121.502 162.513 161.818 1.00 319.98 ? 128 SER L N   1 
ATOM   8075  C CA  . SER C 3 128 ? 122.591 163.476 161.659 1.00 328.48 ? 128 SER L CA  1 
ATOM   8076  C C   . SER C 3 128 ? 123.663 162.977 160.680 1.00 304.85 ? 128 SER L C   1 
ATOM   8077  O O   . SER C 3 128 ? 124.324 163.802 160.047 1.00 241.85 ? 128 SER L O   1 
ATOM   8078  C CB  . SER C 3 128 ? 123.195 163.864 162.998 1.00 321.38 ? 128 SER L CB  1 
ATOM   8079  O OG  . SER C 3 128 ? 123.704 162.736 163.690 1.00 315.97 ? 128 SER L OG  1 
ATOM   8080  N N   . GLU C 3 129 ? 123.818 161.645 160.551 1.00 288.29 ? 129 GLU L N   1 
ATOM   8081  C CA  . GLU C 3 129 ? 124.712 161.030 159.571 1.00 290.00 ? 129 GLU L CA  1 
ATOM   8082  C C   . GLU C 3 129 ? 124.199 161.227 158.142 1.00 251.28 ? 129 GLU L C   1 
ATOM   8083  O O   . GLU C 3 129 ? 125.002 161.461 157.239 1.00 317.75 ? 129 GLU L O   1 
ATOM   8084  C CB  . GLU C 3 129 ? 124.903 159.529 159.827 1.00 297.08 ? 129 GLU L CB  1 
ATOM   8085  C CG  . GLU C 3 129 ? 125.370 159.192 161.236 1.00 338.83 ? 129 GLU L CG  1 
ATOM   8086  C CD  . GLU C 3 129 ? 124.273 158.791 162.209 1.00 416.97 ? 129 GLU L CD  1 
ATOM   8087  O OE1 . GLU C 3 129 ? 123.155 159.351 162.111 1.00 453.55 ? 129 GLU L OE1 1 
ATOM   8088  O OE2 . GLU C 3 129 ? 124.538 157.925 163.061 1.00 471.15 ? 129 GLU L OE2 1 
ATOM   8089  N N   . GLN C 3 130 ? 122.878 161.128 157.932 1.00 230.06 ? 130 GLN L N   1 
ATOM   8090  C CA  . GLN C 3 130 ? 122.287 161.252 156.604 1.00 264.23 ? 130 GLN L CA  1 
ATOM   8091  C C   . GLN C 3 130 ? 122.538 162.645 156.020 1.00 267.24 ? 130 GLN L C   1 
ATOM   8092  O O   . GLN C 3 130 ? 122.716 162.770 154.814 1.00 317.76 ? 130 GLN L O   1 
ATOM   8093  C CB  . GLN C 3 130 ? 120.782 160.965 156.603 1.00 263.69 ? 130 GLN L CB  1 
ATOM   8094  C CG  . GLN C 3 130 ? 120.269 160.633 155.208 1.00 266.79 ? 130 GLN L CG  1 
ATOM   8095  C CD  . GLN C 3 130 ? 118.773 160.495 155.095 1.00 321.87 ? 130 GLN L CD  1 
ATOM   8096  O OE1 . GLN C 3 130 ? 118.028 160.709 156.051 1.00 345.25 ? 130 GLN L OE1 1 
ATOM   8097  N NE2 . GLN C 3 130 ? 118.327 160.131 153.903 1.00 317.15 ? 130 GLN L NE2 1 
ATOM   8098  N N   . LEU C 3 131 ? 122.583 163.676 156.871 1.00 260.10 ? 131 LEU L N   1 
ATOM   8099  C CA  . LEU C 3 131 ? 122.803 165.056 156.451 1.00 324.13 ? 131 LEU L CA  1 
ATOM   8100  C C   . LEU C 3 131 ? 124.160 165.250 155.753 1.00 344.53 ? 131 LEU L C   1 
ATOM   8101  O O   . LEU C 3 131 ? 124.353 166.265 155.089 1.00 327.76 ? 131 LEU L O   1 
ATOM   8102  C CB  . LEU C 3 131 ? 122.693 165.964 157.686 1.00 368.13 ? 131 LEU L CB  1 
ATOM   8103  C CG  . LEU C 3 131 ? 121.363 165.947 158.450 1.00 349.47 ? 131 LEU L CG  1 
ATOM   8104  C CD1 . LEU C 3 131 ? 121.429 166.866 159.663 1.00 351.71 ? 131 LEU L CD1 1 
ATOM   8105  C CD2 . LEU C 3 131 ? 120.188 166.334 157.561 1.00 322.37 ? 131 LEU L CD2 1 
ATOM   8106  N N   . THR C 3 132 ? 125.105 164.298 155.885 1.00 336.48 ? 132 THR L N   1 
ATOM   8107  C CA  . THR C 3 132 ? 126.349 164.313 155.120 1.00 348.07 ? 132 THR L CA  1 
ATOM   8108  C C   . THR C 3 132 ? 126.134 164.051 153.620 1.00 349.43 ? 132 THR L C   1 
ATOM   8109  O O   . THR C 3 132 ? 126.984 164.443 152.822 1.00 391.52 ? 132 THR L O   1 
ATOM   8110  C CB  . THR C 3 132 ? 127.368 163.298 155.669 1.00 351.88 ? 132 THR L CB  1 
ATOM   8111  O OG1 . THR C 3 132 ? 126.887 161.968 155.455 1.00 316.50 ? 132 THR L OG1 1 
ATOM   8112  C CG2 . THR C 3 132 ? 127.681 163.506 157.139 1.00 333.55 ? 132 THR L CG2 1 
ATOM   8113  N N   . SER C 3 133 ? 125.016 163.405 153.237 1.00 326.06 ? 133 SER L N   1 
ATOM   8114  C CA  . SER C 3 133 ? 124.799 162.860 151.899 1.00 331.45 ? 133 SER L CA  1 
ATOM   8115  C C   . SER C 3 133 ? 124.352 163.892 150.859 1.00 342.20 ? 133 SER L C   1 
ATOM   8116  O O   . SER C 3 133 ? 124.271 163.548 149.680 1.00 320.61 ? 133 SER L O   1 
ATOM   8117  C CB  . SER C 3 133 ? 123.770 161.755 151.959 1.00 372.71 ? 133 SER L CB  1 
ATOM   8118  O OG  . SER C 3 133 ? 122.470 162.280 152.226 1.00 432.71 ? 133 SER L OG  1 
ATOM   8119  N N   . GLY C 3 134 ? 124.037 165.132 151.271 1.00 374.09 ? 134 GLY L N   1 
ATOM   8120  C CA  . GLY C 3 134 ? 123.350 166.081 150.409 1.00 396.18 ? 134 GLY L CA  1 
ATOM   8121  C C   . GLY C 3 134 ? 121.837 165.855 150.326 1.00 356.19 ? 134 GLY L C   1 
ATOM   8122  O O   . GLY C 3 134 ? 121.152 166.653 149.686 1.00 367.08 ? 134 GLY L O   1 
ATOM   8123  N N   . GLY C 3 135 ? 121.320 164.791 150.970 1.00 332.63 ? 135 GLY L N   1 
ATOM   8124  C CA  . GLY C 3 135 ? 119.890 164.565 151.128 1.00 339.86 ? 135 GLY L CA  1 
ATOM   8125  C C   . GLY C 3 135 ? 119.504 164.332 152.590 1.00 340.99 ? 135 GLY L C   1 
ATOM   8126  O O   . GLY C 3 135 ? 120.367 164.247 153.465 1.00 290.83 ? 135 GLY L O   1 
ATOM   8127  N N   . ALA C 3 136 ? 118.187 164.241 152.824 1.00 325.80 ? 136 ALA L N   1 
ATOM   8128  C CA  . ALA C 3 136 ? 117.609 163.946 154.129 1.00 295.71 ? 136 ALA L CA  1 
ATOM   8129  C C   . ALA C 3 136 ? 116.260 163.254 153.944 1.00 296.95 ? 136 ALA L C   1 
ATOM   8130  O O   . ALA C 3 136 ? 115.543 163.563 152.992 1.00 285.28 ? 136 ALA L O   1 
ATOM   8131  C CB  . ALA C 3 136 ? 117.456 165.207 154.921 1.00 290.54 ? 136 ALA L CB  1 
ATOM   8132  N N   . SER C 3 137 ? 115.929 162.315 154.847 1.00 308.07 ? 137 SER L N   1 
ATOM   8133  C CA  . SER C 3 137 ? 114.653 161.611 154.805 1.00 272.31 ? 137 SER L CA  1 
ATOM   8134  C C   . SER C 3 137 ? 113.965 161.734 156.160 1.00 240.69 ? 137 SER L C   1 
ATOM   8135  O O   . SER C 3 137 ? 114.521 161.295 157.158 1.00 214.24 ? 137 SER L O   1 
ATOM   8136  C CB  . SER C 3 137 ? 114.799 160.153 154.421 1.00 265.38 ? 137 SER L CB  1 
ATOM   8137  O OG  . SER C 3 137 ? 115.355 159.999 153.124 1.00 264.99 ? 137 SER L OG  1 
ATOM   8138  N N   . VAL C 3 138 ? 112.752 162.308 156.160 1.00 223.64 ? 138 VAL L N   1 
ATOM   8139  C CA  . VAL C 3 138 ? 111.902 162.423 157.335 1.00 227.33 ? 138 VAL L CA  1 
ATOM   8140  C C   . VAL C 3 138 ? 110.939 161.236 157.344 1.00 238.31 ? 138 VAL L C   1 
ATOM   8141  O O   . VAL C 3 138 ? 110.395 160.903 156.297 1.00 188.20 ? 138 VAL L O   1 
ATOM   8142  C CB  . VAL C 3 138 ? 111.129 163.751 157.326 1.00 229.80 ? 138 VAL L CB  1 
ATOM   8143  C CG1 . VAL C 3 138 ? 110.445 163.991 158.661 1.00 197.22 ? 138 VAL L CG1 1 
ATOM   8144  C CG2 . VAL C 3 138 ? 112.002 164.944 156.956 1.00 306.04 ? 138 VAL L CG2 1 
ATOM   8145  N N   . VAL C 3 139 ? 110.721 160.618 158.522 1.00 233.92 ? 139 VAL L N   1 
ATOM   8146  C CA  . VAL C 3 139 ? 109.960 159.374 158.639 1.00 186.21 ? 139 VAL L CA  1 
ATOM   8147  C C   . VAL C 3 139 ? 108.933 159.459 159.770 1.00 198.22 ? 139 VAL L C   1 
ATOM   8148  O O   . VAL C 3 139 ? 109.236 159.893 160.872 1.00 172.69 ? 139 VAL L O   1 
ATOM   8149  C CB  . VAL C 3 139 ? 110.879 158.157 158.833 1.00 182.97 ? 139 VAL L CB  1 
ATOM   8150  C CG1 . VAL C 3 139 ? 110.109 156.898 159.245 1.00 205.36 ? 139 VAL L CG1 1 
ATOM   8151  C CG2 . VAL C 3 139 ? 111.693 157.906 157.575 1.00 234.06 ? 139 VAL L CG2 1 
ATOM   8152  N N   . CYS C 3 140 ? 107.706 159.020 159.446 1.00 211.55 ? 140 CYS L N   1 
ATOM   8153  C CA  . CYS C 3 140 ? 106.569 158.998 160.350 1.00 208.68 ? 140 CYS L CA  1 
ATOM   8154  C C   . CYS C 3 140 ? 106.059 157.563 160.451 1.00 178.40 ? 140 CYS L C   1 
ATOM   8155  O O   . CYS C 3 140 ? 105.718 156.969 159.434 1.00 134.53 ? 140 CYS L O   1 
ATOM   8156  C CB  . CYS C 3 140 ? 105.498 159.944 159.816 1.00 247.33 ? 140 CYS L CB  1 
ATOM   8157  S SG  . CYS C 3 140 ? 104.086 160.198 160.911 1.00 244.26 ? 140 CYS L SG  1 
ATOM   8158  N N   . PHE C 3 141 ? 106.011 157.033 161.680 1.00 194.24 ? 141 PHE L N   1 
ATOM   8159  C CA  . PHE C 3 141 ? 105.512 155.696 161.951 1.00 190.81 ? 141 PHE L CA  1 
ATOM   8160  C C   . PHE C 3 141 ? 104.147 155.744 162.622 1.00 183.01 ? 141 PHE L C   1 
ATOM   8161  O O   . PHE C 3 141 ? 103.964 156.468 163.590 1.00 176.65 ? 141 PHE L O   1 
ATOM   8162  C CB  . PHE C 3 141 ? 106.460 154.961 162.892 1.00 160.39 ? 141 PHE L CB  1 
ATOM   8163  C CG  . PHE C 3 141 ? 107.746 154.450 162.302 1.00 160.00 ? 141 PHE L CG  1 
ATOM   8164  C CD1 . PHE C 3 141 ? 107.961 154.318 160.938 1.00 159.04 ? 141 PHE L CD1 1 
ATOM   8165  C CD2 . PHE C 3 141 ? 108.773 154.085 163.152 1.00 166.55 ? 141 PHE L CD2 1 
ATOM   8166  C CE1 . PHE C 3 141 ? 109.176 153.830 160.461 1.00 188.18 ? 141 PHE L CE1 1 
ATOM   8167  C CE2 . PHE C 3 141 ? 109.984 153.612 162.667 1.00 202.08 ? 141 PHE L CE2 1 
ATOM   8168  C CZ  . PHE C 3 141 ? 110.186 153.465 161.318 1.00 169.88 ? 141 PHE L CZ  1 
ATOM   8169  N N   . LEU C 3 142 ? 103.221 154.942 162.088 1.00 197.16 ? 142 LEU L N   1 
ATOM   8170  C CA  . LEU C 3 142 ? 101.883 154.758 162.620 1.00 176.02 ? 142 LEU L CA  1 
ATOM   8171  C C   . LEU C 3 142 ? 101.791 153.291 163.057 1.00 176.51 ? 142 LEU L C   1 
ATOM   8172  O O   . LEU C 3 142 ? 101.823 152.404 162.213 1.00 135.25 ? 142 LEU L O   1 
ATOM   8173  C CB  . LEU C 3 142 ? 100.861 155.091 161.523 1.00 149.89 ? 142 LEU L CB  1 
ATOM   8174  C CG  . LEU C 3 142 ? 101.161 156.295 160.641 1.00 172.01 ? 142 LEU L CG  1 
ATOM   8175  C CD1 . LEU C 3 142 ? 100.205 156.305 159.473 1.00 180.74 ? 142 LEU L CD1 1 
ATOM   8176  C CD2 . LEU C 3 142 ? 101.104 157.596 161.422 1.00 233.08 ? 142 LEU L CD2 1 
ATOM   8177  N N   . ASN C 3 143 ? 101.696 153.032 164.365 1.00 168.52 ? 143 ASN L N   1 
ATOM   8178  C CA  . ASN C 3 143 ? 101.804 151.677 164.881 1.00 157.31 ? 143 ASN L CA  1 
ATOM   8179  C C   . ASN C 3 143 ? 100.478 151.200 165.487 1.00 160.27 ? 143 ASN L C   1 
ATOM   8180  O O   . ASN C 3 143 ? 99.795  151.955 166.183 1.00 232.81 ? 143 ASN L O   1 
ATOM   8181  C CB  . ASN C 3 143 ? 102.922 151.555 165.923 1.00 187.35 ? 143 ASN L CB  1 
ATOM   8182  C CG  . ASN C 3 143 ? 104.289 151.834 165.349 1.00 202.11 ? 143 ASN L CG  1 
ATOM   8183  O OD1 . ASN C 3 143 ? 104.650 152.990 165.141 1.00 218.21 ? 143 ASN L OD1 1 
ATOM   8184  N ND2 . ASN C 3 143 ? 105.054 150.783 165.098 1.00 220.86 ? 143 ASN L ND2 1 
ATOM   8185  N N   . ASN C 3 144 ? 100.154 149.928 165.212 1.00 163.12 ? 144 ASN L N   1 
ATOM   8186  C CA  . ASN C 3 144 ? 99.185  149.109 165.935 1.00 168.60 ? 144 ASN L CA  1 
ATOM   8187  C C   . ASN C 3 144 ? 97.774  149.682 165.855 1.00 164.33 ? 144 ASN L C   1 
ATOM   8188  O O   . ASN C 3 144 ? 97.233  150.145 166.864 1.00 221.05 ? 144 ASN L O   1 
ATOM   8189  C CB  . ASN C 3 144 ? 99.552  148.890 167.410 1.00 188.17 ? 144 ASN L CB  1 
ATOM   8190  C CG  . ASN C 3 144 ? 100.870 148.177 167.582 1.00 251.27 ? 144 ASN L CG  1 
ATOM   8191  O OD1 . ASN C 3 144 ? 101.826 148.789 168.051 1.00 228.55 ? 144 ASN L OD1 1 
ATOM   8192  N ND2 . ASN C 3 144 ? 100.917 146.910 167.193 1.00 307.67 ? 144 ASN L ND2 1 
ATOM   8193  N N   . PHE C 3 145 ? 97.182  149.637 164.655 1.00 146.93 ? 145 PHE L N   1 
ATOM   8194  C CA  . PHE C 3 145 ? 95.829  150.117 164.437 1.00 157.73 ? 145 PHE L CA  1 
ATOM   8195  C C   . PHE C 3 145 ? 94.996  149.088 163.675 1.00 147.30 ? 145 PHE L C   1 
ATOM   8196  O O   . PHE C 3 145 ? 95.520  148.121 163.145 1.00 159.16 ? 145 PHE L O   1 
ATOM   8197  C CB  . PHE C 3 145 ? 95.905  151.472 163.726 1.00 177.65 ? 145 PHE L CB  1 
ATOM   8198  C CG  . PHE C 3 145 ? 96.540  151.464 162.366 1.00 146.37 ? 145 PHE L CG  1 
ATOM   8199  C CD1 . PHE C 3 145 ? 95.799  151.107 161.239 1.00 185.88 ? 145 PHE L CD1 1 
ATOM   8200  C CD2 . PHE C 3 145 ? 97.863  151.819 162.217 1.00 132.59 ? 145 PHE L CD2 1 
ATOM   8201  C CE1 . PHE C 3 145 ? 96.373  151.097 159.977 1.00 194.55 ? 145 PHE L CE1 1 
ATOM   8202  C CE2 . PHE C 3 145 ? 98.427  151.809 160.949 1.00 209.20 ? 145 PHE L CE2 1 
ATOM   8203  C CZ  . PHE C 3 145 ? 97.689  151.450 159.834 1.00 214.49 ? 145 PHE L CZ  1 
ATOM   8204  N N   . TYR C 3 146 ? 93.681  149.321 163.625 1.00 181.41 ? 146 TYR L N   1 
ATOM   8205  C CA  . TYR C 3 146 ? 92.756  148.518 162.844 1.00 177.01 ? 146 TYR L CA  1 
ATOM   8206  C C   . TYR C 3 146 ? 91.544  149.376 162.496 1.00 147.46 ? 146 TYR L C   1 
ATOM   8207  O O   . TYR C 3 146 ? 91.102  150.117 163.358 1.00 140.67 ? 146 TYR L O   1 
ATOM   8208  C CB  . TYR C 3 146 ? 92.280  147.258 163.592 1.00 156.31 ? 146 TYR L CB  1 
ATOM   8209  C CG  . TYR C 3 146 ? 91.514  146.323 162.661 1.00 140.71 ? 146 TYR L CG  1 
ATOM   8210  C CD1 . TYR C 3 146 ? 92.168  145.387 161.866 1.00 178.31 ? 146 TYR L CD1 1 
ATOM   8211  C CD2 . TYR C 3 146 ? 90.146  146.413 162.527 1.00 155.36 ? 146 TYR L CD2 1 
ATOM   8212  C CE1 . TYR C 3 146 ? 91.479  144.549 160.997 1.00 229.32 ? 146 TYR L CE1 1 
ATOM   8213  C CE2 . TYR C 3 146 ? 89.445  145.587 161.658 1.00 204.99 ? 146 TYR L CE2 1 
ATOM   8214  C CZ  . TYR C 3 146 ? 90.107  144.648 160.882 1.00 219.82 ? 146 TYR L CZ  1 
ATOM   8215  O OH  . TYR C 3 146 ? 89.424  143.818 160.029 1.00 252.20 ? 146 TYR L OH  1 
ATOM   8216  N N   . PRO C 3 147 ? 90.918  149.303 161.300 1.00 140.19 ? 147 PRO L N   1 
ATOM   8217  C CA  . PRO C 3 147 ? 91.352  148.496 160.158 1.00 157.30 ? 147 PRO L CA  1 
ATOM   8218  C C   . PRO C 3 147 ? 92.443  149.188 159.349 1.00 173.00 ? 147 PRO L C   1 
ATOM   8219  O O   . PRO C 3 147 ? 92.886  150.283 159.698 1.00 159.57 ? 147 PRO L O   1 
ATOM   8220  C CB  . PRO C 3 147 ? 90.044  148.368 159.355 1.00 199.10 ? 147 PRO L CB  1 
ATOM   8221  C CG  . PRO C 3 147 ? 89.384  149.726 159.550 1.00 222.41 ? 147 PRO L CG  1 
ATOM   8222  C CD  . PRO C 3 147 ? 89.673  150.032 161.003 1.00 194.85 ? 147 PRO L CD  1 
ATOM   8223  N N   . LYS C 3 148 ? 92.835  148.500 158.263 1.00 181.93 ? 148 LYS L N   1 
ATOM   8224  C CA  . LYS C 3 148 ? 93.923  148.860 157.367 1.00 185.07 ? 148 LYS L CA  1 
ATOM   8225  C C   . LYS C 3 148 ? 93.786  150.275 156.773 1.00 196.52 ? 148 LYS L C   1 
ATOM   8226  O O   . LYS C 3 148 ? 94.794  150.932 156.564 1.00 240.23 ? 148 LYS L O   1 
ATOM   8227  C CB  . LYS C 3 148 ? 94.013  147.807 156.250 1.00 167.49 ? 148 LYS L CB  1 
ATOM   8228  C CG  . LYS C 3 148 ? 95.205  147.986 155.324 1.00 229.88 ? 148 LYS L CG  1 
ATOM   8229  C CD  . LYS C 3 148 ? 95.389  146.913 154.258 1.00 242.35 ? 148 LYS L CD  1 
ATOM   8230  C CE  . LYS C 3 148 ? 96.480  147.278 153.265 1.00 253.00 ? 148 LYS L CE  1 
ATOM   8231  N NZ  . LYS C 3 148 ? 97.257  146.126 152.725 1.00 263.30 ? 148 LYS L NZ  1 
ATOM   8232  N N   . ASP C 3 149 ? 92.575  150.755 156.469 1.00 224.98 ? 149 ASP L N   1 
ATOM   8233  C CA  . ASP C 3 149 ? 92.400  152.024 155.768 1.00 250.71 ? 149 ASP L CA  1 
ATOM   8234  C C   . ASP C 3 149 ? 92.853  153.201 156.634 1.00 231.59 ? 149 ASP L C   1 
ATOM   8235  O O   . ASP C 3 149 ? 92.390  153.355 157.772 1.00 205.65 ? 149 ASP L O   1 
ATOM   8236  C CB  . ASP C 3 149 ? 90.944  152.249 155.331 1.00 340.94 ? 149 ASP L CB  1 
ATOM   8237  C CG  . ASP C 3 149 ? 90.504  151.509 154.075 1.00 400.27 ? 149 ASP L CG  1 
ATOM   8238  O OD1 . ASP C 3 149 ? 91.366  150.896 153.403 1.00 410.22 ? 149 ASP L OD1 1 
ATOM   8239  O OD2 . ASP C 3 149 ? 89.291  151.546 153.777 1.00 428.67 ? 149 ASP L OD2 1 
ATOM   8240  N N   . ILE C 3 150 ? 93.756  154.026 156.061 1.00 201.59 ? 150 ILE L N   1 
ATOM   8241  C CA  . ILE C 3 150 ? 94.338  155.198 156.713 1.00 169.60 ? 150 ILE L CA  1 
ATOM   8242  C C   . ILE C 3 150 ? 94.855  156.159 155.640 1.00 224.25 ? 150 ILE L C   1 
ATOM   8243  O O   . ILE C 3 150 ? 95.069  155.738 154.500 1.00 265.18 ? 150 ILE L O   1 
ATOM   8244  C CB  . ILE C 3 150 ? 95.438  154.728 157.678 1.00 155.46 ? 150 ILE L CB  1 
ATOM   8245  C CG1 . ILE C 3 150 ? 95.898  155.801 158.648 1.00 151.33 ? 150 ILE L CG1 1 
ATOM   8246  C CG2 . ILE C 3 150 ? 96.646  154.150 156.955 1.00 238.00 ? 150 ILE L CG2 1 
ATOM   8247  C CD1 . ILE C 3 150 ? 96.749  155.210 159.780 1.00 197.96 ? 150 ILE L CD1 1 
ATOM   8248  N N   . ASN C 3 151 ? 95.041  157.447 155.983 1.00 230.98 ? 151 ASN L N   1 
ATOM   8249  C CA  . ASN C 3 151 ? 95.786  158.357 155.116 1.00 263.80 ? 151 ASN L CA  1 
ATOM   8250  C C   . ASN C 3 151 ? 96.613  159.331 155.961 1.00 236.79 ? 151 ASN L C   1 
ATOM   8251  O O   . ASN C 3 151 ? 96.337  159.556 157.144 1.00 186.14 ? 151 ASN L O   1 
ATOM   8252  C CB  . ASN C 3 151 ? 94.884  159.043 154.068 1.00 316.60 ? 151 ASN L CB  1 
ATOM   8253  C CG  . ASN C 3 151 ? 93.812  159.981 154.603 1.00 380.54 ? 151 ASN L CG  1 
ATOM   8254  O OD1 . ASN C 3 151 ? 94.085  160.827 155.454 1.00 435.16 ? 151 ASN L OD1 1 
ATOM   8255  N ND2 . ASN C 3 151 ? 92.587  159.855 154.106 1.00 385.09 ? 151 ASN L ND2 1 
ATOM   8256  N N   . VAL C 3 152 ? 97.637  159.904 155.310 1.00 232.74 ? 152 VAL L N   1 
ATOM   8257  C CA  . VAL C 3 152 ? 98.617  160.764 155.951 1.00 233.89 ? 152 VAL L CA  1 
ATOM   8258  C C   . VAL C 3 152 ? 98.742  162.068 155.165 1.00 288.93 ? 152 VAL L C   1 
ATOM   8259  O O   . VAL C 3 152 ? 98.835  162.049 153.935 1.00 292.63 ? 152 VAL L O   1 
ATOM   8260  C CB  . VAL C 3 152 ? 99.982  160.065 156.036 1.00 232.95 ? 152 VAL L CB  1 
ATOM   8261  C CG1 . VAL C 3 152 ? 101.009 160.904 156.783 1.00 248.73 ? 152 VAL L CG1 1 
ATOM   8262  C CG2 . VAL C 3 152 ? 99.855  158.691 156.660 1.00 255.06 ? 152 VAL L CG2 1 
ATOM   8263  N N   . LYS C 3 153 ? 98.754  163.188 155.907 1.00 283.90 ? 153 LYS L N   1 
ATOM   8264  C CA  . LYS C 3 153 ? 99.120  164.499 155.396 1.00 280.55 ? 153 LYS L CA  1 
ATOM   8265  C C   . LYS C 3 153 ? 100.502 164.879 155.933 1.00 208.11 ? 153 LYS L C   1 
ATOM   8266  O O   . LYS C 3 153 ? 100.755 164.814 157.136 1.00 152.33 ? 153 LYS L O   1 
ATOM   8267  C CB  . LYS C 3 153 ? 98.069  165.539 155.804 1.00 357.09 ? 153 LYS L CB  1 
ATOM   8268  C CG  . LYS C 3 153 ? 96.975  165.813 154.780 1.00 387.05 ? 153 LYS L CG  1 
ATOM   8269  C CD  . LYS C 3 153 ? 96.102  164.624 154.453 1.00 396.48 ? 153 LYS L CD  1 
ATOM   8270  C CE  . LYS C 3 153 ? 95.006  164.956 153.462 1.00 401.87 ? 153 LYS L CE  1 
ATOM   8271  N NZ  . LYS C 3 153 ? 95.546  165.305 152.125 1.00 421.81 ? 153 LYS L NZ  1 
ATOM   8272  N N   . TRP C 3 154 ? 101.398 165.279 155.029 1.00 184.96 ? 154 TRP L N   1 
ATOM   8273  C CA  . TRP C 3 154 ? 102.636 165.929 155.413 1.00 223.63 ? 154 TRP L CA  1 
ATOM   8274  C C   . TRP C 3 154 ? 102.491 167.442 155.243 1.00 297.13 ? 154 TRP L C   1 
ATOM   8275  O O   . TRP C 3 154 ? 102.073 167.905 154.179 1.00 339.65 ? 154 TRP L O   1 
ATOM   8276  C CB  . TRP C 3 154 ? 103.788 165.381 154.564 1.00 260.05 ? 154 TRP L CB  1 
ATOM   8277  C CG  . TRP C 3 154 ? 104.281 164.041 155.038 1.00 201.55 ? 154 TRP L CG  1 
ATOM   8278  C CD1 . TRP C 3 154 ? 103.859 162.830 154.593 1.00 203.92 ? 154 TRP L CD1 1 
ATOM   8279  C CD2 . TRP C 3 154 ? 105.289 163.783 156.040 1.00 188.38 ? 154 TRP L CD2 1 
ATOM   8280  N NE1 . TRP C 3 154 ? 104.530 161.833 155.241 1.00 238.45 ? 154 TRP L NE1 1 
ATOM   8281  C CE2 . TRP C 3 154 ? 105.414 162.382 156.132 1.00 210.35 ? 154 TRP L CE2 1 
ATOM   8282  C CE3 . TRP C 3 154 ? 106.094 164.581 156.859 1.00 207.29 ? 154 TRP L CE3 1 
ATOM   8283  C CZ2 . TRP C 3 154 ? 106.308 161.767 157.009 1.00 255.91 ? 154 TRP L CZ2 1 
ATOM   8284  C CZ3 . TRP C 3 154 ? 106.980 163.980 157.719 1.00 206.97 ? 154 TRP L CZ3 1 
ATOM   8285  C CH2 . TRP C 3 154 ? 107.078 162.591 157.799 1.00 265.04 ? 154 TRP L CH2 1 
ATOM   8286  N N   . LYS C 3 155 ? 102.841 168.192 156.300 1.00 260.04 ? 155 LYS L N   1 
ATOM   8287  C CA  . LYS C 3 155 ? 102.884 169.645 156.269 1.00 270.39 ? 155 LYS L CA  1 
ATOM   8288  C C   . LYS C 3 155 ? 104.303 170.122 156.593 1.00 288.73 ? 155 LYS L C   1 
ATOM   8289  O O   . LYS C 3 155 ? 104.980 169.570 157.455 1.00 230.44 ? 155 LYS L O   1 
ATOM   8290  C CB  . LYS C 3 155 ? 101.843 170.228 157.231 1.00 279.51 ? 155 LYS L CB  1 
ATOM   8291  C CG  . LYS C 3 155 ? 100.536 170.686 156.591 1.00 311.01 ? 155 LYS L CG  1 
ATOM   8292  C CD  . LYS C 3 155 ? 99.651  169.565 156.084 1.00 332.45 ? 155 LYS L CD  1 
ATOM   8293  C CE  . LYS C 3 155 ? 98.304  170.046 155.581 1.00 366.73 ? 155 LYS L CE  1 
ATOM   8294  N NZ  . LYS C 3 155 ? 97.376  170.384 156.687 1.00 384.47 ? 155 LYS L NZ  1 
ATOM   8295  N N   . ILE C 3 156 ? 104.734 171.169 155.882 1.00 335.86 ? 156 ILE L N   1 
ATOM   8296  C CA  . ILE C 3 156 ? 106.092 171.695 155.935 1.00 344.49 ? 156 ILE L CA  1 
ATOM   8297  C C   . ILE C 3 156 ? 105.965 173.226 155.963 1.00 393.60 ? 156 ILE L C   1 
ATOM   8298  O O   . ILE C 3 156 ? 105.541 173.837 154.979 1.00 463.08 ? 156 ILE L O   1 
ATOM   8299  C CB  . ILE C 3 156 ? 106.942 171.106 154.775 1.00 304.16 ? 156 ILE L CB  1 
ATOM   8300  C CG1 . ILE C 3 156 ? 108.301 171.800 154.634 1.00 372.93 ? 156 ILE L CG1 1 
ATOM   8301  C CG2 . ILE C 3 156 ? 106.203 171.103 153.441 1.00 271.40 ? 156 ILE L CG2 1 
ATOM   8302  C CD1 . ILE C 3 156 ? 109.255 171.118 153.674 1.00 372.26 ? 156 ILE L CD1 1 
ATOM   8303  N N   . ASP C 3 157 ? 106.302 173.830 157.119 1.00 344.40 ? 157 ASP L N   1 
ATOM   8304  C CA  . ASP C 3 157 ? 105.979 175.215 157.457 1.00 354.83 ? 157 ASP L CA  1 
ATOM   8305  C C   . ASP C 3 157 ? 104.509 175.541 157.149 1.00 329.81 ? 157 ASP L C   1 
ATOM   8306  O O   . ASP C 3 157 ? 104.205 176.658 156.727 1.00 401.72 ? 157 ASP L O   1 
ATOM   8307  C CB  . ASP C 3 157 ? 106.981 176.160 156.769 1.00 394.77 ? 157 ASP L CB  1 
ATOM   8308  C CG  . ASP C 3 157 ? 108.412 176.096 157.289 1.00 347.21 ? 157 ASP L CG  1 
ATOM   8309  O OD1 . ASP C 3 157 ? 108.648 175.438 158.316 1.00 305.62 ? 157 ASP L OD1 1 
ATOM   8310  O OD2 . ASP C 3 157 ? 109.294 176.713 156.664 1.00 281.99 ? 157 ASP L OD2 1 
ATOM   8311  N N   . GLY C 3 158 ? 103.594 174.577 157.354 1.00 271.03 ? 158 GLY L N   1 
ATOM   8312  C CA  . GLY C 3 158 ? 102.179 174.764 157.042 1.00 296.28 ? 158 GLY L CA  1 
ATOM   8313  C C   . GLY C 3 158 ? 101.754 174.408 155.608 1.00 329.88 ? 158 GLY L C   1 
ATOM   8314  O O   . GLY C 3 158 ? 100.565 174.162 155.383 1.00 226.56 ? 158 GLY L O   1 
ATOM   8315  N N   . SER C 3 159 ? 102.691 174.384 154.642 1.00 382.05 ? 159 SER L N   1 
ATOM   8316  C CA  . SER C 3 159 ? 102.389 174.008 153.264 1.00 390.02 ? 159 SER L CA  1 
ATOM   8317  C C   . SER C 3 159 ? 102.178 172.494 153.158 1.00 344.06 ? 159 SER L C   1 
ATOM   8318  O O   . SER C 3 159 ? 102.949 171.735 153.735 1.00 326.43 ? 159 SER L O   1 
ATOM   8319  C CB  . SER C 3 159 ? 103.488 174.480 152.336 1.00 412.31 ? 159 SER L CB  1 
ATOM   8320  O OG  . SER C 3 159 ? 103.162 174.214 150.980 1.00 436.58 ? 159 SER L OG  1 
ATOM   8321  N N   . GLU C 3 160 ? 101.148 172.057 152.417 1.00 295.80 ? 160 GLU L N   1 
ATOM   8322  C CA  . GLU C 3 160 ? 100.852 170.640 152.233 1.00 303.27 ? 160 GLU L CA  1 
ATOM   8323  C C   . GLU C 3 160 ? 101.777 170.034 151.170 1.00 345.80 ? 160 GLU L C   1 
ATOM   8324  O O   . GLU C 3 160 ? 101.924 170.597 150.081 1.00 378.73 ? 160 GLU L O   1 
ATOM   8325  C CB  . GLU C 3 160 ? 99.385  170.456 151.831 1.00 346.28 ? 160 GLU L CB  1 
ATOM   8326  C CG  . GLU C 3 160 ? 98.934  169.002 151.784 1.00 389.91 ? 160 GLU L CG  1 
ATOM   8327  C CD  . GLU C 3 160 ? 97.452  168.773 151.542 1.00 421.74 ? 160 GLU L CD  1 
ATOM   8328  O OE1 . GLU C 3 160 ? 96.751  169.732 151.152 1.00 427.18 ? 160 GLU L OE1 1 
ATOM   8329  O OE2 . GLU C 3 160 ? 96.999  167.628 151.749 1.00 458.58 ? 160 GLU L OE2 1 
ATOM   8330  N N   . ARG C 3 161 ? 102.383 168.872 151.485 1.00 329.62 ? 161 ARG L N   1 
ATOM   8331  C CA  . ARG C 3 161 ? 103.355 168.212 150.620 1.00 301.56 ? 161 ARG L CA  1 
ATOM   8332  C C   . ARG C 3 161 ? 102.766 166.926 150.024 1.00 263.57 ? 161 ARG L C   1 
ATOM   8333  O O   . ARG C 3 161 ? 102.251 166.070 150.754 1.00 248.44 ? 161 ARG L O   1 
ATOM   8334  C CB  . ARG C 3 161 ? 104.622 167.911 151.425 1.00 278.72 ? 161 ARG L CB  1 
ATOM   8335  C CG  . ARG C 3 161 ? 105.777 167.324 150.624 1.00 298.65 ? 161 ARG L CG  1 
ATOM   8336  C CD  . ARG C 3 161 ? 106.268 168.137 149.436 1.00 275.28 ? 161 ARG L CD  1 
ATOM   8337  N NE  . ARG C 3 161 ? 107.450 167.479 148.872 1.00 322.57 ? 161 ARG L NE  1 
ATOM   8338  C CZ  . ARG C 3 161 ? 108.619 168.057 148.570 1.00 344.64 ? 161 ARG L CZ  1 
ATOM   8339  N NH1 . ARG C 3 161 ? 109.628 167.315 148.138 1.00 333.56 ? 161 ARG L NH1 1 
ATOM   8340  N NH2 . ARG C 3 161 ? 108.797 169.364 148.702 1.00 348.01 ? 161 ARG L NH2 1 
ATOM   8341  N N   . GLN C 3 162 ? 102.860 166.797 148.688 1.00 208.68 ? 162 GLN L N   1 
ATOM   8342  C CA  . GLN C 3 162 ? 102.321 165.650 147.955 1.00 253.05 ? 162 GLN L CA  1 
ATOM   8343  C C   . GLN C 3 162 ? 103.296 165.080 146.905 1.00 261.48 ? 162 GLN L C   1 
ATOM   8344  O O   . GLN C 3 162 ? 103.028 163.994 146.372 1.00 224.82 ? 162 GLN L O   1 
ATOM   8345  C CB  . GLN C 3 162 ? 100.963 166.030 147.351 1.00 305.21 ? 162 GLN L CB  1 
ATOM   8346  C CG  . GLN C 3 162 ? 101.008 167.182 146.345 1.00 401.32 ? 162 GLN L CG  1 
ATOM   8347  C CD  . GLN C 3 162 ? 99.708  167.948 146.204 1.00 438.40 ? 162 GLN L CD  1 
ATOM   8348  O OE1 . GLN C 3 162 ? 98.701  167.651 146.846 1.00 421.11 ? 162 GLN L OE1 1 
ATOM   8349  N NE2 . GLN C 3 162 ? 99.724  168.960 145.349 1.00 462.41 ? 162 GLN L NE2 1 
ATOM   8350  N N   . ASN C 3 163 ? 104.411 165.777 146.603 1.00 255.45 ? 163 ASN L N   1 
ATOM   8351  C CA  . ASN C 3 163 ? 105.547 165.209 145.883 1.00 314.64 ? 163 ASN L CA  1 
ATOM   8352  C C   . ASN C 3 163 ? 106.472 164.447 146.837 1.00 327.80 ? 163 ASN L C   1 
ATOM   8353  O O   . ASN C 3 163 ? 106.678 164.886 147.969 1.00 319.58 ? 163 ASN L O   1 
ATOM   8354  C CB  . ASN C 3 163 ? 106.368 166.297 145.180 1.00 364.41 ? 163 ASN L CB  1 
ATOM   8355  C CG  . ASN C 3 163 ? 105.602 167.100 144.147 1.00 417.46 ? 163 ASN L CG  1 
ATOM   8356  O OD1 . ASN C 3 163 ? 104.612 166.637 143.585 1.00 475.22 ? 163 ASN L OD1 1 
ATOM   8357  N ND2 . ASN C 3 163 ? 106.062 168.312 143.878 1.00 418.10 ? 163 ASN L ND2 1 
ATOM   8358  N N   . GLY C 3 164 ? 107.035 163.316 146.371 1.00 340.56 ? 164 GLY L N   1 
ATOM   8359  C CA  . GLY C 3 164 ? 108.114 162.617 147.064 1.00 329.92 ? 164 GLY L CA  1 
ATOM   8360  C C   . GLY C 3 164 ? 107.720 162.017 148.417 1.00 297.50 ? 164 GLY L C   1 
ATOM   8361  O O   . GLY C 3 164 ? 108.570 161.920 149.299 1.00 239.86 ? 164 GLY L O   1 
ATOM   8362  N N   . VAL C 3 165 ? 106.441 161.619 148.558 1.00 294.14 ? 165 VAL L N   1 
ATOM   8363  C CA  . VAL C 3 165 ? 105.916 160.923 149.730 1.00 267.01 ? 165 VAL L CA  1 
ATOM   8364  C C   . VAL C 3 165 ? 105.647 159.459 149.357 1.00 272.20 ? 165 VAL L C   1 
ATOM   8365  O O   . VAL C 3 165 ? 105.038 159.184 148.322 1.00 239.60 ? 165 VAL L O   1 
ATOM   8366  C CB  . VAL C 3 165 ? 104.649 161.623 150.279 1.00 256.87 ? 165 VAL L CB  1 
ATOM   8367  C CG1 . VAL C 3 165 ? 103.830 160.768 151.238 1.00 210.71 ? 165 VAL L CG1 1 
ATOM   8368  C CG2 . VAL C 3 165 ? 105.003 162.949 150.936 1.00 224.17 ? 165 VAL L CG2 1 
ATOM   8369  N N   . LEU C 3 166 ? 106.078 158.548 150.244 1.00 251.39 ? 166 LEU L N   1 
ATOM   8370  C CA  . LEU C 3 166 ? 105.937 157.109 150.079 1.00 216.94 ? 166 LEU L CA  1 
ATOM   8371  C C   . LEU C 3 166 ? 105.346 156.496 151.346 1.00 210.40 ? 166 LEU L C   1 
ATOM   8372  O O   . LEU C 3 166 ? 105.570 157.017 152.437 1.00 194.41 ? 166 LEU L O   1 
ATOM   8373  C CB  . LEU C 3 166 ? 107.323 156.529 149.808 1.00 198.30 ? 166 LEU L CB  1 
ATOM   8374  C CG  . LEU C 3 166 ? 107.963 156.958 148.495 1.00 247.64 ? 166 LEU L CG  1 
ATOM   8375  C CD1 . LEU C 3 166 ? 109.409 156.473 148.421 1.00 248.04 ? 166 LEU L CD1 1 
ATOM   8376  C CD2 . LEU C 3 166 ? 107.157 156.432 147.314 1.00 253.97 ? 166 LEU L CD2 1 
ATOM   8377  N N   . ASN C 3 167 ? 104.613 155.387 151.163 1.00 200.01 ? 167 ASN L N   1 
ATOM   8378  C CA  . ASN C 3 167 ? 103.960 154.677 152.249 1.00 178.19 ? 167 ASN L CA  1 
ATOM   8379  C C   . ASN C 3 167 ? 104.186 153.172 152.118 1.00 205.10 ? 167 ASN L C   1 
ATOM   8380  O O   . ASN C 3 167 ? 104.268 152.646 151.000 1.00 214.61 ? 167 ASN L O   1 
ATOM   8381  C CB  . ASN C 3 167 ? 102.458 154.934 152.259 1.00 193.27 ? 167 ASN L CB  1 
ATOM   8382  C CG  . ASN C 3 167 ? 102.099 156.391 152.459 1.00 214.83 ? 167 ASN L CG  1 
ATOM   8383  O OD1 . ASN C 3 167 ? 102.709 157.078 153.274 1.00 135.45 ? 167 ASN L OD1 1 
ATOM   8384  N ND2 . ASN C 3 167 ? 101.106 156.875 151.731 1.00 255.97 ? 167 ASN L ND2 1 
ATOM   8385  N N   . SER C 3 168 ? 104.281 152.485 153.269 1.00 163.22 ? 168 SER L N   1 
ATOM   8386  C CA  . SER C 3 168 ? 104.271 151.029 153.283 1.00 186.54 ? 168 SER L CA  1 
ATOM   8387  C C   . SER C 3 168 ? 103.576 150.506 154.544 1.00 194.16 ? 168 SER L C   1 
ATOM   8388  O O   . SER C 3 168 ? 103.924 150.875 155.661 1.00 137.67 ? 168 SER L O   1 
ATOM   8389  C CB  . SER C 3 168 ? 105.661 150.490 153.163 1.00 241.16 ? 168 SER L CB  1 
ATOM   8390  O OG  . SER C 3 168 ? 105.643 149.068 153.155 1.00 239.39 ? 168 SER L OG  1 
ATOM   8391  N N   . TRP C 3 169 ? 102.584 149.630 154.337 1.00 186.27 ? 169 TRP L N   1 
ATOM   8392  C CA  . TRP C 3 169 ? 101.866 148.953 155.403 1.00 148.22 ? 169 TRP L CA  1 
ATOM   8393  C C   . TRP C 3 169 ? 102.530 147.639 155.719 1.00 135.39 ? 169 TRP L C   1 
ATOM   8394  O O   . TRP C 3 169 ? 102.958 146.973 154.762 1.00 156.45 ? 169 TRP L O   1 
ATOM   8395  C CB  . TRP C 3 169 ? 100.457 148.570 154.945 1.00 194.26 ? 169 TRP L CB  1 
ATOM   8396  C CG  . TRP C 3 169 ? 99.458  149.690 154.908 1.00 189.35 ? 169 TRP L CG  1 
ATOM   8397  C CD1 . TRP C 3 169 ? 98.471  149.865 155.824 1.00 173.63 ? 169 TRP L CD1 1 
ATOM   8398  C CD2 . TRP C 3 169 ? 99.328  150.752 153.941 1.00 179.74 ? 169 TRP L CD2 1 
ATOM   8399  N NE1 . TRP C 3 169 ? 97.727  150.953 155.492 1.00 188.49 ? 169 TRP L NE1 1 
ATOM   8400  C CE2 . TRP C 3 169 ? 98.231  151.528 154.351 1.00 175.56 ? 169 TRP L CE2 1 
ATOM   8401  C CE3 . TRP C 3 169 ? 100.026 151.131 152.788 1.00 232.00 ? 169 TRP L CE3 1 
ATOM   8402  C CZ2 . TRP C 3 169 ? 97.816  152.657 153.642 1.00 236.37 ? 169 TRP L CZ2 1 
ATOM   8403  C CZ3 . TRP C 3 169 ? 99.621  152.250 152.091 1.00 241.08 ? 169 TRP L CZ3 1 
ATOM   8404  C CH2 . TRP C 3 169 ? 98.526  153.001 152.512 1.00 241.59 ? 169 TRP L CH2 1 
ATOM   8405  N N   . THR C 3 170 ? 102.555 147.263 157.005 1.00 105.57 ? 170 THR L N   1 
ATOM   8406  C CA  . THR C 3 170 ? 102.889 145.876 157.315 1.00 146.52 ? 170 THR L CA  1 
ATOM   8407  C C   . THR C 3 170 ? 101.736 144.949 156.947 1.00 146.97 ? 170 THR L C   1 
ATOM   8408  O O   . THR C 3 170 ? 100.595 145.391 156.882 1.00 240.54 ? 170 THR L O   1 
ATOM   8409  C CB  . THR C 3 170 ? 103.269 145.627 158.779 1.00 152.36 ? 170 THR L CB  1 
ATOM   8410  O OG1 . THR C 3 170 ? 102.084 145.727 159.568 1.00 98.22  ? 170 THR L OG1 1 
ATOM   8411  C CG2 . THR C 3 170 ? 104.369 146.550 159.252 1.00 181.18 ? 170 THR L CG2 1 
ATOM   8412  N N   . ASP C 3 171 ? 102.058 143.669 156.721 1.00 157.45 ? 171 ASP L N   1 
ATOM   8413  C CA  . ASP C 3 171 ? 101.095 142.588 156.888 1.00 182.64 ? 171 ASP L CA  1 
ATOM   8414  C C   . ASP C 3 171 ? 100.589 142.609 158.335 1.00 158.90 ? 171 ASP L C   1 
ATOM   8415  O O   . ASP C 3 171 ? 101.258 143.122 159.236 1.00 165.97 ? 171 ASP L O   1 
ATOM   8416  C CB  . ASP C 3 171 ? 101.707 141.238 156.484 1.00 251.21 ? 171 ASP L CB  1 
ATOM   8417  C CG  . ASP C 3 171 ? 102.133 141.159 155.025 1.00 322.46 ? 171 ASP L CG  1 
ATOM   8418  O OD1 . ASP C 3 171 ? 101.939 142.168 154.302 1.00 331.18 ? 171 ASP L OD1 1 
ATOM   8419  O OD2 . ASP C 3 171 ? 102.654 140.093 154.620 1.00 410.11 ? 171 ASP L OD2 1 
ATOM   8420  N N   . GLN C 3 172 ? 99.398  142.048 158.554 1.00 134.61 ? 172 GLN L N   1 
ATOM   8421  C CA  . GLN C 3 172 ? 98.715  142.152 159.838 1.00 159.05 ? 172 GLN L CA  1 
ATOM   8422  C C   . GLN C 3 172 ? 99.430  141.289 160.892 1.00 142.45 ? 172 GLN L C   1 
ATOM   8423  O O   . GLN C 3 172 ? 99.790  140.149 160.615 1.00 158.55 ? 172 GLN L O   1 
ATOM   8424  C CB  . GLN C 3 172 ? 97.266  141.745 159.572 1.00 162.70 ? 172 GLN L CB  1 
ATOM   8425  C CG  . GLN C 3 172 ? 96.293  142.017 160.703 1.00 149.22 ? 172 GLN L CG  1 
ATOM   8426  C CD  . GLN C 3 172 ? 94.881  141.797 160.220 1.00 191.25 ? 172 GLN L CD  1 
ATOM   8427  O OE1 . GLN C 3 172 ? 94.653  141.506 159.042 1.00 161.50 ? 172 GLN L OE1 1 
ATOM   8428  N NE2 . GLN C 3 172 ? 93.909  141.962 161.112 1.00 260.34 ? 172 GLN L NE2 1 
ATOM   8429  N N   . ASP C 3 173 ? 99.661  141.820 162.100 1.00 154.98 ? 173 ASP L N   1 
ATOM   8430  C CA  . ASP C 3 173 ? 100.538 141.186 163.081 1.00 182.74 ? 173 ASP L CA  1 
ATOM   8431  C C   . ASP C 3 173 ? 99.829  139.997 163.737 1.00 148.75 ? 173 ASP L C   1 
ATOM   8432  O O   . ASP C 3 173 ? 98.805  140.175 164.375 1.00 206.60 ? 173 ASP L O   1 
ATOM   8433  C CB  . ASP C 3 173 ? 101.018 142.216 164.124 1.00 268.81 ? 173 ASP L CB  1 
ATOM   8434  C CG  . ASP C 3 173 ? 101.761 141.693 165.350 1.00 340.70 ? 173 ASP L CG  1 
ATOM   8435  O OD1 . ASP C 3 173 ? 102.010 140.463 165.437 1.00 403.54 ? 173 ASP L OD1 1 
ATOM   8436  O OD2 . ASP C 3 173 ? 102.096 142.531 166.225 1.00 329.84 ? 173 ASP L OD2 1 
ATOM   8437  N N   . SER C 3 174 ? 100.401 138.790 163.647 1.00 171.08 ? 174 SER L N   1 
ATOM   8438  C CA  . SER C 3 174 ? 99.784  137.569 164.173 1.00 212.09 ? 174 SER L CA  1 
ATOM   8439  C C   . SER C 3 174 ? 99.586  137.514 165.701 1.00 177.16 ? 174 SER L C   1 
ATOM   8440  O O   . SER C 3 174 ? 98.814  136.671 166.163 1.00 216.71 ? 174 SER L O   1 
ATOM   8441  C CB  . SER C 3 174 ? 100.571 136.362 163.715 1.00 252.16 ? 174 SER L CB  1 
ATOM   8442  O OG  . SER C 3 174 ? 101.937 136.515 164.065 1.00 282.73 ? 174 SER L OG  1 
ATOM   8443  N N   . LYS C 3 175 ? 100.239 138.373 166.498 1.00 193.47 ? 175 LYS L N   1 
ATOM   8444  C CA  . LYS C 3 175 ? 100.032 138.377 167.945 1.00 219.49 ? 175 LYS L CA  1 
ATOM   8445  C C   . LYS C 3 175 ? 98.795  139.183 168.359 1.00 212.02 ? 175 LYS L C   1 
ATOM   8446  O O   . LYS C 3 175 ? 98.162  138.851 169.363 1.00 256.33 ? 175 LYS L O   1 
ATOM   8447  C CB  . LYS C 3 175 ? 101.255 138.961 168.658 1.00 316.07 ? 175 LYS L CB  1 
ATOM   8448  C CG  . LYS C 3 175 ? 102.533 138.137 168.557 1.00 381.89 ? 175 LYS L CG  1 
ATOM   8449  C CD  . LYS C 3 175 ? 103.771 138.823 169.129 1.00 435.62 ? 175 LYS L CD  1 
ATOM   8450  C CE  . LYS C 3 175 ? 104.154 140.137 168.469 1.00 452.21 ? 175 LYS L CE  1 
ATOM   8451  N NZ  . LYS C 3 175 ? 104.326 140.012 167.001 1.00 438.38 ? 175 LYS L NZ  1 
ATOM   8452  N N   . ASP C 3 176 ? 98.467  140.243 167.604 1.00 202.99 ? 176 ASP L N   1 
ATOM   8453  C CA  . ASP C 3 176 ? 97.498  141.256 168.012 1.00 219.81 ? 176 ASP L CA  1 
ATOM   8454  C C   . ASP C 3 176 ? 96.520  141.661 166.896 1.00 162.62 ? 176 ASP L C   1 
ATOM   8455  O O   . ASP C 3 176 ? 95.612  142.446 167.141 1.00 152.48 ? 176 ASP L O   1 
ATOM   8456  C CB  . ASP C 3 176 ? 98.281  142.464 168.545 1.00 236.97 ? 176 ASP L CB  1 
ATOM   8457  C CG  . ASP C 3 176 ? 97.550  143.376 169.528 1.00 327.13 ? 176 ASP L CG  1 
ATOM   8458  O OD1 . ASP C 3 176 ? 96.391  143.081 169.895 1.00 415.58 ? 176 ASP L OD1 1 
ATOM   8459  O OD2 . ASP C 3 176 ? 98.162  144.391 169.929 1.00 318.40 ? 176 ASP L OD2 1 
ATOM   8460  N N   . SER C 3 177 ? 96.711  141.139 165.678 1.00 171.86 ? 177 SER L N   1 
ATOM   8461  C CA  . SER C 3 177 ? 95.885  141.382 164.508 1.00 154.32 ? 177 SER L CA  1 
ATOM   8462  C C   . SER C 3 177 ? 95.781  142.867 164.118 1.00 144.85 ? 177 SER L C   1 
ATOM   8463  O O   . SER C 3 177 ? 94.822  143.240 163.441 1.00 152.97 ? 177 SER L O   1 
ATOM   8464  C CB  . SER C 3 177 ? 94.563  140.737 164.715 1.00 173.72 ? 177 SER L CB  1 
ATOM   8465  O OG  . SER C 3 177 ? 94.738  139.353 164.982 1.00 196.66 ? 177 SER L OG  1 
ATOM   8466  N N   . THR C 3 178 ? 96.774  143.700 164.502 1.00 146.62 ? 178 THR L N   1 
ATOM   8467  C CA  . THR C 3 178 ? 96.847  145.097 164.100 1.00 151.69 ? 178 THR L CA  1 
ATOM   8468  C C   . THR C 3 178 ? 97.731  145.283 162.868 1.00 133.85 ? 178 THR L C   1 
ATOM   8469  O O   . THR C 3 178 ? 98.680  144.532 162.654 1.00 207.25 ? 178 THR L O   1 
ATOM   8470  C CB  . THR C 3 178 ? 97.412  146.001 165.203 1.00 156.78 ? 178 THR L CB  1 
ATOM   8471  O OG1 . THR C 3 178 ? 98.744  145.593 165.534 1.00 185.12 ? 178 THR L OG1 1 
ATOM   8472  C CG2 . THR C 3 178 ? 96.540  146.011 166.441 1.00 169.38 ? 178 THR L CG2 1 
ATOM   8473  N N   . TYR C 3 179 ? 97.405  146.305 162.072 1.00 115.28 ? 179 TYR L N   1 
ATOM   8474  C CA  . TYR C 3 179 ? 98.313  146.817 161.067 1.00 119.33 ? 179 TYR L CA  1 
ATOM   8475  C C   . TYR C 3 179 ? 99.250  147.839 161.696 1.00 123.09 ? 179 TYR L C   1 
ATOM   8476  O O   . TYR C 3 179 ? 98.995  148.342 162.783 1.00 162.71 ? 179 TYR L O   1 
ATOM   8477  C CB  . TYR C 3 179 ? 97.516  147.447 159.926 1.00 121.93 ? 179 TYR L CB  1 
ATOM   8478  C CG  . TYR C 3 179 ? 96.710  146.424 159.146 1.00 130.66 ? 179 TYR L CG  1 
ATOM   8479  C CD1 . TYR C 3 179 ? 95.497  145.968 159.601 1.00 121.97 ? 179 TYR L CD1 1 
ATOM   8480  C CD2 . TYR C 3 179 ? 97.178  145.905 157.946 1.00 188.96 ? 179 TYR L CD2 1 
ATOM   8481  C CE1 . TYR C 3 179 ? 94.764  145.043 158.874 1.00 194.14 ? 179 TYR L CE1 1 
ATOM   8482  C CE2 . TYR C 3 179 ? 96.457  144.974 157.212 1.00 191.29 ? 179 TYR L CE2 1 
ATOM   8483  C CZ  . TYR C 3 179 ? 95.240  144.539 157.676 1.00 203.63 ? 179 TYR L CZ  1 
ATOM   8484  O OH  . TYR C 3 179 ? 94.533  143.613 156.962 1.00 273.11 ? 179 TYR L OH  1 
ATOM   8485  N N   . SER C 3 180 ? 100.342 148.152 160.977 1.00 148.48 ? 180 SER L N   1 
ATOM   8486  C CA  . SER C 3 180 ? 101.183 149.332 161.192 1.00 138.51 ? 180 SER L CA  1 
ATOM   8487  C C   . SER C 3 180 ? 101.596 149.892 159.827 1.00 128.88 ? 180 SER L C   1 
ATOM   8488  O O   . SER C 3 180 ? 101.607 149.155 158.847 1.00 95.37  ? 180 SER L O   1 
ATOM   8489  C CB  . SER C 3 180 ? 102.378 149.012 162.033 1.00 139.58 ? 180 SER L CB  1 
ATOM   8490  O OG  . SER C 3 180 ? 102.004 148.637 163.355 1.00 166.69 ? 180 SER L OG  1 
ATOM   8491  N N   . MET C 3 181 ? 101.923 151.191 159.758 1.00 134.63 ? 181 MET L N   1 
ATOM   8492  C CA  . MET C 3 181 ? 102.302 151.812 158.493 1.00 149.36 ? 181 MET L CA  1 
ATOM   8493  C C   . MET C 3 181 ? 103.429 152.834 158.702 1.00 146.88 ? 181 MET L C   1 
ATOM   8494  O O   . MET C 3 181 ? 103.435 153.578 159.668 1.00 114.01 ? 181 MET L O   1 
ATOM   8495  C CB  . MET C 3 181 ? 101.127 152.515 157.812 1.00 138.87 ? 181 MET L CB  1 
ATOM   8496  C CG  . MET C 3 181 ? 101.398 152.748 156.347 1.00 192.25 ? 181 MET L CG  1 
ATOM   8497  S SD  . MET C 3 181 ? 100.249 153.920 155.595 1.00 183.13 ? 181 MET L SD  1 
ATOM   8498  C CE  . MET C 3 181 ? 101.295 155.370 155.761 1.00 279.85 ? 181 MET L CE  1 
ATOM   8499  N N   . SER C 3 182 ? 104.387 152.809 157.770 1.00 171.24 ? 182 SER L N   1 
ATOM   8500  C CA  . SER C 3 182 ? 105.462 153.770 157.678 1.00 154.47 ? 182 SER L CA  1 
ATOM   8501  C C   . SER C 3 182 ? 105.160 154.728 156.535 1.00 192.99 ? 182 SER L C   1 
ATOM   8502  O O   . SER C 3 182 ? 104.730 154.284 155.463 1.00 146.69 ? 182 SER L O   1 
ATOM   8503  C CB  . SER C 3 182 ? 106.751 153.069 157.445 1.00 180.58 ? 182 SER L CB  1 
ATOM   8504  O OG  . SER C 3 182 ? 107.785 153.968 157.062 1.00 285.57 ? 182 SER L OG  1 
ATOM   8505  N N   . SER C 3 183 ? 105.391 156.025 156.806 1.00 212.95 ? 183 SER L N   1 
ATOM   8506  C CA  . SER C 3 183 ? 105.350 157.071 155.801 1.00 207.84 ? 183 SER L CA  1 
ATOM   8507  C C   . SER C 3 183 ? 106.685 157.818 155.764 1.00 208.95 ? 183 SER L C   1 
ATOM   8508  O O   . SER C 3 183 ? 107.257 158.110 156.808 1.00 147.93 ? 183 SER L O   1 
ATOM   8509  C CB  . SER C 3 183 ? 104.208 157.993 156.064 1.00 191.78 ? 183 SER L CB  1 
ATOM   8510  O OG  . SER C 3 183 ? 104.022 158.843 154.951 1.00 218.24 ? 183 SER L OG  1 
ATOM   8511  N N   . THR C 3 184 ? 107.161 158.118 154.547 1.00 229.88 ? 184 THR L N   1 
ATOM   8512  C CA  . THR C 3 184 ? 108.501 158.638 154.316 1.00 234.10 ? 184 THR L CA  1 
ATOM   8513  C C   . THR C 3 184 ? 108.428 159.824 153.358 1.00 287.82 ? 184 THR L C   1 
ATOM   8514  O O   . THR C 3 184 ? 107.737 159.739 152.352 1.00 272.25 ? 184 THR L O   1 
ATOM   8515  C CB  . THR C 3 184 ? 109.425 157.568 153.718 1.00 274.69 ? 184 THR L CB  1 
ATOM   8516  O OG1 . THR C 3 184 ? 109.503 156.440 154.590 1.00 255.77 ? 184 THR L OG1 1 
ATOM   8517  C CG2 . THR C 3 184 ? 110.833 158.072 153.456 1.00 313.60 ? 184 THR L CG2 1 
ATOM   8518  N N   . LEU C 3 185 ? 109.154 160.905 153.679 1.00 280.65 ? 185 LEU L N   1 
ATOM   8519  C CA  . LEU C 3 185 ? 109.313 162.075 152.825 1.00 230.66 ? 185 LEU L CA  1 
ATOM   8520  C C   . LEU C 3 185 ? 110.810 162.329 152.631 1.00 238.23 ? 185 LEU L C   1 
ATOM   8521  O O   . LEU C 3 185 ? 111.520 162.483 153.621 1.00 228.34 ? 185 LEU L O   1 
ATOM   8522  C CB  . LEU C 3 185 ? 108.610 163.254 153.508 1.00 203.52 ? 185 LEU L CB  1 
ATOM   8523  C CG  . LEU C 3 185 ? 108.919 164.644 152.957 1.00 223.62 ? 185 LEU L CG  1 
ATOM   8524  C CD1 . LEU C 3 185 ? 108.550 164.738 151.473 1.00 238.71 ? 185 LEU L CD1 1 
ATOM   8525  C CD2 . LEU C 3 185 ? 108.225 165.696 153.800 1.00 248.29 ? 185 LEU L CD2 1 
ATOM   8526  N N   . THR C 3 186 ? 111.284 162.365 151.368 1.00 233.96 ? 186 THR L N   1 
ATOM   8527  C CA  . THR C 3 186 ? 112.698 162.571 151.063 1.00 268.05 ? 186 THR L CA  1 
ATOM   8528  C C   . THR C 3 186 ? 112.913 163.945 150.415 1.00 265.73 ? 186 THR L C   1 
ATOM   8529  O O   . THR C 3 186 ? 112.207 164.328 149.477 1.00 216.52 ? 186 THR L O   1 
ATOM   8530  C CB  . THR C 3 186 ? 113.276 161.429 150.215 1.00 298.40 ? 186 THR L CB  1 
ATOM   8531  O OG1 . THR C 3 186 ? 113.316 160.250 151.026 1.00 281.62 ? 186 THR L OG1 1 
ATOM   8532  C CG2 . THR C 3 186 ? 114.675 161.707 149.702 1.00 365.49 ? 186 THR L CG2 1 
ATOM   8533  N N   . LEU C 3 187 ? 113.929 164.655 150.944 1.00 261.16 ? 187 LEU L N   1 
ATOM   8534  C CA  . LEU C 3 187 ? 114.254 166.041 150.644 1.00 268.26 ? 187 LEU L CA  1 
ATOM   8535  C C   . LEU C 3 187 ? 115.732 166.144 150.248 1.00 318.13 ? 187 LEU L C   1 
ATOM   8536  O O   . LEU C 3 187 ? 116.548 165.314 150.657 1.00 326.23 ? 187 LEU L O   1 
ATOM   8537  C CB  . LEU C 3 187 ? 114.007 166.887 151.905 1.00 285.42 ? 187 LEU L CB  1 
ATOM   8538  C CG  . LEU C 3 187 ? 112.661 166.746 152.620 1.00 270.83 ? 187 LEU L CG  1 
ATOM   8539  C CD1 . LEU C 3 187 ? 112.640 167.547 153.921 1.00 271.43 ? 187 LEU L CD1 1 
ATOM   8540  C CD2 . LEU C 3 187 ? 111.519 167.178 151.708 1.00 263.01 ? 187 LEU L CD2 1 
ATOM   8541  N N   . THR C 3 188 ? 116.103 167.183 149.477 1.00 341.85 ? 188 THR L N   1 
ATOM   8542  C CA  . THR C 3 188 ? 117.508 167.586 149.390 1.00 317.05 ? 188 THR L CA  1 
ATOM   8543  C C   . THR C 3 188 ? 117.907 168.245 150.716 1.00 278.08 ? 188 THR L C   1 
ATOM   8544  O O   . THR C 3 188 ? 117.048 168.677 151.485 1.00 250.85 ? 188 THR L O   1 
ATOM   8545  C CB  . THR C 3 188 ? 117.826 168.506 148.195 1.00 336.10 ? 188 THR L CB  1 
ATOM   8546  O OG1 . THR C 3 188 ? 117.408 169.849 148.457 1.00 291.02 ? 188 THR L OG1 1 
ATOM   8547  C CG2 . THR C 3 188 ? 117.214 168.030 146.892 1.00 356.68 ? 188 THR L CG2 1 
ATOM   8548  N N   . LYS C 3 189 ? 119.213 168.332 150.997 1.00 269.34 ? 189 LYS L N   1 
ATOM   8549  C CA  . LYS C 3 189 ? 119.676 168.959 152.232 1.00 273.99 ? 189 LYS L CA  1 
ATOM   8550  C C   . LYS C 3 189 ? 119.231 170.425 152.274 1.00 272.94 ? 189 LYS L C   1 
ATOM   8551  O O   . LYS C 3 189 ? 118.752 170.877 153.311 1.00 286.10 ? 189 LYS L O   1 
ATOM   8552  C CB  . LYS C 3 189 ? 121.193 168.805 152.386 1.00 318.21 ? 189 LYS L CB  1 
ATOM   8553  C CG  . LYS C 3 189 ? 121.762 169.269 153.720 1.00 327.38 ? 189 LYS L CG  1 
ATOM   8554  C CD  . LYS C 3 189 ? 123.269 169.142 153.787 1.00 372.19 ? 189 LYS L CD  1 
ATOM   8555  C CE  . LYS C 3 189 ? 123.853 169.491 155.140 1.00 399.33 ? 189 LYS L CE  1 
ATOM   8556  N NZ  . LYS C 3 189 ? 123.947 170.956 155.353 1.00 417.79 ? 189 LYS L NZ  1 
ATOM   8557  N N   . ASP C 3 190 ? 119.372 171.146 151.150 1.00 302.04 ? 190 ASP L N   1 
ATOM   8558  C CA  . ASP C 3 190 ? 118.981 172.551 151.036 1.00 365.01 ? 190 ASP L CA  1 
ATOM   8559  C C   . ASP C 3 190 ? 117.457 172.745 151.106 1.00 380.90 ? 190 ASP L C   1 
ATOM   8560  O O   . ASP C 3 190 ? 116.992 173.823 151.489 1.00 440.21 ? 190 ASP L O   1 
ATOM   8561  C CB  . ASP C 3 190 ? 119.541 173.170 149.748 1.00 414.62 ? 190 ASP L CB  1 
ATOM   8562  C CG  . ASP C 3 190 ? 121.059 173.160 149.611 1.00 459.27 ? 190 ASP L CG  1 
ATOM   8563  O OD1 . ASP C 3 190 ? 121.753 172.867 150.610 1.00 466.02 ? 190 ASP L OD1 1 
ATOM   8564  O OD2 . ASP C 3 190 ? 121.543 173.446 148.494 1.00 479.58 ? 190 ASP L OD2 1 
ATOM   8565  N N   . GLU C 3 191 ? 116.682 171.713 150.731 1.00 310.16 ? 191 GLU L N   1 
ATOM   8566  C CA  . GLU C 3 191 ? 115.230 171.675 150.887 1.00 298.08 ? 191 GLU L CA  1 
ATOM   8567  C C   . GLU C 3 191 ? 114.830 171.441 152.353 1.00 256.85 ? 191 GLU L C   1 
ATOM   8568  O O   . GLU C 3 191 ? 113.822 171.982 152.802 1.00 211.34 ? 191 GLU L O   1 
ATOM   8569  C CB  . GLU C 3 191 ? 114.700 170.600 149.935 1.00 309.87 ? 191 GLU L CB  1 
ATOM   8570  C CG  . GLU C 3 191 ? 113.194 170.427 149.886 1.00 368.00 ? 191 GLU L CG  1 
ATOM   8571  C CD  . GLU C 3 191 ? 112.751 169.388 148.865 1.00 431.36 ? 191 GLU L CD  1 
ATOM   8572  O OE1 . GLU C 3 191 ? 113.587 168.539 148.458 1.00 462.35 ? 191 GLU L OE1 1 
ATOM   8573  O OE2 . GLU C 3 191 ? 111.573 169.432 148.469 1.00 448.38 ? 191 GLU L OE2 1 
ATOM   8574  N N   . TYR C 3 192 ? 115.608 170.637 153.097 1.00 244.21 ? 192 TYR L N   1 
ATOM   8575  C CA  . TYR C 3 192 ? 115.442 170.480 154.542 1.00 256.15 ? 192 TYR L CA  1 
ATOM   8576  C C   . TYR C 3 192 ? 115.969 171.705 155.320 1.00 301.36 ? 192 TYR L C   1 
ATOM   8577  O O   . TYR C 3 192 ? 115.563 171.930 156.465 1.00 341.23 ? 192 TYR L O   1 
ATOM   8578  C CB  . TYR C 3 192 ? 116.099 169.159 154.979 1.00 262.61 ? 192 TYR L CB  1 
ATOM   8579  C CG  . TYR C 3 192 ? 116.156 168.968 156.492 1.00 274.91 ? 192 TYR L CG  1 
ATOM   8580  C CD1 . TYR C 3 192 ? 114.985 168.909 157.246 1.00 194.24 ? 192 TYR L CD1 1 
ATOM   8581  C CD2 . TYR C 3 192 ? 117.373 168.865 157.175 1.00 331.46 ? 192 TYR L CD2 1 
ATOM   8582  C CE1 . TYR C 3 192 ? 115.027 168.748 158.629 1.00 248.36 ? 192 TYR L CE1 1 
ATOM   8583  C CE2 . TYR C 3 192 ? 117.423 168.709 158.558 1.00 312.41 ? 192 TYR L CE2 1 
ATOM   8584  C CZ  . TYR C 3 192 ? 116.246 168.654 159.294 1.00 278.25 ? 192 TYR L CZ  1 
ATOM   8585  O OH  . TYR C 3 192 ? 116.302 168.488 160.655 1.00 207.70 ? 192 TYR L OH  1 
ATOM   8586  N N   . GLU C 3 193 ? 116.877 172.501 154.725 1.00 318.25 ? 193 GLU L N   1 
ATOM   8587  C CA  . GLU C 3 193 ? 117.476 173.661 155.381 1.00 332.62 ? 193 GLU L CA  1 
ATOM   8588  C C   . GLU C 3 193 ? 116.524 174.860 155.383 1.00 317.72 ? 193 GLU L C   1 
ATOM   8589  O O   . GLU C 3 193 ? 116.408 175.541 156.405 1.00 268.59 ? 193 GLU L O   1 
ATOM   8590  C CB  . GLU C 3 193 ? 118.803 174.017 154.697 1.00 412.66 ? 193 GLU L CB  1 
ATOM   8591  C CG  . GLU C 3 193 ? 119.752 174.828 155.565 1.00 475.34 ? 193 GLU L CG  1 
ATOM   8592  C CD  . GLU C 3 193 ? 120.407 174.091 156.724 1.00 511.82 ? 193 GLU L CD  1 
ATOM   8593  O OE1 . GLU C 3 193 ? 120.197 172.864 156.866 1.00 490.63 ? 193 GLU L OE1 1 
ATOM   8594  O OE2 . GLU C 3 193 ? 121.135 174.751 157.495 1.00 560.40 ? 193 GLU L OE2 1 
ATOM   8595  N N   . ARG C 3 194 ? 115.860 175.105 154.240 1.00 343.02 ? 194 ARG L N   1 
ATOM   8596  C CA  . ARG C 3 194 ? 115.080 176.316 153.997 1.00 364.75 ? 194 ARG L CA  1 
ATOM   8597  C C   . ARG C 3 194 ? 113.756 176.360 154.773 1.00 360.72 ? 194 ARG L C   1 
ATOM   8598  O O   . ARG C 3 194 ? 113.160 177.436 154.843 1.00 403.30 ? 194 ARG L O   1 
ATOM   8599  C CB  . ARG C 3 194 ? 114.820 176.488 152.492 1.00 332.33 ? 194 ARG L CB  1 
ATOM   8600  C CG  . ARG C 3 194 ? 113.955 175.414 151.841 1.00 329.53 ? 194 ARG L CG  1 
ATOM   8601  C CD  . ARG C 3 194 ? 113.919 175.555 150.334 1.00 350.55 ? 194 ARG L CD  1 
ATOM   8602  N NE  . ARG C 3 194 ? 115.228 175.368 149.722 1.00 382.88 ? 194 ARG L NE  1 
ATOM   8603  C CZ  . ARG C 3 194 ? 115.521 175.641 148.454 1.00 426.20 ? 194 ARG L CZ  1 
ATOM   8604  N NH1 . ARG C 3 194 ? 116.758 175.491 148.013 1.00 461.14 ? 194 ARG L NH1 1 
ATOM   8605  N NH2 . ARG C 3 194 ? 114.582 176.067 147.625 1.00 435.40 ? 194 ARG L NH2 1 
ATOM   8606  N N   . HIS C 3 195 ? 113.296 175.225 155.339 1.00 303.31 ? 195 HIS L N   1 
ATOM   8607  C CA  . HIS C 3 195 ? 112.043 175.142 156.086 1.00 292.47 ? 195 HIS L CA  1 
ATOM   8608  C C   . HIS C 3 195 ? 112.293 174.628 157.513 1.00 265.25 ? 195 HIS L C   1 
ATOM   8609  O O   . HIS C 3 195 ? 113.204 173.834 157.741 1.00 220.99 ? 195 HIS L O   1 
ATOM   8610  C CB  . HIS C 3 195 ? 111.042 174.297 155.281 1.00 311.60 ? 195 HIS L CB  1 
ATOM   8611  C CG  . HIS C 3 195 ? 110.598 174.898 153.977 1.00 315.06 ? 195 HIS L CG  1 
ATOM   8612  N ND1 . HIS C 3 195 ? 110.262 174.176 152.848 1.00 311.37 ? 195 HIS L ND1 1 
ATOM   8613  C CD2 . HIS C 3 195 ? 110.423 176.183 153.646 1.00 325.17 ? 195 HIS L CD2 1 
ATOM   8614  C CE1 . HIS C 3 195 ? 109.905 175.005 151.877 1.00 268.34 ? 195 HIS L CE1 1 
ATOM   8615  N NE2 . HIS C 3 195 ? 109.995 176.230 152.341 1.00 304.29 ? 195 HIS L NE2 1 
ATOM   8616  N N   . ASN C 3 196 ? 111.465 175.081 158.473 1.00 256.78 ? 196 ASN L N   1 
ATOM   8617  C CA  . ASN C 3 196 ? 111.750 174.996 159.905 1.00 289.25 ? 196 ASN L CA  1 
ATOM   8618  C C   . ASN C 3 196 ? 110.917 173.935 160.647 1.00 280.07 ? 196 ASN L C   1 
ATOM   8619  O O   . ASN C 3 196 ? 111.473 173.212 161.488 1.00 228.84 ? 196 ASN L O   1 
ATOM   8620  C CB  . ASN C 3 196 ? 111.548 176.371 160.546 1.00 327.58 ? 196 ASN L CB  1 
ATOM   8621  C CG  . ASN C 3 196 ? 111.772 176.389 162.046 1.00 317.90 ? 196 ASN L CG  1 
ATOM   8622  O OD1 . ASN C 3 196 ? 110.807 176.315 162.803 1.00 283.90 ? 196 ASN L OD1 1 
ATOM   8623  N ND2 . ASN C 3 196 ? 113.021 176.481 162.488 1.00 282.08 ? 196 ASN L ND2 1 
ATOM   8624  N N   . SER C 3 197 ? 109.599 173.859 160.355 1.00 304.38 ? 197 SER L N   1 
ATOM   8625  C CA  . SER C 3 197 ? 108.631 173.064 161.112 1.00 324.90 ? 197 SER L CA  1 
ATOM   8626  C C   . SER C 3 197 ? 107.994 171.973 160.243 1.00 340.49 ? 197 SER L C   1 
ATOM   8627  O O   . SER C 3 197 ? 107.343 172.278 159.241 1.00 323.38 ? 197 SER L O   1 
ATOM   8628  C CB  . SER C 3 197 ? 107.566 173.948 161.701 1.00 322.33 ? 197 SER L CB  1 
ATOM   8629  O OG  . SER C 3 197 ? 106.733 173.215 162.591 1.00 298.50 ? 197 SER L OG  1 
ATOM   8630  N N   . TYR C 3 198 ? 108.174 170.702 160.649 1.00 308.84 ? 198 TYR L N   1 
ATOM   8631  C CA  . TYR C 3 198 ? 107.723 169.537 159.898 1.00 263.36 ? 198 TYR L CA  1 
ATOM   8632  C C   . TYR C 3 198 ? 106.631 168.812 160.679 1.00 242.43 ? 198 TYR L C   1 
ATOM   8633  O O   . TYR C 3 198 ? 106.802 168.567 161.873 1.00 186.60 ? 198 TYR L O   1 
ATOM   8634  C CB  . TYR C 3 198 ? 108.927 168.634 159.628 1.00 233.59 ? 198 TYR L CB  1 
ATOM   8635  C CG  . TYR C 3 198 ? 109.948 169.318 158.739 1.00 252.27 ? 198 TYR L CG  1 
ATOM   8636  C CD1 . TYR C 3 198 ? 109.878 169.239 157.345 1.00 230.18 ? 198 TYR L CD1 1 
ATOM   8637  C CD2 . TYR C 3 198 ? 110.973 170.067 159.309 1.00 277.44 ? 198 TYR L CD2 1 
ATOM   8638  C CE1 . TYR C 3 198 ? 110.822 169.872 156.547 1.00 262.31 ? 198 TYR L CE1 1 
ATOM   8639  C CE2 . TYR C 3 198 ? 111.912 170.714 158.521 1.00 312.14 ? 198 TYR L CE2 1 
ATOM   8640  C CZ  . TYR C 3 198 ? 111.834 170.619 157.137 1.00 307.10 ? 198 TYR L CZ  1 
ATOM   8641  O OH  . TYR C 3 198 ? 112.760 171.258 156.364 1.00 315.56 ? 198 TYR L OH  1 
ATOM   8642  N N   . THR C 3 199 ? 105.526 168.476 159.987 1.00 246.49 ? 199 THR L N   1 
ATOM   8643  C CA  . THR C 3 199 ? 104.334 167.892 160.588 1.00 252.12 ? 199 THR L CA  1 
ATOM   8644  C C   . THR C 3 199 ? 103.894 166.653 159.801 1.00 259.94 ? 199 THR L C   1 
ATOM   8645  O O   . THR C 3 199 ? 103.828 166.675 158.574 1.00 200.02 ? 199 THR L O   1 
ATOM   8646  C CB  . THR C 3 199 ? 103.199 168.920 160.642 1.00 282.28 ? 199 THR L CB  1 
ATOM   8647  O OG1 . THR C 3 199 ? 103.602 170.018 161.463 1.00 316.71 ? 199 THR L OG1 1 
ATOM   8648  C CG2 . THR C 3 199 ? 101.899 168.356 161.178 1.00 314.38 ? 199 THR L CG2 1 
ATOM   8649  N N   . CYS C 3 200 ? 103.593 165.571 160.532 1.00 267.62 ? 200 CYS L N   1 
ATOM   8650  C CA  . CYS C 3 200 ? 102.904 164.393 160.025 1.00 260.14 ? 200 CYS L CA  1 
ATOM   8651  C C   . CYS C 3 200 ? 101.551 164.316 160.735 1.00 238.73 ? 200 CYS L C   1 
ATOM   8652  O O   . CYS C 3 200 ? 101.514 164.320 161.961 1.00 210.72 ? 200 CYS L O   1 
ATOM   8653  C CB  . CYS C 3 200 ? 103.761 163.151 160.273 1.00 254.45 ? 200 CYS L CB  1 
ATOM   8654  S SG  . CYS C 3 200 ? 102.980 161.572 159.871 1.00 282.55 ? 200 CYS L SG  1 
ATOM   8655  N N   . GLU C 3 201 ? 100.447 164.253 159.975 1.00 221.50 ? 201 GLU L N   1 
ATOM   8656  C CA  . GLU C 3 201 ? 99.125  164.119 160.580 1.00 239.23 ? 201 GLU L CA  1 
ATOM   8657  C C   . GLU C 3 201 ? 98.338  163.017 159.854 1.00 255.80 ? 201 GLU L C   1 
ATOM   8658  O O   . GLU C 3 201 ? 98.313  162.941 158.625 1.00 208.35 ? 201 GLU L O   1 
ATOM   8659  C CB  . GLU C 3 201 ? 98.419  165.484 160.664 1.00 296.11 ? 201 GLU L CB  1 
ATOM   8660  C CG  . GLU C 3 201 ? 98.085  166.163 159.332 1.00 366.54 ? 201 GLU L CG  1 
ATOM   8661  C CD  . GLU C 3 201 ? 97.625  167.616 159.423 1.00 374.27 ? 201 GLU L CD  1 
ATOM   8662  O OE1 . GLU C 3 201 ? 97.604  168.181 160.534 1.00 387.70 ? 201 GLU L OE1 1 
ATOM   8663  O OE2 . GLU C 3 201 ? 97.285  168.201 158.370 1.00 332.89 ? 201 GLU L OE2 1 
ATOM   8664  N N   . ALA C 3 202 ? 97.691  162.154 160.655 1.00 273.55 ? 202 ALA L N   1 
ATOM   8665  C CA  . ALA C 3 202 ? 97.119  160.900 160.195 1.00 247.06 ? 202 ALA L CA  1 
ATOM   8666  C C   . ALA C 3 202 ? 95.620  160.879 160.482 1.00 261.68 ? 202 ALA L C   1 
ATOM   8667  O O   . ALA C 3 202 ? 95.216  161.131 161.622 1.00 222.34 ? 202 ALA L O   1 
ATOM   8668  C CB  . ALA C 3 202 ? 97.805  159.770 160.903 1.00 238.75 ? 202 ALA L CB  1 
ATOM   8669  N N   . THR C 3 203 ? 94.815  160.583 159.444 1.00 268.39 ? 203 THR L N   1 
ATOM   8670  C CA  . THR C 3 203 ? 93.373  160.443 159.589 1.00 291.02 ? 203 THR L CA  1 
ATOM   8671  C C   . THR C 3 203 ? 93.010  158.962 159.508 1.00 252.76 ? 203 THR L C   1 
ATOM   8672  O O   . THR C 3 203 ? 93.315  158.303 158.515 1.00 175.81 ? 203 THR L O   1 
ATOM   8673  C CB  . THR C 3 203 ? 92.592  161.240 158.536 1.00 339.25 ? 203 THR L CB  1 
ATOM   8674  O OG1 . THR C 3 203 ? 93.094  162.577 158.462 1.00 302.83 ? 203 THR L OG1 1 
ATOM   8675  C CG2 . THR C 3 203 ? 91.108  161.289 158.836 1.00 367.60 ? 203 THR L CG2 1 
ATOM   8676  N N   . HIS C 3 204 ? 92.349  158.472 160.564 1.00 244.37 ? 204 HIS L N   1 
ATOM   8677  C CA  . HIS C 3 204 ? 91.932  157.088 160.683 1.00 251.85 ? 204 HIS L CA  1 
ATOM   8678  C C   . HIS C 3 204 ? 90.497  157.049 161.200 1.00 264.94 ? 204 HIS L C   1 
ATOM   8679  O O   . HIS C 3 204 ? 90.127  157.879 162.026 1.00 284.26 ? 204 HIS L O   1 
ATOM   8680  C CB  . HIS C 3 204 ? 92.856  156.333 161.641 1.00 264.09 ? 204 HIS L CB  1 
ATOM   8681  C CG  . HIS C 3 204 ? 92.521  154.883 161.642 1.00 301.54 ? 204 HIS L CG  1 
ATOM   8682  N ND1 . HIS C 3 204 ? 91.628  154.328 162.525 1.00 306.80 ? 204 HIS L ND1 1 
ATOM   8683  C CD2 . HIS C 3 204 ? 92.922  153.883 160.856 1.00 276.15 ? 204 HIS L CD2 1 
ATOM   8684  C CE1 . HIS C 3 204 ? 91.527  153.034 162.266 1.00 254.29 ? 204 HIS L CE1 1 
ATOM   8685  N NE2 . HIS C 3 204 ? 92.313  152.737 161.259 1.00 206.55 ? 204 HIS L NE2 1 
ATOM   8686  N N   . LYS C 3 205 ? 89.697  156.069 160.745 1.00 282.72 ? 205 LYS L N   1 
ATOM   8687  C CA  . LYS C 3 205 ? 88.247  156.067 160.951 1.00 261.58 ? 205 LYS L CA  1 
ATOM   8688  C C   . LYS C 3 205 ? 87.805  156.031 162.427 1.00 231.25 ? 205 LYS L C   1 
ATOM   8689  O O   . LYS C 3 205 ? 86.621  156.221 162.686 1.00 265.87 ? 205 LYS L O   1 
ATOM   8690  C CB  . LYS C 3 205 ? 87.600  154.886 160.213 1.00 275.80 ? 205 LYS L CB  1 
ATOM   8691  C CG  . LYS C 3 205 ? 87.983  153.489 160.703 1.00 304.99 ? 205 LYS L CG  1 
ATOM   8692  C CD  . LYS C 3 205 ? 86.951  152.418 160.425 1.00 282.81 ? 205 LYS L CD  1 
ATOM   8693  C CE  . LYS C 3 205 ? 85.632  152.657 161.127 1.00 247.79 ? 205 LYS L CE  1 
ATOM   8694  N NZ  . LYS C 3 205 ? 84.901  151.386 161.326 1.00 284.69 ? 205 LYS L NZ  1 
ATOM   8695  N N   . THR C 3 206 ? 88.723  155.797 163.380 1.00 219.13 ? 206 THR L N   1 
ATOM   8696  C CA  . THR C 3 206 ? 88.440  155.833 164.811 1.00 246.84 ? 206 THR L CA  1 
ATOM   8697  C C   . THR C 3 206 ? 88.355  157.247 165.409 1.00 269.46 ? 206 THR L C   1 
ATOM   8698  O O   . THR C 3 206 ? 87.954  157.371 166.569 1.00 221.26 ? 206 THR L O   1 
ATOM   8699  C CB  . THR C 3 206 ? 89.503  155.036 165.585 1.00 281.33 ? 206 THR L CB  1 
ATOM   8700  O OG1 . THR C 3 206 ? 90.804  155.479 165.186 1.00 295.93 ? 206 THR L OG1 1 
ATOM   8701  C CG2 . THR C 3 206 ? 89.392  153.542 165.372 1.00 295.01 ? 206 THR L CG2 1 
ATOM   8702  N N   . SER C 3 207 ? 88.724  158.307 164.661 1.00 297.38 ? 207 SER L N   1 
ATOM   8703  C CA  . SER C 3 207 ? 88.657  159.680 165.156 1.00 318.61 ? 207 SER L CA  1 
ATOM   8704  C C   . SER C 3 207 ? 88.192  160.640 164.058 1.00 326.60 ? 207 SER L C   1 
ATOM   8705  O O   . SER C 3 207 ? 88.581  160.502 162.900 1.00 362.79 ? 207 SER L O   1 
ATOM   8706  C CB  . SER C 3 207 ? 90.000  160.099 165.712 1.00 359.09 ? 207 SER L CB  1 
ATOM   8707  O OG  . SER C 3 207 ? 89.978  161.435 166.190 1.00 353.86 ? 207 SER L OG  1 
ATOM   8708  N N   . THR C 3 208 ? 87.363  161.625 164.434 1.00 342.15 ? 208 THR L N   1 
ATOM   8709  C CA  . THR C 3 208 ? 86.917  162.673 163.525 1.00 409.80 ? 208 THR L CA  1 
ATOM   8710  C C   . THR C 3 208 ? 88.088  163.593 163.170 1.00 419.17 ? 208 THR L C   1 
ATOM   8711  O O   . THR C 3 208 ? 88.320  163.854 161.986 1.00 360.69 ? 208 THR L O   1 
ATOM   8712  C CB  . THR C 3 208 ? 85.754  163.472 164.130 1.00 489.00 ? 208 THR L CB  1 
ATOM   8713  O OG1 . THR C 3 208 ? 84.736  162.558 164.543 1.00 489.50 ? 208 THR L OG1 1 
ATOM   8714  C CG2 . THR C 3 208 ? 85.152  164.478 163.172 1.00 533.09 ? 208 THR L CG2 1 
ATOM   8715  N N   . SER C 3 209 ? 88.799  164.071 164.210 1.00 424.77 ? 209 SER L N   1 
ATOM   8716  C CA  . SER C 3 209 ? 89.995  164.892 164.071 1.00 392.28 ? 209 SER L CA  1 
ATOM   8717  C C   . SER C 3 209 ? 91.217  164.030 163.736 1.00 353.00 ? 209 SER L C   1 
ATOM   8718  O O   . SER C 3 209 ? 91.324  162.904 164.233 1.00 401.08 ? 209 SER L O   1 
ATOM   8719  C CB  . SER C 3 209 ? 90.246  165.704 165.322 1.00 375.12 ? 209 SER L CB  1 
ATOM   8720  O OG  . SER C 3 209 ? 90.296  164.875 166.473 1.00 307.20 ? 209 SER L OG  1 
ATOM   8721  N N   . PRO C 3 210 ? 92.171  164.511 162.891 1.00 316.77 ? 210 PRO L N   1 
ATOM   8722  C CA  . PRO C 3 210 ? 93.453  163.828 162.710 1.00 323.34 ? 210 PRO L CA  1 
ATOM   8723  C C   . PRO C 3 210 ? 94.301  163.797 163.983 1.00 303.42 ? 210 PRO L C   1 
ATOM   8724  O O   . PRO C 3 210 ? 94.195  164.685 164.830 1.00 209.75 ? 210 PRO L O   1 
ATOM   8725  C CB  . PRO C 3 210 ? 94.186  164.654 161.635 1.00 353.99 ? 210 PRO L CB  1 
ATOM   8726  C CG  . PRO C 3 210 ? 93.113  165.474 160.970 1.00 332.56 ? 210 PRO L CG  1 
ATOM   8727  C CD  . PRO C 3 210 ? 92.083  165.717 162.050 1.00 332.19 ? 210 PRO L CD  1 
ATOM   8728  N N   . ILE C 3 211 ? 95.139  162.758 164.092 1.00 312.86 ? 211 ILE L N   1 
ATOM   8729  C CA  . ILE C 3 211 ? 96.206  162.697 165.083 1.00 301.38 ? 211 ILE L CA  1 
ATOM   8730  C C   . ILE C 3 211 ? 97.410  163.422 164.483 1.00 290.15 ? 211 ILE L C   1 
ATOM   8731  O O   . ILE C 3 211 ? 97.628  163.331 163.277 1.00 261.34 ? 211 ILE L O   1 
ATOM   8732  C CB  . ILE C 3 211 ? 96.493  161.229 165.478 1.00 301.97 ? 211 ILE L CB  1 
ATOM   8733  C CG1 . ILE C 3 211 ? 95.268  160.589 166.146 1.00 339.19 ? 211 ILE L CG1 1 
ATOM   8734  C CG2 . ILE C 3 211 ? 97.731  161.112 166.358 1.00 300.11 ? 211 ILE L CG2 1 
ATOM   8735  C CD1 . ILE C 3 211 ? 95.209  159.076 166.083 1.00 354.00 ? 211 ILE L CD1 1 
ATOM   8736  N N   . VAL C 3 212 ? 98.174  164.133 165.331 1.00 295.65 ? 212 VAL L N   1 
ATOM   8737  C CA  . VAL C 3 212 ? 99.241  165.029 164.891 1.00 297.47 ? 212 VAL L CA  1 
ATOM   8738  C C   . VAL C 3 212 ? 100.514 164.747 165.685 1.00 282.94 ? 212 VAL L C   1 
ATOM   8739  O O   . VAL C 3 212 ? 100.466 164.553 166.899 1.00 275.47 ? 212 VAL L O   1 
ATOM   8740  C CB  . VAL C 3 212 ? 98.846  166.513 165.037 1.00 325.79 ? 212 VAL L CB  1 
ATOM   8741  C CG1 . VAL C 3 212 ? 100.004 167.457 164.722 1.00 310.78 ? 212 VAL L CG1 1 
ATOM   8742  C CG2 . VAL C 3 212 ? 97.630  166.854 164.188 1.00 359.51 ? 212 VAL L CG2 1 
ATOM   8743  N N   . LYS C 3 213 ? 101.649 164.740 164.969 1.00 270.53 ? 213 LYS L N   1 
ATOM   8744  C CA  . LYS C 3 213 ? 102.971 164.902 165.558 1.00 295.33 ? 213 LYS L CA  1 
ATOM   8745  C C   . LYS C 3 213 ? 103.816 165.809 164.658 1.00 307.74 ? 213 LYS L C   1 
ATOM   8746  O O   . LYS C 3 213 ? 103.605 165.851 163.441 1.00 246.87 ? 213 LYS L O   1 
ATOM   8747  C CB  . LYS C 3 213 ? 103.660 163.543 165.744 1.00 284.35 ? 213 LYS L CB  1 
ATOM   8748  C CG  . LYS C 3 213 ? 103.066 162.590 166.776 1.00 271.61 ? 213 LYS L CG  1 
ATOM   8749  C CD  . LYS C 3 213 ? 103.274 163.051 168.213 1.00 272.18 ? 213 LYS L CD  1 
ATOM   8750  C CE  . LYS C 3 213 ? 102.807 162.045 169.242 1.00 280.98 ? 213 LYS L CE  1 
ATOM   8751  N NZ  . LYS C 3 213 ? 102.776 162.640 170.599 1.00 254.03 ? 213 LYS L NZ  1 
ATOM   8752  N N   . SER C 3 214 ? 104.777 166.522 165.270 1.00 307.86 ? 214 SER L N   1 
ATOM   8753  C CA  . SER C 3 214 ? 105.588 167.505 164.564 1.00 282.27 ? 214 SER L CA  1 
ATOM   8754  C C   . SER C 3 214 ? 106.905 167.767 165.301 1.00 270.73 ? 214 SER L C   1 
ATOM   8755  O O   . SER C 3 214 ? 107.037 167.420 166.482 1.00 199.13 ? 214 SER L O   1 
ATOM   8756  C CB  . SER C 3 214 ? 104.804 168.787 164.360 1.00 290.92 ? 214 SER L CB  1 
ATOM   8757  O OG  . SER C 3 214 ? 104.414 169.353 165.606 1.00 300.98 ? 214 SER L OG  1 
ATOM   8758  N N   . PHE C 3 215 ? 107.865 168.383 164.582 1.00 275.07 ? 215 PHE L N   1 
ATOM   8759  C CA  . PHE C 3 215 ? 109.106 168.867 165.175 1.00 282.94 ? 215 PHE L CA  1 
ATOM   8760  C C   . PHE C 3 215 ? 109.612 170.121 164.448 1.00 303.15 ? 215 PHE L C   1 
ATOM   8761  O O   . PHE C 3 215 ? 109.295 170.338 163.274 1.00 216.66 ? 215 PHE L O   1 
ATOM   8762  C CB  . PHE C 3 215 ? 110.162 167.757 165.182 1.00 256.19 ? 215 PHE L CB  1 
ATOM   8763  C CG  . PHE C 3 215 ? 110.733 167.411 163.828 1.00 247.08 ? 215 PHE L CG  1 
ATOM   8764  C CD1 . PHE C 3 215 ? 110.105 166.483 163.012 1.00 252.42 ? 215 PHE L CD1 1 
ATOM   8765  C CD2 . PHE C 3 215 ? 111.898 168.016 163.363 1.00 291.71 ? 215 PHE L CD2 1 
ATOM   8766  C CE1 . PHE C 3 215 ? 110.633 166.162 161.766 1.00 251.86 ? 215 PHE L CE1 1 
ATOM   8767  C CE2 . PHE C 3 215 ? 112.418 167.696 162.114 1.00 272.70 ? 215 PHE L CE2 1 
ATOM   8768  C CZ  . PHE C 3 215 ? 111.788 166.768 161.318 1.00 249.19 ? 215 PHE L CZ  1 
ATOM   8769  N N   . ASN C 3 216 ? 110.402 170.929 165.179 1.00 345.79 ? 216 ASN L N   1 
ATOM   8770  C CA  . ASN C 3 216 ? 111.061 172.117 164.657 1.00 341.57 ? 216 ASN L CA  1 
ATOM   8771  C C   . ASN C 3 216 ? 112.572 171.908 164.735 1.00 321.32 ? 216 ASN L C   1 
ATOM   8772  O O   . ASN C 3 216 ? 113.077 171.617 165.830 1.00 182.52 ? 216 ASN L O   1 
ATOM   8773  C CB  . ASN C 3 216 ? 110.660 173.380 165.429 1.00 318.32 ? 216 ASN L CB  1 
ATOM   8774  C CG  . ASN C 3 216 ? 109.163 173.535 165.613 1.00 311.00 ? 216 ASN L CG  1 
ATOM   8775  O OD1 . ASN C 3 216 ? 108.391 173.239 164.703 1.00 298.84 ? 216 ASN L OD1 1 
ATOM   8776  N ND2 . ASN C 3 216 ? 108.747 173.989 166.787 1.00 306.16 ? 216 ASN L ND2 1 
ATOM   8777  N N   . ARG C 3 217 ? 113.278 172.084 163.598 1.00 326.22 ? 217 ARG L N   1 
ATOM   8778  C CA  . ARG C 3 217 ? 114.710 171.799 163.512 1.00 303.96 ? 217 ARG L CA  1 
ATOM   8779  C C   . ARG C 3 217 ? 115.480 172.887 164.291 1.00 246.13 ? 217 ARG L C   1 
ATOM   8780  O O   . ARG C 3 217 ? 116.700 173.043 164.031 1.00 223.75 ? 217 ARG L O   1 
ATOM   8781  C CB  . ARG C 3 217 ? 115.141 171.610 162.042 1.00 293.00 ? 217 ARG L CB  1 
ATOM   8782  C CG  . ARG C 3 217 ? 115.003 172.850 161.162 1.00 272.95 ? 217 ARG L CG  1 
ATOM   8783  C CD  . ARG C 3 217 ? 115.795 172.732 159.880 1.00 274.99 ? 217 ARG L CD  1 
ATOM   8784  N NE  . ARG C 3 217 ? 117.228 172.827 160.146 1.00 301.35 ? 217 ARG L NE  1 
ATOM   8785  C CZ  . ARG C 3 217 ? 118.207 172.418 159.332 1.00 337.77 ? 217 ARG L CZ  1 
ATOM   8786  N NH1 . ARG C 3 217 ? 117.960 171.883 158.143 1.00 377.05 ? 217 ARG L NH1 1 
ATOM   8787  N NH2 . ARG C 3 217 ? 119.466 172.550 159.723 1.00 338.49 ? 217 ARG L NH2 1 
ATOM   8788  N N   . GLU D 4 1   ? 114.606 115.322 162.722 1.00 283.56 ? 1   GLU H N   1 
ATOM   8789  C CA  . GLU D 4 1   ? 114.752 116.489 161.812 1.00 261.20 ? 1   GLU H CA  1 
ATOM   8790  C C   . GLU D 4 1   ? 114.821 116.025 160.361 1.00 255.64 ? 1   GLU H C   1 
ATOM   8791  O O   . GLU D 4 1   ? 115.491 115.048 160.072 1.00 284.06 ? 1   GLU H O   1 
ATOM   8792  C CB  . GLU D 4 1   ? 116.029 117.256 162.145 1.00 275.25 ? 1   GLU H CB  1 
ATOM   8793  C CG  . GLU D 4 1   ? 116.372 118.346 161.141 1.00 306.87 ? 1   GLU H CG  1 
ATOM   8794  C CD  . GLU D 4 1   ? 117.586 119.198 161.476 1.00 378.57 ? 1   GLU H CD  1 
ATOM   8795  O OE1 . GLU D 4 1   ? 118.629 118.614 161.831 1.00 428.11 ? 1   GLU H OE1 1 
ATOM   8796  O OE2 . GLU D 4 1   ? 117.492 120.446 161.364 1.00 413.36 ? 1   GLU H OE2 1 
ATOM   8797  N N   . VAL D 4 2   ? 114.117 116.742 159.468 1.00 207.23 ? 2   VAL H N   1 
ATOM   8798  C CA  . VAL D 4 2   ? 114.408 116.818 158.034 1.00 142.27 ? 2   VAL H CA  1 
ATOM   8799  C C   . VAL D 4 2   ? 114.552 118.286 157.712 1.00 118.05 ? 2   VAL H C   1 
ATOM   8800  O O   . VAL D 4 2   ? 113.685 119.077 158.127 1.00 171.91 ? 2   VAL H O   1 
ATOM   8801  C CB  . VAL D 4 2   ? 113.306 116.164 157.165 1.00 151.38 ? 2   VAL H CB  1 
ATOM   8802  C CG1 . VAL D 4 2   ? 113.403 116.543 155.692 1.00 110.53 ? 2   VAL H CG1 1 
ATOM   8803  C CG2 . VAL D 4 2   ? 113.375 114.651 157.330 1.00 238.56 ? 2   VAL H CG2 1 
ATOM   8804  N N   . GLN D 4 3   ? 115.617 118.653 156.991 1.00 94.65  ? 3   GLN H N   1 
ATOM   8805  C CA  . GLN D 4 3   ? 115.846 120.079 156.730 1.00 164.22 ? 3   GLN H CA  1 
ATOM   8806  C C   . GLN D 4 3   ? 116.568 120.294 155.402 1.00 128.96 ? 3   GLN H C   1 
ATOM   8807  O O   . GLN D 4 3   ? 117.694 119.823 155.228 1.00 124.72 ? 3   GLN H O   1 
ATOM   8808  C CB  . GLN D 4 3   ? 116.672 120.757 157.823 1.00 186.64 ? 3   GLN H CB  1 
ATOM   8809  C CG  . GLN D 4 3   ? 116.785 122.276 157.696 1.00 221.42 ? 3   GLN H CG  1 
ATOM   8810  C CD  . GLN D 4 3   ? 118.033 122.819 158.355 1.00 272.56 ? 3   GLN H CD  1 
ATOM   8811  O OE1 . GLN D 4 3   ? 118.896 123.422 157.708 1.00 337.79 ? 3   GLN H OE1 1 
ATOM   8812  N NE2 . GLN D 4 3   ? 118.131 122.599 159.657 1.00 293.94 ? 3   GLN H NE2 1 
ATOM   8813  N N   . LEU D 4 4   ? 115.880 121.024 154.512 1.00 87.13  ? 4   LEU H N   1 
ATOM   8814  C CA  . LEU D 4 4   ? 116.411 121.486 153.260 1.00 71.08  ? 4   LEU H CA  1 
ATOM   8815  C C   . LEU D 4 4   ? 116.811 122.918 153.531 1.00 111.57 ? 4   LEU H C   1 
ATOM   8816  O O   . LEU D 4 4   ? 116.059 123.649 154.215 1.00 191.47 ? 4   LEU H O   1 
ATOM   8817  C CB  . LEU D 4 4   ? 115.316 121.425 152.184 1.00 85.00  ? 4   LEU H CB  1 
ATOM   8818  C CG  . LEU D 4 4   ? 114.556 120.101 151.973 1.00 104.96 ? 4   LEU H CG  1 
ATOM   8819  C CD1 . LEU D 4 4   ? 113.721 120.092 150.658 1.00 101.77 ? 4   LEU H CD1 1 
ATOM   8820  C CD2 . LEU D 4 4   ? 115.514 118.894 151.986 1.00 119.43 ? 4   LEU H CD2 1 
ATOM   8821  N N   . GLN D 4 5   ? 117.979 123.345 152.995 1.00 110.76 ? 5   GLN H N   1 
ATOM   8822  C CA  . GLN D 4 5   ? 118.291 124.773 153.025 1.00 143.58 ? 5   GLN H CA  1 
ATOM   8823  C C   . GLN D 4 5   ? 118.897 125.228 151.706 1.00 109.13 ? 5   GLN H C   1 
ATOM   8824  O O   . GLN D 4 5   ? 119.471 124.433 150.958 1.00 120.84 ? 5   GLN H O   1 
ATOM   8825  C CB  . GLN D 4 5   ? 119.190 125.109 154.196 1.00 166.82 ? 5   GLN H CB  1 
ATOM   8826  C CG  . GLN D 4 5   ? 120.513 124.377 154.149 1.00 202.17 ? 5   GLN H CG  1 
ATOM   8827  C CD  . GLN D 4 5   ? 121.444 125.013 155.151 1.00 247.61 ? 5   GLN H CD  1 
ATOM   8828  O OE1 . GLN D 4 5   ? 122.347 125.779 154.804 1.00 267.85 ? 5   GLN H OE1 1 
ATOM   8829  N NE2 . GLN D 4 5   ? 121.215 124.702 156.418 1.00 287.65 ? 5   GLN H NE2 1 
ATOM   8830  N N   . GLN D 4 6   ? 118.703 126.529 151.481 1.00 108.42 ? 6   GLN H N   1 
ATOM   8831  C CA  . GLN D 4 6   ? 119.014 127.166 150.223 1.00 131.70 ? 6   GLN H CA  1 
ATOM   8832  C C   . GLN D 4 6   ? 119.664 128.523 150.480 1.00 131.74 ? 6   GLN H C   1 
ATOM   8833  O O   . GLN D 4 6   ? 119.415 129.166 151.498 1.00 147.01 ? 6   GLN H O   1 
ATOM   8834  C CB  . GLN D 4 6   ? 117.757 127.430 149.393 1.00 119.33 ? 6   GLN H CB  1 
ATOM   8835  C CG  . GLN D 4 6   ? 116.764 126.270 149.236 1.00 94.14  ? 6   GLN H CG  1 
ATOM   8836  C CD  . GLN D 4 6   ? 115.745 126.628 148.167 1.00 102.58 ? 6   GLN H CD  1 
ATOM   8837  O OE1 . GLN D 4 6   ? 115.880 126.250 146.999 1.00 186.94 ? 6   GLN H OE1 1 
ATOM   8838  N NE2 . GLN D 4 6   ? 114.725 127.385 148.513 1.00 82.76  ? 6   GLN H NE2 1 
ATOM   8839  N N   . SER D 4 7   ? 120.495 128.934 149.523 1.00 114.98 ? 7   SER H N   1 
ATOM   8840  C CA  . SER D 4 7   ? 120.936 130.308 149.451 1.00 128.14 ? 7   SER H CA  1 
ATOM   8841  C C   . SER D 4 7   ? 119.728 131.235 149.467 1.00 114.42 ? 7   SER H C   1 
ATOM   8842  O O   . SER D 4 7   ? 118.687 130.851 148.962 1.00 104.18 ? 7   SER H O   1 
ATOM   8843  C CB  . SER D 4 7   ? 121.823 130.536 148.220 1.00 180.53 ? 7   SER H CB  1 
ATOM   8844  O OG  . SER D 4 7   ? 121.154 130.251 146.994 1.00 128.80 ? 7   SER H OG  1 
ATOM   8845  N N   . GLY D 4 8   ? 119.916 132.463 149.994 1.00 142.23 ? 8   GLY H N   1 
ATOM   8846  C CA  . GLY D 4 8   ? 118.826 133.389 150.248 1.00 134.85 ? 8   GLY H CA  1 
ATOM   8847  C C   . GLY D 4 8   ? 118.387 134.201 149.023 1.00 141.41 ? 8   GLY H C   1 
ATOM   8848  O O   . GLY D 4 8   ? 117.202 134.515 148.888 1.00 114.10 ? 8   GLY H O   1 
ATOM   8849  N N   . ALA D 4 9   ? 119.326 134.543 148.127 1.00 122.61 ? 9   ALA H N   1 
ATOM   8850  C CA  . ALA D 4 9   ? 119.114 135.581 147.136 1.00 116.30 ? 9   ALA H CA  1 
ATOM   8851  C C   . ALA D 4 9   ? 120.071 135.387 145.974 1.00 127.43 ? 9   ALA H C   1 
ATOM   8852  O O   . ALA D 4 9   ? 121.226 135.018 146.192 1.00 175.19 ? 9   ALA H O   1 
ATOM   8853  C CB  . ALA D 4 9   ? 119.343 136.955 147.776 1.00 178.95 ? 9   ALA H CB  1 
ATOM   8854  N N   . GLU D 4 10  ? 119.599 135.696 144.772 1.00 131.23 ? 10  GLU H N   1 
ATOM   8855  C CA  . GLU D 4 10  ? 120.428 135.708 143.585 1.00 152.14 ? 10  GLU H CA  1 
ATOM   8856  C C   . GLU D 4 10  ? 119.996 136.867 142.703 1.00 155.31 ? 10  GLU H C   1 
ATOM   8857  O O   . GLU D 4 10  ? 118.799 137.126 142.554 1.00 154.02 ? 10  GLU H O   1 
ATOM   8858  C CB  . GLU D 4 10  ? 120.289 134.403 142.790 1.00 177.26 ? 10  GLU H CB  1 
ATOM   8859  C CG  . GLU D 4 10  ? 120.573 133.127 143.586 1.00 222.04 ? 10  GLU H CG  1 
ATOM   8860  C CD  . GLU D 4 10  ? 121.961 132.932 144.189 1.00 235.04 ? 10  GLU H CD  1 
ATOM   8861  O OE1 . GLU D 4 10  ? 122.903 133.637 143.762 1.00 277.90 ? 10  GLU H OE1 1 
ATOM   8862  O OE2 . GLU D 4 10  ? 122.100 132.067 145.095 1.00 310.36 ? 10  GLU H OE2 1 
ATOM   8863  N N   . LEU D 4 11  ? 120.983 137.543 142.111 1.00 166.78 ? 11  LEU H N   1 
ATOM   8864  C CA  . LEU D 4 11  ? 120.723 138.542 141.093 1.00 168.31 ? 11  LEU H CA  1 
ATOM   8865  C C   . LEU D 4 11  ? 121.184 138.024 139.724 1.00 172.07 ? 11  LEU H C   1 
ATOM   8866  O O   . LEU D 4 11  ? 122.274 137.437 139.599 1.00 127.76 ? 11  LEU H O   1 
ATOM   8867  C CB  . LEU D 4 11  ? 121.453 139.811 141.530 1.00 149.34 ? 11  LEU H CB  1 
ATOM   8868  C CG  . LEU D 4 11  ? 121.334 140.986 140.566 1.00 165.95 ? 11  LEU H CG  1 
ATOM   8869  C CD1 . LEU D 4 11  ? 119.888 141.384 140.287 1.00 164.97 ? 11  LEU H CD1 1 
ATOM   8870  C CD2 . LEU D 4 11  ? 122.113 142.161 141.130 1.00 208.37 ? 11  LEU H CD2 1 
ATOM   8871  N N   . VAL D 4 12  ? 120.338 138.249 138.708 1.00 124.49 ? 12  VAL H N   1 
ATOM   8872  C CA  . VAL D 4 12  ? 120.596 137.716 137.383 1.00 170.74 ? 12  VAL H CA  1 
ATOM   8873  C C   . VAL D 4 12  ? 120.420 138.812 136.349 1.00 173.62 ? 12  VAL H C   1 
ATOM   8874  O O   . VAL D 4 12  ? 119.339 139.374 136.287 1.00 147.56 ? 12  VAL H O   1 
ATOM   8875  C CB  . VAL D 4 12  ? 119.657 136.537 137.071 1.00 179.67 ? 12  VAL H CB  1 
ATOM   8876  C CG1 . VAL D 4 12  ? 119.874 136.016 135.649 1.00 254.75 ? 12  VAL H CG1 1 
ATOM   8877  C CG2 . VAL D 4 12  ? 119.808 135.420 138.097 1.00 207.76 ? 12  VAL H CG2 1 
ATOM   8878  N N   . LYS D 4 13  ? 121.461 139.096 135.532 1.00 195.48 ? 13  LYS H N   1 
ATOM   8879  C CA  . LYS D 4 13  ? 121.305 140.021 134.413 1.00 200.69 ? 13  LYS H CA  1 
ATOM   8880  C C   . LYS D 4 13  ? 120.465 139.340 133.333 1.00 125.70 ? 13  LYS H C   1 
ATOM   8881  O O   . LYS D 4 13  ? 120.779 138.218 132.975 1.00 127.96 ? 13  LYS H O   1 
ATOM   8882  C CB  . LYS D 4 13  ? 122.657 140.510 133.887 1.00 225.06 ? 13  LYS H CB  1 
ATOM   8883  C CG  . LYS D 4 13  ? 123.408 141.417 134.859 1.00 258.37 ? 13  LYS H CG  1 
ATOM   8884  C CD  . LYS D 4 13  ? 124.486 142.259 134.219 1.00 310.09 ? 13  LYS H CD  1 
ATOM   8885  C CE  . LYS D 4 13  ? 125.600 141.436 133.607 1.00 400.51 ? 13  LYS H CE  1 
ATOM   8886  N NZ  . LYS D 4 13  ? 126.671 142.291 133.040 1.00 451.59 ? 13  LYS H NZ  1 
ATOM   8887  N N   . PRO D 4 14  ? 119.389 139.968 132.796 1.00 124.50 ? 14  PRO H N   1 
ATOM   8888  C CA  . PRO D 4 14  ? 118.480 139.303 131.853 1.00 159.61 ? 14  PRO H CA  1 
ATOM   8889  C C   . PRO D 4 14  ? 119.174 138.510 130.742 1.00 184.74 ? 14  PRO H C   1 
ATOM   8890  O O   . PRO D 4 14  ? 120.173 138.949 130.180 1.00 221.39 ? 14  PRO H O   1 
ATOM   8891  C CB  . PRO D 4 14  ? 117.626 140.429 131.235 1.00 164.23 ? 14  PRO H CB  1 
ATOM   8892  C CG  . PRO D 4 14  ? 117.612 141.480 132.334 1.00 184.38 ? 14  PRO H CG  1 
ATOM   8893  C CD  . PRO D 4 14  ? 118.947 141.350 133.061 1.00 151.67 ? 14  PRO H CD  1 
ATOM   8894  N N   . GLY D 4 15  ? 118.617 137.325 130.469 1.00 191.74 ? 15  GLY H N   1 
ATOM   8895  C CA  . GLY D 4 15  ? 119.155 136.378 129.512 1.00 218.01 ? 15  GLY H CA  1 
ATOM   8896  C C   . GLY D 4 15  ? 120.166 135.393 130.103 1.00 205.04 ? 15  GLY H C   1 
ATOM   8897  O O   . GLY D 4 15  ? 120.407 134.358 129.483 1.00 251.07 ? 15  GLY H O   1 
ATOM   8898  N N   . ALA D 4 16  ? 120.774 135.693 131.265 1.00 143.90 ? 16  ALA H N   1 
ATOM   8899  C CA  . ALA D 4 16  ? 121.834 134.839 131.802 1.00 214.64 ? 16  ALA H CA  1 
ATOM   8900  C C   . ALA D 4 16  ? 121.241 133.602 132.489 1.00 184.75 ? 16  ALA H C   1 
ATOM   8901  O O   . ALA D 4 16  ? 120.087 133.594 132.826 1.00 151.48 ? 16  ALA H O   1 
ATOM   8902  C CB  . ALA D 4 16  ? 122.736 135.643 132.734 1.00 200.06 ? 16  ALA H CB  1 
ATOM   8903  N N   . SER D 4 17  ? 122.046 132.560 132.705 1.00 190.44 ? 17  SER H N   1 
ATOM   8904  C CA  . SER D 4 17  ? 121.655 131.438 133.539 1.00 212.35 ? 17  SER H CA  1 
ATOM   8905  C C   . SER D 4 17  ? 121.870 131.747 135.027 1.00 203.64 ? 17  SER H C   1 
ATOM   8906  O O   . SER D 4 17  ? 122.577 132.697 135.376 1.00 181.29 ? 17  SER H O   1 
ATOM   8907  C CB  . SER D 4 17  ? 122.400 130.182 133.124 1.00 287.83 ? 17  SER H CB  1 
ATOM   8908  O OG  . SER D 4 17  ? 123.790 130.265 133.439 1.00 268.96 ? 17  SER H OG  1 
ATOM   8909  N N   . VAL D 4 18  ? 121.251 130.921 135.894 1.00 167.02 ? 18  VAL H N   1 
ATOM   8910  C CA  . VAL D 4 18  ? 121.558 130.892 137.317 1.00 145.63 ? 18  VAL H CA  1 
ATOM   8911  C C   . VAL D 4 18  ? 121.461 129.485 137.898 1.00 113.64 ? 18  VAL H C   1 
ATOM   8912  O O   . VAL D 4 18  ? 120.685 128.679 137.404 1.00 137.12 ? 18  VAL H O   1 
ATOM   8913  C CB  . VAL D 4 18  ? 120.620 131.827 138.070 1.00 147.10 ? 18  VAL H CB  1 
ATOM   8914  C CG1 . VAL D 4 18  ? 119.177 131.354 137.941 1.00 98.35  ? 18  VAL H CG1 1 
ATOM   8915  C CG2 . VAL D 4 18  ? 121.086 131.991 139.526 1.00 150.10 ? 18  VAL H CG2 1 
ATOM   8916  N N   . ASN D 4 19  ? 122.286 129.206 138.920 1.00 117.36 ? 19  ASN H N   1 
ATOM   8917  C CA  . ASN D 4 19  ? 122.228 127.973 139.691 1.00 137.87 ? 19  ASN H CA  1 
ATOM   8918  C C   . ASN D 4 19  ? 121.675 128.308 141.069 1.00 139.80 ? 19  ASN H C   1 
ATOM   8919  O O   . ASN D 4 19  ? 122.251 129.146 141.773 1.00 175.33 ? 19  ASN H O   1 
ATOM   8920  C CB  . ASN D 4 19  ? 123.587 127.271 139.859 1.00 193.06 ? 19  ASN H CB  1 
ATOM   8921  C CG  . ASN D 4 19  ? 124.060 126.534 138.617 1.00 205.49 ? 19  ASN H CG  1 
ATOM   8922  O OD1 . ASN D 4 19  ? 124.097 127.127 137.535 1.00 185.64 ? 19  ASN H OD1 1 
ATOM   8923  N ND2 . ASN D 4 19  ? 124.414 125.259 138.757 1.00 188.22 ? 19  ASN H ND2 1 
ATOM   8924  N N   . LEU D 4 20  ? 120.567 127.644 141.434 1.00 103.21 ? 20  LEU H N   1 
ATOM   8925  C CA  . LEU D 4 20  ? 119.987 127.710 142.766 1.00 93.04  ? 20  LEU H CA  1 
ATOM   8926  C C   . LEU D 4 20  ? 120.222 126.343 143.390 1.00 106.94 ? 20  LEU H C   1 
ATOM   8927  O O   . LEU D 4 20  ? 120.089 125.331 142.702 1.00 115.79 ? 20  LEU H O   1 
ATOM   8928  C CB  . LEU D 4 20  ? 118.487 127.990 142.660 1.00 81.50  ? 20  LEU H CB  1 
ATOM   8929  C CG  . LEU D 4 20  ? 118.065 128.944 141.578 1.00 107.48 ? 20  LEU H CG  1 
ATOM   8930  C CD1 . LEU D 4 20  ? 116.558 128.970 141.408 1.00 100.80 ? 20  LEU H CD1 1 
ATOM   8931  C CD2 . LEU D 4 20  ? 118.618 130.302 141.885 1.00 162.77 ? 20  LEU H CD2 1 
ATOM   8932  N N   . SER D 4 21  ? 120.543 126.310 144.683 1.00 102.24 ? 21  SER H N   1 
ATOM   8933  C CA  . SER D 4 21  ? 121.077 125.097 145.274 1.00 112.65 ? 21  SER H CA  1 
ATOM   8934  C C   . SER D 4 21  ? 120.387 124.782 146.597 1.00 94.98  ? 21  SER H C   1 
ATOM   8935  O O   . SER D 4 21  ? 120.021 125.679 147.334 1.00 138.80 ? 21  SER H O   1 
ATOM   8936  C CB  . SER D 4 21  ? 122.571 125.246 145.426 1.00 196.92 ? 21  SER H CB  1 
ATOM   8937  O OG  . SER D 4 21  ? 122.917 126.368 146.256 1.00 211.41 ? 21  SER H OG  1 
ATOM   8938  N N   . CYS D 4 22  ? 120.236 123.492 146.883 1.00 84.69  ? 22  CYS H N   1 
ATOM   8939  C CA  . CYS D 4 22  ? 119.439 123.008 147.988 1.00 82.84  ? 22  CYS H CA  1 
ATOM   8940  C C   . CYS D 4 22  ? 120.105 121.829 148.650 1.00 89.72  ? 22  CYS H C   1 
ATOM   8941  O O   . CYS D 4 22  ? 120.207 120.769 148.055 1.00 128.84 ? 22  CYS H O   1 
ATOM   8942  C CB  . CYS D 4 22  ? 118.098 122.513 147.500 1.00 120.33 ? 22  CYS H CB  1 
ATOM   8943  S SG  . CYS D 4 22  ? 117.015 121.855 148.808 1.00 122.58 ? 22  CYS H SG  1 
ATOM   8944  N N   . LYS D 4 23  ? 120.595 122.020 149.865 1.00 109.25 ? 23  LYS H N   1 
ATOM   8945  C CA  . LYS D 4 23  ? 121.301 120.968 150.558 1.00 113.06 ? 23  LYS H CA  1 
ATOM   8946  C C   . LYS D 4 23  ? 120.326 120.336 151.542 1.00 105.82 ? 23  LYS H C   1 
ATOM   8947  O O   . LYS D 4 23  ? 119.798 121.020 152.445 1.00 122.15 ? 23  LYS H O   1 
ATOM   8948  C CB  . LYS D 4 23  ? 122.519 121.561 151.255 1.00 176.32 ? 23  LYS H CB  1 
ATOM   8949  C CG  . LYS D 4 23  ? 123.484 120.539 151.823 1.00 216.93 ? 23  LYS H CG  1 
ATOM   8950  C CD  . LYS D 4 23  ? 124.758 121.113 152.361 1.00 248.60 ? 23  LYS H CD  1 
ATOM   8951  C CE  . LYS D 4 23  ? 125.753 120.041 152.760 1.00 307.67 ? 23  LYS H CE  1 
ATOM   8952  N NZ  . LYS D 4 23  ? 125.252 119.143 153.832 1.00 274.01 ? 23  LYS H NZ  1 
ATOM   8953  N N   . ALA D 4 24  ? 120.123 119.029 151.344 1.00 79.99  ? 24  ALA H N   1 
ATOM   8954  C CA  . ALA D 4 24  ? 119.353 118.219 152.252 1.00 113.84 ? 24  ALA H CA  1 
ATOM   8955  C C   . ALA D 4 24  ? 120.174 117.783 153.477 1.00 118.32 ? 24  ALA H C   1 
ATOM   8956  O O   . ALA D 4 24  ? 121.392 117.690 153.465 1.00 164.19 ? 24  ALA H O   1 
ATOM   8957  C CB  . ALA D 4 24  ? 118.850 117.025 151.501 1.00 92.84  ? 24  ALA H CB  1 
ATOM   8958  N N   . SER D 4 25  ? 119.453 117.487 154.543 1.00 119.26 ? 25  SER H N   1 
ATOM   8959  C CA  . SER D 4 25  ? 119.984 116.822 155.700 1.00 133.01 ? 25  SER H CA  1 
ATOM   8960  C C   . SER D 4 25  ? 118.870 116.069 156.413 1.00 136.93 ? 25  SER H C   1 
ATOM   8961  O O   . SER D 4 25  ? 117.683 116.385 156.285 1.00 217.37 ? 25  SER H O   1 
ATOM   8962  C CB  . SER D 4 25  ? 120.596 117.857 156.599 1.00 213.09 ? 25  SER H CB  1 
ATOM   8963  O OG  . SER D 4 25  ? 119.641 118.837 156.999 1.00 195.14 ? 25  SER H OG  1 
ATOM   8964  N N   . GLY D 4 26  ? 119.248 115.076 157.193 1.00 127.19 ? 26  GLY H N   1 
ATOM   8965  C CA  . GLY D 4 26  ? 118.313 114.472 158.130 1.00 170.81 ? 26  GLY H CA  1 
ATOM   8966  C C   . GLY D 4 26  ? 117.616 113.230 157.570 1.00 172.13 ? 26  GLY H C   1 
ATOM   8967  O O   . GLY D 4 26  ? 116.730 112.666 158.222 1.00 191.63 ? 26  GLY H O   1 
ATOM   8968  N N   . TYR D 4 27  ? 118.015 112.805 156.362 1.00 135.32 ? 27  TYR H N   1 
ATOM   8969  C CA  . TYR D 4 27  ? 117.443 111.621 155.741 1.00 151.12 ? 27  TYR H CA  1 
ATOM   8970  C C   . TYR D 4 27  ? 118.405 111.117 154.667 1.00 172.05 ? 27  TYR H C   1 
ATOM   8971  O O   . TYR D 4 27  ? 119.328 111.858 154.218 1.00 128.78 ? 27  TYR H O   1 
ATOM   8972  C CB  . TYR D 4 27  ? 116.061 111.869 155.140 1.00 150.55 ? 27  TYR H CB  1 
ATOM   8973  C CG  . TYR D 4 27  ? 116.042 112.803 153.930 1.00 140.89 ? 27  TYR H CG  1 
ATOM   8974  C CD1 . TYR D 4 27  ? 115.924 114.177 154.057 1.00 150.72 ? 27  TYR H CD1 1 
ATOM   8975  C CD2 . TYR D 4 27  ? 116.160 112.283 152.649 1.00 145.38 ? 27  TYR H CD2 1 
ATOM   8976  C CE1 . TYR D 4 27  ? 115.917 114.985 152.939 1.00 117.24 ? 27  TYR H CE1 1 
ATOM   8977  C CE2 . TYR D 4 27  ? 116.158 113.079 151.526 1.00 116.02 ? 27  TYR H CE2 1 
ATOM   8978  C CZ  . TYR D 4 27  ? 116.037 114.427 151.688 1.00 103.70 ? 27  TYR H CZ  1 
ATOM   8979  O OH  . TYR D 4 27  ? 116.040 115.154 150.563 1.00 129.30 ? 27  TYR H OH  1 
ATOM   8980  N N   . THR D 4 28  ? 118.130 109.833 154.306 1.00 136.40 ? 28  THR H N   1 
ATOM   8981  C CA  . THR D 4 28  ? 118.882 109.099 153.302 1.00 152.77 ? 28  THR H CA  1 
ATOM   8982  C C   . THR D 4 28  ? 118.636 109.695 151.924 1.00 135.54 ? 28  THR H C   1 
ATOM   8983  O O   . THR D 4 28  ? 117.604 109.431 151.356 1.00 124.00 ? 28  THR H O   1 
ATOM   8984  C CB  . THR D 4 28  ? 118.472 107.623 153.244 1.00 179.26 ? 28  THR H CB  1 
ATOM   8985  O OG1 . THR D 4 28  ? 118.443 107.033 154.557 1.00 191.52 ? 28  THR H OG1 1 
ATOM   8986  C CG2 . THR D 4 28  ? 119.376 106.873 152.270 1.00 229.59 ? 28  THR H CG2 1 
ATOM   8987  N N   . PHE D 4 29  ? 119.553 110.475 151.349 1.00 148.68 ? 29  PHE H N   1 
ATOM   8988  C CA  . PHE D 4 29  ? 119.202 111.404 150.273 1.00 107.48 ? 29  PHE H CA  1 
ATOM   8989  C C   . PHE D 4 29  ? 118.679 110.745 149.012 1.00 98.66  ? 29  PHE H C   1 
ATOM   8990  O O   . PHE D 4 29  ? 117.824 111.315 148.376 1.00 118.90 ? 29  PHE H O   1 
ATOM   8991  C CB  . PHE D 4 29  ? 120.439 112.126 149.827 1.00 109.58 ? 29  PHE H CB  1 
ATOM   8992  C CG  . PHE D 4 29  ? 120.236 113.213 148.832 1.00 74.81  ? 29  PHE H CG  1 
ATOM   8993  C CD1 . PHE D 4 29  ? 119.341 114.219 149.050 1.00 75.17  ? 29  PHE H CD1 1 
ATOM   8994  C CD2 . PHE D 4 29  ? 121.019 113.260 147.694 1.00 95.86  ? 29  PHE H CD2 1 
ATOM   8995  C CE1 . PHE D 4 29  ? 119.241 115.263 148.114 1.00 113.23 ? 29  PHE H CE1 1 
ATOM   8996  C CE2 . PHE D 4 29  ? 120.903 114.296 146.766 1.00 81.70  ? 29  PHE H CE2 1 
ATOM   8997  C CZ  . PHE D 4 29  ? 120.015 115.319 146.963 1.00 61.42  ? 29  PHE H CZ  1 
ATOM   8998  N N   . THR D 4 30  ? 119.159 109.541 148.683 1.00 102.25 ? 30  THR H N   1 
ATOM   8999  C CA  . THR D 4 30  ? 118.734 108.842 147.488 1.00 118.23 ? 30  THR H CA  1 
ATOM   9000  C C   . THR D 4 30  ? 117.328 108.224 147.588 1.00 134.92 ? 30  THR H C   1 
ATOM   9001  O O   . THR D 4 30  ? 116.790 107.826 146.552 1.00 163.04 ? 30  THR H O   1 
ATOM   9002  C CB  . THR D 4 30  ? 119.763 107.769 147.158 1.00 163.49 ? 30  THR H CB  1 
ATOM   9003  O OG1 . THR D 4 30  ? 119.805 106.820 148.244 1.00 180.48 ? 30  THR H OG1 1 
ATOM   9004  C CG2 . THR D 4 30  ? 121.109 108.408 146.860 1.00 178.74 ? 30  THR H CG2 1 
ATOM   9005  N N   . ASN D 4 31  ? 116.720 108.135 148.789 1.00 79.00  ? 31  ASN H N   1 
ATOM   9006  C CA  . ASN D 4 31  ? 115.421 107.509 148.934 1.00 91.49  ? 31  ASN H CA  1 
ATOM   9007  C C   . ASN D 4 31  ? 114.280 108.368 148.421 1.00 84.55  ? 31  ASN H C   1 
ATOM   9008  O O   . ASN D 4 31  ? 113.206 107.810 148.216 1.00 129.86 ? 31  ASN H O   1 
ATOM   9009  C CB  . ASN D 4 31  ? 115.044 107.156 150.375 1.00 118.47 ? 31  ASN H CB  1 
ATOM   9010  C CG  . ASN D 4 31  ? 115.586 105.801 150.834 1.00 178.15 ? 31  ASN H CG  1 
ATOM   9011  O OD1 . ASN D 4 31  ? 116.247 105.065 150.095 1.00 161.15 ? 31  ASN H OD1 1 
ATOM   9012  N ND2 . ASN D 4 31  ? 115.304 105.451 152.083 1.00 232.05 ? 31  ASN H ND2 1 
ATOM   9013  N N   . TYR D 4 32  ? 114.468 109.663 148.214 1.00 61.79  ? 32  TYR H N   1 
ATOM   9014  C CA  . TYR D 4 32  ? 113.325 110.536 147.982 1.00 72.29  ? 32  TYR H CA  1 
ATOM   9015  C C   . TYR D 4 32  ? 113.571 111.575 146.912 1.00 71.15  ? 32  TYR H C   1 
ATOM   9016  O O   . TYR D 4 32  ? 114.644 112.253 146.935 1.00 70.52  ? 32  TYR H O   1 
ATOM   9017  C CB  . TYR D 4 32  ? 112.981 111.329 149.245 1.00 60.68  ? 32  TYR H CB  1 
ATOM   9018  C CG  . TYR D 4 32  ? 112.607 110.447 150.401 1.00 69.13  ? 32  TYR H CG  1 
ATOM   9019  C CD1 . TYR D 4 32  ? 111.338 109.981 150.537 1.00 99.34  ? 32  TYR H CD1 1 
ATOM   9020  C CD2 . TYR D 4 32  ? 113.528 110.070 151.331 1.00 103.78 ? 32  TYR H CD2 1 
ATOM   9021  C CE1 . TYR D 4 32  ? 110.970 109.170 151.595 1.00 156.79 ? 32  TYR H CE1 1 
ATOM   9022  C CE2 . TYR D 4 32  ? 113.192 109.259 152.402 1.00 129.52 ? 32  TYR H CE2 1 
ATOM   9023  C CZ  . TYR D 4 32  ? 111.904 108.805 152.541 1.00 142.76 ? 32  TYR H CZ  1 
ATOM   9024  O OH  . TYR D 4 32  ? 111.575 108.010 153.595 1.00 191.98 ? 32  TYR H OH  1 
ATOM   9025  N N   . TRP D 4 33  ? 112.550 111.723 146.032 1.00 49.71  ? 33  TRP H N   1 
ATOM   9026  C CA  . TRP D 4 33  ? 112.860 112.642 144.979 1.00 66.55  ? 33  TRP H CA  1 
ATOM   9027  C C   . TRP D 4 33  ? 112.729 114.101 145.438 1.00 64.24  ? 33  TRP H C   1 
ATOM   9028  O O   . TRP D 4 33  ? 111.991 114.343 146.346 1.00 77.63  ? 33  TRP H O   1 
ATOM   9029  C CB  . TRP D 4 33  ? 111.971 112.467 143.802 1.00 71.74  ? 33  TRP H CB  1 
ATOM   9030  C CG  . TRP D 4 33  ? 111.996 111.220 143.032 1.00 68.68  ? 33  TRP H CG  1 
ATOM   9031  C CD1 . TRP D 4 33  ? 112.070 109.970 143.481 1.00 83.88  ? 33  TRP H CD1 1 
ATOM   9032  C CD2 . TRP D 4 33  ? 111.812 111.155 141.606 1.00 64.83  ? 33  TRP H CD2 1 
ATOM   9033  N NE1 . TRP D 4 33  ? 111.970 109.112 142.418 1.00 85.91  ? 33  TRP H NE1 1 
ATOM   9034  C CE2 . TRP D 4 33  ? 111.805 109.821 141.267 1.00 62.42  ? 33  TRP H CE2 1 
ATOM   9035  C CE3 . TRP D 4 33  ? 111.649 112.092 140.600 1.00 67.15  ? 33  TRP H CE3 1 
ATOM   9036  C CZ2 . TRP D 4 33  ? 111.641 109.402 139.972 1.00 74.03  ? 33  TRP H CZ2 1 
ATOM   9037  C CZ3 . TRP D 4 33  ? 111.532 111.673 139.322 1.00 75.79  ? 33  TRP H CZ3 1 
ATOM   9038  C CH2 . TRP D 4 33  ? 111.478 110.344 139.014 1.00 61.18  ? 33  TRP H CH2 1 
ATOM   9039  N N   . MET D 4 34  ? 113.427 115.006 144.758 1.00 59.71  ? 34  MET H N   1 
ATOM   9040  C CA  . MET D 4 34  ? 113.486 116.400 145.083 1.00 57.86  ? 34  MET H CA  1 
ATOM   9041  C C   . MET D 4 34  ? 112.748 117.243 144.055 1.00 58.82  ? 34  MET H C   1 
ATOM   9042  O O   . MET D 4 34  ? 112.974 117.132 142.861 1.00 53.56  ? 34  MET H O   1 
ATOM   9043  C CB  . MET D 4 34  ? 114.949 116.825 145.099 1.00 52.82  ? 34  MET H CB  1 
ATOM   9044  C CG  . MET D 4 34  ? 115.091 118.175 145.762 1.00 59.82  ? 34  MET H CG  1 
ATOM   9045  S SD  . MET D 4 34  ? 114.694 117.819 147.535 1.00 111.42 ? 34  MET H SD  1 
ATOM   9046  C CE  . MET D 4 34  ? 116.105 116.801 147.930 1.00 121.87 ? 34  MET H CE  1 
ATOM   9047  N N   . HIS D 4 35  ? 111.850 118.096 144.520 1.00 57.19  ? 35  HIS H N   1 
ATOM   9048  C CA  . HIS D 4 35  ? 111.041 118.891 143.627 1.00 59.91  ? 35  HIS H CA  1 
ATOM   9049  C C   . HIS D 4 35  ? 111.430 120.376 143.770 1.00 64.27  ? 35  HIS H C   1 
ATOM   9050  O O   . HIS D 4 35  ? 111.855 120.858 144.837 1.00 62.30  ? 35  HIS H O   1 
ATOM   9051  C CB  . HIS D 4 35  ? 109.598 118.786 144.060 1.00 60.55  ? 35  HIS H CB  1 
ATOM   9052  C CG  . HIS D 4 35  ? 109.029 117.477 144.102 1.00 57.19  ? 35  HIS H CG  1 
ATOM   9053  N ND1 . HIS D 4 35  ? 108.132 117.111 143.168 1.00 47.34  ? 35  HIS H ND1 1 
ATOM   9054  C CD2 . HIS D 4 35  ? 109.186 116.418 144.946 1.00 72.92  ? 35  HIS H CD2 1 
ATOM   9055  C CE1 . HIS D 4 35  ? 107.734 115.850 143.484 1.00 69.38  ? 35  HIS H CE1 1 
ATOM   9056  N NE2 . HIS D 4 35  ? 108.363 115.390 144.553 1.00 55.61  ? 35  HIS H NE2 1 
ATOM   9057  N N   . TRP D 4 36  ? 111.256 121.129 142.679 1.00 55.86  ? 36  TRP H N   1 
ATOM   9058  C CA  . TRP D 4 36  ? 111.443 122.574 142.627 1.00 48.82  ? 36  TRP H CA  1 
ATOM   9059  C C   . TRP D 4 36  ? 110.129 123.271 142.313 1.00 58.27  ? 36  TRP H C   1 
ATOM   9060  O O   . TRP D 4 36  ? 109.480 122.957 141.325 1.00 69.20  ? 36  TRP H O   1 
ATOM   9061  C CB  . TRP D 4 36  ? 112.487 122.862 141.547 1.00 72.24  ? 36  TRP H CB  1 
ATOM   9062  C CG  . TRP D 4 36  ? 113.831 122.457 142.095 1.00 89.62  ? 36  TRP H CG  1 
ATOM   9063  C CD1 . TRP D 4 36  ? 114.420 121.255 141.982 1.00 103.29 ? 36  TRP H CD1 1 
ATOM   9064  C CD2 . TRP D 4 36  ? 114.726 123.231 142.888 1.00 67.61  ? 36  TRP H CD2 1 
ATOM   9065  N NE1 . TRP D 4 36  ? 115.606 121.229 142.633 1.00 102.14 ? 36  TRP H NE1 1 
ATOM   9066  C CE2 . TRP D 4 36  ? 115.809 122.441 143.193 1.00 76.88  ? 36  TRP H CE2 1 
ATOM   9067  C CE3 . TRP D 4 36  ? 114.708 124.523 143.331 1.00 69.20  ? 36  TRP H CE3 1 
ATOM   9068  C CZ2 . TRP D 4 36  ? 116.871 122.892 143.937 1.00 103.48 ? 36  TRP H CZ2 1 
ATOM   9069  C CZ3 . TRP D 4 36  ? 115.749 124.984 144.060 1.00 91.50  ? 36  TRP H CZ3 1 
ATOM   9070  C CH2 . TRP D 4 36  ? 116.823 124.178 144.371 1.00 96.81  ? 36  TRP H CH2 1 
ATOM   9071  N N   . VAL D 4 37  ? 109.692 124.211 143.137 1.00 59.01  ? 37  VAL H N   1 
ATOM   9072  C CA  . VAL D 4 37  ? 108.433 124.917 142.965 1.00 41.91  ? 37  VAL H CA  1 
ATOM   9073  C C   . VAL D 4 37  ? 108.773 126.378 143.083 1.00 51.84  ? 37  VAL H C   1 
ATOM   9074  O O   . VAL D 4 37  ? 109.709 126.787 143.739 1.00 64.48  ? 37  VAL H O   1 
ATOM   9075  C CB  . VAL D 4 37  ? 107.498 124.523 144.098 1.00 45.27  ? 37  VAL H CB  1 
ATOM   9076  C CG1 . VAL D 4 37  ? 106.244 125.376 144.214 1.00 69.98  ? 37  VAL H CG1 1 
ATOM   9077  C CG2 . VAL D 4 37  ? 107.093 123.083 143.978 1.00 55.05  ? 37  VAL H CG2 1 
ATOM   9078  N N   . ARG D 4 38  ? 108.021 127.224 142.417 1.00 74.66  ? 38  ARG H N   1 
ATOM   9079  C CA  . ARG D 4 38  ? 108.299 128.656 142.250 1.00 55.00  ? 38  ARG H CA  1 
ATOM   9080  C C   . ARG D 4 38  ? 107.058 129.450 142.662 1.00 62.29  ? 38  ARG H C   1 
ATOM   9081  O O   . ARG D 4 38  ? 105.918 128.963 142.612 1.00 110.66 ? 38  ARG H O   1 
ATOM   9082  C CB  . ARG D 4 38  ? 108.512 128.711 140.756 1.00 58.28  ? 38  ARG H CB  1 
ATOM   9083  C CG  . ARG D 4 38  ? 108.644 130.077 140.143 1.00 78.15  ? 38  ARG H CG  1 
ATOM   9084  C CD  . ARG D 4 38  ? 108.147 130.229 138.716 1.00 95.16  ? 38  ARG H CD  1 
ATOM   9085  N NE  . ARG D 4 38  ? 109.210 130.628 137.798 1.00 70.52  ? 38  ARG H NE  1 
ATOM   9086  C CZ  . ARG D 4 38  ? 108.957 131.007 136.573 1.00 124.70 ? 38  ARG H CZ  1 
ATOM   9087  N NH1 . ARG D 4 38  ? 109.976 131.478 135.860 1.00 185.00 ? 38  ARG H NH1 1 
ATOM   9088  N NH2 . ARG D 4 38  ? 107.709 130.931 136.085 1.00 120.99 ? 38  ARG H NH2 1 
ATOM   9089  N N   . LEU D 4 39  ? 107.246 130.674 143.085 1.00 72.48  ? 39  LEU H N   1 
ATOM   9090  C CA  . LEU D 4 39  ? 106.129 131.518 143.499 1.00 91.57  ? 39  LEU H CA  1 
ATOM   9091  C C   . LEU D 4 39  ? 106.334 132.944 142.958 1.00 108.33 ? 39  LEU H C   1 
ATOM   9092  O O   . LEU D 4 39  ? 106.984 133.809 143.598 1.00 86.01  ? 39  LEU H O   1 
ATOM   9093  C CB  . LEU D 4 39  ? 106.095 131.475 145.017 1.00 74.57  ? 39  LEU H CB  1 
ATOM   9094  C CG  . LEU D 4 39  ? 105.113 132.408 145.645 1.00 79.47  ? 39  LEU H CG  1 
ATOM   9095  C CD1 . LEU D 4 39  ? 103.721 132.054 145.174 1.00 123.63 ? 39  LEU H CD1 1 
ATOM   9096  C CD2 . LEU D 4 39  ? 105.264 132.326 147.155 1.00 107.80 ? 39  LEU H CD2 1 
ATOM   9097  N N   . ARG D 4 40  ? 105.796 133.149 141.728 1.00 109.07 ? 40  ARG H N   1 
ATOM   9098  C CA  . ARG D 4 40  ? 105.707 134.448 141.096 1.00 99.50  ? 40  ARG H CA  1 
ATOM   9099  C C   . ARG D 4 40  ? 104.922 135.316 142.071 1.00 119.91 ? 40  ARG H C   1 
ATOM   9100  O O   . ARG D 4 40  ? 103.906 134.858 142.581 1.00 172.34 ? 40  ARG H O   1 
ATOM   9101  C CB  . ARG D 4 40  ? 104.994 134.349 139.731 1.00 185.87 ? 40  ARG H CB  1 
ATOM   9102  C CG  . ARG D 4 40  ? 105.711 133.642 138.570 1.00 169.65 ? 40  ARG H CG  1 
ATOM   9103  C CD  . ARG D 4 40  ? 106.984 134.324 138.122 1.00 161.24 ? 40  ARG H CD  1 
ATOM   9104  N NE  . ARG D 4 40  ? 107.012 135.787 138.297 1.00 243.77 ? 40  ARG H NE  1 
ATOM   9105  C CZ  . ARG D 4 40  ? 106.267 136.683 137.635 1.00 311.73 ? 40  ARG H CZ  1 
ATOM   9106  N NH1 . ARG D 4 40  ? 106.369 137.976 137.900 1.00 293.07 ? 40  ARG H NH1 1 
ATOM   9107  N NH2 . ARG D 4 40  ? 105.418 136.289 136.704 1.00 338.21 ? 40  ARG H NH2 1 
ATOM   9108  N N   . PRO D 4 41  ? 105.304 136.578 142.375 1.00 153.71 ? 41  PRO H N   1 
ATOM   9109  C CA  . PRO D 4 41  ? 104.476 137.419 143.245 1.00 160.28 ? 41  PRO H CA  1 
ATOM   9110  C C   . PRO D 4 41  ? 103.038 137.628 142.741 1.00 190.70 ? 41  PRO H C   1 
ATOM   9111  O O   . PRO D 4 41  ? 102.804 137.914 141.543 1.00 118.39 ? 41  PRO H O   1 
ATOM   9112  C CB  . PRO D 4 41  ? 105.248 138.742 143.234 1.00 231.66 ? 41  PRO H CB  1 
ATOM   9113  C CG  . PRO D 4 41  ? 106.676 138.323 142.964 1.00 224.38 ? 41  PRO H CG  1 
ATOM   9114  C CD  . PRO D 4 41  ? 106.535 137.246 141.916 1.00 219.89 ? 41  PRO H CD  1 
ATOM   9115  N N   . GLY D 4 42  ? 102.091 137.460 143.693 1.00 205.91 ? 42  GLY H N   1 
ATOM   9116  C CA  . GLY D 4 42  ? 100.660 137.652 143.502 1.00 243.44 ? 42  GLY H CA  1 
ATOM   9117  C C   . GLY D 4 42  ? 99.995  136.766 142.445 1.00 198.04 ? 42  GLY H C   1 
ATOM   9118  O O   . GLY D 4 42  ? 98.948  137.135 141.920 1.00 247.94 ? 42  GLY H O   1 
ATOM   9119  N N   . GLN D 4 43  ? 100.580 135.606 142.156 1.00 187.40 ? 43  GLN H N   1 
ATOM   9120  C CA  . GLN D 4 43  ? 100.206 134.796 141.004 1.00 161.73 ? 43  GLN H CA  1 
ATOM   9121  C C   . GLN D 4 43  ? 100.225 133.280 141.316 1.00 169.25 ? 43  GLN H C   1 
ATOM   9122  O O   . GLN D 4 43  ? 100.015 132.469 140.404 1.00 167.30 ? 43  GLN H O   1 
ATOM   9123  C CB  . GLN D 4 43  ? 101.143 135.248 139.876 1.00 157.34 ? 43  GLN H CB  1 
ATOM   9124  C CG  . GLN D 4 43  ? 101.048 134.454 138.580 1.00 222.30 ? 43  GLN H CG  1 
ATOM   9125  C CD  . GLN D 4 43  ? 101.910 134.970 137.457 1.00 270.45 ? 43  GLN H CD  1 
ATOM   9126  O OE1 . GLN D 4 43  ? 102.286 136.140 137.430 1.00 269.00 ? 43  GLN H OE1 1 
ATOM   9127  N NE2 . GLN D 4 43  ? 102.219 134.086 136.514 1.00 290.80 ? 43  GLN H NE2 1 
ATOM   9128  N N   . GLY D 4 44  ? 100.451 132.856 142.578 1.00 143.23 ? 44  GLY H N   1 
ATOM   9129  C CA  . GLY D 4 44  ? 100.241 131.468 142.986 1.00 152.53 ? 44  GLY H CA  1 
ATOM   9130  C C   . GLY D 4 44  ? 101.403 130.533 142.639 1.00 140.55 ? 44  GLY H C   1 
ATOM   9131  O O   . GLY D 4 44  ? 102.149 130.782 141.696 1.00 138.34 ? 44  GLY H O   1 
ATOM   9132  N N   . LEU D 4 45  ? 101.548 129.451 143.419 1.00 105.58 ? 45  LEU H N   1 
ATOM   9133  C CA  . LEU D 4 45  ? 102.682 128.533 143.293 1.00 90.70  ? 45  LEU H CA  1 
ATOM   9134  C C   . LEU D 4 45  ? 102.629 127.773 141.959 1.00 97.91  ? 45  LEU H C   1 
ATOM   9135  O O   . LEU D 4 45  ? 101.542 127.557 141.412 1.00 123.20 ? 45  LEU H O   1 
ATOM   9136  C CB  . LEU D 4 45  ? 102.609 127.487 144.401 1.00 84.71  ? 45  LEU H CB  1 
ATOM   9137  C CG  . LEU D 4 45  ? 102.712 128.009 145.809 1.00 80.37  ? 45  LEU H CG  1 
ATOM   9138  C CD1 . LEU D 4 45  ? 102.156 126.996 146.766 1.00 71.62  ? 45  LEU H CD1 1 
ATOM   9139  C CD2 . LEU D 4 45  ? 104.176 128.207 146.043 1.00 96.71  ? 45  LEU H CD2 1 
ATOM   9140  N N   . GLU D 4 46  ? 103.793 127.367 141.442 1.00 81.03  ? 46  GLU H N   1 
ATOM   9141  C CA  . GLU D 4 46  ? 103.929 126.691 140.152 1.00 82.03  ? 46  GLU H CA  1 
ATOM   9142  C C   . GLU D 4 46  ? 105.104 125.721 140.244 1.00 71.22  ? 46  GLU H C   1 
ATOM   9143  O O   . GLU D 4 46  ? 106.186 126.077 140.762 1.00 65.92  ? 46  GLU H O   1 
ATOM   9144  C CB  . GLU D 4 46  ? 104.217 127.744 139.064 1.00 136.77 ? 46  GLU H CB  1 
ATOM   9145  C CG  . GLU D 4 46  ? 104.421 127.200 137.658 1.00 203.59 ? 46  GLU H CG  1 
ATOM   9146  C CD  . GLU D 4 46  ? 104.633 128.292 136.607 1.00 276.53 ? 46  GLU H CD  1 
ATOM   9147  O OE1 . GLU D 4 46  ? 105.268 129.364 136.914 1.00 205.25 ? 46  GLU H OE1 1 
ATOM   9148  O OE2 . GLU D 4 46  ? 104.161 128.076 135.459 1.00 371.93 ? 46  GLU H OE2 1 
ATOM   9149  N N   . TRP D 4 47  ? 104.932 124.503 139.730 1.00 67.09  ? 47  TRP H N   1 
ATOM   9150  C CA  . TRP D 4 47  ? 105.919 123.455 140.027 1.00 63.70  ? 47  TRP H CA  1 
ATOM   9151  C C   . TRP D 4 47  ? 106.750 123.232 138.806 1.00 74.47  ? 47  TRP H C   1 
ATOM   9152  O O   . TRP D 4 47  ? 106.211 123.204 137.676 1.00 88.73  ? 47  TRP H O   1 
ATOM   9153  C CB  . TRP D 4 47  ? 105.165 122.198 140.357 1.00 69.30  ? 47  TRP H CB  1 
ATOM   9154  C CG  . TRP D 4 47  ? 105.826 120.864 140.538 1.00 64.26  ? 47  TRP H CG  1 
ATOM   9155  C CD1 . TRP D 4 47  ? 106.096 120.326 141.746 1.00 69.93  ? 47  TRP H CD1 1 
ATOM   9156  C CD2 . TRP D 4 47  ? 106.183 119.829 139.587 1.00 51.04  ? 47  TRP H CD2 1 
ATOM   9157  N NE1 . TRP D 4 47  ? 106.634 119.067 141.613 1.00 47.39  ? 47  TRP H NE1 1 
ATOM   9158  C CE2 . TRP D 4 47  ? 106.681 118.749 140.308 1.00 40.28  ? 47  TRP H CE2 1 
ATOM   9159  C CE3 . TRP D 4 47  ? 106.141 119.722 138.209 1.00 53.56  ? 47  TRP H CE3 1 
ATOM   9160  C CZ2 . TRP D 4 47  ? 107.124 117.616 139.702 1.00 50.01  ? 47  TRP H CZ2 1 
ATOM   9161  C CZ3 . TRP D 4 47  ? 106.570 118.594 137.592 1.00 47.52  ? 47  TRP H CZ3 1 
ATOM   9162  C CH2 . TRP D 4 47  ? 107.034 117.561 138.333 1.00 61.07  ? 47  TRP H CH2 1 
ATOM   9163  N N   . ILE D 4 48  ? 108.060 123.126 139.037 1.00 69.81  ? 48  ILE H N   1 
ATOM   9164  C CA  . ILE D 4 48  ? 108.996 123.140 137.924 1.00 73.68  ? 48  ILE H CA  1 
ATOM   9165  C C   . ILE D 4 48  ? 109.187 121.707 137.463 1.00 60.35  ? 48  ILE H C   1 
ATOM   9166  O O   . ILE D 4 48  ? 109.038 121.332 136.313 1.00 58.57  ? 48  ILE H O   1 
ATOM   9167  C CB  . ILE D 4 48  ? 110.277 123.853 138.389 1.00 68.59  ? 48  ILE H CB  1 
ATOM   9168  C CG1 . ILE D 4 48  ? 109.964 125.308 138.740 1.00 59.54  ? 48  ILE H CG1 1 
ATOM   9169  C CG2 . ILE D 4 48  ? 111.370 123.705 137.386 1.00 64.75  ? 48  ILE H CG2 1 
ATOM   9170  C CD1 . ILE D 4 48  ? 111.182 125.990 139.132 1.00 87.70  ? 48  ILE H CD1 1 
ATOM   9171  N N   . GLY D 4 49  ? 109.554 120.869 138.392 1.00 75.40  ? 49  GLY H N   1 
ATOM   9172  C CA  . GLY D 4 49  ? 110.006 119.541 138.044 1.00 67.71  ? 49  GLY H CA  1 
ATOM   9173  C C   . GLY D 4 49  ? 110.685 118.902 139.246 1.00 70.89  ? 49  GLY H C   1 
ATOM   9174  O O   . GLY D 4 49  ? 110.883 119.512 140.310 1.00 81.09  ? 49  GLY H O   1 
ATOM   9175  N N   . GLU D 4 50  ? 111.052 117.663 139.014 1.00 62.26  ? 50  GLU H N   1 
ATOM   9176  C CA  . GLU D 4 50  ? 111.692 116.922 140.053 1.00 59.24  ? 50  GLU H CA  1 
ATOM   9177  C C   . GLU D 4 50  ? 112.767 115.998 139.493 1.00 52.82  ? 50  GLU H C   1 
ATOM   9178  O O   . GLU D 4 50  ? 112.826 115.710 138.292 1.00 47.27  ? 50  GLU H O   1 
ATOM   9179  C CB  . GLU D 4 50  ? 110.604 116.089 140.640 1.00 61.53  ? 50  GLU H CB  1 
ATOM   9180  C CG  . GLU D 4 50  ? 109.961 115.121 139.643 1.00 53.30  ? 50  GLU H CG  1 
ATOM   9181  C CD  . GLU D 4 50  ? 109.025 114.100 140.328 1.00 68.00  ? 50  GLU H CD  1 
ATOM   9182  O OE1 . GLU D 4 50  ? 108.423 114.349 141.378 1.00 42.72  ? 50  GLU H OE1 1 
ATOM   9183  O OE2 . GLU D 4 50  ? 108.864 113.023 139.786 1.00 106.28 ? 50  GLU H OE2 1 
ATOM   9184  N N   . ILE D 4 51  ? 113.598 115.550 140.430 1.00 41.43  ? 51  ILE H N   1 
ATOM   9185  C CA  . ILE D 4 51  ? 114.827 114.880 140.121 1.00 51.19  ? 51  ILE H CA  1 
ATOM   9186  C C   . ILE D 4 51  ? 114.909 113.741 141.093 1.00 58.84  ? 51  ILE H C   1 
ATOM   9187  O O   . ILE D 4 51  ? 114.513 113.894 142.215 1.00 83.22  ? 51  ILE H O   1 
ATOM   9188  C CB  . ILE D 4 51  ? 116.027 115.824 140.253 1.00 59.40  ? 51  ILE H CB  1 
ATOM   9189  C CG1 . ILE D 4 51  ? 117.398 115.194 140.333 1.00 64.34  ? 51  ILE H CG1 1 
ATOM   9190  C CG2 . ILE D 4 51  ? 115.936 116.668 141.471 1.00 83.72  ? 51  ILE H CG2 1 
ATOM   9191  C CD1 . ILE D 4 51  ? 117.818 114.768 138.950 1.00 110.29 ? 51  ILE H CD1 1 
ATOM   9192  N N   . ASP D 4 52  ? 115.457 112.638 140.629 1.00 73.50  ? 52  ASP H N   1 
ATOM   9193  C CA  . ASP D 4 52  ? 115.691 111.496 141.447 1.00 68.96  ? 52  ASP H CA  1 
ATOM   9194  C C   . ASP D 4 52  ? 117.194 111.447 141.758 1.00 80.05  ? 52  ASP H C   1 
ATOM   9195  O O   . ASP D 4 52  ? 118.028 111.171 140.877 1.00 122.05 ? 52  ASP H O   1 
ATOM   9196  C CB  . ASP D 4 52  ? 115.228 110.266 140.690 1.00 71.31  ? 52  ASP H CB  1 
ATOM   9197  C CG  . ASP D 4 52  ? 115.362 108.987 141.487 1.00 103.61 ? 52  ASP H CG  1 
ATOM   9198  O OD1 . ASP D 4 52  ? 116.166 108.961 142.494 1.00 151.73 ? 52  ASP H OD1 1 
ATOM   9199  O OD2 . ASP D 4 52  ? 114.682 108.020 141.101 1.00 137.13 ? 52  ASP H OD2 1 
ATOM   9200  N N   . PRO D 4 53  ? 117.619 111.603 143.012 1.00 63.61  ? 53  PRO H N   1 
ATOM   9201  C CA  . PRO D 4 53  ? 119.018 111.553 143.282 1.00 85.17  ? 53  PRO H CA  1 
ATOM   9202  C C   . PRO D 4 53  ? 119.708 110.220 143.017 1.00 105.00 ? 53  PRO H C   1 
ATOM   9203  O O   . PRO D 4 53  ? 120.952 110.230 142.948 1.00 155.83 ? 53  PRO H O   1 
ATOM   9204  C CB  . PRO D 4 53  ? 119.071 111.810 144.795 1.00 113.14 ? 53  PRO H CB  1 
ATOM   9205  C CG  . PRO D 4 53  ? 117.819 112.519 145.079 1.00 128.30 ? 53  PRO H CG  1 
ATOM   9206  C CD  . PRO D 4 53  ? 116.829 111.770 144.228 1.00 93.90  ? 53  PRO H CD  1 
ATOM   9207  N N   . SER D 4 54  ? 118.939 109.120 142.909 1.00 87.77  ? 54  SER H N   1 
ATOM   9208  C CA  . SER D 4 54  ? 119.534 107.811 142.759 1.00 103.88 ? 54  SER H CA  1 
ATOM   9209  C C   . SER D 4 54  ? 120.090 107.568 141.350 1.00 100.94 ? 54  SER H C   1 
ATOM   9210  O O   . SER D 4 54  ? 120.876 106.630 141.183 1.00 159.56 ? 54  SER H O   1 
ATOM   9211  C CB  . SER D 4 54  ? 118.560 106.725 143.191 1.00 145.67 ? 54  SER H CB  1 
ATOM   9212  O OG  . SER D 4 54  ? 117.385 106.690 142.402 1.00 175.52 ? 54  SER H OG  1 
ATOM   9213  N N   . ASP D 4 55  ? 119.688 108.352 140.339 1.00 96.69  ? 55  ASP H N   1 
ATOM   9214  C CA  . ASP D 4 55  ? 120.137 108.136 138.976 1.00 116.49 ? 55  ASP H CA  1 
ATOM   9215  C C   . ASP D 4 55  ? 120.055 109.388 138.112 1.00 105.65 ? 55  ASP H C   1 
ATOM   9216  O O   . ASP D 4 55  ? 120.247 109.288 136.891 1.00 129.68 ? 55  ASP H O   1 
ATOM   9217  C CB  . ASP D 4 55  ? 119.351 106.966 138.346 1.00 172.00 ? 55  ASP H CB  1 
ATOM   9218  C CG  . ASP D 4 55  ? 117.834 107.089 138.202 1.00 200.13 ? 55  ASP H CG  1 
ATOM   9219  O OD1 . ASP D 4 55  ? 117.379 108.202 137.967 1.00 157.52 ? 55  ASP H OD1 1 
ATOM   9220  O OD2 . ASP D 4 55  ? 117.118 106.054 138.298 1.00 244.06 ? 55  ASP H OD2 1 
ATOM   9221  N N   . SER D 4 56  ? 119.773 110.546 138.721 1.00 81.26  ? 56  SER H N   1 
ATOM   9222  C CA  . SER D 4 56  ? 119.726 111.821 138.018 1.00 100.58 ? 56  SER H CA  1 
ATOM   9223  C C   . SER D 4 56  ? 118.687 111.945 136.879 1.00 114.47 ? 56  SER H C   1 
ATOM   9224  O O   . SER D 4 56  ? 118.758 112.922 136.116 1.00 109.64 ? 56  SER H O   1 
ATOM   9225  C CB  . SER D 4 56  ? 121.125 112.219 137.572 1.00 147.59 ? 56  SER H CB  1 
ATOM   9226  O OG  . SER D 4 56  ? 122.059 112.095 138.658 1.00 194.40 ? 56  SER H OG  1 
ATOM   9227  N N   . TYR D 4 57  ? 117.710 111.014 136.778 1.00 101.02 ? 57  TYR H N   1 
ATOM   9228  C CA  . TYR D 4 57  ? 116.511 111.202 135.971 1.00 98.40  ? 57  TYR H CA  1 
ATOM   9229  C C   . TYR D 4 57  ? 115.722 112.390 136.476 1.00 69.99  ? 57  TYR H C   1 
ATOM   9230  O O   . TYR D 4 57  ? 115.627 112.533 137.694 1.00 83.39  ? 57  TYR H O   1 
ATOM   9231  C CB  . TYR D 4 57  ? 115.505 110.048 136.047 1.00 96.92  ? 57  TYR H CB  1 
ATOM   9232  C CG  . TYR D 4 57  ? 114.326 110.295 135.110 1.00 73.54  ? 57  TYR H CG  1 
ATOM   9233  C CD1 . TYR D 4 57  ? 114.485 110.352 133.773 1.00 84.47  ? 57  TYR H CD1 1 
ATOM   9234  C CD2 . TYR D 4 57  ? 113.060 110.518 135.563 1.00 102.56 ? 57  TYR H CD2 1 
ATOM   9235  C CE1 . TYR D 4 57  ? 113.435 110.604 132.931 1.00 92.38  ? 57  TYR H CE1 1 
ATOM   9236  C CE2 . TYR D 4 57  ? 111.980 110.775 134.740 1.00 86.32  ? 57  TYR H CE2 1 
ATOM   9237  C CZ  . TYR D 4 57  ? 112.172 110.817 133.402 1.00 80.77  ? 57  TYR H CZ  1 
ATOM   9238  O OH  . TYR D 4 57  ? 111.263 111.029 132.433 1.00 93.81  ? 57  TYR H OH  1 
ATOM   9239  N N   . SER D 4 58  ? 115.162 113.203 135.550 1.00 59.73  ? 58  SER H N   1 
ATOM   9240  C CA  . SER D 4 58  ? 114.343 114.324 135.994 1.00 59.19  ? 58  SER H CA  1 
ATOM   9241  C C   . SER D 4 58  ? 113.230 114.620 135.004 1.00 43.94  ? 58  SER H C   1 
ATOM   9242  O O   . SER D 4 58  ? 113.361 114.349 133.835 1.00 69.59  ? 58  SER H O   1 
ATOM   9243  C CB  . SER D 4 58  ? 115.191 115.503 136.259 1.00 82.05  ? 58  SER H CB  1 
ATOM   9244  O OG  . SER D 4 58  ? 116.015 115.801 135.133 1.00 118.98 ? 58  SER H OG  1 
ATOM   9245  N N   . TYR D 4 59  ? 112.142 115.169 135.509 1.00 41.78  ? 59  TYR H N   1 
ATOM   9246  C CA  . TYR D 4 59  ? 110.835 115.173 134.870 1.00 42.11  ? 59  TYR H CA  1 
ATOM   9247  C C   . TYR D 4 59  ? 110.344 116.593 135.057 1.00 55.56  ? 59  TYR H C   1 
ATOM   9248  O O   . TYR D 4 59  ? 110.396 117.107 136.210 1.00 69.58  ? 59  TYR H O   1 
ATOM   9249  C CB  . TYR D 4 59  ? 109.900 114.125 135.534 1.00 38.30  ? 59  TYR H CB  1 
ATOM   9250  C CG  . TYR D 4 59  ? 108.613 113.958 134.775 1.00 47.32  ? 59  TYR H CG  1 
ATOM   9251  C CD1 . TYR D 4 59  ? 108.542 113.062 133.766 1.00 61.12  ? 59  TYR H CD1 1 
ATOM   9252  C CD2 . TYR D 4 59  ? 107.447 114.709 135.011 1.00 62.91  ? 59  TYR H CD2 1 
ATOM   9253  C CE1 . TYR D 4 59  ? 107.378 112.922 133.011 1.00 91.11  ? 59  TYR H CE1 1 
ATOM   9254  C CE2 . TYR D 4 59  ? 106.280 114.579 134.281 1.00 62.47  ? 59  TYR H CE2 1 
ATOM   9255  C CZ  . TYR D 4 59  ? 106.240 113.675 133.258 1.00 67.07  ? 59  TYR H CZ  1 
ATOM   9256  O OH  . TYR D 4 59  ? 105.112 113.513 132.532 1.00 83.48  ? 59  TYR H OH  1 
ATOM   9257  N N   . TYR D 4 60  ? 109.877 117.255 133.986 1.00 46.37  ? 60  TYR H N   1 
ATOM   9258  C CA  . TYR D 4 60  ? 109.659 118.701 134.130 1.00 59.30  ? 60  TYR H CA  1 
ATOM   9259  C C   . TYR D 4 60  ? 108.302 119.136 133.626 1.00 66.83  ? 60  TYR H C   1 
ATOM   9260  O O   . TYR D 4 60  ? 107.762 118.456 132.747 1.00 78.36  ? 60  TYR H O   1 
ATOM   9261  C CB  . TYR D 4 60  ? 110.586 119.568 133.308 1.00 55.98  ? 60  TYR H CB  1 
ATOM   9262  C CG  . TYR D 4 60  ? 112.044 119.310 133.550 1.00 66.19  ? 60  TYR H CG  1 
ATOM   9263  C CD1 . TYR D 4 60  ? 112.635 119.873 134.641 1.00 85.00  ? 60  TYR H CD1 1 
ATOM   9264  C CD2 . TYR D 4 60  ? 112.809 118.535 132.715 1.00 82.51  ? 60  TYR H CD2 1 
ATOM   9265  C CE1 . TYR D 4 60  ? 113.975 119.681 134.926 1.00 72.77  ? 60  TYR H CE1 1 
ATOM   9266  C CE2 . TYR D 4 60  ? 114.130 118.338 132.984 1.00 120.07 ? 60  TYR H CE2 1 
ATOM   9267  C CZ  . TYR D 4 60  ? 114.708 118.886 134.100 1.00 82.95  ? 60  TYR H CZ  1 
ATOM   9268  O OH  . TYR D 4 60  ? 116.019 118.616 134.226 1.00 108.82 ? 60  TYR H OH  1 
ATOM   9269  N N   . SER D 4 61  ? 107.769 120.249 134.155 1.00 50.45  ? 61  SER H N   1 
ATOM   9270  C CA  . SER D 4 61  ? 106.469 120.659 133.654 1.00 73.39  ? 61  SER H CA  1 
ATOM   9271  C C   . SER D 4 61  ? 106.648 121.135 132.222 1.00 103.42 ? 61  SER H C   1 
ATOM   9272  O O   . SER D 4 61  ? 107.730 121.491 131.857 1.00 81.53  ? 61  SER H O   1 
ATOM   9273  C CB  . SER D 4 61  ? 105.757 121.705 134.497 1.00 103.81 ? 61  SER H CB  1 
ATOM   9274  O OG  . SER D 4 61  ? 106.553 122.815 134.811 1.00 96.14  ? 61  SER H OG  1 
ATOM   9275  N N   . GLN D 4 62  ? 105.586 121.148 131.429 1.00 136.06 ? 62  GLN H N   1 
ATOM   9276  C CA  . GLN D 4 62  ? 105.700 121.549 130.034 1.00 127.79 ? 62  GLN H CA  1 
ATOM   9277  C C   . GLN D 4 62  ? 106.237 122.976 129.887 1.00 134.08 ? 62  GLN H C   1 
ATOM   9278  O O   . GLN D 4 62  ? 106.946 123.287 128.921 1.00 156.67 ? 62  GLN H O   1 
ATOM   9279  C CB  . GLN D 4 62  ? 104.315 121.410 129.398 1.00 151.30 ? 62  GLN H CB  1 
ATOM   9280  C CG  . GLN D 4 62  ? 104.368 121.226 127.892 1.00 206.99 ? 62  GLN H CG  1 
ATOM   9281  C CD  . GLN D 4 62  ? 104.953 119.882 127.534 1.00 226.01 ? 62  GLN H CD  1 
ATOM   9282  O OE1 . GLN D 4 62  ? 106.168 119.757 127.417 1.00 113.65 ? 62  GLN H OE1 1 
ATOM   9283  N NE2 . GLN D 4 62  ? 104.087 118.887 127.368 1.00 276.74 ? 62  GLN H NE2 1 
ATOM   9284  N N   . ASN D 4 63  ? 105.900 123.862 130.842 1.00 123.67 ? 63  ASN H N   1 
ATOM   9285  C CA  . ASN D 4 63  ? 106.315 125.258 130.809 1.00 124.54 ? 63  ASN H CA  1 
ATOM   9286  C C   . ASN D 4 63  ? 107.816 125.440 130.991 1.00 94.43  ? 63  ASN H C   1 
ATOM   9287  O O   . ASN D 4 63  ? 108.332 126.468 130.550 1.00 166.03 ? 63  ASN H O   1 
ATOM   9288  C CB  . ASN D 4 63  ? 105.647 126.140 131.865 1.00 153.24 ? 63  ASN H CB  1 
ATOM   9289  C CG  . ASN D 4 63  ? 104.139 126.182 131.745 1.00 223.32 ? 63  ASN H CG  1 
ATOM   9290  O OD1 . ASN D 4 63  ? 103.589 125.851 130.695 1.00 214.93 ? 63  ASN H OD1 1 
ATOM   9291  N ND2 . ASN D 4 63  ? 103.469 126.588 132.815 1.00 298.83 ? 63  ASN H ND2 1 
ATOM   9292  N N   . PHE D 4 64  ? 108.501 124.482 131.590 1.00 68.47  ? 64  PHE H N   1 
ATOM   9293  C CA  . PHE D 4 64  ? 109.915 124.627 131.905 1.00 84.02  ? 64  PHE H CA  1 
ATOM   9294  C C   . PHE D 4 64  ? 110.817 123.740 131.041 1.00 100.63 ? 64  PHE H C   1 
ATOM   9295  O O   . PHE D 4 64  ? 112.032 123.752 131.226 1.00 160.16 ? 64  PHE H O   1 
ATOM   9296  C CB  . PHE D 4 64  ? 110.171 124.363 133.398 1.00 83.91  ? 64  PHE H CB  1 
ATOM   9297  C CG  . PHE D 4 64  ? 109.648 125.490 134.237 1.00 75.62  ? 64  PHE H CG  1 
ATOM   9298  C CD1 . PHE D 4 64  ? 108.316 125.613 134.446 1.00 103.50 ? 64  PHE H CD1 1 
ATOM   9299  C CD2 . PHE D 4 64  ? 110.474 126.430 134.758 1.00 116.24 ? 64  PHE H CD2 1 
ATOM   9300  C CE1 . PHE D 4 64  ? 107.794 126.648 135.163 1.00 134.63 ? 64  PHE H CE1 1 
ATOM   9301  C CE2 . PHE D 4 64  ? 109.954 127.476 135.479 1.00 120.20 ? 64  PHE H CE2 1 
ATOM   9302  C CZ  . PHE D 4 64  ? 108.622 127.568 135.681 1.00 116.77 ? 64  PHE H CZ  1 
ATOM   9303  N N   . LYS D 4 65  ? 110.271 122.997 130.090 1.00 101.28 ? 65  LYS H N   1 
ATOM   9304  C CA  . LYS D 4 65  ? 111.031 121.915 129.505 1.00 139.10 ? 65  LYS H CA  1 
ATOM   9305  C C   . LYS D 4 65  ? 112.105 122.568 128.640 1.00 160.75 ? 65  LYS H C   1 
ATOM   9306  O O   . LYS D 4 65  ? 111.783 123.341 127.744 1.00 148.75 ? 65  LYS H O   1 
ATOM   9307  C CB  . LYS D 4 65  ? 110.059 120.977 128.789 1.00 125.20 ? 65  LYS H CB  1 
ATOM   9308  C CG  . LYS D 4 65  ? 110.667 119.645 128.446 1.00 166.98 ? 65  LYS H CG  1 
ATOM   9309  C CD  . LYS D 4 65  ? 109.677 118.701 127.823 1.00 191.16 ? 65  LYS H CD  1 
ATOM   9310  C CE  . LYS D 4 65  ? 108.600 118.173 128.747 1.00 150.72 ? 65  LYS H CE  1 
ATOM   9311  N NZ  . LYS D 4 65  ? 107.655 117.315 127.979 1.00 126.54 ? 65  LYS H NZ  1 
ATOM   9312  N N   . GLY D 4 66  ? 113.370 122.265 128.933 1.00 177.96 ? 66  GLY H N   1 
ATOM   9313  C CA  . GLY D 4 66  ? 114.476 122.901 128.232 1.00 213.78 ? 66  GLY H CA  1 
ATOM   9314  C C   . GLY D 4 66  ? 114.904 124.259 128.791 1.00 166.57 ? 66  GLY H C   1 
ATOM   9315  O O   . GLY D 4 66  ? 116.094 124.544 128.714 1.00 202.43 ? 66  GLY H O   1 
ATOM   9316  N N   . LYS D 4 67  ? 113.964 125.064 129.318 1.00 124.69 ? 67  LYS H N   1 
ATOM   9317  C CA  . LYS D 4 67  ? 114.259 126.263 130.110 1.00 135.84 ? 67  LYS H CA  1 
ATOM   9318  C C   . LYS D 4 67  ? 114.967 125.975 131.453 1.00 122.45 ? 67  LYS H C   1 
ATOM   9319  O O   . LYS D 4 67  ? 115.864 126.709 131.829 1.00 177.99 ? 67  LYS H O   1 
ATOM   9320  C CB  . LYS D 4 67  ? 112.963 127.052 130.350 1.00 179.66 ? 67  LYS H CB  1 
ATOM   9321  C CG  . LYS D 4 67  ? 113.103 128.351 131.162 1.00 175.88 ? 67  LYS H CG  1 
ATOM   9322  C CD  . LYS D 4 67  ? 111.816 129.057 131.531 1.00 253.64 ? 67  LYS H CD  1 
ATOM   9323  C CE  . LYS D 4 67  ? 111.059 129.643 130.350 1.00 363.34 ? 67  LYS H CE  1 
ATOM   9324  N NZ  . LYS D 4 67  ? 110.204 128.680 129.600 1.00 377.43 ? 67  LYS H NZ  1 
ATOM   9325  N N   . ALA D 4 68  ? 114.573 124.913 132.170 1.00 155.90 ? 68  ALA H N   1 
ATOM   9326  C CA  . ALA D 4 68  ? 115.198 124.454 133.398 1.00 119.26 ? 68  ALA H CA  1 
ATOM   9327  C C   . ALA D 4 68  ? 116.123 123.276 133.139 1.00 104.74 ? 68  ALA H C   1 
ATOM   9328  O O   . ALA D 4 68  ? 116.144 122.740 132.014 1.00 152.39 ? 68  ALA H O   1 
ATOM   9329  C CB  . ALA D 4 68  ? 114.133 123.971 134.316 1.00 146.83 ? 68  ALA H CB  1 
ATOM   9330  N N   . THR D 4 69  ? 116.852 122.897 134.199 1.00 73.31  ? 69  THR H N   1 
ATOM   9331  C CA  . THR D 4 69  ? 117.745 121.752 134.172 1.00 100.94 ? 69  THR H CA  1 
ATOM   9332  C C   . THR D 4 69  ? 118.168 121.399 135.591 1.00 93.61  ? 69  THR H C   1 
ATOM   9333  O O   . THR D 4 69  ? 118.934 122.160 136.217 1.00 158.06 ? 69  THR H O   1 
ATOM   9334  C CB  . THR D 4 69  ? 119.020 121.985 133.342 1.00 162.60 ? 69  THR H CB  1 
ATOM   9335  O OG1 . THR D 4 69  ? 118.756 122.248 131.957 1.00 190.77 ? 69  THR H OG1 1 
ATOM   9336  C CG2 . THR D 4 69  ? 119.972 120.801 133.428 1.00 180.06 ? 69  THR H CG2 1 
ATOM   9337  N N   . LEU D 4 70  ? 117.680 120.253 136.077 1.00 92.02  ? 70  LEU H N   1 
ATOM   9338  C CA  . LEU D 4 70  ? 117.982 119.778 137.421 1.00 113.91 ? 70  LEU H CA  1 
ATOM   9339  C C   . LEU D 4 70  ? 119.144 118.839 137.331 1.00 103.68 ? 70  LEU H C   1 
ATOM   9340  O O   . LEU D 4 70  ? 119.236 118.046 136.404 1.00 160.83 ? 70  LEU H O   1 
ATOM   9341  C CB  . LEU D 4 70  ? 116.817 119.016 138.046 1.00 100.25 ? 70  LEU H CB  1 
ATOM   9342  C CG  . LEU D 4 70  ? 115.779 119.828 138.812 1.00 95.91  ? 70  LEU H CG  1 
ATOM   9343  C CD1 . LEU D 4 70  ? 115.565 121.171 138.215 1.00 108.17 ? 70  LEU H CD1 1 
ATOM   9344  C CD2 . LEU D 4 70  ? 114.429 119.121 138.825 1.00 105.06 ? 70  LEU H CD2 1 
ATOM   9345  N N   . THR D 4 71  ? 120.027 118.943 138.313 1.00 100.13 ? 71  THR H N   1 
ATOM   9346  C CA  . THR D 4 71  ? 121.010 117.898 138.560 1.00 108.46 ? 71  THR H CA  1 
ATOM   9347  C C   . THR D 4 71  ? 121.074 117.710 140.059 1.00 98.12  ? 71  THR H C   1 
ATOM   9348  O O   . THR D 4 71  ? 120.241 118.308 140.798 1.00 91.21  ? 71  THR H O   1 
ATOM   9349  C CB  . THR D 4 71  ? 122.380 118.223 137.945 1.00 143.77 ? 71  THR H CB  1 
ATOM   9350  O OG1 . THR D 4 71  ? 122.912 119.428 138.498 1.00 184.91 ? 71  THR H OG1 1 
ATOM   9351  C CG2 . THR D 4 71  ? 122.308 118.416 136.447 1.00 264.10 ? 71  THR H CG2 1 
ATOM   9352  N N   . VAL D 4 72  ? 122.078 116.907 140.440 1.00 74.67  ? 72  VAL H N   1 
ATOM   9353  C CA  . VAL D 4 72  ? 122.201 116.483 141.809 1.00 87.40  ? 72  VAL H CA  1 
ATOM   9354  C C   . VAL D 4 72  ? 123.653 116.059 142.070 1.00 130.01 ? 72  VAL H C   1 
ATOM   9355  O O   . VAL D 4 72  ? 124.397 115.713 141.143 1.00 196.03 ? 72  VAL H O   1 
ATOM   9356  C CB  . VAL D 4 72  ? 121.150 115.364 142.010 1.00 98.13  ? 72  VAL H CB  1 
ATOM   9357  C CG1 . VAL D 4 72  ? 121.579 114.061 141.329 1.00 172.68 ? 72  VAL H CG1 1 
ATOM   9358  C CG2 . VAL D 4 72  ? 120.806 115.114 143.441 1.00 73.12  ? 72  VAL H CG2 1 
ATOM   9359  N N   . ASP D 4 73  ? 124.046 116.094 143.350 1.00 150.91 ? 73  ASP H N   1 
ATOM   9360  C CA  . ASP D 4 73  ? 125.366 115.687 143.823 1.00 156.27 ? 73  ASP H CA  1 
ATOM   9361  C C   . ASP D 4 73  ? 125.194 114.828 145.083 1.00 151.61 ? 73  ASP H C   1 
ATOM   9362  O O   . ASP D 4 73  ? 124.962 115.353 146.195 1.00 143.56 ? 73  ASP H O   1 
ATOM   9363  C CB  . ASP D 4 73  ? 126.250 116.907 144.107 1.00 225.56 ? 73  ASP H CB  1 
ATOM   9364  C CG  . ASP D 4 73  ? 127.446 116.637 145.016 1.00 259.42 ? 73  ASP H CG  1 
ATOM   9365  O OD1 . ASP D 4 73  ? 127.949 115.497 145.015 1.00 267.82 ? 73  ASP H OD1 1 
ATOM   9366  O OD2 . ASP D 4 73  ? 127.850 117.562 145.742 1.00 213.48 ? 73  ASP H OD2 1 
ATOM   9367  N N   . GLN D 4 74  ? 125.322 113.504 144.893 1.00 144.16 ? 74  GLN H N   1 
ATOM   9368  C CA  . GLN D 4 74  ? 125.087 112.541 145.965 1.00 169.56 ? 74  GLN H CA  1 
ATOM   9369  C C   . GLN D 4 74  ? 126.151 112.627 147.054 1.00 202.03 ? 74  GLN H C   1 
ATOM   9370  O O   . GLN D 4 74  ? 125.912 112.152 148.165 1.00 230.85 ? 74  GLN H O   1 
ATOM   9371  C CB  . GLN D 4 74  ? 125.036 111.118 145.399 1.00 169.11 ? 74  GLN H CB  1 
ATOM   9372  C CG  . GLN D 4 74  ? 123.824 110.906 144.505 1.00 201.74 ? 74  GLN H CG  1 
ATOM   9373  C CD  . GLN D 4 74  ? 124.095 110.046 143.301 1.00 261.94 ? 74  GLN H CD  1 
ATOM   9374  O OE1 . GLN D 4 74  ? 124.293 110.532 142.183 1.00 278.45 ? 74  GLN H OE1 1 
ATOM   9375  N NE2 . GLN D 4 74  ? 124.098 108.744 143.534 1.00 287.51 ? 74  GLN H NE2 1 
ATOM   9376  N N   . SER D 4 75  ? 127.319 113.212 146.740 1.00 200.85 ? 75  SER H N   1 
ATOM   9377  C CA  . SER D 4 75  ? 128.420 113.278 147.689 1.00 222.41 ? 75  SER H CA  1 
ATOM   9378  C C   . SER D 4 75  ? 128.154 114.295 148.804 1.00 202.04 ? 75  SER H C   1 
ATOM   9379  O O   . SER D 4 75  ? 128.795 114.195 149.852 1.00 198.02 ? 75  SER H O   1 
ATOM   9380  C CB  . SER D 4 75  ? 129.728 113.537 146.968 1.00 258.62 ? 75  SER H CB  1 
ATOM   9381  O OG  . SER D 4 75  ? 129.862 114.896 146.583 1.00 251.27 ? 75  SER H OG  1 
ATOM   9382  N N   . SER D 4 76  ? 127.225 115.249 148.593 1.00 189.25 ? 76  SER H N   1 
ATOM   9383  C CA  . SER D 4 76  ? 126.928 116.294 149.566 1.00 197.09 ? 76  SER H CA  1 
ATOM   9384  C C   . SER D 4 76  ? 125.436 116.406 149.936 1.00 165.34 ? 76  SER H C   1 
ATOM   9385  O O   . SER D 4 76  ? 125.084 117.297 150.714 1.00 132.21 ? 76  SER H O   1 
ATOM   9386  C CB  . SER D 4 76  ? 127.471 117.599 149.053 1.00 159.61 ? 76  SER H CB  1 
ATOM   9387  O OG  . SER D 4 76  ? 126.702 118.077 147.972 1.00 151.12 ? 76  SER H OG  1 
ATOM   9388  N N   . ASN D 4 77  ? 124.581 115.515 149.402 1.00 113.40 ? 77  ASN H N   1 
ATOM   9389  C CA  . ASN D 4 77  ? 123.151 115.632 149.507 1.00 90.47  ? 77  ASN H CA  1 
ATOM   9390  C C   . ASN D 4 77  ? 122.669 116.968 148.933 1.00 88.42  ? 77  ASN H C   1 
ATOM   9391  O O   . ASN D 4 77  ? 121.738 117.569 149.476 1.00 116.65 ? 77  ASN H O   1 
ATOM   9392  C CB  . ASN D 4 77  ? 122.654 115.474 150.949 1.00 123.29 ? 77  ASN H CB  1 
ATOM   9393  C CG  . ASN D 4 77  ? 123.173 114.267 151.699 1.00 163.16 ? 77  ASN H CG  1 
ATOM   9394  O OD1 . ASN D 4 77  ? 123.604 113.285 151.097 1.00 128.77 ? 77  ASN H OD1 1 
ATOM   9395  N ND2 . ASN D 4 77  ? 123.094 114.342 153.022 1.00 224.92 ? 77  ASN H ND2 1 
ATOM   9396  N N   . THR D 4 78  ? 123.233 117.430 147.824 1.00 81.60  ? 78  THR H N   1 
ATOM   9397  C CA  . THR D 4 78  ? 122.780 118.686 147.254 1.00 108.38 ? 78  THR H CA  1 
ATOM   9398  C C   . THR D 4 78  ? 122.080 118.450 145.918 1.00 103.06 ? 78  THR H C   1 
ATOM   9399  O O   . THR D 4 78  ? 122.530 117.652 145.113 1.00 129.82 ? 78  THR H O   1 
ATOM   9400  C CB  . THR D 4 78  ? 123.925 119.680 147.028 1.00 160.08 ? 78  THR H CB  1 
ATOM   9401  O OG1 . THR D 4 78  ? 124.662 119.902 148.228 1.00 178.19 ? 78  THR H OG1 1 
ATOM   9402  C CG2 . THR D 4 78  ? 123.472 121.019 146.473 1.00 164.14 ? 78  THR H CG2 1 
ATOM   9403  N N   . ALA D 4 79  ? 120.977 119.175 145.718 1.00 118.96 ? 79  ALA H N   1 
ATOM   9404  C CA  . ALA D 4 79  ? 120.241 119.259 144.480 1.00 96.89  ? 79  ALA H CA  1 
ATOM   9405  C C   . ALA D 4 79  ? 120.396 120.649 143.892 1.00 80.75  ? 79  ALA H C   1 
ATOM   9406  O O   . ALA D 4 79  ? 120.383 121.629 144.611 1.00 105.21 ? 79  ALA H O   1 
ATOM   9407  C CB  . ALA D 4 79  ? 118.824 118.957 144.835 1.00 109.23 ? 79  ALA H CB  1 
ATOM   9408  N N   . TYR D 4 80  ? 120.534 120.763 142.583 1.00 90.50  ? 80  TYR H N   1 
ATOM   9409  C CA  . TYR D 4 80  ? 120.822 122.034 141.927 1.00 100.47 ? 80  TYR H CA  1 
ATOM   9410  C C   . TYR D 4 80  ? 119.835 122.242 140.802 1.00 78.07  ? 80  TYR H C   1 
ATOM   9411  O O   . TYR D 4 80  ? 119.652 121.345 139.965 1.00 160.22 ? 80  TYR H O   1 
ATOM   9412  C CB  . TYR D 4 80  ? 122.191 122.038 141.239 1.00 157.44 ? 80  TYR H CB  1 
ATOM   9413  C CG  . TYR D 4 80  ? 123.377 121.880 142.169 1.00 166.44 ? 80  TYR H CG  1 
ATOM   9414  C CD1 . TYR D 4 80  ? 123.914 122.985 142.787 1.00 172.80 ? 80  TYR H CD1 1 
ATOM   9415  C CD2 . TYR D 4 80  ? 123.941 120.634 142.420 1.00 178.51 ? 80  TYR H CD2 1 
ATOM   9416  C CE1 . TYR D 4 80  ? 125.012 122.875 143.624 1.00 191.61 ? 80  TYR H CE1 1 
ATOM   9417  C CE2 . TYR D 4 80  ? 125.036 120.505 143.255 1.00 190.39 ? 80  TYR H CE2 1 
ATOM   9418  C CZ  . TYR D 4 80  ? 125.574 121.633 143.861 1.00 203.29 ? 80  TYR H CZ  1 
ATOM   9419  O OH  . TYR D 4 80  ? 126.654 121.549 144.704 1.00 258.53 ? 80  TYR H OH  1 
ATOM   9420  N N   . LEU D 4 81  ? 119.207 123.406 140.790 1.00 77.70  ? 81  LEU H N   1 
ATOM   9421  C CA  . LEU D 4 81  ? 118.361 123.784 139.662 1.00 88.20  ? 81  LEU H CA  1 
ATOM   9422  C C   . LEU D 4 81  ? 119.092 124.851 138.875 1.00 72.23  ? 81  LEU H C   1 
ATOM   9423  O O   . LEU D 4 81  ? 119.273 125.964 139.433 1.00 93.13  ? 81  LEU H O   1 
ATOM   9424  C CB  . LEU D 4 81  ? 116.993 124.245 140.194 1.00 84.81  ? 81  LEU H CB  1 
ATOM   9425  C CG  . LEU D 4 81  ? 116.176 125.151 139.301 1.00 80.75  ? 81  LEU H CG  1 
ATOM   9426  C CD1 . LEU D 4 81  ? 115.808 124.475 138.013 1.00 74.92  ? 81  LEU H CD1 1 
ATOM   9427  C CD2 . LEU D 4 81  ? 114.951 125.625 140.029 1.00 85.59  ? 81  LEU H CD2 1 
ATOM   9428  N N   . GLN D 4 82  ? 119.524 124.505 137.642 1.00 110.66 ? 82  GLN H N   1 
ATOM   9429  C CA  . GLN D 4 82  ? 119.888 125.542 136.681 1.00 143.79 ? 82  GLN H CA  1 
ATOM   9430  C C   . GLN D 4 82  ? 118.651 126.066 136.004 1.00 98.65  ? 82  GLN H C   1 
ATOM   9431  O O   . GLN D 4 82  ? 117.801 125.307 135.593 1.00 132.05 ? 82  GLN H O   1 
ATOM   9432  C CB  . GLN D 4 82  ? 120.724 125.143 135.459 1.00 150.98 ? 82  GLN H CB  1 
ATOM   9433  C CG  . GLN D 4 82  ? 122.096 124.612 135.808 1.00 223.26 ? 82  GLN H CG  1 
ATOM   9434  C CD  . GLN D 4 82  ? 123.062 124.840 134.657 1.00 271.47 ? 82  GLN H CD  1 
ATOM   9435  O OE1 . GLN D 4 82  ? 122.838 125.680 133.775 1.00 165.27 ? 82  GLN H OE1 1 
ATOM   9436  N NE2 . GLN D 4 82  ? 124.161 124.095 134.671 1.00 351.30 ? 82  GLN H NE2 1 
ATOM   9437  N N   . LEU D 4 83  ? 118.602 127.372 135.884 1.00 102.59 ? 83  LEU H N   1 
ATOM   9438  C CA  . LEU D 4 83  ? 117.592 128.015 135.088 1.00 110.19 ? 83  LEU H CA  1 
ATOM   9439  C C   . LEU D 4 83  ? 118.284 128.859 134.048 1.00 147.79 ? 83  LEU H C   1 
ATOM   9440  O O   . LEU D 4 83  ? 119.389 129.357 134.282 1.00 249.29 ? 83  LEU H O   1 
ATOM   9441  C CB  . LEU D 4 83  ? 116.753 128.869 136.023 1.00 137.53 ? 83  LEU H CB  1 
ATOM   9442  C CG  . LEU D 4 83  ? 115.394 128.302 136.356 1.00 165.67 ? 83  LEU H CG  1 
ATOM   9443  C CD1 . LEU D 4 83  ? 114.956 129.020 137.661 1.00 114.75 ? 83  LEU H CD1 1 
ATOM   9444  C CD2 . LEU D 4 83  ? 114.498 128.380 135.089 1.00 140.25 ? 83  LEU H CD2 1 
ATOM   9445  N N   . THR D 4 84  ? 117.639 129.013 132.884 1.00 174.84 ? 84  THR H N   1 
ATOM   9446  C CA  . THR D 4 84  ? 118.305 129.612 131.718 1.00 196.09 ? 84  THR H CA  1 
ATOM   9447  C C   . THR D 4 84  ? 117.347 130.554 130.983 1.00 161.46 ? 84  THR H C   1 
ATOM   9448  O O   . THR D 4 84  ? 116.132 130.406 131.092 1.00 261.56 ? 84  THR H O   1 
ATOM   9449  C CB  . THR D 4 84  ? 118.880 128.520 130.791 1.00 234.10 ? 84  THR H CB  1 
ATOM   9450  O OG1 . THR D 4 84  ? 117.788 127.897 130.124 1.00 219.53 ? 84  THR H OG1 1 
ATOM   9451  C CG2 . THR D 4 84  ? 119.706 127.463 131.508 1.00 241.39 ? 84  THR H CG2 1 
ATOM   9452  N N   . SER D 4 85  ? 117.903 131.514 130.240 1.00 158.42 ? 85  SER H N   1 
ATOM   9453  C CA  . SER D 4 85  ? 117.170 132.488 129.437 1.00 220.98 ? 85  SER H CA  1 
ATOM   9454  C C   . SER D 4 85  ? 116.246 133.401 130.266 1.00 206.23 ? 85  SER H C   1 
ATOM   9455  O O   . SER D 4 85  ? 115.237 133.899 129.749 1.00 208.94 ? 85  SER H O   1 
ATOM   9456  C CB  . SER D 4 85  ? 116.432 131.808 128.276 1.00 278.41 ? 85  SER H CB  1 
ATOM   9457  O OG  . SER D 4 85  ? 115.268 131.102 128.692 1.00 245.96 ? 85  SER H OG  1 
ATOM   9458  N N   . LEU D 4 86  ? 116.606 133.651 131.532 1.00 164.43 ? 86  LEU H N   1 
ATOM   9459  C CA  . LEU D 4 86  ? 115.750 134.369 132.486 1.00 154.23 ? 86  LEU H CA  1 
ATOM   9460  C C   . LEU D 4 86  ? 115.370 135.780 132.024 1.00 119.34 ? 86  LEU H C   1 
ATOM   9461  O O   . LEU D 4 86  ? 116.211 136.603 131.760 1.00 159.38 ? 86  LEU H O   1 
ATOM   9462  C CB  . LEU D 4 86  ? 116.427 134.443 133.859 1.00 142.65 ? 86  LEU H CB  1 
ATOM   9463  C CG  . LEU D 4 86  ? 116.457 133.137 134.650 1.00 191.88 ? 86  LEU H CG  1 
ATOM   9464  C CD1 . LEU D 4 86  ? 117.362 133.241 135.851 1.00 170.67 ? 86  LEU H CD1 1 
ATOM   9465  C CD2 . LEU D 4 86  ? 115.083 132.734 135.111 1.00 227.16 ? 86  LEU H CD2 1 
ATOM   9466  N N   . THR D 4 87  ? 114.064 136.038 131.943 1.00 145.41 ? 87  THR H N   1 
ATOM   9467  C CA  . THR D 4 87  ? 113.451 137.332 131.681 1.00 156.14 ? 87  THR H CA  1 
ATOM   9468  C C   . THR D 4 87  ? 113.053 138.000 133.002 1.00 120.45 ? 87  THR H C   1 
ATOM   9469  O O   . THR D 4 87  ? 113.125 137.372 134.042 1.00 117.30 ? 87  THR H O   1 
ATOM   9470  C CB  . THR D 4 87  ? 112.206 137.134 130.799 1.00 176.86 ? 87  THR H CB  1 
ATOM   9471  O OG1 . THR D 4 87  ? 111.222 136.439 131.564 1.00 213.71 ? 87  THR H OG1 1 
ATOM   9472  C CG2 . THR D 4 87  ? 112.478 136.343 129.534 1.00 199.90 ? 87  THR H CG2 1 
ATOM   9473  N N   . SER D 4 88  ? 112.598 139.256 132.967 1.00 166.19 ? 88  SER H N   1 
ATOM   9474  C CA  . SER D 4 88  ? 112.098 139.930 134.162 1.00 169.07 ? 88  SER H CA  1 
ATOM   9475  C C   . SER D 4 88  ? 110.913 139.164 134.740 1.00 168.08 ? 88  SER H C   1 
ATOM   9476  O O   . SER D 4 88  ? 110.837 139.033 135.964 1.00 237.65 ? 88  SER H O   1 
ATOM   9477  C CB  . SER D 4 88  ? 111.743 141.365 133.894 1.00 231.90 ? 88  SER H CB  1 
ATOM   9478  O OG  . SER D 4 88  ? 111.312 142.015 135.084 1.00 237.05 ? 88  SER H OG  1 
ATOM   9479  N N   . GLU D 4 89  ? 110.030 138.618 133.879 1.00 141.35 ? 89  GLU H N   1 
ATOM   9480  C CA  . GLU D 4 89  ? 108.905 137.822 134.380 1.00 183.34 ? 89  GLU H CA  1 
ATOM   9481  C C   . GLU D 4 89  ? 109.291 136.423 134.925 1.00 143.24 ? 89  GLU H C   1 
ATOM   9482  O O   . GLU D 4 89  ? 108.418 135.690 135.341 1.00 151.93 ? 89  GLU H O   1 
ATOM   9483  C CB  . GLU D 4 89  ? 107.809 137.716 133.307 1.00 210.83 ? 89  GLU H CB  1 
ATOM   9484  C CG  . GLU D 4 89  ? 108.144 136.838 132.103 1.00 272.16 ? 89  GLU H CG  1 
ATOM   9485  C CD  . GLU D 4 89  ? 106.984 136.135 131.411 1.00 378.79 ? 89  GLU H CD  1 
ATOM   9486  O OE1 . GLU D 4 89  ? 105.820 136.563 131.586 1.00 432.83 ? 89  GLU H OE1 1 
ATOM   9487  O OE2 . GLU D 4 89  ? 107.252 135.147 130.697 1.00 412.32 ? 89  GLU H OE2 1 
ATOM   9488  N N   . ASP D 4 90  ? 110.561 136.021 134.948 1.00 151.39 ? 90  ASP H N   1 
ATOM   9489  C CA  . ASP D 4 90  ? 111.051 134.846 135.667 1.00 114.77 ? 90  ASP H CA  1 
ATOM   9490  C C   . ASP D 4 90  ? 111.679 135.213 137.025 1.00 93.55  ? 90  ASP H C   1 
ATOM   9491  O O   . ASP D 4 90  ? 112.274 134.380 137.714 1.00 87.51  ? 90  ASP H O   1 
ATOM   9492  C CB  . ASP D 4 90  ? 112.044 134.087 134.769 1.00 180.10 ? 90  ASP H CB  1 
ATOM   9493  C CG  . ASP D 4 90  ? 111.482 133.602 133.426 1.00 266.10 ? 90  ASP H CG  1 
ATOM   9494  O OD1 . ASP D 4 90  ? 110.528 132.815 133.439 1.00 273.56 ? 90  ASP H OD1 1 
ATOM   9495  O OD2 . ASP D 4 90  ? 111.995 134.014 132.371 1.00 342.62 ? 90  ASP H OD2 1 
ATOM   9496  N N   . SER D 4 91  ? 111.538 136.475 137.450 1.00 131.61 ? 91  SER H N   1 
ATOM   9497  C CA  . SER D 4 91  ? 111.861 136.895 138.807 1.00 136.45 ? 91  SER H CA  1 
ATOM   9498  C C   . SER D 4 91  ? 110.817 136.277 139.699 1.00 141.05 ? 91  SER H C   1 
ATOM   9499  O O   . SER D 4 91  ? 109.643 136.361 139.350 1.00 140.74 ? 91  SER H O   1 
ATOM   9500  C CB  . SER D 4 91  ? 111.798 138.380 139.015 1.00 191.54 ? 91  SER H CB  1 
ATOM   9501  O OG  . SER D 4 91  ? 112.647 139.072 138.124 1.00 251.52 ? 91  SER H OG  1 
ATOM   9502  N N   . ALA D 4 92  ? 111.250 135.673 140.809 1.00 128.56 ? 92  ALA H N   1 
ATOM   9503  C CA  . ALA D 4 92  ? 110.366 134.890 141.666 1.00 110.05 ? 92  ALA H CA  1 
ATOM   9504  C C   . ALA D 4 92  ? 111.081 134.419 142.918 1.00 106.55 ? 92  ALA H C   1 
ATOM   9505  O O   . ALA D 4 92  ? 112.261 134.720 143.104 1.00 175.06 ? 92  ALA H O   1 
ATOM   9506  C CB  . ALA D 4 92  ? 109.897 133.686 140.921 1.00 113.69 ? 92  ALA H CB  1 
ATOM   9507  N N   . VAL D 4 93  ? 110.365 133.676 143.757 1.00 83.72  ? 93  VAL H N   1 
ATOM   9508  C CA  . VAL D 4 93  ? 111.013 132.861 144.759 1.00 86.07  ? 93  VAL H CA  1 
ATOM   9509  C C   . VAL D 4 93  ? 110.991 131.407 144.343 1.00 86.37  ? 93  VAL H C   1 
ATOM   9510  O O   . VAL D 4 93  ? 109.957 130.923 143.934 1.00 96.20  ? 93  VAL H O   1 
ATOM   9511  C CB  . VAL D 4 93  ? 110.274 132.916 146.076 1.00 91.45  ? 93  VAL H CB  1 
ATOM   9512  C CG1 . VAL D 4 93  ? 111.181 132.262 147.102 1.00 72.70  ? 93  VAL H CG1 1 
ATOM   9513  C CG2 . VAL D 4 93  ? 109.834 134.334 146.427 1.00 135.97 ? 93  VAL H CG2 1 
ATOM   9514  N N   . TYR D 4 94  ? 112.120 130.737 144.481 1.00 69.50  ? 94  TYR H N   1 
ATOM   9515  C CA  . TYR D 4 94  ? 112.267 129.362 144.071 1.00 74.02  ? 94  TYR H CA  1 
ATOM   9516  C C   . TYR D 4 94  ? 112.479 128.539 145.342 1.00 69.78  ? 94  TYR H C   1 
ATOM   9517  O O   . TYR D 4 94  ? 113.375 128.759 146.141 1.00 76.17  ? 94  TYR H O   1 
ATOM   9518  C CB  . TYR D 4 94  ? 113.415 129.205 143.056 1.00 76.85  ? 94  TYR H CB  1 
ATOM   9519  C CG  . TYR D 4 94  ? 113.075 129.897 141.739 1.00 62.61  ? 94  TYR H CG  1 
ATOM   9520  C CD1 . TYR D 4 94  ? 113.302 131.209 141.485 1.00 92.98  ? 94  TYR H CD1 1 
ATOM   9521  C CD2 . TYR D 4 94  ? 112.494 129.222 140.763 1.00 66.88  ? 94  TYR H CD2 1 
ATOM   9522  C CE1 . TYR D 4 94  ? 112.963 131.810 140.303 1.00 97.33  ? 94  TYR H CE1 1 
ATOM   9523  C CE2 . TYR D 4 94  ? 112.130 129.783 139.581 1.00 73.69  ? 94  TYR H CE2 1 
ATOM   9524  C CZ  . TYR D 4 94  ? 112.350 131.088 139.342 1.00 83.96  ? 94  TYR H CZ  1 
ATOM   9525  O OH  . TYR D 4 94  ? 111.999 131.620 138.148 1.00 134.33 ? 94  TYR H OH  1 
ATOM   9526  N N   . TYR D 4 95  ? 111.607 127.566 145.504 1.00 74.53  ? 95  TYR H N   1 
ATOM   9527  C CA  . TYR D 4 95  ? 111.579 126.710 146.650 1.00 65.45  ? 95  TYR H CA  1 
ATOM   9528  C C   . TYR D 4 95  ? 111.942 125.289 146.215 1.00 71.13  ? 95  TYR H C   1 
ATOM   9529  O O   . TYR D 4 95  ? 111.473 124.736 145.219 1.00 43.49  ? 95  TYR H O   1 
ATOM   9530  C CB  . TYR D 4 95  ? 110.153 126.689 147.200 1.00 65.96  ? 95  TYR H CB  1 
ATOM   9531  C CG  . TYR D 4 95  ? 109.612 127.923 147.889 1.00 51.21  ? 95  TYR H CG  1 
ATOM   9532  C CD1 . TYR D 4 95  ? 109.935 128.206 149.168 1.00 51.51  ? 95  TYR H CD1 1 
ATOM   9533  C CD2 . TYR D 4 95  ? 108.780 128.793 147.267 1.00 81.49  ? 95  TYR H CD2 1 
ATOM   9534  C CE1 . TYR D 4 95  ? 109.476 129.322 149.831 1.00 73.94  ? 95  TYR H CE1 1 
ATOM   9535  C CE2 . TYR D 4 95  ? 108.284 129.916 147.897 1.00 98.93  ? 95  TYR H CE2 1 
ATOM   9536  C CZ  . TYR D 4 95  ? 108.638 130.200 149.201 1.00 103.05 ? 95  TYR H CZ  1 
ATOM   9537  O OH  . TYR D 4 95  ? 108.219 131.297 149.920 1.00 133.59 ? 95  TYR H OH  1 
ATOM   9538  N N   . CYS D 4 96  ? 112.809 124.706 147.032 1.00 85.84  ? 96  CYS H N   1 
ATOM   9539  C CA  . CYS D 4 96  ? 113.179 123.311 146.987 1.00 68.61  ? 96  CYS H CA  1 
ATOM   9540  C C   . CYS D 4 96  ? 112.254 122.588 147.957 1.00 67.31  ? 96  CYS H C   1 
ATOM   9541  O O   . CYS D 4 96  ? 112.115 123.019 149.092 1.00 92.83  ? 96  CYS H O   1 
ATOM   9542  C CB  . CYS D 4 96  ? 114.613 123.245 147.461 1.00 78.41  ? 96  CYS H CB  1 
ATOM   9543  S SG  . CYS D 4 96  ? 115.319 121.603 147.574 1.00 154.37 ? 96  CYS H SG  1 
ATOM   9544  N N   . ALA D 4 97  ? 111.670 121.461 147.544 1.00 71.57  ? 97  ALA H N   1 
ATOM   9545  C CA  . ALA D 4 97  ? 110.717 120.694 148.335 1.00 57.62  ? 97  ALA H CA  1 
ATOM   9546  C C   . ALA D 4 97  ? 110.960 119.181 148.206 1.00 54.97  ? 97  ALA H C   1 
ATOM   9547  O O   . ALA D 4 97  ? 111.465 118.693 147.206 1.00 61.59  ? 97  ALA H O   1 
ATOM   9548  C CB  . ALA D 4 97  ? 109.359 121.032 147.826 1.00 83.89  ? 97  ALA H CB  1 
ATOM   9549  N N   . ARG D 4 98  ? 110.631 118.422 149.252 1.00 58.70  ? 98  ARG H N   1 
ATOM   9550  C CA  . ARG D 4 98  ? 110.785 116.972 149.324 1.00 51.13  ? 98  ARG H CA  1 
ATOM   9551  C C   . ARG D 4 98  ? 109.435 116.287 149.410 1.00 47.25  ? 98  ARG H C   1 
ATOM   9552  O O   . ARG D 4 98  ? 108.476 116.797 149.976 1.00 58.72  ? 98  ARG H O   1 
ATOM   9553  C CB  . ARG D 4 98  ? 111.559 116.557 150.570 1.00 53.29  ? 98  ARG H CB  1 
ATOM   9554  C CG  . ARG D 4 98  ? 112.355 115.297 150.327 1.00 73.93  ? 98  ARG H CG  1 
ATOM   9555  C CD  . ARG D 4 98  ? 112.655 114.442 151.537 1.00 73.50  ? 98  ARG H CD  1 
ATOM   9556  N NE  . ARG D 4 98  ? 111.511 113.698 151.909 1.00 59.30  ? 98  ARG H NE  1 
ATOM   9557  C CZ  . ARG D 4 98  ? 111.461 112.952 152.968 1.00 90.60  ? 98  ARG H CZ  1 
ATOM   9558  N NH1 . ARG D 4 98  ? 110.394 112.207 153.246 1.00 115.97 ? 98  ARG H NH1 1 
ATOM   9559  N NH2 . ARG D 4 98  ? 112.490 112.956 153.776 1.00 96.20  ? 98  ARG H NH2 1 
ATOM   9560  N N   . GLY D 4 99  ? 109.326 115.123 148.811 1.00 59.95  ? 99  GLY H N   1 
ATOM   9561  C CA  . GLY D 4 99  ? 108.082 114.399 148.889 1.00 83.48  ? 99  GLY H CA  1 
ATOM   9562  C C   . GLY D 4 99  ? 107.949 113.610 150.189 1.00 72.58  ? 99  GLY H C   1 
ATOM   9563  O O   . GLY D 4 99  ? 108.926 113.406 150.893 1.00 64.46  ? 99  GLY H O   1 
ATOM   9564  N N   . ARG D 4 100 ? 106.746 113.122 150.448 1.00 72.34  ? 100 ARG H N   1 
ATOM   9565  C CA  . ARG D 4 100 ? 106.559 112.185 151.523 1.00 77.09  ? 100 ARG H CA  1 
ATOM   9566  C C   . ARG D 4 100 ? 106.849 110.757 151.056 1.00 88.20  ? 100 ARG H C   1 
ATOM   9567  O O   . ARG D 4 100 ? 107.753 110.151 151.585 1.00 95.79  ? 100 ARG H O   1 
ATOM   9568  C CB  . ARG D 4 100 ? 105.159 112.382 152.137 1.00 101.67 ? 100 ARG H CB  1 
ATOM   9569  C CG  . ARG D 4 100 ? 104.959 111.567 153.414 1.00 117.69 ? 100 ARG H CG  1 
ATOM   9570  C CD  . ARG D 4 100 ? 106.170 111.718 154.366 1.00 126.61 ? 100 ARG H CD  1 
ATOM   9571  N NE  . ARG D 4 100 ? 105.834 111.811 155.762 1.00 145.00 ? 100 ARG H NE  1 
ATOM   9572  C CZ  . ARG D 4 100 ? 105.174 112.811 156.352 1.00 183.15 ? 100 ARG H CZ  1 
ATOM   9573  N NH1 . ARG D 4 100 ? 104.439 112.557 157.418 1.00 293.29 ? 100 ARG H NH1 1 
ATOM   9574  N NH2 . ARG D 4 100 ? 105.191 114.045 155.899 1.00 127.11 ? 100 ARG H NH2 1 
ATOM   9575  N N   . GLN D 4 101 ? 106.060 110.234 150.113 1.00 93.11  ? 101 GLN H N   1 
ATOM   9576  C CA  . GLN D 4 101 ? 106.347 108.986 149.421 1.00 87.69  ? 101 GLN H CA  1 
ATOM   9577  C C   . GLN D 4 101 ? 107.380 109.298 148.352 1.00 100.87 ? 101 GLN H C   1 
ATOM   9578  O O   . GLN D 4 101 ? 107.550 110.455 147.983 1.00 95.13  ? 101 GLN H O   1 
ATOM   9579  C CB  . GLN D 4 101 ? 105.114 108.414 148.690 1.00 142.51 ? 101 GLN H CB  1 
ATOM   9580  C CG  . GLN D 4 101 ? 104.422 107.270 149.413 1.00 116.38 ? 101 GLN H CG  1 
ATOM   9581  C CD  . GLN D 4 101 ? 105.184 105.998 149.171 1.00 212.32 ? 101 GLN H CD  1 
ATOM   9582  O OE1 . GLN D 4 101 ? 106.390 106.001 148.941 1.00 226.94 ? 101 GLN H OE1 1 
ATOM   9583  N NE2 . GLN D 4 101 ? 104.477 104.878 149.232 1.00 314.22 ? 101 GLN H NE2 1 
ATOM   9584  N N   . THR D 4 102 ? 108.046 108.254 147.836 1.00 112.80 ? 102 THR H N   1 
ATOM   9585  C CA  . THR D 4 102 ? 109.238 108.372 146.992 1.00 90.06  ? 102 THR H CA  1 
ATOM   9586  C C   . THR D 4 102 ? 108.836 108.851 145.616 1.00 57.18  ? 102 THR H C   1 
ATOM   9587  O O   . THR D 4 102 ? 108.449 108.012 144.821 1.00 82.45  ? 102 THR H O   1 
ATOM   9588  C CB  . THR D 4 102 ? 109.923 107.005 146.930 1.00 203.20 ? 102 THR H CB  1 
ATOM   9589  O OG1 . THR D 4 102 ? 110.467 106.744 148.227 1.00 203.77 ? 102 THR H OG1 1 
ATOM   9590  C CG2 . THR D 4 102 ? 111.026 106.865 145.906 1.00 271.01 ? 102 THR H CG2 1 
ATOM   9591  N N   . TYR D 4 103 ? 108.879 110.177 145.400 1.00 54.67  ? 103 TYR H N   1 
ATOM   9592  C CA  . TYR D 4 103 ? 108.451 110.934 144.177 1.00 81.56  ? 103 TYR H CA  1 
ATOM   9593  C C   . TYR D 4 103 ? 106.987 111.469 144.055 1.00 66.27  ? 103 TYR H C   1 
ATOM   9594  O O   . TYR D 4 103 ? 106.759 112.424 143.263 1.00 40.24  ? 103 TYR H O   1 
ATOM   9595  C CB  . TYR D 4 103 ? 108.656 110.406 142.740 1.00 53.17  ? 103 TYR H CB  1 
ATOM   9596  C CG  . TYR D 4 103 ? 107.663 109.597 141.968 1.00 43.88  ? 103 TYR H CG  1 
ATOM   9597  C CD1 . TYR D 4 103 ? 106.706 110.235 141.290 1.00 60.25  ? 103 TYR H CD1 1 
ATOM   9598  C CD2 . TYR D 4 103 ? 107.696 108.172 141.871 1.00 77.52  ? 103 TYR H CD2 1 
ATOM   9599  C CE1 . TYR D 4 103 ? 105.778 109.450 140.562 1.00 161.05 ? 103 TYR H CE1 1 
ATOM   9600  C CE2 . TYR D 4 103 ? 106.784 107.361 141.187 1.00 45.38  ? 103 TYR H CE2 1 
ATOM   9601  C CZ  . TYR D 4 103 ? 105.815 108.039 140.500 1.00 101.70 ? 103 TYR H CZ  1 
ATOM   9602  O OH  . TYR D 4 103 ? 104.863 107.385 139.772 1.00 86.85  ? 103 TYR H OH  1 
ATOM   9603  N N   . TYR D 4 104 ? 106.013 110.935 144.820 1.00 47.54  ? 104 TYR H N   1 
ATOM   9604  C CA  . TYR D 4 104 ? 104.689 111.495 144.702 1.00 56.00  ? 104 TYR H CA  1 
ATOM   9605  C C   . TYR D 4 104 ? 104.595 112.947 145.197 1.00 60.82  ? 104 TYR H C   1 
ATOM   9606  O O   . TYR D 4 104 ? 105.116 113.289 146.240 1.00 66.37  ? 104 TYR H O   1 
ATOM   9607  C CB  . TYR D 4 104 ? 103.733 110.605 145.461 1.00 77.75  ? 104 TYR H CB  1 
ATOM   9608  C CG  . TYR D 4 104 ? 103.510 109.196 144.944 1.00 62.81  ? 104 TYR H CG  1 
ATOM   9609  C CD1 . TYR D 4 104 ? 104.005 108.760 143.759 1.00 81.58  ? 104 TYR H CD1 1 
ATOM   9610  C CD2 . TYR D 4 104 ? 102.796 108.299 145.689 1.00 90.51  ? 104 TYR H CD2 1 
ATOM   9611  C CE1 . TYR D 4 104 ? 103.790 107.484 143.297 1.00 96.51  ? 104 TYR H CE1 1 
ATOM   9612  C CE2 . TYR D 4 104 ? 102.586 107.012 145.253 1.00 152.49 ? 104 TYR H CE2 1 
ATOM   9613  C CZ  . TYR D 4 104 ? 103.083 106.595 144.035 1.00 114.53 ? 104 TYR H CZ  1 
ATOM   9614  O OH  . TYR D 4 104 ? 102.931 105.336 143.518 1.00 188.21 ? 104 TYR H OH  1 
ATOM   9615  N N   . PRO D 4 105 ? 103.910 113.836 144.456 1.00 48.28  ? 105 PRO H N   1 
ATOM   9616  C CA  . PRO D 4 105 ? 103.920 115.257 144.738 1.00 55.03  ? 105 PRO H CA  1 
ATOM   9617  C C   . PRO D 4 105 ? 102.970 115.791 145.799 1.00 50.85  ? 105 PRO H C   1 
ATOM   9618  O O   . PRO D 4 105 ? 101.983 116.424 145.512 1.00 57.11  ? 105 PRO H O   1 
ATOM   9619  C CB  . PRO D 4 105 ? 103.532 115.844 143.361 1.00 67.72  ? 105 PRO H CB  1 
ATOM   9620  C CG  . PRO D 4 105 ? 102.613 114.842 142.689 1.00 54.61  ? 105 PRO H CG  1 
ATOM   9621  C CD  . PRO D 4 105 ? 103.091 113.535 143.286 1.00 53.50  ? 105 PRO H CD  1 
ATOM   9622  N N   . TRP D 4 106 ? 103.302 115.573 147.040 1.00 55.65  ? 106 TRP H N   1 
ATOM   9623  C CA  . TRP D 4 106 ? 102.830 116.490 148.064 1.00 75.06  ? 106 TRP H CA  1 
ATOM   9624  C C   . TRP D 4 106 ? 103.936 116.710 149.045 1.00 73.82  ? 106 TRP H C   1 
ATOM   9625  O O   . TRP D 4 106 ? 104.674 115.780 149.349 1.00 110.28 ? 106 TRP H O   1 
ATOM   9626  C CB  . TRP D 4 106 ? 101.599 115.993 148.836 1.00 69.34  ? 106 TRP H CB  1 
ATOM   9627  C CG  . TRP D 4 106 ? 101.703 114.794 149.728 1.00 75.58  ? 106 TRP H CG  1 
ATOM   9628  C CD1 . TRP D 4 106 ? 102.029 114.769 151.049 1.00 85.11  ? 106 TRP H CD1 1 
ATOM   9629  C CD2 . TRP D 4 106 ? 101.475 113.429 149.338 1.00 81.59  ? 106 TRP H CD2 1 
ATOM   9630  N NE1 . TRP D 4 106 ? 102.003 113.483 151.526 1.00 111.19 ? 106 TRP H NE1 1 
ATOM   9631  C CE2 . TRP D 4 106 ? 101.676 112.662 150.483 1.00 94.22  ? 106 TRP H CE2 1 
ATOM   9632  C CE3 . TRP D 4 106 ? 101.144 112.836 148.138 1.00 94.78  ? 106 TRP H CE3 1 
ATOM   9633  C CZ2 . TRP D 4 106 ? 101.537 111.307 150.453 1.00 86.54  ? 106 TRP H CZ2 1 
ATOM   9634  C CZ3 . TRP D 4 106 ? 101.028 111.494 148.101 1.00 143.45 ? 106 TRP H CZ3 1 
ATOM   9635  C CH2 . TRP D 4 106 ? 101.219 110.752 149.254 1.00 113.59 ? 106 TRP H CH2 1 
ATOM   9636  N N   . PHE D 4 107 ? 104.020 117.935 149.517 1.00 65.89  ? 107 PHE H N   1 
ATOM   9637  C CA  . PHE D 4 107 ? 105.302 118.430 149.919 1.00 60.28  ? 107 PHE H CA  1 
ATOM   9638  C C   . PHE D 4 107 ? 105.303 118.782 151.382 1.00 64.64  ? 107 PHE H C   1 
ATOM   9639  O O   . PHE D 4 107 ? 105.031 119.913 151.708 1.00 83.17  ? 107 PHE H O   1 
ATOM   9640  C CB  . PHE D 4 107 ? 105.656 119.642 149.052 1.00 62.26  ? 107 PHE H CB  1 
ATOM   9641  C CG  . PHE D 4 107 ? 105.554 119.391 147.589 1.00 50.50  ? 107 PHE H CG  1 
ATOM   9642  C CD1 . PHE D 4 107 ? 106.139 118.318 147.066 1.00 50.53  ? 107 PHE H CD1 1 
ATOM   9643  C CD2 . PHE D 4 107 ? 104.850 120.172 146.771 1.00 69.05  ? 107 PHE H CD2 1 
ATOM   9644  C CE1 . PHE D 4 107 ? 106.029 118.019 145.737 1.00 58.33  ? 107 PHE H CE1 1 
ATOM   9645  C CE2 . PHE D 4 107 ? 104.709 119.841 145.441 1.00 85.79  ? 107 PHE H CE2 1 
ATOM   9646  C CZ  . PHE D 4 107 ? 105.334 118.792 144.919 1.00 59.68  ? 107 PHE H CZ  1 
ATOM   9647  N N   . PRO D 4 108 ? 105.635 117.862 152.294 1.00 62.45  ? 108 PRO H N   1 
ATOM   9648  C CA  . PRO D 4 108 ? 105.721 118.231 153.676 1.00 66.75  ? 108 PRO H CA  1 
ATOM   9649  C C   . PRO D 4 108 ? 106.933 119.091 153.948 1.00 72.29  ? 108 PRO H C   1 
ATOM   9650  O O   . PRO D 4 108 ? 106.761 119.969 154.824 1.00 123.84 ? 108 PRO H O   1 
ATOM   9651  C CB  . PRO D 4 108 ? 105.844 116.905 154.349 1.00 79.05  ? 108 PRO H CB  1 
ATOM   9652  C CG  . PRO D 4 108 ? 106.565 116.102 153.361 1.00 91.12  ? 108 PRO H CG  1 
ATOM   9653  C CD  . PRO D 4 108 ? 105.950 116.472 152.059 1.00 54.10  ? 108 PRO H CD  1 
ATOM   9654  N N   . TYR D 4 109 ? 108.083 118.885 153.270 1.00 52.93  ? 109 TYR H N   1 
ATOM   9655  C CA  . TYR D 4 109 ? 109.272 119.611 153.686 1.00 91.61  ? 109 TYR H CA  1 
ATOM   9656  C C   . TYR D 4 109 ? 109.740 120.576 152.605 1.00 86.28  ? 109 TYR H C   1 
ATOM   9657  O O   . TYR D 4 109 ? 110.065 120.137 151.530 1.00 106.24 ? 109 TYR H O   1 
ATOM   9658  C CB  . TYR D 4 109 ? 110.380 118.628 154.048 1.00 100.34 ? 109 TYR H CB  1 
ATOM   9659  C CG  . TYR D 4 109 ? 109.970 117.549 155.025 1.00 80.46  ? 109 TYR H CG  1 
ATOM   9660  C CD1 . TYR D 4 109 ? 109.494 117.831 156.286 1.00 119.13 ? 109 TYR H CD1 1 
ATOM   9661  C CD2 . TYR D 4 109 ? 110.074 116.236 154.662 1.00 96.79  ? 109 TYR H CD2 1 
ATOM   9662  C CE1 . TYR D 4 109 ? 109.124 116.807 157.162 1.00 189.24 ? 109 TYR H CE1 1 
ATOM   9663  C CE2 . TYR D 4 109 ? 109.709 115.209 155.518 1.00 151.56 ? 109 TYR H CE2 1 
ATOM   9664  C CZ  . TYR D 4 109 ? 109.227 115.474 156.777 1.00 171.03 ? 109 TYR H CZ  1 
ATOM   9665  O OH  . TYR D 4 109 ? 108.913 114.340 157.487 1.00 151.60 ? 109 TYR H OH  1 
ATOM   9666  N N   . TRP D 4 110 ? 109.799 121.858 152.916 1.00 73.97  ? 110 TRP H N   1 
ATOM   9667  C CA  . TRP D 4 110 ? 110.276 122.864 151.989 1.00 71.48  ? 110 TRP H CA  1 
ATOM   9668  C C   . TRP D 4 110 ? 111.523 123.571 152.541 1.00 77.36  ? 110 TRP H C   1 
ATOM   9669  O O   . TRP D 4 110 ? 111.653 123.852 153.725 1.00 92.03  ? 110 TRP H O   1 
ATOM   9670  C CB  . TRP D 4 110 ? 109.182 123.931 151.814 1.00 74.21  ? 110 TRP H CB  1 
ATOM   9671  C CG  . TRP D 4 110 ? 107.873 123.508 151.236 1.00 52.16  ? 110 TRP H CG  1 
ATOM   9672  C CD1 . TRP D 4 110 ? 107.077 122.586 151.784 1.00 53.50  ? 110 TRP H CD1 1 
ATOM   9673  C CD2 . TRP D 4 110 ? 107.214 123.902 150.018 1.00 45.73  ? 110 TRP H CD2 1 
ATOM   9674  N NE1 . TRP D 4 110 ? 105.966 122.418 151.021 1.00 57.26  ? 110 TRP H NE1 1 
ATOM   9675  C CE2 . TRP D 4 110 ? 106.034 123.189 149.923 1.00 46.37  ? 110 TRP H CE2 1 
ATOM   9676  C CE3 . TRP D 4 110 ? 107.493 124.768 148.980 1.00 65.07  ? 110 TRP H CE3 1 
ATOM   9677  C CZ2 . TRP D 4 110 ? 105.154 123.293 148.873 1.00 69.24  ? 110 TRP H CZ2 1 
ATOM   9678  C CZ3 . TRP D 4 110 ? 106.653 124.869 147.899 1.00 66.92  ? 110 TRP H CZ3 1 
ATOM   9679  C CH2 . TRP D 4 110 ? 105.502 124.117 147.839 1.00 80.98  ? 110 TRP H CH2 1 
ATOM   9680  N N   . GLY D 4 111 ? 112.459 123.898 151.669 1.00 107.88 ? 111 GLY H N   1 
ATOM   9681  C CA  . GLY D 4 111 ? 113.501 124.837 152.038 1.00 154.03 ? 111 GLY H CA  1 
ATOM   9682  C C   . GLY D 4 111 ? 112.938 126.271 152.068 1.00 93.99  ? 111 GLY H C   1 
ATOM   9683  O O   . GLY D 4 111 ? 112.072 126.578 151.301 1.00 103.22 ? 111 GLY H O   1 
ATOM   9684  N N   . GLN D 4 112 ? 113.483 127.156 152.913 1.00 128.21 ? 112 GLN H N   1 
ATOM   9685  C CA  . GLN D 4 112 ? 113.240 128.603 152.883 1.00 109.87 ? 112 GLN H CA  1 
ATOM   9686  C C   . GLN D 4 112 ? 113.674 129.127 151.518 1.00 86.44  ? 112 GLN H C   1 
ATOM   9687  O O   . GLN D 4 112 ? 114.714 128.701 151.033 1.00 145.13 ? 112 GLN H O   1 
ATOM   9688  C CB  . GLN D 4 112 ? 114.005 129.310 153.991 1.00 146.09 ? 112 GLN H CB  1 
ATOM   9689  C CG  . GLN D 4 112 ? 113.888 128.657 155.376 1.00 273.76 ? 112 GLN H CG  1 
ATOM   9690  C CD  . GLN D 4 112 ? 112.516 128.623 156.026 1.00 355.92 ? 112 GLN H CD  1 
ATOM   9691  O OE1 . GLN D 4 112 ? 111.506 128.257 155.431 1.00 309.86 ? 112 GLN H OE1 1 
ATOM   9692  N NE2 . GLN D 4 112 ? 112.459 129.001 157.295 1.00 447.44 ? 112 GLN H NE2 1 
ATOM   9693  N N   . GLY D 4 113 ? 112.876 129.972 150.868 1.00 81.44  ? 113 GLY H N   1 
ATOM   9694  C CA  . GLY D 4 113 ? 113.008 130.175 149.416 1.00 120.87 ? 113 GLY H CA  1 
ATOM   9695  C C   . GLY D 4 113 ? 114.243 130.988 148.967 1.00 95.56  ? 113 GLY H C   1 
ATOM   9696  O O   . GLY D 4 113 ? 114.702 131.851 149.709 1.00 116.04 ? 113 GLY H O   1 
ATOM   9697  N N   . THR D 4 114 ? 114.750 130.738 147.753 1.00 75.64  ? 114 THR H N   1 
ATOM   9698  C CA  . THR D 4 114 ? 115.795 131.557 147.137 1.00 78.32  ? 114 THR H CA  1 
ATOM   9699  C C   . THR D 4 114 ? 115.169 132.648 146.280 1.00 81.14  ? 114 THR H C   1 
ATOM   9700  O O   . THR D 4 114 ? 114.464 132.334 145.340 1.00 93.37  ? 114 THR H O   1 
ATOM   9701  C CB  . THR D 4 114 ? 116.714 130.713 146.244 1.00 115.86 ? 114 THR H CB  1 
ATOM   9702  O OG1 . THR D 4 114 ? 117.287 129.634 147.000 1.00 122.29 ? 114 THR H OG1 1 
ATOM   9703  C CG2 . THR D 4 114 ? 117.800 131.555 145.611 1.00 159.26 ? 114 THR H CG2 1 
ATOM   9704  N N   . LEU D 4 115 ? 115.377 133.914 146.613 1.00 111.53 ? 115 LEU H N   1 
ATOM   9705  C CA  . LEU D 4 115 ? 114.702 134.999 145.910 1.00 112.96 ? 115 LEU H CA  1 
ATOM   9706  C C   . LEU D 4 115 ? 115.562 135.423 144.731 1.00 109.20 ? 115 LEU H C   1 
ATOM   9707  O O   . LEU D 4 115 ? 116.624 136.004 144.905 1.00 135.52 ? 115 LEU H O   1 
ATOM   9708  C CB  . LEU D 4 115 ? 114.455 136.177 146.854 1.00 116.94 ? 115 LEU H CB  1 
ATOM   9709  C CG  . LEU D 4 115 ? 113.377 137.146 146.411 1.00 118.89 ? 115 LEU H CG  1 
ATOM   9710  C CD1 . LEU D 4 115 ? 113.142 138.165 147.536 1.00 175.91 ? 115 LEU H CD1 1 
ATOM   9711  C CD2 . LEU D 4 115 ? 113.734 137.840 145.100 1.00 140.10 ? 115 LEU H CD2 1 
ATOM   9712  N N   . VAL D 4 116 ? 115.082 135.130 143.529 1.00 97.33  ? 116 VAL H N   1 
ATOM   9713  C CA  . VAL D 4 116 ? 115.781 135.396 142.277 1.00 91.57  ? 116 VAL H CA  1 
ATOM   9714  C C   . VAL D 4 116 ? 115.214 136.643 141.619 1.00 115.75 ? 116 VAL H C   1 
ATOM   9715  O O   . VAL D 4 116 ? 114.065 136.647 141.149 1.00 122.60 ? 116 VAL H O   1 
ATOM   9716  C CB  . VAL D 4 116 ? 115.602 134.178 141.369 1.00 108.81 ? 116 VAL H CB  1 
ATOM   9717  C CG1 . VAL D 4 116 ? 115.945 134.396 139.908 1.00 104.01 ? 116 VAL H CG1 1 
ATOM   9718  C CG2 . VAL D 4 116 ? 116.372 133.029 141.963 1.00 119.41 ? 116 VAL H CG2 1 
ATOM   9719  N N   . THR D 4 117 ? 116.045 137.695 141.571 1.00 120.98 ? 117 THR H N   1 
ATOM   9720  C CA  . THR D 4 117 ? 115.660 138.943 140.936 1.00 140.95 ? 117 THR H CA  1 
ATOM   9721  C C   . THR D 4 117 ? 116.364 139.087 139.588 1.00 134.26 ? 117 THR H C   1 
ATOM   9722  O O   . THR D 4 117 ? 117.578 138.931 139.537 1.00 111.80 ? 117 THR H O   1 
ATOM   9723  C CB  . THR D 4 117 ? 116.006 140.152 141.819 1.00 143.73 ? 117 THR H CB  1 
ATOM   9724  O OG1 . THR D 4 117 ? 115.737 139.905 143.202 1.00 145.96 ? 117 THR H OG1 1 
ATOM   9725  C CG2 . THR D 4 117 ? 115.236 141.363 141.348 1.00 162.32 ? 117 THR H CG2 1 
ATOM   9726  N N   . VAL D 4 118 ? 115.617 139.414 138.525 1.00 112.35 ? 118 VAL H N   1 
ATOM   9727  C CA  . VAL D 4 118 ? 116.196 139.534 137.197 1.00 129.18 ? 118 VAL H CA  1 
ATOM   9728  C C   . VAL D 4 118 ? 116.184 141.015 136.811 1.00 180.29 ? 118 VAL H C   1 
ATOM   9729  O O   . VAL D 4 118 ? 115.122 141.563 136.512 1.00 159.09 ? 118 VAL H O   1 
ATOM   9730  C CB  . VAL D 4 118 ? 115.469 138.667 136.160 1.00 113.61 ? 118 VAL H CB  1 
ATOM   9731  C CG1 . VAL D 4 118 ? 116.052 138.826 134.766 1.00 166.23 ? 118 VAL H CG1 1 
ATOM   9732  C CG2 . VAL D 4 118 ? 115.528 137.212 136.518 1.00 150.84 ? 118 VAL H CG2 1 
ATOM   9733  N N   . SER D 4 119 ? 117.379 141.639 136.816 1.00 178.06 ? 119 SER H N   1 
ATOM   9734  C CA  . SER D 4 119 ? 117.526 143.069 136.604 1.00 194.79 ? 119 SER H CA  1 
ATOM   9735  C C   . SER D 4 119 ? 118.950 143.397 136.182 1.00 202.60 ? 119 SER H C   1 
ATOM   9736  O O   . SER D 4 119 ? 119.889 142.750 136.628 1.00 199.81 ? 119 SER H O   1 
ATOM   9737  C CB  . SER D 4 119 ? 117.156 143.844 137.837 1.00 195.98 ? 119 SER H CB  1 
ATOM   9738  O OG  . SER D 4 119 ? 117.313 145.243 137.616 1.00 230.38 ? 119 SER H OG  1 
ATOM   9739  N N   . ALA D 4 120 ? 119.081 144.415 135.323 1.00 235.04 ? 120 ALA H N   1 
ATOM   9740  C CA  . ALA D 4 120 ? 120.377 144.896 134.874 1.00 267.03 ? 120 ALA H CA  1 
ATOM   9741  C C   . ALA D 4 120 ? 121.038 145.806 135.917 1.00 253.02 ? 120 ALA H C   1 
ATOM   9742  O O   . ALA D 4 120 ? 122.264 145.952 135.882 1.00 251.40 ? 120 ALA H O   1 
ATOM   9743  C CB  . ALA D 4 120 ? 120.204 145.601 133.551 1.00 293.11 ? 120 ALA H CB  1 
ATOM   9744  N N   . ALA D 4 121 ? 120.239 146.413 136.820 1.00 232.39 ? 121 ALA H N   1 
ATOM   9745  C CA  . ALA D 4 121 ? 120.734 147.283 137.877 1.00 216.33 ? 121 ALA H CA  1 
ATOM   9746  C C   . ALA D 4 121 ? 121.658 146.504 138.811 1.00 164.00 ? 121 ALA H C   1 
ATOM   9747  O O   . ALA D 4 121 ? 121.398 145.364 139.165 1.00 146.83 ? 121 ALA H O   1 
ATOM   9748  C CB  . ALA D 4 121 ? 119.582 147.923 138.639 1.00 212.20 ? 121 ALA H CB  1 
ATOM   9749  N N   . LYS D 4 122 ? 122.735 147.175 139.229 1.00 209.67 ? 122 LYS H N   1 
ATOM   9750  C CA  . LYS D 4 122 ? 123.833 146.547 139.936 1.00 208.71 ? 122 LYS H CA  1 
ATOM   9751  C C   . LYS D 4 122 ? 123.483 146.384 141.422 1.00 178.24 ? 122 LYS H C   1 
ATOM   9752  O O   . LYS D 4 122 ? 122.689 147.145 142.020 1.00 127.02 ? 122 LYS H O   1 
ATOM   9753  C CB  . LYS D 4 122 ? 125.118 147.368 139.749 1.00 280.00 ? 122 LYS H CB  1 
ATOM   9754  C CG  . LYS D 4 122 ? 125.103 148.811 140.258 1.00 320.31 ? 122 LYS H CG  1 
ATOM   9755  C CD  . LYS D 4 122 ? 126.434 149.500 140.098 1.00 327.38 ? 122 LYS H CD  1 
ATOM   9756  C CE  . LYS D 4 122 ? 126.412 150.932 140.587 1.00 365.10 ? 122 LYS H CE  1 
ATOM   9757  N NZ  . LYS D 4 122 ? 127.744 151.570 140.465 1.00 398.28 ? 122 LYS H NZ  1 
ATOM   9758  N N   . THR D 4 123 ? 124.119 145.357 142.011 1.00 162.02 ? 123 THR H N   1 
ATOM   9759  C CA  . THR D 4 123 ? 124.208 145.173 143.452 1.00 184.44 ? 123 THR H CA  1 
ATOM   9760  C C   . THR D 4 123 ? 124.645 146.473 144.120 1.00 168.81 ? 123 THR H C   1 
ATOM   9761  O O   . THR D 4 123 ? 125.583 147.115 143.651 1.00 180.95 ? 123 THR H O   1 
ATOM   9762  C CB  . THR D 4 123 ? 125.196 144.055 143.811 1.00 225.84 ? 123 THR H CB  1 
ATOM   9763  O OG1 . THR D 4 123 ? 124.793 142.853 143.149 1.00 244.50 ? 123 THR H OG1 1 
ATOM   9764  C CG2 . THR D 4 123 ? 125.279 143.802 145.298 1.00 213.80 ? 123 THR H CG2 1 
ATOM   9765  N N   . THR D 4 124 ? 123.949 146.846 145.202 1.00 176.70 ? 124 THR H N   1 
ATOM   9766  C CA  . THR D 4 124 ? 124.177 148.119 145.867 1.00 192.96 ? 124 THR H CA  1 
ATOM   9767  C C   . THR D 4 124 ? 124.010 147.911 147.373 1.00 193.37 ? 124 THR H C   1 
ATOM   9768  O O   . THR D 4 124 ? 122.885 147.757 147.858 1.00 231.87 ? 124 THR H O   1 
ATOM   9769  C CB  . THR D 4 124 ? 123.239 149.203 145.320 1.00 239.36 ? 124 THR H CB  1 
ATOM   9770  O OG1 . THR D 4 124 ? 123.364 149.342 143.894 1.00 189.05 ? 124 THR H OG1 1 
ATOM   9771  C CG2 . THR D 4 124 ? 123.521 150.547 145.979 1.00 235.70 ? 124 THR H CG2 1 
ATOM   9772  N N   . PRO D 4 125 ? 125.108 147.874 148.164 1.00 212.08 ? 125 PRO H N   1 
ATOM   9773  C CA  . PRO D 4 125 ? 124.987 147.710 149.611 1.00 213.70 ? 125 PRO H CA  1 
ATOM   9774  C C   . PRO D 4 125 ? 124.170 148.809 150.288 1.00 233.61 ? 125 PRO H C   1 
ATOM   9775  O O   . PRO D 4 125 ? 124.144 149.949 149.823 1.00 223.53 ? 125 PRO H O   1 
ATOM   9776  C CB  . PRO D 4 125 ? 126.433 147.737 150.110 1.00 250.07 ? 125 PRO H CB  1 
ATOM   9777  C CG  . PRO D 4 125 ? 127.236 147.323 148.903 1.00 334.14 ? 125 PRO H CG  1 
ATOM   9778  C CD  . PRO D 4 125 ? 126.510 147.948 147.728 1.00 284.40 ? 125 PRO H CD  1 
ATOM   9779  N N   . PRO D 4 126 ? 123.478 148.478 151.405 1.00 231.29 ? 126 PRO H N   1 
ATOM   9780  C CA  . PRO D 4 126 ? 122.554 149.404 152.063 1.00 182.83 ? 126 PRO H CA  1 
ATOM   9781  C C   . PRO D 4 126 ? 123.252 150.499 152.866 1.00 210.84 ? 126 PRO H C   1 
ATOM   9782  O O   . PRO D 4 126 ? 124.358 150.308 153.373 1.00 222.41 ? 126 PRO H O   1 
ATOM   9783  C CB  . PRO D 4 126 ? 121.756 148.504 153.010 1.00 187.21 ? 126 PRO H CB  1 
ATOM   9784  C CG  . PRO D 4 126 ? 122.708 147.367 153.339 1.00 228.13 ? 126 PRO H CG  1 
ATOM   9785  C CD  . PRO D 4 126 ? 123.555 147.185 152.101 1.00 220.50 ? 126 PRO H CD  1 
ATOM   9786  N N   . SER D 4 127 ? 122.576 151.652 152.959 1.00 223.66 ? 127 SER H N   1 
ATOM   9787  C CA  . SER D 4 127 ? 122.949 152.736 153.855 1.00 226.66 ? 127 SER H CA  1 
ATOM   9788  C C   . SER D 4 127 ? 121.920 152.820 154.980 1.00 196.86 ? 127 SER H C   1 
ATOM   9789  O O   . SER D 4 127 ? 120.730 152.966 154.694 1.00 224.92 ? 127 SER H O   1 
ATOM   9790  C CB  . SER D 4 127 ? 123.036 154.024 153.092 1.00 268.95 ? 127 SER H CB  1 
ATOM   9791  O OG  . SER D 4 127 ? 124.100 154.005 152.146 1.00 316.63 ? 127 SER H OG  1 
ATOM   9792  N N   . ASP D 4 128 ? 122.379 152.725 156.242 1.00 203.23 ? 128 ASP H N   1 
ATOM   9793  C CA  . ASP D 4 128 ? 121.510 152.585 157.415 1.00 199.68 ? 128 ASP H CA  1 
ATOM   9794  C C   . ASP D 4 128 ? 121.565 153.862 158.245 1.00 210.19 ? 128 ASP H C   1 
ATOM   9795  O O   . ASP D 4 128 ? 122.641 154.402 158.502 1.00 256.40 ? 128 ASP H O   1 
ATOM   9796  C CB  . ASP D 4 128 ? 121.888 151.407 158.314 1.00 180.86 ? 128 ASP H CB  1 
ATOM   9797  C CG  . ASP D 4 128 ? 122.409 150.241 157.499 1.00 259.67 ? 128 ASP H CG  1 
ATOM   9798  O OD1 . ASP D 4 128 ? 121.674 149.799 156.606 1.00 300.55 ? 128 ASP H OD1 1 
ATOM   9799  O OD2 . ASP D 4 128 ? 123.542 149.807 157.757 1.00 361.39 ? 128 ASP H OD2 1 
ATOM   9800  N N   . TYR D 4 129 ? 120.397 154.333 158.666 1.00 186.34 ? 129 TYR H N   1 
ATOM   9801  C CA  . TYR D 4 129 ? 120.280 155.631 159.307 1.00 180.24 ? 129 TYR H CA  1 
ATOM   9802  C C   . TYR D 4 129 ? 119.326 155.473 160.479 1.00 176.75 ? 129 TYR H C   1 
ATOM   9803  O O   . TYR D 4 129 ? 118.132 155.203 160.282 1.00 267.86 ? 129 TYR H O   1 
ATOM   9804  C CB  . TYR D 4 129 ? 119.834 156.650 158.254 1.00 205.18 ? 129 TYR H CB  1 
ATOM   9805  C CG  . TYR D 4 129 ? 120.871 156.945 157.180 1.00 233.32 ? 129 TYR H CG  1 
ATOM   9806  C CD1 . TYR D 4 129 ? 122.151 157.380 157.518 1.00 255.83 ? 129 TYR H CD1 1 
ATOM   9807  C CD2 . TYR D 4 129 ? 120.574 156.789 155.826 1.00 217.88 ? 129 TYR H CD2 1 
ATOM   9808  C CE1 . TYR D 4 129 ? 123.098 157.653 156.543 1.00 282.57 ? 129 TYR H CE1 1 
ATOM   9809  C CE2 . TYR D 4 129 ? 121.509 157.067 154.839 1.00 211.49 ? 129 TYR H CE2 1 
ATOM   9810  C CZ  . TYR D 4 129 ? 122.777 157.498 155.203 1.00 297.63 ? 129 TYR H CZ  1 
ATOM   9811  O OH  . TYR D 4 129 ? 123.728 157.776 154.259 1.00 384.02 ? 129 TYR H OH  1 
ATOM   9812  N N   . PRO D 4 130 ? 119.820 155.609 161.727 1.00 162.61 ? 130 PRO H N   1 
ATOM   9813  C CA  . PRO D 4 130 ? 118.984 155.395 162.906 1.00 194.90 ? 130 PRO H CA  1 
ATOM   9814  C C   . PRO D 4 130 ? 118.054 156.572 163.169 1.00 211.10 ? 130 PRO H C   1 
ATOM   9815  O O   . PRO D 4 130 ? 118.373 157.701 162.790 1.00 209.27 ? 130 PRO H O   1 
ATOM   9816  C CB  . PRO D 4 130 ? 120.007 155.217 164.034 1.00 213.25 ? 130 PRO H CB  1 
ATOM   9817  C CG  . PRO D 4 130 ? 121.188 156.056 163.587 1.00 244.94 ? 130 PRO H CG  1 
ATOM   9818  C CD  . PRO D 4 130 ? 121.201 155.954 162.076 1.00 199.72 ? 130 PRO H CD  1 
ATOM   9819  N N   . LEU D 4 131 ? 116.913 156.272 163.819 1.00 213.99 ? 131 LEU H N   1 
ATOM   9820  C CA  . LEU D 4 131 ? 115.860 157.238 164.089 1.00 213.78 ? 131 LEU H CA  1 
ATOM   9821  C C   . LEU D 4 131 ? 115.585 157.284 165.593 1.00 225.60 ? 131 LEU H C   1 
ATOM   9822  O O   . LEU D 4 131 ? 115.288 156.252 166.188 1.00 166.78 ? 131 LEU H O   1 
ATOM   9823  C CB  . LEU D 4 131 ? 114.609 156.827 163.308 1.00 197.10 ? 131 LEU H CB  1 
ATOM   9824  C CG  . LEU D 4 131 ? 114.741 156.709 161.786 1.00 180.47 ? 131 LEU H CG  1 
ATOM   9825  C CD1 . LEU D 4 131 ? 113.439 156.243 161.174 1.00 202.49 ? 131 LEU H CD1 1 
ATOM   9826  C CD2 . LEU D 4 131 ? 115.141 158.008 161.118 1.00 241.80 ? 131 LEU H CD2 1 
ATOM   9827  N N   . ALA D 4 132 ? 115.706 158.484 166.193 1.00 251.37 ? 132 ALA H N   1 
ATOM   9828  C CA  . ALA D 4 132 ? 115.427 158.687 167.610 1.00 284.67 ? 132 ALA H CA  1 
ATOM   9829  C C   . ALA D 4 132 ? 114.480 159.873 167.773 1.00 258.95 ? 132 ALA H C   1 
ATOM   9830  O O   . ALA D 4 132 ? 114.578 160.833 167.008 1.00 266.09 ? 132 ALA H O   1 
ATOM   9831  C CB  . ALA D 4 132 ? 116.704 158.886 168.395 1.00 331.27 ? 132 ALA H CB  1 
ATOM   9832  N N   . PRO D 4 133 ? 113.543 159.845 168.758 1.00 278.45 ? 133 PRO H N   1 
ATOM   9833  C CA  . PRO D 4 133 ? 112.392 160.763 168.761 1.00 321.69 ? 133 PRO H CA  1 
ATOM   9834  C C   . PRO D 4 133 ? 112.645 162.274 168.855 1.00 319.01 ? 133 PRO H C   1 
ATOM   9835  O O   . PRO D 4 133 ? 111.808 163.045 168.388 1.00 315.72 ? 133 PRO H O   1 
ATOM   9836  C CB  . PRO D 4 133 ? 111.601 160.333 170.016 1.00 390.83 ? 133 PRO H CB  1 
ATOM   9837  C CG  . PRO D 4 133 ? 112.045 158.909 170.275 1.00 384.93 ? 133 PRO H CG  1 
ATOM   9838  C CD  . PRO D 4 133 ? 113.511 158.924 169.914 1.00 298.43 ? 133 PRO H CD  1 
ATOM   9839  N N   . GLY D 4 134 ? 113.770 162.698 169.457 1.00 346.50 ? 134 GLY H N   1 
ATOM   9840  C CA  . GLY D 4 134 ? 114.109 164.109 169.588 1.00 375.25 ? 134 GLY H CA  1 
ATOM   9841  C C   . GLY D 4 134 ? 113.378 164.789 170.749 1.00 377.62 ? 134 GLY H C   1 
ATOM   9842  O O   . GLY D 4 134 ? 113.528 164.372 171.894 1.00 299.67 ? 134 GLY H O   1 
ATOM   9843  N N   . SER D 4 135 ? 112.593 165.845 170.443 1.00 424.00 ? 135 SER H N   1 
ATOM   9844  C CA  . SER D 4 135 ? 111.871 166.635 171.438 1.00 440.86 ? 135 SER H CA  1 
ATOM   9845  C C   . SER D 4 135 ? 110.783 165.810 172.138 1.00 514.44 ? 135 SER H C   1 
ATOM   9846  O O   . SER D 4 135 ? 110.102 165.014 171.493 1.00 573.03 ? 135 SER H O   1 
ATOM   9847  C CB  . SER D 4 135 ? 111.274 167.874 170.805 1.00 404.81 ? 135 SER H CB  1 
ATOM   9848  O OG  . SER D 4 135 ? 112.291 168.724 170.283 1.00 309.51 ? 135 SER H OG  1 
ATOM   9849  N N   . ALA D 4 136 ? 110.640 166.011 173.464 1.00 503.31 ? 136 ALA H N   1 
ATOM   9850  C CA  . ALA D 4 136 ? 109.592 165.437 174.312 1.00 485.34 ? 136 ALA H CA  1 
ATOM   9851  C C   . ALA D 4 136 ? 109.575 163.900 174.294 1.00 479.37 ? 136 ALA H C   1 
ATOM   9852  O O   . ALA D 4 136 ? 108.520 163.291 174.501 1.00 439.18 ? 136 ALA H O   1 
ATOM   9853  C CB  . ALA D 4 136 ? 108.244 166.023 173.928 1.00 474.58 ? 136 ALA H CB  1 
ATOM   9854  N N   . ALA D 4 137 ? 110.749 163.277 174.082 1.00 506.03 ? 137 ALA H N   1 
ATOM   9855  C CA  . ALA D 4 137 ? 110.873 161.836 173.895 1.00 528.78 ? 137 ALA H CA  1 
ATOM   9856  C C   . ALA D 4 137 ? 110.417 161.068 175.137 1.00 537.22 ? 137 ALA H C   1 
ATOM   9857  O O   . ALA D 4 137 ? 109.587 160.165 175.031 1.00 518.16 ? 137 ALA H O   1 
ATOM   9858  C CB  . ALA D 4 137 ? 112.305 161.487 173.557 1.00 536.94 ? 137 ALA H CB  1 
ATOM   9859  N N   . GLN D 4 138 ? 110.960 161.451 176.307 1.00 548.27 ? 138 GLN H N   1 
ATOM   9860  C CA  . GLN D 4 138 ? 110.750 160.742 177.567 1.00 550.93 ? 138 GLN H CA  1 
ATOM   9861  C C   . GLN D 4 138 ? 109.462 161.177 178.284 1.00 534.84 ? 138 GLN H C   1 
ATOM   9862  O O   . GLN D 4 138 ? 109.209 160.704 179.392 1.00 512.15 ? 138 GLN H O   1 
ATOM   9863  C CB  . GLN D 4 138 ? 111.970 160.945 178.477 1.00 569.96 ? 138 GLN H CB  1 
ATOM   9864  C CG  . GLN D 4 138 ? 113.259 160.327 177.943 1.00 590.35 ? 138 GLN H CG  1 
ATOM   9865  C CD  . GLN D 4 138 ? 113.268 158.819 178.033 1.00 607.42 ? 138 GLN H CD  1 
ATOM   9866  O OE1 . GLN D 4 138 ? 112.893 158.124 177.090 1.00 636.22 ? 138 GLN H OE1 1 
ATOM   9867  N NE2 . GLN D 4 138 ? 113.689 158.298 179.175 1.00 602.49 ? 138 GLN H NE2 1 
ATOM   9868  N N   . THR D 4 139 ? 108.639 162.052 177.670 1.00 544.16 ? 139 THR H N   1 
ATOM   9869  C CA  . THR D 4 139 ? 107.359 162.485 178.228 1.00 545.19 ? 139 THR H CA  1 
ATOM   9870  C C   . THR D 4 139 ? 106.308 161.357 178.234 1.00 533.86 ? 139 THR H C   1 
ATOM   9871  O O   . THR D 4 139 ? 105.274 161.512 178.886 1.00 523.71 ? 139 THR H O   1 
ATOM   9872  C CB  . THR D 4 139 ? 106.865 163.747 177.492 1.00 550.14 ? 139 THR H CB  1 
ATOM   9873  O OG1 . THR D 4 139 ? 107.918 164.714 177.465 1.00 545.83 ? 139 THR H OG1 1 
ATOM   9874  C CG2 . THR D 4 139 ? 105.650 164.393 178.126 1.00 546.03 ? 139 THR H CG2 1 
ATOM   9875  N N   . ASN D 4 140 ? 106.554 160.231 177.530 1.00 502.91 ? 140 ASN H N   1 
ATOM   9876  C CA  . ASN D 4 140 ? 105.652 159.081 177.501 1.00 443.30 ? 140 ASN H CA  1 
ATOM   9877  C C   . ASN D 4 140 ? 106.363 157.821 178.014 1.00 383.72 ? 140 ASN H C   1 
ATOM   9878  O O   . ASN D 4 140 ? 107.587 157.704 177.928 1.00 405.72 ? 140 ASN H O   1 
ATOM   9879  C CB  . ASN D 4 140 ? 105.088 158.868 176.090 1.00 425.83 ? 140 ASN H CB  1 
ATOM   9880  C CG  . ASN D 4 140 ? 104.290 160.027 175.520 1.00 423.21 ? 140 ASN H CG  1 
ATOM   9881  O OD1 . ASN D 4 140 ? 104.136 160.125 174.304 1.00 374.79 ? 140 ASN H OD1 1 
ATOM   9882  N ND2 . ASN D 4 140 ? 103.777 160.909 176.362 1.00 444.64 ? 140 ASN H ND2 1 
ATOM   9883  N N   . SER D 4 141 ? 105.571 156.870 178.539 1.00 315.02 ? 141 SER H N   1 
ATOM   9884  C CA  . SER D 4 141 ? 106.079 155.711 179.268 1.00 344.25 ? 141 SER H CA  1 
ATOM   9885  C C   . SER D 4 141 ? 106.772 154.696 178.352 1.00 338.57 ? 141 SER H C   1 
ATOM   9886  O O   . SER D 4 141 ? 107.731 154.056 178.789 1.00 354.03 ? 141 SER H O   1 
ATOM   9887  C CB  . SER D 4 141 ? 104.967 155.053 180.056 1.00 350.80 ? 141 SER H CB  1 
ATOM   9888  O OG  . SER D 4 141 ? 103.903 154.653 179.206 1.00 337.77 ? 141 SER H OG  1 
ATOM   9889  N N   . MET D 4 142 ? 106.274 154.551 177.106 1.00 292.68 ? 142 MET H N   1 
ATOM   9890  C CA  . MET D 4 142 ? 106.874 153.716 176.070 1.00 273.23 ? 142 MET H CA  1 
ATOM   9891  C C   . MET D 4 142 ? 107.397 154.600 174.935 1.00 295.07 ? 142 MET H C   1 
ATOM   9892  O O   . MET D 4 142 ? 106.718 155.550 174.544 1.00 289.21 ? 142 MET H O   1 
ATOM   9893  C CB  . MET D 4 142 ? 105.833 152.741 175.511 1.00 254.01 ? 142 MET H CB  1 
ATOM   9894  C CG  . MET D 4 142 ? 105.474 151.619 176.465 1.00 284.40 ? 142 MET H CG  1 
ATOM   9895  S SD  . MET D 4 142 ? 106.790 150.394 176.671 1.00 296.76 ? 142 MET H SD  1 
ATOM   9896  C CE  . MET D 4 142 ? 105.877 148.977 177.277 1.00 352.16 ? 142 MET H CE  1 
ATOM   9897  N N   . VAL D 4 143 ? 108.597 154.277 174.411 1.00 303.31 ? 143 VAL H N   1 
ATOM   9898  C CA  . VAL D 4 143 ? 109.269 155.088 173.396 1.00 276.93 ? 143 VAL H CA  1 
ATOM   9899  C C   . VAL D 4 143 ? 109.641 154.219 172.198 1.00 246.92 ? 143 VAL H C   1 
ATOM   9900  O O   . VAL D 4 143 ? 110.158 153.107 172.361 1.00 217.09 ? 143 VAL H O   1 
ATOM   9901  C CB  . VAL D 4 143 ? 110.508 155.820 173.948 1.00 278.69 ? 143 VAL H CB  1 
ATOM   9902  C CG1 . VAL D 4 143 ? 110.095 156.873 174.965 1.00 332.26 ? 143 VAL H CG1 1 
ATOM   9903  C CG2 . VAL D 4 143 ? 111.566 154.887 174.536 1.00 234.32 ? 143 VAL H CG2 1 
ATOM   9904  N N   . THR D 4 144 ? 109.365 154.765 170.999 1.00 231.21 ? 144 THR H N   1 
ATOM   9905  C CA  . THR D 4 144 ? 109.605 154.070 169.744 1.00 264.99 ? 144 THR H CA  1 
ATOM   9906  C C   . THR D 4 144 ? 110.970 154.489 169.197 1.00 243.30 ? 144 THR H C   1 
ATOM   9907  O O   . THR D 4 144 ? 111.366 155.642 169.343 1.00 230.02 ? 144 THR H O   1 
ATOM   9908  C CB  . THR D 4 144 ? 108.478 154.327 168.733 1.00 283.76 ? 144 THR H CB  1 
ATOM   9909  O OG1 . THR D 4 144 ? 107.231 153.949 169.317 1.00 310.32 ? 144 THR H OG1 1 
ATOM   9910  C CG2 . THR D 4 144 ? 108.640 153.552 167.443 1.00 293.11 ? 144 THR H CG2 1 
ATOM   9911  N N   . LEU D 4 145 ? 111.659 153.526 168.566 1.00 236.63 ? 145 LEU H N   1 
ATOM   9912  C CA  . LEU D 4 145 ? 112.952 153.716 167.928 1.00 220.16 ? 145 LEU H CA  1 
ATOM   9913  C C   . LEU D 4 145 ? 112.911 153.098 166.532 1.00 223.75 ? 145 LEU H C   1 
ATOM   9914  O O   . LEU D 4 145 ? 112.129 152.188 166.265 1.00 206.68 ? 145 LEU H O   1 
ATOM   9915  C CB  . LEU D 4 145 ? 114.035 153.042 168.768 1.00 212.78 ? 145 LEU H CB  1 
ATOM   9916  C CG  . LEU D 4 145 ? 114.102 153.439 170.238 1.00 255.48 ? 145 LEU H CG  1 
ATOM   9917  C CD1 . LEU D 4 145 ? 115.064 152.520 170.975 1.00 294.97 ? 145 LEU H CD1 1 
ATOM   9918  C CD2 . LEU D 4 145 ? 114.521 154.896 170.402 1.00 268.21 ? 145 LEU H CD2 1 
ATOM   9919  N N   . GLY D 4 146 ? 113.761 153.598 165.634 1.00 205.88 ? 146 GLY H N   1 
ATOM   9920  C CA  . GLY D 4 146 ? 113.666 153.212 164.240 1.00 185.76 ? 146 GLY H CA  1 
ATOM   9921  C C   . GLY D 4 146 ? 115.002 153.169 163.520 1.00 157.02 ? 146 GLY H C   1 
ATOM   9922  O O   . GLY D 4 146 ? 116.029 153.632 164.023 1.00 201.39 ? 146 GLY H O   1 
ATOM   9923  N N   . CYS D 4 147 ? 114.938 152.606 162.317 1.00 158.37 ? 147 CYS H N   1 
ATOM   9924  C CA  . CYS D 4 147 ? 116.108 152.328 161.511 1.00 171.98 ? 147 CYS H CA  1 
ATOM   9925  C C   . CYS D 4 147 ? 115.667 152.408 160.062 1.00 160.13 ? 147 CYS H C   1 
ATOM   9926  O O   . CYS D 4 147 ? 115.035 151.474 159.578 1.00 236.61 ? 147 CYS H O   1 
ATOM   9927  C CB  . CYS D 4 147 ? 116.649 150.954 161.889 1.00 153.35 ? 147 CYS H CB  1 
ATOM   9928  S SG  . CYS D 4 147 ? 118.180 150.441 161.067 1.00 242.29 ? 147 CYS H SG  1 
ATOM   9929  N N   . LEU D 4 148 ? 115.972 153.533 159.406 1.00 130.26 ? 148 LEU H N   1 
ATOM   9930  C CA  . LEU D 4 148 ? 115.791 153.646 157.967 1.00 173.95 ? 148 LEU H CA  1 
ATOM   9931  C C   . LEU D 4 148 ? 116.942 152.906 157.256 1.00 156.93 ? 148 LEU H C   1 
ATOM   9932  O O   . LEU D 4 148 ? 118.096 153.020 157.653 1.00 172.73 ? 148 LEU H O   1 
ATOM   9933  C CB  . LEU D 4 148 ? 115.712 155.127 157.574 1.00 161.96 ? 148 LEU H CB  1 
ATOM   9934  C CG  . LEU D 4 148 ? 115.722 155.410 156.067 1.00 204.11 ? 148 LEU H CG  1 
ATOM   9935  C CD1 . LEU D 4 148 ? 114.408 155.006 155.403 1.00 263.57 ? 148 LEU H CD1 1 
ATOM   9936  C CD2 . LEU D 4 148 ? 116.012 156.874 155.798 1.00 253.74 ? 148 LEU H CD2 1 
ATOM   9937  N N   . VAL D 4 149 ? 116.597 152.153 156.202 1.00 139.42 ? 149 VAL H N   1 
ATOM   9938  C CA  . VAL D 4 149 ? 117.512 151.435 155.340 1.00 145.16 ? 149 VAL H CA  1 
ATOM   9939  C C   . VAL D 4 149 ? 117.252 151.938 153.924 1.00 158.07 ? 149 VAL H C   1 
ATOM   9940  O O   . VAL D 4 149 ? 116.152 151.760 153.395 1.00 191.82 ? 149 VAL H O   1 
ATOM   9941  C CB  . VAL D 4 149 ? 117.281 149.911 155.450 1.00 167.12 ? 149 VAL H CB  1 
ATOM   9942  C CG1 . VAL D 4 149 ? 118.179 149.107 154.500 1.00 165.32 ? 149 VAL H CG1 1 
ATOM   9943  C CG2 . VAL D 4 149 ? 117.402 149.429 156.900 1.00 132.39 ? 149 VAL H CG2 1 
ATOM   9944  N N   . LYS D 4 150 ? 118.253 152.556 153.290 1.00 183.00 ? 150 LYS H N   1 
ATOM   9945  C CA  . LYS D 4 150 ? 117.983 153.351 152.103 1.00 191.79 ? 150 LYS H CA  1 
ATOM   9946  C C   . LYS D 4 150 ? 118.887 152.925 150.935 1.00 194.11 ? 150 LYS H C   1 
ATOM   9947  O O   . LYS D 4 150 ? 120.025 152.512 151.114 1.00 132.28 ? 150 LYS H O   1 
ATOM   9948  C CB  . LYS D 4 150 ? 118.108 154.817 152.518 1.00 182.63 ? 150 LYS H CB  1 
ATOM   9949  C CG  . LYS D 4 150 ? 117.797 155.815 151.418 1.00 230.41 ? 150 LYS H CG  1 
ATOM   9950  C CD  . LYS D 4 150 ? 117.835 157.256 151.927 1.00 276.61 ? 150 LYS H CD  1 
ATOM   9951  C CE  . LYS D 4 150 ? 117.964 158.293 150.830 1.00 318.26 ? 150 LYS H CE  1 
ATOM   9952  N NZ  . LYS D 4 150 ? 116.872 158.182 149.832 1.00 332.72 ? 150 LYS H NZ  1 
ATOM   9953  N N   . GLY D 4 151 ? 118.337 153.037 149.720 1.00 219.30 ? 151 GLY H N   1 
ATOM   9954  C CA  . GLY D 4 151 ? 119.087 152.955 148.474 1.00 207.95 ? 151 GLY H CA  1 
ATOM   9955  C C   . GLY D 4 151 ? 119.792 151.629 148.209 1.00 182.70 ? 151 GLY H C   1 
ATOM   9956  O O   . GLY D 4 151 ? 120.747 151.606 147.427 1.00 228.67 ? 151 GLY H O   1 
ATOM   9957  N N   . TYR D 4 152 ? 119.326 150.537 148.832 1.00 161.21 ? 152 TYR H N   1 
ATOM   9958  C CA  . TYR D 4 152 ? 119.990 149.237 148.750 1.00 173.88 ? 152 TYR H CA  1 
ATOM   9959  C C   . TYR D 4 152 ? 119.444 148.403 147.577 1.00 160.03 ? 152 TYR H C   1 
ATOM   9960  O O   . TYR D 4 152 ? 118.441 148.762 146.979 1.00 138.38 ? 152 TYR H O   1 
ATOM   9961  C CB  . TYR D 4 152 ? 119.839 148.545 150.103 1.00 145.05 ? 152 TYR H CB  1 
ATOM   9962  C CG  . TYR D 4 152 ? 118.515 147.844 150.358 1.00 170.47 ? 152 TYR H CG  1 
ATOM   9963  C CD1 . TYR D 4 152 ? 117.412 148.530 150.866 1.00 181.90 ? 152 TYR H CD1 1 
ATOM   9964  C CD2 . TYR D 4 152 ? 118.368 146.489 150.070 1.00 159.30 ? 152 TYR H CD2 1 
ATOM   9965  C CE1 . TYR D 4 152 ? 116.211 147.886 151.084 1.00 163.66 ? 152 TYR H CE1 1 
ATOM   9966  C CE2 . TYR D 4 152 ? 117.172 145.840 150.280 1.00 157.30 ? 152 TYR H CE2 1 
ATOM   9967  C CZ  . TYR D 4 152 ? 116.094 146.541 150.791 1.00 149.61 ? 152 TYR H CZ  1 
ATOM   9968  O OH  . TYR D 4 152 ? 114.942 145.843 150.990 1.00 179.08 ? 152 TYR H OH  1 
ATOM   9969  N N   . PHE D 4 153 ? 120.125 147.289 147.240 1.00 128.21 ? 153 PHE H N   1 
ATOM   9970  C CA  . PHE D 4 153 ? 119.669 146.338 146.221 1.00 116.10 ? 153 PHE H CA  1 
ATOM   9971  C C   . PHE D 4 153 ? 120.461 145.045 146.306 1.00 119.24 ? 153 PHE H C   1 
ATOM   9972  O O   . PHE D 4 153 ? 121.627 145.121 146.713 1.00 152.93 ? 153 PHE H O   1 
ATOM   9973  C CB  . PHE D 4 153 ? 119.889 146.925 144.828 1.00 126.67 ? 153 PHE H CB  1 
ATOM   9974  C CG  . PHE D 4 153 ? 119.087 146.296 143.728 1.00 106.68 ? 153 PHE H CG  1 
ATOM   9975  C CD1 . PHE D 4 153 ? 119.502 145.154 143.082 1.00 107.51 ? 153 PHE H CD1 1 
ATOM   9976  C CD2 . PHE D 4 153 ? 117.912 146.873 143.315 1.00 117.89 ? 153 PHE H CD2 1 
ATOM   9977  C CE1 . PHE D 4 153 ? 118.763 144.604 142.035 1.00 157.10 ? 153 PHE H CE1 1 
ATOM   9978  C CE2 . PHE D 4 153 ? 117.167 146.322 142.278 1.00 147.80 ? 153 PHE H CE2 1 
ATOM   9979  C CZ  . PHE D 4 153 ? 117.579 145.182 141.654 1.00 130.93 ? 153 PHE H CZ  1 
ATOM   9980  N N   . PRO D 4 154 ? 119.934 143.832 145.968 1.00 121.87 ? 154 PRO H N   1 
ATOM   9981  C CA  . PRO D 4 154 ? 118.535 143.534 145.646 1.00 140.60 ? 154 PRO H CA  1 
ATOM   9982  C C   . PRO D 4 154 ? 117.633 143.426 146.881 1.00 201.02 ? 154 PRO H C   1 
ATOM   9983  O O   . PRO D 4 154 ? 118.075 143.764 147.997 1.00 169.73 ? 154 PRO H O   1 
ATOM   9984  C CB  . PRO D 4 154 ? 118.567 142.182 144.947 1.00 136.89 ? 154 PRO H CB  1 
ATOM   9985  C CG  . PRO D 4 154 ? 120.046 141.902 144.744 1.00 180.43 ? 154 PRO H CG  1 
ATOM   9986  C CD  . PRO D 4 154 ? 120.725 142.611 145.890 1.00 190.29 ? 154 PRO H CD  1 
ATOM   9987  N N   . GLU D 4 155 ? 116.388 142.931 146.632 1.00 167.18 ? 155 GLU H N   1 
ATOM   9988  C CA  . GLU D 4 155 ? 115.229 143.011 147.524 1.00 155.68 ? 155 GLU H CA  1 
ATOM   9989  C C   . GLU D 4 155 ? 115.477 142.577 148.971 1.00 177.21 ? 155 GLU H C   1 
ATOM   9990  O O   . GLU D 4 155 ? 115.062 143.302 149.879 1.00 230.95 ? 155 GLU H O   1 
ATOM   9991  C CB  . GLU D 4 155 ? 114.081 142.211 146.911 1.00 227.02 ? 155 GLU H CB  1 
ATOM   9992  C CG  . GLU D 4 155 ? 112.884 141.922 147.827 1.00 355.44 ? 155 GLU H CG  1 
ATOM   9993  C CD  . GLU D 4 155 ? 112.146 143.100 148.458 1.00 357.07 ? 155 GLU H CD  1 
ATOM   9994  O OE1 . GLU D 4 155 ? 112.052 144.163 147.811 1.00 325.27 ? 155 GLU H OE1 1 
ATOM   9995  O OE2 . GLU D 4 155 ? 111.641 142.939 149.600 1.00 377.57 ? 155 GLU H OE2 1 
ATOM   9996  N N   . PRO D 4 156 ? 116.104 141.411 149.265 1.00 153.37 ? 156 PRO H N   1 
ATOM   9997  C CA  . PRO D 4 156 ? 116.078 140.855 150.633 1.00 162.92 ? 156 PRO H CA  1 
ATOM   9998  C C   . PRO D 4 156 ? 117.151 141.485 151.524 1.00 132.20 ? 156 PRO H C   1 
ATOM   9999  O O   . PRO D 4 156 ? 118.337 141.248 151.344 1.00 147.80 ? 156 PRO H O   1 
ATOM   10000 C CB  . PRO D 4 156 ? 116.332 139.368 150.412 1.00 163.55 ? 156 PRO H CB  1 
ATOM   10001 C CG  . PRO D 4 156 ? 117.227 139.360 149.147 1.00 191.14 ? 156 PRO H CG  1 
ATOM   10002 C CD  . PRO D 4 156 ? 116.867 140.586 148.318 1.00 114.20 ? 156 PRO H CD  1 
ATOM   10003 N N   . VAL D 4 157 ? 116.697 142.327 152.451 1.00 129.90 ? 157 VAL H N   1 
ATOM   10004 C CA  . VAL D 4 157 ? 117.472 142.816 153.583 1.00 125.31 ? 157 VAL H CA  1 
ATOM   10005 C C   . VAL D 4 157 ? 116.690 142.429 154.827 1.00 134.19 ? 157 VAL H C   1 
ATOM   10006 O O   . VAL D 4 157 ? 115.465 142.432 154.821 1.00 202.32 ? 157 VAL H O   1 
ATOM   10007 C CB  . VAL D 4 157 ? 117.785 144.345 153.538 1.00 129.28 ? 157 VAL H CB  1 
ATOM   10008 C CG1 . VAL D 4 157 ? 116.644 145.266 153.869 1.00 128.16 ? 157 VAL H CG1 1 
ATOM   10009 C CG2 . VAL D 4 157 ? 118.898 144.769 154.467 1.00 175.23 ? 157 VAL H CG2 1 
ATOM   10010 N N   . THR D 4 158 ? 117.425 142.104 155.884 1.00 177.80 ? 158 THR H N   1 
ATOM   10011 C CA  . THR D 4 158 ? 116.872 141.595 157.119 1.00 196.78 ? 158 THR H CA  1 
ATOM   10012 C C   . THR D 4 158 ? 117.237 142.584 158.215 1.00 163.35 ? 158 THR H C   1 
ATOM   10013 O O   . THR D 4 158 ? 118.332 143.130 158.220 1.00 191.55 ? 158 THR H O   1 
ATOM   10014 C CB  . THR D 4 158 ? 117.397 140.181 157.400 1.00 209.92 ? 158 THR H CB  1 
ATOM   10015 O OG1 . THR D 4 158 ? 117.265 139.395 156.210 1.00 215.84 ? 158 THR H OG1 1 
ATOM   10016 C CG2 . THR D 4 158 ? 116.673 139.509 158.545 1.00 275.66 ? 158 THR H CG2 1 
ATOM   10017 N N   . VAL D 4 159 ? 116.305 142.805 159.140 1.00 172.67 ? 159 VAL H N   1 
ATOM   10018 C CA  . VAL D 4 159 ? 116.595 143.557 160.348 1.00 189.78 ? 159 VAL H CA  1 
ATOM   10019 C C   . VAL D 4 159 ? 116.133 142.723 161.540 1.00 225.73 ? 159 VAL H C   1 
ATOM   10020 O O   . VAL D 4 159 ? 115.038 142.147 161.541 1.00 257.12 ? 159 VAL H O   1 
ATOM   10021 C CB  . VAL D 4 159 ? 115.929 144.944 160.349 1.00 173.79 ? 159 VAL H CB  1 
ATOM   10022 C CG1 . VAL D 4 159 ? 116.303 145.741 161.594 1.00 138.09 ? 159 VAL H CG1 1 
ATOM   10023 C CG2 . VAL D 4 159 ? 116.235 145.715 159.070 1.00 153.39 ? 159 VAL H CG2 1 
ATOM   10024 N N   . THR D 4 160 ? 117.014 142.677 162.545 1.00 188.34 ? 160 THR H N   1 
ATOM   10025 C CA  . THR D 4 160 ? 116.687 142.226 163.882 1.00 202.90 ? 160 THR H CA  1 
ATOM   10026 C C   . THR D 4 160 ? 117.302 143.228 164.846 1.00 191.64 ? 160 THR H C   1 
ATOM   10027 O O   . THR D 4 160 ? 118.311 143.848 164.527 1.00 182.80 ? 160 THR H O   1 
ATOM   10028 C CB  . THR D 4 160 ? 117.183 140.794 164.147 1.00 297.67 ? 160 THR H CB  1 
ATOM   10029 O OG1 . THR D 4 160 ? 118.607 140.720 164.015 1.00 276.59 ? 160 THR H OG1 1 
ATOM   10030 C CG2 . THR D 4 160 ? 116.552 139.775 163.220 1.00 337.21 ? 160 THR H CG2 1 
ATOM   10031 N N   . TRP D 4 161 ? 116.688 143.360 166.024 1.00 213.00 ? 161 TRP H N   1 
ATOM   10032 C CA  . TRP D 4 161 ? 117.123 144.336 167.004 1.00 230.86 ? 161 TRP H CA  1 
ATOM   10033 C C   . TRP D 4 161 ? 117.809 143.651 168.190 1.00 278.67 ? 161 TRP H C   1 
ATOM   10034 O O   . TRP D 4 161 ? 117.276 142.676 168.733 1.00 263.20 ? 161 TRP H O   1 
ATOM   10035 C CB  . TRP D 4 161 ? 115.918 145.169 167.437 1.00 207.46 ? 161 TRP H CB  1 
ATOM   10036 C CG  . TRP D 4 161 ? 115.396 146.102 166.375 1.00 169.99 ? 161 TRP H CG  1 
ATOM   10037 C CD1 . TRP D 4 161 ? 114.494 145.840 165.387 1.00 182.61 ? 161 TRP H CD1 1 
ATOM   10038 C CD2 . TRP D 4 161 ? 115.755 147.486 166.216 1.00 177.70 ? 161 TRP H CD2 1 
ATOM   10039 N NE1 . TRP D 4 161 ? 114.261 146.955 164.633 1.00 187.17 ? 161 TRP H NE1 1 
ATOM   10040 C CE2 . TRP D 4 161 ? 115.025 147.983 165.112 1.00 188.22 ? 161 TRP H CE2 1 
ATOM   10041 C CE3 . TRP D 4 161 ? 116.621 148.351 166.895 1.00 251.41 ? 161 TRP H CE3 1 
ATOM   10042 C CZ2 . TRP D 4 161 ? 115.130 149.305 164.680 1.00 179.18 ? 161 TRP H CZ2 1 
ATOM   10043 C CZ3 . TRP D 4 161 ? 116.733 149.654 166.462 1.00 268.12 ? 161 TRP H CZ3 1 
ATOM   10044 C CH2 . TRP D 4 161 ? 115.991 150.122 165.376 1.00 170.19 ? 161 TRP H CH2 1 
ATOM   10045 N N   . ASN D 4 162 ? 118.994 144.175 168.575 1.00 273.67 ? 162 ASN H N   1 
ATOM   10046 C CA  . ASN D 4 162 ? 119.850 143.624 169.622 1.00 258.07 ? 162 ASN H CA  1 
ATOM   10047 C C   . ASN D 4 162 ? 120.081 142.128 169.387 1.00 237.74 ? 162 ASN H C   1 
ATOM   10048 O O   . ASN D 4 162 ? 119.838 141.314 170.277 1.00 237.90 ? 162 ASN H O   1 
ATOM   10049 C CB  . ASN D 4 162 ? 119.288 143.957 171.016 1.00 265.27 ? 162 ASN H CB  1 
ATOM   10050 C CG  . ASN D 4 162 ? 119.519 145.393 171.444 1.00 276.45 ? 162 ASN H CG  1 
ATOM   10051 O OD1 . ASN D 4 162 ? 119.996 146.213 170.664 1.00 226.48 ? 162 ASN H OD1 1 
ATOM   10052 N ND2 . ASN D 4 162 ? 119.183 145.710 172.685 1.00 286.69 ? 162 ASN H ND2 1 
ATOM   10053 N N   . SER D 4 163 ? 120.544 141.784 168.174 1.00 237.39 ? 163 SER H N   1 
ATOM   10054 C CA  . SER D 4 163 ? 120.908 140.423 167.783 1.00 283.64 ? 163 SER H CA  1 
ATOM   10055 C C   . SER D 4 163 ? 119.757 139.419 167.972 1.00 229.51 ? 163 SER H C   1 
ATOM   10056 O O   . SER D 4 163 ? 119.989 138.264 168.316 1.00 228.32 ? 163 SER H O   1 
ATOM   10057 C CB  . SER D 4 163 ? 122.155 139.977 168.533 1.00 378.75 ? 163 SER H CB  1 
ATOM   10058 O OG  . SER D 4 163 ? 123.205 140.935 168.442 1.00 406.50 ? 163 SER H OG  1 
ATOM   10059 N N   . GLY D 4 164 ? 118.510 139.856 167.748 1.00 265.65 ? 164 GLY H N   1 
ATOM   10060 C CA  . GLY D 4 164 ? 117.332 139.013 167.911 1.00 285.82 ? 164 GLY H CA  1 
ATOM   10061 C C   . GLY D 4 164 ? 116.765 138.958 169.333 1.00 269.15 ? 164 GLY H C   1 
ATOM   10062 O O   . GLY D 4 164 ? 115.756 138.277 169.543 1.00 302.17 ? 164 GLY H O   1 
ATOM   10063 N N   . SER D 4 165 ? 117.386 139.668 170.294 1.00 271.35 ? 165 SER H N   1 
ATOM   10064 C CA  . SER D 4 165 ? 116.924 139.703 171.679 1.00 316.63 ? 165 SER H CA  1 
ATOM   10065 C C   . SER D 4 165 ? 115.586 140.438 171.803 1.00 337.42 ? 165 SER H C   1 
ATOM   10066 O O   . SER D 4 165 ? 114.714 139.986 172.548 1.00 325.98 ? 165 SER H O   1 
ATOM   10067 C CB  . SER D 4 165 ? 117.957 140.328 172.589 1.00 331.30 ? 165 SER H CB  1 
ATOM   10068 O OG  . SER D 4 165 ? 119.232 139.729 172.410 1.00 338.70 ? 165 SER H OG  1 
ATOM   10069 N N   . LEU D 4 166 ? 115.428 141.556 171.073 1.00 318.44 ? 166 LEU H N   1 
ATOM   10070 C CA  . LEU D 4 166 ? 114.187 142.326 171.051 1.00 272.91 ? 166 LEU H CA  1 
ATOM   10071 C C   . LEU D 4 166 ? 113.271 141.814 169.936 1.00 263.08 ? 166 LEU H C   1 
ATOM   10072 O O   . LEU D 4 166 ? 112.861 142.569 169.056 1.00 328.68 ? 166 LEU H O   1 
ATOM   10073 C CB  . LEU D 4 166 ? 114.522 143.812 170.859 1.00 272.23 ? 166 LEU H CB  1 
ATOM   10074 C CG  . LEU D 4 166 ? 115.255 144.504 172.003 1.00 315.36 ? 166 LEU H CG  1 
ATOM   10075 C CD1 . LEU D 4 166 ? 115.545 145.956 171.641 1.00 303.12 ? 166 LEU H CD1 1 
ATOM   10076 C CD2 . LEU D 4 166 ? 114.443 144.418 173.291 1.00 343.81 ? 166 LEU H CD2 1 
ATOM   10077 N N   . SER D 4 167 ? 112.925 140.519 169.989 1.00 315.12 ? 167 SER H N   1 
ATOM   10078 C CA  . SER D 4 167 ? 112.020 139.902 169.025 1.00 334.43 ? 167 SER H CA  1 
ATOM   10079 C C   . SER D 4 167 ? 110.551 140.241 169.319 1.00 279.94 ? 167 SER H C   1 
ATOM   10080 O O   . SER D 4 167 ? 109.690 139.876 168.516 1.00 275.91 ? 167 SER H O   1 
ATOM   10081 C CB  . SER D 4 167 ? 112.243 138.404 168.979 1.00 396.20 ? 167 SER H CB  1 
ATOM   10082 O OG  . SER D 4 167 ? 112.039 137.815 170.255 1.00 429.61 ? 167 SER H OG  1 
ATOM   10083 N N   . SER D 4 168 ? 110.268 140.924 170.453 1.00 253.56 ? 168 SER H N   1 
ATOM   10084 C CA  . SER D 4 168 ? 108.933 141.356 170.853 1.00 294.73 ? 168 SER H CA  1 
ATOM   10085 C C   . SER D 4 168 ? 108.725 142.848 170.573 1.00 278.45 ? 168 SER H C   1 
ATOM   10086 O O   . SER D 4 168 ? 109.535 143.685 170.980 1.00 264.90 ? 168 SER H O   1 
ATOM   10087 C CB  . SER D 4 168 ? 108.706 141.051 172.310 1.00 334.46 ? 168 SER H CB  1 
ATOM   10088 O OG  . SER D 4 168 ? 108.697 139.649 172.538 1.00 369.78 ? 168 SER H OG  1 
ATOM   10089 N N   . GLY D 4 169 ? 107.619 143.163 169.878 1.00 272.50 ? 169 GLY H N   1 
ATOM   10090 C CA  . GLY D 4 169 ? 107.231 144.531 169.581 1.00 253.15 ? 169 GLY H CA  1 
ATOM   10091 C C   . GLY D 4 169 ? 108.037 145.168 168.450 1.00 239.27 ? 169 GLY H C   1 
ATOM   10092 O O   . GLY D 4 169 ? 108.276 146.358 168.525 1.00 176.88 ? 169 GLY H O   1 
ATOM   10093 N N   . VAL D 4 170 ? 108.428 144.395 167.417 1.00 240.46 ? 170 VAL H N   1 
ATOM   10094 C CA  . VAL D 4 170 ? 109.121 144.899 166.235 1.00 190.58 ? 170 VAL H CA  1 
ATOM   10095 C C   . VAL D 4 170 ? 108.182 144.863 165.026 1.00 211.53 ? 170 VAL H C   1 
ATOM   10096 O O   . VAL D 4 170 ? 107.542 143.847 164.754 1.00 218.60 ? 170 VAL H O   1 
ATOM   10097 C CB  . VAL D 4 170 ? 110.399 144.096 165.933 1.00 179.19 ? 170 VAL H CB  1 
ATOM   10098 C CG1 . VAL D 4 170 ? 110.930 144.289 164.513 1.00 218.38 ? 170 VAL H CG1 1 
ATOM   10099 C CG2 . VAL D 4 170 ? 111.475 144.439 166.926 1.00 177.83 ? 170 VAL H CG2 1 
ATOM   10100 N N   . HIS D 4 171 ? 108.143 145.986 164.299 1.00 192.47 ? 171 HIS H N   1 
ATOM   10101 C CA  . HIS D 4 171 ? 107.475 146.119 163.016 1.00 180.01 ? 171 HIS H CA  1 
ATOM   10102 C C   . HIS D 4 171 ? 108.517 146.502 161.967 1.00 180.29 ? 171 HIS H C   1 
ATOM   10103 O O   . HIS D 4 171 ? 109.184 147.526 162.127 1.00 195.47 ? 171 HIS H O   1 
ATOM   10104 C CB  . HIS D 4 171 ? 106.410 147.222 163.070 1.00 165.01 ? 171 HIS H CB  1 
ATOM   10105 C CG  . HIS D 4 171 ? 105.357 147.031 164.096 1.00 149.40 ? 171 HIS H CG  1 
ATOM   10106 N ND1 . HIS D 4 171 ? 105.505 147.441 165.398 1.00 192.19 ? 171 HIS H ND1 1 
ATOM   10107 C CD2 . HIS D 4 171 ? 104.133 146.477 164.007 1.00 228.43 ? 171 HIS H CD2 1 
ATOM   10108 C CE1 . HIS D 4 171 ? 104.399 147.138 166.071 1.00 311.23 ? 171 HIS H CE1 1 
ATOM   10109 N NE2 . HIS D 4 171 ? 103.553 146.550 165.244 1.00 283.36 ? 171 HIS H NE2 1 
ATOM   10110 N N   . THR D 4 172 ? 108.660 145.687 160.917 1.00 148.83 ? 172 THR H N   1 
ATOM   10111 C CA  . THR D 4 172 ? 109.514 146.030 159.794 1.00 149.11 ? 172 THR H CA  1 
ATOM   10112 C C   . THR D 4 172 ? 108.647 146.132 158.547 1.00 146.28 ? 172 THR H C   1 
ATOM   10113 O O   . THR D 4 172 ? 107.989 145.173 158.140 1.00 182.94 ? 172 THR H O   1 
ATOM   10114 C CB  . THR D 4 172 ? 110.632 145.008 159.575 1.00 183.42 ? 172 THR H CB  1 
ATOM   10115 O OG1 . THR D 4 172 ? 111.394 144.922 160.781 1.00 167.73 ? 172 THR H OG1 1 
ATOM   10116 C CG2 . THR D 4 172 ? 111.533 145.365 158.407 1.00 168.83 ? 172 THR H CG2 1 
ATOM   10117 N N   . PHE D 4 173 ? 108.666 147.307 157.941 1.00 109.94 ? 173 PHE H N   1 
ATOM   10118 C CA  . PHE D 4 173 ? 107.750 147.609 156.865 1.00 115.78 ? 173 PHE H CA  1 
ATOM   10119 C C   . PHE D 4 173 ? 108.340 147.102 155.555 1.00 98.24  ? 173 PHE H C   1 
ATOM   10120 O O   . PHE D 4 173 ? 109.527 147.275 155.303 1.00 169.99 ? 173 PHE H O   1 
ATOM   10121 C CB  . PHE D 4 173 ? 107.472 149.107 156.870 1.00 143.07 ? 173 PHE H CB  1 
ATOM   10122 C CG  . PHE D 4 173 ? 107.031 149.630 158.215 1.00 129.78 ? 173 PHE H CG  1 
ATOM   10123 C CD1 . PHE D 4 173 ? 105.732 149.449 158.639 1.00 127.71 ? 173 PHE H CD1 1 
ATOM   10124 C CD2 . PHE D 4 173 ? 107.929 150.299 159.049 1.00 137.40 ? 173 PHE H CD2 1 
ATOM   10125 C CE1 . PHE D 4 173 ? 105.347 149.945 159.879 1.00 208.86 ? 173 PHE H CE1 1 
ATOM   10126 C CE2 . PHE D 4 173 ? 107.539 150.800 160.279 1.00 128.84 ? 173 PHE H CE2 1 
ATOM   10127 C CZ  . PHE D 4 173 ? 106.246 150.619 160.693 1.00 172.66 ? 173 PHE H CZ  1 
ATOM   10128 N N   . PRO D 4 174 ? 107.549 146.453 154.686 1.00 110.71 ? 174 PRO H N   1 
ATOM   10129 C CA  . PRO D 4 174 ? 107.962 146.104 153.337 1.00 139.31 ? 174 PRO H CA  1 
ATOM   10130 C C   . PRO D 4 174 ? 108.722 147.190 152.590 1.00 152.60 ? 174 PRO H C   1 
ATOM   10131 O O   . PRO D 4 174 ? 108.473 148.381 152.777 1.00 137.79 ? 174 PRO H O   1 
ATOM   10132 C CB  . PRO D 4 174 ? 106.623 145.906 152.610 1.00 196.78 ? 174 PRO H CB  1 
ATOM   10133 C CG  . PRO D 4 174 ? 105.745 145.326 153.669 1.00 240.49 ? 174 PRO H CG  1 
ATOM   10134 C CD  . PRO D 4 174 ? 106.196 145.990 154.951 1.00 182.63 ? 174 PRO H CD  1 
ATOM   10135 N N   . ALA D 4 175 ? 109.650 146.748 151.731 1.00 166.27 ? 175 ALA H N   1 
ATOM   10136 C CA  . ALA D 4 175 ? 110.484 147.657 150.960 1.00 150.29 ? 175 ALA H CA  1 
ATOM   10137 C C   . ALA D 4 175 ? 109.721 148.292 149.795 1.00 172.56 ? 175 ALA H C   1 
ATOM   10138 O O   . ALA D 4 175 ? 108.815 147.684 149.214 1.00 144.76 ? 175 ALA H O   1 
ATOM   10139 C CB  . ALA D 4 175 ? 111.691 146.946 150.446 1.00 188.22 ? 175 ALA H CB  1 
ATOM   10140 N N   . VAL D 4 176 ? 110.126 149.541 149.489 1.00 181.93 ? 176 VAL H N   1 
ATOM   10141 C CA  . VAL D 4 176 ? 109.604 150.366 148.414 1.00 156.65 ? 176 VAL H CA  1 
ATOM   10142 C C   . VAL D 4 176 ? 110.743 150.516 147.411 1.00 186.95 ? 176 VAL H C   1 
ATOM   10143 O O   . VAL D 4 176 ? 111.863 150.842 147.820 1.00 244.92 ? 176 VAL H O   1 
ATOM   10144 C CB  . VAL D 4 176 ? 109.166 151.756 148.933 1.00 183.29 ? 176 VAL H CB  1 
ATOM   10145 C CG1 . VAL D 4 176 ? 108.456 152.557 147.854 1.00 246.49 ? 176 VAL H CG1 1 
ATOM   10146 C CG2 . VAL D 4 176 ? 108.297 151.693 150.176 1.00 215.42 ? 176 VAL H CG2 1 
ATOM   10147 N N   . LEU D 4 177 ? 110.461 150.310 146.114 1.00 177.60 ? 177 LEU H N   1 
ATOM   10148 C CA  . LEU D 4 177 ? 111.472 150.406 145.073 1.00 178.66 ? 177 LEU H CA  1 
ATOM   10149 C C   . LEU D 4 177 ? 111.403 151.768 144.380 1.00 218.99 ? 177 LEU H C   1 
ATOM   10150 O O   . LEU D 4 177 ? 110.346 152.158 143.883 1.00 204.19 ? 177 LEU H O   1 
ATOM   10151 C CB  . LEU D 4 177 ? 111.215 149.257 144.102 1.00 208.90 ? 177 LEU H CB  1 
ATOM   10152 C CG  . LEU D 4 177 ? 112.122 149.183 142.880 1.00 248.95 ? 177 LEU H CG  1 
ATOM   10153 C CD1 . LEU D 4 177 ? 113.577 149.074 143.301 1.00 253.35 ? 177 LEU H CD1 1 
ATOM   10154 C CD2 . LEU D 4 177 ? 111.734 147.997 142.002 1.00 272.16 ? 177 LEU H CD2 1 
ATOM   10155 N N   . GLN D 4 178 ? 112.546 152.477 144.348 1.00 271.66 ? 178 GLN H N   1 
ATOM   10156 C CA  . GLN D 4 178 ? 112.660 153.824 143.793 1.00 293.11 ? 178 GLN H CA  1 
ATOM   10157 C C   . GLN D 4 178 ? 113.932 153.930 142.955 1.00 299.65 ? 178 GLN H C   1 
ATOM   10158 O O   . GLN D 4 178 ? 115.009 153.608 143.452 1.00 340.12 ? 178 GLN H O   1 
ATOM   10159 C CB  . GLN D 4 178 ? 112.701 154.865 144.914 1.00 254.13 ? 178 GLN H CB  1 
ATOM   10160 C CG  . GLN D 4 178 ? 111.353 155.104 145.573 1.00 288.61 ? 178 GLN H CG  1 
ATOM   10161 C CD  . GLN D 4 178 ? 110.352 155.723 144.626 1.00 328.07 ? 178 GLN H CD  1 
ATOM   10162 O OE1 . GLN D 4 178 ? 110.340 156.937 144.423 1.00 279.87 ? 178 GLN H OE1 1 
ATOM   10163 N NE2 . GLN D 4 178 ? 109.499 154.895 144.037 1.00 379.45 ? 178 GLN H NE2 1 
ATOM   10164 N N   . SER D 4 179 ? 113.801 154.377 141.693 1.00 272.39 ? 179 SER H N   1 
ATOM   10165 C CA  . SER D 4 179 ? 114.924 154.549 140.778 1.00 314.05 ? 179 SER H CA  1 
ATOM   10166 C C   . SER D 4 179 ? 115.864 153.333 140.803 1.00 265.83 ? 179 SER H C   1 
ATOM   10167 O O   . SER D 4 179 ? 117.085 153.490 140.867 1.00 295.01 ? 179 SER H O   1 
ATOM   10168 C CB  . SER D 4 179 ? 115.651 155.872 141.049 1.00 381.18 ? 179 SER H CB  1 
ATOM   10169 O OG  . SER D 4 179 ? 116.244 155.939 142.345 1.00 349.47 ? 179 SER H OG  1 
ATOM   10170 N N   . ASP D 4 180 ? 115.269 152.127 140.756 1.00 205.36 ? 180 ASP H N   1 
ATOM   10171 C CA  . ASP D 4 180 ? 115.958 150.834 140.764 1.00 246.31 ? 180 ASP H CA  1 
ATOM   10172 C C   . ASP D 4 180 ? 116.870 150.629 141.992 1.00 235.18 ? 180 ASP H C   1 
ATOM   10173 O O   . ASP D 4 180 ? 117.870 149.906 141.885 1.00 228.41 ? 180 ASP H O   1 
ATOM   10174 C CB  . ASP D 4 180 ? 116.678 150.598 139.421 1.00 312.57 ? 180 ASP H CB  1 
ATOM   10175 C CG  . ASP D 4 180 ? 115.763 150.592 138.201 1.00 389.83 ? 180 ASP H CG  1 
ATOM   10176 O OD1 . ASP D 4 180 ? 114.537 150.393 138.363 1.00 405.51 ? 180 ASP H OD1 1 
ATOM   10177 O OD2 . ASP D 4 180 ? 116.287 150.793 137.092 1.00 468.05 ? 180 ASP H OD2 1 
ATOM   10178 N N   . LEU D 4 181 ? 116.509 151.226 143.156 1.00 224.38 ? 181 LEU H N   1 
ATOM   10179 C CA  . LEU D 4 181 ? 117.080 150.942 144.478 1.00 187.28 ? 181 LEU H CA  1 
ATOM   10180 C C   . LEU D 4 181 ? 115.960 150.879 145.532 1.00 201.92 ? 181 LEU H C   1 
ATOM   10181 O O   . LEU D 4 181 ? 115.003 151.645 145.479 1.00 223.17 ? 181 LEU H O   1 
ATOM   10182 C CB  . LEU D 4 181 ? 118.071 152.047 144.851 1.00 165.88 ? 181 LEU H CB  1 
ATOM   10183 C CG  . LEU D 4 181 ? 119.248 152.273 143.910 1.00 266.43 ? 181 LEU H CG  1 
ATOM   10184 C CD1 . LEU D 4 181 ? 120.009 153.531 144.307 1.00 320.65 ? 181 LEU H CD1 1 
ATOM   10185 C CD2 . LEU D 4 181 ? 120.180 151.072 143.895 1.00 267.42 ? 181 LEU H CD2 1 
ATOM   10186 N N   . TYR D 4 182 ? 116.071 149.970 146.508 1.00 180.86 ? 182 TYR H N   1 
ATOM   10187 C CA  . TYR D 4 182 ? 115.029 149.733 147.504 1.00 150.60 ? 182 TYR H CA  1 
ATOM   10188 C C   . TYR D 4 182 ? 115.229 150.625 148.731 1.00 147.69 ? 182 TYR H C   1 
ATOM   10189 O O   . TYR D 4 182 ? 116.354 151.040 149.032 1.00 197.33 ? 182 TYR H O   1 
ATOM   10190 C CB  . TYR D 4 182 ? 115.031 148.269 147.959 1.00 125.22 ? 182 TYR H CB  1 
ATOM   10191 C CG  . TYR D 4 182 ? 114.604 147.322 146.857 1.00 121.90 ? 182 TYR H CG  1 
ATOM   10192 C CD1 . TYR D 4 182 ? 113.276 147.084 146.576 1.00 133.70 ? 182 TYR H CD1 1 
ATOM   10193 C CD2 . TYR D 4 182 ? 115.541 146.665 146.080 1.00 222.86 ? 182 TYR H CD2 1 
ATOM   10194 C CE1 . TYR D 4 182 ? 112.885 146.221 145.566 1.00 165.50 ? 182 TYR H CE1 1 
ATOM   10195 C CE2 . TYR D 4 182 ? 115.164 145.798 145.063 1.00 266.80 ? 182 TYR H CE2 1 
ATOM   10196 C CZ  . TYR D 4 182 ? 113.829 145.567 144.799 1.00 188.52 ? 182 TYR H CZ  1 
ATOM   10197 O OH  . TYR D 4 182 ? 113.438 144.719 143.802 1.00 185.86 ? 182 TYR H OH  1 
ATOM   10198 N N   . THR D 4 183 ? 114.120 150.903 149.433 1.00 150.01 ? 183 THR H N   1 
ATOM   10199 C CA  . THR D 4 183 ? 114.102 151.593 150.717 1.00 171.55 ? 183 THR H CA  1 
ATOM   10200 C C   . THR D 4 183 ? 113.184 150.819 151.662 1.00 147.90 ? 183 THR H C   1 
ATOM   10201 O O   . THR D 4 183 ? 112.109 150.388 151.242 1.00 164.83 ? 183 THR H O   1 
ATOM   10202 C CB  . THR D 4 183 ? 113.595 153.046 150.608 1.00 267.82 ? 183 THR H CB  1 
ATOM   10203 O OG1 . THR D 4 183 ? 114.213 153.747 149.525 1.00 289.16 ? 183 THR H OG1 1 
ATOM   10204 C CG2 . THR D 4 183 ? 113.830 153.839 151.878 1.00 287.59 ? 183 THR H CG2 1 
ATOM   10205 N N   . LEU D 4 184 ? 113.615 150.665 152.919 1.00 158.07 ? 184 LEU H N   1 
ATOM   10206 C CA  . LEU D 4 184 ? 112.908 149.889 153.928 1.00 150.31 ? 184 LEU H CA  1 
ATOM   10207 C C   . LEU D 4 184 ? 113.133 150.546 155.276 1.00 124.43 ? 184 LEU H C   1 
ATOM   10208 O O   . LEU D 4 184 ? 114.085 151.303 155.434 1.00 191.85 ? 184 LEU H O   1 
ATOM   10209 C CB  . LEU D 4 184 ? 113.477 148.473 153.895 1.00 136.85 ? 184 LEU H CB  1 
ATOM   10210 C CG  . LEU D 4 184 ? 113.114 147.547 155.058 1.00 151.59 ? 184 LEU H CG  1 
ATOM   10211 C CD1 . LEU D 4 184 ? 112.891 146.112 154.570 1.00 208.54 ? 184 LEU H CD1 1 
ATOM   10212 C CD2 . LEU D 4 184 ? 114.175 147.584 156.152 1.00 130.95 ? 184 LEU H CD2 1 
ATOM   10213 N N   . SER D 4 185 ? 112.245 150.313 156.234 1.00 113.69 ? 185 SER H N   1 
ATOM   10214 C CA  . SER D 4 185 ? 112.443 150.845 157.566 1.00 137.47 ? 185 SER H CA  1 
ATOM   10215 C C   . SER D 4 185 ? 111.906 149.880 158.608 1.00 125.71 ? 185 SER H C   1 
ATOM   10216 O O   . SER D 4 185 ? 110.971 149.128 158.364 1.00 186.98 ? 185 SER H O   1 
ATOM   10217 C CB  . SER D 4 185 ? 111.847 152.239 157.699 1.00 149.81 ? 185 SER H CB  1 
ATOM   10218 O OG  . SER D 4 185 ? 110.528 152.283 157.174 1.00 168.86 ? 185 SER H OG  1 
ATOM   10219 N N   . SER D 4 186 ? 112.521 149.914 159.779 1.00 119.95 ? 186 SER H N   1 
ATOM   10220 C CA  . SER D 4 186 ? 112.222 148.973 160.836 1.00 128.21 ? 186 SER H CA  1 
ATOM   10221 C C   . SER D 4 186 ? 112.061 149.778 162.109 1.00 146.80 ? 186 SER H C   1 
ATOM   10222 O O   . SER D 4 186 ? 112.695 150.829 162.264 1.00 196.46 ? 186 SER H O   1 
ATOM   10223 C CB  . SER D 4 186 ? 113.297 147.908 160.985 1.00 161.20 ? 186 SER H CB  1 
ATOM   10224 O OG  . SER D 4 186 ? 112.941 146.969 161.995 1.00 169.85 ? 186 SER H OG  1 
ATOM   10225 N N   . SER D 4 187 ? 111.226 149.248 163.006 1.00 156.46 ? 187 SER H N   1 
ATOM   10226 C CA  . SER D 4 187 ? 110.827 149.977 164.195 1.00 179.19 ? 187 SER H CA  1 
ATOM   10227 C C   . SER D 4 187 ? 110.604 149.023 165.355 1.00 187.07 ? 187 SER H C   1 
ATOM   10228 O O   . SER D 4 187 ? 110.222 147.874 165.155 1.00 196.34 ? 187 SER H O   1 
ATOM   10229 C CB  . SER D 4 187 ? 109.605 150.772 163.917 1.00 198.27 ? 187 SER H CB  1 
ATOM   10230 O OG  . SER D 4 187 ? 108.473 149.940 163.812 1.00 190.07 ? 187 SER H OG  1 
ATOM   10231 N N   . VAL D 4 188 ? 110.858 149.552 166.553 1.00 184.79 ? 188 VAL H N   1 
ATOM   10232 C CA  . VAL D 4 188 ? 110.773 148.806 167.788 1.00 189.90 ? 188 VAL H CA  1 
ATOM   10233 C C   . VAL D 4 188 ? 110.309 149.778 168.871 1.00 209.30 ? 188 VAL H C   1 
ATOM   10234 O O   . VAL D 4 188 ? 110.564 150.973 168.773 1.00 183.88 ? 188 VAL H O   1 
ATOM   10235 C CB  . VAL D 4 188 ? 112.133 148.160 168.089 1.00 196.06 ? 188 VAL H CB  1 
ATOM   10236 C CG1 . VAL D 4 188 ? 113.234 149.187 168.311 1.00 176.03 ? 188 VAL H CG1 1 
ATOM   10237 C CG2 . VAL D 4 188 ? 112.048 147.208 169.270 1.00 262.01 ? 188 VAL H CG2 1 
ATOM   10238 N N   . THR D 4 189 ? 109.619 149.263 169.895 1.00 236.11 ? 189 THR H N   1 
ATOM   10239 C CA  . THR D 4 189 ? 109.175 150.075 171.018 1.00 247.16 ? 189 THR H CA  1 
ATOM   10240 C C   . THR D 4 189 ? 109.637 149.407 172.314 1.00 272.87 ? 189 THR H C   1 
ATOM   10241 O O   . THR D 4 189 ? 109.517 148.186 172.472 1.00 244.57 ? 189 THR H O   1 
ATOM   10242 C CB  . THR D 4 189 ? 107.664 150.337 170.943 1.00 287.61 ? 189 THR H CB  1 
ATOM   10243 O OG1 . THR D 4 189 ? 107.383 151.098 169.767 1.00 296.57 ? 189 THR H OG1 1 
ATOM   10244 C CG2 . THR D 4 189 ? 107.142 151.099 172.139 1.00 318.76 ? 189 THR H CG2 1 
ATOM   10245 N N   . VAL D 4 190 ? 110.166 150.243 173.228 1.00 288.18 ? 190 VAL H N   1 
ATOM   10246 C CA  . VAL D 4 190 ? 110.779 149.793 174.470 1.00 295.76 ? 190 VAL H CA  1 
ATOM   10247 C C   . VAL D 4 190 ? 110.318 150.685 175.627 1.00 276.31 ? 190 VAL H C   1 
ATOM   10248 O O   . VAL D 4 190 ? 109.843 151.804 175.404 1.00 225.42 ? 190 VAL H O   1 
ATOM   10249 C CB  . VAL D 4 190 ? 112.319 149.770 174.363 1.00 284.99 ? 190 VAL H CB  1 
ATOM   10250 C CG1 . VAL D 4 190 ? 112.802 148.704 173.392 1.00 256.39 ? 190 VAL H CG1 1 
ATOM   10251 C CG2 . VAL D 4 190 ? 112.898 151.130 173.994 1.00 277.67 ? 190 VAL H CG2 1 
ATOM   10252 N N   . PRO D 4 191 ? 110.437 150.226 176.900 1.00 263.11 ? 191 PRO H N   1 
ATOM   10253 C CA  . PRO D 4 191 ? 110.190 151.094 178.055 1.00 273.30 ? 191 PRO H CA  1 
ATOM   10254 C C   . PRO D 4 191 ? 111.097 152.327 178.064 1.00 319.74 ? 191 PRO H C   1 
ATOM   10255 O O   . PRO D 4 191 ? 112.268 152.243 177.678 1.00 366.84 ? 191 PRO H O   1 
ATOM   10256 C CB  . PRO D 4 191 ? 110.496 150.193 179.266 1.00 318.07 ? 191 PRO H CB  1 
ATOM   10257 C CG  . PRO D 4 191 ? 110.303 148.788 178.738 1.00 312.84 ? 191 PRO H CG  1 
ATOM   10258 C CD  . PRO D 4 191 ? 110.801 148.856 177.311 1.00 282.58 ? 191 PRO H CD  1 
ATOM   10259 N N   . SER D 4 192 ? 110.545 153.465 178.512 1.00 355.43 ? 192 SER H N   1 
ATOM   10260 C CA  . SER D 4 192 ? 111.280 154.723 178.620 1.00 375.23 ? 192 SER H CA  1 
ATOM   10261 C C   . SER D 4 192 ? 112.469 154.638 179.586 1.00 363.83 ? 192 SER H C   1 
ATOM   10262 O O   . SER D 4 192 ? 113.386 155.449 179.478 1.00 335.34 ? 192 SER H O   1 
ATOM   10263 C CB  . SER D 4 192 ? 110.348 155.859 179.003 1.00 371.21 ? 192 SER H CB  1 
ATOM   10264 O OG  . SER D 4 192 ? 109.598 155.537 180.166 1.00 357.88 ? 192 SER H OG  1 
ATOM   10265 N N   . SER D 4 193 ? 112.452 153.673 180.525 1.00 348.21 ? 193 SER H N   1 
ATOM   10266 C CA  . SER D 4 193 ? 113.600 153.333 181.361 1.00 358.51 ? 193 SER H CA  1 
ATOM   10267 C C   . SER D 4 193 ? 114.768 152.736 180.564 1.00 350.74 ? 193 SER H C   1 
ATOM   10268 O O   . SER D 4 193 ? 115.927 152.989 180.902 1.00 368.33 ? 193 SER H O   1 
ATOM   10269 C CB  . SER D 4 193 ? 113.178 152.392 182.469 1.00 367.84 ? 193 SER H CB  1 
ATOM   10270 O OG  . SER D 4 193 ? 112.626 151.190 181.946 1.00 359.25 ? 193 SER H OG  1 
ATOM   10271 N N   . THR D 4 194 ? 114.458 151.945 179.520 1.00 323.64 ? 194 THR H N   1 
ATOM   10272 C CA  . THR D 4 194 ? 115.440 151.157 178.783 1.00 318.93 ? 194 THR H CA  1 
ATOM   10273 C C   . THR D 4 194 ? 116.300 152.042 177.871 1.00 298.98 ? 194 THR H C   1 
ATOM   10274 O O   . THR D 4 194 ? 117.521 151.976 177.976 1.00 345.74 ? 194 THR H O   1 
ATOM   10275 C CB  . THR D 4 194 ? 114.758 149.990 178.039 1.00 317.59 ? 194 THR H CB  1 
ATOM   10276 O OG1 . THR D 4 194 ? 114.575 148.936 178.989 1.00 253.32 ? 194 THR H OG1 1 
ATOM   10277 C CG2 . THR D 4 194 ? 115.526 149.444 176.849 1.00 316.18 ? 194 THR H CG2 1 
ATOM   10278 N N   . TRP D 4 195 ? 115.704 152.850 176.978 1.00 252.94 ? 195 TRP H N   1 
ATOM   10279 C CA  . TRP D 4 195 ? 116.439 153.314 175.798 1.00 275.42 ? 195 TRP H CA  1 
ATOM   10280 C C   . TRP D 4 195 ? 117.693 154.136 176.142 1.00 330.77 ? 195 TRP H C   1 
ATOM   10281 O O   . TRP D 4 195 ? 118.770 153.760 175.682 1.00 325.89 ? 195 TRP H O   1 
ATOM   10282 C CB  . TRP D 4 195 ? 115.545 154.066 174.799 1.00 293.63 ? 195 TRP H CB  1 
ATOM   10283 C CG  . TRP D 4 195 ? 116.347 154.871 173.803 1.00 275.73 ? 195 TRP H CG  1 
ATOM   10284 C CD1 . TRP D 4 195 ? 117.398 154.426 173.050 1.00 239.65 ? 195 TRP H CD1 1 
ATOM   10285 C CD2 . TRP D 4 195 ? 116.165 156.261 173.455 1.00 300.83 ? 195 TRP H CD2 1 
ATOM   10286 N NE1 . TRP D 4 195 ? 117.884 155.432 172.262 1.00 273.96 ? 195 TRP H NE1 1 
ATOM   10287 C CE2 . TRP D 4 195 ? 117.149 156.568 172.485 1.00 307.89 ? 195 TRP H CE2 1 
ATOM   10288 C CE3 . TRP D 4 195 ? 115.274 157.268 173.860 1.00 348.78 ? 195 TRP H CE3 1 
ATOM   10289 C CZ2 . TRP D 4 195 ? 117.254 157.840 171.920 1.00 382.17 ? 195 TRP H CZ2 1 
ATOM   10290 C CZ3 . TRP D 4 195 ? 115.384 158.524 173.303 1.00 374.01 ? 195 TRP H CZ3 1 
ATOM   10291 C CH2 . TRP D 4 195 ? 116.361 158.803 172.345 1.00 393.60 ? 195 TRP H CH2 1 
ATOM   10292 N N   . PRO D 4 196 ? 117.658 155.252 176.921 1.00 359.96 ? 196 PRO H N   1 
ATOM   10293 C CA  . PRO D 4 196 ? 118.902 155.944 177.294 1.00 378.59 ? 196 PRO H CA  1 
ATOM   10294 C C   . PRO D 4 196 ? 119.875 155.161 178.192 1.00 386.63 ? 196 PRO H C   1 
ATOM   10295 O O   . PRO D 4 196 ? 121.040 155.552 178.285 1.00 363.76 ? 196 PRO H O   1 
ATOM   10296 C CB  . PRO D 4 196 ? 118.409 157.205 178.036 1.00 361.28 ? 196 PRO H CB  1 
ATOM   10297 C CG  . PRO D 4 196 ? 116.960 157.350 177.623 1.00 323.16 ? 196 PRO H CG  1 
ATOM   10298 C CD  . PRO D 4 196 ? 116.468 155.927 177.472 1.00 317.32 ? 196 PRO H CD  1 
ATOM   10299 N N   . SER D 4 197 ? 119.399 154.072 178.835 1.00 392.01 ? 197 SER H N   1 
ATOM   10300 C CA  . SER D 4 197 ? 120.141 153.293 179.821 1.00 385.82 ? 197 SER H CA  1 
ATOM   10301 C C   . SER D 4 197 ? 120.903 152.102 179.222 1.00 385.55 ? 197 SER H C   1 
ATOM   10302 O O   . SER D 4 197 ? 121.812 151.593 179.878 1.00 411.39 ? 197 SER H O   1 
ATOM   10303 C CB  . SER D 4 197 ? 119.194 152.802 180.902 1.00 362.46 ? 197 SER H CB  1 
ATOM   10304 O OG  . SER D 4 197 ? 118.404 153.864 181.429 1.00 299.49 ? 197 SER H OG  1 
ATOM   10305 N N   . GLU D 4 198 ? 120.545 151.657 178.000 1.00 373.31 ? 198 GLU H N   1 
ATOM   10306 C CA  . GLU D 4 198 ? 120.961 150.366 177.459 1.00 376.80 ? 198 GLU H CA  1 
ATOM   10307 C C   . GLU D 4 198 ? 121.363 150.478 175.982 1.00 355.83 ? 198 GLU H C   1 
ATOM   10308 O O   . GLU D 4 198 ? 121.071 151.466 175.307 1.00 292.73 ? 198 GLU H O   1 
ATOM   10309 C CB  . GLU D 4 198 ? 119.825 149.347 177.597 1.00 359.89 ? 198 GLU H CB  1 
ATOM   10310 C CG  . GLU D 4 198 ? 119.306 149.142 179.015 1.00 335.61 ? 198 GLU H CG  1 
ATOM   10311 C CD  . GLU D 4 198 ? 118.316 147.994 179.143 1.00 372.16 ? 198 GLU H CD  1 
ATOM   10312 O OE1 . GLU D 4 198 ? 118.736 146.842 178.915 1.00 373.44 ? 198 GLU H OE1 1 
ATOM   10313 O OE2 . GLU D 4 198 ? 117.129 148.249 179.465 1.00 410.79 ? 198 GLU H OE2 1 
ATOM   10314 N N   . THR D 4 199 ? 122.044 149.434 175.483 1.00 348.87 ? 199 THR H N   1 
ATOM   10315 C CA  . THR D 4 199 ? 122.351 149.289 174.065 1.00 356.35 ? 199 THR H CA  1 
ATOM   10316 C C   . THR D 4 199 ? 121.064 149.030 173.282 1.00 358.32 ? 199 THR H C   1 
ATOM   10317 O O   . THR D 4 199 ? 120.272 148.171 173.676 1.00 366.95 ? 199 THR H O   1 
ATOM   10318 C CB  . THR D 4 199 ? 123.339 148.137 173.812 1.00 396.97 ? 199 THR H CB  1 
ATOM   10319 O OG1 . THR D 4 199 ? 124.545 148.384 174.539 1.00 402.75 ? 199 THR H OG1 1 
ATOM   10320 C CG2 . THR D 4 199 ? 123.688 147.942 172.350 1.00 427.81 ? 199 THR H CG2 1 
ATOM   10321 N N   . VAL D 4 200 ? 120.864 149.769 172.175 1.00 330.71 ? 200 VAL H N   1 
ATOM   10322 C CA  . VAL D 4 200 ? 119.879 149.406 171.158 1.00 281.96 ? 200 VAL H CA  1 
ATOM   10323 C C   . VAL D 4 200 ? 120.521 149.519 169.773 1.00 249.58 ? 200 VAL H C   1 
ATOM   10324 O O   . VAL D 4 200 ? 121.039 150.584 169.437 1.00 187.36 ? 200 VAL H O   1 
ATOM   10325 C CB  . VAL D 4 200 ? 118.597 150.261 171.224 1.00 262.71 ? 200 VAL H CB  1 
ATOM   10326 C CG1 . VAL D 4 200 ? 117.573 149.765 170.213 1.00 297.98 ? 200 VAL H CG1 1 
ATOM   10327 C CG2 . VAL D 4 200 ? 117.979 150.299 172.613 1.00 249.16 ? 200 VAL H CG2 1 
ATOM   10328 N N   . THR D 4 201 ? 120.469 148.427 168.980 1.00 232.97 ? 201 THR H N   1 
ATOM   10329 C CA  . THR D 4 201 ? 120.985 148.394 167.612 1.00 225.16 ? 201 THR H CA  1 
ATOM   10330 C C   . THR D 4 201 ? 120.010 147.716 166.651 1.00 242.27 ? 201 THR H C   1 
ATOM   10331 O O   . THR D 4 201 ? 119.472 146.661 166.973 1.00 246.74 ? 201 THR H O   1 
ATOM   10332 C CB  . THR D 4 201 ? 122.306 147.624 167.488 1.00 237.77 ? 201 THR H CB  1 
ATOM   10333 O OG1 . THR D 4 201 ? 122.163 146.306 168.028 1.00 241.41 ? 201 THR H OG1 1 
ATOM   10334 C CG2 . THR D 4 201 ? 123.449 148.327 168.184 1.00 280.56 ? 201 THR H CG2 1 
ATOM   10335 N N   . CYS D 4 202 ? 119.795 148.319 165.468 1.00 225.05 ? 202 CYS H N   1 
ATOM   10336 C CA  . CYS D 4 202 ? 119.298 147.560 164.332 1.00 217.87 ? 202 CYS H CA  1 
ATOM   10337 C C   . CYS D 4 202 ? 120.480 146.798 163.714 1.00 185.17 ? 202 CYS H C   1 
ATOM   10338 O O   . CYS D 4 202 ? 121.409 147.412 163.190 1.00 167.24 ? 202 CYS H O   1 
ATOM   10339 C CB  . CYS D 4 202 ? 118.549 148.428 163.321 1.00 253.38 ? 202 CYS H CB  1 
ATOM   10340 S SG  . CYS D 4 202 ? 119.443 149.818 162.586 1.00 304.73 ? 202 CYS H SG  1 
ATOM   10341 N N   . ASN D 4 203 ? 120.424 145.453 163.794 1.00 213.61 ? 203 ASN H N   1 
ATOM   10342 C CA  . ASN D 4 203 ? 121.417 144.555 163.212 1.00 226.04 ? 203 ASN H CA  1 
ATOM   10343 C C   . ASN D 4 203 ? 121.056 144.245 161.754 1.00 175.67 ? 203 ASN H C   1 
ATOM   10344 O O   . ASN D 4 203 ? 120.673 143.123 161.427 1.00 195.23 ? 203 ASN H O   1 
ATOM   10345 C CB  . ASN D 4 203 ? 121.555 143.246 164.009 1.00 274.86 ? 203 ASN H CB  1 
ATOM   10346 C CG  . ASN D 4 203 ? 121.991 143.381 165.459 1.00 289.97 ? 203 ASN H CG  1 
ATOM   10347 O OD1 . ASN D 4 203 ? 121.523 144.245 166.198 1.00 244.34 ? 203 ASN H OD1 1 
ATOM   10348 N ND2 . ASN D 4 203 ? 122.881 142.505 165.900 1.00 293.01 ? 203 ASN H ND2 1 
ATOM   10349 N N   . VAL D 4 204 ? 121.205 145.248 160.872 1.00 168.49 ? 204 VAL H N   1 
ATOM   10350 C CA  . VAL D 4 204 ? 120.882 145.133 159.452 1.00 180.97 ? 204 VAL H CA  1 
ATOM   10351 C C   . VAL D 4 204 ? 121.832 144.152 158.774 1.00 181.05 ? 204 VAL H C   1 
ATOM   10352 O O   . VAL D 4 204 ? 123.018 144.160 159.067 1.00 243.63 ? 204 VAL H O   1 
ATOM   10353 C CB  . VAL D 4 204 ? 120.929 146.485 158.728 1.00 183.11 ? 204 VAL H CB  1 
ATOM   10354 C CG1 . VAL D 4 204 ? 120.732 146.323 157.219 1.00 186.95 ? 204 VAL H CG1 1 
ATOM   10355 C CG2 . VAL D 4 204 ? 119.905 147.435 159.342 1.00 249.58 ? 204 VAL H CG2 1 
ATOM   10356 N N   . ALA D 4 205 ? 121.278 143.308 157.899 1.00 188.47 ? 205 ALA H N   1 
ATOM   10357 C CA  . ALA D 4 205 ? 122.016 142.240 157.257 1.00 215.19 ? 205 ALA H CA  1 
ATOM   10358 C C   . ALA D 4 205 ? 121.519 142.069 155.832 1.00 181.44 ? 205 ALA H C   1 
ATOM   10359 O O   . ALA D 4 205 ? 120.326 142.117 155.587 1.00 288.76 ? 205 ALA H O   1 
ATOM   10360 C CB  . ALA D 4 205 ? 121.868 140.952 158.047 1.00 262.02 ? 205 ALA H CB  1 
ATOM   10361 N N   . HIS D 4 206 ? 122.450 141.831 154.910 1.00 192.30 ? 206 HIS H N   1 
ATOM   10362 C CA  . HIS D 4 206 ? 122.163 141.824 153.488 1.00 179.93 ? 206 HIS H CA  1 
ATOM   10363 C C   . HIS D 4 206 ? 122.834 140.602 152.840 1.00 187.81 ? 206 HIS H C   1 
ATOM   10364 O O   . HIS D 4 206 ? 124.017 140.668 152.541 1.00 185.90 ? 206 HIS H O   1 
ATOM   10365 C CB  . HIS D 4 206 ? 122.568 143.197 152.931 1.00 138.38 ? 206 HIS H CB  1 
ATOM   10366 C CG  . HIS D 4 206 ? 122.202 143.409 151.499 1.00 178.72 ? 206 HIS H CG  1 
ATOM   10367 N ND1 . HIS D 4 206 ? 122.509 142.572 150.445 1.00 220.25 ? 206 HIS H ND1 1 
ATOM   10368 C CD2 . HIS D 4 206 ? 121.535 144.418 150.964 1.00 180.56 ? 206 HIS H CD2 1 
ATOM   10369 C CE1 . HIS D 4 206 ? 122.018 143.084 149.339 1.00 179.83 ? 206 HIS H CE1 1 
ATOM   10370 N NE2 . HIS D 4 206 ? 121.432 144.191 149.634 1.00 146.10 ? 206 HIS H NE2 1 
ATOM   10371 N N   . PRO D 4 207 ? 122.121 139.474 152.613 1.00 224.77 ? 207 PRO H N   1 
ATOM   10372 C CA  . PRO D 4 207 ? 122.694 138.274 151.989 1.00 273.58 ? 207 PRO H CA  1 
ATOM   10373 C C   . PRO D 4 207 ? 123.429 138.433 150.658 1.00 269.71 ? 207 PRO H C   1 
ATOM   10374 O O   . PRO D 4 207 ? 124.423 137.739 150.424 1.00 349.60 ? 207 PRO H O   1 
ATOM   10375 C CB  . PRO D 4 207 ? 121.465 137.380 151.716 1.00 284.36 ? 207 PRO H CB  1 
ATOM   10376 C CG  . PRO D 4 207 ? 120.502 137.770 152.807 1.00 334.74 ? 207 PRO H CG  1 
ATOM   10377 C CD  . PRO D 4 207 ? 120.714 139.259 152.965 1.00 285.59 ? 207 PRO H CD  1 
ATOM   10378 N N   . ALA D 4 208 ? 122.935 139.333 149.799 1.00 199.14 ? 208 ALA H N   1 
ATOM   10379 C CA  . ALA D 4 208 ? 123.412 139.414 148.425 1.00 236.44 ? 208 ALA H CA  1 
ATOM   10380 C C   . ALA D 4 208 ? 124.660 140.301 148.264 1.00 221.83 ? 208 ALA H C   1 
ATOM   10381 O O   . ALA D 4 208 ? 125.243 140.274 147.185 1.00 212.34 ? 208 ALA H O   1 
ATOM   10382 C CB  . ALA D 4 208 ? 122.259 139.845 147.546 1.00 269.36 ? 208 ALA H CB  1 
ATOM   10383 N N   . SER D 4 209 ? 125.081 141.072 149.288 1.00 214.27 ? 209 SER H N   1 
ATOM   10384 C CA  . SER D 4 209 ? 126.374 141.758 149.261 1.00 211.02 ? 209 SER H CA  1 
ATOM   10385 C C   . SER D 4 209 ? 127.144 141.669 150.587 1.00 232.62 ? 209 SER H C   1 
ATOM   10386 O O   . SER D 4 209 ? 128.043 142.483 150.805 1.00 211.53 ? 209 SER H O   1 
ATOM   10387 C CB  . SER D 4 209 ? 126.216 143.205 148.806 1.00 204.40 ? 209 SER H CB  1 
ATOM   10388 O OG  . SER D 4 209 ? 125.707 144.079 149.805 1.00 209.11 ? 209 SER H OG  1 
ATOM   10389 N N   . SER D 4 210 ? 126.801 140.689 151.453 1.00 259.31 ? 210 SER H N   1 
ATOM   10390 C CA  . SER D 4 210 ? 127.590 140.237 152.599 1.00 326.14 ? 210 SER H CA  1 
ATOM   10391 C C   . SER D 4 210 ? 127.833 141.300 153.686 1.00 295.42 ? 210 SER H C   1 
ATOM   10392 O O   . SER D 4 210 ? 128.642 141.054 154.585 1.00 355.77 ? 210 SER H O   1 
ATOM   10393 C CB  . SER D 4 210 ? 128.888 139.608 152.112 1.00 390.21 ? 210 SER H CB  1 
ATOM   10394 O OG  . SER D 4 210 ? 128.621 138.489 151.275 1.00 387.56 ? 210 SER H OG  1 
ATOM   10395 N N   . THR D 4 211 ? 127.144 142.459 153.647 1.00 214.69 ? 211 THR H N   1 
ATOM   10396 C CA  . THR D 4 211 ? 127.346 143.518 154.634 1.00 242.94 ? 211 THR H CA  1 
ATOM   10397 C C   . THR D 4 211 ? 126.452 143.304 155.857 1.00 224.49 ? 211 THR H C   1 
ATOM   10398 O O   . THR D 4 211 ? 125.253 143.055 155.703 1.00 289.99 ? 211 THR H O   1 
ATOM   10399 C CB  . THR D 4 211 ? 127.076 144.917 154.062 1.00 290.94 ? 211 THR H CB  1 
ATOM   10400 O OG1 . THR D 4 211 ? 125.775 144.921 153.474 1.00 353.22 ? 211 THR H OG1 1 
ATOM   10401 C CG2 . THR D 4 211 ? 128.106 145.336 153.038 1.00 275.35 ? 211 THR H CG2 1 
ATOM   10402 N N   . LYS D 4 212 ? 127.056 143.422 157.051 1.00 239.30 ? 212 LYS H N   1 
ATOM   10403 C CA  . LYS D 4 212 ? 126.376 143.298 158.334 1.00 279.10 ? 212 LYS H CA  1 
ATOM   10404 C C   . LYS D 4 212 ? 126.745 144.511 159.190 1.00 248.02 ? 212 LYS H C   1 
ATOM   10405 O O   . LYS D 4 212 ? 127.927 144.792 159.370 1.00 257.39 ? 212 LYS H O   1 
ATOM   10406 C CB  . LYS D 4 212 ? 126.760 141.978 159.016 1.00 301.29 ? 212 LYS H CB  1 
ATOM   10407 C CG  . LYS D 4 212 ? 126.410 140.713 158.238 1.00 307.68 ? 212 LYS H CG  1 
ATOM   10408 C CD  . LYS D 4 212 ? 126.849 139.421 158.924 1.00 327.08 ? 212 LYS H CD  1 
ATOM   10409 C CE  . LYS D 4 212 ? 126.159 139.123 160.244 1.00 360.96 ? 212 LYS H CE  1 
ATOM   10410 N NZ  . LYS D 4 212 ? 124.712 138.832 160.081 1.00 390.12 ? 212 LYS H NZ  1 
ATOM   10411 N N   . VAL D 4 213 ? 125.737 145.228 159.712 1.00 235.23 ? 213 VAL H N   1 
ATOM   10412 C CA  . VAL D 4 213 ? 125.937 146.539 160.316 1.00 236.89 ? 213 VAL H CA  1 
ATOM   10413 C C   . VAL D 4 213 ? 125.022 146.700 161.531 1.00 245.28 ? 213 VAL H C   1 
ATOM   10414 O O   . VAL D 4 213 ? 123.838 146.363 161.469 1.00 316.54 ? 213 VAL H O   1 
ATOM   10415 C CB  . VAL D 4 213 ? 125.677 147.674 159.304 1.00 272.19 ? 213 VAL H CB  1 
ATOM   10416 C CG1 . VAL D 4 213 ? 125.998 149.032 159.921 1.00 264.04 ? 213 VAL H CG1 1 
ATOM   10417 C CG2 . VAL D 4 213 ? 126.419 147.477 157.980 1.00 265.50 ? 213 VAL H CG2 1 
ATOM   10418 N N   . ASP D 4 214 ? 125.583 147.248 162.625 1.00 234.46 ? 214 ASP H N   1 
ATOM   10419 C CA  . ASP D 4 214 ? 124.918 147.367 163.919 1.00 283.10 ? 214 ASP H CA  1 
ATOM   10420 C C   . ASP D 4 214 ? 124.952 148.830 164.383 1.00 251.08 ? 214 ASP H C   1 
ATOM   10421 O O   . ASP D 4 214 ? 125.713 149.189 165.281 1.00 312.23 ? 214 ASP H O   1 
ATOM   10422 C CB  . ASP D 4 214 ? 125.557 146.428 164.961 1.00 377.21 ? 214 ASP H CB  1 
ATOM   10423 C CG  . ASP D 4 214 ? 125.688 144.964 164.555 1.00 405.84 ? 214 ASP H CG  1 
ATOM   10424 O OD1 . ASP D 4 214 ? 124.739 144.437 163.944 1.00 403.47 ? 214 ASP H OD1 1 
ATOM   10425 O OD2 . ASP D 4 214 ? 126.744 144.359 164.854 1.00 408.56 ? 214 ASP H OD2 1 
ATOM   10426 N N   . LYS D 4 215 ? 124.120 149.683 163.773 1.00 243.54 ? 215 LYS H N   1 
ATOM   10427 C CA  . LYS D 4 215 ? 124.014 151.087 164.144 1.00 256.03 ? 215 LYS H CA  1 
ATOM   10428 C C   . LYS D 4 215 ? 123.329 151.227 165.506 1.00 229.89 ? 215 LYS H C   1 
ATOM   10429 O O   . LYS D 4 215 ? 122.240 150.695 165.698 1.00 185.31 ? 215 LYS H O   1 
ATOM   10430 C CB  . LYS D 4 215 ? 123.218 151.850 163.079 1.00 290.51 ? 215 LYS H CB  1 
ATOM   10431 C CG  . LYS D 4 215 ? 123.969 152.168 161.792 1.00 268.15 ? 215 LYS H CG  1 
ATOM   10432 C CD  . LYS D 4 215 ? 125.114 153.148 161.960 1.00 283.87 ? 215 LYS H CD  1 
ATOM   10433 C CE  . LYS D 4 215 ? 124.694 154.517 162.466 1.00 341.70 ? 215 LYS H CE  1 
ATOM   10434 N NZ  . LYS D 4 215 ? 125.873 155.400 162.639 1.00 352.97 ? 215 LYS H NZ  1 
ATOM   10435 N N   . LYS D 4 216 ? 123.971 151.952 166.436 1.00 241.59 ? 216 LYS H N   1 
ATOM   10436 C CA  . LYS D 4 216 ? 123.400 152.229 167.749 1.00 298.74 ? 216 LYS H CA  1 
ATOM   10437 C C   . LYS D 4 216 ? 122.488 153.454 167.688 1.00 282.54 ? 216 LYS H C   1 
ATOM   10438 O O   . LYS D 4 216 ? 122.829 154.440 167.033 1.00 244.87 ? 216 LYS H O   1 
ATOM   10439 C CB  . LYS D 4 216 ? 124.504 152.458 168.786 1.00 354.45 ? 216 LYS H CB  1 
ATOM   10440 C CG  . LYS D 4 216 ? 125.254 151.203 169.202 1.00 385.93 ? 216 LYS H CG  1 
ATOM   10441 C CD  . LYS D 4 216 ? 126.281 151.443 170.292 1.00 391.49 ? 216 LYS H CD  1 
ATOM   10442 C CE  . LYS D 4 216 ? 126.900 150.165 170.822 1.00 423.68 ? 216 LYS H CE  1 
ATOM   10443 N NZ  . LYS D 4 216 ? 127.749 149.483 169.813 1.00 443.74 ? 216 LYS H NZ  1 
ATOM   10444 N N   . ILE D 4 217 ? 121.341 153.386 168.389 1.00 250.58 ? 217 ILE H N   1 
ATOM   10445 C CA  . ILE D 4 217 ? 120.352 154.457 168.388 1.00 252.05 ? 217 ILE H CA  1 
ATOM   10446 C C   . ILE D 4 217 ? 120.685 155.435 169.521 1.00 273.74 ? 217 ILE H C   1 
ATOM   10447 O O   . ILE D 4 217 ? 120.257 155.239 170.664 1.00 244.28 ? 217 ILE H O   1 
ATOM   10448 C CB  . ILE D 4 217 ? 118.908 153.917 168.507 1.00 263.33 ? 217 ILE H CB  1 
ATOM   10449 C CG1 . ILE D 4 217 ? 118.643 152.674 167.645 1.00 246.70 ? 217 ILE H CG1 1 
ATOM   10450 C CG2 . ILE D 4 217 ? 117.895 155.031 168.222 1.00 309.50 ? 217 ILE H CG2 1 
ATOM   10451 C CD1 . ILE D 4 217 ? 118.931 152.826 166.176 1.00 214.78 ? 217 ILE H CD1 1 
ATOM   10452 N N   . VAL D 4 218 ? 121.441 156.496 169.185 1.00 307.55 ? 218 VAL H N   1 
ATOM   10453 C CA  . VAL D 4 218 ? 121.958 157.459 170.152 1.00 328.49 ? 218 VAL H CA  1 
ATOM   10454 C C   . VAL D 4 218 ? 121.069 158.710 170.159 1.00 300.70 ? 218 VAL H C   1 
ATOM   10455 O O   . VAL D 4 218 ? 120.710 159.199 169.086 1.00 270.64 ? 218 VAL H O   1 
ATOM   10456 C CB  . VAL D 4 218 ? 123.429 157.809 169.843 1.00 376.63 ? 218 VAL H CB  1 
ATOM   10457 C CG1 . VAL D 4 218 ? 124.007 158.840 170.812 1.00 389.11 ? 218 VAL H CG1 1 
ATOM   10458 C CG2 . VAL D 4 218 ? 124.307 156.562 169.813 1.00 412.29 ? 218 VAL H CG2 1 
ATOM   10459 N N   . PRO D 4 219 ? 120.689 159.272 171.342 1.00 316.72 ? 219 PRO H N   1 
ATOM   10460 C CA  . PRO D 4 219 ? 119.897 160.512 171.410 1.00 307.57 ? 219 PRO H CA  1 
ATOM   10461 C C   . PRO D 4 219 ? 120.508 161.744 170.738 1.00 300.07 ? 219 PRO H C   1 
ATOM   10462 O O   . PRO D 4 219 ? 121.722 161.824 170.562 1.00 334.86 ? 219 PRO H O   1 
ATOM   10463 C CB  . PRO D 4 219 ? 119.759 160.802 172.923 1.00 307.35 ? 219 PRO H CB  1 
ATOM   10464 C CG  . PRO D 4 219 ? 120.014 159.473 173.602 1.00 315.82 ? 219 PRO H CG  1 
ATOM   10465 C CD  . PRO D 4 219 ? 120.976 158.744 172.690 1.00 322.71 ? 219 PRO H CD  1 
ATOM   10466 N N   . ARG D 4 220 ? 119.647 162.707 170.376 1.00 288.17 ? 220 ARG H N   1 
ATOM   10467 C CA  . ARG D 4 220 ? 120.084 163.939 169.729 1.00 342.69 ? 220 ARG H CA  1 
ATOM   10468 C C   . ARG D 4 220 ? 120.734 164.863 170.771 1.00 337.57 ? 220 ARG H C   1 
ATOM   10469 O O   . ARG D 4 220 ? 119.994 165.439 171.593 1.00 265.24 ? 220 ARG H O   1 
ATOM   10470 C CB  . ARG D 4 220 ? 118.912 164.613 169.005 1.00 337.24 ? 220 ARG H CB  1 
ATOM   10471 C CG  . ARG D 4 220 ? 118.284 163.750 167.921 1.00 356.87 ? 220 ARG H CG  1 
ATOM   10472 C CD  . ARG D 4 220 ? 117.136 164.457 167.223 1.00 383.14 ? 220 ARG H CD  1 
ATOM   10473 N NE  . ARG D 4 220 ? 117.556 165.534 166.332 1.00 368.95 ? 220 ARG H NE  1 
ATOM   10474 C CZ  . ARG D 4 220 ? 117.968 165.380 165.073 1.00 384.83 ? 220 ARG H CZ  1 
ATOM   10475 N NH1 . ARG D 4 220 ? 118.040 164.177 164.525 1.00 400.14 ? 220 ARG H NH1 1 
ATOM   10476 N NH2 . ARG D 4 220 ? 118.304 166.438 164.348 1.00 360.08 ? 220 ARG H NH2 1 
HETATM 10477 C C1  . NAG E 5 .   ? 108.959 77.060  150.010 1.00 256.68 ? 701 NAG A C1  1 
HETATM 10478 C C2  . NAG E 5 .   ? 108.190 77.784  151.122 1.00 257.38 ? 701 NAG A C2  1 
HETATM 10479 C C3  . NAG E 5 .   ? 109.044 77.830  152.388 1.00 318.68 ? 701 NAG A C3  1 
HETATM 10480 C C4  . NAG E 5 .   ? 109.492 76.425  152.772 1.00 309.12 ? 701 NAG A C4  1 
HETATM 10481 C C5  . NAG E 5 .   ? 110.219 75.784  151.586 1.00 297.83 ? 701 NAG A C5  1 
HETATM 10482 C C6  . NAG E 5 .   ? 110.682 74.382  151.914 1.00 315.97 ? 701 NAG A C6  1 
HETATM 10483 C C7  . NAG E 5 .   ? 106.605 79.397  150.101 1.00 271.51 ? 701 NAG A C7  1 
HETATM 10484 C C8  . NAG E 5 .   ? 106.366 80.827  149.719 1.00 295.63 ? 701 NAG A C8  1 
HETATM 10485 N N2  . NAG E 5 .   ? 107.747 79.124  150.759 1.00 245.91 ? 701 NAG A N2  1 
HETATM 10486 O O3  . NAG E 5 .   ? 108.341 78.444  153.464 1.00 409.29 ? 701 NAG A O3  1 
HETATM 10487 O O4  . NAG E 5 .   ? 110.360 76.511  153.905 1.00 274.25 ? 701 NAG A O4  1 
HETATM 10488 O O5  . NAG E 5 .   ? 109.369 75.745  150.403 1.00 237.64 ? 701 NAG A O5  1 
HETATM 10489 O O6  . NAG E 5 .   ? 109.593 73.509  152.249 1.00 353.37 ? 701 NAG A O6  1 
HETATM 10490 O O7  . NAG E 5 .   ? 105.806 78.510  149.811 1.00 263.49 ? 701 NAG A O7  1 
HETATM 10491 C C1  . NAG F 5 .   ? 80.718  93.447  137.727 1.00 301.97 ? 702 NAG A C1  1 
HETATM 10492 C C2  . NAG F 5 .   ? 81.723  94.394  138.394 1.00 332.30 ? 702 NAG A C2  1 
HETATM 10493 C C3  . NAG F 5 .   ? 81.305  94.762  139.829 1.00 381.77 ? 702 NAG A C3  1 
HETATM 10494 C C4  . NAG F 5 .   ? 79.821  95.120  139.931 1.00 350.57 ? 702 NAG A C4  1 
HETATM 10495 C C5  . NAG F 5 .   ? 78.978  94.014  139.288 1.00 325.69 ? 702 NAG A C5  1 
HETATM 10496 C C6  . NAG F 5 .   ? 77.482  94.267  139.321 1.00 286.77 ? 702 NAG A C6  1 
HETATM 10497 C C7  . NAG F 5 .   ? 83.483  92.667  138.864 1.00 289.05 ? 702 NAG A C7  1 
HETATM 10498 C C8  . NAG F 5 .   ? 84.829  92.162  138.428 1.00 259.01 ? 702 NAG A C8  1 
HETATM 10499 N N2  . NAG F 5 .   ? 83.079  93.857  138.366 1.00 330.32 ? 702 NAG A N2  1 
HETATM 10500 O O3  . NAG F 5 .   ? 82.104  95.843  140.305 1.00 405.66 ? 702 NAG A O3  1 
HETATM 10501 O O4  . NAG F 5 .   ? 79.476  95.277  141.310 1.00 261.91 ? 702 NAG A O4  1 
HETATM 10502 O O5  . NAG F 5 .   ? 79.369  93.885  137.900 1.00 290.40 ? 702 NAG A O5  1 
HETATM 10503 O O6  . NAG F 5 .   ? 77.116  95.480  138.662 1.00 293.45 ? 702 NAG A O6  1 
HETATM 10504 O O7  . NAG F 5 .   ? 82.785  92.015  139.637 1.00 229.42 ? 702 NAG A O7  1 
HETATM 10505 C C1  . NAG G 5 .   ? 123.613 65.047  127.535 1.00 401.27 ? 703 NAG A C1  1 
HETATM 10506 C C2  . NAG G 5 .   ? 124.710 63.994  127.461 1.00 412.80 ? 703 NAG A C2  1 
HETATM 10507 C C3  . NAG G 5 .   ? 126.006 64.673  127.021 1.00 471.32 ? 703 NAG A C3  1 
HETATM 10508 C C4  . NAG G 5 .   ? 125.806 65.384  125.683 1.00 514.06 ? 703 NAG A C4  1 
HETATM 10509 C C5  . NAG G 5 .   ? 124.582 66.311  125.718 1.00 502.98 ? 703 NAG A C5  1 
HETATM 10510 C C6  . NAG G 5 .   ? 124.184 66.826  124.344 1.00 523.31 ? 703 NAG A C6  1 
HETATM 10511 C C7  . NAG G 5 .   ? 124.153 62.176  129.031 1.00 413.24 ? 703 NAG A C7  1 
HETATM 10512 C C8  . NAG G 5 .   ? 124.552 61.454  130.285 1.00 449.89 ? 703 NAG A C8  1 
HETATM 10513 N N2  . NAG G 5 .   ? 124.874 63.261  128.704 1.00 410.94 ? 703 NAG A N2  1 
HETATM 10514 O O3  . NAG G 5 .   ? 127.079 63.739  126.936 1.00 463.08 ? 703 NAG A O3  1 
HETATM 10515 O O4  . NAG G 5 .   ? 126.990 66.134  125.407 1.00 539.16 ? 703 NAG A O4  1 
HETATM 10516 O O5  . NAG G 5 .   ? 123.424 65.620  126.241 1.00 420.86 ? 703 NAG A O5  1 
HETATM 10517 O O6  . NAG G 5 .   ? 123.081 67.747  124.387 1.00 482.75 ? 703 NAG A O6  1 
HETATM 10518 O O7  . NAG G 5 .   ? 123.209 61.794  128.342 1.00 348.25 ? 703 NAG A O7  1 
HETATM 10519 C C1  . NAG H 5 .   ? 124.080 94.378  135.212 1.00 370.29 ? 704 NAG A C1  1 
HETATM 10520 C C2  . NAG H 5 .   ? 125.334 93.717  134.639 1.00 430.83 ? 704 NAG A C2  1 
HETATM 10521 C C3  . NAG H 5 .   ? 126.535 94.654  134.809 1.00 480.18 ? 704 NAG A C3  1 
HETATM 10522 C C4  . NAG H 5 .   ? 126.245 96.015  134.175 1.00 471.33 ? 704 NAG A C4  1 
HETATM 10523 C C5  . NAG H 5 .   ? 124.950 96.609  134.731 1.00 424.78 ? 704 NAG A C5  1 
HETATM 10524 C C6  . NAG H 5 .   ? 124.496 97.861  133.997 1.00 419.22 ? 704 NAG A C6  1 
HETATM 10525 C C7  . NAG H 5 .   ? 125.745 92.030  136.442 1.00 372.57 ? 704 NAG A C7  1 
HETATM 10526 C C8  . NAG H 5 .   ? 125.919 90.563  136.715 1.00 297.25 ? 704 NAG A C8  1 
HETATM 10527 N N2  . NAG H 5 .   ? 125.568 92.376  135.157 1.00 414.05 ? 704 NAG A N2  1 
HETATM 10528 O O3  . NAG H 5 .   ? 127.714 94.101  134.231 1.00 519.07 ? 704 NAG A O3  1 
HETATM 10529 O O4  . NAG H 5 .   ? 127.334 96.894  134.453 1.00 517.09 ? 704 NAG A O4  1 
HETATM 10530 O O5  . NAG H 5 .   ? 123.873 95.655  134.600 1.00 363.98 ? 704 NAG A O5  1 
HETATM 10531 O O6  . NAG H 5 .   ? 125.502 98.882  133.942 1.00 448.79 ? 704 NAG A O6  1 
HETATM 10532 O O7  . NAG H 5 .   ? 125.760 92.861  137.347 1.00 357.43 ? 704 NAG A O7  1 
# 
