data_8KDG
# 
_entry.id   8KDG 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8KDG         pdb_00008kdg 10.2210/pdb8kdg/pdb 
WWPDB D_1300040163 ?            ?                   
EMDB  EMD-37135    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1  'Structure model' 1 0 2025-02-12 ? 
2  'EM metadata'     1 0 2025-02-12 ? 
3  FSC               1 0 2025-02-12 ? 
4  'Half map'        1 0 2025-02-12 1 
5  'Half map'        1 0 2025-02-12 2 
6  Image             1 0 2025-02-12 ? 
7  Mask              1 0 2025-02-12 ? 
8  'Primary map'     1 0 2025-02-12 ? 
9  'Structure model' 1 1 2025-02-26 ? 
10 'EM metadata'     1 1 2025-02-26 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 Mask              repository 'Initial release' ? ? 
8 8 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 9  'Structure model' 'Data collection'      
2 9  'Structure model' 'Database references'  
3 10 'EM metadata'     'Database references'  
4 10 'EM metadata'     'Experimental summary' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 9  'Structure model' citation        
2 9  'Structure model' citation_author 
3 9  'Structure model' em_admin        
4 10 'EM metadata'     citation        
5 10 'EM metadata'     citation_author 
6 10 'EM metadata'     em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  9  'Structure model' '_citation.country'                 
2  9  'Structure model' '_citation.journal_abbrev'          
3  9  'Structure model' '_citation.journal_id_CSD'          
4  9  'Structure model' '_citation.journal_id_ISSN'         
5  9  'Structure model' '_citation.journal_volume'          
6  9  'Structure model' '_citation.page_first'              
7  9  'Structure model' '_citation.page_last'               
8  9  'Structure model' '_citation.pdbx_database_id_DOI'    
9  9  'Structure model' '_citation.pdbx_database_id_PubMed' 
10 9  'Structure model' '_citation.title'                   
11 9  'Structure model' '_citation.year'                    
12 9  'Structure model' '_em_admin.last_update'             
13 10 'EM metadata'     '_citation.country'                 
14 10 'EM metadata'     '_citation.journal_abbrev'          
15 10 'EM metadata'     '_citation.journal_id_CSD'          
16 10 'EM metadata'     '_citation.journal_id_ISSN'         
17 10 'EM metadata'     '_citation.journal_volume'          
18 10 'EM metadata'     '_citation.page_first'              
19 10 'EM metadata'     '_citation.page_last'               
20 10 'EM metadata'     '_citation.pdbx_database_id_DOI'    
21 10 'EM metadata'     '_citation.pdbx_database_id_PubMed' 
22 10 'EM metadata'     '_citation.title'                   
23 10 'EM metadata'     '_citation.year'                    
24 10 'EM metadata'     '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8KDG 
_pdbx_database_status.recvd_initial_deposition_date   2023-08-09 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'Structure of LAT1-CD98hc-Fab170 in complex with BCH, consensus map' EMD-37135 'associated EM volume' 
EMDB 'Structure of LAT1-CD98hc in complex with BCH, focused on TMD'       EMD-37136 'focused EM volume'    
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              ri.yon.df@yokohama-cu.ac.jp 
_pdbx_contact_author.name_first         Yongchan 
_pdbx_contact_author.name_last          Lee 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1507-805X 
# 
_audit_author.name               'Lee, Y.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                1635 
_citation.page_last                 1635 
_citation.title                     'Structural basis of anticancer drug recognition and amino acid transport by LAT1.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-56903-w 
_citation.pdbx_database_id_PubMed   39952931 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Lee, Y.'          1  0000-0002-1507-805X 
primary 'Jin, C.'          2  ?                   
primary 'Ohgaki, R.'       3  0000-0002-6894-7239 
primary 'Xu, M.'           4  ?                   
primary 'Ogasawara, S.'    5  0000-0001-6908-9953 
primary 'Warshamanage, R.' 6  ?                   
primary 'Yamashita, K.'    7  0000-0002-5442-7582 
primary 'Murshudov, G.'    8  ?                   
primary 'Nureki, O.'       9  0000-0003-1813-7008 
primary 'Murata, T.'       10 0000-0002-5748-4670 
primary 'Kanai, Y.'        11 0000-0001-8126-286X 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man '4F2 cell-surface antigen heavy chain'                                68069.625 1 ? ? ? ? 
2 polymer     man 'Large neutral amino acids transporter small subunit 1'               56043.746 1 ? ? ? ? 
3 polymer     nat 'Fab170 light chain'                                                  24355.986 1 ? ? ? ? 
4 polymer     nat 'Fab170 heavy chain'                                                  24981.906 1 ? ? ? ? 
5 non-polymer syn 2-acetamido-2-deoxy-beta-D-glucopyranose                              221.208   4 ? ? ? ? 
6 non-polymer syn '(1~{S},2~{R},4~{R})-2-azanylbicyclo[2.2.1]heptane-2-carboxylic acid' 155.194   1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Glycoprotein, 4F2hc,4F2 heavy chain antigen,Lymphocyte activation antigen 4F2 large subunit,Solute carrier family 3 member 2' 
2 
;4F2 light chain,4F2LC,CD98 light chain,Integral membrane protein E16,L-type amino acid transporter 1,hLAT1,Solute carrier family 7 member 5,y+ system cationic amino acid transporter
;
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;GSELQPPEASIAVVSIPRQLPGSHSEAGVQGLSAGDDSELGSHCVAQTGLELLASGDPLPSASQNAEMIETGSDCVTQAG
LQLLASSDPPALASKNAEVTGTMSQDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEKNGLVKIKVAEDEAEAAAAA
KFTGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAG
NLAGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWF
STQVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQILSLLESNKDLL
LTSSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAAL
PGQPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQ
NERFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPYAA
;
;GSELQPPEASIAVVSIPRQLPGSHSEAGVQGLSAGDDSELGSHCVAQTGLELLASGDPLPSASQNAEMIETGSDCVTQAG
LQLLASSDPPALASKNAEVTGTMSQDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEKNGLVKIKVAEDEAEAAAAA
KFTGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAG
NLAGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWF
STQVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQILSLLESNKDLL
LTSSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAAL
PGQPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQ
NERFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPYAA
;
A ? 
2 'polypeptide(L)' no no 
;MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAG
SPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPL
FPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV
GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHL
GVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFF
SFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN
KPKWLLQGIFSTTVLCQKLMQVVPQETDYKDDDDK
;
;MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAG
SPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPL
FPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV
GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHL
GVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFF
SFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN
KPKWLLQGIFSTTVLCQKLMQVVPQETDYKDDDDK
;
B ? 
3 'polypeptide(L)' no no 
;DIVLTQSPSSLAMSVGQKVTMNCKSSQSLLNNNNQKNYLAWYQQKPGQSPKLLVYFTSTRESGVPDRFIGSGSGTDFTLT
ISSVQAEDLALYYCQQHYTIPPTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSE
RQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC
;
;DIVLTQSPSSLAMSVGQKVTMNCKSSQSLLNNNNQKNYLAWYQQKPGQSPKLLVYFTSTRESGVPDRFIGSGSGTDFTLT
ISSVQAEDLALYYCQQHYTIPPTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSE
RQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC
;
L ? 
4 'polypeptide(L)' no no 
;EVQLQQSGAELVKPGASVNLSCKASGYTFTNYWMHWVRLRPGQGLEWIGEIDPSDSYSYYSQNFKGKATLTVDQSSNTAY
LQLTSLTSEDSAVYYCARGRQTYYPWFPYWGQGTLVTVSAAKTTPPSDYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVT
WNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRDCGCKPCICT
;
;EVQLQQSGAELVKPGASVNLSCKASGYTFTNYWMHWVRLRPGQGLEWIGEIDPSDSYSYYSQNFKGKATLTVDQSSNTAY
LQLTSLTSEDSAVYYCARGRQTYYPWFPYWGQGTLVTVSAAKTTPPSDYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVT
WNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRDCGCKPCICT
;
H ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
5 2-acetamido-2-deoxy-beta-D-glucopyranose                              NAG 
6 '(1~{S},2~{R},4~{R})-2-azanylbicyclo[2.2.1]heptane-2-carboxylic acid' VU0 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   SER n 
1 3   GLU n 
1 4   LEU n 
1 5   GLN n 
1 6   PRO n 
1 7   PRO n 
1 8   GLU n 
1 9   ALA n 
1 10  SER n 
1 11  ILE n 
1 12  ALA n 
1 13  VAL n 
1 14  VAL n 
1 15  SER n 
1 16  ILE n 
1 17  PRO n 
1 18  ARG n 
1 19  GLN n 
1 20  LEU n 
1 21  PRO n 
1 22  GLY n 
1 23  SER n 
1 24  HIS n 
1 25  SER n 
1 26  GLU n 
1 27  ALA n 
1 28  GLY n 
1 29  VAL n 
1 30  GLN n 
1 31  GLY n 
1 32  LEU n 
1 33  SER n 
1 34  ALA n 
1 35  GLY n 
1 36  ASP n 
1 37  ASP n 
1 38  SER n 
1 39  GLU n 
1 40  LEU n 
1 41  GLY n 
1 42  SER n 
1 43  HIS n 
1 44  CYS n 
1 45  VAL n 
1 46  ALA n 
1 47  GLN n 
1 48  THR n 
1 49  GLY n 
1 50  LEU n 
1 51  GLU n 
1 52  LEU n 
1 53  LEU n 
1 54  ALA n 
1 55  SER n 
1 56  GLY n 
1 57  ASP n 
1 58  PRO n 
1 59  LEU n 
1 60  PRO n 
1 61  SER n 
1 62  ALA n 
1 63  SER n 
1 64  GLN n 
1 65  ASN n 
1 66  ALA n 
1 67  GLU n 
1 68  MET n 
1 69  ILE n 
1 70  GLU n 
1 71  THR n 
1 72  GLY n 
1 73  SER n 
1 74  ASP n 
1 75  CYS n 
1 76  VAL n 
1 77  THR n 
1 78  GLN n 
1 79  ALA n 
1 80  GLY n 
1 81  LEU n 
1 82  GLN n 
1 83  LEU n 
1 84  LEU n 
1 85  ALA n 
1 86  SER n 
1 87  SER n 
1 88  ASP n 
1 89  PRO n 
1 90  PRO n 
1 91  ALA n 
1 92  LEU n 
1 93  ALA n 
1 94  SER n 
1 95  LYS n 
1 96  ASN n 
1 97  ALA n 
1 98  GLU n 
1 99  VAL n 
1 100 THR n 
1 101 GLY n 
1 102 THR n 
1 103 MET n 
1 104 SER n 
1 105 GLN n 
1 106 ASP n 
1 107 THR n 
1 108 GLU n 
1 109 VAL n 
1 110 ASP n 
1 111 MET n 
1 112 LYS n 
1 113 GLU n 
1 114 VAL n 
1 115 GLU n 
1 116 LEU n 
1 117 ASN n 
1 118 GLU n 
1 119 LEU n 
1 120 GLU n 
1 121 PRO n 
1 122 GLU n 
1 123 LYS n 
1 124 GLN n 
1 125 PRO n 
1 126 MET n 
1 127 ASN n 
1 128 ALA n 
1 129 ALA n 
1 130 SER n 
1 131 GLY n 
1 132 ALA n 
1 133 ALA n 
1 134 MET n 
1 135 SER n 
1 136 LEU n 
1 137 ALA n 
1 138 GLY n 
1 139 ALA n 
1 140 GLU n 
1 141 LYS n 
1 142 ASN n 
1 143 GLY n 
1 144 LEU n 
1 145 VAL n 
1 146 LYS n 
1 147 ILE n 
1 148 LYS n 
1 149 VAL n 
1 150 ALA n 
1 151 GLU n 
1 152 ASP n 
1 153 GLU n 
1 154 ALA n 
1 155 GLU n 
1 156 ALA n 
1 157 ALA n 
1 158 ALA n 
1 159 ALA n 
1 160 ALA n 
1 161 LYS n 
1 162 PHE n 
1 163 THR n 
1 164 GLY n 
1 165 LEU n 
1 166 SER n 
1 167 LYS n 
1 168 GLU n 
1 169 GLU n 
1 170 LEU n 
1 171 LEU n 
1 172 LYS n 
1 173 VAL n 
1 174 ALA n 
1 175 GLY n 
1 176 SER n 
1 177 PRO n 
1 178 GLY n 
1 179 TRP n 
1 180 VAL n 
1 181 ARG n 
1 182 THR n 
1 183 ARG n 
1 184 TRP n 
1 185 ALA n 
1 186 LEU n 
1 187 LEU n 
1 188 LEU n 
1 189 LEU n 
1 190 PHE n 
1 191 TRP n 
1 192 LEU n 
1 193 GLY n 
1 194 TRP n 
1 195 LEU n 
1 196 GLY n 
1 197 MET n 
1 198 LEU n 
1 199 ALA n 
1 200 GLY n 
1 201 ALA n 
1 202 VAL n 
1 203 VAL n 
1 204 ILE n 
1 205 ILE n 
1 206 VAL n 
1 207 ARG n 
1 208 ALA n 
1 209 PRO n 
1 210 ARG n 
1 211 CYS n 
1 212 ARG n 
1 213 GLU n 
1 214 LEU n 
1 215 PRO n 
1 216 ALA n 
1 217 GLN n 
1 218 LYS n 
1 219 TRP n 
1 220 TRP n 
1 221 HIS n 
1 222 THR n 
1 223 GLY n 
1 224 ALA n 
1 225 LEU n 
1 226 TYR n 
1 227 ARG n 
1 228 ILE n 
1 229 GLY n 
1 230 ASP n 
1 231 LEU n 
1 232 GLN n 
1 233 ALA n 
1 234 PHE n 
1 235 GLN n 
1 236 GLY n 
1 237 HIS n 
1 238 GLY n 
1 239 ALA n 
1 240 GLY n 
1 241 ASN n 
1 242 LEU n 
1 243 ALA n 
1 244 GLY n 
1 245 LEU n 
1 246 LYS n 
1 247 GLY n 
1 248 ARG n 
1 249 LEU n 
1 250 ASP n 
1 251 TYR n 
1 252 LEU n 
1 253 SER n 
1 254 SER n 
1 255 LEU n 
1 256 LYS n 
1 257 VAL n 
1 258 LYS n 
1 259 GLY n 
1 260 LEU n 
1 261 VAL n 
1 262 LEU n 
1 263 GLY n 
1 264 PRO n 
1 265 ILE n 
1 266 HIS n 
1 267 LYS n 
1 268 ASN n 
1 269 GLN n 
1 270 LYS n 
1 271 ASP n 
1 272 ASP n 
1 273 VAL n 
1 274 ALA n 
1 275 GLN n 
1 276 THR n 
1 277 ASP n 
1 278 LEU n 
1 279 LEU n 
1 280 GLN n 
1 281 ILE n 
1 282 ASP n 
1 283 PRO n 
1 284 ASN n 
1 285 PHE n 
1 286 GLY n 
1 287 SER n 
1 288 LYS n 
1 289 GLU n 
1 290 ASP n 
1 291 PHE n 
1 292 ASP n 
1 293 SER n 
1 294 LEU n 
1 295 LEU n 
1 296 GLN n 
1 297 SER n 
1 298 ALA n 
1 299 LYS n 
1 300 LYS n 
1 301 LYS n 
1 302 SER n 
1 303 ILE n 
1 304 ARG n 
1 305 VAL n 
1 306 ILE n 
1 307 LEU n 
1 308 ASP n 
1 309 LEU n 
1 310 THR n 
1 311 PRO n 
1 312 ASN n 
1 313 TYR n 
1 314 ARG n 
1 315 GLY n 
1 316 GLU n 
1 317 ASN n 
1 318 SER n 
1 319 TRP n 
1 320 PHE n 
1 321 SER n 
1 322 THR n 
1 323 GLN n 
1 324 VAL n 
1 325 ASP n 
1 326 THR n 
1 327 VAL n 
1 328 ALA n 
1 329 THR n 
1 330 LYS n 
1 331 VAL n 
1 332 LYS n 
1 333 ASP n 
1 334 ALA n 
1 335 LEU n 
1 336 GLU n 
1 337 PHE n 
1 338 TRP n 
1 339 LEU n 
1 340 GLN n 
1 341 ALA n 
1 342 GLY n 
1 343 VAL n 
1 344 ASP n 
1 345 GLY n 
1 346 PHE n 
1 347 GLN n 
1 348 VAL n 
1 349 ARG n 
1 350 ASP n 
1 351 ILE n 
1 352 GLU n 
1 353 ASN n 
1 354 LEU n 
1 355 LYS n 
1 356 ASP n 
1 357 ALA n 
1 358 SER n 
1 359 SER n 
1 360 PHE n 
1 361 LEU n 
1 362 ALA n 
1 363 GLU n 
1 364 TRP n 
1 365 GLN n 
1 366 ASN n 
1 367 ILE n 
1 368 THR n 
1 369 LYS n 
1 370 GLY n 
1 371 PHE n 
1 372 SER n 
1 373 GLU n 
1 374 ASP n 
1 375 ARG n 
1 376 LEU n 
1 377 LEU n 
1 378 ILE n 
1 379 ALA n 
1 380 GLY n 
1 381 THR n 
1 382 ASN n 
1 383 SER n 
1 384 SER n 
1 385 ASP n 
1 386 LEU n 
1 387 GLN n 
1 388 GLN n 
1 389 ILE n 
1 390 LEU n 
1 391 SER n 
1 392 LEU n 
1 393 LEU n 
1 394 GLU n 
1 395 SER n 
1 396 ASN n 
1 397 LYS n 
1 398 ASP n 
1 399 LEU n 
1 400 LEU n 
1 401 LEU n 
1 402 THR n 
1 403 SER n 
1 404 SER n 
1 405 TYR n 
1 406 LEU n 
1 407 SER n 
1 408 ASP n 
1 409 SER n 
1 410 GLY n 
1 411 SER n 
1 412 THR n 
1 413 GLY n 
1 414 GLU n 
1 415 HIS n 
1 416 THR n 
1 417 LYS n 
1 418 SER n 
1 419 LEU n 
1 420 VAL n 
1 421 THR n 
1 422 GLN n 
1 423 TYR n 
1 424 LEU n 
1 425 ASN n 
1 426 ALA n 
1 427 THR n 
1 428 GLY n 
1 429 ASN n 
1 430 ARG n 
1 431 TRP n 
1 432 CYS n 
1 433 SER n 
1 434 TRP n 
1 435 SER n 
1 436 LEU n 
1 437 SER n 
1 438 GLN n 
1 439 ALA n 
1 440 ARG n 
1 441 LEU n 
1 442 LEU n 
1 443 THR n 
1 444 SER n 
1 445 PHE n 
1 446 LEU n 
1 447 PRO n 
1 448 ALA n 
1 449 GLN n 
1 450 LEU n 
1 451 LEU n 
1 452 ARG n 
1 453 LEU n 
1 454 TYR n 
1 455 GLN n 
1 456 LEU n 
1 457 MET n 
1 458 LEU n 
1 459 PHE n 
1 460 THR n 
1 461 LEU n 
1 462 PRO n 
1 463 GLY n 
1 464 THR n 
1 465 PRO n 
1 466 VAL n 
1 467 PHE n 
1 468 SER n 
1 469 TYR n 
1 470 GLY n 
1 471 ASP n 
1 472 GLU n 
1 473 ILE n 
1 474 GLY n 
1 475 LEU n 
1 476 ASP n 
1 477 ALA n 
1 478 ALA n 
1 479 ALA n 
1 480 LEU n 
1 481 PRO n 
1 482 GLY n 
1 483 GLN n 
1 484 PRO n 
1 485 MET n 
1 486 GLU n 
1 487 ALA n 
1 488 PRO n 
1 489 VAL n 
1 490 MET n 
1 491 LEU n 
1 492 TRP n 
1 493 ASP n 
1 494 GLU n 
1 495 SER n 
1 496 SER n 
1 497 PHE n 
1 498 PRO n 
1 499 ASP n 
1 500 ILE n 
1 501 PRO n 
1 502 GLY n 
1 503 ALA n 
1 504 VAL n 
1 505 SER n 
1 506 ALA n 
1 507 ASN n 
1 508 MET n 
1 509 THR n 
1 510 VAL n 
1 511 LYS n 
1 512 GLY n 
1 513 GLN n 
1 514 SER n 
1 515 GLU n 
1 516 ASP n 
1 517 PRO n 
1 518 GLY n 
1 519 SER n 
1 520 LEU n 
1 521 LEU n 
1 522 SER n 
1 523 LEU n 
1 524 PHE n 
1 525 ARG n 
1 526 ARG n 
1 527 LEU n 
1 528 SER n 
1 529 ASP n 
1 530 GLN n 
1 531 ARG n 
1 532 SER n 
1 533 LYS n 
1 534 GLU n 
1 535 ARG n 
1 536 SER n 
1 537 LEU n 
1 538 LEU n 
1 539 HIS n 
1 540 GLY n 
1 541 ASP n 
1 542 PHE n 
1 543 HIS n 
1 544 ALA n 
1 545 PHE n 
1 546 SER n 
1 547 ALA n 
1 548 GLY n 
1 549 PRO n 
1 550 GLY n 
1 551 LEU n 
1 552 PHE n 
1 553 SER n 
1 554 TYR n 
1 555 ILE n 
1 556 ARG n 
1 557 HIS n 
1 558 TRP n 
1 559 ASP n 
1 560 GLN n 
1 561 ASN n 
1 562 GLU n 
1 563 ARG n 
1 564 PHE n 
1 565 LEU n 
1 566 VAL n 
1 567 VAL n 
1 568 LEU n 
1 569 ASN n 
1 570 PHE n 
1 571 GLY n 
1 572 ASP n 
1 573 VAL n 
1 574 GLY n 
1 575 LEU n 
1 576 SER n 
1 577 ALA n 
1 578 GLY n 
1 579 LEU n 
1 580 GLN n 
1 581 ALA n 
1 582 SER n 
1 583 ASP n 
1 584 LEU n 
1 585 PRO n 
1 586 ALA n 
1 587 SER n 
1 588 ALA n 
1 589 SER n 
1 590 LEU n 
1 591 PRO n 
1 592 ALA n 
1 593 LYS n 
1 594 ALA n 
1 595 ASP n 
1 596 LEU n 
1 597 LEU n 
1 598 LEU n 
1 599 SER n 
1 600 THR n 
1 601 GLN n 
1 602 PRO n 
1 603 GLY n 
1 604 ARG n 
1 605 GLU n 
1 606 GLU n 
1 607 GLY n 
1 608 SER n 
1 609 PRO n 
1 610 LEU n 
1 611 GLU n 
1 612 LEU n 
1 613 GLU n 
1 614 ARG n 
1 615 LEU n 
1 616 LYS n 
1 617 LEU n 
1 618 GLU n 
1 619 PRO n 
1 620 HIS n 
1 621 GLU n 
1 622 GLY n 
1 623 LEU n 
1 624 LEU n 
1 625 LEU n 
1 626 ARG n 
1 627 PHE n 
1 628 PRO n 
1 629 TYR n 
1 630 ALA n 
1 631 ALA n 
2 1   MET n 
2 2   ALA n 
2 3   GLY n 
2 4   ALA n 
2 5   GLY n 
2 6   PRO n 
2 7   LYS n 
2 8   ARG n 
2 9   ARG n 
2 10  ALA n 
2 11  LEU n 
2 12  ALA n 
2 13  ALA n 
2 14  PRO n 
2 15  ALA n 
2 16  ALA n 
2 17  GLU n 
2 18  GLU n 
2 19  LYS n 
2 20  GLU n 
2 21  GLU n 
2 22  ALA n 
2 23  ARG n 
2 24  GLU n 
2 25  LYS n 
2 26  MET n 
2 27  LEU n 
2 28  ALA n 
2 29  ALA n 
2 30  LYS n 
2 31  SER n 
2 32  ALA n 
2 33  ASP n 
2 34  GLY n 
2 35  SER n 
2 36  ALA n 
2 37  PRO n 
2 38  ALA n 
2 39  GLY n 
2 40  GLU n 
2 41  GLY n 
2 42  GLU n 
2 43  GLY n 
2 44  VAL n 
2 45  THR n 
2 46  LEU n 
2 47  GLN n 
2 48  ARG n 
2 49  ASN n 
2 50  ILE n 
2 51  THR n 
2 52  LEU n 
2 53  LEU n 
2 54  ASN n 
2 55  GLY n 
2 56  VAL n 
2 57  ALA n 
2 58  ILE n 
2 59  ILE n 
2 60  VAL n 
2 61  GLY n 
2 62  THR n 
2 63  ILE n 
2 64  ILE n 
2 65  GLY n 
2 66  SER n 
2 67  GLY n 
2 68  ILE n 
2 69  PHE n 
2 70  VAL n 
2 71  THR n 
2 72  PRO n 
2 73  THR n 
2 74  GLY n 
2 75  VAL n 
2 76  LEU n 
2 77  LYS n 
2 78  GLU n 
2 79  ALA n 
2 80  GLY n 
2 81  SER n 
2 82  PRO n 
2 83  GLY n 
2 84  LEU n 
2 85  ALA n 
2 86  LEU n 
2 87  VAL n 
2 88  VAL n 
2 89  TRP n 
2 90  ALA n 
2 91  ALA n 
2 92  CYS n 
2 93  GLY n 
2 94  VAL n 
2 95  PHE n 
2 96  SER n 
2 97  ILE n 
2 98  VAL n 
2 99  GLY n 
2 100 ALA n 
2 101 LEU n 
2 102 CYS n 
2 103 TYR n 
2 104 ALA n 
2 105 GLU n 
2 106 LEU n 
2 107 GLY n 
2 108 THR n 
2 109 THR n 
2 110 ILE n 
2 111 SER n 
2 112 LYS n 
2 113 SER n 
2 114 GLY n 
2 115 GLY n 
2 116 ASP n 
2 117 TYR n 
2 118 ALA n 
2 119 TYR n 
2 120 MET n 
2 121 LEU n 
2 122 GLU n 
2 123 VAL n 
2 124 TYR n 
2 125 GLY n 
2 126 SER n 
2 127 LEU n 
2 128 PRO n 
2 129 ALA n 
2 130 PHE n 
2 131 LEU n 
2 132 LYS n 
2 133 LEU n 
2 134 TRP n 
2 135 ILE n 
2 136 GLU n 
2 137 LEU n 
2 138 LEU n 
2 139 ILE n 
2 140 ILE n 
2 141 ARG n 
2 142 PRO n 
2 143 SER n 
2 144 SER n 
2 145 GLN n 
2 146 TYR n 
2 147 ILE n 
2 148 VAL n 
2 149 ALA n 
2 150 LEU n 
2 151 VAL n 
2 152 PHE n 
2 153 ALA n 
2 154 THR n 
2 155 TYR n 
2 156 LEU n 
2 157 LEU n 
2 158 LYS n 
2 159 PRO n 
2 160 LEU n 
2 161 PHE n 
2 162 PRO n 
2 163 THR n 
2 164 CYS n 
2 165 PRO n 
2 166 VAL n 
2 167 PRO n 
2 168 GLU n 
2 169 GLU n 
2 170 ALA n 
2 171 ALA n 
2 172 LYS n 
2 173 LEU n 
2 174 VAL n 
2 175 ALA n 
2 176 CYS n 
2 177 LEU n 
2 178 CYS n 
2 179 VAL n 
2 180 LEU n 
2 181 LEU n 
2 182 LEU n 
2 183 THR n 
2 184 ALA n 
2 185 VAL n 
2 186 ASN n 
2 187 CYS n 
2 188 TYR n 
2 189 SER n 
2 190 VAL n 
2 191 LYS n 
2 192 ALA n 
2 193 ALA n 
2 194 THR n 
2 195 ARG n 
2 196 VAL n 
2 197 GLN n 
2 198 ASP n 
2 199 ALA n 
2 200 PHE n 
2 201 ALA n 
2 202 ALA n 
2 203 ALA n 
2 204 LYS n 
2 205 LEU n 
2 206 LEU n 
2 207 ALA n 
2 208 LEU n 
2 209 ALA n 
2 210 LEU n 
2 211 ILE n 
2 212 ILE n 
2 213 LEU n 
2 214 LEU n 
2 215 GLY n 
2 216 PHE n 
2 217 VAL n 
2 218 GLN n 
2 219 ILE n 
2 220 GLY n 
2 221 LYS n 
2 222 GLY n 
2 223 ASP n 
2 224 VAL n 
2 225 SER n 
2 226 ASN n 
2 227 LEU n 
2 228 ASP n 
2 229 PRO n 
2 230 ASN n 
2 231 PHE n 
2 232 SER n 
2 233 PHE n 
2 234 GLU n 
2 235 GLY n 
2 236 THR n 
2 237 LYS n 
2 238 LEU n 
2 239 ASP n 
2 240 VAL n 
2 241 GLY n 
2 242 ASN n 
2 243 ILE n 
2 244 VAL n 
2 245 LEU n 
2 246 ALA n 
2 247 LEU n 
2 248 TYR n 
2 249 SER n 
2 250 GLY n 
2 251 LEU n 
2 252 PHE n 
2 253 ALA n 
2 254 TYR n 
2 255 GLY n 
2 256 GLY n 
2 257 TRP n 
2 258 ASN n 
2 259 TYR n 
2 260 LEU n 
2 261 ASN n 
2 262 PHE n 
2 263 VAL n 
2 264 THR n 
2 265 GLU n 
2 266 GLU n 
2 267 MET n 
2 268 ILE n 
2 269 ASN n 
2 270 PRO n 
2 271 TYR n 
2 272 ARG n 
2 273 ASN n 
2 274 LEU n 
2 275 PRO n 
2 276 LEU n 
2 277 ALA n 
2 278 ILE n 
2 279 ILE n 
2 280 ILE n 
2 281 SER n 
2 282 LEU n 
2 283 PRO n 
2 284 ILE n 
2 285 VAL n 
2 286 THR n 
2 287 LEU n 
2 288 VAL n 
2 289 TYR n 
2 290 VAL n 
2 291 LEU n 
2 292 THR n 
2 293 ASN n 
2 294 LEU n 
2 295 ALA n 
2 296 TYR n 
2 297 PHE n 
2 298 THR n 
2 299 THR n 
2 300 LEU n 
2 301 SER n 
2 302 THR n 
2 303 GLU n 
2 304 GLN n 
2 305 MET n 
2 306 LEU n 
2 307 SER n 
2 308 SER n 
2 309 GLU n 
2 310 ALA n 
2 311 VAL n 
2 312 ALA n 
2 313 VAL n 
2 314 ASP n 
2 315 PHE n 
2 316 GLY n 
2 317 ASN n 
2 318 TYR n 
2 319 HIS n 
2 320 LEU n 
2 321 GLY n 
2 322 VAL n 
2 323 MET n 
2 324 SER n 
2 325 TRP n 
2 326 ILE n 
2 327 ILE n 
2 328 PRO n 
2 329 VAL n 
2 330 PHE n 
2 331 VAL n 
2 332 GLY n 
2 333 LEU n 
2 334 SER n 
2 335 CYS n 
2 336 PHE n 
2 337 GLY n 
2 338 SER n 
2 339 VAL n 
2 340 ASN n 
2 341 GLY n 
2 342 SER n 
2 343 LEU n 
2 344 PHE n 
2 345 THR n 
2 346 SER n 
2 347 SER n 
2 348 ARG n 
2 349 LEU n 
2 350 PHE n 
2 351 PHE n 
2 352 VAL n 
2 353 GLY n 
2 354 SER n 
2 355 ARG n 
2 356 GLU n 
2 357 GLY n 
2 358 HIS n 
2 359 LEU n 
2 360 PRO n 
2 361 SER n 
2 362 ILE n 
2 363 LEU n 
2 364 SER n 
2 365 MET n 
2 366 ILE n 
2 367 HIS n 
2 368 PRO n 
2 369 GLN n 
2 370 LEU n 
2 371 LEU n 
2 372 THR n 
2 373 PRO n 
2 374 VAL n 
2 375 PRO n 
2 376 SER n 
2 377 LEU n 
2 378 VAL n 
2 379 PHE n 
2 380 THR n 
2 381 CYS n 
2 382 VAL n 
2 383 MET n 
2 384 THR n 
2 385 LEU n 
2 386 LEU n 
2 387 TYR n 
2 388 ALA n 
2 389 PHE n 
2 390 SER n 
2 391 LYS n 
2 392 ASP n 
2 393 ILE n 
2 394 PHE n 
2 395 SER n 
2 396 VAL n 
2 397 ILE n 
2 398 ASN n 
2 399 PHE n 
2 400 PHE n 
2 401 SER n 
2 402 PHE n 
2 403 PHE n 
2 404 ASN n 
2 405 TRP n 
2 406 LEU n 
2 407 CYS n 
2 408 VAL n 
2 409 ALA n 
2 410 LEU n 
2 411 ALA n 
2 412 ILE n 
2 413 ILE n 
2 414 GLY n 
2 415 MET n 
2 416 ILE n 
2 417 TRP n 
2 418 LEU n 
2 419 ARG n 
2 420 HIS n 
2 421 ARG n 
2 422 LYS n 
2 423 PRO n 
2 424 GLU n 
2 425 LEU n 
2 426 GLU n 
2 427 ARG n 
2 428 PRO n 
2 429 ILE n 
2 430 LYS n 
2 431 VAL n 
2 432 ASN n 
2 433 LEU n 
2 434 ALA n 
2 435 LEU n 
2 436 PRO n 
2 437 VAL n 
2 438 PHE n 
2 439 PHE n 
2 440 ILE n 
2 441 LEU n 
2 442 ALA n 
2 443 CYS n 
2 444 LEU n 
2 445 PHE n 
2 446 LEU n 
2 447 ILE n 
2 448 ALA n 
2 449 VAL n 
2 450 SER n 
2 451 PHE n 
2 452 TRP n 
2 453 LYS n 
2 454 THR n 
2 455 PRO n 
2 456 VAL n 
2 457 GLU n 
2 458 CYS n 
2 459 GLY n 
2 460 ILE n 
2 461 GLY n 
2 462 PHE n 
2 463 THR n 
2 464 ILE n 
2 465 ILE n 
2 466 LEU n 
2 467 SER n 
2 468 GLY n 
2 469 LEU n 
2 470 PRO n 
2 471 VAL n 
2 472 TYR n 
2 473 PHE n 
2 474 PHE n 
2 475 GLY n 
2 476 VAL n 
2 477 TRP n 
2 478 TRP n 
2 479 LYS n 
2 480 ASN n 
2 481 LYS n 
2 482 PRO n 
2 483 LYS n 
2 484 TRP n 
2 485 LEU n 
2 486 LEU n 
2 487 GLN n 
2 488 GLY n 
2 489 ILE n 
2 490 PHE n 
2 491 SER n 
2 492 THR n 
2 493 THR n 
2 494 VAL n 
2 495 LEU n 
2 496 CYS n 
2 497 GLN n 
2 498 LYS n 
2 499 LEU n 
2 500 MET n 
2 501 GLN n 
2 502 VAL n 
2 503 VAL n 
2 504 PRO n 
2 505 GLN n 
2 506 GLU n 
2 507 THR n 
2 508 ASP n 
2 509 TYR n 
2 510 LYS n 
2 511 ASP n 
2 512 ASP n 
2 513 ASP n 
2 514 ASP n 
2 515 LYS n 
3 1   ASP n 
3 2   ILE n 
3 3   VAL n 
3 4   LEU n 
3 5   THR n 
3 6   GLN n 
3 7   SER n 
3 8   PRO n 
3 9   SER n 
3 10  SER n 
3 11  LEU n 
3 12  ALA n 
3 13  MET n 
3 14  SER n 
3 15  VAL n 
3 16  GLY n 
3 17  GLN n 
3 18  LYS n 
3 19  VAL n 
3 20  THR n 
3 21  MET n 
3 22  ASN n 
3 23  CYS n 
3 24  LYS n 
3 25  SER n 
3 26  SER n 
3 27  GLN n 
3 28  SER n 
3 29  LEU n 
3 30  LEU n 
3 31  ASN n 
3 32  ASN n 
3 33  ASN n 
3 34  ASN n 
3 35  GLN n 
3 36  LYS n 
3 37  ASN n 
3 38  TYR n 
3 39  LEU n 
3 40  ALA n 
3 41  TRP n 
3 42  TYR n 
3 43  GLN n 
3 44  GLN n 
3 45  LYS n 
3 46  PRO n 
3 47  GLY n 
3 48  GLN n 
3 49  SER n 
3 50  PRO n 
3 51  LYS n 
3 52  LEU n 
3 53  LEU n 
3 54  VAL n 
3 55  TYR n 
3 56  PHE n 
3 57  THR n 
3 58  SER n 
3 59  THR n 
3 60  ARG n 
3 61  GLU n 
3 62  SER n 
3 63  GLY n 
3 64  VAL n 
3 65  PRO n 
3 66  ASP n 
3 67  ARG n 
3 68  PHE n 
3 69  ILE n 
3 70  GLY n 
3 71  SER n 
3 72  GLY n 
3 73  SER n 
3 74  GLY n 
3 75  THR n 
3 76  ASP n 
3 77  PHE n 
3 78  THR n 
3 79  LEU n 
3 80  THR n 
3 81  ILE n 
3 82  SER n 
3 83  SER n 
3 84  VAL n 
3 85  GLN n 
3 86  ALA n 
3 87  GLU n 
3 88  ASP n 
3 89  LEU n 
3 90  ALA n 
3 91  LEU n 
3 92  TYR n 
3 93  TYR n 
3 94  CYS n 
3 95  GLN n 
3 96  GLN n 
3 97  HIS n 
3 98  TYR n 
3 99  THR n 
3 100 ILE n 
3 101 PRO n 
3 102 PRO n 
3 103 THR n 
3 104 PHE n 
3 105 GLY n 
3 106 GLY n 
3 107 GLY n 
3 108 THR n 
3 109 LYS n 
3 110 LEU n 
3 111 GLU n 
3 112 ILE n 
3 113 LYS n 
3 114 ARG n 
3 115 ALA n 
3 116 ASP n 
3 117 ALA n 
3 118 ALA n 
3 119 PRO n 
3 120 THR n 
3 121 VAL n 
3 122 SER n 
3 123 ILE n 
3 124 PHE n 
3 125 PRO n 
3 126 PRO n 
3 127 SER n 
3 128 SER n 
3 129 GLU n 
3 130 GLN n 
3 131 LEU n 
3 132 THR n 
3 133 SER n 
3 134 GLY n 
3 135 GLY n 
3 136 ALA n 
3 137 SER n 
3 138 VAL n 
3 139 VAL n 
3 140 CYS n 
3 141 PHE n 
3 142 LEU n 
3 143 ASN n 
3 144 ASN n 
3 145 PHE n 
3 146 TYR n 
3 147 PRO n 
3 148 LYS n 
3 149 ASP n 
3 150 ILE n 
3 151 ASN n 
3 152 VAL n 
3 153 LYS n 
3 154 TRP n 
3 155 LYS n 
3 156 ILE n 
3 157 ASP n 
3 158 GLY n 
3 159 SER n 
3 160 GLU n 
3 161 ARG n 
3 162 GLN n 
3 163 ASN n 
3 164 GLY n 
3 165 VAL n 
3 166 LEU n 
3 167 ASN n 
3 168 SER n 
3 169 TRP n 
3 170 THR n 
3 171 ASP n 
3 172 GLN n 
3 173 ASP n 
3 174 SER n 
3 175 LYS n 
3 176 ASP n 
3 177 SER n 
3 178 THR n 
3 179 TYR n 
3 180 SER n 
3 181 MET n 
3 182 SER n 
3 183 SER n 
3 184 THR n 
3 185 LEU n 
3 186 THR n 
3 187 LEU n 
3 188 THR n 
3 189 LYS n 
3 190 ASP n 
3 191 GLU n 
3 192 TYR n 
3 193 GLU n 
3 194 ARG n 
3 195 HIS n 
3 196 ASN n 
3 197 SER n 
3 198 TYR n 
3 199 THR n 
3 200 CYS n 
3 201 GLU n 
3 202 ALA n 
3 203 THR n 
3 204 HIS n 
3 205 LYS n 
3 206 THR n 
3 207 SER n 
3 208 THR n 
3 209 SER n 
3 210 PRO n 
3 211 ILE n 
3 212 VAL n 
3 213 LYS n 
3 214 SER n 
3 215 PHE n 
3 216 ASN n 
3 217 ARG n 
3 218 ASN n 
3 219 GLU n 
3 220 CYS n 
4 1   GLU n 
4 2   VAL n 
4 3   GLN n 
4 4   LEU n 
4 5   GLN n 
4 6   GLN n 
4 7   SER n 
4 8   GLY n 
4 9   ALA n 
4 10  GLU n 
4 11  LEU n 
4 12  VAL n 
4 13  LYS n 
4 14  PRO n 
4 15  GLY n 
4 16  ALA n 
4 17  SER n 
4 18  VAL n 
4 19  ASN n 
4 20  LEU n 
4 21  SER n 
4 22  CYS n 
4 23  LYS n 
4 24  ALA n 
4 25  SER n 
4 26  GLY n 
4 27  TYR n 
4 28  THR n 
4 29  PHE n 
4 30  THR n 
4 31  ASN n 
4 32  TYR n 
4 33  TRP n 
4 34  MET n 
4 35  HIS n 
4 36  TRP n 
4 37  VAL n 
4 38  ARG n 
4 39  LEU n 
4 40  ARG n 
4 41  PRO n 
4 42  GLY n 
4 43  GLN n 
4 44  GLY n 
4 45  LEU n 
4 46  GLU n 
4 47  TRP n 
4 48  ILE n 
4 49  GLY n 
4 50  GLU n 
4 51  ILE n 
4 52  ASP n 
4 53  PRO n 
4 54  SER n 
4 55  ASP n 
4 56  SER n 
4 57  TYR n 
4 58  SER n 
4 59  TYR n 
4 60  TYR n 
4 61  SER n 
4 62  GLN n 
4 63  ASN n 
4 64  PHE n 
4 65  LYS n 
4 66  GLY n 
4 67  LYS n 
4 68  ALA n 
4 69  THR n 
4 70  LEU n 
4 71  THR n 
4 72  VAL n 
4 73  ASP n 
4 74  GLN n 
4 75  SER n 
4 76  SER n 
4 77  ASN n 
4 78  THR n 
4 79  ALA n 
4 80  TYR n 
4 81  LEU n 
4 82  GLN n 
4 83  LEU n 
4 84  THR n 
4 85  SER n 
4 86  LEU n 
4 87  THR n 
4 88  SER n 
4 89  GLU n 
4 90  ASP n 
4 91  SER n 
4 92  ALA n 
4 93  VAL n 
4 94  TYR n 
4 95  TYR n 
4 96  CYS n 
4 97  ALA n 
4 98  ARG n 
4 99  GLY n 
4 100 ARG n 
4 101 GLN n 
4 102 THR n 
4 103 TYR n 
4 104 TYR n 
4 105 PRO n 
4 106 TRP n 
4 107 PHE n 
4 108 PRO n 
4 109 TYR n 
4 110 TRP n 
4 111 GLY n 
4 112 GLN n 
4 113 GLY n 
4 114 THR n 
4 115 LEU n 
4 116 VAL n 
4 117 THR n 
4 118 VAL n 
4 119 SER n 
4 120 ALA n 
4 121 ALA n 
4 122 LYS n 
4 123 THR n 
4 124 THR n 
4 125 PRO n 
4 126 PRO n 
4 127 SER n 
4 128 ASP n 
4 129 TYR n 
4 130 PRO n 
4 131 LEU n 
4 132 ALA n 
4 133 PRO n 
4 134 GLY n 
4 135 SER n 
4 136 ALA n 
4 137 ALA n 
4 138 GLN n 
4 139 THR n 
4 140 ASN n 
4 141 SER n 
4 142 MET n 
4 143 VAL n 
4 144 THR n 
4 145 LEU n 
4 146 GLY n 
4 147 CYS n 
4 148 LEU n 
4 149 VAL n 
4 150 LYS n 
4 151 GLY n 
4 152 TYR n 
4 153 PHE n 
4 154 PRO n 
4 155 GLU n 
4 156 PRO n 
4 157 VAL n 
4 158 THR n 
4 159 VAL n 
4 160 THR n 
4 161 TRP n 
4 162 ASN n 
4 163 SER n 
4 164 GLY n 
4 165 SER n 
4 166 LEU n 
4 167 SER n 
4 168 SER n 
4 169 GLY n 
4 170 VAL n 
4 171 HIS n 
4 172 THR n 
4 173 PHE n 
4 174 PRO n 
4 175 ALA n 
4 176 VAL n 
4 177 LEU n 
4 178 GLN n 
4 179 SER n 
4 180 ASP n 
4 181 LEU n 
4 182 TYR n 
4 183 THR n 
4 184 LEU n 
4 185 SER n 
4 186 SER n 
4 187 SER n 
4 188 VAL n 
4 189 THR n 
4 190 VAL n 
4 191 PRO n 
4 192 SER n 
4 193 SER n 
4 194 THR n 
4 195 TRP n 
4 196 PRO n 
4 197 SER n 
4 198 GLU n 
4 199 THR n 
4 200 VAL n 
4 201 THR n 
4 202 CYS n 
4 203 ASN n 
4 204 VAL n 
4 205 ALA n 
4 206 HIS n 
4 207 PRO n 
4 208 ALA n 
4 209 SER n 
4 210 SER n 
4 211 THR n 
4 212 LYS n 
4 213 VAL n 
4 214 ASP n 
4 215 LYS n 
4 216 LYS n 
4 217 ILE n 
4 218 VAL n 
4 219 PRO n 
4 220 ARG n 
4 221 ASP n 
4 222 CYS n 
4 223 GLY n 
4 224 CYS n 
4 225 LYS n 
4 226 PRO n 
4 227 CYS n 
4 228 ILE n 
4 229 CYS n 
4 230 THR n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 631 human ? 'SLC3A2, MDU1'                ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 515 human ? 'SLC7A5, CD98LC, LAT1, MPE16' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_entity_src_nat.entity_id 
_entity_src_nat.pdbx_src_id 
_entity_src_nat.pdbx_alt_source_flag 
_entity_src_nat.pdbx_beg_seq_num 
_entity_src_nat.pdbx_end_seq_num 
_entity_src_nat.common_name 
_entity_src_nat.pdbx_organism_scientific 
_entity_src_nat.pdbx_ncbi_taxonomy_id 
_entity_src_nat.genus 
_entity_src_nat.species 
_entity_src_nat.strain 
_entity_src_nat.tissue 
_entity_src_nat.tissue_fraction 
_entity_src_nat.pdbx_secretion 
_entity_src_nat.pdbx_fragment 
_entity_src_nat.pdbx_variant 
_entity_src_nat.pdbx_cell_line 
_entity_src_nat.pdbx_atcc 
_entity_src_nat.pdbx_cellular_location 
_entity_src_nat.pdbx_organ 
_entity_src_nat.pdbx_organelle 
_entity_src_nat.pdbx_cell 
_entity_src_nat.pdbx_plasmid_name 
_entity_src_nat.pdbx_plasmid_details 
_entity_src_nat.details 
3 1 sample 1 220 ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 1 230 ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE                                                               ? 'C3 H7 N O2'     89.093 
ARG 'L-peptide linking'          y ARGININE                                                              ? 'C6 H15 N4 O2 1' 
175.209 
ASN 'L-peptide linking'          y ASPARAGINE                                                            ? 'C4 H8 N2 O3'    
132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                                                       ? 'C4 H7 N O4'     
133.103 
CYS 'L-peptide linking'          y CYSTEINE                                                              ? 'C3 H7 N O2 S'   
121.158 
GLN 'L-peptide linking'          y GLUTAMINE                                                             ? 'C5 H10 N2 O3'   
146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                                                       ? 'C5 H9 N O4'     
147.129 
GLY 'peptide linking'            y GLYCINE                                                               ? 'C2 H5 N O2'     75.067 
HIS 'L-peptide linking'          y HISTIDINE                                                             ? 'C6 H10 N3 O2 1' 
156.162 
ILE 'L-peptide linking'          y ISOLEUCINE                                                            ? 'C6 H13 N O2'    
131.173 
LEU 'L-peptide linking'          y LEUCINE                                                               ? 'C6 H13 N O2'    
131.173 
LYS 'L-peptide linking'          y LYSINE                                                                ? 'C6 H15 N2 O2 1' 
147.195 
MET 'L-peptide linking'          y METHIONINE                                                            ? 'C5 H11 N O2 S'  
149.211 
NAG 'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose                              
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'          y PHENYLALANINE                                                         ? 'C9 H11 N O2'    
165.189 
PRO 'L-peptide linking'          y PROLINE                                                               ? 'C5 H9 N O2'     
115.130 
SER 'L-peptide linking'          y SERINE                                                                ? 'C3 H7 N O3'     
105.093 
THR 'L-peptide linking'          y THREONINE                                                             ? 'C4 H9 N O3'     
119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                                                            ? 'C11 H12 N2 O2'  
204.225 
TYR 'L-peptide linking'          y TYROSINE                                                              ? 'C9 H11 N O3'    
181.189 
VAL 'L-peptide linking'          y VALINE                                                                ? 'C5 H11 N O2'    
117.146 
VU0 non-polymer                  . '(1~{S},2~{R},4~{R})-2-azanylbicyclo[2.2.1]heptane-2-carboxylic acid' ? 'C8 H13 N O2'    
155.194 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   0   ?   ?   ?   A . n 
A 1 2   SER 2   1   ?   ?   ?   A . n 
A 1 3   GLU 3   2   ?   ?   ?   A . n 
A 1 4   LEU 4   3   ?   ?   ?   A . n 
A 1 5   GLN 5   4   ?   ?   ?   A . n 
A 1 6   PRO 6   5   ?   ?   ?   A . n 
A 1 7   PRO 7   6   ?   ?   ?   A . n 
A 1 8   GLU 8   7   ?   ?   ?   A . n 
A 1 9   ALA 9   8   ?   ?   ?   A . n 
A 1 10  SER 10  9   ?   ?   ?   A . n 
A 1 11  ILE 11  10  ?   ?   ?   A . n 
A 1 12  ALA 12  11  ?   ?   ?   A . n 
A 1 13  VAL 13  12  ?   ?   ?   A . n 
A 1 14  VAL 14  13  ?   ?   ?   A . n 
A 1 15  SER 15  14  ?   ?   ?   A . n 
A 1 16  ILE 16  15  ?   ?   ?   A . n 
A 1 17  PRO 17  16  ?   ?   ?   A . n 
A 1 18  ARG 18  17  ?   ?   ?   A . n 
A 1 19  GLN 19  18  ?   ?   ?   A . n 
A 1 20  LEU 20  19  ?   ?   ?   A . n 
A 1 21  PRO 21  20  ?   ?   ?   A . n 
A 1 22  GLY 22  21  ?   ?   ?   A . n 
A 1 23  SER 23  22  ?   ?   ?   A . n 
A 1 24  HIS 24  23  ?   ?   ?   A . n 
A 1 25  SER 25  24  ?   ?   ?   A . n 
A 1 26  GLU 26  25  ?   ?   ?   A . n 
A 1 27  ALA 27  26  ?   ?   ?   A . n 
A 1 28  GLY 28  27  ?   ?   ?   A . n 
A 1 29  VAL 29  28  ?   ?   ?   A . n 
A 1 30  GLN 30  29  ?   ?   ?   A . n 
A 1 31  GLY 31  30  ?   ?   ?   A . n 
A 1 32  LEU 32  31  ?   ?   ?   A . n 
A 1 33  SER 33  32  ?   ?   ?   A . n 
A 1 34  ALA 34  33  ?   ?   ?   A . n 
A 1 35  GLY 35  34  ?   ?   ?   A . n 
A 1 36  ASP 36  35  ?   ?   ?   A . n 
A 1 37  ASP 37  36  ?   ?   ?   A . n 
A 1 38  SER 38  37  ?   ?   ?   A . n 
A 1 39  GLU 39  38  ?   ?   ?   A . n 
A 1 40  LEU 40  39  ?   ?   ?   A . n 
A 1 41  GLY 41  40  ?   ?   ?   A . n 
A 1 42  SER 42  41  ?   ?   ?   A . n 
A 1 43  HIS 43  42  ?   ?   ?   A . n 
A 1 44  CYS 44  43  ?   ?   ?   A . n 
A 1 45  VAL 45  44  ?   ?   ?   A . n 
A 1 46  ALA 46  45  ?   ?   ?   A . n 
A 1 47  GLN 47  46  ?   ?   ?   A . n 
A 1 48  THR 48  47  ?   ?   ?   A . n 
A 1 49  GLY 49  48  ?   ?   ?   A . n 
A 1 50  LEU 50  49  ?   ?   ?   A . n 
A 1 51  GLU 51  50  ?   ?   ?   A . n 
A 1 52  LEU 52  51  ?   ?   ?   A . n 
A 1 53  LEU 53  52  ?   ?   ?   A . n 
A 1 54  ALA 54  53  ?   ?   ?   A . n 
A 1 55  SER 55  54  ?   ?   ?   A . n 
A 1 56  GLY 56  55  ?   ?   ?   A . n 
A 1 57  ASP 57  56  ?   ?   ?   A . n 
A 1 58  PRO 58  57  ?   ?   ?   A . n 
A 1 59  LEU 59  58  ?   ?   ?   A . n 
A 1 60  PRO 60  59  ?   ?   ?   A . n 
A 1 61  SER 61  60  ?   ?   ?   A . n 
A 1 62  ALA 62  61  ?   ?   ?   A . n 
A 1 63  SER 63  62  ?   ?   ?   A . n 
A 1 64  GLN 64  63  ?   ?   ?   A . n 
A 1 65  ASN 65  64  ?   ?   ?   A . n 
A 1 66  ALA 66  65  ?   ?   ?   A . n 
A 1 67  GLU 67  66  ?   ?   ?   A . n 
A 1 68  MET 68  67  ?   ?   ?   A . n 
A 1 69  ILE 69  68  ?   ?   ?   A . n 
A 1 70  GLU 70  69  ?   ?   ?   A . n 
A 1 71  THR 71  70  ?   ?   ?   A . n 
A 1 72  GLY 72  71  ?   ?   ?   A . n 
A 1 73  SER 73  72  ?   ?   ?   A . n 
A 1 74  ASP 74  73  ?   ?   ?   A . n 
A 1 75  CYS 75  74  ?   ?   ?   A . n 
A 1 76  VAL 76  75  ?   ?   ?   A . n 
A 1 77  THR 77  76  ?   ?   ?   A . n 
A 1 78  GLN 78  77  ?   ?   ?   A . n 
A 1 79  ALA 79  78  ?   ?   ?   A . n 
A 1 80  GLY 80  79  ?   ?   ?   A . n 
A 1 81  LEU 81  80  ?   ?   ?   A . n 
A 1 82  GLN 82  81  ?   ?   ?   A . n 
A 1 83  LEU 83  82  ?   ?   ?   A . n 
A 1 84  LEU 84  83  ?   ?   ?   A . n 
A 1 85  ALA 85  84  ?   ?   ?   A . n 
A 1 86  SER 86  85  ?   ?   ?   A . n 
A 1 87  SER 87  86  ?   ?   ?   A . n 
A 1 88  ASP 88  87  ?   ?   ?   A . n 
A 1 89  PRO 89  88  ?   ?   ?   A . n 
A 1 90  PRO 90  89  ?   ?   ?   A . n 
A 1 91  ALA 91  90  ?   ?   ?   A . n 
A 1 92  LEU 92  91  ?   ?   ?   A . n 
A 1 93  ALA 93  92  ?   ?   ?   A . n 
A 1 94  SER 94  93  ?   ?   ?   A . n 
A 1 95  LYS 95  94  ?   ?   ?   A . n 
A 1 96  ASN 96  95  ?   ?   ?   A . n 
A 1 97  ALA 97  96  ?   ?   ?   A . n 
A 1 98  GLU 98  97  ?   ?   ?   A . n 
A 1 99  VAL 99  98  ?   ?   ?   A . n 
A 1 100 THR 100 99  ?   ?   ?   A . n 
A 1 101 GLY 101 100 ?   ?   ?   A . n 
A 1 102 THR 102 101 ?   ?   ?   A . n 
A 1 103 MET 103 102 ?   ?   ?   A . n 
A 1 104 SER 104 103 ?   ?   ?   A . n 
A 1 105 GLN 105 104 ?   ?   ?   A . n 
A 1 106 ASP 106 105 ?   ?   ?   A . n 
A 1 107 THR 107 106 ?   ?   ?   A . n 
A 1 108 GLU 108 107 ?   ?   ?   A . n 
A 1 109 VAL 109 108 ?   ?   ?   A . n 
A 1 110 ASP 110 109 ?   ?   ?   A . n 
A 1 111 MET 111 110 ?   ?   ?   A . n 
A 1 112 LYS 112 111 ?   ?   ?   A . n 
A 1 113 GLU 113 112 ?   ?   ?   A . n 
A 1 114 VAL 114 113 ?   ?   ?   A . n 
A 1 115 GLU 115 114 ?   ?   ?   A . n 
A 1 116 LEU 116 115 ?   ?   ?   A . n 
A 1 117 ASN 117 116 ?   ?   ?   A . n 
A 1 118 GLU 118 117 ?   ?   ?   A . n 
A 1 119 LEU 119 118 ?   ?   ?   A . n 
A 1 120 GLU 120 119 ?   ?   ?   A . n 
A 1 121 PRO 121 120 ?   ?   ?   A . n 
A 1 122 GLU 122 121 ?   ?   ?   A . n 
A 1 123 LYS 123 122 ?   ?   ?   A . n 
A 1 124 GLN 124 123 ?   ?   ?   A . n 
A 1 125 PRO 125 124 ?   ?   ?   A . n 
A 1 126 MET 126 125 ?   ?   ?   A . n 
A 1 127 ASN 127 126 ?   ?   ?   A . n 
A 1 128 ALA 128 127 ?   ?   ?   A . n 
A 1 129 ALA 129 128 ?   ?   ?   A . n 
A 1 130 SER 130 129 ?   ?   ?   A . n 
A 1 131 GLY 131 130 ?   ?   ?   A . n 
A 1 132 ALA 132 131 ?   ?   ?   A . n 
A 1 133 ALA 133 132 ?   ?   ?   A . n 
A 1 134 MET 134 133 ?   ?   ?   A . n 
A 1 135 SER 135 134 ?   ?   ?   A . n 
A 1 136 LEU 136 135 ?   ?   ?   A . n 
A 1 137 ALA 137 136 ?   ?   ?   A . n 
A 1 138 GLY 138 137 ?   ?   ?   A . n 
A 1 139 ALA 139 138 ?   ?   ?   A . n 
A 1 140 GLU 140 139 ?   ?   ?   A . n 
A 1 141 LYS 141 140 ?   ?   ?   A . n 
A 1 142 ASN 142 141 ?   ?   ?   A . n 
A 1 143 GLY 143 142 ?   ?   ?   A . n 
A 1 144 LEU 144 143 ?   ?   ?   A . n 
A 1 145 VAL 145 144 ?   ?   ?   A . n 
A 1 146 LYS 146 145 ?   ?   ?   A . n 
A 1 147 ILE 147 146 ?   ?   ?   A . n 
A 1 148 LYS 148 147 ?   ?   ?   A . n 
A 1 149 VAL 149 148 ?   ?   ?   A . n 
A 1 150 ALA 150 149 ?   ?   ?   A . n 
A 1 151 GLU 151 150 ?   ?   ?   A . n 
A 1 152 ASP 152 151 ?   ?   ?   A . n 
A 1 153 GLU 153 152 ?   ?   ?   A . n 
A 1 154 ALA 154 153 ?   ?   ?   A . n 
A 1 155 GLU 155 154 ?   ?   ?   A . n 
A 1 156 ALA 156 155 ?   ?   ?   A . n 
A 1 157 ALA 157 156 ?   ?   ?   A . n 
A 1 158 ALA 158 157 ?   ?   ?   A . n 
A 1 159 ALA 159 158 ?   ?   ?   A . n 
A 1 160 ALA 160 159 ?   ?   ?   A . n 
A 1 161 LYS 161 160 ?   ?   ?   A . n 
A 1 162 PHE 162 161 ?   ?   ?   A . n 
A 1 163 THR 163 162 162 THR THR A . n 
A 1 164 GLY 164 163 163 GLY GLY A . n 
A 1 165 LEU 165 164 164 LEU LEU A . n 
A 1 166 SER 166 165 165 SER SER A . n 
A 1 167 LYS 167 166 166 LYS LYS A . n 
A 1 168 GLU 168 167 167 GLU GLU A . n 
A 1 169 GLU 169 168 168 GLU GLU A . n 
A 1 170 LEU 170 169 169 LEU LEU A . n 
A 1 171 LEU 171 170 170 LEU LEU A . n 
A 1 172 LYS 172 171 171 LYS LYS A . n 
A 1 173 VAL 173 172 172 VAL VAL A . n 
A 1 174 ALA 174 173 173 ALA ALA A . n 
A 1 175 GLY 175 174 174 GLY GLY A . n 
A 1 176 SER 176 175 175 SER SER A . n 
A 1 177 PRO 177 176 176 PRO PRO A . n 
A 1 178 GLY 178 177 177 GLY GLY A . n 
A 1 179 TRP 179 178 178 TRP TRP A . n 
A 1 180 VAL 180 179 179 VAL VAL A . n 
A 1 181 ARG 181 180 180 ARG ARG A . n 
A 1 182 THR 182 181 181 THR THR A . n 
A 1 183 ARG 183 182 182 ARG ARG A . n 
A 1 184 TRP 184 183 183 TRP TRP A . n 
A 1 185 ALA 185 184 184 ALA ALA A . n 
A 1 186 LEU 186 185 185 LEU LEU A . n 
A 1 187 LEU 187 186 186 LEU LEU A . n 
A 1 188 LEU 188 187 187 LEU LEU A . n 
A 1 189 LEU 189 188 188 LEU LEU A . n 
A 1 190 PHE 190 189 189 PHE PHE A . n 
A 1 191 TRP 191 190 190 TRP TRP A . n 
A 1 192 LEU 192 191 191 LEU LEU A . n 
A 1 193 GLY 193 192 192 GLY GLY A . n 
A 1 194 TRP 194 193 193 TRP TRP A . n 
A 1 195 LEU 195 194 194 LEU LEU A . n 
A 1 196 GLY 196 195 195 GLY GLY A . n 
A 1 197 MET 197 196 196 MET MET A . n 
A 1 198 LEU 198 197 197 LEU LEU A . n 
A 1 199 ALA 199 198 198 ALA ALA A . n 
A 1 200 GLY 200 199 199 GLY GLY A . n 
A 1 201 ALA 201 200 200 ALA ALA A . n 
A 1 202 VAL 202 201 201 VAL VAL A . n 
A 1 203 VAL 203 202 202 VAL VAL A . n 
A 1 204 ILE 204 203 203 ILE ILE A . n 
A 1 205 ILE 205 204 204 ILE ILE A . n 
A 1 206 VAL 206 205 205 VAL VAL A . n 
A 1 207 ARG 207 206 206 ARG ARG A . n 
A 1 208 ALA 208 207 207 ALA ALA A . n 
A 1 209 PRO 209 208 208 PRO PRO A . n 
A 1 210 ARG 210 209 209 ARG ARG A . n 
A 1 211 CYS 211 210 210 CYS CYS A . n 
A 1 212 ARG 212 211 211 ARG ARG A . n 
A 1 213 GLU 213 212 212 GLU GLU A . n 
A 1 214 LEU 214 213 213 LEU LEU A . n 
A 1 215 PRO 215 214 214 PRO PRO A . n 
A 1 216 ALA 216 215 215 ALA ALA A . n 
A 1 217 GLN 217 216 216 GLN GLN A . n 
A 1 218 LYS 218 217 217 LYS LYS A . n 
A 1 219 TRP 219 218 218 TRP TRP A . n 
A 1 220 TRP 220 219 219 TRP TRP A . n 
A 1 221 HIS 221 220 220 HIS HIS A . n 
A 1 222 THR 222 221 221 THR THR A . n 
A 1 223 GLY 223 222 222 GLY GLY A . n 
A 1 224 ALA 224 223 223 ALA ALA A . n 
A 1 225 LEU 225 224 224 LEU LEU A . n 
A 1 226 TYR 226 225 225 TYR TYR A . n 
A 1 227 ARG 227 226 226 ARG ARG A . n 
A 1 228 ILE 228 227 227 ILE ILE A . n 
A 1 229 GLY 229 228 228 GLY GLY A . n 
A 1 230 ASP 230 229 229 ASP ASP A . n 
A 1 231 LEU 231 230 230 LEU LEU A . n 
A 1 232 GLN 232 231 231 GLN GLN A . n 
A 1 233 ALA 233 232 232 ALA ALA A . n 
A 1 234 PHE 234 233 233 PHE PHE A . n 
A 1 235 GLN 235 234 234 GLN GLN A . n 
A 1 236 GLY 236 235 235 GLY GLY A . n 
A 1 237 HIS 237 236 236 HIS HIS A . n 
A 1 238 GLY 238 237 237 GLY GLY A . n 
A 1 239 ALA 239 238 238 ALA ALA A . n 
A 1 240 GLY 240 239 239 GLY GLY A . n 
A 1 241 ASN 241 240 240 ASN ASN A . n 
A 1 242 LEU 242 241 241 LEU LEU A . n 
A 1 243 ALA 243 242 242 ALA ALA A . n 
A 1 244 GLY 244 243 243 GLY GLY A . n 
A 1 245 LEU 245 244 244 LEU LEU A . n 
A 1 246 LYS 246 245 245 LYS LYS A . n 
A 1 247 GLY 247 246 246 GLY GLY A . n 
A 1 248 ARG 248 247 247 ARG ARG A . n 
A 1 249 LEU 249 248 248 LEU LEU A . n 
A 1 250 ASP 250 249 249 ASP ASP A . n 
A 1 251 TYR 251 250 250 TYR TYR A . n 
A 1 252 LEU 252 251 251 LEU LEU A . n 
A 1 253 SER 253 252 252 SER SER A . n 
A 1 254 SER 254 253 253 SER SER A . n 
A 1 255 LEU 255 254 254 LEU LEU A . n 
A 1 256 LYS 256 255 255 LYS LYS A . n 
A 1 257 VAL 257 256 256 VAL VAL A . n 
A 1 258 LYS 258 257 257 LYS LYS A . n 
A 1 259 GLY 259 258 258 GLY GLY A . n 
A 1 260 LEU 260 259 259 LEU LEU A . n 
A 1 261 VAL 261 260 260 VAL VAL A . n 
A 1 262 LEU 262 261 261 LEU LEU A . n 
A 1 263 GLY 263 262 262 GLY GLY A . n 
A 1 264 PRO 264 263 263 PRO PRO A . n 
A 1 265 ILE 265 264 264 ILE ILE A . n 
A 1 266 HIS 266 265 265 HIS HIS A . n 
A 1 267 LYS 267 266 266 LYS LYS A . n 
A 1 268 ASN 268 267 267 ASN ASN A . n 
A 1 269 GLN 269 268 268 GLN GLN A . n 
A 1 270 LYS 270 269 269 LYS LYS A . n 
A 1 271 ASP 271 270 270 ASP ASP A . n 
A 1 272 ASP 272 271 271 ASP ASP A . n 
A 1 273 VAL 273 272 272 VAL VAL A . n 
A 1 274 ALA 274 273 273 ALA ALA A . n 
A 1 275 GLN 275 274 274 GLN GLN A . n 
A 1 276 THR 276 275 275 THR THR A . n 
A 1 277 ASP 277 276 276 ASP ASP A . n 
A 1 278 LEU 278 277 277 LEU LEU A . n 
A 1 279 LEU 279 278 278 LEU LEU A . n 
A 1 280 GLN 280 279 279 GLN GLN A . n 
A 1 281 ILE 281 280 280 ILE ILE A . n 
A 1 282 ASP 282 281 281 ASP ASP A . n 
A 1 283 PRO 283 282 282 PRO PRO A . n 
A 1 284 ASN 284 283 283 ASN ASN A . n 
A 1 285 PHE 285 284 284 PHE PHE A . n 
A 1 286 GLY 286 285 285 GLY GLY A . n 
A 1 287 SER 287 286 286 SER SER A . n 
A 1 288 LYS 288 287 287 LYS LYS A . n 
A 1 289 GLU 289 288 288 GLU GLU A . n 
A 1 290 ASP 290 289 289 ASP ASP A . n 
A 1 291 PHE 291 290 290 PHE PHE A . n 
A 1 292 ASP 292 291 291 ASP ASP A . n 
A 1 293 SER 293 292 292 SER SER A . n 
A 1 294 LEU 294 293 293 LEU LEU A . n 
A 1 295 LEU 295 294 294 LEU LEU A . n 
A 1 296 GLN 296 295 295 GLN GLN A . n 
A 1 297 SER 297 296 296 SER SER A . n 
A 1 298 ALA 298 297 297 ALA ALA A . n 
A 1 299 LYS 299 298 298 LYS LYS A . n 
A 1 300 LYS 300 299 299 LYS LYS A . n 
A 1 301 LYS 301 300 300 LYS LYS A . n 
A 1 302 SER 302 301 301 SER SER A . n 
A 1 303 ILE 303 302 302 ILE ILE A . n 
A 1 304 ARG 304 303 303 ARG ARG A . n 
A 1 305 VAL 305 304 304 VAL VAL A . n 
A 1 306 ILE 306 305 305 ILE ILE A . n 
A 1 307 LEU 307 306 306 LEU LEU A . n 
A 1 308 ASP 308 307 307 ASP ASP A . n 
A 1 309 LEU 309 308 308 LEU LEU A . n 
A 1 310 THR 310 309 309 THR THR A . n 
A 1 311 PRO 311 310 310 PRO PRO A . n 
A 1 312 ASN 312 311 311 ASN ASN A . n 
A 1 313 TYR 313 312 312 TYR TYR A . n 
A 1 314 ARG 314 313 313 ARG ARG A . n 
A 1 315 GLY 315 314 314 GLY GLY A . n 
A 1 316 GLU 316 315 315 GLU GLU A . n 
A 1 317 ASN 317 316 316 ASN ASN A . n 
A 1 318 SER 318 317 317 SER SER A . n 
A 1 319 TRP 319 318 318 TRP TRP A . n 
A 1 320 PHE 320 319 319 PHE PHE A . n 
A 1 321 SER 321 320 320 SER SER A . n 
A 1 322 THR 322 321 321 THR THR A . n 
A 1 323 GLN 323 322 322 GLN GLN A . n 
A 1 324 VAL 324 323 323 VAL VAL A . n 
A 1 325 ASP 325 324 324 ASP ASP A . n 
A 1 326 THR 326 325 325 THR THR A . n 
A 1 327 VAL 327 326 326 VAL VAL A . n 
A 1 328 ALA 328 327 327 ALA ALA A . n 
A 1 329 THR 329 328 328 THR THR A . n 
A 1 330 LYS 330 329 329 LYS LYS A . n 
A 1 331 VAL 331 330 330 VAL VAL A . n 
A 1 332 LYS 332 331 331 LYS LYS A . n 
A 1 333 ASP 333 332 332 ASP ASP A . n 
A 1 334 ALA 334 333 333 ALA ALA A . n 
A 1 335 LEU 335 334 334 LEU LEU A . n 
A 1 336 GLU 336 335 335 GLU GLU A . n 
A 1 337 PHE 337 336 336 PHE PHE A . n 
A 1 338 TRP 338 337 337 TRP TRP A . n 
A 1 339 LEU 339 338 338 LEU LEU A . n 
A 1 340 GLN 340 339 339 GLN GLN A . n 
A 1 341 ALA 341 340 340 ALA ALA A . n 
A 1 342 GLY 342 341 341 GLY GLY A . n 
A 1 343 VAL 343 342 342 VAL VAL A . n 
A 1 344 ASP 344 343 343 ASP ASP A . n 
A 1 345 GLY 345 344 344 GLY GLY A . n 
A 1 346 PHE 346 345 345 PHE PHE A . n 
A 1 347 GLN 347 346 346 GLN GLN A . n 
A 1 348 VAL 348 347 347 VAL VAL A . n 
A 1 349 ARG 349 348 348 ARG ARG A . n 
A 1 350 ASP 350 349 349 ASP ASP A . n 
A 1 351 ILE 351 350 350 ILE ILE A . n 
A 1 352 GLU 352 351 351 GLU GLU A . n 
A 1 353 ASN 353 352 352 ASN ASN A . n 
A 1 354 LEU 354 353 353 LEU LEU A . n 
A 1 355 LYS 355 354 354 LYS LYS A . n 
A 1 356 ASP 356 355 355 ASP ASP A . n 
A 1 357 ALA 357 356 356 ALA ALA A . n 
A 1 358 SER 358 357 357 SER SER A . n 
A 1 359 SER 359 358 358 SER SER A . n 
A 1 360 PHE 360 359 359 PHE PHE A . n 
A 1 361 LEU 361 360 360 LEU LEU A . n 
A 1 362 ALA 362 361 361 ALA ALA A . n 
A 1 363 GLU 363 362 362 GLU GLU A . n 
A 1 364 TRP 364 363 363 TRP TRP A . n 
A 1 365 GLN 365 364 364 GLN GLN A . n 
A 1 366 ASN 366 365 365 ASN ASN A . n 
A 1 367 ILE 367 366 366 ILE ILE A . n 
A 1 368 THR 368 367 367 THR THR A . n 
A 1 369 LYS 369 368 368 LYS LYS A . n 
A 1 370 GLY 370 369 369 GLY GLY A . n 
A 1 371 PHE 371 370 370 PHE PHE A . n 
A 1 372 SER 372 371 371 SER SER A . n 
A 1 373 GLU 373 372 372 GLU GLU A . n 
A 1 374 ASP 374 373 373 ASP ASP A . n 
A 1 375 ARG 375 374 374 ARG ARG A . n 
A 1 376 LEU 376 375 375 LEU LEU A . n 
A 1 377 LEU 377 376 376 LEU LEU A . n 
A 1 378 ILE 378 377 377 ILE ILE A . n 
A 1 379 ALA 379 378 378 ALA ALA A . n 
A 1 380 GLY 380 379 379 GLY GLY A . n 
A 1 381 THR 381 380 380 THR THR A . n 
A 1 382 ASN 382 381 381 ASN ASN A . n 
A 1 383 SER 383 382 382 SER SER A . n 
A 1 384 SER 384 383 383 SER SER A . n 
A 1 385 ASP 385 384 384 ASP ASP A . n 
A 1 386 LEU 386 385 385 LEU LEU A . n 
A 1 387 GLN 387 386 386 GLN GLN A . n 
A 1 388 GLN 388 387 387 GLN GLN A . n 
A 1 389 ILE 389 388 388 ILE ILE A . n 
A 1 390 LEU 390 389 389 LEU LEU A . n 
A 1 391 SER 391 390 390 SER SER A . n 
A 1 392 LEU 392 391 391 LEU LEU A . n 
A 1 393 LEU 393 392 392 LEU LEU A . n 
A 1 394 GLU 394 393 393 GLU GLU A . n 
A 1 395 SER 395 394 394 SER SER A . n 
A 1 396 ASN 396 395 395 ASN ASN A . n 
A 1 397 LYS 397 396 396 LYS LYS A . n 
A 1 398 ASP 398 397 397 ASP ASP A . n 
A 1 399 LEU 399 398 398 LEU LEU A . n 
A 1 400 LEU 400 399 399 LEU LEU A . n 
A 1 401 LEU 401 400 400 LEU LEU A . n 
A 1 402 THR 402 401 401 THR THR A . n 
A 1 403 SER 403 402 402 SER SER A . n 
A 1 404 SER 404 403 403 SER SER A . n 
A 1 405 TYR 405 404 404 TYR TYR A . n 
A 1 406 LEU 406 405 405 LEU LEU A . n 
A 1 407 SER 407 406 406 SER SER A . n 
A 1 408 ASP 408 407 407 ASP ASP A . n 
A 1 409 SER 409 408 408 SER SER A . n 
A 1 410 GLY 410 409 409 GLY GLY A . n 
A 1 411 SER 411 410 410 SER SER A . n 
A 1 412 THR 412 411 411 THR THR A . n 
A 1 413 GLY 413 412 412 GLY GLY A . n 
A 1 414 GLU 414 413 413 GLU GLU A . n 
A 1 415 HIS 415 414 414 HIS HIS A . n 
A 1 416 THR 416 415 415 THR THR A . n 
A 1 417 LYS 417 416 416 LYS LYS A . n 
A 1 418 SER 418 417 417 SER SER A . n 
A 1 419 LEU 419 418 418 LEU LEU A . n 
A 1 420 VAL 420 419 419 VAL VAL A . n 
A 1 421 THR 421 420 420 THR THR A . n 
A 1 422 GLN 422 421 421 GLN GLN A . n 
A 1 423 TYR 423 422 422 TYR TYR A . n 
A 1 424 LEU 424 423 423 LEU LEU A . n 
A 1 425 ASN 425 424 424 ASN ASN A . n 
A 1 426 ALA 426 425 425 ALA ALA A . n 
A 1 427 THR 427 426 426 THR THR A . n 
A 1 428 GLY 428 427 427 GLY GLY A . n 
A 1 429 ASN 429 428 428 ASN ASN A . n 
A 1 430 ARG 430 429 429 ARG ARG A . n 
A 1 431 TRP 431 430 430 TRP TRP A . n 
A 1 432 CYS 432 431 431 CYS CYS A . n 
A 1 433 SER 433 432 432 SER SER A . n 
A 1 434 TRP 434 433 433 TRP TRP A . n 
A 1 435 SER 435 434 434 SER SER A . n 
A 1 436 LEU 436 435 435 LEU LEU A . n 
A 1 437 SER 437 436 436 SER SER A . n 
A 1 438 GLN 438 437 437 GLN GLN A . n 
A 1 439 ALA 439 438 438 ALA ALA A . n 
A 1 440 ARG 440 439 439 ARG ARG A . n 
A 1 441 LEU 441 440 440 LEU LEU A . n 
A 1 442 LEU 442 441 441 LEU LEU A . n 
A 1 443 THR 443 442 442 THR THR A . n 
A 1 444 SER 444 443 443 SER SER A . n 
A 1 445 PHE 445 444 444 PHE PHE A . n 
A 1 446 LEU 446 445 445 LEU LEU A . n 
A 1 447 PRO 447 446 446 PRO PRO A . n 
A 1 448 ALA 448 447 447 ALA ALA A . n 
A 1 449 GLN 449 448 448 GLN GLN A . n 
A 1 450 LEU 450 449 449 LEU LEU A . n 
A 1 451 LEU 451 450 450 LEU LEU A . n 
A 1 452 ARG 452 451 451 ARG ARG A . n 
A 1 453 LEU 453 452 452 LEU LEU A . n 
A 1 454 TYR 454 453 453 TYR TYR A . n 
A 1 455 GLN 455 454 454 GLN GLN A . n 
A 1 456 LEU 456 455 455 LEU LEU A . n 
A 1 457 MET 457 456 456 MET MET A . n 
A 1 458 LEU 458 457 457 LEU LEU A . n 
A 1 459 PHE 459 458 458 PHE PHE A . n 
A 1 460 THR 460 459 459 THR THR A . n 
A 1 461 LEU 461 460 460 LEU LEU A . n 
A 1 462 PRO 462 461 461 PRO PRO A . n 
A 1 463 GLY 463 462 462 GLY GLY A . n 
A 1 464 THR 464 463 463 THR THR A . n 
A 1 465 PRO 465 464 464 PRO PRO A . n 
A 1 466 VAL 466 465 465 VAL VAL A . n 
A 1 467 PHE 467 466 466 PHE PHE A . n 
A 1 468 SER 468 467 467 SER SER A . n 
A 1 469 TYR 469 468 468 TYR TYR A . n 
A 1 470 GLY 470 469 469 GLY GLY A . n 
A 1 471 ASP 471 470 470 ASP ASP A . n 
A 1 472 GLU 472 471 471 GLU GLU A . n 
A 1 473 ILE 473 472 472 ILE ILE A . n 
A 1 474 GLY 474 473 473 GLY GLY A . n 
A 1 475 LEU 475 474 474 LEU LEU A . n 
A 1 476 ASP 476 475 475 ASP ASP A . n 
A 1 477 ALA 477 476 476 ALA ALA A . n 
A 1 478 ALA 478 477 477 ALA ALA A . n 
A 1 479 ALA 479 478 478 ALA ALA A . n 
A 1 480 LEU 480 479 479 LEU LEU A . n 
A 1 481 PRO 481 480 480 PRO PRO A . n 
A 1 482 GLY 482 481 481 GLY GLY A . n 
A 1 483 GLN 483 482 482 GLN GLN A . n 
A 1 484 PRO 484 483 483 PRO PRO A . n 
A 1 485 MET 485 484 484 MET MET A . n 
A 1 486 GLU 486 485 485 GLU GLU A . n 
A 1 487 ALA 487 486 486 ALA ALA A . n 
A 1 488 PRO 488 487 487 PRO PRO A . n 
A 1 489 VAL 489 488 488 VAL VAL A . n 
A 1 490 MET 490 489 489 MET MET A . n 
A 1 491 LEU 491 490 490 LEU LEU A . n 
A 1 492 TRP 492 491 491 TRP TRP A . n 
A 1 493 ASP 493 492 492 ASP ASP A . n 
A 1 494 GLU 494 493 493 GLU GLU A . n 
A 1 495 SER 495 494 494 SER SER A . n 
A 1 496 SER 496 495 495 SER SER A . n 
A 1 497 PHE 497 496 496 PHE PHE A . n 
A 1 498 PRO 498 497 497 PRO PRO A . n 
A 1 499 ASP 499 498 498 ASP ASP A . n 
A 1 500 ILE 500 499 499 ILE ILE A . n 
A 1 501 PRO 501 500 500 PRO PRO A . n 
A 1 502 GLY 502 501 501 GLY GLY A . n 
A 1 503 ALA 503 502 502 ALA ALA A . n 
A 1 504 VAL 504 503 503 VAL VAL A . n 
A 1 505 SER 505 504 504 SER SER A . n 
A 1 506 ALA 506 505 505 ALA ALA A . n 
A 1 507 ASN 507 506 506 ASN ASN A . n 
A 1 508 MET 508 507 507 MET MET A . n 
A 1 509 THR 509 508 508 THR THR A . n 
A 1 510 VAL 510 509 509 VAL VAL A . n 
A 1 511 LYS 511 510 510 LYS LYS A . n 
A 1 512 GLY 512 511 511 GLY GLY A . n 
A 1 513 GLN 513 512 512 GLN GLN A . n 
A 1 514 SER 514 513 513 SER SER A . n 
A 1 515 GLU 515 514 514 GLU GLU A . n 
A 1 516 ASP 516 515 515 ASP ASP A . n 
A 1 517 PRO 517 516 516 PRO PRO A . n 
A 1 518 GLY 518 517 517 GLY GLY A . n 
A 1 519 SER 519 518 518 SER SER A . n 
A 1 520 LEU 520 519 519 LEU LEU A . n 
A 1 521 LEU 521 520 520 LEU LEU A . n 
A 1 522 SER 522 521 521 SER SER A . n 
A 1 523 LEU 523 522 522 LEU LEU A . n 
A 1 524 PHE 524 523 523 PHE PHE A . n 
A 1 525 ARG 525 524 524 ARG ARG A . n 
A 1 526 ARG 526 525 525 ARG ARG A . n 
A 1 527 LEU 527 526 526 LEU LEU A . n 
A 1 528 SER 528 527 527 SER SER A . n 
A 1 529 ASP 529 528 528 ASP ASP A . n 
A 1 530 GLN 530 529 529 GLN GLN A . n 
A 1 531 ARG 531 530 530 ARG ARG A . n 
A 1 532 SER 532 531 531 SER SER A . n 
A 1 533 LYS 533 532 532 LYS LYS A . n 
A 1 534 GLU 534 533 533 GLU GLU A . n 
A 1 535 ARG 535 534 534 ARG ARG A . n 
A 1 536 SER 536 535 535 SER SER A . n 
A 1 537 LEU 537 536 536 LEU LEU A . n 
A 1 538 LEU 538 537 537 LEU LEU A . n 
A 1 539 HIS 539 538 538 HIS HIS A . n 
A 1 540 GLY 540 539 539 GLY GLY A . n 
A 1 541 ASP 541 540 540 ASP ASP A . n 
A 1 542 PHE 542 541 541 PHE PHE A . n 
A 1 543 HIS 543 542 542 HIS HIS A . n 
A 1 544 ALA 544 543 543 ALA ALA A . n 
A 1 545 PHE 545 544 544 PHE PHE A . n 
A 1 546 SER 546 545 545 SER SER A . n 
A 1 547 ALA 547 546 546 ALA ALA A . n 
A 1 548 GLY 548 547 547 GLY GLY A . n 
A 1 549 PRO 549 548 548 PRO PRO A . n 
A 1 550 GLY 550 549 549 GLY GLY A . n 
A 1 551 LEU 551 550 550 LEU LEU A . n 
A 1 552 PHE 552 551 551 PHE PHE A . n 
A 1 553 SER 553 552 552 SER SER A . n 
A 1 554 TYR 554 553 553 TYR TYR A . n 
A 1 555 ILE 555 554 554 ILE ILE A . n 
A 1 556 ARG 556 555 555 ARG ARG A . n 
A 1 557 HIS 557 556 556 HIS HIS A . n 
A 1 558 TRP 558 557 557 TRP TRP A . n 
A 1 559 ASP 559 558 558 ASP ASP A . n 
A 1 560 GLN 560 559 559 GLN GLN A . n 
A 1 561 ASN 561 560 560 ASN ASN A . n 
A 1 562 GLU 562 561 561 GLU GLU A . n 
A 1 563 ARG 563 562 562 ARG ARG A . n 
A 1 564 PHE 564 563 563 PHE PHE A . n 
A 1 565 LEU 565 564 564 LEU LEU A . n 
A 1 566 VAL 566 565 565 VAL VAL A . n 
A 1 567 VAL 567 566 566 VAL VAL A . n 
A 1 568 LEU 568 567 567 LEU LEU A . n 
A 1 569 ASN 569 568 568 ASN ASN A . n 
A 1 570 PHE 570 569 569 PHE PHE A . n 
A 1 571 GLY 571 570 570 GLY GLY A . n 
A 1 572 ASP 572 571 571 ASP ASP A . n 
A 1 573 VAL 573 572 572 VAL VAL A . n 
A 1 574 GLY 574 573 573 GLY GLY A . n 
A 1 575 LEU 575 574 574 LEU LEU A . n 
A 1 576 SER 576 575 575 SER SER A . n 
A 1 577 ALA 577 576 576 ALA ALA A . n 
A 1 578 GLY 578 577 577 GLY GLY A . n 
A 1 579 LEU 579 578 578 LEU LEU A . n 
A 1 580 GLN 580 579 579 GLN GLN A . n 
A 1 581 ALA 581 580 580 ALA ALA A . n 
A 1 582 SER 582 581 581 SER SER A . n 
A 1 583 ASP 583 582 582 ASP ASP A . n 
A 1 584 LEU 584 583 583 LEU LEU A . n 
A 1 585 PRO 585 584 584 PRO PRO A . n 
A 1 586 ALA 586 585 585 ALA ALA A . n 
A 1 587 SER 587 586 586 SER SER A . n 
A 1 588 ALA 588 587 587 ALA ALA A . n 
A 1 589 SER 589 588 588 SER SER A . n 
A 1 590 LEU 590 589 589 LEU LEU A . n 
A 1 591 PRO 591 590 590 PRO PRO A . n 
A 1 592 ALA 592 591 591 ALA ALA A . n 
A 1 593 LYS 593 592 592 LYS LYS A . n 
A 1 594 ALA 594 593 593 ALA ALA A . n 
A 1 595 ASP 595 594 594 ASP ASP A . n 
A 1 596 LEU 596 595 595 LEU LEU A . n 
A 1 597 LEU 597 596 596 LEU LEU A . n 
A 1 598 LEU 598 597 597 LEU LEU A . n 
A 1 599 SER 599 598 598 SER SER A . n 
A 1 600 THR 600 599 599 THR THR A . n 
A 1 601 GLN 601 600 600 GLN GLN A . n 
A 1 602 PRO 602 601 601 PRO PRO A . n 
A 1 603 GLY 603 602 602 GLY GLY A . n 
A 1 604 ARG 604 603 603 ARG ARG A . n 
A 1 605 GLU 605 604 604 GLU GLU A . n 
A 1 606 GLU 606 605 605 GLU GLU A . n 
A 1 607 GLY 607 606 606 GLY GLY A . n 
A 1 608 SER 608 607 607 SER SER A . n 
A 1 609 PRO 609 608 608 PRO PRO A . n 
A 1 610 LEU 610 609 609 LEU LEU A . n 
A 1 611 GLU 611 610 610 GLU GLU A . n 
A 1 612 LEU 612 611 611 LEU LEU A . n 
A 1 613 GLU 613 612 612 GLU GLU A . n 
A 1 614 ARG 614 613 613 ARG ARG A . n 
A 1 615 LEU 615 614 614 LEU LEU A . n 
A 1 616 LYS 616 615 615 LYS LYS A . n 
A 1 617 LEU 617 616 616 LEU LEU A . n 
A 1 618 GLU 618 617 617 GLU GLU A . n 
A 1 619 PRO 619 618 618 PRO PRO A . n 
A 1 620 HIS 620 619 619 HIS HIS A . n 
A 1 621 GLU 621 620 620 GLU GLU A . n 
A 1 622 GLY 622 621 621 GLY GLY A . n 
A 1 623 LEU 623 622 622 LEU LEU A . n 
A 1 624 LEU 624 623 623 LEU LEU A . n 
A 1 625 LEU 625 624 624 LEU LEU A . n 
A 1 626 ARG 626 625 625 ARG ARG A . n 
A 1 627 PHE 627 626 626 PHE PHE A . n 
A 1 628 PRO 628 627 627 PRO PRO A . n 
A 1 629 TYR 629 628 628 TYR TYR A . n 
A 1 630 ALA 630 629 629 ALA ALA A . n 
A 1 631 ALA 631 630 630 ALA ALA A . n 
B 2 1   MET 1   1   ?   ?   ?   B . n 
B 2 2   ALA 2   2   ?   ?   ?   B . n 
B 2 3   GLY 3   3   ?   ?   ?   B . n 
B 2 4   ALA 4   4   ?   ?   ?   B . n 
B 2 5   GLY 5   5   ?   ?   ?   B . n 
B 2 6   PRO 6   6   ?   ?   ?   B . n 
B 2 7   LYS 7   7   ?   ?   ?   B . n 
B 2 8   ARG 8   8   ?   ?   ?   B . n 
B 2 9   ARG 9   9   ?   ?   ?   B . n 
B 2 10  ALA 10  10  ?   ?   ?   B . n 
B 2 11  LEU 11  11  ?   ?   ?   B . n 
B 2 12  ALA 12  12  ?   ?   ?   B . n 
B 2 13  ALA 13  13  ?   ?   ?   B . n 
B 2 14  PRO 14  14  ?   ?   ?   B . n 
B 2 15  ALA 15  15  ?   ?   ?   B . n 
B 2 16  ALA 16  16  ?   ?   ?   B . n 
B 2 17  GLU 17  17  ?   ?   ?   B . n 
B 2 18  GLU 18  18  ?   ?   ?   B . n 
B 2 19  LYS 19  19  ?   ?   ?   B . n 
B 2 20  GLU 20  20  ?   ?   ?   B . n 
B 2 21  GLU 21  21  ?   ?   ?   B . n 
B 2 22  ALA 22  22  ?   ?   ?   B . n 
B 2 23  ARG 23  23  ?   ?   ?   B . n 
B 2 24  GLU 24  24  ?   ?   ?   B . n 
B 2 25  LYS 25  25  ?   ?   ?   B . n 
B 2 26  MET 26  26  ?   ?   ?   B . n 
B 2 27  LEU 27  27  ?   ?   ?   B . n 
B 2 28  ALA 28  28  ?   ?   ?   B . n 
B 2 29  ALA 29  29  ?   ?   ?   B . n 
B 2 30  LYS 30  30  ?   ?   ?   B . n 
B 2 31  SER 31  31  ?   ?   ?   B . n 
B 2 32  ALA 32  32  ?   ?   ?   B . n 
B 2 33  ASP 33  33  ?   ?   ?   B . n 
B 2 34  GLY 34  34  ?   ?   ?   B . n 
B 2 35  SER 35  35  ?   ?   ?   B . n 
B 2 36  ALA 36  36  ?   ?   ?   B . n 
B 2 37  PRO 37  37  ?   ?   ?   B . n 
B 2 38  ALA 38  38  ?   ?   ?   B . n 
B 2 39  GLY 39  39  ?   ?   ?   B . n 
B 2 40  GLU 40  40  ?   ?   ?   B . n 
B 2 41  GLY 41  41  ?   ?   ?   B . n 
B 2 42  GLU 42  42  ?   ?   ?   B . n 
B 2 43  GLY 43  43  ?   ?   ?   B . n 
B 2 44  VAL 44  44  44  VAL VAL B . n 
B 2 45  THR 45  45  45  THR THR B . n 
B 2 46  LEU 46  46  46  LEU LEU B . n 
B 2 47  GLN 47  47  47  GLN GLN B . n 
B 2 48  ARG 48  48  48  ARG ARG B . n 
B 2 49  ASN 49  49  49  ASN ASN B . n 
B 2 50  ILE 50  50  50  ILE ILE B . n 
B 2 51  THR 51  51  51  THR THR B . n 
B 2 52  LEU 52  52  52  LEU LEU B . n 
B 2 53  LEU 53  53  53  LEU LEU B . n 
B 2 54  ASN 54  54  54  ASN ASN B . n 
B 2 55  GLY 55  55  55  GLY GLY B . n 
B 2 56  VAL 56  56  56  VAL VAL B . n 
B 2 57  ALA 57  57  57  ALA ALA B . n 
B 2 58  ILE 58  58  58  ILE ILE B . n 
B 2 59  ILE 59  59  59  ILE ILE B . n 
B 2 60  VAL 60  60  60  VAL VAL B . n 
B 2 61  GLY 61  61  61  GLY GLY B . n 
B 2 62  THR 62  62  62  THR THR B . n 
B 2 63  ILE 63  63  63  ILE ILE B . n 
B 2 64  ILE 64  64  64  ILE ILE B . n 
B 2 65  GLY 65  65  65  GLY GLY B . n 
B 2 66  SER 66  66  66  SER SER B . n 
B 2 67  GLY 67  67  67  GLY GLY B . n 
B 2 68  ILE 68  68  68  ILE ILE B . n 
B 2 69  PHE 69  69  69  PHE PHE B . n 
B 2 70  VAL 70  70  70  VAL VAL B . n 
B 2 71  THR 71  71  71  THR THR B . n 
B 2 72  PRO 72  72  72  PRO PRO B . n 
B 2 73  THR 73  73  73  THR THR B . n 
B 2 74  GLY 74  74  74  GLY GLY B . n 
B 2 75  VAL 75  75  75  VAL VAL B . n 
B 2 76  LEU 76  76  76  LEU LEU B . n 
B 2 77  LYS 77  77  77  LYS LYS B . n 
B 2 78  GLU 78  78  78  GLU GLU B . n 
B 2 79  ALA 79  79  79  ALA ALA B . n 
B 2 80  GLY 80  80  80  GLY GLY B . n 
B 2 81  SER 81  81  81  SER SER B . n 
B 2 82  PRO 82  82  82  PRO PRO B . n 
B 2 83  GLY 83  83  83  GLY GLY B . n 
B 2 84  LEU 84  84  84  LEU LEU B . n 
B 2 85  ALA 85  85  85  ALA ALA B . n 
B 2 86  LEU 86  86  86  LEU LEU B . n 
B 2 87  VAL 87  87  87  VAL VAL B . n 
B 2 88  VAL 88  88  88  VAL VAL B . n 
B 2 89  TRP 89  89  89  TRP TRP B . n 
B 2 90  ALA 90  90  90  ALA ALA B . n 
B 2 91  ALA 91  91  91  ALA ALA B . n 
B 2 92  CYS 92  92  92  CYS CYS B . n 
B 2 93  GLY 93  93  93  GLY GLY B . n 
B 2 94  VAL 94  94  94  VAL VAL B . n 
B 2 95  PHE 95  95  95  PHE PHE B . n 
B 2 96  SER 96  96  96  SER SER B . n 
B 2 97  ILE 97  97  97  ILE ILE B . n 
B 2 98  VAL 98  98  98  VAL VAL B . n 
B 2 99  GLY 99  99  99  GLY GLY B . n 
B 2 100 ALA 100 100 100 ALA ALA B . n 
B 2 101 LEU 101 101 101 LEU LEU B . n 
B 2 102 CYS 102 102 102 CYS CYS B . n 
B 2 103 TYR 103 103 103 TYR TYR B . n 
B 2 104 ALA 104 104 104 ALA ALA B . n 
B 2 105 GLU 105 105 105 GLU GLU B . n 
B 2 106 LEU 106 106 106 LEU LEU B . n 
B 2 107 GLY 107 107 107 GLY GLY B . n 
B 2 108 THR 108 108 108 THR THR B . n 
B 2 109 THR 109 109 109 THR THR B . n 
B 2 110 ILE 110 110 110 ILE ILE B . n 
B 2 111 SER 111 111 111 SER SER B . n 
B 2 112 LYS 112 112 112 LYS LYS B . n 
B 2 113 SER 113 113 113 SER SER B . n 
B 2 114 GLY 114 114 114 GLY GLY B . n 
B 2 115 GLY 115 115 115 GLY GLY B . n 
B 2 116 ASP 116 116 116 ASP ASP B . n 
B 2 117 TYR 117 117 117 TYR TYR B . n 
B 2 118 ALA 118 118 118 ALA ALA B . n 
B 2 119 TYR 119 119 119 TYR TYR B . n 
B 2 120 MET 120 120 120 MET MET B . n 
B 2 121 LEU 121 121 121 LEU LEU B . n 
B 2 122 GLU 122 122 122 GLU GLU B . n 
B 2 123 VAL 123 123 123 VAL VAL B . n 
B 2 124 TYR 124 124 124 TYR TYR B . n 
B 2 125 GLY 125 125 125 GLY GLY B . n 
B 2 126 SER 126 126 126 SER SER B . n 
B 2 127 LEU 127 127 127 LEU LEU B . n 
B 2 128 PRO 128 128 128 PRO PRO B . n 
B 2 129 ALA 129 129 129 ALA ALA B . n 
B 2 130 PHE 130 130 130 PHE PHE B . n 
B 2 131 LEU 131 131 131 LEU LEU B . n 
B 2 132 LYS 132 132 132 LYS LYS B . n 
B 2 133 LEU 133 133 133 LEU LEU B . n 
B 2 134 TRP 134 134 134 TRP TRP B . n 
B 2 135 ILE 135 135 135 ILE ILE B . n 
B 2 136 GLU 136 136 136 GLU GLU B . n 
B 2 137 LEU 137 137 137 LEU LEU B . n 
B 2 138 LEU 138 138 138 LEU LEU B . n 
B 2 139 ILE 139 139 139 ILE ILE B . n 
B 2 140 ILE 140 140 140 ILE ILE B . n 
B 2 141 ARG 141 141 141 ARG ARG B . n 
B 2 142 PRO 142 142 142 PRO PRO B . n 
B 2 143 SER 143 143 143 SER SER B . n 
B 2 144 SER 144 144 144 SER SER B . n 
B 2 145 GLN 145 145 145 GLN GLN B . n 
B 2 146 TYR 146 146 146 TYR TYR B . n 
B 2 147 ILE 147 147 147 ILE ILE B . n 
B 2 148 VAL 148 148 148 VAL VAL B . n 
B 2 149 ALA 149 149 149 ALA ALA B . n 
B 2 150 LEU 150 150 150 LEU LEU B . n 
B 2 151 VAL 151 151 151 VAL VAL B . n 
B 2 152 PHE 152 152 152 PHE PHE B . n 
B 2 153 ALA 153 153 153 ALA ALA B . n 
B 2 154 THR 154 154 154 THR THR B . n 
B 2 155 TYR 155 155 155 TYR TYR B . n 
B 2 156 LEU 156 156 156 LEU LEU B . n 
B 2 157 LEU 157 157 157 LEU LEU B . n 
B 2 158 LYS 158 158 158 LYS LYS B . n 
B 2 159 PRO 159 159 159 PRO PRO B . n 
B 2 160 LEU 160 160 160 LEU LEU B . n 
B 2 161 PHE 161 161 161 PHE PHE B . n 
B 2 162 PRO 162 162 162 PRO PRO B . n 
B 2 163 THR 163 163 163 THR THR B . n 
B 2 164 CYS 164 164 164 CYS CYS B . n 
B 2 165 PRO 165 165 165 PRO PRO B . n 
B 2 166 VAL 166 166 166 VAL VAL B . n 
B 2 167 PRO 167 167 167 PRO PRO B . n 
B 2 168 GLU 168 168 168 GLU GLU B . n 
B 2 169 GLU 169 169 169 GLU GLU B . n 
B 2 170 ALA 170 170 170 ALA ALA B . n 
B 2 171 ALA 171 171 171 ALA ALA B . n 
B 2 172 LYS 172 172 172 LYS LYS B . n 
B 2 173 LEU 173 173 173 LEU LEU B . n 
B 2 174 VAL 174 174 174 VAL VAL B . n 
B 2 175 ALA 175 175 175 ALA ALA B . n 
B 2 176 CYS 176 176 176 CYS CYS B . n 
B 2 177 LEU 177 177 177 LEU LEU B . n 
B 2 178 CYS 178 178 178 CYS CYS B . n 
B 2 179 VAL 179 179 179 VAL VAL B . n 
B 2 180 LEU 180 180 180 LEU LEU B . n 
B 2 181 LEU 181 181 181 LEU LEU B . n 
B 2 182 LEU 182 182 182 LEU LEU B . n 
B 2 183 THR 183 183 183 THR THR B . n 
B 2 184 ALA 184 184 184 ALA ALA B . n 
B 2 185 VAL 185 185 185 VAL VAL B . n 
B 2 186 ASN 186 186 186 ASN ASN B . n 
B 2 187 CYS 187 187 187 CYS CYS B . n 
B 2 188 TYR 188 188 188 TYR TYR B . n 
B 2 189 SER 189 189 189 SER SER B . n 
B 2 190 VAL 190 190 190 VAL VAL B . n 
B 2 191 LYS 191 191 191 LYS LYS B . n 
B 2 192 ALA 192 192 192 ALA ALA B . n 
B 2 193 ALA 193 193 193 ALA ALA B . n 
B 2 194 THR 194 194 194 THR THR B . n 
B 2 195 ARG 195 195 195 ARG ARG B . n 
B 2 196 VAL 196 196 196 VAL VAL B . n 
B 2 197 GLN 197 197 197 GLN GLN B . n 
B 2 198 ASP 198 198 198 ASP ASP B . n 
B 2 199 ALA 199 199 199 ALA ALA B . n 
B 2 200 PHE 200 200 200 PHE PHE B . n 
B 2 201 ALA 201 201 201 ALA ALA B . n 
B 2 202 ALA 202 202 202 ALA ALA B . n 
B 2 203 ALA 203 203 203 ALA ALA B . n 
B 2 204 LYS 204 204 204 LYS LYS B . n 
B 2 205 LEU 205 205 205 LEU LEU B . n 
B 2 206 LEU 206 206 206 LEU LEU B . n 
B 2 207 ALA 207 207 207 ALA ALA B . n 
B 2 208 LEU 208 208 208 LEU LEU B . n 
B 2 209 ALA 209 209 209 ALA ALA B . n 
B 2 210 LEU 210 210 210 LEU LEU B . n 
B 2 211 ILE 211 211 211 ILE ILE B . n 
B 2 212 ILE 212 212 212 ILE ILE B . n 
B 2 213 LEU 213 213 213 LEU LEU B . n 
B 2 214 LEU 214 214 214 LEU LEU B . n 
B 2 215 GLY 215 215 215 GLY GLY B . n 
B 2 216 PHE 216 216 216 PHE PHE B . n 
B 2 217 VAL 217 217 217 VAL VAL B . n 
B 2 218 GLN 218 218 218 GLN GLN B . n 
B 2 219 ILE 219 219 219 ILE ILE B . n 
B 2 220 GLY 220 220 220 GLY GLY B . n 
B 2 221 LYS 221 221 221 LYS LYS B . n 
B 2 222 GLY 222 222 222 GLY GLY B . n 
B 2 223 ASP 223 223 ?   ?   ?   B . n 
B 2 224 VAL 224 224 ?   ?   ?   B . n 
B 2 225 SER 225 225 ?   ?   ?   B . n 
B 2 226 ASN 226 226 ?   ?   ?   B . n 
B 2 227 LEU 227 227 ?   ?   ?   B . n 
B 2 228 ASP 228 228 ?   ?   ?   B . n 
B 2 229 PRO 229 229 ?   ?   ?   B . n 
B 2 230 ASN 230 230 ?   ?   ?   B . n 
B 2 231 PHE 231 231 ?   ?   ?   B . n 
B 2 232 SER 232 232 ?   ?   ?   B . n 
B 2 233 PHE 233 233 233 PHE PHE B . n 
B 2 234 GLU 234 234 234 GLU GLU B . n 
B 2 235 GLY 235 235 235 GLY GLY B . n 
B 2 236 THR 236 236 236 THR THR B . n 
B 2 237 LYS 237 237 237 LYS LYS B . n 
B 2 238 LEU 238 238 238 LEU LEU B . n 
B 2 239 ASP 239 239 239 ASP ASP B . n 
B 2 240 VAL 240 240 240 VAL VAL B . n 
B 2 241 GLY 241 241 241 GLY GLY B . n 
B 2 242 ASN 242 242 242 ASN ASN B . n 
B 2 243 ILE 243 243 243 ILE ILE B . n 
B 2 244 VAL 244 244 244 VAL VAL B . n 
B 2 245 LEU 245 245 245 LEU LEU B . n 
B 2 246 ALA 246 246 246 ALA ALA B . n 
B 2 247 LEU 247 247 247 LEU LEU B . n 
B 2 248 TYR 248 248 248 TYR TYR B . n 
B 2 249 SER 249 249 249 SER SER B . n 
B 2 250 GLY 250 250 250 GLY GLY B . n 
B 2 251 LEU 251 251 251 LEU LEU B . n 
B 2 252 PHE 252 252 252 PHE PHE B . n 
B 2 253 ALA 253 253 253 ALA ALA B . n 
B 2 254 TYR 254 254 254 TYR TYR B . n 
B 2 255 GLY 255 255 255 GLY GLY B . n 
B 2 256 GLY 256 256 256 GLY GLY B . n 
B 2 257 TRP 257 257 257 TRP TRP B . n 
B 2 258 ASN 258 258 258 ASN ASN B . n 
B 2 259 TYR 259 259 259 TYR TYR B . n 
B 2 260 LEU 260 260 260 LEU LEU B . n 
B 2 261 ASN 261 261 261 ASN ASN B . n 
B 2 262 PHE 262 262 262 PHE PHE B . n 
B 2 263 VAL 263 263 263 VAL VAL B . n 
B 2 264 THR 264 264 264 THR THR B . n 
B 2 265 GLU 265 265 265 GLU GLU B . n 
B 2 266 GLU 266 266 266 GLU GLU B . n 
B 2 267 MET 267 267 267 MET MET B . n 
B 2 268 ILE 268 268 268 ILE ILE B . n 
B 2 269 ASN 269 269 269 ASN ASN B . n 
B 2 270 PRO 270 270 270 PRO PRO B . n 
B 2 271 TYR 271 271 271 TYR TYR B . n 
B 2 272 ARG 272 272 272 ARG ARG B . n 
B 2 273 ASN 273 273 273 ASN ASN B . n 
B 2 274 LEU 274 274 274 LEU LEU B . n 
B 2 275 PRO 275 275 275 PRO PRO B . n 
B 2 276 LEU 276 276 276 LEU LEU B . n 
B 2 277 ALA 277 277 277 ALA ALA B . n 
B 2 278 ILE 278 278 278 ILE ILE B . n 
B 2 279 ILE 279 279 279 ILE ILE B . n 
B 2 280 ILE 280 280 280 ILE ILE B . n 
B 2 281 SER 281 281 281 SER SER B . n 
B 2 282 LEU 282 282 282 LEU LEU B . n 
B 2 283 PRO 283 283 283 PRO PRO B . n 
B 2 284 ILE 284 284 284 ILE ILE B . n 
B 2 285 VAL 285 285 285 VAL VAL B . n 
B 2 286 THR 286 286 286 THR THR B . n 
B 2 287 LEU 287 287 287 LEU LEU B . n 
B 2 288 VAL 288 288 288 VAL VAL B . n 
B 2 289 TYR 289 289 289 TYR TYR B . n 
B 2 290 VAL 290 290 290 VAL VAL B . n 
B 2 291 LEU 291 291 291 LEU LEU B . n 
B 2 292 THR 292 292 292 THR THR B . n 
B 2 293 ASN 293 293 293 ASN ASN B . n 
B 2 294 LEU 294 294 294 LEU LEU B . n 
B 2 295 ALA 295 295 295 ALA ALA B . n 
B 2 296 TYR 296 296 296 TYR TYR B . n 
B 2 297 PHE 297 297 297 PHE PHE B . n 
B 2 298 THR 298 298 298 THR THR B . n 
B 2 299 THR 299 299 299 THR THR B . n 
B 2 300 LEU 300 300 300 LEU LEU B . n 
B 2 301 SER 301 301 301 SER SER B . n 
B 2 302 THR 302 302 302 THR THR B . n 
B 2 303 GLU 303 303 303 GLU GLU B . n 
B 2 304 GLN 304 304 304 GLN GLN B . n 
B 2 305 MET 305 305 305 MET MET B . n 
B 2 306 LEU 306 306 306 LEU LEU B . n 
B 2 307 SER 307 307 307 SER SER B . n 
B 2 308 SER 308 308 308 SER SER B . n 
B 2 309 GLU 309 309 309 GLU GLU B . n 
B 2 310 ALA 310 310 310 ALA ALA B . n 
B 2 311 VAL 311 311 311 VAL VAL B . n 
B 2 312 ALA 312 312 312 ALA ALA B . n 
B 2 313 VAL 313 313 313 VAL VAL B . n 
B 2 314 ASP 314 314 314 ASP ASP B . n 
B 2 315 PHE 315 315 315 PHE PHE B . n 
B 2 316 GLY 316 316 316 GLY GLY B . n 
B 2 317 ASN 317 317 317 ASN ASN B . n 
B 2 318 TYR 318 318 318 TYR TYR B . n 
B 2 319 HIS 319 319 319 HIS HIS B . n 
B 2 320 LEU 320 320 320 LEU LEU B . n 
B 2 321 GLY 321 321 321 GLY GLY B . n 
B 2 322 VAL 322 322 322 VAL VAL B . n 
B 2 323 MET 323 323 323 MET MET B . n 
B 2 324 SER 324 324 324 SER SER B . n 
B 2 325 TRP 325 325 325 TRP TRP B . n 
B 2 326 ILE 326 326 326 ILE ILE B . n 
B 2 327 ILE 327 327 327 ILE ILE B . n 
B 2 328 PRO 328 328 328 PRO PRO B . n 
B 2 329 VAL 329 329 329 VAL VAL B . n 
B 2 330 PHE 330 330 330 PHE PHE B . n 
B 2 331 VAL 331 331 331 VAL VAL B . n 
B 2 332 GLY 332 332 332 GLY GLY B . n 
B 2 333 LEU 333 333 333 LEU LEU B . n 
B 2 334 SER 334 334 334 SER SER B . n 
B 2 335 CYS 335 335 335 CYS CYS B . n 
B 2 336 PHE 336 336 336 PHE PHE B . n 
B 2 337 GLY 337 337 337 GLY GLY B . n 
B 2 338 SER 338 338 338 SER SER B . n 
B 2 339 VAL 339 339 339 VAL VAL B . n 
B 2 340 ASN 340 340 340 ASN ASN B . n 
B 2 341 GLY 341 341 341 GLY GLY B . n 
B 2 342 SER 342 342 342 SER SER B . n 
B 2 343 LEU 343 343 343 LEU LEU B . n 
B 2 344 PHE 344 344 344 PHE PHE B . n 
B 2 345 THR 345 345 345 THR THR B . n 
B 2 346 SER 346 346 346 SER SER B . n 
B 2 347 SER 347 347 347 SER SER B . n 
B 2 348 ARG 348 348 348 ARG ARG B . n 
B 2 349 LEU 349 349 349 LEU LEU B . n 
B 2 350 PHE 350 350 350 PHE PHE B . n 
B 2 351 PHE 351 351 351 PHE PHE B . n 
B 2 352 VAL 352 352 352 VAL VAL B . n 
B 2 353 GLY 353 353 353 GLY GLY B . n 
B 2 354 SER 354 354 354 SER SER B . n 
B 2 355 ARG 355 355 355 ARG ARG B . n 
B 2 356 GLU 356 356 356 GLU GLU B . n 
B 2 357 GLY 357 357 357 GLY GLY B . n 
B 2 358 HIS 358 358 358 HIS HIS B . n 
B 2 359 LEU 359 359 359 LEU LEU B . n 
B 2 360 PRO 360 360 360 PRO PRO B . n 
B 2 361 SER 361 361 361 SER SER B . n 
B 2 362 ILE 362 362 362 ILE ILE B . n 
B 2 363 LEU 363 363 363 LEU LEU B . n 
B 2 364 SER 364 364 364 SER SER B . n 
B 2 365 MET 365 365 365 MET MET B . n 
B 2 366 ILE 366 366 366 ILE ILE B . n 
B 2 367 HIS 367 367 367 HIS HIS B . n 
B 2 368 PRO 368 368 368 PRO PRO B . n 
B 2 369 GLN 369 369 369 GLN GLN B . n 
B 2 370 LEU 370 370 370 LEU LEU B . n 
B 2 371 LEU 371 371 371 LEU LEU B . n 
B 2 372 THR 372 372 372 THR THR B . n 
B 2 373 PRO 373 373 373 PRO PRO B . n 
B 2 374 VAL 374 374 374 VAL VAL B . n 
B 2 375 PRO 375 375 375 PRO PRO B . n 
B 2 376 SER 376 376 376 SER SER B . n 
B 2 377 LEU 377 377 377 LEU LEU B . n 
B 2 378 VAL 378 378 378 VAL VAL B . n 
B 2 379 PHE 379 379 379 PHE PHE B . n 
B 2 380 THR 380 380 380 THR THR B . n 
B 2 381 CYS 381 381 381 CYS CYS B . n 
B 2 382 VAL 382 382 382 VAL VAL B . n 
B 2 383 MET 383 383 383 MET MET B . n 
B 2 384 THR 384 384 384 THR THR B . n 
B 2 385 LEU 385 385 385 LEU LEU B . n 
B 2 386 LEU 386 386 386 LEU LEU B . n 
B 2 387 TYR 387 387 387 TYR TYR B . n 
B 2 388 ALA 388 388 388 ALA ALA B . n 
B 2 389 PHE 389 389 389 PHE PHE B . n 
B 2 390 SER 390 390 390 SER SER B . n 
B 2 391 LYS 391 391 391 LYS LYS B . n 
B 2 392 ASP 392 392 392 ASP ASP B . n 
B 2 393 ILE 393 393 393 ILE ILE B . n 
B 2 394 PHE 394 394 394 PHE PHE B . n 
B 2 395 SER 395 395 395 SER SER B . n 
B 2 396 VAL 396 396 396 VAL VAL B . n 
B 2 397 ILE 397 397 397 ILE ILE B . n 
B 2 398 ASN 398 398 398 ASN ASN B . n 
B 2 399 PHE 399 399 399 PHE PHE B . n 
B 2 400 PHE 400 400 400 PHE PHE B . n 
B 2 401 SER 401 401 401 SER SER B . n 
B 2 402 PHE 402 402 402 PHE PHE B . n 
B 2 403 PHE 403 403 403 PHE PHE B . n 
B 2 404 ASN 404 404 404 ASN ASN B . n 
B 2 405 TRP 405 405 405 TRP TRP B . n 
B 2 406 LEU 406 406 406 LEU LEU B . n 
B 2 407 CYS 407 407 407 CYS CYS B . n 
B 2 408 VAL 408 408 408 VAL VAL B . n 
B 2 409 ALA 409 409 409 ALA ALA B . n 
B 2 410 LEU 410 410 410 LEU LEU B . n 
B 2 411 ALA 411 411 411 ALA ALA B . n 
B 2 412 ILE 412 412 412 ILE ILE B . n 
B 2 413 ILE 413 413 413 ILE ILE B . n 
B 2 414 GLY 414 414 414 GLY GLY B . n 
B 2 415 MET 415 415 415 MET MET B . n 
B 2 416 ILE 416 416 416 ILE ILE B . n 
B 2 417 TRP 417 417 417 TRP TRP B . n 
B 2 418 LEU 418 418 418 LEU LEU B . n 
B 2 419 ARG 419 419 419 ARG ARG B . n 
B 2 420 HIS 420 420 420 HIS HIS B . n 
B 2 421 ARG 421 421 421 ARG ARG B . n 
B 2 422 LYS 422 422 422 LYS LYS B . n 
B 2 423 PRO 423 423 423 PRO PRO B . n 
B 2 424 GLU 424 424 424 GLU GLU B . n 
B 2 425 LEU 425 425 425 LEU LEU B . n 
B 2 426 GLU 426 426 426 GLU GLU B . n 
B 2 427 ARG 427 427 427 ARG ARG B . n 
B 2 428 PRO 428 428 428 PRO PRO B . n 
B 2 429 ILE 429 429 429 ILE ILE B . n 
B 2 430 LYS 430 430 430 LYS LYS B . n 
B 2 431 VAL 431 431 431 VAL VAL B . n 
B 2 432 ASN 432 432 432 ASN ASN B . n 
B 2 433 LEU 433 433 433 LEU LEU B . n 
B 2 434 ALA 434 434 434 ALA ALA B . n 
B 2 435 LEU 435 435 435 LEU LEU B . n 
B 2 436 PRO 436 436 436 PRO PRO B . n 
B 2 437 VAL 437 437 437 VAL VAL B . n 
B 2 438 PHE 438 438 438 PHE PHE B . n 
B 2 439 PHE 439 439 439 PHE PHE B . n 
B 2 440 ILE 440 440 440 ILE ILE B . n 
B 2 441 LEU 441 441 441 LEU LEU B . n 
B 2 442 ALA 442 442 442 ALA ALA B . n 
B 2 443 CYS 443 443 443 CYS CYS B . n 
B 2 444 LEU 444 444 444 LEU LEU B . n 
B 2 445 PHE 445 445 445 PHE PHE B . n 
B 2 446 LEU 446 446 446 LEU LEU B . n 
B 2 447 ILE 447 447 447 ILE ILE B . n 
B 2 448 ALA 448 448 448 ALA ALA B . n 
B 2 449 VAL 449 449 449 VAL VAL B . n 
B 2 450 SER 450 450 450 SER SER B . n 
B 2 451 PHE 451 451 451 PHE PHE B . n 
B 2 452 TRP 452 452 452 TRP TRP B . n 
B 2 453 LYS 453 453 453 LYS LYS B . n 
B 2 454 THR 454 454 454 THR THR B . n 
B 2 455 PRO 455 455 455 PRO PRO B . n 
B 2 456 VAL 456 456 456 VAL VAL B . n 
B 2 457 GLU 457 457 457 GLU GLU B . n 
B 2 458 CYS 458 458 458 CYS CYS B . n 
B 2 459 GLY 459 459 459 GLY GLY B . n 
B 2 460 ILE 460 460 460 ILE ILE B . n 
B 2 461 GLY 461 461 461 GLY GLY B . n 
B 2 462 PHE 462 462 462 PHE PHE B . n 
B 2 463 THR 463 463 463 THR THR B . n 
B 2 464 ILE 464 464 464 ILE ILE B . n 
B 2 465 ILE 465 465 465 ILE ILE B . n 
B 2 466 LEU 466 466 466 LEU LEU B . n 
B 2 467 SER 467 467 467 SER SER B . n 
B 2 468 GLY 468 468 468 GLY GLY B . n 
B 2 469 LEU 469 469 469 LEU LEU B . n 
B 2 470 PRO 470 470 470 PRO PRO B . n 
B 2 471 VAL 471 471 471 VAL VAL B . n 
B 2 472 TYR 472 472 472 TYR TYR B . n 
B 2 473 PHE 473 473 473 PHE PHE B . n 
B 2 474 PHE 474 474 474 PHE PHE B . n 
B 2 475 GLY 475 475 475 GLY GLY B . n 
B 2 476 VAL 476 476 476 VAL VAL B . n 
B 2 477 TRP 477 477 477 TRP TRP B . n 
B 2 478 TRP 478 478 478 TRP TRP B . n 
B 2 479 LYS 479 479 479 LYS LYS B . n 
B 2 480 ASN 480 480 480 ASN ASN B . n 
B 2 481 LYS 481 481 481 LYS LYS B . n 
B 2 482 PRO 482 482 482 PRO PRO B . n 
B 2 483 LYS 483 483 483 LYS LYS B . n 
B 2 484 TRP 484 484 484 TRP TRP B . n 
B 2 485 LEU 485 485 485 LEU LEU B . n 
B 2 486 LEU 486 486 486 LEU LEU B . n 
B 2 487 GLN 487 487 487 GLN GLN B . n 
B 2 488 GLY 488 488 488 GLY GLY B . n 
B 2 489 ILE 489 489 489 ILE ILE B . n 
B 2 490 PHE 490 490 490 PHE PHE B . n 
B 2 491 SER 491 491 491 SER SER B . n 
B 2 492 THR 492 492 492 THR THR B . n 
B 2 493 THR 493 493 493 THR THR B . n 
B 2 494 VAL 494 494 494 VAL VAL B . n 
B 2 495 LEU 495 495 495 LEU LEU B . n 
B 2 496 CYS 496 496 496 CYS CYS B . n 
B 2 497 GLN 497 497 497 GLN GLN B . n 
B 2 498 LYS 498 498 498 LYS LYS B . n 
B 2 499 LEU 499 499 499 LEU LEU B . n 
B 2 500 MET 500 500 500 MET MET B . n 
B 2 501 GLN 501 501 501 GLN GLN B . n 
B 2 502 VAL 502 502 502 VAL VAL B . n 
B 2 503 VAL 503 503 503 VAL VAL B . n 
B 2 504 PRO 504 504 504 PRO PRO B . n 
B 2 505 GLN 505 505 505 GLN GLN B . n 
B 2 506 GLU 506 506 506 GLU GLU B . n 
B 2 507 THR 507 507 507 THR THR B . n 
B 2 508 ASP 508 508 ?   ?   ?   B . n 
B 2 509 TYR 509 509 ?   ?   ?   B . n 
B 2 510 LYS 510 510 ?   ?   ?   B . n 
B 2 511 ASP 511 511 ?   ?   ?   B . n 
B 2 512 ASP 512 512 ?   ?   ?   B . n 
B 2 513 ASP 513 513 ?   ?   ?   B . n 
B 2 514 ASP 514 514 ?   ?   ?   B . n 
B 2 515 LYS 515 515 ?   ?   ?   B . n 
C 3 1   ASP 1   1   1   ASP ASP L . n 
C 3 2   ILE 2   2   2   ILE ILE L . n 
C 3 3   VAL 3   3   3   VAL VAL L . n 
C 3 4   LEU 4   4   4   LEU LEU L . n 
C 3 5   THR 5   5   5   THR THR L . n 
C 3 6   GLN 6   6   6   GLN GLN L . n 
C 3 7   SER 7   7   7   SER SER L . n 
C 3 8   PRO 8   8   8   PRO PRO L . n 
C 3 9   SER 9   9   9   SER SER L . n 
C 3 10  SER 10  10  10  SER SER L . n 
C 3 11  LEU 11  11  11  LEU LEU L . n 
C 3 12  ALA 12  12  12  ALA ALA L . n 
C 3 13  MET 13  13  13  MET MET L . n 
C 3 14  SER 14  14  14  SER SER L . n 
C 3 15  VAL 15  15  15  VAL VAL L . n 
C 3 16  GLY 16  16  16  GLY GLY L . n 
C 3 17  GLN 17  17  17  GLN GLN L . n 
C 3 18  LYS 18  18  18  LYS LYS L . n 
C 3 19  VAL 19  19  19  VAL VAL L . n 
C 3 20  THR 20  20  20  THR THR L . n 
C 3 21  MET 21  21  21  MET MET L . n 
C 3 22  ASN 22  22  22  ASN ASN L . n 
C 3 23  CYS 23  23  23  CYS CYS L . n 
C 3 24  LYS 24  24  24  LYS LYS L . n 
C 3 25  SER 25  25  25  SER SER L . n 
C 3 26  SER 26  26  26  SER SER L . n 
C 3 27  GLN 27  27  27  GLN GLN L . n 
C 3 28  SER 28  28  28  SER SER L . n 
C 3 29  LEU 29  29  29  LEU LEU L . n 
C 3 30  LEU 30  30  30  LEU LEU L . n 
C 3 31  ASN 31  31  31  ASN ASN L . n 
C 3 32  ASN 32  32  32  ASN ASN L . n 
C 3 33  ASN 33  33  33  ASN ASN L . n 
C 3 34  ASN 34  34  34  ASN ASN L . n 
C 3 35  GLN 35  35  35  GLN GLN L . n 
C 3 36  LYS 36  36  36  LYS LYS L . n 
C 3 37  ASN 37  37  37  ASN ASN L . n 
C 3 38  TYR 38  38  38  TYR TYR L . n 
C 3 39  LEU 39  39  39  LEU LEU L . n 
C 3 40  ALA 40  40  40  ALA ALA L . n 
C 3 41  TRP 41  41  41  TRP TRP L . n 
C 3 42  TYR 42  42  42  TYR TYR L . n 
C 3 43  GLN 43  43  43  GLN GLN L . n 
C 3 44  GLN 44  44  44  GLN GLN L . n 
C 3 45  LYS 45  45  45  LYS LYS L . n 
C 3 46  PRO 46  46  46  PRO PRO L . n 
C 3 47  GLY 47  47  47  GLY GLY L . n 
C 3 48  GLN 48  48  48  GLN GLN L . n 
C 3 49  SER 49  49  49  SER SER L . n 
C 3 50  PRO 50  50  50  PRO PRO L . n 
C 3 51  LYS 51  51  51  LYS LYS L . n 
C 3 52  LEU 52  52  52  LEU LEU L . n 
C 3 53  LEU 53  53  53  LEU LEU L . n 
C 3 54  VAL 54  54  54  VAL VAL L . n 
C 3 55  TYR 55  55  55  TYR TYR L . n 
C 3 56  PHE 56  56  56  PHE PHE L . n 
C 3 57  THR 57  57  57  THR THR L . n 
C 3 58  SER 58  58  58  SER SER L . n 
C 3 59  THR 59  59  59  THR THR L . n 
C 3 60  ARG 60  60  60  ARG ARG L . n 
C 3 61  GLU 61  61  61  GLU GLU L . n 
C 3 62  SER 62  62  62  SER SER L . n 
C 3 63  GLY 63  63  63  GLY GLY L . n 
C 3 64  VAL 64  64  64  VAL VAL L . n 
C 3 65  PRO 65  65  65  PRO PRO L . n 
C 3 66  ASP 66  66  66  ASP ASP L . n 
C 3 67  ARG 67  67  67  ARG ARG L . n 
C 3 68  PHE 68  68  68  PHE PHE L . n 
C 3 69  ILE 69  69  69  ILE ILE L . n 
C 3 70  GLY 70  70  70  GLY GLY L . n 
C 3 71  SER 71  71  71  SER SER L . n 
C 3 72  GLY 72  72  72  GLY GLY L . n 
C 3 73  SER 73  73  73  SER SER L . n 
C 3 74  GLY 74  74  74  GLY GLY L . n 
C 3 75  THR 75  75  75  THR THR L . n 
C 3 76  ASP 76  76  76  ASP ASP L . n 
C 3 77  PHE 77  77  77  PHE PHE L . n 
C 3 78  THR 78  78  78  THR THR L . n 
C 3 79  LEU 79  79  79  LEU LEU L . n 
C 3 80  THR 80  80  80  THR THR L . n 
C 3 81  ILE 81  81  81  ILE ILE L . n 
C 3 82  SER 82  82  82  SER SER L . n 
C 3 83  SER 83  83  83  SER SER L . n 
C 3 84  VAL 84  84  84  VAL VAL L . n 
C 3 85  GLN 85  85  85  GLN GLN L . n 
C 3 86  ALA 86  86  86  ALA ALA L . n 
C 3 87  GLU 87  87  87  GLU GLU L . n 
C 3 88  ASP 88  88  88  ASP ASP L . n 
C 3 89  LEU 89  89  89  LEU LEU L . n 
C 3 90  ALA 90  90  90  ALA ALA L . n 
C 3 91  LEU 91  91  91  LEU LEU L . n 
C 3 92  TYR 92  92  92  TYR TYR L . n 
C 3 93  TYR 93  93  93  TYR TYR L . n 
C 3 94  CYS 94  94  94  CYS CYS L . n 
C 3 95  GLN 95  95  95  GLN GLN L . n 
C 3 96  GLN 96  96  96  GLN GLN L . n 
C 3 97  HIS 97  97  97  HIS HIS L . n 
C 3 98  TYR 98  98  98  TYR TYR L . n 
C 3 99  THR 99  99  99  THR THR L . n 
C 3 100 ILE 100 100 100 ILE ILE L . n 
C 3 101 PRO 101 101 101 PRO PRO L . n 
C 3 102 PRO 102 102 102 PRO PRO L . n 
C 3 103 THR 103 103 103 THR THR L . n 
C 3 104 PHE 104 104 104 PHE PHE L . n 
C 3 105 GLY 105 105 105 GLY GLY L . n 
C 3 106 GLY 106 106 106 GLY GLY L . n 
C 3 107 GLY 107 107 107 GLY GLY L . n 
C 3 108 THR 108 108 108 THR THR L . n 
C 3 109 LYS 109 109 109 LYS LYS L . n 
C 3 110 LEU 110 110 110 LEU LEU L . n 
C 3 111 GLU 111 111 111 GLU GLU L . n 
C 3 112 ILE 112 112 112 ILE ILE L . n 
C 3 113 LYS 113 113 113 LYS LYS L . n 
C 3 114 ARG 114 114 114 ARG ARG L . n 
C 3 115 ALA 115 115 115 ALA ALA L . n 
C 3 116 ASP 116 116 116 ASP ASP L . n 
C 3 117 ALA 117 117 117 ALA ALA L . n 
C 3 118 ALA 118 118 118 ALA ALA L . n 
C 3 119 PRO 119 119 119 PRO PRO L . n 
C 3 120 THR 120 120 120 THR THR L . n 
C 3 121 VAL 121 121 121 VAL VAL L . n 
C 3 122 SER 122 122 122 SER SER L . n 
C 3 123 ILE 123 123 123 ILE ILE L . n 
C 3 124 PHE 124 124 124 PHE PHE L . n 
C 3 125 PRO 125 125 125 PRO PRO L . n 
C 3 126 PRO 126 126 126 PRO PRO L . n 
C 3 127 SER 127 127 127 SER SER L . n 
C 3 128 SER 128 128 128 SER SER L . n 
C 3 129 GLU 129 129 129 GLU GLU L . n 
C 3 130 GLN 130 130 130 GLN GLN L . n 
C 3 131 LEU 131 131 131 LEU LEU L . n 
C 3 132 THR 132 132 132 THR THR L . n 
C 3 133 SER 133 133 133 SER SER L . n 
C 3 134 GLY 134 134 134 GLY GLY L . n 
C 3 135 GLY 135 135 135 GLY GLY L . n 
C 3 136 ALA 136 136 136 ALA ALA L . n 
C 3 137 SER 137 137 137 SER SER L . n 
C 3 138 VAL 138 138 138 VAL VAL L . n 
C 3 139 VAL 139 139 139 VAL VAL L . n 
C 3 140 CYS 140 140 140 CYS CYS L . n 
C 3 141 PHE 141 141 141 PHE PHE L . n 
C 3 142 LEU 142 142 142 LEU LEU L . n 
C 3 143 ASN 143 143 143 ASN ASN L . n 
C 3 144 ASN 144 144 144 ASN ASN L . n 
C 3 145 PHE 145 145 145 PHE PHE L . n 
C 3 146 TYR 146 146 146 TYR TYR L . n 
C 3 147 PRO 147 147 147 PRO PRO L . n 
C 3 148 LYS 148 148 148 LYS LYS L . n 
C 3 149 ASP 149 149 149 ASP ASP L . n 
C 3 150 ILE 150 150 150 ILE ILE L . n 
C 3 151 ASN 151 151 151 ASN ASN L . n 
C 3 152 VAL 152 152 152 VAL VAL L . n 
C 3 153 LYS 153 153 153 LYS LYS L . n 
C 3 154 TRP 154 154 154 TRP TRP L . n 
C 3 155 LYS 155 155 155 LYS LYS L . n 
C 3 156 ILE 156 156 156 ILE ILE L . n 
C 3 157 ASP 157 157 157 ASP ASP L . n 
C 3 158 GLY 158 158 158 GLY GLY L . n 
C 3 159 SER 159 159 159 SER SER L . n 
C 3 160 GLU 160 160 160 GLU GLU L . n 
C 3 161 ARG 161 161 161 ARG ARG L . n 
C 3 162 GLN 162 162 162 GLN GLN L . n 
C 3 163 ASN 163 163 163 ASN ASN L . n 
C 3 164 GLY 164 164 164 GLY GLY L . n 
C 3 165 VAL 165 165 165 VAL VAL L . n 
C 3 166 LEU 166 166 166 LEU LEU L . n 
C 3 167 ASN 167 167 167 ASN ASN L . n 
C 3 168 SER 168 168 168 SER SER L . n 
C 3 169 TRP 169 169 169 TRP TRP L . n 
C 3 170 THR 170 170 170 THR THR L . n 
C 3 171 ASP 171 171 171 ASP ASP L . n 
C 3 172 GLN 172 172 172 GLN GLN L . n 
C 3 173 ASP 173 173 173 ASP ASP L . n 
C 3 174 SER 174 174 174 SER SER L . n 
C 3 175 LYS 175 175 175 LYS LYS L . n 
C 3 176 ASP 176 176 176 ASP ASP L . n 
C 3 177 SER 177 177 177 SER SER L . n 
C 3 178 THR 178 178 178 THR THR L . n 
C 3 179 TYR 179 179 179 TYR TYR L . n 
C 3 180 SER 180 180 180 SER SER L . n 
C 3 181 MET 181 181 181 MET MET L . n 
C 3 182 SER 182 182 182 SER SER L . n 
C 3 183 SER 183 183 183 SER SER L . n 
C 3 184 THR 184 184 184 THR THR L . n 
C 3 185 LEU 185 185 185 LEU LEU L . n 
C 3 186 THR 186 186 186 THR THR L . n 
C 3 187 LEU 187 187 187 LEU LEU L . n 
C 3 188 THR 188 188 188 THR THR L . n 
C 3 189 LYS 189 189 189 LYS LYS L . n 
C 3 190 ASP 190 190 190 ASP ASP L . n 
C 3 191 GLU 191 191 191 GLU GLU L . n 
C 3 192 TYR 192 192 192 TYR TYR L . n 
C 3 193 GLU 193 193 193 GLU GLU L . n 
C 3 194 ARG 194 194 194 ARG ARG L . n 
C 3 195 HIS 195 195 195 HIS HIS L . n 
C 3 196 ASN 196 196 196 ASN ASN L . n 
C 3 197 SER 197 197 197 SER SER L . n 
C 3 198 TYR 198 198 198 TYR TYR L . n 
C 3 199 THR 199 199 199 THR THR L . n 
C 3 200 CYS 200 200 200 CYS CYS L . n 
C 3 201 GLU 201 201 201 GLU GLU L . n 
C 3 202 ALA 202 202 202 ALA ALA L . n 
C 3 203 THR 203 203 203 THR THR L . n 
C 3 204 HIS 204 204 204 HIS HIS L . n 
C 3 205 LYS 205 205 205 LYS LYS L . n 
C 3 206 THR 206 206 206 THR THR L . n 
C 3 207 SER 207 207 207 SER SER L . n 
C 3 208 THR 208 208 208 THR THR L . n 
C 3 209 SER 209 209 209 SER SER L . n 
C 3 210 PRO 210 210 210 PRO PRO L . n 
C 3 211 ILE 211 211 211 ILE ILE L . n 
C 3 212 VAL 212 212 212 VAL VAL L . n 
C 3 213 LYS 213 213 213 LYS LYS L . n 
C 3 214 SER 214 214 214 SER SER L . n 
C 3 215 PHE 215 215 215 PHE PHE L . n 
C 3 216 ASN 216 216 216 ASN ASN L . n 
C 3 217 ARG 217 217 217 ARG ARG L . n 
C 3 218 ASN 218 218 ?   ?   ?   L . n 
C 3 219 GLU 219 219 ?   ?   ?   L . n 
C 3 220 CYS 220 220 ?   ?   ?   L . n 
D 4 1   GLU 1   1   1   GLU GLU H . n 
D 4 2   VAL 2   2   2   VAL VAL H . n 
D 4 3   GLN 3   3   3   GLN GLN H . n 
D 4 4   LEU 4   4   4   LEU LEU H . n 
D 4 5   GLN 5   5   5   GLN GLN H . n 
D 4 6   GLN 6   6   6   GLN GLN H . n 
D 4 7   SER 7   7   7   SER SER H . n 
D 4 8   GLY 8   8   8   GLY GLY H . n 
D 4 9   ALA 9   9   9   ALA ALA H . n 
D 4 10  GLU 10  10  10  GLU GLU H . n 
D 4 11  LEU 11  11  11  LEU LEU H . n 
D 4 12  VAL 12  12  12  VAL VAL H . n 
D 4 13  LYS 13  13  13  LYS LYS H . n 
D 4 14  PRO 14  14  14  PRO PRO H . n 
D 4 15  GLY 15  15  15  GLY GLY H . n 
D 4 16  ALA 16  16  16  ALA ALA H . n 
D 4 17  SER 17  17  17  SER SER H . n 
D 4 18  VAL 18  18  18  VAL VAL H . n 
D 4 19  ASN 19  19  19  ASN ASN H . n 
D 4 20  LEU 20  20  20  LEU LEU H . n 
D 4 21  SER 21  21  21  SER SER H . n 
D 4 22  CYS 22  22  22  CYS CYS H . n 
D 4 23  LYS 23  23  23  LYS LYS H . n 
D 4 24  ALA 24  24  24  ALA ALA H . n 
D 4 25  SER 25  25  25  SER SER H . n 
D 4 26  GLY 26  26  26  GLY GLY H . n 
D 4 27  TYR 27  27  27  TYR TYR H . n 
D 4 28  THR 28  28  28  THR THR H . n 
D 4 29  PHE 29  29  29  PHE PHE H . n 
D 4 30  THR 30  30  30  THR THR H . n 
D 4 31  ASN 31  31  31  ASN ASN H . n 
D 4 32  TYR 32  32  32  TYR TYR H . n 
D 4 33  TRP 33  33  33  TRP TRP H . n 
D 4 34  MET 34  34  34  MET MET H . n 
D 4 35  HIS 35  35  35  HIS HIS H . n 
D 4 36  TRP 36  36  36  TRP TRP H . n 
D 4 37  VAL 37  37  37  VAL VAL H . n 
D 4 38  ARG 38  38  38  ARG ARG H . n 
D 4 39  LEU 39  39  39  LEU LEU H . n 
D 4 40  ARG 40  40  40  ARG ARG H . n 
D 4 41  PRO 41  41  41  PRO PRO H . n 
D 4 42  GLY 42  42  42  GLY GLY H . n 
D 4 43  GLN 43  43  43  GLN GLN H . n 
D 4 44  GLY 44  44  44  GLY GLY H . n 
D 4 45  LEU 45  45  45  LEU LEU H . n 
D 4 46  GLU 46  46  46  GLU GLU H . n 
D 4 47  TRP 47  47  47  TRP TRP H . n 
D 4 48  ILE 48  48  48  ILE ILE H . n 
D 4 49  GLY 49  49  49  GLY GLY H . n 
D 4 50  GLU 50  50  50  GLU GLU H . n 
D 4 51  ILE 51  51  51  ILE ILE H . n 
D 4 52  ASP 52  52  52  ASP ASP H . n 
D 4 53  PRO 53  53  53  PRO PRO H . n 
D 4 54  SER 54  54  54  SER SER H . n 
D 4 55  ASP 55  55  55  ASP ASP H . n 
D 4 56  SER 56  56  56  SER SER H . n 
D 4 57  TYR 57  57  57  TYR TYR H . n 
D 4 58  SER 58  58  58  SER SER H . n 
D 4 59  TYR 59  59  59  TYR TYR H . n 
D 4 60  TYR 60  60  60  TYR TYR H . n 
D 4 61  SER 61  61  61  SER SER H . n 
D 4 62  GLN 62  62  62  GLN GLN H . n 
D 4 63  ASN 63  63  63  ASN ASN H . n 
D 4 64  PHE 64  64  64  PHE PHE H . n 
D 4 65  LYS 65  65  65  LYS LYS H . n 
D 4 66  GLY 66  66  66  GLY GLY H . n 
D 4 67  LYS 67  67  67  LYS LYS H . n 
D 4 68  ALA 68  68  68  ALA ALA H . n 
D 4 69  THR 69  69  69  THR THR H . n 
D 4 70  LEU 70  70  70  LEU LEU H . n 
D 4 71  THR 71  71  71  THR THR H . n 
D 4 72  VAL 72  72  72  VAL VAL H . n 
D 4 73  ASP 73  73  73  ASP ASP H . n 
D 4 74  GLN 74  74  74  GLN GLN H . n 
D 4 75  SER 75  75  75  SER SER H . n 
D 4 76  SER 76  76  76  SER SER H . n 
D 4 77  ASN 77  77  77  ASN ASN H . n 
D 4 78  THR 78  78  78  THR THR H . n 
D 4 79  ALA 79  79  79  ALA ALA H . n 
D 4 80  TYR 80  80  80  TYR TYR H . n 
D 4 81  LEU 81  81  81  LEU LEU H . n 
D 4 82  GLN 82  82  82  GLN GLN H . n 
D 4 83  LEU 83  83  83  LEU LEU H . n 
D 4 84  THR 84  84  84  THR THR H . n 
D 4 85  SER 85  85  85  SER SER H . n 
D 4 86  LEU 86  86  86  LEU LEU H . n 
D 4 87  THR 87  87  87  THR THR H . n 
D 4 88  SER 88  88  88  SER SER H . n 
D 4 89  GLU 89  89  89  GLU GLU H . n 
D 4 90  ASP 90  90  90  ASP ASP H . n 
D 4 91  SER 91  91  91  SER SER H . n 
D 4 92  ALA 92  92  92  ALA ALA H . n 
D 4 93  VAL 93  93  93  VAL VAL H . n 
D 4 94  TYR 94  94  94  TYR TYR H . n 
D 4 95  TYR 95  95  95  TYR TYR H . n 
D 4 96  CYS 96  96  96  CYS CYS H . n 
D 4 97  ALA 97  97  97  ALA ALA H . n 
D 4 98  ARG 98  98  98  ARG ARG H . n 
D 4 99  GLY 99  99  99  GLY GLY H . n 
D 4 100 ARG 100 100 100 ARG ARG H . n 
D 4 101 GLN 101 101 101 GLN GLN H . n 
D 4 102 THR 102 102 102 THR THR H . n 
D 4 103 TYR 103 103 103 TYR TYR H . n 
D 4 104 TYR 104 104 104 TYR TYR H . n 
D 4 105 PRO 105 105 105 PRO PRO H . n 
D 4 106 TRP 106 106 106 TRP TRP H . n 
D 4 107 PHE 107 107 107 PHE PHE H . n 
D 4 108 PRO 108 108 108 PRO PRO H . n 
D 4 109 TYR 109 109 109 TYR TYR H . n 
D 4 110 TRP 110 110 110 TRP TRP H . n 
D 4 111 GLY 111 111 111 GLY GLY H . n 
D 4 112 GLN 112 112 112 GLN GLN H . n 
D 4 113 GLY 113 113 113 GLY GLY H . n 
D 4 114 THR 114 114 114 THR THR H . n 
D 4 115 LEU 115 115 115 LEU LEU H . n 
D 4 116 VAL 116 116 116 VAL VAL H . n 
D 4 117 THR 117 117 117 THR THR H . n 
D 4 118 VAL 118 118 118 VAL VAL H . n 
D 4 119 SER 119 119 119 SER SER H . n 
D 4 120 ALA 120 120 120 ALA ALA H . n 
D 4 121 ALA 121 121 121 ALA ALA H . n 
D 4 122 LYS 122 122 122 LYS LYS H . n 
D 4 123 THR 123 123 123 THR THR H . n 
D 4 124 THR 124 124 124 THR THR H . n 
D 4 125 PRO 125 125 125 PRO PRO H . n 
D 4 126 PRO 126 126 126 PRO PRO H . n 
D 4 127 SER 127 127 127 SER SER H . n 
D 4 128 ASP 128 128 128 ASP ASP H . n 
D 4 129 TYR 129 129 129 TYR TYR H . n 
D 4 130 PRO 130 130 130 PRO PRO H . n 
D 4 131 LEU 131 131 131 LEU LEU H . n 
D 4 132 ALA 132 132 132 ALA ALA H . n 
D 4 133 PRO 133 133 133 PRO PRO H . n 
D 4 134 GLY 134 134 134 GLY GLY H . n 
D 4 135 SER 135 135 135 SER SER H . n 
D 4 136 ALA 136 136 136 ALA ALA H . n 
D 4 137 ALA 137 137 137 ALA ALA H . n 
D 4 138 GLN 138 138 138 GLN GLN H . n 
D 4 139 THR 139 139 139 THR THR H . n 
D 4 140 ASN 140 140 140 ASN ASN H . n 
D 4 141 SER 141 141 141 SER SER H . n 
D 4 142 MET 142 142 142 MET MET H . n 
D 4 143 VAL 143 143 143 VAL VAL H . n 
D 4 144 THR 144 144 144 THR THR H . n 
D 4 145 LEU 145 145 145 LEU LEU H . n 
D 4 146 GLY 146 146 146 GLY GLY H . n 
D 4 147 CYS 147 147 147 CYS CYS H . n 
D 4 148 LEU 148 148 148 LEU LEU H . n 
D 4 149 VAL 149 149 149 VAL VAL H . n 
D 4 150 LYS 150 150 150 LYS LYS H . n 
D 4 151 GLY 151 151 151 GLY GLY H . n 
D 4 152 TYR 152 152 152 TYR TYR H . n 
D 4 153 PHE 153 153 153 PHE PHE H . n 
D 4 154 PRO 154 154 154 PRO PRO H . n 
D 4 155 GLU 155 155 155 GLU GLU H . n 
D 4 156 PRO 156 156 156 PRO PRO H . n 
D 4 157 VAL 157 157 157 VAL VAL H . n 
D 4 158 THR 158 158 158 THR THR H . n 
D 4 159 VAL 159 159 159 VAL VAL H . n 
D 4 160 THR 160 160 160 THR THR H . n 
D 4 161 TRP 161 161 161 TRP TRP H . n 
D 4 162 ASN 162 162 162 ASN ASN H . n 
D 4 163 SER 163 163 163 SER SER H . n 
D 4 164 GLY 164 164 164 GLY GLY H . n 
D 4 165 SER 165 165 165 SER SER H . n 
D 4 166 LEU 166 166 166 LEU LEU H . n 
D 4 167 SER 167 167 167 SER SER H . n 
D 4 168 SER 168 168 168 SER SER H . n 
D 4 169 GLY 169 169 169 GLY GLY H . n 
D 4 170 VAL 170 170 170 VAL VAL H . n 
D 4 171 HIS 171 171 171 HIS HIS H . n 
D 4 172 THR 172 172 172 THR THR H . n 
D 4 173 PHE 173 173 173 PHE PHE H . n 
D 4 174 PRO 174 174 174 PRO PRO H . n 
D 4 175 ALA 175 175 175 ALA ALA H . n 
D 4 176 VAL 176 176 176 VAL VAL H . n 
D 4 177 LEU 177 177 177 LEU LEU H . n 
D 4 178 GLN 178 178 178 GLN GLN H . n 
D 4 179 SER 179 179 179 SER SER H . n 
D 4 180 ASP 180 180 180 ASP ASP H . n 
D 4 181 LEU 181 181 181 LEU LEU H . n 
D 4 182 TYR 182 182 182 TYR TYR H . n 
D 4 183 THR 183 183 183 THR THR H . n 
D 4 184 LEU 184 184 184 LEU LEU H . n 
D 4 185 SER 185 185 185 SER SER H . n 
D 4 186 SER 186 186 186 SER SER H . n 
D 4 187 SER 187 187 187 SER SER H . n 
D 4 188 VAL 188 188 188 VAL VAL H . n 
D 4 189 THR 189 189 189 THR THR H . n 
D 4 190 VAL 190 190 190 VAL VAL H . n 
D 4 191 PRO 191 191 191 PRO PRO H . n 
D 4 192 SER 192 192 192 SER SER H . n 
D 4 193 SER 193 193 193 SER SER H . n 
D 4 194 THR 194 194 194 THR THR H . n 
D 4 195 TRP 195 195 195 TRP TRP H . n 
D 4 196 PRO 196 196 196 PRO PRO H . n 
D 4 197 SER 197 197 197 SER SER H . n 
D 4 198 GLU 198 198 198 GLU GLU H . n 
D 4 199 THR 199 199 199 THR THR H . n 
D 4 200 VAL 200 200 200 VAL VAL H . n 
D 4 201 THR 201 201 201 THR THR H . n 
D 4 202 CYS 202 202 202 CYS CYS H . n 
D 4 203 ASN 203 203 203 ASN ASN H . n 
D 4 204 VAL 204 204 204 VAL VAL H . n 
D 4 205 ALA 205 205 205 ALA ALA H . n 
D 4 206 HIS 206 206 206 HIS HIS H . n 
D 4 207 PRO 207 207 207 PRO PRO H . n 
D 4 208 ALA 208 208 208 ALA ALA H . n 
D 4 209 SER 209 209 209 SER SER H . n 
D 4 210 SER 210 210 210 SER SER H . n 
D 4 211 THR 211 211 211 THR THR H . n 
D 4 212 LYS 212 212 212 LYS LYS H . n 
D 4 213 VAL 213 213 213 VAL VAL H . n 
D 4 214 ASP 214 214 214 ASP ASP H . n 
D 4 215 LYS 215 215 215 LYS LYS H . n 
D 4 216 LYS 216 216 216 LYS LYS H . n 
D 4 217 ILE 217 217 217 ILE ILE H . n 
D 4 218 VAL 218 218 218 VAL VAL H . n 
D 4 219 PRO 219 219 219 PRO PRO H . n 
D 4 220 ARG 220 220 220 ARG ARG H . n 
D 4 221 ASP 221 221 ?   ?   ?   H . n 
D 4 222 CYS 222 222 ?   ?   ?   H . n 
D 4 223 GLY 223 223 ?   ?   ?   H . n 
D 4 224 CYS 224 224 ?   ?   ?   H . n 
D 4 225 LYS 225 225 ?   ?   ?   H . n 
D 4 226 PRO 226 226 ?   ?   ?   H . n 
D 4 227 CYS 227 227 ?   ?   ?   H . n 
D 4 228 ILE 228 228 ?   ?   ?   H . n 
D 4 229 CYS 229 229 ?   ?   ?   H . n 
D 4 230 THR 230 230 ?   ?   ?   H . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        VU0 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   VU0 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 5 NAG 1 701 631 NAG NAG A . 
F 5 NAG 1 702 632 NAG NAG A . 
G 5 NAG 1 703 634 NAG NAG A . 
H 5 NAG 1 704 635 NAG NAG A . 
I 6 VU0 1 601 1   VU0 BCH B . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8KDG 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8KDG 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8KDG 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               213.527 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.945 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  'HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8KDG 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.68 
_refine.ls_d_res_low                             3.68 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     85744 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    100.00 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.26958 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.26958 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'PARAMETERS FOR MASK CACLULATION' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD WITH PHASES' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.480 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             12.132 
_refine.overall_SU_ML                            0.173 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'ELECTRON MICROSCOPY' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       . 
_refine_hist.d_res_low                        . 
_refine_hist.number_atoms_solvent             ? 
_refine_hist.number_atoms_total               10601 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        ? 
_refine_hist.pdbx_number_atoms_nucleic_acid   ? 
_refine_hist.pdbx_number_atoms_ligand         ? 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.012  0.012  10876 ? r_bond_refined_d             ? ? 
'ELECTRON MICROSCOPY' ? 0.000  0.016  10301 ? r_bond_other_d               ? ? 
'ELECTRON MICROSCOPY' ? 2.054  1.644  14834 ? r_angle_refined_deg          ? ? 
'ELECTRON MICROSCOPY' ? 0.728  1.567  23749 ? r_angle_other_deg            ? ? 
'ELECTRON MICROSCOPY' ? 8.646  5.000  1355  ? r_dihedral_angle_1_deg       ? ? 
'ELECTRON MICROSCOPY' ? 16.271 5.000  43    ? r_dihedral_angle_2_deg       ? ? 
'ELECTRON MICROSCOPY' ? 15.133 10.000 1751  ? r_dihedral_angle_3_deg       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_dihedral_angle_4_deg       ? ? 
'ELECTRON MICROSCOPY' ? 0.083  0.200  1714  ? r_chiral_restr               ? ? 
'ELECTRON MICROSCOPY' ? 0.004  0.020  12617 ? r_gen_planes_refined         ? ? 
'ELECTRON MICROSCOPY' ? 0.001  0.020  2465  ? r_gen_planes_other           ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'ELECTRON MICROSCOPY' ? 32.563 19.011 5435  ? r_mcbond_it                  ? ? 
'ELECTRON MICROSCOPY' ? 32.561 19.011 5435  ? r_mcbond_other               ? ? 
'ELECTRON MICROSCOPY' ? 46.474 34.306 6785  ? r_mcangle_it                 ? ? 
'ELECTRON MICROSCOPY' ? 46.471 34.309 6786  ? r_mcangle_other              ? ? 
'ELECTRON MICROSCOPY' ? 41.412 22.743 5441  ? r_scbond_it                  ? ? 
'ELECTRON MICROSCOPY' ? 41.405 22.744 5440  ? r_scbond_other               ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'ELECTRON MICROSCOPY' ? 63.294 40.050 8050  ? r_scangle_other              ? ? 
'ELECTRON MICROSCOPY' ? 68.616 232.86 43399 ? r_long_range_B_refined       ? ? 
'ELECTRON MICROSCOPY' ? 68.615 232.86 43400 ? r_long_range_B_other         ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'ELECTRON MICROSCOPY' 
_refine_ls_shell.d_res_high                       3.600 
_refine_ls_shell.d_res_low                        3.693 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             0 
_refine_ls_shell.number_reflns_R_work             6313 
_refine_ls_shell.percent_reflns_obs               100.00 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  1.869 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.000 
# 
_struct.entry_id                     8KDG 
_struct.title                        'Structure of LAT1-CD98hc-Fab170 in complex with BCH, consensus map' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8KDG 
_struct_keywords.text            'Transporter, Amino acid, Complex, Cancer, TRANSPORT PROTEIN' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 5 ? 
G N N 5 ? 
H N N 5 ? 
I N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP 4F2_HUMAN  P08195 ? 1 
;ELQPPEASIAVVSIPRQLPGSHSEAGVQGLSAGDDSELGSHCVAQTGLELLASGDPLPSASQNAEMIETGSDCVTQAGLQ
LLASSDPPALASKNAEVTGTMSQDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEKNGLVKIKVAEDEAEAAAAAKF
TGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAGNL
AGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWFST
QVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQILSLLESNKDLLLT
SSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAALPG
QPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQNE
RFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPYAA
;
2 
2 UNP LAT1_HUMAN Q01650 ? 2 
;MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAG
SPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPL
FPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV
GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHL
GVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFF
SFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN
KPKWLLQGIFSTTVLCQKLMQVVPQET
;
1 
3 PDB 8KDG       8KDG   ? 3 ? 1 
4 PDB 8KDG       8KDG   ? 4 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8KDG A 3 ? 631 ? P08195 2 ? 630 ? 2 630 
2 2 8KDG B 1 ? 507 ? Q01650 1 ? 507 ? 1 507 
3 3 8KDG L 1 ? 220 ? 8KDG   1 ? 220 ? 1 220 
4 4 8KDG H 1 ? 230 ? 8KDG   1 ? 230 ? 1 230 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8KDG GLY A 1   ? UNP P08195 ? ? 'expression tag' 0   1  
1 8KDG SER A 2   ? UNP P08195 ? ? 'expression tag' 1   2  
2 8KDG ASP B 508 ? UNP Q01650 ? ? 'expression tag' 508 3  
2 8KDG TYR B 509 ? UNP Q01650 ? ? 'expression tag' 509 4  
2 8KDG LYS B 510 ? UNP Q01650 ? ? 'expression tag' 510 5  
2 8KDG ASP B 511 ? UNP Q01650 ? ? 'expression tag' 511 6  
2 8KDG ASP B 512 ? UNP Q01650 ? ? 'expression tag' 512 7  
2 8KDG ASP B 513 ? UNP Q01650 ? ? 'expression tag' 513 8  
2 8KDG ASP B 514 ? UNP Q01650 ? ? 'expression tag' 514 9  
2 8KDG LYS B 515 ? UNP Q01650 ? ? 'expression tag' 515 10 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 166 ? GLY A 175 ? SER A 165 GLY A 174 1 ? 10 
HELX_P HELX_P2  AA2 SER A 176 ? ALA A 208 ? SER A 175 ALA A 207 1 ? 33 
HELX_P HELX_P3  AA3 LYS A 218 ? GLY A 223 ? LYS A 217 GLY A 222 5 ? 6  
HELX_P HELX_P4  AA4 ASN A 241 ? LYS A 256 ? ASN A 240 LYS A 255 1 ? 16 
HELX_P HELX_P5  AA5 ASP A 282 ? GLY A 286 ? ASP A 281 GLY A 285 5 ? 5  
HELX_P HELX_P6  AA6 SER A 287 ? SER A 302 ? SER A 286 SER A 301 1 ? 16 
HELX_P HELX_P7  AA7 GLN A 323 ? GLY A 342 ? GLN A 322 GLY A 341 1 ? 20 
HELX_P HELX_P8  AA8 ASP A 350 ? LEU A 354 ? ASP A 349 LEU A 353 5 ? 5  
HELX_P HELX_P9  AA9 ASP A 356 ? SER A 372 ? ASP A 355 SER A 371 1 ? 17 
HELX_P HELX_P10 AB1 ASP A 385 ? ASN A 396 ? ASP A 384 ASN A 395 1 ? 12 
HELX_P HELX_P11 AB2 HIS A 415 ? GLY A 428 ? HIS A 414 GLY A 427 1 ? 14 
HELX_P HELX_P12 AB3 LEU A 441 ? PHE A 445 ? LEU A 440 PHE A 444 5 ? 5  
HELX_P HELX_P13 AB4 LEU A 450 ? PHE A 459 ? LEU A 449 PHE A 458 1 ? 10 
HELX_P HELX_P14 AB5 GLY A 470 ? GLY A 474 ? GLY A 469 GLY A 473 5 ? 5  
HELX_P HELX_P15 AB6 SER A 505 ? MET A 508 ? SER A 504 MET A 507 5 ? 4  
HELX_P HELX_P16 AB7 THR A 509 ? GLU A 515 ? THR A 508 GLU A 514 1 ? 7  
HELX_P HELX_P17 AB8 SER A 519 ? GLU A 534 ? SER A 518 GLU A 533 1 ? 16 
HELX_P HELX_P18 AB9 GLU A 534 ? GLY A 540 ? GLU A 533 GLY A 539 1 ? 7  
HELX_P HELX_P19 AC1 PRO A 585 ? SER A 589 ? PRO A 584 SER A 588 5 ? 5  
HELX_P HELX_P20 AC2 GLU A 613 ? LEU A 615 ? GLU A 612 LEU A 614 5 ? 3  
HELX_P HELX_P21 AC3 THR B 51  ? GLY B 65  ? THR B 51  GLY B 65  1 ? 15 
HELX_P HELX_P22 AC4 SER B 66  ? THR B 71  ? SER B 66  THR B 71  1 ? 6  
HELX_P HELX_P23 AC5 THR B 71  ? GLY B 80  ? THR B 71  GLY B 80  1 ? 10 
HELX_P HELX_P24 AC6 SER B 81  ? SER B 111 ? SER B 81  SER B 111 1 ? 31 
HELX_P HELX_P25 AC7 GLY B 114 ? GLY B 125 ? GLY B 114 GLY B 125 1 ? 12 
HELX_P HELX_P26 AC8 GLY B 125 ? ILE B 139 ? GLY B 125 ILE B 139 1 ? 15 
HELX_P HELX_P27 AC9 ILE B 139 ? LYS B 158 ? ILE B 139 LYS B 158 1 ? 20 
HELX_P HELX_P28 AD1 PRO B 159 ? PHE B 161 ? PRO B 159 PHE B 161 5 ? 3  
HELX_P HELX_P29 AD2 PRO B 167 ? SER B 189 ? PRO B 167 SER B 189 1 ? 23 
HELX_P HELX_P30 AD3 SER B 189 ? GLY B 222 ? SER B 189 GLY B 222 1 ? 34 
HELX_P HELX_P31 AD4 ASP B 239 ? GLY B 255 ? ASP B 239 GLY B 255 1 ? 17 
HELX_P HELX_P32 AD5 TYR B 259 ? VAL B 263 ? TYR B 259 VAL B 263 5 ? 5  
HELX_P HELX_P33 AD6 ASN B 269 ? LEU B 300 ? ASN B 269 LEU B 300 1 ? 32 
HELX_P HELX_P34 AD7 SER B 301 ? SER B 308 ? SER B 301 SER B 308 1 ? 8  
HELX_P HELX_P35 AD8 ALA B 310 ? GLY B 321 ? ALA B 310 GLY B 321 1 ? 12 
HELX_P HELX_P36 AD9 VAL B 322 ? SER B 324 ? VAL B 322 SER B 324 5 ? 3  
HELX_P HELX_P37 AE1 TRP B 325 ? GLU B 356 ? TRP B 325 GLU B 356 1 ? 32 
HELX_P HELX_P38 AE2 PRO B 360 ? MET B 365 ? PRO B 360 MET B 365 5 ? 6  
HELX_P HELX_P39 AE3 PRO B 373 ? LEU B 386 ? PRO B 373 LEU B 386 1 ? 14 
HELX_P HELX_P40 AE4 TYR B 387 ? SER B 390 ? TYR B 387 SER B 390 5 ? 4  
HELX_P HELX_P41 AE5 ASP B 392 ? SER B 395 ? ASP B 392 SER B 395 5 ? 4  
HELX_P HELX_P42 AE6 VAL B 396 ? LYS B 422 ? VAL B 396 LYS B 422 1 ? 27 
HELX_P HELX_P43 AE7 LEU B 433 ? THR B 454 ? LEU B 433 THR B 454 1 ? 22 
HELX_P HELX_P44 AE8 THR B 454 ? SER B 467 ? THR B 454 SER B 467 1 ? 14 
HELX_P HELX_P45 AE9 SER B 467 ? VAL B 476 ? SER B 467 VAL B 476 1 ? 10 
HELX_P HELX_P46 AF1 PRO B 482 ? GLN B 501 ? PRO B 482 GLN B 501 1 ? 20 
HELX_P HELX_P47 AF2 GLN C 85  ? LEU C 89  ? GLN L 85  LEU L 89  5 ? 5  
HELX_P HELX_P48 AF3 GLU C 129 ? SER C 133 ? GLU L 129 SER L 133 5 ? 5  
HELX_P HELX_P49 AF4 LYS C 189 ? ARG C 194 ? LYS L 189 ARG L 194 1 ? 6  
HELX_P HELX_P50 AF5 THR D 28  ? TYR D 32  ? THR H 28  TYR H 32  5 ? 5  
HELX_P HELX_P51 AF6 GLN D 62  ? LYS D 65  ? GLN H 62  LYS H 65  5 ? 4  
HELX_P HELX_P52 AF7 THR D 87  ? SER D 91  ? THR H 87  SER H 91  5 ? 5  
HELX_P HELX_P53 AF8 ALA D 136 ? ASN D 140 ? ALA H 136 ASN H 140 5 ? 5  
HELX_P HELX_P54 AF9 THR D 194 ? GLU D 198 ? THR H 194 GLU H 198 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?   ? A CYS 211 SG  ? ? ? 1_555 B CYS 164 SG ? ? A CYS 210 B CYS 164 1_555 ? ? ? ? ? ? ? 2.111 ? ?               
disulf2 disulf ?   ? C CYS 23  SG  ? ? ? 1_555 C CYS 94  SG ? ? L CYS 23  L CYS 94  1_555 ? ? ? ? ? ? ? 2.160 ? ?               
disulf3 disulf ?   ? C CYS 140 SG  ? ? ? 1_555 C CYS 200 SG ? ? L CYS 140 L CYS 200 1_555 ? ? ? ? ? ? ? 2.051 ? ?               
disulf4 disulf ?   ? D CYS 22  SG  ? ? ? 1_555 D CYS 96  SG ? ? H CYS 22  H CYS 96  1_555 ? ? ? ? ? ? ? 2.064 ? ?               
disulf5 disulf ?   ? D CYS 147 SG  ? ? ? 1_555 D CYS 202 SG ? ? H CYS 147 H CYS 202 1_555 ? ? ? ? ? ? ? 2.069 ? ?               
covale1 covale one ? A ASN 366 ND2 ? ? ? 1_555 G NAG .   C1 ? ? A ASN 365 A NAG 703 1_555 ? ? ? ? ? ? ? 1.435 ? N-Glycosylation 
covale2 covale one ? A ASN 382 ND2 ? ? ? 1_555 E NAG .   C1 ? ? A ASN 381 A NAG 701 1_555 ? ? ? ? ? ? ? 1.453 ? N-Glycosylation 
covale3 covale one ? A ASN 425 ND2 ? ? ? 1_555 H NAG .   C1 ? ? A ASN 424 A NAG 704 1_555 ? ? ? ? ? ? ? 1.434 ? N-Glycosylation 
covale4 covale one ? A ASN 507 ND2 ? ? ? 1_555 F NAG .   C1 ? ? A ASN 506 A NAG 702 1_555 ? ? ? ? ? ? ? 1.463 ? N-Glycosylation 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 NAG E .   ? ASN A 382 ? NAG A 701 ? 1_555 ASN A 381 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2 NAG F .   ? ASN A 507 ? NAG A 702 ? 1_555 ASN A 506 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3 NAG G .   ? ASN A 366 ? NAG A 703 ? 1_555 ASN A 365 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4 NAG H .   ? ASN A 425 ? NAG A 704 ? 1_555 ASN A 424 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5 CYS A 211 ? CYS B 164 ? CYS A 210 ? 1_555 CYS B 164 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
6 CYS C 23  ? CYS C 94  ? CYS L 23  ? 1_555 CYS L 94  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
7 CYS C 140 ? CYS C 200 ? CYS L 140 ? 1_555 CYS L 200 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
8 CYS D 22  ? CYS D 96  ? CYS H 22  ? 1_555 CYS H 96  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
9 CYS D 147 ? CYS D 202 ? CYS H 147 ? 1_555 CYS H 202 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 SER 7   C . ? SER 7   L PRO 8   C ? PRO 8   L 1 -13.26 
2 ILE 100 C . ? ILE 100 L PRO 101 C ? PRO 101 L 1 2.54   
3 TYR 146 C . ? TYR 146 L PRO 147 C ? PRO 147 L 1 -5.20  
4 PHE 153 D . ? PHE 153 H PRO 154 D ? PRO 154 H 1 -8.66  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 6 ? 
AA3 ? 2 ? 
AA4 ? 4 ? 
AA5 ? 6 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 6 ? 
AB1 ? 4 ? 
AB2 ? 4 ? 
AB3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA1 6 7 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? parallel      
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AA9 5 6 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LEU A 400 ? THR A 402 ? LEU A 399 THR A 401 
AA1 2 LEU A 376 ? GLY A 380 ? LEU A 375 GLY A 379 
AA1 3 GLY A 345 ? VAL A 348 ? GLY A 344 VAL A 347 
AA1 4 ILE A 306 ? ASP A 308 ? ILE A 305 ASP A 307 
AA1 5 VAL A 261 ? LEU A 262 ? VAL A 260 LEU A 261 
AA1 6 LEU A 225 ? ILE A 228 ? LEU A 224 ILE A 227 
AA1 7 VAL A 466 ? SER A 468 ? VAL A 465 SER A 467 
AA2 1 ASP A 541 ? PHE A 545 ? ASP A 540 PHE A 544 
AA2 2 PHE A 552 ? HIS A 557 ? PHE A 551 HIS A 556 
AA2 3 ARG A 563 ? LEU A 568 ? ARG A 562 LEU A 567 
AA2 4 GLY A 622 ? PHE A 627 ? GLY A 621 PHE A 626 
AA2 5 LYS A 593 ? SER A 599 ? LYS A 592 SER A 598 
AA2 6 PRO A 609 ? GLU A 611 ? PRO A 608 GLU A 610 
AA3 1 GLY A 574 ? LEU A 575 ? GLY A 573 LEU A 574 
AA3 2 THR C 99  ? ILE C 100 ? THR L 99  ILE L 100 
AA4 1 LEU C 4   ? SER C 7   ? LEU L 4   SER L 7   
AA4 2 VAL C 19  ? SER C 25  ? VAL L 19  SER L 25  
AA4 3 ASP C 76  ? ILE C 81  ? ASP L 76  ILE L 81  
AA4 4 PHE C 68  ? SER C 73  ? PHE L 68  SER L 73  
AA5 1 SER C 10  ? SER C 14  ? SER L 10  SER L 14  
AA5 2 THR C 108 ? LYS C 113 ? THR L 108 LYS L 113 
AA5 3 ALA C 90  ? GLN C 96  ? ALA L 90  GLN L 96  
AA5 4 LEU C 39  ? GLN C 44  ? LEU L 39  GLN L 44  
AA5 5 LYS C 51  ? TYR C 55  ? LYS L 51  TYR L 55  
AA5 6 THR C 59  ? ARG C 60  ? THR L 59  ARG L 60  
AA6 1 THR C 120 ? PHE C 124 ? THR L 120 PHE L 124 
AA6 2 GLY C 135 ? PHE C 145 ? GLY L 135 PHE L 145 
AA6 3 TYR C 179 ? THR C 188 ? TYR L 179 THR L 188 
AA6 4 VAL C 165 ? TRP C 169 ? VAL L 165 TRP L 169 
AA7 1 SER C 159 ? ARG C 161 ? SER L 159 ARG L 161 
AA7 2 ASN C 151 ? ILE C 156 ? ASN L 151 ILE L 156 
AA7 3 SER C 197 ? THR C 203 ? SER L 197 THR L 203 
AA7 4 ILE C 211 ? ASN C 216 ? ILE L 211 ASN L 216 
AA8 1 GLN D 3   ? GLN D 6   ? GLN H 3   GLN H 6   
AA8 2 VAL D 18  ? SER D 25  ? VAL H 18  SER H 25  
AA8 3 THR D 78  ? LEU D 83  ? THR H 78  LEU H 83  
AA8 4 ALA D 68  ? ASP D 73  ? ALA H 68  ASP H 73  
AA9 1 ALA D 9   ? VAL D 12  ? ALA H 9   VAL H 12  
AA9 2 THR D 114 ? VAL D 118 ? THR H 114 VAL H 118 
AA9 3 ALA D 92  ? ARG D 98  ? ALA H 92  ARG H 98  
AA9 4 MET D 34  ? LEU D 39  ? MET H 34  LEU H 39  
AA9 5 LEU D 45  ? ILE D 51  ? LEU H 45  ILE H 51  
AA9 6 SER D 58  ? TYR D 60  ? SER H 58  TYR H 60  
AB1 1 ALA D 9   ? VAL D 12  ? ALA H 9   VAL H 12  
AB1 2 THR D 114 ? VAL D 118 ? THR H 114 VAL H 118 
AB1 3 ALA D 92  ? ARG D 98  ? ALA H 92  ARG H 98  
AB1 4 TYR D 109 ? TRP D 110 ? TYR H 109 TRP H 110 
AB2 1 SER D 127 ? LEU D 131 ? SER H 127 LEU H 131 
AB2 2 MET D 142 ? TYR D 152 ? MET H 142 TYR H 152 
AB2 3 LEU D 181 ? PRO D 191 ? LEU H 181 PRO H 191 
AB2 4 VAL D 170 ? GLN D 178 ? VAL H 170 GLN H 178 
AB3 1 THR D 201 ? ALA D 205 ? THR H 201 ALA H 205 
AB3 2 LYS D 212 ? LYS D 216 ? LYS H 212 LYS H 216 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O LEU A 400 ? O LEU A 399 N ALA A 379 ? N ALA A 378 
AA1 2 3 O ILE A 378 ? O ILE A 377 N PHE A 346 ? N PHE A 345 
AA1 3 4 O GLY A 345 ? O GLY A 344 N LEU A 307 ? N LEU A 306 
AA1 4 5 O ILE A 306 ? O ILE A 305 N LEU A 262 ? N LEU A 261 
AA1 5 6 O VAL A 261 ? O VAL A 260 N ILE A 228 ? N ILE A 227 
AA1 6 7 N ARG A 227 ? N ARG A 226 O PHE A 467 ? O PHE A 466 
AA2 1 2 N ASP A 541 ? N ASP A 540 O HIS A 557 ? O HIS A 556 
AA2 2 3 N ARG A 556 ? N ARG A 555 O PHE A 564 ? O PHE A 563 
AA2 3 4 N ARG A 563 ? N ARG A 562 O PHE A 627 ? O PHE A 626 
AA2 4 5 O LEU A 624 ? O LEU A 623 N LEU A 598 ? N LEU A 597 
AA2 5 6 N ALA A 594 ? N ALA A 593 O LEU A 610 ? O LEU A 609 
AA3 1 2 N GLY A 574 ? N GLY A 573 O ILE C 100 ? O ILE L 100 
AA4 1 2 N THR C 5   ? N THR L 5   O LYS C 24  ? O LYS L 24  
AA4 2 3 N MET C 21  ? N MET L 21  O LEU C 79  ? O LEU L 79  
AA4 3 4 O THR C 78  ? O THR L 78  N SER C 71  ? N SER L 71  
AA5 1 2 N MET C 13  ? N MET L 13  O GLU C 111 ? O GLU L 111 
AA5 2 3 O LEU C 110 ? O LEU L 110 N ALA C 90  ? N ALA L 90  
AA5 3 4 O TYR C 93  ? O TYR L 93  N TYR C 42  ? N TYR L 42  
AA5 4 5 N TRP C 41  ? N TRP L 41  O LEU C 53  ? O LEU L 53  
AA5 5 6 N TYR C 55  ? N TYR L 55  O THR C 59  ? O THR L 59  
AA6 1 2 N THR C 120 ? N THR L 120 O ASN C 143 ? O ASN L 143 
AA6 2 3 N LEU C 142 ? N LEU L 142 O MET C 181 ? O MET L 181 
AA6 3 4 O THR C 184 ? O THR L 184 N LEU C 166 ? N LEU L 166 
AA7 1 2 O ARG C 161 ? O ARG L 161 N TRP C 154 ? N TRP L 154 
AA7 2 3 N LYS C 153 ? N LYS L 153 O GLU C 201 ? O GLU L 201 
AA7 3 4 N TYR C 198 ? N TYR L 198 O PHE C 215 ? O PHE L 215 
AA8 1 2 N GLN D 5   ? N GLN H 5   O LYS D 23  ? O LYS H 23  
AA8 2 3 N LEU D 20  ? N LEU H 20  O LEU D 81  ? O LEU H 81  
AA8 3 4 O GLN D 82  ? O GLN H 82  N THR D 69  ? N THR H 69  
AA9 1 2 N GLU D 10  ? N GLU H 10  O THR D 117 ? O THR H 117 
AA9 2 3 O THR D 114 ? O THR H 114 N TYR D 94  ? N TYR H 94  
AA9 3 4 O TYR D 95  ? O TYR H 95  N VAL D 37  ? N VAL H 37  
AA9 4 5 N ARG D 38  ? N ARG H 38  O GLU D 46  ? O GLU H 46  
AA9 5 6 N GLU D 50  ? N GLU H 50  O TYR D 59  ? O TYR H 59  
AB1 1 2 N GLU D 10  ? N GLU H 10  O THR D 117 ? O THR H 117 
AB1 2 3 O THR D 114 ? O THR H 114 N TYR D 94  ? N TYR H 94  
AB1 3 4 N ARG D 98  ? N ARG H 98  O TYR D 109 ? O TYR H 109 
AB2 1 2 N LEU D 131 ? N LEU H 131 O GLY D 146 ? O GLY H 146 
AB2 2 3 N TYR D 152 ? N TYR H 152 O TYR D 182 ? O TYR H 182 
AB2 3 4 O LEU D 181 ? O LEU H 181 N GLN D 178 ? N GLN H 178 
AB3 1 2 N VAL D 204 ? N VAL H 204 O VAL D 213 ? O VAL H 213 
# 
_pdbx_entry_details.entry_id                   8KDG 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 NE A ARG 209 ? ? CZ  A ARG 209 ? ? NH1 A ARG 209 ? ? 116.94 120.30 -3.36  0.50 N 
2  1 NE A ARG 211 ? ? CZ  A ARG 211 ? ? NH1 A ARG 211 ? ? 116.53 120.30 -3.77  0.50 N 
3  1 NE A ARG 226 ? ? CZ  A ARG 226 ? ? NH2 A ARG 226 ? ? 117.23 120.30 -3.07  0.50 N 
4  1 CB A TYR 250 ? ? CG  A TYR 250 ? ? CD2 A TYR 250 ? ? 117.39 121.00 -3.61  0.60 N 
5  1 CB A TYR 250 ? ? CG  A TYR 250 ? ? CD1 A TYR 250 ? ? 124.72 121.00 3.72   0.60 N 
6  1 N  A LEU 261 ? ? CA  A LEU 261 ? ? CB  A LEU 261 ? ? 123.14 110.40 12.74  2.00 N 
7  1 NE A ARG 348 ? ? CZ  A ARG 348 ? ? NH1 A ARG 348 ? ? 115.46 120.30 -4.84  0.50 N 
8  1 NE A ARG 348 ? ? CZ  A ARG 348 ? ? NH2 A ARG 348 ? ? 125.51 120.30 5.21   0.50 N 
9  1 CB A TYR 468 ? ? CG  A TYR 468 ? ? CD2 A TYR 468 ? ? 116.88 121.00 -4.12  0.60 N 
10 1 CB A PHE 551 ? ? CG  A PHE 551 ? ? CD1 A PHE 551 ? ? 125.27 120.80 4.47   0.70 N 
11 1 CA A VAL 572 ? ? CB  A VAL 572 ? ? CG1 A VAL 572 ? ? 101.29 110.90 -9.61  1.50 N 
12 1 CB L TYR 93  ? ? CG  L TYR 93  ? ? CD1 L TYR 93  ? ? 125.28 121.00 4.28   0.60 N 
13 1 CB L PRO 101 ? ? CA  L PRO 101 ? ? C   L PRO 101 ? ? 96.31  112.00 -15.69 2.50 N 
14 1 N  H ARG 38  ? ? CA  H ARG 38  ? ? CB  H ARG 38  ? ? 99.73  110.60 -10.87 1.80 N 
15 1 NE H ARG 38  ? ? CZ  H ARG 38  ? ? NH1 H ARG 38  ? ? 117.11 120.30 -3.19  0.50 N 
16 1 CB H TYR 59  ? ? CG  H TYR 59  ? ? CD2 H TYR 59  ? ? 124.64 121.00 3.64   0.60 N 
17 1 CB H GLN 82  ? ? CA  H GLN 82  ? ? C   H GLN 82  ? ? 98.24  110.40 -12.16 2.00 N 
18 1 N  H TYR 103 ? ? CA  H TYR 103 ? ? CB  H TYR 103 ? ? 122.05 110.60 11.45  1.80 N 
19 1 CG H TYR 103 ? ? CD2 H TYR 103 ? ? CE2 H TYR 103 ? ? 127.06 121.30 5.76   0.80 N 
20 1 CZ H TYR 103 ? ? CE2 H TYR 103 ? ? CD2 H TYR 103 ? ? 113.95 119.80 -5.85  0.90 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 VAL A 172 ? ? -126.73 -55.57  
2  1 LYS A 257 ? ? -79.64  23.32   
3  1 ASN A 311 ? ? -95.70  50.23   
4  1 PHE A 319 ? ? 65.57   160.51  
5  1 ASP A 373 ? ? -99.39  43.23   
6  1 ALA A 438 ? ? -147.21 -50.19  
7  1 PHE A 444 ? ? -130.03 -51.22  
8  1 ALA A 486 ? ? -162.62 68.11   
9  1 HIS A 538 ? ? -160.82 22.56   
10 1 TRP A 557 ? ? -101.75 -116.10 
11 1 ASP A 558 ? ? -105.22 -66.79  
12 1 ALA A 576 ? ? -144.78 23.29   
13 1 ASN B 49  ? ? -151.41 6.78    
14 1 ILE B 139 ? ? -131.81 -49.62  
15 1 PHE B 161 ? ? -144.03 57.05   
16 1 SER B 189 ? ? -172.07 126.25  
17 1 ASN B 269 ? ? -152.21 77.92   
18 1 GLU B 356 ? ? -96.67  30.17   
19 1 LYS B 391 ? ? -82.64  -71.48  
20 1 TRP B 477 ? ? -128.81 -56.28  
21 1 LYS B 481 ? ? -145.41 59.41   
22 1 SER L 26  ? ? -68.25  0.46    
23 1 LEU L 53  ? ? -99.11  -69.05  
24 1 THR L 57  ? ? 62.40   -26.53  
25 1 SER L 83  ? ? -160.03 90.04   
26 1 ASN L 144 ? ? 62.90   68.39   
27 1 ASP H 55  ? ? -157.40 12.33   
28 1 SER H 56  ? ? 57.87   14.25   
29 1 THR H 69  ? ? -166.23 111.44  
30 1 ALA H 92  ? ? -173.11 -179.56 
31 1 TYR H 103 ? ? 92.28   -20.77  
32 1 PRO H 154 ? ? -78.91  -168.64 
# 
loop_
_pdbx_validate_peptide_omega.id 
_pdbx_validate_peptide_omega.PDB_model_num 
_pdbx_validate_peptide_omega.auth_comp_id_1 
_pdbx_validate_peptide_omega.auth_asym_id_1 
_pdbx_validate_peptide_omega.auth_seq_id_1 
_pdbx_validate_peptide_omega.PDB_ins_code_1 
_pdbx_validate_peptide_omega.label_alt_id_1 
_pdbx_validate_peptide_omega.auth_comp_id_2 
_pdbx_validate_peptide_omega.auth_asym_id_2 
_pdbx_validate_peptide_omega.auth_seq_id_2 
_pdbx_validate_peptide_omega.PDB_ins_code_2 
_pdbx_validate_peptide_omega.label_alt_id_2 
_pdbx_validate_peptide_omega.omega 
1 1 SER A 410 ? ? THR A 411 ? ? 135.33  
2 1 GLU B 356 ? ? GLY B 357 ? ? 147.81  
3 1 PRO B 360 ? ? SER B 361 ? ? -148.38 
4 1 TRP H 106 ? ? PHE H 107 ? ? -149.45 
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 209 ? ? 0.272 'SIDE CHAIN' 
2 1 ARG A 211 ? ? 0.273 'SIDE CHAIN' 
3 1 ARG A 625 ? ? 0.088 'SIDE CHAIN' 
4 1 ARG B 355 ? ? 0.096 'SIDE CHAIN' 
5 1 ARG H 100 ? ? 0.157 'SIDE CHAIN' 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8KDG 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8KDG 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.68 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               170853 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
loop_
_em_entity_assembly.id 
_em_entity_assembly.parent_id 
_em_entity_assembly.source 
_em_entity_assembly.type 
_em_entity_assembly.name 
_em_entity_assembly.details 
_em_entity_assembly.synonym 
_em_entity_assembly.oligomeric_details 
_em_entity_assembly.entity_id_list 
1 0 'MULTIPLE SOURCES' COMPLEX LAT1-CD98hc-Fab170 ? ? ? 1,2,4,3 
2 1 RECOMBINANT        COMPLEX LAT1-CD98hc        ? ? ? 1,2     
3 1 NATURAL            COMPLEX Fab170             ? ? ? 4,3     
# 
_em_imaging.entry_id                        8KDG 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8KDG 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8KDG 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A GLY 0   ? A GLY 1   
2   1 Y 1 A SER 1   ? A SER 2   
3   1 Y 1 A GLU 2   ? A GLU 3   
4   1 Y 1 A LEU 3   ? A LEU 4   
5   1 Y 1 A GLN 4   ? A GLN 5   
6   1 Y 1 A PRO 5   ? A PRO 6   
7   1 Y 1 A PRO 6   ? A PRO 7   
8   1 Y 1 A GLU 7   ? A GLU 8   
9   1 Y 1 A ALA 8   ? A ALA 9   
10  1 Y 1 A SER 9   ? A SER 10  
11  1 Y 1 A ILE 10  ? A ILE 11  
12  1 Y 1 A ALA 11  ? A ALA 12  
13  1 Y 1 A VAL 12  ? A VAL 13  
14  1 Y 1 A VAL 13  ? A VAL 14  
15  1 Y 1 A SER 14  ? A SER 15  
16  1 Y 1 A ILE 15  ? A ILE 16  
17  1 Y 1 A PRO 16  ? A PRO 17  
18  1 Y 1 A ARG 17  ? A ARG 18  
19  1 Y 1 A GLN 18  ? A GLN 19  
20  1 Y 1 A LEU 19  ? A LEU 20  
21  1 Y 1 A PRO 20  ? A PRO 21  
22  1 Y 1 A GLY 21  ? A GLY 22  
23  1 Y 1 A SER 22  ? A SER 23  
24  1 Y 1 A HIS 23  ? A HIS 24  
25  1 Y 1 A SER 24  ? A SER 25  
26  1 Y 1 A GLU 25  ? A GLU 26  
27  1 Y 1 A ALA 26  ? A ALA 27  
28  1 Y 1 A GLY 27  ? A GLY 28  
29  1 Y 1 A VAL 28  ? A VAL 29  
30  1 Y 1 A GLN 29  ? A GLN 30  
31  1 Y 1 A GLY 30  ? A GLY 31  
32  1 Y 1 A LEU 31  ? A LEU 32  
33  1 Y 1 A SER 32  ? A SER 33  
34  1 Y 1 A ALA 33  ? A ALA 34  
35  1 Y 1 A GLY 34  ? A GLY 35  
36  1 Y 1 A ASP 35  ? A ASP 36  
37  1 Y 1 A ASP 36  ? A ASP 37  
38  1 Y 1 A SER 37  ? A SER 38  
39  1 Y 1 A GLU 38  ? A GLU 39  
40  1 Y 1 A LEU 39  ? A LEU 40  
41  1 Y 1 A GLY 40  ? A GLY 41  
42  1 Y 1 A SER 41  ? A SER 42  
43  1 Y 1 A HIS 42  ? A HIS 43  
44  1 Y 1 A CYS 43  ? A CYS 44  
45  1 Y 1 A VAL 44  ? A VAL 45  
46  1 Y 1 A ALA 45  ? A ALA 46  
47  1 Y 1 A GLN 46  ? A GLN 47  
48  1 Y 1 A THR 47  ? A THR 48  
49  1 Y 1 A GLY 48  ? A GLY 49  
50  1 Y 1 A LEU 49  ? A LEU 50  
51  1 Y 1 A GLU 50  ? A GLU 51  
52  1 Y 1 A LEU 51  ? A LEU 52  
53  1 Y 1 A LEU 52  ? A LEU 53  
54  1 Y 1 A ALA 53  ? A ALA 54  
55  1 Y 1 A SER 54  ? A SER 55  
56  1 Y 1 A GLY 55  ? A GLY 56  
57  1 Y 1 A ASP 56  ? A ASP 57  
58  1 Y 1 A PRO 57  ? A PRO 58  
59  1 Y 1 A LEU 58  ? A LEU 59  
60  1 Y 1 A PRO 59  ? A PRO 60  
61  1 Y 1 A SER 60  ? A SER 61  
62  1 Y 1 A ALA 61  ? A ALA 62  
63  1 Y 1 A SER 62  ? A SER 63  
64  1 Y 1 A GLN 63  ? A GLN 64  
65  1 Y 1 A ASN 64  ? A ASN 65  
66  1 Y 1 A ALA 65  ? A ALA 66  
67  1 Y 1 A GLU 66  ? A GLU 67  
68  1 Y 1 A MET 67  ? A MET 68  
69  1 Y 1 A ILE 68  ? A ILE 69  
70  1 Y 1 A GLU 69  ? A GLU 70  
71  1 Y 1 A THR 70  ? A THR 71  
72  1 Y 1 A GLY 71  ? A GLY 72  
73  1 Y 1 A SER 72  ? A SER 73  
74  1 Y 1 A ASP 73  ? A ASP 74  
75  1 Y 1 A CYS 74  ? A CYS 75  
76  1 Y 1 A VAL 75  ? A VAL 76  
77  1 Y 1 A THR 76  ? A THR 77  
78  1 Y 1 A GLN 77  ? A GLN 78  
79  1 Y 1 A ALA 78  ? A ALA 79  
80  1 Y 1 A GLY 79  ? A GLY 80  
81  1 Y 1 A LEU 80  ? A LEU 81  
82  1 Y 1 A GLN 81  ? A GLN 82  
83  1 Y 1 A LEU 82  ? A LEU 83  
84  1 Y 1 A LEU 83  ? A LEU 84  
85  1 Y 1 A ALA 84  ? A ALA 85  
86  1 Y 1 A SER 85  ? A SER 86  
87  1 Y 1 A SER 86  ? A SER 87  
88  1 Y 1 A ASP 87  ? A ASP 88  
89  1 Y 1 A PRO 88  ? A PRO 89  
90  1 Y 1 A PRO 89  ? A PRO 90  
91  1 Y 1 A ALA 90  ? A ALA 91  
92  1 Y 1 A LEU 91  ? A LEU 92  
93  1 Y 1 A ALA 92  ? A ALA 93  
94  1 Y 1 A SER 93  ? A SER 94  
95  1 Y 1 A LYS 94  ? A LYS 95  
96  1 Y 1 A ASN 95  ? A ASN 96  
97  1 Y 1 A ALA 96  ? A ALA 97  
98  1 Y 1 A GLU 97  ? A GLU 98  
99  1 Y 1 A VAL 98  ? A VAL 99  
100 1 Y 1 A THR 99  ? A THR 100 
101 1 Y 1 A GLY 100 ? A GLY 101 
102 1 Y 1 A THR 101 ? A THR 102 
103 1 Y 1 A MET 102 ? A MET 103 
104 1 Y 1 A SER 103 ? A SER 104 
105 1 Y 1 A GLN 104 ? A GLN 105 
106 1 Y 1 A ASP 105 ? A ASP 106 
107 1 Y 1 A THR 106 ? A THR 107 
108 1 Y 1 A GLU 107 ? A GLU 108 
109 1 Y 1 A VAL 108 ? A VAL 109 
110 1 Y 1 A ASP 109 ? A ASP 110 
111 1 Y 1 A MET 110 ? A MET 111 
112 1 Y 1 A LYS 111 ? A LYS 112 
113 1 Y 1 A GLU 112 ? A GLU 113 
114 1 Y 1 A VAL 113 ? A VAL 114 
115 1 Y 1 A GLU 114 ? A GLU 115 
116 1 Y 1 A LEU 115 ? A LEU 116 
117 1 Y 1 A ASN 116 ? A ASN 117 
118 1 Y 1 A GLU 117 ? A GLU 118 
119 1 Y 1 A LEU 118 ? A LEU 119 
120 1 Y 1 A GLU 119 ? A GLU 120 
121 1 Y 1 A PRO 120 ? A PRO 121 
122 1 Y 1 A GLU 121 ? A GLU 122 
123 1 Y 1 A LYS 122 ? A LYS 123 
124 1 Y 1 A GLN 123 ? A GLN 124 
125 1 Y 1 A PRO 124 ? A PRO 125 
126 1 Y 1 A MET 125 ? A MET 126 
127 1 Y 1 A ASN 126 ? A ASN 127 
128 1 Y 1 A ALA 127 ? A ALA 128 
129 1 Y 1 A ALA 128 ? A ALA 129 
130 1 Y 1 A SER 129 ? A SER 130 
131 1 Y 1 A GLY 130 ? A GLY 131 
132 1 Y 1 A ALA 131 ? A ALA 132 
133 1 Y 1 A ALA 132 ? A ALA 133 
134 1 Y 1 A MET 133 ? A MET 134 
135 1 Y 1 A SER 134 ? A SER 135 
136 1 Y 1 A LEU 135 ? A LEU 136 
137 1 Y 1 A ALA 136 ? A ALA 137 
138 1 Y 1 A GLY 137 ? A GLY 138 
139 1 Y 1 A ALA 138 ? A ALA 139 
140 1 Y 1 A GLU 139 ? A GLU 140 
141 1 Y 1 A LYS 140 ? A LYS 141 
142 1 Y 1 A ASN 141 ? A ASN 142 
143 1 Y 1 A GLY 142 ? A GLY 143 
144 1 Y 1 A LEU 143 ? A LEU 144 
145 1 Y 1 A VAL 144 ? A VAL 145 
146 1 Y 1 A LYS 145 ? A LYS 146 
147 1 Y 1 A ILE 146 ? A ILE 147 
148 1 Y 1 A LYS 147 ? A LYS 148 
149 1 Y 1 A VAL 148 ? A VAL 149 
150 1 Y 1 A ALA 149 ? A ALA 150 
151 1 Y 1 A GLU 150 ? A GLU 151 
152 1 Y 1 A ASP 151 ? A ASP 152 
153 1 Y 1 A GLU 152 ? A GLU 153 
154 1 Y 1 A ALA 153 ? A ALA 154 
155 1 Y 1 A GLU 154 ? A GLU 155 
156 1 Y 1 A ALA 155 ? A ALA 156 
157 1 Y 1 A ALA 156 ? A ALA 157 
158 1 Y 1 A ALA 157 ? A ALA 158 
159 1 Y 1 A ALA 158 ? A ALA 159 
160 1 Y 1 A ALA 159 ? A ALA 160 
161 1 Y 1 A LYS 160 ? A LYS 161 
162 1 Y 1 A PHE 161 ? A PHE 162 
163 1 Y 1 B MET 1   ? B MET 1   
164 1 Y 1 B ALA 2   ? B ALA 2   
165 1 Y 1 B GLY 3   ? B GLY 3   
166 1 Y 1 B ALA 4   ? B ALA 4   
167 1 Y 1 B GLY 5   ? B GLY 5   
168 1 Y 1 B PRO 6   ? B PRO 6   
169 1 Y 1 B LYS 7   ? B LYS 7   
170 1 Y 1 B ARG 8   ? B ARG 8   
171 1 Y 1 B ARG 9   ? B ARG 9   
172 1 Y 1 B ALA 10  ? B ALA 10  
173 1 Y 1 B LEU 11  ? B LEU 11  
174 1 Y 1 B ALA 12  ? B ALA 12  
175 1 Y 1 B ALA 13  ? B ALA 13  
176 1 Y 1 B PRO 14  ? B PRO 14  
177 1 Y 1 B ALA 15  ? B ALA 15  
178 1 Y 1 B ALA 16  ? B ALA 16  
179 1 Y 1 B GLU 17  ? B GLU 17  
180 1 Y 1 B GLU 18  ? B GLU 18  
181 1 Y 1 B LYS 19  ? B LYS 19  
182 1 Y 1 B GLU 20  ? B GLU 20  
183 1 Y 1 B GLU 21  ? B GLU 21  
184 1 Y 1 B ALA 22  ? B ALA 22  
185 1 Y 1 B ARG 23  ? B ARG 23  
186 1 Y 1 B GLU 24  ? B GLU 24  
187 1 Y 1 B LYS 25  ? B LYS 25  
188 1 Y 1 B MET 26  ? B MET 26  
189 1 Y 1 B LEU 27  ? B LEU 27  
190 1 Y 1 B ALA 28  ? B ALA 28  
191 1 Y 1 B ALA 29  ? B ALA 29  
192 1 Y 1 B LYS 30  ? B LYS 30  
193 1 Y 1 B SER 31  ? B SER 31  
194 1 Y 1 B ALA 32  ? B ALA 32  
195 1 Y 1 B ASP 33  ? B ASP 33  
196 1 Y 1 B GLY 34  ? B GLY 34  
197 1 Y 1 B SER 35  ? B SER 35  
198 1 Y 1 B ALA 36  ? B ALA 36  
199 1 Y 1 B PRO 37  ? B PRO 37  
200 1 Y 1 B ALA 38  ? B ALA 38  
201 1 Y 1 B GLY 39  ? B GLY 39  
202 1 Y 1 B GLU 40  ? B GLU 40  
203 1 Y 1 B GLY 41  ? B GLY 41  
204 1 Y 1 B GLU 42  ? B GLU 42  
205 1 Y 1 B GLY 43  ? B GLY 43  
206 1 Y 1 B ASP 223 ? B ASP 223 
207 1 Y 1 B VAL 224 ? B VAL 224 
208 1 Y 1 B SER 225 ? B SER 225 
209 1 Y 1 B ASN 226 ? B ASN 226 
210 1 Y 1 B LEU 227 ? B LEU 227 
211 1 Y 1 B ASP 228 ? B ASP 228 
212 1 Y 1 B PRO 229 ? B PRO 229 
213 1 Y 1 B ASN 230 ? B ASN 230 
214 1 Y 1 B PHE 231 ? B PHE 231 
215 1 Y 1 B SER 232 ? B SER 232 
216 1 Y 1 B ASP 508 ? B ASP 508 
217 1 Y 1 B TYR 509 ? B TYR 509 
218 1 Y 1 B LYS 510 ? B LYS 510 
219 1 Y 1 B ASP 511 ? B ASP 511 
220 1 Y 1 B ASP 512 ? B ASP 512 
221 1 Y 1 B ASP 513 ? B ASP 513 
222 1 Y 1 B ASP 514 ? B ASP 514 
223 1 Y 1 B LYS 515 ? B LYS 515 
224 1 Y 1 L ASN 218 ? C ASN 218 
225 1 Y 1 L GLU 219 ? C GLU 219 
226 1 Y 1 L CYS 220 ? C CYS 220 
227 1 Y 1 H ASP 221 ? D ASP 221 
228 1 Y 1 H CYS 222 ? D CYS 222 
229 1 Y 1 H GLY 223 ? D GLY 223 
230 1 Y 1 H CYS 224 ? D CYS 224 
231 1 Y 1 H LYS 225 ? D LYS 225 
232 1 Y 1 H PRO 226 ? D PRO 226 
233 1 Y 1 H CYS 227 ? D CYS 227 
234 1 Y 1 H ILE 228 ? D ILE 228 
235 1 Y 1 H CYS 229 ? D CYS 229 
236 1 Y 1 H THR 230 ? D THR 230 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
NAG C1   C N R 247 
NAG C2   C N R 248 
NAG C3   C N R 249 
NAG C4   C N S 250 
NAG C5   C N R 251 
NAG C6   C N N 252 
NAG C7   C N N 253 
NAG C8   C N N 254 
NAG N2   N N N 255 
NAG O1   O N N 256 
NAG O3   O N N 257 
NAG O4   O N N 258 
NAG O5   O N N 259 
NAG O6   O N N 260 
NAG O7   O N N 261 
NAG H1   H N N 262 
NAG H2   H N N 263 
NAG H3   H N N 264 
NAG H4   H N N 265 
NAG H5   H N N 266 
NAG H61  H N N 267 
NAG H62  H N N 268 
NAG H81  H N N 269 
NAG H82  H N N 270 
NAG H83  H N N 271 
NAG HN2  H N N 272 
NAG HO1  H N N 273 
NAG HO3  H N N 274 
NAG HO4  H N N 275 
NAG HO6  H N N 276 
PHE N    N N N 277 
PHE CA   C N S 278 
PHE C    C N N 279 
PHE O    O N N 280 
PHE CB   C N N 281 
PHE CG   C Y N 282 
PHE CD1  C Y N 283 
PHE CD2  C Y N 284 
PHE CE1  C Y N 285 
PHE CE2  C Y N 286 
PHE CZ   C Y N 287 
PHE OXT  O N N 288 
PHE H    H N N 289 
PHE H2   H N N 290 
PHE HA   H N N 291 
PHE HB2  H N N 292 
PHE HB3  H N N 293 
PHE HD1  H N N 294 
PHE HD2  H N N 295 
PHE HE1  H N N 296 
PHE HE2  H N N 297 
PHE HZ   H N N 298 
PHE HXT  H N N 299 
PRO N    N N N 300 
PRO CA   C N S 301 
PRO C    C N N 302 
PRO O    O N N 303 
PRO CB   C N N 304 
PRO CG   C N N 305 
PRO CD   C N N 306 
PRO OXT  O N N 307 
PRO H    H N N 308 
PRO HA   H N N 309 
PRO HB2  H N N 310 
PRO HB3  H N N 311 
PRO HG2  H N N 312 
PRO HG3  H N N 313 
PRO HD2  H N N 314 
PRO HD3  H N N 315 
PRO HXT  H N N 316 
SER N    N N N 317 
SER CA   C N S 318 
SER C    C N N 319 
SER O    O N N 320 
SER CB   C N N 321 
SER OG   O N N 322 
SER OXT  O N N 323 
SER H    H N N 324 
SER H2   H N N 325 
SER HA   H N N 326 
SER HB2  H N N 327 
SER HB3  H N N 328 
SER HG   H N N 329 
SER HXT  H N N 330 
THR N    N N N 331 
THR CA   C N S 332 
THR C    C N N 333 
THR O    O N N 334 
THR CB   C N R 335 
THR OG1  O N N 336 
THR CG2  C N N 337 
THR OXT  O N N 338 
THR H    H N N 339 
THR H2   H N N 340 
THR HA   H N N 341 
THR HB   H N N 342 
THR HG1  H N N 343 
THR HG21 H N N 344 
THR HG22 H N N 345 
THR HG23 H N N 346 
THR HXT  H N N 347 
TRP N    N N N 348 
TRP CA   C N S 349 
TRP C    C N N 350 
TRP O    O N N 351 
TRP CB   C N N 352 
TRP CG   C Y N 353 
TRP CD1  C Y N 354 
TRP CD2  C Y N 355 
TRP NE1  N Y N 356 
TRP CE2  C Y N 357 
TRP CE3  C Y N 358 
TRP CZ2  C Y N 359 
TRP CZ3  C Y N 360 
TRP CH2  C Y N 361 
TRP OXT  O N N 362 
TRP H    H N N 363 
TRP H2   H N N 364 
TRP HA   H N N 365 
TRP HB2  H N N 366 
TRP HB3  H N N 367 
TRP HD1  H N N 368 
TRP HE1  H N N 369 
TRP HE3  H N N 370 
TRP HZ2  H N N 371 
TRP HZ3  H N N 372 
TRP HH2  H N N 373 
TRP HXT  H N N 374 
TYR N    N N N 375 
TYR CA   C N S 376 
TYR C    C N N 377 
TYR O    O N N 378 
TYR CB   C N N 379 
TYR CG   C Y N 380 
TYR CD1  C Y N 381 
TYR CD2  C Y N 382 
TYR CE1  C Y N 383 
TYR CE2  C Y N 384 
TYR CZ   C Y N 385 
TYR OH   O N N 386 
TYR OXT  O N N 387 
TYR H    H N N 388 
TYR H2   H N N 389 
TYR HA   H N N 390 
TYR HB2  H N N 391 
TYR HB3  H N N 392 
TYR HD1  H N N 393 
TYR HD2  H N N 394 
TYR HE1  H N N 395 
TYR HE2  H N N 396 
TYR HH   H N N 397 
TYR HXT  H N N 398 
VAL N    N N N 399 
VAL CA   C N S 400 
VAL C    C N N 401 
VAL O    O N N 402 
VAL CB   C N N 403 
VAL CG1  C N N 404 
VAL CG2  C N N 405 
VAL OXT  O N N 406 
VAL H    H N N 407 
VAL H2   H N N 408 
VAL HA   H N N 409 
VAL HB   H N N 410 
VAL HG11 H N N 411 
VAL HG12 H N N 412 
VAL HG13 H N N 413 
VAL HG21 H N N 414 
VAL HG22 H N N 415 
VAL HG23 H N N 416 
VAL HXT  H N N 417 
VU0 N1   N N N 418 
VU0 C1   C N R 419 
VU0 C2   C N N 420 
VU0 C3   C N R 421 
VU0 C4   C N N 422 
VU0 C5   C N N 423 
VU0 C6   C N S 424 
VU0 C7   C N N 425 
VU0 C8   C N N 426 
VU0 O1   O N N 427 
VU0 O2   O N N 428 
VU0 H1   H N N 429 
VU0 H2   H N N 430 
VU0 H4   H N N 431 
VU0 H5   H N N 432 
VU0 H6   H N N 433 
VU0 H7   H N N 434 
VU0 H8   H N N 435 
VU0 H9   H N N 436 
VU0 H10  H N N 437 
VU0 H11  H N N 438 
VU0 H12  H N N 439 
VU0 H13  H N N 440 
VU0 H14  H N N 441 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
NAG C1  C2   sing N N 235 
NAG C1  O1   sing N N 236 
NAG C1  O5   sing N N 237 
NAG C1  H1   sing N N 238 
NAG C2  C3   sing N N 239 
NAG C2  N2   sing N N 240 
NAG C2  H2   sing N N 241 
NAG C3  C4   sing N N 242 
NAG C3  O3   sing N N 243 
NAG C3  H3   sing N N 244 
NAG C4  C5   sing N N 245 
NAG C4  O4   sing N N 246 
NAG C4  H4   sing N N 247 
NAG C5  C6   sing N N 248 
NAG C5  O5   sing N N 249 
NAG C5  H5   sing N N 250 
NAG C6  O6   sing N N 251 
NAG C6  H61  sing N N 252 
NAG C6  H62  sing N N 253 
NAG C7  C8   sing N N 254 
NAG C7  N2   sing N N 255 
NAG C7  O7   doub N N 256 
NAG C8  H81  sing N N 257 
NAG C8  H82  sing N N 258 
NAG C8  H83  sing N N 259 
NAG N2  HN2  sing N N 260 
NAG O1  HO1  sing N N 261 
NAG O3  HO3  sing N N 262 
NAG O4  HO4  sing N N 263 
NAG O6  HO6  sing N N 264 
PHE N   CA   sing N N 265 
PHE N   H    sing N N 266 
PHE N   H2   sing N N 267 
PHE CA  C    sing N N 268 
PHE CA  CB   sing N N 269 
PHE CA  HA   sing N N 270 
PHE C   O    doub N N 271 
PHE C   OXT  sing N N 272 
PHE CB  CG   sing N N 273 
PHE CB  HB2  sing N N 274 
PHE CB  HB3  sing N N 275 
PHE CG  CD1  doub Y N 276 
PHE CG  CD2  sing Y N 277 
PHE CD1 CE1  sing Y N 278 
PHE CD1 HD1  sing N N 279 
PHE CD2 CE2  doub Y N 280 
PHE CD2 HD2  sing N N 281 
PHE CE1 CZ   doub Y N 282 
PHE CE1 HE1  sing N N 283 
PHE CE2 CZ   sing Y N 284 
PHE CE2 HE2  sing N N 285 
PHE CZ  HZ   sing N N 286 
PHE OXT HXT  sing N N 287 
PRO N   CA   sing N N 288 
PRO N   CD   sing N N 289 
PRO N   H    sing N N 290 
PRO CA  C    sing N N 291 
PRO CA  CB   sing N N 292 
PRO CA  HA   sing N N 293 
PRO C   O    doub N N 294 
PRO C   OXT  sing N N 295 
PRO CB  CG   sing N N 296 
PRO CB  HB2  sing N N 297 
PRO CB  HB3  sing N N 298 
PRO CG  CD   sing N N 299 
PRO CG  HG2  sing N N 300 
PRO CG  HG3  sing N N 301 
PRO CD  HD2  sing N N 302 
PRO CD  HD3  sing N N 303 
PRO OXT HXT  sing N N 304 
SER N   CA   sing N N 305 
SER N   H    sing N N 306 
SER N   H2   sing N N 307 
SER CA  C    sing N N 308 
SER CA  CB   sing N N 309 
SER CA  HA   sing N N 310 
SER C   O    doub N N 311 
SER C   OXT  sing N N 312 
SER CB  OG   sing N N 313 
SER CB  HB2  sing N N 314 
SER CB  HB3  sing N N 315 
SER OG  HG   sing N N 316 
SER OXT HXT  sing N N 317 
THR N   CA   sing N N 318 
THR N   H    sing N N 319 
THR N   H2   sing N N 320 
THR CA  C    sing N N 321 
THR CA  CB   sing N N 322 
THR CA  HA   sing N N 323 
THR C   O    doub N N 324 
THR C   OXT  sing N N 325 
THR CB  OG1  sing N N 326 
THR CB  CG2  sing N N 327 
THR CB  HB   sing N N 328 
THR OG1 HG1  sing N N 329 
THR CG2 HG21 sing N N 330 
THR CG2 HG22 sing N N 331 
THR CG2 HG23 sing N N 332 
THR OXT HXT  sing N N 333 
TRP N   CA   sing N N 334 
TRP N   H    sing N N 335 
TRP N   H2   sing N N 336 
TRP CA  C    sing N N 337 
TRP CA  CB   sing N N 338 
TRP CA  HA   sing N N 339 
TRP C   O    doub N N 340 
TRP C   OXT  sing N N 341 
TRP CB  CG   sing N N 342 
TRP CB  HB2  sing N N 343 
TRP CB  HB3  sing N N 344 
TRP CG  CD1  doub Y N 345 
TRP CG  CD2  sing Y N 346 
TRP CD1 NE1  sing Y N 347 
TRP CD1 HD1  sing N N 348 
TRP CD2 CE2  doub Y N 349 
TRP CD2 CE3  sing Y N 350 
TRP NE1 CE2  sing Y N 351 
TRP NE1 HE1  sing N N 352 
TRP CE2 CZ2  sing Y N 353 
TRP CE3 CZ3  doub Y N 354 
TRP CE3 HE3  sing N N 355 
TRP CZ2 CH2  doub Y N 356 
TRP CZ2 HZ2  sing N N 357 
TRP CZ3 CH2  sing Y N 358 
TRP CZ3 HZ3  sing N N 359 
TRP CH2 HH2  sing N N 360 
TRP OXT HXT  sing N N 361 
TYR N   CA   sing N N 362 
TYR N   H    sing N N 363 
TYR N   H2   sing N N 364 
TYR CA  C    sing N N 365 
TYR CA  CB   sing N N 366 
TYR CA  HA   sing N N 367 
TYR C   O    doub N N 368 
TYR C   OXT  sing N N 369 
TYR CB  CG   sing N N 370 
TYR CB  HB2  sing N N 371 
TYR CB  HB3  sing N N 372 
TYR CG  CD1  doub Y N 373 
TYR CG  CD2  sing Y N 374 
TYR CD1 CE1  sing Y N 375 
TYR CD1 HD1  sing N N 376 
TYR CD2 CE2  doub Y N 377 
TYR CD2 HD2  sing N N 378 
TYR CE1 CZ   doub Y N 379 
TYR CE1 HE1  sing N N 380 
TYR CE2 CZ   sing Y N 381 
TYR CE2 HE2  sing N N 382 
TYR CZ  OH   sing N N 383 
TYR OH  HH   sing N N 384 
TYR OXT HXT  sing N N 385 
VAL N   CA   sing N N 386 
VAL N   H    sing N N 387 
VAL N   H2   sing N N 388 
VAL CA  C    sing N N 389 
VAL CA  CB   sing N N 390 
VAL CA  HA   sing N N 391 
VAL C   O    doub N N 392 
VAL C   OXT  sing N N 393 
VAL CB  CG1  sing N N 394 
VAL CB  CG2  sing N N 395 
VAL CB  HB   sing N N 396 
VAL CG1 HG11 sing N N 397 
VAL CG1 HG12 sing N N 398 
VAL CG1 HG13 sing N N 399 
VAL CG2 HG21 sing N N 400 
VAL CG2 HG22 sing N N 401 
VAL CG2 HG23 sing N N 402 
VAL OXT HXT  sing N N 403 
VU0 C5  C4   sing N N 404 
VU0 C5  C6   sing N N 405 
VU0 C4  C3   sing N N 406 
VU0 N1  C1   sing N N 407 
VU0 C6  C1   sing N N 408 
VU0 C6  C7   sing N N 409 
VU0 C3  C7   sing N N 410 
VU0 C3  C2   sing N N 411 
VU0 C1  C2   sing N N 412 
VU0 C1  C8   sing N N 413 
VU0 C8  O2   doub N N 414 
VU0 C8  O1   sing N N 415 
VU0 N1  H1   sing N N 416 
VU0 N1  H2   sing N N 417 
VU0 C2  H4   sing N N 418 
VU0 C2  H5   sing N N 419 
VU0 C3  H6   sing N N 420 
VU0 C4  H7   sing N N 421 
VU0 C4  H8   sing N N 422 
VU0 C5  H9   sing N N 423 
VU0 C5  H10  sing N N 424 
VU0 C6  H11  sing N N 425 
VU0 C7  H12  sing N N 426 
VU0 C7  H13  sing N N 427 
VU0 O1  H14  sing N N 428 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-08-09 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8KDG 
_em_admin.last_update        2025-02-26 
_em_admin.map_release_date   2025-02-12 
_em_admin.title              'Structure of LAT1-CD98hc-Fab170 in complex with BCH, consensus map' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.173 
# 
loop_
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
_em_entity_assembly_naturalsource.details 
? ? 2 2 9606  'Homo sapiens' ? ? ? ? ? 
? ? 3 3 10090 'Mus musculus' ? ? ? ? ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         51 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Max Planck Society' 
_pdbx_audit_support.country                Germany 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8KDG 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . THR A 1 163 ? 103.570 115.840 58.748  1.00 328.66 ? 162 THR A N   1 
ATOM   2     C CA  . THR A 1 163 ? 103.920 117.277 58.952  1.00 375.98 ? 162 THR A CA  1 
ATOM   3     C C   . THR A 1 163 ? 105.405 117.421 59.310  1.00 375.75 ? 162 THR A C   1 
ATOM   4     O O   . THR A 1 163 ? 105.755 117.795 60.432  1.00 316.88 ? 162 THR A O   1 
ATOM   5     C CB  . THR A 1 163 ? 103.014 117.934 60.010  1.00 397.90 ? 162 THR A CB  1 
ATOM   6     O OG1 . THR A 1 163 ? 103.218 117.324 61.286  1.00 438.54 ? 162 THR A OG1 1 
ATOM   7     C CG2 . THR A 1 163 ? 101.543 117.852 59.665  1.00 352.66 ? 162 THR A CG2 1 
ATOM   8     N N   . GLY A 1 164 ? 106.273 117.128 58.332  1.00 367.27 ? 163 GLY A N   1 
ATOM   9     C CA  . GLY A 1 164 ? 107.716 117.159 58.515  1.00 359.32 ? 163 GLY A CA  1 
ATOM   10    C C   . GLY A 1 164 ? 108.459 116.728 57.252  1.00 317.37 ? 163 GLY A C   1 
ATOM   11    O O   . GLY A 1 164 ? 107.865 116.669 56.172  1.00 261.39 ? 163 GLY A O   1 
ATOM   12    N N   . LEU A 1 165 ? 109.752 116.413 57.420  1.00 287.86 ? 164 LEU A N   1 
ATOM   13    C CA  . LEU A 1 165 ? 110.616 115.967 56.332  1.00 254.22 ? 164 LEU A CA  1 
ATOM   14    C C   . LEU A 1 165 ? 110.197 114.558 55.890  1.00 276.34 ? 164 LEU A C   1 
ATOM   15    O O   . LEU A 1 165 ? 109.895 113.705 56.726  1.00 351.21 ? 164 LEU A O   1 
ATOM   16    C CB  . LEU A 1 165 ? 112.093 115.946 56.768  1.00 225.66 ? 164 LEU A CB  1 
ATOM   17    C CG  . LEU A 1 165 ? 112.660 117.163 57.503  1.00 255.92 ? 164 LEU A CG  1 
ATOM   18    C CD1 . LEU A 1 165 ? 114.170 117.004 57.649  1.00 257.18 ? 164 LEU A CD1 1 
ATOM   19    C CD2 . LEU A 1 165 ? 112.316 118.486 56.818  1.00 269.28 ? 164 LEU A CD2 1 
ATOM   20    N N   . SER A 1 166 ? 110.191 114.309 54.571  1.00 287.79 ? 165 SER A N   1 
ATOM   21    C CA  . SER A 1 166 ? 110.095 112.966 54.006  1.00 276.86 ? 165 SER A CA  1 
ATOM   22    C C   . SER A 1 166 ? 111.393 112.185 54.228  1.00 229.60 ? 165 SER A C   1 
ATOM   23    O O   . SER A 1 166 ? 112.374 112.729 54.762  1.00 193.81 ? 165 SER A O   1 
ATOM   24    C CB  . SER A 1 166 ? 109.779 113.041 52.532  1.00 342.40 ? 165 SER A CB  1 
ATOM   25    O OG  . SER A 1 166 ? 110.907 113.503 51.791  1.00 342.51 ? 165 SER A OG  1 
ATOM   26    N N   . LYS A 1 167 ? 111.396 110.904 53.796  1.00 230.22 ? 166 LYS A N   1 
ATOM   27    C CA  . LYS A 1 167 ? 112.605 110.076 53.793  1.00 287.98 ? 166 LYS A CA  1 
ATOM   28    C C   . LYS A 1 167 ? 113.753 110.750 53.022  1.00 301.80 ? 166 LYS A C   1 
ATOM   29    O O   . LYS A 1 167 ? 114.903 110.767 53.493  1.00 221.40 ? 166 LYS A O   1 
ATOM   30    C CB  . LYS A 1 167 ? 112.344 108.681 53.199  1.00 257.63 ? 166 LYS A CB  1 
ATOM   31    C CG  . LYS A 1 167 ? 113.581 107.785 53.218  1.00 270.21 ? 166 LYS A CG  1 
ATOM   32    C CD  . LYS A 1 167 ? 113.415 106.405 52.615  1.00 259.83 ? 166 LYS A CD  1 
ATOM   33    C CE  . LYS A 1 167 ? 114.575 105.485 52.962  1.00 292.98 ? 166 LYS A CE  1 
ATOM   34    N NZ  . LYS A 1 167 ? 115.893 105.978 52.480  1.00 292.48 ? 166 LYS A NZ  1 
ATOM   35    N N   . GLU A 1 168 ? 113.398 111.275 51.835  1.00 355.41 ? 167 GLU A N   1 
ATOM   36    C CA  . GLU A 1 168 ? 114.295 111.931 50.899  1.00 396.22 ? 167 GLU A CA  1 
ATOM   37    C C   . GLU A 1 168 ? 114.886 113.179 51.546  1.00 364.94 ? 167 GLU A C   1 
ATOM   38    O O   . GLU A 1 168 ? 116.098 113.354 51.509  1.00 391.83 ? 167 GLU A O   1 
ATOM   39    C CB  . GLU A 1 168 ? 113.518 112.253 49.616  1.00 469.25 ? 167 GLU A CB  1 
ATOM   40    C CG  . GLU A 1 168 ? 114.321 112.961 48.531  1.00 519.94 ? 167 GLU A CG  1 
ATOM   41    C CD  . GLU A 1 168 ? 113.501 113.409 47.330  1.00 548.44 ? 167 GLU A CD  1 
ATOM   42    O OE1 . GLU A 1 168 ? 112.762 112.569 46.777  1.00 564.03 ? 167 GLU A OE1 1 
ATOM   43    O OE2 . GLU A 1 168 ? 113.604 114.598 46.944  1.00 541.34 ? 167 GLU A OE2 1 
ATOM   44    N N   . GLU A 1 169 ? 114.022 114.028 52.122  1.00 339.41 ? 168 GLU A N   1 
ATOM   45    C CA  . GLU A 1 169 ? 114.443 115.266 52.766  1.00 357.79 ? 168 GLU A CA  1 
ATOM   46    C C   . GLU A 1 169 ? 115.297 114.999 54.011  1.00 326.92 ? 168 GLU A C   1 
ATOM   47    O O   . GLU A 1 169 ? 116.249 115.751 54.246  1.00 319.82 ? 168 GLU A O   1 
ATOM   48    C CB  . GLU A 1 169 ? 113.231 116.124 53.131  1.00 360.42 ? 168 GLU A CB  1 
ATOM   49    C CG  . GLU A 1 169 ? 112.495 116.709 51.938  1.00 357.51 ? 168 GLU A CG  1 
ATOM   50    C CD  . GLU A 1 169 ? 111.196 117.416 52.296  1.00 359.15 ? 168 GLU A CD  1 
ATOM   51    O OE1 . GLU A 1 169 ? 110.304 116.746 52.862  1.00 394.97 ? 168 GLU A OE1 1 
ATOM   52    O OE2 . GLU A 1 169 ? 111.073 118.631 52.013  1.00 333.89 ? 168 GLU A OE2 1 
ATOM   53    N N   . LEU A 1 170 ? 114.973 113.952 54.793  1.00 271.63 ? 169 LEU A N   1 
ATOM   54    C CA  . LEU A 1 170 ? 115.769 113.631 55.973  1.00 281.35 ? 169 LEU A CA  1 
ATOM   55    C C   . LEU A 1 170 ? 117.181 113.170 55.588  1.00 347.16 ? 169 LEU A C   1 
ATOM   56    O O   . LEU A 1 170 ? 118.152 113.730 56.100  1.00 404.57 ? 169 LEU A O   1 
ATOM   57    C CB  . LEU A 1 170 ? 115.079 112.574 56.837  1.00 331.37 ? 169 LEU A CB  1 
ATOM   58    C CG  . LEU A 1 170 ? 115.863 112.173 58.097  1.00 405.91 ? 169 LEU A CG  1 
ATOM   59    C CD1 . LEU A 1 170 ? 115.853 113.277 59.150  1.00 427.70 ? 169 LEU A CD1 1 
ATOM   60    C CD2 . LEU A 1 170 ? 115.326 110.883 58.691  1.00 461.37 ? 169 LEU A CD2 1 
ATOM   61    N N   . LEU A 1 171 ? 117.308 112.164 54.708  1.00 347.09 ? 170 LEU A N   1 
ATOM   62    C CA  . LEU A 1 171 ? 118.622 111.615 54.372  1.00 386.00 ? 170 LEU A CA  1 
ATOM   63    C C   . LEU A 1 171 ? 119.518 112.661 53.678  1.00 408.36 ? 170 LEU A C   1 
ATOM   64    O O   . LEU A 1 171 ? 120.743 112.570 53.762  1.00 401.44 ? 170 LEU A O   1 
ATOM   65    C CB  . LEU A 1 171 ? 118.419 110.352 53.520  1.00 399.95 ? 170 LEU A CB  1 
ATOM   66    C CG  . LEU A 1 171 ? 119.666 109.515 53.225  1.00 446.18 ? 170 LEU A CG  1 
ATOM   67    C CD1 . LEU A 1 171 ? 120.292 108.957 54.496  1.00 435.33 ? 170 LEU A CD1 1 
ATOM   68    C CD2 . LEU A 1 171 ? 119.329 108.381 52.271  1.00 466.05 ? 170 LEU A CD2 1 
ATOM   69    N N   . LYS A 1 172 ? 118.915 113.663 53.012  1.00 416.69 ? 171 LYS A N   1 
ATOM   70    C CA  . LYS A 1 172 ? 119.623 114.787 52.404  1.00 425.36 ? 171 LYS A CA  1 
ATOM   71    C C   . LYS A 1 172 ? 120.151 115.809 53.427  1.00 377.09 ? 171 LYS A C   1 
ATOM   72    O O   . LYS A 1 172 ? 120.861 116.729 53.021  1.00 411.78 ? 171 LYS A O   1 
ATOM   73    C CB  . LYS A 1 172 ? 118.676 115.459 51.397  1.00 471.47 ? 171 LYS A CB  1 
ATOM   74    C CG  . LYS A 1 172 ? 119.307 116.420 50.395  1.00 499.50 ? 171 LYS A CG  1 
ATOM   75    C CD  . LYS A 1 172 ? 118.464 116.662 49.149  1.00 524.92 ? 171 LYS A CD  1 
ATOM   76    C CE  . LYS A 1 172 ? 117.113 117.306 49.402  1.00 558.95 ? 171 LYS A CE  1 
ATOM   77    N NZ  . LYS A 1 172 ? 117.226 118.721 49.836  1.00 560.01 ? 171 LYS A NZ  1 
ATOM   78    N N   . VAL A 1 173 ? 119.828 115.681 54.733  1.00 337.77 ? 172 VAL A N   1 
ATOM   79    C CA  . VAL A 1 173 ? 120.276 116.612 55.774  1.00 356.50 ? 172 VAL A CA  1 
ATOM   80    C C   . VAL A 1 173 ? 120.963 115.864 56.925  1.00 365.48 ? 172 VAL A C   1 
ATOM   81    O O   . VAL A 1 173 ? 122.111 116.185 57.257  1.00 363.87 ? 172 VAL A O   1 
ATOM   82    C CB  . VAL A 1 173 ? 119.097 117.478 56.279  1.00 345.70 ? 172 VAL A CB  1 
ATOM   83    C CG1 . VAL A 1 173 ? 119.469 118.350 57.484  1.00 294.06 ? 172 VAL A CG1 1 
ATOM   84    C CG2 . VAL A 1 173 ? 118.516 118.321 55.149  1.00 358.65 ? 172 VAL A CG2 1 
ATOM   85    N N   . ALA A 1 174 ? 120.248 114.886 57.513  1.00 413.13 ? 173 ALA A N   1 
ATOM   86    C CA  . ALA A 1 174 ? 120.637 114.223 58.752  1.00 438.51 ? 173 ALA A CA  1 
ATOM   87    C C   . ALA A 1 174 ? 121.796 113.230 58.576  1.00 393.42 ? 173 ALA A C   1 
ATOM   88    O O   . ALA A 1 174 ? 122.309 112.749 59.594  1.00 384.54 ? 173 ALA A O   1 
ATOM   89    C CB  . ALA A 1 174 ? 119.409 113.548 59.342  1.00 477.85 ? 173 ALA A CB  1 
ATOM   90    N N   . GLY A 1 175 ? 122.200 112.931 57.321  1.00 327.00 ? 174 GLY A N   1 
ATOM   91    C CA  . GLY A 1 175 ? 123.396 112.158 57.007  1.00 313.21 ? 174 GLY A CA  1 
ATOM   92    C C   . GLY A 1 175 ? 124.718 112.942 57.018  1.00 367.49 ? 174 GLY A C   1 
ATOM   93    O O   . GLY A 1 175 ? 125.757 112.330 56.776  1.00 366.83 ? 174 GLY A O   1 
ATOM   94    N N   . SER A 1 176 ? 124.688 114.267 57.290  1.00 423.10 ? 175 SER A N   1 
ATOM   95    C CA  . SER A 1 176 ? 125.878 115.113 57.383  1.00 426.60 ? 175 SER A CA  1 
ATOM   96    C C   . SER A 1 176 ? 126.823 114.646 58.498  1.00 434.05 ? 175 SER A C   1 
ATOM   97    O O   . SER A 1 176 ? 126.340 114.335 59.587  1.00 529.04 ? 175 SER A O   1 
ATOM   98    C CB  . SER A 1 176 ? 125.512 116.561 57.623  1.00 398.78 ? 175 SER A CB  1 
ATOM   99    O OG  . SER A 1 176 ? 124.610 117.050 56.641  1.00 438.53 ? 175 SER A OG  1 
ATOM   100   N N   . PRO A 1 177 ? 128.170 114.582 58.291  1.00 378.90 ? 176 PRO A N   1 
ATOM   101   C CA  . PRO A 1 177 ? 129.115 114.145 59.333  1.00 388.69 ? 176 PRO A CA  1 
ATOM   102   C C   . PRO A 1 177 ? 128.999 114.800 60.717  1.00 426.53 ? 176 PRO A C   1 
ATOM   103   O O   . PRO A 1 177 ? 129.283 114.133 61.714  1.00 454.78 ? 176 PRO A O   1 
ATOM   104   C CB  . PRO A 1 177 ? 130.491 114.450 58.713  1.00 401.42 ? 176 PRO A CB  1 
ATOM   105   C CG  . PRO A 1 177 ? 130.246 114.286 57.237  1.00 401.03 ? 176 PRO A CG  1 
ATOM   106   C CD  . PRO A 1 177 ? 128.876 114.900 57.036  1.00 383.98 ? 176 PRO A CD  1 
ATOM   107   N N   . GLY A 1 178 ? 128.572 116.077 60.780  1.00 402.31 ? 177 GLY A N   1 
ATOM   108   C CA  . GLY A 1 178 ? 128.277 116.761 62.038  1.00 386.78 ? 177 GLY A CA  1 
ATOM   109   C C   . GLY A 1 178 ? 127.131 116.119 62.829  1.00 351.31 ? 177 GLY A C   1 
ATOM   110   O O   . GLY A 1 178 ? 127.231 115.910 64.045  1.00 300.49 ? 177 GLY A O   1 
ATOM   111   N N   . TRP A 1 179 ? 126.035 115.795 62.129  1.00 311.94 ? 178 TRP A N   1 
ATOM   112   C CA  . TRP A 1 179 ? 124.920 115.089 62.750  1.00 223.65 ? 178 TRP A CA  1 
ATOM   113   C C   . TRP A 1 179 ? 125.289 113.633 63.051  1.00 195.61 ? 178 TRP A C   1 
ATOM   114   O O   . TRP A 1 179 ? 124.865 113.145 64.088  1.00 302.55 ? 178 TRP A O   1 
ATOM   115   C CB  . TRP A 1 179 ? 123.637 115.193 61.917  1.00 256.03 ? 178 TRP A CB  1 
ATOM   116   C CG  . TRP A 1 179 ? 123.053 116.586 61.857  1.00 321.14 ? 178 TRP A CG  1 
ATOM   117   C CD1 . TRP A 1 179 ? 122.755 117.236 60.698  1.00 364.25 ? 178 TRP A CD1 1 
ATOM   118   C CD2 . TRP A 1 179 ? 122.689 117.499 62.928  1.00 282.64 ? 178 TRP A CD2 1 
ATOM   119   N NE1 . TRP A 1 179 ? 122.236 118.477 60.958  1.00 354.98 ? 178 TRP A NE1 1 
ATOM   120   C CE2 . TRP A 1 179 ? 122.185 118.670 62.316  1.00 339.13 ? 178 TRP A CE2 1 
ATOM   121   C CE3 . TRP A 1 179 ? 122.747 117.449 64.326  1.00 255.39 ? 178 TRP A CE3 1 
ATOM   122   C CZ2 . TRP A 1 179 ? 121.740 119.766 63.062  1.00 327.11 ? 178 TRP A CZ2 1 
ATOM   123   C CZ3 . TRP A 1 179 ? 122.307 118.533 65.060  1.00 291.63 ? 178 TRP A CZ3 1 
ATOM   124   C CH2 . TRP A 1 179 ? 121.809 119.677 64.436  1.00 281.50 ? 178 TRP A CH2 1 
ATOM   125   N N   . VAL A 1 180 ? 126.082 112.949 62.200  1.00 219.88 ? 179 VAL A N   1 
ATOM   126   C CA  . VAL A 1 180 ? 126.563 111.587 62.467  1.00 248.05 ? 179 VAL A CA  1 
ATOM   127   C C   . VAL A 1 180 ? 127.391 111.547 63.759  1.00 260.29 ? 179 VAL A C   1 
ATOM   128   O O   . VAL A 1 180 ? 127.146 110.674 64.599  1.00 350.79 ? 179 VAL A O   1 
ATOM   129   C CB  . VAL A 1 180 ? 127.345 110.978 61.279  1.00 271.03 ? 179 VAL A CB  1 
ATOM   130   C CG1 . VAL A 1 180 ? 128.052 109.656 61.616  1.00 234.82 ? 179 VAL A CG1 1 
ATOM   131   C CG2 . VAL A 1 180 ? 126.439 110.814 60.056  1.00 342.93 ? 179 VAL A CG2 1 
ATOM   132   N N   . ARG A 1 181 ? 128.339 112.481 63.922  1.00 226.65 ? 180 ARG A N   1 
ATOM   133   C CA  . ARG A 1 181 ? 129.145 112.562 65.134  1.00 284.90 ? 180 ARG A CA  1 
ATOM   134   C C   . ARG A 1 181 ? 128.283 112.951 66.347  1.00 293.71 ? 180 ARG A C   1 
ATOM   135   O O   . ARG A 1 181 ? 128.494 112.388 67.425  1.00 304.25 ? 180 ARG A O   1 
ATOM   136   C CB  . ARG A 1 181 ? 130.330 113.515 64.925  1.00 372.69 ? 180 ARG A CB  1 
ATOM   137   C CG  . ARG A 1 181 ? 131.397 112.987 63.975  1.00 399.56 ? 180 ARG A CG  1 
ATOM   138   C CD  . ARG A 1 181 ? 132.503 114.006 63.763  1.00 419.60 ? 180 ARG A CD  1 
ATOM   139   N NE  . ARG A 1 181 ? 133.423 114.077 64.919  1.00 396.27 ? 180 ARG A NE  1 
ATOM   140   C CZ  . ARG A 1 181 ? 134.612 114.708 64.955  1.00 306.66 ? 180 ARG A CZ  1 
ATOM   141   N NH1 . ARG A 1 181 ? 135.372 114.695 66.048  1.00 186.36 ? 180 ARG A NH1 1 
ATOM   142   N NH2 . ARG A 1 181 ? 135.050 115.359 63.889  1.00 317.49 ? 180 ARG A NH2 1 
ATOM   143   N N   . THR A 1 182 ? 127.327 113.892 66.187  1.00 308.36 ? 181 THR A N   1 
ATOM   144   C CA  . THR A 1 182 ? 126.390 114.253 67.255  1.00 301.72 ? 181 THR A CA  1 
ATOM   145   C C   . THR A 1 182 ? 125.582 113.029 67.715  1.00 213.20 ? 181 THR A C   1 
ATOM   146   O O   . THR A 1 182 ? 125.481 112.791 68.912  1.00 176.90 ? 181 THR A O   1 
ATOM   147   C CB  . THR A 1 182 ? 125.450 115.407 66.855  1.00 302.86 ? 181 THR A CB  1 
ATOM   148   O OG1 . THR A 1 182 ? 126.249 116.534 66.482  1.00 295.42 ? 181 THR A OG1 1 
ATOM   149   C CG2 . THR A 1 182 ? 124.474 115.812 67.950  1.00 220.79 ? 181 THR A CG2 1 
ATOM   150   N N   . ARG A 1 183 ? 125.025 112.269 66.762  1.00 223.88 ? 182 ARG A N   1 
ATOM   151   C CA  . ARG A 1 183 ? 124.218 111.084 67.034  1.00 248.69 ? 182 ARG A CA  1 
ATOM   152   C C   . ARG A 1 183 ? 125.049 109.992 67.724  1.00 256.50 ? 182 ARG A C   1 
ATOM   153   O O   . ARG A 1 183 ? 124.547 109.394 68.687  1.00 392.36 ? 182 ARG A O   1 
ATOM   154   C CB  . ARG A 1 183 ? 123.579 110.596 65.730  1.00 297.34 ? 182 ARG A CB  1 
ATOM   155   C CG  . ARG A 1 183 ? 122.514 109.514 65.871  1.00 309.48 ? 182 ARG A CG  1 
ATOM   156   C CD  . ARG A 1 183 ? 121.928 109.126 64.520  1.00 312.59 ? 182 ARG A CD  1 
ATOM   157   N NE  . ARG A 1 183 ? 121.340 110.290 63.849  1.00 333.69 ? 182 ARG A NE  1 
ATOM   158   C CZ  . ARG A 1 183 ? 121.680 110.772 62.647  1.00 311.89 ? 182 ARG A CZ  1 
ATOM   159   N NH1 . ARG A 1 183 ? 121.257 111.973 62.275  1.00 239.10 ? 182 ARG A NH1 1 
ATOM   160   N NH2 . ARG A 1 183 ? 122.448 110.070 61.824  1.00 307.64 ? 182 ARG A NH2 1 
ATOM   161   N N   . TRP A 1 184 ? 126.291 109.743 67.264  1.00 166.93 ? 183 TRP A N   1 
ATOM   162   C CA  . TRP A 1 184 ? 127.215 108.864 67.970  1.00 202.51 ? 183 TRP A CA  1 
ATOM   163   C C   . TRP A 1 184 ? 127.478 109.330 69.413  1.00 225.71 ? 183 TRP A C   1 
ATOM   164   O O   . TRP A 1 184 ? 127.448 108.518 70.351  1.00 262.43 ? 183 TRP A O   1 
ATOM   165   C CB  . TRP A 1 184 ? 128.537 108.772 67.211  1.00 241.34 ? 183 TRP A CB  1 
ATOM   166   C CG  . TRP A 1 184 ? 129.554 107.891 67.891  1.00 282.97 ? 183 TRP A CG  1 
ATOM   167   C CD1 . TRP A 1 184 ? 130.595 108.273 68.697  1.00 209.16 ? 183 TRP A CD1 1 
ATOM   168   C CD2 . TRP A 1 184 ? 129.612 106.448 67.803  1.00 350.47 ? 183 TRP A CD2 1 
ATOM   169   N NE1 . TRP A 1 184 ? 131.295 107.171 69.111  1.00 239.89 ? 183 TRP A NE1 1 
ATOM   170   C CE2 . TRP A 1 184 ? 130.721 106.039 68.582  1.00 336.78 ? 183 TRP A CE2 1 
ATOM   171   C CE3 . TRP A 1 184 ? 128.848 105.464 67.147  1.00 351.56 ? 183 TRP A CE3 1 
ATOM   172   C CZ2 . TRP A 1 184 ? 131.071 104.690 68.717  1.00 359.29 ? 183 TRP A CZ2 1 
ATOM   173   C CZ3 . TRP A 1 184 ? 129.197 104.134 67.284  1.00 328.56 ? 183 TRP A CZ3 1 
ATOM   174   C CH2 . TRP A 1 184 ? 130.297 103.754 68.058  1.00 327.96 ? 183 TRP A CH2 1 
ATOM   175   N N   . ALA A 1 185 ? 127.736 110.636 69.596  1.00 205.06 ? 184 ALA A N   1 
ATOM   176   C CA  . ALA A 1 185 ? 127.960 111.198 70.923  1.00 265.88 ? 184 ALA A CA  1 
ATOM   177   C C   . ALA A 1 185 ? 126.747 110.971 71.842  1.00 245.61 ? 184 ALA A C   1 
ATOM   178   O O   . ALA A 1 185 ? 126.931 110.494 72.961  1.00 250.05 ? 184 ALA A O   1 
ATOM   179   C CB  . ALA A 1 185 ? 128.329 112.662 70.825  1.00 309.92 ? 184 ALA A CB  1 
ATOM   180   N N   . LEU A 1 186 ? 125.522 111.282 71.386  1.00 210.93 ? 185 LEU A N   1 
ATOM   181   C CA  . LEU A 1 186 ? 124.329 111.098 72.214  1.00 198.77 ? 185 LEU A CA  1 
ATOM   182   C C   . LEU A 1 186 ? 124.097 109.629 72.562  1.00 178.26 ? 185 LEU A C   1 
ATOM   183   O O   . LEU A 1 186 ? 123.726 109.361 73.704  1.00 249.49 ? 185 LEU A O   1 
ATOM   184   C CB  . LEU A 1 186 ? 123.093 111.684 71.533  1.00 226.85 ? 185 LEU A CB  1 
ATOM   185   C CG  . LEU A 1 186 ? 123.045 113.217 71.488  1.00 291.77 ? 185 LEU A CG  1 
ATOM   186   C CD1 . LEU A 1 186 ? 121.856 113.695 70.667  1.00 386.45 ? 185 LEU A CD1 1 
ATOM   187   C CD2 . LEU A 1 186 ? 122.991 113.848 72.874  1.00 237.85 ? 185 LEU A CD2 1 
ATOM   188   N N   . LEU A 1 187 ? 124.328 108.712 71.613  1.00 154.85 ? 186 LEU A N   1 
ATOM   189   C CA  . LEU A 1 187 ? 124.251 107.273 71.867  1.00 226.32 ? 186 LEU A CA  1 
ATOM   190   C C   . LEU A 1 187 ? 125.200 106.893 73.014  1.00 189.50 ? 186 LEU A C   1 
ATOM   191   O O   . LEU A 1 187 ? 124.749 106.282 73.995  1.00 281.46 ? 186 LEU A O   1 
ATOM   192   C CB  . LEU A 1 187 ? 124.553 106.491 70.571  1.00 305.71 ? 186 LEU A CB  1 
ATOM   193   C CG  . LEU A 1 187 ? 124.351 104.961 70.529  1.00 297.35 ? 186 LEU A CG  1 
ATOM   194   C CD1 . LEU A 1 187 ? 125.339 104.174 71.426  1.00 199.85 ? 186 LEU A CD1 1 
ATOM   195   C CD2 . LEU A 1 187 ? 122.901 104.594 70.847  1.00 317.78 ? 186 LEU A CD2 1 
ATOM   196   N N   . LEU A 1 188 ? 126.484 107.254 72.912  1.00 146.08 ? 187 LEU A N   1 
ATOM   197   C CA  . LEU A 1 188 ? 127.431 106.797 73.916  1.00 220.26 ? 187 LEU A CA  1 
ATOM   198   C C   . LEU A 1 188 ? 127.241 107.558 75.238  1.00 204.95 ? 187 LEU A C   1 
ATOM   199   O O   . LEU A 1 188 ? 127.429 106.955 76.297  1.00 254.45 ? 187 LEU A O   1 
ATOM   200   C CB  . LEU A 1 188 ? 128.856 106.888 73.370  1.00 278.80 ? 187 LEU A CB  1 
ATOM   201   C CG  . LEU A 1 188 ? 129.920 106.282 74.284  1.00 295.64 ? 187 LEU A CG  1 
ATOM   202   C CD1 . LEU A 1 188 ? 129.665 104.801 74.544  1.00 228.84 ? 187 LEU A CD1 1 
ATOM   203   C CD2 . LEU A 1 188 ? 131.312 106.476 73.702  1.00 362.82 ? 187 LEU A CD2 1 
ATOM   204   N N   . LEU A 1 189 ? 126.855 108.846 75.172  1.00 201.25 ? 188 LEU A N   1 
ATOM   205   C CA  . LEU A 1 189 ? 126.512 109.629 76.365  1.00 248.13 ? 188 LEU A CA  1 
ATOM   206   C C   . LEU A 1 189 ? 125.384 108.974 77.179  1.00 265.94 ? 188 LEU A C   1 
ATOM   207   O O   . LEU A 1 189 ? 125.517 108.847 78.397  1.00 224.09 ? 188 LEU A O   1 
ATOM   208   C CB  . LEU A 1 189 ? 126.130 111.056 75.946  1.00 258.74 ? 188 LEU A CB  1 
ATOM   209   C CG  . LEU A 1 189 ? 125.556 111.970 77.032  1.00 325.55 ? 188 LEU A CG  1 
ATOM   210   C CD1 . LEU A 1 189 ? 126.562 112.205 78.150  1.00 396.08 ? 188 LEU A CD1 1 
ATOM   211   C CD2 . LEU A 1 189 ? 125.119 113.297 76.439  1.00 362.84 ? 188 LEU A CD2 1 
ATOM   212   N N   . PHE A 1 190 ? 124.288 108.574 76.513  1.00 254.34 ? 189 PHE A N   1 
ATOM   213   C CA  . PHE A 1 190 ? 123.198 107.844 77.153  1.00 193.83 ? 189 PHE A CA  1 
ATOM   214   C C   . PHE A 1 190 ? 123.692 106.530 77.737  1.00 173.21 ? 189 PHE A C   1 
ATOM   215   O O   . PHE A 1 190 ? 123.399 106.257 78.908  1.00 296.70 ? 189 PHE A O   1 
ATOM   216   C CB  . PHE A 1 190 ? 122.087 107.536 76.163  1.00 247.37 ? 189 PHE A CB  1 
ATOM   217   C CG  . PHE A 1 190 ? 121.071 106.484 76.547  1.00 252.23 ? 189 PHE A CG  1 
ATOM   218   C CD1 . PHE A 1 190 ? 121.319 105.117 76.387  1.00 140.47 ? 189 PHE A CD1 1 
ATOM   219   C CD2 . PHE A 1 190 ? 119.847 106.887 77.057  1.00 296.11 ? 189 PHE A CD2 1 
ATOM   220   C CE1 . PHE A 1 190 ? 120.348 104.193 76.731  1.00 219.07 ? 189 PHE A CE1 1 
ATOM   221   C CE2 . PHE A 1 190 ? 118.870 105.961 77.389  1.00 248.58 ? 189 PHE A CE2 1 
ATOM   222   C CZ  . PHE A 1 190 ? 119.129 104.614 77.230  1.00 292.35 ? 189 PHE A CZ  1 
ATOM   223   N N   . TRP A 1 191 ? 124.444 105.747 76.954  1.00 139.57 ? 190 TRP A N   1 
ATOM   224   C CA  . TRP A 1 191 ? 124.774 104.399 77.379  1.00 165.09 ? 190 TRP A CA  1 
ATOM   225   C C   . TRP A 1 191 ? 125.790 104.390 78.546  1.00 204.46 ? 190 TRP A C   1 
ATOM   226   O O   . TRP A 1 191 ? 125.670 103.570 79.462  1.00 220.93 ? 190 TRP A O   1 
ATOM   227   C CB  . TRP A 1 191 ? 125.244 103.653 76.145  1.00 190.27 ? 190 TRP A CB  1 
ATOM   228   C CG  . TRP A 1 191 ? 125.255 102.179 76.324  1.00 237.02 ? 190 TRP A CG  1 
ATOM   229   C CD1 . TRP A 1 191 ? 126.295 101.341 76.604  1.00 297.91 ? 190 TRP A CD1 1 
ATOM   230   C CD2 . TRP A 1 191 ? 124.080 101.376 76.211  1.00 226.68 ? 190 TRP A CD2 1 
ATOM   231   N NE1 . TRP A 1 191 ? 125.838 100.048 76.662  1.00 308.39 ? 190 TRP A NE1 1 
ATOM   232   C CE2 . TRP A 1 191 ? 124.483 100.036 76.430  1.00 311.32 ? 190 TRP A CE2 1 
ATOM   233   C CE3 . TRP A 1 191 ? 122.747 101.680 75.952  1.00 158.27 ? 190 TRP A CE3 1 
ATOM   234   C CZ2 . TRP A 1 191 ? 123.571 98.981  76.390  1.00 325.96 ? 190 TRP A CZ2 1 
ATOM   235   C CZ3 . TRP A 1 191 ? 121.851 100.632 75.907  1.00 266.99 ? 190 TRP A CZ3 1 
ATOM   236   C CH2 . TRP A 1 191 ? 122.256 99.305  76.122  1.00 321.48 ? 190 TRP A CH2 1 
ATOM   237   N N   . LEU A 1 192 ? 126.770 105.306 78.540  1.00 186.94 ? 191 LEU A N   1 
ATOM   238   C CA  . LEU A 1 192 ? 127.626 105.495 79.699  1.00 241.20 ? 191 LEU A CA  1 
ATOM   239   C C   . LEU A 1 192 ? 126.833 106.114 80.854  1.00 216.71 ? 191 LEU A C   1 
ATOM   240   O O   . LEU A 1 192 ? 127.134 105.823 81.998  1.00 216.65 ? 191 LEU A O   1 
ATOM   241   C CB  . LEU A 1 192 ? 128.835 106.365 79.326  1.00 363.55 ? 191 LEU A CB  1 
ATOM   242   C CG  . LEU A 1 192 ? 129.867 105.758 78.364  1.00 416.84 ? 191 LEU A CG  1 
ATOM   243   C CD1 . LEU A 1 192 ? 130.984 106.761 78.112  1.00 473.13 ? 191 LEU A CD1 1 
ATOM   244   C CD2 . LEU A 1 192 ? 130.461 104.446 78.880  1.00 366.45 ? 191 LEU A CD2 1 
ATOM   245   N N   . GLY A 1 193 ? 125.834 106.964 80.591  1.00 213.15 ? 192 GLY A N   1 
ATOM   246   C CA  . GLY A 1 193 ? 124.928 107.455 81.633  1.00 250.28 ? 192 GLY A CA  1 
ATOM   247   C C   . GLY A 1 193 ? 124.175 106.350 82.391  1.00 219.23 ? 192 GLY A C   1 
ATOM   248   O O   . GLY A 1 193 ? 124.090 106.384 83.616  1.00 164.24 ? 192 GLY A O   1 
ATOM   249   N N   . TRP A 1 194 ? 123.639 105.363 81.659  1.00 230.75 ? 193 TRP A N   1 
ATOM   250   C CA  . TRP A 1 194 ? 123.004 104.188 82.255  1.00 162.16 ? 193 TRP A CA  1 
ATOM   251   C C   . TRP A 1 194 ? 124.036 103.323 82.985  1.00 135.46 ? 193 TRP A C   1 
ATOM   252   O O   . TRP A 1 194 ? 123.729 102.883 84.075  1.00 173.29 ? 193 TRP A O   1 
ATOM   253   C CB  . TRP A 1 194 ? 122.288 103.440 81.148  1.00 169.21 ? 193 TRP A CB  1 
ATOM   254   C CG  . TRP A 1 194 ? 121.619 102.113 81.352  1.00 161.56 ? 193 TRP A CG  1 
ATOM   255   C CD1 . TRP A 1 194 ? 120.273 101.966 81.238  1.00 154.36 ? 193 TRP A CD1 1 
ATOM   256   C CD2 . TRP A 1 194 ? 122.155 100.791 81.576  1.00 138.05 ? 193 TRP A CD2 1 
ATOM   257   N NE1 . TRP A 1 194 ? 119.900 100.660 81.394  1.00 128.35 ? 193 TRP A NE1 1 
ATOM   258   C CE2 . TRP A 1 194 ? 121.039 99.916  81.599  1.00 164.14 ? 193 TRP A CE2 1 
ATOM   259   C CE3 . TRP A 1 194 ? 123.428 100.240 81.759  1.00 119.58 ? 193 TRP A CE3 1 
ATOM   260   C CZ2 . TRP A 1 194 ? 121.202 98.540  81.811  1.00 204.50 ? 193 TRP A CZ2 1 
ATOM   261   C CZ3 . TRP A 1 194 ? 123.581 98.883  81.949  1.00 168.43 ? 193 TRP A CZ3 1 
ATOM   262   C CH2 . TRP A 1 194 ? 122.477 98.037  81.968  1.00 184.44 ? 193 TRP A CH2 1 
ATOM   263   N N   . LEU A 1 195 ? 125.239 103.103 82.440  1.00 131.00 ? 194 LEU A N   1 
ATOM   264   C CA  . LEU A 1 195 ? 126.282 102.390 83.169  1.00 167.52 ? 194 LEU A CA  1 
ATOM   265   C C   . LEU A 1 195 ? 126.735 103.158 84.409  1.00 176.75 ? 194 LEU A C   1 
ATOM   266   O O   . LEU A 1 195 ? 127.081 102.531 85.410  1.00 243.54 ? 194 LEU A O   1 
ATOM   267   C CB  . LEU A 1 195 ? 127.461 102.105 82.236  1.00 223.35 ? 194 LEU A CB  1 
ATOM   268   C CG  . LEU A 1 195 ? 127.273 100.863 81.370  1.00 289.74 ? 194 LEU A CG  1 
ATOM   269   C CD1 . LEU A 1 195 ? 128.302 100.790 80.241  1.00 388.40 ? 194 LEU A CD1 1 
ATOM   270   C CD2 . LEU A 1 195 ? 127.304 99.604  82.247  1.00 215.59 ? 194 LEU A CD2 1 
ATOM   271   N N   . GLY A 1 196 ? 126.731 104.495 84.354  1.00 158.24 ? 195 GLY A N   1 
ATOM   272   C CA  . GLY A 1 196 ? 126.940 105.330 85.538  1.00 250.74 ? 195 GLY A CA  1 
ATOM   273   C C   . GLY A 1 196 ? 125.865 105.150 86.621  1.00 251.22 ? 195 GLY A C   1 
ATOM   274   O O   . GLY A 1 196 ? 126.190 104.989 87.803  1.00 192.29 ? 195 GLY A O   1 
ATOM   275   N N   . MET A 1 197 ? 124.592 105.176 86.204  1.00 243.33 ? 196 MET A N   1 
ATOM   276   C CA  . MET A 1 197 ? 123.466 104.973 87.108  1.00 181.87 ? 196 MET A CA  1 
ATOM   277   C C   . MET A 1 197 ? 123.509 103.548 87.694  1.00 142.32 ? 196 MET A C   1 
ATOM   278   O O   . MET A 1 197 ? 123.171 103.423 88.864  1.00 194.28 ? 196 MET A O   1 
ATOM   279   C CB  . MET A 1 197 ? 122.142 105.253 86.376  1.00 227.66 ? 196 MET A CB  1 
ATOM   280   C CG  . MET A 1 197 ? 120.853 104.849 87.139  1.00 222.77 ? 196 MET A CG  1 
ATOM   281   S SD  . MET A 1 197 ? 119.279 105.091 86.255  1.00 265.50 ? 196 MET A SD  1 
ATOM   282   C CE  . MET A 1 197 ? 119.187 106.886 86.194  1.00 283.91 ? 196 MET A CE  1 
ATOM   283   N N   . LEU A 1 198 ? 123.932 102.492 86.946  1.00 115.53 ? 197 LEU A N   1 
ATOM   284   C CA  . LEU A 1 198 ? 124.179 101.163 87.510  1.00 135.81 ? 197 LEU A CA  1 
ATOM   285   C C   . LEU A 1 198 ? 125.316 101.202 88.540  1.00 153.28 ? 197 LEU A C   1 
ATOM   286   O O   . LEU A 1 198 ? 125.149 100.625 89.626  1.00 209.64 ? 197 LEU A O   1 
ATOM   287   C CB  . LEU A 1 198 ? 124.469 100.089 86.455  1.00 140.81 ? 197 LEU A CB  1 
ATOM   288   C CG  . LEU A 1 198 ? 124.769 98.688  87.040  1.00 168.63 ? 197 LEU A CG  1 
ATOM   289   C CD1 . LEU A 1 198 ? 124.100 97.582  86.238  1.00 291.43 ? 197 LEU A CD1 1 
ATOM   290   C CD2 . LEU A 1 198 ? 126.264 98.387  87.130  1.00 148.54 ? 197 LEU A CD2 1 
ATOM   291   N N   . ALA A 1 199 ? 126.436 101.862 88.237  1.00 148.62 ? 198 ALA A N   1 
ATOM   292   C CA  . ALA A 1 199 ? 127.506 101.919 89.208  1.00 177.76 ? 198 ALA A CA  1 
ATOM   293   C C   . ALA A 1 199 ? 127.013 102.653 90.464  1.00 197.43 ? 198 ALA A C   1 
ATOM   294   O O   . ALA A 1 199 ? 127.375 102.245 91.569  1.00 272.47 ? 198 ALA A O   1 
ATOM   295   C CB  . ALA A 1 199 ? 128.717 102.565 88.580  1.00 257.11 ? 198 ALA A CB  1 
ATOM   296   N N   . GLY A 1 200 ? 126.197 103.720 90.307  1.00 167.05 ? 199 GLY A N   1 
ATOM   297   C CA  . GLY A 1 200 ? 125.577 104.438 91.420  1.00 200.16 ? 199 GLY A CA  1 
ATOM   298   C C   . GLY A 1 200 ? 124.729 103.533 92.317  1.00 176.03 ? 199 GLY A C   1 
ATOM   299   O O   . GLY A 1 200 ? 124.839 103.572 93.530  1.00 204.35 ? 199 GLY A O   1 
ATOM   300   N N   . ALA A 1 201 ? 123.879 102.713 91.713  1.00 184.65 ? 200 ALA A N   1 
ATOM   301   C CA  . ALA A 1 201 ? 123.063 101.781 92.468  1.00 173.85 ? 200 ALA A CA  1 
ATOM   302   C C   . ALA A 1 201 ? 123.972 100.728 93.113  1.00 162.39 ? 200 ALA A C   1 
ATOM   303   O O   . ALA A 1 201 ? 123.727 100.384 94.256  1.00 251.54 ? 200 ALA A O   1 
ATOM   304   C CB  . ALA A 1 201 ? 121.957 101.199 91.587  1.00 153.86 ? 200 ALA A CB  1 
ATOM   305   N N   . VAL A 1 202 ? 125.009 100.207 92.441  1.00 119.40 ? 201 VAL A N   1 
ATOM   306   C CA  . VAL A 1 202 ? 125.838 99.174  93.059  1.00 158.30 ? 201 VAL A CA  1 
ATOM   307   C C   . VAL A 1 202 ? 126.616 99.758  94.241  1.00 168.25 ? 201 VAL A C   1 
ATOM   308   O O   . VAL A 1 202 ? 126.819 99.048  95.223  1.00 195.04 ? 201 VAL A O   1 
ATOM   309   C CB  . VAL A 1 202 ? 126.750 98.470  92.045  1.00 232.31 ? 201 VAL A CB  1 
ATOM   310   C CG1 . VAL A 1 202 ? 127.815 97.599  92.705  1.00 239.76 ? 201 VAL A CG1 1 
ATOM   311   C CG2 . VAL A 1 202 ? 125.914 97.632  91.082  1.00 295.33 ? 201 VAL A CG2 1 
ATOM   312   N N   . VAL A 1 203 ? 127.018 101.032 94.165  1.00 162.28 ? 202 VAL A N   1 
ATOM   313   C CA  . VAL A 1 203 ? 127.580 101.731 95.319  1.00 181.40 ? 202 VAL A CA  1 
ATOM   314   C C   . VAL A 1 203 ? 126.568 101.802 96.469  1.00 180.49 ? 202 VAL A C   1 
ATOM   315   O O   . VAL A 1 203 ? 126.953 101.414 97.571  1.00 215.63 ? 202 VAL A O   1 
ATOM   316   C CB  . VAL A 1 203 ? 128.120 103.123 94.929  1.00 255.89 ? 202 VAL A CB  1 
ATOM   317   C CG1 . VAL A 1 203 ? 128.227 104.117 96.095  1.00 279.93 ? 202 VAL A CG1 1 
ATOM   318   C CG2 . VAL A 1 203 ? 129.450 102.962 94.206  1.00 333.73 ? 202 VAL A CG2 1 
ATOM   319   N N   . ILE A 1 204 ? 125.323 102.278 96.245  1.00 165.33 ? 203 ILE A N   1 
ATOM   320   C CA  . ILE A 1 204 ? 124.322 102.405 97.311  1.00 170.35 ? 203 ILE A CA  1 
ATOM   321   C C   . ILE A 1 204 ? 124.090 101.040 97.981  1.00 144.46 ? 203 ILE A C   1 
ATOM   322   O O   . ILE A 1 204 ? 124.072 100.964 99.195  1.00 217.25 ? 203 ILE A O   1 
ATOM   323   C CB  . ILE A 1 204 ? 123.013 103.077 96.822  1.00 177.10 ? 203 ILE A CB  1 
ATOM   324   C CG1 . ILE A 1 204 ? 123.265 104.545 96.484  1.00 232.16 ? 203 ILE A CG1 1 
ATOM   325   C CG2 . ILE A 1 204 ? 121.871 102.966 97.818  1.00 201.89 ? 203 ILE A CG2 1 
ATOM   326   C CD1 . ILE A 1 204 ? 122.108 105.230 95.800  1.00 254.24 ? 203 ILE A CD1 1 
ATOM   327   N N   . ILE A 1 205 ? 123.955 99.975  97.214  1.00 98.98  ? 204 ILE A N   1 
ATOM   328   C CA  . ILE A 1 205 ? 123.724 98.640  97.748  1.00 117.22 ? 204 ILE A CA  1 
ATOM   329   C C   . ILE A 1 205 ? 124.918 98.112  98.571  1.00 148.85 ? 204 ILE A C   1 
ATOM   330   O O   . ILE A 1 205 ? 124.718 97.235  99.429  1.00 263.12 ? 204 ILE A O   1 
ATOM   331   C CB  . ILE A 1 205 ? 123.369 97.715  96.549  1.00 163.98 ? 204 ILE A CB  1 
ATOM   332   C CG1 . ILE A 1 205 ? 122.029 98.120  95.894  1.00 133.78 ? 204 ILE A CG1 1 
ATOM   333   C CG2 . ILE A 1 205 ? 123.446 96.210  96.866  1.00 138.20 ? 204 ILE A CG2 1 
ATOM   334   C CD1 . ILE A 1 205 ? 120.823 98.019  96.758  1.00 140.39 ? 204 ILE A CD1 1 
ATOM   335   N N   . VAL A 1 206 ? 126.156 98.602  98.339  1.00 133.94 ? 205 VAL A N   1 
ATOM   336   C CA  . VAL A 1 206 ? 127.292 98.252  99.197  1.00 177.31 ? 205 VAL A CA  1 
ATOM   337   C C   . VAL A 1 206 ? 127.414 99.182  100.413 1.00 187.86 ? 205 VAL A C   1 
ATOM   338   O O   . VAL A 1 206 ? 127.765 98.718  101.499 1.00 189.14 ? 205 VAL A O   1 
ATOM   339   C CB  . VAL A 1 206 ? 128.588 98.167  98.376  1.00 220.00 ? 205 VAL A CB  1 
ATOM   340   C CG1 . VAL A 1 206 ? 129.854 98.193  99.231  1.00 260.92 ? 205 VAL A CG1 1 
ATOM   341   C CG2 . VAL A 1 206 ? 128.537 96.906  97.514  1.00 221.96 ? 205 VAL A CG2 1 
ATOM   342   N N   . ARG A 1 207 ? 127.116 100.473 100.246 1.00 221.59 ? 206 ARG A N   1 
ATOM   343   C CA  . ARG A 1 207 ? 127.179 101.448 101.333 1.00 249.60 ? 206 ARG A CA  1 
ATOM   344   C C   . ARG A 1 207 ? 126.012 101.317 102.325 1.00 233.49 ? 206 ARG A C   1 
ATOM   345   O O   . ARG A 1 207 ? 126.107 101.822 103.440 1.00 266.08 ? 206 ARG A O   1 
ATOM   346   C CB  . ARG A 1 207 ? 127.219 102.867 100.748 1.00 299.22 ? 206 ARG A CB  1 
ATOM   347   C CG  . ARG A 1 207 ? 128.491 103.201 99.975  1.00 367.56 ? 206 ARG A CG  1 
ATOM   348   C CD  . ARG A 1 207 ? 129.708 103.358 100.884 1.00 386.98 ? 206 ARG A CD  1 
ATOM   349   N NE  . ARG A 1 207 ? 130.955 103.607 100.156 1.00 433.20 ? 206 ARG A NE  1 
ATOM   350   C CZ  . ARG A 1 207 ? 131.375 104.791 99.703  1.00 420.45 ? 206 ARG A CZ  1 
ATOM   351   N NH1 . ARG A 1 207 ? 132.438 104.859 98.913  1.00 387.01 ? 206 ARG A NH1 1 
ATOM   352   N NH2 . ARG A 1 207 ? 130.734 105.904 100.029 1.00 366.87 ? 206 ARG A NH2 1 
ATOM   353   N N   . ALA A 1 208 ? 124.915 100.648 101.932 1.00 224.52 ? 207 ALA A N   1 
ATOM   354   C CA  . ALA A 1 208 ? 123.748 100.441 102.775 1.00 244.52 ? 207 ALA A CA  1 
ATOM   355   C C   . ALA A 1 208 ? 124.063 99.578  104.005 1.00 237.71 ? 207 ALA A C   1 
ATOM   356   O O   . ALA A 1 208 ? 124.834 98.600  103.894 1.00 135.70 ? 207 ALA A O   1 
ATOM   357   C CB  . ALA A 1 208 ? 122.644 99.811  101.955 1.00 268.40 ? 207 ALA A CB  1 
ATOM   358   N N   . PRO A 1 209 ? 123.461 99.915  105.190 1.00 217.90 ? 208 PRO A N   1 
ATOM   359   C CA  . PRO A 1 209 ? 123.652 99.130  106.412 1.00 176.24 ? 208 PRO A CA  1 
ATOM   360   C C   . PRO A 1 209 ? 123.178 97.700  106.218 1.00 140.49 ? 208 PRO A C   1 
ATOM   361   O O   . PRO A 1 209 ? 121.994 97.524  105.906 1.00 183.34 ? 208 PRO A O   1 
ATOM   362   C CB  . PRO A 1 209 ? 122.748 99.836  107.446 1.00 248.56 ? 208 PRO A CB  1 
ATOM   363   C CG  . PRO A 1 209 ? 122.521 101.244 106.912 1.00 238.93 ? 208 PRO A CG  1 
ATOM   364   C CD  . PRO A 1 209 ? 122.564 101.080 105.415 1.00 215.56 ? 208 PRO A CD  1 
ATOM   365   N N   . ARG A 1 210 ? 124.064 96.700  106.394 1.00 156.22 ? 209 ARG A N   1 
ATOM   366   C CA  . ARG A 1 210 ? 123.682 95.310  106.147 1.00 198.58 ? 209 ARG A CA  1 
ATOM   367   C C   . ARG A 1 210 ? 122.654 94.839  107.177 1.00 168.08 ? 209 ARG A C   1 
ATOM   368   O O   . ARG A 1 210 ? 122.561 95.414  108.256 1.00 220.37 ? 209 ARG A O   1 
ATOM   369   C CB  . ARG A 1 210 ? 124.898 94.370  106.121 1.00 217.06 ? 209 ARG A CB  1 
ATOM   370   C CG  . ARG A 1 210 ? 125.338 93.974  104.721 1.00 253.12 ? 209 ARG A CG  1 
ATOM   371   C CD  . ARG A 1 210 ? 124.213 93.432  103.841 1.00 280.20 ? 209 ARG A CD  1 
ATOM   372   N NE  . ARG A 1 210 ? 123.666 94.462  102.964 1.00 257.27 ? 209 ARG A NE  1 
ATOM   373   C CZ  . ARG A 1 210 ? 124.341 95.130  102.030 1.00 304.45 ? 209 ARG A CZ  1 
ATOM   374   N NH1 . ARG A 1 210 ? 124.578 96.406  102.262 1.00 352.88 ? 209 ARG A NH1 1 
ATOM   375   N NH2 . ARG A 1 210 ? 124.843 94.556  100.943 1.00 302.77 ? 209 ARG A NH2 1 
ATOM   376   N N   . CYS A 1 211 ? 121.878 93.796  106.860 1.00 188.94 ? 210 CYS A N   1 
ATOM   377   C CA  . CYS A 1 211 ? 120.894 93.312  107.815 1.00 204.44 ? 210 CYS A CA  1 
ATOM   378   C C   . CYS A 1 211 ? 121.567 92.681  109.034 1.00 236.31 ? 210 CYS A C   1 
ATOM   379   O O   . CYS A 1 211 ? 122.704 92.227  108.944 1.00 280.67 ? 210 CYS A O   1 
ATOM   380   C CB  . CYS A 1 211 ? 120.021 92.256  107.163 1.00 209.21 ? 210 CYS A CB  1 
ATOM   381   S SG  . CYS A 1 211 ? 118.279 92.715  107.008 1.00 224.26 ? 210 CYS A SG  1 
ATOM   382   N N   . ARG A 1 212 ? 120.853 92.636  110.169 1.00 188.90 ? 211 ARG A N   1 
ATOM   383   C CA  . ARG A 1 212 ? 121.357 92.006  111.386 1.00 179.09 ? 211 ARG A CA  1 
ATOM   384   C C   . ARG A 1 212 ? 120.827 90.570  111.432 1.00 171.01 ? 211 ARG A C   1 
ATOM   385   O O   . ARG A 1 212 ? 119.611 90.372  111.312 1.00 146.43 ? 211 ARG A O   1 
ATOM   386   C CB  . ARG A 1 212 ? 120.921 92.846  112.593 1.00 283.95 ? 211 ARG A CB  1 
ATOM   387   C CG  . ARG A 1 212 ? 120.974 92.141  113.946 1.00 240.18 ? 211 ARG A CG  1 
ATOM   388   C CD  . ARG A 1 212 ? 119.923 92.717  114.876 1.00 173.36 ? 211 ARG A CD  1 
ATOM   389   N NE  . ARG A 1 212 ? 120.325 93.794  115.762 1.00 230.90 ? 211 ARG A NE  1 
ATOM   390   C CZ  . ARG A 1 212 ? 120.100 93.814  117.065 1.00 215.39 ? 211 ARG A CZ  1 
ATOM   391   N NH1 . ARG A 1 212 ? 119.220 94.710  117.502 1.00 277.64 ? 211 ARG A NH1 1 
ATOM   392   N NH2 . ARG A 1 212 ? 120.662 92.925  117.886 1.00 177.28 ? 211 ARG A NH2 1 
ATOM   393   N N   . GLU A 1 213 ? 121.738 89.590  111.621 1.00 163.15 ? 212 GLU A N   1 
ATOM   394   C CA  . GLU A 1 213 ? 121.394 88.162  111.648 1.00 162.11 ? 212 GLU A CA  1 
ATOM   395   C C   . GLU A 1 213 ? 120.205 87.927  112.580 1.00 146.97 ? 212 GLU A C   1 
ATOM   396   O O   . GLU A 1 213 ? 120.230 88.361  113.740 1.00 296.28 ? 212 GLU A O   1 
ATOM   397   C CB  . GLU A 1 213 ? 122.551 87.294  112.147 1.00 230.07 ? 212 GLU A CB  1 
ATOM   398   C CG  . GLU A 1 213 ? 123.696 87.143  111.159 1.00 336.03 ? 212 GLU A CG  1 
ATOM   399   C CD  . GLU A 1 213 ? 124.645 88.322  111.010 1.00 427.69 ? 212 GLU A CD  1 
ATOM   400   O OE1 . GLU A 1 213 ? 124.650 89.215  111.887 1.00 452.37 ? 212 GLU A OE1 1 
ATOM   401   O OE2 . GLU A 1 213 ? 125.375 88.350  110.007 1.00 486.53 ? 212 GLU A OE2 1 
ATOM   402   N N   . LEU A 1 214 ? 119.135 87.301  112.086 1.00 123.82 ? 213 LEU A N   1 
ATOM   403   C CA  . LEU A 1 214 ? 117.949 87.039  112.906 1.00 127.93 ? 213 LEU A CA  1 
ATOM   404   C C   . LEU A 1 214 ? 118.213 85.776  113.732 1.00 148.66 ? 213 LEU A C   1 
ATOM   405   O O   . LEU A 1 214 ? 118.602 84.750  113.174 1.00 213.76 ? 213 LEU A O   1 
ATOM   406   C CB  . LEU A 1 214 ? 116.738 86.903  111.991 1.00 150.19 ? 213 LEU A CB  1 
ATOM   407   C CG  . LEU A 1 214 ? 115.376 87.209  112.568 1.00 160.68 ? 213 LEU A CG  1 
ATOM   408   C CD1 . LEU A 1 214 ? 114.438 87.581  111.440 1.00 180.77 ? 213 LEU A CD1 1 
ATOM   409   C CD2 . LEU A 1 214 ? 114.826 86.005  113.361 1.00 221.23 ? 213 LEU A CD2 1 
ATOM   410   N N   . PRO A 1 215 ? 118.040 85.819  115.073 1.00 140.81 ? 214 PRO A N   1 
ATOM   411   C CA  . PRO A 1 215 ? 118.428 84.698  115.934 1.00 144.32 ? 214 PRO A CA  1 
ATOM   412   C C   . PRO A 1 215 ? 117.451 83.525  115.797 1.00 169.45 ? 214 PRO A C   1 
ATOM   413   O O   . PRO A 1 215 ? 116.239 83.709  115.775 1.00 179.20 ? 214 PRO A O   1 
ATOM   414   C CB  . PRO A 1 215 ? 118.410 85.346  117.322 1.00 153.72 ? 214 PRO A CB  1 
ATOM   415   C CG  . PRO A 1 215 ? 117.299 86.452  117.221 1.00 155.07 ? 214 PRO A CG  1 
ATOM   416   C CD  . PRO A 1 215 ? 117.490 86.971  115.824 1.00 153.60 ? 214 PRO A CD  1 
ATOM   417   N N   . ALA A 1 216 ? 117.996 82.308  115.692 1.00 260.37 ? 215 ALA A N   1 
ATOM   418   C CA  . ALA A 1 216 ? 117.181 81.103  115.596 1.00 275.01 ? 215 ALA A CA  1 
ATOM   419   C C   . ALA A 1 216 ? 116.495 80.899  116.938 1.00 158.06 ? 215 ALA A C   1 
ATOM   420   O O   . ALA A 1 216 ? 117.200 80.819  117.933 1.00 110.78 ? 215 ALA A O   1 
ATOM   421   C CB  . ALA A 1 216 ? 118.031 79.904  115.240 1.00 369.57 ? 215 ALA A CB  1 
ATOM   422   N N   . GLN A 1 217 ? 115.158 80.843  116.952 1.00 140.17 ? 216 GLN A N   1 
ATOM   423   C CA  . GLN A 1 217 ? 114.417 80.964  118.200 1.00 173.79 ? 216 GLN A CA  1 
ATOM   424   C C   . GLN A 1 217 ? 113.580 79.687  118.382 1.00 137.70 ? 216 GLN A C   1 
ATOM   425   O O   . GLN A 1 217 ? 112.813 79.276  117.524 1.00 130.03 ? 216 GLN A O   1 
ATOM   426   C CB  . GLN A 1 217 ? 113.612 82.275  118.243 1.00 192.09 ? 216 GLN A CB  1 
ATOM   427   C CG  . GLN A 1 217 ? 112.574 82.401  117.142 1.00 227.22 ? 216 GLN A CG  1 
ATOM   428   C CD  . GLN A 1 217 ? 111.814 83.697  117.274 1.00 266.87 ? 216 GLN A CD  1 
ATOM   429   O OE1 . GLN A 1 217 ? 111.823 84.368  118.320 1.00 137.47 ? 216 GLN A OE1 1 
ATOM   430   N NE2 . GLN A 1 217 ? 111.164 84.081  116.179 1.00 326.63 ? 216 GLN A NE2 1 
ATOM   431   N N   . LYS A 1 218 ? 113.728 79.095  119.561 1.00 134.25 ? 217 LYS A N   1 
ATOM   432   C CA  . LYS A 1 218 ? 112.916 77.999  120.059 1.00 132.61 ? 217 LYS A CA  1 
ATOM   433   C C   . LYS A 1 218 ? 111.464 78.447  120.216 1.00 104.32 ? 217 LYS A C   1 
ATOM   434   O O   . LYS A 1 218 ? 111.154 79.620  120.304 1.00 122.59 ? 217 LYS A O   1 
ATOM   435   C CB  . LYS A 1 218 ? 113.560 77.539  121.380 1.00 155.43 ? 217 LYS A CB  1 
ATOM   436   C CG  . LYS A 1 218 ? 115.047 77.155  121.292 1.00 164.27 ? 217 LYS A CG  1 
ATOM   437   C CD  . LYS A 1 218 ? 115.313 76.342  120.044 1.00 194.53 ? 217 LYS A CD  1 
ATOM   438   C CE  . LYS A 1 218 ? 116.595 75.559  119.937 1.00 232.93 ? 217 LYS A CE  1 
ATOM   439   N NZ  . LYS A 1 218 ? 116.619 74.913  118.598 1.00 293.64 ? 217 LYS A NZ  1 
ATOM   440   N N   . TRP A 1 219 ? 110.554 77.505  120.282 1.00 84.38  ? 218 TRP A N   1 
ATOM   441   C CA  . TRP A 1 219 ? 109.147 77.870  120.303 1.00 97.26  ? 218 TRP A CA  1 
ATOM   442   C C   . TRP A 1 219 ? 108.715 78.718  121.490 1.00 86.73  ? 218 TRP A C   1 
ATOM   443   O O   . TRP A 1 219 ? 107.910 79.633  121.392 1.00 81.03  ? 218 TRP A O   1 
ATOM   444   C CB  . TRP A 1 219 ? 108.286 76.625  120.301 1.00 127.48 ? 218 TRP A CB  1 
ATOM   445   C CG  . TRP A 1 219 ? 108.520 75.611  121.374 1.00 94.16  ? 218 TRP A CG  1 
ATOM   446   C CD1 . TRP A 1 219 ? 109.308 74.493  121.337 1.00 170.13 ? 218 TRP A CD1 1 
ATOM   447   C CD2 . TRP A 1 219 ? 107.853 75.575  122.619 1.00 68.05  ? 218 TRP A CD2 1 
ATOM   448   N NE1 . TRP A 1 219 ? 109.206 73.795  122.510 1.00 131.39 ? 218 TRP A NE1 1 
ATOM   449   C CE2 . TRP A 1 219 ? 108.311 74.440  123.307 1.00 85.76  ? 218 TRP A CE2 1 
ATOM   450   C CE3 . TRP A 1 219 ? 106.920 76.401  123.212 1.00 89.64  ? 218 TRP A CE3 1 
ATOM   451   C CZ2 . TRP A 1 219 ? 107.851 74.113  124.572 1.00 138.78 ? 218 TRP A CZ2 1 
ATOM   452   C CZ3 . TRP A 1 219 ? 106.467 76.066  124.472 1.00 122.89 ? 218 TRP A CZ3 1 
ATOM   453   C CH2 . TRP A 1 219 ? 106.918 74.946  125.146 1.00 105.48 ? 218 TRP A CH2 1 
ATOM   454   N N   . TRP A 1 220 ? 109.313 78.441  122.620 1.00 90.80  ? 219 TRP A N   1 
ATOM   455   C CA  . TRP A 1 220 ? 108.981 79.181  123.809 1.00 65.54  ? 219 TRP A CA  1 
ATOM   456   C C   . TRP A 1 220 ? 109.518 80.591  123.802 1.00 48.20  ? 219 TRP A C   1 
ATOM   457   O O   . TRP A 1 220 ? 109.132 81.363  124.685 1.00 129.13 ? 219 TRP A O   1 
ATOM   458   C CB  . TRP A 1 220 ? 109.498 78.422  125.055 1.00 69.44  ? 219 TRP A CB  1 
ATOM   459   C CG  . TRP A 1 220 ? 110.976 78.269  125.177 1.00 61.22  ? 219 TRP A CG  1 
ATOM   460   C CD1 . TRP A 1 220 ? 111.811 79.137  125.736 1.00 75.33  ? 219 TRP A CD1 1 
ATOM   461   C CD2 . TRP A 1 220 ? 111.774 77.157  124.778 1.00 90.07  ? 219 TRP A CD2 1 
ATOM   462   N NE1 . TRP A 1 220 ? 113.079 78.657  125.698 1.00 106.26 ? 219 TRP A NE1 1 
ATOM   463   C CE2 . TRP A 1 220 ? 113.085 77.440  125.122 1.00 95.03  ? 219 TRP A CE2 1 
ATOM   464   C CE3 . TRP A 1 220 ? 111.513 75.941  124.173 1.00 122.84 ? 219 TRP A CE3 1 
ATOM   465   C CZ2 . TRP A 1 220 ? 114.134 76.567  124.886 1.00 159.27 ? 219 TRP A CZ2 1 
ATOM   466   C CZ3 . TRP A 1 220 ? 112.533 75.063  123.928 1.00 139.08 ? 219 TRP A CZ3 1 
ATOM   467   C CH2 . TRP A 1 220 ? 113.831 75.369  124.292 1.00 152.51 ? 219 TRP A CH2 1 
ATOM   468   N N   . HIS A 1 221 ? 110.405 80.975  122.925 1.00 43.81  ? 220 HIS A N   1 
ATOM   469   C CA  . HIS A 1 221 ? 110.602 82.402  122.830 1.00 61.92  ? 220 HIS A CA  1 
ATOM   470   C C   . HIS A 1 221 ? 109.399 83.125  122.213 1.00 68.20  ? 220 HIS A C   1 
ATOM   471   O O   . HIS A 1 221 ? 109.227 84.299  122.456 1.00 91.76  ? 220 HIS A O   1 
ATOM   472   C CB  . HIS A 1 221 ? 111.851 82.758  122.022 1.00 93.73  ? 220 HIS A CB  1 
ATOM   473   C CG  . HIS A 1 221 ? 113.116 82.226  122.554 1.00 89.82  ? 220 HIS A CG  1 
ATOM   474   N ND1 . HIS A 1 221 ? 114.318 82.556  121.977 1.00 123.68 ? 220 HIS A ND1 1 
ATOM   475   C CD2 . HIS A 1 221 ? 113.356 81.396  123.581 1.00 68.16  ? 220 HIS A CD2 1 
ATOM   476   C CE1 . HIS A 1 221 ? 115.258 81.897  122.674 1.00 183.39 ? 220 HIS A CE1 1 
ATOM   477   N NE2 . HIS A 1 221 ? 114.693 81.199  123.659 1.00 89.72  ? 220 HIS A NE2 1 
ATOM   478   N N   . THR A 1 222 ? 108.566 82.483  121.406 1.00 67.56  ? 221 THR A N   1 
ATOM   479   C CA  . THR A 1 222 ? 107.673 83.227  120.550 1.00 72.72  ? 221 THR A CA  1 
ATOM   480   C C   . THR A 1 222 ? 106.409 83.705  121.260 1.00 73.53  ? 221 THR A C   1 
ATOM   481   O O   . THR A 1 222 ? 105.526 84.199  120.547 1.00 138.91 ? 221 THR A O   1 
ATOM   482   C CB  . THR A 1 222 ? 107.268 82.367  119.336 1.00 133.46 ? 221 THR A CB  1 
ATOM   483   O OG1 . THR A 1 222 ? 106.508 81.216  119.725 1.00 144.02 ? 221 THR A OG1 1 
ATOM   484   C CG2 . THR A 1 222 ? 108.503 81.952  118.549 1.00 189.49 ? 221 THR A CG2 1 
ATOM   485   N N   . GLY A 1 223 ? 106.274 83.568  122.611 1.00 89.13  ? 222 GLY A N   1 
ATOM   486   C CA  . GLY A 1 223 ? 105.170 84.128  123.419 1.00 80.55  ? 222 GLY A CA  1 
ATOM   487   C C   . GLY A 1 223 ? 104.794 83.208  124.578 1.00 91.21  ? 222 GLY A C   1 
ATOM   488   O O   . GLY A 1 223 ? 105.547 82.263  124.930 1.00 77.16  ? 222 GLY A O   1 
ATOM   489   N N   . ALA A 1 224 ? 103.606 83.477  125.151 1.00 69.88  ? 223 ALA A N   1 
ATOM   490   C CA  . ALA A 1 224 ? 103.376 83.150  126.570 1.00 73.66  ? 223 ALA A CA  1 
ATOM   491   C C   . ALA A 1 224 ? 103.154 81.680  126.874 1.00 47.30  ? 223 ALA A C   1 
ATOM   492   O O   . ALA A 1 224 ? 102.357 81.090  126.180 1.00 103.01 ? 223 ALA A O   1 
ATOM   493   C CB  . ALA A 1 224 ? 102.203 83.950  127.058 1.00 90.10  ? 223 ALA A CB  1 
ATOM   494   N N   . LEU A 1 225 ? 103.764 81.106  127.900 1.00 46.87  ? 224 LEU A N   1 
ATOM   495   C CA  . LEU A 1 225 ? 103.304 79.789  128.366 1.00 66.80  ? 224 LEU A CA  1 
ATOM   496   C C   . LEU A 1 225 ? 102.085 79.994  129.247 1.00 74.97  ? 224 LEU A C   1 
ATOM   497   O O   . LEU A 1 225 ? 101.716 81.153  129.475 1.00 70.00  ? 224 LEU A O   1 
ATOM   498   C CB  . LEU A 1 225 ? 104.336 78.998  129.167 1.00 61.30  ? 224 LEU A CB  1 
ATOM   499   C CG  . LEU A 1 225 ? 105.724 79.026  128.557 1.00 68.78  ? 224 LEU A CG  1 
ATOM   500   C CD1 . LEU A 1 225 ? 106.689 78.097  129.279 1.00 69.63  ? 224 LEU A CD1 1 
ATOM   501   C CD2 . LEU A 1 225 ? 105.633 78.679  127.101 1.00 71.24  ? 224 LEU A CD2 1 
ATOM   502   N N   . TYR A 1 226 ? 101.465 78.891  129.748 1.00 63.32  ? 225 TYR A N   1 
ATOM   503   C CA  . TYR A 1 226 ? 100.184 79.027  130.460 1.00 60.22  ? 225 TYR A CA  1 
ATOM   504   C C   . TYR A 1 226 ? 100.024 77.806  131.368 1.00 44.58  ? 225 TYR A C   1 
ATOM   505   O O   . TYR A 1 226 ? 100.066 76.728  130.880 1.00 67.65  ? 225 TYR A O   1 
ATOM   506   C CB  . TYR A 1 226 ? 99.043  79.296  129.441 1.00 48.93  ? 225 TYR A CB  1 
ATOM   507   C CG  . TYR A 1 226 ? 97.651  79.537  130.022 1.00 67.36  ? 225 TYR A CG  1 
ATOM   508   C CD1 . TYR A 1 226 ? 96.951  78.534  130.731 1.00 60.57  ? 225 TYR A CD1 1 
ATOM   509   C CD2 . TYR A 1 226 ? 97.058  80.806  129.899 1.00 78.78  ? 225 TYR A CD2 1 
ATOM   510   C CE1 . TYR A 1 226 ? 95.699  78.812  131.273 1.00 86.87  ? 225 TYR A CE1 1 
ATOM   511   C CE2 . TYR A 1 226 ? 95.811  81.075  130.450 1.00 90.88  ? 225 TYR A CE2 1 
ATOM   512   C CZ  . TYR A 1 226 ? 95.121  80.076  131.135 1.00 91.15  ? 225 TYR A CZ  1 
ATOM   513   O OH  . TYR A 1 226 ? 93.891  80.302  131.699 1.00 61.70  ? 225 TYR A OH  1 
ATOM   514   N N   . ARG A 1 227 ? 99.797  77.962  132.633 1.00 37.42  ? 226 ARG A N   1 
ATOM   515   C CA  . ARG A 1 227 ? 99.931  76.840  133.510 1.00 53.76  ? 226 ARG A CA  1 
ATOM   516   C C   . ARG A 1 227 ? 98.581  76.494  134.114 1.00 61.32  ? 226 ARG A C   1 
ATOM   517   O O   . ARG A 1 227 ? 97.791  77.354  134.498 1.00 110.46 ? 226 ARG A O   1 
ATOM   518   C CB  . ARG A 1 227 ? 100.818 77.119  134.721 1.00 83.47  ? 226 ARG A CB  1 
ATOM   519   C CG  . ARG A 1 227 ? 102.202 77.601  134.328 1.00 103.46 ? 226 ARG A CG  1 
ATOM   520   C CD  . ARG A 1 227 ? 103.037 77.818  135.590 1.00 108.24 ? 226 ARG A CD  1 
ATOM   521   N NE  . ARG A 1 227 ? 102.682 79.036  136.229 1.00 70.09  ? 226 ARG A NE  1 
ATOM   522   C CZ  . ARG A 1 227 ? 103.529 79.792  136.837 1.00 93.20  ? 226 ARG A CZ  1 
ATOM   523   N NH1 . ARG A 1 227 ? 103.106 80.944  137.349 1.00 124.21 ? 226 ARG A NH1 1 
ATOM   524   N NH2 . ARG A 1 227 ? 104.789 79.354  136.922 1.00 95.15  ? 226 ARG A NH2 1 
ATOM   525   N N   . ILE A 1 228 ? 98.366  75.195  134.264 1.00 81.00  ? 227 ILE A N   1 
ATOM   526   C CA  . ILE A 1 228 ? 97.077  74.627  134.599 1.00 62.70  ? 227 ILE A CA  1 
ATOM   527   C C   . ILE A 1 228 ? 97.347  73.666  135.726 1.00 80.13  ? 227 ILE A C   1 
ATOM   528   O O   . ILE A 1 228 ? 97.593  72.480  135.514 1.00 95.09  ? 227 ILE A O   1 
ATOM   529   C CB  . ILE A 1 228 ? 96.504  74.006  133.322 1.00 55.51  ? 227 ILE A CB  1 
ATOM   530   C CG1 . ILE A 1 228 ? 96.312  75.146  132.292 1.00 58.05  ? 227 ILE A CG1 1 
ATOM   531   C CG2 . ILE A 1 228 ? 95.255  73.263  133.659 1.00 67.67  ? 227 ILE A CG2 1 
ATOM   532   C CD1 . ILE A 1 228 ? 95.259  74.921  131.204 1.00 69.33  ? 227 ILE A CD1 1 
ATOM   533   N N   . GLY A 1 229 ? 97.332  74.213  136.931 1.00 118.22 ? 228 GLY A N   1 
ATOM   534   C CA  . GLY A 1 229 ? 97.864  73.485  138.071 1.00 187.37 ? 228 GLY A CA  1 
ATOM   535   C C   . GLY A 1 229 ? 96.913  72.390  138.549 1.00 211.25 ? 228 GLY A C   1 
ATOM   536   O O   . GLY A 1 229 ? 97.372  71.417  139.159 1.00 290.69 ? 228 GLY A O   1 
ATOM   537   N N   . ASP A 1 230 ? 95.595  72.559  138.299 1.00 150.00 ? 229 ASP A N   1 
ATOM   538   C CA  . ASP A 1 230 ? 94.657  71.475  138.571 1.00 173.92 ? 229 ASP A CA  1 
ATOM   539   C C   . ASP A 1 230 ? 93.596  71.459  137.488 1.00 146.11 ? 229 ASP A C   1 
ATOM   540   O O   . ASP A 1 230 ? 92.840  72.402  137.359 1.00 136.47 ? 229 ASP A O   1 
ATOM   541   C CB  . ASP A 1 230 ? 94.047  71.524  139.976 1.00 207.04 ? 229 ASP A CB  1 
ATOM   542   C CG  . ASP A 1 230 ? 93.268  70.272  140.386 1.00 262.71 ? 229 ASP A CG  1 
ATOM   543   O OD1 . ASP A 1 230 ? 92.809  69.522  139.485 1.00 303.78 ? 229 ASP A OD1 1 
ATOM   544   O OD2 . ASP A 1 230 ? 93.106  70.039  141.601 1.00 274.51 ? 229 ASP A OD2 1 
ATOM   545   N N   . LEU A 1 231 ? 93.578  70.339  136.748 1.00 118.67 ? 230 LEU A N   1 
ATOM   546   C CA  . LEU A 1 231 ? 92.654  70.118  135.657 1.00 117.88 ? 230 LEU A CA  1 
ATOM   547   C C   . LEU A 1 231 ? 91.200  70.202  136.084 1.00 140.44 ? 230 LEU A C   1 
ATOM   548   O O   . LEU A 1 231 ? 90.374  70.560  135.244 1.00 129.10 ? 230 LEU A O   1 
ATOM   549   C CB  . LEU A 1 231 ? 92.979  68.739  135.115 1.00 130.21 ? 230 LEU A CB  1 
ATOM   550   C CG  . LEU A 1 231 ? 94.238  68.744  134.271 1.00 172.45 ? 230 LEU A CG  1 
ATOM   551   C CD1 . LEU A 1 231 ? 94.813  67.337  134.080 1.00 244.20 ? 230 LEU A CD1 1 
ATOM   552   C CD2 . LEU A 1 231 ? 93.901  69.429  132.956 1.00 135.33 ? 230 LEU A CD2 1 
ATOM   553   N N   . GLN A 1 232 ? 90.926  69.866  137.356 1.00 158.82 ? 231 GLN A N   1 
ATOM   554   C CA  . GLN A 1 232 ? 89.573  69.865  137.897 1.00 179.76 ? 231 GLN A CA  1 
ATOM   555   C C   . GLN A 1 232 ? 89.128  71.301  138.093 1.00 143.74 ? 231 GLN A C   1 
ATOM   556   O O   . GLN A 1 232 ? 88.050  71.653  137.637 1.00 126.66 ? 231 GLN A O   1 
ATOM   557   C CB  . GLN A 1 232 ? 89.477  69.034  139.182 1.00 190.29 ? 231 GLN A CB  1 
ATOM   558   C CG  . GLN A 1 232 ? 89.683  67.545  138.905 1.00 258.85 ? 231 GLN A CG  1 
ATOM   559   C CD  . GLN A 1 232 ? 90.297  66.775  140.055 1.00 321.49 ? 231 GLN A CD  1 
ATOM   560   O OE1 . GLN A 1 232 ? 89.727  65.794  140.534 1.00 298.20 ? 231 GLN A OE1 1 
ATOM   561   N NE2 . GLN A 1 232 ? 91.469  67.202  140.511 1.00 384.38 ? 231 GLN A NE2 1 
ATOM   562   N N   . ALA A 1 233 ? 89.973  72.102  138.750 1.00 140.05 ? 232 ALA A N   1 
ATOM   563   C CA  . ALA A 1 233 ? 89.690  73.495  139.052 1.00 151.80 ? 232 ALA A CA  1 
ATOM   564   C C   . ALA A 1 233 ? 89.519  74.321  137.769 1.00 117.45 ? 232 ALA A C   1 
ATOM   565   O O   . ALA A 1 233 ? 88.771  75.296  137.776 1.00 85.98  ? 232 ALA A O   1 
ATOM   566   C CB  . ALA A 1 233 ? 90.762  74.074  139.967 1.00 176.96 ? 232 ALA A CB  1 
ATOM   567   N N   . PHE A 1 234 ? 90.194  73.941  136.680 1.00 90.35  ? 233 PHE A N   1 
ATOM   568   C CA  . PHE A 1 234 ? 90.071  74.667  135.431 1.00 94.62  ? 233 PHE A CA  1 
ATOM   569   C C   . PHE A 1 234 ? 88.754  74.393  134.737 1.00 113.79 ? 233 PHE A C   1 
ATOM   570   O O   . PHE A 1 234 ? 88.365  75.189  133.885 1.00 117.03 ? 233 PHE A O   1 
ATOM   571   C CB  . PHE A 1 234 ? 91.203  74.286  134.499 1.00 95.07  ? 233 PHE A CB  1 
ATOM   572   C CG  . PHE A 1 234 ? 91.372  75.119  133.260 1.00 81.15  ? 233 PHE A CG  1 
ATOM   573   C CD1 . PHE A 1 234 ? 91.362  76.492  133.315 1.00 119.13 ? 233 PHE A CD1 1 
ATOM   574   C CD2 . PHE A 1 234 ? 91.627  74.529  132.051 1.00 71.52  ? 233 PHE A CD2 1 
ATOM   575   C CE1 . PHE A 1 234 ? 91.553  77.257  132.181 1.00 110.43 ? 233 PHE A CE1 1 
ATOM   576   C CE2 . PHE A 1 234 ? 91.845  75.292  130.928 1.00 79.65  ? 233 PHE A CE2 1 
ATOM   577   C CZ  . PHE A 1 234 ? 91.807  76.647  131.002 1.00 84.67  ? 233 PHE A CZ  1 
ATOM   578   N N   . GLN A 1 235 ? 88.068  73.304  135.121 1.00 131.83 ? 234 GLN A N   1 
ATOM   579   C CA  . GLN A 1 235 ? 86.896  72.848  134.396 1.00 163.83 ? 234 GLN A CA  1 
ATOM   580   C C   . GLN A 1 235 ? 85.569  72.888  135.187 1.00 216.44 ? 234 GLN A C   1 
ATOM   581   O O   . GLN A 1 235 ? 84.511  73.106  134.590 1.00 152.83 ? 234 GLN A O   1 
ATOM   582   C CB  . GLN A 1 235 ? 87.262  71.434  133.964 1.00 167.87 ? 234 GLN A CB  1 
ATOM   583   C CG  . GLN A 1 235 ? 88.358  71.351  132.909 1.00 116.05 ? 234 GLN A CG  1 
ATOM   584   C CD  . GLN A 1 235 ? 87.793  71.753  131.557 1.00 192.14 ? 234 GLN A CD  1 
ATOM   585   O OE1 . GLN A 1 235 ? 86.789  72.451  131.365 1.00 205.26 ? 234 GLN A OE1 1 
ATOM   586   N NE2 . GLN A 1 235 ? 88.456  71.278  130.529 1.00 264.70 ? 234 GLN A NE2 1 
ATOM   587   N N   . GLY A 1 236 ? 85.595  72.670  136.513 1.00 237.69 ? 235 GLY A N   1 
ATOM   588   C CA  . GLY A 1 236 ? 84.432  72.192  137.252 1.00 236.05 ? 235 GLY A CA  1 
ATOM   589   C C   . GLY A 1 236 ? 84.374  70.664  137.207 1.00 297.97 ? 235 GLY A C   1 
ATOM   590   O O   . GLY A 1 236 ? 84.900  70.035  136.283 1.00 344.33 ? 235 GLY A O   1 
ATOM   591   N N   . HIS A 1 237 ? 83.736  70.064  138.219 1.00 363.26 ? 236 HIS A N   1 
ATOM   592   C CA  . HIS A 1 237 ? 83.884  68.634  138.474 1.00 408.28 ? 236 HIS A CA  1 
ATOM   593   C C   . HIS A 1 237 ? 83.117  67.810  137.438 1.00 361.91 ? 236 HIS A C   1 
ATOM   594   O O   . HIS A 1 237 ? 82.228  68.322  136.750 1.00 248.91 ? 236 HIS A O   1 
ATOM   595   C CB  . HIS A 1 237 ? 83.517  68.321  139.930 1.00 462.25 ? 236 HIS A CB  1 
ATOM   596   C CG  . HIS A 1 237 ? 84.432  69.029  140.879 1.00 521.88 ? 236 HIS A CG  1 
ATOM   597   N ND1 . HIS A 1 237 ? 85.754  68.678  141.054 1.00 521.45 ? 236 HIS A ND1 1 
ATOM   598   C CD2 . HIS A 1 237 ? 84.218  70.072  141.688 1.00 553.53 ? 236 HIS A CD2 1 
ATOM   599   C CE1 . HIS A 1 237 ? 86.309  69.485  141.945 1.00 526.20 ? 236 HIS A CE1 1 
ATOM   600   N NE2 . HIS A 1 237 ? 85.393  70.340  142.344 1.00 551.65 ? 236 HIS A NE2 1 
ATOM   601   N N   . GLY A 1 238 ? 83.492  66.524  137.341 1.00 394.09 ? 237 GLY A N   1 
ATOM   602   C CA  . GLY A 1 238 ? 82.947  65.605  136.352 1.00 408.82 ? 237 GLY A CA  1 
ATOM   603   C C   . GLY A 1 238 ? 83.666  65.730  135.011 1.00 385.84 ? 237 GLY A C   1 
ATOM   604   O O   . GLY A 1 238 ? 84.256  64.754  134.534 1.00 422.25 ? 237 GLY A O   1 
ATOM   605   N N   . ALA A 1 239 ? 83.600  66.942  134.427 1.00 319.10 ? 238 ALA A N   1 
ATOM   606   C CA  . ALA A 1 239 ? 84.394  67.330  133.268 1.00 275.08 ? 238 ALA A CA  1 
ATOM   607   C C   . ALA A 1 239 ? 85.888  67.469  133.600 1.00 261.12 ? 238 ALA A C   1 
ATOM   608   O O   . ALA A 1 239 ? 86.664  67.738  132.676 1.00 291.80 ? 238 ALA A O   1 
ATOM   609   C CB  . ALA A 1 239 ? 83.831  68.609  132.665 1.00 194.59 ? 238 ALA A CB  1 
ATOM   610   N N   . GLY A 1 240 ? 86.305  67.288  134.872 1.00 229.19 ? 239 GLY A N   1 
ATOM   611   C CA  . GLY A 1 240 ? 87.703  67.429  135.257 1.00 267.44 ? 239 GLY A CA  1 
ATOM   612   C C   . GLY A 1 240 ? 88.607  66.271  134.828 1.00 195.50 ? 239 GLY A C   1 
ATOM   613   O O   . GLY A 1 240 ? 89.080  65.543  135.687 1.00 208.08 ? 239 GLY A O   1 
ATOM   614   N N   . ASN A 1 241 ? 88.849  66.138  133.517 1.00 191.94 ? 240 ASN A N   1 
ATOM   615   C CA  . ASN A 1 241 ? 89.682  65.088  132.937 1.00 184.49 ? 240 ASN A CA  1 
ATOM   616   C C   . ASN A 1 241 ? 90.272  65.582  131.617 1.00 157.71 ? 240 ASN A C   1 
ATOM   617   O O   . ASN A 1 241 ? 89.787  66.573  131.062 1.00 156.01 ? 240 ASN A O   1 
ATOM   618   C CB  . ASN A 1 241 ? 88.916  63.771  132.719 1.00 232.66 ? 240 ASN A CB  1 
ATOM   619   C CG  . ASN A 1 241 ? 87.768  63.863  131.732 1.00 268.93 ? 240 ASN A CG  1 
ATOM   620   O OD1 . ASN A 1 241 ? 87.983  64.118  130.542 1.00 228.27 ? 240 ASN A OD1 1 
ATOM   621   N ND2 . ASN A 1 241 ? 86.552  63.661  132.220 1.00 300.00 ? 240 ASN A ND2 1 
ATOM   622   N N   . LEU A 1 242 ? 91.295  64.879  131.111 1.00 115.99 ? 241 LEU A N   1 
ATOM   623   C CA  . LEU A 1 242 ? 92.079  65.356  129.970 1.00 143.94 ? 241 LEU A CA  1 
ATOM   624   C C   . LEU A 1 242 ? 91.237  65.483  128.692 1.00 156.31 ? 241 LEU A C   1 
ATOM   625   O O   . LEU A 1 242 ? 91.499  66.346  127.859 1.00 160.81 ? 241 LEU A O   1 
ATOM   626   C CB  . LEU A 1 242 ? 93.234  64.388  129.740 1.00 116.52 ? 241 LEU A CB  1 
ATOM   627   C CG  . LEU A 1 242 ? 94.238  64.259  130.861 1.00 119.73 ? 241 LEU A CG  1 
ATOM   628   C CD1 . LEU A 1 242 ? 95.005  62.952  130.782 1.00 190.69 ? 241 LEU A CD1 1 
ATOM   629   C CD2 . LEU A 1 242 ? 95.219  65.379  130.772 1.00 157.29 ? 241 LEU A CD2 1 
ATOM   630   N N   . ALA A 1 243 ? 90.230  64.626  128.516 1.00 171.64 ? 242 ALA A N   1 
ATOM   631   C CA  . ALA A 1 243 ? 89.359  64.735  127.358 1.00 194.37 ? 242 ALA A CA  1 
ATOM   632   C C   . ALA A 1 243 ? 88.480  65.983  127.467 1.00 172.99 ? 242 ALA A C   1 
ATOM   633   O O   . ALA A 1 243 ? 88.026  66.520  126.445 1.00 200.02 ? 242 ALA A O   1 
ATOM   634   C CB  . ALA A 1 243 ? 88.525  63.480  127.229 1.00 288.76 ? 242 ALA A CB  1 
ATOM   635   N N   . GLY A 1 244 ? 88.227  66.438  128.701 1.00 145.29 ? 243 GLY A N   1 
ATOM   636   C CA  . GLY A 1 244 ? 87.578  67.718  128.921 1.00 206.30 ? 243 GLY A CA  1 
ATOM   637   C C   . GLY A 1 244 ? 88.456  68.867  128.443 1.00 170.12 ? 243 GLY A C   1 
ATOM   638   O O   . GLY A 1 244 ? 87.983  69.811  127.774 1.00 153.59 ? 243 GLY A O   1 
ATOM   639   N N   . LEU A 1 245 ? 89.737  68.764  128.819 1.00 121.12 ? 244 LEU A N   1 
ATOM   640   C CA  . LEU A 1 245 ? 90.701  69.794  128.480 1.00 181.81 ? 244 LEU A CA  1 
ATOM   641   C C   . LEU A 1 245 ? 90.848  69.890  126.947 1.00 134.45 ? 244 LEU A C   1 
ATOM   642   O O   . LEU A 1 245 ? 91.005  70.973  126.414 1.00 123.58 ? 244 LEU A O   1 
ATOM   643   C CB  . LEU A 1 245 ? 92.000  69.560  129.278 1.00 124.49 ? 244 LEU A CB  1 
ATOM   644   C CG  . LEU A 1 245 ? 93.162  70.432  128.850 1.00 137.39 ? 244 LEU A CG  1 
ATOM   645   C CD1 . LEU A 1 245 ? 92.881  71.910  129.024 1.00 165.99 ? 244 LEU A CD1 1 
ATOM   646   C CD2 . LEU A 1 245 ? 94.365  70.072  129.627 1.00 122.63 ? 244 LEU A CD2 1 
ATOM   647   N N   . LYS A 1 246 ? 90.780  68.775  126.241 1.00 119.81 ? 245 LYS A N   1 
ATOM   648   C CA  . LYS A 1 246 ? 90.853  68.786  124.788 1.00 162.39 ? 245 LYS A CA  1 
ATOM   649   C C   . LYS A 1 246 ? 89.802  69.726  124.202 1.00 153.30 ? 245 LYS A C   1 
ATOM   650   O O   . LYS A 1 246 ? 89.975  70.206  123.082 1.00 173.06 ? 245 LYS A O   1 
ATOM   651   C CB  . LYS A 1 246 ? 90.678  67.346  124.277 1.00 218.26 ? 245 LYS A CB  1 
ATOM   652   C CG  . LYS A 1 246 ? 90.801  67.088  122.774 1.00 206.03 ? 245 LYS A CG  1 
ATOM   653   C CD  . LYS A 1 246 ? 90.904  65.586  122.475 1.00 262.74 ? 245 LYS A CD  1 
ATOM   654   C CE  . LYS A 1 246 ? 89.598  64.897  122.815 1.00 297.64 ? 245 LYS A CE  1 
ATOM   655   N NZ  . LYS A 1 246 ? 89.406  63.626  122.081 1.00 351.71 ? 245 LYS A NZ  1 
ATOM   656   N N   . GLY A 1 247 ? 88.702  69.958  124.939 1.00 130.11 ? 246 GLY A N   1 
ATOM   657   C CA  . GLY A 1 247 ? 87.645  70.840  124.472 1.00 190.93 ? 246 GLY A CA  1 
ATOM   658   C C   . GLY A 1 247 ? 88.010  72.320  124.511 1.00 204.32 ? 246 GLY A C   1 
ATOM   659   O O   . GLY A 1 247 ? 87.506  73.117  123.706 1.00 246.21 ? 246 GLY A O   1 
ATOM   660   N N   . ARG A 1 248 ? 88.877  72.679  125.465 1.00 177.64 ? 247 ARG A N   1 
ATOM   661   C CA  . ARG A 1 248 ? 89.076  74.071  125.831 1.00 141.30 ? 247 ARG A CA  1 
ATOM   662   C C   . ARG A 1 248 ? 90.166  74.771  125.073 1.00 122.72 ? 247 ARG A C   1 
ATOM   663   O O   . ARG A 1 248 ? 90.168  75.982  125.111 1.00 120.31 ? 247 ARG A O   1 
ATOM   664   C CB  . ARG A 1 248 ? 89.538  74.154  127.254 1.00 130.91 ? 247 ARG A CB  1 
ATOM   665   C CG  . ARG A 1 248 ? 88.370  73.799  128.141 1.00 160.74 ? 247 ARG A CG  1 
ATOM   666   C CD  . ARG A 1 248 ? 87.331  74.897  128.258 1.00 191.54 ? 247 ARG A CD  1 
ATOM   667   N NE  . ARG A 1 248 ? 86.578  74.544  129.454 1.00 219.87 ? 247 ARG A NE  1 
ATOM   668   C CZ  . ARG A 1 248 ? 85.436  75.100  129.803 1.00 210.54 ? 247 ARG A CZ  1 
ATOM   669   N NH1 . ARG A 1 248 ? 84.788  74.583  130.843 1.00 167.00 ? 247 ARG A NH1 1 
ATOM   670   N NH2 . ARG A 1 248 ? 84.979  76.147  129.110 1.00 143.27 ? 247 ARG A NH2 1 
ATOM   671   N N   . LEU A 1 249 ? 91.021  74.007  124.399 1.00 117.45 ? 248 LEU A N   1 
ATOM   672   C CA  . LEU A 1 249 ? 92.078  74.539  123.565 1.00 121.21 ? 248 LEU A CA  1 
ATOM   673   C C   . LEU A 1 249 ? 91.642  75.692  122.633 1.00 118.51 ? 248 LEU A C   1 
ATOM   674   O O   . LEU A 1 249 ? 92.517  76.445  122.204 1.00 110.33 ? 248 LEU A O   1 
ATOM   675   C CB  . LEU A 1 249 ? 92.663  73.402  122.728 1.00 105.94 ? 248 LEU A CB  1 
ATOM   676   C CG  . LEU A 1 249 ? 93.283  72.188  123.422 1.00 140.15 ? 248 LEU A CG  1 
ATOM   677   C CD1 . LEU A 1 249 ? 94.036  71.406  122.380 1.00 215.59 ? 248 LEU A CD1 1 
ATOM   678   C CD2 . LEU A 1 249 ? 94.232  72.496  124.543 1.00 145.84 ? 248 LEU A CD2 1 
ATOM   679   N N   . ASP A 1 250 ? 90.346  75.864  122.290 1.00 127.56 ? 249 ASP A N   1 
ATOM   680   C CA  . ASP A 1 250 ? 89.963  76.951  121.401 1.00 155.69 ? 249 ASP A CA  1 
ATOM   681   C C   . ASP A 1 250 ? 90.061  78.293  122.132 1.00 146.11 ? 249 ASP A C   1 
ATOM   682   O O   . ASP A 1 250 ? 90.297  79.359  121.539 1.00 150.97 ? 249 ASP A O   1 
ATOM   683   C CB  . ASP A 1 250 ? 88.591  76.684  120.770 1.00 198.21 ? 249 ASP A CB  1 
ATOM   684   C CG  . ASP A 1 250 ? 88.402  77.442  119.461 1.00 367.00 ? 249 ASP A CG  1 
ATOM   685   O OD1 . ASP A 1 250 ? 89.376  77.523  118.664 1.00 423.28 ? 249 ASP A OD1 1 
ATOM   686   O OD2 . ASP A 1 250 ? 87.278  77.951  119.238 1.00 472.12 ? 249 ASP A OD2 1 
ATOM   687   N N   . TYR A 1 251 ? 89.850  78.233  123.442 1.00 140.72 ? 250 TYR A N   1 
ATOM   688   C CA  . TYR A 1 251 ? 90.069  79.380  124.296 1.00 142.75 ? 250 TYR A CA  1 
ATOM   689   C C   . TYR A 1 251 ? 91.535  79.703  124.353 1.00 94.30  ? 250 TYR A C   1 
ATOM   690   O O   . TYR A 1 251 ? 91.905  80.843  124.117 1.00 98.54  ? 250 TYR A O   1 
ATOM   691   C CB  . TYR A 1 251 ? 89.607  79.067  125.702 1.00 132.81 ? 250 TYR A CB  1 
ATOM   692   C CG  . TYR A 1 251 ? 89.886  80.162  126.708 1.00 115.34 ? 250 TYR A CG  1 
ATOM   693   C CD1 . TYR A 1 251 ? 89.603  81.514  126.510 1.00 150.94 ? 250 TYR A CD1 1 
ATOM   694   C CD2 . TYR A 1 251 ? 90.436  79.792  127.905 1.00 98.92  ? 250 TYR A CD2 1 
ATOM   695   C CE1 . TYR A 1 251 ? 89.875  82.437  127.509 1.00 145.21 ? 250 TYR A CE1 1 
ATOM   696   C CE2 . TYR A 1 251 ? 90.677  80.693  128.915 1.00 88.76  ? 250 TYR A CE2 1 
ATOM   697   C CZ  . TYR A 1 251 ? 90.415  82.017  128.716 1.00 112.05 ? 250 TYR A CZ  1 
ATOM   698   O OH  . TYR A 1 251 ? 90.718  82.807  129.774 1.00 144.28 ? 250 TYR A OH  1 
ATOM   699   N N   . LEU A 1 252 ? 92.320  78.690  124.664 1.00 66.19  ? 251 LEU A N   1 
ATOM   700   C CA  . LEU A 1 252 ? 93.746  78.892  124.757 1.00 83.64  ? 251 LEU A CA  1 
ATOM   701   C C   . LEU A 1 252 ? 94.285  79.440  123.408 1.00 84.51  ? 251 LEU A C   1 
ATOM   702   O O   . LEU A 1 252 ? 95.119  80.358  123.390 1.00 85.95  ? 251 LEU A O   1 
ATOM   703   C CB  . LEU A 1 252 ? 94.410  77.589  125.250 1.00 74.12  ? 251 LEU A CB  1 
ATOM   704   C CG  . LEU A 1 252 ? 93.934  76.975  126.584 1.00 71.72  ? 251 LEU A CG  1 
ATOM   705   C CD1 . LEU A 1 252 ? 94.925  75.959  127.063 1.00 80.88  ? 251 LEU A CD1 1 
ATOM   706   C CD2 . LEU A 1 252 ? 93.776  77.994  127.670 1.00 88.89  ? 251 LEU A CD2 1 
ATOM   707   N N   . SER A 1 253 ? 93.822  78.913  122.284 1.00 74.39  ? 252 SER A N   1 
ATOM   708   C CA  . SER A 1 253 ? 94.226  79.451  121.009 1.00 103.50 ? 252 SER A CA  1 
ATOM   709   C C   . SER A 1 253 ? 93.809  80.943  120.897 1.00 119.45 ? 252 SER A C   1 
ATOM   710   O O   . SER A 1 253 ? 94.524  81.732  120.249 1.00 161.68 ? 252 SER A O   1 
ATOM   711   C CB  . SER A 1 253 ? 93.696  78.539  119.918 1.00 135.52 ? 252 SER A CB  1 
ATOM   712   O OG  . SER A 1 253 ? 94.017  79.023  118.627 1.00 187.20 ? 252 SER A OG  1 
ATOM   713   N N   . SER A 1 254 ? 92.680  81.357  121.535 1.00 88.03  ? 253 SER A N   1 
ATOM   714   C CA  . SER A 1 254 ? 92.249  82.768  121.611 1.00 158.69 ? 253 SER A CA  1 
ATOM   715   C C   . SER A 1 254 ? 93.191  83.662  122.410 1.00 142.13 ? 253 SER A C   1 
ATOM   716   O O   . SER A 1 254 ? 93.438  84.809  122.054 1.00 156.87 ? 253 SER A O   1 
ATOM   717   C CB  . SER A 1 254 ? 90.849  82.906  122.145 1.00 173.85 ? 253 SER A CB  1 
ATOM   718   O OG  . SER A 1 254 ? 89.952  82.204  121.284 1.00 298.09 ? 253 SER A OG  1 
ATOM   719   N N   . LEU A 1 255 ? 93.746  83.099  123.478 1.00 128.33 ? 254 LEU A N   1 
ATOM   720   C CA  . LEU A 1 255 ? 94.829  83.730  124.228 1.00 79.90  ? 254 LEU A CA  1 
ATOM   721   C C   . LEU A 1 255 ? 96.163  83.787  123.509 1.00 66.66  ? 254 LEU A C   1 
ATOM   722   O O   . LEU A 1 255 ? 97.061  84.459  123.974 1.00 108.13 ? 254 LEU A O   1 
ATOM   723   C CB  . LEU A 1 255 ? 95.007  82.896  125.490 1.00 65.55  ? 254 LEU A CB  1 
ATOM   724   C CG  . LEU A 1 255 ? 93.786  82.897  126.427 1.00 72.59  ? 254 LEU A CG  1 
ATOM   725   C CD1 . LEU A 1 255 ? 94.058  82.178  127.702 1.00 81.02  ? 254 LEU A CD1 1 
ATOM   726   C CD2 . LEU A 1 255 ? 93.381  84.298  126.756 1.00 69.12  ? 254 LEU A CD2 1 
ATOM   727   N N   . LYS A 1 256 ? 96.310  83.084  122.404 1.00 104.04 ? 255 LYS A N   1 
ATOM   728   C CA  . LYS A 1 256 ? 97.532  83.076  121.603 1.00 123.83 ? 255 LYS A CA  1 
ATOM   729   C C   . LYS A 1 256 ? 98.714  82.518  122.417 1.00 82.07  ? 255 LYS A C   1 
ATOM   730   O O   . LYS A 1 256 ? 99.887  82.839  122.116 1.00 69.59  ? 255 LYS A O   1 
ATOM   731   C CB  . LYS A 1 256 ? 97.729  84.446  120.941 1.00 123.29 ? 255 LYS A CB  1 
ATOM   732   C CG  . LYS A 1 256 ? 96.548  84.921  120.097 1.00 139.32 ? 255 LYS A CG  1 
ATOM   733   C CD  . LYS A 1 256 ? 96.885  86.162  119.274 1.00 210.50 ? 255 LYS A CD  1 
ATOM   734   C CE  . LYS A 1 256 ? 95.715  86.709  118.485 1.00 308.02 ? 255 LYS A CE  1 
ATOM   735   N NZ  . LYS A 1 256 ? 94.507  86.930  119.325 1.00 310.25 ? 255 LYS A NZ  1 
ATOM   736   N N   . VAL A 1 257 ? 98.355  81.642  123.394 1.00 51.50  ? 256 VAL A N   1 
ATOM   737   C CA  . VAL A 1 257 ? 99.374  81.031  124.214 1.00 61.73  ? 256 VAL A CA  1 
ATOM   738   C C   . VAL A 1 257 ? 100.141 79.935  123.484 1.00 57.37  ? 256 VAL A C   1 
ATOM   739   O O   . VAL A 1 257 ? 99.578  78.936  123.110 1.00 88.71  ? 256 VAL A O   1 
ATOM   740   C CB  . VAL A 1 257 ? 98.895  80.534  125.573 1.00 63.26  ? 256 VAL A CB  1 
ATOM   741   C CG1 . VAL A 1 257 ? 98.596  81.761  126.404 1.00 98.23  ? 256 VAL A CG1 1 
ATOM   742   C CG2 . VAL A 1 257 ? 97.767  79.579  125.522 1.00 57.53  ? 256 VAL A CG2 1 
ATOM   743   N N   . LYS A 1 258 ? 101.466 80.143  123.329 1.00 63.41  ? 257 LYS A N   1 
ATOM   744   C CA  . LYS A 1 258 ? 102.369 79.289  122.585 1.00 79.58  ? 257 LYS A CA  1 
ATOM   745   C C   . LYS A 1 258 ? 102.776 78.063  123.394 1.00 56.99  ? 257 LYS A C   1 
ATOM   746   O O   . LYS A 1 258 ? 103.795 77.477  123.062 1.00 103.82 ? 257 LYS A O   1 
ATOM   747   C CB  . LYS A 1 258 ? 103.563 80.114  122.067 1.00 89.87  ? 257 LYS A CB  1 
ATOM   748   C CG  . LYS A 1 258 ? 103.187 81.252  121.104 1.00 114.74 ? 257 LYS A CG  1 
ATOM   749   C CD  . LYS A 1 258 ? 102.552 80.832  119.800 1.00 180.41 ? 257 LYS A CD  1 
ATOM   750   C CE  . LYS A 1 258 ? 102.364 81.982  118.841 1.00 253.91 ? 257 LYS A CE  1 
ATOM   751   N NZ  . LYS A 1 258 ? 101.938 81.521  117.500 1.00 325.04 ? 257 LYS A NZ  1 
ATOM   752   N N   . GLY A 1 259 ? 101.978 77.663  124.374 1.00 48.61  ? 258 GLY A N   1 
ATOM   753   C CA  . GLY A 1 259 ? 102.373 76.722  125.415 1.00 57.50  ? 258 GLY A CA  1 
ATOM   754   C C   . GLY A 1 259 ? 101.247 76.430  126.424 1.00 54.17  ? 258 GLY A C   1 
ATOM   755   O O   . GLY A 1 259 ? 100.202 77.087  126.396 1.00 67.80  ? 258 GLY A O   1 
ATOM   756   N N   . LEU A 1 260 ? 101.504 75.436  127.255 1.00 44.79  ? 259 LEU A N   1 
ATOM   757   C CA  . LEU A 1 260 ? 100.644 74.861  128.262 1.00 50.57  ? 259 LEU A CA  1 
ATOM   758   C C   . LEU A 1 260 ? 101.511 74.051  129.218 1.00 64.93  ? 259 LEU A C   1 
ATOM   759   O O   . LEU A 1 260 ? 102.576 73.610  128.819 1.00 110.07 ? 259 LEU A O   1 
ATOM   760   C CB  . LEU A 1 260 ? 99.693  73.863  127.641 1.00 51.73  ? 259 LEU A CB  1 
ATOM   761   C CG  . LEU A 1 260 ? 98.233  74.132  127.601 1.00 66.83  ? 259 LEU A CG  1 
ATOM   762   C CD1 . LEU A 1 260 ? 97.499  72.922  127.107 1.00 120.98 ? 259 LEU A CD1 1 
ATOM   763   C CD2 . LEU A 1 260 ? 97.783  74.260  129.002 1.00 100.30 ? 259 LEU A CD2 1 
ATOM   764   N N   . VAL A 1 261 ? 101.067 73.807  130.431 1.00 60.37  ? 260 VAL A N   1 
ATOM   765   C CA  . VAL A 1 261 ? 101.872 73.128  131.430 1.00 62.05  ? 260 VAL A CA  1 
ATOM   766   C C   . VAL A 1 261 ? 100.887 72.399  132.338 1.00 60.33  ? 260 VAL A C   1 
ATOM   767   O O   . VAL A 1 261 ? 100.257 73.058  133.205 1.00 96.25  ? 260 VAL A O   1 
ATOM   768   C CB  . VAL A 1 261 ? 102.731 74.134  132.246 1.00 69.54  ? 260 VAL A CB  1 
ATOM   769   C CG1 . VAL A 1 261 ? 103.577 73.403  133.267 1.00 83.34  ? 260 VAL A CG1 1 
ATOM   770   C CG2 . VAL A 1 261 ? 103.638 75.030  131.446 1.00 56.74  ? 260 VAL A CG2 1 
ATOM   771   N N   . LEU A 1 262 ? 100.710 71.086  132.170 1.00 59.64  ? 261 LEU A N   1 
ATOM   772   C CA  . LEU A 1 262 ? 99.635  70.416  132.934 1.00 73.68  ? 261 LEU A CA  1 
ATOM   773   C C   . LEU A 1 262 ? 100.265 69.920  134.191 1.00 86.51  ? 261 LEU A C   1 
ATOM   774   O O   . LEU A 1 262 ? 101.156 69.046  134.109 1.00 50.91  ? 261 LEU A O   1 
ATOM   775   C CB  . LEU A 1 262 ? 98.906  69.171  132.433 1.00 58.50  ? 261 LEU A CB  1 
ATOM   776   C CG  . LEU A 1 262 ? 97.916  69.471  131.333 1.00 104.84 ? 261 LEU A CG  1 
ATOM   777   C CD1 . LEU A 1 262 ? 98.237  70.763  130.358 1.00 63.14  ? 261 LEU A CD1 1 
ATOM   778   C CD2 . LEU A 1 262 ? 97.793  68.102  130.625 1.00 136.07 ? 261 LEU A CD2 1 
ATOM   779   N N   . GLY A 1 263 ? 99.744  70.574  135.270 1.00 157.71 ? 262 GLY A N   1 
ATOM   780   C CA  . GLY A 1 263 ? 100.056 70.285  136.648 1.00 156.05 ? 262 GLY A CA  1 
ATOM   781   C C   . GLY A 1 263 ? 99.978  68.786  136.824 1.00 102.28 ? 262 GLY A C   1 
ATOM   782   O O   . GLY A 1 263 ? 99.257  68.110  136.125 1.00 55.29  ? 262 GLY A O   1 
ATOM   783   N N   . PRO A 1 264 ? 100.773 68.226  137.727 1.00 98.57  ? 263 PRO A N   1 
ATOM   784   C CA  . PRO A 1 264 ? 101.114 66.824  137.641 1.00 116.68 ? 263 PRO A CA  1 
ATOM   785   C C   . PRO A 1 264 ? 99.938  65.895  137.552 1.00 122.00 ? 263 PRO A C   1 
ATOM   786   O O   . PRO A 1 264 ? 98.990  66.070  138.306 1.00 107.71 ? 263 PRO A O   1 
ATOM   787   C CB  . PRO A 1 264 ? 101.834 66.600  138.934 1.00 127.73 ? 263 PRO A CB  1 
ATOM   788   C CG  . PRO A 1 264 ? 102.509 67.901  139.173 1.00 129.02 ? 263 PRO A CG  1 
ATOM   789   C CD  . PRO A 1 264 ? 101.437 68.905  138.827 1.00 116.84 ? 263 PRO A CD  1 
ATOM   790   N N   . ILE A 1 265 ? 100.067 64.946  136.612 1.00 118.15 ? 264 ILE A N   1 
ATOM   791   C CA  . ILE A 1 265 ? 99.030  63.987  136.334 1.00 97.35  ? 264 ILE A CA  1 
ATOM   792   C C   . ILE A 1 265 ? 99.520  62.616  136.665 1.00 100.76 ? 264 ILE A C   1 
ATOM   793   O O   . ILE A 1 265 ? 98.707  61.703  136.521 1.00 148.57 ? 264 ILE A O   1 
ATOM   794   C CB  . ILE A 1 265 ? 98.531  64.036  134.882 1.00 88.34  ? 264 ILE A CB  1 
ATOM   795   C CG1 . ILE A 1 265 ? 99.585  63.678  133.843 1.00 123.80 ? 264 ILE A CG1 1 
ATOM   796   C CG2 . ILE A 1 265 ? 97.913  65.379  134.552 1.00 95.57  ? 264 ILE A CG2 1 
ATOM   797   C CD1 . ILE A 1 265 ? 98.993  63.501  132.485 1.00 152.42 ? 264 ILE A CD1 1 
ATOM   798   N N   . HIS A 1 266 ? 100.759 62.471  137.123 1.00 78.11  ? 265 HIS A N   1 
ATOM   799   C CA  . HIS A 1 266 ? 101.176 61.119  137.397 1.00 114.92 ? 265 HIS A CA  1 
ATOM   800   C C   . HIS A 1 266 ? 100.550 60.562  138.683 1.00 118.43 ? 265 HIS A C   1 
ATOM   801   O O   . HIS A 1 266 ? 100.051 61.321  139.501 1.00 113.23 ? 265 HIS A O   1 
ATOM   802   C CB  . HIS A 1 266 ? 102.681 61.146  137.389 1.00 172.51 ? 265 HIS A CB  1 
ATOM   803   C CG  . HIS A 1 266 ? 103.261 61.989  138.451 1.00 132.86 ? 265 HIS A CG  1 
ATOM   804   N ND1 . HIS A 1 266 ? 103.728 63.253  138.193 1.00 127.59 ? 265 HIS A ND1 1 
ATOM   805   C CD2 . HIS A 1 266 ? 103.464 61.729  139.724 1.00 100.00 ? 265 HIS A CD2 1 
ATOM   806   C CE1 . HIS A 1 266 ? 104.220 63.737  139.309 1.00 158.42 ? 265 HIS A CE1 1 
ATOM   807   N NE2 . HIS A 1 266 ? 104.068 62.823  140.254 1.00 111.05 ? 265 HIS A NE2 1 
ATOM   808   N N   . LYS A 1 267 ? 100.572 59.220  138.840 1.00 121.19 ? 266 LYS A N   1 
ATOM   809   C CA  . LYS A 1 267 ? 99.942  58.546  139.972 1.00 153.28 ? 266 LYS A CA  1 
ATOM   810   C C   . LYS A 1 267 ? 100.796 58.701  141.228 1.00 120.34 ? 266 LYS A C   1 
ATOM   811   O O   . LYS A 1 267 ? 101.679 57.908  141.505 1.00 149.49 ? 266 LYS A O   1 
ATOM   812   C CB  . LYS A 1 267 ? 99.680  57.069  139.643 1.00 228.62 ? 266 LYS A CB  1 
ATOM   813   C CG  . LYS A 1 267 ? 98.897  56.297  140.708 1.00 223.15 ? 266 LYS A CG  1 
ATOM   814   C CD  . LYS A 1 267 ? 98.629  54.838  140.330 1.00 256.70 ? 266 LYS A CD  1 
ATOM   815   C CE  . LYS A 1 267 ? 98.446  53.894  141.507 1.00 339.52 ? 266 LYS A CE  1 
ATOM   816   N NZ  . LYS A 1 267 ? 99.714  53.619  142.241 1.00 405.91 ? 266 LYS A NZ  1 
ATOM   817   N N   . ASN A 1 268 ? 100.492 59.736  141.995 1.00 160.25 ? 267 ASN A N   1 
ATOM   818   C CA  . ASN A 1 268 ? 101.123 60.023  143.266 1.00 160.40 ? 267 ASN A CA  1 
ATOM   819   C C   . ASN A 1 268 ? 100.155 59.648  144.378 1.00 165.83 ? 267 ASN A C   1 
ATOM   820   O O   . ASN A 1 268 ? 98.991  60.055  144.350 1.00 164.40 ? 267 ASN A O   1 
ATOM   821   C CB  . ASN A 1 268 ? 101.507 61.507  143.324 1.00 233.55 ? 267 ASN A CB  1 
ATOM   822   C CG  . ASN A 1 268 ? 101.917 62.010  144.689 1.00 177.76 ? 267 ASN A CG  1 
ATOM   823   O OD1 . ASN A 1 268 ? 101.480 63.077  145.092 1.00 131.73 ? 267 ASN A OD1 1 
ATOM   824   N ND2 . ASN A 1 268 ? 102.747 61.275  145.397 1.00 156.21 ? 267 ASN A ND2 1 
ATOM   825   N N   . GLN A 1 269 ? 100.661 58.877  145.349 1.00 182.49 ? 268 GLN A N   1 
ATOM   826   C CA  . GLN A 1 269 ? 99.981  58.645  146.615 1.00 217.43 ? 268 GLN A CA  1 
ATOM   827   C C   . GLN A 1 269 ? 100.690 59.481  147.683 1.00 198.38 ? 268 GLN A C   1 
ATOM   828   O O   . GLN A 1 269 ? 101.910 59.435  147.798 1.00 169.67 ? 268 GLN A O   1 
ATOM   829   C CB  . GLN A 1 269 ? 99.931  57.135  146.904 1.00 247.36 ? 268 GLN A CB  1 
ATOM   830   C CG  . GLN A 1 269 ? 99.600  56.732  148.344 1.00 281.10 ? 268 GLN A CG  1 
ATOM   831   C CD  . GLN A 1 269 ? 98.295  57.243  148.915 1.00 330.01 ? 268 GLN A CD  1 
ATOM   832   O OE1 . GLN A 1 269 ? 97.616  58.101  148.352 1.00 352.07 ? 268 GLN A OE1 1 
ATOM   833   N NE2 . GLN A 1 269 ? 97.931  56.717  150.073 1.00 354.55 ? 268 GLN A NE2 1 
ATOM   834   N N   . LYS A 1 270 ? 99.914  60.237  148.470 1.00 209.28 ? 269 LYS A N   1 
ATOM   835   C CA  . LYS A 1 270 ? 100.463 61.298  149.311 1.00 198.95 ? 269 LYS A CA  1 
ATOM   836   C C   . LYS A 1 270 ? 101.560 60.749  150.259 1.00 156.22 ? 269 LYS A C   1 
ATOM   837   O O   . LYS A 1 270 ? 101.344 59.821  151.035 1.00 157.87 ? 269 LYS A O   1 
ATOM   838   C CB  . LYS A 1 270 ? 99.287  62.000  150.004 1.00 162.06 ? 269 LYS A CB  1 
ATOM   839   C CG  . LYS A 1 270 ? 99.681  63.032  151.043 1.00 205.70 ? 269 LYS A CG  1 
ATOM   840   C CD  . LYS A 1 270 ? 98.494  63.649  151.744 1.00 252.51 ? 269 LYS A CD  1 
ATOM   841   C CE  . LYS A 1 270 ? 98.890  64.764  152.695 1.00 318.93 ? 269 LYS A CE  1 
ATOM   842   N NZ  . LYS A 1 270 ? 99.817  64.310  153.762 1.00 318.25 ? 269 LYS A NZ  1 
ATOM   843   N N   . ASP A 1 271 ? 102.759 61.335  150.158 1.00 144.10 ? 270 ASP A N   1 
ATOM   844   C CA  . ASP A 1 271 ? 103.937 61.065  150.978 1.00 163.86 ? 270 ASP A CA  1 
ATOM   845   C C   . ASP A 1 271 ? 104.453 59.621  150.896 1.00 176.42 ? 270 ASP A C   1 
ATOM   846   O O   . ASP A 1 271 ? 105.377 59.293  151.641 1.00 184.16 ? 270 ASP A O   1 
ATOM   847   C CB  . ASP A 1 271 ? 103.673 61.554  152.411 1.00 190.54 ? 270 ASP A CB  1 
ATOM   848   C CG  . ASP A 1 271 ? 103.326 63.035  152.500 1.00 265.31 ? 270 ASP A CG  1 
ATOM   849   O OD1 . ASP A 1 271 ? 104.022 63.824  151.829 1.00 313.49 ? 270 ASP A OD1 1 
ATOM   850   O OD2 . ASP A 1 271 ? 102.375 63.394  153.242 1.00 300.17 ? 270 ASP A OD2 1 
ATOM   851   N N   . ASP A 1 272 ? 103.910 58.779  149.997 1.00 182.80 ? 271 ASP A N   1 
ATOM   852   C CA  . ASP A 1 272 ? 104.361 57.406  149.821 1.00 236.82 ? 271 ASP A CA  1 
ATOM   853   C C   . ASP A 1 272 ? 105.288 57.332  148.596 1.00 201.36 ? 271 ASP A C   1 
ATOM   854   O O   . ASP A 1 272 ? 104.843 57.400  147.443 1.00 268.04 ? 271 ASP A O   1 
ATOM   855   C CB  . ASP A 1 272 ? 103.165 56.452  149.702 1.00 305.82 ? 271 ASP A CB  1 
ATOM   856   C CG  . ASP A 1 272 ? 103.512 54.968  149.733 1.00 365.64 ? 271 ASP A CG  1 
ATOM   857   O OD1 . ASP A 1 272 ? 104.577 54.588  149.188 1.00 401.42 ? 271 ASP A OD1 1 
ATOM   858   O OD2 . ASP A 1 272 ? 102.710 54.194  150.293 1.00 381.44 ? 271 ASP A OD2 1 
ATOM   859   N N   . VAL A 1 273 ? 106.585 57.158  148.858 1.00 147.91 ? 272 VAL A N   1 
ATOM   860   C CA  . VAL A 1 273 ? 107.622 57.111  147.838 1.00 148.23 ? 272 VAL A CA  1 
ATOM   861   C C   . VAL A 1 273 ? 107.420 55.910  146.914 1.00 163.13 ? 272 VAL A C   1 
ATOM   862   O O   . VAL A 1 273 ? 107.736 56.009  145.735 1.00 179.73 ? 272 VAL A O   1 
ATOM   863   C CB  . VAL A 1 273 ? 109.018 57.018  148.493 1.00 199.65 ? 272 VAL A CB  1 
ATOM   864   C CG1 . VAL A 1 273 ? 110.174 56.996  147.473 1.00 183.60 ? 272 VAL A CG1 1 
ATOM   865   C CG2 . VAL A 1 273 ? 109.201 58.105  149.561 1.00 219.90 ? 272 VAL A CG2 1 
ATOM   866   N N   . ALA A 1 274 ? 106.924 54.780  147.456 1.00 191.30 ? 273 ALA A N   1 
ATOM   867   C CA  . ALA A 1 274 ? 106.909 53.501  146.765 1.00 246.30 ? 273 ALA A CA  1 
ATOM   868   C C   . ALA A 1 274 ? 105.642 53.332  145.916 1.00 228.32 ? 273 ALA A C   1 
ATOM   869   O O   . ALA A 1 274 ? 105.703 52.788  144.809 1.00 173.21 ? 273 ALA A O   1 
ATOM   870   C CB  . ALA A 1 274 ? 107.052 52.403  147.792 1.00 295.49 ? 273 ALA A CB  1 
ATOM   871   N N   . GLN A 1 275 ? 104.492 53.788  146.434 1.00 251.88 ? 274 GLN A N   1 
ATOM   872   C CA  . GLN A 1 275 ? 103.227 53.730  145.709 1.00 280.40 ? 274 GLN A CA  1 
ATOM   873   C C   . GLN A 1 275 ? 103.117 54.824  144.645 1.00 247.41 ? 274 GLN A C   1 
ATOM   874   O O   . GLN A 1 275 ? 102.256 54.721  143.770 1.00 271.22 ? 274 GLN A O   1 
ATOM   875   C CB  . GLN A 1 275 ? 102.044 53.838  146.679 1.00 318.64 ? 274 GLN A CB  1 
ATOM   876   C CG  . GLN A 1 275 ? 101.853 52.608  147.563 1.00 365.63 ? 274 GLN A CG  1 
ATOM   877   C CD  . GLN A 1 275 ? 101.373 51.365  146.833 1.00 359.49 ? 274 GLN A CD  1 
ATOM   878   O OE1 . GLN A 1 275 ? 101.140 51.353  145.623 1.00 305.81 ? 274 GLN A OE1 1 
ATOM   879   N NE2 . GLN A 1 275 ? 101.224 50.282  147.577 1.00 385.30 ? 274 GLN A NE2 1 
ATOM   880   N N   . THR A 1 276 ? 103.969 55.859  144.714 1.00 206.33 ? 275 THR A N   1 
ATOM   881   C CA  . THR A 1 276 ? 104.046 56.889  143.687 1.00 189.26 ? 275 THR A CA  1 
ATOM   882   C C   . THR A 1 276 ? 104.841 56.413  142.468 1.00 191.15 ? 275 THR A C   1 
ATOM   883   O O   . THR A 1 276 ? 105.935 55.873  142.599 1.00 152.07 ? 275 THR A O   1 
ATOM   884   C CB  . THR A 1 276 ? 104.693 58.171  144.214 1.00 200.90 ? 275 THR A CB  1 
ATOM   885   O OG1 . THR A 1 276 ? 103.826 58.681  145.220 1.00 241.53 ? 275 THR A OG1 1 
ATOM   886   C CG2 . THR A 1 276 ? 104.906 59.240  143.165 1.00 173.76 ? 275 THR A CG2 1 
ATOM   887   N N   . ASP A 1 277 ? 104.275 56.674  141.275 1.00 227.83 ? 276 ASP A N   1 
ATOM   888   C CA  . ASP A 1 277 ? 104.909 56.454  139.979 1.00 177.20 ? 276 ASP A CA  1 
ATOM   889   C C   . ASP A 1 277 ? 104.828 57.724  139.141 1.00 150.30 ? 276 ASP A C   1 
ATOM   890   O O   . ASP A 1 277 ? 103.765 58.390  139.192 1.00 129.77 ? 276 ASP A O   1 
ATOM   891   C CB  . ASP A 1 277 ? 104.213 55.321  139.244 1.00 179.84 ? 276 ASP A CB  1 
ATOM   892   C CG  . ASP A 1 277 ? 104.838 55.037  137.894 1.00 243.61 ? 276 ASP A CG  1 
ATOM   893   O OD1 . ASP A 1 277 ? 106.021 55.462  137.664 1.00 217.89 ? 276 ASP A OD1 1 
ATOM   894   O OD2 . ASP A 1 277 ? 104.138 54.416  137.058 1.00 307.36 ? 276 ASP A OD2 1 
ATOM   895   N N   . LEU A 1 278 ? 105.931 58.052  138.416 1.00 127.79 ? 277 LEU A N   1 
ATOM   896   C CA  . LEU A 1 278 ? 105.913 59.275  137.600 1.00 164.19 ? 277 LEU A CA  1 
ATOM   897   C C   . LEU A 1 278 ? 105.536 58.966  136.162 1.00 173.96 ? 277 LEU A C   1 
ATOM   898   O O   . LEU A 1 278 ? 105.566 59.893  135.337 1.00 108.59 ? 277 LEU A O   1 
ATOM   899   C CB  . LEU A 1 278 ? 107.242 60.036  137.569 1.00 131.98 ? 277 LEU A CB  1 
ATOM   900   C CG  . LEU A 1 278 ? 107.850 60.397  138.909 1.00 182.85 ? 277 LEU A CG  1 
ATOM   901   C CD1 . LEU A 1 278 ? 109.085 61.270  138.709 1.00 190.44 ? 277 LEU A CD1 1 
ATOM   902   C CD2 . LEU A 1 278 ? 106.836 61.102  139.783 1.00 196.59 ? 277 LEU A CD2 1 
ATOM   903   N N   . LEU A 1 279 ? 105.188 57.702  135.881 1.00 144.65 ? 278 LEU A N   1 
ATOM   904   C CA  . LEU A 1 279 ? 105.032 57.269  134.518 1.00 151.97 ? 278 LEU A CA  1 
ATOM   905   C C   . LEU A 1 279 ? 103.558 56.954  134.285 1.00 157.66 ? 278 LEU A C   1 
ATOM   906   O O   . LEU A 1 279 ? 102.990 57.435  133.318 1.00 127.25 ? 278 LEU A O   1 
ATOM   907   C CB  . LEU A 1 279 ? 106.044 56.136  134.335 1.00 157.97 ? 278 LEU A CB  1 
ATOM   908   C CG  . LEU A 1 279 ? 106.414 55.882  132.898 1.00 182.57 ? 278 LEU A CG  1 
ATOM   909   C CD1 . LEU A 1 279 ? 107.826 55.306  132.810 1.00 205.52 ? 278 LEU A CD1 1 
ATOM   910   C CD2 . LEU A 1 279 ? 105.345 54.995  132.269 1.00 224.53 ? 278 LEU A CD2 1 
ATOM   911   N N   . GLN A 1 280 ? 102.918 56.158  135.148 1.00 162.03 ? 279 GLN A N   1 
ATOM   912   C CA  . GLN A 1 280 ? 101.493 55.865  134.983 1.00 167.69 ? 279 GLN A CA  1 
ATOM   913   C C   . GLN A 1 280 ? 100.699 57.103  135.398 1.00 143.00 ? 279 GLN A C   1 
ATOM   914   O O   . GLN A 1 280 ? 101.013 57.653  136.476 1.00 153.43 ? 279 GLN A O   1 
ATOM   915   C CB  . GLN A 1 280 ? 101.117 54.621  135.798 1.00 189.34 ? 279 GLN A CB  1 
ATOM   916   C CG  . GLN A 1 280 ? 99.618  54.350  135.875 1.00 234.81 ? 279 GLN A CG  1 
ATOM   917   C CD  . GLN A 1 280 ? 99.253  53.209  136.793 1.00 273.04 ? 279 GLN A CD  1 
ATOM   918   O OE1 . GLN A 1 280 ? 99.938  52.912  137.771 1.00 307.75 ? 279 GLN A OE1 1 
ATOM   919   N NE2 . GLN A 1 280 ? 98.147  52.557  136.482 1.00 292.83 ? 279 GLN A NE2 1 
ATOM   920   N N   . ILE A 1 281 ? 99.687  57.523  134.573 1.00 95.78  ? 280 ILE A N   1 
ATOM   921   C CA  . ILE A 1 281 ? 98.857  58.696  134.945 1.00 123.59 ? 280 ILE A CA  1 
ATOM   922   C C   . ILE A 1 281 ? 97.811  58.309  136.002 1.00 118.45 ? 280 ILE A C   1 
ATOM   923   O O   . ILE A 1 281 ? 97.357  57.162  136.031 1.00 141.43 ? 280 ILE A O   1 
ATOM   924   C CB  . ILE A 1 281 ? 98.242  59.469  133.743 1.00 108.60 ? 280 ILE A CB  1 
ATOM   925   C CG1 . ILE A 1 281 ? 97.075  58.788  133.093 1.00 137.40 ? 280 ILE A CG1 1 
ATOM   926   C CG2 . ILE A 1 281 ? 99.271  59.670  132.652 1.00 201.90 ? 280 ILE A CG2 1 
ATOM   927   C CD1 . ILE A 1 281 ? 95.787  59.295  133.541 1.00 143.65 ? 280 ILE A CD1 1 
ATOM   928   N N   . ASP A 1 282 ? 97.472  59.283  136.874 1.00 167.79 ? 281 ASP A N   1 
ATOM   929   C CA  . ASP A 1 282 ? 96.473  59.141  137.922 1.00 216.24 ? 281 ASP A CA  1 
ATOM   930   C C   . ASP A 1 282 ? 95.110  59.015  137.264 1.00 193.35 ? 281 ASP A C   1 
ATOM   931   O O   . ASP A 1 282 ? 94.693  59.992  136.647 1.00 184.08 ? 281 ASP A O   1 
ATOM   932   C CB  . ASP A 1 282 ? 96.524  60.337  138.884 1.00 251.27 ? 281 ASP A CB  1 
ATOM   933   C CG  . ASP A 1 282 ? 95.590  60.284  140.090 1.00 283.99 ? 281 ASP A CG  1 
ATOM   934   O OD1 . ASP A 1 282 ? 94.867  59.285  140.254 1.00 219.47 ? 281 ASP A OD1 1 
ATOM   935   O OD2 . ASP A 1 282 ? 95.580  61.254  140.856 1.00 343.08 ? 281 ASP A OD2 1 
ATOM   936   N N   . PRO A 1 283 ? 94.402  57.858  137.378 1.00 198.35 ? 282 PRO A N   1 
ATOM   937   C CA  . PRO A 1 283 ? 93.233  57.564  136.544 1.00 212.94 ? 282 PRO A CA  1 
ATOM   938   C C   . PRO A 1 283 ? 92.076  58.554  136.606 1.00 188.59 ? 282 PRO A C   1 
ATOM   939   O O   . PRO A 1 283 ? 91.302  58.570  135.642 1.00 181.30 ? 282 PRO A O   1 
ATOM   940   C CB  . PRO A 1 283 ? 92.723  56.190  137.035 1.00 238.00 ? 282 PRO A CB  1 
ATOM   941   C CG  . PRO A 1 283 ? 93.356  55.998  138.382 1.00 222.48 ? 282 PRO A CG  1 
ATOM   942   C CD  . PRO A 1 283 ? 94.675  56.740  138.296 1.00 207.38 ? 282 PRO A CD  1 
ATOM   943   N N   . ASN A 1 284 ? 91.979  59.349  137.697 1.00 195.23 ? 283 ASN A N   1 
ATOM   944   C CA  . ASN A 1 284 ? 91.011  60.439  137.823 1.00 197.48 ? 283 ASN A CA  1 
ATOM   945   C C   . ASN A 1 284 ? 90.996  61.328  136.581 1.00 177.67 ? 283 ASN A C   1 
ATOM   946   O O   . ASN A 1 284 ? 89.920  61.734  136.152 1.00 260.22 ? 283 ASN A O   1 
ATOM   947   C CB  . ASN A 1 284 ? 91.265  61.296  139.066 1.00 214.42 ? 283 ASN A CB  1 
ATOM   948   C CG  . ASN A 1 284 ? 91.072  60.515  140.348 1.00 297.13 ? 283 ASN A CG  1 
ATOM   949   O OD1 . ASN A 1 284 ? 90.702  59.340  140.317 1.00 302.65 ? 283 ASN A OD1 1 
ATOM   950   N ND2 . ASN A 1 284 ? 91.319  61.157  141.479 1.00 341.49 ? 283 ASN A ND2 1 
ATOM   951   N N   . PHE A 1 285 ? 92.178  61.605  136.008 1.00 147.14 ? 284 PHE A N   1 
ATOM   952   C CA  . PHE A 1 285 ? 92.317  62.491  134.860 1.00 190.47 ? 284 PHE A CA  1 
ATOM   953   C C   . PHE A 1 285 ? 92.090  61.796  133.517 1.00 179.98 ? 284 PHE A C   1 
ATOM   954   O O   . PHE A 1 285 ? 92.039  62.504  132.511 1.00 129.74 ? 284 PHE A O   1 
ATOM   955   C CB  . PHE A 1 285 ? 93.704  63.129  134.831 1.00 196.78 ? 284 PHE A CB  1 
ATOM   956   C CG  . PHE A 1 285 ? 94.078  63.874  136.085 1.00 173.94 ? 284 PHE A CG  1 
ATOM   957   C CD1 . PHE A 1 285 ? 93.268  64.887  136.570 1.00 180.86 ? 284 PHE A CD1 1 
ATOM   958   C CD2 . PHE A 1 285 ? 95.245  63.570  136.769 1.00 180.13 ? 284 PHE A CD2 1 
ATOM   959   C CE1 . PHE A 1 285 ? 93.597  65.574  137.729 1.00 205.05 ? 284 PHE A CE1 1 
ATOM   960   C CE2 . PHE A 1 285 ? 95.567  64.260  137.929 1.00 186.57 ? 284 PHE A CE2 1 
ATOM   961   C CZ  . PHE A 1 285 ? 94.749  65.268  138.399 1.00 184.27 ? 284 PHE A CZ  1 
ATOM   962   N N   . GLY A 1 286 ? 91.940  60.463  133.477 1.00 169.56 ? 285 GLY A N   1 
ATOM   963   C CA  . GLY A 1 286 ? 91.695  59.749  132.229 1.00 186.84 ? 285 GLY A CA  1 
ATOM   964   C C   . GLY A 1 286 ? 92.583  58.514  132.048 1.00 169.42 ? 285 GLY A C   1 
ATOM   965   O O   . GLY A 1 286 ? 92.702  57.693  132.964 1.00 157.35 ? 285 GLY A O   1 
ATOM   966   N N   . SER A 1 287 ? 93.201  58.414  130.853 1.00 135.76 ? 286 SER A N   1 
ATOM   967   C CA  . SER A 1 287 ? 94.077  57.322  130.438 1.00 149.13 ? 286 SER A CA  1 
ATOM   968   C C   . SER A 1 287 ? 95.177  57.860  129.529 1.00 163.10 ? 286 SER A C   1 
ATOM   969   O O   . SER A 1 287 ? 95.023  58.967  129.003 1.00 141.48 ? 286 SER A O   1 
ATOM   970   C CB  . SER A 1 287 ? 93.280  56.343  129.652 1.00 243.57 ? 286 SER A CB  1 
ATOM   971   O OG  . SER A 1 287 ? 92.795  56.949  128.439 1.00 245.86 ? 286 SER A OG  1 
ATOM   972   N N   . LYS A 1 288 ? 96.279  57.114  129.325 1.00 150.09 ? 287 LYS A N   1 
ATOM   973   C CA  . LYS A 1 288 ? 97.285  57.590  128.372 1.00 189.80 ? 287 LYS A CA  1 
ATOM   974   C C   . LYS A 1 288 ? 96.673  57.800  126.969 1.00 181.02 ? 287 LYS A C   1 
ATOM   975   O O   . LYS A 1 288 ? 97.106  58.685  126.224 1.00 179.94 ? 287 LYS A O   1 
ATOM   976   C CB  . LYS A 1 288 ? 98.520  56.684  128.338 1.00 187.89 ? 287 LYS A CB  1 
ATOM   977   C CG  . LYS A 1 288 ? 99.529  57.076  127.257 1.00 190.34 ? 287 LYS A CG  1 
ATOM   978   C CD  . LYS A 1 288 ? 100.978 56.803  127.589 1.00 212.36 ? 287 LYS A CD  1 
ATOM   979   C CE  . LYS A 1 288 ? 101.869 56.610  126.371 1.00 222.96 ? 287 LYS A CE  1 
ATOM   980   N NZ  . LYS A 1 288 ? 101.641 57.585  125.279 1.00 213.52 ? 287 LYS A NZ  1 
ATOM   981   N N   . GLU A 1 289 ? 95.651  57.008  126.623 1.00 202.85 ? 288 GLU A N   1 
ATOM   982   C CA  . GLU A 1 289 ? 94.922  57.157  125.371 1.00 231.71 ? 288 GLU A CA  1 
ATOM   983   C C   . GLU A 1 289 ? 94.207  58.514  125.294 1.00 216.65 ? 288 GLU A C   1 
ATOM   984   O O   . GLU A 1 289 ? 94.113  59.067  124.193 1.00 183.04 ? 288 GLU A O   1 
ATOM   985   C CB  . GLU A 1 289 ? 93.949  55.988  125.204 1.00 311.34 ? 288 GLU A CB  1 
ATOM   986   C CG  . GLU A 1 289 ? 94.643  54.663  124.896 1.00 384.35 ? 288 GLU A CG  1 
ATOM   987   C CD  . GLU A 1 289 ? 95.491  54.028  125.991 1.00 421.36 ? 288 GLU A CD  1 
ATOM   988   O OE1 . GLU A 1 289 ? 95.251  54.310  127.185 1.00 426.45 ? 288 GLU A OE1 1 
ATOM   989   O OE2 . GLU A 1 289 ? 96.403  53.254  125.646 1.00 469.16 ? 288 GLU A OE2 1 
ATOM   990   N N   . ASP A 1 290 ? 93.714  59.042  126.433 1.00 187.74 ? 289 ASP A N   1 
ATOM   991   C CA  . ASP A 1 290 ? 93.218  60.412  126.480 1.00 203.16 ? 289 ASP A CA  1 
ATOM   992   C C   . ASP A 1 290 ? 94.361  61.411  126.339 1.00 180.29 ? 289 ASP A C   1 
ATOM   993   O O   . ASP A 1 290 ? 94.227  62.385  125.587 1.00 130.06 ? 289 ASP A O   1 
ATOM   994   C CB  . ASP A 1 290 ? 92.470  60.726  127.775 1.00 225.90 ? 289 ASP A CB  1 
ATOM   995   C CG  . ASP A 1 290 ? 91.287  59.817  128.007 1.00 277.86 ? 289 ASP A CG  1 
ATOM   996   O OD1 . ASP A 1 290 ? 90.361  59.818  127.170 1.00 378.24 ? 289 ASP A OD1 1 
ATOM   997   O OD2 . ASP A 1 290 ? 91.323  59.122  129.014 1.00 195.87 ? 289 ASP A OD2 1 
ATOM   998   N N   . PHE A 1 291 ? 95.458  61.164  127.082 1.00 176.18 ? 290 PHE A N   1 
ATOM   999   C CA  . PHE A 1 291 ? 96.591  62.082  127.135 1.00 165.19 ? 290 PHE A CA  1 
ATOM   1000  C C   . PHE A 1 291 ? 97.095  62.341  125.713 1.00 133.96 ? 290 PHE A C   1 
ATOM   1001  O O   . PHE A 1 291 ? 97.277  63.491  125.311 1.00 152.52 ? 290 PHE A O   1 
ATOM   1002  C CB  . PHE A 1 291 ? 97.691  61.584  128.099 1.00 146.79 ? 290 PHE A CB  1 
ATOM   1003  C CG  . PHE A 1 291 ? 98.768  62.632  128.273 1.00 156.10 ? 290 PHE A CG  1 
ATOM   1004  C CD1 . PHE A 1 291 ? 98.563  63.746  129.072 1.00 216.95 ? 290 PHE A CD1 1 
ATOM   1005  C CD2 . PHE A 1 291 ? 99.961  62.558  127.586 1.00 131.66 ? 290 PHE A CD2 1 
ATOM   1006  C CE1 . PHE A 1 291 ? 99.539  64.730  129.211 1.00 206.11 ? 290 PHE A CE1 1 
ATOM   1007  C CE2 . PHE A 1 291 ? 100.926 63.536  127.728 1.00 160.15 ? 290 PHE A CE2 1 
ATOM   1008  C CZ  . PHE A 1 291 ? 100.725 64.621  128.534 1.00 167.89 ? 290 PHE A CZ  1 
ATOM   1009  N N   . ASP A 1 292 ? 97.298  61.251  124.973 1.00 149.53 ? 291 ASP A N   1 
ATOM   1010  C CA  . ASP A 1 292 ? 97.771  61.330  123.604 1.00 182.91 ? 291 ASP A CA  1 
ATOM   1011  C C   . ASP A 1 292 ? 96.738  62.050  122.738 1.00 139.64 ? 291 ASP A C   1 
ATOM   1012  O O   . ASP A 1 292 ? 97.128  62.764  121.823 1.00 135.97 ? 291 ASP A O   1 
ATOM   1013  C CB  . ASP A 1 292 ? 98.113  59.931  123.075 1.00 238.89 ? 291 ASP A CB  1 
ATOM   1014  C CG  . ASP A 1 292 ? 99.268  59.245  123.796 1.00 249.90 ? 291 ASP A CG  1 
ATOM   1015  O OD1 . ASP A 1 292 ? 100.105 59.971  124.387 1.00 309.55 ? 291 ASP A OD1 1 
ATOM   1016  O OD2 . ASP A 1 292 ? 99.332  57.983  123.779 1.00 194.23 ? 291 ASP A OD2 1 
ATOM   1017  N N   . SER A 1 293 ? 95.444  61.855  123.014 1.00 118.72 ? 292 SER A N   1 
ATOM   1018  C CA  . SER A 1 293 ? 94.390  62.449  122.215 1.00 185.70 ? 292 SER A CA  1 
ATOM   1019  C C   . SER A 1 293 ? 94.457  63.960  122.333 1.00 143.54 ? 292 SER A C   1 
ATOM   1020  O O   . SER A 1 293 ? 94.341  64.642  121.321 1.00 114.44 ? 292 SER A O   1 
ATOM   1021  C CB  . SER A 1 293 ? 93.021  61.912  122.598 1.00 244.20 ? 292 SER A CB  1 
ATOM   1022  O OG  . SER A 1 293 ? 92.028  62.375  121.700 1.00 316.21 ? 292 SER A OG  1 
ATOM   1023  N N   . LEU A 1 294 ? 94.616  64.439  123.579 1.00 166.82 ? 293 LEU A N   1 
ATOM   1024  C CA  . LEU A 1 294 ? 94.882  65.845  123.890 1.00 163.34 ? 293 LEU A CA  1 
ATOM   1025  C C   . LEU A 1 294 ? 96.133  66.340  123.177 1.00 113.74 ? 293 LEU A C   1 
ATOM   1026  O O   . LEU A 1 294 ? 96.086  67.303  122.425 1.00 82.10  ? 293 LEU A O   1 
ATOM   1027  C CB  . LEU A 1 294 ? 95.027  66.022  125.411 1.00 133.62 ? 293 LEU A CB  1 
ATOM   1028  C CG  . LEU A 1 294 ? 95.817  67.231  125.925 1.00 143.65 ? 293 LEU A CG  1 
ATOM   1029  C CD1 . LEU A 1 294 ? 95.338  68.643  125.451 1.00 121.59 ? 293 LEU A CD1 1 
ATOM   1030  C CD2 . LEU A 1 294 ? 95.753  67.096  127.436 1.00 136.68 ? 293 LEU A CD2 1 
ATOM   1031  N N   . LEU A 1 295 ? 97.229  65.644  123.451 1.00 131.80 ? 294 LEU A N   1 
ATOM   1032  C CA  . LEU A 1 295 ? 98.544  66.110  123.065 1.00 107.69 ? 294 LEU A CA  1 
ATOM   1033  C C   . LEU A 1 295 ? 98.599  66.255  121.533 1.00 121.15 ? 294 LEU A C   1 
ATOM   1034  O O   . LEU A 1 295 ? 99.168  67.224  121.032 1.00 98.68  ? 294 LEU A O   1 
ATOM   1035  C CB  . LEU A 1 295 ? 99.526  65.108  123.712 1.00 120.76 ? 294 LEU A CB  1 
ATOM   1036  C CG  . LEU A 1 295 ? 100.994 65.197  123.317 1.00 157.02 ? 294 LEU A CG  1 
ATOM   1037  C CD1 . LEU A 1 295 ? 101.557 66.587  123.543 1.00 232.41 ? 294 LEU A CD1 1 
ATOM   1038  C CD2 . LEU A 1 295 ? 101.817 64.191  124.100 1.00 141.38 ? 294 LEU A CD2 1 
ATOM   1039  N N   . GLN A 1 296 ? 97.989  65.300  120.798 1.00 168.84 ? 295 GLN A N   1 
ATOM   1040  C CA  . GLN A 1 296 ? 97.855  65.327  119.348 1.00 173.61 ? 295 GLN A CA  1 
ATOM   1041  C C   . GLN A 1 296 ? 96.977  66.504  118.919 1.00 127.42 ? 295 GLN A C   1 
ATOM   1042  O O   . GLN A 1 296 ? 97.241  67.113  117.882 1.00 196.39 ? 295 GLN A O   1 
ATOM   1043  C CB  . GLN A 1 296 ? 97.284  63.984  118.875 1.00 189.22 ? 295 GLN A CB  1 
ATOM   1044  C CG  . GLN A 1 296 ? 97.198  63.798  117.367 1.00 285.36 ? 295 GLN A CG  1 
ATOM   1045  C CD  . GLN A 1 296 ? 96.290  62.666  116.941 1.00 331.97 ? 295 GLN A CD  1 
ATOM   1046  O OE1 . GLN A 1 296 ? 95.437  62.196  117.694 1.00 321.27 ? 295 GLN A OE1 1 
ATOM   1047  N NE2 . GLN A 1 296 ? 96.462  62.221  115.705 1.00 388.86 ? 295 GLN A NE2 1 
ATOM   1048  N N   . SER A 1 297 ? 95.916  66.817  119.674 1.00 93.74  ? 296 SER A N   1 
ATOM   1049  C CA  . SER A 1 297 ? 95.057  67.954  119.351 1.00 130.82 ? 296 SER A CA  1 
ATOM   1050  C C   . SER A 1 297 ? 95.800  69.273  119.532 1.00 144.88 ? 296 SER A C   1 
ATOM   1051  O O   . SER A 1 297 ? 95.658  70.216  118.757 1.00 140.18 ? 296 SER A O   1 
ATOM   1052  C CB  . SER A 1 297 ? 93.794  67.959  120.159 1.00 125.02 ? 296 SER A CB  1 
ATOM   1053  O OG  . SER A 1 297 ? 93.095  66.743  119.987 1.00 196.66 ? 296 SER A OG  1 
ATOM   1054  N N   . ALA A 1 298 ? 96.596  69.323  120.588 1.00 149.65 ? 297 ALA A N   1 
ATOM   1055  C CA  . ALA A 1 298 ? 97.330  70.524  120.883 1.00 119.97 ? 297 ALA A CA  1 
ATOM   1056  C C   . ALA A 1 298 ? 98.360  70.736  119.775 1.00 136.84 ? 297 ALA A C   1 
ATOM   1057  O O   . ALA A 1 298 ? 98.501  71.868  119.343 1.00 139.40 ? 297 ALA A O   1 
ATOM   1058  C CB  . ALA A 1 298 ? 97.904  70.364  122.266 1.00 124.87 ? 297 ALA A CB  1 
ATOM   1059  N N   . LYS A 1 299 ? 99.081  69.685  119.318 1.00 163.44 ? 298 LYS A N   1 
ATOM   1060  C CA  . LYS A 1 299 ? 100.008 69.780  118.183 1.00 179.36 ? 298 LYS A CA  1 
ATOM   1061  C C   . LYS A 1 299 ? 99.275  70.344  116.980 1.00 157.43 ? 298 LYS A C   1 
ATOM   1062  O O   . LYS A 1 299 ? 99.782  71.281  116.355 1.00 220.39 ? 298 LYS A O   1 
ATOM   1063  C CB  . LYS A 1 299 ? 100.701 68.462  117.803 1.00 179.53 ? 298 LYS A CB  1 
ATOM   1064  C CG  . LYS A 1 299 ? 102.066 68.243  118.466 1.00 285.64 ? 298 LYS A CG  1 
ATOM   1065  C CD  . LYS A 1 299 ? 102.033 68.015  119.981 1.00 348.30 ? 298 LYS A CD  1 
ATOM   1066  C CE  . LYS A 1 299 ? 103.241 68.507  120.759 1.00 365.62 ? 298 LYS A CE  1 
ATOM   1067  N NZ  . LYS A 1 299 ? 104.492 67.744  120.535 1.00 362.28 ? 298 LYS A NZ  1 
ATOM   1068  N N   . LYS A 1 300 ? 98.097  69.780  116.696 1.00 156.55 ? 299 LYS A N   1 
ATOM   1069  C CA  . LYS A 1 300 ? 97.229  70.236  115.606 1.00 261.75 ? 299 LYS A CA  1 
ATOM   1070  C C   . LYS A 1 300 ? 96.905  71.741  115.730 1.00 204.97 ? 299 LYS A C   1 
ATOM   1071  O O   . LYS A 1 300 ? 96.811  72.430  114.706 1.00 170.31 ? 299 LYS A O   1 
ATOM   1072  C CB  . LYS A 1 300 ? 95.991  69.316  115.522 1.00 289.03 ? 299 LYS A CB  1 
ATOM   1073  C CG  . LYS A 1 300 ? 94.789  69.777  114.701 1.00 284.45 ? 299 LYS A CG  1 
ATOM   1074  C CD  . LYS A 1 300 ? 95.076  69.958  113.227 1.00 420.38 ? 299 LYS A CD  1 
ATOM   1075  C CE  . LYS A 1 300 ? 93.904  70.527  112.455 1.00 490.17 ? 299 LYS A CE  1 
ATOM   1076  N NZ  . LYS A 1 300 ? 94.264  70.828  111.048 1.00 515.23 ? 299 LYS A NZ  1 
ATOM   1077  N N   . LYS A 1 301 ? 96.739  72.260  116.960 1.00 133.89 ? 300 LYS A N   1 
ATOM   1078  C CA  . LYS A 1 301 ? 96.322  73.647  117.181 1.00 139.27 ? 300 LYS A CA  1 
ATOM   1079  C C   . LYS A 1 301 ? 97.510  74.599  117.508 1.00 163.54 ? 300 LYS A C   1 
ATOM   1080  O O   . LYS A 1 301 ? 97.264  75.783  117.813 1.00 127.54 ? 300 LYS A O   1 
ATOM   1081  C CB  . LYS A 1 301 ? 95.198  73.576  118.242 1.00 145.63 ? 300 LYS A CB  1 
ATOM   1082  C CG  . LYS A 1 301 ? 94.050  74.521  117.995 1.00 166.10 ? 300 LYS A CG  1 
ATOM   1083  C CD  . LYS A 1 301 ? 92.916  74.469  119.007 1.00 155.77 ? 300 LYS A CD  1 
ATOM   1084  C CE  . LYS A 1 301 ? 91.632  75.105  118.470 1.00 253.76 ? 300 LYS A CE  1 
ATOM   1085  N NZ  . LYS A 1 301 ? 91.821  76.418  117.778 1.00 256.11 ? 300 LYS A NZ  1 
ATOM   1086  N N   . SER A 1 302 ? 98.784  74.101  117.459 1.00 169.76 ? 301 SER A N   1 
ATOM   1087  C CA  . SER A 1 302 ? 100.044 74.840  117.699 1.00 171.36 ? 301 SER A CA  1 
ATOM   1088  C C   . SER A 1 302 ? 100.286 75.294  119.164 1.00 164.02 ? 301 SER A C   1 
ATOM   1089  O O   . SER A 1 302 ? 101.062 76.202  119.461 1.00 180.91 ? 301 SER A O   1 
ATOM   1090  C CB  . SER A 1 302 ? 100.175 76.001  116.737 1.00 220.94 ? 301 SER A CB  1 
ATOM   1091  O OG  . SER A 1 302 ? 100.100 75.546  115.397 1.00 280.67 ? 301 SER A OG  1 
ATOM   1092  N N   . ILE A 1 303 ? 99.649  74.627  120.107 1.00 120.98 ? 302 ILE A N   1 
ATOM   1093  C CA  . ILE A 1 303 ? 99.883  74.748  121.534 1.00 86.23  ? 302 ILE A CA  1 
ATOM   1094  C C   . ILE A 1 303 ? 100.824 73.619  121.955 1.00 97.22  ? 302 ILE A C   1 
ATOM   1095  O O   . ILE A 1 303 ? 100.413 72.466  122.089 1.00 85.86  ? 302 ILE A O   1 
ATOM   1096  C CB  . ILE A 1 303 ? 98.477  74.610  122.181 1.00 103.09 ? 302 ILE A CB  1 
ATOM   1097  C CG1 . ILE A 1 303 ? 97.677  75.856  121.774 1.00 121.91 ? 302 ILE A CG1 1 
ATOM   1098  C CG2 . ILE A 1 303 ? 98.403  74.336  123.703 1.00 96.82  ? 302 ILE A CG2 1 
ATOM   1099  C CD1 . ILE A 1 303 ? 96.505  76.144  122.716 1.00 126.92 ? 302 ILE A CD1 1 
ATOM   1100  N N   . ARG A 1 304 ? 102.100 73.886  122.177 1.00 99.82  ? 303 ARG A N   1 
ATOM   1101  C CA  . ARG A 1 304 ? 102.958 72.831  122.711 1.00 102.35 ? 303 ARG A CA  1 
ATOM   1102  C C   . ARG A 1 304 ? 102.448 72.469  124.114 1.00 72.36  ? 303 ARG A C   1 
ATOM   1103  O O   . ARG A 1 304 ? 101.955 73.359  124.811 1.00 61.08  ? 303 ARG A O   1 
ATOM   1104  C CB  . ARG A 1 304 ? 104.435 73.301  122.705 1.00 141.58 ? 303 ARG A CB  1 
ATOM   1105  C CG  . ARG A 1 304 ? 105.211 73.126  121.393 1.00 130.41 ? 303 ARG A CG  1 
ATOM   1106  C CD  . ARG A 1 304 ? 104.784 74.074  120.346 1.00 139.41 ? 303 ARG A CD  1 
ATOM   1107  N NE  . ARG A 1 304 ? 105.709 74.050  119.237 1.00 139.56 ? 303 ARG A NE  1 
ATOM   1108  C CZ  . ARG A 1 304 ? 105.654 74.985  118.288 1.00 247.52 ? 303 ARG A CZ  1 
ATOM   1109  N NH1 . ARG A 1 304 ? 106.540 74.983  117.303 1.00 336.21 ? 303 ARG A NH1 1 
ATOM   1110  N NH2 . ARG A 1 304 ? 104.707 75.929  118.333 1.00 184.74 ? 303 ARG A NH2 1 
ATOM   1111  N N   . VAL A 1 305 ? 102.602 71.218  124.551 1.00 54.96  ? 304 VAL A N   1 
ATOM   1112  C CA  . VAL A 1 305 ? 102.328 70.855  125.950 1.00 57.77  ? 304 VAL A CA  1 
ATOM   1113  C C   . VAL A 1 305 ? 103.470 70.357  126.831 1.00 55.36  ? 304 VAL A C   1 
ATOM   1114  O O   . VAL A 1 305 ? 104.047 69.316  126.541 1.00 111.23 ? 304 VAL A O   1 
ATOM   1115  C CB  . VAL A 1 305 ? 101.338 69.693  125.872 1.00 60.28  ? 304 VAL A CB  1 
ATOM   1116  C CG1 . VAL A 1 305 ? 101.010 68.912  127.211 1.00 42.82  ? 304 VAL A CG1 1 
ATOM   1117  C CG2 . VAL A 1 305 ? 100.145 70.253  125.084 1.00 63.54  ? 304 VAL A CG2 1 
ATOM   1118  N N   . ILE A 1 306 ? 103.746 71.038  127.922 1.00 46.46  ? 305 ILE A N   1 
ATOM   1119  C CA  . ILE A 1 306 ? 104.670 70.548  128.937 1.00 61.30  ? 305 ILE A CA  1 
ATOM   1120  C C   . ILE A 1 306 ? 103.963 69.829  130.070 1.00 50.15  ? 305 ILE A C   1 
ATOM   1121  O O   . ILE A 1 306 ? 102.894 70.203  130.485 1.00 78.46  ? 305 ILE A O   1 
ATOM   1122  C CB  . ILE A 1 306 ? 105.391 71.761  129.507 1.00 57.19  ? 305 ILE A CB  1 
ATOM   1123  C CG1 . ILE A 1 306 ? 106.214 72.441  128.431 1.00 57.31  ? 305 ILE A CG1 1 
ATOM   1124  C CG2 . ILE A 1 306 ? 106.244 71.381  130.663 1.00 49.21  ? 305 ILE A CG2 1 
ATOM   1125  C CD1 . ILE A 1 306 ? 106.263 73.973  128.732 1.00 61.95  ? 305 ILE A CD1 1 
ATOM   1126  N N   . LEU A 1 307 ? 104.590 68.846  130.637 1.00 43.80  ? 306 LEU A N   1 
ATOM   1127  C CA  . LEU A 1 307 ? 103.964 68.146  131.732 1.00 59.05  ? 306 LEU A CA  1 
ATOM   1128  C C   . LEU A 1 307 ? 104.827 68.400  132.956 1.00 57.93  ? 306 LEU A C   1 
ATOM   1129  O O   . LEU A 1 307 ? 106.047 68.467  132.886 1.00 41.65  ? 306 LEU A O   1 
ATOM   1130  C CB  . LEU A 1 307 ? 103.886 66.672  131.316 1.00 82.45  ? 306 LEU A CB  1 
ATOM   1131  C CG  . LEU A 1 307 ? 103.961 65.608  132.404 1.00 82.64  ? 306 LEU A CG  1 
ATOM   1132  C CD1 . LEU A 1 307 ? 102.601 65.411  132.952 1.00 141.02 ? 306 LEU A CD1 1 
ATOM   1133  C CD2 . LEU A 1 307 ? 104.434 64.288  131.845 1.00 98.60  ? 306 LEU A CD2 1 
ATOM   1134  N N   . ASP A 1 308 ? 104.174 68.556  134.089 1.00 71.39  ? 307 ASP A N   1 
ATOM   1135  C CA  . ASP A 1 308 ? 104.844 68.843  135.344 1.00 73.65  ? 307 ASP A CA  1 
ATOM   1136  C C   . ASP A 1 308 ? 105.103 67.541  136.089 1.00 78.83  ? 307 ASP A C   1 
ATOM   1137  O O   . ASP A 1 308 ? 104.209 66.804  136.440 1.00 86.99  ? 307 ASP A O   1 
ATOM   1138  C CB  . ASP A 1 308 ? 103.932 69.705  136.196 1.00 105.59 ? 307 ASP A CB  1 
ATOM   1139  C CG  . ASP A 1 308 ? 104.576 70.305  137.422 1.00 126.43 ? 307 ASP A CG  1 
ATOM   1140  O OD1 . ASP A 1 308 ? 105.542 69.713  137.921 1.00 141.26 ? 307 ASP A OD1 1 
ATOM   1141  O OD2 . ASP A 1 308 ? 104.071 71.379  137.859 1.00 192.24 ? 307 ASP A OD2 1 
ATOM   1142  N N   . LEU A 1 309 ? 106.344 67.259  136.384 1.00 86.14  ? 308 LEU A N   1 
ATOM   1143  C CA  . LEU A 1 309 ? 106.724 66.004  136.990 1.00 81.14  ? 308 LEU A CA  1 
ATOM   1144  C C   . LEU A 1 309 ? 107.198 66.132  138.438 1.00 88.86  ? 308 LEU A C   1 
ATOM   1145  O O   . LEU A 1 309 ? 107.926 65.255  138.931 1.00 90.33  ? 308 LEU A O   1 
ATOM   1146  C CB  . LEU A 1 309 ? 107.899 65.495  136.184 1.00 88.91  ? 308 LEU A CB  1 
ATOM   1147  C CG  . LEU A 1 309 ? 107.545 65.117  134.763 1.00 108.16 ? 308 LEU A CG  1 
ATOM   1148  C CD1 . LEU A 1 309 ? 108.873 64.801  134.105 1.00 141.51 ? 308 LEU A CD1 1 
ATOM   1149  C CD2 . LEU A 1 309 ? 106.572 63.945  134.754 1.00 102.21 ? 308 LEU A CD2 1 
ATOM   1150  N N   . THR A 1 310 ? 106.796 67.194  139.141 1.00 84.44  ? 309 THR A N   1 
ATOM   1151  C CA  . THR A 1 310 ? 107.251 67.336  140.514 1.00 107.65 ? 309 THR A CA  1 
ATOM   1152  C C   . THR A 1 310 ? 106.633 66.175  141.317 1.00 105.21 ? 309 THR A C   1 
ATOM   1153  O O   . THR A 1 310 ? 105.431 66.026  141.389 1.00 73.65  ? 309 THR A O   1 
ATOM   1154  C CB  . THR A 1 310 ? 106.951 68.720  141.073 1.00 90.11  ? 309 THR A CB  1 
ATOM   1155  O OG1 . THR A 1 310 ? 107.621 68.768  142.327 1.00 169.12 ? 309 THR A OG1 1 
ATOM   1156  C CG2 . THR A 1 310 ? 105.503 68.970  141.352 1.00 102.80 ? 309 THR A CG2 1 
ATOM   1157  N N   . PRO A 1 311 ? 107.428 65.265  141.902 1.00 98.34  ? 310 PRO A N   1 
ATOM   1158  C CA  . PRO A 1 311 ? 106.881 63.964  142.308 1.00 89.88  ? 310 PRO A CA  1 
ATOM   1159  C C   . PRO A 1 311 ? 105.734 63.948  143.307 1.00 96.26  ? 310 PRO A C   1 
ATOM   1160  O O   . PRO A 1 311 ? 104.703 63.379  142.976 1.00 125.41 ? 310 PRO A O   1 
ATOM   1161  C CB  . PRO A 1 311 ? 108.088 63.293  142.934 1.00 119.76 ? 310 PRO A CB  1 
ATOM   1162  C CG  . PRO A 1 311 ? 109.255 63.994  142.247 1.00 113.58 ? 310 PRO A CG  1 
ATOM   1163  C CD  . PRO A 1 311 ? 108.867 65.437  142.143 1.00 77.99  ? 310 PRO A CD  1 
ATOM   1164  N N   . ASN A 1 312 ? 105.883 64.544  144.501 1.00 94.59  ? 311 ASN A N   1 
ATOM   1165  C CA  . ASN A 1 312 ? 104.947 64.304  145.595 1.00 134.34 ? 311 ASN A CA  1 
ATOM   1166  C C   . ASN A 1 312 ? 103.892 65.398  145.619 1.00 115.17 ? 311 ASN A C   1 
ATOM   1167  O O   . ASN A 1 312 ? 103.628 65.988  146.663 1.00 132.38 ? 311 ASN A O   1 
ATOM   1168  C CB  . ASN A 1 312 ? 105.669 64.279  146.943 1.00 138.30 ? 311 ASN A CB  1 
ATOM   1169  C CG  . ASN A 1 312 ? 104.827 63.889  148.145 1.00 162.55 ? 311 ASN A CG  1 
ATOM   1170  O OD1 . ASN A 1 312 ? 103.834 63.167  148.043 1.00 179.37 ? 311 ASN A OD1 1 
ATOM   1171  N ND2 . ASN A 1 312 ? 105.222 64.369  149.317 1.00 248.20 ? 311 ASN A ND2 1 
ATOM   1172  N N   . TYR A 1 313 ? 103.276 65.670  144.481 1.00 80.50  ? 312 TYR A N   1 
ATOM   1173  C CA  . TYR A 1 313 ? 102.540 66.899  144.347 1.00 101.40 ? 312 TYR A CA  1 
ATOM   1174  C C   . TYR A 1 313 ? 101.281 66.981  145.206 1.00 135.62 ? 312 TYR A C   1 
ATOM   1175  O O   . TYR A 1 313 ? 100.788 68.107  145.393 1.00 155.66 ? 312 TYR A O   1 
ATOM   1176  C CB  . TYR A 1 313 ? 102.157 67.034  142.888 1.00 117.70 ? 312 TYR A CB  1 
ATOM   1177  C CG  . TYR A 1 313 ? 101.170 66.050  142.278 1.00 96.63  ? 312 TYR A CG  1 
ATOM   1178  C CD1 . TYR A 1 313 ? 101.629 64.911  141.676 1.00 125.63 ? 312 TYR A CD1 1 
ATOM   1179  C CD2 . TYR A 1 313 ? 99.813  66.277  142.265 1.00 121.58 ? 312 TYR A CD2 1 
ATOM   1180  C CE1 . TYR A 1 313 ? 100.784 64.002  141.079 1.00 150.87 ? 312 TYR A CE1 1 
ATOM   1181  C CE2 . TYR A 1 313 ? 98.948  65.376  141.679 1.00 145.02 ? 312 TYR A CE2 1 
ATOM   1182  C CZ  . TYR A 1 313 ? 99.431  64.224  141.089 1.00 163.77 ? 312 TYR A CZ  1 
ATOM   1183  O OH  . TYR A 1 313 ? 98.591  63.313  140.520 1.00 219.16 ? 312 TYR A OH  1 
ATOM   1184  N N   . ARG A 1 314 ? 100.756 65.838  145.687 1.00 122.06 ? 313 ARG A N   1 
ATOM   1185  C CA  . ARG A 1 314 ? 99.620  65.859  146.595 1.00 164.92 ? 313 ARG A CA  1 
ATOM   1186  C C   . ARG A 1 314 ? 100.066 66.082  148.035 1.00 158.66 ? 313 ARG A C   1 
ATOM   1187  O O   . ARG A 1 314 ? 99.198  66.248  148.894 1.00 242.70 ? 313 ARG A O   1 
ATOM   1188  C CB  . ARG A 1 314 ? 98.820  64.561  146.444 1.00 181.30 ? 313 ARG A CB  1 
ATOM   1189  C CG  . ARG A 1 314 ? 98.262  64.378  145.039 1.00 163.44 ? 313 ARG A CG  1 
ATOM   1190  C CD  . ARG A 1 314 ? 97.211  63.308  144.953 1.00 186.27 ? 313 ARG A CD  1 
ATOM   1191  N NE  . ARG A 1 314 ? 96.595  63.216  143.637 1.00 187.20 ? 313 ARG A NE  1 
ATOM   1192  C CZ  . ARG A 1 314 ? 95.768  64.111  143.057 1.00 229.78 ? 313 ARG A CZ  1 
ATOM   1193  N NH1 . ARG A 1 314 ? 95.272  63.840  141.851 1.00 267.58 ? 313 ARG A NH1 1 
ATOM   1194  N NH2 . ARG A 1 314 ? 95.436  65.259  143.647 1.00 173.05 ? 313 ARG A NH2 1 
ATOM   1195  N N   . GLY A 1 315 ? 101.385 66.079  148.299 1.00 146.74 ? 314 GLY A N   1 
ATOM   1196  C CA  . GLY A 1 315 ? 101.920 66.106  149.653 1.00 221.11 ? 314 GLY A CA  1 
ATOM   1197  C C   . GLY A 1 315 ? 102.373 67.489  150.108 1.00 217.73 ? 314 GLY A C   1 
ATOM   1198  O O   . GLY A 1 315 ? 102.056 68.501  149.475 1.00 235.72 ? 314 GLY A O   1 
ATOM   1199  N N   . GLU A 1 316 ? 103.108 67.479  151.230 1.00 179.18 ? 315 GLU A N   1 
ATOM   1200  C CA  . GLU A 1 316 ? 103.576 68.677  151.897 1.00 221.79 ? 315 GLU A CA  1 
ATOM   1201  C C   . GLU A 1 316 ? 104.888 69.121  151.261 1.00 176.87 ? 315 GLU A C   1 
ATOM   1202  O O   . GLU A 1 316 ? 105.028 70.281  150.874 1.00 222.33 ? 315 GLU A O   1 
ATOM   1203  C CB  . GLU A 1 316 ? 103.733 68.405  153.393 1.00 316.37 ? 315 GLU A CB  1 
ATOM   1204  C CG  . GLU A 1 316 ? 104.205 69.619  154.183 1.00 453.52 ? 315 GLU A CG  1 
ATOM   1205  C CD  . GLU A 1 316 ? 104.096 69.529  155.699 1.00 562.27 ? 315 GLU A CD  1 
ATOM   1206  O OE1 . GLU A 1 316 ? 103.700 68.462  156.217 1.00 610.19 ? 315 GLU A OE1 1 
ATOM   1207  O OE2 . GLU A 1 316 ? 104.411 70.536  156.366 1.00 614.77 ? 315 GLU A OE2 1 
ATOM   1208  N N   . ASN A 1 317 ? 105.842 68.190  151.172 1.00 163.81 ? 316 ASN A N   1 
ATOM   1209  C CA  . ASN A 1 317 ? 107.152 68.442  150.587 1.00 201.52 ? 316 ASN A CA  1 
ATOM   1210  C C   . ASN A 1 317 ? 107.224 67.735  149.235 1.00 173.37 ? 316 ASN A C   1 
ATOM   1211  O O   . ASN A 1 317 ? 107.112 66.515  149.174 1.00 187.63 ? 316 ASN A O   1 
ATOM   1212  C CB  . ASN A 1 317 ? 108.263 68.012  151.553 1.00 205.56 ? 316 ASN A CB  1 
ATOM   1213  C CG  . ASN A 1 317 ? 109.666 68.104  150.980 1.00 229.28 ? 316 ASN A CG  1 
ATOM   1214  O OD1 . ASN A 1 317 ? 109.868 68.127  149.768 1.00 147.87 ? 316 ASN A OD1 1 
ATOM   1215  N ND2 . ASN A 1 317 ? 110.664 68.143  151.849 1.00 271.32 ? 316 ASN A ND2 1 
ATOM   1216  N N   . SER A 1 318 ? 107.426 68.500  148.143 1.00 136.19 ? 317 SER A N   1 
ATOM   1217  C CA  . SER A 1 318 ? 107.140 67.982  146.816 1.00 170.16 ? 317 SER A CA  1 
ATOM   1218  C C   . SER A 1 318 ? 108.182 66.969  146.308 1.00 154.36 ? 317 SER A C   1 
ATOM   1219  O O   . SER A 1 318 ? 107.937 66.241  145.321 1.00 159.74 ? 317 SER A O   1 
ATOM   1220  C CB  . SER A 1 318 ? 106.928 69.081  145.846 1.00 214.13 ? 317 SER A CB  1 
ATOM   1221  O OG  . SER A 1 318 ? 105.869 69.937  146.303 1.00 182.14 ? 317 SER A OG  1 
ATOM   1222  N N   . TRP A 1 319 ? 109.337 66.874  146.966 1.00 93.15  ? 318 TRP A N   1 
ATOM   1223  C CA  . TRP A 1 319 ? 110.285 65.843  146.570 1.00 113.52 ? 318 TRP A CA  1 
ATOM   1224  C C   . TRP A 1 319 ? 110.395 64.702  147.579 1.00 143.95 ? 318 TRP A C   1 
ATOM   1225  O O   . TRP A 1 319 ? 111.302 63.883  147.466 1.00 132.64 ? 318 TRP A O   1 
ATOM   1226  C CB  . TRP A 1 319 ? 111.646 66.514  146.393 1.00 142.63 ? 318 TRP A CB  1 
ATOM   1227  C CG  . TRP A 1 319 ? 111.577 67.466  145.257 1.00 118.27 ? 318 TRP A CG  1 
ATOM   1228  C CD1 . TRP A 1 319 ? 111.300 68.790  145.313 1.00 138.20 ? 318 TRP A CD1 1 
ATOM   1229  C CD2 . TRP A 1 319 ? 111.777 67.140  143.892 1.00 94.47  ? 318 TRP A CD2 1 
ATOM   1230  N NE1 . TRP A 1 319 ? 111.322 69.309  144.064 1.00 142.00 ? 318 TRP A NE1 1 
ATOM   1231  C CE2 . TRP A 1 319 ? 111.611 68.328  143.171 1.00 142.91 ? 318 TRP A CE2 1 
ATOM   1232  C CE3 . TRP A 1 319 ? 112.090 65.991  143.202 1.00 103.91 ? 318 TRP A CE3 1 
ATOM   1233  C CZ2 . TRP A 1 319 ? 111.734 68.403  141.790 1.00 146.89 ? 318 TRP A CZ2 1 
ATOM   1234  C CZ3 . TRP A 1 319 ? 112.213 66.062  141.834 1.00 136.92 ? 318 TRP A CZ3 1 
ATOM   1235  C CH2 . TRP A 1 319 ? 112.032 67.249  141.134 1.00 121.20 ? 318 TRP A CH2 1 
ATOM   1236  N N   . PHE A 1 320 ? 109.495 64.649  148.562 1.00 146.11 ? 319 PHE A N   1 
ATOM   1237  C CA  . PHE A 1 320 ? 109.619 63.764  149.706 1.00 163.56 ? 319 PHE A CA  1 
ATOM   1238  C C   . PHE A 1 320 ? 110.820 64.114  150.599 1.00 204.67 ? 319 PHE A C   1 
ATOM   1239  O O   . PHE A 1 320 ? 111.776 64.788  150.207 1.00 215.84 ? 319 PHE A O   1 
ATOM   1240  C CB  . PHE A 1 320 ? 109.683 62.312  149.236 1.00 155.31 ? 319 PHE A CB  1 
ATOM   1241  C CG  . PHE A 1 320 ? 108.591 61.829  148.305 1.00 153.86 ? 319 PHE A CG  1 
ATOM   1242  C CD1 . PHE A 1 320 ? 107.294 61.549  148.744 1.00 187.22 ? 319 PHE A CD1 1 
ATOM   1243  C CD2 . PHE A 1 320 ? 108.886 61.629  146.975 1.00 123.20 ? 319 PHE A CD2 1 
ATOM   1244  C CE1 . PHE A 1 320 ? 106.329 61.089  147.859 1.00 151.78 ? 319 PHE A CE1 1 
ATOM   1245  C CE2 . PHE A 1 320 ? 107.928 61.170  146.091 1.00 165.13 ? 319 PHE A CE2 1 
ATOM   1246  C CZ  . PHE A 1 320 ? 106.655 60.894  146.533 1.00 157.19 ? 319 PHE A CZ  1 
ATOM   1247  N N   . SER A 1 321 ? 110.765 63.629  151.845 1.00 240.34 ? 320 SER A N   1 
ATOM   1248  C CA  . SER A 1 321 ? 111.719 64.017  152.877 1.00 266.96 ? 320 SER A CA  1 
ATOM   1249  C C   . SER A 1 321 ? 113.009 63.183  152.840 1.00 287.09 ? 320 SER A C   1 
ATOM   1250  O O   . SER A 1 321 ? 113.966 63.526  153.531 1.00 302.61 ? 320 SER A O   1 
ATOM   1251  C CB  . SER A 1 321 ? 111.049 63.936  154.231 1.00 289.03 ? 320 SER A CB  1 
ATOM   1252  O OG  . SER A 1 321 ? 111.890 64.461  155.248 1.00 344.19 ? 320 SER A OG  1 
ATOM   1253  N N   . THR A 1 322 ? 113.048 62.095  152.042 1.00 274.19 ? 321 THR A N   1 
ATOM   1254  C CA  . THR A 1 322 ? 113.958 60.973  152.249 1.00 307.74 ? 321 THR A CA  1 
ATOM   1255  C C   . THR A 1 322 ? 114.422 60.396  150.909 1.00 264.34 ? 321 THR A C   1 
ATOM   1256  O O   . THR A 1 322 ? 113.708 60.500  149.918 1.00 212.05 ? 321 THR A O   1 
ATOM   1257  C CB  . THR A 1 322 ? 113.263 59.894  153.098 1.00 350.57 ? 321 THR A CB  1 
ATOM   1258  O OG1 . THR A 1 322 ? 112.704 60.479  154.277 1.00 355.97 ? 321 THR A OG1 1 
ATOM   1259  C CG2 . THR A 1 322 ? 114.179 58.769  153.537 1.00 404.23 ? 321 THR A CG2 1 
ATOM   1260  N N   . GLN A 1 323 ? 115.621 59.776  150.914 1.00 292.77 ? 322 GLN A N   1 
ATOM   1261  C CA  . GLN A 1 323 ? 116.181 58.921  149.859 1.00 298.94 ? 322 GLN A CA  1 
ATOM   1262  C C   . GLN A 1 323 ? 116.054 59.565  148.469 1.00 239.85 ? 322 GLN A C   1 
ATOM   1263  O O   . GLN A 1 323 ? 115.643 58.929  147.493 1.00 228.76 ? 322 GLN A O   1 
ATOM   1264  C CB  . GLN A 1 323 ? 115.615 57.490  149.942 1.00 335.89 ? 322 GLN A CB  1 
ATOM   1265  C CG  . GLN A 1 323 ? 114.105 57.306  149.742 1.00 363.07 ? 322 GLN A CG  1 
ATOM   1266  C CD  . GLN A 1 323 ? 113.673 55.853  149.728 1.00 376.57 ? 322 GLN A CD  1 
ATOM   1267  O OE1 . GLN A 1 323 ? 114.367 54.976  149.218 1.00 425.81 ? 322 GLN A OE1 1 
ATOM   1268  N NE2 . GLN A 1 323 ? 112.510 55.573  150.299 1.00 366.94 ? 322 GLN A NE2 1 
ATOM   1269  N N   . VAL A 1 324 ? 116.462 60.837  148.398 1.00 226.67 ? 323 VAL A N   1 
ATOM   1270  C CA  . VAL A 1 324 ? 116.219 61.727  147.268 1.00 272.33 ? 323 VAL A CA  1 
ATOM   1271  C C   . VAL A 1 324 ? 116.751 61.155  145.947 1.00 257.22 ? 323 VAL A C   1 
ATOM   1272  O O   . VAL A 1 324 ? 116.162 61.433  144.893 1.00 296.54 ? 323 VAL A O   1 
ATOM   1273  C CB  . VAL A 1 324 ? 116.811 63.123  147.570 1.00 309.19 ? 323 VAL A CB  1 
ATOM   1274  C CG1 . VAL A 1 324 ? 118.333 63.130  147.647 1.00 319.12 ? 323 VAL A CG1 1 
ATOM   1275  C CG2 . VAL A 1 324 ? 116.341 64.164  146.572 1.00 318.21 ? 323 VAL A CG2 1 
ATOM   1276  N N   . ASP A 1 325 ? 117.854 60.376  146.001 1.00 190.21 ? 324 ASP A N   1 
ATOM   1277  C CA  . ASP A 1 325 ? 118.465 59.813  144.803 1.00 256.52 ? 324 ASP A CA  1 
ATOM   1278  C C   . ASP A 1 325 ? 117.537 58.809  144.102 1.00 267.56 ? 324 ASP A C   1 
ATOM   1279  O O   . ASP A 1 325 ? 117.605 58.692  142.876 1.00 247.16 ? 324 ASP A O   1 
ATOM   1280  C CB  . ASP A 1 325 ? 119.846 59.214  145.106 1.00 325.47 ? 324 ASP A CB  1 
ATOM   1281  C CG  . ASP A 1 325 ? 119.904 58.177  146.218 1.00 407.05 ? 324 ASP A CG  1 
ATOM   1282  O OD1 . ASP A 1 325 ? 118.883 57.974  146.905 1.00 438.24 ? 324 ASP A OD1 1 
ATOM   1283  O OD2 . ASP A 1 325 ? 120.984 57.577  146.392 1.00 466.20 ? 324 ASP A OD2 1 
ATOM   1284  N N   . THR A 1 326 ? 116.687 58.088  144.860 1.00 261.57 ? 325 THR A N   1 
ATOM   1285  C CA  . THR A 1 326 ? 115.655 57.236  144.276 1.00 244.11 ? 325 THR A CA  1 
ATOM   1286  C C   . THR A 1 326 ? 114.607 58.093  143.566 1.00 209.98 ? 325 THR A C   1 
ATOM   1287  O O   . THR A 1 326 ? 114.131 57.706  142.505 1.00 188.09 ? 325 THR A O   1 
ATOM   1288  C CB  . THR A 1 326 ? 114.975 56.308  145.298 1.00 284.47 ? 325 THR A CB  1 
ATOM   1289  O OG1 . THR A 1 326 ? 114.188 57.061  146.228 1.00 204.35 ? 325 THR A OG1 1 
ATOM   1290  C CG2 . THR A 1 326 ? 115.969 55.437  146.044 1.00 317.20 ? 325 THR A CG2 1 
ATOM   1291  N N   . VAL A 1 327 ? 114.264 59.254  144.148 1.00 179.25 ? 326 VAL A N   1 
ATOM   1292  C CA  . VAL A 1 327 ? 113.297 60.176  143.559 1.00 153.57 ? 326 VAL A CA  1 
ATOM   1293  C C   . VAL A 1 327 ? 113.851 60.801  142.268 1.00 133.63 ? 326 VAL A C   1 
ATOM   1294  O O   . VAL A 1 327 ? 113.191 60.751  141.234 1.00 122.88 ? 326 VAL A O   1 
ATOM   1295  C CB  . VAL A 1 327 ? 112.846 61.250  144.553 1.00 143.18 ? 326 VAL A CB  1 
ATOM   1296  C CG1 . VAL A 1 327 ? 111.655 61.970  143.979 1.00 196.37 ? 326 VAL A CG1 1 
ATOM   1297  C CG2 . VAL A 1 327 ? 112.488 60.660  145.898 1.00 165.59 ? 326 VAL A CG2 1 
ATOM   1298  N N   . ALA A 1 328 ? 115.063 61.350  142.310 1.00 117.18 ? 327 ALA A N   1 
ATOM   1299  C CA  . ALA A 1 328 ? 115.788 61.701  141.093 1.00 148.35 ? 327 ALA A CA  1 
ATOM   1300  C C   . ALA A 1 328 ? 115.850 60.577  140.045 1.00 150.79 ? 327 ALA A C   1 
ATOM   1301  O O   . ALA A 1 328 ? 115.729 60.845  138.846 1.00 159.84 ? 327 ALA A O   1 
ATOM   1302  C CB  . ALA A 1 328 ? 117.203 62.112  141.448 1.00 197.03 ? 327 ALA A CB  1 
ATOM   1303  N N   . THR A 1 329 ? 116.063 59.325  140.477 1.00 154.28 ? 328 THR A N   1 
ATOM   1304  C CA  . THR A 1 329 ? 116.075 58.188  139.571 1.00 185.97 ? 328 THR A CA  1 
ATOM   1305  C C   . THR A 1 329 ? 114.710 58.036  138.894 1.00 177.47 ? 328 THR A C   1 
ATOM   1306  O O   . THR A 1 329 ? 114.678 57.783  137.686 1.00 179.58 ? 328 THR A O   1 
ATOM   1307  C CB  . THR A 1 329 ? 116.549 56.914  140.282 1.00 228.05 ? 328 THR A CB  1 
ATOM   1308  O OG1 . THR A 1 329 ? 117.881 57.181  140.726 1.00 251.63 ? 328 THR A OG1 1 
ATOM   1309  C CG2 . THR A 1 329 ? 116.542 55.678  139.406 1.00 262.14 ? 328 THR A CG2 1 
ATOM   1310  N N   . LYS A 1 330 ? 113.607 58.192  139.652 1.00 141.90 ? 329 LYS A N   1 
ATOM   1311  C CA  . LYS A 1 330 ? 112.274 58.148  139.063 1.00 159.61 ? 329 LYS A CA  1 
ATOM   1312  C C   . LYS A 1 330 ? 112.188 59.171  137.938 1.00 114.61 ? 329 LYS A C   1 
ATOM   1313  O O   . LYS A 1 330 ? 111.744 58.841  136.842 1.00 185.96 ? 329 LYS A O   1 
ATOM   1314  C CB  . LYS A 1 330 ? 111.135 58.388  140.063 1.00 203.76 ? 329 LYS A CB  1 
ATOM   1315  C CG  . LYS A 1 330 ? 110.920 57.254  141.062 1.00 249.84 ? 329 LYS A CG  1 
ATOM   1316  C CD  . LYS A 1 330 ? 109.775 57.522  142.010 1.00 273.76 ? 329 LYS A CD  1 
ATOM   1317  C CE  . LYS A 1 330 ? 109.635 56.494  143.107 1.00 273.13 ? 329 LYS A CE  1 
ATOM   1318  N NZ  . LYS A 1 330 ? 108.834 55.335  142.659 1.00 284.46 ? 329 LYS A NZ  1 
ATOM   1319  N N   . VAL A 1 331 ? 112.616 60.398  138.202 1.00 98.06  ? 330 VAL A N   1 
ATOM   1320  C CA  . VAL A 1 331 ? 112.556 61.448  137.191 1.00 118.89 ? 330 VAL A CA  1 
ATOM   1321  C C   . VAL A 1 331 ? 113.431 61.118  135.974 1.00 134.69 ? 330 VAL A C   1 
ATOM   1322  O O   . VAL A 1 331 ? 112.992 61.263  134.835 1.00 111.11 ? 330 VAL A O   1 
ATOM   1323  C CB  . VAL A 1 331 ? 112.939 62.804  137.792 1.00 121.96 ? 330 VAL A CB  1 
ATOM   1324  C CG1 . VAL A 1 331 ? 113.081 63.875  136.743 1.00 121.62 ? 330 VAL A CG1 1 
ATOM   1325  C CG2 . VAL A 1 331 ? 111.892 63.209  138.818 1.00 166.24 ? 330 VAL A CG2 1 
ATOM   1326  N N   . LYS A 1 332 ? 114.658 60.665  136.214 1.00 138.24 ? 331 LYS A N   1 
ATOM   1327  C CA  . LYS A 1 332 ? 115.560 60.377  135.123 1.00 160.88 ? 331 LYS A CA  1 
ATOM   1328  C C   . LYS A 1 332 ? 114.908 59.421  134.118 1.00 178.20 ? 331 LYS A C   1 
ATOM   1329  O O   . LYS A 1 332 ? 115.116 59.588  132.909 1.00 182.50 ? 331 LYS A O   1 
ATOM   1330  C CB  . LYS A 1 332 ? 116.850 59.791  135.704 1.00 221.63 ? 331 LYS A CB  1 
ATOM   1331  C CG  . LYS A 1 332 ? 117.882 59.337  134.674 1.00 230.41 ? 331 LYS A CG  1 
ATOM   1332  C CD  . LYS A 1 332 ? 119.141 58.823  135.308 1.00 285.36 ? 331 LYS A CD  1 
ATOM   1333  C CE  . LYS A 1 332 ? 120.250 58.560  134.315 1.00 369.31 ? 331 LYS A CE  1 
ATOM   1334  N NZ  . LYS A 1 332 ? 121.577 58.628  134.974 1.00 448.35 ? 331 LYS A NZ  1 
ATOM   1335  N N   . ASP A 1 333 ? 114.166 58.415  134.627 1.00 163.50 ? 332 ASP A N   1 
ATOM   1336  C CA  . ASP A 1 333 ? 113.432 57.467  133.798 1.00 204.33 ? 332 ASP A CA  1 
ATOM   1337  C C   . ASP A 1 333 ? 112.223 58.136  133.146 1.00 150.02 ? 332 ASP A C   1 
ATOM   1338  O O   . ASP A 1 333 ? 111.954 57.892  131.970 1.00 149.28 ? 332 ASP A O   1 
ATOM   1339  C CB  . ASP A 1 333 ? 113.022 56.233  134.610 1.00 245.56 ? 332 ASP A CB  1 
ATOM   1340  C CG  . ASP A 1 333 ? 114.174 55.341  135.058 1.00 328.73 ? 332 ASP A CG  1 
ATOM   1341  O OD1 . ASP A 1 333 ? 115.324 55.560  134.604 1.00 369.87 ? 332 ASP A OD1 1 
ATOM   1342  O OD2 . ASP A 1 333 ? 113.913 54.424  135.862 1.00 393.53 ? 332 ASP A OD2 1 
ATOM   1343  N N   . ALA A 1 334 ? 111.514 58.965  133.918 1.00 122.82 ? 333 ALA A N   1 
ATOM   1344  C CA  . ALA A 1 334 ? 110.256 59.562  133.490 1.00 122.76 ? 333 ALA A CA  1 
ATOM   1345  C C   . ALA A 1 334 ? 110.449 60.455  132.280 1.00 111.15 ? 333 ALA A C   1 
ATOM   1346  O O   . ALA A 1 334 ? 109.586 60.443  131.386 1.00 88.46  ? 333 ALA A O   1 
ATOM   1347  C CB  . ALA A 1 334 ? 109.625 60.375  134.589 1.00 124.55 ? 333 ALA A CB  1 
ATOM   1348  N N   . LEU A 1 335 ? 111.564 61.200  132.258 1.00 94.76  ? 334 LEU A N   1 
ATOM   1349  C CA  . LEU A 1 335 ? 111.723 62.193  131.212 1.00 114.90 ? 334 LEU A CA  1 
ATOM   1350  C C   . LEU A 1 335 ? 111.807 61.500  129.853 1.00 160.87 ? 334 LEU A C   1 
ATOM   1351  O O   . LEU A 1 335 ? 111.206 61.946  128.873 1.00 101.55 ? 334 LEU A O   1 
ATOM   1352  C CB  . LEU A 1 335 ? 112.975 63.006  131.457 1.00 113.66 ? 334 LEU A CB  1 
ATOM   1353  C CG  . LEU A 1 335 ? 112.957 63.791  132.746 1.00 126.03 ? 334 LEU A CG  1 
ATOM   1354  C CD1 . LEU A 1 335 ? 114.376 64.270  133.126 1.00 183.02 ? 334 LEU A CD1 1 
ATOM   1355  C CD2 . LEU A 1 335 ? 111.983 64.946  132.632 1.00 105.30 ? 334 LEU A CD2 1 
ATOM   1356  N N   . GLU A 1 336 ? 112.547 60.388  129.805 1.00 168.91 ? 335 GLU A N   1 
ATOM   1357  C CA  . GLU A 1 336 ? 112.690 59.615  128.584 1.00 176.75 ? 335 GLU A CA  1 
ATOM   1358  C C   . GLU A 1 336 ? 111.323 59.093  128.114 1.00 158.28 ? 335 GLU A C   1 
ATOM   1359  O O   . GLU A 1 336 ? 111.004 59.198  126.926 1.00 136.63 ? 335 GLU A O   1 
ATOM   1360  C CB  . GLU A 1 336 ? 113.698 58.500  128.851 1.00 225.21 ? 335 GLU A CB  1 
ATOM   1361  C CG  . GLU A 1 336 ? 113.971 57.629  127.637 1.00 317.36 ? 335 GLU A CG  1 
ATOM   1362  C CD  . GLU A 1 336 ? 114.997 56.526  127.841 1.00 396.78 ? 335 GLU A CD  1 
ATOM   1363  O OE1 . GLU A 1 336 ? 115.542 56.408  128.959 1.00 438.12 ? 335 GLU A OE1 1 
ATOM   1364  O OE2 . GLU A 1 336 ? 115.248 55.781  126.874 1.00 444.15 ? 335 GLU A OE2 1 
ATOM   1365  N N   . PHE A 1 337 ? 110.530 58.515  129.032 1.00 122.97 ? 336 PHE A N   1 
ATOM   1366  C CA  . PHE A 1 337 ? 109.237 57.948  128.682 1.00 125.35 ? 336 PHE A CA  1 
ATOM   1367  C C   . PHE A 1 337 ? 108.333 59.013  128.065 1.00 109.66 ? 336 PHE A C   1 
ATOM   1368  O O   . PHE A 1 337 ? 107.757 58.806  126.980 1.00 119.65 ? 336 PHE A O   1 
ATOM   1369  C CB  . PHE A 1 337 ? 108.543 57.294  129.881 1.00 120.02 ? 336 PHE A CB  1 
ATOM   1370  C CG  . PHE A 1 337 ? 107.122 56.862  129.607 1.00 139.96 ? 336 PHE A CG  1 
ATOM   1371  C CD1 . PHE A 1 337 ? 106.844 55.659  128.978 1.00 196.53 ? 336 PHE A CD1 1 
ATOM   1372  C CD2 . PHE A 1 337 ? 106.050 57.671  129.961 1.00 128.26 ? 336 PHE A CD2 1 
ATOM   1373  C CE1 . PHE A 1 337 ? 105.526 55.286  128.729 1.00 250.29 ? 336 PHE A CE1 1 
ATOM   1374  C CE2 . PHE A 1 337 ? 104.740 57.306  129.715 1.00 152.23 ? 336 PHE A CE2 1 
ATOM   1375  C CZ  . PHE A 1 337 ? 104.477 56.107  129.104 1.00 218.17 ? 336 PHE A CZ  1 
ATOM   1376  N N   . TRP A 1 338 ? 108.193 60.136  128.769 1.00 82.27  ? 337 TRP A N   1 
ATOM   1377  C CA  . TRP A 1 338 ? 107.196 61.086  128.323 1.00 84.02  ? 337 TRP A CA  1 
ATOM   1378  C C   . TRP A 1 338 ? 107.679 61.831  127.092 1.00 108.45 ? 337 TRP A C   1 
ATOM   1379  O O   . TRP A 1 338 ? 106.831 62.243  126.306 1.00 146.24 ? 337 TRP A O   1 
ATOM   1380  C CB  . TRP A 1 338 ? 106.854 62.063  129.408 1.00 74.85  ? 337 TRP A CB  1 
ATOM   1381  C CG  . TRP A 1 338 ? 106.097 61.463  130.543 1.00 90.46  ? 337 TRP A CG  1 
ATOM   1382  C CD1 . TRP A 1 338 ? 106.455 61.114  131.828 1.00 79.34  ? 337 TRP A CD1 1 
ATOM   1383  C CD2 . TRP A 1 338 ? 104.704 61.214  130.413 1.00 95.23  ? 337 TRP A CD2 1 
ATOM   1384  N NE1 . TRP A 1 338 ? 105.352 60.649  132.493 1.00 78.51  ? 337 TRP A NE1 1 
ATOM   1385  C CE2 . TRP A 1 338 ? 104.272 60.701  131.649 1.00 81.47  ? 337 TRP A CE2 1 
ATOM   1386  C CE3 . TRP A 1 338 ? 103.814 61.384  129.359 1.00 111.20 ? 337 TRP A CE3 1 
ATOM   1387  C CZ2 . TRP A 1 338 ? 102.958 60.352  131.841 1.00 109.52 ? 337 TRP A CZ2 1 
ATOM   1388  C CZ3 . TRP A 1 338 ? 102.502 61.057  129.565 1.00 117.07 ? 337 TRP A CZ3 1 
ATOM   1389  C CH2 . TRP A 1 338 ? 102.090 60.550  130.783 1.00 168.36 ? 337 TRP A CH2 1 
ATOM   1390  N N   . LEU A 1 339 ? 109.002 61.984  126.895 1.00 75.58  ? 338 LEU A N   1 
ATOM   1391  C CA  . LEU A 1 339 ? 109.455 62.523  125.623 1.00 106.73 ? 338 LEU A CA  1 
ATOM   1392  C C   . LEU A 1 339 ? 109.068 61.588  124.474 1.00 160.37 ? 338 LEU A C   1 
ATOM   1393  O O   . LEU A 1 339 ? 108.621 62.054  123.423 1.00 129.50 ? 338 LEU A O   1 
ATOM   1394  C CB  . LEU A 1 339 ? 110.965 62.684  125.702 1.00 110.28 ? 338 LEU A CB  1 
ATOM   1395  C CG  . LEU A 1 339 ? 111.408 63.922  126.443 1.00 124.39 ? 338 LEU A CG  1 
ATOM   1396  C CD1 . LEU A 1 339 ? 112.893 63.845  126.807 1.00 181.41 ? 338 LEU A CD1 1 
ATOM   1397  C CD2 . LEU A 1 339 ? 111.119 65.126  125.570 1.00 121.72 ? 338 LEU A CD2 1 
ATOM   1398  N N   . GLN A 1 340 ? 109.242 60.267  124.684 1.00 151.17 ? 339 GLN A N   1 
ATOM   1399  C CA  . GLN A 1 340 ? 108.839 59.274  123.702 1.00 171.74 ? 339 GLN A CA  1 
ATOM   1400  C C   . GLN A 1 340 ? 107.337 59.374  123.410 1.00 165.77 ? 339 GLN A C   1 
ATOM   1401  O O   . GLN A 1 340 ? 106.925 59.129  122.266 1.00 202.57 ? 339 GLN A O   1 
ATOM   1402  C CB  . GLN A 1 340 ? 109.251 57.871  124.169 1.00 196.36 ? 339 GLN A CB  1 
ATOM   1403  C CG  . GLN A 1 340 ? 110.744 57.579  124.024 1.00 232.13 ? 339 GLN A CG  1 
ATOM   1404  C CD  . GLN A 1 340 ? 111.256 57.467  122.604 1.00 306.69 ? 339 GLN A CD  1 
ATOM   1405  O OE1 . GLN A 1 340 ? 112.425 57.731  122.338 1.00 335.74 ? 339 GLN A OE1 1 
ATOM   1406  N NE2 . GLN A 1 340 ? 110.400 57.085  121.667 1.00 352.56 ? 339 GLN A NE2 1 
ATOM   1407  N N   . ALA A 1 341 ? 106.541 59.708  124.435 1.00 168.18 ? 340 ALA A N   1 
ATOM   1408  C CA  . ALA A 1 341 ? 105.109 59.934  124.290 1.00 172.90 ? 340 ALA A CA  1 
ATOM   1409  C C   . ALA A 1 341 ? 104.781 61.217  123.503 1.00 133.96 ? 340 ALA A C   1 
ATOM   1410  O O   . ALA A 1 341 ? 103.710 61.287  122.890 1.00 115.08 ? 340 ALA A O   1 
ATOM   1411  C CB  . ALA A 1 341 ? 104.477 59.935  125.669 1.00 198.80 ? 340 ALA A CB  1 
ATOM   1412  N N   . GLY A 1 342 ? 105.671 62.224  123.534 1.00 141.95 ? 341 GLY A N   1 
ATOM   1413  C CA  . GLY A 1 342 ? 105.640 63.365  122.621 1.00 181.53 ? 341 GLY A CA  1 
ATOM   1414  C C   . GLY A 1 342 ? 105.439 64.742  123.266 1.00 150.75 ? 341 GLY A C   1 
ATOM   1415  O O   . GLY A 1 342 ? 105.149 65.709  122.552 1.00 147.80 ? 341 GLY A O   1 
ATOM   1416  N N   . VAL A 1 343 ? 105.603 64.833  124.591 1.00 113.66 ? 342 VAL A N   1 
ATOM   1417  C CA  . VAL A 1 343 ? 105.414 66.074  125.329 1.00 89.61  ? 342 VAL A CA  1 
ATOM   1418  C C   . VAL A 1 343 ? 106.552 67.016  125.007 1.00 77.92  ? 342 VAL A C   1 
ATOM   1419  O O   . VAL A 1 343 ? 107.618 66.498  124.754 1.00 102.69 ? 342 VAL A O   1 
ATOM   1420  C CB  . VAL A 1 343 ? 105.426 65.850  126.850 1.00 88.67  ? 342 VAL A CB  1 
ATOM   1421  C CG1 . VAL A 1 343 ? 104.442 64.801  127.296 1.00 104.23 ? 342 VAL A CG1 1 
ATOM   1422  C CG2 . VAL A 1 343 ? 106.816 65.495  127.348 1.00 76.72  ? 342 VAL A CG2 1 
ATOM   1423  N N   . ASP A 1 344 ? 106.319 68.340  125.084 1.00 82.06  ? 343 ASP A N   1 
ATOM   1424  C CA  . ASP A 1 344 ? 107.254 69.357  124.623 1.00 83.24  ? 343 ASP A CA  1 
ATOM   1425  C C   . ASP A 1 344 ? 108.216 69.841  125.700 1.00 76.12  ? 343 ASP A C   1 
ATOM   1426  O O   . ASP A 1 344 ? 109.126 70.619  125.362 1.00 106.76 ? 343 ASP A O   1 
ATOM   1427  C CB  . ASP A 1 344 ? 106.550 70.525  123.993 1.00 103.33 ? 343 ASP A CB  1 
ATOM   1428  C CG  . ASP A 1 344 ? 105.742 70.025  122.802 1.00 190.02 ? 343 ASP A CG  1 
ATOM   1429  O OD1 . ASP A 1 344 ? 106.344 69.551  121.814 1.00 257.80 ? 343 ASP A OD1 1 
ATOM   1430  O OD2 . ASP A 1 344 ? 104.505 70.125  122.867 1.00 216.01 ? 343 ASP A OD2 1 
ATOM   1431  N N   . GLY A 1 345 ? 108.118 69.286  126.905 1.00 63.20  ? 344 GLY A N   1 
ATOM   1432  C CA  . GLY A 1 345 ? 109.181 69.419  127.883 1.00 60.51  ? 344 GLY A CA  1 
ATOM   1433  C C   . GLY A 1 345 ? 108.598 69.251  129.275 1.00 57.42  ? 344 GLY A C   1 
ATOM   1434  O O   . GLY A 1 345 ? 107.542 68.707  129.426 1.00 80.05  ? 344 GLY A O   1 
ATOM   1435  N N   . PHE A 1 346 ? 109.283 69.724  130.287 1.00 52.41  ? 345 PHE A N   1 
ATOM   1436  C CA  . PHE A 1 346 ? 108.940 69.422  131.650 1.00 59.37  ? 345 PHE A CA  1 
ATOM   1437  C C   . PHE A 1 346 ? 109.075 70.626  132.564 1.00 61.10  ? 345 PHE A C   1 
ATOM   1438  O O   . PHE A 1 346 ? 109.943 71.461  132.443 1.00 118.26 ? 345 PHE A O   1 
ATOM   1439  C CB  . PHE A 1 346 ? 109.880 68.324  132.174 1.00 83.87  ? 345 PHE A CB  1 
ATOM   1440  C CG  . PHE A 1 346 ? 109.657 67.108  131.321 1.00 73.54  ? 345 PHE A CG  1 
ATOM   1441  C CD1 . PHE A 1 346 ? 108.560 66.309  131.433 1.00 84.02  ? 345 PHE A CD1 1 
ATOM   1442  C CD2 . PHE A 1 346 ? 110.512 66.832  130.343 1.00 74.00  ? 345 PHE A CD2 1 
ATOM   1443  C CE1 . PHE A 1 346 ? 108.369 65.241  130.599 1.00 101.88 ? 345 PHE A CE1 1 
ATOM   1444  C CE2 . PHE A 1 346 ? 110.345 65.764  129.522 1.00 101.70 ? 345 PHE A CE2 1 
ATOM   1445  C CZ  . PHE A 1 346 ? 109.274 64.970  129.641 1.00 135.12 ? 345 PHE A CZ  1 
ATOM   1446  N N   . GLN A 1 347 ? 108.183 70.707  133.516 1.00 60.56  ? 346 GLN A N   1 
ATOM   1447  C CA  . GLN A 1 347 ? 108.304 71.687  134.559 1.00 52.58  ? 346 GLN A CA  1 
ATOM   1448  C C   . GLN A 1 347 ? 108.629 70.819  135.746 1.00 48.33  ? 346 GLN A C   1 
ATOM   1449  O O   . GLN A 1 347 ? 108.026 69.775  135.890 1.00 61.67  ? 346 GLN A O   1 
ATOM   1450  C CB  . GLN A 1 347 ? 107.050 72.575  134.700 1.00 60.72  ? 346 GLN A CB  1 
ATOM   1451  C CG  . GLN A 1 347 ? 106.913 73.217  136.040 1.00 62.71  ? 346 GLN A CG  1 
ATOM   1452  C CD  . GLN A 1 347 ? 105.866 74.260  136.084 1.00 72.97  ? 346 GLN A CD  1 
ATOM   1453  O OE1 . GLN A 1 347 ? 106.079 75.431  135.723 1.00 61.51  ? 346 GLN A OE1 1 
ATOM   1454  N NE2 . GLN A 1 347 ? 104.731 73.797  136.602 1.00 93.27  ? 346 GLN A NE2 1 
ATOM   1455  N N   . VAL A 1 348 ? 109.574 71.268  136.585 1.00 61.61  ? 347 VAL A N   1 
ATOM   1456  C CA  . VAL A 1 348 ? 109.683 70.801  137.967 1.00 59.36  ? 347 VAL A CA  1 
ATOM   1457  C C   . VAL A 1 348 ? 109.597 71.985  138.915 1.00 62.06  ? 347 VAL A C   1 
ATOM   1458  O O   . VAL A 1 348 ? 110.022 73.086  138.589 1.00 70.57  ? 347 VAL A O   1 
ATOM   1459  C CB  . VAL A 1 348 ? 110.965 70.006  138.111 1.00 57.82  ? 347 VAL A CB  1 
ATOM   1460  C CG1 . VAL A 1 348 ? 110.957 68.806  137.176 1.00 79.08  ? 347 VAL A CG1 1 
ATOM   1461  C CG2 . VAL A 1 348 ? 112.151 70.868  137.780 1.00 75.85  ? 347 VAL A CG2 1 
ATOM   1462  N N   . ARG A 1 349 ? 109.051 71.735  140.090 1.00 67.14  ? 348 ARG A N   1 
ATOM   1463  C CA  . ARG A 1 349 ? 108.854 72.755  141.103 1.00 81.65  ? 348 ARG A CA  1 
ATOM   1464  C C   . ARG A 1 349 ? 109.626 72.513  142.401 1.00 74.69  ? 348 ARG A C   1 
ATOM   1465  O O   . ARG A 1 349 ? 110.223 71.478  142.650 1.00 110.44 ? 348 ARG A O   1 
ATOM   1466  C CB  . ARG A 1 349 ? 107.354 72.774  141.326 1.00 71.28  ? 348 ARG A CB  1 
ATOM   1467  C CG  . ARG A 1 349 ? 106.713 73.351  140.097 1.00 87.00  ? 348 ARG A CG  1 
ATOM   1468  C CD  . ARG A 1 349 ? 105.358 73.972  140.458 1.00 99.14  ? 348 ARG A CD  1 
ATOM   1469  N NE  . ARG A 1 349 ? 104.350 72.992  140.193 1.00 111.55 ? 348 ARG A NE  1 
ATOM   1470  C CZ  . ARG A 1 349 ? 103.672 72.287  141.106 1.00 144.15 ? 348 ARG A CZ  1 
ATOM   1471  N NH1 . ARG A 1 349 ? 102.839 71.395  140.625 1.00 169.16 ? 348 ARG A NH1 1 
ATOM   1472  N NH2 . ARG A 1 349 ? 103.783 72.423  142.432 1.00 130.27 ? 348 ARG A NH2 1 
ATOM   1473  N N   . ASP A 1 350 ? 109.592 73.516  143.218 1.00 64.21  ? 349 ASP A N   1 
ATOM   1474  C CA  . ASP A 1 350 ? 110.104 73.413  144.552 1.00 108.62 ? 349 ASP A CA  1 
ATOM   1475  C C   . ASP A 1 350 ? 111.581 72.988  144.620 1.00 94.50  ? 349 ASP A C   1 
ATOM   1476  O O   . ASP A 1 350 ? 111.940 72.420  145.647 1.00 154.76 ? 349 ASP A O   1 
ATOM   1477  C CB  . ASP A 1 350 ? 109.134 72.565  145.375 1.00 108.89 ? 349 ASP A CB  1 
ATOM   1478  C CG  . ASP A 1 350 ? 107.721 73.094  145.485 1.00 171.70 ? 349 ASP A CG  1 
ATOM   1479  O OD1 . ASP A 1 350 ? 107.434 74.228  145.055 1.00 157.82 ? 349 ASP A OD1 1 
ATOM   1480  O OD2 . ASP A 1 350 ? 106.899 72.349  146.035 1.00 260.35 ? 349 ASP A OD2 1 
ATOM   1481  N N   . ILE A 1 351 ? 112.419 73.317  143.641 1.00 68.64  ? 350 ILE A N   1 
ATOM   1482  C CA  . ILE A 1 351 ? 113.787 72.847  143.667 1.00 102.35 ? 350 ILE A CA  1 
ATOM   1483  C C   . ILE A 1 351 ? 114.580 73.324  144.907 1.00 141.99 ? 350 ILE A C   1 
ATOM   1484  O O   . ILE A 1 351 ? 115.682 72.812  145.134 1.00 141.53 ? 350 ILE A O   1 
ATOM   1485  C CB  . ILE A 1 351 ? 114.503 73.234  142.354 1.00 88.28  ? 350 ILE A CB  1 
ATOM   1486  C CG1 . ILE A 1 351 ? 114.494 74.734  142.168 1.00 100.36 ? 350 ILE A CG1 1 
ATOM   1487  C CG2 . ILE A 1 351 ? 113.905 72.588  141.152 1.00 73.47  ? 350 ILE A CG2 1 
ATOM   1488  C CD1 . ILE A 1 351 ? 115.367 75.138  141.050 1.00 164.24 ? 350 ILE A CD1 1 
ATOM   1489  N N   . GLU A 1 352 ? 114.094 74.284  145.712 1.00 117.78 ? 351 GLU A N   1 
ATOM   1490  C CA  . GLU A 1 352 ? 114.734 74.526  146.998 1.00 165.27 ? 351 GLU A CA  1 
ATOM   1491  C C   . GLU A 1 352 ? 114.554 73.376  148.003 1.00 161.86 ? 351 GLU A C   1 
ATOM   1492  O O   . GLU A 1 352 ? 115.371 73.263  148.930 1.00 218.65 ? 351 GLU A O   1 
ATOM   1493  C CB  . GLU A 1 352 ? 114.224 75.819  147.631 1.00 222.64 ? 351 GLU A CB  1 
ATOM   1494  C CG  . GLU A 1 352 ? 112.758 75.807  148.064 1.00 192.67 ? 351 GLU A CG  1 
ATOM   1495  C CD  . GLU A 1 352 ? 111.713 75.870  146.975 1.00 194.63 ? 351 GLU A CD  1 
ATOM   1496  O OE1 . GLU A 1 352 ? 112.078 76.218  145.815 1.00 268.56 ? 351 GLU A OE1 1 
ATOM   1497  O OE2 . GLU A 1 352 ? 110.545 75.587  147.297 1.00 183.95 ? 351 GLU A OE2 1 
ATOM   1498  N N   . ASN A 1 353 ? 113.510 72.544  147.849 1.00 116.86 ? 352 ASN A N   1 
ATOM   1499  C CA  . ASN A 1 353 ? 113.338 71.367  148.705 1.00 118.38 ? 352 ASN A CA  1 
ATOM   1500  C C   . ASN A 1 353 ? 113.980 70.090  148.118 1.00 142.78 ? 352 ASN A C   1 
ATOM   1501  O O   . ASN A 1 353 ? 113.805 68.997  148.658 1.00 148.93 ? 352 ASN A O   1 
ATOM   1502  C CB  . ASN A 1 353 ? 111.867 71.051  148.927 1.00 127.46 ? 352 ASN A CB  1 
ATOM   1503  C CG  . ASN A 1 353 ? 111.084 71.932  149.863 1.00 158.49 ? 352 ASN A CG  1 
ATOM   1504  O OD1 . ASN A 1 353 ? 109.885 71.711  150.048 1.00 264.56 ? 352 ASN A OD1 1 
ATOM   1505  N ND2 . ASN A 1 353 ? 111.734 72.901  150.464 1.00 190.76 ? 352 ASN A ND2 1 
ATOM   1506  N N   . LEU A 1 354 ? 114.735 70.211  147.016 1.00 125.48 ? 353 LEU A N   1 
ATOM   1507  C CA  . LEU A 1 354 ? 115.493 69.119  146.450 1.00 120.84 ? 353 LEU A CA  1 
ATOM   1508  C C   . LEU A 1 354 ? 116.977 69.284  146.840 1.00 166.21 ? 353 LEU A C   1 
ATOM   1509  O O   . LEU A 1 354 ? 117.590 70.330  146.584 1.00 186.46 ? 353 LEU A O   1 
ATOM   1510  C CB  . LEU A 1 354 ? 115.264 69.194  144.942 1.00 103.95 ? 353 LEU A CB  1 
ATOM   1511  C CG  . LEU A 1 354 ? 116.028 68.204  144.052 1.00 111.70 ? 353 LEU A CG  1 
ATOM   1512  C CD1 . LEU A 1 354 ? 115.529 66.809  144.208 1.00 125.14 ? 353 LEU A CD1 1 
ATOM   1513  C CD2 . LEU A 1 354 ? 115.925 68.557  142.592 1.00 142.96 ? 353 LEU A CD2 1 
ATOM   1514  N N   . LYS A 1 355 ? 117.570 68.249  147.453 1.00 155.79 ? 354 LYS A N   1 
ATOM   1515  C CA  . LYS A 1 355 ? 119.001 68.248  147.723 1.00 203.47 ? 354 LYS A CA  1 
ATOM   1516  C C   . LYS A 1 355 ? 119.799 68.181  146.413 1.00 164.51 ? 354 LYS A C   1 
ATOM   1517  O O   . LYS A 1 355 ? 119.396 67.482  145.495 1.00 143.51 ? 354 LYS A O   1 
ATOM   1518  C CB  . LYS A 1 355 ? 119.362 67.067  148.633 1.00 290.26 ? 354 LYS A CB  1 
ATOM   1519  C CG  . LYS A 1 355 ? 120.813 67.025  149.104 1.00 372.18 ? 354 LYS A CG  1 
ATOM   1520  C CD  . LYS A 1 355 ? 121.078 66.088  150.281 1.00 432.37 ? 354 LYS A CD  1 
ATOM   1521  C CE  . LYS A 1 355 ? 121.003 64.611  149.945 1.00 480.55 ? 354 LYS A CE  1 
ATOM   1522  N NZ  . LYS A 1 355 ? 122.134 64.156  149.099 1.00 507.73 ? 354 LYS A NZ  1 
ATOM   1523  N N   . ASP A 1 356 ? 120.930 68.904  146.336 1.00 181.39 ? 355 ASP A N   1 
ATOM   1524  C CA  . ASP A 1 356 ? 121.849 68.873  145.198 1.00 237.94 ? 355 ASP A CA  1 
ATOM   1525  C C   . ASP A 1 356 ? 121.140 69.295  143.902 1.00 216.95 ? 355 ASP A C   1 
ATOM   1526  O O   . ASP A 1 356 ? 121.385 68.736  142.829 1.00 155.39 ? 355 ASP A O   1 
ATOM   1527  C CB  . ASP A 1 356 ? 122.519 67.495  145.079 1.00 293.61 ? 355 ASP A CB  1 
ATOM   1528  C CG  . ASP A 1 356 ? 123.775 67.434  144.217 1.00 366.38 ? 355 ASP A CG  1 
ATOM   1529  O OD1 . ASP A 1 356 ? 124.276 68.504  143.805 1.00 386.66 ? 355 ASP A OD1 1 
ATOM   1530  O OD2 . ASP A 1 356 ? 124.247 66.303  143.959 1.00 423.65 ? 355 ASP A OD2 1 
ATOM   1531  N N   . ALA A 1 357 ? 120.273 70.313  144.018 1.00 200.09 ? 356 ALA A N   1 
ATOM   1532  C CA  . ALA A 1 357 ? 119.315 70.668  142.982 1.00 160.32 ? 356 ALA A CA  1 
ATOM   1533  C C   . ALA A 1 357 ? 119.991 70.950  141.647 1.00 146.78 ? 356 ALA A C   1 
ATOM   1534  O O   . ALA A 1 357 ? 119.560 70.403  140.623 1.00 143.18 ? 356 ALA A O   1 
ATOM   1535  C CB  . ALA A 1 357 ? 118.553 71.880  143.403 1.00 178.03 ? 356 ALA A CB  1 
ATOM   1536  N N   . SER A 1 358 ? 121.030 71.807  141.664 1.00 124.02 ? 357 SER A N   1 
ATOM   1537  C CA  . SER A 1 358 ? 121.717 72.194  140.429 1.00 160.52 ? 357 SER A CA  1 
ATOM   1538  C C   . SER A 1 358 ? 122.225 70.985  139.595 1.00 145.24 ? 357 SER A C   1 
ATOM   1539  O O   . SER A 1 358 ? 122.200 71.025  138.355 1.00 169.44 ? 357 SER A O   1 
ATOM   1540  C CB  . SER A 1 358 ? 122.807 73.175  140.750 1.00 172.87 ? 357 SER A CB  1 
ATOM   1541  O OG  . SER A 1 358 ? 123.737 72.607  141.655 1.00 249.90 ? 357 SER A OG  1 
ATOM   1542  N N   . SER A 1 359 ? 122.667 69.910  140.267 1.00 175.90 ? 358 SER A N   1 
ATOM   1543  C CA  . SER A 1 359 ? 123.205 68.722  139.615 1.00 189.44 ? 358 SER A CA  1 
ATOM   1544  C C   . SER A 1 359 ? 122.106 67.931  138.921 1.00 172.18 ? 358 SER A C   1 
ATOM   1545  O O   . SER A 1 359 ? 122.307 67.466  137.794 1.00 197.71 ? 358 SER A O   1 
ATOM   1546  C CB  . SER A 1 359 ? 123.933 67.842  140.592 1.00 231.61 ? 358 SER A CB  1 
ATOM   1547  O OG  . SER A 1 359 ? 124.964 68.578  141.237 1.00 316.80 ? 358 SER A OG  1 
ATOM   1548  N N   . PHE A 1 360 ? 120.962 67.781  139.601 1.00 147.60 ? 359 PHE A N   1 
ATOM   1549  C CA  . PHE A 1 360 ? 119.828 67.074  139.009 1.00 155.63 ? 359 PHE A CA  1 
ATOM   1550  C C   . PHE A 1 360 ? 119.252 67.870  137.847 1.00 128.24 ? 359 PHE A C   1 
ATOM   1551  O O   . PHE A 1 360 ? 118.945 67.241  136.843 1.00 138.68 ? 359 PHE A O   1 
ATOM   1552  C CB  . PHE A 1 360 ? 118.766 66.714  140.044 1.00 134.85 ? 359 PHE A CB  1 
ATOM   1553  C CG  . PHE A 1 360 ? 119.231 65.733  141.096 1.00 133.23 ? 359 PHE A CG  1 
ATOM   1554  C CD1 . PHE A 1 360 ? 119.889 64.571  140.731 1.00 129.27 ? 359 PHE A CD1 1 
ATOM   1555  C CD2 . PHE A 1 360 ? 118.993 65.962  142.456 1.00 182.04 ? 359 PHE A CD2 1 
ATOM   1556  C CE1 . PHE A 1 360 ? 120.318 63.665  141.686 1.00 210.33 ? 359 PHE A CE1 1 
ATOM   1557  C CE2 . PHE A 1 360 ? 119.433 65.057  143.411 1.00 218.35 ? 359 PHE A CE2 1 
ATOM   1558  C CZ  . PHE A 1 360 ? 120.089 63.908  143.024 1.00 246.99 ? 359 PHE A CZ  1 
ATOM   1559  N N   . LEU A 1 361 ? 119.170 69.212  137.956 1.00 114.89 ? 360 LEU A N   1 
ATOM   1560  C CA  . LEU A 1 361 ? 118.756 70.030  136.800 1.00 117.82 ? 360 LEU A CA  1 
ATOM   1561  C C   . LEU A 1 361 ? 119.720 69.828  135.639 1.00 109.16 ? 360 LEU A C   1 
ATOM   1562  O O   . LEU A 1 361 ? 119.259 69.680  134.515 1.00 101.89 ? 360 LEU A O   1 
ATOM   1563  C CB  . LEU A 1 361 ? 118.599 71.531  137.068 1.00 76.26  ? 360 LEU A CB  1 
ATOM   1564  C CG  . LEU A 1 361 ? 117.516 71.875  138.110 1.00 101.61 ? 360 LEU A CG  1 
ATOM   1565  C CD1 . LEU A 1 361 ? 117.432 73.371  138.291 1.00 123.43 ? 360 LEU A CD1 1 
ATOM   1566  C CD2 . LEU A 1 361 ? 116.134 71.336  137.814 1.00 82.15  ? 360 LEU A CD2 1 
ATOM   1567  N N   . ALA A 1 362 ? 121.017 69.777  135.903 1.00 111.60 ? 361 ALA A N   1 
ATOM   1568  C CA  . ALA A 1 362 ? 121.982 69.587  134.832 1.00 145.17 ? 361 ALA A CA  1 
ATOM   1569  C C   . ALA A 1 362 ? 121.789 68.254  134.119 1.00 145.22 ? 361 ALA A C   1 
ATOM   1570  O O   . ALA A 1 362 ? 121.882 68.212  132.883 1.00 139.11 ? 361 ALA A O   1 
ATOM   1571  C CB  . ALA A 1 362 ? 123.391 69.747  135.374 1.00 203.13 ? 361 ALA A CB  1 
ATOM   1572  N N   . GLU A 1 363 ? 121.534 67.190  134.894 1.00 140.12 ? 362 GLU A N   1 
ATOM   1573  C CA  . GLU A 1 363 ? 121.328 65.873  134.316 1.00 167.40 ? 362 GLU A CA  1 
ATOM   1574  C C   . GLU A 1 363 ? 120.054 65.874  133.449 1.00 147.54 ? 362 GLU A C   1 
ATOM   1575  O O   . GLU A 1 363 ? 120.080 65.439  132.295 1.00 118.83 ? 362 GLU A O   1 
ATOM   1576  C CB  . GLU A 1 363 ? 121.294 64.844  135.448 1.00 222.26 ? 362 GLU A CB  1 
ATOM   1577  C CG  . GLU A 1 363 ? 121.119 63.410  134.970 1.00 297.45 ? 362 GLU A CG  1 
ATOM   1578  C CD  . GLU A 1 363 ? 121.087 62.342  136.055 1.00 374.94 ? 362 GLU A CD  1 
ATOM   1579  O OE1 . GLU A 1 363 ? 120.423 62.560  137.092 1.00 383.88 ? 362 GLU A OE1 1 
ATOM   1580  O OE2 . GLU A 1 363 ? 121.720 61.285  135.857 1.00 445.32 ? 362 GLU A OE2 1 
ATOM   1581  N N   . TRP A 1 364 ? 118.938 66.354  134.023 1.00 110.82 ? 363 TRP A N   1 
ATOM   1582  C CA  . TRP A 1 364 ? 117.642 66.365  133.366 1.00 95.62  ? 363 TRP A CA  1 
ATOM   1583  C C   . TRP A 1 364 ? 117.607 67.270  132.136 1.00 102.90 ? 363 TRP A C   1 
ATOM   1584  O O   . TRP A 1 364 ? 116.942 66.957  131.134 1.00 106.17 ? 363 TRP A O   1 
ATOM   1585  C CB  . TRP A 1 364 ? 116.568 66.825  134.354 1.00 94.46  ? 363 TRP A CB  1 
ATOM   1586  C CG  . TRP A 1 364 ? 116.461 65.933  135.549 1.00 102.28 ? 363 TRP A CG  1 
ATOM   1587  C CD1 . TRP A 1 364 ? 116.899 64.659  135.740 1.00 107.70 ? 363 TRP A CD1 1 
ATOM   1588  C CD2 . TRP A 1 364 ? 115.863 66.349  136.769 1.00 104.70 ? 363 TRP A CD2 1 
ATOM   1589  N NE1 . TRP A 1 364 ? 116.603 64.253  137.009 1.00 118.27 ? 363 TRP A NE1 1 
ATOM   1590  C CE2 . TRP A 1 364 ? 115.973 65.270  137.661 1.00 107.10 ? 363 TRP A CE2 1 
ATOM   1591  C CE3 . TRP A 1 364 ? 115.250 67.526  137.172 1.00 100.68 ? 363 TRP A CE3 1 
ATOM   1592  C CZ2 . TRP A 1 364 ? 115.484 65.338  138.959 1.00 122.26 ? 363 TRP A CZ2 1 
ATOM   1593  C CZ3 . TRP A 1 364 ? 114.768 67.588  138.463 1.00 135.72 ? 363 TRP A CZ3 1 
ATOM   1594  C CH2 . TRP A 1 364 ? 114.904 66.518  139.353 1.00 127.76 ? 363 TRP A CH2 1 
ATOM   1595  N N   . GLN A 1 365 ? 118.301 68.392  132.230 1.00 81.83  ? 364 GLN A N   1 
ATOM   1596  C CA  . GLN A 1 365 ? 118.432 69.272  131.094 1.00 99.12  ? 364 GLN A CA  1 
ATOM   1597  C C   . GLN A 1 365 ? 119.200 68.554  129.990 1.00 136.08 ? 364 GLN A C   1 
ATOM   1598  O O   . GLN A 1 365 ? 118.754 68.613  128.845 1.00 127.62 ? 364 GLN A O   1 
ATOM   1599  C CB  . GLN A 1 365 ? 119.122 70.538  131.601 1.00 123.85 ? 364 GLN A CB  1 
ATOM   1600  C CG  . GLN A 1 365 ? 119.482 71.594  130.584 1.00 142.50 ? 364 GLN A CG  1 
ATOM   1601  C CD  . GLN A 1 365 ? 118.319 72.352  130.009 1.00 148.48 ? 364 GLN A CD  1 
ATOM   1602  O OE1 . GLN A 1 365 ? 117.161 71.983  130.138 1.00 166.05 ? 364 GLN A OE1 1 
ATOM   1603  N NE2 . GLN A 1 365 ? 118.642 73.426  129.317 1.00 218.02 ? 364 GLN A NE2 1 
ATOM   1604  N N   . ASN A 1 366 ? 120.343 67.909  130.331 1.00 144.81 ? 365 ASN A N   1 
ATOM   1605  C CA  . ASN A 1 366 ? 121.100 67.139  129.357 1.00 144.22 ? 365 ASN A CA  1 
ATOM   1606  C C   . ASN A 1 366 ? 120.208 66.090  128.702 1.00 165.47 ? 365 ASN A C   1 
ATOM   1607  O O   . ASN A 1 366 ? 120.255 65.942  127.486 1.00 186.70 ? 365 ASN A O   1 
ATOM   1608  C CB  . ASN A 1 366 ? 122.334 66.468  129.951 1.00 192.10 ? 365 ASN A CB  1 
ATOM   1609  C CG  . ASN A 1 366 ? 123.612 67.149  129.521 1.00 302.94 ? 365 ASN A CG  1 
ATOM   1610  O OD1 . ASN A 1 366 ? 123.803 68.323  129.830 1.00 359.05 ? 365 ASN A OD1 1 
ATOM   1611  N ND2 . ASN A 1 366 ? 124.464 66.415  128.813 1.00 336.44 ? 365 ASN A ND2 1 
ATOM   1612  N N   . ILE A 1 367 ? 119.399 65.370  129.497 1.00 145.48 ? 366 ILE A N   1 
ATOM   1613  C CA  . ILE A 1 367 ? 118.521 64.335  128.958 1.00 117.38 ? 366 ILE A CA  1 
ATOM   1614  C C   . ILE A 1 367 ? 117.526 64.922  127.972 1.00 110.99 ? 366 ILE A C   1 
ATOM   1615  O O   . ILE A 1 367 ? 117.330 64.328  126.910 1.00 94.43  ? 366 ILE A O   1 
ATOM   1616  C CB  . ILE A 1 367 ? 117.852 63.559  130.085 1.00 126.72 ? 366 ILE A CB  1 
ATOM   1617  C CG1 . ILE A 1 367 ? 118.920 62.689  130.775 1.00 203.98 ? 366 ILE A CG1 1 
ATOM   1618  C CG2 . ILE A 1 367 ? 116.666 62.741  129.561 1.00 159.40 ? 366 ILE A CG2 1 
ATOM   1619  C CD1 . ILE A 1 367 ? 118.585 62.247  132.178 1.00 285.98 ? 366 ILE A CD1 1 
ATOM   1620  N N   . THR A 1 368 ? 116.965 66.090  128.317 1.00 142.06 ? 367 THR A N   1 
ATOM   1621  C CA  . THR A 1 368 ? 115.969 66.737  127.474 1.00 146.48 ? 367 THR A CA  1 
ATOM   1622  C C   . THR A 1 368 ? 116.593 67.260  126.172 1.00 138.89 ? 367 THR A C   1 
ATOM   1623  O O   . THR A 1 368 ? 116.163 66.854  125.102 1.00 182.70 ? 367 THR A O   1 
ATOM   1624  C CB  . THR A 1 368 ? 115.241 67.872  128.200 1.00 120.97 ? 367 THR A CB  1 
ATOM   1625  O OG1 . THR A 1 368 ? 114.776 67.291  129.424 1.00 86.62  ? 367 THR A OG1 1 
ATOM   1626  C CG2 . THR A 1 368 ? 114.190 68.510  127.297 1.00 94.74  ? 367 THR A CG2 1 
ATOM   1627  N N   . LYS A 1 369 ? 117.593 68.143  126.249 1.00 136.62 ? 368 LYS A N   1 
ATOM   1628  C CA  . LYS A 1 369 ? 118.219 68.699  125.059 1.00 165.60 ? 368 LYS A CA  1 
ATOM   1629  C C   . LYS A 1 369 ? 118.878 67.603  124.211 1.00 205.53 ? 368 LYS A C   1 
ATOM   1630  O O   . LYS A 1 369 ? 118.937 67.716  122.983 1.00 198.33 ? 368 LYS A O   1 
ATOM   1631  C CB  . LYS A 1 369 ? 119.255 69.745  125.477 1.00 218.05 ? 368 LYS A CB  1 
ATOM   1632  C CG  . LYS A 1 369 ? 118.662 71.063  125.942 1.00 242.34 ? 368 LYS A CG  1 
ATOM   1633  C CD  . LYS A 1 369 ? 118.215 71.887  124.778 1.00 291.93 ? 368 LYS A CD  1 
ATOM   1634  C CE  . LYS A 1 369 ? 117.820 73.303  125.129 1.00 309.80 ? 368 LYS A CE  1 
ATOM   1635  N NZ  . LYS A 1 369 ? 117.799 74.156  123.913 1.00 341.82 ? 368 LYS A NZ  1 
ATOM   1636  N N   . GLY A 1 370 ? 119.382 66.551  124.877 1.00 191.50 ? 369 GLY A N   1 
ATOM   1637  C CA  . GLY A 1 370 ? 119.942 65.382  124.223 1.00 211.18 ? 369 GLY A CA  1 
ATOM   1638  C C   . GLY A 1 370 ? 118.922 64.604  123.407 1.00 189.03 ? 369 GLY A C   1 
ATOM   1639  O O   . GLY A 1 370 ? 119.307 63.898  122.468 1.00 294.95 ? 369 GLY A O   1 
ATOM   1640  N N   . PHE A 1 371 ? 117.642 64.722  123.766 1.00 121.69 ? 370 PHE A N   1 
ATOM   1641  C CA  . PHE A 1 371 ? 116.593 64.160  122.922 1.00 153.18 ? 370 PHE A CA  1 
ATOM   1642  C C   . PHE A 1 371 ? 116.314 65.010  121.685 1.00 132.54 ? 370 PHE A C   1 
ATOM   1643  O O   . PHE A 1 371 ? 116.371 64.515  120.566 1.00 184.57 ? 370 PHE A O   1 
ATOM   1644  C CB  . PHE A 1 371 ? 115.309 64.011  123.709 1.00 169.66 ? 370 PHE A CB  1 
ATOM   1645  C CG  . PHE A 1 371 ? 114.314 63.103  123.064 1.00 132.68 ? 370 PHE A CG  1 
ATOM   1646  C CD1 . PHE A 1 371 ? 113.441 63.614  122.109 1.00 103.19 ? 370 PHE A CD1 1 
ATOM   1647  C CD2 . PHE A 1 371 ? 114.275 61.758  123.443 1.00 143.53 ? 370 PHE A CD2 1 
ATOM   1648  C CE1 . PHE A 1 371 ? 112.509 62.765  121.524 1.00 186.73 ? 370 PHE A CE1 1 
ATOM   1649  C CE2 . PHE A 1 371 ? 113.346 60.918  122.857 1.00 214.38 ? 370 PHE A CE2 1 
ATOM   1650  C CZ  . PHE A 1 371 ? 112.469 61.418  121.896 1.00 262.02 ? 370 PHE A CZ  1 
ATOM   1651  N N   . SER A 1 372 ? 116.017 66.284  121.896 1.00 144.95 ? 371 SER A N   1 
ATOM   1652  C CA  . SER A 1 372 ? 115.792 67.212  120.805 1.00 182.02 ? 371 SER A CA  1 
ATOM   1653  C C   . SER A 1 372 ? 116.024 68.632  121.314 1.00 183.40 ? 371 SER A C   1 
ATOM   1654  O O   . SER A 1 372 ? 115.882 68.921  122.493 1.00 190.93 ? 371 SER A O   1 
ATOM   1655  C CB  . SER A 1 372 ? 114.415 67.029  120.162 1.00 187.93 ? 371 SER A CB  1 
ATOM   1656  O OG  . SER A 1 372 ? 114.135 68.004  119.146 1.00 172.74 ? 371 SER A OG  1 
ATOM   1657  N N   . GLU A 1 373 ? 116.394 69.517  120.393 1.00 167.67 ? 372 GLU A N   1 
ATOM   1658  C CA  . GLU A 1 373 ? 116.805 70.866  120.743 1.00 144.47 ? 372 GLU A CA  1 
ATOM   1659  C C   . GLU A 1 373 ? 115.562 71.706  121.045 1.00 113.10 ? 372 GLU A C   1 
ATOM   1660  O O   . GLU A 1 373 ? 115.687 72.698  121.759 1.00 196.12 ? 372 GLU A O   1 
ATOM   1661  C CB  . GLU A 1 373 ? 117.714 71.457  119.654 1.00 205.13 ? 372 GLU A CB  1 
ATOM   1662  C CG  . GLU A 1 373 ? 117.154 71.425  118.226 1.00 272.26 ? 372 GLU A CG  1 
ATOM   1663  C CD  . GLU A 1 373 ? 118.038 72.087  117.182 1.00 391.85 ? 372 GLU A CD  1 
ATOM   1664  O OE1 . GLU A 1 373 ? 118.422 73.257  117.399 1.00 495.14 ? 372 GLU A OE1 1 
ATOM   1665  O OE2 . GLU A 1 373 ? 118.337 71.438  116.156 1.00 451.33 ? 372 GLU A OE2 1 
ATOM   1666  N N   . ASP A 1 374 ? 114.375 71.325  120.534 1.00 112.43 ? 373 ASP A N   1 
ATOM   1667  C CA  . ASP A 1 374 ? 113.124 72.062  120.730 1.00 124.04 ? 373 ASP A CA  1 
ATOM   1668  C C   . ASP A 1 374 ? 112.262 71.440  121.843 1.00 118.19 ? 373 ASP A C   1 
ATOM   1669  O O   . ASP A 1 374 ? 111.031 71.344  121.704 1.00 123.93 ? 373 ASP A O   1 
ATOM   1670  C CB  . ASP A 1 374 ? 112.370 72.241  119.397 1.00 175.32 ? 373 ASP A CB  1 
ATOM   1671  C CG  . ASP A 1 374 ? 112.860 73.440  118.580 1.00 261.93 ? 373 ASP A CG  1 
ATOM   1672  O OD1 . ASP A 1 374 ? 114.109 73.605  118.459 1.00 279.90 ? 373 ASP A OD1 1 
ATOM   1673  O OD2 . ASP A 1 374 ? 112.004 74.216  118.063 1.00 276.56 ? 373 ASP A OD2 1 
ATOM   1674  N N   . ARG A 1 375 ? 112.900 71.059  122.966 1.00 95.93  ? 374 ARG A N   1 
ATOM   1675  C CA  . ARG A 1 375 ? 112.206 70.745  124.200 1.00 99.81  ? 374 ARG A CA  1 
ATOM   1676  C C   . ARG A 1 375 ? 112.846 71.495  125.350 1.00 120.17 ? 374 ARG A C   1 
ATOM   1677  O O   . ARG A 1 375 ? 114.080 71.673  125.342 1.00 142.88 ? 374 ARG A O   1 
ATOM   1678  C CB  . ARG A 1 375 ? 112.283 69.240  124.474 1.00 91.40  ? 374 ARG A CB  1 
ATOM   1679  C CG  . ARG A 1 375 ? 111.211 68.456  123.754 1.00 102.27 ? 374 ARG A CG  1 
ATOM   1680  C CD  . ARG A 1 375 ? 111.639 67.813  122.494 1.00 114.98 ? 374 ARG A CD  1 
ATOM   1681  N NE  . ARG A 1 375 ? 110.524 67.721  121.539 1.00 145.42 ? 374 ARG A NE  1 
ATOM   1682  C CZ  . ARG A 1 375 ? 109.733 66.674  121.384 1.00 193.65 ? 374 ARG A CZ  1 
ATOM   1683  N NH1 . ARG A 1 375 ? 108.872 66.638  120.383 1.00 262.37 ? 374 ARG A NH1 1 
ATOM   1684  N NH2 . ARG A 1 375 ? 109.811 65.653  122.224 1.00 140.25 ? 374 ARG A NH2 1 
ATOM   1685  N N   . LEU A 1 376 ? 112.009 71.894  126.345 1.00 82.72  ? 375 LEU A N   1 
ATOM   1686  C CA  . LEU A 1 376 ? 112.609 72.629  127.475 1.00 99.91  ? 375 LEU A CA  1 
ATOM   1687  C C   . LEU A 1 376 ? 112.252 72.055  128.822 1.00 63.06  ? 375 LEU A C   1 
ATOM   1688  O O   . LEU A 1 376 ? 111.288 71.340  128.947 1.00 65.92  ? 375 LEU A O   1 
ATOM   1689  C CB  . LEU A 1 376 ? 112.298 74.125  127.561 1.00 90.66  ? 375 LEU A CB  1 
ATOM   1690  C CG  . LEU A 1 376 ? 110.926 74.482  128.059 1.00 64.99  ? 375 LEU A CG  1 
ATOM   1691  C CD1 . LEU A 1 376 ? 110.674 75.962  128.026 1.00 77.90  ? 375 LEU A CD1 1 
ATOM   1692  C CD2 . LEU A 1 376 ? 109.967 73.911  127.091 1.00 107.60 ? 375 LEU A CD2 1 
ATOM   1693  N N   . LEU A 1 377 ? 113.112 72.428  129.763 1.00 59.33  ? 376 LEU A N   1 
ATOM   1694  C CA  . LEU A 1 377 ? 112.893 72.162  131.158 1.00 69.75  ? 376 LEU A CA  1 
ATOM   1695  C C   . LEU A 1 377 ? 112.722 73.554  131.826 1.00 60.22  ? 376 LEU A C   1 
ATOM   1696  O O   . LEU A 1 377 ? 113.627 74.335  131.900 1.00 79.75  ? 376 LEU A O   1 
ATOM   1697  C CB  . LEU A 1 377 ? 113.984 71.185  131.668 1.00 53.76  ? 376 LEU A CB  1 
ATOM   1698  C CG  . LEU A 1 377 ? 114.090 71.094  133.193 1.00 82.45  ? 376 LEU A CG  1 
ATOM   1699  C CD1 . LEU A 1 377 ? 112.939 70.280  133.801 1.00 151.29 ? 376 LEU A CD1 1 
ATOM   1700  C CD2 . LEU A 1 377 ? 115.387 70.425  133.595 1.00 119.42 ? 376 LEU A CD2 1 
ATOM   1701  N N   . ILE A 1 378 ? 111.526 73.841  132.342 1.00 70.76  ? 377 ILE A N   1 
ATOM   1702  C CA  . ILE A 1 378 ? 111.198 74.905  133.270 1.00 55.31  ? 377 ILE A CA  1 
ATOM   1703  C C   . ILE A 1 378 ? 111.385 74.432  134.715 1.00 63.32  ? 377 ILE A C   1 
ATOM   1704  O O   . ILE A 1 378 ? 110.576 73.781  135.306 1.00 88.60  ? 377 ILE A O   1 
ATOM   1705  C CB  . ILE A 1 378 ? 109.740 75.236  133.037 1.00 60.10  ? 377 ILE A CB  1 
ATOM   1706  C CG1 . ILE A 1 378 ? 109.542 75.718  131.620 1.00 85.41  ? 377 ILE A CG1 1 
ATOM   1707  C CG2 . ILE A 1 378 ? 109.293 76.290  133.978 1.00 102.85 ? 377 ILE A CG2 1 
ATOM   1708  C CD1 . ILE A 1 378 ? 108.120 75.962  131.273 1.00 105.22 ? 377 ILE A CD1 1 
ATOM   1709  N N   . ALA A 1 379 ? 112.454 74.731  135.383 1.00 65.26  ? 378 ALA A N   1 
ATOM   1710  C CA  . ALA A 1 379 ? 112.480 74.623  136.828 1.00 53.33  ? 378 ALA A CA  1 
ATOM   1711  C C   . ALA A 1 379 ? 111.803 75.784  137.510 1.00 45.31  ? 378 ALA A C   1 
ATOM   1712  O O   . ALA A 1 379 ? 111.551 76.821  136.929 1.00 50.88  ? 378 ALA A O   1 
ATOM   1713  C CB  . ALA A 1 379 ? 113.875 74.716  137.269 1.00 103.53 ? 378 ALA A CB  1 
ATOM   1714  N N   . GLY A 1 380 ? 111.488 75.620  138.786 1.00 63.60  ? 379 GLY A N   1 
ATOM   1715  C CA  . GLY A 1 380 ? 110.747 76.649  139.521 1.00 74.50  ? 379 GLY A CA  1 
ATOM   1716  C C   . GLY A 1 380 ? 111.087 76.575  140.982 1.00 78.80  ? 379 GLY A C   1 
ATOM   1717  O O   . GLY A 1 380 ? 111.220 75.471  141.504 1.00 120.79 ? 379 GLY A O   1 
ATOM   1718  N N   . THR A 1 381 ? 111.236 77.725  141.613 1.00 84.90  ? 380 THR A N   1 
ATOM   1719  C CA  . THR A 1 381 ? 111.646 77.789  143.006 1.00 85.78  ? 380 THR A CA  1 
ATOM   1720  C C   . THR A 1 381 ? 110.767 78.804  143.768 1.00 81.74  ? 380 THR A C   1 
ATOM   1721  O O   . THR A 1 381 ? 110.251 79.747  143.217 1.00 90.55  ? 380 THR A O   1 
ATOM   1722  C CB  . THR A 1 381 ? 113.117 78.167  143.150 1.00 81.12  ? 380 THR A CB  1 
ATOM   1723  O OG1 . THR A 1 381 ? 113.319 78.270  144.555 1.00 103.65 ? 380 THR A OG1 1 
ATOM   1724  C CG2 . THR A 1 381 ? 113.450 79.494  142.486 1.00 98.13  ? 380 THR A CG2 1 
ATOM   1725  N N   . ASN A 1 382 ? 110.601 78.601  145.073 1.00 96.33  ? 381 ASN A N   1 
ATOM   1726  C CA  . ASN A 1 382 ? 109.883 79.524  145.939 1.00 90.67  ? 381 ASN A CA  1 
ATOM   1727  C C   . ASN A 1 382 ? 110.802 80.703  146.241 1.00 91.54  ? 381 ASN A C   1 
ATOM   1728  O O   . ASN A 1 382 ? 110.314 81.709  146.782 1.00 106.03 ? 381 ASN A O   1 
ATOM   1729  C CB  . ASN A 1 382 ? 109.356 78.834  147.204 1.00 116.19 ? 381 ASN A CB  1 
ATOM   1730  C CG  . ASN A 1 382 ? 110.412 78.713  148.286 1.00 191.02 ? 381 ASN A CG  1 
ATOM   1731  O OD1 . ASN A 1 382 ? 111.615 78.769  148.006 1.00 150.72 ? 381 ASN A OD1 1 
ATOM   1732  N ND2 . ASN A 1 382 ? 109.953 78.551  149.519 1.00 270.55 ? 381 ASN A ND2 1 
ATOM   1733  N N   . SER A 1 383 ? 112.106 80.590  145.880 1.00 81.37  ? 382 SER A N   1 
ATOM   1734  C CA  . SER A 1 383 ? 113.093 81.648  146.100 1.00 114.57 ? 382 SER A CA  1 
ATOM   1735  C C   . SER A 1 383 ? 112.773 83.041  145.527 1.00 106.30 ? 382 SER A C   1 
ATOM   1736  O O   . SER A 1 383 ? 112.150 83.167  144.481 1.00 114.24 ? 382 SER A O   1 
ATOM   1737  C CB  . SER A 1 383 ? 114.396 81.260  145.559 1.00 121.85 ? 382 SER A CB  1 
ATOM   1738  O OG  . SER A 1 383 ? 115.340 82.194  146.037 1.00 155.71 ? 382 SER A OG  1 
ATOM   1739  N N   . SER A 1 384 ? 113.214 84.075  146.262 1.00 90.39  ? 383 SER A N   1 
ATOM   1740  C CA  . SER A 1 384 ? 113.209 85.448  145.815 1.00 102.97 ? 383 SER A CA  1 
ATOM   1741  C C   . SER A 1 384 ? 114.571 86.108  146.015 1.00 106.89 ? 383 SER A C   1 
ATOM   1742  O O   . SER A 1 384 ? 114.677 87.342  145.963 1.00 110.83 ? 383 SER A O   1 
ATOM   1743  C CB  . SER A 1 384 ? 112.108 86.204  146.528 1.00 134.88 ? 383 SER A CB  1 
ATOM   1744  O OG  . SER A 1 384 ? 112.388 86.515  147.885 1.00 137.33 ? 383 SER A OG  1 
ATOM   1745  N N   . ASP A 1 385 ? 115.617 85.298  146.232 1.00 128.57 ? 384 ASP A N   1 
ATOM   1746  C CA  . ASP A 1 385 ? 116.959 85.807  146.473 1.00 157.03 ? 384 ASP A CA  1 
ATOM   1747  C C   . ASP A 1 385 ? 117.692 85.843  145.147 1.00 120.57 ? 384 ASP A C   1 
ATOM   1748  O O   . ASP A 1 385 ? 117.824 84.809  144.464 1.00 156.43 ? 384 ASP A O   1 
ATOM   1749  C CB  . ASP A 1 385 ? 117.754 84.916  147.425 1.00 233.52 ? 384 ASP A CB  1 
ATOM   1750  C CG  . ASP A 1 385 ? 119.253 85.194  147.407 1.00 293.47 ? 384 ASP A CG  1 
ATOM   1751  O OD1 . ASP A 1 385 ? 119.635 86.351  147.133 1.00 317.17 ? 384 ASP A OD1 1 
ATOM   1752  O OD2 . ASP A 1 385 ? 120.042 84.250  147.633 1.00 355.91 ? 384 ASP A OD2 1 
ATOM   1753  N N   . LEU A 1 386 ? 118.194 87.018  144.766 1.00 97.12  ? 385 LEU A N   1 
ATOM   1754  C CA  . LEU A 1 386 ? 118.781 87.088  143.429 1.00 112.92 ? 385 LEU A CA  1 
ATOM   1755  C C   . LEU A 1 386 ? 119.960 86.126  143.256 1.00 108.36 ? 385 LEU A C   1 
ATOM   1756  O O   . LEU A 1 386 ? 120.228 85.578  142.180 1.00 115.84 ? 385 LEU A O   1 
ATOM   1757  C CB  . LEU A 1 386 ? 119.243 88.514  143.175 1.00 104.62 ? 385 LEU A CB  1 
ATOM   1758  C CG  . LEU A 1 386 ? 119.953 88.697  141.846 1.00 88.84  ? 385 LEU A CG  1 
ATOM   1759  C CD1 . LEU A 1 386 ? 119.136 88.101  140.723 1.00 87.04  ? 385 LEU A CD1 1 
ATOM   1760  C CD2 . LEU A 1 386 ? 120.184 90.183  141.576 1.00 160.33 ? 385 LEU A CD2 1 
ATOM   1761  N N   . GLN A 1 387 ? 120.694 85.936  144.349 1.00 136.16 ? 386 GLN A N   1 
ATOM   1762  C CA  . GLN A 1 387 ? 121.945 85.203  144.293 1.00 165.12 ? 386 GLN A CA  1 
ATOM   1763  C C   . GLN A 1 387 ? 121.664 83.709  144.208 1.00 152.42 ? 386 GLN A C   1 
ATOM   1764  O O   . GLN A 1 387 ? 122.309 83.025  143.410 1.00 165.55 ? 386 GLN A O   1 
ATOM   1765  C CB  . GLN A 1 387 ? 122.830 85.671  145.452 1.00 176.77 ? 386 GLN A CB  1 
ATOM   1766  C CG  . GLN A 1 387 ? 123.260 87.140  145.272 1.00 153.73 ? 386 GLN A CG  1 
ATOM   1767  C CD  . GLN A 1 387 ? 124.037 87.391  143.987 1.00 216.71 ? 386 GLN A CD  1 
ATOM   1768  O OE1 . GLN A 1 387 ? 124.655 86.475  143.421 1.00 208.27 ? 386 GLN A OE1 1 
ATOM   1769  N NE2 . GLN A 1 387 ? 124.021 88.641  143.524 1.00 219.41 ? 386 GLN A NE2 1 
ATOM   1770  N N   . GLN A 1 388 ? 120.705 83.219  145.000 1.00 121.97 ? 387 GLN A N   1 
ATOM   1771  C CA  . GLN A 1 388 ? 120.321 81.815  144.921 1.00 157.16 ? 387 GLN A CA  1 
ATOM   1772  C C   . GLN A 1 388 ? 119.862 81.485  143.491 1.00 135.68 ? 387 GLN A C   1 
ATOM   1773  O O   . GLN A 1 388 ? 120.276 80.484  142.876 1.00 137.21 ? 387 GLN A O   1 
ATOM   1774  C CB  . GLN A 1 388 ? 119.280 81.522  146.000 1.00 147.41 ? 387 GLN A CB  1 
ATOM   1775  C CG  . GLN A 1 388 ? 118.944 80.052  146.155 1.00 202.40 ? 387 GLN A CG  1 
ATOM   1776  C CD  . GLN A 1 388 ? 117.838 79.837  147.171 1.00 288.82 ? 387 GLN A CD  1 
ATOM   1777  O OE1 . GLN A 1 388 ? 117.119 80.761  147.567 1.00 262.40 ? 387 GLN A OE1 1 
ATOM   1778  N NE2 . GLN A 1 388 ? 117.676 78.594  147.598 1.00 357.78 ? 387 GLN A NE2 1 
ATOM   1779  N N   . ILE A 1 389 ? 119.017 82.342  142.942 1.00 106.28 ? 388 ILE A N   1 
ATOM   1780  C CA  . ILE A 1 389 ? 118.551 82.165  141.578 1.00 98.19  ? 388 ILE A CA  1 
ATOM   1781  C C   . ILE A 1 389 ? 119.737 82.141  140.603 1.00 91.52  ? 388 ILE A C   1 
ATOM   1782  O O   . ILE A 1 389 ? 119.809 81.236  139.762 1.00 130.88 ? 388 ILE A O   1 
ATOM   1783  C CB  . ILE A 1 389 ? 117.491 83.243  141.251 1.00 89.41  ? 388 ILE A CB  1 
ATOM   1784  C CG1 . ILE A 1 389 ? 116.186 82.929  141.967 1.00 109.33 ? 388 ILE A CG1 1 
ATOM   1785  C CG2 . ILE A 1 389 ? 117.264 83.367  139.778 1.00 104.89 ? 388 ILE A CG2 1 
ATOM   1786  C CD1 . ILE A 1 389 ? 115.304 84.140  142.167 1.00 114.58 ? 388 ILE A CD1 1 
ATOM   1787  N N   . LEU A 1 390 ? 120.635 83.122  140.680 1.00 99.27  ? 389 LEU A N   1 
ATOM   1788  C CA  . LEU A 1 390 ? 121.751 83.164  139.756 1.00 120.74 ? 389 LEU A CA  1 
ATOM   1789  C C   . LEU A 1 390 ? 122.627 81.916  139.905 1.00 147.15 ? 389 LEU A C   1 
ATOM   1790  O O   . LEU A 1 390 ? 123.283 81.556  138.926 1.00 165.79 ? 389 LEU A O   1 
ATOM   1791  C CB  . LEU A 1 390 ? 122.557 84.437  139.998 1.00 144.53 ? 389 LEU A CB  1 
ATOM   1792  C CG  . LEU A 1 390 ? 121.961 85.678  139.344 1.00 161.09 ? 389 LEU A CG  1 
ATOM   1793  C CD1 . LEU A 1 390 ? 122.422 86.937  140.037 1.00 196.44 ? 389 LEU A CD1 1 
ATOM   1794  C CD2 . LEU A 1 390 ? 122.360 85.746  137.866 1.00 159.81 ? 389 LEU A CD2 1 
ATOM   1795  N N   . SER A 1 391 ? 122.646 81.276  141.096 1.00 128.85 ? 390 SER A N   1 
ATOM   1796  C CA  . SER A 1 391 ? 123.446 80.073  141.305 1.00 170.90 ? 390 SER A CA  1 
ATOM   1797  C C   . SER A 1 391 ? 122.839 78.869  140.575 1.00 154.53 ? 390 SER A C   1 
ATOM   1798  O O   . SER A 1 391 ? 123.609 78.093  139.989 1.00 217.69 ? 390 SER A O   1 
ATOM   1799  C CB  . SER A 1 391 ? 123.688 79.804  142.782 1.00 205.12 ? 390 SER A CB  1 
ATOM   1800  O OG  . SER A 1 391 ? 122.550 79.262  143.432 1.00 206.39 ? 390 SER A OG  1 
ATOM   1801  N N   . LEU A 1 392 ? 121.494 78.708  140.601 1.00 110.61 ? 391 LEU A N   1 
ATOM   1802  C CA  . LEU A 1 392 ? 120.815 77.610  139.869 1.00 124.07 ? 391 LEU A CA  1 
ATOM   1803  C C   . LEU A 1 392 ? 120.995 77.787  138.366 1.00 124.01 ? 391 LEU A C   1 
ATOM   1804  O O   . LEU A 1 392 ? 121.099 76.810  137.639 1.00 122.64 ? 391 LEU A O   1 
ATOM   1805  C CB  . LEU A 1 392 ? 119.305 77.497  140.166 1.00 84.17  ? 391 LEU A CB  1 
ATOM   1806  C CG  . LEU A 1 392 ? 118.900 76.915  141.521 1.00 122.72 ? 391 LEU A CG  1 
ATOM   1807  C CD1 . LEU A 1 392 ? 120.026 76.854  142.555 1.00 217.74 ? 391 LEU A CD1 1 
ATOM   1808  C CD2 . LEU A 1 392 ? 117.755 77.713  142.184 1.00 153.58 ? 391 LEU A CD2 1 
ATOM   1809  N N   . LEU A 1 393 ? 121.028 79.044  137.931 1.00 130.14 ? 392 LEU A N   1 
ATOM   1810  C CA  . LEU A 1 393 ? 121.197 79.412  136.542 1.00 117.56 ? 392 LEU A CA  1 
ATOM   1811  C C   . LEU A 1 393 ? 122.669 79.535  136.125 1.00 153.18 ? 392 LEU A C   1 
ATOM   1812  O O   . LEU A 1 393 ? 122.950 80.064  135.018 1.00 274.54 ? 392 LEU A O   1 
ATOM   1813  C CB  . LEU A 1 393 ? 120.568 80.800  136.413 1.00 129.26 ? 392 LEU A CB  1 
ATOM   1814  C CG  . LEU A 1 393 ? 119.109 80.920  136.109 1.00 130.29 ? 392 LEU A CG  1 
ATOM   1815  C CD1 . LEU A 1 393 ? 118.661 82.330  136.521 1.00 160.56 ? 392 LEU A CD1 1 
ATOM   1816  C CD2 . LEU A 1 393 ? 118.894 80.685  134.611 1.00 232.49 ? 392 LEU A CD2 1 
ATOM   1817  N N   . GLU A 1 394 ? 123.637 79.126  136.963 1.00 150.22 ? 393 GLU A N   1 
ATOM   1818  C CA  . GLU A 1 394 ? 125.032 79.343  136.603 1.00 221.80 ? 393 GLU A CA  1 
ATOM   1819  C C   . GLU A 1 394 ? 125.497 78.208  135.694 1.00 230.70 ? 393 GLU A C   1 
ATOM   1820  O O   . GLU A 1 394 ? 126.035 78.458  134.615 1.00 229.37 ? 393 GLU A O   1 
ATOM   1821  C CB  . GLU A 1 394 ? 125.905 79.458  137.849 1.00 290.96 ? 393 GLU A CB  1 
ATOM   1822  C CG  . GLU A 1 394 ? 127.345 79.805  137.527 1.00 341.42 ? 393 GLU A CG  1 
ATOM   1823  C CD  . GLU A 1 394 ? 128.088 80.470  138.674 1.00 429.13 ? 393 GLU A CD  1 
ATOM   1824  O OE1 . GLU A 1 394 ? 127.984 79.967  139.813 1.00 467.18 ? 393 GLU A OE1 1 
ATOM   1825  O OE2 . GLU A 1 394 ? 128.774 81.488  138.429 1.00 512.02 ? 393 GLU A OE2 1 
ATOM   1826  N N   . SER A 1 395 ? 125.280 76.973  136.168 1.00 249.43 ? 394 SER A N   1 
ATOM   1827  C CA  . SER A 1 395 ? 125.668 75.747  135.485 1.00 265.50 ? 394 SER A CA  1 
ATOM   1828  C C   . SER A 1 395 ? 124.732 75.411  134.312 1.00 247.59 ? 394 SER A C   1 
ATOM   1829  O O   . SER A 1 395 ? 125.136 74.741  133.362 1.00 257.45 ? 394 SER A O   1 
ATOM   1830  C CB  . SER A 1 395 ? 125.713 74.593  136.478 1.00 300.21 ? 394 SER A CB  1 
ATOM   1831  O OG  . SER A 1 395 ? 126.507 74.879  137.628 1.00 274.38 ? 394 SER A OG  1 
ATOM   1832  N N   . ASN A 1 396 ? 123.478 75.860  134.381 1.00 188.29 ? 395 ASN A N   1 
ATOM   1833  C CA  . ASN A 1 396 ? 122.463 75.557  133.390 1.00 157.63 ? 395 ASN A CA  1 
ATOM   1834  C C   . ASN A 1 396 ? 122.068 76.858  132.721 1.00 179.02 ? 395 ASN A C   1 
ATOM   1835  O O   . ASN A 1 396 ? 121.694 77.826  133.382 1.00 166.76 ? 395 ASN A O   1 
ATOM   1836  C CB  . ASN A 1 396 ? 121.243 74.921  134.049 1.00 189.20 ? 395 ASN A CB  1 
ATOM   1837  C CG  . ASN A 1 396 ? 121.601 73.626  134.711 1.00 152.75 ? 395 ASN A CG  1 
ATOM   1838  O OD1 . ASN A 1 396 ? 121.993 72.706  134.008 1.00 219.29 ? 395 ASN A OD1 1 
ATOM   1839  N ND2 . ASN A 1 396 ? 121.506 73.557  136.030 1.00 187.98 ? 395 ASN A ND2 1 
ATOM   1840  N N   . LYS A 1 397 ? 122.143 76.885  131.400 1.00 181.06 ? 396 LYS A N   1 
ATOM   1841  C CA  . LYS A 1 397 ? 122.184 78.159  130.708 1.00 225.00 ? 396 LYS A CA  1 
ATOM   1842  C C   . LYS A 1 397 ? 120.932 78.370  129.850 1.00 175.37 ? 396 LYS A C   1 
ATOM   1843  O O   . LYS A 1 397 ? 120.639 79.522  129.554 1.00 209.02 ? 396 LYS A O   1 
ATOM   1844  C CB  . LYS A 1 397 ? 123.537 78.194  129.983 1.00 330.02 ? 396 LYS A CB  1 
ATOM   1845  C CG  . LYS A 1 397 ? 124.727 77.811  130.878 1.00 392.95 ? 396 LYS A CG  1 
ATOM   1846  C CD  . LYS A 1 397 ? 126.078 77.863  130.208 1.00 456.96 ? 396 LYS A CD  1 
ATOM   1847  C CE  . LYS A 1 397 ? 127.201 77.430  131.130 1.00 494.80 ? 396 LYS A CE  1 
ATOM   1848  N NZ  . LYS A 1 397 ? 127.495 78.440  132.174 1.00 514.11 ? 396 LYS A NZ  1 
ATOM   1849  N N   . ASP A 1 398 ? 120.225 77.289  129.460 1.00 172.94 ? 397 ASP A N   1 
ATOM   1850  C CA  . ASP A 1 398 ? 118.953 77.368  128.755 1.00 237.17 ? 397 ASP A CA  1 
ATOM   1851  C C   . ASP A 1 398 ? 117.884 76.627  129.563 1.00 178.49 ? 397 ASP A C   1 
ATOM   1852  O O   . ASP A 1 398 ? 117.105 75.821  129.060 1.00 248.64 ? 397 ASP A O   1 
ATOM   1853  C CB  . ASP A 1 398 ? 119.123 76.838  127.327 1.00 370.20 ? 397 ASP A CB  1 
ATOM   1854  C CG  . ASP A 1 398 ? 117.990 77.162  126.356 1.00 469.47 ? 397 ASP A CG  1 
ATOM   1855  O OD1 . ASP A 1 398 ? 117.091 77.956  126.727 1.00 427.68 ? 397 ASP A OD1 1 
ATOM   1856  O OD2 . ASP A 1 398 ? 118.010 76.611  125.228 1.00 561.59 ? 397 ASP A OD2 1 
ATOM   1857  N N   . LEU A 1 399 ? 117.868 76.933  130.853 1.00 124.26 ? 398 LEU A N   1 
ATOM   1858  C CA  . LEU A 1 399 ? 116.822 76.576  131.779 1.00 90.87  ? 398 LEU A CA  1 
ATOM   1859  C C   . LEU A 1 399 ? 115.978 77.816  132.040 1.00 83.18  ? 398 LEU A C   1 
ATOM   1860  O O   . LEU A 1 399 ? 116.533 78.873  132.350 1.00 172.02 ? 398 LEU A O   1 
ATOM   1861  C CB  . LEU A 1 399 ? 117.551 76.205  133.038 1.00 76.99  ? 398 LEU A CB  1 
ATOM   1862  C CG  . LEU A 1 399 ? 116.702 75.781  134.210 1.00 94.95  ? 398 LEU A CG  1 
ATOM   1863  C CD1 . LEU A 1 399 ? 116.660 74.249  134.154 1.00 99.06  ? 398 LEU A CD1 1 
ATOM   1864  C CD2 . LEU A 1 399 ? 117.190 76.367  135.587 1.00 107.67 ? 398 LEU A CD2 1 
ATOM   1865  N N   . LEU A 1 400 ? 114.664 77.742  131.870 1.00 74.82  ? 399 LEU A N   1 
ATOM   1866  C CA  . LEU A 1 400 ? 113.816 78.780  132.411 1.00 76.25  ? 399 LEU A CA  1 
ATOM   1867  C C   . LEU A 1 400 ? 113.712 78.484  133.875 1.00 59.98  ? 399 LEU A C   1 
ATOM   1868  O O   . LEU A 1 400 ? 113.387 77.358  134.217 1.00 69.30  ? 399 LEU A O   1 
ATOM   1869  C CB  . LEU A 1 400 ? 112.395 78.757  131.844 1.00 68.95  ? 399 LEU A CB  1 
ATOM   1870  C CG  . LEU A 1 400 ? 112.273 78.940  130.337 1.00 74.46  ? 399 LEU A CG  1 
ATOM   1871  C CD1 . LEU A 1 400 ? 110.898 79.541  129.969 1.00 66.19  ? 399 LEU A CD1 1 
ATOM   1872  C CD2 . LEU A 1 400 ? 113.436 79.707  129.702 1.00 85.17  ? 399 LEU A CD2 1 
ATOM   1873  N N   . LEU A 1 401 ? 113.888 79.498  134.696 1.00 52.68  ? 400 LEU A N   1 
ATOM   1874  C CA  . LEU A 1 401 ? 113.650 79.316  136.095 1.00 59.77  ? 400 LEU A CA  1 
ATOM   1875  C C   . LEU A 1 401 ? 112.673 80.409  136.536 1.00 74.41  ? 400 LEU A C   1 
ATOM   1876  O O   . LEU A 1 401 ? 113.040 81.584  136.745 1.00 88.16  ? 400 LEU A O   1 
ATOM   1877  C CB  . LEU A 1 401 ? 115.020 79.422  136.733 1.00 75.94  ? 400 LEU A CB  1 
ATOM   1878  C CG  . LEU A 1 401 ? 115.045 79.548  138.223 1.00 87.17  ? 400 LEU A CG  1 
ATOM   1879  C CD1 . LEU A 1 401 ? 114.346 78.327  138.766 1.00 91.90  ? 400 LEU A CD1 1 
ATOM   1880  C CD2 . LEU A 1 401 ? 116.501 79.640  138.619 1.00 114.24 ? 400 LEU A CD2 1 
ATOM   1881  N N   . THR A 1 402 ? 111.426 79.982  136.692 1.00 61.42  ? 401 THR A N   1 
ATOM   1882  C CA  . THR A 1 402 ? 110.383 80.746  137.328 1.00 66.77  ? 401 THR A CA  1 
ATOM   1883  C C   . THR A 1 402 ? 110.618 80.786  138.841 1.00 98.95  ? 401 THR A C   1 
ATOM   1884  O O   . THR A 1 402 ? 111.147 79.846  139.408 1.00 90.61  ? 401 THR A O   1 
ATOM   1885  C CB  . THR A 1 402 ? 108.997 80.138  137.040 1.00 84.17  ? 401 THR A CB  1 
ATOM   1886  O OG1 . THR A 1 402 ? 108.814 78.815  137.565 1.00 53.81  ? 401 THR A OG1 1 
ATOM   1887  C CG2 . THR A 1 402 ? 108.696 80.206  135.550 1.00 90.03  ? 401 THR A CG2 1 
ATOM   1888  N N   . SER A 1 403 ? 110.247 81.899  139.495 1.00 117.72 ? 402 SER A N   1 
ATOM   1889  C CA  . SER A 1 403 ? 110.668 82.206  140.864 1.00 75.42  ? 402 SER A CA  1 
ATOM   1890  C C   . SER A 1 403 ? 109.773 83.255  141.449 1.00 72.47  ? 402 SER A C   1 
ATOM   1891  O O   . SER A 1 403 ? 108.932 83.843  140.733 1.00 106.55 ? 402 SER A O   1 
ATOM   1892  C CB  . SER A 1 403 ? 112.012 82.757  140.914 1.00 77.48  ? 402 SER A CB  1 
ATOM   1893  O OG  . SER A 1 403 ? 111.994 84.045  140.276 1.00 79.17  ? 402 SER A OG  1 
ATOM   1894  N N   . SER A 1 404 ? 109.970 83.467  142.750 1.00 70.05  ? 403 SER A N   1 
ATOM   1895  C CA  . SER A 1 404 ? 109.244 84.536  143.415 1.00 96.82  ? 403 SER A CA  1 
ATOM   1896  C C   . SER A 1 404 ? 109.986 85.860  143.227 1.00 73.85  ? 403 SER A C   1 
ATOM   1897  O O   . SER A 1 404 ? 109.639 86.835  143.887 1.00 65.78  ? 403 SER A O   1 
ATOM   1898  C CB  . SER A 1 404 ? 108.972 84.235  144.869 1.00 107.66 ? 403 SER A CB  1 
ATOM   1899  O OG  . SER A 1 404 ? 108.300 82.991  145.018 1.00 147.48 ? 403 SER A OG  1 
ATOM   1900  N N   . TYR A 1 405 ? 110.954 85.975  142.317 1.00 56.39  ? 404 TYR A N   1 
ATOM   1901  C CA  . TYR A 1 405 ? 111.813 87.140  142.417 1.00 58.45  ? 404 TYR A CA  1 
ATOM   1902  C C   . TYR A 1 405 ? 111.128 88.456  142.134 1.00 58.91  ? 404 TYR A C   1 
ATOM   1903  O O   . TYR A 1 405 ? 111.407 89.370  142.951 1.00 65.42  ? 404 TYR A O   1 
ATOM   1904  C CB  . TYR A 1 405 ? 112.949 87.065  141.432 1.00 75.29  ? 404 TYR A CB  1 
ATOM   1905  C CG  . TYR A 1 405 ? 113.825 88.289  141.307 1.00 50.81  ? 404 TYR A CG  1 
ATOM   1906  C CD1 . TYR A 1 405 ? 114.659 88.663  142.290 1.00 85.02  ? 404 TYR A CD1 1 
ATOM   1907  C CD2 . TYR A 1 405 ? 113.761 89.060  140.199 1.00 51.51  ? 404 TYR A CD2 1 
ATOM   1908  C CE1 . TYR A 1 405 ? 115.454 89.787  142.159 1.00 128.02 ? 404 TYR A CE1 1 
ATOM   1909  C CE2 . TYR A 1 405 ? 114.536 90.151  140.027 1.00 69.46  ? 404 TYR A CE2 1 
ATOM   1910  C CZ  . TYR A 1 405 ? 115.406 90.542  141.010 1.00 103.45 ? 404 TYR A CZ  1 
ATOM   1911  O OH  . TYR A 1 405 ? 116.155 91.678  140.802 1.00 98.98  ? 404 TYR A OH  1 
ATOM   1912  N N   . LEU A 1 406 ? 110.293 88.538  141.056 1.00 51.27  ? 405 LEU A N   1 
ATOM   1913  C CA  . LEU A 1 406 ? 109.475 89.751  140.968 1.00 61.16  ? 405 LEU A CA  1 
ATOM   1914  C C   . LEU A 1 406 ? 108.279 89.906  141.953 1.00 69.22  ? 405 LEU A C   1 
ATOM   1915  O O   . LEU A 1 406 ? 107.654 90.990  141.885 1.00 74.73  ? 405 LEU A O   1 
ATOM   1916  C CB  . LEU A 1 406 ? 108.928 89.866  139.573 1.00 61.54  ? 405 LEU A CB  1 
ATOM   1917  C CG  . LEU A 1 406 ? 109.808 90.409  138.499 1.00 76.85  ? 405 LEU A CG  1 
ATOM   1918  C CD1 . LEU A 1 406 ? 108.916 90.976  137.393 1.00 76.61  ? 405 LEU A CD1 1 
ATOM   1919  C CD2 . LEU A 1 406 ? 110.657 91.506  139.032 1.00 111.93 ? 405 LEU A CD2 1 
ATOM   1920  N N   . SER A 1 407 ? 107.976 88.919  142.846 1.00 60.26  ? 406 SER A N   1 
ATOM   1921  C CA  . SER A 1 407 ? 106.834 88.887  143.766 1.00 82.11  ? 406 SER A CA  1 
ATOM   1922  C C   . SER A 1 407 ? 106.819 90.033  144.782 1.00 120.33 ? 406 SER A C   1 
ATOM   1923  O O   . SER A 1 407 ? 105.756 90.608  145.024 1.00 118.55 ? 406 SER A O   1 
ATOM   1924  C CB  . SER A 1 407 ? 106.854 87.576  144.517 1.00 112.56 ? 406 SER A CB  1 
ATOM   1925  O OG  . SER A 1 407 ? 105.751 87.405  145.367 1.00 157.71 ? 406 SER A OG  1 
ATOM   1926  N N   . ASP A 1 408 ? 108.003 90.362  145.337 1.00 172.64 ? 407 ASP A N   1 
ATOM   1927  C CA  . ASP A 1 408 ? 108.221 91.288  146.450 1.00 193.50 ? 407 ASP A CA  1 
ATOM   1928  C C   . ASP A 1 408 ? 108.237 92.748  145.967 1.00 155.73 ? 407 ASP A C   1 
ATOM   1929  O O   . ASP A 1 408 ? 109.143 93.515  146.281 1.00 152.37 ? 407 ASP A O   1 
ATOM   1930  C CB  . ASP A 1 408 ? 109.548 90.953  147.160 1.00 277.83 ? 407 ASP A CB  1 
ATOM   1931  C CG  . ASP A 1 408 ? 109.727 89.505  147.613 1.00 389.61 ? 407 ASP A CG  1 
ATOM   1932  O OD1 . ASP A 1 408 ? 108.712 88.904  148.038 1.00 437.40 ? 407 ASP A OD1 1 
ATOM   1933  O OD2 . ASP A 1 408 ? 110.885 88.983  147.553 1.00 413.30 ? 407 ASP A OD2 1 
ATOM   1934  N N   . SER A 1 409 ? 107.218 93.139  145.193 1.00 201.83 ? 408 SER A N   1 
ATOM   1935  C CA  . SER A 1 409 ? 107.238 94.314  144.327 1.00 170.04 ? 408 SER A CA  1 
ATOM   1936  C C   . SER A 1 409 ? 107.089 95.642  145.074 1.00 147.52 ? 408 SER A C   1 
ATOM   1937  O O   . SER A 1 409 ? 107.149 96.662  144.434 1.00 112.57 ? 408 SER A O   1 
ATOM   1938  C CB  . SER A 1 409 ? 106.096 94.206  143.340 1.00 212.19 ? 408 SER A CB  1 
ATOM   1939  O OG  . SER A 1 409 ? 104.832 94.278  144.022 1.00 240.94 ? 408 SER A OG  1 
ATOM   1940  N N   . GLY A 1 410 ? 106.847 95.670  146.394 1.00 172.21 ? 409 GLY A N   1 
ATOM   1941  C CA  . GLY A 1 410 ? 106.527 96.925  147.075 1.00 231.76 ? 409 GLY A CA  1 
ATOM   1942  C C   . GLY A 1 410 ? 105.041 97.335  147.084 1.00 177.54 ? 409 GLY A C   1 
ATOM   1943  O O   . GLY A 1 410 ? 104.659 98.268  147.818 1.00 129.36 ? 409 GLY A O   1 
ATOM   1944  N N   . SER A 1 411 ? 104.190 96.659  146.300 1.00 152.73 ? 410 SER A N   1 
ATOM   1945  C CA  . SER A 1 411 ? 102.735 96.760  146.428 1.00 231.43 ? 410 SER A CA  1 
ATOM   1946  C C   . SER A 1 411 ? 102.205 98.210  146.295 1.00 160.85 ? 410 SER A C   1 
ATOM   1947  O O   . SER A 1 411 ? 101.062 98.557  146.694 1.00 153.76 ? 410 SER A O   1 
ATOM   1948  C CB  . SER A 1 411 ? 102.264 96.050  147.679 1.00 327.39 ? 410 SER A CB  1 
ATOM   1949  O OG  . SER A 1 411 ? 102.615 94.673  147.605 1.00 295.54 ? 410 SER A OG  1 
ATOM   1950  N N   . THR A 1 412 ? 103.021 99.068  145.674 1.00 140.94 ? 411 THR A N   1 
ATOM   1951  C CA  . THR A 1 412 ? 102.534 100.006 144.661 1.00 173.43 ? 411 THR A CA  1 
ATOM   1952  C C   . THR A 1 412 ? 103.528 99.995  143.506 1.00 131.91 ? 411 THR A C   1 
ATOM   1953  O O   . THR A 1 412 ? 103.893 101.036 143.009 1.00 112.01 ? 411 THR A O   1 
ATOM   1954  C CB  . THR A 1 412 ? 102.304 101.355 145.336 1.00 240.99 ? 411 THR A CB  1 
ATOM   1955  O OG1 . THR A 1 412 ? 101.190 101.206 146.219 1.00 341.35 ? 411 THR A OG1 1 
ATOM   1956  C CG2 . THR A 1 412 ? 102.006 102.471 144.371 1.00 198.38 ? 411 THR A CG2 1 
ATOM   1957  N N   . GLY A 1 413 ? 104.020 98.796  143.124 1.00 124.97 ? 412 GLY A N   1 
ATOM   1958  C CA  . GLY A 1 413 ? 104.986 98.565  142.063 1.00 129.57 ? 412 GLY A CA  1 
ATOM   1959  C C   . GLY A 1 413 ? 106.375 99.169  142.295 1.00 113.49 ? 412 GLY A C   1 
ATOM   1960  O O   . GLY A 1 413 ? 107.246 99.012  141.455 1.00 117.00 ? 412 GLY A O   1 
ATOM   1961  N N   . GLU A 1 414 ? 106.636 99.823  143.420 1.00 95.62  ? 413 GLU A N   1 
ATOM   1962  C CA  . GLU A 1 414 ? 107.625 100.886 143.475 1.00 97.88  ? 413 GLU A CA  1 
ATOM   1963  C C   . GLU A 1 414 ? 109.032 100.382 143.155 1.00 99.35  ? 413 GLU A C   1 
ATOM   1964  O O   . GLU A 1 414 ? 109.849 101.110 142.571 1.00 143.68 ? 413 GLU A O   1 
ATOM   1965  C CB  . GLU A 1 414 ? 107.490 101.594 144.826 1.00 122.74 ? 413 GLU A CB  1 
ATOM   1966  C CG  . GLU A 1 414 ? 107.925 100.821 146.071 1.00 155.55 ? 413 GLU A CG  1 
ATOM   1967  C CD  . GLU A 1 414 ? 107.352 101.376 147.380 1.00 302.47 ? 413 GLU A CD  1 
ATOM   1968  O OE1 . GLU A 1 414 ? 106.304 102.077 147.338 1.00 356.29 ? 413 GLU A OE1 1 
ATOM   1969  O OE2 . GLU A 1 414 ? 107.940 101.129 148.454 1.00 319.19 ? 413 GLU A OE2 1 
ATOM   1970  N N   . HIS A 1 415 ? 109.297 99.134  143.526 1.00 100.67 ? 414 HIS A N   1 
ATOM   1971  C CA  . HIS A 1 415 ? 110.594 98.508  143.346 1.00 122.83 ? 414 HIS A CA  1 
ATOM   1972  C C   . HIS A 1 415 ? 110.819 97.970  141.943 1.00 103.15 ? 414 HIS A C   1 
ATOM   1973  O O   . HIS A 1 415 ? 111.951 97.699  141.598 1.00 109.17 ? 414 HIS A O   1 
ATOM   1974  C CB  . HIS A 1 415 ? 110.749 97.357  144.345 1.00 136.31 ? 414 HIS A CB  1 
ATOM   1975  C CG  . HIS A 1 415 ? 110.871 97.855  145.737 1.00 134.79 ? 414 HIS A CG  1 
ATOM   1976  N ND1 . HIS A 1 415 ? 110.357 97.232  146.859 1.00 205.76 ? 414 HIS A ND1 1 
ATOM   1977  C CD2 . HIS A 1 415 ? 111.473 98.960  146.144 1.00 128.90 ? 414 HIS A CD2 1 
ATOM   1978  C CE1 . HIS A 1 415 ? 110.647 97.969  147.914 1.00 220.20 ? 414 HIS A CE1 1 
ATOM   1979  N NE2 . HIS A 1 415 ? 111.333 99.014  147.498 1.00 214.75 ? 414 HIS A NE2 1 
ATOM   1980  N N   . THR A 1 416 ? 109.784 97.836  141.132 1.00 93.00  ? 415 THR A N   1 
ATOM   1981  C CA  . THR A 1 416 ? 109.873 97.046  139.924 1.00 67.69  ? 415 THR A CA  1 
ATOM   1982  C C   . THR A 1 416 ? 110.899 97.524  138.909 1.00 74.88  ? 415 THR A C   1 
ATOM   1983  O O   . THR A 1 416 ? 111.575 96.663  138.350 1.00 49.80  ? 415 THR A O   1 
ATOM   1984  C CB  . THR A 1 416 ? 108.499 96.948  139.285 1.00 62.91  ? 415 THR A CB  1 
ATOM   1985  O OG1 . THR A 1 416 ? 107.829 96.088  140.183 1.00 104.01 ? 415 THR A OG1 1 
ATOM   1986  C CG2 . THR A 1 416 ? 108.513 96.156  138.018 1.00 111.04 ? 415 THR A CG2 1 
ATOM   1987  N N   . LYS A 1 417 ? 111.023 98.845  138.650 1.00 94.89  ? 416 LYS A N   1 
ATOM   1988  C CA  . LYS A 1 417 ? 112.026 99.287  137.691 1.00 74.41  ? 416 LYS A CA  1 
ATOM   1989  C C   . LYS A 1 417 ? 113.350 98.658  138.060 1.00 83.21  ? 416 LYS A C   1 
ATOM   1990  O O   . LYS A 1 417 ? 114.120 98.387  137.148 1.00 97.29  ? 416 LYS A O   1 
ATOM   1991  C CB  . LYS A 1 417 ? 112.219 100.804 137.625 1.00 99.83  ? 416 LYS A CB  1 
ATOM   1992  C CG  . LYS A 1 417 ? 113.284 101.272 136.622 1.00 111.04 ? 416 LYS A CG  1 
ATOM   1993  C CD  . LYS A 1 417 ? 113.313 102.738 136.189 1.00 142.22 ? 416 LYS A CD  1 
ATOM   1994  C CE  . LYS A 1 417 ? 114.579 103.037 135.394 1.00 215.76 ? 416 LYS A CE  1 
ATOM   1995  N NZ  . LYS A 1 417 ? 115.106 104.410 135.671 1.00 349.48 ? 416 LYS A NZ  1 
ATOM   1996  N N   . SER A 1 418 ? 113.585 98.461  139.376 1.00 92.67  ? 417 SER A N   1 
ATOM   1997  C CA  . SER A 1 418 ? 114.886 98.112  139.894 1.00 97.67  ? 417 SER A CA  1 
ATOM   1998  C C   . SER A 1 418 ? 115.006 96.609  139.954 1.00 70.93  ? 417 SER A C   1 
ATOM   1999  O O   . SER A 1 418 ? 116.080 96.110  139.589 1.00 114.45 ? 417 SER A O   1 
ATOM   2000  C CB  . SER A 1 418 ? 115.159 98.777  141.236 1.00 154.11 ? 417 SER A CB  1 
ATOM   2001  O OG  . SER A 1 418 ? 114.554 98.101  142.340 1.00 145.02 ? 417 SER A OG  1 
ATOM   2002  N N   . LEU A 1 419 ? 113.953 95.895  140.390 1.00 60.27  ? 418 LEU A N   1 
ATOM   2003  C CA  . LEU A 1 419 ? 114.067 94.438  140.379 1.00 68.77  ? 418 LEU A CA  1 
ATOM   2004  C C   . LEU A 1 419 ? 114.261 93.914  138.962 1.00 55.91  ? 418 LEU A C   1 
ATOM   2005  O O   . LEU A 1 419 ? 115.049 93.006  138.765 1.00 48.47  ? 418 LEU A O   1 
ATOM   2006  C CB  . LEU A 1 419 ? 112.843 93.753  140.926 1.00 55.21  ? 418 LEU A CB  1 
ATOM   2007  C CG  . LEU A 1 419 ? 112.671 93.980  142.374 1.00 84.75  ? 418 LEU A CG  1 
ATOM   2008  C CD1 . LEU A 1 419 ? 111.279 93.444  142.790 1.00 144.80 ? 418 LEU A CD1 1 
ATOM   2009  C CD2 . LEU A 1 419 ? 113.875 93.363  143.108 1.00 117.37 ? 418 LEU A CD2 1 
ATOM   2010  N N   . VAL A 1 420 ? 113.575 94.500  137.995 1.00 44.01  ? 419 VAL A N   1 
ATOM   2011  C CA  . VAL A 1 420 ? 113.729 94.056  136.634 1.00 44.47  ? 419 VAL A CA  1 
ATOM   2012  C C   . VAL A 1 420 ? 115.093 94.404  136.089 1.00 53.37  ? 419 VAL A C   1 
ATOM   2013  O O   . VAL A 1 420 ? 115.725 93.541  135.528 1.00 56.02  ? 419 VAL A O   1 
ATOM   2014  C CB  . VAL A 1 420 ? 112.670 94.648  135.715 1.00 48.65  ? 419 VAL A CB  1 
ATOM   2015  C CG1 . VAL A 1 420 ? 113.023 94.381  134.275 1.00 49.93  ? 419 VAL A CG1 1 
ATOM   2016  C CG2 . VAL A 1 420 ? 111.281 94.076  135.983 1.00 50.89  ? 419 VAL A CG2 1 
ATOM   2017  N N   . THR A 1 421 ? 115.538 95.641  136.207 1.00 62.13  ? 420 THR A N   1 
ATOM   2018  C CA  . THR A 1 421 ? 116.761 95.967  135.528 1.00 72.07  ? 420 THR A CA  1 
ATOM   2019  C C   . THR A 1 421 ? 117.977 95.422  136.229 1.00 79.86  ? 420 THR A C   1 
ATOM   2020  O O   . THR A 1 421 ? 119.003 95.360  135.558 1.00 126.95 ? 420 THR A O   1 
ATOM   2021  C CB  . THR A 1 421 ? 116.952 97.477  135.389 1.00 93.49  ? 420 THR A CB  1 
ATOM   2022  O OG1 . THR A 1 421 ? 116.903 98.225  136.596 1.00 120.97 ? 420 THR A OG1 1 
ATOM   2023  C CG2 . THR A 1 421 ? 115.861 98.030  134.531 1.00 118.51 ? 420 THR A CG2 1 
ATOM   2024  N N   . GLN A 1 422 ? 117.928 95.130  137.534 1.00 97.84  ? 421 GLN A N   1 
ATOM   2025  C CA  . GLN A 1 422 ? 119.058 94.461  138.139 1.00 120.55 ? 421 GLN A CA  1 
ATOM   2026  C C   . GLN A 1 422 ? 119.111 93.070  137.565 1.00 72.64  ? 421 GLN A C   1 
ATOM   2027  O O   . GLN A 1 422 ? 120.204 92.589  137.319 1.00 112.85 ? 421 GLN A O   1 
ATOM   2028  C CB  . GLN A 1 422 ? 119.008 94.362  139.654 1.00 139.31 ? 421 GLN A CB  1 
ATOM   2029  C CG  . GLN A 1 422 ? 119.411 95.654  140.327 1.00 171.78 ? 421 GLN A CG  1 
ATOM   2030  C CD  . GLN A 1 422 ? 119.159 95.531  141.813 1.00 299.58 ? 421 GLN A CD  1 
ATOM   2031  O OE1 . GLN A 1 422 ? 118.753 94.482  142.318 1.00 308.49 ? 421 GLN A OE1 1 
ATOM   2032  N NE2 . GLN A 1 422 ? 119.399 96.612  142.540 1.00 393.99 ? 421 GLN A NE2 1 
ATOM   2033  N N   . TYR A 1 423 ? 117.982 92.422  137.380 1.00 55.46  ? 422 TYR A N   1 
ATOM   2034  C CA  . TYR A 1 423 ? 118.077 91.014  137.019 1.00 69.74  ? 422 TYR A CA  1 
ATOM   2035  C C   . TYR A 1 423 ? 118.585 90.830  135.604 1.00 62.12  ? 422 TYR A C   1 
ATOM   2036  O O   . TYR A 1 423 ? 119.408 89.987  135.354 1.00 77.96  ? 422 TYR A O   1 
ATOM   2037  C CB  . TYR A 1 423 ? 116.728 90.380  137.183 1.00 59.82  ? 422 TYR A CB  1 
ATOM   2038  C CG  . TYR A 1 423 ? 116.675 88.908  136.967 1.00 52.61  ? 422 TYR A CG  1 
ATOM   2039  C CD1 . TYR A 1 423 ? 116.669 88.400  135.733 1.00 67.12  ? 422 TYR A CD1 1 
ATOM   2040  C CD2 . TYR A 1 423 ? 116.566 88.057  138.016 1.00 111.87 ? 422 TYR A CD2 1 
ATOM   2041  C CE1 . TYR A 1 423 ? 116.567 87.052  135.484 1.00 117.81 ? 422 TYR A CE1 1 
ATOM   2042  C CE2 . TYR A 1 423 ? 116.475 86.694  137.803 1.00 171.80 ? 422 TYR A CE2 1 
ATOM   2043  C CZ  . TYR A 1 423 ? 116.470 86.180  136.527 1.00 123.05 ? 422 TYR A CZ  1 
ATOM   2044  O OH  . TYR A 1 423 ? 116.390 84.841  136.301 1.00 175.89 ? 422 TYR A OH  1 
ATOM   2045  N N   . LEU A 1 424 ? 118.104 91.625  134.701 1.00 56.21  ? 423 LEU A N   1 
ATOM   2046  C CA  . LEU A 1 424 ? 118.636 91.623  133.381 1.00 55.87  ? 423 LEU A CA  1 
ATOM   2047  C C   . LEU A 1 424 ? 120.129 91.843  133.454 1.00 90.00  ? 423 LEU A C   1 
ATOM   2048  O O   . LEU A 1 424 ? 120.855 91.077  132.827 1.00 121.60 ? 423 LEU A O   1 
ATOM   2049  C CB  . LEU A 1 424 ? 117.921 92.736  132.597 1.00 75.09  ? 423 LEU A CB  1 
ATOM   2050  C CG  . LEU A 1 424 ? 116.530 92.292  132.096 1.00 73.84  ? 423 LEU A CG  1 
ATOM   2051  C CD1 . LEU A 1 424 ? 115.580 93.344  131.441 1.00 73.48  ? 423 LEU A CD1 1 
ATOM   2052  C CD2 . LEU A 1 424 ? 116.757 91.204  131.070 1.00 85.96  ? 423 LEU A CD2 1 
ATOM   2053  N N   . ASN A 1 425 ? 120.589 92.881  134.161 1.00 100.04 ? 424 ASN A N   1 
ATOM   2054  C CA  . ASN A 1 425 ? 122.016 93.195  134.255 1.00 133.74 ? 424 ASN A CA  1 
ATOM   2055  C C   . ASN A 1 425 ? 122.838 92.048  134.846 1.00 99.94  ? 424 ASN A C   1 
ATOM   2056  O O   . ASN A 1 425 ? 123.856 91.644  134.296 1.00 130.59 ? 424 ASN A O   1 
ATOM   2057  C CB  . ASN A 1 425 ? 122.243 94.441  135.087 1.00 150.51 ? 424 ASN A CB  1 
ATOM   2058  C CG  . ASN A 1 425 ? 123.613 95.076  134.963 1.00 176.20 ? 424 ASN A CG  1 
ATOM   2059  O OD1 . ASN A 1 425 ? 124.181 95.173  133.867 1.00 158.66 ? 424 ASN A OD1 1 
ATOM   2060  N ND2 . ASN A 1 425 ? 124.123 95.522  136.106 1.00 243.73 ? 424 ASN A ND2 1 
ATOM   2061  N N   . ALA A 1 426 ? 122.377 91.495  135.937 1.00 91.04  ? 425 ALA A N   1 
ATOM   2062  C CA  . ALA A 1 426 ? 123.070 90.400  136.582 1.00 121.48 ? 425 ALA A CA  1 
ATOM   2063  C C   . ALA A 1 426 ? 123.211 89.152  135.692 1.00 103.61 ? 425 ALA A C   1 
ATOM   2064  O O   . ALA A 1 426 ? 124.291 88.555  135.647 1.00 146.71 ? 425 ALA A O   1 
ATOM   2065  C CB  . ALA A 1 426 ? 122.363 90.094  137.890 1.00 125.99 ? 425 ALA A CB  1 
ATOM   2066  N N   . THR A 1 427 ? 122.144 88.749  135.005 1.00 91.76  ? 426 THR A N   1 
ATOM   2067  C CA  . THR A 1 427 ? 122.193 87.597  134.124 1.00 129.93 ? 426 THR A CA  1 
ATOM   2068  C C   . THR A 1 427 ? 122.907 87.911  132.809 1.00 130.40 ? 426 THR A C   1 
ATOM   2069  O O   . THR A 1 427 ? 123.232 86.988  132.062 1.00 184.09 ? 426 THR A O   1 
ATOM   2070  C CB  . THR A 1 427 ? 120.789 87.024  133.834 1.00 163.18 ? 426 THR A CB  1 
ATOM   2071  O OG1 . THR A 1 427 ? 119.985 88.029  133.215 1.00 106.37 ? 426 THR A OG1 1 
ATOM   2072  C CG2 . THR A 1 427 ? 120.124 86.462  135.076 1.00 148.05 ? 426 THR A CG2 1 
ATOM   2073  N N   . GLY A 1 428 ? 123.158 89.173  132.503 1.00 112.58 ? 427 GLY A N   1 
ATOM   2074  C CA  . GLY A 1 428 ? 123.855 89.498  131.268 1.00 171.38 ? 427 GLY A CA  1 
ATOM   2075  C C   . GLY A 1 428 ? 122.948 89.426  130.036 1.00 155.24 ? 427 GLY A C   1 
ATOM   2076  O O   . GLY A 1 428 ? 123.412 89.110  128.939 1.00 188.41 ? 427 GLY A O   1 
ATOM   2077  N N   . ASN A 1 429 ? 121.663 89.732  130.239 1.00 142.25 ? 428 ASN A N   1 
ATOM   2078  C CA  . ASN A 1 429 ? 120.662 89.792  129.191 1.00 148.62 ? 428 ASN A CA  1 
ATOM   2079  C C   . ASN A 1 429 ? 120.553 88.453  128.459 1.00 151.98 ? 428 ASN A C   1 
ATOM   2080  O O   . ASN A 1 429 ? 120.383 88.421  127.237 1.00 199.15 ? 428 ASN A O   1 
ATOM   2081  C CB  . ASN A 1 429 ? 120.938 91.035  128.333 1.00 183.95 ? 428 ASN A CB  1 
ATOM   2082  C CG  . ASN A 1 429 ? 120.467 92.333  128.979 1.00 210.58 ? 428 ASN A CG  1 
ATOM   2083  O OD1 . ASN A 1 429 ? 120.819 92.614  130.124 1.00 215.74 ? 428 ASN A OD1 1 
ATOM   2084  N ND2 . ASN A 1 429 ? 119.664 93.132  128.275 1.00 216.13 ? 428 ASN A ND2 1 
ATOM   2085  N N   . ARG A 1 430 ? 120.613 87.335  129.211 1.00 140.89 ? 429 ARG A N   1 
ATOM   2086  C CA  . ARG A 1 430 ? 120.263 86.015  128.665 1.00 157.91 ? 429 ARG A CA  1 
ATOM   2087  C C   . ARG A 1 430 ? 118.736 85.954  128.426 1.00 157.90 ? 429 ARG A C   1 
ATOM   2088  O O   . ARG A 1 430 ? 117.996 86.953  128.579 1.00 143.01 ? 429 ARG A O   1 
ATOM   2089  C CB  . ARG A 1 430 ? 120.869 84.905  129.547 1.00 152.84 ? 429 ARG A CB  1 
ATOM   2090  C CG  . ARG A 1 430 ? 122.379 84.726  129.367 1.00 174.13 ? 429 ARG A CG  1 
ATOM   2091  C CD  . ARG A 1 430 ? 122.993 83.613  130.211 1.00 204.29 ? 429 ARG A CD  1 
ATOM   2092  N NE  . ARG A 1 430 ? 123.191 83.990  131.610 1.00 218.09 ? 429 ARG A NE  1 
ATOM   2093  C CZ  . ARG A 1 430 ? 123.452 83.185  132.659 1.00 245.01 ? 429 ARG A CZ  1 
ATOM   2094  N NH1 . ARG A 1 430 ? 123.781 83.741  133.816 1.00 225.57 ? 429 ARG A NH1 1 
ATOM   2095  N NH2 . ARG A 1 430 ? 123.398 81.859  132.589 1.00 290.46 ? 429 ARG A NH2 1 
ATOM   2096  N N   . TRP A 1 431 ? 118.224 84.779  128.027 1.00 103.60 ? 430 TRP A N   1 
ATOM   2097  C CA  . TRP A 1 431 ? 116.772 84.598  128.097 1.00 92.16  ? 430 TRP A CA  1 
ATOM   2098  C C   . TRP A 1 431 ? 116.293 84.362  129.536 1.00 127.74 ? 430 TRP A C   1 
ATOM   2099  O O   . TRP A 1 431 ? 117.006 83.846  130.407 1.00 181.18 ? 430 TRP A O   1 
ATOM   2100  C CB  . TRP A 1 431 ? 116.379 83.412  127.225 1.00 119.15 ? 430 TRP A CB  1 
ATOM   2101  C CG  . TRP A 1 431 ? 114.995 83.617  126.701 1.00 90.40  ? 430 TRP A CG  1 
ATOM   2102  C CD1 . TRP A 1 431 ? 113.866 82.944  127.045 1.00 86.26  ? 430 TRP A CD1 1 
ATOM   2103  C CD2 . TRP A 1 431 ? 114.601 84.590  125.724 1.00 83.80  ? 430 TRP A CD2 1 
ATOM   2104  N NE1 . TRP A 1 431 ? 112.787 83.442  126.368 1.00 67.53  ? 430 TRP A NE1 1 
ATOM   2105  C CE2 . TRP A 1 431 ? 113.213 84.442  125.551 1.00 72.36  ? 430 TRP A CE2 1 
ATOM   2106  C CE3 . TRP A 1 431 ? 115.286 85.550  124.989 1.00 108.84 ? 430 TRP A CE3 1 
ATOM   2107  C CZ2 . TRP A 1 431 ? 112.486 85.233  124.695 1.00 59.93  ? 430 TRP A CZ2 1 
ATOM   2108  C CZ3 . TRP A 1 431 ? 114.569 86.318  124.116 1.00 146.31 ? 430 TRP A CZ3 1 
ATOM   2109  C CH2 . TRP A 1 431 ? 113.189 86.168  123.988 1.00 110.28 ? 430 TRP A CH2 1 
ATOM   2110  N N   . CYS A 1 432 ? 115.058 84.767  129.802 1.00 104.40 ? 431 CYS A N   1 
ATOM   2111  C CA  . CYS A 1 432 ? 114.482 84.773  131.144 1.00 101.58 ? 431 CYS A CA  1 
ATOM   2112  C C   . CYS A 1 432 ? 113.067 84.217  131.074 1.00 78.35  ? 431 CYS A C   1 
ATOM   2113  O O   . CYS A 1 432 ? 112.457 84.137  130.016 1.00 117.89 ? 431 CYS A O   1 
ATOM   2114  C CB  . CYS A 1 432 ? 114.407 86.212  131.679 1.00 72.63  ? 431 CYS A CB  1 
ATOM   2115  S SG  . CYS A 1 432 ? 115.949 87.102  131.408 1.00 221.35 ? 431 CYS A SG  1 
ATOM   2116  N N   . SER A 1 433 ? 112.493 83.894  132.184 1.00 66.88  ? 432 SER A N   1 
ATOM   2117  C CA  . SER A 1 433 ? 111.058 83.758  132.206 1.00 81.60  ? 432 SER A CA  1 
ATOM   2118  C C   . SER A 1 433 ? 110.383 84.701  133.201 1.00 74.86  ? 432 SER A C   1 
ATOM   2119  O O   . SER A 1 433 ? 110.352 84.390  134.377 1.00 66.71  ? 432 SER A O   1 
ATOM   2120  C CB  . SER A 1 433 ? 110.736 82.313  132.555 1.00 131.77 ? 432 SER A CB  1 
ATOM   2121  O OG  . SER A 1 433 ? 111.390 81.806  133.715 1.00 74.26  ? 432 SER A OG  1 
ATOM   2122  N N   . TRP A 1 434 ? 109.798 85.769  132.730 1.00 55.75  ? 433 TRP A N   1 
ATOM   2123  C CA  . TRP A 1 434 ? 109.071 86.616  133.631 1.00 58.64  ? 433 TRP A CA  1 
ATOM   2124  C C   . TRP A 1 434 ? 107.779 86.040  134.216 1.00 49.14  ? 433 TRP A C   1 
ATOM   2125  O O   . TRP A 1 434 ? 106.918 85.649  133.469 1.00 47.52  ? 433 TRP A O   1 
ATOM   2126  C CB  . TRP A 1 434 ? 108.817 87.880  132.833 1.00 64.20  ? 433 TRP A CB  1 
ATOM   2127  C CG  . TRP A 1 434 ? 110.147 88.499  132.509 1.00 68.07  ? 433 TRP A CG  1 
ATOM   2128  C CD1 . TRP A 1 434 ? 110.616 88.553  131.260 1.00 91.40  ? 433 TRP A CD1 1 
ATOM   2129  C CD2 . TRP A 1 434 ? 111.147 89.131  133.344 1.00 75.77  ? 433 TRP A CD2 1 
ATOM   2130  N NE1 . TRP A 1 434 ? 111.822 89.177  131.247 1.00 97.32  ? 433 TRP A NE1 1 
ATOM   2131  C CE2 . TRP A 1 434 ? 112.165 89.531  132.497 1.00 74.82  ? 433 TRP A CE2 1 
ATOM   2132  C CE3 . TRP A 1 434 ? 111.286 89.407  134.708 1.00 98.63  ? 433 TRP A CE3 1 
ATOM   2133  C CZ2 . TRP A 1 434 ? 113.286 90.170  132.940 1.00 94.96  ? 433 TRP A CZ2 1 
ATOM   2134  C CZ3 . TRP A 1 434 ? 112.410 90.029  135.160 1.00 86.97  ? 433 TRP A CZ3 1 
ATOM   2135  C CH2 . TRP A 1 434 ? 113.383 90.419  134.279 1.00 111.37 ? 433 TRP A CH2 1 
ATOM   2136  N N   . SER A 1 435 ? 107.661 86.024  135.538 1.00 47.36  ? 434 SER A N   1 
ATOM   2137  C CA  . SER A 1 435 ? 106.572 85.384  136.225 1.00 64.93  ? 434 SER A CA  1 
ATOM   2138  C C   . SER A 1 435 ? 106.467 85.871  137.638 1.00 77.92  ? 434 SER A C   1 
ATOM   2139  O O   . SER A 1 435 ? 107.554 85.978  138.251 1.00 92.01  ? 434 SER A O   1 
ATOM   2140  C CB  . SER A 1 435 ? 106.852 83.949  136.309 1.00 66.61  ? 434 SER A CB  1 
ATOM   2141  O OG  . SER A 1 435 ? 108.122 83.697  136.914 1.00 82.03  ? 434 SER A OG  1 
ATOM   2142  N N   . LEU A 1 436 ? 105.249 86.115  138.166 1.00 65.27  ? 435 LEU A N   1 
ATOM   2143  C CA  . LEU A 1 436 ? 105.316 86.496  139.578 1.00 73.28  ? 435 LEU A CA  1 
ATOM   2144  C C   . LEU A 1 436 ? 105.425 85.288  140.481 1.00 70.23  ? 435 LEU A C   1 
ATOM   2145  O O   . LEU A 1 436 ? 105.704 85.543  141.662 1.00 95.95  ? 435 LEU A O   1 
ATOM   2146  C CB  . LEU A 1 436 ? 104.227 87.441  140.080 1.00 63.93  ? 435 LEU A CB  1 
ATOM   2147  C CG  . LEU A 1 436 ? 104.085 88.705  139.252 1.00 78.59  ? 435 LEU A CG  1 
ATOM   2148  C CD1 . LEU A 1 436 ? 103.150 89.638  139.971 1.00 115.66 ? 435 LEU A CD1 1 
ATOM   2149  C CD2 . LEU A 1 436 ? 105.377 89.422  138.980 1.00 84.82  ? 435 LEU A CD2 1 
ATOM   2150  N N   . SER A 1 437 ? 105.269 84.053  139.972 1.00 60.35  ? 436 SER A N   1 
ATOM   2151  C CA  . SER A 1 437 ? 105.567 82.945  140.857 1.00 71.37  ? 436 SER A CA  1 
ATOM   2152  C C   . SER A 1 437 ? 105.822 81.681  140.083 1.00 73.15  ? 436 SER A C   1 
ATOM   2153  O O   . SER A 1 437 ? 105.480 81.612  138.896 1.00 169.98 ? 436 SER A O   1 
ATOM   2154  C CB  . SER A 1 437 ? 104.430 82.749  141.849 1.00 94.59  ? 436 SER A CB  1 
ATOM   2155  O OG  . SER A 1 437 ? 104.668 81.650  142.736 1.00 133.71 ? 436 SER A OG  1 
ATOM   2156  N N   . GLN A 1 438 ? 106.378 80.671  140.775 1.00 78.76  ? 437 GLN A N   1 
ATOM   2157  C CA  . GLN A 1 438 ? 106.322 79.295  140.270 1.00 100.14 ? 437 GLN A CA  1 
ATOM   2158  C C   . GLN A 1 438 ? 104.908 78.672  140.160 1.00 105.60 ? 437 GLN A C   1 
ATOM   2159  O O   . GLN A 1 438 ? 104.724 77.719  139.380 1.00 139.91 ? 437 GLN A O   1 
ATOM   2160  C CB  . GLN A 1 438 ? 107.182 78.372  141.107 1.00 102.00 ? 437 GLN A CB  1 
ATOM   2161  C CG  . GLN A 1 438 ? 106.766 78.292  142.562 1.00 117.56 ? 437 GLN A CG  1 
ATOM   2162  C CD  . GLN A 1 438 ? 107.599 77.215  143.198 1.00 136.57 ? 437 GLN A CD  1 
ATOM   2163  O OE1 . GLN A 1 438 ? 108.576 76.708  142.634 1.00 71.34  ? 437 GLN A OE1 1 
ATOM   2164  N NE2 . GLN A 1 438 ? 107.192 76.866  144.406 1.00 176.30 ? 437 GLN A NE2 1 
ATOM   2165  N N   . ALA A 1 439 ? 103.901 79.170  140.880 1.00 90.80  ? 438 ALA A N   1 
ATOM   2166  C CA  . ALA A 1 439 ? 102.596 78.552  140.780 1.00 128.15 ? 438 ALA A CA  1 
ATOM   2167  C C   . ALA A 1 439 ? 101.422 79.514  140.934 1.00 103.51 ? 438 ALA A C   1 
ATOM   2168  O O   . ALA A 1 439 ? 100.505 79.451  140.123 1.00 194.76 ? 438 ALA A O   1 
ATOM   2169  C CB  . ALA A 1 439 ? 102.542 77.487  141.837 1.00 187.80 ? 438 ALA A CB  1 
ATOM   2170  N N   . ARG A 1 440 ? 101.403 80.346  141.976 1.00 97.89  ? 439 ARG A N   1 
ATOM   2171  C CA  . ARG A 1 440 ? 100.149 80.968  142.385 1.00 111.96 ? 439 ARG A CA  1 
ATOM   2172  C C   . ARG A 1 440 ? 99.855  82.126  141.429 1.00 100.28 ? 439 ARG A C   1 
ATOM   2173  O O   . ARG A 1 440 ? 100.753 82.583  140.720 1.00 79.10  ? 439 ARG A O   1 
ATOM   2174  C CB  . ARG A 1 440 ? 100.243 81.451  143.832 1.00 163.50 ? 439 ARG A CB  1 
ATOM   2175  C CG  . ARG A 1 440 ? 100.318 80.374  144.906 1.00 174.71 ? 439 ARG A CG  1 
ATOM   2176  C CD  . ARG A 1 440 ? 100.955 80.887  146.204 1.00 174.69 ? 439 ARG A CD  1 
ATOM   2177  N NE  . ARG A 1 440 ? 100.525 82.221  146.663 1.00 247.95 ? 439 ARG A NE  1 
ATOM   2178  C CZ  . ARG A 1 440 ? 101.151 82.951  147.596 1.00 331.41 ? 439 ARG A CZ  1 
ATOM   2179  N NH1 . ARG A 1 440 ? 100.654 84.118  147.996 1.00 321.93 ? 439 ARG A NH1 1 
ATOM   2180  N NH2 . ARG A 1 440 ? 102.276 82.512  148.139 1.00 363.18 ? 439 ARG A NH2 1 
ATOM   2181  N N   . LEU A 1 441 ? 98.592  82.601  141.392 1.00 111.06 ? 440 LEU A N   1 
ATOM   2182  C CA  . LEU A 1 441 ? 98.110  83.628  140.445 1.00 110.68 ? 440 LEU A CA  1 
ATOM   2183  C C   . LEU A 1 441 ? 98.802  84.994  140.557 1.00 106.90 ? 440 LEU A C   1 
ATOM   2184  O O   . LEU A 1 441 ? 99.345  85.287  141.623 1.00 107.17 ? 440 LEU A O   1 
ATOM   2185  C CB  . LEU A 1 441 ? 96.650  83.857  140.791 1.00 103.19 ? 440 LEU A CB  1 
ATOM   2186  C CG  . LEU A 1 441 ? 95.720  82.705  140.578 1.00 113.18 ? 440 LEU A CG  1 
ATOM   2187  C CD1 . LEU A 1 441 ? 94.443  83.023  141.320 1.00 214.25 ? 440 LEU A CD1 1 
ATOM   2188  C CD2 . LEU A 1 441 ? 95.463  82.583  139.091 1.00 149.82 ? 440 LEU A CD2 1 
ATOM   2189  N N   . LEU A 1 442 ? 98.755  85.856  139.517 1.00 93.68  ? 441 LEU A N   1 
ATOM   2190  C CA  . LEU A 1 442 ? 99.133  87.264  139.684 1.00 85.11  ? 441 LEU A CA  1 
ATOM   2191  C C   . LEU A 1 442 ? 98.454  87.879  140.882 1.00 90.60  ? 441 LEU A C   1 
ATOM   2192  O O   . LEU A 1 442 ? 99.103  88.558  141.689 1.00 125.63 ? 441 LEU A O   1 
ATOM   2193  C CB  . LEU A 1 442 ? 98.724  88.142  138.509 1.00 75.40  ? 441 LEU A CB  1 
ATOM   2194  C CG  . LEU A 1 442 ? 99.630  88.025  137.282 1.00 91.93  ? 441 LEU A CG  1 
ATOM   2195  C CD1 . LEU A 1 442 ? 99.477  89.196  136.296 1.00 96.62  ? 441 LEU A CD1 1 
ATOM   2196  C CD2 . LEU A 1 442 ? 101.099 88.029  137.630 1.00 84.38  ? 441 LEU A CD2 1 
ATOM   2197  N N   . THR A 1 443 ? 97.142  87.632  140.955 1.00 79.72  ? 442 THR A N   1 
ATOM   2198  C CA  . THR A 1 443 ? 96.346  88.284  141.973 1.00 85.81  ? 442 THR A CA  1 
ATOM   2199  C C   . THR A 1 443 ? 96.673  87.800  143.386 1.00 82.81  ? 442 THR A C   1 
ATOM   2200  O O   . THR A 1 443 ? 96.119  88.324  144.345 1.00 109.84 ? 442 THR A O   1 
ATOM   2201  C CB  . THR A 1 443 ? 94.869  88.205  141.609 1.00 131.18 ? 442 THR A CB  1 
ATOM   2202  O OG1 . THR A 1 443 ? 94.712  88.202  140.184 1.00 123.00 ? 442 THR A OG1 1 
ATOM   2203  C CG2 . THR A 1 443 ? 94.126  89.398  142.181 1.00 249.82 ? 442 THR A CG2 1 
ATOM   2204  N N   . SER A 1 444 ? 97.588  86.841  143.536 1.00 90.62  ? 443 SER A N   1 
ATOM   2205  C CA  . SER A 1 444 ? 98.076  86.452  144.847 1.00 124.94 ? 443 SER A CA  1 
ATOM   2206  C C   . SER A 1 444 ? 98.999  87.503  145.456 1.00 101.62 ? 443 SER A C   1 
ATOM   2207  O O   . SER A 1 444 ? 99.281  87.437  146.661 1.00 128.84 ? 443 SER A O   1 
ATOM   2208  C CB  . SER A 1 444 ? 98.741  85.091  144.801 1.00 141.10 ? 443 SER A CB  1 
ATOM   2209  O OG  . SER A 1 444 ? 98.622  84.446  146.060 1.00 207.04 ? 443 SER A OG  1 
ATOM   2210  N N   . PHE A 1 445 ? 99.471  88.434  144.625 1.00 100.58 ? 444 PHE A N   1 
ATOM   2211  C CA  . PHE A 1 445 ? 100.560 89.332  144.995 1.00 111.87 ? 444 PHE A CA  1 
ATOM   2212  C C   . PHE A 1 445 ? 100.157 90.754  144.689 1.00 90.22  ? 444 PHE A C   1 
ATOM   2213  O O   . PHE A 1 445 ? 100.271 91.622  145.558 1.00 128.13 ? 444 PHE A O   1 
ATOM   2214  C CB  . PHE A 1 445 ? 101.879 88.997  144.272 1.00 104.58 ? 444 PHE A CB  1 
ATOM   2215  C CG  . PHE A 1 445 ? 102.260 87.538  144.391 1.00 111.99 ? 444 PHE A CG  1 
ATOM   2216  C CD1 . PHE A 1 445 ? 102.749 86.992  145.568 1.00 142.15 ? 444 PHE A CD1 1 
ATOM   2217  C CD2 . PHE A 1 445 ? 102.087 86.692  143.327 1.00 118.52 ? 444 PHE A CD2 1 
ATOM   2218  C CE1 . PHE A 1 445 ? 103.095 85.655  145.667 1.00 159.39 ? 444 PHE A CE1 1 
ATOM   2219  C CE2 . PHE A 1 445 ? 102.429 85.351  143.419 1.00 150.69 ? 444 PHE A CE2 1 
ATOM   2220  C CZ  . PHE A 1 445 ? 102.923 84.823  144.592 1.00 181.43 ? 444 PHE A CZ  1 
ATOM   2221  N N   . LEU A 1 446 ? 99.700  90.962  143.454 1.00 76.00  ? 445 LEU A N   1 
ATOM   2222  C CA  . LEU A 1 446 ? 99.333  92.291  143.012 1.00 92.95  ? 445 LEU A CA  1 
ATOM   2223  C C   . LEU A 1 446 ? 97.978  92.730  143.564 1.00 129.13 ? 445 LEU A C   1 
ATOM   2224  O O   . LEU A 1 446 ? 97.001  91.969  143.604 1.00 148.37 ? 445 LEU A O   1 
ATOM   2225  C CB  . LEU A 1 446 ? 99.339  92.323  141.484 1.00 87.28  ? 445 LEU A CB  1 
ATOM   2226  C CG  . LEU A 1 446 ? 100.729 92.115  140.872 1.00 88.99  ? 445 LEU A CG  1 
ATOM   2227  C CD1 . LEU A 1 446 ? 100.695 92.423  139.445 1.00 82.97  ? 445 LEU A CD1 1 
ATOM   2228  C CD2 . LEU A 1 446 ? 101.847 92.960  141.476 1.00 83.37  ? 445 LEU A CD2 1 
ATOM   2229  N N   . PRO A 1 447 ? 97.881  94.011  144.000 1.00 110.33 ? 446 PRO A N   1 
ATOM   2230  C CA  . PRO A 1 447 ? 96.589  94.609  144.280 1.00 127.20 ? 446 PRO A CA  1 
ATOM   2231  C C   . PRO A 1 447 ? 96.003  95.014  142.944 1.00 122.98 ? 446 PRO A C   1 
ATOM   2232  O O   . PRO A 1 447 ? 96.756  95.383  142.033 1.00 132.32 ? 446 PRO A O   1 
ATOM   2233  C CB  . PRO A 1 447 ? 96.973  95.791  145.184 1.00 178.80 ? 446 PRO A CB  1 
ATOM   2234  C CG  . PRO A 1 447 ? 98.356  96.216  144.723 1.00 134.22 ? 446 PRO A CG  1 
ATOM   2235  C CD  . PRO A 1 447 ? 98.999  94.932  144.263 1.00 107.96 ? 446 PRO A CD  1 
ATOM   2236  N N   . ALA A 1 448 ? 94.672  94.964  142.850 1.00 114.97 ? 447 ALA A N   1 
ATOM   2237  C CA  . ALA A 1 448 ? 94.037  94.918  141.548 1.00 131.24 ? 447 ALA A CA  1 
ATOM   2238  C C   . ALA A 1 448 ? 94.234  96.163  140.658 1.00 112.41 ? 447 ALA A C   1 
ATOM   2239  O O   . ALA A 1 448 ? 93.916  96.021  139.467 1.00 112.25 ? 447 ALA A O   1 
ATOM   2240  C CB  . ALA A 1 448 ? 92.585  94.627  141.786 1.00 186.32 ? 447 ALA A CB  1 
ATOM   2241  N N   . GLN A 1 449 ? 94.718  97.333  141.174 1.00 117.54 ? 448 GLN A N   1 
ATOM   2242  C CA  . GLN A 1 449 ? 95.072  98.484  140.322 1.00 142.32 ? 448 GLN A CA  1 
ATOM   2243  C C   . GLN A 1 449 ? 96.309  98.259  139.438 1.00 120.46 ? 448 GLN A C   1 
ATOM   2244  O O   . GLN A 1 449 ? 96.447  98.882  138.369 1.00 120.42 ? 448 GLN A O   1 
ATOM   2245  C CB  . GLN A 1 449 ? 95.305  99.798  141.069 1.00 151.20 ? 448 GLN A CB  1 
ATOM   2246  C CG  . GLN A 1 449 ? 96.544  99.903  141.969 1.00 165.44 ? 448 GLN A CG  1 
ATOM   2247  C CD  . GLN A 1 449 ? 96.170  99.493  143.387 1.00 205.72 ? 448 GLN A CD  1 
ATOM   2248  O OE1 . GLN A 1 449 ? 95.410  98.541  143.595 1.00 184.79 ? 448 GLN A OE1 1 
ATOM   2249  N NE2 . GLN A 1 449 ? 96.683  100.202 144.395 1.00 194.27 ? 448 GLN A NE2 1 
ATOM   2250  N N   . LEU A 1 450 ? 97.191  97.357  139.857 1.00 89.85  ? 449 LEU A N   1 
ATOM   2251  C CA  . LEU A 1 450 ? 98.359  97.024  139.060 1.00 90.55  ? 449 LEU A CA  1 
ATOM   2252  C C   . LEU A 1 450 ? 98.175  95.915  138.033 1.00 92.11  ? 449 LEU A C   1 
ATOM   2253  O O   . LEU A 1 450 ? 99.063  95.794  137.184 1.00 75.21  ? 449 LEU A O   1 
ATOM   2254  C CB  . LEU A 1 450 ? 99.428  96.531  140.017 1.00 78.35  ? 449 LEU A CB  1 
ATOM   2255  C CG  . LEU A 1 450 ? 99.923  97.583  140.964 1.00 97.09  ? 449 LEU A CG  1 
ATOM   2256  C CD1 . LEU A 1 450 ? 101.102 96.990  141.674 1.00 103.59 ? 449 LEU A CD1 1 
ATOM   2257  C CD2 . LEU A 1 450 ? 100.302 98.895  140.237 1.00 114.39 ? 449 LEU A CD2 1 
ATOM   2258  N N   . LEU A 1 451 ? 97.116  95.086  138.125 1.00 89.70  ? 450 LEU A N   1 
ATOM   2259  C CA  . LEU A 1 451 ? 97.079  93.931  137.249 1.00 79.59  ? 450 LEU A CA  1 
ATOM   2260  C C   . LEU A 1 451 ? 97.246  94.384  135.814 1.00 72.89  ? 450 LEU A C   1 
ATOM   2261  O O   . LEU A 1 451 ? 97.971  93.677  135.108 1.00 70.78  ? 450 LEU A O   1 
ATOM   2262  C CB  . LEU A 1 451 ? 95.793  93.157  137.401 1.00 68.21  ? 450 LEU A CB  1 
ATOM   2263  C CG  . LEU A 1 451 ? 95.782  92.351  138.671 1.00 94.10  ? 450 LEU A CG  1 
ATOM   2264  C CD1 . LEU A 1 451 ? 94.362  91.902  138.981 1.00 186.70 ? 450 LEU A CD1 1 
ATOM   2265  C CD2 . LEU A 1 451 ? 96.618  91.107  138.534 1.00 131.64 ? 450 LEU A CD2 1 
ATOM   2266  N N   . ARG A 1 452 ? 96.609  95.516  135.417 1.00 60.97  ? 451 ARG A N   1 
ATOM   2267  C CA  . ARG A 1 452 ? 96.718  95.895  134.020 1.00 72.29  ? 451 ARG A CA  1 
ATOM   2268  C C   . ARG A 1 452 ? 98.143  96.320  133.644 1.00 60.22  ? 451 ARG A C   1 
ATOM   2269  O O   . ARG A 1 452 ? 98.695  96.040  132.561 1.00 46.38  ? 451 ARG A O   1 
ATOM   2270  C CB  . ARG A 1 452 ? 95.704  96.956  133.688 1.00 106.99 ? 451 ARG A CB  1 
ATOM   2271  C CG  . ARG A 1 452 ? 94.289  96.432  133.499 1.00 124.37 ? 451 ARG A CG  1 
ATOM   2272  C CD  . ARG A 1 452 ? 93.550  97.534  132.773 1.00 103.10 ? 451 ARG A CD  1 
ATOM   2273  N NE  . ARG A 1 452 ? 92.203  97.177  132.984 1.00 130.70 ? 451 ARG A NE  1 
ATOM   2274  C CZ  . ARG A 1 452 ? 91.405  96.970  131.996 1.00 193.49 ? 451 ARG A CZ  1 
ATOM   2275  N NH1 . ARG A 1 452 ? 90.142  96.703  132.281 1.00 284.86 ? 451 ARG A NH1 1 
ATOM   2276  N NH2 . ARG A 1 452 ? 91.890  97.048  130.764 1.00 138.33 ? 451 ARG A NH2 1 
ATOM   2277  N N   . LEU A 1 453 ? 98.743  96.967  134.605 1.00 67.54  ? 452 LEU A N   1 
ATOM   2278  C CA  . LEU A 1 453 ? 100.060 97.516  134.398 1.00 60.72  ? 452 LEU A CA  1 
ATOM   2279  C C   . LEU A 1 453 ? 101.104 96.433  134.336 1.00 58.06  ? 452 LEU A C   1 
ATOM   2280  O O   . LEU A 1 453 ? 102.077 96.670  133.668 1.00 46.85  ? 452 LEU A O   1 
ATOM   2281  C CB  . LEU A 1 453 ? 100.372 98.369  135.614 1.00 69.08  ? 452 LEU A CB  1 
ATOM   2282  C CG  . LEU A 1 453 ? 101.470 99.378  135.431 1.00 75.98  ? 452 LEU A CG  1 
ATOM   2283  C CD1 . LEU A 1 453 ? 101.277 100.192 134.188 1.00 88.70  ? 452 LEU A CD1 1 
ATOM   2284  C CD2 . LEU A 1 453 ? 101.440 100.298 136.607 1.00 107.98 ? 452 LEU A CD2 1 
ATOM   2285  N N   . TYR A 1 454 ? 100.904 95.301  135.043 1.00 62.12  ? 453 TYR A N   1 
ATOM   2286  C CA  . TYR A 1 454 ? 101.852 94.209  134.968 1.00 62.91  ? 453 TYR A CA  1 
ATOM   2287  C C   . TYR A 1 454 ? 101.621 93.391  133.719 1.00 65.70  ? 453 TYR A C   1 
ATOM   2288  O O   . TYR A 1 454 ? 102.574 92.942  133.109 1.00 96.88  ? 453 TYR A O   1 
ATOM   2289  C CB  . TYR A 1 454 ? 101.803 93.226  136.100 1.00 72.36  ? 453 TYR A CB  1 
ATOM   2290  C CG  . TYR A 1 454 ? 102.816 93.630  137.163 1.00 66.91  ? 453 TYR A CG  1 
ATOM   2291  C CD1 . TYR A 1 454 ? 102.701 94.756  137.899 1.00 60.93  ? 453 TYR A CD1 1 
ATOM   2292  C CD2 . TYR A 1 454 ? 103.861 92.823  137.433 1.00 76.04  ? 453 TYR A CD2 1 
ATOM   2293  C CE1 . TYR A 1 454 ? 103.614 95.052  138.869 1.00 75.76  ? 453 TYR A CE1 1 
ATOM   2294  C CE2 . TYR A 1 454 ? 104.790 93.105  138.390 1.00 84.56  ? 453 TYR A CE2 1 
ATOM   2295  C CZ  . TYR A 1 454 ? 104.676 94.225  139.122 1.00 87.29  ? 453 TYR A CZ  1 
ATOM   2296  O OH  . TYR A 1 454 ? 105.708 94.352  140.017 1.00 130.15 ? 453 TYR A OH  1 
ATOM   2297  N N   . GLN A 1 455 ? 100.403 93.239  133.277 1.00 70.34  ? 454 GLN A N   1 
ATOM   2298  C CA  . GLN A 1 455 ? 100.231 92.559  132.000 1.00 74.87  ? 454 GLN A CA  1 
ATOM   2299  C C   . GLN A 1 455 ? 100.909 93.334  130.912 1.00 64.33  ? 454 GLN A C   1 
ATOM   2300  O O   . GLN A 1 455 ? 101.323 92.682  129.966 1.00 101.49 ? 454 GLN A O   1 
ATOM   2301  C CB  . GLN A 1 455 ? 98.754  92.280  131.601 1.00 72.36  ? 454 GLN A CB  1 
ATOM   2302  C CG  . GLN A 1 455 ? 98.432  91.112  132.519 1.00 119.32 ? 454 GLN A CG  1 
ATOM   2303  C CD  . GLN A 1 455 ? 97.079  90.534  132.434 1.00 124.69 ? 454 GLN A CD  1 
ATOM   2304  O OE1 . GLN A 1 455 ? 96.374  90.870  131.486 1.00 125.76 ? 454 GLN A OE1 1 
ATOM   2305  N NE2 . GLN A 1 455 ? 96.793  89.686  133.427 1.00 112.66 ? 454 GLN A NE2 1 
ATOM   2306  N N   . LEU A 1 456 ? 100.948 94.665  130.994 1.00 46.90  ? 455 LEU A N   1 
ATOM   2307  C CA  . LEU A 1 456 ? 101.601 95.385  129.936 1.00 54.11  ? 455 LEU A CA  1 
ATOM   2308  C C   . LEU A 1 456 ? 103.121 95.160  129.994 1.00 49.43  ? 455 LEU A C   1 
ATOM   2309  O O   . LEU A 1 456 ? 103.815 95.311  129.004 1.00 48.44  ? 455 LEU A O   1 
ATOM   2310  C CB  . LEU A 1 456 ? 101.165 96.843  129.999 1.00 65.09  ? 455 LEU A CB  1 
ATOM   2311  C CG  . LEU A 1 456 ? 101.905 97.781  129.039 1.00 89.26  ? 455 LEU A CG  1 
ATOM   2312  C CD1 . LEU A 1 456 ? 101.860 97.318  127.585 1.00 71.22  ? 455 LEU A CD1 1 
ATOM   2313  C CD2 . LEU A 1 456 ? 101.328 99.186  129.156 1.00 106.57 ? 455 LEU A CD2 1 
ATOM   2314  N N   . MET A 1 457 ? 103.652 94.827  131.149 1.00 53.34  ? 456 MET A N   1 
ATOM   2315  C CA  . MET A 1 457 ? 105.080 94.727  131.351 1.00 49.26  ? 456 MET A CA  1 
ATOM   2316  C C   . MET A 1 457 ? 105.507 93.289  131.105 1.00 56.73  ? 456 MET A C   1 
ATOM   2317  O O   . MET A 1 457 ? 106.413 93.099  130.339 1.00 105.66 ? 456 MET A O   1 
ATOM   2318  C CB  . MET A 1 457 ? 105.418 95.146  132.783 1.00 53.72  ? 456 MET A CB  1 
ATOM   2319  C CG  . MET A 1 457 ? 106.826 95.010  133.077 1.00 67.06  ? 456 MET A CG  1 
ATOM   2320  S SD  . MET A 1 457 ? 107.258 95.295  134.700 1.00 63.49  ? 456 MET A SD  1 
ATOM   2321  C CE  . MET A 1 457 ? 106.899 93.690  135.396 1.00 54.26  ? 456 MET A CE  1 
ATOM   2322  N N   . LEU A 1 458 ? 104.877 92.292  131.714 1.00 57.62  ? 457 LEU A N   1 
ATOM   2323  C CA  . LEU A 1 458 ? 105.155 90.914  131.440 1.00 53.37  ? 457 LEU A CA  1 
ATOM   2324  C C   . LEU A 1 458 ? 105.085 90.587  129.928 1.00 83.67  ? 457 LEU A C   1 
ATOM   2325  O O   . LEU A 1 458 ? 105.856 89.699  129.404 1.00 60.46  ? 457 LEU A O   1 
ATOM   2326  C CB  . LEU A 1 458 ? 104.220 90.107  132.362 1.00 58.02  ? 457 LEU A CB  1 
ATOM   2327  C CG  . LEU A 1 458 ? 105.026 89.335  133.456 1.00 88.20  ? 457 LEU A CG  1 
ATOM   2328  C CD1 . LEU A 1 458 ? 106.040 90.168  134.249 1.00 86.98  ? 457 LEU A CD1 1 
ATOM   2329  C CD2 . LEU A 1 458 ? 104.123 88.623  134.454 1.00 97.22  ? 457 LEU A CD2 1 
ATOM   2330  N N   . PHE A 1 459 ? 104.213 91.288  129.180 1.00 66.15  ? 458 PHE A N   1 
ATOM   2331  C CA  . PHE A 1 459 ? 104.198 91.022  127.748 1.00 81.24  ? 458 PHE A CA  1 
ATOM   2332  C C   . PHE A 1 459 ? 105.312 91.684  126.941 1.00 55.33  ? 458 PHE A C   1 
ATOM   2333  O O   . PHE A 1 459 ? 105.380 91.429  125.756 1.00 102.70 ? 458 PHE A O   1 
ATOM   2334  C CB  . PHE A 1 459 ? 102.778 91.236  127.185 1.00 77.88  ? 458 PHE A CB  1 
ATOM   2335  C CG  . PHE A 1 459 ? 101.992 89.928  127.225 1.00 66.08  ? 458 PHE A CG  1 
ATOM   2336  C CD1 . PHE A 1 459 ? 102.305 88.862  126.439 1.00 74.19  ? 458 PHE A CD1 1 
ATOM   2337  C CD2 . PHE A 1 459 ? 100.985 89.718  128.109 1.00 70.15  ? 458 PHE A CD2 1 
ATOM   2338  C CE1 . PHE A 1 459 ? 101.602 87.690  126.501 1.00 109.61 ? 458 PHE A CE1 1 
ATOM   2339  C CE2 . PHE A 1 459 ? 100.282 88.544  128.194 1.00 63.65  ? 458 PHE A CE2 1 
ATOM   2340  C CZ  . PHE A 1 459 ? 100.591 87.542  127.391 1.00 95.71  ? 458 PHE A CZ  1 
ATOM   2341  N N   . THR A 1 460 ? 106.168 92.490  127.520 1.00 76.92  ? 459 THR A N   1 
ATOM   2342  C CA  . THR A 1 460 ? 107.065 93.319  126.732 1.00 74.80  ? 459 THR A CA  1 
ATOM   2343  C C   . THR A 1 460 ? 108.508 93.440  127.257 1.00 64.10  ? 459 THR A C   1 
ATOM   2344  O O   . THR A 1 460 ? 109.305 94.123  126.642 1.00 96.24  ? 459 THR A O   1 
ATOM   2345  C CB  . THR A 1 460 ? 106.417 94.703  126.585 1.00 71.36  ? 459 THR A CB  1 
ATOM   2346  O OG1 . THR A 1 460 ? 106.570 95.397  127.801 1.00 56.88  ? 459 THR A OG1 1 
ATOM   2347  C CG2 . THR A 1 460 ? 104.941 94.710  126.273 1.00 72.05  ? 459 THR A CG2 1 
ATOM   2348  N N   . LEU A 1 461 ? 108.873 92.777  128.333 1.00 70.13  ? 460 LEU A N   1 
ATOM   2349  C CA  . LEU A 1 461 ? 110.258 92.552  128.668 1.00 68.18  ? 460 LEU A CA  1 
ATOM   2350  C C   . LEU A 1 461 ? 110.804 91.377  127.856 1.00 74.81  ? 460 LEU A C   1 
ATOM   2351  O O   . LEU A 1 461 ? 110.027 90.503  127.433 1.00 67.67  ? 460 LEU A O   1 
ATOM   2352  C CB  . LEU A 1 461 ? 110.371 92.157  130.131 1.00 74.15  ? 460 LEU A CB  1 
ATOM   2353  C CG  . LEU A 1 461 ? 109.800 93.182  131.058 1.00 69.46  ? 460 LEU A CG  1 
ATOM   2354  C CD1 . LEU A 1 461 ? 109.791 92.615  132.471 1.00 68.81  ? 460 LEU A CD1 1 
ATOM   2355  C CD2 . LEU A 1 461 ? 110.586 94.479  130.859 1.00 73.99  ? 460 LEU A CD2 1 
ATOM   2356  N N   . PRO A 1 462 ? 112.145 91.386  127.667 1.00 54.07  ? 461 PRO A N   1 
ATOM   2357  C CA  . PRO A 1 462 ? 112.852 90.282  127.013 1.00 67.62  ? 461 PRO A CA  1 
ATOM   2358  C C   . PRO A 1 462 ? 112.720 88.939  127.659 1.00 59.30  ? 461 PRO A C   1 
ATOM   2359  O O   . PRO A 1 462 ? 113.230 88.827  128.744 1.00 99.15  ? 461 PRO A O   1 
ATOM   2360  C CB  . PRO A 1 462 ? 114.301 90.629  127.318 1.00 89.64  ? 461 PRO A CB  1 
ATOM   2361  C CG  . PRO A 1 462 ? 114.252 92.176  127.483 1.00 61.91  ? 461 PRO A CG  1 
ATOM   2362  C CD  . PRO A 1 462 ? 112.977 92.534  128.074 1.00 36.53  ? 461 PRO A CD  1 
ATOM   2363  N N   . GLY A 1 463 ? 112.064 87.956  127.042 1.00 72.69  ? 462 GLY A N   1 
ATOM   2364  C CA  . GLY A 1 463 ? 111.821 86.680  127.728 1.00 68.07  ? 462 GLY A CA  1 
ATOM   2365  C C   . GLY A 1 463 ? 110.413 86.138  127.657 1.00 48.10  ? 462 GLY A C   1 
ATOM   2366  O O   . GLY A 1 463 ? 109.526 86.809  127.198 1.00 117.51 ? 462 GLY A O   1 
ATOM   2367  N N   . THR A 1 464 ? 110.231 84.944  128.101 1.00 49.32  ? 463 THR A N   1 
ATOM   2368  C CA  . THR A 1 464 ? 109.018 84.204  127.874 1.00 58.28  ? 463 THR A CA  1 
ATOM   2369  C C   . THR A 1 464 ? 108.091 84.361  129.063 1.00 45.18  ? 463 THR A C   1 
ATOM   2370  O O   . THR A 1 464 ? 108.289 83.734  130.106 1.00 36.99  ? 463 THR A O   1 
ATOM   2371  C CB  . THR A 1 464 ? 109.415 82.721  127.919 1.00 76.90  ? 463 THR A CB  1 
ATOM   2372  O OG1 . THR A 1 464 ? 110.169 82.562  126.724 1.00 80.33  ? 463 THR A OG1 1 
ATOM   2373  C CG2 . THR A 1 464 ? 108.265 81.748  128.080 1.00 59.28  ? 463 THR A CG2 1 
ATOM   2374  N N   . PRO A 1 465 ? 107.043 85.151  129.011 1.00 38.70  ? 464 PRO A N   1 
ATOM   2375  C CA  . PRO A 1 465 ? 106.206 85.304  130.185 1.00 41.40  ? 464 PRO A CA  1 
ATOM   2376  C C   . PRO A 1 465 ? 105.477 84.061  130.571 1.00 36.32  ? 464 PRO A C   1 
ATOM   2377  O O   . PRO A 1 465 ? 105.107 83.291  129.738 1.00 53.68  ? 464 PRO A O   1 
ATOM   2378  C CB  . PRO A 1 465 ? 105.079 86.293  129.716 1.00 55.05  ? 464 PRO A CB  1 
ATOM   2379  C CG  . PRO A 1 465 ? 105.082 86.345  128.268 1.00 53.41  ? 464 PRO A CG  1 
ATOM   2380  C CD  . PRO A 1 465 ? 106.545 85.942  127.885 1.00 48.38  ? 464 PRO A CD  1 
ATOM   2381  N N   . VAL A 1 466 ? 105.170 83.924  131.821 1.00 44.30  ? 465 VAL A N   1 
ATOM   2382  C CA  . VAL A 1 466 ? 104.428 82.773  132.269 1.00 56.93  ? 465 VAL A CA  1 
ATOM   2383  C C   . VAL A 1 466 ? 103.272 83.237  133.179 1.00 56.38  ? 465 VAL A C   1 
ATOM   2384  O O   . VAL A 1 466 ? 103.430 83.955  134.153 1.00 97.05  ? 465 VAL A O   1 
ATOM   2385  C CB  . VAL A 1 466 ? 105.388 81.809  132.999 1.00 40.98  ? 465 VAL A CB  1 
ATOM   2386  C CG1 . VAL A 1 466 ? 104.575 80.756  133.762 1.00 50.33  ? 465 VAL A CG1 1 
ATOM   2387  C CG2 . VAL A 1 466 ? 106.434 81.233  132.084 1.00 29.26  ? 465 VAL A CG2 1 
ATOM   2388  N N   . PHE A 1 467 ? 102.112 82.761  132.855 1.00 50.56  ? 466 PHE A N   1 
ATOM   2389  C CA  . PHE A 1 467 ? 100.936 82.993  133.624 1.00 65.00  ? 466 PHE A CA  1 
ATOM   2390  C C   . PHE A 1 467 ? 100.344 81.701  134.158 1.00 61.41  ? 466 PHE A C   1 
ATOM   2391  O O   . PHE A 1 467 ? 100.417 80.698  133.480 1.00 60.85  ? 466 PHE A O   1 
ATOM   2392  C CB  . PHE A 1 467 ? 99.947  83.680  132.688 1.00 56.19  ? 466 PHE A CB  1 
ATOM   2393  C CG  . PHE A 1 467 ? 100.502 84.955  132.119 1.00 55.93  ? 466 PHE A CG  1 
ATOM   2394  C CD1 . PHE A 1 467 ? 100.473 86.083  132.851 1.00 62.55  ? 466 PHE A CD1 1 
ATOM   2395  C CD2 . PHE A 1 467 ? 101.041 85.044  130.863 1.00 92.94  ? 466 PHE A CD2 1 
ATOM   2396  C CE1 . PHE A 1 467 ? 100.924 87.291  132.375 1.00 78.12  ? 466 PHE A CE1 1 
ATOM   2397  C CE2 . PHE A 1 467 ? 101.493 86.251  130.364 1.00 77.11  ? 466 PHE A CE2 1 
ATOM   2398  C CZ  . PHE A 1 467 ? 101.433 87.371  131.129 1.00 97.18  ? 466 PHE A CZ  1 
ATOM   2399  N N   . SER A 1 468 ? 99.688  81.772  135.336 1.00 62.43  ? 467 SER A N   1 
ATOM   2400  C CA  . SER A 1 468 ? 98.742  80.729  135.738 1.00 69.67  ? 467 SER A CA  1 
ATOM   2401  C C   . SER A 1 468 ? 97.361  81.018  135.174 1.00 64.60  ? 467 SER A C   1 
ATOM   2402  O O   . SER A 1 468 ? 97.096  82.083  134.607 1.00 84.17  ? 467 SER A O   1 
ATOM   2403  C CB  . SER A 1 468 ? 98.690  80.485  137.206 1.00 74.64  ? 467 SER A CB  1 
ATOM   2404  O OG  . SER A 1 468 ? 100.061 80.434  137.723 1.00 199.12 ? 467 SER A OG  1 
ATOM   2405  N N   . TYR A 1 469 ? 96.456  80.070  135.362 1.00 64.34  ? 468 TYR A N   1 
ATOM   2406  C CA  . TYR A 1 469 ? 95.218  80.127  134.595 1.00 59.46  ? 468 TYR A CA  1 
ATOM   2407  C C   . TYR A 1 469 ? 94.329  81.140  135.268 1.00 65.47  ? 468 TYR A C   1 
ATOM   2408  O O   . TYR A 1 469 ? 94.241  81.224  136.490 1.00 46.28  ? 468 TYR A O   1 
ATOM   2409  C CB  . TYR A 1 469 ? 94.366  78.869  134.531 1.00 69.72  ? 468 TYR A CB  1 
ATOM   2410  C CG  . TYR A 1 469 ? 94.001  78.288  135.881 1.00 63.02  ? 468 TYR A CG  1 
ATOM   2411  C CD1 . TYR A 1 469 ? 94.887  77.614  136.707 1.00 81.57  ? 468 TYR A CD1 1 
ATOM   2412  C CD2 . TYR A 1 469 ? 92.747  78.445  136.282 1.00 61.77  ? 468 TYR A CD2 1 
ATOM   2413  C CE1 . TYR A 1 469 ? 94.513  77.126  137.915 1.00 99.97  ? 468 TYR A CE1 1 
ATOM   2414  C CE2 . TYR A 1 469 ? 92.352  77.948  137.498 1.00 112.60 ? 468 TYR A CE2 1 
ATOM   2415  C CZ  . TYR A 1 469 ? 93.231  77.283  138.326 1.00 103.73 ? 468 TYR A CZ  1 
ATOM   2416  O OH  . TYR A 1 469 ? 92.883  76.769  139.539 1.00 99.29  ? 468 TYR A OH  1 
ATOM   2417  N N   . GLY A 1 470 ? 93.727  81.953  134.432 1.00 83.07  ? 469 GLY A N   1 
ATOM   2418  C CA  . GLY A 1 470 ? 92.863  82.961  134.982 1.00 82.82  ? 469 GLY A CA  1 
ATOM   2419  C C   . GLY A 1 470 ? 93.570  84.243  135.334 1.00 62.12  ? 469 GLY A C   1 
ATOM   2420  O O   . GLY A 1 470 ? 92.879  85.169  135.668 1.00 108.03 ? 469 GLY A O   1 
ATOM   2421  N N   . ASP A 1 471 ? 94.884  84.334  135.216 1.00 82.99  ? 470 ASP A N   1 
ATOM   2422  C CA  . ASP A 1 471 ? 95.590  85.611  135.209 1.00 94.75  ? 470 ASP A CA  1 
ATOM   2423  C C   . ASP A 1 471 ? 95.001  86.503  134.139 1.00 66.72  ? 470 ASP A C   1 
ATOM   2424  O O   . ASP A 1 471 ? 94.926  87.705  134.343 1.00 118.15 ? 470 ASP A O   1 
ATOM   2425  C CB  . ASP A 1 471 ? 97.107  85.448  135.051 1.00 96.17  ? 470 ASP A CB  1 
ATOM   2426  C CG  . ASP A 1 471 ? 97.743  84.828  136.311 1.00 171.55 ? 470 ASP A CG  1 
ATOM   2427  O OD1 . ASP A 1 471 ? 97.142  84.922  137.435 1.00 175.90 ? 470 ASP A OD1 1 
ATOM   2428  O OD2 . ASP A 1 471 ? 98.835  84.220  136.207 1.00 160.34 ? 470 ASP A OD2 1 
ATOM   2429  N N   . GLU A 1 472 ? 94.540  85.907  133.046 1.00 67.25  ? 471 GLU A N   1 
ATOM   2430  C CA  . GLU A 1 472 ? 94.133  86.662  131.869 1.00 90.34  ? 471 GLU A CA  1 
ATOM   2431  C C   . GLU A 1 472 ? 92.797  87.320  132.165 1.00 89.89  ? 471 GLU A C   1 
ATOM   2432  O O   . GLU A 1 472 ? 92.424  88.197  131.400 1.00 71.82  ? 471 GLU A O   1 
ATOM   2433  C CB  . GLU A 1 472 ? 94.166  85.796  130.588 1.00 92.00  ? 471 GLU A CB  1 
ATOM   2434  C CG  . GLU A 1 472 ? 93.075  84.716  130.565 1.00 95.00  ? 471 GLU A CG  1 
ATOM   2435  C CD  . GLU A 1 472 ? 93.221  83.468  131.425 1.00 138.55 ? 471 GLU A CD  1 
ATOM   2436  O OE1 . GLU A 1 472 ? 94.071  83.454  132.283 1.00 172.89 ? 471 GLU A OE1 1 
ATOM   2437  O OE2 . GLU A 1 472 ? 92.509  82.498  131.218 1.00 168.67 ? 471 GLU A OE2 1 
ATOM   2438  N N   . ILE A 1 473 ? 92.103  86.889  133.239 1.00 93.98  ? 472 ILE A N   1 
ATOM   2439  C CA  . ILE A 1 473 ? 90.835  87.491  133.625 1.00 99.65  ? 472 ILE A CA  1 
ATOM   2440  C C   . ILE A 1 473 ? 90.882  88.113  134.995 1.00 74.96  ? 472 ILE A C   1 
ATOM   2441  O O   . ILE A 1 473 ? 89.827  88.516  135.477 1.00 118.65 ? 472 ILE A O   1 
ATOM   2442  C CB  . ILE A 1 473 ? 89.691  86.463  133.614 1.00 94.31  ? 472 ILE A CB  1 
ATOM   2443  C CG1 . ILE A 1 473 ? 89.851  85.425  134.723 1.00 100.60 ? 472 ILE A CG1 1 
ATOM   2444  C CG2 . ILE A 1 473 ? 89.586  85.886  132.222 1.00 107.90 ? 472 ILE A CG2 1 
ATOM   2445  C CD1 . ILE A 1 473 ? 88.688  84.544  134.961 1.00 99.97  ? 472 ILE A CD1 1 
ATOM   2446  N N   . GLY A 1 474 ? 92.060  88.182  135.608 1.00 87.84  ? 473 GLY A N   1 
ATOM   2447  C CA  . GLY A 1 474 ? 92.207  88.683  136.969 1.00 106.39 ? 473 GLY A CA  1 
ATOM   2448  C C   . GLY A 1 474 ? 91.385  87.897  137.987 1.00 92.54  ? 473 GLY A C   1 
ATOM   2449  O O   . GLY A 1 474 ? 90.785  88.483  138.877 1.00 169.08 ? 473 GLY A O   1 
ATOM   2450  N N   . LEU A 1 475 ? 91.344  86.586  137.824 1.00 82.62  ? 474 LEU A N   1 
ATOM   2451  C CA  . LEU A 1 475 ? 90.765  85.708  138.810 1.00 117.84 ? 474 LEU A CA  1 
ATOM   2452  C C   . LEU A 1 475 ? 91.427  85.985  140.162 1.00 124.18 ? 474 LEU A C   1 
ATOM   2453  O O   . LEU A 1 475 ? 92.599  86.372  140.222 1.00 173.27 ? 474 LEU A O   1 
ATOM   2454  C CB  . LEU A 1 475 ? 91.004  84.276  138.315 1.00 106.27 ? 474 LEU A CB  1 
ATOM   2455  C CG  . LEU A 1 475 ? 90.669  83.114  139.251 1.00 123.84 ? 474 LEU A CG  1 
ATOM   2456  C CD1 . LEU A 1 475 ? 89.244  83.099  139.819 1.00 168.57 ? 474 LEU A CD1 1 
ATOM   2457  C CD2 . LEU A 1 475 ? 90.865  81.846  138.468 1.00 110.53 ? 474 LEU A CD2 1 
ATOM   2458  N N   . ASP A 1 476 ? 90.668  85.773  141.250 1.00 127.61 ? 475 ASP A N   1 
ATOM   2459  C CA  . ASP A 1 476 ? 91.207  85.941  142.583 1.00 161.83 ? 475 ASP A CA  1 
ATOM   2460  C C   . ASP A 1 476 ? 90.586  84.919  143.518 1.00 133.03 ? 475 ASP A C   1 
ATOM   2461  O O   . ASP A 1 476 ? 89.367  84.851  143.583 1.00 196.19 ? 475 ASP A O   1 
ATOM   2462  C CB  . ASP A 1 476 ? 90.941  87.369  143.061 1.00 219.50 ? 475 ASP A CB  1 
ATOM   2463  C CG  . ASP A 1 476 ? 91.407  87.695  144.480 1.00 327.89 ? 475 ASP A CG  1 
ATOM   2464  O OD1 . ASP A 1 476 ? 91.995  86.811  145.169 1.00 314.01 ? 475 ASP A OD1 1 
ATOM   2465  O OD2 . ASP A 1 476 ? 91.172  88.848  144.899 1.00 406.00 ? 475 ASP A OD2 1 
ATOM   2466  N N   . ALA A 1 477 ? 91.424  84.200  144.270 1.00 125.09 ? 476 ALA A N   1 
ATOM   2467  C CA  . ALA A 1 477 ? 90.941  83.179  145.188 1.00 175.58 ? 476 ALA A CA  1 
ATOM   2468  C C   . ALA A 1 477 ? 90.050  83.754  146.302 1.00 209.79 ? 476 ALA A C   1 
ATOM   2469  O O   . ALA A 1 477 ? 89.117  83.060  146.717 1.00 286.07 ? 476 ALA A O   1 
ATOM   2470  C CB  . ALA A 1 477 ? 92.112  82.431  145.777 1.00 214.94 ? 476 ALA A CB  1 
ATOM   2471  N N   . ALA A 1 478 ? 90.323  84.994  146.752 1.00 202.76 ? 477 ALA A N   1 
ATOM   2472  C CA  . ALA A 1 478 ? 89.594  85.631  147.849 1.00 204.25 ? 477 ALA A CA  1 
ATOM   2473  C C   . ALA A 1 478 ? 88.184  86.095  147.466 1.00 173.81 ? 477 ALA A C   1 
ATOM   2474  O O   . ALA A 1 478 ? 87.304  86.151  148.332 1.00 293.31 ? 477 ALA A O   1 
ATOM   2475  C CB  . ALA A 1 478 ? 90.374  86.812  148.372 1.00 247.62 ? 477 ALA A CB  1 
ATOM   2476  N N   . ALA A 1 479 ? 87.947  86.416  146.184 1.00 179.02 ? 478 ALA A N   1 
ATOM   2477  C CA  . ALA A 1 479 ? 86.722  87.083  145.748 1.00 224.24 ? 478 ALA A CA  1 
ATOM   2478  C C   . ALA A 1 479 ? 85.473  86.182  145.825 1.00 259.41 ? 478 ALA A C   1 
ATOM   2479  O O   . ALA A 1 479 ? 84.379  86.720  146.008 1.00 276.14 ? 478 ALA A O   1 
ATOM   2480  C CB  . ALA A 1 479 ? 86.932  87.609  144.351 1.00 265.99 ? 478 ALA A CB  1 
ATOM   2481  N N   . LEU A 1 480 ? 85.646  84.850  145.695 1.00 203.00 ? 479 LEU A N   1 
ATOM   2482  C CA  . LEU A 1 480 ? 84.602  83.853  145.901 1.00 218.43 ? 479 LEU A CA  1 
ATOM   2483  C C   . LEU A 1 480 ? 84.982  82.977  147.093 1.00 223.49 ? 479 LEU A C   1 
ATOM   2484  O O   . LEU A 1 480 ? 85.626  81.959  146.888 1.00 227.55 ? 479 LEU A O   1 
ATOM   2485  C CB  . LEU A 1 480 ? 84.460  83.015  144.630 1.00 238.63 ? 479 LEU A CB  1 
ATOM   2486  C CG  . LEU A 1 480 ? 83.405  83.451  143.628 1.00 258.35 ? 479 LEU A CG  1 
ATOM   2487  C CD1 . LEU A 1 480 ? 83.491  84.921  143.288 1.00 258.59 ? 479 LEU A CD1 1 
ATOM   2488  C CD2 . LEU A 1 480 ? 83.576  82.587  142.404 1.00 272.79 ? 479 LEU A CD2 1 
ATOM   2489  N N   . PRO A 1 481 ? 84.615  83.358  148.341 1.00 256.73 ? 480 PRO A N   1 
ATOM   2490  C CA  . PRO A 1 481 ? 85.217  82.772  149.551 1.00 299.96 ? 480 PRO A CA  1 
ATOM   2491  C C   . PRO A 1 481 ? 85.131  81.255  149.729 1.00 297.41 ? 480 PRO A C   1 
ATOM   2492  O O   . PRO A 1 481 ? 84.172  80.629  149.274 1.00 255.79 ? 480 PRO A O   1 
ATOM   2493  C CB  . PRO A 1 481 ? 84.432  83.462  150.687 1.00 340.83 ? 480 PRO A CB  1 
ATOM   2494  C CG  . PRO A 1 481 ? 83.968  84.766  150.078 1.00 327.74 ? 480 PRO A CG  1 
ATOM   2495  C CD  . PRO A 1 481 ? 83.626  84.409  148.648 1.00 252.18 ? 480 PRO A CD  1 
ATOM   2496  N N   . GLY A 1 482 ? 86.161  80.700  150.395 1.00 297.85 ? 481 GLY A N   1 
ATOM   2497  C CA  . GLY A 1 482 ? 86.196  79.303  150.804 1.00 302.95 ? 481 GLY A CA  1 
ATOM   2498  C C   . GLY A 1 482 ? 87.117  78.421  149.959 1.00 260.22 ? 481 GLY A C   1 
ATOM   2499  O O   . GLY A 1 482 ? 87.715  77.492  150.497 1.00 273.30 ? 481 GLY A O   1 
ATOM   2500  N N   . GLN A 1 483 ? 87.210  78.704  148.650 1.00 265.31 ? 482 GLN A N   1 
ATOM   2501  C CA  . GLN A 1 483 ? 87.987  77.908  147.705 1.00 268.23 ? 482 GLN A CA  1 
ATOM   2502  C C   . GLN A 1 483 ? 89.483  78.051  148.001 1.00 255.00 ? 482 GLN A C   1 
ATOM   2503  O O   . GLN A 1 483 ? 89.918  79.098  148.491 1.00 254.64 ? 482 GLN A O   1 
ATOM   2504  C CB  . GLN A 1 483 ? 87.669  78.301  146.255 1.00 240.90 ? 482 GLN A CB  1 
ATOM   2505  C CG  . GLN A 1 483 ? 88.106  79.712  145.905 1.00 249.65 ? 482 GLN A CG  1 
ATOM   2506  C CD  . GLN A 1 483 ? 87.781  80.159  144.504 1.00 270.96 ? 482 GLN A CD  1 
ATOM   2507  O OE1 . GLN A 1 483 ? 87.598  79.355  143.599 1.00 268.74 ? 482 GLN A OE1 1 
ATOM   2508  N NE2 . GLN A 1 483 ? 87.736  81.467  144.324 1.00 240.30 ? 482 GLN A NE2 1 
ATOM   2509  N N   . PRO A 1 484 ? 90.312  77.013  147.716 1.00 266.11 ? 483 PRO A N   1 
ATOM   2510  C CA  . PRO A 1 484 ? 91.719  77.035  148.126 1.00 287.88 ? 483 PRO A CA  1 
ATOM   2511  C C   . PRO A 1 484 ? 92.584  77.941  147.241 1.00 270.66 ? 483 PRO A C   1 
ATOM   2512  O O   . PRO A 1 484 ? 92.405  78.014  146.024 1.00 218.26 ? 483 PRO A O   1 
ATOM   2513  C CB  . PRO A 1 484 ? 92.126  75.556  148.026 1.00 275.67 ? 483 PRO A CB  1 
ATOM   2514  C CG  . PRO A 1 484 ? 91.254  75.008  146.909 1.00 254.28 ? 483 PRO A CG  1 
ATOM   2515  C CD  . PRO A 1 484 ? 89.953  75.771  147.001 1.00 245.91 ? 483 PRO A CD  1 
ATOM   2516  N N   . MET A 1 485 ? 93.541  78.618  147.884 1.00 242.77 ? 484 MET A N   1 
ATOM   2517  C CA  . MET A 1 485 ? 94.466  79.505  147.201 1.00 262.99 ? 484 MET A CA  1 
ATOM   2518  C C   . MET A 1 485 ? 95.436  78.739  146.292 1.00 269.01 ? 484 MET A C   1 
ATOM   2519  O O   . MET A 1 485 ? 96.132  79.382  145.502 1.00 348.16 ? 484 MET A O   1 
ATOM   2520  C CB  . MET A 1 485 ? 95.264  80.317  148.227 1.00 349.99 ? 484 MET A CB  1 
ATOM   2521  C CG  . MET A 1 485 ? 94.395  81.257  149.044 1.00 414.55 ? 484 MET A CG  1 
ATOM   2522  S SD  . MET A 1 485 ? 95.281  82.673  149.737 1.00 525.63 ? 484 MET A SD  1 
ATOM   2523  C CE  . MET A 1 485 ? 96.756  81.883  150.380 1.00 551.67 ? 484 MET A CE  1 
ATOM   2524  N N   . GLU A 1 486 ? 95.496  77.396  146.406 1.00 217.97 ? 485 GLU A N   1 
ATOM   2525  C CA  . GLU A 1 486 ? 96.227  76.539  145.479 1.00 289.05 ? 485 GLU A CA  1 
ATOM   2526  C C   . GLU A 1 486 ? 95.592  76.486  144.078 1.00 252.93 ? 485 GLU A C   1 
ATOM   2527  O O   . GLU A 1 486 ? 96.324  76.387  143.086 1.00 272.01 ? 485 GLU A O   1 
ATOM   2528  C CB  . GLU A 1 486 ? 96.311  75.131  146.085 1.00 359.70 ? 485 GLU A CB  1 
ATOM   2529  C CG  . GLU A 1 486 ? 97.048  74.100  145.234 1.00 451.92 ? 485 GLU A CG  1 
ATOM   2530  C CD  . GLU A 1 486 ? 97.128  72.698  145.822 1.00 506.32 ? 485 GLU A CD  1 
ATOM   2531  O OE1 . GLU A 1 486 ? 96.616  72.484  146.942 1.00 529.53 ? 485 GLU A OE1 1 
ATOM   2532  O OE2 . GLU A 1 486 ? 97.704  71.815  145.152 1.00 528.57 ? 485 GLU A OE2 1 
ATOM   2533  N N   . ALA A 1 487 ? 94.251  76.530  143.988 1.00 153.88 ? 486 ALA A N   1 
ATOM   2534  C CA  . ALA A 1 487 ? 93.532  76.012  142.826 1.00 127.09 ? 486 ALA A CA  1 
ATOM   2535  C C   . ALA A 1 487 ? 92.102  76.554  142.772 1.00 115.56 ? 486 ALA A C   1 
ATOM   2536  O O   . ALA A 1 487 ? 91.100  75.845  142.956 1.00 117.27 ? 486 ALA A O   1 
ATOM   2537  C CB  . ALA A 1 487 ? 93.521  74.500  142.881 1.00 203.66 ? 486 ALA A CB  1 
ATOM   2538  N N   . PRO A 1 488 ? 91.943  77.862  142.524 1.00 100.96 ? 487 PRO A N   1 
ATOM   2539  C CA  . PRO A 1 488 ? 90.629  78.476  142.456 1.00 115.59 ? 487 PRO A CA  1 
ATOM   2540  C C   . PRO A 1 488 ? 89.912  78.132  141.170 1.00 101.01 ? 487 PRO A C   1 
ATOM   2541  O O   . PRO A 1 488 ? 90.550  77.992  140.141 1.00 74.41  ? 487 PRO A O   1 
ATOM   2542  C CB  . PRO A 1 488 ? 90.949  79.983  142.477 1.00 130.95 ? 487 PRO A CB  1 
ATOM   2543  C CG  . PRO A 1 488 ? 92.238  80.022  141.785 1.00 94.99  ? 487 PRO A CG  1 
ATOM   2544  C CD  . PRO A 1 488 ? 93.009  78.835  142.311 1.00 110.22 ? 487 PRO A CD  1 
ATOM   2545  N N   . VAL A 1 489 ? 88.576  78.033  141.284 1.00 132.61 ? 488 VAL A N   1 
ATOM   2546  C CA  . VAL A 1 489 ? 87.735  77.548  140.212 1.00 135.57 ? 488 VAL A CA  1 
ATOM   2547  C C   . VAL A 1 489 ? 87.627  78.626  139.158 1.00 104.05 ? 488 VAL A C   1 
ATOM   2548  O O   . VAL A 1 489 ? 87.304  79.761  139.501 1.00 93.50  ? 488 VAL A O   1 
ATOM   2549  C CB  . VAL A 1 489 ? 86.334  77.177  140.700 1.00 166.57 ? 488 VAL A CB  1 
ATOM   2550  C CG1 . VAL A 1 489 ? 85.447  76.742  139.527 1.00 196.67 ? 488 VAL A CG1 1 
ATOM   2551  C CG2 . VAL A 1 489 ? 86.418  76.121  141.803 1.00 204.98 ? 488 VAL A CG2 1 
ATOM   2552  N N   . MET A 1 490 ? 87.875  78.214  137.909 1.00 78.61  ? 489 MET A N   1 
ATOM   2553  C CA  . MET A 1 490 ? 87.954  79.159  136.822 1.00 92.51  ? 489 MET A CA  1 
ATOM   2554  C C   . MET A 1 490 ? 86.535  79.580  136.431 1.00 109.41 ? 489 MET A C   1 
ATOM   2555  O O   . MET A 1 490 ? 85.641  78.723  136.362 1.00 115.42 ? 489 MET A O   1 
ATOM   2556  C CB  . MET A 1 490 ? 88.669  78.487  135.663 1.00 81.61  ? 489 MET A CB  1 
ATOM   2557  C CG  . MET A 1 490 ? 88.724  79.280  134.402 1.00 101.61 ? 489 MET A CG  1 
ATOM   2558  S SD  . MET A 1 490 ? 89.566  80.806  134.515 1.00 93.68  ? 489 MET A SD  1 
ATOM   2559  C CE  . MET A 1 490 ? 89.788  81.182  132.771 1.00 83.41  ? 489 MET A CE  1 
ATOM   2560  N N   . LEU A 1 491 ? 86.356  80.899  136.193 1.00 73.45  ? 490 LEU A N   1 
ATOM   2561  C CA  . LEU A 1 491 ? 85.039  81.470  135.975 1.00 108.30 ? 490 LEU A CA  1 
ATOM   2562  C C   . LEU A 1 491 ? 84.773  81.698  134.486 1.00 124.92 ? 490 LEU A C   1 
ATOM   2563  O O   . LEU A 1 491 ? 84.986  82.789  133.944 1.00 80.52  ? 490 LEU A O   1 
ATOM   2564  C CB  . LEU A 1 491 ? 84.918  82.781  136.752 1.00 95.80  ? 490 LEU A CB  1 
ATOM   2565  C CG  . LEU A 1 491 ? 85.217  82.712  138.240 1.00 122.18 ? 490 LEU A CG  1 
ATOM   2566  C CD1 . LEU A 1 491 ? 84.842  84.030  138.904 1.00 204.20 ? 490 LEU A CD1 1 
ATOM   2567  C CD2 . LEU A 1 491 ? 84.477  81.581  138.913 1.00 132.06 ? 490 LEU A CD2 1 
ATOM   2568  N N   . TRP A 1 492 ? 84.247  80.655  133.839 1.00 107.82 ? 491 TRP A N   1 
ATOM   2569  C CA  . TRP A 1 492 ? 83.943  80.741  132.427 1.00 108.29 ? 491 TRP A CA  1 
ATOM   2570  C C   . TRP A 1 492 ? 82.719  81.585  132.140 1.00 140.08 ? 491 TRP A C   1 
ATOM   2571  O O   . TRP A 1 492 ? 82.759  82.427  131.248 1.00 162.02 ? 491 TRP A O   1 
ATOM   2572  C CB  . TRP A 1 492 ? 83.702  79.343  131.929 1.00 151.72 ? 491 TRP A CB  1 
ATOM   2573  C CG  . TRP A 1 492 ? 84.915  78.501  132.127 1.00 142.98 ? 491 TRP A CG  1 
ATOM   2574  C CD1 . TRP A 1 492 ? 85.177  77.574  133.090 1.00 135.52 ? 491 TRP A CD1 1 
ATOM   2575  C CD2 . TRP A 1 492 ? 86.056  78.550  131.265 1.00 124.36 ? 491 TRP A CD2 1 
ATOM   2576  N NE1 . TRP A 1 492 ? 86.408  77.025  132.868 1.00 139.58 ? 491 TRP A NE1 1 
ATOM   2577  C CE2 . TRP A 1 492 ? 86.969  77.608  131.769 1.00 119.59 ? 491 TRP A CE2 1 
ATOM   2578  C CE3 . TRP A 1 492 ? 86.375  79.296  130.132 1.00 121.93 ? 491 TRP A CE3 1 
ATOM   2579  C CZ2 . TRP A 1 492 ? 88.195  77.403  131.167 1.00 131.33 ? 491 TRP A CZ2 1 
ATOM   2580  C CZ3 . TRP A 1 492 ? 87.589  79.104  129.549 1.00 88.83  ? 491 TRP A CZ3 1 
ATOM   2581  C CH2 . TRP A 1 492 ? 88.472  78.176  130.068 1.00 120.99 ? 491 TRP A CH2 1 
ATOM   2582  N N   . ASP A 1 493 ? 81.651  81.333  132.907 1.00 169.81 ? 492 ASP A N   1 
ATOM   2583  C CA  . ASP A 1 493 ? 80.397  82.072  132.813 1.00 209.26 ? 492 ASP A CA  1 
ATOM   2584  C C   . ASP A 1 493 ? 79.728  82.062  134.194 1.00 193.52 ? 492 ASP A C   1 
ATOM   2585  O O   . ASP A 1 493 ? 80.233  81.412  135.108 1.00 156.37 ? 492 ASP A O   1 
ATOM   2586  C CB  . ASP A 1 493 ? 79.522  81.469  131.710 1.00 237.34 ? 492 ASP A CB  1 
ATOM   2587  C CG  . ASP A 1 493 ? 79.000  80.076  132.044 1.00 274.77 ? 492 ASP A CG  1 
ATOM   2588  O OD1 . ASP A 1 493 ? 78.274  79.956  133.056 1.00 296.11 ? 492 ASP A OD1 1 
ATOM   2589  O OD2 . ASP A 1 493 ? 79.321  79.118  131.295 1.00 243.29 ? 492 ASP A OD2 1 
ATOM   2590  N N   . GLU A 1 494 ? 78.579  82.746  134.358 1.00 185.89 ? 493 GLU A N   1 
ATOM   2591  C CA  . GLU A 1 494 ? 78.030  83.016  135.690 1.00 217.30 ? 493 GLU A CA  1 
ATOM   2592  C C   . GLU A 1 494 ? 77.631  81.743  136.457 1.00 198.22 ? 493 GLU A C   1 
ATOM   2593  O O   . GLU A 1 494 ? 77.459  81.812  137.685 1.00 203.71 ? 493 GLU A O   1 
ATOM   2594  C CB  . GLU A 1 494 ? 76.853  83.994  135.585 1.00 240.25 ? 493 GLU A CB  1 
ATOM   2595  C CG  . GLU A 1 494 ? 77.269  85.411  135.219 1.00 236.63 ? 493 GLU A CG  1 
ATOM   2596  C CD  . GLU A 1 494 ? 76.107  86.374  135.018 1.00 338.11 ? 493 GLU A CD  1 
ATOM   2597  O OE1 . GLU A 1 494 ? 75.400  86.664  136.007 1.00 358.81 ? 493 GLU A OE1 1 
ATOM   2598  O OE2 . GLU A 1 494 ? 75.894  86.834  133.864 1.00 438.61 ? 493 GLU A OE2 1 
ATOM   2599  N N   . SER A 1 495 ? 77.493  80.603  135.751 1.00 187.12 ? 494 SER A N   1 
ATOM   2600  C CA  . SER A 1 495 ? 77.221  79.311  136.366 1.00 218.31 ? 494 SER A CA  1 
ATOM   2601  C C   . SER A 1 495 ? 78.403  78.710  137.140 1.00 226.28 ? 494 SER A C   1 
ATOM   2602  O O   . SER A 1 495 ? 78.171  77.840  137.993 1.00 208.81 ? 494 SER A O   1 
ATOM   2603  C CB  . SER A 1 495 ? 76.784  78.339  135.306 1.00 247.59 ? 494 SER A CB  1 
ATOM   2604  O OG  . SER A 1 495 ? 77.903  77.915  134.528 1.00 272.04 ? 494 SER A OG  1 
ATOM   2605  N N   . SER A 1 496 ? 79.639  79.162  136.854 1.00 226.05 ? 495 SER A N   1 
ATOM   2606  C CA  . SER A 1 496 ? 80.850  78.383  137.062 1.00 210.83 ? 495 SER A CA  1 
ATOM   2607  C C   . SER A 1 496 ? 81.146  78.141  138.545 1.00 211.48 ? 495 SER A C   1 
ATOM   2608  O O   . SER A 1 496 ? 81.875  77.192  138.834 1.00 283.21 ? 495 SER A O   1 
ATOM   2609  C CB  . SER A 1 496 ? 82.050  79.038  136.379 1.00 166.79 ? 495 SER A CB  1 
ATOM   2610  O OG  . SER A 1 496 ? 81.793  79.318  135.001 1.00 126.38 ? 495 SER A OG  1 
ATOM   2611  N N   . PHE A 1 497 ? 80.615  78.970  139.471 1.00 164.57 ? 496 PHE A N   1 
ATOM   2612  C CA  . PHE A 1 497 ? 80.708  78.707  140.907 1.00 157.20 ? 496 PHE A CA  1 
ATOM   2613  C C   . PHE A 1 497 ? 79.322  78.622  141.508 1.00 220.52 ? 496 PHE A C   1 
ATOM   2614  O O   . PHE A 1 497 ? 78.836  79.595  142.093 1.00 278.78 ? 496 PHE A O   1 
ATOM   2615  C CB  . PHE A 1 497 ? 81.472  79.806  141.619 1.00 149.99 ? 496 PHE A CB  1 
ATOM   2616  C CG  . PHE A 1 497 ? 81.885  79.557  143.048 1.00 146.15 ? 496 PHE A CG  1 
ATOM   2617  C CD1 . PHE A 1 497 ? 82.840  78.595  143.398 1.00 213.32 ? 496 PHE A CD1 1 
ATOM   2618  C CD2 . PHE A 1 497 ? 81.351  80.336  144.050 1.00 196.97 ? 496 PHE A CD2 1 
ATOM   2619  C CE1 . PHE A 1 497 ? 83.229  78.409  144.719 1.00 220.05 ? 496 PHE A CE1 1 
ATOM   2620  C CE2 . PHE A 1 497 ? 81.744  80.151  145.374 1.00 278.34 ? 496 PHE A CE2 1 
ATOM   2621  C CZ  . PHE A 1 497 ? 82.674  79.184  145.709 1.00 246.71 ? 496 PHE A CZ  1 
ATOM   2622  N N   . PRO A 1 498 ? 78.659  77.449  141.378 1.00 265.36 ? 497 PRO A N   1 
ATOM   2623  C CA  . PRO A 1 498 ? 77.273  77.305  141.819 1.00 300.49 ? 497 PRO A CA  1 
ATOM   2624  C C   . PRO A 1 498 ? 77.104  77.137  143.332 1.00 284.29 ? 497 PRO A C   1 
ATOM   2625  O O   . PRO A 1 498 ? 75.973  77.219  143.807 1.00 368.06 ? 497 PRO A O   1 
ATOM   2626  C CB  . PRO A 1 498 ? 76.832  76.054  141.053 1.00 312.96 ? 497 PRO A CB  1 
ATOM   2627  C CG  . PRO A 1 498 ? 78.077  75.213  141.010 1.00 301.95 ? 497 PRO A CG  1 
ATOM   2628  C CD  . PRO A 1 498 ? 79.203  76.204  140.817 1.00 265.59 ? 497 PRO A CD  1 
ATOM   2629  N N   . ASP A 1 499 ? 78.211  76.932  144.072 1.00 237.55 ? 498 ASP A N   1 
ATOM   2630  C CA  . ASP A 1 499 ? 78.199  76.652  145.506 1.00 313.59 ? 498 ASP A CA  1 
ATOM   2631  C C   . ASP A 1 499 ? 77.686  77.832  146.356 1.00 332.08 ? 498 ASP A C   1 
ATOM   2632  O O   . ASP A 1 499 ? 77.223  77.613  147.477 1.00 344.69 ? 498 ASP A O   1 
ATOM   2633  C CB  . ASP A 1 499 ? 79.599  76.233  145.982 1.00 337.23 ? 498 ASP A CB  1 
ATOM   2634  C CG  . ASP A 1 499 ? 80.234  75.051  145.254 1.00 356.80 ? 498 ASP A CG  1 
ATOM   2635  O OD1 . ASP A 1 499 ? 79.566  74.446  144.391 1.00 307.52 ? 498 ASP A OD1 1 
ATOM   2636  O OD2 . ASP A 1 499 ? 81.407  74.737  145.561 1.00 369.33 ? 498 ASP A OD2 1 
ATOM   2637  N N   . ILE A 1 500 ? 77.784  79.072  145.845 1.00 284.61 ? 499 ILE A N   1 
ATOM   2638  C CA  . ILE A 1 500 ? 77.166  80.264  146.421 1.00 226.99 ? 499 ILE A CA  1 
ATOM   2639  C C   . ILE A 1 500 ? 76.630  81.067  145.235 1.00 259.04 ? 499 ILE A C   1 
ATOM   2640  O O   . ILE A 1 500 ? 77.286  82.014  144.763 1.00 280.23 ? 499 ILE A O   1 
ATOM   2641  C CB  . ILE A 1 500 ? 78.142  81.090  147.296 1.00 282.86 ? 499 ILE A CB  1 
ATOM   2642  C CG1 . ILE A 1 500 ? 78.846  80.242  148.368 1.00 338.77 ? 499 ILE A CG1 1 
ATOM   2643  C CG2 . ILE A 1 500 ? 77.423  82.290  147.913 1.00 307.01 ? 499 ILE A CG2 1 
ATOM   2644  C CD1 . ILE A 1 500 ? 79.988  80.943  149.098 1.00 337.84 ? 499 ILE A CD1 1 
ATOM   2645  N N   . PRO A 1 501 ? 75.433  80.711  144.704 1.00 293.43 ? 500 PRO A N   1 
ATOM   2646  C CA  . PRO A 1 501 ? 74.986  81.244  143.413 1.00 301.68 ? 500 PRO A CA  1 
ATOM   2647  C C   . PRO A 1 501 ? 74.614  82.725  143.542 1.00 292.75 ? 500 PRO A C   1 
ATOM   2648  O O   . PRO A 1 501 ? 74.078  83.150  144.569 1.00 301.94 ? 500 PRO A O   1 
ATOM   2649  C CB  . PRO A 1 501 ? 73.793  80.347  143.044 1.00 322.54 ? 500 PRO A CB  1 
ATOM   2650  C CG  . PRO A 1 501 ? 73.261  79.845  144.384 1.00 324.78 ? 500 PRO A CG  1 
ATOM   2651  C CD  . PRO A 1 501 ? 74.450  79.804  145.325 1.00 281.21 ? 500 PRO A CD  1 
ATOM   2652  N N   . GLY A 1 502 ? 74.919  83.504  142.495 1.00 276.53 ? 501 GLY A N   1 
ATOM   2653  C CA  . GLY A 1 502 ? 74.707  84.946  142.511 1.00 318.50 ? 501 GLY A CA  1 
ATOM   2654  C C   . GLY A 1 502 ? 75.910  85.766  142.990 1.00 340.19 ? 501 GLY A C   1 
ATOM   2655  O O   . GLY A 1 502 ? 75.869  86.990  142.852 1.00 285.92 ? 501 GLY A O   1 
ATOM   2656  N N   . ALA A 1 503 ? 76.964  85.114  143.533 1.00 346.89 ? 502 ALA A N   1 
ATOM   2657  C CA  . ALA A 1 503 ? 78.203  85.780  143.950 1.00 293.87 ? 502 ALA A CA  1 
ATOM   2658  C C   . ALA A 1 503 ? 79.059  86.245  142.751 1.00 248.99 ? 502 ALA A C   1 
ATOM   2659  O O   . ALA A 1 503 ? 79.700  87.298  142.800 1.00 176.67 ? 502 ALA A O   1 
ATOM   2660  C CB  . ALA A 1 503 ? 78.976  84.853  144.870 1.00 239.04 ? 502 ALA A CB  1 
ATOM   2661  N N   . VAL A 1 504 ? 79.058  85.451  141.668 1.00 234.47 ? 503 VAL A N   1 
ATOM   2662  C CA  . VAL A 1 504 ? 79.764  85.729  140.424 1.00 156.90 ? 503 VAL A CA  1 
ATOM   2663  C C   . VAL A 1 504 ? 79.035  86.825  139.657 1.00 147.25 ? 503 VAL A C   1 
ATOM   2664  O O   . VAL A 1 504 ? 77.894  86.641  139.237 1.00 190.63 ? 503 VAL A O   1 
ATOM   2665  C CB  . VAL A 1 504 ? 79.781  84.491  139.516 1.00 185.06 ? 503 VAL A CB  1 
ATOM   2666  C CG1 . VAL A 1 504 ? 80.470  84.817  138.196 1.00 193.16 ? 503 VAL A CG1 1 
ATOM   2667  C CG2 . VAL A 1 504 ? 80.374  83.283  140.206 1.00 176.06 ? 503 VAL A CG2 1 
ATOM   2668  N N   . SER A 1 505 ? 79.694  87.959  139.478 1.00 164.82 ? 504 SER A N   1 
ATOM   2669  C CA  . SER A 1 505 ? 79.253  89.014  138.580 1.00 160.37 ? 504 SER A CA  1 
ATOM   2670  C C   . SER A 1 505 ? 79.680  88.683  137.152 1.00 108.27 ? 504 SER A C   1 
ATOM   2671  O O   . SER A 1 505 ? 80.679  88.003  136.959 1.00 179.90 ? 504 SER A O   1 
ATOM   2672  C CB  . SER A 1 505 ? 79.849  90.318  139.104 1.00 196.04 ? 504 SER A CB  1 
ATOM   2673  O OG  . SER A 1 505 ? 79.583  91.447  138.272 1.00 256.52 ? 504 SER A OG  1 
ATOM   2674  N N   . ALA A 1 506 ? 78.992  89.227  136.150 1.00 150.80 ? 505 ALA A N   1 
ATOM   2675  C CA  . ALA A 1 506 ? 79.321  88.987  134.738 1.00 172.78 ? 505 ALA A CA  1 
ATOM   2676  C C   . ALA A 1 506 ? 80.763  89.345  134.408 1.00 184.77 ? 505 ALA A C   1 
ATOM   2677  O O   . ALA A 1 506 ? 81.454  88.477  133.894 1.00 182.46 ? 505 ALA A O   1 
ATOM   2678  C CB  . ALA A 1 506 ? 78.395  89.744  133.814 1.00 226.86 ? 505 ALA A CB  1 
ATOM   2679  N N   . ASN A 1 507 ? 81.189  90.580  134.725 1.00 195.10 ? 506 ASN A N   1 
ATOM   2680  C CA  . ASN A 1 507 ? 82.558  91.077  134.553 1.00 163.70 ? 506 ASN A CA  1 
ATOM   2681  C C   . ASN A 1 507 ? 83.664  90.222  135.197 1.00 123.26 ? 506 ASN A C   1 
ATOM   2682  O O   . ASN A 1 507 ? 84.805  90.331  134.733 1.00 250.06 ? 506 ASN A O   1 
ATOM   2683  C CB  . ASN A 1 507 ? 82.732  92.511  135.065 1.00 178.28 ? 506 ASN A CB  1 
ATOM   2684  C CG  . ASN A 1 507 ? 82.410  92.667  136.532 1.00 194.68 ? 506 ASN A CG  1 
ATOM   2685  O OD1 . ASN A 1 507 ? 82.061  91.678  137.181 1.00 155.55 ? 506 ASN A OD1 1 
ATOM   2686  N ND2 . ASN A 1 507 ? 82.513  93.885  137.049 1.00 242.88 ? 506 ASN A ND2 1 
ATOM   2687  N N   . MET A 1 508 ? 83.386  89.348  136.190 1.00 127.42 ? 507 MET A N   1 
ATOM   2688  C CA  . MET A 1 508 ? 84.356  88.372  136.717 1.00 135.36 ? 507 MET A CA  1 
ATOM   2689  C C   . MET A 1 508 ? 84.623  87.147  135.822 1.00 114.80 ? 507 MET A C   1 
ATOM   2690  O O   . MET A 1 508 ? 85.518  86.401  136.164 1.00 176.53 ? 507 MET A O   1 
ATOM   2691  C CB  . MET A 1 508 ? 83.916  87.841  138.083 1.00 130.20 ? 507 MET A CB  1 
ATOM   2692  C CG  . MET A 1 508 ? 83.719  88.949  139.112 1.00 181.94 ? 507 MET A CG  1 
ATOM   2693  S SD  . MET A 1 508 ? 83.138  88.387  140.728 1.00 210.63 ? 507 MET A SD  1 
ATOM   2694  C CE  . MET A 1 508 ? 84.624  87.514  141.208 1.00 181.87 ? 507 MET A CE  1 
ATOM   2695  N N   . THR A 1 509 ? 83.935  86.953  134.692 1.00 108.49 ? 508 THR A N   1 
ATOM   2696  C CA  . THR A 1 509 ? 83.930  85.697  133.965 1.00 106.22 ? 508 THR A CA  1 
ATOM   2697  C C   . THR A 1 509 ? 84.391  85.864  132.528 1.00 112.92 ? 508 THR A C   1 
ATOM   2698  O O   . THR A 1 509 ? 84.323  86.950  131.951 1.00 124.02 ? 508 THR A O   1 
ATOM   2699  C CB  . THR A 1 509 ? 82.532  85.113  133.848 1.00 145.39 ? 508 THR A CB  1 
ATOM   2700  O OG1 . THR A 1 509 ? 81.730  85.900  132.945 1.00 170.70 ? 508 THR A OG1 1 
ATOM   2701  C CG2 . THR A 1 509 ? 81.897  85.026  135.218 1.00 163.79 ? 508 THR A CG2 1 
ATOM   2702  N N   . VAL A 1 510 ? 84.851  84.755  131.944 1.00 96.58  ? 509 VAL A N   1 
ATOM   2703  C CA  . VAL A 1 510 ? 85.459  84.823  130.626 1.00 111.67 ? 509 VAL A CA  1 
ATOM   2704  C C   . VAL A 1 510 ? 84.443  85.330  129.606 1.00 141.75 ? 509 VAL A C   1 
ATOM   2705  O O   . VAL A 1 510 ? 84.767  86.175  128.766 1.00 102.08 ? 509 VAL A O   1 
ATOM   2706  C CB  . VAL A 1 510 ? 86.015  83.468  130.173 1.00 94.00  ? 509 VAL A CB  1 
ATOM   2707  C CG1 . VAL A 1 510 ? 86.540  83.609  128.753 1.00 104.69 ? 509 VAL A CG1 1 
ATOM   2708  C CG2 . VAL A 1 510 ? 87.098  82.903  131.070 1.00 108.37 ? 509 VAL A CG2 1 
ATOM   2709  N N   . LYS A 1 511 ? 83.229  84.778  129.693 1.00 185.08 ? 510 LYS A N   1 
ATOM   2710  C CA  . LYS A 1 511 ? 82.123  85.134  128.823 1.00 198.92 ? 510 LYS A CA  1 
ATOM   2711  C C   . LYS A 1 511 ? 81.837  86.624  128.960 1.00 168.78 ? 510 LYS A C   1 
ATOM   2712  O O   . LYS A 1 511 ? 81.571  87.289  127.952 1.00 169.06 ? 510 LYS A O   1 
ATOM   2713  C CB  . LYS A 1 511 ? 80.901  84.287  129.194 1.00 263.77 ? 510 LYS A CB  1 
ATOM   2714  C CG  . LYS A 1 511 ? 79.713  84.412  128.253 1.00 314.62 ? 510 LYS A CG  1 
ATOM   2715  C CD  . LYS A 1 511 ? 78.500  83.646  128.718 1.00 343.45 ? 510 LYS A CD  1 
ATOM   2716  C CE  . LYS A 1 511 ? 77.383  83.628  127.694 1.00 404.69 ? 510 LYS A CE  1 
ATOM   2717  N NZ  . LYS A 1 511 ? 77.749  82.885  126.461 1.00 462.04 ? 510 LYS A NZ  1 
ATOM   2718  N N   . GLY A 1 512 ? 81.887  87.130  130.206 1.00 137.19 ? 511 GLY A N   1 
ATOM   2719  C CA  . GLY A 1 512 ? 81.555  88.515  130.492 1.00 181.24 ? 511 GLY A CA  1 
ATOM   2720  C C   . GLY A 1 512 ? 82.625  89.536  130.115 1.00 164.29 ? 511 GLY A C   1 
ATOM   2721  O O   . GLY A 1 512 ? 82.334  90.730  130.003 1.00 156.75 ? 511 GLY A O   1 
ATOM   2722  N N   . GLN A 1 513 ? 83.862  89.064  129.958 1.00 178.68 ? 512 GLN A N   1 
ATOM   2723  C CA  . GLN A 1 513 ? 84.954  89.906  129.498 1.00 159.90 ? 512 GLN A CA  1 
ATOM   2724  C C   . GLN A 1 513 ? 85.073  89.818  127.990 1.00 131.08 ? 512 GLN A C   1 
ATOM   2725  O O   . GLN A 1 513 ? 85.445  90.814  127.383 1.00 175.45 ? 512 GLN A O   1 
ATOM   2726  C CB  . GLN A 1 513 ? 86.271  89.527  130.185 1.00 131.23 ? 512 GLN A CB  1 
ATOM   2727  C CG  . GLN A 1 513 ? 86.176  89.822  131.653 1.00 156.84 ? 512 GLN A CG  1 
ATOM   2728  C CD  . GLN A 1 513 ? 87.447  89.740  132.413 1.00 140.87 ? 512 GLN A CD  1 
ATOM   2729  O OE1 . GLN A 1 513 ? 88.545  89.849  131.883 1.00 234.67 ? 512 GLN A OE1 1 
ATOM   2730  N NE2 . GLN A 1 513 ? 87.269  89.590  133.703 1.00 158.11 ? 512 GLN A NE2 1 
ATOM   2731  N N   . SER A 1 514 ? 84.775  88.652  127.398 1.00 106.83 ? 513 SER A N   1 
ATOM   2732  C CA  . SER A 1 514 ? 85.136  88.399  126.016 1.00 141.98 ? 513 SER A CA  1 
ATOM   2733  C C   . SER A 1 514 ? 84.489  89.406  125.063 1.00 202.30 ? 513 SER A C   1 
ATOM   2734  O O   . SER A 1 514 ? 85.025  89.639  123.972 1.00 226.87 ? 513 SER A O   1 
ATOM   2735  C CB  . SER A 1 514 ? 84.777  86.980  125.648 1.00 190.59 ? 513 SER A CB  1 
ATOM   2736  O OG  . SER A 1 514 ? 85.588  86.028  126.337 1.00 146.12 ? 513 SER A OG  1 
ATOM   2737  N N   . GLU A 1 515 ? 83.345  89.966  125.502 1.00 196.98 ? 514 GLU A N   1 
ATOM   2738  C CA  . GLU A 1 515 ? 82.538  90.905  124.738 1.00 217.63 ? 514 GLU A CA  1 
ATOM   2739  C C   . GLU A 1 515 ? 83.061  92.346  124.785 1.00 216.89 ? 514 GLU A C   1 
ATOM   2740  O O   . GLU A 1 515 ? 82.755  93.115  123.870 1.00 294.09 ? 514 GLU A O   1 
ATOM   2741  C CB  . GLU A 1 515 ? 81.095  90.842  125.254 1.00 231.24 ? 514 GLU A CB  1 
ATOM   2742  C CG  . GLU A 1 515 ? 80.888  91.296  126.692 1.00 219.32 ? 514 GLU A CG  1 
ATOM   2743  C CD  . GLU A 1 515 ? 79.431  91.406  127.115 1.00 330.13 ? 514 GLU A CD  1 
ATOM   2744  O OE1 . GLU A 1 515 ? 78.679  90.431  126.902 1.00 381.72 ? 514 GLU A OE1 1 
ATOM   2745  O OE2 . GLU A 1 515 ? 79.048  92.465  127.661 1.00 396.96 ? 514 GLU A OE2 1 
ATOM   2746  N N   . ASP A 1 516 ? 83.836  92.712  125.822 1.00 167.12 ? 515 ASP A N   1 
ATOM   2747  C CA  . ASP A 1 516 ? 84.062  94.097  126.224 1.00 159.71 ? 515 ASP A CA  1 
ATOM   2748  C C   . ASP A 1 516 ? 85.505  94.511  125.893 1.00 170.55 ? 515 ASP A C   1 
ATOM   2749  O O   . ASP A 1 516 ? 86.437  93.986  126.520 1.00 293.57 ? 515 ASP A O   1 
ATOM   2750  C CB  . ASP A 1 516 ? 83.712  94.224  127.710 1.00 161.79 ? 515 ASP A CB  1 
ATOM   2751  C CG  . ASP A 1 516 ? 84.069  95.562  128.339 1.00 223.05 ? 515 ASP A CG  1 
ATOM   2752  O OD1 . ASP A 1 516 ? 84.599  96.449  127.594 1.00 149.52 ? 515 ASP A OD1 1 
ATOM   2753  O OD2 . ASP A 1 516 ? 83.816  95.709  129.575 1.00 247.14 ? 515 ASP A OD2 1 
ATOM   2754  N N   . PRO A 1 517 ? 85.749  95.435  124.924 1.00 178.44 ? 516 PRO A N   1 
ATOM   2755  C CA  . PRO A 1 517 ? 87.103  95.912  124.615 1.00 196.42 ? 516 PRO A CA  1 
ATOM   2756  C C   . PRO A 1 517 ? 87.887  96.525  125.776 1.00 197.95 ? 516 PRO A C   1 
ATOM   2757  O O   . PRO A 1 517 ? 89.120  96.506  125.743 1.00 251.72 ? 516 PRO A O   1 
ATOM   2758  C CB  . PRO A 1 517 ? 86.880  96.991  123.547 1.00 241.94 ? 516 PRO A CB  1 
ATOM   2759  C CG  . PRO A 1 517 ? 85.617  96.535  122.881 1.00 293.14 ? 516 PRO A CG  1 
ATOM   2760  C CD  . PRO A 1 517 ? 84.758  96.061  124.035 1.00 250.18 ? 516 PRO A CD  1 
ATOM   2761  N N   . GLY A 1 518 ? 87.175  97.057  126.778 1.00 162.39 ? 517 GLY A N   1 
ATOM   2762  C CA  . GLY A 1 518 ? 87.799  97.566  127.989 1.00 164.50 ? 517 GLY A CA  1 
ATOM   2763  C C   . GLY A 1 518 ? 88.261  96.505  128.986 1.00 116.02 ? 517 GLY A C   1 
ATOM   2764  O O   . GLY A 1 518 ? 89.026  96.859  129.859 1.00 194.37 ? 517 GLY A O   1 
ATOM   2765  N N   . SER A 1 519 ? 87.823  95.240  128.899 1.00 162.20 ? 518 SER A N   1 
ATOM   2766  C CA  . SER A 1 519 ? 88.092  94.218  129.924 1.00 152.84 ? 518 SER A CA  1 
ATOM   2767  C C   . SER A 1 519 ? 89.549  93.803  129.962 1.00 117.21 ? 518 SER A C   1 
ATOM   2768  O O   . SER A 1 519 ? 90.260  93.956  128.974 1.00 102.00 ? 518 SER A O   1 
ATOM   2769  C CB  . SER A 1 519 ? 87.314  92.954  129.672 1.00 173.31 ? 518 SER A CB  1 
ATOM   2770  O OG  . SER A 1 519 ? 87.758  92.349  128.455 1.00 145.57 ? 518 SER A OG  1 
ATOM   2771  N N   . LEU A 1 520 ? 89.943  93.234  131.105 1.00 122.27 ? 519 LEU A N   1 
ATOM   2772  C CA  . LEU A 1 520 ? 91.290  92.675  131.307 1.00 116.74 ? 519 LEU A CA  1 
ATOM   2773  C C   . LEU A 1 520 ? 91.692  91.651  130.232 1.00 84.81  ? 519 LEU A C   1 
ATOM   2774  O O   . LEU A 1 520 ? 92.725  91.754  129.620 1.00 74.49  ? 519 LEU A O   1 
ATOM   2775  C CB  . LEU A 1 520 ? 91.322  92.063  132.709 1.00 106.58 ? 519 LEU A CB  1 
ATOM   2776  C CG  . LEU A 1 520 ? 92.627  91.544  133.255 1.00 101.45 ? 519 LEU A CG  1 
ATOM   2777  C CD1 . LEU A 1 520 ? 93.807  92.447  132.947 1.00 163.91 ? 519 LEU A CD1 1 
ATOM   2778  C CD2 . LEU A 1 520 ? 92.490  91.462  134.750 1.00 139.78 ? 519 LEU A CD2 1 
ATOM   2779  N N   . LEU A 1 521 ? 90.834  90.682  129.959 1.00 113.59 ? 520 LEU A N   1 
ATOM   2780  C CA  . LEU A 1 521 ? 91.040  89.674  128.934 1.00 75.50  ? 520 LEU A CA  1 
ATOM   2781  C C   . LEU A 1 521 ? 91.097  90.292  127.555 1.00 73.33  ? 520 LEU A C   1 
ATOM   2782  O O   . LEU A 1 521 ? 91.796  89.744  126.732 1.00 87.34  ? 520 LEU A O   1 
ATOM   2783  C CB  . LEU A 1 521 ? 89.884  88.692  129.054 1.00 69.61  ? 520 LEU A CB  1 
ATOM   2784  C CG  . LEU A 1 521 ? 89.833  87.537  128.094 1.00 73.64  ? 520 LEU A CG  1 
ATOM   2785  C CD1 . LEU A 1 521 ? 90.960  86.657  128.336 1.00 110.36 ? 520 LEU A CD1 1 
ATOM   2786  C CD2 . LEU A 1 521 ? 88.606  86.688  128.326 1.00 105.17 ? 520 LEU A CD2 1 
ATOM   2787  N N   . SER A 1 522 ? 90.425  91.418  127.303 1.00 80.45  ? 521 SER A N   1 
ATOM   2788  C CA  . SER A 1 522 ? 90.614  92.085  126.026 1.00 121.76 ? 521 SER A CA  1 
ATOM   2789  C C   . SER A 1 522 ? 91.985  92.749  125.879 1.00 135.96 ? 521 SER A C   1 
ATOM   2790  O O   . SER A 1 522 ? 92.453  92.935  124.729 1.00 136.97 ? 521 SER A O   1 
ATOM   2791  C CB  . SER A 1 522 ? 89.506  93.039  125.802 1.00 161.59 ? 521 SER A CB  1 
ATOM   2792  O OG  . SER A 1 522 ? 88.311  92.312  125.570 1.00 233.12 ? 521 SER A OG  1 
ATOM   2793  N N   . LEU A 1 523 ? 92.589  93.100  127.032 1.00 100.32 ? 522 LEU A N   1 
ATOM   2794  C CA  . LEU A 1 523 ? 93.957  93.593  127.051 1.00 117.56 ? 522 LEU A CA  1 
ATOM   2795  C C   . LEU A 1 523 ? 94.931  92.415  126.894 1.00 105.24 ? 522 LEU A C   1 
ATOM   2796  O O   . LEU A 1 523 ? 95.918  92.537  126.176 1.00 109.43 ? 522 LEU A O   1 
ATOM   2797  C CB  . LEU A 1 523 ? 94.203  94.405  128.327 1.00 99.42  ? 522 LEU A CB  1 
ATOM   2798  C CG  . LEU A 1 523 ? 95.671  94.762  128.579 1.00 143.66 ? 522 LEU A CG  1 
ATOM   2799  C CD1 . LEU A 1 523 ? 96.092  95.825  127.513 1.00 122.05 ? 522 LEU A CD1 1 
ATOM   2800  C CD2 . LEU A 1 523 ? 95.975  95.112  130.077 1.00 135.01 ? 522 LEU A CD2 1 
ATOM   2801  N N   . PHE A 1 524 ? 94.682  91.285  127.557 1.00 76.50  ? 523 PHE A N   1 
ATOM   2802  C CA  . PHE A 1 524 ? 95.591  90.148  127.486 1.00 80.18  ? 523 PHE A CA  1 
ATOM   2803  C C   . PHE A 1 524 ? 95.660  89.647  126.072 1.00 88.52  ? 523 PHE A C   1 
ATOM   2804  O O   . PHE A 1 524 ? 96.740  89.430  125.557 1.00 92.53  ? 523 PHE A O   1 
ATOM   2805  C CB  . PHE A 1 524 ? 95.142  88.988  128.383 1.00 79.14  ? 523 PHE A CB  1 
ATOM   2806  C CG  . PHE A 1 524 ? 96.082  87.819  128.554 1.00 70.12  ? 523 PHE A CG  1 
ATOM   2807  C CD1 . PHE A 1 524 ? 96.339  86.965  127.523 1.00 56.94  ? 523 PHE A CD1 1 
ATOM   2808  C CD2 . PHE A 1 524 ? 96.731  87.595  129.769 1.00 98.07  ? 523 PHE A CD2 1 
ATOM   2809  C CE1 . PHE A 1 524 ? 97.202  85.905  127.735 1.00 86.85  ? 523 PHE A CE1 1 
ATOM   2810  C CE2 . PHE A 1 524 ? 97.606  86.533  129.966 1.00 99.58  ? 523 PHE A CE2 1 
ATOM   2811  C CZ  . PHE A 1 524 ? 97.821  85.663  128.946 1.00 79.31  ? 523 PHE A CZ  1 
ATOM   2812  N N   . ARG A 1 525 ? 94.482  89.475  125.483 1.00 114.40 ? 524 ARG A N   1 
ATOM   2813  C CA  . ARG A 1 525 ? 94.390  88.971  124.135 1.00 132.56 ? 524 ARG A CA  1 
ATOM   2814  C C   . ARG A 1 525 ? 95.180  89.884  123.220 1.00 104.02 ? 524 ARG A C   1 
ATOM   2815  O O   . ARG A 1 525 ? 95.908  89.379  122.366 1.00 119.68 ? 524 ARG A O   1 
ATOM   2816  C CB  . ARG A 1 525 ? 92.921  88.838  123.742 1.00 145.25 ? 524 ARG A CB  1 
ATOM   2817  C CG  . ARG A 1 525 ? 92.279  87.593  124.344 1.00 131.27 ? 524 ARG A CG  1 
ATOM   2818  C CD  . ARG A 1 525 ? 90.806  87.541  124.021 1.00 136.78 ? 524 ARG A CD  1 
ATOM   2819  N NE  . ARG A 1 525 ? 90.234  86.285  124.414 1.00 131.96 ? 524 ARG A NE  1 
ATOM   2820  C CZ  . ARG A 1 525 ? 88.935  86.085  124.423 1.00 185.24 ? 524 ARG A CZ  1 
ATOM   2821  N NH1 . ARG A 1 525 ? 88.434  84.939  124.871 1.00 203.52 ? 524 ARG A NH1 1 
ATOM   2822  N NH2 . ARG A 1 525 ? 88.155  87.072  123.997 1.00 191.91 ? 524 ARG A NH2 1 
ATOM   2823  N N   . ARG A 1 526 ? 95.025  91.189  123.424 1.00 77.15  ? 525 ARG A N   1 
ATOM   2824  C CA  . ARG A 1 526 ? 95.598  92.126  122.484 1.00 126.59 ? 525 ARG A CA  1 
ATOM   2825  C C   . ARG A 1 526 ? 97.138  92.151  122.573 1.00 99.08  ? 525 ARG A C   1 
ATOM   2826  O O   . ARG A 1 526 ? 97.829  92.233  121.558 1.00 86.84  ? 525 ARG A O   1 
ATOM   2827  C CB  . ARG A 1 526 ? 94.923  93.483  122.653 1.00 110.70 ? 525 ARG A CB  1 
ATOM   2828  C CG  . ARG A 1 526 ? 95.240  94.347  121.433 1.00 171.63 ? 525 ARG A CG  1 
ATOM   2829  C CD  . ARG A 1 526 ? 94.685  95.753  121.407 1.00 173.41 ? 525 ARG A CD  1 
ATOM   2830  N NE  . ARG A 1 526 ? 93.595  96.008  122.348 1.00 152.24 ? 525 ARG A NE  1 
ATOM   2831  C CZ  . ARG A 1 526 ? 93.310  97.221  122.796 1.00 210.76 ? 525 ARG A CZ  1 
ATOM   2832  N NH1 . ARG A 1 526 ? 92.513  97.383  123.844 1.00 218.92 ? 525 ARG A NH1 1 
ATOM   2833  N NH2 . ARG A 1 526 ? 93.863  98.266  122.190 1.00 215.87 ? 525 ARG A NH2 1 
ATOM   2834  N N   . LEU A 1 527 ? 97.643  92.079  123.789 1.00 94.98  ? 526 LEU A N   1 
ATOM   2835  C CA  . LEU A 1 527 ? 99.075  92.092  124.037 1.00 95.11  ? 526 LEU A CA  1 
ATOM   2836  C C   . LEU A 1 527 ? 99.724  90.818  123.587 1.00 74.31  ? 526 LEU A C   1 
ATOM   2837  O O   . LEU A 1 527 ? 100.858 90.866  123.107 1.00 59.41  ? 526 LEU A O   1 
ATOM   2838  C CB  . LEU A 1 527 ? 99.310  92.253  125.536 1.00 81.16  ? 526 LEU A CB  1 
ATOM   2839  C CG  . LEU A 1 527 ? 99.202  93.693  125.960 1.00 83.19  ? 526 LEU A CG  1 
ATOM   2840  C CD1 . LEU A 1 527 ? 99.126  93.675  127.450 1.00 93.90  ? 526 LEU A CD1 1 
ATOM   2841  C CD2 . LEU A 1 527 ? 100.381 94.516  125.368 1.00 93.63  ? 526 LEU A CD2 1 
ATOM   2842  N N   . SER A 1 528 ? 98.982  89.721  123.769 1.00 75.88  ? 527 SER A N   1 
ATOM   2843  C CA  . SER A 1 528 ? 99.531  88.428  123.467 1.00 99.10  ? 527 SER A CA  1 
ATOM   2844  C C   . SER A 1 528 ? 99.809  88.399  121.954 1.00 91.14  ? 527 SER A C   1 
ATOM   2845  O O   . SER A 1 528 ? 100.805 87.754  121.536 1.00 76.96  ? 527 SER A O   1 
ATOM   2846  C CB  . SER A 1 528 ? 98.633  87.330  124.056 1.00 79.56  ? 527 SER A CB  1 
ATOM   2847  O OG  . SER A 1 528 ? 99.242  86.034  123.898 1.00 108.91 ? 527 SER A OG  1 
ATOM   2848  N N   . ASP A 1 529 ? 98.939  89.106  121.184 1.00 75.01  ? 528 ASP A N   1 
ATOM   2849  C CA  . ASP A 1 529 ? 99.119  89.271  119.749 1.00 107.01 ? 528 ASP A CA  1 
ATOM   2850  C C   . ASP A 1 529 ? 100.478 89.913  119.465 1.00 97.67  ? 528 ASP A C   1 
ATOM   2851  O O   . ASP A 1 529 ? 101.300 89.372  118.715 1.00 105.53 ? 528 ASP A O   1 
ATOM   2852  C CB  . ASP A 1 529 ? 97.987  90.082  119.099 1.00 162.34 ? 528 ASP A CB  1 
ATOM   2853  C CG  . ASP A 1 529 ? 97.943  89.987  117.576 1.00 283.89 ? 528 ASP A CG  1 
ATOM   2854  O OD1 . ASP A 1 529 ? 98.114  88.860  117.041 1.00 340.25 ? 528 ASP A OD1 1 
ATOM   2855  O OD2 . ASP A 1 529 ? 97.732  91.041  116.929 1.00 351.08 ? 528 ASP A OD2 1 
ATOM   2856  N N   . GLN A 1 530 ? 100.693 91.078  120.061 1.00 77.63  ? 529 GLN A N   1 
ATOM   2857  C CA  . GLN A 1 530 ? 101.833 91.907  119.720 1.00 67.37  ? 529 GLN A CA  1 
ATOM   2858  C C   . GLN A 1 530 ? 103.113 91.174  120.052 1.00 81.50  ? 529 GLN A C   1 
ATOM   2859  O O   . GLN A 1 530 ? 103.992 91.171  119.224 1.00 102.42 ? 529 GLN A O   1 
ATOM   2860  C CB  . GLN A 1 530 ? 101.700 93.209  120.478 1.00 101.99 ? 529 GLN A CB  1 
ATOM   2861  C CG  . GLN A 1 530 ? 100.388 93.896  120.106 1.00 108.17 ? 529 GLN A CG  1 
ATOM   2862  C CD  . GLN A 1 530 ? 100.564 94.395  118.716 1.00 136.02 ? 529 GLN A CD  1 
ATOM   2863  O OE1 . GLN A 1 530 ? 101.702 94.499  118.250 1.00 93.87  ? 529 GLN A OE1 1 
ATOM   2864  N NE2 . GLN A 1 530 ? 99.448  94.720  118.082 1.00 203.30 ? 529 GLN A NE2 1 
ATOM   2865  N N   . ARG A 1 531 ? 103.187 90.543  121.234 1.00 88.91  ? 530 ARG A N   1 
ATOM   2866  C CA  . ARG A 1 531 ? 104.348 89.803  121.672 1.00 76.32  ? 530 ARG A CA  1 
ATOM   2867  C C   . ARG A 1 531 ? 104.648 88.636  120.776 1.00 95.43  ? 530 ARG A C   1 
ATOM   2868  O O   . ARG A 1 531 ? 105.785 88.149  120.855 1.00 151.78 ? 530 ARG A O   1 
ATOM   2869  C CB  . ARG A 1 531 ? 104.081 89.123  123.022 1.00 82.88  ? 530 ARG A CB  1 
ATOM   2870  C CG  . ARG A 1 531 ? 105.193 88.244  123.592 1.00 74.61  ? 530 ARG A CG  1 
ATOM   2871  C CD  . ARG A 1 531 ? 106.545 88.973  123.460 1.00 78.27  ? 530 ARG A CD  1 
ATOM   2872  N NE  . ARG A 1 531 ? 107.456 88.235  124.249 1.00 75.86  ? 530 ARG A NE  1 
ATOM   2873  C CZ  . ARG A 1 531 ? 107.987 87.124  123.840 1.00 77.70  ? 530 ARG A CZ  1 
ATOM   2874  N NH1 . ARG A 1 531 ? 108.714 86.337  124.618 1.00 114.46 ? 530 ARG A NH1 1 
ATOM   2875  N NH2 . ARG A 1 531 ? 107.755 86.768  122.612 1.00 81.42  ? 530 ARG A NH2 1 
ATOM   2876  N N   . SER A 1 532 ? 103.663 88.151  119.992 1.00 88.43  ? 531 SER A N   1 
ATOM   2877  C CA  . SER A 1 532 ? 103.904 86.924  119.256 1.00 124.64 ? 531 SER A CA  1 
ATOM   2878  C C   . SER A 1 532 ? 104.122 87.171  117.761 1.00 119.09 ? 531 SER A C   1 
ATOM   2879  O O   . SER A 1 532 ? 104.508 86.227  117.056 1.00 125.56 ? 531 SER A O   1 
ATOM   2880  C CB  . SER A 1 532 ? 102.806 85.958  119.600 1.00 137.82 ? 531 SER A CB  1 
ATOM   2881  O OG  . SER A 1 532 ? 101.563 86.436  119.149 1.00 168.53 ? 531 SER A OG  1 
ATOM   2882  N N   . LYS A 1 533 ? 103.896 88.419  117.311 1.00 89.41  ? 532 LYS A N   1 
ATOM   2883  C CA  . LYS A 1 533 ? 104.028 88.748  115.917 1.00 121.86 ? 532 LYS A CA  1 
ATOM   2884  C C   . LYS A 1 533 ? 105.226 89.666  115.680 1.00 88.57  ? 532 LYS A C   1 
ATOM   2885  O O   . LYS A 1 533 ? 105.834 89.562  114.618 1.00 132.61 ? 532 LYS A O   1 
ATOM   2886  C CB  . LYS A 1 533 ? 102.662 89.275  115.436 1.00 124.16 ? 532 LYS A CB  1 
ATOM   2887  C CG  . LYS A 1 533 ? 102.419 90.746  115.619 1.00 145.55 ? 532 LYS A CG  1 
ATOM   2888  C CD  . LYS A 1 533 ? 100.966 91.111  115.724 1.00 191.20 ? 532 LYS A CD  1 
ATOM   2889  C CE  . LYS A 1 533 ? 100.252 91.270  114.415 1.00 238.28 ? 532 LYS A CE  1 
ATOM   2890  N NZ  . LYS A 1 533 ? 98.965  91.975  114.619 1.00 282.55 ? 532 LYS A NZ  1 
ATOM   2891  N N   . GLU A 1 534 ? 105.511 90.583  116.601 1.00 90.27  ? 533 GLU A N   1 
ATOM   2892  C CA  . GLU A 1 534 ? 106.294 91.778  116.286 1.00 114.88 ? 533 GLU A CA  1 
ATOM   2893  C C   . GLU A 1 534 ? 107.765 91.521  116.553 1.00 92.56  ? 533 GLU A C   1 
ATOM   2894  O O   . GLU A 1 534 ? 108.131 91.111  117.649 1.00 146.62 ? 533 GLU A O   1 
ATOM   2895  C CB  . GLU A 1 534 ? 105.808 92.974  117.103 1.00 100.19 ? 533 GLU A CB  1 
ATOM   2896  C CG  . GLU A 1 534 ? 104.663 93.668  116.455 1.00 139.00 ? 533 GLU A CG  1 
ATOM   2897  C CD  . GLU A 1 534 ? 105.025 94.510  115.236 1.00 246.06 ? 533 GLU A CD  1 
ATOM   2898  O OE1 . GLU A 1 534 ? 106.236 94.542  114.818 1.00 207.85 ? 533 GLU A OE1 1 
ATOM   2899  O OE2 . GLU A 1 534 ? 104.090 95.154  114.698 1.00 330.23 ? 533 GLU A OE2 1 
ATOM   2900  N N   . ARG A 1 535 ? 108.612 91.754  115.561 1.00 109.83 ? 534 ARG A N   1 
ATOM   2901  C CA  . ARG A 1 535 ? 109.942 91.176  115.693 1.00 161.34 ? 534 ARG A CA  1 
ATOM   2902  C C   . ARG A 1 535 ? 110.695 91.911  116.794 1.00 92.70  ? 534 ARG A C   1 
ATOM   2903  O O   . ARG A 1 535 ? 111.594 91.359  117.413 1.00 83.36  ? 534 ARG A O   1 
ATOM   2904  C CB  . ARG A 1 535 ? 110.687 91.179  114.369 1.00 182.19 ? 534 ARG A CB  1 
ATOM   2905  C CG  . ARG A 1 535 ? 111.876 90.240  114.374 1.00 160.67 ? 534 ARG A CG  1 
ATOM   2906  C CD  . ARG A 1 535 ? 112.482 90.041  113.006 1.00 206.27 ? 534 ARG A CD  1 
ATOM   2907  N NE  . ARG A 1 535 ? 111.542 89.366  112.123 1.00 179.31 ? 534 ARG A NE  1 
ATOM   2908  C CZ  . ARG A 1 535 ? 111.121 89.846  110.953 1.00 197.94 ? 534 ARG A CZ  1 
ATOM   2909  N NH1 . ARG A 1 535 ? 110.382 89.075  110.173 1.00 303.67 ? 534 ARG A NH1 1 
ATOM   2910  N NH2 . ARG A 1 535 ? 111.443 91.071  110.548 1.00 135.69 ? 534 ARG A NH2 1 
ATOM   2911  N N   . SER A 1 536 ? 110.239 93.127  117.049 1.00 78.06  ? 535 SER A N   1 
ATOM   2912  C CA  . SER A 1 536 ? 110.824 93.936  118.108 1.00 114.38 ? 535 SER A CA  1 
ATOM   2913  C C   . SER A 1 536 ? 110.599 93.377  119.529 1.00 89.34  ? 535 SER A C   1 
ATOM   2914  O O   . SER A 1 536 ? 111.537 93.272  120.276 1.00 55.55  ? 535 SER A O   1 
ATOM   2915  C CB  . SER A 1 536 ? 110.284 95.309  117.954 1.00 95.86  ? 535 SER A CB  1 
ATOM   2916  O OG  . SER A 1 536 ? 111.290 96.225  118.307 1.00 78.47  ? 535 SER A OG  1 
ATOM   2917  N N   . LEU A 1 537 ? 109.373 92.998  119.896 1.00 84.57  ? 536 LEU A N   1 
ATOM   2918  C CA  . LEU A 1 537 ? 109.018 92.351  121.175 1.00 72.98  ? 536 LEU A CA  1 
ATOM   2919  C C   . LEU A 1 537 ? 109.449 90.891  121.170 1.00 75.62  ? 536 LEU A C   1 
ATOM   2920  O O   . LEU A 1 537 ? 109.825 90.383  122.233 1.00 100.35 ? 536 LEU A O   1 
ATOM   2921  C CB  . LEU A 1 537 ? 107.510 92.427  121.506 1.00 59.53  ? 536 LEU A CB  1 
ATOM   2922  C CG  . LEU A 1 537 ? 106.941 93.858  121.341 1.00 85.72  ? 536 LEU A CG  1 
ATOM   2923  C CD1 . LEU A 1 537 ? 105.470 93.951  121.734 1.00 82.65  ? 536 LEU A CD1 1 
ATOM   2924  C CD2 . LEU A 1 537 ? 107.778 94.917  122.107 1.00 94.10  ? 536 LEU A CD2 1 
ATOM   2925  N N   . LEU A 1 538 ? 109.444 90.255  120.002 1.00 75.73  ? 537 LEU A N   1 
ATOM   2926  C CA  . LEU A 1 538 ? 109.833 88.858  119.920 1.00 103.02 ? 537 LEU A CA  1 
ATOM   2927  C C   . LEU A 1 538 ? 111.280 88.631  120.261 1.00 82.27  ? 537 LEU A C   1 
ATOM   2928  O O   . LEU A 1 538 ? 111.491 87.628  120.940 1.00 174.64 ? 537 LEU A O   1 
ATOM   2929  C CB  . LEU A 1 538 ? 109.618 88.307  118.530 1.00 123.66 ? 537 LEU A CB  1 
ATOM   2930  C CG  . LEU A 1 538 ? 108.206 87.786  118.299 1.00 127.30 ? 537 LEU A CG  1 
ATOM   2931  C CD1 . LEU A 1 538 ? 107.906 87.785  116.826 1.00 133.25 ? 537 LEU A CD1 1 
ATOM   2932  C CD2 . LEU A 1 538 ? 108.097 86.380  118.879 1.00 124.43 ? 537 LEU A CD2 1 
ATOM   2933  N N   . HIS A 1 539 ? 112.197 89.512  119.828 1.00 60.47  ? 538 HIS A N   1 
ATOM   2934  C CA  . HIS A 1 539 ? 113.578 89.361  120.279 1.00 116.05 ? 538 HIS A CA  1 
ATOM   2935  C C   . HIS A 1 539 ? 114.488 90.577  120.160 1.00 104.98 ? 538 HIS A C   1 
ATOM   2936  O O   . HIS A 1 539 ? 115.750 90.427  120.182 1.00 102.41 ? 538 HIS A O   1 
ATOM   2937  C CB  . HIS A 1 539 ? 114.265 88.162  119.604 1.00 176.01 ? 538 HIS A CB  1 
ATOM   2938  C CG  . HIS A 1 539 ? 114.096 88.198  118.168 1.00 132.59 ? 538 HIS A CG  1 
ATOM   2939  N ND1 . HIS A 1 539 ? 114.542 89.249  117.432 1.00 84.95  ? 538 HIS A ND1 1 
ATOM   2940  C CD2 . HIS A 1 539 ? 113.533 87.332  117.367 1.00 154.73 ? 538 HIS A CD2 1 
ATOM   2941  C CE1 . HIS A 1 539 ? 114.222 88.973  116.208 1.00 117.04 ? 538 HIS A CE1 1 
ATOM   2942  N NE2 . HIS A 1 539 ? 113.605 87.825  116.149 1.00 120.58 ? 538 HIS A NE2 1 
ATOM   2943  N N   . GLY A 1 540 ? 113.830 91.741  120.111 1.00 68.33  ? 539 GLY A N   1 
ATOM   2944  C CA  . GLY A 1 540 ? 114.524 92.993  120.300 1.00 93.87  ? 539 GLY A CA  1 
ATOM   2945  C C   . GLY A 1 540 ? 115.460 93.095  121.521 1.00 97.24  ? 539 GLY A C   1 
ATOM   2946  O O   . GLY A 1 540 ? 115.432 92.309  122.471 1.00 117.53 ? 539 GLY A O   1 
ATOM   2947  N N   . ASP A 1 541 ? 116.304 94.140  121.451 1.00 95.74  ? 540 ASP A N   1 
ATOM   2948  C CA  . ASP A 1 541 ? 117.130 94.599  122.537 1.00 127.37 ? 540 ASP A CA  1 
ATOM   2949  C C   . ASP A 1 541 ? 116.203 95.307  123.512 1.00 126.05 ? 540 ASP A C   1 
ATOM   2950  O O   . ASP A 1 541 ? 114.990 95.385  123.222 1.00 106.61 ? 540 ASP A O   1 
ATOM   2951  C CB  . ASP A 1 541 ? 118.239 95.470  121.982 1.00 139.02 ? 540 ASP A CB  1 
ATOM   2952  C CG  . ASP A 1 541 ? 119.194 94.807  120.990 1.00 206.71 ? 540 ASP A CG  1 
ATOM   2953  O OD1 . ASP A 1 541 ? 119.373 93.566  121.035 1.00 296.04 ? 540 ASP A OD1 1 
ATOM   2954  O OD2 . ASP A 1 541 ? 119.767 95.552  120.167 1.00 330.91 ? 540 ASP A OD2 1 
ATOM   2955  N N   . PHE A 1 542 ? 116.763 95.742  124.668 1.00 92.41  ? 541 PHE A N   1 
ATOM   2956  C CA  . PHE A 1 542 ? 115.956 96.396  125.696 1.00 86.29  ? 541 PHE A CA  1 
ATOM   2957  C C   . PHE A 1 542 ? 116.765 97.529  126.313 1.00 94.67  ? 541 PHE A C   1 
ATOM   2958  O O   . PHE A 1 542 ? 117.880 97.261  126.742 1.00 126.50 ? 541 PHE A O   1 
ATOM   2959  C CB  . PHE A 1 542 ? 115.449 95.354  126.710 1.00 79.80  ? 541 PHE A CB  1 
ATOM   2960  C CG  . PHE A 1 542 ? 114.967 95.869  128.038 1.00 71.07  ? 541 PHE A CG  1 
ATOM   2961  C CD1 . PHE A 1 542 ? 115.897 96.104  129.036 1.00 74.01  ? 541 PHE A CD1 1 
ATOM   2962  C CD2 . PHE A 1 542 ? 113.633 96.119  128.305 1.00 61.44  ? 541 PHE A CD2 1 
ATOM   2963  C CE1 . PHE A 1 542 ? 115.492 96.580  130.268 1.00 70.24  ? 541 PHE A CE1 1 
ATOM   2964  C CE2 . PHE A 1 542 ? 113.243 96.595  129.551 1.00 68.40  ? 541 PHE A CE2 1 
ATOM   2965  C CZ  . PHE A 1 542 ? 114.160 96.833  130.528 1.00 61.80  ? 541 PHE A CZ  1 
ATOM   2966  N N   . HIS A 1 543 ? 116.200 98.757  126.367 1.00 66.90  ? 542 HIS A N   1 
ATOM   2967  C CA  . HIS A 1 543 ? 116.927 99.869  126.983 1.00 93.91  ? 542 HIS A CA  1 
ATOM   2968  C C   . HIS A 1 543 ? 115.949 100.515 127.901 1.00 100.71 ? 542 HIS A C   1 
ATOM   2969  O O   . HIS A 1 543 ? 115.037 101.124 127.393 1.00 132.13 ? 542 HIS A O   1 
ATOM   2970  C CB  . HIS A 1 543 ? 117.530 100.986 126.092 1.00 108.29 ? 542 HIS A CB  1 
ATOM   2971  C CG  . HIS A 1 543 ? 118.664 100.382 125.340 1.00 229.07 ? 542 HIS A CG  1 
ATOM   2972  N ND1 . HIS A 1 543 ? 118.673 99.905  124.028 1.00 393.52 ? 542 HIS A ND1 1 
ATOM   2973  C CD2 . HIS A 1 543 ? 119.882 100.172 125.834 1.00 240.82 ? 542 HIS A CD2 1 
ATOM   2974  C CE1 . HIS A 1 543 ? 119.883 99.433  123.747 1.00 412.77 ? 542 HIS A CE1 1 
ATOM   2975  N NE2 . HIS A 1 543 ? 120.634 99.586  124.833 1.00 339.21 ? 542 HIS A NE2 1 
ATOM   2976  N N   . ALA A 1 544 ? 116.174 100.367 129.212 1.00 92.95  ? 543 ALA A N   1 
ATOM   2977  C CA  . ALA A 1 544 ? 115.521 101.208 130.189 1.00 74.69  ? 543 ALA A CA  1 
ATOM   2978  C C   . ALA A 1 544 ? 116.050 102.639 130.164 1.00 86.83  ? 543 ALA A C   1 
ATOM   2979  O O   . ALA A 1 544 ? 117.229 102.854 129.866 1.00 180.75 ? 543 ALA A O   1 
ATOM   2980  C CB  . ALA A 1 544 ? 115.822 100.615 131.486 1.00 108.08 ? 543 ALA A CB  1 
ATOM   2981  N N   . PHE A 1 545 ? 115.201 103.611 130.481 1.00 71.36  ? 544 PHE A N   1 
ATOM   2982  C CA  . PHE A 1 545 ? 115.692 104.969 130.602 1.00 80.69  ? 544 PHE A CA  1 
ATOM   2983  C C   . PHE A 1 545 ? 114.830 105.800 131.551 1.00 99.14  ? 544 PHE A C   1 
ATOM   2984  O O   . PHE A 1 545 ? 113.695 105.396 131.866 1.00 88.81  ? 544 PHE A O   1 
ATOM   2985  C CB  . PHE A 1 545 ? 115.754 105.558 129.202 1.00 68.96  ? 544 PHE A CB  1 
ATOM   2986  C CG  . PHE A 1 545 ? 114.436 105.913 128.581 1.00 54.92  ? 544 PHE A CG  1 
ATOM   2987  C CD1 . PHE A 1 545 ? 113.775 105.016 127.806 1.00 46.35  ? 544 PHE A CD1 1 
ATOM   2988  C CD2 . PHE A 1 545 ? 113.864 107.164 128.753 1.00 84.95  ? 544 PHE A CD2 1 
ATOM   2989  C CE1 . PHE A 1 545 ? 112.571 105.317 127.219 1.00 57.27  ? 544 PHE A CE1 1 
ATOM   2990  C CE2 . PHE A 1 545 ? 112.654 107.474 128.148 1.00 87.13  ? 544 PHE A CE2 1 
ATOM   2991  C CZ  . PHE A 1 545 ? 112.014 106.543 127.379 1.00 83.32  ? 544 PHE A CZ  1 
ATOM   2992  N N   . SER A 1 546 ? 115.377 106.957 132.005 1.00 93.37  ? 545 SER A N   1 
ATOM   2993  C CA  . SER A 1 546 ? 114.645 107.716 133.018 1.00 105.54 ? 545 SER A CA  1 
ATOM   2994  C C   . SER A 1 546 ? 113.768 108.675 132.243 1.00 78.06  ? 545 SER A C   1 
ATOM   2995  O O   . SER A 1 546 ? 114.282 109.631 131.629 1.00 87.15  ? 545 SER A O   1 
ATOM   2996  C CB  . SER A 1 546 ? 115.492 108.390 134.105 1.00 133.83 ? 545 SER A CB  1 
ATOM   2997  O OG  . SER A 1 546 ? 116.525 107.539 134.591 1.00 133.77 ? 545 SER A OG  1 
ATOM   2998  N N   . ALA A 1 547 ? 112.465 108.371 132.249 1.00 63.40  ? 546 ALA A N   1 
ATOM   2999  C CA  . ALA A 1 547 ? 111.544 109.129 131.405 1.00 80.89  ? 546 ALA A CA  1 
ATOM   3000  C C   . ALA A 1 547 ? 110.775 110.149 132.214 1.00 69.37  ? 546 ALA A C   1 
ATOM   3001  O O   . ALA A 1 547 ? 110.105 110.957 131.612 1.00 58.66  ? 546 ALA A O   1 
ATOM   3002  C CB  . ALA A 1 547 ? 110.520 108.232 130.738 1.00 91.95  ? 546 ALA A CB  1 
ATOM   3003  N N   . GLY A 1 548 ? 110.827 110.089 133.552 1.00 78.35  ? 547 GLY A N   1 
ATOM   3004  C CA  . GLY A 1 548 ? 109.776 110.675 134.390 1.00 54.14  ? 547 GLY A CA  1 
ATOM   3005  C C   . GLY A 1 548 ? 109.861 110.154 135.816 1.00 54.73  ? 547 GLY A C   1 
ATOM   3006  O O   . GLY A 1 548 ? 110.572 109.150 135.969 1.00 73.63  ? 547 GLY A O   1 
ATOM   3007  N N   . PRO A 1 549 ? 109.264 110.812 136.874 1.00 51.01  ? 548 PRO A N   1 
ATOM   3008  C CA  . PRO A 1 549 ? 109.375 110.393 138.287 1.00 45.37  ? 548 PRO A CA  1 
ATOM   3009  C C   . PRO A 1 549 ? 108.846 109.016 138.598 1.00 62.38  ? 548 PRO A C   1 
ATOM   3010  O O   . PRO A 1 549 ? 109.687 108.223 139.017 1.00 77.40  ? 548 PRO A O   1 
ATOM   3011  C CB  . PRO A 1 549 ? 108.827 111.550 139.029 1.00 35.20  ? 548 PRO A CB  1 
ATOM   3012  C CG  . PRO A 1 549 ? 109.210 112.654 138.056 1.00 35.17  ? 548 PRO A CG  1 
ATOM   3013  C CD  . PRO A 1 549 ? 108.575 112.091 136.836 1.00 44.55  ? 548 PRO A CD  1 
ATOM   3014  N N   . GLY A 1 550 ? 107.609 108.628 138.353 1.00 62.97  ? 549 GLY A N   1 
ATOM   3015  C CA  . GLY A 1 550 ? 107.385 107.195 138.658 1.00 104.80 ? 549 GLY A CA  1 
ATOM   3016  C C   . GLY A 1 550 ? 107.834 106.137 137.627 1.00 63.36  ? 549 GLY A C   1 
ATOM   3017  O O   . GLY A 1 550 ? 108.128 104.981 137.920 1.00 65.12  ? 549 GLY A O   1 
ATOM   3018  N N   . LEU A 1 551 ? 107.886 106.599 136.393 1.00 69.58  ? 550 LEU A N   1 
ATOM   3019  C CA  . LEU A 1 551 ? 107.821 105.772 135.209 1.00 62.39  ? 550 LEU A CA  1 
ATOM   3020  C C   . LEU A 1 551 ? 108.988 104.811 135.133 1.00 78.17  ? 550 LEU A C   1 
ATOM   3021  O O   . LEU A 1 551 ? 110.151 105.264 135.247 1.00 79.10  ? 550 LEU A O   1 
ATOM   3022  C CB  . LEU A 1 551 ? 107.941 106.684 134.012 1.00 65.83  ? 550 LEU A CB  1 
ATOM   3023  C CG  . LEU A 1 551 ? 107.031 107.906 133.993 1.00 73.90  ? 550 LEU A CG  1 
ATOM   3024  C CD1 . LEU A 1 551 ? 107.265 108.728 132.683 1.00 103.29 ? 550 LEU A CD1 1 
ATOM   3025  C CD2 . LEU A 1 551 ? 105.591 107.425 134.171 1.00 58.51  ? 550 LEU A CD2 1 
ATOM   3026  N N   . PHE A 1 552 ? 108.623 103.516 134.984 1.00 57.30  ? 551 PHE A N   1 
ATOM   3027  C CA  . PHE A 1 552 ? 109.524 102.505 134.432 1.00 59.76  ? 551 PHE A CA  1 
ATOM   3028  C C   . PHE A 1 552 ? 109.375 102.547 132.953 1.00 59.84  ? 551 PHE A C   1 
ATOM   3029  O O   . PHE A 1 552 ? 108.278 102.237 132.521 1.00 45.71  ? 551 PHE A O   1 
ATOM   3030  C CB  . PHE A 1 552 ? 109.175 101.068 134.780 1.00 44.69  ? 551 PHE A CB  1 
ATOM   3031  C CG  . PHE A 1 552 ? 110.071 99.938  134.353 1.00 35.57  ? 551 PHE A CG  1 
ATOM   3032  C CD1 . PHE A 1 552 ? 111.327 100.079 133.845 1.00 47.23  ? 551 PHE A CD1 1 
ATOM   3033  C CD2 . PHE A 1 552 ? 109.615 98.660  134.506 1.00 44.91  ? 551 PHE A CD2 1 
ATOM   3034  C CE1 . PHE A 1 552 ? 112.101 98.985  133.471 1.00 57.42  ? 551 PHE A CE1 1 
ATOM   3035  C CE2 . PHE A 1 552 ? 110.377 97.576  134.136 1.00 53.42  ? 551 PHE A CE2 1 
ATOM   3036  C CZ  . PHE A 1 552 ? 111.634 97.735  133.628 1.00 57.63  ? 551 PHE A CZ  1 
ATOM   3037  N N   . SER A 1 553 ? 110.437 102.958 132.257 1.00 59.53  ? 552 SER A N   1 
ATOM   3038  C CA  . SER A 1 553 ? 110.208 103.195 130.867 1.00 67.43  ? 552 SER A CA  1 
ATOM   3039  C C   . SER A 1 553 ? 111.318 102.590 130.065 1.00 72.95  ? 552 SER A C   1 
ATOM   3040  O O   . SER A 1 553 ? 112.455 102.680 130.500 1.00 121.73 ? 552 SER A O   1 
ATOM   3041  C CB  . SER A 1 553 ? 110.051 104.609 130.611 1.00 61.53  ? 552 SER A CB  1 
ATOM   3042  O OG  . SER A 1 553 ? 109.706 104.688 129.246 1.00 77.91  ? 552 SER A OG  1 
ATOM   3043  N N   . TYR A 1 554 ? 110.972 101.991 128.928 1.00 56.36  ? 553 TYR A N   1 
ATOM   3044  C CA  . TYR A 1 554 ? 112.001 101.319 128.179 1.00 58.06  ? 553 TYR A CA  1 
ATOM   3045  C C   . TYR A 1 554 ? 111.571 101.127 126.751 1.00 68.43  ? 553 TYR A C   1 
ATOM   3046  O O   . TYR A 1 554 ? 110.396 101.058 126.498 1.00 56.06  ? 553 TYR A O   1 
ATOM   3047  C CB  . TYR A 1 554 ? 112.369 99.916  128.685 1.00 72.27  ? 553 TYR A CB  1 
ATOM   3048  C CG  . TYR A 1 554 ? 111.192 99.056  128.988 1.00 67.82  ? 553 TYR A CG  1 
ATOM   3049  C CD1 . TYR A 1 554 ? 110.739 98.198  128.026 1.00 50.09  ? 553 TYR A CD1 1 
ATOM   3050  C CD2 . TYR A 1 554 ? 110.562 99.126  130.217 1.00 78.95  ? 553 TYR A CD2 1 
ATOM   3051  C CE1 . TYR A 1 554 ? 109.654 97.392  128.278 1.00 57.79  ? 553 TYR A CE1 1 
ATOM   3052  C CE2 . TYR A 1 554 ? 109.464 98.330  130.489 1.00 77.49  ? 553 TYR A CE2 1 
ATOM   3053  C CZ  . TYR A 1 554 ? 109.028 97.452  129.510 1.00 64.01  ? 553 TYR A CZ  1 
ATOM   3054  O OH  . TYR A 1 554 ? 107.957 96.654  129.710 1.00 52.87  ? 553 TYR A OH  1 
ATOM   3055  N N   . ILE A 1 555 ? 112.565 100.981 125.865 1.00 92.90  ? 554 ILE A N   1 
ATOM   3056  C CA  . ILE A 1 555 ? 112.360 100.807 124.444 1.00 67.10  ? 554 ILE A CA  1 
ATOM   3057  C C   . ILE A 1 555 ? 112.829 99.422  124.066 1.00 77.93  ? 554 ILE A C   1 
ATOM   3058  O O   . ILE A 1 555 ? 113.935 99.029  124.445 1.00 81.50  ? 554 ILE A O   1 
ATOM   3059  C CB  . ILE A 1 555 ? 113.159 101.833 123.713 1.00 64.70  ? 554 ILE A CB  1 
ATOM   3060  C CG1 . ILE A 1 555 ? 112.524 103.194 123.922 1.00 94.16  ? 554 ILE A CG1 1 
ATOM   3061  C CG2 . ILE A 1 555 ? 113.146 101.470 122.280 1.00 102.41 ? 554 ILE A CG2 1 
ATOM   3062  C CD1 . ILE A 1 555 ? 113.573 104.272 123.651 1.00 164.03 ? 554 ILE A CD1 1 
ATOM   3063  N N   . ARG A 1 556 ? 111.957 98.711  123.338 1.00 66.34  ? 555 ARG A N   1 
ATOM   3064  C CA  . ARG A 1 556 ? 112.323 97.458  122.721 1.00 68.97  ? 555 ARG A CA  1 
ATOM   3065  C C   . ARG A 1 556 ? 112.609 97.809  121.276 1.00 88.75  ? 555 ARG A C   1 
ATOM   3066  O O   . ARG A 1 556 ? 111.820 98.540  120.650 1.00 68.82  ? 555 ARG A O   1 
ATOM   3067  C CB  . ARG A 1 556 ? 111.179 96.443  122.729 1.00 71.59  ? 555 ARG A CB  1 
ATOM   3068  C CG  . ARG A 1 556 ? 110.740 95.910  124.058 1.00 65.50  ? 555 ARG A CG  1 
ATOM   3069  C CD  . ARG A 1 556 ? 111.941 95.369  124.781 1.00 55.54  ? 555 ARG A CD  1 
ATOM   3070  N NE  . ARG A 1 556 ? 112.458 94.237  124.124 1.00 49.77  ? 555 ARG A NE  1 
ATOM   3071  C CZ  . ARG A 1 556 ? 111.978 92.998  124.190 1.00 55.34  ? 555 ARG A CZ  1 
ATOM   3072  N NH1 . ARG A 1 556 ? 112.701 91.979  123.697 1.00 74.44  ? 555 ARG A NH1 1 
ATOM   3073  N NH2 . ARG A 1 556 ? 110.789 92.749  124.718 1.00 51.42  ? 555 ARG A NH2 1 
ATOM   3074  N N   . HIS A 1 557 ? 113.713 97.277  120.744 1.00 74.13  ? 556 HIS A N   1 
ATOM   3075  C CA  . HIS A 1 557 ? 113.963 97.525  119.350 1.00 78.96  ? 556 HIS A CA  1 
ATOM   3076  C C   . HIS A 1 557 ? 114.705 96.367  118.742 1.00 103.09 ? 556 HIS A C   1 
ATOM   3077  O O   . HIS A 1 557 ? 115.441 95.731  119.480 1.00 116.56 ? 556 HIS A O   1 
ATOM   3078  C CB  . HIS A 1 557 ? 114.791 98.796  119.155 1.00 102.75 ? 556 HIS A CB  1 
ATOM   3079  C CG  . HIS A 1 557 ? 116.100 98.873  119.863 1.00 104.24 ? 556 HIS A CG  1 
ATOM   3080  N ND1 . HIS A 1 557 ? 117.234 98.183  119.532 1.00 139.42 ? 556 HIS A ND1 1 
ATOM   3081  C CD2 . HIS A 1 557 ? 116.423 99.612  120.899 1.00 123.98 ? 556 HIS A CD2 1 
ATOM   3082  C CE1 . HIS A 1 557 ? 118.198 98.532  120.393 1.00 157.18 ? 556 HIS A CE1 1 
ATOM   3083  N NE2 . HIS A 1 557 ? 117.713 99.388  121.211 1.00 147.13 ? 556 HIS A NE2 1 
ATOM   3084  N N   . TRP A 1 558 ? 114.534 96.134  117.422 1.00 117.19 ? 557 TRP A N   1 
ATOM   3085  C CA  . TRP A 1 558 ? 115.321 95.114  116.730 1.00 136.27 ? 557 TRP A CA  1 
ATOM   3086  C C   . TRP A 1 558 ? 116.449 95.763  115.934 1.00 149.97 ? 557 TRP A C   1 
ATOM   3087  O O   . TRP A 1 558 ? 117.322 96.367  116.563 1.00 208.22 ? 557 TRP A O   1 
ATOM   3088  C CB  . TRP A 1 558 ? 114.425 94.184  115.916 1.00 100.99 ? 557 TRP A CB  1 
ATOM   3089  C CG  . TRP A 1 558 ? 115.139 93.040  115.239 1.00 91.96  ? 557 TRP A CG  1 
ATOM   3090  C CD1 . TRP A 1 558 ? 114.897 92.558  113.977 1.00 160.55 ? 557 TRP A CD1 1 
ATOM   3091  C CD2 . TRP A 1 558 ? 116.174 92.223  115.785 1.00 66.84  ? 557 TRP A CD2 1 
ATOM   3092  N NE1 . TRP A 1 558 ? 115.713 91.484  113.727 1.00 117.30 ? 557 TRP A NE1 1 
ATOM   3093  C CE2 . TRP A 1 558 ? 116.495 91.268  114.837 1.00 78.81  ? 557 TRP A CE2 1 
ATOM   3094  C CE3 . TRP A 1 558 ? 116.819 92.167  117.008 1.00 152.22 ? 557 TRP A CE3 1 
ATOM   3095  C CZ2 . TRP A 1 558 ? 117.434 90.281  115.067 1.00 124.57 ? 557 TRP A CZ2 1 
ATOM   3096  C CZ3 . TRP A 1 558 ? 117.753 91.186  117.232 1.00 141.02 ? 557 TRP A CZ3 1 
ATOM   3097  C CH2 . TRP A 1 558 ? 118.048 90.255  116.280 1.00 117.96 ? 557 TRP A CH2 1 
ATOM   3098  N N   . ASP A 1 559 ? 116.434 95.642  114.596 1.00 124.10 ? 558 ASP A N   1 
ATOM   3099  C CA  . ASP A 1 559 ? 117.464 96.244  113.772 1.00 165.46 ? 558 ASP A CA  1 
ATOM   3100  C C   . ASP A 1 559 ? 116.816 97.455  113.127 1.00 155.49 ? 558 ASP A C   1 
ATOM   3101  O O   . ASP A 1 559 ? 117.245 98.591  113.400 1.00 259.67 ? 558 ASP A O   1 
ATOM   3102  C CB  . ASP A 1 559 ? 118.142 95.284  112.766 1.00 195.07 ? 558 ASP A CB  1 
ATOM   3103  C CG  . ASP A 1 559 ? 117.214 94.232  112.202 1.00 204.33 ? 558 ASP A CG  1 
ATOM   3104  O OD1 . ASP A 1 559 ? 116.062 94.604  111.785 1.00 206.39 ? 558 ASP A OD1 1 
ATOM   3105  O OD2 . ASP A 1 559 ? 117.609 93.058  112.184 1.00 233.89 ? 558 ASP A OD2 1 
ATOM   3106  N N   . GLN A 1 560 ? 115.834 97.205  112.240 1.00 123.41 ? 559 GLN A N   1 
ATOM   3107  C CA  . GLN A 1 560 ? 115.225 98.291  111.474 1.00 148.73 ? 559 GLN A CA  1 
ATOM   3108  C C   . GLN A 1 560 ? 113.719 98.210  111.547 1.00 131.72 ? 559 GLN A C   1 
ATOM   3109  O O   . GLN A 1 560 ? 113.045 99.074  110.943 1.00 129.11 ? 559 GLN A O   1 
ATOM   3110  C CB  . GLN A 1 560 ? 115.698 98.379  110.010 1.00 171.50 ? 559 GLN A CB  1 
ATOM   3111  C CG  . GLN A 1 560 ? 117.225 98.532  109.894 1.00 240.67 ? 559 GLN A CG  1 
ATOM   3112  C CD  . GLN A 1 560 ? 117.789 98.802  108.514 1.00 202.21 ? 559 GLN A CD  1 
ATOM   3113  O OE1 . GLN A 1 560 ? 117.125 99.391  107.659 1.00 196.64 ? 559 GLN A OE1 1 
ATOM   3114  N NE2 . GLN A 1 560 ? 119.031 98.372  108.293 1.00 184.22 ? 559 GLN A NE2 1 
ATOM   3115  N N   . ASN A 1 561 ? 113.211 97.225  112.316 1.00 111.37 ? 560 ASN A N   1 
ATOM   3116  C CA  . ASN A 1 561 ? 111.763 97.065  112.385 1.00 138.27 ? 560 ASN A CA  1 
ATOM   3117  C C   . ASN A 1 561 ? 111.177 98.226  113.215 1.00 131.86 ? 560 ASN A C   1 
ATOM   3118  O O   . ASN A 1 561 ? 111.904 99.078  113.687 1.00 118.84 ? 560 ASN A O   1 
ATOM   3119  C CB  . ASN A 1 561 ? 111.395 95.629  112.819 1.00 92.57  ? 560 ASN A CB  1 
ATOM   3120  C CG  . ASN A 1 561 ? 111.878 94.502  111.916 1.00 151.90 ? 560 ASN A CG  1 
ATOM   3121  O OD1 . ASN A 1 561 ? 111.894 93.355  112.323 1.00 118.95 ? 560 ASN A OD1 1 
ATOM   3122  N ND2 . ASN A 1 561 ? 112.261 94.771  110.679 1.00 234.19 ? 560 ASN A ND2 1 
ATOM   3123  N N   . GLU A 1 562 ? 109.845 98.241  113.381 1.00 156.91 ? 561 GLU A N   1 
ATOM   3124  C CA  . GLU A 1 562 ? 109.125 99.033  114.380 1.00 138.90 ? 561 GLU A CA  1 
ATOM   3125  C C   . GLU A 1 562 ? 109.707 98.937  115.798 1.00 139.25 ? 561 GLU A C   1 
ATOM   3126  O O   . GLU A 1 562 ? 110.079 97.866  116.263 1.00 120.51 ? 561 GLU A O   1 
ATOM   3127  C CB  . GLU A 1 562 ? 107.664 98.588  114.547 1.00 175.10 ? 561 GLU A CB  1 
ATOM   3128  C CG  . GLU A 1 562 ? 106.725 99.754  114.819 1.00 208.20 ? 561 GLU A CG  1 
ATOM   3129  C CD  . GLU A 1 562 ? 106.295 100.549 113.590 1.00 305.03 ? 561 GLU A CD  1 
ATOM   3130  O OE1 . GLU A 1 562 ? 107.147 100.823 112.698 1.00 385.32 ? 561 GLU A OE1 1 
ATOM   3131  O OE2 . GLU A 1 562 ? 105.094 100.900 113.512 1.00 277.27 ? 561 GLU A OE2 1 
ATOM   3132  N N   . ARG A 1 563 ? 109.775 100.097 116.491 1.00 129.80 ? 562 ARG A N   1 
ATOM   3133  C CA  . ARG A 1 563 ? 110.449 100.272 117.790 1.00 80.79  ? 562 ARG A CA  1 
ATOM   3134  C C   . ARG A 1 563 ? 109.329 100.557 118.745 1.00 73.63  ? 562 ARG A C   1 
ATOM   3135  O O   . ARG A 1 563 ? 108.432 101.275 118.385 1.00 91.40  ? 562 ARG A O   1 
ATOM   3136  C CB  . ARG A 1 563 ? 111.610 101.283 117.702 1.00 70.11  ? 562 ARG A CB  1 
ATOM   3137  C CG  . ARG A 1 563 ? 112.622 100.859 116.628 1.00 110.02 ? 562 ARG A CG  1 
ATOM   3138  C CD  . ARG A 1 563 ? 114.098 101.139 116.611 1.00 104.69 ? 562 ARG A CD  1 
ATOM   3139  N NE  . ARG A 1 563 ? 114.305 102.564 116.702 1.00 153.84 ? 562 ARG A NE  1 
ATOM   3140  C CZ  . ARG A 1 563 ? 115.491 103.120 116.866 1.00 227.85 ? 562 ARG A CZ  1 
ATOM   3141  N NH1 . ARG A 1 563 ? 115.618 104.423 116.694 1.00 253.07 ? 562 ARG A NH1 1 
ATOM   3142  N NH2 . ARG A 1 563 ? 116.546 102.368 117.164 1.00 226.80 ? 562 ARG A NH2 1 
ATOM   3143  N N   . PHE A 1 564 ? 109.352 99.962  119.939 1.00 93.47  ? 563 PHE A N   1 
ATOM   3144  C CA  . PHE A 1 564 ? 108.246 100.074 120.875 1.00 90.23  ? 563 PHE A CA  1 
ATOM   3145  C C   . PHE A 1 564 ? 108.766 100.677 122.157 1.00 89.42  ? 563 PHE A C   1 
ATOM   3146  O O   . PHE A 1 564 ? 109.695 100.127 122.757 1.00 101.11 ? 563 PHE A O   1 
ATOM   3147  C CB  . PHE A 1 564 ? 107.678 98.731  121.288 1.00 104.03 ? 563 PHE A CB  1 
ATOM   3148  C CG  . PHE A 1 564 ? 106.904 98.035  120.220 1.00 102.98 ? 563 PHE A CG  1 
ATOM   3149  C CD1 . PHE A 1 564 ? 107.560 97.452  119.171 1.00 131.40 ? 563 PHE A CD1 1 
ATOM   3150  C CD2 . PHE A 1 564 ? 105.543 97.965  120.275 1.00 91.20  ? 563 PHE A CD2 1 
ATOM   3151  C CE1 . PHE A 1 564 ? 106.858 96.790  118.191 1.00 169.00 ? 563 PHE A CE1 1 
ATOM   3152  C CE2 . PHE A 1 564 ? 104.835 97.298  119.319 1.00 95.48  ? 563 PHE A CE2 1 
ATOM   3153  C CZ  . PHE A 1 564 ? 105.484 96.719  118.266 1.00 189.63 ? 563 PHE A CZ  1 
ATOM   3154  N N   . LEU A 1 565 ? 108.141 101.774 122.553 1.00 71.34  ? 564 LEU A N   1 
ATOM   3155  C CA  . LEU A 1 565 ? 108.433 102.418 123.815 1.00 85.67  ? 564 LEU A CA  1 
ATOM   3156  C C   . LEU A 1 565 ? 107.306 102.061 124.783 1.00 63.47  ? 564 LEU A C   1 
ATOM   3157  O O   . LEU A 1 565 ? 106.178 102.279 124.434 1.00 43.66  ? 564 LEU A O   1 
ATOM   3158  C CB  . LEU A 1 565 ? 108.488 103.916 123.577 1.00 85.41  ? 564 LEU A CB  1 
ATOM   3159  C CG  . LEU A 1 565 ? 108.170 104.796 124.756 1.00 68.20  ? 564 LEU A CG  1 
ATOM   3160  C CD1 . LEU A 1 565 ? 109.376 104.689 125.700 1.00 74.28  ? 564 LEU A CD1 1 
ATOM   3161  C CD2 . LEU A 1 565 ? 107.897 106.191 124.259 1.00 73.91  ? 564 LEU A CD2 1 
ATOM   3162  N N   . VAL A 1 566 ? 107.657 101.510 125.961 1.00 59.54  ? 565 VAL A N   1 
ATOM   3163  C CA  . VAL A 1 566 ? 106.719 101.130 126.983 1.00 54.18  ? 565 VAL A CA  1 
ATOM   3164  C C   . VAL A 1 566 ? 106.914 102.093 128.132 1.00 73.28  ? 565 VAL A C   1 
ATOM   3165  O O   . VAL A 1 566 ? 108.041 102.407 128.494 1.00 78.31  ? 565 VAL A O   1 
ATOM   3166  C CB  . VAL A 1 566 ? 106.962 99.713  127.477 1.00 62.96  ? 565 VAL A CB  1 
ATOM   3167  C CG1 . VAL A 1 566 ? 105.867 99.373  128.485 1.00 91.80  ? 565 VAL A CG1 1 
ATOM   3168  C CG2 . VAL A 1 566 ? 106.982 98.691  126.359 1.00 72.23  ? 565 VAL A CG2 1 
ATOM   3169  N N   . VAL A 1 567 ? 105.805 102.567 128.691 1.00 76.53  ? 566 VAL A N   1 
ATOM   3170  C CA  . VAL A 1 567 ? 105.889 103.559 129.739 1.00 60.33  ? 566 VAL A CA  1 
ATOM   3171  C C   . VAL A 1 567 ? 104.946 103.121 130.834 1.00 54.94  ? 566 VAL A C   1 
ATOM   3172  O O   . VAL A 1 567 ? 103.754 103.229 130.634 1.00 71.22  ? 566 VAL A O   1 
ATOM   3173  C CB  . VAL A 1 567 ? 105.526 104.948 129.219 1.00 59.50  ? 566 VAL A CB  1 
ATOM   3174  C CG1 . VAL A 1 567 ? 105.824 105.970 130.299 1.00 56.66  ? 566 VAL A CG1 1 
ATOM   3175  C CG2 . VAL A 1 567 ? 106.227 105.260 127.915 1.00 70.48  ? 566 VAL A CG2 1 
ATOM   3176  N N   . LEU A 1 568 ? 105.501 102.646 131.947 1.00 46.49  ? 567 LEU A N   1 
ATOM   3177  C CA  . LEU A 1 568 ? 104.671 102.172 133.030 1.00 58.26  ? 567 LEU A CA  1 
ATOM   3178  C C   . LEU A 1 568 ? 104.669 103.160 134.182 1.00 58.32  ? 567 LEU A C   1 
ATOM   3179  O O   . LEU A 1 568 ? 105.735 103.410 134.689 1.00 43.45  ? 567 LEU A O   1 
ATOM   3180  C CB  . LEU A 1 568 ? 105.193 100.816 133.469 1.00 53.67  ? 567 LEU A CB  1 
ATOM   3181  C CG  . LEU A 1 568 ? 105.235 99.806  132.333 1.00 64.55  ? 567 LEU A CG  1 
ATOM   3182  C CD1 . LEU A 1 568 ? 106.247 98.723  132.707 1.00 51.82  ? 567 LEU A CD1 1 
ATOM   3183  C CD2 . LEU A 1 568 ? 103.827 99.268  131.998 1.00 73.06  ? 567 LEU A CD2 1 
ATOM   3184  N N   . ASN A 1 569 ? 103.498 103.696 134.581 1.00 59.35  ? 568 ASN A N   1 
ATOM   3185  C CA  . ASN A 1 569 ? 103.517 104.678 135.632 1.00 69.56  ? 568 ASN A CA  1 
ATOM   3186  C C   . ASN A 1 569 ? 103.248 103.980 136.922 1.00 55.68  ? 568 ASN A C   1 
ATOM   3187  O O   . ASN A 1 569 ? 102.102 103.932 137.290 1.00 62.22  ? 568 ASN A O   1 
ATOM   3188  C CB  . ASN A 1 569 ? 102.520 105.814 135.469 1.00 76.58  ? 568 ASN A CB  1 
ATOM   3189  C CG  . ASN A 1 569 ? 102.561 106.855 136.599 1.00 74.69  ? 568 ASN A CG  1 
ATOM   3190  O OD1 . ASN A 1 569 ? 103.482 106.986 137.377 1.00 58.10  ? 568 ASN A OD1 1 
ATOM   3191  N ND2 . ASN A 1 569 ? 101.536 107.663 136.727 1.00 85.15  ? 568 ASN A ND2 1 
ATOM   3192  N N   . PHE A 1 570 ? 104.287 103.493 137.587 1.00 50.08  ? 569 PHE A N   1 
ATOM   3193  C CA  . PHE A 1 570 ? 104.044 102.694 138.761 1.00 63.35  ? 569 PHE A CA  1 
ATOM   3194  C C   . PHE A 1 570 ? 103.589 103.515 139.959 1.00 82.24  ? 569 PHE A C   1 
ATOM   3195  O O   . PHE A 1 570 ? 102.719 103.053 140.695 1.00 103.69 ? 569 PHE A O   1 
ATOM   3196  C CB  . PHE A 1 570 ? 105.246 101.837 139.115 1.00 66.30  ? 569 PHE A CB  1 
ATOM   3197  C CG  . PHE A 1 570 ? 105.288 100.558 138.323 1.00 75.24  ? 569 PHE A CG  1 
ATOM   3198  C CD1 . PHE A 1 570 ? 104.395 99.551  138.563 1.00 74.32  ? 569 PHE A CD1 1 
ATOM   3199  C CD2 . PHE A 1 570 ? 106.247 100.341 137.365 1.00 104.85 ? 569 PHE A CD2 1 
ATOM   3200  C CE1 . PHE A 1 570 ? 104.474 98.387  137.844 1.00 76.76  ? 569 PHE A CE1 1 
ATOM   3201  C CE2 . PHE A 1 570 ? 106.300 99.174  136.637 1.00 64.26  ? 569 PHE A CE2 1 
ATOM   3202  C CZ  . PHE A 1 570 ? 105.412 98.217  136.862 1.00 69.85  ? 569 PHE A CZ  1 
ATOM   3203  N N   . GLY A 1 571 ? 104.141 104.687 140.185 1.00 86.37  ? 570 GLY A N   1 
ATOM   3204  C CA  . GLY A 1 571 ? 103.645 105.502 141.284 1.00 123.44 ? 570 GLY A CA  1 
ATOM   3205  C C   . GLY A 1 571 ? 102.187 105.984 141.112 1.00 90.81  ? 570 GLY A C   1 
ATOM   3206  O O   . GLY A 1 571 ? 101.754 106.139 139.974 1.00 56.93  ? 570 GLY A O   1 
ATOM   3207  N N   . ASP A 1 572 ? 101.505 106.267 142.267 1.00 71.44  ? 571 ASP A N   1 
ATOM   3208  C CA  . ASP A 1 572 ? 100.106 106.669 142.377 1.00 71.72  ? 571 ASP A CA  1 
ATOM   3209  C C   . ASP A 1 572 ? 99.807  108.129 141.967 1.00 70.83  ? 571 ASP A C   1 
ATOM   3210  O O   . ASP A 1 572 ? 98.716  108.637 142.223 1.00 75.85  ? 571 ASP A O   1 
ATOM   3211  C CB  . ASP A 1 572 ? 99.574  106.419 143.802 1.00 85.83  ? 571 ASP A CB  1 
ATOM   3212  C CG  . ASP A 1 572 ? 100.217 107.302 144.861 1.00 132.02 ? 571 ASP A CG  1 
ATOM   3213  O OD1 . ASP A 1 572 ? 101.320 106.967 145.159 1.00 203.51 ? 571 ASP A OD1 1 
ATOM   3214  O OD2 . ASP A 1 572 ? 99.637  108.308 145.352 1.00 158.57 ? 571 ASP A OD2 1 
ATOM   3215  N N   . VAL A 1 573 ? 100.718 108.825 141.310 1.00 76.69  ? 572 VAL A N   1 
ATOM   3216  C CA  . VAL A 1 573 ? 100.509 110.208 141.017 1.00 57.51  ? 572 VAL A CA  1 
ATOM   3217  C C   . VAL A 1 573 ? 100.653 110.390 139.543 1.00 59.72  ? 572 VAL A C   1 
ATOM   3218  O O   . VAL A 1 573 ? 101.687 109.931 138.996 1.00 58.96  ? 572 VAL A O   1 
ATOM   3219  C CB  . VAL A 1 573 ? 101.628 111.014 141.636 1.00 78.66  ? 572 VAL A CB  1 
ATOM   3220  C CG1 . VAL A 1 573 ? 100.971 112.414 141.742 1.00 94.67  ? 572 VAL A CG1 1 
ATOM   3221  C CG2 . VAL A 1 573 ? 102.253 110.345 142.917 1.00 72.91  ? 572 VAL A CG2 1 
ATOM   3222  N N   . GLY A 1 574 ? 99.684  111.066 138.942 1.00 50.10  ? 573 GLY A N   1 
ATOM   3223  C CA  . GLY A 1 574 ? 99.786  111.277 137.505 1.00 72.88  ? 573 GLY A CA  1 
ATOM   3224  C C   . GLY A 1 574 ? 100.925 112.220 137.081 1.00 68.32  ? 573 GLY A C   1 
ATOM   3225  O O   . GLY A 1 574 ? 101.311 113.083 137.875 1.00 54.89  ? 573 GLY A O   1 
ATOM   3226  N N   . LEU A 1 575 ? 101.432 112.051 135.829 1.00 77.07  ? 574 LEU A N   1 
ATOM   3227  C CA  . LEU A 1 575 ? 102.399 112.979 135.260 1.00 72.95  ? 574 LEU A CA  1 
ATOM   3228  C C   . LEU A 1 575 ? 101.736 113.924 134.288 1.00 85.32  ? 574 LEU A C   1 
ATOM   3229  O O   . LEU A 1 575 ? 100.842 113.546 133.539 1.00 139.52 ? 574 LEU A O   1 
ATOM   3230  C CB  . LEU A 1 575 ? 103.543 112.229 134.616 1.00 60.10  ? 574 LEU A CB  1 
ATOM   3231  C CG  . LEU A 1 575 ? 104.307 111.390 135.662 1.00 86.24  ? 574 LEU A CG  1 
ATOM   3232  C CD1 . LEU A 1 575 ? 105.599 110.945 135.112 1.00 116.14 ? 574 LEU A CD1 1 
ATOM   3233  C CD2 . LEU A 1 575 ? 104.605 112.098 136.969 1.00 73.30  ? 574 LEU A CD2 1 
ATOM   3234  N N   . SER A 1 576 ? 102.200 115.176 134.323 1.00 80.19  ? 575 SER A N   1 
ATOM   3235  C CA  . SER A 1 576 ? 101.457 116.243 133.695 1.00 86.91  ? 575 SER A CA  1 
ATOM   3236  C C   . SER A 1 576 ? 102.335 117.035 132.702 1.00 84.45  ? 575 SER A C   1 
ATOM   3237  O O   . SER A 1 576 ? 101.936 118.082 132.187 1.00 117.81 ? 575 SER A O   1 
ATOM   3238  C CB  . SER A 1 576 ? 100.785 117.017 134.824 1.00 117.44 ? 575 SER A CB  1 
ATOM   3239  O OG  . SER A 1 576 ? 99.854  117.937 134.275 1.00 213.23 ? 575 SER A OG  1 
ATOM   3240  N N   . ALA A 1 577 ? 103.540 116.523 132.415 1.00 78.87  ? 576 ALA A N   1 
ATOM   3241  C CA  . ALA A 1 577 ? 104.606 117.351 131.859 1.00 101.29 ? 576 ALA A CA  1 
ATOM   3242  C C   . ALA A 1 577 ? 105.454 116.539 130.864 1.00 95.22  ? 576 ALA A C   1 
ATOM   3243  O O   . ALA A 1 577 ? 106.603 116.829 130.518 1.00 65.33  ? 576 ALA A O   1 
ATOM   3244  C CB  . ALA A 1 577 ? 105.371 117.968 133.035 1.00 81.65  ? 576 ALA A CB  1 
ATOM   3245  N N   . GLY A 1 578 ? 104.825 115.507 130.350 1.00 84.01  ? 577 GLY A N   1 
ATOM   3246  C CA  . GLY A 1 578 ? 105.470 114.766 129.313 1.00 106.54 ? 577 GLY A CA  1 
ATOM   3247  C C   . GLY A 1 578 ? 106.478 113.810 129.862 1.00 74.94  ? 577 GLY A C   1 
ATOM   3248  O O   . GLY A 1 578 ? 106.719 113.781 131.058 1.00 108.04 ? 577 GLY A O   1 
ATOM   3249  N N   . LEU A 1 579 ? 106.965 112.999 128.905 1.00 75.19  ? 578 LEU A N   1 
ATOM   3250  C CA  . LEU A 1 579 ? 108.221 112.306 129.029 1.00 87.31  ? 578 LEU A CA  1 
ATOM   3251  C C   . LEU A 1 579 ? 109.229 113.397 129.001 1.00 67.96  ? 578 LEU A C   1 
ATOM   3252  O O   . LEU A 1 579 ? 109.025 114.380 128.328 1.00 129.83 ? 578 LEU A O   1 
ATOM   3253  C CB  . LEU A 1 579 ? 108.467 111.246 127.953 1.00 85.73  ? 578 LEU A CB  1 
ATOM   3254  C CG  . LEU A 1 579 ? 107.748 109.913 128.297 1.00 85.92  ? 578 LEU A CG  1 
ATOM   3255  C CD1 . LEU A 1 579 ? 106.274 110.085 128.720 1.00 60.60  ? 578 LEU A CD1 1 
ATOM   3256  C CD2 . LEU A 1 579 ? 107.816 108.919 127.152 1.00 67.84  ? 578 LEU A CD2 1 
ATOM   3257  N N   . GLN A 1 580 ? 110.284 113.208 129.797 1.00 72.88  ? 579 GLN A N   1 
ATOM   3258  C CA  . GLN A 1 580 ? 111.450 114.034 129.637 1.00 98.21  ? 579 GLN A CA  1 
ATOM   3259  C C   . GLN A 1 580 ? 112.594 113.088 129.876 1.00 89.82  ? 579 GLN A C   1 
ATOM   3260  O O   . GLN A 1 580 ? 113.067 113.032 130.988 1.00 66.71  ? 579 GLN A O   1 
ATOM   3261  C CB  . GLN A 1 580 ? 111.350 115.338 130.441 1.00 92.05  ? 579 GLN A CB  1 
ATOM   3262  C CG  . GLN A 1 580 ? 110.241 115.399 131.478 1.00 81.01  ? 579 GLN A CG  1 
ATOM   3263  C CD  . GLN A 1 580 ? 110.161 116.717 132.257 1.00 109.02 ? 579 GLN A CD  1 
ATOM   3264  O OE1 . GLN A 1 580 ? 109.105 117.168 132.683 1.00 56.66  ? 579 GLN A OE1 1 
ATOM   3265  N NE2 . GLN A 1 580 ? 111.300 117.370 132.489 1.00 116.59 ? 579 GLN A NE2 1 
ATOM   3266  N N   . ALA A 1 581 ? 112.967 112.390 128.775 1.00 104.21 ? 580 ALA A N   1 
ATOM   3267  C CA  . ALA A 1 581 ? 114.055 111.425 128.726 1.00 110.53 ? 580 ALA A CA  1 
ATOM   3268  C C   . ALA A 1 581 ? 115.396 112.118 128.777 1.00 140.59 ? 580 ALA A C   1 
ATOM   3269  O O   . ALA A 1 581 ? 115.741 112.839 127.840 1.00 132.92 ? 580 ALA A O   1 
ATOM   3270  C CB  . ALA A 1 581 ? 113.982 110.666 127.448 1.00 205.98 ? 580 ALA A CB  1 
ATOM   3271  N N   . SER A 1 582 ? 116.133 111.905 129.871 1.00 205.79 ? 581 SER A N   1 
ATOM   3272  C CA  . SER A 1 582 ? 117.542 112.263 129.911 1.00 223.18 ? 581 SER A CA  1 
ATOM   3273  C C   . SER A 1 582 ? 118.310 111.089 129.335 1.00 230.37 ? 581 SER A C   1 
ATOM   3274  O O   . SER A 1 582 ? 118.008 109.945 129.733 1.00 194.85 ? 581 SER A O   1 
ATOM   3275  C CB  . SER A 1 582 ? 117.988 112.584 131.323 1.00 318.48 ? 581 SER A CB  1 
ATOM   3276  O OG  . SER A 1 582 ? 119.397 112.745 131.411 1.00 358.74 ? 581 SER A OG  1 
ATOM   3277  N N   . ASP A 1 583 ? 119.264 111.394 128.422 1.00 235.68 ? 582 ASP A N   1 
ATOM   3278  C CA  . ASP A 1 583 ? 120.434 110.557 128.164 1.00 329.24 ? 582 ASP A CA  1 
ATOM   3279  C C   . ASP A 1 583 ? 120.026 109.213 127.558 1.00 306.67 ? 582 ASP A C   1 
ATOM   3280  O O   . ASP A 1 583 ? 120.304 108.136 128.122 1.00 375.82 ? 582 ASP A O   1 
ATOM   3281  C CB  . ASP A 1 583 ? 121.274 110.366 129.438 1.00 450.31 ? 582 ASP A CB  1 
ATOM   3282  C CG  . ASP A 1 583 ? 122.588 109.615 129.255 1.00 498.71 ? 582 ASP A CG  1 
ATOM   3283  O OD1 . ASP A 1 583 ? 123.077 109.525 128.107 1.00 490.44 ? 582 ASP A OD1 1 
ATOM   3284  O OD2 . ASP A 1 583 ? 123.106 109.114 130.268 1.00 546.88 ? 582 ASP A OD2 1 
ATOM   3285  N N   . LEU A 1 584 ? 119.370 109.297 126.398 1.00 198.06 ? 583 LEU A N   1 
ATOM   3286  C CA  . LEU A 1 584 ? 119.031 108.089 125.658 1.00 186.40 ? 583 LEU A CA  1 
ATOM   3287  C C   . LEU A 1 584 ? 120.269 107.544 124.961 1.00 256.16 ? 583 LEU A C   1 
ATOM   3288  O O   . LEU A 1 584 ? 121.113 108.340 124.538 1.00 229.73 ? 583 LEU A O   1 
ATOM   3289  C CB  . LEU A 1 584 ? 117.937 108.394 124.650 1.00 168.19 ? 583 LEU A CB  1 
ATOM   3290  C CG  . LEU A 1 584 ? 116.560 108.498 125.310 1.00 167.12 ? 583 LEU A CG  1 
ATOM   3291  C CD1 . LEU A 1 584 ? 115.739 109.563 124.597 1.00 199.81 ? 583 LEU A CD1 1 
ATOM   3292  C CD2 . LEU A 1 584 ? 115.784 107.158 125.372 1.00 82.99  ? 583 LEU A CD2 1 
ATOM   3293  N N   . PRO A 1 585 ? 120.403 106.192 124.827 1.00 336.48 ? 584 PRO A N   1 
ATOM   3294  C CA  . PRO A 1 585 ? 121.398 105.611 123.920 1.00 314.34 ? 584 PRO A CA  1 
ATOM   3295  C C   . PRO A 1 585 ? 121.218 106.188 122.510 1.00 282.01 ? 584 PRO A C   1 
ATOM   3296  O O   . PRO A 1 585 ? 120.086 106.307 122.030 1.00 174.89 ? 584 PRO A O   1 
ATOM   3297  C CB  . PRO A 1 585 ? 121.142 104.089 123.962 1.00 344.18 ? 584 PRO A CB  1 
ATOM   3298  C CG  . PRO A 1 585 ? 120.278 103.834 125.203 1.00 330.79 ? 584 PRO A CG  1 
ATOM   3299  C CD  . PRO A 1 585 ? 119.615 105.152 125.531 1.00 343.40 ? 584 PRO A CD  1 
ATOM   3300  N N   . ALA A 1 586 ? 122.339 106.540 121.852 1.00 329.11 ? 585 ALA A N   1 
ATOM   3301  C CA  . ALA A 1 586 ? 122.310 107.352 120.638 1.00 340.32 ? 585 ALA A CA  1 
ATOM   3302  C C   . ALA A 1 586 ? 121.664 106.591 119.467 1.00 289.08 ? 585 ALA A C   1 
ATOM   3303  O O   . ALA A 1 586 ? 121.123 107.210 118.549 1.00 175.38 ? 585 ALA A O   1 
ATOM   3304  C CB  . ALA A 1 586 ? 123.715 107.813 120.313 1.00 367.16 ? 585 ALA A CB  1 
ATOM   3305  N N   . SER A 1 587 ? 121.730 105.249 119.519 1.00 282.55 ? 586 SER A N   1 
ATOM   3306  C CA  . SER A 1 587 ? 121.105 104.338 118.569 1.00 272.38 ? 586 SER A CA  1 
ATOM   3307  C C   . SER A 1 587 ? 119.580 104.278 118.675 1.00 268.62 ? 586 SER A C   1 
ATOM   3308  O O   . SER A 1 587 ? 118.949 103.828 117.720 1.00 224.62 ? 586 SER A O   1 
ATOM   3309  C CB  . SER A 1 587 ? 121.680 102.942 118.770 1.00 315.20 ? 586 SER A CB  1 
ATOM   3310  O OG  . SER A 1 587 ? 121.470 102.466 120.102 1.00 206.79 ? 586 SER A OG  1 
ATOM   3311  N N   . ALA A 1 588 ? 119.006 104.700 119.820 1.00 277.17 ? 587 ALA A N   1 
ATOM   3312  C CA  . ALA A 1 588 ? 117.631 104.380 120.190 1.00 207.96 ? 587 ALA A CA  1 
ATOM   3313  C C   . ALA A 1 588 ? 116.804 105.614 120.512 1.00 178.65 ? 587 ALA A C   1 
ATOM   3314  O O   . ALA A 1 588 ? 115.801 105.455 121.197 1.00 180.63 ? 587 ALA A O   1 
ATOM   3315  C CB  . ALA A 1 588 ? 117.637 103.451 121.364 1.00 197.88 ? 587 ALA A CB  1 
ATOM   3316  N N   . SER A 1 589 ? 117.207 106.794 120.003 1.00 208.81 ? 588 SER A N   1 
ATOM   3317  C CA  . SER A 1 589 ? 116.655 108.077 120.414 1.00 193.23 ? 588 SER A CA  1 
ATOM   3318  C C   . SER A 1 589 ? 115.141 108.086 120.216 1.00 145.79 ? 588 SER A C   1 
ATOM   3319  O O   . SER A 1 589 ? 114.609 107.566 119.228 1.00 145.31 ? 588 SER A O   1 
ATOM   3320  C CB  . SER A 1 589 ? 117.317 109.241 119.693 1.00 250.09 ? 588 SER A CB  1 
ATOM   3321  O OG  . SER A 1 589 ? 117.240 109.088 118.280 1.00 280.16 ? 588 SER A OG  1 
ATOM   3322  N N   . LEU A 1 590 ? 114.456 108.701 121.186 1.00 134.74 ? 589 LEU A N   1 
ATOM   3323  C CA  . LEU A 1 590 ? 113.027 108.872 121.114 1.00 131.61 ? 589 LEU A CA  1 
ATOM   3324  C C   . LEU A 1 590 ? 112.625 109.840 119.999 1.00 134.44 ? 589 LEU A C   1 
ATOM   3325  O O   . LEU A 1 590 ? 113.294 110.839 119.711 1.00 136.53 ? 589 LEU A O   1 
ATOM   3326  C CB  . LEU A 1 590 ? 112.510 109.481 122.410 1.00 143.50 ? 589 LEU A CB  1 
ATOM   3327  C CG  . LEU A 1 590 ? 112.337 108.581 123.622 1.00 109.84 ? 589 LEU A CG  1 
ATOM   3328  C CD1 . LEU A 1 590 ? 111.638 109.396 124.691 1.00 170.78 ? 589 LEU A CD1 1 
ATOM   3329  C CD2 . LEU A 1 590 ? 111.472 107.398 123.343 1.00 115.07 ? 589 LEU A CD2 1 
ATOM   3330  N N   . PRO A 1 591 ? 111.462 109.583 119.382 1.00 125.59 ? 590 PRO A N   1 
ATOM   3331  C CA  . PRO A 1 591 ? 110.911 110.500 118.393 1.00 169.14 ? 590 PRO A CA  1 
ATOM   3332  C C   . PRO A 1 591 ? 110.260 111.722 119.040 1.00 148.00 ? 590 PRO A C   1 
ATOM   3333  O O   . PRO A 1 591 ? 110.146 111.806 120.266 1.00 150.33 ? 590 PRO A O   1 
ATOM   3334  C CB  . PRO A 1 591 ? 109.882 109.574 117.726 1.00 189.85 ? 590 PRO A CB  1 
ATOM   3335  C CG  . PRO A 1 591 ? 109.338 108.787 118.893 1.00 131.45 ? 590 PRO A CG  1 
ATOM   3336  C CD  . PRO A 1 591 ? 110.595 108.414 119.627 1.00 114.93 ? 590 PRO A CD  1 
ATOM   3337  N N   . ALA A 1 592 ? 109.833 112.656 118.190 1.00 165.56 ? 591 ALA A N   1 
ATOM   3338  C CA  . ALA A 1 592 ? 108.984 113.753 118.617 1.00 215.16 ? 591 ALA A CA  1 
ATOM   3339  C C   . ALA A 1 592 ? 107.575 113.252 118.942 1.00 157.08 ? 591 ALA A C   1 
ATOM   3340  O O   . ALA A 1 592 ? 106.923 113.819 119.826 1.00 163.17 ? 591 ALA A O   1 
ATOM   3341  C CB  . ALA A 1 592 ? 108.960 114.818 117.546 1.00 286.60 ? 591 ALA A CB  1 
ATOM   3342  N N   . LYS A 1 593 ? 107.119 112.221 118.210 1.00 125.08 ? 592 LYS A N   1 
ATOM   3343  C CA  . LYS A 1 593 ? 105.787 111.641 118.362 1.00 143.55 ? 592 LYS A CA  1 
ATOM   3344  C C   . LYS A 1 593 ? 105.805 110.169 117.975 1.00 152.37 ? 592 LYS A C   1 
ATOM   3345  O O   . LYS A 1 593 ? 106.671 109.728 117.214 1.00 211.58 ? 592 LYS A O   1 
ATOM   3346  C CB  . LYS A 1 593 ? 104.710 112.214 117.428 1.00 186.76 ? 592 LYS A CB  1 
ATOM   3347  C CG  . LYS A 1 593 ? 104.483 113.713 117.446 1.00 224.23 ? 592 LYS A CG  1 
ATOM   3348  C CD  . LYS A 1 593 ? 103.166 114.073 116.756 1.00 206.02 ? 592 LYS A CD  1 
ATOM   3349  C CE  . LYS A 1 593 ? 103.027 115.563 116.524 1.00 312.90 ? 592 LYS A CE  1 
ATOM   3350  N NZ  . LYS A 1 593 ? 103.846 116.041 115.378 1.00 354.25 ? 592 LYS A NZ  1 
ATOM   3351  N N   . ALA A 1 594 ? 104.814 109.441 118.494 1.00 130.27 ? 593 ALA A N   1 
ATOM   3352  C CA  . ALA A 1 594 ? 104.762 107.985 118.407 1.00 168.46 ? 593 ALA A CA  1 
ATOM   3353  C C   . ALA A 1 594 ? 103.311 107.538 118.550 1.00 141.34 ? 593 ALA A C   1 
ATOM   3354  O O   . ALA A 1 594 ? 102.519 108.195 119.249 1.00 98.08  ? 593 ALA A O   1 
ATOM   3355  C CB  . ALA A 1 594 ? 105.631 107.333 119.481 1.00 166.65 ? 593 ALA A CB  1 
ATOM   3356  N N   . ASP A 1 595 ? 102.981 106.415 117.888 1.00 126.78 ? 594 ASP A N   1 
ATOM   3357  C CA  . ASP A 1 595 ? 101.599 105.980 117.689 1.00 136.89 ? 594 ASP A CA  1 
ATOM   3358  C C   . ASP A 1 595 ? 101.098 105.172 118.869 1.00 80.89  ? 594 ASP A C   1 
ATOM   3359  O O   . ASP A 1 595 ? 101.674 104.098 119.121 1.00 144.90 ? 594 ASP A O   1 
ATOM   3360  C CB  . ASP A 1 595 ? 101.476 105.085 116.452 1.00 259.79 ? 594 ASP A CB  1 
ATOM   3361  C CG  . ASP A 1 595 ? 101.897 105.711 115.126 1.00 395.80 ? 594 ASP A CG  1 
ATOM   3362  O OD1 . ASP A 1 595 ? 102.181 106.930 115.081 1.00 410.78 ? 594 ASP A OD1 1 
ATOM   3363  O OD2 . ASP A 1 595 ? 101.937 104.963 114.127 1.00 481.82 ? 594 ASP A OD2 1 
ATOM   3364  N N   . LEU A 1 596 ? 100.073 105.647 119.586 1.00 64.54  ? 595 LEU A N   1 
ATOM   3365  C CA  . LEU A 1 596 ? 99.577  104.893 120.750 1.00 103.11 ? 595 LEU A CA  1 
ATOM   3366  C C   . LEU A 1 596 ? 98.896  103.577 120.343 1.00 88.20  ? 595 LEU A C   1 
ATOM   3367  O O   . LEU A 1 596 ? 97.802  103.580 119.827 1.00 144.79 ? 595 LEU A O   1 
ATOM   3368  C CB  . LEU A 1 596 ? 98.610  105.735 121.581 1.00 99.66  ? 595 LEU A CB  1 
ATOM   3369  C CG  . LEU A 1 596 ? 97.818  105.041 122.693 1.00 100.88 ? 595 LEU A CG  1 
ATOM   3370  C CD1 . LEU A 1 596 ? 98.663  104.451 123.748 1.00 121.89 ? 595 LEU A CD1 1 
ATOM   3371  C CD2 . LEU A 1 596 ? 96.990  106.101 123.381 1.00 166.84 ? 595 LEU A CD2 1 
ATOM   3372  N N   . LEU A 1 597 ? 99.577  102.455 120.565 1.00 106.37 ? 596 LEU A N   1 
ATOM   3373  C CA  . LEU A 1 597 ? 99.107  101.132 120.203 1.00 107.57 ? 596 LEU A CA  1 
ATOM   3374  C C   . LEU A 1 597 ? 98.155  100.581 121.243 1.00 96.61  ? 596 LEU A C   1 
ATOM   3375  O O   . LEU A 1 597 ? 97.260  99.828  120.866 1.00 182.14 ? 596 LEU A O   1 
ATOM   3376  C CB  . LEU A 1 597 ? 100.305 100.216 120.064 1.00 124.33 ? 596 LEU A CB  1 
ATOM   3377  C CG  . LEU A 1 597 ? 100.002 98.791  119.660 1.00 152.79 ? 596 LEU A CG  1 
ATOM   3378  C CD1 . LEU A 1 597 ? 99.383  98.762  118.277 1.00 258.80 ? 596 LEU A CD1 1 
ATOM   3379  C CD2 . LEU A 1 597 ? 101.268 97.987  119.657 1.00 202.48 ? 596 LEU A CD2 1 
ATOM   3380  N N   . LEU A 1 598 ? 98.336  100.933 122.503 1.00 92.15  ? 597 LEU A N   1 
ATOM   3381  C CA  . LEU A 1 598 ? 97.308  100.724 123.493 1.00 106.74 ? 597 LEU A CA  1 
ATOM   3382  C C   . LEU A 1 598 ? 97.665  101.404 124.791 1.00 93.41  ? 597 LEU A C   1 
ATOM   3383  O O   . LEU A 1 598 ? 98.804  101.652 125.078 1.00 94.36  ? 597 LEU A O   1 
ATOM   3384  C CB  . LEU A 1 598 ? 97.123  99.237  123.784 1.00 115.14 ? 597 LEU A CB  1 
ATOM   3385  C CG  . LEU A 1 598 ? 98.117  98.547  124.701 1.00 107.45 ? 597 LEU A CG  1 
ATOM   3386  C CD1 . LEU A 1 598 ? 97.651  98.602  126.154 1.00 126.86 ? 597 LEU A CD1 1 
ATOM   3387  C CD2 . LEU A 1 598 ? 98.282  97.111  124.289 1.00 120.47 ? 597 LEU A CD2 1 
ATOM   3388  N N   . SER A 1 599 ? 96.657  101.689 125.583 1.00 105.00 ? 598 SER A N   1 
ATOM   3389  C CA  . SER A 1 599 ? 96.854  102.147 126.936 1.00 92.52  ? 598 SER A CA  1 
ATOM   3390  C C   . SER A 1 599 ? 96.076  101.195 127.830 1.00 94.83  ? 598 SER A C   1 
ATOM   3391  O O   . SER A 1 599 ? 95.053  100.637 127.473 1.00 119.40 ? 598 SER A O   1 
ATOM   3392  C CB  . SER A 1 599 ? 96.394  103.563 127.160 1.00 106.57 ? 598 SER A CB  1 
ATOM   3393  O OG  . SER A 1 599 ? 96.380  103.892 128.552 1.00 93.09  ? 598 SER A OG  1 
ATOM   3394  N N   . THR A 1 600 ? 96.616  101.046 129.021 1.00 111.21 ? 599 THR A N   1 
ATOM   3395  C CA  . THR A 1 600 ? 96.007  100.351 130.132 1.00 88.91  ? 599 THR A CA  1 
ATOM   3396  C C   . THR A 1 600 ? 94.718  101.059 130.541 1.00 123.56 ? 599 THR A C   1 
ATOM   3397  O O   . THR A 1 600 ? 93.924  100.455 131.249 1.00 124.20 ? 599 THR A O   1 
ATOM   3398  C CB  . THR A 1 600 ? 97.109  100.295 131.211 1.00 94.94  ? 599 THR A CB  1 
ATOM   3399  O OG1 . THR A 1 600 ? 97.844  99.135  130.836 1.00 65.81  ? 599 THR A OG1 1 
ATOM   3400  C CG2 . THR A 1 600 ? 96.690  100.284 132.669 1.00 144.42 ? 599 THR A CG2 1 
ATOM   3401  N N   . GLN A 1 601 ? 94.495  102.334 130.135 1.00 106.68 ? 600 GLN A N   1 
ATOM   3402  C CA  . GLN A 1 601 ? 93.291  103.018 130.576 1.00 158.93 ? 600 GLN A CA  1 
ATOM   3403  C C   . GLN A 1 601 ? 92.350  103.384 129.424 1.00 211.08 ? 600 GLN A C   1 
ATOM   3404  O O   . GLN A 1 601 ? 92.770  103.598 128.285 1.00 220.12 ? 600 GLN A O   1 
ATOM   3405  C CB  . GLN A 1 601 ? 93.695  104.219 131.418 1.00 147.96 ? 600 GLN A CB  1 
ATOM   3406  C CG  . GLN A 1 601 ? 94.108  103.828 132.827 1.00 167.96 ? 600 GLN A CG  1 
ATOM   3407  C CD  . GLN A 1 601 ? 93.899  104.925 133.853 1.00 223.12 ? 600 GLN A CD  1 
ATOM   3408  O OE1 . GLN A 1 601 ? 93.737  106.118 133.560 1.00 253.06 ? 600 GLN A OE1 1 
ATOM   3409  N NE2 . GLN A 1 601 ? 93.911  104.509 135.108 1.00 257.83 ? 600 GLN A NE2 1 
ATOM   3410  N N   . PRO A 1 602 ? 91.026  103.441 129.711 1.00 198.50 ? 601 PRO A N   1 
ATOM   3411  C CA  . PRO A 1 602 ? 90.068  103.958 128.738 1.00 201.84 ? 601 PRO A CA  1 
ATOM   3412  C C   . PRO A 1 602 ? 90.210  105.462 128.519 1.00 180.38 ? 601 PRO A C   1 
ATOM   3413  O O   . PRO A 1 602 ? 90.865  106.156 129.303 1.00 248.34 ? 601 PRO A O   1 
ATOM   3414  C CB  . PRO A 1 602 ? 88.720  103.620 129.386 1.00 247.54 ? 601 PRO A CB  1 
ATOM   3415  C CG  . PRO A 1 602 ? 89.014  103.641 130.869 1.00 221.59 ? 601 PRO A CG  1 
ATOM   3416  C CD  . PRO A 1 602 ? 90.375  103.005 130.966 1.00 180.00 ? 601 PRO A CD  1 
ATOM   3417  N N   . GLY A 1 603 ? 89.582  105.934 127.435 1.00 180.30 ? 602 GLY A N   1 
ATOM   3418  C CA  . GLY A 1 603 ? 89.476  107.354 127.141 1.00 221.72 ? 602 GLY A CA  1 
ATOM   3419  C C   . GLY A 1 603 ? 90.712  107.905 126.431 1.00 230.40 ? 602 GLY A C   1 
ATOM   3420  O O   . GLY A 1 603 ? 91.038  109.092 126.583 1.00 276.73 ? 602 GLY A O   1 
ATOM   3421  N N   . ARG A 1 604 ? 91.370  107.031 125.648 1.00 168.05 ? 603 ARG A N   1 
ATOM   3422  C CA  . ARG A 1 604 ? 92.545  107.392 124.869 1.00 170.62 ? 603 ARG A CA  1 
ATOM   3423  C C   . ARG A 1 604 ? 92.313  107.167 123.383 1.00 207.38 ? 603 ARG A C   1 
ATOM   3424  O O   . ARG A 1 604 ? 91.521  106.289 123.008 1.00 216.01 ? 603 ARG A O   1 
ATOM   3425  C CB  . ARG A 1 604 ? 93.710  106.509 125.291 1.00 195.14 ? 603 ARG A CB  1 
ATOM   3426  C CG  . ARG A 1 604 ? 94.324  106.885 126.625 1.00 215.33 ? 603 ARG A CG  1 
ATOM   3427  C CD  . ARG A 1 604 ? 95.128  108.146 126.452 1.00 206.10 ? 603 ARG A CD  1 
ATOM   3428  N NE  . ARG A 1 604 ? 95.757  108.471 127.707 1.00 213.45 ? 603 ARG A NE  1 
ATOM   3429  C CZ  . ARG A 1 604 ? 96.798  109.277 127.813 1.00 206.77 ? 603 ARG A CZ  1 
ATOM   3430  N NH1 . ARG A 1 604 ? 97.308  109.486 129.004 1.00 247.29 ? 603 ARG A NH1 1 
ATOM   3431  N NH2 . ARG A 1 604 ? 97.328  109.860 126.757 1.00 145.12 ? 603 ARG A NH2 1 
ATOM   3432  N N   . GLU A 1 605 ? 93.025  107.956 122.556 1.00 216.62 ? 604 GLU A N   1 
ATOM   3433  C CA  . GLU A 1 605 ? 92.779  107.989 121.117 1.00 287.12 ? 604 GLU A CA  1 
ATOM   3434  C C   . GLU A 1 605 ? 93.636  106.935 120.411 1.00 193.67 ? 604 GLU A C   1 
ATOM   3435  O O   . GLU A 1 605 ? 94.578  107.282 119.692 1.00 144.63 ? 604 GLU A O   1 
ATOM   3436  C CB  . GLU A 1 605 ? 93.032  109.399 120.571 1.00 378.32 ? 604 GLU A CB  1 
ATOM   3437  C CG  . GLU A 1 605 ? 91.994  110.410 121.047 1.00 420.92 ? 604 GLU A CG  1 
ATOM   3438  C CD  . GLU A 1 605 ? 92.104  111.802 120.445 1.00 508.45 ? 604 GLU A CD  1 
ATOM   3439  O OE1 . GLU A 1 605 ? 92.186  111.900 119.204 1.00 551.90 ? 604 GLU A OE1 1 
ATOM   3440  O OE2 . GLU A 1 605 ? 92.101  112.785 121.217 1.00 586.84 ? 604 GLU A OE2 1 
ATOM   3441  N N   . GLU A 1 606 ? 93.292  105.649 120.608 1.00 143.22 ? 605 GLU A N   1 
ATOM   3442  C CA  . GLU A 1 606 ? 94.205  104.572 120.249 1.00 172.87 ? 605 GLU A CA  1 
ATOM   3443  C C   . GLU A 1 606 ? 94.351  104.568 118.726 1.00 177.54 ? 605 GLU A C   1 
ATOM   3444  O O   . GLU A 1 606 ? 93.369  104.682 117.992 1.00 233.21 ? 605 GLU A O   1 
ATOM   3445  C CB  . GLU A 1 606 ? 93.790  103.212 120.828 1.00 211.34 ? 605 GLU A CB  1 
ATOM   3446  C CG  . GLU A 1 606 ? 93.737  103.227 122.350 1.00 292.21 ? 605 GLU A CG  1 
ATOM   3447  C CD  . GLU A 1 606 ? 93.709  101.890 123.084 1.00 325.56 ? 605 GLU A CD  1 
ATOM   3448  O OE1 . GLU A 1 606 ? 93.237  100.876 122.514 1.00 415.36 ? 605 GLU A OE1 1 
ATOM   3449  O OE2 . GLU A 1 606 ? 94.168  101.865 124.239 1.00 253.38 ? 605 GLU A OE2 1 
ATOM   3450  N N   . GLY A 1 607 ? 95.608  104.439 118.275 1.00 161.88 ? 606 GLY A N   1 
ATOM   3451  C CA  . GLY A 1 607 ? 95.975  104.602 116.883 1.00 115.23 ? 606 GLY A CA  1 
ATOM   3452  C C   . GLY A 1 607 ? 96.632  105.937 116.588 1.00 157.91 ? 606 GLY A C   1 
ATOM   3453  O O   . GLY A 1 607 ? 97.482  105.971 115.689 1.00 189.37 ? 606 GLY A O   1 
ATOM   3454  N N   . SER A 1 608 ? 96.234  107.009 117.309 1.00 166.88 ? 607 SER A N   1 
ATOM   3455  C CA  . SER A 1 608 ? 96.707  108.359 117.015 1.00 180.59 ? 607 SER A CA  1 
ATOM   3456  C C   . SER A 1 608 ? 98.151  108.570 117.480 1.00 173.01 ? 607 SER A C   1 
ATOM   3457  O O   . SER A 1 608 ? 98.611  107.946 118.451 1.00 249.52 ? 607 SER A O   1 
ATOM   3458  C CB  . SER A 1 608 ? 95.828  109.381 117.644 1.00 204.78 ? 607 SER A CB  1 
ATOM   3459  O OG  . SER A 1 608 ? 95.984  109.376 119.058 1.00 230.95 ? 607 SER A OG  1 
ATOM   3460  N N   . PRO A 1 609 ? 98.937  109.439 116.804 1.00 184.80 ? 608 PRO A N   1 
ATOM   3461  C CA  . PRO A 1 609 ? 100.230 109.898 117.328 1.00 258.01 ? 608 PRO A CA  1 
ATOM   3462  C C   . PRO A 1 609 ? 100.092 110.857 118.513 1.00 205.41 ? 608 PRO A C   1 
ATOM   3463  O O   . PRO A 1 609 ? 99.200  111.710 118.515 1.00 148.21 ? 608 PRO A O   1 
ATOM   3464  C CB  . PRO A 1 609 ? 100.913 110.576 116.129 1.00 251.99 ? 608 PRO A CB  1 
ATOM   3465  C CG  . PRO A 1 609 ? 99.765  111.009 115.272 1.00 272.84 ? 608 PRO A CG  1 
ATOM   3466  C CD  . PRO A 1 609 ? 98.661  109.989 115.483 1.00 194.63 ? 608 PRO A CD  1 
ATOM   3467  N N   . LEU A 1 610 ? 101.004 110.682 119.490 1.00 158.81 ? 609 LEU A N   1 
ATOM   3468  C CA  . LEU A 1 610 ? 101.084 111.461 120.715 1.00 163.33 ? 609 LEU A CA  1 
ATOM   3469  C C   . LEU A 1 610 ? 102.367 112.279 120.746 1.00 181.02 ? 609 LEU A C   1 
ATOM   3470  O O   . LEU A 1 610 ? 103.375 111.780 120.235 1.00 96.99  ? 609 LEU A O   1 
ATOM   3471  C CB  . LEU A 1 610 ? 101.127 110.488 121.882 1.00 131.76 ? 609 LEU A CB  1 
ATOM   3472  C CG  . LEU A 1 610 ? 99.835  109.788 122.227 1.00 159.77 ? 609 LEU A CG  1 
ATOM   3473  C CD1 . LEU A 1 610 ? 100.165 108.687 123.209 1.00 163.88 ? 609 LEU A CD1 1 
ATOM   3474  C CD2 . LEU A 1 610 ? 98.840  110.784 122.815 1.00 194.01 ? 609 LEU A CD2 1 
ATOM   3475  N N   . GLU A 1 611 ? 102.306 113.494 121.353 1.00 177.89 ? 610 GLU A N   1 
ATOM   3476  C CA  . GLU A 1 611 ? 103.477 114.329 121.595 1.00 148.45 ? 610 GLU A CA  1 
ATOM   3477  C C   . GLU A 1 611 ? 104.078 113.873 122.916 1.00 154.44 ? 610 GLU A C   1 
ATOM   3478  O O   . GLU A 1 611 ? 103.541 114.086 123.997 1.00 143.69 ? 610 GLU A O   1 
ATOM   3479  C CB  . GLU A 1 611 ? 103.195 115.833 121.664 1.00 205.55 ? 610 GLU A CB  1 
ATOM   3480  C CG  . GLU A 1 611 ? 102.662 116.403 120.360 1.00 358.95 ? 610 GLU A CG  1 
ATOM   3481  C CD  . GLU A 1 611 ? 101.205 116.102 120.018 1.00 505.30 ? 610 GLU A CD  1 
ATOM   3482  O OE1 . GLU A 1 611 ? 100.442 115.652 120.910 1.00 512.46 ? 610 GLU A OE1 1 
ATOM   3483  O OE2 . GLU A 1 611 ? 100.829 116.309 118.848 1.00 603.49 ? 610 GLU A OE2 1 
ATOM   3484  N N   . LEU A 1 612 ? 105.235 113.248 122.839 1.00 131.99 ? 611 LEU A N   1 
ATOM   3485  C CA  . LEU A 1 612 ? 105.890 112.754 124.023 1.00 94.08  ? 611 LEU A CA  1 
ATOM   3486  C C   . LEU A 1 612 ? 106.289 113.860 124.993 1.00 104.82 ? 611 LEU A C   1 
ATOM   3487  O O   . LEU A 1 612 ? 106.134 113.686 126.187 1.00 149.82 ? 611 LEU A O   1 
ATOM   3488  C CB  . LEU A 1 612 ? 107.148 112.024 123.527 1.00 123.91 ? 611 LEU A CB  1 
ATOM   3489  C CG  . LEU A 1 612 ? 106.872 110.695 122.810 1.00 109.86 ? 611 LEU A CG  1 
ATOM   3490  C CD1 . LEU A 1 612 ? 108.150 109.806 122.834 1.00 89.74  ? 611 LEU A CD1 1 
ATOM   3491  C CD2 . LEU A 1 612 ? 105.571 109.972 123.350 1.00 69.61  ? 611 LEU A CD2 1 
ATOM   3492  N N   . GLU A 1 613 ? 106.818 114.993 124.531 1.00 122.23 ? 612 GLU A N   1 
ATOM   3493  C CA  . GLU A 1 613 ? 107.141 116.080 125.447 1.00 122.65 ? 612 GLU A CA  1 
ATOM   3494  C C   . GLU A 1 613 ? 105.877 116.708 126.112 1.00 104.41 ? 612 GLU A C   1 
ATOM   3495  O O   . GLU A 1 613 ? 106.067 117.473 127.064 1.00 147.34 ? 612 GLU A O   1 
ATOM   3496  C CB  . GLU A 1 613 ? 108.060 117.048 124.697 1.00 180.69 ? 612 GLU A CB  1 
ATOM   3497  C CG  . GLU A 1 613 ? 108.684 118.146 125.556 1.00 260.35 ? 612 GLU A CG  1 
ATOM   3498  C CD  . GLU A 1 613 ? 109.453 119.200 124.776 1.00 375.00 ? 612 GLU A CD  1 
ATOM   3499  O OE1 . GLU A 1 613 ? 110.562 118.886 124.295 1.00 442.59 ? 612 GLU A OE1 1 
ATOM   3500  O OE2 . GLU A 1 613 ? 108.934 120.335 124.646 1.00 431.97 ? 612 GLU A OE2 1 
ATOM   3501  N N   . ARG A 1 614 ? 104.616 116.416 125.700 1.00 71.45  ? 613 ARG A N   1 
ATOM   3502  C CA  . ARG A 1 614 ? 103.393 117.019 126.262 1.00 110.70 ? 613 ARG A CA  1 
ATOM   3503  C C   . ARG A 1 614 ? 102.278 115.988 126.553 1.00 124.49 ? 613 ARG A C   1 
ATOM   3504  O O   . ARG A 1 614 ? 101.077 116.261 126.621 1.00 133.58 ? 613 ARG A O   1 
ATOM   3505  C CB  . ARG A 1 614 ? 102.884 118.106 125.302 1.00 185.84 ? 613 ARG A CB  1 
ATOM   3506  C CG  . ARG A 1 614 ? 103.435 119.487 125.628 1.00 229.31 ? 613 ARG A CG  1 
ATOM   3507  C CD  . ARG A 1 614 ? 103.297 120.554 124.553 1.00 231.03 ? 613 ARG A CD  1 
ATOM   3508  N NE  . ARG A 1 614 ? 104.201 120.341 123.417 1.00 299.10 ? 613 ARG A NE  1 
ATOM   3509  C CZ  . ARG A 1 614 ? 105.542 120.436 123.411 1.00 342.72 ? 613 ARG A CZ  1 
ATOM   3510  N NH1 . ARG A 1 614 ? 106.197 120.132 122.301 1.00 416.38 ? 613 ARG A NH1 1 
ATOM   3511  N NH2 . ARG A 1 614 ? 106.234 120.814 124.480 1.00 284.24 ? 613 ARG A NH2 1 
ATOM   3512  N N   . LEU A 1 615 ? 102.704 114.756 126.748 1.00 115.12 ? 614 LEU A N   1 
ATOM   3513  C CA  . LEU A 1 615 ? 101.890 113.627 127.148 1.00 119.40 ? 614 LEU A CA  1 
ATOM   3514  C C   . LEU A 1 615 ? 101.447 113.752 128.601 1.00 125.20 ? 614 LEU A C   1 
ATOM   3515  O O   . LEU A 1 615 ? 102.114 114.448 129.384 1.00 207.40 ? 614 LEU A O   1 
ATOM   3516  C CB  . LEU A 1 615 ? 102.855 112.447 126.988 1.00 106.18 ? 614 LEU A CB  1 
ATOM   3517  C CG  . LEU A 1 615 ? 102.295 111.080 127.237 1.00 114.83 ? 614 LEU A CG  1 
ATOM   3518  C CD1 . LEU A 1 615 ? 101.135 110.850 126.290 1.00 222.21 ? 614 LEU A CD1 1 
ATOM   3519  C CD2 . LEU A 1 615 ? 103.378 110.080 126.963 1.00 110.94 ? 614 LEU A CD2 1 
ATOM   3520  N N   . LYS A 1 616 ? 100.368 113.049 128.974 1.00 110.80 ? 615 LYS A N   1 
ATOM   3521  C CA  . LYS A 1 616 ? 99.901  113.065 130.351 1.00 138.48 ? 615 LYS A CA  1 
ATOM   3522  C C   . LYS A 1 616 ? 99.456  111.677 130.829 1.00 114.52 ? 615 LYS A C   1 
ATOM   3523  O O   . LYS A 1 616 ? 98.367  111.251 130.496 1.00 171.76 ? 615 LYS A O   1 
ATOM   3524  C CB  . LYS A 1 616 ? 98.746  114.077 130.482 1.00 162.82 ? 615 LYS A CB  1 
ATOM   3525  C CG  . LYS A 1 616 ? 99.008  115.537 130.078 1.00 151.61 ? 615 LYS A CG  1 
ATOM   3526  C CD  . LYS A 1 616 ? 98.305  116.584 130.968 1.00 214.16 ? 615 LYS A CD  1 
ATOM   3527  C CE  . LYS A 1 616 ? 96.809  116.374 131.138 1.00 302.11 ? 615 LYS A CE  1 
ATOM   3528  N NZ  . LYS A 1 616 ? 96.257  117.123 132.296 1.00 332.13 ? 615 LYS A NZ  1 
ATOM   3529  N N   . LEU A 1 617 ? 100.272 110.967 131.627 1.00 93.68  ? 616 LEU A N   1 
ATOM   3530  C CA  . LEU A 1 617 ? 99.895  109.703 132.271 1.00 83.49  ? 616 LEU A CA  1 
ATOM   3531  C C   . LEU A 1 617 ? 98.979  109.953 133.479 1.00 85.23  ? 616 LEU A C   1 
ATOM   3532  O O   . LEU A 1 617 ? 99.194  110.871 134.278 1.00 105.72 ? 616 LEU A O   1 
ATOM   3533  C CB  . LEU A 1 617 ? 101.149 109.006 132.802 1.00 81.32  ? 616 LEU A CB  1 
ATOM   3534  C CG  . LEU A 1 617 ? 102.267 108.513 131.859 1.00 100.13 ? 616 LEU A CG  1 
ATOM   3535  C CD1 . LEU A 1 617 ? 101.763 107.424 130.916 1.00 106.79 ? 616 LEU A CD1 1 
ATOM   3536  C CD2 . LEU A 1 617 ? 102.999 109.680 131.094 1.00 106.09 ? 616 LEU A CD2 1 
ATOM   3537  N N   . GLU A 1 618 ? 97.961  109.114 133.665 1.00 78.43  ? 617 GLU A N   1 
ATOM   3538  C CA  . GLU A 1 618 ? 97.209  109.093 134.928 1.00 90.92  ? 617 GLU A CA  1 
ATOM   3539  C C   . GLU A 1 618 ? 97.906  108.155 135.898 1.00 79.49  ? 617 GLU A C   1 
ATOM   3540  O O   . GLU A 1 618 ? 98.788  107.439 135.468 1.00 91.68  ? 617 GLU A O   1 
ATOM   3541  C CB  . GLU A 1 618 ? 95.748  108.693 134.762 1.00 116.52 ? 617 GLU A CB  1 
ATOM   3542  C CG  . GLU A 1 618 ? 94.958  109.738 133.989 1.00 236.77 ? 617 GLU A CG  1 
ATOM   3543  C CD  . GLU A 1 618 ? 94.924  111.153 134.585 1.00 294.14 ? 617 GLU A CD  1 
ATOM   3544  O OE1 . GLU A 1 618 ? 94.586  111.262 135.781 1.00 348.04 ? 617 GLU A OE1 1 
ATOM   3545  O OE2 . GLU A 1 618 ? 95.226  112.160 133.861 1.00 277.66 ? 617 GLU A OE2 1 
ATOM   3546  N N   . PRO A 1 619 ? 97.600  108.142 137.219 1.00 74.02  ? 618 PRO A N   1 
ATOM   3547  C CA  . PRO A 1 619 ? 98.159  107.159 138.144 1.00 66.65  ? 618 PRO A CA  1 
ATOM   3548  C C   . PRO A 1 619 ? 97.929  105.733 137.658 1.00 90.11  ? 618 PRO A C   1 
ATOM   3549  O O   . PRO A 1 619 ? 96.811  105.340 137.322 1.00 127.27 ? 618 PRO A O   1 
ATOM   3550  C CB  . PRO A 1 619 ? 97.370  107.366 139.410 1.00 97.30  ? 618 PRO A CB  1 
ATOM   3551  C CG  . PRO A 1 619 ? 97.005  108.813 139.374 1.00 114.50 ? 618 PRO A CG  1 
ATOM   3552  C CD  . PRO A 1 619 ? 96.743  109.103 137.915 1.00 108.77 ? 618 PRO A CD  1 
ATOM   3553  N N   . HIS A 1 620 ? 99.018  104.972 137.578 1.00 81.10  ? 619 HIS A N   1 
ATOM   3554  C CA  . HIS A 1 620 ? 99.018  103.606 137.095 1.00 80.80  ? 619 HIS A CA  1 
ATOM   3555  C C   . HIS A 1 620 ? 98.673  103.426 135.592 1.00 69.61  ? 619 HIS A C   1 
ATOM   3556  O O   . HIS A 1 620 ? 98.430  102.317 135.114 1.00 70.89  ? 619 HIS A O   1 
ATOM   3557  C CB  . HIS A 1 620 ? 98.131  102.877 138.104 1.00 89.64  ? 619 HIS A CB  1 
ATOM   3558  C CG  . HIS A 1 620 ? 98.522  102.990 139.544 1.00 85.94  ? 619 HIS A CG  1 
ATOM   3559  N ND1 . HIS A 1 620 ? 97.664  103.451 140.522 1.00 115.51 ? 619 HIS A ND1 1 
ATOM   3560  C CD2 . HIS A 1 620 ? 99.665  102.600 140.181 1.00 89.15  ? 619 HIS A CD2 1 
ATOM   3561  C CE1 . HIS A 1 620 ? 98.303  103.371 141.697 1.00 175.45 ? 619 HIS A CE1 1 
ATOM   3562  N NE2 . HIS A 1 620 ? 99.523  102.860 141.513 1.00 108.45 ? 619 HIS A NE2 1 
ATOM   3563  N N   . GLU A 1 621 ? 98.629  104.492 134.812 1.00 57.08  ? 620 GLU A N   1 
ATOM   3564  C CA  . GLU A 1 621 ? 98.381  104.325 133.395 1.00 78.67  ? 620 GLU A CA  1 
ATOM   3565  C C   . GLU A 1 621 ? 99.660  103.837 132.758 1.00 64.69  ? 620 GLU A C   1 
ATOM   3566  O O   . GLU A 1 621 ? 100.638 104.564 132.699 1.00 111.51 ? 620 GLU A O   1 
ATOM   3567  C CB  . GLU A 1 621 ? 97.969  105.649 132.712 1.00 108.82 ? 620 GLU A CB  1 
ATOM   3568  C CG  . GLU A 1 621 ? 97.960  105.676 131.170 1.00 110.59 ? 620 GLU A CG  1 
ATOM   3569  C CD  . GLU A 1 621 ? 96.948  106.646 130.560 1.00 172.26 ? 620 GLU A CD  1 
ATOM   3570  O OE1 . GLU A 1 621 ? 96.722  107.744 131.138 1.00 202.35 ? 620 GLU A OE1 1 
ATOM   3571  O OE2 . GLU A 1 621 ? 96.363  106.333 129.497 1.00 255.59 ? 620 GLU A OE2 1 
ATOM   3572  N N   . GLY A 1 622 ? 99.651  102.651 132.223 1.00 59.41  ? 621 GLY A N   1 
ATOM   3573  C CA  . GLY A 1 622 ? 100.693 102.341 131.245 1.00 76.51  ? 621 GLY A CA  1 
ATOM   3574  C C   . GLY A 1 622 ? 100.344 102.590 129.779 1.00 62.90  ? 621 GLY A C   1 
ATOM   3575  O O   . GLY A 1 622 ? 99.234  102.360 129.388 1.00 82.36  ? 621 GLY A O   1 
ATOM   3576  N N   . LEU A 1 623 ? 101.323 102.988 128.980 1.00 73.04  ? 622 LEU A N   1 
ATOM   3577  C CA  . LEU A 1 623 ? 101.181 103.144 127.549 1.00 77.81  ? 622 LEU A CA  1 
ATOM   3578  C C   . LEU A 1 623 ? 102.115 102.234 126.786 1.00 96.37  ? 622 LEU A C   1 
ATOM   3579  O O   . LEU A 1 623 ? 103.249 102.041 127.209 1.00 117.79 ? 622 LEU A O   1 
ATOM   3580  C CB  . LEU A 1 623 ? 101.672 104.535 127.209 1.00 81.71  ? 622 LEU A CB  1 
ATOM   3581  C CG  . LEU A 1 623 ? 100.877 105.632 127.868 1.00 90.62  ? 622 LEU A CG  1 
ATOM   3582  C CD1 . LEU A 1 623 ? 101.435 106.920 127.356 1.00 132.00 ? 622 LEU A CD1 1 
ATOM   3583  C CD2 . LEU A 1 623 ? 99.408  105.532 127.567 1.00 74.16  ? 622 LEU A CD2 1 
ATOM   3584  N N   . LEU A 1 624 ? 101.641 101.715 125.651 1.00 68.93  ? 623 LEU A N   1 
ATOM   3585  C CA  . LEU A 1 624 ? 102.516 101.093 124.670 1.00 68.51  ? 623 LEU A CA  1 
ATOM   3586  C C   . LEU A 1 624 ? 102.526 101.956 123.420 1.00 65.58  ? 623 LEU A C   1 
ATOM   3587  O O   . LEU A 1 624 ? 101.560 102.013 122.725 1.00 98.47  ? 623 LEU A O   1 
ATOM   3588  C CB  . LEU A 1 624 ? 101.969 99.698  124.408 1.00 67.49  ? 623 LEU A CB  1 
ATOM   3589  C CG  . LEU A 1 624 ? 102.740 98.820  123.435 1.00 73.86  ? 623 LEU A CG  1 
ATOM   3590  C CD1 . LEU A 1 624 ? 104.203 98.840  123.721 1.00 61.87  ? 623 LEU A CD1 1 
ATOM   3591  C CD2 . LEU A 1 624 ? 102.223 97.355  123.509 1.00 96.81  ? 623 LEU A CD2 1 
ATOM   3592  N N   . LEU A 1 625 ? 103.620 102.638 123.140 1.00 105.85 ? 624 LEU A N   1 
ATOM   3593  C CA  . LEU A 1 625 ? 103.742 103.425 121.930 1.00 94.37  ? 624 LEU A CA  1 
ATOM   3594  C C   . LEU A 1 625 ? 104.607 102.585 120.990 1.00 115.93 ? 624 LEU A C   1 
ATOM   3595  O O   . LEU A 1 625 ? 105.535 101.868 121.379 1.00 103.90 ? 624 LEU A O   1 
ATOM   3596  C CB  . LEU A 1 625 ? 104.359 104.796 122.262 1.00 82.36  ? 624 LEU A CB  1 
ATOM   3597  C CG  . LEU A 1 625 ? 103.736 105.447 123.498 1.00 107.30 ? 624 LEU A CG  1 
ATOM   3598  C CD1 . LEU A 1 625 ? 104.257 106.834 123.753 1.00 144.65 ? 624 LEU A CD1 1 
ATOM   3599  C CD2 . LEU A 1 625 ? 102.235 105.518 123.352 1.00 88.86  ? 624 LEU A CD2 1 
ATOM   3600  N N   . ARG A 1 626 ? 104.275 102.750 119.726 1.00 117.28 ? 625 ARG A N   1 
ATOM   3601  C CA  . ARG A 1 626 ? 104.912 102.128 118.589 1.00 120.46 ? 625 ARG A CA  1 
ATOM   3602  C C   . ARG A 1 626 ? 105.509 103.290 117.768 1.00 101.40 ? 625 ARG A C   1 
ATOM   3603  O O   . ARG A 1 626 ? 104.869 104.330 117.584 1.00 115.93 ? 625 ARG A O   1 
ATOM   3604  C CB  . ARG A 1 626 ? 103.756 101.307 118.009 1.00 180.93 ? 625 ARG A CB  1 
ATOM   3605  C CG  . ARG A 1 626 ? 103.855 100.872 116.571 1.00 197.00 ? 625 ARG A CG  1 
ATOM   3606  C CD  . ARG A 1 626 ? 102.555 100.289 116.005 1.00 165.80 ? 625 ARG A CD  1 
ATOM   3607  N NE  . ARG A 1 626 ? 103.003 99.581  114.805 1.00 205.18 ? 625 ARG A NE  1 
ATOM   3608  C CZ  . ARG A 1 626 ? 103.109 98.256  114.669 1.00 243.64 ? 625 ARG A CZ  1 
ATOM   3609  N NH1 . ARG A 1 626 ? 103.855 97.745  113.699 1.00 330.55 ? 625 ARG A NH1 1 
ATOM   3610  N NH2 . ARG A 1 626 ? 102.504 97.432  115.513 1.00 183.64 ? 625 ARG A NH2 1 
ATOM   3611  N N   . PHE A 1 627 ? 106.728 103.156 117.255 1.00 104.71 ? 626 PHE A N   1 
ATOM   3612  C CA  . PHE A 1 627 ? 107.278 104.219 116.420 1.00 144.00 ? 626 PHE A CA  1 
ATOM   3613  C C   . PHE A 1 627 ? 108.275 103.679 115.399 1.00 172.81 ? 626 PHE A C   1 
ATOM   3614  O O   . PHE A 1 627 ? 108.951 102.690 115.666 1.00 181.15 ? 626 PHE A O   1 
ATOM   3615  C CB  . PHE A 1 627 ? 107.915 105.334 117.253 1.00 127.17 ? 626 PHE A CB  1 
ATOM   3616  C CG  . PHE A 1 627 ? 109.091 105.019 118.138 1.00 107.45 ? 626 PHE A CG  1 
ATOM   3617  C CD1 . PHE A 1 627 ? 110.385 104.820 117.652 1.00 146.80 ? 626 PHE A CD1 1 
ATOM   3618  C CD2 . PHE A 1 627 ? 108.905 104.958 119.492 1.00 134.21 ? 626 PHE A CD2 1 
ATOM   3619  C CE1 . PHE A 1 627 ? 111.452 104.540 118.487 1.00 130.56 ? 626 PHE A CE1 1 
ATOM   3620  C CE2 . PHE A 1 627 ? 109.981 104.670 120.326 1.00 120.61 ? 626 PHE A CE2 1 
ATOM   3621  C CZ  . PHE A 1 627 ? 111.236 104.461 119.829 1.00 113.27 ? 626 PHE A CZ  1 
ATOM   3622  N N   . PRO A 1 628 ? 108.400 104.305 114.202 1.00 149.40 ? 627 PRO A N   1 
ATOM   3623  C CA  . PRO A 1 628 ? 109.250 103.743 113.162 1.00 128.64 ? 627 PRO A CA  1 
ATOM   3624  C C   . PRO A 1 628 ? 110.723 104.088 113.291 1.00 111.15 ? 627 PRO A C   1 
ATOM   3625  O O   . PRO A 1 628 ? 111.082 105.029 113.994 1.00 146.73 ? 627 PRO A O   1 
ATOM   3626  C CB  . PRO A 1 628 ? 108.662 104.442 111.933 1.00 228.74 ? 627 PRO A CB  1 
ATOM   3627  C CG  . PRO A 1 628 ? 108.328 105.837 112.446 1.00 217.69 ? 627 PRO A CG  1 
ATOM   3628  C CD  . PRO A 1 628 ? 107.742 105.566 113.807 1.00 174.91 ? 627 PRO A CD  1 
ATOM   3629  N N   . TYR A 1 629 ? 111.549 103.321 112.561 1.00 142.44 ? 628 TYR A N   1 
ATOM   3630  C CA  . TYR A 1 629 ? 113.003 103.471 112.486 1.00 147.83 ? 628 TYR A CA  1 
ATOM   3631  C C   . TYR A 1 629 ? 113.464 104.829 111.917 1.00 156.79 ? 628 TYR A C   1 
ATOM   3632  O O   . TYR A 1 629 ? 112.680 105.590 111.319 1.00 120.70 ? 628 TYR A O   1 
ATOM   3633  C CB  . TYR A 1 629 ? 113.522 102.313 111.622 1.00 162.26 ? 628 TYR A CB  1 
ATOM   3634  C CG  . TYR A 1 629 ? 115.037 102.169 111.613 1.00 150.75 ? 628 TYR A CG  1 
ATOM   3635  C CD1 . TYR A 1 629 ? 115.729 101.919 112.795 1.00 214.23 ? 628 TYR A CD1 1 
ATOM   3636  C CD2 . TYR A 1 629 ? 115.784 102.287 110.446 1.00 167.59 ? 628 TYR A CD2 1 
ATOM   3637  C CE1 . TYR A 1 629 ? 117.111 101.781 112.816 1.00 254.12 ? 628 TYR A CE1 1 
ATOM   3638  C CE2 . TYR A 1 629 ? 117.169 102.153 110.451 1.00 186.13 ? 628 TYR A CE2 1 
ATOM   3639  C CZ  . TYR A 1 629 ? 117.838 101.901 111.643 1.00 209.22 ? 628 TYR A CZ  1 
ATOM   3640  O OH  . TYR A 1 629 ? 119.198 101.757 111.708 1.00 197.68 ? 628 TYR A OH  1 
ATOM   3641  N N   . ALA A 1 630 ? 114.759 105.116 112.151 1.00 149.55 ? 629 ALA A N   1 
ATOM   3642  C CA  . ALA A 1 630 ? 115.523 106.153 111.469 1.00 188.30 ? 629 ALA A CA  1 
ATOM   3643  C C   . ALA A 1 630 ? 116.976 105.682 111.318 1.00 215.79 ? 629 ALA A C   1 
ATOM   3644  O O   . ALA A 1 630 ? 117.595 105.172 112.262 1.00 153.22 ? 629 ALA A O   1 
ATOM   3645  C CB  . ALA A 1 630 ? 115.451 107.468 112.210 1.00 205.27 ? 629 ALA A CB  1 
ATOM   3646  N N   . ALA A 1 631 ? 117.519 105.866 110.103 1.00 314.90 ? 630 ALA A N   1 
ATOM   3647  C CA  . ALA A 1 631 ? 118.885 105.485 109.768 1.00 414.95 ? 630 ALA A CA  1 
ATOM   3648  C C   . ALA A 1 631 ? 119.874 106.500 110.367 1.00 434.84 ? 630 ALA A C   1 
ATOM   3649  O O   . ALA A 1 631 ? 120.282 107.441 109.646 1.00 465.53 ? 630 ALA A O   1 
ATOM   3650  C CB  . ALA A 1 631 ? 119.025 105.359 108.265 1.00 473.14 ? 630 ALA A CB  1 
ATOM   3651  N N   . VAL B 2 44  ? 108.812 101.982 54.710  1.00 295.05 ? 44  VAL B N   1 
ATOM   3652  C CA  . VAL B 2 44  ? 109.291 102.482 56.041  1.00 305.58 ? 44  VAL B CA  1 
ATOM   3653  C C   . VAL B 2 44  ? 108.408 101.985 57.189  1.00 346.15 ? 44  VAL B C   1 
ATOM   3654  O O   . VAL B 2 44  ? 108.919 101.843 58.302  1.00 388.13 ? 44  VAL B O   1 
ATOM   3655  C CB  . VAL B 2 44  ? 109.410 104.022 56.101  1.00 316.60 ? 44  VAL B CB  1 
ATOM   3656  C CG1 . VAL B 2 44  ? 110.257 104.561 54.957  1.00 408.12 ? 44  VAL B CG1 1 
ATOM   3657  C CG2 . VAL B 2 44  ? 108.071 104.750 56.147  1.00 258.94 ? 44  VAL B CG2 1 
ATOM   3658  N N   . THR B 2 45  ? 107.110 101.733 56.940  1.00 369.49 ? 45  THR B N   1 
ATOM   3659  C CA  . THR B 2 45  ? 106.159 101.365 57.987  1.00 366.41 ? 45  THR B CA  1 
ATOM   3660  C C   . THR B 2 45  ? 106.515 100.006 58.620  1.00 353.15 ? 45  THR B C   1 
ATOM   3661  O O   . THR B 2 45  ? 107.116 99.149  57.964  1.00 296.15 ? 45  THR B O   1 
ATOM   3662  C CB  . THR B 2 45  ? 104.726 101.413 57.427  1.00 347.76 ? 45  THR B CB  1 
ATOM   3663  O OG1 . THR B 2 45  ? 104.516 102.721 56.886  1.00 381.92 ? 45  THR B OG1 1 
ATOM   3664  C CG2 . THR B 2 45  ? 103.657 101.096 58.455  1.00 266.97 ? 45  THR B CG2 1 
ATOM   3665  N N   . LEU B 2 46  ? 106.126 99.845  59.909  1.00 317.11 ? 46  LEU B N   1 
ATOM   3666  C CA  . LEU B 2 46  ? 106.457 98.724  60.793  1.00 249.89 ? 46  LEU B CA  1 
ATOM   3667  C C   . LEU B 2 46  ? 106.180 97.370  60.144  1.00 254.77 ? 46  LEU B C   1 
ATOM   3668  O O   . LEU B 2 46  ? 105.061 97.139  59.679  1.00 260.45 ? 46  LEU B O   1 
ATOM   3669  C CB  . LEU B 2 46  ? 105.605 98.828  62.066  1.00 243.28 ? 46  LEU B CB  1 
ATOM   3670  C CG  . LEU B 2 46  ? 106.126 99.687  63.221  1.00 258.24 ? 46  LEU B CG  1 
ATOM   3671  C CD1 . LEU B 2 46  ? 106.572 101.073 62.795  1.00 289.02 ? 46  LEU B CD1 1 
ATOM   3672  C CD2 . LEU B 2 46  ? 105.043 99.829  64.275  1.00 257.13 ? 46  LEU B CD2 1 
ATOM   3673  N N   . GLN B 2 47  ? 107.190 96.484  60.137  1.00 260.89 ? 47  GLN B N   1 
ATOM   3674  C CA  . GLN B 2 47  ? 107.018 95.126  59.632  1.00 296.80 ? 47  GLN B CA  1 
ATOM   3675  C C   . GLN B 2 47  ? 106.181 94.287  60.597  1.00 274.47 ? 47  GLN B C   1 
ATOM   3676  O O   . GLN B 2 47  ? 106.370 94.388  61.807  1.00 271.36 ? 47  GLN B O   1 
ATOM   3677  C CB  . GLN B 2 47  ? 108.360 94.427  59.400  1.00 310.79 ? 47  GLN B CB  1 
ATOM   3678  C CG  . GLN B 2 47  ? 108.941 94.710  58.022  1.00 394.33 ? 47  GLN B CG  1 
ATOM   3679  C CD  . GLN B 2 47  ? 110.138 93.853  57.679  1.00 455.17 ? 47  GLN B CD  1 
ATOM   3680  O OE1 . GLN B 2 47  ? 110.631 93.072  58.493  1.00 454.77 ? 47  GLN B OE1 1 
ATOM   3681  N NE2 . GLN B 2 47  ? 110.620 93.991  56.452  1.00 485.57 ? 47  GLN B NE2 1 
ATOM   3682  N N   . ARG B 2 48  ? 105.266 93.467  60.037  1.00 262.56 ? 48  ARG B N   1 
ATOM   3683  C CA  . ARG B 2 48  ? 104.570 92.425  60.778  1.00 256.00 ? 48  ARG B CA  1 
ATOM   3684  C C   . ARG B 2 48  ? 105.550 91.299  61.083  1.00 256.41 ? 48  ARG B C   1 
ATOM   3685  O O   . ARG B 2 48  ? 106.125 90.747  60.146  1.00 323.47 ? 48  ARG B O   1 
ATOM   3686  C CB  . ARG B 2 48  ? 103.388 91.852  59.983  1.00 227.49 ? 48  ARG B CB  1 
ATOM   3687  C CG  . ARG B 2 48  ? 102.236 92.830  59.795  1.00 249.14 ? 48  ARG B CG  1 
ATOM   3688  C CD  . ARG B 2 48  ? 101.131 92.265  58.925  1.00 244.20 ? 48  ARG B CD  1 
ATOM   3689  N NE  . ARG B 2 48  ? 100.016 93.197  58.792  1.00 241.98 ? 48  ARG B NE  1 
ATOM   3690  C CZ  . ARG B 2 48  ? 99.009  93.355  59.656  1.00 271.09 ? 48  ARG B CZ  1 
ATOM   3691  N NH1 . ARG B 2 48  ? 98.090  94.278  59.423  1.00 351.14 ? 48  ARG B NH1 1 
ATOM   3692  N NH2 . ARG B 2 48  ? 98.897  92.610  60.747  1.00 238.13 ? 48  ARG B NH2 1 
ATOM   3693  N N   . ASN B 2 49  ? 105.744 90.967  62.374  1.00 244.50 ? 49  ASN B N   1 
ATOM   3694  C CA  . ASN B 2 49  ? 106.571 89.813  62.739  1.00 301.56 ? 49  ASN B CA  1 
ATOM   3695  C C   . ASN B 2 49  ? 106.184 89.141  64.066  1.00 255.97 ? 49  ASN B C   1 
ATOM   3696  O O   . ASN B 2 49  ? 106.891 88.228  64.514  1.00 229.31 ? 49  ASN B O   1 
ATOM   3697  C CB  . ASN B 2 49  ? 108.065 90.177  62.718  1.00 320.95 ? 49  ASN B CB  1 
ATOM   3698  C CG  . ASN B 2 49  ? 108.453 91.312  63.640  1.00 302.98 ? 49  ASN B CG  1 
ATOM   3699  O OD1 . ASN B 2 49  ? 108.020 91.359  64.787  1.00 296.69 ? 49  ASN B OD1 1 
ATOM   3700  N ND2 . ASN B 2 49  ? 109.268 92.235  63.150  1.00 329.73 ? 49  ASN B ND2 1 
ATOM   3701  N N   . ILE B 2 50  ? 105.075 89.551  64.699  1.00 225.45 ? 50  ILE B N   1 
ATOM   3702  C CA  . ILE B 2 50  ? 104.586 88.868  65.891  1.00 248.98 ? 50  ILE B CA  1 
ATOM   3703  C C   . ILE B 2 50  ? 103.846 87.602  65.450  1.00 229.84 ? 50  ILE B C   1 
ATOM   3704  O O   . ILE B 2 50  ? 102.802 87.681  64.801  1.00 212.05 ? 50  ILE B O   1 
ATOM   3705  C CB  . ILE B 2 50  ? 103.714 89.796  66.769  1.00 238.66 ? 50  ILE B CB  1 
ATOM   3706  C CG1 . ILE B 2 50  ? 104.459 91.067  67.184  1.00 253.37 ? 50  ILE B CG1 1 
ATOM   3707  C CG2 . ILE B 2 50  ? 103.197 89.074  67.998  1.00 240.94 ? 50  ILE B CG2 1 
ATOM   3708  C CD1 . ILE B 2 50  ? 103.595 92.110  67.846  1.00 211.12 ? 50  ILE B CD1 1 
ATOM   3709  N N   . THR B 2 51  ? 104.400 86.434  65.822  1.00 211.28 ? 51  THR B N   1 
ATOM   3710  C CA  . THR B 2 51  ? 103.793 85.139  65.542  1.00 244.67 ? 51  THR B CA  1 
ATOM   3711  C C   . THR B 2 51  ? 102.663 84.864  66.536  1.00 207.57 ? 51  THR B C   1 
ATOM   3712  O O   . THR B 2 51  ? 102.435 85.654  67.438  1.00 251.64 ? 51  THR B O   1 
ATOM   3713  C CB  . THR B 2 51  ? 104.861 84.034  65.564  1.00 285.42 ? 51  THR B CB  1 
ATOM   3714  O OG1 . THR B 2 51  ? 105.400 83.926  66.874  1.00 243.17 ? 51  THR B OG1 1 
ATOM   3715  C CG2 . THR B 2 51  ? 106.016 84.282  64.617  1.00 331.10 ? 51  THR B CG2 1 
ATOM   3716  N N   . LEU B 2 52  ? 101.964 83.730  66.403  1.00 239.57 ? 52  LEU B N   1 
ATOM   3717  C CA  . LEU B 2 52  ? 101.082 83.269  67.470  1.00 274.26 ? 52  LEU B CA  1 
ATOM   3718  C C   . LEU B 2 52  ? 101.848 83.142  68.794  1.00 279.33 ? 52  LEU B C   1 
ATOM   3719  O O   . LEU B 2 52  ? 101.376 83.639  69.821  1.00 247.52 ? 52  LEU B O   1 
ATOM   3720  C CB  . LEU B 2 52  ? 100.453 81.915  67.117  1.00 317.53 ? 52  LEU B CB  1 
ATOM   3721  C CG  . LEU B 2 52  ? 99.624  81.278  68.236  1.00 296.47 ? 52  LEU B CG  1 
ATOM   3722  C CD1 . LEU B 2 52  ? 98.418  82.148  68.554  1.00 223.84 ? 52  LEU B CD1 1 
ATOM   3723  C CD2 . LEU B 2 52  ? 99.205  79.860  67.875  1.00 328.03 ? 52  LEU B CD2 1 
ATOM   3724  N N   . LEU B 2 53  ? 103.013 82.471  68.766  1.00 254.59 ? 53  LEU B N   1 
ATOM   3725  C CA  . LEU B 2 53  ? 103.750 82.162  69.984  1.00 232.07 ? 53  LEU B CA  1 
ATOM   3726  C C   . LEU B 2 53  ? 104.223 83.449  70.660  1.00 188.87 ? 53  LEU B C   1 
ATOM   3727  O O   . LEU B 2 53  ? 104.117 83.544  71.880  1.00 190.75 ? 53  LEU B O   1 
ATOM   3728  C CB  . LEU B 2 53  ? 104.920 81.225  69.659  1.00 313.86 ? 53  LEU B CB  1 
ATOM   3729  C CG  . LEU B 2 53  ? 105.795 80.807  70.843  1.00 451.15 ? 53  LEU B CG  1 
ATOM   3730  C CD1 . LEU B 2 53  ? 105.002 79.991  71.855  1.00 507.88 ? 53  LEU B CD1 1 
ATOM   3731  C CD2 . LEU B 2 53  ? 107.007 80.029  70.357  1.00 501.70 ? 53  LEU B CD2 1 
ATOM   3732  N N   . ASN B 2 54  ? 104.720 84.429  69.880  1.00 210.81 ? 54  ASN B N   1 
ATOM   3733  C CA  . ASN B 2 54  ? 105.162 85.708  70.437  1.00 213.20 ? 54  ASN B CA  1 
ATOM   3734  C C   . ASN B 2 54  ? 103.971 86.553  70.907  1.00 169.74 ? 54  ASN B C   1 
ATOM   3735  O O   . ASN B 2 54  ? 104.132 87.357  71.815  1.00 197.19 ? 54  ASN B O   1 
ATOM   3736  C CB  . ASN B 2 54  ? 106.116 86.429  69.480  1.00 206.77 ? 54  ASN B CB  1 
ATOM   3737  C CG  . ASN B 2 54  ? 107.417 85.662  69.285  1.00 265.77 ? 54  ASN B CG  1 
ATOM   3738  O OD1 . ASN B 2 54  ? 107.722 84.690  69.994  1.00 164.23 ? 54  ASN B OD1 1 
ATOM   3739  N ND2 . ASN B 2 54  ? 108.200 86.094  68.309  1.00 323.32 ? 54  ASN B ND2 1 
ATOM   3740  N N   . GLY B 2 55  ? 102.779 86.369  70.338  1.00 174.40 ? 55  GLY B N   1 
ATOM   3741  C CA  . GLY B 2 55  ? 101.566 86.999  70.846  1.00 161.32 ? 55  GLY B CA  1 
ATOM   3742  C C   . GLY B 2 55  ? 101.117 86.394  72.163  1.00 153.50 ? 55  GLY B C   1 
ATOM   3743  O O   . GLY B 2 55  ? 100.769 87.148  73.064  1.00 156.07 ? 55  GLY B O   1 
ATOM   3744  N N   . VAL B 2 56  ? 101.145 85.057  72.274  1.00 160.41 ? 56  VAL B N   1 
ATOM   3745  C CA  . VAL B 2 56  ? 100.872 84.422  73.562  1.00 189.18 ? 56  VAL B CA  1 
ATOM   3746  C C   . VAL B 2 56  ? 101.912 84.857  74.599  1.00 190.34 ? 56  VAL B C   1 
ATOM   3747  O O   . VAL B 2 56  ? 101.553 85.146  75.732  1.00 158.66 ? 56  VAL B O   1 
ATOM   3748  C CB  . VAL B 2 56  ? 100.815 82.897  73.449  1.00 216.47 ? 56  VAL B CB  1 
ATOM   3749  C CG1 . VAL B 2 56  ? 100.781 82.221  74.811  1.00 223.76 ? 56  VAL B CG1 1 
ATOM   3750  C CG2 . VAL B 2 56  ? 99.619  82.471  72.633  1.00 250.44 ? 56  VAL B CG2 1 
ATOM   3751  N N   . ALA B 2 57  ? 103.191 84.924  74.215  1.00 193.71 ? 57  ALA B N   1 
ATOM   3752  C CA  . ALA B 2 57  ? 104.226 85.465  75.094  1.00 175.74 ? 57  ALA B CA  1 
ATOM   3753  C C   . ALA B 2 57  ? 103.952 86.923  75.490  1.00 129.77 ? 57  ALA B C   1 
ATOM   3754  O O   . ALA B 2 57  ? 104.247 87.279  76.613  1.00 177.47 ? 57  ALA B O   1 
ATOM   3755  C CB  . ALA B 2 57  ? 105.600 85.313  74.478  1.00 160.07 ? 57  ALA B CB  1 
ATOM   3756  N N   . ILE B 2 58  ? 103.384 87.760  74.618  1.00 146.52 ? 58  ILE B N   1 
ATOM   3757  C CA  . ILE B 2 58  ? 103.001 89.110  75.012  1.00 150.71 ? 58  ILE B CA  1 
ATOM   3758  C C   . ILE B 2 58  ? 101.912 89.021  76.068  1.00 143.75 ? 58  ILE B C   1 
ATOM   3759  O O   . ILE B 2 58  ? 102.066 89.717  77.062  1.00 172.97 ? 58  ILE B O   1 
ATOM   3760  C CB  . ILE B 2 58  ? 102.605 90.012  73.822  1.00 186.37 ? 58  ILE B CB  1 
ATOM   3761  C CG1 . ILE B 2 58  ? 103.871 90.484  73.094  1.00 191.60 ? 58  ILE B CG1 1 
ATOM   3762  C CG2 . ILE B 2 58  ? 101.731 91.190  74.261  1.00 182.87 ? 58  ILE B CG2 1 
ATOM   3763  C CD1 . ILE B 2 58  ? 103.662 91.027  71.723  1.00 212.22 ? 58  ILE B CD1 1 
ATOM   3764  N N   . ILE B 2 59  ? 100.856 88.205  75.882  1.00 126.82 ? 59  ILE B N   1 
ATOM   3765  C CA  . ILE B 2 59  ? 99.762  88.250  76.849  1.00 184.75 ? 59  ILE B CA  1 
ATOM   3766  C C   . ILE B 2 59  ? 100.173 87.537  78.149  1.00 172.25 ? 59  ILE B C   1 
ATOM   3767  O O   . ILE B 2 59  ? 100.116 88.142  79.206  1.00 168.32 ? 59  ILE B O   1 
ATOM   3768  C CB  . ILE B 2 59  ? 98.410  87.762  76.291  1.00 175.37 ? 59  ILE B CB  1 
ATOM   3769  C CG1 . ILE B 2 59  ? 98.021  88.497  75.007  1.00 211.99 ? 59  ILE B CG1 1 
ATOM   3770  C CG2 . ILE B 2 59  ? 97.314  87.898  77.352  1.00 147.83 ? 59  ILE B CG2 1 
ATOM   3771  C CD1 . ILE B 2 59  ? 96.709  88.021  74.409  1.00 279.57 ? 59  ILE B CD1 1 
ATOM   3772  N N   . VAL B 2 60  ? 100.595 86.279  78.109  1.00 151.75 ? 60  VAL B N   1 
ATOM   3773  C CA  . VAL B 2 60  ? 100.952 85.585  79.340  1.00 164.60 ? 60  VAL B CA  1 
ATOM   3774  C C   . VAL B 2 60  ? 102.155 86.288  79.975  1.00 188.93 ? 60  VAL B C   1 
ATOM   3775  O O   . VAL B 2 60  ? 102.185 86.427  81.185  1.00 260.41 ? 60  VAL B O   1 
ATOM   3776  C CB  . VAL B 2 60  ? 101.238 84.088  79.108  1.00 203.10 ? 60  VAL B CB  1 
ATOM   3777  C CG1 . VAL B 2 60  ? 101.691 83.349  80.363  1.00 215.75 ? 60  VAL B CG1 1 
ATOM   3778  C CG2 . VAL B 2 60  ? 100.022 83.393  78.521  1.00 258.13 ? 60  VAL B CG2 1 
ATOM   3779  N N   . GLY B 2 61  ? 103.140 86.733  79.187  1.00 183.70 ? 61  GLY B N   1 
ATOM   3780  C CA  . GLY B 2 61  ? 104.242 87.537  79.699  1.00 177.22 ? 61  GLY B CA  1 
ATOM   3781  C C   . GLY B 2 61  ? 103.802 88.828  80.391  1.00 155.18 ? 61  GLY B C   1 
ATOM   3782  O O   . GLY B 2 61  ? 104.251 89.083  81.495  1.00 163.35 ? 61  GLY B O   1 
ATOM   3783  N N   . THR B 2 62  ? 102.922 89.625  79.768  1.00 140.02 ? 62  THR B N   1 
ATOM   3784  C CA  . THR B 2 62  ? 102.547 90.934  80.303  1.00 170.61 ? 62  THR B CA  1 
ATOM   3785  C C   . THR B 2 62  ? 101.496 90.835  81.418  1.00 163.71 ? 62  THR B C   1 
ATOM   3786  O O   . THR B 2 62  ? 101.458 91.721  82.264  1.00 153.16 ? 62  THR B O   1 
ATOM   3787  C CB  . THR B 2 62  ? 102.072 91.926  79.220  1.00 173.65 ? 62  THR B CB  1 
ATOM   3788  O OG1 . THR B 2 62  ? 102.164 93.268  79.702  1.00 133.69 ? 62  THR B OG1 1 
ATOM   3789  C CG2 . THR B 2 62  ? 100.640 91.735  78.778  1.00 215.33 ? 62  THR B CG2 1 
ATOM   3790  N N   . ILE B 2 63  ? 100.636 89.804  81.429  1.00 171.42 ? 63  ILE B N   1 
ATOM   3791  C CA  . ILE B 2 63  ? 99.652  89.653  82.497  1.00 167.53 ? 63  ILE B CA  1 
ATOM   3792  C C   . ILE B 2 63  ? 100.312 89.081  83.743  1.00 164.85 ? 63  ILE B C   1 
ATOM   3793  O O   . ILE B 2 63  ? 100.200 89.691  84.806  1.00 187.18 ? 63  ILE B O   1 
ATOM   3794  C CB  . ILE B 2 63  ? 98.441  88.808  82.080  1.00 164.64 ? 63  ILE B CB  1 
ATOM   3795  C CG1 . ILE B 2 63  ? 97.640  89.494  80.980  1.00 209.90 ? 63  ILE B CG1 1 
ATOM   3796  C CG2 . ILE B 2 63  ? 97.568  88.544  83.275  1.00 147.00 ? 63  ILE B CG2 1 
ATOM   3797  C CD1 . ILE B 2 63  ? 96.429  88.736  80.503  1.00 226.32 ? 63  ILE B CD1 1 
ATOM   3798  N N   . ILE B 2 64  ? 100.978 87.929  83.607  1.00 139.25 ? 64  ILE B N   1 
ATOM   3799  C CA  . ILE B 2 64  ? 101.388 87.153  84.767  1.00 147.37 ? 64  ILE B CA  1 
ATOM   3800  C C   . ILE B 2 64  ? 102.210 88.027  85.709  1.00 182.77 ? 64  ILE B C   1 
ATOM   3801  O O   . ILE B 2 64  ? 101.963 87.969  86.911  1.00 256.38 ? 64  ILE B O   1 
ATOM   3802  C CB  . ILE B 2 64  ? 102.147 85.885  84.348  1.00 174.42 ? 64  ILE B CB  1 
ATOM   3803  C CG1 . ILE B 2 64  ? 101.187 84.876  83.712  1.00 246.89 ? 64  ILE B CG1 1 
ATOM   3804  C CG2 . ILE B 2 64  ? 102.937 85.236  85.467  1.00 143.99 ? 64  ILE B CG2 1 
ATOM   3805  C CD1 . ILE B 2 64  ? 100.226 84.194  84.654  1.00 190.24 ? 64  ILE B CD1 1 
ATOM   3806  N N   . GLY B 2 65  ? 103.165 88.800  85.178  1.00 134.88 ? 65  GLY B N   1 
ATOM   3807  C CA  . GLY B 2 65  ? 103.626 90.039  85.793  1.00 168.74 ? 65  GLY B CA  1 
ATOM   3808  C C   . GLY B 2 65  ? 103.990 89.980  87.288  1.00 183.12 ? 65  GLY B C   1 
ATOM   3809  O O   . GLY B 2 65  ? 104.700 89.073  87.726  1.00 160.21 ? 65  GLY B O   1 
ATOM   3810  N N   . SER B 2 66  ? 103.518 90.976  88.062  1.00 185.72 ? 66  SER B N   1 
ATOM   3811  C CA  . SER B 2 66  ? 103.780 91.108  89.489  1.00 186.57 ? 66  SER B CA  1 
ATOM   3812  C C   . SER B 2 66  ? 102.608 90.660  90.355  1.00 197.69 ? 66  SER B C   1 
ATOM   3813  O O   . SER B 2 66  ? 102.847 90.253  91.486  1.00 187.37 ? 66  SER B O   1 
ATOM   3814  C CB  . SER B 2 66  ? 104.106 92.544  89.833  1.00 194.31 ? 66  SER B CB  1 
ATOM   3815  O OG  . SER B 2 66  ? 102.972 93.385  89.746  1.00 133.05 ? 66  SER B OG  1 
ATOM   3816  N N   . GLY B 2 67  ? 101.371 90.775  89.840  1.00 205.48 ? 67  GLY B N   1 
ATOM   3817  C CA  . GLY B 2 67  ? 100.154 90.690  90.637  1.00 203.49 ? 67  GLY B CA  1 
ATOM   3818  C C   . GLY B 2 67  ? 100.063 89.431  91.507  1.00 180.49 ? 67  GLY B C   1 
ATOM   3819  O O   . GLY B 2 67  ? 99.614  89.485  92.646  1.00 152.13 ? 67  GLY B O   1 
ATOM   3820  N N   . ILE B 2 68  ? 100.515 88.297  90.968  1.00 170.17 ? 68  ILE B N   1 
ATOM   3821  C CA  . ILE B 2 68  ? 100.459 87.020  91.667  1.00 168.61 ? 68  ILE B CA  1 
ATOM   3822  C C   . ILE B 2 68  ? 101.543 86.861  92.744  1.00 166.64 ? 68  ILE B C   1 
ATOM   3823  O O   . ILE B 2 68  ? 101.540 85.884  93.499  1.00 199.35 ? 68  ILE B O   1 
ATOM   3824  C CB  . ILE B 2 68  ? 100.503 85.893  90.620  1.00 173.73 ? 68  ILE B CB  1 
ATOM   3825  C CG1 . ILE B 2 68  ? 100.015 84.555  91.181  1.00 199.01 ? 68  ILE B CG1 1 
ATOM   3826  C CG2 . ILE B 2 68  ? 101.878 85.766  89.998  1.00 148.56 ? 68  ILE B CG2 1 
ATOM   3827  C CD1 . ILE B 2 68  ? 98.647  84.622  91.848  1.00 204.45 ? 68  ILE B CD1 1 
ATOM   3828  N N   . PHE B 2 69  ? 102.462 87.818  92.842  1.00 148.70 ? 69  PHE B N   1 
ATOM   3829  C CA  . PHE B 2 69  ? 103.462 87.822  93.888  1.00 159.07 ? 69  PHE B CA  1 
ATOM   3830  C C   . PHE B 2 69  ? 103.233 88.965  94.885  1.00 180.87 ? 69  PHE B C   1 
ATOM   3831  O O   . PHE B 2 69  ? 103.433 88.757  96.078  1.00 190.18 ? 69  PHE B O   1 
ATOM   3832  C CB  . PHE B 2 69  ? 104.811 87.911  93.186  1.00 181.47 ? 69  PHE B CB  1 
ATOM   3833  C CG  . PHE B 2 69  ? 105.034 86.842  92.146  1.00 194.50 ? 69  PHE B CG  1 
ATOM   3834  C CD1 . PHE B 2 69  ? 105.139 85.498  92.498  1.00 214.57 ? 69  PHE B CD1 1 
ATOM   3835  C CD2 . PHE B 2 69  ? 105.153 87.179  90.813  1.00 208.16 ? 69  PHE B CD2 1 
ATOM   3836  C CE1 . PHE B 2 69  ? 105.360 84.512  91.543  1.00 217.02 ? 69  PHE B CE1 1 
ATOM   3837  C CE2 . PHE B 2 69  ? 105.373 86.191  89.863  1.00 254.70 ? 69  PHE B CE2 1 
ATOM   3838  C CZ  . PHE B 2 69  ? 105.478 84.859  90.224  1.00 231.10 ? 69  PHE B CZ  1 
ATOM   3839  N N   . VAL B 2 70  ? 102.826 90.157  94.408  1.00 163.42 ? 70  VAL B N   1 
ATOM   3840  C CA  . VAL B 2 70  ? 102.728 91.361  95.227  1.00 173.84 ? 70  VAL B CA  1 
ATOM   3841  C C   . VAL B 2 70  ? 101.319 91.574  95.815  1.00 182.81 ? 70  VAL B C   1 
ATOM   3842  O O   . VAL B 2 70  ? 101.178 92.343  96.766  1.00 222.09 ? 70  VAL B O   1 
ATOM   3843  C CB  . VAL B 2 70  ? 103.221 92.582  94.412  1.00 199.84 ? 70  VAL B CB  1 
ATOM   3844  C CG1 . VAL B 2 70  ? 102.207 93.097  93.399  1.00 223.09 ? 70  VAL B CG1 1 
ATOM   3845  C CG2 . VAL B 2 70  ? 103.675 93.740  95.294  1.00 277.85 ? 70  VAL B CG2 1 
ATOM   3846  N N   . THR B 2 71  ? 100.276 90.929  95.265  1.00 178.59 ? 71  THR B N   1 
ATOM   3847  C CA  . THR B 2 71  ? 98.882  91.204  95.628  1.00 189.89 ? 71  THR B CA  1 
ATOM   3848  C C   . THR B 2 71  ? 98.106  90.007  96.225  1.00 189.12 ? 71  THR B C   1 
ATOM   3849  O O   . THR B 2 71  ? 96.962  90.235  96.622  1.00 169.90 ? 71  THR B O   1 
ATOM   3850  C CB  . THR B 2 71  ? 98.199  91.827  94.387  1.00 241.96 ? 71  THR B CB  1 
ATOM   3851  O OG1 . THR B 2 71  ? 98.798  93.104  94.171  1.00 265.55 ? 71  THR B OG1 1 
ATOM   3852  C CG2 . THR B 2 71  ? 96.709  92.068  94.462  1.00 207.46 ? 71  THR B CG2 1 
ATOM   3853  N N   . PRO B 2 72  ? 98.575  88.730  96.357  1.00 190.71 ? 72  PRO B N   1 
ATOM   3854  C CA  . PRO B 2 72  ? 97.790  87.690  97.064  1.00 215.29 ? 72  PRO B CA  1 
ATOM   3855  C C   . PRO B 2 72  ? 97.242  88.032  98.461  1.00 213.64 ? 72  PRO B C   1 
ATOM   3856  O O   . PRO B 2 72  ? 96.159  87.592  98.826  1.00 188.85 ? 72  PRO B O   1 
ATOM   3857  C CB  . PRO B 2 72  ? 98.767  86.503  97.183  1.00 182.07 ? 72  PRO B CB  1 
ATOM   3858  C CG  . PRO B 2 72  ? 99.695  86.685  96.010  1.00 186.29 ? 72  PRO B CG  1 
ATOM   3859  C CD  . PRO B 2 72  ? 99.835  88.179  95.834  1.00 162.80 ? 72  PRO B CD  1 
ATOM   3860  N N   . THR B 2 73  ? 97.992  88.822  99.234  1.00 221.99 ? 73  THR B N   1 
ATOM   3861  C CA  . THR B 2 73  ? 97.537  89.420  100.484 1.00 226.31 ? 73  THR B CA  1 
ATOM   3862  C C   . THR B 2 73  ? 96.348  90.374  100.293 1.00 197.67 ? 73  THR B C   1 
ATOM   3863  O O   . THR B 2 73  ? 95.459  90.446  101.140 1.00 235.45 ? 73  THR B O   1 
ATOM   3864  C CB  . THR B 2 73  ? 98.674  90.238  101.117 1.00 281.96 ? 73  THR B CB  1 
ATOM   3865  O OG1 . THR B 2 73  ? 99.755  89.349  101.399 1.00 227.49 ? 73  THR B OG1 1 
ATOM   3866  C CG2 . THR B 2 73  ? 98.281  90.970  102.386 1.00 335.31 ? 73  THR B CG2 1 
ATOM   3867  N N   . GLY B 2 74  ? 96.358  91.128  99.188  1.00 205.14 ? 74  GLY B N   1 
ATOM   3868  C CA  . GLY B 2 74  ? 95.453  92.240  98.977  1.00 236.25 ? 74  GLY B CA  1 
ATOM   3869  C C   . GLY B 2 74  ? 94.004  91.789  98.859  1.00 241.54 ? 74  GLY B C   1 
ATOM   3870  O O   . GLY B 2 74  ? 93.136  92.455  99.412  1.00 242.38 ? 74  GLY B O   1 
ATOM   3871  N N   . VAL B 2 75  ? 93.753  90.664  98.172  1.00 221.35 ? 75  VAL B N   1 
ATOM   3872  C CA  . VAL B 2 75  ? 92.393  90.150  98.099  1.00 253.43 ? 75  VAL B CA  1 
ATOM   3873  C C   . VAL B 2 75  ? 92.001  89.601  99.474  1.00 308.45 ? 75  VAL B C   1 
ATOM   3874  O O   . VAL B 2 75  ? 90.880  89.830  99.904  1.00 406.95 ? 75  VAL B O   1 
ATOM   3875  C CB  . VAL B 2 75  ? 92.149  89.109  96.977  1.00 264.99 ? 75  VAL B CB  1 
ATOM   3876  C CG1 . VAL B 2 75  ? 92.606  89.621  95.615  1.00 248.83 ? 75  VAL B CG1 1 
ATOM   3877  C CG2 . VAL B 2 75  ? 92.737  87.728  97.257  1.00 248.09 ? 75  VAL B CG2 1 
ATOM   3878  N N   . LEU B 2 76  ? 92.904  88.885  100.160 1.00 291.07 ? 76  LEU B N   1 
ATOM   3879  C CA  . LEU B 2 76  ? 92.565  88.194  101.402 1.00 256.62 ? 76  LEU B CA  1 
ATOM   3880  C C   . LEU B 2 76  ? 92.239  89.180  102.542 1.00 201.27 ? 76  LEU B C   1 
ATOM   3881  O O   . LEU B 2 76  ? 91.394  88.897  103.375 1.00 129.51 ? 76  LEU B O   1 
ATOM   3882  C CB  . LEU B 2 76  ? 93.734  87.248  101.712 1.00 233.27 ? 76  LEU B CB  1 
ATOM   3883  C CG  . LEU B 2 76  ? 93.636  86.446  102.999 1.00 205.20 ? 76  LEU B CG  1 
ATOM   3884  C CD1 . LEU B 2 76  ? 92.507  85.447  102.905 1.00 194.10 ? 76  LEU B CD1 1 
ATOM   3885  C CD2 . LEU B 2 76  ? 94.974  85.791  103.318 1.00 172.92 ? 76  LEU B CD2 1 
ATOM   3886  N N   . LYS B 2 77  ? 92.887  90.345  102.579 1.00 209.84 ? 77  LYS B N   1 
ATOM   3887  C CA  . LYS B 2 77  ? 92.570  91.401  103.534 1.00 235.03 ? 77  LYS B CA  1 
ATOM   3888  C C   . LYS B 2 77  ? 91.146  91.958  103.367 1.00 227.76 ? 77  LYS B C   1 
ATOM   3889  O O   . LYS B 2 77  ? 90.582  92.450  104.346 1.00 218.11 ? 77  LYS B O   1 
ATOM   3890  C CB  . LYS B 2 77  ? 93.631  92.501  103.402 1.00 334.47 ? 77  LYS B CB  1 
ATOM   3891  C CG  . LYS B 2 77  ? 93.532  93.640  104.409 1.00 396.03 ? 77  LYS B CG  1 
ATOM   3892  C CD  . LYS B 2 77  ? 94.823  94.420  104.565 1.00 453.96 ? 77  LYS B CD  1 
ATOM   3893  C CE  . LYS B 2 77  ? 95.307  95.072  103.285 1.00 499.72 ? 77  LYS B CE  1 
ATOM   3894  N NZ  . LYS B 2 77  ? 96.546  95.854  103.508 1.00 531.26 ? 77  LYS B NZ  1 
ATOM   3895  N N   . GLU B 2 78  ? 90.571  91.903  102.150 1.00 253.01 ? 78  GLU B N   1 
ATOM   3896  C CA  . GLU B 2 78  ? 89.202  92.355  101.894 1.00 300.12 ? 78  GLU B CA  1 
ATOM   3897  C C   . GLU B 2 78  ? 88.195  91.193  101.925 1.00 326.64 ? 78  GLU B C   1 
ATOM   3898  O O   . GLU B 2 78  ? 87.057  91.381  102.367 1.00 264.47 ? 78  GLU B O   1 
ATOM   3899  C CB  . GLU B 2 78  ? 89.137  93.094  100.548 1.00 294.27 ? 78  GLU B CB  1 
ATOM   3900  C CG  . GLU B 2 78  ? 90.135  94.241  100.356 1.00 304.87 ? 78  GLU B CG  1 
ATOM   3901  C CD  . GLU B 2 78  ? 90.293  95.277  101.463 1.00 314.11 ? 78  GLU B CD  1 
ATOM   3902  O OE1 . GLU B 2 78  ? 89.376  95.427  102.300 1.00 342.72 ? 78  GLU B OE1 1 
ATOM   3903  O OE2 . GLU B 2 78  ? 91.351  95.945  101.482 1.00 300.61 ? 78  GLU B OE2 1 
ATOM   3904  N N   . ALA B 2 79  ? 88.611  90.005  101.448 1.00 356.80 ? 79  ALA B N   1 
ATOM   3905  C CA  . ALA B 2 79  ? 87.770  88.814  101.360 1.00 300.31 ? 79  ALA B CA  1 
ATOM   3906  C C   . ALA B 2 79  ? 87.721  88.036  102.678 1.00 278.50 ? 79  ALA B C   1 
ATOM   3907  O O   . ALA B 2 79  ? 86.819  87.222  102.874 1.00 280.06 ? 79  ALA B O   1 
ATOM   3908  C CB  . ALA B 2 79  ? 88.274  87.926  100.248 1.00 270.11 ? 79  ALA B CB  1 
ATOM   3909  N N   . GLY B 2 80  ? 88.685  88.251  103.583 1.00 270.52 ? 80  GLY B N   1 
ATOM   3910  C CA  . GLY B 2 80  ? 88.583  87.749  104.945 1.00 271.57 ? 80  GLY B CA  1 
ATOM   3911  C C   . GLY B 2 80  ? 89.001  86.287  105.095 1.00 247.55 ? 80  GLY B C   1 
ATOM   3912  O O   . GLY B 2 80  ? 89.627  85.971  106.115 1.00 288.70 ? 80  GLY B O   1 
ATOM   3913  N N   . SER B 2 81  ? 88.667  85.408  104.115 1.00 149.13 ? 81  SER B N   1 
ATOM   3914  C CA  . SER B 2 81  ? 88.948  83.982  104.295 1.00 223.25 ? 81  SER B CA  1 
ATOM   3915  C C   . SER B 2 81  ? 89.372  83.292  103.010 1.00 190.43 ? 81  SER B C   1 
ATOM   3916  O O   . SER B 2 81  ? 89.008  83.777  101.948 1.00 196.91 ? 81  SER B O   1 
ATOM   3917  C CB  . SER B 2 81  ? 87.779  83.244  104.871 1.00 279.64 ? 81  SER B CB  1 
ATOM   3918  O OG  . SER B 2 81  ? 86.748  83.060  103.911 1.00 224.17 ? 81  SER B OG  1 
ATOM   3919  N N   . PRO B 2 82  ? 90.142  82.165  103.079 1.00 221.19 ? 82  PRO B N   1 
ATOM   3920  C CA  . PRO B 2 82  ? 90.616  81.467  101.875 1.00 259.18 ? 82  PRO B CA  1 
ATOM   3921  C C   . PRO B 2 82  ? 89.475  81.052  100.940 1.00 215.41 ? 82  PRO B C   1 
ATOM   3922  O O   . PRO B 2 82  ? 89.649  81.100  99.729  1.00 246.25 ? 82  PRO B O   1 
ATOM   3923  C CB  . PRO B 2 82  ? 91.398  80.240  102.406 1.00 243.66 ? 82  PRO B CB  1 
ATOM   3924  C CG  . PRO B 2 82  ? 91.807  80.666  103.797 1.00 245.68 ? 82  PRO B CG  1 
ATOM   3925  C CD  . PRO B 2 82  ? 90.637  81.495  104.301 1.00 225.53 ? 82  PRO B CD  1 
ATOM   3926  N N   . GLY B 2 83  ? 88.322  80.665  101.497 1.00 251.22 ? 83  GLY B N   1 
ATOM   3927  C CA  . GLY B 2 83  ? 87.155  80.254  100.722 1.00 325.70 ? 83  GLY B CA  1 
ATOM   3928  C C   . GLY B 2 83  ? 86.606  81.314  99.762  1.00 313.99 ? 83  GLY B C   1 
ATOM   3929  O O   . GLY B 2 83  ? 86.141  80.958  98.680  1.00 379.87 ? 83  GLY B O   1 
ATOM   3930  N N   . LEU B 2 84  ? 86.645  82.598  100.157 1.00 277.54 ? 84  LEU B N   1 
ATOM   3931  C CA  . LEU B 2 84  ? 86.230  83.698  99.293  1.00 281.39 ? 84  LEU B CA  1 
ATOM   3932  C C   . LEU B 2 84  ? 87.427  84.262  98.525  1.00 246.88 ? 84  LEU B C   1 
ATOM   3933  O O   . LEU B 2 84  ? 87.282  84.617  97.360  1.00 173.76 ? 84  LEU B O   1 
ATOM   3934  C CB  . LEU B 2 84  ? 85.534  84.789  100.115 1.00 282.11 ? 84  LEU B CB  1 
ATOM   3935  C CG  . LEU B 2 84  ? 84.990  85.973  99.306  1.00 280.76 ? 84  LEU B CG  1 
ATOM   3936  C CD1 . LEU B 2 84  ? 83.953  85.512  98.288  1.00 323.84 ? 84  LEU B CD1 1 
ATOM   3937  C CD2 . LEU B 2 84  ? 84.387  87.038  100.212 1.00 283.43 ? 84  LEU B CD2 1 
ATOM   3938  N N   . ALA B 2 85  ? 88.601  84.345  99.162  1.00 278.27 ? 85  ALA B N   1 
ATOM   3939  C CA  . ALA B 2 85  ? 89.803  84.849  98.511  1.00 284.28 ? 85  ALA B CA  1 
ATOM   3940  C C   . ALA B 2 85  ? 90.131  84.027  97.264  1.00 223.29 ? 85  ALA B C   1 
ATOM   3941  O O   . ALA B 2 85  ? 90.327  84.597  96.186  1.00 301.21 ? 85  ALA B O   1 
ATOM   3942  C CB  . ALA B 2 85  ? 90.959  84.848  99.483  1.00 312.83 ? 85  ALA B CB  1 
ATOM   3943  N N   . LEU B 2 86  ? 90.185  82.694  97.416  1.00 218.30 ? 86  LEU B N   1 
ATOM   3944  C CA  . LEU B 2 86  ? 90.500  81.800  96.310  1.00 247.33 ? 86  LEU B CA  1 
ATOM   3945  C C   . LEU B 2 86  ? 89.373  81.832  95.255  1.00 256.07 ? 86  LEU B C   1 
ATOM   3946  O O   . LEU B 2 86  ? 89.620  81.485  94.094  1.00 253.83 ? 86  LEU B O   1 
ATOM   3947  C CB  . LEU B 2 86  ? 90.792  80.399  96.877  1.00 185.59 ? 86  LEU B CB  1 
ATOM   3948  C CG  . LEU B 2 86  ? 91.476  79.444  95.899  1.00 220.33 ? 86  LEU B CG  1 
ATOM   3949  C CD1 . LEU B 2 86  ? 92.734  78.754  96.462  1.00 171.83 ? 86  LEU B CD1 1 
ATOM   3950  C CD2 . LEU B 2 86  ? 90.450  78.442  95.411  1.00 301.26 ? 86  LEU B CD2 1 
ATOM   3951  N N   . VAL B 2 87  ? 88.154  82.262  95.645  1.00 223.31 ? 87  VAL B N   1 
ATOM   3952  C CA  . VAL B 2 87  ? 87.042  82.441  94.717  1.00 282.64 ? 87  VAL B CA  1 
ATOM   3953  C C   . VAL B 2 87  ? 87.178  83.749  93.927  1.00 278.57 ? 87  VAL B C   1 
ATOM   3954  O O   . VAL B 2 87  ? 86.938  83.683  92.729  1.00 364.29 ? 87  VAL B O   1 
ATOM   3955  C CB  . VAL B 2 87  ? 85.671  82.292  95.420  1.00 341.41 ? 87  VAL B CB  1 
ATOM   3956  C CG1 . VAL B 2 87  ? 84.501  82.983  94.719  1.00 382.38 ? 87  VAL B CG1 1 
ATOM   3957  C CG2 . VAL B 2 87  ? 85.356  80.813  95.612  1.00 332.04 ? 87  VAL B CG2 1 
ATOM   3958  N N   . VAL B 2 88  ? 87.532  84.911  94.517  1.00 236.07 ? 88  VAL B N   1 
ATOM   3959  C CA  . VAL B 2 88  ? 87.672  86.135  93.708  1.00 238.88 ? 88  VAL B CA  1 
ATOM   3960  C C   . VAL B 2 88  ? 88.822  85.990  92.704  1.00 262.62 ? 88  VAL B C   1 
ATOM   3961  O O   . VAL B 2 88  ? 88.757  86.633  91.659  1.00 308.80 ? 88  VAL B O   1 
ATOM   3962  C CB  . VAL B 2 88  ? 87.814  87.460  94.495  1.00 243.38 ? 88  VAL B CB  1 
ATOM   3963  C CG1 . VAL B 2 88  ? 86.531  87.800  95.223  1.00 247.34 ? 88  VAL B CG1 1 
ATOM   3964  C CG2 . VAL B 2 88  ? 88.991  87.483  95.459  1.00 301.92 ? 88  VAL B CG2 1 
ATOM   3965  N N   . TRP B 2 89  ? 89.845  85.159  92.991  1.00 269.27 ? 89  TRP B N   1 
ATOM   3966  C CA  . TRP B 2 89  ? 90.880  84.834  92.006  1.00 262.13 ? 89  TRP B CA  1 
ATOM   3967  C C   . TRP B 2 89  ? 90.319  84.122  90.778  1.00 240.58 ? 89  TRP B C   1 
ATOM   3968  O O   . TRP B 2 89  ? 90.785  84.388  89.667  1.00 335.39 ? 89  TRP B O   1 
ATOM   3969  C CB  . TRP B 2 89  ? 92.022  84.012  92.619  1.00 245.32 ? 89  TRP B CB  1 
ATOM   3970  C CG  . TRP B 2 89  ? 92.983  84.897  93.366  1.00 261.41 ? 89  TRP B CG  1 
ATOM   3971  C CD1 . TRP B 2 89  ? 93.200  84.933  94.712  1.00 295.86 ? 89  TRP B CD1 1 
ATOM   3972  C CD2 . TRP B 2 89  ? 93.865  85.888  92.800  1.00 228.12 ? 89  TRP B CD2 1 
ATOM   3973  N NE1 . TRP B 2 89  ? 94.152  85.865  95.018  1.00 254.69 ? 89  TRP B NE1 1 
ATOM   3974  C CE2 . TRP B 2 89  ? 94.577  86.471  93.868  1.00 249.76 ? 89  TRP B CE2 1 
ATOM   3975  C CE3 . TRP B 2 89  ? 94.124  86.339  91.506  1.00 290.06 ? 89  TRP B CE3 1 
ATOM   3976  C CZ2 . TRP B 2 89  ? 95.528  87.473  93.678  1.00 285.74 ? 89  TRP B CZ2 1 
ATOM   3977  C CZ3 . TRP B 2 89  ? 95.062  87.329  91.320  1.00 311.07 ? 89  TRP B CZ3 1 
ATOM   3978  C CH2 . TRP B 2 89  ? 95.758  87.890  92.389  1.00 272.81 ? 89  TRP B CH2 1 
ATOM   3979  N N   . ALA B 2 90  ? 89.341  83.237  90.968  1.00 174.87 ? 90  ALA B N   1 
ATOM   3980  C CA  . ALA B 2 90  ? 88.652  82.630  89.839  1.00 216.33 ? 90  ALA B CA  1 
ATOM   3981  C C   . ALA B 2 90  ? 87.658  83.610  89.189  1.00 241.55 ? 90  ALA B C   1 
ATOM   3982  O O   . ALA B 2 90  ? 87.610  83.679  87.966  1.00 266.56 ? 90  ALA B O   1 
ATOM   3983  C CB  . ALA B 2 90  ? 87.981  81.365  90.312  1.00 288.87 ? 90  ALA B CB  1 
ATOM   3984  N N   . ALA B 2 91  ? 86.872  84.362  89.985  1.00 223.00 ? 91  ALA B N   1 
ATOM   3985  C CA  . ALA B 2 91  ? 85.857  85.295  89.489  1.00 239.69 ? 91  ALA B CA  1 
ATOM   3986  C C   . ALA B 2 91  ? 86.449  86.388  88.587  1.00 263.82 ? 91  ALA B C   1 
ATOM   3987  O O   . ALA B 2 91  ? 85.905  86.666  87.520  1.00 204.88 ? 91  ALA B O   1 
ATOM   3988  C CB  . ALA B 2 91  ? 85.106  85.904  90.654  1.00 228.34 ? 91  ALA B CB  1 
ATOM   3989  N N   . CYS B 2 92  ? 87.568  86.997  89.003  1.00 295.89 ? 92  CYS B N   1 
ATOM   3990  C CA  . CYS B 2 92  ? 88.286  87.951  88.165  1.00 251.58 ? 92  CYS B CA  1 
ATOM   3991  C C   . CYS B 2 92  ? 88.804  87.281  86.893  1.00 227.92 ? 92  CYS B C   1 
ATOM   3992  O O   . CYS B 2 92  ? 88.823  87.937  85.860  1.00 195.35 ? 92  CYS B O   1 
ATOM   3993  C CB  . CYS B 2 92  ? 89.460  88.566  88.914  1.00 254.38 ? 92  CYS B CB  1 
ATOM   3994  S SG  . CYS B 2 92  ? 88.925  89.481  90.377  1.00 300.62 ? 92  CYS B SG  1 
ATOM   3995  N N   . GLY B 2 93  ? 89.205  85.995  86.975  1.00 195.56 ? 93  GLY B N   1 
ATOM   3996  C CA  . GLY B 2 93  ? 89.537  85.192  85.810  1.00 188.33 ? 93  GLY B CA  1 
ATOM   3997  C C   . GLY B 2 93  ? 88.387  85.148  84.806  1.00 196.40 ? 93  GLY B C   1 
ATOM   3998  O O   . GLY B 2 93  ? 88.591  85.416  83.624  1.00 206.31 ? 93  GLY B O   1 
ATOM   3999  N N   . VAL B 2 94  ? 87.185  84.820  85.290  1.00 183.38 ? 94  VAL B N   1 
ATOM   4000  C CA  . VAL B 2 94  ? 86.004  84.709  84.451  1.00 211.20 ? 94  VAL B CA  1 
ATOM   4001  C C   . VAL B 2 94  ? 85.679  86.070  83.837  1.00 192.38 ? 94  VAL B C   1 
ATOM   4002  O O   . VAL B 2 94  ? 85.487  86.157  82.621  1.00 263.91 ? 94  VAL B O   1 
ATOM   4003  C CB  . VAL B 2 94  ? 84.828  84.096  85.239  1.00 269.80 ? 94  VAL B CB  1 
ATOM   4004  C CG1 . VAL B 2 94  ? 83.453  84.350  84.626  1.00 327.88 ? 94  VAL B CG1 1 
ATOM   4005  C CG2 . VAL B 2 94  ? 85.060  82.600  85.411  1.00 302.26 ? 94  VAL B CG2 1 
ATOM   4006  N N   . PHE B 2 95  ? 85.612  87.118  84.653  1.00 151.23 ? 95  PHE B N   1 
ATOM   4007  C CA  . PHE B 2 95  ? 85.305  88.443  84.130  1.00 164.42 ? 95  PHE B CA  1 
ATOM   4008  C C   . PHE B 2 95  ? 86.317  88.853  83.061  1.00 170.53 ? 95  PHE B C   1 
ATOM   4009  O O   . PHE B 2 95  ? 85.936  89.472  82.068  1.00 171.32 ? 95  PHE B O   1 
ATOM   4010  C CB  . PHE B 2 95  ? 85.259  89.425  85.293  1.00 195.05 ? 95  PHE B CB  1 
ATOM   4011  C CG  . PHE B 2 95  ? 85.129  90.894  84.970  1.00 186.18 ? 95  PHE B CG  1 
ATOM   4012  C CD1 . PHE B 2 95  ? 86.224  91.662  84.556  1.00 226.47 ? 95  PHE B CD1 1 
ATOM   4013  C CD2 . PHE B 2 95  ? 83.909  91.525  85.118  1.00 216.20 ? 95  PHE B CD2 1 
ATOM   4014  C CE1 . PHE B 2 95  ? 86.104  93.021  84.282  1.00 207.48 ? 95  PHE B CE1 1 
ATOM   4015  C CE2 . PHE B 2 95  ? 83.786  92.880  84.853  1.00 252.02 ? 95  PHE B CE2 1 
ATOM   4016  C CZ  . PHE B 2 95  ? 84.878  93.629  84.437  1.00 246.49 ? 95  PHE B CZ  1 
ATOM   4017  N N   . SER B 2 96  ? 87.597  88.508  83.274  1.00 180.75 ? 96  SER B N   1 
ATOM   4018  C CA  . SER B 2 96  ? 88.654  88.767  82.307  1.00 194.92 ? 96  SER B CA  1 
ATOM   4019  C C   . SER B 2 96  ? 88.420  87.958  81.038  1.00 175.32 ? 96  SER B C   1 
ATOM   4020  O O   . SER B 2 96  ? 88.513  88.551  79.967  1.00 161.91 ? 96  SER B O   1 
ATOM   4021  C CB  . SER B 2 96  ? 90.014  88.481  82.883  1.00 232.22 ? 96  SER B CB  1 
ATOM   4022  O OG  . SER B 2 96  ? 90.230  89.232  84.069  1.00 180.02 ? 96  SER B OG  1 
ATOM   4023  N N   . ILE B 2 97  ? 88.128  86.646  81.159  1.00 159.95 ? 97  ILE B N   1 
ATOM   4024  C CA  . ILE B 2 97  ? 87.922  85.782  79.996  1.00 183.80 ? 97  ILE B CA  1 
ATOM   4025  C C   . ILE B 2 97  ? 86.785  86.304  79.122  1.00 169.26 ? 97  ILE B C   1 
ATOM   4026  O O   . ILE B 2 97  ? 86.999  86.422  77.915  1.00 238.09 ? 97  ILE B O   1 
ATOM   4027  C CB  . ILE B 2 97  ? 87.731  84.313  80.407  1.00 214.12 ? 97  ILE B CB  1 
ATOM   4028  C CG1 . ILE B 2 97  ? 89.104  83.658  80.610  1.00 200.57 ? 97  ILE B CG1 1 
ATOM   4029  C CG2 . ILE B 2 97  ? 86.839  83.537  79.428  1.00 201.94 ? 97  ILE B CG2 1 
ATOM   4030  C CD1 . ILE B 2 97  ? 89.060  82.408  81.456  1.00 247.41 ? 97  ILE B CD1 1 
ATOM   4031  N N   . VAL B 2 98  ? 85.625  86.629  79.701  1.00 148.84 ? 98  VAL B N   1 
ATOM   4032  C CA  . VAL B 2 98  ? 84.524  87.124  78.881  1.00 204.59 ? 98  VAL B CA  1 
ATOM   4033  C C   . VAL B 2 98  ? 84.818  88.518  78.298  1.00 211.14 ? 98  VAL B C   1 
ATOM   4034  O O   . VAL B 2 98  ? 84.437  88.783  77.160  1.00 216.53 ? 98  VAL B O   1 
ATOM   4035  C CB  . VAL B 2 98  ? 83.171  87.078  79.623  1.00 241.13 ? 98  VAL B CB  1 
ATOM   4036  C CG1 . VAL B 2 98  ? 82.904  85.662  80.135  1.00 259.31 ? 98  VAL B CG1 1 
ATOM   4037  C CG2 . VAL B 2 98  ? 83.017  88.110  80.731  1.00 197.48 ? 98  VAL B CG2 1 
ATOM   4038  N N   . GLY B 2 99  ? 85.491  89.391  79.056  1.00 167.79 ? 99  GLY B N   1 
ATOM   4039  C CA  . GLY B 2 99  ? 85.994  90.650  78.529  1.00 169.66 ? 99  GLY B CA  1 
ATOM   4040  C C   . GLY B 2 99  ? 87.027  90.500  77.403  1.00 183.05 ? 99  GLY B C   1 
ATOM   4041  O O   . GLY B 2 99  ? 87.000  91.253  76.436  1.00 211.62 ? 99  GLY B O   1 
ATOM   4042  N N   . ALA B 2 100 ? 87.934  89.523  77.521  1.00 204.85 ? 100 ALA B N   1 
ATOM   4043  C CA  . ALA B 2 100 ? 88.996  89.300  76.542  1.00 212.85 ? 100 ALA B CA  1 
ATOM   4044  C C   . ALA B 2 100 ? 88.453  88.713  75.238  1.00 229.46 ? 100 ALA B C   1 
ATOM   4045  O O   . ALA B 2 100 ? 88.813  89.170  74.146  1.00 221.12 ? 100 ALA B O   1 
ATOM   4046  C CB  . ALA B 2 100 ? 90.050  88.407  77.138  1.00 181.75 ? 100 ALA B CB  1 
ATOM   4047  N N   . LEU B 2 101 ? 87.582  87.705  75.343  1.00 229.19 ? 101 LEU B N   1 
ATOM   4048  C CA  . LEU B 2 101 ? 86.880  87.226  74.165  1.00 203.81 ? 101 LEU B CA  1 
ATOM   4049  C C   . LEU B 2 101 ? 86.082  88.352  73.515  1.00 183.85 ? 101 LEU B C   1 
ATOM   4050  O O   . LEU B 2 101 ? 86.051  88.443  72.288  1.00 226.04 ? 101 LEU B O   1 
ATOM   4051  C CB  . LEU B 2 101 ? 85.958  86.083  74.570  1.00 230.93 ? 101 LEU B CB  1 
ATOM   4052  C CG  . LEU B 2 101 ? 86.663  84.741  74.692  1.00 289.28 ? 101 LEU B CG  1 
ATOM   4053  C CD1 . LEU B 2 101 ? 85.683  83.715  75.243  1.00 396.81 ? 101 LEU B CD1 1 
ATOM   4054  C CD2 . LEU B 2 101 ? 87.240  84.308  73.344  1.00 257.25 ? 101 LEU B CD2 1 
ATOM   4055  N N   . CYS B 2 102 ? 85.447  89.201  74.324  1.00 155.11 ? 102 CYS B N   1 
ATOM   4056  C CA  . CYS B 2 102 ? 84.746  90.354  73.788  1.00 198.86 ? 102 CYS B CA  1 
ATOM   4057  C C   . CYS B 2 102 ? 85.716  91.244  72.993  1.00 180.16 ? 102 CYS B C   1 
ATOM   4058  O O   . CYS B 2 102 ? 85.344  91.784  71.950  1.00 201.24 ? 102 CYS B O   1 
ATOM   4059  C CB  . CYS B 2 102 ? 84.018  91.094  74.908  1.00 223.56 ? 102 CYS B CB  1 
ATOM   4060  S SG  . CYS B 2 102 ? 82.622  92.059  74.290  1.00 291.56 ? 102 CYS B SG  1 
ATOM   4061  N N   . TYR B 2 103 ? 86.954  91.385  73.476  1.00 181.29 ? 103 TYR B N   1 
ATOM   4062  C CA  . TYR B 2 103 ? 88.004  92.097  72.759  1.00 200.16 ? 103 TYR B CA  1 
ATOM   4063  C C   . TYR B 2 103 ? 88.466  91.364  71.496  1.00 199.81 ? 103 TYR B C   1 
ATOM   4064  O O   . TYR B 2 103 ? 88.922  92.019  70.571  1.00 228.31 ? 103 TYR B O   1 
ATOM   4065  C CB  . TYR B 2 103 ? 89.166  92.412  73.715  1.00 203.71 ? 103 TYR B CB  1 
ATOM   4066  C CG  . TYR B 2 103 ? 89.101  93.860  74.170  1.00 232.28 ? 103 TYR B CG  1 
ATOM   4067  C CD1 . TYR B 2 103 ? 88.020  94.327  74.911  1.00 237.13 ? 103 TYR B CD1 1 
ATOM   4068  C CD2 . TYR B 2 103 ? 90.104  94.765  73.832  1.00 235.89 ? 103 TYR B CD2 1 
ATOM   4069  C CE1 . TYR B 2 103 ? 87.945  95.648  75.317  1.00 211.77 ? 103 TYR B CE1 1 
ATOM   4070  C CE2 . TYR B 2 103 ? 90.044  96.089  74.234  1.00 242.25 ? 103 TYR B CE2 1 
ATOM   4071  C CZ  . TYR B 2 103 ? 88.960  96.527  74.979  1.00 218.49 ? 103 TYR B CZ  1 
ATOM   4072  O OH  . TYR B 2 103 ? 88.880  97.823  75.380  1.00 223.61 ? 103 TYR B OH  1 
ATOM   4073  N N   . ALA B 2 104 ? 88.369  90.036  71.429  1.00 212.29 ? 104 ALA B N   1 
ATOM   4074  C CA  . ALA B 2 104 ? 88.681  89.315  70.197  1.00 214.21 ? 104 ALA B CA  1 
ATOM   4075  C C   . ALA B 2 104 ? 87.641  89.586  69.092  1.00 200.12 ? 104 ALA B C   1 
ATOM   4076  O O   . ALA B 2 104 ? 88.015  89.704  67.918  1.00 162.30 ? 104 ALA B O   1 
ATOM   4077  C CB  . ALA B 2 104 ? 88.795  87.859  70.533  1.00 237.39 ? 104 ALA B CB  1 
ATOM   4078  N N   . GLU B 2 105 ? 86.341  89.688  69.455  1.00 183.59 ? 105 GLU B N   1 
ATOM   4079  C CA  . GLU B 2 105 ? 85.291  90.103  68.529  1.00 230.90 ? 105 GLU B CA  1 
ATOM   4080  C C   . GLU B 2 105 ? 85.577  91.521  68.028  1.00 209.60 ? 105 GLU B C   1 
ATOM   4081  O O   . GLU B 2 105 ? 85.613  91.755  66.819  1.00 215.04 ? 105 GLU B O   1 
ATOM   4082  C CB  . GLU B 2 105 ? 83.893  90.041  69.169  1.00 277.75 ? 105 GLU B CB  1 
ATOM   4083  C CG  . GLU B 2 105 ? 83.350  88.634  69.415  1.00 352.94 ? 105 GLU B CG  1 
ATOM   4084  C CD  . GLU B 2 105 ? 81.902  88.596  69.897  1.00 343.08 ? 105 GLU B CD  1 
ATOM   4085  O OE1 . GLU B 2 105 ? 81.680  88.792  71.105  1.00 301.20 ? 105 GLU B OE1 1 
ATOM   4086  O OE2 . GLU B 2 105 ? 80.993  88.383  69.067  1.00 328.19 ? 105 GLU B OE2 1 
ATOM   4087  N N   . LEU B 2 106 ? 85.779  92.455  68.964  1.00 213.78 ? 106 LEU B N   1 
ATOM   4088  C CA  . LEU B 2 106 ? 85.951  93.868  68.635  1.00 229.73 ? 106 LEU B CA  1 
ATOM   4089  C C   . LEU B 2 106 ? 87.227  94.093  67.818  1.00 192.83 ? 106 LEU B C   1 
ATOM   4090  O O   . LEU B 2 106 ? 87.246  94.900  66.882  1.00 221.14 ? 106 LEU B O   1 
ATOM   4091  C CB  . LEU B 2 106 ? 85.949  94.667  69.942  1.00 231.51 ? 106 LEU B CB  1 
ATOM   4092  C CG  . LEU B 2 106 ? 86.018  96.191  69.838  1.00 221.71 ? 106 LEU B CG  1 
ATOM   4093  C CD1 . LEU B 2 106 ? 84.892  96.806  69.021  1.00 198.05 ? 106 LEU B CD1 1 
ATOM   4094  C CD2 . LEU B 2 106 ? 85.993  96.786  71.230  1.00 260.09 ? 106 LEU B CD2 1 
ATOM   4095  N N   . GLY B 2 107 ? 88.281  93.362  68.162  1.00 169.22 ? 107 GLY B N   1 
ATOM   4096  C CA  . GLY B 2 107 ? 89.540  93.485  67.458  1.00 215.66 ? 107 GLY B CA  1 
ATOM   4097  C C   . GLY B 2 107 ? 89.535  92.931  66.036  1.00 243.52 ? 107 GLY B C   1 
ATOM   4098  O O   . GLY B 2 107 ? 90.055  93.584  65.136  1.00 229.23 ? 107 GLY B O   1 
ATOM   4099  N N   . THR B 2 108 ? 88.969  91.736  65.825  1.00 235.44 ? 108 THR B N   1 
ATOM   4100  C CA  . THR B 2 108 ? 88.889  91.189  64.477  1.00 234.12 ? 108 THR B CA  1 
ATOM   4101  C C   . THR B 2 108 ? 87.876  91.968  63.639  1.00 228.27 ? 108 THR B C   1 
ATOM   4102  O O   . THR B 2 108 ? 87.999  91.938  62.413  1.00 235.81 ? 108 THR B O   1 
ATOM   4103  C CB  . THR B 2 108 ? 88.576  89.689  64.472  1.00 265.13 ? 108 THR B CB  1 
ATOM   4104  O OG1 . THR B 2 108 ? 87.419  89.429  65.271  1.00 288.59 ? 108 THR B OG1 1 
ATOM   4105  C CG2 . THR B 2 108 ? 89.750  88.867  64.955  1.00 252.85 ? 108 THR B CG2 1 
ATOM   4106  N N   . THR B 2 109 ? 86.896  92.641  64.282  1.00 232.83 ? 109 THR B N   1 
ATOM   4107  C CA  . THR B 2 109 ? 85.982  93.557  63.604  1.00 235.08 ? 109 THR B CA  1 
ATOM   4108  C C   . THR B 2 109 ? 86.750  94.711  62.953  1.00 220.20 ? 109 THR B C   1 
ATOM   4109  O O   . THR B 2 109 ? 86.695  94.866  61.733  1.00 207.93 ? 109 THR B O   1 
ATOM   4110  C CB  . THR B 2 109 ? 84.888  94.082  64.557  1.00 251.37 ? 109 THR B CB  1 
ATOM   4111  O OG1 . THR B 2 109 ? 84.078  92.986  64.991  1.00 311.23 ? 109 THR B OG1 1 
ATOM   4112  C CG2 . THR B 2 109 ? 83.960  95.121  63.962  1.00 250.14 ? 109 THR B CG2 1 
ATOM   4113  N N   . ILE B 2 110 ? 87.448  95.518  63.768  1.00 227.87 ? 110 ILE B N   1 
ATOM   4114  C CA  . ILE B 2 110 ? 87.947  96.819  63.331  1.00 234.73 ? 110 ILE B CA  1 
ATOM   4115  C C   . ILE B 2 110 ? 89.390  96.695  62.809  1.00 244.93 ? 110 ILE B C   1 
ATOM   4116  O O   . ILE B 2 110 ? 89.744  97.408  61.873  1.00 277.64 ? 110 ILE B O   1 
ATOM   4117  C CB  . ILE B 2 110 ? 87.757  97.874  64.451  1.00 252.50 ? 110 ILE B CB  1 
ATOM   4118  C CG1 . ILE B 2 110 ? 86.272  98.010  64.828  1.00 277.48 ? 110 ILE B CG1 1 
ATOM   4119  C CG2 . ILE B 2 110 ? 88.349  99.229  64.059  1.00 221.04 ? 110 ILE B CG2 1 
ATOM   4120  C CD1 . ILE B 2 110 ? 85.969  98.906  66.020  1.00 339.92 ? 110 ILE B CD1 1 
ATOM   4121  N N   . SER B 2 111 ? 90.225  95.829  63.418  1.00 246.88 ? 111 SER B N   1 
ATOM   4122  C CA  . SER B 2 111 ? 91.560  95.423  62.949  1.00 289.89 ? 111 SER B CA  1 
ATOM   4123  C C   . SER B 2 111 ? 92.603  96.556  62.848  1.00 302.73 ? 111 SER B C   1 
ATOM   4124  O O   . SER B 2 111 ? 93.715  96.315  62.367  1.00 283.52 ? 111 SER B O   1 
ATOM   4125  C CB  . SER B 2 111 ? 91.489  94.646  61.647  1.00 306.70 ? 111 SER B CB  1 
ATOM   4126  O OG  . SER B 2 111 ? 92.739  94.014  61.383  1.00 283.56 ? 111 SER B OG  1 
ATOM   4127  N N   . LYS B 2 112 ? 92.299  97.782  63.306  1.00 295.72 ? 112 LYS B N   1 
ATOM   4128  C CA  . LYS B 2 112 ? 93.338  98.759  63.603  1.00 270.34 ? 112 LYS B CA  1 
ATOM   4129  C C   . LYS B 2 112 ? 94.124  98.325  64.844  1.00 260.19 ? 112 LYS B C   1 
ATOM   4130  O O   . LYS B 2 112 ? 93.593  97.645  65.725  1.00 239.54 ? 112 LYS B O   1 
ATOM   4131  C CB  . LYS B 2 112 ? 92.741  100.145 63.851  1.00 257.45 ? 112 LYS B CB  1 
ATOM   4132  C CG  . LYS B 2 112 ? 92.169  100.831 62.624  1.00 294.45 ? 112 LYS B CG  1 
ATOM   4133  C CD  . LYS B 2 112 ? 91.520  102.159 62.947  1.00 362.50 ? 112 LYS B CD  1 
ATOM   4134  C CE  . LYS B 2 112 ? 91.046  102.916 61.723  1.00 439.31 ? 112 LYS B CE  1 
ATOM   4135  N NZ  . LYS B 2 112 ? 92.173  103.482 60.940  1.00 475.73 ? 112 LYS B NZ  1 
ATOM   4136  N N   . SER B 2 113 ? 95.401  98.738  64.905  1.00 256.22 ? 113 SER B N   1 
ATOM   4137  C CA  . SER B 2 113 ? 96.192  98.730  66.130  1.00 232.43 ? 113 SER B CA  1 
ATOM   4138  C C   . SER B 2 113 ? 95.756  99.923  66.977  1.00 235.87 ? 113 SER B C   1 
ATOM   4139  O O   . SER B 2 113 ? 94.876  100.685 66.575  1.00 261.28 ? 113 SER B O   1 
ATOM   4140  C CB  . SER B 2 113 ? 97.677  98.735  65.847  1.00 232.64 ? 113 SER B CB  1 
ATOM   4141  O OG  . SER B 2 113 ? 98.070  99.885  65.114  1.00 296.22 ? 113 SER B OG  1 
ATOM   4142  N N   . GLY B 2 114 ? 96.353  100.076 68.163  1.00 238.67 ? 114 GLY B N   1 
ATOM   4143  C CA  . GLY B 2 114 ? 95.904  101.070 69.123  1.00 274.17 ? 114 GLY B CA  1 
ATOM   4144  C C   . GLY B 2 114 ? 94.646  100.671 69.904  1.00 229.35 ? 114 GLY B C   1 
ATOM   4145  O O   . GLY B 2 114 ? 94.116  101.498 70.639  1.00 210.04 ? 114 GLY B O   1 
ATOM   4146  N N   . GLY B 2 115 ? 94.171  99.427  69.757  1.00 202.19 ? 115 GLY B N   1 
ATOM   4147  C CA  . GLY B 2 115 ? 93.344  98.762  70.752  1.00 206.52 ? 115 GLY B CA  1 
ATOM   4148  C C   . GLY B 2 115 ? 92.113  99.561  71.186  1.00 205.05 ? 115 GLY B C   1 
ATOM   4149  O O   . GLY B 2 115 ? 91.380  100.113 70.365  1.00 197.55 ? 115 GLY B O   1 
ATOM   4150  N N   . ASP B 2 116 ? 91.913  99.596  72.501  1.00 185.17 ? 116 ASP B N   1 
ATOM   4151  C CA  . ASP B 2 116 ? 90.819  100.293 73.156  1.00 216.83 ? 116 ASP B CA  1 
ATOM   4152  C C   . ASP B 2 116 ? 90.613  101.699 72.582  1.00 221.99 ? 116 ASP B C   1 
ATOM   4153  O O   . ASP B 2 116 ? 89.490  102.049 72.224  1.00 252.15 ? 116 ASP B O   1 
ATOM   4154  C CB  . ASP B 2 116 ? 91.135  100.263 74.655  1.00 282.57 ? 116 ASP B CB  1 
ATOM   4155  C CG  . ASP B 2 116 ? 90.191  100.975 75.605  1.00 286.84 ? 116 ASP B CG  1 
ATOM   4156  O OD1 . ASP B 2 116 ? 89.235  101.619 75.142  1.00 288.87 ? 116 ASP B OD1 1 
ATOM   4157  O OD2 . ASP B 2 116 ? 90.444  100.875 76.822  1.00 276.06 ? 116 ASP B OD2 1 
ATOM   4158  N N   . TYR B 2 117 ? 91.688  102.492 72.497  1.00 219.11 ? 117 TYR B N   1 
ATOM   4159  C CA  . TYR B 2 117 ? 91.655  103.839 71.935  1.00 227.21 ? 117 TYR B CA  1 
ATOM   4160  C C   . TYR B 2 117 ? 91.140  103.876 70.487  1.00 212.61 ? 117 TYR B C   1 
ATOM   4161  O O   . TYR B 2 117 ? 90.271  104.692 70.172  1.00 194.51 ? 117 TYR B O   1 
ATOM   4162  C CB  . TYR B 2 117 ? 93.053  104.449 72.024  1.00 217.57 ? 117 TYR B CB  1 
ATOM   4163  C CG  . TYR B 2 117 ? 93.271  105.635 71.101  1.00 237.99 ? 117 TYR B CG  1 
ATOM   4164  C CD1 . TYR B 2 117 ? 92.688  106.858 71.404  1.00 218.06 ? 117 TYR B CD1 1 
ATOM   4165  C CD2 . TYR B 2 117 ? 94.043  105.531 69.933  1.00 221.37 ? 117 TYR B CD2 1 
ATOM   4166  C CE1 . TYR B 2 117 ? 92.876  107.960 70.582  1.00 238.48 ? 117 TYR B CE1 1 
ATOM   4167  C CE2 . TYR B 2 117 ? 94.236  106.624 69.100  1.00 195.54 ? 117 TYR B CE2 1 
ATOM   4168  C CZ  . TYR B 2 117 ? 93.649  107.839 69.431  1.00 262.94 ? 117 TYR B CZ  1 
ATOM   4169  O OH  . TYR B 2 117 ? 93.825  108.928 68.629  1.00 328.56 ? 117 TYR B OH  1 
ATOM   4170  N N   . ALA B 2 118 ? 91.668  103.009 69.612  1.00 188.13 ? 118 ALA B N   1 
ATOM   4171  C CA  . ALA B 2 118 ? 91.218  102.925 68.226  1.00 208.78 ? 118 ALA B CA  1 
ATOM   4172  C C   . ALA B 2 118 ? 89.737  102.559 68.142  1.00 217.10 ? 118 ALA B C   1 
ATOM   4173  O O   . ALA B 2 118 ? 88.977  103.205 67.408  1.00 279.62 ? 118 ALA B O   1 
ATOM   4174  C CB  . ALA B 2 118 ? 92.042  101.919 67.464  1.00 208.49 ? 118 ALA B CB  1 
ATOM   4175  N N   . TYR B 2 119 ? 89.338  101.528 68.899  1.00 174.24 ? 119 TYR B N   1 
ATOM   4176  C CA  . TYR B 2 119 ? 87.963  101.041 68.876  1.00 189.64 ? 119 TYR B CA  1 
ATOM   4177  C C   . TYR B 2 119 ? 86.998  102.074 69.451  1.00 202.71 ? 119 TYR B C   1 
ATOM   4178  O O   . TYR B 2 119 ? 85.846  102.120 69.032  1.00 196.92 ? 119 TYR B O   1 
ATOM   4179  C CB  . TYR B 2 119 ? 87.856  99.717  69.631  1.00 159.60 ? 119 TYR B CB  1 
ATOM   4180  C CG  . TYR B 2 119 ? 88.873  98.672  69.200  1.00 191.65 ? 119 TYR B CG  1 
ATOM   4181  C CD1 . TYR B 2 119 ? 89.439  98.661  67.919  1.00 216.76 ? 119 TYR B CD1 1 
ATOM   4182  C CD2 . TYR B 2 119 ? 89.277  97.691  70.102  1.00 241.50 ? 119 TYR B CD2 1 
ATOM   4183  C CE1 . TYR B 2 119 ? 90.368  97.697  67.560  1.00 259.48 ? 119 TYR B CE1 1 
ATOM   4184  C CE2 . TYR B 2 119 ? 90.203  96.723  69.752  1.00 227.32 ? 119 TYR B CE2 1 
ATOM   4185  C CZ  . TYR B 2 119 ? 90.755  96.733  68.480  1.00 238.22 ? 119 TYR B CZ  1 
ATOM   4186  O OH  . TYR B 2 119 ? 91.677  95.797  68.116  1.00 177.91 ? 119 TYR B OH  1 
ATOM   4187  N N   . MET B 2 120 ? 87.474  102.891 70.399  1.00 234.63 ? 120 MET B N   1 
ATOM   4188  C CA  . MET B 2 120 ? 86.697  104.002 70.915  1.00 248.20 ? 120 MET B CA  1 
ATOM   4189  C C   . MET B 2 120 ? 86.553  105.092 69.848  1.00 257.87 ? 120 MET B C   1 
ATOM   4190  O O   . MET B 2 120 ? 85.454  105.628 69.717  1.00 347.21 ? 120 MET B O   1 
ATOM   4191  C CB  . MET B 2 120 ? 87.320  104.582 72.187  1.00 206.99 ? 120 MET B CB  1 
ATOM   4192  C CG  . MET B 2 120 ? 86.504  105.727 72.760  1.00 213.58 ? 120 MET B CG  1 
ATOM   4193  S SD  . MET B 2 120 ? 86.902  106.140 74.453  1.00 293.70 ? 120 MET B SD  1 
ATOM   4194  C CE  . MET B 2 120 ? 86.402  104.593 75.211  1.00 236.00 ? 120 MET B CE  1 
ATOM   4195  N N   . LEU B 2 121 ? 87.617  105.415 69.092  1.00 207.33 ? 121 LEU B N   1 
ATOM   4196  C CA  . LEU B 2 121 ? 87.537  106.478 68.088  1.00 275.89 ? 121 LEU B CA  1 
ATOM   4197  C C   . LEU B 2 121 ? 86.509  106.145 66.989  1.00 291.14 ? 121 LEU B C   1 
ATOM   4198  O O   . LEU B 2 121 ? 85.772  107.030 66.537  1.00 221.32 ? 121 LEU B O   1 
ATOM   4199  C CB  . LEU B 2 121 ? 88.943  106.738 67.525  1.00 289.79 ? 121 LEU B CB  1 
ATOM   4200  C CG  . LEU B 2 121 ? 89.065  107.838 66.463  1.00 297.55 ? 121 LEU B CG  1 
ATOM   4201  C CD1 . LEU B 2 121 ? 88.494  109.173 66.938  1.00 276.73 ? 121 LEU B CD1 1 
ATOM   4202  C CD2 . LEU B 2 121 ? 90.517  108.027 66.045  1.00 279.14 ? 121 LEU B CD2 1 
ATOM   4203  N N   . GLU B 2 122 ? 86.440  104.867 66.576  1.00 280.04 ? 122 GLU B N   1 
ATOM   4204  C CA  . GLU B 2 122 ? 85.488  104.404 65.570  1.00 251.50 ? 122 GLU B CA  1 
ATOM   4205  C C   . GLU B 2 122 ? 84.030  104.412 66.035  1.00 228.84 ? 122 GLU B C   1 
ATOM   4206  O O   . GLU B 2 122 ? 83.162  104.178 65.197  1.00 288.48 ? 122 GLU B O   1 
ATOM   4207  C CB  . GLU B 2 122 ? 85.854  102.986 65.117  1.00 292.23 ? 122 GLU B CB  1 
ATOM   4208  C CG  . GLU B 2 122 ? 87.146  102.934 64.318  1.00 399.93 ? 122 GLU B CG  1 
ATOM   4209  C CD  . GLU B 2 122 ? 87.141  103.731 63.022  1.00 485.43 ? 122 GLU B CD  1 
ATOM   4210  O OE1 . GLU B 2 122 ? 86.047  103.932 62.450  1.00 537.13 ? 122 GLU B OE1 1 
ATOM   4211  O OE2 . GLU B 2 122 ? 88.224  104.160 62.594  1.00 499.94 ? 122 GLU B OE2 1 
ATOM   4212  N N   . VAL B 2 123 ? 83.746  104.667 67.327  1.00 243.26 ? 123 VAL B N   1 
ATOM   4213  C CA  . VAL B 2 123 ? 82.385  104.646 67.864  1.00 269.58 ? 123 VAL B CA  1 
ATOM   4214  C C   . VAL B 2 123 ? 81.997  105.981 68.510  1.00 232.32 ? 123 VAL B C   1 
ATOM   4215  O O   . VAL B 2 123 ? 80.914  106.501 68.215  1.00 267.87 ? 123 VAL B O   1 
ATOM   4216  C CB  . VAL B 2 123 ? 82.209  103.474 68.851  1.00 268.00 ? 123 VAL B CB  1 
ATOM   4217  C CG1 . VAL B 2 123 ? 80.879  103.541 69.598  1.00 273.83 ? 123 VAL B CG1 1 
ATOM   4218  C CG2 . VAL B 2 123 ? 82.350  102.138 68.138  1.00 287.35 ? 123 VAL B CG2 1 
ATOM   4219  N N   . TYR B 2 124 ? 82.858  106.506 69.393  1.00 202.08 ? 124 TYR B N   1 
ATOM   4220  C CA  . TYR B 2 124 ? 82.569  107.710 70.166  1.00 248.17 ? 124 TYR B CA  1 
ATOM   4221  C C   . TYR B 2 124 ? 83.169  108.977 69.542  1.00 268.68 ? 124 TYR B C   1 
ATOM   4222  O O   . TYR B 2 124 ? 82.804  110.073 69.967  1.00 272.53 ? 124 TYR B O   1 
ATOM   4223  C CB  . TYR B 2 124 ? 83.059  107.498 71.603  1.00 247.10 ? 124 TYR B CB  1 
ATOM   4224  C CG  . TYR B 2 124 ? 82.360  106.359 72.333  1.00 308.85 ? 124 TYR B CG  1 
ATOM   4225  C CD1 . TYR B 2 124 ? 82.795  105.039 72.197  1.00 369.09 ? 124 TYR B CD1 1 
ATOM   4226  C CD2 . TYR B 2 124 ? 81.260  106.597 73.154  1.00 302.57 ? 124 TYR B CD2 1 
ATOM   4227  C CE1 . TYR B 2 124 ? 82.159  103.994 72.853  1.00 339.18 ? 124 TYR B CE1 1 
ATOM   4228  C CE2 . TYR B 2 124 ? 80.617  105.560 73.816  1.00 312.85 ? 124 TYR B CE2 1 
ATOM   4229  C CZ  . TYR B 2 124 ? 81.067  104.256 73.665  1.00 305.87 ? 124 TYR B CZ  1 
ATOM   4230  O OH  . TYR B 2 124 ? 80.452  103.220 74.304  1.00 259.07 ? 124 TYR B OH  1 
ATOM   4231  N N   . GLY B 2 125 ? 84.069  108.856 68.554  1.00 255.85 ? 125 GLY B N   1 
ATOM   4232  C CA  . GLY B 2 125 ? 84.627  110.019 67.879  1.00 261.39 ? 125 GLY B CA  1 
ATOM   4233  C C   . GLY B 2 125 ? 85.732  110.718 68.678  1.00 252.30 ? 125 GLY B C   1 
ATOM   4234  O O   . GLY B 2 125 ? 86.242  110.179 69.662  1.00 262.62 ? 125 GLY B O   1 
ATOM   4235  N N   . SER B 2 126 ? 86.085  111.939 68.237  1.00 258.87 ? 126 SER B N   1 
ATOM   4236  C CA  . SER B 2 126 ? 87.387  112.547 68.497  1.00 252.28 ? 126 SER B CA  1 
ATOM   4237  C C   . SER B 2 126 ? 87.608  112.841 69.983  1.00 219.99 ? 126 SER B C   1 
ATOM   4238  O O   . SER B 2 126 ? 88.584  112.350 70.556  1.00 288.23 ? 126 SER B O   1 
ATOM   4239  C CB  . SER B 2 126 ? 87.585  113.786 67.651  1.00 242.94 ? 126 SER B CB  1 
ATOM   4240  O OG  . SER B 2 126 ? 88.825  114.417 67.942  1.00 209.07 ? 126 SER B OG  1 
ATOM   4241  N N   . LEU B 2 127 ? 86.722  113.613 70.620  1.00 189.63 ? 127 LEU B N   1 
ATOM   4242  C CA  . LEU B 2 127 ? 87.000  114.063 71.979  1.00 226.88 ? 127 LEU B CA  1 
ATOM   4243  C C   . LEU B 2 127 ? 87.006  112.873 72.945  1.00 227.57 ? 127 LEU B C   1 
ATOM   4244  O O   . LEU B 2 127 ? 87.954  112.775 73.721  1.00 268.67 ? 127 LEU B O   1 
ATOM   4245  C CB  . LEU B 2 127 ? 86.025  115.177 72.407  1.00 291.27 ? 127 LEU B CB  1 
ATOM   4246  C CG  . LEU B 2 127 ? 85.993  115.527 73.901  1.00 299.23 ? 127 LEU B CG  1 
ATOM   4247  C CD1 . LEU B 2 127 ? 87.330  116.094 74.369  1.00 275.31 ? 127 LEU B CD1 1 
ATOM   4248  C CD2 . LEU B 2 127 ? 84.861  116.497 74.213  1.00 319.17 ? 127 LEU B CD2 1 
ATOM   4249  N N   . PRO B 2 128 ? 86.002  111.955 72.970  1.00 241.24 ? 128 PRO B N   1 
ATOM   4250  C CA  . PRO B 2 128 ? 86.072  110.774 73.847  1.00 290.17 ? 128 PRO B CA  1 
ATOM   4251  C C   . PRO B 2 128 ? 87.357  109.951 73.709  1.00 244.83 ? 128 PRO B C   1 
ATOM   4252  O O   . PRO B 2 128 ? 87.963  109.592 74.717  1.00 163.09 ? 128 PRO B O   1 
ATOM   4253  C CB  . PRO B 2 128 ? 84.826  109.980 73.428  1.00 286.67 ? 128 PRO B CB  1 
ATOM   4254  C CG  . PRO B 2 128 ? 83.867  111.055 73.003  1.00 253.26 ? 128 PRO B CG  1 
ATOM   4255  C CD  . PRO B 2 128 ? 84.740  111.996 72.208  1.00 209.17 ? 128 PRO B CD  1 
ATOM   4256  N N   . ALA B 2 129 ? 87.769  109.681 72.467  1.00 211.71 ? 129 ALA B N   1 
ATOM   4257  C CA  . ALA B 2 129 ? 89.000  108.952 72.206  1.00 203.70 ? 129 ALA B CA  1 
ATOM   4258  C C   . ALA B 2 129 ? 90.229  109.731 72.695  1.00 207.93 ? 129 ALA B C   1 
ATOM   4259  O O   . ALA B 2 129 ? 91.147  109.116 73.237  1.00 265.02 ? 129 ALA B O   1 
ATOM   4260  C CB  . ALA B 2 129 ? 89.082  108.612 70.737  1.00 209.93 ? 129 ALA B CB  1 
ATOM   4261  N N   . PHE B 2 130 ? 90.263  111.063 72.534  1.00 172.55 ? 130 PHE B N   1 
ATOM   4262  C CA  . PHE B 2 130 ? 91.403  111.819 73.031  1.00 173.81 ? 130 PHE B CA  1 
ATOM   4263  C C   . PHE B 2 130 ? 91.460  111.749 74.562  1.00 214.35 ? 130 PHE B C   1 
ATOM   4264  O O   . PHE B 2 130 ? 92.540  111.523 75.100  1.00 231.54 ? 130 PHE B O   1 
ATOM   4265  C CB  . PHE B 2 130 ? 91.400  113.281 72.602  1.00 189.79 ? 130 PHE B CB  1 
ATOM   4266  C CG  . PHE B 2 130 ? 92.536  114.059 73.226  1.00 239.06 ? 130 PHE B CG  1 
ATOM   4267  C CD1 . PHE B 2 130 ? 93.787  114.093 72.615  1.00 210.57 ? 130 PHE B CD1 1 
ATOM   4268  C CD2 . PHE B 2 130 ? 92.365  114.747 74.433  1.00 222.22 ? 130 PHE B CD2 1 
ATOM   4269  C CE1 . PHE B 2 130 ? 94.840  114.806 73.178  1.00 231.56 ? 130 PHE B CE1 1 
ATOM   4270  C CE2 . PHE B 2 130 ? 93.421  115.450 75.004  1.00 227.69 ? 130 PHE B CE2 1 
ATOM   4271  C CZ  . PHE B 2 130 ? 94.656  115.479 74.375  1.00 264.09 ? 130 PHE B CZ  1 
ATOM   4272  N N   . LEU B 2 131 ? 90.335  111.934 75.269  1.00 214.13 ? 131 LEU B N   1 
ATOM   4273  C CA  . LEU B 2 131 ? 90.379  111.882 76.724  1.00 217.08 ? 131 LEU B CA  1 
ATOM   4274  C C   . LEU B 2 131 ? 90.852  110.503 77.179  1.00 256.73 ? 131 LEU B C   1 
ATOM   4275  O O   . LEU B 2 131 ? 91.644  110.428 78.111  1.00 316.60 ? 131 LEU B O   1 
ATOM   4276  C CB  . LEU B 2 131 ? 89.008  112.209 77.323  1.00 244.13 ? 131 LEU B CB  1 
ATOM   4277  C CG  . LEU B 2 131 ? 88.513  113.634 77.112  1.00 326.45 ? 131 LEU B CG  1 
ATOM   4278  C CD1 . LEU B 2 131 ? 87.204  113.833 77.864  1.00 388.64 ? 131 LEU B CD1 1 
ATOM   4279  C CD2 . LEU B 2 131 ? 89.555  114.664 77.542  1.00 313.48 ? 131 LEU B CD2 1 
ATOM   4280  N N   . LYS B 2 132 ? 90.374  109.435 76.526  1.00 223.86 ? 132 LYS B N   1 
ATOM   4281  C CA  . LYS B 2 132 ? 90.843  108.079 76.778  1.00 201.38 ? 132 LYS B CA  1 
ATOM   4282  C C   . LYS B 2 132 ? 92.364  108.021 76.689  1.00 172.12 ? 132 LYS B C   1 
ATOM   4283  O O   . LYS B 2 132 ? 93.002  107.471 77.583  1.00 153.77 ? 132 LYS B O   1 
ATOM   4284  C CB  . LYS B 2 132 ? 90.164  107.101 75.803  1.00 224.57 ? 132 LYS B CB  1 
ATOM   4285  C CG  . LYS B 2 132 ? 90.860  105.775 75.511  1.00 196.77 ? 132 LYS B CG  1 
ATOM   4286  C CD  . LYS B 2 132 ? 90.932  104.897 76.708  1.00 248.33 ? 132 LYS B CD  1 
ATOM   4287  C CE  . LYS B 2 132 ? 91.936  103.789 76.512  1.00 273.22 ? 132 LYS B CE  1 
ATOM   4288  N NZ  . LYS B 2 132 ? 91.994  102.891 77.692  1.00 327.35 ? 132 LYS B NZ  1 
ATOM   4289  N N   . LEU B 2 133 ? 92.931  108.565 75.608  1.00 181.03 ? 133 LEU B N   1 
ATOM   4290  C CA  . LEU B 2 133 ? 94.364  108.468 75.396  1.00 176.98 ? 133 LEU B CA  1 
ATOM   4291  C C   . LEU B 2 133 ? 95.108  109.402 76.351  1.00 152.78 ? 133 LEU B C   1 
ATOM   4292  O O   . LEU B 2 133 ? 96.171  109.018 76.824  1.00 231.97 ? 133 LEU B O   1 
ATOM   4293  C CB  . LEU B 2 133 ? 94.676  108.746 73.928  1.00 172.51 ? 133 LEU B CB  1 
ATOM   4294  C CG  . LEU B 2 133 ? 96.157  108.667 73.575  1.00 191.26 ? 133 LEU B CG  1 
ATOM   4295  C CD1 . LEU B 2 133 ? 96.347  108.045 72.208  1.00 202.04 ? 133 LEU B CD1 1 
ATOM   4296  C CD2 . LEU B 2 133 ? 96.826  110.047 73.622  1.00 200.13 ? 133 LEU B CD2 1 
ATOM   4297  N N   . TRP B 2 134 ? 94.576  110.582 76.653  1.00 127.60 ? 134 TRP B N   1 
ATOM   4298  C CA  . TRP B 2 134 ? 95.208  111.478 77.609  1.00 192.54 ? 134 TRP B CA  1 
ATOM   4299  C C   . TRP B 2 134 ? 95.373  110.861 79.014  1.00 257.33 ? 134 TRP B C   1 
ATOM   4300  O O   . TRP B 2 134 ? 96.402  111.064 79.664  1.00 313.42 ? 134 TRP B O   1 
ATOM   4301  C CB  . TRP B 2 134 ? 94.377  112.762 77.670  1.00 233.78 ? 134 TRP B CB  1 
ATOM   4302  C CG  . TRP B 2 134 ? 94.942  113.839 78.557  1.00 242.99 ? 134 TRP B CG  1 
ATOM   4303  C CD1 . TRP B 2 134 ? 94.398  114.311 79.718  1.00 221.79 ? 134 TRP B CD1 1 
ATOM   4304  C CD2 . TRP B 2 134 ? 96.167  114.576 78.343  1.00 235.31 ? 134 TRP B CD2 1 
ATOM   4305  N NE1 . TRP B 2 134 ? 95.191  115.299 80.240  1.00 241.58 ? 134 TRP B NE1 1 
ATOM   4306  C CE2 . TRP B 2 134 ? 96.286  115.483 79.425  1.00 258.15 ? 134 TRP B CE2 1 
ATOM   4307  C CE3 . TRP B 2 134 ? 97.162  114.554 77.349  1.00 211.15 ? 134 TRP B CE3 1 
ATOM   4308  C CZ2 . TRP B 2 134 ? 97.371  116.365 79.531  1.00 303.79 ? 134 TRP B CZ2 1 
ATOM   4309  C CZ3 . TRP B 2 134 ? 98.233  115.423 77.460  1.00 264.99 ? 134 TRP B CZ3 1 
ATOM   4310  C CH2 . TRP B 2 134 ? 98.334  116.314 78.539  1.00 316.15 ? 134 TRP B CH2 1 
ATOM   4311  N N   . ILE B 2 135 ? 94.372  110.112 79.497  1.00 224.39 ? 135 ILE B N   1 
ATOM   4312  C CA  . ILE B 2 135 ? 94.483  109.342 80.729  1.00 211.27 ? 135 ILE B CA  1 
ATOM   4313  C C   . ILE B 2 135 ? 95.628  108.322 80.593  1.00 230.95 ? 135 ILE B C   1 
ATOM   4314  O O   . ILE B 2 135 ? 96.404  108.155 81.521  1.00 199.40 ? 135 ILE B O   1 
ATOM   4315  C CB  . ILE B 2 135 ? 93.122  108.686 81.063  1.00 252.37 ? 135 ILE B CB  1 
ATOM   4316  C CG1 . ILE B 2 135 ? 92.027  109.719 81.338  1.00 367.39 ? 135 ILE B CG1 1 
ATOM   4317  C CG2 . ILE B 2 135 ? 93.210  107.714 82.227  1.00 293.19 ? 135 ILE B CG2 1 
ATOM   4318  C CD1 . ILE B 2 135 ? 90.621  109.182 81.129  1.00 436.06 ? 135 ILE B CD1 1 
ATOM   4319  N N   . GLU B 2 136 ? 95.769  107.626 79.455  1.00 227.59 ? 136 GLU B N   1 
ATOM   4320  C CA  . GLU B 2 136 ? 96.825  106.617 79.310  1.00 187.32 ? 136 GLU B CA  1 
ATOM   4321  C C   . GLU B 2 136 ? 98.213  107.225 79.095  1.00 151.24 ? 136 GLU B C   1 
ATOM   4322  O O   . GLU B 2 136 ? 99.208  106.591 79.422  1.00 173.06 ? 136 GLU B O   1 
ATOM   4323  C CB  . GLU B 2 136 ? 96.478  105.638 78.187  1.00 152.06 ? 136 GLU B CB  1 
ATOM   4324  C CG  . GLU B 2 136 ? 95.315  104.763 78.576  1.00 222.36 ? 136 GLU B CG  1 
ATOM   4325  C CD  . GLU B 2 136 ? 95.042  103.567 77.682  1.00 306.93 ? 136 GLU B CD  1 
ATOM   4326  O OE1 . GLU B 2 136 ? 95.155  103.715 76.460  1.00 380.80 ? 136 GLU B OE1 1 
ATOM   4327  O OE2 . GLU B 2 136 ? 94.684  102.489 78.213  1.00 325.67 ? 136 GLU B OE2 1 
ATOM   4328  N N   . LEU B 2 137 ? 98.270  108.429 78.533  1.00 159.67 ? 137 LEU B N   1 
ATOM   4329  C CA  . LEU B 2 137 ? 99.504  109.154 78.305  1.00 166.82 ? 137 LEU B CA  1 
ATOM   4330  C C   . LEU B 2 137 ? 100.033 109.666 79.636  1.00 166.88 ? 137 LEU B C   1 
ATOM   4331  O O   . LEU B 2 137 ? 101.223 109.564 79.867  1.00 176.41 ? 137 LEU B O   1 
ATOM   4332  C CB  . LEU B 2 137 ? 99.175  110.302 77.352  1.00 255.56 ? 137 LEU B CB  1 
ATOM   4333  C CG  . LEU B 2 137 ? 100.356 111.078 76.787  1.00 319.22 ? 137 LEU B CG  1 
ATOM   4334  C CD1 . LEU B 2 137 ? 100.854 110.462 75.487  1.00 326.75 ? 137 LEU B CD1 1 
ATOM   4335  C CD2 . LEU B 2 137 ? 99.989  112.531 76.545  1.00 376.22 ? 137 LEU B CD2 1 
ATOM   4336  N N   . LEU B 2 138 ? 99.151  110.197 80.497  1.00 186.94 ? 138 LEU B N   1 
ATOM   4337  C CA  . LEU B 2 138 ? 99.565  110.793 81.761  1.00 234.66 ? 138 LEU B CA  1 
ATOM   4338  C C   . LEU B 2 138 ? 99.715  109.769 82.880  1.00 219.48 ? 138 LEU B C   1 
ATOM   4339  O O   . LEU B 2 138 ? 100.640 109.931 83.673  1.00 253.54 ? 138 LEU B O   1 
ATOM   4340  C CB  . LEU B 2 138 ? 98.543  111.831 82.231  1.00 326.66 ? 138 LEU B CB  1 
ATOM   4341  C CG  . LEU B 2 138 ? 98.525  113.182 81.522  1.00 423.75 ? 138 LEU B CG  1 
ATOM   4342  C CD1 . LEU B 2 138 ? 97.768  114.190 82.380  1.00 472.52 ? 138 LEU B CD1 1 
ATOM   4343  C CD2 . LEU B 2 138 ? 99.918  113.715 81.207  1.00 439.88 ? 138 LEU B CD2 1 
ATOM   4344  N N   . ILE B 2 139 ? 98.826  108.764 82.990  1.00 169.61 ? 139 ILE B N   1 
ATOM   4345  C CA  . ILE B 2 139 ? 98.799  107.997 84.236  1.00 182.00 ? 139 ILE B CA  1 
ATOM   4346  C C   . ILE B 2 139 ? 98.800  106.489 83.996  1.00 193.38 ? 139 ILE B C   1 
ATOM   4347  O O   . ILE B 2 139 ? 99.625  105.838 84.625  1.00 225.44 ? 139 ILE B O   1 
ATOM   4348  C CB  . ILE B 2 139 ? 97.691  108.477 85.216  1.00 227.54 ? 139 ILE B CB  1 
ATOM   4349  C CG1 . ILE B 2 139 ? 97.812  107.783 86.581  1.00 260.89 ? 139 ILE B CG1 1 
ATOM   4350  C CG2 . ILE B 2 139 ? 96.289  108.313 84.663  1.00 239.93 ? 139 ILE B CG2 1 
ATOM   4351  C CD1 . ILE B 2 139 ? 96.946  108.375 87.679  1.00 263.30 ? 139 ILE B CD1 1 
ATOM   4352  N N   . ILE B 2 140 ? 97.953  105.913 83.144  1.00 154.33 ? 140 ILE B N   1 
ATOM   4353  C CA  . ILE B 2 140 ? 97.810  104.457 83.178  1.00 157.75 ? 140 ILE B CA  1 
ATOM   4354  C C   . ILE B 2 140 ? 99.107  103.732 82.786  1.00 159.39 ? 140 ILE B C   1 
ATOM   4355  O O   . ILE B 2 140 ? 99.595  102.890 83.539  1.00 191.45 ? 140 ILE B O   1 
ATOM   4356  C CB  . ILE B 2 140 ? 96.640  103.964 82.313  1.00 172.57 ? 140 ILE B CB  1 
ATOM   4357  C CG1 . ILE B 2 140 ? 95.358  104.735 82.604  1.00 195.51 ? 140 ILE B CG1 1 
ATOM   4358  C CG2 . ILE B 2 140 ? 96.409  102.461 82.479  1.00 224.43 ? 140 ILE B CG2 1 
ATOM   4359  C CD1 . ILE B 2 140 ? 94.895  104.653 84.034  1.00 279.93 ? 140 ILE B CD1 1 
ATOM   4360  N N   . ARG B 2 141 ? 99.671  104.010 81.615  1.00 117.45 ? 141 ARG B N   1 
ATOM   4361  C CA  . ARG B 2 141 ? 100.763 103.176 81.139  1.00 148.01 ? 141 ARG B CA  1 
ATOM   4362  C C   . ARG B 2 141 ? 102.090 103.608 81.759  1.00 172.36 ? 141 ARG B C   1 
ATOM   4363  O O   . ARG B 2 141 ? 102.954 102.754 81.959  1.00 222.63 ? 141 ARG B O   1 
ATOM   4364  C CB  . ARG B 2 141 ? 100.819 103.159 79.613  1.00 167.13 ? 141 ARG B CB  1 
ATOM   4365  C CG  . ARG B 2 141 ? 99.484  102.835 78.951  1.00 186.95 ? 141 ARG B CG  1 
ATOM   4366  C CD  . ARG B 2 141 ? 98.870  101.512 79.344  1.00 165.72 ? 141 ARG B CD  1 
ATOM   4367  N NE  . ARG B 2 141 ? 99.851  100.485 79.023  1.00 195.45 ? 141 ARG B NE  1 
ATOM   4368  C CZ  . ARG B 2 141 ? 99.927  99.775  77.894  1.00 222.73 ? 141 ARG B CZ  1 
ATOM   4369  N NH1 . ARG B 2 141 ? 100.850 98.831  77.798  1.00 256.82 ? 141 ARG B NH1 1 
ATOM   4370  N NH2 . ARG B 2 141 ? 99.114  99.984  76.868  1.00 195.82 ? 141 ARG B NH2 1 
ATOM   4371  N N   . PRO B 2 142 ? 102.342 104.899 82.067  1.00 141.43 ? 142 PRO B N   1 
ATOM   4372  C CA  . PRO B 2 142 ? 103.459 105.249 82.932  1.00 152.55 ? 142 PRO B CA  1 
ATOM   4373  C C   . PRO B 2 142 ? 103.402 104.594 84.301  1.00 153.09 ? 142 PRO B C   1 
ATOM   4374  O O   . PRO B 2 142 ? 104.348 103.898 84.669  1.00 179.61 ? 142 PRO B O   1 
ATOM   4375  C CB  . PRO B 2 142 ? 103.354 106.766 83.054  1.00 185.30 ? 142 PRO B CB  1 
ATOM   4376  C CG  . PRO B 2 142 ? 102.711 107.158 81.744  1.00 241.35 ? 142 PRO B CG  1 
ATOM   4377  C CD  . PRO B 2 142 ? 101.659 106.091 81.561  1.00 168.44 ? 142 PRO B CD  1 
ATOM   4378  N N   . SER B 2 143 ? 102.317 104.800 85.044  1.00 141.92 ? 143 SER B N   1 
ATOM   4379  C CA  . SER B 2 143 ? 102.282 104.344 86.416  1.00 142.62 ? 143 SER B CA  1 
ATOM   4380  C C   . SER B 2 143 ? 102.384 102.819 86.493  1.00 132.29 ? 143 SER B C   1 
ATOM   4381  O O   . SER B 2 143 ? 103.145 102.325 87.327  1.00 196.37 ? 143 SER B O   1 
ATOM   4382  C CB  . SER B 2 143 ? 101.073 104.879 87.113  1.00 161.18 ? 143 SER B CB  1 
ATOM   4383  O OG  . SER B 2 143 ? 99.886  104.221 86.696  1.00 188.10 ? 143 SER B OG  1 
ATOM   4384  N N   . SER B 2 144 ? 101.649 102.069 85.661  1.00 127.16 ? 144 SER B N   1 
ATOM   4385  C CA  . SER B 2 144 ? 101.749 100.612 85.702  1.00 161.71 ? 144 SER B CA  1 
ATOM   4386  C C   . SER B 2 144 ? 103.150 100.080 85.363  1.00 138.31 ? 144 SER B C   1 
ATOM   4387  O O   . SER B 2 144 ? 103.601 99.089  85.964  1.00 133.16 ? 144 SER B O   1 
ATOM   4388  C CB  . SER B 2 144 ? 100.718 99.977  84.843  1.00 183.46 ? 144 SER B CB  1 
ATOM   4389  O OG  . SER B 2 144 ? 100.902 100.306 83.490  1.00 205.26 ? 144 SER B OG  1 
ATOM   4390  N N   . GLN B 2 145 ? 103.843 100.732 84.428  1.00 126.33 ? 145 GLN B N   1 
ATOM   4391  C CA  . GLN B 2 145 ? 105.226 100.371 84.151  1.00 149.33 ? 145 GLN B CA  1 
ATOM   4392  C C   . GLN B 2 145 ? 106.098 100.627 85.368  1.00 109.31 ? 145 GLN B C   1 
ATOM   4393  O O   . GLN B 2 145 ? 106.936 99.796  85.693  1.00 94.86  ? 145 GLN B O   1 
ATOM   4394  C CB  . GLN B 2 145 ? 105.772 101.091 82.916  1.00 163.82 ? 145 GLN B CB  1 
ATOM   4395  C CG  . GLN B 2 145 ? 105.262 100.418 81.663  1.00 205.18 ? 145 GLN B CG  1 
ATOM   4396  C CD  . GLN B 2 145 ? 105.281 101.199 80.376  1.00 226.63 ? 145 GLN B CD  1 
ATOM   4397  O OE1 . GLN B 2 145 ? 104.722 100.750 79.378  1.00 313.24 ? 145 GLN B OE1 1 
ATOM   4398  N NE2 . GLN B 2 145 ? 105.906 102.360 80.370  1.00 214.85 ? 145 GLN B NE2 1 
ATOM   4399  N N   . TYR B 2 146 ? 105.923 101.758 86.042  1.00 125.91 ? 146 TYR B N   1 
ATOM   4400  C CA  . TYR B 2 146 ? 106.793 102.068 87.173  1.00 141.19 ? 146 TYR B CA  1 
ATOM   4401  C C   . TYR B 2 146 ? 106.487 101.194 88.372  1.00 103.47 ? 146 TYR B C   1 
ATOM   4402  O O   . TYR B 2 146 ? 107.398 100.859 89.120  1.00 105.97 ? 146 TYR B O   1 
ATOM   4403  C CB  . TYR B 2 146 ? 106.689 103.518 87.640  1.00 166.16 ? 146 TYR B CB  1 
ATOM   4404  C CG  . TYR B 2 146 ? 107.873 103.841 88.524  1.00 143.01 ? 146 TYR B CG  1 
ATOM   4405  C CD1 . TYR B 2 146 ? 109.179 103.735 88.027  1.00 193.18 ? 146 TYR B CD1 1 
ATOM   4406  C CD2 . TYR B 2 146 ? 107.683 104.245 89.826  1.00 154.32 ? 146 TYR B CD2 1 
ATOM   4407  C CE1 . TYR B 2 146 ? 110.275 104.019 88.812  1.00 206.38 ? 146 TYR B CE1 1 
ATOM   4408  C CE2 . TYR B 2 146 ? 108.777 104.546 90.623  1.00 213.63 ? 146 TYR B CE2 1 
ATOM   4409  C CZ  . TYR B 2 146 ? 110.064 104.427 90.112  1.00 212.86 ? 146 TYR B CZ  1 
ATOM   4410  O OH  . TYR B 2 146 ? 111.144 104.702 90.873  1.00 226.02 ? 146 TYR B OH  1 
ATOM   4411  N N   . ILE B 2 147 ? 105.217 100.833 88.512  1.00 112.86 ? 147 ILE B N   1 
ATOM   4412  C CA  . ILE B 2 147 ? 104.799 99.865  89.502  1.00 126.16 ? 147 ILE B CA  1 
ATOM   4413  C C   . ILE B 2 147 ? 105.474 98.517  89.268  1.00 120.43 ? 147 ILE B C   1 
ATOM   4414  O O   . ILE B 2 147 ? 106.104 98.047  90.230  1.00 158.52 ? 147 ILE B O   1 
ATOM   4415  C CB  . ILE B 2 147 ? 103.264 99.846  89.543  1.00 152.41 ? 147 ILE B CB  1 
ATOM   4416  C CG1 . ILE B 2 147 ? 102.842 101.063 90.395  1.00 175.66 ? 147 ILE B CG1 1 
ATOM   4417  C CG2 . ILE B 2 147 ? 102.707 98.484  89.992  1.00 137.40 ? 147 ILE B CG2 1 
ATOM   4418  C CD1 . ILE B 2 147 ? 101.372 101.497 90.307  1.00 185.68 ? 147 ILE B CD1 1 
ATOM   4419  N N   . VAL B 2 148 ? 105.397 97.905  88.072  1.00 76.56  ? 148 VAL B N   1 
ATOM   4420  C CA  . VAL B 2 148 ? 106.094 96.620  87.977  1.00 112.56 ? 148 VAL B CA  1 
ATOM   4421  C C   . VAL B 2 148 ? 107.618 96.783  87.949  1.00 109.58 ? 148 VAL B C   1 
ATOM   4422  O O   . VAL B 2 148 ? 108.324 95.816  88.212  1.00 135.07 ? 148 VAL B O   1 
ATOM   4423  C CB  . VAL B 2 148 ? 105.633 95.710  86.843  1.00 115.41 ? 148 VAL B CB  1 
ATOM   4424  C CG1 . VAL B 2 148 ? 104.150 95.494  87.003  1.00 202.15 ? 148 VAL B CG1 1 
ATOM   4425  C CG2 . VAL B 2 148 ? 105.923 96.275  85.485  1.00 162.07 ? 148 VAL B CG2 1 
ATOM   4426  N N   . ALA B 2 149 ? 108.148 97.969  87.669  1.00 85.14  ? 149 ALA B N   1 
ATOM   4427  C CA  . ALA B 2 149 ? 109.587 98.137  87.723  1.00 98.16  ? 149 ALA B CA  1 
ATOM   4428  C C   . ALA B 2 149 ? 110.057 98.180  89.156  1.00 126.58 ? 149 ALA B C   1 
ATOM   4429  O O   . ALA B 2 149 ? 111.137 97.659  89.430  1.00 140.87 ? 149 ALA B O   1 
ATOM   4430  C CB  . ALA B 2 149 ? 109.993 99.406  87.014  1.00 125.57 ? 149 ALA B CB  1 
ATOM   4431  N N   . LEU B 2 150 ? 109.282 98.827  90.056  1.00 137.75 ? 150 LEU B N   1 
ATOM   4432  C CA  . LEU B 2 150 ? 109.700 98.910  91.451  1.00 114.51 ? 150 LEU B CA  1 
ATOM   4433  C C   . LEU B 2 150 ? 109.661 97.541  92.062  1.00 110.12 ? 150 LEU B C   1 
ATOM   4434  O O   . LEU B 2 150 ? 110.505 97.266  92.910  1.00 144.63 ? 150 LEU B O   1 
ATOM   4435  C CB  . LEU B 2 150 ? 108.820 99.840  92.269  1.00 137.70 ? 150 LEU B CB  1 
ATOM   4436  C CG  . LEU B 2 150 ? 109.459 101.198 92.519  1.00 201.02 ? 150 LEU B CG  1 
ATOM   4437  C CD1 . LEU B 2 150 ? 108.429 102.180 93.062  1.00 284.82 ? 150 LEU B CD1 1 
ATOM   4438  C CD2 . LEU B 2 150 ? 110.634 101.092 93.473  1.00 198.77 ? 150 LEU B CD2 1 
ATOM   4439  N N   . VAL B 2 151 ? 108.691 96.731  91.641  1.00 104.02 ? 151 VAL B N   1 
ATOM   4440  C CA  . VAL B 2 151 ? 108.613 95.372  92.142  1.00 127.82 ? 151 VAL B CA  1 
ATOM   4441  C C   . VAL B 2 151 ? 109.808 94.560  91.641  1.00 119.03 ? 151 VAL B C   1 
ATOM   4442  O O   . VAL B 2 151 ? 110.354 93.728  92.379  1.00 117.10 ? 151 VAL B O   1 
ATOM   4443  C CB  . VAL B 2 151 ? 107.252 94.725  91.825  1.00 123.02 ? 151 VAL B CB  1 
ATOM   4444  C CG1 . VAL B 2 151 ? 107.192 93.267  92.291  1.00 141.25 ? 151 VAL B CG1 1 
ATOM   4445  C CG2 . VAL B 2 151 ? 106.128 95.533  92.475  1.00 152.35 ? 151 VAL B CG2 1 
ATOM   4446  N N   . PHE B 2 152 ? 110.219 94.775  90.396  1.00 122.86 ? 152 PHE B N   1 
ATOM   4447  C CA  . PHE B 2 152 ? 111.392 94.093  89.907  1.00 125.75 ? 152 PHE B CA  1 
ATOM   4448  C C   . PHE B 2 152 ? 112.553 94.412  90.819  1.00 102.30 ? 152 PHE B C   1 
ATOM   4449  O O   . PHE B 2 152 ? 113.238 93.510  91.278  1.00 138.62 ? 152 PHE B O   1 
ATOM   4450  C CB  . PHE B 2 152 ? 111.707 94.517  88.479  1.00 131.26 ? 152 PHE B CB  1 
ATOM   4451  C CG  . PHE B 2 152 ? 113.128 94.273  88.074  1.00 121.70 ? 152 PHE B CG  1 
ATOM   4452  C CD1 . PHE B 2 152 ? 113.577 92.997  87.788  1.00 117.78 ? 152 PHE B CD1 1 
ATOM   4453  C CD2 . PHE B 2 152 ? 113.998 95.339  87.982  1.00 140.67 ? 152 PHE B CD2 1 
ATOM   4454  C CE1 . PHE B 2 152 ? 114.884 92.778  87.416  1.00 157.82 ? 152 PHE B CE1 1 
ATOM   4455  C CE2 . PHE B 2 152 ? 115.309 95.125  87.613  1.00 163.18 ? 152 PHE B CE2 1 
ATOM   4456  C CZ  . PHE B 2 152 ? 115.741 93.850  87.322  1.00 176.51 ? 152 PHE B CZ  1 
ATOM   4457  N N   . ALA B 2 153 ? 112.781 95.696  91.067  1.00 106.06 ? 153 ALA B N   1 
ATOM   4458  C CA  . ALA B 2 153 ? 113.957 96.101  91.824  1.00 150.18 ? 153 ALA B CA  1 
ATOM   4459  C C   . ALA B 2 153 ? 113.912 95.571  93.251  1.00 134.57 ? 153 ALA B C   1 
ATOM   4460  O O   . ALA B 2 153 ? 114.896 95.023  93.759  1.00 120.51 ? 153 ALA B O   1 
ATOM   4461  C CB  . ALA B 2 153 ? 114.054 97.587  91.804  1.00 173.35 ? 153 ALA B CB  1 
ATOM   4462  N N   . THR B 2 154 ? 112.755 95.723  93.880  1.00 121.11 ? 154 THR B N   1 
ATOM   4463  C CA  . THR B 2 154 ? 112.563 95.242  95.233  1.00 106.39 ? 154 THR B CA  1 
ATOM   4464  C C   . THR B 2 154 ? 112.860 93.749  95.341  1.00 100.47 ? 154 THR B C   1 
ATOM   4465  O O   . THR B 2 154 ? 113.676 93.370  96.189  1.00 116.07 ? 154 THR B O   1 
ATOM   4466  C CB  . THR B 2 154 ? 111.154 95.610  95.699  1.00 125.67 ? 154 THR B CB  1 
ATOM   4467  O OG1 . THR B 2 154 ? 111.149 97.041  95.788  1.00 123.25 ? 154 THR B OG1 1 
ATOM   4468  C CG2 . THR B 2 154 ? 110.739 94.978  97.013  1.00 195.80 ? 154 THR B CG2 1 
ATOM   4469  N N   . TYR B 2 155 ? 112.208 92.912  94.525  1.00 82.07  ? 155 TYR B N   1 
ATOM   4470  C CA  . TYR B 2 155 ? 112.329 91.480  94.748  1.00 130.99 ? 155 TYR B CA  1 
ATOM   4471  C C   . TYR B 2 155 ? 113.700 90.962  94.289  1.00 117.51 ? 155 TYR B C   1 
ATOM   4472  O O   . TYR B 2 155 ? 114.179 89.935  94.781  1.00 128.22 ? 155 TYR B O   1 
ATOM   4473  C CB  . TYR B 2 155 ? 111.204 90.679  94.102  1.00 125.71 ? 155 TYR B CB  1 
ATOM   4474  C CG  . TYR B 2 155 ? 109.951 90.699  94.937  1.00 136.90 ? 155 TYR B CG  1 
ATOM   4475  C CD1 . TYR B 2 155 ? 109.245 91.891  95.090  1.00 147.11 ? 155 TYR B CD1 1 
ATOM   4476  C CD2 . TYR B 2 155 ? 109.483 89.550  95.552  1.00 141.18 ? 155 TYR B CD2 1 
ATOM   4477  C CE1 . TYR B 2 155 ? 108.079 91.957  95.832  1.00 153.20 ? 155 TYR B CE1 1 
ATOM   4478  C CE2 . TYR B 2 155 ? 108.309 89.609  96.292  1.00 208.61 ? 155 TYR B CE2 1 
ATOM   4479  C CZ  . TYR B 2 155 ? 107.609 90.806  96.435  1.00 200.90 ? 155 TYR B CZ  1 
ATOM   4480  O OH  . TYR B 2 155 ? 106.457 90.877  97.172  1.00 234.49 ? 155 TYR B OH  1 
ATOM   4481  N N   . LEU B 2 156 ? 114.326 91.652  93.349  1.00 114.02 ? 156 LEU B N   1 
ATOM   4482  C CA  . LEU B 2 156 ? 115.609 91.208  92.855  1.00 139.97 ? 156 LEU B CA  1 
ATOM   4483  C C   . LEU B 2 156 ? 116.652 91.481  93.920  1.00 132.27 ? 156 LEU B C   1 
ATOM   4484  O O   . LEU B 2 156 ? 117.570 90.684  94.071  1.00 171.10 ? 156 LEU B O   1 
ATOM   4485  C CB  . LEU B 2 156 ? 115.933 91.972  91.572  1.00 167.36 ? 156 LEU B CB  1 
ATOM   4486  C CG  . LEU B 2 156 ? 117.340 91.756  91.056  1.00 180.73 ? 156 LEU B CG  1 
ATOM   4487  C CD1 . LEU B 2 156 ? 117.489 90.317  90.572  1.00 211.87 ? 156 LEU B CD1 1 
ATOM   4488  C CD2 . LEU B 2 156 ? 117.633 92.781  89.996  1.00 192.17 ? 156 LEU B CD2 1 
ATOM   4489  N N   . LEU B 2 157 ? 116.525 92.610  94.620  1.00 116.87 ? 157 LEU B N   1 
ATOM   4490  C CA  . LEU B 2 157 ? 117.504 92.955  95.633  1.00 134.43 ? 157 LEU B CA  1 
ATOM   4491  C C   . LEU B 2 157 ? 117.241 92.269  96.970  1.00 142.33 ? 157 LEU B C   1 
ATOM   4492  O O   . LEU B 2 157 ? 118.159 92.205  97.767  1.00 129.51 ? 157 LEU B O   1 
ATOM   4493  C CB  . LEU B 2 157 ? 117.450 94.461  95.809  1.00 138.71 ? 157 LEU B CB  1 
ATOM   4494  C CG  . LEU B 2 157 ? 118.065 95.272  94.690  1.00 128.09 ? 157 LEU B CG  1 
ATOM   4495  C CD1 . LEU B 2 157 ? 117.812 96.775  94.935  1.00 111.24 ? 157 LEU B CD1 1 
ATOM   4496  C CD2 . LEU B 2 157 ? 119.547 94.943  94.589  1.00 122.20 ? 157 LEU B CD2 1 
ATOM   4497  N N   . LYS B 2 158 ? 116.030 91.761  97.219  1.00 134.06 ? 158 LYS B N   1 
ATOM   4498  C CA  . LYS B 2 158 ? 115.645 91.197  98.510  1.00 125.50 ? 158 LYS B CA  1 
ATOM   4499  C C   . LYS B 2 158 ? 116.613 90.156  99.100  1.00 115.45 ? 158 LYS B C   1 
ATOM   4500  O O   . LYS B 2 158 ? 116.862 90.203  100.290 1.00 203.36 ? 158 LYS B O   1 
ATOM   4501  C CB  . LYS B 2 158 ? 114.267 90.555  98.433  1.00 140.24 ? 158 LYS B CB  1 
ATOM   4502  C CG  . LYS B 2 158 ? 113.560 90.482  99.779  1.00 142.14 ? 158 LYS B CG  1 
ATOM   4503  C CD  . LYS B 2 158 ? 112.955 91.804  100.193 1.00 171.59 ? 158 LYS B CD  1 
ATOM   4504  C CE  . LYS B 2 158 ? 111.665 91.689  100.991 1.00 234.50 ? 158 LYS B CE  1 
ATOM   4505  N NZ  . LYS B 2 158 ? 110.682 92.756  100.650 1.00 248.24 ? 158 LYS B NZ  1 
ATOM   4506  N N   . PRO B 2 159 ? 117.246 89.203  98.399  1.00 100.87 ? 159 PRO B N   1 
ATOM   4507  C CA  . PRO B 2 159 ? 118.292 88.379  99.018  1.00 137.85 ? 159 PRO B CA  1 
ATOM   4508  C C   . PRO B 2 159 ? 119.613 89.075  99.455  1.00 144.01 ? 159 PRO B C   1 
ATOM   4509  O O   . PRO B 2 159 ? 120.465 88.438  100.094 1.00 146.85 ? 159 PRO B O   1 
ATOM   4510  C CB  . PRO B 2 159 ? 118.567 87.319  97.938  1.00 186.34 ? 159 PRO B CB  1 
ATOM   4511  C CG  . PRO B 2 159 ? 118.293 88.074  96.684  1.00 199.89 ? 159 PRO B CG  1 
ATOM   4512  C CD  . PRO B 2 159 ? 117.038 88.857  97.010  1.00 147.09 ? 159 PRO B CD  1 
ATOM   4513  N N   . LEU B 2 160 ? 119.819 90.375  99.171  1.00 117.89 ? 160 LEU B N   1 
ATOM   4514  C CA  . LEU B 2 160 ? 120.867 91.154  99.865  1.00 165.30 ? 160 LEU B CA  1 
ATOM   4515  C C   . LEU B 2 160 ? 120.418 91.793  101.205 1.00 153.93 ? 160 LEU B C   1 
ATOM   4516  O O   . LEU B 2 160 ? 121.227 92.313  101.997 1.00 109.67 ? 160 LEU B O   1 
ATOM   4517  C CB  . LEU B 2 160 ? 121.337 92.295  98.961  1.00 135.27 ? 160 LEU B CB  1 
ATOM   4518  C CG  . LEU B 2 160 ? 121.711 91.961  97.533  1.00 193.91 ? 160 LEU B CG  1 
ATOM   4519  C CD1 . LEU B 2 160 ? 122.255 93.220  96.912  1.00 193.22 ? 160 LEU B CD1 1 
ATOM   4520  C CD2 . LEU B 2 160 ? 122.738 90.838  97.445  1.00 285.49 ? 160 LEU B CD2 1 
ATOM   4521  N N   . PHE B 2 161 ? 119.100 91.777  101.448 1.00 123.45 ? 161 PHE B N   1 
ATOM   4522  C CA  . PHE B 2 161 ? 118.436 92.475  102.528 1.00 109.72 ? 161 PHE B CA  1 
ATOM   4523  C C   . PHE B 2 161 ? 117.268 91.626  103.053 1.00 127.18 ? 161 PHE B C   1 
ATOM   4524  O O   . PHE B 2 161 ? 116.098 92.056  103.095 1.00 137.25 ? 161 PHE B O   1 
ATOM   4525  C CB  . PHE B 2 161 ? 117.948 93.855  102.028 1.00 129.40 ? 161 PHE B CB  1 
ATOM   4526  C CG  . PHE B 2 161 ? 119.047 94.811  101.673 1.00 101.68 ? 161 PHE B CG  1 
ATOM   4527  C CD1 . PHE B 2 161 ? 119.667 95.564  102.617 1.00 155.09 ? 161 PHE B CD1 1 
ATOM   4528  C CD2 . PHE B 2 161 ? 119.492 94.910  100.405 1.00 120.38 ? 161 PHE B CD2 1 
ATOM   4529  C CE1 . PHE B 2 161 ? 120.700 96.408  102.293 1.00 187.87 ? 161 PHE B CE1 1 
ATOM   4530  C CE2 . PHE B 2 161 ? 120.523 95.746  100.066 1.00 142.32 ? 161 PHE B CE2 1 
ATOM   4531  C CZ  . PHE B 2 161 ? 121.125 96.498  101.009 1.00 143.10 ? 161 PHE B CZ  1 
ATOM   4532  N N   . PRO B 2 162 ? 117.507 90.377  103.500 1.00 129.03 ? 162 PRO B N   1 
ATOM   4533  C CA  . PRO B 2 162 ? 116.409 89.597  104.081 1.00 152.04 ? 162 PRO B CA  1 
ATOM   4534  C C   . PRO B 2 162 ? 116.169 90.165  105.483 1.00 199.06 ? 162 PRO B C   1 
ATOM   4535  O O   . PRO B 2 162 ? 117.129 90.467  106.204 1.00 180.31 ? 162 PRO B O   1 
ATOM   4536  C CB  . PRO B 2 162 ? 116.977 88.182  104.096 1.00 185.49 ? 162 PRO B CB  1 
ATOM   4537  C CG  . PRO B 2 162 ? 118.499 88.405  104.261 1.00 202.48 ? 162 PRO B CG  1 
ATOM   4538  C CD  . PRO B 2 162 ? 118.811 89.683  103.496 1.00 138.48 ? 162 PRO B CD  1 
ATOM   4539  N N   . THR B 2 163 ? 114.897 90.336  105.857 1.00 196.83 ? 163 THR B N   1 
ATOM   4540  C CA  . THR B 2 163 ? 114.484 90.767  107.197 1.00 193.06 ? 163 THR B CA  1 
ATOM   4541  C C   . THR B 2 163 ? 114.869 92.220  107.488 1.00 135.27 ? 163 THR B C   1 
ATOM   4542  O O   . THR B 2 163 ? 114.968 92.593  108.657 1.00 171.85 ? 163 THR B O   1 
ATOM   4543  C CB  . THR B 2 163 ? 114.945 89.808  108.330 1.00 257.87 ? 163 THR B CB  1 
ATOM   4544  O OG1 . THR B 2 163 ? 116.365 89.828  108.555 1.00 165.08 ? 163 THR B OG1 1 
ATOM   4545  C CG2 . THR B 2 163 ? 114.479 88.382  108.086 1.00 368.38 ? 163 THR B CG2 1 
ATOM   4546  N N   . CYS B 2 164 ? 115.046 93.051  106.444 1.00 128.00 ? 164 CYS B N   1 
ATOM   4547  C CA  . CYS B 2 164 ? 114.970 94.493  106.603 1.00 148.29 ? 164 CYS B CA  1 
ATOM   4548  C C   . CYS B 2 164 ? 114.503 95.160  105.322 1.00 129.07 ? 164 CYS B C   1 
ATOM   4549  O O   . CYS B 2 164 ? 114.508 94.533  104.279 1.00 190.30 ? 164 CYS B O   1 
ATOM   4550  C CB  . CYS B 2 164 ? 116.293 95.106  107.047 1.00 178.48 ? 164 CYS B CB  1 
ATOM   4551  S SG  . CYS B 2 164 ? 117.759 94.571  106.146 1.00 118.64 ? 164 CYS B SG  1 
ATOM   4552  N N   . PRO B 2 165 ? 114.038 96.429  105.355 1.00 153.07 ? 165 PRO B N   1 
ATOM   4553  C CA  . PRO B 2 165 ? 113.748 97.164  104.139 1.00 167.45 ? 165 PRO B CA  1 
ATOM   4554  C C   . PRO B 2 165 ? 114.962 97.233  103.219 1.00 207.42 ? 165 PRO B C   1 
ATOM   4555  O O   . PRO B 2 165 ? 116.086 97.499  103.656 1.00 141.97 ? 165 PRO B O   1 
ATOM   4556  C CB  . PRO B 2 165 ? 113.354 98.551  104.638 1.00 229.58 ? 165 PRO B CB  1 
ATOM   4557  C CG  . PRO B 2 165 ? 112.742 98.252  105.962 1.00 269.09 ? 165 PRO B CG  1 
ATOM   4558  C CD  . PRO B 2 165 ? 113.709 97.240  106.533 1.00 266.52 ? 165 PRO B CD  1 
ATOM   4559  N N   . VAL B 2 166 ? 114.672 96.972  101.937 1.00 220.78 ? 166 VAL B N   1 
ATOM   4560  C CA  . VAL B 2 166 ? 115.614 97.096  100.845 1.00 167.54 ? 166 VAL B CA  1 
ATOM   4561  C C   . VAL B 2 166 ? 115.773 98.587  100.535 1.00 185.20 ? 166 VAL B C   1 
ATOM   4562  O O   . VAL B 2 166 ? 114.744 99.299  100.461 1.00 120.82 ? 166 VAL B O   1 
ATOM   4563  C CB  . VAL B 2 166 ? 115.113 96.270  99.657  1.00 156.76 ? 166 VAL B CB  1 
ATOM   4564  C CG1 . VAL B 2 166 ? 113.824 96.838  99.071  1.00 205.68 ? 166 VAL B CG1 1 
ATOM   4565  C CG2 . VAL B 2 166 ? 116.164 96.173  98.599  1.00 144.66 ? 166 VAL B CG2 1 
ATOM   4566  N N   . PRO B 2 167 ? 117.030 99.108  100.371 1.00 170.61 ? 167 PRO B N   1 
ATOM   4567  C CA  . PRO B 2 167 ? 117.272 100.569 100.445 1.00 154.55 ? 167 PRO B CA  1 
ATOM   4568  C C   . PRO B 2 167 ? 116.509 101.336 99.373  1.00 143.51 ? 167 PRO B C   1 
ATOM   4569  O O   . PRO B 2 167 ? 116.713 101.055 98.189  1.00 228.94 ? 167 PRO B O   1 
ATOM   4570  C CB  . PRO B 2 167 ? 118.779 100.710 100.259 1.00 149.08 ? 167 PRO B CB  1 
ATOM   4571  C CG  . PRO B 2 167 ? 119.340 99.304  100.542 1.00 118.77 ? 167 PRO B CG  1 
ATOM   4572  C CD  . PRO B 2 167 ? 118.261 98.322  100.162 1.00 105.08 ? 167 PRO B CD  1 
ATOM   4573  N N   . GLU B 2 168 ? 115.625 102.265 99.790  1.00 201.80 ? 168 GLU B N   1 
ATOM   4574  C CA  . GLU B 2 168 ? 114.609 102.865 98.915  1.00 208.06 ? 168 GLU B CA  1 
ATOM   4575  C C   . GLU B 2 168 ? 115.234 103.436 97.639  1.00 191.95 ? 168 GLU B C   1 
ATOM   4576  O O   . GLU B 2 168 ? 114.694 103.229 96.553  1.00 133.42 ? 168 GLU B O   1 
ATOM   4577  C CB  . GLU B 2 168 ? 113.826 104.001 99.584  1.00 217.91 ? 168 GLU B CB  1 
ATOM   4578  C CG  . GLU B 2 168 ? 112.995 103.564 100.766 1.00 340.33 ? 168 GLU B CG  1 
ATOM   4579  C CD  . GLU B 2 168 ? 112.185 104.689 101.383 1.00 466.59 ? 168 GLU B CD  1 
ATOM   4580  O OE1 . GLU B 2 168 ? 111.325 105.250 100.673 1.00 545.52 ? 168 GLU B OE1 1 
ATOM   4581  O OE2 . GLU B 2 168 ? 112.414 105.003 102.569 1.00 538.25 ? 168 GLU B OE2 1 
ATOM   4582  N N   . GLU B 2 169 ? 116.367 104.155 97.788  1.00 190.02 ? 169 GLU B N   1 
ATOM   4583  C CA  . GLU B 2 169 ? 117.021 104.826 96.678  1.00 190.17 ? 169 GLU B CA  1 
ATOM   4584  C C   . GLU B 2 169 ? 117.635 103.811 95.709  1.00 131.93 ? 169 GLU B C   1 
ATOM   4585  O O   . GLU B 2 169 ? 117.593 104.055 94.505  1.00 155.55 ? 169 GLU B O   1 
ATOM   4586  C CB  . GLU B 2 169 ? 117.990 105.870 97.234  1.00 258.73 ? 169 GLU B CB  1 
ATOM   4587  C CG  . GLU B 2 169 ? 117.253 107.076 97.843  1.00 325.83 ? 169 GLU B CG  1 
ATOM   4588  C CD  . GLU B 2 169 ? 116.234 107.776 96.943  1.00 369.61 ? 169 GLU B CD  1 
ATOM   4589  O OE1 . GLU B 2 169 ? 116.662 108.287 95.887  1.00 384.70 ? 169 GLU B OE1 1 
ATOM   4590  O OE2 . GLU B 2 169 ? 115.023 107.808 97.280  1.00 361.94 ? 169 GLU B OE2 1 
ATOM   4591  N N   . ALA B 2 170 ? 118.190 102.692 96.187  1.00 124.42 ? 170 ALA B N   1 
ATOM   4592  C CA  . ALA B 2 170 ? 118.653 101.626 95.285  1.00 144.51 ? 170 ALA B CA  1 
ATOM   4593  C C   . ALA B 2 170 ? 117.487 100.889 94.583  1.00 120.41 ? 170 ALA B C   1 
ATOM   4594  O O   . ALA B 2 170 ? 117.539 100.483 93.435  1.00 93.33  ? 170 ALA B O   1 
ATOM   4595  C CB  . ALA B 2 170 ? 119.549 100.675 96.026  1.00 110.45 ? 170 ALA B CB  1 
ATOM   4596  N N   . ALA B 2 171 ? 116.381 100.724 95.259  1.00 121.43 ? 171 ALA B N   1 
ATOM   4597  C CA  . ALA B 2 171 ? 115.213 100.188 94.609  1.00 131.19 ? 171 ALA B CA  1 
ATOM   4598  C C   . ALA B 2 171 ? 114.655 101.165 93.583  1.00 126.94 ? 171 ALA B C   1 
ATOM   4599  O O   . ALA B 2 171 ? 114.062 100.699 92.623  1.00 175.48 ? 171 ALA B O   1 
ATOM   4600  C CB  . ALA B 2 171 ? 114.173 99.882  95.670  1.00 259.35 ? 171 ALA B CB  1 
ATOM   4601  N N   . LYS B 2 172 ? 114.783 102.495 93.738  1.00 112.70 ? 172 LYS B N   1 
ATOM   4602  C CA  . LYS B 2 172 ? 114.360 103.405 92.676  1.00 133.23 ? 172 LYS B CA  1 
ATOM   4603  C C   . LYS B 2 172 ? 115.361 103.370 91.518  1.00 107.25 ? 172 LYS B C   1 
ATOM   4604  O O   . LYS B 2 172 ? 114.957 103.305 90.366  1.00 99.45  ? 172 LYS B O   1 
ATOM   4605  C CB  . LYS B 2 172 ? 114.156 104.818 93.199  1.00 137.24 ? 172 LYS B CB  1 
ATOM   4606  C CG  . LYS B 2 172 ? 112.861 105.065 93.987  1.00 126.80 ? 172 LYS B CG  1 
ATOM   4607  C CD  . LYS B 2 172 ? 112.815 106.555 94.279  1.00 262.52 ? 172 LYS B CD  1 
ATOM   4608  C CE  . LYS B 2 172 ? 111.826 107.038 95.314  1.00 350.42 ? 172 LYS B CE  1 
ATOM   4609  N NZ  . LYS B 2 172 ? 112.421 106.920 96.668  1.00 418.79 ? 172 LYS B NZ  1 
ATOM   4610  N N   . LEU B 2 173 ? 116.654 103.382 91.792  1.00 112.16 ? 173 LEU B N   1 
ATOM   4611  C CA  . LEU B 2 173 ? 117.607 103.281 90.691  1.00 128.21 ? 173 LEU B CA  1 
ATOM   4612  C C   . LEU B 2 173 ? 117.418 102.012 89.890  1.00 120.14 ? 173 LEU B C   1 
ATOM   4613  O O   . LEU B 2 173 ? 117.414 102.076 88.653  1.00 167.18 ? 173 LEU B O   1 
ATOM   4614  C CB  . LEU B 2 173 ? 119.070 103.238 91.137  1.00 123.44 ? 173 LEU B CB  1 
ATOM   4615  C CG  . LEU B 2 173 ? 119.627 104.561 91.654  1.00 169.43 ? 173 LEU B CG  1 
ATOM   4616  C CD1 . LEU B 2 173 ? 121.151 104.539 91.459  1.00 157.65 ? 173 LEU B CD1 1 
ATOM   4617  C CD2 . LEU B 2 173 ? 118.936 105.833 91.049  1.00 149.13 ? 173 LEU B CD2 1 
ATOM   4618  N N   . VAL B 2 174 ? 117.328 100.873 90.570  1.00 83.45  ? 174 VAL B N   1 
ATOM   4619  C CA  . VAL B 2 174 ? 117.223 99.642  89.816  1.00 105.17 ? 174 VAL B CA  1 
ATOM   4620  C C   . VAL B 2 174 ? 115.866 99.529  89.114  1.00 90.03  ? 174 VAL B C   1 
ATOM   4621  O O   . VAL B 2 174 ? 115.737 98.787  88.149  1.00 127.08 ? 174 VAL B O   1 
ATOM   4622  C CB  . VAL B 2 174 ? 117.629 98.457  90.688  1.00 137.55 ? 174 VAL B CB  1 
ATOM   4623  C CG1 . VAL B 2 174 ? 117.289 97.098  90.054  1.00 147.48 ? 174 VAL B CG1 1 
ATOM   4624  C CG2 . VAL B 2 174 ? 119.129 98.599  90.995  1.00 139.04 ? 174 VAL B CG2 1 
ATOM   4625  N N   . ALA B 2 175 ? 114.856 100.275 89.543  1.00 94.14  ? 175 ALA B N   1 
ATOM   4626  C CA  . ALA B 2 175 ? 113.608 100.344 88.794  1.00 117.83 ? 175 ALA B CA  1 
ATOM   4627  C C   . ALA B 2 175 ? 113.849 101.091 87.501  1.00 132.17 ? 175 ALA B C   1 
ATOM   4628  O O   . ALA B 2 175 ? 113.330 100.681 86.480  1.00 151.49 ? 175 ALA B O   1 
ATOM   4629  C CB  . ALA B 2 175 ? 112.515 101.002 89.619  1.00 175.61 ? 175 ALA B CB  1 
ATOM   4630  N N   . CYS B 2 176 ? 114.635 102.175 87.563  1.00 139.56 ? 176 CYS B N   1 
ATOM   4631  C CA  . CYS B 2 176 ? 114.924 102.988 86.395  1.00 120.44 ? 176 CYS B CA  1 
ATOM   4632  C C   . CYS B 2 176 ? 115.904 102.292 85.462  1.00 115.68 ? 176 CYS B C   1 
ATOM   4633  O O   . CYS B 2 176 ? 115.673 102.365 84.257  1.00 185.68 ? 176 CYS B O   1 
ATOM   4634  C CB  . CYS B 2 176 ? 115.405 104.340 86.862  1.00 133.83 ? 176 CYS B CB  1 
ATOM   4635  S SG  . CYS B 2 176 ? 114.107 105.152 87.841  1.00 225.43 ? 176 CYS B SG  1 
ATOM   4636  N N   . LEU B 2 177 ? 116.951 101.628 85.971  1.00 94.52  ? 177 LEU B N   1 
ATOM   4637  C CA  . LEU B 2 177 ? 117.825 100.805 85.120  1.00 130.49 ? 177 LEU B CA  1 
ATOM   4638  C C   . LEU B 2 177 ? 117.089 99.761  84.264  1.00 145.12 ? 177 LEU B C   1 
ATOM   4639  O O   . LEU B 2 177 ? 117.474 99.527  83.112  1.00 205.07 ? 177 LEU B O   1 
ATOM   4640  C CB  . LEU B 2 177 ? 118.871 100.072 85.959  1.00 135.42 ? 177 LEU B CB  1 
ATOM   4641  C CG  . LEU B 2 177 ? 119.960 101.002 86.503  1.00 174.52 ? 177 LEU B CG  1 
ATOM   4642  C CD1 . LEU B 2 177 ? 120.690 100.336 87.638  1.00 251.25 ? 177 LEU B CD1 1 
ATOM   4643  C CD2 . LEU B 2 177 ? 120.989 101.424 85.469  1.00 128.20 ? 177 LEU B CD2 1 
ATOM   4644  N N   . CYS B 2 178 ? 116.049 99.147  84.824  1.00 150.80 ? 178 CYS B N   1 
ATOM   4645  C CA  . CYS B 2 178 ? 115.184 98.209  84.127  1.00 160.40 ? 178 CYS B CA  1 
ATOM   4646  C C   . CYS B 2 178 ? 114.456 98.885  82.963  1.00 143.00 ? 178 CYS B C   1 
ATOM   4647  O O   . CYS B 2 178 ? 114.570 98.439  81.820  1.00 192.80 ? 178 CYS B O   1 
ATOM   4648  C CB  . CYS B 2 178 ? 114.193 97.642  85.133  1.00 187.06 ? 178 CYS B CB  1 
ATOM   4649  S SG  . CYS B 2 178 ? 112.913 96.610  84.402  1.00 192.87 ? 178 CYS B SG  1 
ATOM   4650  N N   . VAL B 2 179 ? 113.726 99.967  83.249  1.00 103.40 ? 179 VAL B N   1 
ATOM   4651  C CA  . VAL B 2 179 ? 112.988 100.683 82.215  1.00 134.22 ? 179 VAL B CA  1 
ATOM   4652  C C   . VAL B 2 179 ? 113.924 101.184 81.107  1.00 134.16 ? 179 VAL B C   1 
ATOM   4653  O O   . VAL B 2 179 ? 113.610 101.083 79.931  1.00 129.68 ? 179 VAL B O   1 
ATOM   4654  C CB  . VAL B 2 179 ? 112.167 101.838 82.823  1.00 157.66 ? 179 VAL B CB  1 
ATOM   4655  C CG1 . VAL B 2 179 ? 111.646 102.834 81.822  1.00 149.88 ? 179 VAL B CG1 1 
ATOM   4656  C CG2 . VAL B 2 179 ? 110.979 101.321 83.604  1.00 224.98 ? 179 VAL B CG2 1 
ATOM   4657  N N   . LEU B 2 180 ? 115.076 101.728 81.459  1.00 137.12 ? 180 LEU B N   1 
ATOM   4658  C CA  . LEU B 2 180 ? 115.984 102.230 80.446  1.00 115.75 ? 180 LEU B CA  1 
ATOM   4659  C C   . LEU B 2 180 ? 116.540 101.119 79.555  1.00 100.41 ? 180 LEU B C   1 
ATOM   4660  O O   . LEU B 2 180 ? 116.527 101.270 78.332  1.00 154.80 ? 180 LEU B O   1 
ATOM   4661  C CB  . LEU B 2 180 ? 117.155 102.934 81.126  1.00 132.46 ? 180 LEU B CB  1 
ATOM   4662  C CG  . LEU B 2 180 ? 116.868 104.281 81.779  1.00 174.92 ? 180 LEU B CG  1 
ATOM   4663  C CD1 . LEU B 2 180 ? 118.131 104.779 82.468  1.00 207.20 ? 180 LEU B CD1 1 
ATOM   4664  C CD2 . LEU B 2 180 ? 116.379 105.301 80.773  1.00 196.78 ? 180 LEU B CD2 1 
ATOM   4665  N N   . LEU B 2 181 ? 117.045 100.038 80.135  1.00 97.95  ? 181 LEU B N   1 
ATOM   4666  C CA  . LEU B 2 181 ? 117.574 98.963  79.312  1.00 119.78 ? 181 LEU B CA  1 
ATOM   4667  C C   . LEU B 2 181 ? 116.492 98.359  78.394  1.00 129.91 ? 181 LEU B C   1 
ATOM   4668  O O   . LEU B 2 181 ? 116.769 98.091  77.218  1.00 182.49 ? 181 LEU B O   1 
ATOM   4669  C CB  . LEU B 2 181 ? 118.155 97.847  80.171  1.00 133.34 ? 181 LEU B CB  1 
ATOM   4670  C CG  . LEU B 2 181 ? 118.507 96.561  79.407  1.00 142.34 ? 181 LEU B CG  1 
ATOM   4671  C CD1 . LEU B 2 181 ? 119.733 96.823  78.563  1.00 268.81 ? 181 LEU B CD1 1 
ATOM   4672  C CD2 . LEU B 2 181 ? 118.766 95.366  80.289  1.00 225.60 ? 181 LEU B CD2 1 
ATOM   4673  N N   . LEU B 2 182 ? 115.273 98.138  78.885  1.00 111.33 ? 182 LEU B N   1 
ATOM   4674  C CA  . LEU B 2 182 ? 114.246 97.573  78.034  1.00 143.67 ? 182 LEU B CA  1 
ATOM   4675  C C   . LEU B 2 182 ? 113.726 98.579  76.996  1.00 165.93 ? 182 LEU B C   1 
ATOM   4676  O O   . LEU B 2 182 ? 113.251 98.158  75.940  1.00 202.95 ? 182 LEU B O   1 
ATOM   4677  C CB  . LEU B 2 182 ? 113.126 97.037  78.922  1.00 159.77 ? 182 LEU B CB  1 
ATOM   4678  C CG  . LEU B 2 182 ? 113.529 95.773  79.662  1.00 184.55 ? 182 LEU B CG  1 
ATOM   4679  C CD1 . LEU B 2 182 ? 112.439 95.384  80.657  1.00 264.70 ? 182 LEU B CD1 1 
ATOM   4680  C CD2 . LEU B 2 182 ? 113.834 94.632  78.705  1.00 159.62 ? 182 LEU B CD2 1 
ATOM   4681  N N   . THR B 2 183 ? 113.811 99.889  77.252  1.00 134.93 ? 183 THR B N   1 
ATOM   4682  C CA  . THR B 2 183 ? 113.558 100.849 76.190  1.00 152.63 ? 183 THR B CA  1 
ATOM   4683  C C   . THR B 2 183 ? 114.612 100.734 75.094  1.00 155.17 ? 183 THR B C   1 
ATOM   4684  O O   . THR B 2 183 ? 114.276 100.754 73.918  1.00 191.18 ? 183 THR B O   1 
ATOM   4685  C CB  . THR B 2 183 ? 113.549 102.284 76.711  1.00 157.05 ? 183 THR B CB  1 
ATOM   4686  O OG1 . THR B 2 183 ? 112.519 102.335 77.682  1.00 169.79 ? 183 THR B OG1 1 
ATOM   4687  C CG2 . THR B 2 183 ? 113.245 103.336 75.665  1.00 211.25 ? 183 THR B CG2 1 
ATOM   4688  N N   . ALA B 2 184 ? 115.881 100.653 75.468  1.00 122.61 ? 184 ALA B N   1 
ATOM   4689  C CA  . ALA B 2 184 ? 116.923 100.526 74.473  1.00 161.73 ? 184 ALA B CA  1 
ATOM   4690  C C   . ALA B 2 184 ? 116.817 99.211  73.666  1.00 145.13 ? 184 ALA B C   1 
ATOM   4691  O O   . ALA B 2 184 ? 116.991 99.232  72.442  1.00 260.87 ? 184 ALA B O   1 
ATOM   4692  C CB  . ALA B 2 184 ? 118.251 100.663 75.166  1.00 235.26 ? 184 ALA B CB  1 
ATOM   4693  N N   . VAL B 2 185 ? 116.564 98.066  74.306  1.00 126.32 ? 185 VAL B N   1 
ATOM   4694  C CA  . VAL B 2 185 ? 116.346 96.817  73.593  1.00 130.18 ? 185 VAL B CA  1 
ATOM   4695  C C   . VAL B 2 185 ? 115.155 96.947  72.654  1.00 144.93 ? 185 VAL B C   1 
ATOM   4696  O O   . VAL B 2 185 ? 115.277 96.531  71.504  1.00 234.93 ? 185 VAL B O   1 
ATOM   4697  C CB  . VAL B 2 185 ? 116.134 95.631  74.544  1.00 200.50 ? 185 VAL B CB  1 
ATOM   4698  C CG1 . VAL B 2 185 ? 115.353 94.454  73.904  1.00 174.84 ? 185 VAL B CG1 1 
ATOM   4699  C CG2 . VAL B 2 185 ? 117.490 95.219  75.112  1.00 230.83 ? 185 VAL B CG2 1 
ATOM   4700  N N   . ASN B 2 186 ? 114.054 97.538  73.127  1.00 152.87 ? 186 ASN B N   1 
ATOM   4701  C CA  . ASN B 2 186 ? 112.849 97.656  72.327  1.00 183.66 ? 186 ASN B CA  1 
ATOM   4702  C C   . ASN B 2 186 ? 113.088 98.609  71.133  1.00 204.36 ? 186 ASN B C   1 
ATOM   4703  O O   . ASN B 2 186 ? 112.445 98.449  70.092  1.00 237.49 ? 186 ASN B O   1 
ATOM   4704  C CB  . ASN B 2 186 ? 111.646 97.983  73.225  1.00 178.36 ? 186 ASN B CB  1 
ATOM   4705  C CG  . ASN B 2 186 ? 110.347 97.385  72.717  1.00 193.07 ? 186 ASN B CG  1 
ATOM   4706  O OD1 . ASN B 2 186 ? 109.824 97.786  71.679  1.00 137.21 ? 186 ASN B OD1 1 
ATOM   4707  N ND2 . ASN B 2 186 ? 109.810 96.418  73.441  1.00 194.50 ? 186 ASN B ND2 1 
ATOM   4708  N N   . CYS B 2 187 ? 114.010 99.585  71.253  1.00 160.02 ? 187 CYS B N   1 
ATOM   4709  C CA  . CYS B 2 187 ? 114.399 100.442 70.133  1.00 224.58 ? 187 CYS B CA  1 
ATOM   4710  C C   . CYS B 2 187 ? 115.334 99.778  69.108  1.00 196.89 ? 187 CYS B C   1 
ATOM   4711  O O   . CYS B 2 187 ? 115.324 100.187 67.952  1.00 252.20 ? 187 CYS B O   1 
ATOM   4712  C CB  . CYS B 2 187 ? 115.054 101.728 70.633  1.00 254.07 ? 187 CYS B CB  1 
ATOM   4713  S SG  . CYS B 2 187 ? 113.868 102.892 71.358  1.00 241.04 ? 187 CYS B SG  1 
ATOM   4714  N N   . TYR B 2 188 ? 116.142 98.787  69.475  1.00 159.53 ? 188 TYR B N   1 
ATOM   4715  C CA  . TYR B 2 188 ? 117.098 98.209  68.537  1.00 150.56 ? 188 TYR B CA  1 
ATOM   4716  C C   . TYR B 2 188 ? 116.433 97.192  67.621  1.00 170.03 ? 188 TYR B C   1 
ATOM   4717  O O   . TYR B 2 188 ? 116.847 97.134  66.457  1.00 340.60 ? 188 TYR B O   1 
ATOM   4718  C CB  . TYR B 2 188 ? 118.326 97.568  69.199  1.00 192.97 ? 188 TYR B CB  1 
ATOM   4719  C CG  . TYR B 2 188 ? 119.493 98.536  69.420  1.00 282.35 ? 188 TYR B CG  1 
ATOM   4720  C CD1 . TYR B 2 188 ? 119.335 99.938  69.483  1.00 298.86 ? 188 TYR B CD1 1 
ATOM   4721  C CD2 . TYR B 2 188 ? 120.796 98.037  69.539  1.00 290.22 ? 188 TYR B CD2 1 
ATOM   4722  C CE1 . TYR B 2 188 ? 120.414 100.793 69.681  1.00 262.91 ? 188 TYR B CE1 1 
ATOM   4723  C CE2 . TYR B 2 188 ? 121.882 98.886  69.735  1.00 304.71 ? 188 TYR B CE2 1 
ATOM   4724  C CZ  . TYR B 2 188 ? 121.690 100.262 69.805  1.00 279.57 ? 188 TYR B CZ  1 
ATOM   4725  O OH  . TYR B 2 188 ? 122.745 101.103 69.993  1.00 252.34 ? 188 TYR B OH  1 
ATOM   4726  N N   . SER B 2 189 ? 115.438 96.424  68.078  1.00 156.33 ? 189 SER B N   1 
ATOM   4727  C CA  . SER B 2 189 ? 114.922 95.361  67.231  1.00 201.58 ? 189 SER B CA  1 
ATOM   4728  C C   . SER B 2 189 ? 113.685 94.713  67.805  1.00 196.95 ? 189 SER B C   1 
ATOM   4729  O O   . SER B 2 189 ? 113.747 94.218  68.933  1.00 281.06 ? 189 SER B O   1 
ATOM   4730  C CB  . SER B 2 189 ? 115.946 94.262  67.024  1.00 232.21 ? 189 SER B CB  1 
ATOM   4731  O OG  . SER B 2 189 ? 115.383 93.178  66.275  1.00 257.66 ? 189 SER B OG  1 
ATOM   4732  N N   . VAL B 2 190 ? 112.606 94.655  67.020  1.00 159.72 ? 190 VAL B N   1 
ATOM   4733  C CA  . VAL B 2 190 ? 111.431 93.915  67.479  1.00 219.47 ? 190 VAL B CA  1 
ATOM   4734  C C   . VAL B 2 190 ? 111.711 92.397  67.608  1.00 193.46 ? 190 VAL B C   1 
ATOM   4735  O O   . VAL B 2 190 ? 111.111 91.736  68.479  1.00 159.63 ? 190 VAL B O   1 
ATOM   4736  C CB  . VAL B 2 190 ? 110.197 94.255  66.624  1.00 240.55 ? 190 VAL B CB  1 
ATOM   4737  C CG1 . VAL B 2 190 ? 108.952 93.522  67.108  1.00 232.54 ? 190 VAL B CG1 1 
ATOM   4738  C CG2 . VAL B 2 190 ? 109.960 95.759  66.619  1.00 217.98 ? 190 VAL B CG2 1 
ATOM   4739  N N   . LYS B 2 191 ? 112.626 91.859  66.783  1.00 195.72 ? 191 LYS B N   1 
ATOM   4740  C CA  . LYS B 2 191 ? 113.060 90.475  66.924  1.00 279.15 ? 191 LYS B CA  1 
ATOM   4741  C C   . LYS B 2 191 ? 114.008 90.262  68.111  1.00 273.32 ? 191 LYS B C   1 
ATOM   4742  O O   . LYS B 2 191 ? 114.283 89.105  68.444  1.00 283.97 ? 191 LYS B O   1 
ATOM   4743  C CB  . LYS B 2 191 ? 113.690 89.994  65.610  1.00 349.32 ? 191 LYS B CB  1 
ATOM   4744  C CG  . LYS B 2 191 ? 112.680 89.652  64.520  1.00 426.60 ? 191 LYS B CG  1 
ATOM   4745  C CD  . LYS B 2 191 ? 111.834 88.393  64.761  1.00 451.52 ? 191 LYS B CD  1 
ATOM   4746  C CE  . LYS B 2 191 ? 112.611 87.089  64.730  1.00 447.14 ? 191 LYS B CE  1 
ATOM   4747  N NZ  . LYS B 2 191 ? 111.724 85.917  64.920  1.00 421.27 ? 191 LYS B NZ  1 
ATOM   4748  N N   . ALA B 2 192 ? 114.511 91.338  68.743  1.00 248.57 ? 192 ALA B N   1 
ATOM   4749  C CA  . ALA B 2 192 ? 115.090 91.240  70.073  1.00 268.64 ? 192 ALA B CA  1 
ATOM   4750  C C   . ALA B 2 192 ? 113.966 91.221  71.100  1.00 216.47 ? 192 ALA B C   1 
ATOM   4751  O O   . ALA B 2 192 ? 113.855 90.281  71.869  1.00 165.86 ? 192 ALA B O   1 
ATOM   4752  C CB  . ALA B 2 192 ? 116.055 92.366  70.351  1.00 323.98 ? 192 ALA B CB  1 
ATOM   4753  N N   . ALA B 2 193 ? 113.134 92.261  71.112  1.00 215.45 ? 193 ALA B N   1 
ATOM   4754  C CA  . ALA B 2 193 ? 112.168 92.442  72.183  1.00 188.95 ? 193 ALA B CA  1 
ATOM   4755  C C   . ALA B 2 193 ? 111.141 91.302  72.252  1.00 195.52 ? 193 ALA B C   1 
ATOM   4756  O O   . ALA B 2 193 ? 110.738 90.953  73.364  1.00 274.83 ? 193 ALA B O   1 
ATOM   4757  C CB  . ALA B 2 193 ? 111.504 93.776  72.035  1.00 160.67 ? 193 ALA B CB  1 
ATOM   4758  N N   . THR B 2 194 ? 110.719 90.713  71.122  1.00 161.08 ? 194 THR B N   1 
ATOM   4759  C CA  . THR B 2 194 ? 109.850 89.538  71.178  1.00 202.23 ? 194 THR B CA  1 
ATOM   4760  C C   . THR B 2 194 ? 110.579 88.288  71.695  1.00 200.88 ? 194 THR B C   1 
ATOM   4761  O O   . THR B 2 194 ? 109.982 87.493  72.424  1.00 253.02 ? 194 THR B O   1 
ATOM   4762  C CB  . THR B 2 194 ? 109.198 89.202  69.830  1.00 270.29 ? 194 THR B CB  1 
ATOM   4763  O OG1 . THR B 2 194 ? 110.201 89.177  68.811  1.00 314.40 ? 194 THR B OG1 1 
ATOM   4764  C CG2 . THR B 2 194 ? 108.113 90.188  69.470  1.00 262.01 ? 194 THR B CG2 1 
ATOM   4765  N N   . ARG B 2 195 ? 111.848 88.085  71.335  1.00 176.91 ? 195 ARG B N   1 
ATOM   4766  C CA  . ARG B 2 195 ? 112.596 86.973  71.912  1.00 238.44 ? 195 ARG B CA  1 
ATOM   4767  C C   . ARG B 2 195 ? 112.795 87.191  73.423  1.00 245.32 ? 195 ARG B C   1 
ATOM   4768  O O   . ARG B 2 195 ? 112.748 86.241  74.193  1.00 209.71 ? 195 ARG B O   1 
ATOM   4769  C CB  . ARG B 2 195 ? 113.930 86.790  71.176  1.00 341.16 ? 195 ARG B CB  1 
ATOM   4770  C CG  . ARG B 2 195 ? 113.824 86.129  69.811  1.00 382.22 ? 195 ARG B CG  1 
ATOM   4771  C CD  . ARG B 2 195 ? 115.206 85.908  69.204  1.00 415.09 ? 195 ARG B CD  1 
ATOM   4772  N NE  . ARG B 2 195 ? 115.980 84.847  69.853  1.00 422.25 ? 195 ARG B NE  1 
ATOM   4773  C CZ  . ARG B 2 195 ? 117.302 84.674  69.754  1.00 385.29 ? 195 ARG B CZ  1 
ATOM   4774  N NH1 . ARG B 2 195 ? 117.885 83.646  70.350  1.00 342.61 ? 195 ARG B NH1 1 
ATOM   4775  N NH2 . ARG B 2 195 ? 118.045 85.523  69.062  1.00 384.37 ? 195 ARG B NH2 1 
ATOM   4776  N N   . VAL B 2 196 ? 113.022 88.438  73.867  1.00 219.51 ? 196 VAL B N   1 
ATOM   4777  C CA  . VAL B 2 196 ? 113.097 88.775  75.286  1.00 175.70 ? 196 VAL B CA  1 
ATOM   4778  C C   . VAL B 2 196 ? 111.769 88.474  75.978  1.00 160.28 ? 196 VAL B C   1 
ATOM   4779  O O   . VAL B 2 196 ? 111.773 87.983  77.102  1.00 166.00 ? 196 VAL B O   1 
ATOM   4780  C CB  . VAL B 2 196 ? 113.525 90.246  75.487  1.00 159.71 ? 196 VAL B CB  1 
ATOM   4781  C CG1 . VAL B 2 196 ? 113.256 90.757  76.890  1.00 173.98 ? 196 VAL B CG1 1 
ATOM   4782  C CG2 . VAL B 2 196 ? 114.992 90.450  75.145  1.00 207.23 ? 196 VAL B CG2 1 
ATOM   4783  N N   . GLN B 2 197 ? 110.647 88.769  75.319  1.00 178.46 ? 197 GLN B N   1 
ATOM   4784  C CA  . GLN B 2 197 ? 109.326 88.451  75.840  1.00 179.70 ? 197 GLN B CA  1 
ATOM   4785  C C   . GLN B 2 197 ? 109.139 86.941  75.971  1.00 147.82 ? 197 GLN B C   1 
ATOM   4786  O O   . GLN B 2 197 ? 108.645 86.489  76.997  1.00 173.80 ? 197 GLN B O   1 
ATOM   4787  C CB  . GLN B 2 197 ? 108.253 89.067  74.945  1.00 192.48 ? 197 GLN B CB  1 
ATOM   4788  C CG  . GLN B 2 197 ? 106.851 88.896  75.482  1.00 178.07 ? 197 GLN B CG  1 
ATOM   4789  C CD  . GLN B 2 197 ? 106.655 89.722  76.724  1.00 200.86 ? 197 GLN B CD  1 
ATOM   4790  O OE1 . GLN B 2 197 ? 106.691 89.197  77.832  1.00 238.50 ? 197 GLN B OE1 1 
ATOM   4791  N NE2 . GLN B 2 197 ? 106.464 91.017  76.546  1.00 154.78 ? 197 GLN B NE2 1 
ATOM   4792  N N   . ASP B 2 198 ? 109.543 86.176  74.960  1.00 162.52 ? 198 ASP B N   1 
ATOM   4793  C CA  . ASP B 2 198 ? 109.477 84.724  75.022  1.00 265.81 ? 198 ASP B CA  1 
ATOM   4794  C C   . ASP B 2 198 ? 110.310 84.244  76.212  1.00 188.11 ? 198 ASP B C   1 
ATOM   4795  O O   . ASP B 2 198 ? 109.842 83.436  77.010  1.00 168.26 ? 198 ASP B O   1 
ATOM   4796  C CB  . ASP B 2 198 ? 109.913 84.095  73.687  1.00 387.31 ? 198 ASP B CB  1 
ATOM   4797  C CG  . ASP B 2 198 ? 109.821 82.575  73.596  1.00 440.67 ? 198 ASP B CG  1 
ATOM   4798  O OD1 . ASP B 2 198 ? 108.996 81.969  74.320  1.00 422.23 ? 198 ASP B OD1 1 
ATOM   4799  O OD2 . ASP B 2 198 ? 110.583 81.999  72.796  1.00 430.03 ? 198 ASP B OD2 1 
ATOM   4800  N N   . ALA B 2 199 ? 111.545 84.746  76.324  1.00 154.93 ? 199 ALA B N   1 
ATOM   4801  C CA  . ALA B 2 199 ? 112.492 84.317  77.341  1.00 217.92 ? 199 ALA B CA  1 
ATOM   4802  C C   . ALA B 2 199 ? 111.892 84.466  78.735  1.00 177.49 ? 199 ALA B C   1 
ATOM   4803  O O   . ALA B 2 199 ? 111.918 83.532  79.535  1.00 225.20 ? 199 ALA B O   1 
ATOM   4804  C CB  . ALA B 2 199 ? 113.792 85.090  77.207  1.00 236.80 ? 199 ALA B CB  1 
ATOM   4805  N N   . PHE B 2 200 ? 111.353 85.640  79.032  1.00 173.67 ? 200 PHE B N   1 
ATOM   4806  C CA  . PHE B 2 200 ? 110.856 85.885  80.377  1.00 216.21 ? 200 PHE B CA  1 
ATOM   4807  C C   . PHE B 2 200 ? 109.415 85.399  80.578  1.00 193.07 ? 200 PHE B C   1 
ATOM   4808  O O   . PHE B 2 200 ? 109.031 85.178  81.722  1.00 212.90 ? 200 PHE B O   1 
ATOM   4809  C CB  . PHE B 2 200 ? 111.080 87.343  80.750  1.00 234.33 ? 200 PHE B CB  1 
ATOM   4810  C CG  . PHE B 2 200 ? 112.535 87.671  80.932  1.00 187.12 ? 200 PHE B CG  1 
ATOM   4811  C CD1 . PHE B 2 200 ? 113.277 87.061  81.928  1.00 213.07 ? 200 PHE B CD1 1 
ATOM   4812  C CD2 . PHE B 2 200 ? 113.161 88.562  80.093  1.00 206.19 ? 200 PHE B CD2 1 
ATOM   4813  C CE1 . PHE B 2 200 ? 114.620 87.352  82.101  1.00 261.44 ? 200 PHE B CE1 1 
ATOM   4814  C CE2 . PHE B 2 200 ? 114.505 88.855  80.261  1.00 250.69 ? 200 PHE B CE2 1 
ATOM   4815  C CZ  . PHE B 2 200 ? 115.234 88.250  81.261  1.00 261.37 ? 200 PHE B CZ  1 
ATOM   4816  N N   . ALA B 2 201 ? 108.618 85.212  79.517  1.00 166.58 ? 201 ALA B N   1 
ATOM   4817  C CA  . ALA B 2 201 ? 107.339 84.516  79.653  1.00 195.85 ? 201 ALA B CA  1 
ATOM   4818  C C   . ALA B 2 201 ? 107.561 83.050  80.045  1.00 195.34 ? 201 ALA B C   1 
ATOM   4819  O O   . ALA B 2 201 ? 106.773 82.500  80.810  1.00 178.50 ? 201 ALA B O   1 
ATOM   4820  C CB  . ALA B 2 201 ? 106.522 84.641  78.396  1.00 225.55 ? 201 ALA B CB  1 
ATOM   4821  N N   . ALA B 2 202 ? 108.633 82.427  79.529  1.00 183.28 ? 202 ALA B N   1 
ATOM   4822  C CA  . ALA B 2 202 ? 109.016 81.075  79.909  1.00 246.03 ? 202 ALA B CA  1 
ATOM   4823  C C   . ALA B 2 202 ? 109.459 81.054  81.367  1.00 223.22 ? 202 ALA B C   1 
ATOM   4824  O O   . ALA B 2 202 ? 108.980 80.218  82.131  1.00 183.03 ? 202 ALA B O   1 
ATOM   4825  C CB  . ALA B 2 202 ? 110.105 80.542  78.993  1.00 276.33 ? 202 ALA B CB  1 
ATOM   4826  N N   . ALA B 2 203 ? 110.363 81.977  81.729  1.00 238.74 ? 203 ALA B N   1 
ATOM   4827  C CA  . ALA B 2 203 ? 110.983 82.016  83.046  1.00 265.49 ? 203 ALA B CA  1 
ATOM   4828  C C   . ALA B 2 203 ? 109.914 82.084  84.134  1.00 209.20 ? 203 ALA B C   1 
ATOM   4829  O O   . ALA B 2 203 ? 109.944 81.274  85.073  1.00 289.15 ? 203 ALA B O   1 
ATOM   4830  C CB  . ALA B 2 203 ? 111.965 83.166  83.154  1.00 258.41 ? 203 ALA B CB  1 
ATOM   4831  N N   . LYS B 2 204 ? 108.972 83.025  84.010  1.00 129.66 ? 204 LYS B N   1 
ATOM   4832  C CA  . LYS B 2 204 ? 107.963 83.140  85.054  1.00 205.45 ? 204 LYS B CA  1 
ATOM   4833  C C   . LYS B 2 204 ? 107.028 81.928  85.163  1.00 202.71 ? 204 LYS B C   1 
ATOM   4834  O O   . LYS B 2 204 ? 106.602 81.616  86.279  1.00 265.12 ? 204 LYS B O   1 
ATOM   4835  C CB  . LYS B 2 204 ? 107.141 84.413  84.892  1.00 208.34 ? 204 LYS B CB  1 
ATOM   4836  C CG  . LYS B 2 204 ? 106.185 84.473  83.726  1.00 193.57 ? 204 LYS B CG  1 
ATOM   4837  C CD  . LYS B 2 204 ? 105.687 85.876  83.575  1.00 160.29 ? 204 LYS B CD  1 
ATOM   4838  C CE  . LYS B 2 204 ? 106.727 86.747  82.908  1.00 272.62 ? 204 LYS B CE  1 
ATOM   4839  N NZ  . LYS B 2 204 ? 106.324 88.155  82.990  1.00 266.33 ? 204 LYS B NZ  1 
ATOM   4840  N N   . LEU B 2 205 ? 106.715 81.249  84.054  1.00 168.05 ? 205 LEU B N   1 
ATOM   4841  C CA  . LEU B 2 205 ? 105.894 80.046  84.144  1.00 225.12 ? 205 LEU B CA  1 
ATOM   4842  C C   . LEU B 2 205 ? 106.658 78.900  84.818  1.00 259.12 ? 205 LEU B C   1 
ATOM   4843  O O   . LEU B 2 205 ? 106.018 78.134  85.540  1.00 291.77 ? 205 LEU B O   1 
ATOM   4844  C CB  . LEU B 2 205 ? 105.398 79.636  82.756  1.00 261.99 ? 205 LEU B CB  1 
ATOM   4845  C CG  . LEU B 2 205 ? 104.322 80.542  82.157  1.00 288.10 ? 205 LEU B CG  1 
ATOM   4846  C CD1 . LEU B 2 205 ? 104.027 80.128  80.722  1.00 354.89 ? 205 LEU B CD1 1 
ATOM   4847  C CD2 . LEU B 2 205 ? 103.040 80.536  82.990  1.00 229.83 ? 205 LEU B CD2 1 
ATOM   4848  N N   . LEU B 2 206 ? 107.986 78.780  84.605  1.00 218.99 ? 206 LEU B N   1 
ATOM   4849  C CA  . LEU B 2 206 ? 108.801 77.837  85.374  1.00 243.16 ? 206 LEU B CA  1 
ATOM   4850  C C   . LEU B 2 206 ? 108.726 78.131  86.878  1.00 230.22 ? 206 LEU B C   1 
ATOM   4851  O O   . LEU B 2 206 ? 108.527 77.210  87.681  1.00 239.93 ? 206 LEU B O   1 
ATOM   4852  C CB  . LEU B 2 206 ? 110.260 77.869  84.896  1.00 279.70 ? 206 LEU B CB  1 
ATOM   4853  C CG  . LEU B 2 206 ? 110.521 77.325  83.492  1.00 410.28 ? 206 LEU B CG  1 
ATOM   4854  C CD1 . LEU B 2 206 ? 111.981 77.530  83.111  1.00 432.42 ? 206 LEU B CD1 1 
ATOM   4855  C CD2 . LEU B 2 206 ? 110.143 75.850  83.374  1.00 489.66 ? 206 LEU B CD2 1 
ATOM   4856  N N   . ALA B 2 207 ? 108.873 79.410  87.250  1.00 231.66 ? 207 ALA B N   1 
ATOM   4857  C CA  . ALA B 2 207 ? 108.782 79.823  88.646  1.00 231.86 ? 207 ALA B CA  1 
ATOM   4858  C C   . ALA B 2 207 ? 107.403 79.505  89.245  1.00 184.40 ? 207 ALA B C   1 
ATOM   4859  O O   . ALA B 2 207 ? 107.332 78.961  90.354  1.00 243.79 ? 207 ALA B O   1 
ATOM   4860  C CB  . ALA B 2 207 ? 109.115 81.285  88.774  1.00 234.04 ? 207 ALA B CB  1 
ATOM   4861  N N   . LEU B 2 208 ? 106.322 79.831  88.522  1.00 132.72 ? 208 LEU B N   1 
ATOM   4862  C CA  . LEU B 2 208 ? 104.971 79.524  88.984  1.00 187.79 ? 208 LEU B CA  1 
ATOM   4863  C C   . LEU B 2 208 ? 104.730 78.016  89.036  1.00 217.16 ? 208 LEU B C   1 
ATOM   4864  O O   . LEU B 2 208 ? 104.015 77.566  89.932  1.00 242.36 ? 208 LEU B O   1 
ATOM   4865  C CB  . LEU B 2 208 ? 103.944 80.267  88.120  1.00 199.89 ? 208 LEU B CB  1 
ATOM   4866  C CG  . LEU B 2 208 ? 103.899 81.759  88.450  1.00 206.71 ? 208 LEU B CG  1 
ATOM   4867  C CD1 . LEU B 2 208 ? 103.446 82.584  87.263  1.00 229.37 ? 208 LEU B CD1 1 
ATOM   4868  C CD2 . LEU B 2 208 ? 102.997 82.026  89.650  1.00 201.56 ? 208 LEU B CD2 1 
ATOM   4869  N N   . ALA B 2 209 ? 105.343 77.248  88.123  1.00 244.50 ? 209 ALA B N   1 
ATOM   4870  C CA  . ALA B 2 209 ? 105.311 75.794  88.217  1.00 298.02 ? 209 ALA B CA  1 
ATOM   4871  C C   . ALA B 2 209 ? 105.937 75.307  89.531  1.00 249.83 ? 209 ALA B C   1 
ATOM   4872  O O   . ALA B 2 209 ? 105.319 74.447  90.171  1.00 164.88 ? 209 ALA B O   1 
ATOM   4873  C CB  . ALA B 2 209 ? 105.963 75.154  87.008  1.00 367.99 ? 209 ALA B CB  1 
ATOM   4874  N N   . LEU B 2 210 ? 107.116 75.849  89.933  1.00 249.14 ? 210 LEU B N   1 
ATOM   4875  C CA  . LEU B 2 210 ? 107.760 75.477  91.201  1.00 231.06 ? 210 LEU B CA  1 
ATOM   4876  C C   . LEU B 2 210 ? 106.835 75.759  92.379  1.00 193.67 ? 210 LEU B C   1 
ATOM   4877  O O   . LEU B 2 210 ? 106.676 74.904  93.249  1.00 250.71 ? 210 LEU B O   1 
ATOM   4878  C CB  . LEU B 2 210 ? 109.097 76.198  91.432  1.00 190.46 ? 210 LEU B CB  1 
ATOM   4879  C CG  . LEU B 2 210 ? 110.261 75.750  90.540  1.00 261.14 ? 210 LEU B CG  1 
ATOM   4880  C CD1 . LEU B 2 210 ? 111.491 76.612  90.759  1.00 270.93 ? 210 LEU B CD1 1 
ATOM   4881  C CD2 . LEU B 2 210 ? 110.628 74.290  90.765  1.00 331.80 ? 210 LEU B CD2 1 
ATOM   4882  N N   . ILE B 2 211 ? 106.227 76.945  92.386  1.00 185.63 ? 211 ILE B N   1 
ATOM   4883  C CA  . ILE B 2 211 ? 105.342 77.338  93.472  1.00 222.33 ? 211 ILE B CA  1 
ATOM   4884  C C   . ILE B 2 211 ? 104.121 76.400  93.533  1.00 242.46 ? 211 ILE B C   1 
ATOM   4885  O O   . ILE B 2 211 ? 103.791 75.908  94.618  1.00 343.87 ? 211 ILE B O   1 
ATOM   4886  C CB  . ILE B 2 211 ? 105.032 78.850  93.363  1.00 186.80 ? 211 ILE B CB  1 
ATOM   4887  C CG1 . ILE B 2 211 ? 106.324 79.627  93.669  1.00 188.29 ? 211 ILE B CG1 1 
ATOM   4888  C CG2 . ILE B 2 211 ? 103.866 79.276  94.255  1.00 159.82 ? 211 ILE B CG2 1 
ATOM   4889  C CD1 . ILE B 2 211 ? 106.292 81.097  93.328  1.00 237.22 ? 211 ILE B CD1 1 
ATOM   4890  N N   . ILE B 2 212 ? 103.472 76.117  92.398  1.00 183.74 ? 212 ILE B N   1 
ATOM   4891  C CA  . ILE B 2 212 ? 102.326 75.213  92.394  1.00 219.68 ? 212 ILE B CA  1 
ATOM   4892  C C   . ILE B 2 212 ? 102.760 73.797  92.804  1.00 244.22 ? 212 ILE B C   1 
ATOM   4893  O O   . ILE B 2 212 ? 102.056 73.141  93.592  1.00 319.57 ? 212 ILE B O   1 
ATOM   4894  C CB  . ILE B 2 212 ? 101.619 75.235  91.025  1.00 255.93 ? 212 ILE B CB  1 
ATOM   4895  C CG1 . ILE B 2 212 ? 100.996 76.603  90.747  1.00 256.13 ? 212 ILE B CG1 1 
ATOM   4896  C CG2 . ILE B 2 212 ? 100.581 74.118  90.918  1.00 284.45 ? 212 ILE B CG2 1 
ATOM   4897  C CD1 . ILE B 2 212 ? 100.702 76.882  89.289  1.00 293.07 ? 212 ILE B CD1 1 
ATOM   4898  N N   . LEU B 2 213 ? 103.905 73.335  92.270  1.00 218.45 ? 213 LEU B N   1 
ATOM   4899  C CA  . LEU B 2 213 ? 104.435 72.003  92.560  1.00 281.88 ? 213 LEU B CA  1 
ATOM   4900  C C   . LEU B 2 213 ? 104.690 71.813  94.062  1.00 268.23 ? 213 LEU B C   1 
ATOM   4901  O O   . LEU B 2 213 ? 104.316 70.776  94.613  1.00 237.57 ? 213 LEU B O   1 
ATOM   4902  C CB  . LEU B 2 213 ? 105.715 71.786  91.737  1.00 348.74 ? 213 LEU B CB  1 
ATOM   4903  C CG  . LEU B 2 213 ? 106.506 70.500  91.998  1.00 362.23 ? 213 LEU B CG  1 
ATOM   4904  C CD1 . LEU B 2 213 ? 105.692 69.267  91.631  1.00 394.45 ? 213 LEU B CD1 1 
ATOM   4905  C CD2 . LEU B 2 213 ? 107.822 70.505  91.228  1.00 312.64 ? 213 LEU B CD2 1 
ATOM   4906  N N   . LEU B 2 214 ? 105.328 72.798  94.714  1.00 272.21 ? 214 LEU B N   1 
ATOM   4907  C CA  . LEU B 2 214 ? 105.585 72.731  96.149  1.00 236.52 ? 214 LEU B CA  1 
ATOM   4908  C C   . LEU B 2 214 ? 104.272 72.740  96.940  1.00 235.21 ? 214 LEU B C   1 
ATOM   4909  O O   . LEU B 2 214 ? 104.204 72.067  97.973  1.00 374.35 ? 214 LEU B O   1 
ATOM   4910  C CB  . LEU B 2 214 ? 106.532 73.866  96.549  1.00 292.38 ? 214 LEU B CB  1 
ATOM   4911  C CG  . LEU B 2 214 ? 107.959 73.714  96.014  1.00 352.68 ? 214 LEU B CG  1 
ATOM   4912  C CD1 . LEU B 2 214 ? 108.720 75.032  96.090  1.00 374.95 ? 214 LEU B CD1 1 
ATOM   4913  C CD2 . LEU B 2 214 ? 108.715 72.616  96.756  1.00 356.94 ? 214 LEU B CD2 1 
ATOM   4914  N N   . GLY B 2 215 ? 103.239 73.454  96.455  1.00 221.69 ? 215 GLY B N   1 
ATOM   4915  C CA  . GLY B 2 215 ? 101.870 73.327  96.960  1.00 241.46 ? 215 GLY B CA  1 
ATOM   4916  C C   . GLY B 2 215 ? 101.312 71.895  96.889  1.00 311.36 ? 215 GLY B C   1 
ATOM   4917  O O   . GLY B 2 215 ? 100.800 71.364  97.886  1.00 298.44 ? 215 GLY B O   1 
ATOM   4918  N N   . PHE B 2 216 ? 101.426 71.272  95.703  1.00 373.37 ? 216 PHE B N   1 
ATOM   4919  C CA  . PHE B 2 216 ? 100.986 69.895  95.484  1.00 390.87 ? 216 PHE B CA  1 
ATOM   4920  C C   . PHE B 2 216 ? 101.762 68.891  96.351  1.00 367.10 ? 216 PHE B C   1 
ATOM   4921  O O   . PHE B 2 216 ? 101.143 67.975  96.894  1.00 369.54 ? 216 PHE B O   1 
ATOM   4922  C CB  . PHE B 2 216 ? 101.084 69.525  93.995  1.00 424.91 ? 216 PHE B CB  1 
ATOM   4923  C CG  . PHE B 2 216 ? 100.037 70.083  93.056  1.00 476.49 ? 216 PHE B CG  1 
ATOM   4924  C CD1 . PHE B 2 216 ? 98.999  70.917  93.477  1.00 506.40 ? 216 PHE B CD1 1 
ATOM   4925  C CD2 . PHE B 2 216 ? 100.096 69.751  91.706  1.00 495.74 ? 216 PHE B CD2 1 
ATOM   4926  C CE1 . PHE B 2 216 ? 98.060  71.399  92.574  1.00 527.58 ? 216 PHE B CE1 1 
ATOM   4927  C CE2 . PHE B 2 216 ? 99.158  70.238  90.805  1.00 528.29 ? 216 PHE B CE2 1 
ATOM   4928  C CZ  . PHE B 2 216 ? 98.141  71.060  91.240  1.00 544.69 ? 216 PHE B CZ  1 
ATOM   4929  N N   . VAL B 2 217 ? 103.095 69.060  96.477  1.00 346.60 ? 217 VAL B N   1 
ATOM   4930  C CA  . VAL B 2 217 ? 103.943 68.243  97.349  1.00 308.47 ? 217 VAL B CA  1 
ATOM   4931  C C   . VAL B 2 217 ? 103.439 68.309  98.797  1.00 283.71 ? 217 VAL B C   1 
ATOM   4932  O O   . VAL B 2 217 ? 103.295 67.263  99.446  1.00 317.34 ? 217 VAL B O   1 
ATOM   4933  C CB  . VAL B 2 217 ? 105.433 68.650  97.222  1.00 325.39 ? 217 VAL B CB  1 
ATOM   4934  C CG1 . VAL B 2 217 ? 106.315 68.169  98.373  1.00 315.67 ? 217 VAL B CG1 1 
ATOM   4935  C CG2 . VAL B 2 217 ? 106.022 68.176  95.901  1.00 337.95 ? 217 VAL B CG2 1 
ATOM   4936  N N   . GLN B 2 218 ? 103.171 69.531  99.285  1.00 294.69 ? 218 GLN B N   1 
ATOM   4937  C CA  . GLN B 2 218 ? 102.750 69.762  100.662 1.00 283.83 ? 218 GLN B CA  1 
ATOM   4938  C C   . GLN B 2 218 ? 101.376 69.147  100.963 1.00 356.78 ? 218 GLN B C   1 
ATOM   4939  O O   . GLN B 2 218 ? 101.261 68.424  101.957 1.00 468.35 ? 218 GLN B O   1 
ATOM   4940  C CB  . GLN B 2 218 ? 102.751 71.261  100.936 1.00 326.67 ? 218 GLN B CB  1 
ATOM   4941  C CG  . GLN B 2 218 ? 102.286 71.663  102.327 1.00 339.14 ? 218 GLN B CG  1 
ATOM   4942  C CD  . GLN B 2 218 ? 102.678 73.096  102.589 1.00 339.64 ? 218 GLN B CD  1 
ATOM   4943  O OE1 . GLN B 2 218 ? 103.343 73.405  103.575 1.00 312.53 ? 218 GLN B OE1 1 
ATOM   4944  N NE2 . GLN B 2 218 ? 102.286 73.981  101.687 1.00 341.41 ? 218 GLN B NE2 1 
ATOM   4945  N N   . ILE B 2 219 ? 100.348 69.418  100.137 1.00 320.25 ? 219 ILE B N   1 
ATOM   4946  C CA  . ILE B 2 219 ? 99.016  68.862  100.391 1.00 347.21 ? 219 ILE B CA  1 
ATOM   4947  C C   . ILE B 2 219 ? 99.022  67.326  100.235 1.00 418.27 ? 219 ILE B C   1 
ATOM   4948  O O   . ILE B 2 219 ? 98.205  66.648  100.859 1.00 417.53 ? 219 ILE B O   1 
ATOM   4949  C CB  . ILE B 2 219 ? 97.924  69.565  99.545  1.00 363.55 ? 219 ILE B CB  1 
ATOM   4950  C CG1 . ILE B 2 219 ? 96.521  69.255  100.097 1.00 321.15 ? 219 ILE B CG1 1 
ATOM   4951  C CG2 . ILE B 2 219 ? 98.051  69.242  98.058  1.00 389.20 ? 219 ILE B CG2 1 
ATOM   4952  C CD1 . ILE B 2 219 ? 95.384  70.074  99.515  1.00 278.04 ? 219 ILE B CD1 1 
ATOM   4953  N N   . GLY B 2 220 ? 99.941  66.765  99.424  1.00 451.33 ? 220 GLY B N   1 
ATOM   4954  C CA  . GLY B 2 220 ? 100.179 65.325  99.349  1.00 423.86 ? 220 GLY B CA  1 
ATOM   4955  C C   . GLY B 2 220 ? 100.772 64.718  100.626 1.00 401.66 ? 220 GLY B C   1 
ATOM   4956  O O   . GLY B 2 220 ? 100.364 63.623  101.025 1.00 265.32 ? 220 GLY B O   1 
ATOM   4957  N N   . LYS B 2 221 ? 101.729 65.432  101.250 1.00 472.43 ? 221 LYS B N   1 
ATOM   4958  C CA  . LYS B 2 221 ? 102.342 65.037  102.518 1.00 462.29 ? 221 LYS B CA  1 
ATOM   4959  C C   . LYS B 2 221 ? 101.396 65.212  103.717 1.00 433.56 ? 221 LYS B C   1 
ATOM   4960  O O   . LYS B 2 221 ? 101.475 64.437  104.672 1.00 364.91 ? 221 LYS B O   1 
ATOM   4961  C CB  . LYS B 2 221 ? 103.621 65.847  102.757 1.00 458.30 ? 221 LYS B CB  1 
ATOM   4962  C CG  . LYS B 2 221 ? 104.808 65.485  101.869 1.00 414.04 ? 221 LYS B CG  1 
ATOM   4963  C CD  . LYS B 2 221 ? 105.900 66.549  101.831 1.00 457.65 ? 221 LYS B CD  1 
ATOM   4964  C CE  . LYS B 2 221 ? 106.481 66.927  103.181 1.00 484.66 ? 221 LYS B CE  1 
ATOM   4965  N NZ  . LYS B 2 221 ? 107.417 68.074  103.074 1.00 481.99 ? 221 LYS B NZ  1 
ATOM   4966  N N   . GLY B 2 222 ? 100.520 66.230  103.684 1.00 410.82 ? 222 GLY B N   1 
ATOM   4967  C CA  . GLY B 2 222 ? 99.509  66.441  104.715 1.00 326.53 ? 222 GLY B CA  1 
ATOM   4968  C C   . GLY B 2 222 ? 100.091 66.949  106.022 1.00 271.70 ? 222 GLY B C   1 
ATOM   4969  O O   . GLY B 2 222 ? 100.972 67.822  105.952 1.00 259.34 ? 222 GLY B O   1 
ATOM   4970  N N   . PHE B 2 233 ? 86.456  77.236  108.589 1.00 414.35 ? 233 PHE B N   1 
ATOM   4971  C CA  . PHE B 2 233 ? 87.398  77.462  107.455 1.00 404.54 ? 233 PHE B CA  1 
ATOM   4972  C C   . PHE B 2 233 ? 87.168  78.807  106.743 1.00 388.57 ? 233 PHE B C   1 
ATOM   4973  O O   . PHE B 2 233 ? 88.096  79.305  106.108 1.00 364.70 ? 233 PHE B O   1 
ATOM   4974  C CB  . PHE B 2 233 ? 87.313  76.292  106.463 1.00 357.19 ? 233 PHE B CB  1 
ATOM   4975  C CG  . PHE B 2 233 ? 88.352  76.318  105.366 1.00 354.86 ? 233 PHE B CG  1 
ATOM   4976  C CD1 . PHE B 2 233 ? 89.704  76.213  105.675 1.00 338.17 ? 233 PHE B CD1 1 
ATOM   4977  C CD2 . PHE B 2 233 ? 87.990  76.462  104.028 1.00 359.96 ? 233 PHE B CD2 1 
ATOM   4978  C CE1 . PHE B 2 233 ? 90.673  76.238  104.677 1.00 340.77 ? 233 PHE B CE1 1 
ATOM   4979  C CE2 . PHE B 2 233 ? 88.962  76.488  103.031 1.00 364.51 ? 233 PHE B CE2 1 
ATOM   4980  C CZ  . PHE B 2 233 ? 90.303  76.383  103.354 1.00 358.29 ? 233 PHE B CZ  1 
ATOM   4981  N N   . GLU B 2 234 ? 85.962  79.409  106.831 1.00 358.18 ? 234 GLU B N   1 
ATOM   4982  C CA  . GLU B 2 234 ? 85.581  80.537  105.980 1.00 279.61 ? 234 GLU B CA  1 
ATOM   4983  C C   . GLU B 2 234 ? 84.951  81.693  106.780 1.00 262.48 ? 234 GLU B C   1 
ATOM   4984  O O   . GLU B 2 234 ? 83.963  82.279  106.328 1.00 282.95 ? 234 GLU B O   1 
ATOM   4985  C CB  . GLU B 2 234 ? 84.613  80.064  104.883 1.00 310.87 ? 234 GLU B CB  1 
ATOM   4986  C CG  . GLU B 2 234 ? 85.104  78.894  104.040 1.00 340.89 ? 234 GLU B CG  1 
ATOM   4987  C CD  . GLU B 2 234 ? 84.247  78.532  102.826 1.00 322.32 ? 234 GLU B CD  1 
ATOM   4988  O OE1 . GLU B 2 234 ? 83.440  79.377  102.324 1.00 226.30 ? 234 GLU B OE1 1 
ATOM   4989  O OE2 . GLU B 2 234 ? 84.386  77.381  102.370 1.00 298.77 ? 234 GLU B OE2 1 
ATOM   4990  N N   . GLY B 2 235 ? 85.511  82.052  107.953 1.00 258.63 ? 235 GLY B N   1 
ATOM   4991  C CA  . GLY B 2 235 ? 85.078  83.238  108.692 1.00 279.28 ? 235 GLY B CA  1 
ATOM   4992  C C   . GLY B 2 235 ? 85.281  84.530  107.887 1.00 337.23 ? 235 GLY B C   1 
ATOM   4993  O O   . GLY B 2 235 ? 86.413  84.989  107.757 1.00 391.15 ? 235 GLY B O   1 
ATOM   4994  N N   . THR B 2 236 ? 84.185  85.108  107.354 1.00 330.74 ? 236 THR B N   1 
ATOM   4995  C CA  . THR B 2 236 ? 84.212  86.020  106.208 1.00 281.79 ? 236 THR B CA  1 
ATOM   4996  C C   . THR B 2 236 ? 83.523  87.356  106.513 1.00 277.03 ? 236 THR B C   1 
ATOM   4997  O O   . THR B 2 236 ? 82.374  87.362  106.946 1.00 286.66 ? 236 THR B O   1 
ATOM   4998  C CB  . THR B 2 236 ? 83.545  85.350  104.994 1.00 273.43 ? 236 THR B CB  1 
ATOM   4999  O OG1 . THR B 2 236 ? 84.336  84.235  104.593 1.00 215.32 ? 236 THR B OG1 1 
ATOM   5000  C CG2 . THR B 2 236 ? 83.413  86.241  103.778 1.00 302.97 ? 236 THR B CG2 1 
ATOM   5001  N N   . LYS B 2 237 ? 84.222  88.482  106.259 1.00 386.21 ? 237 LYS B N   1 
ATOM   5002  C CA  . LYS B 2 237 ? 83.658  89.828  106.356 1.00 441.83 ? 237 LYS B CA  1 
ATOM   5003  C C   . LYS B 2 237 ? 82.874  90.164  105.077 1.00 415.04 ? 237 LYS B C   1 
ATOM   5004  O O   . LYS B 2 237 ? 83.287  91.004  104.267 1.00 301.55 ? 237 LYS B O   1 
ATOM   5005  C CB  . LYS B 2 237 ? 84.775  90.838  106.658 1.00 457.45 ? 237 LYS B CB  1 
ATOM   5006  C CG  . LYS B 2 237 ? 84.296  92.230  107.052 1.00 471.01 ? 237 LYS B CG  1 
ATOM   5007  C CD  . LYS B 2 237 ? 85.394  93.124  107.594 1.00 527.03 ? 237 LYS B CD  1 
ATOM   5008  C CE  . LYS B 2 237 ? 84.913  94.508  107.988 1.00 574.47 ? 237 LYS B CE  1 
ATOM   5009  N NZ  . LYS B 2 237 ? 84.539  95.339  106.818 1.00 595.30 ? 237 LYS B NZ  1 
ATOM   5010  N N   . LEU B 2 238 ? 81.717  89.496  104.914 1.00 421.39 ? 238 LEU B N   1 
ATOM   5011  C CA  . LEU B 2 238 ? 80.906  89.589  103.703 1.00 412.52 ? 238 LEU B CA  1 
ATOM   5012  C C   . LEU B 2 238 ? 80.169  90.931  103.687 1.00 409.98 ? 238 LEU B C   1 
ATOM   5013  O O   . LEU B 2 238 ? 79.287  91.166  104.511 1.00 405.45 ? 238 LEU B O   1 
ATOM   5014  C CB  . LEU B 2 238 ? 79.926  88.406  103.632 1.00 405.07 ? 238 LEU B CB  1 
ATOM   5015  C CG  . LEU B 2 238 ? 79.468  88.003  102.227 1.00 405.66 ? 238 LEU B CG  1 
ATOM   5016  C CD1 . LEU B 2 238 ? 78.706  86.682  102.260 1.00 372.43 ? 238 LEU B CD1 1 
ATOM   5017  C CD2 . LEU B 2 238 ? 78.620  89.090  101.569 1.00 398.91 ? 238 LEU B CD2 1 
ATOM   5018  N N   . ASP B 2 239 ? 80.543  91.799  102.734 1.00 415.13 ? 239 ASP B N   1 
ATOM   5019  C CA  . ASP B 2 239 ? 79.933  93.107  102.551 1.00 449.39 ? 239 ASP B CA  1 
ATOM   5020  C C   . ASP B 2 239 ? 80.117  93.540  101.095 1.00 507.75 ? 239 ASP B C   1 
ATOM   5021  O O   . ASP B 2 239 ? 81.250  93.595  100.620 1.00 595.93 ? 239 ASP B O   1 
ATOM   5022  C CB  . ASP B 2 239 ? 80.541  94.124  103.527 1.00 460.59 ? 239 ASP B CB  1 
ATOM   5023  C CG  . ASP B 2 239 ? 80.024  95.554  103.411 1.00 469.55 ? 239 ASP B CG  1 
ATOM   5024  O OD1 . ASP B 2 239 ? 79.056  95.787  102.653 1.00 473.88 ? 239 ASP B OD1 1 
ATOM   5025  O OD2 . ASP B 2 239 ? 80.597  96.435  104.083 1.00 439.62 ? 239 ASP B OD2 1 
ATOM   5026  N N   . VAL B 2 240 ? 79.009  93.870  100.405 1.00 468.90 ? 240 VAL B N   1 
ATOM   5027  C CA  . VAL B 2 240 ? 79.046  94.367  99.029  1.00 436.70 ? 240 VAL B CA  1 
ATOM   5028  C C   . VAL B 2 240 ? 79.895  95.649  98.948  1.00 429.63 ? 240 VAL B C   1 
ATOM   5029  O O   . VAL B 2 240 ? 80.542  95.885  97.930  1.00 413.87 ? 240 VAL B O   1 
ATOM   5030  C CB  . VAL B 2 240 ? 77.620  94.559  98.459  1.00 413.26 ? 240 VAL B CB  1 
ATOM   5031  C CG1 . VAL B 2 240 ? 77.611  95.224  97.082  1.00 412.33 ? 240 VAL B CG1 1 
ATOM   5032  C CG2 . VAL B 2 240 ? 76.857  93.238  98.407  1.00 409.57 ? 240 VAL B CG2 1 
ATOM   5033  N N   . GLY B 2 241 ? 79.918  96.466  100.015 1.00 444.88 ? 241 GLY B N   1 
ATOM   5034  C CA  . GLY B 2 241 ? 80.799  97.626  100.107 1.00 431.63 ? 241 GLY B CA  1 
ATOM   5035  C C   . GLY B 2 241 ? 82.290  97.343  100.346 1.00 418.01 ? 241 GLY B C   1 
ATOM   5036  O O   . GLY B 2 241 ? 83.058  98.304  100.415 1.00 371.69 ? 241 GLY B O   1 
ATOM   5037  N N   . ASN B 2 242 ? 82.706  96.065  100.472 1.00 422.25 ? 242 ASN B N   1 
ATOM   5038  C CA  . ASN B 2 242 ? 84.083  95.678  100.786 1.00 384.85 ? 242 ASN B CA  1 
ATOM   5039  C C   . ASN B 2 242 ? 84.624  94.621  99.806  1.00 357.12 ? 242 ASN B C   1 
ATOM   5040  O O   . ASN B 2 242 ? 85.774  94.753  99.395  1.00 373.57 ? 242 ASN B O   1 
ATOM   5041  C CB  . ASN B 2 242 ? 84.187  95.221  102.248 1.00 400.28 ? 242 ASN B CB  1 
ATOM   5042  C CG  . ASN B 2 242 ? 85.575  95.269  102.864 1.00 389.18 ? 242 ASN B CG  1 
ATOM   5043  O OD1 . ASN B 2 242 ? 85.699  95.189  104.081 1.00 420.18 ? 242 ASN B OD1 1 
ATOM   5044  N ND2 . ASN B 2 242 ? 86.632  95.396  102.077 1.00 368.09 ? 242 ASN B ND2 1 
ATOM   5045  N N   . ILE B 2 243 ? 83.831  93.591  99.440  1.00 336.51 ? 243 ILE B N   1 
ATOM   5046  C CA  . ILE B 2 243 ? 84.200  92.559  98.464  1.00 294.50 ? 243 ILE B CA  1 
ATOM   5047  C C   . ILE B 2 243 ? 84.608  93.157  97.110  1.00 271.47 ? 243 ILE B C   1 
ATOM   5048  O O   . ILE B 2 243 ? 85.435  92.577  96.406  1.00 310.13 ? 243 ILE B O   1 
ATOM   5049  C CB  . ILE B 2 243 ? 83.050  91.537  98.302  1.00 318.73 ? 243 ILE B CB  1 
ATOM   5050  C CG1 . ILE B 2 243 ? 83.506  90.258  97.590  1.00 295.08 ? 243 ILE B CG1 1 
ATOM   5051  C CG2 . ILE B 2 243 ? 81.831  92.155  97.617  1.00 348.53 ? 243 ILE B CG2 1 
ATOM   5052  C CD1 . ILE B 2 243 ? 82.427  89.203  97.468  1.00 285.44 ? 243 ILE B CD1 1 
ATOM   5053  N N   . VAL B 2 244 ? 84.034  94.310  96.747  1.00 277.12 ? 244 VAL B N   1 
ATOM   5054  C CA  . VAL B 2 244 ? 84.407  95.074  95.561  1.00 308.38 ? 244 VAL B CA  1 
ATOM   5055  C C   . VAL B 2 244 ? 85.895  95.445  95.557  1.00 337.46 ? 244 VAL B C   1 
ATOM   5056  O O   . VAL B 2 244 ? 86.521  95.421  94.501  1.00 370.98 ? 244 VAL B O   1 
ATOM   5057  C CB  . VAL B 2 244 ? 83.498  96.315  95.450  1.00 331.89 ? 244 VAL B CB  1 
ATOM   5058  C CG1 . VAL B 2 244 ? 84.008  97.377  94.476  1.00 306.55 ? 244 VAL B CG1 1 
ATOM   5059  C CG2 . VAL B 2 244 ? 82.087  95.879  95.089  1.00 356.53 ? 244 VAL B CG2 1 
ATOM   5060  N N   . LEU B 2 245 ? 86.467  95.793  96.716  1.00 282.19 ? 245 LEU B N   1 
ATOM   5061  C CA  . LEU B 2 245 ? 87.888  96.116  96.793  1.00 205.66 ? 245 LEU B CA  1 
ATOM   5062  C C   . LEU B 2 245 ? 88.743  94.834  96.778  1.00 256.10 ? 245 LEU B C   1 
ATOM   5063  O O   . LEU B 2 245 ? 89.920  94.919  96.436  1.00 231.27 ? 245 LEU B O   1 
ATOM   5064  C CB  . LEU B 2 245 ? 88.133  96.984  98.033  1.00 289.18 ? 245 LEU B CB  1 
ATOM   5065  C CG  . LEU B 2 245 ? 87.780  98.466  97.855  1.00 335.95 ? 245 LEU B CG  1 
ATOM   5066  C CD1 . LEU B 2 245 ? 86.273  98.705  97.753  1.00 315.17 ? 245 LEU B CD1 1 
ATOM   5067  C CD2 . LEU B 2 245 ? 88.365  99.291  98.994  1.00 385.85 ? 245 LEU B CD2 1 
ATOM   5068  N N   . ALA B 2 246 ? 88.184  93.653  97.127  1.00 318.33 ? 246 ALA B N   1 
ATOM   5069  C CA  . ALA B 2 246 ? 88.813  92.365  96.816  1.00 283.13 ? 246 ALA B CA  1 
ATOM   5070  C C   . ALA B 2 246 ? 88.929  92.202  95.301  1.00 264.19 ? 246 ALA B C   1 
ATOM   5071  O O   . ALA B 2 246 ? 90.016  91.937  94.798  1.00 291.46 ? 246 ALA B O   1 
ATOM   5072  C CB  . ALA B 2 246 ? 88.066  91.198  97.435  1.00 277.07 ? 246 ALA B CB  1 
ATOM   5073  N N   . LEU B 2 247 ? 87.812  92.393  94.585  1.00 246.27 ? 247 LEU B N   1 
ATOM   5074  C CA  . LEU B 2 247 ? 87.787  92.312  93.131  1.00 221.12 ? 247 LEU B CA  1 
ATOM   5075  C C   . LEU B 2 247 ? 88.731  93.344  92.490  1.00 205.64 ? 247 LEU B C   1 
ATOM   5076  O O   . LEU B 2 247 ? 89.530  92.966  91.649  1.00 221.67 ? 247 LEU B O   1 
ATOM   5077  C CB  . LEU B 2 247 ? 86.344  92.479  92.641  1.00 279.19 ? 247 LEU B CB  1 
ATOM   5078  C CG  . LEU B 2 247 ? 85.394  91.336  93.001  1.00 383.43 ? 247 LEU B CG  1 
ATOM   5079  C CD1 . LEU B 2 247 ? 83.949  91.725  92.734  1.00 438.55 ? 247 LEU B CD1 1 
ATOM   5080  C CD2 . LEU B 2 247 ? 85.735  90.068  92.232  1.00 405.23 ? 247 LEU B CD2 1 
ATOM   5081  N N   . TYR B 2 248 ? 88.678  94.626  92.867  1.00 205.98 ? 248 TYR B N   1 
ATOM   5082  C CA  . TYR B 2 248 ? 89.613  95.644  92.366  1.00 216.08 ? 248 TYR B CA  1 
ATOM   5083  C C   . TYR B 2 248 ? 91.091  95.306  92.638  1.00 198.87 ? 248 TYR B C   1 
ATOM   5084  O O   . TYR B 2 248 ? 91.954  95.678  91.841  1.00 196.54 ? 248 TYR B O   1 
ATOM   5085  C CB  . TYR B 2 248 ? 89.175  97.023  92.899  1.00 231.01 ? 248 TYR B CB  1 
ATOM   5086  C CG  . TYR B 2 248 ? 88.261  97.825  91.971  1.00 253.80 ? 248 TYR B CG  1 
ATOM   5087  C CD1 . TYR B 2 248 ? 87.554  97.233  90.908  1.00 293.60 ? 248 TYR B CD1 1 
ATOM   5088  C CD2 . TYR B 2 248 ? 88.112  99.203  92.138  1.00 208.32 ? 248 TYR B CD2 1 
ATOM   5089  C CE1 . TYR B 2 248 ? 86.738  97.968  90.059  1.00 271.75 ? 248 TYR B CE1 1 
ATOM   5090  C CE2 . TYR B 2 248 ? 87.294  99.947  91.293  1.00 284.05 ? 248 TYR B CE2 1 
ATOM   5091  C CZ  . TYR B 2 248 ? 86.607  99.332  90.249  1.00 281.74 ? 248 TYR B CZ  1 
ATOM   5092  O OH  . TYR B 2 248 ? 85.791  100.026 89.397  1.00 266.53 ? 248 TYR B OH  1 
ATOM   5093  N N   . SER B 2 249 ? 91.382  94.600  93.738  1.00 242.49 ? 249 SER B N   1 
ATOM   5094  C CA  . SER B 2 249 ? 92.717  94.082  94.012  1.00 235.05 ? 249 SER B CA  1 
ATOM   5095  C C   . SER B 2 249 ? 93.058  92.912  93.080  1.00 202.89 ? 249 SER B C   1 
ATOM   5096  O O   . SER B 2 249 ? 94.155  92.866  92.534  1.00 199.41 ? 249 SER B O   1 
ATOM   5097  C CB  . SER B 2 249 ? 92.864  93.692  95.471  1.00 267.72 ? 249 SER B CB  1 
ATOM   5098  O OG  . SER B 2 249 ? 92.657  94.821  96.309  1.00 276.08 ? 249 SER B OG  1 
ATOM   5099  N N   . GLY B 2 250 ? 92.126  91.969  92.900  1.00 206.01 ? 250 GLY B N   1 
ATOM   5100  C CA  . GLY B 2 250 ? 92.325  90.828  92.022  1.00 197.90 ? 250 GLY B CA  1 
ATOM   5101  C C   . GLY B 2 250 ? 92.478  91.233  90.556  1.00 182.53 ? 250 GLY B C   1 
ATOM   5102  O O   . GLY B 2 250 ? 93.382  90.763  89.890  1.00 183.22 ? 250 GLY B O   1 
ATOM   5103  N N   . LEU B 2 251 ? 91.606  92.103  90.043  1.00 196.96 ? 251 LEU B N   1 
ATOM   5104  C CA  . LEU B 2 251 ? 91.625  92.458  88.631  1.00 227.23 ? 251 LEU B CA  1 
ATOM   5105  C C   . LEU B 2 251 ? 92.949  93.109  88.236  1.00 187.46 ? 251 LEU B C   1 
ATOM   5106  O O   . LEU B 2 251 ? 93.371  92.914  87.100  1.00 226.05 ? 251 LEU B O   1 
ATOM   5107  C CB  . LEU B 2 251 ? 90.441  93.382  88.324  1.00 240.89 ? 251 LEU B CB  1 
ATOM   5108  C CG  . LEU B 2 251 ? 89.069  92.715  88.242  1.00 249.85 ? 251 LEU B CG  1 
ATOM   5109  C CD1 . LEU B 2 251 ? 87.968  93.760  88.178  1.00 242.27 ? 251 LEU B CD1 1 
ATOM   5110  C CD2 . LEU B 2 251 ? 88.959  91.792  87.039  1.00 240.69 ? 251 LEU B CD2 1 
ATOM   5111  N N   . PHE B 2 252 ? 93.600  93.862  89.139  1.00 175.94 ? 252 PHE B N   1 
ATOM   5112  C CA  . PHE B 2 252 ? 94.909  94.430  88.833  1.00 170.79 ? 252 PHE B CA  1 
ATOM   5113  C C   . PHE B 2 252 ? 95.881  93.325  88.419  1.00 134.77 ? 252 PHE B C   1 
ATOM   5114  O O   . PHE B 2 252 ? 96.759  93.576  87.597  1.00 190.73 ? 252 PHE B O   1 
ATOM   5115  C CB  . PHE B 2 252 ? 95.527  95.218  89.998  1.00 213.03 ? 252 PHE B CB  1 
ATOM   5116  C CG  . PHE B 2 252 ? 97.009  95.502  89.816  1.00 191.09 ? 252 PHE B CG  1 
ATOM   5117  C CD1 . PHE B 2 252 ? 97.415  96.473  88.909  1.00 176.01 ? 252 PHE B CD1 1 
ATOM   5118  C CD2 . PHE B 2 252 ? 98.005  94.791  90.517  1.00 205.22 ? 252 PHE B CD2 1 
ATOM   5119  C CE1 . PHE B 2 252 ? 98.769  96.741  88.721  1.00 198.18 ? 252 PHE B CE1 1 
ATOM   5120  C CE2 . PHE B 2 252 ? 99.351  95.058  90.316  1.00 188.14 ? 252 PHE B CE2 1 
ATOM   5121  C CZ  . PHE B 2 252 ? 99.733  96.033  89.419  1.00 193.29 ? 252 PHE B CZ  1 
ATOM   5122  N N   . ALA B 2 253 ? 95.743  92.113  88.964  1.00 132.95 ? 253 ALA B N   1 
ATOM   5123  C CA  . ALA B 2 253 ? 96.660  91.033  88.634  1.00 187.86 ? 253 ALA B CA  1 
ATOM   5124  C C   . ALA B 2 253 ? 96.326  90.403  87.282  1.00 152.70 ? 253 ALA B C   1 
ATOM   5125  O O   . ALA B 2 253 ? 97.199  89.788  86.689  1.00 126.07 ? 253 ALA B O   1 
ATOM   5126  C CB  . ALA B 2 253 ? 96.665  90.018  89.737  1.00 217.12 ? 253 ALA B CB  1 
ATOM   5127  N N   . TYR B 2 254 ? 95.090  90.565  86.798  1.00 167.91 ? 254 TYR B N   1 
ATOM   5128  C CA  . TYR B 2 254 ? 94.720  90.196  85.436  1.00 179.10 ? 254 TYR B CA  1 
ATOM   5129  C C   . TYR B 2 254 ? 94.899  91.304  84.402  1.00 158.86 ? 254 TYR B C   1 
ATOM   5130  O O   . TYR B 2 254 ? 94.645  91.050  83.232  1.00 183.97 ? 254 TYR B O   1 
ATOM   5131  C CB  . TYR B 2 254 ? 93.244  89.795  85.451  1.00 167.38 ? 254 TYR B CB  1 
ATOM   5132  C CG  . TYR B 2 254 ? 93.041  88.398  85.999  1.00 195.94 ? 254 TYR B CG  1 
ATOM   5133  C CD1 . TYR B 2 254 ? 93.242  87.271  85.194  1.00 195.81 ? 254 TYR B CD1 1 
ATOM   5134  C CD2 . TYR B 2 254 ? 92.660  88.217  87.317  1.00 194.34 ? 254 TYR B CD2 1 
ATOM   5135  C CE1 . TYR B 2 254 ? 93.062  85.991  85.689  1.00 180.65 ? 254 TYR B CE1 1 
ATOM   5136  C CE2 . TYR B 2 254 ? 92.474  86.943  87.819  1.00 223.83 ? 254 TYR B CE2 1 
ATOM   5137  C CZ  . TYR B 2 254 ? 92.671  85.836  87.005  1.00 221.03 ? 254 TYR B CZ  1 
ATOM   5138  O OH  . TYR B 2 254 ? 92.474  84.602  87.534  1.00 296.74 ? 254 TYR B OH  1 
ATOM   5139  N N   . GLY B 2 255 ? 95.301  92.516  84.799  1.00 139.41 ? 255 GLY B N   1 
ATOM   5140  C CA  . GLY B 2 255 ? 95.343  93.646  83.883  1.00 158.03 ? 255 GLY B CA  1 
ATOM   5141  C C   . GLY B 2 255 ? 96.334  93.356  82.764  1.00 197.02 ? 255 GLY B C   1 
ATOM   5142  O O   . GLY B 2 255 ? 97.476  93.026  83.057  1.00 188.65 ? 255 GLY B O   1 
ATOM   5143  N N   . GLY B 2 256 ? 95.881  93.459  81.507  1.00 203.84 ? 256 GLY B N   1 
ATOM   5144  C CA  . GLY B 2 256 ? 96.731  93.160  80.368  1.00 183.64 ? 256 GLY B CA  1 
ATOM   5145  C C   . GLY B 2 256 ? 96.100  92.290  79.283  1.00 194.72 ? 256 GLY B C   1 
ATOM   5146  O O   . GLY B 2 256 ? 96.723  92.123  78.239  1.00 217.43 ? 256 GLY B O   1 
ATOM   5147  N N   . TRP B 2 257 ? 94.895  91.740  79.489  1.00 194.43 ? 257 TRP B N   1 
ATOM   5148  C CA  . TRP B 2 257 ? 94.265  90.945  78.447  1.00 184.84 ? 257 TRP B CA  1 
ATOM   5149  C C   . TRP B 2 257 ? 94.049  91.773  77.177  1.00 198.87 ? 257 TRP B C   1 
ATOM   5150  O O   . TRP B 2 257 ? 94.041  91.220  76.072  1.00 220.22 ? 257 TRP B O   1 
ATOM   5151  C CB  . TRP B 2 257 ? 92.958  90.331  78.976  1.00 167.74 ? 257 TRP B CB  1 
ATOM   5152  C CG  . TRP B 2 257 ? 91.789  91.266  79.121  1.00 187.07 ? 257 TRP B CG  1 
ATOM   5153  C CD1 . TRP B 2 257 ? 91.017  91.826  78.145  1.00 245.94 ? 257 TRP B CD1 1 
ATOM   5154  C CD2 . TRP B 2 257 ? 91.225  91.721  80.354  1.00 155.03 ? 257 TRP B CD2 1 
ATOM   5155  N NE1 . TRP B 2 257 ? 90.038  92.624  78.669  1.00 200.39 ? 257 TRP B NE1 1 
ATOM   5156  C CE2 . TRP B 2 257 ? 90.138  92.564  80.030  1.00 194.55 ? 257 TRP B CE2 1 
ATOM   5157  C CE3 . TRP B 2 257 ? 91.529  91.492  81.696  1.00 211.89 ? 257 TRP B CE3 1 
ATOM   5158  C CZ2 . TRP B 2 257 ? 89.361  93.176  81.010  1.00 254.67 ? 257 TRP B CZ2 1 
ATOM   5159  C CZ3 . TRP B 2 257 ? 90.753  92.090  82.666  1.00 270.49 ? 257 TRP B CZ3 1 
ATOM   5160  C CH2 . TRP B 2 257 ? 89.679  92.921  82.327  1.00 254.71 ? 257 TRP B CH2 1 
ATOM   5161  N N   . ASN B 2 258 ? 93.854  93.096  77.350  1.00 186.48 ? 258 ASN B N   1 
ATOM   5162  C CA  . ASN B 2 258 ? 93.616  94.007  76.239  1.00 201.38 ? 258 ASN B CA  1 
ATOM   5163  C C   . ASN B 2 258 ? 94.913  94.429  75.559  1.00 176.60 ? 258 ASN B C   1 
ATOM   5164  O O   . ASN B 2 258 ? 94.847  95.189  74.596  1.00 213.09 ? 258 ASN B O   1 
ATOM   5165  C CB  . ASN B 2 258 ? 92.779  95.227  76.662  1.00 215.20 ? 258 ASN B CB  1 
ATOM   5166  C CG  . ASN B 2 258 ? 93.275  95.976  77.877  1.00 198.82 ? 258 ASN B CG  1 
ATOM   5167  O OD1 . ASN B 2 258 ? 94.072  95.476  78.656  1.00 166.92 ? 258 ASN B OD1 1 
ATOM   5168  N ND2 . ASN B 2 258 ? 92.809  97.200  78.042  1.00 230.90 ? 258 ASN B ND2 1 
ATOM   5169  N N   . TYR B 2 259 ? 96.083  93.968  76.017  1.00 171.13 ? 259 TYR B N   1 
ATOM   5170  C CA  . TYR B 2 259 ? 97.334  94.525  75.515  1.00 184.41 ? 259 TYR B CA  1 
ATOM   5171  C C   . TYR B 2 259 ? 97.654  94.015  74.111  1.00 204.29 ? 259 TYR B C   1 
ATOM   5172  O O   . TYR B 2 259 ? 98.262  94.792  73.363  1.00 204.93 ? 259 TYR B O   1 
ATOM   5173  C CB  . TYR B 2 259 ? 98.488  94.304  76.496  1.00 206.85 ? 259 TYR B CB  1 
ATOM   5174  C CG  . TYR B 2 259 ? 98.549  95.264  77.684  1.00 191.92 ? 259 TYR B CG  1 
ATOM   5175  C CD1 . TYR B 2 259 ? 97.495  96.123  78.023  1.00 226.49 ? 259 TYR B CD1 1 
ATOM   5176  C CD2 . TYR B 2 259 ? 99.686  95.290  78.490  1.00 169.27 ? 259 TYR B CD2 1 
ATOM   5177  C CE1 . TYR B 2 259 ? 97.574  96.984  79.105  1.00 238.46 ? 259 TYR B CE1 1 
ATOM   5178  C CE2 . TYR B 2 259 ? 99.774  96.137  79.582  1.00 191.65 ? 259 TYR B CE2 1 
ATOM   5179  C CZ  . TYR B 2 259 ? 98.715  96.986  79.884  1.00 243.85 ? 259 TYR B CZ  1 
ATOM   5180  O OH  . TYR B 2 259 ? 98.753  97.839  80.941  1.00 295.26 ? 259 TYR B OH  1 
ATOM   5181  N N   . LEU B 2 260 ? 97.256  92.778  73.736  1.00 181.17 ? 260 LEU B N   1 
ATOM   5182  C CA  . LEU B 2 260 ? 97.537  92.310  72.376  1.00 173.75 ? 260 LEU B CA  1 
ATOM   5183  C C   . LEU B 2 260 ? 96.756  93.086  71.314  1.00 156.15 ? 260 LEU B C   1 
ATOM   5184  O O   . LEU B 2 260 ? 97.216  93.213  70.175  1.00 119.51 ? 260 LEU B O   1 
ATOM   5185  C CB  . LEU B 2 260 ? 97.262  90.822  72.221  1.00 185.10 ? 260 LEU B CB  1 
ATOM   5186  C CG  . LEU B 2 260 ? 98.001  90.174  71.043  1.00 207.69 ? 260 LEU B CG  1 
ATOM   5187  C CD1 . LEU B 2 260 ? 99.526  90.167  71.254  1.00 161.01 ? 260 LEU B CD1 1 
ATOM   5188  C CD2 . LEU B 2 260 ? 97.489  88.764  70.798  1.00 218.27 ? 260 LEU B CD2 1 
ATOM   5189  N N   . ASN B 2 261 ? 95.605  93.636  71.687  1.00 163.73 ? 261 ASN B N   1 
ATOM   5190  C CA  . ASN B 2 261 ? 94.873  94.556  70.818  1.00 192.73 ? 261 ASN B CA  1 
ATOM   5191  C C   . ASN B 2 261 ? 95.631  95.841  70.432  1.00 179.25 ? 261 ASN B C   1 
ATOM   5192  O O   . ASN B 2 261 ? 95.194  96.513  69.502  1.00 156.40 ? 261 ASN B O   1 
ATOM   5193  C CB  . ASN B 2 261 ? 93.508  94.877  71.433  1.00 209.52 ? 261 ASN B CB  1 
ATOM   5194  C CG  . ASN B 2 261 ? 92.496  93.847  71.002  1.00 233.49 ? 261 ASN B CG  1 
ATOM   5195  O OD1 . ASN B 2 261 ? 91.871  94.018  69.960  1.00 234.46 ? 261 ASN B OD1 1 
ATOM   5196  N ND2 . ASN B 2 261 ? 92.343  92.782  71.772  1.00 263.47 ? 261 ASN B ND2 1 
ATOM   5197  N N   . PHE B 2 262 ? 96.743  96.203  71.090  1.00 160.87 ? 262 PHE B N   1 
ATOM   5198  C CA  . PHE B 2 262 ? 97.557  97.315  70.627  1.00 157.15 ? 262 PHE B CA  1 
ATOM   5199  C C   . PHE B 2 262 ? 98.532  96.935  69.507  1.00 167.91 ? 262 PHE B C   1 
ATOM   5200  O O   . PHE B 2 262 ? 99.127  97.862  68.946  1.00 192.63 ? 262 PHE B O   1 
ATOM   5201  C CB  . PHE B 2 262 ? 98.342  97.919  71.789  1.00 189.79 ? 262 PHE B CB  1 
ATOM   5202  C CG  . PHE B 2 262 ? 97.474  98.488  72.870  1.00 189.05 ? 262 PHE B CG  1 
ATOM   5203  C CD1 . PHE B 2 262 ? 96.625  99.538  72.587  1.00 179.14 ? 262 PHE B CD1 1 
ATOM   5204  C CD2 . PHE B 2 262 ? 97.511  97.985  74.164  1.00 227.54 ? 262 PHE B CD2 1 
ATOM   5205  C CE1 . PHE B 2 262 ? 95.810  100.070 73.577  1.00 246.59 ? 262 PHE B CE1 1 
ATOM   5206  C CE2 . PHE B 2 262 ? 96.697  98.519  75.154  1.00 239.93 ? 262 PHE B CE2 1 
ATOM   5207  C CZ  . PHE B 2 262 ? 95.849  99.562  74.861  1.00 251.09 ? 262 PHE B CZ  1 
ATOM   5208  N N   . VAL B 2 263 ? 98.712  95.639  69.168  1.00 140.74 ? 263 VAL B N   1 
ATOM   5209  C CA  . VAL B 2 263 ? 99.690  95.251  68.151  1.00 196.79 ? 263 VAL B CA  1 
ATOM   5210  C C   . VAL B 2 263 ? 99.099  94.429  66.986  1.00 254.41 ? 263 VAL B C   1 
ATOM   5211  O O   . VAL B 2 263 ? 99.809  93.648  66.337  1.00 260.27 ? 263 VAL B O   1 
ATOM   5212  C CB  . VAL B 2 263 ? 100.857 94.517  68.842  1.00 209.11 ? 263 VAL B CB  1 
ATOM   5213  C CG1 . VAL B 2 263 ? 101.539 95.442  69.843  1.00 206.33 ? 263 VAL B CG1 1 
ATOM   5214  C CG2 . VAL B 2 263 ? 100.453 93.188  69.488  1.00 172.57 ? 263 VAL B CG2 1 
ATOM   5215  N N   . THR B 2 264 ? 97.811  94.623  66.684  1.00 261.03 ? 264 THR B N   1 
ATOM   5216  C CA  . THR B 2 264 ? 97.120  93.894  65.630  1.00 231.23 ? 264 THR B CA  1 
ATOM   5217  C C   . THR B 2 264 ? 97.713  94.175  64.247  1.00 223.87 ? 264 THR B C   1 
ATOM   5218  O O   . THR B 2 264 ? 97.690  93.286  63.381  1.00 246.47 ? 264 THR B O   1 
ATOM   5219  C CB  . THR B 2 264 ? 95.620  94.229  65.680  1.00 235.08 ? 264 THR B CB  1 
ATOM   5220  O OG1 . THR B 2 264 ? 95.471  95.645  65.715  1.00 178.96 ? 264 THR B OG1 1 
ATOM   5221  C CG2 . THR B 2 264 ? 94.912  93.671  66.894  1.00 204.99 ? 264 THR B CG2 1 
ATOM   5222  N N   . GLU B 2 265 ? 98.236  95.403  64.047  1.00 227.36 ? 265 GLU B N   1 
ATOM   5223  C CA  . GLU B 2 265 ? 98.895  95.793  62.804  1.00 269.11 ? 265 GLU B CA  1 
ATOM   5224  C C   . GLU B 2 265 ? 100.361 95.354  62.775  1.00 232.76 ? 265 GLU B C   1 
ATOM   5225  O O   . GLU B 2 265 ? 101.106 95.803  61.897  1.00 243.46 ? 265 GLU B O   1 
ATOM   5226  C CB  . GLU B 2 265 ? 98.796  97.302  62.571  1.00 289.92 ? 265 GLU B CB  1 
ATOM   5227  C CG  . GLU B 2 265 ? 97.409  97.758  62.182  1.00 349.89 ? 265 GLU B CG  1 
ATOM   5228  C CD  . GLU B 2 265 ? 97.344  99.262  61.960  1.00 415.33 ? 265 GLU B CD  1 
ATOM   5229  O OE1 . GLU B 2 265 ? 97.874  99.743  60.938  1.00 477.03 ? 265 GLU B OE1 1 
ATOM   5230  O OE2 . GLU B 2 265 ? 96.773  99.956  62.819  1.00 443.14 ? 265 GLU B OE2 1 
ATOM   5231  N N   . GLU B 2 266 ? 100.774 94.482  63.710  1.00 195.15 ? 266 GLU B N   1 
ATOM   5232  C CA  . GLU B 2 266 ? 102.147 93.997  63.781  1.00 238.76 ? 266 GLU B CA  1 
ATOM   5233  C C   . GLU B 2 266 ? 102.225 92.457  63.888  1.00 242.04 ? 266 GLU B C   1 
ATOM   5234  O O   . GLU B 2 266 ? 103.323 91.907  63.757  1.00 190.54 ? 266 GLU B O   1 
ATOM   5235  C CB  . GLU B 2 266 ? 102.790 94.811  64.913  1.00 272.54 ? 266 GLU B CB  1 
ATOM   5236  C CG  . GLU B 2 266 ? 104.317 94.815  64.917  1.00 308.78 ? 266 GLU B CG  1 
ATOM   5237  C CD  . GLU B 2 266 ? 105.001 95.960  65.666  1.00 331.66 ? 266 GLU B CD  1 
ATOM   5238  O OE1 . GLU B 2 266 ? 104.307 96.831  66.225  1.00 321.23 ? 266 GLU B OE1 1 
ATOM   5239  O OE2 . GLU B 2 266 ? 106.246 95.989  65.694  1.00 334.42 ? 266 GLU B OE2 1 
ATOM   5240  N N   . MET B 2 267 ? 101.093 91.755  64.099  1.00 224.37 ? 267 MET B N   1 
ATOM   5241  C CA  . MET B 2 267 ? 101.006 90.305  63.979  1.00 250.56 ? 267 MET B CA  1 
ATOM   5242  C C   . MET B 2 267 ? 100.977 89.828  62.523  1.00 248.26 ? 267 MET B C   1 
ATOM   5243  O O   . MET B 2 267 ? 100.453 90.520  61.658  1.00 266.20 ? 267 MET B O   1 
ATOM   5244  C CB  . MET B 2 267 ? 99.745  89.813  64.695  1.00 260.27 ? 267 MET B CB  1 
ATOM   5245  C CG  . MET B 2 267 ? 99.965  89.635  66.169  1.00 270.89 ? 267 MET B CG  1 
ATOM   5246  S SD  . MET B 2 267 ? 98.507  89.009  67.012  1.00 258.80 ? 267 MET B SD  1 
ATOM   5247  C CE  . MET B 2 267 ? 97.512  90.499  67.039  1.00 190.49 ? 267 MET B CE  1 
ATOM   5248  N N   . ILE B 2 268 ? 101.522 88.629  62.258  1.00 222.23 ? 268 ILE B N   1 
ATOM   5249  C CA  . ILE B 2 268 ? 101.688 88.136  60.891  1.00 275.78 ? 268 ILE B CA  1 
ATOM   5250  C C   . ILE B 2 268 ? 100.361 87.703  60.251  1.00 282.71 ? 268 ILE B C   1 
ATOM   5251  O O   . ILE B 2 268 ? 100.275 87.681  59.022  1.00 315.75 ? 268 ILE B O   1 
ATOM   5252  C CB  . ILE B 2 268 ? 102.722 86.987  60.810  1.00 322.73 ? 268 ILE B CB  1 
ATOM   5253  C CG1 . ILE B 2 268 ? 102.294 85.701  61.537  1.00 368.09 ? 268 ILE B CG1 1 
ATOM   5254  C CG2 . ILE B 2 268 ? 104.087 87.465  61.285  1.00 279.66 ? 268 ILE B CG2 1 
ATOM   5255  C CD1 . ILE B 2 268 ? 102.973 84.445  61.006  1.00 342.13 ? 268 ILE B CD1 1 
ATOM   5256  N N   . ASN B 2 269 ? 99.339  87.345  61.053  1.00 272.83 ? 269 ASN B N   1 
ATOM   5257  C CA  . ASN B 2 269 ? 98.064  86.864  60.526  1.00 274.68 ? 269 ASN B CA  1 
ATOM   5258  C C   . ASN B 2 269 ? 96.949  87.195  61.523  1.00 213.42 ? 269 ASN B C   1 
ATOM   5259  O O   . ASN B 2 269 ? 96.514  86.322  62.274  1.00 174.29 ? 269 ASN B O   1 
ATOM   5260  C CB  . ASN B 2 269 ? 98.153  85.371  60.186  1.00 283.57 ? 269 ASN B CB  1 
ATOM   5261  C CG  . ASN B 2 269 ? 96.925  84.819  59.480  1.00 379.59 ? 269 ASN B CG  1 
ATOM   5262  O OD1 . ASN B 2 269 ? 95.955  85.532  59.207  1.00 374.63 ? 269 ASN B OD1 1 
ATOM   5263  N ND2 . ASN B 2 269 ? 96.958  83.530  59.177  1.00 424.81 ? 269 ASN B ND2 1 
ATOM   5264  N N   . PRO B 2 270 ? 96.466  88.461  61.580  1.00 211.27 ? 270 PRO B N   1 
ATOM   5265  C CA  . PRO B 2 270 ? 95.655  88.903  62.711  1.00 216.25 ? 270 PRO B CA  1 
ATOM   5266  C C   . PRO B 2 270 ? 94.340  88.141  62.872  1.00 205.24 ? 270 PRO B C   1 
ATOM   5267  O O   . PRO B 2 270 ? 93.946  87.880  64.009  1.00 286.69 ? 270 PRO B O   1 
ATOM   5268  C CB  . PRO B 2 270 ? 95.412  90.406  62.463  1.00 249.96 ? 270 PRO B CB  1 
ATOM   5269  C CG  . PRO B 2 270 ? 95.676  90.610  60.999  1.00 263.80 ? 270 PRO B CG  1 
ATOM   5270  C CD  . PRO B 2 270 ? 96.674  89.543  60.603  1.00 248.80 ? 270 PRO B CD  1 
ATOM   5271  N N   . TYR B 2 271 ? 93.676  87.780  61.767  1.00 213.12 ? 271 TYR B N   1 
ATOM   5272  C CA  . TYR B 2 271 ? 92.332  87.225  61.858  1.00 247.36 ? 271 TYR B CA  1 
ATOM   5273  C C   . TYR B 2 271 ? 92.331  85.841  62.510  1.00 241.12 ? 271 TYR B C   1 
ATOM   5274  O O   . TYR B 2 271 ? 91.307  85.444  63.068  1.00 261.78 ? 271 TYR B O   1 
ATOM   5275  C CB  . TYR B 2 271 ? 91.726  87.213  60.455  1.00 321.11 ? 271 TYR B CB  1 
ATOM   5276  C CG  . TYR B 2 271 ? 91.518  88.621  59.924  1.00 383.42 ? 271 TYR B CG  1 
ATOM   5277  C CD1 . TYR B 2 271 ? 90.582  89.476  60.503  1.00 406.25 ? 271 TYR B CD1 1 
ATOM   5278  C CD2 . TYR B 2 271 ? 92.267  89.102  58.855  1.00 434.40 ? 271 TYR B CD2 1 
ATOM   5279  C CE1 . TYR B 2 271 ? 90.385  90.764  60.025  1.00 444.77 ? 271 TYR B CE1 1 
ATOM   5280  C CE2 . TYR B 2 271 ? 92.081  90.389  58.368  1.00 471.96 ? 271 TYR B CE2 1 
ATOM   5281  C CZ  . TYR B 2 271 ? 91.137  91.222  58.952  1.00 478.78 ? 271 TYR B CZ  1 
ATOM   5282  O OH  . TYR B 2 271 ? 90.952  92.491  58.477  1.00 512.18 ? 271 TYR B OH  1 
ATOM   5283  N N   . ARG B 2 272 ? 93.461  85.117  62.434  1.00 235.04 ? 272 ARG B N   1 
ATOM   5284  C CA  . ARG B 2 272 ? 93.668  83.888  63.189  1.00 269.57 ? 272 ARG B CA  1 
ATOM   5285  C C   . ARG B 2 272 ? 94.299  84.200  64.550  1.00 268.50 ? 272 ARG B C   1 
ATOM   5286  O O   . ARG B 2 272 ? 93.766  83.792  65.579  1.00 227.86 ? 272 ARG B O   1 
ATOM   5287  C CB  . ARG B 2 272 ? 94.531  82.927  62.363  1.00 290.99 ? 272 ARG B CB  1 
ATOM   5288  C CG  . ARG B 2 272 ? 94.867  81.612  63.047  1.00 292.76 ? 272 ARG B CG  1 
ATOM   5289  C CD  . ARG B 2 272 ? 95.798  80.740  62.225  1.00 289.74 ? 272 ARG B CD  1 
ATOM   5290  N NE  . ARG B 2 272 ? 96.368  79.629  62.997  1.00 348.98 ? 272 ARG B NE  1 
ATOM   5291  C CZ  . ARG B 2 272 ? 95.752  78.483  63.337  1.00 331.80 ? 272 ARG B CZ  1 
ATOM   5292  N NH1 . ARG B 2 272 ? 96.376  77.595  64.103  1.00 253.13 ? 272 ARG B NH1 1 
ATOM   5293  N NH2 . ARG B 2 272 ? 94.521  78.211  62.923  1.00 305.44 ? 272 ARG B NH2 1 
ATOM   5294  N N   . ASN B 2 273 ? 95.438  84.907  64.563  1.00 289.66 ? 273 ASN B N   1 
ATOM   5295  C CA  . ASN B 2 273 ? 96.331  84.888  65.718  1.00 262.55 ? 273 ASN B CA  1 
ATOM   5296  C C   . ASN B 2 273 ? 95.857  85.822  66.835  1.00 165.64 ? 273 ASN B C   1 
ATOM   5297  O O   . ASN B 2 273 ? 96.193  85.562  67.967  1.00 185.65 ? 273 ASN B O   1 
ATOM   5298  C CB  . ASN B 2 273 ? 97.789  85.188  65.333  1.00 295.85 ? 273 ASN B CB  1 
ATOM   5299  C CG  . ASN B 2 273 ? 98.427  84.171  64.401  1.00 302.42 ? 273 ASN B CG  1 
ATOM   5300  O OD1 . ASN B 2 273 ? 97.818  83.160  64.026  1.00 275.40 ? 273 ASN B OD1 1 
ATOM   5301  N ND2 . ASN B 2 273 ? 99.665  84.444  64.009  1.00 296.80 ? 273 ASN B ND2 1 
ATOM   5302  N N   . LEU B 2 274 ? 95.110  86.899  66.576  1.00 152.33 ? 274 LEU B N   1 
ATOM   5303  C CA  . LEU B 2 274 ? 94.591  87.738  67.662  1.00 172.29 ? 274 LEU B CA  1 
ATOM   5304  C C   . LEU B 2 274 ? 93.567  86.974  68.496  1.00 194.67 ? 274 LEU B C   1 
ATOM   5305  O O   . LEU B 2 274 ? 93.777  86.864  69.699  1.00 293.42 ? 274 LEU B O   1 
ATOM   5306  C CB  . LEU B 2 274 ? 93.977  89.051  67.149  1.00 197.08 ? 274 LEU B CB  1 
ATOM   5307  C CG  . LEU B 2 274 ? 93.162  89.886  68.143  1.00 183.28 ? 274 LEU B CG  1 
ATOM   5308  C CD1 . LEU B 2 274 ? 94.051  90.502  69.219  1.00 226.70 ? 274 LEU B CD1 1 
ATOM   5309  C CD2 . LEU B 2 274 ? 92.405  90.979  67.416  1.00 252.91 ? 274 LEU B CD2 1 
ATOM   5310  N N   . PRO B 2 275 ? 92.451  86.438  67.953  1.00 175.78 ? 275 PRO B N   1 
ATOM   5311  C CA  . PRO B 2 275 ? 91.487  85.732  68.786  1.00 192.46 ? 275 PRO B CA  1 
ATOM   5312  C C   . PRO B 2 275 ? 92.058  84.417  69.329  1.00 202.60 ? 275 PRO B C   1 
ATOM   5313  O O   . PRO B 2 275 ? 91.676  84.030  70.429  1.00 207.20 ? 275 PRO B O   1 
ATOM   5314  C CB  . PRO B 2 275 ? 90.293  85.536  67.848  1.00 231.14 ? 275 PRO B CB  1 
ATOM   5315  C CG  . PRO B 2 275 ? 90.936  85.420  66.497  1.00 290.04 ? 275 PRO B CG  1 
ATOM   5316  C CD  . PRO B 2 275 ? 92.039  86.450  66.545  1.00 251.04 ? 275 PRO B CD  1 
ATOM   5317  N N   . LEU B 2 276 ? 92.966  83.750  68.594  1.00 174.53 ? 276 LEU B N   1 
ATOM   5318  C CA  . LEU B 2 276 ? 93.620  82.551  69.106  1.00 219.21 ? 276 LEU B CA  1 
ATOM   5319  C C   . LEU B 2 276 ? 94.540  82.875  70.295  1.00 240.41 ? 276 LEU B C   1 
ATOM   5320  O O   . LEU B 2 276 ? 94.502  82.182  71.302  1.00 232.46 ? 276 LEU B O   1 
ATOM   5321  C CB  . LEU B 2 276 ? 94.375  81.843  67.974  1.00 213.15 ? 276 LEU B CB  1 
ATOM   5322  C CG  . LEU B 2 276 ? 95.018  80.493  68.309  1.00 301.71 ? 276 LEU B CG  1 
ATOM   5323  C CD1 . LEU B 2 276 ? 94.031  79.482  68.891  1.00 370.98 ? 276 LEU B CD1 1 
ATOM   5324  C CD2 . LEU B 2 276 ? 95.660  79.899  67.065  1.00 374.41 ? 276 LEU B CD2 1 
ATOM   5325  N N   . ALA B 2 277 ? 95.368  83.920  70.210  1.00 254.48 ? 277 ALA B N   1 
ATOM   5326  C CA  . ALA B 2 277 ? 96.292  84.254  71.291  1.00 232.78 ? 277 ALA B CA  1 
ATOM   5327  C C   . ALA B 2 277 ? 95.544  84.627  72.564  1.00 164.33 ? 277 ALA B C   1 
ATOM   5328  O O   . ALA B 2 277 ? 95.999  84.249  73.636  1.00 183.13 ? 277 ALA B O   1 
ATOM   5329  C CB  . ALA B 2 277 ? 97.224  85.366  70.877  1.00 262.08 ? 277 ALA B CB  1 
ATOM   5330  N N   . ILE B 2 278 ? 94.421  85.356  72.443  1.00 142.11 ? 278 ILE B N   1 
ATOM   5331  C CA  . ILE B 2 278 ? 93.550  85.662  73.576  1.00 176.53 ? 278 ILE B CA  1 
ATOM   5332  C C   . ILE B 2 278 ? 93.077  84.375  74.259  1.00 187.79 ? 278 ILE B C   1 
ATOM   5333  O O   . ILE B 2 278 ? 93.280  84.233  75.466  1.00 206.27 ? 278 ILE B O   1 
ATOM   5334  C CB  . ILE B 2 278 ? 92.324  86.535  73.192  1.00 183.57 ? 278 ILE B CB  1 
ATOM   5335  C CG1 . ILE B 2 278 ? 92.705  87.951  72.715  1.00 183.53 ? 278 ILE B CG1 1 
ATOM   5336  C CG2 . ILE B 2 278 ? 91.276  86.561  74.321  1.00 129.84 ? 278 ILE B CG2 1 
ATOM   5337  C CD1 . ILE B 2 278 ? 93.039  88.981  73.776  1.00 211.72 ? 278 ILE B CD1 1 
ATOM   5338  N N   . ILE B 2 279 ? 92.431  83.468  73.517  1.00 179.01 ? 279 ILE B N   1 
ATOM   5339  C CA  . ILE B 2 279 ? 91.736  82.357  74.154  1.00 211.18 ? 279 ILE B CA  1 
ATOM   5340  C C   . ILE B 2 279 ? 92.716  81.242  74.542  1.00 186.94 ? 279 ILE B C   1 
ATOM   5341  O O   . ILE B 2 279 ? 92.363  80.427  75.395  1.00 275.74 ? 279 ILE B O   1 
ATOM   5342  C CB  . ILE B 2 279 ? 90.551  81.864  73.287  1.00 275.48 ? 279 ILE B CB  1 
ATOM   5343  C CG1 . ILE B 2 279 ? 89.555  80.983  74.057  1.00 331.93 ? 279 ILE B CG1 1 
ATOM   5344  C CG2 . ILE B 2 279 ? 91.008  81.136  72.032  1.00 328.67 ? 279 ILE B CG2 1 
ATOM   5345  C CD1 . ILE B 2 279 ? 89.004  81.571  75.336  1.00 351.62 ? 279 ILE B CD1 1 
ATOM   5346  N N   . ILE B 2 280 ? 93.920  81.168  73.949  1.00 157.20 ? 280 ILE B N   1 
ATOM   5347  C CA  . ILE B 2 280 ? 94.975  80.308  74.481  1.00 231.57 ? 280 ILE B CA  1 
ATOM   5348  C C   . ILE B 2 280 ? 95.448  80.876  75.821  1.00 236.63 ? 280 ILE B C   1 
ATOM   5349  O O   . ILE B 2 280 ? 95.626  80.124  76.776  1.00 234.28 ? 280 ILE B O   1 
ATOM   5350  C CB  . ILE B 2 280 ? 96.137  80.114  73.475  1.00 255.78 ? 280 ILE B CB  1 
ATOM   5351  C CG1 . ILE B 2 280 ? 95.690  79.365  72.211  1.00 359.84 ? 280 ILE B CG1 1 
ATOM   5352  C CG2 . ILE B 2 280 ? 97.330  79.411  74.118  1.00 210.75 ? 280 ILE B CG2 1 
ATOM   5353  C CD1 . ILE B 2 280 ? 95.327  77.900  72.407  1.00 404.80 ? 280 ILE B CD1 1 
ATOM   5354  N N   . SER B 2 281 ? 95.647  82.196  75.874  1.00 231.10 ? 281 SER B N   1 
ATOM   5355  C CA  . SER B 2 281 ? 96.293  82.847  77.003  1.00 235.87 ? 281 SER B CA  1 
ATOM   5356  C C   . SER B 2 281 ? 95.432  82.885  78.269  1.00 162.64 ? 281 SER B C   1 
ATOM   5357  O O   . SER B 2 281 ? 95.898  82.425  79.299  1.00 225.46 ? 281 SER B O   1 
ATOM   5358  C CB  . SER B 2 281 ? 96.743  84.225  76.635  1.00 253.34 ? 281 SER B CB  1 
ATOM   5359  O OG  . SER B 2 281 ? 97.327  84.876  77.759  1.00 222.23 ? 281 SER B OG  1 
ATOM   5360  N N   . LEU B 2 282 ? 94.213  83.424  78.244  1.00 140.71 ? 282 LEU B N   1 
ATOM   5361  C CA  . LEU B 2 282 ? 93.549  83.750  79.514  1.00 198.95 ? 282 LEU B CA  1 
ATOM   5362  C C   . LEU B 2 282 ? 93.097  82.552  80.355  1.00 198.41 ? 282 LEU B C   1 
ATOM   5363  O O   . LEU B 2 282 ? 93.151  82.625  81.587  1.00 256.37 ? 282 LEU B O   1 
ATOM   5364  C CB  . LEU B 2 282 ? 92.387  84.715  79.286  1.00 201.28 ? 282 LEU B CB  1 
ATOM   5365  C CG  . LEU B 2 282 ? 92.802  86.148  79.603  1.00 202.32 ? 282 LEU B CG  1 
ATOM   5366  C CD1 . LEU B 2 282 ? 93.637  86.709  78.462  1.00 165.33 ? 282 LEU B CD1 1 
ATOM   5367  C CD2 . LEU B 2 282 ? 91.594  86.992  79.931  1.00 187.30 ? 282 LEU B CD2 1 
ATOM   5368  N N   . PRO B 2 283 ? 92.638  81.434  79.777  1.00 199.56 ? 283 PRO B N   1 
ATOM   5369  C CA  . PRO B 2 283 ? 92.535  80.183  80.533  1.00 238.53 ? 283 PRO B CA  1 
ATOM   5370  C C   . PRO B 2 283 ? 93.847  79.709  81.177  1.00 196.75 ? 283 PRO B C   1 
ATOM   5371  O O   . PRO B 2 283 ? 93.790  79.273  82.328  1.00 266.23 ? 283 PRO B O   1 
ATOM   5372  C CB  . PRO B 2 283 ? 92.017  79.202  79.472  1.00 324.18 ? 283 PRO B CB  1 
ATOM   5373  C CG  . PRO B 2 283 ? 91.265  80.102  78.531  1.00 338.07 ? 283 PRO B CG  1 
ATOM   5374  C CD  . PRO B 2 283 ? 92.173  81.305  78.397  1.00 266.37 ? 283 PRO B CD  1 
ATOM   5375  N N   . ILE B 2 284 ? 94.998  79.793  80.477  1.00 115.82 ? 284 ILE B N   1 
ATOM   5376  C CA  . ILE B 2 284 ? 96.285  79.497  81.110  1.00 179.06 ? 284 ILE B CA  1 
ATOM   5377  C C   . ILE B 2 284 ? 96.517  80.383  82.352  1.00 209.12 ? 284 ILE B C   1 
ATOM   5378  O O   . ILE B 2 284 ? 96.853  79.888  83.425  1.00 183.17 ? 284 ILE B O   1 
ATOM   5379  C CB  . ILE B 2 284 ? 97.448  79.586  80.094  1.00 208.02 ? 284 ILE B CB  1 
ATOM   5380  C CG1 . ILE B 2 284 ? 97.402  78.379  79.153  1.00 303.42 ? 284 ILE B CG1 1 
ATOM   5381  C CG2 . ILE B 2 284 ? 98.820  79.739  80.768  1.00 223.56 ? 284 ILE B CG2 1 
ATOM   5382  C CD1 . ILE B 2 284 ? 98.383  78.427  78.003  1.00 347.90 ? 284 ILE B CD1 1 
ATOM   5383  N N   . VAL B 2 285 ? 96.341  81.699  82.209  1.00 221.30 ? 285 VAL B N   1 
ATOM   5384  C CA  . VAL B 2 285 ? 96.542  82.635  83.302  1.00 186.05 ? 285 VAL B CA  1 
ATOM   5385  C C   . VAL B 2 285 ? 95.625  82.303  84.475  1.00 184.22 ? 285 VAL B C   1 
ATOM   5386  O O   . VAL B 2 285 ? 96.121  82.204  85.598  1.00 284.28 ? 285 VAL B O   1 
ATOM   5387  C CB  . VAL B 2 285 ? 96.349  84.082  82.832  1.00 197.37 ? 285 VAL B CB  1 
ATOM   5388  C CG1 . VAL B 2 285 ? 96.255  85.049  83.996  1.00 206.57 ? 285 VAL B CG1 1 
ATOM   5389  C CG2 . VAL B 2 285 ? 97.474  84.483  81.872  1.00 233.62 ? 285 VAL B CG2 1 
ATOM   5390  N N   . THR B 2 286 ? 94.325  82.122  84.223  1.00 194.30 ? 286 THR B N   1 
ATOM   5391  C CA  . THR B 2 286 ? 93.382  81.846  85.303  1.00 218.17 ? 286 THR B CA  1 
ATOM   5392  C C   . THR B 2 286 ? 93.757  80.566  86.058  1.00 216.53 ? 286 THR B C   1 
ATOM   5393  O O   . THR B 2 286 ? 93.719  80.563  87.292  1.00 236.13 ? 286 THR B O   1 
ATOM   5394  C CB  . THR B 2 286 ? 91.927  81.764  84.818  1.00 240.09 ? 286 THR B CB  1 
ATOM   5395  O OG1 . THR B 2 286 ? 91.612  82.964  84.114  1.00 269.64 ? 286 THR B OG1 1 
ATOM   5396  C CG2 . THR B 2 286 ? 90.940  81.585  85.955  1.00 205.27 ? 286 THR B CG2 1 
ATOM   5397  N N   . LEU B 2 287 ? 94.109  79.501  85.321  1.00 200.90 ? 287 LEU B N   1 
ATOM   5398  C CA  . LEU B 2 287 ? 94.548  78.245  85.916  1.00 226.75 ? 287 LEU B CA  1 
ATOM   5399  C C   . LEU B 2 287 ? 95.767  78.471  86.815  1.00 238.50 ? 287 LEU B C   1 
ATOM   5400  O O   . LEU B 2 287 ? 95.753  78.048  87.978  1.00 285.93 ? 287 LEU B O   1 
ATOM   5401  C CB  . LEU B 2 287 ? 94.861  77.242  84.797  1.00 274.42 ? 287 LEU B CB  1 
ATOM   5402  C CG  . LEU B 2 287 ? 95.440  75.896  85.230  1.00 399.05 ? 287 LEU B CG  1 
ATOM   5403  C CD1 . LEU B 2 287 ? 94.388  75.089  85.972  1.00 509.85 ? 287 LEU B CD1 1 
ATOM   5404  C CD2 . LEU B 2 287 ? 95.984  75.128  84.034  1.00 422.01 ? 287 LEU B CD2 1 
ATOM   5405  N N   . VAL B 2 288 ? 96.810  79.127  86.274  1.00 195.87 ? 288 VAL B N   1 
ATOM   5406  C CA  . VAL B 2 288 ? 98.053  79.353  87.007  1.00 213.97 ? 288 VAL B CA  1 
ATOM   5407  C C   . VAL B 2 288 ? 97.797  80.139  88.299  1.00 163.72 ? 288 VAL B C   1 
ATOM   5408  O O   . VAL B 2 288 ? 98.371  79.827  89.341  1.00 205.19 ? 288 VAL B O   1 
ATOM   5409  C CB  . VAL B 2 288 ? 99.105  80.012  86.104  1.00 238.11 ? 288 VAL B CB  1 
ATOM   5410  C CG1 . VAL B 2 288 ? 100.261 80.596  86.896  1.00 247.29 ? 288 VAL B CG1 1 
ATOM   5411  C CG2 . VAL B 2 288 ? 99.606  79.009  85.073  1.00 265.65 ? 288 VAL B CG2 1 
ATOM   5412  N N   . TYR B 2 289 ? 96.901  81.119  88.230  1.00 190.42 ? 289 TYR B N   1 
ATOM   5413  C CA  . TYR B 2 289 ? 96.586  81.965  89.373  1.00 216.17 ? 289 TYR B CA  1 
ATOM   5414  C C   . TYR B 2 289 ? 95.846  81.234  90.489  1.00 212.17 ? 289 TYR B C   1 
ATOM   5415  O O   . TYR B 2 289 ? 96.208  81.417  91.647  1.00 197.63 ? 289 TYR B O   1 
ATOM   5416  C CB  . TYR B 2 289 ? 95.808  83.180  88.866  1.00 210.38 ? 289 TYR B CB  1 
ATOM   5417  C CG  . TYR B 2 289 ? 96.700  84.305  88.365  1.00 208.68 ? 289 TYR B CG  1 
ATOM   5418  C CD1 . TYR B 2 289 ? 98.065  84.118  88.040  1.00 178.25 ? 289 TYR B CD1 1 
ATOM   5419  C CD2 . TYR B 2 289 ? 96.151  85.577  88.231  1.00 172.33 ? 289 TYR B CD2 1 
ATOM   5420  C CE1 . TYR B 2 289 ? 98.846  85.173  87.595  1.00 161.50 ? 289 TYR B CE1 1 
ATOM   5421  C CE2 . TYR B 2 289 ? 96.922  86.635  87.791  1.00 171.77 ? 289 TYR B CE2 1 
ATOM   5422  C CZ  . TYR B 2 289 ? 98.264  86.433  87.481  1.00 196.47 ? 289 TYR B CZ  1 
ATOM   5423  O OH  . TYR B 2 289 ? 99.002  87.494  87.057  1.00 137.21 ? 289 TYR B OH  1 
ATOM   5424  N N   . VAL B 2 290 ? 94.831  80.430  90.172  1.00 201.82 ? 290 VAL B N   1 
ATOM   5425  C CA  . VAL B 2 290 ? 94.115  79.753  91.241  1.00 205.81 ? 290 VAL B CA  1 
ATOM   5426  C C   . VAL B 2 290 ? 94.981  78.646  91.843  1.00 179.95 ? 290 VAL B C   1 
ATOM   5427  O O   . VAL B 2 290 ? 94.961  78.499  93.075  1.00 246.37 ? 290 VAL B O   1 
ATOM   5428  C CB  . VAL B 2 290 ? 92.737  79.242  90.804  1.00 264.84 ? 290 VAL B CB  1 
ATOM   5429  C CG1 . VAL B 2 290 ? 91.867  80.415  90.410  1.00 225.16 ? 290 VAL B CG1 1 
ATOM   5430  C CG2 . VAL B 2 290 ? 92.803  78.173  89.713  1.00 292.50 ? 290 VAL B CG2 1 
ATOM   5431  N N   . LEU B 2 291 ? 95.734  77.903  91.021  1.00 128.25 ? 291 LEU B N   1 
ATOM   5432  C CA  . LEU B 2 291 ? 96.685  76.937  91.580  1.00 200.53 ? 291 LEU B CA  1 
ATOM   5433  C C   . LEU B 2 291 ? 97.809  77.572  92.432  1.00 197.46 ? 291 LEU B C   1 
ATOM   5434  O O   . LEU B 2 291 ? 98.225  76.987  93.443  1.00 200.01 ? 291 LEU B O   1 
ATOM   5435  C CB  . LEU B 2 291 ? 97.274  76.111  90.435  1.00 263.91 ? 291 LEU B CB  1 
ATOM   5436  C CG  . LEU B 2 291 ? 96.298  75.217  89.664  1.00 345.03 ? 291 LEU B CG  1 
ATOM   5437  C CD1 . LEU B 2 291 ? 97.026  74.517  88.525  1.00 365.76 ? 291 LEU B CD1 1 
ATOM   5438  C CD2 . LEU B 2 291 ? 95.620  74.187  90.563  1.00 403.87 ? 291 LEU B CD2 1 
ATOM   5439  N N   . THR B 2 292 ? 98.304  78.761  92.052  1.00 202.65 ? 292 THR B N   1 
ATOM   5440  C CA  . THR B 2 292 ? 99.328  79.444  92.840  1.00 195.33 ? 292 THR B CA  1 
ATOM   5441  C C   . THR B 2 292 ? 98.766  79.899  94.187  1.00 181.17 ? 292 THR B C   1 
ATOM   5442  O O   . THR B 2 292 ? 99.422  79.718  95.211  1.00 232.85 ? 292 THR B O   1 
ATOM   5443  C CB  . THR B 2 292 ? 99.922  80.636  92.082  1.00 226.36 ? 292 THR B CB  1 
ATOM   5444  O OG1 . THR B 2 292 ? 100.510 80.145  90.882  1.00 256.76 ? 292 THR B OG1 1 
ATOM   5445  C CG2 . THR B 2 292 ? 100.981 81.398  92.853  1.00 189.80 ? 292 THR B CG2 1 
ATOM   5446  N N   . ASN B 2 293 ? 97.567  80.488  94.199  1.00 154.01 ? 293 ASN B N   1 
ATOM   5447  C CA  . ASN B 2 293 ? 96.915  80.810  95.464  1.00 197.67 ? 293 ASN B CA  1 
ATOM   5448  C C   . ASN B 2 293 ? 96.671  79.568  96.330  1.00 205.05 ? 293 ASN B C   1 
ATOM   5449  O O   . ASN B 2 293 ? 96.922  79.622  97.538  1.00 191.85 ? 293 ASN B O   1 
ATOM   5450  C CB  . ASN B 2 293 ? 95.629  81.598  95.239  1.00 214.14 ? 293 ASN B CB  1 
ATOM   5451  C CG  . ASN B 2 293 ? 95.968  83.039  94.950  1.00 198.04 ? 293 ASN B CG  1 
ATOM   5452  O OD1 . ASN B 2 293 ? 96.157  83.825  95.870  1.00 175.07 ? 293 ASN B OD1 1 
ATOM   5453  N ND2 . ASN B 2 293 ? 96.056  83.395  93.683  1.00 206.25 ? 293 ASN B ND2 1 
ATOM   5454  N N   . LEU B 2 294 ? 96.205  78.466  95.725  1.00 217.72 ? 294 LEU B N   1 
ATOM   5455  C CA  . LEU B 2 294 ? 96.086  77.202  96.442  1.00 263.31 ? 294 LEU B CA  1 
ATOM   5456  C C   . LEU B 2 294 ? 97.413  76.863  97.139  1.00 295.45 ? 294 LEU B C   1 
ATOM   5457  O O   . LEU B 2 294 ? 97.399  76.529  98.329  1.00 381.12 ? 294 LEU B O   1 
ATOM   5458  C CB  . LEU B 2 294 ? 95.627  76.103  95.473  1.00 326.10 ? 294 LEU B CB  1 
ATOM   5459  C CG  . LEU B 2 294 ? 95.613  74.679  96.038  1.00 380.23 ? 294 LEU B CG  1 
ATOM   5460  C CD1 . LEU B 2 294 ? 94.518  74.528  97.083  1.00 404.12 ? 294 LEU B CD1 1 
ATOM   5461  C CD2 . LEU B 2 294 ? 95.441  73.647  94.934  1.00 402.96 ? 294 LEU B CD2 1 
ATOM   5462  N N   . ALA B 2 295 ? 98.546  76.965  96.420  1.00 232.29 ? 295 ALA B N   1 
ATOM   5463  C CA  . ALA B 2 295 ? 99.853  76.708  97.011  1.00 180.19 ? 295 ALA B CA  1 
ATOM   5464  C C   . ALA B 2 295 ? 100.100 77.607  98.235  1.00 231.08 ? 295 ALA B C   1 
ATOM   5465  O O   . ALA B 2 295 ? 100.396 77.073  99.304  1.00 292.57 ? 295 ALA B O   1 
ATOM   5466  C CB  . ALA B 2 295 ? 100.923 76.842  95.955  1.00 188.43 ? 295 ALA B CB  1 
ATOM   5467  N N   . TYR B 2 296 ? 99.958  78.945  98.118  1.00 265.32 ? 296 TYR B N   1 
ATOM   5468  C CA  . TYR B 2 296 ? 100.164 79.862  99.243  1.00 267.09 ? 296 TYR B CA  1 
ATOM   5469  C C   . TYR B 2 296 ? 99.313  79.480  100.462 1.00 267.17 ? 296 TYR B C   1 
ATOM   5470  O O   . TYR B 2 296 ? 99.838  79.413  101.576 1.00 298.76 ? 296 TYR B O   1 
ATOM   5471  C CB  . TYR B 2 296 ? 99.860  81.331  98.927  1.00 268.70 ? 296 TYR B CB  1 
ATOM   5472  C CG  . TYR B 2 296 ? 100.685 81.987  97.829  1.00 261.64 ? 296 TYR B CG  1 
ATOM   5473  C CD1 . TYR B 2 296 ? 102.049 81.707  97.668  1.00 217.21 ? 296 TYR B CD1 1 
ATOM   5474  C CD2 . TYR B 2 296 ? 100.088 82.901  96.955  1.00 176.62 ? 296 TYR B CD2 1 
ATOM   5475  C CE1 . TYR B 2 296 ? 102.803 82.301  96.661  1.00 210.52 ? 296 TYR B CE1 1 
ATOM   5476  C CE2 . TYR B 2 296 ? 100.836 83.499  95.950  1.00 234.15 ? 296 TYR B CE2 1 
ATOM   5477  C CZ  . TYR B 2 296 ? 102.189 83.203  95.798  1.00 246.77 ? 296 TYR B CZ  1 
ATOM   5478  O OH  . TYR B 2 296 ? 102.871 83.826  94.786  1.00 213.11 ? 296 TYR B OH  1 
ATOM   5479  N N   . PHE B 2 297 ? 98.017  79.220  100.257 1.00 207.52 ? 297 PHE B N   1 
ATOM   5480  C CA  . PHE B 2 297 ? 97.146  78.817  101.354 1.00 223.65 ? 297 PHE B CA  1 
ATOM   5481  C C   . PHE B 2 297 ? 97.433  77.414  101.931 1.00 260.51 ? 297 PHE B C   1 
ATOM   5482  O O   . PHE B 2 297 ? 96.990  77.152  103.051 1.00 262.17 ? 297 PHE B O   1 
ATOM   5483  C CB  . PHE B 2 297 ? 95.694  78.907  100.894 1.00 227.44 ? 297 PHE B CB  1 
ATOM   5484  C CG  . PHE B 2 297 ? 95.177  80.306  100.726 1.00 247.25 ? 297 PHE B CG  1 
ATOM   5485  C CD1 . PHE B 2 297 ? 95.127  81.159  101.817 1.00 223.05 ? 297 PHE B CD1 1 
ATOM   5486  C CD2 . PHE B 2 297 ? 94.731  80.766  99.488  1.00 300.35 ? 297 PHE B CD2 1 
ATOM   5487  C CE1 . PHE B 2 297 ? 94.643  82.448  101.665 1.00 208.28 ? 297 PHE B CE1 1 
ATOM   5488  C CE2 . PHE B 2 297 ? 94.246  82.057  99.337  1.00 302.89 ? 297 PHE B CE2 1 
ATOM   5489  C CZ  . PHE B 2 297 ? 94.202  82.893  100.426 1.00 256.48 ? 297 PHE B CZ  1 
ATOM   5490  N N   . THR B 2 298 ? 98.141  76.505  101.229 1.00 251.22 ? 298 THR B N   1 
ATOM   5491  C CA  . THR B 2 298 ? 98.609  75.276  101.874 1.00 209.98 ? 298 THR B CA  1 
ATOM   5492  C C   . THR B 2 298 ? 99.767  75.564  102.836 1.00 246.25 ? 298 THR B C   1 
ATOM   5493  O O   . THR B 2 298 ? 99.873  74.874  103.848 1.00 323.13 ? 298 THR B O   1 
ATOM   5494  C CB  . THR B 2 298 ? 99.033  74.163  100.900 1.00 268.57 ? 298 THR B CB  1 
ATOM   5495  O OG1 . THR B 2 298 ? 100.078 74.588  100.022 1.00 268.29 ? 298 THR B OG1 1 
ATOM   5496  C CG2 . THR B 2 298 ? 97.883  73.655  100.060 1.00 333.26 ? 298 THR B CG2 1 
ATOM   5497  N N   . THR B 2 299 ? 100.628 76.559  102.539 1.00 237.11 ? 299 THR B N   1 
ATOM   5498  C CA  . THR B 2 299 ? 101.844 76.805  103.313 1.00 223.00 ? 299 THR B CA  1 
ATOM   5499  C C   . THR B 2 299 ? 101.630 77.758  104.491 1.00 240.62 ? 299 THR B C   1 
ATOM   5500  O O   . THR B 2 299 ? 102.237 77.548  105.545 1.00 263.80 ? 299 THR B O   1 
ATOM   5501  C CB  . THR B 2 299 ? 102.963 77.382  102.446 1.00 239.15 ? 299 THR B CB  1 
ATOM   5502  O OG1 . THR B 2 299 ? 103.130 76.542  101.306 1.00 215.04 ? 299 THR B OG1 1 
ATOM   5503  C CG2 . THR B 2 299 ? 104.289 77.451  103.165 1.00 236.48 ? 299 THR B CG2 1 
ATOM   5504  N N   . LEU B 2 300 ? 100.787 78.794  104.319 1.00 190.63 ? 300 LEU B N   1 
ATOM   5505  C CA  . LEU B 2 300 ? 100.715 79.890  105.282 1.00 253.16 ? 300 LEU B CA  1 
ATOM   5506  C C   . LEU B 2 300 ? 99.326  79.967  105.937 1.00 264.47 ? 300 LEU B C   1 
ATOM   5507  O O   . LEU B 2 300 ? 98.306  79.648  105.333 1.00 243.02 ? 300 LEU B O   1 
ATOM   5508  C CB  . LEU B 2 300 ? 101.080 81.202  104.572 1.00 239.97 ? 300 LEU B CB  1 
ATOM   5509  C CG  . LEU B 2 300 ? 102.448 81.266  103.877 1.00 278.95 ? 300 LEU B CG  1 
ATOM   5510  C CD1 . LEU B 2 300 ? 102.633 82.604  103.161 1.00 255.04 ? 300 LEU B CD1 1 
ATOM   5511  C CD2 . LEU B 2 300 ? 103.609 81.044  104.842 1.00 293.23 ? 300 LEU B CD2 1 
ATOM   5512  N N   . SER B 2 301 ? 99.304  80.405  107.203 1.00 261.95 ? 301 SER B N   1 
ATOM   5513  C CA  . SER B 2 301 ? 98.088  80.823  107.887 1.00 247.58 ? 301 SER B CA  1 
ATOM   5514  C C   . SER B 2 301 ? 97.585  82.159  107.343 1.00 196.26 ? 301 SER B C   1 
ATOM   5515  O O   . SER B 2 301 ? 98.351  82.911  106.739 1.00 223.50 ? 301 SER B O   1 
ATOM   5516  C CB  . SER B 2 301 ? 98.347  80.957  109.361 1.00 308.97 ? 301 SER B CB  1 
ATOM   5517  O OG  . SER B 2 301 ? 99.292  81.993  109.619 1.00 294.29 ? 301 SER B OG  1 
ATOM   5518  N N   . THR B 2 302 ? 96.299  82.464  107.579 1.00 215.71 ? 302 THR B N   1 
ATOM   5519  C CA  . THR B 2 302 ? 95.715  83.743  107.179 1.00 264.79 ? 302 THR B CA  1 
ATOM   5520  C C   . THR B 2 302 ? 96.461  84.906  107.845 1.00 248.06 ? 302 THR B C   1 
ATOM   5521  O O   . THR B 2 302 ? 96.737  85.890  107.166 1.00 228.66 ? 302 THR B O   1 
ATOM   5522  C CB  . THR B 2 302 ? 94.199  83.814  107.445 1.00 339.61 ? 302 THR B CB  1 
ATOM   5523  O OG1 . THR B 2 302 ? 93.962  83.512  108.821 1.00 419.95 ? 302 THR B OG1 1 
ATOM   5524  C CG2 . THR B 2 302 ? 93.381  82.882  106.569 1.00 363.33 ? 302 THR B CG2 1 
ATOM   5525  N N   . GLU B 2 303 ? 96.791  84.796  109.145 1.00 282.77 ? 303 GLU B N   1 
ATOM   5526  C CA  . GLU B 2 303 ? 97.450  85.877  109.880 1.00 330.50 ? 303 GLU B CA  1 
ATOM   5527  C C   . GLU B 2 303 ? 98.866  86.153  109.341 1.00 297.44 ? 303 GLU B C   1 
ATOM   5528  O O   . GLU B 2 303 ? 99.277  87.315  109.318 1.00 249.54 ? 303 GLU B O   1 
ATOM   5529  C CB  . GLU B 2 303 ? 97.443  85.624  111.402 1.00 438.45 ? 303 GLU B CB  1 
ATOM   5530  C CG  . GLU B 2 303 ? 98.187  84.373  111.886 1.00 523.21 ? 303 GLU B CG  1 
ATOM   5531  C CD  . GLU B 2 303 ? 98.533  84.314  113.370 1.00 570.78 ? 303 GLU B CD  1 
ATOM   5532  O OE1 . GLU B 2 303 ? 98.224  85.272  114.111 1.00 586.21 ? 303 GLU B OE1 1 
ATOM   5533  O OE2 . GLU B 2 303 ? 99.121  83.298  113.785 1.00 580.14 ? 303 GLU B OE2 1 
ATOM   5534  N N   . GLN B 2 304 ? 99.612  85.124  108.896 1.00 274.27 ? 304 GLN B N   1 
ATOM   5535  C CA  . GLN B 2 304 ? 100.884 85.332  108.214 1.00 232.13 ? 304 GLN B CA  1 
ATOM   5536  C C   . GLN B 2 304 ? 100.687 86.102  106.912 1.00 228.91 ? 304 GLN B C   1 
ATOM   5537  O O   . GLN B 2 304 ? 101.357 87.110  106.697 1.00 229.65 ? 304 GLN B O   1 
ATOM   5538  C CB  . GLN B 2 304 ? 101.564 84.004  107.880 1.00 243.40 ? 304 GLN B CB  1 
ATOM   5539  C CG  . GLN B 2 304 ? 102.283 83.381  109.062 1.00 256.07 ? 304 GLN B CG  1 
ATOM   5540  C CD  . GLN B 2 304 ? 102.611 81.927  108.819 1.00 284.97 ? 304 GLN B CD  1 
ATOM   5541  O OE1 . GLN B 2 304 ? 101.715 81.095  108.684 1.00 269.44 ? 304 GLN B OE1 1 
ATOM   5542  N NE2 . GLN B 2 304 ? 103.896 81.603  108.767 1.00 308.42 ? 304 GLN B NE2 1 
ATOM   5543  N N   . MET B 2 305 ? 99.786  85.622  106.042 1.00 229.70 ? 305 MET B N   1 
ATOM   5544  C CA  . MET B 2 305 ? 99.585  86.248  104.740 1.00 237.06 ? 305 MET B CA  1 
ATOM   5545  C C   . MET B 2 305 ? 99.042  87.681  104.873 1.00 253.71 ? 305 MET B C   1 
ATOM   5546  O O   . MET B 2 305 ? 99.336  88.511  104.012 1.00 380.73 ? 305 MET B O   1 
ATOM   5547  C CB  . MET B 2 305 ? 98.648  85.414  103.861 1.00 232.29 ? 305 MET B CB  1 
ATOM   5548  C CG  . MET B 2 305 ? 99.358  84.201  103.303 1.00 196.47 ? 305 MET B CG  1 
ATOM   5549  S SD  . MET B 2 305 ? 98.259  83.169  102.249 1.00 298.57 ? 305 MET B SD  1 
ATOM   5550  C CE  . MET B 2 305 ? 97.981  84.252  100.849 1.00 304.82 ? 305 MET B CE  1 
ATOM   5551  N N   . LEU B 2 306 ? 98.272  87.978  105.934 1.00 144.51 ? 306 LEU B N   1 
ATOM   5552  C CA  . LEU B 2 306 ? 97.713  89.308  106.153 1.00 228.98 ? 306 LEU B CA  1 
ATOM   5553  C C   . LEU B 2 306 ? 98.769  90.303  106.652 1.00 254.40 ? 306 LEU B C   1 
ATOM   5554  O O   . LEU B 2 306 ? 98.572  91.511  106.481 1.00 207.07 ? 306 LEU B O   1 
ATOM   5555  C CB  . LEU B 2 306 ? 96.545  89.184  107.147 1.00 278.65 ? 306 LEU B CB  1 
ATOM   5556  C CG  . LEU B 2 306 ? 95.261  88.580  106.566 1.00 249.38 ? 306 LEU B CG  1 
ATOM   5557  C CD1 . LEU B 2 306 ? 94.305  88.041  107.635 1.00 208.44 ? 306 LEU B CD1 1 
ATOM   5558  C CD2 . LEU B 2 306 ? 94.551  89.610  105.714 1.00 221.49 ? 306 LEU B CD2 1 
ATOM   5559  N N   . SER B 2 307 ? 99.862  89.804  107.267 1.00 269.63 ? 307 SER B N   1 
ATOM   5560  C CA  . SER B 2 307 ? 100.838 90.637  107.962 1.00 281.73 ? 307 SER B CA  1 
ATOM   5561  C C   . SER B 2 307 ? 102.223 90.646  107.308 1.00 275.10 ? 307 SER B C   1 
ATOM   5562  O O   . SER B 2 307 ? 103.014 91.526  107.645 1.00 392.76 ? 307 SER B O   1 
ATOM   5563  C CB  . SER B 2 307 ? 100.941 90.208  109.409 1.00 362.95 ? 307 SER B CB  1 
ATOM   5564  O OG  . SER B 2 307 ? 101.406 88.867  109.535 1.00 336.68 ? 307 SER B OG  1 
ATOM   5565  N N   . SER B 2 308 ? 102.518 89.694  106.406 1.00 291.37 ? 308 SER B N   1 
ATOM   5566  C CA  . SER B 2 308 ? 103.792 89.624  105.697 1.00 357.77 ? 308 SER B CA  1 
ATOM   5567  C C   . SER B 2 308 ? 103.838 90.597  104.511 1.00 377.00 ? 308 SER B C   1 
ATOM   5568  O O   . SER B 2 308 ? 102.815 90.890  103.886 1.00 290.48 ? 308 SER B O   1 
ATOM   5569  C CB  . SER B 2 308 ? 104.077 88.208  105.260 1.00 286.34 ? 308 SER B CB  1 
ATOM   5570  O OG  . SER B 2 308 ? 102.977 87.659  104.551 1.00 336.45 ? 308 SER B OG  1 
ATOM   5571  N N   . GLU B 2 309 ? 105.057 91.085  104.213 1.00 395.58 ? 309 GLU B N   1 
ATOM   5572  C CA  . GLU B 2 309 ? 105.284 92.119  103.213 1.00 372.17 ? 309 GLU B CA  1 
ATOM   5573  C C   . GLU B 2 309 ? 105.381 91.517  101.809 1.00 327.61 ? 309 GLU B C   1 
ATOM   5574  O O   . GLU B 2 309 ? 105.178 92.242  100.834 1.00 377.56 ? 309 GLU B O   1 
ATOM   5575  C CB  . GLU B 2 309 ? 106.574 92.901  103.492 1.00 461.83 ? 309 GLU B CB  1 
ATOM   5576  C CG  . GLU B 2 309 ? 106.668 93.527  104.881 1.00 531.57 ? 309 GLU B CG  1 
ATOM   5577  C CD  . GLU B 2 309 ? 107.294 92.679  105.979 1.00 586.66 ? 309 GLU B CD  1 
ATOM   5578  O OE1 . GLU B 2 309 ? 107.428 91.451  105.784 1.00 620.51 ? 309 GLU B OE1 1 
ATOM   5579  O OE2 . GLU B 2 309 ? 107.648 93.251  107.027 1.00 591.60 ? 309 GLU B OE2 1 
ATOM   5580  N N   . ALA B 2 310 ? 105.696 90.214  101.698 1.00 287.63 ? 310 ALA B N   1 
ATOM   5581  C CA  . ALA B 2 310 ? 106.103 89.634  100.423 1.00 299.55 ? 310 ALA B CA  1 
ATOM   5582  C C   . ALA B 2 310 ? 105.853 88.123  100.389 1.00 211.89 ? 310 ALA B C   1 
ATOM   5583  O O   . ALA B 2 310 ? 106.720 87.326  100.729 1.00 146.69 ? 310 ALA B O   1 
ATOM   5584  C CB  . ALA B 2 310 ? 107.556 89.972  100.176 1.00 379.33 ? 310 ALA B CB  1 
ATOM   5585  N N   . VAL B 2 311 ? 104.655 87.738  99.935  1.00 179.41 ? 311 VAL B N   1 
ATOM   5586  C CA  . VAL B 2 311 ? 104.096 86.415  100.196 1.00 170.41 ? 311 VAL B CA  1 
ATOM   5587  C C   . VAL B 2 311 ? 105.001 85.309  99.653  1.00 143.21 ? 311 VAL B C   1 
ATOM   5588  O O   . VAL B 2 311 ? 105.226 84.289  100.314 1.00 189.56 ? 311 VAL B O   1 
ATOM   5589  C CB  . VAL B 2 311 ? 102.682 86.283  99.599  1.00 196.07 ? 311 VAL B CB  1 
ATOM   5590  C CG1 . VAL B 2 311 ? 102.107 84.885  99.887  1.00 230.63 ? 311 VAL B CG1 1 
ATOM   5591  C CG2 . VAL B 2 311 ? 101.765 87.432  100.050 1.00 163.79 ? 311 VAL B CG2 1 
ATOM   5592  N N   . ALA B 2 312 ? 105.510 85.522  98.439  1.00 148.15 ? 312 ALA B N   1 
ATOM   5593  C CA  . ALA B 2 312 ? 106.336 84.535  97.768  1.00 172.94 ? 312 ALA B CA  1 
ATOM   5594  C C   . ALA B 2 312 ? 107.667 84.325  98.489  1.00 208.29 ? 312 ALA B C   1 
ATOM   5595  O O   . ALA B 2 312 ? 108.225 83.234  98.404  1.00 249.30 ? 312 ALA B O   1 
ATOM   5596  C CB  . ALA B 2 312 ? 106.557 84.957  96.348  1.00 252.50 ? 312 ALA B CB  1 
ATOM   5597  N N   . VAL B 2 313 ? 108.162 85.344  99.205  1.00 185.90 ? 313 VAL B N   1 
ATOM   5598  C CA  . VAL B 2 313 ? 109.397 85.231  99.970  1.00 186.79 ? 313 VAL B CA  1 
ATOM   5599  C C   . VAL B 2 313 ? 109.192 84.302  101.173 1.00 221.66 ? 313 VAL B C   1 
ATOM   5600  O O   . VAL B 2 313 ? 110.057 83.463  101.437 1.00 185.88 ? 313 VAL B O   1 
ATOM   5601  C CB  . VAL B 2 313 ? 109.883 86.625  100.393 1.00 197.79 ? 313 VAL B CB  1 
ATOM   5602  C CG1 . VAL B 2 313 ? 111.173 86.566  101.205 1.00 305.84 ? 313 VAL B CG1 1 
ATOM   5603  C CG2 . VAL B 2 313 ? 110.056 87.518  99.175  1.00 197.89 ? 313 VAL B CG2 1 
ATOM   5604  N N   . ASP B 2 314 ? 108.059 84.456  101.888 1.00 238.18 ? 314 ASP B N   1 
ATOM   5605  C CA  . ASP B 2 314 ? 107.700 83.607  103.021 1.00 247.16 ? 314 ASP B CA  1 
ATOM   5606  C C   . ASP B 2 314 ? 107.505 82.156  102.586 1.00 190.94 ? 314 ASP B C   1 
ATOM   5607  O O   . ASP B 2 314 ? 107.990 81.242  103.259 1.00 188.95 ? 314 ASP B O   1 
ATOM   5608  C CB  . ASP B 2 314 ? 106.457 84.138  103.748 1.00 297.27 ? 314 ASP B CB  1 
ATOM   5609  C CG  . ASP B 2 314 ? 106.705 85.329  104.667 1.00 388.20 ? 314 ASP B CG  1 
ATOM   5610  O OD1 . ASP B 2 314 ? 107.755 85.998  104.539 1.00 412.09 ? 314 ASP B OD1 1 
ATOM   5611  O OD2 . ASP B 2 314 ? 105.842 85.575  105.528 1.00 427.68 ? 314 ASP B OD2 1 
ATOM   5612  N N   . PHE B 2 315 ? 106.803 81.974  101.461 1.00 181.27 ? 315 PHE B N   1 
ATOM   5613  C CA  . PHE B 2 315 ? 106.669 80.678  100.811 1.00 184.68 ? 315 PHE B CA  1 
ATOM   5614  C C   . PHE B 2 315 ? 108.045 80.055  100.473 1.00 198.82 ? 315 PHE B C   1 
ATOM   5615  O O   . PHE B 2 315 ? 108.297 78.887  100.783 1.00 247.94 ? 315 PHE B O   1 
ATOM   5616  C CB  . PHE B 2 315 ? 105.731 80.839  99.610  1.00 195.02 ? 315 PHE B CB  1 
ATOM   5617  C CG  . PHE B 2 315 ? 105.386 79.544  98.922  1.00 232.18 ? 315 PHE B CG  1 
ATOM   5618  C CD1 . PHE B 2 315 ? 106.289 78.943  98.037  1.00 268.37 ? 315 PHE B CD1 1 
ATOM   5619  C CD2 . PHE B 2 315 ? 104.157 78.924  99.154  1.00 161.54 ? 315 PHE B CD2 1 
ATOM   5620  C CE1 . PHE B 2 315 ? 105.977 77.751  97.396  1.00 281.96 ? 315 PHE B CE1 1 
ATOM   5621  C CE2 . PHE B 2 315 ? 103.860 77.721  98.520  1.00 195.08 ? 315 PHE B CE2 1 
ATOM   5622  C CZ  . PHE B 2 315 ? 104.760 77.142  97.638  1.00 257.88 ? 315 PHE B CZ  1 
ATOM   5623  N N   . GLY B 2 316 ? 108.945 80.824  99.851  1.00 231.21 ? 316 GLY B N   1 
ATOM   5624  C CA  . GLY B 2 316 ? 110.306 80.382  99.566  1.00 265.55 ? 316 GLY B CA  1 
ATOM   5625  C C   . GLY B 2 316 ? 111.078 79.956  100.815 1.00 265.03 ? 316 GLY B C   1 
ATOM   5626  O O   . GLY B 2 316 ? 111.642 78.858  100.845 1.00 283.76 ? 316 GLY B O   1 
ATOM   5627  N N   . ASN B 2 317 ? 111.084 80.835  101.829 1.00 237.94 ? 317 ASN B N   1 
ATOM   5628  C CA  . ASN B 2 317 ? 111.760 80.595  103.098 1.00 258.18 ? 317 ASN B CA  1 
ATOM   5629  C C   . ASN B 2 317 ? 111.332 79.268  103.726 1.00 285.42 ? 317 ASN B C   1 
ATOM   5630  O O   . ASN B 2 317 ? 112.191 78.522  104.201 1.00 280.65 ? 317 ASN B O   1 
ATOM   5631  C CB  . ASN B 2 317 ? 111.538 81.757  104.074 1.00 254.09 ? 317 ASN B CB  1 
ATOM   5632  C CG  . ASN B 2 317 ? 112.518 82.908  103.909 1.00 334.01 ? 317 ASN B CG  1 
ATOM   5633  O OD1 . ASN B 2 317 ? 113.647 82.745  103.446 1.00 335.86 ? 317 ASN B OD1 1 
ATOM   5634  N ND2 . ASN B 2 317 ? 112.100 84.096  104.312 1.00 399.49 ? 317 ASN B ND2 1 
ATOM   5635  N N   . TYR B 2 318 ? 110.020 78.986  103.713 1.00 294.40 ? 318 TYR B N   1 
ATOM   5636  C CA  . TYR B 2 318 ? 109.467 77.786  104.331 1.00 294.31 ? 318 TYR B CA  1 
ATOM   5637  C C   . TYR B 2 318 ? 109.898 76.515  103.591 1.00 253.41 ? 318 TYR B C   1 
ATOM   5638  O O   . TYR B 2 318 ? 110.251 75.541  104.255 1.00 266.76 ? 318 TYR B O   1 
ATOM   5639  C CB  . TYR B 2 318 ? 107.943 77.912  104.398 1.00 309.48 ? 318 TYR B CB  1 
ATOM   5640  C CG  . TYR B 2 318 ? 107.247 76.798  105.163 1.00 331.01 ? 318 TYR B CG  1 
ATOM   5641  C CD1 . TYR B 2 318 ? 106.963 75.563  104.580 1.00 292.81 ? 318 TYR B CD1 1 
ATOM   5642  C CD2 . TYR B 2 318 ? 106.855 76.995  106.482 1.00 405.64 ? 318 TYR B CD2 1 
ATOM   5643  C CE1 . TYR B 2 318 ? 106.328 74.553  105.290 1.00 374.14 ? 318 TYR B CE1 1 
ATOM   5644  C CE2 . TYR B 2 318 ? 106.212 75.997  107.202 1.00 443.60 ? 318 TYR B CE2 1 
ATOM   5645  C CZ  . TYR B 2 318 ? 105.946 74.773  106.605 1.00 448.64 ? 318 TYR B CZ  1 
ATOM   5646  O OH  . TYR B 2 318 ? 105.316 73.786  107.309 1.00 518.92 ? 318 TYR B OH  1 
ATOM   5647  N N   . HIS B 2 319 ? 109.862 76.516  102.246 1.00 257.68 ? 319 HIS B N   1 
ATOM   5648  C CA  . HIS B 2 319 ? 110.068 75.298  101.469 1.00 270.72 ? 319 HIS B CA  1 
ATOM   5649  C C   . HIS B 2 319 ? 111.540 75.007  101.143 1.00 258.65 ? 319 HIS B C   1 
ATOM   5650  O O   . HIS B 2 319 ? 111.883 73.837  100.992 1.00 259.72 ? 319 HIS B O   1 
ATOM   5651  C CB  . HIS B 2 319 ? 109.194 75.312  100.208 1.00 250.05 ? 319 HIS B CB  1 
ATOM   5652  C CG  . HIS B 2 319 ? 107.754 75.110  100.550 1.00 249.01 ? 319 HIS B CG  1 
ATOM   5653  N ND1 . HIS B 2 319 ? 107.235 73.886  100.912 1.00 229.47 ? 319 HIS B ND1 1 
ATOM   5654  C CD2 . HIS B 2 319 ? 106.723 75.970  100.594 1.00 303.25 ? 319 HIS B CD2 1 
ATOM   5655  C CE1 . HIS B 2 319 ? 105.935 74.013  101.166 1.00 263.13 ? 319 HIS B CE1 1 
ATOM   5656  N NE2 . HIS B 2 319 ? 105.603 75.268  100.979 1.00 263.59 ? 319 HIS B NE2 1 
ATOM   5657  N N   . LEU B 2 320 ? 112.406 76.024  101.028 1.00 259.99 ? 320 LEU B N   1 
ATOM   5658  C CA  . LEU B 2 320 ? 113.696 75.841  100.360 1.00 297.15 ? 320 LEU B CA  1 
ATOM   5659  C C   . LEU B 2 320 ? 114.916 76.142  101.236 1.00 294.89 ? 320 LEU B C   1 
ATOM   5660  O O   . LEU B 2 320 ? 116.021 75.751  100.833 1.00 228.41 ? 320 LEU B O   1 
ATOM   5661  C CB  . LEU B 2 320 ? 113.706 76.733  99.115  1.00 339.68 ? 320 LEU B CB  1 
ATOM   5662  C CG  . LEU B 2 320 ? 112.628 76.425  98.076  1.00 367.50 ? 320 LEU B CG  1 
ATOM   5663  C CD1 . LEU B 2 320 ? 112.631 77.483  96.979  1.00 424.18 ? 320 LEU B CD1 1 
ATOM   5664  C CD2 . LEU B 2 320 ? 112.819 75.040  97.473  1.00 363.22 ? 320 LEU B CD2 1 
ATOM   5665  N N   . GLY B 2 321 ? 114.732 76.827  102.385 1.00 307.19 ? 321 GLY B N   1 
ATOM   5666  C CA  . GLY B 2 321 ? 115.802 77.050  103.352 1.00 349.49 ? 321 GLY B CA  1 
ATOM   5667  C C   . GLY B 2 321 ? 117.045 77.695  102.731 1.00 390.38 ? 321 GLY B C   1 
ATOM   5668  O O   . GLY B 2 321 ? 116.969 78.830  102.269 1.00 431.77 ? 321 GLY B O   1 
ATOM   5669  N N   . VAL B 2 322 ? 118.167 76.948  102.698 1.00 384.06 ? 322 VAL B N   1 
ATOM   5670  C CA  . VAL B 2 322 ? 119.471 77.426  102.235 1.00 374.71 ? 322 VAL B CA  1 
ATOM   5671  C C   . VAL B 2 322 ? 119.410 77.847  100.758 1.00 330.36 ? 322 VAL B C   1 
ATOM   5672  O O   . VAL B 2 322 ? 120.209 78.692  100.332 1.00 238.31 ? 322 VAL B O   1 
ATOM   5673  C CB  . VAL B 2 322 ? 120.572 76.363  102.485 1.00 430.27 ? 322 VAL B CB  1 
ATOM   5674  C CG1 . VAL B 2 322 ? 121.948 76.791  101.969 1.00 451.58 ? 322 VAL B CG1 1 
ATOM   5675  C CG2 . VAL B 2 322 ? 120.667 75.976  103.959 1.00 441.02 ? 322 VAL B CG2 1 
ATOM   5676  N N   . MET B 2 323 ? 118.466 77.265  99.987  1.00 314.25 ? 323 MET B N   1 
ATOM   5677  C CA  . MET B 2 323 ? 118.316 77.539  98.564  1.00 278.63 ? 323 MET B CA  1 
ATOM   5678  C C   . MET B 2 323 ? 117.214 78.571  98.262  1.00 284.30 ? 323 MET B C   1 
ATOM   5679  O O   . MET B 2 323 ? 116.876 78.754  97.096  1.00 295.75 ? 323 MET B O   1 
ATOM   5680  C CB  . MET B 2 323 ? 118.011 76.216  97.850  1.00 261.19 ? 323 MET B CB  1 
ATOM   5681  C CG  . MET B 2 323 ? 118.470 76.164  96.392  1.00 346.26 ? 323 MET B CG  1 
ATOM   5682  S SD  . MET B 2 323 ? 120.250 76.494  96.078  1.00 332.78 ? 323 MET B SD  1 
ATOM   5683  C CE  . MET B 2 323 ? 120.174 76.818  94.315  1.00 340.66 ? 323 MET B CE  1 
ATOM   5684  N N   . SER B 2 324 ? 116.667 79.288  99.266  1.00 307.98 ? 324 SER B N   1 
ATOM   5685  C CA  . SER B 2 324 ? 115.444 80.078  99.102  1.00 242.61 ? 324 SER B CA  1 
ATOM   5686  C C   . SER B 2 324 ? 115.587 81.288  98.179  1.00 211.84 ? 324 SER B C   1 
ATOM   5687  O O   . SER B 2 324 ? 114.556 81.821  97.779  1.00 257.51 ? 324 SER B O   1 
ATOM   5688  C CB  . SER B 2 324 ? 114.904 80.545  100.438 1.00 237.00 ? 324 SER B CB  1 
ATOM   5689  O OG  . SER B 2 324 ? 113.721 81.320  100.274 1.00 205.42 ? 324 SER B OG  1 
ATOM   5690  N N   . TRP B 2 325 ? 116.812 81.732  97.852  1.00 165.66 ? 325 TRP B N   1 
ATOM   5691  C CA  . TRP B 2 325 ? 116.994 82.960  97.072  1.00 222.64 ? 325 TRP B CA  1 
ATOM   5692  C C   . TRP B 2 325 ? 116.412 82.867  95.648  1.00 208.49 ? 325 TRP B C   1 
ATOM   5693  O O   . TRP B 2 325 ? 116.169 83.902  95.002  1.00 190.56 ? 325 TRP B O   1 
ATOM   5694  C CB  . TRP B 2 325 ? 118.477 83.378  97.040  1.00 234.27 ? 325 TRP B CB  1 
ATOM   5695  C CG  . TRP B 2 325 ? 119.376 82.310  96.480  1.00 236.32 ? 325 TRP B CG  1 
ATOM   5696  C CD1 . TRP B 2 325 ? 120.071 81.389  97.208  1.00 316.96 ? 325 TRP B CD1 1 
ATOM   5697  C CD2 . TRP B 2 325 ? 119.671 82.033  95.098  1.00 191.32 ? 325 TRP B CD2 1 
ATOM   5698  N NE1 . TRP B 2 325 ? 120.784 80.564  96.382  1.00 308.59 ? 325 TRP B NE1 1 
ATOM   5699  C CE2 . TRP B 2 325 ? 120.557 80.934  95.083  1.00 277.03 ? 325 TRP B CE2 1 
ATOM   5700  C CE3 . TRP B 2 325 ? 119.284 82.595  93.881  1.00 217.91 ? 325 TRP B CE3 1 
ATOM   5701  C CZ2 . TRP B 2 325 ? 121.053 80.396  93.896  1.00 378.93 ? 325 TRP B CZ2 1 
ATOM   5702  C CZ3 . TRP B 2 325 ? 119.772 82.064  92.707  1.00 336.30 ? 325 TRP B CZ3 1 
ATOM   5703  C CH2 . TRP B 2 325 ? 120.646 80.977  92.714  1.00 391.45 ? 325 TRP B CH2 1 
ATOM   5704  N N   . ILE B 2 326 ? 116.169 81.649  95.143  1.00 176.87 ? 326 ILE B N   1 
ATOM   5705  C CA  . ILE B 2 326 ? 115.638 81.497  93.797  1.00 206.25 ? 326 ILE B CA  1 
ATOM   5706  C C   . ILE B 2 326 ? 114.243 82.119  93.630  1.00 200.99 ? 326 ILE B C   1 
ATOM   5707  O O   . ILE B 2 326 ? 113.960 82.640  92.543  1.00 263.76 ? 326 ILE B O   1 
ATOM   5708  C CB  . ILE B 2 326 ? 115.640 80.019  93.366  1.00 278.13 ? 326 ILE B CB  1 
ATOM   5709  C CG1 . ILE B 2 326 ? 114.601 79.168  94.123  1.00 302.79 ? 326 ILE B CG1 1 
ATOM   5710  C CG2 . ILE B 2 326 ? 117.072 79.461  93.444  1.00 290.81 ? 326 ILE B CG2 1 
ATOM   5711  C CD1 . ILE B 2 326 ? 114.511 77.733  93.634  1.00 376.60 ? 326 ILE B CD1 1 
ATOM   5712  N N   . ILE B 2 327 ? 113.373 82.056  94.654  1.00 160.76 ? 327 ILE B N   1 
ATOM   5713  C CA  . ILE B 2 327 ? 112.010 82.561  94.501  1.00 199.57 ? 327 ILE B CA  1 
ATOM   5714  C C   . ILE B 2 327 ? 111.993 84.092  94.383  1.00 185.90 ? 327 ILE B C   1 
ATOM   5715  O O   . ILE B 2 327 ? 111.372 84.588  93.440  1.00 289.35 ? 327 ILE B O   1 
ATOM   5716  C CB  . ILE B 2 327 ? 111.050 82.026  95.588  1.00 214.73 ? 327 ILE B CB  1 
ATOM   5717  C CG1 . ILE B 2 327 ? 110.925 80.501  95.461  1.00 248.87 ? 327 ILE B CG1 1 
ATOM   5718  C CG2 . ILE B 2 327 ? 109.687 82.746  95.575  1.00 148.71 ? 327 ILE B CG2 1 
ATOM   5719  C CD1 . ILE B 2 327 ? 110.302 79.997  94.163  1.00 238.43 ? 327 ILE B CD1 1 
ATOM   5720  N N   . PRO B 2 328 ? 112.625 84.888  95.271  1.00 153.90 ? 328 PRO B N   1 
ATOM   5721  C CA  . PRO B 2 328 ? 112.782 86.321  95.028  1.00 155.55 ? 328 PRO B CA  1 
ATOM   5722  C C   . PRO B 2 328 ? 113.299 86.650  93.628  1.00 191.59 ? 328 PRO B C   1 
ATOM   5723  O O   . PRO B 2 328 ? 112.711 87.513  92.975  1.00 244.58 ? 328 PRO B O   1 
ATOM   5724  C CB  . PRO B 2 328 ? 113.802 86.735  96.091  1.00 213.47 ? 328 PRO B CB  1 
ATOM   5725  C CG  . PRO B 2 328 ? 113.531 85.785  97.233  1.00 267.71 ? 328 PRO B CG  1 
ATOM   5726  C CD  . PRO B 2 328 ? 113.187 84.476  96.562  1.00 220.79 ? 328 PRO B CD  1 
ATOM   5727  N N   . VAL B 2 329 ? 114.363 85.973  93.147  1.00 153.15 ? 329 VAL B N   1 
ATOM   5728  C CA  . VAL B 2 329 ? 114.909 86.318  91.840  1.00 145.56 ? 329 VAL B CA  1 
ATOM   5729  C C   . VAL B 2 329 ? 113.884 86.057  90.734  1.00 160.02 ? 329 VAL B C   1 
ATOM   5730  O O   . VAL B 2 329 ? 113.720 86.914  89.882  1.00 210.80 ? 329 VAL B O   1 
ATOM   5731  C CB  . VAL B 2 329 ? 116.253 85.627  91.584  1.00 176.39 ? 329 VAL B CB  1 
ATOM   5732  C CG1 . VAL B 2 329 ? 116.655 85.562  90.114  1.00 239.38 ? 329 VAL B CG1 1 
ATOM   5733  C CG2 . VAL B 2 329 ? 117.340 86.327  92.380  1.00 185.59 ? 329 VAL B CG2 1 
ATOM   5734  N N   . PHE B 2 330 ? 113.178 84.931  90.746  1.00 172.85 ? 330 PHE B N   1 
ATOM   5735  C CA  . PHE B 2 330 ? 112.135 84.709  89.748  1.00 210.86 ? 330 PHE B CA  1 
ATOM   5736  C C   . PHE B 2 330 ? 110.944 85.686  89.827  1.00 188.37 ? 330 PHE B C   1 
ATOM   5737  O O   . PHE B 2 330 ? 110.388 86.006  88.787  1.00 168.95 ? 330 PHE B O   1 
ATOM   5738  C CB  . PHE B 2 330 ? 111.582 83.293  89.866  1.00 271.52 ? 330 PHE B CB  1 
ATOM   5739  C CG  . PHE B 2 330 ? 112.465 82.182  89.354  1.00 285.97 ? 330 PHE B CG  1 
ATOM   5740  C CD1 . PHE B 2 330 ? 113.120 82.282  88.136  1.00 313.70 ? 330 PHE B CD1 1 
ATOM   5741  C CD2 . PHE B 2 330 ? 112.628 81.015  90.087  1.00 355.48 ? 330 PHE B CD2 1 
ATOM   5742  C CE1 . PHE B 2 330 ? 113.930 81.251  87.674  1.00 374.45 ? 330 PHE B CE1 1 
ATOM   5743  C CE2 . PHE B 2 330 ? 113.435 79.983  89.622  1.00 374.74 ? 330 PHE B CE2 1 
ATOM   5744  C CZ  . PHE B 2 330 ? 114.086 80.101  88.415  1.00 351.54 ? 330 PHE B CZ  1 
ATOM   5745  N N   . VAL B 2 331 ? 110.528 86.174  91.008  1.00 177.66 ? 331 VAL B N   1 
ATOM   5746  C CA  . VAL B 2 331 ? 109.535 87.247  91.072  1.00 155.41 ? 331 VAL B CA  1 
ATOM   5747  C C   . VAL B 2 331 ? 110.082 88.499  90.384  1.00 169.76 ? 331 VAL B C   1 
ATOM   5748  O O   . VAL B 2 331 ? 109.331 89.215  89.722  1.00 184.69 ? 331 VAL B O   1 
ATOM   5749  C CB  . VAL B 2 331 ? 109.099 87.602  92.507  1.00 181.36 ? 331 VAL B CB  1 
ATOM   5750  C CG1 . VAL B 2 331 ? 108.160 88.815  92.563  1.00 149.79 ? 331 VAL B CG1 1 
ATOM   5751  C CG2 . VAL B 2 331 ? 108.461 86.385  93.145  1.00 243.38 ? 331 VAL B CG2 1 
ATOM   5752  N N   . GLY B 2 332 ? 111.387 88.761  90.549  1.00 158.85 ? 332 GLY B N   1 
ATOM   5753  C CA  . GLY B 2 332 ? 112.061 89.818  89.818  1.00 166.81 ? 332 GLY B CA  1 
ATOM   5754  C C   . GLY B 2 332 ? 111.945 89.624  88.311  1.00 177.98 ? 332 GLY B C   1 
ATOM   5755  O O   . GLY B 2 332 ? 111.415 90.481  87.616  1.00 173.83 ? 332 GLY B O   1 
ATOM   5756  N N   . LEU B 2 333 ? 112.421 88.480  87.820  1.00 172.38 ? 333 LEU B N   1 
ATOM   5757  C CA  . LEU B 2 333 ? 112.391 88.176  86.399  1.00 160.24 ? 333 LEU B CA  1 
ATOM   5758  C C   . LEU B 2 333 ? 110.963 88.164  85.842  1.00 142.80 ? 333 LEU B C   1 
ATOM   5759  O O   . LEU B 2 333 ? 110.772 88.476  84.668  1.00 147.38 ? 333 LEU B O   1 
ATOM   5760  C CB  . LEU B 2 333 ? 113.126 86.847  86.188  1.00 166.30 ? 333 LEU B CB  1 
ATOM   5761  C CG  . LEU B 2 333 ? 114.609 86.891  86.584  1.00 230.18 ? 333 LEU B CG  1 
ATOM   5762  C CD1 . LEU B 2 333 ? 115.289 85.591  86.160  1.00 290.44 ? 333 LEU B CD1 1 
ATOM   5763  C CD2 . LEU B 2 333 ? 115.352 88.154  86.040  1.00 182.10 ? 333 LEU B CD2 1 
ATOM   5764  N N   . SER B 2 334 ? 109.970 87.828  86.663  1.00 129.10 ? 334 SER B N   1 
ATOM   5765  C CA  . SER B 2 334 ? 108.581 87.908  86.238  1.00 169.18 ? 334 SER B CA  1 
ATOM   5766  C C   . SER B 2 334 ? 108.118 89.340  86.014  1.00 131.68 ? 334 SER B C   1 
ATOM   5767  O O   . SER B 2 334 ? 107.308 89.572  85.121  1.00 208.56 ? 334 SER B O   1 
ATOM   5768  C CB  . SER B 2 334 ? 107.667 87.242  87.221  1.00 220.26 ? 334 SER B CB  1 
ATOM   5769  O OG  . SER B 2 334 ? 106.340 87.219  86.709  1.00 168.66 ? 334 SER B OG  1 
ATOM   5770  N N   . CYS B 2 335 ? 108.592 90.281  86.824  1.00 140.54 ? 335 CYS B N   1 
ATOM   5771  C CA  . CYS B 2 335 ? 108.237 91.682  86.651  1.00 179.54 ? 335 CYS B CA  1 
ATOM   5772  C C   . CYS B 2 335 ? 108.938 92.239  85.418  1.00 171.69 ? 335 CYS B C   1 
ATOM   5773  O O   . CYS B 2 335 ? 108.328 92.989  84.673  1.00 177.72 ? 335 CYS B O   1 
ATOM   5774  C CB  . CYS B 2 335 ? 108.589 92.467  87.905  1.00 209.66 ? 335 CYS B CB  1 
ATOM   5775  S SG  . CYS B 2 335 ? 107.652 91.910  89.349  1.00 192.67 ? 335 CYS B SG  1 
ATOM   5776  N N   . PHE B 2 336 ? 110.201 91.843  85.207  1.00 147.27 ? 336 PHE B N   1 
ATOM   5777  C CA  . PHE B 2 336 ? 111.022 92.381  84.134  1.00 142.70 ? 336 PHE B CA  1 
ATOM   5778  C C   . PHE B 2 336 ? 110.382 92.135  82.776  1.00 155.60 ? 336 PHE B C   1 
ATOM   5779  O O   . PHE B 2 336 ? 110.265 93.091  82.012  1.00 119.81 ? 336 PHE B O   1 
ATOM   5780  C CB  . PHE B 2 336 ? 112.387 91.736  84.237  1.00 170.11 ? 336 PHE B CB  1 
ATOM   5781  C CG  . PHE B 2 336 ? 113.449 92.291  83.341  1.00 166.05 ? 336 PHE B CG  1 
ATOM   5782  C CD1 . PHE B 2 336 ? 114.155 93.440  83.713  1.00 137.94 ? 336 PHE B CD1 1 
ATOM   5783  C CD2 . PHE B 2 336 ? 113.751 91.634  82.157  1.00 165.35 ? 336 PHE B CD2 1 
ATOM   5784  C CE1 . PHE B 2 336 ? 115.159 93.923  82.888  1.00 196.12 ? 336 PHE B CE1 1 
ATOM   5785  C CE2 . PHE B 2 336 ? 114.755 92.125  81.335  1.00 217.78 ? 336 PHE B CE2 1 
ATOM   5786  C CZ  . PHE B 2 336 ? 115.451 93.262  81.702  1.00 253.21 ? 336 PHE B CZ  1 
ATOM   5787  N N   . GLY B 2 337 ? 109.953 90.880  82.527  1.00 146.94 ? 337 GLY B N   1 
ATOM   5788  C CA  . GLY B 2 337 ? 109.097 90.478  81.399  1.00 157.53 ? 337 GLY B CA  1 
ATOM   5789  C C   . GLY B 2 337 ? 107.876 91.364  81.081  1.00 136.09 ? 337 GLY B C   1 
ATOM   5790  O O   . GLY B 2 337 ? 107.549 91.627  79.914  1.00 189.93 ? 337 GLY B O   1 
ATOM   5791  N N   . SER B 2 338 ? 107.213 91.837  82.128  1.00 121.69 ? 338 SER B N   1 
ATOM   5792  C CA  . SER B 2 338 ? 106.057 92.704  82.005  1.00 141.88 ? 338 SER B CA  1 
ATOM   5793  C C   . SER B 2 338 ? 106.461 94.149  81.682  1.00 161.62 ? 338 SER B C   1 
ATOM   5794  O O   . SER B 2 338 ? 105.704 94.843  80.995  1.00 138.12 ? 338 SER B O   1 
ATOM   5795  C CB  . SER B 2 338 ? 105.221 92.641  83.256  1.00 165.71 ? 338 SER B CB  1 
ATOM   5796  O OG  . SER B 2 338 ? 104.105 93.531  83.174  1.00 180.36 ? 338 SER B OG  1 
ATOM   5797  N N   . VAL B 2 339 ? 107.623 94.625  82.175  1.00 126.96 ? 339 VAL B N   1 
ATOM   5798  C CA  . VAL B 2 339 ? 108.037 95.974  81.850  1.00 126.02 ? 339 VAL B CA  1 
ATOM   5799  C C   . VAL B 2 339 ? 108.242 96.019  80.346  1.00 154.62 ? 339 VAL B C   1 
ATOM   5800  O O   . VAL B 2 339 ? 107.895 97.016  79.704  1.00 216.67 ? 339 VAL B O   1 
ATOM   5801  C CB  . VAL B 2 339 ? 109.302 96.432  82.598  1.00 140.55 ? 339 VAL B CB  1 
ATOM   5802  C CG1 . VAL B 2 339 ? 109.752 97.826  82.140  1.00 192.00 ? 339 VAL B CG1 1 
ATOM   5803  C CG2 . VAL B 2 339 ? 109.109 96.432  84.100  1.00 166.10 ? 339 VAL B CG2 1 
ATOM   5804  N N   . ASN B 2 340 ? 108.819 94.939  79.804  1.00 131.10 ? 340 ASN B N   1 
ATOM   5805  C CA  . ASN B 2 340 ? 109.088 94.859  78.382  1.00 138.38 ? 340 ASN B CA  1 
ATOM   5806  C C   . ASN B 2 340 ? 107.769 94.864  77.608  1.00 129.43 ? 340 ASN B C   1 
ATOM   5807  O O   . ASN B 2 340 ? 107.587 95.695  76.717  1.00 91.22  ? 340 ASN B O   1 
ATOM   5808  C CB  . ASN B 2 340 ? 109.955 93.635  78.132  1.00 148.65 ? 340 ASN B CB  1 
ATOM   5809  C CG  . ASN B 2 340 ? 110.166 93.398  76.674  1.00 168.83 ? 340 ASN B CG  1 
ATOM   5810  O OD1 . ASN B 2 340 ? 110.410 94.372  75.960  1.00 226.85 ? 340 ASN B OD1 1 
ATOM   5811  N ND2 . ASN B 2 340 ? 110.071 92.139  76.258  1.00 127.05 ? 340 ASN B ND2 1 
ATOM   5812  N N   . GLY B 2 341 ? 106.864 93.936  77.966  1.00 143.46 ? 341 GLY B N   1 
ATOM   5813  C CA  . GLY B 2 341 ? 105.558 93.803  77.337  1.00 145.87 ? 341 GLY B CA  1 
ATOM   5814  C C   . GLY B 2 341 ? 104.740 95.090  77.371  1.00 133.83 ? 341 GLY B C   1 
ATOM   5815  O O   . GLY B 2 341 ? 104.030 95.382  76.407  1.00 161.64 ? 341 GLY B O   1 
ATOM   5816  N N   . SER B 2 342 ? 104.855 95.857  78.457  1.00 96.84  ? 342 SER B N   1 
ATOM   5817  C CA  . SER B 2 342 ? 104.157 97.113  78.503  1.00 132.36 ? 342 SER B CA  1 
ATOM   5818  C C   . SER B 2 342 ? 104.885 98.154  77.655  1.00 132.47 ? 342 SER B C   1 
ATOM   5819  O O   . SER B 2 342 ? 104.192 98.890  76.962  1.00 147.61 ? 342 SER B O   1 
ATOM   5820  C CB  . SER B 2 342 ? 103.909 97.572  79.917  1.00 217.74 ? 342 SER B CB  1 
ATOM   5821  O OG  . SER B 2 342 ? 103.054 98.715  79.905  1.00 300.00 ? 342 SER B OG  1 
ATOM   5822  N N   . LEU B 2 343 ? 106.228 98.251  77.679  1.00 139.80 ? 343 LEU B N   1 
ATOM   5823  C CA  . LEU B 2 343 ? 106.899 99.237  76.830  1.00 140.30 ? 343 LEU B CA  1 
ATOM   5824  C C   . LEU B 2 343 ? 106.581 98.982  75.364  1.00 135.99 ? 343 LEU B C   1 
ATOM   5825  O O   . LEU B 2 343 ? 106.384 99.940  74.612  1.00 125.34 ? 343 LEU B O   1 
ATOM   5826  C CB  . LEU B 2 343 ? 108.418 99.218  77.048  1.00 152.94 ? 343 LEU B CB  1 
ATOM   5827  C CG  . LEU B 2 343 ? 108.885 99.977  78.283  1.00 200.44 ? 343 LEU B CG  1 
ATOM   5828  C CD1 . LEU B 2 343 ? 110.349 99.660  78.569  1.00 275.69 ? 343 LEU B CD1 1 
ATOM   5829  C CD2 . LEU B 2 343 ? 108.648 101.479 78.112  1.00 140.61 ? 343 LEU B CD2 1 
ATOM   5830  N N   . PHE B 2 344 ? 106.580 97.699  74.980  1.00 146.07 ? 344 PHE B N   1 
ATOM   5831  C CA  . PHE B 2 344 ? 106.193 97.260  73.649  1.00 144.97 ? 344 PHE B CA  1 
ATOM   5832  C C   . PHE B 2 344 ? 104.820 97.815  73.319  1.00 129.21 ? 344 PHE B C   1 
ATOM   5833  O O   . PHE B 2 344 ? 104.710 98.630  72.429  1.00 136.79 ? 344 PHE B O   1 
ATOM   5834  C CB  . PHE B 2 344 ? 106.214 95.738  73.607  1.00 176.95 ? 344 PHE B CB  1 
ATOM   5835  C CG  . PHE B 2 344 ? 106.279 95.067  72.265  1.00 169.17 ? 344 PHE B CG  1 
ATOM   5836  C CD1 . PHE B 2 344 ? 105.319 95.294  71.301  1.00 153.42 ? 344 PHE B CD1 1 
ATOM   5837  C CD2 . PHE B 2 344 ? 107.305 94.164  72.002  1.00 185.50 ? 344 PHE B CD2 1 
ATOM   5838  C CE1 . PHE B 2 344 ? 105.408 94.643  70.084  1.00 210.74 ? 344 PHE B CE1 1 
ATOM   5839  C CE2 . PHE B 2 344 ? 107.394 93.512  70.795  1.00 192.58 ? 344 PHE B CE2 1 
ATOM   5840  C CZ  . PHE B 2 344 ? 106.435 93.749  69.837  1.00 249.94 ? 344 PHE B CZ  1 
ATOM   5841  N N   . THR B 2 345 ? 103.786 97.390  74.039  1.00 116.84 ? 345 THR B N   1 
ATOM   5842  C CA  . THR B 2 345 ? 102.434 97.731  73.650  1.00 158.04 ? 345 THR B CA  1 
ATOM   5843  C C   . THR B 2 345 ? 102.076 99.204  73.921  1.00 146.43 ? 345 THR B C   1 
ATOM   5844  O O   . THR B 2 345 ? 101.164 99.726  73.272  1.00 187.22 ? 345 THR B O   1 
ATOM   5845  C CB  . THR B 2 345 ? 101.443 96.774  74.323  1.00 193.26 ? 345 THR B CB  1 
ATOM   5846  O OG1 . THR B 2 345 ? 101.601 96.868  75.738  1.00 205.68 ? 345 THR B OG1 1 
ATOM   5847  C CG2 . THR B 2 345 ? 101.645 95.344  73.869  1.00 177.85 ? 345 THR B CG2 1 
ATOM   5848  N N   . SER B 2 346 ? 102.744 99.865  74.867  1.00 141.95 ? 346 SER B N   1 
ATOM   5849  C CA  . SER B 2 346 ? 102.469 101.260 75.166  1.00 164.73 ? 346 SER B CA  1 
ATOM   5850  C C   . SER B 2 346 ? 102.998 102.155 74.049  1.00 157.91 ? 346 SER B C   1 
ATOM   5851  O O   . SER B 2 346 ? 102.309 103.071 73.620  1.00 159.92 ? 346 SER B O   1 
ATOM   5852  C CB  . SER B 2 346 ? 103.052 101.656 76.493  1.00 184.71 ? 346 SER B CB  1 
ATOM   5853  O OG  . SER B 2 346 ? 102.794 103.025 76.775  1.00 194.91 ? 346 SER B OG  1 
ATOM   5854  N N   . SER B 2 347 ? 104.220 101.897 73.576  1.00 130.26 ? 347 SER B N   1 
ATOM   5855  C CA  . SER B 2 347 ? 104.768 102.695 72.483  1.00 182.09 ? 347 SER B CA  1 
ATOM   5856  C C   . SER B 2 347 ? 103.899 102.618 71.224  1.00 177.12 ? 347 SER B C   1 
ATOM   5857  O O   . SER B 2 347 ? 103.741 103.599 70.503  1.00 152.35 ? 347 SER B O   1 
ATOM   5858  C CB  . SER B 2 347 ? 106.192 102.308 72.175  1.00 173.91 ? 347 SER B CB  1 
ATOM   5859  O OG  . SER B 2 347 ? 106.279 100.947 71.809  1.00 168.24 ? 347 SER B OG  1 
ATOM   5860  N N   . ARG B 2 348 ? 103.326 101.449 70.943  1.00 146.34 ? 348 ARG B N   1 
ATOM   5861  C CA  . ARG B 2 348 ? 102.471 101.316 69.783  1.00 128.09 ? 348 ARG B CA  1 
ATOM   5862  C C   . ARG B 2 348 ? 101.166 102.098 69.938  1.00 115.69 ? 348 ARG B C   1 
ATOM   5863  O O   . ARG B 2 348 ? 100.679 102.611 68.933  1.00 149.14 ? 348 ARG B O   1 
ATOM   5864  C CB  . ARG B 2 348 ? 102.152 99.844  69.519  1.00 157.98 ? 348 ARG B CB  1 
ATOM   5865  C CG  . ARG B 2 348 ? 103.370 98.975  69.255  1.00 148.26 ? 348 ARG B CG  1 
ATOM   5866  C CD  . ARG B 2 348 ? 104.562 99.622  68.561  1.00 135.22 ? 348 ARG B CD  1 
ATOM   5867  N NE  . ARG B 2 348 ? 105.430 98.531  68.130  1.00 202.17 ? 348 ARG B NE  1 
ATOM   5868  C CZ  . ARG B 2 348 ? 106.611 98.162  68.642  1.00 189.14 ? 348 ARG B CZ  1 
ATOM   5869  N NH1 . ARG B 2 348 ? 107.288 97.197  68.046  1.00 164.71 ? 348 ARG B NH1 1 
ATOM   5870  N NH2 . ARG B 2 348 ? 107.126 98.743  69.712  1.00 150.00 ? 348 ARG B NH2 1 
ATOM   5871  N N   . LEU B 2 349 ? 100.592 102.186 71.149  1.00 136.58 ? 349 LEU B N   1 
ATOM   5872  C CA  . LEU B 2 349 ? 99.411  103.013 71.376  1.00 143.78 ? 349 LEU B CA  1 
ATOM   5873  C C   . LEU B 2 349 ? 99.704  104.462 70.964  1.00 145.03 ? 349 LEU B C   1 
ATOM   5874  O O   . LEU B 2 349 ? 98.935  105.017 70.174  1.00 151.18 ? 349 LEU B O   1 
ATOM   5875  C CB  . LEU B 2 349 ? 98.938  102.957 72.839  1.00 173.31 ? 349 LEU B CB  1 
ATOM   5876  C CG  . LEU B 2 349 ? 98.003  104.118 73.239  1.00 183.62 ? 349 LEU B CG  1 
ATOM   5877  C CD1 . LEU B 2 349 ? 96.649  103.934 72.571  1.00 240.23 ? 349 LEU B CD1 1 
ATOM   5878  C CD2 . LEU B 2 349 ? 97.823  104.288 74.739  1.00 149.23 ? 349 LEU B CD2 1 
ATOM   5879  N N   . PHE B 2 350 ? 100.786 105.070 71.491  1.00 140.20 ? 350 PHE B N   1 
ATOM   5880  C CA  . PHE B 2 350 ? 101.064 106.476 71.238  1.00 184.13 ? 350 PHE B CA  1 
ATOM   5881  C C   . PHE B 2 350 ? 101.366 106.704 69.755  1.00 175.35 ? 350 PHE B C   1 
ATOM   5882  O O   . PHE B 2 350 ? 100.977 107.744 69.205  1.00 209.34 ? 350 PHE B O   1 
ATOM   5883  C CB  . PHE B 2 350 ? 102.178 106.984 72.161  1.00 206.16 ? 350 PHE B CB  1 
ATOM   5884  C CG  . PHE B 2 350 ? 101.922 106.867 73.645  1.00 229.13 ? 350 PHE B CG  1 
ATOM   5885  C CD1 . PHE B 2 350 ? 100.637 106.825 74.179  1.00 237.12 ? 350 PHE B CD1 1 
ATOM   5886  C CD2 . PHE B 2 350 ? 102.984 106.795 74.527  1.00 242.59 ? 350 PHE B CD2 1 
ATOM   5887  C CE1 . PHE B 2 350 ? 100.422 106.720 75.551  1.00 204.98 ? 350 PHE B CE1 1 
ATOM   5888  C CE2 . PHE B 2 350 ? 102.767 106.682 75.897  1.00 282.63 ? 350 PHE B CE2 1 
ATOM   5889  C CZ  . PHE B 2 350 ? 101.490 106.645 76.409  1.00 249.38 ? 350 PHE B CZ  1 
ATOM   5890  N N   . PHE B 2 351 ? 102.048 105.744 69.123  1.00 124.57 ? 351 PHE B N   1 
ATOM   5891  C CA  . PHE B 2 351 ? 102.287 105.773 67.676  1.00 183.60 ? 351 PHE B CA  1 
ATOM   5892  C C   . PHE B 2 351 ? 101.007 105.871 66.844  1.00 146.96 ? 351 PHE B C   1 
ATOM   5893  O O   . PHE B 2 351 ? 100.932 106.694 65.933  1.00 164.19 ? 351 PHE B O   1 
ATOM   5894  C CB  . PHE B 2 351 ? 103.111 104.545 67.334  1.00 241.01 ? 351 PHE B CB  1 
ATOM   5895  C CG  . PHE B 2 351 ? 103.220 104.113 65.901  1.00 222.37 ? 351 PHE B CG  1 
ATOM   5896  C CD1 . PHE B 2 351 ? 104.108 104.745 65.046  1.00 242.43 ? 351 PHE B CD1 1 
ATOM   5897  C CD2 . PHE B 2 351 ? 102.463 103.047 65.442  1.00 202.85 ? 351 PHE B CD2 1 
ATOM   5898  C CE1 . PHE B 2 351 ? 104.216 104.316 63.737  1.00 271.81 ? 351 PHE B CE1 1 
ATOM   5899  C CE2 . PHE B 2 351 ? 102.580 102.624 64.133  1.00 259.30 ? 351 PHE B CE2 1 
ATOM   5900  C CZ  . PHE B 2 351 ? 103.459 103.255 63.285  1.00 296.13 ? 351 PHE B CZ  1 
ATOM   5901  N N   . VAL B 2 352 ? 100.010 105.066 67.202  1.00 142.63 ? 352 VAL B N   1 
ATOM   5902  C CA  . VAL B 2 352 ? 98.688  105.178 66.605  1.00 170.97 ? 352 VAL B CA  1 
ATOM   5903  C C   . VAL B 2 352 ? 98.005  106.514 66.949  1.00 167.77 ? 352 VAL B C   1 
ATOM   5904  O O   . VAL B 2 352 ? 97.431  107.146 66.070  1.00 205.09 ? 352 VAL B O   1 
ATOM   5905  C CB  . VAL B 2 352 ? 97.809  103.983 67.014  1.00 200.14 ? 352 VAL B CB  1 
ATOM   5906  C CG1 . VAL B 2 352 ? 96.329  104.180 66.680  1.00 213.56 ? 352 VAL B CG1 1 
ATOM   5907  C CG2 . VAL B 2 352 ? 98.347  102.706 66.391  1.00 186.51 ? 352 VAL B CG2 1 
ATOM   5908  N N   . GLY B 2 353 ? 98.039  106.953 68.206  1.00 165.43 ? 353 GLY B N   1 
ATOM   5909  C CA  . GLY B 2 353 ? 97.433  108.220 68.592  1.00 185.94 ? 353 GLY B CA  1 
ATOM   5910  C C   . GLY B 2 353 ? 98.034  109.426 67.875  1.00 196.04 ? 353 GLY B C   1 
ATOM   5911  O O   . GLY B 2 353 ? 97.339  110.424 67.688  1.00 246.36 ? 353 GLY B O   1 
ATOM   5912  N N   . SER B 2 354 ? 99.306  109.326 67.468  1.00 177.79 ? 354 SER B N   1 
ATOM   5913  C CA  . SER B 2 354 ? 99.921  110.368 66.657  1.00 227.28 ? 354 SER B CA  1 
ATOM   5914  C C   . SER B 2 354 ? 99.537  110.246 65.177  1.00 232.96 ? 354 SER B C   1 
ATOM   5915  O O   . SER B 2 354 ? 99.257  111.270 64.545  1.00 194.53 ? 354 SER B O   1 
ATOM   5916  C CB  . SER B 2 354 ? 101.405 110.356 66.860  1.00 251.32 ? 354 SER B CB  1 
ATOM   5917  O OG  . SER B 2 354 ? 102.023 111.455 66.211  1.00 178.17 ? 354 SER B OG  1 
ATOM   5918  N N   . ARG B 2 355 ? 99.522  109.015 64.635  1.00 235.10 ? 355 ARG B N   1 
ATOM   5919  C CA  . ARG B 2 355 ? 99.080  108.744 63.270  1.00 213.23 ? 355 ARG B CA  1 
ATOM   5920  C C   . ARG B 2 355 ? 97.677  109.316 63.029  1.00 214.16 ? 355 ARG B C   1 
ATOM   5921  O O   . ARG B 2 355 ? 97.458  109.978 62.014  1.00 251.01 ? 355 ARG B O   1 
ATOM   5922  C CB  . ARG B 2 355 ? 99.132  107.234 63.014  1.00 227.36 ? 355 ARG B CB  1 
ATOM   5923  C CG  . ARG B 2 355 ? 98.583  106.770 61.669  1.00 268.19 ? 355 ARG B CG  1 
ATOM   5924  C CD  . ARG B 2 355 ? 97.864  105.431 61.749  1.00 303.09 ? 355 ARG B CD  1 
ATOM   5925  N NE  . ARG B 2 355 ? 98.773  104.296 61.883  1.00 301.83 ? 355 ARG B NE  1 
ATOM   5926  C CZ  . ARG B 2 355 ? 98.407  103.017 61.984  1.00 326.98 ? 355 ARG B CZ  1 
ATOM   5927  N NH1 . ARG B 2 355 ? 99.282  102.070 61.699  1.00 388.82 ? 355 ARG B NH1 1 
ATOM   5928  N NH2 . ARG B 2 355 ? 97.178  102.674 62.340  1.00 302.74 ? 355 ARG B NH2 1 
ATOM   5929  N N   . GLU B 2 356 ? 96.741  109.068 63.961  1.00 209.04 ? 356 GLU B N   1 
ATOM   5930  C CA  . GLU B 2 356 ? 95.353  109.504 63.824  1.00 243.44 ? 356 GLU B CA  1 
ATOM   5931  C C   . GLU B 2 356 ? 95.094  110.825 64.562  1.00 220.82 ? 356 GLU B C   1 
ATOM   5932  O O   . GLU B 2 356 ? 93.978  111.067 65.033  1.00 175.64 ? 356 GLU B O   1 
ATOM   5933  C CB  . GLU B 2 356 ? 94.425  108.379 64.292  1.00 291.80 ? 356 GLU B CB  1 
ATOM   5934  C CG  . GLU B 2 356 ? 94.689  107.068 63.567  1.00 344.01 ? 356 GLU B CG  1 
ATOM   5935  C CD  . GLU B 2 356 ? 93.584  106.026 63.630  1.00 394.32 ? 356 GLU B CD  1 
ATOM   5936  O OE1 . GLU B 2 356 ? 93.036  105.806 64.732  1.00 427.10 ? 356 GLU B OE1 1 
ATOM   5937  O OE2 . GLU B 2 356 ? 93.283  105.431 62.575  1.00 393.07 ? 356 GLU B OE2 1 
ATOM   5938  N N   . GLY B 2 357 ? 96.133  111.675 64.657  1.00 210.20 ? 357 GLY B N   1 
ATOM   5939  C CA  . GLY B 2 357 ? 95.984  113.121 64.672  1.00 245.36 ? 357 GLY B CA  1 
ATOM   5940  C C   . GLY B 2 357 ? 95.770  113.735 66.054  1.00 246.27 ? 357 GLY B C   1 
ATOM   5941  O O   . GLY B 2 357 ? 95.583  114.951 66.132  1.00 308.33 ? 357 GLY B O   1 
ATOM   5942  N N   . HIS B 2 358 ? 95.802  112.913 67.118  1.00 219.42 ? 358 HIS B N   1 
ATOM   5943  C CA  . HIS B 2 358 ? 95.538  113.363 68.483  1.00 261.79 ? 358 HIS B CA  1 
ATOM   5944  C C   . HIS B 2 358 ? 96.805  113.799 69.215  1.00 267.74 ? 358 HIS B C   1 
ATOM   5945  O O   . HIS B 2 358 ? 96.699  114.517 70.220  1.00 186.40 ? 358 HIS B O   1 
ATOM   5946  C CB  . HIS B 2 358 ? 94.795  112.274 69.270  1.00 237.81 ? 358 HIS B CB  1 
ATOM   5947  C CG  . HIS B 2 358 ? 93.324  112.290 69.023  1.00 247.66 ? 358 HIS B CG  1 
ATOM   5948  N ND1 . HIS B 2 358 ? 92.472  111.273 69.385  1.00 277.48 ? 358 HIS B ND1 1 
ATOM   5949  C CD2 . HIS B 2 358 ? 92.556  113.226 68.431  1.00 255.20 ? 358 HIS B CD2 1 
ATOM   5950  C CE1 . HIS B 2 358 ? 91.239  111.598 69.016  1.00 320.81 ? 358 HIS B CE1 1 
ATOM   5951  N NE2 . HIS B 2 358 ? 91.273  112.777 68.436  1.00 285.72 ? 358 HIS B NE2 1 
ATOM   5952  N N   . LEU B 2 359 ? 97.977  113.378 68.708  1.00 243.35 ? 359 LEU B N   1 
ATOM   5953  C CA  . LEU B 2 359 ? 99.208  113.505 69.463  1.00 253.47 ? 359 LEU B CA  1 
ATOM   5954  C C   . LEU B 2 359 ? 100.328 114.007 68.541  1.00 254.88 ? 359 LEU B C   1 
ATOM   5955  O O   . LEU B 2 359 ? 100.453 113.522 67.422  1.00 254.82 ? 359 LEU B O   1 
ATOM   5956  C CB  . LEU B 2 359 ? 99.441  112.116 70.071  1.00 243.30 ? 359 LEU B CB  1 
ATOM   5957  C CG  . LEU B 2 359 ? 100.279 112.029 71.340  1.00 307.43 ? 359 LEU B CG  1 
ATOM   5958  C CD1 . LEU B 2 359 ? 99.611  112.719 72.529  1.00 358.48 ? 359 LEU B CD1 1 
ATOM   5959  C CD2 . LEU B 2 359 ? 100.553 110.556 71.663  1.00 264.80 ? 359 LEU B CD2 1 
ATOM   5960  N N   . PRO B 2 360 ? 101.171 114.991 68.983  1.00 260.87 ? 360 PRO B N   1 
ATOM   5961  C CA  . PRO B 2 360 ? 102.159 115.679 68.128  1.00 235.46 ? 360 PRO B CA  1 
ATOM   5962  C C   . PRO B 2 360 ? 103.048 114.786 67.253  1.00 197.02 ? 360 PRO B C   1 
ATOM   5963  O O   . PRO B 2 360 ? 103.436 113.688 67.641  1.00 189.09 ? 360 PRO B O   1 
ATOM   5964  C CB  . PRO B 2 360 ? 103.062 116.450 69.109  1.00 272.31 ? 360 PRO B CB  1 
ATOM   5965  C CG  . PRO B 2 360 ? 102.666 115.961 70.487  1.00 317.27 ? 360 PRO B CG  1 
ATOM   5966  C CD  . PRO B 2 360 ? 101.229 115.504 70.361  1.00 281.38 ? 360 PRO B CD  1 
ATOM   5967  N N   . SER B 2 361 ? 103.355 115.286 66.050  1.00 218.27 ? 361 SER B N   1 
ATOM   5968  C CA  . SER B 2 361 ? 103.570 114.449 64.871  1.00 258.86 ? 361 SER B CA  1 
ATOM   5969  C C   . SER B 2 361 ? 104.802 113.548 64.996  1.00 212.46 ? 361 SER B C   1 
ATOM   5970  O O   . SER B 2 361 ? 104.840 112.457 64.424  1.00 160.43 ? 361 SER B O   1 
ATOM   5971  C CB  . SER B 2 361 ? 103.647 115.294 63.626  1.00 320.51 ? 361 SER B CB  1 
ATOM   5972  O OG  . SER B 2 361 ? 103.830 114.490 62.467  1.00 387.24 ? 361 SER B OG  1 
ATOM   5973  N N   . ILE B 2 362 ? 105.805 114.013 65.741  1.00 201.96 ? 362 ILE B N   1 
ATOM   5974  C CA  . ILE B 2 362 ? 107.064 113.299 65.888  1.00 204.93 ? 362 ILE B CA  1 
ATOM   5975  C C   . ILE B 2 362 ? 106.836 111.869 66.388  1.00 212.15 ? 362 ILE B C   1 
ATOM   5976  O O   . ILE B 2 362 ? 107.586 110.984 65.995  1.00 177.54 ? 362 ILE B O   1 
ATOM   5977  C CB  . ILE B 2 362 ? 108.048 114.133 66.758  1.00 244.85 ? 362 ILE B CB  1 
ATOM   5978  C CG1 . ILE B 2 362 ? 109.421 113.463 66.918  1.00 237.93 ? 362 ILE B CG1 1 
ATOM   5979  C CG2 . ILE B 2 362 ? 107.463 114.540 68.114  1.00 242.04 ? 362 ILE B CG2 1 
ATOM   5980  C CD1 . ILE B 2 362 ? 110.140 113.164 65.605  1.00 232.00 ? 362 ILE B CD1 1 
ATOM   5981  N N   . LEU B 2 363 ? 105.823 111.637 67.242  1.00 246.31 ? 363 LEU B N   1 
ATOM   5982  C CA  . LEU B 2 363 ? 105.586 110.318 67.832  1.00 247.93 ? 363 LEU B CA  1 
ATOM   5983  C C   . LEU B 2 363 ? 105.102 109.290 66.800  1.00 241.94 ? 363 LEU B C   1 
ATOM   5984  O O   . LEU B 2 363 ? 105.193 108.084 67.055  1.00 259.14 ? 363 LEU B O   1 
ATOM   5985  C CB  . LEU B 2 363 ? 104.585 110.455 68.991  1.00 215.38 ? 363 LEU B CB  1 
ATOM   5986  C CG  . LEU B 2 363 ? 105.015 111.346 70.169  1.00 253.68 ? 363 LEU B CG  1 
ATOM   5987  C CD1 . LEU B 2 363 ? 104.051 111.237 71.333  1.00 242.41 ? 363 LEU B CD1 1 
ATOM   5988  C CD2 . LEU B 2 363 ? 106.418 111.041 70.672  1.00 306.32 ? 363 LEU B CD2 1 
ATOM   5989  N N   . SER B 2 364 ? 104.586 109.739 65.643  1.00 185.03 ? 364 SER B N   1 
ATOM   5990  C CA  . SER B 2 364 ? 104.192 108.816 64.585  1.00 207.71 ? 364 SER B CA  1 
ATOM   5991  C C   . SER B 2 364 ? 105.383 108.297 63.773  1.00 208.67 ? 364 SER B C   1 
ATOM   5992  O O   . SER B 2 364 ? 105.200 107.398 62.950  1.00 228.37 ? 364 SER B O   1 
ATOM   5993  C CB  . SER B 2 364 ? 103.185 109.461 63.672  1.00 260.91 ? 364 SER B CB  1 
ATOM   5994  O OG  . SER B 2 364 ? 103.777 110.507 62.907  1.00 337.26 ? 364 SER B OG  1 
ATOM   5995  N N   . MET B 2 365 ? 106.587 108.854 63.973  1.00 177.40 ? 365 MET B N   1 
ATOM   5996  C CA  . MET B 2 365 ? 107.705 108.604 63.079  1.00 178.21 ? 365 MET B CA  1 
ATOM   5997  C C   . MET B 2 365 ? 108.418 107.315 63.464  1.00 154.89 ? 365 MET B C   1 
ATOM   5998  O O   . MET B 2 365 ? 108.221 106.788 64.553  1.00 197.68 ? 365 MET B O   1 
ATOM   5999  C CB  . MET B 2 365 ? 108.658 109.805 63.104  1.00 195.51 ? 365 MET B CB  1 
ATOM   6000  C CG  . MET B 2 365 ? 107.914 111.063 62.638  1.00 257.38 ? 365 MET B CG  1 
ATOM   6001  S SD  . MET B 2 365 ? 108.943 112.427 62.128  1.00 312.94 ? 365 MET B SD  1 
ATOM   6002  C CE  . MET B 2 365 ? 107.689 113.645 61.724  1.00 304.90 ? 365 MET B CE  1 
ATOM   6003  N N   . ILE B 2 366 ? 109.248 106.823 62.534  1.00 129.89 ? 366 ILE B N   1 
ATOM   6004  C CA  . ILE B 2 366 ? 109.937 105.546 62.641  1.00 156.73 ? 366 ILE B CA  1 
ATOM   6005  C C   . ILE B 2 366 ? 111.405 105.704 62.234  1.00 138.85 ? 366 ILE B C   1 
ATOM   6006  O O   . ILE B 2 366 ? 111.708 106.473 61.346  1.00 150.55 ? 366 ILE B O   1 
ATOM   6007  C CB  . ILE B 2 366 ? 109.231 104.515 61.736  1.00 166.42 ? 366 ILE B CB  1 
ATOM   6008  C CG1 . ILE B 2 366 ? 107.709 104.418 61.996  1.00 150.52 ? 366 ILE B CG1 1 
ATOM   6009  C CG2 . ILE B 2 366 ? 109.974 103.158 61.768  1.00 110.13 ? 366 ILE B CG2 1 
ATOM   6010  C CD1 . ILE B 2 366 ? 106.945 103.864 60.785  1.00 260.79 ? 366 ILE B CD1 1 
ATOM   6011  N N   . HIS B 2 367 ? 112.326 104.961 62.845  1.00 170.54 ? 367 HIS B N   1 
ATOM   6012  C CA  . HIS B 2 367 ? 113.719 104.971 62.429  1.00 203.72 ? 367 HIS B CA  1 
ATOM   6013  C C   . HIS B 2 367 ? 113.906 103.997 61.270  1.00 219.60 ? 367 HIS B C   1 
ATOM   6014  O O   . HIS B 2 367 ? 113.797 102.789 61.489  1.00 160.89 ? 367 HIS B O   1 
ATOM   6015  C CB  . HIS B 2 367 ? 114.623 104.586 63.599  1.00 290.57 ? 367 HIS B CB  1 
ATOM   6016  C CG  . HIS B 2 367 ? 116.069 104.529 63.219  1.00 268.87 ? 367 HIS B CG  1 
ATOM   6017  N ND1 . HIS B 2 367 ? 116.844 105.641 62.972  1.00 299.65 ? 367 HIS B ND1 1 
ATOM   6018  C CD2 . HIS B 2 367 ? 116.866 103.479 63.055  1.00 199.52 ? 367 HIS B CD2 1 
ATOM   6019  C CE1 . HIS B 2 367 ? 118.073 105.243 62.675  1.00 322.81 ? 367 HIS B CE1 1 
ATOM   6020  N NE2 . HIS B 2 367 ? 118.104 103.935 62.714  1.00 285.57 ? 367 HIS B NE2 1 
ATOM   6021  N N   . PRO B 2 368 ? 114.188 104.475 60.031  1.00 251.11 ? 368 PRO B N   1 
ATOM   6022  C CA  . PRO B 2 368 ? 114.019 103.650 58.832  1.00 270.63 ? 368 PRO B CA  1 
ATOM   6023  C C   . PRO B 2 368 ? 114.959 102.449 58.649  1.00 266.12 ? 368 PRO B C   1 
ATOM   6024  O O   . PRO B 2 368 ? 114.597 101.516 57.937  1.00 273.47 ? 368 PRO B O   1 
ATOM   6025  C CB  . PRO B 2 368 ? 114.238 104.647 57.684  1.00 246.28 ? 368 PRO B CB  1 
ATOM   6026  C CG  . PRO B 2 368 ? 115.122 105.711 58.274  1.00 231.54 ? 368 PRO B CG  1 
ATOM   6027  C CD  . PRO B 2 368 ? 114.677 105.825 59.708  1.00 216.20 ? 368 PRO B CD  1 
ATOM   6028  N N   . GLN B 2 369 ? 116.144 102.442 59.271  1.00 258.88 ? 369 GLN B N   1 
ATOM   6029  C CA  . GLN B 2 369 ? 117.049 101.303 59.163  1.00 326.41 ? 369 GLN B CA  1 
ATOM   6030  C C   . GLN B 2 369 ? 116.611 100.121 60.043  1.00 341.93 ? 369 GLN B C   1 
ATOM   6031  O O   . GLN B 2 369 ? 116.985 98.985  59.740  1.00 373.72 ? 369 GLN B O   1 
ATOM   6032  C CB  . GLN B 2 369 ? 118.474 101.733 59.519  1.00 373.95 ? 369 GLN B CB  1 
ATOM   6033  C CG  . GLN B 2 369 ? 119.070 102.738 58.541  1.00 364.70 ? 369 GLN B CG  1 
ATOM   6034  C CD  . GLN B 2 369 ? 120.507 103.092 58.848  1.00 394.60 ? 369 GLN B CD  1 
ATOM   6035  O OE1 . GLN B 2 369 ? 121.049 102.747 59.898  1.00 418.14 ? 369 GLN B OE1 1 
ATOM   6036  N NE2 . GLN B 2 369 ? 121.146 103.793 57.925  1.00 427.68 ? 369 GLN B NE2 1 
ATOM   6037  N N   . LEU B 2 370 ? 115.844 100.375 61.123  1.00 270.48 ? 370 LEU B N   1 
ATOM   6038  C CA  . LEU B 2 370 ? 115.469 99.359  62.107  1.00 247.98 ? 370 LEU B CA  1 
ATOM   6039  C C   . LEU B 2 370 ? 113.959 99.088  62.193  1.00 261.68 ? 370 LEU B C   1 
ATOM   6040  O O   . LEU B 2 370 ? 113.575 98.025  62.708  1.00 208.55 ? 370 LEU B O   1 
ATOM   6041  C CB  . LEU B 2 370 ? 115.972 99.848  63.467  1.00 237.74 ? 370 LEU B CB  1 
ATOM   6042  C CG  . LEU B 2 370 ? 117.486 99.991  63.626  1.00 235.40 ? 370 LEU B CG  1 
ATOM   6043  C CD1 . LEU B 2 370 ? 117.808 100.551 65.019  1.00 230.28 ? 370 LEU B CD1 1 
ATOM   6044  C CD2 . LEU B 2 370 ? 118.201 98.655  63.378  1.00 248.31 ? 370 LEU B CD2 1 
ATOM   6045  N N   . LEU B 2 371 ? 113.138 100.050 61.714  1.00 256.67 ? 371 LEU B N   1 
ATOM   6046  C CA  . LEU B 2 371 ? 111.679 100.015 61.674  1.00 239.59 ? 371 LEU B CA  1 
ATOM   6047  C C   . LEU B 2 371 ? 111.070 99.986  63.087  1.00 233.55 ? 371 LEU B C   1 
ATOM   6048  O O   . LEU B 2 371 ? 110.020 99.360  63.292  1.00 273.65 ? 371 LEU B O   1 
ATOM   6049  C CB  . LEU B 2 371 ? 111.211 98.831  60.808  1.00 329.74 ? 371 LEU B CB  1 
ATOM   6050  C CG  . LEU B 2 371 ? 111.869 98.669  59.430  1.00 428.54 ? 371 LEU B CG  1 
ATOM   6051  C CD1 . LEU B 2 371 ? 111.282 97.483  58.691  1.00 502.58 ? 371 LEU B CD1 1 
ATOM   6052  C CD2 . LEU B 2 371 ? 111.736 99.918  58.582  1.00 457.73 ? 371 LEU B CD2 1 
ATOM   6053  N N   . THR B 2 372 ? 111.714 100.683 64.050  1.00 219.69 ? 372 THR B N   1 
ATOM   6054  C CA  . THR B 2 372 ? 111.247 100.775 65.439  1.00 202.85 ? 372 THR B CA  1 
ATOM   6055  C C   . THR B 2 372 ? 110.779 102.187 65.757  1.00 137.20 ? 372 THR B C   1 
ATOM   6056  O O   . THR B 2 372 ? 111.366 103.136 65.257  1.00 157.55 ? 372 THR B O   1 
ATOM   6057  C CB  . THR B 2 372 ? 112.318 100.366 66.452  1.00 209.29 ? 372 THR B CB  1 
ATOM   6058  O OG1 . THR B 2 372 ? 113.459 101.192 66.204  1.00 166.04 ? 372 THR B OG1 1 
ATOM   6059  C CG2 . THR B 2 372 ? 112.629 98.881  66.359  1.00 207.70 ? 372 THR B CG2 1 
ATOM   6060  N N   . PRO B 2 373 ? 109.684 102.369 66.534  1.00 147.45 ? 373 PRO B N   1 
ATOM   6061  C CA  . PRO B 2 373 ? 109.041 103.678 66.670  1.00 187.46 ? 373 PRO B CA  1 
ATOM   6062  C C   . PRO B 2 373 ? 109.716 104.609 67.675  1.00 173.08 ? 373 PRO B C   1 
ATOM   6063  O O   . PRO B 2 373 ? 109.029 105.096 68.562  1.00 136.83 ? 373 PRO B O   1 
ATOM   6064  C CB  . PRO B 2 373 ? 107.615 103.265 67.093  1.00 216.42 ? 373 PRO B CB  1 
ATOM   6065  C CG  . PRO B 2 373 ? 107.831 102.051 67.967  1.00 195.04 ? 373 PRO B CG  1 
ATOM   6066  C CD  . PRO B 2 373 ? 108.964 101.323 67.281  1.00 160.98 ? 373 PRO B CD  1 
ATOM   6067  N N   . VAL B 2 374 ? 111.023 104.858 67.459  1.00 135.27 ? 374 VAL B N   1 
ATOM   6068  C CA  . VAL B 2 374 ? 111.958 105.415 68.430  1.00 137.17 ? 374 VAL B CA  1 
ATOM   6069  C C   . VAL B 2 374 ? 111.457 106.640 69.189  1.00 135.88 ? 374 VAL B C   1 
ATOM   6070  O O   . VAL B 2 374 ? 111.590 106.611 70.407  1.00 197.32 ? 374 VAL B O   1 
ATOM   6071  C CB  . VAL B 2 374 ? 113.284 105.704 67.738  1.00 158.27 ? 374 VAL B CB  1 
ATOM   6072  C CG1 . VAL B 2 374 ? 114.166 106.744 68.452  1.00 140.15 ? 374 VAL B CG1 1 
ATOM   6073  C CG2 . VAL B 2 374 ? 113.968 104.346 67.524  1.00 160.62 ? 374 VAL B CG2 1 
ATOM   6074  N N   . PRO B 2 375 ? 110.854 107.695 68.609  1.00 131.77 ? 375 PRO B N   1 
ATOM   6075  C CA  . PRO B 2 375 ? 110.377 108.825 69.425  1.00 159.27 ? 375 PRO B CA  1 
ATOM   6076  C C   . PRO B 2 375 ? 109.248 108.450 70.389  1.00 174.28 ? 375 PRO B C   1 
ATOM   6077  O O   . PRO B 2 375 ? 109.228 108.975 71.500  1.00 216.96 ? 375 PRO B O   1 
ATOM   6078  C CB  . PRO B 2 375 ? 109.867 109.840 68.415  1.00 213.38 ? 375 PRO B CB  1 
ATOM   6079  C CG  . PRO B 2 375 ? 110.501 109.367 67.113  1.00 263.96 ? 375 PRO B CG  1 
ATOM   6080  C CD  . PRO B 2 375 ? 110.543 107.858 67.195  1.00 182.72 ? 375 PRO B CD  1 
ATOM   6081  N N   . SER B 2 376 ? 108.346 107.535 69.987  1.00 171.41 ? 376 SER B N   1 
ATOM   6082  C CA  . SER B 2 376 ? 107.332 107.025 70.906  1.00 209.93 ? 376 SER B CA  1 
ATOM   6083  C C   . SER B 2 376 ? 107.929 106.213 72.077  1.00 180.91 ? 376 SER B C   1 
ATOM   6084  O O   . SER B 2 376 ? 107.530 106.394 73.226  1.00 133.72 ? 376 SER B O   1 
ATOM   6085  C CB  . SER B 2 376 ? 106.310 106.225 70.150  1.00 242.07 ? 376 SER B CB  1 
ATOM   6086  O OG  . SER B 2 376 ? 105.322 105.689 71.012  1.00 296.06 ? 376 SER B OG  1 
ATOM   6087  N N   . LEU B 2 377 ? 108.878 105.305 71.806  1.00 139.11 ? 377 LEU B N   1 
ATOM   6088  C CA  . LEU B 2 377 ? 109.545 104.578 72.870  1.00 135.65 ? 377 LEU B CA  1 
ATOM   6089  C C   . LEU B 2 377 ? 110.272 105.514 73.830  1.00 158.38 ? 377 LEU B C   1 
ATOM   6090  O O   . LEU B 2 377 ? 110.159 105.353 75.047  1.00 177.43 ? 377 LEU B O   1 
ATOM   6091  C CB  . LEU B 2 377 ? 110.525 103.557 72.281  1.00 124.61 ? 377 LEU B CB  1 
ATOM   6092  C CG  . LEU B 2 377 ? 109.873 102.219 71.957  1.00 135.96 ? 377 LEU B CG  1 
ATOM   6093  C CD1 . LEU B 2 377 ? 110.809 101.361 71.160  1.00 161.16 ? 377 LEU B CD1 1 
ATOM   6094  C CD2 . LEU B 2 377 ? 109.483 101.442 73.203  1.00 231.54 ? 377 LEU B CD2 1 
ATOM   6095  N N   . VAL B 2 378 ? 111.014 106.471 73.294  1.00 139.64 ? 378 VAL B N   1 
ATOM   6096  C CA  . VAL B 2 378 ? 111.724 107.405 74.146  1.00 161.96 ? 378 VAL B CA  1 
ATOM   6097  C C   . VAL B 2 378 ? 110.749 108.234 74.980  1.00 138.03 ? 378 VAL B C   1 
ATOM   6098  O O   . VAL B 2 378 ? 111.077 108.584 76.106  1.00 188.76 ? 378 VAL B O   1 
ATOM   6099  C CB  . VAL B 2 378 ? 112.692 108.231 73.291  1.00 215.47 ? 378 VAL B CB  1 
ATOM   6100  C CG1 . VAL B 2 378 ? 113.068 109.599 73.867  1.00 261.22 ? 378 VAL B CG1 1 
ATOM   6101  C CG2 . VAL B 2 378 ? 113.915 107.363 73.028  1.00 251.74 ? 378 VAL B CG2 1 
ATOM   6102  N N   . PHE B 2 379 ? 109.564 108.525 74.465  1.00 128.76 ? 379 PHE B N   1 
ATOM   6103  C CA  . PHE B 2 379 ? 108.600 109.276 75.238  1.00 155.26 ? 379 PHE B CA  1 
ATOM   6104  C C   . PHE B 2 379 ? 108.033 108.409 76.345  1.00 162.53 ? 379 PHE B C   1 
ATOM   6105  O O   . PHE B 2 379 ? 108.031 108.866 77.479  1.00 191.54 ? 379 PHE B O   1 
ATOM   6106  C CB  . PHE B 2 379 ? 107.444 109.781 74.372  1.00 214.03 ? 379 PHE B CB  1 
ATOM   6107  C CG  . PHE B 2 379 ? 106.391 110.532 75.145  1.00 171.70 ? 379 PHE B CG  1 
ATOM   6108  C CD1 . PHE B 2 379 ? 106.575 111.860 75.495  1.00 218.37 ? 379 PHE B CD1 1 
ATOM   6109  C CD2 . PHE B 2 379 ? 105.225 109.903 75.528  1.00 220.68 ? 379 PHE B CD2 1 
ATOM   6110  C CE1 . PHE B 2 379 ? 105.607 112.553 76.206  1.00 228.74 ? 379 PHE B CE1 1 
ATOM   6111  C CE2 . PHE B 2 379 ? 104.259 110.589 76.244  1.00 266.55 ? 379 PHE B CE2 1 
ATOM   6112  C CZ  . PHE B 2 379 ? 104.451 111.913 76.580  1.00 285.12 ? 379 PHE B CZ  1 
ATOM   6113  N N   . THR B 2 380 ? 107.539 107.196 76.032  1.00 182.47 ? 380 THR B N   1 
ATOM   6114  C CA  . THR B 2 380 ? 106.863 106.384 77.047  1.00 191.93 ? 380 THR B CA  1 
ATOM   6115  C C   . THR B 2 380 ? 107.843 105.999 78.145  1.00 163.51 ? 380 THR B C   1 
ATOM   6116  O O   . THR B 2 380 ? 107.422 105.940 79.313  1.00 157.02 ? 380 THR B O   1 
ATOM   6117  C CB  . THR B 2 380 ? 106.145 105.154 76.466  1.00 214.53 ? 380 THR B CB  1 
ATOM   6118  O OG1 . THR B 2 380 ? 105.284 104.646 77.498  1.00 254.36 ? 380 THR B OG1 1 
ATOM   6119  C CG2 . THR B 2 380 ? 107.072 104.075 75.942  1.00 141.65 ? 380 THR B CG2 1 
ATOM   6120  N N   . CYS B 2 381 ? 109.112 105.745 77.757  1.00 108.95 ? 381 CYS B N   1 
ATOM   6121  C CA  . CYS B 2 381 ? 110.175 105.600 78.728  1.00 141.46 ? 381 CYS B CA  1 
ATOM   6122  C C   . CYS B 2 381 ? 110.278 106.819 79.669  1.00 156.25 ? 381 CYS B C   1 
ATOM   6123  O O   . CYS B 2 381 ? 110.108 106.706 80.875  1.00 127.96 ? 381 CYS B O   1 
ATOM   6124  C CB  . CYS B 2 381 ? 111.507 105.360 78.038  1.00 149.05 ? 381 CYS B CB  1 
ATOM   6125  S SG  . CYS B 2 381 ? 112.914 105.215 79.201  1.00 173.80 ? 381 CYS B SG  1 
ATOM   6126  N N   . VAL B 2 382 ? 110.581 107.999 79.144  1.00 152.99 ? 382 VAL B N   1 
ATOM   6127  C CA  . VAL B 2 382 ? 110.773 109.167 79.986  1.00 150.20 ? 382 VAL B CA  1 
ATOM   6128  C C   . VAL B 2 382 ? 109.526 109.421 80.828  1.00 151.07 ? 382 VAL B C   1 
ATOM   6129  O O   . VAL B 2 382 ? 109.652 109.789 81.982  1.00 227.73 ? 382 VAL B O   1 
ATOM   6130  C CB  . VAL B 2 382 ? 111.176 110.379 79.126  1.00 252.17 ? 382 VAL B CB  1 
ATOM   6131  C CG1 . VAL B 2 382 ? 110.810 111.742 79.714  1.00 332.35 ? 382 VAL B CG1 1 
ATOM   6132  C CG2 . VAL B 2 382 ? 112.668 110.295 78.840  1.00 277.89 ? 382 VAL B CG2 1 
ATOM   6133  N N   . MET B 2 383 ? 108.342 109.234 80.265  1.00 154.99 ? 383 MET B N   1 
ATOM   6134  C CA  . MET B 2 383 ? 107.105 109.463 80.983  1.00 176.96 ? 383 MET B CA  1 
ATOM   6135  C C   . MET B 2 383 ? 106.977 108.477 82.155  1.00 185.92 ? 383 MET B C   1 
ATOM   6136  O O   . MET B 2 383 ? 106.354 108.810 83.152  1.00 187.40 ? 383 MET B O   1 
ATOM   6137  C CB  . MET B 2 383 ? 105.942 109.307 79.994  1.00 202.01 ? 383 MET B CB  1 
ATOM   6138  C CG  . MET B 2 383 ? 104.657 109.921 80.439  1.00 242.85 ? 383 MET B CG  1 
ATOM   6139  S SD  . MET B 2 383 ? 104.732 111.725 80.402  1.00 332.51 ? 383 MET B SD  1 
ATOM   6140  C CE  . MET B 2 383 ? 103.137 112.122 81.116  1.00 287.62 ? 383 MET B CE  1 
ATOM   6141  N N   . THR B 2 384 ? 107.556 107.265 82.044  1.00 154.46 ? 384 THR B N   1 
ATOM   6142  C CA  . THR B 2 384 ? 107.566 106.280 83.121  1.00 154.12 ? 384 THR B CA  1 
ATOM   6143  C C   . THR B 2 384 ? 108.483 106.716 84.247  1.00 138.73 ? 384 THR B C   1 
ATOM   6144  O O   . THR B 2 384 ? 108.143 106.579 85.412  1.00 159.15 ? 384 THR B O   1 
ATOM   6145  C CB  . THR B 2 384 ? 108.036 104.888 82.658  1.00 158.14 ? 384 THR B CB  1 
ATOM   6146  O OG1 . THR B 2 384 ? 107.074 104.503 81.670  1.00 208.24 ? 384 THR B OG1 1 
ATOM   6147  C CG2 . THR B 2 384 ? 108.149 103.823 83.742  1.00 138.23 ? 384 THR B CG2 1 
ATOM   6148  N N   . LEU B 2 385 ? 109.665 107.211 83.901  1.00 130.63 ? 385 LEU B N   1 
ATOM   6149  C CA  . LEU B 2 385 ? 110.639 107.531 84.925  1.00 141.58 ? 385 LEU B CA  1 
ATOM   6150  C C   . LEU B 2 385 ? 110.198 108.716 85.780  1.00 142.74 ? 385 LEU B C   1 
ATOM   6151  O O   . LEU B 2 385 ? 110.661 108.806 86.904  1.00 158.41 ? 385 LEU B O   1 
ATOM   6152  C CB  . LEU B 2 385 ? 111.972 107.776 84.229  1.00 151.05 ? 385 LEU B CB  1 
ATOM   6153  C CG  . LEU B 2 385 ? 112.526 106.554 83.495  1.00 174.65 ? 385 LEU B CG  1 
ATOM   6154  C CD1 . LEU B 2 385 ? 113.860 106.892 82.894  1.00 205.13 ? 385 LEU B CD1 1 
ATOM   6155  C CD2 . LEU B 2 385 ? 112.645 105.342 84.418  1.00 161.37 ? 385 LEU B CD2 1 
ATOM   6156  N N   . LEU B 2 386 ? 109.310 109.588 85.285  1.00 150.52 ? 386 LEU B N   1 
ATOM   6157  C CA  . LEU B 2 386 ? 108.762 110.666 86.102  1.00 206.01 ? 386 LEU B CA  1 
ATOM   6158  C C   . LEU B 2 386 ? 108.027 110.153 87.353  1.00 186.56 ? 386 LEU B C   1 
ATOM   6159  O O   . LEU B 2 386 ? 107.933 110.897 88.347  1.00 243.46 ? 386 LEU B O   1 
ATOM   6160  C CB  . LEU B 2 386 ? 107.829 111.541 85.255  1.00 250.61 ? 386 LEU B CB  1 
ATOM   6161  C CG  . LEU B 2 386 ? 108.471 112.284 84.082  1.00 325.57 ? 386 LEU B CG  1 
ATOM   6162  C CD1 . LEU B 2 386 ? 107.428 113.145 83.388  1.00 364.48 ? 386 LEU B CD1 1 
ATOM   6163  C CD2 . LEU B 2 386 ? 109.668 113.125 84.517  1.00 402.35 ? 386 LEU B CD2 1 
ATOM   6164  N N   . TYR B 2 387 ? 107.531 108.908 87.318  1.00 140.11 ? 387 TYR B N   1 
ATOM   6165  C CA  . TYR B 2 387 ? 106.872 108.322 88.476  1.00 179.95 ? 387 TYR B CA  1 
ATOM   6166  C C   . TYR B 2 387 ? 107.863 107.986 89.603  1.00 146.58 ? 387 TYR B C   1 
ATOM   6167  O O   . TYR B 2 387 ? 107.419 107.735 90.730  1.00 134.22 ? 387 TYR B O   1 
ATOM   6168  C CB  . TYR B 2 387 ? 105.976 107.161 87.992  1.00 205.90 ? 387 TYR B CB  1 
ATOM   6169  C CG  . TYR B 2 387 ? 104.666 107.741 87.497  1.00 177.24 ? 387 TYR B CG  1 
ATOM   6170  C CD1 . TYR B 2 387 ? 104.534 108.277 86.230  1.00 190.20 ? 387 TYR B CD1 1 
ATOM   6171  C CD2 . TYR B 2 387 ? 103.575 107.798 88.345  1.00 170.08 ? 387 TYR B CD2 1 
ATOM   6172  C CE1 . TYR B 2 387 ? 103.337 108.839 85.818  1.00 283.72 ? 387 TYR B CE1 1 
ATOM   6173  C CE2 . TYR B 2 387 ? 102.375 108.356 87.949  1.00 204.48 ? 387 TYR B CE2 1 
ATOM   6174  C CZ  . TYR B 2 387 ? 102.255 108.875 86.679  1.00 268.21 ? 387 TYR B CZ  1 
ATOM   6175  O OH  . TYR B 2 387 ? 101.064 109.415 86.322  1.00 284.13 ? 387 TYR B OH  1 
ATOM   6176  N N   . ALA B 2 388 ? 109.176 107.987 89.344  1.00 119.17 ? 388 ALA B N   1 
ATOM   6177  C CA  . ALA B 2 388 ? 110.143 107.913 90.436  1.00 212.86 ? 388 ALA B CA  1 
ATOM   6178  C C   . ALA B 2 388 ? 109.975 109.002 91.511  1.00 242.93 ? 388 ALA B C   1 
ATOM   6179  O O   . ALA B 2 388 ? 110.364 108.802 92.667  1.00 233.99 ? 388 ALA B O   1 
ATOM   6180  C CB  . ALA B 2 388 ? 111.539 107.909 89.851  1.00 248.92 ? 388 ALA B CB  1 
ATOM   6181  N N   . PHE B 2 389 ? 109.410 110.171 91.151  1.00 266.15 ? 389 PHE B N   1 
ATOM   6182  C CA  . PHE B 2 389 ? 109.221 111.273 92.093  1.00 278.75 ? 389 PHE B CA  1 
ATOM   6183  C C   . PHE B 2 389 ? 107.898 111.115 92.849  1.00 278.29 ? 389 PHE B C   1 
ATOM   6184  O O   . PHE B 2 389 ? 107.325 112.113 93.284  1.00 360.94 ? 389 PHE B O   1 
ATOM   6185  C CB  . PHE B 2 389 ? 109.357 112.621 91.358  1.00 273.57 ? 389 PHE B CB  1 
ATOM   6186  C CG  . PHE B 2 389 ? 110.627 112.747 90.542  1.00 285.60 ? 389 PHE B CG  1 
ATOM   6187  C CD1 . PHE B 2 389 ? 111.871 112.421 91.093  1.00 226.09 ? 389 PHE B CD1 1 
ATOM   6188  C CD2 . PHE B 2 389 ? 110.596 113.172 89.218  1.00 393.07 ? 389 PHE B CD2 1 
ATOM   6189  C CE1 . PHE B 2 389 ? 113.038 112.508 90.351  1.00 222.15 ? 389 PHE B CE1 1 
ATOM   6190  C CE2 . PHE B 2 389 ? 111.771 113.269 88.478  1.00 388.93 ? 389 PHE B CE2 1 
ATOM   6191  C CZ  . PHE B 2 389 ? 112.988 112.939 89.043  1.00 306.81 ? 389 PHE B CZ  1 
ATOM   6192  N N   . SER B 2 390 ? 107.417 109.870 93.014  1.00 198.01 ? 390 SER B N   1 
ATOM   6193  C CA  . SER B 2 390 ? 106.225 109.567 93.787  1.00 244.55 ? 390 SER B CA  1 
ATOM   6194  C C   . SER B 2 390 ? 106.641 108.752 95.009  1.00 298.75 ? 390 SER B C   1 
ATOM   6195  O O   . SER B 2 390 ? 107.457 107.838 94.887  1.00 346.41 ? 390 SER B O   1 
ATOM   6196  C CB  . SER B 2 390 ? 105.223 108.837 92.923  1.00 259.08 ? 390 SER B CB  1 
ATOM   6197  O OG  . SER B 2 390 ? 103.988 108.618 93.598  1.00 274.05 ? 390 SER B OG  1 
ATOM   6198  N N   . LYS B 2 391 ? 106.076 109.073 96.185  1.00 305.21 ? 391 LYS B N   1 
ATOM   6199  C CA  . LYS B 2 391 ? 106.386 108.364 97.421  1.00 327.92 ? 391 LYS B CA  1 
ATOM   6200  C C   . LYS B 2 391 ? 105.548 107.080 97.510  1.00 329.87 ? 391 LYS B C   1 
ATOM   6201  O O   . LYS B 2 391 ? 106.097 105.990 97.364  1.00 271.46 ? 391 LYS B O   1 
ATOM   6202  C CB  . LYS B 2 391 ? 106.197 109.305 98.619  1.00 401.52 ? 391 LYS B CB  1 
ATOM   6203  C CG  . LYS B 2 391 ? 106.679 108.760 99.958  1.00 483.15 ? 391 LYS B CG  1 
ATOM   6204  C CD  . LYS B 2 391 ? 108.195 108.671 100.070 1.00 531.75 ? 391 LYS B CD  1 
ATOM   6205  C CE  . LYS B 2 391 ? 108.692 108.172 101.414 1.00 567.65 ? 391 LYS B CE  1 
ATOM   6206  N NZ  . LYS B 2 391 ? 108.769 106.691 101.475 1.00 590.73 ? 391 LYS B NZ  1 
ATOM   6207  N N   . ASP B 2 392 ? 104.229 107.202 97.745  1.00 394.66 ? 392 ASP B N   1 
ATOM   6208  C CA  . ASP B 2 392 ? 103.347 106.052 97.933  1.00 426.56 ? 392 ASP B CA  1 
ATOM   6209  C C   . ASP B 2 392 ? 102.702 105.700 96.591  1.00 343.03 ? 392 ASP B C   1 
ATOM   6210  O O   . ASP B 2 392 ? 101.493 105.858 96.405  1.00 322.17 ? 392 ASP B O   1 
ATOM   6211  C CB  . ASP B 2 392 ? 102.326 106.321 99.048  1.00 531.36 ? 392 ASP B CB  1 
ATOM   6212  C CG  . ASP B 2 392 ? 101.535 105.108 99.522  1.00 599.24 ? 392 ASP B CG  1 
ATOM   6213  O OD1 . ASP B 2 392 ? 101.814 103.982 99.055  1.00 598.82 ? 392 ASP B OD1 1 
ATOM   6214  O OD2 . ASP B 2 392 ? 100.635 105.299 100.366 1.00 660.43 ? 392 ASP B OD2 1 
ATOM   6215  N N   . ILE B 2 393 ? 103.532 105.211 95.659  1.00 310.84 ? 393 ILE B N   1 
ATOM   6216  C CA  . ILE B 2 393 ? 103.111 104.967 94.277  1.00 339.40 ? 393 ILE B CA  1 
ATOM   6217  C C   . ILE B 2 393 ? 102.046 103.861 94.202  1.00 323.67 ? 393 ILE B C   1 
ATOM   6218  O O   . ILE B 2 393 ? 101.176 103.907 93.326  1.00 283.41 ? 393 ILE B O   1 
ATOM   6219  C CB  . ILE B 2 393 ? 104.325 104.685 93.349  1.00 351.74 ? 393 ILE B CB  1 
ATOM   6220  C CG1 . ILE B 2 393 ? 103.928 104.442 91.885  1.00 321.72 ? 393 ILE B CG1 1 
ATOM   6221  C CG2 . ILE B 2 393 ? 105.191 103.537 93.855  1.00 364.00 ? 393 ILE B CG2 1 
ATOM   6222  C CD1 . ILE B 2 393 ? 103.190 105.595 91.255  1.00 359.22 ? 393 ILE B CD1 1 
ATOM   6223  N N   . PHE B 2 394 ? 102.092 102.875 95.112  1.00 271.22 ? 394 PHE B N   1 
ATOM   6224  C CA  . PHE B 2 394 ? 101.140 101.764 95.076  1.00 236.67 ? 394 PHE B CA  1 
ATOM   6225  C C   . PHE B 2 394 ? 99.694  102.197 95.361  1.00 226.83 ? 394 PHE B C   1 
ATOM   6226  O O   . PHE B 2 394 ? 98.779  101.443 95.025  1.00 195.30 ? 394 PHE B O   1 
ATOM   6227  C CB  . PHE B 2 394 ? 101.609 100.640 95.997  1.00 208.09 ? 394 PHE B CB  1 
ATOM   6228  C CG  . PHE B 2 394 ? 102.811 99.937  95.428  1.00 231.07 ? 394 PHE B CG  1 
ATOM   6229  C CD1 . PHE B 2 394 ? 104.093 100.434 95.629  1.00 264.85 ? 394 PHE B CD1 1 
ATOM   6230  C CD2 . PHE B 2 394 ? 102.660 98.782  94.667  1.00 241.06 ? 394 PHE B CD2 1 
ATOM   6231  C CE1 . PHE B 2 394 ? 105.198 99.780  95.092  1.00 328.90 ? 394 PHE B CE1 1 
ATOM   6232  C CE2 . PHE B 2 394 ? 103.768 98.127  94.128  1.00 273.25 ? 394 PHE B CE2 1 
ATOM   6233  C CZ  . PHE B 2 394 ? 105.038 98.628  94.341  1.00 295.87 ? 394 PHE B CZ  1 
ATOM   6234  N N   . SER B 2 395 ? 99.502  103.396 95.950  1.00 293.43 ? 395 SER B N   1 
ATOM   6235  C CA  . SER B 2 395 ? 98.220  104.095 96.004  1.00 335.08 ? 395 SER B CA  1 
ATOM   6236  C C   . SER B 2 395 ? 97.538  104.191 94.636  1.00 348.32 ? 395 SER B C   1 
ATOM   6237  O O   . SER B 2 395 ? 96.319  104.060 94.567  1.00 335.24 ? 395 SER B O   1 
ATOM   6238  C CB  . SER B 2 395 ? 98.380  105.483 96.599  1.00 344.40 ? 395 SER B CB  1 
ATOM   6239  O OG  . SER B 2 395 ? 97.118  106.101 96.815  1.00 374.29 ? 395 SER B OG  1 
ATOM   6240  N N   . VAL B 2 396 ? 98.310  104.408 93.555  1.00 329.42 ? 396 VAL B N   1 
ATOM   6241  C CA  . VAL B 2 396 ? 97.756  104.707 92.237  1.00 283.63 ? 396 VAL B CA  1 
ATOM   6242  C C   . VAL B 2 396 ? 97.026  103.487 91.655  1.00 211.15 ? 396 VAL B C   1 
ATOM   6243  O O   . VAL B 2 396 ? 96.286  103.653 90.691  1.00 168.15 ? 396 VAL B O   1 
ATOM   6244  C CB  . VAL B 2 396 ? 98.866  105.256 91.306  1.00 317.74 ? 396 VAL B CB  1 
ATOM   6245  C CG1 . VAL B 2 396 ? 98.412  105.480 89.858  1.00 368.55 ? 396 VAL B CG1 1 
ATOM   6246  C CG2 . VAL B 2 396 ? 99.474  106.537 91.883  1.00 321.38 ? 396 VAL B CG2 1 
ATOM   6247  N N   . ILE B 2 397 ? 97.205  102.278 92.229  1.00 228.80 ? 397 ILE B N   1 
ATOM   6248  C CA  . ILE B 2 397 ? 96.466  101.089 91.809  1.00 261.12 ? 397 ILE B CA  1 
ATOM   6249  C C   . ILE B 2 397 ? 94.947  101.287 91.973  1.00 265.41 ? 397 ILE B C   1 
ATOM   6250  O O   . ILE B 2 397 ? 94.202  100.703 91.189  1.00 331.67 ? 397 ILE B O   1 
ATOM   6251  C CB  . ILE B 2 397 ? 97.005  99.812  92.500  1.00 263.49 ? 397 ILE B CB  1 
ATOM   6252  C CG1 . ILE B 2 397 ? 98.436  99.515  92.048  1.00 204.79 ? 397 ILE B CG1 1 
ATOM   6253  C CG2 . ILE B 2 397 ? 96.119  98.580  92.259  1.00 267.27 ? 397 ILE B CG2 1 
ATOM   6254  C CD1 . ILE B 2 397 ? 99.158  98.495  92.911  1.00 234.22 ? 397 ILE B CD1 1 
ATOM   6255  N N   . ASN B 2 398 ? 94.455  102.097 92.926  1.00 259.92 ? 398 ASN B N   1 
ATOM   6256  C CA  . ASN B 2 398 ? 93.016  102.384 92.963  1.00 337.93 ? 398 ASN B CA  1 
ATOM   6257  C C   . ASN B 2 398 ? 92.590  103.190 91.712  1.00 370.27 ? 398 ASN B C   1 
ATOM   6258  O O   . ASN B 2 398 ? 91.641  102.775 91.037  1.00 244.09 ? 398 ASN B O   1 
ATOM   6259  C CB  . ASN B 2 398 ? 92.559  102.934 94.331  1.00 368.00 ? 398 ASN B CB  1 
ATOM   6260  C CG  . ASN B 2 398 ? 93.155  104.249 94.798  1.00 389.60 ? 398 ASN B CG  1 
ATOM   6261  O OD1 . ASN B 2 398 ? 93.532  105.109 94.007  1.00 454.01 ? 398 ASN B OD1 1 
ATOM   6262  N ND2 . ASN B 2 398 ? 93.228  104.426 96.108  1.00 377.95 ? 398 ASN B ND2 1 
ATOM   6263  N N   . PHE B 2 399 ? 93.281  104.303 91.380  1.00 389.27 ? 399 PHE B N   1 
ATOM   6264  C CA  . PHE B 2 399 ? 93.012  105.110 90.184  1.00 328.20 ? 399 PHE B CA  1 
ATOM   6265  C C   . PHE B 2 399 ? 93.140  104.274 88.904  1.00 286.57 ? 399 PHE B C   1 
ATOM   6266  O O   . PHE B 2 399 ? 92.267  104.372 88.044  1.00 198.90 ? 399 PHE B O   1 
ATOM   6267  C CB  . PHE B 2 399 ? 93.926  106.344 90.142  1.00 306.46 ? 399 PHE B CB  1 
ATOM   6268  C CG  . PHE B 2 399 ? 93.589  107.390 91.175  1.00 399.68 ? 399 PHE B CG  1 
ATOM   6269  C CD1 . PHE B 2 399 ? 92.409  108.117 91.074  1.00 450.06 ? 399 PHE B CD1 1 
ATOM   6270  C CD2 . PHE B 2 399 ? 94.434  107.649 92.252  1.00 420.81 ? 399 PHE B CD2 1 
ATOM   6271  C CE1 . PHE B 2 399 ? 92.082  109.083 92.021  1.00 482.82 ? 399 PHE B CE1 1 
ATOM   6272  C CE2 . PHE B 2 399 ? 94.107  108.615 93.198  1.00 421.00 ? 399 PHE B CE2 1 
ATOM   6273  C CZ  . PHE B 2 399 ? 92.930  109.331 93.083  1.00 442.52 ? 399 PHE B CZ  1 
ATOM   6274  N N   . PHE B 2 400 ? 94.209  103.456 88.794  1.00 325.34 ? 400 PHE B N   1 
ATOM   6275  C CA  . PHE B 2 400 ? 94.411  102.500 87.702  1.00 312.08 ? 400 PHE B CA  1 
ATOM   6276  C C   . PHE B 2 400 ? 93.179  101.602 87.535  1.00 278.56 ? 400 PHE B C   1 
ATOM   6277  O O   . PHE B 2 400 ? 92.688  101.465 86.420  1.00 253.75 ? 400 PHE B O   1 
ATOM   6278  C CB  . PHE B 2 400 ? 95.705  101.690 87.917  1.00 290.17 ? 400 PHE B CB  1 
ATOM   6279  C CG  . PHE B 2 400 ? 95.986  100.558 86.950  1.00 248.30 ? 400 PHE B CG  1 
ATOM   6280  C CD1 . PHE B 2 400 ? 95.346  99.318  87.062  1.00 287.48 ? 400 PHE B CD1 1 
ATOM   6281  C CD2 . PHE B 2 400 ? 96.904  100.723 85.922  1.00 239.69 ? 400 PHE B CD2 1 
ATOM   6282  C CE1 . PHE B 2 400 ? 95.601  98.284  86.166  1.00 277.72 ? 400 PHE B CE1 1 
ATOM   6283  C CE2 . PHE B 2 400 ? 97.160  99.685  85.026  1.00 299.05 ? 400 PHE B CE2 1 
ATOM   6284  C CZ  . PHE B 2 400 ? 96.514  98.466  85.148  1.00 256.03 ? 400 PHE B CZ  1 
ATOM   6285  N N   . SER B 2 401 ? 92.688  101.001 88.631  1.00 279.21 ? 401 SER B N   1 
ATOM   6286  C CA  . SER B 2 401 ? 91.577  100.058 88.580  1.00 277.99 ? 401 SER B CA  1 
ATOM   6287  C C   . SER B 2 401 ? 90.281  100.762 88.162  1.00 289.98 ? 401 SER B C   1 
ATOM   6288  O O   . SER B 2 401 ? 89.502  100.213 87.385  1.00 259.27 ? 401 SER B O   1 
ATOM   6289  C CB  . SER B 2 401 ? 91.428  99.314  89.899  1.00 309.47 ? 401 SER B CB  1 
ATOM   6290  O OG  . SER B 2 401 ? 91.015  100.175 90.952  1.00 303.38 ? 401 SER B OG  1 
ATOM   6291  N N   . PHE B 2 402 ? 90.040  101.981 88.664  1.00 277.86 ? 402 PHE B N   1 
ATOM   6292  C CA  . PHE B 2 402 ? 88.853  102.738 88.292  1.00 292.94 ? 402 PHE B CA  1 
ATOM   6293  C C   . PHE B 2 402 ? 88.887  103.104 86.805  1.00 268.00 ? 402 PHE B C   1 
ATOM   6294  O O   . PHE B 2 402 ? 87.940  102.773 86.098  1.00 174.10 ? 402 PHE B O   1 
ATOM   6295  C CB  . PHE B 2 402 ? 88.713  103.981 89.175  1.00 332.69 ? 402 PHE B CB  1 
ATOM   6296  C CG  . PHE B 2 402 ? 87.592  104.899 88.767  1.00 375.28 ? 402 PHE B CG  1 
ATOM   6297  C CD1 . PHE B 2 402 ? 86.272  104.622 89.110  1.00 426.96 ? 402 PHE B CD1 1 
ATOM   6298  C CD2 . PHE B 2 402 ? 87.862  106.039 88.024  1.00 325.84 ? 402 PHE B CD2 1 
ATOM   6299  C CE1 . PHE B 2 402 ? 85.246  105.476 88.724  1.00 440.14 ? 402 PHE B CE1 1 
ATOM   6300  C CE2 . PHE B 2 402 ? 86.837  106.894 87.640  1.00 348.27 ? 402 PHE B CE2 1 
ATOM   6301  C CZ  . PHE B 2 402 ? 85.530  106.611 87.989  1.00 430.32 ? 402 PHE B CZ  1 
ATOM   6302  N N   . PHE B 2 403 ? 89.970  103.781 86.373  1.00 296.66 ? 403 PHE B N   1 
ATOM   6303  C CA  . PHE B 2 403 ? 90.108  104.337 85.031  1.00 278.36 ? 403 PHE B CA  1 
ATOM   6304  C C   . PHE B 2 403 ? 90.120  103.251 83.951  1.00 193.75 ? 403 PHE B C   1 
ATOM   6305  O O   . PHE B 2 403 ? 89.511  103.434 82.906  1.00 194.27 ? 403 PHE B O   1 
ATOM   6306  C CB  . PHE B 2 403 ? 91.396  105.161 84.906  1.00 309.23 ? 403 PHE B CB  1 
ATOM   6307  C CG  . PHE B 2 403 ? 91.507  106.478 85.645  1.00 302.55 ? 403 PHE B CG  1 
ATOM   6308  C CD1 . PHE B 2 403 ? 90.449  107.374 85.704  1.00 325.82 ? 403 PHE B CD1 1 
ATOM   6309  C CD2 . PHE B 2 403 ? 92.702  106.836 86.269  1.00 284.39 ? 403 PHE B CD2 1 
ATOM   6310  C CE1 . PHE B 2 403 ? 90.582  108.581 86.382  1.00 369.39 ? 403 PHE B CE1 1 
ATOM   6311  C CE2 . PHE B 2 403 ? 92.836  108.042 86.942  1.00 266.26 ? 403 PHE B CE2 1 
ATOM   6312  C CZ  . PHE B 2 403 ? 91.774  108.915 86.997  1.00 353.09 ? 403 PHE B CZ  1 
ATOM   6313  N N   . ASN B 2 404 ? 90.803  102.133 84.206  1.00 159.94 ? 404 ASN B N   1 
ATOM   6314  C CA  . ASN B 2 404 ? 90.937  101.066 83.229  1.00 179.22 ? 404 ASN B CA  1 
ATOM   6315  C C   . ASN B 2 404 ? 89.548  100.461 82.939  1.00 215.10 ? 404 ASN B C   1 
ATOM   6316  O O   . ASN B 2 404 ? 89.149  100.478 81.774  1.00 237.75 ? 404 ASN B O   1 
ATOM   6317  C CB  . ASN B 2 404 ? 92.034  100.110 83.713  1.00 212.49 ? 404 ASN B CB  1 
ATOM   6318  C CG  . ASN B 2 404 ? 92.423  98.969  82.790  1.00 249.14 ? 404 ASN B CG  1 
ATOM   6319  O OD1 . ASN B 2 404 ? 91.753  98.696  81.796  1.00 323.50 ? 404 ASN B OD1 1 
ATOM   6320  N ND2 . ASN B 2 404 ? 93.517  98.289  83.123  1.00 231.55 ? 404 ASN B ND2 1 
ATOM   6321  N N   . TRP B 2 405 ? 88.791  99.944  83.935  1.00 187.82 ? 405 TRP B N   1 
ATOM   6322  C CA  . TRP B 2 405 ? 87.588  99.168  83.597  1.00 199.24 ? 405 TRP B CA  1 
ATOM   6323  C C   . TRP B 2 405 ? 86.457  100.078 83.113  1.00 228.88 ? 405 TRP B C   1 
ATOM   6324  O O   . TRP B 2 405 ? 85.578  99.564  82.428  1.00 276.81 ? 405 TRP B O   1 
ATOM   6325  C CB  . TRP B 2 405 ? 87.072  98.222  84.703  1.00 221.98 ? 405 TRP B CB  1 
ATOM   6326  C CG  . TRP B 2 405 ? 88.191  97.505  85.390  1.00 246.73 ? 405 TRP B CG  1 
ATOM   6327  C CD1 . TRP B 2 405 ? 88.458  97.490  86.724  1.00 315.65 ? 405 TRP B CD1 1 
ATOM   6328  C CD2 . TRP B 2 405 ? 89.234  96.745  84.755  1.00 239.90 ? 405 TRP B CD2 1 
ATOM   6329  N NE1 . TRP B 2 405 ? 89.589  96.757  86.970  1.00 312.02 ? 405 TRP B NE1 1 
ATOM   6330  C CE2 . TRP B 2 405 ? 90.090  96.292  85.784  1.00 291.12 ? 405 TRP B CE2 1 
ATOM   6331  C CE3 . TRP B 2 405 ? 89.530  96.403  83.432  1.00 208.33 ? 405 TRP B CE3 1 
ATOM   6332  C CZ2 . TRP B 2 405 ? 91.218  95.517  85.523  1.00 318.75 ? 405 TRP B CZ2 1 
ATOM   6333  C CZ3 . TRP B 2 405 ? 90.652  95.649  83.175  1.00 297.34 ? 405 TRP B CZ3 1 
ATOM   6334  C CH2 . TRP B 2 405 ? 91.487  95.215  84.206  1.00 347.71 ? 405 TRP B CH2 1 
ATOM   6335  N N   . LEU B 2 406 ? 86.473  101.388 83.434  1.00 186.48 ? 406 LEU B N   1 
ATOM   6336  C CA  . LEU B 2 406 ? 85.579  102.354 82.797  1.00 216.30 ? 406 LEU B CA  1 
ATOM   6337  C C   . LEU B 2 406 ? 85.856  102.446 81.291  1.00 243.59 ? 406 LEU B C   1 
ATOM   6338  O O   . LEU B 2 406 ? 84.910  102.481 80.499  1.00 196.27 ? 406 LEU B O   1 
ATOM   6339  C CB  . LEU B 2 406 ? 85.724  103.721 83.484  1.00 231.25 ? 406 LEU B CB  1 
ATOM   6340  C CG  . LEU B 2 406 ? 85.006  104.906 82.832  1.00 305.07 ? 406 LEU B CG  1 
ATOM   6341  C CD1 . LEU B 2 406 ? 83.493  104.734 82.888  1.00 347.55 ? 406 LEU B CD1 1 
ATOM   6342  C CD2 . LEU B 2 406 ? 85.427  106.209 83.494  1.00 308.29 ? 406 LEU B CD2 1 
ATOM   6343  N N   . CYS B 2 407 ? 87.133  102.492 80.889  1.00 252.77 ? 407 CYS B N   1 
ATOM   6344  C CA  . CYS B 2 407 ? 87.466  102.518 79.473  1.00 237.93 ? 407 CYS B CA  1 
ATOM   6345  C C   . CYS B 2 407 ? 87.063  101.200 78.804  1.00 193.91 ? 407 CYS B C   1 
ATOM   6346  O O   . CYS B 2 407 ? 86.482  101.236 77.722  1.00 271.24 ? 407 CYS B O   1 
ATOM   6347  C CB  . CYS B 2 407 ? 88.932  102.881 79.280  1.00 271.84 ? 407 CYS B CB  1 
ATOM   6348  S SG  . CYS B 2 407 ? 89.328  104.539 79.909  1.00 300.50 ? 407 CYS B SG  1 
ATOM   6349  N N   . VAL B 2 408 ? 87.324  100.045 79.426  1.00 147.70 ? 408 VAL B N   1 
ATOM   6350  C CA  . VAL B 2 408 ? 86.857  98.778  78.863  1.00 193.78 ? 408 VAL B CA  1 
ATOM   6351  C C   . VAL B 2 408 ? 85.319  98.729  78.796  1.00 208.04 ? 408 VAL B C   1 
ATOM   6352  O O   . VAL B 2 408 ? 84.768  98.245  77.806  1.00 205.42 ? 408 VAL B O   1 
ATOM   6353  C CB  . VAL B 2 408 ? 87.446  97.561  79.599  1.00 250.35 ? 408 VAL B CB  1 
ATOM   6354  C CG1 . VAL B 2 408 ? 87.018  96.241  78.969  1.00 248.55 ? 408 VAL B CG1 1 
ATOM   6355  C CG2 . VAL B 2 408 ? 88.966  97.627  79.652  1.00 283.66 ? 408 VAL B CG2 1 
ATOM   6356  N N   . ALA B 2 409 ? 84.621  99.238  79.817  1.00 230.38 ? 409 ALA B N   1 
ATOM   6357  C CA  . ALA B 2 409 ? 83.168  99.335  79.775  1.00 268.89 ? 409 ALA B CA  1 
ATOM   6358  C C   . ALA B 2 409 ? 82.696  100.094 78.533  1.00 261.56 ? 409 ALA B C   1 
ATOM   6359  O O   . ALA B 2 409 ? 81.835  99.595  77.806  1.00 266.16 ? 409 ALA B O   1 
ATOM   6360  C CB  . ALA B 2 409 ? 82.645  100.020 81.015  1.00 334.46 ? 409 ALA B CB  1 
ATOM   6361  N N   . LEU B 2 410 ? 83.255  101.298 78.310  1.00 199.00 ? 410 LEU B N   1 
ATOM   6362  C CA  . LEU B 2 410 ? 82.886  102.127 77.170  1.00 209.22 ? 410 LEU B CA  1 
ATOM   6363  C C   . LEU B 2 410 ? 83.169  101.397 75.858  1.00 208.73 ? 410 LEU B C   1 
ATOM   6364  O O   . LEU B 2 410 ? 82.361  101.484 74.937  1.00 235.01 ? 410 LEU B O   1 
ATOM   6365  C CB  . LEU B 2 410 ? 83.647  103.451 77.231  1.00 222.55 ? 410 LEU B CB  1 
ATOM   6366  C CG  . LEU B 2 410 ? 83.246  104.405 78.353  1.00 313.25 ? 410 LEU B CG  1 
ATOM   6367  C CD1 . LEU B 2 410 ? 84.266  105.530 78.477  1.00 397.66 ? 410 LEU B CD1 1 
ATOM   6368  C CD2 . LEU B 2 410 ? 81.852  104.976 78.127  1.00 358.07 ? 410 LEU B CD2 1 
ATOM   6369  N N   . ALA B 2 411 ? 84.296  100.680 75.777  1.00 195.66 ? 411 ALA B N   1 
ATOM   6370  C CA  . ALA B 2 411 ? 84.639  99.923  74.584  1.00 204.74 ? 411 ALA B CA  1 
ATOM   6371  C C   . ALA B 2 411 ? 83.600  98.842  74.282  1.00 197.90 ? 411 ALA B C   1 
ATOM   6372  O O   . ALA B 2 411 ? 83.211  98.687  73.119  1.00 256.11 ? 411 ALA B O   1 
ATOM   6373  C CB  . ALA B 2 411 ? 86.008  99.319  74.739  1.00 259.21 ? 411 ALA B CB  1 
ATOM   6374  N N   . ILE B 2 412 ? 83.144  98.101  75.306  1.00 169.92 ? 412 ILE B N   1 
ATOM   6375  C CA  . ILE B 2 412 ? 82.205  97.010  75.060  1.00 231.37 ? 412 ILE B CA  1 
ATOM   6376  C C   . ILE B 2 412 ? 80.767  97.527  74.891  1.00 240.94 ? 412 ILE B C   1 
ATOM   6377  O O   . ILE B 2 412 ? 80.009  96.925  74.126  1.00 240.87 ? 412 ILE B O   1 
ATOM   6378  C CB  . ILE B 2 412 ? 82.360  95.900  76.120  1.00 269.23 ? 412 ILE B CB  1 
ATOM   6379  C CG1 . ILE B 2 412 ? 83.788  95.333  76.111  1.00 267.26 ? 412 ILE B CG1 1 
ATOM   6380  C CG2 . ILE B 2 412 ? 81.314  94.804  75.933  1.00 288.72 ? 412 ILE B CG2 1 
ATOM   6381  C CD1 . ILE B 2 412 ? 84.363  95.020  74.703  1.00 185.25 ? 412 ILE B CD1 1 
ATOM   6382  N N   . ILE B 2 413 ? 80.380  98.630  75.546  1.00 224.73 ? 413 ILE B N   1 
ATOM   6383  C CA  . ILE B 2 413 ? 79.154  99.324  75.157  1.00 249.51 ? 413 ILE B CA  1 
ATOM   6384  C C   . ILE B 2 413 ? 79.217  99.615  73.649  1.00 237.01 ? 413 ILE B C   1 
ATOM   6385  O O   . ILE B 2 413 ? 78.252  99.336  72.925  1.00 269.52 ? 413 ILE B O   1 
ATOM   6386  C CB  . ILE B 2 413 ? 78.905  100.584 76.021  1.00 329.41 ? 413 ILE B CB  1 
ATOM   6387  C CG1 . ILE B 2 413 ? 78.623  100.219 77.485  1.00 379.83 ? 413 ILE B CG1 1 
ATOM   6388  C CG2 . ILE B 2 413 ? 77.776  101.442 75.452  1.00 383.67 ? 413 ILE B CG2 1 
ATOM   6389  C CD1 . ILE B 2 413 ? 78.847  101.349 78.475  1.00 388.18 ? 413 ILE B CD1 1 
ATOM   6390  N N   . GLY B 2 414 ? 80.364  100.147 73.194  1.00 226.51 ? 414 GLY B N   1 
ATOM   6391  C CA  . GLY B 2 414 ? 80.643  100.373 71.783  1.00 221.94 ? 414 GLY B CA  1 
ATOM   6392  C C   . GLY B 2 414 ? 80.534  99.125  70.897  1.00 230.25 ? 414 GLY B C   1 
ATOM   6393  O O   . GLY B 2 414 ? 80.049  99.245  69.775  1.00 280.99 ? 414 GLY B O   1 
ATOM   6394  N N   . MET B 2 415 ? 80.981  97.951  71.384  1.00 234.48 ? 415 MET B N   1 
ATOM   6395  C CA  . MET B 2 415 ? 80.923  96.688  70.648  1.00 232.49 ? 415 MET B CA  1 
ATOM   6396  C C   . MET B 2 415 ? 79.480  96.345  70.253  1.00 256.08 ? 415 MET B C   1 
ATOM   6397  O O   . MET B 2 415 ? 79.244  96.001  69.096  1.00 250.52 ? 415 MET B O   1 
ATOM   6398  C CB  . MET B 2 415 ? 81.550  95.551  71.478  1.00 251.89 ? 415 MET B CB  1 
ATOM   6399  C CG  . MET B 2 415 ? 81.404  94.126  70.933  1.00 225.77 ? 415 MET B CG  1 
ATOM   6400  S SD  . MET B 2 415 ? 82.271  93.895  69.361  1.00 223.70 ? 415 MET B SD  1 
ATOM   6401  C CE  . MET B 2 415 ? 81.345  92.553  68.627  1.00 256.52 ? 415 MET B CE  1 
ATOM   6402  N N   . ILE B 2 416 ? 78.531  96.446  71.198  1.00 289.50 ? 416 ILE B N   1 
ATOM   6403  C CA  . ILE B 2 416 ? 77.118  96.197  70.915  1.00 334.07 ? 416 ILE B CA  1 
ATOM   6404  C C   . ILE B 2 416 ? 76.591  97.280  69.970  1.00 312.80 ? 416 ILE B C   1 
ATOM   6405  O O   . ILE B 2 416 ? 75.975  96.962  68.954  1.00 328.53 ? 416 ILE B O   1 
ATOM   6406  C CB  . ILE B 2 416 ? 76.263  96.126  72.203  1.00 453.81 ? 416 ILE B CB  1 
ATOM   6407  C CG1 . ILE B 2 416 ? 76.774  95.059  73.178  1.00 501.78 ? 416 ILE B CG1 1 
ATOM   6408  C CG2 . ILE B 2 416 ? 74.781  95.912  71.868  1.00 506.71 ? 416 ILE B CG2 1 
ATOM   6409  C CD1 . ILE B 2 416 ? 76.006  94.987  74.478  1.00 531.80 ? 416 ILE B CD1 1 
ATOM   6410  N N   . TRP B 2 417 ? 76.834  98.549  70.326  1.00 279.60 ? 417 TRP B N   1 
ATOM   6411  C CA  . TRP B 2 417 ? 76.331  99.710  69.600  1.00 271.48 ? 417 TRP B CA  1 
ATOM   6412  C C   . TRP B 2 417 ? 76.729  99.650  68.121  1.00 283.76 ? 417 TRP B C   1 
ATOM   6413  O O   . TRP B 2 417 ? 75.880  99.849  67.259  1.00 319.70 ? 417 TRP B O   1 
ATOM   6414  C CB  . TRP B 2 417 ? 76.859  100.964 70.312  1.00 311.81 ? 417 TRP B CB  1 
ATOM   6415  C CG  . TRP B 2 417 ? 76.435  102.335 69.835  1.00 328.64 ? 417 TRP B CG  1 
ATOM   6416  C CD1 . TRP B 2 417 ? 75.511  103.137 70.446  1.00 268.90 ? 417 TRP B CD1 1 
ATOM   6417  C CD2 . TRP B 2 417 ? 76.939  103.094 68.703  1.00 388.68 ? 417 TRP B CD2 1 
ATOM   6418  N NE1 . TRP B 2 417 ? 75.388  104.324 69.774  1.00 272.99 ? 417 TRP B NE1 1 
ATOM   6419  C CE2 . TRP B 2 417 ? 76.246  104.332 68.704  1.00 347.22 ? 417 TRP B CE2 1 
ATOM   6420  C CE3 . TRP B 2 417 ? 77.883  102.857 67.686  1.00 419.36 ? 417 TRP B CE3 1 
ATOM   6421  C CZ2 . TRP B 2 417 ? 76.478  105.317 67.738  1.00 383.70 ? 417 TRP B CZ2 1 
ATOM   6422  C CZ3 . TRP B 2 417 ? 78.109  103.832 66.732  1.00 420.95 ? 417 TRP B CZ3 1 
ATOM   6423  C CH2 . TRP B 2 417 ? 77.423  105.051 66.767  1.00 415.32 ? 417 TRP B CH2 1 
ATOM   6424  N N   . LEU B 2 418 ? 78.004  99.351  67.826  1.00 277.24 ? 418 LEU B N   1 
ATOM   6425  C CA  . LEU B 2 418 ? 78.500  99.326  66.453  1.00 258.21 ? 418 LEU B CA  1 
ATOM   6426  C C   . LEU B 2 418 ? 77.939  98.121  65.680  1.00 281.47 ? 418 LEU B C   1 
ATOM   6427  O O   . LEU B 2 418 ? 77.666  98.263  64.488  1.00 327.07 ? 418 LEU B O   1 
ATOM   6428  C CB  . LEU B 2 418 ? 80.035  99.323  66.483  1.00 290.16 ? 418 LEU B CB  1 
ATOM   6429  C CG  . LEU B 2 418 ? 80.749  99.395  65.131  1.00 316.93 ? 418 LEU B CG  1 
ATOM   6430  C CD1 . LEU B 2 418 ? 80.488  100.738 64.450  1.00 324.29 ? 418 LEU B CD1 1 
ATOM   6431  C CD2 . LEU B 2 418 ? 82.256  99.131  65.273  1.00 352.55 ? 418 LEU B CD2 1 
ATOM   6432  N N   . ARG B 2 419 ? 77.758  96.952  66.326  1.00 277.76 ? 419 ARG B N   1 
ATOM   6433  C CA  . ARG B 2 419 ? 77.179  95.783  65.659  1.00 307.27 ? 419 ARG B CA  1 
ATOM   6434  C C   . ARG B 2 419 ? 75.696  95.996  65.292  1.00 362.38 ? 419 ARG B C   1 
ATOM   6435  O O   . ARG B 2 419 ? 75.232  95.410  64.314  1.00 335.36 ? 419 ARG B O   1 
ATOM   6436  C CB  . ARG B 2 419 ? 77.378  94.517  66.504  1.00 288.90 ? 419 ARG B CB  1 
ATOM   6437  C CG  . ARG B 2 419 ? 77.052  93.230  65.754  1.00 308.96 ? 419 ARG B CG  1 
ATOM   6438  C CD  . ARG B 2 419 ? 77.818  92.027  66.259  1.00 319.30 ? 419 ARG B CD  1 
ATOM   6439  N NE  . ARG B 2 419 ? 77.508  91.732  67.653  1.00 351.53 ? 419 ARG B NE  1 
ATOM   6440  C CZ  . ARG B 2 419 ? 78.133  90.834  68.415  1.00 396.09 ? 419 ARG B CZ  1 
ATOM   6441  N NH1 . ARG B 2 419 ? 77.710  90.630  69.654  1.00 360.94 ? 419 ARG B NH1 1 
ATOM   6442  N NH2 . ARG B 2 419 ? 79.166  90.138  67.958  1.00 420.77 ? 419 ARG B NH2 1 
ATOM   6443  N N   . HIS B 2 420 ? 74.954  96.823  66.050  1.00 389.63 ? 420 HIS B N   1 
ATOM   6444  C CA  . HIS B 2 420 ? 73.593  97.230  65.698  1.00 368.82 ? 420 HIS B CA  1 
ATOM   6445  C C   . HIS B 2 420 ? 73.575  98.379  64.683  1.00 324.25 ? 420 HIS B C   1 
ATOM   6446  O O   . HIS B 2 420 ? 72.755  98.360  63.766  1.00 294.58 ? 420 HIS B O   1 
ATOM   6447  C CB  . HIS B 2 420 ? 72.799  97.610  66.957  1.00 406.73 ? 420 HIS B CB  1 
ATOM   6448  C CG  . HIS B 2 420 ? 72.473  96.458  67.856  1.00 457.77 ? 420 HIS B CG  1 
ATOM   6449  N ND1 . HIS B 2 420 ? 71.769  96.595  69.036  1.00 436.55 ? 420 HIS B ND1 1 
ATOM   6450  C CD2 . HIS B 2 420 ? 72.755  95.152  67.746  1.00 496.44 ? 420 HIS B CD2 1 
ATOM   6451  C CE1 . HIS B 2 420 ? 71.633  95.408  69.612  1.00 407.68 ? 420 HIS B CE1 1 
ATOM   6452  N NE2 . HIS B 2 420 ? 72.224  94.516  68.844  1.00 468.55 ? 420 HIS B NE2 1 
ATOM   6453  N N   . ARG B 2 421 ? 74.468  99.370  64.849  1.00 345.43 ? 421 ARG B N   1 
ATOM   6454  C CA  . ARG B 2 421 ? 74.443  100.612 64.081  1.00 356.71 ? 421 ARG B CA  1 
ATOM   6455  C C   . ARG B 2 421 ? 75.037  100.464 62.670  1.00 343.28 ? 421 ARG B C   1 
ATOM   6456  O O   . ARG B 2 421 ? 74.598  101.203 61.785  1.00 366.69 ? 421 ARG B O   1 
ATOM   6457  C CB  . ARG B 2 421 ? 75.177  101.717 64.862  1.00 357.71 ? 421 ARG B CB  1 
ATOM   6458  C CG  . ARG B 2 421 ? 75.064  103.117 64.277  1.00 311.14 ? 421 ARG B CG  1 
ATOM   6459  C CD  . ARG B 2 421 ? 73.630  103.615 64.166  1.00 263.60 ? 421 ARG B CD  1 
ATOM   6460  N NE  . ARG B 2 421 ? 73.528  104.888 63.459  1.00 311.00 ? 421 ARG B NE  1 
ATOM   6461  C CZ  . ARG B 2 421 ? 73.484  105.050 62.132  1.00 410.97 ? 421 ARG B CZ  1 
ATOM   6462  N NH1 . ARG B 2 421 ? 73.422  106.270 61.621  1.00 385.22 ? 421 ARG B NH1 1 
ATOM   6463  N NH2 . ARG B 2 421 ? 73.499  104.006 61.315  1.00 493.99 ? 421 ARG B NH2 1 
ATOM   6464  N N   . LYS B 2 422 ? 76.014  99.547  62.473  1.00 305.65 ? 422 LYS B N   1 
ATOM   6465  C CA  . LYS B 2 422 ? 76.700  99.316  61.198  1.00 288.25 ? 422 LYS B CA  1 
ATOM   6466  C C   . LYS B 2 422 ? 76.894  97.810  60.974  1.00 288.31 ? 422 LYS B C   1 
ATOM   6467  O O   . LYS B 2 422 ? 78.023  97.297  60.983  1.00 246.95 ? 422 LYS B O   1 
ATOM   6468  C CB  . LYS B 2 422 ? 78.037  100.070 61.163  1.00 298.79 ? 422 LYS B CB  1 
ATOM   6469  C CG  . LYS B 2 422 ? 77.891  101.588 61.133  1.00 305.28 ? 422 LYS B CG  1 
ATOM   6470  C CD  . LYS B 2 422 ? 79.211  102.318 61.039  1.00 356.56 ? 422 LYS B CD  1 
ATOM   6471  C CE  . LYS B 2 422 ? 79.074  103.817 61.203  1.00 367.31 ? 422 LYS B CE  1 
ATOM   6472  N NZ  . LYS B 2 422 ? 80.397  104.484 61.188  1.00 384.43 ? 422 LYS B NZ  1 
ATOM   6473  N N   . PRO B 2 423 ? 75.796  97.045  60.750  1.00 321.46 ? 423 PRO B N   1 
ATOM   6474  C CA  . PRO B 2 423 ? 75.866  95.577  60.682  1.00 331.30 ? 423 PRO B CA  1 
ATOM   6475  C C   . PRO B 2 423 ? 76.562  94.979  59.450  1.00 320.48 ? 423 PRO B C   1 
ATOM   6476  O O   . PRO B 2 423 ? 76.825  93.777  59.437  1.00 286.23 ? 423 PRO B O   1 
ATOM   6477  C CB  . PRO B 2 423 ? 74.380  95.161  60.719  1.00 345.86 ? 423 PRO B CB  1 
ATOM   6478  C CG  . PRO B 2 423 ? 73.644  96.339  60.120  1.00 371.11 ? 423 PRO B CG  1 
ATOM   6479  C CD  . PRO B 2 423 ? 74.432  97.559  60.546  1.00 339.53 ? 423 PRO B CD  1 
ATOM   6480  N N   . GLU B 2 424 ? 76.859  95.809  58.434  1.00 341.72 ? 424 GLU B N   1 
ATOM   6481  C CA  . GLU B 2 424 ? 77.521  95.371  57.206  1.00 409.17 ? 424 GLU B CA  1 
ATOM   6482  C C   . GLU B 2 424 ? 79.020  95.070  57.394  1.00 399.27 ? 424 GLU B C   1 
ATOM   6483  O O   . GLU B 2 424 ? 79.594  94.383  56.542  1.00 362.39 ? 424 GLU B O   1 
ATOM   6484  C CB  . GLU B 2 424 ? 77.307  96.391  56.074  1.00 492.23 ? 424 GLU B CB  1 
ATOM   6485  C CG  . GLU B 2 424 ? 77.937  97.775  56.275  1.00 534.71 ? 424 GLU B CG  1 
ATOM   6486  C CD  . GLU B 2 424 ? 77.074  98.824  56.962  1.00 534.98 ? 424 GLU B CD  1 
ATOM   6487  O OE1 . GLU B 2 424 ? 76.419  98.482  57.968  1.00 496.73 ? 424 GLU B OE1 1 
ATOM   6488  O OE2 . GLU B 2 424 ? 77.061  99.986  56.497  1.00 559.17 ? 424 GLU B OE2 1 
ATOM   6489  N N   . LEU B 2 425 ? 79.652  95.579  58.474  1.00 384.12 ? 425 LEU B N   1 
ATOM   6490  C CA  . LEU B 2 425 ? 81.070  95.359  58.736  1.00 330.77 ? 425 LEU B CA  1 
ATOM   6491  C C   . LEU B 2 425 ? 81.335  93.893  59.082  1.00 297.52 ? 425 LEU B C   1 
ATOM   6492  O O   . LEU B 2 425 ? 80.577  93.274  59.835  1.00 231.10 ? 425 LEU B O   1 
ATOM   6493  C CB  . LEU B 2 425 ? 81.528  96.278  59.877  1.00 274.53 ? 425 LEU B CB  1 
ATOM   6494  C CG  . LEU B 2 425 ? 81.529  97.770  59.562  1.00 293.78 ? 425 LEU B CG  1 
ATOM   6495  C CD1 . LEU B 2 425 ? 81.779  98.610  60.805  1.00 331.62 ? 425 LEU B CD1 1 
ATOM   6496  C CD2 . LEU B 2 425 ? 82.580  98.071  58.505  1.00 310.65 ? 425 LEU B CD2 1 
ATOM   6497  N N   . GLU B 2 426 ? 82.440  93.370  58.524  1.00 311.44 ? 426 GLU B N   1 
ATOM   6498  C CA  . GLU B 2 426 ? 82.794  91.958  58.619  1.00 325.46 ? 426 GLU B CA  1 
ATOM   6499  C C   . GLU B 2 426 ? 83.062  91.524  60.065  1.00 306.04 ? 426 GLU B C   1 
ATOM   6500  O O   . GLU B 2 426 ? 83.526  92.315  60.883  1.00 350.62 ? 426 GLU B O   1 
ATOM   6501  C CB  . GLU B 2 426 ? 84.013  91.632  57.740  1.00 336.31 ? 426 GLU B CB  1 
ATOM   6502  C CG  . GLU B 2 426 ? 83.640  91.042  56.390  1.00 410.25 ? 426 GLU B CG  1 
ATOM   6503  C CD  . GLU B 2 426 ? 82.968  89.675  56.434  1.00 452.31 ? 426 GLU B CD  1 
ATOM   6504  O OE1 . GLU B 2 426 ? 82.824  89.107  57.542  1.00 460.07 ? 426 GLU B OE1 1 
ATOM   6505  O OE2 . GLU B 2 426 ? 82.584  89.177  55.357  1.00 474.06 ? 426 GLU B OE2 1 
ATOM   6506  N N   . ARG B 2 427 ? 82.772  90.242  60.356  1.00 285.66 ? 427 ARG B N   1 
ATOM   6507  C CA  . ARG B 2 427 ? 82.935  89.633  61.671  1.00 258.60 ? 427 ARG B CA  1 
ATOM   6508  C C   . ARG B 2 427 ? 83.666  88.298  61.494  1.00 222.48 ? 427 ARG B C   1 
ATOM   6509  O O   . ARG B 2 427 ? 83.051  87.235  61.577  1.00 284.12 ? 427 ARG B O   1 
ATOM   6510  C CB  . ARG B 2 427 ? 81.564  89.437  62.339  1.00 304.49 ? 427 ARG B CB  1 
ATOM   6511  C CG  . ARG B 2 427 ? 80.617  90.629  62.319  1.00 298.79 ? 427 ARG B CG  1 
ATOM   6512  C CD  . ARG B 2 427 ? 81.071  91.792  63.168  1.00 294.54 ? 427 ARG B CD  1 
ATOM   6513  N NE  . ARG B 2 427 ? 80.378  93.025  62.807  1.00 297.02 ? 427 ARG B NE  1 
ATOM   6514  C CZ  . ARG B 2 427 ? 80.267  94.120  63.571  1.00 288.57 ? 427 ARG B CZ  1 
ATOM   6515  N NH1 . ARG B 2 427 ? 79.663  95.197  63.092  1.00 261.07 ? 427 ARG B NH1 1 
ATOM   6516  N NH2 . ARG B 2 427 ? 80.738  94.157  64.811  1.00 276.38 ? 427 ARG B NH2 1 
ATOM   6517  N N   . PRO B 2 428 ? 84.991  88.286  61.220  1.00 288.96 ? 428 PRO B N   1 
ATOM   6518  C CA  . PRO B 2 428 ? 85.749  87.040  61.022  1.00 341.27 ? 428 PRO B CA  1 
ATOM   6519  C C   . PRO B 2 428 ? 85.668  86.021  62.164  1.00 327.03 ? 428 PRO B C   1 
ATOM   6520  O O   . PRO B 2 428 ? 85.780  84.825  61.900  1.00 287.88 ? 428 PRO B O   1 
ATOM   6521  C CB  . PRO B 2 428 ? 87.196  87.533  60.839  1.00 412.62 ? 428 PRO B CB  1 
ATOM   6522  C CG  . PRO B 2 428 ? 87.012  88.917  60.272  1.00 443.72 ? 428 PRO B CG  1 
ATOM   6523  C CD  . PRO B 2 428 ? 85.843  89.471  61.057  1.00 400.99 ? 428 PRO B CD  1 
ATOM   6524  N N   . ILE B 2 429 ? 85.474  86.500  63.409  1.00 335.49 ? 429 ILE B N   1 
ATOM   6525  C CA  . ILE B 2 429 ? 84.861  85.707  64.476  1.00 363.40 ? 429 ILE B CA  1 
ATOM   6526  C C   . ILE B 2 429 ? 83.759  86.551  65.143  1.00 299.36 ? 429 ILE B C   1 
ATOM   6527  O O   . ILE B 2 429 ? 83.916  87.749  65.380  1.00 184.06 ? 429 ILE B O   1 
ATOM   6528  C CB  . ILE B 2 429 ? 85.917  85.128  65.458  1.00 414.49 ? 429 ILE B CB  1 
ATOM   6529  C CG1 . ILE B 2 429 ? 86.749  84.030  64.778  1.00 416.77 ? 429 ILE B CG1 1 
ATOM   6530  C CG2 . ILE B 2 429 ? 85.287  84.631  66.761  1.00 404.67 ? 429 ILE B CG2 1 
ATOM   6531  C CD1 . ILE B 2 429 ? 87.788  83.346  65.652  1.00 436.51 ? 429 ILE B CD1 1 
ATOM   6532  N N   . LYS B 2 430 ? 82.627  85.883  65.418  1.00 348.52 ? 430 LYS B N   1 
ATOM   6533  C CA  . LYS B 2 430 ? 81.508  86.398  66.189  1.00 374.42 ? 430 LYS B CA  1 
ATOM   6534  C C   . LYS B 2 430 ? 81.084  85.291  67.149  1.00 430.06 ? 430 LYS B C   1 
ATOM   6535  O O   . LYS B 2 430 ? 80.989  84.130  66.743  1.00 428.00 ? 430 LYS B O   1 
ATOM   6536  C CB  . LYS B 2 430 ? 80.367  86.801  65.252  1.00 391.70 ? 430 LYS B CB  1 
ATOM   6537  C CG  . LYS B 2 430 ? 79.038  87.158  65.904  1.00 409.85 ? 430 LYS B CG  1 
ATOM   6538  C CD  . LYS B 2 430 ? 78.026  87.724  64.923  1.00 408.85 ? 430 LYS B CD  1 
ATOM   6539  C CE  . LYS B 2 430 ? 76.687  88.063  65.550  1.00 397.56 ? 430 LYS B CE  1 
ATOM   6540  N NZ  . LYS B 2 430 ? 75.932  86.863  65.990  1.00 400.01 ? 430 LYS B NZ  1 
ATOM   6541  N N   . VAL B 2 431 ? 80.825  85.661  68.413  1.00 457.48 ? 431 VAL B N   1 
ATOM   6542  C CA  . VAL B 2 431 ? 80.685  84.684  69.486  1.00 466.58 ? 431 VAL B CA  1 
ATOM   6543  C C   . VAL B 2 431 ? 79.252  84.721  70.028  1.00 386.26 ? 431 VAL B C   1 
ATOM   6544  O O   . VAL B 2 431 ? 78.557  83.703  69.978  1.00 355.78 ? 431 VAL B O   1 
ATOM   6545  C CB  . VAL B 2 431 ? 81.753  84.881  70.584  1.00 511.36 ? 431 VAL B CB  1 
ATOM   6546  C CG1 . VAL B 2 431 ? 81.585  83.890  71.733  1.00 507.52 ? 431 VAL B CG1 1 
ATOM   6547  C CG2 . VAL B 2 431 ? 83.164  84.789  70.012  1.00 510.61 ? 431 VAL B CG2 1 
ATOM   6548  N N   . ASN B 2 432 ? 78.814  85.880  70.548  1.00 299.33 ? 432 ASN B N   1 
ATOM   6549  C CA  . ASN B 2 432 ? 77.523  85.975  71.223  1.00 305.62 ? 432 ASN B CA  1 
ATOM   6550  C C   . ASN B 2 432 ? 77.138  87.443  71.438  1.00 283.84 ? 432 ASN B C   1 
ATOM   6551  O O   . ASN B 2 432 ? 77.987  88.326  71.317  1.00 228.99 ? 432 ASN B O   1 
ATOM   6552  C CB  . ASN B 2 432 ? 77.542  85.205  72.554  1.00 317.18 ? 432 ASN B CB  1 
ATOM   6553  C CG  . ASN B 2 432 ? 76.209  84.577  72.894  1.00 322.50 ? 432 ASN B CG  1 
ATOM   6554  O OD1 . ASN B 2 432 ? 75.241  85.288  73.161  1.00 344.58 ? 432 ASN B OD1 1 
ATOM   6555  N ND2 . ASN B 2 432 ? 76.154  83.255  72.883  1.00 333.61 ? 432 ASN B ND2 1 
ATOM   6556  N N   . LEU B 2 433 ? 75.852  87.696  71.755  1.00 304.59 ? 433 LEU B N   1 
ATOM   6557  C CA  . LEU B 2 433 ? 75.390  89.004  72.224  1.00 303.36 ? 433 LEU B CA  1 
ATOM   6558  C C   . LEU B 2 433 ? 75.241  89.035  73.755  1.00 298.05 ? 433 LEU B C   1 
ATOM   6559  O O   . LEU B 2 433 ? 75.055  90.122  74.300  1.00 251.28 ? 433 LEU B O   1 
ATOM   6560  C CB  . LEU B 2 433 ? 74.091  89.410  71.498  1.00 340.77 ? 433 LEU B CB  1 
ATOM   6561  C CG  . LEU B 2 433 ? 72.739  88.889  72.014  1.00 381.57 ? 433 LEU B CG  1 
ATOM   6562  C CD1 . LEU B 2 433 ? 71.588  89.659  71.375  1.00 377.40 ? 433 LEU B CD1 1 
ATOM   6563  C CD2 . LEU B 2 433 ? 72.562  87.393  71.770  1.00 387.05 ? 433 LEU B CD2 1 
ATOM   6564  N N   . ALA B 2 434 ? 75.329  87.879  74.449  1.00 320.85 ? 434 ALA B N   1 
ATOM   6565  C CA  . ALA B 2 434 ? 75.176  87.792  75.899  1.00 342.02 ? 434 ALA B CA  1 
ATOM   6566  C C   . ALA B 2 434 ? 76.448  88.226  76.634  1.00 301.62 ? 434 ALA B C   1 
ATOM   6567  O O   . ALA B 2 434 ? 76.343  88.963  77.615  1.00 255.02 ? 434 ALA B O   1 
ATOM   6568  C CB  . ALA B 2 434 ? 74.777  86.389  76.299  1.00 383.05 ? 434 ALA B CB  1 
ATOM   6569  N N   . LEU B 2 435 ? 77.634  87.778  76.173  1.00 277.61 ? 435 LEU B N   1 
ATOM   6570  C CA  . LEU B 2 435 ? 78.902  88.058  76.848  1.00 229.19 ? 435 LEU B CA  1 
ATOM   6571  C C   . LEU B 2 435 ? 79.139  89.569  76.955  1.00 229.84 ? 435 LEU B C   1 
ATOM   6572  O O   . LEU B 2 435 ? 79.472  90.022  78.051  1.00 330.37 ? 435 LEU B O   1 
ATOM   6573  C CB  . LEU B 2 435 ? 80.082  87.357  76.148  1.00 225.34 ? 435 LEU B CB  1 
ATOM   6574  C CG  . LEU B 2 435 ? 80.042  85.827  76.070  1.00 301.10 ? 435 LEU B CG  1 
ATOM   6575  C CD1 . LEU B 2 435 ? 81.354  85.300  75.497  1.00 271.29 ? 435 LEU B CD1 1 
ATOM   6576  C CD2 . LEU B 2 435 ? 79.755  85.181  77.427  1.00 344.40 ? 435 LEU B CD2 1 
ATOM   6577  N N   . PRO B 2 436 ? 78.987  90.400  75.888  1.00 256.28 ? 436 PRO B N   1 
ATOM   6578  C CA  . PRO B 2 436 ? 78.999  91.861  76.037  1.00 284.37 ? 436 PRO B CA  1 
ATOM   6579  C C   . PRO B 2 436 ? 78.042  92.401  77.104  1.00 271.55 ? 436 PRO B C   1 
ATOM   6580  O O   . PRO B 2 436 ? 78.474  93.196  77.925  1.00 229.11 ? 436 PRO B O   1 
ATOM   6581  C CB  . PRO B 2 436 ? 78.608  92.394  74.647  1.00 310.93 ? 436 PRO B CB  1 
ATOM   6582  C CG  . PRO B 2 436 ? 79.003  91.294  73.694  1.00 332.57 ? 436 PRO B CG  1 
ATOM   6583  C CD  . PRO B 2 436 ? 78.819  90.013  74.479  1.00 309.29 ? 436 PRO B CD  1 
ATOM   6584  N N   . VAL B 2 437 ? 76.771  91.973  77.117  1.00 296.69 ? 437 VAL B N   1 
ATOM   6585  C CA  . VAL B 2 437 ? 75.778  92.513  78.047  1.00 336.21 ? 437 VAL B CA  1 
ATOM   6586  C C   . VAL B 2 437 ? 76.161  92.174  79.495  1.00 292.20 ? 437 VAL B C   1 
ATOM   6587  O O   . VAL B 2 437 ? 76.110  93.058  80.355  1.00 237.29 ? 437 VAL B O   1 
ATOM   6588  C CB  . VAL B 2 437 ? 74.349  92.043  77.687  1.00 391.46 ? 437 VAL B CB  1 
ATOM   6589  C CG1 . VAL B 2 437 ? 73.317  92.371  78.763  1.00 463.05 ? 437 VAL B CG1 1 
ATOM   6590  C CG2 . VAL B 2 437 ? 73.894  92.612  76.346  1.00 314.42 ? 437 VAL B CG2 1 
ATOM   6591  N N   . PHE B 2 438 ? 76.541  90.909  79.752  1.00 275.80 ? 438 PHE B N   1 
ATOM   6592  C CA  . PHE B 2 438 ? 76.996  90.465  81.066  1.00 292.94 ? 438 PHE B CA  1 
ATOM   6593  C C   . PHE B 2 438 ? 78.219  91.274  81.517  1.00 292.19 ? 438 PHE B C   1 
ATOM   6594  O O   . PHE B 2 438 ? 78.276  91.713  82.664  1.00 266.55 ? 438 PHE B O   1 
ATOM   6595  C CB  . PHE B 2 438 ? 77.298  88.958  81.066  1.00 323.61 ? 438 PHE B CB  1 
ATOM   6596  C CG  . PHE B 2 438 ? 77.976  88.460  82.322  1.00 407.73 ? 438 PHE B CG  1 
ATOM   6597  C CD1 . PHE B 2 438 ? 77.248  88.199  83.477  1.00 433.18 ? 438 PHE B CD1 1 
ATOM   6598  C CD2 . PHE B 2 438 ? 79.354  88.267  82.362  1.00 437.08 ? 438 PHE B CD2 1 
ATOM   6599  C CE1 . PHE B 2 438 ? 77.877  87.747  84.634  1.00 397.64 ? 438 PHE B CE1 1 
ATOM   6600  C CE2 . PHE B 2 438 ? 79.983  87.818  83.519  1.00 412.87 ? 438 PHE B CE2 1 
ATOM   6601  C CZ  . PHE B 2 438 ? 79.244  87.557  84.655  1.00 358.30 ? 438 PHE B CZ  1 
ATOM   6602  N N   . PHE B 2 439 ? 79.198  91.470  80.623  1.00 300.02 ? 439 PHE B N   1 
ATOM   6603  C CA  . PHE B 2 439 ? 80.394  92.227  80.957  1.00 254.14 ? 439 PHE B CA  1 
ATOM   6604  C C   . PHE B 2 439 ? 80.027  93.687  81.259  1.00 249.51 ? 439 PHE B C   1 
ATOM   6605  O O   . PHE B 2 439 ? 80.557  94.230  82.219  1.00 300.74 ? 439 PHE B O   1 
ATOM   6606  C CB  . PHE B 2 439 ? 81.444  92.072  79.848  1.00 242.26 ? 439 PHE B CB  1 
ATOM   6607  C CG  . PHE B 2 439 ? 82.721  92.798  80.152  1.00 238.89 ? 439 PHE B CG  1 
ATOM   6608  C CD1 . PHE B 2 439 ? 82.848  94.174  79.926  1.00 299.49 ? 439 PHE B CD1 1 
ATOM   6609  C CD2 . PHE B 2 439 ? 83.785  92.108  80.688  1.00 208.61 ? 439 PHE B CD2 1 
ATOM   6610  C CE1 . PHE B 2 439 ? 84.026  94.845  80.228  1.00 261.04 ? 439 PHE B CE1 1 
ATOM   6611  C CE2 . PHE B 2 439 ? 84.964  92.776  80.991  1.00 324.45 ? 439 PHE B CE2 1 
ATOM   6612  C CZ  . PHE B 2 439 ? 85.085  94.135  80.764  1.00 348.63 ? 439 PHE B CZ  1 
ATOM   6613  N N   . ILE B 2 440 ? 79.141  94.323  80.470  1.00 230.50 ? 440 ILE B N   1 
ATOM   6614  C CA  . ILE B 2 440 ? 78.756  95.722  80.677  1.00 261.11 ? 440 ILE B CA  1 
ATOM   6615  C C   . ILE B 2 440 ? 78.081  95.898  82.039  1.00 288.18 ? 440 ILE B C   1 
ATOM   6616  O O   . ILE B 2 440 ? 78.477  96.792  82.789  1.00 247.63 ? 440 ILE B O   1 
ATOM   6617  C CB  . ILE B 2 440 ? 77.868  96.269  79.536  1.00 318.06 ? 440 ILE B CB  1 
ATOM   6618  C CG1 . ILE B 2 440 ? 78.641  96.373  78.219  1.00 326.38 ? 440 ILE B CG1 1 
ATOM   6619  C CG2 . ILE B 2 440 ? 77.247  97.619  79.901  1.00 355.22 ? 440 ILE B CG2 1 
ATOM   6620  C CD1 . ILE B 2 440 ? 77.757  96.442  76.999  1.00 306.05 ? 440 ILE B CD1 1 
ATOM   6621  N N   . LEU B 2 441 ? 77.073  95.071  82.362  1.00 330.03 ? 441 LEU B N   1 
ATOM   6622  C CA  . LEU B 2 441 ? 76.376  95.241  83.635  1.00 373.41 ? 441 LEU B CA  1 
ATOM   6623  C C   . LEU B 2 441 ? 77.333  94.938  84.801  1.00 348.60 ? 441 LEU B C   1 
ATOM   6624  O O   . LEU B 2 441 ? 77.259  95.610  85.829  1.00 377.76 ? 441 LEU B O   1 
ATOM   6625  C CB  . LEU B 2 441 ? 75.066  94.431  83.666  1.00 417.64 ? 441 LEU B CB  1 
ATOM   6626  C CG  . LEU B 2 441 ? 75.142  92.901  83.717  1.00 452.58 ? 441 LEU B CG  1 
ATOM   6627  C CD1 . LEU B 2 441 ? 75.209  92.375  85.149  1.00 464.25 ? 441 LEU B CD1 1 
ATOM   6628  C CD2 . LEU B 2 441 ? 73.948  92.277  83.007  1.00 465.39 ? 441 LEU B CD2 1 
ATOM   6629  N N   . ALA B 2 442 ? 78.235  93.955  84.640  1.00 287.68 ? 442 ALA B N   1 
ATOM   6630  C CA  . ALA B 2 442 ? 79.259  93.644  85.632  1.00 251.81 ? 442 ALA B CA  1 
ATOM   6631  C C   . ALA B 2 442 ? 80.206  94.829  85.862  1.00 252.30 ? 442 ALA B C   1 
ATOM   6632  O O   . ALA B 2 442 ? 80.374  95.263  86.994  1.00 275.55 ? 442 ALA B O   1 
ATOM   6633  C CB  . ALA B 2 442 ? 80.015  92.399  85.216  1.00 219.53 ? 442 ALA B CB  1 
ATOM   6634  N N   . CYS B 2 443 ? 80.834  95.363  84.811  1.00 279.64 ? 443 CYS B N   1 
ATOM   6635  C CA  . CYS B 2 443 ? 81.833  96.414  84.986  1.00 303.31 ? 443 CYS B CA  1 
ATOM   6636  C C   . CYS B 2 443 ? 81.159  97.695  85.493  1.00 296.10 ? 443 CYS B C   1 
ATOM   6637  O O   . CYS B 2 443 ? 81.732  98.362  86.348  1.00 316.28 ? 443 CYS B O   1 
ATOM   6638  C CB  . CYS B 2 443 ? 82.657  96.631  83.714  1.00 352.30 ? 443 CYS B CB  1 
ATOM   6639  S SG  . CYS B 2 443 ? 81.691  97.105  82.264  1.00 397.00 ? 443 CYS B SG  1 
ATOM   6640  N N   . LEU B 2 444 ? 79.948  98.021  85.003  1.00 263.98 ? 444 LEU B N   1 
ATOM   6641  C CA  . LEU B 2 444 ? 79.233  99.199  85.487  1.00 283.39 ? 444 LEU B CA  1 
ATOM   6642  C C   . LEU B 2 444 ? 78.819  99.031  86.953  1.00 287.52 ? 444 LEU B C   1 
ATOM   6643  O O   . LEU B 2 444 ? 78.806  100.030 87.669  1.00 293.45 ? 444 LEU B O   1 
ATOM   6644  C CB  . LEU B 2 444 ? 78.031  99.501  84.581  1.00 329.85 ? 444 LEU B CB  1 
ATOM   6645  C CG  . LEU B 2 444 ? 78.369  100.096 83.209  1.00 381.51 ? 444 LEU B CG  1 
ATOM   6646  C CD1 . LEU B 2 444 ? 77.117  100.243 82.356  1.00 430.14 ? 444 LEU B CD1 1 
ATOM   6647  C CD2 . LEU B 2 444 ? 79.067  101.450 83.333  1.00 364.53 ? 444 LEU B CD2 1 
ATOM   6648  N N   . PHE B 2 445 ? 78.499  97.801  87.403  1.00 328.19 ? 445 PHE B N   1 
ATOM   6649  C CA  . PHE B 2 445 ? 78.318  97.509  88.827  1.00 357.09 ? 445 PHE B CA  1 
ATOM   6650  C C   . PHE B 2 445 ? 79.607  97.845  89.588  1.00 249.54 ? 445 PHE B C   1 
ATOM   6651  O O   . PHE B 2 445 ? 79.550  98.659  90.506  1.00 210.19 ? 445 PHE B O   1 
ATOM   6652  C CB  . PHE B 2 445 ? 77.830  96.068  89.069  1.00 382.60 ? 445 PHE B CB  1 
ATOM   6653  C CG  . PHE B 2 445 ? 78.054  95.520  90.463  1.00 350.06 ? 445 PHE B CG  1 
ATOM   6654  C CD1 . PHE B 2 445 ? 77.506  96.152  91.570  1.00 362.75 ? 445 PHE B CD1 1 
ATOM   6655  C CD2 . PHE B 2 445 ? 78.813  94.373  90.674  1.00 308.52 ? 445 PHE B CD2 1 
ATOM   6656  C CE1 . PHE B 2 445 ? 77.715  95.653  92.850  1.00 348.47 ? 445 PHE B CE1 1 
ATOM   6657  C CE2 . PHE B 2 445 ? 79.021  93.874  91.953  1.00 274.16 ? 445 PHE B CE2 1 
ATOM   6658  C CZ  . PHE B 2 445 ? 78.471  94.515  93.041  1.00 282.12 ? 445 PHE B CZ  1 
ATOM   6659  N N   . LEU B 2 446 ? 80.736  97.235  89.193  1.00 205.12 ? 446 LEU B N   1 
ATOM   6660  C CA  . LEU B 2 446 ? 82.042  97.461  89.815  1.00 248.88 ? 446 LEU B CA  1 
ATOM   6661  C C   . LEU B 2 446 ? 82.402  98.954  89.898  1.00 262.83 ? 446 LEU B C   1 
ATOM   6662  O O   . LEU B 2 446 ? 82.925  99.394  90.927  1.00 357.06 ? 446 LEU B O   1 
ATOM   6663  C CB  . LEU B 2 446 ? 83.130  96.674  89.054  1.00 261.72 ? 446 LEU B CB  1 
ATOM   6664  C CG  . LEU B 2 446 ? 83.480  95.273  89.574  1.00 286.60 ? 446 LEU B CG  1 
ATOM   6665  C CD1 . LEU B 2 446 ? 84.002  95.326  91.008  1.00 311.37 ? 446 LEU B CD1 1 
ATOM   6666  C CD2 . LEU B 2 446 ? 82.304  94.306  89.487  1.00 286.38 ? 446 LEU B CD2 1 
ATOM   6667  N N   . ILE B 2 447 ? 82.123  99.730  88.837  1.00 248.90 ? 447 ILE B N   1 
ATOM   6668  C CA  . ILE B 2 447 ? 82.413  101.161 88.806  1.00 278.33 ? 447 ILE B CA  1 
ATOM   6669  C C   . ILE B 2 447 ? 81.476  101.912 89.762  1.00 350.40 ? 447 ILE B C   1 
ATOM   6670  O O   . ILE B 2 447 ? 81.961  102.659 90.616  1.00 343.55 ? 447 ILE B O   1 
ATOM   6671  C CB  . ILE B 2 447 ? 82.345  101.700 87.357  1.00 292.42 ? 447 ILE B CB  1 
ATOM   6672  C CG1 . ILE B 2 447 ? 83.410  101.050 86.466  1.00 297.15 ? 447 ILE B CG1 1 
ATOM   6673  C CG2 . ILE B 2 447 ? 82.453  103.224 87.311  1.00 332.29 ? 447 ILE B CG2 1 
ATOM   6674  C CD1 . ILE B 2 447 ? 83.065  101.016 84.988  1.00 252.85 ? 447 ILE B CD1 1 
ATOM   6675  N N   . ALA B 2 448 ? 80.151  101.710 89.619  1.00 383.52 ? 448 ALA B N   1 
ATOM   6676  C CA  . ALA B 2 448 ? 79.146  102.463 90.367  1.00 370.74 ? 448 ALA B CA  1 
ATOM   6677  C C   . ALA B 2 448 ? 79.280  102.220 91.874  1.00 332.74 ? 448 ALA B C   1 
ATOM   6678  O O   . ALA B 2 448 ? 79.194  103.170 92.659  1.00 333.66 ? 448 ALA B O   1 
ATOM   6679  C CB  . ALA B 2 448 ? 77.752  102.124 89.876  1.00 351.45 ? 448 ALA B CB  1 
ATOM   6680  N N   . VAL B 2 449 ? 79.503  100.955 92.267  1.00 297.58 ? 449 VAL B N   1 
ATOM   6681  C CA  . VAL B 2 449 ? 79.575  100.571 93.673  1.00 335.45 ? 449 VAL B CA  1 
ATOM   6682  C C   . VAL B 2 449 ? 80.879  101.075 94.319  1.00 359.27 ? 449 VAL B C   1 
ATOM   6683  O O   . VAL B 2 449 ? 80.836  101.582 95.442  1.00 380.26 ? 449 VAL B O   1 
ATOM   6684  C CB  . VAL B 2 449 ? 79.350  99.051  93.840  1.00 272.71 ? 449 VAL B CB  1 
ATOM   6685  C CG1 . VAL B 2 449 ? 80.531  98.228  93.379  1.00 220.30 ? 449 VAL B CG1 1 
ATOM   6686  C CG2 . VAL B 2 449 ? 78.988  98.695  95.277  1.00 354.43 ? 449 VAL B CG2 1 
ATOM   6687  N N   . SER B 2 450 ? 82.029  100.960 93.633  1.00 352.62 ? 450 SER B N   1 
ATOM   6688  C CA  . SER B 2 450 ? 83.293  101.455 94.171  1.00 341.35 ? 450 SER B CA  1 
ATOM   6689  C C   . SER B 2 450 ? 83.294  102.987 94.250  1.00 355.23 ? 450 SER B C   1 
ATOM   6690  O O   . SER B 2 450 ? 83.829  103.535 95.217  1.00 447.88 ? 450 SER B O   1 
ATOM   6691  C CB  . SER B 2 450 ? 84.478  100.929 93.394  1.00 383.31 ? 450 SER B CB  1 
ATOM   6692  O OG  . SER B 2 450 ? 84.450  101.369 92.045  1.00 420.11 ? 450 SER B OG  1 
ATOM   6693  N N   . PHE B 2 451 ? 82.688  103.671 93.258  1.00 378.32 ? 451 PHE B N   1 
ATOM   6694  C CA  . PHE B 2 451 ? 82.473  105.116 93.305  1.00 446.46 ? 451 PHE B CA  1 
ATOM   6695  C C   . PHE B 2 451 ? 81.649  105.513 94.537  1.00 516.34 ? 451 PHE B C   1 
ATOM   6696  O O   . PHE B 2 451 ? 82.061  106.401 95.284  1.00 554.73 ? 451 PHE B O   1 
ATOM   6697  C CB  . PHE B 2 451 ? 81.838  105.612 91.998  1.00 444.25 ? 451 PHE B CB  1 
ATOM   6698  C CG  . PHE B 2 451 ? 81.699  107.112 91.883  1.00 458.57 ? 451 PHE B CG  1 
ATOM   6699  C CD1 . PHE B 2 451 ? 80.685  107.790 92.556  1.00 449.62 ? 451 PHE B CD1 1 
ATOM   6700  C CD2 . PHE B 2 451 ? 82.578  107.852 91.103  1.00 480.37 ? 451 PHE B CD2 1 
ATOM   6701  C CE1 . PHE B 2 451 ? 80.556  109.169 92.449  1.00 456.36 ? 451 PHE B CE1 1 
ATOM   6702  C CE2 . PHE B 2 451 ? 82.452  109.231 91.000  1.00 490.66 ? 451 PHE B CE2 1 
ATOM   6703  C CZ  . PHE B 2 451 ? 81.440  109.888 91.671  1.00 484.83 ? 451 PHE B CZ  1 
ATOM   6704  N N   . TRP B 2 452 ? 80.496  104.858 94.744  1.00 513.59 ? 452 TRP B N   1 
ATOM   6705  C CA  . TRP B 2 452 ? 79.613  105.100 95.885  1.00 481.21 ? 452 TRP B CA  1 
ATOM   6706  C C   . TRP B 2 452 ? 80.343  104.980 97.233  1.00 444.97 ? 452 TRP B C   1 
ATOM   6707  O O   . TRP B 2 452 ? 80.083  105.780 98.134  1.00 351.64 ? 452 TRP B O   1 
ATOM   6708  C CB  . TRP B 2 452 ? 78.404  104.151 95.802  1.00 489.71 ? 452 TRP B CB  1 
ATOM   6709  C CG  . TRP B 2 452 ? 77.569  104.049 97.054  1.00 457.80 ? 452 TRP B CG  1 
ATOM   6710  C CD1 . TRP B 2 452 ? 76.823  105.037 97.626  1.00 420.29 ? 452 TRP B CD1 1 
ATOM   6711  C CD2 . TRP B 2 452 ? 77.401  102.877 97.890  1.00 452.00 ? 452 TRP B CD2 1 
ATOM   6712  N NE1 . TRP B 2 452 ? 76.201  104.569 98.753  1.00 428.05 ? 452 TRP B NE1 1 
ATOM   6713  C CE2 . TRP B 2 452 ? 76.533  103.250 98.944  1.00 439.03 ? 452 TRP B CE2 1 
ATOM   6714  C CE3 . TRP B 2 452 ? 77.890  101.559 97.856  1.00 452.30 ? 452 TRP B CE3 1 
ATOM   6715  C CZ2 . TRP B 2 452 ? 76.152  102.351 99.947  1.00 418.88 ? 452 TRP B CZ2 1 
ATOM   6716  C CZ3 . TRP B 2 452 ? 77.512  100.673 98.848  1.00 413.06 ? 452 TRP B CZ3 1 
ATOM   6717  C CH2 . TRP B 2 452 ? 76.655  101.067 99.879  1.00 394.94 ? 452 TRP B CH2 1 
ATOM   6718  N N   . LYS B 2 453 ? 81.251  103.995 97.365  1.00 456.93 ? 453 LYS B N   1 
ATOM   6719  C CA  . LYS B 2 453 ? 82.052  103.812 98.573  1.00 433.82 ? 453 LYS B CA  1 
ATOM   6720  C C   . LYS B 2 453 ? 83.222  104.804 98.700  1.00 441.74 ? 453 LYS B C   1 
ATOM   6721  O O   . LYS B 2 453 ? 83.715  104.958 99.819  1.00 354.96 ? 453 LYS B O   1 
ATOM   6722  C CB  . LYS B 2 453 ? 82.576  102.369 98.642  1.00 386.46 ? 453 LYS B CB  1 
ATOM   6723  C CG  . LYS B 2 453 ? 81.514  101.289 98.837  1.00 368.82 ? 453 LYS B CG  1 
ATOM   6724  C CD  . LYS B 2 453 ? 80.663  101.424 100.097 1.00 420.48 ? 453 LYS B CD  1 
ATOM   6725  C CE  . LYS B 2 453 ? 81.474  101.472 101.379 1.00 443.36 ? 453 LYS B CE  1 
ATOM   6726  N NZ  . LYS B 2 453 ? 80.632  101.290 102.587 1.00 453.74 ? 453 LYS B NZ  1 
ATOM   6727  N N   . THR B 2 454 ? 83.675  105.468 97.608  1.00 483.69 ? 454 THR B N   1 
ATOM   6728  C CA  . THR B 2 454 ? 84.852  106.348 97.639  1.00 448.19 ? 454 THR B CA  1 
ATOM   6729  C C   . THR B 2 454 ? 84.646  107.677 96.878  1.00 460.43 ? 454 THR B C   1 
ATOM   6730  O O   . THR B 2 454 ? 85.487  108.039 96.044  1.00 395.76 ? 454 THR B O   1 
ATOM   6731  C CB  . THR B 2 454 ? 86.097  105.586 97.130  1.00 382.58 ? 454 THR B CB  1 
ATOM   6732  O OG1 . THR B 2 454 ? 85.912  105.160 95.777  1.00 358.57 ? 454 THR B OG1 1 
ATOM   6733  C CG2 . THR B 2 454 ? 86.448  104.379 97.975  1.00 346.19 ? 454 THR B CG2 1 
ATOM   6734  N N   . PRO B 2 455 ? 83.572  108.486 97.127  1.00 478.93 ? 455 PRO B N   1 
ATOM   6735  C CA  . PRO B 2 455 ? 83.354  109.742 96.390  1.00 511.56 ? 455 PRO B CA  1 
ATOM   6736  C C   . PRO B 2 455 ? 84.476  110.786 96.467  1.00 585.34 ? 455 PRO B C   1 
ATOM   6737  O O   . PRO B 2 455 ? 84.672  111.521 95.504  1.00 617.24 ? 455 PRO B O   1 
ATOM   6738  C CB  . PRO B 2 455 ? 82.079  110.338 97.026  1.00 464.20 ? 455 PRO B CB  1 
ATOM   6739  C CG  . PRO B 2 455 ? 81.375  109.148 97.618  1.00 436.62 ? 455 PRO B CG  1 
ATOM   6740  C CD  . PRO B 2 455 ? 82.502  108.271 98.119  1.00 447.38 ? 455 PRO B CD  1 
ATOM   6741  N N   . VAL B 2 456 ? 85.209  110.841 97.595  1.00 610.70 ? 456 VAL B N   1 
ATOM   6742  C CA  . VAL B 2 456 ? 86.264  111.829 97.819  1.00 588.87 ? 456 VAL B CA  1 
ATOM   6743  C C   . VAL B 2 456 ? 87.434  111.569 96.860  1.00 535.50 ? 456 VAL B C   1 
ATOM   6744  O O   . VAL B 2 456 ? 87.948  112.509 96.252  1.00 471.77 ? 456 VAL B O   1 
ATOM   6745  C CB  . VAL B 2 456 ? 86.716  111.850 99.300  1.00 598.32 ? 456 VAL B CB  1 
ATOM   6746  C CG1 . VAL B 2 456 ? 87.870  112.818 99.552  1.00 594.53 ? 456 VAL B CG1 1 
ATOM   6747  C CG2 . VAL B 2 456 ? 85.558  112.163 100.244 1.00 583.66 ? 456 VAL B CG2 1 
ATOM   6748  N N   . GLU B 2 457 ? 87.834  110.294 96.721  1.00 513.46 ? 457 GLU B N   1 
ATOM   6749  C CA  . GLU B 2 457 ? 88.911  109.872 95.832  1.00 486.42 ? 457 GLU B CA  1 
ATOM   6750  C C   . GLU B 2 457 ? 88.472  109.929 94.363  1.00 478.81 ? 457 GLU B C   1 
ATOM   6751  O O   . GLU B 2 457 ? 89.230  110.407 93.512  1.00 500.30 ? 457 GLU B O   1 
ATOM   6752  C CB  . GLU B 2 457 ? 89.375  108.458 96.201  1.00 483.50 ? 457 GLU B CB  1 
ATOM   6753  C CG  . GLU B 2 457 ? 90.027  108.348 97.577  1.00 476.27 ? 457 GLU B CG  1 
ATOM   6754  C CD  . GLU B 2 457 ? 89.119  108.328 98.800  1.00 475.69 ? 457 GLU B CD  1 
ATOM   6755  O OE1 . GLU B 2 457 ? 87.881  108.270 98.642  1.00 494.59 ? 457 GLU B OE1 1 
ATOM   6756  O OE2 . GLU B 2 457 ? 89.655  108.375 99.918  1.00 453.67 ? 457 GLU B OE2 1 
ATOM   6757  N N   . CYS B 2 458 ? 87.257  109.442 94.057  1.00 447.26 ? 458 CYS B N   1 
ATOM   6758  C CA  . CYS B 2 458 ? 86.767  109.394 92.682  1.00 433.44 ? 458 CYS B CA  1 
ATOM   6759  C C   . CYS B 2 458 ? 86.543  110.799 92.107  1.00 411.17 ? 458 CYS B C   1 
ATOM   6760  O O   . CYS B 2 458 ? 86.775  111.007 90.915  1.00 318.77 ? 458 CYS B O   1 
ATOM   6761  C CB  . CYS B 2 458 ? 85.502  108.543 92.591  1.00 443.13 ? 458 CYS B CB  1 
ATOM   6762  S SG  . CYS B 2 458 ? 85.819  106.811 93.026  1.00 470.61 ? 458 CYS B SG  1 
ATOM   6763  N N   . GLY B 2 459 ? 86.109  111.751 92.953  1.00 488.48 ? 459 GLY B N   1 
ATOM   6764  C CA  . GLY B 2 459 ? 85.921  113.148 92.582  1.00 547.27 ? 459 GLY B CA  1 
ATOM   6765  C C   . GLY B 2 459 ? 87.184  113.807 92.030  1.00 580.14 ? 459 GLY B C   1 
ATOM   6766  O O   . GLY B 2 459 ? 87.138  114.379 90.939  1.00 602.45 ? 459 GLY B O   1 
ATOM   6767  N N   . ILE B 2 460 ? 88.301  113.718 92.778  1.00 567.86 ? 460 ILE B N   1 
ATOM   6768  C CA  . ILE B 2 460 ? 89.590  114.226 92.304  1.00 514.41 ? 460 ILE B CA  1 
ATOM   6769  C C   . ILE B 2 460 ? 90.026  113.436 91.058  1.00 414.19 ? 460 ILE B C   1 
ATOM   6770  O O   . ILE B 2 460 ? 90.622  114.032 90.161  1.00 308.99 ? 460 ILE B O   1 
ATOM   6771  C CB  . ILE B 2 460 ? 90.665  114.297 93.430  1.00 514.20 ? 460 ILE B CB  1 
ATOM   6772  C CG1 . ILE B 2 460 ? 91.955  115.000 92.975  1.00 449.95 ? 460 ILE B CG1 1 
ATOM   6773  C CG2 . ILE B 2 460 ? 90.984  112.944 94.058  1.00 525.78 ? 460 ILE B CG2 1 
ATOM   6774  C CD1 . ILE B 2 460 ? 91.800  116.479 92.693  1.00 420.09 ? 460 ILE B CD1 1 
ATOM   6775  N N   . GLY B 2 461 ? 89.714  112.128 90.984  1.00 402.93 ? 461 GLY B N   1 
ATOM   6776  C CA  . GLY B 2 461 ? 89.906  111.313 89.786  1.00 412.27 ? 461 GLY B CA  1 
ATOM   6777  C C   . GLY B 2 461 ? 89.326  111.930 88.507  1.00 362.70 ? 461 GLY B C   1 
ATOM   6778  O O   . GLY B 2 461 ? 90.008  111.968 87.482  1.00 377.23 ? 461 GLY B O   1 
ATOM   6779  N N   . PHE B 2 462 ? 88.080  112.421 88.563  1.00 342.18 ? 462 PHE B N   1 
ATOM   6780  C CA  . PHE B 2 462 ? 87.456  113.073 87.412  1.00 387.22 ? 462 PHE B CA  1 
ATOM   6781  C C   . PHE B 2 462 ? 88.217  114.331 86.956  1.00 407.86 ? 462 PHE B C   1 
ATOM   6782  O O   . PHE B 2 462 ? 88.109  114.675 85.779  1.00 412.53 ? 462 PHE B O   1 
ATOM   6783  C CB  . PHE B 2 462 ? 85.970  113.361 87.677  1.00 437.33 ? 462 PHE B CB  1 
ATOM   6784  C CG  . PHE B 2 462 ? 85.042  112.294 87.148  1.00 479.50 ? 462 PHE B CG  1 
ATOM   6785  C CD1 . PHE B 2 462 ? 84.649  112.299 85.814  1.00 496.05 ? 462 PHE B CD1 1 
ATOM   6786  C CD2 . PHE B 2 462 ? 84.567  111.278 87.969  1.00 491.19 ? 462 PHE B CD2 1 
ATOM   6787  C CE1 . PHE B 2 462 ? 83.799  111.318 85.316  1.00 513.25 ? 462 PHE B CE1 1 
ATOM   6788  C CE2 . PHE B 2 462 ? 83.717  110.296 87.472  1.00 492.48 ? 462 PHE B CE2 1 
ATOM   6789  C CZ  . PHE B 2 462 ? 83.334  110.318 86.146  1.00 501.46 ? 462 PHE B CZ  1 
ATOM   6790  N N   . THR B 2 463 ? 88.988  115.010 87.829  1.00 439.28 ? 463 THR B N   1 
ATOM   6791  C CA  . THR B 2 463 ? 89.784  116.167 87.409  1.00 444.94 ? 463 THR B CA  1 
ATOM   6792  C C   . THR B 2 463 ? 90.959  115.756 86.508  1.00 359.69 ? 463 THR B C   1 
ATOM   6793  O O   . THR B 2 463 ? 91.364  116.545 85.656  1.00 286.84 ? 463 THR B O   1 
ATOM   6794  C CB  . THR B 2 463 ? 90.297  117.022 88.585  1.00 527.88 ? 463 THR B CB  1 
ATOM   6795  O OG1 . THR B 2 463 ? 91.391  116.379 89.245  1.00 542.14 ? 463 THR B OG1 1 
ATOM   6796  C CG2 . THR B 2 463 ? 89.215  117.357 89.591  1.00 561.73 ? 463 THR B CG2 1 
ATOM   6797  N N   . ILE B 2 464 ? 91.503  114.541 86.688  1.00 356.32 ? 464 ILE B N   1 
ATOM   6798  C CA  . ILE B 2 464 ? 92.507  113.991 85.781  1.00 391.26 ? 464 ILE B CA  1 
ATOM   6799  C C   . ILE B 2 464 ? 91.881  113.825 84.391  1.00 376.33 ? 464 ILE B C   1 
ATOM   6800  O O   . ILE B 2 464 ? 92.497  114.223 83.406  1.00 321.46 ? 464 ILE B O   1 
ATOM   6801  C CB  . ILE B 2 464 ? 93.112  112.672 86.323  1.00 481.02 ? 464 ILE B CB  1 
ATOM   6802  C CG1 . ILE B 2 464 ? 93.762  112.844 87.706  1.00 458.22 ? 464 ILE B CG1 1 
ATOM   6803  C CG2 . ILE B 2 464 ? 94.093  112.056 85.327  1.00 542.71 ? 464 ILE B CG2 1 
ATOM   6804  C CD1 . ILE B 2 464 ? 94.890  113.869 87.785  1.00 405.85 ? 464 ILE B CD1 1 
ATOM   6805  N N   . ILE B 2 465 ? 90.663  113.257 84.324  1.00 396.41 ? 465 ILE B N   1 
ATOM   6806  C CA  . ILE B 2 465 ? 89.929  113.041 83.076  1.00 386.30 ? 465 ILE B CA  1 
ATOM   6807  C C   . ILE B 2 465 ? 89.731  114.387 82.373  1.00 369.16 ? 465 ILE B C   1 
ATOM   6808  O O   . ILE B 2 465 ? 90.154  114.556 81.227  1.00 250.85 ? 465 ILE B O   1 
ATOM   6809  C CB  . ILE B 2 465 ? 88.577  112.314 83.312  1.00 371.55 ? 465 ILE B CB  1 
ATOM   6810  C CG1 . ILE B 2 465 ? 88.767  110.944 83.979  1.00 424.15 ? 465 ILE B CG1 1 
ATOM   6811  C CG2 . ILE B 2 465 ? 87.766  112.201 82.019  1.00 350.89 ? 465 ILE B CG2 1 
ATOM   6812  C CD1 . ILE B 2 465 ? 87.487  110.203 84.312  1.00 456.68 ? 465 ILE B CD1 1 
ATOM   6813  N N   . LEU B 2 466 ? 89.096  115.333 83.085  1.00 422.40 ? 466 LEU B N   1 
ATOM   6814  C CA  . LEU B 2 466 ? 88.695  116.622 82.534  1.00 436.57 ? 466 LEU B CA  1 
ATOM   6815  C C   . LEU B 2 466 ? 89.899  117.533 82.238  1.00 348.77 ? 466 LEU B C   1 
ATOM   6816  O O   . LEU B 2 466 ? 89.736  118.481 81.477  1.00 284.63 ? 466 LEU B O   1 
ATOM   6817  C CB  . LEU B 2 466 ? 87.703  117.288 83.502  1.00 493.53 ? 466 LEU B CB  1 
ATOM   6818  C CG  . LEU B 2 466 ? 86.352  116.585 83.670  1.00 511.15 ? 466 LEU B CG  1 
ATOM   6819  C CD1 . LEU B 2 466 ? 85.587  117.154 84.856  1.00 537.99 ? 466 LEU B CD1 1 
ATOM   6820  C CD2 . LEU B 2 466 ? 85.506  116.688 82.409  1.00 499.79 ? 466 LEU B CD2 1 
ATOM   6821  N N   . SER B 2 467 ? 91.098  117.262 82.796  1.00 321.90 ? 467 SER B N   1 
ATOM   6822  C CA  . SER B 2 467 ? 92.320  117.984 82.438  1.00 346.55 ? 467 SER B CA  1 
ATOM   6823  C C   . SER B 2 467 ? 92.673  117.887 80.948  1.00 349.36 ? 467 SER B C   1 
ATOM   6824  O O   . SER B 2 467 ? 93.483  118.679 80.473  1.00 346.81 ? 467 SER B O   1 
ATOM   6825  C CB  . SER B 2 467 ? 93.508  117.521 83.258  1.00 356.39 ? 467 SER B CB  1 
ATOM   6826  O OG  . SER B 2 467 ? 93.999  116.270 82.795  1.00 382.74 ? 467 SER B OG  1 
ATOM   6827  N N   . GLY B 2 468 ? 92.098  116.916 80.222  1.00 347.48 ? 468 GLY B N   1 
ATOM   6828  C CA  . GLY B 2 468 ? 92.319  116.755 78.795  1.00 361.73 ? 468 GLY B CA  1 
ATOM   6829  C C   . GLY B 2 468 ? 91.681  117.831 77.912  1.00 331.53 ? 468 GLY B C   1 
ATOM   6830  O O   . GLY B 2 468 ? 92.211  118.102 76.840  1.00 287.91 ? 468 GLY B O   1 
ATOM   6831  N N   . LEU B 2 469 ? 90.563  118.443 78.335  1.00 315.57 ? 469 LEU B N   1 
ATOM   6832  C CA  . LEU B 2 469 ? 89.807  119.323 77.451  1.00 289.66 ? 469 LEU B CA  1 
ATOM   6833  C C   . LEU B 2 469 ? 90.626  120.567 77.079  1.00 301.22 ? 469 LEU B C   1 
ATOM   6834  O O   . LEU B 2 469 ? 90.634  120.921 75.902  1.00 279.24 ? 469 LEU B O   1 
ATOM   6835  C CB  . LEU B 2 469 ? 88.451  119.682 78.078  1.00 320.39 ? 469 LEU B CB  1 
ATOM   6836  C CG  . LEU B 2 469 ? 87.381  118.591 77.969  1.00 360.29 ? 469 LEU B CG  1 
ATOM   6837  C CD1 . LEU B 2 469 ? 87.452  117.635 79.148  1.00 402.55 ? 469 LEU B CD1 1 
ATOM   6838  C CD2 . LEU B 2 469 ? 85.981  119.182 77.857  1.00 368.83 ? 469 LEU B CD2 1 
ATOM   6839  N N   . PRO B 2 470 ? 91.328  121.273 78.009  1.00 341.79 ? 470 PRO B N   1 
ATOM   6840  C CA  . PRO B 2 470 ? 92.295  122.317 77.634  1.00 384.45 ? 470 PRO B CA  1 
ATOM   6841  C C   . PRO B 2 470 ? 93.283  121.945 76.527  1.00 344.22 ? 470 PRO B C   1 
ATOM   6842  O O   . PRO B 2 470 ? 93.438  122.707 75.572  1.00 295.59 ? 470 PRO B O   1 
ATOM   6843  C CB  . PRO B 2 470 ? 93.042  122.567 78.957  1.00 380.06 ? 470 PRO B CB  1 
ATOM   6844  C CG  . PRO B 2 470 ? 91.962  122.375 79.988  1.00 353.07 ? 470 PRO B CG  1 
ATOM   6845  C CD  . PRO B 2 470 ? 91.223  121.157 79.473  1.00 329.43 ? 470 PRO B CD  1 
ATOM   6846  N N   . VAL B 2 471 ? 93.920  120.775 76.656  1.00 324.85 ? 471 VAL B N   1 
ATOM   6847  C CA  . VAL B 2 471 ? 94.942  120.326 75.718  1.00 316.30 ? 471 VAL B CA  1 
ATOM   6848  C C   . VAL B 2 471 ? 94.284  119.920 74.395  1.00 312.01 ? 471 VAL B C   1 
ATOM   6849  O O   . VAL B 2 471 ? 94.835  120.210 73.331  1.00 358.18 ? 471 VAL B O   1 
ATOM   6850  C CB  . VAL B 2 471 ? 95.795  119.188 76.321  1.00 347.82 ? 471 VAL B CB  1 
ATOM   6851  C CG1 . VAL B 2 471 ? 96.880  118.699 75.366  1.00 364.33 ? 471 VAL B CG1 1 
ATOM   6852  C CG2 . VAL B 2 471 ? 96.417  119.590 77.657  1.00 383.79 ? 471 VAL B CG2 1 
ATOM   6853  N N   . TYR B 2 472 ? 93.117  119.258 74.464  1.00 309.04 ? 472 TYR B N   1 
ATOM   6854  C CA  . TYR B 2 472 ? 92.339  118.874 73.292  1.00 307.74 ? 472 TYR B CA  1 
ATOM   6855  C C   . TYR B 2 472 ? 91.989  120.087 72.430  1.00 276.97 ? 472 TYR B C   1 
ATOM   6856  O O   . TYR B 2 472 ? 92.289  120.109 71.237  1.00 173.15 ? 472 TYR B O   1 
ATOM   6857  C CB  . TYR B 2 472 ? 91.059  118.155 73.725  1.00 272.04 ? 472 TYR B CB  1 
ATOM   6858  C CG  . TYR B 2 472 ? 90.174  117.764 72.556  1.00 237.53 ? 472 TYR B CG  1 
ATOM   6859  C CD1 . TYR B 2 472 ? 90.499  116.680 71.744  1.00 273.22 ? 472 TYR B CD1 1 
ATOM   6860  C CD2 . TYR B 2 472 ? 89.030  118.483 72.250  1.00 249.76 ? 472 TYR B CD2 1 
ATOM   6861  C CE1 . TYR B 2 472 ? 89.708  116.311 70.667  1.00 205.00 ? 472 TYR B CE1 1 
ATOM   6862  C CE2 . TYR B 2 472 ? 88.226  118.122 71.176  1.00 273.92 ? 472 TYR B CE2 1 
ATOM   6863  C CZ  . TYR B 2 472 ? 88.566  117.032 70.387  1.00 222.00 ? 472 TYR B CZ  1 
ATOM   6864  O OH  . TYR B 2 472 ? 87.799  116.658 69.326  1.00 273.14 ? 472 TYR B OH  1 
ATOM   6865  N N   . PHE B 2 473 ? 91.356  121.095 73.036  1.00 295.64 ? 473 PHE B N   1 
ATOM   6866  C CA  . PHE B 2 473 ? 90.977  122.287 72.292  1.00 319.01 ? 473 PHE B CA  1 
ATOM   6867  C C   . PHE B 2 473 ? 92.227  122.978 71.731  1.00 320.99 ? 473 PHE B C   1 
ATOM   6868  O O   . PHE B 2 473 ? 92.236  123.305 70.545  1.00 347.36 ? 473 PHE B O   1 
ATOM   6869  C CB  . PHE B 2 473 ? 90.076  123.182 73.152  1.00 333.98 ? 473 PHE B CB  1 
ATOM   6870  C CG  . PHE B 2 473 ? 88.668  122.663 73.352  1.00 380.83 ? 473 PHE B CG  1 
ATOM   6871  C CD1 . PHE B 2 473 ? 87.899  122.206 72.280  1.00 407.91 ? 473 PHE B CD1 1 
ATOM   6872  C CD2 . PHE B 2 473 ? 88.093  122.632 74.618  1.00 411.09 ? 473 PHE B CD2 1 
ATOM   6873  C CE1 . PHE B 2 473 ? 86.606  121.731 72.469  1.00 396.56 ? 473 PHE B CE1 1 
ATOM   6874  C CE2 . PHE B 2 473 ? 86.797  122.160 74.805  1.00 403.23 ? 473 PHE B CE2 1 
ATOM   6875  C CZ  . PHE B 2 473 ? 86.054  121.711 73.733  1.00 376.25 ? 473 PHE B CZ  1 
ATOM   6876  N N   . PHE B 2 474 ? 93.271  123.174 72.555  1.00 301.99 ? 474 PHE B N   1 
ATOM   6877  C CA  . PHE B 2 474 ? 94.484  123.871 72.129  1.00 323.64 ? 474 PHE B CA  1 
ATOM   6878  C C   . PHE B 2 474 ? 95.182  123.185 70.942  1.00 301.59 ? 474 PHE B C   1 
ATOM   6879  O O   . PHE B 2 474 ? 95.612  123.875 70.010  1.00 363.06 ? 474 PHE B O   1 
ATOM   6880  C CB  . PHE B 2 474 ? 95.456  124.044 73.303  1.00 339.15 ? 474 PHE B CB  1 
ATOM   6881  C CG  . PHE B 2 474 ? 96.688  124.850 72.962  1.00 375.93 ? 474 PHE B CG  1 
ATOM   6882  C CD1 . PHE B 2 474 ? 97.791  124.240 72.368  1.00 365.38 ? 474 PHE B CD1 1 
ATOM   6883  C CD2 . PHE B 2 474 ? 96.741  126.221 73.213  1.00 400.78 ? 474 PHE B CD2 1 
ATOM   6884  C CE1 . PHE B 2 474 ? 98.923  124.977 72.046  1.00 379.16 ? 474 PHE B CE1 1 
ATOM   6885  C CE2 . PHE B 2 474 ? 97.879  126.954 72.892  1.00 385.12 ? 474 PHE B CE2 1 
ATOM   6886  C CZ  . PHE B 2 474 ? 98.966  126.333 72.308  1.00 381.85 ? 474 PHE B CZ  1 
ATOM   6887  N N   . GLY B 2 475 ? 95.295  121.849 70.976  1.00 270.23 ? 475 GLY B N   1 
ATOM   6888  C CA  . GLY B 2 475 ? 96.064  121.089 69.995  1.00 279.57 ? 475 GLY B CA  1 
ATOM   6889  C C   . GLY B 2 475 ? 95.244  120.546 68.818  1.00 288.97 ? 475 GLY B C   1 
ATOM   6890  O O   . GLY B 2 475 ? 95.762  120.518 67.699  1.00 275.84 ? 475 GLY B O   1 
ATOM   6891  N N   . VAL B 2 476 ? 93.987  120.114 69.067  1.00 253.87 ? 476 VAL B N   1 
ATOM   6892  C CA  . VAL B 2 476 ? 93.215  119.307 68.120  1.00 303.09 ? 476 VAL B CA  1 
ATOM   6893  C C   . VAL B 2 476 ? 92.197  120.162 67.354  1.00 359.80 ? 476 VAL B C   1 
ATOM   6894  O O   . VAL B 2 476 ? 92.076  119.991 66.141  1.00 424.00 ? 476 VAL B O   1 
ATOM   6895  C CB  . VAL B 2 476 ? 92.516  118.105 68.801  1.00 234.44 ? 476 VAL B CB  1 
ATOM   6896  C CG1 . VAL B 2 476 ? 91.774  117.221 67.807  1.00 258.78 ? 476 VAL B CG1 1 
ATOM   6897  C CG2 . VAL B 2 476 ? 93.498  117.255 69.595  1.00 246.40 ? 476 VAL B CG2 1 
ATOM   6898  N N   . TRP B 2 477 ? 91.460  121.057 68.034  1.00 334.35 ? 477 TRP B N   1 
ATOM   6899  C CA  . TRP B 2 477 ? 90.149  121.480 67.544  1.00 360.42 ? 477 TRP B CA  1 
ATOM   6900  C C   . TRP B 2 477 ? 89.989  123.003 67.478  1.00 324.10 ? 477 TRP B C   1 
ATOM   6901  O O   . TRP B 2 477 ? 89.667  123.523 66.412  1.00 319.04 ? 477 TRP B O   1 
ATOM   6902  C CB  . TRP B 2 477 ? 89.065  120.837 68.422  1.00 415.83 ? 477 TRP B CB  1 
ATOM   6903  C CG  . TRP B 2 477 ? 87.654  120.974 67.899  1.00 417.15 ? 477 TRP B CG  1 
ATOM   6904  C CD1 . TRP B 2 477 ? 86.979  120.046 67.159  1.00 393.41 ? 477 TRP B CD1 1 
ATOM   6905  C CD2 . TRP B 2 477 ? 86.738  122.083 68.081  1.00 395.25 ? 477 TRP B CD2 1 
ATOM   6906  N NE1 . TRP B 2 477 ? 85.719  120.491 66.861  1.00 361.90 ? 477 TRP B NE1 1 
ATOM   6907  C CE2 . TRP B 2 477 ? 85.538  121.734 67.411  1.00 373.98 ? 477 TRP B CE2 1 
ATOM   6908  C CE3 . TRP B 2 477 ? 86.802  123.328 68.734  1.00 383.54 ? 477 TRP B CE3 1 
ATOM   6909  C CZ2 . TRP B 2 477 ? 84.429  122.583 67.379  1.00 392.44 ? 477 TRP B CZ2 1 
ATOM   6910  C CZ3 . TRP B 2 477 ? 85.705  124.165 68.702  1.00 383.01 ? 477 TRP B CZ3 1 
ATOM   6911  C CH2 . TRP B 2 477 ? 84.534  123.794 68.032  1.00 408.18 ? 477 TRP B CH2 1 
ATOM   6912  N N   . TRP B 2 478 ? 90.194  123.699 68.608  1.00 345.43 ? 478 TRP B N   1 
ATOM   6913  C CA  . TRP B 2 478 ? 90.065  125.153 68.712  1.00 407.33 ? 478 TRP B CA  1 
ATOM   6914  C C   . TRP B 2 478 ? 91.261  125.823 68.020  1.00 409.05 ? 478 TRP B C   1 
ATOM   6915  O O   . TRP B 2 478 ? 91.104  126.869 67.380  1.00 372.58 ? 478 TRP B O   1 
ATOM   6916  C CB  . TRP B 2 478 ? 89.930  125.529 70.204  1.00 484.04 ? 478 TRP B CB  1 
ATOM   6917  C CG  . TRP B 2 478 ? 89.414  126.903 70.582  1.00 509.45 ? 478 TRP B CG  1 
ATOM   6918  C CD1 . TRP B 2 478 ? 89.792  128.123 70.093  1.00 459.98 ? 478 TRP B CD1 1 
ATOM   6919  C CD2 . TRP B 2 478 ? 88.406  127.178 71.590  1.00 524.86 ? 478 TRP B CD2 1 
ATOM   6920  N NE1 . TRP B 2 478 ? 89.091  129.127 70.709  1.00 448.92 ? 478 TRP B NE1 1 
ATOM   6921  C CE2 . TRP B 2 478 ? 88.235  128.583 71.633  1.00 492.18 ? 478 TRP B CE2 1 
ATOM   6922  C CE3 . TRP B 2 478 ? 87.632  126.380 72.454  1.00 491.83 ? 478 TRP B CE3 1 
ATOM   6923  C CZ2 . TRP B 2 478 ? 87.326  129.193 72.504  1.00 467.35 ? 478 TRP B CZ2 1 
ATOM   6924  C CZ3 . TRP B 2 478 ? 86.735  126.985 73.314  1.00 413.64 ? 478 TRP B CZ3 1 
ATOM   6925  C CH2 . TRP B 2 478 ? 86.587  128.375 73.338  1.00 422.16 ? 478 TRP B CH2 1 
ATOM   6926  N N   . LYS B 2 479 ? 92.448  125.204 68.179  1.00 447.30 ? 479 LYS B N   1 
ATOM   6927  C CA  . LYS B 2 479 ? 93.636  125.404 67.348  1.00 442.49 ? 479 LYS B CA  1 
ATOM   6928  C C   . LYS B 2 479 ? 94.051  126.881 67.285  1.00 400.66 ? 479 LYS B C   1 
ATOM   6929  O O   . LYS B 2 479 ? 93.992  127.506 66.230  1.00 344.85 ? 479 LYS B O   1 
ATOM   6930  C CB  . LYS B 2 479 ? 93.389  124.804 65.956  1.00 414.83 ? 479 LYS B CB  1 
ATOM   6931  C CG  . LYS B 2 479 ? 94.617  124.593 65.082  1.00 406.75 ? 479 LYS B CG  1 
ATOM   6932  C CD  . LYS B 2 479 ? 94.325  123.762 63.848  1.00 375.07 ? 479 LYS B CD  1 
ATOM   6933  C CE  . LYS B 2 479 ? 93.455  124.469 62.830  1.00 349.09 ? 479 LYS B CE  1 
ATOM   6934  N NZ  . LYS B 2 479 ? 93.147  123.575 61.689  1.00 315.99 ? 479 LYS B NZ  1 
ATOM   6935  N N   . ASN B 2 480 ? 94.491  127.442 68.421  1.00 425.40 ? 480 ASN B N   1 
ATOM   6936  C CA  . ASN B 2 480 ? 95.133  128.754 68.399  1.00 396.96 ? 480 ASN B CA  1 
ATOM   6937  C C   . ASN B 2 480 ? 96.429  128.607 67.589  1.00 346.98 ? 480 ASN B C   1 
ATOM   6938  O O   . ASN B 2 480 ? 97.215  127.692 67.842  1.00 276.72 ? 480 ASN B O   1 
ATOM   6939  C CB  . ASN B 2 480 ? 95.380  129.345 69.795  1.00 404.63 ? 480 ASN B CB  1 
ATOM   6940  C CG  . ASN B 2 480 ? 94.156  129.369 70.694  1.00 334.64 ? 480 ASN B CG  1 
ATOM   6941  O OD1 . ASN B 2 480 ? 93.822  128.344 71.288  1.00 349.57 ? 480 ASN B OD1 1 
ATOM   6942  N ND2 . ASN B 2 480 ? 93.497  130.512 70.819  1.00 252.36 ? 480 ASN B ND2 1 
ATOM   6943  N N   . LYS B 2 481 ? 96.640  129.502 66.606  1.00 353.61 ? 481 LYS B N   1 
ATOM   6944  C CA  . LYS B 2 481 ? 97.587  129.260 65.518  1.00 387.11 ? 481 LYS B CA  1 
ATOM   6945  C C   . LYS B 2 481 ? 98.298  130.547 65.051  1.00 414.09 ? 481 LYS B C   1 
ATOM   6946  O O   . LYS B 2 481 ? 98.212  130.900 63.871  1.00 429.81 ? 481 LYS B O   1 
ATOM   6947  C CB  . LYS B 2 481 ? 96.829  128.520 64.400  1.00 386.22 ? 481 LYS B CB  1 
ATOM   6948  C CG  . LYS B 2 481 ? 95.555  129.174 63.859  1.00 402.36 ? 481 LYS B CG  1 
ATOM   6949  C CD  . LYS B 2 481 ? 94.707  128.238 63.004  1.00 415.55 ? 481 LYS B CD  1 
ATOM   6950  C CE  . LYS B 2 481 ? 93.429  128.878 62.495  1.00 388.45 ? 481 LYS B CE  1 
ATOM   6951  N NZ  . LYS B 2 481 ? 92.410  129.051 63.562  1.00 329.62 ? 481 LYS B NZ  1 
ATOM   6952  N N   . PRO B 2 482 ? 99.053  131.291 65.915  1.00 375.06 ? 482 PRO B N   1 
ATOM   6953  C CA  . PRO B 2 482 ? 99.996  132.303 65.425  1.00 348.77 ? 482 PRO B CA  1 
ATOM   6954  C C   . PRO B 2 482 ? 101.063 131.608 64.576  1.00 417.34 ? 482 PRO B C   1 
ATOM   6955  O O   . PRO B 2 482 ? 101.539 130.549 64.964  1.00 441.96 ? 482 PRO B O   1 
ATOM   6956  C CB  . PRO B 2 482 ? 100.625 132.936 66.681  1.00 274.99 ? 482 PRO B CB  1 
ATOM   6957  C CG  . PRO B 2 482 ? 99.739  132.508 67.834  1.00 285.10 ? 482 PRO B CG  1 
ATOM   6958  C CD  . PRO B 2 482 ? 99.075  131.217 67.389  1.00 334.67 ? 482 PRO B CD  1 
ATOM   6959  N N   . LYS B 2 483 ? 101.443 132.184 63.427  1.00 441.14 ? 483 LYS B N   1 
ATOM   6960  C CA  . LYS B 2 483 ? 102.323 131.487 62.490  1.00 432.69 ? 483 LYS B CA  1 
ATOM   6961  C C   . LYS B 2 483 ? 103.730 131.264 63.070  1.00 375.60 ? 483 LYS B C   1 
ATOM   6962  O O   . LYS B 2 483 ? 104.418 130.352 62.609  1.00 321.84 ? 483 LYS B O   1 
ATOM   6963  C CB  . LYS B 2 483 ? 102.358 132.214 61.138  1.00 478.60 ? 483 LYS B CB  1 
ATOM   6964  C CG  . LYS B 2 483 ? 101.020 132.315 60.409  1.00 503.76 ? 483 LYS B CG  1 
ATOM   6965  C CD  . LYS B 2 483 ? 100.331 130.979 60.147  1.00 508.13 ? 483 LYS B CD  1 
ATOM   6966  C CE  . LYS B 2 483 ? 99.102  131.079 59.266  1.00 509.01 ? 483 LYS B CE  1 
ATOM   6967  N NZ  . LYS B 2 483 ? 99.447  131.309 57.842  1.00 515.34 ? 483 LYS B NZ  1 
ATOM   6968  N N   . TRP B 2 484 ? 104.154 132.061 64.071  1.00 378.68 ? 484 TRP B N   1 
ATOM   6969  C CA  . TRP B 2 484 ? 105.387 131.796 64.814  1.00 421.82 ? 484 TRP B CA  1 
ATOM   6970  C C   . TRP B 2 484 ? 105.317 130.491 65.621  1.00 438.57 ? 484 TRP B C   1 
ATOM   6971  O O   . TRP B 2 484 ? 106.335 129.806 65.744  1.00 453.14 ? 484 TRP B O   1 
ATOM   6972  C CB  . TRP B 2 484 ? 105.767 132.991 65.713  1.00 422.58 ? 484 TRP B CB  1 
ATOM   6973  C CG  . TRP B 2 484 ? 104.800 133.341 66.819  1.00 442.38 ? 484 TRP B CG  1 
ATOM   6974  C CD1 . TRP B 2 484 ? 103.893 134.359 66.778  1.00 475.33 ? 484 TRP B CD1 1 
ATOM   6975  C CD2 . TRP B 2 484 ? 104.640 132.711 68.116  1.00 426.39 ? 484 TRP B CD2 1 
ATOM   6976  N NE1 . TRP B 2 484 ? 103.175 134.409 67.943  1.00 470.50 ? 484 TRP B NE1 1 
ATOM   6977  C CE2 . TRP B 2 484 ? 103.605 133.415 68.783  1.00 451.68 ? 484 TRP B CE2 1 
ATOM   6978  C CE3 . TRP B 2 484 ? 105.254 131.631 68.777  1.00 361.79 ? 484 TRP B CE3 1 
ATOM   6979  C CZ2 . TRP B 2 484 ? 103.180 133.074 70.070  1.00 424.69 ? 484 TRP B CZ2 1 
ATOM   6980  C CZ3 . TRP B 2 484 ? 104.833 131.296 70.047  1.00 386.19 ? 484 TRP B CZ3 1 
ATOM   6981  C CH2 . TRP B 2 484 ? 103.810 132.011 70.684  1.00 423.94 ? 484 TRP B CH2 1 
ATOM   6982  N N   . LEU B 2 485 ? 104.137 130.151 66.172  1.00 427.55 ? 485 LEU B N   1 
ATOM   6983  C CA  . LEU B 2 485 ? 103.947 128.906 66.913  1.00 401.28 ? 485 LEU B CA  1 
ATOM   6984  C C   . LEU B 2 485 ? 104.108 127.710 65.967  1.00 390.37 ? 485 LEU B C   1 
ATOM   6985  O O   . LEU B 2 485 ? 104.813 126.761 66.318  1.00 411.31 ? 485 LEU B O   1 
ATOM   6986  C CB  . LEU B 2 485 ? 102.574 128.920 67.607  1.00 391.58 ? 485 LEU B CB  1 
ATOM   6987  C CG  . LEU B 2 485 ? 102.169 127.648 68.362  1.00 352.37 ? 485 LEU B CG  1 
ATOM   6988  C CD1 . LEU B 2 485 ? 103.069 127.410 69.567  1.00 353.18 ? 485 LEU B CD1 1 
ATOM   6989  C CD2 . LEU B 2 485 ? 100.706 127.707 68.782  1.00 344.58 ? 485 LEU B CD2 1 
ATOM   6990  N N   . LEU B 2 486 ? 103.468 127.767 64.782  1.00 394.44 ? 486 LEU B N   1 
ATOM   6991  C CA  . LEU B 2 486 ? 103.573 126.719 63.769  1.00 404.90 ? 486 LEU B CA  1 
ATOM   6992  C C   . LEU B 2 486 ? 105.025 126.568 63.285  1.00 343.34 ? 486 LEU B C   1 
ATOM   6993  O O   . LEU B 2 486 ? 105.488 125.435 63.129  1.00 283.00 ? 486 LEU B O   1 
ATOM   6994  C CB  . LEU B 2 486 ? 102.608 127.007 62.603  1.00 414.77 ? 486 LEU B CB  1 
ATOM   6995  C CG  . LEU B 2 486 ? 101.135 126.597 62.772  1.00 386.02 ? 486 LEU B CG  1 
ATOM   6996  C CD1 . LEU B 2 486 ? 100.982 125.089 62.968  1.00 328.48 ? 486 LEU B CD1 1 
ATOM   6997  C CD2 . LEU B 2 486 ? 100.448 127.347 63.911  1.00 386.11 ? 486 LEU B CD2 1 
ATOM   6998  N N   . GLN B 2 487 ? 105.738 127.688 63.066  1.00 352.11 ? 487 GLN B N   1 
ATOM   6999  C CA  . GLN B 2 487 ? 107.153 127.675 62.693  1.00 415.68 ? 487 GLN B CA  1 
ATOM   7000  C C   . GLN B 2 487 ? 108.010 127.012 63.783  1.00 432.94 ? 487 GLN B C   1 
ATOM   7001  O O   . GLN B 2 487 ? 108.941 126.274 63.449  1.00 471.99 ? 487 GLN B O   1 
ATOM   7002  C CB  . GLN B 2 487 ? 107.616 129.102 62.362  1.00 466.62 ? 487 GLN B CB  1 
ATOM   7003  C CG  . GLN B 2 487 ? 109.077 129.227 61.914  1.00 466.58 ? 487 GLN B CG  1 
ATOM   7004  C CD  . GLN B 2 487 ? 110.093 129.514 63.001  1.00 435.49 ? 487 GLN B CD  1 
ATOM   7005  O OE1 . GLN B 2 487 ? 109.783 129.574 64.189  1.00 395.17 ? 487 GLN B OE1 1 
ATOM   7006  N NE2 . GLN B 2 487 ? 111.342 129.699 62.599  1.00 410.26 ? 487 GLN B NE2 1 
ATOM   7007  N N   . GLY B 2 488 ? 107.696 127.270 65.069  1.00 392.77 ? 488 GLY B N   1 
ATOM   7008  C CA  . GLY B 2 488 ? 108.391 126.677 66.207  1.00 358.54 ? 488 GLY B CA  1 
ATOM   7009  C C   . GLY B 2 488 ? 108.158 125.171 66.345  1.00 309.01 ? 488 GLY B C   1 
ATOM   7010  O O   . GLY B 2 488 ? 109.109 124.417 66.547  1.00 224.48 ? 488 GLY B O   1 
ATOM   7011  N N   . ILE B 2 489 ? 106.891 124.746 66.239  1.00 343.54 ? 489 ILE B N   1 
ATOM   7012  C CA  . ILE B 2 489 ? 106.527 123.335 66.320  1.00 375.13 ? 489 ILE B CA  1 
ATOM   7013  C C   . ILE B 2 489 ? 107.188 122.563 65.174  1.00 343.40 ? 489 ILE B C   1 
ATOM   7014  O O   . ILE B 2 489 ? 107.721 121.483 65.412  1.00 320.45 ? 489 ILE B O   1 
ATOM   7015  C CB  . ILE B 2 489 ? 104.986 123.175 66.374  1.00 460.15 ? 489 ILE B CB  1 
ATOM   7016  C CG1 . ILE B 2 489 ? 104.420 123.667 67.717  1.00 436.40 ? 489 ILE B CG1 1 
ATOM   7017  C CG2 . ILE B 2 489 ? 104.522 121.750 66.068  1.00 482.52 ? 489 ILE B CG2 1 
ATOM   7018  C CD1 . ILE B 2 489 ? 104.770 122.823 68.945  1.00 368.04 ? 489 ILE B CD1 1 
ATOM   7019  N N   . PHE B 2 490 ? 107.164 123.110 63.950  1.00 353.95 ? 490 PHE B N   1 
ATOM   7020  C CA  . PHE B 2 490 ? 107.830 122.479 62.817  1.00 368.79 ? 490 PHE B CA  1 
ATOM   7021  C C   . PHE B 2 490 ? 109.345 122.393 63.054  1.00 380.46 ? 490 PHE B C   1 
ATOM   7022  O O   . PHE B 2 490 ? 109.926 121.319 62.899  1.00 423.79 ? 490 PHE B O   1 
ATOM   7023  C CB  . PHE B 2 490 ? 107.485 123.189 61.504  1.00 342.59 ? 490 PHE B CB  1 
ATOM   7024  C CG  . PHE B 2 490 ? 108.037 122.481 60.294  1.00 371.84 ? 490 PHE B CG  1 
ATOM   7025  C CD1 . PHE B 2 490 ? 109.312 122.775 59.822  1.00 403.26 ? 490 PHE B CD1 1 
ATOM   7026  C CD2 . PHE B 2 490 ? 107.295 121.505 59.636  1.00 345.75 ? 490 PHE B CD2 1 
ATOM   7027  C CE1 . PHE B 2 490 ? 109.827 122.117 58.711  1.00 401.81 ? 490 PHE B CE1 1 
ATOM   7028  C CE2 . PHE B 2 490 ? 107.812 120.849 58.525  1.00 345.40 ? 490 PHE B CE2 1 
ATOM   7029  C CZ  . PHE B 2 490 ? 109.078 121.152 58.066  1.00 365.05 ? 490 PHE B CZ  1 
ATOM   7030  N N   . SER B 2 491 ? 109.980 123.510 63.434  1.00 351.34 ? 491 SER B N   1 
ATOM   7031  C CA  . SER B 2 491 ? 111.419 123.545 63.696  1.00 342.57 ? 491 SER B CA  1 
ATOM   7032  C C   . SER B 2 491 ? 111.835 122.528 64.770  1.00 315.67 ? 491 SER B C   1 
ATOM   7033  O O   . SER B 2 491 ? 112.850 121.846 64.619  1.00 246.38 ? 491 SER B O   1 
ATOM   7034  C CB  . SER B 2 491 ? 111.867 124.941 64.070  1.00 377.73 ? 491 SER B CB  1 
ATOM   7035  O OG  . SER B 2 491 ? 111.567 125.871 63.037  1.00 382.23 ? 491 SER B OG  1 
ATOM   7036  N N   . THR B 2 492 ? 111.047 122.427 65.851  1.00 319.89 ? 492 THR B N   1 
ATOM   7037  C CA  . THR B 2 492 ? 111.286 121.459 66.916  1.00 308.31 ? 492 THR B CA  1 
ATOM   7038  C C   . THR B 2 492 ? 111.144 120.029 66.388  1.00 251.07 ? 492 THR B C   1 
ATOM   7039  O O   . THR B 2 492 ? 111.954 119.181 66.742  1.00 224.46 ? 492 THR B O   1 
ATOM   7040  C CB  . THR B 2 492 ? 110.354 121.712 68.112  1.00 354.56 ? 492 THR B CB  1 
ATOM   7041  O OG1 . THR B 2 492 ? 110.499 123.072 68.532  1.00 305.95 ? 492 THR B OG1 1 
ATOM   7042  C CG2 . THR B 2 492 ? 110.622 120.807 69.296  1.00 405.42 ? 492 THR B CG2 1 
ATOM   7043  N N   . THR B 2 493 ? 110.125 119.764 65.556  1.00 263.20 ? 493 THR B N   1 
ATOM   7044  C CA  . THR B 2 493 ? 109.880 118.439 64.993  1.00 277.52 ? 493 THR B CA  1 
ATOM   7045  C C   . THR B 2 493 ? 111.064 117.986 64.137  1.00 207.89 ? 493 THR B C   1 
ATOM   7046  O O   . THR B 2 493 ? 111.563 116.889 64.333  1.00 176.18 ? 493 THR B O   1 
ATOM   7047  C CB  . THR B 2 493 ? 108.568 118.393 64.187  1.00 316.00 ? 493 THR B CB  1 
ATOM   7048  O OG1 . THR B 2 493 ? 107.507 118.687 65.100  1.00 371.74 ? 493 THR B OG1 1 
ATOM   7049  C CG2 . THR B 2 493 ? 108.303 117.075 63.483  1.00 279.77 ? 493 THR B CG2 1 
ATOM   7050  N N   . VAL B 2 494 ? 111.511 118.827 63.201  1.00 240.75 ? 494 VAL B N   1 
ATOM   7051  C CA  . VAL B 2 494 ? 112.589 118.439 62.304  1.00 256.05 ? 494 VAL B CA  1 
ATOM   7052  C C   . VAL B 2 494 ? 113.897 118.305 63.083  1.00 222.03 ? 494 VAL B C   1 
ATOM   7053  O O   . VAL B 2 494 ? 114.719 117.474 62.704  1.00 177.01 ? 494 VAL B O   1 
ATOM   7054  C CB  . VAL B 2 494 ? 112.724 119.372 61.077  1.00 334.87 ? 494 VAL B CB  1 
ATOM   7055  C CG1 . VAL B 2 494 ? 111.447 119.380 60.248  1.00 333.64 ? 494 VAL B CG1 1 
ATOM   7056  C CG2 . VAL B 2 494 ? 113.137 120.797 61.421  1.00 347.92 ? 494 VAL B CG2 1 
ATOM   7057  N N   . LEU B 2 495 ? 114.099 119.104 64.145  1.00 234.83 ? 495 LEU B N   1 
ATOM   7058  C CA  . LEU B 2 495 ? 115.255 118.936 65.020  1.00 290.66 ? 495 LEU B CA  1 
ATOM   7059  C C   . LEU B 2 495 ? 115.242 117.529 65.634  1.00 275.14 ? 495 LEU B C   1 
ATOM   7060  O O   . LEU B 2 495 ? 116.269 116.852 65.619  1.00 202.36 ? 495 LEU B O   1 
ATOM   7061  C CB  . LEU B 2 495 ? 115.248 120.081 66.051  1.00 315.79 ? 495 LEU B CB  1 
ATOM   7062  C CG  . LEU B 2 495 ? 116.396 120.174 67.065  1.00 379.34 ? 495 LEU B CG  1 
ATOM   7063  C CD1 . LEU B 2 495 ? 116.187 119.232 68.252  1.00 441.00 ? 495 LEU B CD1 1 
ATOM   7064  C CD2 . LEU B 2 495 ? 117.758 119.929 66.412  1.00 347.69 ? 495 LEU B CD2 1 
ATOM   7065  N N   . CYS B 2 496 ? 114.089 117.079 66.156  1.00 277.52 ? 496 CYS B N   1 
ATOM   7066  C CA  . CYS B 2 496 ? 113.947 115.732 66.708  1.00 275.36 ? 496 CYS B CA  1 
ATOM   7067  C C   . CYS B 2 496 ? 114.199 114.651 65.650  1.00 256.18 ? 496 CYS B C   1 
ATOM   7068  O O   . CYS B 2 496 ? 114.832 113.628 65.952  1.00 214.02 ? 496 CYS B O   1 
ATOM   7069  C CB  . CYS B 2 496 ? 112.566 115.536 67.331  1.00 265.23 ? 496 CYS B CB  1 
ATOM   7070  S SG  . CYS B 2 496 ? 112.214 116.697 68.675  1.00 354.53 ? 496 CYS B SG  1 
ATOM   7071  N N   . GLN B 2 497 ? 113.706 114.879 64.420  1.00 250.65 ? 497 GLN B N   1 
ATOM   7072  C CA  . GLN B 2 497 ? 113.988 113.989 63.307  1.00 242.28 ? 497 GLN B CA  1 
ATOM   7073  C C   . GLN B 2 497 ? 115.492 113.866 63.098  1.00 232.03 ? 497 GLN B C   1 
ATOM   7074  O O   . GLN B 2 497 ? 115.942 112.750 62.908  1.00 176.04 ? 497 GLN B O   1 
ATOM   7075  C CB  . GLN B 2 497 ? 113.324 114.448 62.008  1.00 236.59 ? 497 GLN B CB  1 
ATOM   7076  C CG  . GLN B 2 497 ? 111.816 114.328 62.023  1.00 220.98 ? 497 GLN B CG  1 
ATOM   7077  C CD  . GLN B 2 497 ? 111.214 114.539 60.661  1.00 280.32 ? 497 GLN B CD  1 
ATOM   7078  O OE1 . GLN B 2 497 ? 110.678 115.601 60.358  1.00 361.32 ? 497 GLN B OE1 1 
ATOM   7079  N NE2 . GLN B 2 497 ? 111.304 113.525 59.817  1.00 280.38 ? 497 GLN B NE2 1 
ATOM   7080  N N   . LYS B 2 498 ? 116.233 114.991 63.131  1.00 235.48 ? 498 LYS B N   1 
ATOM   7081  C CA  . LYS B 2 498 ? 117.665 115.029 62.844  1.00 269.86 ? 498 LYS B CA  1 
ATOM   7082  C C   . LYS B 2 498 ? 118.456 114.240 63.887  1.00 287.92 ? 498 LYS B C   1 
ATOM   7083  O O   . LYS B 2 498 ? 119.379 113.511 63.519  1.00 310.14 ? 498 LYS B O   1 
ATOM   7084  C CB  . LYS B 2 498 ? 118.173 116.476 62.744  1.00 229.89 ? 498 LYS B CB  1 
ATOM   7085  C CG  . LYS B 2 498 ? 117.776 117.177 61.456  1.00 285.79 ? 498 LYS B CG  1 
ATOM   7086  C CD  . LYS B 2 498 ? 118.055 118.661 61.430  1.00 331.48 ? 498 LYS B CD  1 
ATOM   7087  C CE  . LYS B 2 498 ? 117.420 119.347 60.235  1.00 359.60 ? 498 LYS B CE  1 
ATOM   7088  N NZ  . LYS B 2 498 ? 117.997 120.686 59.947  1.00 334.08 ? 498 LYS B NZ  1 
ATOM   7089  N N   . LEU B 2 499 ? 118.092 114.389 65.169  1.00 261.02 ? 499 LEU B N   1 
ATOM   7090  C CA  . LEU B 2 499 ? 118.755 113.672 66.254  1.00 265.52 ? 499 LEU B CA  1 
ATOM   7091  C C   . LEU B 2 499 ? 118.545 112.163 66.113  1.00 257.56 ? 499 LEU B C   1 
ATOM   7092  O O   . LEU B 2 499 ? 119.522 111.418 66.027  1.00 247.07 ? 499 LEU B O   1 
ATOM   7093  C CB  . LEU B 2 499 ? 118.243 114.190 67.606  1.00 284.66 ? 499 LEU B CB  1 
ATOM   7094  C CG  . LEU B 2 499 ? 119.099 115.272 68.267  1.00 278.70 ? 499 LEU B CG  1 
ATOM   7095  C CD1 . LEU B 2 499 ? 119.093 116.560 67.460  1.00 320.55 ? 499 LEU B CD1 1 
ATOM   7096  C CD2 . LEU B 2 499 ? 118.624 115.546 69.689  1.00 293.41 ? 499 LEU B CD2 1 
ATOM   7097  N N   . MET B 2 500 ? 117.276 111.733 66.079  1.00 219.92 ? 500 MET B N   1 
ATOM   7098  C CA  . MET B 2 500 ? 116.921 110.321 66.170  1.00 266.90 ? 500 MET B CA  1 
ATOM   7099  C C   . MET B 2 500 ? 116.976 109.610 64.806  1.00 296.82 ? 500 MET B C   1 
ATOM   7100  O O   . MET B 2 500 ? 116.966 108.377 64.771  1.00 302.45 ? 500 MET B O   1 
ATOM   7101  C CB  . MET B 2 500 ? 115.512 110.209 66.762  1.00 290.17 ? 500 MET B CB  1 
ATOM   7102  C CG  . MET B 2 500 ? 115.420 110.709 68.216  1.00 245.42 ? 500 MET B CG  1 
ATOM   7103  S SD  . MET B 2 500 ? 113.748 110.590 68.979  1.00 204.79 ? 500 MET B SD  1 
ATOM   7104  C CE  . MET B 2 500 ? 113.805 111.981 70.114  1.00 238.83 ? 500 MET B CE  1 
ATOM   7105  N N   . GLN B 2 501 ? 117.029 110.382 63.702  1.00 275.44 ? 501 GLN B N   1 
ATOM   7106  C CA  . GLN B 2 501 ? 116.994 109.902 62.320  1.00 268.33 ? 501 GLN B CA  1 
ATOM   7107  C C   . GLN B 2 501 ? 115.688 109.139 62.080  1.00 255.73 ? 501 GLN B C   1 
ATOM   7108  O O   . GLN B 2 501 ? 115.696 107.928 61.902  1.00 187.55 ? 501 GLN B O   1 
ATOM   7109  C CB  . GLN B 2 501 ? 118.269 109.108 62.018  1.00 285.77 ? 501 GLN B CB  1 
ATOM   7110  C CG  . GLN B 2 501 ? 118.485 108.787 60.546  1.00 292.47 ? 501 GLN B CG  1 
ATOM   7111  C CD  . GLN B 2 501 ? 119.690 107.897 60.331  1.00 305.95 ? 501 GLN B CD  1 
ATOM   7112  O OE1 . GLN B 2 501 ? 120.544 107.740 61.205  1.00 322.30 ? 501 GLN B OE1 1 
ATOM   7113  N NE2 . GLN B 2 501 ? 119.772 107.294 59.155  1.00 292.20 ? 501 GLN B NE2 1 
ATOM   7114  N N   . VAL B 2 502 ? 114.562 109.866 62.081  1.00 268.16 ? 502 VAL B N   1 
ATOM   7115  C CA  . VAL B 2 502 ? 113.250 109.246 61.942  1.00 269.77 ? 502 VAL B CA  1 
ATOM   7116  C C   . VAL B 2 502 ? 112.416 109.916 60.849  1.00 279.77 ? 502 VAL B C   1 
ATOM   7117  O O   . VAL B 2 502 ? 112.489 111.123 60.630  1.00 241.02 ? 502 VAL B O   1 
ATOM   7118  C CB  . VAL B 2 502 ? 112.488 109.223 63.281  1.00 228.56 ? 502 VAL B CB  1 
ATOM   7119  C CG1 . VAL B 2 502 ? 113.226 108.347 64.280  1.00 250.00 ? 502 VAL B CG1 1 
ATOM   7120  C CG2 . VAL B 2 502 ? 112.230 110.608 63.851  1.00 194.70 ? 502 VAL B CG2 1 
ATOM   7121  N N   . VAL B 2 503 ? 111.595 109.085 60.194  1.00 250.08 ? 503 VAL B N   1 
ATOM   7122  C CA  . VAL B 2 503 ? 110.833 109.420 59.006  1.00 193.57 ? 503 VAL B CA  1 
ATOM   7123  C C   . VAL B 2 503 ? 109.378 109.117 59.299  1.00 190.88 ? 503 VAL B C   1 
ATOM   7124  O O   . VAL B 2 503 ? 109.088 108.155 60.014  1.00 303.71 ? 503 VAL B O   1 
ATOM   7125  C CB  . VAL B 2 503 ? 111.336 108.604 57.802  1.00 235.77 ? 503 VAL B CB  1 
ATOM   7126  C CG1 . VAL B 2 503 ? 112.804 108.900 57.556  1.00 325.07 ? 503 VAL B CG1 1 
ATOM   7127  C CG2 . VAL B 2 503 ? 111.130 107.095 57.925  1.00 174.92 ? 503 VAL B CG2 1 
ATOM   7128  N N   . PRO B 2 504 ? 108.409 109.893 58.787  1.00 214.49 ? 504 PRO B N   1 
ATOM   7129  C CA  . PRO B 2 504 ? 107.001 109.577 59.044  1.00 275.08 ? 504 PRO B CA  1 
ATOM   7130  C C   . PRO B 2 504 ? 106.551 108.294 58.322  1.00 263.45 ? 504 PRO B C   1 
ATOM   7131  O O   . PRO B 2 504 ? 107.165 107.842 57.359  1.00 181.65 ? 504 PRO B O   1 
ATOM   7132  C CB  . PRO B 2 504 ? 106.273 110.866 58.614  1.00 290.01 ? 504 PRO B CB  1 
ATOM   7133  C CG  . PRO B 2 504 ? 107.191 111.493 57.587  1.00 324.46 ? 504 PRO B CG  1 
ATOM   7134  C CD  . PRO B 2 504 ? 108.601 111.094 57.971  1.00 255.79 ? 504 PRO B CD  1 
ATOM   7135  N N   . GLN B 2 505 ? 105.461 107.714 58.836  1.00 275.55 ? 505 GLN B N   1 
ATOM   7136  C CA  . GLN B 2 505 ? 104.840 106.484 58.358  1.00 302.03 ? 505 GLN B CA  1 
ATOM   7137  C C   . GLN B 2 505 ? 104.218 106.700 56.975  1.00 348.16 ? 505 GLN B C   1 
ATOM   7138  O O   . GLN B 2 505 ? 103.677 107.777 56.713  1.00 365.89 ? 505 GLN B O   1 
ATOM   7139  C CB  . GLN B 2 505 ? 103.803 106.103 59.422  1.00 369.10 ? 505 GLN B CB  1 
ATOM   7140  C CG  . GLN B 2 505 ? 102.945 104.860 59.167  1.00 382.51 ? 505 GLN B CG  1 
ATOM   7141  C CD  . GLN B 2 505 ? 101.959 104.532 60.270  1.00 405.66 ? 505 GLN B CD  1 
ATOM   7142  O OE1 . GLN B 2 505 ? 101.204 103.565 60.178  1.00 336.99 ? 505 GLN B OE1 1 
ATOM   7143  N NE2 . GLN B 2 505 ? 101.944 105.327 61.332  1.00 446.89 ? 505 GLN B NE2 1 
ATOM   7144  N N   . GLU B 2 506 ? 104.284 105.677 56.097  1.00 366.72 ? 506 GLU B N   1 
ATOM   7145  C CA  . GLU B 2 506 ? 103.831 105.791 54.711  1.00 389.32 ? 506 GLU B CA  1 
ATOM   7146  C C   . GLU B 2 506 ? 102.832 104.688 54.330  1.00 436.51 ? 506 GLU B C   1 
ATOM   7147  O O   . GLU B 2 506 ? 103.000 103.529 54.724  1.00 481.28 ? 506 GLU B O   1 
ATOM   7148  C CB  . GLU B 2 506 ? 105.021 105.760 53.747  1.00 384.67 ? 506 GLU B CB  1 
ATOM   7149  C CG  . GLU B 2 506 ? 106.030 106.889 53.943  1.00 444.17 ? 506 GLU B CG  1 
ATOM   7150  C CD  . GLU B 2 506 ? 105.593 108.309 53.605  1.00 473.15 ? 506 GLU B CD  1 
ATOM   7151  O OE1 . GLU B 2 506 ? 104.385 108.549 53.398  1.00 449.92 ? 506 GLU B OE1 1 
ATOM   7152  O OE2 . GLU B 2 506 ? 106.479 109.188 53.544  1.00 477.95 ? 506 GLU B OE2 1 
ATOM   7153  N N   . THR B 2 507 ? 101.802 105.104 53.554  1.00 437.75 ? 507 THR B N   1 
ATOM   7154  C CA  . THR B 2 507 ? 100.724 104.296 52.971  1.00 409.42 ? 507 THR B CA  1 
ATOM   7155  C C   . THR B 2 507 ? 100.177 103.278 53.995  1.00 334.62 ? 507 THR B C   1 
ATOM   7156  O O   . THR B 2 507 ? 100.468 102.065 53.864  1.00 299.67 ? 507 THR B O   1 
ATOM   7157  C CB  . THR B 2 507 ? 101.155 103.703 51.613  1.00 410.08 ? 507 THR B CB  1 
ATOM   7158  O OG1 . THR B 2 507 ? 101.665 104.739 50.770  1.00 378.98 ? 507 THR B OG1 1 
ATOM   7159  C CG2 . THR B 2 507 ? 100.027 103.027 50.861  1.00 393.36 ? 507 THR B CG2 1 
ATOM   7160  N N   . ASP C 3 1   ? 97.323  121.154 132.673 1.00 270.88 ? 1   ASP L N   1 
ATOM   7161  C CA  . ASP C 3 1   ? 97.474  121.023 134.149 1.00 224.91 ? 1   ASP L CA  1 
ATOM   7162  C C   . ASP C 3 1   ? 96.114  121.224 134.809 1.00 157.69 ? 1   ASP L C   1 
ATOM   7163  O O   . ASP C 3 1   ? 95.227  121.858 134.236 1.00 200.69 ? 1   ASP L O   1 
ATOM   7164  C CB  . ASP C 3 1   ? 98.483  122.039 134.711 1.00 283.98 ? 1   ASP L CB  1 
ATOM   7165  C CG  . ASP C 3 1   ? 99.852  122.069 134.038 1.00 395.00 ? 1   ASP L CG  1 
ATOM   7166  O OD1 . ASP C 3 1   ? 100.037 121.348 133.035 1.00 478.27 ? 1   ASP L OD1 1 
ATOM   7167  O OD2 . ASP C 3 1   ? 100.730 122.818 134.520 1.00 423.80 ? 1   ASP L OD2 1 
ATOM   7168  N N   . ILE C 3 2   ? 95.951  120.700 136.030 1.00 117.78 ? 2   ILE L N   1 
ATOM   7169  C CA  . ILE C 3 2   ? 94.846  121.103 136.918 1.00 89.83  ? 2   ILE L CA  1 
ATOM   7170  C C   . ILE C 3 2   ? 94.989  122.582 137.302 1.00 116.75 ? 2   ILE L C   1 
ATOM   7171  O O   . ILE C 3 2   ? 96.103  123.135 137.338 1.00 139.54 ? 2   ILE L O   1 
ATOM   7172  C CB  . ILE C 3 2   ? 94.797  120.183 138.152 1.00 83.81  ? 2   ILE L CB  1 
ATOM   7173  C CG1 . ILE C 3 2   ? 94.396  118.791 137.723 1.00 134.35 ? 2   ILE L CG1 1 
ATOM   7174  C CG2 . ILE C 3 2   ? 93.877  120.629 139.260 1.00 77.59  ? 2   ILE L CG2 1 
ATOM   7175  C CD1 . ILE C 3 2   ? 94.693  117.756 138.731 1.00 129.91 ? 2   ILE L CD1 1 
ATOM   7176  N N   . VAL C 3 3   ? 93.840  123.227 137.571 1.00 107.25 ? 3   VAL L N   1 
ATOM   7177  C CA  . VAL C 3 3   ? 93.788  124.624 137.995 1.00 142.71 ? 3   VAL L CA  1 
ATOM   7178  C C   . VAL C 3 3   ? 92.945  124.667 139.248 1.00 136.11 ? 3   VAL L C   1 
ATOM   7179  O O   . VAL C 3 3   ? 91.870  124.047 139.237 1.00 164.72 ? 3   VAL L O   1 
ATOM   7180  C CB  . VAL C 3 3   ? 93.196  125.550 136.918 1.00 157.78 ? 3   VAL L CB  1 
ATOM   7181  C CG1 . VAL C 3 3   ? 92.919  126.954 137.455 1.00 207.82 ? 3   VAL L CG1 1 
ATOM   7182  C CG2 . VAL C 3 3   ? 94.090  125.558 135.677 1.00 199.50 ? 3   VAL L CG2 1 
ATOM   7183  N N   . LEU C 3 4   ? 93.444  125.382 140.280 1.00 117.23 ? 4   LEU L N   1 
ATOM   7184  C CA  . LEU C 3 4   ? 92.726  125.443 141.545 1.00 125.15 ? 4   LEU L CA  1 
ATOM   7185  C C   . LEU C 3 4   ? 92.349  126.894 141.811 1.00 128.95 ? 4   LEU L C   1 
ATOM   7186  O O   . LEU C 3 4   ? 93.172  127.712 142.132 1.00 182.38 ? 4   LEU L O   1 
ATOM   7187  C CB  . LEU C 3 4   ? 93.522  124.762 142.672 1.00 126.10 ? 4   LEU L CB  1 
ATOM   7188  C CG  . LEU C 3 4   ? 93.664  123.230 142.510 1.00 124.78 ? 4   LEU L CG  1 
ATOM   7189  C CD1 . LEU C 3 4   ? 95.028  122.929 141.943 1.00 151.14 ? 4   LEU L CD1 1 
ATOM   7190  C CD2 . LEU C 3 4   ? 93.416  122.390 143.773 1.00 87.09  ? 4   LEU L CD2 1 
ATOM   7191  N N   . THR C 3 5   ? 91.062  127.205 141.634 1.00 159.07 ? 5   THR L N   1 
ATOM   7192  C CA  . THR C 3 5   ? 90.495  128.463 142.064 1.00 148.31 ? 5   THR L CA  1 
ATOM   7193  C C   . THR C 3 5   ? 90.292  128.380 143.576 1.00 108.68 ? 5   THR L C   1 
ATOM   7194  O O   . THR C 3 5   ? 89.895  127.360 144.125 1.00 114.50 ? 5   THR L O   1 
ATOM   7195  C CB  . THR C 3 5   ? 89.185  128.731 141.315 1.00 253.96 ? 5   THR L CB  1 
ATOM   7196  O OG1 . THR C 3 5   ? 89.517  128.900 139.933 1.00 267.03 ? 5   THR L OG1 1 
ATOM   7197  C CG2 . THR C 3 5   ? 88.434  129.960 141.794 1.00 311.46 ? 5   THR L CG2 1 
ATOM   7198  N N   . GLN C 3 6   ? 90.553  129.481 144.246 1.00 104.02 ? 6   GLN L N   1 
ATOM   7199  C CA  . GLN C 3 6   ? 90.350  129.569 145.669 1.00 115.19 ? 6   GLN L CA  1 
ATOM   7200  C C   . GLN C 3 6   ? 89.537  130.818 146.002 1.00 143.63 ? 6   GLN L C   1 
ATOM   7201  O O   . GLN C 3 6   ? 89.716  131.863 145.381 1.00 196.62 ? 6   GLN L O   1 
ATOM   7202  C CB  . GLN C 3 6   ? 91.733  129.614 146.313 1.00 137.89 ? 6   GLN L CB  1 
ATOM   7203  C CG  . GLN C 3 6   ? 91.710  129.095 147.736 1.00 156.45 ? 6   GLN L CG  1 
ATOM   7204  C CD  . GLN C 3 6   ? 93.052  129.066 148.423 1.00 124.30 ? 6   GLN L CD  1 
ATOM   7205  O OE1 . GLN C 3 6   ? 94.072  128.662 147.870 1.00 90.52  ? 6   GLN L OE1 1 
ATOM   7206  N NE2 . GLN C 3 6   ? 93.063  129.522 149.664 1.00 143.14 ? 6   GLN L NE2 1 
ATOM   7207  N N   . SER C 3 7   ? 88.662  130.709 147.009 1.00 166.28 ? 7   SER L N   1 
ATOM   7208  C CA  . SER C 3 7   ? 87.846  131.839 147.434 1.00 168.42 ? 7   SER L CA  1 
ATOM   7209  C C   . SER C 3 7   ? 87.407  131.710 148.896 1.00 158.95 ? 7   SER L C   1 
ATOM   7210  O O   . SER C 3 7   ? 87.401  130.613 149.459 1.00 179.35 ? 7   SER L O   1 
ATOM   7211  C CB  . SER C 3 7   ? 86.650  131.981 146.510 1.00 215.42 ? 7   SER L CB  1 
ATOM   7212  O OG  . SER C 3 7   ? 85.678  130.967 146.733 1.00 258.32 ? 7   SER L OG  1 
ATOM   7213  N N   . PRO C 3 8   ? 87.030  132.817 149.579 1.00 170.82 ? 8   PRO L N   1 
ATOM   7214  C CA  . PRO C 3 8   ? 87.272  134.186 149.109 1.00 167.08 ? 8   PRO L CA  1 
ATOM   7215  C C   . PRO C 3 8   ? 88.754  134.533 149.227 1.00 164.96 ? 8   PRO L C   1 
ATOM   7216  O O   . PRO C 3 8   ? 89.486  133.871 149.964 1.00 225.61 ? 8   PRO L O   1 
ATOM   7217  C CB  . PRO C 3 8   ? 86.429  135.023 150.069 1.00 214.34 ? 8   PRO L CB  1 
ATOM   7218  C CG  . PRO C 3 8   ? 86.472  134.221 151.359 1.00 214.78 ? 8   PRO L CG  1 
ATOM   7219  C CD  . PRO C 3 8   ? 86.349  132.792 150.883 1.00 200.00 ? 8   PRO L CD  1 
ATOM   7220  N N   . SER C 3 9   ? 89.197  135.562 148.495 1.00 156.87 ? 9   SER L N   1 
ATOM   7221  C CA  . SER C 3 9   ? 90.593  135.986 148.537 1.00 186.20 ? 9   SER L CA  1 
ATOM   7222  C C   . SER C 3 9   ? 90.971  136.628 149.885 1.00 166.35 ? 9   SER L C   1 
ATOM   7223  O O   . SER C 3 9   ? 92.140  136.570 150.287 1.00 237.67 ? 9   SER L O   1 
ATOM   7224  C CB  . SER C 3 9   ? 90.899  136.895 147.387 1.00 201.36 ? 9   SER L CB  1 
ATOM   7225  O OG  . SER C 3 9   ? 90.142  138.088 147.496 1.00 287.01 ? 9   SER L OG  1 
ATOM   7226  N N   . SER C 3 10  ? 89.989  137.223 150.573 1.00 142.88 ? 10  SER L N   1 
ATOM   7227  C CA  . SER C 3 10  ? 90.129  137.725 151.930 1.00 160.45 ? 10  SER L CA  1 
ATOM   7228  C C   . SER C 3 10  ? 89.031  137.138 152.812 1.00 150.74 ? 10  SER L C   1 
ATOM   7229  O O   . SER C 3 10  ? 87.909  136.982 152.357 1.00 158.81 ? 10  SER L O   1 
ATOM   7230  C CB  . SER C 3 10  ? 90.095  139.249 151.947 1.00 192.34 ? 10  SER L CB  1 
ATOM   7231  O OG  . SER C 3 10  ? 89.903  139.776 153.266 1.00 203.34 ? 10  SER L OG  1 
ATOM   7232  N N   . LEU C 3 11  ? 89.344  136.842 154.070 1.00 150.34 ? 11  LEU L N   1 
ATOM   7233  C CA  . LEU C 3 11  ? 88.332  136.340 154.981 1.00 133.65 ? 11  LEU L CA  1 
ATOM   7234  C C   . LEU C 3 11  ? 88.588  136.926 156.358 1.00 148.95 ? 11  LEU L C   1 
ATOM   7235  O O   . LEU C 3 11  ? 89.226  136.302 157.201 1.00 226.55 ? 11  LEU L O   1 
ATOM   7236  C CB  . LEU C 3 11  ? 88.451  134.821 154.936 1.00 154.42 ? 11  LEU L CB  1 
ATOM   7237  C CG  . LEU C 3 11  ? 87.693  134.018 155.982 1.00 217.19 ? 11  LEU L CG  1 
ATOM   7238  C CD1 . LEU C 3 11  ? 86.201  134.241 155.831 1.00 264.47 ? 11  LEU L CD1 1 
ATOM   7239  C CD2 . LEU C 3 11  ? 88.079  132.545 155.868 1.00 254.15 ? 11  LEU L CD2 1 
ATOM   7240  N N   . ALA C 3 12  ? 88.106  138.151 156.601 1.00 188.10 ? 12  ALA L N   1 
ATOM   7241  C CA  . ALA C 3 12  ? 88.328  138.777 157.908 1.00 227.98 ? 12  ALA L CA  1 
ATOM   7242  C C   . ALA C 3 12  ? 87.387  138.130 158.924 1.00 164.97 ? 12  ALA L C   1 
ATOM   7243  O O   . ALA C 3 12  ? 86.187  138.123 158.655 1.00 163.23 ? 12  ALA L O   1 
ATOM   7244  C CB  . ALA C 3 12  ? 88.119  140.272 157.833 1.00 235.92 ? 12  ALA L CB  1 
ATOM   7245  N N   . MET C 3 13  ? 87.924  137.590 160.045 1.00 157.65 ? 13  MET L N   1 
ATOM   7246  C CA  . MET C 3 13  ? 87.090  137.021 161.099 1.00 182.38 ? 13  MET L CA  1 
ATOM   7247  C C   . MET C 3 13  ? 87.642  137.264 162.501 1.00 180.15 ? 13  MET L C   1 
ATOM   7248  O O   . MET C 3 13  ? 88.807  137.529 162.666 1.00 165.66 ? 13  MET L O   1 
ATOM   7249  C CB  . MET C 3 13  ? 86.868  135.529 160.863 1.00 165.96 ? 13  MET L CB  1 
ATOM   7250  C CG  . MET C 3 13  ? 85.606  135.275 159.958 1.00 297.93 ? 13  MET L CG  1 
ATOM   7251  S SD  . MET C 3 13  ? 83.952  135.948 160.467 1.00 389.70 ? 13  MET L SD  1 
ATOM   7252  C CE  . MET C 3 13  ? 83.564  135.003 161.937 1.00 383.47 ? 13  MET L CE  1 
ATOM   7253  N N   . SER C 3 14  ? 86.751  137.189 163.505 1.00 222.22 ? 14  SER L N   1 
ATOM   7254  C CA  . SER C 3 14  ? 87.014  137.613 164.878 1.00 222.20 ? 14  SER L CA  1 
ATOM   7255  C C   . SER C 3 14  ? 87.564  136.450 165.699 1.00 190.79 ? 14  SER L C   1 
ATOM   7256  O O   . SER C 3 14  ? 87.287  135.286 165.397 1.00 158.58 ? 14  SER L O   1 
ATOM   7257  C CB  . SER C 3 14  ? 85.772  138.161 165.534 1.00 234.46 ? 14  SER L CB  1 
ATOM   7258  O OG  . SER C 3 14  ? 85.160  139.162 164.736 1.00 223.51 ? 14  SER L OG  1 
ATOM   7259  N N   . VAL C 3 15  ? 88.325  136.775 166.755 1.00 149.49 ? 15  VAL L N   1 
ATOM   7260  C CA  . VAL C 3 15  ? 89.007  135.756 167.543 1.00 163.38 ? 15  VAL L CA  1 
ATOM   7261  C C   . VAL C 3 15  ? 87.957  134.872 168.217 1.00 188.67 ? 15  VAL L C   1 
ATOM   7262  O O   . VAL C 3 15  ? 86.951  135.382 168.720 1.00 247.93 ? 15  VAL L O   1 
ATOM   7263  C CB  . VAL C 3 15  ? 89.954  136.384 168.590 1.00 209.91 ? 15  VAL L CB  1 
ATOM   7264  C CG1 . VAL C 3 15  ? 90.582  135.331 169.516 1.00 196.73 ? 15  VAL L CG1 1 
ATOM   7265  C CG2 . VAL C 3 15  ? 91.025  137.246 167.936 1.00 245.43 ? 15  VAL L CG2 1 
ATOM   7266  N N   . GLY C 3 16  ? 88.203  133.553 168.231 1.00 185.48 ? 16  GLY L N   1 
ATOM   7267  C CA  . GLY C 3 16  ? 87.285  132.579 168.799 1.00 206.19 ? 16  GLY L CA  1 
ATOM   7268  C C   . GLY C 3 16  ? 86.321  131.953 167.781 1.00 218.80 ? 16  GLY L C   1 
ATOM   7269  O O   . GLY C 3 16  ? 85.808  130.863 168.059 1.00 230.18 ? 16  GLY L O   1 
ATOM   7270  N N   . GLN C 3 17  ? 86.070  132.621 166.633 1.00 176.57 ? 17  GLN L N   1 
ATOM   7271  C CA  . GLN C 3 17  ? 85.057  132.192 165.678 1.00 206.09 ? 17  GLN L CA  1 
ATOM   7272  C C   . GLN C 3 17  ? 85.592  131.096 164.751 1.00 198.52 ? 17  GLN L C   1 
ATOM   7273  O O   . GLN C 3 17  ? 86.792  130.930 164.579 1.00 174.04 ? 17  GLN L O   1 
ATOM   7274  C CB  . GLN C 3 17  ? 84.562  133.386 164.852 1.00 206.93 ? 17  GLN L CB  1 
ATOM   7275  C CG  . GLN C 3 17  ? 83.930  134.491 165.685 1.00 239.95 ? 17  GLN L CG  1 
ATOM   7276  C CD  . GLN C 3 17  ? 82.660  134.077 166.383 1.00 328.66 ? 17  GLN L CD  1 
ATOM   7277  O OE1 . GLN C 3 17  ? 82.010  133.104 166.005 1.00 352.30 ? 17  GLN L OE1 1 
ATOM   7278  N NE2 . GLN C 3 17  ? 82.290  134.824 167.414 1.00 372.39 ? 17  GLN L NE2 1 
ATOM   7279  N N   . LYS C 3 18  ? 84.652  130.355 164.147 1.00 194.85 ? 18  LYS L N   1 
ATOM   7280  C CA  . LYS C 3 18  ? 84.920  129.356 163.127 1.00 164.91 ? 18  LYS L CA  1 
ATOM   7281  C C   . LYS C 3 18  ? 85.008  130.029 161.755 1.00 202.48 ? 18  LYS L C   1 
ATOM   7282  O O   . LYS C 3 18  ? 84.210  130.934 161.468 1.00 155.07 ? 18  LYS L O   1 
ATOM   7283  C CB  . LYS C 3 18  ? 83.780  128.333 163.120 1.00 204.55 ? 18  LYS L CB  1 
ATOM   7284  C CG  . LYS C 3 18  ? 83.824  127.264 162.039 1.00 246.57 ? 18  LYS L CG  1 
ATOM   7285  C CD  . LYS C 3 18  ? 82.777  126.186 162.247 1.00 254.91 ? 18  LYS L CD  1 
ATOM   7286  C CE  . LYS C 3 18  ? 82.859  125.075 161.223 1.00 283.16 ? 18  LYS L CE  1 
ATOM   7287  N NZ  . LYS C 3 18  ? 82.290  123.808 161.743 1.00 314.93 ? 18  LYS L NZ  1 
ATOM   7288  N N   . VAL C 3 19  ? 85.963  129.565 160.908 1.00 218.37 ? 19  VAL L N   1 
ATOM   7289  C CA  . VAL C 3 19  ? 86.206  130.118 159.567 1.00 192.81 ? 19  VAL L CA  1 
ATOM   7290  C C   . VAL C 3 19  ? 86.457  129.018 158.548 1.00 171.56 ? 19  VAL L C   1 
ATOM   7291  O O   . VAL C 3 19  ? 86.889  127.919 158.916 1.00 182.56 ? 19  VAL L O   1 
ATOM   7292  C CB  . VAL C 3 19  ? 87.403  131.073 159.524 1.00 178.43 ? 19  VAL L CB  1 
ATOM   7293  C CG1 . VAL C 3 19  ? 87.282  132.108 160.612 1.00 266.23 ? 19  VAL L CG1 1 
ATOM   7294  C CG2 . VAL C 3 19  ? 88.735  130.368 159.662 1.00 149.49 ? 19  VAL L CG2 1 
ATOM   7295  N N   . THR C 3 20  ? 86.182  129.362 157.283 1.00 132.15 ? 20  THR L N   1 
ATOM   7296  C CA  . THR C 3 20  ? 86.137  128.396 156.199 1.00 143.60 ? 20  THR L CA  1 
ATOM   7297  C C   . THR C 3 20  ? 86.788  128.985 154.951 1.00 175.29 ? 20  THR L C   1 
ATOM   7298  O O   . THR C 3 20  ? 86.398  130.074 154.522 1.00 247.81 ? 20  THR L O   1 
ATOM   7299  C CB  . THR C 3 20  ? 84.690  127.997 155.894 1.00 207.15 ? 20  THR L CB  1 
ATOM   7300  O OG1 . THR C 3 20  ? 84.105  127.385 157.050 1.00 218.10 ? 20  THR L OG1 1 
ATOM   7301  C CG2 . THR C 3 20  ? 84.579  127.040 154.723 1.00 291.39 ? 20  THR L CG2 1 
ATOM   7302  N N   . MET C 3 21  ? 87.763  128.253 154.385 1.00 132.48 ? 21  MET L N   1 
ATOM   7303  C CA  . MET C 3 21  ? 88.354  128.536 153.081 1.00 115.02 ? 21  MET L CA  1 
ATOM   7304  C C   . MET C 3 21  ? 87.727  127.557 152.085 1.00 134.49 ? 21  MET L C   1 
ATOM   7305  O O   . MET C 3 21  ? 87.459  126.396 152.457 1.00 114.79 ? 21  MET L O   1 
ATOM   7306  C CB  . MET C 3 21  ? 89.861  128.303 153.051 1.00 119.90 ? 21  MET L CB  1 
ATOM   7307  C CG  . MET C 3 21  ? 90.580  128.397 154.385 1.00 118.93 ? 21  MET L CG  1 
ATOM   7308  S SD  . MET C 3 21  ? 91.017  130.055 154.796 1.00 142.35 ? 21  MET L SD  1 
ATOM   7309  C CE  . MET C 3 21  ? 91.870  129.719 156.349 1.00 90.15  ? 21  MET L CE  1 
ATOM   7310  N N   . ASN C 3 22  ? 87.503  128.008 150.835 1.00 111.08 ? 22  ASN L N   1 
ATOM   7311  C CA  . ASN C 3 22  ? 87.050  127.100 149.781 1.00 135.60 ? 22  ASN L CA  1 
ATOM   7312  C C   . ASN C 3 22  ? 88.125  126.954 148.704 1.00 122.56 ? 22  ASN L C   1 
ATOM   7313  O O   . ASN C 3 22  ? 88.747  127.934 148.314 1.00 147.54 ? 22  ASN L O   1 
ATOM   7314  C CB  . ASN C 3 22  ? 85.722  127.518 149.146 1.00 152.24 ? 22  ASN L CB  1 
ATOM   7315  C CG  . ASN C 3 22  ? 84.558  127.380 150.109 1.00 192.44 ? 22  ASN L CG  1 
ATOM   7316  O OD1 . ASN C 3 22  ? 83.989  126.300 150.226 1.00 183.74 ? 22  ASN L OD1 1 
ATOM   7317  N ND2 . ASN C 3 22  ? 84.189  128.451 150.802 1.00 230.19 ? 22  ASN L ND2 1 
ATOM   7318  N N   . CYS C 3 23  ? 88.314  125.716 148.241 1.00 116.54 ? 23  CYS L N   1 
ATOM   7319  C CA  . CYS C 3 23  ? 89.195  125.377 147.145 1.00 115.33 ? 23  CYS L CA  1 
ATOM   7320  C C   . CYS C 3 23  ? 88.416  124.579 146.122 1.00 116.34 ? 23  CYS L C   1 
ATOM   7321  O O   . CYS C 3 23  ? 87.657  123.702 146.515 1.00 163.88 ? 23  CYS L O   1 
ATOM   7322  C CB  . CYS C 3 23  ? 90.375  124.535 147.617 1.00 109.84 ? 23  CYS L CB  1 
ATOM   7323  S SG  . CYS C 3 23  ? 91.572  124.214 146.269 1.00 197.44 ? 23  CYS L SG  1 
ATOM   7324  N N   . LYS C 3 24  ? 88.620  124.885 144.840 1.00 107.68 ? 24  LYS L N   1 
ATOM   7325  C CA  . LYS C 3 24  ? 87.792  124.361 143.775 1.00 138.40 ? 24  LYS L CA  1 
ATOM   7326  C C   . LYS C 3 24  ? 88.673  123.989 142.577 1.00 131.24 ? 24  LYS L C   1 
ATOM   7327  O O   . LYS C 3 24  ? 89.215  124.887 141.915 1.00 176.32 ? 24  LYS L O   1 
ATOM   7328  C CB  . LYS C 3 24  ? 86.734  125.422 143.439 1.00 209.89 ? 24  LYS L CB  1 
ATOM   7329  C CG  . LYS C 3 24  ? 85.743  125.078 142.329 1.00 231.56 ? 24  LYS L CG  1 
ATOM   7330  C CD  . LYS C 3 24  ? 84.916  123.859 142.640 1.00 257.95 ? 24  LYS L CD  1 
ATOM   7331  C CE  . LYS C 3 24  ? 83.793  123.641 141.650 1.00 293.18 ? 24  LYS L CE  1 
ATOM   7332  N NZ  . LYS C 3 24  ? 82.974  122.461 142.016 1.00 314.26 ? 24  LYS L NZ  1 
ATOM   7333  N N   . SER C 3 25  ? 88.773  122.676 142.304 1.00 117.58 ? 25  SER L N   1 
ATOM   7334  C CA  . SER C 3 25  ? 89.678  122.115 141.313 1.00 125.55 ? 25  SER L CA  1 
ATOM   7335  C C   . SER C 3 25  ? 89.018  121.831 139.955 1.00 123.62 ? 25  SER L C   1 
ATOM   7336  O O   . SER C 3 25  ? 87.934  121.260 139.873 1.00 144.72 ? 25  SER L O   1 
ATOM   7337  C CB  . SER C 3 25  ? 90.274  120.856 141.864 1.00 132.97 ? 25  SER L CB  1 
ATOM   7338  O OG  . SER C 3 25  ? 89.253  119.932 142.132 1.00 123.90 ? 25  SER L OG  1 
ATOM   7339  N N   . SER C 3 26  ? 89.718  122.198 138.877 1.00 115.19 ? 26  SER L N   1 
ATOM   7340  C CA  . SER C 3 26  ? 89.290  121.939 137.510 1.00 155.12 ? 26  SER L CA  1 
ATOM   7341  C C   . SER C 3 26  ? 89.292  120.460 137.082 1.00 149.04 ? 26  SER L C   1 
ATOM   7342  O O   . SER C 3 26  ? 88.966  120.173 135.929 1.00 219.43 ? 26  SER L O   1 
ATOM   7343  C CB  . SER C 3 26  ? 90.152  122.736 136.555 1.00 225.31 ? 26  SER L CB  1 
ATOM   7344  O OG  . SER C 3 26  ? 91.425  122.120 136.347 1.00 182.90 ? 26  SER L OG  1 
ATOM   7345  N N   . GLN C 3 27  ? 89.663  119.513 137.953 1.00 130.92 ? 27  GLN L N   1 
ATOM   7346  C CA  . GLN C 3 27  ? 89.360  118.105 137.747 1.00 131.87 ? 27  GLN L CA  1 
ATOM   7347  C C   . GLN C 3 27  ? 89.168  117.476 139.102 1.00 106.95 ? 27  GLN L C   1 
ATOM   7348  O O   . GLN C 3 27  ? 89.475  118.112 140.104 1.00 88.14  ? 27  GLN L O   1 
ATOM   7349  C CB  . GLN C 3 27  ? 90.490  117.267 137.154 1.00 152.77 ? 27  GLN L CB  1 
ATOM   7350  C CG  . GLN C 3 27  ? 90.963  117.649 135.767 1.00 182.35 ? 27  GLN L CG  1 
ATOM   7351  C CD  . GLN C 3 27  ? 92.138  116.755 135.423 1.00 240.32 ? 27  GLN L CD  1 
ATOM   7352  O OE1 . GLN C 3 27  ? 92.951  117.117 134.575 1.00 285.71 ? 27  GLN L OE1 1 
ATOM   7353  N NE2 . GLN C 3 27  ? 92.262  115.593 136.082 1.00 172.10 ? 27  GLN L NE2 1 
ATOM   7354  N N   . SER C 3 28  ? 88.662  116.242 139.090 1.00 123.61 ? 28  SER L N   1 
ATOM   7355  C CA  . SER C 3 28  ? 88.490  115.476 140.309 1.00 127.89 ? 28  SER L CA  1 
ATOM   7356  C C   . SER C 3 28  ? 89.859  115.058 140.821 1.00 108.93 ? 28  SER L C   1 
ATOM   7357  O O   . SER C 3 28  ? 90.761  114.730 140.048 1.00 128.43 ? 28  SER L O   1 
ATOM   7358  C CB  . SER C 3 28  ? 87.611  114.295 140.078 1.00 198.73 ? 28  SER L CB  1 
ATOM   7359  O OG  . SER C 3 28  ? 87.432  113.550 141.261 1.00 150.15 ? 28  SER L OG  1 
ATOM   7360  N N   . LEU C 3 29  ? 89.983  115.101 142.141 1.00 81.88  ? 29  LEU L N   1 
ATOM   7361  C CA  . LEU C 3 29  ? 91.175  114.672 142.832 1.00 83.51  ? 29  LEU L CA  1 
ATOM   7362  C C   . LEU C 3 29  ? 90.780  113.555 143.778 1.00 110.85 ? 29  LEU L C   1 
ATOM   7363  O O   . LEU C 3 29  ? 91.435  113.380 144.784 1.00 95.12  ? 29  LEU L O   1 
ATOM   7364  C CB  . LEU C 3 29  ? 91.773  115.785 143.693 1.00 72.40  ? 29  LEU L CB  1 
ATOM   7365  C CG  . LEU C 3 29  ? 91.804  117.177 143.116 1.00 78.54  ? 29  LEU L CG  1 
ATOM   7366  C CD1 . LEU C 3 29  ? 92.325  118.165 144.186 1.00 74.28  ? 29  LEU L CD1 1 
ATOM   7367  C CD2 . LEU C 3 29  ? 92.610  117.223 141.835 1.00 95.83  ? 29  LEU L CD2 1 
ATOM   7368  N N   . LEU C 3 30  ? 89.735  112.804 143.452 1.00 129.15 ? 30  LEU L N   1 
ATOM   7369  C CA  . LEU C 3 30  ? 89.536  111.484 144.006 1.00 132.20 ? 30  LEU L CA  1 
ATOM   7370  C C   . LEU C 3 30  ? 90.248  110.466 143.093 1.00 173.68 ? 30  LEU L C   1 
ATOM   7371  O O   . LEU C 3 30  ? 90.049  110.427 141.853 1.00 87.80  ? 30  LEU L O   1 
ATOM   7372  C CB  . LEU C 3 30  ? 88.023  111.270 144.073 1.00 140.92 ? 30  LEU L CB  1 
ATOM   7373  C CG  . LEU C 3 30  ? 87.568  109.910 144.552 1.00 178.12 ? 30  LEU L CG  1 
ATOM   7374  C CD1 . LEU C 3 30  ? 88.186  109.587 145.898 1.00 142.38 ? 30  LEU L CD1 1 
ATOM   7375  C CD2 . LEU C 3 30  ? 86.049  109.886 144.614 1.00 217.18 ? 30  LEU L CD2 1 
ATOM   7376  N N   . ASN C 3 31  ? 91.095  109.631 143.728 1.00 183.59 ? 31  ASN L N   1 
ATOM   7377  C CA  . ASN C 3 31  ? 91.748  108.490 143.085 1.00 154.63 ? 31  ASN L CA  1 
ATOM   7378  C C   . ASN C 3 31  ? 90.832  107.285 143.273 1.00 155.04 ? 31  ASN L C   1 
ATOM   7379  O O   . ASN C 3 31  ? 90.777  106.724 144.373 1.00 146.64 ? 31  ASN L O   1 
ATOM   7380  C CB  . ASN C 3 31  ? 93.160  108.287 143.645 1.00 158.56 ? 31  ASN L CB  1 
ATOM   7381  C CG  . ASN C 3 31  ? 93.885  107.059 143.148 1.00 171.13 ? 31  ASN L CG  1 
ATOM   7382  O OD1 . ASN C 3 31  ? 93.526  106.434 142.140 1.00 255.76 ? 31  ASN L OD1 1 
ATOM   7383  N ND2 . ASN C 3 31  ? 94.904  106.670 143.893 1.00 188.70 ? 31  ASN L ND2 1 
ATOM   7384  N N   . ASN C 3 32  ? 90.121  106.896 142.191 1.00 158.26 ? 32  ASN L N   1 
ATOM   7385  C CA  . ASN C 3 32  ? 89.097  105.843 142.226 1.00 135.37 ? 32  ASN L CA  1 
ATOM   7386  C C   . ASN C 3 32  ? 89.593  104.539 142.841 1.00 151.85 ? 32  ASN L C   1 
ATOM   7387  O O   . ASN C 3 32  ? 88.876  103.922 143.617 1.00 178.75 ? 32  ASN L O   1 
ATOM   7388  C CB  . ASN C 3 32  ? 88.560  105.546 140.830 1.00 151.60 ? 32  ASN L CB  1 
ATOM   7389  C CG  . ASN C 3 32  ? 87.823  106.743 140.265 1.00 267.45 ? 32  ASN L CG  1 
ATOM   7390  O OD1 . ASN C 3 32  ? 86.977  107.313 140.951 1.00 275.39 ? 32  ASN L OD1 1 
ATOM   7391  N ND2 . ASN C 3 32  ? 88.140  107.140 139.038 1.00 339.73 ? 32  ASN L ND2 1 
ATOM   7392  N N   . ASN C 3 33  ? 90.826  104.152 142.490 1.00 204.86 ? 33  ASN L N   1 
ATOM   7393  C CA  . ASN C 3 33  ? 91.446  102.900 142.914 1.00 166.21 ? 33  ASN L CA  1 
ATOM   7394  C C   . ASN C 3 33  ? 91.646  102.815 144.434 1.00 131.51 ? 33  ASN L C   1 
ATOM   7395  O O   . ASN C 3 33  ? 91.830  101.717 144.944 1.00 149.71 ? 33  ASN L O   1 
ATOM   7396  C CB  . ASN C 3 33  ? 92.825  102.689 142.261 1.00 222.28 ? 33  ASN L CB  1 
ATOM   7397  C CG  . ASN C 3 33  ? 92.864  102.945 140.766 1.00 248.36 ? 33  ASN L CG  1 
ATOM   7398  O OD1 . ASN C 3 33  ? 92.272  102.204 139.980 1.00 234.07 ? 33  ASN L OD1 1 
ATOM   7399  N ND2 . ASN C 3 33  ? 93.561  103.998 140.370 1.00 268.08 ? 33  ASN L ND2 1 
ATOM   7400  N N   . ASN C 3 34  ? 91.637  103.959 145.150 1.00 178.68 ? 34  ASN L N   1 
ATOM   7401  C CA  . ASN C 3 34  ? 92.145  104.042 146.519 1.00 180.32 ? 34  ASN L CA  1 
ATOM   7402  C C   . ASN C 3 34  ? 91.223  104.795 147.480 1.00 210.53 ? 34  ASN L C   1 
ATOM   7403  O O   . ASN C 3 34  ? 91.443  104.665 148.698 1.00 144.35 ? 34  ASN L O   1 
ATOM   7404  C CB  . ASN C 3 34  ? 93.535  104.683 146.540 1.00 143.30 ? 34  ASN L CB  1 
ATOM   7405  C CG  . ASN C 3 34  ? 94.297  104.339 147.793 1.00 237.07 ? 34  ASN L CG  1 
ATOM   7406  O OD1 . ASN C 3 34  ? 94.774  105.224 148.493 1.00 301.96 ? 34  ASN L OD1 1 
ATOM   7407  N ND2 . ASN C 3 34  ? 94.432  103.057 148.101 1.00 338.07 ? 34  ASN L ND2 1 
ATOM   7408  N N   . GLN C 3 35  ? 90.232  105.551 146.946 1.00 218.59 ? 35  GLN L N   1 
ATOM   7409  C CA  . GLN C 3 35  ? 89.195  106.208 147.722 1.00 203.66 ? 35  GLN L CA  1 
ATOM   7410  C C   . GLN C 3 35  ? 89.831  107.156 148.730 1.00 199.39 ? 35  GLN L C   1 
ATOM   7411  O O   . GLN C 3 35  ? 89.461  107.170 149.910 1.00 257.69 ? 35  GLN L O   1 
ATOM   7412  C CB  . GLN C 3 35  ? 88.275  105.172 148.368 1.00 276.10 ? 35  GLN L CB  1 
ATOM   7413  C CG  . GLN C 3 35  ? 87.515  104.331 147.359 1.00 259.38 ? 35  GLN L CG  1 
ATOM   7414  C CD  . GLN C 3 35  ? 86.590  105.169 146.505 1.00 260.63 ? 35  GLN L CD  1 
ATOM   7415  O OE1 . GLN C 3 35  ? 85.854  106.022 147.000 1.00 283.65 ? 35  GLN L OE1 1 
ATOM   7416  N NE2 . GLN C 3 35  ? 86.612  104.933 145.204 1.00 253.56 ? 35  GLN L NE2 1 
ATOM   7417  N N   . LYS C 3 36  ? 90.792  107.953 148.235 1.00 167.49 ? 36  LYS L N   1 
ATOM   7418  C CA  . LYS C 3 36  ? 91.167  109.169 148.937 1.00 148.22 ? 36  LYS L CA  1 
ATOM   7419  C C   . LYS C 3 36  ? 91.476  110.275 147.940 1.00 137.27 ? 36  LYS L C   1 
ATOM   7420  O O   . LYS C 3 36  ? 91.713  110.023 146.750 1.00 93.12  ? 36  LYS L O   1 
ATOM   7421  C CB  . LYS C 3 36  ? 92.302  108.937 149.928 1.00 140.58 ? 36  LYS L CB  1 
ATOM   7422  C CG  . LYS C 3 36  ? 93.646  108.615 149.318 1.00 151.72 ? 36  LYS L CG  1 
ATOM   7423  C CD  . LYS C 3 36  ? 94.614  108.154 150.380 1.00 152.45 ? 36  LYS L CD  1 
ATOM   7424  C CE  . LYS C 3 36  ? 95.885  107.607 149.809 1.00 177.34 ? 36  LYS L CE  1 
ATOM   7425  N NZ  . LYS C 3 36  ? 96.485  106.560 150.668 1.00 269.69 ? 36  LYS L NZ  1 
ATOM   7426  N N   . ASN C 3 37  ? 91.432  111.492 148.514 1.00 131.22 ? 37  ASN L N   1 
ATOM   7427  C CA  . ASN C 3 37  ? 91.350  112.719 147.749 1.00 104.02 ? 37  ASN L CA  1 
ATOM   7428  C C   . ASN C 3 37  ? 92.652  113.440 147.971 1.00 92.22  ? 37  ASN L C   1 
ATOM   7429  O O   . ASN C 3 37  ? 93.027  113.699 149.109 1.00 74.24  ? 37  ASN L O   1 
ATOM   7430  C CB  . ASN C 3 37  ? 90.218  113.618 148.205 1.00 127.16 ? 37  ASN L CB  1 
ATOM   7431  C CG  . ASN C 3 37  ? 88.840  113.082 147.908 1.00 185.72 ? 37  ASN L CG  1 
ATOM   7432  O OD1 . ASN C 3 37  ? 88.315  113.398 146.844 1.00 165.38 ? 37  ASN L OD1 1 
ATOM   7433  N ND2 . ASN C 3 37  ? 88.264  112.301 148.816 1.00 201.09 ? 37  ASN L ND2 1 
ATOM   7434  N N   . TYR C 3 38  ? 93.333  113.753 146.880 1.00 96.88  ? 38  TYR L N   1 
ATOM   7435  C CA  . TYR C 3 38  ? 94.679  114.299 146.947 1.00 78.62  ? 38  TYR L CA  1 
ATOM   7436  C C   . TYR C 3 38  ? 94.647  115.808 146.997 1.00 66.23  ? 38  TYR L C   1 
ATOM   7437  O O   . TYR C 3 38  ? 94.511  116.424 145.946 1.00 54.86  ? 38  TYR L O   1 
ATOM   7438  C CB  . TYR C 3 38  ? 95.329  113.746 145.687 1.00 82.59  ? 38  TYR L CB  1 
ATOM   7439  C CG  . TYR C 3 38  ? 95.690  112.270 145.706 1.00 71.23  ? 38  TYR L CG  1 
ATOM   7440  C CD1 . TYR C 3 38  ? 95.717  111.516 146.850 1.00 86.83  ? 38  TYR L CD1 1 
ATOM   7441  C CD2 . TYR C 3 38  ? 96.071  111.647 144.571 1.00 80.48  ? 38  TYR L CD2 1 
ATOM   7442  C CE1 . TYR C 3 38  ? 96.092  110.183 146.855 1.00 121.08 ? 38  TYR L CE1 1 
ATOM   7443  C CE2 . TYR C 3 38  ? 96.453  110.328 144.540 1.00 114.04 ? 38  TYR L CE2 1 
ATOM   7444  C CZ  . TYR C 3 38  ? 96.457  109.572 145.687 1.00 153.50 ? 38  TYR L CZ  1 
ATOM   7445  O OH  . TYR C 3 38  ? 96.803  108.249 145.658 1.00 250.53 ? 38  TYR L OH  1 
ATOM   7446  N N   . LEU C 3 39  ? 94.735  116.364 148.207 1.00 67.14  ? 39  LEU L N   1 
ATOM   7447  C CA  . LEU C 3 39  ? 94.814  117.809 148.392 1.00 75.21  ? 39  LEU L CA  1 
ATOM   7448  C C   . LEU C 3 39  ? 95.489  118.170 149.687 1.00 75.91  ? 39  LEU L C   1 
ATOM   7449  O O   . LEU C 3 39  ? 95.398  117.388 150.627 1.00 71.64  ? 39  LEU L O   1 
ATOM   7450  C CB  . LEU C 3 39  ? 93.456  118.411 148.587 1.00 63.49  ? 39  LEU L CB  1 
ATOM   7451  C CG  . LEU C 3 39  ? 93.444  119.876 148.346 1.00 64.37  ? 39  LEU L CG  1 
ATOM   7452  C CD1 . LEU C 3 39  ? 93.323  120.026 146.785 1.00 76.20  ? 39  LEU L CD1 1 
ATOM   7453  C CD2 . LEU C 3 39  ? 92.359  120.477 149.246 1.00 96.64  ? 39  LEU L CD2 1 
ATOM   7454  N N   . ALA C 3 40  ? 96.126  119.343 149.695 1.00 68.40  ? 40  ALA L N   1 
ATOM   7455  C CA  . ALA C 3 40  ? 96.781  119.851 150.872 1.00 62.45  ? 40  ALA L CA  1 
ATOM   7456  C C   . ALA C 3 40  ? 96.508  121.327 151.036 1.00 66.44  ? 40  ALA L C   1 
ATOM   7457  O O   . ALA C 3 40  ? 96.181  121.998 150.067 1.00 73.50  ? 40  ALA L O   1 
ATOM   7458  C CB  . ALA C 3 40  ? 98.257  119.656 150.740 1.00 57.23  ? 40  ALA L CB  1 
ATOM   7459  N N   . TRP C 3 41  ? 96.722  121.731 152.288 1.00 57.04  ? 41  TRP L N   1 
ATOM   7460  C CA  . TRP C 3 41  ? 96.577  123.061 152.791 1.00 66.21  ? 41  TRP L CA  1 
ATOM   7461  C C   . TRP C 3 41  ? 97.919  123.532 153.337 1.00 63.77  ? 41  TRP L C   1 
ATOM   7462  O O   . TRP C 3 41  ? 98.437  122.890 154.233 1.00 96.84  ? 41  TRP L O   1 
ATOM   7463  C CB  . TRP C 3 41  ? 95.420  123.047 153.836 1.00 77.60  ? 41  TRP L CB  1 
ATOM   7464  C CG  . TRP C 3 41  ? 94.100  123.085 153.110 1.00 76.76  ? 41  TRP L CG  1 
ATOM   7465  C CD1 . TRP C 3 41  ? 93.338  122.015 152.969 1.00 70.41  ? 41  TRP L CD1 1 
ATOM   7466  C CD2 . TRP C 3 41  ? 93.434  124.150 152.397 1.00 83.69  ? 41  TRP L CD2 1 
ATOM   7467  N NE1 . TRP C 3 41  ? 92.261  122.299 152.208 1.00 82.01  ? 41  TRP L NE1 1 
ATOM   7468  C CE2 . TRP C 3 41  ? 92.287  123.606 151.856 1.00 75.20  ? 41  TRP L CE2 1 
ATOM   7469  C CE3 . TRP C 3 41  ? 93.691  125.501 152.173 1.00 99.05  ? 41  TRP L CE3 1 
ATOM   7470  C CZ2 . TRP C 3 41  ? 91.386  124.340 151.112 1.00 88.11  ? 41  TRP L CZ2 1 
ATOM   7471  C CZ3 . TRP C 3 41  ? 92.802  126.246 151.445 1.00 122.63 ? 41  TRP L CZ3 1 
ATOM   7472  C CH2 . TRP C 3 41  ? 91.659  125.663 150.912 1.00 130.05 ? 41  TRP L CH2 1 
ATOM   7473  N N   . TYR C 3 42  ? 98.459  124.677 152.869 1.00 62.68  ? 42  TYR L N   1 
ATOM   7474  C CA  . TYR C 3 42  ? 99.601  125.277 153.545 1.00 68.40  ? 42  TYR L CA  1 
ATOM   7475  C C   . TYR C 3 42  ? 99.249  126.615 154.127 1.00 62.58  ? 42  TYR L C   1 
ATOM   7476  O O   . TYR C 3 42  ? 98.508  127.325 153.525 1.00 64.67  ? 42  TYR L O   1 
ATOM   7477  C CB  . TYR C 3 42  ? 100.766 125.509 152.630 1.00 60.63  ? 42  TYR L CB  1 
ATOM   7478  C CG  . TYR C 3 42  ? 101.229 124.231 151.927 1.00 69.25  ? 42  TYR L CG  1 
ATOM   7479  C CD1 . TYR C 3 42  ? 100.666 123.808 150.754 1.00 61.66  ? 42  TYR L CD1 1 
ATOM   7480  C CD2 . TYR C 3 42  ? 102.264 123.463 152.442 1.00 66.46  ? 42  TYR L CD2 1 
ATOM   7481  C CE1 . TYR C 3 42  ? 101.102 122.673 150.119 1.00 69.16  ? 42  TYR L CE1 1 
ATOM   7482  C CE2 . TYR C 3 42  ? 102.723 122.339 151.813 1.00 62.66  ? 42  TYR L CE2 1 
ATOM   7483  C CZ  . TYR C 3 42  ? 102.131 121.930 150.637 1.00 72.32  ? 42  TYR L CZ  1 
ATOM   7484  O OH  . TYR C 3 42  ? 102.535 120.797 149.965 1.00 65.38  ? 42  TYR L OH  1 
ATOM   7485  N N   . GLN C 3 43  ? 99.776  126.885 155.302 1.00 81.81  ? 43  GLN L N   1 
ATOM   7486  C CA  . GLN C 3 43  ? 99.686  128.158 155.985 1.00 88.55  ? 43  GLN L CA  1 
ATOM   7487  C C   . GLN C 3 43  ? 100.996 128.866 155.682 1.00 79.11  ? 43  GLN L C   1 
ATOM   7488  O O   . GLN C 3 43  ? 102.042 128.271 155.757 1.00 113.64 ? 43  GLN L O   1 
ATOM   7489  C CB  . GLN C 3 43  ? 99.505  127.938 157.489 1.00 90.24  ? 43  GLN L CB  1 
ATOM   7490  C CG  . GLN C 3 43  ? 99.682  129.157 158.348 1.00 103.52 ? 43  GLN L CG  1 
ATOM   7491  C CD  . GLN C 3 43  ? 99.577  128.958 159.838 1.00 127.31 ? 43  GLN L CD  1 
ATOM   7492  O OE1 . GLN C 3 43  ? 99.652  129.901 160.607 1.00 217.77 ? 43  GLN L OE1 1 
ATOM   7493  N NE2 . GLN C 3 43  ? 99.408  127.749 160.289 1.00 182.10 ? 43  GLN L NE2 1 
ATOM   7494  N N   . GLN C 3 44  ? 100.960 130.146 155.347 1.00 82.39  ? 44  GLN L N   1 
ATOM   7495  C CA  . GLN C 3 44  ? 102.181 130.934 155.266 1.00 93.34  ? 44  GLN L CA  1 
ATOM   7496  C C   . GLN C 3 44  ? 101.965 132.229 156.026 1.00 80.29  ? 44  GLN L C   1 
ATOM   7497  O O   . GLN C 3 44  ? 101.294 133.166 155.516 1.00 82.43  ? 44  GLN L O   1 
ATOM   7498  C CB  . GLN C 3 44  ? 102.573 131.180 153.810 1.00 106.37 ? 44  GLN L CB  1 
ATOM   7499  C CG  . GLN C 3 44  ? 103.820 131.994 153.694 1.00 106.95 ? 44  GLN L CG  1 
ATOM   7500  C CD  . GLN C 3 44  ? 104.254 132.088 152.268 1.00 134.61 ? 44  GLN L CD  1 
ATOM   7501  O OE1 . GLN C 3 44  ? 103.447 132.122 151.340 1.00 163.12 ? 44  GLN L OE1 1 
ATOM   7502  N NE2 . GLN C 3 44  ? 105.565 132.146 152.108 1.00 176.52 ? 44  GLN L NE2 1 
ATOM   7503  N N   . LYS C 3 45  ? 102.535 132.256 157.242 1.00 70.83  ? 45  LYS L N   1 
ATOM   7504  C CA  . LYS C 3 45  ? 102.473 133.462 158.062 1.00 105.30 ? 45  LYS L CA  1 
ATOM   7505  C C   . LYS C 3 45  ? 103.372 134.512 157.416 1.00 112.51 ? 45  LYS L C   1 
ATOM   7506  O O   . LYS C 3 45  ? 104.292 134.163 156.673 1.00 167.46 ? 45  LYS L O   1 
ATOM   7507  C CB  . LYS C 3 45  ? 102.883 133.206 159.514 1.00 137.66 ? 45  LYS L CB  1 
ATOM   7508  C CG  . LYS C 3 45  ? 101.928 132.440 160.420 1.00 144.67 ? 45  LYS L CG  1 
ATOM   7509  C CD  . LYS C 3 45  ? 102.545 132.253 161.814 1.00 220.43 ? 45  LYS L CD  1 
ATOM   7510  C CE  . LYS C 3 45  ? 102.218 130.955 162.532 1.00 280.31 ? 45  LYS L CE  1 
ATOM   7511  N NZ  . LYS C 3 45  ? 100.776 130.840 162.887 1.00 349.38 ? 45  LYS L NZ  1 
ATOM   7512  N N   . PRO C 3 46  ? 103.139 135.812 157.658 1.00 132.02 ? 46  PRO L N   1 
ATOM   7513  C CA  . PRO C 3 46  ? 103.903 136.840 156.973 1.00 172.65 ? 46  PRO L CA  1 
ATOM   7514  C C   . PRO C 3 46  ? 105.363 136.725 157.399 1.00 160.34 ? 46  PRO L C   1 
ATOM   7515  O O   . PRO C 3 46  ? 105.652 136.667 158.595 1.00 142.13 ? 46  PRO L O   1 
ATOM   7516  C CB  . PRO C 3 46  ? 103.224 138.136 157.433 1.00 241.36 ? 46  PRO L CB  1 
ATOM   7517  C CG  . PRO C 3 46  ? 102.660 137.786 158.788 1.00 246.46 ? 46  PRO L CG  1 
ATOM   7518  C CD  . PRO C 3 46  ? 102.150 136.379 158.586 1.00 200.28 ? 46  PRO L CD  1 
ATOM   7519  N N   . GLY C 3 47  ? 106.249 136.676 156.385 1.00 196.20 ? 47  GLY L N   1 
ATOM   7520  C CA  . GLY C 3 47  ? 107.698 136.684 156.540 1.00 214.65 ? 47  GLY L CA  1 
ATOM   7521  C C   . GLY C 3 47  ? 108.314 135.316 156.849 1.00 162.12 ? 47  GLY L C   1 
ATOM   7522  O O   . GLY C 3 47  ? 109.455 135.247 157.310 1.00 189.60 ? 47  GLY L O   1 
ATOM   7523  N N   . GLN C 3 48  ? 107.567 134.230 156.606 1.00 139.73 ? 48  GLN L N   1 
ATOM   7524  C CA  . GLN C 3 48  ? 108.042 132.867 156.816 1.00 148.29 ? 48  GLN L CA  1 
ATOM   7525  C C   . GLN C 3 48  ? 107.725 131.971 155.603 1.00 135.31 ? 48  GLN L C   1 
ATOM   7526  O O   . GLN C 3 48  ? 107.065 132.369 154.644 1.00 200.92 ? 48  GLN L O   1 
ATOM   7527  C CB  . GLN C 3 48  ? 107.426 132.270 158.083 1.00 135.77 ? 48  GLN L CB  1 
ATOM   7528  C CG  . GLN C 3 48  ? 107.518 133.133 159.313 1.00 143.96 ? 48  GLN L CG  1 
ATOM   7529  C CD  . GLN C 3 48  ? 106.771 132.535 160.483 1.00 211.67 ? 48  GLN L CD  1 
ATOM   7530  O OE1 . GLN C 3 48  ? 106.396 131.362 160.484 1.00 230.28 ? 48  GLN L OE1 1 
ATOM   7531  N NE2 . GLN C 3 48  ? 106.557 133.349 161.507 1.00 260.77 ? 48  GLN L NE2 1 
ATOM   7532  N N   . SER C 3 49  ? 108.252 130.748 155.682 1.00 115.72 ? 49  SER L N   1 
ATOM   7533  C CA  . SER C 3 49  ? 108.112 129.693 154.702 1.00 103.80 ? 49  SER L CA  1 
ATOM   7534  C C   . SER C 3 49  ? 106.734 129.107 154.767 1.00 89.58  ? 49  SER L C   1 
ATOM   7535  O O   . SER C 3 49  ? 106.074 129.247 155.789 1.00 133.83 ? 49  SER L O   1 
ATOM   7536  C CB  . SER C 3 49  ? 109.128 128.599 154.967 1.00 166.45 ? 49  SER L CB  1 
ATOM   7537  O OG  . SER C 3 49  ? 109.077 128.116 156.316 1.00 186.98 ? 49  SER L OG  1 
ATOM   7538  N N   . PRO C 3 50  ? 106.243 128.401 153.721 1.00 82.32  ? 50  PRO L N   1 
ATOM   7539  C CA  . PRO C 3 50  ? 105.000 127.651 153.851 1.00 79.68  ? 50  PRO L CA  1 
ATOM   7540  C C   . PRO C 3 50  ? 105.156 126.527 154.881 1.00 77.67  ? 50  PRO L C   1 
ATOM   7541  O O   . PRO C 3 50  ? 106.220 125.929 154.944 1.00 74.29  ? 50  PRO L O   1 
ATOM   7542  C CB  . PRO C 3 50  ? 104.784 127.129 152.453 1.00 72.23  ? 50  PRO L CB  1 
ATOM   7543  C CG  . PRO C 3 50  ? 105.464 128.122 151.649 1.00 73.90  ? 50  PRO L CG  1 
ATOM   7544  C CD  . PRO C 3 50  ? 106.780 128.294 152.371 1.00 75.98  ? 50  PRO L CD  1 
ATOM   7545  N N   . LYS C 3 51  ? 104.084 126.258 155.670 1.00 81.28  ? 51  LYS L N   1 
ATOM   7546  C CA  . LYS C 3 51  ? 104.002 125.154 156.627 1.00 93.45  ? 51  LYS L CA  1 
ATOM   7547  C C   . LYS C 3 51  ? 102.873 124.263 156.135 1.00 89.83  ? 51  LYS L C   1 
ATOM   7548  O O   . LYS C 3 51  ? 101.808 124.784 155.809 1.00 69.63  ? 51  LYS L O   1 
ATOM   7549  C CB  . LYS C 3 51  ? 103.721 125.605 158.067 1.00 121.93 ? 51  LYS L CB  1 
ATOM   7550  C CG  . LYS C 3 51  ? 103.518 124.468 159.066 1.00 160.52 ? 51  LYS L CG  1 
ATOM   7551  C CD  . LYS C 3 51  ? 103.201 124.977 160.476 1.00 195.28 ? 51  LYS L CD  1 
ATOM   7552  C CE  . LYS C 3 51  ? 103.125 123.854 161.495 1.00 243.84 ? 51  LYS L CE  1 
ATOM   7553  N NZ  . LYS C 3 51  ? 102.470 124.235 162.777 1.00 244.35 ? 51  LYS L NZ  1 
ATOM   7554  N N   . LEU C 3 52  ? 103.091 122.938 156.086 1.00 88.56  ? 52  LEU L N   1 
ATOM   7555  C CA  . LEU C 3 52  ? 102.044 122.039 155.621 1.00 84.65  ? 52  LEU L CA  1 
ATOM   7556  C C   . LEU C 3 52  ? 101.063 121.783 156.759 1.00 84.20  ? 52  LEU L C   1 
ATOM   7557  O O   . LEU C 3 52  ? 101.541 121.499 157.848 1.00 96.09  ? 52  LEU L O   1 
ATOM   7558  C CB  . LEU C 3 52  ? 102.758 120.781 155.182 1.00 74.75  ? 52  LEU L CB  1 
ATOM   7559  C CG  . LEU C 3 52  ? 101.923 119.574 154.793 1.00 72.65  ? 52  LEU L CG  1 
ATOM   7560  C CD1 . LEU C 3 52  ? 100.961 119.857 153.696 1.00 70.46  ? 52  LEU L CD1 1 
ATOM   7561  C CD2 . LEU C 3 52  ? 102.902 118.525 154.291 1.00 99.85  ? 52  LEU L CD2 1 
ATOM   7562  N N   . LEU C 3 53  ? 99.743  121.916 156.506 1.00 69.41  ? 53  LEU L N   1 
ATOM   7563  C CA  . LEU C 3 53  ? 98.712  121.671 157.506 1.00 92.56  ? 53  LEU L CA  1 
ATOM   7564  C C   . LEU C 3 53  ? 98.103  120.313 157.359 1.00 79.10  ? 53  LEU L C   1 
ATOM   7565  O O   . LEU C 3 53  ? 98.265  119.472 158.260 1.00 113.47 ? 53  LEU L O   1 
ATOM   7566  C CB  . LEU C 3 53  ? 97.558  122.664 157.407 1.00 78.99  ? 53  LEU L CB  1 
ATOM   7567  C CG  . LEU C 3 53  ? 98.009  124.050 157.762 1.00 72.92  ? 53  LEU L CG  1 
ATOM   7568  C CD1 . LEU C 3 53  ? 96.857  124.986 157.589 1.00 95.11  ? 53  LEU L CD1 1 
ATOM   7569  C CD2 . LEU C 3 53  ? 98.503  124.023 159.191 1.00 64.51  ? 53  LEU L CD2 1 
ATOM   7570  N N   . VAL C 3 54  ? 97.364  120.183 156.262 1.00 58.95  ? 54  VAL L N   1 
ATOM   7571  C CA  . VAL C 3 54  ? 96.775  118.889 156.020 1.00 98.52  ? 54  VAL L CA  1 
ATOM   7572  C C   . VAL C 3 54  ? 97.070  118.418 154.605 1.00 73.34  ? 54  VAL L C   1 
ATOM   7573  O O   . VAL C 3 54  ? 97.290  119.192 153.731 1.00 78.95  ? 54  VAL L O   1 
ATOM   7574  C CB  . VAL C 3 54  ? 95.288  118.950 156.338 1.00 87.57  ? 54  VAL L CB  1 
ATOM   7575  C CG1 . VAL C 3 54  ? 95.021  119.578 157.683 1.00 131.39 ? 54  VAL L CG1 1 
ATOM   7576  C CG2 . VAL C 3 54  ? 94.620  119.775 155.355 1.00 73.08  ? 54  VAL L CG2 1 
ATOM   7577  N N   . TYR C 3 55  ? 97.064  117.133 154.431 1.00 63.78  ? 55  TYR L N   1 
ATOM   7578  C CA  . TYR C 3 55  ? 97.212  116.570 153.143 1.00 64.35  ? 55  TYR L CA  1 
ATOM   7579  C C   . TYR C 3 55  ? 96.300  115.351 153.026 1.00 80.58  ? 55  TYR L C   1 
ATOM   7580  O O   . TYR C 3 55  ? 95.700  114.930 154.003 1.00 122.73 ? 55  TYR L O   1 
ATOM   7581  C CB  . TYR C 3 55  ? 98.705  116.267 153.085 1.00 74.98  ? 55  TYR L CB  1 
ATOM   7582  C CG  . TYR C 3 55  ? 99.309  115.205 153.969 1.00 81.89  ? 55  TYR L CG  1 
ATOM   7583  C CD1 . TYR C 3 55  ? 99.283  113.866 153.646 1.00 85.14  ? 55  TYR L CD1 1 
ATOM   7584  C CD2 . TYR C 3 55  ? 99.951  115.591 155.123 1.00 103.58 ? 55  TYR L CD2 1 
ATOM   7585  C CE1 . TYR C 3 55  ? 99.880  112.960 154.526 1.00 144.75 ? 55  TYR L CE1 1 
ATOM   7586  C CE2 . TYR C 3 55  ? 100.577 114.692 155.971 1.00 146.56 ? 55  TYR L CE2 1 
ATOM   7587  C CZ  . TYR C 3 55  ? 100.535 113.357 155.684 1.00 128.76 ? 55  TYR L CZ  1 
ATOM   7588  O OH  . TYR C 3 55  ? 101.170 112.536 156.574 1.00 150.97 ? 55  TYR L OH  1 
ATOM   7589  N N   . PHE C 3 56  ? 96.213  114.766 151.834 1.00 80.34  ? 56  PHE L N   1 
ATOM   7590  C CA  . PHE C 3 56  ? 95.161  113.856 151.476 1.00 81.78  ? 56  PHE L CA  1 
ATOM   7591  C C   . PHE C 3 56  ? 93.801  114.323 151.968 1.00 102.35 ? 56  PHE L C   1 
ATOM   7592  O O   . PHE C 3 56  ? 93.033  113.529 152.526 1.00 110.23 ? 56  PHE L O   1 
ATOM   7593  C CB  . PHE C 3 56  ? 95.563  112.505 152.038 1.00 115.96 ? 56  PHE L CB  1 
ATOM   7594  C CG  . PHE C 3 56  ? 96.713  111.767 151.384 1.00 100.07 ? 56  PHE L CG  1 
ATOM   7595  C CD1 . PHE C 3 56  ? 96.901  111.741 150.047 1.00 59.88  ? 56  PHE L CD1 1 
ATOM   7596  C CD2 . PHE C 3 56  ? 97.543  111.004 152.151 1.00 164.10 ? 56  PHE L CD2 1 
ATOM   7597  C CE1 . PHE C 3 56  ? 97.906  111.037 149.489 1.00 95.58  ? 56  PHE L CE1 1 
ATOM   7598  C CE2 . PHE C 3 56  ? 98.569  110.282 151.598 1.00 149.94 ? 56  PHE L CE2 1 
ATOM   7599  C CZ  . PHE C 3 56  ? 98.748  110.308 150.264 1.00 151.97 ? 56  PHE L CZ  1 
ATOM   7600  N N   . THR C 3 57  ? 93.566  115.632 151.772 1.00 105.67 ? 57  THR L N   1 
ATOM   7601  C CA  . THR C 3 57  ? 92.399  116.395 152.206 1.00 107.40 ? 57  THR L CA  1 
ATOM   7602  C C   . THR C 3 57  ? 92.155  116.491 153.712 1.00 85.23  ? 57  THR L C   1 
ATOM   7603  O O   . THR C 3 57  ? 91.552  117.470 154.095 1.00 120.28 ? 57  THR L O   1 
ATOM   7604  C CB  . THR C 3 57  ? 91.143  115.845 151.589 1.00 119.45 ? 57  THR L CB  1 
ATOM   7605  O OG1 . THR C 3 57  ? 91.454  115.771 150.206 1.00 99.90  ? 57  THR L OG1 1 
ATOM   7606  C CG2 . THR C 3 57  ? 89.981  116.760 151.835 1.00 160.32 ? 57  THR L CG2 1 
ATOM   7607  N N   . SER C 3 58  ? 92.582  115.564 154.551 1.00 85.69  ? 58  SER L N   1 
ATOM   7608  C CA  . SER C 3 58  ? 92.122  115.572 155.913 1.00 122.11 ? 58  SER L CA  1 
ATOM   7609  C C   . SER C 3 58  ? 93.202  115.265 156.945 1.00 120.96 ? 58  SER L C   1 
ATOM   7610  O O   . SER C 3 58  ? 93.052  115.686 158.088 1.00 184.74 ? 58  SER L O   1 
ATOM   7611  C CB  . SER C 3 58  ? 90.955  114.632 156.004 1.00 141.50 ? 58  SER L CB  1 
ATOM   7612  O OG  . SER C 3 58  ? 91.382  113.307 155.801 1.00 145.53 ? 58  SER L OG  1 
ATOM   7613  N N   . THR C 3 59  ? 94.234  114.536 156.557 1.00 96.08  ? 59  THR L N   1 
ATOM   7614  C CA  . THR C 3 59  ? 95.248  114.059 157.460 1.00 114.33 ? 59  THR L CA  1 
ATOM   7615  C C   . THR C 3 59  ? 96.094  115.244 157.915 1.00 117.59 ? 59  THR L C   1 
ATOM   7616  O O   . THR C 3 59  ? 96.775  115.867 157.108 1.00 167.02 ? 59  THR L O   1 
ATOM   7617  C CB  . THR C 3 59  ? 96.091  113.015 156.726 1.00 157.12 ? 59  THR L CB  1 
ATOM   7618  O OG1 . THR C 3 59  ? 95.218  111.892 156.586 1.00 152.80 ? 59  THR L OG1 1 
ATOM   7619  C CG2 . THR C 3 59  ? 97.392  112.646 157.406 1.00 165.49 ? 59  THR L CG2 1 
ATOM   7620  N N   . ARG C 3 60  ? 96.007  115.526 159.212 1.00 117.00 ? 60  ARG L N   1 
ATOM   7621  C CA  . ARG C 3 60  ? 96.819  116.536 159.871 1.00 109.08 ? 60  ARG L CA  1 
ATOM   7622  C C   . ARG C 3 60  ? 98.271  116.101 159.889 1.00 110.20 ? 60  ARG L C   1 
ATOM   7623  O O   . ARG C 3 60  ? 98.590  114.933 160.119 1.00 122.08 ? 60  ARG L O   1 
ATOM   7624  C CB  . ARG C 3 60  ? 96.335  116.784 161.309 1.00 165.96 ? 60  ARG L CB  1 
ATOM   7625  C CG  . ARG C 3 60  ? 95.301  117.892 161.372 1.00 205.14 ? 60  ARG L CG  1 
ATOM   7626  C CD  . ARG C 3 60  ? 95.113  118.450 162.762 1.00 170.02 ? 60  ARG L CD  1 
ATOM   7627  N NE  . ARG C 3 60  ? 94.395  117.519 163.582 1.00 172.71 ? 60  ARG L NE  1 
ATOM   7628  C CZ  . ARG C 3 60  ? 93.104  117.216 163.455 1.00 256.18 ? 60  ARG L CZ  1 
ATOM   7629  N NH1 . ARG C 3 60  ? 92.551  116.399 164.337 1.00 358.53 ? 60  ARG L NH1 1 
ATOM   7630  N NH2 . ARG C 3 60  ? 92.351  117.719 162.476 1.00 187.97 ? 60  ARG L NH2 1 
ATOM   7631  N N   . GLU C 3 61  ? 99.142  117.072 159.637 1.00 120.07 ? 61  GLU L N   1 
ATOM   7632  C CA  . GLU C 3 61  ? 100.579 116.848 159.759 1.00 139.24 ? 61  GLU L CA  1 
ATOM   7633  C C   . GLU C 3 61  ? 100.936 116.826 161.243 1.00 140.10 ? 61  GLU L C   1 
ATOM   7634  O O   . GLU C 3 61  ? 100.206 117.407 162.030 1.00 120.16 ? 61  GLU L O   1 
ATOM   7635  C CB  . GLU C 3 61  ? 101.289 117.909 158.897 1.00 122.25 ? 61  GLU L CB  1 
ATOM   7636  C CG  . GLU C 3 61  ? 102.797 117.951 158.968 1.00 172.21 ? 61  GLU L CG  1 
ATOM   7637  C CD  . GLU C 3 61  ? 103.617 116.711 158.663 1.00 211.09 ? 61  GLU L CD  1 
ATOM   7638  O OE1 . GLU C 3 61  ? 103.139 115.578 158.891 1.00 298.65 ? 61  GLU L OE1 1 
ATOM   7639  O OE2 . GLU C 3 61  ? 104.766 116.895 158.198 1.00 210.46 ? 61  GLU L OE2 1 
ATOM   7640  N N   . SER C 3 62  ? 102.045 116.167 161.622 1.00 184.99 ? 62  SER L N   1 
ATOM   7641  C CA  . SER C 3 62  ? 102.591 116.273 162.977 1.00 223.22 ? 62  SER L CA  1 
ATOM   7642  C C   . SER C 3 62  ? 102.966 117.721 163.328 1.00 184.43 ? 62  SER L C   1 
ATOM   7643  O O   . SER C 3 62  ? 103.519 118.447 162.501 1.00 221.26 ? 62  SER L O   1 
ATOM   7644  C CB  . SER C 3 62  ? 103.775 115.324 163.181 1.00 261.42 ? 62  SER L CB  1 
ATOM   7645  O OG  . SER C 3 62  ? 104.964 115.744 162.500 1.00 197.80 ? 62  SER L OG  1 
ATOM   7646  N N   . GLY C 3 63  ? 102.655 118.134 164.566 1.00 232.42 ? 63  GLY L N   1 
ATOM   7647  C CA  . GLY C 3 63  ? 102.902 119.492 165.026 1.00 246.14 ? 63  GLY L CA  1 
ATOM   7648  C C   . GLY C 3 63  ? 101.859 120.494 164.539 1.00 185.43 ? 63  GLY L C   1 
ATOM   7649  O O   . GLY C 3 63  ? 102.166 121.693 164.520 1.00 214.54 ? 63  GLY L O   1 
ATOM   7650  N N   . VAL C 3 64  ? 100.660 119.992 164.171 1.00 128.05 ? 64  VAL L N   1 
ATOM   7651  C CA  . VAL C 3 64  ? 99.572  120.844 163.726 1.00 177.83 ? 64  VAL L CA  1 
ATOM   7652  C C   . VAL C 3 64  ? 98.496  120.845 164.808 1.00 180.59 ? 64  VAL L C   1 
ATOM   7653  O O   . VAL C 3 64  ? 98.028  119.777 165.197 1.00 192.94 ? 64  VAL L O   1 
ATOM   7654  C CB  . VAL C 3 64  ? 99.033  120.439 162.337 1.00 157.26 ? 64  VAL L CB  1 
ATOM   7655  C CG1 . VAL C 3 64  ? 97.772  121.191 161.944 1.00 146.45 ? 64  VAL L CG1 1 
ATOM   7656  C CG2 . VAL C 3 64  ? 100.066 120.708 161.275 1.00 163.86 ? 64  VAL L CG2 1 
ATOM   7657  N N   . PRO C 3 65  ? 98.078  122.040 165.298 1.00 182.27 ? 65  PRO L N   1 
ATOM   7658  C CA  . PRO C 3 65  ? 96.936  122.149 166.200 1.00 218.23 ? 65  PRO L CA  1 
ATOM   7659  C C   . PRO C 3 65  ? 95.636  121.589 165.642 1.00 180.63 ? 65  PRO L C   1 
ATOM   7660  O O   . PRO C 3 65  ? 95.375  121.760 164.471 1.00 148.09 ? 65  PRO L O   1 
ATOM   7661  C CB  . PRO C 3 65  ? 96.761  123.657 166.337 1.00 248.54 ? 65  PRO L CB  1 
ATOM   7662  C CG  . PRO C 3 65  ? 98.132  124.226 166.111 1.00 262.08 ? 65  PRO L CG  1 
ATOM   7663  C CD  . PRO C 3 65  ? 98.676  123.358 165.011 1.00 212.80 ? 65  PRO L CD  1 
ATOM   7664  N N   . ASP C 3 66  ? 94.841  120.930 166.493 1.00 220.14 ? 66  ASP L N   1 
ATOM   7665  C CA  . ASP C 3 66  ? 93.709  120.138 166.036 1.00 241.82 ? 66  ASP L CA  1 
ATOM   7666  C C   . ASP C 3 66  ? 92.511  121.022 165.691 1.00 182.79 ? 66  ASP L C   1 
ATOM   7667  O O   . ASP C 3 66  ? 91.454  120.480 165.359 1.00 160.76 ? 66  ASP L O   1 
ATOM   7668  C CB  . ASP C 3 66  ? 93.382  119.062 167.074 1.00 308.64 ? 66  ASP L CB  1 
ATOM   7669  C CG  . ASP C 3 66  ? 94.507  118.051 167.215 1.00 351.91 ? 66  ASP L CG  1 
ATOM   7670  O OD1 . ASP C 3 66  ? 94.539  117.113 166.405 1.00 385.50 ? 66  ASP L OD1 1 
ATOM   7671  O OD2 . ASP C 3 66  ? 95.348  118.218 168.128 1.00 331.70 ? 66  ASP L OD2 1 
ATOM   7672  N N   . ARG C 3 67  ? 92.667  122.357 165.761 1.00 162.09 ? 67  ARG L N   1 
ATOM   7673  C CA  . ARG C 3 67  ? 91.651  123.265 165.247 1.00 221.19 ? 67  ARG L CA  1 
ATOM   7674  C C   . ARG C 3 67  ? 91.589  123.308 163.714 1.00 189.74 ? 67  ARG L C   1 
ATOM   7675  O O   . ARG C 3 67  ? 90.610  123.813 163.200 1.00 179.92 ? 67  ARG L O   1 
ATOM   7676  C CB  . ARG C 3 67  ? 91.865  124.668 165.819 1.00 249.65 ? 67  ARG L CB  1 
ATOM   7677  C CG  . ARG C 3 67  ? 93.154  125.357 165.410 1.00 221.15 ? 67  ARG L CG  1 
ATOM   7678  C CD  . ARG C 3 67  ? 93.163  126.729 166.053 1.00 207.61 ? 67  ARG L CD  1 
ATOM   7679  N NE  . ARG C 3 67  ? 94.350  127.515 165.779 1.00 139.78 ? 67  ARG L NE  1 
ATOM   7680  C CZ  . ARG C 3 67  ? 95.493  127.450 166.463 1.00 194.40 ? 67  ARG L CZ  1 
ATOM   7681  N NH1 . ARG C 3 67  ? 96.533  128.172 166.069 1.00 281.42 ? 67  ARG L NH1 1 
ATOM   7682  N NH2 . ARG C 3 67  ? 95.618  126.664 167.527 1.00 134.02 ? 67  ARG L NH2 1 
ATOM   7683  N N   . PHE C 3 68  ? 92.585  122.804 162.973 1.00 161.50 ? 68  PHE L N   1 
ATOM   7684  C CA  . PHE C 3 68  ? 92.505  122.721 161.513 1.00 153.26 ? 68  PHE L CA  1 
ATOM   7685  C C   . PHE C 3 68  ? 91.853  121.400 161.094 1.00 124.61 ? 68  PHE L C   1 
ATOM   7686  O O   . PHE C 3 68  ? 92.408  120.304 161.283 1.00 98.06  ? 68  PHE L O   1 
ATOM   7687  C CB  . PHE C 3 68  ? 93.885  122.863 160.857 1.00 150.68 ? 68  PHE L CB  1 
ATOM   7688  C CG  . PHE C 3 68  ? 94.566  124.160 161.160 1.00 113.36 ? 68  PHE L CG  1 
ATOM   7689  C CD1 . PHE C 3 68  ? 94.191  125.296 160.466 1.00 92.45  ? 68  PHE L CD1 1 
ATOM   7690  C CD2 . PHE C 3 68  ? 95.547  124.232 162.153 1.00 108.66 ? 68  PHE L CD2 1 
ATOM   7691  C CE1 . PHE C 3 68  ? 94.822  126.502 160.756 1.00 135.17 ? 68  PHE L CE1 1 
ATOM   7692  C CE2 . PHE C 3 68  ? 96.157  125.440 162.449 1.00 128.29 ? 68  PHE L CE2 1 
ATOM   7693  C CZ  . PHE C 3 68  ? 95.795  126.581 161.748 1.00 112.95 ? 68  PHE L CZ  1 
ATOM   7694  N N   . ILE C 3 69  ? 90.649  121.527 160.529 1.00 139.19 ? 69  ILE L N   1 
ATOM   7695  C CA  . ILE C 3 69  ? 89.883  120.391 160.073 1.00 169.65 ? 69  ILE L CA  1 
ATOM   7696  C C   . ILE C 3 69  ? 89.698  120.577 158.579 1.00 150.10 ? 69  ILE L C   1 
ATOM   7697  O O   . ILE C 3 69  ? 89.116  121.594 158.151 1.00 162.77 ? 69  ILE L O   1 
ATOM   7698  C CB  . ILE C 3 69  ? 88.558  120.271 160.854 1.00 177.47 ? 69  ILE L CB  1 
ATOM   7699  C CG1 . ILE C 3 69  ? 88.859  119.980 162.331 1.00 212.99 ? 69  ILE L CG1 1 
ATOM   7700  C CG2 . ILE C 3 69  ? 87.660  119.215 160.208 1.00 220.13 ? 69  ILE L CG2 1 
ATOM   7701  C CD1 . ILE C 3 69  ? 87.679  119.957 163.259 1.00 304.59 ? 69  ILE L CD1 1 
ATOM   7702  N N   . GLY C 3 70  ? 90.196  119.580 157.823 1.00 95.18  ? 70  GLY L N   1 
ATOM   7703  C CA  . GLY C 3 70  ? 90.031  119.631 156.377 1.00 122.44 ? 70  GLY L CA  1 
ATOM   7704  C C   . GLY C 3 70  ? 89.037  118.598 155.875 1.00 125.60 ? 70  GLY L C   1 
ATOM   7705  O O   . GLY C 3 70  ? 88.967  117.493 156.421 1.00 148.52 ? 70  GLY L O   1 
ATOM   7706  N N   . SER C 3 71  ? 88.288  118.967 154.835 1.00 125.45 ? 71  SER L N   1 
ATOM   7707  C CA  . SER C 3 71  ? 87.185  118.128 154.411 1.00 146.57 ? 71  SER L CA  1 
ATOM   7708  C C   . SER C 3 71  ? 86.794  118.455 152.983 1.00 129.36 ? 71  SER L C   1 
ATOM   7709  O O   . SER C 3 71  ? 87.195  119.488 152.447 1.00 126.61 ? 71  SER L O   1 
ATOM   7710  C CB  . SER C 3 71  ? 85.988  118.292 155.352 1.00 235.43 ? 71  SER L CB  1 
ATOM   7711  O OG  . SER C 3 71  ? 85.537  119.646 155.465 1.00 211.42 ? 71  SER L OG  1 
ATOM   7712  N N   . GLY C 3 72  ? 85.979  117.557 152.431 1.00 151.62 ? 72  GLY L N   1 
ATOM   7713  C CA  . GLY C 3 72  ? 85.470  117.664 151.080 1.00 187.66 ? 72  GLY L CA  1 
ATOM   7714  C C   . GLY C 3 72  ? 85.812  116.402 150.304 1.00 180.98 ? 72  GLY L C   1 
ATOM   7715  O O   . GLY C 3 72  ? 86.473  115.484 150.823 1.00 135.74 ? 72  GLY L O   1 
ATOM   7716  N N   . SER C 3 73  ? 85.329  116.387 149.054 1.00 148.06 ? 73  SER L N   1 
ATOM   7717  C CA  . SER C 3 73  ? 85.700  115.354 148.104 1.00 172.68 ? 73  SER L CA  1 
ATOM   7718  C C   . SER C 3 73  ? 85.442  115.845 146.693 1.00 132.97 ? 73  SER L C   1 
ATOM   7719  O O   . SER C 3 73  ? 84.730  116.806 146.512 1.00 127.90 ? 73  SER L O   1 
ATOM   7720  C CB  . SER C 3 73  ? 84.985  114.029 148.364 1.00 218.22 ? 73  SER L CB  1 
ATOM   7721  O OG  . SER C 3 73  ? 83.573  114.155 148.212 1.00 266.93 ? 73  SER L OG  1 
ATOM   7722  N N   . GLY C 3 74  ? 86.027  115.154 145.713 1.00 160.49 ? 74  GLY L N   1 
ATOM   7723  C CA  . GLY C 3 74  ? 85.757  115.413 144.310 1.00 168.93 ? 74  GLY L CA  1 
ATOM   7724  C C   . GLY C 3 74  ? 86.484  116.666 143.853 1.00 119.11 ? 74  GLY L C   1 
ATOM   7725  O O   . GLY C 3 74  ? 87.614  116.589 143.418 1.00 107.39 ? 74  GLY L O   1 
ATOM   7726  N N   . THR C 3 75  ? 85.804  117.807 143.966 1.00 127.97 ? 75  THR L N   1 
ATOM   7727  C CA  . THR C 3 75  ? 86.329  119.109 143.584 1.00 134.27 ? 75  THR L CA  1 
ATOM   7728  C C   . THR C 3 75  ? 86.014  120.210 144.614 1.00 127.74 ? 75  THR L C   1 
ATOM   7729  O O   . THR C 3 75  ? 86.651  121.242 144.569 1.00 153.95 ? 75  THR L O   1 
ATOM   7730  C CB  . THR C 3 75  ? 85.821  119.499 142.180 1.00 141.65 ? 75  THR L CB  1 
ATOM   7731  O OG1 . THR C 3 75  ? 84.408  119.738 142.185 1.00 220.51 ? 75  THR L OG1 1 
ATOM   7732  C CG2 . THR C 3 75  ? 86.107  118.461 141.121 1.00 109.35 ? 75  THR L CG2 1 
ATOM   7733  N N   . ASP C 3 76  ? 85.038  120.038 145.506 1.00 138.28 ? 76  ASP L N   1 
ATOM   7734  C CA  . ASP C 3 76  ? 84.722  121.026 146.523 1.00 210.75 ? 76  ASP L CA  1 
ATOM   7735  C C   . ASP C 3 76  ? 85.473  120.641 147.789 1.00 164.42 ? 76  ASP L C   1 
ATOM   7736  O O   . ASP C 3 76  ? 85.160  119.632 148.412 1.00 143.79 ? 76  ASP L O   1 
ATOM   7737  C CB  . ASP C 3 76  ? 83.215  121.121 146.799 1.00 331.28 ? 76  ASP L CB  1 
ATOM   7738  C CG  . ASP C 3 76  ? 82.351  121.485 145.600 1.00 371.57 ? 76  ASP L CG  1 
ATOM   7739  O OD1 . ASP C 3 76  ? 82.782  122.343 144.801 1.00 255.21 ? 76  ASP L OD1 1 
ATOM   7740  O OD2 . ASP C 3 76  ? 81.240  120.908 145.482 1.00 439.54 ? 76  ASP L OD2 1 
ATOM   7741  N N   . PHE C 3 77  ? 86.456  121.462 148.162 1.00 133.52 ? 77  PHE L N   1 
ATOM   7742  C CA  . PHE C 3 77  ? 87.278  121.207 149.336 1.00 112.72 ? 77  PHE L CA  1 
ATOM   7743  C C   . PHE C 3 77  ? 87.240  122.421 150.241 1.00 95.14  ? 77  PHE L C   1 
ATOM   7744  O O   . PHE C 3 77  ? 87.204  123.554 149.758 1.00 148.03 ? 77  PHE L O   1 
ATOM   7745  C CB  . PHE C 3 77  ? 88.726  120.919 148.936 1.00 139.74 ? 77  PHE L CB  1 
ATOM   7746  C CG  . PHE C 3 77  ? 88.903  119.640 148.161 1.00 126.38 ? 77  PHE L CG  1 
ATOM   7747  C CD1 . PHE C 3 77  ? 88.917  118.447 148.819 1.00 109.92 ? 77  PHE L CD1 1 
ATOM   7748  C CD2 . PHE C 3 77  ? 89.063  119.622 146.787 1.00 106.46 ? 77  PHE L CD2 1 
ATOM   7749  C CE1 . PHE C 3 77  ? 89.063  117.257 148.131 1.00 153.80 ? 77  PHE L CE1 1 
ATOM   7750  C CE2 . PHE C 3 77  ? 89.202  118.430 146.103 1.00 106.84 ? 77  PHE L CE2 1 
ATOM   7751  C CZ  . PHE C 3 77  ? 89.204  117.242 146.771 1.00 127.04 ? 77  PHE L CZ  1 
ATOM   7752  N N   . THR C 3 78  ? 87.282  122.177 151.558 1.00 116.11 ? 78  THR L N   1 
ATOM   7753  C CA  . THR C 3 78  ? 87.255  123.227 152.580 1.00 115.54 ? 78  THR L CA  1 
ATOM   7754  C C   . THR C 3 78  ? 88.202  122.928 153.733 1.00 127.18 ? 78  THR L C   1 
ATOM   7755  O O   . THR C 3 78  ? 88.185  121.831 154.341 1.00 168.26 ? 78  THR L O   1 
ATOM   7756  C CB  . THR C 3 78  ? 85.879  123.367 153.205 1.00 193.94 ? 78  THR L CB  1 
ATOM   7757  O OG1 . THR C 3 78  ? 85.423  122.068 153.608 1.00 251.56 ? 78  THR L OG1 1 
ATOM   7758  C CG2 . THR C 3 78  ? 84.918  123.997 152.229 1.00 263.01 ? 78  THR L CG2 1 
ATOM   7759  N N   . LEU C 3 79  ? 89.048  123.926 153.993 1.00 95.41  ? 79  LEU L N   1 
ATOM   7760  C CA  . LEU C 3 79  ? 89.801  123.917 155.224 1.00 116.43 ? 79  LEU L CA  1 
ATOM   7761  C C   . LEU C 3 79  ? 88.984  124.777 156.180 1.00 148.70 ? 79  LEU L C   1 
ATOM   7762  O O   . LEU C 3 79  ? 88.578  125.877 155.771 1.00 149.62 ? 79  LEU L O   1 
ATOM   7763  C CB  . LEU C 3 79  ? 91.235  124.433 154.988 1.00 86.27  ? 79  LEU L CB  1 
ATOM   7764  C CG  . LEU C 3 79  ? 91.975  124.828 156.270 1.00 119.02 ? 79  LEU L CG  1 
ATOM   7765  C CD1 . LEU C 3 79  ? 92.332  123.640 157.130 1.00 131.79 ? 79  LEU L CD1 1 
ATOM   7766  C CD2 . LEU C 3 79  ? 93.209  125.598 155.968 1.00 131.85 ? 79  LEU L CD2 1 
ATOM   7767  N N   . THR C 3 80  ? 88.777  124.279 157.419 1.00 156.57 ? 80  THR L N   1 
ATOM   7768  C CA  . THR C 3 80  ? 88.038  125.016 158.436 1.00 166.56 ? 80  THR L CA  1 
ATOM   7769  C C   . THR C 3 80  ? 88.885  125.130 159.693 1.00 142.28 ? 80  THR L C   1 
ATOM   7770  O O   . THR C 3 80  ? 89.631  124.208 160.005 1.00 172.05 ? 80  THR L O   1 
ATOM   7771  C CB  . THR C 3 80  ? 86.688  124.370 158.744 1.00 213.96 ? 80  THR L CB  1 
ATOM   7772  O OG1 . THR C 3 80  ? 86.931  123.100 159.338 1.00 215.60 ? 80  THR L OG1 1 
ATOM   7773  C CG2 . THR C 3 80  ? 85.827  124.223 157.511 1.00 256.29 ? 80  THR L CG2 1 
ATOM   7774  N N   . ILE C 3 81  ? 88.787  126.273 160.384 1.00 126.25 ? 81  ILE L N   1 
ATOM   7775  C CA  . ILE C 3 81  ? 89.486  126.475 161.645 1.00 153.70 ? 81  ILE L CA  1 
ATOM   7776  C C   . ILE C 3 81  ? 88.368  126.625 162.666 1.00 190.55 ? 81  ILE L C   1 
ATOM   7777  O O   . ILE C 3 81  ? 87.565  127.541 162.489 1.00 187.41 ? 81  ILE L O   1 
ATOM   7778  C CB  . ILE C 3 81  ? 90.459  127.683 161.640 1.00 168.86 ? 81  ILE L CB  1 
ATOM   7779  C CG1 . ILE C 3 81  ? 91.289  127.801 160.346 1.00 183.68 ? 81  ILE L CG1 1 
ATOM   7780  C CG2 . ILE C 3 81  ? 91.347  127.631 162.880 1.00 136.17 ? 81  ILE L CG2 1 
ATOM   7781  C CD1 . ILE C 3 81  ? 92.226  129.029 160.252 1.00 170.82 ? 81  ILE L CD1 1 
ATOM   7782  N N   . SER C 3 82  ? 88.330  125.731 163.677 1.00 184.94 ? 82  SER L N   1 
ATOM   7783  C CA  . SER C 3 82  ? 87.216  125.602 164.614 1.00 203.62 ? 82  SER L CA  1 
ATOM   7784  C C   . SER C 3 82  ? 87.033  126.843 165.473 1.00 218.37 ? 82  SER L C   1 
ATOM   7785  O O   . SER C 3 82  ? 85.906  127.198 165.815 1.00 261.74 ? 82  SER L O   1 
ATOM   7786  C CB  . SER C 3 82  ? 87.391  124.412 165.512 1.00 175.15 ? 82  SER L CB  1 
ATOM   7787  O OG  . SER C 3 82  ? 87.292  123.239 164.735 1.00 263.42 ? 82  SER L OG  1 
ATOM   7788  N N   . SER C 3 83  ? 88.158  127.458 165.834 1.00 218.35 ? 83  SER L N   1 
ATOM   7789  C CA  . SER C 3 83  ? 88.172  128.577 166.752 1.00 245.86 ? 83  SER L CA  1 
ATOM   7790  C C   . SER C 3 83  ? 89.487  129.331 166.557 1.00 188.04 ? 83  SER L C   1 
ATOM   7791  O O   . SER C 3 83  ? 90.502  129.049 167.196 1.00 145.21 ? 83  SER L O   1 
ATOM   7792  C CB  . SER C 3 83  ? 87.951  128.126 168.181 1.00 300.90 ? 83  SER L CB  1 
ATOM   7793  O OG  . SER C 3 83  ? 87.788  129.247 169.039 1.00 306.40 ? 83  SER L OG  1 
ATOM   7794  N N   . VAL C 3 84  ? 89.428  130.302 165.641 1.00 145.84 ? 84  VAL L N   1 
ATOM   7795  C CA  . VAL C 3 84  ? 90.541  131.148 165.248 1.00 136.64 ? 84  VAL L CA  1 
ATOM   7796  C C   . VAL C 3 84  ? 91.223  131.774 166.461 1.00 123.63 ? 84  VAL L C   1 
ATOM   7797  O O   . VAL C 3 84  ? 90.559  132.375 167.310 1.00 204.58 ? 84  VAL L O   1 
ATOM   7798  C CB  . VAL C 3 84  ? 90.019  132.235 164.276 1.00 145.30 ? 84  VAL L CB  1 
ATOM   7799  C CG1 . VAL C 3 84  ? 90.871  133.485 164.213 1.00 155.24 ? 84  VAL L CG1 1 
ATOM   7800  C CG2 . VAL C 3 84  ? 89.827  131.662 162.880 1.00 155.01 ? 84  VAL L CG2 1 
ATOM   7801  N N   . GLN C 3 85  ? 92.555  131.674 166.494 1.00 135.54 ? 85  GLN L N   1 
ATOM   7802  C CA  . GLN C 3 85  ? 93.374  132.418 167.434 1.00 157.35 ? 85  GLN L CA  1 
ATOM   7803  C C   . GLN C 3 85  ? 94.068  133.578 166.704 1.00 160.04 ? 85  GLN L C   1 
ATOM   7804  O O   . GLN C 3 85  ? 94.134  133.657 165.484 1.00 130.13 ? 85  GLN L O   1 
ATOM   7805  C CB  . GLN C 3 85  ? 94.324  131.443 168.122 1.00 155.67 ? 85  GLN L CB  1 
ATOM   7806  C CG  . GLN C 3 85  ? 93.575  130.227 168.672 1.00 199.23 ? 85  GLN L CG  1 
ATOM   7807  C CD  . GLN C 3 85  ? 94.303  129.416 169.716 1.00 300.12 ? 85  GLN L CD  1 
ATOM   7808  O OE1 . GLN C 3 85  ? 95.343  129.812 170.245 1.00 306.10 ? 85  GLN L OE1 1 
ATOM   7809  N NE2 . GLN C 3 85  ? 93.741  128.256 170.030 1.00 294.55 ? 85  GLN L NE2 1 
ATOM   7810  N N   . ALA C 3 86  ? 94.587  134.513 167.483 1.00 184.51 ? 86  ALA L N   1 
ATOM   7811  C CA  . ALA C 3 86  ? 95.262  135.671 166.937 1.00 172.18 ? 86  ALA L CA  1 
ATOM   7812  C C   . ALA C 3 86  ? 96.487  135.245 166.141 1.00 181.82 ? 86  ALA L C   1 
ATOM   7813  O O   . ALA C 3 86  ? 96.901  135.994 165.253 1.00 226.04 ? 86  ALA L O   1 
ATOM   7814  C CB  . ALA C 3 86  ? 95.655  136.580 168.082 1.00 253.88 ? 86  ALA L CB  1 
ATOM   7815  N N   . GLU C 3 87  ? 97.067  134.065 166.468 1.00 172.42 ? 87  GLU L N   1 
ATOM   7816  C CA  . GLU C 3 87  ? 98.273  133.582 165.802 1.00 183.01 ? 87  GLU L CA  1 
ATOM   7817  C C   . GLU C 3 87  ? 97.996  133.108 164.376 1.00 128.33 ? 87  GLU L C   1 
ATOM   7818  O O   . GLU C 3 87  ? 98.957  132.833 163.672 1.00 164.09 ? 87  GLU L O   1 
ATOM   7819  C CB  . GLU C 3 87  ? 98.968  132.514 166.661 1.00 236.99 ? 87  GLU L CB  1 
ATOM   7820  C CG  . GLU C 3 87  ? 98.203  131.210 166.829 1.00 298.57 ? 87  GLU L CG  1 
ATOM   7821  C CD  . GLU C 3 87  ? 98.758  130.225 167.848 1.00 382.26 ? 87  GLU L CD  1 
ATOM   7822  O OE1 . GLU C 3 87  ? 99.223  130.675 168.916 1.00 433.55 ? 87  GLU L OE1 1 
ATOM   7823  O OE2 . GLU C 3 87  ? 98.711  129.001 167.575 1.00 412.79 ? 87  GLU L OE2 1 
ATOM   7824  N N   . ASP C 3 88  ? 96.722  133.013 163.955 1.00 133.25 ? 88  ASP L N   1 
ATOM   7825  C CA  . ASP C 3 88  ? 96.336  132.345 162.722 1.00 127.47 ? 88  ASP L CA  1 
ATOM   7826  C C   . ASP C 3 88  ? 96.271  133.273 161.507 1.00 105.85 ? 88  ASP L C   1 
ATOM   7827  O O   . ASP C 3 88  ? 95.982  132.776 160.428 1.00 88.78  ? 88  ASP L O   1 
ATOM   7828  C CB  . ASP C 3 88  ? 95.003  131.613 162.904 1.00 125.67 ? 88  ASP L CB  1 
ATOM   7829  C CG  . ASP C 3 88  ? 95.105  130.398 163.831 1.00 174.81 ? 88  ASP L CG  1 
ATOM   7830  O OD1 . ASP C 3 88  ? 96.184  129.717 163.813 1.00 169.84 ? 88  ASP L OD1 1 
ATOM   7831  O OD2 . ASP C 3 88  ? 94.099  130.102 164.557 1.00 185.52 ? 88  ASP L OD2 1 
ATOM   7832  N N   . LEU C 3 89  ? 96.566  134.574 161.615 1.00 119.48 ? 89  LEU L N   1 
ATOM   7833  C CA  . LEU C 3 89  ? 96.500  135.435 160.436 1.00 142.66 ? 89  LEU L CA  1 
ATOM   7834  C C   . LEU C 3 89  ? 97.689  135.130 159.523 1.00 125.78 ? 89  LEU L C   1 
ATOM   7835  O O   . LEU C 3 89  ? 98.815  135.080 160.023 1.00 110.11 ? 89  LEU L O   1 
ATOM   7836  C CB  . LEU C 3 89  ? 96.430  136.908 160.859 1.00 152.79 ? 89  LEU L CB  1 
ATOM   7837  C CG  . LEU C 3 89  ? 97.720  137.568 161.315 1.00 193.04 ? 89  LEU L CG  1 
ATOM   7838  C CD1 . LEU C 3 89  ? 98.320  138.343 160.158 1.00 226.19 ? 89  LEU L CD1 1 
ATOM   7839  C CD2 . LEU C 3 89  ? 97.503  138.470 162.525 1.00 268.37 ? 89  LEU L CD2 1 
ATOM   7840  N N   . ALA C 3 90  ? 97.391  134.929 158.211 1.00 91.41  ? 90  ALA L N   1 
ATOM   7841  C CA  . ALA C 3 90  ? 98.240  134.221 157.257 1.00 91.30  ? 90  ALA L CA  1 
ATOM   7842  C C   . ALA C 3 90  ? 97.606  134.186 155.887 1.00 101.14 ? 90  ALA L C   1 
ATOM   7843  O O   . ALA C 3 90  ? 96.428  134.540 155.781 1.00 139.94 ? 90  ALA L O   1 
ATOM   7844  C CB  . ALA C 3 90  ? 98.434  132.777 157.647 1.00 93.86  ? 90  ALA L CB  1 
ATOM   7845  N N   . LEU C 3 91  ? 98.370  133.738 154.864 1.00 99.55  ? 91  LEU L N   1 
ATOM   7846  C CA  . LEU C 3 91  ? 97.755  133.296 153.615 1.00 104.55 ? 91  LEU L CA  1 
ATOM   7847  C C   . LEU C 3 91  ? 97.675  131.807 153.720 1.00 95.25  ? 91  LEU L C   1 
ATOM   7848  O O   . LEU C 3 91  ? 98.615  131.217 154.240 1.00 144.86 ? 91  LEU L O   1 
ATOM   7849  C CB  . LEU C 3 91  ? 98.512  133.648 152.336 1.00 92.23  ? 91  LEU L CB  1 
ATOM   7850  C CG  . LEU C 3 91  ? 98.530  135.120 151.991 1.00 184.83 ? 91  LEU L CG  1 
ATOM   7851  C CD1 . LEU C 3 91  ? 99.661  135.809 152.765 1.00 244.10 ? 91  LEU L CD1 1 
ATOM   7852  C CD2 . LEU C 3 91  ? 98.610  135.328 150.484 1.00 249.21 ? 91  LEU L CD2 1 
ATOM   7853  N N   . TYR C 3 92  ? 96.566  131.253 153.206 1.00 99.79  ? 92  TYR L N   1 
ATOM   7854  C CA  . TYR C 3 92  ? 96.368  129.815 153.128 1.00 89.09  ? 92  TYR L CA  1 
ATOM   7855  C C   . TYR C 3 92  ? 96.366  129.430 151.667 1.00 55.01  ? 92  TYR L C   1 
ATOM   7856  O O   . TYR C 3 92  ? 95.561  129.976 150.946 1.00 81.60  ? 92  TYR L O   1 
ATOM   7857  C CB  . TYR C 3 92  ? 95.102  129.394 153.870 1.00 68.03  ? 92  TYR L CB  1 
ATOM   7858  C CG  . TYR C 3 92  ? 95.289  129.547 155.373 1.00 74.85  ? 92  TYR L CG  1 
ATOM   7859  C CD1 . TYR C 3 92  ? 95.132  130.745 155.953 1.00 77.40  ? 92  TYR L CD1 1 
ATOM   7860  C CD2 . TYR C 3 92  ? 95.651  128.515 156.211 1.00 102.97 ? 92  TYR L CD2 1 
ATOM   7861  C CE1 . TYR C 3 92  ? 95.308  130.915 157.310 1.00 93.85  ? 92  TYR L CE1 1 
ATOM   7862  C CE2 . TYR C 3 92  ? 95.832  128.678 157.565 1.00 113.62 ? 92  TYR L CE2 1 
ATOM   7863  C CZ  . TYR C 3 92  ? 95.664  129.893 158.133 1.00 76.59  ? 92  TYR L CZ  1 
ATOM   7864  O OH  . TYR C 3 92  ? 95.809  130.050 159.475 1.00 108.13 ? 92  TYR L OH  1 
ATOM   7865  N N   . TYR C 3 93  ? 97.238  128.498 151.284 1.00 44.96  ? 93  TYR L N   1 
ATOM   7866  C CA  . TYR C 3 93  ? 97.176  127.942 149.964 1.00 66.35  ? 93  TYR L CA  1 
ATOM   7867  C C   . TYR C 3 93  ? 96.663  126.509 149.919 1.00 68.30  ? 93  TYR L C   1 
ATOM   7868  O O   . TYR C 3 93  ? 97.101  125.728 150.700 1.00 47.22  ? 93  TYR L O   1 
ATOM   7869  C CB  . TYR C 3 93  ? 98.590  127.999 149.449 1.00 68.30  ? 93  TYR L CB  1 
ATOM   7870  C CG  . TYR C 3 93  ? 99.242  129.377 149.355 1.00 62.80  ? 93  TYR L CG  1 
ATOM   7871  C CD1 . TYR C 3 93  ? 99.163  130.200 148.301 1.00 86.30  ? 93  TYR L CD1 1 
ATOM   7872  C CD2 . TYR C 3 93  ? 99.979  129.829 150.358 1.00 79.85  ? 93  TYR L CD2 1 
ATOM   7873  C CE1 . TYR C 3 93  ? 99.813  131.417 148.255 1.00 99.45  ? 93  TYR L CE1 1 
ATOM   7874  C CE2 . TYR C 3 93  ? 100.645 131.010 150.358 1.00 87.92  ? 93  TYR L CE2 1 
ATOM   7875  C CZ  . TYR C 3 93  ? 100.561 131.842 149.311 1.00 96.52  ? 93  TYR L CZ  1 
ATOM   7876  O OH  . TYR C 3 93  ? 101.288 132.983 149.532 1.00 157.65 ? 93  TYR L OH  1 
ATOM   7877  N N   . CYS C 3 94  ? 95.740  126.179 148.994 1.00 80.66  ? 94  CYS L N   1 
ATOM   7878  C CA  . CYS C 3 94  ? 95.436  124.797 148.682 1.00 62.77  ? 94  CYS L CA  1 
ATOM   7879  C C   . CYS C 3 94  ? 96.397  124.362 147.578 1.00 61.12  ? 94  CYS L C   1 
ATOM   7880  O O   . CYS C 3 94  ? 96.795  125.189 146.796 1.00 66.95  ? 94  CYS L O   1 
ATOM   7881  C CB  . CYS C 3 94  ? 93.982  124.634 148.290 1.00 85.62  ? 94  CYS L CB  1 
ATOM   7882  S SG  . CYS C 3 94  ? 93.439  125.232 146.650 1.00 138.83 ? 94  CYS L SG  1 
ATOM   7883  N N   . GLN C 3 95  ? 96.760  123.078 147.527 1.00 58.46  ? 95  GLN L N   1 
ATOM   7884  C CA  . GLN C 3 95  ? 97.584  122.450 146.501 1.00 52.87  ? 95  GLN L CA  1 
ATOM   7885  C C   . GLN C 3 95  ? 97.022  121.092 146.161 1.00 54.95  ? 95  GLN L C   1 
ATOM   7886  O O   . GLN C 3 95  ? 96.694  120.356 147.103 1.00 75.79  ? 95  GLN L O   1 
ATOM   7887  C CB  . GLN C 3 95  ? 98.963  122.146 147.074 1.00 70.87  ? 95  GLN L CB  1 
ATOM   7888  C CG  . GLN C 3 95  ? 100.002 121.706 146.054 1.00 79.26  ? 95  GLN L CG  1 
ATOM   7889  C CD  . GLN C 3 95  ? 100.990 120.729 146.614 1.00 72.57  ? 95  GLN L CD  1 
ATOM   7890  O OE1 . GLN C 3 95  ? 101.667 120.933 147.603 1.00 68.43  ? 95  GLN L OE1 1 
ATOM   7891  N NE2 . GLN C 3 95  ? 101.096 119.593 146.003 1.00 113.71 ? 95  GLN L NE2 1 
ATOM   7892  N N   . GLN C 3 96  ? 96.925  120.769 144.863 1.00 58.13  ? 96  GLN L N   1 
ATOM   7893  C CA  . GLN C 3 96  ? 96.651  119.392 144.481 1.00 80.96  ? 96  GLN L CA  1 
ATOM   7894  C C   . GLN C 3 96  ? 97.938  118.575 144.617 1.00 62.10  ? 96  GLN L C   1 
ATOM   7895  O O   . GLN C 3 96  ? 98.990  119.096 144.295 1.00 108.71 ? 96  GLN L O   1 
ATOM   7896  C CB  . GLN C 3 96  ? 96.033  119.233 143.072 1.00 63.73  ? 96  GLN L CB  1 
ATOM   7897  C CG  . GLN C 3 96  ? 96.932  118.604 141.978 1.00 41.10  ? 96  GLN L CG  1 
ATOM   7898  C CD  . GLN C 3 96  ? 97.610  119.765 141.432 1.00 81.55  ? 96  GLN L CD  1 
ATOM   7899  O OE1 . GLN C 3 96  ? 97.632  120.809 142.077 1.00 145.73 ? 96  GLN L OE1 1 
ATOM   7900  N NE2 . GLN C 3 96  ? 98.126  119.635 140.239 1.00 127.11 ? 96  GLN L NE2 1 
ATOM   7901  N N   . HIS C 3 97  ? 97.858  117.319 145.034 1.00 55.18  ? 97  HIS L N   1 
ATOM   7902  C CA  . HIS C 3 97  ? 98.913  116.411 144.667 1.00 74.49  ? 97  HIS L CA  1 
ATOM   7903  C C   . HIS C 3 97  ? 98.484  115.211 143.847 1.00 64.42  ? 97  HIS L C   1 
ATOM   7904  O O   . HIS C 3 97  ? 99.051  114.128 143.987 1.00 70.98  ? 97  HIS L O   1 
ATOM   7905  C CB  . HIS C 3 97  ? 99.692  116.111 145.915 1.00 81.34  ? 97  HIS L CB  1 
ATOM   7906  C CG  . HIS C 3 97  ? 98.975  115.696 147.048 1.00 68.28  ? 97  HIS L CG  1 
ATOM   7907  N ND1 . HIS C 3 97  ? 98.659  116.583 148.003 1.00 69.92  ? 97  HIS L ND1 1 
ATOM   7908  C CD2 . HIS C 3 97  ? 98.613  114.521 147.413 1.00 87.69  ? 97  HIS L CD2 1 
ATOM   7909  C CE1 . HIS C 3 97  ? 98.089  115.880 148.957 1.00 103.76 ? 97  HIS L CE1 1 
ATOM   7910  N NE2 . HIS C 3 97  ? 98.043  114.629 148.630 1.00 72.98  ? 97  HIS L NE2 1 
ATOM   7911  N N   . TYR C 3 98  ? 97.521  115.442 142.980 1.00 47.36  ? 98  TYR L N   1 
ATOM   7912  C CA  . TYR C 3 98  ? 97.123  114.396 142.096 1.00 63.58  ? 98  TYR L CA  1 
ATOM   7913  C C   . TYR C 3 98  ? 97.999  114.384 140.859 1.00 56.01  ? 98  TYR L C   1 
ATOM   7914  O O   . TYR C 3 98  ? 98.085  113.320 140.248 1.00 56.58  ? 98  TYR L O   1 
ATOM   7915  C CB  . TYR C 3 98  ? 95.611  114.496 141.909 1.00 77.08  ? 98  TYR L CB  1 
ATOM   7916  C CG  . TYR C 3 98  ? 94.975  113.433 141.031 1.00 77.67  ? 98  TYR L CG  1 
ATOM   7917  C CD1 . TYR C 3 98  ? 94.919  113.575 139.648 1.00 95.11  ? 98  TYR L CD1 1 
ATOM   7918  C CD2 . TYR C 3 98  ? 94.456  112.290 141.585 1.00 65.74  ? 98  TYR L CD2 1 
ATOM   7919  C CE1 . TYR C 3 98  ? 94.333  112.610 138.847 1.00 125.21 ? 98  TYR L CE1 1 
ATOM   7920  C CE2 . TYR C 3 98  ? 93.889  111.307 140.801 1.00 121.14 ? 98  TYR L CE2 1 
ATOM   7921  C CZ  . TYR C 3 98  ? 93.812  111.460 139.427 1.00 171.69 ? 98  TYR L CZ  1 
ATOM   7922  O OH  . TYR C 3 98  ? 93.227  110.448 138.708 1.00 234.37 ? 98  TYR L OH  1 
ATOM   7923  N N   . THR C 3 99  ? 98.622  115.485 140.497 1.00 59.43  ? 99  THR L N   1 
ATOM   7924  C CA  . THR C 3 99  ? 99.693  115.293 139.544 1.00 85.36  ? 99  THR L CA  1 
ATOM   7925  C C   . THR C 3 99  ? 100.974 116.009 139.929 1.00 71.59  ? 99  THR L C   1 
ATOM   7926  O O   . THR C 3 99  ? 100.994 116.990 140.663 1.00 71.21  ? 99  THR L O   1 
ATOM   7927  C CB  . THR C 3 99  ? 99.350  115.759 138.125 1.00 117.61 ? 99  THR L CB  1 
ATOM   7928  O OG1 . THR C 3 99  ? 99.185  117.170 138.189 1.00 161.63 ? 99  THR L OG1 1 
ATOM   7929  C CG2 . THR C 3 99  ? 98.142  115.065 137.538 1.00 133.17 ? 99  THR L CG2 1 
ATOM   7930  N N   . ILE C 3 100 ? 102.058 115.477 139.379 1.00 57.50  ? 100 ILE L N   1 
ATOM   7931  C CA  . ILE C 3 100 ? 103.306 116.198 139.409 1.00 65.42  ? 100 ILE L CA  1 
ATOM   7932  C C   . ILE C 3 100 ? 103.502 116.613 137.975 1.00 51.80  ? 100 ILE L C   1 
ATOM   7933  O O   . ILE C 3 100 ? 103.395 115.745 137.147 1.00 39.44  ? 100 ILE L O   1 
ATOM   7934  C CB  . ILE C 3 100 ? 104.526 115.487 140.048 1.00 63.83  ? 100 ILE L CB  1 
ATOM   7935  C CG1 . ILE C 3 100 ? 105.731 115.491 139.148 1.00 64.83  ? 100 ILE L CG1 1 
ATOM   7936  C CG2 . ILE C 3 100 ? 104.320 114.067 140.527 1.00 57.89  ? 100 ILE L CG2 1 
ATOM   7937  C CD1 . ILE C 3 100 ? 106.886 115.089 139.999 1.00 107.88 ? 100 ILE L CD1 1 
ATOM   7938  N N   . PRO C 3 101 ? 103.781 117.926 137.699 1.00 74.79  ? 101 PRO L N   1 
ATOM   7939  C CA  . PRO C 3 101 ? 103.967 119.006 138.689 1.00 72.06  ? 101 PRO L CA  1 
ATOM   7940  C C   . PRO C 3 101 ? 102.718 119.400 139.464 1.00 65.72  ? 101 PRO L C   1 
ATOM   7941  O O   . PRO C 3 101 ? 101.641 119.432 138.869 1.00 62.23  ? 101 PRO L O   1 
ATOM   7942  C CB  . PRO C 3 101 ? 104.035 120.255 137.837 1.00 67.03  ? 101 PRO L CB  1 
ATOM   7943  C CG  . PRO C 3 101 ? 103.234 119.876 136.606 1.00 82.59  ? 101 PRO L CG  1 
ATOM   7944  C CD  . PRO C 3 101 ? 103.891 118.516 136.369 1.00 85.94  ? 101 PRO L CD  1 
ATOM   7945  N N   . PRO C 3 102 ? 102.805 119.671 140.763 1.00 46.57  ? 102 PRO L N   1 
ATOM   7946  C CA  . PRO C 3 102 ? 101.652 120.163 141.465 1.00 53.33  ? 102 PRO L CA  1 
ATOM   7947  C C   . PRO C 3 102 ? 101.341 121.588 141.049 1.00 78.12  ? 102 PRO L C   1 
ATOM   7948  O O   . PRO C 3 102 ? 102.161 122.278 140.433 1.00 108.99 ? 102 PRO L O   1 
ATOM   7949  C CB  . PRO C 3 102 ? 102.099 120.248 142.946 1.00 51.76  ? 102 PRO L CB  1 
ATOM   7950  C CG  . PRO C 3 102 ? 103.572 120.305 142.905 1.00 51.27  ? 102 PRO L CG  1 
ATOM   7951  C CD  . PRO C 3 102 ? 103.974 119.552 141.620 1.00 44.59  ? 102 PRO L CD  1 
ATOM   7952  N N   . THR C 3 103 ? 100.169 122.054 141.483 1.00 73.80  ? 103 THR L N   1 
ATOM   7953  C CA  . THR C 3 103 ? 99.761  123.427 141.276 1.00 95.71  ? 103 THR L CA  1 
ATOM   7954  C C   . THR C 3 103 ? 99.027  123.924 142.513 1.00 75.46  ? 103 THR L C   1 
ATOM   7955  O O   . THR C 3 103 ? 98.434  123.160 143.247 1.00 61.77  ? 103 THR L O   1 
ATOM   7956  C CB  . THR C 3 103 ? 98.877  123.530 140.017 1.00 109.17 ? 103 THR L CB  1 
ATOM   7957  O OG1 . THR C 3 103 ? 97.943  122.493 139.968 1.00 59.74  ? 103 THR L OG1 1 
ATOM   7958  C CG2 . THR C 3 103 ? 99.541  123.256 138.696 1.00 168.29 ? 103 THR L CG2 1 
ATOM   7959  N N   . PHE C 3 104 ? 99.025  125.226 142.717 1.00 72.97  ? 104 PHE L N   1 
ATOM   7960  C CA  . PHE C 3 104 ? 98.408  125.744 143.907 1.00 76.04  ? 104 PHE L CA  1 
ATOM   7961  C C   . PHE C 3 104 ? 97.313  126.778 143.635 1.00 91.11  ? 104 PHE L C   1 
ATOM   7962  O O   . PHE C 3 104 ? 97.270  127.421 142.591 1.00 107.77 ? 104 PHE L O   1 
ATOM   7963  C CB  . PHE C 3 104 ? 99.544  126.417 144.649 1.00 86.19  ? 104 PHE L CB  1 
ATOM   7964  C CG  . PHE C 3 104 ? 100.716 125.609 145.117 1.00 90.61  ? 104 PHE L CG  1 
ATOM   7965  C CD1 . PHE C 3 104 ? 101.681 125.170 144.225 1.00 97.74  ? 104 PHE L CD1 1 
ATOM   7966  C CD2 . PHE C 3 104 ? 100.875 125.337 146.476 1.00 70.92  ? 104 PHE L CD2 1 
ATOM   7967  C CE1 . PHE C 3 104 ? 102.764 124.447 144.694 1.00 75.90  ? 104 PHE L CE1 1 
ATOM   7968  C CE2 . PHE C 3 104 ? 101.974 124.632 146.924 1.00 56.28  ? 104 PHE L CE2 1 
ATOM   7969  C CZ  . PHE C 3 104 ? 102.909 124.206 146.016 1.00 54.33  ? 104 PHE L CZ  1 
ATOM   7970  N N   . GLY C 3 105 ? 96.457  126.984 144.642 1.00 105.11 ? 105 GLY L N   1 
ATOM   7971  C CA  . GLY C 3 105 ? 95.594  128.156 144.738 1.00 141.37 ? 105 GLY L CA  1 
ATOM   7972  C C   . GLY C 3 105 ? 96.313  129.497 144.859 1.00 87.42  ? 105 GLY L C   1 
ATOM   7973  O O   . GLY C 3 105 ? 97.418  129.553 145.280 1.00 97.30  ? 105 GLY L O   1 
ATOM   7974  N N   . GLY C 3 106 ? 95.659  130.576 144.463 1.00 114.28 ? 106 GLY L N   1 
ATOM   7975  C CA  . GLY C 3 106 ? 96.172  131.908 144.671 1.00 154.27 ? 106 GLY L CA  1 
ATOM   7976  C C   . GLY C 3 106 ? 96.032  132.365 146.122 1.00 149.61 ? 106 GLY L C   1 
ATOM   7977  O O   . GLY C 3 106 ? 96.559  133.442 146.442 1.00 164.28 ? 106 GLY L O   1 
ATOM   7978  N N   . GLY C 3 107 ? 95.336  131.579 146.972 1.00 89.04  ? 107 GLY L N   1 
ATOM   7979  C CA  . GLY C 3 107 ? 95.478  131.763 148.410 1.00 123.90 ? 107 GLY L CA  1 
ATOM   7980  C C   . GLY C 3 107 ? 94.481  132.763 149.039 1.00 119.18 ? 107 GLY L C   1 
ATOM   7981  O O   . GLY C 3 107 ? 94.207  133.814 148.481 1.00 153.21 ? 107 GLY L O   1 
ATOM   7982  N N   . THR C 3 108 ? 93.974  132.427 150.229 1.00 117.44 ? 108 THR L N   1 
ATOM   7983  C CA  . THR C 3 108 ? 93.031  133.209 151.008 1.00 95.58  ? 108 THR L CA  1 
ATOM   7984  C C   . THR C 3 108 ? 93.770  133.920 152.140 1.00 110.06 ? 108 THR L C   1 
ATOM   7985  O O   . THR C 3 108 ? 94.403  133.257 152.961 1.00 152.42 ? 108 THR L O   1 
ATOM   7986  C CB  . THR C 3 108 ? 91.998  132.291 151.661 1.00 133.75 ? 108 THR L CB  1 
ATOM   7987  O OG1 . THR C 3 108 ? 91.191  131.688 150.640 1.00 139.37 ? 108 THR L OG1 1 
ATOM   7988  C CG2 . THR C 3 108 ? 91.118  133.007 152.668 1.00 183.33 ? 108 THR L CG2 1 
ATOM   7989  N N   . LYS C 3 109 ? 93.722  135.246 152.191 1.00 108.01 ? 109 LYS L N   1 
ATOM   7990  C CA  . LYS C 3 109 ? 94.329  136.017 153.279 1.00 98.55  ? 109 LYS L CA  1 
ATOM   7991  C C   . LYS C 3 109 ? 93.328  136.097 154.435 1.00 86.02  ? 109 LYS L C   1 
ATOM   7992  O O   . LYS C 3 109 ? 92.288  136.763 154.364 1.00 122.22 ? 109 LYS L O   1 
ATOM   7993  C CB  . LYS C 3 109 ? 94.771  137.372 152.713 1.00 147.54 ? 109 LYS L CB  1 
ATOM   7994  C CG  . LYS C 3 109 ? 95.239  138.430 153.711 1.00 155.95 ? 109 LYS L CG  1 
ATOM   7995  C CD  . LYS C 3 109 ? 96.617  138.139 154.186 1.00 210.79 ? 109 LYS L CD  1 
ATOM   7996  C CE  . LYS C 3 109 ? 97.189  139.227 155.068 1.00 305.96 ? 109 LYS L CE  1 
ATOM   7997  N NZ  . LYS C 3 109 ? 98.330  138.721 155.872 1.00 362.62 ? 109 LYS L NZ  1 
ATOM   7998  N N   . LEU C 3 110 ? 93.610  135.387 155.516 1.00 97.37  ? 110 LEU L N   1 
ATOM   7999  C CA  . LEU C 3 110 ? 92.791  135.485 156.721 1.00 104.91 ? 110 LEU L CA  1 
ATOM   8000  C C   . LEU C 3 110 ? 93.292  136.701 157.474 1.00 106.66 ? 110 LEU L C   1 
ATOM   8001  O O   . LEU C 3 110 ? 94.485  136.918 157.546 1.00 111.95 ? 110 LEU L O   1 
ATOM   8002  C CB  . LEU C 3 110 ? 92.908  134.211 157.546 1.00 107.30 ? 110 LEU L CB  1 
ATOM   8003  C CG  . LEU C 3 110 ? 92.479  134.243 159.000 1.00 103.78 ? 110 LEU L CG  1 
ATOM   8004  C CD1 . LEU C 3 110 ? 91.009  134.515 159.047 1.00 138.63 ? 110 LEU L CD1 1 
ATOM   8005  C CD2 . LEU C 3 110 ? 92.793  132.897 159.702 1.00 106.81 ? 110 LEU L CD2 1 
ATOM   8006  N N   . GLU C 3 111 ? 92.351  137.510 157.958 1.00 129.60 ? 111 GLU L N   1 
ATOM   8007  C CA  . GLU C 3 111 ? 92.598  138.705 158.744 1.00 161.34 ? 111 GLU L CA  1 
ATOM   8008  C C   . GLU C 3 111 ? 91.803  138.590 160.037 1.00 124.14 ? 111 GLU L C   1 
ATOM   8009  O O   . GLU C 3 111 ? 90.776  137.924 160.078 1.00 162.24 ? 111 GLU L O   1 
ATOM   8010  C CB  . GLU C 3 111 ? 92.155  139.958 157.964 1.00 191.27 ? 111 GLU L CB  1 
ATOM   8011  C CG  . GLU C 3 111 ? 92.805  140.113 156.587 1.00 244.92 ? 111 GLU L CG  1 
ATOM   8012  C CD  . GLU C 3 111 ? 92.128  141.118 155.670 1.00 293.00 ? 111 GLU L CD  1 
ATOM   8013  O OE1 . GLU C 3 111 ? 91.660  142.164 156.174 1.00 305.66 ? 111 GLU L OE1 1 
ATOM   8014  O OE2 . GLU C 3 111 ? 92.086  140.848 154.445 1.00 365.05 ? 111 GLU L OE2 1 
ATOM   8015  N N   . ILE C 3 112 ? 92.245  139.291 161.075 1.00 144.03 ? 112 ILE L N   1 
ATOM   8016  C CA  . ILE C 3 112 ? 91.539  139.283 162.342 1.00 138.35 ? 112 ILE L CA  1 
ATOM   8017  C C   . ILE C 3 112 ? 90.769  140.593 162.517 1.00 190.05 ? 112 ILE L C   1 
ATOM   8018  O O   . ILE C 3 112 ? 91.250  141.673 162.146 1.00 205.62 ? 112 ILE L O   1 
ATOM   8019  C CB  . ILE C 3 112 ? 92.538  139.035 163.482 1.00 153.43 ? 112 ILE L CB  1 
ATOM   8020  C CG1 . ILE C 3 112 ? 93.320  137.733 163.294 1.00 165.20 ? 112 ILE L CG1 1 
ATOM   8021  C CG2 . ILE C 3 112 ? 91.862  139.079 164.839 1.00 173.38 ? 112 ILE L CG2 1 
ATOM   8022  C CD1 . ILE C 3 112 ? 92.497  136.518 163.279 1.00 165.09 ? 112 ILE L CD1 1 
ATOM   8023  N N   . LYS C 3 113 ? 89.563  140.461 163.101 1.00 205.63 ? 113 LYS L N   1 
ATOM   8024  C CA  . LYS C 3 113 ? 88.763  141.582 163.571 1.00 208.49 ? 113 LYS L CA  1 
ATOM   8025  C C   . LYS C 3 113 ? 88.881  141.701 165.088 1.00 186.50 ? 113 LYS L C   1 
ATOM   8026  O O   . LYS C 3 113 ? 88.746  140.694 165.795 1.00 186.73 ? 113 LYS L O   1 
ATOM   8027  C CB  . LYS C 3 113 ? 87.307  141.406 163.139 1.00 212.80 ? 113 LYS L CB  1 
ATOM   8028  C CG  . LYS C 3 113 ? 87.001  141.909 161.737 1.00 235.87 ? 113 LYS L CG  1 
ATOM   8029  C CD  . LYS C 3 113 ? 85.711  141.379 161.144 1.00 260.52 ? 113 LYS L CD  1 
ATOM   8030  C CE  . LYS C 3 113 ? 84.450  141.888 161.808 1.00 281.82 ? 113 LYS L CE  1 
ATOM   8031  N NZ  . LYS C 3 113 ? 83.292  141.017 161.489 1.00 282.62 ? 113 LYS L NZ  1 
ATOM   8032  N N   . ARG C 3 114 ? 89.121  142.937 165.556 1.00 166.06 ? 114 ARG L N   1 
ATOM   8033  C CA  . ARG C 3 114 ? 89.192  143.247 166.973 1.00 229.52 ? 114 ARG L CA  1 
ATOM   8034  C C   . ARG C 3 114 ? 88.462  144.557 167.271 1.00 247.39 ? 114 ARG L C   1 
ATOM   8035  O O   . ARG C 3 114 ? 88.040  145.266 166.366 1.00 223.53 ? 114 ARG L O   1 
ATOM   8036  C CB  . ARG C 3 114 ? 90.657  143.313 167.411 1.00 220.57 ? 114 ARG L CB  1 
ATOM   8037  C CG  . ARG C 3 114 ? 91.494  144.340 166.661 1.00 200.35 ? 114 ARG L CG  1 
ATOM   8038  C CD  . ARG C 3 114 ? 92.769  144.670 167.423 1.00 196.03 ? 114 ARG L CD  1 
ATOM   8039  N NE  . ARG C 3 114 ? 92.505  145.520 168.576 1.00 215.72 ? 114 ARG L NE  1 
ATOM   8040  C CZ  . ARG C 3 114 ? 93.162  145.521 169.738 1.00 268.14 ? 114 ARG L CZ  1 
ATOM   8041  N NH1 . ARG C 3 114 ? 92.813  146.387 170.680 1.00 331.01 ? 114 ARG L NH1 1 
ATOM   8042  N NH2 . ARG C 3 114 ? 94.165  144.683 169.958 1.00 271.26 ? 114 ARG L NH2 1 
ATOM   8043  N N   . ALA C 3 115 ? 88.326  144.855 168.569 1.00 294.07 ? 115 ALA L N   1 
ATOM   8044  C CA  . ALA C 3 115 ? 87.851  146.149 169.031 1.00 309.84 ? 115 ALA L CA  1 
ATOM   8045  C C   . ALA C 3 115 ? 88.791  147.248 168.535 1.00 246.94 ? 115 ALA L C   1 
ATOM   8046  O O   . ALA C 3 115 ? 90.001  147.158 168.717 1.00 271.18 ? 115 ALA L O   1 
ATOM   8047  C CB  . ALA C 3 115 ? 87.752  146.159 170.538 1.00 368.34 ? 115 ALA L CB  1 
ATOM   8048  N N   . ASP C 3 116 ? 88.219  148.288 167.918 1.00 206.08 ? 116 ASP L N   1 
ATOM   8049  C CA  . ASP C 3 116 ? 88.971  149.388 167.330 1.00 221.68 ? 116 ASP L CA  1 
ATOM   8050  C C   . ASP C 3 116 ? 89.805  150.097 168.406 1.00 243.30 ? 116 ASP L C   1 
ATOM   8051  O O   . ASP C 3 116 ? 89.404  150.152 169.573 1.00 289.86 ? 116 ASP L O   1 
ATOM   8052  C CB  . ASP C 3 116 ? 88.033  150.391 166.637 1.00 260.51 ? 116 ASP L CB  1 
ATOM   8053  C CG  . ASP C 3 116 ? 87.071  149.847 165.586 1.00 275.18 ? 116 ASP L CG  1 
ATOM   8054  O OD1 . ASP C 3 116 ? 86.919  148.602 165.477 1.00 301.57 ? 116 ASP L OD1 1 
ATOM   8055  O OD2 . ASP C 3 116 ? 86.470  150.681 164.877 1.00 263.39 ? 116 ASP L OD2 1 
ATOM   8056  N N   . ALA C 3 117 ? 90.968  150.641 168.007 1.00 217.70 ? 117 ALA L N   1 
ATOM   8057  C CA  . ALA C 3 117 ? 91.872  151.338 168.917 1.00 255.25 ? 117 ALA L CA  1 
ATOM   8058  C C   . ALA C 3 117 ? 92.641  152.441 168.181 1.00 245.48 ? 117 ALA L C   1 
ATOM   8059  O O   . ALA C 3 117 ? 93.061  152.252 167.041 1.00 210.28 ? 117 ALA L O   1 
ATOM   8060  C CB  . ALA C 3 117 ? 92.804  150.343 169.581 1.00 247.37 ? 117 ALA L CB  1 
ATOM   8061  N N   . ALA C 3 118 ? 92.826  153.589 168.851 1.00 243.77 ? 118 ALA L N   1 
ATOM   8062  C CA  . ALA C 3 118 ? 93.463  154.754 168.256 1.00 222.66 ? 118 ALA L CA  1 
ATOM   8063  C C   . ALA C 3 118 ? 94.980  154.586 168.289 1.00 218.58 ? 118 ALA L C   1 
ATOM   8064  O O   . ALA C 3 118 ? 95.502  153.975 169.232 1.00 181.03 ? 118 ALA L O   1 
ATOM   8065  C CB  . ALA C 3 118 ? 93.062  156.007 168.999 1.00 283.29 ? 118 ALA L CB  1 
ATOM   8066  N N   . PRO C 3 119 ? 95.724  155.130 167.285 1.00 218.39 ? 119 PRO L N   1 
ATOM   8067  C CA  . PRO C 3 119 ? 97.182  154.976 167.222 1.00 201.41 ? 119 PRO L CA  1 
ATOM   8068  C C   . PRO C 3 119 ? 97.901  155.753 168.327 1.00 191.45 ? 119 PRO L C   1 
ATOM   8069  O O   . PRO C 3 119 ? 97.559  156.892 168.617 1.00 256.59 ? 119 PRO L O   1 
ATOM   8070  C CB  . PRO C 3 119 ? 97.549  155.547 165.842 1.00 204.05 ? 119 PRO L CB  1 
ATOM   8071  C CG  . PRO C 3 119 ? 96.456  156.545 165.554 1.00 229.96 ? 119 PRO L CG  1 
ATOM   8072  C CD  . PRO C 3 119 ? 95.208  155.939 166.164 1.00 215.64 ? 119 PRO L CD  1 
ATOM   8073  N N   . THR C 3 120 ? 98.898  155.122 168.946 1.00 206.49 ? 120 THR L N   1 
ATOM   8074  C CA  . THR C 3 120 ? 99.974  155.845 169.601 1.00 202.33 ? 120 THR L CA  1 
ATOM   8075  C C   . THR C 3 120 ? 100.780 156.560 168.515 1.00 210.74 ? 120 THR L C   1 
ATOM   8076  O O   . THR C 3 120 ? 101.311 155.910 167.616 1.00 264.66 ? 120 THR L O   1 
ATOM   8077  C CB  . THR C 3 120 ? 100.858 154.881 170.405 1.00 280.05 ? 120 THR L CB  1 
ATOM   8078  O OG1 . THR C 3 120 ? 100.047 154.179 171.354 1.00 240.26 ? 120 THR L OG1 1 
ATOM   8079  C CG2 . THR C 3 120 ? 102.009 155.578 171.101 1.00 314.80 ? 120 THR L CG2 1 
ATOM   8080  N N   . VAL C 3 121 ? 100.875 157.891 168.579 1.00 217.48 ? 121 VAL L N   1 
ATOM   8081  C CA  . VAL C 3 121 ? 101.561 158.664 167.547 1.00 205.48 ? 121 VAL L CA  1 
ATOM   8082  C C   . VAL C 3 121 ? 102.835 159.247 168.154 1.00 208.51 ? 121 VAL L C   1 
ATOM   8083  O O   . VAL C 3 121 ? 102.796 159.804 169.253 1.00 270.24 ? 121 VAL L O   1 
ATOM   8084  C CB  . VAL C 3 121 ? 100.656 159.761 166.946 1.00 214.56 ? 121 VAL L CB  1 
ATOM   8085  C CG1 . VAL C 3 121 ? 101.425 160.613 165.946 1.00 174.17 ? 121 VAL L CG1 1 
ATOM   8086  C CG2 . VAL C 3 121 ? 99.376  159.191 166.319 1.00 211.07 ? 121 VAL L CG2 1 
ATOM   8087  N N   . SER C 3 122 ? 103.952 159.106 167.417 1.00 194.11 ? 122 SER L N   1 
ATOM   8088  C CA  . SER C 3 122 ? 105.261 159.618 167.798 1.00 238.77 ? 122 SER L CA  1 
ATOM   8089  C C   . SER C 3 122 ? 105.966 160.210 166.579 1.00 233.68 ? 122 SER L C   1 
ATOM   8090  O O   . SER C 3 122 ? 105.830 159.684 165.481 1.00 213.41 ? 122 SER L O   1 
ATOM   8091  C CB  . SER C 3 122 ? 106.097 158.535 168.425 1.00 261.26 ? 122 SER L CB  1 
ATOM   8092  O OG  . SER C 3 122 ? 105.457 158.005 169.580 1.00 277.45 ? 122 SER L OG  1 
ATOM   8093  N N   . ILE C 3 123 ? 106.720 161.300 166.786 1.00 260.19 ? 123 ILE L N   1 
ATOM   8094  C CA  . ILE C 3 123 ? 107.449 161.962 165.713 1.00 245.03 ? 123 ILE L CA  1 
ATOM   8095  C C   . ILE C 3 123 ? 108.903 162.155 166.143 1.00 239.02 ? 123 ILE L C   1 
ATOM   8096  O O   . ILE C 3 123 ? 109.182 162.499 167.293 1.00 194.29 ? 123 ILE L O   1 
ATOM   8097  C CB  . ILE C 3 123 ? 106.789 163.288 165.278 1.00 240.83 ? 123 ILE L CB  1 
ATOM   8098  C CG1 . ILE C 3 123 ? 107.530 163.891 164.080 1.00 199.80 ? 123 ILE L CG1 1 
ATOM   8099  C CG2 . ILE C 3 123 ? 106.667 164.293 166.425 1.00 285.62 ? 123 ILE L CG2 1 
ATOM   8100  C CD1 . ILE C 3 123 ? 106.741 164.938 163.340 1.00 248.88 ? 123 ILE L CD1 1 
ATOM   8101  N N   . PHE C 3 124 ? 109.808 161.933 165.177 1.00 251.91 ? 124 PHE L N   1 
ATOM   8102  C CA  . PHE C 3 124 ? 111.241 161.895 165.402 1.00 261.13 ? 124 PHE L CA  1 
ATOM   8103  C C   . PHE C 3 124 ? 111.905 162.967 164.541 1.00 254.82 ? 124 PHE L C   1 
ATOM   8104  O O   . PHE C 3 124 ? 111.869 162.876 163.314 1.00 167.50 ? 124 PHE L O   1 
ATOM   8105  C CB  . PHE C 3 124 ? 111.779 160.503 165.082 1.00 256.88 ? 124 PHE L CB  1 
ATOM   8106  C CG  . PHE C 3 124 ? 111.137 159.408 165.896 1.00 234.30 ? 124 PHE L CG  1 
ATOM   8107  C CD1 . PHE C 3 124 ? 109.923 158.851 165.518 1.00 233.21 ? 124 PHE L CD1 1 
ATOM   8108  C CD2 . PHE C 3 124 ? 111.746 158.936 167.049 1.00 222.42 ? 124 PHE L CD2 1 
ATOM   8109  C CE1 . PHE C 3 124 ? 109.336 157.850 166.277 1.00 273.61 ? 124 PHE L CE1 1 
ATOM   8110  C CE2 . PHE C 3 124 ? 111.166 157.927 167.807 1.00 184.10 ? 124 PHE L CE2 1 
ATOM   8111  C CZ  . PHE C 3 124 ? 109.959 157.395 167.425 1.00 245.53 ? 124 PHE L CZ  1 
ATOM   8112  N N   . PRO C 3 125 ? 112.529 164.013 165.141 1.00 280.34 ? 125 PRO L N   1 
ATOM   8113  C CA  . PRO C 3 125 ? 113.351 164.954 164.378 1.00 244.32 ? 125 PRO L CA  1 
ATOM   8114  C C   . PRO C 3 125 ? 114.487 164.247 163.633 1.00 225.74 ? 125 PRO L C   1 
ATOM   8115  O O   . PRO C 3 125 ? 115.002 163.247 164.142 1.00 216.72 ? 125 PRO L O   1 
ATOM   8116  C CB  . PRO C 3 125 ? 113.931 165.900 165.448 1.00 269.65 ? 125 PRO L CB  1 
ATOM   8117  C CG  . PRO C 3 125 ? 112.983 165.782 166.629 1.00 293.31 ? 125 PRO L CG  1 
ATOM   8118  C CD  . PRO C 3 125 ? 112.471 164.357 166.575 1.00 310.12 ? 125 PRO L CD  1 
ATOM   8119  N N   . PRO C 3 126 ? 114.919 164.737 162.436 1.00 256.45 ? 126 PRO L N   1 
ATOM   8120  C CA  . PRO C 3 126 ? 116.054 164.167 161.694 1.00 245.90 ? 126 PRO L CA  1 
ATOM   8121  C C   . PRO C 3 126 ? 117.312 163.850 162.510 1.00 265.13 ? 126 PRO L C   1 
ATOM   8122  O O   . PRO C 3 126 ? 117.681 164.604 163.417 1.00 335.62 ? 126 PRO L O   1 
ATOM   8123  C CB  . PRO C 3 126 ? 116.390 165.270 160.674 1.00 242.41 ? 126 PRO L CB  1 
ATOM   8124  C CG  . PRO C 3 126 ? 115.053 165.918 160.392 1.00 243.37 ? 126 PRO L CG  1 
ATOM   8125  C CD  . PRO C 3 126 ? 114.325 165.882 161.721 1.00 278.40 ? 126 PRO L CD  1 
ATOM   8126  N N   . SER C 3 127 ? 117.957 162.727 162.160 1.00 272.40 ? 127 SER L N   1 
ATOM   8127  C CA  . SER C 3 127 ? 119.157 162.234 162.827 1.00 317.17 ? 127 SER L CA  1 
ATOM   8128  C C   . SER C 3 127 ? 120.308 163.220 162.613 1.00 396.12 ? 127 SER L C   1 
ATOM   8129  O O   . SER C 3 127 ? 120.542 163.618 161.478 1.00 434.05 ? 127 SER L O   1 
ATOM   8130  C CB  . SER C 3 127 ? 119.542 160.845 162.321 1.00 266.24 ? 127 SER L CB  1 
ATOM   8131  O OG  . SER C 3 127 ? 118.417 160.063 161.937 1.00 239.47 ? 127 SER L OG  1 
ATOM   8132  N N   . SER C 3 128 ? 121.036 163.608 163.675 1.00 398.45 ? 128 SER L N   1 
ATOM   8133  C CA  . SER C 3 128 ? 122.101 164.604 163.555 1.00 369.07 ? 128 SER L CA  1 
ATOM   8134  C C   . SER C 3 128 ? 123.203 164.162 162.580 1.00 330.80 ? 128 SER L C   1 
ATOM   8135  O O   . SER C 3 128 ? 123.850 165.020 161.977 1.00 262.00 ? 128 SER L O   1 
ATOM   8136  C CB  . SER C 3 128 ? 122.676 164.975 164.909 1.00 368.69 ? 128 SER L CB  1 
ATOM   8137  O OG  . SER C 3 128 ? 123.211 163.845 165.579 1.00 379.95 ? 128 SER L OG  1 
ATOM   8138  N N   . GLU C 3 129 ? 123.396 162.838 162.420 1.00 325.23 ? 129 GLU L N   1 
ATOM   8139  C CA  . GLU C 3 129 ? 124.313 162.264 161.439 1.00 308.97 ? 129 GLU L CA  1 
ATOM   8140  C C   . GLU C 3 129 ? 123.811 162.483 160.010 1.00 282.16 ? 129 GLU L C   1 
ATOM   8141  O O   . GLU C 3 129 ? 124.617 162.772 159.124 1.00 378.62 ? 129 GLU L O   1 
ATOM   8142  C CB  . GLU C 3 129 ? 124.531 160.762 161.660 1.00 287.67 ? 129 GLU L CB  1 
ATOM   8143  C CG  . GLU C 3 129 ? 125.002 160.410 163.064 1.00 362.48 ? 129 GLU L CG  1 
ATOM   8144  C CD  . GLU C 3 129 ? 123.913 159.970 164.029 1.00 441.33 ? 129 GLU L CD  1 
ATOM   8145  O OE1 . GLU C 3 129 ? 122.778 160.493 163.927 1.00 499.06 ? 129 GLU L OE1 1 
ATOM   8146  O OE2 . GLU C 3 129 ? 124.200 159.110 164.882 1.00 487.24 ? 129 GLU L OE2 1 
ATOM   8147  N N   . GLN C 3 130 ? 122.497 162.343 159.787 1.00 242.56 ? 130 GLN L N   1 
ATOM   8148  C CA  . GLN C 3 130 ? 121.906 162.492 158.461 1.00 326.54 ? 130 GLN L CA  1 
ATOM   8149  C C   . GLN C 3 130 ? 122.115 163.907 157.913 1.00 307.96 ? 130 GLN L C   1 
ATOM   8150  O O   . GLN C 3 130 ? 122.286 164.070 156.713 1.00 283.38 ? 130 GLN L O   1 
ATOM   8151  C CB  . GLN C 3 130 ? 120.410 162.163 158.456 1.00 346.46 ? 130 GLN L CB  1 
ATOM   8152  C CG  . GLN C 3 130 ? 119.893 161.852 157.058 1.00 333.41 ? 130 GLN L CG  1 
ATOM   8153  C CD  . GLN C 3 130 ? 118.400 161.689 156.947 1.00 279.55 ? 130 GLN L CD  1 
ATOM   8154  O OE1 . GLN C 3 130 ? 117.649 161.866 157.907 1.00 220.78 ? 130 GLN L OE1 1 
ATOM   8155  N NE2 . GLN C 3 130 ? 117.972 161.342 155.743 1.00 247.26 ? 130 GLN L NE2 1 
ATOM   8156  N N   . LEU C 3 131 ? 122.127 164.920 158.788 1.00 298.19 ? 131 LEU L N   1 
ATOM   8157  C CA  . LEU C 3 131 ? 122.303 166.317 158.403 1.00 337.73 ? 131 LEU L CA  1 
ATOM   8158  C C   . LEU C 3 131 ? 123.657 166.570 157.719 1.00 390.82 ? 131 LEU L C   1 
ATOM   8159  O O   . LEU C 3 131 ? 123.824 167.602 157.081 1.00 392.19 ? 131 LEU L O   1 
ATOM   8160  C CB  . LEU C 3 131 ? 122.161 167.190 159.659 1.00 337.68 ? 131 LEU L CB  1 
ATOM   8161  C CG  . LEU C 3 131 ? 120.825 167.114 160.405 1.00 316.40 ? 131 LEU L CG  1 
ATOM   8162  C CD1 . LEU C 3 131 ? 120.832 168.004 161.642 1.00 334.04 ? 131 LEU L CD1 1 
ATOM   8163  C CD2 . LEU C 3 131 ? 119.662 167.485 159.500 1.00 324.25 ? 131 LEU L CD2 1 
ATOM   8164  N N   . THR C 3 132 ? 124.630 165.648 157.837 1.00 397.53 ? 132 THR L N   1 
ATOM   8165  C CA  . THR C 3 132 ? 125.879 165.720 157.084 1.00 360.64 ? 132 THR L CA  1 
ATOM   8166  C C   . THR C 3 132 ? 125.681 165.468 155.581 1.00 358.65 ? 132 THR L C   1 
ATOM   8167  O O   . THR C 3 132 ? 126.522 165.901 154.793 1.00 404.96 ? 132 THR L O   1 
ATOM   8168  C CB  . THR C 3 132 ? 126.932 164.742 157.634 1.00 344.17 ? 132 THR L CB  1 
ATOM   8169  O OG1 . THR C 3 132 ? 126.511 163.396 157.385 1.00 307.67 ? 132 THR L OG1 1 
ATOM   8170  C CG2 . THR C 3 132 ? 127.213 164.952 159.111 1.00 310.17 ? 132 THR L CG2 1 
ATOM   8171  N N   . SER C 3 133 ? 124.588 164.786 155.186 1.00 330.21 ? 133 SER L N   1 
ATOM   8172  C CA  . SER C 3 133 ? 124.395 164.258 153.840 1.00 350.76 ? 133 SER L CA  1 
ATOM   8173  C C   . SER C 3 133 ? 123.930 165.296 152.812 1.00 387.13 ? 133 SER L C   1 
ATOM   8174  O O   . SER C 3 133 ? 123.888 164.975 151.625 1.00 382.64 ? 133 SER L O   1 
ATOM   8175  C CB  . SER C 3 133 ? 123.400 163.122 153.876 1.00 355.18 ? 133 SER L CB  1 
ATOM   8176  O OG  . SER C 3 133 ? 122.083 163.603 154.124 1.00 333.49 ? 133 SER L OG  1 
ATOM   8177  N N   . GLY C 3 134 ? 123.562 166.515 153.241 1.00 415.63 ? 134 GLY L N   1 
ATOM   8178  C CA  . GLY C 3 134 ? 122.860 167.449 152.374 1.00 433.30 ? 134 GLY L CA  1 
ATOM   8179  C C   . GLY C 3 134 ? 121.355 167.180 152.273 1.00 394.96 ? 134 GLY L C   1 
ATOM   8180  O O   . GLY C 3 134 ? 120.654 167.963 151.633 1.00 396.83 ? 134 GLY L O   1 
ATOM   8181  N N   . GLY C 3 135 ? 120.863 166.095 152.904 1.00 349.56 ? 135 GLY L N   1 
ATOM   8182  C CA  . GLY C 3 135 ? 119.439 165.821 153.038 1.00 338.74 ? 135 GLY L CA  1 
ATOM   8183  C C   . GLY C 3 135 ? 119.047 165.562 154.493 1.00 334.82 ? 135 GLY L C   1 
ATOM   8184  O O   . GLY C 3 135 ? 119.909 165.480 155.372 1.00 266.98 ? 135 GLY L O   1 
ATOM   8185  N N   . ALA C 3 136 ? 117.728 165.447 154.717 1.00 343.11 ? 136 ALA L N   1 
ATOM   8186  C CA  . ALA C 3 136 ? 117.148 165.129 156.015 1.00 304.13 ? 136 ALA L CA  1 
ATOM   8187  C C   . ALA C 3 136 ? 115.814 164.413 155.820 1.00 264.30 ? 136 ALA L C   1 
ATOM   8188  O O   . ALA C 3 136 ? 115.084 164.721 154.874 1.00 221.02 ? 136 ALA L O   1 
ATOM   8189  C CB  . ALA C 3 136 ? 116.966 166.386 156.812 1.00 263.75 ? 136 ALA L CB  1 
ATOM   8190  N N   . SER C 3 137 ? 115.510 163.455 156.708 1.00 259.19 ? 137 SER L N   1 
ATOM   8191  C CA  . SER C 3 137 ? 114.260 162.715 156.646 1.00 226.32 ? 137 SER L CA  1 
ATOM   8192  C C   . SER C 3 137 ? 113.572 162.779 158.004 1.00 223.01 ? 137 SER L C   1 
ATOM   8193  O O   . SER C 3 137 ? 114.134 162.296 158.980 1.00 219.47 ? 137 SER L O   1 
ATOM   8194  C CB  . SER C 3 137 ? 114.455 161.270 156.234 1.00 274.72 ? 137 SER L CB  1 
ATOM   8195  O OG  . SER C 3 137 ? 115.009 161.160 154.933 1.00 276.45 ? 137 SER L OG  1 
ATOM   8196  N N   . VAL C 3 138 ? 112.354 163.338 158.022 1.00 219.97 ? 138 VAL L N   1 
ATOM   8197  C CA  . VAL C 3 138 ? 111.502 163.395 159.197 1.00 229.01 ? 138 VAL L CA  1 
ATOM   8198  C C   . VAL C 3 138 ? 110.584 162.170 159.190 1.00 250.60 ? 138 VAL L C   1 
ATOM   8199  O O   . VAL C 3 138 ? 110.053 161.829 158.134 1.00 181.96 ? 138 VAL L O   1 
ATOM   8200  C CB  . VAL C 3 138 ? 110.678 164.691 159.198 1.00 248.22 ? 138 VAL L CB  1 
ATOM   8201  C CG1 . VAL C 3 138 ? 110.002 164.891 160.544 1.00 255.70 ? 138 VAL L CG1 1 
ATOM   8202  C CG2 . VAL C 3 138 ? 111.495 165.925 158.815 1.00 325.57 ? 138 VAL L CG2 1 
ATOM   8203  N N   . VAL C 3 139 ? 110.386 161.526 160.359 1.00 259.99 ? 139 VAL L N   1 
ATOM   8204  C CA  . VAL C 3 139 ? 109.675 160.251 160.456 1.00 228.24 ? 139 VAL L CA  1 
ATOM   8205  C C   . VAL C 3 139 ? 108.634 160.286 161.576 1.00 208.42 ? 139 VAL L C   1 
ATOM   8206  O O   . VAL C 3 139 ? 108.908 160.711 162.690 1.00 169.04 ? 139 VAL L O   1 
ATOM   8207  C CB  . VAL C 3 139 ? 110.633 159.062 160.647 1.00 222.75 ? 139 VAL L CB  1 
ATOM   8208  C CG1 . VAL C 3 139 ? 109.906 157.770 161.041 1.00 210.62 ? 139 VAL L CG1 1 
ATOM   8209  C CG2 . VAL C 3 139 ? 111.463 158.857 159.391 1.00 261.82 ? 139 VAL L CG2 1 
ATOM   8210  N N   . CYS C 3 140 ? 107.433 159.808 161.232 1.00 209.59 ? 140 CYS L N   1 
ATOM   8211  C CA  . CYS C 3 140 ? 106.293 159.734 162.122 1.00 207.01 ? 140 CYS L CA  1 
ATOM   8212  C C   . CYS C 3 140 ? 105.834 158.280 162.183 1.00 184.97 ? 140 CYS L C   1 
ATOM   8213  O O   . CYS C 3 140 ? 105.522 157.689 161.157 1.00 128.38 ? 140 CYS L O   1 
ATOM   8214  C CB  . CYS C 3 140 ? 105.201 160.656 161.589 1.00 251.08 ? 140 CYS L CB  1 
ATOM   8215  S SG  . CYS C 3 140 ? 103.795 160.899 162.692 1.00 233.89 ? 140 CYS L SG  1 
ATOM   8216  N N   . PHE C 3 141 ? 105.792 157.727 163.399 1.00 213.83 ? 141 PHE L N   1 
ATOM   8217  C CA  . PHE C 3 141 ? 105.312 156.377 163.645 1.00 195.34 ? 141 PHE L CA  1 
ATOM   8218  C C   . PHE C 3 141 ? 103.942 156.396 164.307 1.00 203.48 ? 141 PHE L C   1 
ATOM   8219  O O   . PHE C 3 141 ? 103.731 157.100 165.284 1.00 223.72 ? 141 PHE L O   1 
ATOM   8220  C CB  . PHE C 3 141 ? 106.259 155.638 164.583 1.00 168.71 ? 141 PHE L CB  1 
ATOM   8221  C CG  . PHE C 3 141 ? 107.558 155.158 163.984 1.00 192.84 ? 141 PHE L CG  1 
ATOM   8222  C CD1 . PHE C 3 141 ? 107.796 155.088 162.613 1.00 192.07 ? 141 PHE L CD1 1 
ATOM   8223  C CD2 . PHE C 3 141 ? 108.575 154.752 164.833 1.00 187.09 ? 141 PHE L CD2 1 
ATOM   8224  C CE1 . PHE C 3 141 ? 109.011 154.623 162.124 1.00 201.70 ? 141 PHE L CE1 1 
ATOM   8225  C CE2 . PHE C 3 141 ? 109.788 154.304 164.337 1.00 183.31 ? 141 PHE L CE2 1 
ATOM   8226  C CZ  . PHE C 3 141 ? 110.003 154.223 162.982 1.00 186.54 ? 141 PHE L CZ  1 
ATOM   8227  N N   . LEU C 3 142 ? 103.031 155.596 163.753 1.00 188.41 ? 142 LEU L N   1 
ATOM   8228  C CA  . LEU C 3 142 ? 101.692 155.389 164.265 1.00 167.39 ? 142 LEU L CA  1 
ATOM   8229  C C   . LEU C 3 142 ? 101.620 153.920 164.676 1.00 171.55 ? 142 LEU L C   1 
ATOM   8230  O O   . LEU C 3 142 ? 101.687 153.045 163.814 1.00 192.66 ? 142 LEU L O   1 
ATOM   8231  C CB  . LEU C 3 142 ? 100.700 155.697 163.140 1.00 169.09 ? 142 LEU L CB  1 
ATOM   8232  C CG  . LEU C 3 142 ? 100.974 156.931 162.290 1.00 182.05 ? 142 LEU L CG  1 
ATOM   8233  C CD1 . LEU C 3 142 ? 100.015 156.974 161.123 1.00 193.93 ? 142 LEU L CD1 1 
ATOM   8234  C CD2 . LEU C 3 142 ? 100.854 158.197 163.112 1.00 223.65 ? 142 LEU L CD2 1 
ATOM   8235  N N   . ASN C 3 143 ? 101.501 153.636 165.976 1.00 167.74 ? 143 ASN L N   1 
ATOM   8236  C CA  . ASN C 3 143 ? 101.649 152.274 166.473 1.00 192.16 ? 143 ASN L CA  1 
ATOM   8237  C C   . ASN C 3 143 ? 100.330 151.767 167.054 1.00 164.90 ? 143 ASN L C   1 
ATOM   8238  O O   . ASN C 3 143 ? 99.617  152.507 167.735 1.00 229.00 ? 143 ASN L O   1 
ATOM   8239  C CB  . ASN C 3 143 ? 102.766 152.149 167.514 1.00 225.24 ? 143 ASN L CB  1 
ATOM   8240  C CG  . ASN C 3 143 ? 104.134 152.477 166.956 1.00 248.27 ? 143 ASN L CG  1 
ATOM   8241  O OD1 . ASN C 3 143 ? 104.468 153.651 166.796 1.00 192.18 ? 143 ASN L OD1 1 
ATOM   8242  N ND2 . ASN C 3 143 ? 104.922 151.450 166.666 1.00 250.12 ? 143 ASN L ND2 1 
ATOM   8243  N N   . ASN C 3 144 ? 100.048 150.487 166.764 1.00 188.80 ? 144 ASN L N   1 
ATOM   8244  C CA  . ASN C 3 144 ? 99.102  149.648 167.483 1.00 202.59 ? 144 ASN L CA  1 
ATOM   8245  C C   . ASN C 3 144 ? 97.674  150.188 167.391 1.00 193.45 ? 144 ASN L C   1 
ATOM   8246  O O   . ASN C 3 144 ? 97.110  150.640 168.400 1.00 259.03 ? 144 ASN L O   1 
ATOM   8247  C CB  . ASN C 3 144 ? 99.493  149.464 168.954 1.00 188.61 ? 144 ASN L CB  1 
ATOM   8248  C CG  . ASN C 3 144 ? 100.817 148.768 169.113 1.00 227.53 ? 144 ASN L CG  1 
ATOM   8249  O OD1 . ASN C 3 144 ? 101.763 149.387 169.588 1.00 215.98 ? 144 ASN L OD1 1 
ATOM   8250  N ND2 . ASN C 3 144 ? 100.879 147.503 168.719 1.00 318.69 ? 144 ASN L ND2 1 
ATOM   8251  N N   . PHE C 3 145 ? 97.097  150.132 166.183 1.00 151.34 ? 145 PHE L N   1 
ATOM   8252  C CA  . PHE C 3 145 ? 95.738  150.593 165.962 1.00 181.78 ? 145 PHE L CA  1 
ATOM   8253  C C   . PHE C 3 145 ? 94.939  149.554 165.177 1.00 176.99 ? 145 PHE L C   1 
ATOM   8254  O O   . PHE C 3 145 ? 95.494  148.612 164.630 1.00 186.22 ? 145 PHE L O   1 
ATOM   8255  C CB  . PHE C 3 145 ? 95.782  151.972 165.291 1.00 168.70 ? 145 PHE L CB  1 
ATOM   8256  C CG  . PHE C 3 145 ? 96.424  151.996 163.944 1.00 140.03 ? 145 PHE L CG  1 
ATOM   8257  C CD1 . PHE C 3 145 ? 95.698  151.644 162.810 1.00 195.57 ? 145 PHE L CD1 1 
ATOM   8258  C CD2 . PHE C 3 145 ? 97.737  152.369 163.814 1.00 138.36 ? 145 PHE L CD2 1 
ATOM   8259  C CE1 . PHE C 3 145 ? 96.283  151.653 161.554 1.00 194.67 ? 145 PHE L CE1 1 
ATOM   8260  C CE2 . PHE C 3 145 ? 98.317  152.387 162.553 1.00 199.39 ? 145 PHE L CE2 1 
ATOM   8261  C CZ  . PHE C 3 145 ? 97.596  152.027 161.431 1.00 189.12 ? 145 PHE L CZ  1 
ATOM   8262  N N   . TYR C 3 146 ? 93.618  149.755 165.130 1.00 185.33 ? 146 TYR L N   1 
ATOM   8263  C CA  . TYR C 3 146 ? 92.722  148.943 164.323 1.00 168.66 ? 146 TYR L CA  1 
ATOM   8264  C C   . TYR C 3 146 ? 91.493  149.781 163.993 1.00 159.13 ? 146 TYR L C   1 
ATOM   8265  O O   . TYR C 3 146 ? 91.046  150.511 164.867 1.00 147.33 ? 146 TYR L O   1 
ATOM   8266  C CB  . TYR C 3 146 ? 92.281  147.662 165.056 1.00 165.48 ? 146 TYR L CB  1 
ATOM   8267  C CG  . TYR C 3 146 ? 91.530  146.727 164.116 1.00 140.19 ? 146 TYR L CG  1 
ATOM   8268  C CD1 . TYR C 3 146 ? 92.200  145.815 163.316 1.00 181.95 ? 146 TYR L CD1 1 
ATOM   8269  C CD2 . TYR C 3 146 ? 90.158  146.783 163.986 1.00 163.74 ? 146 TYR L CD2 1 
ATOM   8270  C CE1 . TYR C 3 146 ? 91.531  144.969 162.442 1.00 215.63 ? 146 TYR L CE1 1 
ATOM   8271  C CE2 . TYR C 3 146 ? 89.475  145.951 163.111 1.00 184.22 ? 146 TYR L CE2 1 
ATOM   8272  C CZ  . TYR C 3 146 ? 90.160  145.040 162.333 1.00 209.21 ? 146 TYR L CZ  1 
ATOM   8273  O OH  . TYR C 3 146 ? 89.498  144.216 161.472 1.00 306.32 ? 146 TYR L OH  1 
ATOM   8274  N N   . PRO C 3 147 ? 90.858  149.707 162.797 1.00 149.83 ? 147 PRO L N   1 
ATOM   8275  C CA  . PRO C 3 147 ? 91.304  148.924 161.647 1.00 155.86 ? 147 PRO L CA  1 
ATOM   8276  C C   . PRO C 3 147 ? 92.366  149.646 160.835 1.00 179.18 ? 147 PRO L C   1 
ATOM   8277  O O   . PRO C 3 147 ? 92.792  150.746 161.207 1.00 190.40 ? 147 PRO L O   1 
ATOM   8278  C CB  . PRO C 3 147 ? 89.997  148.772 160.847 1.00 206.52 ? 147 PRO L CB  1 
ATOM   8279  C CG  . PRO C 3 147 ? 89.293  150.083 161.067 1.00 224.39 ? 147 PRO L CG  1 
ATOM   8280  C CD  . PRO C 3 147 ? 89.592  150.403 162.511 1.00 198.01 ? 147 PRO L CD  1 
ATOM   8281  N N   . LYS C 3 148 ? 92.756  148.984 159.728 1.00 199.30 ? 148 LYS L N   1 
ATOM   8282  C CA  . LYS C 3 148 ? 93.846  149.382 158.847 1.00 217.91 ? 148 LYS L CA  1 
ATOM   8283  C C   . LYS C 3 148 ? 93.683  150.799 158.267 1.00 214.26 ? 148 LYS L C   1 
ATOM   8284  O O   . LYS C 3 148 ? 94.684  151.484 158.079 1.00 189.85 ? 148 LYS L O   1 
ATOM   8285  C CB  . LYS C 3 148 ? 93.989  148.346 157.726 1.00 183.51 ? 148 LYS L CB  1 
ATOM   8286  C CG  . LYS C 3 148 ? 95.182  148.576 156.812 1.00 186.70 ? 148 LYS L CG  1 
ATOM   8287  C CD  . LYS C 3 148 ? 95.398  147.483 155.762 1.00 224.59 ? 148 LYS L CD  1 
ATOM   8288  C CE  . LYS C 3 148 ? 96.636  147.700 154.902 1.00 237.64 ? 148 LYS L CE  1 
ATOM   8289  N NZ  . LYS C 3 148 ? 97.469  146.479 154.685 1.00 210.59 ? 148 LYS L NZ  1 
ATOM   8290  N N   . ASP C 3 149 ? 92.457  151.258 157.982 1.00 221.05 ? 149 ASP L N   1 
ATOM   8291  C CA  . ASP C 3 149 ? 92.251  152.543 157.322 1.00 243.76 ? 149 ASP L CA  1 
ATOM   8292  C C   . ASP C 3 149 ? 92.701  153.703 158.212 1.00 218.93 ? 149 ASP L C   1 
ATOM   8293  O O   . ASP C 3 149 ? 92.238  153.816 159.348 1.00 182.35 ? 149 ASP L O   1 
ATOM   8294  C CB  . ASP C 3 149 ? 90.784  152.765 156.926 1.00 324.61 ? 149 ASP L CB  1 
ATOM   8295  C CG  . ASP C 3 149 ? 90.321  152.089 155.643 1.00 381.87 ? 149 ASP L CG  1 
ATOM   8296  O OD1 . ASP C 3 149 ? 91.139  151.408 154.982 1.00 419.43 ? 149 ASP L OD1 1 
ATOM   8297  O OD2 . ASP C 3 149 ? 89.129  152.253 155.307 1.00 384.10 ? 149 ASP L OD2 1 
ATOM   8298  N N   . ILE C 3 150 ? 93.589  154.558 157.659 1.00 207.61 ? 150 ILE L N   1 
ATOM   8299  C CA  . ILE C 3 150 ? 94.149  155.723 158.341 1.00 204.23 ? 150 ILE L CA  1 
ATOM   8300  C C   . ILE C 3 150 ? 94.646  156.726 157.300 1.00 207.32 ? 150 ILE L C   1 
ATOM   8301  O O   . ILE C 3 150 ? 94.870  156.337 156.153 1.00 213.96 ? 150 ILE L O   1 
ATOM   8302  C CB  . ILE C 3 150 ? 95.263  155.260 159.298 1.00 184.14 ? 150 ILE L CB  1 
ATOM   8303  C CG1 . ILE C 3 150 ? 95.693  156.339 160.288 1.00 170.73 ? 150 ILE L CG1 1 
ATOM   8304  C CG2 . ILE C 3 150 ? 96.465  154.730 158.544 1.00 226.25 ? 150 ILE L CG2 1 
ATOM   8305  C CD1 . ILE C 3 150 ? 96.530  155.771 161.435 1.00 186.72 ? 150 ILE L CD1 1 
ATOM   8306  N N   . ASN C 3 151 ? 94.800  158.009 157.684 1.00 230.16 ? 151 ASN L N   1 
ATOM   8307  C CA  . ASN C 3 151 ? 95.484  158.972 156.826 1.00 299.95 ? 151 ASN L CA  1 
ATOM   8308  C C   . ASN C 3 151 ? 96.280  159.961 157.680 1.00 260.66 ? 151 ASN L C   1 
ATOM   8309  O O   . ASN C 3 151 ? 96.000  160.153 158.865 1.00 186.48 ? 151 ASN L O   1 
ATOM   8310  C CB  . ASN C 3 151 ? 94.524  159.628 155.811 1.00 364.88 ? 151 ASN L CB  1 
ATOM   8311  C CG  . ASN C 3 151 ? 93.429  160.511 156.386 1.00 373.76 ? 151 ASN L CG  1 
ATOM   8312  O OD1 . ASN C 3 151 ? 93.715  161.388 157.193 1.00 388.49 ? 151 ASN L OD1 1 
ATOM   8313  N ND2 . ASN C 3 151 ? 92.180  160.307 155.979 1.00 354.15 ? 151 ASN L ND2 1 
ATOM   8314  N N   . VAL C 3 152 ? 97.283  160.575 157.029 1.00 257.02 ? 152 VAL L N   1 
ATOM   8315  C CA  . VAL C 3 152 ? 98.270  161.420 157.682 1.00 244.44 ? 152 VAL L CA  1 
ATOM   8316  C C   . VAL C 3 152 ? 98.383  162.743 156.931 1.00 286.40 ? 152 VAL L C   1 
ATOM   8317  O O   . VAL C 3 152 ? 98.482  162.750 155.702 1.00 270.59 ? 152 VAL L O   1 
ATOM   8318  C CB  . VAL C 3 152 ? 99.642  160.735 157.745 1.00 229.61 ? 152 VAL L CB  1 
ATOM   8319  C CG1 . VAL C 3 152 ? 100.661 161.574 158.515 1.00 272.92 ? 152 VAL L CG1 1 
ATOM   8320  C CG2 . VAL C 3 152 ? 99.528  159.346 158.337 1.00 248.44 ? 152 VAL L CG2 1 
ATOM   8321  N N   . LYS C 3 153 ? 98.373  163.844 157.702 1.00 320.10 ? 153 LYS L N   1 
ATOM   8322  C CA  . LYS C 3 153 ? 98.715  165.174 157.224 1.00 328.12 ? 153 LYS L CA  1 
ATOM   8323  C C   . LYS C 3 153 ? 100.088 165.567 157.776 1.00 256.00 ? 153 LYS L C   1 
ATOM   8324  O O   . LYS C 3 153 ? 100.345 165.477 158.976 1.00 162.70 ? 153 LYS L O   1 
ATOM   8325  C CB  . LYS C 3 153 ? 97.637  166.184 157.637 1.00 358.51 ? 153 LYS L CB  1 
ATOM   8326  C CG  . LYS C 3 153 ? 96.557  166.462 156.597 1.00 374.47 ? 153 LYS L CG  1 
ATOM   8327  C CD  . LYS C 3 153 ? 95.700  165.260 156.258 1.00 388.07 ? 153 LYS L CD  1 
ATOM   8328  C CE  . LYS C 3 153 ? 94.612  165.557 155.246 1.00 386.76 ? 153 LYS L CE  1 
ATOM   8329  N NZ  . LYS C 3 153 ? 95.163  165.894 153.909 1.00 365.13 ? 153 LYS L NZ  1 
ATOM   8330  N N   . TRP C 3 154 ? 100.977 166.006 156.880 1.00 210.99 ? 154 TRP L N   1 
ATOM   8331  C CA  . TRP C 3 154 ? 102.192 166.684 157.278 1.00 217.30 ? 154 TRP L CA  1 
ATOM   8332  C C   . TRP C 3 154 ? 102.010 168.195 157.131 1.00 280.63 ? 154 TRP L C   1 
ATOM   8333  O O   . TRP C 3 154 ? 101.576 168.670 156.078 1.00 340.41 ? 154 TRP L O   1 
ATOM   8334  C CB  . TRP C 3 154 ? 103.356 166.177 156.426 1.00 262.27 ? 154 TRP L CB  1 
ATOM   8335  C CG  . TRP C 3 154 ? 103.878 164.836 156.871 1.00 246.24 ? 154 TRP L CG  1 
ATOM   8336  C CD1 . TRP C 3 154 ? 103.494 163.623 156.391 1.00 245.29 ? 154 TRP L CD1 1 
ATOM   8337  C CD2 . TRP C 3 154 ? 104.881 164.576 157.877 1.00 211.22 ? 154 TRP L CD2 1 
ATOM   8338  N NE1 . TRP C 3 154 ? 104.189 162.630 157.021 1.00 258.43 ? 154 TRP L NE1 1 
ATOM   8339  C CE2 . TRP C 3 154 ? 105.045 163.180 157.936 1.00 220.36 ? 154 TRP L CE2 1 
ATOM   8340  C CE3 . TRP C 3 154 ? 105.654 165.373 158.725 1.00 223.95 ? 154 TRP L CE3 1 
ATOM   8341  C CZ2 . TRP C 3 154 ? 105.946 162.571 158.808 1.00 246.40 ? 154 TRP L CZ2 1 
ATOM   8342  C CZ3 . TRP C 3 154 ? 106.545 164.776 159.582 1.00 204.07 ? 154 TRP L CZ3 1 
ATOM   8343  C CH2 . TRP C 3 154 ? 106.688 163.393 159.623 1.00 249.74 ? 154 TRP L CH2 1 
ATOM   8344  N N   . LYS C 3 155 ? 102.341 168.933 158.202 1.00 282.85 ? 155 LYS L N   1 
ATOM   8345  C CA  . LYS C 3 155 ? 102.345 170.387 158.197 1.00 292.77 ? 155 LYS L CA  1 
ATOM   8346  C C   . LYS C 3 155 ? 103.755 170.886 158.526 1.00 276.08 ? 155 LYS L C   1 
ATOM   8347  O O   . LYS C 3 155 ? 104.455 170.322 159.370 1.00 207.76 ? 155 LYS L O   1 
ATOM   8348  C CB  . LYS C 3 155 ? 101.287 170.937 159.165 1.00 342.86 ? 155 LYS L CB  1 
ATOM   8349  C CG  . LYS C 3 155 ? 99.965  171.370 158.533 1.00 373.49 ? 155 LYS L CG  1 
ATOM   8350  C CD  . LYS C 3 155 ? 99.110  170.230 158.003 1.00 361.01 ? 155 LYS L CD  1 
ATOM   8351  C CE  . LYS C 3 155 ? 97.752  170.663 157.486 1.00 324.33 ? 155 LYS L CE  1 
ATOM   8352  N NZ  . LYS C 3 155 ? 96.799  170.956 158.580 1.00 330.83 ? 155 LYS L NZ  1 
ATOM   8353  N N   . ILE C 3 156 ? 104.145 171.967 157.839 1.00 324.06 ? 156 ILE L N   1 
ATOM   8354  C CA  . ILE C 3 156 ? 105.485 172.530 157.903 1.00 339.76 ? 156 ILE L CA  1 
ATOM   8355  C C   . ILE C 3 156 ? 105.310 174.055 157.951 1.00 381.32 ? 156 ILE L C   1 
ATOM   8356  O O   . ILE C 3 156 ? 104.879 174.667 156.969 1.00 418.70 ? 156 ILE L O   1 
ATOM   8357  C CB  . ILE C 3 156 ? 106.354 171.987 156.737 1.00 324.32 ? 156 ILE L CB  1 
ATOM   8358  C CG1 . ILE C 3 156 ? 107.692 172.725 156.613 1.00 399.45 ? 156 ILE L CG1 1 
ATOM   8359  C CG2 . ILE C 3 156 ? 105.609 171.982 155.402 1.00 298.74 ? 156 ILE L CG2 1 
ATOM   8360  C CD1 . ILE C 3 156 ? 108.668 172.085 155.649 1.00 416.04 ? 156 ILE L CD1 1 
ATOM   8361  N N   . ASP C 3 157 ? 105.617 174.653 159.119 1.00 325.86 ? 157 ASP L N   1 
ATOM   8362  C CA  . ASP C 3 157 ? 105.271 176.031 159.454 1.00 323.93 ? 157 ASP L CA  1 
ATOM   8363  C C   . ASP C 3 157 ? 103.803 176.342 159.124 1.00 343.57 ? 157 ASP L C   1 
ATOM   8364  O O   . ASP C 3 157 ? 103.488 177.455 158.697 1.00 381.27 ? 157 ASP L O   1 
ATOM   8365  C CB  . ASP C 3 157 ? 106.263 176.991 158.779 1.00 324.12 ? 157 ASP L CB  1 
ATOM   8366  C CG  . ASP C 3 157 ? 107.685 176.959 159.324 1.00 302.56 ? 157 ASP L CG  1 
ATOM   8367  O OD1 . ASP C 3 157 ? 107.932 176.297 160.348 1.00 303.93 ? 157 ASP L OD1 1 
ATOM   8368  O OD2 . ASP C 3 157 ? 108.550 177.608 158.718 1.00 280.17 ? 157 ASP L OD2 1 
ATOM   8369  N N   . GLY C 3 158 ? 102.901 175.363 159.320 1.00 351.39 ? 158 GLY L N   1 
ATOM   8370  C CA  . GLY C 3 158 ? 101.483 175.534 159.018 1.00 367.76 ? 158 GLY L CA  1 
ATOM   8371  C C   . GLY C 3 158 ? 101.069 175.151 157.592 1.00 372.79 ? 158 GLY L C   1 
ATOM   8372  O O   . GLY C 3 158 ? 99.891  174.863 157.369 1.00 316.50 ? 158 GLY L O   1 
ATOM   8373  N N   . SER C 3 159 ? 102.011 175.149 156.632 1.00 378.90 ? 159 SER L N   1 
ATOM   8374  C CA  . SER C 3 159 ? 101.720 174.791 155.250 1.00 378.13 ? 159 SER L CA  1 
ATOM   8375  C C   . SER C 3 159 ? 101.554 173.274 155.124 1.00 352.29 ? 159 SER L C   1 
ATOM   8376  O O   . SER C 3 159 ? 102.348 172.527 155.693 1.00 313.07 ? 159 SER L O   1 
ATOM   8377  C CB  . SER C 3 159 ? 102.803 175.308 154.333 1.00 411.29 ? 159 SER L CB  1 
ATOM   8378  O OG  . SER C 3 159 ? 102.474 175.067 152.973 1.00 444.28 ? 159 SER L OG  1 
ATOM   8379  N N   . GLU C 3 160 ? 100.530 172.827 154.373 1.00 339.98 ? 160 GLU L N   1 
ATOM   8380  C CA  . GLU C 3 160 ? 100.259 171.408 154.164 1.00 333.80 ? 160 GLU L CA  1 
ATOM   8381  C C   . GLU C 3 160 ? 101.201 170.851 153.094 1.00 308.30 ? 160 GLU L C   1 
ATOM   8382  O O   . GLU C 3 160 ? 101.330 171.436 152.015 1.00 324.01 ? 160 GLU L O   1 
ATOM   8383  C CB  . GLU C 3 160 ? 98.803  171.186 153.742 1.00 376.75 ? 160 GLU L CB  1 
ATOM   8384  C CG  . GLU C 3 160 ? 98.401  169.717 153.679 1.00 416.31 ? 160 GLU L CG  1 
ATOM   8385  C CD  . GLU C 3 160 ? 96.945  169.435 153.347 1.00 478.96 ? 160 GLU L CD  1 
ATOM   8386  O OE1 . GLU C 3 160 ? 96.242  170.360 152.888 1.00 511.18 ? 160 GLU L OE1 1 
ATOM   8387  O OE2 . GLU C 3 160 ? 96.518  168.284 153.555 1.00 523.21 ? 160 GLU L OE2 1 
ATOM   8388  N N   . ARG C 3 161 ? 101.841 169.705 153.396 1.00 303.83 ? 161 ARG L N   1 
ATOM   8389  C CA  . ARG C 3 161 ? 102.834 169.090 152.527 1.00 287.59 ? 161 ARG L CA  1 
ATOM   8390  C C   . ARG C 3 161 ? 102.282 167.793 151.926 1.00 292.93 ? 161 ARG L C   1 
ATOM   8391  O O   . ARG C 3 161 ? 101.787 166.922 152.646 1.00 278.77 ? 161 ARG L O   1 
ATOM   8392  C CB  . ARG C 3 161 ? 104.103 168.831 153.338 1.00 284.11 ? 161 ARG L CB  1 
ATOM   8393  C CG  . ARG C 3 161 ? 105.281 168.302 152.536 1.00 314.63 ? 161 ARG L CG  1 
ATOM   8394  C CD  . ARG C 3 161 ? 105.745 169.139 151.357 1.00 285.80 ? 161 ARG L CD  1 
ATOM   8395  N NE  . ARG C 3 161 ? 106.948 168.510 150.806 1.00 318.83 ? 161 ARG L NE  1 
ATOM   8396  C CZ  . ARG C 3 161 ? 108.094 169.123 150.492 1.00 363.59 ? 161 ARG L CZ  1 
ATOM   8397  N NH1 . ARG C 3 161 ? 109.115 168.413 150.033 1.00 383.52 ? 161 ARG L NH1 1 
ATOM   8398  N NH2 . ARG C 3 161 ? 108.235 170.434 150.635 1.00 375.29 ? 161 ARG L NH2 1 
ATOM   8399  N N   . GLN C 3 162 ? 102.378 167.673 150.592 1.00 273.54 ? 162 GLN L N   1 
ATOM   8400  C CA  . GLN C 3 162 ? 101.875 166.513 149.850 1.00 296.18 ? 162 GLN L CA  1 
ATOM   8401  C C   . GLN C 3 162 ? 102.865 165.990 148.793 1.00 282.23 ? 162 GLN L C   1 
ATOM   8402  O O   . GLN C 3 162 ? 102.626 164.909 148.243 1.00 212.31 ? 162 GLN L O   1 
ATOM   8403  C CB  . GLN C 3 162 ? 100.509 166.854 149.238 1.00 356.12 ? 162 GLN L CB  1 
ATOM   8404  C CG  . GLN C 3 162 ? 100.517 168.030 148.257 1.00 435.12 ? 162 GLN L CG  1 
ATOM   8405  C CD  . GLN C 3 162 ? 99.193  168.751 148.120 1.00 467.24 ? 162 GLN L CD  1 
ATOM   8406  O OE1 . GLN C 3 162 ? 98.161  168.327 148.640 1.00 465.93 ? 162 GLN L OE1 1 
ATOM   8407  N NE2 . GLN C 3 162 ? 99.212  169.868 147.407 1.00 475.71 ? 162 GLN L NE2 1 
ATOM   8408  N N   . ASN C 3 163 ? 103.958 166.729 148.506 1.00 320.07 ? 163 ASN L N   1 
ATOM   8409  C CA  . ASN C 3 163 ? 105.116 166.219 147.780 1.00 361.25 ? 163 ASN L CA  1 
ATOM   8410  C C   . ASN C 3 163 ? 106.055 165.481 148.734 1.00 339.98 ? 163 ASN L C   1 
ATOM   8411  O O   . ASN C 3 163 ? 106.240 165.908 149.876 1.00 318.74 ? 163 ASN L O   1 
ATOM   8412  C CB  . ASN C 3 163 ? 105.905 167.348 147.107 1.00 405.99 ? 163 ASN L CB  1 
ATOM   8413  C CG  . ASN C 3 163 ? 105.116 168.152 146.095 1.00 482.73 ? 163 ASN L CG  1 
ATOM   8414  O OD1 . ASN C 3 163 ? 104.139 167.671 145.522 1.00 547.75 ? 163 ASN L OD1 1 
ATOM   8415  N ND2 . ASN C 3 163 ? 105.541 169.384 145.857 1.00 498.11 ? 163 ASN L ND2 1 
ATOM   8416  N N   . GLY C 3 164 ? 106.657 164.378 148.258 1.00 332.54 ? 164 GLY L N   1 
ATOM   8417  C CA  . GLY C 3 164 ? 107.748 163.712 148.960 1.00 331.02 ? 164 GLY L CA  1 
ATOM   8418  C C   . GLY C 3 164 ? 107.352 163.074 150.293 1.00 285.56 ? 164 GLY L C   1 
ATOM   8419  O O   . GLY C 3 164 ? 108.189 162.992 151.181 1.00 225.83 ? 164 GLY L O   1 
ATOM   8420  N N   . VAL C 3 165 ? 106.088 162.623 150.408 1.00 309.52 ? 165 VAL L N   1 
ATOM   8421  C CA  . VAL C 3 165 ? 105.576 161.878 151.555 1.00 296.14 ? 165 VAL L CA  1 
ATOM   8422  C C   . VAL C 3 165 ? 105.359 160.415 151.146 1.00 303.26 ? 165 VAL L C   1 
ATOM   8423  O O   . VAL C 3 165 ? 104.767 160.147 150.097 1.00 297.91 ? 165 VAL L O   1 
ATOM   8424  C CB  . VAL C 3 165 ? 104.276 162.516 152.091 1.00 299.99 ? 165 VAL L CB  1 
ATOM   8425  C CG1 . VAL C 3 165 ? 103.489 161.605 153.031 1.00 242.13 ? 165 VAL L CG1 1 
ATOM   8426  C CG2 . VAL C 3 165 ? 104.565 163.856 152.749 1.00 314.23 ? 165 VAL L CG2 1 
ATOM   8427  N N   . LEU C 3 166 ? 105.819 159.494 152.009 1.00 280.19 ? 166 LEU L N   1 
ATOM   8428  C CA  . LEU C 3 166 ? 105.723 158.056 151.806 1.00 249.04 ? 166 LEU L CA  1 
ATOM   8429  C C   . LEU C 3 166 ? 105.164 157.391 153.059 1.00 251.28 ? 166 LEU L C   1 
ATOM   8430  O O   . LEU C 3 166 ? 105.377 157.886 154.164 1.00 228.20 ? 166 LEU L O   1 
ATOM   8431  C CB  . LEU C 3 166 ? 107.123 157.523 151.510 1.00 251.31 ? 166 LEU L CB  1 
ATOM   8432  C CG  . LEU C 3 166 ? 107.709 157.975 150.178 1.00 303.22 ? 166 LEU L CG  1 
ATOM   8433  C CD1 . LEU C 3 166 ? 109.166 157.539 150.051 1.00 340.60 ? 166 LEU L CD1 1 
ATOM   8434  C CD2 . LEU C 3 166 ? 106.869 157.439 149.022 1.00 278.25 ? 166 LEU L CD2 1 
ATOM   8435  N N   . ASN C 3 167 ? 104.458 156.271 152.849 1.00 240.07 ? 167 ASN L N   1 
ATOM   8436  C CA  . ASN C 3 167 ? 103.808 155.531 153.915 1.00 200.81 ? 167 ASN L CA  1 
ATOM   8437  C C   . ASN C 3 167 ? 104.064 154.036 153.752 1.00 240.43 ? 167 ASN L C   1 
ATOM   8438  O O   . ASN C 3 167 ? 104.141 153.523 152.632 1.00 234.15 ? 167 ASN L O   1 
ATOM   8439  C CB  . ASN C 3 167 ? 102.299 155.750 153.929 1.00 172.22 ? 167 ASN L CB  1 
ATOM   8440  C CG  . ASN C 3 167 ? 101.905 157.193 154.153 1.00 223.29 ? 167 ASN L CG  1 
ATOM   8441  O OD1 . ASN C 3 167 ? 102.509 157.884 154.969 1.00 189.31 ? 167 ASN L OD1 1 
ATOM   8442  N ND2 . ASN C 3 167 ? 100.890 157.661 153.444 1.00 273.45 ? 167 ASN L ND2 1 
ATOM   8443  N N   . SER C 3 168 ? 104.190 153.344 154.893 1.00 224.79 ? 168 SER L N   1 
ATOM   8444  C CA  . SER C 3 168 ? 104.225 151.892 154.908 1.00 207.67 ? 168 SER L CA  1 
ATOM   8445  C C   . SER C 3 168 ? 103.486 151.357 156.134 1.00 200.24 ? 168 SER L C   1 
ATOM   8446  O O   . SER C 3 168 ? 103.807 151.710 157.257 1.00 169.53 ? 168 SER L O   1 
ATOM   8447  C CB  . SER C 3 168 ? 105.628 151.404 154.882 1.00 220.57 ? 168 SER L CB  1 
ATOM   8448  O OG  . SER C 3 168 ? 105.657 149.982 154.821 1.00 224.32 ? 168 SER L OG  1 
ATOM   8449  N N   . TRP C 3 169 ? 102.505 150.491 155.889 1.00 191.15 ? 169 TRP L N   1 
ATOM   8450  C CA  . TRP C 3 169 ? 101.798 149.775 156.928 1.00 154.03 ? 169 TRP L CA  1 
ATOM   8451  C C   . TRP C 3 169 ? 102.493 148.451 157.179 1.00 177.03 ? 169 TRP L C   1 
ATOM   8452  O O   . TRP C 3 169 ? 102.926 147.812 156.204 1.00 192.20 ? 169 TRP L O   1 
ATOM   8453  C CB  . TRP C 3 169 ? 100.408 149.384 156.447 1.00 223.90 ? 169 TRP L CB  1 
ATOM   8454  C CG  . TRP C 3 169 ? 99.380  150.471 156.399 1.00 193.57 ? 169 TRP L CG  1 
ATOM   8455  C CD1 . TRP C 3 169 ? 98.358  150.588 157.282 1.00 197.15 ? 169 TRP L CD1 1 
ATOM   8456  C CD2 . TRP C 3 169 ? 99.237  151.546 155.455 1.00 180.72 ? 169 TRP L CD2 1 
ATOM   8457  N NE1 . TRP C 3 169 ? 97.580  151.656 156.960 1.00 180.50 ? 169 TRP L NE1 1 
ATOM   8458  C CE2 . TRP C 3 169 ? 98.095  152.267 155.852 1.00 182.30 ? 169 TRP L CE2 1 
ATOM   8459  C CE3 . TRP C 3 169 ? 99.953  151.973 154.332 1.00 236.52 ? 169 TRP L CE3 1 
ATOM   8460  C CZ2 . TRP C 3 169 ? 97.655  153.393 155.163 1.00 264.65 ? 169 TRP L CZ2 1 
ATOM   8461  C CZ3 . TRP C 3 169 ? 99.516  153.086 153.649 1.00 276.74 ? 169 TRP L CZ3 1 
ATOM   8462  C CH2 . TRP C 3 169 ? 98.383  153.788 154.063 1.00 307.39 ? 169 TRP L CH2 1 
ATOM   8463  N N   . THR C 3 170 ? 102.547 148.026 158.452 1.00 118.11 ? 170 THR L N   1 
ATOM   8464  C CA  . THR C 3 170 ? 102.919 146.646 158.702 1.00 129.07 ? 170 THR L CA  1 
ATOM   8465  C C   . THR C 3 170 ? 101.782 145.706 158.327 1.00 154.20 ? 170 THR L C   1 
ATOM   8466  O O   . THR C 3 170 ? 100.623 146.114 158.257 1.00 289.36 ? 170 THR L O   1 
ATOM   8467  C CB  . THR C 3 170 ? 103.280 146.376 160.160 1.00 141.04 ? 170 THR L CB  1 
ATOM   8468  O OG1 . THR C 3 170 ? 102.085 146.452 160.953 1.00 91.84  ? 170 THR L OG1 1 
ATOM   8469  C CG2 . THR C 3 170 ? 104.377 147.298 160.629 1.00 182.41 ? 170 THR L CG2 1 
ATOM   8470  N N   . ASP C 3 171 ? 102.130 144.438 158.120 1.00 171.74 ? 171 ASP L N   1 
ATOM   8471  C CA  . ASP C 3 171 ? 101.184 143.336 158.288 1.00 206.01 ? 171 ASP L CA  1 
ATOM   8472  C C   . ASP C 3 171 ? 100.672 143.342 159.735 1.00 181.21 ? 171 ASP L C   1 
ATOM   8473  O O   . ASP C 3 171 ? 101.316 143.872 160.634 1.00 177.64 ? 171 ASP L O   1 
ATOM   8474  C CB  . ASP C 3 171 ? 101.828 142.012 157.868 1.00 233.33 ? 171 ASP L CB  1 
ATOM   8475  C CG  . ASP C 3 171 ? 102.304 141.989 156.416 1.00 341.96 ? 171 ASP L CG  1 
ATOM   8476  O OD1 . ASP C 3 171 ? 102.053 142.978 155.688 1.00 393.50 ? 171 ASP L OD1 1 
ATOM   8477  O OD2 . ASP C 3 171 ? 102.932 140.975 156.007 1.00 388.33 ? 171 ASP L OD2 1 
ATOM   8478  N N   . GLN C 3 172 ? 99.500  142.766 159.969 1.00 169.78 ? 172 GLN L N   1 
ATOM   8479  C CA  . GLN C 3 172 ? 98.842  142.828 161.268 1.00 169.56 ? 172 GLN L CA  1 
ATOM   8480  C C   . GLN C 3 172 ? 99.611  141.964 162.293 1.00 156.80 ? 172 GLN L C   1 
ATOM   8481  O O   . GLN C 3 172 ? 100.033 140.845 162.000 1.00 169.36 ? 172 GLN L O   1 
ATOM   8482  C CB  . GLN C 3 172 ? 97.412  142.365 160.998 1.00 179.79 ? 172 GLN L CB  1 
ATOM   8483  C CG  . GLN C 3 172 ? 96.420  142.548 162.127 1.00 171.48 ? 172 GLN L CG  1 
ATOM   8484  C CD  . GLN C 3 172 ? 95.014  142.294 161.639 1.00 210.35 ? 172 GLN L CD  1 
ATOM   8485  O OE1 . GLN C 3 172 ? 94.789  142.015 160.464 1.00 262.52 ? 172 GLN L OE1 1 
ATOM   8486  N NE2 . GLN C 3 172 ? 94.035  142.416 162.524 1.00 207.79 ? 172 GLN L NE2 1 
ATOM   8487  N N   . ASP C 3 173 ? 99.804  142.458 163.515 1.00 130.99 ? 173 ASP L N   1 
ATOM   8488  C CA  . ASP C 3 173 ? 100.671 141.824 164.506 1.00 194.53 ? 173 ASP L CA  1 
ATOM   8489  C C   . ASP C 3 173 ? 99.990  140.603 165.118 1.00 176.61 ? 173 ASP L C   1 
ATOM   8490  O O   . ASP C 3 173 ? 98.957  140.745 165.748 1.00 237.75 ? 173 ASP L O   1 
ATOM   8491  C CB  . ASP C 3 173 ? 101.056 142.826 165.613 1.00 308.01 ? 173 ASP L CB  1 
ATOM   8492  C CG  . ASP C 3 173 ? 101.836 142.299 166.816 1.00 347.00 ? 173 ASP L CG  1 
ATOM   8493  O OD1 . ASP C 3 173 ? 102.156 141.081 166.854 1.00 416.38 ? 173 ASP L OD1 1 
ATOM   8494  O OD2 . ASP C 3 173 ? 102.117 143.109 167.731 1.00 318.06 ? 173 ASP L OD2 1 
ATOM   8495  N N   . SER C 3 174 ? 100.589 139.415 164.988 1.00 183.92 ? 174 SER L N   1 
ATOM   8496  C CA  . SER C 3 174 ? 99.991  138.176 165.481 1.00 210.52 ? 174 SER L CA  1 
ATOM   8497  C C   . SER C 3 174 ? 99.791  138.096 167.008 1.00 207.34 ? 174 SER L C   1 
ATOM   8498  O O   . SER C 3 174 ? 99.041  137.242 167.451 1.00 256.75 ? 174 SER L O   1 
ATOM   8499  C CB  . SER C 3 174 ? 100.806 136.999 164.998 1.00 263.01 ? 174 SER L CB  1 
ATOM   8500  O OG  . SER C 3 174 ? 102.171 137.168 165.358 1.00 298.82 ? 174 SER L OG  1 
ATOM   8501  N N   . LYS C 3 175 ? 100.426 138.931 167.843 1.00 254.12 ? 175 LYS L N   1 
ATOM   8502  C CA  . LYS C 3 175 ? 100.198 138.886 169.289 1.00 275.83 ? 175 LYS L CA  1 
ATOM   8503  C C   . LYS C 3 175 ? 98.943  139.662 169.714 1.00 275.75 ? 175 LYS L C   1 
ATOM   8504  O O   . LYS C 3 175 ? 98.300  139.287 170.696 1.00 290.30 ? 175 LYS L O   1 
ATOM   8505  C CB  . LYS C 3 175 ? 101.403 139.458 170.042 1.00 319.15 ? 175 LYS L CB  1 
ATOM   8506  C CG  . LYS C 3 175 ? 102.697 138.664 169.919 1.00 350.87 ? 175 LYS L CG  1 
ATOM   8507  C CD  . LYS C 3 175 ? 103.914 139.361 170.522 1.00 446.68 ? 175 LYS L CD  1 
ATOM   8508  C CE  . LYS C 3 175 ? 104.259 140.711 169.916 1.00 515.72 ? 175 LYS L CE  1 
ATOM   8509  N NZ  . LYS C 3 175 ? 104.450 140.654 168.446 1.00 536.47 ? 175 LYS L NZ  1 
ATOM   8510  N N   . ASP C 3 176 ? 98.610  140.745 168.989 1.00 237.93 ? 176 ASP L N   1 
ATOM   8511  C CA  . ASP C 3 176 ? 97.612  141.721 169.408 1.00 228.70 ? 176 ASP L CA  1 
ATOM   8512  C C   . ASP C 3 176 ? 96.639  142.119 168.297 1.00 205.98 ? 176 ASP L C   1 
ATOM   8513  O O   . ASP C 3 176 ? 95.704  142.873 168.562 1.00 237.54 ? 176 ASP L O   1 
ATOM   8514  C CB  . ASP C 3 176 ? 98.351  142.955 169.939 1.00 283.17 ? 176 ASP L CB  1 
ATOM   8515  C CG  . ASP C 3 176 ? 97.599  143.836 170.935 1.00 398.40 ? 176 ASP L CG  1 
ATOM   8516  O OD1 . ASP C 3 176 ? 96.453  143.499 171.312 1.00 463.24 ? 176 ASP L OD1 1 
ATOM   8517  O OD2 . ASP C 3 176 ? 98.181  144.868 171.339 1.00 418.77 ? 176 ASP L OD2 1 
ATOM   8518  N N   . SER C 3 177 ? 96.857  141.626 167.065 1.00 203.14 ? 177 SER L N   1 
ATOM   8519  C CA  . SER C 3 177 ? 96.027  141.862 165.894 1.00 162.05 ? 177 SER L CA  1 
ATOM   8520  C C   . SER C 3 177 ? 95.895  143.348 165.532 1.00 157.46 ? 177 SER L C   1 
ATOM   8521  O O   . SER C 3 177 ? 94.923  143.708 164.868 1.00 214.57 ? 177 SER L O   1 
ATOM   8522  C CB  . SER C 3 177 ? 94.702  141.202 166.090 1.00 178.33 ? 177 SER L CB  1 
ATOM   8523  O OG  . SER C 3 177 ? 94.873  139.829 166.383 1.00 219.83 ? 177 SER L OG  1 
ATOM   8524  N N   . THR C 3 178 ? 96.863  144.204 165.936 1.00 162.28 ? 178 THR L N   1 
ATOM   8525  C CA  . THR C 3 178 ? 96.893  145.609 165.549 1.00 172.34 ? 178 THR L CA  1 
ATOM   8526  C C   . THR C 3 178 ? 97.775  145.840 164.321 1.00 152.07 ? 178 THR L C   1 
ATOM   8527  O O   . THR C 3 178 ? 98.741  145.126 164.101 1.00 201.15 ? 178 THR L O   1 
ATOM   8528  C CB  . THR C 3 178 ? 97.412  146.511 166.673 1.00 195.54 ? 178 THR L CB  1 
ATOM   8529  O OG1 . THR C 3 178 ? 98.754  146.141 167.011 1.00 211.98 ? 178 THR L OG1 1 
ATOM   8530  C CG2 . THR C 3 178 ? 96.500  146.474 167.883 1.00 220.38 ? 178 THR L CG2 1 
ATOM   8531  N N   . TYR C 3 179 ? 97.428  146.858 163.536 1.00 150.02 ? 179 TYR L N   1 
ATOM   8532  C CA  . TYR C 3 179 ? 98.314  147.404 162.529 1.00 149.13 ? 179 TYR L CA  1 
ATOM   8533  C C   . TYR C 3 179 ? 99.212  148.447 163.176 1.00 155.06 ? 179 TYR L C   1 
ATOM   8534  O O   . TYR C 3 179 ? 98.944  148.919 164.286 1.00 202.27 ? 179 TYR L O   1 
ATOM   8535  C CB  . TYR C 3 179 ? 97.532  148.043 161.383 1.00 127.77 ? 179 TYR L CB  1 
ATOM   8536  C CG  . TYR C 3 179 ? 96.726  147.010 160.607 1.00 146.16 ? 179 TYR L CG  1 
ATOM   8537  C CD1 . TYR C 3 179 ? 95.509  146.535 161.054 1.00 168.76 ? 179 TYR L CD1 1 
ATOM   8538  C CD2 . TYR C 3 179 ? 97.193  146.487 159.415 1.00 186.90 ? 179 TYR L CD2 1 
ATOM   8539  C CE1 . TYR C 3 179 ? 94.789  145.587 160.334 1.00 231.19 ? 179 TYR L CE1 1 
ATOM   8540  C CE2 . TYR C 3 179 ? 96.485  145.547 158.680 1.00 168.74 ? 179 TYR L CE2 1 
ATOM   8541  C CZ  . TYR C 3 179 ? 95.272  145.093 159.137 1.00 205.31 ? 179 TYR L CZ  1 
ATOM   8542  O OH  . TYR C 3 179 ? 94.586  144.163 158.414 1.00 261.26 ? 179 TYR L OH  1 
ATOM   8543  N N   . SER C 3 180 ? 100.283 148.792 162.448 1.00 158.71 ? 180 SER L N   1 
ATOM   8544  C CA  . SER C 3 180 ? 101.107 149.970 162.701 1.00 144.65 ? 180 SER L CA  1 
ATOM   8545  C C   . SER C 3 180 ? 101.531 150.561 161.362 1.00 134.36 ? 180 SER L C   1 
ATOM   8546  O O   . SER C 3 180 ? 101.529 149.846 160.358 1.00 111.99 ? 180 SER L O   1 
ATOM   8547  C CB  . SER C 3 180 ? 102.304 149.659 163.568 1.00 172.79 ? 180 SER L CB  1 
ATOM   8548  O OG  . SER C 3 180 ? 101.920 149.254 164.885 1.00 209.83 ? 180 SER L OG  1 
ATOM   8549  N N   . MET C 3 181 ? 101.872 151.860 161.351 1.00 152.55 ? 181 MET L N   1 
ATOM   8550  C CA  . MET C 3 181 ? 102.215 152.539 160.107 1.00 164.96 ? 181 MET L CA  1 
ATOM   8551  C C   . MET C 3 181 ? 103.330 153.555 160.345 1.00 149.61 ? 181 MET L C   1 
ATOM   8552  O O   . MET C 3 181 ? 103.318 154.276 161.323 1.00 152.53 ? 181 MET L O   1 
ATOM   8553  C CB  . MET C 3 181 ? 101.022 153.268 159.478 1.00 158.73 ? 181 MET L CB  1 
ATOM   8554  C CG  . MET C 3 181 ? 101.220 153.488 157.993 1.00 197.42 ? 181 MET L CG  1 
ATOM   8555  S SD  . MET C 3 181 ? 100.038 154.658 157.252 1.00 176.94 ? 181 MET L SD  1 
ATOM   8556  C CE  . MET C 3 181 ? 101.100 156.100 157.414 1.00 315.57 ? 181 MET L CE  1 
ATOM   8557  N N   . SER C 3 182 ? 104.284 153.576 159.412 1.00 163.63 ? 182 SER L N   1 
ATOM   8558  C CA  . SER C 3 182 ? 105.343 154.560 159.335 1.00 143.93 ? 182 SER L CA  1 
ATOM   8559  C C   . SER C 3 182 ? 105.021 155.536 158.214 1.00 176.39 ? 182 SER L C   1 
ATOM   8560  O O   . SER C 3 182 ? 104.606 155.112 157.129 1.00 168.59 ? 182 SER L O   1 
ATOM   8561  C CB  . SER C 3 182 ? 106.636 153.890 159.063 1.00 200.67 ? 182 SER L CB  1 
ATOM   8562  O OG  . SER C 3 182 ? 107.650 154.827 158.720 1.00 312.47 ? 182 SER L OG  1 
ATOM   8563  N N   . SER C 3 183 ? 105.215 156.827 158.515 1.00 195.00 ? 183 SER L N   1 
ATOM   8564  C CA  . SER C 3 183 ? 105.142 157.890 157.531 1.00 218.76 ? 183 SER L CA  1 
ATOM   8565  C C   . SER C 3 183 ? 106.456 158.668 157.515 1.00 223.29 ? 183 SER L C   1 
ATOM   8566  O O   . SER C 3 183 ? 107.021 158.960 158.569 1.00 174.17 ? 183 SER L O   1 
ATOM   8567  C CB  . SER C 3 183 ? 103.980 158.783 157.807 1.00 218.66 ? 183 SER L CB  1 
ATOM   8568  O OG  . SER C 3 183 ? 103.771 159.639 156.698 1.00 254.17 ? 183 SER L OG  1 
ATOM   8569  N N   . THR C 3 184 ? 106.923 158.990 156.301 1.00 238.46 ? 184 THR L N   1 
ATOM   8570  C CA  . THR C 3 184 ? 108.242 159.560 156.085 1.00 247.52 ? 184 THR L CA  1 
ATOM   8571  C C   . THR C 3 184 ? 108.119 160.770 155.164 1.00 290.28 ? 184 THR L C   1 
ATOM   8572  O O   . THR C 3 184 ? 107.422 160.695 154.158 1.00 322.58 ? 184 THR L O   1 
ATOM   8573  C CB  . THR C 3 184 ? 109.198 158.528 155.472 1.00 283.79 ? 184 THR L CB  1 
ATOM   8574  O OG1 . THR C 3 184 ? 109.323 157.398 156.338 1.00 257.98 ? 184 THR L OG1 1 
ATOM   8575  C CG2 . THR C 3 184 ? 110.583 159.085 155.223 1.00 312.78 ? 184 THR L CG2 1 
ATOM   8576  N N   . LEU C 3 185 ? 108.811 161.861 155.523 1.00 257.40 ? 185 LEU L N   1 
ATOM   8577  C CA  . LEU C 3 185 ? 108.938 163.055 154.702 1.00 216.71 ? 185 LEU L CA  1 
ATOM   8578  C C   . LEU C 3 185 ? 110.422 163.340 154.490 1.00 219.37 ? 185 LEU L C   1 
ATOM   8579  O O   . LEU C 3 185 ? 111.124 163.486 155.480 1.00 217.23 ? 185 LEU L O   1 
ATOM   8580  C CB  . LEU C 3 185 ? 108.246 164.204 155.436 1.00 201.37 ? 185 LEU L CB  1 
ATOM   8581  C CG  . LEU C 3 185 ? 108.521 165.612 154.910 1.00 230.46 ? 185 LEU L CG  1 
ATOM   8582  C CD1 . LEU C 3 185 ? 108.063 165.743 153.441 1.00 275.51 ? 185 LEU L CD1 1 
ATOM   8583  C CD2 . LEU C 3 185 ? 107.901 166.638 155.845 1.00 182.04 ? 185 LEU L CD2 1 
ATOM   8584  N N   . THR C 3 186 ? 110.882 163.415 153.221 1.00 236.25 ? 186 THR L N   1 
ATOM   8585  C CA  . THR C 3 186 ? 112.288 163.662 152.906 1.00 275.45 ? 186 THR L CA  1 
ATOM   8586  C C   . THR C 3 186 ? 112.461 165.050 152.274 1.00 273.49 ? 186 THR L C   1 
ATOM   8587  O O   . THR C 3 186 ? 111.731 165.426 151.348 1.00 195.33 ? 186 THR L O   1 
ATOM   8588  C CB  . THR C 3 186 ? 112.889 162.549 152.037 1.00 298.29 ? 186 THR L CB  1 
ATOM   8589  O OG1 . THR C 3 186 ? 112.966 161.356 152.823 1.00 275.77 ? 186 THR L OG1 1 
ATOM   8590  C CG2 . THR C 3 186 ? 114.280 162.870 151.529 1.00 331.75 ? 186 THR L CG2 1 
ATOM   8591  N N   . LEU C 3 187 ? 113.467 165.777 152.803 1.00 294.09 ? 187 LEU L N   1 
ATOM   8592  C CA  . LEU C 3 187 ? 113.760 167.175 152.524 1.00 285.22 ? 187 LEU L CA  1 
ATOM   8593  C C   . LEU C 3 187 ? 115.239 167.309 152.143 1.00 297.32 ? 187 LEU L C   1 
ATOM   8594  O O   . LEU C 3 187 ? 116.070 166.487 152.540 1.00 303.83 ? 187 LEU L O   1 
ATOM   8595  C CB  . LEU C 3 187 ? 113.493 168.004 153.793 1.00 272.90 ? 187 LEU L CB  1 
ATOM   8596  C CG  . LEU C 3 187 ? 112.149 167.833 154.505 1.00 226.70 ? 187 LEU L CG  1 
ATOM   8597  C CD1 . LEU C 3 187 ? 112.100 168.639 155.807 1.00 230.45 ? 187 LEU L CD1 1 
ATOM   8598  C CD2 . LEU C 3 187 ? 111.004 168.233 153.590 1.00 191.94 ? 187 LEU L CD2 1 
ATOM   8599  N N   . THR C 3 188 ? 115.595 168.369 151.397 1.00 289.53 ? 188 THR L N   1 
ATOM   8600  C CA  . THR C 3 188 ? 116.991 168.800 151.338 1.00 277.94 ? 188 THR L CA  1 
ATOM   8601  C C   . THR C 3 188 ? 117.360 169.446 152.678 1.00 258.82 ? 188 THR L C   1 
ATOM   8602  O O   . THR C 3 188 ? 116.485 169.845 153.447 1.00 296.17 ? 188 THR L O   1 
ATOM   8603  C CB  . THR C 3 188 ? 117.293 169.747 150.161 1.00 361.39 ? 188 THR L CB  1 
ATOM   8604  O OG1 . THR C 3 188 ? 116.828 171.070 150.440 1.00 373.52 ? 188 THR L OG1 1 
ATOM   8605  C CG2 . THR C 3 188 ? 116.704 169.278 148.845 1.00 401.83 ? 188 THR L CG2 1 
ATOM   8606  N N   . LYS C 3 189 ? 118.662 169.564 152.968 1.00 274.65 ? 189 LYS L N   1 
ATOM   8607  C CA  . LYS C 3 189 ? 119.111 170.182 154.214 1.00 290.11 ? 189 LYS L CA  1 
ATOM   8608  C C   . LYS C 3 189 ? 118.629 171.635 154.281 1.00 295.60 ? 189 LYS L C   1 
ATOM   8609  O O   . LYS C 3 189 ? 118.145 172.059 155.326 1.00 270.06 ? 189 LYS L O   1 
ATOM   8610  C CB  . LYS C 3 189 ? 120.634 170.079 154.366 1.00 293.18 ? 189 LYS L CB  1 
ATOM   8611  C CG  . LYS C 3 189 ? 121.191 170.539 155.706 1.00 298.85 ? 189 LYS L CG  1 
ATOM   8612  C CD  . LYS C 3 189 ? 122.699 170.460 155.775 1.00 349.40 ? 189 LYS L CD  1 
ATOM   8613  C CE  . LYS C 3 189 ? 123.267 170.811 157.136 1.00 400.13 ? 189 LYS L CE  1 
ATOM   8614  N NZ  . LYS C 3 189 ? 123.307 172.275 157.372 1.00 421.87 ? 189 LYS L NZ  1 
ATOM   8615  N N   . ASP C 3 190 ? 118.743 172.367 153.162 1.00 310.53 ? 190 ASP L N   1 
ATOM   8616  C CA  . ASP C 3 190 ? 118.349 173.770 153.051 1.00 331.40 ? 190 ASP L CA  1 
ATOM   8617  C C   . ASP C 3 190 ? 116.822 173.936 153.138 1.00 337.37 ? 190 ASP L C   1 
ATOM   8618  O O   . ASP C 3 190 ? 116.338 175.000 153.542 1.00 389.82 ? 190 ASP L O   1 
ATOM   8619  C CB  . ASP C 3 190 ? 118.868 174.400 151.748 1.00 337.19 ? 190 ASP L CB  1 
ATOM   8620  C CG  . ASP C 3 190 ? 120.340 174.197 151.394 1.00 379.79 ? 190 ASP L CG  1 
ATOM   8621  O OD1 . ASP C 3 190 ? 121.141 173.848 152.291 1.00 400.13 ? 190 ASP L OD1 1 
ATOM   8622  O OD2 . ASP C 3 190 ? 120.682 174.395 150.201 1.00 403.38 ? 190 ASP L OD2 1 
ATOM   8623  N N   . GLU C 3 191 ? 116.065 172.893 152.749 1.00 297.20 ? 191 GLU L N   1 
ATOM   8624  C CA  . GLU C 3 191 ? 114.614 172.822 152.897 1.00 311.30 ? 191 GLU L CA  1 
ATOM   8625  C C   . GLU C 3 191 ? 114.217 172.555 154.358 1.00 285.01 ? 191 GLU L C   1 
ATOM   8626  O O   . GLU C 3 191 ? 113.197 173.061 154.814 1.00 249.66 ? 191 GLU L O   1 
ATOM   8627  C CB  . GLU C 3 191 ? 114.113 171.750 151.924 1.00 321.39 ? 191 GLU L CB  1 
ATOM   8628  C CG  . GLU C 3 191 ? 112.613 171.566 151.843 1.00 357.89 ? 191 GLU L CG  1 
ATOM   8629  C CD  . GLU C 3 191 ? 112.198 170.535 150.800 1.00 401.16 ? 191 GLU L CD  1 
ATOM   8630  O OE1 . GLU C 3 191 ? 113.050 169.705 150.379 1.00 386.89 ? 191 GLU L OE1 1 
ATOM   8631  O OE2 . GLU C 3 191 ? 111.017 170.563 150.402 1.00 452.53 ? 191 GLU L OE2 1 
ATOM   8632  N N   . TYR C 3 192 ? 115.011 171.759 155.093 1.00 260.69 ? 192 TYR L N   1 
ATOM   8633  C CA  . TYR C 3 192 ? 114.844 171.576 156.534 1.00 254.57 ? 192 TYR L CA  1 
ATOM   8634  C C   . TYR C 3 192 ? 115.345 172.792 157.338 1.00 319.76 ? 192 TYR L C   1 
ATOM   8635  O O   . TYR C 3 192 ? 114.929 172.987 158.487 1.00 389.75 ? 192 TYR L O   1 
ATOM   8636  C CB  . TYR C 3 192 ? 115.532 170.268 156.953 1.00 261.77 ? 192 TYR L CB  1 
ATOM   8637  C CG  . TYR C 3 192 ? 115.584 170.042 158.459 1.00 279.82 ? 192 TYR L CG  1 
ATOM   8638  C CD1 . TYR C 3 192 ? 114.413 169.929 159.204 1.00 264.58 ? 192 TYR L CD1 1 
ATOM   8639  C CD2 . TYR C 3 192 ? 116.795 169.959 159.146 1.00 347.51 ? 192 TYR L CD2 1 
ATOM   8640  C CE1 . TYR C 3 192 ? 114.442 169.735 160.580 1.00 288.30 ? 192 TYR L CE1 1 
ATOM   8641  C CE2 . TYR C 3 192 ? 116.835 169.768 160.524 1.00 371.39 ? 192 TYR L CE2 1 
ATOM   8642  C CZ  . TYR C 3 192 ? 115.656 169.655 161.251 1.00 315.98 ? 192 TYR L CZ  1 
ATOM   8643  O OH  . TYR C 3 192 ? 115.731 169.458 162.609 1.00 206.37 ? 192 TYR L OH  1 
ATOM   8644  N N   . GLU C 3 193 ? 116.235 173.616 156.760 1.00 338.34 ? 193 GLU L N   1 
ATOM   8645  C CA  . GLU C 3 193 ? 116.812 174.772 157.442 1.00 350.52 ? 193 GLU L CA  1 
ATOM   8646  C C   . GLU C 3 193 ? 115.840 175.954 157.461 1.00 343.55 ? 193 GLU L C   1 
ATOM   8647  O O   . GLU C 3 193 ? 115.706 176.615 158.493 1.00 298.98 ? 193 GLU L O   1 
ATOM   8648  C CB  . GLU C 3 193 ? 118.132 175.162 156.769 1.00 408.04 ? 193 GLU L CB  1 
ATOM   8649  C CG  . GLU C 3 193 ? 119.061 175.967 157.666 1.00 461.36 ? 193 GLU L CG  1 
ATOM   8650  C CD  . GLU C 3 193 ? 119.718 175.219 158.817 1.00 470.75 ? 193 GLU L CD  1 
ATOM   8651  O OE1 . GLU C 3 193 ? 119.526 173.984 158.938 1.00 369.52 ? 193 GLU L OE1 1 
ATOM   8652  O OE2 . GLU C 3 193 ? 120.431 175.879 159.601 1.00 531.80 ? 193 GLU L OE2 1 
ATOM   8653  N N   . ARG C 3 194 ? 115.173 176.206 156.321 1.00 364.50 ? 194 ARG L N   1 
ATOM   8654  C CA  . ARG C 3 194 ? 114.372 177.406 156.099 1.00 369.58 ? 194 ARG L CA  1 
ATOM   8655  C C   . ARG C 3 194 ? 113.042 177.408 156.865 1.00 339.33 ? 194 ARG L C   1 
ATOM   8656  O O   . ARG C 3 194 ? 112.421 178.469 156.948 1.00 371.61 ? 194 ARG L O   1 
ATOM   8657  C CB  . ARG C 3 194 ? 114.110 177.604 154.597 1.00 381.47 ? 194 ARG L CB  1 
ATOM   8658  C CG  . ARG C 3 194 ? 113.279 176.521 153.917 1.00 386.27 ? 194 ARG L CG  1 
ATOM   8659  C CD  . ARG C 3 194 ? 113.229 176.695 152.412 1.00 396.16 ? 194 ARG L CD  1 
ATOM   8660  N NE  . ARG C 3 194 ? 114.541 176.541 151.791 1.00 435.33 ? 194 ARG L NE  1 
ATOM   8661  C CZ  . ARG C 3 194 ? 114.849 176.910 150.548 1.00 461.66 ? 194 ARG L CZ  1 
ATOM   8662  N NH1 . ARG C 3 194 ? 116.090 176.779 150.111 1.00 480.92 ? 194 ARG L NH1 1 
ATOM   8663  N NH2 . ARG C 3 194 ? 113.926 177.415 149.744 1.00 446.81 ? 194 ARG L NH2 1 
ATOM   8664  N N   . HIS C 3 195 ? 112.606 176.253 157.407 1.00 276.22 ? 195 HIS L N   1 
ATOM   8665  C CA  . HIS C 3 195 ? 111.354 176.131 158.148 1.00 286.52 ? 195 HIS L CA  1 
ATOM   8666  C C   . HIS C 3 195 ? 111.616 175.608 159.572 1.00 282.57 ? 195 HIS L C   1 
ATOM   8667  O O   . HIS C 3 195 ? 112.549 174.839 159.801 1.00 245.84 ? 195 HIS L O   1 
ATOM   8668  C CB  . HIS C 3 195 ? 110.378 175.275 157.320 1.00 316.69 ? 195 HIS L CB  1 
ATOM   8669  C CG  . HIS C 3 195 ? 109.930 175.880 156.018 1.00 343.23 ? 195 HIS L CG  1 
ATOM   8670  N ND1 . HIS C 3 195 ? 109.622 175.158 154.882 1.00 342.23 ? 195 HIS L ND1 1 
ATOM   8671  C CD2 . HIS C 3 195 ? 109.722 177.162 155.694 1.00 398.38 ? 195 HIS L CD2 1 
ATOM   8672  C CE1 . HIS C 3 195 ? 109.253 175.980 153.911 1.00 330.77 ? 195 HIS L CE1 1 
ATOM   8673  N NE2 . HIS C 3 195 ? 109.305 177.205 154.382 1.00 376.26 ? 195 HIS L NE2 1 
ATOM   8674  N N   . ASN C 3 196 ? 110.771 176.025 160.530 1.00 295.21 ? 196 ASN L N   1 
ATOM   8675  C CA  . ASN C 3 196 ? 111.043 175.919 161.963 1.00 310.97 ? 196 ASN L CA  1 
ATOM   8676  C C   . ASN C 3 196 ? 110.224 174.829 162.677 1.00 314.74 ? 196 ASN L C   1 
ATOM   8677  O O   . ASN C 3 196 ? 110.790 174.106 163.505 1.00 258.61 ? 196 ASN L O   1 
ATOM   8678  C CB  . ASN C 3 196 ? 110.799 177.280 162.622 1.00 369.14 ? 196 ASN L CB  1 
ATOM   8679  C CG  . ASN C 3 196 ? 111.022 177.280 164.120 1.00 396.16 ? 196 ASN L CG  1 
ATOM   8680  O OD1 . ASN C 3 196 ? 110.062 177.171 164.878 1.00 391.88 ? 196 ASN L OD1 1 
ATOM   8681  N ND2 . ASN C 3 196 ? 112.269 177.394 164.556 1.00 406.20 ? 196 ASN L ND2 1 
ATOM   8682  N N   . SER C 3 197 ? 108.907 174.726 162.379 1.00 329.79 ? 197 SER L N   1 
ATOM   8683  C CA  . SER C 3 197 ? 107.952 173.899 163.119 1.00 306.98 ? 197 SER L CA  1 
ATOM   8684  C C   . SER C 3 197 ? 107.341 172.805 162.232 1.00 317.43 ? 197 SER L C   1 
ATOM   8685  O O   . SER C 3 197 ? 106.688 173.111 161.230 1.00 237.88 ? 197 SER L O   1 
ATOM   8686  C CB  . SER C 3 197 ? 106.867 174.756 163.718 1.00 277.86 ? 197 SER L CB  1 
ATOM   8687  O OG  . SER C 3 197 ? 106.036 173.992 164.584 1.00 274.72 ? 197 SER L OG  1 
ATOM   8688  N N   . TYR C 3 198 ? 107.549 171.533 162.622 1.00 316.30 ? 198 TYR L N   1 
ATOM   8689  C CA  . TYR C 3 198 ? 107.141 170.367 161.849 1.00 279.34 ? 198 TYR L CA  1 
ATOM   8690  C C   . TYR C 3 198 ? 106.078 169.585 162.612 1.00 250.95 ? 198 TYR L C   1 
ATOM   8691  O O   . TYR C 3 198 ? 106.253 169.333 163.802 1.00 161.25 ? 198 TYR L O   1 
ATOM   8692  C CB  . TYR C 3 198 ? 108.370 169.505 161.571 1.00 265.63 ? 198 TYR L CB  1 
ATOM   8693  C CG  . TYR C 3 198 ? 109.374 170.229 160.694 1.00 299.85 ? 198 TYR L CG  1 
ATOM   8694  C CD1 . TYR C 3 198 ? 109.305 170.174 159.299 1.00 266.44 ? 198 TYR L CD1 1 
ATOM   8695  C CD2 . TYR C 3 198 ? 110.382 170.989 161.279 1.00 316.05 ? 198 TYR L CD2 1 
ATOM   8696  C CE1 . TYR C 3 198 ? 110.233 170.842 158.513 1.00 254.85 ? 198 TYR L CE1 1 
ATOM   8697  C CE2 . TYR C 3 198 ? 111.308 171.668 160.504 1.00 354.33 ? 198 TYR L CE2 1 
ATOM   8698  C CZ  . TYR C 3 198 ? 111.230 171.594 159.119 1.00 354.99 ? 198 TYR L CZ  1 
ATOM   8699  O OH  . TYR C 3 198 ? 112.145 172.266 158.366 1.00 418.94 ? 198 TYR L OH  1 
ATOM   8700  N N   . THR C 3 199 ? 104.995 169.209 161.905 1.00 299.18 ? 199 THR L N   1 
ATOM   8701  C CA  . THR C 3 199 ? 103.818 168.578 162.485 1.00 313.26 ? 199 THR L CA  1 
ATOM   8702  C C   . THR C 3 199 ? 103.427 167.337 161.675 1.00 280.41 ? 199 THR L C   1 
ATOM   8703  O O   . THR C 3 199 ? 103.365 167.386 160.450 1.00 247.70 ? 199 THR L O   1 
ATOM   8704  C CB  . THR C 3 199 ? 102.649 169.571 162.548 1.00 349.43 ? 199 THR L CB  1 
ATOM   8705  O OG1 . THR C 3 199 ? 103.003 170.663 163.399 1.00 355.15 ? 199 THR L OG1 1 
ATOM   8706  C CG2 . THR C 3 199 ? 101.364 168.955 163.058 1.00 356.40 ? 199 THR L CG2 1 
ATOM   8707  N N   . CYS C 3 200 ? 103.161 166.229 162.381 1.00 261.08 ? 200 CYS L N   1 
ATOM   8708  C CA  . CYS C 3 200 ? 102.499 165.048 161.847 1.00 262.14 ? 200 CYS L CA  1 
ATOM   8709  C C   . CYS C 3 200 ? 101.152 164.908 162.556 1.00 274.02 ? 200 CYS L C   1 
ATOM   8710  O O   . CYS C 3 200 ? 101.114 164.876 163.783 1.00 239.62 ? 200 CYS L O   1 
ATOM   8711  C CB  . CYS C 3 200 ? 103.375 163.825 162.091 1.00 269.71 ? 200 CYS L CB  1 
ATOM   8712  S SG  . CYS C 3 200 ? 102.643 162.232 161.642 1.00 310.24 ? 200 CYS L SG  1 
ATOM   8713  N N   . GLU C 3 201 ? 100.046 164.834 161.797 1.00 265.82 ? 201 GLU L N   1 
ATOM   8714  C CA  . GLU C 3 201 ? 98.725  164.677 162.396 1.00 253.65 ? 201 GLU L CA  1 
ATOM   8715  C C   . GLU C 3 201 ? 97.956  163.580 161.648 1.00 240.71 ? 201 GLU L C   1 
ATOM   8716  O O   . GLU C 3 201 ? 97.941  163.531 160.416 1.00 206.79 ? 201 GLU L O   1 
ATOM   8717  C CB  . GLU C 3 201 ? 98.013  166.040 162.494 1.00 319.15 ? 201 GLU L CB  1 
ATOM   8718  C CG  . GLU C 3 201 ? 97.667  166.734 161.178 1.00 369.87 ? 201 GLU L CG  1 
ATOM   8719  C CD  . GLU C 3 201 ? 97.206  168.185 161.283 1.00 381.16 ? 201 GLU L CD  1 
ATOM   8720  O OE1 . GLU C 3 201 ? 97.247  168.760 162.386 1.00 402.56 ? 201 GLU L OE1 1 
ATOM   8721  O OE2 . GLU C 3 201 ? 96.799  168.753 160.248 1.00 359.28 ? 201 GLU L OE2 1 
ATOM   8722  N N   . ALA C 3 202 ? 97.313  162.699 162.432 1.00 252.08 ? 202 ALA L N   1 
ATOM   8723  C CA  . ALA C 3 202 ? 96.755  161.445 161.949 1.00 243.71 ? 202 ALA L CA  1 
ATOM   8724  C C   . ALA C 3 202 ? 95.251  161.405 162.226 1.00 246.87 ? 202 ALA L C   1 
ATOM   8725  O O   . ALA C 3 202 ? 94.832  161.643 163.363 1.00 176.18 ? 202 ALA L O   1 
ATOM   8726  C CB  . ALA C 3 202 ? 97.472  160.301 162.621 1.00 229.51 ? 202 ALA L CB  1 
ATOM   8727  N N   . THR C 3 203 ? 94.455  161.109 161.180 1.00 275.00 ? 203 THR L N   1 
ATOM   8728  C CA  . THR C 3 203 ? 93.013  160.936 161.307 1.00 307.04 ? 203 THR L CA  1 
ATOM   8729  C C   . THR C 3 203 ? 92.683  159.451 161.198 1.00 282.05 ? 203 THR L C   1 
ATOM   8730  O O   . THR C 3 203 ? 93.021  158.809 160.198 1.00 234.28 ? 203 THR L O   1 
ATOM   8731  C CB  . THR C 3 203 ? 92.223  161.722 160.253 1.00 363.96 ? 203 THR L CB  1 
ATOM   8732  O OG1 . THR C 3 203 ? 92.690  163.072 160.212 1.00 395.62 ? 203 THR L OG1 1 
ATOM   8733  C CG2 . THR C 3 203 ? 90.733  161.725 160.522 1.00 395.88 ? 203 THR L CG2 1 
ATOM   8734  N N   . HIS C 3 204 ? 92.021  158.932 162.242 1.00 273.98 ? 204 HIS L N   1 
ATOM   8735  C CA  . HIS C 3 204 ? 91.633  157.535 162.324 1.00 282.12 ? 204 HIS L CA  1 
ATOM   8736  C C   . HIS C 3 204 ? 90.194  157.448 162.815 1.00 284.53 ? 204 HIS L C   1 
ATOM   8737  O O   . HIS C 3 204 ? 89.794  158.255 163.646 1.00 304.01 ? 204 HIS L O   1 
ATOM   8738  C CB  . HIS C 3 204 ? 92.562  156.781 163.275 1.00 290.58 ? 204 HIS L CB  1 
ATOM   8739  C CG  . HIS C 3 204 ? 92.282  155.321 163.224 1.00 308.24 ? 204 HIS L CG  1 
ATOM   8740  N ND1 . HIS C 3 204 ? 91.400  154.728 164.093 1.00 340.73 ? 204 HIS L ND1 1 
ATOM   8741  C CD2 . HIS C 3 204 ? 92.716  154.344 162.414 1.00 248.58 ? 204 HIS L CD2 1 
ATOM   8742  C CE1 . HIS C 3 204 ? 91.337  153.438 163.809 1.00 286.07 ? 204 HIS L CE1 1 
ATOM   8743  N NE2 . HIS C 3 204 ? 92.133  153.176 162.793 1.00 202.54 ? 204 HIS L NE2 1 
ATOM   8744  N N   . LYS C 3 205 ? 89.432  156.455 162.330 1.00 269.58 ? 205 LYS L N   1 
ATOM   8745  C CA  . LYS C 3 205 ? 87.983  156.401 162.525 1.00 275.95 ? 205 LYS L CA  1 
ATOM   8746  C C   . LYS C 3 205 ? 87.528  156.335 163.998 1.00 237.00 ? 205 LYS L C   1 
ATOM   8747  O O   . LYS C 3 205 ? 86.337  156.479 164.256 1.00 272.14 ? 205 LYS L O   1 
ATOM   8748  C CB  . LYS C 3 205 ? 87.393  155.212 161.752 1.00 299.26 ? 205 LYS L CB  1 
ATOM   8749  C CG  . LYS C 3 205 ? 87.800  153.818 162.230 1.00 351.94 ? 205 LYS L CG  1 
ATOM   8750  C CD  . LYS C 3 205 ? 86.796  152.721 161.923 1.00 349.83 ? 205 LYS L CD  1 
ATOM   8751  C CE  . LYS C 3 205 ? 85.470  152.903 162.631 1.00 344.57 ? 205 LYS L CE  1 
ATOM   8752  N NZ  . LYS C 3 205 ? 84.773  151.609 162.809 1.00 372.92 ? 205 LYS L NZ  1 
ATOM   8753  N N   . THR C 3 206 ? 88.440  156.115 164.957 1.00 238.88 ? 206 THR L N   1 
ATOM   8754  C CA  . THR C 3 206 ? 88.137  156.112 166.384 1.00 273.64 ? 206 THR L CA  1 
ATOM   8755  C C   . THR C 3 206 ? 88.003  157.514 166.998 1.00 308.00 ? 206 THR L C   1 
ATOM   8756  O O   . THR C 3 206 ? 87.571  157.605 168.147 1.00 315.06 ? 206 THR L O   1 
ATOM   8757  C CB  . THR C 3 206 ? 89.217  155.332 167.154 1.00 336.16 ? 206 THR L CB  1 
ATOM   8758  O OG1 . THR C 3 206 ? 90.506  155.816 166.771 1.00 379.00 ? 206 THR L OG1 1 
ATOM   8759  C CG2 . THR C 3 206 ? 89.175  153.838 166.913 1.00 336.96 ? 206 THR L CG2 1 
ATOM   8760  N N   . SER C 3 207 ? 88.366  158.596 166.278 1.00 351.72 ? 207 SER L N   1 
ATOM   8761  C CA  . SER C 3 207 ? 88.294  159.956 166.806 1.00 394.66 ? 207 SER L CA  1 
ATOM   8762  C C   . SER C 3 207 ? 87.821  160.935 165.729 1.00 399.50 ? 207 SER L C   1 
ATOM   8763  O O   . SER C 3 207 ? 88.220  160.831 164.569 1.00 385.49 ? 207 SER L O   1 
ATOM   8764  C CB  . SER C 3 207 ? 89.630  160.382 167.376 1.00 414.98 ? 207 SER L CB  1 
ATOM   8765  O OG  . SER C 3 207 ? 89.589  161.713 167.881 1.00 379.81 ? 207 SER L OG  1 
ATOM   8766  N N   . THR C 3 208 ? 86.971  161.892 166.134 1.00 408.12 ? 208 THR L N   1 
ATOM   8767  C CA  . THR C 3 208 ? 86.491  162.950 165.256 1.00 433.66 ? 208 THR L CA  1 
ATOM   8768  C C   . THR C 3 208 ? 87.638  163.904 164.925 1.00 371.73 ? 208 THR L C   1 
ATOM   8769  O O   . THR C 3 208 ? 87.862  164.201 163.751 1.00 300.23 ? 208 THR L O   1 
ATOM   8770  C CB  . THR C 3 208 ? 85.311  163.704 165.887 1.00 529.27 ? 208 THR L CB  1 
ATOM   8771  O OG1 . THR C 3 208 ? 84.322  162.753 166.286 1.00 558.45 ? 208 THR L OG1 1 
ATOM   8772  C CG2 . THR C 3 208 ? 84.679  164.717 164.956 1.00 565.79 ? 208 THR L CG2 1 
ATOM   8773  N N   . SER C 3 209 ? 88.339  164.369 165.975 1.00 391.20 ? 209 SER L N   1 
ATOM   8774  C CA  . SER C 3 209 ? 89.509  165.230 165.854 1.00 417.82 ? 209 SER L CA  1 
ATOM   8775  C C   . SER C 3 209 ? 90.756  164.411 165.499 1.00 405.88 ? 209 SER L C   1 
ATOM   8776  O O   . SER C 3 209 ? 90.897  163.280 165.976 1.00 449.56 ? 209 SER L O   1 
ATOM   8777  C CB  . SER C 3 209 ? 89.735  166.020 167.121 1.00 424.92 ? 209 SER L CB  1 
ATOM   8778  O OG  . SER C 3 209 ? 89.806  165.164 168.255 1.00 399.17 ? 209 SER L OG  1 
ATOM   8779  N N   . PRO C 3 210 ? 91.696  164.935 164.663 1.00 336.15 ? 210 PRO L N   1 
ATOM   8780  C CA  . PRO C 3 210 ? 93.003  164.298 164.475 1.00 305.48 ? 210 PRO L CA  1 
ATOM   8781  C C   . PRO C 3 210 ? 93.857  164.285 165.744 1.00 291.82 ? 210 PRO L C   1 
ATOM   8782  O O   . PRO C 3 210 ? 93.728  165.173 166.588 1.00 236.66 ? 210 PRO L O   1 
ATOM   8783  C CB  . PRO C 3 210 ? 93.708  165.152 163.405 1.00 306.15 ? 210 PRO L CB  1 
ATOM   8784  C CG  . PRO C 3 210 ? 92.597  165.937 162.743 1.00 301.37 ? 210 PRO L CG  1 
ATOM   8785  C CD  . PRO C 3 210 ? 91.570  166.147 163.833 1.00 324.71 ? 210 PRO L CD  1 
ATOM   8786  N N   . ILE C 3 211 ? 94.718  163.262 165.852 1.00 316.06 ? 211 ILE L N   1 
ATOM   8787  C CA  . ILE C 3 211 ? 95.781  163.205 166.846 1.00 286.61 ? 211 ILE L CA  1 
ATOM   8788  C C   . ILE C 3 211 ? 96.965  163.963 166.252 1.00 256.43 ? 211 ILE L C   1 
ATOM   8789  O O   . ILE C 3 211 ? 97.182  163.889 165.046 1.00 210.26 ? 211 ILE L O   1 
ATOM   8790  C CB  . ILE C 3 211 ? 96.107  161.735 167.216 1.00 275.31 ? 211 ILE L CB  1 
ATOM   8791  C CG1 . ILE C 3 211 ? 94.902  161.045 167.869 1.00 339.90 ? 211 ILE L CG1 1 
ATOM   8792  C CG2 . ILE C 3 211 ? 97.357  161.612 168.087 1.00 208.30 ? 211 ILE L CG2 1 
ATOM   8793  C CD1 . ILE C 3 211 ? 94.879  159.532 167.718 1.00 355.72 ? 211 ILE L CD1 1 
ATOM   8794  N N   . VAL C 3 212 ? 97.715  164.679 167.106 1.00 275.83 ? 212 VAL L N   1 
ATOM   8795  C CA  . VAL C 3 212 ? 98.778  165.585 166.682 1.00 260.05 ? 212 VAL L CA  1 
ATOM   8796  C C   . VAL C 3 212 ? 100.043 165.306 167.494 1.00 250.24 ? 212 VAL L C   1 
ATOM   8797  O O   . VAL C 3 212 ? 99.986  165.103 168.709 1.00 203.22 ? 212 VAL L O   1 
ATOM   8798  C CB  . VAL C 3 212 ? 98.358  167.058 166.849 1.00 300.77 ? 212 VAL L CB  1 
ATOM   8799  C CG1 . VAL C 3 212 ? 99.509  168.021 166.565 1.00 302.92 ? 212 VAL L CG1 1 
ATOM   8800  C CG2 . VAL C 3 212 ? 97.135  167.393 166.006 1.00 320.75 ? 212 VAL L CG2 1 
ATOM   8801  N N   . LYS C 3 213 ? 101.185 165.309 166.791 1.00 257.08 ? 213 LYS L N   1 
ATOM   8802  C CA  . LYS C 3 213 ? 102.503 165.464 167.391 1.00 273.82 ? 213 LYS L CA  1 
ATOM   8803  C C   . LYS C 3 213 ? 103.342 166.392 166.508 1.00 283.19 ? 213 LYS L C   1 
ATOM   8804  O O   . LYS C 3 213 ? 103.145 166.452 165.291 1.00 245.08 ? 213 LYS L O   1 
ATOM   8805  C CB  . LYS C 3 213 ? 103.201 164.108 167.558 1.00 250.22 ? 213 LYS L CB  1 
ATOM   8806  C CG  . LYS C 3 213 ? 102.595 163.139 168.570 1.00 258.11 ? 213 LYS L CG  1 
ATOM   8807  C CD  . LYS C 3 213 ? 102.755 163.553 170.022 1.00 298.96 ? 213 LYS L CD  1 
ATOM   8808  C CE  . LYS C 3 213 ? 102.260 162.500 170.993 1.00 335.08 ? 213 LYS L CE  1 
ATOM   8809  N NZ  . LYS C 3 213 ? 102.074 163.049 172.358 1.00 366.18 ? 213 LYS L NZ  1 
ATOM   8810  N N   . SER C 3 214 ? 104.284 167.115 167.133 1.00 271.10 ? 214 SER L N   1 
ATOM   8811  C CA  . SER C 3 214 ? 105.061 168.141 166.451 1.00 248.98 ? 214 SER L CA  1 
ATOM   8812  C C   . SER C 3 214 ? 106.366 168.429 167.198 1.00 284.46 ? 214 SER L C   1 
ATOM   8813  O O   . SER C 3 214 ? 106.515 168.029 168.359 1.00 229.89 ? 214 SER L O   1 
ATOM   8814  C CB  . SER C 3 214 ? 104.234 169.399 166.279 1.00 265.34 ? 214 SER L CB  1 
ATOM   8815  O OG  . SER C 3 214 ? 103.813 169.914 167.540 1.00 307.17 ? 214 SER L OG  1 
ATOM   8816  N N   . PHE C 3 215 ? 107.300 169.118 166.508 1.00 291.44 ? 215 PHE L N   1 
ATOM   8817  C CA  . PHE C 3 215 ? 108.524 169.632 167.116 1.00 312.61 ? 215 PHE L CA  1 
ATOM   8818  C C   . PHE C 3 215 ? 108.984 170.916 166.414 1.00 331.93 ? 215 PHE L C   1 
ATOM   8819  O O   . PHE C 3 215 ? 108.663 171.145 165.246 1.00 274.26 ? 215 PHE L O   1 
ATOM   8820  C CB  . PHE C 3 215 ? 109.632 168.572 167.106 1.00 284.06 ? 215 PHE L CB  1 
ATOM   8821  C CG  . PHE C 3 215 ? 110.209 168.262 165.746 1.00 304.47 ? 215 PHE L CG  1 
ATOM   8822  C CD1 . PHE C 3 215 ? 109.609 167.333 164.908 1.00 327.94 ? 215 PHE L CD1 1 
ATOM   8823  C CD2 . PHE C 3 215 ? 111.357 168.904 165.297 1.00 358.35 ? 215 PHE L CD2 1 
ATOM   8824  C CE1 . PHE C 3 215 ? 110.143 167.048 163.658 1.00 317.98 ? 215 PHE L CE1 1 
ATOM   8825  C CE2 . PHE C 3 215 ? 111.887 168.618 164.045 1.00 344.89 ? 215 PHE L CE2 1 
ATOM   8826  C CZ  . PHE C 3 215 ? 111.281 167.691 163.225 1.00 317.52 ? 215 PHE L CZ  1 
ATOM   8827  N N   . ASN C 3 216 ? 109.745 171.738 167.157 1.00 377.34 ? 216 ASN L N   1 
ATOM   8828  C CA  . ASN C 3 216 ? 110.370 172.956 166.659 1.00 376.71 ? 216 ASN L CA  1 
ATOM   8829  C C   . ASN C 3 216 ? 111.886 172.782 166.742 1.00 343.30 ? 216 ASN L C   1 
ATOM   8830  O O   . ASN C 3 216 ? 112.396 172.473 167.820 1.00 299.46 ? 216 ASN L O   1 
ATOM   8831  C CB  . ASN C 3 216 ? 109.922 174.195 167.443 1.00 388.79 ? 216 ASN L CB  1 
ATOM   8832  C CG  . ASN C 3 216 ? 108.419 174.289 167.634 1.00 386.97 ? 216 ASN L CG  1 
ATOM   8833  O OD1 . ASN C 3 216 ? 107.657 173.990 166.717 1.00 356.89 ? 216 ASN L OD1 1 
ATOM   8834  N ND2 . ASN C 3 216 ? 107.978 174.694 168.817 1.00 390.57 ? 216 ASN L ND2 1 
ATOM   8835  N N   . ARG C 3 217 ? 112.597 172.988 165.620 1.00 332.29 ? 217 ARG L N   1 
ATOM   8836  C CA  . ARG C 3 217 ? 114.008 172.618 165.521 1.00 348.83 ? 217 ARG L CA  1 
ATOM   8837  C C   . ARG C 3 217 ? 114.849 173.582 166.383 1.00 284.28 ? 217 ARG L C   1 
ATOM   8838  O O   . ARG C 3 217 ? 116.068 173.678 166.121 1.00 285.67 ? 217 ARG L O   1 
ATOM   8839  C CB  . ARG C 3 217 ? 114.452 172.530 164.046 1.00 401.36 ? 217 ARG L CB  1 
ATOM   8840  C CG  . ARG C 3 217 ? 114.327 173.820 163.237 1.00 401.83 ? 217 ARG L CG  1 
ATOM   8841  C CD  . ARG C 3 217 ? 115.116 173.730 161.944 1.00 417.82 ? 217 ARG L CD  1 
ATOM   8842  N NE  . ARG C 3 217 ? 116.547 173.850 162.209 1.00 454.03 ? 217 ARG L NE  1 
ATOM   8843  C CZ  . ARG C 3 217 ? 117.536 173.479 161.390 1.00 457.08 ? 217 ARG L CZ  1 
ATOM   8844  N NH1 . ARG C 3 217 ? 117.299 172.964 160.191 1.00 454.92 ? 217 ARG L NH1 1 
ATOM   8845  N NH2 . ARG C 3 217 ? 118.792 173.628 161.789 1.00 438.64 ? 217 ARG L NH2 1 
ATOM   8846  N N   . GLU D 4 1   ? 115.301 116.341 163.842 1.00 309.59 ? 1   GLU H N   1 
ATOM   8847  C CA  . GLU D 4 1   ? 115.453 117.522 162.950 1.00 256.70 ? 1   GLU H CA  1 
ATOM   8848  C C   . GLU D 4 1   ? 115.529 117.072 161.491 1.00 238.07 ? 1   GLU H C   1 
ATOM   8849  O O   . GLU D 4 1   ? 116.216 116.111 161.180 1.00 247.42 ? 1   GLU H O   1 
ATOM   8850  C CB  . GLU D 4 1   ? 116.722 118.292 163.301 1.00 239.12 ? 1   GLU H CB  1 
ATOM   8851  C CG  . GLU D 4 1   ? 117.072 119.378 162.296 1.00 296.59 ? 1   GLU H CG  1 
ATOM   8852  C CD  . GLU D 4 1   ? 118.375 120.111 162.565 1.00 381.88 ? 1   GLU H CD  1 
ATOM   8853  O OE1 . GLU D 4 1   ? 119.390 119.432 162.825 1.00 410.28 ? 1   GLU H OE1 1 
ATOM   8854  O OE2 . GLU D 4 1   ? 118.373 121.364 162.496 1.00 439.17 ? 1   GLU H OE2 1 
ATOM   8855  N N   . VAL D 4 2   ? 114.806 117.786 160.617 1.00 190.08 ? 2   VAL H N   1 
ATOM   8856  C CA  . VAL D 4 2   ? 115.066 117.870 159.186 1.00 143.71 ? 2   VAL H CA  1 
ATOM   8857  C C   . VAL D 4 2   ? 115.203 119.348 158.887 1.00 123.54 ? 2   VAL H C   1 
ATOM   8858  O O   . VAL D 4 2   ? 114.326 120.120 159.289 1.00 193.51 ? 2   VAL H O   1 
ATOM   8859  C CB  . VAL D 4 2   ? 113.944 117.217 158.326 1.00 139.70 ? 2   VAL H CB  1 
ATOM   8860  C CG1 . VAL D 4 2   ? 114.046 117.578 156.849 1.00 100.41 ? 2   VAL H CG1 1 
ATOM   8861  C CG2 . VAL D 4 2   ? 113.967 115.705 158.487 1.00 185.46 ? 2   VAL H CG2 1 
ATOM   8862  N N   . GLN D 4 3   ? 116.268 119.744 158.197 1.00 98.46  ? 3   GLN H N   1 
ATOM   8863  C CA  . GLN D 4 3   ? 116.440 121.163 157.927 1.00 135.78 ? 3   GLN H CA  1 
ATOM   8864  C C   . GLN D 4 3   ? 117.136 121.371 156.588 1.00 122.36 ? 3   GLN H C   1 
ATOM   8865  O O   . GLN D 4 3   ? 118.283 120.943 156.409 1.00 90.05  ? 3   GLN H O   1 
ATOM   8866  C CB  . GLN D 4 3   ? 117.255 121.817 159.041 1.00 160.50 ? 3   GLN H CB  1 
ATOM   8867  C CG  . GLN D 4 3   ? 117.449 123.326 158.933 1.00 209.37 ? 3   GLN H CG  1 
ATOM   8868  C CD  . GLN D 4 3   ? 118.772 123.787 159.511 1.00 249.03 ? 3   GLN H CD  1 
ATOM   8869  O OE1 . GLN D 4 3   ? 119.615 124.370 158.825 1.00 250.05 ? 3   GLN H OE1 1 
ATOM   8870  N NE2 . GLN D 4 3   ? 118.961 123.517 160.792 1.00 263.77 ? 3   GLN H NE2 1 
ATOM   8871  N N   . LEU D 4 4   ? 116.411 122.061 155.697 1.00 98.81  ? 4   LEU H N   1 
ATOM   8872  C CA  . LEU D 4 4   ? 116.999 122.629 154.505 1.00 91.32  ? 4   LEU H CA  1 
ATOM   8873  C C   . LEU D 4 4   ? 117.351 124.079 154.830 1.00 107.79 ? 4   LEU H C   1 
ATOM   8874  O O   . LEU D 4 4   ? 116.553 124.727 155.519 1.00 102.59 ? 4   LEU H O   1 
ATOM   8875  C CB  . LEU D 4 4   ? 115.967 122.561 153.368 1.00 101.69 ? 4   LEU H CB  1 
ATOM   8876  C CG  . LEU D 4 4   ? 115.245 121.238 153.121 1.00 106.79 ? 4   LEU H CG  1 
ATOM   8877  C CD1 . LEU D 4 4   ? 114.430 121.280 151.813 1.00 123.34 ? 4   LEU H CD1 1 
ATOM   8878  C CD2 . LEU D 4 4   ? 116.232 120.095 153.076 1.00 109.40 ? 4   LEU H CD2 1 
ATOM   8879  N N   . GLN D 4 5   ? 118.498 124.589 154.337 1.00 121.26 ? 5   GLN H N   1 
ATOM   8880  C CA  . GLN D 4 5   ? 118.705 126.035 154.318 1.00 147.20 ? 5   GLN H CA  1 
ATOM   8881  C C   . GLN D 4 5   ? 119.297 126.550 153.004 1.00 117.96 ? 5   GLN H C   1 
ATOM   8882  O O   . GLN D 4 5   ? 119.929 125.793 152.260 1.00 138.04 ? 5   GLN H O   1 
ATOM   8883  C CB  . GLN D 4 5   ? 119.584 126.403 155.496 1.00 174.50 ? 5   GLN H CB  1 
ATOM   8884  C CG  . GLN D 4 5   ? 120.983 125.827 155.404 1.00 195.48 ? 5   GLN H CG  1 
ATOM   8885  C CD  . GLN D 4 5   ? 121.793 126.618 156.394 1.00 240.22 ? 5   GLN H CD  1 
ATOM   8886  O OE1 . GLN D 4 5   ? 122.576 127.499 156.024 1.00 213.51 ? 5   GLN H OE1 1 
ATOM   8887  N NE2 . GLN D 4 5   ? 121.569 126.310 157.666 1.00 301.50 ? 5   GLN H NE2 1 
ATOM   8888  N N   . GLN D 4 6   ? 119.063 127.851 152.761 1.00 113.89 ? 6   GLN H N   1 
ATOM   8889  C CA  . GLN D 4 6   ? 119.425 128.515 151.521 1.00 125.00 ? 6   GLN H CA  1 
ATOM   8890  C C   . GLN D 4 6   ? 120.018 129.887 151.796 1.00 119.20 ? 6   GLN H C   1 
ATOM   8891  O O   . GLN D 4 6   ? 119.659 130.528 152.773 1.00 146.63 ? 6   GLN H O   1 
ATOM   8892  C CB  . GLN D 4 6   ? 118.231 128.777 150.596 1.00 110.57 ? 6   GLN H CB  1 
ATOM   8893  C CG  . GLN D 4 6   ? 117.268 127.608 150.419 1.00 112.93 ? 6   GLN H CG  1 
ATOM   8894  C CD  . GLN D 4 6   ? 116.229 127.954 149.375 1.00 107.58 ? 6   GLN H CD  1 
ATOM   8895  O OE1 . GLN D 4 6   ? 116.389 127.604 148.211 1.00 210.83 ? 6   GLN H OE1 1 
ATOM   8896  N NE2 . GLN D 4 6   ? 115.163 128.637 149.743 1.00 77.85  ? 6   GLN H NE2 1 
ATOM   8897  N N   . SER D 4 7   ? 120.911 130.298 150.894 1.00 129.39 ? 7   SER H N   1 
ATOM   8898  C CA  . SER D 4 7   ? 121.338 131.673 150.775 1.00 155.18 ? 7   SER H CA  1 
ATOM   8899  C C   . SER D 4 7   ? 120.124 132.599 150.736 1.00 150.73 ? 7   SER H C   1 
ATOM   8900  O O   . SER D 4 7   ? 119.071 132.192 150.235 1.00 102.89 ? 7   SER H O   1 
ATOM   8901  C CB  . SER D 4 7   ? 122.226 131.853 149.550 1.00 176.01 ? 7   SER H CB  1 
ATOM   8902  O OG  . SER D 4 7   ? 121.555 131.597 148.315 1.00 102.65 ? 7   SER H OG  1 
ATOM   8903  N N   . GLY D 4 8   ? 120.307 133.831 151.257 1.00 149.41 ? 8   GLY H N   1 
ATOM   8904  C CA  . GLY D 4 8   ? 119.194 134.706 151.586 1.00 162.34 ? 8   GLY H CA  1 
ATOM   8905  C C   . GLY D 4 8   ? 118.672 135.521 150.397 1.00 156.38 ? 8   GLY H C   1 
ATOM   8906  O O   . GLY D 4 8   ? 117.466 135.811 150.304 1.00 115.23 ? 8   GLY H O   1 
ATOM   8907  N N   . ALA D 4 9   ? 119.589 135.900 149.490 1.00 112.51 ? 9   ALA H N   1 
ATOM   8908  C CA  . ALA D 4 9   ? 119.326 136.951 148.519 1.00 98.30  ? 9   ALA H CA  1 
ATOM   8909  C C   . ALA D 4 9   ? 120.324 136.804 147.396 1.00 123.04 ? 9   ALA H C   1 
ATOM   8910  O O   . ALA D 4 9   ? 121.495 136.449 147.647 1.00 150.41 ? 9   ALA H O   1 
ATOM   8911  C CB  . ALA D 4 9   ? 119.512 138.308 149.159 1.00 193.39 ? 9   ALA H CB  1 
ATOM   8912  N N   . GLU D 4 10  ? 119.853 137.112 146.186 1.00 111.47 ? 10  GLU H N   1 
ATOM   8913  C CA  . GLU D 4 10  ? 120.732 137.172 145.034 1.00 157.72 ? 10  GLU H CA  1 
ATOM   8914  C C   . GLU D 4 10  ? 120.297 138.345 144.174 1.00 186.45 ? 10  GLU H C   1 
ATOM   8915  O O   . GLU D 4 10  ? 119.098 138.618 144.056 1.00 150.42 ? 10  GLU H O   1 
ATOM   8916  C CB  . GLU D 4 10  ? 120.698 135.884 144.201 1.00 182.35 ? 10  GLU H CB  1 
ATOM   8917  C CG  . GLU D 4 10  ? 120.982 134.597 144.979 1.00 248.11 ? 10  GLU H CG  1 
ATOM   8918  C CD  . GLU D 4 10  ? 122.361 134.440 145.615 1.00 233.92 ? 10  GLU H CD  1 
ATOM   8919  O OE1 . GLU D 4 10  ? 123.276 135.193 145.231 1.00 264.46 ? 10  GLU H OE1 1 
ATOM   8920  O OE2 . GLU D 4 10  ? 122.517 133.563 146.509 1.00 287.03 ? 10  GLU H OE2 1 
ATOM   8921  N N   . LEU D 4 11  ? 121.296 139.013 143.574 1.00 171.54 ? 11  LEU H N   1 
ATOM   8922  C CA  . LEU D 4 11  ? 121.050 140.012 142.555 1.00 175.86 ? 11  LEU H CA  1 
ATOM   8923  C C   . LEU D 4 11  ? 121.498 139.483 141.189 1.00 169.56 ? 11  LEU H C   1 
ATOM   8924  O O   . LEU D 4 11  ? 122.557 138.858 141.086 1.00 138.86 ? 11  LEU H O   1 
ATOM   8925  C CB  . LEU D 4 11  ? 121.800 141.274 142.984 1.00 184.65 ? 11  LEU H CB  1 
ATOM   8926  C CG  . LEU D 4 11  ? 121.646 142.479 142.055 1.00 187.31 ? 11  LEU H CG  1 
ATOM   8927  C CD1 . LEU D 4 11  ? 120.178 142.867 141.796 1.00 137.73 ? 11  LEU H CD1 1 
ATOM   8928  C CD2 . LEU D 4 11  ? 122.424 143.656 142.637 1.00 216.81 ? 11  LEU H CD2 1 
ATOM   8929  N N   . VAL D 4 12  ? 120.685 139.737 140.149 1.00 144.91 ? 12  VAL H N   1 
ATOM   8930  C CA  . VAL D 4 12  ? 120.980 139.279 138.803 1.00 158.23 ? 12  VAL H CA  1 
ATOM   8931  C C   . VAL D 4 12  ? 120.778 140.402 137.800 1.00 185.20 ? 12  VAL H C   1 
ATOM   8932  O O   . VAL D 4 12  ? 119.671 140.921 137.738 1.00 174.59 ? 12  VAL H O   1 
ATOM   8933  C CB  . VAL D 4 12  ? 120.058 138.116 138.428 1.00 183.31 ? 12  VAL H CB  1 
ATOM   8934  C CG1 . VAL D 4 12  ? 120.328 137.631 137.005 1.00 247.58 ? 12  VAL H CG1 1 
ATOM   8935  C CG2 . VAL D 4 12  ? 120.176 136.984 139.433 1.00 241.00 ? 12  VAL H CG2 1 
ATOM   8936  N N   . LYS D 4 13  ? 121.813 140.749 137.002 1.00 201.27 ? 13  LYS H N   1 
ATOM   8937  C CA  . LYS D 4 13  ? 121.642 141.691 135.895 1.00 211.93 ? 13  LYS H CA  1 
ATOM   8938  C C   . LYS D 4 13  ? 120.862 141.015 134.765 1.00 144.34 ? 13  LYS H C   1 
ATOM   8939  O O   . LYS D 4 13  ? 121.235 139.916 134.376 1.00 144.98 ? 13  LYS H O   1 
ATOM   8940  C CB  . LYS D 4 13  ? 122.988 142.231 135.409 1.00 252.25 ? 13  LYS H CB  1 
ATOM   8941  C CG  . LYS D 4 13  ? 123.668 143.165 136.403 1.00 313.28 ? 13  LYS H CG  1 
ATOM   8942  C CD  . LYS D 4 13  ? 124.710 144.066 135.783 1.00 372.69 ? 13  LYS H CD  1 
ATOM   8943  C CE  . LYS D 4 13  ? 125.844 143.306 135.128 1.00 452.37 ? 13  LYS H CE  1 
ATOM   8944  N NZ  . LYS D 4 13  ? 126.903 144.221 134.641 1.00 499.08 ? 13  LYS H NZ  1 
ATOM   8945  N N   . PRO D 4 14  ? 119.758 141.614 134.237 1.00 144.66 ? 14  PRO H N   1 
ATOM   8946  C CA  . PRO D 4 14  ? 118.853 140.933 133.293 1.00 175.42 ? 14  PRO H CA  1 
ATOM   8947  C C   . PRO D 4 14  ? 119.561 140.180 132.166 1.00 186.88 ? 14  PRO H C   1 
ATOM   8948  O O   . PRO D 4 14  ? 120.558 140.658 131.622 1.00 216.76 ? 14  PRO H O   1 
ATOM   8949  C CB  . PRO D 4 14  ? 117.956 142.051 132.716 1.00 160.56 ? 14  PRO H CB  1 
ATOM   8950  C CG  . PRO D 4 14  ? 117.921 143.087 133.838 1.00 164.46 ? 14  PRO H CG  1 
ATOM   8951  C CD  . PRO D 4 14  ? 119.273 142.976 134.535 1.00 151.28 ? 14  PRO H CD  1 
ATOM   8952  N N   . GLY D 4 15  ? 119.031 138.994 131.853 1.00 173.09 ? 15  GLY H N   1 
ATOM   8953  C CA  . GLY D 4 15  ? 119.633 138.092 130.885 1.00 225.17 ? 15  GLY H CA  1 
ATOM   8954  C C   . GLY D 4 15  ? 120.651 137.095 131.462 1.00 205.12 ? 15  GLY H C   1 
ATOM   8955  O O   . GLY D 4 15  ? 120.883 136.047 130.845 1.00 204.63 ? 15  GLY H O   1 
ATOM   8956  N N   . ALA D 4 16  ? 121.264 137.388 132.618 1.00 177.30 ? 16  ALA H N   1 
ATOM   8957  C CA  . ALA D 4 16  ? 122.324 136.539 133.151 1.00 223.21 ? 16  ALA H CA  1 
ATOM   8958  C C   . ALA D 4 16  ? 121.737 135.299 133.827 1.00 186.35 ? 16  ALA H C   1 
ATOM   8959  O O   . ALA D 4 16  ? 120.567 135.267 134.144 1.00 135.23 ? 16  ALA H O   1 
ATOM   8960  C CB  . ALA D 4 16  ? 123.197 137.340 134.101 1.00 259.79 ? 16  ALA H CB  1 
ATOM   8961  N N   . SER D 4 17  ? 122.567 134.276 134.047 1.00 209.36 ? 17  SER H N   1 
ATOM   8962  C CA  . SER D 4 17  ? 122.181 133.129 134.852 1.00 240.23 ? 17  SER H CA  1 
ATOM   8963  C C   . SER D 4 17  ? 122.410 133.413 136.337 1.00 197.94 ? 17  SER H C   1 
ATOM   8964  O O   . SER D 4 17  ? 123.119 134.364 136.681 1.00 164.22 ? 17  SER H O   1 
ATOM   8965  C CB  . SER D 4 17  ? 122.927 131.884 134.410 1.00 329.78 ? 17  SER H CB  1 
ATOM   8966  O OG  . SER D 4 17  ? 124.323 131.981 134.686 1.00 324.38 ? 17  SER H OG  1 
ATOM   8967  N N   . VAL D 4 18  ? 121.813 132.561 137.198 1.00 168.83 ? 18  VAL H N   1 
ATOM   8968  C CA  . VAL D 4 18  ? 122.124 132.527 138.622 1.00 149.21 ? 18  VAL H CA  1 
ATOM   8969  C C   . VAL D 4 18  ? 122.087 131.107 139.187 1.00 108.49 ? 18  VAL H C   1 
ATOM   8970  O O   . VAL D 4 18  ? 121.308 130.289 138.686 1.00 155.12 ? 18  VAL H O   1 
ATOM   8971  C CB  . VAL D 4 18  ? 121.139 133.435 139.375 1.00 152.51 ? 18  VAL H CB  1 
ATOM   8972  C CG1 . VAL D 4 18  ? 119.690 132.973 139.223 1.00 104.46 ? 18  VAL H CG1 1 
ATOM   8973  C CG2 . VAL D 4 18  ? 121.551 133.591 140.847 1.00 165.28 ? 18  VAL H CG2 1 
ATOM   8974  N N   . ASN D 4 19  ? 122.912 130.853 140.219 1.00 127.66 ? 19  ASN H N   1 
ATOM   8975  C CA  . ASN D 4 19  ? 122.860 129.626 141.022 1.00 175.24 ? 19  ASN H CA  1 
ATOM   8976  C C   . ASN D 4 19  ? 122.285 129.935 142.407 1.00 146.69 ? 19  ASN H C   1 
ATOM   8977  O O   . ASN D 4 19  ? 122.799 130.793 143.126 1.00 150.91 ? 19  ASN H O   1 
ATOM   8978  C CB  . ASN D 4 19  ? 124.216 128.922 141.197 1.00 185.09 ? 19  ASN H CB  1 
ATOM   8979  C CG  . ASN D 4 19  ? 124.676 128.189 139.951 1.00 237.26 ? 19  ASN H CG  1 
ATOM   8980  O OD1 . ASN D 4 19  ? 124.742 128.788 138.874 1.00 220.36 ? 19  ASN H OD1 1 
ATOM   8981  N ND2 . ASN D 4 19  ? 124.987 126.904 140.081 1.00 256.15 ? 19  ASN H ND2 1 
ATOM   8982  N N   . LEU D 4 20  ? 121.210 129.230 142.757 1.00 114.00 ? 20  LEU H N   1 
ATOM   8983  C CA  . LEU D 4 20  ? 120.609 129.255 144.074 1.00 99.49  ? 20  LEU H CA  1 
ATOM   8984  C C   . LEU D 4 20  ? 120.862 127.882 144.699 1.00 118.72 ? 20  LEU H C   1 
ATOM   8985  O O   . LEU D 4 20  ? 120.726 126.883 143.996 1.00 145.43 ? 20  LEU H O   1 
ATOM   8986  C CB  . LEU D 4 20  ? 119.097 129.477 143.930 1.00 88.64  ? 20  LEU H CB  1 
ATOM   8987  C CG  . LEU D 4 20  ? 118.628 130.414 142.841 1.00 99.13  ? 20  LEU H CG  1 
ATOM   8988  C CD1 . LEU D 4 20  ? 117.106 130.426 142.695 1.00 114.01 ? 20  LEU H CD1 1 
ATOM   8989  C CD2 . LEU D 4 20  ? 119.127 131.795 143.152 1.00 167.83 ? 20  LEU H CD2 1 
ATOM   8990  N N   . SER D 4 21  ? 121.164 127.809 146.001 1.00 93.23  ? 21  SER H N   1 
ATOM   8991  C CA  . SER D 4 21  ? 121.672 126.580 146.590 1.00 96.96  ? 21  SER H CA  1 
ATOM   8992  C C   . SER D 4 21  ? 121.002 126.230 147.903 1.00 82.34  ? 21  SER H C   1 
ATOM   8993  O O   . SER D 4 21  ? 120.612 127.107 148.641 1.00 124.39 ? 21  SER H O   1 
ATOM   8994  C CB  . SER D 4 21  ? 123.154 126.729 146.793 1.00 194.96 ? 21  SER H CB  1 
ATOM   8995  O OG  . SER D 4 21  ? 123.486 127.851 147.617 1.00 221.05 ? 21  SER H OG  1 
ATOM   8996  N N   . CYS D 4 22  ? 120.879 124.940 148.196 1.00 84.84  ? 22  CYS H N   1 
ATOM   8997  C CA  . CYS D 4 22  ? 120.039 124.415 149.263 1.00 90.73  ? 22  CYS H CA  1 
ATOM   8998  C C   . CYS D 4 22  ? 120.683 123.223 149.949 1.00 88.06  ? 22  CYS H C   1 
ATOM   8999  O O   . CYS D 4 22  ? 120.800 122.143 149.342 1.00 129.28 ? 22  CYS H O   1 
ATOM   9000  C CB  . CYS D 4 22  ? 118.723 123.904 148.700 1.00 103.05 ? 22  CYS H CB  1 
ATOM   9001  S SG  . CYS D 4 22  ? 117.564 123.290 149.963 1.00 131.12 ? 22  CYS H SG  1 
ATOM   9002  N N   . LYS D 4 23  ? 121.117 123.423 151.184 1.00 90.22  ? 23  LYS H N   1 
ATOM   9003  C CA  . LYS D 4 23  ? 121.891 122.401 151.854 1.00 126.09 ? 23  LYS H CA  1 
ATOM   9004  C C   . LYS D 4 23  ? 120.976 121.699 152.839 1.00 107.88 ? 23  LYS H C   1 
ATOM   9005  O O   . LYS D 4 23  ? 120.448 122.354 153.759 1.00 116.68 ? 23  LYS H O   1 
ATOM   9006  C CB  . LYS D 4 23  ? 123.117 123.011 152.529 1.00 193.30 ? 23  LYS H CB  1 
ATOM   9007  C CG  . LYS D 4 23  ? 124.125 121.997 153.052 1.00 227.09 ? 23  LYS H CG  1 
ATOM   9008  C CD  . LYS D 4 23  ? 125.435 122.611 153.485 1.00 276.10 ? 23  LYS H CD  1 
ATOM   9009  C CE  . LYS D 4 23  ? 126.458 121.581 153.911 1.00 309.43 ? 23  LYS H CE  1 
ATOM   9010  N NZ  . LYS D 4 23  ? 125.953 120.704 154.999 1.00 323.83 ? 23  LYS H NZ  1 
ATOM   9011  N N   . ALA D 4 24  ? 120.835 120.387 152.603 1.00 97.13  ? 24  ALA H N   1 
ATOM   9012  C CA  . ALA D 4 24  ? 120.091 119.506 153.475 1.00 124.39 ? 24  ALA H CA  1 
ATOM   9013  C C   . ALA D 4 24  ? 120.917 119.071 154.685 1.00 135.75 ? 24  ALA H C   1 
ATOM   9014  O O   . ALA D 4 24  ? 122.155 119.049 154.672 1.00 159.36 ? 24  ALA H O   1 
ATOM   9015  C CB  . ALA D 4 24  ? 119.633 118.285 152.725 1.00 118.10 ? 24  ALA H CB  1 
ATOM   9016  N N   . SER D 4 25  ? 120.163 118.710 155.729 1.00 120.24 ? 25  SER H N   1 
ATOM   9017  C CA  . SER D 4 25  ? 120.695 118.066 156.905 1.00 142.37 ? 25  SER H CA  1 
ATOM   9018  C C   . SER D 4 25  ? 119.605 117.276 157.597 1.00 114.70 ? 25  SER H C   1 
ATOM   9019  O O   . SER D 4 25  ? 118.417 117.557 157.456 1.00 211.35 ? 25  SER H O   1 
ATOM   9020  C CB  . SER D 4 25  ? 121.263 119.107 157.818 1.00 226.59 ? 25  SER H CB  1 
ATOM   9021  O OG  . SER D 4 25  ? 120.272 120.053 158.193 1.00 189.64 ? 25  SER H OG  1 
ATOM   9022  N N   . GLY D 4 26  ? 119.995 116.266 158.346 1.00 133.89 ? 26  GLY H N   1 
ATOM   9023  C CA  . GLY D 4 26  ? 119.046 115.637 159.251 1.00 149.49 ? 26  GLY H CA  1 
ATOM   9024  C C   . GLY D 4 26  ? 118.384 114.397 158.652 1.00 169.09 ? 26  GLY H C   1 
ATOM   9025  O O   . GLY D 4 26  ? 117.463 113.848 159.270 1.00 189.28 ? 26  GLY H O   1 
ATOM   9026  N N   . TYR D 4 27  ? 118.842 113.968 157.456 1.00 134.64 ? 27  TYR H N   1 
ATOM   9027  C CA  . TYR D 4 27  ? 118.281 112.780 156.827 1.00 130.08 ? 27  TYR H CA  1 
ATOM   9028  C C   . TYR D 4 27  ? 119.254 112.303 155.762 1.00 171.95 ? 27  TYR H C   1 
ATOM   9029  O O   . TYR D 4 27  ? 120.149 113.069 155.342 1.00 179.58 ? 27  TYR H O   1 
ATOM   9030  C CB  . TYR D 4 27  ? 116.897 113.040 156.226 1.00 134.63 ? 27  TYR H CB  1 
ATOM   9031  C CG  . TYR D 4 27  ? 116.886 113.983 155.018 1.00 132.21 ? 27  TYR H CG  1 
ATOM   9032  C CD1 . TYR D 4 27  ? 116.669 115.325 155.152 1.00 108.55 ? 27  TYR H CD1 1 
ATOM   9033  C CD2 . TYR D 4 27  ? 117.064 113.514 153.727 1.00 179.47 ? 27  TYR H CD2 1 
ATOM   9034  C CE1 . TYR D 4 27  ? 116.652 116.171 154.063 1.00 99.22  ? 27  TYR H CE1 1 
ATOM   9035  C CE2 . TYR D 4 27  ? 117.053 114.336 152.627 1.00 118.59 ? 27  TYR H CE2 1 
ATOM   9036  C CZ  . TYR D 4 27  ? 116.853 115.669 152.802 1.00 119.68 ? 27  TYR H CZ  1 
ATOM   9037  O OH  . TYR D 4 27  ? 116.850 116.402 151.679 1.00 144.56 ? 27  TYR H OH  1 
ATOM   9038  N N   . THR D 4 28  ? 119.037 111.022 155.363 1.00 153.91 ? 28  THR H N   1 
ATOM   9039  C CA  . THR D 4 28  ? 119.821 110.337 154.332 1.00 132.31 ? 28  THR H CA  1 
ATOM   9040  C C   . THR D 4 28  ? 119.562 110.953 152.958 1.00 111.60 ? 28  THR H C   1 
ATOM   9041  O O   . THR D 4 28  ? 118.522 110.694 152.391 1.00 176.54 ? 28  THR H O   1 
ATOM   9042  C CB  . THR D 4 28  ? 119.471 108.848 154.234 1.00 170.20 ? 28  THR H CB  1 
ATOM   9043  O OG1 . THR D 4 28  ? 119.487 108.236 155.531 1.00 206.86 ? 28  THR H OG1 1 
ATOM   9044  C CG2 . THR D 4 28  ? 120.404 108.153 153.256 1.00 231.98 ? 28  THR H CG2 1 
ATOM   9045  N N   . PHE D 4 29  ? 120.457 111.766 152.405 1.00 137.67 ? 29  PHE H N   1 
ATOM   9046  C CA  . PHE D 4 29  ? 120.084 112.743 151.382 1.00 117.09 ? 29  PHE H CA  1 
ATOM   9047  C C   . PHE D 4 29  ? 119.533 112.138 150.105 1.00 113.75 ? 29  PHE H C   1 
ATOM   9048  O O   . PHE D 4 29  ? 118.674 112.717 149.486 1.00 146.76 ? 29  PHE H O   1 
ATOM   9049  C CB  . PHE D 4 29  ? 121.325 113.489 150.954 1.00 129.18 ? 29  PHE H CB  1 
ATOM   9050  C CG  . PHE D 4 29  ? 121.127 114.607 149.981 1.00 89.53  ? 29  PHE H CG  1 
ATOM   9051  C CD1 . PHE D 4 29  ? 120.206 115.600 150.201 1.00 99.48  ? 29  PHE H CD1 1 
ATOM   9052  C CD2 . PHE D 4 29  ? 121.915 114.677 148.853 1.00 88.90  ? 29  PHE H CD2 1 
ATOM   9053  C CE1 . PHE D 4 29  ? 120.077 116.649 149.292 1.00 124.86 ? 29  PHE H CE1 1 
ATOM   9054  C CE2 . PHE D 4 29  ? 121.791 115.728 147.960 1.00 81.06  ? 29  PHE H CE2 1 
ATOM   9055  C CZ  . PHE D 4 29  ? 120.868 116.721 148.172 1.00 77.81  ? 29  PHE H CZ  1 
ATOM   9056  N N   . THR D 4 30  ? 120.033 110.973 149.726 1.00 114.16 ? 30  THR H N   1 
ATOM   9057  C CA  . THR D 4 30  ? 119.624 110.319 148.513 1.00 116.79 ? 30  THR H CA  1 
ATOM   9058  C C   . THR D 4 30  ? 118.234 109.677 148.597 1.00 152.07 ? 30  THR H C   1 
ATOM   9059  O O   . THR D 4 30  ? 117.703 109.311 147.539 1.00 216.93 ? 30  THR H O   1 
ATOM   9060  C CB  . THR D 4 30  ? 120.670 109.269 148.158 1.00 185.57 ? 30  THR H CB  1 
ATOM   9061  O OG1 . THR D 4 30  ? 120.717 108.287 149.224 1.00 154.51 ? 30  THR H OG1 1 
ATOM   9062  C CG2 . THR D 4 30  ? 121.982 109.965 147.825 1.00 182.99 ? 30  THR H CG2 1 
ATOM   9063  N N   . ASN D 4 31  ? 117.643 109.517 149.801 1.00 89.94  ? 31  ASN H N   1 
ATOM   9064  C CA  . ASN D 4 31  ? 116.360 108.828 149.924 1.00 110.64 ? 31  ASN H CA  1 
ATOM   9065  C C   . ASN D 4 31  ? 115.174 109.650 149.446 1.00 84.76  ? 31  ASN H C   1 
ATOM   9066  O O   . ASN D 4 31  ? 114.121 109.066 149.226 1.00 121.43 ? 31  ASN H O   1 
ATOM   9067  C CB  . ASN D 4 31  ? 115.973 108.371 151.333 1.00 114.97 ? 31  ASN H CB  1 
ATOM   9068  C CG  . ASN D 4 31  ? 116.637 107.050 151.710 1.00 200.70 ? 31  ASN H CG  1 
ATOM   9069  O OD1 . ASN D 4 31  ? 117.397 106.429 150.948 1.00 143.88 ? 31  ASN H OD1 1 
ATOM   9070  N ND2 . ASN D 4 31  ? 116.355 106.606 152.926 1.00 286.67 ? 31  ASN H ND2 1 
ATOM   9071  N N   . TYR D 4 32  ? 115.321 110.956 149.276 1.00 75.93  ? 32  TYR H N   1 
ATOM   9072  C CA  . TYR D 4 32  ? 114.167 111.809 149.027 1.00 82.48  ? 32  TYR H CA  1 
ATOM   9073  C C   . TYR D 4 32  ? 114.455 112.836 147.961 1.00 71.51  ? 32  TYR H C   1 
ATOM   9074  O O   . TYR D 4 32  ? 115.496 113.497 147.959 1.00 93.01  ? 32  TYR H O   1 
ATOM   9075  C CB  . TYR D 4 32  ? 113.809 112.586 150.294 1.00 78.85  ? 32  TYR H CB  1 
ATOM   9076  C CG  . TYR D 4 32  ? 113.474 111.669 151.445 1.00 79.59  ? 32  TYR H CG  1 
ATOM   9077  C CD1 . TYR D 4 32  ? 112.209 111.165 151.587 1.00 104.80 ? 32  TYR H CD1 1 
ATOM   9078  C CD2 . TYR D 4 32  ? 114.415 111.280 152.361 1.00 106.03 ? 32  TYR H CD2 1 
ATOM   9079  C CE1 . TYR D 4 32  ? 111.871 110.321 152.626 1.00 148.49 ? 32  TYR H CE1 1 
ATOM   9080  C CE2 . TYR D 4 32  ? 114.105 110.423 153.408 1.00 140.23 ? 32  TYR H CE2 1 
ATOM   9081  C CZ  . TYR D 4 32  ? 112.825 109.945 153.546 1.00 172.30 ? 32  TYR H CZ  1 
ATOM   9082  O OH  . TYR D 4 32  ? 112.501 109.111 154.569 1.00 264.80 ? 32  TYR H OH  1 
ATOM   9083  N N   . TRP D 4 33  ? 113.512 113.001 147.067 1.00 65.59  ? 33  TRP H N   1 
ATOM   9084  C CA  . TRP D 4 33  ? 113.797 113.948 146.018 1.00 68.73  ? 33  TRP H CA  1 
ATOM   9085  C C   . TRP D 4 33  ? 113.600 115.356 146.546 1.00 65.43  ? 33  TRP H C   1 
ATOM   9086  O O   . TRP D 4 33  ? 112.881 115.565 147.510 1.00 74.97  ? 33  TRP H O   1 
ATOM   9087  C CB  . TRP D 4 33  ? 112.848 113.810 144.847 1.00 74.06  ? 33  TRP H CB  1 
ATOM   9088  C CG  . TRP D 4 33  ? 112.874 112.558 144.067 1.00 60.72  ? 33  TRP H CG  1 
ATOM   9089  C CD1 . TRP D 4 33  ? 112.968 111.310 144.518 1.00 65.63  ? 33  TRP H CD1 1 
ATOM   9090  C CD2 . TRP D 4 33  ? 112.725 112.491 142.650 1.00 63.16  ? 33  TRP H CD2 1 
ATOM   9091  N NE1 . TRP D 4 33  ? 112.922 110.465 143.449 1.00 93.92  ? 33  TRP H NE1 1 
ATOM   9092  C CE2 . TRP D 4 33  ? 112.762 111.168 142.295 1.00 69.51  ? 33  TRP H CE2 1 
ATOM   9093  C CE3 . TRP D 4 33  ? 112.561 113.430 141.656 1.00 69.09  ? 33  TRP H CE3 1 
ATOM   9094  C CZ2 . TRP D 4 33  ? 112.642 110.746 140.993 1.00 76.31  ? 33  TRP H CZ2 1 
ATOM   9095  C CZ3 . TRP D 4 33  ? 112.455 113.030 140.371 1.00 67.61  ? 33  TRP H CZ3 1 
ATOM   9096  C CH2 . TRP D 4 33  ? 112.467 111.700 140.054 1.00 74.44  ? 33  TRP H CH2 1 
ATOM   9097  N N   . MET D 4 34  ? 114.194 116.298 145.837 1.00 65.73  ? 34  MET H N   1 
ATOM   9098  C CA  . MET D 4 34  ? 114.248 117.685 146.236 1.00 66.47  ? 34  MET H CA  1 
ATOM   9099  C C   . MET D 4 34  ? 113.483 118.520 145.216 1.00 51.66  ? 34  MET H C   1 
ATOM   9100  O O   . MET D 4 34  ? 113.688 118.415 144.017 1.00 49.34  ? 34  MET H O   1 
ATOM   9101  C CB  . MET D 4 34  ? 115.728 118.119 146.299 1.00 68.96  ? 34  MET H CB  1 
ATOM   9102  C CG  . MET D 4 34  ? 115.884 119.427 146.971 1.00 63.44  ? 34  MET H CG  1 
ATOM   9103  S SD  . MET D 4 34  ? 115.473 119.029 148.663 1.00 121.89 ? 34  MET H SD  1 
ATOM   9104  C CE  . MET D 4 34  ? 116.913 118.028 149.023 1.00 134.80 ? 34  MET H CE  1 
ATOM   9105  N N   . HIS D 4 35  ? 112.600 119.373 145.670 1.00 46.94  ? 35  HIS H N   1 
ATOM   9106  C CA  . HIS D 4 35  ? 111.783 120.170 144.767 1.00 60.38  ? 35  HIS H CA  1 
ATOM   9107  C C   . HIS D 4 35  ? 112.113 121.670 144.931 1.00 80.10  ? 35  HIS H C   1 
ATOM   9108  O O   . HIS D 4 35  ? 112.563 122.128 145.993 1.00 74.92  ? 35  HIS H O   1 
ATOM   9109  C CB  . HIS D 4 35  ? 110.306 120.024 145.107 1.00 55.69  ? 35  HIS H CB  1 
ATOM   9110  C CG  . HIS D 4 35  ? 109.829 118.681 145.225 1.00 50.33  ? 35  HIS H CG  1 
ATOM   9111  N ND1 . HIS D 4 35  ? 108.921 118.286 144.309 1.00 55.29  ? 35  HIS H ND1 1 
ATOM   9112  C CD2 . HIS D 4 35  ? 110.058 117.612 146.037 1.00 60.82  ? 35  HIS H CD2 1 
ATOM   9113  C CE1 . HIS D 4 35  ? 108.596 117.000 144.600 1.00 72.70  ? 35  HIS H CE1 1 
ATOM   9114  N NE2 . HIS D 4 35  ? 109.279 116.559 145.633 1.00 55.26  ? 35  HIS H NE2 1 
ATOM   9115  N N   . TRP D 4 36  ? 111.866 122.453 143.870 1.00 69.83  ? 36  TRP H N   1 
ATOM   9116  C CA  . TRP D 4 36  ? 112.041 123.898 143.832 1.00 54.35  ? 36  TRP H CA  1 
ATOM   9117  C C   . TRP D 4 36  ? 110.719 124.546 143.476 1.00 61.93  ? 36  TRP H C   1 
ATOM   9118  O O   . TRP D 4 36  ? 110.129 124.258 142.448 1.00 102.48 ? 36  TRP H O   1 
ATOM   9119  C CB  . TRP D 4 36  ? 113.092 124.272 142.769 1.00 78.60  ? 36  TRP H CB  1 
ATOM   9120  C CG  . TRP D 4 36  ? 114.433 123.862 143.313 1.00 92.03  ? 36  TRP H CG  1 
ATOM   9121  C CD1 . TRP D 4 36  ? 115.028 122.655 143.194 1.00 89.23  ? 36  TRP H CD1 1 
ATOM   9122  C CD2 . TRP D 4 36  ? 115.318 124.647 144.101 1.00 65.63  ? 36  TRP H CD2 1 
ATOM   9123  N NE1 . TRP D 4 36  ? 116.199 122.650 143.861 1.00 85.87  ? 36  TRP H NE1 1 
ATOM   9124  C CE2 . TRP D 4 36  ? 116.400 123.863 144.421 1.00 66.31  ? 36  TRP H CE2 1 
ATOM   9125  C CE3 . TRP D 4 36  ? 115.285 125.933 144.535 1.00 71.78  ? 36  TRP H CE3 1 
ATOM   9126  C CZ2 . TRP D 4 36  ? 117.471 124.299 145.159 1.00 83.46  ? 36  TRP H CZ2 1 
ATOM   9127  C CZ3 . TRP D 4 36  ? 116.334 126.385 145.266 1.00 120.66 ? 36  TRP H CZ3 1 
ATOM   9128  C CH2 . TRP D 4 36  ? 117.423 125.577 145.578 1.00 109.64 ? 36  TRP H CH2 1 
ATOM   9129  N N   . VAL D 4 37  ? 110.228 125.431 144.307 1.00 71.34  ? 37  VAL H N   1 
ATOM   9130  C CA  . VAL D 4 37  ? 108.983 126.128 144.088 1.00 56.06  ? 37  VAL H CA  1 
ATOM   9131  C C   . VAL D 4 37  ? 109.316 127.614 144.233 1.00 66.53  ? 37  VAL H C   1 
ATOM   9132  O O   . VAL D 4 37  ? 110.188 128.050 144.972 1.00 56.71  ? 37  VAL H O   1 
ATOM   9133  C CB  . VAL D 4 37  ? 108.036 125.669 145.201 1.00 65.90  ? 37  VAL H CB  1 
ATOM   9134  C CG1 . VAL D 4 37  ? 106.774 126.477 145.413 1.00 85.19  ? 37  VAL H CG1 1 
ATOM   9135  C CG2 . VAL D 4 37  ? 107.631 124.266 144.953 1.00 82.32  ? 37  VAL H CG2 1 
ATOM   9136  N N   . ARG D 4 38  ? 108.568 128.425 143.533 1.00 84.90  ? 38  ARG H N   1 
ATOM   9137  C CA  . ARG D 4 38  ? 108.757 129.858 143.426 1.00 60.62  ? 38  ARG H CA  1 
ATOM   9138  C C   . ARG D 4 38  ? 107.477 130.598 143.845 1.00 69.84  ? 38  ARG H C   1 
ATOM   9139  O O   . ARG D 4 38  ? 106.339 130.122 143.722 1.00 90.47  ? 38  ARG H O   1 
ATOM   9140  C CB  . ARG D 4 38  ? 108.939 129.980 141.939 1.00 70.12  ? 38  ARG H CB  1 
ATOM   9141  C CG  . ARG D 4 38  ? 109.035 131.395 141.402 1.00 96.94  ? 38  ARG H CG  1 
ATOM   9142  C CD  . ARG D 4 38  ? 108.547 131.562 139.977 1.00 92.25  ? 38  ARG H CD  1 
ATOM   9143  N NE  . ARG D 4 38  ? 109.636 131.954 139.081 1.00 73.19  ? 38  ARG H NE  1 
ATOM   9144  C CZ  . ARG D 4 38  ? 109.410 132.324 137.844 1.00 116.64 ? 38  ARG H CZ  1 
ATOM   9145  N NH1 . ARG D 4 38  ? 110.452 132.772 137.144 1.00 137.62 ? 38  ARG H NH1 1 
ATOM   9146  N NH2 . ARG D 4 38  ? 108.153 132.259 137.350 1.00 104.72 ? 38  ARG H NH2 1 
ATOM   9147  N N   . LEU D 4 39  ? 107.652 131.786 144.369 1.00 77.18  ? 39  LEU H N   1 
ATOM   9148  C CA  . LEU D 4 39  ? 106.528 132.600 144.777 1.00 83.28  ? 39  LEU H CA  1 
ATOM   9149  C C   . LEU D 4 39  ? 106.730 134.055 144.294 1.00 97.87  ? 39  LEU H C   1 
ATOM   9150  O O   . LEU D 4 39  ? 107.330 134.905 144.985 1.00 68.65  ? 39  LEU H O   1 
ATOM   9151  C CB  . LEU D 4 39  ? 106.469 132.461 146.285 1.00 77.23  ? 39  LEU H CB  1 
ATOM   9152  C CG  . LEU D 4 39  ? 105.454 133.367 146.939 1.00 102.89 ? 39  LEU H CG  1 
ATOM   9153  C CD1 . LEU D 4 39  ? 104.080 132.975 146.442 1.00 127.30 ? 39  LEU H CD1 1 
ATOM   9154  C CD2 . LEU D 4 39  ? 105.578 133.303 148.442 1.00 127.17 ? 39  LEU H CD2 1 
ATOM   9155  N N   . ARG D 4 40  ? 106.237 134.292 143.051 1.00 118.42 ? 40  ARG H N   1 
ATOM   9156  C CA  . ARG D 4 40  ? 106.088 135.604 142.433 1.00 116.63 ? 40  ARG H CA  1 
ATOM   9157  C C   . ARG D 4 40  ? 105.263 136.422 143.422 1.00 128.83 ? 40  ARG H C   1 
ATOM   9158  O O   . ARG D 4 40  ? 104.281 135.905 143.940 1.00 137.27 ? 40  ARG H O   1 
ATOM   9159  C CB  . ARG D 4 40  ? 105.369 135.516 141.066 1.00 197.05 ? 40  ARG H CB  1 
ATOM   9160  C CG  . ARG D 4 40  ? 106.068 134.862 139.864 1.00 148.80 ? 40  ARG H CG  1 
ATOM   9161  C CD  . ARG D 4 40  ? 107.320 135.571 139.428 1.00 176.07 ? 40  ARG H CD  1 
ATOM   9162  N NE  . ARG D 4 40  ? 107.324 137.021 139.630 1.00 267.26 ? 40  ARG H NE  1 
ATOM   9163  C CZ  . ARG D 4 40  ? 106.551 137.901 138.989 1.00 346.22 ? 40  ARG H CZ  1 
ATOM   9164  N NH1 . ARG D 4 40  ? 106.615 139.189 139.291 1.00 361.40 ? 40  ARG H NH1 1 
ATOM   9165  N NH2 . ARG D 4 40  ? 105.705 137.502 138.053 1.00 362.01 ? 40  ARG H NH2 1 
ATOM   9166  N N   . PRO D 4 41  ? 105.606 137.680 143.765 1.00 175.49 ? 41  PRO H N   1 
ATOM   9167  C CA  . PRO D 4 41  ? 104.784 138.463 144.696 1.00 190.03 ? 41  PRO H CA  1 
ATOM   9168  C C   . PRO D 4 41  ? 103.322 138.643 144.279 1.00 195.75 ? 41  PRO H C   1 
ATOM   9169  O O   . PRO D 4 41  ? 103.041 138.989 143.123 1.00 158.21 ? 41  PRO H O   1 
ATOM   9170  C CB  . PRO D 4 41  ? 105.507 139.811 144.702 1.00 266.04 ? 41  PRO H CB  1 
ATOM   9171  C CG  . PRO D 4 41  ? 106.947 139.436 144.404 1.00 271.86 ? 41  PRO H CG  1 
ATOM   9172  C CD  . PRO D 4 41  ? 106.805 138.398 143.319 1.00 214.97 ? 41  PRO H CD  1 
ATOM   9173  N N   . GLY D 4 42  ? 102.431 138.375 145.260 1.00 227.51 ? 42  GLY H N   1 
ATOM   9174  C CA  . GLY D 4 42  ? 100.978 138.469 145.157 1.00 242.47 ? 42  GLY H CA  1 
ATOM   9175  C C   . GLY D 4 42  ? 100.331 137.623 144.060 1.00 235.24 ? 42  GLY H C   1 
ATOM   9176  O O   . GLY D 4 42  ? 99.245  137.968 143.608 1.00 298.19 ? 42  GLY H O   1 
ATOM   9177  N N   . GLN D 4 43  ? 100.981 136.525 143.639 1.00 217.01 ? 43  GLN H N   1 
ATOM   9178  C CA  . GLN D 4 43  ? 100.619 135.787 142.429 1.00 187.40 ? 43  GLN H CA  1 
ATOM   9179  C C   . GLN D 4 43  ? 100.665 134.258 142.622 1.00 178.98 ? 43  GLN H C   1 
ATOM   9180  O O   . GLN D 4 43  ? 100.492 133.512 141.654 1.00 166.99 ? 43  GLN H O   1 
ATOM   9181  C CB  . GLN D 4 43  ? 101.523 136.304 141.306 1.00 144.22 ? 43  GLN H CB  1 
ATOM   9182  C CG  . GLN D 4 43  ? 101.392 135.557 139.977 1.00 181.99 ? 43  GLN H CG  1 
ATOM   9183  C CD  . GLN D 4 43  ? 102.227 136.115 138.853 1.00 276.37 ? 43  GLN H CD  1 
ATOM   9184  O OE1 . GLN D 4 43  ? 102.589 137.290 138.847 1.00 341.79 ? 43  GLN H OE1 1 
ATOM   9185  N NE2 . GLN D 4 43  ? 102.537 135.263 137.882 1.00 298.36 ? 43  GLN H NE2 1 
ATOM   9186  N N   . GLY D 4 44  ? 100.874 133.767 143.854 1.00 178.40 ? 44  GLY H N   1 
ATOM   9187  C CA  . GLY D 4 44  ? 100.663 132.363 144.173 1.00 173.87 ? 44  GLY H CA  1 
ATOM   9188  C C   . GLY D 4 44  ? 101.855 131.482 143.810 1.00 126.33 ? 44  GLY H C   1 
ATOM   9189  O O   . GLY D 4 44  ? 102.587 131.784 142.876 1.00 101.33 ? 44  GLY H O   1 
ATOM   9190  N N   . LEU D 4 45  ? 102.018 130.386 144.563 1.00 101.95 ? 45  LEU H N   1 
ATOM   9191  C CA  . LEU D 4 45  ? 103.150 129.478 144.420 1.00 91.90  ? 45  LEU H CA  1 
ATOM   9192  C C   . LEU D 4 45  ? 103.094 128.761 143.064 1.00 123.74 ? 45  LEU H C   1 
ATOM   9193  O O   . LEU D 4 45  ? 102.008 128.530 142.500 1.00 127.47 ? 45  LEU H O   1 
ATOM   9194  C CB  . LEU D 4 45  ? 103.090 128.399 145.491 1.00 74.51  ? 45  LEU H CB  1 
ATOM   9195  C CG  . LEU D 4 45  ? 103.203 128.920 146.892 1.00 81.87  ? 45  LEU H CG  1 
ATOM   9196  C CD1 . LEU D 4 45  ? 102.614 127.961 147.875 1.00 79.18  ? 45  LEU H CD1 1 
ATOM   9197  C CD2 . LEU D 4 45  ? 104.675 129.128 147.131 1.00 87.74  ? 45  LEU H CD2 1 
ATOM   9198  N N   . GLU D 4 46  ? 104.287 128.409 142.559 1.00 88.57  ? 46  GLU H N   1 
ATOM   9199  C CA  . GLU D 4 46  ? 104.480 127.736 141.285 1.00 76.36  ? 46  GLU H CA  1 
ATOM   9200  C C   . GLU D 4 46  ? 105.669 126.802 141.436 1.00 80.12  ? 46  GLU H C   1 
ATOM   9201  O O   . GLU D 4 46  ? 106.724 127.188 141.962 1.00 83.03  ? 46  GLU H O   1 
ATOM   9202  C CB  . GLU D 4 46  ? 104.802 128.804 140.226 1.00 120.43 ? 46  GLU H CB  1 
ATOM   9203  C CG  . GLU D 4 46  ? 105.039 128.287 138.806 1.00 151.29 ? 46  GLU H CG  1 
ATOM   9204  C CD  . GLU D 4 46  ? 105.217 129.409 137.787 1.00 260.14 ? 46  GLU H CD  1 
ATOM   9205  O OE1 . GLU D 4 46  ? 105.816 130.474 138.126 1.00 277.25 ? 46  GLU H OE1 1 
ATOM   9206  O OE2 . GLU D 4 46  ? 104.752 129.220 136.647 1.00 367.61 ? 46  GLU H OE2 1 
ATOM   9207  N N   . TRP D 4 47  ? 105.528 125.589 140.932 1.00 74.69  ? 47  TRP H N   1 
ATOM   9208  C CA  . TRP D 4 47  ? 106.566 124.601 141.150 1.00 63.89  ? 47  TRP H CA  1 
ATOM   9209  C C   . TRP D 4 47  ? 107.433 124.496 139.917 1.00 85.94  ? 47  TRP H C   1 
ATOM   9210  O O   . TRP D 4 47  ? 106.921 124.424 138.797 1.00 89.78  ? 47  TRP H O   1 
ATOM   9211  C CB  . TRP D 4 47  ? 105.805 123.296 141.325 1.00 72.57  ? 47  TRP H CB  1 
ATOM   9212  C CG  . TRP D 4 47  ? 106.529 121.997 141.593 1.00 65.14  ? 47  TRP H CG  1 
ATOM   9213  C CD1 . TRP D 4 47  ? 106.849 121.448 142.805 1.00 56.65  ? 47  TRP H CD1 1 
ATOM   9214  C CD2 . TRP D 4 47  ? 106.966 121.019 140.632 1.00 53.06  ? 47  TRP H CD2 1 
ATOM   9215  N NE1 . TRP D 4 47  ? 107.479 120.244 142.671 1.00 38.44  ? 47  TRP H NE1 1 
ATOM   9216  C CE2 . TRP D 4 47  ? 107.537 119.967 141.351 1.00 46.46  ? 47  TRP H CE2 1 
ATOM   9217  C CE3 . TRP D 4 47  ? 106.943 120.939 139.253 1.00 53.05  ? 47  TRP H CE3 1 
ATOM   9218  C CZ2 . TRP D 4 47  ? 108.048 118.877 140.706 1.00 64.30  ? 47  TRP H CZ2 1 
ATOM   9219  C CZ3 . TRP D 4 47  ? 107.464 119.849 138.622 1.00 53.52  ? 47  TRP H CZ3 1 
ATOM   9220  C CH2 . TRP D 4 47  ? 107.992 118.833 139.338 1.00 57.60  ? 47  TRP H CH2 1 
ATOM   9221  N N   . ILE D 4 48  ? 108.732 124.484 140.112 1.00 70.27  ? 48  ILE H N   1 
ATOM   9222  C CA  . ILE D 4 48  ? 109.670 124.490 139.002 1.00 64.82  ? 48  ILE H CA  1 
ATOM   9223  C C   . ILE D 4 48  ? 109.973 123.053 138.570 1.00 59.49  ? 48  ILE H C   1 
ATOM   9224  O O   . ILE D 4 48  ? 109.830 122.678 137.434 1.00 67.55  ? 48  ILE H O   1 
ATOM   9225  C CB  . ILE D 4 48  ? 110.906 125.224 139.504 1.00 75.12  ? 48  ILE H CB  1 
ATOM   9226  C CG1 . ILE D 4 48  ? 110.515 126.653 139.858 1.00 75.37  ? 48  ILE H CG1 1 
ATOM   9227  C CG2 . ILE D 4 48  ? 112.061 125.104 138.549 1.00 61.89  ? 48  ILE H CG2 1 
ATOM   9228  C CD1 . ILE D 4 48  ? 111.721 127.373 140.366 1.00 122.33 ? 48  ILE H CD1 1 
ATOM   9229  N N   . GLY D 4 49  ? 110.397 122.215 139.479 1.00 61.45  ? 49  GLY H N   1 
ATOM   9230  C CA  . GLY D 4 49  ? 110.842 120.889 139.139 1.00 56.43  ? 49  GLY H CA  1 
ATOM   9231  C C   . GLY D 4 49  ? 111.419 120.215 140.376 1.00 58.09  ? 49  GLY H C   1 
ATOM   9232  O O   . GLY D 4 49  ? 111.585 120.825 141.446 1.00 69.19  ? 49  GLY H O   1 
ATOM   9233  N N   . GLU D 4 50  ? 111.751 118.952 140.176 1.00 44.57  ? 50  GLU H N   1 
ATOM   9234  C CA  . GLU D 4 50  ? 112.433 118.251 141.217 1.00 41.92  ? 50  GLU H CA  1 
ATOM   9235  C C   . GLU D 4 50  ? 113.526 117.351 140.678 1.00 43.73  ? 50  GLU H C   1 
ATOM   9236  O O   . GLU D 4 50  ? 113.557 116.991 139.478 1.00 53.35  ? 50  GLU H O   1 
ATOM   9237  C CB  . GLU D 4 50  ? 111.418 117.361 141.843 1.00 54.14  ? 50  GLU H CB  1 
ATOM   9238  C CG  . GLU D 4 50  ? 110.753 116.410 140.882 1.00 62.37  ? 50  GLU H CG  1 
ATOM   9239  C CD  . GLU D 4 50  ? 109.846 115.319 141.495 1.00 71.45  ? 50  GLU H CD  1 
ATOM   9240  O OE1 . GLU D 4 50  ? 109.172 115.533 142.495 1.00 49.76  ? 50  GLU H OE1 1 
ATOM   9241  O OE2 . GLU D 4 50  ? 109.767 114.238 140.925 1.00 94.68  ? 50  GLU H OE2 1 
ATOM   9242  N N   . ILE D 4 51  ? 114.387 116.980 141.606 1.00 36.93  ? 51  ILE H N   1 
ATOM   9243  C CA  . ILE D 4 51  ? 115.616 116.318 141.251 1.00 51.36  ? 51  ILE H CA  1 
ATOM   9244  C C   . ILE D 4 51  ? 115.723 115.133 142.174 1.00 59.49  ? 51  ILE H C   1 
ATOM   9245  O O   . ILE D 4 51  ? 115.335 115.259 143.309 1.00 81.36  ? 51  ILE H O   1 
ATOM   9246  C CB  . ILE D 4 51  ? 116.794 117.307 141.388 1.00 61.31  ? 51  ILE H CB  1 
ATOM   9247  C CG1 . ILE D 4 51  ? 118.198 116.726 141.411 1.00 76.61  ? 51  ILE H CG1 1 
ATOM   9248  C CG2 . ILE D 4 51  ? 116.683 118.114 142.631 1.00 74.86  ? 51  ILE H CG2 1 
ATOM   9249  C CD1 . ILE D 4 51  ? 118.607 116.338 140.034 1.00 107.99 ? 51  ILE H CD1 1 
ATOM   9250  N N   . ASP D 4 52  ? 116.270 114.047 141.688 1.00 60.77  ? 52  ASP H N   1 
ATOM   9251  C CA  . ASP D 4 52  ? 116.581 112.926 142.519 1.00 69.13  ? 52  ASP H CA  1 
ATOM   9252  C C   . ASP D 4 52  ? 118.097 112.936 142.820 1.00 95.42  ? 52  ASP H C   1 
ATOM   9253  O O   . ASP D 4 52  ? 118.956 112.721 141.955 1.00 118.12 ? 52  ASP H O   1 
ATOM   9254  C CB  . ASP D 4 52  ? 116.145 111.687 141.773 1.00 75.57  ? 52  ASP H CB  1 
ATOM   9255  C CG  . ASP D 4 52  ? 116.327 110.412 142.575 1.00 127.21 ? 52  ASP H CG  1 
ATOM   9256  O OD1 . ASP D 4 52  ? 117.134 110.412 143.570 1.00 135.43 ? 52  ASP H OD1 1 
ATOM   9257  O OD2 . ASP D 4 52  ? 115.666 109.412 142.199 1.00 154.78 ? 52  ASP H OD2 1 
ATOM   9258  N N   . PRO D 4 53  ? 118.530 113.095 144.069 1.00 81.03  ? 53  PRO H N   1 
ATOM   9259  C CA  . PRO D 4 53  ? 119.941 113.075 144.344 1.00 74.67  ? 53  PRO H CA  1 
ATOM   9260  C C   . PRO D 4 53  ? 120.659 111.771 144.054 1.00 108.43 ? 53  PRO H C   1 
ATOM   9261  O O   . PRO D 4 53  ? 121.894 111.791 144.040 1.00 194.35 ? 53  PRO H O   1 
ATOM   9262  C CB  . PRO D 4 53  ? 120.005 113.172 145.880 1.00 93.34  ? 53  PRO H CB  1 
ATOM   9263  C CG  . PRO D 4 53  ? 118.735 113.893 146.198 1.00 147.50 ? 53  PRO H CG  1 
ATOM   9264  C CD  . PRO D 4 53  ? 117.734 113.224 145.286 1.00 112.68 ? 53  PRO H CD  1 
ATOM   9265  N N   . SER D 4 54  ? 119.924 110.659 143.872 1.00 110.76 ? 54  SER H N   1 
ATOM   9266  C CA  . SER D 4 54  ? 120.561 109.365 143.765 1.00 107.93 ? 54  SER H CA  1 
ATOM   9267  C C   . SER D 4 54  ? 121.152 109.172 142.375 1.00 130.94 ? 54  SER H C   1 
ATOM   9268  O O   . SER D 4 54  ? 121.980 108.268 142.202 1.00 224.45 ? 54  SER H O   1 
ATOM   9269  C CB  . SER D 4 54  ? 119.636 108.247 144.167 1.00 130.57 ? 54  SER H CB  1 
ATOM   9270  O OG  . SER D 4 54  ? 118.475 108.202 143.362 1.00 209.48 ? 54  SER H OG  1 
ATOM   9271  N N   . ASP D 4 55  ? 120.743 109.982 141.394 1.00 108.91 ? 55  ASP H N   1 
ATOM   9272  C CA  . ASP D 4 55  ? 121.261 109.819 140.049 1.00 142.15 ? 55  ASP H CA  1 
ATOM   9273  C C   . ASP D 4 55  ? 121.143 111.085 139.224 1.00 122.55 ? 55  ASP H C   1 
ATOM   9274  O O   . ASP D 4 55  ? 121.307 111.003 137.998 1.00 154.33 ? 55  ASP H O   1 
ATOM   9275  C CB  . ASP D 4 55  ? 120.534 108.651 139.337 1.00 175.77 ? 55  ASP H CB  1 
ATOM   9276  C CG  . ASP D 4 55  ? 119.008 108.680 139.206 1.00 158.69 ? 55  ASP H CG  1 
ATOM   9277  O OD1 . ASP D 4 55  ? 118.439 109.770 139.051 1.00 162.84 ? 55  ASP H OD1 1 
ATOM   9278  O OD2 . ASP D 4 55  ? 118.387 107.593 139.234 1.00 218.47 ? 55  ASP H OD2 1 
ATOM   9279  N N   . SER D 4 56  ? 120.841 112.211 139.859 1.00 75.18  ? 56  SER H N   1 
ATOM   9280  C CA  . SER D 4 56  ? 120.686 113.463 139.133 1.00 96.41  ? 56  SER H CA  1 
ATOM   9281  C C   . SER D 4 56  ? 119.633 113.540 138.002 1.00 94.64  ? 56  SER H C   1 
ATOM   9282  O O   . SER D 4 56  ? 119.662 114.529 137.253 1.00 117.46 ? 56  SER H O   1 
ATOM   9283  C CB  . SER D 4 56  ? 122.061 113.939 138.652 1.00 157.44 ? 56  SER H CB  1 
ATOM   9284  O OG  . SER D 4 56  ? 123.030 113.877 139.710 1.00 188.51 ? 56  SER H OG  1 
ATOM   9285  N N   . TYR D 4 57  ? 118.685 112.580 137.883 1.00 92.00  ? 57  TYR H N   1 
ATOM   9286  C CA  . TYR D 4 57  ? 117.483 112.729 137.057 1.00 96.58  ? 57  TYR H CA  1 
ATOM   9287  C C   . TYR D 4 57  ? 116.638 113.882 137.569 1.00 85.60  ? 57  TYR H C   1 
ATOM   9288  O O   . TYR D 4 57  ? 116.505 113.996 138.787 1.00 85.86  ? 57  TYR H O   1 
ATOM   9289  C CB  . TYR D 4 57  ? 116.484 111.565 137.088 1.00 77.97  ? 57  TYR H CB  1 
ATOM   9290  C CG  . TYR D 4 57  ? 115.311 111.781 136.133 1.00 64.57  ? 57  TYR H CG  1 
ATOM   9291  C CD1 . TYR D 4 57  ? 115.483 111.932 134.795 1.00 93.81  ? 57  TYR H CD1 1 
ATOM   9292  C CD2 . TYR D 4 57  ? 114.026 111.903 136.556 1.00 94.06  ? 57  TYR H CD2 1 
ATOM   9293  C CE1 . TYR D 4 57  ? 114.435 112.145 133.918 1.00 73.23  ? 57  TYR H CE1 1 
ATOM   9294  C CE2 . TYR D 4 57  ? 112.950 112.127 135.706 1.00 73.54  ? 57  TYR H CE2 1 
ATOM   9295  C CZ  . TYR D 4 57  ? 113.155 112.232 134.358 1.00 76.22  ? 57  TYR H CZ  1 
ATOM   9296  O OH  . TYR D 4 57  ? 112.272 112.423 133.338 1.00 88.24  ? 57  TYR H OH  1 
ATOM   9297  N N   . SER D 4 58  ? 116.070 114.699 136.665 1.00 76.42  ? 58  SER H N   1 
ATOM   9298  C CA  . SER D 4 58  ? 115.189 115.753 137.147 1.00 71.29  ? 58  SER H CA  1 
ATOM   9299  C C   . SER D 4 58  ? 114.068 115.998 136.155 1.00 53.17  ? 58  SER H C   1 
ATOM   9300  O O   . SER D 4 58  ? 114.250 115.816 134.948 1.00 77.36  ? 58  SER H O   1 
ATOM   9301  C CB  . SER D 4 58  ? 115.953 117.011 137.439 1.00 82.25  ? 58  SER H CB  1 
ATOM   9302  O OG  . SER D 4 58  ? 116.833 117.341 136.376 1.00 105.86 ? 58  SER H OG  1 
ATOM   9303  N N   . TYR D 4 59  ? 112.947 116.423 136.696 1.00 39.07  ? 59  TYR H N   1 
ATOM   9304  C CA  . TYR D 4 59  ? 111.712 116.524 135.951 1.00 48.81  ? 59  TYR H CA  1 
ATOM   9305  C C   . TYR D 4 59  ? 111.189 117.945 136.153 1.00 62.43  ? 59  TYR H C   1 
ATOM   9306  O O   . TYR D 4 59  ? 111.207 118.421 137.316 1.00 59.94  ? 59  TYR H O   1 
ATOM   9307  C CB  . TYR D 4 59  ? 110.828 115.362 136.482 1.00 47.18  ? 59  TYR H CB  1 
ATOM   9308  C CG  . TYR D 4 59  ? 109.474 115.266 135.808 1.00 48.74  ? 59  TYR H CG  1 
ATOM   9309  C CD1 . TYR D 4 59  ? 109.359 114.512 134.688 1.00 64.90  ? 59  TYR H CD1 1 
ATOM   9310  C CD2 . TYR D 4 59  ? 108.335 115.940 136.226 1.00 51.06  ? 59  TYR H CD2 1 
ATOM   9311  C CE1 . TYR D 4 59  ? 108.161 114.417 133.997 1.00 88.66  ? 59  TYR H CE1 1 
ATOM   9312  C CE2 . TYR D 4 59  ? 107.128 115.848 135.566 1.00 70.11  ? 59  TYR H CE2 1 
ATOM   9313  C CZ  . TYR D 4 59  ? 107.027 115.072 134.434 1.00 81.05  ? 59  TYR H CZ  1 
ATOM   9314  O OH  . TYR D 4 59  ? 105.867 114.917 133.723 1.00 84.65  ? 59  TYR H OH  1 
ATOM   9315  N N   . TYR D 4 60  ? 110.708 118.606 135.081 1.00 54.55  ? 60  TYR H N   1 
ATOM   9316  C CA  . TYR D 4 60  ? 110.493 120.053 135.196 1.00 63.72  ? 60  TYR H CA  1 
ATOM   9317  C C   . TYR D 4 60  ? 109.145 120.523 134.702 1.00 65.62  ? 60  TYR H C   1 
ATOM   9318  O O   . TYR D 4 60  ? 108.584 119.811 133.857 1.00 81.86  ? 60  TYR H O   1 
ATOM   9319  C CB  . TYR D 4 60  ? 111.397 120.914 134.345 1.00 61.22  ? 60  TYR H CB  1 
ATOM   9320  C CG  . TYR D 4 60  ? 112.851 120.737 134.659 1.00 74.32  ? 60  TYR H CG  1 
ATOM   9321  C CD1 . TYR D 4 60  ? 113.402 121.306 135.771 1.00 91.19  ? 60  TYR H CD1 1 
ATOM   9322  C CD2 . TYR D 4 60  ? 113.652 120.000 133.847 1.00 90.13  ? 60  TYR H CD2 1 
ATOM   9323  C CE1 . TYR D 4 60  ? 114.739 121.150 136.093 1.00 86.25  ? 60  TYR H CE1 1 
ATOM   9324  C CE2 . TYR D 4 60  ? 114.977 119.848 134.143 1.00 120.04 ? 60  TYR H CE2 1 
ATOM   9325  C CZ  . TYR D 4 60  ? 115.513 120.408 135.273 1.00 83.78  ? 60  TYR H CZ  1 
ATOM   9326  O OH  . TYR D 4 60  ? 116.812 120.185 135.465 1.00 136.34 ? 60  TYR H OH  1 
ATOM   9327  N N   . SER D 4 61  ? 108.652 121.696 135.209 1.00 46.62  ? 61  SER H N   1 
ATOM   9328  C CA  . SER D 4 61  ? 107.302 122.080 134.797 1.00 78.51  ? 61  SER H CA  1 
ATOM   9329  C C   . SER D 4 61  ? 107.382 122.574 133.377 1.00 101.78 ? 61  SER H C   1 
ATOM   9330  O O   . SER D 4 61  ? 108.476 122.876 132.984 1.00 95.46  ? 61  SER H O   1 
ATOM   9331  C CB  . SER D 4 61  ? 106.577 123.064 135.652 1.00 109.96 ? 61  SER H CB  1 
ATOM   9332  O OG  . SER D 4 61  ? 107.376 124.147 135.980 1.00 93.19  ? 61  SER H OG  1 
ATOM   9333  N N   . GLN D 4 62  ? 106.271 122.619 132.640 1.00 109.60 ? 62  GLN H N   1 
ATOM   9334  C CA  . GLN D 4 62  ? 106.388 122.950 131.229 1.00 131.86 ? 62  GLN H CA  1 
ATOM   9335  C C   . GLN D 4 62  ? 106.967 124.357 131.072 1.00 119.20 ? 62  GLN H C   1 
ATOM   9336  O O   . GLN D 4 62  ? 107.672 124.679 130.104 1.00 146.85 ? 62  GLN H O   1 
ATOM   9337  C CB  . GLN D 4 62  ? 105.014 122.803 130.581 1.00 203.63 ? 62  GLN H CB  1 
ATOM   9338  C CG  . GLN D 4 62  ? 105.066 122.708 129.060 1.00 278.25 ? 62  GLN H CG  1 
ATOM   9339  C CD  . GLN D 4 62  ? 105.686 121.415 128.588 1.00 263.50 ? 62  GLN H CD  1 
ATOM   9340  O OE1 . GLN D 4 62  ? 106.914 121.327 128.443 1.00 98.28  ? 62  GLN H OE1 1 
ATOM   9341  N NE2 . GLN D 4 62  ? 104.842 120.414 128.373 1.00 313.40 ? 62  GLN H NE2 1 
ATOM   9342  N N   . ASN D 4 63  ? 106.657 125.235 132.032 1.00 116.81 ? 63  ASN H N   1 
ATOM   9343  C CA  . ASN D 4 63  ? 107.063 126.639 131.960 1.00 138.49 ? 63  ASN H CA  1 
ATOM   9344  C C   . ASN D 4 63  ? 108.564 126.793 132.120 1.00 101.47 ? 63  ASN H C   1 
ATOM   9345  O O   . ASN D 4 63  ? 109.073 127.839 131.707 1.00 156.31 ? 63  ASN H O   1 
ATOM   9346  C CB  . ASN D 4 63  ? 106.360 127.546 132.983 1.00 124.33 ? 63  ASN H CB  1 
ATOM   9347  C CG  . ASN D 4 63  ? 104.838 127.494 132.870 1.00 201.11 ? 63  ASN H CG  1 
ATOM   9348  O OD1 . ASN D 4 63  ? 104.280 127.190 131.807 1.00 157.54 ? 63  ASN H OD1 1 
ATOM   9349  N ND2 . ASN D 4 63  ? 104.136 127.795 133.962 1.00 264.34 ? 63  ASN H ND2 1 
ATOM   9350  N N   . PHE D 4 64  ? 109.239 125.785 132.702 1.00 66.96  ? 64  PHE H N   1 
ATOM   9351  C CA  . PHE D 4 64  ? 110.638 125.927 133.096 1.00 89.14  ? 64  PHE H CA  1 
ATOM   9352  C C   . PHE D 4 64  ? 111.530 125.050 132.252 1.00 105.99 ? 64  PHE H C   1 
ATOM   9353  O O   . PHE D 4 64  ? 112.750 125.081 132.455 1.00 189.30 ? 64  PHE H O   1 
ATOM   9354  C CB  . PHE D 4 64  ? 110.922 125.729 134.594 1.00 89.39  ? 64  PHE H CB  1 
ATOM   9355  C CG  . PHE D 4 64  ? 110.382 126.879 135.401 1.00 92.35  ? 64  PHE H CG  1 
ATOM   9356  C CD1 . PHE D 4 64  ? 109.035 126.979 135.583 1.00 110.94 ? 64  PHE H CD1 1 
ATOM   9357  C CD2 . PHE D 4 64  ? 111.187 127.861 135.908 1.00 117.81 ? 64  PHE H CD2 1 
ATOM   9358  C CE1 . PHE D 4 64  ? 108.479 128.021 136.259 1.00 132.20 ? 64  PHE H CE1 1 
ATOM   9359  C CE2 . PHE D 4 64  ? 110.635 128.914 136.598 1.00 123.37 ? 64  PHE H CE2 1 
ATOM   9360  C CZ  . PHE D 4 64  ? 109.283 128.978 136.768 1.00 154.32 ? 64  PHE H CZ  1 
ATOM   9361  N N   . LYS D 4 65  ? 110.965 124.340 131.280 1.00 96.23  ? 65  LYS H N   1 
ATOM   9362  C CA  . LYS D 4 65  ? 111.754 123.347 130.580 1.00 128.48 ? 65  LYS H CA  1 
ATOM   9363  C C   . LYS D 4 65  ? 112.776 124.106 129.736 1.00 170.06 ? 65  LYS H C   1 
ATOM   9364  O O   . LYS D 4 65  ? 112.405 124.965 128.923 1.00 147.00 ? 65  LYS H O   1 
ATOM   9365  C CB  . LYS D 4 65  ? 110.795 122.444 129.828 1.00 125.07 ? 65  LYS H CB  1 
ATOM   9366  C CG  . LYS D 4 65  ? 111.416 121.142 129.379 1.00 173.41 ? 65  LYS H CG  1 
ATOM   9367  C CD  . LYS D 4 65  ? 110.358 120.143 128.915 1.00 204.77 ? 65  LYS H CD  1 
ATOM   9368  C CE  . LYS D 4 65  ? 109.276 119.825 129.933 1.00 150.15 ? 65  LYS H CE  1 
ATOM   9369  N NZ  . LYS D 4 65  ? 108.291 118.877 129.369 1.00 148.00 ? 65  LYS H NZ  1 
ATOM   9370  N N   . GLY D 4 66  ? 114.062 123.804 129.990 1.00 163.75 ? 66  GLY H N   1 
ATOM   9371  C CA  . GLY D 4 66  ? 115.164 124.534 129.378 1.00 174.83 ? 66  GLY H CA  1 
ATOM   9372  C C   . GLY D 4 66  ? 115.559 125.854 130.046 1.00 141.54 ? 66  GLY H C   1 
ATOM   9373  O O   . GLY D 4 66  ? 116.754 126.153 130.021 1.00 152.16 ? 66  GLY H O   1 
ATOM   9374  N N   . LYS D 4 67  ? 114.590 126.614 130.599 1.00 142.80 ? 67  LYS H N   1 
ATOM   9375  C CA  . LYS D 4 67  ? 114.837 127.783 131.451 1.00 146.03 ? 67  LYS H CA  1 
ATOM   9376  C C   . LYS D 4 67  ? 115.572 127.473 132.777 1.00 135.70 ? 67  LYS H C   1 
ATOM   9377  O O   . LYS D 4 67  ? 116.452 128.245 133.179 1.00 191.64 ? 67  LYS H O   1 
ATOM   9378  C CB  . LYS D 4 67  ? 113.525 128.523 131.738 1.00 150.27 ? 67  LYS H CB  1 
ATOM   9379  C CG  . LYS D 4 67  ? 113.669 129.841 132.512 1.00 209.10 ? 67  LYS H CG  1 
ATOM   9380  C CD  . LYS D 4 67  ? 112.395 130.599 132.860 1.00 272.51 ? 67  LYS H CD  1 
ATOM   9381  C CE  . LYS D 4 67  ? 111.680 131.197 131.664 1.00 338.40 ? 67  LYS H CE  1 
ATOM   9382  N NZ  . LYS D 4 67  ? 110.790 130.239 130.954 1.00 389.39 ? 67  LYS H NZ  1 
ATOM   9383  N N   . ALA D 4 68  ? 115.213 126.373 133.450 1.00 145.52 ? 68  ALA H N   1 
ATOM   9384  C CA  . ALA D 4 68  ? 115.879 125.877 134.644 1.00 121.66 ? 68  ALA H CA  1 
ATOM   9385  C C   . ALA D 4 68  ? 116.873 124.778 134.342 1.00 100.91 ? 68  ALA H C   1 
ATOM   9386  O O   . ALA D 4 68  ? 116.903 124.286 133.211 1.00 173.14 ? 68  ALA H O   1 
ATOM   9387  C CB  . ALA D 4 68  ? 114.839 125.282 135.518 1.00 136.19 ? 68  ALA H CB  1 
ATOM   9388  N N   . THR D 4 69  ? 117.631 124.418 135.376 1.00 84.60  ? 69  THR H N   1 
ATOM   9389  C CA  . THR D 4 69  ? 118.514 123.258 135.400 1.00 114.86 ? 69  THR H CA  1 
ATOM   9390  C C   . THR D 4 69  ? 118.966 122.948 136.833 1.00 111.18 ? 69  THR H C   1 
ATOM   9391  O O   . THR D 4 69  ? 119.718 123.729 137.461 1.00 147.75 ? 69  THR H O   1 
ATOM   9392  C CB  . THR D 4 69  ? 119.751 123.398 134.511 1.00 174.06 ? 69  THR H CB  1 
ATOM   9393  O OG1 . THR D 4 69  ? 119.360 123.359 133.135 1.00 240.19 ? 69  THR H OG1 1 
ATOM   9394  C CG2 . THR D 4 69  ? 120.769 122.299 134.743 1.00 151.44 ? 69  THR H CG2 1 
ATOM   9395  N N   . LEU D 4 70  ? 118.461 121.806 137.322 1.00 110.57 ? 70  LEU H N   1 
ATOM   9396  C CA  . LEU D 4 70  ? 118.733 121.317 138.662 1.00 114.49 ? 70  LEU H CA  1 
ATOM   9397  C C   . LEU D 4 70  ? 119.948 120.448 138.570 1.00 94.08  ? 70  LEU H C   1 
ATOM   9398  O O   . LEU D 4 70  ? 120.070 119.645 137.652 1.00 149.35 ? 70  LEU H O   1 
ATOM   9399  C CB  . LEU D 4 70  ? 117.568 120.484 139.220 1.00 83.57  ? 70  LEU H CB  1 
ATOM   9400  C CG  . LEU D 4 70  ? 116.514 121.249 140.015 1.00 80.32  ? 70  LEU H CG  1 
ATOM   9401  C CD1 . LEU D 4 70  ? 116.348 122.644 139.504 1.00 94.51  ? 70  LEU H CD1 1 
ATOM   9402  C CD2 . LEU D 4 70  ? 115.159 120.541 139.967 1.00 83.78  ? 70  LEU H CD2 1 
ATOM   9403  N N   . THR D 4 71  ? 120.803 120.590 139.564 1.00 83.56  ? 71  THR H N   1 
ATOM   9404  C CA  . THR D 4 71  ? 121.816 119.591 139.819 1.00 95.14  ? 71  THR H CA  1 
ATOM   9405  C C   . THR D 4 71  ? 121.823 119.377 141.307 1.00 94.66  ? 71  THR H C   1 
ATOM   9406  O O   . THR D 4 71  ? 120.906 119.891 142.006 1.00 86.27  ? 71  THR H O   1 
ATOM   9407  C CB  . THR D 4 71  ? 123.175 120.002 139.249 1.00 154.55 ? 71  THR H CB  1 
ATOM   9408  O OG1 . THR D 4 71  ? 123.647 121.186 139.886 1.00 141.41 ? 71  THR H OG1 1 
ATOM   9409  C CG2 . THR D 4 71  ? 123.112 120.284 137.764 1.00 291.56 ? 71  THR H CG2 1 
ATOM   9410  N N   . VAL D 4 72  ? 122.864 118.625 141.707 1.00 91.78  ? 72  VAL H N   1 
ATOM   9411  C CA  . VAL D 4 72  ? 122.970 118.092 143.042 1.00 96.47  ? 72  VAL H CA  1 
ATOM   9412  C C   . VAL D 4 72  ? 124.429 117.678 143.279 1.00 108.12 ? 72  VAL H C   1 
ATOM   9413  O O   . VAL D 4 72  ? 125.179 117.433 142.338 1.00 166.95 ? 72  VAL H O   1 
ATOM   9414  C CB  . VAL D 4 72  ? 121.919 116.967 143.168 1.00 89.52  ? 72  VAL H CB  1 
ATOM   9415  C CG1 . VAL D 4 72  ? 122.350 115.712 142.436 1.00 141.14 ? 72  VAL H CG1 1 
ATOM   9416  C CG2 . VAL D 4 72  ? 121.598 116.666 144.591 1.00 89.40  ? 72  VAL H CG2 1 
ATOM   9417  N N   . ASP D 4 73  ? 124.810 117.620 144.551 1.00 115.19 ? 73  ASP H N   1 
ATOM   9418  C CA  . ASP D 4 73  ? 126.139 117.246 145.008 1.00 150.83 ? 73  ASP H CA  1 
ATOM   9419  C C   . ASP D 4 73  ? 125.959 116.373 146.255 1.00 149.39 ? 73  ASP H C   1 
ATOM   9420  O O   . ASP D 4 73  ? 125.745 116.884 147.372 1.00 157.37 ? 73  ASP H O   1 
ATOM   9421  C CB  . ASP D 4 73  ? 127.017 118.479 145.284 1.00 199.08 ? 73  ASP H CB  1 
ATOM   9422  C CG  . ASP D 4 73  ? 128.195 118.236 146.217 1.00 245.29 ? 73  ASP H CG  1 
ATOM   9423  O OD1 . ASP D 4 73  ? 128.721 117.103 146.206 1.00 295.41 ? 73  ASP H OD1 1 
ATOM   9424  O OD2 . ASP D 4 73  ? 128.573 119.186 146.956 1.00 174.32 ? 73  ASP H OD2 1 
ATOM   9425  N N   . GLN D 4 74  ? 126.070 115.053 146.054 1.00 139.79 ? 74  GLN H N   1 
ATOM   9426  C CA  . GLN D 4 74  ? 125.882 114.102 147.140 1.00 159.55 ? 74  GLN H CA  1 
ATOM   9427  C C   . GLN D 4 74  ? 126.967 114.197 148.215 1.00 212.67 ? 74  GLN H C   1 
ATOM   9428  O O   . GLN D 4 74  ? 126.745 113.689 149.311 1.00 223.80 ? 74  GLN H O   1 
ATOM   9429  C CB  . GLN D 4 74  ? 125.881 112.675 146.595 1.00 167.45 ? 74  GLN H CB  1 
ATOM   9430  C CG  . GLN D 4 74  ? 124.707 112.418 145.677 1.00 221.02 ? 74  GLN H CG  1 
ATOM   9431  C CD  . GLN D 4 74  ? 125.024 111.468 144.556 1.00 288.41 ? 74  GLN H CD  1 
ATOM   9432  O OE1 . GLN D 4 74  ? 125.320 111.878 143.431 1.00 330.18 ? 74  GLN H OE1 1 
ATOM   9433  N NE2 . GLN D 4 74  ? 124.954 110.183 144.870 1.00 264.48 ? 74  GLN H NE2 1 
ATOM   9434  N N   . SER D 4 75  ? 128.130 114.810 147.917 1.00 220.65 ? 75  SER H N   1 
ATOM   9435  C CA  . SER D 4 75  ? 129.229 114.885 148.872 1.00 212.94 ? 75  SER H CA  1 
ATOM   9436  C C   . SER D 4 75  ? 128.936 115.867 150.007 1.00 211.41 ? 75  SER H C   1 
ATOM   9437  O O   . SER D 4 75  ? 129.552 115.751 151.071 1.00 232.36 ? 75  SER H O   1 
ATOM   9438  C CB  . SER D 4 75  ? 130.538 115.209 148.183 1.00 221.66 ? 75  SER H CB  1 
ATOM   9439  O OG  . SER D 4 75  ? 130.641 116.591 147.860 1.00 209.87 ? 75  SER H OG  1 
ATOM   9440  N N   . SER D 4 76  ? 128.003 116.816 149.788 1.00 202.37 ? 76  SER H N   1 
ATOM   9441  C CA  . SER D 4 76  ? 127.703 117.851 150.768 1.00 194.87 ? 76  SER H CA  1 
ATOM   9442  C C   . SER D 4 76  ? 126.213 117.927 151.133 1.00 148.91 ? 76  SER H C   1 
ATOM   9443  O O   . SER D 4 76  ? 125.835 118.792 151.916 1.00 159.82 ? 76  SER H O   1 
ATOM   9444  C CB  . SER D 4 76  ? 128.229 119.171 150.251 1.00 184.15 ? 76  SER H CB  1 
ATOM   9445  O OG  . SER D 4 76  ? 127.450 119.643 149.168 1.00 176.38 ? 76  SER H OG  1 
ATOM   9446  N N   . ASN D 4 77  ? 125.388 117.030 150.587 1.00 116.83 ? 77  ASN H N   1 
ATOM   9447  C CA  . ASN D 4 77  ? 123.954 117.112 150.698 1.00 109.71 ? 77  ASN H CA  1 
ATOM   9448  C C   . ASN D 4 77  ? 123.439 118.440 150.144 1.00 91.25  ? 77  ASN H C   1 
ATOM   9449  O O   . ASN D 4 77  ? 122.492 119.009 150.697 1.00 135.42 ? 77  ASN H O   1 
ATOM   9450  C CB  . ASN D 4 77  ? 123.470 116.901 152.135 1.00 139.10 ? 77  ASN H CB  1 
ATOM   9451  C CG  . ASN D 4 77  ? 124.007 115.667 152.824 1.00 203.91 ? 77  ASN H CG  1 
ATOM   9452  O OD1 . ASN D 4 77  ? 124.455 114.703 152.191 1.00 112.30 ? 77  ASN H OD1 1 
ATOM   9453  N ND2 . ASN D 4 77  ? 123.928 115.698 154.149 1.00 300.91 ? 77  ASN H ND2 1 
ATOM   9454  N N   . THR D 4 78  ? 124.004 118.924 149.046 1.00 74.94  ? 78  THR H N   1 
ATOM   9455  C CA  . THR D 4 78  ? 123.511 120.165 148.480 1.00 101.15 ? 78  THR H CA  1 
ATOM   9456  C C   . THR D 4 78  ? 122.806 119.935 147.149 1.00 84.64  ? 78  THR H C   1 
ATOM   9457  O O   . THR D 4 78  ? 123.272 119.162 146.335 1.00 118.99 ? 78  THR H O   1 
ATOM   9458  C CB  . THR D 4 78  ? 124.632 121.185 148.269 1.00 135.91 ? 78  THR H CB  1 
ATOM   9459  O OG1 . THR D 4 78  ? 125.354 121.418 149.482 1.00 173.63 ? 78  THR H OG1 1 
ATOM   9460  C CG2 . THR D 4 78  ? 124.140 122.525 147.754 1.00 145.33 ? 78  THR H CG2 1 
ATOM   9461  N N   . ALA D 4 79  ? 121.694 120.630 146.970 1.00 83.18  ? 79  ALA H N   1 
ATOM   9462  C CA  . ALA D 4 79  ? 120.985 120.737 145.730 1.00 88.19  ? 79  ALA H CA  1 
ATOM   9463  C C   . ALA D 4 79  ? 121.082 122.163 145.180 1.00 81.30  ? 79  ALA H C   1 
ATOM   9464  O O   . ALA D 4 79  ? 121.033 123.129 145.906 1.00 86.83  ? 79  ALA H O   1 
ATOM   9465  C CB  . ALA D 4 79  ? 119.579 120.317 146.088 1.00 123.69 ? 79  ALA H CB  1 
ATOM   9466  N N   . TYR D 4 80  ? 121.187 122.329 143.870 1.00 89.70  ? 80  TYR H N   1 
ATOM   9467  C CA  . TYR D 4 80  ? 121.420 123.623 143.244 1.00 92.52  ? 80  TYR H CA  1 
ATOM   9468  C C   . TYR D 4 80  ? 120.405 123.791 142.114 1.00 83.03  ? 80  TYR H C   1 
ATOM   9469  O O   . TYR D 4 80  ? 120.155 122.880 141.312 1.00 102.69 ? 80  TYR H O   1 
ATOM   9470  C CB  . TYR D 4 80  ? 122.811 123.703 142.604 1.00 136.10 ? 80  TYR H CB  1 
ATOM   9471  C CG  . TYR D 4 80  ? 124.009 123.494 143.507 1.00 115.28 ? 80  TYR H CG  1 
ATOM   9472  C CD1 . TYR D 4 80  ? 124.565 124.562 144.128 1.00 179.29 ? 80  TYR H CD1 1 
ATOM   9473  C CD2 . TYR D 4 80  ? 124.573 122.262 143.725 1.00 144.33 ? 80  TYR H CD2 1 
ATOM   9474  C CE1 . TYR D 4 80  ? 125.666 124.429 144.952 1.00 186.66 ? 80  TYR H CE1 1 
ATOM   9475  C CE2 . TYR D 4 80  ? 125.673 122.100 144.537 1.00 191.20 ? 80  TYR H CE2 1 
ATOM   9476  C CZ  . TYR D 4 80  ? 126.226 123.194 145.165 1.00 159.92 ? 80  TYR H CZ  1 
ATOM   9477  O OH  . TYR D 4 80  ? 127.321 123.081 145.985 1.00 231.79 ? 80  TYR H OH  1 
ATOM   9478  N N   . LEU D 4 81  ? 119.810 124.969 142.046 1.00 94.55  ? 81  LEU H N   1 
ATOM   9479  C CA  . LEU D 4 81  ? 118.974 125.345 140.920 1.00 77.59  ? 81  LEU H CA  1 
ATOM   9480  C C   . LEU D 4 81  ? 119.721 126.412 140.151 1.00 77.84  ? 81  LEU H C   1 
ATOM   9481  O O   . LEU D 4 81  ? 119.895 127.516 140.699 1.00 131.28 ? 81  LEU H O   1 
ATOM   9482  C CB  . LEU D 4 81  ? 117.623 125.834 141.472 1.00 70.67  ? 81  LEU H CB  1 
ATOM   9483  C CG  . LEU D 4 81  ? 116.772 126.698 140.546 1.00 86.91  ? 81  LEU H CG  1 
ATOM   9484  C CD1 . LEU D 4 81  ? 116.390 126.075 139.208 1.00 64.57  ? 81  LEU H CD1 1 
ATOM   9485  C CD2 . LEU D 4 81  ? 115.488 127.043 141.251 1.00 105.54 ? 81  LEU H CD2 1 
ATOM   9486  N N   . GLN D 4 82  ? 120.175 126.100 138.927 1.00 101.87 ? 82  GLN H N   1 
ATOM   9487  C CA  . GLN D 4 82  ? 120.493 127.160 137.957 1.00 133.00 ? 82  GLN H CA  1 
ATOM   9488  C C   . GLN D 4 82  ? 119.251 127.673 137.254 1.00 101.44 ? 82  GLN H C   1 
ATOM   9489  O O   . GLN D 4 82  ? 118.418 126.893 136.814 1.00 137.20 ? 82  GLN H O   1 
ATOM   9490  C CB  . GLN D 4 82  ? 121.307 126.783 136.717 1.00 157.62 ? 82  GLN H CB  1 
ATOM   9491  C CG  . GLN D 4 82  ? 122.732 126.384 137.029 1.00 234.77 ? 82  GLN H CG  1 
ATOM   9492  C CD  . GLN D 4 82  ? 123.642 126.689 135.861 1.00 277.79 ? 82  GLN H CD  1 
ATOM   9493  O OE1 . GLN D 4 82  ? 123.365 127.573 135.043 1.00 161.97 ? 82  GLN H OE1 1 
ATOM   9494  N NE2 . GLN D 4 82  ? 124.747 125.959 135.789 1.00 342.53 ? 82  GLN H NE2 1 
ATOM   9495  N N   . LEU D 4 83  ? 119.177 128.980 137.161 1.00 102.31 ? 83  LEU H N   1 
ATOM   9496  C CA  . LEU D 4 83  ? 118.151 129.640 136.390 1.00 116.96 ? 83  LEU H CA  1 
ATOM   9497  C C   . LEU D 4 83  ? 118.810 130.515 135.352 1.00 159.13 ? 83  LEU H C   1 
ATOM   9498  O O   . LEU D 4 83  ? 119.910 131.026 135.588 1.00 249.49 ? 83  LEU H O   1 
ATOM   9499  C CB  . LEU D 4 83  ? 117.336 130.489 137.343 1.00 143.46 ? 83  LEU H CB  1 
ATOM   9500  C CG  . LEU D 4 83  ? 115.980 129.921 137.690 1.00 161.74 ? 83  LEU H CG  1 
ATOM   9501  C CD1 . LEU D 4 83  ? 115.500 130.607 139.007 1.00 113.75 ? 83  LEU H CD1 1 
ATOM   9502  C CD2 . LEU D 4 83  ? 115.065 130.052 136.437 1.00 126.39 ? 83  LEU H CD2 1 
ATOM   9503  N N   . THR D 4 84  ? 118.140 130.667 134.196 1.00 162.95 ? 84  THR H N   1 
ATOM   9504  C CA  . THR D 4 84  ? 118.797 131.251 133.020 1.00 220.48 ? 84  THR H CA  1 
ATOM   9505  C C   . THR D 4 84  ? 117.831 132.171 132.276 1.00 186.75 ? 84  THR H C   1 
ATOM   9506  O O   . THR D 4 84  ? 116.619 131.999 132.399 1.00 226.12 ? 84  THR H O   1 
ATOM   9507  C CB  . THR D 4 84  ? 119.392 130.183 132.082 1.00 263.79 ? 84  THR H CB  1 
ATOM   9508  O OG1 . THR D 4 84  ? 118.313 129.514 131.441 1.00 266.55 ? 84  THR H OG1 1 
ATOM   9509  C CG2 . THR D 4 84  ? 120.262 129.158 132.773 1.00 307.50 ? 84  THR H CG2 1 
ATOM   9510  N N   . SER D 4 85  ? 118.389 133.134 131.521 1.00 175.59 ? 85  SER H N   1 
ATOM   9511  C CA  . SER D 4 85  ? 117.645 134.099 130.716 1.00 226.78 ? 85  SER H CA  1 
ATOM   9512  C C   . SER D 4 85  ? 116.690 134.995 131.543 1.00 225.72 ? 85  SER H C   1 
ATOM   9513  O O   . SER D 4 85  ? 115.638 135.446 131.044 1.00 227.47 ? 85  SER H O   1 
ATOM   9514  C CB  . SER D 4 85  ? 116.944 133.387 129.562 1.00 249.68 ? 85  SER H CB  1 
ATOM   9515  O OG  . SER D 4 85  ? 115.771 132.693 129.978 1.00 299.63 ? 85  SER H OG  1 
ATOM   9516  N N   . LEU D 4 86  ? 117.077 135.291 132.802 1.00 137.15 ? 86  LEU H N   1 
ATOM   9517  C CA  . LEU D 4 86  ? 116.214 135.989 133.752 1.00 140.33 ? 86  LEU H CA  1 
ATOM   9518  C C   . LEU D 4 86  ? 115.740 137.366 133.259 1.00 135.57 ? 86  LEU H C   1 
ATOM   9519  O O   . LEU D 4 86  ? 116.524 138.243 132.923 1.00 172.92 ? 86  LEU H O   1 
ATOM   9520  C CB  . LEU D 4 86  ? 116.951 136.118 135.094 1.00 128.95 ? 86  LEU H CB  1 
ATOM   9521  C CG  . LEU D 4 86  ? 116.890 134.852 135.936 1.00 158.07 ? 86  LEU H CG  1 
ATOM   9522  C CD1 . LEU D 4 86  ? 117.889 134.784 137.073 1.00 170.08 ? 86  LEU H CD1 1 
ATOM   9523  C CD2 . LEU D 4 86  ? 115.513 134.736 136.503 1.00 145.31 ? 86  LEU H CD2 1 
ATOM   9524  N N   . THR D 4 87  ? 114.418 137.536 133.260 1.00 132.11 ? 87  THR H N   1 
ATOM   9525  C CA  . THR D 4 87  ? 113.761 138.821 133.083 1.00 170.41 ? 87  THR H CA  1 
ATOM   9526  C C   . THR D 4 87  ? 113.402 139.424 134.451 1.00 136.06 ? 87  THR H C   1 
ATOM   9527  O O   . THR D 4 87  ? 113.489 138.765 135.482 1.00 127.28 ? 87  THR H O   1 
ATOM   9528  C CB  . THR D 4 87  ? 112.511 138.618 132.206 1.00 216.80 ? 87  THR H CB  1 
ATOM   9529  O OG1 . THR D 4 87  ? 111.547 137.873 132.942 1.00 166.63 ? 87  THR H OG1 1 
ATOM   9530  C CG2 . THR D 4 87  ? 112.782 137.848 130.929 1.00 279.43 ? 87  THR H CG2 1 
ATOM   9531  N N   . SER D 4 88  ? 112.942 140.673 134.442 1.00 171.98 ? 88  SER H N   1 
ATOM   9532  C CA  . SER D 4 88  ? 112.379 141.310 135.619 1.00 188.04 ? 88  SER H CA  1 
ATOM   9533  C C   . SER D 4 88  ? 111.204 140.503 136.168 1.00 175.82 ? 88  SER H C   1 
ATOM   9534  O O   . SER D 4 88  ? 111.097 140.365 137.380 1.00 203.26 ? 88  SER H O   1 
ATOM   9535  C CB  . SER D 4 88  ? 111.961 142.736 135.322 1.00 275.65 ? 88  SER H CB  1 
ATOM   9536  O OG  . SER D 4 88  ? 111.522 143.395 136.504 1.00 318.80 ? 88  SER H OG  1 
ATOM   9537  N N   . GLU D 4 89  ? 110.344 139.952 135.295 1.00 170.81 ? 89  GLU H N   1 
ATOM   9538  C CA  . GLU D 4 89  ? 109.196 139.161 135.743 1.00 209.61 ? 89  GLU H CA  1 
ATOM   9539  C C   . GLU D 4 89  ? 109.571 137.753 136.244 1.00 146.45 ? 89  GLU H C   1 
ATOM   9540  O O   . GLU D 4 89  ? 108.667 137.004 136.600 1.00 188.31 ? 89  GLU H O   1 
ATOM   9541  C CB  . GLU D 4 89  ? 108.120 139.080 134.650 1.00 276.22 ? 89  GLU H CB  1 
ATOM   9542  C CG  . GLU D 4 89  ? 108.505 138.279 133.412 1.00 318.98 ? 89  GLU H CG  1 
ATOM   9543  C CD  . GLU D 4 89  ? 107.368 137.808 132.523 1.00 444.73 ? 89  GLU H CD  1 
ATOM   9544  O OE1 . GLU D 4 89  ? 106.229 138.295 132.686 1.00 534.37 ? 89  GLU H OE1 1 
ATOM   9545  O OE2 . GLU D 4 89  ? 107.627 136.944 131.663 1.00 480.23 ? 89  GLU H OE2 1 
ATOM   9546  N N   . ASP D 4 90  ? 110.853 137.371 136.299 1.00 167.72 ? 90  ASP H N   1 
ATOM   9547  C CA  . ASP D 4 90  ? 111.327 136.184 137.017 1.00 120.36 ? 90  ASP H CA  1 
ATOM   9548  C C   . ASP D 4 90  ? 111.860 136.547 138.418 1.00 107.45 ? 90  ASP H C   1 
ATOM   9549  O O   . ASP D 4 90  ? 112.453 135.720 139.108 1.00 93.69  ? 90  ASP H O   1 
ATOM   9550  C CB  . ASP D 4 90  ? 112.372 135.478 136.136 1.00 136.74 ? 90  ASP H CB  1 
ATOM   9551  C CG  . ASP D 4 90  ? 111.884 135.003 134.767 1.00 192.32 ? 90  ASP H CG  1 
ATOM   9552  O OD1 . ASP D 4 90  ? 110.948 134.193 134.739 1.00 252.44 ? 90  ASP H OD1 1 
ATOM   9553  O OD2 . ASP D 4 90  ? 112.447 135.445 133.733 1.00 280.22 ? 90  ASP H OD2 1 
ATOM   9554  N N   . SER D 4 91  ? 111.678 137.805 138.854 1.00 107.67 ? 91  SER H N   1 
ATOM   9555  C CA  . SER D 4 91  ? 112.085 138.201 140.189 1.00 122.55 ? 91  SER H CA  1 
ATOM   9556  C C   . SER D 4 91  ? 111.086 137.595 141.131 1.00 136.62 ? 91  SER H C   1 
ATOM   9557  O O   . SER D 4 91  ? 109.904 137.705 140.829 1.00 160.24 ? 91  SER H O   1 
ATOM   9558  C CB  . SER D 4 91  ? 112.073 139.683 140.397 1.00 182.43 ? 91  SER H CB  1 
ATOM   9559  O OG  . SER D 4 91  ? 112.974 140.337 139.527 1.00 241.81 ? 91  SER H OG  1 
ATOM   9560  N N   . ALA D 4 92  ? 111.558 136.981 142.222 1.00 134.05 ? 92  ALA H N   1 
ATOM   9561  C CA  . ALA D 4 92  ? 110.692 136.177 143.076 1.00 113.90 ? 92  ALA H CA  1 
ATOM   9562  C C   . ALA D 4 92  ? 111.416 135.725 144.335 1.00 107.53 ? 92  ALA H C   1 
ATOM   9563  O O   . ALA D 4 92  ? 112.591 136.017 144.490 1.00 120.88 ? 92  ALA H O   1 
ATOM   9564  C CB  . ALA D 4 92  ? 110.269 134.954 142.294 1.00 99.23  ? 92  ALA H CB  1 
ATOM   9565  N N   . VAL D 4 93  ? 110.714 134.974 145.182 1.00 88.54  ? 93  VAL H N   1 
ATOM   9566  C CA  . VAL D 4 93  ? 111.368 134.081 146.117 1.00 84.63  ? 93  VAL H CA  1 
ATOM   9567  C C   . VAL D 4 93  ? 111.374 132.627 145.630 1.00 87.96  ? 93  VAL H C   1 
ATOM   9568  O O   . VAL D 4 93  ? 110.372 132.099 145.185 1.00 79.80  ? 93  VAL H O   1 
ATOM   9569  C CB  . VAL D 4 93  ? 110.625 134.074 147.421 1.00 80.00  ? 93  VAL H CB  1 
ATOM   9570  C CG1 . VAL D 4 93  ? 111.526 133.434 148.442 1.00 79.82  ? 93  VAL H CG1 1 
ATOM   9571  C CG2 . VAL D 4 93  ? 110.172 135.457 147.792 1.00 112.76 ? 93  VAL H CG2 1 
ATOM   9572  N N   . TYR D 4 94  ? 112.521 131.990 145.766 1.00 71.66  ? 94  TYR H N   1 
ATOM   9573  C CA  . TYR D 4 94  ? 112.750 130.637 145.324 1.00 72.91  ? 94  TYR H CA  1 
ATOM   9574  C C   . TYR D 4 94  ? 112.942 129.795 146.589 1.00 72.13  ? 94  TYR H C   1 
ATOM   9575  O O   . TYR D 4 94  ? 113.817 130.016 147.405 1.00 74.17  ? 94  TYR H O   1 
ATOM   9576  C CB  . TYR D 4 94  ? 113.954 130.623 144.351 1.00 63.28  ? 94  TYR H CB  1 
ATOM   9577  C CG  . TYR D 4 94  ? 113.570 131.271 143.029 1.00 50.48  ? 94  TYR H CG  1 
ATOM   9578  C CD1 . TYR D 4 94  ? 113.757 132.566 142.785 1.00 92.58  ? 94  TYR H CD1 1 
ATOM   9579  C CD2 . TYR D 4 94  ? 112.982 130.603 142.046 1.00 65.16  ? 94  TYR H CD2 1 
ATOM   9580  C CE1 . TYR D 4 94  ? 113.390 133.178 141.611 1.00 103.60 ? 94  TYR H CE1 1 
ATOM   9581  C CE2 . TYR D 4 94  ? 112.596 131.164 140.864 1.00 73.04  ? 94  TYR H CE2 1 
ATOM   9582  C CZ  . TYR D 4 94  ? 112.781 132.464 140.639 1.00 73.88  ? 94  TYR H CZ  1 
ATOM   9583  O OH  . TYR D 4 94  ? 112.373 132.960 139.461 1.00 94.92  ? 94  TYR H OH  1 
ATOM   9584  N N   . TYR D 4 95  ? 112.092 128.805 146.737 1.00 70.99  ? 95  TYR H N   1 
ATOM   9585  C CA  . TYR D 4 95  ? 112.114 127.918 147.862 1.00 64.89  ? 95  TYR H CA  1 
ATOM   9586  C C   . TYR D 4 95  ? 112.525 126.511 147.411 1.00 62.05  ? 95  TYR H C   1 
ATOM   9587  O O   . TYR D 4 95  ? 112.074 125.963 146.415 1.00 52.42  ? 95  TYR H O   1 
ATOM   9588  C CB  . TYR D 4 95  ? 110.688 127.844 148.400 1.00 65.65  ? 95  TYR H CB  1 
ATOM   9589  C CG  . TYR D 4 95  ? 110.095 129.049 149.103 1.00 54.45  ? 95  TYR H CG  1 
ATOM   9590  C CD1 . TYR D 4 95  ? 110.379 129.297 150.402 1.00 68.25  ? 95  TYR H CD1 1 
ATOM   9591  C CD2 . TYR D 4 95  ? 109.237 129.920 148.502 1.00 71.50  ? 95  TYR H CD2 1 
ATOM   9592  C CE1 . TYR D 4 95  ? 109.856 130.373 151.102 1.00 93.34  ? 95  TYR H CE1 1 
ATOM   9593  C CE2 . TYR D 4 95  ? 108.683 130.993 149.176 1.00 87.05  ? 95  TYR H CE2 1 
ATOM   9594  C CZ  . TYR D 4 95  ? 108.994 131.244 150.493 1.00 88.20  ? 95  TYR H CZ  1 
ATOM   9595  O OH  . TYR D 4 95  ? 108.521 132.307 151.223 1.00 118.06 ? 95  TYR H OH  1 
ATOM   9596  N N   . CYS D 4 96  ? 113.391 125.931 148.218 1.00 73.54  ? 96  CYS H N   1 
ATOM   9597  C CA  . CYS D 4 96  ? 113.806 124.552 148.165 1.00 67.76  ? 96  CYS H CA  1 
ATOM   9598  C C   . CYS D 4 96  ? 112.929 123.776 149.137 1.00 76.12  ? 96  CYS H C   1 
ATOM   9599  O O   . CYS D 4 96  ? 112.768 124.195 150.276 1.00 88.18  ? 96  CYS H O   1 
ATOM   9600  C CB  . CYS D 4 96  ? 115.221 124.521 148.683 1.00 78.47  ? 96  CYS H CB  1 
ATOM   9601  S SG  . CYS D 4 96  ? 115.965 122.896 148.719 1.00 149.65 ? 96  CYS H SG  1 
ATOM   9602  N N   . ALA D 4 97  ? 112.373 122.635 148.707 1.00 86.43  ? 97  ALA H N   1 
ATOM   9603  C CA  . ALA D 4 97  ? 111.393 121.844 149.462 1.00 69.58  ? 97  ALA H CA  1 
ATOM   9604  C C   . ALA D 4 97  ? 111.693 120.353 149.356 1.00 60.23  ? 97  ALA H C   1 
ATOM   9605  O O   . ALA D 4 97  ? 112.234 119.898 148.353 1.00 84.59  ? 97  ALA H O   1 
ATOM   9606  C CB  . ALA D 4 97  ? 110.009 122.102 148.908 1.00 83.23  ? 97  ALA H CB  1 
ATOM   9607  N N   . ARG D 4 98  ? 111.340 119.596 150.384 1.00 63.02  ? 98  ARG H N   1 
ATOM   9608  C CA  . ARG D 4 98  ? 111.516 118.151 150.422 1.00 68.27  ? 98  ARG H CA  1 
ATOM   9609  C C   . ARG D 4 98  ? 110.162 117.441 150.488 1.00 66.00  ? 98  ARG H C   1 
ATOM   9610  O O   . ARG D 4 98  ? 109.205 117.924 151.058 1.00 61.21  ? 98  ARG H O   1 
ATOM   9611  C CB  . ARG D 4 98  ? 112.342 117.741 151.642 1.00 59.17  ? 98  ARG H CB  1 
ATOM   9612  C CG  . ARG D 4 98  ? 113.176 116.513 151.416 1.00 66.75  ? 98  ARG H CG  1 
ATOM   9613  C CD  . ARG D 4 98  ? 113.442 115.653 152.613 1.00 69.33  ? 98  ARG H CD  1 
ATOM   9614  N NE  . ARG D 4 98  ? 112.305 114.858 152.942 1.00 55.51  ? 98  ARG H NE  1 
ATOM   9615  C CZ  . ARG D 4 98  ? 112.300 114.079 153.995 1.00 95.09  ? 98  ARG H CZ  1 
ATOM   9616  N NH1 . ARG D 4 98  ? 111.263 113.294 154.266 1.00 130.58 ? 98  ARG H NH1 1 
ATOM   9617  N NH2 . ARG D 4 98  ? 113.327 114.088 154.828 1.00 102.49 ? 98  ARG H NH2 1 
ATOM   9618  N N   . GLY D 4 99  ? 110.085 116.263 149.887 1.00 88.25  ? 99  GLY H N   1 
ATOM   9619  C CA  . GLY D 4 99  ? 108.867 115.479 149.948 1.00 100.89 ? 99  GLY H CA  1 
ATOM   9620  C C   . GLY D 4 99  ? 108.728 114.722 151.266 1.00 78.84  ? 99  GLY H C   1 
ATOM   9621  O O   . GLY D 4 99  ? 109.685 114.634 152.041 1.00 85.81  ? 99  GLY H O   1 
ATOM   9622  N N   . ARG D 4 100 ? 107.545 114.147 151.485 1.00 59.91  ? 100 ARG H N   1 
ATOM   9623  C CA  . ARG D 4 100 ? 107.410 113.182 152.564 1.00 73.71  ? 100 ARG H CA  1 
ATOM   9624  C C   . ARG D 4 100 ? 107.785 111.758 152.128 1.00 95.15  ? 100 ARG H C   1 
ATOM   9625  O O   . ARG D 4 100 ? 108.690 111.171 152.651 1.00 103.36 ? 100 ARG H O   1 
ATOM   9626  C CB  . ARG D 4 100 ? 105.994 113.269 153.154 1.00 110.39 ? 100 ARG H CB  1 
ATOM   9627  C CG  . ARG D 4 100 ? 105.823 112.485 154.451 1.00 116.65 ? 100 ARG H CG  1 
ATOM   9628  C CD  . ARG D 4 100 ? 107.024 112.791 155.399 1.00 135.04 ? 100 ARG H CD  1 
ATOM   9629  N NE  . ARG D 4 100 ? 106.674 112.866 156.793 1.00 146.89 ? 100 ARG H NE  1 
ATOM   9630  C CZ  . ARG D 4 100 ? 105.867 113.775 157.323 1.00 166.98 ? 100 ARG H CZ  1 
ATOM   9631  N NH1 . ARG D 4 100 ? 105.087 113.452 158.342 1.00 285.22 ? 100 ARG H NH1 1 
ATOM   9632  N NH2 . ARG D 4 100 ? 105.804 114.993 156.840 1.00 132.63 ? 100 ARG H NH2 1 
ATOM   9633  N N   . GLN D 4 101 ? 107.042 111.212 151.174 1.00 124.53 ? 101 GLN H N   1 
ATOM   9634  C CA  . GLN D 4 101 ? 107.321 109.992 150.441 1.00 100.59 ? 101 GLN H CA  1 
ATOM   9635  C C   . GLN D 4 101 ? 108.345 110.324 149.359 1.00 102.37 ? 101 GLN H C   1 
ATOM   9636  O O   . GLN D 4 101 ? 108.568 111.498 149.041 1.00 94.24  ? 101 GLN H O   1 
ATOM   9637  C CB  . GLN D 4 101 ? 106.019 109.522 149.745 1.00 141.64 ? 101 GLN H CB  1 
ATOM   9638  C CG  . GLN D 4 101 ? 105.252 108.381 150.416 1.00 111.82 ? 101 GLN H CG  1 
ATOM   9639  C CD  . GLN D 4 101 ? 105.903 107.095 149.981 1.00 235.75 ? 101 GLN H CD  1 
ATOM   9640  O OE1 . GLN D 4 101 ? 107.074 107.060 149.588 1.00 317.17 ? 101 GLN H OE1 1 
ATOM   9641  N NE2 . GLN D 4 101 ? 105.135 106.018 150.053 1.00 284.58 ? 101 GLN H NE2 1 
ATOM   9642  N N   . THR D 4 102 ? 108.933 109.289 148.735 1.00 124.45 ? 102 THR H N   1 
ATOM   9643  C CA  . THR D 4 102 ? 110.149 109.432 147.925 1.00 90.68  ? 102 THR H CA  1 
ATOM   9644  C C   . THR D 4 102 ? 109.794 109.985 146.581 1.00 60.38  ? 102 THR H C   1 
ATOM   9645  O O   . THR D 4 102 ? 109.446 109.165 145.762 1.00 92.19  ? 102 THR H O   1 
ATOM   9646  C CB  . THR D 4 102 ? 110.863 108.083 147.816 1.00 180.33 ? 102 THR H CB  1 
ATOM   9647  O OG1 . THR D 4 102 ? 111.428 107.847 149.113 1.00 331.19 ? 102 THR H OG1 1 
ATOM   9648  C CG2 . THR D 4 102 ? 112.000 108.042 146.822 1.00 280.22 ? 102 THR H CG2 1 
ATOM   9649  N N   . TYR D 4 103 ? 109.820 111.321 146.414 1.00 50.83  ? 103 TYR H N   1 
ATOM   9650  C CA  . TYR D 4 103 ? 109.376 112.101 145.217 1.00 65.93  ? 103 TYR H CA  1 
ATOM   9651  C C   . TYR D 4 103 ? 107.899 112.628 145.175 1.00 62.50  ? 103 TYR H C   1 
ATOM   9652  O O   . TYR D 4 103 ? 107.599 113.578 144.400 1.00 45.53  ? 103 TYR H O   1 
ATOM   9653  C CB  . TYR D 4 103 ? 109.622 111.594 143.758 1.00 47.54  ? 103 TYR H CB  1 
ATOM   9654  C CG  . TYR D 4 103 ? 108.588 110.838 142.957 1.00 47.43  ? 103 TYR H CG  1 
ATOM   9655  C CD1 . TYR D 4 103 ? 107.588 111.519 142.341 1.00 66.27  ? 103 TYR H CD1 1 
ATOM   9656  C CD2 . TYR D 4 103 ? 108.576 109.406 142.828 1.00 68.45  ? 103 TYR H CD2 1 
ATOM   9657  C CE1 . TYR D 4 103 ? 106.628 110.770 141.632 1.00 152.95 ? 103 TYR H CE1 1 
ATOM   9658  C CE2 . TYR D 4 103 ? 107.622 108.623 142.150 1.00 44.27  ? 103 TYR H CE2 1 
ATOM   9659  C CZ  . TYR D 4 103 ? 106.635 109.360 141.522 1.00 93.46  ? 103 TYR H CZ  1 
ATOM   9660  O OH  . TYR D 4 103 ? 105.570 108.924 140.771 1.00 96.50  ? 103 TYR H OH  1 
ATOM   9661  N N   . TYR D 4 104 ? 106.969 112.060 145.942 1.00 52.64  ? 104 TYR H N   1 
ATOM   9662  C CA  . TYR D 4 104 ? 105.606 112.531 145.808 1.00 63.78  ? 104 TYR H CA  1 
ATOM   9663  C C   . TYR D 4 104 ? 105.427 113.950 146.349 1.00 72.49  ? 104 TYR H C   1 
ATOM   9664  O O   . TYR D 4 104 ? 105.882 114.237 147.445 1.00 72.61  ? 104 TYR H O   1 
ATOM   9665  C CB  . TYR D 4 104 ? 104.603 111.631 146.523 1.00 77.78  ? 104 TYR H CB  1 
ATOM   9666  C CG  . TYR D 4 104 ? 104.431 110.231 145.956 1.00 63.42  ? 104 TYR H CG  1 
ATOM   9667  C CD1 . TYR D 4 104 ? 104.901 109.871 144.752 1.00 76.40  ? 104 TYR H CD1 1 
ATOM   9668  C CD2 . TYR D 4 104 ? 103.777 109.265 146.661 1.00 97.77  ? 104 TYR H CD2 1 
ATOM   9669  C CE1 . TYR D 4 104 ? 104.736 108.596 144.256 1.00 110.75 ? 104 TYR H CE1 1 
ATOM   9670  C CE2 . TYR D 4 104 ? 103.615 107.983 146.195 1.00 101.62 ? 104 TYR H CE2 1 
ATOM   9671  C CZ  . TYR D 4 104 ? 104.098 107.631 144.971 1.00 108.47 ? 104 TYR H CZ  1 
ATOM   9672  O OH  . TYR D 4 104 ? 103.989 106.384 144.433 1.00 159.47 ? 104 TYR H OH  1 
ATOM   9673  N N   . PRO D 4 105 ? 104.751 114.848 145.585 1.00 60.83  ? 105 PRO H N   1 
ATOM   9674  C CA  . PRO D 4 105 ? 104.774 116.282 145.845 1.00 56.45  ? 105 PRO H CA  1 
ATOM   9675  C C   . PRO D 4 105 ? 103.798 116.822 146.876 1.00 45.81  ? 105 PRO H C   1 
ATOM   9676  O O   . PRO D 4 105 ? 102.774 117.366 146.617 1.00 62.61  ? 105 PRO H O   1 
ATOM   9677  C CB  . PRO D 4 105 ? 104.504 116.765 144.407 1.00 68.88  ? 105 PRO H CB  1 
ATOM   9678  C CG  . PRO D 4 105 ? 103.468 115.820 143.838 1.00 59.55  ? 105 PRO H CG  1 
ATOM   9679  C CD  . PRO D 4 105 ? 103.958 114.524 144.395 1.00 59.20  ? 105 PRO H CD  1 
ATOM   9680  N N   . TRP D 4 106 ? 104.114 116.670 148.115 1.00 61.01  ? 106 TRP H N   1 
ATOM   9681  C CA  . TRP D 4 106 ? 103.571 117.562 149.128 1.00 71.72  ? 106 TRP H CA  1 
ATOM   9682  C C   . TRP D 4 106 ? 104.667 117.774 150.133 1.00 78.80  ? 106 TRP H C   1 
ATOM   9683  O O   . TRP D 4 106 ? 105.434 116.855 150.450 1.00 90.39  ? 106 TRP H O   1 
ATOM   9684  C CB  . TRP D 4 106 ? 102.354 117.017 149.890 1.00 71.34  ? 106 TRP H CB  1 
ATOM   9685  C CG  . TRP D 4 106 ? 102.525 115.793 150.751 1.00 78.89  ? 106 TRP H CG  1 
ATOM   9686  C CD1 . TRP D 4 106 ? 102.929 115.706 152.042 1.00 77.43  ? 106 TRP H CD1 1 
ATOM   9687  C CD2 . TRP D 4 106 ? 102.295 114.450 150.306 1.00 94.71  ? 106 TRP H CD2 1 
ATOM   9688  N NE1 . TRP D 4 106 ? 102.934 114.401 152.449 1.00 111.80 ? 106 TRP H NE1 1 
ATOM   9689  C CE2 . TRP D 4 106 ? 102.567 113.626 151.395 1.00 96.11  ? 106 TRP H CE2 1 
ATOM   9690  C CE3 . TRP D 4 106 ? 101.909 113.908 149.092 1.00 100.28 ? 106 TRP H CE3 1 
ATOM   9691  C CZ2 . TRP D 4 106 ? 102.451 112.268 151.312 1.00 92.13  ? 106 TRP H CZ2 1 
ATOM   9692  C CZ3 . TRP D 4 106 ? 101.832 112.564 148.995 1.00 128.88 ? 106 TRP H CZ3 1 
ATOM   9693  C CH2 . TRP D 4 106 ? 102.089 111.762 150.102 1.00 123.53 ? 106 TRP H CH2 1 
ATOM   9694  N N   . PHE D 4 107 ? 104.724 118.999 150.616 1.00 69.10  ? 107 PHE H N   1 
ATOM   9695  C CA  . PHE D 4 107 ? 105.994 119.540 151.020 1.00 63.67  ? 107 PHE H CA  1 
ATOM   9696  C C   . PHE D 4 107 ? 105.978 119.817 152.492 1.00 58.52  ? 107 PHE H C   1 
ATOM   9697  O O   . PHE D 4 107 ? 105.685 120.939 152.854 1.00 88.22  ? 107 PHE H O   1 
ATOM   9698  C CB  . PHE D 4 107 ? 106.316 120.783 150.172 1.00 64.49  ? 107 PHE H CB  1 
ATOM   9699  C CG  . PHE D 4 107 ? 106.238 120.497 148.707 1.00 51.18  ? 107 PHE H CG  1 
ATOM   9700  C CD1 . PHE D 4 107 ? 106.896 119.445 148.183 1.00 51.83  ? 107 PHE H CD1 1 
ATOM   9701  C CD2 . PHE D 4 107 ? 105.476 121.206 147.885 1.00 65.95  ? 107 PHE H CD2 1 
ATOM   9702  C CE1 . PHE D 4 107 ? 106.812 119.111 146.871 1.00 51.62  ? 107 PHE H CE1 1 
ATOM   9703  C CE2 . PHE D 4 107 ? 105.362 120.850 146.559 1.00 89.08  ? 107 PHE H CE2 1 
ATOM   9704  C CZ  . PHE D 4 107 ? 106.063 119.830 146.051 1.00 67.20  ? 107 PHE H CZ  1 
ATOM   9705  N N   . PRO D 4 108 ? 106.314 118.860 153.359 1.00 53.58  ? 108 PRO H N   1 
ATOM   9706  C CA  . PRO D 4 108 ? 106.441 119.165 154.758 1.00 70.86  ? 108 PRO H CA  1 
ATOM   9707  C C   . PRO D 4 108 ? 107.622 120.046 155.099 1.00 73.57  ? 108 PRO H C   1 
ATOM   9708  O O   . PRO D 4 108 ? 107.409 120.911 155.977 1.00 123.15 ? 108 PRO H O   1 
ATOM   9709  C CB  . PRO D 4 108 ? 106.627 117.832 155.381 1.00 86.54  ? 108 PRO H CB  1 
ATOM   9710  C CG  . PRO D 4 108 ? 107.343 117.131 154.343 1.00 87.11  ? 108 PRO H CG  1 
ATOM   9711  C CD  . PRO D 4 108 ? 106.616 117.486 153.079 1.00 54.95  ? 108 PRO H CD  1 
ATOM   9712  N N   . TYR D 4 109 ? 108.774 119.889 154.436 1.00 56.74  ? 109 TYR H N   1 
ATOM   9713  C CA  . TYR D 4 109 ? 109.917 120.678 154.854 1.00 86.68  ? 109 TYR H CA  1 
ATOM   9714  C C   . TYR D 4 109 ? 110.349 121.658 153.760 1.00 76.60  ? 109 TYR H C   1 
ATOM   9715  O O   . TYR D 4 109 ? 110.682 121.262 152.650 1.00 70.70  ? 109 TYR H O   1 
ATOM   9716  C CB  . TYR D 4 109 ? 111.022 119.722 155.276 1.00 101.74 ? 109 TYR H CB  1 
ATOM   9717  C CG  . TYR D 4 109 ? 110.603 118.570 156.174 1.00 84.67  ? 109 TYR H CG  1 
ATOM   9718  C CD1 . TYR D 4 109 ? 110.123 118.788 157.452 1.00 110.21 ? 109 TYR H CD1 1 
ATOM   9719  C CD2 . TYR D 4 109 ? 110.725 117.266 155.745 1.00 95.74  ? 109 TYR H CD2 1 
ATOM   9720  C CE1 . TYR D 4 109 ? 109.761 117.733 158.280 1.00 154.59 ? 109 TYR H CE1 1 
ATOM   9721  C CE2 . TYR D 4 109 ? 110.369 116.206 156.558 1.00 164.23 ? 109 TYR H CE2 1 
ATOM   9722  C CZ  . TYR D 4 109 ? 109.875 116.427 157.828 1.00 168.69 ? 109 TYR H CZ  1 
ATOM   9723  O OH  . TYR D 4 109 ? 109.549 115.298 158.532 1.00 178.34 ? 109 TYR H OH  1 
ATOM   9724  N N   . TRP D 4 110 ? 110.363 122.949 154.096 1.00 69.64  ? 110 TRP H N   1 
ATOM   9725  C CA  . TRP D 4 110 ? 110.864 123.969 153.192 1.00 67.02  ? 110 TRP H CA  1 
ATOM   9726  C C   . TRP D 4 110 ? 112.119 124.658 153.741 1.00 77.65  ? 110 TRP H C   1 
ATOM   9727  O O   . TRP D 4 110 ? 112.253 124.898 154.928 1.00 95.11  ? 110 TRP H O   1 
ATOM   9728  C CB  . TRP D 4 110 ? 109.791 125.036 153.007 1.00 65.06  ? 110 TRP H CB  1 
ATOM   9729  C CG  . TRP D 4 110 ? 108.486 124.597 152.449 1.00 54.62  ? 110 TRP H CG  1 
ATOM   9730  C CD1 . TRP D 4 110 ? 107.694 123.687 153.031 1.00 62.79  ? 110 TRP H CD1 1 
ATOM   9731  C CD2 . TRP D 4 110 ? 107.830 124.989 151.236 1.00 48.28  ? 110 TRP H CD2 1 
ATOM   9732  N NE1 . TRP D 4 110 ? 106.573 123.518 152.273 1.00 71.73  ? 110 TRP H NE1 1 
ATOM   9733  C CE2 . TRP D 4 110 ? 106.630 124.289 151.160 1.00 59.69  ? 110 TRP H CE2 1 
ATOM   9734  C CE3 . TRP D 4 110 ? 108.123 125.833 150.189 1.00 61.24  ? 110 TRP H CE3 1 
ATOM   9735  C CZ2 . TRP D 4 110 ? 105.717 124.396 150.117 1.00 76.85  ? 110 TRP H CZ2 1 
ATOM   9736  C CZ3 . TRP D 4 110 ? 107.246 125.937 149.123 1.00 85.14  ? 110 TRP H CZ3 1 
ATOM   9737  C CH2 . TRP D 4 110 ? 106.045 125.240 149.093 1.00 85.83  ? 110 TRP H CH2 1 
ATOM   9738  N N   . GLY D 4 111 ? 113.059 125.017 152.869 1.00 108.13 ? 111 GLY H N   1 
ATOM   9739  C CA  . GLY D 4 111 ? 114.075 125.986 153.243 1.00 124.11 ? 111 GLY H CA  1 
ATOM   9740  C C   . GLY D 4 111 ? 113.472 127.396 153.284 1.00 109.74 ? 111 GLY H C   1 
ATOM   9741  O O   . GLY D 4 111 ? 112.620 127.681 152.478 1.00 105.41 ? 111 GLY H O   1 
ATOM   9742  N N   . GLN D 4 112 ? 113.938 128.284 154.180 1.00 136.43 ? 112 GLN H N   1 
ATOM   9743  C CA  . GLN D 4 112 ? 113.640 129.717 154.160 1.00 120.42 ? 112 GLN H CA  1 
ATOM   9744  C C   . GLN D 4 112 ? 114.063 130.267 152.800 1.00 98.03  ? 112 GLN H C   1 
ATOM   9745  O O   . GLN D 4 112 ? 115.138 129.911 152.313 1.00 168.44 ? 112 GLN H O   1 
ATOM   9746  C CB  . GLN D 4 112 ? 114.412 130.437 155.261 1.00 153.58 ? 112 GLN H CB  1 
ATOM   9747  C CG  . GLN D 4 112 ? 114.355 129.793 156.649 1.00 239.03 ? 112 GLN H CG  1 
ATOM   9748  C CD  . GLN D 4 112 ? 112.990 129.711 157.308 1.00 362.61 ? 112 GLN H CD  1 
ATOM   9749  O OE1 . GLN D 4 112 ? 112.004 129.248 156.738 1.00 386.57 ? 112 GLN H OE1 1 
ATOM   9750  N NE2 . GLN D 4 112 ? 112.907 130.158 158.554 1.00 454.56 ? 112 GLN H NE2 1 
ATOM   9751  N N   . GLY D 4 113 ? 113.248 131.096 152.161 1.00 78.36  ? 113 GLY H N   1 
ATOM   9752  C CA  . GLY D 4 113 ? 113.413 131.317 150.718 1.00 99.64  ? 113 GLY H CA  1 
ATOM   9753  C C   . GLY D 4 113 ? 114.604 132.208 150.294 1.00 87.28  ? 113 GLY H C   1 
ATOM   9754  O O   . GLY D 4 113 ? 115.057 133.047 151.064 1.00 136.01 ? 113 GLY H O   1 
ATOM   9755  N N   . THR D 4 114 ? 115.098 132.042 149.065 1.00 96.77  ? 114 THR H N   1 
ATOM   9756  C CA  . THR D 4 114 ? 116.145 132.877 148.480 1.00 92.83  ? 114 THR H CA  1 
ATOM   9757  C C   . THR D 4 114 ? 115.490 133.955 147.654 1.00 73.89  ? 114 THR H C   1 
ATOM   9758  O O   . THR D 4 114 ? 114.822 133.639 146.691 1.00 74.05  ? 114 THR H O   1 
ATOM   9759  C CB  . THR D 4 114 ? 117.073 132.061 147.553 1.00 136.29 ? 114 THR H CB  1 
ATOM   9760  O OG1 . THR D 4 114 ? 117.711 130.989 148.263 1.00 132.72 ? 114 THR H OG1 1 
ATOM   9761  C CG2 . THR D 4 114 ? 118.140 132.913 146.914 1.00 131.87 ? 114 THR H CG2 1 
ATOM   9762  N N   . LEU D 4 115 ? 115.658 135.216 148.020 1.00 106.54 ? 115 LEU H N   1 
ATOM   9763  C CA  . LEU D 4 115 ? 114.968 136.278 147.307 1.00 114.37 ? 115 LEU H CA  1 
ATOM   9764  C C   . LEU D 4 115 ? 115.841 136.747 146.145 1.00 131.50 ? 115 LEU H C   1 
ATOM   9765  O O   . LEU D 4 115 ? 116.880 137.368 146.339 1.00 143.13 ? 115 LEU H O   1 
ATOM   9766  C CB  . LEU D 4 115 ? 114.649 137.408 148.278 1.00 100.52 ? 115 LEU H CB  1 
ATOM   9767  C CG  . LEU D 4 115 ? 113.490 138.272 147.827 1.00 130.10 ? 115 LEU H CG  1 
ATOM   9768  C CD1 . LEU D 4 115 ? 113.087 139.225 148.985 1.00 181.08 ? 115 LEU H CD1 1 
ATOM   9769  C CD2 . LEU D 4 115 ? 113.828 139.012 146.501 1.00 144.70 ? 115 LEU H CD2 1 
ATOM   9770  N N   . VAL D 4 116 ? 115.388 136.461 144.923 1.00 104.18 ? 116 VAL H N   1 
ATOM   9771  C CA  . VAL D 4 116 ? 116.129 136.748 143.701 1.00 94.32  ? 116 VAL H CA  1 
ATOM   9772  C C   . VAL D 4 116 ? 115.549 137.960 143.010 1.00 125.05 ? 116 VAL H C   1 
ATOM   9773  O O   . VAL D 4 116 ? 114.407 137.880 142.494 1.00 105.70 ? 116 VAL H O   1 
ATOM   9774  C CB  . VAL D 4 116 ? 116.030 135.557 142.760 1.00 113.47 ? 116 VAL H CB  1 
ATOM   9775  C CG1 . VAL D 4 116 ? 116.367 135.831 141.298 1.00 108.50 ? 116 VAL H CG1 1 
ATOM   9776  C CG2 . VAL D 4 116 ? 116.871 134.447 143.341 1.00 121.17 ? 116 VAL H CG2 1 
ATOM   9777  N N   . THR D 4 117 ? 116.374 139.039 142.991 1.00 137.18 ? 117 THR H N   1 
ATOM   9778  C CA  . THR D 4 117 ? 115.974 140.282 142.360 1.00 158.03 ? 117 THR H CA  1 
ATOM   9779  C C   . THR D 4 117 ? 116.699 140.446 141.030 1.00 136.14 ? 117 THR H C   1 
ATOM   9780  O O   . THR D 4 117 ? 117.910 140.311 140.999 1.00 85.06  ? 117 THR H O   1 
ATOM   9781  C CB  . THR D 4 117 ? 116.194 141.486 143.279 1.00 157.89 ? 117 THR H CB  1 
ATOM   9782  O OG1 . THR D 4 117 ? 115.923 141.224 144.659 1.00 156.96 ? 117 THR H OG1 1 
ATOM   9783  C CG2 . THR D 4 117 ? 115.263 142.591 142.838 1.00 188.68 ? 117 THR H CG2 1 
ATOM   9784  N N   . VAL D 4 118 ? 115.945 140.760 139.959 1.00 140.74 ? 118 VAL H N   1 
ATOM   9785  C CA  . VAL D 4 118 ? 116.523 140.937 138.632 1.00 146.77 ? 118 VAL H CA  1 
ATOM   9786  C C   . VAL D 4 118 ? 116.439 142.421 138.279 1.00 192.83 ? 118 VAL H C   1 
ATOM   9787  O O   . VAL D 4 118 ? 115.348 142.927 137.988 1.00 154.76 ? 118 VAL H O   1 
ATOM   9788  C CB  . VAL D 4 118 ? 115.830 140.069 137.570 1.00 141.96 ? 118 VAL H CB  1 
ATOM   9789  C CG1 . VAL D 4 118 ? 116.390 140.286 136.171 1.00 177.00 ? 118 VAL H CG1 1 
ATOM   9790  C CG2 . VAL D 4 118 ? 115.925 138.606 137.926 1.00 156.09 ? 118 VAL H CG2 1 
ATOM   9791  N N   . SER D 4 119 ? 117.607 143.098 138.302 1.00 193.04 ? 119 SER H N   1 
ATOM   9792  C CA  . SER D 4 119 ? 117.698 144.533 138.075 1.00 192.97 ? 119 SER H CA  1 
ATOM   9793  C C   . SER D 4 119 ? 119.123 144.915 137.710 1.00 205.71 ? 119 SER H C   1 
ATOM   9794  O O   . SER D 4 119 ? 120.066 144.286 138.187 1.00 195.66 ? 119 SER H O   1 
ATOM   9795  C CB  . SER D 4 119 ? 117.253 145.319 139.281 1.00 220.61 ? 119 SER H CB  1 
ATOM   9796  O OG  . SER D 4 119 ? 117.390 146.723 139.064 1.00 263.55 ? 119 SER H OG  1 
ATOM   9797  N N   . ALA D 4 120 ? 119.250 145.954 136.872 1.00 240.41 ? 120 ALA H N   1 
ATOM   9798  C CA  . ALA D 4 120 ? 120.540 146.479 136.451 1.00 281.24 ? 120 ALA H CA  1 
ATOM   9799  C C   . ALA D 4 120 ? 121.188 147.347 137.534 1.00 224.29 ? 120 ALA H C   1 
ATOM   9800  O O   . ALA D 4 120 ? 122.421 147.478 137.518 1.00 207.67 ? 120 ALA H O   1 
ATOM   9801  C CB  . ALA D 4 120 ? 120.355 147.249 135.166 1.00 346.27 ? 120 ALA H CB  1 
ATOM   9802  N N   . ALA D 4 121 ? 120.362 147.926 138.437 1.00 194.88 ? 121 ALA H N   1 
ATOM   9803  C CA  . ALA D 4 121 ? 120.807 148.802 139.512 1.00 215.40 ? 121 ALA H CA  1 
ATOM   9804  C C   . ALA D 4 121 ? 121.806 148.075 140.414 1.00 158.72 ? 121 ALA H C   1 
ATOM   9805  O O   . ALA D 4 121 ? 121.644 146.900 140.728 1.00 175.74 ? 121 ALA H O   1 
ATOM   9806  C CB  . ALA D 4 121 ? 119.623 149.340 140.309 1.00 249.06 ? 121 ALA H CB  1 
ATOM   9807  N N   . LYS D 4 122 ? 122.837 148.812 140.843 1.00 214.47 ? 122 LYS H N   1 
ATOM   9808  C CA  . LYS D 4 122 ? 123.964 148.234 141.556 1.00 234.44 ? 122 LYS H CA  1 
ATOM   9809  C C   . LYS D 4 122 ? 123.610 148.034 143.035 1.00 231.48 ? 122 LYS H C   1 
ATOM   9810  O O   . LYS D 4 122 ? 122.770 148.773 143.615 1.00 137.48 ? 122 LYS H O   1 
ATOM   9811  C CB  . LYS D 4 122 ? 125.224 149.097 141.402 1.00 293.20 ? 122 LYS H CB  1 
ATOM   9812  C CG  . LYS D 4 122 ? 125.163 150.517 141.959 1.00 359.28 ? 122 LYS H CG  1 
ATOM   9813  C CD  . LYS D 4 122 ? 126.503 151.208 141.950 1.00 427.49 ? 122 LYS H CD  1 
ATOM   9814  C CE  . LYS D 4 122 ? 126.451 152.586 142.572 1.00 502.71 ? 122 LYS H CE  1 
ATOM   9815  N NZ  . LYS D 4 122 ? 127.781 153.238 142.561 1.00 553.99 ? 122 LYS H NZ  1 
ATOM   9816  N N   . THR D 4 123 ? 124.285 147.006 143.609 1.00 222.48 ? 123 THR H N   1 
ATOM   9817  C CA  . THR D 4 123 ? 124.351 146.756 145.040 1.00 189.25 ? 123 THR H CA  1 
ATOM   9818  C C   . THR D 4 123 ? 124.724 148.042 145.756 1.00 198.79 ? 123 THR H C   1 
ATOM   9819  O O   . THR D 4 123 ? 125.648 148.731 145.315 1.00 275.12 ? 123 THR H O   1 
ATOM   9820  C CB  . THR D 4 123 ? 125.384 145.683 145.395 1.00 216.35 ? 123 THR H CB  1 
ATOM   9821  O OG1 . THR D 4 123 ? 125.126 144.506 144.624 1.00 281.99 ? 123 THR H OG1 1 
ATOM   9822  C CG2 . THR D 4 123 ? 125.361 145.364 146.875 1.00 209.58 ? 123 THR H CG2 1 
ATOM   9823  N N   . THR D 4 124 ? 123.989 148.358 146.830 1.00 183.10 ? 124 THR H N   1 
ATOM   9824  C CA  . THR D 4 124 ? 124.178 149.617 147.535 1.00 196.63 ? 124 THR H CA  1 
ATOM   9825  C C   . THR D 4 124 ? 123.998 149.344 149.021 1.00 193.60 ? 124 THR H C   1 
ATOM   9826  O O   . THR D 4 124 ? 122.869 149.154 149.471 1.00 290.00 ? 124 THR H O   1 
ATOM   9827  C CB  . THR D 4 124 ? 123.213 150.694 147.015 1.00 267.82 ? 124 THR H CB  1 
ATOM   9828  O OG1 . THR D 4 124 ? 123.347 150.880 145.602 1.00 292.68 ? 124 THR H OG1 1 
ATOM   9829  C CG2 . THR D 4 124 ? 123.455 152.029 147.688 1.00 271.34 ? 124 THR H CG2 1 
ATOM   9830  N N   . PRO D 4 125 ? 125.079 149.301 149.826 1.00 208.20 ? 125 PRO H N   1 
ATOM   9831  C CA  . PRO D 4 125 ? 124.934 149.102 151.265 1.00 219.33 ? 125 PRO H CA  1 
ATOM   9832  C C   . PRO D 4 125 ? 124.072 150.169 151.941 1.00 215.23 ? 125 PRO H C   1 
ATOM   9833  O O   . PRO D 4 125 ? 123.995 151.309 151.490 1.00 200.27 ? 125 PRO H O   1 
ATOM   9834  C CB  . PRO D 4 125 ? 126.375 149.169 151.792 1.00 272.92 ? 125 PRO H CB  1 
ATOM   9835  C CG  . PRO D 4 125 ? 127.214 148.800 150.602 1.00 320.52 ? 125 PRO H CG  1 
ATOM   9836  C CD  . PRO D 4 125 ? 126.488 149.411 149.422 1.00 283.76 ? 125 PRO H CD  1 
ATOM   9837  N N   . PRO D 4 126 ? 123.409 149.821 153.061 1.00 220.17 ? 126 PRO H N   1 
ATOM   9838  C CA  . PRO D 4 126 ? 122.488 150.740 153.722 1.00 199.08 ? 126 PRO H CA  1 
ATOM   9839  C C   . PRO D 4 126 ? 123.179 151.836 154.533 1.00 235.45 ? 126 PRO H C   1 
ATOM   9840  O O   . PRO D 4 126 ? 124.287 151.653 155.033 1.00 246.52 ? 126 PRO H O   1 
ATOM   9841  C CB  . PRO D 4 126 ? 121.703 149.808 154.661 1.00 229.93 ? 126 PRO H CB  1 
ATOM   9842  C CG  . PRO D 4 126 ? 122.672 148.689 154.995 1.00 241.62 ? 126 PRO H CG  1 
ATOM   9843  C CD  . PRO D 4 126 ? 123.523 148.530 153.758 1.00 245.80 ? 126 PRO H CD  1 
ATOM   9844  N N   . SER D 4 127 ? 122.486 152.976 154.645 1.00 251.30 ? 127 SER H N   1 
ATOM   9845  C CA  . SER D 4 127 ? 122.820 154.044 155.570 1.00 252.45 ? 127 SER H CA  1 
ATOM   9846  C C   . SER D 4 127 ? 121.777 154.064 156.689 1.00 224.94 ? 127 SER H C   1 
ATOM   9847  O O   . SER D 4 127 ? 120.575 154.167 156.414 1.00 224.00 ? 127 SER H O   1 
ATOM   9848  C CB  . SER D 4 127 ? 122.885 155.352 154.838 1.00 293.47 ? 127 SER H CB  1 
ATOM   9849  O OG  . SER D 4 127 ? 123.992 155.380 153.947 1.00 307.29 ? 127 SER H OG  1 
ATOM   9850  N N   . ASP D 4 128 ? 122.249 153.962 157.946 1.00 220.69 ? 128 ASP H N   1 
ATOM   9851  C CA  . ASP D 4 128 ? 121.398 153.766 159.117 1.00 219.11 ? 128 ASP H CA  1 
ATOM   9852  C C   . ASP D 4 128 ? 121.408 155.029 159.966 1.00 217.14 ? 128 ASP H C   1 
ATOM   9853  O O   . ASP D 4 128 ? 122.464 155.610 160.221 1.00 249.60 ? 128 ASP H O   1 
ATOM   9854  C CB  . ASP D 4 128 ? 121.839 152.589 159.986 1.00 194.68 ? 128 ASP H CB  1 
ATOM   9855  C CG  . ASP D 4 128 ? 122.357 151.453 159.133 1.00 212.55 ? 128 ASP H CG  1 
ATOM   9856  O OD1 . ASP D 4 128 ? 121.597 151.016 158.261 1.00 199.29 ? 128 ASP H OD1 1 
ATOM   9857  O OD2 . ASP D 4 128 ? 123.513 151.036 159.344 1.00 302.13 ? 128 ASP H OD2 1 
ATOM   9858  N N   . TYR D 4 129 ? 120.218 155.434 160.397 1.00 202.95 ? 129 TYR H N   1 
ATOM   9859  C CA  . TYR D 4 129 ? 120.052 156.700 161.079 1.00 210.40 ? 129 TYR H CA  1 
ATOM   9860  C C   . TYR D 4 129 ? 119.111 156.446 162.244 1.00 191.16 ? 129 TYR H C   1 
ATOM   9861  O O   . TYR D 4 129 ? 117.935 156.155 162.040 1.00 216.69 ? 129 TYR H O   1 
ATOM   9862  C CB  . TYR D 4 129 ? 119.568 157.751 160.075 1.00 229.26 ? 129 TYR H CB  1 
ATOM   9863  C CG  . TYR D 4 129 ? 120.568 158.113 158.989 1.00 211.83 ? 129 TYR H CG  1 
ATOM   9864  C CD1 . TYR D 4 129 ? 121.822 158.603 159.323 1.00 256.77 ? 129 TYR H CD1 1 
ATOM   9865  C CD2 . TYR D 4 129 ? 120.265 157.961 157.632 1.00 204.93 ? 129 TYR H CD2 1 
ATOM   9866  C CE1 . TYR D 4 129 ? 122.746 158.935 158.341 1.00 333.42 ? 129 TYR H CE1 1 
ATOM   9867  C CE2 . TYR D 4 129 ? 121.177 158.291 156.639 1.00 222.47 ? 129 TYR H CE2 1 
ATOM   9868  C CZ  . TYR D 4 129 ? 122.424 158.781 156.998 1.00 328.22 ? 129 TYR H CZ  1 
ATOM   9869  O OH  . TYR D 4 129 ? 123.343 159.116 156.042 1.00 378.22 ? 129 TYR H OH  1 
ATOM   9870  N N   . PRO D 4 130 ? 119.594 156.544 163.497 1.00 203.39 ? 130 PRO H N   1 
ATOM   9871  C CA  . PRO D 4 130 ? 118.744 156.310 164.659 1.00 217.28 ? 130 PRO H CA  1 
ATOM   9872  C C   . PRO D 4 130 ? 117.802 157.480 164.923 1.00 173.60 ? 130 PRO H C   1 
ATOM   9873  O O   . PRO D 4 130 ? 118.115 158.616 164.572 1.00 228.41 ? 130 PRO H O   1 
ATOM   9874  C CB  . PRO D 4 130 ? 119.768 156.126 165.790 1.00 258.99 ? 130 PRO H CB  1 
ATOM   9875  C CG  . PRO D 4 130 ? 120.940 156.982 165.377 1.00 290.69 ? 130 PRO H CG  1 
ATOM   9876  C CD  . PRO D 4 130 ? 120.972 156.889 163.870 1.00 260.92 ? 130 PRO H CD  1 
ATOM   9877  N N   . LEU D 4 131 ? 116.661 157.170 165.556 1.00 171.62 ? 131 LEU H N   1 
ATOM   9878  C CA  . LEU D 4 131 ? 115.608 158.124 165.847 1.00 219.70 ? 131 LEU H CA  1 
ATOM   9879  C C   . LEU D 4 131 ? 115.352 158.142 167.359 1.00 253.38 ? 131 LEU H C   1 
ATOM   9880  O O   . LEU D 4 131 ? 115.077 157.093 167.951 1.00 211.74 ? 131 LEU H O   1 
ATOM   9881  C CB  . LEU D 4 131 ? 114.365 157.700 165.056 1.00 208.91 ? 131 LEU H CB  1 
ATOM   9882  C CG  . LEU D 4 131 ? 114.505 157.597 163.534 1.00 176.72 ? 131 LEU H CG  1 
ATOM   9883  C CD1 . LEU D 4 131 ? 113.211 157.122 162.911 1.00 183.01 ? 131 LEU H CD1 1 
ATOM   9884  C CD2 . LEU D 4 131 ? 114.878 158.916 162.894 1.00 253.54 ? 131 LEU H CD2 1 
ATOM   9885  N N   . ALA D 4 132 ? 115.458 159.339 167.971 1.00 250.81 ? 132 ALA H N   1 
ATOM   9886  C CA  . ALA D 4 132 ? 115.135 159.533 169.379 1.00 269.66 ? 132 ALA H CA  1 
ATOM   9887  C C   . ALA D 4 132 ? 114.136 160.686 169.530 1.00 268.36 ? 132 ALA H C   1 
ATOM   9888  O O   . ALA D 4 132 ? 114.183 161.639 168.745 1.00 171.18 ? 132 ALA H O   1 
ATOM   9889  C CB  . ALA D 4 132 ? 116.394 159.763 170.174 1.00 302.86 ? 132 ALA H CB  1 
ATOM   9890  N N   . PRO D 4 133 ? 113.204 160.628 170.525 1.00 298.43 ? 133 PRO H N   1 
ATOM   9891  C CA  . PRO D 4 133 ? 112.028 161.516 170.549 1.00 310.89 ? 133 PRO H CA  1 
ATOM   9892  C C   . PRO D 4 133 ? 112.238 163.033 170.647 1.00 295.58 ? 133 PRO H C   1 
ATOM   9893  O O   . PRO D 4 133 ? 111.377 163.780 170.186 1.00 286.36 ? 133 PRO H O   1 
ATOM   9894  C CB  . PRO D 4 133 ? 111.264 161.060 171.813 1.00 329.10 ? 133 PRO H CB  1 
ATOM   9895  C CG  . PRO D 4 133 ? 111.738 159.643 172.054 1.00 328.03 ? 133 PRO H CG  1 
ATOM   9896  C CD  . PRO D 4 133 ? 113.200 159.698 171.678 1.00 275.98 ? 133 PRO H CD  1 
ATOM   9897  N N   . GLY D 4 134 ? 113.356 163.482 171.244 1.00 369.46 ? 134 GLY H N   1 
ATOM   9898  C CA  . GLY D 4 134 ? 113.653 164.902 171.413 1.00 424.93 ? 134 GLY H CA  1 
ATOM   9899  C C   . GLY D 4 134 ? 112.886 165.532 172.583 1.00 455.11 ? 134 GLY H C   1 
ATOM   9900  O O   . GLY D 4 134 ? 113.043 165.097 173.724 1.00 388.42 ? 134 GLY H O   1 
ATOM   9901  N N   . SER D 4 135 ? 112.062 166.560 172.291 1.00 514.35 ? 135 SER H N   1 
ATOM   9902  C CA  . SER D 4 135 ? 111.322 167.320 173.295 1.00 530.91 ? 135 SER H CA  1 
ATOM   9903  C C   . SER D 4 135 ? 110.262 166.456 173.988 1.00 532.19 ? 135 SER H C   1 
ATOM   9904  O O   . SER D 4 135 ? 109.605 165.647 173.333 1.00 570.32 ? 135 SER H O   1 
ATOM   9905  C CB  . SER D 4 135 ? 110.683 168.549 172.679 1.00 534.29 ? 135 SER H CB  1 
ATOM   9906  O OG  . SER D 4 135 ? 111.661 169.427 172.138 1.00 500.96 ? 135 SER H OG  1 
ATOM   9907  N N   . ALA D 4 136 ? 110.116 166.644 175.316 1.00 512.20 ? 136 ALA H N   1 
ATOM   9908  C CA  . ALA D 4 136 ? 109.078 166.041 176.156 1.00 531.99 ? 136 ALA H CA  1 
ATOM   9909  C C   . ALA D 4 136 ? 109.101 164.505 176.129 1.00 536.44 ? 136 ALA H C   1 
ATOM   9910  O O   . ALA D 4 136 ? 108.059 163.866 176.316 1.00 513.04 ? 136 ALA H O   1 
ATOM   9911  C CB  . ALA D 4 136 ? 107.720 166.593 175.762 1.00 543.15 ? 136 ALA H CB  1 
ATOM   9912  N N   . ALA D 4 137 ? 110.296 163.919 175.926 1.00 559.29 ? 137 ALA H N   1 
ATOM   9913  C CA  . ALA D 4 137 ? 110.461 162.484 175.721 1.00 590.27 ? 137 ALA H CA  1 
ATOM   9914  C C   . ALA D 4 137 ? 110.018 161.693 176.953 1.00 596.15 ? 137 ALA H C   1 
ATOM   9915  O O   . ALA D 4 137 ? 109.220 160.765 176.829 1.00 584.60 ? 137 ALA H O   1 
ATOM   9916  C CB  . ALA D 4 137 ? 111.901 162.179 175.380 1.00 596.50 ? 137 ALA H CB  1 
ATOM   9917  N N   . GLN D 4 138 ? 110.535 162.082 178.132 1.00 598.31 ? 138 GLN H N   1 
ATOM   9918  C CA  . GLN D 4 138 ? 110.334 161.349 179.380 1.00 602.69 ? 138 GLN H CA  1 
ATOM   9919  C C   . GLN D 4 138 ? 109.030 161.743 180.092 1.00 592.08 ? 138 GLN H C   1 
ATOM   9920  O O   . GLN D 4 138 ? 108.779 161.248 181.191 1.00 586.58 ? 138 GLN H O   1 
ATOM   9921  C CB  . GLN D 4 138 ? 111.545 161.560 180.301 1.00 606.99 ? 138 GLN H CB  1 
ATOM   9922  C CG  . GLN D 4 138 ? 112.849 160.974 179.765 1.00 606.18 ? 138 GLN H CG  1 
ATOM   9923  C CD  . GLN D 4 138 ? 112.884 159.465 179.827 1.00 606.54 ? 138 GLN H CD  1 
ATOM   9924  O OE1 . GLN D 4 138 ? 112.530 158.780 178.868 1.00 632.48 ? 138 GLN H OE1 1 
ATOM   9925  N NE2 . GLN D 4 138 ? 113.304 158.930 180.963 1.00 583.99 ? 138 GLN H NE2 1 
ATOM   9926  N N   . THR D 4 139 ? 108.192 162.603 179.481 1.00 588.27 ? 139 THR H N   1 
ATOM   9927  C CA  . THR D 4 139 ? 106.895 162.995 180.032 1.00 583.04 ? 139 THR H CA  1 
ATOM   9928  C C   . THR D 4 139 ? 105.878 161.838 180.008 1.00 547.85 ? 139 THR H C   1 
ATOM   9929  O O   . THR D 4 139 ? 104.832 161.949 180.649 1.00 555.06 ? 139 THR H O   1 
ATOM   9930  C CB  . THR D 4 139 ? 106.371 164.248 179.303 1.00 597.72 ? 139 THR H CB  1 
ATOM   9931  O OG1 . THR D 4 139 ? 107.397 165.242 179.288 1.00 609.80 ? 139 THR H OG1 1 
ATOM   9932  C CG2 . THR D 4 139 ? 105.134 164.855 179.934 1.00 598.48 ? 139 THR H CG2 1 
ATOM   9933  N N   . ASN D 4 140 ? 106.163 160.735 179.284 1.00 486.52 ? 140 ASN H N   1 
ATOM   9934  C CA  . ASN D 4 140 ? 105.292 159.566 179.208 1.00 438.67 ? 140 ASN H CA  1 
ATOM   9935  C C   . ASN D 4 140 ? 106.026 158.315 179.705 1.00 392.16 ? 140 ASN H C   1 
ATOM   9936  O O   . ASN D 4 140 ? 107.252 158.228 179.635 1.00 383.24 ? 140 ASN H O   1 
ATOM   9937  C CB  . ASN D 4 140 ? 104.766 159.371 177.780 1.00 449.58 ? 140 ASN H CB  1 
ATOM   9938  C CG  . ASN D 4 140 ? 103.969 160.533 177.214 1.00 482.83 ? 140 ASN H CG  1 
ATOM   9939  O OD1 . ASN D 4 140 ? 103.862 160.669 175.996 1.00 476.91 ? 140 ASN H OD1 1 
ATOM   9940  N ND2 . ASN D 4 140 ? 103.405 161.376 178.065 1.00 517.25 ? 140 ASN H ND2 1 
ATOM   9941  N N   . SER D 4 141 ? 105.246 157.339 180.200 1.00 377.86 ? 141 SER H N   1 
ATOM   9942  C CA  . SER D 4 141 ? 105.759 156.176 180.917 1.00 383.72 ? 141 SER H CA  1 
ATOM   9943  C C   . SER D 4 141 ? 106.484 155.189 179.993 1.00 385.10 ? 141 SER H C   1 
ATOM   9944  O O   . SER D 4 141 ? 107.447 154.561 180.429 1.00 350.63 ? 141 SER H O   1 
ATOM   9945  C CB  . SER D 4 141 ? 104.642 155.487 181.673 1.00 378.69 ? 141 SER H CB  1 
ATOM   9946  O OG  . SER D 4 141 ? 103.591 155.100 180.797 1.00 330.33 ? 141 SER H OG  1 
ATOM   9947  N N   . MET D 4 142 ? 106.006 155.054 178.739 1.00 369.53 ? 142 MET H N   1 
ATOM   9948  C CA  . MET D 4 142 ? 106.629 154.241 177.698 1.00 309.64 ? 142 MET H CA  1 
ATOM   9949  C C   . MET D 4 142 ? 107.147 155.150 176.584 1.00 326.04 ? 142 MET H C   1 
ATOM   9950  O O   . MET D 4 142 ? 106.454 156.096 176.202 1.00 377.61 ? 142 MET H O   1 
ATOM   9951  C CB  . MET D 4 142 ? 105.608 153.265 177.107 1.00 277.25 ? 142 MET H CB  1 
ATOM   9952  C CG  . MET D 4 142 ? 105.280 152.111 178.030 1.00 345.20 ? 142 MET H CG  1 
ATOM   9953  S SD  . MET D 4 142 ? 106.607 150.881 178.162 1.00 365.95 ? 142 MET H SD  1 
ATOM   9954  C CE  . MET D 4 142 ? 105.698 149.422 178.669 1.00 400.04 ? 142 MET H CE  1 
ATOM   9955  N N   . VAL D 4 143 ? 108.357 154.854 176.069 1.00 286.22 ? 143 VAL H N   1 
ATOM   9956  C CA  . VAL D 4 143 ? 109.023 155.693 175.074 1.00 271.35 ? 143 VAL H CA  1 
ATOM   9957  C C   . VAL D 4 143 ? 109.424 154.848 173.866 1.00 246.98 ? 143 VAL H C   1 
ATOM   9958  O O   . VAL D 4 143 ? 109.961 153.747 174.019 1.00 206.10 ? 143 VAL H O   1 
ATOM   9959  C CB  . VAL D 4 143 ? 110.238 156.447 175.650 1.00 316.98 ? 143 VAL H CB  1 
ATOM   9960  C CG1 . VAL D 4 143 ? 109.797 157.480 176.679 1.00 370.71 ? 143 VAL H CG1 1 
ATOM   9961  C CG2 . VAL D 4 143 ? 111.303 155.524 176.234 1.00 328.72 ? 143 VAL H CG2 1 
ATOM   9962  N N   . THR D 4 144 ? 109.145 155.397 172.668 1.00 249.96 ? 144 THR H N   1 
ATOM   9963  C CA  . THR D 4 144 ? 109.400 154.723 171.404 1.00 229.96 ? 144 THR H CA  1 
ATOM   9964  C C   . THR D 4 144 ? 110.749 155.194 170.863 1.00 230.58 ? 144 THR H C   1 
ATOM   9965  O O   . THR D 4 144 ? 111.108 156.365 171.010 1.00 220.63 ? 144 THR H O   1 
ATOM   9966  C CB  . THR D 4 144 ? 108.277 154.961 170.388 1.00 252.96 ? 144 THR H CB  1 
ATOM   9967  O OG1 . THR D 4 144 ? 107.031 154.571 170.967 1.00 322.76 ? 144 THR H OG1 1 
ATOM   9968  C CG2 . THR D 4 144 ? 108.462 154.186 169.099 1.00 259.17 ? 144 THR H CG2 1 
ATOM   9969  N N   . LEU D 4 145 ? 111.472 154.249 170.239 1.00 244.78 ? 145 LEU H N   1 
ATOM   9970  C CA  . LEU D 4 145 ? 112.777 154.472 169.633 1.00 215.97 ? 145 LEU H CA  1 
ATOM   9971  C C   . LEU D 4 145 ? 112.780 153.859 168.241 1.00 193.50 ? 145 LEU H C   1 
ATOM   9972  O O   . LEU D 4 145 ? 112.040 152.916 167.965 1.00 192.02 ? 145 LEU H O   1 
ATOM   9973  C CB  . LEU D 4 145 ? 113.848 153.807 170.491 1.00 248.28 ? 145 LEU H CB  1 
ATOM   9974  C CG  . LEU D 4 145 ? 113.881 154.211 171.962 1.00 320.32 ? 145 LEU H CG  1 
ATOM   9975  C CD1 . LEU D 4 145 ? 114.853 153.314 172.703 1.00 329.31 ? 145 LEU H CD1 1 
ATOM   9976  C CD2 . LEU D 4 145 ? 114.261 155.680 172.140 1.00 347.59 ? 145 LEU H CD2 1 
ATOM   9977  N N   . GLY D 4 146 ? 113.605 154.413 167.355 1.00 173.41 ? 146 GLY H N   1 
ATOM   9978  C CA  . GLY D 4 146 ? 113.485 154.070 165.949 1.00 178.91 ? 146 GLY H CA  1 
ATOM   9979  C C   . GLY D 4 146 ? 114.809 154.057 165.208 1.00 154.99 ? 146 GLY H C   1 
ATOM   9980  O O   . GLY D 4 146 ? 115.825 154.524 165.718 1.00 241.92 ? 146 GLY H O   1 
ATOM   9981  N N   . CYS D 4 147 ? 114.753 153.515 163.995 1.00 144.82 ? 147 CYS H N   1 
ATOM   9982  C CA  . CYS D 4 147 ? 115.931 153.275 163.189 1.00 172.66 ? 147 CYS H CA  1 
ATOM   9983  C C   . CYS D 4 147 ? 115.510 153.365 161.734 1.00 149.13 ? 147 CYS H C   1 
ATOM   9984  O O   . CYS D 4 147 ? 114.910 152.423 161.233 1.00 187.24 ? 147 CYS H O   1 
ATOM   9985  C CB  . CYS D 4 147 ? 116.518 151.911 163.535 1.00 166.77 ? 147 CYS H CB  1 
ATOM   9986  S SG  . CYS D 4 147 ? 118.115 151.569 162.756 1.00 257.05 ? 147 CYS H SG  1 
ATOM   9987  N N   . LEU D 4 148 ? 115.803 154.505 161.102 1.00 127.70 ? 148 LEU H N   1 
ATOM   9988  C CA  . LEU D 4 148 ? 115.664 154.635 159.664 1.00 162.80 ? 148 LEU H CA  1 
ATOM   9989  C C   . LEU D 4 148 ? 116.814 153.901 158.972 1.00 158.48 ? 148 LEU H C   1 
ATOM   9990  O O   . LEU D 4 148 ? 117.968 154.022 159.387 1.00 175.22 ? 148 LEU H O   1 
ATOM   9991  C CB  . LEU D 4 148 ? 115.635 156.117 159.266 1.00 171.18 ? 148 LEU H CB  1 
ATOM   9992  C CG  . LEU D 4 148 ? 115.652 156.426 157.763 1.00 159.51 ? 148 LEU H CG  1 
ATOM   9993  C CD1 . LEU D 4 148 ? 114.326 156.086 157.104 1.00 211.94 ? 148 LEU H CD1 1 
ATOM   9994  C CD2 . LEU D 4 148 ? 115.972 157.884 157.523 1.00 202.26 ? 148 LEU H CD2 1 
ATOM   9995  N N   . VAL D 4 149 ? 116.459 153.165 157.905 1.00 156.91 ? 149 VAL H N   1 
ATOM   9996  C CA  . VAL D 4 149 ? 117.379 152.508 157.001 1.00 166.17 ? 149 VAL H CA  1 
ATOM   9997  C C   . VAL D 4 149 ? 117.111 153.051 155.600 1.00 176.14 ? 149 VAL H C   1 
ATOM   9998  O O   . VAL D 4 149 ? 116.014 152.870 155.062 1.00 198.00 ? 149 VAL H O   1 
ATOM   9999  C CB  . VAL D 4 149 ? 117.166 150.989 157.076 1.00 161.48 ? 149 VAL H CB  1 
ATOM   10000 C CG1 . VAL D 4 149 ? 118.114 150.233 156.149 1.00 162.28 ? 149 VAL H CG1 1 
ATOM   10001 C CG2 . VAL D 4 149 ? 117.263 150.492 158.519 1.00 151.78 ? 149 VAL H CG2 1 
ATOM   10002 N N   . LYS D 4 150 ? 118.107 153.706 154.998 1.00 166.09 ? 150 LYS H N   1 
ATOM   10003 C CA  . LYS D 4 150 ? 117.827 154.538 153.841 1.00 204.58 ? 150 LYS H CA  1 
ATOM   10004 C C   . LYS D 4 150 ? 118.743 154.173 152.663 1.00 245.49 ? 150 LYS H C   1 
ATOM   10005 O O   . LYS D 4 150 ? 119.889 153.778 152.845 1.00 152.80 ? 150 LYS H O   1 
ATOM   10006 C CB  . LYS D 4 150 ? 117.910 156.002 154.280 1.00 200.36 ? 150 LYS H CB  1 
ATOM   10007 C CG  . LYS D 4 150 ? 117.464 156.984 153.209 1.00 238.53 ? 150 LYS H CG  1 
ATOM   10008 C CD  . LYS D 4 150 ? 117.483 158.428 153.660 1.00 293.61 ? 150 LYS H CD  1 
ATOM   10009 C CE  . LYS D 4 150 ? 117.386 159.401 152.504 1.00 355.91 ? 150 LYS H CE  1 
ATOM   10010 N NZ  . LYS D 4 150 ? 116.210 159.133 151.637 1.00 357.03 ? 150 LYS H NZ  1 
ATOM   10011 N N   . GLY D 4 151 ? 118.197 154.309 151.442 1.00 288.79 ? 151 GLY H N   1 
ATOM   10012 C CA  . GLY D 4 151 ? 118.951 154.293 150.194 1.00 268.42 ? 151 GLY H CA  1 
ATOM   10013 C C   . GLY D 4 151 ? 119.705 152.995 149.893 1.00 224.75 ? 151 GLY H C   1 
ATOM   10014 O O   . GLY D 4 151 ? 120.661 153.024 149.122 1.00 245.92 ? 151 GLY H O   1 
ATOM   10015 N N   . TYR D 4 152 ? 119.275 151.871 150.477 1.00 191.91 ? 152 TYR H N   1 
ATOM   10016 C CA  . TYR D 4 152 ? 119.973 150.598 150.354 1.00 161.27 ? 152 TYR H CA  1 
ATOM   10017 C C   . TYR D 4 152 ? 119.427 149.793 149.160 1.00 156.85 ? 152 TYR H C   1 
ATOM   10018 O O   . TYR D 4 152 ? 118.427 150.144 148.566 1.00 115.30 ? 152 TYR H O   1 
ATOM   10019 C CB  . TYR D 4 152 ? 119.829 149.869 151.691 1.00 161.05 ? 152 TYR H CB  1 
ATOM   10020 C CG  . TYR D 4 152 ? 118.511 149.145 151.941 1.00 170.66 ? 152 TYR H CG  1 
ATOM   10021 C CD1 . TYR D 4 152 ? 117.395 149.792 152.470 1.00 146.41 ? 152 TYR H CD1 1 
ATOM   10022 C CD2 . TYR D 4 152 ? 118.390 147.800 151.637 1.00 154.74 ? 152 TYR H CD2 1 
ATOM   10023 C CE1 . TYR D 4 152 ? 116.213 149.116 152.694 1.00 141.94 ? 152 TYR H CE1 1 
ATOM   10024 C CE2 . TYR D 4 152 ? 117.213 147.112 151.853 1.00 182.12 ? 152 TYR H CE2 1 
ATOM   10025 C CZ  . TYR D 4 152 ? 116.122 147.774 152.379 1.00 164.71 ? 152 TYR H CZ  1 
ATOM   10026 O OH  . TYR D 4 152 ? 114.990 147.039 152.556 1.00 210.03 ? 152 TYR H OH  1 
ATOM   10027 N N   . PHE D 4 153 ? 120.098 148.686 148.798 1.00 171.34 ? 153 PHE H N   1 
ATOM   10028 C CA  . PHE D 4 153 ? 119.669 147.756 147.748 1.00 113.74 ? 153 PHE H CA  1 
ATOM   10029 C C   . PHE D 4 153 ? 120.504 146.476 147.825 1.00 124.58 ? 153 PHE H C   1 
ATOM   10030 O O   . PHE D 4 153 ? 121.671 146.544 148.243 1.00 147.07 ? 153 PHE H O   1 
ATOM   10031 C CB  . PHE D 4 153 ? 119.907 148.401 146.390 1.00 112.65 ? 153 PHE H CB  1 
ATOM   10032 C CG  . PHE D 4 153 ? 119.193 147.775 145.236 1.00 119.81 ? 153 PHE H CG  1 
ATOM   10033 C CD1 . PHE D 4 153 ? 119.680 146.664 144.575 1.00 110.53 ? 153 PHE H CD1 1 
ATOM   10034 C CD2 . PHE D 4 153 ? 118.000 148.331 144.795 1.00 200.02 ? 153 PHE H CD2 1 
ATOM   10035 C CE1 . PHE D 4 153 ? 118.979 146.138 143.492 1.00 161.95 ? 153 PHE H CE1 1 
ATOM   10036 C CE2 . PHE D 4 153 ? 117.294 147.813 143.710 1.00 166.62 ? 153 PHE H CE2 1 
ATOM   10037 C CZ  . PHE D 4 153 ? 117.785 146.715 143.061 1.00 155.93 ? 153 PHE H CZ  1 
ATOM   10038 N N   . PRO D 4 154 ? 120.010 145.271 147.458 1.00 119.38 ? 154 PRO H N   1 
ATOM   10039 C CA  . PRO D 4 154 ? 118.626 144.969 147.122 1.00 143.32 ? 154 PRO H CA  1 
ATOM   10040 C C   . PRO D 4 154 ? 117.733 144.805 148.357 1.00 208.71 ? 154 PRO H C   1 
ATOM   10041 O O   . PRO D 4 154 ? 118.142 145.138 149.471 1.00 203.23 ? 154 PRO H O   1 
ATOM   10042 C CB  . PRO D 4 154 ? 118.710 143.639 146.361 1.00 139.00 ? 154 PRO H CB  1 
ATOM   10043 C CG  . PRO D 4 154 ? 120.182 143.403 146.159 1.00 156.36 ? 154 PRO H CG  1 
ATOM   10044 C CD  . PRO D 4 154 ? 120.813 144.061 147.362 1.00 169.65 ? 154 PRO H CD  1 
ATOM   10045 N N   . GLU D 4 155 ? 116.505 144.292 148.118 1.00 215.58 ? 155 GLU H N   1 
ATOM   10046 C CA  . GLU D 4 155 ? 115.353 144.321 149.023 1.00 191.47 ? 155 GLU H CA  1 
ATOM   10047 C C   . GLU D 4 155 ? 115.616 143.838 150.459 1.00 187.26 ? 155 GLU H C   1 
ATOM   10048 O O   . GLU D 4 155 ? 115.171 144.511 151.390 1.00 199.21 ? 155 GLU H O   1 
ATOM   10049 C CB  . GLU D 4 155 ? 114.237 143.503 148.374 1.00 189.46 ? 155 GLU H CB  1 
ATOM   10050 C CG  . GLU D 4 155 ? 113.053 143.121 149.276 1.00 317.67 ? 155 GLU H CG  1 
ATOM   10051 C CD  . GLU D 4 155 ? 112.283 144.279 149.915 1.00 366.07 ? 155 GLU H CD  1 
ATOM   10052 O OE1 . GLU D 4 155 ? 112.173 145.352 149.276 1.00 367.48 ? 155 GLU H OE1 1 
ATOM   10053 O OE2 . GLU D 4 155 ? 111.768 144.103 151.055 1.00 417.41 ? 155 GLU H OE2 1 
ATOM   10054 N N   . PRO D 4 156 ? 116.309 142.699 150.719 1.00 157.69 ? 156 PRO H N   1 
ATOM   10055 C CA  . PRO D 4 156 ? 116.311 142.087 152.059 1.00 172.70 ? 156 PRO H CA  1 
ATOM   10056 C C   . PRO D 4 156 ? 117.349 142.710 152.987 1.00 154.31 ? 156 PRO H C   1 
ATOM   10057 O O   . PRO D 4 156 ? 118.541 142.517 152.804 1.00 179.83 ? 156 PRO H O   1 
ATOM   10058 C CB  . PRO D 4 156 ? 116.676 140.636 151.790 1.00 177.80 ? 156 PRO H CB  1 
ATOM   10059 C CG  . PRO D 4 156 ? 117.567 140.740 150.555 1.00 186.16 ? 156 PRO H CG  1 
ATOM   10060 C CD  . PRO D 4 156 ? 117.147 141.962 149.766 1.00 124.09 ? 156 PRO H CD  1 
ATOM   10061 N N   . VAL D 4 157 ? 116.864 143.498 153.945 1.00 153.76 ? 157 VAL H N   1 
ATOM   10062 C CA  . VAL D 4 157 ? 117.623 143.974 155.091 1.00 137.67 ? 157 VAL H CA  1 
ATOM   10063 C C   . VAL D 4 157 ? 116.834 143.533 156.320 1.00 169.14 ? 157 VAL H C   1 
ATOM   10064 O O   . VAL D 4 157 ? 115.605 143.500 156.301 1.00 201.95 ? 157 VAL H O   1 
ATOM   10065 C CB  . VAL D 4 157 ? 117.879 145.517 155.062 1.00 154.12 ? 157 VAL H CB  1 
ATOM   10066 C CG1 . VAL D 4 157 ? 116.672 146.397 155.386 1.00 154.74 ? 157 VAL H CG1 1 
ATOM   10067 C CG2 . VAL D 4 157 ? 118.997 145.950 155.995 1.00 153.34 ? 157 VAL H CG2 1 
ATOM   10068 N N   . THR D 4 158 ? 117.561 143.218 157.389 1.00 192.69 ? 158 THR H N   1 
ATOM   10069 C CA  . THR D 4 158 ? 117.001 142.693 158.620 1.00 203.25 ? 158 THR H CA  1 
ATOM   10070 C C   . THR D 4 158 ? 117.325 143.675 159.734 1.00 171.18 ? 158 THR H C   1 
ATOM   10071 O O   . THR D 4 158 ? 118.403 144.247 159.741 1.00 224.20 ? 158 THR H O   1 
ATOM   10072 C CB  . THR D 4 158 ? 117.576 141.301 158.910 1.00 242.45 ? 158 THR H CB  1 
ATOM   10073 O OG1 . THR D 4 158 ? 117.504 140.519 157.714 1.00 293.70 ? 158 THR H OG1 1 
ATOM   10074 C CG2 . THR D 4 158 ? 116.856 140.595 160.038 1.00 275.59 ? 158 THR H CG2 1 
ATOM   10075 N N   . VAL D 4 159 ? 116.396 143.870 160.663 1.00 161.52 ? 159 VAL H N   1 
ATOM   10076 C CA  . VAL D 4 159 ? 116.677 144.627 161.873 1.00 173.26 ? 159 VAL H CA  1 
ATOM   10077 C C   . VAL D 4 159 ? 116.228 143.789 163.061 1.00 213.66 ? 159 VAL H C   1 
ATOM   10078 O O   . VAL D 4 159 ? 115.137 143.203 163.049 1.00 307.48 ? 159 VAL H O   1 
ATOM   10079 C CB  . VAL D 4 159 ? 115.985 146.004 161.887 1.00 178.74 ? 159 VAL H CB  1 
ATOM   10080 C CG1 . VAL D 4 159 ? 116.322 146.796 163.141 1.00 179.61 ? 159 VAL H CG1 1 
ATOM   10081 C CG2 . VAL D 4 159 ? 116.285 146.824 160.637 1.00 143.13 ? 159 VAL H CG2 1 
ATOM   10082 N N   . THR D 4 160 ? 117.097 143.741 164.074 1.00 182.31 ? 160 THR H N   1 
ATOM   10083 C CA  . THR D 4 160 ? 116.755 143.231 165.388 1.00 234.36 ? 160 THR H CA  1 
ATOM   10084 C C   . THR D 4 160 ? 117.337 144.208 166.393 1.00 215.37 ? 160 THR H C   1 
ATOM   10085 O O   . THR D 4 160 ? 118.327 144.863 166.087 1.00 203.52 ? 160 THR H O   1 
ATOM   10086 C CB  . THR D 4 160 ? 117.271 141.799 165.621 1.00 329.82 ? 160 THR H CB  1 
ATOM   10087 O OG1 . THR D 4 160 ? 118.694 141.750 165.497 1.00 344.77 ? 160 THR H OG1 1 
ATOM   10088 C CG2 . THR D 4 160 ? 116.676 140.792 164.661 1.00 387.95 ? 160 THR H CG2 1 
ATOM   10089 N N   . TRP D 4 161 ? 116.716 144.291 167.570 1.00 218.36 ? 161 TRP H N   1 
ATOM   10090 C CA  . TRP D 4 161 ? 117.117 145.262 168.570 1.00 231.18 ? 161 TRP H CA  1 
ATOM   10091 C C   . TRP D 4 161 ? 117.811 144.584 169.755 1.00 286.20 ? 161 TRP H C   1 
ATOM   10092 O O   . TRP D 4 161 ? 117.290 143.608 170.296 1.00 251.75 ? 161 TRP H O   1 
ATOM   10093 C CB  . TRP D 4 161 ? 115.884 146.050 169.004 1.00 211.15 ? 161 TRP H CB  1 
ATOM   10094 C CG  . TRP D 4 161 ? 115.353 146.977 167.945 1.00 195.32 ? 161 TRP H CG  1 
ATOM   10095 C CD1 . TRP D 4 161 ? 114.478 146.699 166.938 1.00 196.22 ? 161 TRP H CD1 1 
ATOM   10096 C CD2 . TRP D 4 161 ? 115.683 148.372 167.810 1.00 195.84 ? 161 TRP H CD2 1 
ATOM   10097 N NE1 . TRP D 4 161 ? 114.232 147.820 166.195 1.00 228.26 ? 161 TRP H NE1 1 
ATOM   10098 C CE2 . TRP D 4 161 ? 114.957 148.861 166.704 1.00 190.44 ? 161 TRP H CE2 1 
ATOM   10099 C CE3 . TRP D 4 161 ? 116.514 149.247 168.518 1.00 284.31 ? 161 TRP H CE3 1 
ATOM   10100 C CZ2 . TRP D 4 161 ? 115.034 150.186 166.290 1.00 171.75 ? 161 TRP H CZ2 1 
ATOM   10101 C CZ3 . TRP D 4 161 ? 116.595 150.557 168.107 1.00 318.09 ? 161 TRP H CZ3 1 
ATOM   10102 C CH2 . TRP D 4 161 ? 115.861 151.011 167.013 1.00 227.11 ? 161 TRP H CH2 1 
ATOM   10103 N N   . ASN D 4 162 ? 118.987 145.120 170.146 1.00 295.36 ? 162 ASN H N   1 
ATOM   10104 C CA  . ASN D 4 162 ? 119.860 144.562 171.178 1.00 274.92 ? 162 ASN H CA  1 
ATOM   10105 C C   . ASN D 4 162 ? 120.114 143.078 170.903 1.00 242.47 ? 162 ASN H C   1 
ATOM   10106 O O   . ASN D 4 162 ? 119.893 142.244 171.775 1.00 257.91 ? 162 ASN H O   1 
ATOM   10107 C CB  . ASN D 4 162 ? 119.321 144.848 172.591 1.00 283.41 ? 162 ASN H CB  1 
ATOM   10108 C CG  . ASN D 4 162 ? 119.506 146.286 173.042 1.00 312.77 ? 162 ASN H CG  1 
ATOM   10109 O OD1 . ASN D 4 162 ? 119.939 147.143 172.273 1.00 209.81 ? 162 ASN H OD1 1 
ATOM   10110 N ND2 . ASN D 4 162 ? 119.182 146.567 174.296 1.00 337.39 ? 162 ASN H ND2 1 
ATOM   10111 N N   . SER D 4 163 ? 120.574 142.771 169.676 1.00 261.72 ? 163 SER H N   1 
ATOM   10112 C CA  . SER D 4 163 ? 120.954 141.429 169.235 1.00 277.97 ? 163 SER H CA  1 
ATOM   10113 C C   . SER D 4 163 ? 119.816 140.407 169.406 1.00 272.79 ? 163 SER H C   1 
ATOM   10114 O O   . SER D 4 163 ? 120.071 139.244 169.718 1.00 278.74 ? 163 SER H O   1 
ATOM   10115 C CB  . SER D 4 163 ? 122.213 140.971 169.955 1.00 323.96 ? 163 SER H CB  1 
ATOM   10116 O OG  . SER D 4 163 ? 123.248 141.948 169.907 1.00 313.48 ? 163 SER H OG  1 
ATOM   10117 N N   . GLY D 4 164 ? 118.559 140.836 169.209 1.00 262.42 ? 164 GLY H N   1 
ATOM   10118 C CA  . GLY D 4 164 ? 117.385 139.984 169.367 1.00 282.76 ? 164 GLY H CA  1 
ATOM   10119 C C   . GLY D 4 164 ? 116.840 139.885 170.798 1.00 299.54 ? 164 GLY H C   1 
ATOM   10120 O O   . GLY D 4 164 ? 115.850 139.184 171.010 1.00 319.83 ? 164 GLY H O   1 
ATOM   10121 N N   . SER D 4 165 ? 117.461 140.577 171.771 1.00 312.25 ? 165 SER H N   1 
ATOM   10122 C CA  . SER D 4 165 ? 117.019 140.565 173.162 1.00 353.87 ? 165 SER H CA  1 
ATOM   10123 C C   . SER D 4 165 ? 115.673 141.273 173.329 1.00 341.01 ? 165 SER H C   1 
ATOM   10124 O O   . SER D 4 165 ? 114.830 140.785 174.084 1.00 365.26 ? 165 SER H O   1 
ATOM   10125 C CB  . SER D 4 165 ? 118.053 141.179 174.076 1.00 389.70 ? 165 SER H CB  1 
ATOM   10126 O OG  . SER D 4 165 ? 119.329 140.590 173.873 1.00 423.68 ? 165 SER H OG  1 
ATOM   10127 N N   . LEU D 4 166 ? 115.479 142.406 172.631 1.00 289.54 ? 166 LEU H N   1 
ATOM   10128 C CA  . LEU D 4 166 ? 114.226 143.155 172.672 1.00 265.49 ? 166 LEU H CA  1 
ATOM   10129 C C   . LEU D 4 166 ? 113.260 142.647 171.597 1.00 232.33 ? 166 LEU H C   1 
ATOM   10130 O O   . LEU D 4 166 ? 112.812 143.420 170.753 1.00 324.48 ? 166 LEU H O   1 
ATOM   10131 C CB  . LEU D 4 166 ? 114.536 144.651 172.487 1.00 289.14 ? 166 LEU H CB  1 
ATOM   10132 C CG  . LEU D 4 166 ? 115.292 145.333 173.628 1.00 316.54 ? 166 LEU H CG  1 
ATOM   10133 C CD1 . LEU D 4 166 ? 115.519 146.806 173.319 1.00 281.66 ? 166 LEU H CD1 1 
ATOM   10134 C CD2 . LEU D 4 166 ? 114.555 145.199 174.953 1.00 381.23 ? 166 LEU H CD2 1 
ATOM   10135 N N   . SER D 4 167 ? 112.930 141.347 171.632 1.00 231.43 ? 167 SER H N   1 
ATOM   10136 C CA  . SER D 4 167 ? 112.083 140.725 170.619 1.00 291.68 ? 167 SER H CA  1 
ATOM   10137 C C   . SER D 4 167 ? 110.593 140.997 170.857 1.00 275.00 ? 167 SER H C   1 
ATOM   10138 O O   . SER D 4 167 ? 109.780 140.614 170.012 1.00 264.16 ? 167 SER H O   1 
ATOM   10139 C CB  . SER D 4 167 ? 112.346 139.237 170.534 1.00 377.60 ? 167 SER H CB  1 
ATOM   10140 O OG  . SER D 4 167 ? 112.151 138.609 171.793 1.00 429.79 ? 167 SER H OG  1 
ATOM   10141 N N   . SER D 4 168 ? 110.238 141.642 171.989 1.00 291.60 ? 168 SER H N   1 
ATOM   10142 C CA  . SER D 4 168 ? 108.866 142.001 172.333 1.00 327.66 ? 168 SER H CA  1 
ATOM   10143 C C   . SER D 4 168 ? 108.605 143.487 172.077 1.00 293.52 ? 168 SER H C   1 
ATOM   10144 O O   . SER D 4 168 ? 109.352 144.340 172.561 1.00 295.29 ? 168 SER H O   1 
ATOM   10145 C CB  . SER D 4 168 ? 108.581 141.660 173.773 1.00 404.04 ? 168 SER H CB  1 
ATOM   10146 O OG  . SER D 4 168 ? 108.658 140.258 173.990 1.00 451.90 ? 168 SER H OG  1 
ATOM   10147 N N   . GLY D 4 169 ? 107.536 143.780 171.319 1.00 273.08 ? 169 GLY H N   1 
ATOM   10148 C CA  . GLY D 4 169 ? 107.143 145.142 171.002 1.00 295.73 ? 169 GLY H CA  1 
ATOM   10149 C C   . GLY D 4 169 ? 108.019 145.810 169.940 1.00 259.06 ? 169 GLY H C   1 
ATOM   10150 O O   . GLY D 4 169 ? 108.244 147.008 170.039 1.00 189.73 ? 169 GLY H O   1 
ATOM   10151 N N   . VAL D 4 170 ? 108.482 145.046 168.931 1.00 255.06 ? 170 VAL H N   1 
ATOM   10152 C CA  . VAL D 4 170 ? 109.178 145.578 167.763 1.00 221.93 ? 170 VAL H CA  1 
ATOM   10153 C C   . VAL D 4 170 ? 108.260 145.508 166.544 1.00 245.32 ? 170 VAL H C   1 
ATOM   10154 O O   . VAL D 4 170 ? 107.655 144.472 166.255 1.00 274.32 ? 170 VAL H O   1 
ATOM   10155 C CB  . VAL D 4 170 ? 110.487 144.827 167.468 1.00 206.30 ? 170 VAL H CB  1 
ATOM   10156 C CG1 . VAL D 4 170 ? 111.019 145.040 166.048 1.00 230.21 ? 170 VAL H CG1 1 
ATOM   10157 C CG2 . VAL D 4 170 ? 111.535 145.201 168.484 1.00 200.51 ? 170 VAL H CG2 1 
ATOM   10158 N N   . HIS D 4 171 ? 108.200 146.640 165.834 1.00 203.08 ? 171 HIS H N   1 
ATOM   10159 C CA  . HIS D 4 171 ? 107.532 146.768 164.562 1.00 176.25 ? 171 HIS H CA  1 
ATOM   10160 C C   . HIS D 4 171 ? 108.574 147.192 163.537 1.00 159.21 ? 171 HIS H C   1 
ATOM   10161 O O   . HIS D 4 171 ? 109.190 148.242 163.730 1.00 193.85 ? 171 HIS H O   1 
ATOM   10162 C CB  . HIS D 4 171 ? 106.437 147.840 164.651 1.00 184.01 ? 171 HIS H CB  1 
ATOM   10163 C CG  . HIS D 4 171 ? 105.379 147.600 165.667 1.00 196.62 ? 171 HIS H CG  1 
ATOM   10164 N ND1 . HIS D 4 171 ? 105.509 148.002 166.975 1.00 217.00 ? 171 HIS H ND1 1 
ATOM   10165 C CD2 . HIS D 4 171 ? 104.176 147.012 165.570 1.00 223.78 ? 171 HIS H CD2 1 
ATOM   10166 C CE1 . HIS D 4 171 ? 104.417 147.665 167.639 1.00 271.23 ? 171 HIS H CE1 1 
ATOM   10167 N NE2 . HIS D 4 171 ? 103.594 147.061 166.805 1.00 264.55 ? 171 HIS H NE2 1 
ATOM   10168 N N   . THR D 4 172 ? 108.751 146.393 162.472 1.00 153.38 ? 172 THR H N   1 
ATOM   10169 C CA  . THR D 4 172 ? 109.553 146.811 161.330 1.00 160.41 ? 172 THR H CA  1 
ATOM   10170 C C   . THR D 4 172 ? 108.684 146.935 160.080 1.00 162.48 ? 172 THR H C   1 
ATOM   10171 O O   . THR D 4 172 ? 108.049 145.978 159.651 1.00 195.05 ? 172 THR H O   1 
ATOM   10172 C CB  . THR D 4 172 ? 110.706 145.849 161.075 1.00 157.69 ? 172 THR H CB  1 
ATOM   10173 O OG1 . THR D 4 172 ? 111.471 145.782 162.281 1.00 154.49 ? 172 THR H OG1 1 
ATOM   10174 C CG2 . THR D 4 172 ? 111.566 146.289 159.910 1.00 153.65 ? 172 THR H CG2 1 
ATOM   10175 N N   . PHE D 4 173 ? 108.675 148.129 159.494 1.00 140.45 ? 173 PHE H N   1 
ATOM   10176 C CA  . PHE D 4 173 ? 107.755 148.454 158.422 1.00 134.68 ? 173 PHE H CA  1 
ATOM   10177 C C   . PHE D 4 173 ? 108.367 147.998 157.100 1.00 130.58 ? 173 PHE H C   1 
ATOM   10178 O O   . PHE D 4 173 ? 109.541 148.211 156.859 1.00 159.18 ? 173 PHE H O   1 
ATOM   10179 C CB  . PHE D 4 173 ? 107.435 149.944 158.468 1.00 138.66 ? 173 PHE H CB  1 
ATOM   10180 C CG  . PHE D 4 173 ? 106.989 150.392 159.839 1.00 158.80 ? 173 PHE H CG  1 
ATOM   10181 C CD1 . PHE D 4 173 ? 105.695 150.159 160.264 1.00 165.84 ? 173 PHE H CD1 1 
ATOM   10182 C CD2 . PHE D 4 173 ? 107.869 151.034 160.711 1.00 153.38 ? 173 PHE H CD2 1 
ATOM   10183 C CE1 . PHE D 4 173 ? 105.283 150.571 161.526 1.00 192.35 ? 173 PHE H CE1 1 
ATOM   10184 C CE2 . PHE D 4 173 ? 107.463 151.446 161.966 1.00 152.02 ? 173 PHE H CE2 1 
ATOM   10185 C CZ  . PHE D 4 173 ? 106.165 151.210 162.374 1.00 180.51 ? 173 PHE H CZ  1 
ATOM   10186 N N   . PRO D 4 174 ? 107.595 147.349 156.207 1.00 143.86 ? 174 PRO H N   1 
ATOM   10187 C CA  . PRO D 4 174 ? 108.033 147.030 154.854 1.00 140.62 ? 174 PRO H CA  1 
ATOM   10188 C C   . PRO D 4 174 ? 108.738 148.158 154.110 1.00 164.40 ? 174 PRO H C   1 
ATOM   10189 O O   . PRO D 4 174 ? 108.448 149.332 154.326 1.00 196.43 ? 174 PRO H O   1 
ATOM   10190 C CB  . PRO D 4 174 ? 106.710 146.780 154.123 1.00 210.16 ? 174 PRO H CB  1 
ATOM   10191 C CG  . PRO D 4 174 ? 105.827 146.176 155.174 1.00 271.45 ? 174 PRO H CG  1 
ATOM   10192 C CD  . PRO D 4 174 ? 106.234 146.864 156.459 1.00 238.67 ? 174 PRO H CD  1 
ATOM   10193 N N   . ALA D 4 175 ? 109.668 147.781 153.227 1.00 175.84 ? 175 ALA H N   1 
ATOM   10194 C CA  . ALA D 4 175 ? 110.478 148.746 152.491 1.00 155.88 ? 175 ALA H CA  1 
ATOM   10195 C C   . ALA D 4 175 ? 109.697 149.380 151.338 1.00 180.92 ? 175 ALA H C   1 
ATOM   10196 O O   . ALA D 4 175 ? 108.821 148.758 150.734 1.00 170.78 ? 175 ALA H O   1 
ATOM   10197 C CB  . ALA D 4 175 ? 111.726 148.101 151.954 1.00 180.58 ? 175 ALA H CB  1 
ATOM   10198 N N   . VAL D 4 176 ? 110.057 150.642 151.063 1.00 186.80 ? 176 VAL H N   1 
ATOM   10199 C CA  . VAL D 4 176 ? 109.524 151.461 149.993 1.00 177.76 ? 176 VAL H CA  1 
ATOM   10200 C C   . VAL D 4 176 ? 110.671 151.650 149.007 1.00 227.31 ? 176 VAL H C   1 
ATOM   10201 O O   . VAL D 4 176 ? 111.781 152.000 149.437 1.00 279.74 ? 176 VAL H O   1 
ATOM   10202 C CB  . VAL D 4 176 ? 109.044 152.833 150.528 1.00 193.25 ? 176 VAL H CB  1 
ATOM   10203 C CG1 . VAL D 4 176 ? 108.343 153.657 149.468 1.00 247.33 ? 176 VAL H CG1 1 
ATOM   10204 C CG2 . VAL D 4 176 ? 108.135 152.717 151.739 1.00 275.72 ? 176 VAL H CG2 1 
ATOM   10205 N N   . LEU D 4 177 ? 110.392 151.446 147.707 1.00 217.66 ? 177 LEU H N   1 
ATOM   10206 C CA  . LEU D 4 177 ? 111.395 151.610 146.665 1.00 213.77 ? 177 LEU H CA  1 
ATOM   10207 C C   . LEU D 4 177 ? 111.306 152.999 146.013 1.00 239.82 ? 177 LEU H C   1 
ATOM   10208 O O   . LEU D 4 177 ? 110.244 153.377 145.509 1.00 189.88 ? 177 LEU H O   1 
ATOM   10209 C CB  . LEU D 4 177 ? 111.166 150.489 145.658 1.00 210.91 ? 177 LEU H CB  1 
ATOM   10210 C CG  . LEU D 4 177 ? 112.110 150.469 144.457 1.00 269.03 ? 177 LEU H CG  1 
ATOM   10211 C CD1 . LEU D 4 177 ? 113.575 150.412 144.892 1.00 248.10 ? 177 LEU H CD1 1 
ATOM   10212 C CD2 . LEU D 4 177 ? 111.783 149.295 143.542 1.00 304.72 ? 177 LEU H CD2 1 
ATOM   10213 N N   . GLN D 4 178 ? 112.439 153.735 146.022 1.00 252.19 ? 178 GLN H N   1 
ATOM   10214 C CA  . GLN D 4 178 ? 112.534 155.097 145.504 1.00 272.15 ? 178 GLN H CA  1 
ATOM   10215 C C   . GLN D 4 178 ? 113.802 155.262 144.674 1.00 292.93 ? 178 GLN H C   1 
ATOM   10216 O O   . GLN D 4 178 ? 114.880 154.965 145.174 1.00 351.16 ? 178 GLN H O   1 
ATOM   10217 C CB  . GLN D 4 178 ? 112.555 156.109 146.653 1.00 238.45 ? 178 GLN H CB  1 
ATOM   10218 C CG  . GLN D 4 178 ? 111.202 156.311 147.305 1.00 279.34 ? 178 GLN H CG  1 
ATOM   10219 C CD  . GLN D 4 178 ? 110.216 156.949 146.355 1.00 354.79 ? 178 GLN H CD  1 
ATOM   10220 O OE1 . GLN D 4 178 ? 110.207 158.170 146.177 1.00 309.50 ? 178 GLN H OE1 1 
ATOM   10221 N NE2 . GLN D 4 178 ? 109.373 156.129 145.736 1.00 422.25 ? 178 GLN H NE2 1 
ATOM   10222 N N   . SER D 4 179 ? 113.671 155.735 143.423 1.00 278.44 ? 179 SER H N   1 
ATOM   10223 C CA  . SER D 4 179 ? 114.797 155.969 142.521 1.00 323.48 ? 179 SER H CA  1 
ATOM   10224 C C   . SER D 4 179 ? 115.781 154.788 142.520 1.00 285.19 ? 179 SER H C   1 
ATOM   10225 O O   . SER D 4 179 ? 116.995 154.981 142.610 1.00 281.16 ? 179 SER H O   1 
ATOM   10226 C CB  . SER D 4 179 ? 115.474 157.304 142.831 1.00 383.89 ? 179 SER H CB  1 
ATOM   10227 O OG  . SER D 4 179 ? 116.056 157.347 144.130 1.00 374.70 ? 179 SER H OG  1 
ATOM   10228 N N   . ASP D 4 180 ? 115.224 153.566 142.422 1.00 237.19 ? 180 ASP H N   1 
ATOM   10229 C CA  . ASP D 4 180 ? 115.944 152.291 142.416 1.00 260.65 ? 180 ASP H CA  1 
ATOM   10230 C C   . ASP D 4 180 ? 116.841 152.089 143.652 1.00 228.74 ? 180 ASP H C   1 
ATOM   10231 O O   . ASP D 4 180 ? 117.869 151.411 143.524 1.00 269.83 ? 180 ASP H O   1 
ATOM   10232 C CB  . ASP D 4 180 ? 116.721 152.100 141.097 1.00 338.21 ? 180 ASP H CB  1 
ATOM   10233 C CG  . ASP D 4 180 ? 115.865 152.127 139.836 1.00 410.13 ? 180 ASP H CG  1 
ATOM   10234 O OD1 . ASP D 4 180 ? 114.637 151.905 139.933 1.00 438.54 ? 180 ASP H OD1 1 
ATOM   10235 O OD2 . ASP D 4 180 ? 116.438 152.378 138.760 1.00 446.60 ? 180 ASP H OD2 1 
ATOM   10236 N N   . LEU D 4 181 ? 116.445 152.638 144.828 1.00 195.16 ? 181 LEU H N   1 
ATOM   10237 C CA  . LEU D 4 181 ? 117.015 152.350 146.148 1.00 174.80 ? 181 LEU H CA  1 
ATOM   10238 C C   . LEU D 4 181 ? 115.893 152.231 147.196 1.00 203.90 ? 181 LEU H C   1 
ATOM   10239 O O   . LEU D 4 181 ? 114.912 152.963 147.156 1.00 193.84 ? 181 LEU H O   1 
ATOM   10240 C CB  . LEU D 4 181 ? 117.981 153.470 146.544 1.00 183.19 ? 181 LEU H CB  1 
ATOM   10241 C CG  . LEU D 4 181 ? 119.163 153.727 145.610 1.00 266.79 ? 181 LEU H CG  1 
ATOM   10242 C CD1 . LEU D 4 181 ? 119.899 154.994 146.012 1.00 326.20 ? 181 LEU H CD1 1 
ATOM   10243 C CD2 . LEU D 4 181 ? 120.126 152.546 145.589 1.00 286.14 ? 181 LEU H CD2 1 
ATOM   10244 N N   . TYR D 4 182 ? 116.033 151.303 148.158 1.00 219.75 ? 182 TYR H N   1 
ATOM   10245 C CA  . TYR D 4 182 ? 115.000 150.999 149.151 1.00 191.57 ? 182 TYR H CA  1 
ATOM   10246 C C   . TYR D 4 182 ? 115.158 151.860 150.402 1.00 156.01 ? 182 TYR H C   1 
ATOM   10247 O O   . TYR D 4 182 ? 116.268 152.288 150.709 1.00 181.16 ? 182 TYR H O   1 
ATOM   10248 C CB  . TYR D 4 182 ? 115.039 149.524 149.555 1.00 147.05 ? 182 TYR H CB  1 
ATOM   10249 C CG  . TYR D 4 182 ? 114.637 148.601 148.413 1.00 149.45 ? 182 TYR H CG  1 
ATOM   10250 C CD1 . TYR D 4 182 ? 113.313 148.334 148.113 1.00 129.10 ? 182 TYR H CD1 1 
ATOM   10251 C CD2 . TYR D 4 182 ? 115.601 148.004 147.611 1.00 206.74 ? 182 TYR H CD2 1 
ATOM   10252 C CE1 . TYR D 4 182 ? 112.967 147.487 147.074 1.00 175.13 ? 182 TYR H CE1 1 
ATOM   10253 C CE2 . TYR D 4 182 ? 115.269 147.159 146.562 1.00 238.55 ? 182 TYR H CE2 1 
ATOM   10254 C CZ  . TYR D 4 182 ? 113.945 146.890 146.291 1.00 195.46 ? 182 TYR H CZ  1 
ATOM   10255 O OH  . TYR D 4 182 ? 113.688 146.049 145.243 1.00 190.43 ? 182 TYR H OH  1 
ATOM   10256 N N   . THR D 4 183 ? 114.028 152.105 151.089 1.00 187.16 ? 183 THR H N   1 
ATOM   10257 C CA  . THR D 4 183 ? 113.968 152.795 152.374 1.00 196.47 ? 183 THR H CA  1 
ATOM   10258 C C   . THR D 4 183 ? 113.027 152.024 153.303 1.00 182.41 ? 183 THR H C   1 
ATOM   10259 O O   . THR D 4 183 ? 111.976 151.560 152.862 1.00 198.53 ? 183 THR H O   1 
ATOM   10260 C CB  . THR D 4 183 ? 113.463 154.243 152.260 1.00 276.81 ? 183 THR H CB  1 
ATOM   10261 O OG1 . THR D 4 183 ? 114.070 154.943 151.169 1.00 290.33 ? 183 THR H OG1 1 
ATOM   10262 C CG2 . THR D 4 183 ? 113.702 155.020 153.540 1.00 323.86 ? 183 THR H CG2 1 
ATOM   10263 N N   . LEU D 4 184 ? 113.408 151.895 154.576 1.00 160.89 ? 184 LEU H N   1 
ATOM   10264 C CA  . LEU D 4 184 ? 112.753 151.023 155.541 1.00 152.86 ? 184 LEU H CA  1 
ATOM   10265 C C   . LEU D 4 184 ? 112.976 151.652 156.904 1.00 159.66 ? 184 LEU H C   1 
ATOM   10266 O O   . LEU D 4 184 ? 113.938 152.395 157.089 1.00 221.83 ? 184 LEU H O   1 
ATOM   10267 C CB  . LEU D 4 184 ? 113.389 149.624 155.455 1.00 142.71 ? 184 LEU H CB  1 
ATOM   10268 C CG  . LEU D 4 184 ? 113.076 148.645 156.590 1.00 152.32 ? 184 LEU H CG  1 
ATOM   10269 C CD1 . LEU D 4 184 ? 112.936 147.217 156.092 1.00 221.86 ? 184 LEU H CD1 1 
ATOM   10270 C CD2 . LEU D 4 184 ? 114.123 148.653 157.679 1.00 151.56 ? 184 LEU H CD2 1 
ATOM   10271 N N   . SER D 4 185 ? 112.106 151.358 157.863 1.00 147.18 ? 185 SER H N   1 
ATOM   10272 C CA  . SER D 4 185 ? 112.317 151.832 159.216 1.00 147.46 ? 185 SER H CA  1 
ATOM   10273 C C   . SER D 4 185 ? 111.808 150.812 160.221 1.00 144.06 ? 185 SER H C   1 
ATOM   10274 O O   . SER D 4 185 ? 110.915 150.027 159.946 1.00 195.85 ? 185 SER H O   1 
ATOM   10275 C CB  . SER D 4 185 ? 111.683 153.187 159.407 1.00 166.70 ? 185 SER H CB  1 
ATOM   10276 O OG  . SER D 4 185 ? 110.356 153.222 158.899 1.00 228.16 ? 185 SER H OG  1 
ATOM   10277 N N   . SER D 4 186 ? 112.399 150.832 161.402 1.00 141.11 ? 186 SER H N   1 
ATOM   10278 C CA  . SER D 4 186 ? 112.106 149.867 162.435 1.00 131.87 ? 186 SER H CA  1 
ATOM   10279 C C   . SER D 4 186 ? 111.939 150.644 163.726 1.00 154.28 ? 186 SER H C   1 
ATOM   10280 O O   . SER D 4 186 ? 112.548 151.703 163.903 1.00 200.93 ? 186 SER H O   1 
ATOM   10281 C CB  . SER D 4 186 ? 113.208 148.824 162.547 1.00 160.72 ? 186 SER H CB  1 
ATOM   10282 O OG  . SER D 4 186 ? 112.918 147.858 163.545 1.00 181.40 ? 186 SER H OG  1 
ATOM   10283 N N   . SER D 4 187 ? 111.134 150.078 164.623 1.00 181.16 ? 187 SER H N   1 
ATOM   10284 C CA  . SER D 4 187 ? 110.733 150.762 165.835 1.00 179.99 ? 187 SER H CA  1 
ATOM   10285 C C   . SER D 4 187 ? 110.553 149.766 166.972 1.00 191.22 ? 187 SER H C   1 
ATOM   10286 O O   . SER D 4 187 ? 110.203 148.607 166.749 1.00 212.68 ? 187 SER H O   1 
ATOM   10287 C CB  . SER D 4 187 ? 109.475 151.507 165.590 1.00 194.51 ? 187 SER H CB  1 
ATOM   10288 O OG  . SER D 4 187 ? 108.378 150.620 165.474 1.00 227.77 ? 187 SER H OG  1 
ATOM   10289 N N   . VAL D 4 188 ? 110.789 150.275 168.180 1.00 203.44 ? 188 VAL H N   1 
ATOM   10290 C CA  . VAL D 4 188 ? 110.683 149.513 169.403 1.00 219.21 ? 188 VAL H CA  1 
ATOM   10291 C C   . VAL D 4 188 ? 110.170 150.464 170.487 1.00 225.43 ? 188 VAL H C   1 
ATOM   10292 O O   . VAL D 4 188 ? 110.417 151.665 170.411 1.00 187.31 ? 188 VAL H O   1 
ATOM   10293 C CB  . VAL D 4 188 ? 112.056 148.892 169.720 1.00 220.01 ? 188 VAL H CB  1 
ATOM   10294 C CG1 . VAL D 4 188 ? 113.135 149.940 169.956 1.00 215.57 ? 188 VAL H CG1 1 
ATOM   10295 C CG2 . VAL D 4 188 ? 111.987 147.922 170.891 1.00 221.43 ? 188 VAL H CG2 1 
ATOM   10296 N N   . THR D 4 189 ? 109.464 149.919 171.486 1.00 225.59 ? 189 THR H N   1 
ATOM   10297 C CA  . THR D 4 189 ? 109.005 150.707 172.623 1.00 246.73 ? 189 THR H CA  1 
ATOM   10298 C C   . THR D 4 189 ? 109.463 150.035 173.921 1.00 292.88 ? 189 THR H C   1 
ATOM   10299 O O   . THR D 4 189 ? 109.354 148.814 174.061 1.00 272.18 ? 189 THR H O   1 
ATOM   10300 C CB  . THR D 4 189 ? 107.495 150.949 172.544 1.00 282.59 ? 189 THR H CB  1 
ATOM   10301 O OG1 . THR D 4 189 ? 107.219 151.704 171.361 1.00 274.70 ? 189 THR H OG1 1 
ATOM   10302 C CG2 . THR D 4 189 ? 106.958 151.697 173.744 1.00 326.61 ? 189 THR H CG2 1 
ATOM   10303 N N   . VAL D 4 190 ? 109.971 150.864 174.854 1.00 319.78 ? 190 VAL H N   1 
ATOM   10304 C CA  . VAL D 4 190 ? 110.597 150.405 176.089 1.00 318.98 ? 190 VAL H CA  1 
ATOM   10305 C C   . VAL D 4 190 ? 110.127 151.277 177.256 1.00 322.36 ? 190 VAL H C   1 
ATOM   10306 O O   . VAL D 4 190 ? 109.636 152.391 177.040 1.00 300.21 ? 190 VAL H O   1 
ATOM   10307 C CB  . VAL D 4 190 ? 112.139 150.405 175.994 1.00 288.90 ? 190 VAL H CB  1 
ATOM   10308 C CG1 . VAL D 4 190 ? 112.633 149.328 175.038 1.00 257.30 ? 190 VAL H CG1 1 
ATOM   10309 C CG2 . VAL D 4 190 ? 112.707 151.784 175.644 1.00 299.60 ? 190 VAL H CG2 1 
ATOM   10310 N N   . PRO D 4 191 ? 110.256 150.803 178.524 1.00 299.87 ? 191 PRO H N   1 
ATOM   10311 C CA  . PRO D 4 191 ? 109.978 151.652 179.685 1.00 326.19 ? 191 PRO H CA  1 
ATOM   10312 C C   . PRO D 4 191 ? 110.859 152.908 179.721 1.00 337.66 ? 191 PRO H C   1 
ATOM   10313 O O   . PRO D 4 191 ? 112.033 152.859 179.341 1.00 306.18 ? 191 PRO H O   1 
ATOM   10314 C CB  . PRO D 4 191 ? 110.296 150.744 180.888 1.00 343.43 ? 191 PRO H CB  1 
ATOM   10315 C CG  . PRO D 4 191 ? 110.194 149.332 180.345 1.00 307.65 ? 191 PRO H CG  1 
ATOM   10316 C CD  . PRO D 4 191 ? 110.667 149.437 178.915 1.00 252.47 ? 191 PRO H CD  1 
ATOM   10317 N N   . SER D 4 192 ? 110.279 154.026 180.186 1.00 359.91 ? 192 SER H N   1 
ATOM   10318 C CA  . SER D 4 192 ? 110.984 155.300 180.318 1.00 365.80 ? 192 SER H CA  1 
ATOM   10319 C C   . SER D 4 192 ? 112.167 155.229 181.293 1.00 336.22 ? 192 SER H C   1 
ATOM   10320 O O   . SER D 4 192 ? 113.063 156.068 181.206 1.00 312.72 ? 192 SER H O   1 
ATOM   10321 C CB  . SER D 4 192 ? 110.024 156.407 180.713 1.00 383.32 ? 192 SER H CB  1 
ATOM   10322 O OG  . SER D 4 192 ? 109.267 156.048 181.862 1.00 373.67 ? 192 SER H OG  1 
ATOM   10323 N N   . SER D 4 193 ? 112.163 154.246 182.213 1.00 338.90 ? 193 SER H N   1 
ATOM   10324 C CA  . SER D 4 193 ? 113.310 153.918 183.055 1.00 371.36 ? 193 SER H CA  1 
ATOM   10325 C C   . SER D 4 193 ? 114.500 153.368 182.258 1.00 339.87 ? 193 SER H C   1 
ATOM   10326 O O   . SER D 4 193 ? 115.651 153.638 182.614 1.00 343.17 ? 193 SER H O   1 
ATOM   10327 C CB  . SER D 4 193 ? 112.901 152.943 184.140 1.00 379.12 ? 193 SER H CB  1 
ATOM   10328 O OG  . SER D 4 193 ? 112.381 151.741 183.590 1.00 328.92 ? 193 SER H OG  1 
ATOM   10329 N N   . THR D 4 194 ? 114.217 152.597 181.194 1.00 294.14 ? 194 THR H N   1 
ATOM   10330 C CA  . THR D 4 194 ? 115.228 151.848 180.457 1.00 321.70 ? 194 THR H CA  1 
ATOM   10331 C C   . THR D 4 194 ? 116.076 152.773 179.573 1.00 290.68 ? 194 THR H C   1 
ATOM   10332 O O   . THR D 4 194 ? 117.295 152.734 179.686 1.00 315.05 ? 194 THR H O   1 
ATOM   10333 C CB  . THR D 4 194 ? 114.581 150.679 179.686 1.00 374.78 ? 194 THR H CB  1 
ATOM   10334 O OG1 . THR D 4 194 ? 114.418 149.601 180.609 1.00 338.52 ? 194 THR H OG1 1 
ATOM   10335 C CG2 . THR D 4 194 ? 115.367 150.171 178.494 1.00 419.75 ? 194 THR H CG2 1 
ATOM   10336 N N   . TRP D 4 195 ? 115.472 153.586 178.692 1.00 258.29 ? 195 TRP H N   1 
ATOM   10337 C CA  . TRP D 4 195 ? 116.203 154.078 177.522 1.00 258.00 ? 195 TRP H CA  1 
ATOM   10338 C C   . TRP D 4 195 ? 117.430 154.927 177.886 1.00 293.55 ? 195 TRP H C   1 
ATOM   10339 O O   . TRP D 4 195 ? 118.515 154.588 177.425 1.00 301.91 ? 195 TRP H O   1 
ATOM   10340 C CB  . TRP D 4 195 ? 115.295 154.819 176.527 1.00 290.60 ? 195 TRP H CB  1 
ATOM   10341 C CG  . TRP D 4 195 ? 116.080 155.657 175.547 1.00 299.36 ? 195 TRP H CG  1 
ATOM   10342 C CD1 . TRP D 4 195 ? 117.143 155.241 174.797 1.00 249.30 ? 195 TRP H CD1 1 
ATOM   10343 C CD2 . TRP D 4 195 ? 115.868 157.048 175.213 1.00 352.25 ? 195 TRP H CD2 1 
ATOM   10344 N NE1 . TRP D 4 195 ? 117.609 156.268 174.024 1.00 303.36 ? 195 TRP H NE1 1 
ATOM   10345 C CE2 . TRP D 4 195 ? 116.850 157.387 174.251 1.00 352.22 ? 195 TRP H CE2 1 
ATOM   10346 C CE3 . TRP D 4 195 ? 114.955 158.032 175.624 1.00 382.03 ? 195 TRP H CE3 1 
ATOM   10347 C CZ2 . TRP D 4 195 ? 116.937 158.667 173.699 1.00 387.18 ? 195 TRP H CZ2 1 
ATOM   10348 C CZ3 . TRP D 4 195 ? 115.044 159.296 175.078 1.00 391.95 ? 195 TRP H CZ3 1 
ATOM   10349 C CH2 . TRP D 4 195 ? 116.023 159.607 174.128 1.00 392.42 ? 195 TRP H CH2 1 
ATOM   10350 N N   . PRO D 4 196 ? 117.362 156.030 178.679 1.00 356.62 ? 196 PRO H N   1 
ATOM   10351 C CA  . PRO D 4 196 ? 118.587 156.743 179.077 1.00 387.25 ? 196 PRO H CA  1 
ATOM   10352 C C   . PRO D 4 196 ? 119.569 155.968 179.973 1.00 380.58 ? 196 PRO H C   1 
ATOM   10353 O O   . PRO D 4 196 ? 120.725 156.381 180.085 1.00 354.41 ? 196 PRO H O   1 
ATOM   10354 C CB  . PRO D 4 196 ? 118.057 157.982 179.832 1.00 391.35 ? 196 PRO H CB  1 
ATOM   10355 C CG  . PRO D 4 196 ? 116.612 158.106 179.400 1.00 351.56 ? 196 PRO H CG  1 
ATOM   10356 C CD  . PRO D 4 196 ? 116.155 156.672 179.228 1.00 362.11 ? 196 PRO H CD  1 
ATOM   10357 N N   . SER D 4 197 ? 119.111 154.861 180.595 1.00 373.02 ? 197 SER H N   1 
ATOM   10358 C CA  . SER D 4 197 ? 119.869 154.076 181.563 1.00 397.99 ? 197 SER H CA  1 
ATOM   10359 C C   . SER D 4 197 ? 120.661 152.916 180.940 1.00 419.86 ? 197 SER H C   1 
ATOM   10360 O O   . SER D 4 197 ? 121.582 152.420 181.586 1.00 434.34 ? 197 SER H O   1 
ATOM   10361 C CB  . SER D 4 197 ? 118.931 153.540 182.629 1.00 398.82 ? 197 SER H CB  1 
ATOM   10362 O OG  . SER D 4 197 ? 118.109 154.568 183.172 1.00 374.27 ? 197 SER H OG  1 
ATOM   10363 N N   . GLU D 4 198 ? 120.314 152.483 179.711 1.00 420.00 ? 198 GLU H N   1 
ATOM   10364 C CA  . GLU D 4 198 ? 120.763 151.213 179.146 1.00 398.34 ? 198 GLU H CA  1 
ATOM   10365 C C   . GLU D 4 198 ? 121.155 151.362 177.672 1.00 401.74 ? 198 GLU H C   1 
ATOM   10366 O O   . GLU D 4 198 ? 120.825 152.349 177.016 1.00 420.22 ? 198 GLU H O   1 
ATOM   10367 C CB  . GLU D 4 198 ? 119.656 150.160 179.257 1.00 374.99 ? 198 GLU H CB  1 
ATOM   10368 C CG  . GLU D 4 198 ? 119.139 149.919 180.667 1.00 403.35 ? 198 GLU H CG  1 
ATOM   10369 C CD  . GLU D 4 198 ? 118.170 148.750 180.767 1.00 437.38 ? 198 GLU H CD  1 
ATOM   10370 O OE1 . GLU D 4 198 ? 118.598 147.611 180.494 1.00 456.91 ? 198 GLU H OE1 1 
ATOM   10371 O OE2 . GLU D 4 198 ? 116.988 148.979 181.110 1.00 445.14 ? 198 GLU H OE2 1 
ATOM   10372 N N   . THR D 4 199 ? 121.873 150.356 177.151 1.00 400.44 ? 199 THR H N   1 
ATOM   10373 C CA  . THR D 4 199 ? 122.190 150.266 175.731 1.00 421.15 ? 199 THR H CA  1 
ATOM   10374 C C   . THR D 4 199 ? 120.919 149.951 174.942 1.00 426.96 ? 199 THR H C   1 
ATOM   10375 O O   . THR D 4 199 ? 120.168 149.054 175.324 1.00 420.72 ? 199 THR H O   1 
ATOM   10376 C CB  . THR D 4 199 ? 123.260 149.196 175.460 1.00 466.44 ? 199 THR H CB  1 
ATOM   10377 O OG1 . THR D 4 199 ? 124.456 149.574 176.145 1.00 456.26 ? 199 THR H OG1 1 
ATOM   10378 C CG2 . THR D 4 199 ? 123.589 149.005 173.994 1.00 498.15 ? 199 THR H CG2 1 
ATOM   10379 N N   . VAL D 4 200 ? 120.688 150.693 173.844 1.00 393.24 ? 200 VAL H N   1 
ATOM   10380 C CA  . VAL D 4 200 ? 119.721 150.311 172.816 1.00 298.76 ? 200 VAL H CA  1 
ATOM   10381 C C   . VAL D 4 200 ? 120.371 150.458 171.438 1.00 267.89 ? 200 VAL H C   1 
ATOM   10382 O O   . VAL D 4 200 ? 120.868 151.536 171.125 1.00 214.55 ? 200 VAL H O   1 
ATOM   10383 C CB  . VAL D 4 200 ? 118.422 151.134 172.890 1.00 267.67 ? 200 VAL H CB  1 
ATOM   10384 C CG1 . VAL D 4 200 ? 117.407 150.630 171.877 1.00 251.34 ? 200 VAL H CG1 1 
ATOM   10385 C CG2 . VAL D 4 200 ? 117.814 151.148 174.286 1.00 281.33 ? 200 VAL H CG2 1 
ATOM   10386 N N   . THR D 4 201 ? 120.351 149.380 170.627 1.00 263.75 ? 201 THR H N   1 
ATOM   10387 C CA  . THR D 4 201 ? 120.878 149.386 169.262 1.00 285.74 ? 201 THR H CA  1 
ATOM   10388 C C   . THR D 4 201 ? 119.921 148.706 168.287 1.00 259.83 ? 201 THR H C   1 
ATOM   10389 O O   . THR D 4 201 ? 119.408 147.636 168.591 1.00 228.12 ? 201 THR H O   1 
ATOM   10390 C CB  . THR D 4 201 ? 122.221 148.651 169.123 1.00 274.74 ? 201 THR H CB  1 
ATOM   10391 O OG1 . THR D 4 201 ? 122.117 147.323 169.642 1.00 206.42 ? 201 THR H OG1 1 
ATOM   10392 C CG2 . THR D 4 201 ? 123.349 149.364 169.828 1.00 311.98 ? 201 THR H CG2 1 
ATOM   10393 N N   . CYS D 4 202 ? 119.699 149.327 167.117 1.00 231.06 ? 202 CYS H N   1 
ATOM   10394 C CA  . CYS D 4 202 ? 119.225 148.583 165.962 1.00 226.24 ? 202 CYS H CA  1 
ATOM   10395 C C   . CYS D 4 202 ? 120.426 147.861 165.339 1.00 202.08 ? 202 CYS H C   1 
ATOM   10396 O O   . CYS D 4 202 ? 121.350 148.502 164.842 1.00 186.02 ? 202 CYS H O   1 
ATOM   10397 C CB  . CYS D 4 202 ? 118.473 149.455 164.958 1.00 259.67 ? 202 CYS H CB  1 
ATOM   10398 S SG  . CYS D 4 202 ? 119.336 150.901 164.287 1.00 397.57 ? 202 CYS H SG  1 
ATOM   10399 N N   . ASN D 4 203 ? 120.396 146.516 165.387 1.00 202.60 ? 203 ASN H N   1 
ATOM   10400 C CA  . ASN D 4 203 ? 121.406 145.657 164.784 1.00 242.45 ? 203 ASN H CA  1 
ATOM   10401 C C   . ASN D 4 203 ? 121.050 145.375 163.318 1.00 198.21 ? 203 ASN H C   1 
ATOM   10402 O O   . ASN D 4 203 ? 120.687 144.248 162.965 1.00 157.84 ? 203 ASN H O   1 
ATOM   10403 C CB  . ASN D 4 203 ? 121.578 144.337 165.555 1.00 305.20 ? 203 ASN H CB  1 
ATOM   10404 C CG  . ASN D 4 203 ? 122.015 144.460 167.006 1.00 324.23 ? 203 ASN H CG  1 
ATOM   10405 O OD1 . ASN D 4 203 ? 121.527 145.299 167.761 1.00 303.58 ? 203 ASN H OD1 1 
ATOM   10406 N ND2 . ASN D 4 203 ? 122.927 143.600 167.432 1.00 322.82 ? 203 ASN H ND2 1 
ATOM   10407 N N   . VAL D 4 204 ? 121.186 146.406 162.464 1.00 159.59 ? 204 VAL H N   1 
ATOM   10408 C CA  . VAL D 4 204 ? 120.855 146.306 161.046 1.00 181.23 ? 204 VAL H CA  1 
ATOM   10409 C C   . VAL D 4 204 ? 121.838 145.366 160.351 1.00 191.64 ? 204 VAL H C   1 
ATOM   10410 O O   . VAL D 4 204 ? 123.020 145.409 160.643 1.00 248.01 ? 204 VAL H O   1 
ATOM   10411 C CB  . VAL D 4 204 ? 120.861 147.672 160.337 1.00 167.84 ? 204 VAL H CB  1 
ATOM   10412 C CG1 . VAL D 4 204 ? 120.609 147.546 158.823 1.00 158.14 ? 204 VAL H CG1 1 
ATOM   10413 C CG2 . VAL D 4 204 ? 119.877 148.626 160.986 1.00 182.84 ? 204 VAL H CG2 1 
ATOM   10414 N N   . ALA D 4 205 ? 121.333 144.536 159.436 1.00 160.51 ? 205 ALA H N   1 
ATOM   10415 C CA  . ALA D 4 205 ? 122.118 143.499 158.797 1.00 197.48 ? 205 ALA H CA  1 
ATOM   10416 C C   . ALA D 4 205 ? 121.646 143.321 157.367 1.00 190.95 ? 205 ALA H C   1 
ATOM   10417 O O   . ALA D 4 205 ? 120.450 143.345 157.120 1.00 272.26 ? 205 ALA H O   1 
ATOM   10418 C CB  . ALA D 4 205 ? 121.987 142.198 159.562 1.00 281.45 ? 205 ALA H CB  1 
ATOM   10419 N N   . HIS D 4 206 ? 122.587 143.113 156.440 1.00 179.79 ? 206 HIS H N   1 
ATOM   10420 C CA  . HIS D 4 206 ? 122.284 143.113 155.018 1.00 183.09 ? 206 HIS H CA  1 
ATOM   10421 C C   . HIS D 4 206 ? 122.981 141.922 154.357 1.00 180.65 ? 206 HIS H C   1 
ATOM   10422 O O   . HIS D 4 206 ? 124.156 142.021 154.057 1.00 199.20 ? 206 HIS H O   1 
ATOM   10423 C CB  . HIS D 4 206 ? 122.646 144.487 154.447 1.00 175.36 ? 206 HIS H CB  1 
ATOM   10424 C CG  . HIS D 4 206 ? 122.231 144.740 153.035 1.00 179.76 ? 206 HIS H CG  1 
ATOM   10425 N ND1 . HIS D 4 206 ? 122.539 143.935 151.965 1.00 229.16 ? 206 HIS H ND1 1 
ATOM   10426 C CD2 . HIS D 4 206 ? 121.536 145.752 152.519 1.00 169.10 ? 206 HIS H CD2 1 
ATOM   10427 C CE1 . HIS D 4 206 ? 122.029 144.458 150.858 1.00 195.86 ? 206 HIS H CE1 1 
ATOM   10428 N NE2 . HIS D 4 206 ? 121.416 145.553 151.171 1.00 133.25 ? 206 HIS H NE2 1 
ATOM   10429 N N   . PRO D 4 207 ? 122.291 140.787 154.100 1.00 223.03 ? 207 PRO H N   1 
ATOM   10430 C CA  . PRO D 4 207 ? 122.880 139.626 153.430 1.00 241.86 ? 207 PRO H CA  1 
ATOM   10431 C C   . PRO D 4 207 ? 123.608 139.844 152.106 1.00 264.06 ? 207 PRO H C   1 
ATOM   10432 O O   . PRO D 4 207 ? 124.618 139.181 151.853 1.00 354.02 ? 207 PRO H O   1 
ATOM   10433 C CB  . PRO D 4 207 ? 121.651 138.753 153.108 1.00 289.62 ? 207 PRO H CB  1 
ATOM   10434 C CG  . PRO D 4 207 ? 120.696 139.059 154.235 1.00 350.85 ? 207 PRO H CG  1 
ATOM   10435 C CD  . PRO D 4 207 ? 120.888 140.540 154.454 1.00 313.19 ? 207 PRO H CD  1 
ATOM   10436 N N   . ALA D 4 208 ? 123.089 140.752 151.270 1.00 214.88 ? 208 ALA H N   1 
ATOM   10437 C CA  . ALA D 4 208 ? 123.562 140.875 149.893 1.00 237.61 ? 208 ALA H CA  1 
ATOM   10438 C C   . ALA D 4 208 ? 124.787 141.799 149.759 1.00 211.40 ? 208 ALA H C   1 
ATOM   10439 O O   . ALA D 4 208 ? 125.366 141.828 148.678 1.00 193.93 ? 208 ALA H O   1 
ATOM   10440 C CB  . ALA D 4 208 ? 122.405 141.289 148.998 1.00 224.78 ? 208 ALA H CB  1 
ATOM   10441 N N   . SER D 4 209 ? 125.188 142.539 150.812 1.00 222.89 ? 209 SER H N   1 
ATOM   10442 C CA  . SER D 4 209 ? 126.455 143.270 150.812 1.00 256.30 ? 209 SER H CA  1 
ATOM   10443 C C   . SER D 4 209 ? 127.231 143.162 152.136 1.00 272.17 ? 209 SER H C   1 
ATOM   10444 O O   . SER D 4 209 ? 128.101 143.998 152.388 1.00 251.38 ? 209 SER H O   1 
ATOM   10445 C CB  . SER D 4 209 ? 126.233 144.728 150.404 1.00 259.85 ? 209 SER H CB  1 
ATOM   10446 O OG  . SER D 4 209 ? 125.699 145.532 151.447 1.00 194.25 ? 209 SER H OG  1 
ATOM   10447 N N   . SER D 4 210 ? 126.926 142.145 152.970 1.00 280.64 ? 210 SER H N   1 
ATOM   10448 C CA  . SER D 4 210 ? 127.722 141.702 154.115 1.00 345.60 ? 210 SER H CA  1 
ATOM   10449 C C   . SER D 4 210 ? 127.935 142.748 155.229 1.00 344.86 ? 210 SER H C   1 
ATOM   10450 O O   . SER D 4 210 ? 128.741 142.492 156.126 1.00 395.21 ? 210 SER H O   1 
ATOM   10451 C CB  . SER D 4 210 ? 129.041 141.119 153.623 1.00 372.19 ? 210 SER H CB  1 
ATOM   10452 O OG  . SER D 4 210 ? 128.816 140.022 152.744 1.00 336.24 ? 210 SER H OG  1 
ATOM   10453 N N   . THR D 4 211 ? 127.224 143.896 155.218 1.00 272.37 ? 211 THR H N   1 
ATOM   10454 C CA  . THR D 4 211 ? 127.394 144.934 156.235 1.00 290.70 ? 211 THR H CA  1 
ATOM   10455 C C   . THR D 4 211 ? 126.491 144.669 157.441 1.00 267.15 ? 211 THR H C   1 
ATOM   10456 O O   . THR D 4 211 ? 125.308 144.407 157.269 1.00 255.47 ? 211 THR H O   1 
ATOM   10457 C CB  . THR D 4 211 ? 127.095 146.338 155.694 1.00 326.43 ? 211 THR H CB  1 
ATOM   10458 O OG1 . THR D 4 211 ? 125.796 146.329 155.103 1.00 351.79 ? 211 THR H OG1 1 
ATOM   10459 C CG2 . THR D 4 211 ? 128.119 146.799 154.683 1.00 347.48 ? 211 THR H CG2 1 
ATOM   10460 N N   . LYS D 4 212 ? 127.067 144.752 158.649 1.00 278.26 ? 212 LYS H N   1 
ATOM   10461 C CA  . LYS D 4 212 ? 126.356 144.604 159.912 1.00 273.30 ? 212 LYS H CA  1 
ATOM   10462 C C   . LYS D 4 212 ? 126.725 145.791 160.801 1.00 278.19 ? 212 LYS H C   1 
ATOM   10463 O O   . LYS D 4 212 ? 127.908 146.063 161.000 1.00 348.13 ? 212 LYS H O   1 
ATOM   10464 C CB  . LYS D 4 212 ? 126.713 143.277 160.591 1.00 293.71 ? 212 LYS H CB  1 
ATOM   10465 C CG  . LYS D 4 212 ? 126.427 142.023 159.773 1.00 345.26 ? 212 LYS H CG  1 
ATOM   10466 C CD  . LYS D 4 212 ? 126.929 140.734 160.416 1.00 397.21 ? 212 LYS H CD  1 
ATOM   10467 C CE  . LYS D 4 212 ? 126.250 140.357 161.720 1.00 440.60 ? 212 LYS H CE  1 
ATOM   10468 N NZ  . LYS D 4 212 ? 124.821 140.001 161.539 1.00 473.20 ? 212 LYS H NZ  1 
ATOM   10469 N N   . VAL D 4 213 ? 125.710 146.497 161.327 1.00 240.95 ? 213 VAL H N   1 
ATOM   10470 C CA  . VAL D 4 213 ? 125.899 147.799 161.954 1.00 233.60 ? 213 VAL H CA  1 
ATOM   10471 C C   . VAL D 4 213 ? 124.969 147.929 163.161 1.00 219.26 ? 213 VAL H C   1 
ATOM   10472 O O   . VAL D 4 213 ? 123.792 147.570 163.083 1.00 223.27 ? 213 VAL H O   1 
ATOM   10473 C CB  . VAL D 4 213 ? 125.656 148.950 160.953 1.00 245.98 ? 213 VAL H CB  1 
ATOM   10474 C CG1 . VAL D 4 213 ? 125.934 150.309 161.600 1.00 241.29 ? 213 VAL H CG1 1 
ATOM   10475 C CG2 . VAL D 4 213 ? 126.437 148.779 159.644 1.00 214.31 ? 213 VAL H CG2 1 
ATOM   10476 N N   . ASP D 4 214 ? 125.516 148.471 164.265 1.00 265.33 ? 214 ASP H N   1 
ATOM   10477 C CA  . ASP D 4 214 ? 124.847 148.554 165.559 1.00 320.97 ? 214 ASP H CA  1 
ATOM   10478 C C   . ASP D 4 214 ? 124.860 150.011 166.041 1.00 280.03 ? 214 ASP H C   1 
ATOM   10479 O O   . ASP D 4 214 ? 125.615 150.373 166.943 1.00 321.15 ? 214 ASP H O   1 
ATOM   10480 C CB  . ASP D 4 214 ? 125.486 147.597 166.583 1.00 391.50 ? 214 ASP H CB  1 
ATOM   10481 C CG  . ASP D 4 214 ? 125.664 146.150 166.134 1.00 384.18 ? 214 ASP H CG  1 
ATOM   10482 O OD1 . ASP D 4 214 ? 124.734 145.608 165.508 1.00 357.49 ? 214 ASP H OD1 1 
ATOM   10483 O OD2 . ASP D 4 214 ? 126.737 145.567 166.418 1.00 392.12 ? 214 ASP H OD2 1 
ATOM   10484 N N   . LYS D 4 215 ? 124.011 150.853 165.438 1.00 247.13 ? 215 LYS H N   1 
ATOM   10485 C CA  . LYS D 4 215 ? 123.859 152.243 165.844 1.00 272.14 ? 215 LYS H CA  1 
ATOM   10486 C C   . LYS D 4 215 ? 123.159 152.322 167.205 1.00 261.02 ? 215 LYS H C   1 
ATOM   10487 O O   . LYS D 4 215 ? 122.082 151.755 167.381 1.00 217.04 ? 215 LYS H O   1 
ATOM   10488 C CB  . LYS D 4 215 ? 123.052 153.019 164.796 1.00 316.74 ? 215 LYS H CB  1 
ATOM   10489 C CG  . LYS D 4 215 ? 123.785 153.361 163.504 1.00 311.42 ? 215 LYS H CG  1 
ATOM   10490 C CD  . LYS D 4 215 ? 124.937 154.342 163.644 1.00 359.65 ? 215 LYS H CD  1 
ATOM   10491 C CE  . LYS D 4 215 ? 124.540 155.698 164.192 1.00 392.89 ? 215 LYS H CE  1 
ATOM   10492 N NZ  . LYS D 4 215 ? 125.706 156.609 164.262 1.00 408.33 ? 215 LYS H NZ  1 
ATOM   10493 N N   . LYS D 4 216 ? 123.774 153.035 168.160 1.00 275.12 ? 216 LYS H N   1 
ATOM   10494 C CA  . LYS D 4 216 ? 123.190 153.252 169.476 1.00 315.59 ? 216 LYS H CA  1 
ATOM   10495 C C   . LYS D 4 216 ? 122.254 154.457 169.439 1.00 287.78 ? 216 LYS H C   1 
ATOM   10496 O O   . LYS D 4 216 ? 122.583 155.466 168.817 1.00 317.08 ? 216 LYS H O   1 
ATOM   10497 C CB  . LYS D 4 216 ? 124.284 153.484 170.524 1.00 405.32 ? 216 LYS H CB  1 
ATOM   10498 C CG  . LYS D 4 216 ? 125.068 152.245 170.924 1.00 416.95 ? 216 LYS H CG  1 
ATOM   10499 C CD  . LYS D 4 216 ? 126.046 152.504 172.053 1.00 442.24 ? 216 LYS H CD  1 
ATOM   10500 C CE  . LYS D 4 216 ? 126.783 151.265 172.514 1.00 463.75 ? 216 LYS H CE  1 
ATOM   10501 N NZ  . LYS D 4 216 ? 127.680 150.724 171.464 1.00 485.95 ? 216 LYS H NZ  1 
ATOM   10502 N N   . ILE D 4 217 ? 121.109 154.347 170.133 1.00 235.83 ? 217 ILE H N   1 
ATOM   10503 C CA  . ILE D 4 217 ? 120.106 155.402 170.166 1.00 279.45 ? 217 ILE H CA  1 
ATOM   10504 C C   . ILE D 4 217 ? 120.432 156.350 171.328 1.00 299.05 ? 217 ILE H C   1 
ATOM   10505 O O   . ILE D 4 217 ? 120.011 156.121 172.467 1.00 255.88 ? 217 ILE H O   1 
ATOM   10506 C CB  . ILE D 4 217 ? 118.674 154.834 170.274 1.00 321.41 ? 217 ILE H CB  1 
ATOM   10507 C CG1 . ILE D 4 217 ? 118.424 153.601 169.395 1.00 336.10 ? 217 ILE H CG1 1 
ATOM   10508 C CG2 . ILE D 4 217 ? 117.653 155.936 170.004 1.00 348.21 ? 217 ILE H CG2 1 
ATOM   10509 C CD1 . ILE D 4 217 ? 118.716 153.771 167.932 1.00 310.86 ? 217 ILE H CD1 1 
ATOM   10510 N N   . VAL D 4 218 ? 121.178 157.427 171.018 1.00 305.84 ? 218 VAL H N   1 
ATOM   10511 C CA  . VAL D 4 218 ? 121.670 158.380 172.003 1.00 319.84 ? 218 VAL H CA  1 
ATOM   10512 C C   . VAL D 4 218 ? 120.764 159.618 171.999 1.00 313.57 ? 218 VAL H C   1 
ATOM   10513 O O   . VAL D 4 218 ? 120.423 160.113 170.920 1.00 279.08 ? 218 VAL H O   1 
ATOM   10514 C CB  . VAL D 4 218 ? 123.140 158.753 171.723 1.00 381.57 ? 218 VAL H CB  1 
ATOM   10515 C CG1 . VAL D 4 218 ? 123.692 159.742 172.744 1.00 444.69 ? 218 VAL H CG1 1 
ATOM   10516 C CG2 . VAL D 4 218 ? 124.035 157.522 171.654 1.00 367.77 ? 218 VAL H CG2 1 
ATOM   10517 N N   . PRO D 4 219 ? 120.352 160.169 173.179 1.00 313.82 ? 219 PRO H N   1 
ATOM   10518 C CA  . PRO D 4 219 ? 119.554 161.409 173.227 1.00 306.45 ? 219 PRO H CA  1 
ATOM   10519 C C   . PRO D 4 219 ? 120.210 162.641 172.584 1.00 307.38 ? 219 PRO H C   1 
ATOM   10520 O O   . PRO D 4 219 ? 121.430 162.702 172.433 1.00 327.96 ? 219 PRO H O   1 
ATOM   10521 C CB  . PRO D 4 219 ? 119.363 161.683 174.734 1.00 324.02 ? 219 PRO H CB  1 
ATOM   10522 C CG  . PRO D 4 219 ? 119.636 160.354 175.424 1.00 313.67 ? 219 PRO H CG  1 
ATOM   10523 C CD  . PRO D 4 219 ? 120.616 159.629 174.530 1.00 292.17 ? 219 PRO H CD  1 
ATOM   10524 N N   . ARG D 4 220 ? 119.387 163.633 172.214 1.00 332.38 ? 220 ARG H N   1 
ATOM   10525 C CA  . ARG D 4 220 ? 119.845 164.804 171.475 1.00 365.18 ? 220 ARG H CA  1 
ATOM   10526 C C   . ARG D 4 220 ? 120.579 165.776 172.415 1.00 376.21 ? 220 ARG H C   1 
ATOM   10527 O O   . ARG D 4 220 ? 119.903 166.421 173.245 1.00 350.31 ? 220 ARG H O   1 
ATOM   10528 C CB  . ARG D 4 220 ? 118.660 165.476 170.771 1.00 348.20 ? 220 ARG H CB  1 
ATOM   10529 C CG  . ARG D 4 220 ? 117.968 164.582 169.753 1.00 317.75 ? 220 ARG H CG  1 
ATOM   10530 C CD  . ARG D 4 220 ? 116.772 165.254 169.102 1.00 349.42 ? 220 ARG H CD  1 
ATOM   10531 N NE  . ARG D 4 220 ? 117.144 166.299 168.150 1.00 375.97 ? 220 ARG H NE  1 
ATOM   10532 C CZ  . ARG D 4 220 ? 117.535 166.110 166.884 1.00 414.79 ? 220 ARG H CZ  1 
ATOM   10533 N NH1 . ARG D 4 220 ? 117.632 164.892 166.373 1.00 411.02 ? 220 ARG H NH1 1 
ATOM   10534 N NH2 . ARG D 4 220 ? 117.828 167.152 166.119 1.00 410.73 ? 220 ARG H NH2 1 
HETATM 10535 C C1  . NAG E 5 .   ? 110.722 78.446  150.747 1.00 250.79 ? 701 NAG A C1  1 
HETATM 10536 C C2  . NAG E 5 .   ? 109.978 79.159  151.875 1.00 271.12 ? 701 NAG A C2  1 
HETATM 10537 C C3  . NAG E 5 .   ? 110.875 79.235  153.109 1.00 386.11 ? 701 NAG A C3  1 
HETATM 10538 C C4  . NAG E 5 .   ? 111.333 77.837  153.499 1.00 375.51 ? 701 NAG A C4  1 
HETATM 10539 C C5  . NAG E 5 .   ? 112.019 77.180  152.302 1.00 297.93 ? 701 NAG A C5  1 
HETATM 10540 C C6  . NAG E 5 .   ? 112.452 75.775  152.639 1.00 331.23 ? 701 NAG A C6  1 
HETATM 10541 C C7  . NAG E 5 .   ? 108.273 80.734  150.999 1.00 324.59 ? 701 NAG A C7  1 
HETATM 10542 C C8  . NAG E 5 .   ? 107.814 82.165  151.030 1.00 311.09 ? 701 NAG A C8  1 
HETATM 10543 N N2  . NAG E 5 .   ? 109.499 80.482  151.501 1.00 272.39 ? 701 NAG A N2  1 
HETATM 10544 O O3  . NAG E 5 .   ? 110.221 79.861  154.208 1.00 494.30 ? 701 NAG A O3  1 
HETATM 10545 O O4  . NAG E 5 .   ? 112.242 77.926  154.598 1.00 388.94 ? 701 NAG A O4  1 
HETATM 10546 O O5  . NAG E 5 .   ? 111.138 77.138  151.148 1.00 247.89 ? 701 NAG A O5  1 
HETATM 10547 O O6  . NAG E 5 .   ? 111.341 74.937  152.999 1.00 359.83 ? 701 NAG A O6  1 
HETATM 10548 O O7  . NAG E 5 .   ? 107.545 79.848  150.561 1.00 365.08 ? 701 NAG A O7  1 
HETATM 10549 C C1  . NAG F 5 .   ? 82.222  94.132  138.461 1.00 304.24 ? 702 NAG A C1  1 
HETATM 10550 C C2  . NAG F 5 .   ? 83.190  95.102  139.140 1.00 312.30 ? 702 NAG A C2  1 
HETATM 10551 C C3  . NAG F 5 .   ? 82.760  95.405  140.585 1.00 366.98 ? 702 NAG A C3  1 
HETATM 10552 C C4  . NAG F 5 .   ? 81.269  95.723  140.700 1.00 380.86 ? 702 NAG A C4  1 
HETATM 10553 C C5  . NAG F 5 .   ? 80.445  94.647  139.994 1.00 385.91 ? 702 NAG A C5  1 
HETATM 10554 C C6  . NAG F 5 .   ? 78.953  94.918  140.002 1.00 412.20 ? 702 NAG A C6  1 
HETATM 10555 C C7  . NAG F 5 .   ? 85.040  93.436  139.499 1.00 355.55 ? 702 NAG A C7  1 
HETATM 10556 C C8  . NAG F 5 .   ? 86.317  92.944  138.874 1.00 308.04 ? 702 NAG A C8  1 
HETATM 10557 N N2  . NAG F 5 .   ? 84.575  94.641  139.101 1.00 355.91 ? 702 NAG A N2  1 
HETATM 10558 O O3  . NAG F 5 .   ? 83.522  96.491  141.105 1.00 404.35 ? 702 NAG A O3  1 
HETATM 10559 O O4  . NAG F 5 .   ? 80.909  95.768  142.081 1.00 349.97 ? 702 NAG A O4  1 
HETATM 10560 O O5  . NAG F 5 .   ? 80.869  94.563  138.614 1.00 342.24 ? 702 NAG A O5  1 
HETATM 10561 O O6  . NAG F 5 .   ? 78.629  96.170  139.394 1.00 449.48 ? 702 NAG A O6  1 
HETATM 10562 O O7  . NAG F 5 .   ? 84.428  92.754  140.314 1.00 374.41 ? 702 NAG A O7  1 
HETATM 10563 C C1  . NAG G 5 .   ? 125.722 66.897  128.318 1.00 374.56 ? 703 NAG A C1  1 
HETATM 10564 C C2  . NAG G 5 .   ? 126.831 65.856  128.278 1.00 410.64 ? 703 NAG A C2  1 
HETATM 10565 C C3  . NAG G 5 .   ? 128.119 66.534  127.811 1.00 493.79 ? 703 NAG A C3  1 
HETATM 10566 C C4  . NAG G 5 .   ? 127.913 67.223  126.465 1.00 533.65 ? 703 NAG A C4  1 
HETATM 10567 C C5  . NAG G 5 .   ? 126.689 68.148  126.500 1.00 538.18 ? 703 NAG A C5  1 
HETATM 10568 C C6  . NAG G 5 .   ? 126.292 68.669  125.130 1.00 594.84 ? 703 NAG A C6  1 
HETATM 10569 C C7  . NAG G 5 .   ? 126.312 64.111  129.949 1.00 405.70 ? 703 NAG A C7  1 
HETATM 10570 C C8  . NAG G 5 .   ? 126.735 63.464  131.236 1.00 396.94 ? 703 NAG A C8  1 
HETATM 10571 N N2  . NAG G 5 .   ? 127.007 65.190  129.556 1.00 409.43 ? 703 NAG A N2  1 
HETATM 10572 O O3  . NAG G 5 .   ? 129.186 65.593  127.734 1.00 528.60 ? 703 NAG A O3  1 
HETATM 10573 O O4  . NAG G 5 .   ? 129.092 67.975  126.179 1.00 557.17 ? 703 NAG A O4  1 
HETATM 10574 O O5  . NAG G 5 .   ? 125.535 67.446  127.015 1.00 421.38 ? 703 NAG A O5  1 
HETATM 10575 O O6  . NAG G 5 .   ? 125.209 69.607  125.193 1.00 596.52 ? 703 NAG A O6  1 
HETATM 10576 O O7  . NAG G 5 .   ? 125.370 63.676  129.293 1.00 408.82 ? 703 NAG A O7  1 
HETATM 10577 C C1  . NAG H 5 .   ? 125.384 96.184  136.270 1.00 336.84 ? 704 NAG A C1  1 
HETATM 10578 C C2  . NAG H 5 .   ? 126.646 95.532  135.700 1.00 452.51 ? 704 NAG A C2  1 
HETATM 10579 C C3  . NAG H 5 .   ? 127.844 96.470  135.890 1.00 518.78 ? 704 NAG A C3  1 
HETATM 10580 C C4  . NAG H 5 .   ? 127.539 97.847  135.302 1.00 485.82 ? 704 NAG A C4  1 
HETATM 10581 C C5  . NAG H 5 .   ? 126.262 98.407  135.930 1.00 391.53 ? 704 NAG A C5  1 
HETATM 10582 C C6  . NAG H 5 .   ? 125.826 99.734  135.344 1.00 405.26 ? 704 NAG A C6  1 
HETATM 10583 C C7  . NAG H 5 .   ? 127.031 93.828  137.492 1.00 401.78 ? 704 NAG A C7  1 
HETATM 10584 C C8  . NAG H 5 .   ? 127.141 92.358  137.773 1.00 354.28 ? 704 NAG A C8  1 
HETATM 10585 N N2  . NAG H 5 .   ? 126.891 94.187  136.202 1.00 444.51 ? 704 NAG A N2  1 
HETATM 10586 O O3  . NAG H 5 .   ? 129.017 95.924  135.297 1.00 564.20 ? 704 NAG A O3  1 
HETATM 10587 O O4  . NAG H 5 .   ? 128.635 98.723  135.561 1.00 512.09 ? 704 NAG A O4  1 
HETATM 10588 O O5  . NAG H 5 .   ? 125.183 97.477  135.699 1.00 321.44 ? 704 NAG A O5  1 
HETATM 10589 O O6  . NAG H 5 .   ? 126.791 100.763 135.577 1.00 466.29 ? 704 NAG A O6  1 
HETATM 10590 O O7  . NAG H 5 .   ? 127.058 94.650  138.403 1.00 386.96 ? 704 NAG A O7  1 
HETATM 10591 N N1  . VU0 I 6 .   ? 99.704  92.600  84.417  1.00 218.21 ? 601 VU0 B N1  1 
HETATM 10592 C C1  . VU0 I 6 .   ? 100.237 93.625  85.381  1.00 179.93 ? 601 VU0 B C1  1 
HETATM 10593 C C2  . VU0 I 6 .   ? 99.137  94.580  85.917  1.00 152.70 ? 601 VU0 B C2  1 
HETATM 10594 C C3  . VU0 I 6 .   ? 99.525  95.958  85.394  1.00 168.02 ? 601 VU0 B C3  1 
HETATM 10595 C C4  . VU0 I 6 .   ? 99.393  95.989  83.850  1.00 235.69 ? 601 VU0 B C4  1 
HETATM 10596 C C5  . VU0 I 6 .   ? 100.685 95.268  83.371  1.00 242.23 ? 601 VU0 B C5  1 
HETATM 10597 C C6  . VU0 I 6 .   ? 101.219 94.674  84.688  1.00 217.98 ? 601 VU0 B C6  1 
HETATM 10598 C C7  . VU0 I 6 .   ? 101.033 95.911  85.576  1.00 226.51 ? 601 VU0 B C7  1 
HETATM 10599 C C8  . VU0 I 6 .   ? 100.825 92.778  86.544  1.00 168.73 ? 601 VU0 B C8  1 
HETATM 10600 O O1  . VU0 I 6 .   ? 100.163 91.924  87.074  1.00 203.89 ? 601 VU0 B O1  1 
HETATM 10601 O O2  . VU0 I 6 .   ? 101.935 92.962  86.920  1.00 231.83 ? 601 VU0 B O2  1 
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