data_8KDD
# 
_entry.id   8KDD 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8KDD         pdb_00008kdd 10.2210/pdb8kdd/pdb 
WWPDB D_1300040153 ?            ?                   
EMDB  EMD-37132    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1  'Structure model' 1 0 2025-02-12 ? 
2  'EM metadata'     1 0 2025-02-12 ? 
3  FSC               1 0 2025-02-12 ? 
4  'Half map'        1 0 2025-02-12 1 
5  'Half map'        1 0 2025-02-12 2 
6  Image             1 0 2025-02-12 ? 
7  Mask              1 0 2025-02-12 ? 
8  'Primary map'     1 0 2025-02-12 ? 
9  'Structure model' 1 1 2025-02-26 ? 
10 'EM metadata'     1 1 2025-02-26 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 Mask              repository 'Initial release' ? ? 
8 8 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 9  'Structure model' 'Data collection'      
2 9  'Structure model' 'Database references'  
3 10 'EM metadata'     'Database references'  
4 10 'EM metadata'     'Experimental summary' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 9  'Structure model' citation        
2 9  'Structure model' citation_author 
3 9  'Structure model' em_admin        
4 10 'EM metadata'     citation        
5 10 'EM metadata'     citation_author 
6 10 'EM metadata'     em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  9  'Structure model' '_citation.country'                 
2  9  'Structure model' '_citation.journal_abbrev'          
3  9  'Structure model' '_citation.journal_id_CSD'          
4  9  'Structure model' '_citation.journal_id_ISSN'         
5  9  'Structure model' '_citation.journal_volume'          
6  9  'Structure model' '_citation.page_first'              
7  9  'Structure model' '_citation.page_last'               
8  9  'Structure model' '_citation.pdbx_database_id_DOI'    
9  9  'Structure model' '_citation.pdbx_database_id_PubMed' 
10 9  'Structure model' '_citation.title'                   
11 9  'Structure model' '_citation.year'                    
12 9  'Structure model' '_em_admin.last_update'             
13 10 'EM metadata'     '_citation.country'                 
14 10 'EM metadata'     '_citation.journal_abbrev'          
15 10 'EM metadata'     '_citation.journal_id_CSD'          
16 10 'EM metadata'     '_citation.journal_id_ISSN'         
17 10 'EM metadata'     '_citation.journal_volume'          
18 10 'EM metadata'     '_citation.page_first'              
19 10 'EM metadata'     '_citation.page_last'               
20 10 'EM metadata'     '_citation.pdbx_database_id_DOI'    
21 10 'EM metadata'     '_citation.pdbx_database_id_PubMed' 
22 10 'EM metadata'     '_citation.title'                   
23 10 'EM metadata'     '_citation.year'                    
24 10 'EM metadata'     '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8KDD 
_pdbx_database_status.recvd_initial_deposition_date   2023-08-09 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'Structure of LAT1-CD98hc-Fab170 in complex with JPH203, consensus map' EMD-37132 'associated EM volume' 
EMDB 'Structure of LAT1-CD98hc in complex with JPH203, focused on TMD'       EMD-37134 'focused EM volume'    
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              ri.yon.df@yokohama-cu.ac.jp 
_pdbx_contact_author.name_first         Yongchan 
_pdbx_contact_author.name_last          Lee 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1507-805X 
# 
_audit_author.name               'Lee, Y.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                1635 
_citation.page_last                 1635 
_citation.title                     'Structural basis of anticancer drug recognition and amino acid transport by LAT1.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-56903-w 
_citation.pdbx_database_id_PubMed   39952931 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Lee, Y.'          1  0000-0002-1507-805X 
primary 'Jin, C.'          2  ?                   
primary 'Ohgaki, R.'       3  0000-0002-6894-7239 
primary 'Xu, M.'           4  ?                   
primary 'Ogasawara, S.'    5  0000-0001-6908-9953 
primary 'Warshamanage, R.' 6  ?                   
primary 'Yamashita, K.'    7  0000-0002-5442-7582 
primary 'Murshudov, G.'    8  ?                   
primary 'Nureki, O.'       9  0000-0003-1813-7008 
primary 'Murata, T.'       10 0000-0002-5748-4670 
primary 'Kanai, Y.'        11 0000-0001-8126-286X 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man '4F2 cell-surface antigen heavy chain'                  68069.625 1 ? ? ? ? 
2 polymer     man 'Large neutral amino acids transporter small subunit 1' 56043.746 1 ? ? ? ? 
3 polymer     nat 'Fab170 light chain'                                    24355.986 1 ? ? ? ? 
4 polymer     nat 'Fab170 heavy chain'                                    24981.906 1 ? ? ? ? 
5 non-polymer syn 2-acetamido-2-deoxy-beta-D-glucopyranose                221.208   4 ? ? ? ? 
6 non-polymer syn Nanvuranlat                                             472.321   1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Glycoprotein, 4F2hc,4F2 heavy chain antigen,Lymphocyte activation antigen 4F2 large subunit,Solute carrier family 3 member 2' 
2 
;4F2 light chain,4F2LC,CD98 light chain,Integral membrane protein E16,L-type amino acid transporter 1,hLAT1,Solute carrier family 7 member 5,y+ system cationic amino acid transporter
;
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;GSELQPPEASIAVVSIPRQLPGSHSEAGVQGLSAGDDSELGSHCVAQTGLELLASGDPLPSASQNAEMIETGSDCVTQAG
LQLLASSDPPALASKNAEVTGTMSQDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEKNGLVKIKVAEDEAEAAAAA
KFTGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAG
NLAGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWF
STQVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQILSLLESNKDLL
LTSSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAAL
PGQPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQ
NERFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPYAA
;
;GSELQPPEASIAVVSIPRQLPGSHSEAGVQGLSAGDDSELGSHCVAQTGLELLASGDPLPSASQNAEMIETGSDCVTQAG
LQLLASSDPPALASKNAEVTGTMSQDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEKNGLVKIKVAEDEAEAAAAA
KFTGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAG
NLAGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWF
STQVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQILSLLESNKDLL
LTSSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAAL
PGQPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQ
NERFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPYAA
;
A ? 
2 'polypeptide(L)' no no 
;MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAG
SPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPL
FPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV
GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHL
GVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFF
SFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN
KPKWLLQGIFSTTVLCQKLMQVVPQETDYKDDDDK
;
;MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAG
SPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPL
FPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV
GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHL
GVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFF
SFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN
KPKWLLQGIFSTTVLCQKLMQVVPQETDYKDDDDK
;
B ? 
3 'polypeptide(L)' no no 
;DIVLTQSPSSLAMSVGQKVTMNCKSSQSLLNNNNQKNYLAWYQQKPGQSPKLLVYFTSTRESGVPDRFIGSGSGTDFTLT
ISSVQAEDLALYYCQQHYTIPPTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSE
RQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC
;
;DIVLTQSPSSLAMSVGQKVTMNCKSSQSLLNNNNQKNYLAWYQQKPGQSPKLLVYFTSTRESGVPDRFIGSGSGTDFTLT
ISSVQAEDLALYYCQQHYTIPPTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSE
RQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC
;
L ? 
4 'polypeptide(L)' no no 
;EVQLQQSGAELVKPGASVNLSCKASGYTFTNYWMHWVRLRPGQGLEWIGEIDPSDSYSYYSQNFKGKATLTVDQSSNTAY
LQLTSLTSEDSAVYYCARGRQTYYPWFPYWGQGTLVTVSAAKTTPPSDYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVT
WNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRDCGCKPCICT
;
;EVQLQQSGAELVKPGASVNLSCKASGYTFTNYWMHWVRLRPGQGLEWIGEIDPSDSYSYYSQNFKGKATLTVDQSSNTAY
LQLTSLTSEDSAVYYCARGRQTYYPWFPYWGQGTLVTVSAAKTTPPSDYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVT
WNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRDCGCKPCICT
;
H ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
5 2-acetamido-2-deoxy-beta-D-glucopyranose NAG 
6 Nanvuranlat                              VRW 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   SER n 
1 3   GLU n 
1 4   LEU n 
1 5   GLN n 
1 6   PRO n 
1 7   PRO n 
1 8   GLU n 
1 9   ALA n 
1 10  SER n 
1 11  ILE n 
1 12  ALA n 
1 13  VAL n 
1 14  VAL n 
1 15  SER n 
1 16  ILE n 
1 17  PRO n 
1 18  ARG n 
1 19  GLN n 
1 20  LEU n 
1 21  PRO n 
1 22  GLY n 
1 23  SER n 
1 24  HIS n 
1 25  SER n 
1 26  GLU n 
1 27  ALA n 
1 28  GLY n 
1 29  VAL n 
1 30  GLN n 
1 31  GLY n 
1 32  LEU n 
1 33  SER n 
1 34  ALA n 
1 35  GLY n 
1 36  ASP n 
1 37  ASP n 
1 38  SER n 
1 39  GLU n 
1 40  LEU n 
1 41  GLY n 
1 42  SER n 
1 43  HIS n 
1 44  CYS n 
1 45  VAL n 
1 46  ALA n 
1 47  GLN n 
1 48  THR n 
1 49  GLY n 
1 50  LEU n 
1 51  GLU n 
1 52  LEU n 
1 53  LEU n 
1 54  ALA n 
1 55  SER n 
1 56  GLY n 
1 57  ASP n 
1 58  PRO n 
1 59  LEU n 
1 60  PRO n 
1 61  SER n 
1 62  ALA n 
1 63  SER n 
1 64  GLN n 
1 65  ASN n 
1 66  ALA n 
1 67  GLU n 
1 68  MET n 
1 69  ILE n 
1 70  GLU n 
1 71  THR n 
1 72  GLY n 
1 73  SER n 
1 74  ASP n 
1 75  CYS n 
1 76  VAL n 
1 77  THR n 
1 78  GLN n 
1 79  ALA n 
1 80  GLY n 
1 81  LEU n 
1 82  GLN n 
1 83  LEU n 
1 84  LEU n 
1 85  ALA n 
1 86  SER n 
1 87  SER n 
1 88  ASP n 
1 89  PRO n 
1 90  PRO n 
1 91  ALA n 
1 92  LEU n 
1 93  ALA n 
1 94  SER n 
1 95  LYS n 
1 96  ASN n 
1 97  ALA n 
1 98  GLU n 
1 99  VAL n 
1 100 THR n 
1 101 GLY n 
1 102 THR n 
1 103 MET n 
1 104 SER n 
1 105 GLN n 
1 106 ASP n 
1 107 THR n 
1 108 GLU n 
1 109 VAL n 
1 110 ASP n 
1 111 MET n 
1 112 LYS n 
1 113 GLU n 
1 114 VAL n 
1 115 GLU n 
1 116 LEU n 
1 117 ASN n 
1 118 GLU n 
1 119 LEU n 
1 120 GLU n 
1 121 PRO n 
1 122 GLU n 
1 123 LYS n 
1 124 GLN n 
1 125 PRO n 
1 126 MET n 
1 127 ASN n 
1 128 ALA n 
1 129 ALA n 
1 130 SER n 
1 131 GLY n 
1 132 ALA n 
1 133 ALA n 
1 134 MET n 
1 135 SER n 
1 136 LEU n 
1 137 ALA n 
1 138 GLY n 
1 139 ALA n 
1 140 GLU n 
1 141 LYS n 
1 142 ASN n 
1 143 GLY n 
1 144 LEU n 
1 145 VAL n 
1 146 LYS n 
1 147 ILE n 
1 148 LYS n 
1 149 VAL n 
1 150 ALA n 
1 151 GLU n 
1 152 ASP n 
1 153 GLU n 
1 154 ALA n 
1 155 GLU n 
1 156 ALA n 
1 157 ALA n 
1 158 ALA n 
1 159 ALA n 
1 160 ALA n 
1 161 LYS n 
1 162 PHE n 
1 163 THR n 
1 164 GLY n 
1 165 LEU n 
1 166 SER n 
1 167 LYS n 
1 168 GLU n 
1 169 GLU n 
1 170 LEU n 
1 171 LEU n 
1 172 LYS n 
1 173 VAL n 
1 174 ALA n 
1 175 GLY n 
1 176 SER n 
1 177 PRO n 
1 178 GLY n 
1 179 TRP n 
1 180 VAL n 
1 181 ARG n 
1 182 THR n 
1 183 ARG n 
1 184 TRP n 
1 185 ALA n 
1 186 LEU n 
1 187 LEU n 
1 188 LEU n 
1 189 LEU n 
1 190 PHE n 
1 191 TRP n 
1 192 LEU n 
1 193 GLY n 
1 194 TRP n 
1 195 LEU n 
1 196 GLY n 
1 197 MET n 
1 198 LEU n 
1 199 ALA n 
1 200 GLY n 
1 201 ALA n 
1 202 VAL n 
1 203 VAL n 
1 204 ILE n 
1 205 ILE n 
1 206 VAL n 
1 207 ARG n 
1 208 ALA n 
1 209 PRO n 
1 210 ARG n 
1 211 CYS n 
1 212 ARG n 
1 213 GLU n 
1 214 LEU n 
1 215 PRO n 
1 216 ALA n 
1 217 GLN n 
1 218 LYS n 
1 219 TRP n 
1 220 TRP n 
1 221 HIS n 
1 222 THR n 
1 223 GLY n 
1 224 ALA n 
1 225 LEU n 
1 226 TYR n 
1 227 ARG n 
1 228 ILE n 
1 229 GLY n 
1 230 ASP n 
1 231 LEU n 
1 232 GLN n 
1 233 ALA n 
1 234 PHE n 
1 235 GLN n 
1 236 GLY n 
1 237 HIS n 
1 238 GLY n 
1 239 ALA n 
1 240 GLY n 
1 241 ASN n 
1 242 LEU n 
1 243 ALA n 
1 244 GLY n 
1 245 LEU n 
1 246 LYS n 
1 247 GLY n 
1 248 ARG n 
1 249 LEU n 
1 250 ASP n 
1 251 TYR n 
1 252 LEU n 
1 253 SER n 
1 254 SER n 
1 255 LEU n 
1 256 LYS n 
1 257 VAL n 
1 258 LYS n 
1 259 GLY n 
1 260 LEU n 
1 261 VAL n 
1 262 LEU n 
1 263 GLY n 
1 264 PRO n 
1 265 ILE n 
1 266 HIS n 
1 267 LYS n 
1 268 ASN n 
1 269 GLN n 
1 270 LYS n 
1 271 ASP n 
1 272 ASP n 
1 273 VAL n 
1 274 ALA n 
1 275 GLN n 
1 276 THR n 
1 277 ASP n 
1 278 LEU n 
1 279 LEU n 
1 280 GLN n 
1 281 ILE n 
1 282 ASP n 
1 283 PRO n 
1 284 ASN n 
1 285 PHE n 
1 286 GLY n 
1 287 SER n 
1 288 LYS n 
1 289 GLU n 
1 290 ASP n 
1 291 PHE n 
1 292 ASP n 
1 293 SER n 
1 294 LEU n 
1 295 LEU n 
1 296 GLN n 
1 297 SER n 
1 298 ALA n 
1 299 LYS n 
1 300 LYS n 
1 301 LYS n 
1 302 SER n 
1 303 ILE n 
1 304 ARG n 
1 305 VAL n 
1 306 ILE n 
1 307 LEU n 
1 308 ASP n 
1 309 LEU n 
1 310 THR n 
1 311 PRO n 
1 312 ASN n 
1 313 TYR n 
1 314 ARG n 
1 315 GLY n 
1 316 GLU n 
1 317 ASN n 
1 318 SER n 
1 319 TRP n 
1 320 PHE n 
1 321 SER n 
1 322 THR n 
1 323 GLN n 
1 324 VAL n 
1 325 ASP n 
1 326 THR n 
1 327 VAL n 
1 328 ALA n 
1 329 THR n 
1 330 LYS n 
1 331 VAL n 
1 332 LYS n 
1 333 ASP n 
1 334 ALA n 
1 335 LEU n 
1 336 GLU n 
1 337 PHE n 
1 338 TRP n 
1 339 LEU n 
1 340 GLN n 
1 341 ALA n 
1 342 GLY n 
1 343 VAL n 
1 344 ASP n 
1 345 GLY n 
1 346 PHE n 
1 347 GLN n 
1 348 VAL n 
1 349 ARG n 
1 350 ASP n 
1 351 ILE n 
1 352 GLU n 
1 353 ASN n 
1 354 LEU n 
1 355 LYS n 
1 356 ASP n 
1 357 ALA n 
1 358 SER n 
1 359 SER n 
1 360 PHE n 
1 361 LEU n 
1 362 ALA n 
1 363 GLU n 
1 364 TRP n 
1 365 GLN n 
1 366 ASN n 
1 367 ILE n 
1 368 THR n 
1 369 LYS n 
1 370 GLY n 
1 371 PHE n 
1 372 SER n 
1 373 GLU n 
1 374 ASP n 
1 375 ARG n 
1 376 LEU n 
1 377 LEU n 
1 378 ILE n 
1 379 ALA n 
1 380 GLY n 
1 381 THR n 
1 382 ASN n 
1 383 SER n 
1 384 SER n 
1 385 ASP n 
1 386 LEU n 
1 387 GLN n 
1 388 GLN n 
1 389 ILE n 
1 390 LEU n 
1 391 SER n 
1 392 LEU n 
1 393 LEU n 
1 394 GLU n 
1 395 SER n 
1 396 ASN n 
1 397 LYS n 
1 398 ASP n 
1 399 LEU n 
1 400 LEU n 
1 401 LEU n 
1 402 THR n 
1 403 SER n 
1 404 SER n 
1 405 TYR n 
1 406 LEU n 
1 407 SER n 
1 408 ASP n 
1 409 SER n 
1 410 GLY n 
1 411 SER n 
1 412 THR n 
1 413 GLY n 
1 414 GLU n 
1 415 HIS n 
1 416 THR n 
1 417 LYS n 
1 418 SER n 
1 419 LEU n 
1 420 VAL n 
1 421 THR n 
1 422 GLN n 
1 423 TYR n 
1 424 LEU n 
1 425 ASN n 
1 426 ALA n 
1 427 THR n 
1 428 GLY n 
1 429 ASN n 
1 430 ARG n 
1 431 TRP n 
1 432 CYS n 
1 433 SER n 
1 434 TRP n 
1 435 SER n 
1 436 LEU n 
1 437 SER n 
1 438 GLN n 
1 439 ALA n 
1 440 ARG n 
1 441 LEU n 
1 442 LEU n 
1 443 THR n 
1 444 SER n 
1 445 PHE n 
1 446 LEU n 
1 447 PRO n 
1 448 ALA n 
1 449 GLN n 
1 450 LEU n 
1 451 LEU n 
1 452 ARG n 
1 453 LEU n 
1 454 TYR n 
1 455 GLN n 
1 456 LEU n 
1 457 MET n 
1 458 LEU n 
1 459 PHE n 
1 460 THR n 
1 461 LEU n 
1 462 PRO n 
1 463 GLY n 
1 464 THR n 
1 465 PRO n 
1 466 VAL n 
1 467 PHE n 
1 468 SER n 
1 469 TYR n 
1 470 GLY n 
1 471 ASP n 
1 472 GLU n 
1 473 ILE n 
1 474 GLY n 
1 475 LEU n 
1 476 ASP n 
1 477 ALA n 
1 478 ALA n 
1 479 ALA n 
1 480 LEU n 
1 481 PRO n 
1 482 GLY n 
1 483 GLN n 
1 484 PRO n 
1 485 MET n 
1 486 GLU n 
1 487 ALA n 
1 488 PRO n 
1 489 VAL n 
1 490 MET n 
1 491 LEU n 
1 492 TRP n 
1 493 ASP n 
1 494 GLU n 
1 495 SER n 
1 496 SER n 
1 497 PHE n 
1 498 PRO n 
1 499 ASP n 
1 500 ILE n 
1 501 PRO n 
1 502 GLY n 
1 503 ALA n 
1 504 VAL n 
1 505 SER n 
1 506 ALA n 
1 507 ASN n 
1 508 MET n 
1 509 THR n 
1 510 VAL n 
1 511 LYS n 
1 512 GLY n 
1 513 GLN n 
1 514 SER n 
1 515 GLU n 
1 516 ASP n 
1 517 PRO n 
1 518 GLY n 
1 519 SER n 
1 520 LEU n 
1 521 LEU n 
1 522 SER n 
1 523 LEU n 
1 524 PHE n 
1 525 ARG n 
1 526 ARG n 
1 527 LEU n 
1 528 SER n 
1 529 ASP n 
1 530 GLN n 
1 531 ARG n 
1 532 SER n 
1 533 LYS n 
1 534 GLU n 
1 535 ARG n 
1 536 SER n 
1 537 LEU n 
1 538 LEU n 
1 539 HIS n 
1 540 GLY n 
1 541 ASP n 
1 542 PHE n 
1 543 HIS n 
1 544 ALA n 
1 545 PHE n 
1 546 SER n 
1 547 ALA n 
1 548 GLY n 
1 549 PRO n 
1 550 GLY n 
1 551 LEU n 
1 552 PHE n 
1 553 SER n 
1 554 TYR n 
1 555 ILE n 
1 556 ARG n 
1 557 HIS n 
1 558 TRP n 
1 559 ASP n 
1 560 GLN n 
1 561 ASN n 
1 562 GLU n 
1 563 ARG n 
1 564 PHE n 
1 565 LEU n 
1 566 VAL n 
1 567 VAL n 
1 568 LEU n 
1 569 ASN n 
1 570 PHE n 
1 571 GLY n 
1 572 ASP n 
1 573 VAL n 
1 574 GLY n 
1 575 LEU n 
1 576 SER n 
1 577 ALA n 
1 578 GLY n 
1 579 LEU n 
1 580 GLN n 
1 581 ALA n 
1 582 SER n 
1 583 ASP n 
1 584 LEU n 
1 585 PRO n 
1 586 ALA n 
1 587 SER n 
1 588 ALA n 
1 589 SER n 
1 590 LEU n 
1 591 PRO n 
1 592 ALA n 
1 593 LYS n 
1 594 ALA n 
1 595 ASP n 
1 596 LEU n 
1 597 LEU n 
1 598 LEU n 
1 599 SER n 
1 600 THR n 
1 601 GLN n 
1 602 PRO n 
1 603 GLY n 
1 604 ARG n 
1 605 GLU n 
1 606 GLU n 
1 607 GLY n 
1 608 SER n 
1 609 PRO n 
1 610 LEU n 
1 611 GLU n 
1 612 LEU n 
1 613 GLU n 
1 614 ARG n 
1 615 LEU n 
1 616 LYS n 
1 617 LEU n 
1 618 GLU n 
1 619 PRO n 
1 620 HIS n 
1 621 GLU n 
1 622 GLY n 
1 623 LEU n 
1 624 LEU n 
1 625 LEU n 
1 626 ARG n 
1 627 PHE n 
1 628 PRO n 
1 629 TYR n 
1 630 ALA n 
1 631 ALA n 
2 1   MET n 
2 2   ALA n 
2 3   GLY n 
2 4   ALA n 
2 5   GLY n 
2 6   PRO n 
2 7   LYS n 
2 8   ARG n 
2 9   ARG n 
2 10  ALA n 
2 11  LEU n 
2 12  ALA n 
2 13  ALA n 
2 14  PRO n 
2 15  ALA n 
2 16  ALA n 
2 17  GLU n 
2 18  GLU n 
2 19  LYS n 
2 20  GLU n 
2 21  GLU n 
2 22  ALA n 
2 23  ARG n 
2 24  GLU n 
2 25  LYS n 
2 26  MET n 
2 27  LEU n 
2 28  ALA n 
2 29  ALA n 
2 30  LYS n 
2 31  SER n 
2 32  ALA n 
2 33  ASP n 
2 34  GLY n 
2 35  SER n 
2 36  ALA n 
2 37  PRO n 
2 38  ALA n 
2 39  GLY n 
2 40  GLU n 
2 41  GLY n 
2 42  GLU n 
2 43  GLY n 
2 44  VAL n 
2 45  THR n 
2 46  LEU n 
2 47  GLN n 
2 48  ARG n 
2 49  ASN n 
2 50  ILE n 
2 51  THR n 
2 52  LEU n 
2 53  LEU n 
2 54  ASN n 
2 55  GLY n 
2 56  VAL n 
2 57  ALA n 
2 58  ILE n 
2 59  ILE n 
2 60  VAL n 
2 61  GLY n 
2 62  THR n 
2 63  ILE n 
2 64  ILE n 
2 65  GLY n 
2 66  SER n 
2 67  GLY n 
2 68  ILE n 
2 69  PHE n 
2 70  VAL n 
2 71  THR n 
2 72  PRO n 
2 73  THR n 
2 74  GLY n 
2 75  VAL n 
2 76  LEU n 
2 77  LYS n 
2 78  GLU n 
2 79  ALA n 
2 80  GLY n 
2 81  SER n 
2 82  PRO n 
2 83  GLY n 
2 84  LEU n 
2 85  ALA n 
2 86  LEU n 
2 87  VAL n 
2 88  VAL n 
2 89  TRP n 
2 90  ALA n 
2 91  ALA n 
2 92  CYS n 
2 93  GLY n 
2 94  VAL n 
2 95  PHE n 
2 96  SER n 
2 97  ILE n 
2 98  VAL n 
2 99  GLY n 
2 100 ALA n 
2 101 LEU n 
2 102 CYS n 
2 103 TYR n 
2 104 ALA n 
2 105 GLU n 
2 106 LEU n 
2 107 GLY n 
2 108 THR n 
2 109 THR n 
2 110 ILE n 
2 111 SER n 
2 112 LYS n 
2 113 SER n 
2 114 GLY n 
2 115 GLY n 
2 116 ASP n 
2 117 TYR n 
2 118 ALA n 
2 119 TYR n 
2 120 MET n 
2 121 LEU n 
2 122 GLU n 
2 123 VAL n 
2 124 TYR n 
2 125 GLY n 
2 126 SER n 
2 127 LEU n 
2 128 PRO n 
2 129 ALA n 
2 130 PHE n 
2 131 LEU n 
2 132 LYS n 
2 133 LEU n 
2 134 TRP n 
2 135 ILE n 
2 136 GLU n 
2 137 LEU n 
2 138 LEU n 
2 139 ILE n 
2 140 ILE n 
2 141 ARG n 
2 142 PRO n 
2 143 SER n 
2 144 SER n 
2 145 GLN n 
2 146 TYR n 
2 147 ILE n 
2 148 VAL n 
2 149 ALA n 
2 150 LEU n 
2 151 VAL n 
2 152 PHE n 
2 153 ALA n 
2 154 THR n 
2 155 TYR n 
2 156 LEU n 
2 157 LEU n 
2 158 LYS n 
2 159 PRO n 
2 160 LEU n 
2 161 PHE n 
2 162 PRO n 
2 163 THR n 
2 164 CYS n 
2 165 PRO n 
2 166 VAL n 
2 167 PRO n 
2 168 GLU n 
2 169 GLU n 
2 170 ALA n 
2 171 ALA n 
2 172 LYS n 
2 173 LEU n 
2 174 VAL n 
2 175 ALA n 
2 176 CYS n 
2 177 LEU n 
2 178 CYS n 
2 179 VAL n 
2 180 LEU n 
2 181 LEU n 
2 182 LEU n 
2 183 THR n 
2 184 ALA n 
2 185 VAL n 
2 186 ASN n 
2 187 CYS n 
2 188 TYR n 
2 189 SER n 
2 190 VAL n 
2 191 LYS n 
2 192 ALA n 
2 193 ALA n 
2 194 THR n 
2 195 ARG n 
2 196 VAL n 
2 197 GLN n 
2 198 ASP n 
2 199 ALA n 
2 200 PHE n 
2 201 ALA n 
2 202 ALA n 
2 203 ALA n 
2 204 LYS n 
2 205 LEU n 
2 206 LEU n 
2 207 ALA n 
2 208 LEU n 
2 209 ALA n 
2 210 LEU n 
2 211 ILE n 
2 212 ILE n 
2 213 LEU n 
2 214 LEU n 
2 215 GLY n 
2 216 PHE n 
2 217 VAL n 
2 218 GLN n 
2 219 ILE n 
2 220 GLY n 
2 221 LYS n 
2 222 GLY n 
2 223 ASP n 
2 224 VAL n 
2 225 SER n 
2 226 ASN n 
2 227 LEU n 
2 228 ASP n 
2 229 PRO n 
2 230 ASN n 
2 231 PHE n 
2 232 SER n 
2 233 PHE n 
2 234 GLU n 
2 235 GLY n 
2 236 THR n 
2 237 LYS n 
2 238 LEU n 
2 239 ASP n 
2 240 VAL n 
2 241 GLY n 
2 242 ASN n 
2 243 ILE n 
2 244 VAL n 
2 245 LEU n 
2 246 ALA n 
2 247 LEU n 
2 248 TYR n 
2 249 SER n 
2 250 GLY n 
2 251 LEU n 
2 252 PHE n 
2 253 ALA n 
2 254 TYR n 
2 255 GLY n 
2 256 GLY n 
2 257 TRP n 
2 258 ASN n 
2 259 TYR n 
2 260 LEU n 
2 261 ASN n 
2 262 PHE n 
2 263 VAL n 
2 264 THR n 
2 265 GLU n 
2 266 GLU n 
2 267 MET n 
2 268 ILE n 
2 269 ASN n 
2 270 PRO n 
2 271 TYR n 
2 272 ARG n 
2 273 ASN n 
2 274 LEU n 
2 275 PRO n 
2 276 LEU n 
2 277 ALA n 
2 278 ILE n 
2 279 ILE n 
2 280 ILE n 
2 281 SER n 
2 282 LEU n 
2 283 PRO n 
2 284 ILE n 
2 285 VAL n 
2 286 THR n 
2 287 LEU n 
2 288 VAL n 
2 289 TYR n 
2 290 VAL n 
2 291 LEU n 
2 292 THR n 
2 293 ASN n 
2 294 LEU n 
2 295 ALA n 
2 296 TYR n 
2 297 PHE n 
2 298 THR n 
2 299 THR n 
2 300 LEU n 
2 301 SER n 
2 302 THR n 
2 303 GLU n 
2 304 GLN n 
2 305 MET n 
2 306 LEU n 
2 307 SER n 
2 308 SER n 
2 309 GLU n 
2 310 ALA n 
2 311 VAL n 
2 312 ALA n 
2 313 VAL n 
2 314 ASP n 
2 315 PHE n 
2 316 GLY n 
2 317 ASN n 
2 318 TYR n 
2 319 HIS n 
2 320 LEU n 
2 321 GLY n 
2 322 VAL n 
2 323 MET n 
2 324 SER n 
2 325 TRP n 
2 326 ILE n 
2 327 ILE n 
2 328 PRO n 
2 329 VAL n 
2 330 PHE n 
2 331 VAL n 
2 332 GLY n 
2 333 LEU n 
2 334 SER n 
2 335 CYS n 
2 336 PHE n 
2 337 GLY n 
2 338 SER n 
2 339 VAL n 
2 340 ASN n 
2 341 GLY n 
2 342 SER n 
2 343 LEU n 
2 344 PHE n 
2 345 THR n 
2 346 SER n 
2 347 SER n 
2 348 ARG n 
2 349 LEU n 
2 350 PHE n 
2 351 PHE n 
2 352 VAL n 
2 353 GLY n 
2 354 SER n 
2 355 ARG n 
2 356 GLU n 
2 357 GLY n 
2 358 HIS n 
2 359 LEU n 
2 360 PRO n 
2 361 SER n 
2 362 ILE n 
2 363 LEU n 
2 364 SER n 
2 365 MET n 
2 366 ILE n 
2 367 HIS n 
2 368 PRO n 
2 369 GLN n 
2 370 LEU n 
2 371 LEU n 
2 372 THR n 
2 373 PRO n 
2 374 VAL n 
2 375 PRO n 
2 376 SER n 
2 377 LEU n 
2 378 VAL n 
2 379 PHE n 
2 380 THR n 
2 381 CYS n 
2 382 VAL n 
2 383 MET n 
2 384 THR n 
2 385 LEU n 
2 386 LEU n 
2 387 TYR n 
2 388 ALA n 
2 389 PHE n 
2 390 SER n 
2 391 LYS n 
2 392 ASP n 
2 393 ILE n 
2 394 PHE n 
2 395 SER n 
2 396 VAL n 
2 397 ILE n 
2 398 ASN n 
2 399 PHE n 
2 400 PHE n 
2 401 SER n 
2 402 PHE n 
2 403 PHE n 
2 404 ASN n 
2 405 TRP n 
2 406 LEU n 
2 407 CYS n 
2 408 VAL n 
2 409 ALA n 
2 410 LEU n 
2 411 ALA n 
2 412 ILE n 
2 413 ILE n 
2 414 GLY n 
2 415 MET n 
2 416 ILE n 
2 417 TRP n 
2 418 LEU n 
2 419 ARG n 
2 420 HIS n 
2 421 ARG n 
2 422 LYS n 
2 423 PRO n 
2 424 GLU n 
2 425 LEU n 
2 426 GLU n 
2 427 ARG n 
2 428 PRO n 
2 429 ILE n 
2 430 LYS n 
2 431 VAL n 
2 432 ASN n 
2 433 LEU n 
2 434 ALA n 
2 435 LEU n 
2 436 PRO n 
2 437 VAL n 
2 438 PHE n 
2 439 PHE n 
2 440 ILE n 
2 441 LEU n 
2 442 ALA n 
2 443 CYS n 
2 444 LEU n 
2 445 PHE n 
2 446 LEU n 
2 447 ILE n 
2 448 ALA n 
2 449 VAL n 
2 450 SER n 
2 451 PHE n 
2 452 TRP n 
2 453 LYS n 
2 454 THR n 
2 455 PRO n 
2 456 VAL n 
2 457 GLU n 
2 458 CYS n 
2 459 GLY n 
2 460 ILE n 
2 461 GLY n 
2 462 PHE n 
2 463 THR n 
2 464 ILE n 
2 465 ILE n 
2 466 LEU n 
2 467 SER n 
2 468 GLY n 
2 469 LEU n 
2 470 PRO n 
2 471 VAL n 
2 472 TYR n 
2 473 PHE n 
2 474 PHE n 
2 475 GLY n 
2 476 VAL n 
2 477 TRP n 
2 478 TRP n 
2 479 LYS n 
2 480 ASN n 
2 481 LYS n 
2 482 PRO n 
2 483 LYS n 
2 484 TRP n 
2 485 LEU n 
2 486 LEU n 
2 487 GLN n 
2 488 GLY n 
2 489 ILE n 
2 490 PHE n 
2 491 SER n 
2 492 THR n 
2 493 THR n 
2 494 VAL n 
2 495 LEU n 
2 496 CYS n 
2 497 GLN n 
2 498 LYS n 
2 499 LEU n 
2 500 MET n 
2 501 GLN n 
2 502 VAL n 
2 503 VAL n 
2 504 PRO n 
2 505 GLN n 
2 506 GLU n 
2 507 THR n 
2 508 ASP n 
2 509 TYR n 
2 510 LYS n 
2 511 ASP n 
2 512 ASP n 
2 513 ASP n 
2 514 ASP n 
2 515 LYS n 
3 1   ASP n 
3 2   ILE n 
3 3   VAL n 
3 4   LEU n 
3 5   THR n 
3 6   GLN n 
3 7   SER n 
3 8   PRO n 
3 9   SER n 
3 10  SER n 
3 11  LEU n 
3 12  ALA n 
3 13  MET n 
3 14  SER n 
3 15  VAL n 
3 16  GLY n 
3 17  GLN n 
3 18  LYS n 
3 19  VAL n 
3 20  THR n 
3 21  MET n 
3 22  ASN n 
3 23  CYS n 
3 24  LYS n 
3 25  SER n 
3 26  SER n 
3 27  GLN n 
3 28  SER n 
3 29  LEU n 
3 30  LEU n 
3 31  ASN n 
3 32  ASN n 
3 33  ASN n 
3 34  ASN n 
3 35  GLN n 
3 36  LYS n 
3 37  ASN n 
3 38  TYR n 
3 39  LEU n 
3 40  ALA n 
3 41  TRP n 
3 42  TYR n 
3 43  GLN n 
3 44  GLN n 
3 45  LYS n 
3 46  PRO n 
3 47  GLY n 
3 48  GLN n 
3 49  SER n 
3 50  PRO n 
3 51  LYS n 
3 52  LEU n 
3 53  LEU n 
3 54  VAL n 
3 55  TYR n 
3 56  PHE n 
3 57  THR n 
3 58  SER n 
3 59  THR n 
3 60  ARG n 
3 61  GLU n 
3 62  SER n 
3 63  GLY n 
3 64  VAL n 
3 65  PRO n 
3 66  ASP n 
3 67  ARG n 
3 68  PHE n 
3 69  ILE n 
3 70  GLY n 
3 71  SER n 
3 72  GLY n 
3 73  SER n 
3 74  GLY n 
3 75  THR n 
3 76  ASP n 
3 77  PHE n 
3 78  THR n 
3 79  LEU n 
3 80  THR n 
3 81  ILE n 
3 82  SER n 
3 83  SER n 
3 84  VAL n 
3 85  GLN n 
3 86  ALA n 
3 87  GLU n 
3 88  ASP n 
3 89  LEU n 
3 90  ALA n 
3 91  LEU n 
3 92  TYR n 
3 93  TYR n 
3 94  CYS n 
3 95  GLN n 
3 96  GLN n 
3 97  HIS n 
3 98  TYR n 
3 99  THR n 
3 100 ILE n 
3 101 PRO n 
3 102 PRO n 
3 103 THR n 
3 104 PHE n 
3 105 GLY n 
3 106 GLY n 
3 107 GLY n 
3 108 THR n 
3 109 LYS n 
3 110 LEU n 
3 111 GLU n 
3 112 ILE n 
3 113 LYS n 
3 114 ARG n 
3 115 ALA n 
3 116 ASP n 
3 117 ALA n 
3 118 ALA n 
3 119 PRO n 
3 120 THR n 
3 121 VAL n 
3 122 SER n 
3 123 ILE n 
3 124 PHE n 
3 125 PRO n 
3 126 PRO n 
3 127 SER n 
3 128 SER n 
3 129 GLU n 
3 130 GLN n 
3 131 LEU n 
3 132 THR n 
3 133 SER n 
3 134 GLY n 
3 135 GLY n 
3 136 ALA n 
3 137 SER n 
3 138 VAL n 
3 139 VAL n 
3 140 CYS n 
3 141 PHE n 
3 142 LEU n 
3 143 ASN n 
3 144 ASN n 
3 145 PHE n 
3 146 TYR n 
3 147 PRO n 
3 148 LYS n 
3 149 ASP n 
3 150 ILE n 
3 151 ASN n 
3 152 VAL n 
3 153 LYS n 
3 154 TRP n 
3 155 LYS n 
3 156 ILE n 
3 157 ASP n 
3 158 GLY n 
3 159 SER n 
3 160 GLU n 
3 161 ARG n 
3 162 GLN n 
3 163 ASN n 
3 164 GLY n 
3 165 VAL n 
3 166 LEU n 
3 167 ASN n 
3 168 SER n 
3 169 TRP n 
3 170 THR n 
3 171 ASP n 
3 172 GLN n 
3 173 ASP n 
3 174 SER n 
3 175 LYS n 
3 176 ASP n 
3 177 SER n 
3 178 THR n 
3 179 TYR n 
3 180 SER n 
3 181 MET n 
3 182 SER n 
3 183 SER n 
3 184 THR n 
3 185 LEU n 
3 186 THR n 
3 187 LEU n 
3 188 THR n 
3 189 LYS n 
3 190 ASP n 
3 191 GLU n 
3 192 TYR n 
3 193 GLU n 
3 194 ARG n 
3 195 HIS n 
3 196 ASN n 
3 197 SER n 
3 198 TYR n 
3 199 THR n 
3 200 CYS n 
3 201 GLU n 
3 202 ALA n 
3 203 THR n 
3 204 HIS n 
3 205 LYS n 
3 206 THR n 
3 207 SER n 
3 208 THR n 
3 209 SER n 
3 210 PRO n 
3 211 ILE n 
3 212 VAL n 
3 213 LYS n 
3 214 SER n 
3 215 PHE n 
3 216 ASN n 
3 217 ARG n 
3 218 ASN n 
3 219 GLU n 
3 220 CYS n 
4 1   GLU n 
4 2   VAL n 
4 3   GLN n 
4 4   LEU n 
4 5   GLN n 
4 6   GLN n 
4 7   SER n 
4 8   GLY n 
4 9   ALA n 
4 10  GLU n 
4 11  LEU n 
4 12  VAL n 
4 13  LYS n 
4 14  PRO n 
4 15  GLY n 
4 16  ALA n 
4 17  SER n 
4 18  VAL n 
4 19  ASN n 
4 20  LEU n 
4 21  SER n 
4 22  CYS n 
4 23  LYS n 
4 24  ALA n 
4 25  SER n 
4 26  GLY n 
4 27  TYR n 
4 28  THR n 
4 29  PHE n 
4 30  THR n 
4 31  ASN n 
4 32  TYR n 
4 33  TRP n 
4 34  MET n 
4 35  HIS n 
4 36  TRP n 
4 37  VAL n 
4 38  ARG n 
4 39  LEU n 
4 40  ARG n 
4 41  PRO n 
4 42  GLY n 
4 43  GLN n 
4 44  GLY n 
4 45  LEU n 
4 46  GLU n 
4 47  TRP n 
4 48  ILE n 
4 49  GLY n 
4 50  GLU n 
4 51  ILE n 
4 52  ASP n 
4 53  PRO n 
4 54  SER n 
4 55  ASP n 
4 56  SER n 
4 57  TYR n 
4 58  SER n 
4 59  TYR n 
4 60  TYR n 
4 61  SER n 
4 62  GLN n 
4 63  ASN n 
4 64  PHE n 
4 65  LYS n 
4 66  GLY n 
4 67  LYS n 
4 68  ALA n 
4 69  THR n 
4 70  LEU n 
4 71  THR n 
4 72  VAL n 
4 73  ASP n 
4 74  GLN n 
4 75  SER n 
4 76  SER n 
4 77  ASN n 
4 78  THR n 
4 79  ALA n 
4 80  TYR n 
4 81  LEU n 
4 82  GLN n 
4 83  LEU n 
4 84  THR n 
4 85  SER n 
4 86  LEU n 
4 87  THR n 
4 88  SER n 
4 89  GLU n 
4 90  ASP n 
4 91  SER n 
4 92  ALA n 
4 93  VAL n 
4 94  TYR n 
4 95  TYR n 
4 96  CYS n 
4 97  ALA n 
4 98  ARG n 
4 99  GLY n 
4 100 ARG n 
4 101 GLN n 
4 102 THR n 
4 103 TYR n 
4 104 TYR n 
4 105 PRO n 
4 106 TRP n 
4 107 PHE n 
4 108 PRO n 
4 109 TYR n 
4 110 TRP n 
4 111 GLY n 
4 112 GLN n 
4 113 GLY n 
4 114 THR n 
4 115 LEU n 
4 116 VAL n 
4 117 THR n 
4 118 VAL n 
4 119 SER n 
4 120 ALA n 
4 121 ALA n 
4 122 LYS n 
4 123 THR n 
4 124 THR n 
4 125 PRO n 
4 126 PRO n 
4 127 SER n 
4 128 ASP n 
4 129 TYR n 
4 130 PRO n 
4 131 LEU n 
4 132 ALA n 
4 133 PRO n 
4 134 GLY n 
4 135 SER n 
4 136 ALA n 
4 137 ALA n 
4 138 GLN n 
4 139 THR n 
4 140 ASN n 
4 141 SER n 
4 142 MET n 
4 143 VAL n 
4 144 THR n 
4 145 LEU n 
4 146 GLY n 
4 147 CYS n 
4 148 LEU n 
4 149 VAL n 
4 150 LYS n 
4 151 GLY n 
4 152 TYR n 
4 153 PHE n 
4 154 PRO n 
4 155 GLU n 
4 156 PRO n 
4 157 VAL n 
4 158 THR n 
4 159 VAL n 
4 160 THR n 
4 161 TRP n 
4 162 ASN n 
4 163 SER n 
4 164 GLY n 
4 165 SER n 
4 166 LEU n 
4 167 SER n 
4 168 SER n 
4 169 GLY n 
4 170 VAL n 
4 171 HIS n 
4 172 THR n 
4 173 PHE n 
4 174 PRO n 
4 175 ALA n 
4 176 VAL n 
4 177 LEU n 
4 178 GLN n 
4 179 SER n 
4 180 ASP n 
4 181 LEU n 
4 182 TYR n 
4 183 THR n 
4 184 LEU n 
4 185 SER n 
4 186 SER n 
4 187 SER n 
4 188 VAL n 
4 189 THR n 
4 190 VAL n 
4 191 PRO n 
4 192 SER n 
4 193 SER n 
4 194 THR n 
4 195 TRP n 
4 196 PRO n 
4 197 SER n 
4 198 GLU n 
4 199 THR n 
4 200 VAL n 
4 201 THR n 
4 202 CYS n 
4 203 ASN n 
4 204 VAL n 
4 205 ALA n 
4 206 HIS n 
4 207 PRO n 
4 208 ALA n 
4 209 SER n 
4 210 SER n 
4 211 THR n 
4 212 LYS n 
4 213 VAL n 
4 214 ASP n 
4 215 LYS n 
4 216 LYS n 
4 217 ILE n 
4 218 VAL n 
4 219 PRO n 
4 220 ARG n 
4 221 ASP n 
4 222 CYS n 
4 223 GLY n 
4 224 CYS n 
4 225 LYS n 
4 226 PRO n 
4 227 CYS n 
4 228 ILE n 
4 229 CYS n 
4 230 THR n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 631 human ? 'SLC3A2, MDU1'                ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 515 human ? 'SLC7A5, CD98LC, LAT1, MPE16' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_entity_src_nat.entity_id 
_entity_src_nat.pdbx_src_id 
_entity_src_nat.pdbx_alt_source_flag 
_entity_src_nat.pdbx_beg_seq_num 
_entity_src_nat.pdbx_end_seq_num 
_entity_src_nat.common_name 
_entity_src_nat.pdbx_organism_scientific 
_entity_src_nat.pdbx_ncbi_taxonomy_id 
_entity_src_nat.genus 
_entity_src_nat.species 
_entity_src_nat.strain 
_entity_src_nat.tissue 
_entity_src_nat.tissue_fraction 
_entity_src_nat.pdbx_secretion 
_entity_src_nat.pdbx_fragment 
_entity_src_nat.pdbx_variant 
_entity_src_nat.pdbx_cell_line 
_entity_src_nat.pdbx_atcc 
_entity_src_nat.pdbx_cellular_location 
_entity_src_nat.pdbx_organ 
_entity_src_nat.pdbx_organelle 
_entity_src_nat.pdbx_cell 
_entity_src_nat.pdbx_plasmid_name 
_entity_src_nat.pdbx_plasmid_details 
_entity_src_nat.details 
3 1 sample 1 220 ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 1 230 ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE                                  ? 'C3 H7 N O2'        89.093  
ARG 'L-peptide linking'          y ARGININE                                 ? 'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking'          y ASPARAGINE                               ? 'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'        133.103 
CYS 'L-peptide linking'          y CYSTEINE                                 ? 'C3 H7 N O2 S'      121.158 
GLN 'L-peptide linking'          y GLUTAMINE                                ? 'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'        147.129 
GLY 'peptide linking'            y GLYCINE                                  ? 'C2 H5 N O2'        75.067  
HIS 'L-peptide linking'          y HISTIDINE                                ? 'C6 H10 N3 O2 1'    156.162 
ILE 'L-peptide linking'          y ISOLEUCINE                               ? 'C6 H13 N O2'       131.173 
LEU 'L-peptide linking'          y LEUCINE                                  ? 'C6 H13 N O2'       131.173 
LYS 'L-peptide linking'          y LYSINE                                   ? 'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking'          y METHIONINE                               ? 'C5 H11 N O2 S'     149.211 
NAG 'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'       221.208 
PHE 'L-peptide linking'          y PHENYLALANINE                            ? 'C9 H11 N O2'       165.189 
PRO 'L-peptide linking'          y PROLINE                                  ? 'C5 H9 N O2'        115.130 
SER 'L-peptide linking'          y SERINE                                   ? 'C3 H7 N O3'        105.093 
THR 'L-peptide linking'          y THREONINE                                ? 'C4 H9 N O3'        119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                               ? 'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking'          y TYROSINE                                 ? 'C9 H11 N O3'       181.189 
VAL 'L-peptide linking'          y VALINE                                   ? 'C5 H11 N O2'       117.146 
VRW non-polymer                  . Nanvuranlat                              
'(2~{S})-2-azanyl-3-[4-[(5-azanyl-2-phenyl-1,3-benzoxazol-7-yl)methoxy]-3,5-bis(chloranyl)phenyl]propanoic acid' 
'C23 H19 Cl2 N3 O4' 472.321 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   0   ?   ?   ?   A . n 
A 1 2   SER 2   1   ?   ?   ?   A . n 
A 1 3   GLU 3   2   ?   ?   ?   A . n 
A 1 4   LEU 4   3   ?   ?   ?   A . n 
A 1 5   GLN 5   4   ?   ?   ?   A . n 
A 1 6   PRO 6   5   ?   ?   ?   A . n 
A 1 7   PRO 7   6   ?   ?   ?   A . n 
A 1 8   GLU 8   7   ?   ?   ?   A . n 
A 1 9   ALA 9   8   ?   ?   ?   A . n 
A 1 10  SER 10  9   ?   ?   ?   A . n 
A 1 11  ILE 11  10  ?   ?   ?   A . n 
A 1 12  ALA 12  11  ?   ?   ?   A . n 
A 1 13  VAL 13  12  ?   ?   ?   A . n 
A 1 14  VAL 14  13  ?   ?   ?   A . n 
A 1 15  SER 15  14  ?   ?   ?   A . n 
A 1 16  ILE 16  15  ?   ?   ?   A . n 
A 1 17  PRO 17  16  ?   ?   ?   A . n 
A 1 18  ARG 18  17  ?   ?   ?   A . n 
A 1 19  GLN 19  18  ?   ?   ?   A . n 
A 1 20  LEU 20  19  ?   ?   ?   A . n 
A 1 21  PRO 21  20  ?   ?   ?   A . n 
A 1 22  GLY 22  21  ?   ?   ?   A . n 
A 1 23  SER 23  22  ?   ?   ?   A . n 
A 1 24  HIS 24  23  ?   ?   ?   A . n 
A 1 25  SER 25  24  ?   ?   ?   A . n 
A 1 26  GLU 26  25  ?   ?   ?   A . n 
A 1 27  ALA 27  26  ?   ?   ?   A . n 
A 1 28  GLY 28  27  ?   ?   ?   A . n 
A 1 29  VAL 29  28  ?   ?   ?   A . n 
A 1 30  GLN 30  29  ?   ?   ?   A . n 
A 1 31  GLY 31  30  ?   ?   ?   A . n 
A 1 32  LEU 32  31  ?   ?   ?   A . n 
A 1 33  SER 33  32  ?   ?   ?   A . n 
A 1 34  ALA 34  33  ?   ?   ?   A . n 
A 1 35  GLY 35  34  ?   ?   ?   A . n 
A 1 36  ASP 36  35  ?   ?   ?   A . n 
A 1 37  ASP 37  36  ?   ?   ?   A . n 
A 1 38  SER 38  37  ?   ?   ?   A . n 
A 1 39  GLU 39  38  ?   ?   ?   A . n 
A 1 40  LEU 40  39  ?   ?   ?   A . n 
A 1 41  GLY 41  40  ?   ?   ?   A . n 
A 1 42  SER 42  41  ?   ?   ?   A . n 
A 1 43  HIS 43  42  ?   ?   ?   A . n 
A 1 44  CYS 44  43  ?   ?   ?   A . n 
A 1 45  VAL 45  44  ?   ?   ?   A . n 
A 1 46  ALA 46  45  ?   ?   ?   A . n 
A 1 47  GLN 47  46  ?   ?   ?   A . n 
A 1 48  THR 48  47  ?   ?   ?   A . n 
A 1 49  GLY 49  48  ?   ?   ?   A . n 
A 1 50  LEU 50  49  ?   ?   ?   A . n 
A 1 51  GLU 51  50  ?   ?   ?   A . n 
A 1 52  LEU 52  51  ?   ?   ?   A . n 
A 1 53  LEU 53  52  ?   ?   ?   A . n 
A 1 54  ALA 54  53  ?   ?   ?   A . n 
A 1 55  SER 55  54  ?   ?   ?   A . n 
A 1 56  GLY 56  55  ?   ?   ?   A . n 
A 1 57  ASP 57  56  ?   ?   ?   A . n 
A 1 58  PRO 58  57  ?   ?   ?   A . n 
A 1 59  LEU 59  58  ?   ?   ?   A . n 
A 1 60  PRO 60  59  ?   ?   ?   A . n 
A 1 61  SER 61  60  ?   ?   ?   A . n 
A 1 62  ALA 62  61  ?   ?   ?   A . n 
A 1 63  SER 63  62  ?   ?   ?   A . n 
A 1 64  GLN 64  63  ?   ?   ?   A . n 
A 1 65  ASN 65  64  ?   ?   ?   A . n 
A 1 66  ALA 66  65  ?   ?   ?   A . n 
A 1 67  GLU 67  66  ?   ?   ?   A . n 
A 1 68  MET 68  67  ?   ?   ?   A . n 
A 1 69  ILE 69  68  ?   ?   ?   A . n 
A 1 70  GLU 70  69  ?   ?   ?   A . n 
A 1 71  THR 71  70  ?   ?   ?   A . n 
A 1 72  GLY 72  71  ?   ?   ?   A . n 
A 1 73  SER 73  72  ?   ?   ?   A . n 
A 1 74  ASP 74  73  ?   ?   ?   A . n 
A 1 75  CYS 75  74  ?   ?   ?   A . n 
A 1 76  VAL 76  75  ?   ?   ?   A . n 
A 1 77  THR 77  76  ?   ?   ?   A . n 
A 1 78  GLN 78  77  ?   ?   ?   A . n 
A 1 79  ALA 79  78  ?   ?   ?   A . n 
A 1 80  GLY 80  79  ?   ?   ?   A . n 
A 1 81  LEU 81  80  ?   ?   ?   A . n 
A 1 82  GLN 82  81  ?   ?   ?   A . n 
A 1 83  LEU 83  82  ?   ?   ?   A . n 
A 1 84  LEU 84  83  ?   ?   ?   A . n 
A 1 85  ALA 85  84  ?   ?   ?   A . n 
A 1 86  SER 86  85  ?   ?   ?   A . n 
A 1 87  SER 87  86  ?   ?   ?   A . n 
A 1 88  ASP 88  87  ?   ?   ?   A . n 
A 1 89  PRO 89  88  ?   ?   ?   A . n 
A 1 90  PRO 90  89  ?   ?   ?   A . n 
A 1 91  ALA 91  90  ?   ?   ?   A . n 
A 1 92  LEU 92  91  ?   ?   ?   A . n 
A 1 93  ALA 93  92  ?   ?   ?   A . n 
A 1 94  SER 94  93  ?   ?   ?   A . n 
A 1 95  LYS 95  94  ?   ?   ?   A . n 
A 1 96  ASN 96  95  ?   ?   ?   A . n 
A 1 97  ALA 97  96  ?   ?   ?   A . n 
A 1 98  GLU 98  97  ?   ?   ?   A . n 
A 1 99  VAL 99  98  ?   ?   ?   A . n 
A 1 100 THR 100 99  ?   ?   ?   A . n 
A 1 101 GLY 101 100 ?   ?   ?   A . n 
A 1 102 THR 102 101 ?   ?   ?   A . n 
A 1 103 MET 103 102 ?   ?   ?   A . n 
A 1 104 SER 104 103 ?   ?   ?   A . n 
A 1 105 GLN 105 104 ?   ?   ?   A . n 
A 1 106 ASP 106 105 ?   ?   ?   A . n 
A 1 107 THR 107 106 ?   ?   ?   A . n 
A 1 108 GLU 108 107 ?   ?   ?   A . n 
A 1 109 VAL 109 108 ?   ?   ?   A . n 
A 1 110 ASP 110 109 ?   ?   ?   A . n 
A 1 111 MET 111 110 ?   ?   ?   A . n 
A 1 112 LYS 112 111 ?   ?   ?   A . n 
A 1 113 GLU 113 112 ?   ?   ?   A . n 
A 1 114 VAL 114 113 ?   ?   ?   A . n 
A 1 115 GLU 115 114 ?   ?   ?   A . n 
A 1 116 LEU 116 115 ?   ?   ?   A . n 
A 1 117 ASN 117 116 ?   ?   ?   A . n 
A 1 118 GLU 118 117 ?   ?   ?   A . n 
A 1 119 LEU 119 118 ?   ?   ?   A . n 
A 1 120 GLU 120 119 ?   ?   ?   A . n 
A 1 121 PRO 121 120 ?   ?   ?   A . n 
A 1 122 GLU 122 121 ?   ?   ?   A . n 
A 1 123 LYS 123 122 ?   ?   ?   A . n 
A 1 124 GLN 124 123 ?   ?   ?   A . n 
A 1 125 PRO 125 124 ?   ?   ?   A . n 
A 1 126 MET 126 125 ?   ?   ?   A . n 
A 1 127 ASN 127 126 ?   ?   ?   A . n 
A 1 128 ALA 128 127 ?   ?   ?   A . n 
A 1 129 ALA 129 128 ?   ?   ?   A . n 
A 1 130 SER 130 129 ?   ?   ?   A . n 
A 1 131 GLY 131 130 ?   ?   ?   A . n 
A 1 132 ALA 132 131 ?   ?   ?   A . n 
A 1 133 ALA 133 132 ?   ?   ?   A . n 
A 1 134 MET 134 133 ?   ?   ?   A . n 
A 1 135 SER 135 134 ?   ?   ?   A . n 
A 1 136 LEU 136 135 ?   ?   ?   A . n 
A 1 137 ALA 137 136 ?   ?   ?   A . n 
A 1 138 GLY 138 137 ?   ?   ?   A . n 
A 1 139 ALA 139 138 ?   ?   ?   A . n 
A 1 140 GLU 140 139 ?   ?   ?   A . n 
A 1 141 LYS 141 140 ?   ?   ?   A . n 
A 1 142 ASN 142 141 ?   ?   ?   A . n 
A 1 143 GLY 143 142 ?   ?   ?   A . n 
A 1 144 LEU 144 143 ?   ?   ?   A . n 
A 1 145 VAL 145 144 ?   ?   ?   A . n 
A 1 146 LYS 146 145 ?   ?   ?   A . n 
A 1 147 ILE 147 146 ?   ?   ?   A . n 
A 1 148 LYS 148 147 ?   ?   ?   A . n 
A 1 149 VAL 149 148 ?   ?   ?   A . n 
A 1 150 ALA 150 149 ?   ?   ?   A . n 
A 1 151 GLU 151 150 ?   ?   ?   A . n 
A 1 152 ASP 152 151 ?   ?   ?   A . n 
A 1 153 GLU 153 152 ?   ?   ?   A . n 
A 1 154 ALA 154 153 ?   ?   ?   A . n 
A 1 155 GLU 155 154 ?   ?   ?   A . n 
A 1 156 ALA 156 155 ?   ?   ?   A . n 
A 1 157 ALA 157 156 ?   ?   ?   A . n 
A 1 158 ALA 158 157 ?   ?   ?   A . n 
A 1 159 ALA 159 158 ?   ?   ?   A . n 
A 1 160 ALA 160 159 ?   ?   ?   A . n 
A 1 161 LYS 161 160 ?   ?   ?   A . n 
A 1 162 PHE 162 161 ?   ?   ?   A . n 
A 1 163 THR 163 162 162 THR THR A . n 
A 1 164 GLY 164 163 163 GLY GLY A . n 
A 1 165 LEU 165 164 164 LEU LEU A . n 
A 1 166 SER 166 165 165 SER SER A . n 
A 1 167 LYS 167 166 166 LYS LYS A . n 
A 1 168 GLU 168 167 167 GLU GLU A . n 
A 1 169 GLU 169 168 168 GLU GLU A . n 
A 1 170 LEU 170 169 169 LEU LEU A . n 
A 1 171 LEU 171 170 170 LEU LEU A . n 
A 1 172 LYS 172 171 171 LYS LYS A . n 
A 1 173 VAL 173 172 172 VAL VAL A . n 
A 1 174 ALA 174 173 173 ALA ALA A . n 
A 1 175 GLY 175 174 174 GLY GLY A . n 
A 1 176 SER 176 175 175 SER SER A . n 
A 1 177 PRO 177 176 176 PRO PRO A . n 
A 1 178 GLY 178 177 177 GLY GLY A . n 
A 1 179 TRP 179 178 178 TRP TRP A . n 
A 1 180 VAL 180 179 179 VAL VAL A . n 
A 1 181 ARG 181 180 180 ARG ARG A . n 
A 1 182 THR 182 181 181 THR THR A . n 
A 1 183 ARG 183 182 182 ARG ARG A . n 
A 1 184 TRP 184 183 183 TRP TRP A . n 
A 1 185 ALA 185 184 184 ALA ALA A . n 
A 1 186 LEU 186 185 185 LEU LEU A . n 
A 1 187 LEU 187 186 186 LEU LEU A . n 
A 1 188 LEU 188 187 187 LEU LEU A . n 
A 1 189 LEU 189 188 188 LEU LEU A . n 
A 1 190 PHE 190 189 189 PHE PHE A . n 
A 1 191 TRP 191 190 190 TRP TRP A . n 
A 1 192 LEU 192 191 191 LEU LEU A . n 
A 1 193 GLY 193 192 192 GLY GLY A . n 
A 1 194 TRP 194 193 193 TRP TRP A . n 
A 1 195 LEU 195 194 194 LEU LEU A . n 
A 1 196 GLY 196 195 195 GLY GLY A . n 
A 1 197 MET 197 196 196 MET MET A . n 
A 1 198 LEU 198 197 197 LEU LEU A . n 
A 1 199 ALA 199 198 198 ALA ALA A . n 
A 1 200 GLY 200 199 199 GLY GLY A . n 
A 1 201 ALA 201 200 200 ALA ALA A . n 
A 1 202 VAL 202 201 201 VAL VAL A . n 
A 1 203 VAL 203 202 202 VAL VAL A . n 
A 1 204 ILE 204 203 203 ILE ILE A . n 
A 1 205 ILE 205 204 204 ILE ILE A . n 
A 1 206 VAL 206 205 205 VAL VAL A . n 
A 1 207 ARG 207 206 206 ARG ARG A . n 
A 1 208 ALA 208 207 207 ALA ALA A . n 
A 1 209 PRO 209 208 208 PRO PRO A . n 
A 1 210 ARG 210 209 209 ARG ARG A . n 
A 1 211 CYS 211 210 210 CYS CYS A . n 
A 1 212 ARG 212 211 211 ARG ARG A . n 
A 1 213 GLU 213 212 212 GLU GLU A . n 
A 1 214 LEU 214 213 213 LEU LEU A . n 
A 1 215 PRO 215 214 214 PRO PRO A . n 
A 1 216 ALA 216 215 215 ALA ALA A . n 
A 1 217 GLN 217 216 216 GLN GLN A . n 
A 1 218 LYS 218 217 217 LYS LYS A . n 
A 1 219 TRP 219 218 218 TRP TRP A . n 
A 1 220 TRP 220 219 219 TRP TRP A . n 
A 1 221 HIS 221 220 220 HIS HIS A . n 
A 1 222 THR 222 221 221 THR THR A . n 
A 1 223 GLY 223 222 222 GLY GLY A . n 
A 1 224 ALA 224 223 223 ALA ALA A . n 
A 1 225 LEU 225 224 224 LEU LEU A . n 
A 1 226 TYR 226 225 225 TYR TYR A . n 
A 1 227 ARG 227 226 226 ARG ARG A . n 
A 1 228 ILE 228 227 227 ILE ILE A . n 
A 1 229 GLY 229 228 228 GLY GLY A . n 
A 1 230 ASP 230 229 229 ASP ASP A . n 
A 1 231 LEU 231 230 230 LEU LEU A . n 
A 1 232 GLN 232 231 231 GLN GLN A . n 
A 1 233 ALA 233 232 232 ALA ALA A . n 
A 1 234 PHE 234 233 233 PHE PHE A . n 
A 1 235 GLN 235 234 234 GLN GLN A . n 
A 1 236 GLY 236 235 235 GLY GLY A . n 
A 1 237 HIS 237 236 236 HIS HIS A . n 
A 1 238 GLY 238 237 237 GLY GLY A . n 
A 1 239 ALA 239 238 238 ALA ALA A . n 
A 1 240 GLY 240 239 239 GLY GLY A . n 
A 1 241 ASN 241 240 240 ASN ASN A . n 
A 1 242 LEU 242 241 241 LEU LEU A . n 
A 1 243 ALA 243 242 242 ALA ALA A . n 
A 1 244 GLY 244 243 243 GLY GLY A . n 
A 1 245 LEU 245 244 244 LEU LEU A . n 
A 1 246 LYS 246 245 245 LYS LYS A . n 
A 1 247 GLY 247 246 246 GLY GLY A . n 
A 1 248 ARG 248 247 247 ARG ARG A . n 
A 1 249 LEU 249 248 248 LEU LEU A . n 
A 1 250 ASP 250 249 249 ASP ASP A . n 
A 1 251 TYR 251 250 250 TYR TYR A . n 
A 1 252 LEU 252 251 251 LEU LEU A . n 
A 1 253 SER 253 252 252 SER SER A . n 
A 1 254 SER 254 253 253 SER SER A . n 
A 1 255 LEU 255 254 254 LEU LEU A . n 
A 1 256 LYS 256 255 255 LYS LYS A . n 
A 1 257 VAL 257 256 256 VAL VAL A . n 
A 1 258 LYS 258 257 257 LYS LYS A . n 
A 1 259 GLY 259 258 258 GLY GLY A . n 
A 1 260 LEU 260 259 259 LEU LEU A . n 
A 1 261 VAL 261 260 260 VAL VAL A . n 
A 1 262 LEU 262 261 261 LEU LEU A . n 
A 1 263 GLY 263 262 262 GLY GLY A . n 
A 1 264 PRO 264 263 263 PRO PRO A . n 
A 1 265 ILE 265 264 264 ILE ILE A . n 
A 1 266 HIS 266 265 265 HIS HIS A . n 
A 1 267 LYS 267 266 266 LYS LYS A . n 
A 1 268 ASN 268 267 267 ASN ASN A . n 
A 1 269 GLN 269 268 268 GLN GLN A . n 
A 1 270 LYS 270 269 269 LYS LYS A . n 
A 1 271 ASP 271 270 270 ASP ASP A . n 
A 1 272 ASP 272 271 271 ASP ASP A . n 
A 1 273 VAL 273 272 272 VAL VAL A . n 
A 1 274 ALA 274 273 273 ALA ALA A . n 
A 1 275 GLN 275 274 274 GLN GLN A . n 
A 1 276 THR 276 275 275 THR THR A . n 
A 1 277 ASP 277 276 276 ASP ASP A . n 
A 1 278 LEU 278 277 277 LEU LEU A . n 
A 1 279 LEU 279 278 278 LEU LEU A . n 
A 1 280 GLN 280 279 279 GLN GLN A . n 
A 1 281 ILE 281 280 280 ILE ILE A . n 
A 1 282 ASP 282 281 281 ASP ASP A . n 
A 1 283 PRO 283 282 282 PRO PRO A . n 
A 1 284 ASN 284 283 283 ASN ASN A . n 
A 1 285 PHE 285 284 284 PHE PHE A . n 
A 1 286 GLY 286 285 285 GLY GLY A . n 
A 1 287 SER 287 286 286 SER SER A . n 
A 1 288 LYS 288 287 287 LYS LYS A . n 
A 1 289 GLU 289 288 288 GLU GLU A . n 
A 1 290 ASP 290 289 289 ASP ASP A . n 
A 1 291 PHE 291 290 290 PHE PHE A . n 
A 1 292 ASP 292 291 291 ASP ASP A . n 
A 1 293 SER 293 292 292 SER SER A . n 
A 1 294 LEU 294 293 293 LEU LEU A . n 
A 1 295 LEU 295 294 294 LEU LEU A . n 
A 1 296 GLN 296 295 295 GLN GLN A . n 
A 1 297 SER 297 296 296 SER SER A . n 
A 1 298 ALA 298 297 297 ALA ALA A . n 
A 1 299 LYS 299 298 298 LYS LYS A . n 
A 1 300 LYS 300 299 299 LYS LYS A . n 
A 1 301 LYS 301 300 300 LYS LYS A . n 
A 1 302 SER 302 301 301 SER SER A . n 
A 1 303 ILE 303 302 302 ILE ILE A . n 
A 1 304 ARG 304 303 303 ARG ARG A . n 
A 1 305 VAL 305 304 304 VAL VAL A . n 
A 1 306 ILE 306 305 305 ILE ILE A . n 
A 1 307 LEU 307 306 306 LEU LEU A . n 
A 1 308 ASP 308 307 307 ASP ASP A . n 
A 1 309 LEU 309 308 308 LEU LEU A . n 
A 1 310 THR 310 309 309 THR THR A . n 
A 1 311 PRO 311 310 310 PRO PRO A . n 
A 1 312 ASN 312 311 311 ASN ASN A . n 
A 1 313 TYR 313 312 312 TYR TYR A . n 
A 1 314 ARG 314 313 313 ARG ARG A . n 
A 1 315 GLY 315 314 314 GLY GLY A . n 
A 1 316 GLU 316 315 315 GLU GLU A . n 
A 1 317 ASN 317 316 316 ASN ASN A . n 
A 1 318 SER 318 317 317 SER SER A . n 
A 1 319 TRP 319 318 318 TRP TRP A . n 
A 1 320 PHE 320 319 319 PHE PHE A . n 
A 1 321 SER 321 320 320 SER SER A . n 
A 1 322 THR 322 321 321 THR THR A . n 
A 1 323 GLN 323 322 322 GLN GLN A . n 
A 1 324 VAL 324 323 323 VAL VAL A . n 
A 1 325 ASP 325 324 324 ASP ASP A . n 
A 1 326 THR 326 325 325 THR THR A . n 
A 1 327 VAL 327 326 326 VAL VAL A . n 
A 1 328 ALA 328 327 327 ALA ALA A . n 
A 1 329 THR 329 328 328 THR THR A . n 
A 1 330 LYS 330 329 329 LYS LYS A . n 
A 1 331 VAL 331 330 330 VAL VAL A . n 
A 1 332 LYS 332 331 331 LYS LYS A . n 
A 1 333 ASP 333 332 332 ASP ASP A . n 
A 1 334 ALA 334 333 333 ALA ALA A . n 
A 1 335 LEU 335 334 334 LEU LEU A . n 
A 1 336 GLU 336 335 335 GLU GLU A . n 
A 1 337 PHE 337 336 336 PHE PHE A . n 
A 1 338 TRP 338 337 337 TRP TRP A . n 
A 1 339 LEU 339 338 338 LEU LEU A . n 
A 1 340 GLN 340 339 339 GLN GLN A . n 
A 1 341 ALA 341 340 340 ALA ALA A . n 
A 1 342 GLY 342 341 341 GLY GLY A . n 
A 1 343 VAL 343 342 342 VAL VAL A . n 
A 1 344 ASP 344 343 343 ASP ASP A . n 
A 1 345 GLY 345 344 344 GLY GLY A . n 
A 1 346 PHE 346 345 345 PHE PHE A . n 
A 1 347 GLN 347 346 346 GLN GLN A . n 
A 1 348 VAL 348 347 347 VAL VAL A . n 
A 1 349 ARG 349 348 348 ARG ARG A . n 
A 1 350 ASP 350 349 349 ASP ASP A . n 
A 1 351 ILE 351 350 350 ILE ILE A . n 
A 1 352 GLU 352 351 351 GLU GLU A . n 
A 1 353 ASN 353 352 352 ASN ASN A . n 
A 1 354 LEU 354 353 353 LEU LEU A . n 
A 1 355 LYS 355 354 354 LYS LYS A . n 
A 1 356 ASP 356 355 355 ASP ASP A . n 
A 1 357 ALA 357 356 356 ALA ALA A . n 
A 1 358 SER 358 357 357 SER SER A . n 
A 1 359 SER 359 358 358 SER SER A . n 
A 1 360 PHE 360 359 359 PHE PHE A . n 
A 1 361 LEU 361 360 360 LEU LEU A . n 
A 1 362 ALA 362 361 361 ALA ALA A . n 
A 1 363 GLU 363 362 362 GLU GLU A . n 
A 1 364 TRP 364 363 363 TRP TRP A . n 
A 1 365 GLN 365 364 364 GLN GLN A . n 
A 1 366 ASN 366 365 365 ASN ASN A . n 
A 1 367 ILE 367 366 366 ILE ILE A . n 
A 1 368 THR 368 367 367 THR THR A . n 
A 1 369 LYS 369 368 368 LYS LYS A . n 
A 1 370 GLY 370 369 369 GLY GLY A . n 
A 1 371 PHE 371 370 370 PHE PHE A . n 
A 1 372 SER 372 371 371 SER SER A . n 
A 1 373 GLU 373 372 372 GLU GLU A . n 
A 1 374 ASP 374 373 373 ASP ASP A . n 
A 1 375 ARG 375 374 374 ARG ARG A . n 
A 1 376 LEU 376 375 375 LEU LEU A . n 
A 1 377 LEU 377 376 376 LEU LEU A . n 
A 1 378 ILE 378 377 377 ILE ILE A . n 
A 1 379 ALA 379 378 378 ALA ALA A . n 
A 1 380 GLY 380 379 379 GLY GLY A . n 
A 1 381 THR 381 380 380 THR THR A . n 
A 1 382 ASN 382 381 381 ASN ASN A . n 
A 1 383 SER 383 382 382 SER SER A . n 
A 1 384 SER 384 383 383 SER SER A . n 
A 1 385 ASP 385 384 384 ASP ASP A . n 
A 1 386 LEU 386 385 385 LEU LEU A . n 
A 1 387 GLN 387 386 386 GLN GLN A . n 
A 1 388 GLN 388 387 387 GLN GLN A . n 
A 1 389 ILE 389 388 388 ILE ILE A . n 
A 1 390 LEU 390 389 389 LEU LEU A . n 
A 1 391 SER 391 390 390 SER SER A . n 
A 1 392 LEU 392 391 391 LEU LEU A . n 
A 1 393 LEU 393 392 392 LEU LEU A . n 
A 1 394 GLU 394 393 393 GLU GLU A . n 
A 1 395 SER 395 394 394 SER SER A . n 
A 1 396 ASN 396 395 395 ASN ASN A . n 
A 1 397 LYS 397 396 396 LYS LYS A . n 
A 1 398 ASP 398 397 397 ASP ASP A . n 
A 1 399 LEU 399 398 398 LEU LEU A . n 
A 1 400 LEU 400 399 399 LEU LEU A . n 
A 1 401 LEU 401 400 400 LEU LEU A . n 
A 1 402 THR 402 401 401 THR THR A . n 
A 1 403 SER 403 402 402 SER SER A . n 
A 1 404 SER 404 403 403 SER SER A . n 
A 1 405 TYR 405 404 404 TYR TYR A . n 
A 1 406 LEU 406 405 405 LEU LEU A . n 
A 1 407 SER 407 406 406 SER SER A . n 
A 1 408 ASP 408 407 407 ASP ASP A . n 
A 1 409 SER 409 408 408 SER SER A . n 
A 1 410 GLY 410 409 409 GLY GLY A . n 
A 1 411 SER 411 410 410 SER SER A . n 
A 1 412 THR 412 411 411 THR THR A . n 
A 1 413 GLY 413 412 412 GLY GLY A . n 
A 1 414 GLU 414 413 413 GLU GLU A . n 
A 1 415 HIS 415 414 414 HIS HIS A . n 
A 1 416 THR 416 415 415 THR THR A . n 
A 1 417 LYS 417 416 416 LYS LYS A . n 
A 1 418 SER 418 417 417 SER SER A . n 
A 1 419 LEU 419 418 418 LEU LEU A . n 
A 1 420 VAL 420 419 419 VAL VAL A . n 
A 1 421 THR 421 420 420 THR THR A . n 
A 1 422 GLN 422 421 421 GLN GLN A . n 
A 1 423 TYR 423 422 422 TYR TYR A . n 
A 1 424 LEU 424 423 423 LEU LEU A . n 
A 1 425 ASN 425 424 424 ASN ASN A . n 
A 1 426 ALA 426 425 425 ALA ALA A . n 
A 1 427 THR 427 426 426 THR THR A . n 
A 1 428 GLY 428 427 427 GLY GLY A . n 
A 1 429 ASN 429 428 428 ASN ASN A . n 
A 1 430 ARG 430 429 429 ARG ARG A . n 
A 1 431 TRP 431 430 430 TRP TRP A . n 
A 1 432 CYS 432 431 431 CYS CYS A . n 
A 1 433 SER 433 432 432 SER SER A . n 
A 1 434 TRP 434 433 433 TRP TRP A . n 
A 1 435 SER 435 434 434 SER SER A . n 
A 1 436 LEU 436 435 435 LEU LEU A . n 
A 1 437 SER 437 436 436 SER SER A . n 
A 1 438 GLN 438 437 437 GLN GLN A . n 
A 1 439 ALA 439 438 438 ALA ALA A . n 
A 1 440 ARG 440 439 439 ARG ARG A . n 
A 1 441 LEU 441 440 440 LEU LEU A . n 
A 1 442 LEU 442 441 441 LEU LEU A . n 
A 1 443 THR 443 442 442 THR THR A . n 
A 1 444 SER 444 443 443 SER SER A . n 
A 1 445 PHE 445 444 444 PHE PHE A . n 
A 1 446 LEU 446 445 445 LEU LEU A . n 
A 1 447 PRO 447 446 446 PRO PRO A . n 
A 1 448 ALA 448 447 447 ALA ALA A . n 
A 1 449 GLN 449 448 448 GLN GLN A . n 
A 1 450 LEU 450 449 449 LEU LEU A . n 
A 1 451 LEU 451 450 450 LEU LEU A . n 
A 1 452 ARG 452 451 451 ARG ARG A . n 
A 1 453 LEU 453 452 452 LEU LEU A . n 
A 1 454 TYR 454 453 453 TYR TYR A . n 
A 1 455 GLN 455 454 454 GLN GLN A . n 
A 1 456 LEU 456 455 455 LEU LEU A . n 
A 1 457 MET 457 456 456 MET MET A . n 
A 1 458 LEU 458 457 457 LEU LEU A . n 
A 1 459 PHE 459 458 458 PHE PHE A . n 
A 1 460 THR 460 459 459 THR THR A . n 
A 1 461 LEU 461 460 460 LEU LEU A . n 
A 1 462 PRO 462 461 461 PRO PRO A . n 
A 1 463 GLY 463 462 462 GLY GLY A . n 
A 1 464 THR 464 463 463 THR THR A . n 
A 1 465 PRO 465 464 464 PRO PRO A . n 
A 1 466 VAL 466 465 465 VAL VAL A . n 
A 1 467 PHE 467 466 466 PHE PHE A . n 
A 1 468 SER 468 467 467 SER SER A . n 
A 1 469 TYR 469 468 468 TYR TYR A . n 
A 1 470 GLY 470 469 469 GLY GLY A . n 
A 1 471 ASP 471 470 470 ASP ASP A . n 
A 1 472 GLU 472 471 471 GLU GLU A . n 
A 1 473 ILE 473 472 472 ILE ILE A . n 
A 1 474 GLY 474 473 473 GLY GLY A . n 
A 1 475 LEU 475 474 474 LEU LEU A . n 
A 1 476 ASP 476 475 475 ASP ASP A . n 
A 1 477 ALA 477 476 476 ALA ALA A . n 
A 1 478 ALA 478 477 477 ALA ALA A . n 
A 1 479 ALA 479 478 478 ALA ALA A . n 
A 1 480 LEU 480 479 479 LEU LEU A . n 
A 1 481 PRO 481 480 480 PRO PRO A . n 
A 1 482 GLY 482 481 481 GLY GLY A . n 
A 1 483 GLN 483 482 482 GLN GLN A . n 
A 1 484 PRO 484 483 483 PRO PRO A . n 
A 1 485 MET 485 484 484 MET MET A . n 
A 1 486 GLU 486 485 485 GLU GLU A . n 
A 1 487 ALA 487 486 486 ALA ALA A . n 
A 1 488 PRO 488 487 487 PRO PRO A . n 
A 1 489 VAL 489 488 488 VAL VAL A . n 
A 1 490 MET 490 489 489 MET MET A . n 
A 1 491 LEU 491 490 490 LEU LEU A . n 
A 1 492 TRP 492 491 491 TRP TRP A . n 
A 1 493 ASP 493 492 492 ASP ASP A . n 
A 1 494 GLU 494 493 493 GLU GLU A . n 
A 1 495 SER 495 494 494 SER SER A . n 
A 1 496 SER 496 495 495 SER SER A . n 
A 1 497 PHE 497 496 496 PHE PHE A . n 
A 1 498 PRO 498 497 497 PRO PRO A . n 
A 1 499 ASP 499 498 498 ASP ASP A . n 
A 1 500 ILE 500 499 499 ILE ILE A . n 
A 1 501 PRO 501 500 500 PRO PRO A . n 
A 1 502 GLY 502 501 501 GLY GLY A . n 
A 1 503 ALA 503 502 502 ALA ALA A . n 
A 1 504 VAL 504 503 503 VAL VAL A . n 
A 1 505 SER 505 504 504 SER SER A . n 
A 1 506 ALA 506 505 505 ALA ALA A . n 
A 1 507 ASN 507 506 506 ASN ASN A . n 
A 1 508 MET 508 507 507 MET MET A . n 
A 1 509 THR 509 508 508 THR THR A . n 
A 1 510 VAL 510 509 509 VAL VAL A . n 
A 1 511 LYS 511 510 510 LYS LYS A . n 
A 1 512 GLY 512 511 511 GLY GLY A . n 
A 1 513 GLN 513 512 512 GLN GLN A . n 
A 1 514 SER 514 513 513 SER SER A . n 
A 1 515 GLU 515 514 514 GLU GLU A . n 
A 1 516 ASP 516 515 515 ASP ASP A . n 
A 1 517 PRO 517 516 516 PRO PRO A . n 
A 1 518 GLY 518 517 517 GLY GLY A . n 
A 1 519 SER 519 518 518 SER SER A . n 
A 1 520 LEU 520 519 519 LEU LEU A . n 
A 1 521 LEU 521 520 520 LEU LEU A . n 
A 1 522 SER 522 521 521 SER SER A . n 
A 1 523 LEU 523 522 522 LEU LEU A . n 
A 1 524 PHE 524 523 523 PHE PHE A . n 
A 1 525 ARG 525 524 524 ARG ARG A . n 
A 1 526 ARG 526 525 525 ARG ARG A . n 
A 1 527 LEU 527 526 526 LEU LEU A . n 
A 1 528 SER 528 527 527 SER SER A . n 
A 1 529 ASP 529 528 528 ASP ASP A . n 
A 1 530 GLN 530 529 529 GLN GLN A . n 
A 1 531 ARG 531 530 530 ARG ARG A . n 
A 1 532 SER 532 531 531 SER SER A . n 
A 1 533 LYS 533 532 532 LYS LYS A . n 
A 1 534 GLU 534 533 533 GLU GLU A . n 
A 1 535 ARG 535 534 534 ARG ARG A . n 
A 1 536 SER 536 535 535 SER SER A . n 
A 1 537 LEU 537 536 536 LEU LEU A . n 
A 1 538 LEU 538 537 537 LEU LEU A . n 
A 1 539 HIS 539 538 538 HIS HIS A . n 
A 1 540 GLY 540 539 539 GLY GLY A . n 
A 1 541 ASP 541 540 540 ASP ASP A . n 
A 1 542 PHE 542 541 541 PHE PHE A . n 
A 1 543 HIS 543 542 542 HIS HIS A . n 
A 1 544 ALA 544 543 543 ALA ALA A . n 
A 1 545 PHE 545 544 544 PHE PHE A . n 
A 1 546 SER 546 545 545 SER SER A . n 
A 1 547 ALA 547 546 546 ALA ALA A . n 
A 1 548 GLY 548 547 547 GLY GLY A . n 
A 1 549 PRO 549 548 548 PRO PRO A . n 
A 1 550 GLY 550 549 549 GLY GLY A . n 
A 1 551 LEU 551 550 550 LEU LEU A . n 
A 1 552 PHE 552 551 551 PHE PHE A . n 
A 1 553 SER 553 552 552 SER SER A . n 
A 1 554 TYR 554 553 553 TYR TYR A . n 
A 1 555 ILE 555 554 554 ILE ILE A . n 
A 1 556 ARG 556 555 555 ARG ARG A . n 
A 1 557 HIS 557 556 556 HIS HIS A . n 
A 1 558 TRP 558 557 557 TRP TRP A . n 
A 1 559 ASP 559 558 558 ASP ASP A . n 
A 1 560 GLN 560 559 559 GLN GLN A . n 
A 1 561 ASN 561 560 560 ASN ASN A . n 
A 1 562 GLU 562 561 561 GLU GLU A . n 
A 1 563 ARG 563 562 562 ARG ARG A . n 
A 1 564 PHE 564 563 563 PHE PHE A . n 
A 1 565 LEU 565 564 564 LEU LEU A . n 
A 1 566 VAL 566 565 565 VAL VAL A . n 
A 1 567 VAL 567 566 566 VAL VAL A . n 
A 1 568 LEU 568 567 567 LEU LEU A . n 
A 1 569 ASN 569 568 568 ASN ASN A . n 
A 1 570 PHE 570 569 569 PHE PHE A . n 
A 1 571 GLY 571 570 570 GLY GLY A . n 
A 1 572 ASP 572 571 571 ASP ASP A . n 
A 1 573 VAL 573 572 572 VAL VAL A . n 
A 1 574 GLY 574 573 573 GLY GLY A . n 
A 1 575 LEU 575 574 574 LEU LEU A . n 
A 1 576 SER 576 575 575 SER SER A . n 
A 1 577 ALA 577 576 576 ALA ALA A . n 
A 1 578 GLY 578 577 577 GLY GLY A . n 
A 1 579 LEU 579 578 578 LEU LEU A . n 
A 1 580 GLN 580 579 579 GLN GLN A . n 
A 1 581 ALA 581 580 580 ALA ALA A . n 
A 1 582 SER 582 581 581 SER SER A . n 
A 1 583 ASP 583 582 582 ASP ASP A . n 
A 1 584 LEU 584 583 583 LEU LEU A . n 
A 1 585 PRO 585 584 584 PRO PRO A . n 
A 1 586 ALA 586 585 585 ALA ALA A . n 
A 1 587 SER 587 586 586 SER SER A . n 
A 1 588 ALA 588 587 587 ALA ALA A . n 
A 1 589 SER 589 588 588 SER SER A . n 
A 1 590 LEU 590 589 589 LEU LEU A . n 
A 1 591 PRO 591 590 590 PRO PRO A . n 
A 1 592 ALA 592 591 591 ALA ALA A . n 
A 1 593 LYS 593 592 592 LYS LYS A . n 
A 1 594 ALA 594 593 593 ALA ALA A . n 
A 1 595 ASP 595 594 594 ASP ASP A . n 
A 1 596 LEU 596 595 595 LEU LEU A . n 
A 1 597 LEU 597 596 596 LEU LEU A . n 
A 1 598 LEU 598 597 597 LEU LEU A . n 
A 1 599 SER 599 598 598 SER SER A . n 
A 1 600 THR 600 599 599 THR THR A . n 
A 1 601 GLN 601 600 600 GLN GLN A . n 
A 1 602 PRO 602 601 601 PRO PRO A . n 
A 1 603 GLY 603 602 602 GLY GLY A . n 
A 1 604 ARG 604 603 603 ARG ARG A . n 
A 1 605 GLU 605 604 604 GLU GLU A . n 
A 1 606 GLU 606 605 605 GLU GLU A . n 
A 1 607 GLY 607 606 606 GLY GLY A . n 
A 1 608 SER 608 607 607 SER SER A . n 
A 1 609 PRO 609 608 608 PRO PRO A . n 
A 1 610 LEU 610 609 609 LEU LEU A . n 
A 1 611 GLU 611 610 610 GLU GLU A . n 
A 1 612 LEU 612 611 611 LEU LEU A . n 
A 1 613 GLU 613 612 612 GLU GLU A . n 
A 1 614 ARG 614 613 613 ARG ARG A . n 
A 1 615 LEU 615 614 614 LEU LEU A . n 
A 1 616 LYS 616 615 615 LYS LYS A . n 
A 1 617 LEU 617 616 616 LEU LEU A . n 
A 1 618 GLU 618 617 617 GLU GLU A . n 
A 1 619 PRO 619 618 618 PRO PRO A . n 
A 1 620 HIS 620 619 619 HIS HIS A . n 
A 1 621 GLU 621 620 620 GLU GLU A . n 
A 1 622 GLY 622 621 621 GLY GLY A . n 
A 1 623 LEU 623 622 622 LEU LEU A . n 
A 1 624 LEU 624 623 623 LEU LEU A . n 
A 1 625 LEU 625 624 624 LEU LEU A . n 
A 1 626 ARG 626 625 625 ARG ARG A . n 
A 1 627 PHE 627 626 626 PHE PHE A . n 
A 1 628 PRO 628 627 627 PRO PRO A . n 
A 1 629 TYR 629 628 628 TYR TYR A . n 
A 1 630 ALA 630 629 629 ALA ALA A . n 
A 1 631 ALA 631 630 630 ALA ALA A . n 
B 2 1   MET 1   1   ?   ?   ?   B . n 
B 2 2   ALA 2   2   ?   ?   ?   B . n 
B 2 3   GLY 3   3   ?   ?   ?   B . n 
B 2 4   ALA 4   4   ?   ?   ?   B . n 
B 2 5   GLY 5   5   ?   ?   ?   B . n 
B 2 6   PRO 6   6   ?   ?   ?   B . n 
B 2 7   LYS 7   7   ?   ?   ?   B . n 
B 2 8   ARG 8   8   ?   ?   ?   B . n 
B 2 9   ARG 9   9   ?   ?   ?   B . n 
B 2 10  ALA 10  10  ?   ?   ?   B . n 
B 2 11  LEU 11  11  ?   ?   ?   B . n 
B 2 12  ALA 12  12  ?   ?   ?   B . n 
B 2 13  ALA 13  13  ?   ?   ?   B . n 
B 2 14  PRO 14  14  ?   ?   ?   B . n 
B 2 15  ALA 15  15  ?   ?   ?   B . n 
B 2 16  ALA 16  16  ?   ?   ?   B . n 
B 2 17  GLU 17  17  ?   ?   ?   B . n 
B 2 18  GLU 18  18  ?   ?   ?   B . n 
B 2 19  LYS 19  19  ?   ?   ?   B . n 
B 2 20  GLU 20  20  ?   ?   ?   B . n 
B 2 21  GLU 21  21  ?   ?   ?   B . n 
B 2 22  ALA 22  22  ?   ?   ?   B . n 
B 2 23  ARG 23  23  ?   ?   ?   B . n 
B 2 24  GLU 24  24  ?   ?   ?   B . n 
B 2 25  LYS 25  25  ?   ?   ?   B . n 
B 2 26  MET 26  26  ?   ?   ?   B . n 
B 2 27  LEU 27  27  ?   ?   ?   B . n 
B 2 28  ALA 28  28  ?   ?   ?   B . n 
B 2 29  ALA 29  29  ?   ?   ?   B . n 
B 2 30  LYS 30  30  ?   ?   ?   B . n 
B 2 31  SER 31  31  ?   ?   ?   B . n 
B 2 32  ALA 32  32  ?   ?   ?   B . n 
B 2 33  ASP 33  33  ?   ?   ?   B . n 
B 2 34  GLY 34  34  ?   ?   ?   B . n 
B 2 35  SER 35  35  ?   ?   ?   B . n 
B 2 36  ALA 36  36  ?   ?   ?   B . n 
B 2 37  PRO 37  37  ?   ?   ?   B . n 
B 2 38  ALA 38  38  ?   ?   ?   B . n 
B 2 39  GLY 39  39  ?   ?   ?   B . n 
B 2 40  GLU 40  40  ?   ?   ?   B . n 
B 2 41  GLY 41  41  ?   ?   ?   B . n 
B 2 42  GLU 42  42  ?   ?   ?   B . n 
B 2 43  GLY 43  43  43  GLY GLY B . n 
B 2 44  VAL 44  44  44  VAL VAL B . n 
B 2 45  THR 45  45  45  THR THR B . n 
B 2 46  LEU 46  46  46  LEU LEU B . n 
B 2 47  GLN 47  47  47  GLN GLN B . n 
B 2 48  ARG 48  48  48  ARG ARG B . n 
B 2 49  ASN 49  49  49  ASN ASN B . n 
B 2 50  ILE 50  50  50  ILE ILE B . n 
B 2 51  THR 51  51  51  THR THR B . n 
B 2 52  LEU 52  52  52  LEU LEU B . n 
B 2 53  LEU 53  53  53  LEU LEU B . n 
B 2 54  ASN 54  54  54  ASN ASN B . n 
B 2 55  GLY 55  55  55  GLY GLY B . n 
B 2 56  VAL 56  56  56  VAL VAL B . n 
B 2 57  ALA 57  57  57  ALA ALA B . n 
B 2 58  ILE 58  58  58  ILE ILE B . n 
B 2 59  ILE 59  59  59  ILE ILE B . n 
B 2 60  VAL 60  60  60  VAL VAL B . n 
B 2 61  GLY 61  61  61  GLY GLY B . n 
B 2 62  THR 62  62  62  THR THR B . n 
B 2 63  ILE 63  63  63  ILE ILE B . n 
B 2 64  ILE 64  64  64  ILE ILE B . n 
B 2 65  GLY 65  65  65  GLY GLY B . n 
B 2 66  SER 66  66  66  SER SER B . n 
B 2 67  GLY 67  67  67  GLY GLY B . n 
B 2 68  ILE 68  68  68  ILE ILE B . n 
B 2 69  PHE 69  69  69  PHE PHE B . n 
B 2 70  VAL 70  70  70  VAL VAL B . n 
B 2 71  THR 71  71  71  THR THR B . n 
B 2 72  PRO 72  72  72  PRO PRO B . n 
B 2 73  THR 73  73  73  THR THR B . n 
B 2 74  GLY 74  74  74  GLY GLY B . n 
B 2 75  VAL 75  75  75  VAL VAL B . n 
B 2 76  LEU 76  76  76  LEU LEU B . n 
B 2 77  LYS 77  77  77  LYS LYS B . n 
B 2 78  GLU 78  78  78  GLU GLU B . n 
B 2 79  ALA 79  79  79  ALA ALA B . n 
B 2 80  GLY 80  80  80  GLY GLY B . n 
B 2 81  SER 81  81  81  SER SER B . n 
B 2 82  PRO 82  82  82  PRO PRO B . n 
B 2 83  GLY 83  83  83  GLY GLY B . n 
B 2 84  LEU 84  84  84  LEU LEU B . n 
B 2 85  ALA 85  85  85  ALA ALA B . n 
B 2 86  LEU 86  86  86  LEU LEU B . n 
B 2 87  VAL 87  87  87  VAL VAL B . n 
B 2 88  VAL 88  88  88  VAL VAL B . n 
B 2 89  TRP 89  89  89  TRP TRP B . n 
B 2 90  ALA 90  90  90  ALA ALA B . n 
B 2 91  ALA 91  91  91  ALA ALA B . n 
B 2 92  CYS 92  92  92  CYS CYS B . n 
B 2 93  GLY 93  93  93  GLY GLY B . n 
B 2 94  VAL 94  94  94  VAL VAL B . n 
B 2 95  PHE 95  95  95  PHE PHE B . n 
B 2 96  SER 96  96  96  SER SER B . n 
B 2 97  ILE 97  97  97  ILE ILE B . n 
B 2 98  VAL 98  98  98  VAL VAL B . n 
B 2 99  GLY 99  99  99  GLY GLY B . n 
B 2 100 ALA 100 100 100 ALA ALA B . n 
B 2 101 LEU 101 101 101 LEU LEU B . n 
B 2 102 CYS 102 102 102 CYS CYS B . n 
B 2 103 TYR 103 103 103 TYR TYR B . n 
B 2 104 ALA 104 104 104 ALA ALA B . n 
B 2 105 GLU 105 105 105 GLU GLU B . n 
B 2 106 LEU 106 106 106 LEU LEU B . n 
B 2 107 GLY 107 107 107 GLY GLY B . n 
B 2 108 THR 108 108 108 THR THR B . n 
B 2 109 THR 109 109 109 THR THR B . n 
B 2 110 ILE 110 110 110 ILE ILE B . n 
B 2 111 SER 111 111 111 SER SER B . n 
B 2 112 LYS 112 112 112 LYS LYS B . n 
B 2 113 SER 113 113 113 SER SER B . n 
B 2 114 GLY 114 114 114 GLY GLY B . n 
B 2 115 GLY 115 115 115 GLY GLY B . n 
B 2 116 ASP 116 116 116 ASP ASP B . n 
B 2 117 TYR 117 117 117 TYR TYR B . n 
B 2 118 ALA 118 118 118 ALA ALA B . n 
B 2 119 TYR 119 119 119 TYR TYR B . n 
B 2 120 MET 120 120 120 MET MET B . n 
B 2 121 LEU 121 121 121 LEU LEU B . n 
B 2 122 GLU 122 122 122 GLU GLU B . n 
B 2 123 VAL 123 123 123 VAL VAL B . n 
B 2 124 TYR 124 124 124 TYR TYR B . n 
B 2 125 GLY 125 125 125 GLY GLY B . n 
B 2 126 SER 126 126 126 SER SER B . n 
B 2 127 LEU 127 127 127 LEU LEU B . n 
B 2 128 PRO 128 128 128 PRO PRO B . n 
B 2 129 ALA 129 129 129 ALA ALA B . n 
B 2 130 PHE 130 130 130 PHE PHE B . n 
B 2 131 LEU 131 131 131 LEU LEU B . n 
B 2 132 LYS 132 132 132 LYS LYS B . n 
B 2 133 LEU 133 133 133 LEU LEU B . n 
B 2 134 TRP 134 134 134 TRP TRP B . n 
B 2 135 ILE 135 135 135 ILE ILE B . n 
B 2 136 GLU 136 136 136 GLU GLU B . n 
B 2 137 LEU 137 137 137 LEU LEU B . n 
B 2 138 LEU 138 138 138 LEU LEU B . n 
B 2 139 ILE 139 139 139 ILE ILE B . n 
B 2 140 ILE 140 140 140 ILE ILE B . n 
B 2 141 ARG 141 141 141 ARG ARG B . n 
B 2 142 PRO 142 142 142 PRO PRO B . n 
B 2 143 SER 143 143 143 SER SER B . n 
B 2 144 SER 144 144 144 SER SER B . n 
B 2 145 GLN 145 145 145 GLN GLN B . n 
B 2 146 TYR 146 146 146 TYR TYR B . n 
B 2 147 ILE 147 147 147 ILE ILE B . n 
B 2 148 VAL 148 148 148 VAL VAL B . n 
B 2 149 ALA 149 149 149 ALA ALA B . n 
B 2 150 LEU 150 150 150 LEU LEU B . n 
B 2 151 VAL 151 151 151 VAL VAL B . n 
B 2 152 PHE 152 152 152 PHE PHE B . n 
B 2 153 ALA 153 153 153 ALA ALA B . n 
B 2 154 THR 154 154 154 THR THR B . n 
B 2 155 TYR 155 155 155 TYR TYR B . n 
B 2 156 LEU 156 156 156 LEU LEU B . n 
B 2 157 LEU 157 157 157 LEU LEU B . n 
B 2 158 LYS 158 158 158 LYS LYS B . n 
B 2 159 PRO 159 159 159 PRO PRO B . n 
B 2 160 LEU 160 160 160 LEU LEU B . n 
B 2 161 PHE 161 161 161 PHE PHE B . n 
B 2 162 PRO 162 162 162 PRO PRO B . n 
B 2 163 THR 163 163 163 THR THR B . n 
B 2 164 CYS 164 164 164 CYS CYS B . n 
B 2 165 PRO 165 165 165 PRO PRO B . n 
B 2 166 VAL 166 166 166 VAL VAL B . n 
B 2 167 PRO 167 167 167 PRO PRO B . n 
B 2 168 GLU 168 168 168 GLU GLU B . n 
B 2 169 GLU 169 169 169 GLU GLU B . n 
B 2 170 ALA 170 170 170 ALA ALA B . n 
B 2 171 ALA 171 171 171 ALA ALA B . n 
B 2 172 LYS 172 172 172 LYS LYS B . n 
B 2 173 LEU 173 173 173 LEU LEU B . n 
B 2 174 VAL 174 174 174 VAL VAL B . n 
B 2 175 ALA 175 175 175 ALA ALA B . n 
B 2 176 CYS 176 176 176 CYS CYS B . n 
B 2 177 LEU 177 177 177 LEU LEU B . n 
B 2 178 CYS 178 178 178 CYS CYS B . n 
B 2 179 VAL 179 179 179 VAL VAL B . n 
B 2 180 LEU 180 180 180 LEU LEU B . n 
B 2 181 LEU 181 181 181 LEU LEU B . n 
B 2 182 LEU 182 182 182 LEU LEU B . n 
B 2 183 THR 183 183 183 THR THR B . n 
B 2 184 ALA 184 184 184 ALA ALA B . n 
B 2 185 VAL 185 185 185 VAL VAL B . n 
B 2 186 ASN 186 186 186 ASN ASN B . n 
B 2 187 CYS 187 187 187 CYS CYS B . n 
B 2 188 TYR 188 188 188 TYR TYR B . n 
B 2 189 SER 189 189 189 SER SER B . n 
B 2 190 VAL 190 190 190 VAL VAL B . n 
B 2 191 LYS 191 191 191 LYS LYS B . n 
B 2 192 ALA 192 192 192 ALA ALA B . n 
B 2 193 ALA 193 193 193 ALA ALA B . n 
B 2 194 THR 194 194 194 THR THR B . n 
B 2 195 ARG 195 195 195 ARG ARG B . n 
B 2 196 VAL 196 196 196 VAL VAL B . n 
B 2 197 GLN 197 197 197 GLN GLN B . n 
B 2 198 ASP 198 198 198 ASP ASP B . n 
B 2 199 ALA 199 199 199 ALA ALA B . n 
B 2 200 PHE 200 200 200 PHE PHE B . n 
B 2 201 ALA 201 201 201 ALA ALA B . n 
B 2 202 ALA 202 202 202 ALA ALA B . n 
B 2 203 ALA 203 203 203 ALA ALA B . n 
B 2 204 LYS 204 204 204 LYS LYS B . n 
B 2 205 LEU 205 205 205 LEU LEU B . n 
B 2 206 LEU 206 206 206 LEU LEU B . n 
B 2 207 ALA 207 207 207 ALA ALA B . n 
B 2 208 LEU 208 208 208 LEU LEU B . n 
B 2 209 ALA 209 209 209 ALA ALA B . n 
B 2 210 LEU 210 210 210 LEU LEU B . n 
B 2 211 ILE 211 211 211 ILE ILE B . n 
B 2 212 ILE 212 212 212 ILE ILE B . n 
B 2 213 LEU 213 213 213 LEU LEU B . n 
B 2 214 LEU 214 214 214 LEU LEU B . n 
B 2 215 GLY 215 215 215 GLY GLY B . n 
B 2 216 PHE 216 216 216 PHE PHE B . n 
B 2 217 VAL 217 217 217 VAL VAL B . n 
B 2 218 GLN 218 218 218 GLN GLN B . n 
B 2 219 ILE 219 219 219 ILE ILE B . n 
B 2 220 GLY 220 220 220 GLY GLY B . n 
B 2 221 LYS 221 221 221 LYS LYS B . n 
B 2 222 GLY 222 222 222 GLY GLY B . n 
B 2 223 ASP 223 223 ?   ?   ?   B . n 
B 2 224 VAL 224 224 ?   ?   ?   B . n 
B 2 225 SER 225 225 ?   ?   ?   B . n 
B 2 226 ASN 226 226 ?   ?   ?   B . n 
B 2 227 LEU 227 227 ?   ?   ?   B . n 
B 2 228 ASP 228 228 ?   ?   ?   B . n 
B 2 229 PRO 229 229 ?   ?   ?   B . n 
B 2 230 ASN 230 230 ?   ?   ?   B . n 
B 2 231 PHE 231 231 ?   ?   ?   B . n 
B 2 232 SER 232 232 ?   ?   ?   B . n 
B 2 233 PHE 233 233 233 PHE PHE B . n 
B 2 234 GLU 234 234 234 GLU GLU B . n 
B 2 235 GLY 235 235 235 GLY GLY B . n 
B 2 236 THR 236 236 236 THR THR B . n 
B 2 237 LYS 237 237 237 LYS LYS B . n 
B 2 238 LEU 238 238 238 LEU LEU B . n 
B 2 239 ASP 239 239 239 ASP ASP B . n 
B 2 240 VAL 240 240 240 VAL VAL B . n 
B 2 241 GLY 241 241 241 GLY GLY B . n 
B 2 242 ASN 242 242 242 ASN ASN B . n 
B 2 243 ILE 243 243 243 ILE ILE B . n 
B 2 244 VAL 244 244 244 VAL VAL B . n 
B 2 245 LEU 245 245 245 LEU LEU B . n 
B 2 246 ALA 246 246 246 ALA ALA B . n 
B 2 247 LEU 247 247 247 LEU LEU B . n 
B 2 248 TYR 248 248 248 TYR TYR B . n 
B 2 249 SER 249 249 249 SER SER B . n 
B 2 250 GLY 250 250 250 GLY GLY B . n 
B 2 251 LEU 251 251 251 LEU LEU B . n 
B 2 252 PHE 252 252 252 PHE PHE B . n 
B 2 253 ALA 253 253 253 ALA ALA B . n 
B 2 254 TYR 254 254 254 TYR TYR B . n 
B 2 255 GLY 255 255 255 GLY GLY B . n 
B 2 256 GLY 256 256 256 GLY GLY B . n 
B 2 257 TRP 257 257 257 TRP TRP B . n 
B 2 258 ASN 258 258 258 ASN ASN B . n 
B 2 259 TYR 259 259 259 TYR TYR B . n 
B 2 260 LEU 260 260 260 LEU LEU B . n 
B 2 261 ASN 261 261 261 ASN ASN B . n 
B 2 262 PHE 262 262 262 PHE PHE B . n 
B 2 263 VAL 263 263 263 VAL VAL B . n 
B 2 264 THR 264 264 264 THR THR B . n 
B 2 265 GLU 265 265 265 GLU GLU B . n 
B 2 266 GLU 266 266 266 GLU GLU B . n 
B 2 267 MET 267 267 267 MET MET B . n 
B 2 268 ILE 268 268 268 ILE ILE B . n 
B 2 269 ASN 269 269 269 ASN ASN B . n 
B 2 270 PRO 270 270 270 PRO PRO B . n 
B 2 271 TYR 271 271 271 TYR TYR B . n 
B 2 272 ARG 272 272 272 ARG ARG B . n 
B 2 273 ASN 273 273 273 ASN ASN B . n 
B 2 274 LEU 274 274 274 LEU LEU B . n 
B 2 275 PRO 275 275 275 PRO PRO B . n 
B 2 276 LEU 276 276 276 LEU LEU B . n 
B 2 277 ALA 277 277 277 ALA ALA B . n 
B 2 278 ILE 278 278 278 ILE ILE B . n 
B 2 279 ILE 279 279 279 ILE ILE B . n 
B 2 280 ILE 280 280 280 ILE ILE B . n 
B 2 281 SER 281 281 281 SER SER B . n 
B 2 282 LEU 282 282 282 LEU LEU B . n 
B 2 283 PRO 283 283 283 PRO PRO B . n 
B 2 284 ILE 284 284 284 ILE ILE B . n 
B 2 285 VAL 285 285 285 VAL VAL B . n 
B 2 286 THR 286 286 286 THR THR B . n 
B 2 287 LEU 287 287 287 LEU LEU B . n 
B 2 288 VAL 288 288 288 VAL VAL B . n 
B 2 289 TYR 289 289 289 TYR TYR B . n 
B 2 290 VAL 290 290 290 VAL VAL B . n 
B 2 291 LEU 291 291 291 LEU LEU B . n 
B 2 292 THR 292 292 292 THR THR B . n 
B 2 293 ASN 293 293 293 ASN ASN B . n 
B 2 294 LEU 294 294 294 LEU LEU B . n 
B 2 295 ALA 295 295 295 ALA ALA B . n 
B 2 296 TYR 296 296 296 TYR TYR B . n 
B 2 297 PHE 297 297 297 PHE PHE B . n 
B 2 298 THR 298 298 298 THR THR B . n 
B 2 299 THR 299 299 299 THR THR B . n 
B 2 300 LEU 300 300 300 LEU LEU B . n 
B 2 301 SER 301 301 301 SER SER B . n 
B 2 302 THR 302 302 302 THR THR B . n 
B 2 303 GLU 303 303 303 GLU GLU B . n 
B 2 304 GLN 304 304 304 GLN GLN B . n 
B 2 305 MET 305 305 305 MET MET B . n 
B 2 306 LEU 306 306 306 LEU LEU B . n 
B 2 307 SER 307 307 307 SER SER B . n 
B 2 308 SER 308 308 308 SER SER B . n 
B 2 309 GLU 309 309 309 GLU GLU B . n 
B 2 310 ALA 310 310 310 ALA ALA B . n 
B 2 311 VAL 311 311 311 VAL VAL B . n 
B 2 312 ALA 312 312 312 ALA ALA B . n 
B 2 313 VAL 313 313 313 VAL VAL B . n 
B 2 314 ASP 314 314 314 ASP ASP B . n 
B 2 315 PHE 315 315 315 PHE PHE B . n 
B 2 316 GLY 316 316 316 GLY GLY B . n 
B 2 317 ASN 317 317 317 ASN ASN B . n 
B 2 318 TYR 318 318 318 TYR TYR B . n 
B 2 319 HIS 319 319 319 HIS HIS B . n 
B 2 320 LEU 320 320 320 LEU LEU B . n 
B 2 321 GLY 321 321 321 GLY GLY B . n 
B 2 322 VAL 322 322 322 VAL VAL B . n 
B 2 323 MET 323 323 323 MET MET B . n 
B 2 324 SER 324 324 324 SER SER B . n 
B 2 325 TRP 325 325 325 TRP TRP B . n 
B 2 326 ILE 326 326 326 ILE ILE B . n 
B 2 327 ILE 327 327 327 ILE ILE B . n 
B 2 328 PRO 328 328 328 PRO PRO B . n 
B 2 329 VAL 329 329 329 VAL VAL B . n 
B 2 330 PHE 330 330 330 PHE PHE B . n 
B 2 331 VAL 331 331 331 VAL VAL B . n 
B 2 332 GLY 332 332 332 GLY GLY B . n 
B 2 333 LEU 333 333 333 LEU LEU B . n 
B 2 334 SER 334 334 334 SER SER B . n 
B 2 335 CYS 335 335 335 CYS CYS B . n 
B 2 336 PHE 336 336 336 PHE PHE B . n 
B 2 337 GLY 337 337 337 GLY GLY B . n 
B 2 338 SER 338 338 338 SER SER B . n 
B 2 339 VAL 339 339 339 VAL VAL B . n 
B 2 340 ASN 340 340 340 ASN ASN B . n 
B 2 341 GLY 341 341 341 GLY GLY B . n 
B 2 342 SER 342 342 342 SER SER B . n 
B 2 343 LEU 343 343 343 LEU LEU B . n 
B 2 344 PHE 344 344 344 PHE PHE B . n 
B 2 345 THR 345 345 345 THR THR B . n 
B 2 346 SER 346 346 346 SER SER B . n 
B 2 347 SER 347 347 347 SER SER B . n 
B 2 348 ARG 348 348 348 ARG ARG B . n 
B 2 349 LEU 349 349 349 LEU LEU B . n 
B 2 350 PHE 350 350 350 PHE PHE B . n 
B 2 351 PHE 351 351 351 PHE PHE B . n 
B 2 352 VAL 352 352 352 VAL VAL B . n 
B 2 353 GLY 353 353 353 GLY GLY B . n 
B 2 354 SER 354 354 354 SER SER B . n 
B 2 355 ARG 355 355 355 ARG ARG B . n 
B 2 356 GLU 356 356 356 GLU GLU B . n 
B 2 357 GLY 357 357 357 GLY GLY B . n 
B 2 358 HIS 358 358 358 HIS HIS B . n 
B 2 359 LEU 359 359 359 LEU LEU B . n 
B 2 360 PRO 360 360 360 PRO PRO B . n 
B 2 361 SER 361 361 361 SER SER B . n 
B 2 362 ILE 362 362 362 ILE ILE B . n 
B 2 363 LEU 363 363 363 LEU LEU B . n 
B 2 364 SER 364 364 364 SER SER B . n 
B 2 365 MET 365 365 365 MET MET B . n 
B 2 366 ILE 366 366 366 ILE ILE B . n 
B 2 367 HIS 367 367 367 HIS HIS B . n 
B 2 368 PRO 368 368 368 PRO PRO B . n 
B 2 369 GLN 369 369 369 GLN GLN B . n 
B 2 370 LEU 370 370 370 LEU LEU B . n 
B 2 371 LEU 371 371 371 LEU LEU B . n 
B 2 372 THR 372 372 372 THR THR B . n 
B 2 373 PRO 373 373 373 PRO PRO B . n 
B 2 374 VAL 374 374 374 VAL VAL B . n 
B 2 375 PRO 375 375 375 PRO PRO B . n 
B 2 376 SER 376 376 376 SER SER B . n 
B 2 377 LEU 377 377 377 LEU LEU B . n 
B 2 378 VAL 378 378 378 VAL VAL B . n 
B 2 379 PHE 379 379 379 PHE PHE B . n 
B 2 380 THR 380 380 380 THR THR B . n 
B 2 381 CYS 381 381 381 CYS CYS B . n 
B 2 382 VAL 382 382 382 VAL VAL B . n 
B 2 383 MET 383 383 383 MET MET B . n 
B 2 384 THR 384 384 384 THR THR B . n 
B 2 385 LEU 385 385 385 LEU LEU B . n 
B 2 386 LEU 386 386 386 LEU LEU B . n 
B 2 387 TYR 387 387 387 TYR TYR B . n 
B 2 388 ALA 388 388 388 ALA ALA B . n 
B 2 389 PHE 389 389 389 PHE PHE B . n 
B 2 390 SER 390 390 390 SER SER B . n 
B 2 391 LYS 391 391 391 LYS LYS B . n 
B 2 392 ASP 392 392 392 ASP ASP B . n 
B 2 393 ILE 393 393 393 ILE ILE B . n 
B 2 394 PHE 394 394 394 PHE PHE B . n 
B 2 395 SER 395 395 395 SER SER B . n 
B 2 396 VAL 396 396 396 VAL VAL B . n 
B 2 397 ILE 397 397 397 ILE ILE B . n 
B 2 398 ASN 398 398 398 ASN ASN B . n 
B 2 399 PHE 399 399 399 PHE PHE B . n 
B 2 400 PHE 400 400 400 PHE PHE B . n 
B 2 401 SER 401 401 401 SER SER B . n 
B 2 402 PHE 402 402 402 PHE PHE B . n 
B 2 403 PHE 403 403 403 PHE PHE B . n 
B 2 404 ASN 404 404 404 ASN ASN B . n 
B 2 405 TRP 405 405 405 TRP TRP B . n 
B 2 406 LEU 406 406 406 LEU LEU B . n 
B 2 407 CYS 407 407 407 CYS CYS B . n 
B 2 408 VAL 408 408 408 VAL VAL B . n 
B 2 409 ALA 409 409 409 ALA ALA B . n 
B 2 410 LEU 410 410 410 LEU LEU B . n 
B 2 411 ALA 411 411 411 ALA ALA B . n 
B 2 412 ILE 412 412 412 ILE ILE B . n 
B 2 413 ILE 413 413 413 ILE ILE B . n 
B 2 414 GLY 414 414 414 GLY GLY B . n 
B 2 415 MET 415 415 415 MET MET B . n 
B 2 416 ILE 416 416 416 ILE ILE B . n 
B 2 417 TRP 417 417 417 TRP TRP B . n 
B 2 418 LEU 418 418 418 LEU LEU B . n 
B 2 419 ARG 419 419 419 ARG ARG B . n 
B 2 420 HIS 420 420 420 HIS HIS B . n 
B 2 421 ARG 421 421 421 ARG ARG B . n 
B 2 422 LYS 422 422 422 LYS LYS B . n 
B 2 423 PRO 423 423 423 PRO PRO B . n 
B 2 424 GLU 424 424 424 GLU GLU B . n 
B 2 425 LEU 425 425 425 LEU LEU B . n 
B 2 426 GLU 426 426 426 GLU GLU B . n 
B 2 427 ARG 427 427 427 ARG ARG B . n 
B 2 428 PRO 428 428 428 PRO PRO B . n 
B 2 429 ILE 429 429 429 ILE ILE B . n 
B 2 430 LYS 430 430 430 LYS LYS B . n 
B 2 431 VAL 431 431 431 VAL VAL B . n 
B 2 432 ASN 432 432 432 ASN ASN B . n 
B 2 433 LEU 433 433 433 LEU LEU B . n 
B 2 434 ALA 434 434 434 ALA ALA B . n 
B 2 435 LEU 435 435 435 LEU LEU B . n 
B 2 436 PRO 436 436 436 PRO PRO B . n 
B 2 437 VAL 437 437 437 VAL VAL B . n 
B 2 438 PHE 438 438 438 PHE PHE B . n 
B 2 439 PHE 439 439 439 PHE PHE B . n 
B 2 440 ILE 440 440 440 ILE ILE B . n 
B 2 441 LEU 441 441 441 LEU LEU B . n 
B 2 442 ALA 442 442 442 ALA ALA B . n 
B 2 443 CYS 443 443 443 CYS CYS B . n 
B 2 444 LEU 444 444 444 LEU LEU B . n 
B 2 445 PHE 445 445 445 PHE PHE B . n 
B 2 446 LEU 446 446 446 LEU LEU B . n 
B 2 447 ILE 447 447 447 ILE ILE B . n 
B 2 448 ALA 448 448 448 ALA ALA B . n 
B 2 449 VAL 449 449 449 VAL VAL B . n 
B 2 450 SER 450 450 450 SER SER B . n 
B 2 451 PHE 451 451 451 PHE PHE B . n 
B 2 452 TRP 452 452 452 TRP TRP B . n 
B 2 453 LYS 453 453 453 LYS LYS B . n 
B 2 454 THR 454 454 454 THR THR B . n 
B 2 455 PRO 455 455 455 PRO PRO B . n 
B 2 456 VAL 456 456 456 VAL VAL B . n 
B 2 457 GLU 457 457 457 GLU GLU B . n 
B 2 458 CYS 458 458 458 CYS CYS B . n 
B 2 459 GLY 459 459 459 GLY GLY B . n 
B 2 460 ILE 460 460 460 ILE ILE B . n 
B 2 461 GLY 461 461 461 GLY GLY B . n 
B 2 462 PHE 462 462 462 PHE PHE B . n 
B 2 463 THR 463 463 463 THR THR B . n 
B 2 464 ILE 464 464 464 ILE ILE B . n 
B 2 465 ILE 465 465 465 ILE ILE B . n 
B 2 466 LEU 466 466 466 LEU LEU B . n 
B 2 467 SER 467 467 467 SER SER B . n 
B 2 468 GLY 468 468 468 GLY GLY B . n 
B 2 469 LEU 469 469 469 LEU LEU B . n 
B 2 470 PRO 470 470 470 PRO PRO B . n 
B 2 471 VAL 471 471 471 VAL VAL B . n 
B 2 472 TYR 472 472 472 TYR TYR B . n 
B 2 473 PHE 473 473 473 PHE PHE B . n 
B 2 474 PHE 474 474 474 PHE PHE B . n 
B 2 475 GLY 475 475 475 GLY GLY B . n 
B 2 476 VAL 476 476 476 VAL VAL B . n 
B 2 477 TRP 477 477 477 TRP TRP B . n 
B 2 478 TRP 478 478 478 TRP TRP B . n 
B 2 479 LYS 479 479 479 LYS LYS B . n 
B 2 480 ASN 480 480 480 ASN ASN B . n 
B 2 481 LYS 481 481 481 LYS LYS B . n 
B 2 482 PRO 482 482 482 PRO PRO B . n 
B 2 483 LYS 483 483 483 LYS LYS B . n 
B 2 484 TRP 484 484 484 TRP TRP B . n 
B 2 485 LEU 485 485 485 LEU LEU B . n 
B 2 486 LEU 486 486 486 LEU LEU B . n 
B 2 487 GLN 487 487 487 GLN GLN B . n 
B 2 488 GLY 488 488 488 GLY GLY B . n 
B 2 489 ILE 489 489 489 ILE ILE B . n 
B 2 490 PHE 490 490 490 PHE PHE B . n 
B 2 491 SER 491 491 491 SER SER B . n 
B 2 492 THR 492 492 492 THR THR B . n 
B 2 493 THR 493 493 493 THR THR B . n 
B 2 494 VAL 494 494 494 VAL VAL B . n 
B 2 495 LEU 495 495 495 LEU LEU B . n 
B 2 496 CYS 496 496 496 CYS CYS B . n 
B 2 497 GLN 497 497 497 GLN GLN B . n 
B 2 498 LYS 498 498 498 LYS LYS B . n 
B 2 499 LEU 499 499 499 LEU LEU B . n 
B 2 500 MET 500 500 500 MET MET B . n 
B 2 501 GLN 501 501 501 GLN GLN B . n 
B 2 502 VAL 502 502 502 VAL VAL B . n 
B 2 503 VAL 503 503 503 VAL VAL B . n 
B 2 504 PRO 504 504 504 PRO PRO B . n 
B 2 505 GLN 505 505 505 GLN GLN B . n 
B 2 506 GLU 506 506 506 GLU GLU B . n 
B 2 507 THR 507 507 507 THR THR B . n 
B 2 508 ASP 508 508 ?   ?   ?   B . n 
B 2 509 TYR 509 509 ?   ?   ?   B . n 
B 2 510 LYS 510 510 ?   ?   ?   B . n 
B 2 511 ASP 511 511 ?   ?   ?   B . n 
B 2 512 ASP 512 512 ?   ?   ?   B . n 
B 2 513 ASP 513 513 ?   ?   ?   B . n 
B 2 514 ASP 514 514 ?   ?   ?   B . n 
B 2 515 LYS 515 515 ?   ?   ?   B . n 
C 3 1   ASP 1   1   1   ASP ASP L . n 
C 3 2   ILE 2   2   2   ILE ILE L . n 
C 3 3   VAL 3   3   3   VAL VAL L . n 
C 3 4   LEU 4   4   4   LEU LEU L . n 
C 3 5   THR 5   5   5   THR THR L . n 
C 3 6   GLN 6   6   6   GLN GLN L . n 
C 3 7   SER 7   7   7   SER SER L . n 
C 3 8   PRO 8   8   8   PRO PRO L . n 
C 3 9   SER 9   9   9   SER SER L . n 
C 3 10  SER 10  10  10  SER SER L . n 
C 3 11  LEU 11  11  11  LEU LEU L . n 
C 3 12  ALA 12  12  12  ALA ALA L . n 
C 3 13  MET 13  13  13  MET MET L . n 
C 3 14  SER 14  14  14  SER SER L . n 
C 3 15  VAL 15  15  15  VAL VAL L . n 
C 3 16  GLY 16  16  16  GLY GLY L . n 
C 3 17  GLN 17  17  17  GLN GLN L . n 
C 3 18  LYS 18  18  18  LYS LYS L . n 
C 3 19  VAL 19  19  19  VAL VAL L . n 
C 3 20  THR 20  20  20  THR THR L . n 
C 3 21  MET 21  21  21  MET MET L . n 
C 3 22  ASN 22  22  22  ASN ASN L . n 
C 3 23  CYS 23  23  23  CYS CYS L . n 
C 3 24  LYS 24  24  24  LYS LYS L . n 
C 3 25  SER 25  25  25  SER SER L . n 
C 3 26  SER 26  26  26  SER SER L . n 
C 3 27  GLN 27  27  27  GLN GLN L . n 
C 3 28  SER 28  28  28  SER SER L . n 
C 3 29  LEU 29  29  29  LEU LEU L . n 
C 3 30  LEU 30  30  30  LEU LEU L . n 
C 3 31  ASN 31  31  31  ASN ASN L . n 
C 3 32  ASN 32  32  32  ASN ASN L . n 
C 3 33  ASN 33  33  33  ASN ASN L . n 
C 3 34  ASN 34  34  34  ASN ASN L . n 
C 3 35  GLN 35  35  35  GLN GLN L . n 
C 3 36  LYS 36  36  36  LYS LYS L . n 
C 3 37  ASN 37  37  37  ASN ASN L . n 
C 3 38  TYR 38  38  38  TYR TYR L . n 
C 3 39  LEU 39  39  39  LEU LEU L . n 
C 3 40  ALA 40  40  40  ALA ALA L . n 
C 3 41  TRP 41  41  41  TRP TRP L . n 
C 3 42  TYR 42  42  42  TYR TYR L . n 
C 3 43  GLN 43  43  43  GLN GLN L . n 
C 3 44  GLN 44  44  44  GLN GLN L . n 
C 3 45  LYS 45  45  45  LYS LYS L . n 
C 3 46  PRO 46  46  46  PRO PRO L . n 
C 3 47  GLY 47  47  47  GLY GLY L . n 
C 3 48  GLN 48  48  48  GLN GLN L . n 
C 3 49  SER 49  49  49  SER SER L . n 
C 3 50  PRO 50  50  50  PRO PRO L . n 
C 3 51  LYS 51  51  51  LYS LYS L . n 
C 3 52  LEU 52  52  52  LEU LEU L . n 
C 3 53  LEU 53  53  53  LEU LEU L . n 
C 3 54  VAL 54  54  54  VAL VAL L . n 
C 3 55  TYR 55  55  55  TYR TYR L . n 
C 3 56  PHE 56  56  56  PHE PHE L . n 
C 3 57  THR 57  57  57  THR THR L . n 
C 3 58  SER 58  58  58  SER SER L . n 
C 3 59  THR 59  59  59  THR THR L . n 
C 3 60  ARG 60  60  60  ARG ARG L . n 
C 3 61  GLU 61  61  61  GLU GLU L . n 
C 3 62  SER 62  62  62  SER SER L . n 
C 3 63  GLY 63  63  63  GLY GLY L . n 
C 3 64  VAL 64  64  64  VAL VAL L . n 
C 3 65  PRO 65  65  65  PRO PRO L . n 
C 3 66  ASP 66  66  66  ASP ASP L . n 
C 3 67  ARG 67  67  67  ARG ARG L . n 
C 3 68  PHE 68  68  68  PHE PHE L . n 
C 3 69  ILE 69  69  69  ILE ILE L . n 
C 3 70  GLY 70  70  70  GLY GLY L . n 
C 3 71  SER 71  71  71  SER SER L . n 
C 3 72  GLY 72  72  72  GLY GLY L . n 
C 3 73  SER 73  73  73  SER SER L . n 
C 3 74  GLY 74  74  74  GLY GLY L . n 
C 3 75  THR 75  75  75  THR THR L . n 
C 3 76  ASP 76  76  76  ASP ASP L . n 
C 3 77  PHE 77  77  77  PHE PHE L . n 
C 3 78  THR 78  78  78  THR THR L . n 
C 3 79  LEU 79  79  79  LEU LEU L . n 
C 3 80  THR 80  80  80  THR THR L . n 
C 3 81  ILE 81  81  81  ILE ILE L . n 
C 3 82  SER 82  82  82  SER SER L . n 
C 3 83  SER 83  83  83  SER SER L . n 
C 3 84  VAL 84  84  84  VAL VAL L . n 
C 3 85  GLN 85  85  85  GLN GLN L . n 
C 3 86  ALA 86  86  86  ALA ALA L . n 
C 3 87  GLU 87  87  87  GLU GLU L . n 
C 3 88  ASP 88  88  88  ASP ASP L . n 
C 3 89  LEU 89  89  89  LEU LEU L . n 
C 3 90  ALA 90  90  90  ALA ALA L . n 
C 3 91  LEU 91  91  91  LEU LEU L . n 
C 3 92  TYR 92  92  92  TYR TYR L . n 
C 3 93  TYR 93  93  93  TYR TYR L . n 
C 3 94  CYS 94  94  94  CYS CYS L . n 
C 3 95  GLN 95  95  95  GLN GLN L . n 
C 3 96  GLN 96  96  96  GLN GLN L . n 
C 3 97  HIS 97  97  97  HIS HIS L . n 
C 3 98  TYR 98  98  98  TYR TYR L . n 
C 3 99  THR 99  99  99  THR THR L . n 
C 3 100 ILE 100 100 100 ILE ILE L . n 
C 3 101 PRO 101 101 101 PRO PRO L . n 
C 3 102 PRO 102 102 102 PRO PRO L . n 
C 3 103 THR 103 103 103 THR THR L . n 
C 3 104 PHE 104 104 104 PHE PHE L . n 
C 3 105 GLY 105 105 105 GLY GLY L . n 
C 3 106 GLY 106 106 106 GLY GLY L . n 
C 3 107 GLY 107 107 107 GLY GLY L . n 
C 3 108 THR 108 108 108 THR THR L . n 
C 3 109 LYS 109 109 109 LYS LYS L . n 
C 3 110 LEU 110 110 110 LEU LEU L . n 
C 3 111 GLU 111 111 111 GLU GLU L . n 
C 3 112 ILE 112 112 112 ILE ILE L . n 
C 3 113 LYS 113 113 113 LYS LYS L . n 
C 3 114 ARG 114 114 114 ARG ARG L . n 
C 3 115 ALA 115 115 115 ALA ALA L . n 
C 3 116 ASP 116 116 116 ASP ASP L . n 
C 3 117 ALA 117 117 117 ALA ALA L . n 
C 3 118 ALA 118 118 118 ALA ALA L . n 
C 3 119 PRO 119 119 119 PRO PRO L . n 
C 3 120 THR 120 120 120 THR THR L . n 
C 3 121 VAL 121 121 121 VAL VAL L . n 
C 3 122 SER 122 122 122 SER SER L . n 
C 3 123 ILE 123 123 123 ILE ILE L . n 
C 3 124 PHE 124 124 124 PHE PHE L . n 
C 3 125 PRO 125 125 125 PRO PRO L . n 
C 3 126 PRO 126 126 126 PRO PRO L . n 
C 3 127 SER 127 127 127 SER SER L . n 
C 3 128 SER 128 128 128 SER SER L . n 
C 3 129 GLU 129 129 129 GLU GLU L . n 
C 3 130 GLN 130 130 130 GLN GLN L . n 
C 3 131 LEU 131 131 131 LEU LEU L . n 
C 3 132 THR 132 132 132 THR THR L . n 
C 3 133 SER 133 133 133 SER SER L . n 
C 3 134 GLY 134 134 134 GLY GLY L . n 
C 3 135 GLY 135 135 135 GLY GLY L . n 
C 3 136 ALA 136 136 136 ALA ALA L . n 
C 3 137 SER 137 137 137 SER SER L . n 
C 3 138 VAL 138 138 138 VAL VAL L . n 
C 3 139 VAL 139 139 139 VAL VAL L . n 
C 3 140 CYS 140 140 140 CYS CYS L . n 
C 3 141 PHE 141 141 141 PHE PHE L . n 
C 3 142 LEU 142 142 142 LEU LEU L . n 
C 3 143 ASN 143 143 143 ASN ASN L . n 
C 3 144 ASN 144 144 144 ASN ASN L . n 
C 3 145 PHE 145 145 145 PHE PHE L . n 
C 3 146 TYR 146 146 146 TYR TYR L . n 
C 3 147 PRO 147 147 147 PRO PRO L . n 
C 3 148 LYS 148 148 148 LYS LYS L . n 
C 3 149 ASP 149 149 149 ASP ASP L . n 
C 3 150 ILE 150 150 150 ILE ILE L . n 
C 3 151 ASN 151 151 151 ASN ASN L . n 
C 3 152 VAL 152 152 152 VAL VAL L . n 
C 3 153 LYS 153 153 153 LYS LYS L . n 
C 3 154 TRP 154 154 154 TRP TRP L . n 
C 3 155 LYS 155 155 155 LYS LYS L . n 
C 3 156 ILE 156 156 156 ILE ILE L . n 
C 3 157 ASP 157 157 157 ASP ASP L . n 
C 3 158 GLY 158 158 158 GLY GLY L . n 
C 3 159 SER 159 159 159 SER SER L . n 
C 3 160 GLU 160 160 160 GLU GLU L . n 
C 3 161 ARG 161 161 161 ARG ARG L . n 
C 3 162 GLN 162 162 162 GLN GLN L . n 
C 3 163 ASN 163 163 163 ASN ASN L . n 
C 3 164 GLY 164 164 164 GLY GLY L . n 
C 3 165 VAL 165 165 165 VAL VAL L . n 
C 3 166 LEU 166 166 166 LEU LEU L . n 
C 3 167 ASN 167 167 167 ASN ASN L . n 
C 3 168 SER 168 168 168 SER SER L . n 
C 3 169 TRP 169 169 169 TRP TRP L . n 
C 3 170 THR 170 170 170 THR THR L . n 
C 3 171 ASP 171 171 171 ASP ASP L . n 
C 3 172 GLN 172 172 172 GLN GLN L . n 
C 3 173 ASP 173 173 173 ASP ASP L . n 
C 3 174 SER 174 174 174 SER SER L . n 
C 3 175 LYS 175 175 175 LYS LYS L . n 
C 3 176 ASP 176 176 176 ASP ASP L . n 
C 3 177 SER 177 177 177 SER SER L . n 
C 3 178 THR 178 178 178 THR THR L . n 
C 3 179 TYR 179 179 179 TYR TYR L . n 
C 3 180 SER 180 180 180 SER SER L . n 
C 3 181 MET 181 181 181 MET MET L . n 
C 3 182 SER 182 182 182 SER SER L . n 
C 3 183 SER 183 183 183 SER SER L . n 
C 3 184 THR 184 184 184 THR THR L . n 
C 3 185 LEU 185 185 185 LEU LEU L . n 
C 3 186 THR 186 186 186 THR THR L . n 
C 3 187 LEU 187 187 187 LEU LEU L . n 
C 3 188 THR 188 188 188 THR THR L . n 
C 3 189 LYS 189 189 189 LYS LYS L . n 
C 3 190 ASP 190 190 190 ASP ASP L . n 
C 3 191 GLU 191 191 191 GLU GLU L . n 
C 3 192 TYR 192 192 192 TYR TYR L . n 
C 3 193 GLU 193 193 193 GLU GLU L . n 
C 3 194 ARG 194 194 194 ARG ARG L . n 
C 3 195 HIS 195 195 195 HIS HIS L . n 
C 3 196 ASN 196 196 196 ASN ASN L . n 
C 3 197 SER 197 197 197 SER SER L . n 
C 3 198 TYR 198 198 198 TYR TYR L . n 
C 3 199 THR 199 199 199 THR THR L . n 
C 3 200 CYS 200 200 200 CYS CYS L . n 
C 3 201 GLU 201 201 201 GLU GLU L . n 
C 3 202 ALA 202 202 202 ALA ALA L . n 
C 3 203 THR 203 203 203 THR THR L . n 
C 3 204 HIS 204 204 204 HIS HIS L . n 
C 3 205 LYS 205 205 205 LYS LYS L . n 
C 3 206 THR 206 206 206 THR THR L . n 
C 3 207 SER 207 207 207 SER SER L . n 
C 3 208 THR 208 208 208 THR THR L . n 
C 3 209 SER 209 209 209 SER SER L . n 
C 3 210 PRO 210 210 210 PRO PRO L . n 
C 3 211 ILE 211 211 211 ILE ILE L . n 
C 3 212 VAL 212 212 212 VAL VAL L . n 
C 3 213 LYS 213 213 213 LYS LYS L . n 
C 3 214 SER 214 214 214 SER SER L . n 
C 3 215 PHE 215 215 215 PHE PHE L . n 
C 3 216 ASN 216 216 216 ASN ASN L . n 
C 3 217 ARG 217 217 217 ARG ARG L . n 
C 3 218 ASN 218 218 ?   ?   ?   L . n 
C 3 219 GLU 219 219 ?   ?   ?   L . n 
C 3 220 CYS 220 220 ?   ?   ?   L . n 
D 4 1   GLU 1   1   1   GLU GLU H . n 
D 4 2   VAL 2   2   2   VAL VAL H . n 
D 4 3   GLN 3   3   3   GLN GLN H . n 
D 4 4   LEU 4   4   4   LEU LEU H . n 
D 4 5   GLN 5   5   5   GLN GLN H . n 
D 4 6   GLN 6   6   6   GLN GLN H . n 
D 4 7   SER 7   7   7   SER SER H . n 
D 4 8   GLY 8   8   8   GLY GLY H . n 
D 4 9   ALA 9   9   9   ALA ALA H . n 
D 4 10  GLU 10  10  10  GLU GLU H . n 
D 4 11  LEU 11  11  11  LEU LEU H . n 
D 4 12  VAL 12  12  12  VAL VAL H . n 
D 4 13  LYS 13  13  13  LYS LYS H . n 
D 4 14  PRO 14  14  14  PRO PRO H . n 
D 4 15  GLY 15  15  15  GLY GLY H . n 
D 4 16  ALA 16  16  16  ALA ALA H . n 
D 4 17  SER 17  17  17  SER SER H . n 
D 4 18  VAL 18  18  18  VAL VAL H . n 
D 4 19  ASN 19  19  19  ASN ASN H . n 
D 4 20  LEU 20  20  20  LEU LEU H . n 
D 4 21  SER 21  21  21  SER SER H . n 
D 4 22  CYS 22  22  22  CYS CYS H . n 
D 4 23  LYS 23  23  23  LYS LYS H . n 
D 4 24  ALA 24  24  24  ALA ALA H . n 
D 4 25  SER 25  25  25  SER SER H . n 
D 4 26  GLY 26  26  26  GLY GLY H . n 
D 4 27  TYR 27  27  27  TYR TYR H . n 
D 4 28  THR 28  28  28  THR THR H . n 
D 4 29  PHE 29  29  29  PHE PHE H . n 
D 4 30  THR 30  30  30  THR THR H . n 
D 4 31  ASN 31  31  31  ASN ASN H . n 
D 4 32  TYR 32  32  32  TYR TYR H . n 
D 4 33  TRP 33  33  33  TRP TRP H . n 
D 4 34  MET 34  34  34  MET MET H . n 
D 4 35  HIS 35  35  35  HIS HIS H . n 
D 4 36  TRP 36  36  36  TRP TRP H . n 
D 4 37  VAL 37  37  37  VAL VAL H . n 
D 4 38  ARG 38  38  38  ARG ARG H . n 
D 4 39  LEU 39  39  39  LEU LEU H . n 
D 4 40  ARG 40  40  40  ARG ARG H . n 
D 4 41  PRO 41  41  41  PRO PRO H . n 
D 4 42  GLY 42  42  42  GLY GLY H . n 
D 4 43  GLN 43  43  43  GLN GLN H . n 
D 4 44  GLY 44  44  44  GLY GLY H . n 
D 4 45  LEU 45  45  45  LEU LEU H . n 
D 4 46  GLU 46  46  46  GLU GLU H . n 
D 4 47  TRP 47  47  47  TRP TRP H . n 
D 4 48  ILE 48  48  48  ILE ILE H . n 
D 4 49  GLY 49  49  49  GLY GLY H . n 
D 4 50  GLU 50  50  50  GLU GLU H . n 
D 4 51  ILE 51  51  51  ILE ILE H . n 
D 4 52  ASP 52  52  52  ASP ASP H . n 
D 4 53  PRO 53  53  53  PRO PRO H . n 
D 4 54  SER 54  54  54  SER SER H . n 
D 4 55  ASP 55  55  55  ASP ASP H . n 
D 4 56  SER 56  56  56  SER SER H . n 
D 4 57  TYR 57  57  57  TYR TYR H . n 
D 4 58  SER 58  58  58  SER SER H . n 
D 4 59  TYR 59  59  59  TYR TYR H . n 
D 4 60  TYR 60  60  60  TYR TYR H . n 
D 4 61  SER 61  61  61  SER SER H . n 
D 4 62  GLN 62  62  62  GLN GLN H . n 
D 4 63  ASN 63  63  63  ASN ASN H . n 
D 4 64  PHE 64  64  64  PHE PHE H . n 
D 4 65  LYS 65  65  65  LYS LYS H . n 
D 4 66  GLY 66  66  66  GLY GLY H . n 
D 4 67  LYS 67  67  67  LYS LYS H . n 
D 4 68  ALA 68  68  68  ALA ALA H . n 
D 4 69  THR 69  69  69  THR THR H . n 
D 4 70  LEU 70  70  70  LEU LEU H . n 
D 4 71  THR 71  71  71  THR THR H . n 
D 4 72  VAL 72  72  72  VAL VAL H . n 
D 4 73  ASP 73  73  73  ASP ASP H . n 
D 4 74  GLN 74  74  74  GLN GLN H . n 
D 4 75  SER 75  75  75  SER SER H . n 
D 4 76  SER 76  76  76  SER SER H . n 
D 4 77  ASN 77  77  77  ASN ASN H . n 
D 4 78  THR 78  78  78  THR THR H . n 
D 4 79  ALA 79  79  79  ALA ALA H . n 
D 4 80  TYR 80  80  80  TYR TYR H . n 
D 4 81  LEU 81  81  81  LEU LEU H . n 
D 4 82  GLN 82  82  82  GLN GLN H . n 
D 4 83  LEU 83  83  83  LEU LEU H . n 
D 4 84  THR 84  84  84  THR THR H . n 
D 4 85  SER 85  85  85  SER SER H . n 
D 4 86  LEU 86  86  86  LEU LEU H . n 
D 4 87  THR 87  87  87  THR THR H . n 
D 4 88  SER 88  88  88  SER SER H . n 
D 4 89  GLU 89  89  89  GLU GLU H . n 
D 4 90  ASP 90  90  90  ASP ASP H . n 
D 4 91  SER 91  91  91  SER SER H . n 
D 4 92  ALA 92  92  92  ALA ALA H . n 
D 4 93  VAL 93  93  93  VAL VAL H . n 
D 4 94  TYR 94  94  94  TYR TYR H . n 
D 4 95  TYR 95  95  95  TYR TYR H . n 
D 4 96  CYS 96  96  96  CYS CYS H . n 
D 4 97  ALA 97  97  97  ALA ALA H . n 
D 4 98  ARG 98  98  98  ARG ARG H . n 
D 4 99  GLY 99  99  99  GLY GLY H . n 
D 4 100 ARG 100 100 100 ARG ARG H . n 
D 4 101 GLN 101 101 101 GLN GLN H . n 
D 4 102 THR 102 102 102 THR THR H . n 
D 4 103 TYR 103 103 103 TYR TYR H . n 
D 4 104 TYR 104 104 104 TYR TYR H . n 
D 4 105 PRO 105 105 105 PRO PRO H . n 
D 4 106 TRP 106 106 106 TRP TRP H . n 
D 4 107 PHE 107 107 107 PHE PHE H . n 
D 4 108 PRO 108 108 108 PRO PRO H . n 
D 4 109 TYR 109 109 109 TYR TYR H . n 
D 4 110 TRP 110 110 110 TRP TRP H . n 
D 4 111 GLY 111 111 111 GLY GLY H . n 
D 4 112 GLN 112 112 112 GLN GLN H . n 
D 4 113 GLY 113 113 113 GLY GLY H . n 
D 4 114 THR 114 114 114 THR THR H . n 
D 4 115 LEU 115 115 115 LEU LEU H . n 
D 4 116 VAL 116 116 116 VAL VAL H . n 
D 4 117 THR 117 117 117 THR THR H . n 
D 4 118 VAL 118 118 118 VAL VAL H . n 
D 4 119 SER 119 119 119 SER SER H . n 
D 4 120 ALA 120 120 120 ALA ALA H . n 
D 4 121 ALA 121 121 121 ALA ALA H . n 
D 4 122 LYS 122 122 122 LYS LYS H . n 
D 4 123 THR 123 123 123 THR THR H . n 
D 4 124 THR 124 124 124 THR THR H . n 
D 4 125 PRO 125 125 125 PRO PRO H . n 
D 4 126 PRO 126 126 126 PRO PRO H . n 
D 4 127 SER 127 127 127 SER SER H . n 
D 4 128 ASP 128 128 128 ASP ASP H . n 
D 4 129 TYR 129 129 129 TYR TYR H . n 
D 4 130 PRO 130 130 130 PRO PRO H . n 
D 4 131 LEU 131 131 131 LEU LEU H . n 
D 4 132 ALA 132 132 132 ALA ALA H . n 
D 4 133 PRO 133 133 133 PRO PRO H . n 
D 4 134 GLY 134 134 134 GLY GLY H . n 
D 4 135 SER 135 135 135 SER SER H . n 
D 4 136 ALA 136 136 136 ALA ALA H . n 
D 4 137 ALA 137 137 137 ALA ALA H . n 
D 4 138 GLN 138 138 138 GLN GLN H . n 
D 4 139 THR 139 139 139 THR THR H . n 
D 4 140 ASN 140 140 140 ASN ASN H . n 
D 4 141 SER 141 141 141 SER SER H . n 
D 4 142 MET 142 142 142 MET MET H . n 
D 4 143 VAL 143 143 143 VAL VAL H . n 
D 4 144 THR 144 144 144 THR THR H . n 
D 4 145 LEU 145 145 145 LEU LEU H . n 
D 4 146 GLY 146 146 146 GLY GLY H . n 
D 4 147 CYS 147 147 147 CYS CYS H . n 
D 4 148 LEU 148 148 148 LEU LEU H . n 
D 4 149 VAL 149 149 149 VAL VAL H . n 
D 4 150 LYS 150 150 150 LYS LYS H . n 
D 4 151 GLY 151 151 151 GLY GLY H . n 
D 4 152 TYR 152 152 152 TYR TYR H . n 
D 4 153 PHE 153 153 153 PHE PHE H . n 
D 4 154 PRO 154 154 154 PRO PRO H . n 
D 4 155 GLU 155 155 155 GLU GLU H . n 
D 4 156 PRO 156 156 156 PRO PRO H . n 
D 4 157 VAL 157 157 157 VAL VAL H . n 
D 4 158 THR 158 158 158 THR THR H . n 
D 4 159 VAL 159 159 159 VAL VAL H . n 
D 4 160 THR 160 160 160 THR THR H . n 
D 4 161 TRP 161 161 161 TRP TRP H . n 
D 4 162 ASN 162 162 162 ASN ASN H . n 
D 4 163 SER 163 163 163 SER SER H . n 
D 4 164 GLY 164 164 164 GLY GLY H . n 
D 4 165 SER 165 165 165 SER SER H . n 
D 4 166 LEU 166 166 166 LEU LEU H . n 
D 4 167 SER 167 167 167 SER SER H . n 
D 4 168 SER 168 168 168 SER SER H . n 
D 4 169 GLY 169 169 169 GLY GLY H . n 
D 4 170 VAL 170 170 170 VAL VAL H . n 
D 4 171 HIS 171 171 171 HIS HIS H . n 
D 4 172 THR 172 172 172 THR THR H . n 
D 4 173 PHE 173 173 173 PHE PHE H . n 
D 4 174 PRO 174 174 174 PRO PRO H . n 
D 4 175 ALA 175 175 175 ALA ALA H . n 
D 4 176 VAL 176 176 176 VAL VAL H . n 
D 4 177 LEU 177 177 177 LEU LEU H . n 
D 4 178 GLN 178 178 178 GLN GLN H . n 
D 4 179 SER 179 179 179 SER SER H . n 
D 4 180 ASP 180 180 180 ASP ASP H . n 
D 4 181 LEU 181 181 181 LEU LEU H . n 
D 4 182 TYR 182 182 182 TYR TYR H . n 
D 4 183 THR 183 183 183 THR THR H . n 
D 4 184 LEU 184 184 184 LEU LEU H . n 
D 4 185 SER 185 185 185 SER SER H . n 
D 4 186 SER 186 186 186 SER SER H . n 
D 4 187 SER 187 187 187 SER SER H . n 
D 4 188 VAL 188 188 188 VAL VAL H . n 
D 4 189 THR 189 189 189 THR THR H . n 
D 4 190 VAL 190 190 190 VAL VAL H . n 
D 4 191 PRO 191 191 191 PRO PRO H . n 
D 4 192 SER 192 192 192 SER SER H . n 
D 4 193 SER 193 193 193 SER SER H . n 
D 4 194 THR 194 194 194 THR THR H . n 
D 4 195 TRP 195 195 195 TRP TRP H . n 
D 4 196 PRO 196 196 196 PRO PRO H . n 
D 4 197 SER 197 197 197 SER SER H . n 
D 4 198 GLU 198 198 198 GLU GLU H . n 
D 4 199 THR 199 199 199 THR THR H . n 
D 4 200 VAL 200 200 200 VAL VAL H . n 
D 4 201 THR 201 201 201 THR THR H . n 
D 4 202 CYS 202 202 202 CYS CYS H . n 
D 4 203 ASN 203 203 203 ASN ASN H . n 
D 4 204 VAL 204 204 204 VAL VAL H . n 
D 4 205 ALA 205 205 205 ALA ALA H . n 
D 4 206 HIS 206 206 206 HIS HIS H . n 
D 4 207 PRO 207 207 207 PRO PRO H . n 
D 4 208 ALA 208 208 208 ALA ALA H . n 
D 4 209 SER 209 209 209 SER SER H . n 
D 4 210 SER 210 210 210 SER SER H . n 
D 4 211 THR 211 211 211 THR THR H . n 
D 4 212 LYS 212 212 212 LYS LYS H . n 
D 4 213 VAL 213 213 213 VAL VAL H . n 
D 4 214 ASP 214 214 214 ASP ASP H . n 
D 4 215 LYS 215 215 215 LYS LYS H . n 
D 4 216 LYS 216 216 216 LYS LYS H . n 
D 4 217 ILE 217 217 217 ILE ILE H . n 
D 4 218 VAL 218 218 218 VAL VAL H . n 
D 4 219 PRO 219 219 219 PRO PRO H . n 
D 4 220 ARG 220 220 220 ARG ARG H . n 
D 4 221 ASP 221 221 ?   ?   ?   H . n 
D 4 222 CYS 222 222 ?   ?   ?   H . n 
D 4 223 GLY 223 223 ?   ?   ?   H . n 
D 4 224 CYS 224 224 ?   ?   ?   H . n 
D 4 225 LYS 225 225 ?   ?   ?   H . n 
D 4 226 PRO 226 226 ?   ?   ?   H . n 
D 4 227 CYS 227 227 ?   ?   ?   H . n 
D 4 228 ILE 228 228 ?   ?   ?   H . n 
D 4 229 CYS 229 229 ?   ?   ?   H . n 
D 4 230 THR 230 230 ?   ?   ?   H . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        VRW 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   VRW 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 5 NAG 1 701 631 NAG NAG A . 
F 5 NAG 1 702 632 NAG NAG A . 
G 5 NAG 1 703 634 NAG NAG A . 
H 5 NAG 1 704 635 NAG NAG A . 
I 6 VRW 1 601 601 VRW JPH B . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8KDD 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8KDD 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8KDD 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               213.868 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.943 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  'HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8KDD 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.83 
_refine.ls_d_res_low                             3.83 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     84047 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    100.00 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.28500 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.28500 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'PARAMETERS FOR MASK CACLULATION' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD WITH PHASES' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.519 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             14.155 
_refine.overall_SU_ML                            0.198 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'ELECTRON MICROSCOPY' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       . 
_refine_hist.d_res_low                        . 
_refine_hist.number_atoms_solvent             ? 
_refine_hist.number_atoms_total               10626 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        ? 
_refine_hist.pdbx_number_atoms_nucleic_acid   ? 
_refine_hist.pdbx_number_atoms_ligand         ? 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.011  0.012  10903 ? r_bond_refined_d             ? ? 
'ELECTRON MICROSCOPY' ? 0.000  0.016  10310 ? r_bond_other_d               ? ? 
'ELECTRON MICROSCOPY' ? 1.981  1.643  14870 ? r_angle_refined_deg          ? ? 
'ELECTRON MICROSCOPY' ? 0.698  1.567  23764 ? r_angle_other_deg            ? ? 
'ELECTRON MICROSCOPY' ? 8.364  5.000  1356  ? r_dihedral_angle_1_deg       ? ? 
'ELECTRON MICROSCOPY' ? 13.535 5.222  45    ? r_dihedral_angle_2_deg       ? ? 
'ELECTRON MICROSCOPY' ? 14.663 10.000 1751  ? r_dihedral_angle_3_deg       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_dihedral_angle_4_deg       ? ? 
'ELECTRON MICROSCOPY' ? 0.080  0.200  1712  ? r_chiral_restr               ? ? 
'ELECTRON MICROSCOPY' ? 0.004  0.020  12655 ? r_gen_planes_refined         ? ? 
'ELECTRON MICROSCOPY' ? 0.001  0.020  2477  ? r_gen_planes_other           ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'ELECTRON MICROSCOPY' ? 32.809 19.108 5439  ? r_mcbond_it                  ? ? 
'ELECTRON MICROSCOPY' ? 32.794 19.108 5439  ? r_mcbond_other               ? ? 
'ELECTRON MICROSCOPY' ? 46.340 34.484 6790  ? r_mcangle_it                 ? ? 
'ELECTRON MICROSCOPY' ? 46.336 34.489 6791  ? r_mcangle_other              ? ? 
'ELECTRON MICROSCOPY' ? 41.444 22.764 5464  ? r_scbond_it                  ? ? 
'ELECTRON MICROSCOPY' ? 41.440 22.765 5465  ? r_scbond_other               ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'ELECTRON MICROSCOPY' ? 63.281 40.092 8081  ? r_scangle_other              ? ? 
'ELECTRON MICROSCOPY' ? 68.393 233.56 43070 ? r_long_range_B_refined       ? ? 
'ELECTRON MICROSCOPY' ? 68.392 233.56 43071 ? r_long_range_B_other         ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'ELECTRON MICROSCOPY' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'ELECTRON MICROSCOPY' 
_refine_ls_shell.d_res_high                       3.600 
_refine_ls_shell.d_res_low                        3.694 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             0 
_refine_ls_shell.number_reflns_R_work             6153 
_refine_ls_shell.percent_reflns_obs               100.00 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  1.454 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.000 
# 
_struct.entry_id                     8KDD 
_struct.title                        'Structure of LAT1-CD98hc-Fab170 in complex with JPH203, consensus map' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8KDD 
_struct_keywords.text            'Transporter, Amino acid, Complex, Cancer, TRANSPORT PROTEIN' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 5 ? 
G N N 5 ? 
H N N 5 ? 
I N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP 4F2_HUMAN  P08195 ? 1 
;ELQPPEASIAVVSIPRQLPGSHSEAGVQGLSAGDDSELGSHCVAQTGLELLASGDPLPSASQNAEMIETGSDCVTQAGLQ
LLASSDPPALASKNAEVTGTMSQDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEKNGLVKIKVAEDEAEAAAAAKF
TGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAGNL
AGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWFST
QVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQILSLLESNKDLLLT
SSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAALPG
QPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQNE
RFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPYAA
;
2 
2 UNP LAT1_HUMAN Q01650 ? 2 
;MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAG
SPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPL
FPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV
GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHL
GVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFF
SFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN
KPKWLLQGIFSTTVLCQKLMQVVPQET
;
1 
3 PDB 8KDD       8KDD   ? 3 ? 1 
4 PDB 8KDD       8KDD   ? 4 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8KDD A 3 ? 631 ? P08195 2 ? 630 ? 2 630 
2 2 8KDD B 1 ? 507 ? Q01650 1 ? 507 ? 1 507 
3 3 8KDD L 1 ? 220 ? 8KDD   1 ? 220 ? 1 220 
4 4 8KDD H 1 ? 230 ? 8KDD   1 ? 230 ? 1 230 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8KDD GLY A 1   ? UNP P08195 ? ? 'expression tag' 0   1  
1 8KDD SER A 2   ? UNP P08195 ? ? 'expression tag' 1   2  
2 8KDD ASP B 508 ? UNP Q01650 ? ? 'expression tag' 508 3  
2 8KDD TYR B 509 ? UNP Q01650 ? ? 'expression tag' 509 4  
2 8KDD LYS B 510 ? UNP Q01650 ? ? 'expression tag' 510 5  
2 8KDD ASP B 511 ? UNP Q01650 ? ? 'expression tag' 511 6  
2 8KDD ASP B 512 ? UNP Q01650 ? ? 'expression tag' 512 7  
2 8KDD ASP B 513 ? UNP Q01650 ? ? 'expression tag' 513 8  
2 8KDD ASP B 514 ? UNP Q01650 ? ? 'expression tag' 514 9  
2 8KDD LYS B 515 ? UNP Q01650 ? ? 'expression tag' 515 10 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 166 ? GLY A 175 ? SER A 165 GLY A 174 1 ? 10 
HELX_P HELX_P2  AA2 SER A 176 ? ARG A 207 ? SER A 175 ARG A 206 1 ? 32 
HELX_P HELX_P3  AA3 LYS A 218 ? GLY A 223 ? LYS A 217 GLY A 222 5 ? 6  
HELX_P HELX_P4  AA4 ASN A 241 ? LYS A 256 ? ASN A 240 LYS A 255 1 ? 16 
HELX_P HELX_P5  AA5 ASP A 282 ? GLY A 286 ? ASP A 281 GLY A 285 5 ? 5  
HELX_P HELX_P6  AA6 SER A 287 ? LYS A 301 ? SER A 286 LYS A 300 1 ? 15 
HELX_P HELX_P7  AA7 GLN A 323 ? GLY A 342 ? GLN A 322 GLY A 341 1 ? 20 
HELX_P HELX_P8  AA8 ASP A 350 ? LEU A 354 ? ASP A 349 LEU A 353 5 ? 5  
HELX_P HELX_P9  AA9 ASP A 356 ? SER A 372 ? ASP A 355 SER A 371 1 ? 17 
HELX_P HELX_P10 AB1 ASP A 385 ? ASN A 396 ? ASP A 384 ASN A 395 1 ? 12 
HELX_P HELX_P11 AB2 HIS A 415 ? GLY A 428 ? HIS A 414 GLY A 427 1 ? 14 
HELX_P HELX_P12 AB3 LEU A 441 ? PHE A 445 ? LEU A 440 PHE A 444 5 ? 5  
HELX_P HELX_P13 AB4 LEU A 450 ? PHE A 459 ? LEU A 449 PHE A 458 1 ? 10 
HELX_P HELX_P14 AB5 GLY A 470 ? GLY A 474 ? GLY A 469 GLY A 473 5 ? 5  
HELX_P HELX_P15 AB6 SER A 505 ? MET A 508 ? SER A 504 MET A 507 5 ? 4  
HELX_P HELX_P16 AB7 THR A 509 ? GLU A 515 ? THR A 508 GLU A 514 1 ? 7  
HELX_P HELX_P17 AB8 SER A 519 ? GLU A 534 ? SER A 518 GLU A 533 1 ? 16 
HELX_P HELX_P18 AB9 GLU A 534 ? GLY A 540 ? GLU A 533 GLY A 539 1 ? 7  
HELX_P HELX_P19 AC1 PRO A 585 ? SER A 589 ? PRO A 584 SER A 588 5 ? 5  
HELX_P HELX_P20 AC2 GLU A 613 ? LEU A 615 ? GLU A 612 LEU A 614 5 ? 3  
HELX_P HELX_P21 AC3 THR B 51  ? GLY B 65  ? THR B 51  GLY B 65  1 ? 15 
HELX_P HELX_P22 AC4 SER B 66  ? VAL B 70  ? SER B 66  VAL B 70  5 ? 5  
HELX_P HELX_P23 AC5 THR B 71  ? GLY B 80  ? THR B 71  GLY B 80  1 ? 10 
HELX_P HELX_P24 AC6 SER B 81  ? ILE B 110 ? SER B 81  ILE B 110 1 ? 30 
HELX_P HELX_P25 AC7 TYR B 117 ? GLY B 125 ? TYR B 117 GLY B 125 1 ? 9  
HELX_P HELX_P26 AC8 GLY B 125 ? ILE B 139 ? GLY B 125 ILE B 139 1 ? 15 
HELX_P HELX_P27 AC9 ILE B 139 ? LYS B 158 ? ILE B 139 LYS B 158 1 ? 20 
HELX_P HELX_P28 AD1 PRO B 159 ? PHE B 161 ? PRO B 159 PHE B 161 5 ? 3  
HELX_P HELX_P29 AD2 PRO B 167 ? SER B 189 ? PRO B 167 SER B 189 1 ? 23 
HELX_P HELX_P30 AD3 SER B 189 ? LYS B 221 ? SER B 189 LYS B 221 1 ? 33 
HELX_P HELX_P31 AD4 ASP B 239 ? PHE B 252 ? ASP B 239 PHE B 252 1 ? 14 
HELX_P HELX_P32 AD5 ALA B 253 ? GLY B 255 ? ALA B 253 GLY B 255 5 ? 3  
HELX_P HELX_P33 AD6 ASN B 258 ? MET B 267 ? ASN B 258 MET B 267 5 ? 10 
HELX_P HELX_P34 AD7 ASN B 269 ? ILE B 280 ? ASN B 269 ILE B 280 1 ? 12 
HELX_P HELX_P35 AD8 SER B 281 ? THR B 298 ? SER B 281 THR B 298 1 ? 18 
HELX_P HELX_P36 AD9 SER B 301 ? LEU B 306 ? SER B 301 LEU B 306 1 ? 6  
HELX_P HELX_P37 AE1 ALA B 310 ? GLY B 321 ? ALA B 310 GLY B 321 1 ? 12 
HELX_P HELX_P38 AE2 VAL B 322 ? SER B 324 ? VAL B 322 SER B 324 5 ? 3  
HELX_P HELX_P39 AE3 TRP B 325 ? GLU B 356 ? TRP B 325 GLU B 356 1 ? 32 
HELX_P HELX_P40 AE4 PRO B 360 ? MET B 365 ? PRO B 360 MET B 365 5 ? 6  
HELX_P HELX_P41 AE5 PRO B 373 ? LEU B 386 ? PRO B 373 LEU B 386 1 ? 14 
HELX_P HELX_P42 AE6 ILE B 393 ? PHE B 399 ? ILE B 393 PHE B 399 1 ? 7  
HELX_P HELX_P43 AE7 PHE B 400 ? LYS B 422 ? PHE B 400 LYS B 422 1 ? 23 
HELX_P HELX_P44 AE8 LEU B 433 ? THR B 454 ? LEU B 433 THR B 454 1 ? 22 
HELX_P HELX_P45 AE9 VAL B 456 ? LEU B 466 ? VAL B 456 LEU B 466 1 ? 11 
HELX_P HELX_P46 AF1 SER B 467 ? VAL B 476 ? SER B 467 VAL B 476 1 ? 10 
HELX_P HELX_P47 AF2 PRO B 482 ? GLN B 501 ? PRO B 482 GLN B 501 1 ? 20 
HELX_P HELX_P48 AF3 GLN C 85  ? LEU C 89  ? GLN L 85  LEU L 89  5 ? 5  
HELX_P HELX_P49 AF4 GLU C 129 ? SER C 133 ? GLU L 129 SER L 133 5 ? 5  
HELX_P HELX_P50 AF5 LYS C 189 ? ARG C 194 ? LYS L 189 ARG L 194 1 ? 6  
HELX_P HELX_P51 AF6 THR D 28  ? TYR D 32  ? THR H 28  TYR H 32  5 ? 5  
HELX_P HELX_P52 AF7 GLN D 62  ? LYS D 65  ? GLN H 62  LYS H 65  5 ? 4  
HELX_P HELX_P53 AF8 THR D 87  ? SER D 91  ? THR H 87  SER H 91  5 ? 5  
HELX_P HELX_P54 AF9 ALA D 136 ? ASN D 140 ? ALA H 136 ASN H 140 5 ? 5  
HELX_P HELX_P55 AG1 THR D 194 ? GLU D 198 ? THR H 194 GLU H 198 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?   ? A CYS 211 SG  ? ? ? 1_555 B CYS 164 SG ? ? A CYS 210 B CYS 164 1_555 ? ? ? ? ? ? ? 2.167 ? ?               
disulf2 disulf ?   ? C CYS 23  SG  ? ? ? 1_555 C CYS 94  SG ? ? L CYS 23  L CYS 94  1_555 ? ? ? ? ? ? ? 2.098 ? ?               
disulf3 disulf ?   ? C CYS 140 SG  ? ? ? 1_555 C CYS 200 SG ? ? L CYS 140 L CYS 200 1_555 ? ? ? ? ? ? ? 2.039 ? ?               
disulf4 disulf ?   ? D CYS 22  SG  ? ? ? 1_555 D CYS 96  SG ? ? H CYS 22  H CYS 96  1_555 ? ? ? ? ? ? ? 2.075 ? ?               
disulf5 disulf ?   ? D CYS 147 SG  ? ? ? 1_555 D CYS 202 SG ? ? H CYS 147 H CYS 202 1_555 ? ? ? ? ? ? ? 2.078 ? ?               
covale1 covale one ? A ASN 366 ND2 ? ? ? 1_555 G NAG .   C1 ? ? A ASN 365 A NAG 703 1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale2 covale one ? A ASN 382 ND2 ? ? ? 1_555 E NAG .   C1 ? ? A ASN 381 A NAG 701 1_555 ? ? ? ? ? ? ? 1.438 ? N-Glycosylation 
covale3 covale one ? A ASN 425 ND2 ? ? ? 1_555 H NAG .   C1 ? ? A ASN 424 A NAG 704 1_555 ? ? ? ? ? ? ? 1.442 ? N-Glycosylation 
covale4 covale one ? A ASN 507 ND2 ? ? ? 1_555 F NAG .   C1 ? ? A ASN 506 A NAG 702 1_555 ? ? ? ? ? ? ? 1.466 ? N-Glycosylation 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 NAG E .   ? ASN A 382 ? NAG A 701 ? 1_555 ASN A 381 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2 NAG F .   ? ASN A 507 ? NAG A 702 ? 1_555 ASN A 506 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3 NAG G .   ? ASN A 366 ? NAG A 703 ? 1_555 ASN A 365 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4 NAG H .   ? ASN A 425 ? NAG A 704 ? 1_555 ASN A 424 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5 CYS A 211 ? CYS B 164 ? CYS A 210 ? 1_555 CYS B 164 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
6 CYS C 23  ? CYS C 94  ? CYS L 23  ? 1_555 CYS L 94  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
7 CYS C 140 ? CYS C 200 ? CYS L 140 ? 1_555 CYS L 200 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
8 CYS D 22  ? CYS D 96  ? CYS H 22  ? 1_555 CYS H 96  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
9 CYS D 147 ? CYS D 202 ? CYS H 147 ? 1_555 CYS H 202 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 SER 7   C . ? SER 7   L PRO 8   C ? PRO 8   L 1 -8.65 
2 ILE 100 C . ? ILE 100 L PRO 101 C ? PRO 101 L 1 6.42  
3 TYR 146 C . ? TYR 146 L PRO 147 C ? PRO 147 L 1 -4.56 
4 PHE 153 D . ? PHE 153 H PRO 154 D ? PRO 154 H 1 -8.72 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 6 ? 
AA3 ? 2 ? 
AA4 ? 4 ? 
AA5 ? 6 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 6 ? 
AB1 ? 4 ? 
AB2 ? 4 ? 
AB3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA1 6 7 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? parallel      
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AA9 5 6 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LEU A 400 ? THR A 402 ? LEU A 399 THR A 401 
AA1 2 LEU A 376 ? GLY A 380 ? LEU A 375 GLY A 379 
AA1 3 GLY A 345 ? VAL A 348 ? GLY A 344 VAL A 347 
AA1 4 ILE A 306 ? ASP A 308 ? ILE A 305 ASP A 307 
AA1 5 VAL A 261 ? LEU A 262 ? VAL A 260 LEU A 261 
AA1 6 LEU A 225 ? ILE A 228 ? LEU A 224 ILE A 227 
AA1 7 VAL A 466 ? SER A 468 ? VAL A 465 SER A 467 
AA2 1 ASP A 541 ? PHE A 545 ? ASP A 540 PHE A 544 
AA2 2 PHE A 552 ? HIS A 557 ? PHE A 551 HIS A 556 
AA2 3 ARG A 563 ? LEU A 568 ? ARG A 562 LEU A 567 
AA2 4 LEU A 623 ? PHE A 627 ? LEU A 622 PHE A 626 
AA2 5 LYS A 593 ? SER A 599 ? LYS A 592 SER A 598 
AA2 6 PRO A 609 ? GLU A 611 ? PRO A 608 GLU A 610 
AA3 1 GLY A 574 ? LEU A 575 ? GLY A 573 LEU A 574 
AA3 2 THR C 99  ? ILE C 100 ? THR L 99  ILE L 100 
AA4 1 LEU C 4   ? SER C 7   ? LEU L 4   SER L 7   
AA4 2 VAL C 19  ? SER C 25  ? VAL L 19  SER L 25  
AA4 3 ASP C 76  ? ILE C 81  ? ASP L 76  ILE L 81  
AA4 4 PHE C 68  ? SER C 73  ? PHE L 68  SER L 73  
AA5 1 SER C 10  ? SER C 14  ? SER L 10  SER L 14  
AA5 2 THR C 108 ? LYS C 113 ? THR L 108 LYS L 113 
AA5 3 LEU C 91  ? GLN C 95  ? LEU L 91  GLN L 95  
AA5 4 ALA C 40  ? GLN C 44  ? ALA L 40  GLN L 44  
AA5 5 LYS C 51  ? TYR C 55  ? LYS L 51  TYR L 55  
AA5 6 THR C 59  ? ARG C 60  ? THR L 59  ARG L 60  
AA6 1 THR C 120 ? PHE C 124 ? THR L 120 PHE L 124 
AA6 2 GLY C 135 ? PHE C 145 ? GLY L 135 PHE L 145 
AA6 3 TYR C 179 ? THR C 188 ? TYR L 179 THR L 188 
AA6 4 VAL C 165 ? TRP C 169 ? VAL L 165 TRP L 169 
AA7 1 SER C 159 ? ARG C 161 ? SER L 159 ARG L 161 
AA7 2 ILE C 150 ? ILE C 156 ? ILE L 150 ILE L 156 
AA7 3 SER C 197 ? HIS C 204 ? SER L 197 HIS L 204 
AA7 4 ILE C 211 ? ASN C 216 ? ILE L 211 ASN L 216 
AA8 1 GLN D 3   ? GLN D 6   ? GLN H 3   GLN H 6   
AA8 2 VAL D 18  ? SER D 25  ? VAL H 18  SER H 25  
AA8 3 THR D 78  ? LEU D 83  ? THR H 78  LEU H 83  
AA8 4 ALA D 68  ? ASP D 73  ? ALA H 68  ASP H 73  
AA9 1 ALA D 9   ? VAL D 12  ? ALA H 9   VAL H 12  
AA9 2 THR D 114 ? VAL D 118 ? THR H 114 VAL H 118 
AA9 3 ALA D 92  ? ARG D 98  ? ALA H 92  ARG H 98  
AA9 4 MET D 34  ? LEU D 39  ? MET H 34  LEU H 39  
AA9 5 LEU D 45  ? ILE D 51  ? LEU H 45  ILE H 51  
AA9 6 SER D 58  ? TYR D 60  ? SER H 58  TYR H 60  
AB1 1 ALA D 9   ? VAL D 12  ? ALA H 9   VAL H 12  
AB1 2 THR D 114 ? VAL D 118 ? THR H 114 VAL H 118 
AB1 3 ALA D 92  ? ARG D 98  ? ALA H 92  ARG H 98  
AB1 4 TYR D 109 ? TRP D 110 ? TYR H 109 TRP H 110 
AB2 1 SER D 127 ? LEU D 131 ? SER H 127 LEU H 131 
AB2 2 MET D 142 ? TYR D 152 ? MET H 142 TYR H 152 
AB2 3 LEU D 181 ? PRO D 191 ? LEU H 181 PRO H 191 
AB2 4 VAL D 170 ? GLN D 178 ? VAL H 170 GLN H 178 
AB3 1 THR D 201 ? ALA D 205 ? THR H 201 ALA H 205 
AB3 2 LYS D 212 ? LYS D 216 ? LYS H 212 LYS H 216 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O THR A 402 ? O THR A 401 N ALA A 379 ? N ALA A 378 
AA1 2 3 O ILE A 378 ? O ILE A 377 N PHE A 346 ? N PHE A 345 
AA1 3 4 O GLY A 345 ? O GLY A 344 N LEU A 307 ? N LEU A 306 
AA1 4 5 O ILE A 306 ? O ILE A 305 N LEU A 262 ? N LEU A 261 
AA1 5 6 O VAL A 261 ? O VAL A 260 N ILE A 228 ? N ILE A 227 
AA1 6 7 N ARG A 227 ? N ARG A 226 O PHE A 467 ? O PHE A 466 
AA2 1 2 N ASP A 541 ? N ASP A 540 O HIS A 557 ? O HIS A 556 
AA2 2 3 N ARG A 556 ? N ARG A 555 O PHE A 564 ? O PHE A 563 
AA2 3 4 N ARG A 563 ? N ARG A 562 O PHE A 627 ? O PHE A 626 
AA2 4 5 O ARG A 626 ? O ARG A 625 N ASP A 595 ? N ASP A 594 
AA2 5 6 N ALA A 594 ? N ALA A 593 O LEU A 610 ? O LEU A 609 
AA3 1 2 N GLY A 574 ? N GLY A 573 O ILE C 100 ? O ILE L 100 
AA4 1 2 N THR C 5   ? N THR L 5   O LYS C 24  ? O LYS L 24  
AA4 2 3 N MET C 21  ? N MET L 21  O LEU C 79  ? O LEU L 79  
AA4 3 4 O THR C 78  ? O THR L 78  N SER C 71  ? N SER L 71  
AA5 1 2 N MET C 13  ? N MET L 13  O GLU C 111 ? O GLU L 111 
AA5 2 3 O THR C 108 ? O THR L 108 N TYR C 92  ? N TYR L 92  
AA5 3 4 O LEU C 91  ? O LEU L 91  N GLN C 44  ? N GLN L 44  
AA5 4 5 N TRP C 41  ? N TRP L 41  O LEU C 53  ? O LEU L 53  
AA5 5 6 N TYR C 55  ? N TYR L 55  O THR C 59  ? O THR L 59  
AA6 1 2 N THR C 120 ? N THR L 120 O ASN C 143 ? O ASN L 143 
AA6 2 3 N LEU C 142 ? N LEU L 142 O MET C 181 ? O MET L 181 
AA6 3 4 O THR C 184 ? O THR L 184 N LEU C 166 ? N LEU L 166 
AA7 1 2 O ARG C 161 ? O ARG L 161 N TRP C 154 ? N TRP L 154 
AA7 2 3 N LYS C 153 ? N LYS L 153 O GLU C 201 ? O GLU L 201 
AA7 3 4 N TYR C 198 ? N TYR L 198 O PHE C 215 ? O PHE L 215 
AA8 1 2 N GLN D 5   ? N GLN H 5   O LYS D 23  ? O LYS H 23  
AA8 2 3 N LEU D 20  ? N LEU H 20  O LEU D 81  ? O LEU H 81  
AA8 3 4 O GLN D 82  ? O GLN H 82  N THR D 69  ? N THR H 69  
AA9 1 2 N GLU D 10  ? N GLU H 10  O THR D 117 ? O THR H 117 
AA9 2 3 O THR D 114 ? O THR H 114 N TYR D 94  ? N TYR H 94  
AA9 3 4 O TYR D 95  ? O TYR H 95  N VAL D 37  ? N VAL H 37  
AA9 4 5 N ARG D 38  ? N ARG H 38  O GLU D 46  ? O GLU H 46  
AA9 5 6 N GLU D 50  ? N GLU H 50  O TYR D 59  ? O TYR H 59  
AB1 1 2 N GLU D 10  ? N GLU H 10  O THR D 117 ? O THR H 117 
AB1 2 3 O THR D 114 ? O THR H 114 N TYR D 94  ? N TYR H 94  
AB1 3 4 N ARG D 98  ? N ARG H 98  O TYR D 109 ? O TYR H 109 
AB2 1 2 N TYR D 129 ? N TYR H 129 O LEU D 148 ? O LEU H 148 
AB2 2 3 N TYR D 152 ? N TYR H 152 O TYR D 182 ? O TYR H 182 
AB2 3 4 O LEU D 181 ? O LEU H 181 N GLN D 178 ? N GLN H 178 
AB3 1 2 N VAL D 204 ? N VAL H 204 O VAL D 213 ? O VAL H 213 
# 
_pdbx_entry_details.entry_id                   8KDD 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1 1 CA A SER 552 ? ? CB A SER 552 ? ? 1.433 1.525 -0.092 0.015 N 
2 1 CB H HIS 35  ? ? CG H HIS 35  ? ? 1.396 1.492 -0.096 0.016 N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 CA A TRP 193 ? ? CB  A TRP 193 ? ? CG  A TRP 193 ? ? 125.44 113.70 11.74 1.90 N 
2  1 CA A CYS 210 ? ? CB  A CYS 210 ? ? SG  A CYS 210 ? ? 121.86 114.20 7.66  1.10 N 
3  1 NE A ARG 348 ? ? CZ  A ARG 348 ? ? NH1 A ARG 348 ? ? 116.33 120.30 -3.97 0.50 N 
4  1 NE A ARG 348 ? ? CZ  A ARG 348 ? ? NH2 A ARG 348 ? ? 123.38 120.30 3.08  0.50 N 
5  1 NE A ARG 451 ? ? CZ  A ARG 451 ? ? NH1 A ARG 451 ? ? 116.06 120.30 -4.24 0.50 N 
6  1 NE A ARG 555 ? ? CZ  A ARG 555 ? ? NH2 A ARG 555 ? ? 124.09 120.30 3.79  0.50 N 
7  1 CB A GLN 579 ? ? CA  A GLN 579 ? ? C   A GLN 579 ? ? 123.06 110.40 12.66 2.00 N 
8  1 NE A ARG 603 ? ? CZ  A ARG 603 ? ? NH1 A ARG 603 ? ? 116.35 120.30 -3.95 0.50 N 
9  1 NE A ARG 625 ? ? CZ  A ARG 625 ? ? NH2 A ARG 625 ? ? 123.55 120.30 3.25  0.50 N 
10 1 CB H TYR 59  ? ? CG  H TYR 59  ? ? CD2 H TYR 59  ? ? 125.99 121.00 4.99  0.60 N 
11 1 CA H TYR 103 ? ? CB  H TYR 103 ? ? CG  H TYR 103 ? ? 126.51 113.40 13.11 1.90 N 
12 1 CG H TYR 103 ? ? CD2 H TYR 103 ? ? CE2 H TYR 103 ? ? 127.01 121.30 5.71  0.80 N 
13 1 CZ H TYR 103 ? ? CE2 H TYR 103 ? ? CD2 H TYR 103 ? ? 113.74 119.80 -6.06 0.90 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 TYR A 225 ? ? -172.34 114.55  
2  1 LYS A 257 ? ? -78.41  38.58   
3  1 ASP A 270 ? ? 58.64   9.87    
4  1 ASN A 311 ? ? -92.97  50.06   
5  1 PHE A 319 ? ? 60.72   166.34  
6  1 ASP A 373 ? ? -95.76  40.09   
7  1 SER A 410 ? ? 55.07   15.99   
8  1 ARG A 429 ? ? -69.32  -171.32 
9  1 ALA A 438 ? ? -148.34 -49.21  
10 1 PHE A 444 ? ? -129.01 -51.64  
11 1 ALA A 486 ? ? -159.83 67.96   
12 1 HIS A 538 ? ? -161.92 20.26   
13 1 PRO A 548 ? ? -56.07  -72.64  
14 1 ALA A 576 ? ? -153.06 21.39   
15 1 GLN A 579 ? ? -150.18 84.10   
16 1 VAL B 70  ? ? -141.37 -16.17  
17 1 VAL B 123 ? ? -125.22 -68.08  
18 1 ILE B 139 ? ? -127.15 -63.92  
19 1 SER B 189 ? ? -173.48 133.83  
20 1 ASN B 269 ? ? -153.25 76.65   
21 1 SER B 307 ? ? -140.92 17.95   
22 1 ALA B 310 ? ? -160.52 67.17   
23 1 ILE B 393 ? ? -139.55 -45.75  
24 1 THR B 454 ? ? -158.12 79.80   
25 1 VAL B 476 ? ? -126.04 -51.25  
26 1 SER L 26  ? ? -69.98  0.97    
27 1 LEU L 53  ? ? -101.32 -63.28  
28 1 PHE L 56  ? ? 39.99   48.03   
29 1 THR L 57  ? ? 65.12   -30.04  
30 1 SER L 83  ? ? -160.54 90.42   
31 1 ASN L 144 ? ? 61.65   69.24   
32 1 ASP H 55  ? ? -155.98 9.21    
33 1 THR H 69  ? ? -163.81 110.70  
34 1 ALA H 92  ? ? -173.63 -178.58 
35 1 TYR H 103 ? ? 92.42   -21.91  
36 1 PRO H 154 ? ? -77.70  -169.24 
# 
loop_
_pdbx_validate_peptide_omega.id 
_pdbx_validate_peptide_omega.PDB_model_num 
_pdbx_validate_peptide_omega.auth_comp_id_1 
_pdbx_validate_peptide_omega.auth_asym_id_1 
_pdbx_validate_peptide_omega.auth_seq_id_1 
_pdbx_validate_peptide_omega.PDB_ins_code_1 
_pdbx_validate_peptide_omega.label_alt_id_1 
_pdbx_validate_peptide_omega.auth_comp_id_2 
_pdbx_validate_peptide_omega.auth_asym_id_2 
_pdbx_validate_peptide_omega.auth_seq_id_2 
_pdbx_validate_peptide_omega.PDB_ins_code_2 
_pdbx_validate_peptide_omega.label_alt_id_2 
_pdbx_validate_peptide_omega.omega 
1 1 SER A 410 ? ? THR A 411 ? ? 139.61  
2 1 TRP A 557 ? ? ASP A 558 ? ? -149.52 
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 525 ? ? 0.106 'SIDE CHAIN' 
2 1 ARG A 562 ? ? 0.102 'SIDE CHAIN' 
3 1 ARG H 100 ? ? 0.142 'SIDE CHAIN' 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8KDD 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8KDD 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.83 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               137883 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
loop_
_em_entity_assembly.id 
_em_entity_assembly.parent_id 
_em_entity_assembly.source 
_em_entity_assembly.type 
_em_entity_assembly.name 
_em_entity_assembly.details 
_em_entity_assembly.synonym 
_em_entity_assembly.oligomeric_details 
_em_entity_assembly.entity_id_list 
1 0 'MULTIPLE SOURCES' COMPLEX LAT1-CD98hc-Fab170 ? ? ? 1,2,4,3 
2 1 RECOMBINANT        COMPLEX LAT1-CD98hc        ? ? ? 1,2     
3 1 'MULTIPLE SOURCES' COMPLEX Fab170             ? ? ? 4,3     
# 
_em_imaging.entry_id                        8KDD 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8KDD 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8KDD 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A GLY 0   ? A GLY 1   
2   1 Y 1 A SER 1   ? A SER 2   
3   1 Y 1 A GLU 2   ? A GLU 3   
4   1 Y 1 A LEU 3   ? A LEU 4   
5   1 Y 1 A GLN 4   ? A GLN 5   
6   1 Y 1 A PRO 5   ? A PRO 6   
7   1 Y 1 A PRO 6   ? A PRO 7   
8   1 Y 1 A GLU 7   ? A GLU 8   
9   1 Y 1 A ALA 8   ? A ALA 9   
10  1 Y 1 A SER 9   ? A SER 10  
11  1 Y 1 A ILE 10  ? A ILE 11  
12  1 Y 1 A ALA 11  ? A ALA 12  
13  1 Y 1 A VAL 12  ? A VAL 13  
14  1 Y 1 A VAL 13  ? A VAL 14  
15  1 Y 1 A SER 14  ? A SER 15  
16  1 Y 1 A ILE 15  ? A ILE 16  
17  1 Y 1 A PRO 16  ? A PRO 17  
18  1 Y 1 A ARG 17  ? A ARG 18  
19  1 Y 1 A GLN 18  ? A GLN 19  
20  1 Y 1 A LEU 19  ? A LEU 20  
21  1 Y 1 A PRO 20  ? A PRO 21  
22  1 Y 1 A GLY 21  ? A GLY 22  
23  1 Y 1 A SER 22  ? A SER 23  
24  1 Y 1 A HIS 23  ? A HIS 24  
25  1 Y 1 A SER 24  ? A SER 25  
26  1 Y 1 A GLU 25  ? A GLU 26  
27  1 Y 1 A ALA 26  ? A ALA 27  
28  1 Y 1 A GLY 27  ? A GLY 28  
29  1 Y 1 A VAL 28  ? A VAL 29  
30  1 Y 1 A GLN 29  ? A GLN 30  
31  1 Y 1 A GLY 30  ? A GLY 31  
32  1 Y 1 A LEU 31  ? A LEU 32  
33  1 Y 1 A SER 32  ? A SER 33  
34  1 Y 1 A ALA 33  ? A ALA 34  
35  1 Y 1 A GLY 34  ? A GLY 35  
36  1 Y 1 A ASP 35  ? A ASP 36  
37  1 Y 1 A ASP 36  ? A ASP 37  
38  1 Y 1 A SER 37  ? A SER 38  
39  1 Y 1 A GLU 38  ? A GLU 39  
40  1 Y 1 A LEU 39  ? A LEU 40  
41  1 Y 1 A GLY 40  ? A GLY 41  
42  1 Y 1 A SER 41  ? A SER 42  
43  1 Y 1 A HIS 42  ? A HIS 43  
44  1 Y 1 A CYS 43  ? A CYS 44  
45  1 Y 1 A VAL 44  ? A VAL 45  
46  1 Y 1 A ALA 45  ? A ALA 46  
47  1 Y 1 A GLN 46  ? A GLN 47  
48  1 Y 1 A THR 47  ? A THR 48  
49  1 Y 1 A GLY 48  ? A GLY 49  
50  1 Y 1 A LEU 49  ? A LEU 50  
51  1 Y 1 A GLU 50  ? A GLU 51  
52  1 Y 1 A LEU 51  ? A LEU 52  
53  1 Y 1 A LEU 52  ? A LEU 53  
54  1 Y 1 A ALA 53  ? A ALA 54  
55  1 Y 1 A SER 54  ? A SER 55  
56  1 Y 1 A GLY 55  ? A GLY 56  
57  1 Y 1 A ASP 56  ? A ASP 57  
58  1 Y 1 A PRO 57  ? A PRO 58  
59  1 Y 1 A LEU 58  ? A LEU 59  
60  1 Y 1 A PRO 59  ? A PRO 60  
61  1 Y 1 A SER 60  ? A SER 61  
62  1 Y 1 A ALA 61  ? A ALA 62  
63  1 Y 1 A SER 62  ? A SER 63  
64  1 Y 1 A GLN 63  ? A GLN 64  
65  1 Y 1 A ASN 64  ? A ASN 65  
66  1 Y 1 A ALA 65  ? A ALA 66  
67  1 Y 1 A GLU 66  ? A GLU 67  
68  1 Y 1 A MET 67  ? A MET 68  
69  1 Y 1 A ILE 68  ? A ILE 69  
70  1 Y 1 A GLU 69  ? A GLU 70  
71  1 Y 1 A THR 70  ? A THR 71  
72  1 Y 1 A GLY 71  ? A GLY 72  
73  1 Y 1 A SER 72  ? A SER 73  
74  1 Y 1 A ASP 73  ? A ASP 74  
75  1 Y 1 A CYS 74  ? A CYS 75  
76  1 Y 1 A VAL 75  ? A VAL 76  
77  1 Y 1 A THR 76  ? A THR 77  
78  1 Y 1 A GLN 77  ? A GLN 78  
79  1 Y 1 A ALA 78  ? A ALA 79  
80  1 Y 1 A GLY 79  ? A GLY 80  
81  1 Y 1 A LEU 80  ? A LEU 81  
82  1 Y 1 A GLN 81  ? A GLN 82  
83  1 Y 1 A LEU 82  ? A LEU 83  
84  1 Y 1 A LEU 83  ? A LEU 84  
85  1 Y 1 A ALA 84  ? A ALA 85  
86  1 Y 1 A SER 85  ? A SER 86  
87  1 Y 1 A SER 86  ? A SER 87  
88  1 Y 1 A ASP 87  ? A ASP 88  
89  1 Y 1 A PRO 88  ? A PRO 89  
90  1 Y 1 A PRO 89  ? A PRO 90  
91  1 Y 1 A ALA 90  ? A ALA 91  
92  1 Y 1 A LEU 91  ? A LEU 92  
93  1 Y 1 A ALA 92  ? A ALA 93  
94  1 Y 1 A SER 93  ? A SER 94  
95  1 Y 1 A LYS 94  ? A LYS 95  
96  1 Y 1 A ASN 95  ? A ASN 96  
97  1 Y 1 A ALA 96  ? A ALA 97  
98  1 Y 1 A GLU 97  ? A GLU 98  
99  1 Y 1 A VAL 98  ? A VAL 99  
100 1 Y 1 A THR 99  ? A THR 100 
101 1 Y 1 A GLY 100 ? A GLY 101 
102 1 Y 1 A THR 101 ? A THR 102 
103 1 Y 1 A MET 102 ? A MET 103 
104 1 Y 1 A SER 103 ? A SER 104 
105 1 Y 1 A GLN 104 ? A GLN 105 
106 1 Y 1 A ASP 105 ? A ASP 106 
107 1 Y 1 A THR 106 ? A THR 107 
108 1 Y 1 A GLU 107 ? A GLU 108 
109 1 Y 1 A VAL 108 ? A VAL 109 
110 1 Y 1 A ASP 109 ? A ASP 110 
111 1 Y 1 A MET 110 ? A MET 111 
112 1 Y 1 A LYS 111 ? A LYS 112 
113 1 Y 1 A GLU 112 ? A GLU 113 
114 1 Y 1 A VAL 113 ? A VAL 114 
115 1 Y 1 A GLU 114 ? A GLU 115 
116 1 Y 1 A LEU 115 ? A LEU 116 
117 1 Y 1 A ASN 116 ? A ASN 117 
118 1 Y 1 A GLU 117 ? A GLU 118 
119 1 Y 1 A LEU 118 ? A LEU 119 
120 1 Y 1 A GLU 119 ? A GLU 120 
121 1 Y 1 A PRO 120 ? A PRO 121 
122 1 Y 1 A GLU 121 ? A GLU 122 
123 1 Y 1 A LYS 122 ? A LYS 123 
124 1 Y 1 A GLN 123 ? A GLN 124 
125 1 Y 1 A PRO 124 ? A PRO 125 
126 1 Y 1 A MET 125 ? A MET 126 
127 1 Y 1 A ASN 126 ? A ASN 127 
128 1 Y 1 A ALA 127 ? A ALA 128 
129 1 Y 1 A ALA 128 ? A ALA 129 
130 1 Y 1 A SER 129 ? A SER 130 
131 1 Y 1 A GLY 130 ? A GLY 131 
132 1 Y 1 A ALA 131 ? A ALA 132 
133 1 Y 1 A ALA 132 ? A ALA 133 
134 1 Y 1 A MET 133 ? A MET 134 
135 1 Y 1 A SER 134 ? A SER 135 
136 1 Y 1 A LEU 135 ? A LEU 136 
137 1 Y 1 A ALA 136 ? A ALA 137 
138 1 Y 1 A GLY 137 ? A GLY 138 
139 1 Y 1 A ALA 138 ? A ALA 139 
140 1 Y 1 A GLU 139 ? A GLU 140 
141 1 Y 1 A LYS 140 ? A LYS 141 
142 1 Y 1 A ASN 141 ? A ASN 142 
143 1 Y 1 A GLY 142 ? A GLY 143 
144 1 Y 1 A LEU 143 ? A LEU 144 
145 1 Y 1 A VAL 144 ? A VAL 145 
146 1 Y 1 A LYS 145 ? A LYS 146 
147 1 Y 1 A ILE 146 ? A ILE 147 
148 1 Y 1 A LYS 147 ? A LYS 148 
149 1 Y 1 A VAL 148 ? A VAL 149 
150 1 Y 1 A ALA 149 ? A ALA 150 
151 1 Y 1 A GLU 150 ? A GLU 151 
152 1 Y 1 A ASP 151 ? A ASP 152 
153 1 Y 1 A GLU 152 ? A GLU 153 
154 1 Y 1 A ALA 153 ? A ALA 154 
155 1 Y 1 A GLU 154 ? A GLU 155 
156 1 Y 1 A ALA 155 ? A ALA 156 
157 1 Y 1 A ALA 156 ? A ALA 157 
158 1 Y 1 A ALA 157 ? A ALA 158 
159 1 Y 1 A ALA 158 ? A ALA 159 
160 1 Y 1 A ALA 159 ? A ALA 160 
161 1 Y 1 A LYS 160 ? A LYS 161 
162 1 Y 1 A PHE 161 ? A PHE 162 
163 1 Y 1 B MET 1   ? B MET 1   
164 1 Y 1 B ALA 2   ? B ALA 2   
165 1 Y 1 B GLY 3   ? B GLY 3   
166 1 Y 1 B ALA 4   ? B ALA 4   
167 1 Y 1 B GLY 5   ? B GLY 5   
168 1 Y 1 B PRO 6   ? B PRO 6   
169 1 Y 1 B LYS 7   ? B LYS 7   
170 1 Y 1 B ARG 8   ? B ARG 8   
171 1 Y 1 B ARG 9   ? B ARG 9   
172 1 Y 1 B ALA 10  ? B ALA 10  
173 1 Y 1 B LEU 11  ? B LEU 11  
174 1 Y 1 B ALA 12  ? B ALA 12  
175 1 Y 1 B ALA 13  ? B ALA 13  
176 1 Y 1 B PRO 14  ? B PRO 14  
177 1 Y 1 B ALA 15  ? B ALA 15  
178 1 Y 1 B ALA 16  ? B ALA 16  
179 1 Y 1 B GLU 17  ? B GLU 17  
180 1 Y 1 B GLU 18  ? B GLU 18  
181 1 Y 1 B LYS 19  ? B LYS 19  
182 1 Y 1 B GLU 20  ? B GLU 20  
183 1 Y 1 B GLU 21  ? B GLU 21  
184 1 Y 1 B ALA 22  ? B ALA 22  
185 1 Y 1 B ARG 23  ? B ARG 23  
186 1 Y 1 B GLU 24  ? B GLU 24  
187 1 Y 1 B LYS 25  ? B LYS 25  
188 1 Y 1 B MET 26  ? B MET 26  
189 1 Y 1 B LEU 27  ? B LEU 27  
190 1 Y 1 B ALA 28  ? B ALA 28  
191 1 Y 1 B ALA 29  ? B ALA 29  
192 1 Y 1 B LYS 30  ? B LYS 30  
193 1 Y 1 B SER 31  ? B SER 31  
194 1 Y 1 B ALA 32  ? B ALA 32  
195 1 Y 1 B ASP 33  ? B ASP 33  
196 1 Y 1 B GLY 34  ? B GLY 34  
197 1 Y 1 B SER 35  ? B SER 35  
198 1 Y 1 B ALA 36  ? B ALA 36  
199 1 Y 1 B PRO 37  ? B PRO 37  
200 1 Y 1 B ALA 38  ? B ALA 38  
201 1 Y 1 B GLY 39  ? B GLY 39  
202 1 Y 1 B GLU 40  ? B GLU 40  
203 1 Y 1 B GLY 41  ? B GLY 41  
204 1 Y 1 B GLU 42  ? B GLU 42  
205 1 Y 1 B ASP 223 ? B ASP 223 
206 1 Y 1 B VAL 224 ? B VAL 224 
207 1 Y 1 B SER 225 ? B SER 225 
208 1 Y 1 B ASN 226 ? B ASN 226 
209 1 Y 1 B LEU 227 ? B LEU 227 
210 1 Y 1 B ASP 228 ? B ASP 228 
211 1 Y 1 B PRO 229 ? B PRO 229 
212 1 Y 1 B ASN 230 ? B ASN 230 
213 1 Y 1 B PHE 231 ? B PHE 231 
214 1 Y 1 B SER 232 ? B SER 232 
215 1 Y 1 B ASP 508 ? B ASP 508 
216 1 Y 1 B TYR 509 ? B TYR 509 
217 1 Y 1 B LYS 510 ? B LYS 510 
218 1 Y 1 B ASP 511 ? B ASP 511 
219 1 Y 1 B ASP 512 ? B ASP 512 
220 1 Y 1 B ASP 513 ? B ASP 513 
221 1 Y 1 B ASP 514 ? B ASP 514 
222 1 Y 1 B LYS 515 ? B LYS 515 
223 1 Y 1 L ASN 218 ? C ASN 218 
224 1 Y 1 L GLU 219 ? C GLU 219 
225 1 Y 1 L CYS 220 ? C CYS 220 
226 1 Y 1 H ASP 221 ? D ASP 221 
227 1 Y 1 H CYS 222 ? D CYS 222 
228 1 Y 1 H GLY 223 ? D GLY 223 
229 1 Y 1 H CYS 224 ? D CYS 224 
230 1 Y 1 H LYS 225 ? D LYS 225 
231 1 Y 1 H PRO 226 ? D PRO 226 
232 1 Y 1 H CYS 227 ? D CYS 227 
233 1 Y 1 H ILE 228 ? D ILE 228 
234 1 Y 1 H CYS 229 ? D CYS 229 
235 1 Y 1 H THR 230 ? D THR 230 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HIS N    N  N N 137 
HIS CA   C  N S 138 
HIS C    C  N N 139 
HIS O    O  N N 140 
HIS CB   C  N N 141 
HIS CG   C  Y N 142 
HIS ND1  N  Y N 143 
HIS CD2  C  Y N 144 
HIS CE1  C  Y N 145 
HIS NE2  N  Y N 146 
HIS OXT  O  N N 147 
HIS H    H  N N 148 
HIS H2   H  N N 149 
HIS HA   H  N N 150 
HIS HB2  H  N N 151 
HIS HB3  H  N N 152 
HIS HD1  H  N N 153 
HIS HD2  H  N N 154 
HIS HE1  H  N N 155 
HIS HE2  H  N N 156 
HIS HXT  H  N N 157 
ILE N    N  N N 158 
ILE CA   C  N S 159 
ILE C    C  N N 160 
ILE O    O  N N 161 
ILE CB   C  N S 162 
ILE CG1  C  N N 163 
ILE CG2  C  N N 164 
ILE CD1  C  N N 165 
ILE OXT  O  N N 166 
ILE H    H  N N 167 
ILE H2   H  N N 168 
ILE HA   H  N N 169 
ILE HB   H  N N 170 
ILE HG12 H  N N 171 
ILE HG13 H  N N 172 
ILE HG21 H  N N 173 
ILE HG22 H  N N 174 
ILE HG23 H  N N 175 
ILE HD11 H  N N 176 
ILE HD12 H  N N 177 
ILE HD13 H  N N 178 
ILE HXT  H  N N 179 
LEU N    N  N N 180 
LEU CA   C  N S 181 
LEU C    C  N N 182 
LEU O    O  N N 183 
LEU CB   C  N N 184 
LEU CG   C  N N 185 
LEU CD1  C  N N 186 
LEU CD2  C  N N 187 
LEU OXT  O  N N 188 
LEU H    H  N N 189 
LEU H2   H  N N 190 
LEU HA   H  N N 191 
LEU HB2  H  N N 192 
LEU HB3  H  N N 193 
LEU HG   H  N N 194 
LEU HD11 H  N N 195 
LEU HD12 H  N N 196 
LEU HD13 H  N N 197 
LEU HD21 H  N N 198 
LEU HD22 H  N N 199 
LEU HD23 H  N N 200 
LEU HXT  H  N N 201 
LYS N    N  N N 202 
LYS CA   C  N S 203 
LYS C    C  N N 204 
LYS O    O  N N 205 
LYS CB   C  N N 206 
LYS CG   C  N N 207 
LYS CD   C  N N 208 
LYS CE   C  N N 209 
LYS NZ   N  N N 210 
LYS OXT  O  N N 211 
LYS H    H  N N 212 
LYS H2   H  N N 213 
LYS HA   H  N N 214 
LYS HB2  H  N N 215 
LYS HB3  H  N N 216 
LYS HG2  H  N N 217 
LYS HG3  H  N N 218 
LYS HD2  H  N N 219 
LYS HD3  H  N N 220 
LYS HE2  H  N N 221 
LYS HE3  H  N N 222 
LYS HZ1  H  N N 223 
LYS HZ2  H  N N 224 
LYS HZ3  H  N N 225 
LYS HXT  H  N N 226 
MET N    N  N N 227 
MET CA   C  N S 228 
MET C    C  N N 229 
MET O    O  N N 230 
MET CB   C  N N 231 
MET CG   C  N N 232 
MET SD   S  N N 233 
MET CE   C  N N 234 
MET OXT  O  N N 235 
MET H    H  N N 236 
MET H2   H  N N 237 
MET HA   H  N N 238 
MET HB2  H  N N 239 
MET HB3  H  N N 240 
MET HG2  H  N N 241 
MET HG3  H  N N 242 
MET HE1  H  N N 243 
MET HE2  H  N N 244 
MET HE3  H  N N 245 
MET HXT  H  N N 246 
NAG C1   C  N R 247 
NAG C2   C  N R 248 
NAG C3   C  N R 249 
NAG C4   C  N S 250 
NAG C5   C  N R 251 
NAG C6   C  N N 252 
NAG C7   C  N N 253 
NAG C8   C  N N 254 
NAG N2   N  N N 255 
NAG O1   O  N N 256 
NAG O3   O  N N 257 
NAG O4   O  N N 258 
NAG O5   O  N N 259 
NAG O6   O  N N 260 
NAG O7   O  N N 261 
NAG H1   H  N N 262 
NAG H2   H  N N 263 
NAG H3   H  N N 264 
NAG H4   H  N N 265 
NAG H5   H  N N 266 
NAG H61  H  N N 267 
NAG H62  H  N N 268 
NAG H81  H  N N 269 
NAG H82  H  N N 270 
NAG H83  H  N N 271 
NAG HN2  H  N N 272 
NAG HO1  H  N N 273 
NAG HO3  H  N N 274 
NAG HO4  H  N N 275 
NAG HO6  H  N N 276 
PHE N    N  N N 277 
PHE CA   C  N S 278 
PHE C    C  N N 279 
PHE O    O  N N 280 
PHE CB   C  N N 281 
PHE CG   C  Y N 282 
PHE CD1  C  Y N 283 
PHE CD2  C  Y N 284 
PHE CE1  C  Y N 285 
PHE CE2  C  Y N 286 
PHE CZ   C  Y N 287 
PHE OXT  O  N N 288 
PHE H    H  N N 289 
PHE H2   H  N N 290 
PHE HA   H  N N 291 
PHE HB2  H  N N 292 
PHE HB3  H  N N 293 
PHE HD1  H  N N 294 
PHE HD2  H  N N 295 
PHE HE1  H  N N 296 
PHE HE2  H  N N 297 
PHE HZ   H  N N 298 
PHE HXT  H  N N 299 
PRO N    N  N N 300 
PRO CA   C  N S 301 
PRO C    C  N N 302 
PRO O    O  N N 303 
PRO CB   C  N N 304 
PRO CG   C  N N 305 
PRO CD   C  N N 306 
PRO OXT  O  N N 307 
PRO H    H  N N 308 
PRO HA   H  N N 309 
PRO HB2  H  N N 310 
PRO HB3  H  N N 311 
PRO HG2  H  N N 312 
PRO HG3  H  N N 313 
PRO HD2  H  N N 314 
PRO HD3  H  N N 315 
PRO HXT  H  N N 316 
SER N    N  N N 317 
SER CA   C  N S 318 
SER C    C  N N 319 
SER O    O  N N 320 
SER CB   C  N N 321 
SER OG   O  N N 322 
SER OXT  O  N N 323 
SER H    H  N N 324 
SER H2   H  N N 325 
SER HA   H  N N 326 
SER HB2  H  N N 327 
SER HB3  H  N N 328 
SER HG   H  N N 329 
SER HXT  H  N N 330 
THR N    N  N N 331 
THR CA   C  N S 332 
THR C    C  N N 333 
THR O    O  N N 334 
THR CB   C  N R 335 
THR OG1  O  N N 336 
THR CG2  C  N N 337 
THR OXT  O  N N 338 
THR H    H  N N 339 
THR H2   H  N N 340 
THR HA   H  N N 341 
THR HB   H  N N 342 
THR HG1  H  N N 343 
THR HG21 H  N N 344 
THR HG22 H  N N 345 
THR HG23 H  N N 346 
THR HXT  H  N N 347 
TRP N    N  N N 348 
TRP CA   C  N S 349 
TRP C    C  N N 350 
TRP O    O  N N 351 
TRP CB   C  N N 352 
TRP CG   C  Y N 353 
TRP CD1  C  Y N 354 
TRP CD2  C  Y N 355 
TRP NE1  N  Y N 356 
TRP CE2  C  Y N 357 
TRP CE3  C  Y N 358 
TRP CZ2  C  Y N 359 
TRP CZ3  C  Y N 360 
TRP CH2  C  Y N 361 
TRP OXT  O  N N 362 
TRP H    H  N N 363 
TRP H2   H  N N 364 
TRP HA   H  N N 365 
TRP HB2  H  N N 366 
TRP HB3  H  N N 367 
TRP HD1  H  N N 368 
TRP HE1  H  N N 369 
TRP HE3  H  N N 370 
TRP HZ2  H  N N 371 
TRP HZ3  H  N N 372 
TRP HH2  H  N N 373 
TRP HXT  H  N N 374 
TYR N    N  N N 375 
TYR CA   C  N S 376 
TYR C    C  N N 377 
TYR O    O  N N 378 
TYR CB   C  N N 379 
TYR CG   C  Y N 380 
TYR CD1  C  Y N 381 
TYR CD2  C  Y N 382 
TYR CE1  C  Y N 383 
TYR CE2  C  Y N 384 
TYR CZ   C  Y N 385 
TYR OH   O  N N 386 
TYR OXT  O  N N 387 
TYR H    H  N N 388 
TYR H2   H  N N 389 
TYR HA   H  N N 390 
TYR HB2  H  N N 391 
TYR HB3  H  N N 392 
TYR HD1  H  N N 393 
TYR HD2  H  N N 394 
TYR HE1  H  N N 395 
TYR HE2  H  N N 396 
TYR HH   H  N N 397 
TYR HXT  H  N N 398 
VAL N    N  N N 399 
VAL CA   C  N S 400 
VAL C    C  N N 401 
VAL O    O  N N 402 
VAL CB   C  N N 403 
VAL CG1  C  N N 404 
VAL CG2  C  N N 405 
VAL OXT  O  N N 406 
VAL H    H  N N 407 
VAL H2   H  N N 408 
VAL HA   H  N N 409 
VAL HB   H  N N 410 
VAL HG11 H  N N 411 
VAL HG12 H  N N 412 
VAL HG13 H  N N 413 
VAL HG21 H  N N 414 
VAL HG22 H  N N 415 
VAL HG23 H  N N 416 
VAL HXT  H  N N 417 
VRW N1   N  Y N 418 
VRW N3   N  N N 419 
VRW C4   C  Y N 420 
VRW C5   C  Y N 421 
VRW C6   C  Y N 422 
VRW C2   C  Y N 423 
VRW C1   C  Y N 424 
VRW C3   C  Y N 425 
VRW C7   C  Y N 426 
VRW C8   C  Y N 427 
VRW C9   C  Y N 428 
VRW C10  C  Y N 429 
VRW C11  C  Y N 430 
VRW C12  C  Y N 431 
VRW C13  C  Y N 432 
VRW O1   O  Y N 433 
VRW C14  C  N N 434 
VRW O2   O  N N 435 
VRW C15  C  Y N 436 
VRW C16  C  Y N 437 
VRW C17  C  Y N 438 
VRW C18  C  Y N 439 
VRW C19  C  Y N 440 
VRW C20  C  Y N 441 
VRW CL1  CL N N 442 
VRW C21  C  N N 443 
VRW C22  C  N S 444 
VRW C23  C  N N 445 
VRW O3   O  N N 446 
VRW O4   O  N N 447 
VRW N2   N  N N 448 
VRW CL2  CL N N 449 
VRW H1   H  N N 450 
VRW H2   H  N N 451 
VRW H3   H  N N 452 
VRW H4   H  N N 453 
VRW H5   H  N N 454 
VRW H6   H  N N 455 
VRW H7   H  N N 456 
VRW H8   H  N N 457 
VRW H9   H  N N 458 
VRW H10  H  N N 459 
VRW H11  H  N N 460 
VRW H12  H  N N 461 
VRW H13  H  N N 462 
VRW H14  H  N N 463 
VRW H15  H  N N 464 
VRW H16  H  N N 465 
VRW H17  H  N N 466 
VRW H18  H  N N 467 
VRW H19  H  N N 468 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
NAG C1  C2   sing N N 235 
NAG C1  O1   sing N N 236 
NAG C1  O5   sing N N 237 
NAG C1  H1   sing N N 238 
NAG C2  C3   sing N N 239 
NAG C2  N2   sing N N 240 
NAG C2  H2   sing N N 241 
NAG C3  C4   sing N N 242 
NAG C3  O3   sing N N 243 
NAG C3  H3   sing N N 244 
NAG C4  C5   sing N N 245 
NAG C4  O4   sing N N 246 
NAG C4  H4   sing N N 247 
NAG C5  C6   sing N N 248 
NAG C5  O5   sing N N 249 
NAG C5  H5   sing N N 250 
NAG C6  O6   sing N N 251 
NAG C6  H61  sing N N 252 
NAG C6  H62  sing N N 253 
NAG C7  C8   sing N N 254 
NAG C7  N2   sing N N 255 
NAG C7  O7   doub N N 256 
NAG C8  H81  sing N N 257 
NAG C8  H82  sing N N 258 
NAG C8  H83  sing N N 259 
NAG N2  HN2  sing N N 260 
NAG O1  HO1  sing N N 261 
NAG O3  HO3  sing N N 262 
NAG O4  HO4  sing N N 263 
NAG O6  HO6  sing N N 264 
PHE N   CA   sing N N 265 
PHE N   H    sing N N 266 
PHE N   H2   sing N N 267 
PHE CA  C    sing N N 268 
PHE CA  CB   sing N N 269 
PHE CA  HA   sing N N 270 
PHE C   O    doub N N 271 
PHE C   OXT  sing N N 272 
PHE CB  CG   sing N N 273 
PHE CB  HB2  sing N N 274 
PHE CB  HB3  sing N N 275 
PHE CG  CD1  doub Y N 276 
PHE CG  CD2  sing Y N 277 
PHE CD1 CE1  sing Y N 278 
PHE CD1 HD1  sing N N 279 
PHE CD2 CE2  doub Y N 280 
PHE CD2 HD2  sing N N 281 
PHE CE1 CZ   doub Y N 282 
PHE CE1 HE1  sing N N 283 
PHE CE2 CZ   sing Y N 284 
PHE CE2 HE2  sing N N 285 
PHE CZ  HZ   sing N N 286 
PHE OXT HXT  sing N N 287 
PRO N   CA   sing N N 288 
PRO N   CD   sing N N 289 
PRO N   H    sing N N 290 
PRO CA  C    sing N N 291 
PRO CA  CB   sing N N 292 
PRO CA  HA   sing N N 293 
PRO C   O    doub N N 294 
PRO C   OXT  sing N N 295 
PRO CB  CG   sing N N 296 
PRO CB  HB2  sing N N 297 
PRO CB  HB3  sing N N 298 
PRO CG  CD   sing N N 299 
PRO CG  HG2  sing N N 300 
PRO CG  HG3  sing N N 301 
PRO CD  HD2  sing N N 302 
PRO CD  HD3  sing N N 303 
PRO OXT HXT  sing N N 304 
SER N   CA   sing N N 305 
SER N   H    sing N N 306 
SER N   H2   sing N N 307 
SER CA  C    sing N N 308 
SER CA  CB   sing N N 309 
SER CA  HA   sing N N 310 
SER C   O    doub N N 311 
SER C   OXT  sing N N 312 
SER CB  OG   sing N N 313 
SER CB  HB2  sing N N 314 
SER CB  HB3  sing N N 315 
SER OG  HG   sing N N 316 
SER OXT HXT  sing N N 317 
THR N   CA   sing N N 318 
THR N   H    sing N N 319 
THR N   H2   sing N N 320 
THR CA  C    sing N N 321 
THR CA  CB   sing N N 322 
THR CA  HA   sing N N 323 
THR C   O    doub N N 324 
THR C   OXT  sing N N 325 
THR CB  OG1  sing N N 326 
THR CB  CG2  sing N N 327 
THR CB  HB   sing N N 328 
THR OG1 HG1  sing N N 329 
THR CG2 HG21 sing N N 330 
THR CG2 HG22 sing N N 331 
THR CG2 HG23 sing N N 332 
THR OXT HXT  sing N N 333 
TRP N   CA   sing N N 334 
TRP N   H    sing N N 335 
TRP N   H2   sing N N 336 
TRP CA  C    sing N N 337 
TRP CA  CB   sing N N 338 
TRP CA  HA   sing N N 339 
TRP C   O    doub N N 340 
TRP C   OXT  sing N N 341 
TRP CB  CG   sing N N 342 
TRP CB  HB2  sing N N 343 
TRP CB  HB3  sing N N 344 
TRP CG  CD1  doub Y N 345 
TRP CG  CD2  sing Y N 346 
TRP CD1 NE1  sing Y N 347 
TRP CD1 HD1  sing N N 348 
TRP CD2 CE2  doub Y N 349 
TRP CD2 CE3  sing Y N 350 
TRP NE1 CE2  sing Y N 351 
TRP NE1 HE1  sing N N 352 
TRP CE2 CZ2  sing Y N 353 
TRP CE3 CZ3  doub Y N 354 
TRP CE3 HE3  sing N N 355 
TRP CZ2 CH2  doub Y N 356 
TRP CZ2 HZ2  sing N N 357 
TRP CZ3 CH2  sing Y N 358 
TRP CZ3 HZ3  sing N N 359 
TRP CH2 HH2  sing N N 360 
TRP OXT HXT  sing N N 361 
TYR N   CA   sing N N 362 
TYR N   H    sing N N 363 
TYR N   H2   sing N N 364 
TYR CA  C    sing N N 365 
TYR CA  CB   sing N N 366 
TYR CA  HA   sing N N 367 
TYR C   O    doub N N 368 
TYR C   OXT  sing N N 369 
TYR CB  CG   sing N N 370 
TYR CB  HB2  sing N N 371 
TYR CB  HB3  sing N N 372 
TYR CG  CD1  doub Y N 373 
TYR CG  CD2  sing Y N 374 
TYR CD1 CE1  sing Y N 375 
TYR CD1 HD1  sing N N 376 
TYR CD2 CE2  doub Y N 377 
TYR CD2 HD2  sing N N 378 
TYR CE1 CZ   doub Y N 379 
TYR CE1 HE1  sing N N 380 
TYR CE2 CZ   sing Y N 381 
TYR CE2 HE2  sing N N 382 
TYR CZ  OH   sing N N 383 
TYR OH  HH   sing N N 384 
TYR OXT HXT  sing N N 385 
VAL N   CA   sing N N 386 
VAL N   H    sing N N 387 
VAL N   H2   sing N N 388 
VAL CA  C    sing N N 389 
VAL CA  CB   sing N N 390 
VAL CA  HA   sing N N 391 
VAL C   O    doub N N 392 
VAL C   OXT  sing N N 393 
VAL CB  CG1  sing N N 394 
VAL CB  CG2  sing N N 395 
VAL CB  HB   sing N N 396 
VAL CG1 HG11 sing N N 397 
VAL CG1 HG12 sing N N 398 
VAL CG1 HG13 sing N N 399 
VAL CG2 HG21 sing N N 400 
VAL CG2 HG22 sing N N 401 
VAL CG2 HG23 sing N N 402 
VAL OXT HXT  sing N N 403 
VRW CL2 C16  sing N N 404 
VRW C14 O2   sing N N 405 
VRW C14 C12  sing N N 406 
VRW O2  C15  sing N N 407 
VRW C11 C12  doub Y N 408 
VRW C11 C10  sing Y N 409 
VRW C16 C15  doub Y N 410 
VRW C16 C17  sing Y N 411 
VRW C12 C13  sing Y N 412 
VRW C15 C20  sing Y N 413 
VRW N3  C10  sing N N 414 
VRW C10 C9   doub Y N 415 
VRW C17 C18  doub Y N 416 
VRW C20 CL1  sing N N 417 
VRW C20 C19  doub Y N 418 
VRW C13 O1   sing Y N 419 
VRW C13 C8   doub Y N 420 
VRW O1  C7   sing Y N 421 
VRW C18 C19  sing Y N 422 
VRW C18 C21  sing N N 423 
VRW C9  C8   sing Y N 424 
VRW N2  C22  sing N N 425 
VRW C8  N1   sing Y N 426 
VRW C22 C21  sing N N 427 
VRW C22 C23  sing N N 428 
VRW C7  N1   doub Y N 429 
VRW C7  C4   sing N N 430 
VRW C5  C4   doub Y N 431 
VRW C5  C6   sing Y N 432 
VRW C23 O3   doub N N 433 
VRW C23 O4   sing N N 434 
VRW C4  C3   sing Y N 435 
VRW C6  C1   doub Y N 436 
VRW C3  C2   doub Y N 437 
VRW C1  C2   sing Y N 438 
VRW N3  H1   sing N N 439 
VRW N3  H2   sing N N 440 
VRW C5  H3   sing N N 441 
VRW C6  H4   sing N N 442 
VRW C2  H5   sing N N 443 
VRW C1  H6   sing N N 444 
VRW C3  H7   sing N N 445 
VRW C9  H8   sing N N 446 
VRW C11 H9   sing N N 447 
VRW C14 H10  sing N N 448 
VRW C14 H11  sing N N 449 
VRW C17 H12  sing N N 450 
VRW C19 H13  sing N N 451 
VRW C21 H14  sing N N 452 
VRW C21 H15  sing N N 453 
VRW C22 H16  sing N N 454 
VRW O4  H17  sing N N 455 
VRW N2  H18  sing N N 456 
VRW N2  H19  sing N N 457 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-08-09 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8KDD 
_em_admin.last_update        2025-02-26 
_em_admin.map_release_date   2025-02-12 
_em_admin.title              'Structure of LAT1-CD98hc-Fab170 in complex with JPH203, consensus map' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.173 
# 
loop_
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
_em_entity_assembly_naturalsource.details 
? ? 2 2 9606  'Homo sapiens' ? ? ? ? ? 
? ? 3 3 10090 'Mus musculus' ? ? ? ? ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   2 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         51 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Max Planck Society' 
_pdbx_audit_support.country                Germany 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8KDD 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CL 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N   . THR A 1 163 ? 103.740 119.888 60.091  1.00 416.41 ? 162 THR A N   1 
ATOM   2     C  CA  . THR A 1 163 ? 104.653 118.734 60.354  1.00 404.88 ? 162 THR A CA  1 
ATOM   3     C  C   . THR A 1 163 ? 106.084 119.291 60.513  1.00 367.47 ? 162 THR A C   1 
ATOM   4     O  O   . THR A 1 163 ? 106.251 120.310 61.194  1.00 215.97 ? 162 THR A O   1 
ATOM   5     C  CB  . THR A 1 163 ? 104.407 117.624 59.304  1.00 367.17 ? 162 THR A CB  1 
ATOM   6     O  OG1 . THR A 1 163 ? 104.790 118.068 58.003  1.00 295.10 ? 162 THR A OG1 1 
ATOM   7     C  CG2 . THR A 1 163 ? 102.966 117.162 59.227  1.00 343.26 ? 162 THR A CG2 1 
ATOM   8     N  N   . GLY A 1 164 ? 107.097 118.630 59.903  1.00 354.74 ? 163 GLY A N   1 
ATOM   9     C  CA  . GLY A 1 164 ? 108.496 119.053 59.911  1.00 301.09 ? 163 GLY A CA  1 
ATOM   10    C  C   . GLY A 1 164 ? 109.219 118.674 58.611  1.00 292.17 ? 163 GLY A C   1 
ATOM   11    O  O   . GLY A 1 164 ? 108.597 118.630 57.551  1.00 291.19 ? 163 GLY A O   1 
ATOM   12    N  N   . LEU A 1 165 ? 110.534 118.400 58.706  1.00 312.13 ? 164 LEU A N   1 
ATOM   13    C  CA  . LEU A 1 165 ? 111.396 118.031 57.575  1.00 328.31 ? 164 LEU A CA  1 
ATOM   14    C  C   . LEU A 1 165 ? 110.946 116.725 56.905  1.00 311.85 ? 164 LEU A C   1 
ATOM   15    O  O   . LEU A 1 165 ? 110.470 115.811 57.569  1.00 350.90 ? 164 LEU A O   1 
ATOM   16    C  CB  . LEU A 1 165 ? 112.853 117.886 58.060  1.00 296.23 ? 164 LEU A CB  1 
ATOM   17    C  CG  . LEU A 1 165 ? 113.810 119.054 57.812  1.00 301.59 ? 164 LEU A CG  1 
ATOM   18    C  CD1 . LEU A 1 165 ? 113.201 120.407 58.159  1.00 329.95 ? 164 LEU A CD1 1 
ATOM   19    C  CD2 . LEU A 1 165 ? 115.080 118.850 58.617  1.00 258.75 ? 164 LEU A CD2 1 
ATOM   20    N  N   . SER A 1 166 ? 111.116 116.642 55.573  1.00 288.85 ? 165 SER A N   1 
ATOM   21    C  CA  . SER A 1 166 ? 110.921 115.414 54.813  1.00 294.68 ? 165 SER A CA  1 
ATOM   22    C  C   . SER A 1 166 ? 112.100 114.460 55.034  1.00 257.47 ? 165 SER A C   1 
ATOM   23    O  O   . SER A 1 166 ? 113.149 114.894 55.511  1.00 272.02 ? 165 SER A O   1 
ATOM   24    C  CB  . SER A 1 166 ? 110.743 115.729 53.345  1.00 376.33 ? 165 SER A CB  1 
ATOM   25    O  OG  . SER A 1 166 ? 109.678 116.647 53.146  1.00 419.33 ? 165 SER A OG  1 
ATOM   26    N  N   . LYS A 1 167 ? 111.903 113.171 54.672  1.00 245.93 ? 166 LYS A N   1 
ATOM   27    C  CA  . LYS A 1 167 ? 112.904 112.104 54.759  1.00 243.68 ? 166 LYS A CA  1 
ATOM   28    C  C   . LYS A 1 167 ? 114.243 112.556 54.182  1.00 263.70 ? 166 LYS A C   1 
ATOM   29    O  O   . LYS A 1 167 ? 115.236 112.558 54.911  1.00 212.57 ? 166 LYS A O   1 
ATOM   30    C  CB  . LYS A 1 167 ? 112.479 110.819 54.018  1.00 242.27 ? 166 LYS A CB  1 
ATOM   31    C  CG  . LYS A 1 167 ? 113.518 109.686 53.983  1.00 209.96 ? 166 LYS A CG  1 
ATOM   32    C  CD  . LYS A 1 167 ? 113.160 108.514 53.079  1.00 240.42 ? 166 LYS A CD  1 
ATOM   33    C  CE  . LYS A 1 167 ? 113.879 107.217 53.426  1.00 267.78 ? 166 LYS A CE  1 
ATOM   34    N  NZ  . LYS A 1 167 ? 115.331 107.204 53.111  1.00 235.41 ? 166 LYS A NZ  1 
ATOM   35    N  N   . GLU A 1 168 ? 114.228 112.925 52.883  1.00 305.98 ? 167 GLU A N   1 
ATOM   36    C  CA  . GLU A 1 168 ? 115.413 113.268 52.105  1.00 333.13 ? 167 GLU A CA  1 
ATOM   37    C  C   . GLU A 1 168 ? 116.089 114.493 52.716  1.00 349.83 ? 167 GLU A C   1 
ATOM   38    O  O   . GLU A 1 168 ? 117.306 114.467 52.905  1.00 354.51 ? 167 GLU A O   1 
ATOM   39    C  CB  . GLU A 1 168 ? 115.051 113.539 50.639  1.00 410.16 ? 167 GLU A CB  1 
ATOM   40    C  CG  . GLU A 1 168 ? 116.251 113.735 49.709  1.00 512.40 ? 167 GLU A CG  1 
ATOM   41    C  CD  . GLU A 1 168 ? 115.940 114.268 48.320  1.00 604.23 ? 167 GLU A CD  1 
ATOM   42    O  OE1 . GLU A 1 168 ? 114.755 114.263 47.922  1.00 643.65 ? 167 GLU A OE1 1 
ATOM   43    O  OE2 . GLU A 1 168 ? 116.891 114.693 47.635  1.00 649.02 ? 167 GLU A OE2 1 
ATOM   44    N  N   . GLU A 1 169 ? 115.283 115.535 53.015  1.00 327.31 ? 168 GLU A N   1 
ATOM   45    C  CA  . GLU A 1 169 ? 115.741 116.789 53.609  1.00 301.12 ? 168 GLU A CA  1 
ATOM   46    C  C   . GLU A 1 169 ? 116.453 116.521 54.942  1.00 313.79 ? 168 GLU A C   1 
ATOM   47    O  O   . GLU A 1 169 ? 117.556 117.012 55.152  1.00 293.45 ? 168 GLU A O   1 
ATOM   48    C  CB  . GLU A 1 169 ? 114.568 117.767 53.778  1.00 251.54 ? 168 GLU A CB  1 
ATOM   49    C  CG  . GLU A 1 169 ? 115.005 119.203 54.026  1.00 295.44 ? 168 GLU A CG  1 
ATOM   50    C  CD  . GLU A 1 169 ? 113.894 120.226 54.203  1.00 371.51 ? 168 GLU A CD  1 
ATOM   51    O  OE1 . GLU A 1 169 ? 112.706 119.848 54.140  1.00 357.63 ? 168 GLU A OE1 1 
ATOM   52    O  OE2 . GLU A 1 169 ? 114.226 121.411 54.407  1.00 441.63 ? 168 GLU A OE2 1 
ATOM   53    N  N   . LEU A 1 170 ? 115.831 115.731 55.831  1.00 301.54 ? 169 LEU A N   1 
ATOM   54    C  CA  . LEU A 1 170 ? 116.417 115.391 57.124  1.00 286.47 ? 169 LEU A CA  1 
ATOM   55    C  C   . LEU A 1 170 ? 117.747 114.638 56.950  1.00 330.33 ? 169 LEU A C   1 
ATOM   56    O  O   . LEU A 1 170 ? 118.717 115.004 57.613  1.00 356.66 ? 169 LEU A O   1 
ATOM   57    C  CB  . LEU A 1 170 ? 115.378 114.604 57.942  1.00 307.42 ? 169 LEU A CB  1 
ATOM   58    C  CG  . LEU A 1 170 ? 115.640 114.324 59.430  1.00 398.40 ? 169 LEU A CG  1 
ATOM   59    C  CD1 . LEU A 1 170 ? 116.448 113.046 59.653  1.00 426.15 ? 169 LEU A CD1 1 
ATOM   60    C  CD2 . LEU A 1 170 ? 116.329 115.486 60.131  1.00 459.36 ? 169 LEU A CD2 1 
ATOM   61    N  N   . LEU A 1 171 ? 117.804 113.617 56.067  1.00 358.35 ? 170 LEU A N   1 
ATOM   62    C  CA  . LEU A 1 171 ? 119.015 112.836 55.795  1.00 363.97 ? 170 LEU A CA  1 
ATOM   63    C  C   . LEU A 1 171 ? 120.184 113.707 55.322  1.00 352.30 ? 170 LEU A C   1 
ATOM   64    O  O   . LEU A 1 171 ? 121.296 113.551 55.845  1.00 331.80 ? 170 LEU A O   1 
ATOM   65    C  CB  . LEU A 1 171 ? 118.732 111.761 54.731  1.00 368.65 ? 170 LEU A CB  1 
ATOM   66    C  CG  . LEU A 1 171 ? 117.928 110.542 55.174  1.00 341.77 ? 170 LEU A CG  1 
ATOM   67    C  CD1 . LEU A 1 171 ? 117.688 109.617 53.995  1.00 280.86 ? 170 LEU A CD1 1 
ATOM   68    C  CD2 . LEU A 1 171 ? 118.642 109.795 56.291  1.00 386.52 ? 170 LEU A CD2 1 
ATOM   69    N  N   . LYS A 1 172 ? 119.932 114.601 54.343  1.00 331.83 ? 171 LYS A N   1 
ATOM   70    C  CA  . LYS A 1 172 ? 120.999 115.390 53.735  1.00 337.71 ? 171 LYS A CA  1 
ATOM   71    C  C   . LYS A 1 172 ? 121.644 116.305 54.786  1.00 347.68 ? 171 LYS A C   1 
ATOM   72    O  O   . LYS A 1 172 ? 122.871 116.428 54.775  1.00 379.10 ? 171 LYS A O   1 
ATOM   73    C  CB  . LYS A 1 172 ? 120.521 116.150 52.482  1.00 391.44 ? 171 LYS A CB  1 
ATOM   74    C  CG  . LYS A 1 172 ? 119.568 117.326 52.679  1.00 432.02 ? 171 LYS A CG  1 
ATOM   75    C  CD  . LYS A 1 172 ? 119.058 117.961 51.393  1.00 461.88 ? 171 LYS A CD  1 
ATOM   76    C  CE  . LYS A 1 172 ? 118.240 117.014 50.535  1.00 484.67 ? 171 LYS A CE  1 
ATOM   77    N  NZ  . LYS A 1 172 ? 117.457 117.725 49.499  1.00 497.27 ? 171 LYS A NZ  1 
ATOM   78    N  N   . VAL A 1 173 ? 120.845 116.917 55.688  1.00 302.03 ? 172 VAL A N   1 
ATOM   79    C  CA  . VAL A 1 173 ? 121.358 117.847 56.698  1.00 285.76 ? 172 VAL A CA  1 
ATOM   80    C  C   . VAL A 1 173 ? 121.988 117.068 57.869  1.00 263.47 ? 172 VAL A C   1 
ATOM   81    O  O   . VAL A 1 173 ? 123.070 117.448 58.320  1.00 240.05 ? 172 VAL A O   1 
ATOM   82    C  CB  . VAL A 1 173 ? 120.307 118.887 57.165  1.00 252.20 ? 172 VAL A CB  1 
ATOM   83    C  CG1 . VAL A 1 173 ? 120.948 119.988 58.002  1.00 288.70 ? 172 VAL A CG1 1 
ATOM   84    C  CG2 . VAL A 1 173 ? 119.552 119.554 56.019  1.00 249.23 ? 172 VAL A CG2 1 
ATOM   85    N  N   . ALA A 1 174 ? 121.343 115.981 58.348  1.00 313.43 ? 173 ALA A N   1 
ATOM   86    C  CA  . ALA A 1 174 ? 121.878 115.104 59.397  1.00 361.35 ? 173 ALA A CA  1 
ATOM   87    C  C   . ALA A 1 174 ? 123.312 114.641 59.112  1.00 345.22 ? 173 ALA A C   1 
ATOM   88    O  O   . ALA A 1 174 ? 124.118 114.578 60.044  1.00 320.75 ? 173 ALA A O   1 
ATOM   89    C  CB  . ALA A 1 174 ? 120.982 113.899 59.586  1.00 414.35 ? 173 ALA A CB  1 
ATOM   90    N  N   . GLY A 1 175 ? 123.599 114.326 57.830  1.00 308.85 ? 174 GLY A N   1 
ATOM   91    C  CA  . GLY A 1 175 ? 124.887 113.869 57.323  1.00 269.55 ? 174 GLY A CA  1 
ATOM   92    C  C   . GLY A 1 175 ? 126.116 114.682 57.749  1.00 292.11 ? 174 GLY A C   1 
ATOM   93    O  O   . GLY A 1 175 ? 127.179 114.071 57.890  1.00 225.19 ? 174 GLY A O   1 
ATOM   94    N  N   . SER A 1 176 ? 125.968 116.022 57.936  1.00 351.41 ? 175 SER A N   1 
ATOM   95    C  CA  . SER A 1 176 ? 127.042 116.963 58.276  1.00 357.70 ? 175 SER A CA  1 
ATOM   96    C  C   . SER A 1 176 ? 127.954 116.395 59.366  1.00 374.76 ? 175 SER A C   1 
ATOM   97    O  O   . SER A 1 176 ? 127.427 116.027 60.417  1.00 424.83 ? 175 SER A O   1 
ATOM   98    C  CB  . SER A 1 176 ? 126.501 118.317 58.726  1.00 307.08 ? 175 SER A CB  1 
ATOM   99    O  OG  . SER A 1 176 ? 125.776 118.973 57.694  1.00 277.67 ? 175 SER A OG  1 
ATOM   100   N  N   . PRO A 1 177 ? 129.304 116.297 59.173  1.00 369.65 ? 176 PRO A N   1 
ATOM   101   C  CA  . PRO A 1 177 ? 130.189 115.639 60.142  1.00 354.15 ? 176 PRO A CA  1 
ATOM   102   C  C   . PRO A 1 177 ? 130.023 116.074 61.598  1.00 412.88 ? 176 PRO A C   1 
ATOM   103   O  O   . PRO A 1 177 ? 130.095 115.198 62.450  1.00 493.52 ? 176 PRO A O   1 
ATOM   104   C  CB  . PRO A 1 177 ? 131.605 115.994 59.670  1.00 337.97 ? 176 PRO A CB  1 
ATOM   105   C  CG  . PRO A 1 177 ? 131.435 116.123 58.182  1.00 401.66 ? 176 PRO A CG  1 
ATOM   106   C  CD  . PRO A 1 177 ? 130.081 116.787 58.017  1.00 406.21 ? 176 PRO A CD  1 
ATOM   107   N  N   . GLY A 1 178 ? 129.797 117.381 61.853  1.00 352.36 ? 177 GLY A N   1 
ATOM   108   C  CA  . GLY A 1 178 ? 129.467 117.925 63.170  1.00 305.75 ? 177 GLY A CA  1 
ATOM   109   C  C   . GLY A 1 178 ? 128.357 117.151 63.894  1.00 299.04 ? 177 GLY A C   1 
ATOM   110   O  O   . GLY A 1 178 ? 128.595 116.675 65.016  1.00 264.63 ? 177 GLY A O   1 
ATOM   111   N  N   . TRP A 1 179 ? 127.167 117.027 63.241  1.00 269.67 ? 178 TRP A N   1 
ATOM   112   C  CA  . TRP A 1 179 ? 126.022 116.319 63.824  1.00 190.76 ? 178 TRP A CA  1 
ATOM   113   C  C   . TRP A 1 179 ? 126.306 114.818 63.957  1.00 185.13 ? 178 TRP A C   1 
ATOM   114   O  O   . TRP A 1 179 ? 125.885 114.269 64.965  1.00 283.87 ? 178 TRP A O   1 
ATOM   115   C  CB  . TRP A 1 179 ? 124.677 116.559 63.104  1.00 156.04 ? 178 TRP A CB  1 
ATOM   116   C  CG  . TRP A 1 179 ? 124.175 117.969 63.189  1.00 199.46 ? 178 TRP A CG  1 
ATOM   117   C  CD1 . TRP A 1 179 ? 123.808 118.682 62.101  1.00 293.94 ? 178 TRP A CD1 1 
ATOM   118   C  CD2 . TRP A 1 179 ? 124.013 118.861 64.319  1.00 256.86 ? 178 TRP A CD2 1 
ATOM   119   N  NE1 . TRP A 1 179 ? 123.403 119.943 62.454  1.00 345.04 ? 178 TRP A NE1 1 
ATOM   120   C  CE2 . TRP A 1 179 ? 123.525 120.089 63.811  1.00 310.96 ? 178 TRP A CE2 1 
ATOM   121   C  CE3 . TRP A 1 179 ? 124.224 118.763 65.699  1.00 298.44 ? 178 TRP A CE3 1 
ATOM   122   C  CZ2 . TRP A 1 179 ? 123.251 121.190 64.629  1.00 290.44 ? 178 TRP A CZ2 1 
ATOM   123   C  CZ3 . TRP A 1 179 ? 123.963 119.854 66.509  1.00 295.27 ? 178 TRP A CZ3 1 
ATOM   124   C  CH2 . TRP A 1 179 ? 123.483 121.055 65.981  1.00 260.04 ? 178 TRP A CH2 1 
ATOM   125   N  N   . VAL A 1 180 ? 126.999 114.158 63.002  1.00 180.54 ? 179 VAL A N   1 
ATOM   126   C  CA  . VAL A 1 180 ? 127.370 112.738 63.110  1.00 221.70 ? 179 VAL A CA  1 
ATOM   127   C  C   . VAL A 1 180 ? 128.245 112.500 64.348  1.00 216.56 ? 179 VAL A C   1 
ATOM   128   O  O   . VAL A 1 180 ? 127.976 111.552 65.090  1.00 307.07 ? 179 VAL A O   1 
ATOM   129   C  CB  . VAL A 1 180 ? 128.067 112.183 61.847  1.00 292.70 ? 179 VAL A CB  1 
ATOM   130   C  CG1 . VAL A 1 180 ? 128.605 110.756 62.053  1.00 253.43 ? 179 VAL A CG1 1 
ATOM   131   C  CG2 . VAL A 1 180 ? 127.148 112.247 60.625  1.00 348.03 ? 179 VAL A CG2 1 
ATOM   132   N  N   . ARG A 1 181 ? 129.256 113.356 64.575  1.00 204.67 ? 180 ARG A N   1 
ATOM   133   C  CA  . ARG A 1 181 ? 130.080 113.289 65.776  1.00 259.50 ? 180 ARG A CA  1 
ATOM   134   C  C   . ARG A 1 181 ? 129.240 113.566 67.037  1.00 309.23 ? 180 ARG A C   1 
ATOM   135   O  O   . ARG A 1 181 ? 129.460 112.896 68.047  1.00 305.59 ? 180 ARG A O   1 
ATOM   136   C  CB  . ARG A 1 181 ? 131.305 114.213 65.660  1.00 288.75 ? 180 ARG A CB  1 
ATOM   137   C  CG  . ARG A 1 181 ? 132.426 113.689 64.764  1.00 320.73 ? 180 ARG A CG  1 
ATOM   138   C  CD  . ARG A 1 181 ? 132.975 112.321 65.180  1.00 397.99 ? 180 ARG A CD  1 
ATOM   139   N  NE  . ARG A 1 181 ? 134.400 112.074 64.901  1.00 436.51 ? 180 ARG A NE  1 
ATOM   140   C  CZ  . ARG A 1 181 ? 135.097 110.990 65.273  1.00 403.74 ? 180 ARG A CZ  1 
ATOM   141   N  NH1 . ARG A 1 181 ? 136.402 110.923 65.050  1.00 322.04 ? 180 ARG A NH1 1 
ATOM   142   N  NH2 . ARG A 1 181 ? 134.497 109.973 65.875  1.00 406.75 ? 180 ARG A NH2 1 
ATOM   143   N  N   . THR A 1 182 ? 128.284 114.519 66.996  1.00 292.51 ? 181 THR A N   1 
ATOM   144   C  CA  . THR A 1 182 ? 127.403 114.814 68.131  1.00 273.93 ? 181 THR A CA  1 
ATOM   145   C  C   . THR A 1 182 ? 126.570 113.583 68.515  1.00 226.24 ? 181 THR A C   1 
ATOM   146   O  O   . THR A 1 182 ? 126.484 113.270 69.699  1.00 217.11 ? 181 THR A O   1 
ATOM   147   C  CB  . THR A 1 182 ? 126.534 116.055 67.853  1.00 263.91 ? 181 THR A CB  1 
ATOM   148   O  OG1 . THR A 1 182 ? 127.440 117.117 67.544  1.00 260.02 ? 181 THR A OG1 1 
ATOM   149   C  CG2 . THR A 1 182 ? 125.630 116.482 68.990  1.00 294.70 ? 181 THR A CG2 1 
ATOM   150   N  N   . ARG A 1 183 ? 125.975 112.890 67.527  1.00 216.64 ? 182 ARG A N   1 
ATOM   151   C  CA  . ARG A 1 183 ? 125.237 111.646 67.735  1.00 232.31 ? 182 ARG A CA  1 
ATOM   152   C  C   . ARG A 1 183 ? 126.142 110.579 68.370  1.00 221.20 ? 182 ARG A C   1 
ATOM   153   O  O   . ARG A 1 183 ? 125.701 109.919 69.313  1.00 349.47 ? 182 ARG A O   1 
ATOM   154   C  CB  . ARG A 1 183 ? 124.571 111.167 66.429  1.00 239.16 ? 182 ARG A CB  1 
ATOM   155   C  CG  . ARG A 1 183 ? 123.413 112.056 65.968  1.00 232.83 ? 182 ARG A CG  1 
ATOM   156   C  CD  . ARG A 1 183 ? 122.459 111.424 64.961  1.00 234.70 ? 182 ARG A CD  1 
ATOM   157   N  NE  . ARG A 1 183 ? 123.015 111.280 63.613  1.00 286.52 ? 182 ARG A NE  1 
ATOM   158   C  CZ  . ARG A 1 183 ? 123.095 112.225 62.663  1.00 344.33 ? 182 ARG A CZ  1 
ATOM   159   N  NH1 . ARG A 1 183 ? 123.734 111.954 61.536  1.00 360.74 ? 182 ARG A NH1 1 
ATOM   160   N  NH2 . ARG A 1 183 ? 122.563 113.433 62.808  1.00 337.89 ? 182 ARG A NH2 1 
ATOM   161   N  N   . TRP A 1 184 ? 127.384 110.413 67.884  1.00 184.96 ? 183 TRP A N   1 
ATOM   162   C  CA  . TRP A 1 184 ? 128.372 109.501 68.464  1.00 178.43 ? 183 TRP A CA  1 
ATOM   163   C  C   . TRP A 1 184 ? 128.734 109.887 69.893  1.00 176.16 ? 183 TRP A C   1 
ATOM   164   O  O   . TRP A 1 184 ? 128.798 108.999 70.760  1.00 242.93 ? 183 TRP A O   1 
ATOM   165   C  CB  . TRP A 1 184 ? 129.660 109.478 67.643  1.00 256.62 ? 183 TRP A CB  1 
ATOM   166   C  CG  . TRP A 1 184 ? 130.769 108.681 68.274  1.00 273.27 ? 183 TRP A CG  1 
ATOM   167   C  CD1 . TRP A 1 184 ? 131.891 109.105 68.940  1.00 256.19 ? 183 TRP A CD1 1 
ATOM   168   C  CD2 . TRP A 1 184 ? 130.824 107.246 68.241  1.00 284.60 ? 183 TRP A CD2 1 
ATOM   169   N  NE1 . TRP A 1 184 ? 132.637 108.024 69.331  1.00 282.26 ? 183 TRP A NE1 1 
ATOM   170   C  CE2 . TRP A 1 184 ? 132.016 106.870 68.913  1.00 318.69 ? 183 TRP A CE2 1 
ATOM   171   C  CE3 . TRP A 1 184 ? 129.985 106.255 67.702  1.00 210.27 ? 183 TRP A CE3 1 
ATOM   172   C  CZ2 . TRP A 1 184 ? 132.388 105.528 69.063  1.00 290.32 ? 183 TRP A CZ2 1 
ATOM   173   C  CZ3 . TRP A 1 184 ? 130.360 104.932 67.850  1.00 294.54 ? 183 TRP A CZ3 1 
ATOM   174   C  CH2 . TRP A 1 184 ? 131.547 104.576 68.518  1.00 298.91 ? 183 TRP A CH2 1 
ATOM   175   N  N   . ALA A 1 185 ? 128.954 111.196 70.127  1.00 183.34 ? 184 ALA A N   1 
ATOM   176   C  CA  . ALA A 1 185 ? 129.233 111.721 71.463  1.00 297.14 ? 184 ALA A CA  1 
ATOM   177   C  C   . ALA A 1 185 ? 128.106 111.394 72.456  1.00 283.42 ? 184 ALA A C   1 
ATOM   178   O  O   . ALA A 1 185 ? 128.384 110.860 73.535  1.00 244.44 ? 184 ALA A O   1 
ATOM   179   C  CB  . ALA A 1 185 ? 129.498 113.214 71.409  1.00 312.33 ? 184 ALA A CB  1 
ATOM   180   N  N   . LEU A 1 186 ? 126.848 111.705 72.092  1.00 214.49 ? 185 LEU A N   1 
ATOM   181   C  CA  . LEU A 1 186 ? 125.717 111.512 72.987  1.00 179.65 ? 185 LEU A CA  1 
ATOM   182   C  C   . LEU A 1 186 ? 125.444 110.030 73.236  1.00 178.11 ? 185 LEU A C   1 
ATOM   183   O  O   . LEU A 1 186 ? 125.168 109.747 74.398  1.00 294.59 ? 185 LEU A O   1 
ATOM   184   C  CB  . LEU A 1 186 ? 124.444 112.201 72.468  1.00 239.69 ? 185 LEU A CB  1 
ATOM   185   C  CG  . LEU A 1 186 ? 124.363 113.728 72.601  1.00 300.88 ? 185 LEU A CG  1 
ATOM   186   C  CD1 . LEU A 1 186 ? 122.912 114.185 72.515  1.00 320.22 ? 185 LEU A CD1 1 
ATOM   187   C  CD2 . LEU A 1 186 ? 124.988 114.263 73.890  1.00 292.85 ? 185 LEU A CD2 1 
ATOM   188   N  N   . LEU A 1 187 ? 125.516 109.117 72.226  1.00 161.08 ? 186 LEU A N   1 
ATOM   189   C  CA  . LEU A 1 187 ? 125.529 107.659 72.460  1.00 172.76 ? 186 LEU A CA  1 
ATOM   190   C  C   . LEU A 1 187 ? 126.507 107.330 73.587  1.00 215.07 ? 186 LEU A C   1 
ATOM   191   O  O   . LEU A 1 187 ? 126.138 106.658 74.565  1.00 339.52 ? 186 LEU A O   1 
ATOM   192   C  CB  . LEU A 1 187 ? 125.990 106.769 71.281  1.00 216.43 ? 186 LEU A CB  1 
ATOM   193   C  CG  . LEU A 1 187 ? 126.212 105.271 71.647  1.00 185.72 ? 186 LEU A CG  1 
ATOM   194   C  CD1 . LEU A 1 187 ? 124.874 104.562 71.572  1.00 239.26 ? 186 LEU A CD1 1 
ATOM   195   C  CD2 . LEU A 1 187 ? 127.290 104.475 70.866  1.00 165.14 ? 186 LEU A CD2 1 
ATOM   196   N  N   . LEU A 1 188 ? 127.762 107.772 73.416  1.00 155.56 ? 187 LEU A N   1 
ATOM   197   C  CA  . LEU A 1 188 ? 128.810 107.382 74.333  1.00 190.68 ? 187 LEU A CA  1 
ATOM   198   C  C   . LEU A 1 188 ? 128.523 107.994 75.706  1.00 225.83 ? 187 LEU A C   1 
ATOM   199   O  O   . LEU A 1 188 ? 128.634 107.282 76.710  1.00 280.91 ? 187 LEU A O   1 
ATOM   200   C  CB  . LEU A 1 188 ? 130.172 107.812 73.788  1.00 224.94 ? 187 LEU A CB  1 
ATOM   201   C  CG  . LEU A 1 188 ? 131.344 107.175 74.540  1.00 295.28 ? 187 LEU A CG  1 
ATOM   202   C  CD1 . LEU A 1 188 ? 132.315 106.455 73.609  1.00 329.84 ? 187 LEU A CD1 1 
ATOM   203   C  CD2 . LEU A 1 188 ? 132.035 108.230 75.389  1.00 371.48 ? 187 LEU A CD2 1 
ATOM   204   N  N   . LEU A 1 189 ? 128.133 109.290 75.732  1.00 183.92 ? 188 LEU A N   1 
ATOM   205   C  CA  . LEU A 1 189 ? 127.744 110.010 76.952  1.00 232.65 ? 188 LEU A CA  1 
ATOM   206   C  C   . LEU A 1 189 ? 126.633 109.288 77.741  1.00 219.84 ? 188 LEU A C   1 
ATOM   207   O  O   . LEU A 1 189 ? 126.791 109.095 78.944  1.00 187.70 ? 188 LEU A O   1 
ATOM   208   C  CB  . LEU A 1 189 ? 127.324 111.443 76.588  1.00 256.41 ? 188 LEU A CB  1 
ATOM   209   C  CG  . LEU A 1 189 ? 127.182 112.426 77.758  1.00 380.92 ? 188 LEU A CG  1 
ATOM   210   C  CD1 . LEU A 1 189 ? 127.778 113.778 77.396  1.00 450.45 ? 188 LEU A CD1 1 
ATOM   211   C  CD2 . LEU A 1 189 ? 125.728 112.621 78.193  1.00 389.41 ? 188 LEU A CD2 1 
ATOM   212   N  N   . PHE A 1 190 ? 125.523 108.902 77.076  1.00 235.60 ? 189 PHE A N   1 
ATOM   213   C  CA  . PHE A 1 190 ? 124.399 108.175 77.674  1.00 183.92 ? 189 PHE A CA  1 
ATOM   214   C  C   . PHE A 1 190 ? 124.858 106.883 78.331  1.00 152.51 ? 189 PHE A C   1 
ATOM   215   O  O   . PHE A 1 190 ? 124.570 106.716 79.514  1.00 294.25 ? 189 PHE A O   1 
ATOM   216   C  CB  . PHE A 1 190 ? 123.363 107.766 76.629  1.00 249.47 ? 189 PHE A CB  1 
ATOM   217   C  CG  . PHE A 1 190 ? 122.454 106.596 76.920  1.00 211.74 ? 189 PHE A CG  1 
ATOM   218   C  CD1 . PHE A 1 190 ? 121.349 106.810 77.709  1.00 207.32 ? 189 PHE A CD1 1 
ATOM   219   C  CD2 . PHE A 1 190 ? 122.680 105.317 76.388  1.00 153.73 ? 189 PHE A CD2 1 
ATOM   220   C  CE1 . PHE A 1 190 ? 120.478 105.763 77.963  1.00 267.80 ? 189 PHE A CE1 1 
ATOM   221   C  CE2 . PHE A 1 190 ? 121.819 104.275 76.653  1.00 192.75 ? 189 PHE A CE2 1 
ATOM   222   C  CZ  . PHE A 1 190 ? 120.718 104.505 77.440  1.00 259.98 ? 189 PHE A CZ  1 
ATOM   223   N  N   . TRP A 1 191 ? 125.555 106.010 77.582  1.00 105.20 ? 190 TRP A N   1 
ATOM   224   C  CA  . TRP A 1 191 ? 126.099 104.776 78.133  1.00 159.52 ? 190 TRP A CA  1 
ATOM   225   C  C   . TRP A 1 191 ? 127.053 105.042 79.291  1.00 179.13 ? 190 TRP A C   1 
ATOM   226   O  O   . TRP A 1 191 ? 126.992 104.304 80.280  1.00 207.85 ? 190 TRP A O   1 
ATOM   227   C  CB  . TRP A 1 191 ? 126.807 103.912 77.090  1.00 169.00 ? 190 TRP A CB  1 
ATOM   228   C  CG  . TRP A 1 191 ? 125.801 103.164 76.290  1.00 178.72 ? 190 TRP A CG  1 
ATOM   229   C  CD1 . TRP A 1 191 ? 125.576 103.282 74.962  1.00 293.75 ? 190 TRP A CD1 1 
ATOM   230   C  CD2 . TRP A 1 191 ? 124.876 102.183 76.776  1.00 203.02 ? 190 TRP A CD2 1 
ATOM   231   N  NE1 . TRP A 1 191 ? 124.570 102.442 74.575  1.00 351.61 ? 190 TRP A NE1 1 
ATOM   232   C  CE2 . TRP A 1 191 ? 124.119 101.751 75.666  1.00 261.04 ? 190 TRP A CE2 1 
ATOM   233   C  CE3 . TRP A 1 191 ? 124.618 101.630 78.026  1.00 257.07 ? 190 TRP A CE3 1 
ATOM   234   C  CZ2 . TRP A 1 191 ? 123.116 100.789 75.763  1.00 209.77 ? 190 TRP A CZ2 1 
ATOM   235   C  CZ3 . TRP A 1 191 ? 123.629 100.678 78.124  1.00 291.18 ? 190 TRP A CZ3 1 
ATOM   236   C  CH2 . TRP A 1 191 ? 122.891 100.265 77.010  1.00 263.12 ? 190 TRP A CH2 1 
ATOM   237   N  N   . LEU A 1 192 ? 127.887 106.079 79.182  1.00 141.36 ? 191 LEU A N   1 
ATOM   238   C  CA  . LEU A 1 192 ? 128.756 106.429 80.289  1.00 206.44 ? 191 LEU A CA  1 
ATOM   239   C  C   . LEU A 1 192 ? 127.935 106.791 81.538  1.00 213.39 ? 191 LEU A C   1 
ATOM   240   O  O   . LEU A 1 192 ? 128.262 106.309 82.617  1.00 202.50 ? 191 LEU A O   1 
ATOM   241   C  CB  . LEU A 1 192 ? 129.700 107.562 79.868  1.00 253.28 ? 191 LEU A CB  1 
ATOM   242   C  CG  . LEU A 1 192 ? 130.928 107.748 80.752  1.00 355.74 ? 191 LEU A CG  1 
ATOM   243   C  CD1 . LEU A 1 192 ? 131.819 106.504 80.720  1.00 301.61 ? 191 LEU A CD1 1 
ATOM   244   C  CD2 . LEU A 1 192 ? 131.700 108.992 80.322  1.00 422.91 ? 191 LEU A CD2 1 
ATOM   245   N  N   . GLY A 1 193 ? 126.884 107.617 81.397  1.00 232.71 ? 192 GLY A N   1 
ATOM   246   C  CA  . GLY A 1 193 ? 126.011 108.047 82.494  1.00 219.64 ? 192 GLY A CA  1 
ATOM   247   C  C   . GLY A 1 193 ? 125.269 106.913 83.202  1.00 151.48 ? 192 GLY A C   1 
ATOM   248   O  O   . GLY A 1 193 ? 125.201 106.896 84.428  1.00 240.18 ? 192 GLY A O   1 
ATOM   249   N  N   . TRP A 1 194 ? 124.727 105.970 82.425  1.00 142.73 ? 193 TRP A N   1 
ATOM   250   C  CA  . TRP A 1 194 ? 124.105 104.739 82.908  1.00 143.95 ? 193 TRP A CA  1 
ATOM   251   C  C   . TRP A 1 194 ? 125.136 103.854 83.588  1.00 134.89 ? 193 TRP A C   1 
ATOM   252   O  O   . TRP A 1 194 ? 124.813 103.301 84.636  1.00 199.05 ? 193 TRP A O   1 
ATOM   253   C  CB  . TRP A 1 194 ? 123.450 104.032 81.724  1.00 139.77 ? 193 TRP A CB  1 
ATOM   254   C  CG  . TRP A 1 194 ? 122.668 102.749 81.798  1.00 117.81 ? 193 TRP A CG  1 
ATOM   255   C  CD1 . TRP A 1 194 ? 121.325 102.633 81.545  1.00 107.95 ? 193 TRP A CD1 1 
ATOM   256   C  CD2 . TRP A 1 194 ? 123.160 101.415 82.027  1.00 121.05 ? 193 TRP A CD2 1 
ATOM   257   N  NE1 . TRP A 1 194 ? 120.905 101.331 81.617  1.00 89.81  ? 193 TRP A NE1 1 
ATOM   258   C  CE2 . TRP A 1 194 ? 122.004 100.558 81.910  1.00 127.53 ? 193 TRP A CE2 1 
ATOM   259   C  CE3 . TRP A 1 194 ? 124.441 100.878 82.325  1.00 83.79  ? 193 TRP A CE3 1 
ATOM   260   C  CZ2 . TRP A 1 194 ? 122.108 99.174  82.080  1.00 128.28 ? 193 TRP A CZ2 1 
ATOM   261   C  CZ3 . TRP A 1 194 ? 124.539 99.512  82.477  1.00 143.40 ? 193 TRP A CZ3 1 
ATOM   262   C  CH2 . TRP A 1 194 ? 123.386 98.682  82.348  1.00 202.74 ? 193 TRP A CH2 1 
ATOM   263   N  N   . LEU A 1 195 ? 126.343 103.717 83.022  1.00 118.54 ? 194 LEU A N   1 
ATOM   264   C  CA  . LEU A 1 195 ? 127.344 102.892 83.676  1.00 152.27 ? 194 LEU A CA  1 
ATOM   265   C  C   . LEU A 1 195 ? 127.785 103.557 84.970  1.00 158.30 ? 194 LEU A C   1 
ATOM   266   O  O   . LEU A 1 195 ? 128.056 102.824 85.919  1.00 138.03 ? 194 LEU A O   1 
ATOM   267   C  CB  . LEU A 1 195 ? 128.540 102.627 82.762  1.00 164.22 ? 194 LEU A CB  1 
ATOM   268   C  CG  . LEU A 1 195 ? 128.344 101.428 81.853  1.00 236.89 ? 194 LEU A CG  1 
ATOM   269   C  CD1 . LEU A 1 195 ? 129.316 101.453 80.684  1.00 344.65 ? 194 LEU A CD1 1 
ATOM   270   C  CD2 . LEU A 1 195 ? 128.497 100.146 82.655  1.00 227.79 ? 194 LEU A CD2 1 
ATOM   271   N  N   . GLY A 1 196 ? 127.872 104.900 84.990  1.00 164.92 ? 195 GLY A N   1 
ATOM   272   C  CA  . GLY A 1 196 ? 128.180 105.658 86.198  1.00 259.92 ? 195 GLY A CA  1 
ATOM   273   C  C   . GLY A 1 196 ? 127.183 105.397 87.328  1.00 205.90 ? 195 GLY A C   1 
ATOM   274   O  O   . GLY A 1 196 ? 127.569 105.121 88.465  1.00 237.48 ? 195 GLY A O   1 
ATOM   275   N  N   . MET A 1 197 ? 125.905 105.498 86.978  1.00 174.05 ? 196 MET A N   1 
ATOM   276   C  CA  . MET A 1 197 ? 124.794 105.141 87.839  1.00 146.98 ? 196 MET A CA  1 
ATOM   277   C  C   . MET A 1 197 ? 124.922 103.677 88.276  1.00 118.88 ? 196 MET A C   1 
ATOM   278   O  O   . MET A 1 197 ? 124.666 103.431 89.444  1.00 146.89 ? 196 MET A O   1 
ATOM   279   C  CB  . MET A 1 197 ? 123.492 105.426 87.073  1.00 160.77 ? 196 MET A CB  1 
ATOM   280   C  CG  . MET A 1 197 ? 122.168 104.884 87.603  1.00 175.25 ? 196 MET A CG  1 
ATOM   281   S  SD  . MET A 1 197 ? 120.806 105.216 86.449  1.00 185.82 ? 196 MET A SD  1 
ATOM   282   C  CE  . MET A 1 197 ? 120.642 107.006 86.656  1.00 195.08 ? 196 MET A CE  1 
ATOM   283   N  N   . LEU A 1 198 ? 125.313 102.723 87.400  1.00 112.42 ? 197 LEU A N   1 
ATOM   284   C  CA  . LEU A 1 198 ? 125.440 101.319 87.787  1.00 127.05 ? 197 LEU A CA  1 
ATOM   285   C  C   . LEU A 1 198 ? 126.555 101.181 88.811  1.00 150.49 ? 197 LEU A C   1 
ATOM   286   O  O   . LEU A 1 198 ? 126.346 100.513 89.822  1.00 212.02 ? 197 LEU A O   1 
ATOM   287   C  CB  . LEU A 1 198 ? 125.724 100.341 86.636  1.00 130.80 ? 197 LEU A CB  1 
ATOM   288   C  CG  . LEU A 1 198 ? 125.923 98.874  87.084  1.00 147.27 ? 197 LEU A CG  1 
ATOM   289   C  CD1 . LEU A 1 198 ? 124.610 98.276  87.567  1.00 276.31 ? 197 LEU A CD1 1 
ATOM   290   C  CD2 . LEU A 1 198 ? 126.475 97.961  86.020  1.00 186.30 ? 197 LEU A CD2 1 
ATOM   291   N  N   . ALA A 1 199 ? 127.706 101.797 88.549  1.00 144.43 ? 198 ALA A N   1 
ATOM   292   C  CA  . ALA A 1 199 ? 128.784 101.761 89.516  1.00 183.54 ? 198 ALA A CA  1 
ATOM   293   C  C   . ALA A 1 199 ? 128.311 102.396 90.822  1.00 184.26 ? 198 ALA A C   1 
ATOM   294   O  O   . ALA A 1 199 ? 128.559 101.810 91.867  1.00 242.13 ? 198 ALA A O   1 
ATOM   295   C  CB  . ALA A 1 199 ? 130.006 102.465 88.988  1.00 257.60 ? 198 ALA A CB  1 
ATOM   296   N  N   . GLY A 1 200 ? 127.648 103.571 90.747  1.00 172.09 ? 199 GLY A N   1 
ATOM   297   C  CA  . GLY A 1 200 ? 127.081 104.295 91.880  1.00 198.84 ? 199 GLY A CA  1 
ATOM   298   C  C   . GLY A 1 200 ? 126.132 103.456 92.735  1.00 173.68 ? 199 GLY A C   1 
ATOM   299   O  O   . GLY A 1 200 ? 126.266 103.416 93.948  1.00 149.08 ? 199 GLY A O   1 
ATOM   300   N  N   . ALA A 1 201 ? 125.176 102.785 92.093  1.00 164.26 ? 200 ALA A N   1 
ATOM   301   C  CA  . ALA A 1 201 ? 124.238 101.949 92.815  1.00 145.74 ? 200 ALA A CA  1 
ATOM   302   C  C   . ALA A 1 201 ? 124.995 100.767 93.417  1.00 166.07 ? 200 ALA A C   1 
ATOM   303   O  O   . ALA A 1 201 ? 124.672 100.449 94.543  1.00 236.49 ? 200 ALA A O   1 
ATOM   304   C  CB  . ALA A 1 201 ? 123.070 101.529 91.937  1.00 133.86 ? 200 ALA A CB  1 
ATOM   305   N  N   . VAL A 1 202 ? 125.980 100.134 92.734  1.00 117.30 ? 201 VAL A N   1 
ATOM   306   C  CA  . VAL A 1 202 ? 126.783 99.065  93.344  1.00 150.15 ? 201 VAL A CA  1 
ATOM   307   C  C   . VAL A 1 202 ? 127.575 99.609  94.547  1.00 174.23 ? 201 VAL A C   1 
ATOM   308   O  O   . VAL A 1 202 ? 127.649 98.933  95.571  1.00 190.34 ? 201 VAL A O   1 
ATOM   309   C  CB  . VAL A 1 202 ? 127.710 98.342  92.352  1.00 187.03 ? 201 VAL A CB  1 
ATOM   310   C  CG1 . VAL A 1 202 ? 128.652 97.360  93.039  1.00 220.80 ? 201 VAL A CG1 1 
ATOM   311   C  CG2 . VAL A 1 202 ? 126.914 97.605  91.293  1.00 250.07 ? 201 VAL A CG2 1 
ATOM   312   N  N   . VAL A 1 203 ? 128.129 100.823 94.433  1.00 137.36 ? 202 VAL A N   1 
ATOM   313   C  CA  . VAL A 1 203 ? 128.792 101.485 95.544  1.00 148.50 ? 202 VAL A CA  1 
ATOM   314   C  C   . VAL A 1 203 ? 127.824 101.594 96.724  1.00 174.82 ? 202 VAL A C   1 
ATOM   315   O  O   . VAL A 1 203 ? 128.227 101.235 97.829  1.00 222.13 ? 202 VAL A O   1 
ATOM   316   C  CB  . VAL A 1 203 ? 129.391 102.854 95.125  1.00 244.72 ? 202 VAL A CB  1 
ATOM   317   C  CG1 . VAL A 1 203 ? 129.577 103.895 96.242  1.00 255.24 ? 202 VAL A CG1 1 
ATOM   318   C  CG2 . VAL A 1 203 ? 130.713 102.625 94.402  1.00 336.89 ? 202 VAL A CG2 1 
ATOM   319   N  N   . ILE A 1 204 ? 126.585 102.085 96.504  1.00 161.54 ? 203 ILE A N   1 
ATOM   320   C  CA  . ILE A 1 204 ? 125.606 102.318 97.572  1.00 168.37 ? 203 ILE A CA  1 
ATOM   321   C  C   . ILE A 1 204 ? 125.282 100.991 98.250  1.00 113.34 ? 203 ILE A C   1 
ATOM   322   O  O   . ILE A 1 204 ? 125.266 100.938 99.474  1.00 171.90 ? 203 ILE A O   1 
ATOM   323   C  CB  . ILE A 1 204 ? 124.370 103.114 97.054  1.00 154.44 ? 203 ILE A CB  1 
ATOM   324   C  CG1 . ILE A 1 204 ? 124.789 104.564 96.814  1.00 198.79 ? 203 ILE A CG1 1 
ATOM   325   C  CG2 . ILE A 1 204 ? 123.158 103.108 97.962  1.00 127.36 ? 203 ILE A CG2 1 
ATOM   326   C  CD1 . ILE A 1 204 ? 123.725 105.427 96.227  1.00 214.85 ? 203 ILE A CD1 1 
ATOM   327   N  N   . ILE A 1 205 ? 125.030 99.958  97.464  1.00 91.00  ? 204 ILE A N   1 
ATOM   328   C  CA  . ILE A 1 205 ? 124.669 98.650  97.979  1.00 117.71 ? 204 ILE A CA  1 
ATOM   329   C  C   . ILE A 1 205 ? 125.780 98.103  98.881  1.00 165.42 ? 204 ILE A C   1 
ATOM   330   O  O   . ILE A 1 205 ? 125.467 97.549  99.935  1.00 261.72 ? 204 ILE A O   1 
ATOM   331   C  CB  . ILE A 1 205 ? 124.315 97.679  96.825  1.00 145.76 ? 204 ILE A CB  1 
ATOM   332   C  CG1 . ILE A 1 205 ? 123.005 98.129  96.126  1.00 123.00 ? 204 ILE A CG1 1 
ATOM   333   C  CG2 . ILE A 1 205 ? 124.373 96.181  97.244  1.00 109.18 ? 204 ILE A CG2 1 
ATOM   334   C  CD1 . ILE A 1 205 ? 121.726 97.961  96.856  1.00 139.90 ? 204 ILE A CD1 1 
ATOM   335   N  N   . VAL A 1 206 ? 127.052 98.248  98.494  1.00 141.89 ? 205 VAL A N   1 
ATOM   336   C  CA  . VAL A 1 206 ? 128.147 97.749  99.323  1.00 234.40 ? 205 VAL A CA  1 
ATOM   337   C  C   . VAL A 1 206 ? 128.375 98.684  100.522 1.00 216.45 ? 205 VAL A C   1 
ATOM   338   O  O   . VAL A 1 206 ? 128.490 98.198  101.654 1.00 229.55 ? 205 VAL A O   1 
ATOM   339   C  CB  . VAL A 1 206 ? 129.414 97.505  98.475  1.00 265.76 ? 205 VAL A CB  1 
ATOM   340   C  CG1 . VAL A 1 206 ? 130.630 97.083  99.303  1.00 284.17 ? 205 VAL A CG1 1 
ATOM   341   C  CG2 . VAL A 1 206 ? 129.126 96.468  97.391  1.00 241.82 ? 205 VAL A CG2 1 
ATOM   342   N  N   . ARG A 1 207 ? 128.427 100.008 100.292 1.00 138.29 ? 206 ARG A N   1 
ATOM   343   C  CA  . ARG A 1 207 ? 128.717 100.970 101.352 1.00 211.60 ? 206 ARG A CA  1 
ATOM   344   C  C   . ARG A 1 207 ? 127.407 101.347 102.065 1.00 232.98 ? 206 ARG A C   1 
ATOM   345   O  O   . ARG A 1 207 ? 127.008 102.519 102.088 1.00 235.76 ? 206 ARG A O   1 
ATOM   346   C  CB  . ARG A 1 207 ? 129.454 102.184 100.752 1.00 320.64 ? 206 ARG A CB  1 
ATOM   347   C  CG  . ARG A 1 207 ? 130.227 103.065 101.734 1.00 343.94 ? 206 ARG A CG  1 
ATOM   348   C  CD  . ARG A 1 207 ? 129.853 104.549 101.780 1.00 320.75 ? 206 ARG A CD  1 
ATOM   349   N  NE  . ARG A 1 207 ? 129.722 105.250 100.495 1.00 314.83 ? 206 ARG A NE  1 
ATOM   350   C  CZ  . ARG A 1 207 ? 128.566 105.566 99.890  1.00 340.13 ? 206 ARG A CZ  1 
ATOM   351   N  NH1 . ARG A 1 207 ? 128.563 106.257 98.756  1.00 278.84 ? 206 ARG A NH1 1 
ATOM   352   N  NH2 . ARG A 1 207 ? 127.404 105.195 100.412 1.00 352.73 ? 206 ARG A NH2 1 
ATOM   353   N  N   . ALA A 1 208 ? 126.746 100.335 102.659 1.00 246.09 ? 207 ALA A N   1 
ATOM   354   C  CA  . ALA A 1 208 ? 125.473 100.489 103.352 1.00 258.79 ? 207 ALA A CA  1 
ATOM   355   C  C   . ALA A 1 208 ? 125.358 99.431  104.453 1.00 248.47 ? 207 ALA A C   1 
ATOM   356   O  O   . ALA A 1 208 ? 125.927 98.334  104.305 1.00 166.80 ? 207 ALA A O   1 
ATOM   357   C  CB  . ALA A 1 208 ? 124.320 100.393 102.379 1.00 252.02 ? 207 ALA A CB  1 
ATOM   358   N  N   . PRO A 1 209 ? 124.620 99.738  105.564 1.00 232.55 ? 208 PRO A N   1 
ATOM   359   C  CA  . PRO A 1 209 ? 124.586 98.867  106.743 1.00 171.15 ? 208 PRO A CA  1 
ATOM   360   C  C   . PRO A 1 209 ? 123.841 97.564  106.461 1.00 155.43 ? 208 PRO A C   1 
ATOM   361   O  O   . PRO A 1 209 ? 122.754 97.611  105.871 1.00 202.69 ? 208 PRO A O   1 
ATOM   362   C  CB  . PRO A 1 209 ? 123.818 99.723  107.772 1.00 244.82 ? 208 PRO A CB  1 
ATOM   363   C  CG  . PRO A 1 209 ? 122.867 100.571 106.929 1.00 244.58 ? 208 PRO A CG  1 
ATOM   364   C  CD  . PRO A 1 209 ? 123.762 100.938 105.757 1.00 253.38 ? 208 PRO A CD  1 
ATOM   365   N  N   . ARG A 1 210 ? 124.418 96.415  106.871 1.00 140.59 ? 209 ARG A N   1 
ATOM   366   C  CA  . ARG A 1 210 ? 123.803 95.099  106.656 1.00 157.43 ? 209 ARG A CA  1 
ATOM   367   C  C   . ARG A 1 210 ? 122.688 94.842  107.694 1.00 156.05 ? 209 ARG A C   1 
ATOM   368   O  O   . ARG A 1 210 ? 122.651 95.523  108.713 1.00 228.98 ? 209 ARG A O   1 
ATOM   369   C  CB  . ARG A 1 210 ? 124.922 94.045  106.616 1.00 182.38 ? 209 ARG A CB  1 
ATOM   370   C  CG  . ARG A 1 210 ? 125.957 94.246  105.507 1.00 221.74 ? 209 ARG A CG  1 
ATOM   371   C  CD  . ARG A 1 210 ? 125.456 94.265  104.058 1.00 212.13 ? 209 ARG A CD  1 
ATOM   372   N  NE  . ARG A 1 210 ? 124.664 93.089  103.676 1.00 234.06 ? 209 ARG A NE  1 
ATOM   373   C  CZ  . ARG A 1 210 ? 125.142 91.911  103.260 1.00 324.09 ? 209 ARG A CZ  1 
ATOM   374   N  NH1 . ARG A 1 210 ? 124.326 90.876  103.138 1.00 359.11 ? 209 ARG A NH1 1 
ATOM   375   N  NH2 . ARG A 1 210 ? 126.427 91.755  102.981 1.00 340.51 ? 209 ARG A NH2 1 
ATOM   376   N  N   . CYS A 1 211 ? 121.772 93.883  107.440 1.00 159.53 ? 210 CYS A N   1 
ATOM   377   C  CA  . CYS A 1 211 ? 120.847 93.396  108.454 1.00 190.82 ? 210 CYS A CA  1 
ATOM   378   C  C   . CYS A 1 211 ? 121.583 92.545  109.512 1.00 220.12 ? 210 CYS A C   1 
ATOM   379   O  O   . CYS A 1 211 ? 122.653 91.986  109.270 1.00 222.00 ? 210 CYS A O   1 
ATOM   380   C  CB  . CYS A 1 211 ? 119.746 92.479  107.916 1.00 186.69 ? 210 CYS A CB  1 
ATOM   381   S  SG  . CYS A 1 211 ? 118.748 92.927  106.460 1.00 216.08 ? 210 CYS A SG  1 
ATOM   382   N  N   . ARG A 1 212 ? 120.974 92.444  110.701 1.00 208.28 ? 211 ARG A N   1 
ATOM   383   C  CA  . ARG A 1 212 ? 121.397 91.585  111.796 1.00 151.56 ? 211 ARG A CA  1 
ATOM   384   C  C   . ARG A 1 212 ? 120.662 90.253  111.660 1.00 138.19 ? 211 ARG A C   1 
ATOM   385   O  O   . ARG A 1 212 ? 119.442 90.250  111.454 1.00 137.04 ? 211 ARG A O   1 
ATOM   386   C  CB  . ARG A 1 212 ? 121.007 92.318  113.082 1.00 199.50 ? 211 ARG A CB  1 
ATOM   387   C  CG  . ARG A 1 212 ? 121.512 91.741  114.392 1.00 228.14 ? 211 ARG A CG  1 
ATOM   388   C  CD  . ARG A 1 212 ? 121.088 92.684  115.509 1.00 208.32 ? 211 ARG A CD  1 
ATOM   389   N  NE  . ARG A 1 212 ? 121.379 92.131  116.824 1.00 207.39 ? 211 ARG A NE  1 
ATOM   390   C  CZ  . ARG A 1 212 ? 121.044 92.684  117.991 1.00 257.93 ? 211 ARG A CZ  1 
ATOM   391   N  NH1 . ARG A 1 212 ? 121.387 92.067  119.108 1.00 328.65 ? 211 ARG A NH1 1 
ATOM   392   N  NH2 . ARG A 1 212 ? 120.360 93.824  118.055 1.00 225.08 ? 211 ARG A NH2 1 
ATOM   393   N  N   . GLU A 1 213 ? 121.370 89.122  111.764 1.00 132.37 ? 212 GLU A N   1 
ATOM   394   C  CA  . GLU A 1 213 ? 120.726 87.801  111.642 1.00 155.37 ? 212 GLU A CA  1 
ATOM   395   C  C   . GLU A 1 213 ? 119.656 87.625  112.722 1.00 150.30 ? 212 GLU A C   1 
ATOM   396   O  O   . GLU A 1 213 ? 119.913 87.998  113.864 1.00 264.30 ? 212 GLU A O   1 
ATOM   397   C  CB  . GLU A 1 213 ? 121.750 86.651  111.659 1.00 215.50 ? 212 GLU A CB  1 
ATOM   398   C  CG  . GLU A 1 213 ? 122.777 86.651  112.805 1.00 261.76 ? 212 GLU A CG  1 
ATOM   399   C  CD  . GLU A 1 213 ? 122.416 85.912  114.085 1.00 329.99 ? 212 GLU A CD  1 
ATOM   400   O  OE1 . GLU A 1 213 ? 121.527 85.041  114.047 1.00 359.08 ? 212 GLU A OE1 1 
ATOM   401   O  OE2 . GLU A 1 213 ? 123.034 86.219  115.127 1.00 349.51 ? 212 GLU A OE2 1 
ATOM   402   N  N   . LEU A 1 214 ? 118.471 87.086  112.373 1.00 145.12 ? 213 LEU A N   1 
ATOM   403   C  CA  . LEU A 1 214 ? 117.383 86.882  113.333 1.00 122.90 ? 213 LEU A CA  1 
ATOM   404   C  C   . LEU A 1 214 ? 117.787 85.742  114.244 1.00 130.23 ? 213 LEU A C   1 
ATOM   405   O  O   . LEU A 1 214 ? 118.157 84.681  113.736 1.00 200.05 ? 213 LEU A O   1 
ATOM   406   C  CB  . LEU A 1 214 ? 116.048 86.487  112.679 1.00 131.91 ? 213 LEU A CB  1 
ATOM   407   C  CG  . LEU A 1 214 ? 115.453 87.441  111.637 1.00 175.65 ? 213 LEU A CG  1 
ATOM   408   C  CD1 . LEU A 1 214 ? 113.960 87.110  111.448 1.00 148.39 ? 213 LEU A CD1 1 
ATOM   409   C  CD2 . LEU A 1 214 ? 115.677 88.935  111.980 1.00 184.46 ? 213 LEU A CD2 1 
ATOM   410   N  N   . PRO A 1 215 ? 117.743 85.905  115.582 1.00 140.21 ? 214 PRO A N   1 
ATOM   411   C  CA  . PRO A 1 215 ? 118.146 84.809  116.475 1.00 169.13 ? 214 PRO A CA  1 
ATOM   412   C  C   . PRO A 1 215 ? 117.111 83.698  116.340 1.00 186.25 ? 214 PRO A C   1 
ATOM   413   O  O   . PRO A 1 215 ? 115.930 84.004  116.139 1.00 115.80 ? 214 PRO A O   1 
ATOM   414   C  CB  . PRO A 1 215 ? 118.138 85.453  117.855 1.00 255.69 ? 214 PRO A CB  1 
ATOM   415   C  CG  . PRO A 1 215 ? 117.152 86.614  117.698 1.00 249.28 ? 214 PRO A CG  1 
ATOM   416   C  CD  . PRO A 1 215 ? 117.309 87.129  116.284 1.00 141.01 ? 214 PRO A CD  1 
ATOM   417   N  N   . ALA A 1 216 ? 117.558 82.434  116.403 1.00 212.21 ? 215 ALA A N   1 
ATOM   418   C  CA  . ALA A 1 216 ? 116.654 81.307  116.167 1.00 242.81 ? 215 ALA A CA  1 
ATOM   419   C  C   . ALA A 1 216 ? 115.672 81.280  117.316 1.00 210.49 ? 215 ALA A C   1 
ATOM   420   O  O   . ALA A 1 216 ? 116.159 81.341  118.437 1.00 243.02 ? 215 ALA A O   1 
ATOM   421   C  CB  . ALA A 1 216 ? 117.397 80.000  116.094 1.00 295.32 ? 215 ALA A CB  1 
ATOM   422   N  N   . GLN A 1 217 ? 114.351 81.227  117.058 1.00 185.54 ? 216 GLN A N   1 
ATOM   423   C  CA  . GLN A 1 217 ? 113.380 81.452  118.135 1.00 187.22 ? 216 GLN A CA  1 
ATOM   424   C  C   . GLN A 1 217 ? 112.543 80.180  118.290 1.00 128.27 ? 216 GLN A C   1 
ATOM   425   O  O   . GLN A 1 217 ? 111.843 79.733  117.390 1.00 141.48 ? 216 GLN A O   1 
ATOM   426   C  CB  . GLN A 1 217 ? 112.537 82.734  117.951 1.00 164.00 ? 216 GLN A CB  1 
ATOM   427   C  CG  . GLN A 1 217 ? 111.679 82.775  116.690 1.00 248.26 ? 216 GLN A CG  1 
ATOM   428   C  CD  . GLN A 1 217 ? 110.940 84.084  116.535 1.00 323.67 ? 216 GLN A CD  1 
ATOM   429   O  OE1 . GLN A 1 217 ? 110.821 84.855  117.491 1.00 306.41 ? 216 GLN A OE1 1 
ATOM   430   N  NE2 . GLN A 1 217 ? 110.449 84.342  115.326 1.00 331.55 ? 216 GLN A NE2 1 
ATOM   431   N  N   . LYS A 1 218 ? 112.623 79.611  119.497 1.00 141.29 ? 217 LYS A N   1 
ATOM   432   C  CA  . LYS A 1 218 ? 111.763 78.500  119.883 1.00 143.25 ? 217 LYS A CA  1 
ATOM   433   C  C   . LYS A 1 218 ? 110.324 78.999  119.961 1.00 122.11 ? 217 LYS A C   1 
ATOM   434   O  O   . LYS A 1 218 ? 110.075 80.207  120.088 1.00 183.89 ? 217 LYS A O   1 
ATOM   435   C  CB  . LYS A 1 218 ? 112.292 77.948  121.214 1.00 149.97 ? 217 LYS A CB  1 
ATOM   436   C  CG  . LYS A 1 218 ? 113.756 77.492  121.159 1.00 179.04 ? 217 LYS A CG  1 
ATOM   437   C  CD  . LYS A 1 218 ? 114.045 76.696  119.886 1.00 221.18 ? 217 LYS A CD  1 
ATOM   438   C  CE  . LYS A 1 218 ? 115.288 75.852  119.803 1.00 270.89 ? 217 LYS A CE  1 
ATOM   439   N  NZ  . LYS A 1 218 ? 115.315 75.212  118.466 1.00 309.61 ? 217 LYS A NZ  1 
ATOM   440   N  N   . TRP A 1 219 ? 109.371 78.089  119.910 1.00 91.35  ? 218 TRP A N   1 
ATOM   441   C  CA  . TRP A 1 219 ? 108.003 78.557  119.898 1.00 105.80 ? 218 TRP A CA  1 
ATOM   442   C  C   . TRP A 1 219 ? 107.633 79.433  121.089 1.00 85.96  ? 218 TRP A C   1 
ATOM   443   O  O   . TRP A 1 219 ? 106.916 80.411  120.926 1.00 82.43  ? 218 TRP A O   1 
ATOM   444   C  CB  . TRP A 1 219 ? 107.064 77.367  119.828 1.00 138.16 ? 218 TRP A CB  1 
ATOM   445   C  CG  . TRP A 1 219 ? 107.158 76.332  120.908 1.00 86.93  ? 218 TRP A CG  1 
ATOM   446   C  CD1 . TRP A 1 219 ? 107.841 75.154  120.859 1.00 133.00 ? 218 TRP A CD1 1 
ATOM   447   C  CD2 . TRP A 1 219 ? 106.464 76.341  122.159 1.00 77.76  ? 218 TRP A CD2 1 
ATOM   448   N  NE1 . TRP A 1 219 ? 107.644 74.440  122.011 1.00 138.16 ? 218 TRP A NE1 1 
ATOM   449   C  CE2 . TRP A 1 219 ? 106.800 75.142  122.822 1.00 91.39  ? 218 TRP A CE2 1 
ATOM   450   C  CE3 . TRP A 1 219 ? 105.590 77.234  122.780 1.00 90.12  ? 218 TRP A CE3 1 
ATOM   451   C  CZ2 . TRP A 1 219 ? 106.289 74.829  124.074 1.00 127.77 ? 218 TRP A CZ2 1 
ATOM   452   C  CZ3 . TRP A 1 219 ? 105.081 76.922  124.020 1.00 119.15 ? 218 TRP A CZ3 1 
ATOM   453   C  CH2 . TRP A 1 219 ? 105.419 75.736  124.654 1.00 113.60 ? 218 TRP A CH2 1 
ATOM   454   N  N   . TRP A 1 220 ? 108.130 79.106  122.269 1.00 79.34  ? 219 TRP A N   1 
ATOM   455   C  CA  . TRP A 1 220 ? 107.802 79.872  123.459 1.00 79.57  ? 219 TRP A CA  1 
ATOM   456   C  C   . TRP A 1 220 ? 108.415 81.278  123.511 1.00 65.72  ? 219 TRP A C   1 
ATOM   457   O  O   . TRP A 1 220 ? 108.047 82.094  124.362 1.00 79.37  ? 219 TRP A O   1 
ATOM   458   C  CB  . TRP A 1 220 ? 108.162 79.097  124.738 1.00 71.95  ? 219 TRP A CB  1 
ATOM   459   C  CG  . TRP A 1 220 ? 109.613 78.855  124.952 1.00 81.81  ? 219 TRP A CG  1 
ATOM   460   C  CD1 . TRP A 1 220 ? 110.481 79.680  125.570 1.00 101.71 ? 219 TRP A CD1 1 
ATOM   461   C  CD2 . TRP A 1 220 ? 110.357 77.683  124.565 1.00 99.94  ? 219 TRP A CD2 1 
ATOM   462   N  NE1 . TRP A 1 220 ? 111.724 79.107  125.585 1.00 141.48 ? 219 TRP A NE1 1 
ATOM   463   C  CE2 . TRP A 1 220 ? 111.673 77.885  124.982 1.00 132.08 ? 219 TRP A CE2 1 
ATOM   464   C  CE3 . TRP A 1 220 ? 110.049 76.491  123.913 1.00 104.03 ? 219 TRP A CE3 1 
ATOM   465   C  CZ2 . TRP A 1 220 ? 112.667 76.934  124.761 1.00 204.93 ? 219 TRP A CZ2 1 
ATOM   466   C  CZ3 . TRP A 1 220 ? 111.013 75.540  123.688 1.00 127.24 ? 219 TRP A CZ3 1 
ATOM   467   C  CH2 . TRP A 1 220 ? 112.314 75.763  124.114 1.00 186.22 ? 219 TRP A CH2 1 
ATOM   468   N  N   . HIS A 1 221 ? 109.331 81.637  122.652 1.00 56.33  ? 220 HIS A N   1 
ATOM   469   C  CA  . HIS A 1 221 ? 109.573 83.068  122.519 1.00 83.28  ? 220 HIS A CA  1 
ATOM   470   C  C   . HIS A 1 221 ? 108.394 83.838  121.908 1.00 86.95  ? 220 HIS A C   1 
ATOM   471   O  O   . HIS A 1 221 ? 108.268 85.022  122.162 1.00 125.51 ? 220 HIS A O   1 
ATOM   472   C  CB  . HIS A 1 221 ? 110.832 83.399  121.686 1.00 112.65 ? 220 HIS A CB  1 
ATOM   473   C  CG  . HIS A 1 221 ? 112.078 82.810  122.288 1.00 138.83 ? 220 HIS A CG  1 
ATOM   474   N  ND1 . HIS A 1 221 ? 113.324 83.009  121.733 1.00 164.66 ? 220 HIS A ND1 1 
ATOM   475   C  CD2 . HIS A 1 221 ? 112.261 82.000  123.408 1.00 88.76  ? 220 HIS A CD2 1 
ATOM   476   C  CE1 . HIS A 1 221 ? 114.209 82.362  122.513 1.00 196.96 ? 220 HIS A CE1 1 
ATOM   477   N  NE2 . HIS A 1 221 ? 113.588 81.727  123.507 1.00 112.99 ? 220 HIS A NE2 1 
ATOM   478   N  N   . THR A 1 222 ? 107.540 83.232  121.084 1.00 89.66  ? 221 THR A N   1 
ATOM   479   C  CA  . THR A 1 222 ? 106.726 83.982  120.135 1.00 100.19 ? 221 THR A CA  1 
ATOM   480   C  C   . THR A 1 222 ? 105.439 84.524  120.754 1.00 112.59 ? 221 THR A C   1 
ATOM   481   O  O   . THR A 1 222 ? 104.620 85.091  120.005 1.00 142.30 ? 221 THR A O   1 
ATOM   482   C  CB  . THR A 1 222 ? 106.365 83.163  118.885 1.00 143.60 ? 221 THR A CB  1 
ATOM   483   O  OG1 . THR A 1 222 ? 105.581 82.030  119.262 1.00 179.88 ? 221 THR A OG1 1 
ATOM   484   C  CG2 . THR A 1 222 ? 107.598 82.706  118.125 1.00 251.61 ? 221 THR A CG2 1 
ATOM   485   N  N   . GLY A 1 223 ? 105.237 84.379  122.089 1.00 95.81  ? 222 GLY A N   1 
ATOM   486   C  CA  . GLY A 1 223 ? 104.087 85.000  122.741 1.00 89.57  ? 222 GLY A CA  1 
ATOM   487   C  C   . GLY A 1 223 ? 103.724 84.290  124.021 1.00 78.79  ? 222 GLY A C   1 
ATOM   488   O  O   . GLY A 1 223 ? 104.468 83.402  124.461 1.00 100.20 ? 222 GLY A O   1 
ATOM   489   N  N   . ALA A 1 224 ? 102.576 84.690  124.576 1.00 65.65  ? 223 ALA A N   1 
ATOM   490   C  CA  . ALA A 1 224 ? 102.247 84.335  125.957 1.00 79.89  ? 223 ALA A CA  1 
ATOM   491   C  C   . ALA A 1 224 ? 101.828 82.862  126.191 1.00 60.53  ? 223 ALA A C   1 
ATOM   492   O  O   . ALA A 1 224 ? 101.064 82.318  125.464 1.00 90.63  ? 223 ALA A O   1 
ATOM   493   C  CB  . ALA A 1 224 ? 101.135 85.237  126.363 1.00 93.63  ? 223 ALA A CB  1 
ATOM   494   N  N   . LEU A 1 225 ? 102.321 82.208  127.203 1.00 49.12  ? 224 LEU A N   1 
ATOM   495   C  CA  . LEU A 1 225 ? 101.741 80.984  127.715 1.00 64.58  ? 224 LEU A CA  1 
ATOM   496   C  C   . LEU A 1 225 ? 100.517 81.287  128.571 1.00 70.83  ? 224 LEU A C   1 
ATOM   497   O  O   . LEU A 1 225 ? 100.111 82.446  128.701 1.00 75.86  ? 224 LEU A O   1 
ATOM   498   C  CB  . LEU A 1 225 ? 102.700 80.243  128.667 1.00 71.32  ? 224 LEU A CB  1 
ATOM   499   C  CG  . LEU A 1 225 ? 104.082 80.045  128.093 1.00 82.54  ? 224 LEU A CG  1 
ATOM   500   C  CD1 . LEU A 1 225 ? 104.872 79.113  128.969 1.00 92.14  ? 224 LEU A CD1 1 
ATOM   501   C  CD2 . LEU A 1 225 ? 103.977 79.506  126.664 1.00 103.61 ? 224 LEU A CD2 1 
ATOM   502   N  N   . TYR A 1 226 ? 99.957  80.223  129.209 1.00 69.58  ? 225 TYR A N   1 
ATOM   503   C  CA  . TYR A 1 226 ? 98.616  80.323  129.778 1.00 67.15  ? 225 TYR A CA  1 
ATOM   504   C  C   . TYR A 1 226 ? 98.358  79.062  130.573 1.00 56.89  ? 225 TYR A C   1 
ATOM   505   O  O   . TYR A 1 226 ? 98.278  78.004  130.005 1.00 72.89  ? 225 TYR A O   1 
ATOM   506   C  CB  . TYR A 1 226 ? 97.518  80.550  128.718 1.00 77.96  ? 225 TYR A CB  1 
ATOM   507   C  CG  . TYR A 1 226 ? 96.139  80.938  129.216 1.00 78.75  ? 225 TYR A CG  1 
ATOM   508   C  CD1 . TYR A 1 226 ? 95.415  80.056  129.990 1.00 76.16  ? 225 TYR A CD1 1 
ATOM   509   C  CD2 . TYR A 1 226 ? 95.563  82.158  128.904 1.00 71.98  ? 225 TYR A CD2 1 
ATOM   510   C  CE1 . TYR A 1 226 ? 94.158  80.385  130.436 1.00 103.87 ? 225 TYR A CE1 1 
ATOM   511   C  CE2 . TYR A 1 226 ? 94.307  82.496  129.376 1.00 108.34 ? 225 TYR A CE2 1 
ATOM   512   C  CZ  . TYR A 1 226 ? 93.588  81.606  130.152 1.00 103.53 ? 225 TYR A CZ  1 
ATOM   513   O  OH  . TYR A 1 226 ? 92.344  81.853  130.671 1.00 77.67  ? 225 TYR A OH  1 
ATOM   514   N  N   . ARG A 1 227 ? 98.216  79.189  131.876 1.00 68.33  ? 226 ARG A N   1 
ATOM   515   C  CA  . ARG A 1 227 ? 98.117  78.036  132.731 1.00 85.79  ? 226 ARG A CA  1 
ATOM   516   C  C   . ARG A 1 227 ? 96.707  77.776  133.256 1.00 92.33  ? 226 ARG A C   1 
ATOM   517   O  O   . ARG A 1 227 ? 95.994  78.676  133.719 1.00 103.91 ? 226 ARG A O   1 
ATOM   518   C  CB  . ARG A 1 227 ? 99.003  78.222  133.950 1.00 98.57  ? 226 ARG A CB  1 
ATOM   519   C  CG  . ARG A 1 227 ? 100.408 78.633  133.596 1.00 117.37 ? 226 ARG A CG  1 
ATOM   520   C  CD  . ARG A 1 227 ? 101.168 78.842  134.909 1.00 122.96 ? 226 ARG A CD  1 
ATOM   521   N  NE  . ARG A 1 227 ? 100.801 80.059  135.545 1.00 74.96  ? 226 ARG A NE  1 
ATOM   522   C  CZ  . ARG A 1 227 ? 101.618 80.793  136.226 1.00 106.82 ? 226 ARG A CZ  1 
ATOM   523   N  NH1 . ARG A 1 227 ? 101.143 81.913  136.765 1.00 170.58 ? 226 ARG A NH1 1 
ATOM   524   N  NH2 . ARG A 1 227 ? 102.882 80.398  136.376 1.00 110.90 ? 226 ARG A NH2 1 
ATOM   525   N  N   . ILE A 1 228 ? 96.360  76.485  133.226 1.00 101.93 ? 227 ILE A N   1 
ATOM   526   C  CA  . ILE A 1 228 ? 95.066  76.012  133.647 1.00 90.20  ? 227 ILE A CA  1 
ATOM   527   C  C   . ILE A 1 228 ? 95.295  75.025  134.784 1.00 75.46  ? 227 ILE A C   1 
ATOM   528   O  O   . ILE A 1 228 ? 95.444  73.846  134.566 1.00 110.43 ? 227 ILE A O   1 
ATOM   529   C  CB  . ILE A 1 228 ? 94.348  75.502  132.392 1.00 90.18  ? 227 ILE A CB  1 
ATOM   530   C  CG1 . ILE A 1 228 ? 94.139  76.712  131.472 1.00 95.70  ? 227 ILE A CG1 1 
ATOM   531   C  CG2 . ILE A 1 228 ? 93.063  74.784  132.735 1.00 109.18 ? 227 ILE A CG2 1 
ATOM   532   C  CD1 . ILE A 1 228 ? 93.332  76.472  130.251 1.00 121.05 ? 227 ILE A CD1 1 
ATOM   533   N  N   . GLY A 1 229 ? 95.306  75.537  136.008 1.00 103.24 ? 228 GLY A N   1 
ATOM   534   C  CA  . GLY A 1 229 ? 95.638  74.743  137.176 1.00 160.95 ? 228 GLY A CA  1 
ATOM   535   C  C   . GLY A 1 229 ? 94.592  73.681  137.546 1.00 190.77 ? 228 GLY A C   1 
ATOM   536   O  O   . GLY A 1 229 ? 94.961  72.662  138.145 1.00 264.68 ? 228 GLY A O   1 
ATOM   537   N  N   . ASP A 1 230 ? 93.305  73.915  137.221 1.00 163.45 ? 229 ASP A N   1 
ATOM   538   C  CA  . ASP A 1 230 ? 92.298  72.870  137.364 1.00 225.68 ? 229 ASP A CA  1 
ATOM   539   C  C   . ASP A 1 230 ? 91.254  72.989  136.252 1.00 199.39 ? 229 ASP A C   1 
ATOM   540   O  O   . ASP A 1 230 ? 90.524  73.975  136.188 1.00 149.53 ? 229 ASP A O   1 
ATOM   541   C  CB  . ASP A 1 230 ? 91.663  72.861  138.763 1.00 265.87 ? 229 ASP A CB  1 
ATOM   542   C  CG  . ASP A 1 230 ? 90.802  71.636  139.071 1.00 297.22 ? 229 ASP A CG  1 
ATOM   543   O  OD1 . ASP A 1 230 ? 90.270  71.006  138.125 1.00 317.98 ? 229 ASP A OD1 1 
ATOM   544   O  OD2 . ASP A 1 230 ? 90.672  71.303  140.270 1.00 302.31 ? 229 ASP A OD2 1 
ATOM   545   N  N   . LEU A 1 231 ? 91.205  71.930  135.423 1.00 151.89 ? 230 LEU A N   1 
ATOM   546   C  CA  . LEU A 1 231 ? 90.291  71.795  134.306 1.00 158.04 ? 230 LEU A CA  1 
ATOM   547   C  C   . LEU A 1 231 ? 88.835  71.943  134.728 1.00 190.92 ? 230 LEU A C   1 
ATOM   548   O  O   . LEU A 1 231 ? 88.036  72.375  133.901 1.00 180.95 ? 230 LEU A O   1 
ATOM   549   C  CB  . LEU A 1 231 ? 90.512  70.408  133.722 1.00 166.25 ? 230 LEU A CB  1 
ATOM   550   C  CG  . LEU A 1 231 ? 91.841  70.224  133.009 1.00 237.46 ? 230 LEU A CG  1 
ATOM   551   C  CD1 . LEU A 1 231 ? 92.135  68.736  132.833 1.00 271.01 ? 230 LEU A CD1 1 
ATOM   552   C  CD2 . LEU A 1 231 ? 91.802  70.975  131.685 1.00 243.63 ? 230 LEU A CD2 1 
ATOM   553   N  N   . GLN A 1 232 ? 88.499  71.578  135.983 1.00 173.96 ? 231 GLN A N   1 
ATOM   554   C  CA  . GLN A 1 232 ? 87.124  71.649  136.461 1.00 197.02 ? 231 GLN A CA  1 
ATOM   555   C  C   . GLN A 1 232 ? 86.742  73.097  136.700 1.00 144.21 ? 231 GLN A C   1 
ATOM   556   O  O   . GLN A 1 232 ? 85.686  73.520  136.212 1.00 124.34 ? 231 GLN A O   1 
ATOM   557   C  CB  . GLN A 1 232 ? 86.938  70.785  137.710 1.00 228.01 ? 231 GLN A CB  1 
ATOM   558   C  CG  . GLN A 1 232 ? 87.074  69.294  137.381 1.00 320.97 ? 231 GLN A CG  1 
ATOM   559   C  CD  . GLN A 1 232 ? 87.519  68.474  138.569 1.00 418.83 ? 231 GLN A CD  1 
ATOM   560   O  OE1 . GLN A 1 232 ? 86.860  67.509  138.952 1.00 411.90 ? 231 GLN A OE1 1 
ATOM   561   N  NE2 . GLN A 1 232 ? 88.649  68.845  139.161 1.00 504.58 ? 231 GLN A NE2 1 
ATOM   562   N  N   . ALA A 1 233 ? 87.600  73.825  137.422 1.00 150.99 ? 232 ALA A N   1 
ATOM   563   C  CA  . ALA A 1 233 ? 87.327  75.215  137.762 1.00 184.89 ? 232 ALA A CA  1 
ATOM   564   C  C   . ALA A 1 233 ? 87.274  76.116  136.519 1.00 161.61 ? 232 ALA A C   1 
ATOM   565   O  O   . ALA A 1 233 ? 86.556  77.124  136.522 1.00 160.19 ? 232 ALA A O   1 
ATOM   566   C  CB  . ALA A 1 233 ? 88.347  75.709  138.760 1.00 244.33 ? 232 ALA A CB  1 
ATOM   567   N  N   . PHE A 1 234 ? 88.008  75.761  135.456 1.00 107.54 ? 233 PHE A N   1 
ATOM   568   C  CA  . PHE A 1 234 ? 87.955  76.513  134.212 1.00 119.38 ? 233 PHE A CA  1 
ATOM   569   C  C   . PHE A 1 234 ? 86.624  76.327  133.479 1.00 137.47 ? 233 PHE A C   1 
ATOM   570   O  O   . PHE A 1 234 ? 86.304  77.162  132.630 1.00 116.17 ? 233 PHE A O   1 
ATOM   571   C  CB  . PHE A 1 234 ? 89.153  76.108  133.352 1.00 117.51 ? 233 PHE A CB  1 
ATOM   572   C  CG  . PHE A 1 234 ? 89.412  76.900  132.089 1.00 97.08  ? 233 PHE A CG  1 
ATOM   573   C  CD1 . PHE A 1 234 ? 89.435  78.277  132.057 1.00 137.05 ? 233 PHE A CD1 1 
ATOM   574   C  CD2 . PHE A 1 234 ? 89.657  76.264  130.898 1.00 89.56  ? 233 PHE A CD2 1 
ATOM   575   C  CE1 . PHE A 1 234 ? 89.690  78.968  130.879 1.00 136.78 ? 233 PHE A CE1 1 
ATOM   576   C  CE2 . PHE A 1 234 ? 89.932  76.946  129.711 1.00 90.91  ? 233 PHE A CE2 1 
ATOM   577   C  CZ  . PHE A 1 234 ? 89.941  78.306  129.698 1.00 100.08 ? 233 PHE A CZ  1 
ATOM   578   N  N   . GLN A 1 235 ? 85.854  75.264  133.790 1.00 144.99 ? 234 GLN A N   1 
ATOM   579   C  CA  . GLN A 1 235 ? 84.698  74.875  132.986 1.00 172.95 ? 234 GLN A CA  1 
ATOM   580   C  C   . GLN A 1 235 ? 83.344  74.935  133.710 1.00 239.10 ? 234 GLN A C   1 
ATOM   581   O  O   . GLN A 1 235 ? 82.321  75.204  133.084 1.00 215.69 ? 234 GLN A O   1 
ATOM   582   C  CB  . GLN A 1 235 ? 84.951  73.446  132.518 1.00 165.47 ? 234 GLN A CB  1 
ATOM   583   C  CG  . GLN A 1 235 ? 86.124  73.292  131.548 1.00 163.42 ? 234 GLN A CG  1 
ATOM   584   C  CD  . GLN A 1 235 ? 85.750  73.735  130.153 1.00 203.45 ? 234 GLN A CD  1 
ATOM   585   O  OE1 . GLN A 1 235 ? 84.777  74.457  129.915 1.00 181.44 ? 234 GLN A OE1 1 
ATOM   586   N  NE2 . GLN A 1 235 ? 86.520  73.277  129.185 1.00 226.58 ? 234 GLN A NE2 1 
ATOM   587   N  N   . GLY A 1 236 ? 83.313  74.673  135.024 1.00 309.39 ? 235 GLY A N   1 
ATOM   588   C  CA  . GLY A 1 236 ? 82.093  74.231  135.693 1.00 295.05 ? 235 GLY A CA  1 
ATOM   589   C  C   . GLY A 1 236 ? 81.968  72.709  135.637 1.00 264.29 ? 235 GLY A C   1 
ATOM   590   O  O   . GLY A 1 236 ? 82.473  72.087  134.709 1.00 289.45 ? 235 GLY A O   1 
ATOM   591   N  N   . HIS A 1 237 ? 81.300  72.111  136.638 1.00 286.65 ? 236 HIS A N   1 
ATOM   592   C  CA  . HIS A 1 237 ? 81.369  70.667  136.853 1.00 338.14 ? 236 HIS A CA  1 
ATOM   593   C  C   . HIS A 1 237 ? 80.581  69.898  135.788 1.00 388.37 ? 236 HIS A C   1 
ATOM   594   O  O   . HIS A 1 237 ? 79.731  70.453  135.092 1.00 367.85 ? 236 HIS A O   1 
ATOM   595   C  CB  . HIS A 1 237 ? 80.939  70.316  138.283 1.00 362.97 ? 236 HIS A CB  1 
ATOM   596   C  CG  . HIS A 1 237 ? 81.812  70.979  139.298 1.00 428.75 ? 236 HIS A CG  1 
ATOM   597   N  ND1 . HIS A 1 237 ? 83.126  70.638  139.539 1.00 443.51 ? 236 HIS A ND1 1 
ATOM   598   C  CD2 . HIS A 1 237 ? 81.532  71.991  140.120 1.00 496.90 ? 236 HIS A CD2 1 
ATOM   599   C  CE1 . HIS A 1 237 ? 83.612  71.422  140.489 1.00 479.06 ? 236 HIS A CE1 1 
ATOM   600   N  NE2 . HIS A 1 237 ? 82.660  72.252  140.858 1.00 513.94 ? 236 HIS A NE2 1 
ATOM   601   N  N   . GLY A 1 238 ? 80.898  68.600  135.661 1.00 452.97 ? 237 GLY A N   1 
ATOM   602   C  CA  . GLY A 1 238 ? 80.325  67.733  134.638 1.00 490.63 ? 237 GLY A CA  1 
ATOM   603   C  C   . GLY A 1 238 ? 81.067  67.859  133.308 1.00 439.85 ? 237 GLY A C   1 
ATOM   604   O  O   . GLY A 1 238 ? 81.619  66.874  132.811 1.00 432.77 ? 237 GLY A O   1 
ATOM   605   N  N   . ALA A 1 239 ? 81.073  69.081  132.747 1.00 379.55 ? 238 ALA A N   1 
ATOM   606   C  CA  . ALA A 1 239 ? 81.929  69.439  131.619 1.00 331.89 ? 238 ALA A CA  1 
ATOM   607   C  C   . ALA A 1 239 ? 83.415  69.534  132.006 1.00 338.39 ? 238 ALA A C   1 
ATOM   608   O  O   . ALA A 1 239 ? 84.246  69.788  131.135 1.00 341.15 ? 238 ALA A O   1 
ATOM   609   C  CB  . ALA A 1 239 ? 81.438  70.738  131.008 1.00 254.97 ? 238 ALA A CB  1 
ATOM   610   N  N   . GLY A 1 240 ? 83.772  69.352  133.295 1.00 296.05 ? 239 GLY A N   1 
ATOM   611   C  CA  . GLY A 1 240 ? 85.151  69.393  133.769 1.00 297.23 ? 239 GLY A CA  1 
ATOM   612   C  C   . GLY A 1 240 ? 85.921  68.125  133.400 1.00 240.71 ? 239 GLY A C   1 
ATOM   613   O  O   . GLY A 1 240 ? 86.210  67.318  134.295 1.00 227.95 ? 239 GLY A O   1 
ATOM   614   N  N   . ASN A 1 241 ? 86.246  68.008  132.089 1.00 183.76 ? 240 ASN A N   1 
ATOM   615   C  CA  . ASN A 1 241 ? 87.082  66.948  131.529 1.00 177.40 ? 240 ASN A CA  1 
ATOM   616   C  C   . ASN A 1 241 ? 87.802  67.459  130.278 1.00 151.68 ? 240 ASN A C   1 
ATOM   617   O  O   . ASN A 1 241 ? 87.418  68.488  129.716 1.00 135.43 ? 240 ASN A O   1 
ATOM   618   C  CB  . ASN A 1 241 ? 86.255  65.685  131.242 1.00 243.89 ? 240 ASN A CB  1 
ATOM   619   C  CG  . ASN A 1 241 ? 85.178  65.889  130.193 1.00 273.64 ? 240 ASN A CG  1 
ATOM   620   O  OD1 . ASN A 1 241 ? 85.490  66.187  129.042 1.00 184.66 ? 240 ASN A OD1 1 
ATOM   621   N  ND2 . ASN A 1 241 ? 83.916  65.736  130.570 1.00 350.23 ? 240 ASN A ND2 1 
ATOM   622   N  N   . LEU A 1 242 ? 88.842  66.727  129.838 1.00 164.26 ? 241 LEU A N   1 
ATOM   623   C  CA  . LEU A 1 242 ? 89.707  67.101  128.709 1.00 158.49 ? 241 LEU A CA  1 
ATOM   624   C  C   . LEU A 1 242 ? 88.929  67.306  127.400 1.00 166.19 ? 241 LEU A C   1 
ATOM   625   O  O   . LEU A 1 242 ? 89.279  68.165  126.609 1.00 125.31 ? 241 LEU A O   1 
ATOM   626   C  CB  . LEU A 1 242 ? 90.752  66.002  128.508 1.00 145.72 ? 241 LEU A CB  1 
ATOM   627   C  CG  . LEU A 1 242 ? 91.765  65.826  129.631 1.00 157.76 ? 241 LEU A CG  1 
ATOM   628   C  CD1 . LEU A 1 242 ? 92.406  64.446  129.598 1.00 210.37 ? 241 LEU A CD1 1 
ATOM   629   C  CD2 . LEU A 1 242 ? 92.830  66.872  129.503 1.00 174.69 ? 241 LEU A CD2 1 
ATOM   630   N  N   . ALA A 1 243 ? 87.872  66.523  127.157 1.00 215.10 ? 242 ALA A N   1 
ATOM   631   C  CA  . ALA A 1 243 ? 87.047  66.708  125.968 1.00 252.12 ? 242 ALA A CA  1 
ATOM   632   C  C   . ALA A 1 243 ? 86.249  68.019  126.052 1.00 214.70 ? 242 ALA A C   1 
ATOM   633   O  O   . ALA A 1 243 ? 85.902  68.596  125.017 1.00 198.44 ? 242 ALA A O   1 
ATOM   634   C  CB  . ALA A 1 243 ? 86.153  65.500  125.772 1.00 330.70 ? 242 ALA A CB  1 
ATOM   635   N  N   . GLY A 1 244 ? 85.960  68.496  127.274 1.00 162.74 ? 243 GLY A N   1 
ATOM   636   C  CA  . GLY A 1 244 ? 85.455  69.846  127.482 1.00 243.55 ? 243 GLY A CA  1 
ATOM   637   C  C   . GLY A 1 244 ? 86.457  70.923  127.064 1.00 225.08 ? 243 GLY A C   1 
ATOM   638   O  O   . GLY A 1 244 ? 86.084  71.888  126.379 1.00 162.48 ? 243 GLY A O   1 
ATOM   639   N  N   . LEU A 1 245 ? 87.723  70.755  127.479 1.00 201.26 ? 244 LEU A N   1 
ATOM   640   C  CA  . LEU A 1 245 ? 88.761  71.714  127.125 1.00 206.34 ? 244 LEU A CA  1 
ATOM   641   C  C   . LEU A 1 245 ? 88.957  71.749  125.606 1.00 157.52 ? 244 LEU A C   1 
ATOM   642   O  O   . LEU A 1 245 ? 89.171  72.818  125.059 1.00 125.16 ? 244 LEU A O   1 
ATOM   643   C  CB  . LEU A 1 245 ? 90.060  71.425  127.894 1.00 175.75 ? 244 LEU A CB  1 
ATOM   644   C  CG  . LEU A 1 245 ? 91.304  72.189  127.414 1.00 159.00 ? 244 LEU A CG  1 
ATOM   645   C  CD1 . LEU A 1 245 ? 91.175  73.731  127.484 1.00 192.05 ? 244 LEU A CD1 1 
ATOM   646   C  CD2 . LEU A 1 245 ? 92.480  71.721  128.220 1.00 156.45 ? 244 LEU A CD2 1 
ATOM   647   N  N   . LYS A 1 246 ? 88.878  70.607  124.922 1.00 152.56 ? 245 LYS A N   1 
ATOM   648   C  CA  . LYS A 1 246 ? 88.991  70.573  123.474 1.00 217.66 ? 245 LYS A CA  1 
ATOM   649   C  C   . LYS A 1 246 ? 87.988  71.546  122.827 1.00 203.12 ? 245 LYS A C   1 
ATOM   650   O  O   . LYS A 1 246 ? 88.232  72.019  121.712 1.00 226.89 ? 245 LYS A O   1 
ATOM   651   C  CB  . LYS A 1 246 ? 88.790  69.126  123.002 1.00 234.97 ? 245 LYS A CB  1 
ATOM   652   C  CG  . LYS A 1 246 ? 89.002  68.862  121.516 1.00 241.23 ? 245 LYS A CG  1 
ATOM   653   C  CD  . LYS A 1 246 ? 88.886  67.387  121.151 1.00 263.17 ? 245 LYS A CD  1 
ATOM   654   C  CE  . LYS A 1 246 ? 87.578  66.783  121.628 1.00 322.57 ? 245 LYS A CE  1 
ATOM   655   N  NZ  . LYS A 1 246 ? 87.213  65.540  120.912 1.00 374.50 ? 245 LYS A NZ  1 
ATOM   656   N  N   . GLY A 1 247 ? 86.860  71.839  123.502 1.00 164.72 ? 246 GLY A N   1 
ATOM   657   C  CA  . GLY A 1 247 ? 85.867  72.790  123.014 1.00 239.61 ? 246 GLY A CA  1 
ATOM   658   C  C   . GLY A 1 247 ? 86.297  74.257  123.067 1.00 240.38 ? 246 GLY A C   1 
ATOM   659   O  O   . GLY A 1 247 ? 85.820  75.060  122.256 1.00 309.15 ? 246 GLY A O   1 
ATOM   660   N  N   . ARG A 1 248 ? 87.179  74.611  124.018 1.00 195.44 ? 247 ARG A N   1 
ATOM   661   C  CA  . ARG A 1 248 ? 87.453  76.004  124.356 1.00 178.02 ? 247 ARG A CA  1 
ATOM   662   C  C   . ARG A 1 248 ? 88.559  76.641  123.539 1.00 141.06 ? 247 ARG A C   1 
ATOM   663   O  O   . ARG A 1 248 ? 88.634  77.858  123.570 1.00 102.67 ? 247 ARG A O   1 
ATOM   664   C  CB  . ARG A 1 248 ? 87.901  76.137  125.803 1.00 163.64 ? 247 ARG A CB  1 
ATOM   665   C  CG  . ARG A 1 248 ? 86.779  75.826  126.771 1.00 172.85 ? 247 ARG A CG  1 
ATOM   666   C  CD  . ARG A 1 248 ? 85.661  76.851  126.824 1.00 180.42 ? 247 ARG A CD  1 
ATOM   667   N  NE  . ARG A 1 248 ? 84.819  76.522  127.973 1.00 176.54 ? 247 ARG A NE  1 
ATOM   668   C  CZ  . ARG A 1 248 ? 83.677  77.125  128.284 1.00 180.81 ? 247 ARG A CZ  1 
ATOM   669   N  NH1 . ARG A 1 248 ? 82.968  76.652  129.295 1.00 162.76 ? 247 ARG A NH1 1 
ATOM   670   N  NH2 . ARG A 1 248 ? 83.251  78.170  127.582 1.00 161.23 ? 247 ARG A NH2 1 
ATOM   671   N  N   . LEU A 1 249 ? 89.367  75.851  122.825 1.00 129.78 ? 248 LEU A N   1 
ATOM   672   C  CA  . LEU A 1 249 ? 90.543  76.382  122.164 1.00 123.59 ? 248 LEU A CA  1 
ATOM   673   C  C   . LEU A 1 249 ? 90.238  77.533  121.188 1.00 132.50 ? 248 LEU A C   1 
ATOM   674   O  O   . LEU A 1 249 ? 91.174  78.237  120.838 1.00 124.10 ? 248 LEU A O   1 
ATOM   675   C  CB  . LEU A 1 249 ? 91.264  75.280  121.391 1.00 115.69 ? 248 LEU A CB  1 
ATOM   676   C  CG  . LEU A 1 249 ? 91.675  74.004  122.132 1.00 150.73 ? 248 LEU A CG  1 
ATOM   677   C  CD1 . LEU A 1 249 ? 92.409  73.101  121.170 1.00 234.53 ? 248 LEU A CD1 1 
ATOM   678   C  CD2 . LEU A 1 249 ? 92.563  74.204  123.322 1.00 127.59 ? 248 LEU A CD2 1 
ATOM   679   N  N   . ASP A 1 250 ? 89.000  77.778  120.718 1.00 140.86 ? 249 ASP A N   1 
ATOM   680   C  CA  . ASP A 1 250 ? 88.759  78.940  119.865 1.00 163.41 ? 249 ASP A CA  1 
ATOM   681   C  C   . ASP A 1 250 ? 88.870  80.255  120.645 1.00 154.40 ? 249 ASP A C   1 
ATOM   682   O  O   . ASP A 1 250 ? 89.224  81.316  120.093 1.00 235.07 ? 249 ASP A O   1 
ATOM   683   C  CB  . ASP A 1 250 ? 87.419  78.822  119.132 1.00 271.33 ? 249 ASP A CB  1 
ATOM   684   C  CG  . ASP A 1 250 ? 87.365  79.620  117.836 1.00 389.98 ? 249 ASP A CG  1 
ATOM   685   O  OD1 . ASP A 1 250 ? 88.391  79.661  117.120 1.00 461.74 ? 249 ASP A OD1 1 
ATOM   686   O  OD2 . ASP A 1 250 ? 86.290  80.194  117.545 1.00 442.93 ? 249 ASP A OD2 1 
ATOM   687   N  N   . TYR A 1 251 ? 88.569  80.200  121.947 1.00 166.55 ? 250 TYR A N   1 
ATOM   688   C  CA  . TYR A 1 251 ? 88.816  81.317  122.851 1.00 154.92 ? 250 TYR A CA  1 
ATOM   689   C  C   . TYR A 1 251 ? 90.296  81.561  122.961 1.00 102.75 ? 250 TYR A C   1 
ATOM   690   O  O   . TYR A 1 251 ? 90.726  82.690  122.735 1.00 82.55  ? 250 TYR A O   1 
ATOM   691   C  CB  . TYR A 1 251 ? 88.296  80.973  124.236 1.00 143.75 ? 250 TYR A CB  1 
ATOM   692   C  CG  . TYR A 1 251 ? 88.592  81.980  125.323 1.00 117.42 ? 250 TYR A CG  1 
ATOM   693   C  CD1 . TYR A 1 251 ? 88.362  83.350  125.186 1.00 143.99 ? 250 TYR A CD1 1 
ATOM   694   C  CD2 . TYR A 1 251 ? 89.099  81.518  126.515 1.00 115.65 ? 250 TYR A CD2 1 
ATOM   695   C  CE1 . TYR A 1 251 ? 88.622  84.223  126.234 1.00 168.09 ? 250 TYR A CE1 1 
ATOM   696   C  CE2 . TYR A 1 251 ? 89.368  82.376  127.572 1.00 124.76 ? 250 TYR A CE2 1 
ATOM   697   C  CZ  . TYR A 1 251 ? 89.131  83.735  127.434 1.00 129.81 ? 250 TYR A CZ  1 
ATOM   698   O  OH  . TYR A 1 251 ? 89.416  84.523  128.517 1.00 68.25  ? 250 TYR A OH  1 
ATOM   699   N  N   . LEU A 1 252 ? 91.028  80.483  123.297 1.00 87.45  ? 251 LEU A N   1 
ATOM   700   C  CA  . LEU A 1 252 ? 92.461  80.569  123.472 1.00 87.52  ? 251 LEU A CA  1 
ATOM   701   C  C   . LEU A 1 252 ? 93.095  81.087  122.183 1.00 81.59  ? 251 LEU A C   1 
ATOM   702   O  O   . LEU A 1 252 ? 93.968  81.956  122.247 1.00 138.00 ? 251 LEU A O   1 
ATOM   703   C  CB  . LEU A 1 252 ? 93.033  79.232  123.950 1.00 76.43  ? 251 LEU A CB  1 
ATOM   704   C  CG  . LEU A 1 252 ? 92.555  78.679  125.306 1.00 102.87 ? 251 LEU A CG  1 
ATOM   705   C  CD1 . LEU A 1 252 ? 93.622  77.709  125.801 1.00 125.74 ? 251 LEU A CD1 1 
ATOM   706   C  CD2 . LEU A 1 252 ? 92.259  79.695  126.430 1.00 94.58  ? 251 LEU A CD2 1 
ATOM   707   N  N   . SER A 1 253 ? 92.670  80.602  121.035 1.00 64.66  ? 252 SER A N   1 
ATOM   708   C  CA  . SER A 1 253 ? 93.215  81.096  119.786 1.00 106.34 ? 252 SER A CA  1 
ATOM   709   C  C   . SER A 1 253 ? 92.922  82.597  119.601 1.00 104.84 ? 252 SER A C   1 
ATOM   710   O  O   . SER A 1 253 ? 93.775  83.319  119.060 1.00 198.31 ? 252 SER A O   1 
ATOM   711   C  CB  . SER A 1 253 ? 92.697  80.230  118.669 1.00 192.63 ? 252 SER A CB  1 
ATOM   712   O  OG  . SER A 1 253 ? 93.226  80.622  117.411 1.00 240.16 ? 252 SER A OG  1 
ATOM   713   N  N   . SER A 1 254 ? 91.766  83.088  120.084 1.00 106.19 ? 253 SER A N   1 
ATOM   714   C  CA  . SER A 1 254 ? 91.456  84.529  120.132 1.00 152.87 ? 253 SER A CA  1 
ATOM   715   C  C   . SER A 1 254 ? 92.376  85.340  121.062 1.00 155.27 ? 253 SER A C   1 
ATOM   716   O  O   . SER A 1 254 ? 92.755  86.468  120.755 1.00 138.36 ? 253 SER A O   1 
ATOM   717   C  CB  . SER A 1 254 ? 90.013  84.793  120.493 1.00 153.00 ? 253 SER A CB  1 
ATOM   718   O  OG  . SER A 1 254 ? 89.161  84.094  119.583 1.00 264.89 ? 253 SER A OG  1 
ATOM   719   N  N   . LEU A 1 255 ? 92.770  84.762  122.199 1.00 120.71 ? 254 LEU A N   1 
ATOM   720   C  CA  . LEU A 1 255 ? 93.817  85.331  123.043 1.00 71.25  ? 254 LEU A CA  1 
ATOM   721   C  C   . LEU A 1 255 ? 95.219  85.275  122.452 1.00 75.39  ? 254 LEU A C   1 
ATOM   722   O  O   . LEU A 1 255 ? 96.131  85.889  122.987 1.00 105.86 ? 254 LEU A O   1 
ATOM   723   C  CB  . LEU A 1 255 ? 93.870  84.524  124.332 1.00 67.37  ? 254 LEU A CB  1 
ATOM   724   C  CG  . LEU A 1 255 ? 92.632  84.579  125.221 1.00 88.90  ? 254 LEU A CG  1 
ATOM   725   C  CD1 . LEU A 1 255 ? 92.915  83.925  126.554 1.00 81.34  ? 254 LEU A CD1 1 
ATOM   726   C  CD2 . LEU A 1 255 ? 92.153  85.992  125.436 1.00 90.98  ? 254 LEU A CD2 1 
ATOM   727   N  N   . LYS A 1 256 ? 95.401  84.543  121.364 1.00 124.63 ? 255 LYS A N   1 
ATOM   728   C  CA  . LYS A 1 256 ? 96.667  84.423  120.641 1.00 129.55 ? 255 LYS A CA  1 
ATOM   729   C  C   . LYS A 1 256 ? 97.749  83.815  121.525 1.00 85.17  ? 255 LYS A C   1 
ATOM   730   O  O   . LYS A 1 256 ? 98.930  84.024  121.208 1.00 81.39  ? 255 LYS A O   1 
ATOM   731   C  CB  . LYS A 1 256 ? 97.039  85.756  119.979 1.00 111.06 ? 255 LYS A CB  1 
ATOM   732   C  CG  . LYS A 1 256 ? 95.976  86.340  119.044 1.00 116.81 ? 255 LYS A CG  1 
ATOM   733   C  CD  . LYS A 1 256 ? 96.449  87.509  118.213 1.00 172.49 ? 255 LYS A CD  1 
ATOM   734   C  CE  . LYS A 1 256 ? 95.335  88.042  117.339 1.00 282.62 ? 255 LYS A CE  1 
ATOM   735   N  NZ  . LYS A 1 256 ? 94.150  88.498  118.115 1.00 301.09 ? 255 LYS A NZ  1 
ATOM   736   N  N   . VAL A 1 257 ? 97.311  83.033  122.548 1.00 63.42  ? 256 VAL A N   1 
ATOM   737   C  CA  . VAL A 1 257 ? 98.240  82.334  123.438 1.00 86.75  ? 256 VAL A CA  1 
ATOM   738   C  C   . VAL A 1 257 ? 98.948  81.181  122.742 1.00 62.60  ? 256 VAL A C   1 
ATOM   739   O  O   . VAL A 1 257 ? 98.316  80.232  122.461 1.00 86.60  ? 256 VAL A O   1 
ATOM   740   C  CB  . VAL A 1 257 ? 97.645  81.882  124.780 1.00 88.97  ? 256 VAL A CB  1 
ATOM   741   C  CG1 . VAL A 1 257 ? 97.405  83.140  125.575 1.00 128.35 ? 256 VAL A CG1 1 
ATOM   742   C  CG2 . VAL A 1 257 ? 96.399  81.030  124.714 1.00 88.17  ? 256 VAL A CG2 1 
ATOM   743   N  N   . LYS A 1 258 ? 100.272 81.289  122.498 1.00 80.97  ? 257 LYS A N   1 
ATOM   744   C  CA  . LYS A 1 258 ? 101.132 80.316  121.834 1.00 78.63  ? 257 LYS A CA  1 
ATOM   745   C  C   . LYS A 1 258 ? 101.483 79.199  122.811 1.00 64.06  ? 257 LYS A C   1 
ATOM   746   O  O   . LYS A 1 258 ? 102.602 78.710  122.815 1.00 105.73 ? 257 LYS A O   1 
ATOM   747   C  CB  . LYS A 1 258 ? 102.392 81.021  121.295 1.00 91.15  ? 257 LYS A CB  1 
ATOM   748   C  CG  . LYS A 1 258 ? 102.142 82.195  120.342 1.00 137.24 ? 257 LYS A CG  1 
ATOM   749   C  CD  . LYS A 1 258 ? 101.569 81.810  118.991 1.00 177.88 ? 257 LYS A CD  1 
ATOM   750   C  CE  . LYS A 1 258 ? 101.501 82.989  118.051 1.00 218.77 ? 257 LYS A CE  1 
ATOM   751   N  NZ  . LYS A 1 258 ? 101.266 82.568  116.648 1.00 299.74 ? 257 LYS A NZ  1 
ATOM   752   N  N   . GLY A 1 259 ? 100.542 78.792  123.630 1.00 47.43  ? 258 GLY A N   1 
ATOM   753   C  CA  . GLY A 1 259 ? 100.834 77.813  124.643 1.00 58.40  ? 258 GLY A CA  1 
ATOM   754   C  C   . GLY A 1 259 ? 99.642  77.566  125.586 1.00 72.71  ? 258 GLY A C   1 
ATOM   755   O  O   . GLY A 1 259 ? 98.628  78.296  125.561 1.00 61.11  ? 258 GLY A O   1 
ATOM   756   N  N   . LEU A 1 260 ? 99.817  76.519  126.419 1.00 65.65  ? 259 LEU A N   1 
ATOM   757   C  CA  . LEU A 1 260 ? 98.882  76.033  127.432 1.00 74.00  ? 259 LEU A CA  1 
ATOM   758   C  C   . LEU A 1 260 ? 99.699  75.254  128.433 1.00 77.63  ? 259 LEU A C   1 
ATOM   759   O  O   . LEU A 1 260 ? 100.764 74.736  128.077 1.00 154.16 ? 259 LEU A O   1 
ATOM   760   C  CB  . LEU A 1 260 ? 97.878  75.023  126.856 1.00 97.17  ? 259 LEU A CB  1 
ATOM   761   C  CG  . LEU A 1 260 ? 96.449  75.471  126.747 1.00 102.20 ? 259 LEU A CG  1 
ATOM   762   C  CD1 . LEU A 1 260 ? 95.651  74.381  126.124 1.00 129.84 ? 259 LEU A CD1 1 
ATOM   763   C  CD2 . LEU A 1 260 ? 95.928  75.775  128.118 1.00 121.68 ? 259 LEU A CD2 1 
ATOM   764   N  N   . VAL A 1 261 ? 99.192  75.120  129.646 1.00 72.05  ? 260 VAL A N   1 
ATOM   765   C  CA  . VAL A 1 261 ? 99.844  74.316  130.666 1.00 69.87  ? 260 VAL A CA  1 
ATOM   766   C  C   . VAL A 1 261 ? 98.708  73.640  131.420 1.00 93.56  ? 260 VAL A C   1 
ATOM   767   O  O   . VAL A 1 261 ? 97.988  74.301  132.165 1.00 119.80 ? 260 VAL A O   1 
ATOM   768   C  CB  . VAL A 1 261 ? 100.705 75.204  131.596 1.00 85.47  ? 260 VAL A CB  1 
ATOM   769   C  CG1 . VAL A 1 261 ? 101.264 74.500  132.804 1.00 80.64  ? 260 VAL A CG1 1 
ATOM   770   C  CG2 . VAL A 1 261 ? 101.814 75.933  130.845 1.00 91.78  ? 260 VAL A CG2 1 
ATOM   771   N  N   . LEU A 1 262 ? 98.533  72.326  131.246 1.00 107.37 ? 261 LEU A N   1 
ATOM   772   C  CA  . LEU A 1 262 ? 97.456  71.618  131.939 1.00 99.91  ? 261 LEU A CA  1 
ATOM   773   C  C   . LEU A 1 262 ? 97.965  71.184  133.287 1.00 105.99 ? 261 LEU A C   1 
ATOM   774   O  O   . LEU A 1 262 ? 98.820  70.314  133.354 1.00 73.18  ? 261 LEU A O   1 
ATOM   775   C  CB  . LEU A 1 262 ? 96.987  70.385  131.204 1.00 98.64  ? 261 LEU A CB  1 
ATOM   776   C  CG  . LEU A 1 262 ? 95.928  70.673  130.154 1.00 136.82 ? 261 LEU A CG  1 
ATOM   777   C  CD1 . LEU A 1 262 ? 96.285  71.814  129.180 1.00 119.47 ? 261 LEU A CD1 1 
ATOM   778   C  CD2 . LEU A 1 262 ? 95.734  69.383  129.396 1.00 171.61 ? 261 LEU A CD2 1 
ATOM   779   N  N   . GLY A 1 263 ? 97.426  71.835  134.332 1.00 170.39 ? 262 GLY A N   1 
ATOM   780   C  CA  . GLY A 1 263 ? 97.732  71.494  135.702 1.00 139.20 ? 262 GLY A CA  1 
ATOM   781   C  C   . GLY A 1 263 ? 97.401  70.040  135.936 1.00 116.87 ? 262 GLY A C   1 
ATOM   782   O  O   . GLY A 1 263 ? 96.501  69.513  135.278 1.00 106.32 ? 262 GLY A O   1 
ATOM   783   N  N   . PRO A 1 264 ? 98.134  69.396  136.863 1.00 130.91 ? 263 PRO A N   1 
ATOM   784   C  CA  . PRO A 1 264 ? 98.393  67.963  136.804 1.00 142.38 ? 263 PRO A CA  1 
ATOM   785   C  C   . PRO A 1 264 ? 97.149  67.100  136.674 1.00 163.97 ? 263 PRO A C   1 
ATOM   786   O  O   . PRO A 1 264 ? 96.153  67.285  137.388 1.00 155.04 ? 263 PRO A O   1 
ATOM   787   C  CB  . PRO A 1 264 ? 99.024  67.687  138.151 1.00 152.05 ? 263 PRO A CB  1 
ATOM   788   C  CG  . PRO A 1 264 ? 99.738  68.956  138.473 1.00 160.84 ? 263 PRO A CG  1 
ATOM   789   C  CD  . PRO A 1 264 ? 98.777  70.029  138.014 1.00 137.73 ? 263 PRO A CD  1 
ATOM   790   N  N   . ILE A 1 265 ? 97.248  66.164  135.731 1.00 134.21 ? 264 ILE A N   1 
ATOM   791   C  CA  . ILE A 1 265 ? 96.161  65.253  135.444 1.00 122.60 ? 264 ILE A CA  1 
ATOM   792   C  C   . ILE A 1 265 ? 96.531  63.818  135.774 1.00 110.19 ? 264 ILE A C   1 
ATOM   793   O  O   . ILE A 1 265 ? 95.715  62.923  135.548 1.00 167.57 ? 264 ILE A O   1 
ATOM   794   C  CB  . ILE A 1 265 ? 95.714  65.379  133.970 1.00 145.83 ? 264 ILE A CB  1 
ATOM   795   C  CG1 . ILE A 1 265 ? 96.851  65.122  132.980 1.00 155.22 ? 264 ILE A CG1 1 
ATOM   796   C  CG2 . ILE A 1 265 ? 95.011  66.713  133.709 1.00 136.92 ? 264 ILE A CG2 1 
ATOM   797   C  CD1 . ILE A 1 265 ? 96.358  64.951  131.559 1.00 203.51 ? 264 ILE A CD1 1 
ATOM   798   N  N   . HIS A 1 266 ? 97.722  63.572  136.295 1.00 108.66 ? 265 HIS A N   1 
ATOM   799   C  CA  . HIS A 1 266 ? 98.119  62.200  136.565 1.00 141.04 ? 265 HIS A CA  1 
ATOM   800   C  C   . HIS A 1 266 ? 97.414  61.663  137.819 1.00 153.83 ? 265 HIS A C   1 
ATOM   801   O  O   . HIS A 1 266 ? 96.925  62.439  138.624 1.00 143.64 ? 265 HIS A O   1 
ATOM   802   C  CB  . HIS A 1 266 ? 99.642  62.145  136.589 1.00 163.39 ? 265 HIS A CB  1 
ATOM   803   C  CG  . HIS A 1 266 ? 100.215 62.970  137.669 1.00 149.73 ? 265 HIS A CG  1 
ATOM   804   N  ND1 . HIS A 1 266 ? 100.752 64.215  137.451 1.00 175.75 ? 265 HIS A ND1 1 
ATOM   805   C  CD2 . HIS A 1 266 ? 100.330 62.712  138.977 1.00 152.02 ? 265 HIS A CD2 1 
ATOM   806   C  CE1 . HIS A 1 266 ? 101.172 64.679  138.609 1.00 199.88 ? 265 HIS A CE1 1 
ATOM   807   N  NE2 . HIS A 1 266 ? 100.926 63.787  139.540 1.00 158.41 ? 265 HIS A NE2 1 
ATOM   808   N  N   . LYS A 1 267 ? 97.371  60.322  137.964 1.00 165.59 ? 266 LYS A N   1 
ATOM   809   C  CA  . LYS A 1 267 ? 96.689  59.643  139.065 1.00 181.24 ? 266 LYS A CA  1 
ATOM   810   C  C   . LYS A 1 267 ? 97.470  59.795  140.375 1.00 175.31 ? 266 LYS A C   1 
ATOM   811   O  O   . LYS A 1 267 ? 98.323  58.971  140.722 1.00 189.18 ? 266 LYS A O   1 
ATOM   812   C  CB  . LYS A 1 267 ? 96.456  58.178  138.682 1.00 272.17 ? 266 LYS A CB  1 
ATOM   813   C  CG  . LYS A 1 267 ? 95.729  57.333  139.724 1.00 360.93 ? 266 LYS A CG  1 
ATOM   814   C  CD  . LYS A 1 267 ? 95.547  55.885  139.306 1.00 406.21 ? 266 LYS A CD  1 
ATOM   815   C  CE  . LYS A 1 267 ? 95.122  54.954  140.426 1.00 384.37 ? 266 LYS A CE  1 
ATOM   816   N  NZ  . LYS A 1 267 ? 96.236  54.604  141.345 1.00 365.24 ? 266 LYS A NZ  1 
ATOM   817   N  N   . ASN A 1 268 ? 97.153  60.867  141.110 1.00 166.66 ? 267 ASN A N   1 
ATOM   818   C  CA  . ASN A 1 268 ? 97.728  61.138  142.419 1.00 179.94 ? 267 ASN A CA  1 
ATOM   819   C  C   . ASN A 1 268 ? 96.694  60.806  143.491 1.00 199.29 ? 267 ASN A C   1 
ATOM   820   O  O   . ASN A 1 268 ? 95.552  61.264  143.404 1.00 170.80 ? 267 ASN A O   1 
ATOM   821   C  CB  . ASN A 1 268 ? 98.188  62.600  142.509 1.00 210.80 ? 267 ASN A CB  1 
ATOM   822   C  CG  . ASN A 1 268 ? 98.525  63.083  143.906 1.00 201.66 ? 267 ASN A CG  1 
ATOM   823   O  OD1 . ASN A 1 268 ? 98.097  64.160  144.304 1.00 206.51 ? 267 ASN A OD1 1 
ATOM   824   N  ND2 . ASN A 1 268 ? 99.297  62.323  144.660 1.00 187.17 ? 267 ASN A ND2 1 
ATOM   825   N  N   . GLN A 1 269 ? 97.118  60.019  144.497 1.00 240.31 ? 268 GLN A N   1 
ATOM   826   C  CA  . GLN A 1 269 ? 96.379  59.838  145.740 1.00 248.66 ? 268 GLN A CA  1 
ATOM   827   C  C   . GLN A 1 269 ? 97.086  60.636  146.840 1.00 196.12 ? 268 GLN A C   1 
ATOM   828   O  O   . GLN A 1 269 ? 98.293  60.536  147.016 1.00 159.81 ? 268 GLN A O   1 
ATOM   829   C  CB  . GLN A 1 269 ? 96.240  58.339  146.037 1.00 263.87 ? 268 GLN A CB  1 
ATOM   830   C  CG  . GLN A 1 269 ? 95.811  57.968  147.460 1.00 280.12 ? 268 GLN A CG  1 
ATOM   831   C  CD  . GLN A 1 269 ? 94.502  58.527  147.959 1.00 291.10 ? 268 GLN A CD  1 
ATOM   832   O  OE1 . GLN A 1 269 ? 93.919  59.449  147.392 1.00 313.28 ? 268 GLN A OE1 1 
ATOM   833   N  NE2 . GLN A 1 269 ? 94.028  57.958  149.057 1.00 294.09 ? 268 GLN A NE2 1 
ATOM   834   N  N   . LYS A 1 270 ? 96.329  61.431  147.596 1.00 200.53 ? 269 LYS A N   1 
ATOM   835   C  CA  . LYS A 1 270 ? 96.905  62.447  148.469 1.00 193.51 ? 269 LYS A CA  1 
ATOM   836   C  C   . LYS A 1 270 ? 97.920  61.843  149.454 1.00 155.15 ? 269 LYS A C   1 
ATOM   837   O  O   . LYS A 1 270 ? 97.600  60.941  150.222 1.00 158.70 ? 269 LYS A O   1 
ATOM   838   C  CB  . LYS A 1 270 ? 95.759  63.165  149.189 1.00 230.24 ? 269 LYS A CB  1 
ATOM   839   C  CG  . LYS A 1 270 ? 96.177  64.215  150.203 1.00 220.87 ? 269 LYS A CG  1 
ATOM   840   C  CD  . LYS A 1 270 ? 95.000  64.872  150.885 1.00 226.30 ? 269 LYS A CD  1 
ATOM   841   C  CE  . LYS A 1 270 ? 95.437  65.967  151.834 1.00 272.82 ? 269 LYS A CE  1 
ATOM   842   N  NZ  . LYS A 1 270 ? 96.245  65.443  152.964 1.00 271.16 ? 269 LYS A NZ  1 
ATOM   843   N  N   . ASP A 1 271 ? 99.151  62.369  149.414 1.00 205.30 ? 270 ASP A N   1 
ATOM   844   C  CA  . ASP A 1 271 ? 100.281 62.026  150.283 1.00 243.53 ? 270 ASP A CA  1 
ATOM   845   C  C   . ASP A 1 271 ? 100.684 60.543  150.230 1.00 199.04 ? 270 ASP A C   1 
ATOM   846   O  O   . ASP A 1 271 ? 101.525 60.143  151.041 1.00 186.59 ? 270 ASP A O   1 
ATOM   847   C  CB  . ASP A 1 271 ? 100.045 62.530  151.719 1.00 258.06 ? 270 ASP A CB  1 
ATOM   848   C  CG  . ASP A 1 271 ? 99.713  64.013  151.813 1.00 280.50 ? 270 ASP A CG  1 
ATOM   849   O  OD1 . ASP A 1 271 ? 100.395 64.826  151.131 1.00 343.82 ? 270 ASP A OD1 1 
ATOM   850   O  OD2 . ASP A 1 271 ? 98.767  64.351  152.563 1.00 281.99 ? 270 ASP A OD2 1 
ATOM   851   N  N   . ASP A 1 272 ? 100.140 59.745  149.284 1.00 167.70 ? 271 ASP A N   1 
ATOM   852   C  CA  . ASP A 1 272 ? 100.516 58.344  149.127 1.00 241.11 ? 271 ASP A CA  1 
ATOM   853   C  C   . ASP A 1 272 ? 101.503 58.199  147.959 1.00 240.14 ? 271 ASP A C   1 
ATOM   854   O  O   . ASP A 1 272 ? 101.137 58.288  146.784 1.00 232.65 ? 271 ASP A O   1 
ATOM   855   C  CB  . ASP A 1 272 ? 99.279  57.463  148.957 1.00 290.26 ? 271 ASP A CB  1 
ATOM   856   C  CG  . ASP A 1 272 ? 99.550  55.965  149.026 1.00 331.05 ? 271 ASP A CG  1 
ATOM   857   O  OD1 . ASP A 1 272 ? 100.624 55.524  148.548 1.00 261.99 ? 271 ASP A OD1 1 
ATOM   858   O  OD2 . ASP A 1 272 ? 98.680  55.236  149.544 1.00 380.82 ? 271 ASP A OD2 1 
ATOM   859   N  N   . VAL A 1 273 ? 102.773 57.938  148.310 1.00 213.35 ? 272 VAL A N   1 
ATOM   860   C  CA  . VAL A 1 273 ? 103.878 57.844  147.369 1.00 173.75 ? 272 VAL A CA  1 
ATOM   861   C  C   . VAL A 1 273 ? 103.680 56.644  146.448 1.00 168.99 ? 272 VAL A C   1 
ATOM   862   O  O   . VAL A 1 273 ? 104.071 56.714  145.280 1.00 181.95 ? 272 VAL A O   1 
ATOM   863   C  CB  . VAL A 1 273 ? 105.231 57.742  148.109 1.00 218.24 ? 272 VAL A CB  1 
ATOM   864   C  CG1 . VAL A 1 273 ? 106.412 57.814  147.140 1.00 232.12 ? 272 VAL A CG1 1 
ATOM   865   C  CG2 . VAL A 1 273 ? 105.383 58.795  149.218 1.00 242.51 ? 272 VAL A CG2 1 
ATOM   866   N  N   . ALA A 1 274 ? 103.098 55.554  146.981 1.00 210.76 ? 273 ALA A N   1 
ATOM   867   C  CA  . ALA A 1 274 ? 103.019 54.269  146.292 1.00 301.36 ? 273 ALA A CA  1 
ATOM   868   C  C   . ALA A 1 274 ? 101.795 54.178  145.368 1.00 298.79 ? 273 ALA A C   1 
ATOM   869   O  O   . ALA A 1 274 ? 101.899 53.635  144.265 1.00 265.72 ? 273 ALA A O   1 
ATOM   870   C  CB  . ALA A 1 274 ? 103.027 53.167  147.327 1.00 350.44 ? 273 ALA A CB  1 
ATOM   871   N  N   . GLN A 1 275 ? 100.637 54.697  145.811 1.00 283.37 ? 274 GLN A N   1 
ATOM   872   C  CA  . GLN A 1 275 ? 99.418  54.722  145.005 1.00 317.10 ? 274 GLN A CA  1 
ATOM   873   C  C   . GLN A 1 275 ? 99.443  55.810  143.923 1.00 255.52 ? 274 GLN A C   1 
ATOM   874   O  O   . GLN A 1 275 ? 98.645  55.766  142.990 1.00 184.56 ? 274 GLN A O   1 
ATOM   875   C  CB  . GLN A 1 275 ? 98.195  54.933  145.901 1.00 367.83 ? 274 GLN A CB  1 
ATOM   876   C  CG  . GLN A 1 275 ? 97.856  53.745  146.798 1.00 400.15 ? 274 GLN A CG  1 
ATOM   877   C  CD  . GLN A 1 275 ? 97.242  52.568  146.073 1.00 432.23 ? 274 GLN A CD  1 
ATOM   878   O  OE1 . GLN A 1 275 ? 97.105  52.556  144.850 1.00 436.52 ? 274 GLN A OE1 1 
ATOM   879   N  NE2 . GLN A 1 275 ? 96.861  51.553  146.834 1.00 446.86 ? 274 GLN A NE2 1 
ATOM   880   N  N   . THR A 1 276 ? 100.343 56.799  144.039 1.00 235.86 ? 275 THR A N   1 
ATOM   881   C  CA  . THR A 1 276 ? 100.522 57.827  143.018 1.00 238.90 ? 275 THR A CA  1 
ATOM   882   C  C   . THR A 1 276 ? 101.365 57.335  141.836 1.00 230.11 ? 275 THR A C   1 
ATOM   883   O  O   . THR A 1 276 ? 102.427 56.733  142.017 1.00 232.23 ? 275 THR A O   1 
ATOM   884   C  CB  . THR A 1 276 ? 101.190 59.081  143.588 1.00 239.79 ? 275 THR A CB  1 
ATOM   885   O  OG1 . THR A 1 276 ? 100.277 59.650  144.520 1.00 285.77 ? 275 THR A OG1 1 
ATOM   886   C  CG2 . THR A 1 276 ? 101.529 60.134  142.556 1.00 215.90 ? 275 THR A CG2 1 
ATOM   887   N  N   . ASP A 1 277 ? 100.877 57.640  140.620 1.00 226.49 ? 276 ASP A N   1 
ATOM   888   C  CA  . ASP A 1 277 ? 101.588 57.425  139.367 1.00 217.41 ? 276 ASP A CA  1 
ATOM   889   C  C   . ASP A 1 277 ? 101.572 58.712  138.539 1.00 191.29 ? 276 ASP A C   1 
ATOM   890   O  O   . ASP A 1 277 ? 100.564 59.417  138.543 1.00 181.92 ? 276 ASP A O   1 
ATOM   891   C  CB  . ASP A 1 277 ? 100.950 56.266  138.601 1.00 230.06 ? 276 ASP A CB  1 
ATOM   892   C  CG  . ASP A 1 277 ? 101.593 55.971  137.263 1.00 242.85 ? 276 ASP A CG  1 
ATOM   893   O  OD1 . ASP A 1 277 ? 102.774 56.360  137.072 1.00 232.56 ? 276 ASP A OD1 1 
ATOM   894   O  OD2 . ASP A 1 277 ? 100.906 55.372  136.408 1.00 246.66 ? 276 ASP A OD2 1 
ATOM   895   N  N   . LEU A 1 278 ? 102.680 59.001  137.828 1.00 183.13 ? 277 LEU A N   1 
ATOM   896   C  CA  . LEU A 1 278 ? 102.780 60.176  136.961 1.00 170.23 ? 277 LEU A CA  1 
ATOM   897   C  C   . LEU A 1 278 ? 102.461 59.840  135.512 1.00 156.40 ? 277 LEU A C   1 
ATOM   898   O  O   . LEU A 1 278 ? 102.475 60.754  134.680 1.00 137.10 ? 277 LEU A O   1 
ATOM   899   C  CB  . LEU A 1 278 ? 104.179 60.796  137.034 1.00 186.81 ? 277 LEU A CB  1 
ATOM   900   C  CG  . LEU A 1 278 ? 104.692 61.129  138.437 1.00 226.74 ? 277 LEU A CG  1 
ATOM   901   C  CD1 . LEU A 1 278 ? 106.011 61.877  138.359 1.00 189.74 ? 277 LEU A CD1 1 
ATOM   902   C  CD2 . LEU A 1 278 ? 103.678 61.925  139.239 1.00 205.44 ? 277 LEU A CD2 1 
ATOM   903   N  N   . LEU A 1 279 ? 102.169 58.562  135.214 1.00 162.77 ? 278 LEU A N   1 
ATOM   904   C  CA  . LEU A 1 279 ? 101.981 58.120  133.843 1.00 192.14 ? 278 LEU A CA  1 
ATOM   905   C  C   . LEU A 1 279 ? 100.497 57.859  133.559 1.00 177.20 ? 278 LEU A C   1 
ATOM   906   O  O   . LEU A 1 279 ? 99.971  58.406  132.588 1.00 136.23 ? 278 LEU A O   1 
ATOM   907   C  CB  . LEU A 1 279 ? 102.915 56.932  133.623 1.00 197.58 ? 278 LEU A CB  1 
ATOM   908   C  CG  . LEU A 1 279 ? 103.283 56.699  132.171 1.00 232.87 ? 278 LEU A CG  1 
ATOM   909   C  CD1 . LEU A 1 279 ? 104.633 55.991  132.070 1.00 260.80 ? 278 LEU A CD1 1 
ATOM   910   C  CD2 . LEU A 1 279 ? 102.172 55.910  131.485 1.00 297.54 ? 278 LEU A CD2 1 
ATOM   911   N  N   . GLN A 1 280 ? 99.810  57.057  134.386 1.00 165.18 ? 279 GLN A N   1 
ATOM   912   C  CA  . GLN A 1 280 ? 98.366  56.878  134.252 1.00 190.91 ? 279 GLN A CA  1 
ATOM   913   C  C   . GLN A 1 280 ? 97.629  58.173  134.611 1.00 164.33 ? 279 GLN A C   1 
ATOM   914   O  O   . GLN A 1 280 ? 97.926  58.740  135.674 1.00 155.92 ? 279 GLN A O   1 
ATOM   915   C  CB  . GLN A 1 280 ? 97.907  55.722  135.144 1.00 229.34 ? 279 GLN A CB  1 
ATOM   916   C  CG  . GLN A 1 280 ? 96.396  55.493  135.134 1.00 281.94 ? 279 GLN A CG  1 
ATOM   917   C  CD  . GLN A 1 280 ? 95.994  54.195  135.790 1.00 350.75 ? 279 GLN A CD  1 
ATOM   918   O  OE1 . GLN A 1 280 ? 96.604  53.759  136.765 1.00 390.39 ? 279 GLN A OE1 1 
ATOM   919   N  NE2 . GLN A 1 280 ? 94.957  53.563  135.259 1.00 397.96 ? 279 GLN A NE2 1 
ATOM   920   N  N   . ILE A 1 281 ? 96.676  58.632  133.752 1.00 146.92 ? 280 ILE A N   1 
ATOM   921   C  CA  . ILE A 1 281 ? 95.892  59.845  134.062 1.00 154.07 ? 280 ILE A CA  1 
ATOM   922   C  C   . ILE A 1 281 ? 94.769  59.509  135.047 1.00 155.18 ? 280 ILE A C   1 
ATOM   923   O  O   . ILE A 1 281 ? 94.258  58.385  135.065 1.00 199.57 ? 280 ILE A O   1 
ATOM   924   C  CB  . ILE A 1 281 ? 95.368  60.620  132.821 1.00 143.06 ? 280 ILE A CB  1 
ATOM   925   C  CG1 . ILE A 1 281 ? 94.310  59.890  132.012 1.00 184.09 ? 280 ILE A CG1 1 
ATOM   926   C  CG2 . ILE A 1 281 ? 96.514  61.004  131.917 1.00 202.30 ? 280 ILE A CG2 1 
ATOM   927   C  CD1 . ILE A 1 281 ? 92.921  60.345  132.340 1.00 225.89 ? 280 ILE A CD1 1 
ATOM   928   N  N   . ASP A 1 282 ? 94.404  60.511  135.863 1.00 177.10 ? 281 ASP A N   1 
ATOM   929   C  CA  . ASP A 1 282 ? 93.315  60.431  136.819 1.00 225.56 ? 281 ASP A CA  1 
ATOM   930   C  C   . ASP A 1 282 ? 92.005  60.408  136.041 1.00 210.45 ? 281 ASP A C   1 
ATOM   931   O  O   . ASP A 1 282 ? 91.692  61.419  135.405 1.00 160.61 ? 281 ASP A O   1 
ATOM   932   C  CB  . ASP A 1 282 ? 93.387  61.609  137.802 1.00 261.72 ? 281 ASP A CB  1 
ATOM   933   C  CG  . ASP A 1 282 ? 92.369  61.599  138.932 1.00 226.94 ? 281 ASP A CG  1 
ATOM   934   O  OD1 . ASP A 1 282 ? 91.563  60.684  138.971 1.00 227.17 ? 281 ASP A OD1 1 
ATOM   935   O  OD2 . ASP A 1 282 ? 92.394  62.528  139.758 1.00 250.57 ? 281 ASP A OD2 1 
ATOM   936   N  N   . PRO A 1 283 ? 91.227  59.288  136.076 1.00 231.30 ? 282 PRO A N   1 
ATOM   937   C  CA  . PRO A 1 283 ? 90.123  59.085  135.139 1.00 223.48 ? 282 PRO A CA  1 
ATOM   938   C  C   . PRO A 1 283 ? 88.997  60.119  135.193 1.00 201.76 ? 282 PRO A C   1 
ATOM   939   O  O   . PRO A 1 283 ? 88.264  60.212  134.214 1.00 188.99 ? 282 PRO A O   1 
ATOM   940   C  CB  . PRO A 1 283 ? 89.575  57.687  135.496 1.00 265.81 ? 282 PRO A CB  1 
ATOM   941   C  CG  . PRO A 1 283 ? 90.022  57.435  136.913 1.00 242.49 ? 282 PRO A CG  1 
ATOM   942   C  CD  . PRO A 1 283 ? 91.361  58.136  136.989 1.00 246.50 ? 282 PRO A CD  1 
ATOM   943   N  N   . ASN A 1 284 ? 88.864  60.891  136.291 1.00 185.07 ? 283 ASN A N   1 
ATOM   944   C  CA  . ASN A 1 284 ? 87.910  61.996  136.370 1.00 187.24 ? 283 ASN A CA  1 
ATOM   945   C  C   . ASN A 1 284 ? 88.006  62.942  135.164 1.00 211.29 ? 283 ASN A C   1 
ATOM   946   O  O   . ASN A 1 284 ? 86.982  63.432  134.690 1.00 234.23 ? 283 ASN A O   1 
ATOM   947   C  CB  . ASN A 1 284 ? 88.084  62.763  137.682 1.00 186.78 ? 283 ASN A CB  1 
ATOM   948   C  CG  . ASN A 1 284 ? 87.763  61.923  138.904 1.00 249.92 ? 283 ASN A CG  1 
ATOM   949   O  OD1 . ASN A 1 284 ? 87.377  60.755  138.802 1.00 225.31 ? 283 ASN A OD1 1 
ATOM   950   N  ND2 . ASN A 1 284 ? 87.938  62.511  140.078 1.00 311.50 ? 283 ASN A ND2 1 
ATOM   951   N  N   . PHE A 1 285 ? 89.230  63.180  134.668 1.00 236.34 ? 284 PHE A N   1 
ATOM   952   C  CA  . PHE A 1 285 ? 89.489  64.095  133.562 1.00 225.47 ? 284 PHE A CA  1 
ATOM   953   C  C   . PHE A 1 285 ? 89.253  63.464  132.188 1.00 212.90 ? 284 PHE A C   1 
ATOM   954   O  O   . PHE A 1 285 ? 89.269  64.203  131.209 1.00 166.75 ? 284 PHE A O   1 
ATOM   955   C  CB  . PHE A 1 285 ? 90.931  64.613  133.634 1.00 227.07 ? 284 PHE A CB  1 
ATOM   956   C  CG  . PHE A 1 285 ? 91.275  65.313  134.926 1.00 211.73 ? 284 PHE A CG  1 
ATOM   957   C  CD1 . PHE A 1 285 ? 90.507  66.383  135.371 1.00 201.77 ? 284 PHE A CD1 1 
ATOM   958   C  CD2 . PHE A 1 285 ? 92.352  64.902  135.708 1.00 197.61 ? 284 PHE A CD2 1 
ATOM   959   C  CE1 . PHE A 1 285 ? 90.812  67.022  136.566 1.00 229.99 ? 284 PHE A CE1 1 
ATOM   960   C  CE2 . PHE A 1 285 ? 92.656  65.547  136.902 1.00 195.24 ? 284 PHE A CE2 1 
ATOM   961   C  CZ  . PHE A 1 285 ? 91.886  66.607  137.330 1.00 209.37 ? 284 PHE A CZ  1 
ATOM   962   N  N   . GLY A 1 286 ? 89.050  62.138  132.105 1.00 227.66 ? 285 GLY A N   1 
ATOM   963   C  CA  . GLY A 1 286 ? 88.776  61.454  130.846 1.00 234.23 ? 285 GLY A CA  1 
ATOM   964   C  C   . GLY A 1 286 ? 89.624  60.190  130.685 1.00 247.19 ? 285 GLY A C   1 
ATOM   965   O  O   . GLY A 1 286 ? 89.637  59.336  131.566 1.00 249.99 ? 285 GLY A O   1 
ATOM   966   N  N   . SER A 1 287 ? 90.332  60.085  129.547 1.00 229.98 ? 286 SER A N   1 
ATOM   967   C  CA  . SER A 1 287 ? 91.155  58.948  129.142 1.00 207.47 ? 286 SER A CA  1 
ATOM   968   C  C   . SER A 1 287 ? 92.334  59.451  128.319 1.00 189.63 ? 286 SER A C   1 
ATOM   969   O  O   . SER A 1 287 ? 92.275  60.572  127.805 1.00 185.96 ? 286 SER A O   1 
ATOM   970   C  CB  . SER A 1 287 ? 90.348  58.011  128.306 1.00 269.94 ? 286 SER A CB  1 
ATOM   971   O  OG  . SER A 1 287 ? 89.943  58.663  127.096 1.00 321.78 ? 286 SER A OG  1 
ATOM   972   N  N   . LYS A 1 288 ? 93.398  58.649  128.149 1.00 199.25 ? 287 LYS A N   1 
ATOM   973   C  CA  . LYS A 1 288 ? 94.467  59.073  127.242 1.00 232.95 ? 287 LYS A CA  1 
ATOM   974   C  C   . LYS A 1 288 ? 93.924  59.308  125.817 1.00 184.41 ? 287 LYS A C   1 
ATOM   975   O  O   . LYS A 1 288 ? 94.426  60.166  125.093 1.00 167.38 ? 287 LYS A O   1 
ATOM   976   C  CB  . LYS A 1 288 ? 95.651  58.097  127.265 1.00 226.80 ? 287 LYS A CB  1 
ATOM   977   C  CG  . LYS A 1 288 ? 96.722  58.430  126.230 1.00 210.89 ? 287 LYS A CG  1 
ATOM   978   C  CD  . LYS A 1 288 ? 98.148  58.095  126.625 1.00 230.99 ? 287 LYS A CD  1 
ATOM   979   C  CE  . LYS A 1 288 ? 99.049  57.822  125.432 1.00 267.48 ? 287 LYS A CE  1 
ATOM   980   N  NZ  . LYS A 1 288 ? 98.964  58.832  124.354 1.00 268.60 ? 287 LYS A NZ  1 
ATOM   981   N  N   . GLU A 1 289 ? 92.884  58.570  125.425 1.00 191.38 ? 288 GLU A N   1 
ATOM   982   C  CA  . GLU A 1 289 ? 92.204  58.766  124.151 1.00 234.83 ? 288 GLU A CA  1 
ATOM   983   C  C   . GLU A 1 289 ? 91.549  60.152  124.062 1.00 209.18 ? 288 GLU A C   1 
ATOM   984   O  O   . GLU A 1 289 ? 91.510  60.719  122.971 1.00 217.91 ? 288 GLU A O   1 
ATOM   985   C  CB  . GLU A 1 289 ? 91.202  57.627  123.938 1.00 338.83 ? 288 GLU A CB  1 
ATOM   986   C  CG  . GLU A 1 289 ? 91.873  56.282  123.644 1.00 429.62 ? 288 GLU A CG  1 
ATOM   987   C  CD  . GLU A 1 289 ? 92.645  55.610  124.774 1.00 471.76 ? 288 GLU A CD  1 
ATOM   988   O  OE1 . GLU A 1 289 ? 92.336  55.889  125.958 1.00 492.79 ? 288 GLU A OE1 1 
ATOM   989   O  OE2 . GLU A 1 289 ? 93.564  54.815  124.474 1.00 450.66 ? 288 GLU A OE2 1 
ATOM   990   N  N   . ASP A 1 290 ? 91.049  60.711  125.175 1.00 186.76 ? 289 ASP A N   1 
ATOM   991   C  CA  . ASP A 1 290 ? 90.637  62.110  125.199 1.00 214.47 ? 289 ASP A CA  1 
ATOM   992   C  C   . ASP A 1 290 ? 91.846  63.042  125.105 1.00 201.28 ? 289 ASP A C   1 
ATOM   993   O  O   . ASP A 1 290 ? 91.833  64.027  124.354 1.00 154.98 ? 289 ASP A O   1 
ATOM   994   C  CB  . ASP A 1 290 ? 89.843  62.469  126.461 1.00 213.22 ? 289 ASP A CB  1 
ATOM   995   C  CG  . ASP A 1 290 ? 88.609  61.608  126.614 1.00 268.53 ? 289 ASP A CG  1 
ATOM   996   O  OD1 . ASP A 1 290 ? 87.736  61.690  125.738 1.00 365.75 ? 289 ASP A OD1 1 
ATOM   997   O  OD2 . ASP A 1 290 ? 88.546  60.856  127.590 1.00 298.77 ? 289 ASP A OD2 1 
ATOM   998   N  N   . PHE A 1 291 ? 92.887  62.737  125.890 1.00 172.85 ? 290 PHE A N   1 
ATOM   999   C  CA  . PHE A 1 291 ? 94.058  63.588  125.971 1.00 166.22 ? 290 PHE A CA  1 
ATOM   1000  C  C   . PHE A 1 291 ? 94.641  63.786  124.574 1.00 154.15 ? 290 PHE A C   1 
ATOM   1001  O  O   . PHE A 1 291 ? 94.934  64.904  124.171 1.00 147.64 ? 290 PHE A O   1 
ATOM   1002  C  CB  . PHE A 1 291 ? 95.076  63.008  126.972 1.00 178.67 ? 290 PHE A CB  1 
ATOM   1003  C  CG  . PHE A 1 291 ? 96.224  63.958  127.215 1.00 181.86 ? 290 PHE A CG  1 
ATOM   1004  C  CD1 . PHE A 1 291 ? 96.073  65.083  128.012 1.00 217.71 ? 290 PHE A CD1 1 
ATOM   1005  C  CD2 . PHE A 1 291 ? 97.448  63.758  126.607 1.00 168.46 ? 290 PHE A CD2 1 
ATOM   1006  C  CE1 . PHE A 1 291 ? 97.125  65.966  128.206 1.00 214.53 ? 290 PHE A CE1 1 
ATOM   1007  C  CE2 . PHE A 1 291 ? 98.497  64.641  126.808 1.00 186.28 ? 290 PHE A CE2 1 
ATOM   1008  C  CZ  . PHE A 1 291 ? 98.337  65.747  127.603 1.00 216.99 ? 290 PHE A CZ  1 
ATOM   1009  N  N   . ASP A 1 292 ? 94.820  62.685  123.843 1.00 162.88 ? 291 ASP A N   1 
ATOM   1010  C  CA  . ASP A 1 292 ? 95.358  62.729  122.494 1.00 180.65 ? 291 ASP A CA  1 
ATOM   1011  C  C   . ASP A 1 292 ? 94.420  63.489  121.559 1.00 176.88 ? 291 ASP A C   1 
ATOM   1012  O  O   . ASP A 1 292 ? 94.897  64.175  120.657 1.00 226.87 ? 291 ASP A O   1 
ATOM   1013  C  CB  . ASP A 1 292 ? 95.649  61.309  121.995 1.00 230.80 ? 291 ASP A CB  1 
ATOM   1014  C  CG  . ASP A 1 292 ? 96.744  60.584  122.764 1.00 251.85 ? 291 ASP A CG  1 
ATOM   1015  O  OD1 . ASP A 1 292 ? 97.577  61.264  123.388 1.00 228.57 ? 291 ASP A OD1 1 
ATOM   1016  O  OD2 . ASP A 1 292 ? 96.757  59.333  122.745 1.00 303.30 ? 291 ASP A OD2 1 
ATOM   1017  N  N   . SER A 1 293 ? 93.104  63.375  121.766 1.00 161.25 ? 292 SER A N   1 
ATOM   1018  C  CA  . SER A 1 293 ? 92.131  64.048  120.920 1.00 213.55 ? 292 SER A CA  1 
ATOM   1019  C  C   . SER A 1 293 ? 92.273  65.555  121.056 1.00 185.90 ? 292 SER A C   1 
ATOM   1020  O  O   . SER A 1 293 ? 92.251  66.256  120.038 1.00 142.11 ? 292 SER A O   1 
ATOM   1021  C  CB  . SER A 1 293 ? 90.727  63.575  121.247 1.00 279.61 ? 292 SER A CB  1 
ATOM   1022  O  OG  . SER A 1 293 ? 89.771  64.120  120.353 1.00 339.32 ? 292 SER A OG  1 
ATOM   1023  N  N   . LEU A 1 294 ? 92.403  66.014  122.322 1.00 212.66 ? 293 LEU A N   1 
ATOM   1024  C  CA  . LEU A 1 294 ? 92.751  67.393  122.662 1.00 224.36 ? 293 LEU A CA  1 
ATOM   1025  C  C   . LEU A 1 294 ? 94.067  67.786  122.000 1.00 147.88 ? 293 LEU A C   1 
ATOM   1026  O  O   . LEU A 1 294 ? 94.138  68.747  121.239 1.00 99.61  ? 293 LEU A O   1 
ATOM   1027  C  CB  . LEU A 1 294 ? 92.890  67.571  124.184 1.00 164.74 ? 293 LEU A CB  1 
ATOM   1028  C  CG  . LEU A 1 294 ? 93.678  68.806  124.651 1.00 139.22 ? 293 LEU A CG  1 
ATOM   1029  C  CD1 . LEU A 1 294 ? 93.049  70.148  124.190 1.00 125.17 ? 293 LEU A CD1 1 
ATOM   1030  C  CD2 . LEU A 1 294 ? 93.824  68.710  126.146 1.00 167.60 ? 293 LEU A CD2 1 
ATOM   1031  N  N   . LEU A 1 295 ? 95.100  67.025  122.317 1.00 124.71 ? 294 LEU A N   1 
ATOM   1032  C  CA  . LEU A 1 295 ? 96.453  67.403  121.974 1.00 129.95 ? 294 LEU A CA  1 
ATOM   1033  C  C   . LEU A 1 295 ? 96.606  67.555  120.449 1.00 136.12 ? 294 LEU A C   1 
ATOM   1034  O  O   . LEU A 1 295 ? 97.269  68.483  119.989 1.00 127.11 ? 294 LEU A O   1 
ATOM   1035  C  CB  . LEU A 1 295 ? 97.337  66.356  122.656 1.00 122.61 ? 294 LEU A CB  1 
ATOM   1036  C  CG  . LEU A 1 295 ? 98.829  66.460  122.387 1.00 174.14 ? 294 LEU A CG  1 
ATOM   1037  C  CD1 . LEU A 1 295 ? 99.388  67.829  122.752 1.00 221.22 ? 294 LEU A CD1 1 
ATOM   1038  C  CD2 . LEU A 1 295 ? 99.545  65.377  123.156 1.00 176.09 ? 294 LEU A CD2 1 
ATOM   1039  N  N   . GLN A 1 296 ? 95.980  66.660  119.671 1.00 202.94 ? 295 GLN A N   1 
ATOM   1040  C  CA  . GLN A 1 296 ? 95.934  66.751  118.214 1.00 224.31 ? 295 GLN A CA  1 
ATOM   1041  C  C   . GLN A 1 296 ? 95.159  67.994  117.755 1.00 172.76 ? 295 GLN A C   1 
ATOM   1042  O  O   . GLN A 1 296 ? 95.545  68.611  116.761 1.00 213.94 ? 295 GLN A O   1 
ATOM   1043  C  CB  . GLN A 1 296 ? 95.336  65.457  117.653 1.00 247.08 ? 295 GLN A CB  1 
ATOM   1044  C  CG  . GLN A 1 296 ? 95.394  65.332  116.140 1.00 339.53 ? 295 GLN A CG  1 
ATOM   1045  C  CD  . GLN A 1 296 ? 94.923  63.976  115.659 1.00 410.18 ? 295 GLN A CD  1 
ATOM   1046  O  OE1 . GLN A 1 296 ? 94.350  63.189  116.415 1.00 368.93 ? 295 GLN A OE1 1 
ATOM   1047  N  NE2 . GLN A 1 296 ? 95.157  63.690  114.383 1.00 449.12 ? 295 GLN A NE2 1 
ATOM   1048  N  N   . SER A 1 297 ? 94.076  68.362  118.456 1.00 130.89 ? 296 SER A N   1 
ATOM   1049  C  CA  . SER A 1 297 ? 93.325  69.578  118.149 1.00 174.86 ? 296 SER A CA  1 
ATOM   1050  C  C   . SER A 1 297 ? 94.161  70.819  118.425 1.00 175.09 ? 296 SER A C   1 
ATOM   1051  O  O   . SER A 1 297 ? 94.142  71.773  117.650 1.00 188.08 ? 296 SER A O   1 
ATOM   1052  C  CB  . SER A 1 297 ? 92.016  69.663  118.907 1.00 191.20 ? 296 SER A CB  1 
ATOM   1053  O  OG  . SER A 1 297 ? 91.241  68.494  118.699 1.00 292.38 ? 296 SER A OG  1 
ATOM   1054  N  N   . ALA A 1 298 ? 94.887  70.792  119.542 1.00 155.38 ? 297 ALA A N   1 
ATOM   1055  C  CA  . ALA A 1 298 ? 95.721  71.912  119.934 1.00 151.33 ? 297 ALA A CA  1 
ATOM   1056  C  C   . ALA A 1 298 ? 96.826  72.122  118.890 1.00 155.10 ? 297 ALA A C   1 
ATOM   1057  O  O   . ALA A 1 298 ? 97.032  73.255  118.465 1.00 168.81 ? 297 ALA A O   1 
ATOM   1058  C  CB  . ALA A 1 298 ? 96.212  71.657  121.334 1.00 158.54 ? 297 ALA A CB  1 
ATOM   1059  N  N   . LYS A 1 299 ? 97.511  71.045  118.451 1.00 187.01 ? 298 LYS A N   1 
ATOM   1060  C  CA  . LYS A 1 299 ? 98.493  71.107  117.361 1.00 188.36 ? 298 LYS A CA  1 
ATOM   1061  C  C   . LYS A 1 299 ? 97.863  71.728  116.115 1.00 170.87 ? 298 LYS A C   1 
ATOM   1062  O  O   . LYS A 1 299 ? 98.448  72.649  115.543 1.00 193.41 ? 298 LYS A O   1 
ATOM   1063  C  CB  . LYS A 1 299 ? 99.111  69.738  117.017 1.00 201.72 ? 298 LYS A CB  1 
ATOM   1064  C  CG  . LYS A 1 299 ? 100.404 69.410  117.753 1.00 276.40 ? 298 LYS A CG  1 
ATOM   1065  C  CD  . LYS A 1 299 ? 100.254 69.192  119.260 1.00 363.49 ? 298 LYS A CD  1 
ATOM   1066  C  CE  . LYS A 1 299 ? 101.447 69.626  120.088 1.00 427.47 ? 298 LYS A CE  1 
ATOM   1067  N  NZ  . LYS A 1 299 ? 102.661 68.797  119.882 1.00 460.68 ? 298 LYS A NZ  1 
ATOM   1068  N  N   . LYS A 1 300 ? 96.681  71.230  115.719 1.00 207.74 ? 299 LYS A N   1 
ATOM   1069  C  CA  . LYS A 1 300 ? 95.919  71.739  114.582 1.00 260.53 ? 299 LYS A CA  1 
ATOM   1070  C  C   . LYS A 1 300 ? 95.637  73.247  114.728 1.00 213.61 ? 299 LYS A C   1 
ATOM   1071  O  O   . LYS A 1 300 ? 95.653  73.954  113.713 1.00 244.57 ? 299 LYS A O   1 
ATOM   1072  C  CB  . LYS A 1 300 ? 94.662  70.868  114.392 1.00 295.19 ? 299 LYS A CB  1 
ATOM   1073  C  CG  . LYS A 1 300 ? 93.542  71.407  113.508 1.00 359.63 ? 299 LYS A CG  1 
ATOM   1074  C  CD  . LYS A 1 300 ? 93.905  71.623  112.055 1.00 393.17 ? 299 LYS A CD  1 
ATOM   1075  C  CE  . LYS A 1 300 ? 92.765  72.247  111.275 1.00 376.93 ? 299 LYS A CE  1 
ATOM   1076  N  NZ  . LYS A 1 300 ? 93.134  72.551  109.872 1.00 351.86 ? 299 LYS A NZ  1 
ATOM   1077  N  N   . LYS A 1 301 ? 95.383  73.743  115.959 1.00 147.35 ? 300 LYS A N   1 
ATOM   1078  C  CA  . LYS A 1 301 ? 95.069  75.156  116.187 1.00 195.20 ? 300 LYS A CA  1 
ATOM   1079  C  C   . LYS A 1 301 ? 96.280  76.023  116.630 1.00 202.04 ? 300 LYS A C   1 
ATOM   1080  O  O   . LYS A 1 301 ? 96.092  77.191  116.976 1.00 144.66 ? 300 LYS A O   1 
ATOM   1081  C  CB  . LYS A 1 301 ? 93.871  75.226  117.147 1.00 185.10 ? 300 LYS A CB  1 
ATOM   1082  C  CG  . LYS A 1 301 ? 92.850  76.265  116.710 1.00 230.24 ? 300 LYS A CG  1 
ATOM   1083  C  CD  . LYS A 1 301 ? 91.671  76.447  117.632 1.00 222.33 ? 300 LYS A CD  1 
ATOM   1084  C  CE  . LYS A 1 301 ? 90.467  77.109  116.984 1.00 276.38 ? 300 LYS A CE  1 
ATOM   1085  N  NZ  . LYS A 1 301 ? 90.784  78.401  116.319 1.00 294.65 ? 300 LYS A NZ  1 
ATOM   1086  N  N   . SER A 1 302 ? 97.522  75.483  116.600 1.00 199.80 ? 301 SER A N   1 
ATOM   1087  C  CA  . SER A 1 302 ? 98.800  76.171  116.861 1.00 161.10 ? 301 SER A CA  1 
ATOM   1088  C  C   . SER A 1 302 ? 99.038  76.580  118.336 1.00 133.49 ? 301 SER A C   1 
ATOM   1089  O  O   . SER A 1 302 ? 99.891  77.396  118.678 1.00 125.51 ? 301 SER A O   1 
ATOM   1090  C  CB  . SER A 1 302 ? 98.995  77.323  115.903 1.00 201.60 ? 301 SER A CB  1 
ATOM   1091  O  OG  . SER A 1 302 ? 98.940  76.855  114.567 1.00 235.48 ? 301 SER A OG  1 
ATOM   1092  N  N   . ILE A 1 303 ? 98.320  75.960  119.261 1.00 119.50 ? 302 ILE A N   1 
ATOM   1093  C  CA  . ILE A 1 303 ? 98.550  76.043  120.694 1.00 81.98  ? 302 ILE A CA  1 
ATOM   1094  C  C   . ILE A 1 303 ? 99.422  74.865  121.140 1.00 83.79  ? 302 ILE A C   1 
ATOM   1095  O  O   . ILE A 1 303 ? 98.942  73.710  121.209 1.00 88.67  ? 302 ILE A O   1 
ATOM   1096  C  CB  . ILE A 1 303 ? 97.119  76.003  121.301 1.00 98.84  ? 302 ILE A CB  1 
ATOM   1097  C  CG1 . ILE A 1 303 ? 96.404  77.286  120.790 1.00 101.45 ? 302 ILE A CG1 1 
ATOM   1098  C  CG2 . ILE A 1 303 ? 97.055  75.669  122.844 1.00 78.90  ? 302 ILE A CG2 1 
ATOM   1099  C  CD1 . ILE A 1 303 ? 95.096  77.627  121.418 1.00 137.14 ? 302 ILE A CD1 1 
ATOM   1100  N  N   . ARG A 1 304 ? 100.696 75.102  121.426 1.00 90.57  ? 303 ARG A N   1 
ATOM   1101  C  CA  . ARG A 1 304 ? 101.495 73.989  121.957 1.00 125.48 ? 303 ARG A CA  1 
ATOM   1102  C  C   . ARG A 1 304 ? 100.988 73.662  123.364 1.00 80.90  ? 303 ARG A C   1 
ATOM   1103  O  O   . ARG A 1 304 ? 100.568 74.578  124.065 1.00 98.32  ? 303 ARG A O   1 
ATOM   1104  C  CB  . ARG A 1 304 ? 103.009 74.328  121.961 1.00 166.97 ? 303 ARG A CB  1 
ATOM   1105  C  CG  . ARG A 1 304 ? 103.750 74.145  120.628 1.00 112.86 ? 303 ARG A CG  1 
ATOM   1106  C  CD  . ARG A 1 304 ? 103.356 75.242  119.663 1.00 140.41 ? 303 ARG A CD  1 
ATOM   1107  N  NE  . ARG A 1 304 ? 104.286 75.258  118.545 1.00 186.31 ? 303 ARG A NE  1 
ATOM   1108  C  CZ  . ARG A 1 304 ? 104.343 76.235  117.640 1.00 276.31 ? 303 ARG A CZ  1 
ATOM   1109  N  NH1 . ARG A 1 304 ? 105.238 76.192  116.667 1.00 339.33 ? 303 ARG A NH1 1 
ATOM   1110  N  NH2 . ARG A 1 304 ? 103.509 77.260  117.714 1.00 260.73 ? 303 ARG A NH2 1 
ATOM   1111  N  N   . VAL A 1 305 ? 101.061 72.414  123.817 1.00 72.42  ? 304 VAL A N   1 
ATOM   1112  C  CA  . VAL A 1 305 ? 100.587 72.064  125.151 1.00 93.05  ? 304 VAL A CA  1 
ATOM   1113  C  C   . VAL A 1 305 ? 101.661 71.462  126.072 1.00 80.35  ? 304 VAL A C   1 
ATOM   1114  O  O   . VAL A 1 305 ? 102.190 70.411  125.789 1.00 139.12 ? 304 VAL A O   1 
ATOM   1115  C  CB  . VAL A 1 305 ? 99.436  71.059  125.000 1.00 92.66  ? 304 VAL A CB  1 
ATOM   1116  C  CG1 . VAL A 1 305 ? 98.990  70.400  126.342 1.00 64.16  ? 304 VAL A CG1 1 
ATOM   1117  C  CG2 . VAL A 1 305 ? 98.326  71.754  124.219 1.00 92.22  ? 304 VAL A CG2 1 
ATOM   1118  N  N   . ILE A 1 306 ? 101.916 72.087  127.195 1.00 69.96  ? 305 ILE A N   1 
ATOM   1119  C  CA  . ILE A 1 306 ? 102.687 71.558  128.299 1.00 73.94  ? 305 ILE A CA  1 
ATOM   1120  C  C   . ILE A 1 306 ? 101.817 70.882  129.373 1.00 84.81  ? 305 ILE A C   1 
ATOM   1121  O  O   . ILE A 1 306 ? 100.728 71.274  129.715 1.00 80.78  ? 305 ILE A O   1 
ATOM   1122  C  CB  . ILE A 1 306 ? 103.384 72.751  128.935 1.00 82.31  ? 305 ILE A CB  1 
ATOM   1123  C  CG1 . ILE A 1 306 ? 104.355 73.391  127.952 1.00 98.59  ? 305 ILE A CG1 1 
ATOM   1124  C  CG2 . ILE A 1 306 ? 104.018 72.431  130.268 1.00 79.53  ? 305 ILE A CG2 1 
ATOM   1125  C  CD1 . ILE A 1 306 ? 104.461 74.915  128.202 1.00 153.17 ? 305 ILE A CD1 1 
ATOM   1126  N  N   . LEU A 1 307 ? 102.327 69.838  129.973 1.00 88.27  ? 306 LEU A N   1 
ATOM   1127  C  CA  . LEU A 1 307 ? 101.644 69.106  131.014 1.00 93.97  ? 306 LEU A CA  1 
ATOM   1128  C  C   . LEU A 1 307 ? 102.405 69.332  132.317 1.00 90.16  ? 306 LEU A C   1 
ATOM   1129  O  O   . LEU A 1 307 ? 103.631 69.335  132.350 1.00 89.51  ? 306 LEU A O   1 
ATOM   1130  C  CB  . LEU A 1 307 ? 101.660 67.626  130.590 1.00 127.41 ? 306 LEU A CB  1 
ATOM   1131  C  CG  . LEU A 1 307 ? 101.447 66.561  131.660 1.00 137.30 ? 306 LEU A CG  1 
ATOM   1132  C  CD1 . LEU A 1 307 ? 100.009 66.540  132.095 1.00 191.73 ? 306 LEU A CD1 1 
ATOM   1133  C  CD2 . LEU A 1 307 ? 101.862 65.201  131.156 1.00 130.61 ? 306 LEU A CD2 1 
ATOM   1134  N  N   . ASP A 1 308 ? 101.676 69.486  133.421 1.00 99.11  ? 307 ASP A N   1 
ATOM   1135  C  CA  . ASP A 1 308 ? 102.298 69.731  134.720 1.00 111.89 ? 307 ASP A CA  1 
ATOM   1136  C  C   . ASP A 1 308 ? 102.500 68.430  135.481 1.00 121.93 ? 307 ASP A C   1 
ATOM   1137  O  O   . ASP A 1 308 ? 101.540 67.729  135.754 1.00 117.59 ? 307 ASP A O   1 
ATOM   1138  C  CB  . ASP A 1 308 ? 101.428 70.681  135.518 1.00 126.75 ? 307 ASP A CB  1 
ATOM   1139  C  CG  . ASP A 1 308 ? 102.059 71.196  136.807 1.00 155.24 ? 307 ASP A CG  1 
ATOM   1140  O  OD1 . ASP A 1 308 ? 102.929 70.517  137.374 1.00 114.39 ? 307 ASP A OD1 1 
ATOM   1141  O  OD2 . ASP A 1 308 ? 101.641 72.287  137.252 1.00 250.69 ? 307 ASP A OD2 1 
ATOM   1142  N  N   . LEU A 1 309 ? 103.745 68.102  135.841 1.00 120.08 ? 308 LEU A N   1 
ATOM   1143  C  CA  . LEU A 1 309 ? 104.041 66.801  136.425 1.00 115.12 ? 308 LEU A CA  1 
ATOM   1144  C  C   . LEU A 1 309 ? 104.322 66.849  137.926 1.00 116.88 ? 308 LEU A C   1 
ATOM   1145  O  O   . LEU A 1 309 ? 104.821 65.871  138.473 1.00 127.52 ? 308 LEU A O   1 
ATOM   1146  C  CB  . LEU A 1 309 ? 105.261 66.250  135.695 1.00 124.66 ? 308 LEU A CB  1 
ATOM   1147  C  CG  . LEU A 1 309 ? 105.051 65.893  134.237 1.00 115.15 ? 308 LEU A CG  1 
ATOM   1148  C  CD1 . LEU A 1 309 ? 106.379 65.480  133.674 1.00 144.61 ? 308 LEU A CD1 1 
ATOM   1149  C  CD2 . LEU A 1 309 ? 104.092 64.741  134.150 1.00 164.43 ? 308 LEU A CD2 1 
ATOM   1150  N  N   . THR A 1 310 ? 104.011 67.949  138.616 1.00 128.80 ? 309 THR A N   1 
ATOM   1151  C  CA  . THR A 1 310 ? 104.360 68.039  140.027 1.00 125.63 ? 309 THR A CA  1 
ATOM   1152  C  C   . THR A 1 310 ? 103.632 66.907  140.757 1.00 130.66 ? 309 THR A C   1 
ATOM   1153  O  O   . THR A 1 310 ? 102.408 66.850  140.752 1.00 150.35 ? 309 THR A O   1 
ATOM   1154  C  CB  . THR A 1 310 ? 104.080 69.441  140.581 1.00 144.05 ? 309 THR A CB  1 
ATOM   1155  O  OG1 . THR A 1 310 ? 104.746 69.481  141.827 1.00 195.61 ? 309 THR A OG1 1 
ATOM   1156  C  CG2 . THR A 1 310 ? 102.637 69.789  140.848 1.00 164.26 ? 309 THR A CG2 1 
ATOM   1157  N  N   . PRO A 1 311 ? 104.344 65.952  141.391 1.00 132.49 ? 310 PRO A N   1 
ATOM   1158  C  CA  . PRO A 1 311 ? 103.726 64.691  141.810 1.00 110.48 ? 310 PRO A CA  1 
ATOM   1159  C  C   . PRO A 1 311 ? 102.493 64.758  142.732 1.00 116.83 ? 310 PRO A C   1 
ATOM   1160  O  O   . PRO A 1 311 ? 101.438 64.304  142.331 1.00 129.36 ? 310 PRO A O   1 
ATOM   1161  C  CB  . PRO A 1 311 ? 104.883 63.985  142.522 1.00 177.88 ? 310 PRO A CB  1 
ATOM   1162  C  CG  . PRO A 1 311 ? 106.107 64.589  141.916 1.00 190.64 ? 310 PRO A CG  1 
ATOM   1163  C  CD  . PRO A 1 311 ? 105.774 66.039  141.703 1.00 130.27 ? 310 PRO A CD  1 
ATOM   1164  N  N   . ASN A 1 312 ? 102.602 65.319  143.940 1.00 116.47 ? 311 ASN A N   1 
ATOM   1165  C  CA  . ASN A 1 312 ? 101.599 65.194  144.983 1.00 144.40 ? 311 ASN A CA  1 
ATOM   1166  C  C   . ASN A 1 312 ? 100.607 66.360  144.940 1.00 152.98 ? 311 ASN A C   1 
ATOM   1167  O  O   . ASN A 1 312 ? 100.318 66.983  145.958 1.00 149.88 ? 311 ASN A O   1 
ATOM   1168  C  CB  . ASN A 1 312 ? 102.295 65.138  146.342 1.00 175.27 ? 311 ASN A CB  1 
ATOM   1169  C  CG  . ASN A 1 312 ? 101.384 64.823  147.512 1.00 247.52 ? 311 ASN A CG  1 
ATOM   1170  O  OD1 . ASN A 1 312 ? 100.369 64.147  147.359 1.00 295.12 ? 311 ASN A OD1 1 
ATOM   1171  N  ND2 . ASN A 1 312 ? 101.741 65.297  148.698 1.00 291.45 ? 311 ASN A ND2 1 
ATOM   1172  N  N   . TYR A 1 313 ? 100.049 66.655  143.769 1.00 123.22 ? 312 TYR A N   1 
ATOM   1173  C  CA  . TYR A 1 313 ? 99.352  67.914  143.594 1.00 145.72 ? 312 TYR A CA  1 
ATOM   1174  C  C   . TYR A 1 313 ? 98.028  68.061  144.352 1.00 169.50 ? 312 TYR A C   1 
ATOM   1175  O  O   . TYR A 1 313 ? 97.577  69.194  144.509 1.00 233.66 ? 312 TYR A O   1 
ATOM   1176  C  CB  . TYR A 1 313 ? 99.046  68.100  142.129 1.00 152.22 ? 312 TYR A CB  1 
ATOM   1177  C  CG  . TYR A 1 313 ? 98.080  67.137  141.484 1.00 141.94 ? 312 TYR A CG  1 
ATOM   1178  C  CD1 . TYR A 1 313 ? 98.554  65.970  140.905 1.00 159.98 ? 312 TYR A CD1 1 
ATOM   1179  C  CD2 . TYR A 1 313 ? 96.722  67.415  141.421 1.00 186.17 ? 312 TYR A CD2 1 
ATOM   1180  C  CE1 . TYR A 1 313 ? 97.702  65.088  140.273 1.00 169.89 ? 312 TYR A CE1 1 
ATOM   1181  C  CE2 . TYR A 1 313 ? 95.849  66.532  140.800 1.00 243.07 ? 312 TYR A CE2 1 
ATOM   1182  C  CZ  . TYR A 1 313 ? 96.345  65.368  140.225 1.00 217.58 ? 312 TYR A CZ  1 
ATOM   1183  O  OH  . TYR A 1 313 ? 95.495  64.495  139.619 1.00 255.80 ? 312 TYR A OH  1 
ATOM   1184  N  N   . ARG A 1 314 ? 97.420  66.972  144.831 1.00 154.13 ? 313 ARG A N   1 
ATOM   1185  C  CA  . ARG A 1 314 ? 96.273  67.077  145.722 1.00 182.63 ? 313 ARG A CA  1 
ATOM   1186  C  C   . ARG A 1 314 ? 96.683  67.230  147.197 1.00 214.33 ? 313 ARG A C   1 
ATOM   1187  O  O   . ARG A 1 314 ? 95.798  67.417  148.042 1.00 260.11 ? 313 ARG A O   1 
ATOM   1188  C  CB  . ARG A 1 314 ? 95.389  65.842  145.537 1.00 209.72 ? 313 ARG A CB  1 
ATOM   1189  C  CG  . ARG A 1 314 ? 94.875  65.680  144.118 1.00 185.24 ? 313 ARG A CG  1 
ATOM   1190  C  CD  . ARG A 1 314 ? 93.786  64.629  144.009 1.00 209.01 ? 313 ARG A CD  1 
ATOM   1191  N  NE  . ARG A 1 314 ? 93.296  64.494  142.637 1.00 282.92 ? 313 ARG A NE  1 
ATOM   1192  C  CZ  . ARG A 1 314 ? 92.529  65.370  141.972 1.00 324.76 ? 313 ARG A CZ  1 
ATOM   1193  N  NH1 . ARG A 1 314 ? 92.136  65.095  140.736 1.00 344.97 ? 313 ARG A NH1 1 
ATOM   1194  N  NH2 . ARG A 1 314 ? 92.146  66.512  142.524 1.00 302.32 ? 313 ARG A NH2 1 
ATOM   1195  N  N   . GLY A 1 315 ? 97.996  67.150  147.515 1.00 152.51 ? 314 GLY A N   1 
ATOM   1196  C  CA  . GLY A 1 315 ? 98.501  67.193  148.879 1.00 178.23 ? 314 GLY A CA  1 
ATOM   1197  C  C   . GLY A 1 315 ? 98.973  68.573  149.336 1.00 189.44 ? 314 GLY A C   1 
ATOM   1198  O  O   . GLY A 1 315 ? 98.722  69.583  148.695 1.00 209.44 ? 314 GLY A O   1 
ATOM   1199  N  N   . GLU A 1 316 ? 99.673  68.575  150.479 1.00 253.34 ? 315 GLU A N   1 
ATOM   1200  C  CA  . GLU A 1 316 ? 100.217 69.777  151.098 1.00 257.04 ? 315 GLU A CA  1 
ATOM   1201  C  C   . GLU A 1 316 ? 101.573 70.111  150.474 1.00 206.22 ? 315 GLU A C   1 
ATOM   1202  O  O   . GLU A 1 316 ? 101.791 71.242  150.047 1.00 218.04 ? 315 GLU A O   1 
ATOM   1203  C  CB  . GLU A 1 316 ? 100.318 69.568  152.613 1.00 305.93 ? 315 GLU A CB  1 
ATOM   1204  C  CG  . GLU A 1 316 ? 100.916 70.744  153.370 1.00 407.60 ? 315 GLU A CG  1 
ATOM   1205  C  CD  . GLU A 1 316 ? 100.848 70.659  154.888 1.00 515.17 ? 315 GLU A CD  1 
ATOM   1206  O  OE1 . GLU A 1 316 ? 100.332 69.649  155.416 1.00 558.65 ? 315 GLU A OE1 1 
ATOM   1207  O  OE2 . GLU A 1 316 ? 101.316 71.611  155.546 1.00 577.19 ? 315 GLU A OE2 1 
ATOM   1208  N  N   . ASN A 1 317 ? 102.476 69.120  150.444 1.00 198.89 ? 316 ASN A N   1 
ATOM   1209  C  CA  . ASN A 1 317 ? 103.829 69.262  149.931 1.00 201.81 ? 316 ASN A CA  1 
ATOM   1210  C  C   . ASN A 1 317 ? 103.929 68.519  148.603 1.00 158.44 ? 316 ASN A C   1 
ATOM   1211  O  O   . ASN A 1 317 ? 103.787 67.302  148.574 1.00 201.60 ? 316 ASN A O   1 
ATOM   1212  C  CB  . ASN A 1 317 ? 104.839 68.763  150.970 1.00 229.15 ? 316 ASN A CB  1 
ATOM   1213  C  CG  . ASN A 1 317 ? 106.286 68.763  150.507 1.00 245.85 ? 316 ASN A CG  1 
ATOM   1214  O  OD1 . ASN A 1 317 ? 106.576 68.785  149.310 1.00 169.80 ? 316 ASN A OD1 1 
ATOM   1215  N  ND2 . ASN A 1 317 ? 107.213 68.726  151.453 1.00 261.01 ? 316 ASN A ND2 1 
ATOM   1216  N  N   . SER A 1 318 ? 104.206 69.241  147.510 1.00 171.81 ? 317 SER A N   1 
ATOM   1217  C  CA  . SER A 1 318 ? 104.011 68.697  146.173 1.00 213.88 ? 317 SER A CA  1 
ATOM   1218  C  C   . SER A 1 318 ? 105.038 67.622  145.783 1.00 177.93 ? 317 SER A C   1 
ATOM   1219  O  O   . SER A 1 318 ? 104.792 66.882  144.837 1.00 181.02 ? 317 SER A O   1 
ATOM   1220  C  CB  . SER A 1 318 ? 103.960 69.770  145.146 1.00 272.13 ? 317 SER A CB  1 
ATOM   1221  O  OG  . SER A 1 318 ? 102.919 70.703  145.417 1.00 262.03 ? 317 SER A OG  1 
ATOM   1222  N  N   . TRP A 1 319 ? 106.157 67.490  146.495 1.00 136.88 ? 318 TRP A N   1 
ATOM   1223  C  CA  . TRP A 1 319 ? 107.104 66.418  146.203 1.00 169.22 ? 318 TRP A CA  1 
ATOM   1224  C  C   . TRP A 1 319 ? 107.112 65.282  147.236 1.00 211.84 ? 318 TRP A C   1 
ATOM   1225  O  O   . TRP A 1 319 ? 108.001 64.433  147.178 1.00 211.69 ? 318 TRP A O   1 
ATOM   1226  C  CB  . TRP A 1 319 ? 108.496 67.057  146.104 1.00 208.21 ? 318 TRP A CB  1 
ATOM   1227  C  CG  . TRP A 1 319 ? 108.536 67.998  144.948 1.00 166.83 ? 318 TRP A CG  1 
ATOM   1228  C  CD1 . TRP A 1 319 ? 108.354 69.333  145.002 1.00 156.01 ? 318 TRP A CD1 1 
ATOM   1229  C  CD2 . TRP A 1 319 ? 108.734 67.655  143.564 1.00 159.62 ? 318 TRP A CD2 1 
ATOM   1230  N  NE1 . TRP A 1 319 ? 108.444 69.851  143.744 1.00 191.92 ? 318 TRP A NE1 1 
ATOM   1231  C  CE2 . TRP A 1 319 ? 108.673 68.850  142.838 1.00 172.93 ? 318 TRP A CE2 1 
ATOM   1232  C  CE3 . TRP A 1 319 ? 108.965 66.474  142.863 1.00 154.69 ? 318 TRP A CE3 1 
ATOM   1233  C  CZ2 . TRP A 1 319 ? 108.824 68.894  141.452 1.00 161.48 ? 318 TRP A CZ2 1 
ATOM   1234  C  CZ3 . TRP A 1 319 ? 109.124 66.523  141.498 1.00 165.88 ? 318 TRP A CZ3 1 
ATOM   1235  C  CH2 . TRP A 1 319 ? 109.035 67.714  140.792 1.00 126.90 ? 318 TRP A CH2 1 
ATOM   1236  N  N   . PHE A 1 320 ? 106.137 65.272  148.164 1.00 198.22 ? 319 PHE A N   1 
ATOM   1237  C  CA  . PHE A 1 320 ? 106.118 64.436  149.352 1.00 172.55 ? 319 PHE A CA  1 
ATOM   1238  C  C   . PHE A 1 320 ? 107.312 64.688  150.306 1.00 207.71 ? 319 PHE A C   1 
ATOM   1239  O  O   . PHE A 1 320 ? 108.319 65.317  149.977 1.00 214.92 ? 319 PHE A O   1 
ATOM   1240  C  CB  . PHE A 1 320 ? 106.062 62.978  148.919 1.00 171.57 ? 319 PHE A CB  1 
ATOM   1241  C  CG  . PHE A 1 320 ? 105.029 62.543  147.910 1.00 164.27 ? 319 PHE A CG  1 
ATOM   1242  C  CD1 . PHE A 1 320 ? 103.691 62.361  148.265 1.00 175.26 ? 319 PHE A CD1 1 
ATOM   1243  C  CD2 . PHE A 1 320 ? 105.416 62.269  146.603 1.00 156.42 ? 319 PHE A CD2 1 
ATOM   1244  C  CE1 . PHE A 1 320 ? 102.761 61.918  147.323 1.00 184.28 ? 319 PHE A CE1 1 
ATOM   1245  C  CE2 . PHE A 1 320 ? 104.483 61.841  145.665 1.00 191.63 ? 319 PHE A CE2 1 
ATOM   1246  C  CZ  . PHE A 1 320 ? 103.155 61.671  146.020 1.00 153.64 ? 319 PHE A CZ  1 
ATOM   1247  N  N   . SER A 1 321 ? 107.203 64.164  151.534 1.00 259.48 ? 320 SER A N   1 
ATOM   1248  C  CA  . SER A 1 321 ? 108.164 64.427  152.601 1.00 293.52 ? 320 SER A CA  1 
ATOM   1249  C  C   . SER A 1 321 ? 109.390 63.502  152.565 1.00 297.11 ? 320 SER A C   1 
ATOM   1250  O  O   . SER A 1 321 ? 110.342 63.755  153.301 1.00 330.32 ? 320 SER A O   1 
ATOM   1251  C  CB  . SER A 1 321 ? 107.465 64.328  153.946 1.00 363.18 ? 320 SER A CB  1 
ATOM   1252  O  OG  . SER A 1 321 ? 108.306 64.766  155.005 1.00 420.72 ? 320 SER A OG  1 
ATOM   1253  N  N   . THR A 1 322 ? 109.393 62.435  151.738 1.00 303.93 ? 321 THR A N   1 
ATOM   1254  C  CA  . THR A 1 322 ? 110.243 61.260  151.959 1.00 327.08 ? 321 THR A CA  1 
ATOM   1255  C  C   . THR A 1 322 ? 110.725 60.643  150.640 1.00 258.83 ? 321 THR A C   1 
ATOM   1256  O  O   . THR A 1 322 ? 110.047 60.759  149.624 1.00 259.46 ? 321 THR A O   1 
ATOM   1257  C  CB  . THR A 1 322 ? 109.489 60.197  152.781 1.00 400.57 ? 321 THR A CB  1 
ATOM   1258  O  OG1 . THR A 1 322 ? 108.924 60.790  153.950 1.00 445.11 ? 321 THR A OG1 1 
ATOM   1259  C  CG2 . THR A 1 322 ? 110.340 59.032  153.251 1.00 430.07 ? 321 THR A CG2 1 
ATOM   1260  N  N   . GLN A 1 323 ? 111.899 59.976  150.677 1.00 269.72 ? 322 GLN A N   1 
ATOM   1261  C  CA  . GLN A 1 323 ? 112.450 59.098  149.633 1.00 306.57 ? 322 GLN A CA  1 
ATOM   1262  C  C   . GLN A 1 323 ? 112.406 59.741  148.237 1.00 258.91 ? 322 GLN A C   1 
ATOM   1263  O  O   . GLN A 1 323 ? 112.009 59.119  147.239 1.00 254.95 ? 322 GLN A O   1 
ATOM   1264  C  CB  . GLN A 1 323 ? 111.816 57.694  149.680 1.00 377.09 ? 322 GLN A CB  1 
ATOM   1265  C  CG  . GLN A 1 323 ? 110.305 57.574  149.439 1.00 389.63 ? 322 GLN A CG  1 
ATOM   1266  C  CD  . GLN A 1 323 ? 109.818 56.142  149.367 1.00 405.01 ? 322 GLN A CD  1 
ATOM   1267  O  OE1 . GLN A 1 323 ? 110.522 55.233  148.926 1.00 437.74 ? 322 GLN A OE1 1 
ATOM   1268  N  NE2 . GLN A 1 323 ? 108.593 55.913  149.819 1.00 392.22 ? 322 GLN A NE2 1 
ATOM   1269  N  N   . VAL A 1 324 ? 112.872 60.996  148.185 1.00 253.45 ? 323 VAL A N   1 
ATOM   1270  C  CA  . VAL A 1 324 ? 112.721 61.892  147.042 1.00 280.28 ? 323 VAL A CA  1 
ATOM   1271  C  C   . VAL A 1 324 ? 113.287 61.295  145.746 1.00 231.16 ? 323 VAL A C   1 
ATOM   1272  O  O   . VAL A 1 324 ? 112.757 61.600  144.670 1.00 214.11 ? 323 VAL A O   1 
ATOM   1273  C  CB  . VAL A 1 324 ? 113.350 63.266  147.370 1.00 344.26 ? 323 VAL A CB  1 
ATOM   1274  C  CG1 . VAL A 1 324 ? 114.866 63.218  147.535 1.00 341.12 ? 323 VAL A CG1 1 
ATOM   1275  C  CG2 . VAL A 1 324 ? 112.976 64.322  146.341 1.00 393.60 ? 323 VAL A CG2 1 
ATOM   1276  N  N   . ASP A 1 325 ? 114.349 60.470  145.838 1.00 226.26 ? 324 ASP A N   1 
ATOM   1277  C  CA  . ASP A 1 325 ? 114.971 59.852  144.664 1.00 289.25 ? 324 ASP A CA  1 
ATOM   1278  C  C   . ASP A 1 325 ? 114.022 58.892  143.928 1.00 286.52 ? 324 ASP A C   1 
ATOM   1279  O  O   . ASP A 1 325 ? 114.129 58.768  142.701 1.00 250.68 ? 324 ASP A O   1 
ATOM   1280  C  CB  . ASP A 1 325 ? 116.305 59.173  145.012 1.00 321.38 ? 324 ASP A CB  1 
ATOM   1281  C  CG  . ASP A 1 325 ? 116.265 58.132  146.118 1.00 365.33 ? 324 ASP A CG  1 
ATOM   1282  O  OD1 . ASP A 1 325 ? 115.219 58.016  146.784 1.00 371.06 ? 324 ASP A OD1 1 
ATOM   1283  O  OD2 . ASP A 1 325 ? 117.289 57.445  146.304 1.00 419.92 ? 324 ASP A OD2 1 
ATOM   1284  N  N   . THR A 1 326 ? 113.104 58.223  144.650 1.00 279.65 ? 325 THR A N   1 
ATOM   1285  C  CA  . THR A 1 326 ? 112.052 57.428  144.018 1.00 262.76 ? 325 THR A CA  1 
ATOM   1286  C  C   . THR A 1 326 ? 111.081 58.344  143.270 1.00 237.37 ? 325 THR A C   1 
ATOM   1287  O  O   . THR A 1 326 ? 110.637 57.989  142.185 1.00 210.25 ? 325 THR A O   1 
ATOM   1288  C  CB  . THR A 1 326 ? 111.292 56.533  145.010 1.00 288.58 ? 325 THR A CB  1 
ATOM   1289  O  OG1 . THR A 1 326 ? 110.520 57.325  145.914 1.00 299.27 ? 325 THR A OG1 1 
ATOM   1290  C  CG2 . THR A 1 326 ? 112.212 55.630  145.803 1.00 320.83 ? 325 THR A CG2 1 
ATOM   1291  N  N   . VAL A 1 327 ? 110.774 59.517  143.846 1.00 216.79 ? 326 VAL A N   1 
ATOM   1292  C  CA  . VAL A 1 327 ? 109.880 60.493  143.230 1.00 200.95 ? 326 VAL A CA  1 
ATOM   1293  C  C   . VAL A 1 327 ? 110.534 61.061  141.961 1.00 167.71 ? 326 VAL A C   1 
ATOM   1294  O  O   . VAL A 1 327 ? 109.927 61.079  140.897 1.00 149.59 ? 326 VAL A O   1 
ATOM   1295  C  CB  . VAL A 1 327 ? 109.460 61.598  144.224 1.00 191.55 ? 326 VAL A CB  1 
ATOM   1296  C  CG1 . VAL A 1 327 ? 108.346 62.438  143.632 1.00 254.60 ? 326 VAL A CG1 1 
ATOM   1297  C  CG2 . VAL A 1 327 ? 108.998 61.050  145.570 1.00 170.77 ? 326 VAL A CG2 1 
ATOM   1298  N  N   . ALA A 1 328 ? 111.783 61.512  142.056 1.00 154.11 ? 327 ALA A N   1 
ATOM   1299  C  CA  . ALA A 1 328 ? 112.561 61.877  140.874 1.00 171.81 ? 327 ALA A CA  1 
ATOM   1300  C  C   . ALA A 1 328 ? 112.627 60.764  139.815 1.00 169.97 ? 327 ALA A C   1 
ATOM   1301  O  O   . ALA A 1 328 ? 112.556 61.051  138.621 1.00 184.35 ? 327 ALA A O   1 
ATOM   1302  C  CB  . ALA A 1 328 ? 113.950 62.273  141.298 1.00 216.00 ? 327 ALA A CB  1 
ATOM   1303  N  N   . THR A 1 329 ? 112.752 59.497  140.235 1.00 189.77 ? 328 THR A N   1 
ATOM   1304  C  CA  . THR A 1 329 ? 112.722 58.368  139.316 1.00 209.71 ? 328 THR A CA  1 
ATOM   1305  C  C   . THR A 1 329 ? 111.374 58.294  138.588 1.00 199.79 ? 328 THR A C   1 
ATOM   1306  O  O   . THR A 1 329 ? 111.382 58.056  137.376 1.00 161.84 ? 328 THR A O   1 
ATOM   1307  C  CB  . THR A 1 329 ? 113.078 57.062  140.042 1.00 287.48 ? 328 THR A CB  1 
ATOM   1308  O  OG1 . THR A 1 329 ? 114.399 57.218  140.562 1.00 291.36 ? 328 THR A OG1 1 
ATOM   1309  C  CG2 . THR A 1 329 ? 113.033 55.827  139.166 1.00 365.64 ? 328 THR A CG2 1 
ATOM   1310  N  N   . LYS A 1 330 ? 110.238 58.494  139.296 1.00 202.94 ? 329 LYS A N   1 
ATOM   1311  C  CA  . LYS A 1 330 ? 108.926 58.556  138.653 1.00 222.97 ? 329 LYS A CA  1 
ATOM   1312  C  C   . LYS A 1 330 ? 108.955 59.590  137.525 1.00 168.13 ? 329 LYS A C   1 
ATOM   1313  O  O   . LYS A 1 330 ? 108.536 59.288  136.406 1.00 162.74 ? 329 LYS A O   1 
ATOM   1314  C  CB  . LYS A 1 330 ? 107.782 58.883  139.630 1.00 222.50 ? 329 LYS A CB  1 
ATOM   1315  C  CG  . LYS A 1 330 ? 107.458 57.816  140.664 1.00 244.83 ? 329 LYS A CG  1 
ATOM   1316  C  CD  . LYS A 1 330 ? 106.328 58.229  141.593 1.00 264.06 ? 329 LYS A CD  1 
ATOM   1317  C  CE  . LYS A 1 330 ? 106.077 57.240  142.715 1.00 327.23 ? 329 LYS A CE  1 
ATOM   1318  N  NZ  . LYS A 1 330 ? 105.274 56.070  142.278 1.00 347.01 ? 329 LYS A NZ  1 
ATOM   1319  N  N   . VAL A 1 331 ? 109.455 60.798  137.819 1.00 135.19 ? 330 VAL A N   1 
ATOM   1320  C  CA  . VAL A 1 331 ? 109.489 61.872  136.838 1.00 162.87 ? 330 VAL A CA  1 
ATOM   1321  C  C   . VAL A 1 331 ? 110.389 61.494  135.662 1.00 135.95 ? 330 VAL A C   1 
ATOM   1322  O  O   . VAL A 1 331 ? 110.002 61.698  134.512 1.00 118.58 ? 330 VAL A O   1 
ATOM   1323  C  CB  . VAL A 1 331 ? 109.904 63.220  137.463 1.00 153.93 ? 330 VAL A CB  1 
ATOM   1324  C  CG1 . VAL A 1 331 ? 110.062 64.356  136.458 1.00 129.89 ? 330 VAL A CG1 1 
ATOM   1325  C  CG2 . VAL A 1 331 ? 108.905 63.676  138.492 1.00 186.44 ? 330 VAL A CG2 1 
ATOM   1326  N  N   . LYS A 1 332 ? 111.569 60.958  135.949 1.00 124.92 ? 331 LYS A N   1 
ATOM   1327  C  CA  . LYS A 1 332 ? 112.534 60.619  134.919 1.00 162.65 ? 331 LYS A CA  1 
ATOM   1328  C  C   . LYS A 1 332 ? 111.904 59.709  133.855 1.00 184.87 ? 331 LYS A C   1 
ATOM   1329  O  O   . LYS A 1 332 ? 112.185 59.871  132.658 1.00 156.29 ? 331 LYS A O   1 
ATOM   1330  C  CB  . LYS A 1 332 ? 113.753 59.978  135.589 1.00 211.85 ? 331 LYS A CB  1 
ATOM   1331  C  CG  . LYS A 1 332 ? 114.815 59.443  134.639 1.00 263.41 ? 331 LYS A CG  1 
ATOM   1332  C  CD  . LYS A 1 332 ? 116.029 58.924  135.362 1.00 305.69 ? 331 LYS A CD  1 
ATOM   1333  C  CE  . LYS A 1 332 ? 117.163 58.543  134.433 1.00 336.61 ? 331 LYS A CE  1 
ATOM   1334  N  NZ  . LYS A 1 332 ? 118.470 58.545  135.134 1.00 384.88 ? 331 LYS A NZ  1 
ATOM   1335  N  N   . ASP A 1 333 ? 111.077 58.744  134.299 1.00 197.17 ? 332 ASP A N   1 
ATOM   1336  C  CA  . ASP A 1 333 ? 110.333 57.866  133.410 1.00 229.49 ? 332 ASP A CA  1 
ATOM   1337  C  C   . ASP A 1 333 ? 109.188 58.619  132.727 1.00 177.16 ? 332 ASP A C   1 
ATOM   1338  O  O   . ASP A 1 333 ? 108.946 58.415  131.543 1.00 162.51 ? 332 ASP A O   1 
ATOM   1339  C  CB  . ASP A 1 333 ? 109.830 56.638  134.181 1.00 271.58 ? 332 ASP A CB  1 
ATOM   1340  C  CG  . ASP A 1 333 ? 110.912 55.676  134.668 1.00 299.94 ? 332 ASP A CG  1 
ATOM   1341  O  OD1 . ASP A 1 333 ? 112.093 55.831  134.274 1.00 315.62 ? 332 ASP A OD1 1 
ATOM   1342  O  OD2 . ASP A 1 333 ? 110.567 54.764  135.445 1.00 333.93 ? 332 ASP A OD2 1 
ATOM   1343  N  N   . ALA A 1 334 ? 108.474 59.471  133.476 1.00 171.87 ? 333 ALA A N   1 
ATOM   1344  C  CA  . ALA A 1 334 ? 107.277 60.155  132.998 1.00 164.18 ? 333 ALA A CA  1 
ATOM   1345  C  C   . ALA A 1 334 ? 107.581 61.045  131.805 1.00 131.85 ? 333 ALA A C   1 
ATOM   1346  O  O   . ALA A 1 334 ? 106.789 61.077  130.857 1.00 126.67 ? 333 ALA A O   1 
ATOM   1347  C  CB  . ALA A 1 334 ? 106.637 60.968  134.111 1.00 146.98 ? 333 ALA A CB  1 
ATOM   1348  N  N   . LEU A 1 335 ? 108.705 61.766  131.854 1.00 130.10 ? 334 LEU A N   1 
ATOM   1349  C  CA  . LEU A 1 335 ? 109.003 62.735  130.809 1.00 147.85 ? 334 LEU A CA  1 
ATOM   1350  C  C   . LEU A 1 335 ? 109.110 62.036  129.452 1.00 167.31 ? 334 LEU A C   1 
ATOM   1351  O  O   . LEU A 1 335 ? 108.596 62.534  128.451 1.00 114.02 ? 334 LEU A O   1 
ATOM   1352  C  CB  . LEU A 1 335 ? 110.303 63.458  131.143 1.00 149.62 ? 334 LEU A CB  1 
ATOM   1353  C  CG  . LEU A 1 335 ? 110.266 64.325  132.397 1.00 154.51 ? 334 LEU A CG  1 
ATOM   1354  C  CD1 . LEU A 1 335 ? 111.659 64.673  132.862 1.00 206.37 ? 334 LEU A CD1 1 
ATOM   1355  C  CD2 . LEU A 1 335 ? 109.550 65.593  132.146 1.00 149.90 ? 334 LEU A CD2 1 
ATOM   1356  N  N   . GLU A 1 336 ? 109.773 60.873  129.423 1.00 189.89 ? 335 GLU A N   1 
ATOM   1357  C  CA  . GLU A 1 336 ? 109.926 60.085  128.208 1.00 233.51 ? 335 GLU A CA  1 
ATOM   1358  C  C   . GLU A 1 336 ? 108.565 59.656  127.644 1.00 184.44 ? 335 GLU A C   1 
ATOM   1359  O  O   . GLU A 1 336 ? 108.326 59.791  126.440 1.00 179.36 ? 335 GLU A O   1 
ATOM   1360  C  CB  . GLU A 1 336 ? 110.837 58.897  128.520 1.00 256.91 ? 335 GLU A CB  1 
ATOM   1361  C  CG  . GLU A 1 336 ? 111.082 57.967  127.344 1.00 328.30 ? 335 GLU A CG  1 
ATOM   1362  C  CD  . GLU A 1 336 ? 111.966 56.772  127.664 1.00 415.07 ? 335 GLU A CD  1 
ATOM   1363  O  OE1 . GLU A 1 336 ? 112.471 56.683  128.807 1.00 429.44 ? 335 GLU A OE1 1 
ATOM   1364  O  OE2 . GLU A 1 336 ? 112.147 55.924  126.765 1.00 494.41 ? 335 GLU A OE2 1 
ATOM   1365  N  N   . PHE A 1 337 ? 107.684 59.140  128.508 1.00 142.99 ? 336 PHE A N   1 
ATOM   1366  C  CA  . PHE A 1 337 ? 106.385 58.658  128.077 1.00 161.03 ? 336 PHE A CA  1 
ATOM   1367  C  C   . PHE A 1 337 ? 105.589 59.798  127.459 1.00 124.52 ? 336 PHE A C   1 
ATOM   1368  O  O   . PHE A 1 337 ? 105.035 59.656  126.367 1.00 143.11 ? 336 PHE A O   1 
ATOM   1369  C  CB  . PHE A 1 337 ? 105.606 58.023  129.236 1.00 193.09 ? 336 PHE A CB  1 
ATOM   1370  C  CG  . PHE A 1 337 ? 104.182 57.671  128.887 1.00 205.63 ? 336 PHE A CG  1 
ATOM   1371  C  CD1 . PHE A 1 337 ? 103.869 56.491  128.231 1.00 246.21 ? 336 PHE A CD1 1 
ATOM   1372  C  CD2 . PHE A 1 337 ? 103.149 58.538  129.199 1.00 176.16 ? 336 PHE A CD2 1 
ATOM   1373  C  CE1 . PHE A 1 337 ? 102.546 56.200  127.915 1.00 295.31 ? 336 PHE A CE1 1 
ATOM   1374  C  CE2 . PHE A 1 337 ? 101.830 58.267  128.885 1.00 198.09 ? 336 PHE A CE2 1 
ATOM   1375  C  CZ  . PHE A 1 337 ? 101.531 57.084  128.247 1.00 261.84 ? 336 PHE A CZ  1 
ATOM   1376  N  N   . TRP A 1 338 ? 105.503 60.920  128.167 1.00 115.14 ? 337 TRP A N   1 
ATOM   1377  C  CA  . TRP A 1 338 ? 104.616 61.976  127.713 1.00 120.53 ? 337 TRP A CA  1 
ATOM   1378  C  C   . TRP A 1 338 ? 105.179 62.673  126.483 1.00 127.28 ? 337 TRP A C   1 
ATOM   1379  O  O   . TRP A 1 338 ? 104.392 63.135  125.663 1.00 145.70 ? 337 TRP A O   1 
ATOM   1380  C  CB  . TRP A 1 338 ? 104.342 62.935  128.858 1.00 111.29 ? 337 TRP A CB  1 
ATOM   1381  C  CG  . TRP A 1 338 ? 103.417 62.361  129.888 1.00 119.94 ? 337 TRP A CG  1 
ATOM   1382  C  CD1 . TRP A 1 338 ? 103.670 61.951  131.175 1.00 119.20 ? 337 TRP A CD1 1 
ATOM   1383  C  CD2 . TRP A 1 338 ? 102.012 62.161  129.678 1.00 123.99 ? 337 TRP A CD2 1 
ATOM   1384  N  NE1 . TRP A 1 338 ? 102.528 61.509  131.787 1.00 93.61  ? 337 TRP A NE1 1 
ATOM   1385  C  CE2 . TRP A 1 338 ? 101.494 61.625  130.905 1.00 112.86 ? 337 TRP A CE2 1 
ATOM   1386  C  CE3 . TRP A 1 338 ? 101.163 62.390  128.578 1.00 96.54  ? 337 TRP A CE3 1 
ATOM   1387  C  CZ2 . TRP A 1 338 ? 100.151 61.310  131.069 1.00 118.17 ? 337 TRP A CZ2 1 
ATOM   1388  C  CZ3 . TRP A 1 338 ? 99.827  62.086  128.753 1.00 133.17 ? 337 TRP A CZ3 1 
ATOM   1389  C  CH2 . TRP A 1 338 ? 99.336  61.560  129.971 1.00 186.17 ? 337 TRP A CH2 1 
ATOM   1390  N  N   . LEU A 1 339 ? 106.510 62.742  126.328 1.00 122.21 ? 338 LEU A N   1 
ATOM   1391  C  CA  . LEU A 1 339 ? 107.072 63.222  125.071 1.00 153.23 ? 338 LEU A CA  1 
ATOM   1392  C  C   . LEU A 1 339 ? 106.663 62.304  123.915 1.00 175.61 ? 338 LEU A C   1 
ATOM   1393  O  O   . LEU A 1 339 ? 106.266 62.796  122.856 1.00 137.16 ? 338 LEU A O   1 
ATOM   1394  C  CB  . LEU A 1 339 ? 108.589 63.301  125.218 1.00 143.42 ? 338 LEU A CB  1 
ATOM   1395  C  CG  . LEU A 1 339 ? 109.078 64.506  126.000 1.00 154.34 ? 338 LEU A CG  1 
ATOM   1396  C  CD1 . LEU A 1 339 ? 110.526 64.318  126.418 1.00 220.87 ? 338 LEU A CD1 1 
ATOM   1397  C  CD2 . LEU A 1 339 ? 108.944 65.758  125.174 1.00 158.98 ? 338 LEU A CD2 1 
ATOM   1398  N  N   . GLN A 1 340 ? 106.750 60.978  124.121 1.00 174.59 ? 339 GLN A N   1 
ATOM   1399  C  CA  . GLN A 1 340 ? 106.302 60.012  123.127 1.00 197.72 ? 339 GLN A CA  1 
ATOM   1400  C  C   . GLN A 1 340 ? 104.806 60.173  122.817 1.00 199.85 ? 339 GLN A C   1 
ATOM   1401  O  O   . GLN A 1 340 ? 104.394 59.898  121.685 1.00 243.01 ? 339 GLN A O   1 
ATOM   1402  C  CB  . GLN A 1 340 ? 106.627 58.584  123.591 1.00 241.03 ? 339 GLN A CB  1 
ATOM   1403  C  CG  . GLN A 1 340 ? 108.103 58.211  123.510 1.00 245.57 ? 339 GLN A CG  1 
ATOM   1404  C  CD  . GLN A 1 340 ? 108.651 58.069  122.110 1.00 330.84 ? 339 GLN A CD  1 
ATOM   1405  O  OE1 . GLN A 1 340 ? 109.842 58.265  121.882 1.00 366.92 ? 339 GLN A OE1 1 
ATOM   1406  N  NE2 . GLN A 1 340 ? 107.796 57.737  121.154 1.00 391.20 ? 339 GLN A NE2 1 
ATOM   1407  N  N   . ALA A 1 341 ? 104.000 60.596  123.806 1.00 191.69 ? 340 ALA A N   1 
ATOM   1408  C  CA  . ALA A 1 341 ? 102.585 60.914  123.623 1.00 198.91 ? 340 ALA A CA  1 
ATOM   1409  C  C   . ALA A 1 341 ? 102.366 62.205  122.819 1.00 169.69 ? 340 ALA A C   1 
ATOM   1410  O  O   . ALA A 1 341 ? 101.328 62.329  122.175 1.00 165.91 ? 340 ALA A O   1 
ATOM   1411  C  CB  . ALA A 1 341 ? 101.897 60.981  124.972 1.00 224.07 ? 340 ALA A CB  1 
ATOM   1412  N  N   . GLY A 1 342 ? 103.314 63.161  122.856 1.00 208.11 ? 341 GLY A N   1 
ATOM   1413  C  CA  . GLY A 1 342 ? 103.363 64.299  121.936 1.00 229.46 ? 341 GLY A CA  1 
ATOM   1414  C  C   . GLY A 1 342 ? 103.185 65.683  122.576 1.00 174.19 ? 341 GLY A C   1 
ATOM   1415  O  O   . GLY A 1 342 ? 102.979 66.665  121.862 1.00 150.12 ? 341 GLY A O   1 
ATOM   1416  N  N   . VAL A 1 343 ? 103.274 65.784  123.905 1.00 135.61 ? 342 VAL A N   1 
ATOM   1417  C  CA  . VAL A 1 343 ? 103.230 67.063  124.602 1.00 119.38 ? 342 VAL A CA  1 
ATOM   1418  C  C   . VAL A 1 343 ? 104.485 67.875  124.288 1.00 119.40 ? 342 VAL A C   1 
ATOM   1419  O  O   . VAL A 1 343 ? 105.510 67.279  124.008 1.00 144.04 ? 342 VAL A O   1 
ATOM   1420  C  CB  . VAL A 1 343 ? 103.143 66.856  126.122 1.00 133.05 ? 342 VAL A CB  1 
ATOM   1421  C  CG1 . VAL A 1 343 ? 101.999 65.927  126.509 1.00 163.82 ? 342 VAL A CG1 1 
ATOM   1422  C  CG2 . VAL A 1 343 ? 104.482 66.380  126.700 1.00 104.43 ? 342 VAL A CG2 1 
ATOM   1423  N  N   . ASP A 1 344 ? 104.409 69.215  124.368 1.00 110.83 ? 343 ASP A N   1 
ATOM   1424  C  CA  . ASP A 1 344 ? 105.498 70.087  123.949 1.00 125.42 ? 343 ASP A CA  1 
ATOM   1425  C  C   . ASP A 1 344 ? 106.429 70.462  125.093 1.00 117.83 ? 343 ASP A C   1 
ATOM   1426  O  O   . ASP A 1 344 ? 107.398 71.177  124.817 1.00 156.38 ? 343 ASP A O   1 
ATOM   1427  C  CB  . ASP A 1 344 ? 104.975 71.338  123.243 1.00 147.76 ? 343 ASP A CB  1 
ATOM   1428  C  CG  . ASP A 1 344 ? 104.099 70.961  122.058 1.00 210.10 ? 343 ASP A CG  1 
ATOM   1429  O  OD1 . ASP A 1 344 ? 104.632 70.409  121.069 1.00 274.31 ? 343 ASP A OD1 1 
ATOM   1430  O  OD2 . ASP A 1 344 ? 102.895 71.198  122.135 1.00 222.28 ? 343 ASP A OD2 1 
ATOM   1431  N  N   . GLY A 1 345 ? 106.166 70.002  126.325 1.00 89.74  ? 344 GLY A N   1 
ATOM   1432  C  CA  . GLY A 1 345 ? 107.013 70.392  127.433 1.00 96.00  ? 344 GLY A CA  1 
ATOM   1433  C  C   . GLY A 1 345 ? 106.385 70.116  128.778 1.00 76.20  ? 344 GLY A C   1 
ATOM   1434  O  O   . GLY A 1 345 ? 105.316 69.577  128.807 1.00 97.48  ? 344 GLY A O   1 
ATOM   1435  N  N   . PHE A 1 346 ? 107.039 70.499  129.864 1.00 80.12  ? 345 PHE A N   1 
ATOM   1436  C  CA  . PHE A 1 346 ? 106.576 70.181  131.207 1.00 94.07  ? 345 PHE A CA  1 
ATOM   1437  C  C   . PHE A 1 346 ? 106.744 71.337  132.176 1.00 90.84  ? 345 PHE A C   1 
ATOM   1438  O  O   . PHE A 1 346 ? 107.692 72.094  132.135 1.00 143.06 ? 345 PHE A O   1 
ATOM   1439  C  CB  . PHE A 1 346 ? 107.337 68.995  131.747 1.00 119.25 ? 345 PHE A CB  1 
ATOM   1440  C  CG  . PHE A 1 346 ? 107.139 67.832  130.816 1.00 130.54 ? 345 PHE A CG  1 
ATOM   1441  C  CD1 . PHE A 1 346 ? 105.973 67.081  130.860 1.00 108.81 ? 345 PHE A CD1 1 
ATOM   1442  C  CD2 . PHE A 1 346 ? 108.119 67.528  129.880 1.00 120.42 ? 345 PHE A CD2 1 
ATOM   1443  C  CE1 . PHE A 1 346 ? 105.823 66.019  129.986 1.00 151.65 ? 345 PHE A CE1 1 
ATOM   1444  C  CE2 . PHE A 1 346 ? 107.966 66.476  129.013 1.00 124.74 ? 345 PHE A CE2 1 
ATOM   1445  C  CZ  . PHE A 1 346 ? 106.818 65.723  129.064 1.00 186.27 ? 345 PHE A CZ  1 
ATOM   1446  N  N   . GLN A 1 347 ? 105.778 71.495  133.050 1.00 100.25 ? 346 GLN A N   1 
ATOM   1447  C  CA  . GLN A 1 347 ? 105.886 72.419  134.155 1.00 93.13  ? 346 GLN A CA  1 
ATOM   1448  C  C   . GLN A 1 347 ? 106.148 71.537  135.366 1.00 98.16  ? 346 GLN A C   1 
ATOM   1449  O  O   . GLN A 1 347 ? 105.543 70.468  135.527 1.00 112.39 ? 346 GLN A O   1 
ATOM   1450  C  CB  . GLN A 1 347 ? 104.607 73.263  134.304 1.00 98.82  ? 346 GLN A CB  1 
ATOM   1451  C  CG  . GLN A 1 347 ? 104.567 74.022  135.599 1.00 96.62  ? 346 GLN A CG  1 
ATOM   1452  C  CD  . GLN A 1 347 ? 103.533 75.104  135.673 1.00 109.03 ? 346 GLN A CD  1 
ATOM   1453  O  OE1 . GLN A 1 347 ? 103.849 76.265  135.383 1.00 105.79 ? 346 GLN A OE1 1 
ATOM   1454  N  NE2 . GLN A 1 347 ? 102.309 74.743  136.077 1.00 96.89  ? 346 GLN A NE2 1 
ATOM   1455  N  N   . VAL A 1 348 ? 107.041 72.004  136.230 1.00 97.71  ? 347 VAL A N   1 
ATOM   1456  C  CA  . VAL A 1 348 ? 107.187 71.453  137.559 1.00 97.64  ? 347 VAL A CA  1 
ATOM   1457  C  C   . VAL A 1 348 ? 107.206 72.612  138.541 1.00 89.68  ? 347 VAL A C   1 
ATOM   1458  O  O   . VAL A 1 348 ? 107.708 73.678  138.229 1.00 122.36 ? 347 VAL A O   1 
ATOM   1459  C  CB  . VAL A 1 348 ? 108.452 70.580  137.645 1.00 106.12 ? 347 VAL A CB  1 
ATOM   1460  C  CG1 . VAL A 1 348 ? 108.323 69.381  136.726 1.00 124.49 ? 347 VAL A CG1 1 
ATOM   1461  C  CG2 . VAL A 1 348 ? 109.740 71.343  137.352 1.00 116.64 ? 347 VAL A CG2 1 
ATOM   1462  N  N   . ARG A 1 349 ? 106.665 72.386  139.735 1.00 99.22  ? 348 ARG A N   1 
ATOM   1463  C  CA  . ARG A 1 349 ? 106.432 73.430  140.712 1.00 109.37 ? 348 ARG A CA  1 
ATOM   1464  C  C   . ARG A 1 349 ? 107.070 73.160  142.065 1.00 105.04 ? 348 ARG A C   1 
ATOM   1465  O  O   . ARG A 1 349 ? 107.481 72.059  142.360 1.00 118.61 ? 348 ARG A O   1 
ATOM   1466  C  CB  . ARG A 1 349 ? 104.912 73.543  140.801 1.00 94.58  ? 348 ARG A CB  1 
ATOM   1467  C  CG  . ARG A 1 349 ? 104.410 74.291  139.608 1.00 127.19 ? 348 ARG A CG  1 
ATOM   1468  C  CD  . ARG A 1 349 ? 103.045 74.908  139.819 1.00 128.87 ? 348 ARG A CD  1 
ATOM   1469  N  NE  . ARG A 1 349 ? 102.098 73.871  139.547 1.00 128.33 ? 348 ARG A NE  1 
ATOM   1470  C  CZ  . ARG A 1 349 ? 101.204 73.366  140.383 1.00 145.65 ? 348 ARG A CZ  1 
ATOM   1471  N  NH1 . ARG A 1 349 ? 100.352 72.499  139.874 1.00 187.34 ? 348 ARG A NH1 1 
ATOM   1472  N  NH2 . ARG A 1 349 ? 101.138 73.694  141.666 1.00 157.05 ? 348 ARG A NH2 1 
ATOM   1473  N  N   . ASP A 1 350 ? 107.097 74.207  142.874 1.00 119.44 ? 349 ASP A N   1 
ATOM   1474  C  CA  . ASP A 1 350 ? 107.481 74.161  144.275 1.00 124.55 ? 349 ASP A CA  1 
ATOM   1475  C  C   . ASP A 1 350 ? 108.913 73.661  144.419 1.00 88.57  ? 349 ASP A C   1 
ATOM   1476  O  O   . ASP A 1 350 ? 109.204 73.006  145.397 1.00 147.27 ? 349 ASP A O   1 
ATOM   1477  C  CB  . ASP A 1 350 ? 106.444 73.357  145.090 1.00 124.33 ? 349 ASP A CB  1 
ATOM   1478  C  CG  . ASP A 1 350 ? 104.995 73.827  144.975 1.00 158.96 ? 349 ASP A CG  1 
ATOM   1479  O  OD1 . ASP A 1 350 ? 104.786 74.992  144.581 1.00 175.53 ? 349 ASP A OD1 1 
ATOM   1480  O  OD2 . ASP A 1 350 ? 104.084 73.047  145.275 1.00 243.13 ? 349 ASP A OD2 1 
ATOM   1481  N  N   . ILE A 1 351 ? 109.820 73.954  143.496 1.00 70.91  ? 350 ILE A N   1 
ATOM   1482  C  CA  . ILE A 1 351 ? 111.157 73.368  143.578 1.00 113.76 ? 350 ILE A CA  1 
ATOM   1483  C  C   . ILE A 1 351 ? 111.982 73.763  144.837 1.00 128.05 ? 350 ILE A C   1 
ATOM   1484  O  O   . ILE A 1 351 ? 113.015 73.175  145.107 1.00 161.90 ? 350 ILE A O   1 
ATOM   1485  C  CB  . ILE A 1 351 ? 111.919 73.636  142.274 1.00 114.95 ? 350 ILE A CB  1 
ATOM   1486  C  CG1 . ILE A 1 351 ? 112.136 75.150  142.129 1.00 116.31 ? 350 ILE A CG1 1 
ATOM   1487  C  CG2 . ILE A 1 351 ? 111.206 72.913  141.103 1.00 85.84  ? 350 ILE A CG2 1 
ATOM   1488  C  CD1 . ILE A 1 351 ? 113.038 75.516  141.045 1.00 154.90 ? 350 ILE A CD1 1 
ATOM   1489  N  N   . GLU A 1 352 ? 111.552 74.709  145.659 1.00 143.41 ? 351 GLU A N   1 
ATOM   1490  C  CA  . GLU A 1 352 ? 112.106 74.882  146.998 1.00 174.37 ? 351 GLU A CA  1 
ATOM   1491  C  C   . GLU A 1 352 ? 111.762 73.716  147.942 1.00 158.25 ? 351 GLU A C   1 
ATOM   1492  O  O   . GLU A 1 352 ? 112.461 73.543  148.940 1.00 228.77 ? 351 GLU A O   1 
ATOM   1493  C  CB  . GLU A 1 352 ? 111.637 76.222  147.598 1.00 237.60 ? 351 GLU A CB  1 
ATOM   1494  C  CG  . GLU A 1 352 ? 110.142 76.310  147.959 1.00 241.91 ? 351 GLU A CG  1 
ATOM   1495  C  CD  . GLU A 1 352 ? 109.156 76.419  146.803 1.00 234.79 ? 351 GLU A CD  1 
ATOM   1496  O  OE1 . GLU A 1 352 ? 109.621 76.767  145.664 1.00 341.05 ? 351 GLU A OE1 1 
ATOM   1497  O  OE2 . GLU A 1 352 ? 107.934 76.158  147.025 1.00 170.65 ? 351 GLU A OE2 1 
ATOM   1498  N  N   . ASN A 1 353 ? 110.699 72.939  147.666 1.00 129.28 ? 352 ASN A N   1 
ATOM   1499  C  CA  . ASN A 1 353 ? 110.339 71.738  148.422 1.00 158.19 ? 352 ASN A CA  1 
ATOM   1500  C  C   . ASN A 1 353 ? 111.005 70.462  147.873 1.00 160.18 ? 352 ASN A C   1 
ATOM   1501  O  O   . ASN A 1 353 ? 110.765 69.370  148.384 1.00 177.87 ? 352 ASN A O   1 
ATOM   1502  C  CB  . ASN A 1 353 ? 108.815 71.559  148.470 1.00 184.91 ? 352 ASN A CB  1 
ATOM   1503  C  CG  . ASN A 1 353 ? 108.050 72.441  149.438 1.00 209.40 ? 352 ASN A CG  1 
ATOM   1504  O  OD1 . ASN A 1 353 ? 106.831 72.306  149.554 1.00 223.31 ? 352 ASN A OD1 1 
ATOM   1505  N  ND2 . ASN A 1 353 ? 108.724 73.311  150.163 1.00 233.34 ? 352 ASN A ND2 1 
ATOM   1506  N  N   . LEU A 1 354 ? 111.860 70.595  146.850 1.00 157.12 ? 353 LEU A N   1 
ATOM   1507  C  CA  . LEU A 1 354 ? 112.582 69.478  146.278 1.00 161.96 ? 353 LEU A CA  1 
ATOM   1508  C  C   . LEU A 1 354 ? 114.049 69.522  146.747 1.00 186.36 ? 353 LEU A C   1 
ATOM   1509  O  O   . LEU A 1 354 ? 114.755 70.512  146.537 1.00 146.16 ? 353 LEU A O   1 
ATOM   1510  C  CB  . LEU A 1 354 ? 112.425 69.614  144.762 1.00 130.67 ? 353 LEU A CB  1 
ATOM   1511  C  CG  . LEU A 1 354 ? 113.130 68.562  143.917 1.00 158.09 ? 353 LEU A CG  1 
ATOM   1512  C  CD1 . LEU A 1 354 ? 112.509 67.196  144.102 1.00 177.67 ? 353 LEU A CD1 1 
ATOM   1513  C  CD2 . LEU A 1 354 ? 113.112 68.953  142.462 1.00 161.10 ? 353 LEU A CD2 1 
ATOM   1514  N  N   . LYS A 1 355 ? 114.528 68.441  147.386 1.00 208.87 ? 354 LYS A N   1 
ATOM   1515  C  CA  . LYS A 1 355 ? 115.937 68.333  147.753 1.00 250.06 ? 354 LYS A CA  1 
ATOM   1516  C  C   . LYS A 1 355 ? 116.799 68.192  146.489 1.00 225.98 ? 354 LYS A C   1 
ATOM   1517  O  O   . LYS A 1 355 ? 116.388 67.517  145.554 1.00 154.73 ? 354 LYS A O   1 
ATOM   1518  C  CB  . LYS A 1 355 ? 116.154 67.139  148.691 1.00 317.45 ? 354 LYS A CB  1 
ATOM   1519  C  CG  . LYS A 1 355 ? 117.573 67.001  149.234 1.00 386.08 ? 354 LYS A CG  1 
ATOM   1520  C  CD  . LYS A 1 355 ? 117.752 65.947  150.321 1.00 405.06 ? 354 LYS A CD  1 
ATOM   1521  C  CE  . LYS A 1 355 ? 117.639 64.510  149.847 1.00 425.58 ? 354 LYS A CE  1 
ATOM   1522  N  NZ  . LYS A 1 355 ? 118.783 64.073  149.006 1.00 426.88 ? 354 LYS A NZ  1 
ATOM   1523  N  N   . ASP A 1 356 ? 117.992 68.823  146.466 1.00 219.43 ? 355 ASP A N   1 
ATOM   1524  C  CA  . ASP A 1 356 ? 118.952 68.714  145.365 1.00 221.57 ? 355 ASP A CA  1 
ATOM   1525  C  C   . ASP A 1 356 ? 118.329 69.197  144.049 1.00 179.30 ? 355 ASP A C   1 
ATOM   1526  O  O   . ASP A 1 356 ? 118.572 68.627  142.978 1.00 153.18 ? 355 ASP A O   1 
ATOM   1527  C  CB  . ASP A 1 356 ? 119.516 67.285  145.241 1.00 285.13 ? 355 ASP A CB  1 
ATOM   1528  C  CG  . ASP A 1 356 ? 120.803 67.136  144.433 1.00 361.57 ? 355 ASP A CG  1 
ATOM   1529  O  OD1 . ASP A 1 356 ? 121.401 68.166  144.047 1.00 447.21 ? 355 ASP A OD1 1 
ATOM   1530  O  OD2 . ASP A 1 356 ? 121.210 65.977  144.192 1.00 372.20 ? 355 ASP A OD2 1 
ATOM   1531  N  N   . ALA A 1 357 ? 117.541 70.281  144.137 1.00 179.81 ? 356 ALA A N   1 
ATOM   1532  C  CA  . ALA A 1 357 ? 116.648 70.725  143.071 1.00 174.76 ? 356 ALA A CA  1 
ATOM   1533  C  C   . ALA A 1 357 ? 117.378 70.912  141.751 1.00 150.87 ? 356 ALA A C   1 
ATOM   1534  O  O   . ALA A 1 357 ? 116.934 70.378  140.733 1.00 145.17 ? 356 ALA A O   1 
ATOM   1535  C  CB  . ALA A 1 357 ? 116.016 72.022  143.475 1.00 217.00 ? 356 ALA A CB  1 
ATOM   1536  N  N   . SER A 1 358 ? 118.485 71.675  141.793 1.00 147.11 ? 357 SER A N   1 
ATOM   1537  C  CA  . SER A 1 358 ? 119.259 72.014  140.604 1.00 198.12 ? 357 SER A CA  1 
ATOM   1538  C  C   . SER A 1 358 ? 119.674 70.774  139.781 1.00 166.40 ? 357 SER A C   1 
ATOM   1539  O  O   . SER A 1 358 ? 119.663 70.830  138.542 1.00 156.77 ? 357 SER A O   1 
ATOM   1540  C  CB  . SER A 1 358 ? 120.436 72.880  140.985 1.00 199.90 ? 357 SER A CB  1 
ATOM   1541  O  OG  . SER A 1 358 ? 121.272 72.224  141.919 1.00 203.95 ? 357 SER A OG  1 
ATOM   1542  N  N   . SER A 1 359 ? 120.022 69.672  140.464 1.00 150.38 ? 358 SER A N   1 
ATOM   1543  C  CA  . SER A 1 359 ? 120.504 68.461  139.822 1.00 190.07 ? 358 SER A CA  1 
ATOM   1544  C  C   . SER A 1 359 ? 119.375 67.741  139.095 1.00 179.51 ? 358 SER A C   1 
ATOM   1545  O  O   . SER A 1 359 ? 119.576 67.279  137.972 1.00 173.19 ? 358 SER A O   1 
ATOM   1546  C  CB  . SER A 1 359 ? 121.156 67.536  140.819 1.00 249.99 ? 358 SER A CB  1 
ATOM   1547  O  OG  . SER A 1 359 ? 122.198 68.195  141.518 1.00 281.37 ? 358 SER A OG  1 
ATOM   1548  N  N   . PHE A 1 360 ? 118.201 67.641  139.735 1.00 176.89 ? 359 PHE A N   1 
ATOM   1549  C  CA  . PHE A 1 360 ? 117.045 67.010  139.110 1.00 181.40 ? 359 PHE A CA  1 
ATOM   1550  C  C   . PHE A 1 360 ? 116.558 67.840  137.929 1.00 148.02 ? 359 PHE A C   1 
ATOM   1551  O  O   . PHE A 1 360 ? 116.237 67.272  136.896 1.00 115.65 ? 359 PHE A O   1 
ATOM   1552  C  CB  . PHE A 1 360 ? 115.918 66.774  140.116 1.00 159.98 ? 359 PHE A CB  1 
ATOM   1553  C  CG  . PHE A 1 360 ? 116.212 65.761  141.194 1.00 182.89 ? 359 PHE A CG  1 
ATOM   1554  C  CD1 . PHE A 1 360 ? 116.827 64.547  140.899 1.00 209.09 ? 359 PHE A CD1 1 
ATOM   1555  C  CD2 . PHE A 1 360 ? 115.854 66.018  142.522 1.00 209.97 ? 359 PHE A CD2 1 
ATOM   1556  C  CE1 . PHE A 1 360 ? 117.090 63.630  141.907 1.00 280.45 ? 359 PHE A CE1 1 
ATOM   1557  C  CE2 . PHE A 1 360 ? 116.128 65.099  143.530 1.00 169.95 ? 359 PHE A CE2 1 
ATOM   1558  C  CZ  . PHE A 1 360 ? 116.741 63.907  143.218 1.00 254.19 ? 359 PHE A CZ  1 
ATOM   1559  N  N   . LEU A 1 361 ? 116.525 69.166  138.056 1.00 142.90 ? 360 LEU A N   1 
ATOM   1560  C  CA  . LEU A 1 361 ? 116.175 70.002  136.915 1.00 146.65 ? 360 LEU A CA  1 
ATOM   1561  C  C   . LEU A 1 361 ? 117.171 69.787  135.777 1.00 134.47 ? 360 LEU A C   1 
ATOM   1562  O  O   . LEU A 1 361 ? 116.744 69.691  134.628 1.00 147.55 ? 360 LEU A O   1 
ATOM   1563  C  CB  . LEU A 1 361 ? 116.117 71.482  137.306 1.00 142.98 ? 360 LEU A CB  1 
ATOM   1564  C  CG  . LEU A 1 361 ? 115.020 71.926  138.286 1.00 141.13 ? 360 LEU A CG  1 
ATOM   1565  C  CD1 . LEU A 1 361 ? 115.074 73.434  138.439 1.00 158.20 ? 360 LEU A CD1 1 
ATOM   1566  C  CD2 . LEU A 1 361 ? 113.610 71.524  137.886 1.00 119.31 ? 360 LEU A CD2 1 
ATOM   1567  N  N   . ALA A 1 362 ? 118.470 69.702  136.083 1.00 121.79 ? 361 ALA A N   1 
ATOM   1568  C  CA  . ALA A 1 362 ? 119.467 69.479  135.047 1.00 162.39 ? 361 ALA A CA  1 
ATOM   1569  C  C   . ALA A 1 362 ? 119.252 68.145  134.326 1.00 160.86 ? 361 ALA A C   1 
ATOM   1570  O  O   . ALA A 1 362 ? 119.434 68.084  133.108 1.00 154.03 ? 361 ALA A O   1 
ATOM   1571  C  CB  . ALA A 1 362 ? 120.853 69.597  135.639 1.00 218.10 ? 361 ALA A CB  1 
ATOM   1572  N  N   . GLU A 1 363 ? 118.859 67.095  135.064 1.00 156.96 ? 362 GLU A N   1 
ATOM   1573  C  CA  . GLU A 1 363 ? 118.601 65.785  134.483 1.00 187.67 ? 362 GLU A CA  1 
ATOM   1574  C  C   . GLU A 1 363 ? 117.372 65.853  133.569 1.00 163.26 ? 362 GLU A C   1 
ATOM   1575  O  O   . GLU A 1 363 ? 117.449 65.410  132.424 1.00 142.72 ? 362 GLU A O   1 
ATOM   1576  C  CB  . GLU A 1 363 ? 118.461 64.758  135.611 1.00 265.94 ? 362 GLU A CB  1 
ATOM   1577  C  CG  . GLU A 1 363 ? 118.187 63.344  135.132 1.00 331.54 ? 362 GLU A CG  1 
ATOM   1578  C  CD  . GLU A 1 363 ? 118.217 62.273  136.211 1.00 383.30 ? 362 GLU A CD  1 
ATOM   1579  O  OE1 . GLU A 1 363 ? 117.671 62.521  137.317 1.00 338.22 ? 362 GLU A OE1 1 
ATOM   1580  O  OE2 . GLU A 1 363 ? 118.781 61.187  135.946 1.00 464.63 ? 362 GLU A OE2 1 
ATOM   1581  N  N   . TRP A 1 364 ? 116.256 66.401  134.070 1.00 126.65 ? 363 TRP A N   1 
ATOM   1582  C  CA  . TRP A 1 364 ? 115.004 66.494  133.326 1.00 122.93 ? 363 TRP A CA  1 
ATOM   1583  C  C   . TRP A 1 364 ? 115.120 67.392  132.093 1.00 133.32 ? 363 TRP A C   1 
ATOM   1584  O  O   . TRP A 1 364 ? 114.512 67.124  131.055 1.00 111.74 ? 363 TRP A O   1 
ATOM   1585  C  CB  . TRP A 1 364 ? 113.908 67.031  134.251 1.00 126.26 ? 363 TRP A CB  1 
ATOM   1586  C  CG  . TRP A 1 364 ? 113.665 66.191  135.467 1.00 115.42 ? 363 TRP A CG  1 
ATOM   1587  C  CD1 . TRP A 1 364 ? 113.940 64.870  135.581 1.00 145.45 ? 363 TRP A CD1 1 
ATOM   1588  C  CD2 . TRP A 1 364 ? 113.111 66.605  136.732 1.00 99.74  ? 363 TRP A CD2 1 
ATOM   1589  N  NE1 . TRP A 1 364 ? 113.598 64.447  136.830 1.00 174.55 ? 363 TRP A NE1 1 
ATOM   1590  C  CE2 . TRP A 1 364 ? 113.080 65.486  137.557 1.00 119.88 ? 363 TRP A CE2 1 
ATOM   1591  C  CE3 . TRP A 1 364 ? 112.639 67.798  137.255 1.00 119.03 ? 363 TRP A CE3 1 
ATOM   1592  C  CZ2 . TRP A 1 364 ? 112.603 65.529  138.867 1.00 162.73 ? 363 TRP A CZ2 1 
ATOM   1593  C  CZ3 . TRP A 1 364 ? 112.162 67.838  138.543 1.00 152.22 ? 363 TRP A CZ3 1 
ATOM   1594  C  CH2 . TRP A 1 364 ? 112.131 66.717  139.349 1.00 140.53 ? 363 TRP A CH2 1 
ATOM   1595  N  N   . GLN A 1 365 ? 115.900 68.469  132.221 1.00 134.42 ? 364 GLN A N   1 
ATOM   1596  C  CA  . GLN A 1 365 ? 116.200 69.348  131.102 1.00 141.49 ? 364 GLN A CA  1 
ATOM   1597  C  C   . GLN A 1 365 ? 116.999 68.574  130.050 1.00 128.08 ? 364 GLN A C   1 
ATOM   1598  O  O   . GLN A 1 365 ? 116.658 68.641  128.878 1.00 146.19 ? 364 GLN A O   1 
ATOM   1599  C  CB  . GLN A 1 365 ? 116.890 70.597  131.645 1.00 148.38 ? 364 GLN A CB  1 
ATOM   1600  C  CG  . GLN A 1 365 ? 117.389 71.560  130.583 1.00 158.20 ? 364 GLN A CG  1 
ATOM   1601  C  CD  . GLN A 1 365 ? 116.315 72.383  129.928 1.00 184.41 ? 364 GLN A CD  1 
ATOM   1602  O  OE1 . GLN A 1 365 ? 115.126 72.077  129.966 1.00 186.68 ? 364 GLN A OE1 1 
ATOM   1603  N  NE2 . GLN A 1 365 ? 116.749 73.463  129.302 1.00 246.72 ? 364 GLN A NE2 1 
ATOM   1604  N  N   . ASN A 1 366 ? 118.037 67.841  130.459 1.00 147.61 ? 365 ASN A N   1 
ATOM   1605  C  CA  . ASN A 1 366 ? 118.799 67.006  129.543 1.00 191.67 ? 365 ASN A CA  1 
ATOM   1606  C  C   . ASN A 1 366 ? 117.890 66.003  128.845 1.00 160.76 ? 365 ASN A C   1 
ATOM   1607  O  O   . ASN A 1 366 ? 118.009 65.846  127.627 1.00 216.27 ? 365 ASN A O   1 
ATOM   1608  C  CB  . ASN A 1 366 ? 119.984 66.303  130.219 1.00 265.63 ? 365 ASN A CB  1 
ATOM   1609  C  CG  . ASN A 1 366 ? 121.299 66.954  129.851 1.00 326.00 ? 365 ASN A CG  1 
ATOM   1610  O  OD1 . ASN A 1 366 ? 121.509 68.122  130.171 1.00 337.05 ? 365 ASN A OD1 1 
ATOM   1611  N  ND2 . ASN A 1 366 ? 122.168 66.211  129.176 1.00 356.88 ? 365 ASN A ND2 1 
ATOM   1612  N  N   . ILE A 1 367 ? 116.997 65.341  129.594 1.00 124.01 ? 366 ILE A N   1 
ATOM   1613  C  CA  . ILE A 1 367 ? 116.066 64.390  128.998 1.00 163.60 ? 366 ILE A CA  1 
ATOM   1614  C  C   . ILE A 1 367 ? 115.210 65.069  127.924 1.00 143.84 ? 366 ILE A C   1 
ATOM   1615  O  O   . ILE A 1 367 ? 115.010 64.490  126.844 1.00 118.42 ? 366 ILE A O   1 
ATOM   1616  C  CB  . ILE A 1 367 ? 115.226 63.695  130.085 1.00 187.13 ? 366 ILE A CB  1 
ATOM   1617  C  CG1 . ILE A 1 367 ? 116.122 62.786  130.933 1.00 250.43 ? 366 ILE A CG1 1 
ATOM   1618  C  CG2 . ILE A 1 367 ? 114.038 62.925  129.497 1.00 213.77 ? 366 ILE A CG2 1 
ATOM   1619  C  CD1 . ILE A 1 367 ? 115.569 62.450  132.301 1.00 301.15 ? 366 ILE A CD1 1 
ATOM   1620  N  N   . THR A 1 368 ? 114.726 66.283  128.228 1.00 133.43 ? 367 THR A N   1 
ATOM   1621  C  CA  . THR A 1 368 ? 113.825 67.003  127.336 1.00 167.18 ? 367 THR A CA  1 
ATOM   1622  C  C   . THR A 1 368 ? 114.572 67.476  126.085 1.00 157.43 ? 367 THR A C   1 
ATOM   1623  O  O   . THR A 1 368 ? 114.185 67.109  124.985 1.00 213.09 ? 367 THR A O   1 
ATOM   1624  C  CB  . THR A 1 368 ? 113.085 68.143  128.054 1.00 171.32 ? 367 THR A CB  1 
ATOM   1625  O  OG1 . THR A 1 368 ? 112.437 67.544  129.200 1.00 110.24 ? 367 THR A OG1 1 
ATOM   1626  C  CG2 . THR A 1 368 ? 112.153 68.899  127.105 1.00 137.69 ? 367 THR A CG2 1 
ATOM   1627  N  N   . LYS A 1 369 ? 115.631 68.273  126.226 1.00 155.13 ? 368 LYS A N   1 
ATOM   1628  C  CA  . LYS A 1 369 ? 116.364 68.772  125.071 1.00 187.10 ? 368 LYS A CA  1 
ATOM   1629  C  C   . LYS A 1 369 ? 117.006 67.635  124.269 1.00 190.09 ? 368 LYS A C   1 
ATOM   1630  O  O   . LYS A 1 369 ? 117.144 67.750  123.051 1.00 144.71 ? 368 LYS A O   1 
ATOM   1631  C  CB  . LYS A 1 369 ? 117.420 69.765  125.554 1.00 250.34 ? 368 LYS A CB  1 
ATOM   1632  C  CG  . LYS A 1 369 ? 116.853 71.112  125.963 1.00 209.01 ? 368 LYS A CG  1 
ATOM   1633  C  CD  . LYS A 1 369 ? 116.535 71.949  124.764 1.00 266.95 ? 368 LYS A CD  1 
ATOM   1634  C  CE  . LYS A 1 369 ? 116.215 73.384  125.114 1.00 354.70 ? 368 LYS A CE  1 
ATOM   1635  N  NZ  . LYS A 1 369 ? 116.222 74.267  123.919 1.00 379.67 ? 368 LYS A NZ  1 
ATOM   1636  N  N   . GLY A 1 370 ? 117.395 66.550  124.955 1.00 241.14 ? 369 GLY A N   1 
ATOM   1637  C  CA  . GLY A 1 370 ? 117.885 65.336  124.319 1.00 287.23 ? 369 GLY A CA  1 
ATOM   1638  C  C   . GLY A 1 370 ? 116.840 64.622  123.466 1.00 248.85 ? 369 GLY A C   1 
ATOM   1639  O  O   . GLY A 1 370 ? 117.223 63.868  122.572 1.00 334.58 ? 369 GLY A O   1 
ATOM   1640  N  N   . PHE A 1 371 ? 115.544 64.846  123.735 1.00 150.42 ? 370 PHE A N   1 
ATOM   1641  C  CA  . PHE A 1 371 ? 114.502 64.376  122.836 1.00 170.39 ? 370 PHE A CA  1 
ATOM   1642  C  C   . PHE A 1 371 ? 114.420 65.245  121.578 1.00 158.65 ? 370 PHE A C   1 
ATOM   1643  O  O   . PHE A 1 371 ? 114.525 64.729  120.465 1.00 228.26 ? 370 PHE A O   1 
ATOM   1644  C  CB  . PHE A 1 371 ? 113.155 64.321  123.544 1.00 164.86 ? 370 PHE A CB  1 
ATOM   1645  C  CG  . PHE A 1 371 ? 112.152 63.471  122.816 1.00 170.73 ? 370 PHE A CG  1 
ATOM   1646  C  CD1 . PHE A 1 371 ? 111.461 63.961  121.709 1.00 150.82 ? 370 PHE A CD1 1 
ATOM   1647  C  CD2 . PHE A 1 371 ? 111.914 62.168  123.242 1.00 213.62 ? 370 PHE A CD2 1 
ATOM   1648  C  CE1 . PHE A 1 371 ? 110.541 63.161  121.043 1.00 227.00 ? 370 PHE A CE1 1 
ATOM   1649  C  CE2 . PHE A 1 371 ? 110.993 61.371  122.576 1.00 276.84 ? 370 PHE A CE2 1 
ATOM   1650  C  CZ  . PHE A 1 371 ? 110.308 61.866  121.478 1.00 293.72 ? 370 PHE A CZ  1 
ATOM   1651  N  N   . SER A 1 372 ? 114.219 66.551  121.760 1.00 134.89 ? 371 SER A N   1 
ATOM   1652  C  CA  . SER A 1 372 ? 114.186 67.504  120.659 1.00 180.97 ? 371 SER A CA  1 
ATOM   1653  C  C   . SER A 1 372 ? 114.443 68.916  121.178 1.00 193.21 ? 371 SER A C   1 
ATOM   1654  O  O   . SER A 1 372 ? 114.208 69.210  122.343 1.00 257.48 ? 371 SER A O   1 
ATOM   1655  C  CB  . SER A 1 372 ? 112.867 67.414  119.886 1.00 196.09 ? 371 SER A CB  1 
ATOM   1656  O  OG  . SER A 1 372 ? 112.721 68.398  118.855 1.00 148.16 ? 371 SER A OG  1 
ATOM   1657  N  N   . GLU A 1 373 ? 114.906 69.796  120.286 1.00 190.13 ? 372 GLU A N   1 
ATOM   1658  C  CA  . GLU A 1 373 ? 115.296 71.153  120.655 1.00 216.67 ? 372 GLU A CA  1 
ATOM   1659  C  C   . GLU A 1 373 ? 114.064 72.044  120.907 1.00 182.27 ? 372 GLU A C   1 
ATOM   1660  O  O   . GLU A 1 373 ? 114.183 73.032  121.644 1.00 197.25 ? 372 GLU A O   1 
ATOM   1661  C  CB  . GLU A 1 373 ? 116.267 71.732  119.616 1.00 277.55 ? 372 GLU A CB  1 
ATOM   1662  C  CG  . GLU A 1 373 ? 115.781 71.707  118.162 1.00 387.10 ? 372 GLU A CG  1 
ATOM   1663  C  CD  . GLU A 1 373 ? 116.735 72.341  117.159 1.00 491.43 ? 372 GLU A CD  1 
ATOM   1664  O  OE1 . GLU A 1 373 ? 117.150 73.495  117.397 1.00 564.06 ? 372 GLU A OE1 1 
ATOM   1665  O  OE2 . GLU A 1 373 ? 117.062 71.685  116.138 1.00 537.22 ? 372 GLU A OE2 1 
ATOM   1666  N  N   . ASP A 1 374 ? 112.891 71.708  120.325 1.00 118.80 ? 373 ASP A N   1 
ATOM   1667  C  CA  . ASP A 1 374 ? 111.669 72.494  120.469 1.00 113.64 ? 373 ASP A CA  1 
ATOM   1668  C  C   . ASP A 1 374 ? 110.728 71.996  121.577 1.00 117.06 ? 373 ASP A C   1 
ATOM   1669  O  O   . ASP A 1 374 ? 109.490 72.019  121.391 1.00 108.59 ? 373 ASP A O   1 
ATOM   1670  C  CB  . ASP A 1 374 ? 110.987 72.644  119.088 1.00 167.01 ? 373 ASP A CB  1 
ATOM   1671  C  CG  . ASP A 1 374 ? 111.552 73.815  118.256 1.00 249.53 ? 373 ASP A CG  1 
ATOM   1672  O  OD1 . ASP A 1 374 ? 112.815 73.982  118.249 1.00 295.95 ? 373 ASP A OD1 1 
ATOM   1673  O  OD2 . ASP A 1 374 ? 110.750 74.591  117.617 1.00 220.46 ? 373 ASP A OD2 1 
ATOM   1674  N  N   . ARG A 1 375 ? 111.288 71.579  122.732 1.00 139.24 ? 374 ARG A N   1 
ATOM   1675  C  CA  . ARG A 1 375 ? 110.517 71.246  123.934 1.00 148.25 ? 374 ARG A CA  1 
ATOM   1676  C  C   . ARG A 1 375 ? 111.135 71.926  125.141 1.00 130.40 ? 374 ARG A C   1 
ATOM   1677  O  O   . ARG A 1 375 ? 112.368 72.053  125.184 1.00 168.92 ? 374 ARG A O   1 
ATOM   1678  C  CB  . ARG A 1 375 ? 110.409 69.728  124.178 1.00 118.80 ? 374 ARG A CB  1 
ATOM   1679  C  CG  . ARG A 1 375 ? 109.377 69.075  123.269 1.00 165.14 ? 374 ARG A CG  1 
ATOM   1680  C  CD  . ARG A 1 375 ? 109.951 68.408  122.043 1.00 159.96 ? 374 ARG A CD  1 
ATOM   1681  N  NE  . ARG A 1 375 ? 108.986 68.275  120.940 1.00 188.10 ? 374 ARG A NE  1 
ATOM   1682  C  CZ  . ARG A 1 375 ? 108.084 67.308  120.769 1.00 235.44 ? 374 ARG A CZ  1 
ATOM   1683  N  NH1 . ARG A 1 375 ? 107.224 67.376  119.763 1.00 262.05 ? 374 ARG A NH1 1 
ATOM   1684  N  NH2 . ARG A 1 375 ? 108.024 66.275  121.593 1.00 164.62 ? 374 ARG A NH2 1 
ATOM   1685  N  N   . LEU A 1 376 ? 110.270 72.325  126.115 1.00 84.82  ? 375 LEU A N   1 
ATOM   1686  C  CA  . LEU A 1 376 ? 110.801 73.053  127.281 1.00 115.21 ? 375 LEU A CA  1 
ATOM   1687  C  C   . LEU A 1 376 ? 110.308 72.519  128.611 1.00 81.02  ? 375 LEU A C   1 
ATOM   1688  O  O   . LEU A 1 376 ? 109.241 71.932  128.688 1.00 68.97  ? 375 LEU A O   1 
ATOM   1689  C  CB  . LEU A 1 376 ? 110.574 74.569  127.295 1.00 102.13 ? 375 LEU A CB  1 
ATOM   1690  C  CG  . LEU A 1 376 ? 109.213 75.049  127.736 1.00 99.17  ? 375 LEU A CG  1 
ATOM   1691  C  CD1 . LEU A 1 376 ? 109.134 76.552  127.815 1.00 123.43 ? 375 LEU A CD1 1 
ATOM   1692  C  CD2 . LEU A 1 376 ? 108.228 74.560  126.740 1.00 126.33 ? 375 LEU A CD2 1 
ATOM   1693  N  N   . LEU A 1 377 ? 111.146 72.784  129.615 1.00 82.92  ? 376 LEU A N   1 
ATOM   1694  C  CA  . LEU A 1 377 ? 110.793 72.554  130.988 1.00 98.53  ? 376 LEU A CA  1 
ATOM   1695  C  C   . LEU A 1 377 ? 110.677 73.937  131.694 1.00 94.78  ? 376 LEU A C   1 
ATOM   1696  O  O   . LEU A 1 377 ? 111.620 74.687  131.804 1.00 99.05  ? 376 LEU A O   1 
ATOM   1697  C  CB  . LEU A 1 377 ? 111.805 71.531  131.522 1.00 90.10  ? 376 LEU A CB  1 
ATOM   1698  C  CG  . LEU A 1 377 ? 111.768 71.314  133.034 1.00 135.94 ? 376 LEU A CG  1 
ATOM   1699  C  CD1 . LEU A 1 377 ? 110.561 70.484  133.450 1.00 147.55 ? 376 LEU A CD1 1 
ATOM   1700  C  CD2 . LEU A 1 377 ? 113.058 70.661  133.519 1.00 175.46 ? 376 LEU A CD2 1 
ATOM   1701  N  N   . ILE A 1 378 ? 109.471 74.271  132.163 1.00 96.29  ? 377 ILE A N   1 
ATOM   1702  C  CA  . ILE A 1 378 ? 109.148 75.420  132.979 1.00 73.61  ? 377 ILE A CA  1 
ATOM   1703  C  C   . ILE A 1 378 ? 109.224 75.021  134.453 1.00 81.91  ? 377 ILE A C   1 
ATOM   1704  O  O   . ILE A 1 378 ? 108.311 74.435  135.009 1.00 85.09  ? 377 ILE A O   1 
ATOM   1705  C  CB  . ILE A 1 378 ? 107.713 75.863  132.659 1.00 84.88  ? 377 ILE A CB  1 
ATOM   1706  C  CG1 . ILE A 1 378 ? 107.602 76.233  131.205 1.00 86.15  ? 377 ILE A CG1 1 
ATOM   1707  C  CG2 . ILE A 1 378 ? 107.254 77.028  133.499 1.00 134.38 ? 377 ILE A CG2 1 
ATOM   1708  C  CD1 . ILE A 1 378 ? 106.247 76.730  130.851 1.00 115.37 ? 377 ILE A CD1 1 
ATOM   1709  N  N   . ALA A 1 379 ? 110.301 75.358  135.128 1.00 75.66  ? 378 ALA A N   1 
ATOM   1710  C  CA  . ALA A 1 379 ? 110.294 75.264  136.579 1.00 80.06  ? 378 ALA A CA  1 
ATOM   1711  C  C   . ALA A 1 379 ? 109.500 76.401  137.228 1.00 73.83  ? 378 ALA A C   1 
ATOM   1712  O  O   . ALA A 1 379 ? 109.248 77.423  136.646 1.00 102.82 ? 378 ALA A O   1 
ATOM   1713  C  CB  . ALA A 1 379 ? 111.698 75.249  137.071 1.00 107.32 ? 378 ALA A CB  1 
ATOM   1714  N  N   . GLY A 1 380 ? 109.071 76.215  138.463 1.00 103.27 ? 379 GLY A N   1 
ATOM   1715  C  CA  . GLY A 1 380 ? 108.427 77.281  139.220 1.00 100.63 ? 379 GLY A CA  1 
ATOM   1716  C  C   . GLY A 1 380 ? 108.748 77.157  140.701 1.00 99.32  ? 379 GLY A C   1 
ATOM   1717  O  O   . GLY A 1 380 ? 108.837 76.043  141.203 1.00 131.87 ? 379 GLY A O   1 
ATOM   1718  N  N   . THR A 1 381 ? 108.924 78.289  141.375 1.00 85.84  ? 380 THR A N   1 
ATOM   1719  C  CA  . THR A 1 381 ? 109.226 78.301  142.792 1.00 76.33  ? 380 THR A CA  1 
ATOM   1720  C  C   . THR A 1 381 ? 108.390 79.319  143.539 1.00 86.96  ? 380 THR A C   1 
ATOM   1721  O  O   . THR A 1 381 ? 107.961 80.309  142.948 1.00 167.77 ? 380 THR A O   1 
ATOM   1722  C  CB  . THR A 1 381 ? 110.684 78.648  143.027 1.00 94.64  ? 380 THR A CB  1 
ATOM   1723  O  OG1 . THR A 1 381 ? 110.868 78.751  144.446 1.00 141.35 ? 380 THR A OG1 1 
ATOM   1724  C  CG2 . THR A 1 381 ? 111.116 79.944  142.388 1.00 96.57  ? 380 THR A CG2 1 
ATOM   1725  N  N   . ASN A 1 382 ? 108.141 79.079  144.836 1.00 84.18  ? 381 ASN A N   1 
ATOM   1726  C  CA  . ASN A 1 382 ? 107.438 80.052  145.657 1.00 108.93 ? 381 ASN A CA  1 
ATOM   1727  C  C   . ASN A 1 382 ? 108.359 81.231  145.997 1.00 117.72 ? 381 ASN A C   1 
ATOM   1728  O  O   . ASN A 1 382 ? 107.846 82.270  146.469 1.00 173.31 ? 381 ASN A O   1 
ATOM   1729  C  CB  . ASN A 1 382 ? 106.803 79.393  146.870 1.00 134.39 ? 381 ASN A CB  1 
ATOM   1730  C  CG  . ASN A 1 382 ? 107.794 79.222  148.000 1.00 238.38 ? 381 ASN A CG  1 
ATOM   1731  O  OD1 . ASN A 1 382 ? 109.016 79.239  147.798 1.00 179.13 ? 381 ASN A OD1 1 
ATOM   1732  N  ND2 . ASN A 1 382 ? 107.237 79.062  149.192 1.00 303.80 ? 381 ASN A ND2 1 
ATOM   1733  N  N   . SER A 1 383 ? 109.678 81.089  145.730 1.00 85.35  ? 382 SER A N   1 
ATOM   1734  C  CA  . SER A 1 383 ? 110.674 82.110  146.070 1.00 124.48 ? 382 SER A CA  1 
ATOM   1735  C  C   . SER A 1 383 ? 110.441 83.528  145.523 1.00 127.26 ? 382 SER A C   1 
ATOM   1736  O  O   . SER A 1 383 ? 109.897 83.676  144.430 1.00 119.82 ? 382 SER A O   1 
ATOM   1737  C  CB  . SER A 1 383 ? 111.988 81.678  145.589 1.00 118.32 ? 382 SER A CB  1 
ATOM   1738  O  OG  . SER A 1 383 ? 112.960 82.520  146.141 1.00 115.33 ? 382 SER A OG  1 
ATOM   1739  N  N   . SER A 1 384 ? 110.876 84.554  146.299 1.00 111.85 ? 383 SER A N   1 
ATOM   1740  C  CA  . SER A 1 384 ? 111.031 85.907  145.785 1.00 123.61 ? 383 SER A CA  1 
ATOM   1741  C  C   . SER A 1 384 ? 112.446 86.471  145.986 1.00 108.45 ? 383 SER A C   1 
ATOM   1742  O  O   . SER A 1 384 ? 112.659 87.682  145.885 1.00 142.72 ? 383 SER A O   1 
ATOM   1743  C  CB  . SER A 1 384 ? 109.977 86.787  146.374 1.00 162.18 ? 383 SER A CB  1 
ATOM   1744  O  OG  . SER A 1 384 ? 110.234 87.158  147.727 1.00 186.68 ? 383 SER A OG  1 
ATOM   1745  N  N   . ASP A 1 385 ? 113.432 85.607  146.226 1.00 119.01 ? 384 ASP A N   1 
ATOM   1746  C  CA  . ASP A 1 385 ? 114.796 86.043  146.469 1.00 155.07 ? 384 ASP A CA  1 
ATOM   1747  C  C   . ASP A 1 385 ? 115.583 86.043  145.167 1.00 128.77 ? 384 ASP A C   1 
ATOM   1748  O  O   . ASP A 1 385 ? 115.738 84.997  144.509 1.00 172.74 ? 384 ASP A O   1 
ATOM   1749  C  CB  . ASP A 1 385 ? 115.497 85.118  147.462 1.00 230.05 ? 384 ASP A CB  1 
ATOM   1750  C  CG  . ASP A 1 385 ? 117.003 85.334  147.533 1.00 299.48 ? 384 ASP A CG  1 
ATOM   1751  O  OD1 . ASP A 1 385 ? 117.466 86.471  147.276 1.00 338.45 ? 384 ASP A OD1 1 
ATOM   1752  O  OD2 . ASP A 1 385 ? 117.720 84.358  147.817 1.00 297.81 ? 384 ASP A OD2 1 
ATOM   1753  N  N   . LEU A 1 386 ? 116.135 87.206  144.807 1.00 103.59 ? 385 LEU A N   1 
ATOM   1754  C  CA  . LEU A 1 386 ? 116.879 87.269  143.556 1.00 130.99 ? 385 LEU A CA  1 
ATOM   1755  C  C   . LEU A 1 386 ? 118.028 86.240  143.487 1.00 165.39 ? 385 LEU A C   1 
ATOM   1756  O  O   . LEU A 1 386 ? 118.303 85.671  142.415 1.00 108.97 ? 385 LEU A O   1 
ATOM   1757  C  CB  . LEU A 1 386 ? 117.416 88.690  143.425 1.00 109.73 ? 385 LEU A CB  1 
ATOM   1758  C  CG  . LEU A 1 386 ? 118.349 88.883  142.231 1.00 116.75 ? 385 LEU A CG  1 
ATOM   1759  C  CD1 . LEU A 1 386 ? 117.655 88.465  140.943 1.00 82.49  ? 385 LEU A CD1 1 
ATOM   1760  C  CD2 . LEU A 1 386 ? 118.855 90.330  142.209 1.00 186.32 ? 385 LEU A CD2 1 
ATOM   1761  N  N   . GLN A 1 387 ? 118.722 86.017  144.620 1.00 177.62 ? 386 GLN A N   1 
ATOM   1762  C  CA  . GLN A 1 387 ? 119.914 85.193  144.628 1.00 161.41 ? 386 GLN A CA  1 
ATOM   1763  C  C   . GLN A 1 387 ? 119.533 83.726  144.516 1.00 166.74 ? 386 GLN A C   1 
ATOM   1764  O  O   . GLN A 1 387 ? 120.155 83.006  143.734 1.00 199.89 ? 386 GLN A O   1 
ATOM   1765  C  CB  . GLN A 1 387 ? 120.751 85.486  145.871 1.00 203.99 ? 386 GLN A CB  1 
ATOM   1766  C  CG  . GLN A 1 387 ? 121.367 86.880  145.849 1.00 247.91 ? 386 GLN A CG  1 
ATOM   1767  C  CD  . GLN A 1 387 ? 122.353 87.098  144.720 1.00 319.73 ? 386 GLN A CD  1 
ATOM   1768  O  OE1 . GLN A 1 387 ? 122.822 86.160  144.069 1.00 251.19 ? 386 GLN A OE1 1 
ATOM   1769  N  NE2 . GLN A 1 387 ? 122.684 88.360  144.480 1.00 362.65 ? 386 GLN A NE2 1 
ATOM   1770  N  N   . GLN A 1 388 ? 118.531 83.273  145.278 1.00 129.77 ? 387 GLN A N   1 
ATOM   1771  C  CA  . GLN A 1 388 ? 118.064 81.900  145.155 1.00 165.63 ? 387 GLN A CA  1 
ATOM   1772  C  C   . GLN A 1 388 ? 117.681 81.611  143.692 1.00 150.28 ? 387 GLN A C   1 
ATOM   1773  O  O   . GLN A 1 388 ? 118.109 80.619  143.100 1.00 138.82 ? 387 GLN A O   1 
ATOM   1774  C  CB  . GLN A 1 388 ? 116.949 81.641  146.165 1.00 141.93 ? 387 GLN A CB  1 
ATOM   1775  C  CG  . GLN A 1 388 ? 116.513 80.188  146.200 1.00 196.26 ? 387 GLN A CG  1 
ATOM   1776  C  CD  . GLN A 1 388 ? 115.338 79.929  147.118 1.00 270.65 ? 387 GLN A CD  1 
ATOM   1777  O  OE1 . GLN A 1 388 ? 114.614 80.844  147.515 1.00 327.04 ? 387 GLN A OE1 1 
ATOM   1778  N  NE2 . GLN A 1 388 ? 115.112 78.669  147.448 1.00 285.36 ? 387 GLN A NE2 1 
ATOM   1779  N  N   . ILE A 1 389 ? 116.898 82.490  143.088 1.00 137.61 ? 388 ILE A N   1 
ATOM   1780  C  CA  . ILE A 1 389 ? 116.488 82.321  141.700 1.00 106.94 ? 388 ILE A CA  1 
ATOM   1781  C  C   . ILE A 1 389 ? 117.697 82.320  140.766 1.00 110.02 ? 388 ILE A C   1 
ATOM   1782  O  O   . ILE A 1 389 ? 117.773 81.427  139.922 1.00 179.59 ? 388 ILE A O   1 
ATOM   1783  C  CB  . ILE A 1 389 ? 115.438 83.374  141.337 1.00 89.94  ? 388 ILE A CB  1 
ATOM   1784  C  CG1 . ILE A 1 389 ? 114.134 83.039  142.060 1.00 108.66 ? 388 ILE A CG1 1 
ATOM   1785  C  CG2 . ILE A 1 389 ? 115.247 83.486  139.843 1.00 94.25  ? 388 ILE A CG2 1 
ATOM   1786  C  CD1 . ILE A 1 389 ? 113.231 84.236  142.275 1.00 127.56 ? 388 ILE A CD1 1 
ATOM   1787  N  N   . LEU A 1 390 ? 118.642 83.254  140.912 1.00 106.08 ? 389 LEU A N   1 
ATOM   1788  C  CA  . LEU A 1 390 ? 119.828 83.224  140.071 1.00 133.63 ? 389 LEU A CA  1 
ATOM   1789  C  C   . LEU A 1 390 ? 120.635 81.929  140.244 1.00 148.86 ? 389 LEU A C   1 
ATOM   1790  O  O   . LEU A 1 390 ? 121.278 81.523  139.282 1.00 153.01 ? 389 LEU A O   1 
ATOM   1791  C  CB  . LEU A 1 390 ? 120.682 84.442  140.390 1.00 170.38 ? 389 LEU A CB  1 
ATOM   1792  C  CG  . LEU A 1 390 ? 120.191 85.745  139.765 1.00 175.16 ? 389 LEU A CG  1 
ATOM   1793  C  CD1 . LEU A 1 390 ? 120.780 86.924  140.505 1.00 190.78 ? 389 LEU A CD1 1 
ATOM   1794  C  CD2 . LEU A 1 390 ? 120.572 85.833  138.272 1.00 165.47 ? 389 LEU A CD2 1 
ATOM   1795  N  N   . SER A 1 391 ? 120.613 81.287  141.429 1.00 127.70 ? 390 SER A N   1 
ATOM   1796  C  CA  . SER A 1 391 ? 121.310 80.019  141.638 1.00 187.88 ? 390 SER A CA  1 
ATOM   1797  C  C   . SER A 1 391 ? 120.638 78.850  140.897 1.00 163.72 ? 390 SER A C   1 
ATOM   1798  O  O   . SER A 1 391 ? 121.334 78.025  140.303 1.00 210.55 ? 390 SER A O   1 
ATOM   1799  C  CB  . SER A 1 391 ? 121.497 79.733  143.123 1.00 209.70 ? 390 SER A CB  1 
ATOM   1800  O  OG  . SER A 1 391 ? 120.308 79.276  143.739 1.00 168.83 ? 390 SER A OG  1 
ATOM   1801  N  N   . LEU A 1 392 ? 119.302 78.769  140.921 1.00 126.77 ? 391 LEU A N   1 
ATOM   1802  C  CA  . LEU A 1 392 ? 118.552 77.760  140.150 1.00 131.70 ? 391 LEU A CA  1 
ATOM   1803  C  C   . LEU A 1 392 ? 118.709 77.976  138.636 1.00 130.21 ? 391 LEU A C   1 
ATOM   1804  O  O   . LEU A 1 392 ? 118.711 77.023  137.884 1.00 144.95 ? 391 LEU A O   1 
ATOM   1805  C  CB  . LEU A 1 392 ? 117.065 77.827  140.494 1.00 132.59 ? 391 LEU A CB  1 
ATOM   1806  C  CG  . LEU A 1 392 ? 116.564 77.202  141.797 1.00 181.26 ? 391 LEU A CG  1 
ATOM   1807  C  CD1 . LEU A 1 392 ? 117.645 77.043  142.860 1.00 261.92 ? 391 LEU A CD1 1 
ATOM   1808  C  CD2 . LEU A 1 392 ? 115.364 78.008  142.391 1.00 138.05 ? 391 LEU A CD2 1 
ATOM   1809  N  N   . LEU A 1 393 ? 118.859 79.228  138.192 1.00 129.88 ? 392 LEU A N   1 
ATOM   1810  C  CA  . LEU A 1 393 ? 119.153 79.579  136.813 1.00 145.96 ? 392 LEU A CA  1 
ATOM   1811  C  C   . LEU A 1 393 ? 120.655 79.579  136.464 1.00 213.27 ? 392 LEU A C   1 
ATOM   1812  O  O   . LEU A 1 393 ? 121.023 80.029  135.364 1.00 332.08 ? 392 LEU A O   1 
ATOM   1813  C  CB  . LEU A 1 393 ? 118.613 80.995  136.582 1.00 178.47 ? 392 LEU A CB  1 
ATOM   1814  C  CG  . LEU A 1 393 ? 117.157 81.111  136.193 1.00 175.13 ? 392 LEU A CG  1 
ATOM   1815  C  CD1 . LEU A 1 393 ? 116.635 82.478  136.575 1.00 234.75 ? 392 LEU A CD1 1 
ATOM   1816  C  CD2 . LEU A 1 393 ? 117.007 80.923  134.699 1.00 269.71 ? 392 LEU A CD2 1 
ATOM   1817  N  N   . GLU A 1 394 ? 121.561 79.110  137.343 1.00 163.81 ? 393 GLU A N   1 
ATOM   1818  C  CA  . GLU A 1 394 ? 122.984 79.192  137.027 1.00 217.44 ? 393 GLU A CA  1 
ATOM   1819  C  C   . GLU A 1 394 ? 123.396 78.003  136.156 1.00 230.51 ? 393 GLU A C   1 
ATOM   1820  O  O   . GLU A 1 394 ? 123.980 78.185  135.078 1.00 181.26 ? 393 GLU A O   1 
ATOM   1821  C  CB  . GLU A 1 394 ? 123.835 79.274  138.296 1.00 234.09 ? 393 GLU A CB  1 
ATOM   1822  C  CG  . GLU A 1 394 ? 125.311 79.466  137.990 1.00 316.20 ? 393 GLU A CG  1 
ATOM   1823  C  CD  . GLU A 1 394 ? 126.106 80.228  139.040 1.00 402.95 ? 393 GLU A CD  1 
ATOM   1824  O  OE1 . GLU A 1 394 ? 125.940 79.915  140.236 1.00 476.71 ? 393 GLU A OE1 1 
ATOM   1825  O  OE2 . GLU A 1 394 ? 126.890 81.132  138.659 1.00 451.11 ? 393 GLU A OE2 1 
ATOM   1826  N  N   . SER A 1 395 ? 123.086 76.803  136.666 1.00 243.35 ? 394 SER A N   1 
ATOM   1827  C  CA  . SER A 1 395 ? 123.427 75.531  136.040 1.00 250.19 ? 394 SER A CA  1 
ATOM   1828  C  C   . SER A 1 395 ? 122.509 75.202  134.857 1.00 240.61 ? 394 SER A C   1 
ATOM   1829  O  O   . SER A 1 395 ? 122.904 74.453  133.962 1.00 267.75 ? 394 SER A O   1 
ATOM   1830  C  CB  . SER A 1 395 ? 123.391 74.421  137.069 1.00 264.09 ? 394 SER A CB  1 
ATOM   1831  O  OG  . SER A 1 395 ? 124.306 74.656  138.134 1.00 271.38 ? 394 SER A OG  1 
ATOM   1832  N  N   . ASN A 1 396 ? 121.284 75.754  134.862 1.00 199.61 ? 395 ASN A N   1 
ATOM   1833  C  CA  . ASN A 1 396 ? 120.273 75.513  133.846 1.00 214.25 ? 395 ASN A CA  1 
ATOM   1834  C  C   . ASN A 1 396 ? 120.059 76.812  133.075 1.00 190.38 ? 395 ASN A C   1 
ATOM   1835  O  O   . ASN A 1 396 ? 119.760 77.842  133.646 1.00 149.23 ? 395 ASN A O   1 
ATOM   1836  C  CB  . ASN A 1 396 ? 119.008 74.964  134.510 1.00 228.13 ? 395 ASN A CB  1 
ATOM   1837  C  CG  . ASN A 1 396 ? 119.280 73.634  135.167 1.00 203.73 ? 395 ASN A CG  1 
ATOM   1838  O  OD1 . ASN A 1 396 ? 119.635 72.688  134.475 1.00 254.51 ? 395 ASN A OD1 1 
ATOM   1839  N  ND2 . ASN A 1 396 ? 119.156 73.544  136.483 1.00 225.42 ? 395 ASN A ND2 1 
ATOM   1840  N  N   . LYS A 1 397 ? 120.210 76.764  131.757 1.00 201.27 ? 396 LYS A N   1 
ATOM   1841  C  CA  . LYS A 1 397 ? 120.453 77.970  130.980 1.00 237.04 ? 396 LYS A CA  1 
ATOM   1842  C  C   . LYS A 1 397 ? 119.336 78.236  129.966 1.00 198.06 ? 396 LYS A C   1 
ATOM   1843  O  O   . LYS A 1 397 ? 119.207 79.391  129.542 1.00 183.11 ? 396 LYS A O   1 
ATOM   1844  C  CB  . LYS A 1 397 ? 121.843 77.820  130.350 1.00 351.73 ? 396 LYS A CB  1 
ATOM   1845  C  CG  . LYS A 1 397 ? 122.927 77.367  131.335 1.00 366.99 ? 396 LYS A CG  1 
ATOM   1846  C  CD  . LYS A 1 397 ? 124.314 77.300  130.758 1.00 413.20 ? 396 LYS A CD  1 
ATOM   1847  C  CE  . LYS A 1 397 ? 125.351 76.889  131.783 1.00 421.10 ? 396 LYS A CE  1 
ATOM   1848  N  NZ  . LYS A 1 397 ? 125.632 77.968  132.761 1.00 418.60 ? 396 LYS A NZ  1 
ATOM   1849  N  N   . ASP A 1 398 ? 118.559 77.190  129.589 1.00 214.83 ? 397 ASP A N   1 
ATOM   1850  C  CA  . ASP A 1 398 ? 117.331 77.346  128.818 1.00 312.11 ? 397 ASP A CA  1 
ATOM   1851  C  C   . ASP A 1 398 ? 116.162 76.725  129.597 1.00 210.49 ? 397 ASP A C   1 
ATOM   1852  O  O   . ASP A 1 398 ? 115.348 75.956  129.074 1.00 185.25 ? 397 ASP A O   1 
ATOM   1853  C  CB  . ASP A 1 398 ? 117.538 76.805  127.399 1.00 424.59 ? 397 ASP A CB  1 
ATOM   1854  C  CG  . ASP A 1 398 ? 116.472 77.215  126.390 1.00 508.74 ? 397 ASP A CG  1 
ATOM   1855  O  OD1 . ASP A 1 398 ? 115.627 78.069  126.734 1.00 523.51 ? 397 ASP A OD1 1 
ATOM   1856  O  OD2 . ASP A 1 398 ? 116.494 76.676  125.266 1.00 544.15 ? 397 ASP A OD2 1 
ATOM   1857  N  N   . LEU A 1 399 ? 116.098 77.114  130.872 1.00 125.26 ? 398 LEU A N   1 
ATOM   1858  C  CA  . LEU A 1 399 ? 114.966 76.899  131.735 1.00 121.69 ? 398 LEU A CA  1 
ATOM   1859  C  C   . LEU A 1 399 ? 114.166 78.189  131.906 1.00 118.46 ? 398 LEU A C   1 
ATOM   1860  O  O   . LEU A 1 399 ? 114.747 79.188  132.275 1.00 145.16 ? 398 LEU A O   1 
ATOM   1861  C  CB  . LEU A 1 399 ? 115.582 76.537  133.067 1.00 105.43 ? 398 LEU A CB  1 
ATOM   1862  C  CG  . LEU A 1 399 ? 114.645 76.058  134.162 1.00 112.64 ? 398 LEU A CG  1 
ATOM   1863  C  CD1 . LEU A 1 399 ? 114.436 74.557  134.020 1.00 151.34 ? 398 LEU A CD1 1 
ATOM   1864  C  CD2 . LEU A 1 399 ? 115.221 76.404  135.522 1.00 132.09 ? 398 LEU A CD2 1 
ATOM   1865  N  N   . LEU A 1 400 ? 112.853 78.198  131.658 1.00 104.22 ? 399 LEU A N   1 
ATOM   1866  C  CA  . LEU A 1 400 ? 112.034 79.262  132.223 1.00 99.58  ? 399 LEU A CA  1 
ATOM   1867  C  C   . LEU A 1 400 ? 111.786 78.947  133.678 1.00 96.68  ? 399 LEU A C   1 
ATOM   1868  O  O   . LEU A 1 400 ? 111.388 77.835  133.981 1.00 101.26 ? 399 LEU A O   1 
ATOM   1869  C  CB  . LEU A 1 400 ? 110.673 79.393  131.559 1.00 91.02  ? 399 LEU A CB  1 
ATOM   1870  C  CG  . LEU A 1 400 ? 110.737 79.611  130.051 1.00 113.12 ? 399 LEU A CG  1 
ATOM   1871  C  CD1 . LEU A 1 400 ? 109.388 80.127  129.543 1.00 88.79  ? 399 LEU A CD1 1 
ATOM   1872  C  CD2 . LEU A 1 400 ? 111.875 80.502  129.555 1.00 122.35 ? 399 LEU A CD2 1 
ATOM   1873  N  N   . LEU A 1 401 ? 112.006 79.919  134.554 1.00 88.17  ? 400 LEU A N   1 
ATOM   1874  C  CA  . LEU A 1 401 ? 111.764 79.703  135.966 1.00 79.64  ? 400 LEU A CA  1 
ATOM   1875  C  C   . LEU A 1 401 ? 110.867 80.835  136.423 1.00 91.88  ? 400 LEU A C   1 
ATOM   1876  O  O   . LEU A 1 401 ? 111.319 81.967  136.641 1.00 130.51 ? 400 LEU A O   1 
ATOM   1877  C  CB  . LEU A 1 401 ? 113.102 79.688  136.676 1.00 92.35  ? 400 LEU A CB  1 
ATOM   1878  C  CG  . LEU A 1 401 ? 113.065 79.784  138.176 1.00 119.79 ? 400 LEU A CG  1 
ATOM   1879  C  CD1 . LEU A 1 401 ? 112.276 78.632  138.716 1.00 127.70 ? 400 LEU A CD1 1 
ATOM   1880  C  CD2 . LEU A 1 401 ? 114.485 79.751  138.687 1.00 167.14 ? 400 LEU A CD2 1 
ATOM   1881  N  N   . THR A 1 402 ? 109.581 80.505  136.558 1.00 88.06  ? 401 THR A N   1 
ATOM   1882  C  CA  . THR A 1 402 ? 108.561 81.396  137.109 1.00 76.23  ? 401 THR A CA  1 
ATOM   1883  C  C   . THR A 1 402 ? 108.732 81.445  138.605 1.00 93.99  ? 401 THR A C   1 
ATOM   1884  O  O   . THR A 1 402 ? 109.204 80.475  139.189 1.00 102.52 ? 401 THR A O   1 
ATOM   1885  C  CB  . THR A 1 402 ? 107.150 80.953  136.723 1.00 89.45  ? 401 THR A CB  1 
ATOM   1886  O  OG1 . THR A 1 402 ? 106.892 79.616  137.168 1.00 85.72  ? 401 THR A OG1 1 
ATOM   1887  C  CG2 . THR A 1 402 ? 106.984 80.996  135.205 1.00 121.53 ? 401 THR A CG2 1 
ATOM   1888  N  N   . SER A 1 403 ? 108.370 82.576  139.216 1.00 95.20  ? 402 SER A N   1 
ATOM   1889  C  CA  . SER A 1 403 ? 108.646 82.778  140.642 1.00 96.87  ? 402 SER A CA  1 
ATOM   1890  C  C   . SER A 1 403 ? 107.733 83.837  141.216 1.00 94.69  ? 402 SER A C   1 
ATOM   1891  O  O   . SER A 1 403 ? 106.964 84.445  140.478 1.00 139.05 ? 402 SER A O   1 
ATOM   1892  C  CB  . SER A 1 403 ? 110.054 83.203  140.870 1.00 93.68  ? 402 SER A CB  1 
ATOM   1893  O  OG  . SER A 1 403 ? 110.267 84.471  140.264 1.00 107.75 ? 402 SER A OG  1 
ATOM   1894  N  N   . SER A 1 404 ? 107.866 84.086  142.512 1.00 75.93  ? 403 SER A N   1 
ATOM   1895  C  CA  . SER A 1 404 ? 107.180 85.207  143.104 1.00 90.60  ? 403 SER A CA  1 
ATOM   1896  C  C   . SER A 1 404 ? 108.033 86.469  142.954 1.00 73.82  ? 403 SER A C   1 
ATOM   1897  O  O   . SER A 1 404 ? 107.714 87.484  143.575 1.00 102.22 ? 403 SER A O   1 
ATOM   1898  C  CB  . SER A 1 404 ? 106.850 84.951  144.568 1.00 154.30 ? 403 SER A CB  1 
ATOM   1899  O  OG  . SER A 1 404 ? 106.127 83.740  144.774 1.00 205.09 ? 403 SER A OG  1 
ATOM   1900  N  N   . TYR A 1 405 ? 109.087 86.498  142.142 1.00 57.74  ? 404 TYR A N   1 
ATOM   1901  C  CA  . TYR A 1 405 ? 109.998 87.640  142.203 1.00 83.39  ? 404 TYR A CA  1 
ATOM   1902  C  C   . TYR A 1 405 ? 109.399 89.024  141.895 1.00 77.18  ? 404 TYR A C   1 
ATOM   1903  O  O   . TYR A 1 405 ? 109.651 89.947  142.683 1.00 72.18  ? 404 TYR A O   1 
ATOM   1904  C  CB  . TYR A 1 405 ? 111.148 87.402  141.249 1.00 101.85 ? 404 TYR A CB  1 
ATOM   1905  C  CG  . TYR A 1 405 ? 112.091 88.583  141.221 1.00 72.82  ? 404 TYR A CG  1 
ATOM   1906  C  CD1 . TYR A 1 405 ? 112.813 88.946  142.294 1.00 87.71  ? 404 TYR A CD1 1 
ATOM   1907  C  CD2 . TYR A 1 405 ? 112.212 89.315  140.092 1.00 87.77  ? 404 TYR A CD2 1 
ATOM   1908  C  CE1 . TYR A 1 405 ? 113.664 90.021  142.222 1.00 144.94 ? 404 TYR A CE1 1 
ATOM   1909  C  CE2 . TYR A 1 405 ? 113.049 90.384  140.001 1.00 86.58  ? 404 TYR A CE2 1 
ATOM   1910  C  CZ  . TYR A 1 405 ? 113.786 90.747  141.060 1.00 101.84 ? 404 TYR A CZ  1 
ATOM   1911  O  OH  . TYR A 1 405 ? 114.571 91.840  140.869 1.00 93.11  ? 404 TYR A OH  1 
ATOM   1912  N  N   . LEU A 1 406 ? 108.606 89.165  140.821 1.00 56.54  ? 405 LEU A N   1 
ATOM   1913  C  CA  . LEU A 1 406 ? 107.824 90.399  140.706 1.00 68.44  ? 405 LEU A CA  1 
ATOM   1914  C  C   . LEU A 1 406 ? 106.594 90.630  141.662 1.00 78.49  ? 405 LEU A C   1 
ATOM   1915  O  O   . LEU A 1 406 ? 105.963 91.703  141.616 1.00 74.68  ? 405 LEU A O   1 
ATOM   1916  C  CB  . LEU A 1 406 ? 107.340 90.436  139.266 1.00 59.99  ? 405 LEU A CB  1 
ATOM   1917  C  CG  . LEU A 1 406 ? 108.289 90.977  138.241 1.00 62.69  ? 405 LEU A CG  1 
ATOM   1918  C  CD1 . LEU A 1 406 ? 107.487 91.586  137.116 1.00 65.95  ? 405 LEU A CD1 1 
ATOM   1919  C  CD2 . LEU A 1 406 ? 109.125 92.083  138.789 1.00 78.78  ? 405 LEU A CD2 1 
ATOM   1920  N  N   . SER A 1 407 ? 106.227 89.684  142.526 1.00 74.22  ? 406 SER A N   1 
ATOM   1921  C  CA  . SER A 1 407 ? 105.018 89.754  143.333 1.00 88.79  ? 406 SER A CA  1 
ATOM   1922  C  C   . SER A 1 407 ? 105.058 90.873  144.388 1.00 142.88 ? 406 SER A C   1 
ATOM   1923  O  O   . SER A 1 407 ? 104.034 91.522  144.636 1.00 139.25 ? 406 SER A O   1 
ATOM   1924  C  CB  . SER A 1 407 ? 104.893 88.438  144.026 1.00 128.12 ? 406 SER A CB  1 
ATOM   1925  O  OG  . SER A 1 407 ? 103.786 88.344  144.879 1.00 193.07 ? 406 SER A OG  1 
ATOM   1926  N  N   . ASP A 1 408 ? 106.240 91.108  145.007 1.00 148.89 ? 407 ASP A N   1 
ATOM   1927  C  CA  . ASP A 1 408 ? 106.423 92.024  146.137 1.00 172.03 ? 407 ASP A CA  1 
ATOM   1928  C  C   . ASP A 1 408 ? 106.602 93.479  145.653 1.00 137.55 ? 407 ASP A C   1 
ATOM   1929  O  O   . ASP A 1 408 ? 107.548 94.194  146.025 1.00 115.63 ? 407 ASP A O   1 
ATOM   1930  C  CB  . ASP A 1 408 ? 107.618 91.577  147.001 1.00 293.70 ? 407 ASP A CB  1 
ATOM   1931  C  CG  . ASP A 1 408 ? 107.623 90.127  147.486 1.00 376.21 ? 407 ASP A CG  1 
ATOM   1932  O  OD1 . ASP A 1 408 ? 106.524 89.617  147.792 1.00 382.69 ? 407 ASP A OD1 1 
ATOM   1933  O  OD2 . ASP A 1 408 ? 108.729 89.524  147.572 1.00 453.98 ? 407 ASP A OD2 1 
ATOM   1934  N  N   . SER A 1 409 ? 105.658 93.927  144.809 1.00 201.54 ? 408 SER A N   1 
ATOM   1935  C  CA  . SER A 1 409 ? 105.759 95.123  143.972 1.00 173.02 ? 408 SER A CA  1 
ATOM   1936  C  C   . SER A 1 409 ? 105.686 96.452  144.735 1.00 173.35 ? 408 SER A C   1 
ATOM   1937  O  O   . SER A 1 409 ? 105.810 97.484  144.117 1.00 126.58 ? 408 SER A O   1 
ATOM   1938  C  CB  . SER A 1 409 ? 104.613 95.075  142.964 1.00 184.27 ? 408 SER A CB  1 
ATOM   1939  O  OG  . SER A 1 409 ? 103.339 95.226  143.617 1.00 202.75 ? 408 SER A OG  1 
ATOM   1940  N  N   . GLY A 1 410 ? 105.422 96.479  146.049 1.00 248.60 ? 409 GLY A N   1 
ATOM   1941  C  CA  . GLY A 1 410 ? 105.174 97.741  146.752 1.00 267.07 ? 409 GLY A CA  1 
ATOM   1942  C  C   . GLY A 1 410 ? 103.717 98.237  146.737 1.00 235.62 ? 409 GLY A C   1 
ATOM   1943  O  O   . GLY A 1 410 ? 103.408 99.227  147.412 1.00 179.13 ? 409 GLY A O   1 
ATOM   1944  N  N   . SER A 1 411 ? 102.832 97.556  145.980 1.00 211.30 ? 410 SER A N   1 
ATOM   1945  C  CA  . SER A 1 411 ? 101.385 97.740  145.997 1.00 223.95 ? 410 SER A CA  1 
ATOM   1946  C  C   . SER A 1 411 ? 100.897 99.185  145.742 1.00 181.79 ? 410 SER A C   1 
ATOM   1947  O  O   . SER A 1 411 ? 99.725  99.503  145.996 1.00 169.02 ? 410 SER A O   1 
ATOM   1948  C  CB  . SER A 1 411 ? 100.836 97.165  147.286 1.00 338.07 ? 410 SER A CB  1 
ATOM   1949  O  OG  . SER A 1 411 ? 101.136 95.776  147.376 1.00 353.76 ? 410 SER A OG  1 
ATOM   1950  N  N   . THR A 1 412 ? 101.764 100.065 145.213 1.00 161.67 ? 411 THR A N   1 
ATOM   1951  C  CA  . THR A 1 412 ? 101.391 101.046 144.189 1.00 166.19 ? 411 THR A CA  1 
ATOM   1952  C  C   . THR A 1 412 ? 102.521 101.085 143.158 1.00 149.94 ? 411 THR A C   1 
ATOM   1953  O  O   . THR A 1 412 ? 102.984 102.142 142.757 1.00 127.89 ? 411 THR A O   1 
ATOM   1954  C  CB  . THR A 1 412 ? 101.030 102.373 144.854 1.00 197.06 ? 411 THR A CB  1 
ATOM   1955  O  OG1 . THR A 1 412 ? 99.751  102.134 145.448 1.00 256.53 ? 411 THR A OG1 1 
ATOM   1956  C  CG2 . THR A 1 412 ? 100.957 103.566 143.931 1.00 165.06 ? 411 THR A CG2 1 
ATOM   1957  N  N   . GLY A 1 413 ? 102.975 99.885  142.756 1.00 134.25 ? 412 GLY A N   1 
ATOM   1958  C  CA  . GLY A 1 413 ? 103.880 99.689  141.650 1.00 88.95  ? 412 GLY A CA  1 
ATOM   1959  C  C   . GLY A 1 413 ? 105.315 100.129 141.956 1.00 114.11 ? 412 GLY A C   1 
ATOM   1960  O  O   . GLY A 1 413 ? 106.221 99.805  141.158 1.00 161.13 ? 412 GLY A O   1 
ATOM   1961  N  N   . GLU A 1 414 ? 105.551 100.834 143.088 1.00 82.62  ? 413 GLU A N   1 
ATOM   1962  C  CA  . GLU A 1 414 ? 106.656 101.796 143.143 1.00 115.88 ? 413 GLU A CA  1 
ATOM   1963  C  C   . GLU A 1 414 ? 108.037 101.157 142.922 1.00 118.65 ? 413 GLU A C   1 
ATOM   1964  O  O   . GLU A 1 414 ? 108.933 101.795 142.360 1.00 146.14 ? 413 GLU A O   1 
ATOM   1965  C  CB  . GLU A 1 414 ? 106.519 102.595 144.436 1.00 147.32 ? 413 GLU A CB  1 
ATOM   1966  C  CG  . GLU A 1 414 ? 106.738 101.821 145.723 1.00 205.91 ? 413 GLU A CG  1 
ATOM   1967  C  CD  . GLU A 1 414 ? 106.136 102.434 146.986 1.00 293.77 ? 413 GLU A CD  1 
ATOM   1968  O  OE1 . GLU A 1 414 ? 105.164 103.221 146.876 1.00 308.50 ? 413 GLU A OE1 1 
ATOM   1969  O  OE2 . GLU A 1 414 ? 106.642 102.129 148.101 1.00 352.31 ? 413 GLU A OE2 1 
ATOM   1970  N  N   . HIS A 1 415 ? 108.187 99.907  143.352 1.00 121.00 ? 414 HIS A N   1 
ATOM   1971  C  CA  . HIS A 1 415 ? 109.427 99.172  143.243 1.00 126.95 ? 414 HIS A CA  1 
ATOM   1972  C  C   . HIS A 1 415 ? 109.680 98.553  141.877 1.00 125.21 ? 414 HIS A C   1 
ATOM   1973  O  O   . HIS A 1 415 ? 110.820 98.209  141.590 1.00 144.09 ? 414 HIS A O   1 
ATOM   1974  C  CB  . HIS A 1 415 ? 109.403 98.011  144.232 1.00 158.35 ? 414 HIS A CB  1 
ATOM   1975  C  CG  . HIS A 1 415 ? 109.495 98.468  145.636 1.00 160.49 ? 414 HIS A CG  1 
ATOM   1976  N  ND1 . HIS A 1 415 ? 108.982 97.749  146.698 1.00 184.04 ? 414 HIS A ND1 1 
ATOM   1977  C  CD2 . HIS A 1 415 ? 110.061 99.590  146.104 1.00 122.61 ? 414 HIS A CD2 1 
ATOM   1978  C  CE1 . HIS A 1 415 ? 109.240 98.446  147.794 1.00 249.68 ? 414 HIS A CE1 1 
ATOM   1979  N  NE2 . HIS A 1 415 ? 109.890 99.558  147.453 1.00 220.83 ? 414 HIS A NE2 1 
ATOM   1980  N  N   . THR A 1 416 ? 108.673 98.411  141.032 1.00 90.84  ? 415 THR A N   1 
ATOM   1981  C  CA  . THR A 1 416 ? 108.830 97.607  139.842 1.00 65.67  ? 415 THR A CA  1 
ATOM   1982  C  C   . THR A 1 416 ? 109.933 98.064  138.876 1.00 66.27  ? 415 THR A C   1 
ATOM   1983  O  O   . THR A 1 416 ? 110.571 97.196  138.277 1.00 82.19  ? 415 THR A O   1 
ATOM   1984  C  CB  . THR A 1 416 ? 107.502 97.556  139.100 1.00 68.27  ? 415 THR A CB  1 
ATOM   1985  O  OG1 . THR A 1 416 ? 106.789 96.725  139.998 1.00 93.81  ? 415 THR A OG1 1 
ATOM   1986  C  CG2 . THR A 1 416 ? 107.525 96.829  137.778 1.00 113.88 ? 415 THR A CG2 1 
ATOM   1987  N  N   . LYS A 1 417 ? 110.153 99.372  138.634 1.00 85.02  ? 416 LYS A N   1 
ATOM   1988  C  CA  . LYS A 1 417 ? 111.184 99.773  137.681 1.00 79.82  ? 416 LYS A CA  1 
ATOM   1989  C  C   . LYS A 1 417 ? 112.467 99.101  138.110 1.00 102.13 ? 416 LYS A C   1 
ATOM   1990  O  O   . LYS A 1 417 ? 113.314 98.870  137.237 1.00 119.15 ? 416 LYS A O   1 
ATOM   1991  C  CB  . LYS A 1 417 ? 111.390 101.294 137.682 1.00 128.38 ? 416 LYS A CB  1 
ATOM   1992  C  CG  . LYS A 1 417 ? 112.534 101.869 136.834 1.00 111.61 ? 416 LYS A CG  1 
ATOM   1993  C  CD  . LYS A 1 417 ? 112.665 103.374 136.945 1.00 169.80 ? 416 LYS A CD  1 
ATOM   1994  C  CE  . LYS A 1 417 ? 114.007 103.899 136.473 1.00 217.16 ? 416 LYS A CE  1 
ATOM   1995  N  NZ  . LYS A 1 417 ? 114.091 105.379 136.614 1.00 292.85 ? 416 LYS A NZ  1 
ATOM   1996  N  N   . SER A 1 418 ? 112.609 98.863  139.448 1.00 82.56  ? 417 SER A N   1 
ATOM   1997  C  CA  . SER A 1 418 ? 113.878 98.470  140.032 1.00 103.81 ? 417 SER A CA  1 
ATOM   1998  C  C   . SER A 1 418 ? 113.909 96.954  140.094 1.00 81.79  ? 417 SER A C   1 
ATOM   1999  O  O   . SER A 1 418 ? 114.955 96.394  139.758 1.00 151.31 ? 417 SER A O   1 
ATOM   2000  C  CB  . SER A 1 418 ? 114.118 99.209  141.318 1.00 112.73 ? 417 SER A CB  1 
ATOM   2001  O  OG  . SER A 1 418 ? 113.432 98.597  142.384 1.00 159.20 ? 417 SER A OG  1 
ATOM   2002  N  N   . LEU A 1 419 ? 112.816 96.286  140.487 1.00 67.14  ? 418 LEU A N   1 
ATOM   2003  C  CA  . LEU A 1 419 ? 112.826 94.824  140.472 1.00 71.74  ? 418 LEU A CA  1 
ATOM   2004  C  C   . LEU A 1 419 ? 113.111 94.315  139.064 1.00 71.33  ? 418 LEU A C   1 
ATOM   2005  O  O   . LEU A 1 419 ? 113.889 93.343  138.959 1.00 61.59  ? 418 LEU A O   1 
ATOM   2006  C  CB  . LEU A 1 419 ? 111.512 94.203  140.908 1.00 62.49  ? 418 LEU A CB  1 
ATOM   2007  C  CG  . LEU A 1 419 ? 111.175 94.379  142.348 1.00 101.53 ? 418 LEU A CG  1 
ATOM   2008  C  CD1 . LEU A 1 419 ? 109.716 93.993  142.609 1.00 168.10 ? 418 LEU A CD1 1 
ATOM   2009  C  CD2 . LEU A 1 419 ? 112.174 93.588  143.178 1.00 164.74 ? 418 LEU A CD2 1 
ATOM   2010  N  N   . VAL A 1 420 ? 112.508 94.929  138.029 1.00 51.28  ? 419 VAL A N   1 
ATOM   2011  C  CA  . VAL A 1 420 ? 112.682 94.450  136.675 1.00 47.37  ? 419 VAL A CA  1 
ATOM   2012  C  C   . VAL A 1 420 ? 114.070 94.748  136.189 1.00 60.23  ? 419 VAL A C   1 
ATOM   2013  O  O   . VAL A 1 420 ? 114.686 93.818  135.672 1.00 68.89  ? 419 VAL A O   1 
ATOM   2014  C  CB  . VAL A 1 420 ? 111.675 95.029  135.718 1.00 53.32  ? 419 VAL A CB  1 
ATOM   2015  C  CG1 . VAL A 1 420 ? 112.099 94.807  134.288 1.00 52.74  ? 419 VAL A CG1 1 
ATOM   2016  C  CG2 . VAL A 1 420 ? 110.288 94.447  136.014 1.00 53.46  ? 419 VAL A CG2 1 
ATOM   2017  N  N   . THR A 1 421 ? 114.580 95.971  136.353 1.00 61.73  ? 420 THR A N   1 
ATOM   2018  C  CA  . THR A 1 421 ? 115.887 96.231  135.763 1.00 79.94  ? 420 THR A CA  1 
ATOM   2019  C  C   . THR A 1 421 ? 117.045 95.648  136.564 1.00 76.16  ? 420 THR A C   1 
ATOM   2020  O  O   . THR A 1 421 ? 118.102 95.511  135.972 1.00 162.01 ? 420 THR A O   1 
ATOM   2021  C  CB  . THR A 1 421 ? 116.154 97.713  135.538 1.00 88.23  ? 420 THR A CB  1 
ATOM   2022  O  OG1 . THR A 1 421 ? 116.023 98.485  136.720 1.00 113.54 ? 420 THR A OG1 1 
ATOM   2023  C  CG2 . THR A 1 421 ? 115.161 98.293  134.586 1.00 137.77 ? 420 THR A CG2 1 
ATOM   2024  N  N   . GLN A 1 422 ? 116.920 95.344  137.849 1.00 74.16  ? 421 GLN A N   1 
ATOM   2025  C  CA  . GLN A 1 422 ? 117.933 94.533  138.493 1.00 105.81 ? 421 GLN A CA  1 
ATOM   2026  C  C   . GLN A 1 422 ? 117.952 93.125  137.895 1.00 77.44  ? 421 GLN A C   1 
ATOM   2027  O  O   . GLN A 1 422 ? 119.017 92.585  137.621 1.00 95.29  ? 421 GLN A O   1 
ATOM   2028  C  CB  . GLN A 1 422 ? 117.717 94.409  139.997 1.00 144.46 ? 421 GLN A CB  1 
ATOM   2029  C  CG  . GLN A 1 422 ? 118.086 95.648  140.780 1.00 183.79 ? 421 GLN A CG  1 
ATOM   2030  C  CD  . GLN A 1 422 ? 117.674 95.523  142.234 1.00 280.65 ? 421 GLN A CD  1 
ATOM   2031  O  OE1 . GLN A 1 422 ? 117.123 94.516  142.686 1.00 201.99 ? 421 GLN A OE1 1 
ATOM   2032  N  NE2 . GLN A 1 422 ? 117.936 96.572  142.998 1.00 382.67 ? 421 GLN A NE2 1 
ATOM   2033  N  N   . TYR A 1 423 ? 116.816 92.494  137.715 1.00 63.05  ? 422 TYR A N   1 
ATOM   2034  C  CA  . TYR A 1 423 ? 116.836 91.105  137.305 1.00 72.78  ? 422 TYR A CA  1 
ATOM   2035  C  C   . TYR A 1 423 ? 117.382 90.925  135.899 1.00 70.35  ? 422 TYR A C   1 
ATOM   2036  O  O   . TYR A 1 423 ? 118.185 90.044  135.694 1.00 86.99  ? 422 TYR A O   1 
ATOM   2037  C  CB  . TYR A 1 423 ? 115.414 90.607  137.358 1.00 68.78  ? 422 TYR A CB  1 
ATOM   2038  C  CG  . TYR A 1 423 ? 115.248 89.145  137.072 1.00 58.04  ? 422 TYR A CG  1 
ATOM   2039  C  CD1 . TYR A 1 423 ? 115.285 88.660  135.806 1.00 74.03  ? 422 TYR A CD1 1 
ATOM   2040  C  CD2 . TYR A 1 423 ? 115.028 88.291  138.100 1.00 98.13  ? 422 TYR A CD2 1 
ATOM   2041  C  CE1 . TYR A 1 423 ? 115.118 87.318  135.537 1.00 127.29 ? 422 TYR A CE1 1 
ATOM   2042  C  CE2 . TYR A 1 423 ? 114.863 86.941  137.860 1.00 163.90 ? 422 TYR A CE2 1 
ATOM   2043  C  CZ  . TYR A 1 423 ? 114.905 86.448  136.575 1.00 120.21 ? 422 TYR A CZ  1 
ATOM   2044  O  OH  . TYR A 1 423 ? 114.737 85.110  136.393 1.00 164.29 ? 422 TYR A OH  1 
ATOM   2045  N  N   . LEU A 1 424 ? 116.959 91.752  134.945 1.00 74.29  ? 423 LEU A N   1 
ATOM   2046  C  CA  . LEU A 1 424 ? 117.540 91.726  133.624 1.00 81.21  ? 423 LEU A CA  1 
ATOM   2047  C  C   . LEU A 1 424 ? 119.060 91.876  133.697 1.00 108.89 ? 423 LEU A C   1 
ATOM   2048  O  O   . LEU A 1 424 ? 119.774 91.084  133.097 1.00 150.58 ? 423 LEU A O   1 
ATOM   2049  C  CB  . LEU A 1 424 ? 116.954 92.873  132.811 1.00 94.84  ? 423 LEU A CB  1 
ATOM   2050  C  CG  . LEU A 1 424 ? 115.576 92.578  132.244 1.00 82.74  ? 423 LEU A CG  1 
ATOM   2051  C  CD1 . LEU A 1 424 ? 114.974 93.771  131.453 1.00 69.87  ? 423 LEU A CD1 1 
ATOM   2052  C  CD2 . LEU A 1 424 ? 115.677 91.370  131.319 1.00 103.77 ? 423 LEU A CD2 1 
ATOM   2053  N  N   . ASN A 1 425 ? 119.546 92.874  134.421 1.00 107.80 ? 424 ASN A N   1 
ATOM   2054  C  CA  . ASN A 1 425 ? 120.971 93.127  134.564 1.00 141.89 ? 424 ASN A CA  1 
ATOM   2055  C  C   . ASN A 1 425 ? 121.699 91.930  135.169 1.00 110.81 ? 424 ASN A C   1 
ATOM   2056  O  O   . ASN A 1 425 ? 122.707 91.478  134.616 1.00 117.74 ? 424 ASN A O   1 
ATOM   2057  C  CB  . ASN A 1 425 ? 121.193 94.366  135.414 1.00 193.70 ? 424 ASN A CB  1 
ATOM   2058  C  CG  . ASN A 1 425 ? 122.605 94.918  135.380 1.00 205.37 ? 424 ASN A CG  1 
ATOM   2059  O  OD1 . ASN A 1 425 ? 123.263 94.988  134.336 1.00 185.75 ? 424 ASN A OD1 1 
ATOM   2060  N  ND2 . ASN A 1 425 ? 123.065 95.327  136.547 1.00 223.92 ? 424 ASN A ND2 1 
ATOM   2061  N  N   . ALA A 1 426 ? 121.186 91.402  136.277 1.00 94.08  ? 425 ALA A N   1 
ATOM   2062  C  CA  . ALA A 1 426 ? 121.817 90.273  136.953 1.00 126.67 ? 425 ALA A CA  1 
ATOM   2063  C  C   . ALA A 1 426 ? 121.918 89.004  136.084 1.00 115.34 ? 425 ALA A C   1 
ATOM   2064  O  O   . ALA A 1 426 ? 122.964 88.354  136.072 1.00 139.90 ? 425 ALA A O   1 
ATOM   2065  C  CB  . ALA A 1 426 ? 121.079 89.997  138.240 1.00 139.26 ? 425 ALA A CB  1 
ATOM   2066  N  N   . THR A 1 427 ? 120.853 88.640  135.362 1.00 115.12 ? 426 THR A N   1 
ATOM   2067  C  CA  . THR A 1 427 ? 120.879 87.499  134.456 1.00 135.40 ? 426 THR A CA  1 
ATOM   2068  C  C   . THR A 1 427 ? 121.646 87.766  133.156 1.00 121.52 ? 426 THR A C   1 
ATOM   2069  O  O   . THR A 1 427 ? 121.914 86.823  132.408 1.00 163.21 ? 426 THR A O   1 
ATOM   2070  C  CB  . THR A 1 427 ? 119.473 86.990  134.076 1.00 140.04 ? 426 THR A CB  1 
ATOM   2071  O  OG1 . THR A 1 427 ? 118.728 88.031  133.468 1.00 119.13 ? 426 THR A OG1 1 
ATOM   2072  C  CG2 . THR A 1 427 ? 118.705 86.446  135.257 1.00 131.57 ? 426 THR A CG2 1 
ATOM   2073  N  N   . GLY A 1 428 ? 121.998 89.012  132.873 1.00 121.65 ? 427 GLY A N   1 
ATOM   2074  C  CA  . GLY A 1 428 ? 122.733 89.324  131.660 1.00 184.77 ? 427 GLY A CA  1 
ATOM   2075  C  C   . GLY A 1 428 ? 121.860 89.319  130.401 1.00 156.41 ? 427 GLY A C   1 
ATOM   2076  O  O   . GLY A 1 428 ? 122.370 89.020  129.327 1.00 132.07 ? 427 GLY A O   1 
ATOM   2077  N  N   . ASN A 1 429 ? 120.568 89.665  130.549 1.00 136.48 ? 428 ASN A N   1 
ATOM   2078  C  CA  . ASN A 1 429 ? 119.600 89.759  129.471 1.00 118.38 ? 428 ASN A CA  1 
ATOM   2079  C  C   . ASN A 1 429 ? 119.498 88.444  128.703 1.00 131.79 ? 428 ASN A C   1 
ATOM   2080  O  O   . ASN A 1 429 ? 119.346 88.444  127.466 1.00 226.07 ? 428 ASN A O   1 
ATOM   2081  C  CB  . ASN A 1 429 ? 119.923 90.966  128.581 1.00 169.89 ? 428 ASN A CB  1 
ATOM   2082  C  CG  . ASN A 1 429 ? 119.576 92.315  129.191 1.00 213.82 ? 428 ASN A CG  1 
ATOM   2083  O  OD1 . ASN A 1 429 ? 119.808 92.550  130.383 1.00 128.96 ? 428 ASN A OD1 1 
ATOM   2084  N  ND2 . ASN A 1 429 ? 119.017 93.208  128.376 1.00 246.55 ? 428 ASN A ND2 1 
ATOM   2085  N  N   . ARG A 1 430 ? 119.548 87.312  129.420 1.00 106.33 ? 429 ARG A N   1 
ATOM   2086  C  CA  . ARG A 1 430 ? 119.144 86.048  128.815 1.00 124.89 ? 429 ARG A CA  1 
ATOM   2087  C  C   . ARG A 1 430 ? 117.618 86.067  128.585 1.00 137.59 ? 429 ARG A C   1 
ATOM   2088  O  O   . ARG A 1 430 ? 116.894 87.076  128.755 1.00 120.27 ? 429 ARG A O   1 
ATOM   2089  C  CB  . ARG A 1 430 ? 119.610 84.901  129.719 1.00 161.58 ? 429 ARG A CB  1 
ATOM   2090  C  CG  . ARG A 1 430 ? 121.086 84.560  129.613 1.00 218.12 ? 429 ARG A CG  1 
ATOM   2091  C  CD  . ARG A 1 430 ? 121.454 83.405  130.536 1.00 256.74 ? 429 ARG A CD  1 
ATOM   2092  N  NE  . ARG A 1 430 ? 121.612 83.837  131.923 1.00 273.64 ? 429 ARG A NE  1 
ATOM   2093  C  CZ  . ARG A 1 430 ? 121.603 83.060  133.013 1.00 285.91 ? 429 ARG A CZ  1 
ATOM   2094  N  NH1 . ARG A 1 430 ? 122.005 83.566  134.166 1.00 261.79 ? 429 ARG A NH1 1 
ATOM   2095  N  NH2 . ARG A 1 430 ? 121.219 81.788  132.989 1.00 321.20 ? 429 ARG A NH2 1 
ATOM   2096  N  N   . TRP A 1 431 ? 117.076 84.915  128.205 1.00 137.47 ? 430 TRP A N   1 
ATOM   2097  C  CA  . TRP A 1 431 ? 115.627 84.764  128.230 1.00 120.83 ? 430 TRP A CA  1 
ATOM   2098  C  C   . TRP A 1 431 ? 115.060 84.612  129.661 1.00 137.59 ? 430 TRP A C   1 
ATOM   2099  O  O   . TRP A 1 431 ? 115.709 84.124  130.589 1.00 138.27 ? 430 TRP A O   1 
ATOM   2100  C  CB  . TRP A 1 431 ? 115.226 83.603  127.299 1.00 99.83  ? 430 TRP A CB  1 
ATOM   2101  C  CG  . TRP A 1 431 ? 113.931 83.975  126.672 1.00 91.83  ? 430 TRP A CG  1 
ATOM   2102  C  CD1 . TRP A 1 431 ? 112.746 83.401  126.937 1.00 103.02 ? 430 TRP A CD1 1 
ATOM   2103  C  CD2 . TRP A 1 431 ? 113.661 85.021  125.712 1.00 112.84 ? 430 TRP A CD2 1 
ATOM   2104  N  NE1 . TRP A 1 431 ? 111.754 83.993  126.212 1.00 78.24  ? 430 TRP A NE1 1 
ATOM   2105  C  CE2 . TRP A 1 431 ? 112.281 84.988  125.462 1.00 70.19  ? 430 TRP A CE2 1 
ATOM   2106  C  CE3 . TRP A 1 431 ? 114.441 85.969  125.037 1.00 183.88 ? 430 TRP A CE3 1 
ATOM   2107  C  CZ2 . TRP A 1 431 ? 111.674 85.859  124.592 1.00 68.17  ? 430 TRP A CZ2 1 
ATOM   2108  C  CZ3 . TRP A 1 431 ? 113.841 86.829  124.151 1.00 152.43 ? 430 TRP A CZ3 1 
ATOM   2109  C  CH2 . TRP A 1 431 ? 112.472 86.765  123.932 1.00 124.62 ? 430 TRP A CH2 1 
ATOM   2110  N  N   . CYS A 1 432 ? 113.817 85.057  129.837 1.00 110.16 ? 431 CYS A N   1 
ATOM   2111  C  CA  . CYS A 1 432 ? 113.163 85.162  131.134 1.00 106.40 ? 431 CYS A CA  1 
ATOM   2112  C  C   . CYS A 1 432 ? 111.707 84.727  130.975 1.00 88.42  ? 431 CYS A C   1 
ATOM   2113  O  O   . CYS A 1 432 ? 111.176 84.692  129.876 1.00 75.58  ? 431 CYS A O   1 
ATOM   2114  C  CB  . CYS A 1 432 ? 113.184 86.614  131.616 1.00 84.09  ? 431 CYS A CB  1 
ATOM   2115  S  SG  . CYS A 1 432 ? 114.856 87.271  131.595 1.00 273.49 ? 431 CYS A SG  1 
ATOM   2116  N  N   . SER A 1 433 ? 111.025 84.442  132.059 1.00 76.58  ? 432 SER A N   1 
ATOM   2117  C  CA  . SER A 1 433 ? 109.582 84.366  132.025 1.00 81.93  ? 432 SER A CA  1 
ATOM   2118  C  C   . SER A 1 433 ? 108.921 85.290  133.052 1.00 56.20  ? 432 SER A C   1 
ATOM   2119  O  O   . SER A 1 433 ? 108.946 85.017  134.236 1.00 99.45  ? 432 SER A O   1 
ATOM   2120  C  CB  . SER A 1 433 ? 109.197 82.925  132.284 1.00 152.52 ? 432 SER A CB  1 
ATOM   2121  O  OG  . SER A 1 433 ? 109.734 82.398  133.494 1.00 117.06 ? 432 SER A OG  1 
ATOM   2122  N  N   . TRP A 1 434 ? 108.331 86.353  132.616 1.00 57.30  ? 433 TRP A N   1 
ATOM   2123  C  CA  . TRP A 1 434 ? 107.683 87.246  133.542 1.00 68.25  ? 433 TRP A CA  1 
ATOM   2124  C  C   . TRP A 1 434 ? 106.383 86.662  134.006 1.00 66.03  ? 433 TRP A C   1 
ATOM   2125  O  O   . TRP A 1 434 ? 105.591 86.208  133.186 1.00 106.67 ? 433 TRP A O   1 
ATOM   2126  C  CB  . TRP A 1 434 ? 107.473 88.598  132.849 1.00 74.43  ? 433 TRP A CB  1 
ATOM   2127  C  CG  . TRP A 1 434 ? 108.832 89.142  132.446 1.00 85.59  ? 433 TRP A CG  1 
ATOM   2128  C  CD1 . TRP A 1 434 ? 109.349 89.127  131.199 1.00 80.03  ? 433 TRP A CD1 1 
ATOM   2129  C  CD2 . TRP A 1 434 ? 109.855 89.724  133.279 1.00 72.16  ? 433 TRP A CD2 1 
ATOM   2130  N  NE1 . TRP A 1 434 ? 110.582 89.676  131.210 1.00 72.51  ? 433 TRP A NE1 1 
ATOM   2131  C  CE2 . TRP A 1 434 ? 110.918 90.032  132.470 1.00 63.24  ? 433 TRP A CE2 1 
ATOM   2132  C  CE3 . TRP A 1 434 ? 109.969 90.034  134.630 1.00 112.81 ? 433 TRP A CE3 1 
ATOM   2133  C  CZ2 . TRP A 1 434 ? 112.069 90.626  132.951 1.00 114.55 ? 433 TRP A CZ2 1 
ATOM   2134  C  CZ3 . TRP A 1 434 ? 111.114 90.617  135.094 1.00 96.16  ? 433 TRP A CZ3 1 
ATOM   2135  C  CH2 . TRP A 1 434 ? 112.159 90.900  134.278 1.00 95.08  ? 433 TRP A CH2 1 
ATOM   2136  N  N   . SER A 1 435 ? 106.164 86.722  135.307 1.00 63.91  ? 434 SER A N   1 
ATOM   2137  C  CA  . SER A 1 435 ? 104.937 86.237  135.885 1.00 75.69  ? 434 SER A CA  1 
ATOM   2138  C  C   . SER A 1 435 ? 104.795 86.770  137.267 1.00 76.04  ? 434 SER A C   1 
ATOM   2139  O  O   . SER A 1 435 ? 105.830 86.746  137.949 1.00 155.68 ? 434 SER A O   1 
ATOM   2140  C  CB  . SER A 1 435 ? 105.089 84.759  136.013 1.00 107.36 ? 434 SER A CB  1 
ATOM   2141  O  OG  . SER A 1 435 ? 106.288 84.348  136.738 1.00 80.92  ? 434 SER A OG  1 
ATOM   2142  N  N   . LEU A 1 436 ? 103.627 87.173  137.732 1.00 62.12  ? 435 LEU A N   1 
ATOM   2143  C  CA  . LEU A 1 436 ? 103.623 87.451  139.179 1.00 73.46  ? 435 LEU A CA  1 
ATOM   2144  C  C   . LEU A 1 436 ? 103.585 86.195  140.075 1.00 86.48  ? 435 LEU A C   1 
ATOM   2145  O  O   . LEU A 1 436 ? 103.856 86.362  141.273 1.00 151.62 ? 435 LEU A O   1 
ATOM   2146  C  CB  . LEU A 1 436 ? 102.525 88.447  139.577 1.00 75.91  ? 435 LEU A CB  1 
ATOM   2147  C  CG  . LEU A 1 436 ? 102.490 89.733  138.748 1.00 86.63  ? 435 LEU A CG  1 
ATOM   2148  C  CD1 . LEU A 1 436 ? 101.478 90.707  139.305 1.00 148.82 ? 435 LEU A CD1 1 
ATOM   2149  C  CD2 . LEU A 1 436 ? 103.807 90.423  138.680 1.00 82.41  ? 435 LEU A CD2 1 
ATOM   2150  N  N   . SER A 1 437 ? 103.291 84.979  139.594 1.00 70.50  ? 436 SER A N   1 
ATOM   2151  C  CA  . SER A 1 437 ? 103.520 83.824  140.447 1.00 94.06  ? 436 SER A CA  1 
ATOM   2152  C  C   . SER A 1 437 ? 103.724 82.548  139.640 1.00 112.11 ? 436 SER A C   1 
ATOM   2153  O  O   . SER A 1 437 ? 103.385 82.508  138.464 1.00 240.18 ? 436 SER A O   1 
ATOM   2154  C  CB  . SER A 1 437 ? 102.348 83.675  141.430 1.00 134.61 ? 436 SER A CB  1 
ATOM   2155  O  OG  . SER A 1 437 ? 102.432 82.512  142.269 1.00 138.52 ? 436 SER A OG  1 
ATOM   2156  N  N   . GLN A 1 438 ? 104.228 81.494  140.296 1.00 107.72 ? 437 GLN A N   1 
ATOM   2157  C  CA  . GLN A 1 438 ? 104.117 80.130  139.768 1.00 102.82 ? 437 GLN A CA  1 
ATOM   2158  C  C   . GLN A 1 438 ? 102.688 79.558  139.596 1.00 104.65 ? 437 GLN A C   1 
ATOM   2159  O  O   . GLN A 1 438 ? 102.518 78.620  138.809 1.00 135.58 ? 437 GLN A O   1 
ATOM   2160  C  CB  . GLN A 1 438 ? 104.920 79.178  140.636 1.00 97.49  ? 437 GLN A CB  1 
ATOM   2161  C  CG  . GLN A 1 438 ? 104.522 79.203  142.088 1.00 124.96 ? 437 GLN A CG  1 
ATOM   2162  C  CD  . GLN A 1 438 ? 105.189 78.047  142.785 1.00 169.90 ? 437 GLN A CD  1 
ATOM   2163  O  OE1 . GLN A 1 438 ? 106.173 77.495  142.294 1.00 87.32  ? 437 GLN A OE1 1 
ATOM   2164  N  NE2 . GLN A 1 438 ? 104.639 77.676  143.933 1.00 221.31 ? 437 GLN A NE2 1 
ATOM   2165  N  N   . ALA A 1 439 ? 101.660 80.083  140.274 1.00 93.42  ? 438 ALA A N   1 
ATOM   2166  C  CA  . ALA A 1 439 ? 100.315 79.539  140.102 1.00 120.29 ? 438 ALA A CA  1 
ATOM   2167  C  C   . ALA A 1 439 ? 99.184  80.560  140.254 1.00 129.82 ? 438 ALA A C   1 
ATOM   2168  O  O   . ALA A 1 439 ? 98.291  80.583  139.402 1.00 210.64 ? 438 ALA A O   1 
ATOM   2169  C  CB  . ALA A 1 439 ? 100.117 78.437  141.115 1.00 203.97 ? 438 ALA A CB  1 
ATOM   2170  N  N   . ARG A 1 440 ? 99.182  81.371  141.328 1.00 109.19 ? 439 ARG A N   1 
ATOM   2171  C  CA  . ARG A 1 440 ? 98.027  82.209  141.644 1.00 120.47 ? 439 ARG A CA  1 
ATOM   2172  C  C   . ARG A 1 440 ? 97.800  83.325  140.603 1.00 109.11 ? 439 ARG A C   1 
ATOM   2173  O  O   . ARG A 1 440 ? 98.718  83.714  139.864 1.00 111.46 ? 439 ARG A O   1 
ATOM   2174  C  CB  . ARG A 1 440 ? 98.263  82.785  143.048 1.00 166.20 ? 439 ARG A CB  1 
ATOM   2175  C  CG  . ARG A 1 440 ? 98.077  81.730  144.132 1.00 169.13 ? 439 ARG A CG  1 
ATOM   2176  C  CD  . ARG A 1 440 ? 98.690  82.140  145.461 1.00 196.25 ? 439 ARG A CD  1 
ATOM   2177  N  NE  . ARG A 1 440 ? 98.272  83.447  145.969 1.00 200.59 ? 439 ARG A NE  1 
ATOM   2178  C  CZ  . ARG A 1 440 ? 98.874  84.124  146.954 1.00 287.34 ? 439 ARG A CZ  1 
ATOM   2179  N  NH1 . ARG A 1 440 ? 98.415  85.311  147.330 1.00 322.82 ? 439 ARG A NH1 1 
ATOM   2180  N  NH2 . ARG A 1 440 ? 99.938  83.621  147.563 1.00 322.81 ? 439 ARG A NH2 1 
ATOM   2181  N  N   . LEU A 1 441 ? 96.571  83.878  140.553 1.00 118.97 ? 440 LEU A N   1 
ATOM   2182  C  CA  . LEU A 1 441 ? 96.193  84.957  139.623 1.00 126.42 ? 440 LEU A CA  1 
ATOM   2183  C  C   . LEU A 1 441 ? 96.991  86.252  139.805 1.00 104.33 ? 440 LEU A C   1 
ATOM   2184  O  O   . LEU A 1 441 ? 97.451  86.491  140.910 1.00 136.10 ? 440 LEU A O   1 
ATOM   2185  C  CB  . LEU A 1 441 ? 94.728  85.284  139.890 1.00 122.40 ? 440 LEU A CB  1 
ATOM   2186  C  CG  . LEU A 1 441 ? 93.726  84.203  139.570 1.00 143.17 ? 440 LEU A CG  1 
ATOM   2187  C  CD1 . LEU A 1 441 ? 92.379  84.589  140.173 1.00 217.65 ? 440 LEU A CD1 1 
ATOM   2188  C  CD2 . LEU A 1 441 ? 93.629  84.046  138.053 1.00 155.17 ? 440 LEU A CD2 1 
ATOM   2189  N  N   . LEU A 1 442 ? 97.138  87.118  138.782 1.00 97.52  ? 441 LEU A N   1 
ATOM   2190  C  CA  . LEU A 1 442 ? 97.659  88.484  139.005 1.00 79.86  ? 441 LEU A CA  1 
ATOM   2191  C  C   . LEU A 1 442 ? 96.863  89.173  140.110 1.00 101.65 ? 441 LEU A C   1 
ATOM   2192  O  O   . LEU A 1 442 ? 97.487  89.794  140.965 1.00 131.30 ? 441 LEU A O   1 
ATOM   2193  C  CB  . LEU A 1 442 ? 97.537  89.466  137.847 1.00 62.86  ? 441 LEU A CB  1 
ATOM   2194  C  CG  . LEU A 1 442 ? 98.230  89.077  136.564 1.00 103.98 ? 441 LEU A CG  1 
ATOM   2195  C  CD1 . LEU A 1 442 ? 97.972  90.085  135.407 1.00 108.42 ? 441 LEU A CD1 1 
ATOM   2196  C  CD2 . LEU A 1 442 ? 99.693  88.948  136.849 1.00 117.25 ? 441 LEU A CD2 1 
ATOM   2197  N  N   . THR A 1 443 ? 95.527  89.054  140.099 1.00 89.36  ? 442 THR A N   1 
ATOM   2198  C  CA  . THR A 1 443 ? 94.703  89.731  141.085 1.00 92.92  ? 442 THR A CA  1 
ATOM   2199  C  C   . THR A 1 443 ? 94.886  89.187  142.509 1.00 94.35  ? 442 THR A C   1 
ATOM   2200  O  O   . THR A 1 443 ? 94.320  89.726  143.457 1.00 132.70 ? 442 THR A O   1 
ATOM   2201  C  CB  . THR A 1 443 ? 93.229  89.759  140.647 1.00 144.03 ? 442 THR A CB  1 
ATOM   2202  O  OG1 . THR A 1 443 ? 93.082  89.750  139.221 1.00 161.66 ? 442 THR A OG1 1 
ATOM   2203  C  CG2 . THR A 1 443 ? 92.548  91.006  141.181 1.00 235.40 ? 442 THR A CG2 1 
ATOM   2204  N  N   . SER A 1 444 ? 95.690  88.151  142.715 1.00 112.50 ? 443 SER A N   1 
ATOM   2205  C  CA  . SER A 1 444 ? 96.084  87.739  144.057 1.00 155.12 ? 443 SER A CA  1 
ATOM   2206  C  C   . SER A 1 444 ? 97.087  88.706  144.694 1.00 109.35 ? 443 SER A C   1 
ATOM   2207  O  O   . SER A 1 444 ? 97.323  88.624  145.903 1.00 125.47 ? 443 SER A O   1 
ATOM   2208  C  CB  . SER A 1 444 ? 96.622  86.317  144.042 1.00 163.91 ? 443 SER A CB  1 
ATOM   2209  O  OG  . SER A 1 444 ? 96.440  85.693  145.300 1.00 185.88 ? 443 SER A OG  1 
ATOM   2210  N  N   . PHE A 1 445 ? 97.678  89.597  143.885 1.00 103.20 ? 444 PHE A N   1 
ATOM   2211  C  CA  . PHE A 1 445 ? 98.783  90.448  144.304 1.00 122.99 ? 444 PHE A CA  1 
ATOM   2212  C  C   . PHE A 1 445 ? 98.490  91.900  143.966 1.00 113.45 ? 444 PHE A C   1 
ATOM   2213  O  O   . PHE A 1 445 ? 98.606  92.760  144.840 1.00 194.60 ? 444 PHE A O   1 
ATOM   2214  C  CB  . PHE A 1 445 ? 100.108 90.034  143.656 1.00 114.67 ? 444 PHE A CB  1 
ATOM   2215  C  CG  . PHE A 1 445 ? 100.397 88.562  143.813 1.00 116.26 ? 444 PHE A CG  1 
ATOM   2216  C  CD1 . PHE A 1 445 ? 100.850 88.026  145.006 1.00 147.32 ? 444 PHE A CD1 1 
ATOM   2217  C  CD2 . PHE A 1 445 ? 100.190 87.698  142.769 1.00 114.75 ? 444 PHE A CD2 1 
ATOM   2218  C  CE1 . PHE A 1 445 ? 101.107 86.670  145.134 1.00 141.17 ? 444 PHE A CE1 1 
ATOM   2219  C  CE2 . PHE A 1 445 ? 100.445 86.337  142.892 1.00 143.82 ? 444 PHE A CE2 1 
ATOM   2220  C  CZ  . PHE A 1 445 ? 100.903 85.818  144.073 1.00 161.48 ? 444 PHE A CZ  1 
ATOM   2221  N  N   . LEU A 1 446 ? 98.129  92.168  142.723 1.00 70.41  ? 445 LEU A N   1 
ATOM   2222  C  CA  . LEU A 1 446 ? 97.814  93.523  142.337 1.00 111.67 ? 445 LEU A CA  1 
ATOM   2223  C  C   . LEU A 1 446 ? 96.461  94.053  142.840 1.00 143.11 ? 445 LEU A C   1 
ATOM   2224  O  O   . LEU A 1 446 ? 95.439  93.377  142.789 1.00 159.76 ? 445 LEU A O   1 
ATOM   2225  C  CB  . LEU A 1 446 ? 97.835  93.562  140.809 1.00 108.66 ? 445 LEU A CB  1 
ATOM   2226  C  CG  . LEU A 1 446 ? 99.225  93.342  140.229 1.00 109.32 ? 445 LEU A CG  1 
ATOM   2227  C  CD1 . LEU A 1 446 ? 99.229  93.660  138.773 1.00 91.26  ? 445 LEU A CD1 1 
ATOM   2228  C  CD2 . LEU A 1 446 ? 100.318 94.175  140.925 1.00 119.28 ? 445 LEU A CD2 1 
ATOM   2229  N  N   . PRO A 1 447 ? 96.404  95.336  143.270 1.00 105.23 ? 446 PRO A N   1 
ATOM   2230  C  CA  . PRO A 1 447 ? 95.140  96.051  143.376 1.00 136.52 ? 446 PRO A CA  1 
ATOM   2231  C  C   . PRO A 1 447 ? 94.676  96.463  141.976 1.00 128.82 ? 446 PRO A C   1 
ATOM   2232  O  O   . PRO A 1 447 ? 95.471  96.775  141.112 1.00 118.91 ? 446 PRO A O   1 
ATOM   2233  C  CB  . PRO A 1 447 ? 95.496  97.238  144.280 1.00 161.02 ? 446 PRO A CB  1 
ATOM   2234  C  CG  . PRO A 1 447 ? 96.933  97.546  143.928 1.00 143.06 ? 446 PRO A CG  1 
ATOM   2235  C  CD  . PRO A 1 447 ? 97.543  96.190  143.626 1.00 123.81 ? 446 PRO A CD  1 
ATOM   2236  N  N   . ALA A 1 448 ? 93.366  96.482  141.758 1.00 123.39 ? 447 ALA A N   1 
ATOM   2237  C  CA  . ALA A 1 448 ? 92.811  96.393  140.419 1.00 123.67 ? 447 ALA A CA  1 
ATOM   2238  C  C   . ALA A 1 448 ? 93.040  97.619  139.514 1.00 126.49 ? 447 ALA A C   1 
ATOM   2239  O  O   . ALA A 1 448 ? 92.753  97.490  138.322 1.00 179.48 ? 447 ALA A O   1 
ATOM   2240  C  CB  . ALA A 1 448 ? 91.336  96.113  140.536 1.00 198.13 ? 447 ALA A CB  1 
ATOM   2241  N  N   . GLN A 1 449 ? 93.546  98.766  140.008 1.00 137.89 ? 448 GLN A N   1 
ATOM   2242  C  CA  . GLN A 1 449 ? 93.933  99.874  139.125 1.00 161.34 ? 448 GLN A CA  1 
ATOM   2243  C  C   . GLN A 1 449 ? 95.211  99.577  138.329 1.00 140.19 ? 448 GLN A C   1 
ATOM   2244  O  O   . GLN A 1 449 ? 95.454  100.180 137.274 1.00 123.80 ? 448 GLN A O   1 
ATOM   2245  C  CB  . GLN A 1 449 ? 94.094  101.208 139.875 1.00 213.51 ? 448 GLN A CB  1 
ATOM   2246  C  CG  . GLN A 1 449 ? 95.318  101.406 140.786 1.00 155.50 ? 448 GLN A CG  1 
ATOM   2247  C  CD  . GLN A 1 449 ? 95.092  100.904 142.190 1.00 177.39 ? 448 GLN A CD  1 
ATOM   2248  O  OE1 . GLN A 1 449 ? 94.268  100.014 142.437 1.00 171.72 ? 448 GLN A OE1 1 
ATOM   2249  N  NE2 . GLN A 1 449 ? 95.841  101.481 143.120 1.00 216.20 ? 448 GLN A NE2 1 
ATOM   2250  N  N   . LEU A 1 450 ? 96.035  98.658  138.843 1.00 115.27 ? 449 LEU A N   1 
ATOM   2251  C  CA  . LEU A 1 450 ? 97.269  98.288  138.181 1.00 89.57  ? 449 LEU A CA  1 
ATOM   2252  C  C   . LEU A 1 450 ? 97.105  97.130  137.213 1.00 72.46  ? 449 LEU A C   1 
ATOM   2253  O  O   . LEU A 1 450 ? 98.005  96.991  136.425 1.00 72.72  ? 449 LEU A O   1 
ATOM   2254  C  CB  . LEU A 1 450 ? 98.263  97.854  139.250 1.00 81.03  ? 449 LEU A CB  1 
ATOM   2255  C  CG  . LEU A 1 450 ? 98.709  98.924  140.229 1.00 89.45  ? 449 LEU A CG  1 
ATOM   2256  C  CD1 . LEU A 1 450 ? 99.860  98.341  141.027 1.00 101.32 ? 449 LEU A CD1 1 
ATOM   2257  C  CD2 . LEU A 1 450 ? 99.127  100.241 139.538 1.00 95.84  ? 449 LEU A CD2 1 
ATOM   2258  N  N   . LEU A 1 451 ? 96.029  96.315  137.242 1.00 81.83  ? 450 LEU A N   1 
ATOM   2259  C  CA  . LEU A 1 451 ? 95.872  95.226  136.284 1.00 76.12  ? 450 LEU A CA  1 
ATOM   2260  C  C   . LEU A 1 451 ? 96.127  95.721  134.875 1.00 63.21  ? 450 LEU A C   1 
ATOM   2261  O  O   . LEU A 1 451 ? 96.885  95.014  134.175 1.00 64.06  ? 450 LEU A O   1 
ATOM   2262  C  CB  . LEU A 1 451 ? 94.513  94.531  136.324 1.00 75.03  ? 450 LEU A CB  1 
ATOM   2263  C  CG  . LEU A 1 451 ? 94.395  93.633  137.549 1.00 113.81 ? 450 LEU A CG  1 
ATOM   2264  C  CD1 . LEU A 1 451 ? 92.937  93.323  137.862 1.00 212.56 ? 450 LEU A CD1 1 
ATOM   2265  C  CD2 . LEU A 1 451 ? 95.105  92.323  137.341 1.00 115.62 ? 450 LEU A CD2 1 
ATOM   2266  N  N   . ARG A 1 452 ? 95.561  96.874  134.466 1.00 49.35  ? 451 ARG A N   1 
ATOM   2267  C  CA  . ARG A 1 452 ? 95.830  97.237  133.076 1.00 78.23  ? 451 ARG A CA  1 
ATOM   2268  C  C   . ARG A 1 452 ? 97.308  97.558  132.820 1.00 72.34  ? 451 ARG A C   1 
ATOM   2269  O  O   . ARG A 1 452 ? 97.905  97.239  131.776 1.00 51.84  ? 451 ARG A O   1 
ATOM   2270  C  CB  . ARG A 1 452 ? 94.944  98.378  132.619 1.00 104.38 ? 451 ARG A CB  1 
ATOM   2271  C  CG  . ARG A 1 452 ? 93.491  97.954  132.545 1.00 120.87 ? 451 ARG A CG  1 
ATOM   2272  C  CD  . ARG A 1 452 ? 92.697  99.147  132.185 1.00 140.66 ? 451 ARG A CD  1 
ATOM   2273  N  NE  . ARG A 1 452 ? 91.336  98.722  132.175 1.00 184.87 ? 451 ARG A NE  1 
ATOM   2274  C  CZ  . ARG A 1 452 ? 90.650  98.538  131.072 1.00 227.90 ? 451 ARG A CZ  1 
ATOM   2275  N  NH1 . ARG A 1 452 ? 89.345  98.388  131.218 1.00 312.31 ? 451 ARG A NH1 1 
ATOM   2276  N  NH2 . ARG A 1 452 ? 91.255  98.539  129.877 1.00 123.54 ? 451 ARG A NH2 1 
ATOM   2277  N  N   . LEU A 1 453 ? 97.873  98.196  133.829 1.00 71.06  ? 452 LEU A N   1 
ATOM   2278  C  CA  . LEU A 1 453 ? 99.224  98.677  133.719 1.00 62.39  ? 452 LEU A CA  1 
ATOM   2279  C  C   . LEU A 1 453 ? 100.213 97.549  133.660 1.00 52.40  ? 452 LEU A C   1 
ATOM   2280  O  O   . LEU A 1 453 ? 101.231 97.730  133.058 1.00 66.23  ? 452 LEU A O   1 
ATOM   2281  C  CB  . LEU A 1 453 ? 99.484  99.532  134.960 1.00 57.53  ? 452 LEU A CB  1 
ATOM   2282  C  CG  . LEU A 1 453 ? 100.686 100.458 134.834 1.00 79.53  ? 452 LEU A CG  1 
ATOM   2283  C  CD1 . LEU A 1 453 ? 100.668 101.295 133.582 1.00 94.12  ? 452 LEU A CD1 1 
ATOM   2284  C  CD2 . LEU A 1 453 ? 100.613 101.425 135.973 1.00 122.16 ? 452 LEU A CD2 1 
ATOM   2285  N  N   . TYR A 1 454 ? 99.953  96.433  134.350 1.00 65.77  ? 453 TYR A N   1 
ATOM   2286  C  CA  . TYR A 1 454 ? 100.838 95.280  134.341 1.00 62.89  ? 453 TYR A CA  1 
ATOM   2287  C  C   . TYR A 1 454 ? 100.650 94.531  133.036 1.00 70.60  ? 453 TYR A C   1 
ATOM   2288  O  O   . TYR A 1 454 ? 101.627 94.054  132.494 1.00 69.02  ? 453 TYR A O   1 
ATOM   2289  C  CB  . TYR A 1 454 ? 100.622 94.302  135.485 1.00 56.55  ? 453 TYR A CB  1 
ATOM   2290  C  CG  . TYR A 1 454 ? 101.601 94.624  136.584 1.00 55.89  ? 453 TYR A CG  1 
ATOM   2291  C  CD1 . TYR A 1 454 ? 101.518 95.751  137.312 1.00 67.66  ? 453 TYR A CD1 1 
ATOM   2292  C  CD2 . TYR A 1 454 ? 102.634 93.811  136.870 1.00 89.28  ? 453 TYR A CD2 1 
ATOM   2293  C  CE1 . TYR A 1 454 ? 102.400 96.076  138.325 1.00 77.36  ? 453 TYR A CE1 1 
ATOM   2294  C  CE2 . TYR A 1 454 ? 103.548 94.104  137.863 1.00 119.67 ? 453 TYR A CE2 1 
ATOM   2295  C  CZ  . TYR A 1 454 ? 103.431 95.249  138.603 1.00 94.47  ? 453 TYR A CZ  1 
ATOM   2296  O  OH  . TYR A 1 454 ? 104.294 95.544  139.589 1.00 96.16  ? 453 TYR A OH  1 
ATOM   2297  N  N   . GLN A 1 455 ? 99.433  94.453  132.517 1.00 76.93  ? 454 GLN A N   1 
ATOM   2298  C  CA  . GLN A 1 455 ? 99.250  93.756  131.251 1.00 89.10  ? 454 GLN A CA  1 
ATOM   2299  C  C   . GLN A 1 455 ? 100.000 94.450  130.145 1.00 61.36  ? 454 GLN A C   1 
ATOM   2300  O  O   . GLN A 1 455 ? 100.383 93.758  129.200 1.00 117.63 ? 454 GLN A O   1 
ATOM   2301  C  CB  . GLN A 1 455 ? 97.775  93.510  130.865 1.00 78.68  ? 454 GLN A CB  1 
ATOM   2302  C  CG  . GLN A 1 455 ? 97.343  92.402  131.815 1.00 112.01 ? 454 GLN A CG  1 
ATOM   2303  C  CD  . GLN A 1 455 ? 95.950  91.919  131.657 1.00 120.95 ? 454 GLN A CD  1 
ATOM   2304  O  OE1 . GLN A 1 455 ? 95.359  92.221  130.621 1.00 109.51 ? 454 GLN A OE1 1 
ATOM   2305  N  NE2 . GLN A 1 455 ? 95.482  91.189  132.682 1.00 134.99 ? 454 GLN A NE2 1 
ATOM   2306  N  N   . LEU A 1 456 ? 100.165 95.763  130.239 1.00 59.40  ? 455 LEU A N   1 
ATOM   2307  C  CA  . LEU A 1 456 ? 100.935 96.485  129.246 1.00 58.05  ? 455 LEU A CA  1 
ATOM   2308  C  C   . LEU A 1 456 ? 102.403 96.135  129.357 1.00 37.02  ? 455 LEU A C   1 
ATOM   2309  O  O   . LEU A 1 456 ? 103.088 96.212  128.368 1.00 37.53  ? 455 LEU A O   1 
ATOM   2310  C  CB  . LEU A 1 456 ? 100.634 97.979  129.389 1.00 59.29  ? 455 LEU A CB  1 
ATOM   2311  C  CG  . LEU A 1 456 ? 101.455 98.876  128.463 1.00 76.01  ? 455 LEU A CG  1 
ATOM   2312  C  CD1 . LEU A 1 456 ? 101.435 98.480  126.984 1.00 64.19  ? 455 LEU A CD1 1 
ATOM   2313  C  CD2 . LEU A 1 456 ? 100.976 100.321 128.567 1.00 91.38  ? 455 LEU A CD2 1 
ATOM   2314  N  N   . MET A 1 457 ? 102.849 95.792  130.553 1.00 43.74  ? 456 MET A N   1 
ATOM   2315  C  CA  . MET A 1 457 ? 104.268 95.640  130.843 1.00 48.95  ? 456 MET A CA  1 
ATOM   2316  C  C   . MET A 1 457 ? 104.649 94.172  130.592 1.00 55.87  ? 456 MET A C   1 
ATOM   2317  O  O   . MET A 1 457 ? 105.574 93.939  129.864 1.00 84.48  ? 456 MET A O   1 
ATOM   2318  C  CB  . MET A 1 457 ? 104.582 96.064  132.271 1.00 45.01  ? 456 MET A CB  1 
ATOM   2319  C  CG  . MET A 1 457 ? 106.027 95.884  132.607 1.00 60.09  ? 456 MET A CG  1 
ATOM   2320  S  SD  . MET A 1 457 ? 106.479 96.051  134.368 1.00 66.01  ? 456 MET A SD  1 
ATOM   2321  C  CE  . MET A 1 457 ? 105.939 94.502  135.054 1.00 58.31  ? 456 MET A CE  1 
ATOM   2322  N  N   . LEU A 1 458 ? 103.925 93.203  131.143 1.00 48.44  ? 457 LEU A N   1 
ATOM   2323  C  CA  . LEU A 1 458 ? 104.166 91.813  130.918 1.00 49.59  ? 457 LEU A CA  1 
ATOM   2324  C  C   . LEU A 1 458 ? 104.151 91.432  129.435 1.00 73.41  ? 457 LEU A C   1 
ATOM   2325  O  O   . LEU A 1 458 ? 104.890 90.549  128.998 1.00 128.63 ? 457 LEU A O   1 
ATOM   2326  C  CB  . LEU A 1 458 ? 103.137 91.044  131.752 1.00 58.93  ? 457 LEU A CB  1 
ATOM   2327  C  CG  . LEU A 1 458 ? 103.739 90.381  133.022 1.00 72.86  ? 457 LEU A CG  1 
ATOM   2328  C  CD1 . LEU A 1 458 ? 104.766 91.251  133.694 1.00 80.90  ? 457 LEU A CD1 1 
ATOM   2329  C  CD2 . LEU A 1 458 ? 102.633 90.061  133.993 1.00 77.45  ? 457 LEU A CD2 1 
ATOM   2330  N  N   . PHE A 1 459 ? 103.386 92.107  128.624 1.00 67.95  ? 458 PHE A N   1 
ATOM   2331  C  CA  . PHE A 1 459 ? 103.455 91.809  127.211 1.00 65.74  ? 458 PHE A CA  1 
ATOM   2332  C  C   . PHE A 1 459 ? 104.570 92.506  126.450 1.00 59.56  ? 458 PHE A C   1 
ATOM   2333  O  O   . PHE A 1 459 ? 104.604 92.326  125.237 1.00 146.69 ? 458 PHE A O   1 
ATOM   2334  C  CB  . PHE A 1 459 ? 102.103 92.132  126.570 1.00 75.05  ? 458 PHE A CB  1 
ATOM   2335  C  CG  . PHE A 1 459 ? 101.209 90.913  126.588 1.00 67.55  ? 458 PHE A CG  1 
ATOM   2336  C  CD1 . PHE A 1 459 ? 101.413 89.913  125.683 1.00 77.26  ? 458 PHE A CD1 1 
ATOM   2337  C  CD2 . PHE A 1 459 ? 100.201 90.753  127.512 1.00 62.18  ? 458 PHE A CD2 1 
ATOM   2338  C  CE1 . PHE A 1 459 ? 100.576 88.820  125.706 1.00 101.46 ? 458 PHE A CE1 1 
ATOM   2339  C  CE2 . PHE A 1 459 ? 99.379  89.659  127.549 1.00 55.52  ? 458 PHE A CE2 1 
ATOM   2340  C  CZ  . PHE A 1 459 ? 99.560  88.702  126.634 1.00 72.29  ? 458 PHE A CZ  1 
ATOM   2341  N  N   . THR A 1 460 ? 105.463 93.261  127.068 1.00 66.30  ? 459 THR A N   1 
ATOM   2342  C  CA  . THR A 1 460 ? 106.418 94.083  126.311 1.00 70.54  ? 459 THR A CA  1 
ATOM   2343  C  C   . THR A 1 460 ? 107.830 94.105  126.909 1.00 66.14  ? 459 THR A C   1 
ATOM   2344  O  O   . THR A 1 460 ? 108.715 94.765  126.364 1.00 76.95  ? 459 THR A O   1 
ATOM   2345  C  CB  . THR A 1 460 ? 105.896 95.507  126.039 1.00 60.29  ? 459 THR A CB  1 
ATOM   2346  O  OG1 . THR A 1 460 ? 106.009 96.191  127.264 1.00 59.52  ? 459 THR A OG1 1 
ATOM   2347  C  CG2 . THR A 1 460 ? 104.460 95.521  125.532 1.00 64.82  ? 459 THR A CG2 1 
ATOM   2348  N  N   . LEU A 1 461 ? 108.087 93.343  127.970 1.00 82.99  ? 460 LEU A N   1 
ATOM   2349  C  CA  . LEU A 1 461 ? 109.457 93.067  128.402 1.00 76.14  ? 460 LEU A CA  1 
ATOM   2350  C  C   . LEU A 1 461 ? 110.028 91.919  127.572 1.00 77.14  ? 460 LEU A C   1 
ATOM   2351  O  O   . LEU A 1 461 ? 109.274 91.131  127.015 1.00 73.01  ? 460 LEU A O   1 
ATOM   2352  C  CB  . LEU A 1 461 ? 109.509 92.721  129.890 1.00 53.44  ? 460 LEU A CB  1 
ATOM   2353  C  CG  . LEU A 1 461 ? 108.976 93.837  130.758 1.00 57.15  ? 460 LEU A CG  1 
ATOM   2354  C  CD1 . LEU A 1 461 ? 108.903 93.386  132.188 1.00 55.80  ? 460 LEU A CD1 1 
ATOM   2355  C  CD2 . LEU A 1 461 ? 109.822 95.085  130.535 1.00 59.40  ? 460 LEU A CD2 1 
ATOM   2356  N  N   . PRO A 1 462 ? 111.374 91.854  127.477 1.00 64.49  ? 461 PRO A N   1 
ATOM   2357  C  CA  . PRO A 1 462 ? 112.096 90.713  126.931 1.00 63.06  ? 461 PRO A CA  1 
ATOM   2358  C  C   . PRO A 1 462 ? 111.811 89.425  127.621 1.00 76.67  ? 461 PRO A C   1 
ATOM   2359  O  O   . PRO A 1 462 ? 112.126 89.339  128.810 1.00 81.59  ? 461 PRO A O   1 
ATOM   2360  C  CB  . PRO A 1 462 ? 113.530 90.980  127.411 1.00 93.60  ? 461 PRO A CB  1 
ATOM   2361  C  CG  . PRO A 1 462 ? 113.571 92.539  127.410 1.00 83.75  ? 461 PRO A CG  1 
ATOM   2362  C  CD  . PRO A 1 462 ? 112.256 92.943  127.931 1.00 58.76  ? 461 PRO A CD  1 
ATOM   2363  N  N   . GLY A 1 463 ? 111.192 88.467  126.911 1.00 92.35  ? 462 GLY A N   1 
ATOM   2364  C  CA  . GLY A 1 463 ? 110.840 87.211  127.576 1.00 80.93  ? 462 GLY A CA  1 
ATOM   2365  C  C   . GLY A 1 463 ? 109.416 86.764  127.373 1.00 49.66  ? 462 GLY A C   1 
ATOM   2366  O  O   . GLY A 1 463 ? 108.616 87.494  126.869 1.00 72.18  ? 462 GLY A O   1 
ATOM   2367  N  N   . THR A 1 464 ? 109.138 85.574  127.816 1.00 47.05  ? 463 THR A N   1 
ATOM   2368  C  CA  . THR A 1 464 ? 107.879 84.901  127.599 1.00 49.53  ? 463 THR A CA  1 
ATOM   2369  C  C   . THR A 1 464 ? 106.932 85.135  128.738 1.00 35.98  ? 463 THR A C   1 
ATOM   2370  O  O   . THR A 1 464 ? 107.079 84.480  129.724 1.00 46.05  ? 463 THR A O   1 
ATOM   2371  C  CB  . THR A 1 464 ? 108.162 83.401  127.550 1.00 59.18  ? 463 THR A CB  1 
ATOM   2372  O  OG1 . THR A 1 464 ? 108.985 83.208  126.383 1.00 56.59  ? 463 THR A OG1 1 
ATOM   2373  C  CG2 . THR A 1 464 ? 106.933 82.532  127.529 1.00 71.18  ? 463 THR A CG2 1 
ATOM   2374  N  N   . PRO A 1 465 ? 105.930 85.986  128.663 1.00 39.55  ? 464 PRO A N   1 
ATOM   2375  C  CA  . PRO A 1 465 ? 105.055 86.177  129.793 1.00 49.12  ? 464 PRO A CA  1 
ATOM   2376  C  C   . PRO A 1 465 ? 104.151 85.006  130.061 1.00 41.37  ? 464 PRO A C   1 
ATOM   2377  O  O   . PRO A 1 465 ? 103.835 84.246  129.168 1.00 49.38  ? 464 PRO A O   1 
ATOM   2378  C  CB  . PRO A 1 465 ? 104.178 87.355  129.306 1.00 65.31  ? 464 PRO A CB  1 
ATOM   2379  C  CG  . PRO A 1 465 ? 104.134 87.261  127.812 1.00 50.83  ? 464 PRO A CG  1 
ATOM   2380  C  CD  . PRO A 1 465 ? 105.530 86.774  127.519 1.00 45.24  ? 464 PRO A CD  1 
ATOM   2381  N  N   . VAL A 1 466 ? 103.697 84.906  131.281 1.00 44.94  ? 465 VAL A N   1 
ATOM   2382  C  CA  . VAL A 1 466 ? 102.866 83.792  131.689 1.00 71.75  ? 465 VAL A CA  1 
ATOM   2383  C  C   . VAL A 1 466 ? 101.694 84.292  132.546 1.00 73.80  ? 465 VAL A C   1 
ATOM   2384  O  O   . VAL A 1 466 ? 101.876 84.928  133.598 1.00 104.41 ? 465 VAL A O   1 
ATOM   2385  C  CB  . VAL A 1 466 ? 103.679 82.738  132.488 1.00 57.78  ? 465 VAL A CB  1 
ATOM   2386  C  CG1 . VAL A 1 466 ? 102.759 81.651  133.090 1.00 54.16  ? 465 VAL A CG1 1 
ATOM   2387  C  CG2 . VAL A 1 466 ? 104.822 82.179  131.687 1.00 44.34  ? 465 VAL A CG2 1 
ATOM   2388  N  N   . PHE A 1 467 ? 100.496 83.924  132.105 1.00 66.01  ? 466 PHE A N   1 
ATOM   2389  C  CA  . PHE A 1 467 ? 99.278  84.189  132.838 1.00 86.99  ? 466 PHE A CA  1 
ATOM   2390  C  C   . PHE A 1 467 ? 98.546  82.946  133.338 1.00 70.68  ? 466 PHE A C   1 
ATOM   2391  O  O   . PHE A 1 467 ? 98.577  81.915  132.709 1.00 86.70  ? 466 PHE A O   1 
ATOM   2392  C  CB  . PHE A 1 467 ? 98.390  84.944  131.890 1.00 77.50  ? 466 PHE A CB  1 
ATOM   2393  C  CG  . PHE A 1 467 ? 99.095  86.173  131.411 1.00 65.20  ? 466 PHE A CG  1 
ATOM   2394  C  CD1 . PHE A 1 467 ? 99.154  87.288  132.206 1.00 81.70  ? 466 PHE A CD1 1 
ATOM   2395  C  CD2 . PHE A 1 467 ? 99.640  86.222  130.167 1.00 67.58  ? 466 PHE A CD2 1 
ATOM   2396  C  CE1 . PHE A 1 467 ? 99.781  88.444  131.769 1.00 104.70 ? 466 PHE A CE1 1 
ATOM   2397  C  CE2 . PHE A 1 467 ? 100.241 87.377  129.729 1.00 91.53  ? 466 PHE A CE2 1 
ATOM   2398  C  CZ  . PHE A 1 467 ? 100.323 88.477  130.518 1.00 92.21  ? 466 PHE A CZ  1 
ATOM   2399  N  N   . SER A 1 468 ? 97.914  83.057  134.508 1.00 78.16  ? 467 SER A N   1 
ATOM   2400  C  CA  . SER A 1 468 ? 96.984  82.038  134.966 1.00 100.54 ? 467 SER A CA  1 
ATOM   2401  C  C   . SER A 1 468 ? 95.622  82.351  134.384 1.00 108.32 ? 467 SER A C   1 
ATOM   2402  O  O   . SER A 1 468 ? 95.376  83.475  133.916 1.00 123.50 ? 467 SER A O   1 
ATOM   2403  C  CB  . SER A 1 468 ? 96.929  81.913  136.451 1.00 117.00 ? 467 SER A CB  1 
ATOM   2404  O  OG  . SER A 1 468 ? 98.222  81.577  136.943 1.00 179.83 ? 467 SER A OG  1 
ATOM   2405  N  N   . TYR A 1 469 ? 94.723  81.368  134.448 1.00 92.93  ? 468 TYR A N   1 
ATOM   2406  C  CA  . TYR A 1 469 ? 93.536  81.517  133.617 1.00 93.18  ? 468 TYR A CA  1 
ATOM   2407  C  C   . TYR A 1 469 ? 92.671  82.614  134.195 1.00 86.70  ? 468 TYR A C   1 
ATOM   2408  O  O   . TYR A 1 469 ? 92.492  82.698  135.417 1.00 75.46  ? 468 TYR A O   1 
ATOM   2409  C  CB  . TYR A 1 469 ? 92.714  80.236  133.489 1.00 118.41 ? 468 TYR A CB  1 
ATOM   2410  C  CG  . TYR A 1 469 ? 92.144  79.702  134.778 1.00 99.57  ? 468 TYR A CG  1 
ATOM   2411  C  CD1 . TYR A 1 469 ? 92.902  78.904  135.614 1.00 117.46 ? 468 TYR A CD1 1 
ATOM   2412  C  CD2 . TYR A 1 469 ? 90.860  80.027  135.139 1.00 85.32  ? 468 TYR A CD2 1 
ATOM   2413  C  CE1 . TYR A 1 469 ? 92.389  78.418  136.798 1.00 145.97 ? 468 TYR A CE1 1 
ATOM   2414  C  CE2 . TYR A 1 469 ? 90.342  79.562  136.329 1.00 124.81 ? 468 TYR A CE2 1 
ATOM   2415  C  CZ  . TYR A 1 469 ? 91.101  78.753  137.158 1.00 144.28 ? 468 TYR A CZ  1 
ATOM   2416  O  OH  . TYR A 1 469 ? 90.582  78.292  138.327 1.00 186.03 ? 468 TYR A OH  1 
ATOM   2417  N  N   . GLY A 1 470 ? 92.161  83.464  133.316 1.00 79.96  ? 469 GLY A N   1 
ATOM   2418  C  CA  . GLY A 1 470 ? 91.287  84.521  133.782 1.00 113.38 ? 469 GLY A CA  1 
ATOM   2419  C  C   . GLY A 1 470 ? 92.010  85.796  134.181 1.00 88.80  ? 469 GLY A C   1 
ATOM   2420  O  O   . GLY A 1 470 ? 91.345  86.773  134.476 1.00 146.41 ? 469 GLY A O   1 
ATOM   2421  N  N   . ASP A 1 471 ? 93.341  85.811  134.180 1.00 120.66 ? 470 ASP A N   1 
ATOM   2422  C  CA  . ASP A 1 471 ? 94.085  87.063  134.259 1.00 131.54 ? 470 ASP A CA  1 
ATOM   2423  C  C   . ASP A 1 471 ? 93.633  87.999  133.146 1.00 91.33  ? 470 ASP A C   1 
ATOM   2424  O  O   . ASP A 1 471 ? 93.572  89.212  133.366 1.00 123.04 ? 470 ASP A O   1 
ATOM   2425  C  CB  . ASP A 1 471 ? 95.602  86.842  134.215 1.00 116.07 ? 470 ASP A CB  1 
ATOM   2426  C  CG  . ASP A 1 471 ? 96.124  86.194  135.497 1.00 207.16 ? 470 ASP A CG  1 
ATOM   2427  O  OD1 . ASP A 1 471 ? 95.488  86.364  136.613 1.00 173.81 ? 470 ASP A OD1 1 
ATOM   2428  O  OD2 . ASP A 1 471 ? 97.181  85.522  135.399 1.00 246.79 ? 470 ASP A OD2 1 
ATOM   2429  N  N   . GLU A 1 472 ? 93.288  87.416  131.999 1.00 63.51  ? 471 GLU A N   1 
ATOM   2430  C  CA  . GLU A 1 472 ? 92.968  88.180  130.807 1.00 82.13  ? 471 GLU A CA  1 
ATOM   2431  C  C   . GLU A 1 472 ? 91.623  88.893  131.005 1.00 120.45 ? 471 GLU A C   1 
ATOM   2432  O  O   . GLU A 1 472 ? 91.280  89.735  130.183 1.00 87.41  ? 471 GLU A O   1 
ATOM   2433  C  CB  . GLU A 1 472 ? 93.043  87.297  129.539 1.00 68.98  ? 471 GLU A CB  1 
ATOM   2434  C  CG  . GLU A 1 472 ? 91.924  86.284  129.408 1.00 114.73 ? 471 GLU A CG  1 
ATOM   2435  C  CD  . GLU A 1 472 ? 91.919  85.036  130.273 1.00 143.55 ? 471 GLU A CD  1 
ATOM   2436  O  OE1 . GLU A 1 472 ? 92.686  84.980  131.190 1.00 147.99 ? 471 GLU A OE1 1 
ATOM   2437  O  OE2 . GLU A 1 472 ? 91.155  84.104  130.000 1.00 175.84 ? 471 GLU A OE2 1 
ATOM   2438  N  N   . ILE A 1 473 ? 90.838  88.536  132.041 1.00 120.20 ? 472 ILE A N   1 
ATOM   2439  C  CA  . ILE A 1 473 ? 89.586  89.228  132.344 1.00 127.77 ? 472 ILE A CA  1 
ATOM   2440  C  C   . ILE A 1 473 ? 89.592  89.878  133.727 1.00 124.52 ? 472 ILE A C   1 
ATOM   2441  O  O   . ILE A 1 473 ? 88.560  90.373  134.186 1.00 135.18 ? 472 ILE A O   1 
ATOM   2442  C  CB  . ILE A 1 473 ? 88.409  88.240  132.263 1.00 125.15 ? 472 ILE A CB  1 
ATOM   2443  C  CG1 . ILE A 1 473 ? 88.470  87.151  133.339 1.00 107.12 ? 472 ILE A CG1 1 
ATOM   2444  C  CG2 . ILE A 1 473 ? 88.324  87.671  130.873 1.00 126.02 ? 472 ILE A CG2 1 
ATOM   2445  C  CD1 . ILE A 1 473 ? 87.217  86.418  133.591 1.00 130.41 ? 472 ILE A CD1 1 
ATOM   2446  N  N   . GLY A 1 474 ? 90.730  89.883  134.406 1.00 131.04 ? 473 GLY A N   1 
ATOM   2447  C  CA  . GLY A 1 474 ? 90.780  90.397  135.755 1.00 126.55 ? 473 GLY A CA  1 
ATOM   2448  C  C   . GLY A 1 474 ? 89.890  89.623  136.721 1.00 104.10 ? 473 GLY A C   1 
ATOM   2449  O  O   . GLY A 1 474 ? 89.276  90.225  137.600 1.00 180.59 ? 473 GLY A O   1 
ATOM   2450  N  N   . LEU A 1 475 ? 89.833  88.308  136.576 1.00 115.76 ? 474 LEU A N   1 
ATOM   2451  C  CA  . LEU A 1 475 ? 89.144  87.474  137.537 1.00 146.00 ? 474 LEU A CA  1 
ATOM   2452  C  C   . LEU A 1 475 ? 89.771  87.703  138.929 1.00 153.00 ? 474 LEU A C   1 
ATOM   2453  O  O   . LEU A 1 475 ? 90.946  88.059  139.057 1.00 176.41 ? 474 LEU A O   1 
ATOM   2454  C  CB  . LEU A 1 475 ? 89.279  86.029  137.029 1.00 123.15 ? 474 LEU A CB  1 
ATOM   2455  C  CG  . LEU A 1 475 ? 88.828  84.892  137.953 1.00 134.74 ? 474 LEU A CG  1 
ATOM   2456  C  CD1 . LEU A 1 475 ? 87.361  84.958  138.365 1.00 200.52 ? 474 LEU A CD1 1 
ATOM   2457  C  CD2 . LEU A 1 475 ? 89.059  83.580  137.240 1.00 118.56 ? 474 LEU A CD2 1 
ATOM   2458  N  N   . ASP A 1 476 ? 88.993  87.476  139.999 1.00 150.13 ? 475 ASP A N   1 
ATOM   2459  C  CA  . ASP A 1 476 ? 89.480  87.617  141.363 1.00 172.10 ? 475 ASP A CA  1 
ATOM   2460  C  C   . ASP A 1 476 ? 88.747  86.623  142.260 1.00 150.31 ? 475 ASP A C   1 
ATOM   2461  O  O   . ASP A 1 476 ? 87.511  86.601  142.275 1.00 161.43 ? 475 ASP A O   1 
ATOM   2462  C  CB  . ASP A 1 476 ? 89.276  89.054  141.853 1.00 246.09 ? 475 ASP A CB  1 
ATOM   2463  C  CG  . ASP A 1 476 ? 89.655  89.320  143.310 1.00 322.63 ? 475 ASP A CG  1 
ATOM   2464  O  OD1 . ASP A 1 476 ? 90.153  88.386  144.001 1.00 261.53 ? 475 ASP A OD1 1 
ATOM   2465  O  OD2 . ASP A 1 476 ? 89.455  90.471  143.755 1.00 382.17 ? 475 ASP A OD2 1 
ATOM   2466  N  N   . ALA A 1 477 ? 89.504  85.829  143.029 1.00 147.04 ? 476 ALA A N   1 
ATOM   2467  C  CA  . ALA A 1 477 ? 88.895  84.795  143.854 1.00 224.40 ? 476 ALA A CA  1 
ATOM   2468  C  C   . ALA A 1 477 ? 88.007  85.398  144.951 1.00 209.89 ? 476 ALA A C   1 
ATOM   2469  O  O   . ALA A 1 477 ? 87.022  84.758  145.347 1.00 278.89 ? 476 ALA A O   1 
ATOM   2470  C  CB  . ALA A 1 477 ? 89.961  83.896  144.425 1.00 265.53 ? 476 ALA A CB  1 
ATOM   2471  N  N   . ALA A 1 478 ? 88.334  86.616  145.420 1.00 163.51 ? 477 ALA A N   1 
ATOM   2472  C  CA  . ALA A 1 478 ? 87.615  87.239  146.529 1.00 195.24 ? 477 ALA A CA  1 
ATOM   2473  C  C   . ALA A 1 478 ? 86.243  87.799  146.125 1.00 195.51 ? 477 ALA A C   1 
ATOM   2474  O  O   . ALA A 1 478 ? 85.365  87.926  146.987 1.00 209.26 ? 477 ALA A O   1 
ATOM   2475  C  CB  . ALA A 1 478 ? 88.480  88.320  147.132 1.00 235.24 ? 477 ALA A CB  1 
ATOM   2476  N  N   . ALA A 1 479 ? 86.050  88.134  144.834 1.00 206.37 ? 478 ALA A N   1 
ATOM   2477  C  CA  . ALA A 1 479 ? 84.893  88.905  144.378 1.00 190.28 ? 478 ALA A CA  1 
ATOM   2478  C  C   . ALA A 1 479 ? 83.576  88.124  144.484 1.00 199.39 ? 478 ALA A C   1 
ATOM   2479  O  O   . ALA A 1 479 ? 82.526  88.752  144.673 1.00 280.30 ? 478 ALA A O   1 
ATOM   2480  C  CB  . ALA A 1 479 ? 85.127  89.371  142.957 1.00 217.46 ? 478 ALA A CB  1 
ATOM   2481  N  N   . LEU A 1 480 ? 83.648  86.784  144.351 1.00 198.15 ? 479 LEU A N   1 
ATOM   2482  C  CA  . LEU A 1 480 ? 82.538  85.851  144.505 1.00 252.07 ? 479 LEU A CA  1 
ATOM   2483  C  C   . LEU A 1 480 ? 82.871  84.929  145.683 1.00 242.10 ? 479 LEU A C   1 
ATOM   2484  O  O   . LEU A 1 480 ? 83.479  83.883  145.478 1.00 243.10 ? 479 LEU A O   1 
ATOM   2485  C  CB  . LEU A 1 480 ? 82.365  85.090  143.186 1.00 288.42 ? 479 LEU A CB  1 
ATOM   2486  C  CG  . LEU A 1 480 ? 81.374  85.669  142.171 1.00 268.95 ? 479 LEU A CG  1 
ATOM   2487  C  CD1 . LEU A 1 480 ? 81.609  87.124  141.853 1.00 252.13 ? 479 LEU A CD1 1 
ATOM   2488  C  CD2 . LEU A 1 480 ? 81.453  84.885  140.885 1.00 277.76 ? 479 LEU A CD2 1 
ATOM   2489  N  N   . PRO A 1 481 ? 82.522  85.314  146.937 1.00 275.74 ? 480 PRO A N   1 
ATOM   2490  C  CA  . PRO A 1 481 ? 83.052  84.666  148.146 1.00 333.70 ? 480 PRO A CA  1 
ATOM   2491  C  C   . PRO A 1 481 ? 82.851  83.158  148.292 1.00 318.10 ? 480 PRO A C   1 
ATOM   2492  O  O   . PRO A 1 481 ? 81.869  82.601  147.792 1.00 265.76 ? 480 PRO A O   1 
ATOM   2493  C  CB  . PRO A 1 481 ? 82.311  85.406  149.283 1.00 375.66 ? 480 PRO A CB  1 
ATOM   2494  C  CG  . PRO A 1 481 ? 81.984  86.754  148.699 1.00 347.77 ? 480 PRO A CG  1 
ATOM   2495  C  CD  . PRO A 1 481 ? 81.637  86.447  147.262 1.00 275.41 ? 480 PRO A CD  1 
ATOM   2496  N  N   . GLY A 1 482 ? 83.824  82.535  148.985 1.00 300.94 ? 481 GLY A N   1 
ATOM   2497  C  CA  . GLY A 1 482 ? 83.755  81.148  149.424 1.00 325.65 ? 481 GLY A CA  1 
ATOM   2498  C  C   . GLY A 1 482 ? 84.614  80.187  148.598 1.00 348.67 ? 481 GLY A C   1 
ATOM   2499  O  O   . GLY A 1 482 ? 85.113  79.200  149.146 1.00 336.87 ? 481 GLY A O   1 
ATOM   2500  N  N   . GLN A 1 483 ? 84.774  80.466  147.291 1.00 337.90 ? 482 GLN A N   1 
ATOM   2501  C  CA  . GLN A 1 483 ? 85.555  79.634  146.381 1.00 286.67 ? 482 GLN A CA  1 
ATOM   2502  C  C   . GLN A 1 483 ? 87.041  79.688  146.754 1.00 313.31 ? 482 GLN A C   1 
ATOM   2503  O  O   . GLN A 1 483 ? 87.520  80.699  147.283 1.00 313.33 ? 482 GLN A O   1 
ATOM   2504  C  CB  . GLN A 1 483 ? 85.324  80.067  144.926 1.00 253.15 ? 482 GLN A CB  1 
ATOM   2505  C  CG  . GLN A 1 483 ? 85.885  81.445  144.601 1.00 264.34 ? 482 GLN A CG  1 
ATOM   2506  C  CD  . GLN A 1 483 ? 85.621  81.923  143.195 1.00 284.57 ? 482 GLN A CD  1 
ATOM   2507  O  OE1 . GLN A 1 483 ? 85.419  81.136  142.277 1.00 175.60 ? 482 GLN A OE1 1 
ATOM   2508  N  NE2 . GLN A 1 483 ? 85.633  83.237  143.023 1.00 327.26 ? 482 GLN A NE2 1 
ATOM   2509  N  N   . PRO A 1 484 ? 87.821  78.609  146.487 1.00 334.22 ? 483 PRO A N   1 
ATOM   2510  C  CA  . PRO A 1 484 ? 89.218  78.555  146.919 1.00 339.48 ? 483 PRO A CA  1 
ATOM   2511  C  C   . PRO A 1 484 ? 90.146  79.432  146.071 1.00 292.42 ? 483 PRO A C   1 
ATOM   2512  O  O   . PRO A 1 484 ? 90.013  79.523  144.846 1.00 225.30 ? 483 PRO A O   1 
ATOM   2513  C  CB  . PRO A 1 484 ? 89.562  77.063  146.775 1.00 345.34 ? 483 PRO A CB  1 
ATOM   2514  C  CG  . PRO A 1 484 ? 88.696  76.598  145.629 1.00 341.63 ? 483 PRO A CG  1 
ATOM   2515  C  CD  . PRO A 1 484 ? 87.414  77.389  145.765 1.00 317.80 ? 483 PRO A CD  1 
ATOM   2516  N  N   . MET A 1 485 ? 91.112  80.058  146.743 1.00 278.52 ? 484 MET A N   1 
ATOM   2517  C  CA  . MET A 1 485 ? 92.113  80.878  146.077 1.00 311.23 ? 484 MET A CA  1 
ATOM   2518  C  C   . MET A 1 485 ? 93.070  80.056  145.201 1.00 304.62 ? 484 MET A C   1 
ATOM   2519  O  O   . MET A 1 485 ? 93.820  80.651  144.427 1.00 330.50 ? 484 MET A O   1 
ATOM   2520  C  CB  . MET A 1 485 ? 92.909  81.665  147.126 1.00 372.75 ? 484 MET A CB  1 
ATOM   2521  C  CG  . MET A 1 485 ? 92.057  82.699  147.849 1.00 409.88 ? 484 MET A CG  1 
ATOM   2522  S  SD  . MET A 1 485 ? 93.028  84.099  148.487 1.00 421.07 ? 484 MET A SD  1 
ATOM   2523  C  CE  . MET A 1 485 ? 94.278  83.227  149.430 1.00 430.28 ? 484 MET A CE  1 
ATOM   2524  N  N   . GLU A 1 486 ? 93.053  78.716  145.318 1.00 279.81 ? 485 GLU A N   1 
ATOM   2525  C  CA  . GLU A 1 486 ? 93.738  77.804  144.409 1.00 323.74 ? 485 GLU A CA  1 
ATOM   2526  C  C   . GLU A 1 486 ? 93.132  77.771  142.995 1.00 289.28 ? 485 GLU A C   1 
ATOM   2527  O  O   . GLU A 1 486 ? 93.877  77.611  142.021 1.00 307.04 ? 485 GLU A O   1 
ATOM   2528  C  CB  . GLU A 1 486 ? 93.712  76.401  145.029 1.00 395.85 ? 485 GLU A CB  1 
ATOM   2529  C  CG  . GLU A 1 486 ? 94.404  75.322  144.205 1.00 481.13 ? 485 GLU A CG  1 
ATOM   2530  C  CD  . GLU A 1 486 ? 94.594  73.976  144.891 1.00 526.24 ? 485 GLU A CD  1 
ATOM   2531  O  OE1 . GLU A 1 486 ? 94.095  73.792  146.024 1.00 533.23 ? 485 GLU A OE1 1 
ATOM   2532  O  OE2 . GLU A 1 486 ? 95.247  73.104  144.285 1.00 534.67 ? 485 GLU A OE2 1 
ATOM   2533  N  N   . ALA A 1 487 ? 91.801  77.894  142.876 1.00 216.26 ? 486 ALA A N   1 
ATOM   2534  C  CA  . ALA A 1 487 ? 91.091  77.459  141.681 1.00 172.62 ? 486 ALA A CA  1 
ATOM   2535  C  C   . ALA A 1 487 ? 89.716  78.136  141.572 1.00 149.65 ? 486 ALA A C   1 
ATOM   2536  O  O   . ALA A 1 487 ? 88.665  77.497  141.683 1.00 177.15 ? 486 ALA A O   1 
ATOM   2537  C  CB  . ALA A 1 487 ? 90.982  75.947  141.724 1.00 231.75 ? 486 ALA A CB  1 
ATOM   2538  N  N   . PRO A 1 488 ? 89.658  79.460  141.338 1.00 112.11 ? 487 PRO A N   1 
ATOM   2539  C  CA  . PRO A 1 488 ? 88.396  80.184  141.196 1.00 139.98 ? 487 PRO A CA  1 
ATOM   2540  C  C   . PRO A 1 488 ? 87.694  79.877  139.882 1.00 130.96 ? 487 PRO A C   1 
ATOM   2541  O  O   . PRO A 1 488 ? 88.360  79.645  138.880 1.00 105.52 ? 487 PRO A O   1 
ATOM   2542  C  CB  . PRO A 1 488 ? 88.785  81.662  141.213 1.00 137.10 ? 487 PRO A CB  1 
ATOM   2543  C  CG  . PRO A 1 488 ? 90.134  81.613  140.653 1.00 125.74 ? 487 PRO A CG  1 
ATOM   2544  C  CD  . PRO A 1 488 ? 90.787  80.349  141.189 1.00 136.19 ? 487 PRO A CD  1 
ATOM   2545  N  N   . VAL A 1 489 ? 86.348  79.874  139.928 1.00 162.38 ? 488 VAL A N   1 
ATOM   2546  C  CA  . VAL A 1 489 ? 85.513  79.448  138.816 1.00 155.16 ? 488 VAL A CA  1 
ATOM   2547  C  C   . VAL A 1 489 ? 85.489  80.553  137.783 1.00 119.57 ? 488 VAL A C   1 
ATOM   2548  O  O   . VAL A 1 489 ? 85.204  81.702  138.146 1.00 93.59  ? 488 VAL A O   1 
ATOM   2549  C  CB  . VAL A 1 489 ? 84.068  79.132  139.228 1.00 212.30 ? 488 VAL A CB  1 
ATOM   2550  C  CG1 . VAL A 1 489 ? 83.204  78.784  138.005 1.00 244.34 ? 488 VAL A CG1 1 
ATOM   2551  C  CG2 . VAL A 1 489 ? 84.027  78.039  140.294 1.00 231.88 ? 488 VAL A CG2 1 
ATOM   2552  N  N   . MET A 1 490 ? 85.771  80.160  136.525 1.00 94.68  ? 489 MET A N   1 
ATOM   2553  C  CA  . MET A 1 490 ? 86.003  81.127  135.472 1.00 104.88 ? 489 MET A CA  1 
ATOM   2554  C  C   . MET A 1 490 ? 84.633  81.641  135.037 1.00 108.13 ? 489 MET A C   1 
ATOM   2555  O  O   . MET A 1 490 ? 83.700  80.837  134.882 1.00 140.09 ? 489 MET A O   1 
ATOM   2556  C  CB  . MET A 1 490 ? 86.777  80.460  134.326 1.00 134.40 ? 489 MET A CB  1 
ATOM   2557  C  CG  . MET A 1 490 ? 86.906  81.247  133.033 1.00 152.47 ? 489 MET A CG  1 
ATOM   2558  S  SD  . MET A 1 490 ? 87.758  82.723  133.205 1.00 131.04 ? 489 MET A SD  1 
ATOM   2559  C  CE  . MET A 1 490 ? 88.208  83.099  131.506 1.00 123.07 ? 489 MET A CE  1 
ATOM   2560  N  N   . LEU A 1 491 ? 84.511  82.967  134.828 1.00 93.70  ? 490 LEU A N   1 
ATOM   2561  C  CA  . LEU A 1 491 ? 83.227  83.592  134.493 1.00 125.69 ? 490 LEU A CA  1 
ATOM   2562  C  C   . LEU A 1 491 ? 83.075  83.826  132.976 1.00 137.24 ? 490 LEU A C   1 
ATOM   2563  O  O   . LEU A 1 491 ? 83.346  84.902  132.431 1.00 74.78  ? 490 LEU A O   1 
ATOM   2564  C  CB  . LEU A 1 491 ? 83.026  84.890  135.279 1.00 97.52  ? 490 LEU A CB  1 
ATOM   2565  C  CG  . LEU A 1 491 ? 83.256  84.781  136.775 1.00 155.59 ? 490 LEU A CG  1 
ATOM   2566  C  CD1 . LEU A 1 491 ? 82.979  86.139  137.404 1.00 235.46 ? 490 LEU A CD1 1 
ATOM   2567  C  CD2 . LEU A 1 491 ? 82.391  83.706  137.431 1.00 171.28 ? 490 LEU A CD2 1 
ATOM   2568  N  N   . TRP A 1 492 ? 82.578  82.805  132.284 1.00 130.65 ? 491 TRP A N   1 
ATOM   2569  C  CA  . TRP A 1 492 ? 82.324  82.899  130.862 1.00 128.83 ? 491 TRP A CA  1 
ATOM   2570  C  C   . TRP A 1 492 ? 81.170  83.833  130.516 1.00 179.10 ? 491 TRP A C   1 
ATOM   2571  O  O   . TRP A 1 492 ? 81.312  84.678  129.644 1.00 185.60 ? 491 TRP A O   1 
ATOM   2572  C  CB  . TRP A 1 492 ? 82.011  81.507  130.373 1.00 150.80 ? 491 TRP A CB  1 
ATOM   2573  C  CG  . TRP A 1 492 ? 83.185  80.611  130.589 1.00 152.41 ? 491 TRP A CG  1 
ATOM   2574  C  CD1 . TRP A 1 492 ? 83.351  79.681  131.570 1.00 143.92 ? 491 TRP A CD1 1 
ATOM   2575  C  CD2 . TRP A 1 492 ? 84.359  80.588  129.755 1.00 172.73 ? 491 TRP A CD2 1 
ATOM   2576  N  NE1 . TRP A 1 492 ? 84.568  79.072  131.398 1.00 156.28 ? 491 TRP A NE1 1 
ATOM   2577  C  CE2 . TRP A 1 492 ? 85.206  79.603  130.305 1.00 164.07 ? 491 TRP A CE2 1 
ATOM   2578  C  CE3 . TRP A 1 492 ? 84.756  81.295  128.607 1.00 148.87 ? 491 TRP A CE3 1 
ATOM   2579  C  CZ2 . TRP A 1 492 ? 86.438  79.321  129.734 1.00 156.55 ? 491 TRP A CZ2 1 
ATOM   2580  C  CZ3 . TRP A 1 492 ? 85.971  81.017  128.036 1.00 118.26 ? 491 TRP A CZ3 1 
ATOM   2581  C  CH2 . TRP A 1 492 ? 86.797  80.044  128.608 1.00 177.13 ? 491 TRP A CH2 1 
ATOM   2582  N  N   . ASP A 1 493 ? 80.040  83.670  131.214 1.00 201.16 ? 492 ASP A N   1 
ATOM   2583  C  CA  . ASP A 1 493 ? 78.840  84.484  131.039 1.00 235.69 ? 492 ASP A CA  1 
ATOM   2584  C  C   . ASP A 1 493 ? 78.073  84.526  132.365 1.00 245.31 ? 492 ASP A C   1 
ATOM   2585  O  O   . ASP A 1 493 ? 78.477  83.866  133.320 1.00 191.91 ? 492 ASP A O   1 
ATOM   2586  C  CB  . ASP A 1 493 ? 77.981  83.914  129.903 1.00 292.61 ? 492 ASP A CB  1 
ATOM   2587  C  CG  . ASP A 1 493 ? 77.385  82.539  130.198 1.00 297.21 ? 492 ASP A CG  1 
ATOM   2588  O  OD1 . ASP A 1 493 ? 76.615  82.441  131.173 1.00 233.48 ? 492 ASP A OD1 1 
ATOM   2589  O  OD2 . ASP A 1 493 ? 77.695  81.576  129.460 1.00 299.09 ? 492 ASP A OD2 1 
ATOM   2590  N  N   . GLU A 1 494 ? 76.952  85.268  132.428 1.00 248.25 ? 493 GLU A N   1 
ATOM   2591  C  CA  . GLU A 1 494 ? 76.265  85.557  133.690 1.00 238.55 ? 493 GLU A CA  1 
ATOM   2592  C  C   . GLU A 1 494 ? 75.763  84.314  134.441 1.00 207.13 ? 493 GLU A C   1 
ATOM   2593  O  O   . GLU A 1 494 ? 75.470  84.430  135.642 1.00 186.13 ? 493 GLU A O   1 
ATOM   2594  C  CB  . GLU A 1 494 ? 75.133  86.556  133.439 1.00 242.73 ? 493 GLU A CB  1 
ATOM   2595  C  CG  . GLU A 1 494 ? 75.653  87.944  133.085 1.00 259.37 ? 493 GLU A CG  1 
ATOM   2596  C  CD  . GLU A 1 494 ? 74.604  89.036  132.964 1.00 340.19 ? 493 GLU A CD  1 
ATOM   2597  O  OE1 . GLU A 1 494 ? 73.962  89.352  133.984 1.00 309.93 ? 493 GLU A OE1 1 
ATOM   2598  O  OE2 . GLU A 1 494 ? 74.440  89.581  131.846 1.00 425.86 ? 493 GLU A OE2 1 
ATOM   2599  N  N   . SER A 1 495 ? 75.678  83.155  133.764 1.00 190.65 ? 494 SER A N   1 
ATOM   2600  C  CA  . SER A 1 495 ? 75.334  81.889  134.413 1.00 259.35 ? 494 SER A CA  1 
ATOM   2601  C  C   . SER A 1 495 ? 76.434  81.292  135.301 1.00 225.51 ? 494 SER A C   1 
ATOM   2602  O  O   . SER A 1 495 ? 76.121  80.463  136.157 1.00 194.93 ? 494 SER A O   1 
ATOM   2603  C  CB  . SER A 1 495 ? 74.954  80.866  133.377 1.00 293.60 ? 494 SER A CB  1 
ATOM   2604  O  OG  . SER A 1 495 ? 76.092  80.426  132.648 1.00 245.44 ? 494 SER A OG  1 
ATOM   2605  N  N   . SER A 1 496 ? 77.698  81.696  135.092 1.00 226.55 ? 495 SER A N   1 
ATOM   2606  C  CA  . SER A 1 496 ? 78.862  80.851  135.346 1.00 226.75 ? 495 SER A CA  1 
ATOM   2607  C  C   . SER A 1 496 ? 79.092  80.536  136.825 1.00 230.09 ? 495 SER A C   1 
ATOM   2608  O  O   . SER A 1 496 ? 79.751  79.527  137.103 1.00 258.37 ? 495 SER A O   1 
ATOM   2609  C  CB  . SER A 1 496 ? 80.100  81.465  134.748 1.00 181.27 ? 495 SER A CB  1 
ATOM   2610  O  OG  . SER A 1 496 ? 79.928  81.739  133.366 1.00 129.47 ? 495 SER A OG  1 
ATOM   2611  N  N   . PHE A 1 497 ? 78.572  81.369  137.752 1.00 201.88 ? 496 PHE A N   1 
ATOM   2612  C  CA  . PHE A 1 497 ? 78.619  81.080  139.184 1.00 223.98 ? 496 PHE A CA  1 
ATOM   2613  C  C   . PHE A 1 497 ? 77.202  81.065  139.727 1.00 218.74 ? 496 PHE A C   1 
ATOM   2614  O  O   . PHE A 1 497 ? 76.750  82.048  140.311 1.00 230.90 ? 496 PHE A O   1 
ATOM   2615  C  CB  . PHE A 1 497 ? 79.486  82.098  139.910 1.00 226.18 ? 496 PHE A CB  1 
ATOM   2616  C  CG  . PHE A 1 497 ? 79.787  81.845  141.369 1.00 216.97 ? 496 PHE A CG  1 
ATOM   2617  C  CD1 . PHE A 1 497 ? 80.693  80.864  141.770 1.00 226.23 ? 496 PHE A CD1 1 
ATOM   2618  C  CD2 . PHE A 1 497 ? 79.184  82.613  142.355 1.00 261.09 ? 496 PHE A CD2 1 
ATOM   2619  C  CE1 . PHE A 1 497 ? 80.985  80.651  143.116 1.00 219.60 ? 496 PHE A CE1 1 
ATOM   2620  C  CE2 . PHE A 1 497 ? 79.479  82.405  143.704 1.00 286.71 ? 496 PHE A CE2 1 
ATOM   2621  C  CZ  . PHE A 1 497 ? 80.377  81.422  144.085 1.00 224.96 ? 496 PHE A CZ  1 
ATOM   2622  N  N   . PRO A 1 498 ? 76.471  79.940  139.540 1.00 267.49 ? 497 PRO A N   1 
ATOM   2623  C  CA  . PRO A 1 498 ? 75.056  79.872  139.896 1.00 311.06 ? 497 PRO A CA  1 
ATOM   2624  C  C   . PRO A 1 498 ? 74.795  79.673  141.392 1.00 324.98 ? 497 PRO A C   1 
ATOM   2625  O  O   . PRO A 1 498 ? 73.642  79.786  141.800 1.00 358.00 ? 497 PRO A O   1 
ATOM   2626  C  CB  . PRO A 1 498 ? 74.581  78.664  139.071 1.00 324.93 ? 497 PRO A CB  1 
ATOM   2627  C  CG  . PRO A 1 498 ? 75.776  77.740  139.073 1.00 320.63 ? 497 PRO A CG  1 
ATOM   2628  C  CD  . PRO A 1 498 ? 76.965  78.670  138.980 1.00 290.06 ? 497 PRO A CD  1 
ATOM   2629  N  N   . ASP A 1 499 ? 75.844  79.398  142.194 1.00 275.54 ? 498 ASP A N   1 
ATOM   2630  C  CA  . ASP A 1 499 ? 75.715  79.077  143.615 1.00 289.40 ? 498 ASP A CA  1 
ATOM   2631  C  C   . ASP A 1 499 ? 75.226  80.270  144.460 1.00 264.86 ? 498 ASP A C   1 
ATOM   2632  O  O   . ASP A 1 499 ? 74.705  80.064  145.559 1.00 271.07 ? 498 ASP A O   1 
ATOM   2633  C  CB  . ASP A 1 499 ? 77.041  78.538  144.174 1.00 286.72 ? 498 ASP A CB  1 
ATOM   2634  C  CG  . ASP A 1 499 ? 77.613  77.302  143.490 1.00 306.98 ? 498 ASP A CG  1 
ATOM   2635  O  OD1 . ASP A 1 499 ? 76.986  76.786  142.549 1.00 244.54 ? 498 ASP A OD1 1 
ATOM   2636  O  OD2 . ASP A 1 499 ? 78.697  76.858  143.917 1.00 388.43 ? 498 ASP A OD2 1 
ATOM   2637  N  N   . ILE A 1 500 ? 75.413  81.509  143.966 1.00 258.86 ? 499 ILE A N   1 
ATOM   2638  C  CA  . ILE A 1 500 ? 74.827  82.727  144.515 1.00 253.22 ? 499 ILE A CA  1 
ATOM   2639  C  C   . ILE A 1 500 ? 74.367  83.549  143.306 1.00 276.86 ? 499 ILE A C   1 
ATOM   2640  O  O   . ILE A 1 500 ? 75.078  84.450  142.841 1.00 313.68 ? 499 ILE A O   1 
ATOM   2641  C  CB  . ILE A 1 500 ? 75.811  83.494  145.436 1.00 322.78 ? 499 ILE A CB  1 
ATOM   2642  C  CG1 . ILE A 1 500 ? 76.421  82.595  146.526 1.00 343.85 ? 499 ILE A CG1 1 
ATOM   2643  C  CG2 . ILE A 1 500 ? 75.138  84.737  146.025 1.00 345.33 ? 499 ILE A CG2 1 
ATOM   2644  C  CD1 . ILE A 1 500 ? 77.398  83.276  147.473 1.00 354.59 ? 499 ILE A CD1 1 
ATOM   2645  N  N   . PRO A 1 501 ? 73.171  83.254  142.742 1.00 316.99 ? 500 PRO A N   1 
ATOM   2646  C  CA  . PRO A 1 501 ? 72.775  83.820  141.451 1.00 335.01 ? 500 PRO A CA  1 
ATOM   2647  C  C   . PRO A 1 501 ? 72.454  85.312  141.595 1.00 326.01 ? 500 PRO A C   1 
ATOM   2648  O  O   . PRO A 1 501 ? 71.924  85.754  142.616 1.00 279.64 ? 500 PRO A O   1 
ATOM   2649  C  CB  . PRO A 1 501 ? 71.566  82.972  141.029 1.00 346.98 ? 500 PRO A CB  1 
ATOM   2650  C  CG  . PRO A 1 501 ? 70.978  82.480  142.340 1.00 372.89 ? 500 PRO A CG  1 
ATOM   2651  C  CD  . PRO A 1 501 ? 72.139  82.371  143.310 1.00 341.28 ? 500 PRO A CD  1 
ATOM   2652  N  N   . GLY A 1 502 ? 72.804  86.084  140.560 1.00 342.67 ? 501 GLY A N   1 
ATOM   2653  C  CA  . GLY A 1 502 ? 72.696  87.537  140.595 1.00 332.17 ? 501 GLY A CA  1 
ATOM   2654  C  C   . GLY A 1 502 ? 73.954  88.260  141.092 1.00 326.39 ? 501 GLY A C   1 
ATOM   2655  O  O   . GLY A 1 502 ? 74.020  89.482  140.945 1.00 275.25 ? 501 GLY A O   1 
ATOM   2656  N  N   . ALA A 1 503 ? 74.946  87.538  141.659 1.00 325.42 ? 502 ALA A N   1 
ATOM   2657  C  CA  . ALA A 1 503 ? 76.206  88.125  142.123 1.00 283.33 ? 502 ALA A CA  1 
ATOM   2658  C  C   . ALA A 1 503 ? 77.146  88.507  140.961 1.00 276.27 ? 502 ALA A C   1 
ATOM   2659  O  O   . ALA A 1 503 ? 77.914  89.467  141.067 1.00 243.10 ? 502 ALA A O   1 
ATOM   2660  C  CB  . ALA A 1 503 ? 76.877  87.171  143.092 1.00 247.74 ? 502 ALA A CB  1 
ATOM   2661  N  N   . VAL A 1 504 ? 77.090  87.757  139.848 1.00 261.33 ? 503 VAL A N   1 
ATOM   2662  C  CA  . VAL A 1 504 ? 77.869  88.027  138.646 1.00 207.23 ? 503 VAL A CA  1 
ATOM   2663  C  C   . VAL A 1 504 ? 77.322  89.254  137.920 1.00 212.82 ? 503 VAL A C   1 
ATOM   2664  O  O   . VAL A 1 504 ? 76.194  89.239  137.447 1.00 265.06 ? 503 VAL A O   1 
ATOM   2665  C  CB  . VAL A 1 504 ? 77.835  86.833  137.680 1.00 204.67 ? 503 VAL A CB  1 
ATOM   2666  C  CG1 . VAL A 1 504 ? 78.574  87.162  136.375 1.00 197.56 ? 503 VAL A CG1 1 
ATOM   2667  C  CG2 . VAL A 1 504 ? 78.374  85.576  138.354 1.00 238.99 ? 503 VAL A CG2 1 
ATOM   2668  N  N   . SER A 1 505 ? 78.126  90.312  137.821 1.00 198.37 ? 504 SER A N   1 
ATOM   2669  C  CA  . SER A 1 505 ? 77.852  91.431  136.932 1.00 194.59 ? 504 SER A CA  1 
ATOM   2670  C  C   . SER A 1 505 ? 78.330  91.112  135.509 1.00 115.46 ? 504 SER A C   1 
ATOM   2671  O  O   . SER A 1 505 ? 79.297  90.384  135.338 1.00 165.94 ? 504 SER A O   1 
ATOM   2672  C  CB  . SER A 1 505 ? 78.494  92.683  137.511 1.00 211.61 ? 504 SER A CB  1 
ATOM   2673  O  OG  . SER A 1 505 ? 78.312  93.809  136.660 1.00 214.05 ? 504 SER A OG  1 
ATOM   2674  N  N   . ALA A 1 506 ? 77.686  91.690  134.492 1.00 151.06 ? 505 ALA A N   1 
ATOM   2675  C  CA  . ALA A 1 506 ? 78.002  91.428  133.084 1.00 216.50 ? 505 ALA A CA  1 
ATOM   2676  C  C   . ALA A 1 506 ? 79.474  91.669  132.751 1.00 220.01 ? 505 ALA A C   1 
ATOM   2677  O  O   . ALA A 1 506 ? 80.151  90.777  132.234 1.00 251.37 ? 505 ALA A O   1 
ATOM   2678  C  CB  . ALA A 1 506 ? 77.117  92.273  132.196 1.00 284.98 ? 505 ALA A CB  1 
ATOM   2679  N  N   . ASN A 1 507 ? 79.944  92.878  133.077 1.00 203.03 ? 506 ASN A N   1 
ATOM   2680  C  CA  . ASN A 1 507 ? 81.325  93.330  132.915 1.00 197.58 ? 506 ASN A CA  1 
ATOM   2681  C  C   . ASN A 1 507 ? 82.385  92.411  133.578 1.00 179.24 ? 506 ASN A C   1 
ATOM   2682  O  O   . ASN A 1 507 ? 83.544  92.485  133.159 1.00 259.05 ? 506 ASN A O   1 
ATOM   2683  C  CB  . ASN A 1 507 ? 81.448  94.787  133.403 1.00 222.63 ? 506 ASN A CB  1 
ATOM   2684  C  CG  . ASN A 1 507 ? 81.131  94.952  134.881 1.00 259.93 ? 506 ASN A CG  1 
ATOM   2685  O  OD1 . ASN A 1 507 ? 80.749  93.980  135.540 1.00 263.30 ? 506 ASN A OD1 1 
ATOM   2686  N  ND2 . ASN A 1 507 ? 81.280  96.155  135.433 1.00 263.36 ? 506 ASN A ND2 1 
ATOM   2687  N  N   . MET A 1 508 ? 82.052  91.553  134.564 1.00 144.52 ? 507 MET A N   1 
ATOM   2688  C  CA  . MET A 1 508 ? 82.990  90.568  135.124 1.00 131.52 ? 507 MET A CA  1 
ATOM   2689  C  C   . MET A 1 508 ? 83.207  89.312  134.260 1.00 142.50 ? 507 MET A C   1 
ATOM   2690  O  O   . MET A 1 508 ? 84.014  88.487  134.653 1.00 197.26 ? 507 MET A O   1 
ATOM   2691  C  CB  . MET A 1 508 ? 82.507  90.038  136.476 1.00 143.94 ? 507 MET A CB  1 
ATOM   2692  C  CG  . MET A 1 508 ? 82.267  91.131  137.512 1.00 241.14 ? 507 MET A CG  1 
ATOM   2693  S  SD  . MET A 1 508 ? 81.561  90.463  139.068 1.00 279.67 ? 507 MET A SD  1 
ATOM   2694  C  CE  . MET A 1 508 ? 82.997  89.578  139.671 1.00 291.79 ? 507 MET A CE  1 
ATOM   2695  N  N   . THR A 1 509 ? 82.546  89.148  133.104 1.00 147.15 ? 508 THR A N   1 
ATOM   2696  C  CA  . THR A 1 509 ? 82.507  87.886  132.384 1.00 112.69 ? 508 THR A CA  1 
ATOM   2697  C  C   . THR A 1 509 ? 83.104  88.008  130.981 1.00 109.37 ? 508 THR A C   1 
ATOM   2698  O  O   . THR A 1 509 ? 83.111  89.082  130.379 1.00 114.79 ? 508 THR A O   1 
ATOM   2699  C  CB  . THR A 1 509 ? 81.071  87.399  132.197 1.00 173.34 ? 508 THR A CB  1 
ATOM   2700  O  OG1 . THR A 1 509 ? 80.364  88.211  131.239 1.00 166.44 ? 508 THR A OG1 1 
ATOM   2701  C  CG2 . THR A 1 509 ? 80.310  87.376  133.508 1.00 187.25 ? 508 THR A CG2 1 
ATOM   2702  N  N   . VAL A 1 510 ? 83.590  86.880  130.436 1.00 95.16  ? 509 VAL A N   1 
ATOM   2703  C  CA  . VAL A 1 510 ? 84.223  86.870  129.118 1.00 126.11 ? 509 VAL A CA  1 
ATOM   2704  C  C   . VAL A 1 510 ? 83.282  87.436  128.063 1.00 127.50 ? 509 VAL A C   1 
ATOM   2705  O  O   . VAL A 1 510 ? 83.688  88.259  127.249 1.00 87.50  ? 509 VAL A O   1 
ATOM   2706  C  CB  . VAL A 1 510 ? 84.686  85.464  128.699 1.00 130.88 ? 509 VAL A CB  1 
ATOM   2707  C  CG1 . VAL A 1 510 ? 85.161  85.469  127.231 1.00 111.95 ? 509 VAL A CG1 1 
ATOM   2708  C  CG2 . VAL A 1 510 ? 85.751  84.869  129.645 1.00 121.64 ? 509 VAL A CG2 1 
ATOM   2709  N  N   . LYS A 1 511 ? 82.027  86.975  128.101 1.00 178.84 ? 510 LYS A N   1 
ATOM   2710  C  CA  . LYS A 1 511 ? 80.999  87.391  127.166 1.00 219.87 ? 510 LYS A CA  1 
ATOM   2711  C  C   . LYS A 1 511 ? 80.775  88.899  127.268 1.00 194.47 ? 510 LYS A C   1 
ATOM   2712  O  O   . LYS A 1 511 ? 80.616  89.568  126.221 1.00 125.74 ? 510 LYS A O   1 
ATOM   2713  C  CB  . LYS A 1 511 ? 79.721  86.591  127.444 1.00 272.89 ? 510 LYS A CB  1 
ATOM   2714  C  CG  . LYS A 1 511 ? 78.647  86.734  126.382 1.00 344.45 ? 510 LYS A CG  1 
ATOM   2715  C  CD  . LYS A 1 511 ? 77.459  85.833  126.621 1.00 379.49 ? 510 LYS A CD  1 
ATOM   2716  C  CE  . LYS A 1 511 ? 76.464  85.831  125.479 1.00 416.98 ? 510 LYS A CE  1 
ATOM   2717  N  NZ  . LYS A 1 511 ? 76.999  85.178  124.257 1.00 421.31 ? 510 LYS A NZ  1 
ATOM   2718  N  N   . GLY A 1 512 ? 80.770  89.412  128.522 1.00 150.70 ? 511 GLY A N   1 
ATOM   2719  C  CA  . GLY A 1 512 ? 80.512  90.817  128.804 1.00 214.86 ? 511 GLY A CA  1 
ATOM   2720  C  C   . GLY A 1 512 ? 81.665  91.757  128.467 1.00 187.88 ? 511 GLY A C   1 
ATOM   2721  O  O   . GLY A 1 512 ? 81.450  92.955  128.283 1.00 164.16 ? 511 GLY A O   1 
ATOM   2722  N  N   . GLN A 1 513 ? 82.887  91.217  128.408 1.00 184.95 ? 512 GLN A N   1 
ATOM   2723  C  CA  . GLN A 1 513 ? 84.051  91.976  127.985 1.00 165.79 ? 512 GLN A CA  1 
ATOM   2724  C  C   . GLN A 1 513 ? 84.280  91.861  126.479 1.00 147.22 ? 512 GLN A C   1 
ATOM   2725  O  O   . GLN A 1 513 ? 84.745  92.831  125.887 1.00 179.71 ? 512 GLN A O   1 
ATOM   2726  C  CB  . GLN A 1 513 ? 85.286  91.540  128.786 1.00 116.62 ? 512 GLN A CB  1 
ATOM   2727  C  CG  . GLN A 1 513 ? 85.129  91.910  130.240 1.00 152.80 ? 512 GLN A CG  1 
ATOM   2728  C  CD  . GLN A 1 513 ? 86.350  91.748  131.071 1.00 141.43 ? 512 GLN A CD  1 
ATOM   2729  O  OE1 . GLN A 1 513 ? 87.462  91.738  130.557 1.00 168.98 ? 512 GLN A OE1 1 
ATOM   2730  N  NE2 . GLN A 1 513 ? 86.112  91.681  132.368 1.00 165.21 ? 512 GLN A NE2 1 
ATOM   2731  N  N   . SER A 1 514 ? 83.997  90.703  125.871 1.00 117.08 ? 513 SER A N   1 
ATOM   2732  C  CA  . SER A 1 514 ? 84.360  90.434  124.488 1.00 169.02 ? 513 SER A CA  1 
ATOM   2733  C  C   . SER A 1 514 ? 83.831  91.481  123.509 1.00 201.54 ? 513 SER A C   1 
ATOM   2734  O  O   . SER A 1 514 ? 84.446  91.670  122.440 1.00 190.51 ? 513 SER A O   1 
ATOM   2735  C  CB  . SER A 1 514 ? 83.916  89.049  124.070 1.00 220.74 ? 513 SER A CB  1 
ATOM   2736  O  OG  . SER A 1 514 ? 84.605  88.030  124.791 1.00 203.33 ? 513 SER A OG  1 
ATOM   2737  N  N   . GLU A 1 515 ? 82.700  92.109  123.887 1.00 199.77 ? 514 GLU A N   1 
ATOM   2738  C  CA  . GLU A 1 515 ? 82.004  93.090  123.064 1.00 276.19 ? 514 GLU A CA  1 
ATOM   2739  C  C   . GLU A 1 515 ? 82.607  94.501  123.152 1.00 248.50 ? 514 GLU A C   1 
ATOM   2740  O  O   . GLU A 1 515 ? 82.390  95.298  122.245 1.00 243.66 ? 514 GLU A O   1 
ATOM   2741  C  CB  . GLU A 1 515 ? 80.520  93.092  123.460 1.00 311.49 ? 514 GLU A CB  1 
ATOM   2742  C  CG  . GLU A 1 515 ? 80.205  93.585  124.877 1.00 287.92 ? 514 GLU A CG  1 
ATOM   2743  C  CD  . GLU A 1 515 ? 78.721  93.655  125.228 1.00 311.31 ? 514 GLU A CD  1 
ATOM   2744  O  OE1 . GLU A 1 515 ? 78.018  92.639  125.028 1.00 308.86 ? 514 GLU A OE1 1 
ATOM   2745  O  OE2 . GLU A 1 515 ? 78.263  94.725  125.714 1.00 264.88 ? 514 GLU A OE2 1 
ATOM   2746  N  N   . ASP A 1 516 ? 83.351  94.819  124.227 1.00 201.83 ? 515 ASP A N   1 
ATOM   2747  C  CA  . ASP A 1 516 ? 83.604  96.184  124.679 1.00 163.08 ? 515 ASP A CA  1 
ATOM   2748  C  C   . ASP A 1 516 ? 85.067  96.553  124.432 1.00 177.96 ? 515 ASP A C   1 
ATOM   2749  O  O   . ASP A 1 516 ? 85.954  95.980  125.076 1.00 305.02 ? 515 ASP A O   1 
ATOM   2750  C  CB  . ASP A 1 516 ? 83.234  96.283  126.161 1.00 218.04 ? 515 ASP A CB  1 
ATOM   2751  C  CG  . ASP A 1 516 ? 83.591  97.590  126.862 1.00 240.58 ? 515 ASP A CG  1 
ATOM   2752  O  OD1 . ASP A 1 516 ? 84.188  98.470  126.187 1.00 187.46 ? 515 ASP A OD1 1 
ATOM   2753  O  OD2 . ASP A 1 516 ? 83.272  97.722  128.084 1.00 214.72 ? 515 ASP A OD2 1 
ATOM   2754  N  N   . PRO A 1 517 ? 85.390  97.493  123.505 1.00 183.96 ? 516 PRO A N   1 
ATOM   2755  C  CA  . PRO A 1 517 ? 86.775  97.926  123.262 1.00 221.71 ? 516 PRO A CA  1 
ATOM   2756  C  C   . PRO A 1 517 ? 87.542  98.471  124.465 1.00 172.37 ? 516 PRO A C   1 
ATOM   2757  O  O   . PRO A 1 517 ? 88.766  98.367  124.470 1.00 185.39 ? 516 PRO A O   1 
ATOM   2758  C  CB  . PRO A 1 517 ? 86.634  99.035  122.201 1.00 216.26 ? 516 PRO A CB  1 
ATOM   2759  C  CG  . PRO A 1 517 ? 85.391  98.625  121.469 1.00 257.30 ? 516 PRO A CG  1 
ATOM   2760  C  CD  . PRO A 1 517 ? 84.469  98.165  122.585 1.00 233.16 ? 516 PRO A CD  1 
ATOM   2761  N  N   . GLY A 1 518 ? 86.822  99.018  125.452 1.00 142.80 ? 517 GLY A N   1 
ATOM   2762  C  CA  . GLY A 1 518 ? 87.427  99.484  126.692 1.00 168.48 ? 517 GLY A CA  1 
ATOM   2763  C  C   . GLY A 1 518 ? 87.795  98.385  127.693 1.00 140.39 ? 517 GLY A C   1 
ATOM   2764  O  O   . GLY A 1 518 ? 88.551  98.660  128.613 1.00 149.17 ? 517 GLY A O   1 
ATOM   2765  N  N   . SER A 1 519 ? 87.275  97.160  127.535 1.00 167.29 ? 518 SER A N   1 
ATOM   2766  C  CA  . SER A 1 519 ? 87.404  96.107  128.539 1.00 169.18 ? 518 SER A CA  1 
ATOM   2767  C  C   . SER A 1 519 ? 88.821  95.590  128.658 1.00 110.38 ? 518 SER A C   1 
ATOM   2768  O  O   . SER A 1 519 ? 89.614  95.702  127.736 1.00 110.21 ? 518 SER A O   1 
ATOM   2769  C  CB  . SER A 1 519 ? 86.554  94.915  128.219 1.00 207.75 ? 518 SER A CB  1 
ATOM   2770  O  OG  . SER A 1 519 ? 87.035  94.302  127.028 1.00 148.22 ? 518 SER A OG  1 
ATOM   2771  N  N   . LEU A 1 520 ? 89.091  94.977  129.813 1.00 119.69 ? 519 LEU A N   1 
ATOM   2772  C  CA  . LEU A 1 520 ? 90.391  94.378  130.095 1.00 129.90 ? 519 LEU A CA  1 
ATOM   2773  C  C   . LEU A 1 520 ? 90.771  93.325  129.037 1.00 95.87  ? 519 LEU A C   1 
ATOM   2774  O  O   . LEU A 1 520 ? 91.853  93.352  128.473 1.00 73.66  ? 519 LEU A O   1 
ATOM   2775  C  CB  . LEU A 1 520 ? 90.329  93.832  131.527 1.00 112.90 ? 519 LEU A CB  1 
ATOM   2776  C  CG  . LEU A 1 520 ? 91.605  93.248  132.103 1.00 106.14 ? 519 LEU A CG  1 
ATOM   2777  C  CD1 . LEU A 1 520 ? 92.819  94.091  131.791 1.00 127.51 ? 519 LEU A CD1 1 
ATOM   2778  C  CD2 . LEU A 1 520 ? 91.444  93.131  133.593 1.00 136.13 ? 519 LEU A CD2 1 
ATOM   2779  N  N   . LEU A 1 521 ? 89.870  92.411  128.737 1.00 101.64 ? 520 LEU A N   1 
ATOM   2780  C  CA  . LEU A 1 521 ? 90.103  91.404  127.721 1.00 100.62 ? 520 LEU A CA  1 
ATOM   2781  C  C   . LEU A 1 521 ? 90.303  92.009  126.319 1.00 82.87  ? 520 LEU A C   1 
ATOM   2782  O  O   . LEU A 1 521 ? 91.049  91.427  125.546 1.00 76.02  ? 520 LEU A O   1 
ATOM   2783  C  CB  . LEU A 1 521 ? 88.901  90.466  127.799 1.00 117.32 ? 520 LEU A CB  1 
ATOM   2784  C  CG  . LEU A 1 521 ? 88.823  89.351  126.777 1.00 95.01  ? 520 LEU A CG  1 
ATOM   2785  C  CD1 . LEU A 1 521 ? 89.875  88.390  127.051 1.00 119.13 ? 520 LEU A CD1 1 
ATOM   2786  C  CD2 . LEU A 1 521 ? 87.505  88.640  126.897 1.00 147.95 ? 520 LEU A CD2 1 
ATOM   2787  N  N   . SER A 1 522 ? 89.694  93.160  125.999 1.00 73.73  ? 521 SER A N   1 
ATOM   2788  C  CA  . SER A 1 522 ? 90.032  93.835  124.755 1.00 135.22 ? 521 SER A CA  1 
ATOM   2789  C  C   . SER A 1 522 ? 91.458  94.435  124.710 1.00 162.09 ? 521 SER A C   1 
ATOM   2790  O  O   . SER A 1 522 ? 92.033  94.636  123.631 1.00 127.89 ? 521 SER A O   1 
ATOM   2791  C  CB  . SER A 1 522 ? 88.997  94.880  124.459 1.00 177.12 ? 521 SER A CB  1 
ATOM   2792  O  OG  . SER A 1 522 ? 87.769  94.232  124.161 1.00 189.38 ? 521 SER A OG  1 
ATOM   2793  N  N   . LEU A 1 523 ? 92.027  94.735  125.881 1.00 142.65 ? 522 LEU A N   1 
ATOM   2794  C  CA  . LEU A 1 523 ? 93.416  95.141  125.991 1.00 112.34 ? 522 LEU A CA  1 
ATOM   2795  C  C   . LEU A 1 523 ? 94.318  93.911  125.905 1.00 110.88 ? 522 LEU A C   1 
ATOM   2796  O  O   . LEU A 1 523 ? 95.352  93.956  125.253 1.00 147.47 ? 522 LEU A O   1 
ATOM   2797  C  CB  . LEU A 1 523 ? 93.606  95.899  127.312 1.00 108.91 ? 522 LEU A CB  1 
ATOM   2798  C  CG  . LEU A 1 523 ? 95.044  96.260  127.673 1.00 138.93 ? 522 LEU A CG  1 
ATOM   2799  C  CD1 . LEU A 1 523 ? 95.609  97.240  126.626 1.00 132.27 ? 522 LEU A CD1 1 
ATOM   2800  C  CD2 . LEU A 1 523 ? 95.158  96.793  129.109 1.00 146.62 ? 522 LEU A CD2 1 
ATOM   2801  N  N   . PHE A 1 524 ? 93.981  92.805  126.564 1.00 84.86  ? 523 PHE A N   1 
ATOM   2802  C  CA  . PHE A 1 524 ? 94.828  91.620  126.520 1.00 74.24  ? 523 PHE A CA  1 
ATOM   2803  C  C   . PHE A 1 524 ? 94.907  91.126  125.095 1.00 90.37  ? 523 PHE A C   1 
ATOM   2804  O  O   . PHE A 1 524 ? 96.015  90.840  124.644 1.00 110.28 ? 523 PHE A O   1 
ATOM   2805  C  CB  . PHE A 1 524 ? 94.258  90.502  127.413 1.00 74.59  ? 523 PHE A CB  1 
ATOM   2806  C  CG  . PHE A 1 524 ? 95.082  89.264  127.618 1.00 58.16  ? 523 PHE A CG  1 
ATOM   2807  C  CD1 . PHE A 1 524 ? 95.336  88.410  126.601 1.00 54.24  ? 523 PHE A CD1 1 
ATOM   2808  C  CD2 . PHE A 1 524 ? 95.665  88.981  128.850 1.00 85.00  ? 523 PHE A CD2 1 
ATOM   2809  C  CE1 . PHE A 1 524 ? 96.116  87.285  126.843 1.00 99.72  ? 523 PHE A CE1 1 
ATOM   2810  C  CE2 . PHE A 1 524 ? 96.474  87.860  129.078 1.00 83.63  ? 523 PHE A CE2 1 
ATOM   2811  C  CZ  . PHE A 1 524 ? 96.683  86.980  128.076 1.00 76.03  ? 523 PHE A CZ  1 
ATOM   2812  N  N   . ARG A 1 525 ? 93.742  90.989  124.432 1.00 103.76 ? 524 ARG A N   1 
ATOM   2813  C  CA  . ARG A 1 525 ? 93.710  90.455  123.082 1.00 132.37 ? 524 ARG A CA  1 
ATOM   2814  C  C   . ARG A 1 525 ? 94.614  91.322  122.215 1.00 135.52 ? 524 ARG A C   1 
ATOM   2815  O  O   . ARG A 1 525 ? 95.346  90.803  121.372 1.00 144.12 ? 524 ARG A O   1 
ATOM   2816  C  CB  . ARG A 1 525 ? 92.283  90.415  122.527 1.00 180.38 ? 524 ARG A CB  1 
ATOM   2817  C  CG  . ARG A 1 525 ? 91.437  89.266  123.053 1.00 180.88 ? 524 ARG A CG  1 
ATOM   2818  C  CD  . ARG A 1 525 ? 89.958  89.329  122.669 1.00 133.65 ? 524 ARG A CD  1 
ATOM   2819  N  NE  . ARG A 1 525 ? 89.303  88.128  123.146 1.00 126.76 ? 524 ARG A NE  1 
ATOM   2820  C  CZ  . ARG A 1 525 ? 88.013  87.903  123.028 1.00 208.46 ? 524 ARG A CZ  1 
ATOM   2821  N  NH1 . ARG A 1 525 ? 87.463  86.810  123.531 1.00 187.65 ? 524 ARG A NH1 1 
ATOM   2822  N  NH2 . ARG A 1 525 ? 87.268  88.800  122.402 1.00 290.26 ? 524 ARG A NH2 1 
ATOM   2823  N  N   . ARG A 1 526 ? 94.541  92.649  122.418 1.00 98.96  ? 525 ARG A N   1 
ATOM   2824  C  CA  . ARG A 1 526 ? 95.193  93.572  121.509 1.00 117.85 ? 525 ARG A CA  1 
ATOM   2825  C  C   . ARG A 1 526 ? 96.701  93.481  121.666 1.00 101.39 ? 525 ARG A C   1 
ATOM   2826  O  O   . ARG A 1 526 ? 97.425  93.482  120.670 1.00 97.63  ? 525 ARG A O   1 
ATOM   2827  C  CB  . ARG A 1 526 ? 94.672  94.986  121.702 1.00 97.71  ? 525 ARG A CB  1 
ATOM   2828  C  CG  . ARG A 1 526 ? 95.072  95.831  120.489 1.00 153.64 ? 525 ARG A CG  1 
ATOM   2829  C  CD  . ARG A 1 526 ? 94.695  97.285  120.556 1.00 189.11 ? 525 ARG A CD  1 
ATOM   2830  N  NE  . ARG A 1 526 ? 93.410  97.569  121.201 1.00 129.89 ? 525 ARG A NE  1 
ATOM   2831  C  CZ  . ARG A 1 526 ? 93.098  98.768  121.640 1.00 174.56 ? 525 ARG A CZ  1 
ATOM   2832  N  NH1 . ARG A 1 526 ? 92.165  98.894  122.561 1.00 178.73 ? 525 ARG A NH1 1 
ATOM   2833  N  NH2 . ARG A 1 526 ? 93.775  99.813  121.168 1.00 229.44 ? 525 ARG A NH2 1 
ATOM   2834  N  N   . LEU A 1 527 ? 97.147  93.409  122.915 1.00 108.25 ? 526 LEU A N   1 
ATOM   2835  C  CA  . LEU A 1 527 ? 98.577  93.347  123.228 1.00 103.27 ? 526 LEU A CA  1 
ATOM   2836  C  C   . LEU A 1 527 ? 99.172  92.033  122.781 1.00 94.65  ? 526 LEU A C   1 
ATOM   2837  O  O   . LEU A 1 527 ? 100.310 92.017  122.313 1.00 77.87  ? 526 LEU A O   1 
ATOM   2838  C  CB  . LEU A 1 527 ? 98.776  93.531  124.727 1.00 82.39  ? 526 LEU A CB  1 
ATOM   2839  C  CG  . LEU A 1 527 ? 98.700  95.000  125.088 1.00 83.94  ? 526 LEU A CG  1 
ATOM   2840  C  CD1 . LEU A 1 527 ? 98.532  95.143  126.584 1.00 87.99  ? 526 LEU A CD1 1 
ATOM   2841  C  CD2 . LEU A 1 527 ? 99.930  95.708  124.507 1.00 97.10  ? 526 LEU A CD2 1 
ATOM   2842  N  N   . SER A 1 528 ? 98.388  90.967  122.931 1.00 105.27 ? 527 SER A N   1 
ATOM   2843  C  CA  . SER A 1 528 ? 98.878  89.656  122.586 1.00 103.80 ? 527 SER A CA  1 
ATOM   2844  C  C   . SER A 1 528 ? 99.239  89.658  121.096 1.00 94.89  ? 527 SER A C   1 
ATOM   2845  O  O   . SER A 1 528 ? 100.163 88.951  120.697 1.00 84.36  ? 527 SER A O   1 
ATOM   2846  C  CB  . SER A 1 528 ? 97.868  88.599  123.049 1.00 78.44  ? 527 SER A CB  1 
ATOM   2847  O  OG  . SER A 1 528 ? 98.434  87.307  122.923 1.00 93.78  ? 527 SER A OG  1 
ATOM   2848  N  N   . ASP A 1 529 ? 98.476  90.420  120.292 1.00 86.56  ? 528 ASP A N   1 
ATOM   2849  C  CA  . ASP A 1 529 ? 98.705  90.547  118.871 1.00 107.95 ? 528 ASP A CA  1 
ATOM   2850  C  C   . ASP A 1 529 ? 100.083 91.129  118.678 1.00 100.73 ? 528 ASP A C   1 
ATOM   2851  O  O   . ASP A 1 529 ? 100.917 90.559  117.947 1.00 156.82 ? 528 ASP A O   1 
ATOM   2852  C  CB  . ASP A 1 529 ? 97.625  91.381  118.171 1.00 160.19 ? 528 ASP A CB  1 
ATOM   2853  C  CG  . ASP A 1 529 ? 97.644  91.286  116.649 1.00 259.87 ? 528 ASP A CG  1 
ATOM   2854  O  OD1 . ASP A 1 529 ? 97.811  90.144  116.128 1.00 298.48 ? 528 ASP A OD1 1 
ATOM   2855  O  OD2 . ASP A 1 529 ? 97.492  92.352  115.990 1.00 258.18 ? 528 ASP A OD2 1 
ATOM   2856  N  N   . GLN A 1 530 ? 100.322 92.282  119.308 1.00 89.21  ? 529 GLN A N   1 
ATOM   2857  C  CA  . GLN A 1 530 ? 101.552 93.035  119.057 1.00 94.57  ? 529 GLN A CA  1 
ATOM   2858  C  C   . GLN A 1 530 ? 102.775 92.201  119.408 1.00 87.17  ? 529 GLN A C   1 
ATOM   2859  O  O   . GLN A 1 530 ? 103.670 92.113  118.610 1.00 101.14 ? 529 GLN A O   1 
ATOM   2860  C  CB  . GLN A 1 530 ? 101.484 94.314  119.861 1.00 139.58 ? 529 GLN A CB  1 
ATOM   2861  C  CG  . GLN A 1 530 ? 100.266 95.162  119.482 1.00 127.06 ? 529 GLN A CG  1 
ATOM   2862  C  CD  . GLN A 1 530 ? 100.519 95.643  118.092 1.00 153.78 ? 529 GLN A CD  1 
ATOM   2863  O  OE1 . GLN A 1 530 ? 101.680 95.640  117.664 1.00 71.91  ? 529 GLN A OE1 1 
ATOM   2864  N  NE2 . GLN A 1 530 ? 99.454  96.080  117.424 1.00 229.91 ? 529 GLN A NE2 1 
ATOM   2865  N  N   . ARG A 1 531 ? 102.777 91.567  120.572 1.00 78.13  ? 530 ARG A N   1 
ATOM   2866  C  CA  . ARG A 1 531 ? 103.889 90.783  121.045 1.00 66.85  ? 530 ARG A CA  1 
ATOM   2867  C  C   . ARG A 1 531 ? 104.090 89.560  120.200 1.00 91.07  ? 530 ARG A C   1 
ATOM   2868  O  O   . ARG A 1 531 ? 105.132 88.940  120.402 1.00 155.84 ? 530 ARG A O   1 
ATOM   2869  C  CB  . ARG A 1 531 ? 103.538 90.240  122.435 1.00 96.05  ? 530 ARG A CB  1 
ATOM   2870  C  CG  . ARG A 1 531 ? 104.482 89.248  123.103 1.00 66.03  ? 530 ARG A CG  1 
ATOM   2871  C  CD  . ARG A 1 531 ? 105.852 89.897  123.047 1.00 58.62  ? 530 ARG A CD  1 
ATOM   2872  N  NE  . ARG A 1 531 ? 106.665 89.080  123.895 1.00 79.82  ? 530 ARG A NE  1 
ATOM   2873  C  CZ  . ARG A 1 531 ? 107.168 87.943  123.500 1.00 78.52  ? 530 ARG A CZ  1 
ATOM   2874  N  NH1 . ARG A 1 531 ? 107.980 87.240  124.258 1.00 98.57  ? 530 ARG A NH1 1 
ATOM   2875  N  NH2 . ARG A 1 531 ? 106.893 87.540  122.302 1.00 95.57  ? 530 ARG A NH2 1 
ATOM   2876  N  N   . SER A 1 532 ? 103.131 89.162  119.325 1.00 82.02  ? 531 SER A N   1 
ATOM   2877  C  CA  . SER A 1 532 ? 103.311 87.915  118.596 1.00 148.02 ? 531 SER A CA  1 
ATOM   2878  C  C   . SER A 1 532 ? 103.584 88.148  117.101 1.00 142.22 ? 531 SER A C   1 
ATOM   2879  O  O   . SER A 1 532 ? 103.905 87.190  116.388 1.00 192.17 ? 531 SER A O   1 
ATOM   2880  C  CB  . SER A 1 532 ? 102.145 86.990  118.889 1.00 126.49 ? 531 SER A CB  1 
ATOM   2881  O  OG  . SER A 1 532 ? 100.973 87.573  118.388 1.00 125.62 ? 531 SER A OG  1 
ATOM   2882  N  N   . LYS A 1 533 ? 103.481 89.391  116.642 1.00 112.87 ? 532 LYS A N   1 
ATOM   2883  C  CA  . LYS A 1 533 ? 103.686 89.692  115.239 1.00 155.71 ? 532 LYS A CA  1 
ATOM   2884  C  C   . LYS A 1 533 ? 104.915 90.577  115.046 1.00 127.17 ? 532 LYS A C   1 
ATOM   2885  O  O   . LYS A 1 533 ? 105.563 90.419  114.017 1.00 174.55 ? 532 LYS A O   1 
ATOM   2886  C  CB  . LYS A 1 533 ? 102.403 90.321  114.647 1.00 178.84 ? 532 LYS A CB  1 
ATOM   2887  C  CG  . LYS A 1 533 ? 102.202 91.797  114.933 1.00 169.22 ? 532 LYS A CG  1 
ATOM   2888  C  CD  . LYS A 1 533 ? 100.778 92.292  114.945 1.00 181.14 ? 532 LYS A CD  1 
ATOM   2889  C  CE  . LYS A 1 533 ? 100.126 92.406  113.596 1.00 248.11 ? 532 LYS A CE  1 
ATOM   2890  N  NZ  . LYS A 1 533 ? 98.837  93.144  113.696 1.00 278.61 ? 532 LYS A NZ  1 
ATOM   2891  N  N   . GLU A 1 534 ? 105.198 91.501  115.982 1.00 112.54 ? 533 GLU A N   1 
ATOM   2892  C  CA  . GLU A 1 534 ? 106.114 92.616  115.758 1.00 114.06 ? 533 GLU A CA  1 
ATOM   2893  C  C   . GLU A 1 534 ? 107.524 92.193  116.143 1.00 125.60 ? 533 GLU A C   1 
ATOM   2894  O  O   . GLU A 1 534 ? 107.801 91.782  117.277 1.00 154.16 ? 533 GLU A O   1 
ATOM   2895  C  CB  . GLU A 1 534 ? 105.684 93.828  116.571 1.00 89.88  ? 533 GLU A CB  1 
ATOM   2896  C  CG  . GLU A 1 534 ? 104.637 94.616  115.916 1.00 158.62 ? 533 GLU A CG  1 
ATOM   2897  C  CD  . GLU A 1 534 ? 105.129 95.448  114.737 1.00 269.17 ? 533 GLU A CD  1 
ATOM   2898  O  OE1 . GLU A 1 534 ? 106.389 95.394  114.388 1.00 187.26 ? 533 GLU A OE1 1 
ATOM   2899  O  OE2 . GLU A 1 534 ? 104.257 96.164  114.156 1.00 290.36 ? 533 GLU A OE2 1 
ATOM   2900  N  N   . ARG A 1 535 ? 108.440 92.317  115.190 1.00 130.07 ? 534 ARG A N   1 
ATOM   2901  C  CA  . ARG A 1 535 ? 109.730 91.694  115.391 1.00 129.27 ? 534 ARG A CA  1 
ATOM   2902  C  C   . ARG A 1 535 ? 110.415 92.362  116.569 1.00 103.25 ? 534 ARG A C   1 
ATOM   2903  O  O   . ARG A 1 535 ? 111.204 91.749  117.250 1.00 102.59 ? 534 ARG A O   1 
ATOM   2904  C  CB  . ARG A 1 535 ? 110.543 91.729  114.101 1.00 171.77 ? 534 ARG A CB  1 
ATOM   2905  C  CG  . ARG A 1 535 ? 111.664 90.718  114.164 1.00 180.88 ? 534 ARG A CG  1 
ATOM   2906  C  CD  . ARG A 1 535 ? 112.364 90.467  112.840 1.00 198.24 ? 534 ARG A CD  1 
ATOM   2907  N  NE  . ARG A 1 535 ? 111.512 89.858  111.836 1.00 151.60 ? 534 ARG A NE  1 
ATOM   2908  C  CZ  . ARG A 1 535 ? 111.272 90.396  110.653 1.00 177.34 ? 534 ARG A CZ  1 
ATOM   2909  N  NH1 . ARG A 1 535 ? 110.444 89.801  109.807 1.00 246.80 ? 534 ARG A NH1 1 
ATOM   2910  N  NH2 . ARG A 1 535 ? 111.860 91.528  110.299 1.00 193.22 ? 534 ARG A NH2 1 
ATOM   2911  N  N   . SER A 1 536 ? 110.086 93.634  116.801 1.00 119.23 ? 535 SER A N   1 
ATOM   2912  C  CA  . SER A 1 536 ? 110.720 94.435  117.850 1.00 109.29 ? 535 SER A CA  1 
ATOM   2913  C  C   . SER A 1 536 ? 110.354 93.930  119.230 1.00 92.09  ? 535 SER A C   1 
ATOM   2914  O  O   . SER A 1 536 ? 111.244 93.787  120.027 1.00 78.19  ? 535 SER A O   1 
ATOM   2915  C  CB  . SER A 1 536 ? 110.300 95.844  117.696 1.00 113.76 ? 535 SER A CB  1 
ATOM   2916  O  OG  . SER A 1 536 ? 111.265 96.715  118.144 1.00 61.33  ? 535 SER A OG  1 
ATOM   2917  N  N   . LEU A 1 537 ? 109.076 93.649  119.512 1.00 74.65  ? 536 LEU A N   1 
ATOM   2918  C  CA  . LEU A 1 537 ? 108.657 93.053  120.803 1.00 70.79  ? 536 LEU A CA  1 
ATOM   2919  C  C   . LEU A 1 537 ? 108.979 91.568  120.843 1.00 69.12  ? 536 LEU A C   1 
ATOM   2920  O  O   . LEU A 1 537 ? 109.263 91.085  121.915 1.00 79.77  ? 536 LEU A O   1 
ATOM   2921  C  CB  . LEU A 1 537 ? 107.173 93.257  121.158 1.00 54.67  ? 536 LEU A CB  1 
ATOM   2922  C  CG  . LEU A 1 537 ? 106.708 94.705  120.920 1.00 70.97  ? 536 LEU A CG  1 
ATOM   2923  C  CD1 . LEU A 1 537 ? 105.236 94.895  121.190 1.00 74.46  ? 536 LEU A CD1 1 
ATOM   2924  C  CD2 . LEU A 1 537 ? 107.529 95.651  121.770 1.00 72.11  ? 536 LEU A CD2 1 
ATOM   2925  N  N   . LEU A 1 538 ? 108.987 90.868  119.710 1.00 80.55  ? 537 LEU A N   1 
ATOM   2926  C  CA  . LEU A 1 538 ? 109.256 89.432  119.662 1.00 96.21  ? 537 LEU A CA  1 
ATOM   2927  C  C   . LEU A 1 538 ? 110.642 89.123  120.151 1.00 81.97  ? 537 LEU A C   1 
ATOM   2928  O  O   . LEU A 1 538 ? 110.727 88.106  120.834 1.00 134.55 ? 537 LEU A O   1 
ATOM   2929  C  CB  . LEU A 1 538 ? 109.120 88.872  118.249 1.00 122.35 ? 537 LEU A CB  1 
ATOM   2930  C  CG  . LEU A 1 538 ? 107.701 88.481  117.875 1.00 142.30 ? 537 LEU A CG  1 
ATOM   2931  C  CD1 . LEU A 1 538 ? 107.508 88.490  116.382 1.00 179.09 ? 537 LEU A CD1 1 
ATOM   2932  C  CD2 . LEU A 1 538 ? 107.432 87.095  118.457 1.00 132.24 ? 537 LEU A CD2 1 
ATOM   2933  N  N   . HIS A 1 539 ? 111.661 89.949  119.783 1.00 66.76  ? 538 HIS A N   1 
ATOM   2934  C  CA  . HIS A 1 539 ? 113.008 89.685  120.278 1.00 115.94 ? 538 HIS A CA  1 
ATOM   2935  C  C   . HIS A 1 539 ? 113.988 90.848  120.191 1.00 97.54  ? 538 HIS A C   1 
ATOM   2936  O  O   . HIS A 1 539 ? 115.227 90.647  120.282 1.00 106.78 ? 538 HIS A O   1 
ATOM   2937  C  CB  . HIS A 1 539 ? 113.621 88.438  119.602 1.00 220.59 ? 538 HIS A CB  1 
ATOM   2938  C  CG  . HIS A 1 539 ? 113.572 88.510  118.126 1.00 173.25 ? 538 HIS A CG  1 
ATOM   2939  N  ND1 . HIS A 1 539 ? 114.085 89.542  117.380 1.00 93.80  ? 538 HIS A ND1 1 
ATOM   2940  C  CD2 . HIS A 1 539 ? 113.019 87.627  117.309 1.00 198.79 ? 538 HIS A CD2 1 
ATOM   2941  C  CE1 . HIS A 1 539 ? 113.828 89.259  116.159 1.00 121.15 ? 538 HIS A CE1 1 
ATOM   2942  N  NE2 . HIS A 1 539 ? 113.188 88.111  116.080 1.00 193.49 ? 538 HIS A NE2 1 
ATOM   2943  N  N   . GLY A 1 540 ? 113.439 92.052  120.082 1.00 75.31  ? 539 GLY A N   1 
ATOM   2944  C  CA  . GLY A 1 540 ? 114.285 93.205  120.243 1.00 124.19 ? 539 GLY A CA  1 
ATOM   2945  C  C   . GLY A 1 540 ? 115.052 93.306  121.582 1.00 100.15 ? 539 GLY A C   1 
ATOM   2946  O  O   . GLY A 1 540 ? 114.840 92.589  122.549 1.00 133.10 ? 539 GLY A O   1 
ATOM   2947  N  N   . ASP A 1 541 ? 115.964 94.281  121.590 1.00 83.00  ? 540 ASP A N   1 
ATOM   2948  C  CA  . ASP A 1 541 ? 116.716 94.703  122.729 1.00 101.98 ? 540 ASP A CA  1 
ATOM   2949  C  C   . ASP A 1 541 ? 115.744 95.421  123.659 1.00 116.04 ? 540 ASP A C   1 
ATOM   2950  O  O   . ASP A 1 541 ? 114.571 95.570  123.323 1.00 75.22  ? 540 ASP A O   1 
ATOM   2951  C  CB  . ASP A 1 541 ? 117.865 95.576  122.253 1.00 137.43 ? 540 ASP A CB  1 
ATOM   2952  C  CG  . ASP A 1 541 ? 118.896 94.917  121.335 1.00 222.78 ? 540 ASP A CG  1 
ATOM   2953  O  OD1 . ASP A 1 541 ? 119.037 93.667  121.335 1.00 249.33 ? 540 ASP A OD1 1 
ATOM   2954  O  OD2 . ASP A 1 541 ? 119.558 95.675  120.600 1.00 265.33 ? 540 ASP A OD2 1 
ATOM   2955  N  N   . PHE A 1 542 ? 116.236 95.833  124.854 1.00 118.22 ? 541 PHE A N   1 
ATOM   2956  C  CA  . PHE A 1 542 ? 115.464 96.611  125.819 1.00 86.25  ? 541 PHE A CA  1 
ATOM   2957  C  C   . PHE A 1 542 ? 116.346 97.670  126.468 1.00 74.34  ? 541 PHE A C   1 
ATOM   2958  O  O   . PHE A 1 542 ? 117.423 97.328  126.920 1.00 100.99 ? 541 PHE A O   1 
ATOM   2959  C  CB  . PHE A 1 542 ? 114.891 95.648  126.855 1.00 80.47  ? 541 PHE A CB  1 
ATOM   2960  C  CG  . PHE A 1 542 ? 114.413 96.232  128.162 1.00 79.98  ? 541 PHE A CG  1 
ATOM   2961  C  CD1 . PHE A 1 542 ? 115.289 96.442  129.141 1.00 76.98  ? 541 PHE A CD1 1 
ATOM   2962  C  CD2 . PHE A 1 542 ? 113.095 96.562  128.436 1.00 97.44  ? 541 PHE A CD2 1 
ATOM   2963  C  CE1 . PHE A 1 542 ? 114.866 96.972  130.316 1.00 97.30  ? 541 PHE A CE1 1 
ATOM   2964  C  CE2 . PHE A 1 542 ? 112.686 97.097  129.629 1.00 49.08  ? 541 PHE A CE2 1 
ATOM   2965  C  CZ  . PHE A 1 542 ? 113.566 97.286  130.542 1.00 63.31  ? 541 PHE A CZ  1 
ATOM   2966  N  N   . HIS A 1 543 ? 115.909 98.931  126.495 1.00 83.36  ? 542 HIS A N   1 
ATOM   2967  C  CA  . HIS A 1 543 ? 116.664 100.002 127.114 1.00 104.49 ? 542 HIS A CA  1 
ATOM   2968  C  C   . HIS A 1 543 ? 115.720 100.768 128.011 1.00 98.09  ? 542 HIS A C   1 
ATOM   2969  O  O   . HIS A 1 543 ? 114.855 101.453 127.467 1.00 165.18 ? 542 HIS A O   1 
ATOM   2970  C  CB  . HIS A 1 543 ? 117.282 100.922 126.049 1.00 115.31 ? 542 HIS A CB  1 
ATOM   2971  C  CG  . HIS A 1 543 ? 118.463 100.254 125.429 1.00 179.10 ? 542 HIS A CG  1 
ATOM   2972  N  ND1 . HIS A 1 543 ? 118.521 99.730  124.147 1.00 143.58 ? 542 HIS A ND1 1 
ATOM   2973  C  CD2 . HIS A 1 543 ? 119.670 100.006 126.003 1.00 224.34 ? 542 HIS A CD2 1 
ATOM   2974  C  CE1 . HIS A 1 543 ? 119.735 99.205  123.958 1.00 211.64 ? 542 HIS A CE1 1 
ATOM   2975  N  NE2 . HIS A 1 543 ? 120.447 99.356  125.069 1.00 245.11 ? 542 HIS A NE2 1 
ATOM   2976  N  N   . ALA A 1 544 ? 115.921 100.664 129.325 1.00 69.42  ? 543 ALA A N   1 
ATOM   2977  C  CA  . ALA A 1 544 ? 115.236 101.531 130.257 1.00 74.82  ? 543 ALA A CA  1 
ATOM   2978  C  C   . ALA A 1 544 ? 115.798 102.929 130.281 1.00 89.87  ? 543 ALA A C   1 
ATOM   2979  O  O   . ALA A 1 544 ? 117.011 103.058 130.103 1.00 175.69 ? 543 ALA A O   1 
ATOM   2980  C  CB  . ALA A 1 544 ? 115.474 101.033 131.624 1.00 80.78  ? 543 ALA A CB  1 
ATOM   2981  N  N   . PHE A 1 545 ? 114.951 103.940 130.535 1.00 80.77  ? 544 PHE A N   1 
ATOM   2982  C  CA  . PHE A 1 545 ? 115.501 105.262 130.753 1.00 105.07 ? 544 PHE A CA  1 
ATOM   2983  C  C   . PHE A 1 545 ? 114.679 106.123 131.689 1.00 126.38 ? 544 PHE A C   1 
ATOM   2984  O  O   . PHE A 1 545 ? 113.522 105.773 131.953 1.00 106.27 ? 544 PHE A O   1 
ATOM   2985  C  CB  . PHE A 1 545 ? 115.632 105.882 129.390 1.00 90.23  ? 544 PHE A CB  1 
ATOM   2986  C  CG  . PHE A 1 545 ? 114.379 106.300 128.693 1.00 71.75  ? 544 PHE A CG  1 
ATOM   2987  C  CD1 . PHE A 1 545 ? 113.782 105.465 127.812 1.00 59.97  ? 544 PHE A CD1 1 
ATOM   2988  C  CD2 . PHE A 1 545 ? 113.877 107.583 128.872 1.00 102.88 ? 544 PHE A CD2 1 
ATOM   2989  C  CE1 . PHE A 1 545 ? 112.663 105.863 127.132 1.00 75.09  ? 544 PHE A CE1 1 
ATOM   2990  C  CE2 . PHE A 1 545 ? 112.754 107.978 128.193 1.00 100.23 ? 544 PHE A CE2 1 
ATOM   2991  C  CZ  . PHE A 1 545 ? 112.163 107.103 127.316 1.00 97.05  ? 544 PHE A CZ  1 
ATOM   2992  N  N   . SER A 1 546 ? 115.284 107.235 132.197 1.00 107.26 ? 545 SER A N   1 
ATOM   2993  C  CA  . SER A 1 546 ? 114.552 108.047 133.189 1.00 113.64 ? 545 SER A CA  1 
ATOM   2994  C  C   . SER A 1 546 ? 113.754 109.073 132.424 1.00 57.75  ? 545 SER A C   1 
ATOM   2995  O  O   . SER A 1 546 ? 114.308 110.007 131.891 1.00 141.74 ? 545 SER A O   1 
ATOM   2996  C  CB  . SER A 1 546 ? 115.394 108.665 134.274 1.00 142.44 ? 545 SER A CB  1 
ATOM   2997  O  OG  . SER A 1 546 ? 116.269 107.712 134.868 1.00 180.17 ? 545 SER A OG  1 
ATOM   2998  N  N   . ALA A 1 547 ? 112.483 108.860 132.288 1.00 69.03  ? 546 ALA A N   1 
ATOM   2999  C  CA  . ALA A 1 547 ? 111.644 109.633 131.384 1.00 85.71  ? 546 ALA A CA  1 
ATOM   3000  C  C   . ALA A 1 547 ? 110.879 110.668 132.152 1.00 66.44  ? 546 ALA A C   1 
ATOM   3001  O  O   . ALA A 1 547 ? 110.293 111.458 131.472 1.00 53.80  ? 546 ALA A O   1 
ATOM   3002  C  CB  . ALA A 1 547 ? 110.581 108.759 130.740 1.00 105.95 ? 546 ALA A CB  1 
ATOM   3003  N  N   . GLY A 1 548 ? 110.863 110.639 133.502 1.00 68.80  ? 547 GLY A N   1 
ATOM   3004  C  CA  . GLY A 1 548 ? 109.813 111.295 134.292 1.00 63.21  ? 547 GLY A CA  1 
ATOM   3005  C  C   . GLY A 1 548 ? 109.794 110.755 135.705 1.00 58.86  ? 547 GLY A C   1 
ATOM   3006  O  O   . GLY A 1 548 ? 110.496 109.763 135.910 1.00 79.43  ? 547 GLY A O   1 
ATOM   3007  N  N   . PRO A 1 549 ? 109.140 111.413 136.704 1.00 57.20  ? 548 PRO A N   1 
ATOM   3008  C  CA  . PRO A 1 549 ? 109.135 110.975 138.105 1.00 60.65  ? 548 PRO A CA  1 
ATOM   3009  C  C   . PRO A 1 549 ? 108.646 109.571 138.335 1.00 63.86  ? 548 PRO A C   1 
ATOM   3010  O  O   . PRO A 1 549 ? 109.544 108.762 138.623 1.00 82.11  ? 548 PRO A O   1 
ATOM   3011  C  CB  . PRO A 1 549 ? 108.527 112.135 138.895 1.00 37.57  ? 548 PRO A CB  1 
ATOM   3012  C  CG  . PRO A 1 549 ? 109.067 113.153 138.054 1.00 41.75  ? 548 PRO A CG  1 
ATOM   3013  C  CD  . PRO A 1 549 ? 108.564 112.738 136.679 1.00 55.04  ? 548 PRO A CD  1 
ATOM   3014  N  N   . GLY A 1 550 ? 107.375 109.280 138.218 1.00 64.49  ? 549 GLY A N   1 
ATOM   3015  C  CA  . GLY A 1 550 ? 107.009 107.878 138.490 1.00 127.23 ? 549 GLY A CA  1 
ATOM   3016  C  C   . GLY A 1 550 ? 107.400 106.820 137.429 1.00 75.15  ? 549 GLY A C   1 
ATOM   3017  O  O   . GLY A 1 550 ? 107.569 105.609 137.702 1.00 57.11  ? 549 GLY A O   1 
ATOM   3018  N  N   . LEU A 1 551 ? 107.531 107.327 136.222 1.00 47.14  ? 550 LEU A N   1 
ATOM   3019  C  CA  . LEU A 1 551 ? 107.463 106.519 135.056 1.00 49.02  ? 550 LEU A CA  1 
ATOM   3020  C  C   . LEU A 1 551 ? 108.591 105.482 135.099 1.00 58.20  ? 550 LEU A C   1 
ATOM   3021  O  O   . LEU A 1 551 ? 109.763 105.749 135.352 1.00 56.49  ? 550 LEU A O   1 
ATOM   3022  C  CB  . LEU A 1 551 ? 107.668 107.388 133.839 1.00 67.98  ? 550 LEU A CB  1 
ATOM   3023  C  CG  . LEU A 1 551 ? 106.881 108.682 133.734 1.00 72.21  ? 550 LEU A CG  1 
ATOM   3024  C  CD1 . LEU A 1 551 ? 107.310 109.391 132.404 1.00 88.67  ? 550 LEU A CD1 1 
ATOM   3025  C  CD2 . LEU A 1 551 ? 105.410 108.387 133.834 1.00 47.25  ? 550 LEU A CD2 1 
ATOM   3026  N  N   . PHE A 1 552 ? 108.193 104.244 134.855 1.00 57.85  ? 551 PHE A N   1 
ATOM   3027  C  CA  . PHE A 1 552 ? 109.047 103.214 134.311 1.00 46.92  ? 551 PHE A CA  1 
ATOM   3028  C  C   . PHE A 1 552 ? 108.934 103.346 132.829 1.00 41.98  ? 551 PHE A C   1 
ATOM   3029  O  O   . PHE A 1 552 ? 107.839 103.188 132.356 1.00 46.32  ? 551 PHE A O   1 
ATOM   3030  C  CB  . PHE A 1 552 ? 108.554 101.812 134.621 1.00 38.07  ? 551 PHE A CB  1 
ATOM   3031  C  CG  . PHE A 1 552 ? 109.378 100.643 134.195 1.00 40.97  ? 551 PHE A CG  1 
ATOM   3032  C  CD1 . PHE A 1 552 ? 110.713 100.710 133.875 1.00 62.38  ? 551 PHE A CD1 1 
ATOM   3033  C  CD2 . PHE A 1 552 ? 108.816 99.409  134.237 1.00 41.05  ? 551 PHE A CD2 1 
ATOM   3034  C  CE1 . PHE A 1 552 ? 111.477 99.603  133.535 1.00 59.24  ? 551 PHE A CE1 1 
ATOM   3035  C  CE2 . PHE A 1 552 ? 109.587 98.304  133.899 1.00 54.81  ? 551 PHE A CE2 1 
ATOM   3036  C  CZ  . PHE A 1 552 ? 110.924 98.396  133.548 1.00 52.60  ? 551 PHE A CZ  1 
ATOM   3037  N  N   . SER A 1 553 ? 110.021 103.644 132.158 1.00 47.79  ? 552 SER A N   1 
ATOM   3038  C  CA  . SER A 1 553 ? 109.899 103.801 130.753 1.00 60.26  ? 552 SER A CA  1 
ATOM   3039  C  C   . SER A 1 553 ? 111.043 103.134 130.015 1.00 69.19  ? 552 SER A C   1 
ATOM   3040  O  O   . SER A 1 553 ? 112.171 103.120 130.535 1.00 147.96 ? 552 SER A O   1 
ATOM   3041  C  CB  . SER A 1 553 ? 109.801 105.206 130.489 1.00 62.77  ? 552 SER A CB  1 
ATOM   3042  O  OG  . SER A 1 553 ? 109.668 105.269 129.075 1.00 85.57  ? 552 SER A OG  1 
ATOM   3043  N  N   . TYR A 1 554 ? 110.751 102.567 128.842 1.00 50.85  ? 553 TYR A N   1 
ATOM   3044  C  CA  . TYR A 1 554 ? 111.775 101.817 128.136 1.00 58.56  ? 553 TYR A CA  1 
ATOM   3045  C  C   . TYR A 1 554 ? 111.421 101.648 126.685 1.00 57.70  ? 553 TYR A C   1 
ATOM   3046  O  O   . TYR A 1 554 ? 110.276 101.672 126.357 1.00 71.57  ? 553 TYR A O   1 
ATOM   3047  C  CB  . TYR A 1 554 ? 112.004 100.376 128.620 1.00 62.36  ? 553 TYR A CB  1 
ATOM   3048  C  CG  . TYR A 1 554 ? 110.735 99.648  128.889 1.00 49.74  ? 553 TYR A CG  1 
ATOM   3049  C  CD1 . TYR A 1 554 ? 110.218 98.903  127.896 1.00 38.07  ? 553 TYR A CD1 1 
ATOM   3050  C  CD2 . TYR A 1 554 ? 110.104 99.717  130.089 1.00 52.01  ? 553 TYR A CD2 1 
ATOM   3051  C  CE1 . TYR A 1 554 ? 109.074 98.177  128.049 1.00 46.10  ? 553 TYR A CE1 1 
ATOM   3052  C  CE2 . TYR A 1 554 ? 108.949 98.984  130.256 1.00 83.39  ? 553 TYR A CE2 1 
ATOM   3053  C  CZ  . TYR A 1 554 ? 108.433 98.197  129.233 1.00 55.25  ? 553 TYR A CZ  1 
ATOM   3054  O  OH  . TYR A 1 554 ? 107.313 97.442  129.273 1.00 59.29  ? 553 TYR A OH  1 
ATOM   3055  N  N   . ILE A 1 555 ? 112.425 101.457 125.838 1.00 67.62  ? 554 ILE A N   1 
ATOM   3056  C  CA  . ILE A 1 555 ? 112.250 101.269 124.415 1.00 60.26  ? 554 ILE A CA  1 
ATOM   3057  C  C   . ILE A 1 555 ? 112.633 99.834  124.069 1.00 62.49  ? 554 ILE A C   1 
ATOM   3058  O  O   . ILE A 1 555 ? 113.675 99.342  124.490 1.00 79.72  ? 554 ILE A O   1 
ATOM   3059  C  CB  . ILE A 1 555 ? 113.138 102.238 123.693 1.00 57.56  ? 554 ILE A CB  1 
ATOM   3060  C  CG1 . ILE A 1 555 ? 112.640 103.654 123.906 1.00 73.63  ? 554 ILE A CG1 1 
ATOM   3061  C  CG2 . ILE A 1 555 ? 113.108 101.886 122.259 1.00 85.80  ? 554 ILE A CG2 1 
ATOM   3062  C  CD1 . ILE A 1 555 ? 113.661 104.672 123.456 1.00 141.20 ? 554 ILE A CD1 1 
ATOM   3063  N  N   . ARG A 1 556 ? 111.761 99.169  123.327 1.00 55.37  ? 555 ARG A N   1 
ATOM   3064  C  CA  . ARG A 1 556 ? 112.088 97.917  122.711 1.00 66.24  ? 555 ARG A CA  1 
ATOM   3065  C  C   . ARG A 1 556 ? 112.443 98.209  121.252 1.00 102.01 ? 555 ARG A C   1 
ATOM   3066  O  O   . ARG A 1 556 ? 111.695 98.932  120.565 1.00 89.81  ? 555 ARG A O   1 
ATOM   3067  C  CB  . ARG A 1 556 ? 110.874 96.987  122.718 1.00 64.85  ? 555 ARG A CB  1 
ATOM   3068  C  CG  . ARG A 1 556 ? 110.372 96.502  124.045 1.00 44.91  ? 555 ARG A CG  1 
ATOM   3069  C  CD  . ARG A 1 556 ? 111.489 95.867  124.801 1.00 43.95  ? 555 ARG A CD  1 
ATOM   3070  N  NE  . ARG A 1 556 ? 111.987 94.723  124.125 1.00 56.10  ? 555 ARG A NE  1 
ATOM   3071  C  CZ  . ARG A 1 556 ? 111.409 93.521  124.036 1.00 61.96  ? 555 ARG A CZ  1 
ATOM   3072  N  NH1 . ARG A 1 556 ? 112.051 92.516  123.500 1.00 80.00  ? 555 ARG A NH1 1 
ATOM   3073  N  NH2 . ARG A 1 556 ? 110.212 93.256  124.462 1.00 78.02  ? 555 ARG A NH2 1 
ATOM   3074  N  N   . HIS A 1 557 ? 113.563 97.632  120.765 1.00 95.25  ? 556 HIS A N   1 
ATOM   3075  C  CA  . HIS A 1 557 ? 113.932 97.844  119.382 1.00 86.90  ? 556 HIS A CA  1 
ATOM   3076  C  C   . HIS A 1 557 ? 114.682 96.681  118.781 1.00 113.08 ? 556 HIS A C   1 
ATOM   3077  O  O   . HIS A 1 557 ? 115.308 95.979  119.542 1.00 136.15 ? 556 HIS A O   1 
ATOM   3078  C  CB  . HIS A 1 557 ? 114.815 99.082  119.220 1.00 108.30 ? 556 HIS A CB  1 
ATOM   3079  C  CG  . HIS A 1 557 ? 116.084 99.147  119.968 1.00 121.03 ? 556 HIS A CG  1 
ATOM   3080  N  ND1 . HIS A 1 557 ? 117.174 98.373  119.712 1.00 133.21 ? 556 HIS A ND1 1 
ATOM   3081  C  CD2 . HIS A 1 557 ? 116.410 99.944  120.993 1.00 182.35 ? 556 HIS A CD2 1 
ATOM   3082  C  CE1 . HIS A 1 557 ? 118.121 98.710  120.584 1.00 170.73 ? 556 HIS A CE1 1 
ATOM   3083  N  NE2 . HIS A 1 557 ? 117.681 99.657  121.368 1.00 148.14 ? 556 HIS A NE2 1 
ATOM   3084  N  N   . TRP A 1 558 ? 114.637 96.543  117.427 1.00 156.07 ? 557 TRP A N   1 
ATOM   3085  C  CA  . TRP A 1 558 ? 115.448 95.636  116.606 1.00 125.18 ? 557 TRP A CA  1 
ATOM   3086  C  C   . TRP A 1 558 ? 115.955 96.322  115.360 1.00 131.52 ? 557 TRP A C   1 
ATOM   3087  O  O   . TRP A 1 558 ? 115.451 97.415  115.071 1.00 188.08 ? 557 TRP A O   1 
ATOM   3088  C  CB  . TRP A 1 558 ? 114.568 94.486  116.204 1.00 89.58  ? 557 TRP A CB  1 
ATOM   3089  C  CG  . TRP A 1 558 ? 115.262 93.329  115.529 1.00 107.25 ? 557 TRP A CG  1 
ATOM   3090  C  CD1 . TRP A 1 558 ? 114.808 92.787  114.383 1.00 130.57 ? 557 TRP A CD1 1 
ATOM   3091  C  CD2 . TRP A 1 558 ? 116.407 92.523  115.902 1.00 105.00 ? 557 TRP A CD2 1 
ATOM   3092  N  NE1 . TRP A 1 558 ? 115.579 91.732  113.991 1.00 119.34 ? 557 TRP A NE1 1 
ATOM   3093  C  CE2 . TRP A 1 558 ? 116.558 91.534  114.917 1.00 115.36 ? 557 TRP A CE2 1 
ATOM   3094  C  CE3 . TRP A 1 558 ? 117.298 92.518  116.963 1.00 136.53 ? 557 TRP A CE3 1 
ATOM   3095  C  CZ2 . TRP A 1 558 ? 117.560 90.580  114.966 1.00 128.20 ? 557 TRP A CZ2 1 
ATOM   3096  C  CZ3 . TRP A 1 558 ? 118.284 91.569  117.026 1.00 160.34 ? 557 TRP A CZ3 1 
ATOM   3097  C  CH2 . TRP A 1 558 ? 118.408 90.611  116.044 1.00 153.28 ? 557 TRP A CH2 1 
ATOM   3098  N  N   . ASP A 1 559 ? 116.906 95.708  114.649 1.00 120.73 ? 558 ASP A N   1 
ATOM   3099  C  CA  . ASP A 1 559 ? 117.893 96.455  113.887 1.00 213.95 ? 558 ASP A CA  1 
ATOM   3100  C  C   . ASP A 1 559 ? 117.302 97.652  113.131 1.00 194.81 ? 558 ASP A C   1 
ATOM   3101  O  O   . ASP A 1 559 ? 117.836 98.765  113.334 1.00 271.33 ? 558 ASP A O   1 
ATOM   3102  C  CB  . ASP A 1 559 ? 118.750 95.571  112.973 1.00 259.86 ? 558 ASP A CB  1 
ATOM   3103  C  CG  . ASP A 1 559 ? 118.080 94.737  111.898 1.00 236.18 ? 558 ASP A CG  1 
ATOM   3104  O  OD1 . ASP A 1 559 ? 116.869 94.943  111.623 1.00 157.01 ? 558 ASP A OD1 1 
ATOM   3105  O  OD2 . ASP A 1 559 ? 118.807 93.883  111.330 1.00 302.55 ? 558 ASP A OD2 1 
ATOM   3106  N  N   . GLN A 1 560 ? 116.257 97.456  112.274 1.00 99.52  ? 559 GLN A N   1 
ATOM   3107  C  CA  . GLN A 1 560 ? 115.688 98.628  111.584 1.00 127.29 ? 559 GLN A CA  1 
ATOM   3108  C  C   . GLN A 1 560 ? 114.180 98.649  111.644 1.00 105.81 ? 559 GLN A C   1 
ATOM   3109  O  O   . GLN A 1 560 ? 113.564 99.576  111.114 1.00 117.67 ? 559 GLN A O   1 
ATOM   3110  C  CB  . GLN A 1 560 ? 116.150 98.766  110.121 1.00 143.10 ? 559 GLN A CB  1 
ATOM   3111  C  CG  . GLN A 1 560 ? 117.684 98.836  109.983 1.00 209.95 ? 559 GLN A CG  1 
ATOM   3112  C  CD  . GLN A 1 560 ? 118.138 99.190  108.592 1.00 168.99 ? 559 GLN A CD  1 
ATOM   3113  O  OE1 . GLN A 1 560 ? 117.358 99.769  107.841 1.00 152.81 ? 559 GLN A OE1 1 
ATOM   3114  N  NE2 . GLN A 1 560 ? 119.381 98.845  108.236 1.00 200.98 ? 559 GLN A NE2 1 
ATOM   3115  N  N   . ASN A 1 561 ? 113.584 97.624  112.262 1.00 96.22  ? 560 ASN A N   1 
ATOM   3116  C  CA  . ASN A 1 561 ? 112.131 97.534  112.224 1.00 142.23 ? 560 ASN A CA  1 
ATOM   3117  C  C   . ASN A 1 561 ? 111.556 98.637  113.139 1.00 141.29 ? 560 ASN A C   1 
ATOM   3118  O  O   . ASN A 1 561 ? 112.301 99.414  113.737 1.00 116.59 ? 560 ASN A O   1 
ATOM   3119  C  CB  . ASN A 1 561 ? 111.691 96.093  112.538 1.00 130.06 ? 560 ASN A CB  1 
ATOM   3120  C  CG  . ASN A 1 561 ? 112.252 94.974  111.673 1.00 129.30 ? 560 ASN A CG  1 
ATOM   3121  O  OD1 . ASN A 1 561 ? 112.196 93.827  112.060 1.00 140.97 ? 560 ASN A OD1 1 
ATOM   3122  N  ND2 . ASN A 1 561 ? 112.760 95.205  110.472 1.00 214.02 ? 560 ASN A ND2 1 
ATOM   3123  N  N   . GLU A 1 562 ? 110.221 98.682  113.284 1.00 155.22 ? 561 GLU A N   1 
ATOM   3124  C  CA  . GLU A 1 562 ? 109.539 99.610  114.181 1.00 153.95 ? 561 GLU A CA  1 
ATOM   3125  C  C   . GLU A 1 562 ? 110.059 99.583  115.629 1.00 163.06 ? 561 GLU A C   1 
ATOM   3126  O  O   . GLU A 1 562 ? 110.358 98.519  116.169 1.00 180.23 ? 561 GLU A O   1 
ATOM   3127  C  CB  . GLU A 1 562 ? 108.045 99.290  114.251 1.00 151.00 ? 561 GLU A CB  1 
ATOM   3128  C  CG  . GLU A 1 562 ? 107.194 100.525 114.439 1.00 186.16 ? 561 GLU A CG  1 
ATOM   3129  C  CD  . GLU A 1 562 ? 106.918 101.321 113.164 1.00 306.23 ? 561 GLU A CD  1 
ATOM   3130  O  OE1 . GLU A 1 562 ? 107.840 101.503 112.329 1.00 378.15 ? 561 GLU A OE1 1 
ATOM   3131  O  OE2 . GLU A 1 562 ? 105.766 101.772 112.992 1.00 351.11 ? 561 GLU A OE2 1 
ATOM   3132  N  N   . ARG A 1 563 ? 110.153 100.772 116.270 1.00 143.70 ? 562 ARG A N   1 
ATOM   3133  C  CA  . ARG A 1 563 ? 110.679 100.908 117.633 1.00 101.23 ? 562 ARG A CA  1 
ATOM   3134  C  C   . ARG A 1 563 ? 109.526 101.252 118.557 1.00 83.25  ? 562 ARG A C   1 
ATOM   3135  O  O   . ARG A 1 563 ? 108.712 102.040 118.200 1.00 87.27  ? 562 ARG A O   1 
ATOM   3136  C  CB  . ARG A 1 563 ? 111.877 101.843 117.611 1.00 72.50  ? 562 ARG A CB  1 
ATOM   3137  C  CG  . ARG A 1 563 ? 112.994 101.304 116.707 1.00 132.34 ? 562 ARG A CG  1 
ATOM   3138  C  CD  . ARG A 1 563 ? 114.514 101.521 116.902 1.00 104.55 ? 562 ARG A CD  1 
ATOM   3139  N  NE  . ARG A 1 563 ? 114.771 102.926 117.032 1.00 126.30 ? 562 ARG A NE  1 
ATOM   3140  C  CZ  . ARG A 1 563 ? 115.966 103.445 117.050 1.00 176.73 ? 562 ARG A CZ  1 
ATOM   3141  N  NH1 . ARG A 1 563 ? 116.103 104.733 116.744 1.00 179.32 ? 562 ARG A NH1 1 
ATOM   3142  N  NH2 . ARG A 1 563 ? 116.984 102.636 117.330 1.00 191.60 ? 562 ARG A NH2 1 
ATOM   3143  N  N   . PHE A 1 564 ? 109.428 100.608 119.723 1.00 84.11  ? 563 PHE A N   1 
ATOM   3144  C  CA  . PHE A 1 564 ? 108.293 100.766 120.616 1.00 73.70  ? 563 PHE A CA  1 
ATOM   3145  C  C   . PHE A 1 564 ? 108.778 101.305 121.946 1.00 87.32  ? 563 PHE A C   1 
ATOM   3146  O  O   . PHE A 1 564 ? 109.592 100.690 122.600 1.00 86.50  ? 563 PHE A O   1 
ATOM   3147  C  CB  . PHE A 1 564 ? 107.630 99.450  120.944 1.00 98.37  ? 563 PHE A CB  1 
ATOM   3148  C  CG  . PHE A 1 564 ? 106.882 98.835  119.812 1.00 90.67  ? 563 PHE A CG  1 
ATOM   3149  C  CD1 . PHE A 1 564 ? 107.576 98.229  118.811 1.00 96.91  ? 563 PHE A CD1 1 
ATOM   3150  C  CD2 . PHE A 1 564 ? 105.521 98.855  119.788 1.00 90.67  ? 563 PHE A CD2 1 
ATOM   3151  C  CE1 . PHE A 1 564 ? 106.900 97.647  117.772 1.00 146.54 ? 563 PHE A CE1 1 
ATOM   3152  C  CE2 . PHE A 1 564 ? 104.844 98.268  118.764 1.00 112.69 ? 563 PHE A CE2 1 
ATOM   3153  C  CZ  . PHE A 1 564 ? 105.526 97.667  117.749 1.00 185.38 ? 563 PHE A CZ  1 
ATOM   3154  N  N   . LEU A 1 565 ? 108.256 102.455 122.336 1.00 94.01  ? 564 LEU A N   1 
ATOM   3155  C  CA  . LEU A 1 565 ? 108.522 103.089 123.612 1.00 70.09  ? 564 LEU A CA  1 
ATOM   3156  C  C   . LEU A 1 565 ? 107.315 102.777 124.478 1.00 54.13  ? 564 LEU A C   1 
ATOM   3157  O  O   . LEU A 1 565 ? 106.215 102.967 124.042 1.00 59.00  ? 564 LEU A O   1 
ATOM   3158  C  CB  . LEU A 1 565 ? 108.660 104.585 123.375 1.00 67.89  ? 564 LEU A CB  1 
ATOM   3159  C  CG  . LEU A 1 565 ? 108.378 105.517 124.530 1.00 70.30  ? 564 LEU A CG  1 
ATOM   3160  C  CD1 . LEU A 1 565 ? 109.451 105.376 125.572 1.00 81.18  ? 564 LEU A CD1 1 
ATOM   3161  C  CD2 . LEU A 1 565 ? 108.355 106.923 124.035 1.00 77.66  ? 564 LEU A CD2 1 
ATOM   3162  N  N   . VAL A 1 566 ? 107.551 102.298 125.687 1.00 57.01  ? 565 VAL A N   1 
ATOM   3163  C  CA  . VAL A 1 566 ? 106.538 102.026 126.675 1.00 53.26  ? 565 VAL A CA  1 
ATOM   3164  C  C   . VAL A 1 566 ? 106.718 102.993 127.814 1.00 55.37  ? 565 VAL A C   1 
ATOM   3165  O  O   . VAL A 1 566 ? 107.841 103.298 128.191 1.00 93.92  ? 565 VAL A O   1 
ATOM   3166  C  CB  . VAL A 1 566 ? 106.650 100.577 127.176 1.00 51.01  ? 565 VAL A CB  1 
ATOM   3167  C  CG1 . VAL A 1 566 ? 105.558 100.373 128.202 1.00 65.58  ? 565 VAL A CG1 1 
ATOM   3168  C  CG2 . VAL A 1 566 ? 106.509 99.543  126.053 1.00 44.33  ? 565 VAL A CG2 1 
ATOM   3169  N  N   . VAL A 1 567 ? 105.630 103.469 128.387 1.00 55.77  ? 566 VAL A N   1 
ATOM   3170  C  CA  . VAL A 1 567 ? 105.730 104.514 129.391 1.00 53.62  ? 566 VAL A CA  1 
ATOM   3171  C  C   . VAL A 1 567 ? 104.662 104.171 130.400 1.00 44.46  ? 566 VAL A C   1 
ATOM   3172  O  O   . VAL A 1 567 ? 103.499 104.373 130.149 1.00 72.76  ? 566 VAL A O   1 
ATOM   3173  C  CB  . VAL A 1 567 ? 105.484 105.935 128.813 1.00 65.52  ? 566 VAL A CB  1 
ATOM   3174  C  CG1 . VAL A 1 567 ? 105.539 106.976 129.931 1.00 78.30  ? 566 VAL A CG1 1 
ATOM   3175  C  CG2 . VAL A 1 567 ? 106.336 106.291 127.576 1.00 54.35  ? 566 VAL A CG2 1 
ATOM   3176  N  N   . LEU A 1 568 ? 105.063 103.673 131.531 1.00 51.21  ? 567 LEU A N   1 
ATOM   3177  C  CA  . LEU A 1 568 ? 104.139 103.206 132.547 1.00 72.21  ? 567 LEU A CA  1 
ATOM   3178  C  C   . LEU A 1 568 ? 104.158 104.195 133.709 1.00 51.31  ? 567 LEU A C   1 
ATOM   3179  O  O   . LEU A 1 568 ? 105.191 104.388 134.281 1.00 40.21  ? 567 LEU A O   1 
ATOM   3180  C  CB  . LEU A 1 568 ? 104.526 101.779 132.988 1.00 55.67  ? 567 LEU A CB  1 
ATOM   3181  C  CG  . LEU A 1 568 ? 104.652 100.789 131.840 1.00 54.15  ? 567 LEU A CG  1 
ATOM   3182  C  CD1 . LEU A 1 568 ? 105.674 99.747  132.144 1.00 60.55  ? 567 LEU A CD1 1 
ATOM   3183  C  CD2 . LEU A 1 568 ? 103.371 100.104 131.643 1.00 91.08  ? 567 LEU A CD2 1 
ATOM   3184  N  N   . ASN A 1 569 ? 103.022 104.778 134.075 1.00 49.21  ? 568 ASN A N   1 
ATOM   3185  C  CA  . ASN A 1 569 ? 103.059 105.705 135.173 1.00 62.00  ? 568 ASN A CA  1 
ATOM   3186  C  C   . ASN A 1 569 ? 102.661 105.012 136.447 1.00 55.77  ? 568 ASN A C   1 
ATOM   3187  O  O   . ASN A 1 569 ? 101.494 105.023 136.764 1.00 60.58  ? 568 ASN A O   1 
ATOM   3188  C  CB  . ASN A 1 569 ? 102.155 106.902 134.950 1.00 70.28  ? 568 ASN A CB  1 
ATOM   3189  C  CG  . ASN A 1 569 ? 102.252 107.932 136.062 1.00 59.10  ? 568 ASN A CG  1 
ATOM   3190  O  OD1 . ASN A 1 569 ? 103.178 108.005 136.842 1.00 40.77  ? 568 ASN A OD1 1 
ATOM   3191  N  ND2 . ASN A 1 569 ? 101.240 108.748 136.147 1.00 90.96  ? 568 ASN A ND2 1 
ATOM   3192  N  N   . PHE A 1 570 ? 103.624 104.457 137.185 1.00 55.24  ? 569 PHE A N   1 
ATOM   3193  C  CA  . PHE A 1 570 ? 103.275 103.658 138.321 1.00 63.40  ? 569 PHE A CA  1 
ATOM   3194  C  C   . PHE A 1 570 ? 102.834 104.499 139.496 1.00 85.58  ? 569 PHE A C   1 
ATOM   3195  O  O   . PHE A 1 570 ? 101.894 104.093 140.197 1.00 85.80  ? 569 PHE A O   1 
ATOM   3196  C  CB  . PHE A 1 570 ? 104.439 102.751 138.689 1.00 80.34  ? 569 PHE A CB  1 
ATOM   3197  C  CG  . PHE A 1 570 ? 104.487 101.473 137.898 1.00 66.88  ? 569 PHE A CG  1 
ATOM   3198  C  CD1 . PHE A 1 570 ? 103.542 100.534 138.085 1.00 60.64  ? 569 PHE A CD1 1 
ATOM   3199  C  CD2 . PHE A 1 570 ? 105.495 101.222 136.992 1.00 86.15  ? 569 PHE A CD2 1 
ATOM   3200  C  CE1 . PHE A 1 570 ? 103.624 99.378  137.357 1.00 96.88  ? 569 PHE A CE1 1 
ATOM   3201  C  CE2 . PHE A 1 570 ? 105.561 100.074 136.256 1.00 73.35  ? 569 PHE A CE2 1 
ATOM   3202  C  CZ  . PHE A 1 570 ? 104.607 99.157  136.428 1.00 101.62 ? 569 PHE A CZ  1 
ATOM   3203  N  N   . GLY A 1 571 ? 103.491 105.620 139.739 1.00 80.44  ? 570 GLY A N   1 
ATOM   3204  C  CA  . GLY A 1 571 ? 102.978 106.434 140.830 1.00 119.58 ? 570 GLY A CA  1 
ATOM   3205  C  C   . GLY A 1 571 ? 101.572 107.022 140.586 1.00 78.56  ? 570 GLY A C   1 
ATOM   3206  O  O   . GLY A 1 571 ? 101.184 107.258 139.450 1.00 45.15  ? 570 GLY A O   1 
ATOM   3207  N  N   . ASP A 1 572 ? 100.875 107.356 141.685 1.00 79.06  ? 571 ASP A N   1 
ATOM   3208  C  CA  . ASP A 1 572 ? 99.499  107.832 141.663 1.00 83.72  ? 571 ASP A CA  1 
ATOM   3209  C  C   . ASP A 1 572 ? 99.275  109.306 141.328 1.00 78.10  ? 571 ASP A C   1 
ATOM   3210  O  O   . ASP A 1 572 ? 98.192  109.796 141.571 1.00 81.88  ? 571 ASP A O   1 
ATOM   3211  C  CB  . ASP A 1 572 ? 98.819  107.587 143.010 1.00 93.09  ? 571 ASP A CB  1 
ATOM   3212  C  CG  . ASP A 1 572 ? 99.510  108.299 144.176 1.00 129.74 ? 571 ASP A CG  1 
ATOM   3213  O  OD1 . ASP A 1 572 ? 100.605 107.814 144.518 1.00 238.72 ? 571 ASP A OD1 1 
ATOM   3214  O  OD2 . ASP A 1 572 ? 98.975  109.294 144.730 1.00 153.56 ? 571 ASP A OD2 1 
ATOM   3215  N  N   . VAL A 1 573 ? 100.241 109.994 140.737 1.00 85.98  ? 572 VAL A N   1 
ATOM   3216  C  CA  . VAL A 1 573 ? 100.164 111.399 140.465 1.00 58.80  ? 572 VAL A CA  1 
ATOM   3217  C  C   . VAL A 1 573 ? 100.359 111.556 138.988 1.00 60.46  ? 572 VAL A C   1 
ATOM   3218  O  O   . VAL A 1 573 ? 101.364 111.059 138.474 1.00 74.67  ? 572 VAL A O   1 
ATOM   3219  C  CB  . VAL A 1 573 ? 101.331 112.098 141.177 1.00 74.67  ? 572 VAL A CB  1 
ATOM   3220  C  CG1 . VAL A 1 573 ? 100.952 113.572 141.156 1.00 96.15  ? 572 VAL A CG1 1 
ATOM   3221  C  CG2 . VAL A 1 573 ? 101.654 111.547 142.609 1.00 76.62  ? 572 VAL A CG2 1 
ATOM   3222  N  N   . GLY A 1 574 ? 99.500  112.276 138.307 1.00 63.86  ? 573 GLY A N   1 
ATOM   3223  C  CA  . GLY A 1 574 ? 99.718  112.476 136.869 1.00 83.46  ? 573 GLY A CA  1 
ATOM   3224  C  C   . GLY A 1 574 ? 100.914 113.363 136.500 1.00 72.34  ? 573 GLY A C   1 
ATOM   3225  O  O   . GLY A 1 574 ? 101.323 114.187 137.302 1.00 86.20  ? 573 GLY A O   1 
ATOM   3226  N  N   . LEU A 1 575 ? 101.440 113.214 135.290 1.00 63.24  ? 574 LEU A N   1 
ATOM   3227  C  CA  . LEU A 1 575 ? 102.452 114.132 134.822 1.00 73.41  ? 574 LEU A CA  1 
ATOM   3228  C  C   . LEU A 1 575 ? 101.873 115.129 133.824 1.00 86.00  ? 574 LEU A C   1 
ATOM   3229  O  O   . LEU A 1 575 ? 101.005 114.811 133.011 1.00 116.84 ? 574 LEU A O   1 
ATOM   3230  C  CB  . LEU A 1 575 ? 103.587 113.359 134.172 1.00 71.02  ? 574 LEU A CB  1 
ATOM   3231  C  CG  . LEU A 1 575 ? 104.259 112.324 135.072 1.00 91.15  ? 574 LEU A CG  1 
ATOM   3232  C  CD1 . LEU A 1 575 ? 105.589 112.003 134.448 1.00 129.19 ? 574 LEU A CD1 1 
ATOM   3233  C  CD2 . LEU A 1 575 ? 104.488 112.726 136.512 1.00 83.57  ? 574 LEU A CD2 1 
ATOM   3234  N  N   . SER A 1 576 ? 102.395 116.354 133.898 1.00 89.98  ? 575 SER A N   1 
ATOM   3235  C  CA  . SER A 1 576 ? 101.794 117.488 133.249 1.00 105.33 ? 575 SER A CA  1 
ATOM   3236  C  C   . SER A 1 576 ? 102.801 118.283 132.399 1.00 93.64  ? 575 SER A C   1 
ATOM   3237  O  O   . SER A 1 576 ? 102.586 119.459 132.103 1.00 154.08 ? 575 SER A O   1 
ATOM   3238  C  CB  . SER A 1 576 ? 101.064 118.274 134.341 1.00 135.70 ? 575 SER A CB  1 
ATOM   3239  O  OG  . SER A 1 576 ? 100.279 119.291 133.723 1.00 236.84 ? 575 SER A OG  1 
ATOM   3240  N  N   . ALA A 1 577 ? 103.883 117.641 131.994 1.00 89.62  ? 576 ALA A N   1 
ATOM   3241  C  CA  . ALA A 1 577 ? 105.092 118.327 131.551 1.00 114.66 ? 576 ALA A CA  1 
ATOM   3242  C  C   . ALA A 1 577 ? 105.897 117.489 130.565 1.00 87.29  ? 576 ALA A C   1 
ATOM   3243  O  O   . ALA A 1 577 ? 107.073 117.706 130.351 1.00 71.84  ? 576 ALA A O   1 
ATOM   3244  C  CB  . ALA A 1 577 ? 105.860 118.664 132.809 1.00 87.29  ? 576 ALA A CB  1 
ATOM   3245  N  N   . GLY A 1 578 ? 105.229 116.543 129.938 1.00 104.71 ? 577 GLY A N   1 
ATOM   3246  C  CA  . GLY A 1 578 ? 105.882 115.623 129.028 1.00 128.83 ? 577 GLY A CA  1 
ATOM   3247  C  C   . GLY A 1 578 ? 106.793 114.573 129.646 1.00 67.94  ? 577 GLY A C   1 
ATOM   3248  O  O   . GLY A 1 578 ? 107.010 114.545 130.835 1.00 84.96  ? 577 GLY A O   1 
ATOM   3249  N  N   . LEU A 1 579 ? 107.236 113.675 128.765 1.00 50.74  ? 578 LEU A N   1 
ATOM   3250  C  CA  . LEU A 1 579 ? 108.500 112.987 128.921 1.00 73.30  ? 578 LEU A CA  1 
ATOM   3251  C  C   . LEU A 1 579 ? 109.588 114.031 128.908 1.00 80.19  ? 578 LEU A C   1 
ATOM   3252  O  O   . LEU A 1 579 ? 109.475 115.044 128.239 1.00 107.67 ? 578 LEU A O   1 
ATOM   3253  C  CB  . LEU A 1 579 ? 108.802 111.949 127.836 1.00 64.95  ? 578 LEU A CB  1 
ATOM   3254  C  CG  . LEU A 1 579 ? 108.106 110.609 128.085 1.00 77.01  ? 578 LEU A CG  1 
ATOM   3255  C  CD1 . LEU A 1 579 ? 106.626 110.790 128.625 1.00 53.53  ? 578 LEU A CD1 1 
ATOM   3256  C  CD2 . LEU A 1 579 ? 108.288 109.730 126.804 1.00 62.70  ? 578 LEU A CD2 1 
ATOM   3257  N  N   . GLN A 1 580 ? 110.642 113.733 129.668 1.00 75.86  ? 579 GLN A N   1 
ATOM   3258  C  CA  . GLN A 1 580 ? 111.833 114.506 129.527 1.00 99.11  ? 579 GLN A CA  1 
ATOM   3259  C  C   . GLN A 1 580 ? 112.945 113.530 129.879 1.00 81.80  ? 579 GLN A C   1 
ATOM   3260  O  O   . GLN A 1 580 ? 113.406 113.558 130.994 1.00 78.74  ? 579 GLN A O   1 
ATOM   3261  C  CB  . GLN A 1 580 ? 111.660 115.875 130.225 1.00 94.47  ? 579 GLN A CB  1 
ATOM   3262  C  CG  . GLN A 1 580 ? 110.809 115.918 131.447 1.00 79.72  ? 579 GLN A CG  1 
ATOM   3263  C  CD  . GLN A 1 580 ? 110.740 117.248 132.180 1.00 113.56 ? 579 GLN A CD  1 
ATOM   3264  O  OE1 . GLN A 1 580 ? 109.703 117.696 132.677 1.00 54.34  ? 579 GLN A OE1 1 
ATOM   3265  N  NE2 . GLN A 1 580 ? 111.882 117.901 132.311 1.00 155.17 ? 579 GLN A NE2 1 
ATOM   3266  N  N   . ALA A 1 581 ? 113.348 112.746 128.859 1.00 103.06 ? 580 ALA A N   1 
ATOM   3267  C  CA  . ALA A 1 581 ? 114.412 111.759 128.896 1.00 124.72 ? 580 ALA A CA  1 
ATOM   3268  C  C   . ALA A 1 581 ? 115.798 112.366 129.163 1.00 127.79 ? 580 ALA A C   1 
ATOM   3269  O  O   . ALA A 1 581 ? 116.355 113.110 128.377 1.00 131.18 ? 580 ALA A O   1 
ATOM   3270  C  CB  . ALA A 1 581 ? 114.428 111.019 127.588 1.00 172.50 ? 580 ALA A CB  1 
ATOM   3271  N  N   . SER A 1 582 ? 116.369 112.038 130.312 1.00 154.25 ? 581 SER A N   1 
ATOM   3272  C  CA  . SER A 1 582 ? 117.809 112.078 130.504 1.00 174.38 ? 581 SER A CA  1 
ATOM   3273  C  C   . SER A 1 582 ? 118.443 110.845 129.867 1.00 215.71 ? 581 SER A C   1 
ATOM   3274  O  O   . SER A 1 582 ? 117.962 109.728 130.088 1.00 191.50 ? 581 SER A O   1 
ATOM   3275  C  CB  . SER A 1 582 ? 118.127 112.132 131.980 1.00 255.94 ? 581 SER A CB  1 
ATOM   3276  O  OG  . SER A 1 582 ? 119.521 112.055 132.247 1.00 314.53 ? 581 SER A OG  1 
ATOM   3277  N  N   . ASP A 1 583 ? 119.525 111.058 129.097 1.00 241.39 ? 582 ASP A N   1 
ATOM   3278  C  CA  . ASP A 1 583 ? 120.587 110.065 128.883 1.00 269.75 ? 582 ASP A CA  1 
ATOM   3279  C  C   . ASP A 1 583 ? 120.089 108.804 128.170 1.00 237.78 ? 582 ASP A C   1 
ATOM   3280  O  O   . ASP A 1 583 ? 120.197 107.673 128.667 1.00 265.29 ? 582 ASP A O   1 
ATOM   3281  C  CB  . ASP A 1 583 ? 121.265 109.662 130.200 1.00 381.25 ? 582 ASP A CB  1 
ATOM   3282  C  CG  . ASP A 1 583 ? 122.511 108.789 130.065 1.00 455.26 ? 582 ASP A CG  1 
ATOM   3283  O  OD1 . ASP A 1 583 ? 123.093 108.724 128.957 1.00 461.11 ? 582 ASP A OD1 1 
ATOM   3284  O  OD2 . ASP A 1 583 ? 122.888 108.170 131.077 1.00 539.71 ? 582 ASP A OD2 1 
ATOM   3285  N  N   . LEU A 1 584 ? 119.536 109.003 126.977 1.00 225.27 ? 583 LEU A N   1 
ATOM   3286  C  CA  . LEU A 1 584 ? 119.215 107.883 126.108 1.00 212.55 ? 583 LEU A CA  1 
ATOM   3287  C  C   . LEU A 1 584 ? 120.483 107.336 125.471 1.00 276.16 ? 583 LEU A C   1 
ATOM   3288  O  O   . LEU A 1 584 ? 121.395 108.115 125.174 1.00 269.11 ? 583 LEU A O   1 
ATOM   3289  C  CB  . LEU A 1 584 ? 118.251 108.375 125.041 1.00 188.86 ? 583 LEU A CB  1 
ATOM   3290  C  CG  . LEU A 1 584 ? 116.842 108.549 125.580 1.00 188.56 ? 583 LEU A CG  1 
ATOM   3291  C  CD1 . LEU A 1 584 ? 116.171 109.709 124.856 1.00 206.06 ? 583 LEU A CD1 1 
ATOM   3292  C  CD2 . LEU A 1 584 ? 116.124 107.198 125.471 1.00 114.33 ? 583 LEU A CD2 1 
ATOM   3293  N  N   . PRO A 1 585 ? 120.568 106.003 125.231 1.00 315.10 ? 584 PRO A N   1 
ATOM   3294  C  CA  . PRO A 1 585 ? 121.619 105.454 124.366 1.00 296.25 ? 584 PRO A CA  1 
ATOM   3295  C  C   . PRO A 1 585 ? 121.584 106.121 122.983 1.00 271.02 ? 584 PRO A C   1 
ATOM   3296  O  O   . PRO A 1 585 ? 120.510 106.364 122.431 1.00 255.54 ? 584 PRO A O   1 
ATOM   3297  C  CB  . PRO A 1 585 ? 121.318 103.943 124.288 1.00 311.47 ? 584 PRO A CB  1 
ATOM   3298  C  CG  . PRO A 1 585 ? 120.265 103.632 125.393 1.00 330.31 ? 584 PRO A CG  1 
ATOM   3299  C  CD  . PRO A 1 585 ? 119.662 104.968 125.772 1.00 296.28 ? 584 PRO A CD  1 
ATOM   3300  N  N   . ALA A 1 586 ? 122.759 106.417 122.404 1.00 286.97 ? 585 ALA A N   1 
ATOM   3301  C  CA  . ALA A 1 586 ? 122.832 107.284 121.226 1.00 340.64 ? 585 ALA A CA  1 
ATOM   3302  C  C   . ALA A 1 586 ? 122.198 106.642 119.977 1.00 310.37 ? 585 ALA A C   1 
ATOM   3303  O  O   . ALA A 1 586 ? 121.762 107.362 119.066 1.00 218.33 ? 585 ALA A O   1 
ATOM   3304  C  CB  . ALA A 1 586 ? 124.277 107.670 120.984 1.00 411.65 ? 585 ALA A CB  1 
ATOM   3305  N  N   . SER A 1 587 ? 122.158 105.293 119.952 1.00 342.78 ? 586 SER A N   1 
ATOM   3306  C  CA  . SER A 1 587 ? 121.497 104.481 118.935 1.00 304.58 ? 586 SER A CA  1 
ATOM   3307  C  C   . SER A 1 587 ? 119.971 104.527 118.998 1.00 255.26 ? 586 SER A C   1 
ATOM   3308  O  O   . SER A 1 587 ? 119.354 104.149 118.011 1.00 285.90 ? 586 SER A O   1 
ATOM   3309  C  CB  . SER A 1 587 ? 121.950 103.039 119.065 1.00 311.06 ? 586 SER A CB  1 
ATOM   3310  O  OG  . SER A 1 587 ? 121.646 102.518 120.356 1.00 238.31 ? 586 SER A OG  1 
ATOM   3311  N  N   . ALA A 1 588 ? 119.382 104.963 120.129 1.00 255.83 ? 587 ALA A N   1 
ATOM   3312  C  CA  . ALA A 1 588 ? 117.976 104.748 120.447 1.00 214.94 ? 587 ALA A CA  1 
ATOM   3313  C  C   . ALA A 1 588 ? 117.237 106.045 120.795 1.00 198.35 ? 587 ALA A C   1 
ATOM   3314  O  O   . ALA A 1 588 ? 116.202 105.986 121.462 1.00 215.83 ? 587 ALA A O   1 
ATOM   3315  C  CB  . ALA A 1 588 ? 117.902 103.742 121.562 1.00 223.22 ? 587 ALA A CB  1 
ATOM   3316  N  N   . SER A 1 589 ? 117.751 107.199 120.329 1.00 207.15 ? 588 SER A N   1 
ATOM   3317  C  CA  . SER A 1 589 ? 117.251 108.512 120.715 1.00 198.38 ? 588 SER A CA  1 
ATOM   3318  C  C   . SER A 1 589 ? 115.758 108.650 120.402 1.00 140.00 ? 588 SER A C   1 
ATOM   3319  O  O   . SER A 1 589 ? 115.276 108.181 119.362 1.00 130.05 ? 588 SER A O   1 
ATOM   3320  C  CB  . SER A 1 589 ? 118.065 109.616 120.060 1.00 275.09 ? 588 SER A CB  1 
ATOM   3321  O  OG  . SER A 1 589 ? 118.095 109.476 118.645 1.00 323.49 ? 588 SER A OG  1 
ATOM   3322  N  N   . LEU A 1 590 ? 115.040 109.312 121.321 1.00 136.74 ? 589 LEU A N   1 
ATOM   3323  C  CA  . LEU A 1 590 ? 113.618 109.532 121.170 1.00 163.61 ? 589 LEU A CA  1 
ATOM   3324  C  C   . LEU A 1 590 ? 113.308 110.509 120.043 1.00 176.27 ? 589 LEU A C   1 
ATOM   3325  O  O   . LEU A 1 590 ? 114.036 111.487 119.819 1.00 162.09 ? 589 LEU A O   1 
ATOM   3326  C  CB  . LEU A 1 590 ? 113.022 110.162 122.423 1.00 166.19 ? 589 LEU A CB  1 
ATOM   3327  C  CG  . LEU A 1 590 ? 112.760 109.263 123.616 1.00 136.66 ? 589 LEU A CG  1 
ATOM   3328  C  CD1 . LEU A 1 590 ? 112.111 110.112 124.699 1.00 163.88 ? 589 LEU A CD1 1 
ATOM   3329  C  CD2 . LEU A 1 590 ? 111.873 108.113 123.256 1.00 107.32 ? 589 LEU A CD2 1 
ATOM   3330  N  N   . PRO A 1 591 ? 112.167 110.277 119.347 1.00 143.34 ? 590 PRO A N   1 
ATOM   3331  C  CA  . PRO A 1 591 ? 111.698 111.227 118.351 1.00 192.11 ? 590 PRO A CA  1 
ATOM   3332  C  C   . PRO A 1 591 ? 111.078 112.468 118.997 1.00 165.83 ? 590 PRO A C   1 
ATOM   3333  O  O   . PRO A 1 591 ? 110.894 112.536 120.203 1.00 189.76 ? 590 PRO A O   1 
ATOM   3334  C  CB  . PRO A 1 591 ? 110.680 110.354 117.607 1.00 154.23 ? 590 PRO A CB  1 
ATOM   3335  C  CG  . PRO A 1 591 ? 110.059 109.568 118.711 1.00 110.40 ? 590 PRO A CG  1 
ATOM   3336  C  CD  . PRO A 1 591 ? 111.264 109.112 119.483 1.00 101.90 ? 590 PRO A CD  1 
ATOM   3337  N  N   . ALA A 1 592 ? 110.750 113.454 118.166 1.00 154.47 ? 591 ALA A N   1 
ATOM   3338  C  CA  . ALA A 1 592 ? 109.951 114.582 118.598 1.00 207.93 ? 591 ALA A CA  1 
ATOM   3339  C  C   . ALA A 1 592 ? 108.497 114.164 118.852 1.00 155.61 ? 591 ALA A C   1 
ATOM   3340  O  O   . ALA A 1 592 ? 107.835 114.762 119.707 1.00 170.61 ? 591 ALA A O   1 
ATOM   3341  C  CB  . ALA A 1 592 ? 110.050 115.670 117.549 1.00 320.85 ? 591 ALA A CB  1 
ATOM   3342  N  N   . LYS A 1 593 ? 108.010 113.173 118.082 1.00 131.67 ? 592 LYS A N   1 
ATOM   3343  C  CA  . LYS A 1 593 ? 106.648 112.664 118.165 1.00 138.49 ? 592 LYS A CA  1 
ATOM   3344  C  C   . LYS A 1 593 ? 106.636 111.181 117.802 1.00 145.36 ? 592 LYS A C   1 
ATOM   3345  O  O   . LYS A 1 593 ? 107.486 110.715 117.034 1.00 149.94 ? 592 LYS A O   1 
ATOM   3346  C  CB  . LYS A 1 593 ? 105.680 113.336 117.180 1.00 170.57 ? 592 LYS A CB  1 
ATOM   3347  C  CG  . LYS A 1 593 ? 105.554 114.850 117.218 1.00 229.41 ? 592 LYS A CG  1 
ATOM   3348  C  CD  . LYS A 1 593 ? 104.294 115.302 116.484 1.00 298.24 ? 592 LYS A CD  1 
ATOM   3349  C  CE  . LYS A 1 593 ? 104.209 116.797 116.256 1.00 396.22 ? 592 LYS A CE  1 
ATOM   3350  N  NZ  . LYS A 1 593 ? 105.050 117.227 115.113 1.00 428.59 ? 592 LYS A NZ  1 
ATOM   3351  N  N   . ALA A 1 594 ? 105.647 110.462 118.350 1.00 142.47 ? 593 ALA A N   1 
ATOM   3352  C  CA  . ALA A 1 594 ? 105.480 109.029 118.137 1.00 134.36 ? 593 ALA A CA  1 
ATOM   3353  C  C   . ALA A 1 594 ? 103.994 108.666 118.146 1.00 132.09 ? 593 ALA A C   1 
ATOM   3354  O  O   . ALA A 1 594 ? 103.178 109.375 118.753 1.00 143.17 ? 593 ALA A O   1 
ATOM   3355  C  CB  . ALA A 1 594 ? 106.222 108.307 119.233 1.00 158.00 ? 593 ALA A CB  1 
ATOM   3356  N  N   . ASP A 1 595 ? 103.638 107.563 117.477 1.00 110.33 ? 594 ASP A N   1 
ATOM   3357  C  CA  . ASP A 1 595 ? 102.235 107.189 117.277 1.00 173.63 ? 594 ASP A CA  1 
ATOM   3358  C  C   . ASP A 1 595 ? 101.654 106.407 118.458 1.00 95.62  ? 594 ASP A C   1 
ATOM   3359  O  O   . ASP A 1 595 ? 102.143 105.322 118.701 1.00 112.55 ? 594 ASP A O   1 
ATOM   3360  C  CB  . ASP A 1 595 ? 102.061 106.303 116.035 1.00 266.76 ? 594 ASP A CB  1 
ATOM   3361  C  CG  . ASP A 1 595 ? 102.538 106.877 114.706 1.00 330.60 ? 594 ASP A CG  1 
ATOM   3362  O  OD1 . ASP A 1 595 ? 102.873 108.074 114.644 1.00 313.44 ? 594 ASP A OD1 1 
ATOM   3363  O  OD2 . ASP A 1 595 ? 102.566 106.105 113.725 1.00 403.32 ? 594 ASP A OD2 1 
ATOM   3364  N  N   . LEU A 1 596 ? 100.627 106.921 119.153 1.00 63.64  ? 595 LEU A N   1 
ATOM   3365  C  CA  . LEU A 1 596 ? 99.945  106.117 120.152 1.00 85.16  ? 595 LEU A CA  1 
ATOM   3366  C  C   . LEU A 1 596 ? 99.273  104.846 119.587 1.00 69.35  ? 595 LEU A C   1 
ATOM   3367  O  O   . LEU A 1 596 ? 98.252  104.886 118.966 1.00 151.85 ? 595 LEU A O   1 
ATOM   3368  C  CB  . LEU A 1 596 ? 98.933  107.017 120.844 1.00 105.15 ? 595 LEU A CB  1 
ATOM   3369  C  CG  . LEU A 1 596 ? 98.010  106.374 121.879 1.00 100.05 ? 595 LEU A CG  1 
ATOM   3370  C  CD1 . LEU A 1 596 ? 98.800  105.775 122.954 1.00 88.55  ? 595 LEU A CD1 1 
ATOM   3371  C  CD2 . LEU A 1 596 ? 97.137  107.437 122.527 1.00 158.13 ? 595 LEU A CD2 1 
ATOM   3372  N  N   . LEU A 1 597 ? 99.832  103.704 119.856 1.00 88.78  ? 596 LEU A N   1 
ATOM   3373  C  CA  . LEU A 1 597 ? 99.293  102.429 119.467 1.00 99.63  ? 596 LEU A CA  1 
ATOM   3374  C  C   . LEU A 1 597 ? 98.209  101.931 120.436 1.00 95.17  ? 596 LEU A C   1 
ATOM   3375  O  O   . LEU A 1 597 ? 97.305  101.209 120.002 1.00 127.26 ? 596 LEU A O   1 
ATOM   3376  C  CB  . LEU A 1 597 ? 100.452 101.440 119.414 1.00 104.48 ? 596 LEU A CB  1 
ATOM   3377  C  CG  . LEU A 1 597 ? 100.098 100.041 118.981 1.00 128.50 ? 596 LEU A CG  1 
ATOM   3378  C  CD1 . LEU A 1 597 ? 99.533  100.080 117.579 1.00 267.06 ? 596 LEU A CD1 1 
ATOM   3379  C  CD2 . LEU A 1 597 ? 101.336 99.224  118.990 1.00 195.19 ? 596 LEU A CD2 1 
ATOM   3380  N  N   . LEU A 1 598 ? 98.293  102.278 121.714 1.00 78.63  ? 597 LEU A N   1 
ATOM   3381  C  CA  . LEU A 1 598 ? 97.172  102.146 122.636 1.00 127.24 ? 597 LEU A CA  1 
ATOM   3382  C  C   . LEU A 1 598 ? 97.512  102.847 123.932 1.00 98.93  ? 597 LEU A C   1 
ATOM   3383  O  O   . LEU A 1 598 ? 98.670  103.035 124.240 1.00 74.18  ? 597 LEU A O   1 
ATOM   3384  C  CB  . LEU A 1 598 ? 96.793  100.690 122.981 1.00 149.91 ? 597 LEU A CB  1 
ATOM   3385  C  CG  . LEU A 1 598 ? 97.729  99.894  123.906 1.00 108.52 ? 597 LEU A CG  1 
ATOM   3386  C  CD1 . LEU A 1 598 ? 97.284  99.998  125.307 1.00 106.70 ? 597 LEU A CD1 1 
ATOM   3387  C  CD2 . LEU A 1 598 ? 97.780  98.450  123.603 1.00 100.05 ? 597 LEU A CD2 1 
ATOM   3388  N  N   . SER A 1 599 ? 96.479  103.187 124.707 1.00 101.11 ? 598 SER A N   1 
ATOM   3389  C  CA  . SER A 1 599 ? 96.667  103.598 126.087 1.00 92.95  ? 598 SER A CA  1 
ATOM   3390  C  C   . SER A 1 599 ? 95.862  102.674 126.984 1.00 85.11  ? 598 SER A C   1 
ATOM   3391  O  O   . SER A 1 599 ? 94.807  102.153 126.605 1.00 101.41 ? 598 SER A O   1 
ATOM   3392  C  CB  . SER A 1 599 ? 96.252  105.039 126.303 1.00 124.10 ? 598 SER A CB  1 
ATOM   3393  O  OG  . SER A 1 599 ? 96.212  105.373 127.687 1.00 95.29  ? 598 SER A OG  1 
ATOM   3394  N  N   . THR A 1 600 ? 96.369  102.523 128.203 1.00 83.38  ? 599 THR A N   1 
ATOM   3395  C  CA  . THR A 1 600 ? 95.680  101.876 129.312 1.00 99.49  ? 599 THR A CA  1 
ATOM   3396  C  C   . THR A 1 600 ? 94.373  102.579 129.675 1.00 105.82 ? 599 THR A C   1 
ATOM   3397  O  O   . THR A 1 600 ? 93.570  101.997 130.393 1.00 133.25 ? 599 THR A O   1 
ATOM   3398  C  CB  . THR A 1 600 ? 96.688  101.761 130.477 1.00 102.07 ? 599 THR A CB  1 
ATOM   3399  O  OG1 . THR A 1 600 ? 97.454  100.595 130.121 1.00 62.78  ? 599 THR A OG1 1 
ATOM   3400  C  CG2 . THR A 1 600 ? 96.119  101.767 131.894 1.00 111.24 ? 599 THR A CG2 1 
ATOM   3401  N  N   . GLN A 1 601 ? 94.152  103.815 129.212 1.00 109.49 ? 600 GLN A N   1 
ATOM   3402  C  CA  . GLN A 1 601 ? 92.964  104.547 129.591 1.00 171.05 ? 600 GLN A CA  1 
ATOM   3403  C  C   . GLN A 1 601 ? 92.114  104.959 128.378 1.00 216.42 ? 600 GLN A C   1 
ATOM   3404  O  O   . GLN A 1 601 ? 92.603  105.202 127.276 1.00 199.44 ? 600 GLN A O   1 
ATOM   3405  C  CB  . GLN A 1 601 ? 93.401  105.743 130.444 1.00 140.75 ? 600 GLN A CB  1 
ATOM   3406  C  CG  . GLN A 1 601 ? 93.766  105.345 131.866 1.00 161.11 ? 600 GLN A CG  1 
ATOM   3407  C  CD  . GLN A 1 601 ? 93.566  106.459 132.870 1.00 224.66 ? 600 GLN A CD  1 
ATOM   3408  O  OE1 . GLN A 1 601 ? 93.548  107.647 132.546 1.00 233.67 ? 600 GLN A OE1 1 
ATOM   3409  N  NE2 . GLN A 1 601 ? 93.416  106.071 134.125 1.00 284.28 ? 600 GLN A NE2 1 
ATOM   3410  N  N   . PRO A 1 602 ? 90.780  105.069 128.575 1.00 224.45 ? 601 PRO A N   1 
ATOM   3411  C  CA  . PRO A 1 602 ? 89.913  105.662 127.559 1.00 225.19 ? 601 PRO A CA  1 
ATOM   3412  C  C   . PRO A 1 602 ? 90.128  107.166 127.405 1.00 183.53 ? 601 PRO A C   1 
ATOM   3413  O  O   . PRO A 1 602 ? 90.758  107.818 128.236 1.00 238.02 ? 601 PRO A O   1 
ATOM   3414  C  CB  . PRO A 1 602 ? 88.508  105.371 128.119 1.00 293.64 ? 601 PRO A CB  1 
ATOM   3415  C  CG  . PRO A 1 602 ? 88.701  105.323 129.622 1.00 214.63 ? 601 PRO A CG  1 
ATOM   3416  C  CD  . PRO A 1 602 ? 90.039  104.652 129.785 1.00 185.20 ? 601 PRO A CD  1 
ATOM   3417  N  N   . GLY A 1 603 ? 89.577  107.714 126.330 1.00 212.72 ? 602 GLY A N   1 
ATOM   3418  C  CA  . GLY A 1 603 ? 89.617  109.149 126.092 1.00 284.81 ? 602 GLY A CA  1 
ATOM   3419  C  C   . GLY A 1 603 ? 90.896  109.606 125.390 1.00 278.33 ? 602 GLY A C   1 
ATOM   3420  O  O   . GLY A 1 603 ? 91.255  110.784 125.517 1.00 286.03 ? 602 GLY A O   1 
ATOM   3421  N  N   . ARG A 1 604 ? 91.549  108.679 124.649 1.00 191.73 ? 603 ARG A N   1 
ATOM   3422  C  CA  . ARG A 1 604 ? 92.778  108.948 123.914 1.00 166.50 ? 603 ARG A CA  1 
ATOM   3423  C  C   . ARG A 1 604 ? 92.629  108.738 122.414 1.00 161.35 ? 603 ARG A C   1 
ATOM   3424  O  O   . ARG A 1 604 ? 91.790  107.947 121.972 1.00 199.77 ? 603 ARG A O   1 
ATOM   3425  C  CB  . ARG A 1 604 ? 93.853  107.995 124.405 1.00 220.05 ? 603 ARG A CB  1 
ATOM   3426  C  CG  . ARG A 1 604 ? 94.462  108.442 125.714 1.00 253.73 ? 603 ARG A CG  1 
ATOM   3427  C  CD  . ARG A 1 604 ? 95.355  109.657 125.549 1.00 246.67 ? 603 ARG A CD  1 
ATOM   3428  N  NE  . ARG A 1 604 ? 95.967  109.909 126.833 1.00 226.91 ? 603 ARG A NE  1 
ATOM   3429  C  CZ  . ARG A 1 604 ? 96.853  110.855 127.083 1.00 216.67 ? 603 ARG A CZ  1 
ATOM   3430  N  NH1 . ARG A 1 604 ? 97.200  111.012 128.342 1.00 241.06 ? 603 ARG A NH1 1 
ATOM   3431  N  NH2 . ARG A 1 604 ? 97.368  111.615 126.129 1.00 172.97 ? 603 ARG A NH2 1 
ATOM   3432  N  N   . GLU A 1 605 ? 93.457  109.459 121.640 1.00 174.26 ? 604 GLU A N   1 
ATOM   3433  C  CA  . GLU A 1 605 ? 93.318  109.503 120.187 1.00 251.32 ? 604 GLU A CA  1 
ATOM   3434  C  C   . GLU A 1 605 ? 94.188  108.408 119.554 1.00 195.90 ? 604 GLU A C   1 
ATOM   3435  O  O   . GLU A 1 605 ? 95.200  108.689 118.906 1.00 89.90  ? 604 GLU A O   1 
ATOM   3436  C  CB  . GLU A 1 605 ? 93.657  110.905 119.669 1.00 312.83 ? 604 GLU A CB  1 
ATOM   3437  C  CG  . GLU A 1 605 ? 92.666  111.994 120.054 1.00 356.37 ? 604 GLU A CG  1 
ATOM   3438  C  CD  . GLU A 1 605 ? 93.129  113.413 119.757 1.00 389.48 ? 604 GLU A CD  1 
ATOM   3439  O  OE1 . GLU A 1 605 ? 93.654  113.636 118.646 1.00 428.16 ? 604 GLU A OE1 1 
ATOM   3440  O  OE2 . GLU A 1 605 ? 92.962  114.300 120.632 1.00 405.00 ? 604 GLU A OE2 1 
ATOM   3441  N  N   . GLU A 1 606 ? 93.773  107.144 119.731 1.00 188.19 ? 605 GLU A N   1 
ATOM   3442  C  CA  . GLU A 1 606 ? 94.593  105.993 119.338 1.00 179.03 ? 605 GLU A CA  1 
ATOM   3443  C  C   . GLU A 1 606 ? 94.824  106.004 117.818 1.00 159.76 ? 605 GLU A C   1 
ATOM   3444  O  O   . GLU A 1 606 ? 93.907  106.225 117.038 1.00 216.49 ? 605 GLU A O   1 
ATOM   3445  C  CB  . GLU A 1 606 ? 94.014  104.659 119.835 1.00 173.99 ? 605 GLU A CB  1 
ATOM   3446  C  CG  . GLU A 1 606 ? 93.713  104.705 121.325 1.00 227.70 ? 605 GLU A CG  1 
ATOM   3447  C  CD  . GLU A 1 606 ? 93.624  103.421 122.132 1.00 283.73 ? 605 GLU A CD  1 
ATOM   3448  O  OE1 . GLU A 1 606 ? 93.110  102.404 121.612 1.00 398.54 ? 605 GLU A OE1 1 
ATOM   3449  O  OE2 . GLU A 1 606 ? 94.056  103.446 123.310 1.00 246.92 ? 605 GLU A OE2 1 
ATOM   3450  N  N   . GLY A 1 607 ? 96.077  105.767 117.411 1.00 192.57 ? 606 GLY A N   1 
ATOM   3451  C  CA  . GLY A 1 607 ? 96.548  105.973 116.049 1.00 202.47 ? 606 GLY A CA  1 
ATOM   3452  C  C   . GLY A 1 607 ? 97.280  107.308 115.837 1.00 186.23 ? 606 GLY A C   1 
ATOM   3453  O  O   . GLY A 1 607 ? 98.151  107.360 114.953 1.00 181.35 ? 606 GLY A O   1 
ATOM   3454  N  N   . SER A 1 608 ? 96.944  108.362 116.627 1.00 112.17 ? 607 SER A N   1 
ATOM   3455  C  CA  . SER A 1 608 ? 97.466  109.704 116.356 1.00 169.62 ? 607 SER A CA  1 
ATOM   3456  C  C   . SER A 1 608 ? 98.903  109.879 116.851 1.00 198.20 ? 607 SER A C   1 
ATOM   3457  O  O   . SER A 1 608 ? 99.313  109.225 117.809 1.00 265.26 ? 607 SER A O   1 
ATOM   3458  C  CB  . SER A 1 608 ? 96.608  110.767 116.963 1.00 184.90 ? 607 SER A CB  1 
ATOM   3459  O  OG  . SER A 1 608 ? 96.706  110.729 118.379 1.00 174.97 ? 607 SER A OG  1 
ATOM   3460  N  N   . PRO A 1 609 ? 99.726  110.760 116.230 1.00 184.48 ? 608 PRO A N   1 
ATOM   3461  C  CA  . PRO A 1 609 ? 101.019 111.147 116.805 1.00 244.59 ? 608 PRO A CA  1 
ATOM   3462  C  C   . PRO A 1 609 ? 100.877 112.087 118.007 1.00 242.54 ? 608 PRO A C   1 
ATOM   3463  O  O   . PRO A 1 609 ? 100.028 112.979 118.000 1.00 230.81 ? 608 PRO A O   1 
ATOM   3464  C  CB  . PRO A 1 609 ? 101.760 111.812 115.634 1.00 211.46 ? 608 PRO A CB  1 
ATOM   3465  C  CG  . PRO A 1 609 ? 100.663 112.333 114.762 1.00 230.47 ? 608 PRO A CG  1 
ATOM   3466  C  CD  . PRO A 1 609 ? 99.482  111.400 114.942 1.00 184.77 ? 608 PRO A CD  1 
ATOM   3467  N  N   . LEU A 1 610 ? 101.734 111.862 119.025 1.00 189.21 ? 609 LEU A N   1 
ATOM   3468  C  CA  . LEU A 1 610 ? 101.789 112.640 120.257 1.00 169.86 ? 609 LEU A CA  1 
ATOM   3469  C  C   . LEU A 1 610 ? 103.098 113.416 120.355 1.00 173.42 ? 609 LEU A C   1 
ATOM   3470  O  O   . LEU A 1 610 ? 104.118 112.887 119.908 1.00 107.49 ? 609 LEU A O   1 
ATOM   3471  C  CB  . LEU A 1 610 ? 101.719 111.646 121.413 1.00 145.30 ? 609 LEU A CB  1 
ATOM   3472  C  CG  . LEU A 1 610 ? 100.371 110.997 121.666 1.00 176.62 ? 609 LEU A CG  1 
ATOM   3473  C  CD1 . LEU A 1 610 ? 100.520 109.894 122.671 1.00 152.26 ? 609 LEU A CD1 1 
ATOM   3474  C  CD2 . LEU A 1 610 ? 99.388  112.014 122.221 1.00 258.08 ? 609 LEU A CD2 1 
ATOM   3475  N  N   . GLU A 1 611 ? 103.059 114.627 120.961 1.00 182.37 ? 610 GLU A N   1 
ATOM   3476  C  CA  . GLU A 1 611 ? 104.267 115.401 121.263 1.00 205.51 ? 610 GLU A CA  1 
ATOM   3477  C  C   . GLU A 1 611 ? 104.854 114.938 122.596 1.00 175.17 ? 610 GLU A C   1 
ATOM   3478  O  O   . GLU A 1 611 ? 104.312 115.219 123.646 1.00 156.64 ? 610 GLU A O   1 
ATOM   3479  C  CB  . GLU A 1 611 ? 104.000 116.910 121.353 1.00 262.64 ? 610 GLU A CB  1 
ATOM   3480  C  CG  . GLU A 1 611 ? 103.560 117.529 120.032 1.00 406.04 ? 610 GLU A CG  1 
ATOM   3481  C  CD  . GLU A 1 611 ? 102.120 117.281 119.594 1.00 521.56 ? 610 GLU A CD  1 
ATOM   3482  O  OE1 . GLU A 1 611 ? 101.296 116.846 120.432 1.00 544.21 ? 610 GLU A OE1 1 
ATOM   3483  O  OE2 . GLU A 1 611 ? 101.823 117.515 118.410 1.00 590.86 ? 610 GLU A OE2 1 
ATOM   3484  N  N   . LEU A 1 612 ? 105.976 114.238 122.578 1.00 143.09 ? 611 LEU A N   1 
ATOM   3485  C  CA  . LEU A 1 612 ? 106.533 113.704 123.801 1.00 109.96 ? 611 LEU A CA  1 
ATOM   3486  C  C   . LEU A 1 612 ? 106.947 114.802 124.779 1.00 116.05 ? 611 LEU A C   1 
ATOM   3487  O  O   . LEU A 1 612 ? 106.732 114.645 125.972 1.00 158.88 ? 611 LEU A O   1 
ATOM   3488  C  CB  . LEU A 1 612 ? 107.751 112.848 123.416 1.00 116.43 ? 611 LEU A CB  1 
ATOM   3489  C  CG  . LEU A 1 612 ? 107.447 111.544 122.679 1.00 91.04  ? 611 LEU A CG  1 
ATOM   3490  C  CD1 . LEU A 1 612 ? 108.685 110.647 122.688 1.00 91.34  ? 611 LEU A CD1 1 
ATOM   3491  C  CD2 . LEU A 1 612 ? 106.213 110.827 123.267 1.00 82.23  ? 611 LEU A CD2 1 
ATOM   3492  N  N   . GLU A 1 613 ? 107.550 115.903 124.336 1.00 105.45 ? 612 GLU A N   1 
ATOM   3493  C  CA  . GLU A 1 613 ? 107.871 116.980 125.276 1.00 111.09 ? 612 GLU A CA  1 
ATOM   3494  C  C   . GLU A 1 613 ? 106.626 117.660 125.927 1.00 96.46  ? 612 GLU A C   1 
ATOM   3495  O  O   . GLU A 1 613 ? 106.817 118.451 126.852 1.00 208.66 ? 612 GLU A O   1 
ATOM   3496  C  CB  . GLU A 1 613 ? 108.795 117.966 124.549 1.00 197.28 ? 612 GLU A CB  1 
ATOM   3497  C  CG  . GLU A 1 613 ? 109.352 119.109 125.397 1.00 225.09 ? 612 GLU A CG  1 
ATOM   3498  C  CD  . GLU A 1 613 ? 110.281 120.048 124.649 1.00 302.29 ? 612 GLU A CD  1 
ATOM   3499  O  OE1 . GLU A 1 613 ? 111.428 119.645 124.361 1.00 366.56 ? 612 GLU A OE1 1 
ATOM   3500  O  OE2 . GLU A 1 613 ? 109.843 121.181 124.350 1.00 289.23 ? 612 GLU A OE2 1 
ATOM   3501  N  N   . ARG A 1 614 ? 105.370 117.419 125.498 1.00 108.54 ? 613 ARG A N   1 
ATOM   3502  C  CA  . ARG A 1 614 ? 104.171 118.123 125.968 1.00 124.45 ? 613 ARG A CA  1 
ATOM   3503  C  C   . ARG A 1 614 ? 103.004 117.182 126.274 1.00 129.29 ? 613 ARG A C   1 
ATOM   3504  O  O   . ARG A 1 614 ? 101.864 117.617 126.420 1.00 185.11 ? 613 ARG A O   1 
ATOM   3505  C  CB  . ARG A 1 614 ? 103.754 119.150 124.893 1.00 159.27 ? 613 ARG A CB  1 
ATOM   3506  C  CG  . ARG A 1 614 ? 104.436 120.499 125.080 1.00 188.87 ? 613 ARG A CG  1 
ATOM   3507  C  CD  . ARG A 1 614 ? 104.305 121.458 123.917 1.00 227.55 ? 613 ARG A CD  1 
ATOM   3508  N  NE  . ARG A 1 614 ? 105.239 121.129 122.834 1.00 318.75 ? 613 ARG A NE  1 
ATOM   3509  C  CZ  . ARG A 1 614 ? 106.577 121.251 122.859 1.00 394.06 ? 613 ARG A CZ  1 
ATOM   3510  N  NH1 . ARG A 1 614 ? 107.283 120.827 121.822 1.00 441.54 ? 613 ARG A NH1 1 
ATOM   3511  N  NH2 . ARG A 1 614 ? 107.221 121.774 123.897 1.00 348.31 ? 613 ARG A NH2 1 
ATOM   3512  N  N   . LEU A 1 615 ? 103.297 115.883 126.370 1.00 131.45 ? 614 LEU A N   1 
ATOM   3513  C  CA  . LEU A 1 615 ? 102.392 114.789 126.712 1.00 140.00 ? 614 LEU A CA  1 
ATOM   3514  C  C   . LEU A 1 615 ? 101.892 114.874 128.159 1.00 140.21 ? 614 LEU A C   1 
ATOM   3515  O  O   . LEU A 1 615 ? 102.573 115.475 129.004 1.00 180.72 ? 614 LEU A O   1 
ATOM   3516  C  CB  . LEU A 1 615 ? 103.253 113.545 126.496 1.00 102.29 ? 614 LEU A CB  1 
ATOM   3517  C  CG  . LEU A 1 615 ? 102.588 112.217 126.723 1.00 133.28 ? 614 LEU A CG  1 
ATOM   3518  C  CD1 . LEU A 1 615 ? 101.416 112.071 125.745 1.00 234.41 ? 614 LEU A CD1 1 
ATOM   3519  C  CD2 . LEU A 1 615 ? 103.635 111.154 126.526 1.00 96.74  ? 614 LEU A CD2 1 
ATOM   3520  N  N   . LYS A 1 616 ? 100.718 114.276 128.461 1.00 97.54  ? 615 LYS A N   1 
ATOM   3521  C  CA  . LYS A 1 616 ? 100.190 114.349 129.829 1.00 137.62 ? 615 LYS A CA  1 
ATOM   3522  C  C   . LYS A 1 616 ? 99.620  112.998 130.270 1.00 129.94 ? 615 LYS A C   1 
ATOM   3523  O  O   . LYS A 1 616 ? 98.507  112.676 129.899 1.00 177.46 ? 615 LYS A O   1 
ATOM   3524  C  CB  . LYS A 1 616 ? 99.110  115.436 129.996 1.00 159.09 ? 615 LYS A CB  1 
ATOM   3525  C  CG  . LYS A 1 616 ? 99.563  116.877 129.748 1.00 183.49 ? 615 LYS A CG  1 
ATOM   3526  C  CD  . LYS A 1 616 ? 98.765  117.973 130.460 1.00 279.87 ? 615 LYS A CD  1 
ATOM   3527  C  CE  . LYS A 1 616 ? 97.257  117.887 130.332 1.00 348.64 ? 615 LYS A CE  1 
ATOM   3528  N  NZ  . LYS A 1 616 ? 96.583  118.853 131.236 1.00 347.76 ? 615 LYS A NZ  1 
ATOM   3529  N  N   . LEU A 1 617 ? 100.363 112.217 131.068 1.00 96.75  ? 616 LEU A N   1 
ATOM   3530  C  CA  . LEU A 1 617 ? 99.905  110.955 131.620 1.00 63.89  ? 616 LEU A CA  1 
ATOM   3531  C  C   . LEU A 1 617 ? 99.004  111.231 132.838 1.00 86.56  ? 616 LEU A C   1 
ATOM   3532  O  O   . LEU A 1 617 ? 99.279  112.075 133.699 1.00 84.95  ? 616 LEU A O   1 
ATOM   3533  C  CB  . LEU A 1 617 ? 101.075 110.127 132.132 1.00 56.19  ? 616 LEU A CB  1 
ATOM   3534  C  CG  . LEU A 1 617 ? 102.159 109.582 131.202 1.00 83.54  ? 616 LEU A CG  1 
ATOM   3535  C  CD1 . LEU A 1 617 ? 101.532 108.744 130.120 1.00 105.12 ? 616 LEU A CD1 1 
ATOM   3536  C  CD2 . LEU A 1 617 ? 103.083 110.707 130.650 1.00 99.42  ? 616 LEU A CD2 1 
ATOM   3537  N  N   . GLU A 1 618 ? 97.902  110.490 132.947 1.00 93.20  ? 617 GLU A N   1 
ATOM   3538  C  CA  . GLU A 1 618 ? 97.106  110.463 134.169 1.00 81.53  ? 617 GLU A CA  1 
ATOM   3539  C  C   . GLU A 1 618 ? 97.751  109.539 135.176 1.00 69.87  ? 617 GLU A C   1 
ATOM   3540  O  O   . GLU A 1 618 ? 98.585  108.744 134.806 1.00 101.92 ? 617 GLU A O   1 
ATOM   3541  C  CB  . GLU A 1 618 ? 95.674  110.037 133.842 1.00 124.32 ? 617 GLU A CB  1 
ATOM   3542  C  CG  . GLU A 1 618 ? 94.913  111.111 133.049 1.00 239.78 ? 617 GLU A CG  1 
ATOM   3543  C  CD  . GLU A 1 618 ? 94.739  112.477 133.712 1.00 300.81 ? 617 GLU A CD  1 
ATOM   3544  O  OE1 . GLU A 1 618 ? 94.296  112.506 134.884 1.00 324.18 ? 617 GLU A OE1 1 
ATOM   3545  O  OE2 . GLU A 1 618 ? 95.042  113.517 133.060 1.00 292.51 ? 617 GLU A OE2 1 
ATOM   3546  N  N   . PRO A 1 619 ? 97.402  109.558 136.480 1.00 80.34  ? 618 PRO A N   1 
ATOM   3547  C  CA  . PRO A 1 619 ? 97.765  108.497 137.435 1.00 79.01  ? 618 PRO A CA  1 
ATOM   3548  C  C   . PRO A 1 619 ? 97.420  107.090 136.891 1.00 97.67  ? 618 PRO A C   1 
ATOM   3549  O  O   . PRO A 1 619 ? 96.303  106.763 136.463 1.00 114.93 ? 618 PRO A O   1 
ATOM   3550  C  CB  . PRO A 1 619 ? 96.883  108.739 138.627 1.00 92.58  ? 618 PRO A CB  1 
ATOM   3551  C  CG  . PRO A 1 619 ? 96.648  110.222 138.563 1.00 132.12 ? 618 PRO A CG  1 
ATOM   3552  C  CD  . PRO A 1 619 ? 96.602  110.597 137.095 1.00 106.32 ? 618 PRO A CD  1 
ATOM   3553  N  N   . HIS A 1 620 ? 98.428  106.247 136.833 1.00 82.13  ? 619 HIS A N   1 
ATOM   3554  C  CA  . HIS A 1 620 ? 98.285  104.910 136.353 1.00 75.53  ? 619 HIS A CA  1 
ATOM   3555  C  C   . HIS A 1 620 ? 98.082  104.803 134.836 1.00 66.98  ? 619 HIS A C   1 
ATOM   3556  O  O   . HIS A 1 620 ? 97.899  103.710 134.334 1.00 107.30 ? 619 HIS A O   1 
ATOM   3557  C  CB  . HIS A 1 620 ? 97.255  104.317 137.311 1.00 100.33 ? 619 HIS A CB  1 
ATOM   3558  C  CG  . HIS A 1 620 ? 97.697  104.327 138.760 1.00 104.09 ? 619 HIS A CG  1 
ATOM   3559  N  ND1 . HIS A 1 620 ? 96.800  104.788 139.685 1.00 150.63 ? 619 HIS A ND1 1 
ATOM   3560  C  CD2 . HIS A 1 620 ? 98.775  103.937 139.478 1.00 85.84  ? 619 HIS A CD2 1 
ATOM   3561  C  CE1 . HIS A 1 620 ? 97.337  104.691 140.900 1.00 171.65 ? 619 HIS A CE1 1 
ATOM   3562  N  NE2 . HIS A 1 620 ? 98.539  104.185 140.788 1.00 81.49  ? 619 HIS A NE2 1 
ATOM   3563  N  N   . GLU A 1 621 ? 98.144  105.861 134.073 1.00 68.42  ? 620 GLU A N   1 
ATOM   3564  C  CA  . GLU A 1 621 ? 98.052  105.709 132.630 1.00 94.17  ? 620 GLU A CA  1 
ATOM   3565  C  C   . GLU A 1 621 ? 99.336  105.168 132.050 1.00 69.58  ? 620 GLU A C   1 
ATOM   3566  O  O   . GLU A 1 621 ? 100.311 105.902 132.007 1.00 120.30 ? 620 GLU A O   1 
ATOM   3567  C  CB  . GLU A 1 621 ? 97.836  107.057 131.916 1.00 129.69 ? 620 GLU A CB  1 
ATOM   3568  C  CG  . GLU A 1 621 ? 97.745  106.984 130.380 1.00 144.44 ? 620 GLU A CG  1 
ATOM   3569  C  CD  . GLU A 1 621 ? 96.871  108.055 129.736 1.00 231.67 ? 620 GLU A CD  1 
ATOM   3570  O  OE1 . GLU A 1 621 ? 96.733  109.163 130.318 1.00 239.78 ? 620 GLU A OE1 1 
ATOM   3571  O  OE2 . GLU A 1 621 ? 96.311  107.805 128.662 1.00 260.74 ? 620 GLU A OE2 1 
ATOM   3572  N  N   . GLY A 1 622 ? 99.338  103.945 131.582 1.00 57.30  ? 621 GLY A N   1 
ATOM   3573  C  CA  . GLY A 1 622 ? 100.381 103.565 130.641 1.00 88.74  ? 621 GLY A CA  1 
ATOM   3574  C  C   . GLY A 1 622 ? 100.113 103.781 129.140 1.00 65.67  ? 621 GLY A C   1 
ATOM   3575  O  O   . GLY A 1 622 ? 99.041  103.581 128.684 1.00 74.42  ? 621 GLY A O   1 
ATOM   3576  N  N   . LEU A 1 623 ? 101.131 104.105 128.381 1.00 63.20  ? 622 LEU A N   1 
ATOM   3577  C  CA  . LEU A 1 623 ? 101.082 104.270 126.943 1.00 68.65  ? 622 LEU A CA  1 
ATOM   3578  C  C   . LEU A 1 623 ? 102.001 103.328 126.211 1.00 66.42  ? 622 LEU A C   1 
ATOM   3579  O  O   . LEU A 1 623 ? 103.100 103.072 126.712 1.00 70.97  ? 622 LEU A O   1 
ATOM   3580  C  CB  . LEU A 1 623 ? 101.690 105.621 126.587 1.00 66.75  ? 622 LEU A CB  1 
ATOM   3581  C  CG  . LEU A 1 623 ? 100.950 106.781 127.217 1.00 87.77  ? 622 LEU A CG  1 
ATOM   3582  C  CD1 . LEU A 1 623 ? 101.727 108.016 126.768 1.00 80.21  ? 622 LEU A CD1 1 
ATOM   3583  C  CD2 . LEU A 1 623 ? 99.413  106.771 126.877 1.00 95.47  ? 622 LEU A CD2 1 
ATOM   3584  N  N   . LEU A 1 624 ? 101.546 102.884 125.032 1.00 62.93  ? 623 LEU A N   1 
ATOM   3585  C  CA  . LEU A 1 624 ? 102.388 102.130 124.131 1.00 63.93  ? 623 LEU A CA  1 
ATOM   3586  C  C   . LEU A 1 624 ? 102.568 102.965 122.891 1.00 50.59  ? 623 LEU A C   1 
ATOM   3587  O  O   . LEU A 1 624 ? 101.649 103.111 122.155 1.00 102.03 ? 623 LEU A O   1 
ATOM   3588  C  CB  . LEU A 1 624 ? 101.760 100.756 123.886 1.00 54.42  ? 623 LEU A CB  1 
ATOM   3589  C  CG  . LEU A 1 624 ? 102.544 99.838  122.946 1.00 66.58  ? 623 LEU A CG  1 
ATOM   3590  C  CD1 . LEU A 1 624 ? 103.987 99.586  123.342 1.00 73.17  ? 623 LEU A CD1 1 
ATOM   3591  C  CD2 . LEU A 1 624 ? 101.846 98.500  122.877 1.00 65.55  ? 623 LEU A CD2 1 
ATOM   3592  N  N   . LEU A 1 625 ? 103.752 103.522 122.675 1.00 85.87  ? 624 LEU A N   1 
ATOM   3593  C  CA  . LEU A 1 625 ? 104.027 104.410 121.550 1.00 82.64  ? 624 LEU A CA  1 
ATOM   3594  C  C   . LEU A 1 625 ? 104.870 103.593 120.592 1.00 102.52 ? 624 LEU A C   1 
ATOM   3595  O  O   . LEU A 1 625 ? 105.748 102.835 120.985 1.00 109.67 ? 624 LEU A O   1 
ATOM   3596  C  CB  . LEU A 1 625 ? 104.720 105.713 121.985 1.00 75.57  ? 624 LEU A CB  1 
ATOM   3597  C  CG  . LEU A 1 625 ? 103.995 106.417 123.151 1.00 96.99  ? 624 LEU A CG  1 
ATOM   3598  C  CD1 . LEU A 1 625 ? 104.600 107.755 123.549 1.00 112.57 ? 624 LEU A CD1 1 
ATOM   3599  C  CD2 . LEU A 1 625 ? 102.556 106.650 122.797 1.00 85.30  ? 624 LEU A CD2 1 
ATOM   3600  N  N   . ARG A 1 626 ? 104.564 103.804 119.318 1.00 118.53 ? 625 ARG A N   1 
ATOM   3601  C  CA  . ARG A 1 626 ? 105.202 103.174 118.182 1.00 118.85 ? 625 ARG A CA  1 
ATOM   3602  C  C   . ARG A 1 626 ? 105.927 104.310 117.442 1.00 96.34  ? 625 ARG A C   1 
ATOM   3603  O  O   . ARG A 1 626 ? 105.376 105.363 117.210 1.00 111.31 ? 625 ARG A O   1 
ATOM   3604  C  CB  . ARG A 1 626 ? 104.062 102.468 117.449 1.00 146.02 ? 625 ARG A CB  1 
ATOM   3605  C  CG  . ARG A 1 626 ? 104.341 101.957 116.057 1.00 152.91 ? 625 ARG A CG  1 
ATOM   3606  C  CD  . ARG A 1 626 ? 103.081 101.505 115.298 1.00 174.06 ? 625 ARG A CD  1 
ATOM   3607  N  NE  . ARG A 1 626 ? 103.529 100.670 114.180 1.00 256.41 ? 625 ARG A NE  1 
ATOM   3608  C  CZ  . ARG A 1 626 ? 103.540 99.322  114.108 1.00 338.15 ? 625 ARG A CZ  1 
ATOM   3609  N  NH1 . ARG A 1 626 ? 104.261 98.738  113.161 1.00 436.91 ? 625 ARG A NH1 1 
ATOM   3610  N  NH2 . ARG A 1 626 ? 102.879 98.534  114.955 1.00 219.15 ? 625 ARG A NH2 1 
ATOM   3611  N  N   . PHE A 1 627 ? 107.160 104.114 117.015 1.00 97.13  ? 626 PHE A N   1 
ATOM   3612  C  CA  . PHE A 1 627 ? 107.795 105.072 116.131 1.00 112.40 ? 626 PHE A CA  1 
ATOM   3613  C  C   . PHE A 1 627 ? 108.774 104.413 115.155 1.00 166.75 ? 626 PHE A C   1 
ATOM   3614  O  O   . PHE A 1 627 ? 109.380 103.387 115.463 1.00 154.14 ? 626 PHE A O   1 
ATOM   3615  C  CB  . PHE A 1 627 ? 108.486 106.143 116.952 1.00 117.45 ? 626 PHE A CB  1 
ATOM   3616  C  CG  . PHE A 1 627 ? 109.570 105.768 117.934 1.00 119.08 ? 626 PHE A CG  1 
ATOM   3617  C  CD1 . PHE A 1 627 ? 110.881 105.485 117.537 1.00 134.48 ? 626 PHE A CD1 1 
ATOM   3618  C  CD2 . PHE A 1 627 ? 109.292 105.769 119.286 1.00 118.22 ? 626 PHE A CD2 1 
ATOM   3619  C  CE1 . PHE A 1 627 ? 111.872 105.156 118.461 1.00 99.33  ? 626 PHE A CE1 1 
ATOM   3620  C  CE2 . PHE A 1 627 ? 110.297 105.437 120.183 1.00 133.84 ? 626 PHE A CE2 1 
ATOM   3621  C  CZ  . PHE A 1 627 ? 111.581 105.138 119.776 1.00 99.04  ? 626 PHE A CZ  1 
ATOM   3622  N  N   . PRO A 1 628 ? 108.943 104.994 113.945 1.00 168.24 ? 627 PRO A N   1 
ATOM   3623  C  CA  . PRO A 1 628 ? 109.833 104.411 112.951 1.00 147.96 ? 627 PRO A CA  1 
ATOM   3624  C  C   . PRO A 1 628 ? 111.297 104.729 113.174 1.00 125.54 ? 627 PRO A C   1 
ATOM   3625  O  O   . PRO A 1 628 ? 111.627 105.685 113.902 1.00 152.67 ? 627 PRO A O   1 
ATOM   3626  C  CB  . PRO A 1 628 ? 109.353 105.098 111.668 1.00 249.98 ? 627 PRO A CB  1 
ATOM   3627  C  CG  . PRO A 1 628 ? 108.947 106.490 112.134 1.00 249.22 ? 627 PRO A CG  1 
ATOM   3628  C  CD  . PRO A 1 628 ? 108.281 106.225 113.466 1.00 214.14 ? 627 PRO A CD  1 
ATOM   3629  N  N   . TYR A 1 629 ? 112.139 103.903 112.520 1.00 123.93 ? 628 TYR A N   1 
ATOM   3630  C  CA  . TYR A 1 629 ? 113.593 103.906 112.680 1.00 139.49 ? 628 TYR A CA  1 
ATOM   3631  C  C   . TYR A 1 629 ? 114.249 105.214 112.214 1.00 153.39 ? 628 TYR A C   1 
ATOM   3632  O  O   . TYR A 1 629 ? 113.616 106.035 111.528 1.00 126.10 ? 628 TYR A O   1 
ATOM   3633  C  CB  . TYR A 1 629 ? 114.142 102.708 111.914 1.00 124.33 ? 628 TYR A CB  1 
ATOM   3634  C  CG  . TYR A 1 629 ? 115.648 102.493 111.922 1.00 144.21 ? 628 TYR A CG  1 
ATOM   3635  C  CD1 . TYR A 1 629 ? 116.328 102.141 113.086 1.00 240.81 ? 628 TYR A CD1 1 
ATOM   3636  C  CD2 . TYR A 1 629 ? 116.394 102.612 110.760 1.00 157.60 ? 628 TYR A CD2 1 
ATOM   3637  C  CE1 . TYR A 1 629 ? 117.702 101.932 113.095 1.00 256.84 ? 628 TYR A CE1 1 
ATOM   3638  C  CE2 . TYR A 1 629 ? 117.768 102.395 110.749 1.00 200.65 ? 628 TYR A CE2 1 
ATOM   3639  C  CZ  . TYR A 1 629 ? 118.432 102.061 111.924 1.00 195.80 ? 628 TYR A CZ  1 
ATOM   3640  O  OH  . TYR A 1 629 ? 119.781 101.838 111.975 1.00 175.78 ? 628 TYR A OH  1 
ATOM   3641  N  N   . ALA A 1 630 ? 115.523 105.399 112.623 1.00 147.82 ? 629 ALA A N   1 
ATOM   3642  C  CA  . ALA A 1 630 ? 116.363 106.438 112.050 1.00 208.52 ? 629 ALA A CA  1 
ATOM   3643  C  C   . ALA A 1 630 ? 117.766 105.901 111.736 1.00 225.55 ? 629 ALA A C   1 
ATOM   3644  O  O   . ALA A 1 630 ? 118.428 105.304 112.596 1.00 153.62 ? 629 ALA A O   1 
ATOM   3645  C  CB  . ALA A 1 630 ? 116.391 107.613 112.997 1.00 231.57 ? 629 ALA A CB  1 
ATOM   3646  N  N   . ALA A 1 631 ? 118.207 106.134 110.484 1.00 295.04 ? 630 ALA A N   1 
ATOM   3647  C  CA  . ALA A 1 631 ? 119.495 105.674 109.984 1.00 431.07 ? 630 ALA A CA  1 
ATOM   3648  C  C   . ALA A 1 631 ? 120.615 106.576 110.531 1.00 479.00 ? 630 ALA A C   1 
ATOM   3649  O  O   . ALA A 1 631 ? 121.033 107.523 109.821 1.00 488.22 ? 630 ALA A O   1 
ATOM   3650  C  CB  . ALA A 1 631 ? 119.474 105.634 108.468 1.00 478.23 ? 630 ALA A CB  1 
ATOM   3651  N  N   . GLY B 2 43  ? 108.780 103.221 52.316  1.00 283.33 ? 43  GLY B N   1 
ATOM   3652  C  CA  . GLY B 2 43  ? 110.128 103.405 52.891  1.00 318.66 ? 43  GLY B CA  1 
ATOM   3653  C  C   . GLY B 2 43  ? 110.141 103.191 54.405  1.00 327.70 ? 43  GLY B C   1 
ATOM   3654  O  O   . GLY B 2 43  ? 110.643 102.168 54.867  1.00 297.53 ? 43  GLY B O   1 
ATOM   3655  N  N   . VAL B 2 44  ? 109.579 104.154 55.162  1.00 322.00 ? 44  VAL B N   1 
ATOM   3656  C  CA  . VAL B 2 44  ? 109.650 104.162 56.626  1.00 280.16 ? 44  VAL B CA  1 
ATOM   3657  C  C   . VAL B 2 44  ? 108.269 103.955 57.248  1.00 240.05 ? 44  VAL B C   1 
ATOM   3658  O  O   . VAL B 2 44  ? 107.330 104.724 57.013  1.00 222.45 ? 44  VAL B O   1 
ATOM   3659  C  CB  . VAL B 2 44  ? 110.305 105.431 57.207  1.00 254.22 ? 44  VAL B CB  1 
ATOM   3660  C  CG1 . VAL B 2 44  ? 111.813 105.371 57.043  1.00 255.88 ? 44  VAL B CG1 1 
ATOM   3661  C  CG2 . VAL B 2 44  ? 109.743 106.709 56.617  1.00 248.78 ? 44  VAL B CG2 1 
ATOM   3662  N  N   . THR B 2 45  ? 108.186 102.888 58.064  1.00 231.24 ? 45  THR B N   1 
ATOM   3663  C  CA  . THR B 2 45  ? 107.021 102.559 58.871  1.00 288.06 ? 45  THR B CA  1 
ATOM   3664  C  C   . THR B 2 45  ? 107.432 101.584 59.981  1.00 258.99 ? 45  THR B C   1 
ATOM   3665  O  O   . THR B 2 45  ? 108.507 100.987 59.917  1.00 292.64 ? 45  THR B O   1 
ATOM   3666  C  CB  . THR B 2 45  ? 105.898 101.997 57.986  1.00 361.18 ? 45  THR B CB  1 
ATOM   3667  O  OG1 . THR B 2 45  ? 104.709 101.964 58.778  1.00 379.21 ? 45  THR B OG1 1 
ATOM   3668  C  CG2 . THR B 2 45  ? 106.206 100.628 57.408  1.00 381.04 ? 45  THR B CG2 1 
ATOM   3669  N  N   . LEU B 2 46  ? 106.564 101.415 60.990  1.00 202.61 ? 46  LEU B N   1 
ATOM   3670  C  CA  . LEU B 2 46  ? 106.726 100.364 61.982  1.00 205.73 ? 46  LEU B CA  1 
ATOM   3671  C  C   . LEU B 2 46  ? 106.351 98.995  61.393  1.00 220.42 ? 46  LEU B C   1 
ATOM   3672  O  O   . LEU B 2 46  ? 105.166 98.704  61.167  1.00 187.42 ? 46  LEU B O   1 
ATOM   3673  C  CB  . LEU B 2 46  ? 105.854 100.736 63.185  1.00 244.49 ? 46  LEU B CB  1 
ATOM   3674  C  CG  . LEU B 2 46  ? 106.232 102.031 63.910  1.00 233.48 ? 46  LEU B CG  1 
ATOM   3675  C  CD1 . LEU B 2 46  ? 105.362 102.185 65.157  1.00 245.28 ? 46  LEU B CD1 1 
ATOM   3676  C  CD2 . LEU B 2 46  ? 107.723 102.096 64.290  1.00 202.88 ? 46  LEU B CD2 1 
ATOM   3677  N  N   . GLN B 2 47  ? 107.367 98.139  61.147  1.00 201.75 ? 47  GLN B N   1 
ATOM   3678  C  CA  . GLN B 2 47  ? 107.150 96.871  60.450  1.00 225.46 ? 47  GLN B CA  1 
ATOM   3679  C  C   . GLN B 2 47  ? 106.513 95.795  61.342  1.00 253.46 ? 47  GLN B C   1 
ATOM   3680  O  O   . GLN B 2 47  ? 106.584 95.856  62.571  1.00 284.86 ? 47  GLN B O   1 
ATOM   3681  C  CB  . GLN B 2 47  ? 108.464 96.341  59.882  1.00 253.84 ? 47  GLN B CB  1 
ATOM   3682  C  CG  . GLN B 2 47  ? 108.933 97.124  58.666  1.00 307.44 ? 47  GLN B CG  1 
ATOM   3683  C  CD  . GLN B 2 47  ? 110.036 96.440  57.893  1.00 434.83 ? 47  GLN B CD  1 
ATOM   3684  O  OE1 . GLN B 2 47  ? 110.469 95.334  58.216  1.00 467.88 ? 47  GLN B OE1 1 
ATOM   3685  N  NE2 . GLN B 2 47  ? 110.502 97.101  56.844  1.00 513.08 ? 47  GLN B NE2 1 
ATOM   3686  N  N   . ARG B 2 48  ? 105.892 94.787  60.696  1.00 226.78 ? 48  ARG B N   1 
ATOM   3687  C  CA  . ARG B 2 48  ? 105.108 93.751  61.381  1.00 240.11 ? 48  ARG B CA  1 
ATOM   3688  C  C   . ARG B 2 48  ? 106.000 92.612  61.892  1.00 235.02 ? 48  ARG B C   1 
ATOM   3689  O  O   . ARG B 2 48  ? 106.124 91.573  61.239  1.00 184.62 ? 48  ARG B O   1 
ATOM   3690  C  CB  . ARG B 2 48  ? 103.975 93.293  60.454  1.00 201.25 ? 48  ARG B CB  1 
ATOM   3691  C  CG  . ARG B 2 48  ? 102.863 94.325  60.453  1.00 226.46 ? 48  ARG B CG  1 
ATOM   3692  C  CD  . ARG B 2 48  ? 101.635 94.084  59.608  1.00 232.52 ? 48  ARG B CD  1 
ATOM   3693  N  NE  . ARG B 2 48  ? 100.630 95.081  59.983  1.00 242.47 ? 48  ARG B NE  1 
ATOM   3694  C  CZ  . ARG B 2 48  ? 99.369  95.100  59.566  1.00 303.01 ? 48  ARG B CZ  1 
ATOM   3695  N  NH1 . ARG B 2 48  ? 98.531  96.023  60.014  1.00 230.13 ? 48  ARG B NH1 1 
ATOM   3696  N  NH2 . ARG B 2 48  ? 98.947  94.196  58.697  1.00 413.10 ? 48  ARG B NH2 1 
ATOM   3697  N  N   . ASN B 2 49  ? 106.599 92.832  63.083  1.00 224.31 ? 49  ASN B N   1 
ATOM   3698  C  CA  . ASN B 2 49  ? 107.580 91.928  63.673  1.00 248.03 ? 49  ASN B CA  1 
ATOM   3699  C  C   . ASN B 2 49  ? 106.965 90.874  64.610  1.00 218.06 ? 49  ASN B C   1 
ATOM   3700  O  O   . ASN B 2 49  ? 107.595 89.829  64.812  1.00 189.24 ? 49  ASN B O   1 
ATOM   3701  C  CB  . ASN B 2 49  ? 108.679 92.736  64.383  1.00 287.91 ? 49  ASN B CB  1 
ATOM   3702  C  CG  . ASN B 2 49  ? 109.627 93.431  63.421  1.00 334.73 ? 49  ASN B CG  1 
ATOM   3703  O  OD1 . ASN B 2 49  ? 109.837 94.640  63.495  1.00 293.04 ? 49  ASN B OD1 1 
ATOM   3704  N  ND2 . ASN B 2 49  ? 110.216 92.674  62.509  1.00 393.23 ? 49  ASN B ND2 1 
ATOM   3705  N  N   . ILE B 2 50  ? 105.764 91.115  65.175  1.00 203.82 ? 50  ILE B N   1 
ATOM   3706  C  CA  . ILE B 2 50  ? 105.278 90.341  66.321  1.00 178.45 ? 50  ILE B CA  1 
ATOM   3707  C  C   . ILE B 2 50  ? 104.582 89.062  65.859  1.00 198.43 ? 50  ILE B C   1 
ATOM   3708  O  O   . ILE B 2 50  ? 103.444 89.129  65.363  1.00 202.24 ? 50  ILE B O   1 
ATOM   3709  C  CB  . ILE B 2 50  ? 104.325 91.170  67.195  1.00 185.37 ? 50  ILE B CB  1 
ATOM   3710  C  CG1 . ILE B 2 50  ? 104.930 92.505  67.624  1.00 213.20 ? 50  ILE B CG1 1 
ATOM   3711  C  CG2 . ILE B 2 50  ? 103.906 90.384  68.419  1.00 232.95 ? 50  ILE B CG2 1 
ATOM   3712  C  CD1 . ILE B 2 50  ? 103.932 93.424  68.261  1.00 195.47 ? 50  ILE B CD1 1 
ATOM   3713  N  N   . THR B 2 51  ? 105.294 87.925  66.034  1.00 216.19 ? 51  THR B N   1 
ATOM   3714  C  CA  . THR B 2 51  ? 104.738 86.597  65.767  1.00 264.70 ? 51  THR B CA  1 
ATOM   3715  C  C   . THR B 2 51  ? 103.866 86.178  66.946  1.00 206.06 ? 51  THR B C   1 
ATOM   3716  O  O   . THR B 2 51  ? 104.071 86.669  68.047  1.00 238.97 ? 51  THR B O   1 
ATOM   3717  C  CB  . THR B 2 51  ? 105.827 85.556  65.417  1.00 296.76 ? 51  THR B CB  1 
ATOM   3718  O  OG1 . THR B 2 51  ? 105.209 84.289  65.179  1.00 294.67 ? 51  THR B OG1 1 
ATOM   3719  C  CG2 . THR B 2 51  ? 106.899 85.331  66.461  1.00 264.13 ? 51  THR B CG2 1 
ATOM   3720  N  N   . LEU B 2 52  ? 102.928 85.244  66.705  1.00 190.96 ? 52  LEU B N   1 
ATOM   3721  C  CA  . LEU B 2 52  ? 101.958 84.783  67.689  1.00 202.66 ? 52  LEU B CA  1 
ATOM   3722  C  C   . LEU B 2 52  ? 102.573 84.514  69.074  1.00 223.41 ? 52  LEU B C   1 
ATOM   3723  O  O   . LEU B 2 52  ? 101.994 84.964  70.061  1.00 228.16 ? 52  LEU B O   1 
ATOM   3724  C  CB  . LEU B 2 52  ? 101.315 83.485  67.183  1.00 240.07 ? 52  LEU B CB  1 
ATOM   3725  C  CG  . LEU B 2 52  ? 100.329 82.842  68.161  1.00 215.42 ? 52  LEU B CG  1 
ATOM   3726  C  CD1 . LEU B 2 52  ? 99.132  83.748  68.232  1.00 141.78 ? 52  LEU B CD1 1 
ATOM   3727  C  CD2 . LEU B 2 52  ? 99.947  81.400  67.803  1.00 205.70 ? 52  LEU B CD2 1 
ATOM   3728  N  N   . LEU B 2 53  ? 103.698 83.773  69.183  1.00 199.11 ? 53  LEU B N   1 
ATOM   3729  C  CA  . LEU B 2 53  ? 104.243 83.430  70.496  1.00 191.85 ? 53  LEU B CA  1 
ATOM   3730  C  C   . LEU B 2 53  ? 104.770 84.685  71.201  1.00 154.30 ? 53  LEU B C   1 
ATOM   3731  O  O   . LEU B 2 53  ? 104.664 84.779  72.427  1.00 228.20 ? 53  LEU B O   1 
ATOM   3732  C  CB  . LEU B 2 53  ? 105.314 82.333  70.371  1.00 265.23 ? 53  LEU B CB  1 
ATOM   3733  C  CG  . LEU B 2 53  ? 104.845 80.982  69.802  1.00 344.78 ? 53  LEU B CG  1 
ATOM   3734  C  CD1 . LEU B 2 53  ? 106.037 80.069  69.571  1.00 422.32 ? 53  LEU B CD1 1 
ATOM   3735  C  CD2 . LEU B 2 53  ? 103.823 80.248  70.683  1.00 281.61 ? 53  LEU B CD2 1 
ATOM   3736  N  N   . ASN B 2 54  ? 105.314 85.657  70.452  1.00 162.23 ? 54  ASN B N   1 
ATOM   3737  C  CA  . ASN B 2 54  ? 105.724 86.948  71.020  1.00 170.32 ? 54  ASN B CA  1 
ATOM   3738  C  C   . ASN B 2 54  ? 104.504 87.807  71.373  1.00 139.53 ? 54  ASN B C   1 
ATOM   3739  O  O   . ASN B 2 54  ? 104.544 88.583  72.321  1.00 200.47 ? 54  ASN B O   1 
ATOM   3740  C  CB  . ASN B 2 54  ? 106.755 87.637  70.118  1.00 190.12 ? 54  ASN B CB  1 
ATOM   3741  C  CG  . ASN B 2 54  ? 108.094 86.907  70.103  1.00 249.70 ? 54  ASN B CG  1 
ATOM   3742  O  OD1 . ASN B 2 54  ? 108.284 85.851  70.727  1.00 156.17 ? 54  ASN B OD1 1 
ATOM   3743  N  ND2 . ASN B 2 54  ? 109.048 87.447  69.358  1.00 298.20 ? 54  ASN B ND2 1 
ATOM   3744  N  N   . GLY B 2 55  ? 103.404 87.670  70.640  1.00 168.68 ? 55  GLY B N   1 
ATOM   3745  C  CA  . GLY B 2 55  ? 102.140 88.278  71.029  1.00 160.81 ? 55  GLY B CA  1 
ATOM   3746  C  C   . GLY B 2 55  ? 101.606 87.716  72.326  1.00 141.76 ? 55  GLY B C   1 
ATOM   3747  O  O   . GLY B 2 55  ? 101.129 88.495  73.113  1.00 128.67 ? 55  GLY B O   1 
ATOM   3748  N  N   . VAL B 2 56  ? 101.711 86.395  72.521  1.00 145.98 ? 56  VAL B N   1 
ATOM   3749  C  CA  . VAL B 2 56  ? 101.404 85.775  73.803  1.00 172.07 ? 56  VAL B CA  1 
ATOM   3750  C  C   . VAL B 2 56  ? 102.375 86.266  74.877  1.00 157.96 ? 56  VAL B C   1 
ATOM   3751  O  O   . VAL B 2 56  ? 101.939 86.467  76.000  1.00 132.68 ? 56  VAL B O   1 
ATOM   3752  C  CB  . VAL B 2 56  ? 101.408 84.244  73.718  1.00 218.05 ? 56  VAL B CB  1 
ATOM   3753  C  CG1 . VAL B 2 56  ? 101.341 83.561  75.090  1.00 234.91 ? 56  VAL B CG1 1 
ATOM   3754  C  CG2 . VAL B 2 56  ? 100.280 83.792  72.820  1.00 189.56 ? 56  VAL B CG2 1 
ATOM   3755  N  N   . ALA B 2 57  ? 103.654 86.475  74.551  1.00 178.51 ? 57  ALA B N   1 
ATOM   3756  C  CA  . ALA B 2 57  ? 104.603 87.058  75.505  1.00 162.95 ? 57  ALA B CA  1 
ATOM   3757  C  C   . ALA B 2 57  ? 104.174 88.461  75.959  1.00 118.08 ? 57  ALA B C   1 
ATOM   3758  O  O   . ALA B 2 57  ? 104.174 88.745  77.137  1.00 152.93 ? 57  ALA B O   1 
ATOM   3759  C  CB  . ALA B 2 57  ? 105.998 87.074  74.938  1.00 135.65 ? 57  ALA B CB  1 
ATOM   3760  N  N   . ILE B 2 58  ? 103.782 89.343  75.058  1.00 119.46 ? 58  ILE B N   1 
ATOM   3761  C  CA  . ILE B 2 58  ? 103.408 90.708  75.404  1.00 110.71 ? 58  ILE B CA  1 
ATOM   3762  C  C   . ILE B 2 58  ? 102.193 90.744  76.333  1.00 109.53 ? 58  ILE B C   1 
ATOM   3763  O  O   . ILE B 2 58  ? 102.077 91.691  77.092  1.00 130.40 ? 58  ILE B O   1 
ATOM   3764  C  CB  . ILE B 2 58  ? 103.169 91.553  74.124  1.00 153.37 ? 58  ILE B CB  1 
ATOM   3765  C  CG1 . ILE B 2 58  ? 104.491 91.777  73.360  1.00 174.48 ? 58  ILE B CG1 1 
ATOM   3766  C  CG2 . ILE B 2 58  ? 102.399 92.878  74.416  1.00 121.26 ? 58  ILE B CG2 1 
ATOM   3767  C  CD1 . ILE B 2 58  ? 104.359 91.914  71.865  1.00 200.51 ? 58  ILE B CD1 1 
ATOM   3768  N  N   . ILE B 2 59  ? 101.292 89.760  76.257  1.00 108.67 ? 59  ILE B N   1 
ATOM   3769  C  CA  . ILE B 2 59  ? 100.105 89.738  77.100  1.00 148.85 ? 59  ILE B CA  1 
ATOM   3770  C  C   . ILE B 2 59  ? 100.383 88.975  78.394  1.00 142.78 ? 59  ILE B C   1 
ATOM   3771  O  O   . ILE B 2 59  ? 100.130 89.523  79.455  1.00 173.98 ? 59  ILE B O   1 
ATOM   3772  C  CB  . ILE B 2 59  ? 98.861  89.254  76.337  1.00 154.10 ? 59  ILE B CB  1 
ATOM   3773  C  CG1 . ILE B 2 59  ? 97.597  89.345  77.183  1.00 130.46 ? 59  ILE B CG1 1 
ATOM   3774  C  CG2 . ILE B 2 59  ? 99.023  87.856  75.780  1.00 172.61 ? 59  ILE B CG2 1 
ATOM   3775  C  CD1 . ILE B 2 59  ? 96.357  89.400  76.313  1.00 178.49 ? 59  ILE B CD1 1 
ATOM   3776  N  N   . VAL B 2 60  ? 100.926 87.762  78.369  1.00 146.48 ? 60  VAL B N   1 
ATOM   3777  C  CA  . VAL B 2 60  ? 101.188 87.056  79.614  1.00 133.15 ? 60  VAL B CA  1 
ATOM   3778  C  C   . VAL B 2 60  ? 102.243 87.806  80.426  1.00 124.51 ? 60  VAL B C   1 
ATOM   3779  O  O   . VAL B 2 60  ? 102.142 87.813  81.645  1.00 237.53 ? 60  VAL B O   1 
ATOM   3780  C  CB  . VAL B 2 60  ? 101.614 85.596  79.364  1.00 165.82 ? 60  VAL B CB  1 
ATOM   3781  C  CG1 . VAL B 2 60  ? 103.055 85.442  78.899  1.00 194.61 ? 60  VAL B CG1 1 
ATOM   3782  C  CG2 . VAL B 2 60  ? 101.423 84.751  80.591  1.00 176.91 ? 60  VAL B CG2 1 
ATOM   3783  N  N   . GLY B 2 61  ? 103.254 88.430  79.799  1.00 132.09 ? 61  GLY B N   1 
ATOM   3784  C  CA  . GLY B 2 61  ? 104.322 89.146  80.500  1.00 165.84 ? 61  GLY B CA  1 
ATOM   3785  C  C   . GLY B 2 61  ? 103.816 90.357  81.282  1.00 154.51 ? 61  GLY B C   1 
ATOM   3786  O  O   . GLY B 2 61  ? 104.335 90.674  82.359  1.00 155.81 ? 61  GLY B O   1 
ATOM   3787  N  N   . THR B 2 62  ? 102.781 91.006  80.754  1.00 113.40 ? 62  THR B N   1 
ATOM   3788  C  CA  . THR B 2 62  ? 102.254 92.198  81.400  1.00 147.72 ? 62  THR B CA  1 
ATOM   3789  C  C   . THR B 2 62  ? 101.063 91.868  82.314  1.00 117.64 ? 62  THR B C   1 
ATOM   3790  O  O   . THR B 2 62  ? 100.745 92.700  83.150  1.00 181.95 ? 62  THR B O   1 
ATOM   3791  C  CB  . THR B 2 62  ? 102.001 93.300  80.353  1.00 157.18 ? 62  THR B CB  1 
ATOM   3792  O  OG1 . THR B 2 62  ? 101.931 94.591  80.962  1.00 173.63 ? 62  THR B OG1 1 
ATOM   3793  C  CG2 . THR B 2 62  ? 100.707 93.145  79.602  1.00 204.11 ? 62  THR B CG2 1 
ATOM   3794  N  N   . ILE B 2 63  ? 100.395 90.708  82.174  1.00 125.21 ? 63  ILE B N   1 
ATOM   3795  C  CA  . ILE B 2 63  ? 99.359  90.295  83.114  1.00 136.24 ? 63  ILE B CA  1 
ATOM   3796  C  C   . ILE B 2 63  ? 100.009 89.738  84.369  1.00 125.96 ? 63  ILE B C   1 
ATOM   3797  O  O   . ILE B 2 63  ? 99.707  90.225  85.456  1.00 163.37 ? 63  ILE B O   1 
ATOM   3798  C  CB  . ILE B 2 63  ? 98.358  89.284  82.536  1.00 145.70 ? 63  ILE B CB  1 
ATOM   3799  C  CG1 . ILE B 2 63  ? 97.506  89.844  81.391  1.00 144.63 ? 63  ILE B CG1 1 
ATOM   3800  C  CG2 . ILE B 2 63  ? 97.470  88.780  83.649  1.00 162.70 ? 63  ILE B CG2 1 
ATOM   3801  C  CD1 . ILE B 2 63  ? 96.863  88.751  80.537  1.00 175.63 ? 63  ILE B CD1 1 
ATOM   3802  N  N   . ILE B 2 64  ? 100.886 88.752  84.237  1.00 107.03 ? 64  ILE B N   1 
ATOM   3803  C  CA  . ILE B 2 64  ? 101.376 88.018  85.401  1.00 146.36 ? 64  ILE B CA  1 
ATOM   3804  C  C   . ILE B 2 64  ? 102.058 88.960  86.405  1.00 146.44 ? 64  ILE B C   1 
ATOM   3805  O  O   . ILE B 2 64  ? 101.984 88.721  87.617  1.00 139.26 ? 64  ILE B O   1 
ATOM   3806  C  CB  . ILE B 2 64  ? 102.281 86.850  84.924  1.00 152.29 ? 64  ILE B CB  1 
ATOM   3807  C  CG1 . ILE B 2 64  ? 101.480 85.774  84.190  1.00 196.68 ? 64  ILE B CG1 1 
ATOM   3808  C  CG2 . ILE B 2 64  ? 103.116 86.189  85.981  1.00 101.36 ? 64  ILE B CG2 1 
ATOM   3809  C  CD1 . ILE B 2 64  ? 100.472 85.013  85.001  1.00 213.54 ? 64  ILE B CD1 1 
ATOM   3810  N  N   . GLY B 2 65  ? 102.727 90.007  85.912  1.00 149.03 ? 65  GLY B N   1 
ATOM   3811  C  CA  . GLY B 2 65  ? 103.149 91.137  86.743  1.00 218.26 ? 65  GLY B CA  1 
ATOM   3812  C  C   . GLY B 2 65  ? 103.940 90.802  88.019  1.00 197.48 ? 65  GLY B C   1 
ATOM   3813  O  O   . GLY B 2 65  ? 104.662 89.795  88.072  1.00 113.62 ? 65  GLY B O   1 
ATOM   3814  N  N   . SER B 2 66  ? 103.813 91.689  89.017  1.00 182.38 ? 66  SER B N   1 
ATOM   3815  C  CA  . SER B 2 66  ? 104.152 91.413  90.406  1.00 171.06 ? 66  SER B CA  1 
ATOM   3816  C  C   . SER B 2 66  ? 103.023 90.679  91.127  1.00 141.46 ? 66  SER B C   1 
ATOM   3817  O  O   . SER B 2 66  ? 103.292 90.030  92.116  1.00 125.52 ? 66  SER B O   1 
ATOM   3818  C  CB  . SER B 2 66  ? 104.454 92.699  91.139  1.00 220.91 ? 66  SER B CB  1 
ATOM   3819  O  OG  . SER B 2 66  ? 103.291 93.523  91.267  1.00 199.09 ? 66  SER B OG  1 
ATOM   3820  N  N   . GLY B 2 67  ? 101.780 90.787  90.624  1.00 176.71 ? 67  GLY B N   1 
ATOM   3821  C  CA  . GLY B 2 67  ? 100.553 90.572  91.387  1.00 147.31 ? 67  GLY B CA  1 
ATOM   3822  C  C   . GLY B 2 67  ? 100.508 89.227  92.114  1.00 144.31 ? 67  GLY B C   1 
ATOM   3823  O  O   . GLY B 2 67  ? 100.424 89.231  93.319  1.00 175.85 ? 67  GLY B O   1 
ATOM   3824  N  N   . ILE B 2 68  ? 100.594 88.092  91.419  1.00 145.45 ? 68  ILE B N   1 
ATOM   3825  C  CA  . ILE B 2 68  ? 100.395 86.784  92.029  1.00 127.10 ? 68  ILE B CA  1 
ATOM   3826  C  C   . ILE B 2 68  ? 101.429 86.454  93.108  1.00 116.07 ? 68  ILE B C   1 
ATOM   3827  O  O   . ILE B 2 68  ? 101.129 85.710  94.032  1.00 179.99 ? 68  ILE B O   1 
ATOM   3828  C  CB  . ILE B 2 68  ? 100.428 85.692  90.951  1.00 173.01 ? 68  ILE B CB  1 
ATOM   3829  C  CG1 . ILE B 2 68  ? 99.819  84.389  91.457  1.00 233.50 ? 68  ILE B CG1 1 
ATOM   3830  C  CG2 . ILE B 2 68  ? 101.825 85.456  90.406  1.00 147.00 ? 68  ILE B CG2 1 
ATOM   3831  C  CD1 . ILE B 2 68  ? 98.391  84.524  91.907  1.00 229.12 ? 68  ILE B CD1 1 
ATOM   3832  N  N   . PHE B 2 69  ? 102.623 87.004  93.043  1.00 112.28 ? 69  PHE B N   1 
ATOM   3833  C  CA  . PHE B 2 69  ? 103.600 86.774  94.083  1.00 118.42 ? 69  PHE B CA  1 
ATOM   3834  C  C   . PHE B 2 69  ? 103.444 87.600  95.390  1.00 128.95 ? 69  PHE B C   1 
ATOM   3835  O  O   . PHE B 2 69  ? 104.188 87.327  96.313  1.00 180.11 ? 69  PHE B O   1 
ATOM   3836  C  CB  . PHE B 2 69  ? 104.952 87.113  93.486  1.00 163.50 ? 69  PHE B CB  1 
ATOM   3837  C  CG  . PHE B 2 69  ? 105.338 86.299  92.292  1.00 130.95 ? 69  PHE B CG  1 
ATOM   3838  C  CD1 . PHE B 2 69  ? 105.771 84.996  92.431  1.00 181.78 ? 69  PHE B CD1 1 
ATOM   3839  C  CD2 . PHE B 2 69  ? 105.301 86.868  91.047  1.00 154.48 ? 69  PHE B CD2 1 
ATOM   3840  C  CE1 . PHE B 2 69  ? 106.161 84.258  91.334  1.00 209.52 ? 69  PHE B CE1 1 
ATOM   3841  C  CE2 . PHE B 2 69  ? 105.689 86.127  89.951  1.00 205.91 ? 69  PHE B CE2 1 
ATOM   3842  C  CZ  . PHE B 2 69  ? 106.113 84.827  90.095  1.00 179.79 ? 69  PHE B CZ  1 
ATOM   3843  N  N   . VAL B 2 70  ? 102.555 88.607  95.489  1.00 139.43 ? 70  VAL B N   1 
ATOM   3844  C  CA  . VAL B 2 70  ? 102.380 89.458  96.684  1.00 140.71 ? 70  VAL B CA  1 
ATOM   3845  C  C   . VAL B 2 70  ? 100.898 89.805  96.963  1.00 138.59 ? 70  VAL B C   1 
ATOM   3846  O  O   . VAL B 2 70  ? 100.553 90.258  98.041  1.00 137.71 ? 70  VAL B O   1 
ATOM   3847  C  CB  . VAL B 2 70  ? 103.211 90.768  96.559  1.00 199.89 ? 70  VAL B CB  1 
ATOM   3848  C  CG1 . VAL B 2 70  ? 104.686 90.539  96.180  1.00 170.56 ? 70  VAL B CG1 1 
ATOM   3849  C  CG2 . VAL B 2 70  ? 102.571 91.772  95.586  1.00 254.72 ? 70  VAL B CG2 1 
ATOM   3850  N  N   . THR B 2 71  ? 99.972  89.625  95.995  1.00 171.62 ? 71  THR B N   1 
ATOM   3851  C  CA  . THR B 2 71  ? 98.565  90.031  96.077  1.00 160.48 ? 71  THR B CA  1 
ATOM   3852  C  C   . THR B 2 71  ? 97.644  89.010  96.737  1.00 133.38 ? 71  THR B C   1 
ATOM   3853  O  O   . THR B 2 71  ? 96.600  89.444  97.205  1.00 200.88 ? 71  THR B O   1 
ATOM   3854  C  CB  . THR B 2 71  ? 97.952  90.306  94.697  1.00 222.76 ? 71  THR B CB  1 
ATOM   3855  O  OG1 . THR B 2 71  ? 98.771  91.314  94.099  1.00 340.94 ? 71  THR B OG1 1 
ATOM   3856  C  CG2 . THR B 2 71  ? 96.528  90.829  94.698  1.00 242.25 ? 71  THR B CG2 1 
ATOM   3857  N  N   . PRO B 2 72  ? 97.909  87.687  96.873  1.00 127.62 ? 72  PRO B N   1 
ATOM   3858  C  CA  . PRO B 2 72  ? 96.987  86.768  97.570  1.00 179.33 ? 72  PRO B CA  1 
ATOM   3859  C  C   . PRO B 2 72  ? 96.423  87.249  98.918  1.00 196.05 ? 72  PRO B C   1 
ATOM   3860  O  O   . PRO B 2 72  ? 95.233  87.085  99.177  1.00 183.41 ? 72  PRO B O   1 
ATOM   3861  C  CB  . PRO B 2 72  ? 97.856  85.508  97.813  1.00 155.49 ? 72  PRO B CB  1 
ATOM   3862  C  CG  . PRO B 2 72  ? 98.775  85.504  96.679  1.00 127.58 ? 72  PRO B CG  1 
ATOM   3863  C  CD  . PRO B 2 72  ? 99.091  86.961  96.421  1.00 117.99 ? 72  PRO B CD  1 
ATOM   3864  N  N   . THR B 2 73  ? 97.285  87.833  99.763  1.00 128.18 ? 73  THR B N   1 
ATOM   3865  C  CA  . THR B 2 73  ? 96.902  88.461  100.996 1.00 143.44 ? 73  THR B CA  1 
ATOM   3866  C  C   . THR B 2 73  ? 95.641  89.339  100.846 1.00 174.67 ? 73  THR B C   1 
ATOM   3867  O  O   . THR B 2 73  ? 94.783  89.281  101.732 1.00 326.53 ? 73  THR B O   1 
ATOM   3868  C  CB  . THR B 2 73  ? 98.101  89.246  101.563 1.00 253.23 ? 73  THR B CB  1 
ATOM   3869  O  OG1 . THR B 2 73  ? 97.802  89.623  102.902 1.00 377.93 ? 73  THR B OG1 1 
ATOM   3870  C  CG2 . THR B 2 73  ? 98.459  90.517  100.825 1.00 278.01 ? 73  THR B CG2 1 
ATOM   3871  N  N   . GLY B 2 74  ? 95.526  90.150  99.773  1.00 173.20 ? 74  GLY B N   1 
ATOM   3872  C  CA  . GLY B 2 74  ? 94.423  91.080  99.527  1.00 205.71 ? 74  GLY B CA  1 
ATOM   3873  C  C   . GLY B 2 74  ? 93.062  90.391  99.350  1.00 235.07 ? 74  GLY B C   1 
ATOM   3874  O  O   . GLY B 2 74  ? 92.020  90.918  99.776  1.00 251.74 ? 74  GLY B O   1 
ATOM   3875  N  N   . VAL B 2 75  ? 93.080  89.205  98.734  1.00 201.75 ? 75  VAL B N   1 
ATOM   3876  C  CA  . VAL B 2 75  ? 91.868  88.419  98.566  1.00 253.61 ? 75  VAL B CA  1 
ATOM   3877  C  C   . VAL B 2 75  ? 91.504  87.710  99.881  1.00 234.24 ? 75  VAL B C   1 
ATOM   3878  O  O   . VAL B 2 75  ? 90.331  87.728  100.231 1.00 216.60 ? 75  VAL B O   1 
ATOM   3879  C  CB  . VAL B 2 75  ? 92.004  87.461  97.366  1.00 291.63 ? 75  VAL B CB  1 
ATOM   3880  C  CG1 . VAL B 2 75  ? 90.933  86.394  97.347  1.00 324.55 ? 75  VAL B CG1 1 
ATOM   3881  C  CG2 . VAL B 2 75  ? 91.991  88.228  96.063  1.00 273.86 ? 75  VAL B CG2 1 
ATOM   3882  N  N   . LEU B 2 76  ? 92.448  87.098  100.624 1.00 178.87 ? 76  LEU B N   1 
ATOM   3883  C  CA  . LEU B 2 76  ? 92.118  86.501  101.921 1.00 150.59 ? 76  LEU B CA  1 
ATOM   3884  C  C   . LEU B 2 76  ? 91.564  87.554  102.895 1.00 151.40 ? 76  LEU B C   1 
ATOM   3885  O  O   . LEU B 2 76  ? 90.683  87.243  103.669 1.00 160.70 ? 76  LEU B O   1 
ATOM   3886  C  CB  . LEU B 2 76  ? 93.348  85.831  102.569 1.00 210.07 ? 76  LEU B CB  1 
ATOM   3887  C  CG  . LEU B 2 76  ? 93.694  84.394  102.182 1.00 208.82 ? 76  LEU B CG  1 
ATOM   3888  C  CD1 . LEU B 2 76  ? 92.552  83.432  102.468 1.00 178.17 ? 76  LEU B CD1 1 
ATOM   3889  C  CD2 . LEU B 2 76  ? 94.084  84.344  100.733 1.00 259.04 ? 76  LEU B CD2 1 
ATOM   3890  N  N   . LYS B 2 77  ? 92.059  88.798  102.880 1.00 241.55 ? 77  LYS B N   1 
ATOM   3891  C  CA  . LYS B 2 77  ? 91.583  89.838  103.786 1.00 241.94 ? 77  LYS B CA  1 
ATOM   3892  C  C   . LYS B 2 77  ? 90.069  90.044  103.657 1.00 184.33 ? 77  LYS B C   1 
ATOM   3893  O  O   . LYS B 2 77  ? 89.395  90.194  104.682 1.00 267.96 ? 77  LYS B O   1 
ATOM   3894  C  CB  . LYS B 2 77  ? 92.347  91.139  103.526 1.00 313.99 ? 77  LYS B CB  1 
ATOM   3895  C  CG  . LYS B 2 77  ? 92.108  92.232  104.557 1.00 349.16 ? 77  LYS B CG  1 
ATOM   3896  C  CD  . LYS B 2 77  ? 93.074  93.395  104.462 1.00 412.21 ? 77  LYS B CD  1 
ATOM   3897  C  CE  . LYS B 2 77  ? 92.955  94.227  103.199 1.00 474.33 ? 77  LYS B CE  1 
ATOM   3898  N  NZ  . LYS B 2 77  ? 91.739  95.078  103.190 1.00 490.33 ? 77  LYS B NZ  1 
ATOM   3899  N  N   . GLU B 2 78  ? 89.541  90.045  102.419 1.00 133.41 ? 78  GLU B N   1 
ATOM   3900  C  CA  . GLU B 2 78  ? 88.118  90.265  102.174 1.00 225.69 ? 78  GLU B CA  1 
ATOM   3901  C  C   . GLU B 2 78  ? 87.289  88.972  102.004 1.00 221.88 ? 78  GLU B C   1 
ATOM   3902  O  O   . GLU B 2 78  ? 86.062  89.011  102.099 1.00 180.24 ? 78  GLU B O   1 
ATOM   3903  C  CB  . GLU B 2 78  ? 87.994  91.164  100.943 1.00 274.62 ? 78  GLU B CB  1 
ATOM   3904  C  CG  . GLU B 2 78  ? 88.689  92.516  101.057 1.00 259.42 ? 78  GLU B CG  1 
ATOM   3905  C  CD  . GLU B 2 78  ? 88.359  93.328  102.302 1.00 293.89 ? 78  GLU B CD  1 
ATOM   3906  O  OE1 . GLU B 2 78  ? 87.171  93.338  102.704 1.00 244.20 ? 78  GLU B OE1 1 
ATOM   3907  O  OE2 . GLU B 2 78  ? 89.284  93.957  102.865 1.00 348.11 ? 78  GLU B OE2 1 
ATOM   3908  N  N   . ALA B 2 79  ? 87.924  87.817  101.754 1.00 154.44 ? 79  ALA B N   1 
ATOM   3909  C  CA  . ALA B 2 79  ? 87.235  86.533  101.679 1.00 196.51 ? 79  ALA B CA  1 
ATOM   3910  C  C   . ALA B 2 79  ? 87.184  85.779  103.022 1.00 198.77 ? 79  ALA B C   1 
ATOM   3911  O  O   . ALA B 2 79  ? 86.241  85.029  103.298 1.00 183.09 ? 79  ALA B O   1 
ATOM   3912  C  CB  . ALA B 2 79  ? 87.935  85.714  100.638 1.00 276.29 ? 79  ALA B CB  1 
ATOM   3913  N  N   . GLY B 2 80  ? 88.221  85.949  103.859 1.00 249.55 ? 80  GLY B N   1 
ATOM   3914  C  CA  . GLY B 2 80  ? 88.393  85.199  105.100 1.00 251.17 ? 80  GLY B CA  1 
ATOM   3915  C  C   . GLY B 2 80  ? 88.821  83.736  104.911 1.00 212.34 ? 80  GLY B C   1 
ATOM   3916  O  O   . GLY B 2 80  ? 89.595  83.207  105.714 1.00 176.67 ? 80  GLY B O   1 
ATOM   3917  N  N   . SER B 2 81  ? 88.320  83.093  103.844 1.00 154.17 ? 81  SER B N   1 
ATOM   3918  C  CA  . SER B 2 81  ? 88.308  81.648  103.709 1.00 215.28 ? 81  SER B CA  1 
ATOM   3919  C  C   . SER B 2 81  ? 89.116  81.240  102.490 1.00 198.72 ? 81  SER B C   1 
ATOM   3920  O  O   . SER B 2 81  ? 88.837  81.774  101.426 1.00 183.03 ? 81  SER B O   1 
ATOM   3921  C  CB  . SER B 2 81  ? 86.873  81.165  103.605 1.00 297.30 ? 81  SER B CB  1 
ATOM   3922  O  OG  . SER B 2 81  ? 86.772  79.774  103.354 1.00 357.19 ? 81  SER B OG  1 
ATOM   3923  N  N   . PRO B 2 82  ? 90.104  80.307  102.584 1.00 209.41 ? 82  PRO B N   1 
ATOM   3924  C  CA  . PRO B 2 82  ? 90.797  79.773  101.403 1.00 247.91 ? 82  PRO B CA  1 
ATOM   3925  C  C   . PRO B 2 82  ? 89.854  79.295  100.293 1.00 212.59 ? 82  PRO B C   1 
ATOM   3926  O  O   . PRO B 2 82  ? 90.170  79.464  99.126  1.00 208.09 ? 82  PRO B O   1 
ATOM   3927  C  CB  . PRO B 2 82  ? 91.655  78.606  101.941 1.00 215.26 ? 82  PRO B CB  1 
ATOM   3928  C  CG  . PRO B 2 82  ? 91.887  78.974  103.390 1.00 221.28 ? 82  PRO B CG  1 
ATOM   3929  C  CD  . PRO B 2 82  ? 90.628  79.707  103.817 1.00 199.24 ? 82  PRO B CD  1 
ATOM   3930  N  N   . GLY B 2 83  ? 88.704  78.726  100.645 1.00 210.55 ? 83  GLY B N   1 
ATOM   3931  C  CA  . GLY B 2 83  ? 87.709  78.322  99.663  1.00 321.77 ? 83  GLY B CA  1 
ATOM   3932  C  C   . GLY B 2 83  ? 87.118  79.500  98.887  1.00 283.77 ? 83  GLY B C   1 
ATOM   3933  O  O   . GLY B 2 83  ? 87.128  79.458  97.655  1.00 365.18 ? 83  GLY B O   1 
ATOM   3934  N  N   . LEU B 2 84  ? 86.619  80.535  99.589  1.00 186.24 ? 84  LEU B N   1 
ATOM   3935  C  CA  . LEU B 2 84  ? 86.018  81.680  98.906  1.00 206.52 ? 84  LEU B CA  1 
ATOM   3936  C  C   . LEU B 2 84  ? 87.091  82.423  98.108  1.00 209.30 ? 84  LEU B C   1 
ATOM   3937  O  O   . LEU B 2 84  ? 86.826  82.902  96.996  1.00 186.32 ? 84  LEU B O   1 
ATOM   3938  C  CB  . LEU B 2 84  ? 85.299  82.612  99.890  1.00 231.28 ? 84  LEU B CB  1 
ATOM   3939  C  CG  . LEU B 2 84  ? 84.723  83.911  99.295  1.00 260.35 ? 84  LEU B CG  1 
ATOM   3940  C  CD1 . LEU B 2 84  ? 83.732  83.686  98.155  1.00 271.94 ? 84  LEU B CD1 1 
ATOM   3941  C  CD2 . LEU B 2 84  ? 84.034  84.722  100.373 1.00 279.47 ? 84  LEU B CD2 1 
ATOM   3942  N  N   . ALA B 2 85  ? 88.305  82.509  98.665  1.00 211.38 ? 85  ALA B N   1 
ATOM   3943  C  CA  . ALA B 2 85  ? 89.428  83.118  97.969  1.00 242.21 ? 85  ALA B CA  1 
ATOM   3944  C  C   . ALA B 2 85  ? 89.652  82.399  96.645  1.00 199.24 ? 85  ALA B C   1 
ATOM   3945  O  O   . ALA B 2 85  ? 89.662  83.022  95.579  1.00 283.28 ? 85  ALA B O   1 
ATOM   3946  C  CB  . ALA B 2 85  ? 90.660  83.082  98.842  1.00 251.38 ? 85  ALA B CB  1 
ATOM   3947  N  N   . LEU B 2 86  ? 89.820  81.080  96.703  1.00 152.54 ? 86  LEU B N   1 
ATOM   3948  C  CA  . LEU B 2 86  ? 90.202  80.346  95.511  1.00 187.86 ? 86  LEU B CA  1 
ATOM   3949  C  C   . LEU B 2 86  ? 89.080  80.377  94.464  1.00 175.54 ? 86  LEU B C   1 
ATOM   3950  O  O   . LEU B 2 86  ? 89.369  80.259  93.265  1.00 199.60 ? 86  LEU B O   1 
ATOM   3951  C  CB  . LEU B 2 86  ? 90.629  78.947  95.940  1.00 168.39 ? 86  LEU B CB  1 
ATOM   3952  C  CG  . LEU B 2 86  ? 91.400  78.184  94.868  1.00 184.85 ? 86  LEU B CG  1 
ATOM   3953  C  CD1 . LEU B 2 86  ? 92.494  77.395  95.496  1.00 149.27 ? 86  LEU B CD1 1 
ATOM   3954  C  CD2 . LEU B 2 86  ? 90.490  77.221  94.104  1.00 294.24 ? 86  LEU B CD2 1 
ATOM   3955  N  N   . VAL B 2 87  ? 87.827  80.589  94.895  1.00 165.66 ? 87  VAL B N   1 
ATOM   3956  C  CA  . VAL B 2 87  ? 86.717  80.793  93.971  1.00 223.16 ? 87  VAL B CA  1 
ATOM   3957  C  C   . VAL B 2 87  ? 86.804  82.178  93.332  1.00 178.91 ? 87  VAL B C   1 
ATOM   3958  O  O   . VAL B 2 87  ? 86.634  82.246  92.107  1.00 305.90 ? 87  VAL B O   1 
ATOM   3959  C  CB  . VAL B 2 87  ? 85.348  80.541  94.636  1.00 346.48 ? 87  VAL B CB  1 
ATOM   3960  C  CG1 . VAL B 2 87  ? 84.165  81.077  93.828  1.00 347.54 ? 87  VAL B CG1 1 
ATOM   3961  C  CG2 . VAL B 2 87  ? 85.177  79.051  94.911  1.00 403.38 ? 87  VAL B CG2 1 
ATOM   3962  N  N   . VAL B 2 88  ? 87.046  83.271  94.075  1.00 120.37 ? 88  VAL B N   1 
ATOM   3963  C  CA  . VAL B 2 88  ? 87.030  84.582  93.399  1.00 185.59 ? 88  VAL B CA  1 
ATOM   3964  C  C   . VAL B 2 88  ? 88.231  84.717  92.443  1.00 180.62 ? 88  VAL B C   1 
ATOM   3965  O  O   . VAL B 2 88  ? 88.157  85.428  91.451  1.00 107.58 ? 88  VAL B O   1 
ATOM   3966  C  CB  . VAL B 2 88  ? 86.906  85.799  94.342  1.00 200.91 ? 88  VAL B CB  1 
ATOM   3967  C  CG1 . VAL B 2 88  ? 85.566  85.763  95.044  1.00 251.06 ? 88  VAL B CG1 1 
ATOM   3968  C  CG2 . VAL B 2 88  ? 88.042  85.940  95.345  1.00 203.86 ? 88  VAL B CG2 1 
ATOM   3969  N  N   . TRP B 2 89  ? 89.348  84.033  92.701  1.00 199.66 ? 89  TRP B N   1 
ATOM   3970  C  CA  . TRP B 2 89  ? 90.444  83.968  91.739  1.00 179.73 ? 89  TRP B CA  1 
ATOM   3971  C  C   . TRP B 2 89  ? 90.034  83.364  90.408  1.00 163.32 ? 89  TRP B C   1 
ATOM   3972  O  O   . TRP B 2 89  ? 90.468  83.849  89.369  1.00 223.32 ? 89  TRP B O   1 
ATOM   3973  C  CB  . TRP B 2 89  ? 91.630  83.167  92.293  1.00 184.47 ? 89  TRP B CB  1 
ATOM   3974  C  CG  . TRP B 2 89  ? 92.544  83.996  93.144  1.00 203.40 ? 89  TRP B CG  1 
ATOM   3975  C  CD1 . TRP B 2 89  ? 92.601  83.993  94.507  1.00 280.99 ? 89  TRP B CD1 1 
ATOM   3976  C  CD2 . TRP B 2 89  ? 93.534  84.945  92.705  1.00 144.16 ? 89  TRP B CD2 1 
ATOM   3977  N  NE1 . TRP B 2 89  ? 93.556  84.868  94.941  1.00 234.84 ? 89  TRP B NE1 1 
ATOM   3978  C  CE2 . TRP B 2 89  ? 94.140  85.465  93.859  1.00 195.69 ? 89  TRP B CE2 1 
ATOM   3979  C  CE3 . TRP B 2 89  ? 93.974  85.404  91.467  1.00 223.54 ? 89  TRP B CE3 1 
ATOM   3980  C  CZ2 . TRP B 2 89  ? 95.154  86.417  93.807  1.00 264.75 ? 89  TRP B CZ2 1 
ATOM   3981  C  CZ3 . TRP B 2 89  ? 94.977  86.351  91.409  1.00 276.36 ? 89  TRP B CZ3 1 
ATOM   3982  C  CH2 . TRP B 2 89  ? 95.564  86.851  92.568  1.00 238.75 ? 89  TRP B CH2 1 
ATOM   3983  N  N   . ALA B 2 90  ? 89.260  82.280  90.440  1.00 143.02 ? 90  ALA B N   1 
ATOM   3984  C  CA  . ALA B 2 90  ? 88.708  81.712  89.222  1.00 167.48 ? 90  ALA B CA  1 
ATOM   3985  C  C   . ALA B 2 90  ? 87.680  82.655  88.595  1.00 179.60 ? 90  ALA B C   1 
ATOM   3986  O  O   . ALA B 2 90  ? 87.661  82.807  87.380  1.00 252.78 ? 90  ALA B O   1 
ATOM   3987  C  CB  . ALA B 2 90  ? 88.100  80.369  89.504  1.00 214.76 ? 90  ALA B CB  1 
ATOM   3988  N  N   . ALA B 2 91  ? 86.836  83.284  89.421  1.00 148.08 ? 91  ALA B N   1 
ATOM   3989  C  CA  . ALA B 2 91  ? 85.721  84.089  88.951  1.00 201.75 ? 91  ALA B CA  1 
ATOM   3990  C  C   . ALA B 2 91  ? 86.213  85.317  88.192  1.00 223.15 ? 91  ALA B C   1 
ATOM   3991  O  O   . ALA B 2 91  ? 85.738  85.564  87.094  1.00 246.68 ? 91  ALA B O   1 
ATOM   3992  C  CB  . ALA B 2 91  ? 84.824  84.483  90.104  1.00 277.85 ? 91  ALA B CB  1 
ATOM   3993  N  N   . CYS B 2 92  ? 87.158  86.087  88.738  1.00 220.45 ? 92  CYS B N   1 
ATOM   3994  C  CA  . CYS B 2 92  ? 87.596  87.279  88.015  1.00 195.75 ? 92  CYS B CA  1 
ATOM   3995  C  C   . CYS B 2 92  ? 88.492  86.847  86.849  1.00 174.73 ? 92  CYS B C   1 
ATOM   3996  O  O   . CYS B 2 92  ? 88.667  87.645  85.925  1.00 211.01 ? 92  CYS B O   1 
ATOM   3997  C  CB  . CYS B 2 92  ? 88.215  88.329  88.941  1.00 216.25 ? 92  CYS B CB  1 
ATOM   3998  S  SG  . CYS B 2 92  ? 89.602  87.741  89.946  1.00 220.16 ? 92  CYS B SG  1 
ATOM   3999  N  N   . GLY B 2 93  ? 89.029  85.600  86.862  1.00 133.15 ? 93  GLY B N   1 
ATOM   4000  C  CA  . GLY B 2 93  ? 89.598  84.973  85.669  1.00 158.46 ? 93  GLY B CA  1 
ATOM   4001  C  C   . GLY B 2 93  ? 88.612  84.892  84.500  1.00 182.69 ? 93  GLY B C   1 
ATOM   4002  O  O   . GLY B 2 93  ? 88.885  85.461  83.443  1.00 173.64 ? 93  GLY B O   1 
ATOM   4003  N  N   . VAL B 2 94  ? 87.467  84.219  84.690  1.00 189.41 ? 94  VAL B N   1 
ATOM   4004  C  CA  . VAL B 2 94  ? 86.499  84.069  83.607  1.00 190.52 ? 94  VAL B CA  1 
ATOM   4005  C  C   . VAL B 2 94  ? 85.910  85.426  83.208  1.00 176.63 ? 94  VAL B C   1 
ATOM   4006  O  O   . VAL B 2 94  ? 85.658  85.618  82.017  1.00 205.68 ? 94  VAL B O   1 
ATOM   4007  C  CB  . VAL B 2 94  ? 85.391  83.027  83.891  1.00 283.16 ? 94  VAL B CB  1 
ATOM   4008  C  CG1 . VAL B 2 94  ? 86.005  81.655  84.158  1.00 306.72 ? 94  VAL B CG1 1 
ATOM   4009  C  CG2 . VAL B 2 94  ? 84.417  83.398  85.006  1.00 320.25 ? 94  VAL B CG2 1 
ATOM   4010  N  N   . PHE B 2 95  ? 85.691  86.354  84.156  1.00 166.54 ? 95  PHE B N   1 
ATOM   4011  C  CA  . PHE B 2 95  ? 85.336  87.733  83.820  1.00 219.59 ? 95  PHE B CA  1 
ATOM   4012  C  C   . PHE B 2 95  ? 86.379  88.392  82.894  1.00 203.25 ? 95  PHE B C   1 
ATOM   4013  O  O   . PHE B 2 95  ? 86.026  89.048  81.902  1.00 147.50 ? 95  PHE B O   1 
ATOM   4014  C  CB  . PHE B 2 95  ? 85.098  88.553  85.095  1.00 199.81 ? 95  PHE B CB  1 
ATOM   4015  C  CG  . PHE B 2 95  ? 85.027  90.046  84.878  1.00 207.39 ? 95  PHE B CG  1 
ATOM   4016  C  CD1 . PHE B 2 95  ? 86.189  90.803  84.837  1.00 215.96 ? 95  PHE B CD1 1 
ATOM   4017  C  CD2 . PHE B 2 95  ? 83.815  90.706  84.699  1.00 222.71 ? 95  PHE B CD2 1 
ATOM   4018  C  CE1 . PHE B 2 95  ? 86.144  92.181  84.639  1.00 206.42 ? 95  PHE B CE1 1 
ATOM   4019  C  CE2 . PHE B 2 95  ? 83.776  92.079  84.494  1.00 215.81 ? 95  PHE B CE2 1 
ATOM   4020  C  CZ  . PHE B 2 95  ? 84.939  92.819  84.466  1.00 191.83 ? 95  PHE B CZ  1 
ATOM   4021  N  N   . SER B 2 96  ? 87.666  88.229  83.211  1.00 178.51 ? 96  SER B N   1 
ATOM   4022  C  CA  . SER B 2 96  ? 88.725  88.815  82.405  1.00 196.73 ? 96  SER B CA  1 
ATOM   4023  C  C   . SER B 2 96  ? 88.746  88.198  81.004  1.00 214.73 ? 96  SER B C   1 
ATOM   4024  O  O   . SER B 2 96  ? 88.969  88.933  80.042  1.00 151.52 ? 96  SER B O   1 
ATOM   4025  C  CB  . SER B 2 96  ? 90.058  88.673  83.108  1.00 226.33 ? 96  SER B CB  1 
ATOM   4026  O  OG  . SER B 2 96  ? 90.053  89.336  84.365  1.00 207.38 ? 96  SER B OG  1 
ATOM   4027  N  N   . ILE B 2 97  ? 88.526  86.868  80.888  1.00 216.45 ? 97  ILE B N   1 
ATOM   4028  C  CA  . ILE B 2 97  ? 88.430  86.191  79.594  1.00 167.09 ? 97  ILE B CA  1 
ATOM   4029  C  C   . ILE B 2 97  ? 87.299  86.800  78.790  1.00 136.00 ? 97  ILE B C   1 
ATOM   4030  O  O   . ILE B 2 97  ? 87.509  87.119  77.617  1.00 224.57 ? 97  ILE B O   1 
ATOM   4031  C  CB  . ILE B 2 97  ? 88.283  84.668  79.725  1.00 151.71 ? 97  ILE B CB  1 
ATOM   4032  C  CG1 . ILE B 2 97  ? 89.563  84.038  80.285  1.00 175.44 ? 97  ILE B CG1 1 
ATOM   4033  C  CG2 . ILE B 2 97  ? 87.936  84.036  78.393  1.00 214.09 ? 97  ILE B CG2 1 
ATOM   4034  C  CD1 . ILE B 2 97  ? 89.392  82.680  80.915  1.00 208.60 ? 97  ILE B CD1 1 
ATOM   4035  N  N   . VAL B 2 98  ? 86.146  86.985  79.423  1.00 130.06 ? 98  VAL B N   1 
ATOM   4036  C  CA  . VAL B 2 98  ? 85.014  87.609  78.743  1.00 192.08 ? 98  VAL B CA  1 
ATOM   4037  C  C   . VAL B 2 98  ? 85.313  89.035  78.246  1.00 195.07 ? 98  VAL B C   1 
ATOM   4038  O  O   . VAL B 2 98  ? 84.925  89.380  77.131  1.00 166.67 ? 98  VAL B O   1 
ATOM   4039  C  CB  . VAL B 2 98  ? 83.775  87.545  79.650  1.00 227.34 ? 98  VAL B CB  1 
ATOM   4040  C  CG1 . VAL B 2 98  ? 82.679  88.535  79.263  1.00 173.95 ? 98  VAL B CG1 1 
ATOM   4041  C  CG2 . VAL B 2 98  ? 83.264  86.109  79.678  1.00 290.80 ? 98  VAL B CG2 1 
ATOM   4042  N  N   . GLY B 2 99  ? 85.990  89.853  79.048  1.00 149.71 ? 99  GLY B N   1 
ATOM   4043  C  CA  . GLY B 2 99  ? 86.402  91.156  78.576  1.00 167.13 ? 99  GLY B CA  1 
ATOM   4044  C  C   . GLY B 2 99  ? 87.382  91.087  77.414  1.00 190.12 ? 99  GLY B C   1 
ATOM   4045  O  O   . GLY B 2 99  ? 87.208  91.789  76.429  1.00 187.37 ? 99  GLY B O   1 
ATOM   4046  N  N   . ALA B 2 100 ? 88.412  90.241  77.548  1.00 181.16 ? 100 ALA B N   1 
ATOM   4047  C  CA  . ALA B 2 100 ? 89.438  90.110  76.525  1.00 194.80 ? 100 ALA B CA  1 
ATOM   4048  C  C   . ALA B 2 100 ? 88.832  89.633  75.201  1.00 179.72 ? 100 ALA B C   1 
ATOM   4049  O  O   . ALA B 2 100 ? 89.254  90.073  74.131  1.00 95.47  ? 100 ALA B O   1 
ATOM   4050  C  CB  . ALA B 2 100 ? 90.535  89.218  77.032  1.00 175.76 ? 100 ALA B CB  1 
ATOM   4051  N  N   . LEU B 2 101 ? 87.814  88.776  75.267  1.00 192.96 ? 101 LEU B N   1 
ATOM   4052  C  CA  . LEU B 2 101 ? 87.105  88.390  74.054  1.00 186.47 ? 101 LEU B CA  1 
ATOM   4053  C  C   . LEU B 2 101 ? 86.385  89.554  73.353  1.00 190.41 ? 101 LEU B C   1 
ATOM   4054  O  O   . LEU B 2 101 ? 86.154  89.487  72.143  1.00 210.24 ? 101 LEU B O   1 
ATOM   4055  C  CB  . LEU B 2 101 ? 86.131  87.275  74.397  1.00 167.09 ? 101 LEU B CB  1 
ATOM   4056  C  CG  . LEU B 2 101 ? 86.781  85.913  74.217  1.00 188.15 ? 101 LEU B CG  1 
ATOM   4057  C  CD1 . LEU B 2 101 ? 85.900  84.825  74.811  1.00 315.37 ? 101 LEU B CD1 1 
ATOM   4058  C  CD2 . LEU B 2 101 ? 87.046  85.633  72.736  1.00 231.77 ? 101 LEU B CD2 1 
ATOM   4059  N  N   . CYS B 2 102 ? 86.047  90.619  74.077  1.00 144.77 ? 102 CYS B N   1 
ATOM   4060  C  CA  . CYS B 2 102 ? 85.533  91.818  73.435  1.00 178.32 ? 102 CYS B CA  1 
ATOM   4061  C  C   . CYS B 2 102 ? 86.640  92.623  72.737  1.00 187.02 ? 102 CYS B C   1 
ATOM   4062  O  O   . CYS B 2 102 ? 86.409  93.228  71.688  1.00 219.06 ? 102 CYS B O   1 
ATOM   4063  C  CB  . CYS B 2 102 ? 84.743  92.609  74.466  1.00 169.55 ? 102 CYS B CB  1 
ATOM   4064  S  SG  . CYS B 2 102 ? 83.497  91.542  75.253  1.00 197.39 ? 102 CYS B SG  1 
ATOM   4065  N  N   . TYR B 2 103 ? 87.844  92.642  73.310  1.00 174.15 ? 103 TYR B N   1 
ATOM   4066  C  CA  . TYR B 2 103 ? 88.982  93.288  72.674  1.00 179.74 ? 103 TYR B CA  1 
ATOM   4067  C  C   . TYR B 2 103 ? 89.530  92.450  71.516  1.00 217.27 ? 103 TYR B C   1 
ATOM   4068  O  O   . TYR B 2 103 ? 90.076  93.005  70.568  1.00 269.55 ? 103 TYR B O   1 
ATOM   4069  C  CB  . TYR B 2 103 ? 90.076  93.543  73.707  1.00 156.38 ? 103 TYR B CB  1 
ATOM   4070  C  CG  . TYR B 2 103 ? 89.824  94.848  74.434  1.00 190.57 ? 103 TYR B CG  1 
ATOM   4071  C  CD1 . TYR B 2 103 ? 88.663  95.023  75.171  1.00 206.90 ? 103 TYR B CD1 1 
ATOM   4072  C  CD2 . TYR B 2 103 ? 90.739  95.897  74.388  1.00 174.46 ? 103 TYR B CD2 1 
ATOM   4073  C  CE1 . TYR B 2 103 ? 88.426  96.208  75.843  1.00 207.03 ? 103 TYR B CE1 1 
ATOM   4074  C  CE2 . TYR B 2 103 ? 90.515  97.087  75.055  1.00 155.24 ? 103 TYR B CE2 1 
ATOM   4075  C  CZ  . TYR B 2 103 ? 89.351  97.235  75.783  1.00 178.32 ? 103 TYR B CZ  1 
ATOM   4076  O  OH  . TYR B 2 103 ? 89.105  98.392  76.433  1.00 164.66 ? 103 TYR B OH  1 
ATOM   4077  N  N   . ALA B 2 104 ? 89.408  91.119  71.602  1.00 191.89 ? 104 ALA B N   1 
ATOM   4078  C  CA  . ALA B 2 104 ? 89.689  90.208  70.502  1.00 184.98 ? 104 ALA B CA  1 
ATOM   4079  C  C   . ALA B 2 104 ? 88.761  90.461  69.321  1.00 162.21 ? 104 ALA B C   1 
ATOM   4080  O  O   . ALA B 2 104 ? 89.193  90.266  68.179  1.00 167.76 ? 104 ALA B O   1 
ATOM   4081  C  CB  . ALA B 2 104 ? 89.547  88.801  71.025  1.00 265.02 ? 104 ALA B CB  1 
ATOM   4082  N  N   . GLU B 2 105 ? 87.502  90.876  69.603  1.00 168.97 ? 105 GLU B N   1 
ATOM   4083  C  CA  . GLU B 2 105 ? 86.653  91.425  68.557  1.00 216.33 ? 105 GLU B CA  1 
ATOM   4084  C  C   . GLU B 2 105 ? 87.207  92.780  68.106  1.00 168.54 ? 105 GLU B C   1 
ATOM   4085  O  O   . GLU B 2 105 ? 87.683  92.860  66.969  1.00 164.77 ? 105 GLU B O   1 
ATOM   4086  C  CB  . GLU B 2 105 ? 85.183  91.513  68.970  1.00 246.15 ? 105 GLU B CB  1 
ATOM   4087  C  CG  . GLU B 2 105 ? 84.299  92.025  67.824  1.00 318.58 ? 105 GLU B CG  1 
ATOM   4088  C  CD  . GLU B 2 105 ? 82.820  91.677  67.877  1.00 396.49 ? 105 GLU B CD  1 
ATOM   4089  O  OE1 . GLU B 2 105 ? 82.495  90.532  68.231  1.00 459.89 ? 105 GLU B OE1 1 
ATOM   4090  O  OE2 . GLU B 2 105 ? 81.979  92.546  67.547  1.00 418.35 ? 105 GLU B OE2 1 
ATOM   4091  N  N   . LEU B 2 106 ? 87.154  93.807  68.976  1.00 152.87 ? 106 LEU B N   1 
ATOM   4092  C  CA  . LEU B 2 106 ? 87.410  95.197  68.586  1.00 162.17 ? 106 LEU B CA  1 
ATOM   4093  C  C   . LEU B 2 106 ? 88.650  95.320  67.706  1.00 184.13 ? 106 LEU B C   1 
ATOM   4094  O  O   . LEU B 2 106 ? 88.562  95.931  66.645  1.00 209.64 ? 106 LEU B O   1 
ATOM   4095  C  CB  . LEU B 2 106 ? 87.586  96.096  69.814  1.00 203.03 ? 106 LEU B CB  1 
ATOM   4096  C  CG  . LEU B 2 106 ? 86.316  96.748  70.349  1.00 255.46 ? 106 LEU B CG  1 
ATOM   4097  C  CD1 . LEU B 2 106 ? 86.610  97.374  71.697  1.00 259.19 ? 106 LEU B CD1 1 
ATOM   4098  C  CD2 . LEU B 2 106 ? 85.745  97.791  69.386  1.00 233.09 ? 106 LEU B CD2 1 
ATOM   4099  N  N   . GLY B 2 107 ? 89.783  94.742  68.131  1.00 202.55 ? 107 GLY B N   1 
ATOM   4100  C  CA  . GLY B 2 107 ? 91.038  94.908  67.408  1.00 240.86 ? 107 GLY B CA  1 
ATOM   4101  C  C   . GLY B 2 107 ? 91.117  94.208  66.049  1.00 248.10 ? 107 GLY B C   1 
ATOM   4102  O  O   . GLY B 2 107 ? 92.048  94.457  65.291  1.00 274.02 ? 107 GLY B O   1 
ATOM   4103  N  N   . THR B 2 108 ? 90.159  93.335  65.719  1.00 219.44 ? 108 THR B N   1 
ATOM   4104  C  CA  . THR B 2 108 ? 90.011  92.850  64.352  1.00 200.35 ? 108 THR B CA  1 
ATOM   4105  C  C   . THR B 2 108 ? 89.064  93.748  63.549  1.00 185.53 ? 108 THR B C   1 
ATOM   4106  O  O   . THR B 2 108 ? 89.188  93.795  62.330  1.00 236.26 ? 108 THR B O   1 
ATOM   4107  C  CB  . THR B 2 108 ? 89.582  91.379  64.326  1.00 193.30 ? 108 THR B CB  1 
ATOM   4108  O  OG1 . THR B 2 108 ? 88.273  91.260  64.903  1.00 156.17 ? 108 THR B OG1 1 
ATOM   4109  C  CG2 . THR B 2 108 ? 90.605  90.501  65.022  1.00 179.60 ? 108 THR B CG2 1 
ATOM   4110  N  N   . THR B 2 109 ? 88.128  94.454  64.196  1.00 159.68 ? 109 THR B N   1 
ATOM   4111  C  CA  . THR B 2 109 ? 87.262  95.415  63.511  1.00 191.31 ? 109 THR B CA  1 
ATOM   4112  C  C   . THR B 2 109 ? 88.000  96.720  63.184  1.00 189.23 ? 109 THR B C   1 
ATOM   4113  O  O   . THR B 2 109 ? 87.738  97.328  62.144  1.00 220.36 ? 109 THR B O   1 
ATOM   4114  C  CB  . THR B 2 109 ? 85.997  95.743  64.323  1.00 228.92 ? 109 THR B CB  1 
ATOM   4115  O  OG1 . THR B 2 109 ? 86.293  96.699  65.346  1.00 194.86 ? 109 THR B OG1 1 
ATOM   4116  C  CG2 . THR B 2 109 ? 85.361  94.522  64.959  1.00 256.04 ? 109 THR B CG2 1 
ATOM   4117  N  N   . ILE B 2 110 ? 88.899  97.153  64.080  1.00 205.62 ? 110 ILE B N   1 
ATOM   4118  C  CA  . ILE B 2 110 ? 89.695  98.362  63.930  1.00 227.74 ? 110 ILE B CA  1 
ATOM   4119  C  C   . ILE B 2 110 ? 91.171  97.989  64.107  1.00 229.31 ? 110 ILE B C   1 
ATOM   4120  O  O   . ILE B 2 110 ? 91.597  97.712  65.226  1.00 268.13 ? 110 ILE B O   1 
ATOM   4121  C  CB  . ILE B 2 110 ? 89.217  99.411  64.963  1.00 222.02 ? 110 ILE B CB  1 
ATOM   4122  C  CG1 . ILE B 2 110 ? 87.747  99.803  64.773  1.00 226.94 ? 110 ILE B CG1 1 
ATOM   4123  C  CG2 . ILE B 2 110 ? 90.110  100.638 64.942  1.00 226.12 ? 110 ILE B CG2 1 
ATOM   4124  C  CD1 . ILE B 2 110 ? 87.127  100.462 65.982  1.00 261.83 ? 110 ILE B CD1 1 
ATOM   4125  N  N   . SER B 2 111 ? 91.956  97.994  63.021  1.00 224.06 ? 111 SER B N   1 
ATOM   4126  C  CA  . SER B 2 111 ? 93.322  97.481  63.043  1.00 249.62 ? 111 SER B CA  1 
ATOM   4127  C  C   . SER B 2 111 ? 94.372  98.485  63.552  1.00 272.46 ? 111 SER B C   1 
ATOM   4128  O  O   . SER B 2 111 ? 95.563  98.146  63.553  1.00 349.54 ? 111 SER B O   1 
ATOM   4129  C  CB  . SER B 2 111 ? 93.687  96.987  61.668  1.00 321.72 ? 111 SER B CB  1 
ATOM   4130  O  OG  . SER B 2 111 ? 93.543  98.019  60.701  1.00 385.00 ? 111 SER B OG  1 
ATOM   4131  N  N   . LYS B 2 112 ? 93.982  99.701  63.990  1.00 259.54 ? 112 LYS B N   1 
ATOM   4132  C  CA  . LYS B 2 112 ? 94.933  100.688 64.509  1.00 249.26 ? 112 LYS B CA  1 
ATOM   4133  C  C   . LYS B 2 112 ? 95.606  100.266 65.830  1.00 230.26 ? 112 LYS B C   1 
ATOM   4134  O  O   . LYS B 2 112 ? 94.961  99.714  66.724  1.00 194.16 ? 112 LYS B O   1 
ATOM   4135  C  CB  . LYS B 2 112 ? 94.239  102.033 64.749  1.00 254.23 ? 112 LYS B CB  1 
ATOM   4136  C  CG  . LYS B 2 112 ? 93.806  102.773 63.500  1.00 249.13 ? 112 LYS B CG  1 
ATOM   4137  C  CD  . LYS B 2 112 ? 93.046  104.037 63.846  1.00 288.41 ? 112 LYS B CD  1 
ATOM   4138  C  CE  . LYS B 2 112 ? 92.858  104.967 62.667  1.00 399.30 ? 112 LYS B CE  1 
ATOM   4139  N  NZ  . LYS B 2 112 ? 91.891  104.416 61.683  1.00 428.35 ? 112 LYS B NZ  1 
ATOM   4140  N  N   . SER B 2 113 ? 96.915  100.571 65.948  1.00 220.88 ? 113 SER B N   1 
ATOM   4141  C  CA  . SER B 2 113 ? 97.715  100.281 67.134  1.00 224.94 ? 113 SER B CA  1 
ATOM   4142  C  C   . SER B 2 113 ? 97.424  101.236 68.296  1.00 215.87 ? 113 SER B C   1 
ATOM   4143  O  O   . SER B 2 113 ? 98.105  101.149 69.313  1.00 193.17 ? 113 SER B O   1 
ATOM   4144  C  CB  . SER B 2 113 ? 99.226  100.289 66.852  1.00 267.58 ? 113 SER B CB  1 
ATOM   4145  O  OG  . SER B 2 113 ? 99.648  101.422 66.093  1.00 398.20 ? 113 SER B OG  1 
ATOM   4146  N  N   . GLY B 2 114 ? 96.449  102.146 68.219  1.00 208.34 ? 114 GLY B N   1 
ATOM   4147  C  CA  . GLY B 2 114 ? 96.102  102.926 69.399  1.00 211.30 ? 114 GLY B CA  1 
ATOM   4148  C  C   . GLY B 2 114 ? 95.418  102.131 70.513  1.00 185.26 ? 114 GLY B C   1 
ATOM   4149  O  O   . GLY B 2 114 ? 95.212  102.679 71.593  1.00 172.78 ? 114 GLY B O   1 
ATOM   4150  N  N   . GLY B 2 115 ? 95.029  100.877 70.243  1.00 176.07 ? 115 GLY B N   1 
ATOM   4151  C  CA  . GLY B 2 115 ? 94.346  100.015 71.186  1.00 178.44 ? 115 GLY B CA  1 
ATOM   4152  C  C   . GLY B 2 115 ? 93.170  100.702 71.853  1.00 206.36 ? 115 GLY B C   1 
ATOM   4153  O  O   . GLY B 2 115 ? 92.293  101.229 71.197  1.00 205.74 ? 115 GLY B O   1 
ATOM   4154  N  N   . ASP B 2 116 ? 93.191  100.704 73.173  1.00 201.42 ? 116 ASP B N   1 
ATOM   4155  C  CA  . ASP B 2 116 ? 92.121  101.209 74.006  1.00 195.34 ? 116 ASP B CA  1 
ATOM   4156  C  C   . ASP B 2 116 ? 91.738  102.663 73.670  1.00 157.51 ? 116 ASP B C   1 
ATOM   4157  O  O   . ASP B 2 116 ? 90.599  103.058 73.950  1.00 145.24 ? 116 ASP B O   1 
ATOM   4158  C  CB  . ASP B 2 116 ? 92.640  101.010 75.439  1.00 276.95 ? 116 ASP B CB  1 
ATOM   4159  C  CG  . ASP B 2 116 ? 91.613  100.943 76.548  1.00 267.12 ? 116 ASP B CG  1 
ATOM   4160  O  OD1 . ASP B 2 116 ? 90.565  100.361 76.310  1.00 223.88 ? 116 ASP B OD1 1 
ATOM   4161  O  OD2 . ASP B 2 116 ? 91.891  101.459 77.651  1.00 227.88 ? 116 ASP B OD2 1 
ATOM   4162  N  N   . TYR B 2 117 ? 92.703  103.454 73.133  1.00 165.06 ? 117 TYR B N   1 
ATOM   4163  C  CA  . TYR B 2 117 ? 92.584  104.870 72.788  1.00 161.93 ? 117 TYR B CA  1 
ATOM   4164  C  C   . TYR B 2 117 ? 91.966  104.996 71.401  1.00 137.03 ? 117 TYR B C   1 
ATOM   4165  O  O   . TYR B 2 117 ? 91.034  105.778 71.240  1.00 134.38 ? 117 TYR B O   1 
ATOM   4166  C  CB  . TYR B 2 117 ? 93.943  105.592 72.902  1.00 177.20 ? 117 TYR B CB  1 
ATOM   4167  C  CG  . TYR B 2 117 ? 94.143  106.837 72.038  1.00 193.81 ? 117 TYR B CG  1 
ATOM   4168  C  CD1 . TYR B 2 117 ? 93.705  108.084 72.468  1.00 208.93 ? 117 TYR B CD1 1 
ATOM   4169  C  CD2 . TYR B 2 117 ? 94.755  106.776 70.785  1.00 164.63 ? 117 TYR B CD2 1 
ATOM   4170  C  CE1 . TYR B 2 117 ? 93.874  109.225 71.698  1.00 181.59 ? 117 TYR B CE1 1 
ATOM   4171  C  CE2 . TYR B 2 117 ? 94.935  107.914 70.016  1.00 149.08 ? 117 TYR B CE2 1 
ATOM   4172  C  CZ  . TYR B 2 117 ? 94.496  109.144 70.468  1.00 185.74 ? 117 TYR B CZ  1 
ATOM   4173  O  OH  . TYR B 2 117 ? 94.651  110.289 69.718  1.00 293.05 ? 117 TYR B OH  1 
ATOM   4174  N  N   . ALA B 2 118 ? 92.485  104.244 70.422  1.00 136.62 ? 118 ALA B N   1 
ATOM   4175  C  CA  . ALA B 2 118 ? 91.957  104.255 69.068  1.00 156.21 ? 118 ALA B CA  1 
ATOM   4176  C  C   . ALA B 2 118 ? 90.483  103.856 69.059  1.00 188.57 ? 118 ALA B C   1 
ATOM   4177  O  O   . ALA B 2 118 ? 89.695  104.485 68.351  1.00 260.08 ? 118 ALA B O   1 
ATOM   4178  C  CB  . ALA B 2 118 ? 92.728  103.349 68.149  1.00 156.08 ? 118 ALA B CB  1 
ATOM   4179  N  N   . TYR B 2 119 ? 90.104  102.833 69.833  1.00 149.09 ? 119 TYR B N   1 
ATOM   4180  C  CA  . TYR B 2 119 ? 88.713  102.384 69.869  1.00 203.37 ? 119 TYR B CA  1 
ATOM   4181  C  C   . TYR B 2 119 ? 87.781  103.466 70.417  1.00 200.83 ? 119 TYR B C   1 
ATOM   4182  O  O   . TYR B 2 119 ? 86.595  103.443 70.097  1.00 263.95 ? 119 TYR B O   1 
ATOM   4183  C  CB  . TYR B 2 119 ? 88.519  101.060 70.624  1.00 207.04 ? 119 TYR B CB  1 
ATOM   4184  C  CG  . TYR B 2 119 ? 89.511  99.998  70.180  1.00 208.39 ? 119 TYR B CG  1 
ATOM   4185  C  CD1 . TYR B 2 119 ? 89.989  99.925  68.859  1.00 183.99 ? 119 TYR B CD1 1 
ATOM   4186  C  CD2 . TYR B 2 119 ? 89.977  99.070  71.100  1.00 222.68 ? 119 TYR B CD2 1 
ATOM   4187  C  CE1 . TYR B 2 119 ? 90.905  98.954  68.484  1.00 247.68 ? 119 TYR B CE1 1 
ATOM   4188  C  CE2 . TYR B 2 119 ? 90.889  98.098  70.727  1.00 243.24 ? 119 TYR B CE2 1 
ATOM   4189  C  CZ  . TYR B 2 119 ? 91.357  98.040  69.423  1.00 251.91 ? 119 TYR B CZ  1 
ATOM   4190  O  OH  . TYR B 2 119 ? 92.263  97.084  69.062  1.00 200.52 ? 119 TYR B OH  1 
ATOM   4191  N  N   . MET B 2 120 ? 88.291  104.410 71.223  1.00 192.38 ? 120 MET B N   1 
ATOM   4192  C  CA  . MET B 2 120 ? 87.496  105.550 71.658  1.00 222.82 ? 120 MET B CA  1 
ATOM   4193  C  C   . MET B 2 120 ? 87.464  106.582 70.540  1.00 179.59 ? 120 MET B C   1 
ATOM   4194  O  O   . MET B 2 120 ? 86.394  107.104 70.261  1.00 280.42 ? 120 MET B O   1 
ATOM   4195  C  CB  . MET B 2 120 ? 87.988  106.125 72.997  1.00 204.58 ? 120 MET B CB  1 
ATOM   4196  C  CG  . MET B 2 120 ? 87.595  105.118 74.124  1.00 197.87 ? 120 MET B CG  1 
ATOM   4197  S  SD  . MET B 2 120 ? 88.007  105.458 75.822  1.00 225.00 ? 120 MET B SD  1 
ATOM   4198  C  CE  . MET B 2 120 ? 87.085  106.976 76.059  1.00 280.35 ? 120 MET B CE  1 
ATOM   4199  N  N   . LEU B 2 121 ? 88.593  106.847 69.903  1.00 135.77 ? 121 LEU B N   1 
ATOM   4200  C  CA  . LEU B 2 121 ? 88.665  107.846 68.848  1.00 222.62 ? 121 LEU B CA  1 
ATOM   4201  C  C   . LEU B 2 121 ? 87.711  107.524 67.684  1.00 260.72 ? 121 LEU B C   1 
ATOM   4202  O  O   . LEU B 2 121 ? 87.054  108.429 67.157  1.00 291.21 ? 121 LEU B O   1 
ATOM   4203  C  CB  . LEU B 2 121 ? 90.131  107.931 68.407  1.00 230.22 ? 121 LEU B CB  1 
ATOM   4204  C  CG  . LEU B 2 121 ? 90.436  108.953 67.325  1.00 241.08 ? 121 LEU B CG  1 
ATOM   4205  C  CD1 . LEU B 2 121 ? 90.120  110.372 67.824  1.00 226.12 ? 121 LEU B CD1 1 
ATOM   4206  C  CD2 . LEU B 2 121 ? 91.874  108.777 66.872  1.00 259.90 ? 121 LEU B CD2 1 
ATOM   4207  N  N   . GLU B 2 122 ? 87.620  106.241 67.301  1.00 252.14 ? 122 GLU B N   1 
ATOM   4208  C  CA  . GLU B 2 122 ? 86.764  105.787 66.209  1.00 276.87 ? 122 GLU B CA  1 
ATOM   4209  C  C   . GLU B 2 122 ? 85.277  105.753 66.569  1.00 225.73 ? 122 GLU B C   1 
ATOM   4210  O  O   . GLU B 2 122 ? 84.477  105.377 65.710  1.00 262.74 ? 122 GLU B O   1 
ATOM   4211  C  CB  . GLU B 2 122 ? 87.210  104.396 65.752  1.00 294.59 ? 122 GLU B CB  1 
ATOM   4212  C  CG  . GLU B 2 122 ? 88.508  104.424 64.960  1.00 381.09 ? 122 GLU B CG  1 
ATOM   4213  C  CD  . GLU B 2 122 ? 88.405  104.746 63.475  1.00 454.71 ? 122 GLU B CD  1 
ATOM   4214  O  OE1 . GLU B 2 122 ? 87.389  105.338 63.053  1.00 509.63 ? 122 GLU B OE1 1 
ATOM   4215  O  OE2 . GLU B 2 122 ? 89.343  104.393 62.737  1.00 506.50 ? 122 GLU B OE2 1 
ATOM   4216  N  N   . VAL B 2 123 ? 84.903  106.142 67.797  1.00 198.11 ? 123 VAL B N   1 
ATOM   4217  C  CA  . VAL B 2 123 ? 83.515  106.149 68.239  1.00 248.95 ? 123 VAL B CA  1 
ATOM   4218  C  C   . VAL B 2 123 ? 83.146  107.544 68.753  1.00 242.55 ? 123 VAL B C   1 
ATOM   4219  O  O   . VAL B 2 123 ? 82.329  108.230 68.132  1.00 288.16 ? 123 VAL B O   1 
ATOM   4220  C  CB  . VAL B 2 123 ? 83.262  105.033 69.286  1.00 232.07 ? 123 VAL B CB  1 
ATOM   4221  C  CG1 . VAL B 2 123 ? 81.878  105.116 69.897  1.00 211.19 ? 123 VAL B CG1 1 
ATOM   4222  C  CG2 . VAL B 2 123 ? 83.482  103.638 68.691  1.00 214.52 ? 123 VAL B CG2 1 
ATOM   4223  N  N   . TYR B 2 124 ? 83.744  107.935 69.887  1.00 218.37 ? 124 TYR B N   1 
ATOM   4224  C  CA  . TYR B 2 124 ? 83.388  109.140 70.629  1.00 239.52 ? 124 TYR B CA  1 
ATOM   4225  C  C   . TYR B 2 124 ? 84.089  110.394 70.106  1.00 215.50 ? 124 TYR B C   1 
ATOM   4226  O  O   . TYR B 2 124 ? 83.787  111.489 70.585  1.00 192.37 ? 124 TYR B O   1 
ATOM   4227  C  CB  . TYR B 2 124 ? 83.755  108.947 72.099  1.00 222.84 ? 124 TYR B CB  1 
ATOM   4228  C  CG  . TYR B 2 124 ? 83.135  107.691 72.678  1.00 203.11 ? 124 TYR B CG  1 
ATOM   4229  C  CD1 . TYR B 2 124 ? 81.793  107.650 73.018  1.00 238.81 ? 124 TYR B CD1 1 
ATOM   4230  C  CD2 . TYR B 2 124 ? 83.894  106.549 72.871  1.00 261.81 ? 124 TYR B CD2 1 
ATOM   4231  C  CE1 . TYR B 2 124 ? 81.219  106.505 73.545  1.00 258.28 ? 124 TYR B CE1 1 
ATOM   4232  C  CE2 . TYR B 2 124 ? 83.335  105.397 73.395  1.00 269.48 ? 124 TYR B CE2 1 
ATOM   4233  C  CZ  . TYR B 2 124 ? 81.994  105.377 73.733  1.00 232.85 ? 124 TYR B CZ  1 
ATOM   4234  O  OH  . TYR B 2 124 ? 81.441  104.253 74.251  1.00 214.64 ? 124 TYR B OH  1 
ATOM   4235  N  N   . GLY B 2 125 ? 85.006  110.233 69.140  1.00 205.26 ? 125 GLY B N   1 
ATOM   4236  C  CA  . GLY B 2 125 ? 85.648  111.354 68.478  1.00 236.47 ? 125 GLY B CA  1 
ATOM   4237  C  C   . GLY B 2 125 ? 86.740  112.004 69.331  1.00 204.01 ? 125 GLY B C   1 
ATOM   4238  O  O   . GLY B 2 125 ? 87.178  111.455 70.342  1.00 139.42 ? 125 GLY B O   1 
ATOM   4239  N  N   . SER B 2 126 ? 87.145  113.207 68.897  1.00 241.26 ? 126 SER B N   1 
ATOM   4240  C  CA  . SER B 2 126 ? 88.434  113.802 69.215  1.00 228.20 ? 126 SER B CA  1 
ATOM   4241  C  C   . SER B 2 126 ? 88.617  113.991 70.717  1.00 227.95 ? 126 SER B C   1 
ATOM   4242  O  O   . SER B 2 126 ? 89.573  113.445 71.272  1.00 331.58 ? 126 SER B O   1 
ATOM   4243  C  CB  . SER B 2 126 ? 88.608  115.115 68.495  1.00 244.08 ? 126 SER B CB  1 
ATOM   4244  O  OG  . SER B 2 126 ? 89.877  115.685 68.779  1.00 249.93 ? 126 SER B OG  1 
ATOM   4245  N  N   . LEU B 2 127 ? 87.721  114.747 71.370  1.00 167.78 ? 127 LEU B N   1 
ATOM   4246  C  CA  . LEU B 2 127 ? 87.994  115.155 72.743  1.00 189.04 ? 127 LEU B CA  1 
ATOM   4247  C  C   . LEU B 2 127 ? 87.970  113.964 73.722  1.00 264.49 ? 127 LEU B C   1 
ATOM   4248  O  O   . LEU B 2 127 ? 88.926  113.824 74.490  1.00 302.88 ? 127 LEU B O   1 
ATOM   4249  C  CB  . LEU B 2 127 ? 87.055  116.289 73.173  1.00 202.02 ? 127 LEU B CB  1 
ATOM   4250  C  CG  . LEU B 2 127 ? 87.062  116.586 74.676  1.00 242.13 ? 127 LEU B CG  1 
ATOM   4251  C  CD1 . LEU B 2 127 ? 88.405  117.159 75.111  1.00 190.93 ? 127 LEU B CD1 1 
ATOM   4252  C  CD2 . LEU B 2 127 ? 85.931  117.526 75.069  1.00 300.37 ? 127 LEU B CD2 1 
ATOM   4253  N  N   . PRO B 2 128 ? 86.936  113.081 73.786  1.00 258.36 ? 128 PRO B N   1 
ATOM   4254  C  CA  . PRO B 2 128 ? 86.973  111.917 74.690  1.00 286.48 ? 128 PRO B CA  1 
ATOM   4255  C  C   . PRO B 2 128 ? 88.222  111.033 74.594  1.00 223.35 ? 128 PRO B C   1 
ATOM   4256  O  O   . PRO B 2 128 ? 88.720  110.555 75.609  1.00 157.45 ? 128 PRO B O   1 
ATOM   4257  C  CB  . PRO B 2 128 ? 85.710  111.144 74.280  1.00 277.73 ? 128 PRO B CB  1 
ATOM   4258  C  CG  . PRO B 2 128 ? 84.778  112.237 73.856  1.00 252.35 ? 128 PRO B CG  1 
ATOM   4259  C  CD  . PRO B 2 128 ? 85.668  113.147 73.043  1.00 212.37 ? 128 PRO B CD  1 
ATOM   4260  N  N   . ALA B 2 129 ? 88.737  110.836 73.381  1.00 187.07 ? 129 ALA B N   1 
ATOM   4261  C  CA  . ALA B 2 129 ? 89.979  110.105 73.213  1.00 198.51 ? 129 ALA B CA  1 
ATOM   4262  C  C   . ALA B 2 129 ? 91.162  110.878 73.822  1.00 207.85 ? 129 ALA B C   1 
ATOM   4263  O  O   . ALA B 2 129 ? 92.025  110.258 74.424  1.00 265.96 ? 129 ALA B O   1 
ATOM   4264  C  CB  . ALA B 2 129 ? 90.203  109.791 71.748  1.00 174.86 ? 129 ALA B CB  1 
ATOM   4265  N  N   . PHE B 2 130 ? 91.222  112.211 73.673  1.00 166.72 ? 130 PHE B N   1 
ATOM   4266  C  CA  . PHE B 2 130 ? 92.312  113.000 74.220  1.00 158.42 ? 130 PHE B CA  1 
ATOM   4267  C  C   . PHE B 2 130 ? 92.320  112.930 75.740  1.00 161.66 ? 130 PHE B C   1 
ATOM   4268  O  O   . PHE B 2 130 ? 93.379  112.779 76.338  1.00 206.36 ? 130 PHE B O   1 
ATOM   4269  C  CB  . PHE B 2 130 ? 92.243  114.467 73.791  1.00 142.24 ? 130 PHE B CB  1 
ATOM   4270  C  CG  . PHE B 2 130 ? 93.401  115.268 74.320  1.00 194.84 ? 130 PHE B CG  1 
ATOM   4271  C  CD1 . PHE B 2 130 ? 93.329  115.870 75.582  1.00 208.21 ? 130 PHE B CD1 1 
ATOM   4272  C  CD2 . PHE B 2 130 ? 94.574  115.407 73.574  1.00 177.09 ? 130 PHE B CD2 1 
ATOM   4273  C  CE1 . PHE B 2 130 ? 94.402  116.607 76.075  1.00 229.19 ? 130 PHE B CE1 1 
ATOM   4274  C  CE2 . PHE B 2 130 ? 95.648  116.138 74.073  1.00 199.79 ? 130 PHE B CE2 1 
ATOM   4275  C  CZ  . PHE B 2 130 ? 95.561  116.739 75.323  1.00 222.55 ? 130 PHE B CZ  1 
ATOM   4276  N  N   . LEU B 2 131 ? 91.157  113.055 76.362  1.00 181.07 ? 131 LEU B N   1 
ATOM   4277  C  CA  . LEU B 2 131 ? 91.113  113.037 77.813  1.00 247.59 ? 131 LEU B CA  1 
ATOM   4278  C  C   . LEU B 2 131 ? 91.675  111.728 78.373  1.00 275.58 ? 131 LEU B C   1 
ATOM   4279  O  O   . LEU B 2 131 ? 92.202  111.741 79.484  1.00 259.45 ? 131 LEU B O   1 
ATOM   4280  C  CB  . LEU B 2 131 ? 89.662  113.254 78.252  1.00 307.77 ? 131 LEU B CB  1 
ATOM   4281  C  CG  . LEU B 2 131 ? 89.108  114.652 78.000  1.00 345.10 ? 131 LEU B CG  1 
ATOM   4282  C  CD1 . LEU B 2 131 ? 87.636  114.723 78.382  1.00 418.32 ? 131 LEU B CD1 1 
ATOM   4283  C  CD2 . LEU B 2 131 ? 89.915  115.682 78.774  1.00 319.48 ? 131 LEU B CD2 1 
ATOM   4284  N  N   . LYS B 2 132 ? 91.563  110.618 77.620  1.00 247.83 ? 132 LYS B N   1 
ATOM   4285  C  CA  . LYS B 2 132 ? 92.223  109.373 77.979  1.00 217.10 ? 132 LYS B CA  1 
ATOM   4286  C  C   . LYS B 2 132 ? 93.732  109.521 77.851  1.00 191.59 ? 132 LYS B C   1 
ATOM   4287  O  O   . LYS B 2 132 ? 94.467  109.267 78.809  1.00 181.66 ? 132 LYS B O   1 
ATOM   4288  C  CB  . LYS B 2 132 ? 91.775  108.209 77.095  1.00 175.70 ? 132 LYS B CB  1 
ATOM   4289  C  CG  . LYS B 2 132 ? 92.344  106.868 77.510  1.00 193.84 ? 132 LYS B CG  1 
ATOM   4290  C  CD  . LYS B 2 132 ? 91.958  105.772 76.585  1.00 181.56 ? 132 LYS B CD  1 
ATOM   4291  C  CE  . LYS B 2 132 ? 91.950  104.421 77.263  1.00 212.85 ? 132 LYS B CE  1 
ATOM   4292  N  NZ  . LYS B 2 132 ? 93.308  103.898 77.562  1.00 205.77 ? 132 LYS B NZ  1 
ATOM   4293  N  N   . LEU B 2 133 ? 94.173  109.920 76.655  1.00 172.09 ? 133 LEU B N   1 
ATOM   4294  C  CA  . LEU B 2 133 ? 95.587  109.942 76.333  1.00 170.77 ? 133 LEU B CA  1 
ATOM   4295  C  C   . LEU B 2 133 ? 96.358  110.855 77.291  1.00 177.82 ? 133 LEU B C   1 
ATOM   4296  O  O   . LEU B 2 133 ? 97.472  110.518 77.659  1.00 191.73 ? 133 LEU B O   1 
ATOM   4297  C  CB  . LEU B 2 133 ? 95.720  110.418 74.897  1.00 165.27 ? 133 LEU B CB  1 
ATOM   4298  C  CG  . LEU B 2 133 ? 97.120  110.378 74.319  1.00 201.93 ? 133 LEU B CG  1 
ATOM   4299  C  CD1 . LEU B 2 133 ? 97.488  108.957 73.965  1.00 200.30 ? 133 LEU B CD1 1 
ATOM   4300  C  CD2 . LEU B 2 133 ? 97.203  111.304 73.120  1.00 255.89 ? 133 LEU B CD2 1 
ATOM   4301  N  N   . TRP B 2 134 ? 95.764  111.986 77.697  1.00 148.39 ? 134 TRP B N   1 
ATOM   4302  C  CA  . TRP B 2 134 ? 96.356  112.888 78.663  1.00 178.08 ? 134 TRP B CA  1 
ATOM   4303  C  C   . TRP B 2 134 ? 96.650  112.181 79.996  1.00 217.37 ? 134 TRP B C   1 
ATOM   4304  O  O   . TRP B 2 134 ? 97.752  112.296 80.534  1.00 230.21 ? 134 TRP B O   1 
ATOM   4305  C  CB  . TRP B 2 134 ? 95.446  114.116 78.840  1.00 197.24 ? 134 TRP B CB  1 
ATOM   4306  C  CG  . TRP B 2 134 ? 96.046  115.127 79.782  1.00 212.70 ? 134 TRP B CG  1 
ATOM   4307  C  CD1 . TRP B 2 134 ? 95.535  115.537 80.980  1.00 169.49 ? 134 TRP B CD1 1 
ATOM   4308  C  CD2 . TRP B 2 134 ? 97.301  115.832 79.607  1.00 172.66 ? 134 TRP B CD2 1 
ATOM   4309  N  NE1 . TRP B 2 134 ? 96.375  116.450 81.548  1.00 170.97 ? 134 TRP B NE1 1 
ATOM   4310  C  CE2 . TRP B 2 134 ? 97.466  116.654 80.742  1.00 177.47 ? 134 TRP B CE2 1 
ATOM   4311  C  CE3 . TRP B 2 134 ? 98.296  115.851 78.616  1.00 226.30 ? 134 TRP B CE3 1 
ATOM   4312  C  CZ2 . TRP B 2 134 ? 98.582  117.481 80.913  1.00 237.78 ? 134 TRP B CZ2 1 
ATOM   4313  C  CZ3 . TRP B 2 134 ? 99.400  116.667 78.784  1.00 258.23 ? 134 TRP B CZ3 1 
ATOM   4314  C  CH2 . TRP B 2 134 ? 99.542  117.472 79.920  1.00 240.12 ? 134 TRP B CH2 1 
ATOM   4315  N  N   . ILE B 2 135 ? 95.686  111.437 80.535  1.00 176.68 ? 135 ILE B N   1 
ATOM   4316  C  CA  . ILE B 2 135 ? 95.862  110.754 81.817  1.00 177.80 ? 135 ILE B CA  1 
ATOM   4317  C  C   . ILE B 2 135 ? 96.883  109.624 81.709  1.00 184.85 ? 135 ILE B C   1 
ATOM   4318  O  O   . ILE B 2 135 ? 97.685  109.448 82.618  1.00 175.96 ? 135 ILE B O   1 
ATOM   4319  C  CB  . ILE B 2 135 ? 94.481  110.290 82.323  1.00 199.76 ? 135 ILE B CB  1 
ATOM   4320  C  CG1 . ILE B 2 135 ? 93.671  111.515 82.750  1.00 316.51 ? 135 ILE B CG1 1 
ATOM   4321  C  CG2 . ILE B 2 135 ? 94.549  109.260 83.444  1.00 199.09 ? 135 ILE B CG2 1 
ATOM   4322  C  CD1 . ILE B 2 135 ? 94.291  112.327 83.898  1.00 386.34 ? 135 ILE B CD1 1 
ATOM   4323  N  N   . GLU B 2 136 ? 96.839  108.872 80.603  1.00 189.83 ? 136 GLU B N   1 
ATOM   4324  C  CA  . GLU B 2 136 ? 97.817  107.833 80.321  1.00 150.73 ? 136 GLU B CA  1 
ATOM   4325  C  C   . GLU B 2 136 ? 99.232  108.419 80.224  1.00 158.37 ? 136 GLU B C   1 
ATOM   4326  O  O   . GLU B 2 136 ? 100.165 107.823 80.728  1.00 191.27 ? 136 GLU B O   1 
ATOM   4327  C  CB  . GLU B 2 136 ? 97.441  107.189 78.998  1.00 181.96 ? 136 GLU B CB  1 
ATOM   4328  C  CG  . GLU B 2 136 ? 96.135  106.434 79.047  1.00 192.40 ? 136 GLU B CG  1 
ATOM   4329  C  CD  . GLU B 2 136 ? 96.238  104.968 79.435  1.00 295.58 ? 136 GLU B CD  1 
ATOM   4330  O  OE1 . GLU B 2 136 ? 97.356  104.449 79.586  1.00 287.93 ? 136 GLU B OE1 1 
ATOM   4331  O  OE2 . GLU B 2 136 ? 95.162  104.328 79.578  1.00 367.64 ? 136 GLU B OE2 1 
ATOM   4332  N  N   . LEU B 2 137 ? 99.390  109.576 79.565  1.00 174.12 ? 137 LEU B N   1 
ATOM   4333  C  CA  . LEU B 2 137 ? 100.666 110.235 79.310  1.00 170.68 ? 137 LEU B CA  1 
ATOM   4334  C  C   . LEU B 2 137 ? 101.252 110.838 80.573  1.00 155.64 ? 137 LEU B C   1 
ATOM   4335  O  O   . LEU B 2 137 ? 102.440 110.662 80.849  1.00 137.40 ? 137 LEU B O   1 
ATOM   4336  C  CB  . LEU B 2 137 ? 100.416 111.315 78.262  1.00 169.79 ? 137 LEU B CB  1 
ATOM   4337  C  CG  . LEU B 2 137 ? 101.620 112.169 77.893  1.00 215.85 ? 137 LEU B CG  1 
ATOM   4338  C  CD1 . LEU B 2 137 ? 101.535 112.519 76.404  1.00 285.11 ? 137 LEU B CD1 1 
ATOM   4339  C  CD2 . LEU B 2 137 ? 101.690 113.431 78.764  1.00 247.98 ? 137 LEU B CD2 1 
ATOM   4340  N  N   . LEU B 2 138 ? 100.395 111.559 81.292  1.00 165.21 ? 138 LEU B N   1 
ATOM   4341  C  CA  . LEU B 2 138 ? 100.820 112.319 82.442  1.00 203.30 ? 138 LEU B CA  1 
ATOM   4342  C  C   . LEU B 2 138 ? 101.036 111.412 83.657  1.00 206.71 ? 138 LEU B C   1 
ATOM   4343  O  O   . LEU B 2 138 ? 101.986 111.623 84.414  1.00 171.68 ? 138 LEU B O   1 
ATOM   4344  C  CB  . LEU B 2 138 ? 99.761  113.387 82.714  1.00 196.13 ? 138 LEU B CB  1 
ATOM   4345  C  CG  . LEU B 2 138 ? 100.131 114.353 83.837  1.00 317.69 ? 138 LEU B CG  1 
ATOM   4346  C  CD1 . LEU B 2 138 ? 101.310 115.238 83.446  1.00 365.62 ? 138 LEU B CD1 1 
ATOM   4347  C  CD2 . LEU B 2 138 ? 98.935  115.204 84.225  1.00 396.28 ? 138 LEU B CD2 1 
ATOM   4348  N  N   . ILE B 2 139 ? 100.158 110.419 83.868  1.00 191.67 ? 139 ILE B N   1 
ATOM   4349  C  CA  . ILE B 2 139 ? 100.120 109.717 85.150  1.00 182.48 ? 139 ILE B CA  1 
ATOM   4350  C  C   . ILE B 2 139 ? 100.219 108.208 84.988  1.00 150.35 ? 139 ILE B C   1 
ATOM   4351  O  O   . ILE B 2 139 ? 101.189 107.639 85.477  1.00 114.51 ? 139 ILE B O   1 
ATOM   4352  C  CB  . ILE B 2 139 ? 98.890  110.126 85.986  1.00 179.49 ? 139 ILE B CB  1 
ATOM   4353  C  CG1 . ILE B 2 139 ? 98.856  111.643 86.107  1.00 266.23 ? 139 ILE B CG1 1 
ATOM   4354  C  CG2 . ILE B 2 139 ? 98.934  109.463 87.344  1.00 161.06 ? 139 ILE B CG2 1 
ATOM   4355  C  CD1 . ILE B 2 139 ? 97.912  112.191 87.135  1.00 334.10 ? 139 ILE B CD1 1 
ATOM   4356  N  N   . ILE B 2 140 ? 99.237  107.584 84.344  1.00 139.95 ? 140 ILE B N   1 
ATOM   4357  C  CA  . ILE B 2 140 ? 99.047  106.147 84.504  1.00 120.33 ? 140 ILE B CA  1 
ATOM   4358  C  C   . ILE B 2 140 ? 100.245 105.360 83.972  1.00 131.11 ? 140 ILE B C   1 
ATOM   4359  O  O   . ILE B 2 140 ? 100.789 104.551 84.709  1.00 149.61 ? 140 ILE B O   1 
ATOM   4360  C  CB  . ILE B 2 140 ? 97.751  105.683 83.830  1.00 118.71 ? 140 ILE B CB  1 
ATOM   4361  C  CG1 . ILE B 2 140 ? 96.575  106.488 84.374  1.00 134.46 ? 140 ILE B CG1 1 
ATOM   4362  C  CG2 . ILE B 2 140 ? 97.537  104.175 83.947  1.00 137.57 ? 140 ILE B CG2 1 
ATOM   4363  C  CD1 . ILE B 2 140 ? 96.446  106.512 85.870  1.00 133.12 ? 140 ILE B CD1 1 
ATOM   4364  N  N   . ARG B 2 141 ? 100.658 105.575 82.720  1.00 86.29  ? 141 ARG B N   1 
ATOM   4365  C  CA  . ARG B 2 141 ? 101.758 104.807 82.187  1.00 118.27 ? 141 ARG B CA  1 
ATOM   4366  C  C   . ARG B 2 141 ? 103.105 105.126 82.868  1.00 125.58 ? 141 ARG B C   1 
ATOM   4367  O  O   . ARG B 2 141 ? 103.819 104.199 83.235  1.00 140.37 ? 141 ARG B O   1 
ATOM   4368  C  CB  . ARG B 2 141 ? 101.775 104.944 80.661  1.00 146.25 ? 141 ARG B CB  1 
ATOM   4369  C  CG  . ARG B 2 141 ? 100.476 104.467 80.034  1.00 134.87 ? 141 ARG B CG  1 
ATOM   4370  C  CD  . ARG B 2 141 ? 100.131 103.018 80.316  1.00 141.41 ? 141 ARG B CD  1 
ATOM   4371  N  NE  . ARG B 2 141 ? 100.482 102.153 79.190  1.00 172.48 ? 141 ARG B NE  1 
ATOM   4372  C  CZ  . ARG B 2 141 ? 99.607  101.726 78.280  1.00 210.55 ? 141 ARG B CZ  1 
ATOM   4373  N  NH1 . ARG B 2 141 ? 99.959  100.807 77.391  1.00 156.53 ? 141 ARG B NH1 1 
ATOM   4374  N  NH2 . ARG B 2 141 ? 98.372  102.207 78.279  1.00 250.00 ? 141 ARG B NH2 1 
ATOM   4375  N  N   . PRO B 2 142 ? 103.548 106.374 83.062  1.00 105.81 ? 142 PRO B N   1 
ATOM   4376  C  CA  . PRO B 2 142 ? 104.810 106.581 83.739  1.00 117.46 ? 142 PRO B CA  1 
ATOM   4377  C  C   . PRO B 2 142 ? 104.793 106.167 85.213  1.00 151.90 ? 142 PRO B C   1 
ATOM   4378  O  O   . PRO B 2 142 ? 105.785 105.635 85.695  1.00 167.58 ? 142 PRO B O   1 
ATOM   4379  C  CB  . PRO B 2 142 ? 105.016 108.083 83.518  1.00 149.54 ? 142 PRO B CB  1 
ATOM   4380  C  CG  . PRO B 2 142 ? 103.634 108.676 83.406  1.00 122.12 ? 142 PRO B CG  1 
ATOM   4381  C  CD  . PRO B 2 142 ? 102.926 107.623 82.616  1.00 131.71 ? 142 PRO B CD  1 
ATOM   4382  N  N   . SER B 2 143 ? 103.702 106.371 85.964  1.00 138.98 ? 143 SER B N   1 
ATOM   4383  C  CA  . SER B 2 143 ? 103.656 105.826 87.314  1.00 142.08 ? 143 SER B CA  1 
ATOM   4384  C  C   . SER B 2 143 ? 103.704 104.292 87.308  1.00 123.36 ? 143 SER B C   1 
ATOM   4385  O  O   . SER B 2 143 ? 104.468 103.673 88.020  1.00 101.56 ? 143 SER B O   1 
ATOM   4386  C  CB  . SER B 2 143 ? 102.429 106.234 88.059  1.00 145.83 ? 143 SER B CB  1 
ATOM   4387  O  OG  . SER B 2 143 ? 102.180 107.605 87.979  1.00 134.70 ? 143 SER B OG  1 
ATOM   4388  N  N   . SER B 2 144 ? 102.849 103.637 86.544  1.00 109.96 ? 144 SER B N   1 
ATOM   4389  C  CA  . SER B 2 144 ? 102.910 102.200 86.407  1.00 138.77 ? 144 SER B CA  1 
ATOM   4390  C  C   . SER B 2 144 ? 104.336 101.726 86.089  1.00 106.74 ? 144 SER B C   1 
ATOM   4391  O  O   . SER B 2 144 ? 104.845 100.818 86.730  1.00 82.24  ? 144 SER B O   1 
ATOM   4392  C  CB  . SER B 2 144 ? 101.884 101.738 85.343  1.00 167.71 ? 144 SER B CB  1 
ATOM   4393  O  OG  . SER B 2 144 ? 102.027 100.376 84.924  1.00 141.88 ? 144 SER B OG  1 
ATOM   4394  N  N   . GLN B 2 145 ? 104.984 102.278 85.059  1.00 102.98 ? 145 GLN B N   1 
ATOM   4395  C  CA  . GLN B 2 145 ? 106.318 101.844 84.650  1.00 125.36 ? 145 GLN B CA  1 
ATOM   4396  C  C   . GLN B 2 145 ? 107.279 101.999 85.823  1.00 100.09 ? 145 GLN B C   1 
ATOM   4397  O  O   . GLN B 2 145 ? 108.106 101.139 86.078  1.00 77.93  ? 145 GLN B O   1 
ATOM   4398  C  CB  . GLN B 2 145 ? 106.792 102.620 83.413  1.00 114.59 ? 145 GLN B CB  1 
ATOM   4399  C  CG  . GLN B 2 145 ? 106.073 102.212 82.139  1.00 131.09 ? 145 GLN B CG  1 
ATOM   4400  C  CD  . GLN B 2 145 ? 105.868 103.270 81.076  1.00 207.51 ? 145 GLN B CD  1 
ATOM   4401  O  OE1 . GLN B 2 145 ? 105.066 103.127 80.153  1.00 222.98 ? 145 GLN B OE1 1 
ATOM   4402  N  NE2 . GLN B 2 145 ? 106.574 104.375 81.181  1.00 278.94 ? 145 GLN B NE2 1 
ATOM   4403  N  N   . TYR B 2 146 ? 107.196 103.114 86.547  1.00 109.83 ? 146 TYR B N   1 
ATOM   4404  C  CA  . TYR B 2 146 ? 108.126 103.360 87.634  1.00 122.52 ? 146 TYR B CA  1 
ATOM   4405  C  C   . TYR B 2 146 ? 107.905 102.387 88.785  1.00 95.06  ? 146 TYR B C   1 
ATOM   4406  O  O   . TYR B 2 146 ? 108.863 101.827 89.280  1.00 74.27  ? 146 TYR B O   1 
ATOM   4407  C  CB  . TYR B 2 146 ? 108.011 104.812 88.118  1.00 129.32 ? 146 TYR B CB  1 
ATOM   4408  C  CG  . TYR B 2 146 ? 109.049 105.014 89.210  1.00 129.37 ? 146 TYR B CG  1 
ATOM   4409  C  CD1 . TYR B 2 146 ? 110.412 104.968 88.897  1.00 159.09 ? 146 TYR B CD1 1 
ATOM   4410  C  CD2 . TYR B 2 146 ? 108.656 105.205 90.526  1.00 119.84 ? 146 TYR B CD2 1 
ATOM   4411  C  CE1 . TYR B 2 146 ? 111.358 105.128 89.879  1.00 158.61 ? 146 TYR B CE1 1 
ATOM   4412  C  CE2 . TYR B 2 146 ? 109.599 105.368 91.517  1.00 157.57 ? 146 TYR B CE2 1 
ATOM   4413  C  CZ  . TYR B 2 146 ? 110.943 105.326 91.181  1.00 175.76 ? 146 TYR B CZ  1 
ATOM   4414  O  OH  . TYR B 2 146 ? 111.905 105.496 92.103  1.00 161.76 ? 146 TYR B OH  1 
ATOM   4415  N  N   . ILE B 2 147 ? 106.644 102.236 89.204  1.00 107.71 ? 147 ILE B N   1 
ATOM   4416  C  CA  . ILE B 2 147 ? 106.266 101.386 90.298  1.00 92.24  ? 147 ILE B CA  1 
ATOM   4417  C  C   . ILE B 2 147 ? 106.785 99.990  90.026  1.00 95.97  ? 147 ILE B C   1 
ATOM   4418  O  O   . ILE B 2 147 ? 107.375 99.380  90.916  1.00 129.20 ? 147 ILE B O   1 
ATOM   4419  C  CB  . ILE B 2 147 ? 104.739 101.380 90.439  1.00 98.25  ? 147 ILE B CB  1 
ATOM   4420  C  CG1 . ILE B 2 147 ? 104.298 102.713 91.010  1.00 110.27 ? 147 ILE B CG1 1 
ATOM   4421  C  CG2 . ILE B 2 147 ? 104.228 100.164 91.252  1.00 146.53 ? 147 ILE B CG2 1 
ATOM   4422  C  CD1 . ILE B 2 147 ? 102.816 102.945 90.794  1.00 186.98 ? 147 ILE B CD1 1 
ATOM   4423  N  N   . VAL B 2 148 ? 106.543 99.451  88.836  1.00 83.05  ? 148 VAL B N   1 
ATOM   4424  C  CA  . VAL B 2 148 ? 106.914 98.074  88.651  1.00 97.73  ? 148 VAL B CA  1 
ATOM   4425  C  C   . VAL B 2 148 ? 108.433 97.987  88.514  1.00 89.55  ? 148 VAL B C   1 
ATOM   4426  O  O   . VAL B 2 148 ? 109.000 96.941  88.818  1.00 103.96 ? 148 VAL B O   1 
ATOM   4427  C  CB  . VAL B 2 148 ? 106.121 97.423  87.504  1.00 125.18 ? 148 VAL B CB  1 
ATOM   4428  C  CG1 . VAL B 2 148 ? 106.570 97.873  86.118  1.00 115.64 ? 148 VAL B CG1 1 
ATOM   4429  C  CG2 . VAL B 2 148 ? 106.130 95.890  87.598  1.00 159.11 ? 148 VAL B CG2 1 
ATOM   4430  N  N   . ALA B 2 149 ? 109.114 99.047  88.076  1.00 78.33  ? 149 ALA B N   1 
ATOM   4431  C  CA  . ALA B 2 149 ? 110.567 99.021  88.055  1.00 83.61  ? 149 ALA B CA  1 
ATOM   4432  C  C   . ALA B 2 149 ? 111.105 99.013  89.457  1.00 83.78  ? 149 ALA B C   1 
ATOM   4433  O  O   . ALA B 2 149 ? 112.102 98.366  89.701  1.00 83.91  ? 149 ALA B O   1 
ATOM   4434  C  CB  . ALA B 2 149 ? 111.092 100.212 87.309  1.00 126.85 ? 149 ALA B CB  1 
ATOM   4435  N  N   . LEU B 2 150 ? 110.478 99.759  90.370  1.00 120.30 ? 150 LEU B N   1 
ATOM   4436  C  CA  . LEU B 2 150 ? 110.907 99.806  91.768  1.00 120.73 ? 150 LEU B CA  1 
ATOM   4437  C  C   . LEU B 2 150 ? 110.648 98.474  92.454  1.00 115.48 ? 150 LEU B C   1 
ATOM   4438  O  O   . LEU B 2 150 ? 111.405 98.129  93.345  1.00 97.69  ? 150 LEU B O   1 
ATOM   4439  C  CB  . LEU B 2 150 ? 110.151 100.934 92.462  1.00 123.52 ? 150 LEU B CB  1 
ATOM   4440  C  CG  . LEU B 2 150 ? 110.683 101.328 93.820  1.00 155.37 ? 150 LEU B CG  1 
ATOM   4441  C  CD1 . LEU B 2 150 ? 112.111 101.857 93.699  1.00 136.24 ? 150 LEU B CD1 1 
ATOM   4442  C  CD2 . LEU B 2 150 ? 109.732 102.359 94.437  1.00 241.74 ? 150 LEU B CD2 1 
ATOM   4443  N  N   . VAL B 2 151 ? 109.606 97.733  92.022  1.00 90.73  ? 151 VAL B N   1 
ATOM   4444  C  CA  . VAL B 2 151 ? 109.405 96.376  92.493  1.00 83.94  ? 151 VAL B CA  1 
ATOM   4445  C  C   . VAL B 2 151 ? 110.473 95.456  91.931  1.00 69.34  ? 151 VAL B C   1 
ATOM   4446  O  O   . VAL B 2 151 ? 110.984 94.610  92.677  1.00 87.09  ? 151 VAL B O   1 
ATOM   4447  C  CB  . VAL B 2 151 ? 107.992 95.839  92.244  1.00 101.10 ? 151 VAL B CB  1 
ATOM   4448  C  CG1 . VAL B 2 151 ? 107.869 94.362  92.645  1.00 79.25  ? 151 VAL B CG1 1 
ATOM   4449  C  CG2 . VAL B 2 151 ? 106.933 96.668  92.990  1.00 143.50 ? 151 VAL B CG2 1 
ATOM   4450  N  N   . PHE B 2 152 ? 110.845 95.619  90.676  1.00 76.90  ? 152 PHE B N   1 
ATOM   4451  C  CA  . PHE B 2 152 ? 112.023 94.927  90.172  1.00 121.29 ? 152 PHE B CA  1 
ATOM   4452  C  C   . PHE B 2 152 ? 113.252 95.193  91.043  1.00 106.58 ? 152 PHE B C   1 
ATOM   4453  O  O   . PHE B 2 152 ? 113.957 94.255  91.430  1.00 117.45 ? 152 PHE B O   1 
ATOM   4454  C  CB  . PHE B 2 152 ? 112.320 95.299  88.711  1.00 124.25 ? 152 PHE B CB  1 
ATOM   4455  C  CG  . PHE B 2 152 ? 113.742 95.063  88.279  1.00 112.27 ? 152 PHE B CG  1 
ATOM   4456  C  CD1 . PHE B 2 152 ? 114.168 93.810  87.847  1.00 118.21 ? 152 PHE B CD1 1 
ATOM   4457  C  CD2 . PHE B 2 152 ? 114.637 96.107  88.320  1.00 116.56 ? 152 PHE B CD2 1 
ATOM   4458  C  CE1 . PHE B 2 152 ? 115.474 93.614  87.456  1.00 155.77 ? 152 PHE B CE1 1 
ATOM   4459  C  CE2 . PHE B 2 152 ? 115.947 95.911  87.931  1.00 156.25 ? 152 PHE B CE2 1 
ATOM   4460  C  CZ  . PHE B 2 152 ? 116.357 94.671  87.498  1.00 174.88 ? 152 PHE B CZ  1 
ATOM   4461  N  N   . ALA B 2 153 ? 113.528 96.465  91.327  1.00 92.44  ? 153 ALA B N   1 
ATOM   4462  C  CA  . ALA B 2 153 ? 114.718 96.836  92.058  1.00 122.97 ? 153 ALA B CA  1 
ATOM   4463  C  C   . ALA B 2 153 ? 114.684 96.205  93.443  1.00 121.36 ? 153 ALA B C   1 
ATOM   4464  O  O   . ALA B 2 153 ? 115.664 95.594  93.862  1.00 100.15 ? 153 ALA B O   1 
ATOM   4465  C  CB  . ALA B 2 153 ? 114.865 98.339  92.095  1.00 116.52 ? 153 ALA B CB  1 
ATOM   4466  N  N   . THR B 2 154 ? 113.586 96.352  94.183  1.00 109.43 ? 154 THR B N   1 
ATOM   4467  C  CA  . THR B 2 154 ? 113.598 95.907  95.564  1.00 127.33 ? 154 THR B CA  1 
ATOM   4468  C  C   . THR B 2 154 ? 113.715 94.387  95.614  1.00 94.54  ? 154 THR B C   1 
ATOM   4469  O  O   . THR B 2 154 ? 114.540 93.866  96.349  1.00 99.77  ? 154 THR B O   1 
ATOM   4470  C  CB  . THR B 2 154 ? 112.467 96.581  96.360  1.00 124.90 ? 154 THR B CB  1 
ATOM   4471  O  OG1 . THR B 2 154 ? 112.699 96.317  97.749  1.00 174.88 ? 154 THR B OG1 1 
ATOM   4472  C  CG2 . THR B 2 154 ? 111.119 96.070  95.969  1.00 151.34 ? 154 THR B CG2 1 
ATOM   4473  N  N   . TYR B 2 155 ? 112.911 93.659  94.874  1.00 103.31 ? 155 TYR B N   1 
ATOM   4474  C  CA  . TYR B 2 155 ? 112.942 92.209  95.018  1.00 114.91 ? 155 TYR B CA  1 
ATOM   4475  C  C   . TYR B 2 155 ? 114.231 91.609  94.461  1.00 106.60 ? 155 TYR B C   1 
ATOM   4476  O  O   . TYR B 2 155 ? 114.669 90.593  94.973  1.00 132.90 ? 155 TYR B O   1 
ATOM   4477  C  CB  . TYR B 2 155 ? 111.738 91.504  94.392  1.00 95.45  ? 155 TYR B CB  1 
ATOM   4478  C  CG  . TYR B 2 155 ? 110.573 91.590  95.326  1.00 94.76  ? 155 TYR B CG  1 
ATOM   4479  C  CD1 . TYR B 2 155 ? 109.792 92.740  95.396  1.00 129.85 ? 155 TYR B CD1 1 
ATOM   4480  C  CD2 . TYR B 2 155 ? 110.260 90.534  96.118  1.00 115.05 ? 155 TYR B CD2 1 
ATOM   4481  C  CE1 . TYR B 2 155 ? 108.694 92.851  96.236  1.00 129.95 ? 155 TYR B CE1 1 
ATOM   4482  C  CE2 . TYR B 2 155 ? 109.165 90.638  96.967  1.00 214.55 ? 155 TYR B CE2 1 
ATOM   4483  C  CZ  . TYR B 2 155 ? 108.383 91.787  97.034  1.00 178.05 ? 155 TYR B CZ  1 
ATOM   4484  O  OH  . TYR B 2 155 ? 107.306 91.902  97.862  1.00 252.01 ? 155 TYR B OH  1 
ATOM   4485  N  N   . LEU B 2 156 ? 114.839 92.176  93.423  1.00 138.11 ? 156 LEU B N   1 
ATOM   4486  C  CA  . LEU B 2 156 ? 116.090 91.627  92.915  1.00 157.65 ? 156 LEU B CA  1 
ATOM   4487  C  C   . LEU B 2 156 ? 117.218 91.805  93.930  1.00 135.70 ? 156 LEU B C   1 
ATOM   4488  O  O   . LEU B 2 156 ? 118.097 90.938  93.997  1.00 168.51 ? 156 LEU B O   1 
ATOM   4489  C  CB  . LEU B 2 156 ? 116.407 92.328  91.598  1.00 172.95 ? 156 LEU B CB  1 
ATOM   4490  C  CG  . LEU B 2 156 ? 117.725 91.928  90.977  1.00 189.76 ? 156 LEU B CG  1 
ATOM   4491  C  CD1 . LEU B 2 156 ? 117.640 90.476  90.506  1.00 219.12 ? 156 LEU B CD1 1 
ATOM   4492  C  CD2 . LEU B 2 156 ? 118.058 92.908  89.885  1.00 215.49 ? 156 LEU B CD2 1 
ATOM   4493  N  N   . LEU B 2 157 ? 117.175 92.901  94.709  1.00 104.62 ? 157 LEU B N   1 
ATOM   4494  C  CA  . LEU B 2 157 ? 118.163 93.160  95.739  1.00 123.04 ? 157 LEU B CA  1 
ATOM   4495  C  C   . LEU B 2 157 ? 117.883 92.377  97.020  1.00 105.38 ? 157 LEU B C   1 
ATOM   4496  O  O   . LEU B 2 157 ? 118.840 92.103  97.741  1.00 100.60 ? 157 LEU B O   1 
ATOM   4497  C  CB  . LEU B 2 157 ? 118.141 94.661  96.004  1.00 115.93 ? 157 LEU B CB  1 
ATOM   4498  C  CG  . LEU B 2 157 ? 118.713 95.519  94.887  1.00 130.49 ? 157 LEU B CG  1 
ATOM   4499  C  CD1 . LEU B 2 157 ? 118.363 97.039  95.064  1.00 93.28  ? 157 LEU B CD1 1 
ATOM   4500  C  CD2 . LEU B 2 157 ? 120.226 95.269  94.871  1.00 132.78 ? 157 LEU B CD2 1 
ATOM   4501  N  N   . LYS B 2 158 ? 116.612 92.034  97.283  1.00 110.54 ? 158 LYS B N   1 
ATOM   4502  C  CA  . LYS B 2 158 ? 116.114 91.543  98.566  1.00 129.69 ? 158 LYS B CA  1 
ATOM   4503  C  C   . LYS B 2 158 ? 116.996 90.473  99.190  1.00 108.14 ? 158 LYS B C   1 
ATOM   4504  O  O   . LYS B 2 158 ? 117.192 90.548  100.386 1.00 170.26 ? 158 LYS B O   1 
ATOM   4505  C  CB  . LYS B 2 158 ? 114.664 91.018  98.456  1.00 171.35 ? 158 LYS B CB  1 
ATOM   4506  C  CG  . LYS B 2 158 ? 113.933 90.724  99.763  1.00 171.54 ? 158 LYS B CG  1 
ATOM   4507  C  CD  . LYS B 2 158 ? 113.773 91.976  100.604 1.00 198.17 ? 158 LYS B CD  1 
ATOM   4508  C  CE  . LYS B 2 158 ? 112.802 91.854  101.757 1.00 232.48 ? 158 LYS B CE  1 
ATOM   4509  N  NZ  . LYS B 2 158 ? 112.749 93.090  102.585 1.00 262.44 ? 158 LYS B NZ  1 
ATOM   4510  N  N   . PRO B 2 159 ? 117.514 89.431  98.523  1.00 100.91 ? 159 PRO B N   1 
ATOM   4511  C  CA  . PRO B 2 159 ? 118.332 88.452  99.228  1.00 131.21 ? 159 PRO B CA  1 
ATOM   4512  C  C   . PRO B 2 159 ? 119.711 88.945  99.709  1.00 130.64 ? 159 PRO B C   1 
ATOM   4513  O  O   . PRO B 2 159 ? 120.373 88.206  100.445 1.00 189.81 ? 159 PRO B O   1 
ATOM   4514  C  CB  . PRO B 2 159 ? 118.407 87.310  98.212  1.00 165.79 ? 159 PRO B CB  1 
ATOM   4515  C  CG  . PRO B 2 159 ? 118.278 87.986  96.894  1.00 172.99 ? 159 PRO B CG  1 
ATOM   4516  C  CD  . PRO B 2 159 ? 117.292 89.090  97.130  1.00 135.70 ? 159 PRO B CD  1 
ATOM   4517  N  N   . LEU B 2 160 ? 120.150 90.159  99.351  1.00 100.39 ? 160 LEU B N   1 
ATOM   4518  C  CA  . LEU B 2 160 ? 121.267 90.802  100.069 1.00 141.18 ? 160 LEU B CA  1 
ATOM   4519  C  C   . LEU B 2 160 ? 120.859 91.426  101.420 1.00 154.10 ? 160 LEU B C   1 
ATOM   4520  O  O   . LEU B 2 160 ? 121.711 91.668  102.277 1.00 133.36 ? 160 LEU B O   1 
ATOM   4521  C  CB  . LEU B 2 160 ? 121.856 91.939  99.242  1.00 135.19 ? 160 LEU B CB  1 
ATOM   4522  C  CG  . LEU B 2 160 ? 122.395 91.571  97.882  1.00 204.97 ? 160 LEU B CG  1 
ATOM   4523  C  CD1 . LEU B 2 160 ? 122.729 92.860  97.152  1.00 238.11 ? 160 LEU B CD1 1 
ATOM   4524  C  CD2 . LEU B 2 160 ? 123.606 90.660  98.019  1.00 263.35 ? 160 LEU B CD2 1 
ATOM   4525  N  N   . PHE B 2 161 ? 119.554 91.678  101.595 1.00 131.10 ? 161 PHE B N   1 
ATOM   4526  C  CA  . PHE B 2 161 ? 118.968 92.372  102.719 1.00 118.20 ? 161 PHE B CA  1 
ATOM   4527  C  C   . PHE B 2 161 ? 117.722 91.617  103.202 1.00 135.83 ? 161 PHE B C   1 
ATOM   4528  O  O   . PHE B 2 161 ? 116.617 92.160  103.134 1.00 135.95 ? 161 PHE B O   1 
ATOM   4529  C  CB  . PHE B 2 161 ? 118.654 93.829  102.304 1.00 105.72 ? 161 PHE B CB  1 
ATOM   4530  C  CG  . PHE B 2 161 ? 119.858 94.611  101.830 1.00 87.12  ? 161 PHE B CG  1 
ATOM   4531  C  CD1 . PHE B 2 161 ? 120.809 95.071  102.706 1.00 147.26 ? 161 PHE B CD1 1 
ATOM   4532  C  CD2 . PHE B 2 161 ? 120.054 94.875  100.528 1.00 108.40 ? 161 PHE B CD2 1 
ATOM   4533  C  CE1 . PHE B 2 161 ? 121.927 95.762  102.302 1.00 160.91 ? 161 PHE B CE1 1 
ATOM   4534  C  CE2 . PHE B 2 161 ? 121.163 95.564  100.113 1.00 155.59 ? 161 PHE B CE2 1 
ATOM   4535  C  CZ  . PHE B 2 161 ? 122.098 96.006  100.998 1.00 147.21 ? 161 PHE B CZ  1 
ATOM   4536  N  N   . PRO B 2 162 ? 117.853 90.373  103.728 1.00 123.73 ? 162 PRO B N   1 
ATOM   4537  C  CA  . PRO B 2 162 ? 116.679 89.515  103.933 1.00 151.67 ? 162 PRO B CA  1 
ATOM   4538  C  C   . PRO B 2 162 ? 115.663 89.996  104.973 1.00 170.29 ? 162 PRO B C   1 
ATOM   4539  O  O   . PRO B 2 162 ? 114.471 89.734  104.813 1.00 239.37 ? 162 PRO B O   1 
ATOM   4540  C  CB  . PRO B 2 162 ? 117.284 88.178  104.384 1.00 216.88 ? 162 PRO B CB  1 
ATOM   4541  C  CG  . PRO B 2 162 ? 118.764 88.280  103.998 1.00 231.77 ? 162 PRO B CG  1 
ATOM   4542  C  CD  . PRO B 2 162 ? 119.113 89.748  104.158 1.00 142.71 ? 162 PRO B CD  1 
ATOM   4543  N  N   . THR B 2 163 ? 116.131 90.688  106.024 1.00 126.82 ? 163 THR B N   1 
ATOM   4544  C  CA  . THR B 2 163 ? 115.323 90.896  107.216 1.00 147.77 ? 163 THR B CA  1 
ATOM   4545  C  C   . THR B 2 163 ? 114.874 92.354  107.344 1.00 147.40 ? 163 THR B C   1 
ATOM   4546  O  O   . THR B 2 163 ? 114.207 92.700  108.320 1.00 192.17 ? 163 THR B O   1 
ATOM   4547  C  CB  . THR B 2 163 ? 116.075 90.443  108.482 1.00 226.17 ? 163 THR B CB  1 
ATOM   4548  O  OG1 . THR B 2 163 ? 117.268 91.209  108.607 1.00 230.86 ? 163 THR B OG1 1 
ATOM   4549  C  CG2 . THR B 2 163 ? 116.420 88.970  108.469 1.00 244.19 ? 163 THR B CG2 1 
ATOM   4550  N  N   . CYS B 2 164 ? 115.210 93.200  106.364 1.00 130.49 ? 164 CYS B N   1 
ATOM   4551  C  CA  . CYS B 2 164 ? 115.188 94.647  106.548 1.00 139.04 ? 164 CYS B CA  1 
ATOM   4552  C  C   . CYS B 2 164 ? 114.950 95.379  105.234 1.00 132.42 ? 164 CYS B C   1 
ATOM   4553  O  O   . CYS B 2 164 ? 114.877 94.722  104.197 1.00 214.99 ? 164 CYS B O   1 
ATOM   4554  C  CB  . CYS B 2 164 ? 116.505 95.063  107.174 1.00 143.00 ? 164 CYS B CB  1 
ATOM   4555  S  SG  . CYS B 2 164 ? 117.944 94.907  106.103 1.00 152.79 ? 164 CYS B SG  1 
ATOM   4556  N  N   . PRO B 2 165 ? 114.784 96.718  105.214 1.00 116.35 ? 165 PRO B N   1 
ATOM   4557  C  CA  . PRO B 2 165 ? 114.655 97.446  103.957 1.00 168.57 ? 165 PRO B CA  1 
ATOM   4558  C  C   . PRO B 2 165 ? 115.937 97.360  103.124 1.00 214.91 ? 165 PRO B C   1 
ATOM   4559  O  O   . PRO B 2 165 ? 117.047 97.361  103.668 1.00 150.68 ? 165 PRO B O   1 
ATOM   4560  C  CB  . PRO B 2 165 ? 114.378 98.900  104.352 1.00 200.63 ? 165 PRO B CB  1 
ATOM   4561  C  CG  . PRO B 2 165 ? 113.859 98.772  105.756 1.00 240.57 ? 165 PRO B CG  1 
ATOM   4562  C  CD  . PRO B 2 165 ? 114.674 97.634  106.346 1.00 200.53 ? 165 PRO B CD  1 
ATOM   4563  N  N   . VAL B 2 166 ? 115.733 97.276  101.798 1.00 214.36 ? 166 VAL B N   1 
ATOM   4564  C  CA  . VAL B 2 166 ? 116.789 97.468  100.826 1.00 131.71 ? 166 VAL B CA  1 
ATOM   4565  C  C   . VAL B 2 166 ? 117.017 98.970  100.753 1.00 140.77 ? 166 VAL B C   1 
ATOM   4566  O  O   . VAL B 2 166 ? 116.005 99.699  100.623 1.00 114.68 ? 166 VAL B O   1 
ATOM   4567  C  CB  . VAL B 2 166 ? 116.351 96.918  99.466  1.00 145.80 ? 166 VAL B CB  1 
ATOM   4568  C  CG1 . VAL B 2 166 ? 117.367 97.238  98.402  1.00 172.57 ? 166 VAL B CG1 1 
ATOM   4569  C  CG2 . VAL B 2 166 ? 116.062 95.428  99.484  1.00 168.07 ? 166 VAL B CG2 1 
ATOM   4570  N  N   . PRO B 2 167 ? 118.292 99.463  100.819 1.00 144.17 ? 167 PRO B N   1 
ATOM   4571  C  CA  . PRO B 2 167 ? 118.614 100.914 100.876 1.00 145.67 ? 167 PRO B CA  1 
ATOM   4572  C  C   . PRO B 2 167 ? 117.949 101.772 99.810  1.00 111.98 ? 167 PRO B C   1 
ATOM   4573  O  O   . PRO B 2 167 ? 118.090 101.459 98.618  1.00 228.72 ? 167 PRO B O   1 
ATOM   4574  C  CB  . PRO B 2 167 ? 120.131 100.925 100.636 1.00 166.72 ? 167 PRO B CB  1 
ATOM   4575  C  CG  . PRO B 2 167 ? 120.635 99.558  101.124 1.00 134.51 ? 167 PRO B CG  1 
ATOM   4576  C  CD  . PRO B 2 167 ? 119.496 98.618  100.844 1.00 89.66  ? 167 PRO B CD  1 
ATOM   4577  N  N   . GLU B 2 168 ? 117.183 102.801 100.191 1.00 148.75 ? 168 GLU B N   1 
ATOM   4578  C  CA  . GLU B 2 168 ? 116.263 103.454 99.238  1.00 202.00 ? 168 GLU B CA  1 
ATOM   4579  C  C   . GLU B 2 168 ? 117.026 104.183 98.121  1.00 189.95 ? 168 GLU B C   1 
ATOM   4580  O  O   . GLU B 2 168 ? 116.630 104.157 96.954  1.00 198.52 ? 168 GLU B O   1 
ATOM   4581  C  CB  . GLU B 2 168 ? 115.282 104.420 99.914  1.00 222.75 ? 168 GLU B CB  1 
ATOM   4582  C  CG  . GLU B 2 168 ? 114.295 103.725 100.844 1.00 334.22 ? 168 GLU B CG  1 
ATOM   4583  C  CD  . GLU B 2 168 ? 114.690 103.607 102.315 1.00 487.15 ? 168 GLU B CD  1 
ATOM   4584  O  OE1 . GLU B 2 168 ? 115.864 103.278 102.605 1.00 524.79 ? 168 GLU B OE1 1 
ATOM   4585  O  OE2 . GLU B 2 168 ? 113.816 103.841 103.182 1.00 571.51 ? 168 GLU B OE2 1 
ATOM   4586  N  N   . GLU B 2 169 ? 118.142 104.823 98.449  1.00 189.34 ? 169 GLU B N   1 
ATOM   4587  C  CA  . GLU B 2 169 ? 118.951 105.438 97.409  1.00 189.40 ? 169 GLU B CA  1 
ATOM   4588  C  C   . GLU B 2 169 ? 119.534 104.401 96.441  1.00 124.05 ? 169 GLU B C   1 
ATOM   4589  O  O   . GLU B 2 169 ? 119.995 104.823 95.407  1.00 233.23 ? 169 GLU B O   1 
ATOM   4590  C  CB  . GLU B 2 169 ? 120.118 106.243 98.005  1.00 321.25 ? 169 GLU B CB  1 
ATOM   4591  C  CG  . GLU B 2 169 ? 119.722 107.355 98.980  1.00 422.73 ? 169 GLU B CG  1 
ATOM   4592  C  CD  . GLU B 2 169 ? 119.627 106.975 100.451 1.00 509.44 ? 169 GLU B CD  1 
ATOM   4593  O  OE1 . GLU B 2 169 ? 119.622 105.767 100.756 1.00 480.07 ? 169 GLU B OE1 1 
ATOM   4594  O  OE2 . GLU B 2 169 ? 119.559 107.894 101.295 1.00 599.00 ? 169 GLU B OE2 1 
ATOM   4595  N  N   . ALA B 2 170 ? 119.605 103.097 96.766  1.00 152.41 ? 170 ALA B N   1 
ATOM   4596  C  CA  . ALA B 2 170 ? 120.017 102.026 95.843  1.00 149.41 ? 170 ALA B CA  1 
ATOM   4597  C  C   . ALA B 2 170 ? 118.819 101.553 95.048  1.00 110.39 ? 170 ALA B C   1 
ATOM   4598  O  O   . ALA B 2 170 ? 118.921 101.389 93.851  1.00 135.06 ? 170 ALA B O   1 
ATOM   4599  C  CB  . ALA B 2 170 ? 120.668 100.801 96.487  1.00 101.49 ? 170 ALA B CB  1 
ATOM   4600  N  N   . ALA B 2 171 ? 117.692 101.359 95.701  1.00 125.69 ? 171 ALA B N   1 
ATOM   4601  C  CA  . ALA B 2 171 ? 116.495 100.922 95.016  1.00 141.47 ? 171 ALA B CA  1 
ATOM   4602  C  C   . ALA B 2 171 ? 116.118 101.880 93.899  1.00 108.73 ? 171 ALA B C   1 
ATOM   4603  O  O   . ALA B 2 171 ? 115.775 101.398 92.832  1.00 147.29 ? 171 ALA B O   1 
ATOM   4604  C  CB  . ALA B 2 171 ? 115.368 100.799 96.018  1.00 213.65 ? 171 ALA B CB  1 
ATOM   4605  N  N   . LYS B 2 172 ? 116.162 103.207 94.091  1.00 109.80 ? 172 LYS B N   1 
ATOM   4606  C  CA  . LYS B 2 172 ? 115.769 104.116 93.018  1.00 123.11 ? 172 LYS B CA  1 
ATOM   4607  C  C   . LYS B 2 172 ? 116.789 104.107 91.888  1.00 109.30 ? 172 LYS B C   1 
ATOM   4608  O  O   . LYS B 2 172 ? 116.403 104.347 90.759  1.00 120.62 ? 172 LYS B O   1 
ATOM   4609  C  CB  . LYS B 2 172 ? 115.525 105.543 93.509  1.00 149.17 ? 172 LYS B CB  1 
ATOM   4610  C  CG  . LYS B 2 172 ? 114.236 105.677 94.293  1.00 145.69 ? 172 LYS B CG  1 
ATOM   4611  C  CD  . LYS B 2 172 ? 113.789 107.123 94.488  1.00 238.03 ? 172 LYS B CD  1 
ATOM   4612  C  CE  . LYS B 2 172 ? 112.351 107.248 94.961  1.00 305.58 ? 172 LYS B CE  1 
ATOM   4613  N  NZ  . LYS B 2 172 ? 112.083 106.542 96.239  1.00 347.87 ? 172 LYS B NZ  1 
ATOM   4614  N  N   . LEU B 2 173 ? 118.062 103.822 92.125  1.00 130.19 ? 173 LEU B N   1 
ATOM   4615  C  CA  . LEU B 2 173 ? 119.012 103.713 91.016  1.00 124.19 ? 173 LEU B CA  1 
ATOM   4616  C  C   . LEU B 2 173 ? 118.727 102.463 90.237  1.00 95.13  ? 173 LEU B C   1 
ATOM   4617  O  O   . LEU B 2 173 ? 118.692 102.512 89.018  1.00 111.25 ? 173 LEU B O   1 
ATOM   4618  C  CB  . LEU B 2 173 ? 120.474 103.603 91.443  1.00 105.29 ? 173 LEU B CB  1 
ATOM   4619  C  CG  . LEU B 2 173 ? 121.003 104.857 92.144  1.00 164.99 ? 173 LEU B CG  1 
ATOM   4620  C  CD1 . LEU B 2 173 ? 122.514 104.653 92.320  1.00 133.80 ? 173 LEU B CD1 1 
ATOM   4621  C  CD2 . LEU B 2 173 ? 120.560 106.252 91.513  1.00 153.41 ? 173 LEU B CD2 1 
ATOM   4622  N  N   . VAL B 2 174 ? 118.570 101.347 90.938  1.00 76.70  ? 174 VAL B N   1 
ATOM   4623  C  CA  . VAL B 2 174 ? 118.353 100.097 90.240  1.00 98.30  ? 174 VAL B CA  1 
ATOM   4624  C  C   . VAL B 2 174 ? 116.984 100.081 89.522  1.00 93.35  ? 174 VAL B C   1 
ATOM   4625  O  O   . VAL B 2 174 ? 116.827 99.350  88.558  1.00 98.62  ? 174 VAL B O   1 
ATOM   4626  C  CB  . VAL B 2 174 ? 118.666 98.943  91.183  1.00 111.58 ? 174 VAL B CB  1 
ATOM   4627  C  CG1 . VAL B 2 174 ? 118.265 97.562  90.670  1.00 155.41 ? 174 VAL B CG1 1 
ATOM   4628  C  CG2 . VAL B 2 174 ? 120.178 99.025  91.415  1.00 119.02 ? 174 VAL B CG2 1 
ATOM   4629  N  N   . ALA B 2 175 ? 116.028 100.910 89.904  1.00 72.30  ? 175 ALA B N   1 
ATOM   4630  C  CA  . ALA B 2 175 ? 114.853 101.155 89.080  1.00 112.85 ? 175 ALA B CA  1 
ATOM   4631  C  C   . ALA B 2 175 ? 115.206 101.953 87.838  1.00 114.66 ? 175 ALA B C   1 
ATOM   4632  O  O   . ALA B 2 175 ? 114.788 101.602 86.747  1.00 151.06 ? 175 ALA B O   1 
ATOM   4633  C  CB  . ALA B 2 175 ? 113.751 101.861 89.848  1.00 165.06 ? 175 ALA B CB  1 
ATOM   4634  N  N   . CYS B 2 176 ? 115.969 103.025 87.987  1.00 117.44 ? 176 CYS B N   1 
ATOM   4635  C  CA  . CYS B 2 176 ? 116.305 103.862 86.854  1.00 125.54 ? 176 CYS B CA  1 
ATOM   4636  C  C   . CYS B 2 176 ? 117.222 103.162 85.842  1.00 104.51 ? 176 CYS B C   1 
ATOM   4637  O  O   . CYS B 2 176 ? 117.002 103.327 84.654  1.00 121.69 ? 176 CYS B O   1 
ATOM   4638  C  CB  . CYS B 2 176 ? 116.868 105.164 87.391  1.00 137.95 ? 176 CYS B CB  1 
ATOM   4639  S  SG  . CYS B 2 176 ? 115.579 106.063 88.292  1.00 219.72 ? 176 CYS B SG  1 
ATOM   4640  N  N   . LEU B 2 177 ? 118.218 102.406 86.281  1.00 83.06  ? 177 LEU B N   1 
ATOM   4641  C  CA  . LEU B 2 177 ? 119.019 101.576 85.388  1.00 115.01 ? 177 LEU B CA  1 
ATOM   4642  C  C   . LEU B 2 177 ? 118.170 100.634 84.539  1.00 131.31 ? 177 LEU B C   1 
ATOM   4643  O  O   . LEU B 2 177 ? 118.489 100.456 83.358  1.00 226.53 ? 177 LEU B O   1 
ATOM   4644  C  CB  . LEU B 2 177 ? 119.980 100.687 86.180  1.00 139.81 ? 177 LEU B CB  1 
ATOM   4645  C  CG  . LEU B 2 177 ? 121.154 101.407 86.834  1.00 161.17 ? 177 LEU B CG  1 
ATOM   4646  C  CD1 . LEU B 2 177 ? 121.805 100.488 87.839  1.00 195.88 ? 177 LEU B CD1 1 
ATOM   4647  C  CD2 . LEU B 2 177 ? 122.184 101.865 85.820  1.00 154.09 ? 177 LEU B CD2 1 
ATOM   4648  N  N   . CYS B 2 178 ? 117.128 100.034 85.124  1.00 97.61  ? 178 CYS B N   1 
ATOM   4649  C  CA  . CYS B 2 178 ? 116.186 99.203  84.390  1.00 127.31 ? 178 CYS B CA  1 
ATOM   4650  C  C   . CYS B 2 178 ? 115.411 99.962  83.285  1.00 106.90 ? 178 CYS B C   1 
ATOM   4651  O  O   . CYS B 2 178 ? 115.433 99.555  82.105  1.00 128.56 ? 178 CYS B O   1 
ATOM   4652  C  CB  . CYS B 2 178 ? 115.239 98.562  85.390  1.00 148.42 ? 178 CYS B CB  1 
ATOM   4653  S  SG  . CYS B 2 178 ? 113.790 97.818  84.620  1.00 125.14 ? 178 CYS B SG  1 
ATOM   4654  N  N   . VAL B 2 179 ? 114.736 101.052 83.633  1.00 83.14  ? 179 VAL B N   1 
ATOM   4655  C  CA  . VAL B 2 179 ? 113.981 101.849 82.669  1.00 118.03 ? 179 VAL B CA  1 
ATOM   4656  C  C   . VAL B 2 179 ? 114.903 102.376 81.562  1.00 135.55 ? 179 VAL B C   1 
ATOM   4657  O  O   . VAL B 2 179 ? 114.556 102.347 80.388  1.00 91.65  ? 179 VAL B O   1 
ATOM   4658  C  CB  . VAL B 2 179 ? 113.245 102.988 83.407  1.00 131.03 ? 179 VAL B CB  1 
ATOM   4659  C  CG1 . VAL B 2 179 ? 112.662 104.064 82.542  1.00 119.03 ? 179 VAL B CG1 1 
ATOM   4660  C  CG2 . VAL B 2 179 ? 112.116 102.421 84.220  1.00 146.87 ? 179 VAL B CG2 1 
ATOM   4661  N  N   . LEU B 2 180 ? 116.075 102.892 81.929  1.00 145.82 ? 180 LEU B N   1 
ATOM   4662  C  CA  . LEU B 2 180 ? 117.023 103.369 80.940  1.00 124.92 ? 180 LEU B CA  1 
ATOM   4663  C  C   . LEU B 2 180 ? 117.447 102.231 80.021  1.00 94.84  ? 180 LEU B C   1 
ATOM   4664  O  O   . LEU B 2 180 ? 117.519 102.441 78.825  1.00 122.37 ? 180 LEU B O   1 
ATOM   4665  C  CB  . LEU B 2 180 ? 118.259 103.983 81.610  1.00 102.13 ? 180 LEU B CB  1 
ATOM   4666  C  CG  . LEU B 2 180 ? 118.063 105.330 82.281  1.00 156.25 ? 180 LEU B CG  1 
ATOM   4667  C  CD1 . LEU B 2 180 ? 119.335 105.603 83.078  1.00 187.11 ? 180 LEU B CD1 1 
ATOM   4668  C  CD2 . LEU B 2 180 ? 117.768 106.466 81.299  1.00 194.36 ? 180 LEU B CD2 1 
ATOM   4669  N  N   . LEU B 2 181 ? 117.745 101.052 80.545  1.00 86.75  ? 181 LEU B N   1 
ATOM   4670  C  CA  . LEU B 2 181 ? 118.233 99.972  79.706  1.00 92.09  ? 181 LEU B CA  1 
ATOM   4671  C  C   . LEU B 2 181 ? 117.128 99.534  78.754  1.00 108.16 ? 181 LEU B C   1 
ATOM   4672  O  O   . LEU B 2 181 ? 117.402 99.312  77.569  1.00 145.88 ? 181 LEU B O   1 
ATOM   4673  C  CB  . LEU B 2 181 ? 118.687 98.773  80.527  1.00 113.16 ? 181 LEU B CB  1 
ATOM   4674  C  CG  . LEU B 2 181 ? 118.958 97.495  79.735  1.00 112.36 ? 181 LEU B CG  1 
ATOM   4675  C  CD1 . LEU B 2 181 ? 120.154 97.711  78.863  1.00 237.42 ? 181 LEU B CD1 1 
ATOM   4676  C  CD2 . LEU B 2 181 ? 119.254 96.328  80.621  1.00 243.16 ? 181 LEU B CD2 1 
ATOM   4677  N  N   . LEU B 2 182 ? 115.887 99.426  79.216  1.00 95.23  ? 182 LEU B N   1 
ATOM   4678  C  CA  . LEU B 2 182 ? 114.887 98.894  78.312  1.00 117.97 ? 182 LEU B CA  1 
ATOM   4679  C  C   . LEU B 2 182 ? 114.460 99.920  77.263  1.00 121.96 ? 182 LEU B C   1 
ATOM   4680  O  O   . LEU B 2 182 ? 114.001 99.515  76.186  1.00 183.54 ? 182 LEU B O   1 
ATOM   4681  C  CB  . LEU B 2 182 ? 113.698 98.396  79.124  1.00 135.20 ? 182 LEU B CB  1 
ATOM   4682  C  CG  . LEU B 2 182 ? 114.037 97.153  79.926  1.00 143.24 ? 182 LEU B CG  1 
ATOM   4683  C  CD1 . LEU B 2 182 ? 112.903 96.843  80.885  1.00 185.35 ? 182 LEU B CD1 1 
ATOM   4684  C  CD2 . LEU B 2 182 ? 114.308 95.994  78.999  1.00 159.10 ? 182 LEU B CD2 1 
ATOM   4685  N  N   . THR B 2 183 ? 114.585 101.225 77.529  1.00 91.21  ? 183 THR B N   1 
ATOM   4686  C  CA  . THR B 2 183 ? 114.349 102.179 76.456  1.00 123.11 ? 183 THR B CA  1 
ATOM   4687  C  C   . THR B 2 183 ? 115.546 102.270 75.527  1.00 129.30 ? 183 THR B C   1 
ATOM   4688  O  O   . THR B 2 183 ? 115.378 102.787 74.428  1.00 209.66 ? 183 THR B O   1 
ATOM   4689  C  CB  . THR B 2 183 ? 113.911 103.560 76.970  1.00 141.23 ? 183 THR B CB  1 
ATOM   4690  O  OG1 . THR B 2 183 ? 114.778 104.005 78.002  1.00 133.93 ? 183 THR B OG1 1 
ATOM   4691  C  CG2 . THR B 2 183 ? 112.493 103.516 77.483  1.00 157.77 ? 183 THR B CG2 1 
ATOM   4692  N  N   . ALA B 2 184 ? 116.724 101.801 75.930  1.00 130.44 ? 184 ALA B N   1 
ATOM   4693  C  CA  . ALA B 2 184 ? 117.815 101.616 74.987  1.00 171.50 ? 184 ALA B CA  1 
ATOM   4694  C  C   . ALA B 2 184 ? 117.513 100.408 74.101  1.00 130.96 ? 184 ALA B C   1 
ATOM   4695  O  O   . ALA B 2 184 ? 117.510 100.551 72.856  1.00 243.57 ? 184 ALA B O   1 
ATOM   4696  C  CB  . ALA B 2 184 ? 119.150 101.493 75.684  1.00 191.47 ? 184 ALA B CB  1 
ATOM   4697  N  N   . VAL B 2 185 ? 117.286 99.249  74.709  1.00 87.15  ? 185 VAL B N   1 
ATOM   4698  C  CA  . VAL B 2 185 ? 116.950 98.063  73.941  1.00 124.75 ? 185 VAL B CA  1 
ATOM   4699  C  C   . VAL B 2 185 ? 115.778 98.277  72.972  1.00 121.25 ? 185 VAL B C   1 
ATOM   4700  O  O   . VAL B 2 185 ? 115.871 97.802  71.839  1.00 180.05 ? 185 VAL B O   1 
ATOM   4701  C  CB  . VAL B 2 185 ? 116.669 96.874  74.866  1.00 177.81 ? 185 VAL B CB  1 
ATOM   4702  C  CG1 . VAL B 2 185 ? 115.964 95.695  74.148  1.00 125.42 ? 185 VAL B CG1 1 
ATOM   4703  C  CG2 . VAL B 2 185 ? 117.990 96.497  75.540  1.00 176.59 ? 185 VAL B CG2 1 
ATOM   4704  N  N   . ASN B 2 186 ? 114.709 98.962  73.370  1.00 108.37 ? 186 ASN B N   1 
ATOM   4705  C  CA  . ASN B 2 186 ? 113.573 99.139  72.488  1.00 124.60 ? 186 ASN B CA  1 
ATOM   4706  C  C   . ASN B 2 186 ? 113.851 100.224 71.473  1.00 158.37 ? 186 ASN B C   1 
ATOM   4707  O  O   . ASN B 2 186 ? 113.062 100.277 70.535  1.00 275.74 ? 186 ASN B O   1 
ATOM   4708  C  CB  . ASN B 2 186 ? 112.250 99.340  73.222  1.00 137.97 ? 186 ASN B CB  1 
ATOM   4709  C  CG  . ASN B 2 186 ? 111.918 98.101  74.041  1.00 192.08 ? 186 ASN B CG  1 
ATOM   4710  O  OD1 . ASN B 2 186 ? 112.620 97.085  73.972  1.00 173.23 ? 186 ASN B OD1 1 
ATOM   4711  N  ND2 . ASN B 2 186 ? 110.864 98.164  74.846  1.00 258.39 ? 186 ASN B ND2 1 
ATOM   4712  N  N   . CYS B 2 187 ? 114.926 101.024 71.599  1.00 152.90 ? 187 CYS B N   1 
ATOM   4713  C  CA  . CYS B 2 187 ? 115.412 101.808 70.452  1.00 210.70 ? 187 CYS B CA  1 
ATOM   4714  C  C   . CYS B 2 187 ? 116.195 100.969 69.432  1.00 171.14 ? 187 CYS B C   1 
ATOM   4715  O  O   . CYS B 2 187 ? 116.084 101.233 68.244  1.00 162.59 ? 187 CYS B O   1 
ATOM   4716  C  CB  . CYS B 2 187 ? 116.216 103.022 70.898  1.00 217.84 ? 187 CYS B CB  1 
ATOM   4717  S  SG  . CYS B 2 187 ? 115.120 104.317 71.549  1.00 245.73 ? 187 CYS B SG  1 
ATOM   4718  N  N   . TYR B 2 188 ? 116.960 99.971  69.875  1.00 136.26 ? 188 TYR B N   1 
ATOM   4719  C  CA  . TYR B 2 188 ? 117.878 99.235  69.014  1.00 170.15 ? 188 TYR B CA  1 
ATOM   4720  C  C   . TYR B 2 188 ? 117.135 98.308  68.065  1.00 162.44 ? 188 TYR B C   1 
ATOM   4721  O  O   . TYR B 2 188 ? 117.533 98.271  66.894  1.00 300.74 ? 188 TYR B O   1 
ATOM   4722  C  CB  . TYR B 2 188 ? 118.967 98.462  69.773  1.00 222.42 ? 188 TYR B CB  1 
ATOM   4723  C  CG  . TYR B 2 188 ? 120.228 99.321  69.916  1.00 324.66 ? 188 TYR B CG  1 
ATOM   4724  C  CD1 . TYR B 2 188 ? 120.191 100.656 70.380  1.00 316.29 ? 188 TYR B CD1 1 
ATOM   4725  C  CD2 . TYR B 2 188 ? 121.470 98.789  69.555  1.00 303.68 ? 188 TYR B CD2 1 
ATOM   4726  C  CE1 . TYR B 2 188 ? 121.350 101.423 70.466  1.00 220.23 ? 188 TYR B CE1 1 
ATOM   4727  C  CE2 . TYR B 2 188 ? 122.636 99.543  69.660  1.00 270.55 ? 188 TYR B CE2 1 
ATOM   4728  C  CZ  . TYR B 2 188 ? 122.575 100.856 70.116  1.00 258.78 ? 188 TYR B CZ  1 
ATOM   4729  O  OH  . TYR B 2 188 ? 123.754 101.548 70.195  1.00 252.80 ? 188 TYR B OH  1 
ATOM   4730  N  N   . SER B 2 189 ? 116.099 97.587  68.505  1.00 122.73 ? 189 SER B N   1 
ATOM   4731  C  CA  . SER B 2 189 ? 115.408 96.699  67.568  1.00 185.22 ? 189 SER B CA  1 
ATOM   4732  C  C   . SER B 2 189 ? 114.165 96.064  68.150  1.00 136.58 ? 189 SER B C   1 
ATOM   4733  O  O   . SER B 2 189 ? 114.224 95.539  69.258  1.00 210.97 ? 189 SER B O   1 
ATOM   4734  C  CB  . SER B 2 189 ? 116.268 95.540  67.069  1.00 250.49 ? 189 SER B CB  1 
ATOM   4735  O  OG  . SER B 2 189 ? 115.525 94.746  66.129  1.00 264.07 ? 189 SER B OG  1 
ATOM   4736  N  N   . VAL B 2 190 ? 113.054 96.068  67.401  1.00 122.96 ? 190 VAL B N   1 
ATOM   4737  C  CA  . VAL B 2 190 ? 111.850 95.411  67.908  1.00 157.00 ? 190 VAL B CA  1 
ATOM   4738  C  C   . VAL B 2 190 ? 112.078 93.900  68.059  1.00 131.58 ? 190 VAL B C   1 
ATOM   4739  O  O   . VAL B 2 190 ? 111.415 93.266  68.887  1.00 153.86 ? 190 VAL B O   1 
ATOM   4740  C  CB  . VAL B 2 190 ? 110.604 95.766  67.072  1.00 199.58 ? 190 VAL B CB  1 
ATOM   4741  C  CG1 . VAL B 2 190 ? 109.333 95.010  67.494  1.00 204.99 ? 190 VAL B CG1 1 
ATOM   4742  C  CG2 . VAL B 2 190 ? 110.375 97.271  67.138  1.00 153.65 ? 190 VAL B CG2 1 
ATOM   4743  N  N   . LYS B 2 191 ? 113.002 93.325  67.286  1.00 127.95 ? 191 LYS B N   1 
ATOM   4744  C  CA  . LYS B 2 191 ? 113.336 91.915  67.451  1.00 229.93 ? 191 LYS B CA  1 
ATOM   4745  C  C   . LYS B 2 191 ? 114.071 91.694  68.783  1.00 217.17 ? 191 LYS B C   1 
ATOM   4746  O  O   . LYS B 2 191 ? 113.837 90.688  69.453  1.00 256.76 ? 191 LYS B O   1 
ATOM   4747  C  CB  . LYS B 2 191 ? 114.121 91.419  66.231  1.00 343.74 ? 191 LYS B CB  1 
ATOM   4748  C  CG  . LYS B 2 191 ? 114.322 89.912  66.179  1.00 430.31 ? 191 LYS B CG  1 
ATOM   4749  C  CD  . LYS B 2 191 ? 114.837 89.416  64.840  1.00 490.36 ? 191 LYS B CD  1 
ATOM   4750  C  CE  . LYS B 2 191 ? 116.236 89.897  64.509  1.00 504.51 ? 191 LYS B CE  1 
ATOM   4751  N  NZ  . LYS B 2 191 ? 116.728 89.325  63.233  1.00 504.92 ? 191 LYS B NZ  1 
ATOM   4752  N  N   . ALA B 2 192 ? 114.941 92.623  69.194  1.00 194.26 ? 192 ALA B N   1 
ATOM   4753  C  CA  . ALA B 2 192 ? 115.549 92.561  70.518  1.00 249.86 ? 192 ALA B CA  1 
ATOM   4754  C  C   . ALA B 2 192 ? 114.490 92.746  71.614  1.00 190.48 ? 192 ALA B C   1 
ATOM   4755  O  O   . ALA B 2 192 ? 114.445 91.983  72.563  1.00 174.20 ? 192 ALA B O   1 
ATOM   4756  C  CB  . ALA B 2 192 ? 116.660 93.582  70.614  1.00 334.08 ? 192 ALA B CB  1 
ATOM   4757  N  N   . ALA B 2 193 ? 113.627 93.753  71.478  1.00 169.42 ? 193 ALA B N   1 
ATOM   4758  C  CA  . ALA B 2 193 ? 112.561 94.030  72.429  1.00 166.50 ? 193 ALA B CA  1 
ATOM   4759  C  C   . ALA B 2 193 ? 111.690 92.798  72.678  1.00 139.19 ? 193 ALA B C   1 
ATOM   4760  O  O   . ALA B 2 193 ? 111.382 92.484  73.827  1.00 218.12 ? 193 ALA B O   1 
ATOM   4761  C  CB  . ALA B 2 193 ? 111.704 95.163  71.914  1.00 206.21 ? 193 ALA B CB  1 
ATOM   4762  N  N   . THR B 2 194 ? 111.268 92.113  71.617  1.00 114.86 ? 194 THR B N   1 
ATOM   4763  C  CA  . THR B 2 194 ? 110.381 90.961  71.747  1.00 169.96 ? 194 THR B CA  1 
ATOM   4764  C  C   . THR B 2 194 ? 111.141 89.693  72.164  1.00 133.53 ? 194 THR B C   1 
ATOM   4765  O  O   . THR B 2 194 ? 110.559 88.853  72.862  1.00 196.88 ? 194 THR B O   1 
ATOM   4766  C  CB  . THR B 2 194 ? 109.489 90.794  70.510  1.00 208.13 ? 194 THR B CB  1 
ATOM   4767  O  OG1 . THR B 2 194 ? 110.310 90.703  69.346  1.00 236.38 ? 194 THR B OG1 1 
ATOM   4768  C  CG2 . THR B 2 194 ? 108.500 91.939  70.395  1.00 214.88 ? 194 THR B CG2 1 
ATOM   4769  N  N   . ARG B 2 195 ? 112.413 89.553  71.806  1.00 128.76 ? 195 ARG B N   1 
ATOM   4770  C  CA  . ARG B 2 195 ? 113.221 88.477  72.376  1.00 197.27 ? 195 ARG B CA  1 
ATOM   4771  C  C   . ARG B 2 195 ? 113.436 88.649  73.896  1.00 194.36 ? 195 ARG B C   1 
ATOM   4772  O  O   . ARG B 2 195 ? 113.458 87.657  74.621  1.00 141.94 ? 195 ARG B O   1 
ATOM   4773  C  CB  . ARG B 2 195 ? 114.550 88.372  71.614  1.00 287.55 ? 195 ARG B CB  1 
ATOM   4774  C  CG  . ARG B 2 195 ? 114.426 87.691  70.257  1.00 322.55 ? 195 ARG B CG  1 
ATOM   4775  C  CD  . ARG B 2 195 ? 115.666 87.827  69.378  1.00 304.32 ? 195 ARG B CD  1 
ATOM   4776  N  NE  . ARG B 2 195 ? 116.861 87.175  69.917  1.00 356.10 ? 195 ARG B NE  1 
ATOM   4777  C  CZ  . ARG B 2 195 ? 117.166 85.875  69.814  1.00 388.69 ? 195 ARG B CZ  1 
ATOM   4778  N  NH1 . ARG B 2 195 ? 118.242 85.393  70.420  1.00 338.63 ? 195 ARG B NH1 1 
ATOM   4779  N  NH2 . ARG B 2 195 ? 116.400 85.051  69.113  1.00 405.18 ? 195 ARG B NH2 1 
ATOM   4780  N  N   . VAL B 2 196 ? 113.609 89.890  74.394  1.00 187.27 ? 196 VAL B N   1 
ATOM   4781  C  CA  . VAL B 2 196 ? 113.664 90.189  75.830  1.00 153.97 ? 196 VAL B CA  1 
ATOM   4782  C  C   . VAL B 2 196 ? 112.374 89.764  76.511  1.00 124.91 ? 196 VAL B C   1 
ATOM   4783  O  O   . VAL B 2 196 ? 112.421 89.089  77.524  1.00 145.32 ? 196 VAL B O   1 
ATOM   4784  C  CB  . VAL B 2 196 ? 113.962 91.673  76.133  1.00 147.55 ? 196 VAL B CB  1 
ATOM   4785  C  CG1 . VAL B 2 196 ? 113.680 92.072  77.571  1.00 138.44 ? 196 VAL B CG1 1 
ATOM   4786  C  CG2 . VAL B 2 196 ? 115.412 91.973  75.823  1.00 239.40 ? 196 VAL B CG2 1 
ATOM   4787  N  N   . GLN B 2 197 ? 111.226 90.132  75.961  1.00 136.80 ? 197 GLN B N   1 
ATOM   4788  C  CA  . GLN B 2 197 ? 109.979 89.731  76.591  1.00 155.12 ? 197 GLN B CA  1 
ATOM   4789  C  C   . GLN B 2 197 ? 109.660 88.233  76.428  1.00 136.33 ? 197 GLN B C   1 
ATOM   4790  O  O   . GLN B 2 197 ? 109.013 87.700  77.312  1.00 130.65 ? 197 GLN B O   1 
ATOM   4791  C  CB  . GLN B 2 197 ? 108.839 90.599  76.080  1.00 145.59 ? 197 GLN B CB  1 
ATOM   4792  C  CG  . GLN B 2 197 ? 107.559 90.305  76.778  1.00 121.78 ? 197 GLN B CG  1 
ATOM   4793  C  CD  . GLN B 2 197 ? 106.634 91.463  76.912  1.00 176.34 ? 197 GLN B CD  1 
ATOM   4794  O  OE1 . GLN B 2 197 ? 105.877 91.529  77.882  1.00 227.95 ? 197 GLN B OE1 1 
ATOM   4795  N  NE2 . GLN B 2 197 ? 106.662 92.362  75.938  1.00 209.54 ? 197 GLN B NE2 1 
ATOM   4796  N  N   . ASP B 2 198 ? 110.100 87.538  75.375  1.00 113.26 ? 198 ASP B N   1 
ATOM   4797  C  CA  . ASP B 2 198 ? 110.024 86.094  75.381  1.00 168.56 ? 198 ASP B CA  1 
ATOM   4798  C  C   . ASP B 2 198 ? 110.765 85.533  76.605  1.00 173.00 ? 198 ASP B C   1 
ATOM   4799  O  O   . ASP B 2 198 ? 110.220 84.694  77.338  1.00 160.34 ? 198 ASP B O   1 
ATOM   4800  C  CB  . ASP B 2 198 ? 110.520 85.517  74.044  1.00 317.06 ? 198 ASP B CB  1 
ATOM   4801  C  CG  . ASP B 2 198 ? 110.589 83.991  74.002  1.00 440.98 ? 198 ASP B CG  1 
ATOM   4802  O  OD1 . ASP B 2 198 ? 109.627 83.339  74.476  1.00 446.69 ? 198 ASP B OD1 1 
ATOM   4803  O  OD2 . ASP B 2 198 ? 111.603 83.457  73.490  1.00 469.76 ? 198 ASP B OD2 1 
ATOM   4804  N  N   . ALA B 2 199 ? 112.010 85.991  76.818  1.00 178.29 ? 199 ALA B N   1 
ATOM   4805  C  CA  . ALA B 2 199 ? 112.881 85.517  77.897  1.00 221.54 ? 199 ALA B CA  1 
ATOM   4806  C  C   . ALA B 2 199 ? 112.236 85.711  79.265  1.00 149.77 ? 199 ALA B C   1 
ATOM   4807  O  O   . ALA B 2 199 ? 112.231 84.797  80.081  1.00 149.38 ? 199 ALA B O   1 
ATOM   4808  C  CB  . ALA B 2 199 ? 114.244 86.205  77.844  1.00 214.54 ? 199 ALA B CB  1 
ATOM   4809  N  N   . PHE B 2 200 ? 111.703 86.905  79.522  1.00 152.35 ? 200 PHE B N   1 
ATOM   4810  C  CA  . PHE B 2 200 ? 111.156 87.190  80.837  1.00 145.16 ? 200 PHE B CA  1 
ATOM   4811  C  C   . PHE B 2 200 ? 109.730 86.674  80.996  1.00 137.75 ? 200 PHE B C   1 
ATOM   4812  O  O   . PHE B 2 200 ? 109.398 86.280  82.112  1.00 224.74 ? 200 PHE B O   1 
ATOM   4813  C  CB  . PHE B 2 200 ? 111.363 88.661  81.186  1.00 178.63 ? 200 PHE B CB  1 
ATOM   4814  C  CG  . PHE B 2 200 ? 112.830 88.915  81.408  1.00 157.17 ? 200 PHE B CG  1 
ATOM   4815  C  CD1 . PHE B 2 200 ? 113.520 88.264  82.434  1.00 181.36 ? 200 PHE B CD1 1 
ATOM   4816  C  CD2 . PHE B 2 200 ? 113.506 89.759  80.570  1.00 131.01 ? 200 PHE B CD2 1 
ATOM   4817  C  CE1 . PHE B 2 200 ? 114.868 88.465  82.622  1.00 184.71 ? 200 PHE B CE1 1 
ATOM   4818  C  CE2 . PHE B 2 200 ? 114.862 89.953  80.758  1.00 220.10 ? 200 PHE B CE2 1 
ATOM   4819  C  CZ  . PHE B 2 200 ? 115.537 89.317  81.783  1.00 241.29 ? 200 PHE B CZ  1 
ATOM   4820  N  N   . ALA B 2 201 ? 108.896 86.627  79.956  1.00 167.36 ? 201 ALA B N   1 
ATOM   4821  C  CA  . ALA B 2 201 ? 107.631 85.892  80.042  1.00 188.06 ? 201 ALA B CA  1 
ATOM   4822  C  C   . ALA B 2 201 ? 107.867 84.417  80.414  1.00 194.26 ? 201 ALA B C   1 
ATOM   4823  O  O   . ALA B 2 201 ? 107.108 83.828  81.176  1.00 176.79 ? 201 ALA B O   1 
ATOM   4824  C  CB  . ALA B 2 201 ? 106.873 86.010  78.748  1.00 242.57 ? 201 ALA B CB  1 
ATOM   4825  N  N   . ALA B 2 202 ? 108.935 83.810  79.885  1.00 193.31 ? 202 ALA B N   1 
ATOM   4826  C  CA  . ALA B 2 202 ? 109.311 82.459  80.248  1.00 225.85 ? 202 ALA B CA  1 
ATOM   4827  C  C   . ALA B 2 202 ? 109.739 82.397  81.712  1.00 167.15 ? 202 ALA B C   1 
ATOM   4828  O  O   . ALA B 2 202 ? 109.306 81.504  82.414  1.00 144.34 ? 202 ALA B O   1 
ATOM   4829  C  CB  . ALA B 2 202 ? 110.398 81.955  79.315  1.00 324.26 ? 202 ALA B CB  1 
ATOM   4830  N  N   . ALA B 2 203 ? 110.586 83.321  82.177  1.00 181.76 ? 203 ALA B N   1 
ATOM   4831  C  CA  . ALA B 2 203 ? 111.032 83.341  83.567  1.00 199.05 ? 203 ALA B CA  1 
ATOM   4832  C  C   . ALA B 2 203 ? 109.845 83.385  84.538  1.00 158.63 ? 203 ALA B C   1 
ATOM   4833  O  O   . ALA B 2 203 ? 109.846 82.691  85.555  1.00 193.62 ? 203 ALA B O   1 
ATOM   4834  C  CB  . ALA B 2 203 ? 111.978 84.506  83.781  1.00 223.71 ? 203 ALA B CB  1 
ATOM   4835  N  N   . LYS B 2 204 ? 108.825 84.181  84.212  1.00 154.27 ? 204 LYS B N   1 
ATOM   4836  C  CA  . LYS B 2 204 ? 107.608 84.284  85.006  1.00 160.35 ? 204 LYS B CA  1 
ATOM   4837  C  C   . LYS B 2 204 ? 106.863 82.960  85.103  1.00 165.99 ? 204 LYS B C   1 
ATOM   4838  O  O   . LYS B 2 204 ? 106.584 82.535  86.210  1.00 219.30 ? 204 LYS B O   1 
ATOM   4839  C  CB  . LYS B 2 204 ? 106.663 85.322  84.414  1.00 135.00 ? 204 LYS B CB  1 
ATOM   4840  C  CG  . LYS B 2 204 ? 107.261 86.704  84.465  1.00 166.17 ? 204 LYS B CG  1 
ATOM   4841  C  CD  . LYS B 2 204 ? 106.635 87.727  83.593  1.00 185.57 ? 204 LYS B CD  1 
ATOM   4842  C  CE  . LYS B 2 204 ? 105.427 88.259  84.273  1.00 162.61 ? 204 LYS B CE  1 
ATOM   4843  N  NZ  . LYS B 2 204 ? 105.755 89.140  85.414  1.00 198.72 ? 204 LYS B NZ  1 
ATOM   4844  N  N   . LEU B 2 205 ? 106.561 82.311  83.979  1.00 154.09 ? 205 LEU B N   1 
ATOM   4845  C  CA  . LEU B 2 205 ? 105.777 81.086  84.024  1.00 166.85 ? 205 LEU B CA  1 
ATOM   4846  C  C   . LEU B 2 205 ? 106.605 79.969  84.644  1.00 180.23 ? 205 LEU B C   1 
ATOM   4847  O  O   . LEU B 2 205 ? 106.019 79.144  85.323  1.00 166.23 ? 205 LEU B O   1 
ATOM   4848  C  CB  . LEU B 2 205 ? 105.290 80.708  82.622  1.00 194.96 ? 205 LEU B CB  1 
ATOM   4849  C  CG  . LEU B 2 205 ? 104.235 81.627  82.017  1.00 209.94 ? 205 LEU B CG  1 
ATOM   4850  C  CD1 . LEU B 2 205 ? 103.783 81.074  80.680  1.00 222.60 ? 205 LEU B CD1 1 
ATOM   4851  C  CD2 . LEU B 2 205 ? 103.034 81.832  82.936  1.00 176.56 ? 205 LEU B CD2 1 
ATOM   4852  N  N   . LEU B 2 206 ? 107.935 79.946  84.427  1.00 219.02 ? 206 LEU B N   1 
ATOM   4853  C  CA  . LEU B 2 206 ? 108.836 78.990  85.072  1.00 249.61 ? 206 LEU B CA  1 
ATOM   4854  C  C   . LEU B 2 206 ? 108.774 79.132  86.596  1.00 177.63 ? 206 LEU B C   1 
ATOM   4855  O  O   . LEU B 2 206 ? 108.672 78.130  87.301  1.00 170.90 ? 206 LEU B O   1 
ATOM   4856  C  CB  . LEU B 2 206 ? 110.262 79.193  84.542  1.00 262.39 ? 206 LEU B CB  1 
ATOM   4857  C  CG  . LEU B 2 206 ? 111.368 78.386  85.219  1.00 315.44 ? 206 LEU B CG  1 
ATOM   4858  C  CD1 . LEU B 2 206 ? 111.139 76.889  85.051  1.00 397.17 ? 206 LEU B CD1 1 
ATOM   4859  C  CD2 . LEU B 2 206 ? 112.711 78.802  84.650  1.00 326.16 ? 206 LEU B CD2 1 
ATOM   4860  N  N   . ALA B 2 207 ? 108.810 80.373  87.084  1.00 182.12 ? 207 ALA B N   1 
ATOM   4861  C  CA  . ALA B 2 207 ? 108.694 80.642  88.504  1.00 191.49 ? 207 ALA B CA  1 
ATOM   4862  C  C   . ALA B 2 207 ? 107.349 80.146  89.038  1.00 147.46 ? 207 ALA B C   1 
ATOM   4863  O  O   . ALA B 2 207 ? 107.346 79.533  90.104  1.00 197.60 ? 207 ALA B O   1 
ATOM   4864  C  CB  . ALA B 2 207 ? 108.903 82.110  88.773  1.00 219.63 ? 207 ALA B CB  1 
ATOM   4865  N  N   . LEU B 2 208 ? 106.229 80.374  88.336  1.00 119.29 ? 208 LEU B N   1 
ATOM   4866  C  CA  . LEU B 2 208 ? 104.933 79.881  88.808  1.00 179.85 ? 208 LEU B CA  1 
ATOM   4867  C  C   . LEU B 2 208 ? 104.834 78.357  88.723  1.00 183.17 ? 208 LEU B C   1 
ATOM   4868  O  O   . LEU B 2 208 ? 104.214 77.747  89.588  1.00 165.47 ? 208 LEU B O   1 
ATOM   4869  C  CB  . LEU B 2 208 ? 103.782 80.576  88.065  1.00 158.09 ? 208 LEU B CB  1 
ATOM   4870  C  CG  . LEU B 2 208 ? 103.747 82.088  88.265  1.00 163.97 ? 208 LEU B CG  1 
ATOM   4871  C  CD1 . LEU B 2 208 ? 102.584 82.726  87.541  1.00 191.12 ? 208 LEU B CD1 1 
ATOM   4872  C  CD2 . LEU B 2 208 ? 103.638 82.436  89.720  1.00 222.49 ? 208 LEU B CD2 1 
ATOM   4873  N  N   . ALA B 2 209 ? 105.446 77.739  87.716  1.00 218.04 ? 209 ALA B N   1 
ATOM   4874  C  CA  . ALA B 2 209 ? 105.484 76.286  87.646  1.00 299.92 ? 209 ALA B CA  1 
ATOM   4875  C  C   . ALA B 2 209 ? 106.245 75.720  88.848  1.00 206.91 ? 209 ALA B C   1 
ATOM   4876  O  O   . ALA B 2 209 ? 105.816 74.716  89.415  1.00 205.16 ? 209 ALA B O   1 
ATOM   4877  C  CB  . ALA B 2 209 ? 106.086 75.838  86.331  1.00 404.91 ? 209 ALA B CB  1 
ATOM   4878  N  N   . LEU B 2 210 ? 107.364 76.351  89.228  1.00 158.05 ? 210 LEU B N   1 
ATOM   4879  C  CA  . LEU B 2 210 ? 108.166 75.897  90.356  1.00 171.14 ? 210 LEU B CA  1 
ATOM   4880  C  C   . LEU B 2 210 ? 107.344 76.013  91.633  1.00 135.41 ? 210 LEU B C   1 
ATOM   4881  O  O   . LEU B 2 210 ? 107.363 75.096  92.446  1.00 208.49 ? 210 LEU B O   1 
ATOM   4882  C  CB  . LEU B 2 210 ? 109.448 76.741  90.397  1.00 244.36 ? 210 LEU B CB  1 
ATOM   4883  C  CG  . LEU B 2 210 ? 110.566 76.332  91.359  1.00 210.42 ? 210 LEU B CG  1 
ATOM   4884  C  CD1 . LEU B 2 210 ? 111.884 76.984  90.912  1.00 246.28 ? 210 LEU B CD1 1 
ATOM   4885  C  CD2 . LEU B 2 210 ? 110.230 76.710  92.805  1.00 155.63 ? 210 LEU B CD2 1 
ATOM   4886  N  N   . ILE B 2 211 ? 106.619 77.119  91.795  1.00 129.36 ? 211 ILE B N   1 
ATOM   4887  C  CA  . ILE B 2 211 ? 105.729 77.328  92.937  1.00 172.44 ? 211 ILE B CA  1 
ATOM   4888  C  C   . ILE B 2 211 ? 104.655 76.237  92.967  1.00 185.07 ? 211 ILE B C   1 
ATOM   4889  O  O   . ILE B 2 211 ? 104.414 75.658  94.025  1.00 241.32 ? 211 ILE B O   1 
ATOM   4890  C  CB  . ILE B 2 211 ? 105.126 78.761  92.917  1.00 199.78 ? 211 ILE B CB  1 
ATOM   4891  C  CG1 . ILE B 2 211 ? 106.220 79.844  93.122  1.00 210.11 ? 211 ILE B CG1 1 
ATOM   4892  C  CG2 . ILE B 2 211 ? 103.897 78.924  93.848  1.00 121.68 ? 211 ILE B CG2 1 
ATOM   4893  C  CD1 . ILE B 2 211 ? 106.953 79.867  94.452  1.00 241.90 ? 211 ILE B CD1 1 
ATOM   4894  N  N   . ILE B 2 212 ? 104.016 75.945  91.822  1.00 168.98 ? 212 ILE B N   1 
ATOM   4895  C  CA  . ILE B 2 212 ? 102.928 74.979  91.779  1.00 192.41 ? 212 ILE B CA  1 
ATOM   4896  C  C   . ILE B 2 212 ? 103.464 73.580  92.109  1.00 189.34 ? 212 ILE B C   1 
ATOM   4897  O  O   . ILE B 2 212 ? 102.831 72.834  92.870  1.00 215.63 ? 212 ILE B O   1 
ATOM   4898  C  CB  . ILE B 2 212 ? 102.189 75.060  90.425  1.00 214.55 ? 212 ILE B CB  1 
ATOM   4899  C  CG1 . ILE B 2 212 ? 101.397 76.354  90.325  1.00 222.13 ? 212 ILE B CG1 1 
ATOM   4900  C  CG2 . ILE B 2 212 ? 101.271 73.867  90.193  1.00 277.51 ? 212 ILE B CG2 1 
ATOM   4901  C  CD1 . ILE B 2 212 ? 101.017 76.744  88.920  1.00 281.67 ? 212 ILE B CD1 1 
ATOM   4902  N  N   . LEU B 2 213 ? 104.625 73.236  91.536  1.00 204.76 ? 213 LEU B N   1 
ATOM   4903  C  CA  . LEU B 2 213 ? 105.242 71.928  91.724  1.00 247.27 ? 213 LEU B CA  1 
ATOM   4904  C  C   . LEU B 2 213 ? 105.532 71.669  93.211  1.00 201.99 ? 213 LEU B C   1 
ATOM   4905  O  O   . LEU B 2 213 ? 105.162 70.617  93.723  1.00 180.79 ? 213 LEU B O   1 
ATOM   4906  C  CB  . LEU B 2 213 ? 106.496 71.869  90.840  1.00 284.08 ? 213 LEU B CB  1 
ATOM   4907  C  CG  . LEU B 2 213 ? 107.212 70.523  90.754  1.00 347.21 ? 213 LEU B CG  1 
ATOM   4908  C  CD1 . LEU B 2 213 ? 107.875 70.367  89.390  1.00 402.96 ? 213 LEU B CD1 1 
ATOM   4909  C  CD2 . LEU B 2 213 ? 108.256 70.352  91.856  1.00 343.94 ? 213 LEU B CD2 1 
ATOM   4910  N  N   . LEU B 2 214 ? 106.183 72.616  93.905  1.00 186.70 ? 214 LEU B N   1 
ATOM   4911  C  CA  . LEU B 2 214 ? 106.463 72.467  95.329  1.00 142.13 ? 214 LEU B CA  1 
ATOM   4912  C  C   . LEU B 2 214 ? 105.160 72.330  96.122  1.00 183.86 ? 214 LEU B C   1 
ATOM   4913  O  O   . LEU B 2 214 ? 105.142 71.585  97.102  1.00 316.80 ? 214 LEU B O   1 
ATOM   4914  C  CB  . LEU B 2 214 ? 107.343 73.626  95.831  1.00 189.87 ? 214 LEU B CB  1 
ATOM   4915  C  CG  . LEU B 2 214 ? 108.856 73.376  95.807  1.00 249.15 ? 214 LEU B CG  1 
ATOM   4916  C  CD1 . LEU B 2 214 ? 109.255 72.273  96.778  1.00 304.77 ? 214 LEU B CD1 1 
ATOM   4917  C  CD2 . LEU B 2 214 ? 109.364 73.017  94.413  1.00 254.89 ? 214 LEU B CD2 1 
ATOM   4918  N  N   . GLY B 2 215 ? 104.073 73.007  95.712  1.00 182.11 ? 215 GLY B N   1 
ATOM   4919  C  CA  . GLY B 2 215 ? 102.752 72.813  96.304  1.00 207.42 ? 215 GLY B CA  1 
ATOM   4920  C  C   . GLY B 2 215 ? 102.269 71.364  96.238  1.00 253.44 ? 215 GLY B C   1 
ATOM   4921  O  O   . GLY B 2 215 ? 101.880 70.794  97.261  1.00 291.83 ? 215 GLY B O   1 
ATOM   4922  N  N   . PHE B 2 216 ? 102.324 70.759  95.044  1.00 238.52 ? 216 PHE B N   1 
ATOM   4923  C  CA  . PHE B 2 216 ? 101.937 69.359  94.888  1.00 268.46 ? 216 PHE B CA  1 
ATOM   4924  C  C   . PHE B 2 216 ? 102.873 68.412  95.652  1.00 236.93 ? 216 PHE B C   1 
ATOM   4925  O  O   . PHE B 2 216 ? 102.387 67.437  96.233  1.00 224.99 ? 216 PHE B O   1 
ATOM   4926  C  CB  . PHE B 2 216 ? 101.816 68.987  93.405  1.00 285.02 ? 216 PHE B CB  1 
ATOM   4927  C  CG  . PHE B 2 216 ? 100.634 69.622  92.714  1.00 318.06 ? 216 PHE B CG  1 
ATOM   4928  C  CD1 . PHE B 2 216 ? 99.356  69.562  93.267  1.00 322.35 ? 216 PHE B CD1 1 
ATOM   4929  C  CD2 . PHE B 2 216 ? 100.789 70.277  91.500  1.00 403.98 ? 216 PHE B CD2 1 
ATOM   4930  C  CE1 . PHE B 2 216 ? 98.271  70.145  92.631  1.00 332.23 ? 216 PHE B CE1 1 
ATOM   4931  C  CE2 . PHE B 2 216 ? 99.701  70.862  90.865  1.00 448.70 ? 216 PHE B CE2 1 
ATOM   4932  C  CZ  . PHE B 2 216 ? 98.445  70.794  91.431  1.00 402.84 ? 216 PHE B CZ  1 
ATOM   4933  N  N   . VAL B 2 217 ? 104.185 68.697  95.664  1.00 209.19 ? 217 VAL B N   1 
ATOM   4934  C  CA  . VAL B 2 217 ? 105.140 67.933  96.462  1.00 197.21 ? 217 VAL B CA  1 
ATOM   4935  C  C   . VAL B 2 217 ? 104.751 67.961  97.946  1.00 174.86 ? 217 VAL B C   1 
ATOM   4936  O  O   . VAL B 2 217 ? 104.853 66.926  98.606  1.00 282.03 ? 217 VAL B O   1 
ATOM   4937  C  CB  . VAL B 2 217 ? 106.593 68.411  96.204  1.00 214.78 ? 217 VAL B CB  1 
ATOM   4938  C  CG1 . VAL B 2 217 ? 107.613 68.044  97.288  1.00 184.74 ? 217 VAL B CG1 1 
ATOM   4939  C  CG2 . VAL B 2 217 ? 107.071 67.904  94.854  1.00 258.59 ? 217 VAL B CG2 1 
ATOM   4940  N  N   . GLN B 2 218 ? 104.319 69.111  98.477  1.00 192.26 ? 218 GLN B N   1 
ATOM   4941  C  CA  . GLN B 2 218 ? 103.913 69.204  99.875  1.00 237.59 ? 218 GLN B CA  1 
ATOM   4942  C  C   . GLN B 2 218 ? 102.638 68.388  100.128 1.00 274.61 ? 218 GLN B C   1 
ATOM   4943  O  O   . GLN B 2 218 ? 102.505 67.813  101.207 1.00 370.96 ? 218 GLN B O   1 
ATOM   4944  C  CB  . GLN B 2 218 ? 103.774 70.666  100.311 1.00 224.30 ? 218 GLN B CB  1 
ATOM   4945  C  CG  . GLN B 2 218 ? 103.565 70.868  101.809 1.00 250.87 ? 218 GLN B CG  1 
ATOM   4946  C  CD  . GLN B 2 218 ? 104.653 70.332  102.717 1.00 372.50 ? 218 GLN B CD  1 
ATOM   4947  O  OE1 . GLN B 2 218 ? 105.786 70.076  102.305 1.00 435.80 ? 218 GLN B OE1 1 
ATOM   4948  N  NE2 . GLN B 2 218 ? 104.307 70.155  103.985 1.00 391.30 ? 218 GLN B NE2 1 
ATOM   4949  N  N   . ILE B 2 219 ? 101.706 68.312  99.164  1.00 234.17 ? 219 ILE B N   1 
ATOM   4950  C  CA  . ILE B 2 219 ? 100.570 67.402  99.308  1.00 271.96 ? 219 ILE B CA  1 
ATOM   4951  C  C   . ILE B 2 219 ? 101.058 65.939  99.321  1.00 280.51 ? 219 ILE B C   1 
ATOM   4952  O  O   . ILE B 2 219 ? 100.601 65.158  100.161 1.00 317.01 ? 219 ILE B O   1 
ATOM   4953  C  CB  . ILE B 2 219 ? 99.481  67.697  98.254  1.00 278.40 ? 219 ILE B CB  1 
ATOM   4954  C  CG1 . ILE B 2 219 ? 98.844  69.068  98.492  1.00 271.48 ? 219 ILE B CG1 1 
ATOM   4955  C  CG2 . ILE B 2 219 ? 98.411  66.606  98.243  1.00 289.30 ? 219 ILE B CG2 1 
ATOM   4956  C  CD1 . ILE B 2 219 ? 98.062  69.601  97.316  1.00 322.05 ? 219 ILE B CD1 1 
ATOM   4957  N  N   . GLY B 2 220 ? 101.988 65.573  98.421  1.00 257.11 ? 220 GLY B N   1 
ATOM   4958  C  CA  . GLY B 2 220 ? 102.605 64.244  98.381  1.00 283.72 ? 220 GLY B CA  1 
ATOM   4959  C  C   . GLY B 2 220 ? 103.309 63.812  99.678  1.00 328.80 ? 220 GLY B C   1 
ATOM   4960  O  O   . GLY B 2 220 ? 103.330 62.627  100.002 1.00 310.10 ? 220 GLY B O   1 
ATOM   4961  N  N   . LYS B 2 221 ? 103.884 64.776  100.420 1.00 391.31 ? 221 LYS B N   1 
ATOM   4962  C  CA  . LYS B 2 221 ? 104.470 64.560  101.742 1.00 397.05 ? 221 LYS B CA  1 
ATOM   4963  C  C   . LYS B 2 221 ? 103.433 64.550  102.882 1.00 358.30 ? 221 LYS B C   1 
ATOM   4964  O  O   . LYS B 2 221 ? 103.808 64.425  104.051 1.00 218.08 ? 221 LYS B O   1 
ATOM   4965  C  CB  . LYS B 2 221 ? 105.497 65.664  102.023 1.00 413.97 ? 221 LYS B CB  1 
ATOM   4966  C  CG  . LYS B 2 221 ? 106.767 65.613  101.182 1.00 389.25 ? 221 LYS B CG  1 
ATOM   4967  C  CD  . LYS B 2 221 ? 107.514 66.939  101.134 1.00 370.73 ? 221 LYS B CD  1 
ATOM   4968  C  CE  . LYS B 2 221 ? 108.073 67.427  102.455 1.00 331.51 ? 221 LYS B CE  1 
ATOM   4969  N  NZ  . LYS B 2 221 ? 108.448 68.861  102.372 1.00 292.33 ? 221 LYS B NZ  1 
ATOM   4970  N  N   . GLY B 2 222 ? 102.132 64.727  102.587 1.00 399.91 ? 222 GLY B N   1 
ATOM   4971  C  CA  . GLY B 2 222 ? 101.061 64.453  103.542 1.00 389.94 ? 222 GLY B CA  1 
ATOM   4972  C  C   . GLY B 2 222 ? 100.870 65.572  104.552 1.00 338.29 ? 222 GLY B C   1 
ATOM   4973  O  O   . GLY B 2 222 ? 99.682  65.784  104.936 1.00 218.74 ? 222 GLY B O   1 
ATOM   4974  N  N   . PHE B 2 233 ? 86.837  74.572  102.656 1.00 276.99 ? 233 PHE B N   1 
ATOM   4975  C  CA  . PHE B 2 233 ? 86.276  75.875  103.127 1.00 296.43 ? 233 PHE B CA  1 
ATOM   4976  C  C   . PHE B 2 233 ? 86.400  76.007  104.644 1.00 283.81 ? 233 PHE B C   1 
ATOM   4977  O  O   . PHE B 2 233 ? 86.311  75.018  105.370 1.00 347.82 ? 233 PHE B O   1 
ATOM   4978  C  CB  . PHE B 2 233 ? 84.808  76.071  102.711 1.00 314.82 ? 233 PHE B CB  1 
ATOM   4979  C  CG  . PHE B 2 233 ? 84.608  76.394  101.249 1.00 410.20 ? 233 PHE B CG  1 
ATOM   4980  C  CD1 . PHE B 2 233 ? 84.782  75.413  100.276 1.00 429.00 ? 233 PHE B CD1 1 
ATOM   4981  C  CD2 . PHE B 2 233 ? 84.254  77.681  100.836 1.00 420.58 ? 233 PHE B CD2 1 
ATOM   4982  C  CE1 . PHE B 2 233 ? 84.602  75.707  98.928  1.00 412.93 ? 233 PHE B CE1 1 
ATOM   4983  C  CE2 . PHE B 2 233 ? 84.078  77.974  99.489  1.00 419.04 ? 233 PHE B CE2 1 
ATOM   4984  C  CZ  . PHE B 2 233 ? 84.250  76.986  98.538  1.00 436.27 ? 233 PHE B CZ  1 
ATOM   4985  N  N   . GLU B 2 234 ? 86.601  77.260  105.089 1.00 293.58 ? 234 GLU B N   1 
ATOM   4986  C  CA  . GLU B 2 234 ? 86.749  77.658  106.488 1.00 345.25 ? 234 GLU B CA  1 
ATOM   4987  C  C   . GLU B 2 234 ? 85.832  78.871  106.750 1.00 325.01 ? 234 GLU B C   1 
ATOM   4988  O  O   . GLU B 2 234 ? 84.983  79.205  105.913 1.00 265.97 ? 234 GLU B O   1 
ATOM   4989  C  CB  . GLU B 2 234 ? 88.237  77.940  106.771 1.00 431.98 ? 234 GLU B CB  1 
ATOM   4990  C  CG  . GLU B 2 234 ? 89.180  76.757  106.548 1.00 475.07 ? 234 GLU B CG  1 
ATOM   4991  C  CD  . GLU B 2 234 ? 89.048  75.570  107.491 1.00 489.94 ? 234 GLU B CD  1 
ATOM   4992  O  OE1 . GLU B 2 234 ? 88.405  75.718  108.554 1.00 512.87 ? 234 GLU B OE1 1 
ATOM   4993  O  OE2 . GLU B 2 234 ? 89.590  74.494  107.151 1.00 451.76 ? 234 GLU B OE2 1 
ATOM   4994  N  N   . GLY B 2 235 ? 85.994  79.533  107.916 1.00 340.37 ? 235 GLY B N   1 
ATOM   4995  C  CA  . GLY B 2 235 ? 85.254  80.736  108.292 1.00 350.95 ? 235 GLY B CA  1 
ATOM   4996  C  C   . GLY B 2 235 ? 85.231  81.818  107.208 1.00 297.42 ? 235 GLY B C   1 
ATOM   4997  O  O   . GLY B 2 235 ? 86.258  82.444  106.939 1.00 247.26 ? 235 GLY B O   1 
ATOM   4998  N  N   . THR B 2 236 ? 84.044  82.017  106.602 1.00 278.86 ? 236 THR B N   1 
ATOM   4999  C  CA  . THR B 2 236 ? 83.864  82.760  105.358 1.00 265.50 ? 236 THR B CA  1 
ATOM   5000  C  C   . THR B 2 236 ? 83.178  84.105  105.624 1.00 292.16 ? 236 THR B C   1 
ATOM   5001  O  O   . THR B 2 236 ? 82.154  84.145  106.309 1.00 256.06 ? 236 THR B O   1 
ATOM   5002  C  CB  . THR B 2 236 ? 83.064  81.909  104.358 1.00 246.35 ? 236 THR B CB  1 
ATOM   5003  O  OG1 . THR B 2 236 ? 83.805  80.729  104.035 1.00 245.08 ? 236 THR B OG1 1 
ATOM   5004  C  CG2 . THR B 2 236 ? 82.734  82.637  103.067 1.00 273.28 ? 236 THR B CG2 1 
ATOM   5005  N  N   . LYS B 2 237 ? 83.733  85.198  105.065 1.00 369.36 ? 237 LYS B N   1 
ATOM   5006  C  CA  . LYS B 2 237 ? 83.138  86.531  105.169 1.00 357.21 ? 237 LYS B CA  1 
ATOM   5007  C  C   . LYS B 2 237 ? 82.013  86.674  104.134 1.00 344.60 ? 237 LYS B C   1 
ATOM   5008  O  O   . LYS B 2 237 ? 82.155  87.397  103.149 1.00 385.81 ? 237 LYS B O   1 
ATOM   5009  C  CB  . LYS B 2 237 ? 84.238  87.594  105.022 1.00 367.71 ? 237 LYS B CB  1 
ATOM   5010  C  CG  . LYS B 2 237 ? 85.272  87.544  106.138 1.00 345.07 ? 237 LYS B CG  1 
ATOM   5011  C  CD  . LYS B 2 237 ? 86.313  88.637  106.089 1.00 364.50 ? 237 LYS B CD  1 
ATOM   5012  C  CE  . LYS B 2 237 ? 87.327  88.484  107.204 1.00 396.25 ? 237 LYS B CE  1 
ATOM   5013  N  NZ  . LYS B 2 237 ? 88.298  89.602  107.251 1.00 423.17 ? 237 LYS B NZ  1 
ATOM   5014  N  N   . LEU B 2 238 ? 80.880  85.992  104.382 1.00 304.02 ? 238 LEU B N   1 
ATOM   5015  C  CA  . LEU B 2 238 ? 79.858  85.695  103.374 1.00 310.70 ? 238 LEU B CA  1 
ATOM   5016  C  C   . LEU B 2 238 ? 78.962  86.902  103.024 1.00 294.87 ? 238 LEU B C   1 
ATOM   5017  O  O   . LEU B 2 238 ? 78.074  86.781  102.175 1.00 249.79 ? 238 LEU B O   1 
ATOM   5018  C  CB  . LEU B 2 238 ? 79.036  84.509  103.908 1.00 389.17 ? 238 LEU B CB  1 
ATOM   5019  C  CG  . LEU B 2 238 ? 78.049  83.812  102.964 1.00 446.55 ? 238 LEU B CG  1 
ATOM   5020  C  CD1 . LEU B 2 238 ? 78.708  83.355  101.669 1.00 424.43 ? 238 LEU B CD1 1 
ATOM   5021  C  CD2 . LEU B 2 238 ? 77.407  82.622  103.663 1.00 472.12 ? 238 LEU B CD2 1 
ATOM   5022  N  N   . ASP B 2 239 ? 79.180  88.069  103.651 1.00 326.45 ? 239 ASP B N   1 
ATOM   5023  C  CA  . ASP B 2 239 ? 78.592  89.344  103.242 1.00 354.75 ? 239 ASP B CA  1 
ATOM   5024  C  C   . ASP B 2 239 ? 78.930  89.710  101.788 1.00 409.97 ? 239 ASP B C   1 
ATOM   5025  O  O   . ASP B 2 239 ? 80.099  89.705  101.408 1.00 511.74 ? 239 ASP B O   1 
ATOM   5026  C  CB  . ASP B 2 239 ? 79.072  90.444  104.202 1.00 403.50 ? 239 ASP B CB  1 
ATOM   5027  C  CG  . ASP B 2 239 ? 78.808  91.878  103.769 1.00 417.68 ? 239 ASP B CG  1 
ATOM   5028  O  OD1 . ASP B 2 239 ? 77.767  92.121  103.124 1.00 397.88 ? 239 ASP B OD1 1 
ATOM   5029  O  OD2 . ASP B 2 239 ? 79.651  92.748  104.083 1.00 445.62 ? 239 ASP B OD2 1 
ATOM   5030  N  N   . VAL B 2 240 ? 77.912  90.068  100.981 1.00 381.76 ? 240 VAL B N   1 
ATOM   5031  C  CA  . VAL B 2 240 ? 78.109  90.535  99.605  1.00 387.18 ? 240 VAL B CA  1 
ATOM   5032  C  C   . VAL B 2 240 ? 79.042  91.760  99.565  1.00 412.02 ? 240 VAL B C   1 
ATOM   5033  O  O   . VAL B 2 240 ? 79.864  91.864  98.649  1.00 455.97 ? 240 VAL B O   1 
ATOM   5034  C  CB  . VAL B 2 240 ? 76.752  90.796  98.906  1.00 362.85 ? 240 VAL B CB  1 
ATOM   5035  C  CG1 . VAL B 2 240 ? 76.876  91.511  97.562  1.00 337.60 ? 240 VAL B CG1 1 
ATOM   5036  C  CG2 . VAL B 2 240 ? 75.973  89.500  98.725  1.00 373.96 ? 240 VAL B CG2 1 
ATOM   5037  N  N   . GLY B 2 241 ? 78.924  92.680  100.542 1.00 376.34 ? 241 GLY B N   1 
ATOM   5038  C  CA  . GLY B 2 241 ? 79.819  93.827  100.684 1.00 326.04 ? 241 GLY B CA  1 
ATOM   5039  C  C   . GLY B 2 241 ? 81.290  93.478  100.953 1.00 308.28 ? 241 GLY B C   1 
ATOM   5040  O  O   . GLY B 2 241 ? 82.156  94.309  100.681 1.00 228.02 ? 241 GLY B O   1 
ATOM   5041  N  N   . ASN B 2 242 ? 81.570  92.276  101.490 1.00 355.30 ? 242 ASN B N   1 
ATOM   5042  C  CA  . ASN B 2 242 ? 82.919  91.726  101.613 1.00 329.76 ? 242 ASN B CA  1 
ATOM   5043  C  C   . ASN B 2 242 ? 83.337  91.083  100.285 1.00 291.59 ? 242 ASN B C   1 
ATOM   5044  O  O   . ASN B 2 242 ? 84.395  91.417  99.743  1.00 351.24 ? 242 ASN B O   1 
ATOM   5045  C  CB  . ASN B 2 242 ? 83.018  90.750  102.799 1.00 335.75 ? 242 ASN B CB  1 
ATOM   5046  C  CG  . ASN B 2 242 ? 83.307  91.422  104.128 1.00 349.92 ? 242 ASN B CG  1 
ATOM   5047  O  OD1 . ASN B 2 242 ? 84.400  91.262  104.667 1.00 217.50 ? 242 ASN B OD1 1 
ATOM   5048  N  ND2 . ASN B 2 242 ? 82.351  92.167  104.663 1.00 419.32 ? 242 ASN B ND2 1 
ATOM   5049  N  N   . ILE B 2 243 ? 82.502  90.169  99.767  1.00 278.10 ? 243 ILE B N   1 
ATOM   5050  C  CA  . ILE B 2 243 ? 82.755  89.458  98.516  1.00 278.94 ? 243 ILE B CA  1 
ATOM   5051  C  C   . ILE B 2 243 ? 83.078  90.429  97.372  1.00 299.58 ? 243 ILE B C   1 
ATOM   5052  O  O   . ILE B 2 243 ? 84.030  90.182  96.630  1.00 383.33 ? 243 ILE B O   1 
ATOM   5053  C  CB  . ILE B 2 243 ? 81.561  88.549  98.164  1.00 344.63 ? 243 ILE B CB  1 
ATOM   5054  C  CG1 . ILE B 2 243 ? 81.494  87.353  99.113  1.00 395.78 ? 243 ILE B CG1 1 
ATOM   5055  C  CG2 . ILE B 2 243 ? 81.586  88.084  96.708  1.00 370.11 ? 243 ILE B CG2 1 
ATOM   5056  C  CD1 . ILE B 2 243 ? 80.121  86.730  99.234  1.00 484.68 ? 243 ILE B CD1 1 
ATOM   5057  N  N   . VAL B 2 244 ? 82.310  91.517  97.211  1.00 232.92 ? 244 VAL B N   1 
ATOM   5058  C  CA  . VAL B 2 244 ? 82.569  92.451  96.120  1.00 234.07 ? 244 VAL B CA  1 
ATOM   5059  C  C   . VAL B 2 244 ? 83.960  93.098  96.226  1.00 240.12 ? 244 VAL B C   1 
ATOM   5060  O  O   . VAL B 2 244 ? 84.594  93.328  95.195  1.00 237.86 ? 244 VAL B O   1 
ATOM   5061  C  CB  . VAL B 2 244 ? 81.481  93.538  96.014  1.00 261.84 ? 244 VAL B CB  1 
ATOM   5062  C  CG1 . VAL B 2 244 ? 81.465  94.512  97.185  1.00 248.37 ? 244 VAL B CG1 1 
ATOM   5063  C  CG2 . VAL B 2 244 ? 81.615  94.309  94.711  1.00 275.82 ? 244 VAL B CG2 1 
ATOM   5064  N  N   . LEU B 2 245 ? 84.431  93.404  97.449  1.00 254.93 ? 245 LEU B N   1 
ATOM   5065  C  CA  . LEU B 2 245 ? 85.758  93.979  97.638  1.00 229.73 ? 245 LEU B CA  1 
ATOM   5066  C  C   . LEU B 2 245 ? 86.828  92.904  97.464  1.00 195.66 ? 245 LEU B C   1 
ATOM   5067  O  O   . LEU B 2 245 ? 87.945  93.257  97.101  1.00 305.85 ? 245 LEU B O   1 
ATOM   5068  C  CB  . LEU B 2 245 ? 85.860  94.642  99.018  1.00 264.19 ? 245 LEU B CB  1 
ATOM   5069  C  CG  . LEU B 2 245 ? 85.000  95.891  99.214  1.00 322.91 ? 245 LEU B CG  1 
ATOM   5070  C  CD1 . LEU B 2 245 ? 85.125  96.397  100.646 1.00 360.75 ? 245 LEU B CD1 1 
ATOM   5071  C  CD2 . LEU B 2 245 ? 85.379  96.986  98.228  1.00 260.47 ? 245 LEU B CD2 1 
ATOM   5072  N  N   . ALA B 2 246 ? 86.513  91.620  97.718  1.00 165.21 ? 246 ALA B N   1 
ATOM   5073  C  CA  . ALA B 2 246 ? 87.426  90.515  97.422  1.00 210.83 ? 246 ALA B CA  1 
ATOM   5074  C  C   . ALA B 2 246 ? 87.620  90.438  95.916  1.00 185.21 ? 246 ALA B C   1 
ATOM   5075  O  O   . ALA B 2 246 ? 88.757  90.437  95.447  1.00 271.27 ? 246 ALA B O   1 
ATOM   5076  C  CB  . ALA B 2 246 ? 86.929  89.201  97.996  1.00 267.87 ? 246 ALA B CB  1 
ATOM   5077  N  N   . LEU B 2 247 ? 86.509  90.421  95.179  1.00 163.09 ? 247 LEU B N   1 
ATOM   5078  C  CA  . LEU B 2 247 ? 86.570  90.324  93.733  1.00 184.91 ? 247 LEU B CA  1 
ATOM   5079  C  C   . LEU B 2 247 ? 87.303  91.552  93.155  1.00 196.79 ? 247 LEU B C   1 
ATOM   5080  O  O   . LEU B 2 247 ? 88.202  91.395  92.321  1.00 170.45 ? 247 LEU B O   1 
ATOM   5081  C  CB  . LEU B 2 247 ? 85.137  90.175  93.214  1.00 202.04 ? 247 LEU B CB  1 
ATOM   5082  C  CG  . LEU B 2 247 ? 85.025  89.810  91.738  1.00 269.50 ? 247 LEU B CG  1 
ATOM   5083  C  CD1 . LEU B 2 247 ? 85.257  88.326  91.555  1.00 252.57 ? 247 LEU B CD1 1 
ATOM   5084  C  CD2 . LEU B 2 247 ? 83.676  90.228  91.157  1.00 325.06 ? 247 LEU B CD2 1 
ATOM   5085  N  N   . TYR B 2 248 ? 86.951  92.771  93.609  1.00 156.40 ? 248 TYR B N   1 
ATOM   5086  C  CA  . TYR B 2 248 ? 87.548  93.997  93.078  1.00 161.84 ? 248 TYR B CA  1 
ATOM   5087  C  C   . TYR B 2 248 ? 89.062  94.071  93.424  1.00 153.37 ? 248 TYR B C   1 
ATOM   5088  O  O   . TYR B 2 248 ? 89.846  94.644  92.671  1.00 165.66 ? 248 TYR B O   1 
ATOM   5089  C  CB  . TYR B 2 248 ? 86.728  95.252  93.490  1.00 224.03 ? 248 TYR B CB  1 
ATOM   5090  C  CG  . TYR B 2 248 ? 87.363  96.430  92.765  1.00 215.71 ? 248 TYR B CG  1 
ATOM   5091  C  CD1 . TYR B 2 248 ? 87.126  96.597  91.411  1.00 220.71 ? 248 TYR B CD1 1 
ATOM   5092  C  CD2 . TYR B 2 248 ? 88.236  97.319  93.402  1.00 209.01 ? 248 TYR B CD2 1 
ATOM   5093  C  CE1 . TYR B 2 248 ? 87.722  97.624  90.706  1.00 320.77 ? 248 TYR B CE1 1 
ATOM   5094  C  CE2 . TYR B 2 248 ? 88.836  98.354  92.708  1.00 229.63 ? 248 TYR B CE2 1 
ATOM   5095  C  CZ  . TYR B 2 248 ? 88.578  98.499  91.353  1.00 332.08 ? 248 TYR B CZ  1 
ATOM   5096  O  OH  . TYR B 2 248 ? 89.130  99.478  90.580  1.00 425.20 ? 248 TYR B OH  1 
ATOM   5097  N  N   . SER B 2 249 ? 89.505  93.507  94.553  1.00 164.64 ? 249 SER B N   1 
ATOM   5098  C  CA  . SER B 2 249 ? 90.920  93.471  94.915  1.00 183.22 ? 249 SER B CA  1 
ATOM   5099  C  C   . SER B 2 249 ? 91.673  92.347  94.193  1.00 152.80 ? 249 SER B C   1 
ATOM   5100  O  O   . SER B 2 249 ? 92.902  92.339  94.181  1.00 196.02 ? 249 SER B O   1 
ATOM   5101  C  CB  . SER B 2 249 ? 91.104  93.312  96.410  1.00 279.46 ? 249 SER B CB  1 
ATOM   5102  O  OG  . SER B 2 249 ? 90.415  94.325  97.133  1.00 316.50 ? 249 SER B OG  1 
ATOM   5103  N  N   . GLY B 2 250 ? 90.955  91.389  93.603  1.00 174.05 ? 250 GLY B N   1 
ATOM   5104  C  CA  . GLY B 2 250 ? 91.556  90.309  92.838  1.00 162.76 ? 250 GLY B CA  1 
ATOM   5105  C  C   . GLY B 2 250 ? 91.746  90.706  91.380  1.00 149.91 ? 250 GLY B C   1 
ATOM   5106  O  O   . GLY B 2 250 ? 92.747  90.329  90.811  1.00 144.78 ? 250 GLY B O   1 
ATOM   5107  N  N   . LEU B 2 251 ? 90.790  91.441  90.791  1.00 156.29 ? 251 LEU B N   1 
ATOM   5108  C  CA  . LEU B 2 251 ? 90.837  91.867  89.393  1.00 179.24 ? 251 LEU B CA  1 
ATOM   5109  C  C   . LEU B 2 251 ? 92.122  92.611  89.010  1.00 168.82 ? 251 LEU B C   1 
ATOM   5110  O  O   . LEU B 2 251 ? 92.575  92.514  87.879  1.00 146.13 ? 251 LEU B O   1 
ATOM   5111  C  CB  . LEU B 2 251 ? 89.633  92.777  89.126  1.00 215.70 ? 251 LEU B CB  1 
ATOM   5112  C  CG  . LEU B 2 251 ? 88.348  92.052  88.764  1.00 243.46 ? 251 LEU B CG  1 
ATOM   5113  C  CD1 . LEU B 2 251 ? 87.160  92.980  88.893  1.00 286.77 ? 251 LEU B CD1 1 
ATOM   5114  C  CD2 . LEU B 2 251 ? 88.423  91.532  87.347  1.00 301.84 ? 251 LEU B CD2 1 
ATOM   5115  N  N   . PHE B 2 252 ? 92.708  93.366  89.941  1.00 161.99 ? 252 PHE B N   1 
ATOM   5116  C  CA  . PHE B 2 252 ? 94.016  93.969  89.753  1.00 162.08 ? 252 PHE B CA  1 
ATOM   5117  C  C   . PHE B 2 252 ? 95.060  92.961  89.244  1.00 144.35 ? 252 PHE B C   1 
ATOM   5118  O  O   . PHE B 2 252 ? 95.873  93.318  88.398  1.00 168.05 ? 252 PHE B O   1 
ATOM   5119  C  CB  . PHE B 2 252 ? 94.494  94.579  91.073  1.00 214.55 ? 252 PHE B CB  1 
ATOM   5120  C  CG  . PHE B 2 252 ? 95.924  95.049  91.017  1.00 196.81 ? 252 PHE B CG  1 
ATOM   5121  C  CD1 . PHE B 2 252 ? 96.193  96.309  90.557  1.00 227.95 ? 252 PHE B CD1 1 
ATOM   5122  C  CD2 . PHE B 2 252 ? 96.991  94.234  91.388  1.00 207.16 ? 252 PHE B CD2 1 
ATOM   5123  C  CE1 . PHE B 2 252 ? 97.500  96.771  90.501  1.00 271.63 ? 252 PHE B CE1 1 
ATOM   5124  C  CE2 . PHE B 2 252 ? 98.298  94.677  91.310  1.00 166.58 ? 252 PHE B CE2 1 
ATOM   5125  C  CZ  . PHE B 2 252 ? 98.547  95.952  90.877  1.00 240.53 ? 252 PHE B CZ  1 
ATOM   5126  N  N   . ALA B 2 253 ? 95.064  91.712  89.732  1.00 120.05 ? 253 ALA B N   1 
ATOM   5127  C  CA  . ALA B 2 253 ? 96.085  90.749  89.339  1.00 152.23 ? 253 ALA B CA  1 
ATOM   5128  C  C   . ALA B 2 253 ? 95.907  90.256  87.897  1.00 124.80 ? 253 ALA B C   1 
ATOM   5129  O  O   . ALA B 2 253 ? 96.859  89.737  87.324  1.00 136.09 ? 253 ALA B O   1 
ATOM   5130  C  CB  . ALA B 2 253 ? 96.103  89.600  90.309  1.00 202.99 ? 253 ALA B CB  1 
ATOM   5131  N  N   . TYR B 2 254 ? 94.729  90.438  87.308  1.00 120.50 ? 254 TYR B N   1 
ATOM   5132  C  CA  . TYR B 2 254 ? 94.522  90.180  85.890  1.00 164.39 ? 254 TYR B CA  1 
ATOM   5133  C  C   . TYR B 2 254 ? 94.691  91.403  84.972  1.00 158.87 ? 254 TYR B C   1 
ATOM   5134  O  O   . TYR B 2 254 ? 94.791  91.255  83.741  1.00 126.79 ? 254 TYR B O   1 
ATOM   5135  C  CB  . TYR B 2 254 ? 93.102  89.649  85.784  1.00 154.09 ? 254 TYR B CB  1 
ATOM   5136  C  CG  . TYR B 2 254 ? 92.953  88.214  86.238  1.00 150.69 ? 254 TYR B CG  1 
ATOM   5137  C  CD1 . TYR B 2 254 ? 93.304  87.155  85.413  1.00 172.72 ? 254 TYR B CD1 1 
ATOM   5138  C  CD2 . TYR B 2 254 ? 92.416  87.927  87.465  1.00 187.09 ? 254 TYR B CD2 1 
ATOM   5139  C  CE1 . TYR B 2 254 ? 93.138  85.845  85.805  1.00 166.11 ? 254 TYR B CE1 1 
ATOM   5140  C  CE2 . TYR B 2 254 ? 92.229  86.616  87.865  1.00 230.79 ? 254 TYR B CE2 1 
ATOM   5141  C  CZ  . TYR B 2 254 ? 92.597  85.570  87.041  1.00 197.10 ? 254 TYR B CZ  1 
ATOM   5142  O  OH  . TYR B 2 254 ? 92.411  84.281  87.446  1.00 269.31 ? 254 TYR B OH  1 
ATOM   5143  N  N   . GLY B 2 255 ? 94.704  92.596  85.571  1.00 142.83 ? 255 GLY B N   1 
ATOM   5144  C  CA  . GLY B 2 255 ? 94.836  93.841  84.839  1.00 179.21 ? 255 GLY B CA  1 
ATOM   5145  C  C   . GLY B 2 255 ? 96.084  93.872  83.969  1.00 146.07 ? 255 GLY B C   1 
ATOM   5146  O  O   . GLY B 2 255 ? 97.190  93.627  84.467  1.00 145.57 ? 255 GLY B O   1 
ATOM   5147  N  N   . GLY B 2 256 ? 95.856  94.167  82.682  1.00 120.83 ? 256 GLY B N   1 
ATOM   5148  C  CA  . GLY B 2 256 ? 96.891  94.008  81.677  1.00 151.54 ? 256 GLY B CA  1 
ATOM   5149  C  C   . GLY B 2 256 ? 96.418  93.325  80.400  1.00 136.79 ? 256 GLY B C   1 
ATOM   5150  O  O   . GLY B 2 256 ? 97.054  93.520  79.376  1.00 175.61 ? 256 GLY B O   1 
ATOM   5151  N  N   . TRP B 2 257 ? 95.334  92.539  80.460  1.00 133.28 ? 257 TRP B N   1 
ATOM   5152  C  CA  . TRP B 2 257 ? 94.869  91.746  79.320  1.00 131.37 ? 257 TRP B CA  1 
ATOM   5153  C  C   . TRP B 2 257 ? 94.590  92.588  78.074  1.00 132.66 ? 257 TRP B C   1 
ATOM   5154  O  O   . TRP B 2 257 ? 94.565  92.017  76.978  1.00 122.22 ? 257 TRP B O   1 
ATOM   5155  C  CB  . TRP B 2 257 ? 93.628  90.873  79.628  1.00 120.63 ? 257 TRP B CB  1 
ATOM   5156  C  CG  . TRP B 2 257 ? 92.472  91.589  80.256  1.00 139.41 ? 257 TRP B CG  1 
ATOM   5157  C  CD1 . TRP B 2 257 ? 92.160  91.718  81.591  1.00 222.66 ? 257 TRP B CD1 1 
ATOM   5158  C  CD2 . TRP B 2 257 ? 91.471  92.322  79.546  1.00 108.84 ? 257 TRP B CD2 1 
ATOM   5159  N  NE1 . TRP B 2 257 ? 91.032  92.480  81.767  1.00 162.65 ? 257 TRP B NE1 1 
ATOM   5160  C  CE2 . TRP B 2 257 ? 90.595  92.869  80.526  1.00 187.66 ? 257 TRP B CE2 1 
ATOM   5161  C  CE3 . TRP B 2 257 ? 91.232  92.586  78.201  1.00 122.49 ? 257 TRP B CE3 1 
ATOM   5162  C  CZ2 . TRP B 2 257 ? 89.494  93.656  80.177  1.00 255.84 ? 257 TRP B CZ2 1 
ATOM   5163  C  CZ3 . TRP B 2 257 ? 90.143  93.371  77.865  1.00 198.98 ? 257 TRP B CZ3 1 
ATOM   5164  C  CH2 . TRP B 2 257 ? 89.290  93.907  78.835  1.00 234.09 ? 257 TRP B CH2 1 
ATOM   5165  N  N   . ASN B 2 258 ? 94.389  93.908  78.212  1.00 116.79 ? 258 ASN B N   1 
ATOM   5166  C  CA  . ASN B 2 258 ? 94.113  94.726  77.037  1.00 150.29 ? 258 ASN B CA  1 
ATOM   5167  C  C   . ASN B 2 258 ? 95.381  95.176  76.289  1.00 150.93 ? 258 ASN B C   1 
ATOM   5168  O  O   . ASN B 2 258 ? 95.273  95.745  75.198  1.00 183.32 ? 258 ASN B O   1 
ATOM   5169  C  CB  . ASN B 2 258 ? 93.180  95.882  77.395  1.00 135.75 ? 258 ASN B CB  1 
ATOM   5170  C  CG  . ASN B 2 258 ? 93.758  96.788  78.437  1.00 165.93 ? 258 ASN B CG  1 
ATOM   5171  O  OD1 . ASN B 2 258 ? 94.771  97.423  78.154  1.00 213.89 ? 258 ASN B OD1 1 
ATOM   5172  N  ND2 . ASN B 2 258 ? 93.120  96.871  79.604  1.00 230.57 ? 258 ASN B ND2 1 
ATOM   5173  N  N   . TYR B 2 259 ? 96.573  94.915  76.815  1.00 122.87 ? 259 TYR B N   1 
ATOM   5174  C  CA  . TYR B 2 259 ? 97.777  95.556  76.314  1.00 166.77 ? 259 TYR B CA  1 
ATOM   5175  C  C   . TYR B 2 259 ? 98.171  95.146  74.893  1.00 181.34 ? 259 TYR B C   1 
ATOM   5176  O  O   . TYR B 2 259 ? 98.828  95.942  74.196  1.00 160.02 ? 259 TYR B O   1 
ATOM   5177  C  CB  . TYR B 2 259 ? 98.991  95.280  77.202  1.00 203.72 ? 259 TYR B CB  1 
ATOM   5178  C  CG  . TYR B 2 259 ? 99.200  96.290  78.326  1.00 198.95 ? 259 TYR B CG  1 
ATOM   5179  C  CD1 . TYR B 2 259 ? 98.133  96.774  79.083  1.00 200.84 ? 259 TYR B CD1 1 
ATOM   5180  C  CD2 . TYR B 2 259 ? 100.478 96.758  78.626  1.00 162.38 ? 259 TYR B CD2 1 
ATOM   5181  C  CE1 . TYR B 2 259 ? 98.336  97.699  80.095  1.00 203.02 ? 259 TYR B CE1 1 
ATOM   5182  C  CE2 . TYR B 2 259 ? 100.684 97.672  79.637  1.00 196.00 ? 259 TYR B CE2 1 
ATOM   5183  C  CZ  . TYR B 2 259 ? 99.613  98.139  80.376  1.00 243.77 ? 259 TYR B CZ  1 
ATOM   5184  O  OH  . TYR B 2 259 ? 99.796  99.023  81.398  1.00 360.81 ? 259 TYR B OH  1 
ATOM   5185  N  N   . LEU B 2 260 ? 97.763  93.943  74.460  1.00 187.72 ? 260 LEU B N   1 
ATOM   5186  C  CA  . LEU B 2 260 ? 98.063  93.506  73.102  1.00 179.80 ? 260 LEU B CA  1 
ATOM   5187  C  C   . LEU B 2 260 ? 97.495  94.451  72.036  1.00 128.30 ? 260 LEU B C   1 
ATOM   5188  O  O   . LEU B 2 260 ? 98.115  94.702  71.007  1.00 90.27  ? 260 LEU B O   1 
ATOM   5189  C  CB  . LEU B 2 260 ? 97.539  92.093  72.861  1.00 149.78 ? 260 LEU B CB  1 
ATOM   5190  C  CG  . LEU B 2 260 ? 98.188  91.441  71.631  1.00 192.82 ? 260 LEU B CG  1 
ATOM   5191  C  CD1 . LEU B 2 260 ? 99.727  91.308  71.679  1.00 120.48 ? 260 LEU B CD1 1 
ATOM   5192  C  CD2 . LEU B 2 260 ? 97.628  90.074  71.415  1.00 236.15 ? 260 LEU B CD2 1 
ATOM   5193  N  N   . ASN B 2 261 ? 96.316  94.993  72.299  1.00 138.56 ? 261 ASN B N   1 
ATOM   5194  C  CA  . ASN B 2 261 ? 95.628  95.876  71.370  1.00 141.95 ? 261 ASN B CA  1 
ATOM   5195  C  C   . ASN B 2 261 ? 96.454  97.103  70.973  1.00 134.07 ? 261 ASN B C   1 
ATOM   5196  O  O   . ASN B 2 261 ? 96.361  97.512  69.815  1.00 186.64 ? 261 ASN B O   1 
ATOM   5197  C  CB  . ASN B 2 261 ? 94.247  96.211  71.917  1.00 131.95 ? 261 ASN B CB  1 
ATOM   5198  C  CG  . ASN B 2 261 ? 93.387  94.959  71.885  1.00 193.79 ? 261 ASN B CG  1 
ATOM   5199  O  OD1 . ASN B 2 261 ? 93.605  94.019  72.655  1.00 209.73 ? 261 ASN B OD1 1 
ATOM   5200  N  ND2 . ASN B 2 261 ? 92.405  94.928  70.988  1.00 218.56 ? 261 ASN B ND2 1 
ATOM   5201  N  N   . PHE B 2 262 ? 97.278  97.655  71.862  1.00 109.22 ? 262 PHE B N   1 
ATOM   5202  C  CA  . PHE B 2 262 ? 98.117  98.778  71.479  1.00 116.25 ? 262 PHE B CA  1 
ATOM   5203  C  C   . PHE B 2 262 ? 99.273  98.387  70.539  1.00 113.81 ? 262 PHE B C   1 
ATOM   5204  O  O   . PHE B 2 262 ? 100.065 99.282  70.160  1.00 143.63 ? 262 PHE B O   1 
ATOM   5205  C  CB  . PHE B 2 262 ? 98.747  99.479  72.693  1.00 153.53 ? 262 PHE B CB  1 
ATOM   5206  C  CG  . PHE B 2 262 ? 97.847  99.933  73.803  1.00 148.62 ? 262 PHE B CG  1 
ATOM   5207  C  CD1 . PHE B 2 262 ? 97.162  101.125 73.693  1.00 179.25 ? 262 PHE B CD1 1 
ATOM   5208  C  CD2 . PHE B 2 262 ? 97.697  99.177  74.958  1.00 177.39 ? 262 PHE B CD2 1 
ATOM   5209  C  CE1 . PHE B 2 262 ? 96.320  101.544 74.717  1.00 258.20 ? 262 PHE B CE1 1 
ATOM   5210  C  CE2 . PHE B 2 262 ? 96.861  99.594  75.984  1.00 252.47 ? 262 PHE B CE2 1 
ATOM   5211  C  CZ  . PHE B 2 262 ? 96.172  100.781 75.860  1.00 291.44 ? 262 PHE B CZ  1 
ATOM   5212  N  N   . VAL B 2 263 ? 99.425  97.104  70.167  1.00 103.07 ? 263 VAL B N   1 
ATOM   5213  C  CA  . VAL B 2 263 ? 100.425 96.732  69.170  1.00 136.13 ? 263 VAL B CA  1 
ATOM   5214  C  C   . VAL B 2 263 ? 99.818  95.925  68.029  1.00 176.83 ? 263 VAL B C   1 
ATOM   5215  O  O   . VAL B 2 263 ? 100.551 95.215  67.350  1.00 174.66 ? 263 VAL B O   1 
ATOM   5216  C  CB  . VAL B 2 263 ? 101.592 95.982  69.837  1.00 134.96 ? 263 VAL B CB  1 
ATOM   5217  C  CG1 . VAL B 2 263 ? 102.234 96.876  70.905  1.00 173.94 ? 263 VAL B CG1 1 
ATOM   5218  C  CG2 . VAL B 2 263 ? 101.205 94.608  70.392  1.00 127.71 ? 263 VAL B CG2 1 
ATOM   5219  N  N   . THR B 2 264 ? 98.498  96.062  67.802  1.00 205.28 ? 264 THR B N   1 
ATOM   5220  C  CA  . THR B 2 264 ? 97.775  95.368  66.741  1.00 175.66 ? 264 THR B CA  1 
ATOM   5221  C  C   . THR B 2 264 ? 98.464  95.553  65.394  1.00 200.16 ? 264 THR B C   1 
ATOM   5222  O  O   . THR B 2 264 ? 98.545  94.613  64.593  1.00 178.73 ? 264 THR B O   1 
ATOM   5223  C  CB  . THR B 2 264 ? 96.345  95.905  66.617  1.00 161.34 ? 264 THR B CB  1 
ATOM   5224  O  OG1 . THR B 2 264 ? 95.655  95.755  67.857  1.00 187.37 ? 264 THR B OG1 1 
ATOM   5225  C  CG2 . THR B 2 264 ? 95.558  95.178  65.554  1.00 232.94 ? 264 THR B CG2 1 
ATOM   5226  N  N   . GLU B 2 265 ? 98.949  96.780  65.164  1.00 187.31 ? 265 GLU B N   1 
ATOM   5227  C  CA  . GLU B 2 265 ? 99.448  97.205  63.863  1.00 208.20 ? 265 GLU B CA  1 
ATOM   5228  C  C   . GLU B 2 265 ? 100.805 96.588  63.522  1.00 196.47 ? 265 GLU B C   1 
ATOM   5229  O  O   . GLU B 2 265 ? 101.184 96.613  62.343  1.00 262.24 ? 265 GLU B O   1 
ATOM   5230  C  CB  . GLU B 2 265 ? 99.495  98.723  63.837  1.00 204.94 ? 265 GLU B CB  1 
ATOM   5231  C  CG  . GLU B 2 265 ? 99.388  99.424  62.490  1.00 294.27 ? 265 GLU B CG  1 
ATOM   5232  C  CD  . GLU B 2 265 ? 99.090  100.917 62.629  1.00 371.46 ? 265 GLU B CD  1 
ATOM   5233  O  OE1 . GLU B 2 265 ? 98.601  101.323 63.703  1.00 435.55 ? 265 GLU B OE1 1 
ATOM   5234  O  OE2 . GLU B 2 265 ? 99.348  101.691 61.680  1.00 443.21 ? 265 GLU B OE2 1 
ATOM   5235  N  N   . GLU B 2 266 ? 101.521 96.030  64.521  1.00 157.97 ? 266 GLU B N   1 
ATOM   5236  C  CA  . GLU B 2 266 ? 102.800 95.345  64.321  1.00 200.83 ? 266 GLU B CA  1 
ATOM   5237  C  C   . GLU B 2 266 ? 102.706 93.813  64.384  1.00 187.21 ? 266 GLU B C   1 
ATOM   5238  O  O   . GLU B 2 266 ? 103.743 93.161  64.397  1.00 171.37 ? 266 GLU B O   1 
ATOM   5239  C  CB  . GLU B 2 266 ? 103.793 95.897  65.346  1.00 213.48 ? 266 GLU B CB  1 
ATOM   5240  C  CG  . GLU B 2 266 ? 104.145 97.346  65.065  1.00 282.26 ? 266 GLU B CG  1 
ATOM   5241  C  CD  . GLU B 2 266 ? 104.907 98.068  66.151  1.00 288.58 ? 266 GLU B CD  1 
ATOM   5242  O  OE1 . GLU B 2 266 ? 106.122 97.799  66.318  1.00 241.15 ? 266 GLU B OE1 1 
ATOM   5243  O  OE2 . GLU B 2 266 ? 104.273 98.897  66.834  1.00 291.63 ? 266 GLU B OE2 1 
ATOM   5244  N  N   . MET B 2 267 ? 101.499 93.237  64.392  1.00 171.27 ? 267 MET B N   1 
ATOM   5245  C  CA  . MET B 2 267 ? 101.310 91.796  64.323  1.00 218.30 ? 267 MET B CA  1 
ATOM   5246  C  C   . MET B 2 267 ? 101.549 91.293  62.894  1.00 239.61 ? 267 MET B C   1 
ATOM   5247  O  O   . MET B 2 267 ? 101.146 91.968  61.940  1.00 194.02 ? 267 MET B O   1 
ATOM   5248  C  CB  . MET B 2 267 ? 99.867  91.456  64.707  1.00 248.69 ? 267 MET B CB  1 
ATOM   5249  C  CG  . MET B 2 267 ? 99.478  91.786  66.131  1.00 186.85 ? 267 MET B CG  1 
ATOM   5250  S  SD  . MET B 2 267 ? 100.354 90.732  67.260  1.00 225.99 ? 267 MET B SD  1 
ATOM   5251  C  CE  . MET B 2 267 ? 99.104  89.503  67.614  1.00 220.44 ? 267 MET B CE  1 
ATOM   5252  N  N   . ILE B 2 268 ? 102.180 90.107  62.735  1.00 246.66 ? 268 ILE B N   1 
ATOM   5253  C  CA  . ILE B 2 268 ? 102.440 89.541  61.411  1.00 216.12 ? 268 ILE B CA  1 
ATOM   5254  C  C   . ILE B 2 268 ? 101.130 89.274  60.662  1.00 234.46 ? 268 ILE B C   1 
ATOM   5255  O  O   . ILE B 2 268 ? 101.099 89.372  59.435  1.00 287.73 ? 268 ILE B O   1 
ATOM   5256  C  CB  . ILE B 2 268 ? 103.303 88.255  61.448  1.00 245.71 ? 268 ILE B CB  1 
ATOM   5257  C  CG1 . ILE B 2 268 ? 102.696 87.125  62.297  1.00 321.78 ? 268 ILE B CG1 1 
ATOM   5258  C  CG2 . ILE B 2 268 ? 104.724 88.582  61.869  1.00 230.47 ? 268 ILE B CG2 1 
ATOM   5259  C  CD1 . ILE B 2 268 ? 103.426 85.790  62.200  1.00 363.56 ? 268 ILE B CD1 1 
ATOM   5260  N  N   . ASN B 2 269 ? 100.057 88.924  61.394  1.00 194.50 ? 269 ASN B N   1 
ATOM   5261  C  CA  . ASN B 2 269 ? 98.781  88.546  60.803  1.00 214.64 ? 269 ASN B CA  1 
ATOM   5262  C  C   . ASN B 2 269 ? 97.669  88.859  61.802  1.00 157.37 ? 269 ASN B C   1 
ATOM   5263  O  O   . ASN B 2 269 ? 97.174  87.950  62.466  1.00 146.37 ? 269 ASN B O   1 
ATOM   5264  C  CB  . ASN B 2 269 ? 98.806  87.073  60.373  1.00 240.22 ? 269 ASN B CB  1 
ATOM   5265  C  CG  . ASN B 2 269 ? 97.566  86.630  59.619  1.00 301.18 ? 269 ASN B CG  1 
ATOM   5266  O  OD1 . ASN B 2 269 ? 96.642  87.411  59.376  1.00 288.18 ? 269 ASN B OD1 1 
ATOM   5267  N  ND2 . ASN B 2 269 ? 97.537  85.363  59.237  1.00 351.97 ? 269 ASN B ND2 1 
ATOM   5268  N  N   . PRO B 2 270 ? 97.267  90.142  61.965  1.00 175.58 ? 270 PRO B N   1 
ATOM   5269  C  CA  . PRO B 2 270 ? 96.433  90.539  63.099  1.00 217.34 ? 270 PRO B CA  1 
ATOM   5270  C  C   . PRO B 2 270 ? 95.086  89.826  63.141  1.00 206.64 ? 270 PRO B C   1 
ATOM   5271  O  O   . PRO B 2 270 ? 94.685  89.398  64.214  1.00 300.09 ? 270 PRO B O   1 
ATOM   5272  C  CB  . PRO B 2 270 ? 96.269  92.068  62.983  1.00 264.29 ? 270 PRO B CB  1 
ATOM   5273  C  CG  . PRO B 2 270 ? 96.669  92.391  61.573  1.00 261.26 ? 270 PRO B CG  1 
ATOM   5274  C  CD  . PRO B 2 270 ? 97.609  91.293  61.114  1.00 217.35 ? 270 PRO B CD  1 
ATOM   5275  N  N   . TYR B 2 271 ? 94.411  89.676  61.996  1.00 189.44 ? 271 TYR B N   1 
ATOM   5276  C  CA  . TYR B 2 271 ? 93.050  89.157  61.985  1.00 209.24 ? 271 TYR B CA  1 
ATOM   5277  C  C   . TYR B 2 271 ? 92.983  87.716  62.515  1.00 222.44 ? 271 TYR B C   1 
ATOM   5278  O  O   . TYR B 2 271 ? 91.975  87.359  63.123  1.00 207.67 ? 271 TYR B O   1 
ATOM   5279  C  CB  . TYR B 2 271 ? 92.478  89.277  60.576  1.00 264.59 ? 271 TYR B CB  1 
ATOM   5280  C  CG  . TYR B 2 271 ? 92.574  90.684  60.006  1.00 312.20 ? 271 TYR B CG  1 
ATOM   5281  C  CD1 . TYR B 2 271 ? 91.730  91.709  60.429  1.00 327.46 ? 271 TYR B CD1 1 
ATOM   5282  C  CD2 . TYR B 2 271 ? 93.534  90.986  59.046  1.00 391.21 ? 271 TYR B CD2 1 
ATOM   5283  C  CE1 . TYR B 2 271 ? 91.838  92.990  59.902  1.00 369.85 ? 271 TYR B CE1 1 
ATOM   5284  C  CE2 . TYR B 2 271 ? 93.649  92.262  58.513  1.00 432.74 ? 271 TYR B CE2 1 
ATOM   5285  C  CZ  . TYR B 2 271 ? 92.798  93.268  58.942  1.00 417.35 ? 271 TYR B CZ  1 
ATOM   5286  O  OH  . TYR B 2 271 ? 92.924  94.517  58.400  1.00 431.63 ? 271 TYR B OH  1 
ATOM   5287  N  N   . ARG B 2 272 ? 94.031  86.893  62.309  1.00 194.00 ? 272 ARG B N   1 
ATOM   5288  C  CA  . ARG B 2 272 ? 94.153  85.611  62.999  1.00 206.29 ? 272 ARG B CA  1 
ATOM   5289  C  C   . ARG B 2 272 ? 94.767  85.758  64.396  1.00 233.62 ? 272 ARG B C   1 
ATOM   5290  O  O   . ARG B 2 272 ? 94.171  85.283  65.366  1.00 220.15 ? 272 ARG B O   1 
ATOM   5291  C  CB  . ARG B 2 272 ? 95.010  84.612  62.220  1.00 236.29 ? 272 ARG B CB  1 
ATOM   5292  C  CG  . ARG B 2 272 ? 95.139  83.250  62.895  1.00 260.26 ? 272 ARG B CG  1 
ATOM   5293  C  CD  . ARG B 2 272 ? 96.010  82.252  62.149  1.00 231.96 ? 272 ARG B CD  1 
ATOM   5294  N  NE  . ARG B 2 272 ? 96.330  81.082  62.973  1.00 223.87 ? 272 ARG B NE  1 
ATOM   5295  C  CZ  . ARG B 2 272 ? 97.551  80.560  63.199  1.00 274.83 ? 272 ARG B CZ  1 
ATOM   5296  N  NH1 . ARG B 2 272 ? 97.691  79.533  64.028  1.00 219.10 ? 272 ARG B NH1 1 
ATOM   5297  N  NH2 . ARG B 2 272 ? 98.641  81.040  62.612  1.00 292.65 ? 272 ARG B NH2 1 
ATOM   5298  N  N   . ASN B 2 273 ? 95.956  86.376  64.501  1.00 244.89 ? 273 ASN B N   1 
ATOM   5299  C  CA  . ASN B 2 273 ? 96.797  86.237  65.690  1.00 225.52 ? 273 ASN B CA  1 
ATOM   5300  C  C   . ASN B 2 273 ? 96.312  87.106  66.858  1.00 166.67 ? 273 ASN B C   1 
ATOM   5301  O  O   . ASN B 2 273 ? 96.544  86.729  67.984  1.00 127.60 ? 273 ASN B O   1 
ATOM   5302  C  CB  . ASN B 2 273 ? 98.274  86.532  65.389  1.00 245.31 ? 273 ASN B CB  1 
ATOM   5303  C  CG  . ASN B 2 273 ? 98.946  85.579  64.419  1.00 247.91 ? 273 ASN B CG  1 
ATOM   5304  O  OD1 . ASN B 2 273 ? 99.882  85.992  63.743  1.00 282.01 ? 273 ASN B OD1 1 
ATOM   5305  N  ND2 . ASN B 2 273 ? 98.504  84.334  64.308  1.00 262.52 ? 273 ASN B ND2 1 
ATOM   5306  N  N   . LEU B 2 274 ? 95.655  88.254  66.644  1.00 162.89 ? 274 LEU B N   1 
ATOM   5307  C  CA  . LEU B 2 274 ? 95.208  89.084  67.764  1.00 169.04 ? 274 LEU B CA  1 
ATOM   5308  C  C   . LEU B 2 274 ? 94.146  88.398  68.631  1.00 176.44 ? 274 LEU B C   1 
ATOM   5309  O  O   . LEU B 2 274 ? 94.330  88.387  69.832  1.00 192.77 ? 274 LEU B O   1 
ATOM   5310  C  CB  . LEU B 2 274 ? 94.686  90.427  67.265  1.00 199.64 ? 274 LEU B CB  1 
ATOM   5311  C  CG  . LEU B 2 274 ? 94.543  91.485  68.355  1.00 191.41 ? 274 LEU B CG  1 
ATOM   5312  C  CD1 . LEU B 2 274 ? 95.884  92.160  68.617  1.00 169.45 ? 274 LEU B CD1 1 
ATOM   5313  C  CD2 . LEU B 2 274 ? 93.484  92.501  67.967  1.00 268.44 ? 274 LEU B CD2 1 
ATOM   5314  N  N   . PRO B 2 275 ? 93.032  87.807  68.134  1.00 166.63 ? 275 PRO B N   1 
ATOM   5315  C  CA  . PRO B 2 275 ? 92.170  86.995  68.986  1.00 192.40 ? 275 PRO B CA  1 
ATOM   5316  C  C   . PRO B 2 275 ? 92.838  85.701  69.470  1.00 191.81 ? 275 PRO B C   1 
ATOM   5317  O  O   . PRO B 2 275 ? 92.601  85.310  70.606  1.00 188.42 ? 275 PRO B O   1 
ATOM   5318  C  CB  . PRO B 2 275 ? 90.948  86.722  68.107  1.00 219.45 ? 275 PRO B CB  1 
ATOM   5319  C  CG  . PRO B 2 275 ? 91.508  86.731  66.729  1.00 249.82 ? 275 PRO B CG  1 
ATOM   5320  C  CD  . PRO B 2 275 ? 92.528  87.845  66.766  1.00 202.51 ? 275 PRO B CD  1 
ATOM   5321  N  N   . LEU B 2 276 ? 93.678  85.046  68.661  1.00 140.17 ? 276 LEU B N   1 
ATOM   5322  C  CA  . LEU B 2 276 ? 94.321  83.833  69.142  1.00 191.29 ? 276 LEU B CA  1 
ATOM   5323  C  C   . LEU B 2 276 ? 95.285  84.111  70.305  1.00 233.32 ? 276 LEU B C   1 
ATOM   5324  O  O   . LEU B 2 276 ? 95.329  83.329  71.238  1.00 205.16 ? 276 LEU B O   1 
ATOM   5325  C  CB  . LEU B 2 276 ? 95.040  83.126  67.995  1.00 206.94 ? 276 LEU B CB  1 
ATOM   5326  C  CG  . LEU B 2 276 ? 95.583  81.735  68.340  1.00 271.31 ? 276 LEU B CG  1 
ATOM   5327  C  CD1 . LEU B 2 276 ? 94.495  80.792  68.850  1.00 331.66 ? 276 LEU B CD1 1 
ATOM   5328  C  CD2 . LEU B 2 276 ? 96.273  81.109  67.131  1.00 352.50 ? 276 LEU B CD2 1 
ATOM   5329  N  N   . ALA B 2 277 ? 96.058  85.201  70.290  1.00 262.21 ? 277 ALA B N   1 
ATOM   5330  C  CA  . ALA B 2 277 ? 97.002  85.502  71.370  1.00 217.36 ? 277 ALA B CA  1 
ATOM   5331  C  C   . ALA B 2 277 ? 96.295  85.801  72.683  1.00 170.26 ? 277 ALA B C   1 
ATOM   5332  O  O   . ALA B 2 277 ? 96.869  85.568  73.749  1.00 222.60 ? 277 ALA B O   1 
ATOM   5333  C  CB  . ALA B 2 277 ? 97.882  86.663  70.995  1.00 222.06 ? 277 ALA B CB  1 
ATOM   5334  N  N   . ILE B 2 278 ? 95.047  86.303  72.612  1.00 122.43 ? 278 ILE B N   1 
ATOM   5335  C  CA  . ILE B 2 278 ? 94.218  86.418  73.808  1.00 144.02 ? 278 ILE B CA  1 
ATOM   5336  C  C   . ILE B 2 278 ? 93.826  85.028  74.328  1.00 145.77 ? 278 ILE B C   1 
ATOM   5337  O  O   . ILE B 2 278 ? 94.063  84.718  75.502  1.00 114.59 ? 278 ILE B O   1 
ATOM   5338  C  CB  . ILE B 2 278 ? 93.054  87.397  73.540  1.00 131.64 ? 278 ILE B CB  1 
ATOM   5339  C  CG1 . ILE B 2 278 ? 93.655  88.809  73.611  1.00 127.86 ? 278 ILE B CG1 1 
ATOM   5340  C  CG2 . ILE B 2 278 ? 91.817  87.167  74.439  1.00 121.17 ? 278 ILE B CG2 1 
ATOM   5341  C  CD1 . ILE B 2 278 ? 92.720  89.924  73.194  1.00 188.02 ? 278 ILE B CD1 1 
ATOM   5342  N  N   . ILE B 2 279 ? 93.249  84.180  73.477  1.00 144.50 ? 279 ILE B N   1 
ATOM   5343  C  CA  . ILE B 2 279 ? 92.718  82.902  73.936  1.00 168.60 ? 279 ILE B CA  1 
ATOM   5344  C  C   . ILE B 2 279 ? 93.841  81.920  74.299  1.00 154.73 ? 279 ILE B C   1 
ATOM   5345  O  O   . ILE B 2 279 ? 93.610  81.024  75.124  1.00 129.57 ? 279 ILE B O   1 
ATOM   5346  C  CB  . ILE B 2 279 ? 91.698  82.393  72.889  1.00 238.41 ? 279 ILE B CB  1 
ATOM   5347  C  CG1 . ILE B 2 279 ? 90.500  83.341  72.878  1.00 255.57 ? 279 ILE B CG1 1 
ATOM   5348  C  CG2 . ILE B 2 279 ? 91.276  80.937  73.100  1.00 297.11 ? 279 ILE B CG2 1 
ATOM   5349  C  CD1 . ILE B 2 279 ? 89.861  83.535  74.251  1.00 248.47 ? 279 ILE B CD1 1 
ATOM   5350  N  N   . ILE B 2 280 ? 95.038  82.072  73.705  1.00 143.84 ? 280 ILE B N   1 
ATOM   5351  C  CA  . ILE B 2 280 ? 96.195  81.283  74.094  1.00 188.80 ? 280 ILE B CA  1 
ATOM   5352  C  C   . ILE B 2 280 ? 96.755  81.764  75.434  1.00 202.88 ? 280 ILE B C   1 
ATOM   5353  O  O   . ILE B 2 280 ? 97.527  81.017  76.030  1.00 257.64 ? 280 ILE B O   1 
ATOM   5354  C  CB  . ILE B 2 280 ? 97.242  81.228  72.953  1.00 199.10 ? 280 ILE B CB  1 
ATOM   5355  C  CG1 . ILE B 2 280 ? 96.701  80.451  71.742  1.00 337.37 ? 280 ILE B CG1 1 
ATOM   5356  C  CG2 . ILE B 2 280 ? 98.583  80.624  73.386  1.00 207.87 ? 280 ILE B CG2 1 
ATOM   5357  C  CD1 . ILE B 2 280 ? 96.509  78.941  71.928  1.00 393.74 ? 280 ILE B CD1 1 
ATOM   5358  N  N   . SER B 2 281 ? 96.396  82.967  75.929  1.00 196.47 ? 281 SER B N   1 
ATOM   5359  C  CA  . SER B 2 281 ? 96.976  83.485  77.168  1.00 232.37 ? 281 SER B CA  1 
ATOM   5360  C  C   . SER B 2 281 ? 95.983  83.515  78.330  1.00 187.26 ? 281 SER B C   1 
ATOM   5361  O  O   . SER B 2 281 ? 96.304  82.924  79.353  1.00 185.29 ? 281 SER B O   1 
ATOM   5362  C  CB  . SER B 2 281 ? 97.622  84.828  76.977  1.00 248.73 ? 281 SER B CB  1 
ATOM   5363  O  OG  . SER B 2 281 ? 96.673  85.764  76.526  1.00 246.42 ? 281 SER B OG  1 
ATOM   5364  N  N   . LEU B 2 282 ? 94.817  84.168  78.254  1.00 152.67 ? 282 LEU B N   1 
ATOM   5365  C  CA  . LEU B 2 282 ? 94.084  84.409  79.502  1.00 169.45 ? 282 LEU B CA  1 
ATOM   5366  C  C   . LEU B 2 282 ? 93.606  83.139  80.200  1.00 170.98 ? 282 LEU B C   1 
ATOM   5367  O  O   . LEU B 2 282 ? 93.629  83.070  81.432  1.00 225.56 ? 282 LEU B O   1 
ATOM   5368  C  CB  . LEU B 2 282 ? 92.896  85.342  79.274  1.00 144.82 ? 282 LEU B CB  1 
ATOM   5369  C  CG  . LEU B 2 282 ? 93.229  86.773  79.604  1.00 158.70 ? 282 LEU B CG  1 
ATOM   5370  C  CD1 . LEU B 2 282 ? 93.942  87.384  78.410  1.00 164.32 ? 282 LEU B CD1 1 
ATOM   5371  C  CD2 . LEU B 2 282 ? 91.987  87.520  80.001  1.00 173.78 ? 282 LEU B CD2 1 
ATOM   5372  N  N   . PRO B 2 283 ? 93.112  82.121  79.482  1.00 138.68 ? 283 PRO B N   1 
ATOM   5373  C  CA  . PRO B 2 283 ? 92.891  80.815  80.087  1.00 205.74 ? 283 PRO B CA  1 
ATOM   5374  C  C   . PRO B 2 283 ? 94.141  80.215  80.733  1.00 178.38 ? 283 PRO B C   1 
ATOM   5375  O  O   . PRO B 2 283 ? 93.998  79.577  81.777  1.00 242.69 ? 283 PRO B O   1 
ATOM   5376  C  CB  . PRO B 2 283 ? 92.382  79.984  78.906  1.00 282.40 ? 283 PRO B CB  1 
ATOM   5377  C  CG  . PRO B 2 283 ? 91.734  81.009  78.005  1.00 237.67 ? 283 PRO B CG  1 
ATOM   5378  C  CD  . PRO B 2 283 ? 92.681  82.175  78.091  1.00 179.95 ? 283 PRO B CD  1 
ATOM   5379  N  N   . ILE B 2 284 ? 95.326  80.425  80.143  1.00 119.49 ? 284 ILE B N   1 
ATOM   5380  C  CA  . ILE B 2 284 ? 96.579  79.937  80.722  1.00 184.90 ? 284 ILE B CA  1 
ATOM   5381  C  C   . ILE B 2 284 ? 96.898  80.664  82.034  1.00 218.45 ? 284 ILE B C   1 
ATOM   5382  O  O   . ILE B 2 284 ? 97.257  80.043  83.035  1.00 219.66 ? 284 ILE B O   1 
ATOM   5383  C  CB  . ILE B 2 284 ? 97.715  80.032  79.676  1.00 193.75 ? 284 ILE B CB  1 
ATOM   5384  C  CG1 . ILE B 2 284 ? 97.389  79.119  78.490  1.00 289.78 ? 284 ILE B CG1 1 
ATOM   5385  C  CG2 . ILE B 2 284 ? 99.111  79.778  80.237  1.00 189.80 ? 284 ILE B CG2 1 
ATOM   5386  C  CD1 . ILE B 2 284 ? 97.005  77.695  78.831  1.00 364.63 ? 284 ILE B CD1 1 
ATOM   5387  N  N   . VAL B 2 285 ? 96.745  81.983  82.026  1.00 203.26 ? 285 VAL B N   1 
ATOM   5388  C  CA  . VAL B 2 285 ? 96.898  82.780  83.224  1.00 164.88 ? 285 VAL B CA  1 
ATOM   5389  C  C   . VAL B 2 285 ? 95.922  82.316  84.298  1.00 167.61 ? 285 VAL B C   1 
ATOM   5390  O  O   . VAL B 2 285 ? 96.329  82.139  85.434  1.00 196.47 ? 285 VAL B O   1 
ATOM   5391  C  CB  . VAL B 2 285 ? 96.671  84.257  82.887  1.00 175.82 ? 285 VAL B CB  1 
ATOM   5392  C  CG1 . VAL B 2 285 ? 96.603  85.113  84.128  1.00 221.93 ? 285 VAL B CG1 1 
ATOM   5393  C  CG2 . VAL B 2 285 ? 97.757  84.770  81.958  1.00 282.33 ? 285 VAL B CG2 1 
ATOM   5394  N  N   . THR B 2 286 ? 94.640  82.131  83.952  1.00 163.89 ? 286 THR B N   1 
ATOM   5395  C  CA  . THR B 2 286 ? 93.615  81.796  84.935  1.00 183.13 ? 286 THR B CA  1 
ATOM   5396  C  C   . THR B 2 286 ? 93.925  80.466  85.612  1.00 144.52 ? 286 THR B C   1 
ATOM   5397  O  O   . THR B 2 286 ? 93.850  80.384  86.846  1.00 151.08 ? 286 THR B O   1 
ATOM   5398  C  CB  . THR B 2 286 ? 92.211  81.786  84.315  1.00 237.26 ? 286 THR B CB  1 
ATOM   5399  O  OG1 . THR B 2 286 ? 91.952  83.090  83.800  1.00 226.10 ? 286 THR B OG1 1 
ATOM   5400  C  CG2 . THR B 2 286 ? 91.107  81.431  85.289  1.00 250.42 ? 286 THR B CG2 1 
ATOM   5401  N  N   . LEU B 2 287 ? 94.275  79.458  84.806  1.00 144.01 ? 287 LEU B N   1 
ATOM   5402  C  CA  . LEU B 2 287 ? 94.723  78.188  85.354  1.00 188.44 ? 287 LEU B CA  1 
ATOM   5403  C  C   . LEU B 2 287 ? 95.899  78.406  86.319  1.00 194.66 ? 287 LEU B C   1 
ATOM   5404  O  O   . LEU B 2 287 ? 95.855  77.954  87.480  1.00 253.28 ? 287 LEU B O   1 
ATOM   5405  C  CB  . LEU B 2 287 ? 95.113  77.248  84.209  1.00 216.37 ? 287 LEU B CB  1 
ATOM   5406  C  CG  . LEU B 2 287 ? 95.835  75.971  84.654  1.00 277.97 ? 287 LEU B CG  1 
ATOM   5407  C  CD1 . LEU B 2 287 ? 94.846  75.031  85.328  1.00 348.54 ? 287 LEU B CD1 1 
ATOM   5408  C  CD2 . LEU B 2 287 ? 96.573  75.284  83.514  1.00 304.72 ? 287 LEU B CD2 1 
ATOM   5409  N  N   . VAL B 2 288 ? 96.952  79.092  85.852  1.00 154.80 ? 288 VAL B N   1 
ATOM   5410  C  CA  . VAL B 2 288 ? 98.164  79.244  86.643  1.00 174.09 ? 288 VAL B CA  1 
ATOM   5411  C  C   . VAL B 2 288 ? 97.897  79.985  87.961  1.00 160.14 ? 288 VAL B C   1 
ATOM   5412  O  O   . VAL B 2 288 ? 98.514  79.678  88.978  1.00 160.11 ? 288 VAL B O   1 
ATOM   5413  C  CB  . VAL B 2 288 ? 99.267  79.889  85.799  1.00 185.52 ? 288 VAL B CB  1 
ATOM   5414  C  CG1 . VAL B 2 288 ? 100.418 80.364  86.653  1.00 227.04 ? 288 VAL B CG1 1 
ATOM   5415  C  CG2 . VAL B 2 288 ? 99.748  78.898  84.754  1.00 235.62 ? 288 VAL B CG2 1 
ATOM   5416  N  N   . TYR B 2 289 ? 96.968  80.933  87.946  1.00 159.11 ? 289 TYR B N   1 
ATOM   5417  C  CA  . TYR B 2 289 ? 96.604  81.650  89.149  1.00 160.56 ? 289 TYR B CA  1 
ATOM   5418  C  C   . TYR B 2 289 ? 95.902  80.751  90.152  1.00 161.39 ? 289 TYR B C   1 
ATOM   5419  O  O   . TYR B 2 289 ? 96.283  80.769  91.320  1.00 224.02 ? 289 TYR B O   1 
ATOM   5420  C  CB  . TYR B 2 289 ? 95.755  82.863  88.762  1.00 148.26 ? 289 TYR B CB  1 
ATOM   5421  C  CG  . TYR B 2 289 ? 96.553  84.113  88.386  1.00 201.76 ? 289 TYR B CG  1 
ATOM   5422  C  CD1 . TYR B 2 289 ? 97.967  84.130  88.212  1.00 174.67 ? 289 TYR B CD1 1 
ATOM   5423  C  CD2 . TYR B 2 289 ? 95.860  85.315  88.220  1.00 156.65 ? 289 TYR B CD2 1 
ATOM   5424  C  CE1 . TYR B 2 289 ? 98.643  85.302  87.886  1.00 129.42 ? 289 TYR B CE1 1 
ATOM   5425  C  CE2 . TYR B 2 289 ? 96.511  86.492  87.894  1.00 155.71 ? 289 TYR B CE2 1 
ATOM   5426  C  CZ  . TYR B 2 289 ? 97.901  86.477  87.727  1.00 176.54 ? 289 TYR B CZ  1 
ATOM   5427  O  OH  . TYR B 2 289 ? 98.514  87.640  87.400  1.00 115.27 ? 289 TYR B OH  1 
ATOM   5428  N  N   . VAL B 2 290 ? 94.880  79.996  89.745  1.00 170.44 ? 290 VAL B N   1 
ATOM   5429  C  CA  . VAL B 2 290 ? 94.183  79.179  90.734  1.00 188.30 ? 290 VAL B CA  1 
ATOM   5430  C  C   . VAL B 2 290 ? 95.103  78.076  91.259  1.00 146.01 ? 290 VAL B C   1 
ATOM   5431  O  O   . VAL B 2 290 ? 95.043  77.778  92.445  1.00 202.18 ? 290 VAL B O   1 
ATOM   5432  C  CB  . VAL B 2 290 ? 92.834  78.636  90.241  1.00 229.70 ? 290 VAL B CB  1 
ATOM   5433  C  CG1 . VAL B 2 290 ? 91.911  79.800  89.930  1.00 134.25 ? 290 VAL B CG1 1 
ATOM   5434  C  CG2 . VAL B 2 290 ? 92.951  77.658  89.063  1.00 320.00 ? 290 VAL B CG2 1 
ATOM   5435  N  N   . LEU B 2 291 ? 95.962  77.503  90.415  1.00 136.49 ? 291 LEU B N   1 
ATOM   5436  C  CA  . LEU B 2 291 ? 96.964  76.554  90.900  1.00 172.17 ? 291 LEU B CA  1 
ATOM   5437  C  C   . LEU B 2 291 ? 98.005  77.211  91.815  1.00 171.72 ? 291 LEU B C   1 
ATOM   5438  O  O   . LEU B 2 291 ? 98.417  76.586  92.791  1.00 202.59 ? 291 LEU B O   1 
ATOM   5439  C  CB  . LEU B 2 291 ? 97.679  75.892  89.726  1.00 161.53 ? 291 LEU B CB  1 
ATOM   5440  C  CG  . LEU B 2 291 ? 96.840  75.005  88.820  1.00 261.67 ? 291 LEU B CG  1 
ATOM   5441  C  CD1 . LEU B 2 291 ? 97.743  74.402  87.754  1.00 308.79 ? 291 LEU B CD1 1 
ATOM   5442  C  CD2 . LEU B 2 291 ? 96.107  73.917  89.601  1.00 330.28 ? 291 LEU B CD2 1 
ATOM   5443  N  N   . THR B 2 292 ? 98.438  78.450  91.535  1.00 163.89 ? 292 THR B N   1 
ATOM   5444  C  CA  . THR B 2 292 ? 99.438  79.076  92.394  1.00 154.38 ? 292 THR B CA  1 
ATOM   5445  C  C   . THR B 2 292 ? 98.837  79.387  93.760  1.00 159.83 ? 292 THR B C   1 
ATOM   5446  O  O   . THR B 2 292 ? 99.506  79.159  94.765  1.00 242.90 ? 292 THR B O   1 
ATOM   5447  C  CB  . THR B 2 292 ? 100.010 80.340  91.762  1.00 215.13 ? 292 THR B CB  1 
ATOM   5448  O  OG1 . THR B 2 292 ? 100.628 80.000  90.526  1.00 206.55 ? 292 THR B OG1 1 
ATOM   5449  C  CG2 . THR B 2 292 ? 101.019 81.037  92.642  1.00 264.89 ? 292 THR B CG2 1 
ATOM   5450  N  N   . ASN B 2 293 ? 97.594  79.890  93.801  1.00 146.91 ? 293 ASN B N   1 
ATOM   5451  C  CA  . ASN B 2 293 ? 96.896  80.099  95.064  1.00 166.25 ? 293 ASN B CA  1 
ATOM   5452  C  C   . ASN B 2 293 ? 96.778  78.782  95.830  1.00 183.99 ? 293 ASN B C   1 
ATOM   5453  O  O   . ASN B 2 293 ? 97.052  78.759  97.028  1.00 180.37 ? 293 ASN B O   1 
ATOM   5454  C  CB  . ASN B 2 293 ? 95.553  80.806  94.868  1.00 149.06 ? 293 ASN B CB  1 
ATOM   5455  C  CG  . ASN B 2 293 ? 95.806  82.283  94.655  1.00 164.93 ? 293 ASN B CG  1 
ATOM   5456  O  OD1 . ASN B 2 293 ? 96.022  83.041  95.602  1.00 203.40 ? 293 ASN B OD1 1 
ATOM   5457  N  ND2 . ASN B 2 293 ? 95.806  82.711  93.410  1.00 167.06 ? 293 ASN B ND2 1 
ATOM   5458  N  N   . LEU B 2 294 ? 96.395  77.706  95.134  1.00 186.03 ? 294 LEU B N   1 
ATOM   5459  C  CA  . LEU B 2 294 ? 96.289  76.386  95.742  1.00 185.01 ? 294 LEU B CA  1 
ATOM   5460  C  C   . LEU B 2 294 ? 97.624  76.029  96.382  1.00 171.95 ? 294 LEU B C   1 
ATOM   5461  O  O   . LEU B 2 294 ? 97.634  75.608  97.534  1.00 241.67 ? 294 LEU B O   1 
ATOM   5462  C  CB  . LEU B 2 294 ? 95.835  75.366  94.689  1.00 228.84 ? 294 LEU B CB  1 
ATOM   5463  C  CG  . LEU B 2 294 ? 95.802  73.900  95.128  1.00 278.59 ? 294 LEU B CG  1 
ATOM   5464  C  CD1 . LEU B 2 294 ? 94.636  73.159  94.468  1.00 312.82 ? 294 LEU B CD1 1 
ATOM   5465  C  CD2 . LEU B 2 294 ? 97.135  73.196  94.825  1.00 296.52 ? 294 LEU B CD2 1 
ATOM   5466  N  N   . ALA B 2 295 ? 98.729  76.230  95.653  1.00 187.39 ? 295 ALA B N   1 
ATOM   5467  C  CA  . ALA B 2 295 ? 100.054 75.914  96.169  1.00 195.94 ? 295 ALA B CA  1 
ATOM   5468  C  C   . ALA B 2 295 ? 100.359 76.664  97.474  1.00 216.82 ? 295 ALA B C   1 
ATOM   5469  O  O   . ALA B 2 295 ? 100.808 76.036  98.421  1.00 248.53 ? 295 ALA B O   1 
ATOM   5470  C  CB  . ALA B 2 295 ? 101.081 76.181  95.106  1.00 242.12 ? 295 ALA B CB  1 
ATOM   5471  N  N   . TYR B 2 296 ? 100.099 77.975  97.565  1.00 230.59 ? 296 TYR B N   1 
ATOM   5472  C  CA  . TYR B 2 296 ? 100.297 78.717  98.806  1.00 214.33 ? 296 TYR B CA  1 
ATOM   5473  C  C   . TYR B 2 296 ? 99.502  78.118  99.965  1.00 224.08 ? 296 TYR B C   1 
ATOM   5474  O  O   . TYR B 2 296 ? 100.053 77.949  101.058 1.00 274.62 ? 296 TYR B O   1 
ATOM   5475  C  CB  . TYR B 2 296 ? 99.939  80.207  98.702  1.00 232.87 ? 296 TYR B CB  1 
ATOM   5476  C  CG  . TYR B 2 296 ? 100.768 80.963  97.683  1.00 232.91 ? 296 TYR B CG  1 
ATOM   5477  C  CD1 . TYR B 2 296 ? 102.139 80.709  97.548  1.00 186.63 ? 296 TYR B CD1 1 
ATOM   5478  C  CD2 . TYR B 2 296 ? 100.190 81.935  96.874  1.00 164.57 ? 296 TYR B CD2 1 
ATOM   5479  C  CE1 . TYR B 2 296 ? 102.920 81.384  96.625  1.00 143.21 ? 296 TYR B CE1 1 
ATOM   5480  C  CE2 . TYR B 2 296 ? 100.970 82.605  95.947  1.00 206.54 ? 296 TYR B CE2 1 
ATOM   5481  C  CZ  . TYR B 2 296 ? 102.328 82.335  95.831  1.00 186.28 ? 296 TYR B CZ  1 
ATOM   5482  O  OH  . TYR B 2 296 ? 103.068 82.990  94.906  1.00 219.03 ? 296 TYR B OH  1 
ATOM   5483  N  N   . PHE B 2 297 ? 98.230  77.786  99.740  1.00 160.24 ? 297 PHE B N   1 
ATOM   5484  C  CA  . PHE B 2 297 ? 97.435  77.204  100.807 1.00 196.58 ? 297 PHE B CA  1 
ATOM   5485  C  C   . PHE B 2 297 ? 97.905  75.824  101.312 1.00 200.17 ? 297 PHE B C   1 
ATOM   5486  O  O   . PHE B 2 297 ? 97.466  75.393  102.378 1.00 229.30 ? 297 PHE B O   1 
ATOM   5487  C  CB  . PHE B 2 297 ? 96.000  77.113  100.311 1.00 224.12 ? 297 PHE B CB  1 
ATOM   5488  C  CG  . PHE B 2 297 ? 95.334  78.425  100.004 1.00 147.92 ? 297 PHE B CG  1 
ATOM   5489  C  CD1 . PHE B 2 297 ? 95.437  79.483  100.867 1.00 138.01 ? 297 PHE B CD1 1 
ATOM   5490  C  CD2 . PHE B 2 297 ? 94.557  78.576  98.869  1.00 208.59 ? 297 PHE B CD2 1 
ATOM   5491  C  CE1 . PHE B 2 297 ? 94.784  80.670  100.590 1.00 182.57 ? 297 PHE B CE1 1 
ATOM   5492  C  CE2 . PHE B 2 297 ? 93.911  79.768  98.584  1.00 206.59 ? 297 PHE B CE2 1 
ATOM   5493  C  CZ  . PHE B 2 297 ? 94.029  80.815  99.449  1.00 207.78 ? 297 PHE B CZ  1 
ATOM   5494  N  N   . THR B 2 298 ? 98.779  75.115  100.587 1.00 221.70 ? 298 THR B N   1 
ATOM   5495  C  CA  . THR B 2 298 ? 99.368  73.883  101.096 1.00 253.46 ? 298 THR B CA  1 
ATOM   5496  C  C   . THR B 2 298 ? 100.405 74.161  102.187 1.00 213.95 ? 298 THR B C   1 
ATOM   5497  O  O   . THR B 2 298 ? 100.736 73.227  102.920 1.00 272.33 ? 298 THR B O   1 
ATOM   5498  C  CB  . THR B 2 298 ? 100.034 73.036  99.993  1.00 345.85 ? 298 THR B CB  1 
ATOM   5499  O  OG1 . THR B 2 298 ? 101.222 73.661  99.507  1.00 366.98 ? 298 THR B OG1 1 
ATOM   5500  C  CG2 . THR B 2 298 ? 99.145  72.788  98.795  1.00 387.75 ? 298 THR B CG2 1 
ATOM   5501  N  N   . THR B 2 299 ? 100.916 75.409  102.292 1.00 145.52 ? 299 THR B N   1 
ATOM   5502  C  CA  . THR B 2 299 ? 102.117 75.699  103.077 1.00 229.38 ? 299 THR B CA  1 
ATOM   5503  C  C   . THR B 2 299 ? 101.955 76.867  104.064 1.00 223.04 ? 299 THR B C   1 
ATOM   5504  O  O   . THR B 2 299 ? 102.497 76.817  105.176 1.00 185.73 ? 299 THR B O   1 
ATOM   5505  C  CB  . THR B 2 299 ? 103.301 75.930  102.131 1.00 218.00 ? 299 THR B CB  1 
ATOM   5506  O  OG1 . THR B 2 299 ? 103.600 74.675  101.521 1.00 175.04 ? 299 THR B OG1 1 
ATOM   5507  C  CG2 . THR B 2 299 ? 104.534 76.467  102.826 1.00 218.27 ? 299 THR B CG2 1 
ATOM   5508  N  N   . LEU B 2 300 ? 101.231 77.918  103.665 1.00 225.74 ? 300 LEU B N   1 
ATOM   5509  C  CA  . LEU B 2 300 ? 100.992 79.053  104.541 1.00 235.44 ? 300 LEU B CA  1 
ATOM   5510  C  C   . LEU B 2 300 ? 99.568  78.970  105.103 1.00 224.16 ? 300 LEU B C   1 
ATOM   5511  O  O   . LEU B 2 300 ? 98.580  78.925  104.352 1.00 207.00 ? 300 LEU B O   1 
ATOM   5512  C  CB  . LEU B 2 300 ? 101.224 80.354  103.759 1.00 239.53 ? 300 LEU B CB  1 
ATOM   5513  C  CG  . LEU B 2 300 ? 102.575 80.507  103.050 1.00 240.31 ? 300 LEU B CG  1 
ATOM   5514  C  CD1 . LEU B 2 300 ? 102.649 81.831  102.303 1.00 195.49 ? 300 LEU B CD1 1 
ATOM   5515  C  CD2 . LEU B 2 300 ? 103.751 80.396  104.015 1.00 277.61 ? 300 LEU B CD2 1 
ATOM   5516  N  N   . SER B 2 301 ? 99.485  78.966  106.446 1.00 200.25 ? 301 SER B N   1 
ATOM   5517  C  CA  . SER B 2 301 ? 98.224  79.064  107.173 1.00 262.68 ? 301 SER B CA  1 
ATOM   5518  C  C   . SER B 2 301 ? 97.537  80.409  106.929 1.00 225.10 ? 301 SER B C   1 
ATOM   5519  O  O   . SER B 2 301 ? 98.206  81.385  106.622 1.00 301.13 ? 301 SER B O   1 
ATOM   5520  C  CB  . SER B 2 301 ? 98.467  78.867  108.646 1.00 344.84 ? 301 SER B CB  1 
ATOM   5521  O  OG  . SER B 2 301 ? 99.214  77.678  108.896 1.00 424.21 ? 301 SER B OG  1 
ATOM   5522  N  N   . THR B 2 302 ? 96.210  80.493  107.080 1.00 173.39 ? 302 THR B N   1 
ATOM   5523  C  CA  . THR B 2 302 ? 95.473  81.724  106.776 1.00 252.13 ? 302 THR B CA  1 
ATOM   5524  C  C   . THR B 2 302 ? 96.024  82.944  107.537 1.00 260.18 ? 302 THR B C   1 
ATOM   5525  O  O   . THR B 2 302 ? 96.192  84.027  106.960 1.00 284.89 ? 302 THR B O   1 
ATOM   5526  C  CB  . THR B 2 302 ? 93.972  81.557  107.056 1.00 301.70 ? 302 THR B CB  1 
ATOM   5527  O  OG1 . THR B 2 302 ? 93.544  80.335  106.452 1.00 323.59 ? 302 THR B OG1 1 
ATOM   5528  C  CG2 . THR B 2 302 ? 93.126  82.700  106.534 1.00 257.94 ? 302 THR B CG2 1 
ATOM   5529  N  N   . GLU B 2 303 ? 96.312  82.759  108.834 1.00 240.48 ? 303 GLU B N   1 
ATOM   5530  C  CA  . GLU B 2 303 ? 96.889  83.797  109.684 1.00 270.25 ? 303 GLU B CA  1 
ATOM   5531  C  C   . GLU B 2 303 ? 98.218  84.318  109.122 1.00 263.25 ? 303 GLU B C   1 
ATOM   5532  O  O   . GLU B 2 303 ? 98.460  85.532  109.162 1.00 347.14 ? 303 GLU B O   1 
ATOM   5533  C  CB  . GLU B 2 303 ? 97.070  83.259  111.112 1.00 424.22 ? 303 GLU B CB  1 
ATOM   5534  C  CG  . GLU B 2 303 ? 97.590  84.298  112.104 1.00 527.13 ? 303 GLU B CG  1 
ATOM   5535  C  CD  . GLU B 2 303 ? 97.543  83.917  113.577 1.00 587.10 ? 303 GLU B CD  1 
ATOM   5536  O  OE1 . GLU B 2 303 ? 97.979  82.797  113.909 1.00 649.30 ? 303 GLU B OE1 1 
ATOM   5537  O  OE2 . GLU B 2 303 ? 97.077  84.746  114.393 1.00 541.88 ? 303 GLU B OE2 1 
ATOM   5538  N  N   . GLN B 2 304 ? 99.069  83.412  108.610 1.00 188.48 ? 304 GLN B N   1 
ATOM   5539  C  CA  . GLN B 2 304 ? 100.361 83.775  108.032 1.00 209.18 ? 304 GLN B CA  1 
ATOM   5540  C  C   . GLN B 2 304 ? 100.215 84.571  106.717 1.00 176.05 ? 304 GLN B C   1 
ATOM   5541  O  O   . GLN B 2 304 ? 100.907 85.558  106.531 1.00 176.95 ? 304 GLN B O   1 
ATOM   5542  C  CB  . GLN B 2 304 ? 101.234 82.520  107.888 1.00 197.97 ? 304 GLN B CB  1 
ATOM   5543  C  CG  . GLN B 2 304 ? 102.674 82.861  107.500 1.00 257.62 ? 304 GLN B CG  1 
ATOM   5544  C  CD  . GLN B 2 304 ? 103.737 81.871  107.922 1.00 264.56 ? 304 GLN B CD  1 
ATOM   5545  O  OE1 . GLN B 2 304 ? 103.456 80.797  108.454 1.00 276.26 ? 304 GLN B OE1 1 
ATOM   5546  N  NE2 . GLN B 2 304 ? 104.988 82.241  107.681 1.00 289.40 ? 304 GLN B NE2 1 
ATOM   5547  N  N   . MET B 2 305 ? 99.327  84.181  105.802 1.00 185.02 ? 305 MET B N   1 
ATOM   5548  C  CA  . MET B 2 305 ? 99.086  84.946  104.579 1.00 198.11 ? 305 MET B CA  1 
ATOM   5549  C  C   . MET B 2 305 ? 98.385  86.291  104.827 1.00 145.80 ? 305 MET B C   1 
ATOM   5550  O  O   . MET B 2 305 ? 98.578  87.216  104.047 1.00 258.60 ? 305 MET B O   1 
ATOM   5551  C  CB  . MET B 2 305 ? 98.221  84.144  103.602 1.00 212.23 ? 305 MET B CB  1 
ATOM   5552  C  CG  . MET B 2 305 ? 98.971  82.998  102.998 1.00 177.27 ? 305 MET B CG  1 
ATOM   5553  S  SD  . MET B 2 305 ? 97.954  81.993  101.917 1.00 197.83 ? 305 MET B SD  1 
ATOM   5554  C  CE  . MET B 2 305 ? 97.717  83.129  100.552 1.00 222.23 ? 305 MET B CE  1 
ATOM   5555  N  N   . LEU B 2 306 ? 97.570  86.405  105.880 1.00 134.47 ? 306 LEU B N   1 
ATOM   5556  C  CA  . LEU B 2 306 ? 96.938  87.668  106.240 1.00 194.76 ? 306 LEU B CA  1 
ATOM   5557  C  C   . LEU B 2 306 ? 97.957  88.694  106.769 1.00 185.62 ? 306 LEU B C   1 
ATOM   5558  O  O   . LEU B 2 306 ? 97.603  89.868  106.922 1.00 198.14 ? 306 LEU B O   1 
ATOM   5559  C  CB  . LEU B 2 306 ? 95.832  87.387  107.270 1.00 287.07 ? 306 LEU B CB  1 
ATOM   5560  C  CG  . LEU B 2 306 ? 94.517  86.827  106.711 1.00 289.54 ? 306 LEU B CG  1 
ATOM   5561  C  CD1 . LEU B 2 306 ? 93.610  86.321  107.833 1.00 312.58 ? 306 LEU B CD1 1 
ATOM   5562  C  CD2 . LEU B 2 306 ? 93.779  87.877  105.875 1.00 247.63 ? 306 LEU B CD2 1 
ATOM   5563  N  N   . SER B 2 307 ? 99.207  88.262  107.052 1.00 168.36 ? 307 SER B N   1 
ATOM   5564  C  CA  . SER B 2 307 ? 100.171 89.039  107.824 1.00 240.86 ? 307 SER B CA  1 
ATOM   5565  C  C   . SER B 2 307 ? 101.612 88.943  107.301 1.00 226.82 ? 307 SER B C   1 
ATOM   5566  O  O   . SER B 2 307 ? 102.559 89.277  108.027 1.00 227.06 ? 307 SER B O   1 
ATOM   5567  C  CB  . SER B 2 307 ? 100.098 88.600  109.276 1.00 312.51 ? 307 SER B CB  1 
ATOM   5568  O  OG  . SER B 2 307 ? 100.518 87.247  109.441 1.00 260.29 ? 307 SER B OG  1 
ATOM   5569  N  N   . SER B 2 308 ? 101.785 88.501  106.042 1.00 264.93 ? 308 SER B N   1 
ATOM   5570  C  CA  . SER B 2 308 ? 103.077 88.446  105.364 1.00 279.34 ? 308 SER B CA  1 
ATOM   5571  C  C   . SER B 2 308 ? 103.038 89.378  104.157 1.00 262.02 ? 308 SER B C   1 
ATOM   5572  O  O   . SER B 2 308 ? 102.138 89.278  103.324 1.00 267.56 ? 308 SER B O   1 
ATOM   5573  C  CB  . SER B 2 308 ? 103.439 87.047  104.945 1.00 209.94 ? 308 SER B CB  1 
ATOM   5574  O  OG  . SER B 2 308 ? 103.424 86.189  106.073 1.00 233.87 ? 308 SER B OG  1 
ATOM   5575  N  N   . GLU B 2 309 ? 104.038 90.268  104.054 1.00 257.76 ? 309 GLU B N   1 
ATOM   5576  C  CA  . GLU B 2 309 ? 104.006 91.372  103.102 1.00 245.87 ? 309 GLU B CA  1 
ATOM   5577  C  C   . GLU B 2 309 ? 104.710 91.014  101.793 1.00 214.42 ? 309 GLU B C   1 
ATOM   5578  O  O   . GLU B 2 309 ? 104.971 91.917  100.996 1.00 325.23 ? 309 GLU B O   1 
ATOM   5579  C  CB  . GLU B 2 309 ? 104.626 92.616  103.749 1.00 347.48 ? 309 GLU B CB  1 
ATOM   5580  C  CG  . GLU B 2 309 ? 103.880 93.095  104.997 1.00 469.78 ? 309 GLU B CG  1 
ATOM   5581  C  CD  . GLU B 2 309 ? 102.378 93.305  104.850 1.00 499.02 ? 309 GLU B CD  1 
ATOM   5582  O  OE1 . GLU B 2 309 ? 101.958 93.819  103.794 1.00 533.07 ? 309 GLU B OE1 1 
ATOM   5583  O  OE2 . GLU B 2 309 ? 101.627 92.959  105.791 1.00 487.65 ? 309 GLU B OE2 1 
ATOM   5584  N  N   . ALA B 2 310 ? 104.999 89.720  101.557 1.00 216.80 ? 310 ALA B N   1 
ATOM   5585  C  CA  . ALA B 2 310 ? 105.644 89.265  100.334 1.00 237.30 ? 310 ALA B CA  1 
ATOM   5586  C  C   . ALA B 2 310 ? 105.406 87.770  100.142 1.00 150.35 ? 310 ALA B C   1 
ATOM   5587  O  O   . ALA B 2 310 ? 106.343 87.005  100.192 1.00 112.75 ? 310 ALA B O   1 
ATOM   5588  C  CB  . ALA B 2 310 ? 107.120 89.595  100.415 1.00 329.25 ? 310 ALA B CB  1 
ATOM   5589  N  N   . VAL B 2 311 ? 104.153 87.374  99.893  1.00 163.14 ? 311 VAL B N   1 
ATOM   5590  C  CA  . VAL B 2 311 ? 103.637 86.011  100.081 1.00 148.39 ? 311 VAL B CA  1 
ATOM   5591  C  C   . VAL B 2 311 ? 104.533 84.921  99.477  1.00 107.58 ? 311 VAL B C   1 
ATOM   5592  O  O   . VAL B 2 311 ? 104.791 83.913  100.093 1.00 109.44 ? 311 VAL B O   1 
ATOM   5593  C  CB  . VAL B 2 311 ? 102.205 85.891  99.509  1.00 141.08 ? 311 VAL B CB  1 
ATOM   5594  C  CG1 . VAL B 2 311 ? 101.742 84.456  99.578  1.00 131.53 ? 311 VAL B CG1 1 
ATOM   5595  C  CG2 . VAL B 2 311 ? 101.219 86.822  100.209 1.00 140.16 ? 311 VAL B CG2 1 
ATOM   5596  N  N   . ALA B 2 312 ? 105.032 85.128  98.267  1.00 146.51 ? 312 ALA B N   1 
ATOM   5597  C  CA  . ALA B 2 312 ? 105.843 84.141  97.587  1.00 140.21 ? 312 ALA B CA  1 
ATOM   5598  C  C   . ALA B 2 312 ? 107.154 83.900  98.300  1.00 124.33 ? 312 ALA B C   1 
ATOM   5599  O  O   . ALA B 2 312 ? 107.676 82.798  98.210  1.00 199.60 ? 312 ALA B O   1 
ATOM   5600  C  CB  . ALA B 2 312 ? 106.096 84.601  96.177  1.00 205.35 ? 312 ALA B CB  1 
ATOM   5601  N  N   . VAL B 2 313 ? 107.689 84.908  98.989  1.00 128.97 ? 313 VAL B N   1 
ATOM   5602  C  CA  . VAL B 2 313 ? 108.976 84.783  99.659  1.00 153.62 ? 313 VAL B CA  1 
ATOM   5603  C  C   . VAL B 2 313 ? 108.827 83.866  100.878 1.00 194.37 ? 313 VAL B C   1 
ATOM   5604  O  O   . VAL B 2 313 ? 109.754 83.101  101.130 1.00 191.13 ? 313 VAL B O   1 
ATOM   5605  C  CB  . VAL B 2 313 ? 109.530 86.170  100.035 1.00 164.75 ? 313 VAL B CB  1 
ATOM   5606  C  CG1 . VAL B 2 313 ? 110.872 86.108  100.754 1.00 193.64 ? 313 VAL B CG1 1 
ATOM   5607  C  CG2 . VAL B 2 313 ? 109.614 87.043  98.802  1.00 197.76 ? 313 VAL B CG2 1 
ATOM   5608  N  N   . ASP B 2 314 ? 107.697 83.929  101.621 1.00 183.75 ? 314 ASP B N   1 
ATOM   5609  C  CA  . ASP B 2 314 ? 107.463 83.022  102.739 1.00 193.16 ? 314 ASP B CA  1 
ATOM   5610  C  C   . ASP B 2 314 ? 107.368 81.570  102.274 1.00 169.54 ? 314 ASP B C   1 
ATOM   5611  O  O   . ASP B 2 314 ? 107.962 80.696  102.898 1.00 197.62 ? 314 ASP B O   1 
ATOM   5612  C  CB  . ASP B 2 314 ? 106.240 83.448  103.556 1.00 256.08 ? 314 ASP B CB  1 
ATOM   5613  C  CG  . ASP B 2 314 ? 106.604 84.349  104.720 1.00 371.76 ? 314 ASP B CG  1 
ATOM   5614  O  OD1 . ASP B 2 314 ? 107.404 85.286  104.480 1.00 365.43 ? 314 ASP B OD1 1 
ATOM   5615  O  OD2 . ASP B 2 314 ? 106.064 84.116  105.851 1.00 507.44 ? 314 ASP B OD2 1 
ATOM   5616  N  N   . PHE B 2 315 ? 106.632 81.337  101.190 1.00 138.66 ? 315 PHE B N   1 
ATOM   5617  C  CA  . PHE B 2 315 ? 106.605 80.030  100.552 1.00 155.77 ? 315 PHE B CA  1 
ATOM   5618  C  C   . PHE B 2 315 ? 108.014 79.589  100.096 1.00 133.47 ? 315 PHE B C   1 
ATOM   5619  O  O   . PHE B 2 315 ? 108.363 78.434  100.199 1.00 123.09 ? 315 PHE B O   1 
ATOM   5620  C  CB  . PHE B 2 315 ? 105.584 80.076  99.417  1.00 159.98 ? 315 PHE B CB  1 
ATOM   5621  C  CG  . PHE B 2 315 ? 105.398 78.799  98.643  1.00 200.34 ? 315 PHE B CG  1 
ATOM   5622  C  CD1 . PHE B 2 315 ? 106.285 78.403  97.624  1.00 230.69 ? 315 PHE B CD1 1 
ATOM   5623  C  CD2 . PHE B 2 315 ? 104.308 77.996  98.936  1.00 141.71 ? 315 PHE B CD2 1 
ATOM   5624  C  CE1 . PHE B 2 315 ? 106.083 77.220  96.926  1.00 213.66 ? 315 PHE B CE1 1 
ATOM   5625  C  CE2 . PHE B 2 315 ? 104.117 76.807  98.245  1.00 191.15 ? 315 PHE B CE2 1 
ATOM   5626  C  CZ  . PHE B 2 315 ? 104.996 76.421  97.249  1.00 230.39 ? 315 PHE B CZ  1 
ATOM   5627  N  N   . GLY B 2 316 ? 108.841 80.507  99.606  1.00 158.16 ? 316 GLY B N   1 
ATOM   5628  C  CA  . GLY B 2 316 ? 110.230 80.223  99.278  1.00 185.09 ? 316 GLY B CA  1 
ATOM   5629  C  C   . GLY B 2 316 ? 111.040 79.796  100.499 1.00 184.98 ? 316 GLY B C   1 
ATOM   5630  O  O   . GLY B 2 316 ? 111.749 78.801  100.429 1.00 253.40 ? 316 GLY B O   1 
ATOM   5631  N  N   . ASN B 2 317 ? 110.910 80.529  101.610 1.00 143.03 ? 317 ASN B N   1 
ATOM   5632  C  CA  . ASN B 2 317 ? 111.609 80.210  102.848 1.00 220.55 ? 317 ASN B CA  1 
ATOM   5633  C  C   . ASN B 2 317 ? 111.266 78.814  103.384 1.00 262.07 ? 317 ASN B C   1 
ATOM   5634  O  O   . ASN B 2 317 ? 112.162 78.114  103.865 1.00 237.35 ? 317 ASN B O   1 
ATOM   5635  C  CB  . ASN B 2 317 ? 111.344 81.294  103.897 1.00 243.67 ? 317 ASN B CB  1 
ATOM   5636  C  CG  . ASN B 2 317 ? 112.109 82.580  103.633 1.00 292.21 ? 317 ASN B CG  1 
ATOM   5637  O  OD1 . ASN B 2 317 ? 113.172 82.590  103.008 1.00 214.45 ? 317 ASN B OD1 1 
ATOM   5638  N  ND2 . ASN B 2 317 ? 111.581 83.690  104.125 1.00 379.32 ? 317 ASN B ND2 1 
ATOM   5639  N  N   . TYR B 2 318 ? 109.989 78.413  103.306 1.00 247.66 ? 318 TYR B N   1 
ATOM   5640  C  CA  . TYR B 2 318 ? 109.547 77.129  103.833 1.00 238.15 ? 318 TYR B CA  1 
ATOM   5641  C  C   . TYR B 2 318 ? 110.149 75.945  103.072 1.00 220.35 ? 318 TYR B C   1 
ATOM   5642  O  O   . TYR B 2 318 ? 110.545 74.969  103.715 1.00 237.37 ? 318 TYR B O   1 
ATOM   5643  C  CB  . TYR B 2 318 ? 108.016 77.089  103.802 1.00 209.79 ? 318 TYR B CB  1 
ATOM   5644  C  CG  . TYR B 2 318 ? 107.412 75.919  104.560 1.00 279.33 ? 318 TYR B CG  1 
ATOM   5645  C  CD1 . TYR B 2 318 ? 107.281 74.662  103.970 1.00 227.12 ? 318 TYR B CD1 1 
ATOM   5646  C  CD2 . TYR B 2 318 ? 106.977 76.069  105.877 1.00 382.58 ? 318 TYR B CD2 1 
ATOM   5647  C  CE1 . TYR B 2 318 ? 106.734 73.589  104.661 1.00 237.19 ? 318 TYR B CE1 1 
ATOM   5648  C  CE2 . TYR B 2 318 ? 106.428 75.005  106.579 1.00 417.08 ? 318 TYR B CE2 1 
ATOM   5649  C  CZ  . TYR B 2 318 ? 106.306 73.763  105.971 1.00 362.57 ? 318 TYR B CZ  1 
ATOM   5650  O  OH  . TYR B 2 318 ? 105.762 72.737  106.689 1.00 418.78 ? 318 TYR B OH  1 
ATOM   5651  N  N   . HIS B 2 319 ? 110.197 76.021  101.728 1.00 205.40 ? 319 HIS B N   1 
ATOM   5652  C  CA  . HIS B 2 319 ? 110.519 74.872  100.891 1.00 187.21 ? 319 HIS B CA  1 
ATOM   5653  C  C   . HIS B 2 319 ? 112.006 74.776  100.521 1.00 182.10 ? 319 HIS B C   1 
ATOM   5654  O  O   . HIS B 2 319 ? 112.528 73.666  100.468 1.00 249.64 ? 319 HIS B O   1 
ATOM   5655  C  CB  . HIS B 2 319 ? 109.657 74.868  99.626  1.00 198.96 ? 319 HIS B CB  1 
ATOM   5656  C  CG  . HIS B 2 319 ? 108.218 74.597  99.914  1.00 196.34 ? 319 HIS B CG  1 
ATOM   5657  N  ND1 . HIS B 2 319 ? 107.760 73.381  100.371 1.00 222.02 ? 319 HIS B ND1 1 
ATOM   5658  C  CD2 . HIS B 2 319 ? 107.124 75.374  99.810  1.00 224.21 ? 319 HIS B CD2 1 
ATOM   5659  C  CE1 . HIS B 2 319 ? 106.439 73.433  100.534 1.00 201.29 ? 319 HIS B CE1 1 
ATOM   5660  N  NE2 . HIS B 2 319 ? 106.028 74.633  100.201 1.00 188.05 ? 319 HIS B NE2 1 
ATOM   5661  N  N   . LEU B 2 320 ? 112.687 75.893  100.237 1.00 205.82 ? 320 LEU B N   1 
ATOM   5662  C  CA  . LEU B 2 320 ? 113.988 75.834  99.565  1.00 240.09 ? 320 LEU B CA  1 
ATOM   5663  C  C   . LEU B 2 320 ? 115.162 76.070  100.523 1.00 234.73 ? 320 LEU B C   1 
ATOM   5664  O  O   . LEU B 2 320 ? 116.314 75.861  100.108 1.00 169.99 ? 320 LEU B O   1 
ATOM   5665  C  CB  . LEU B 2 320 ? 114.027 76.860  98.421  1.00 259.23 ? 320 LEU B CB  1 
ATOM   5666  C  CG  . LEU B 2 320 ? 112.902 76.785  97.391  1.00 256.56 ? 320 LEU B CG  1 
ATOM   5667  C  CD1 . LEU B 2 320 ? 113.121 77.828  96.306  1.00 226.51 ? 320 LEU B CD1 1 
ATOM   5668  C  CD2 . LEU B 2 320 ? 112.783 75.380  96.816  1.00 338.98 ? 320 LEU B CD2 1 
ATOM   5669  N  N   . GLY B 2 321 ? 114.887 76.506  101.771 1.00 226.78 ? 321 GLY B N   1 
ATOM   5670  C  CA  . GLY B 2 321 ? 115.921 76.675  102.788 1.00 306.11 ? 321 GLY B CA  1 
ATOM   5671  C  C   . GLY B 2 321 ? 117.071 77.582  102.336 1.00 266.57 ? 321 GLY B C   1 
ATOM   5672  O  O   . GLY B 2 321 ? 116.857 78.766  102.129 1.00 303.78 ? 321 GLY B O   1 
ATOM   5673  N  N   . VAL B 2 322 ? 118.275 77.011  102.160 1.00 208.62 ? 322 VAL B N   1 
ATOM   5674  C  CA  . VAL B 2 322 ? 119.469 77.740  101.745 1.00 216.53 ? 322 VAL B CA  1 
ATOM   5675  C  C   . VAL B 2 322 ? 119.240 78.382  100.375 1.00 225.70 ? 322 VAL B C   1 
ATOM   5676  O  O   . VAL B 2 322 ? 119.784 79.460  100.112 1.00 245.38 ? 322 VAL B O   1 
ATOM   5677  C  CB  . VAL B 2 322 ? 120.721 76.829  101.732 1.00 305.46 ? 322 VAL B CB  1 
ATOM   5678  C  CG1 . VAL B 2 322 ? 121.972 77.538  101.215 1.00 283.58 ? 322 VAL B CG1 1 
ATOM   5679  C  CG2 . VAL B 2 322 ? 121.006 76.226  103.103 1.00 388.30 ? 322 VAL B CG2 1 
ATOM   5680  N  N   . MET B 2 323 ? 118.432 77.736  99.515  1.00 228.17 ? 323 MET B N   1 
ATOM   5681  C  CA  . MET B 2 323 ? 118.161 78.238  98.167  1.00 274.16 ? 323 MET B CA  1 
ATOM   5682  C  C   . MET B 2 323 ? 116.934 79.172  98.080  1.00 218.09 ? 323 MET B C   1 
ATOM   5683  O  O   . MET B 2 323 ? 116.493 79.490  96.975  1.00 201.70 ? 323 MET B O   1 
ATOM   5684  C  CB  . MET B 2 323 ? 117.989 77.039  97.220  1.00 315.78 ? 323 MET B CB  1 
ATOM   5685  C  CG  . MET B 2 323 ? 119.279 76.240  97.008  1.00 360.52 ? 323 MET B CG  1 
ATOM   5686  S  SD  . MET B 2 323 ? 120.625 77.176  96.184  1.00 429.89 ? 323 MET B SD  1 
ATOM   5687  C  CE  . MET B 2 323 ? 121.516 75.841  95.378  1.00 331.08 ? 323 MET B CE  1 
ATOM   5688  N  N   . SER B 2 324 ? 116.392 79.649  99.210  1.00 214.03 ? 324 SER B N   1 
ATOM   5689  C  CA  . SER B 2 324 ? 115.184 80.463  99.236  1.00 226.07 ? 324 SER B CA  1 
ATOM   5690  C  C   . SER B 2 324 ? 115.309 81.689  98.347  1.00 198.05 ? 324 SER B C   1 
ATOM   5691  O  O   . SER B 2 324 ? 114.298 82.113  97.785  1.00 256.42 ? 324 SER B O   1 
ATOM   5692  C  CB  . SER B 2 324 ? 114.838 80.865  100.655 1.00 290.30 ? 324 SER B CB  1 
ATOM   5693  O  OG  . SER B 2 324 ? 113.700 81.718  100.681 1.00 266.19 ? 324 SER B OG  1 
ATOM   5694  N  N   . TRP B 2 325 ? 116.524 82.242  98.233  1.00 160.36 ? 325 TRP B N   1 
ATOM   5695  C  CA  . TRP B 2 325 ? 116.787 83.463  97.465  1.00 206.12 ? 325 TRP B CA  1 
ATOM   5696  C  C   . TRP B 2 325 ? 116.346 83.399  95.998  1.00 148.62 ? 325 TRP B C   1 
ATOM   5697  O  O   . TRP B 2 325 ? 116.130 84.440  95.365  1.00 131.06 ? 325 TRP B O   1 
ATOM   5698  C  CB  . TRP B 2 325 ? 118.282 83.801  97.536  1.00 226.91 ? 325 TRP B CB  1 
ATOM   5699  C  CG  . TRP B 2 325 ? 119.162 82.723  96.976  1.00 197.63 ? 325 TRP B CG  1 
ATOM   5700  C  CD1 . TRP B 2 325 ? 119.738 81.714  97.688  1.00 235.63 ? 325 TRP B CD1 1 
ATOM   5701  C  CD2 . TRP B 2 325 ? 119.560 82.538  95.604  1.00 186.26 ? 325 TRP B CD2 1 
ATOM   5702  N  NE1 . TRP B 2 325 ? 120.473 80.907  96.866  1.00 244.29 ? 325 TRP B NE1 1 
ATOM   5703  C  CE2 . TRP B 2 325 ? 120.382 81.387  95.583  1.00 245.21 ? 325 TRP B CE2 1 
ATOM   5704  C  CE3 . TRP B 2 325 ? 119.309 83.216  94.406  1.00 186.75 ? 325 TRP B CE3 1 
ATOM   5705  C  CZ2 . TRP B 2 325 ? 120.949 80.909  94.401  1.00 296.11 ? 325 TRP B CZ2 1 
ATOM   5706  C  CZ3 . TRP B 2 325 ? 119.869 82.740  93.240  1.00 212.88 ? 325 TRP B CZ3 1 
ATOM   5707  C  CH2 . TRP B 2 325 ? 120.680 81.606  93.239  1.00 268.20 ? 325 TRP B CH2 1 
ATOM   5708  N  N   . ILE B 2 326 ? 116.210 82.188  95.460  1.00 141.88 ? 326 ILE B N   1 
ATOM   5709  C  CA  . ILE B 2 326 ? 115.713 81.993  94.107  1.00 172.05 ? 326 ILE B CA  1 
ATOM   5710  C  C   . ILE B 2 326 ? 114.346 82.664  93.872  1.00 155.29 ? 326 ILE B C   1 
ATOM   5711  O  O   . ILE B 2 326 ? 114.151 83.250  92.808  1.00 195.59 ? 326 ILE B O   1 
ATOM   5712  C  CB  . ILE B 2 326 ? 115.751 80.484  93.795  1.00 180.98 ? 326 ILE B CB  1 
ATOM   5713  C  CG1 . ILE B 2 326 ? 117.215 80.086  93.557  1.00 204.72 ? 326 ILE B CG1 1 
ATOM   5714  C  CG2 . ILE B 2 326 ? 114.843 80.065  92.644  1.00 190.48 ? 326 ILE B CG2 1 
ATOM   5715  C  CD1 . ILE B 2 326 ? 117.439 78.613  93.260  1.00 305.72 ? 326 ILE B CD1 1 
ATOM   5716  N  N   . ILE B 2 327 ? 113.404 82.592  94.825  1.00 119.82 ? 327 ILE B N   1 
ATOM   5717  C  CA  . ILE B 2 327 ? 112.064 83.119  94.593  1.00 137.41 ? 327 ILE B CA  1 
ATOM   5718  C  C   . ILE B 2 327 ? 112.055 84.651  94.576  1.00 148.50 ? 327 ILE B C   1 
ATOM   5719  O  O   . ILE B 2 327 ? 111.487 85.208  93.626  1.00 236.76 ? 327 ILE B O   1 
ATOM   5720  C  CB  . ILE B 2 327 ? 111.003 82.523  95.531  1.00 139.56 ? 327 ILE B CB  1 
ATOM   5721  C  CG1 . ILE B 2 327 ? 111.043 80.989  95.450  1.00 204.43 ? 327 ILE B CG1 1 
ATOM   5722  C  CG2 . ILE B 2 327 ? 109.609 83.062  95.203  1.00 127.70 ? 327 ILE B CG2 1 
ATOM   5723  C  CD1 . ILE B 2 327 ? 110.956 80.372  94.026  1.00 151.60 ? 327 ILE B CD1 1 
ATOM   5724  N  N   . PRO B 2 328 ? 112.644 85.389  95.541  1.00 139.58 ? 328 PRO B N   1 
ATOM   5725  C  CA  . PRO B 2 328 ? 112.853 86.832  95.371  1.00 151.26 ? 328 PRO B CA  1 
ATOM   5726  C  C   . PRO B 2 328 ? 113.439 87.220  94.013  1.00 132.07 ? 328 PRO B C   1 
ATOM   5727  O  O   . PRO B 2 328 ? 112.931 88.156  93.391  1.00 135.31 ? 328 PRO B O   1 
ATOM   5728  C  CB  . PRO B 2 328 ? 113.801 87.205  96.524  1.00 162.79 ? 328 PRO B CB  1 
ATOM   5729  C  CG  . PRO B 2 328 ? 113.431 86.204  97.590  1.00 206.05 ? 328 PRO B CG  1 
ATOM   5730  C  CD  . PRO B 2 328 ? 113.089 84.917  96.850  1.00 157.51 ? 328 PRO B CD  1 
ATOM   5731  N  N   . VAL B 2 329 ? 114.486 86.519  93.544  1.00 107.32 ? 329 VAL B N   1 
ATOM   5732  C  CA  . VAL B 2 329 ? 115.105 86.913  92.292  1.00 110.39 ? 329 VAL B CA  1 
ATOM   5733  C  C   . VAL B 2 329 ? 114.122 86.675  91.158  1.00 123.12 ? 329 VAL B C   1 
ATOM   5734  O  O   . VAL B 2 329 ? 114.034 87.514  90.276  1.00 162.60 ? 329 VAL B O   1 
ATOM   5735  C  CB  . VAL B 2 329 ? 116.453 86.228  92.061  1.00 130.22 ? 329 VAL B CB  1 
ATOM   5736  C  CG1 . VAL B 2 329 ? 117.007 86.445  90.680  1.00 181.42 ? 329 VAL B CG1 1 
ATOM   5737  C  CG2 . VAL B 2 329 ? 117.479 86.734  93.049  1.00 161.14 ? 329 VAL B CG2 1 
ATOM   5738  N  N   . PHE B 2 330 ? 113.377 85.578  91.171  1.00 133.23 ? 330 PHE B N   1 
ATOM   5739  C  CA  . PHE B 2 330 ? 112.371 85.393  90.125  1.00 185.39 ? 330 PHE B CA  1 
ATOM   5740  C  C   . PHE B 2 330 ? 111.254 86.455  90.162  1.00 155.60 ? 330 PHE B C   1 
ATOM   5741  O  O   . PHE B 2 330 ? 110.843 86.870  89.097  1.00 177.89 ? 330 PHE B O   1 
ATOM   5742  C  CB  . PHE B 2 330 ? 111.760 83.993  90.180  1.00 217.20 ? 330 PHE B CB  1 
ATOM   5743  C  CG  . PHE B 2 330 ? 112.534 82.885  89.504  1.00 210.00 ? 330 PHE B CG  1 
ATOM   5744  C  CD1 . PHE B 2 330 ? 113.043 83.028  88.223  1.00 251.01 ? 330 PHE B CD1 1 
ATOM   5745  C  CD2 . PHE B 2 330 ? 112.741 81.672  90.162  1.00 348.26 ? 330 PHE B CD2 1 
ATOM   5746  C  CE1 . PHE B 2 330 ? 113.748 81.992  87.624  1.00 363.41 ? 330 PHE B CE1 1 
ATOM   5747  C  CE2 . PHE B 2 330 ? 113.436 80.630  89.557  1.00 398.49 ? 330 PHE B CE2 1 
ATOM   5748  C  CZ  . PHE B 2 330 ? 113.945 80.797  88.287  1.00 387.01 ? 330 PHE B CZ  1 
ATOM   5749  N  N   . VAL B 2 331 ? 110.759 86.913  91.323  1.00 115.97 ? 331 VAL B N   1 
ATOM   5750  C  CA  . VAL B 2 331 ? 109.831 88.050  91.375  1.00 111.40 ? 331 VAL B CA  1 
ATOM   5751  C  C   . VAL B 2 331 ? 110.468 89.293  90.742  1.00 122.91 ? 331 VAL B C   1 
ATOM   5752  O  O   . VAL B 2 331 ? 109.814 90.088  90.059  1.00 140.83 ? 331 VAL B O   1 
ATOM   5753  C  CB  . VAL B 2 331 ? 109.425 88.379  92.823  1.00 145.17 ? 331 VAL B CB  1 
ATOM   5754  C  CG1 . VAL B 2 331 ? 108.636 89.676  92.979  1.00 149.36 ? 331 VAL B CG1 1 
ATOM   5755  C  CG2 . VAL B 2 331 ? 108.663 87.201  93.396  1.00 206.42 ? 331 VAL B CG2 1 
ATOM   5756  N  N   . GLY B 2 332 ? 111.766 89.483  90.955  1.00 134.48 ? 332 GLY B N   1 
ATOM   5757  C  CA  . GLY B 2 332 ? 112.445 90.609  90.342  1.00 147.59 ? 332 GLY B CA  1 
ATOM   5758  C  C   . GLY B 2 332 ? 112.433 90.493  88.825  1.00 145.04 ? 332 GLY B C   1 
ATOM   5759  O  O   . GLY B 2 332 ? 111.870 91.347  88.168  1.00 104.03 ? 332 GLY B O   1 
ATOM   5760  N  N   . LEU B 2 333 ? 113.041 89.430  88.282  1.00 151.45 ? 333 LEU B N   1 
ATOM   5761  C  CA  . LEU B 2 333 ? 113.150 89.224  86.846  1.00 130.72 ? 333 LEU B CA  1 
ATOM   5762  C  C   . LEU B 2 333 ? 111.770 89.214  86.199  1.00 112.04 ? 333 LEU B C   1 
ATOM   5763  O  O   . LEU B 2 333 ? 111.609 89.678  85.067  1.00 125.84 ? 333 LEU B O   1 
ATOM   5764  C  CB  . LEU B 2 333 ? 113.938 87.936  86.597  1.00 110.53 ? 333 LEU B CB  1 
ATOM   5765  C  CG  . LEU B 2 333 ? 115.369 87.990  87.164  1.00 174.86 ? 333 LEU B CG  1 
ATOM   5766  C  CD1 . LEU B 2 333 ? 116.097 86.701  86.795  1.00 284.71 ? 333 LEU B CD1 1 
ATOM   5767  C  CD2 . LEU B 2 333 ? 116.211 89.257  86.764  1.00 138.99 ? 333 LEU B CD2 1 
ATOM   5768  N  N   . SER B 2 334 ? 110.795 88.687  86.920  1.00 116.04 ? 334 SER B N   1 
ATOM   5769  C  CA  . SER B 2 334 ? 109.394 88.776  86.552  1.00 132.48 ? 334 SER B CA  1 
ATOM   5770  C  C   . SER B 2 334 ? 108.924 90.216  86.324  1.00 94.56  ? 334 SER B C   1 
ATOM   5771  O  O   . SER B 2 334 ? 108.153 90.465  85.408  1.00 115.09 ? 334 SER B O   1 
ATOM   5772  C  CB  . SER B 2 334 ? 108.597 88.059  87.637  1.00 202.67 ? 334 SER B CB  1 
ATOM   5773  O  OG  . SER B 2 334 ? 107.209 88.301  87.582  1.00 149.24 ? 334 SER B OG  1 
ATOM   5774  N  N   . CYS B 2 335 ? 109.341 91.170  87.152  1.00 129.77 ? 335 CYS B N   1 
ATOM   5775  C  CA  . CYS B 2 335 ? 108.914 92.554  86.997  1.00 144.63 ? 335 CYS B CA  1 
ATOM   5776  C  C   . CYS B 2 335 ? 109.679 93.252  85.876  1.00 148.50 ? 335 CYS B C   1 
ATOM   5777  O  O   . CYS B 2 335 ? 109.117 94.133  85.242  1.00 133.34 ? 335 CYS B O   1 
ATOM   5778  C  CB  . CYS B 2 335 ? 109.077 93.289  88.315  1.00 134.65 ? 335 CYS B CB  1 
ATOM   5779  S  SG  . CYS B 2 335 ? 107.849 92.698  89.478  1.00 170.12 ? 335 CYS B SG  1 
ATOM   5780  N  N   . PHE B 2 336 ? 110.935 92.861  85.627  1.00 114.99 ? 336 PHE B N   1 
ATOM   5781  C  CA  . PHE B 2 336 ? 111.702 93.404  84.526  1.00 119.99 ? 336 PHE B CA  1 
ATOM   5782  C  C   . PHE B 2 336 ? 110.947 93.273  83.206  1.00 141.53 ? 336 PHE B C   1 
ATOM   5783  O  O   . PHE B 2 336 ? 110.823 94.250  82.460  1.00 93.53  ? 336 PHE B O   1 
ATOM   5784  C  CB  . PHE B 2 336 ? 113.044 92.668  84.475  1.00 137.55 ? 336 PHE B CB  1 
ATOM   5785  C  CG  . PHE B 2 336 ? 114.091 93.319  83.619  1.00 180.29 ? 336 PHE B CG  1 
ATOM   5786  C  CD1 . PHE B 2 336 ? 114.747 94.489  84.025  1.00 183.78 ? 336 PHE B CD1 1 
ATOM   5787  C  CD2 . PHE B 2 336 ? 114.404 92.757  82.406  1.00 140.65 ? 336 PHE B CD2 1 
ATOM   5788  C  CE1 . PHE B 2 336 ? 115.694 95.084  83.217  1.00 128.55 ? 336 PHE B CE1 1 
ATOM   5789  C  CE2 . PHE B 2 336 ? 115.363 93.342  81.605  1.00 185.19 ? 336 PHE B CE2 1 
ATOM   5790  C  CZ  . PHE B 2 336 ? 116.001 94.495  82.011  1.00 201.34 ? 336 PHE B CZ  1 
ATOM   5791  N  N   . GLY B 2 337 ? 110.451 92.048  82.947  1.00 181.08 ? 337 GLY B N   1 
ATOM   5792  C  CA  . GLY B 2 337 ? 109.539 91.678  81.859  1.00 179.66 ? 337 GLY B CA  1 
ATOM   5793  C  C   . GLY B 2 337 ? 108.322 92.586  81.707  1.00 134.04 ? 337 GLY B C   1 
ATOM   5794  O  O   . GLY B 2 337 ? 107.932 92.946  80.594  1.00 177.44 ? 337 GLY B O   1 
ATOM   5795  N  N   . SER B 2 338 ? 107.746 92.971  82.829  1.00 116.88 ? 338 SER B N   1 
ATOM   5796  C  CA  . SER B 2 338 ? 106.607 93.860  82.829  1.00 131.28 ? 338 SER B CA  1 
ATOM   5797  C  C   . SER B 2 338 ? 106.999 95.316  82.517  1.00 119.06 ? 338 SER B C   1 
ATOM   5798  O  O   . SER B 2 338 ? 106.197 96.056  81.935  1.00 130.82 ? 338 SER B O   1 
ATOM   5799  C  CB  . SER B 2 338 ? 105.849 93.731  84.153  1.00 152.11 ? 338 SER B CB  1 
ATOM   5800  O  OG  . SER B 2 338 ? 104.661 94.553  84.167  1.00 176.31 ? 338 SER B OG  1 
ATOM   5801  N  N   . VAL B 2 339 ? 108.189 95.768  82.932  1.00 92.51  ? 339 VAL B N   1 
ATOM   5802  C  CA  . VAL B 2 339 ? 108.629 97.086  82.560  1.00 98.23  ? 339 VAL B CA  1 
ATOM   5803  C  C   . VAL B 2 339 ? 108.808 97.070  81.055  1.00 122.46 ? 339 VAL B C   1 
ATOM   5804  O  O   . VAL B 2 339 ? 108.395 98.019  80.384  1.00 180.77 ? 339 VAL B O   1 
ATOM   5805  C  CB  . VAL B 2 339 ? 109.925 97.532  83.251  1.00 110.52 ? 339 VAL B CB  1 
ATOM   5806  C  CG1 . VAL B 2 339 ? 110.310 98.949  82.782  1.00 121.44 ? 339 VAL B CG1 1 
ATOM   5807  C  CG2 . VAL B 2 339 ? 109.870 97.500  84.781  1.00 147.69 ? 339 VAL B CG2 1 
ATOM   5808  N  N   . ASN B 2 340 ? 109.444 96.032  80.509  1.00 119.05 ? 340 ASN B N   1 
ATOM   5809  C  CA  . ASN B 2 340 ? 109.711 96.007  79.072  1.00 141.22 ? 340 ASN B CA  1 
ATOM   5810  C  C   . ASN B 2 340 ? 108.424 95.985  78.245  1.00 110.06 ? 340 ASN B C   1 
ATOM   5811  O  O   . ASN B 2 340 ? 108.237 96.756  77.309  1.00 100.94 ? 340 ASN B O   1 
ATOM   5812  C  CB  . ASN B 2 340 ? 110.552 94.798  78.697  1.00 172.86 ? 340 ASN B CB  1 
ATOM   5813  C  CG  . ASN B 2 340 ? 110.830 94.721  77.212  1.00 146.08 ? 340 ASN B CG  1 
ATOM   5814  O  OD1 . ASN B 2 340 ? 111.110 95.755  76.597  1.00 211.00 ? 340 ASN B OD1 1 
ATOM   5815  N  ND2 . ASN B 2 340 ? 110.764 93.511  76.649  1.00 104.80 ? 340 ASN B ND2 1 
ATOM   5816  N  N   . GLY B 2 341 ? 107.522 95.106  78.607  1.00 107.51 ? 341 GLY B N   1 
ATOM   5817  C  CA  . GLY B 2 341 ? 106.232 95.087  77.960  1.00 146.74 ? 341 GLY B CA  1 
ATOM   5818  C  C   . GLY B 2 341 ? 105.460 96.406  78.046  1.00 128.53 ? 341 GLY B C   1 
ATOM   5819  O  O   . GLY B 2 341 ? 104.794 96.798  77.101  1.00 149.09 ? 341 GLY B O   1 
ATOM   5820  N  N   . SER B 2 342 ? 105.552 97.101  79.168  1.00 117.48 ? 342 SER B N   1 
ATOM   5821  C  CA  . SER B 2 342 ? 104.875 98.368  79.314  1.00 138.86 ? 342 SER B CA  1 
ATOM   5822  C  C   . SER B 2 342 ? 105.576 99.428  78.472  1.00 111.54 ? 342 SER B C   1 
ATOM   5823  O  O   . SER B 2 342 ? 104.892 100.174 77.809  1.00 150.20 ? 342 SER B O   1 
ATOM   5824  C  CB  . SER B 2 342 ? 104.762 98.754  80.786  1.00 219.36 ? 342 SER B CB  1 
ATOM   5825  O  OG  . SER B 2 342 ? 103.861 99.848  80.965  1.00 183.34 ? 342 SER B OG  1 
ATOM   5826  N  N   . LEU B 2 343 ? 106.912 99.530  78.491  1.00 114.80 ? 343 LEU B N   1 
ATOM   5827  C  CA  . LEU B 2 343 ? 107.629 100.569 77.752  1.00 132.80 ? 343 LEU B CA  1 
ATOM   5828  C  C   . LEU B 2 343 ? 107.386 100.421 76.274  1.00 142.19 ? 343 LEU B C   1 
ATOM   5829  O  O   . LEU B 2 343 ? 107.260 101.434 75.587  1.00 155.36 ? 343 LEU B O   1 
ATOM   5830  C  CB  . LEU B 2 343 ? 109.145 100.478 77.968  1.00 115.78 ? 343 LEU B CB  1 
ATOM   5831  C  CG  . LEU B 2 343 ? 109.584 101.083 79.285  1.00 180.60 ? 343 LEU B CG  1 
ATOM   5832  C  CD1 . LEU B 2 343 ? 111.030 100.705 79.572  1.00 268.84 ? 343 LEU B CD1 1 
ATOM   5833  C  CD2 . LEU B 2 343 ? 109.352 102.599 79.253  1.00 145.95 ? 343 LEU B CD2 1 
ATOM   5834  N  N   . PHE B 2 344 ? 107.380 99.168  75.820  1.00 132.80 ? 344 PHE B N   1 
ATOM   5835  C  CA  . PHE B 2 344 ? 107.155 98.857  74.426  1.00 132.63 ? 344 PHE B CA  1 
ATOM   5836  C  C   . PHE B 2 344 ? 105.788 99.378  74.058  1.00 114.45 ? 344 PHE B C   1 
ATOM   5837  O  O   . PHE B 2 344 ? 105.668 100.294 73.272  1.00 150.22 ? 344 PHE B O   1 
ATOM   5838  C  CB  . PHE B 2 344 ? 107.275 97.351  74.228  1.00 194.99 ? 344 PHE B CB  1 
ATOM   5839  C  CG  . PHE B 2 344 ? 106.959 96.890  72.841  1.00 168.94 ? 344 PHE B CG  1 
ATOM   5840  C  CD1 . PHE B 2 344 ? 107.757 97.273  71.794  1.00 197.37 ? 344 PHE B CD1 1 
ATOM   5841  C  CD2 . PHE B 2 344 ? 105.885 96.075  72.605  1.00 145.00 ? 344 PHE B CD2 1 
ATOM   5842  C  CE1 . PHE B 2 344 ? 107.467 96.835  70.520  1.00 224.63 ? 344 PHE B CE1 1 
ATOM   5843  C  CE2 . PHE B 2 344 ? 105.601 95.643  71.338  1.00 167.78 ? 344 PHE B CE2 1 
ATOM   5844  C  CZ  . PHE B 2 344 ? 106.385 96.025  70.298  1.00 194.91 ? 344 PHE B CZ  1 
ATOM   5845  N  N   . THR B 2 345 ? 104.785 98.789  74.680  1.00 107.00 ? 345 THR B N   1 
ATOM   5846  C  CA  . THR B 2 345 ? 103.410 99.100  74.400  1.00 122.34 ? 345 THR B CA  1 
ATOM   5847  C  C   . THR B 2 345 ? 103.140 100.600 74.538  1.00 100.90 ? 345 THR B C   1 
ATOM   5848  O  O   . THR B 2 345 ? 102.484 101.185 73.703  1.00 113.17 ? 345 THR B O   1 
ATOM   5849  C  CB  . THR B 2 345 ? 102.534 98.277  75.339  1.00 144.14 ? 345 THR B CB  1 
ATOM   5850  O  OG1 . THR B 2 345 ? 102.858 96.894  75.229  1.00 171.08 ? 345 THR B OG1 1 
ATOM   5851  C  CG2 . THR B 2 345 ? 101.070 98.320  75.008  1.00 184.64 ? 345 THR B CG2 1 
ATOM   5852  N  N   . SER B 2 346 ? 103.623 101.216 75.599  1.00 127.97 ? 346 SER B N   1 
ATOM   5853  C  CA  . SER B 2 346 ? 103.392 102.619 75.905  1.00 158.78 ? 346 SER B CA  1 
ATOM   5854  C  C   . SER B 2 346 ? 103.937 103.530 74.813  1.00 132.94 ? 346 SER B C   1 
ATOM   5855  O  O   . SER B 2 346 ? 103.284 104.487 74.442  1.00 122.36 ? 346 SER B O   1 
ATOM   5856  C  CB  . SER B 2 346 ? 103.989 102.924 77.239  1.00 207.86 ? 346 SER B CB  1 
ATOM   5857  O  OG  . SER B 2 346 ? 103.758 104.266 77.632  1.00 241.50 ? 346 SER B OG  1 
ATOM   5858  N  N   . SER B 2 347 ? 105.116 103.229 74.273  1.00 145.23 ? 347 SER B N   1 
ATOM   5859  C  CA  . SER B 2 347 ? 105.675 104.014 73.163  1.00 174.05 ? 347 SER B CA  1 
ATOM   5860  C  C   . SER B 2 347 ? 104.777 104.052 71.925  1.00 149.13 ? 347 SER B C   1 
ATOM   5861  O  O   . SER B 2 347 ? 104.810 105.023 71.188  1.00 150.21 ? 347 SER B O   1 
ATOM   5862  C  CB  . SER B 2 347 ? 107.050 103.535 72.756  1.00 124.20 ? 347 SER B CB  1 
ATOM   5863  O  OG  . SER B 2 347 ? 106.921 102.307 72.068  1.00 154.55 ? 347 SER B OG  1 
ATOM   5864  N  N   . ARG B 2 348 ? 103.993 103.007 71.706  1.00 117.57 ? 348 ARG B N   1 
ATOM   5865  C  CA  . ARG B 2 348 ? 103.112 102.952 70.571  1.00 114.03 ? 348 ARG B CA  1 
ATOM   5866  C  C   . ARG B 2 348 ? 101.877 103.796 70.832  1.00 128.84 ? 348 ARG B C   1 
ATOM   5867  O  O   . ARG B 2 348 ? 101.354 104.339 69.880  1.00 163.30 ? 348 ARG B O   1 
ATOM   5868  C  CB  . ARG B 2 348 ? 102.716 101.495 70.268  1.00 151.74 ? 348 ARG B CB  1 
ATOM   5869  C  CG  . ARG B 2 348 ? 103.893 100.549 70.059  1.00 139.31 ? 348 ARG B CG  1 
ATOM   5870  C  CD  . ARG B 2 348 ? 105.001 101.216 69.261  1.00 134.57 ? 348 ARG B CD  1 
ATOM   5871  N  NE  . ARG B 2 348 ? 105.834 100.197 68.677  1.00 169.19 ? 348 ARG B NE  1 
ATOM   5872  C  CZ  . ARG B 2 348 ? 107.130 100.019 68.873  1.00 163.55 ? 348 ARG B CZ  1 
ATOM   5873  N  NH1 . ARG B 2 348 ? 107.776 99.185  68.088  1.00 198.36 ? 348 ARG B NH1 1 
ATOM   5874  N  NH2 . ARG B 2 348 ? 107.798 100.660 69.806  1.00 143.85 ? 348 ARG B NH2 1 
ATOM   5875  N  N   . LEU B 2 349 ? 101.389 103.901 72.074  1.00 131.69 ? 349 LEU B N   1 
ATOM   5876  C  CA  . LEU B 2 349 ? 100.216 104.689 72.394  1.00 131.23 ? 349 LEU B CA  1 
ATOM   5877  C  C   . LEU B 2 349 ? 100.517 106.145 72.067  1.00 144.21 ? 349 LEU B C   1 
ATOM   5878  O  O   . LEU B 2 349 ? 99.707  106.787 71.402  1.00 186.55 ? 349 LEU B O   1 
ATOM   5879  C  CB  . LEU B 2 349 ? 99.834  104.463 73.857  1.00 155.29 ? 349 LEU B CB  1 
ATOM   5880  C  CG  . LEU B 2 349 ? 98.705  105.326 74.404  1.00 191.17 ? 349 LEU B CG  1 
ATOM   5881  C  CD1 . LEU B 2 349 ? 97.442  105.180 73.549  1.00 207.42 ? 349 LEU B CD1 1 
ATOM   5882  C  CD2 . LEU B 2 349 ? 98.417  104.980 75.883  1.00 258.82 ? 349 LEU B CD2 1 
ATOM   5883  N  N   . PHE B 2 350 ? 101.663 106.680 72.511  1.00 134.90 ? 350 PHE B N   1 
ATOM   5884  C  CA  . PHE B 2 350 ? 101.959 108.090 72.260  1.00 174.09 ? 350 PHE B CA  1 
ATOM   5885  C  C   . PHE B 2 350 ? 102.257 108.334 70.779  1.00 165.08 ? 350 PHE B C   1 
ATOM   5886  O  O   . PHE B 2 350 ? 101.874 109.385 70.243  1.00 121.27 ? 350 PHE B O   1 
ATOM   5887  C  CB  . PHE B 2 350 ? 103.042 108.621 73.205  1.00 180.57 ? 350 PHE B CB  1 
ATOM   5888  C  CG  . PHE B 2 350 ? 102.752 108.364 74.670  1.00 188.39 ? 350 PHE B CG  1 
ATOM   5889  C  CD1 . PHE B 2 350 ? 101.465 108.474 75.216  1.00 155.06 ? 350 PHE B CD1 1 
ATOM   5890  C  CD2 . PHE B 2 350 ? 103.782 107.993 75.518  1.00 235.76 ? 350 PHE B CD2 1 
ATOM   5891  C  CE1 . PHE B 2 350 ? 101.231 108.218 76.560  1.00 167.78 ? 350 PHE B CE1 1 
ATOM   5892  C  CE2 . PHE B 2 350 ? 103.555 107.751 76.866  1.00 239.82 ? 350 PHE B CE2 1 
ATOM   5893  C  CZ  . PHE B 2 350 ? 102.281 107.856 77.382  1.00 210.70 ? 350 PHE B CZ  1 
ATOM   5894  N  N   . PHE B 2 351 ? 102.911 107.372 70.122  1.00 140.04 ? 351 PHE B N   1 
ATOM   5895  C  CA  . PHE B 2 351 ? 103.085 107.395 68.671  1.00 157.19 ? 351 PHE B CA  1 
ATOM   5896  C  C   . PHE B 2 351 ? 101.768 107.588 67.944  1.00 125.85 ? 351 PHE B C   1 
ATOM   5897  O  O   . PHE B 2 351 ? 101.641 108.563 67.203  1.00 149.23 ? 351 PHE B O   1 
ATOM   5898  C  CB  . PHE B 2 351 ? 103.736 106.104 68.208  1.00 178.59 ? 351 PHE B CB  1 
ATOM   5899  C  CG  . PHE B 2 351 ? 103.940 105.906 66.736  1.00 167.17 ? 351 PHE B CG  1 
ATOM   5900  C  CD1 . PHE B 2 351 ? 105.072 106.428 66.110  1.00 191.49 ? 351 PHE B CD1 1 
ATOM   5901  C  CD2 . PHE B 2 351 ? 103.021 105.172 66.016  1.00 157.04 ? 351 PHE B CD2 1 
ATOM   5902  C  CE1 . PHE B 2 351 ? 105.273 106.235 64.759  1.00 191.59 ? 351 PHE B CE1 1 
ATOM   5903  C  CE2 . PHE B 2 351 ? 103.223 104.978 64.661  1.00 267.23 ? 351 PHE B CE2 1 
ATOM   5904  C  CZ  . PHE B 2 351 ? 104.341 105.508 64.039  1.00 284.61 ? 351 PHE B CZ  1 
ATOM   5905  N  N   . VAL B 2 352 ? 100.810 106.699 68.211  1.00 103.72 ? 352 VAL B N   1 
ATOM   5906  C  CA  . VAL B 2 352 ? 99.495  106.817 67.606  1.00 128.13 ? 352 VAL B CA  1 
ATOM   5907  C  C   . VAL B 2 352 ? 98.821  108.144 67.984  1.00 157.00 ? 352 VAL B C   1 
ATOM   5908  O  O   . VAL B 2 352 ? 98.281  108.813 67.089  1.00 261.13 ? 352 VAL B O   1 
ATOM   5909  C  CB  . VAL B 2 352 ? 98.606  105.602 67.909  1.00 138.54 ? 352 VAL B CB  1 
ATOM   5910  C  CG1 . VAL B 2 352 ? 97.192  105.754 67.375  1.00 187.04 ? 352 VAL B CG1 1 
ATOM   5911  C  CG2 . VAL B 2 352 ? 99.230  104.363 67.299  1.00 168.16 ? 352 VAL B CG2 1 
ATOM   5912  N  N   . GLY B 2 353 ? 98.846  108.535 69.262  1.00 109.38 ? 353 GLY B N   1 
ATOM   5913  C  CA  . GLY B 2 353 ? 98.284  109.821 69.648  1.00 149.88 ? 353 GLY B CA  1 
ATOM   5914  C  C   . GLY B 2 353 ? 98.819  111.024 68.839  1.00 181.91 ? 353 GLY B C   1 
ATOM   5915  O  O   . GLY B 2 353 ? 98.066  111.959 68.551  1.00 182.02 ? 353 GLY B O   1 
ATOM   5916  N  N   . SER B 2 354 ? 100.110 111.005 68.470  1.00 186.79 ? 354 SER B N   1 
ATOM   5917  C  CA  . SER B 2 354 ? 100.688 112.076 67.661  1.00 190.91 ? 354 SER B CA  1 
ATOM   5918  C  C   . SER B 2 354 ? 100.306 111.950 66.182  1.00 198.82 ? 354 SER B C   1 
ATOM   5919  O  O   . SER B 2 354 ? 100.141 112.968 65.510  1.00 177.60 ? 354 SER B O   1 
ATOM   5920  C  CB  . SER B 2 354 ? 102.182 112.144 67.832  1.00 174.78 ? 354 SER B CB  1 
ATOM   5921  O  OG  . SER B 2 354 ? 102.825 111.034 67.210  1.00 192.44 ? 354 SER B OG  1 
ATOM   5922  N  N   . ARG B 2 355 ? 100.162 110.715 65.677  1.00 214.43 ? 355 ARG B N   1 
ATOM   5923  C  CA  . ARG B 2 355 ? 99.774  110.474 64.294  1.00 216.09 ? 355 ARG B CA  1 
ATOM   5924  C  C   . ARG B 2 355 ? 98.366  111.014 64.044  1.00 174.92 ? 355 ARG B C   1 
ATOM   5925  O  O   . ARG B 2 355 ? 98.126  111.597 62.979  1.00 182.28 ? 355 ARG B O   1 
ATOM   5926  C  CB  . ARG B 2 355 ? 99.881  108.978 63.979  1.00 238.32 ? 355 ARG B CB  1 
ATOM   5927  C  CG  . ARG B 2 355 ? 99.778  108.654 62.496  1.00 277.30 ? 355 ARG B CG  1 
ATOM   5928  C  CD  . ARG B 2 355 ? 100.107 107.212 62.182  1.00 271.18 ? 355 ARG B CD  1 
ATOM   5929  N  NE  . ARG B 2 355 ? 99.128  106.289 62.763  1.00 258.60 ? 355 ARG B NE  1 
ATOM   5930  C  CZ  . ARG B 2 355 ? 99.212  104.957 62.711  1.00 310.97 ? 355 ARG B CZ  1 
ATOM   5931  N  NH1 . ARG B 2 355 ? 98.323  104.210 63.350  1.00 306.48 ? 355 ARG B NH1 1 
ATOM   5932  N  NH2 . ARG B 2 355 ? 100.191 104.375 62.031  1.00 312.17 ? 355 ARG B NH2 1 
ATOM   5933  N  N   . GLU B 2 356 ? 97.462  110.824 65.026  1.00 181.54 ? 356 GLU B N   1 
ATOM   5934  C  CA  . GLU B 2 356 ? 96.086  111.314 64.956  1.00 231.89 ? 356 GLU B CA  1 
ATOM   5935  C  C   . GLU B 2 356 ? 95.961  112.790 65.363  1.00 231.82 ? 356 GLU B C   1 
ATOM   5936  O  O   . GLU B 2 356 ? 94.839  113.290 65.483  1.00 212.52 ? 356 GLU B O   1 
ATOM   5937  C  CB  . GLU B 2 356 ? 95.174  110.450 65.833  1.00 249.14 ? 356 GLU B CB  1 
ATOM   5938  C  CG  . GLU B 2 356 ? 95.170  108.961 65.464  1.00 301.50 ? 356 GLU B CG  1 
ATOM   5939  C  CD  . GLU B 2 356 ? 94.766  108.551 64.059  1.00 286.04 ? 356 GLU B CD  1 
ATOM   5940  O  OE1 . GLU B 2 356 ? 94.158  109.383 63.352  1.00 298.66 ? 356 GLU B OE1 1 
ATOM   5941  O  OE2 . GLU B 2 356 ? 95.091  107.399 63.674  1.00 284.58 ? 356 GLU B OE2 1 
ATOM   5942  N  N   . GLY B 2 357 ? 97.087  113.494 65.577  1.00 214.01 ? 357 GLY B N   1 
ATOM   5943  C  CA  . GLY B 2 357 ? 97.102  114.947 65.670  1.00 246.73 ? 357 GLY B CA  1 
ATOM   5944  C  C   . GLY B 2 357 ? 96.807  115.477 67.068  1.00 247.97 ? 357 GLY B C   1 
ATOM   5945  O  O   . GLY B 2 357 ? 96.851  116.693 67.267  1.00 260.89 ? 357 GLY B O   1 
ATOM   5946  N  N   . HIS B 2 358 ? 96.523  114.574 68.023  1.00 251.75 ? 358 HIS B N   1 
ATOM   5947  C  CA  . HIS B 2 358 ? 96.253  114.932 69.411  1.00 270.32 ? 358 HIS B CA  1 
ATOM   5948  C  C   . HIS B 2 358 ? 97.507  115.412 70.146  1.00 244.80 ? 358 HIS B C   1 
ATOM   5949  O  O   . HIS B 2 358 ? 97.377  116.059 71.190  1.00 223.57 ? 358 HIS B O   1 
ATOM   5950  C  CB  . HIS B 2 358 ? 95.648  113.734 70.149  1.00 245.51 ? 358 HIS B CB  1 
ATOM   5951  C  CG  . HIS B 2 358 ? 94.211  113.523 69.848  1.00 245.03 ? 358 HIS B CG  1 
ATOM   5952  N  ND1 . HIS B 2 358 ? 93.605  113.736 68.630  1.00 211.43 ? 358 HIS B ND1 1 
ATOM   5953  C  CD2 . HIS B 2 358 ? 93.255  113.105 70.674  1.00 241.59 ? 358 HIS B CD2 1 
ATOM   5954  C  CE1 . HIS B 2 358 ? 92.321  113.452 68.734  1.00 231.27 ? 358 HIS B CE1 1 
ATOM   5955  N  NE2 . HIS B 2 358 ? 92.084  113.068 69.969  1.00 246.03 ? 358 HIS B NE2 1 
ATOM   5956  N  N   . LEU B 2 359 ? 98.702  115.096 69.617  1.00 198.00 ? 359 LEU B N   1 
ATOM   5957  C  CA  . LEU B 2 359 ? 99.921  115.216 70.389  1.00 185.74 ? 359 LEU B CA  1 
ATOM   5958  C  C   . LEU B 2 359 ? 101.061 115.707 69.483  1.00 197.74 ? 359 LEU B C   1 
ATOM   5959  O  O   . LEU B 2 359 ? 101.085 115.363 68.308  1.00 222.24 ? 359 LEU B O   1 
ATOM   5960  C  CB  . LEU B 2 359 ? 100.114 113.812 70.989  1.00 165.14 ? 359 LEU B CB  1 
ATOM   5961  C  CG  . LEU B 2 359 ? 100.976 113.665 72.238  1.00 240.61 ? 359 LEU B CG  1 
ATOM   5962  C  CD1 . LEU B 2 359 ? 100.352 114.315 73.474  1.00 309.76 ? 359 LEU B CD1 1 
ATOM   5963  C  CD2 . LEU B 2 359 ? 101.215 112.182 72.520  1.00 185.01 ? 359 LEU B CD2 1 
ATOM   5964  N  N   . PRO B 2 360 ? 102.037 116.518 69.991  1.00 228.11 ? 360 PRO B N   1 
ATOM   5965  C  CA  . PRO B 2 360 ? 103.118 117.103 69.178  1.00 201.60 ? 360 PRO B CA  1 
ATOM   5966  C  C   . PRO B 2 360 ? 103.881 116.145 68.246  1.00 182.16 ? 360 PRO B C   1 
ATOM   5967  O  O   . PRO B 2 360 ? 104.283 115.039 68.620  1.00 182.37 ? 360 PRO B O   1 
ATOM   5968  C  CB  . PRO B 2 360 ? 104.121 117.673 70.211  1.00 259.29 ? 360 PRO B CB  1 
ATOM   5969  C  CG  . PRO B 2 360 ? 103.674 117.126 71.555  1.00 285.58 ? 360 PRO B CG  1 
ATOM   5970  C  CD  . PRO B 2 360 ? 102.180 116.934 71.398  1.00 278.42 ? 360 PRO B CD  1 
ATOM   5971  N  N   . SER B 2 361 ? 104.080 116.615 67.010  1.00 213.42 ? 361 SER B N   1 
ATOM   5972  C  CA  . SER B 2 361 ? 104.360 115.792 65.840  1.00 230.01 ? 361 SER B CA  1 
ATOM   5973  C  C   . SER B 2 361 ? 105.679 115.028 65.942  1.00 190.49 ? 361 SER B C   1 
ATOM   5974  O  O   . SER B 2 361 ? 105.848 114.049 65.207  1.00 157.46 ? 361 SER B O   1 
ATOM   5975  C  CB  . SER B 2 361 ? 104.336 116.648 64.593  1.00 266.87 ? 361 SER B CB  1 
ATOM   5976  O  OG  . SER B 2 361 ? 104.409 115.852 63.423  1.00 303.22 ? 361 SER B OG  1 
ATOM   5977  N  N   . ILE B 2 362 ? 106.595 115.458 66.830  1.00 146.51 ? 362 ILE B N   1 
ATOM   5978  C  CA  . ILE B 2 362 ? 107.885 114.781 66.950  1.00 186.79 ? 362 ILE B CA  1 
ATOM   5979  C  C   . ILE B 2 362 ? 107.688 113.301 67.311  1.00 207.92 ? 362 ILE B C   1 
ATOM   5980  O  O   . ILE B 2 362 ? 108.429 112.438 66.841  1.00 157.14 ? 362 ILE B O   1 
ATOM   5981  C  CB  . ILE B 2 362 ? 108.854 115.439 67.960  1.00 219.24 ? 362 ILE B CB  1 
ATOM   5982  C  CG1 . ILE B 2 362 ? 108.754 116.974 68.020  1.00 290.36 ? 362 ILE B CG1 1 
ATOM   5983  C  CG2 . ILE B 2 362 ? 110.283 114.930 67.668  1.00 185.52 ? 362 ILE B CG2 1 
ATOM   5984  C  CD1 . ILE B 2 362 ? 109.613 117.646 69.078  1.00 352.84 ? 362 ILE B CD1 1 
ATOM   5985  N  N   . LEU B 2 363 ? 106.685 112.998 68.146  1.00 229.69 ? 363 LEU B N   1 
ATOM   5986  C  CA  . LEU B 2 363 ? 106.455 111.637 68.625  1.00 210.98 ? 363 LEU B CA  1 
ATOM   5987  C  C   . LEU B 2 363 ? 106.022 110.655 67.519  1.00 213.33 ? 363 LEU B C   1 
ATOM   5988  O  O   . LEU B 2 363 ? 106.011 109.445 67.766  1.00 220.06 ? 363 LEU B O   1 
ATOM   5989  C  CB  . LEU B 2 363 ? 105.407 111.699 69.747  1.00 176.55 ? 363 LEU B CB  1 
ATOM   5990  C  CG  . LEU B 2 363 ? 105.929 111.966 71.154  1.00 163.48 ? 363 LEU B CG  1 
ATOM   5991  C  CD1 . LEU B 2 363 ? 106.919 113.110 71.205  1.00 204.20 ? 363 LEU B CD1 1 
ATOM   5992  C  CD2 . LEU B 2 363 ? 104.776 112.260 72.098  1.00 155.57 ? 363 LEU B CD2 1 
ATOM   5993  N  N   . SER B 2 364 ? 105.658 111.143 66.315  1.00 161.63 ? 364 SER B N   1 
ATOM   5994  C  CA  . SER B 2 364 ? 105.340 110.273 65.192  1.00 202.72 ? 364 SER B CA  1 
ATOM   5995  C  C   . SER B 2 364 ? 106.588 109.818 64.425  1.00 205.77 ? 364 SER B C   1 
ATOM   5996  O  O   . SER B 2 364 ? 106.501 108.898 63.617  1.00 151.78 ? 364 SER B O   1 
ATOM   5997  C  CB  . SER B 2 364 ? 104.375 110.956 64.252  1.00 263.00 ? 364 SER B CB  1 
ATOM   5998  O  OG  . SER B 2 364 ? 105.006 112.033 63.576  1.00 285.40 ? 364 SER B OG  1 
ATOM   5999  N  N   . MET B 2 365 ? 107.745 110.451 64.654  1.00 207.98 ? 365 MET B N   1 
ATOM   6000  C  CA  . MET B 2 365 ? 108.919 110.239 63.813  1.00 195.20 ? 365 MET B CA  1 
ATOM   6001  C  C   . MET B 2 365 ? 109.561 108.881 64.124  1.00 113.75 ? 365 MET B C   1 
ATOM   6002  O  O   . MET B 2 365 ? 109.488 108.414 65.236  1.00 165.32 ? 365 MET B O   1 
ATOM   6003  C  CB  . MET B 2 365 ? 109.960 111.355 64.009  1.00 199.98 ? 365 MET B CB  1 
ATOM   6004  C  CG  . MET B 2 365 ? 109.416 112.789 63.886  1.00 204.09 ? 365 MET B CG  1 
ATOM   6005  S  SD  . MET B 2 365 ? 109.179 113.403 62.217  1.00 210.16 ? 365 MET B SD  1 
ATOM   6006  C  CE  . MET B 2 365 ? 108.667 115.080 62.579  1.00 255.41 ? 365 MET B CE  1 
ATOM   6007  N  N   . ILE B 2 366 ? 110.176 108.261 63.137  1.00 94.55  ? 366 ILE B N   1 
ATOM   6008  C  CA  . ILE B 2 366 ? 110.821 106.962 63.233  1.00 141.25 ? 366 ILE B CA  1 
ATOM   6009  C  C   . ILE B 2 366 ? 112.295 107.110 62.839  1.00 173.23 ? 366 ILE B C   1 
ATOM   6010  O  O   . ILE B 2 366 ? 112.618 108.008 62.073  1.00 183.36 ? 366 ILE B O   1 
ATOM   6011  C  CB  . ILE B 2 366 ? 110.083 105.987 62.290  1.00 161.01 ? 366 ILE B CB  1 
ATOM   6012  C  CG1 . ILE B 2 366 ? 108.609 105.822 62.677  1.00 148.26 ? 366 ILE B CG1 1 
ATOM   6013  C  CG2 . ILE B 2 366 ? 110.839 104.657 62.162  1.00 142.63 ? 366 ILE B CG2 1 
ATOM   6014  C  CD1 . ILE B 2 366 ? 107.820 104.937 61.700  1.00 258.23 ? 366 ILE B CD1 1 
ATOM   6015  N  N   . HIS B 2 367 ? 113.192 106.227 63.317  1.00 163.70 ? 367 HIS B N   1 
ATOM   6016  C  CA  . HIS B 2 367 ? 114.590 106.243 62.899  1.00 199.38 ? 367 HIS B CA  1 
ATOM   6017  C  C   . HIS B 2 367 ? 114.764 105.354 61.673  1.00 244.37 ? 367 HIS B C   1 
ATOM   6018  O  O   . HIS B 2 367 ? 114.667 104.142 61.825  1.00 175.24 ? 367 HIS B O   1 
ATOM   6019  C  CB  . HIS B 2 367 ? 115.507 105.781 64.027  1.00 213.56 ? 367 HIS B CB  1 
ATOM   6020  C  CG  . HIS B 2 367 ? 116.966 105.882 63.714  1.00 223.97 ? 367 HIS B CG  1 
ATOM   6021  N  ND1 . HIS B 2 367 ? 117.651 107.049 63.446  1.00 271.30 ? 367 HIS B ND1 1 
ATOM   6022  C  CD2 . HIS B 2 367 ? 117.863 104.912 63.648  1.00 217.06 ? 367 HIS B CD2 1 
ATOM   6023  C  CE1 . HIS B 2 367 ? 118.929 106.759 63.218  1.00 334.85 ? 367 HIS B CE1 1 
ATOM   6024  N  NE2 . HIS B 2 367 ? 119.075 105.463 63.341  1.00 297.85 ? 367 HIS B NE2 1 
ATOM   6025  N  N   . PRO B 2 368 ? 115.019 105.900 60.452  1.00 276.59 ? 368 PRO B N   1 
ATOM   6026  C  CA  . PRO B 2 368 ? 114.980 105.109 59.216  1.00 291.64 ? 368 PRO B CA  1 
ATOM   6027  C  C   . PRO B 2 368 ? 115.773 103.805 59.095  1.00 265.67 ? 368 PRO B C   1 
ATOM   6028  O  O   . PRO B 2 368 ? 115.299 102.907 58.403  1.00 257.39 ? 368 PRO B O   1 
ATOM   6029  C  CB  . PRO B 2 368 ? 115.561 106.076 58.184  1.00 286.86 ? 368 PRO B CB  1 
ATOM   6030  C  CG  . PRO B 2 368 ? 115.071 107.391 58.693  1.00 222.45 ? 368 PRO B CG  1 
ATOM   6031  C  CD  . PRO B 2 368 ? 115.335 107.314 60.171  1.00 216.23 ? 368 PRO B CD  1 
ATOM   6032  N  N   . GLN B 2 369 ? 116.939 103.685 59.744  1.00 239.15 ? 369 GLN B N   1 
ATOM   6033  C  CA  . GLN B 2 369 ? 117.734 102.465 59.597  1.00 311.50 ? 369 GLN B CA  1 
ATOM   6034  C  C   . GLN B 2 369 ? 117.371 101.392 60.643  1.00 324.41 ? 369 GLN B C   1 
ATOM   6035  O  O   . GLN B 2 369 ? 117.783 100.242 60.463  1.00 335.34 ? 369 GLN B O   1 
ATOM   6036  C  CB  . GLN B 2 369 ? 119.240 102.763 59.590  1.00 384.36 ? 369 GLN B CB  1 
ATOM   6037  C  CG  . GLN B 2 369 ? 119.762 103.517 60.806  1.00 432.61 ? 369 GLN B CG  1 
ATOM   6038  C  CD  . GLN B 2 369 ? 121.247 103.390 61.063  1.00 454.65 ? 369 GLN B CD  1 
ATOM   6039  O  OE1 . GLN B 2 369 ? 121.977 102.672 60.381  1.00 410.11 ? 369 GLN B OE1 1 
ATOM   6040  N  NE2 . GLN B 2 369 ? 121.709 104.106 62.077  1.00 460.44 ? 369 GLN B NE2 1 
ATOM   6041  N  N   . LEU B 2 370 ? 116.623 101.731 61.719  1.00 279.14 ? 370 LEU B N   1 
ATOM   6042  C  CA  . LEU B 2 370 ? 116.241 100.774 62.768  1.00 222.22 ? 370 LEU B CA  1 
ATOM   6043  C  C   . LEU B 2 370 ? 114.727 100.548 62.904  1.00 224.41 ? 370 LEU B C   1 
ATOM   6044  O  O   . LEU B 2 370 ? 114.331 99.513  63.453  1.00 163.66 ? 370 LEU B O   1 
ATOM   6045  C  CB  . LEU B 2 370 ? 116.799 101.279 64.096  1.00 168.97 ? 370 LEU B CB  1 
ATOM   6046  C  CG  . LEU B 2 370 ? 118.319 101.312 64.207  1.00 266.04 ? 370 LEU B CG  1 
ATOM   6047  C  CD1 . LEU B 2 370 ? 118.719 101.819 65.586  1.00 356.43 ? 370 LEU B CD1 1 
ATOM   6048  C  CD2 . LEU B 2 370 ? 118.942 99.942  63.943  1.00 314.59 ? 370 LEU B CD2 1 
ATOM   6049  N  N   . LEU B 2 371 ? 113.906 101.508 62.425  1.00 206.02 ? 371 LEU B N   1 
ATOM   6050  C  CA  . LEU B 2 371 ? 112.455 101.414 62.319  1.00 175.27 ? 371 LEU B CA  1 
ATOM   6051  C  C   . LEU B 2 371 ? 111.827 101.263 63.713  1.00 203.65 ? 371 LEU B C   1 
ATOM   6052  O  O   . LEU B 2 371 ? 110.875 100.493 63.887  1.00 279.27 ? 371 LEU B O   1 
ATOM   6053  C  CB  . LEU B 2 371 ? 112.078 100.275 61.348  1.00 251.52 ? 371 LEU B CB  1 
ATOM   6054  C  CG  . LEU B 2 371 ? 112.687 100.334 59.938  1.00 319.38 ? 371 LEU B CG  1 
ATOM   6055  C  CD1 . LEU B 2 371 ? 112.195 99.168  59.093  1.00 332.33 ? 371 LEU B CD1 1 
ATOM   6056  C  CD2 . LEU B 2 371 ? 112.390 101.660 59.251  1.00 382.81 ? 371 LEU B CD2 1 
ATOM   6057  N  N   . THR B 2 372 ? 112.363 102.023 64.696  1.00 201.88 ? 372 THR B N   1 
ATOM   6058  C  CA  . THR B 2 372 ? 111.806 102.151 66.047  1.00 167.63 ? 372 THR B CA  1 
ATOM   6059  C  C   . THR B 2 372 ? 111.476 103.608 66.338  1.00 113.27 ? 372 THR B C   1 
ATOM   6060  O  O   . THR B 2 372 ? 112.138 104.486 65.818  1.00 147.29 ? 372 THR B O   1 
ATOM   6061  C  CB  . THR B 2 372 ? 112.756 101.623 67.118  1.00 184.26 ? 372 THR B CB  1 
ATOM   6062  O  OG1 . THR B 2 372 ? 113.943 102.409 67.069  1.00 191.34 ? 372 THR B OG1 1 
ATOM   6063  C  CG2 . THR B 2 372 ? 113.121 100.156 66.931  1.00 152.25 ? 372 THR B CG2 1 
ATOM   6064  N  N   . PRO B 2 373 ? 110.378 103.927 67.044  1.00 129.40 ? 373 PRO B N   1 
ATOM   6065  C  CA  . PRO B 2 373 ? 109.895 105.303 67.164  1.00 151.43 ? 373 PRO B CA  1 
ATOM   6066  C  C   . PRO B 2 373 ? 110.610 106.094 68.247  1.00 125.43 ? 373 PRO B C   1 
ATOM   6067  O  O   . PRO B 2 373 ? 109.941 106.554 69.168  1.00 106.47 ? 373 PRO B O   1 
ATOM   6068  C  CB  . PRO B 2 373 ? 108.367 105.115 67.362  1.00 148.31 ? 373 PRO B CB  1 
ATOM   6069  C  CG  . PRO B 2 373 ? 108.299 103.830 68.140  1.00 157.27 ? 373 PRO B CG  1 
ATOM   6070  C  CD  . PRO B 2 373 ? 109.457 102.980 67.657  1.00 155.53 ? 373 PRO B CD  1 
ATOM   6071  N  N   . VAL B 2 374 ? 111.930 106.284 68.023  1.00 93.13  ? 374 VAL B N   1 
ATOM   6072  C  CA  . VAL B 2 374 ? 112.877 106.791 69.007  1.00 118.11 ? 374 VAL B CA  1 
ATOM   6073  C  C   . VAL B 2 374 ? 112.424 108.023 69.794  1.00 110.25 ? 374 VAL B C   1 
ATOM   6074  O  O   . VAL B 2 374 ? 112.516 107.957 71.016  1.00 199.99 ? 374 VAL B O   1 
ATOM   6075  C  CB  . VAL B 2 374 ? 114.232 107.006 68.368  1.00 123.09 ? 374 VAL B CB  1 
ATOM   6076  C  CG1 . VAL B 2 374 ? 115.214 107.753 69.263  1.00 140.47 ? 374 VAL B CG1 1 
ATOM   6077  C  CG2 . VAL B 2 374 ? 114.769 105.628 67.964  1.00 153.70 ? 374 VAL B CG2 1 
ATOM   6078  N  N   . PRO B 2 375 ? 111.867 109.106 69.260  1.00 106.90 ? 375 PRO B N   1 
ATOM   6079  C  CA  . PRO B 2 375 ? 111.344 110.179 70.119  1.00 172.96 ? 375 PRO B CA  1 
ATOM   6080  C  C   . PRO B 2 375 ? 110.209 109.792 71.073  1.00 192.66 ? 375 PRO B C   1 
ATOM   6081  O  O   . PRO B 2 375 ? 110.187 110.323 72.185  1.00 221.97 ? 375 PRO B O   1 
ATOM   6082  C  CB  . PRO B 2 375 ? 110.816 111.225 69.128  1.00 232.02 ? 375 PRO B CB  1 
ATOM   6083  C  CG  . PRO B 2 375 ? 111.598 110.898 67.884  1.00 257.28 ? 375 PRO B CG  1 
ATOM   6084  C  CD  . PRO B 2 375 ? 111.654 109.375 67.853  1.00 167.93 ? 375 PRO B CD  1 
ATOM   6085  N  N   . SER B 2 376 ? 109.289 108.889 70.670  1.00 152.97 ? 376 SER B N   1 
ATOM   6086  C  CA  . SER B 2 376 ? 108.267 108.410 71.596  1.00 172.46 ? 376 SER B CA  1 
ATOM   6087  C  C   . SER B 2 376 ? 108.842 107.585 72.760  1.00 167.12 ? 376 SER B C   1 
ATOM   6088  O  O   . SER B 2 376 ? 108.436 107.739 73.912  1.00 159.52 ? 376 SER B O   1 
ATOM   6089  C  CB  . SER B 2 376 ? 107.264 107.612 70.873  1.00 196.98 ? 376 SER B CB  1 
ATOM   6090  O  OG  . SER B 2 376 ? 106.315 107.077 71.789  1.00 223.61 ? 376 SER B OG  1 
ATOM   6091  N  N   . LEU B 2 377 ? 109.779 106.681 72.462  1.00 114.02 ? 377 LEU B N   1 
ATOM   6092  C  CA  . LEU B 2 377 ? 110.507 105.966 73.500  1.00 130.32 ? 377 LEU B CA  1 
ATOM   6093  C  C   . LEU B 2 377 ? 111.246 106.879 74.487  1.00 128.40 ? 377 LEU B C   1 
ATOM   6094  O  O   . LEU B 2 377 ? 111.110 106.750 75.715  1.00 137.84 ? 377 LEU B O   1 
ATOM   6095  C  CB  . LEU B 2 377 ? 111.482 105.020 72.816  1.00 108.50 ? 377 LEU B CB  1 
ATOM   6096  C  CG  . LEU B 2 377 ? 110.808 103.775 72.267  1.00 124.69 ? 377 LEU B CG  1 
ATOM   6097  C  CD1 . LEU B 2 377 ? 111.768 103.055 71.368  1.00 183.03 ? 377 LEU B CD1 1 
ATOM   6098  C  CD2 . LEU B 2 377 ? 110.395 102.818 73.378  1.00 166.26 ? 377 LEU B CD2 1 
ATOM   6099  N  N   . VAL B 2 378 ? 112.017 107.804 73.935  1.00 139.69 ? 378 VAL B N   1 
ATOM   6100  C  CA  . VAL B 2 378 ? 112.781 108.718 74.758  1.00 153.38 ? 378 VAL B CA  1 
ATOM   6101  C  C   . VAL B 2 378 ? 111.824 109.517 75.631  1.00 125.07 ? 378 VAL B C   1 
ATOM   6102  O  O   . VAL B 2 378 ? 112.140 109.726 76.800  1.00 195.97 ? 378 VAL B O   1 
ATOM   6103  C  CB  . VAL B 2 378 ? 113.679 109.602 73.891  1.00 236.43 ? 378 VAL B CB  1 
ATOM   6104  C  CG1 . VAL B 2 378 ? 114.211 110.829 74.624  1.00 318.77 ? 378 VAL B CG1 1 
ATOM   6105  C  CG2 . VAL B 2 378 ? 114.816 108.756 73.339  1.00 301.75 ? 378 VAL B CG2 1 
ATOM   6106  N  N   . PHE B 2 379 ? 110.677 109.929 75.096  1.00 106.76 ? 379 PHE B N   1 
ATOM   6107  C  CA  . PHE B 2 379 ? 109.705 110.660 75.902  1.00 167.60 ? 379 PHE B CA  1 
ATOM   6108  C  C   . PHE B 2 379 ? 109.172 109.799 77.046  1.00 152.95 ? 379 PHE B C   1 
ATOM   6109  O  O   . PHE B 2 379 ? 109.074 110.257 78.194  1.00 141.08 ? 379 PHE B O   1 
ATOM   6110  C  CB  . PHE B 2 379 ? 108.574 111.176 75.014  1.00 198.25 ? 379 PHE B CB  1 
ATOM   6111  C  CG  . PHE B 2 379 ? 107.423 111.781 75.763  1.00 195.37 ? 379 PHE B CG  1 
ATOM   6112  C  CD1 . PHE B 2 379 ? 107.554 113.020 76.376  1.00 195.95 ? 379 PHE B CD1 1 
ATOM   6113  C  CD2 . PHE B 2 379 ? 106.213 111.109 75.854  1.00 181.47 ? 379 PHE B CD2 1 
ATOM   6114  C  CE1 . PHE B 2 379 ? 106.483 113.577 77.059  1.00 251.63 ? 379 PHE B CE1 1 
ATOM   6115  C  CE2 . PHE B 2 379 ? 105.141 111.669 76.543  1.00 207.80 ? 379 PHE B CE2 1 
ATOM   6116  C  CZ  . PHE B 2 379 ? 105.281 112.898 77.149  1.00 245.93 ? 379 PHE B CZ  1 
ATOM   6117  N  N   . THR B 2 380 ? 108.838 108.546 76.730  1.00 135.84 ? 380 THR B N   1 
ATOM   6118  C  CA  . THR B 2 380 ? 108.309 107.603 77.714  1.00 171.78 ? 380 THR B CA  1 
ATOM   6119  C  C   . THR B 2 380 ? 109.288 107.290 78.852  1.00 137.40 ? 380 THR B C   1 
ATOM   6120  O  O   . THR B 2 380 ? 108.857 107.233 80.008  1.00 150.62 ? 380 THR B O   1 
ATOM   6121  C  CB  . THR B 2 380 ? 107.859 106.324 77.009  1.00 210.05 ? 380 THR B CB  1 
ATOM   6122  O  OG1 . THR B 2 380 ? 106.883 106.710 76.035  1.00 328.22 ? 380 THR B OG1 1 
ATOM   6123  C  CG2 . THR B 2 380 ? 107.231 105.308 77.936  1.00 213.25 ? 380 THR B CG2 1 
ATOM   6124  N  N   . CYS B 2 381 ? 110.565 107.081 78.525  1.00 107.86 ? 381 CYS B N   1 
ATOM   6125  C  CA  . CYS B 2 381 ? 111.569 106.961 79.561  1.00 115.97 ? 381 CYS B CA  1 
ATOM   6126  C  C   . CYS B 2 381 ? 111.614 108.207 80.463  1.00 124.01 ? 381 CYS B C   1 
ATOM   6127  O  O   . CYS B 2 381 ? 111.499 108.093 81.671  1.00 133.95 ? 381 CYS B O   1 
ATOM   6128  C  CB  . CYS B 2 381 ? 112.966 106.807 78.979  1.00 196.66 ? 381 CYS B CB  1 
ATOM   6129  S  SG  . CYS B 2 381 ? 114.257 106.635 80.258  1.00 162.29 ? 381 CYS B SG  1 
ATOM   6130  N  N   . VAL B 2 382 ? 111.809 109.396 79.890  1.00 124.39 ? 382 VAL B N   1 
ATOM   6131  C  CA  . VAL B 2 382 ? 111.913 110.619 80.671  1.00 147.12 ? 382 VAL B CA  1 
ATOM   6132  C  C   . VAL B 2 382 ? 110.673 110.784 81.555  1.00 145.05 ? 382 VAL B C   1 
ATOM   6133  O  O   . VAL B 2 382 ? 110.829 111.031 82.762  1.00 164.40 ? 382 VAL B O   1 
ATOM   6134  C  CB  . VAL B 2 382 ? 112.172 111.826 79.755  1.00 238.73 ? 382 VAL B CB  1 
ATOM   6135  C  CG1 . VAL B 2 382 ? 111.945 113.184 80.426  1.00 305.60 ? 382 VAL B CG1 1 
ATOM   6136  C  CG2 . VAL B 2 382 ? 113.583 111.723 79.182  1.00 289.73 ? 382 VAL B CG2 1 
ATOM   6137  N  N   . MET B 2 383 ? 109.471 110.616 80.983  1.00 104.18 ? 383 MET B N   1 
ATOM   6138  C  CA  . MET B 2 383 ? 108.278 110.745 81.795  1.00 132.56 ? 383 MET B CA  1 
ATOM   6139  C  C   . MET B 2 383 ? 108.208 109.702 82.921  1.00 146.83 ? 383 MET B C   1 
ATOM   6140  O  O   . MET B 2 383 ? 107.536 109.944 83.921  1.00 129.78 ? 383 MET B O   1 
ATOM   6141  C  CB  . MET B 2 383 ? 107.026 110.598 80.927  1.00 179.76 ? 383 MET B CB  1 
ATOM   6142  C  CG  . MET B 2 383 ? 106.697 111.829 80.158  1.00 203.06 ? 383 MET B CG  1 
ATOM   6143  S  SD  . MET B 2 383 ? 106.496 113.301 81.171  1.00 265.31 ? 383 MET B SD  1 
ATOM   6144  C  CE  . MET B 2 383 ? 105.130 112.868 82.237  1.00 294.00 ? 383 MET B CE  1 
ATOM   6145  N  N   . THR B 2 384 ? 108.853 108.538 82.778  1.00 138.48 ? 384 THR B N   1 
ATOM   6146  C  CA  . THR B 2 384 ? 108.921 107.572 83.863  1.00 136.55 ? 384 THR B CA  1 
ATOM   6147  C  C   . THR B 2 384 ? 109.861 108.054 84.955  1.00 117.40 ? 384 THR B C   1 
ATOM   6148  O  O   . THR B 2 384 ? 109.567 107.926 86.132  1.00 119.06 ? 384 THR B O   1 
ATOM   6149  C  CB  . THR B 2 384 ? 109.406 106.188 83.409  1.00 146.34 ? 384 THR B CB  1 
ATOM   6150  O  OG1 . THR B 2 384 ? 108.429 105.853 82.427  1.00 145.39 ? 384 THR B OG1 1 
ATOM   6151  C  CG2 . THR B 2 384 ? 109.517 105.122 84.484  1.00 147.75 ? 384 THR B CG2 1 
ATOM   6152  N  N   . LEU B 2 385 ? 111.019 108.556 84.560  1.00 110.00 ? 385 LEU B N   1 
ATOM   6153  C  CA  . LEU B 2 385 ? 112.012 108.881 85.557  1.00 119.82 ? 385 LEU B CA  1 
ATOM   6154  C  C   . LEU B 2 385 ? 111.559 110.108 86.337  1.00 135.07 ? 385 LEU B C   1 
ATOM   6155  O  O   . LEU B 2 385 ? 111.951 110.244 87.479  1.00 132.99 ? 385 LEU B O   1 
ATOM   6156  C  CB  . LEU B 2 385 ? 113.343 109.041 84.835  1.00 133.07 ? 385 LEU B CB  1 
ATOM   6157  C  CG  . LEU B 2 385 ? 113.870 107.709 84.285  1.00 159.53 ? 385 LEU B CG  1 
ATOM   6158  C  CD1 . LEU B 2 385 ? 115.117 107.937 83.487  1.00 208.51 ? 385 LEU B CD1 1 
ATOM   6159  C  CD2 . LEU B 2 385 ? 114.132 106.724 85.413  1.00 144.14 ? 385 LEU B CD2 1 
ATOM   6160  N  N   . LEU B 2 386 ? 110.725 110.985 85.773  1.00 137.28 ? 386 LEU B N   1 
ATOM   6161  C  CA  . LEU B 2 386 ? 110.207 112.109 86.544  1.00 176.18 ? 386 LEU B CA  1 
ATOM   6162  C  C   . LEU B 2 386 ? 109.336 111.679 87.734  1.00 161.96 ? 386 LEU B C   1 
ATOM   6163  O  O   . LEU B 2 386 ? 109.015 112.517 88.571  1.00 177.39 ? 386 LEU B O   1 
ATOM   6164  C  CB  . LEU B 2 386 ? 109.453 113.054 85.600  1.00 196.31 ? 386 LEU B CB  1 
ATOM   6165  C  CG  . LEU B 2 386 ? 110.323 113.767 84.565  1.00 288.06 ? 386 LEU B CG  1 
ATOM   6166  C  CD1 . LEU B 2 386 ? 109.463 114.569 83.613  1.00 361.02 ? 386 LEU B CD1 1 
ATOM   6167  C  CD2 . LEU B 2 386 ? 111.365 114.680 85.206  1.00 385.08 ? 386 LEU B CD2 1 
ATOM   6168  N  N   . TYR B 2 387 ? 108.926 110.401 87.822  1.00 161.68 ? 387 TYR B N   1 
ATOM   6169  C  CA  . TYR B 2 387 ? 108.236 109.868 89.003  1.00 153.99 ? 387 TYR B CA  1 
ATOM   6170  C  C   . TYR B 2 387 ? 109.233 109.421 90.068  1.00 136.88 ? 387 TYR B C   1 
ATOM   6171  O  O   . TYR B 2 387 ? 108.836 109.309 91.223  1.00 179.18 ? 387 TYR B O   1 
ATOM   6172  C  CB  . TYR B 2 387 ? 107.189 108.793 88.637  1.00 162.68 ? 387 TYR B CB  1 
ATOM   6173  C  CG  . TYR B 2 387 ? 105.932 109.526 88.190  1.00 141.17 ? 387 TYR B CG  1 
ATOM   6174  C  CD1 . TYR B 2 387 ? 105.838 110.019 86.903  1.00 170.13 ? 387 TYR B CD1 1 
ATOM   6175  C  CD2 . TYR B 2 387 ? 104.897 109.800 89.050  1.00 159.28 ? 387 TYR B CD2 1 
ATOM   6176  C  CE1 . TYR B 2 387 ? 104.726 110.728 86.475  1.00 205.98 ? 387 TYR B CE1 1 
ATOM   6177  C  CE2 . TYR B 2 387 ? 103.776 110.501 88.633  1.00 247.47 ? 387 TYR B CE2 1 
ATOM   6178  C  CZ  . TYR B 2 387 ? 103.680 110.979 87.335  1.00 213.35 ? 387 TYR B CZ  1 
ATOM   6179  O  OH  . TYR B 2 387 ? 102.560 111.668 86.942  1.00 210.63 ? 387 TYR B OH  1 
ATOM   6180  N  N   . ALA B 2 388 ? 110.514 109.210 89.725  1.00 119.50 ? 388 ALA B N   1 
ATOM   6181  C  CA  . ALA B 2 388 ? 111.543 108.884 90.720  1.00 148.45 ? 388 ALA B CA  1 
ATOM   6182  C  C   . ALA B 2 388 ? 111.742 109.961 91.813  1.00 213.04 ? 388 ALA B C   1 
ATOM   6183  O  O   . ALA B 2 388 ? 112.271 109.677 92.878  1.00 153.37 ? 388 ALA B O   1 
ATOM   6184  C  CB  . ALA B 2 388 ? 112.835 108.600 90.005  1.00 127.22 ? 388 ALA B CB  1 
ATOM   6185  N  N   . PHE B 2 389 ? 111.324 111.210 91.583  1.00 255.05 ? 389 PHE B N   1 
ATOM   6186  C  CA  . PHE B 2 389 ? 111.429 112.273 92.575  1.00 267.45 ? 389 PHE B CA  1 
ATOM   6187  C  C   . PHE B 2 389 ? 110.436 112.140 93.738  1.00 251.96 ? 389 PHE B C   1 
ATOM   6188  O  O   . PHE B 2 389 ? 110.699 112.670 94.823  1.00 264.38 ? 389 PHE B O   1 
ATOM   6189  C  CB  . PHE B 2 389 ? 111.250 113.631 91.884  1.00 277.21 ? 389 PHE B CB  1 
ATOM   6190  C  CG  . PHE B 2 389 ? 112.331 114.051 90.904  1.00 292.00 ? 389 PHE B CG  1 
ATOM   6191  C  CD1 . PHE B 2 389 ? 113.454 113.260 90.616  1.00 244.87 ? 389 PHE B CD1 1 
ATOM   6192  C  CD2 . PHE B 2 389 ? 112.218 115.281 90.258  1.00 319.99 ? 389 PHE B CD2 1 
ATOM   6193  C  CE1 . PHE B 2 389 ? 114.420 113.681 89.713  1.00 262.80 ? 389 PHE B CE1 1 
ATOM   6194  C  CE2 . PHE B 2 389 ? 113.186 115.704 89.354  1.00 360.18 ? 389 PHE B CE2 1 
ATOM   6195  C  CZ  . PHE B 2 389 ? 114.283 114.903 89.084  1.00 370.64 ? 389 PHE B CZ  1 
ATOM   6196  N  N   . SER B 2 390 ? 109.310 111.446 93.532  1.00 269.64 ? 390 SER B N   1 
ATOM   6197  C  CA  . SER B 2 390 ? 108.176 111.536 94.448  1.00 302.33 ? 390 SER B CA  1 
ATOM   6198  C  C   . SER B 2 390 ? 108.395 110.657 95.687  1.00 296.21 ? 390 SER B C   1 
ATOM   6199  O  O   . SER B 2 390 ? 108.728 109.481 95.559  1.00 224.83 ? 390 SER B O   1 
ATOM   6200  C  CB  . SER B 2 390 ? 106.880 111.183 93.747  1.00 293.05 ? 390 SER B CB  1 
ATOM   6201  O  OG  . SER B 2 390 ? 105.765 111.588 94.530  1.00 226.87 ? 390 SER B OG  1 
ATOM   6202  N  N   . LYS B 2 391 ? 108.191 111.237 96.886  1.00 320.86 ? 391 LYS B N   1 
ATOM   6203  C  CA  . LYS B 2 391 ? 108.391 110.550 98.161  1.00 317.42 ? 391 LYS B CA  1 
ATOM   6204  C  C   . LYS B 2 391 ? 107.328 109.465 98.374  1.00 295.18 ? 391 LYS B C   1 
ATOM   6205  O  O   . LYS B 2 391 ? 107.621 108.467 99.038  1.00 362.61 ? 391 LYS B O   1 
ATOM   6206  C  CB  . LYS B 2 391 ? 108.395 111.570 99.310  1.00 369.02 ? 391 LYS B CB  1 
ATOM   6207  C  CG  . LYS B 2 391 ? 108.618 111.022 100.719 1.00 424.83 ? 391 LYS B CG  1 
ATOM   6208  C  CD  . LYS B 2 391 ? 109.928 110.286 100.914 1.00 481.36 ? 391 LYS B CD  1 
ATOM   6209  C  CE  . LYS B 2 391 ? 110.170 109.890 102.358 1.00 532.54 ? 391 LYS B CE  1 
ATOM   6210  N  NZ  . LYS B 2 391 ? 111.504 109.272 102.548 1.00 554.80 ? 391 LYS B NZ  1 
ATOM   6211  N  N   . ASP B 2 392 ? 106.110 109.666 97.832  1.00 272.43 ? 392 ASP B N   1 
ATOM   6212  C  CA  . ASP B 2 392 ? 105.073 108.640 97.763  1.00 320.02 ? 392 ASP B CA  1 
ATOM   6213  C  C   . ASP B 2 392 ? 104.579 108.528 96.318  1.00 329.25 ? 392 ASP B C   1 
ATOM   6214  O  O   . ASP B 2 392 ? 104.652 109.492 95.557  1.00 300.97 ? 392 ASP B O   1 
ATOM   6215  C  CB  . ASP B 2 392 ? 103.934 108.930 98.748  1.00 381.27 ? 392 ASP B CB  1 
ATOM   6216  C  CG  . ASP B 2 392 ? 102.855 107.860 98.760  1.00 417.60 ? 392 ASP B CG  1 
ATOM   6217  O  OD1 . ASP B 2 392 ? 103.221 106.671 98.708  1.00 438.64 ? 392 ASP B OD1 1 
ATOM   6218  O  OD2 . ASP B 2 392 ? 101.658 108.217 98.812  1.00 453.33 ? 392 ASP B OD2 1 
ATOM   6219  N  N   . ILE B 2 393 ? 104.091 107.336 95.931  1.00 324.27 ? 393 ILE B N   1 
ATOM   6220  C  CA  . ILE B 2 393 ? 103.820 107.042 94.527  1.00 257.45 ? 393 ILE B CA  1 
ATOM   6221  C  C   . ILE B 2 393 ? 102.521 106.255 94.320  1.00 220.49 ? 393 ILE B C   1 
ATOM   6222  O  O   . ILE B 2 393 ? 101.799 106.615 93.407  1.00 132.02 ? 393 ILE B O   1 
ATOM   6223  C  CB  . ILE B 2 393 ? 105.053 106.345 93.895  1.00 228.72 ? 393 ILE B CB  1 
ATOM   6224  C  CG1 . ILE B 2 393 ? 104.864 106.067 92.398  1.00 223.95 ? 393 ILE B CG1 1 
ATOM   6225  C  CG2 . ILE B 2 393 ? 105.464 105.068 94.627  1.00 211.81 ? 393 ILE B CG2 1 
ATOM   6226  C  CD1 . ILE B 2 393 ? 104.636 107.317 91.586  1.00 193.58 ? 393 ILE B CD1 1 
ATOM   6227  N  N   . PHE B 2 394 ? 102.237 105.190 95.098  1.00 275.84 ? 394 PHE B N   1 
ATOM   6228  C  CA  . PHE B 2 394 ? 101.052 104.359 94.894  1.00 280.41 ? 394 PHE B CA  1 
ATOM   6229  C  C   . PHE B 2 394 ? 99.771  105.198 94.941  1.00 288.64 ? 394 PHE B C   1 
ATOM   6230  O  O   . PHE B 2 394 ? 98.860  104.951 94.156  1.00 281.38 ? 394 PHE B O   1 
ATOM   6231  C  CB  . PHE B 2 394 ? 100.997 103.221 95.923  1.00 301.48 ? 394 PHE B CB  1 
ATOM   6232  C  CG  . PHE B 2 394 ? 102.000 102.110 95.725  1.00 309.75 ? 394 PHE B CG  1 
ATOM   6233  C  CD1 . PHE B 2 394 ? 101.747 101.065 94.841  1.00 362.41 ? 394 PHE B CD1 1 
ATOM   6234  C  CD2 . PHE B 2 394 ? 103.201 102.101 96.425  1.00 335.37 ? 394 PHE B CD2 1 
ATOM   6235  C  CE1 . PHE B 2 394 ? 102.671 100.039 94.660  1.00 386.40 ? 394 PHE B CE1 1 
ATOM   6236  C  CE2 . PHE B 2 394 ? 104.125 101.077 96.242  1.00 385.13 ? 394 PHE B CE2 1 
ATOM   6237  C  CZ  . PHE B 2 394 ? 103.860 100.047 95.361  1.00 381.33 ? 394 PHE B CZ  1 
ATOM   6238  N  N   . SER B 2 395 ? 99.715  106.191 95.850  1.00 283.42 ? 395 SER B N   1 
ATOM   6239  C  CA  . SER B 2 395 ? 98.601  107.125 95.972  1.00 300.68 ? 395 SER B CA  1 
ATOM   6240  C  C   . SER B 2 395 ? 98.188  107.737 94.627  1.00 288.48 ? 395 SER B C   1 
ATOM   6241  O  O   . SER B 2 395 ? 96.993  107.819 94.333  1.00 196.46 ? 395 SER B O   1 
ATOM   6242  C  CB  . SER B 2 395 ? 98.945  108.204 96.978  1.00 344.70 ? 395 SER B CB  1 
ATOM   6243  O  OG  . SER B 2 395 ? 100.183 108.835 96.666  1.00 285.98 ? 395 SER B OG  1 
ATOM   6244  N  N   . VAL B 2 396 ? 99.166  108.160 93.808  1.00 255.55 ? 396 VAL B N   1 
ATOM   6245  C  CA  . VAL B 2 396 ? 98.888  108.862 92.558  1.00 241.94 ? 396 VAL B CA  1 
ATOM   6246  C  C   . VAL B 2 396 ? 98.180  107.940 91.558  1.00 198.87 ? 396 VAL B C   1 
ATOM   6247  O  O   . VAL B 2 396 ? 97.423  108.411 90.720  1.00 136.56 ? 396 VAL B O   1 
ATOM   6248  C  CB  . VAL B 2 396 ? 100.144 109.478 91.907  1.00 215.60 ? 396 VAL B CB  1 
ATOM   6249  C  CG1 . VAL B 2 396 ? 99.726  110.582 90.932  1.00 201.93 ? 396 VAL B CG1 1 
ATOM   6250  C  CG2 . VAL B 2 396 ? 101.178 109.996 92.917  1.00 219.22 ? 396 VAL B CG2 1 
ATOM   6251  N  N   . ILE B 2 397 ? 98.436  106.630 91.646  1.00 191.75 ? 397 ILE B N   1 
ATOM   6252  C  CA  . ILE B 2 397 ? 97.757  105.628 90.837  1.00 177.36 ? 397 ILE B CA  1 
ATOM   6253  C  C   . ILE B 2 397 ? 96.395  105.284 91.435  1.00 199.87 ? 397 ILE B C   1 
ATOM   6254  O  O   . ILE B 2 397 ? 95.427  105.099 90.676  1.00 256.85 ? 397 ILE B O   1 
ATOM   6255  C  CB  . ILE B 2 397 ? 98.685  104.401 90.661  1.00 214.78 ? 397 ILE B CB  1 
ATOM   6256  C  CG1 . ILE B 2 397 ? 99.653  104.642 89.497  1.00 181.47 ? 397 ILE B CG1 1 
ATOM   6257  C  CG2 . ILE B 2 397 ? 97.927  103.071 90.527  1.00 268.48 ? 397 ILE B CG2 1 
ATOM   6258  C  CD1 . ILE B 2 397 ? 99.010  104.537 88.138  1.00 207.17 ? 397 ILE B CD1 1 
ATOM   6259  N  N   . ASN B 2 398 ? 96.321  105.185 92.771  1.00 199.90 ? 398 ASN B N   1 
ATOM   6260  C  CA  . ASN B 2 398 ? 95.085  104.851 93.467  1.00 225.22 ? 398 ASN B CA  1 
ATOM   6261  C  C   . ASN B 2 398 ? 93.981  105.879 93.169  1.00 221.95 ? 398 ASN B C   1 
ATOM   6262  O  O   . ASN B 2 398 ? 92.795  105.509 93.118  1.00 140.09 ? 398 ASN B O   1 
ATOM   6263  C  CB  . ASN B 2 398 ? 95.376  104.642 94.961  1.00 290.90 ? 398 ASN B CB  1 
ATOM   6264  C  CG  . ASN B 2 398 ? 96.262  103.438 95.238  1.00 328.56 ? 398 ASN B CG  1 
ATOM   6265  O  OD1 . ASN B 2 398 ? 96.356  102.515 94.427  1.00 340.57 ? 398 ASN B OD1 1 
ATOM   6266  N  ND2 . ASN B 2 398 ? 96.921  103.432 96.387  1.00 326.15 ? 398 ASN B ND2 1 
ATOM   6267  N  N   . PHE B 2 399 ? 94.363  107.157 92.953  1.00 227.85 ? 399 PHE B N   1 
ATOM   6268  C  CA  . PHE B 2 399 ? 93.454  108.196 92.467  1.00 254.51 ? 399 PHE B CA  1 
ATOM   6269  C  C   . PHE B 2 399 ? 92.661  107.778 91.218  1.00 217.62 ? 399 PHE B C   1 
ATOM   6270  O  O   . PHE B 2 399 ? 91.601  108.338 90.977  1.00 231.26 ? 399 PHE B O   1 
ATOM   6271  C  CB  . PHE B 2 399 ? 94.223  109.498 92.195  1.00 211.49 ? 399 PHE B CB  1 
ATOM   6272  C  CG  . PHE B 2 399 ? 94.827  110.235 93.373  1.00 255.71 ? 399 PHE B CG  1 
ATOM   6273  C  CD1 . PHE B 2 399 ? 94.603  109.885 94.707  1.00 327.20 ? 399 PHE B CD1 1 
ATOM   6274  C  CD2 . PHE B 2 399 ? 95.656  111.325 93.130  1.00 350.00 ? 399 PHE B CD2 1 
ATOM   6275  C  CE1 . PHE B 2 399 ? 95.187  110.604 95.748  1.00 371.96 ? 399 PHE B CE1 1 
ATOM   6276  C  CE2 . PHE B 2 399 ? 96.241  112.040 94.170  1.00 409.86 ? 399 PHE B CE2 1 
ATOM   6277  C  CZ  . PHE B 2 399 ? 96.007  111.679 95.480  1.00 410.23 ? 399 PHE B CZ  1 
ATOM   6278  N  N   . PHE B 2 400 ? 93.152  106.819 90.427  1.00 180.84 ? 400 PHE B N   1 
ATOM   6279  C  CA  . PHE B 2 400 ? 92.523  106.416 89.180  1.00 169.72 ? 400 PHE B CA  1 
ATOM   6280  C  C   . PHE B 2 400 ? 92.100  104.953 89.179  1.00 172.35 ? 400 PHE B C   1 
ATOM   6281  O  O   . PHE B 2 400 ? 92.169  104.293 88.142  1.00 214.95 ? 400 PHE B O   1 
ATOM   6282  C  CB  . PHE B 2 400 ? 93.523  106.674 88.061  1.00 193.94 ? 400 PHE B CB  1 
ATOM   6283  C  CG  . PHE B 2 400 ? 93.830  108.128 87.873  1.00 198.13 ? 400 PHE B CG  1 
ATOM   6284  C  CD1 . PHE B 2 400 ? 92.952  108.931 87.166  1.00 204.41 ? 400 PHE B CD1 1 
ATOM   6285  C  CD2 . PHE B 2 400 ? 94.983  108.685 88.413  1.00 193.48 ? 400 PHE B CD2 1 
ATOM   6286  C  CE1 . PHE B 2 400 ? 93.245  110.276 86.988  1.00 251.90 ? 400 PHE B CE1 1 
ATOM   6287  C  CE2 . PHE B 2 400 ? 95.269  110.025 88.235  1.00 198.92 ? 400 PHE B CE2 1 
ATOM   6288  C  CZ  . PHE B 2 400 ? 94.402  110.823 87.529  1.00 254.15 ? 400 PHE B CZ  1 
ATOM   6289  N  N   . SER B 2 401 ? 91.663  104.436 90.329  1.00 186.09 ? 401 SER B N   1 
ATOM   6290  C  CA  . SER B 2 401 ? 91.175  103.062 90.433  1.00 231.72 ? 401 SER B CA  1 
ATOM   6291  C  C   . SER B 2 401 ? 90.127  102.761 89.347  1.00 216.74 ? 401 SER B C   1 
ATOM   6292  O  O   . SER B 2 401 ? 90.188  101.740 88.646  1.00 123.14 ? 401 SER B O   1 
ATOM   6293  C  CB  . SER B 2 401 ? 90.644  102.869 91.838  1.00 251.94 ? 401 SER B CB  1 
ATOM   6294  O  OG  . SER B 2 401 ? 90.072  101.591 92.030  1.00 230.45 ? 401 SER B OG  1 
ATOM   6295  N  N   . PHE B 2 402 ? 89.173  103.698 89.234  1.00 238.11 ? 402 PHE B N   1 
ATOM   6296  C  CA  . PHE B 2 402 ? 88.019  103.642 88.348  1.00 208.66 ? 402 PHE B CA  1 
ATOM   6297  C  C   . PHE B 2 402 ? 88.390  103.749 86.874  1.00 201.35 ? 402 PHE B C   1 
ATOM   6298  O  O   . PHE B 2 402 ? 87.624  103.271 86.042  1.00 223.23 ? 402 PHE B O   1 
ATOM   6299  C  CB  . PHE B 2 402 ? 87.029  104.770 88.689  1.00 230.89 ? 402 PHE B CB  1 
ATOM   6300  C  CG  . PHE B 2 402 ? 87.471  106.181 88.353  1.00 276.25 ? 402 PHE B CG  1 
ATOM   6301  C  CD1 . PHE B 2 402 ? 88.375  106.890 89.150  1.00 277.48 ? 402 PHE B CD1 1 
ATOM   6302  C  CD2 . PHE B 2 402 ? 86.965  106.824 87.229  1.00 298.76 ? 402 PHE B CD2 1 
ATOM   6303  C  CE1 . PHE B 2 402 ? 88.757  108.198 88.824  1.00 247.44 ? 402 PHE B CE1 1 
ATOM   6304  C  CE2 . PHE B 2 402 ? 87.354  108.122 86.904  1.00 271.17 ? 402 PHE B CE2 1 
ATOM   6305  C  CZ  . PHE B 2 402 ? 88.254  108.815 87.700  1.00 218.13 ? 402 PHE B CZ  1 
ATOM   6306  N  N   . PHE B 2 403 ? 89.532  104.372 86.551  1.00 208.27 ? 403 PHE B N   1 
ATOM   6307  C  CA  . PHE B 2 403 ? 89.824  104.836 85.203  1.00 218.49 ? 403 PHE B CA  1 
ATOM   6308  C  C   . PHE B 2 403 ? 90.032  103.690 84.201  1.00 179.11 ? 403 PHE B C   1 
ATOM   6309  O  O   . PHE B 2 403 ? 89.493  103.748 83.089  1.00 181.03 ? 403 PHE B O   1 
ATOM   6310  C  CB  . PHE B 2 403 ? 91.034  105.757 85.269  1.00 191.71 ? 403 PHE B CB  1 
ATOM   6311  C  CG  . PHE B 2 403 ? 91.448  106.311 83.938  1.00 231.45 ? 403 PHE B CG  1 
ATOM   6312  C  CD1 . PHE B 2 403 ? 90.840  107.448 83.423  1.00 250.99 ? 403 PHE B CD1 1 
ATOM   6313  C  CD2 . PHE B 2 403 ? 92.443  105.682 83.198  1.00 237.74 ? 403 PHE B CD2 1 
ATOM   6314  C  CE1 . PHE B 2 403 ? 91.235  107.956 82.195  1.00 272.20 ? 403 PHE B CE1 1 
ATOM   6315  C  CE2 . PHE B 2 403 ? 92.834  106.194 81.970  1.00 254.02 ? 403 PHE B CE2 1 
ATOM   6316  C  CZ  . PHE B 2 403 ? 92.230  107.328 81.475  1.00 264.71 ? 403 PHE B CZ  1 
ATOM   6317  N  N   . ASN B 2 404 ? 90.797  102.669 84.593  1.00 157.22 ? 404 ASN B N   1 
ATOM   6318  C  CA  . ASN B 2 404 ? 91.035  101.511 83.744  1.00 211.05 ? 404 ASN B CA  1 
ATOM   6319  C  C   . ASN B 2 404 ? 89.717  100.861 83.307  1.00 214.49 ? 404 ASN B C   1 
ATOM   6320  O  O   . ASN B 2 404 ? 89.457  100.673 82.112  1.00 252.67 ? 404 ASN B O   1 
ATOM   6321  C  CB  . ASN B 2 404 ? 91.896  100.446 84.441  1.00 252.66 ? 404 ASN B CB  1 
ATOM   6322  C  CG  . ASN B 2 404 ? 92.427  99.400  83.478  1.00 275.98 ? 404 ASN B CG  1 
ATOM   6323  O  OD1 . ASN B 2 404 ? 92.892  99.749  82.392  1.00 263.91 ? 404 ASN B OD1 1 
ATOM   6324  N  ND2 . ASN B 2 404 ? 92.354  98.128  83.850  1.00 257.49 ? 404 ASN B ND2 1 
ATOM   6325  N  N   . TRP B 2 405 ? 88.879  100.511 84.290  1.00 205.51 ? 405 TRP B N   1 
ATOM   6326  C  CA  . TRP B 2 405 ? 87.602  99.859  84.038  1.00 188.80 ? 405 TRP B CA  1 
ATOM   6327  C  C   . TRP B 2 405 ? 86.652  100.797 83.305  1.00 186.17 ? 405 TRP B C   1 
ATOM   6328  O  O   . TRP B 2 405 ? 85.879  100.320 82.487  1.00 201.69 ? 405 TRP B O   1 
ATOM   6329  C  CB  . TRP B 2 405 ? 86.975  99.357  85.347  1.00 205.88 ? 405 TRP B CB  1 
ATOM   6330  C  CG  . TRP B 2 405 ? 87.956  98.486  86.062  1.00 222.28 ? 405 TRP B CG  1 
ATOM   6331  C  CD1 . TRP B 2 405 ? 88.584  98.778  87.232  1.00 304.82 ? 405 TRP B CD1 1 
ATOM   6332  C  CD2 . TRP B 2 405 ? 88.449  97.202  85.625  1.00 238.46 ? 405 TRP B CD2 1 
ATOM   6333  N  NE1 . TRP B 2 405 ? 89.427  97.753  87.574  1.00 363.79 ? 405 TRP B NE1 1 
ATOM   6334  C  CE2 . TRP B 2 405 ? 89.372  96.774  86.609  1.00 325.85 ? 405 TRP B CE2 1 
ATOM   6335  C  CE3 . TRP B 2 405 ? 88.208  96.372  84.520  1.00 213.49 ? 405 TRP B CE3 1 
ATOM   6336  C  CZ2 . TRP B 2 405 ? 90.048  95.553  86.514  1.00 320.61 ? 405 TRP B CZ2 1 
ATOM   6337  C  CZ3 . TRP B 2 405 ? 88.880  95.170  84.425  1.00 259.70 ? 405 TRP B CZ3 1 
ATOM   6338  C  CH2 . TRP B 2 405 ? 89.788  94.766  85.410  1.00 303.32 ? 405 TRP B CH2 1 
ATOM   6339  N  N   . LEU B 2 406 ? 86.696  102.106 83.591  1.00 191.41 ? 406 LEU B N   1 
ATOM   6340  C  CA  . LEU B 2 406 ? 85.854  103.068 82.898  1.00 186.53 ? 406 LEU B CA  1 
ATOM   6341  C  C   . LEU B 2 406 ? 86.188  103.043 81.416  1.00 165.89 ? 406 LEU B C   1 
ATOM   6342  O  O   . LEU B 2 406 ? 85.278  102.965 80.596  1.00 172.44 ? 406 LEU B O   1 
ATOM   6343  C  CB  . LEU B 2 406 ? 86.023  104.466 83.514  1.00 199.96 ? 406 LEU B CB  1 
ATOM   6344  C  CG  . LEU B 2 406 ? 85.363  105.626 82.774  1.00 201.30 ? 406 LEU B CG  1 
ATOM   6345  C  CD1 . LEU B 2 406 ? 83.850  105.458 82.801  1.00 259.38 ? 406 LEU B CD1 1 
ATOM   6346  C  CD2 . LEU B 2 406 ? 85.813  106.954 83.371  1.00 197.78 ? 406 LEU B CD2 1 
ATOM   6347  N  N   . CYS B 2 407 ? 87.475  103.125 81.067  1.00 177.46 ? 407 CYS B N   1 
ATOM   6348  C  CA  . CYS B 2 407 ? 87.853  103.160 79.664  1.00 206.88 ? 407 CYS B CA  1 
ATOM   6349  C  C   . CYS B 2 407 ? 87.464  101.859 78.987  1.00 163.24 ? 407 CYS B C   1 
ATOM   6350  O  O   . CYS B 2 407 ? 87.027  101.910 77.838  1.00 189.50 ? 407 CYS B O   1 
ATOM   6351  C  CB  . CYS B 2 407 ? 89.326  103.503 79.517  1.00 227.23 ? 407 CYS B CB  1 
ATOM   6352  S  SG  . CYS B 2 407 ? 89.587  105.249 79.937  1.00 234.49 ? 407 CYS B SG  1 
ATOM   6353  N  N   . VAL B 2 408 ? 87.594  100.729 79.696  1.00 118.12 ? 408 VAL B N   1 
ATOM   6354  C  CA  . VAL B 2 408 ? 87.227  99.440  79.129  1.00 175.63 ? 408 VAL B CA  1 
ATOM   6355  C  C   . VAL B 2 408 ? 85.717  99.406  78.874  1.00 186.54 ? 408 VAL B C   1 
ATOM   6356  O  O   . VAL B 2 408 ? 85.282  99.003  77.800  1.00 192.91 ? 408 VAL B O   1 
ATOM   6357  C  CB  . VAL B 2 408 ? 87.725  98.272  80.007  1.00 223.09 ? 408 VAL B CB  1 
ATOM   6358  C  CG1 . VAL B 2 408 ? 87.037  96.957  79.678  1.00 227.73 ? 408 VAL B CG1 1 
ATOM   6359  C  CG2 . VAL B 2 408 ? 89.238  98.093  79.910  1.00 229.40 ? 408 VAL B CG2 1 
ATOM   6360  N  N   . ALA B 2 409 ? 84.925  99.832  79.855  1.00 170.55 ? 409 ALA B N   1 
ATOM   6361  C  CA  . ALA B 2 409 ? 83.482  99.893  79.698  1.00 211.47 ? 409 ALA B CA  1 
ATOM   6362  C  C   . ALA B 2 409 ? 83.103  100.781 78.503  1.00 210.60 ? 409 ALA B C   1 
ATOM   6363  O  O   . ALA B 2 409 ? 82.241  100.398 77.719  1.00 184.65 ? 409 ALA B O   1 
ATOM   6364  C  CB  . ALA B 2 409 ? 82.857  100.369 80.995  1.00 220.69 ? 409 ALA B CB  1 
ATOM   6365  N  N   . LEU B 2 410 ? 83.740  101.954 78.360  1.00 181.03 ? 410 LEU B N   1 
ATOM   6366  C  CA  . LEU B 2 410 ? 83.490  102.861 77.245  1.00 166.30 ? 410 LEU B CA  1 
ATOM   6367  C  C   . LEU B 2 410 ? 83.907  102.243 75.913  1.00 164.49 ? 410 LEU B C   1 
ATOM   6368  O  O   . LEU B 2 410 ? 83.210  102.450 74.928  1.00 205.24 ? 410 LEU B O   1 
ATOM   6369  C  CB  . LEU B 2 410 ? 84.213  104.184 77.497  1.00 176.85 ? 410 LEU B CB  1 
ATOM   6370  C  CG  . LEU B 2 410 ? 83.630  105.021 78.638  1.00 266.14 ? 410 LEU B CG  1 
ATOM   6371  C  CD1 . LEU B 2 410 ? 84.521  106.211 78.946  1.00 342.84 ? 410 LEU B CD1 1 
ATOM   6372  C  CD2 . LEU B 2 410 ? 82.223  105.502 78.312  1.00 292.16 ? 410 LEU B CD2 1 
ATOM   6373  N  N   . ALA B 2 411 ? 85.001  101.482 75.860  1.00 178.71 ? 411 ALA B N   1 
ATOM   6374  C  CA  . ALA B 2 411 ? 85.353  100.772 74.636  1.00 229.78 ? 411 ALA B CA  1 
ATOM   6375  C  C   . ALA B 2 411 ? 84.269  99.758  74.230  1.00 201.86 ? 411 ALA B C   1 
ATOM   6376  O  O   . ALA B 2 411 ? 83.875  99.722  73.057  1.00 219.98 ? 411 ALA B O   1 
ATOM   6377  C  CB  . ALA B 2 411 ? 86.708  100.116 74.803  1.00 314.29 ? 411 ALA B CB  1 
ATOM   6378  N  N   . ILE B 2 412 ? 83.775  98.938  75.178  1.00 145.95 ? 412 ILE B N   1 
ATOM   6379  C  CA  . ILE B 2 412 ? 82.835  97.883  74.815  1.00 182.80 ? 412 ILE B CA  1 
ATOM   6380  C  C   . ILE B 2 412 ? 81.435  98.461  74.576  1.00 220.23 ? 412 ILE B C   1 
ATOM   6381  O  O   . ILE B 2 412 ? 80.767  97.967  73.662  1.00 208.83 ? 412 ILE B O   1 
ATOM   6382  C  CB  . ILE B 2 412 ? 82.890  96.714  75.821  1.00 180.31 ? 412 ILE B CB  1 
ATOM   6383  C  CG1 . ILE B 2 412 ? 84.315  96.173  75.939  1.00 204.82 ? 412 ILE B CG1 1 
ATOM   6384  C  CG2 . ILE B 2 412 ? 81.940  95.583  75.429  1.00 194.97 ? 412 ILE B CG2 1 
ATOM   6385  C  CD1 . ILE B 2 412 ? 85.031  95.976  74.607  1.00 189.25 ? 412 ILE B CD1 1 
ATOM   6386  N  N   . ILE B 2 413 ? 80.998  99.491  75.331  1.00 212.02 ? 413 ILE B N   1 
ATOM   6387  C  CA  . ILE B 2 413 ? 79.837  100.296 74.937  1.00 207.75 ? 413 ILE B CA  1 
ATOM   6388  C  C   . ILE B 2 413 ? 80.008  100.801 73.499  1.00 186.01 ? 413 ILE B C   1 
ATOM   6389  O  O   . ILE B 2 413 ? 79.076  100.735 72.688  1.00 228.03 ? 413 ILE B O   1 
ATOM   6390  C  CB  . ILE B 2 413 ? 79.599  101.446 75.939  1.00 221.15 ? 413 ILE B CB  1 
ATOM   6391  C  CG1 . ILE B 2 413 ? 79.070  100.891 77.267  1.00 255.36 ? 413 ILE B CG1 1 
ATOM   6392  C  CG2 . ILE B 2 413 ? 78.668  102.517 75.366  1.00 295.47 ? 413 ILE B CG2 1 
ATOM   6393  C  CD1 . ILE B 2 413 ? 79.060  101.874 78.424  1.00 329.59 ? 413 ILE B CD1 1 
ATOM   6394  N  N   . GLY B 2 414 ? 81.203  101.298 73.192  1.00 175.46 ? 414 GLY B N   1 
ATOM   6395  C  CA  . GLY B 2 414 ? 81.539  101.653 71.831  1.00 185.20 ? 414 GLY B CA  1 
ATOM   6396  C  C   . GLY B 2 414 ? 81.286  100.508 70.850  1.00 226.05 ? 414 GLY B C   1 
ATOM   6397  O  O   . GLY B 2 414 ? 80.757  100.773 69.776  1.00 310.70 ? 414 GLY B O   1 
ATOM   6398  N  N   . MET B 2 415 ? 81.643  99.260  71.208  1.00 170.55 ? 415 MET B N   1 
ATOM   6399  C  CA  . MET B 2 415 ? 81.451  98.123  70.318  1.00 221.84 ? 415 MET B CA  1 
ATOM   6400  C  C   . MET B 2 415 ? 79.964  97.814  70.074  1.00 223.05 ? 415 MET B C   1 
ATOM   6401  O  O   . MET B 2 415 ? 79.600  97.405  68.960  1.00 210.10 ? 415 MET B O   1 
ATOM   6402  C  CB  . MET B 2 415 ? 82.163  96.885  70.864  1.00 226.44 ? 415 MET B CB  1 
ATOM   6403  C  CG  . MET B 2 415 ? 82.329  95.831  69.797  1.00 259.92 ? 415 MET B CG  1 
ATOM   6404  S  SD  . MET B 2 415 ? 83.267  94.393  70.288  1.00 248.77 ? 415 MET B SD  1 
ATOM   6405  C  CE  . MET B 2 415 ? 82.129  93.627  71.433  1.00 238.28 ? 415 MET B CE  1 
ATOM   6406  N  N   . ILE B 2 416 ? 79.102  98.030  71.078  1.00 230.94 ? 416 ILE B N   1 
ATOM   6407  C  CA  . ILE B 2 416 ? 77.657  97.945  70.876  1.00 232.82 ? 416 ILE B CA  1 
ATOM   6408  C  C   . ILE B 2 416 ? 77.234  98.981  69.821  1.00 200.30 ? 416 ILE B C   1 
ATOM   6409  O  O   . ILE B 2 416 ? 76.592  98.635  68.833  1.00 141.21 ? 416 ILE B O   1 
ATOM   6410  C  CB  . ILE B 2 416 ? 76.869  98.173  72.192  1.00 337.26 ? 416 ILE B CB  1 
ATOM   6411  C  CG1 . ILE B 2 416 ? 77.369  97.339  73.381  1.00 373.00 ? 416 ILE B CG1 1 
ATOM   6412  C  CG2 . ILE B 2 416 ? 75.364  97.988  71.977  1.00 366.28 ? 416 ILE B CG2 1 
ATOM   6413  C  CD1 . ILE B 2 416 ? 77.312  95.840  73.195  1.00 334.09 ? 416 ILE B CD1 1 
ATOM   6414  N  N   . TRP B 2 417 ? 77.582  100.261 70.053  1.00 236.11 ? 417 TRP B N   1 
ATOM   6415  C  CA  . TRP B 2 417 ? 77.159  101.393 69.228  1.00 228.04 ? 417 TRP B CA  1 
ATOM   6416  C  C   . TRP B 2 417 ? 77.704  101.259 67.798  1.00 237.78 ? 417 TRP B C   1 
ATOM   6417  O  O   . TRP B 2 417 ? 77.015  101.569 66.832  1.00 277.01 ? 417 TRP B O   1 
ATOM   6418  C  CB  . TRP B 2 417 ? 77.591  102.694 69.924  1.00 226.89 ? 417 TRP B CB  1 
ATOM   6419  C  CG  . TRP B 2 417 ? 76.999  103.974 69.396  1.00 242.10 ? 417 TRP B CG  1 
ATOM   6420  C  CD1 . TRP B 2 417 ? 76.036  104.109 68.443  1.00 261.16 ? 417 TRP B CD1 1 
ATOM   6421  C  CD2 . TRP B 2 417 ? 77.362  105.322 69.799  1.00 324.30 ? 417 TRP B CD2 1 
ATOM   6422  N  NE1 . TRP B 2 417 ? 75.773  105.440 68.228  1.00 363.94 ? 417 TRP B NE1 1 
ATOM   6423  C  CE2 . TRP B 2 417 ? 76.568  106.212 69.041  1.00 342.20 ? 417 TRP B CE2 1 
ATOM   6424  C  CE3 . TRP B 2 417 ? 78.275  105.869 70.718  1.00 385.28 ? 417 TRP B CE3 1 
ATOM   6425  C  CZ2 . TRP B 2 417 ? 76.664  107.605 69.179  1.00 313.99 ? 417 TRP B CZ2 1 
ATOM   6426  C  CZ3 . TRP B 2 417 ? 78.370  107.244 70.854  1.00 346.19 ? 417 TRP B CZ3 1 
ATOM   6427  C  CH2 . TRP B 2 417 ? 77.576  108.102 70.088  1.00 258.39 ? 417 TRP B CH2 1 
ATOM   6428  N  N   . LEU B 2 418 ? 78.935  100.746 67.676  1.00 248.89 ? 418 LEU B N   1 
ATOM   6429  C  CA  . LEU B 2 418 ? 79.577  100.465 66.395  1.00 256.07 ? 418 LEU B CA  1 
ATOM   6430  C  C   . LEU B 2 418 ? 78.857  99.362  65.599  1.00 246.86 ? 418 LEU B C   1 
ATOM   6431  O  O   . LEU B 2 418 ? 78.808  99.431  64.371  1.00 255.91 ? 418 LEU B O   1 
ATOM   6432  C  CB  . LEU B 2 418 ? 81.032  100.085 66.688  1.00 289.30 ? 418 LEU B CB  1 
ATOM   6433  C  CG  . LEU B 2 418 ? 81.974  100.028 65.489  1.00 351.19 ? 418 LEU B CG  1 
ATOM   6434  C  CD1 . LEU B 2 418 ? 82.278  101.424 64.953  1.00 382.63 ? 418 LEU B CD1 1 
ATOM   6435  C  CD2 . LEU B 2 418 ? 83.260  99.317  65.873  1.00 392.07 ? 418 LEU B CD2 1 
ATOM   6436  N  N   . ARG B 2 419 ? 78.293  98.346  66.268  1.00 224.64 ? 419 ARG B N   1 
ATOM   6437  C  CA  . ARG B 2 419 ? 77.465  97.354  65.580  1.00 257.55 ? 419 ARG B CA  1 
ATOM   6438  C  C   . ARG B 2 419 ? 76.144  97.951  65.064  1.00 325.39 ? 419 ARG B C   1 
ATOM   6439  O  O   . ARG B 2 419 ? 75.744  97.583  63.969  1.00 304.12 ? 419 ARG B O   1 
ATOM   6440  C  CB  . ARG B 2 419 ? 77.174  96.151  66.477  1.00 266.23 ? 419 ARG B CB  1 
ATOM   6441  C  CG  . ARG B 2 419 ? 78.320  95.160  66.570  1.00 293.75 ? 419 ARG B CG  1 
ATOM   6442  C  CD  . ARG B 2 419 ? 77.901  93.978  67.409  1.00 346.16 ? 419 ARG B CD  1 
ATOM   6443  N  NE  . ARG B 2 419 ? 78.931  92.961  67.584  1.00 310.22 ? 419 ARG B NE  1 
ATOM   6444  C  CZ  . ARG B 2 419 ? 78.717  91.719  68.021  1.00 295.09 ? 419 ARG B CZ  1 
ATOM   6445  N  NH1 . ARG B 2 419 ? 79.740  90.905  68.174  1.00 287.16 ? 419 ARG B NH1 1 
ATOM   6446  N  NH2 . ARG B 2 419 ? 77.504  91.267  68.301  1.00 297.94 ? 419 ARG B NH2 1 
ATOM   6447  N  N   . HIS B 2 420 ? 75.463  98.845  65.817  1.00 394.57 ? 420 HIS B N   1 
ATOM   6448  C  CA  . HIS B 2 420 ? 74.264  99.539  65.326  1.00 331.37 ? 420 HIS B CA  1 
ATOM   6449  C  C   . HIS B 2 420 ? 74.577  100.481 64.159  1.00 288.84 ? 420 HIS B C   1 
ATOM   6450  O  O   . HIS B 2 420 ? 73.842  100.482 63.169  1.00 256.77 ? 420 HIS B O   1 
ATOM   6451  C  CB  . HIS B 2 420 ? 73.558  100.365 66.419  1.00 318.11 ? 420 HIS B CB  1 
ATOM   6452  C  CG  . HIS B 2 420 ? 72.910  99.577  67.509  1.00 401.59 ? 420 HIS B CG  1 
ATOM   6453  N  ND1 . HIS B 2 420 ? 72.231  100.164 68.559  1.00 384.62 ? 420 HIS B ND1 1 
ATOM   6454  C  CD2 . HIS B 2 420 ? 72.827  98.257  67.702  1.00 457.08 ? 420 HIS B CD2 1 
ATOM   6455  C  CE1 . HIS B 2 420 ? 71.760  99.217  69.362  1.00 394.96 ? 420 HIS B CE1 1 
ATOM   6456  N  NE2 . HIS B 2 420 ? 72.110  98.050  68.860  1.00 430.35 ? 420 HIS B NE2 1 
ATOM   6457  N  N   . ARG B 2 421 ? 75.660  101.271 64.286  1.00 320.11 ? 421 ARG B N   1 
ATOM   6458  C  CA  . ARG B 2 421 ? 75.964  102.348 63.354  1.00 320.31 ? 421 ARG B CA  1 
ATOM   6459  C  C   . ARG B 2 421 ? 76.505  101.819 62.019  1.00 300.77 ? 421 ARG B C   1 
ATOM   6460  O  O   . ARG B 2 421 ? 76.115  102.360 60.985  1.00 276.74 ? 421 ARG B O   1 
ATOM   6461  C  CB  . ARG B 2 421 ? 76.945  103.346 63.988  1.00 297.20 ? 421 ARG B CB  1 
ATOM   6462  C  CG  . ARG B 2 421 ? 77.381  104.464 63.051  1.00 311.58 ? 421 ARG B CG  1 
ATOM   6463  C  CD  . ARG B 2 421 ? 77.893  105.691 63.789  1.00 335.92 ? 421 ARG B CD  1 
ATOM   6464  N  NE  . ARG B 2 421 ? 76.805  106.518 64.308  1.00 365.33 ? 421 ARG B NE  1 
ATOM   6465  C  CZ  . ARG B 2 421 ? 76.945  107.753 64.793  1.00 368.64 ? 421 ARG B CZ  1 
ATOM   6466  N  NH1 . ARG B 2 421 ? 75.875  108.475 65.093  1.00 312.90 ? 421 ARG B NH1 1 
ATOM   6467  N  NH2 . ARG B 2 421 ? 78.149  108.278 64.970  1.00 360.89 ? 421 ARG B NH2 1 
ATOM   6468  N  N   . LYS B 2 422 ? 77.396  100.805 62.021  1.00 266.71 ? 422 LYS B N   1 
ATOM   6469  C  CA  . LYS B 2 422 ? 78.008  100.338 60.770  1.00 289.48 ? 422 LYS B CA  1 
ATOM   6470  C  C   . LYS B 2 422 ? 78.176  98.807  60.717  1.00 288.95 ? 422 LYS B C   1 
ATOM   6471  O  O   . LYS B 2 422 ? 79.297  98.277  60.746  1.00 347.33 ? 422 LYS B O   1 
ATOM   6472  C  CB  . LYS B 2 422 ? 79.313  101.101 60.488  1.00 338.07 ? 422 LYS B CB  1 
ATOM   6473  C  CG  . LYS B 2 422 ? 80.371  101.183 61.586  1.00 398.89 ? 422 LYS B CG  1 
ATOM   6474  C  CD  . LYS B 2 422 ? 81.409  102.267 61.326  1.00 397.54 ? 422 LYS B CD  1 
ATOM   6475  C  CE  . LYS B 2 422 ? 82.173  102.109 60.026  1.00 385.25 ? 422 LYS B CE  1 
ATOM   6476  N  NZ  . LYS B 2 422 ? 83.216  103.153 59.884  1.00 383.50 ? 422 LYS B NZ  1 
ATOM   6477  N  N   . PRO B 2 423 ? 77.054  98.045  60.586  1.00 334.35 ? 423 PRO B N   1 
ATOM   6478  C  CA  . PRO B 2 423 ? 77.087  96.588  60.393  1.00 357.50 ? 423 PRO B CA  1 
ATOM   6479  C  C   . PRO B 2 423 ? 77.919  96.078  59.211  1.00 334.04 ? 423 PRO B C   1 
ATOM   6480  O  O   . PRO B 2 423 ? 78.339  94.922  59.236  1.00 332.01 ? 423 PRO B O   1 
ATOM   6481  C  CB  . PRO B 2 423 ? 75.613  96.198  60.141  1.00 375.45 ? 423 PRO B CB  1 
ATOM   6482  C  CG  . PRO B 2 423 ? 74.804  97.320  60.746  1.00 383.79 ? 423 PRO B CG  1 
ATOM   6483  C  CD  . PRO B 2 423 ? 75.672  98.553  60.613  1.00 366.64 ? 423 PRO B CD  1 
ATOM   6484  N  N   . GLU B 2 424 ? 78.148  96.935  58.197  1.00 302.04 ? 424 GLU B N   1 
ATOM   6485  C  CA  . GLU B 2 424 ? 78.888  96.568  56.992  1.00 356.94 ? 424 GLU B CA  1 
ATOM   6486  C  C   . GLU B 2 424 ? 80.411  96.525  57.200  1.00 354.57 ? 424 GLU B C   1 
ATOM   6487  O  O   . GLU B 2 424 ? 81.109  95.981  56.336  1.00 344.37 ? 424 GLU B O   1 
ATOM   6488  C  CB  . GLU B 2 424 ? 78.491  97.484  55.821  1.00 402.94 ? 424 GLU B CB  1 
ATOM   6489  C  CG  . GLU B 2 424 ? 78.999  98.931  55.852  1.00 407.62 ? 424 GLU B CG  1 
ATOM   6490  C  CD  . GLU B 2 424 ? 78.194  99.944  56.650  1.00 399.42 ? 424 GLU B CD  1 
ATOM   6491  O  OE1 . GLU B 2 424 ? 77.453  99.529  57.573  1.00 360.96 ? 424 GLU B OE1 1 
ATOM   6492  O  OE2 . GLU B 2 424 ? 78.312  101.147 56.354  1.00 443.11 ? 424 GLU B OE2 1 
ATOM   6493  N  N   . LEU B 2 425 ? 80.934  97.081  58.310  1.00 359.04 ? 425 LEU B N   1 
ATOM   6494  C  CA  . LEU B 2 425 ? 82.368  97.045  58.584  1.00 328.19 ? 425 LEU B CA  1 
ATOM   6495  C  C   . LEU B 2 425 ? 82.819  95.613  58.917  1.00 267.28 ? 425 LEU B C   1 
ATOM   6496  O  O   . LEU B 2 425 ? 82.164  94.905  59.684  1.00 212.26 ? 425 LEU B O   1 
ATOM   6497  C  CB  . LEU B 2 425 ? 82.684  98.036  59.716  1.00 345.91 ? 425 LEU B CB  1 
ATOM   6498  C  CG  . LEU B 2 425 ? 84.165  98.193  60.063  1.00 383.60 ? 425 LEU B CG  1 
ATOM   6499  C  CD1 . LEU B 2 425 ? 84.939  98.811  58.905  1.00 379.53 ? 425 LEU B CD1 1 
ATOM   6500  C  CD2 . LEU B 2 425 ? 84.345  99.029  61.322  1.00 398.89 ? 425 LEU B CD2 1 
ATOM   6501  N  N   . GLU B 2 426 ? 83.961  95.199  58.338  1.00 262.43 ? 426 GLU B N   1 
ATOM   6502  C  CA  . GLU B 2 426 ? 84.425  93.812  58.361  1.00 327.15 ? 426 GLU B CA  1 
ATOM   6503  C  C   . GLU B 2 426 ? 84.753  93.332  59.786  1.00 307.83 ? 426 GLU B C   1 
ATOM   6504  O  O   . GLU B 2 426 ? 85.397  94.042  60.572  1.00 337.90 ? 426 GLU B O   1 
ATOM   6505  C  CB  . GLU B 2 426 ? 85.647  93.656  57.445  1.00 387.53 ? 426 GLU B CB  1 
ATOM   6506  C  CG  . GLU B 2 426 ? 86.173  92.228  57.319  1.00 414.85 ? 426 GLU B CG  1 
ATOM   6507  C  CD  . GLU B 2 426 ? 87.492  92.075  56.577  1.00 422.85 ? 426 GLU B CD  1 
ATOM   6508  O  OE1 . GLU B 2 426 ? 87.869  92.995  55.822  1.00 445.17 ? 426 GLU B OE1 1 
ATOM   6509  O  OE2 . GLU B 2 426 ? 88.149  91.031  56.761  1.00 383.17 ? 426 GLU B OE2 1 
ATOM   6510  N  N   . ARG B 2 427 ? 84.314  92.091  60.094  1.00 274.16 ? 427 ARG B N   1 
ATOM   6511  C  CA  . ARG B 2 427 ? 84.360  91.503  61.425  1.00 249.40 ? 427 ARG B CA  1 
ATOM   6512  C  C   . ARG B 2 427 ? 84.736  90.019  61.316  1.00 222.61 ? 427 ARG B C   1 
ATOM   6513  O  O   . ARG B 2 427 ? 83.860  89.161  61.232  1.00 250.47 ? 427 ARG B O   1 
ATOM   6514  C  CB  . ARG B 2 427 ? 83.010  91.714  62.120  1.00 251.18 ? 427 ARG B CB  1 
ATOM   6515  C  CG  . ARG B 2 427 ? 82.803  93.121  62.662  1.00 239.88 ? 427 ARG B CG  1 
ATOM   6516  C  CD  . ARG B 2 427 ? 81.379  93.400  63.090  1.00 269.54 ? 427 ARG B CD  1 
ATOM   6517  N  NE  . ARG B 2 427 ? 81.269  94.704  63.737  1.00 280.90 ? 427 ARG B NE  1 
ATOM   6518  C  CZ  . ARG B 2 427 ? 80.798  95.823  63.181  1.00 249.25 ? 427 ARG B CZ  1 
ATOM   6519  N  NH1 . ARG B 2 427 ? 80.560  96.887  63.930  1.00 175.25 ? 427 ARG B NH1 1 
ATOM   6520  N  NH2 . ARG B 2 427 ? 80.553  95.892  61.882  1.00 306.47 ? 427 ARG B NH2 1 
ATOM   6521  N  N   . PRO B 2 428 ? 86.043  89.657  61.308  1.00 240.27 ? 428 PRO B N   1 
ATOM   6522  C  CA  . PRO B 2 428 ? 86.461  88.247  61.372  1.00 250.18 ? 428 PRO B CA  1 
ATOM   6523  C  C   . PRO B 2 428 ? 86.063  87.527  62.669  1.00 265.50 ? 428 PRO B C   1 
ATOM   6524  O  O   . PRO B 2 428 ? 85.903  86.308  62.649  1.00 241.62 ? 428 PRO B O   1 
ATOM   6525  C  CB  . PRO B 2 428 ? 87.997  88.301  61.255  1.00 267.98 ? 428 PRO B CB  1 
ATOM   6526  C  CG  . PRO B 2 428 ? 88.310  89.703  60.730  1.00 297.57 ? 428 PRO B CG  1 
ATOM   6527  C  CD  . PRO B 2 428 ? 87.191  90.586  61.242  1.00 301.73 ? 428 PRO B CD  1 
ATOM   6528  N  N   . ILE B 2 429 ? 85.912  88.301  63.762  1.00 250.66 ? 429 ILE B N   1 
ATOM   6529  C  CA  . ILE B 2 429 ? 85.345  87.856  65.028  1.00 245.50 ? 429 ILE B CA  1 
ATOM   6530  C  C   . ILE B 2 429 ? 83.974  88.522  65.222  1.00 268.21 ? 429 ILE B C   1 
ATOM   6531  O  O   . ILE B 2 429 ? 83.841  89.726  64.992  1.00 223.04 ? 429 ILE B O   1 
ATOM   6532  C  CB  . ILE B 2 429 ? 86.332  88.184  66.174  1.00 266.14 ? 429 ILE B CB  1 
ATOM   6533  C  CG1 . ILE B 2 429 ? 87.677  87.470  66.009  1.00 345.00 ? 429 ILE B CG1 1 
ATOM   6534  C  CG2 . ILE B 2 429 ? 85.737  87.893  67.546  1.00 303.08 ? 429 ILE B CG2 1 
ATOM   6535  C  CD1 . ILE B 2 429 ? 87.626  85.943  66.140  1.00 341.21 ? 429 ILE B CD1 1 
ATOM   6536  N  N   . LYS B 2 430 ? 82.973  87.729  65.658  1.00 283.51 ? 430 LYS B N   1 
ATOM   6537  C  CA  . LYS B 2 430 ? 81.614  88.196  65.908  1.00 293.36 ? 430 LYS B CA  1 
ATOM   6538  C  C   . LYS B 2 430 ? 81.057  87.446  67.122  1.00 326.25 ? 430 LYS B C   1 
ATOM   6539  O  O   . LYS B 2 430 ? 80.387  86.424  66.977  1.00 322.66 ? 430 LYS B O   1 
ATOM   6540  C  CB  . LYS B 2 430 ? 80.759  88.004  64.647  1.00 281.01 ? 430 LYS B CB  1 
ATOM   6541  C  CG  . LYS B 2 430 ? 79.332  88.545  64.705  1.00 346.47 ? 430 LYS B CG  1 
ATOM   6542  C  CD  . LYS B 2 430 ? 79.190  90.023  64.363  1.00 410.08 ? 430 LYS B CD  1 
ATOM   6543  C  CE  . LYS B 2 430 ? 77.747  90.480  64.394  1.00 415.95 ? 430 LYS B CE  1 
ATOM   6544  N  NZ  . LYS B 2 430 ? 77.568  91.838  63.827  1.00 390.06 ? 430 LYS B NZ  1 
ATOM   6545  N  N   . VAL B 2 431 ? 81.346  87.975  68.321  1.00 355.74 ? 431 VAL B N   1 
ATOM   6546  C  CA  . VAL B 2 431 ? 80.961  87.392  69.603  1.00 350.93 ? 431 VAL B CA  1 
ATOM   6547  C  C   . VAL B 2 431 ? 79.459  87.596  69.853  1.00 375.91 ? 431 VAL B C   1 
ATOM   6548  O  O   . VAL B 2 431 ? 78.901  88.632  69.487  1.00 300.69 ? 431 VAL B O   1 
ATOM   6549  C  CB  . VAL B 2 431 ? 81.831  88.006  70.727  1.00 317.88 ? 431 VAL B CB  1 
ATOM   6550  C  CG1 . VAL B 2 431 ? 81.368  87.636  72.124  1.00 327.45 ? 431 VAL B CG1 1 
ATOM   6551  C  CG2 . VAL B 2 431 ? 83.294  87.630  70.571  1.00 307.41 ? 431 VAL B CG2 1 
ATOM   6552  N  N   . ASN B 2 432 ? 78.806  86.604  70.490  1.00 404.86 ? 432 ASN B N   1 
ATOM   6553  C  CA  . ASN B 2 432 ? 77.399  86.675  70.884  1.00 382.34 ? 432 ASN B CA  1 
ATOM   6554  C  C   . ASN B 2 432 ? 77.168  87.875  71.810  1.00 288.94 ? 432 ASN B C   1 
ATOM   6555  O  O   . ASN B 2 432 ? 77.842  87.995  72.828  1.00 287.42 ? 432 ASN B O   1 
ATOM   6556  C  CB  . ASN B 2 432 ? 76.927  85.385  71.578  1.00 406.86 ? 432 ASN B CB  1 
ATOM   6557  C  CG  . ASN B 2 432 ? 76.774  84.176  70.669  1.00 388.75 ? 432 ASN B CG  1 
ATOM   6558  O  OD1 . ASN B 2 432 ? 76.224  84.283  69.574  1.00 393.38 ? 432 ASN B OD1 1 
ATOM   6559  N  ND2 . ASN B 2 432 ? 77.245  83.016  71.107  1.00 329.06 ? 432 ASN B ND2 1 
ATOM   6560  N  N   . LEU B 2 433 ? 76.207  88.754  71.464  1.00 258.39 ? 433 LEU B N   1 
ATOM   6561  C  CA  . LEU B 2 433 ? 76.054  90.079  72.073  1.00 295.07 ? 433 LEU B CA  1 
ATOM   6562  C  C   . LEU B 2 433 ? 75.812  90.017  73.591  1.00 309.25 ? 433 LEU B C   1 
ATOM   6563  O  O   . LEU B 2 433 ? 76.018  91.021  74.288  1.00 319.24 ? 433 LEU B O   1 
ATOM   6564  C  CB  . LEU B 2 433 ? 74.902  90.810  71.355  1.00 344.35 ? 433 LEU B CB  1 
ATOM   6565  C  CG  . LEU B 2 433 ? 74.658  92.273  71.734  1.00 353.84 ? 433 LEU B CG  1 
ATOM   6566  C  CD1 . LEU B 2 433 ? 75.884  93.113  71.417  1.00 360.67 ? 433 LEU B CD1 1 
ATOM   6567  C  CD2 . LEU B 2 433 ? 73.428  92.829  71.028  1.00 366.21 ? 433 LEU B CD2 1 
ATOM   6568  N  N   . ALA B 2 434 ? 75.376  88.852  74.109  1.00 290.58 ? 434 ALA B N   1 
ATOM   6569  C  CA  . ALA B 2 434 ? 75.302  88.570  75.539  1.00 337.30 ? 434 ALA B CA  1 
ATOM   6570  C  C   . ALA B 2 434 ? 76.586  88.952  76.293  1.00 309.37 ? 434 ALA B C   1 
ATOM   6571  O  O   . ALA B 2 434 ? 76.500  89.577  77.362  1.00 178.80 ? 434 ALA B O   1 
ATOM   6572  C  CB  . ALA B 2 434 ? 74.968  87.106  75.735  1.00 358.31 ? 434 ALA B CB  1 
ATOM   6573  N  N   . LEU B 2 435 ? 77.764  88.584  75.741  1.00 296.17 ? 435 LEU B N   1 
ATOM   6574  C  CA  . LEU B 2 435 ? 79.034  88.733  76.448  1.00 248.69 ? 435 LEU B CA  1 
ATOM   6575  C  C   . LEU B 2 435 ? 79.372  90.218  76.619  1.00 186.23 ? 435 LEU B C   1 
ATOM   6576  O  O   . LEU B 2 435 ? 79.524  90.640  77.760  1.00 213.18 ? 435 LEU B O   1 
ATOM   6577  C  CB  . LEU B 2 435 ? 80.151  87.917  75.760  1.00 224.63 ? 435 LEU B CB  1 
ATOM   6578  C  CG  . LEU B 2 435 ? 80.072  86.386  75.887  1.00 268.53 ? 435 LEU B CG  1 
ATOM   6579  C  CD1 . LEU B 2 435 ? 81.398  85.742  75.494  1.00 235.53 ? 435 LEU B CD1 1 
ATOM   6580  C  CD2 . LEU B 2 435 ? 79.653  85.910  77.283  1.00 294.91 ? 435 LEU B CD2 1 
ATOM   6581  N  N   . PRO B 2 436 ? 79.509  91.062  75.566  1.00 165.43 ? 436 PRO B N   1 
ATOM   6582  C  CA  . PRO B 2 436 ? 79.617  92.516  75.745  1.00 218.85 ? 436 PRO B CA  1 
ATOM   6583  C  C   . PRO B 2 436 ? 78.634  93.139  76.738  1.00 213.39 ? 436 PRO B C   1 
ATOM   6584  O  O   . PRO B 2 436 ? 79.080  93.889  77.586  1.00 225.58 ? 436 PRO B O   1 
ATOM   6585  C  CB  . PRO B 2 436 ? 79.385  93.076  74.334  1.00 249.98 ? 436 PRO B CB  1 
ATOM   6586  C  CG  . PRO B 2 436 ? 79.987  92.007  73.468  1.00 265.08 ? 436 PRO B CG  1 
ATOM   6587  C  CD  . PRO B 2 436 ? 79.605  90.707  74.145  1.00 218.04 ? 436 PRO B CD  1 
ATOM   6588  N  N   . VAL B 2 437 ? 77.339  92.828  76.672  1.00 214.40 ? 437 VAL B N   1 
ATOM   6589  C  CA  . VAL B 2 437 ? 76.376  93.480  77.556  1.00 290.76 ? 437 VAL B CA  1 
ATOM   6590  C  C   . VAL B 2 437 ? 76.596  93.039  79.012  1.00 264.17 ? 437 VAL B C   1 
ATOM   6591  O  O   . VAL B 2 437 ? 76.529  93.883  79.910  1.00 197.54 ? 437 VAL B O   1 
ATOM   6592  C  CB  . VAL B 2 437 ? 74.927  93.252  77.072  1.00 380.66 ? 437 VAL B CB  1 
ATOM   6593  C  CG1 . VAL B 2 437 ? 73.887  93.776  78.058  1.00 418.97 ? 437 VAL B CG1 1 
ATOM   6594  C  CG2 . VAL B 2 437 ? 74.710  93.873  75.698  1.00 391.47 ? 437 VAL B CG2 1 
ATOM   6595  N  N   . PHE B 2 438 ? 76.852  91.738  79.240  1.00 239.71 ? 438 PHE B N   1 
ATOM   6596  C  CA  . PHE B 2 438 ? 77.223  91.202  80.550  1.00 304.23 ? 438 PHE B CA  1 
ATOM   6597  C  C   . PHE B 2 438 ? 78.449  91.919  81.127  1.00 257.80 ? 438 PHE B C   1 
ATOM   6598  O  O   . PHE B 2 438 ? 78.470  92.355  82.279  1.00 244.59 ? 438 PHE B O   1 
ATOM   6599  C  CB  . PHE B 2 438 ? 77.454  89.689  80.432  1.00 345.91 ? 438 PHE B CB  1 
ATOM   6600  C  CG  . PHE B 2 438 ? 78.147  89.005  81.588  1.00 422.05 ? 438 PHE B CG  1 
ATOM   6601  C  CD1 . PHE B 2 438 ? 79.532  88.907  81.646  1.00 414.55 ? 438 PHE B CD1 1 
ATOM   6602  C  CD2 . PHE B 2 438 ? 77.410  88.450  82.626  1.00 456.09 ? 438 PHE B CD2 1 
ATOM   6603  C  CE1 . PHE B 2 438 ? 80.161  88.269  82.710  1.00 398.94 ? 438 PHE B CE1 1 
ATOM   6604  C  CE2 . PHE B 2 438 ? 78.038  87.810  83.690  1.00 421.71 ? 438 PHE B CE2 1 
ATOM   6605  C  CZ  . PHE B 2 438 ? 79.414  87.721  83.732  1.00 393.73 ? 438 PHE B CZ  1 
ATOM   6606  N  N   . PHE B 2 439 ? 79.480  92.030  80.302  1.00 223.69 ? 439 PHE B N   1 
ATOM   6607  C  CA  . PHE B 2 439 ? 80.734  92.637  80.697  1.00 223.94 ? 439 PHE B CA  1 
ATOM   6608  C  C   . PHE B 2 439 ? 80.580  94.138  80.984  1.00 247.44 ? 439 PHE B C   1 
ATOM   6609  O  O   . PHE B 2 439 ? 81.153  94.626  81.952  1.00 268.85 ? 439 PHE B O   1 
ATOM   6610  C  CB  . PHE B 2 439 ? 81.733  92.340  79.577  1.00 248.83 ? 439 PHE B CB  1 
ATOM   6611  C  CG  . PHE B 2 439 ? 83.119  92.839  79.846  1.00 221.07 ? 439 PHE B CG  1 
ATOM   6612  C  CD1 . PHE B 2 439 ? 83.861  92.261  80.850  1.00 195.58 ? 439 PHE B CD1 1 
ATOM   6613  C  CD2 . PHE B 2 439 ? 83.659  93.888  79.110  1.00 217.04 ? 439 PHE B CD2 1 
ATOM   6614  C  CE1 . PHE B 2 439 ? 85.134  92.732  81.122  1.00 220.41 ? 439 PHE B CE1 1 
ATOM   6615  C  CE2 . PHE B 2 439 ? 84.933  94.352  79.376  1.00 216.01 ? 439 PHE B CE2 1 
ATOM   6616  C  CZ  . PHE B 2 439 ? 85.671  93.772  80.384  1.00 268.47 ? 439 PHE B CZ  1 
ATOM   6617  N  N   . ILE B 2 440 ? 79.829  94.881  80.150  1.00 227.35 ? 440 ILE B N   1 
ATOM   6618  C  CA  . ILE B 2 440 ? 79.530  96.289  80.386  1.00 241.26 ? 440 ILE B CA  1 
ATOM   6619  C  C   . ILE B 2 440 ? 78.803  96.432  81.719  1.00 248.23 ? 440 ILE B C   1 
ATOM   6620  O  O   . ILE B 2 440 ? 79.223  97.238  82.553  1.00 245.49 ? 440 ILE B O   1 
ATOM   6621  C  CB  . ILE B 2 440 ? 78.700  96.911  79.237  1.00 256.02 ? 440 ILE B CB  1 
ATOM   6622  C  CG1 . ILE B 2 440 ? 79.499  97.029  77.937  1.00 278.57 ? 440 ILE B CG1 1 
ATOM   6623  C  CG2 . ILE B 2 440 ? 78.111  98.271  79.618  1.00 260.71 ? 440 ILE B CG2 1 
ATOM   6624  C  CD1 . ILE B 2 440 ? 78.620  97.124  76.708  1.00 319.53 ? 440 ILE B CD1 1 
ATOM   6625  N  N   . LEU B 2 441 ? 77.720  95.661  81.892  1.00 252.29 ? 441 LEU B N   1 
ATOM   6626  C  CA  . LEU B 2 441 ? 76.877  95.767  83.074  1.00 319.06 ? 441 LEU B CA  1 
ATOM   6627  C  C   . LEU B 2 441 ? 77.721  95.558  84.333  1.00 303.08 ? 441 LEU B C   1 
ATOM   6628  O  O   . LEU B 2 441 ? 77.572  96.318  85.296  1.00 351.23 ? 441 LEU B O   1 
ATOM   6629  C  CB  . LEU B 2 441 ? 75.726  94.757  82.964  1.00 395.73 ? 441 LEU B CB  1 
ATOM   6630  C  CG  . LEU B 2 441 ? 74.803  94.634  84.179  1.00 472.79 ? 441 LEU B CG  1 
ATOM   6631  C  CD1 . LEU B 2 441 ? 74.056  95.934  84.451  1.00 493.33 ? 441 LEU B CD1 1 
ATOM   6632  C  CD2 . LEU B 2 441 ? 73.819  93.492  83.980  1.00 508.01 ? 441 LEU B CD2 1 
ATOM   6633  N  N   . ALA B 2 442 ? 78.593  94.539  84.300  1.00 265.82 ? 442 ALA B N   1 
ATOM   6634  C  CA  . ALA B 2 442 ? 79.531  94.250  85.376  1.00 289.84 ? 442 ALA B CA  1 
ATOM   6635  C  C   . ALA B 2 442 ? 80.494  95.425  85.635  1.00 242.00 ? 442 ALA B C   1 
ATOM   6636  O  O   . ALA B 2 442 ? 80.686  95.811  86.787  1.00 248.20 ? 442 ALA B O   1 
ATOM   6637  C  CB  . ALA B 2 442 ? 80.231  92.952  85.042  1.00 286.25 ? 442 ALA B CB  1 
ATOM   6638  N  N   . CYS B 2 443 ? 81.094  96.020  84.593  1.00 207.85 ? 443 CYS B N   1 
ATOM   6639  C  CA  . CYS B 2 443 ? 82.022  97.132  84.782  1.00 249.38 ? 443 CYS B CA  1 
ATOM   6640  C  C   . CYS B 2 443 ? 81.342  98.371  85.369  1.00 223.21 ? 443 CYS B C   1 
ATOM   6641  O  O   . CYS B 2 443 ? 81.919  99.023  86.241  1.00 194.52 ? 443 CYS B O   1 
ATOM   6642  C  CB  . CYS B 2 443 ? 82.721  97.480  83.475  1.00 248.32 ? 443 CYS B CB  1 
ATOM   6643  S  SG  . CYS B 2 443 ? 83.790  96.135  82.918  1.00 254.83 ? 443 CYS B SG  1 
ATOM   6644  N  N   . LEU B 2 444 ? 80.122  98.693  84.922  1.00 238.72 ? 444 LEU B N   1 
ATOM   6645  C  CA  . LEU B 2 444 ? 79.417  99.848  85.471  1.00 287.87 ? 444 LEU B CA  1 
ATOM   6646  C  C   . LEU B 2 444 ? 79.179  99.697  86.985  1.00 272.71 ? 444 LEU B C   1 
ATOM   6647  O  O   . LEU B 2 444 ? 79.098  100.703 87.697  1.00 259.72 ? 444 LEU B O   1 
ATOM   6648  C  CB  . LEU B 2 444 ? 78.125  100.049 84.668  1.00 323.82 ? 444 LEU B CB  1 
ATOM   6649  C  CG  . LEU B 2 444 ? 78.327  100.533 83.225  1.00 280.02 ? 444 LEU B CG  1 
ATOM   6650  C  CD1 . LEU B 2 444 ? 77.013  100.544 82.459  1.00 257.48 ? 444 LEU B CD1 1 
ATOM   6651  C  CD2 . LEU B 2 444 ? 78.954  101.929 83.183  1.00 281.33 ? 444 LEU B CD2 1 
ATOM   6652  N  N   . PHE B 2 445 ? 79.089  98.446  87.468  1.00 239.83 ? 445 PHE B N   1 
ATOM   6653  C  CA  . PHE B 2 445 ? 79.014  98.123  88.889  1.00 255.41 ? 445 PHE B CA  1 
ATOM   6654  C  C   . PHE B 2 445 ? 80.383  98.264  89.563  1.00 221.28 ? 445 PHE B C   1 
ATOM   6655  O  O   . PHE B 2 445 ? 80.466  98.849  90.642  1.00 208.76 ? 445 PHE B O   1 
ATOM   6656  C  CB  . PHE B 2 445 ? 78.396  96.731  89.028  1.00 326.64 ? 445 PHE B CB  1 
ATOM   6657  C  CG  . PHE B 2 445 ? 78.444  96.097  90.389  1.00 378.40 ? 445 PHE B CG  1 
ATOM   6658  C  CD1 . PHE B 2 445 ? 77.497  96.421  91.352  1.00 437.38 ? 445 PHE B CD1 1 
ATOM   6659  C  CD2 . PHE B 2 445 ? 79.430  95.171  90.698  1.00 361.09 ? 445 PHE B CD2 1 
ATOM   6660  C  CE1 . PHE B 2 445 ? 77.536  95.830  92.606  1.00 464.87 ? 445 PHE B CE1 1 
ATOM   6661  C  CE2 . PHE B 2 445 ? 79.465  94.575  91.951  1.00 411.17 ? 445 PHE B CE2 1 
ATOM   6662  C  CZ  . PHE B 2 445 ? 78.517  94.907  92.901  1.00 468.02 ? 445 PHE B CZ  1 
ATOM   6663  N  N   . LEU B 2 446 ? 81.458  97.749  88.945  1.00 217.10 ? 446 LEU B N   1 
ATOM   6664  C  CA  . LEU B 2 446 ? 82.806  97.856  89.511  1.00 204.81 ? 446 LEU B CA  1 
ATOM   6665  C  C   . LEU B 2 446 ? 83.303  99.303  89.566  1.00 172.18 ? 446 LEU B C   1 
ATOM   6666  O  O   . LEU B 2 446 ? 84.016  99.648  90.510  1.00 259.37 ? 446 LEU B O   1 
ATOM   6667  C  CB  . LEU B 2 446 ? 83.798  96.999  88.718  1.00 221.75 ? 446 LEU B CB  1 
ATOM   6668  C  CG  . LEU B 2 446 ? 83.516  95.495  88.684  1.00 271.40 ? 446 LEU B CG  1 
ATOM   6669  C  CD1 . LEU B 2 446 ? 84.553  94.820  87.811  1.00 269.81 ? 446 LEU B CD1 1 
ATOM   6670  C  CD2 . LEU B 2 446 ? 83.486  94.861  90.074  1.00 271.76 ? 446 LEU B CD2 1 
ATOM   6671  N  N   . ILE B 2 447 ? 82.949  100.145 88.585  1.00 186.24 ? 447 ILE B N   1 
ATOM   6672  C  CA  . ILE B 2 447 ? 83.276  101.573 88.618  1.00 253.39 ? 447 ILE B CA  1 
ATOM   6673  C  C   . ILE B 2 447 ? 82.659  102.229 89.865  1.00 233.97 ? 447 ILE B C   1 
ATOM   6674  O  O   . ILE B 2 447 ? 83.315  103.010 90.557  1.00 157.03 ? 447 ILE B O   1 
ATOM   6675  C  CB  . ILE B 2 447 ? 82.862  102.262 87.297  1.00 264.36 ? 447 ILE B CB  1 
ATOM   6676  C  CG1 . ILE B 2 447 ? 83.698  101.745 86.118  1.00 258.17 ? 447 ILE B CG1 1 
ATOM   6677  C  CG2 . ILE B 2 447 ? 82.936  103.787 87.396  1.00 259.74 ? 447 ILE B CG2 1 
ATOM   6678  C  CD1 . ILE B 2 447 ? 83.010  101.879 84.772  1.00 245.41 ? 447 ILE B CD1 1 
ATOM   6679  N  N   . ALA B 2 448 ? 81.401  101.886 90.165  1.00 266.04 ? 448 ALA B N   1 
ATOM   6680  C  CA  . ALA B 2 448 ? 80.737  102.357 91.376  1.00 290.77 ? 448 ALA B CA  1 
ATOM   6681  C  C   . ALA B 2 448 ? 81.429  101.828 92.640  1.00 207.89 ? 448 ALA B C   1 
ATOM   6682  O  O   . ALA B 2 448 ? 81.648  102.613 93.570  1.00 196.05 ? 448 ALA B O   1 
ATOM   6683  C  CB  . ALA B 2 448 ? 79.264  101.994 91.325  1.00 366.57 ? 448 ALA B CB  1 
ATOM   6684  N  N   . VAL B 2 449 ? 81.776  100.523 92.675  1.00 134.96 ? 449 VAL B N   1 
ATOM   6685  C  CA  . VAL B 2 449 ? 82.550  99.940  93.777  1.00 229.58 ? 449 VAL B CA  1 
ATOM   6686  C  C   . VAL B 2 449 ? 83.885  100.668 94.000  1.00 243.11 ? 449 VAL B C   1 
ATOM   6687  O  O   . VAL B 2 449 ? 84.289  100.884 95.145  1.00 183.59 ? 449 VAL B O   1 
ATOM   6688  C  CB  . VAL B 2 449 ? 82.770  98.430  93.555  1.00 252.15 ? 449 VAL B CB  1 
ATOM   6689  C  CG1 . VAL B 2 449 ? 83.867  97.824  94.433  1.00 240.85 ? 449 VAL B CG1 1 
ATOM   6690  C  CG2 . VAL B 2 449 ? 81.459  97.687  93.745  1.00 261.83 ? 449 VAL B CG2 1 
ATOM   6691  N  N   . SER B 2 450 ? 84.560  101.039 92.904  1.00 274.70 ? 450 SER B N   1 
ATOM   6692  C  CA  . SER B 2 450 ? 85.838  101.733 92.953  1.00 264.74 ? 450 SER B CA  1 
ATOM   6693  C  C   . SER B 2 450 ? 85.724  103.083 93.658  1.00 260.42 ? 450 SER B C   1 
ATOM   6694  O  O   . SER B 2 450 ? 86.609  103.411 94.447  1.00 283.01 ? 450 SER B O   1 
ATOM   6695  C  CB  . SER B 2 450 ? 86.382  101.914 91.581  1.00 295.89 ? 450 SER B CB  1 
ATOM   6696  O  OG  . SER B 2 450 ? 86.449  100.660 90.924  1.00 273.71 ? 450 SER B OG  1 
ATOM   6697  N  N   . PHE B 2 451 ? 84.650  103.838 93.373  1.00 199.56 ? 451 PHE B N   1 
ATOM   6698  C  CA  . PHE B 2 451 ? 84.313  105.025 94.141  1.00 209.69 ? 451 PHE B CA  1 
ATOM   6699  C  C   . PHE B 2 451 ? 83.959  104.668 95.591  1.00 231.26 ? 451 PHE B C   1 
ATOM   6700  O  O   . PHE B 2 451 ? 84.532  105.249 96.512  1.00 199.06 ? 451 PHE B O   1 
ATOM   6701  C  CB  . PHE B 2 451 ? 83.183  105.806 93.465  1.00 220.26 ? 451 PHE B CB  1 
ATOM   6702  C  CG  . PHE B 2 451 ? 83.627  106.782 92.403  1.00 317.43 ? 451 PHE B CG  1 
ATOM   6703  C  CD1 . PHE B 2 451 ? 84.014  106.355 91.133  1.00 362.02 ? 451 PHE B CD1 1 
ATOM   6704  C  CD2 . PHE B 2 451 ? 83.659  108.147 92.674  1.00 361.24 ? 451 PHE B CD2 1 
ATOM   6705  C  CE1 . PHE B 2 451 ? 84.419  107.264 90.162  1.00 414.31 ? 451 PHE B CE1 1 
ATOM   6706  C  CE2 . PHE B 2 451 ? 84.064  109.056 91.705  1.00 398.15 ? 451 PHE B CE2 1 
ATOM   6707  C  CZ  . PHE B 2 451 ? 84.441  108.615 90.451  1.00 419.50 ? 451 PHE B CZ  1 
ATOM   6708  N  N   . TRP B 2 452 ? 83.024  103.727 95.806  1.00 243.50 ? 452 TRP B N   1 
ATOM   6709  C  CA  . TRP B 2 452 ? 82.529  103.374 97.142  1.00 249.28 ? 452 TRP B CA  1 
ATOM   6710  C  C   . TRP B 2 452 ? 83.632  102.906 98.111  1.00 247.95 ? 452 TRP B C   1 
ATOM   6711  O  O   . TRP B 2 452 ? 83.496  103.098 99.322  1.00 233.28 ? 452 TRP B O   1 
ATOM   6712  C  CB  . TRP B 2 452 ? 81.417  102.330 96.983  1.00 286.32 ? 452 TRP B CB  1 
ATOM   6713  C  CG  . TRP B 2 452 ? 80.871  101.749 98.262  1.00 280.76 ? 452 TRP B CG  1 
ATOM   6714  C  CD1 . TRP B 2 452 ? 80.143  102.398 99.215  1.00 310.17 ? 452 TRP B CD1 1 
ATOM   6715  C  CD2 . TRP B 2 452 ? 81.011  100.380 98.714  1.00 280.79 ? 452 TRP B CD2 1 
ATOM   6716  N  NE1 . TRP B 2 452 ? 79.821  101.531 100.229 1.00 357.88 ? 452 TRP B NE1 1 
ATOM   6717  C  CE2 . TRP B 2 452 ? 80.335  100.286 99.955  1.00 356.50 ? 452 TRP B CE2 1 
ATOM   6718  C  CE3 . TRP B 2 452 ? 81.631  99.225  98.204  1.00 252.93 ? 452 TRP B CE3 1 
ATOM   6719  C  CZ2 . TRP B 2 452 ? 80.270  99.088  100.679 1.00 358.10 ? 452 TRP B CZ2 1 
ATOM   6720  C  CZ3 . TRP B 2 452 ? 81.572  98.044  98.920  1.00 286.66 ? 452 TRP B CZ3 1 
ATOM   6721  C  CH2 . TRP B 2 452 ? 80.891  97.977  100.141 1.00 311.88 ? 452 TRP B CH2 1 
ATOM   6722  N  N   . LYS B 2 453 ? 84.724  102.309 97.596  1.00 285.58 ? 453 LYS B N   1 
ATOM   6723  C  CA  . LYS B 2 453 ? 85.912  101.977 98.383  1.00 304.68 ? 453 LYS B CA  1 
ATOM   6724  C  C   . LYS B 2 453 ? 86.576  103.216 99.001  1.00 261.86 ? 453 LYS B C   1 
ATOM   6725  O  O   . LYS B 2 453 ? 87.036  103.133 100.137 1.00 185.44 ? 453 LYS B O   1 
ATOM   6726  C  CB  . LYS B 2 453 ? 86.931  101.225 97.516  1.00 353.69 ? 453 LYS B CB  1 
ATOM   6727  C  CG  . LYS B 2 453 ? 88.280  100.943 98.169  1.00 412.16 ? 453 LYS B CG  1 
ATOM   6728  C  CD  . LYS B 2 453 ? 89.230  100.128 97.313  1.00 475.34 ? 453 LYS B CD  1 
ATOM   6729  C  CE  . LYS B 2 453 ? 88.946  98.641  97.298  1.00 496.17 ? 453 LYS B CE  1 
ATOM   6730  N  NZ  . LYS B 2 453 ? 90.127  97.881  96.825  1.00 503.32 ? 453 LYS B NZ  1 
ATOM   6731  N  N   . THR B 2 454 ? 86.640  104.334 98.254  1.00 290.34 ? 454 THR B N   1 
ATOM   6732  C  CA  . THR B 2 454 ? 87.259  105.577 98.720  1.00 323.87 ? 454 THR B CA  1 
ATOM   6733  C  C   . THR B 2 454 ? 86.702  106.760 97.908  1.00 306.55 ? 454 THR B C   1 
ATOM   6734  O  O   . THR B 2 454 ? 87.333  107.247 96.975  1.00 306.96 ? 454 THR B O   1 
ATOM   6735  C  CB  . THR B 2 454 ? 88.798  105.457 98.732  1.00 343.31 ? 454 THR B CB  1 
ATOM   6736  O  OG1 . THR B 2 454 ? 89.345  106.724 99.105  1.00 296.20 ? 454 THR B OG1 1 
ATOM   6737  C  CG2 . THR B 2 454 ? 89.415  105.018 97.418  1.00 365.47 ? 454 THR B CG2 1 
ATOM   6738  N  N   . PRO B 2 455 ? 85.485  107.268 98.233  1.00 325.63 ? 455 PRO B N   1 
ATOM   6739  C  CA  . PRO B 2 455 ? 84.858  108.363 97.476  1.00 350.04 ? 455 PRO B CA  1 
ATOM   6740  C  C   . PRO B 2 455 ? 85.629  109.684 97.351  1.00 290.09 ? 455 PRO B C   1 
ATOM   6741  O  O   . PRO B 2 455 ? 85.280  110.491 96.493  1.00 275.53 ? 455 PRO B O   1 
ATOM   6742  C  CB  . PRO B 2 455 ? 83.543  108.616 98.250  1.00 425.38 ? 455 PRO B CB  1 
ATOM   6743  C  CG  . PRO B 2 455 ? 83.254  107.300 98.929  1.00 436.84 ? 455 PRO B CG  1 
ATOM   6744  C  CD  . PRO B 2 455 ? 84.624  106.802 99.333  1.00 378.69 ? 455 PRO B CD  1 
ATOM   6745  N  N   . VAL B 2 456 ? 86.662  109.898 98.186  1.00 307.67 ? 456 VAL B N   1 
ATOM   6746  C  CA  . VAL B 2 456 ? 87.540  111.060 98.084  1.00 312.12 ? 456 VAL B CA  1 
ATOM   6747  C  C   . VAL B 2 456 ? 88.493  110.896 96.894  1.00 313.36 ? 456 VAL B C   1 
ATOM   6748  O  O   . VAL B 2 456 ? 88.566  111.783 96.043  1.00 320.22 ? 456 VAL B O   1 
ATOM   6749  C  CB  . VAL B 2 456 ? 88.322  111.303 99.396  1.00 321.52 ? 456 VAL B CB  1 
ATOM   6750  C  CG1 . VAL B 2 456 ? 89.246  112.512 99.298  1.00 312.03 ? 456 VAL B CG1 1 
ATOM   6751  C  CG2 . VAL B 2 456 ? 87.397  111.447 100.596 1.00 335.08 ? 456 VAL B CG2 1 
ATOM   6752  N  N   . GLU B 2 457 ? 89.220  109.767 96.833  1.00 311.80 ? 457 GLU B N   1 
ATOM   6753  C  CA  . GLU B 2 457 ? 90.365  109.636 95.936  1.00 299.12 ? 457 GLU B CA  1 
ATOM   6754  C  C   . GLU B 2 457 ? 89.941  109.549 94.464  1.00 303.95 ? 457 GLU B C   1 
ATOM   6755  O  O   . GLU B 2 457 ? 90.605  110.132 93.609  1.00 341.89 ? 457 GLU B O   1 
ATOM   6756  C  CB  . GLU B 2 457 ? 91.214  108.431 96.351  1.00 346.56 ? 457 GLU B CB  1 
ATOM   6757  C  CG  . GLU B 2 457 ? 92.027  108.686 97.608  1.00 330.03 ? 457 GLU B CG  1 
ATOM   6758  C  CD  . GLU B 2 457 ? 93.099  107.652 97.916  1.00 334.04 ? 457 GLU B CD  1 
ATOM   6759  O  OE1 . GLU B 2 457 ? 93.028  106.516 97.376  1.00 379.98 ? 457 GLU B OE1 1 
ATOM   6760  O  OE2 . GLU B 2 457 ? 94.014  107.985 98.695  1.00 320.33 ? 457 GLU B OE2 1 
ATOM   6761  N  N   . CYS B 2 458 ? 88.848  108.838 94.151  1.00 286.14 ? 458 CYS B N   1 
ATOM   6762  C  CA  . CYS B 2 458 ? 88.293  108.823 92.793  1.00 304.68 ? 458 CYS B CA  1 
ATOM   6763  C  C   . CYS B 2 458 ? 87.805  110.224 92.368  1.00 248.74 ? 458 CYS B C   1 
ATOM   6764  O  O   . CYS B 2 458 ? 87.812  110.543 91.183  1.00 256.35 ? 458 CYS B O   1 
ATOM   6765  C  CB  . CYS B 2 458 ? 87.217  107.742 92.682  1.00 315.17 ? 458 CYS B CB  1 
ATOM   6766  S  SG  . CYS B 2 458 ? 87.918  106.102 93.037  1.00 234.06 ? 458 CYS B SG  1 
ATOM   6767  N  N   . GLY B 2 459 ? 87.398  111.068 93.322  1.00 211.28 ? 459 GLY B N   1 
ATOM   6768  C  CA  . GLY B 2 459 ? 87.133  112.476 93.065  1.00 245.66 ? 459 GLY B CA  1 
ATOM   6769  C  C   . GLY B 2 459 ? 88.388  113.282 92.717  1.00 272.00 ? 459 GLY B C   1 
ATOM   6770  O  O   . GLY B 2 459 ? 88.326  114.128 91.832  1.00 334.50 ? 459 GLY B O   1 
ATOM   6771  N  N   . ILE B 2 460 ? 89.519  113.029 93.400  1.00 245.64 ? 460 ILE B N   1 
ATOM   6772  C  CA  . ILE B 2 460 ? 90.787  113.678 93.075  1.00 262.09 ? 460 ILE B CA  1 
ATOM   6773  C  C   . ILE B 2 460 ? 91.183  113.300 91.645  1.00 250.95 ? 460 ILE B C   1 
ATOM   6774  O  O   . ILE B 2 460 ? 91.507  114.186 90.852  1.00 178.20 ? 460 ILE B O   1 
ATOM   6775  C  CB  . ILE B 2 460 ? 91.910  113.344 94.091  1.00 308.90 ? 460 ILE B CB  1 
ATOM   6776  C  CG1 . ILE B 2 460 ? 91.568  113.708 95.545  1.00 322.74 ? 460 ILE B CG1 1 
ATOM   6777  C  CG2 . ILE B 2 460 ? 93.225  113.989 93.656  1.00 326.14 ? 460 ILE B CG2 1 
ATOM   6778  C  CD1 . ILE B 2 460 ? 91.245  115.164 95.799  1.00 355.17 ? 460 ILE B CD1 1 
ATOM   6779  N  N   . GLY B 2 461 ? 91.150  111.995 91.316  1.00 303.84 ? 461 GLY B N   1 
ATOM   6780  C  CA  . GLY B 2 461 ? 91.367  111.510 89.954  1.00 326.81 ? 461 GLY B CA  1 
ATOM   6781  C  C   . GLY B 2 461 ? 90.488  112.216 88.923  1.00 270.38 ? 461 GLY B C   1 
ATOM   6782  O  O   . GLY B 2 461 ? 90.999  112.736 87.940  1.00 267.11 ? 461 GLY B O   1 
ATOM   6783  N  N   . PHE B 2 462 ? 89.176  112.252 89.161  1.00 242.19 ? 462 PHE B N   1 
ATOM   6784  C  CA  . PHE B 2 462 ? 88.230  112.938 88.284  1.00 273.53 ? 462 PHE B CA  1 
ATOM   6785  C  C   . PHE B 2 462 ? 88.571  114.436 88.142  1.00 245.19 ? 462 PHE B C   1 
ATOM   6786  O  O   . PHE B 2 462 ? 88.384  115.000 87.062  1.00 248.01 ? 462 PHE B O   1 
ATOM   6787  C  CB  . PHE B 2 462 ? 86.794  112.708 88.782  1.00 281.83 ? 462 PHE B CB  1 
ATOM   6788  C  CG  . PHE B 2 462 ? 85.721  112.893 87.737  1.00 331.45 ? 462 PHE B CG  1 
ATOM   6789  C  CD1 . PHE B 2 462 ? 85.338  114.163 87.315  1.00 337.40 ? 462 PHE B CD1 1 
ATOM   6790  C  CD2 . PHE B 2 462 ? 85.093  111.789 87.165  1.00 398.90 ? 462 PHE B CD2 1 
ATOM   6791  C  CE1 . PHE B 2 462 ? 84.351  114.323 86.349  1.00 432.24 ? 462 PHE B CE1 1 
ATOM   6792  C  CE2 . PHE B 2 462 ? 84.109  111.951 86.200  1.00 461.39 ? 462 PHE B CE2 1 
ATOM   6793  C  CZ  . PHE B 2 462 ? 83.739  113.217 85.793  1.00 491.40 ? 462 PHE B CZ  1 
ATOM   6794  N  N   . THR B 2 463 ? 89.084  115.084 89.205  1.00 256.67 ? 463 THR B N   1 
ATOM   6795  C  CA  . THR B 2 463 ? 89.562  116.465 89.146  1.00 325.00 ? 463 THR B CA  1 
ATOM   6796  C  C   . THR B 2 463 ? 90.754  116.600 88.192  1.00 300.52 ? 463 THR B C   1 
ATOM   6797  O  O   . THR B 2 463 ? 90.826  117.573 87.444  1.00 312.56 ? 463 THR B O   1 
ATOM   6798  C  CB  . THR B 2 463 ? 89.923  117.006 90.542  1.00 367.59 ? 463 THR B CB  1 
ATOM   6799  O  OG1 . THR B 2 463 ? 88.788  116.814 91.390  1.00 470.20 ? 463 THR B OG1 1 
ATOM   6800  C  CG2 . THR B 2 463 ? 90.336  118.465 90.562  1.00 373.45 ? 463 THR B CG2 1 
ATOM   6801  N  N   . ILE B 2 464 ? 91.686  115.635 88.216  1.00 247.82 ? 464 ILE B N   1 
ATOM   6802  C  CA  . ILE B 2 464 ? 92.863  115.669 87.352  1.00 245.13 ? 464 ILE B CA  1 
ATOM   6803  C  C   . ILE B 2 464 ? 92.478  115.375 85.895  1.00 203.21 ? 464 ILE B C   1 
ATOM   6804  O  O   . ILE B 2 464 ? 93.106  115.931 85.003  1.00 192.99 ? 464 ILE B O   1 
ATOM   6805  C  CB  . ILE B 2 464 ? 93.977  114.729 87.867  1.00 261.40 ? 464 ILE B CB  1 
ATOM   6806  C  CG1 . ILE B 2 464 ? 94.445  115.086 89.287  1.00 268.83 ? 464 ILE B CG1 1 
ATOM   6807  C  CG2 . ILE B 2 464 ? 95.151  114.713 86.886  1.00 287.77 ? 464 ILE B CG2 1 
ATOM   6808  C  CD1 . ILE B 2 464 ? 95.181  113.969 90.011  1.00 233.73 ? 464 ILE B CD1 1 
ATOM   6809  N  N   . ILE B 2 465 ? 91.467  114.537 85.619  1.00 219.11 ? 465 ILE B N   1 
ATOM   6810  C  CA  . ILE B 2 465 ? 90.972  114.330 84.253  1.00 259.74 ? 465 ILE B CA  1 
ATOM   6811  C  C   . ILE B 2 465 ? 90.644  115.679 83.607  1.00 257.70 ? 465 ILE B C   1 
ATOM   6812  O  O   . ILE B 2 465 ? 90.984  115.881 82.442  1.00 218.64 ? 465 ILE B O   1 
ATOM   6813  C  CB  . ILE B 2 465 ? 89.771  113.351 84.203  1.00 285.96 ? 465 ILE B CB  1 
ATOM   6814  C  CG1 . ILE B 2 465 ? 90.200  111.931 84.600  1.00 265.21 ? 465 ILE B CG1 1 
ATOM   6815  C  CG2 . ILE B 2 465 ? 89.069  113.364 82.841  1.00 268.88 ? 465 ILE B CG2 1 
ATOM   6816  C  CD1 . ILE B 2 465 ? 89.076  110.948 84.785  1.00 307.10 ? 465 ILE B CD1 1 
ATOM   6817  N  N   . LEU B 2 466 ? 90.004  116.595 84.354  1.00 268.73 ? 466 LEU B N   1 
ATOM   6818  C  CA  . LEU B 2 466 ? 89.626  117.895 83.812  1.00 320.59 ? 466 LEU B CA  1 
ATOM   6819  C  C   . LEU B 2 466 ? 90.850  118.764 83.471  1.00 310.24 ? 466 LEU B C   1 
ATOM   6820  O  O   . LEU B 2 466 ? 90.690  119.699 82.699  1.00 318.83 ? 466 LEU B O   1 
ATOM   6821  C  CB  . LEU B 2 466 ? 88.685  118.612 84.791  1.00 398.19 ? 466 LEU B CB  1 
ATOM   6822  C  CG  . LEU B 2 466 ? 87.363  117.916 85.146  1.00 446.93 ? 466 LEU B CG  1 
ATOM   6823  C  CD1 . LEU B 2 466 ? 86.446  118.879 85.885  1.00 508.27 ? 466 LEU B CD1 1 
ATOM   6824  C  CD2 . LEU B 2 466 ? 86.626  117.323 83.945  1.00 434.17 ? 466 LEU B CD2 1 
ATOM   6825  N  N   . SER B 2 467 ? 92.059  118.481 84.000  1.00 284.60 ? 467 SER B N   1 
ATOM   6826  C  CA  . SER B 2 467 ? 93.307  119.086 83.521  1.00 284.25 ? 467 SER B CA  1 
ATOM   6827  C  C   . SER B 2 467 ? 93.539  118.863 82.017  1.00 250.93 ? 467 SER B C   1 
ATOM   6828  O  O   . SER B 2 467 ? 94.274  119.614 81.376  1.00 237.09 ? 467 SER B O   1 
ATOM   6829  C  CB  . SER B 2 467 ? 94.505  118.599 84.342  1.00 238.22 ? 467 SER B CB  1 
ATOM   6830  O  OG  . SER B 2 467 ? 95.704  119.277 84.018  1.00 192.82 ? 467 SER B OG  1 
ATOM   6831  N  N   . GLY B 2 468 ? 92.925  117.830 81.432  1.00 269.91 ? 468 GLY B N   1 
ATOM   6832  C  CA  . GLY B 2 468 ? 92.951  117.620 79.995  1.00 307.67 ? 468 GLY B CA  1 
ATOM   6833  C  C   . GLY B 2 468 ? 92.245  118.694 79.174  1.00 301.01 ? 468 GLY B C   1 
ATOM   6834  O  O   . GLY B 2 468 ? 92.601  118.900 78.022  1.00 299.84 ? 468 GLY B O   1 
ATOM   6835  N  N   . LEU B 2 469 ? 91.239  119.369 79.739  1.00 276.71 ? 469 LEU B N   1 
ATOM   6836  C  CA  . LEU B 2 469 ? 90.469  120.337 78.970  1.00 249.62 ? 469 LEU B CA  1 
ATOM   6837  C  C   . LEU B 2 469 ? 91.318  121.574 78.650  1.00 216.12 ? 469 LEU B C   1 
ATOM   6838  O  O   . LEU B 2 469 ? 91.356  121.938 77.477  1.00 224.57 ? 469 LEU B O   1 
ATOM   6839  C  CB  . LEU B 2 469 ? 89.164  120.650 79.716  1.00 268.40 ? 469 LEU B CB  1 
ATOM   6840  C  CG  . LEU B 2 469 ? 88.169  119.483 79.797  1.00 261.90 ? 469 LEU B CG  1 
ATOM   6841  C  CD1 . LEU B 2 469 ? 86.989  119.830 80.688  1.00 321.87 ? 469 LEU B CD1 1 
ATOM   6842  C  CD2 . LEU B 2 469 ? 87.664  119.082 78.416  1.00 191.64 ? 469 LEU B CD2 1 
ATOM   6843  N  N   . PRO B 2 470 ? 92.021  122.262 79.599  1.00 264.58 ? 470 PRO B N   1 
ATOM   6844  C  CA  . PRO B 2 470 ? 93.016  123.287 79.246  1.00 316.76 ? 470 PRO B CA  1 
ATOM   6845  C  C   . PRO B 2 470 ? 93.947  122.887 78.106  1.00 279.18 ? 470 PRO B C   1 
ATOM   6846  O  O   . PRO B 2 470 ? 94.134  123.666 77.173  1.00 283.31 ? 470 PRO B O   1 
ATOM   6847  C  CB  . PRO B 2 470 ? 93.826  123.518 80.540  1.00 280.50 ? 470 PRO B CB  1 
ATOM   6848  C  CG  . PRO B 2 470 ? 92.800  123.252 81.629  1.00 296.71 ? 470 PRO B CG  1 
ATOM   6849  C  CD  . PRO B 2 470 ? 91.904  122.156 81.062  1.00 275.52 ? 470 PRO B CD  1 
ATOM   6850  N  N   . VAL B 2 471 ? 94.507  121.672 78.188  1.00 247.43 ? 471 VAL B N   1 
ATOM   6851  C  CA  . VAL B 2 471 ? 95.529  121.257 77.241  1.00 254.79 ? 471 VAL B CA  1 
ATOM   6852  C  C   . VAL B 2 471 ? 94.884  120.986 75.881  1.00 263.67 ? 471 VAL B C   1 
ATOM   6853  O  O   . VAL B 2 471 ? 95.491  121.338 74.875  1.00 363.86 ? 471 VAL B O   1 
ATOM   6854  C  CB  . VAL B 2 471 ? 96.355  120.068 77.766  1.00 255.79 ? 471 VAL B CB  1 
ATOM   6855  C  CG1 . VAL B 2 471 ? 97.449  119.638 76.795  1.00 290.24 ? 471 VAL B CG1 1 
ATOM   6856  C  CG2 . VAL B 2 471 ? 96.968  120.418 79.107  1.00 289.33 ? 471 VAL B CG2 1 
ATOM   6857  N  N   . TYR B 2 472 ? 93.687  120.380 75.830  1.00 200.19 ? 472 TYR B N   1 
ATOM   6858  C  CA  . TYR B 2 472 ? 93.004  120.136 74.562  1.00 239.15 ? 472 TYR B CA  1 
ATOM   6859  C  C   . TYR B 2 472 ? 92.689  121.448 73.833  1.00 222.47 ? 472 TYR B C   1 
ATOM   6860  O  O   . TYR B 2 472 ? 92.947  121.586 72.638  1.00 179.08 ? 472 TYR B O   1 
ATOM   6861  C  CB  . TYR B 2 472 ? 91.735  119.307 74.772  1.00 207.51 ? 472 TYR B CB  1 
ATOM   6862  C  CG  . TYR B 2 472 ? 91.063  119.005 73.441  1.00 216.77 ? 472 TYR B CG  1 
ATOM   6863  C  CD1 . TYR B 2 472 ? 91.523  117.976 72.615  1.00 220.27 ? 472 TYR B CD1 1 
ATOM   6864  C  CD2 . TYR B 2 472 ? 89.986  119.758 72.998  1.00 254.48 ? 472 TYR B CD2 1 
ATOM   6865  C  CE1 . TYR B 2 472 ? 90.922  117.689 71.399  1.00 187.54 ? 472 TYR B CE1 1 
ATOM   6866  C  CE2 . TYR B 2 472 ? 89.377  119.475 71.780  1.00 279.15 ? 472 TYR B CE2 1 
ATOM   6867  C  CZ  . TYR B 2 472 ? 89.844  118.441 70.980  1.00 198.10 ? 472 TYR B CZ  1 
ATOM   6868  O  OH  . TYR B 2 472 ? 89.223  118.194 69.791  1.00 177.57 ? 472 TYR B OH  1 
ATOM   6869  N  N   . PHE B 2 473 ? 92.134  122.426 74.548  1.00 253.61 ? 473 PHE B N   1 
ATOM   6870  C  CA  . PHE B 2 473 ? 91.778  123.692 73.919  1.00 320.07 ? 473 PHE B CA  1 
ATOM   6871  C  C   . PHE B 2 473 ? 93.028  124.455 73.453  1.00 317.56 ? 473 PHE B C   1 
ATOM   6872  O  O   . PHE B 2 473 ? 93.014  125.002 72.352  1.00 351.54 ? 473 PHE B O   1 
ATOM   6873  C  CB  . PHE B 2 473 ? 90.856  124.496 74.844  1.00 362.03 ? 473 PHE B CB  1 
ATOM   6874  C  CG  . PHE B 2 473 ? 89.505  123.862 75.100  1.00 379.37 ? 473 PHE B CG  1 
ATOM   6875  C  CD1 . PHE B 2 473 ? 88.721  123.369 74.053  1.00 341.59 ? 473 PHE B CD1 1 
ATOM   6876  C  CD2 . PHE B 2 473 ? 89.004  123.756 76.394  1.00 391.99 ? 473 PHE B CD2 1 
ATOM   6877  C  CE1 . PHE B 2 473 ? 87.478  122.793 74.292  1.00 303.87 ? 473 PHE B CE1 1 
ATOM   6878  C  CE2 . PHE B 2 473 ? 87.761  123.179 76.631  1.00 369.70 ? 473 PHE B CE2 1 
ATOM   6879  C  CZ  . PHE B 2 473 ? 86.998  122.699 75.581  1.00 310.45 ? 473 PHE B CZ  1 
ATOM   6880  N  N   . PHE B 2 474 ? 94.101  124.489 74.261  1.00 288.74 ? 474 PHE B N   1 
ATOM   6881  C  CA  . PHE B 2 474 ? 95.361  125.124 73.875  1.00 327.40 ? 474 PHE B CA  1 
ATOM   6882  C  C   . PHE B 2 474 ? 96.077  124.375 72.739  1.00 274.04 ? 474 PHE B C   1 
ATOM   6883  O  O   . PHE B 2 474 ? 96.693  125.007 71.883  1.00 259.24 ? 474 PHE B O   1 
ATOM   6884  C  CB  . PHE B 2 474 ? 96.291  125.242 75.090  1.00 340.51 ? 474 PHE B CB  1 
ATOM   6885  C  CG  . PHE B 2 474 ? 97.673  125.772 74.794  1.00 323.45 ? 474 PHE B CG  1 
ATOM   6886  C  CD1 . PHE B 2 474 ? 97.900  127.137 74.661  1.00 358.73 ? 474 PHE B CD1 1 
ATOM   6887  C  CD2 . PHE B 2 474 ? 98.748  124.909 74.632  1.00 272.70 ? 474 PHE B CD2 1 
ATOM   6888  C  CE1 . PHE B 2 474 ? 99.173  127.630 74.385  1.00 359.61 ? 474 PHE B CE1 1 
ATOM   6889  C  CE2 . PHE B 2 474 ? 100.020 125.400 74.356  1.00 299.51 ? 474 PHE B CE2 1 
ATOM   6890  C  CZ  . PHE B 2 474 ? 100.233 126.761 74.231  1.00 337.10 ? 474 PHE B CZ  1 
ATOM   6891  N  N   . GLY B 2 475 ? 96.012  123.038 72.737  1.00 246.85 ? 475 GLY B N   1 
ATOM   6892  C  CA  . GLY B 2 475 ? 96.800  122.203 71.845  1.00 245.24 ? 475 GLY B CA  1 
ATOM   6893  C  C   . GLY B 2 475 ? 96.080  121.789 70.566  1.00 260.56 ? 475 GLY B C   1 
ATOM   6894  O  O   . GLY B 2 475 ? 96.765  121.409 69.615  1.00 344.00 ? 475 GLY B O   1 
ATOM   6895  N  N   . VAL B 2 476 ? 94.729  121.841 70.538  1.00 227.26 ? 476 VAL B N   1 
ATOM   6896  C  CA  . VAL B 2 476 ? 93.954  121.346 69.393  1.00 322.61 ? 476 VAL B CA  1 
ATOM   6897  C  C   . VAL B 2 476 ? 92.993  122.423 68.858  1.00 389.51 ? 476 VAL B C   1 
ATOM   6898  O  O   . VAL B 2 476 ? 92.988  122.691 67.653  1.00 387.70 ? 476 VAL B O   1 
ATOM   6899  C  CB  . VAL B 2 476 ? 93.225  120.022 69.728  1.00 258.08 ? 476 VAL B CB  1 
ATOM   6900  C  CG1 . VAL B 2 476 ? 92.512  119.442 68.510  1.00 308.90 ? 476 VAL B CG1 1 
ATOM   6901  C  CG2 . VAL B 2 476 ? 94.176  118.986 70.315  1.00 213.74 ? 476 VAL B CG2 1 
ATOM   6902  N  N   . TRP B 2 477 ? 92.180  123.036 69.732  1.00 390.16 ? 477 TRP B N   1 
ATOM   6903  C  CA  . TRP B 2 477 ? 91.156  123.985 69.306  1.00 358.56 ? 477 TRP B CA  1 
ATOM   6904  C  C   . TRP B 2 477 ? 91.723  125.362 68.926  1.00 340.05 ? 477 TRP B C   1 
ATOM   6905  O  O   . TRP B 2 477 ? 91.136  126.043 68.085  1.00 277.96 ? 477 TRP B O   1 
ATOM   6906  C  CB  . TRP B 2 477 ? 90.087  124.108 70.401  1.00 340.59 ? 477 TRP B CB  1 
ATOM   6907  C  CG  . TRP B 2 477 ? 88.900  124.936 69.992  1.00 367.35 ? 477 TRP B CG  1 
ATOM   6908  C  CD1 . TRP B 2 477 ? 88.511  126.117 70.549  1.00 376.16 ? 477 TRP B CD1 1 
ATOM   6909  C  CD2 . TRP B 2 477 ? 87.953  124.645 68.935  1.00 399.35 ? 477 TRP B CD2 1 
ATOM   6910  N  NE1 . TRP B 2 477 ? 87.387  126.584 69.919  1.00 430.49 ? 477 TRP B NE1 1 
ATOM   6911  C  CE2 . TRP B 2 477 ? 87.018  125.708 68.927  1.00 445.17 ? 477 TRP B CE2 1 
ATOM   6912  C  CE3 . TRP B 2 477 ? 87.795  123.604 68.002  1.00 365.15 ? 477 TRP B CE3 1 
ATOM   6913  C  CZ2 . TRP B 2 477 ? 85.951  125.750 68.021  1.00 445.93 ? 477 TRP B CZ2 1 
ATOM   6914  C  CZ3 . TRP B 2 477 ? 86.740  123.647 67.111  1.00 370.67 ? 477 TRP B CZ3 1 
ATOM   6915  C  CH2 . TRP B 2 477 ? 85.831  124.709 67.121  1.00 387.23 ? 477 TRP B CH2 1 
ATOM   6916  N  N   . TRP B 2 478 ? 92.852  125.773 69.527  1.00 363.20 ? 478 TRP B N   1 
ATOM   6917  C  CA  . TRP B 2 478 ? 93.452  127.090 69.310  1.00 356.68 ? 478 TRP B CA  1 
ATOM   6918  C  C   . TRP B 2 478 ? 94.279  127.185 68.014  1.00 373.40 ? 478 TRP B C   1 
ATOM   6919  O  O   . TRP B 2 478 ? 94.639  128.290 67.612  1.00 345.36 ? 478 TRP B O   1 
ATOM   6920  C  CB  . TRP B 2 478 ? 94.294  127.423 70.554  1.00 342.15 ? 478 TRP B CB  1 
ATOM   6921  C  CG  . TRP B 2 478 ? 95.058  128.725 70.556  1.00 310.59 ? 478 TRP B CG  1 
ATOM   6922  C  CD1 . TRP B 2 478 ? 96.400  128.839 70.769  1.00 286.94 ? 478 TRP B CD1 1 
ATOM   6923  C  CD2 . TRP B 2 478 ? 94.565  130.072 70.359  1.00 350.28 ? 478 TRP B CD2 1 
ATOM   6924  N  NE1 . TRP B 2 478 ? 96.781  130.149 70.717  1.00 267.08 ? 478 TRP B NE1 1 
ATOM   6925  C  CE2 . TRP B 2 478 ? 95.686  130.934 70.467  1.00 340.83 ? 478 TRP B CE2 1 
ATOM   6926  C  CE3 . TRP B 2 478 ? 93.303  130.634 70.103  1.00 386.26 ? 478 TRP B CE3 1 
ATOM   6927  C  CZ2 . TRP B 2 478 ? 95.578  132.321 70.326  1.00 408.55 ? 478 TRP B CZ2 1 
ATOM   6928  C  CZ3 . TRP B 2 478 ? 93.194  132.005 69.967  1.00 401.83 ? 478 TRP B CZ3 1 
ATOM   6929  C  CH2 . TRP B 2 478 ? 94.318  132.834 70.078  1.00 430.73 ? 478 TRP B CH2 1 
ATOM   6930  N  N   . LYS B 2 479 ? 94.598  126.045 67.364  1.00 366.65 ? 479 LYS B N   1 
ATOM   6931  C  CA  . LYS B 2 479 ? 95.420  125.938 66.149  1.00 330.20 ? 479 LYS B CA  1 
ATOM   6932  C  C   . LYS B 2 479 ? 96.811  126.601 66.280  1.00 369.89 ? 479 LYS B C   1 
ATOM   6933  O  O   . LYS B 2 479 ? 97.427  126.919 65.258  1.00 326.68 ? 479 LYS B O   1 
ATOM   6934  C  CB  . LYS B 2 479 ? 94.645  126.444 64.915  1.00 333.25 ? 479 LYS B CB  1 
ATOM   6935  C  CG  . LYS B 2 479 ? 93.637  125.474 64.299  1.00 353.67 ? 479 LYS B CG  1 
ATOM   6936  C  CD  . LYS B 2 479 ? 92.289  125.398 64.989  1.00 407.23 ? 479 LYS B CD  1 
ATOM   6937  C  CE  . LYS B 2 479 ? 91.467  126.668 64.878  1.00 449.31 ? 479 LYS B CE  1 
ATOM   6938  N  NZ  . LYS B 2 479 ? 90.123  126.519 65.486  1.00 451.97 ? 479 LYS B NZ  1 
ATOM   6939  N  N   . ASN B 2 480 ? 97.319  126.786 67.518  1.00 443.71 ? 480 ASN B N   1 
ATOM   6940  C  CA  . ASN B 2 480 ? 98.672  127.250 67.827  1.00 490.45 ? 480 ASN B CA  1 
ATOM   6941  C  C   . ASN B 2 480 ? 99.028  128.592 67.151  1.00 426.27 ? 480 ASN B C   1 
ATOM   6942  O  O   . ASN B 2 480 ? 100.187 128.816 66.783  1.00 365.07 ? 480 ASN B O   1 
ATOM   6943  C  CB  . ASN B 2 480 ? 99.681  126.124 67.522  1.00 551.53 ? 480 ASN B CB  1 
ATOM   6944  C  CG  . ASN B 2 480 ? 99.344  124.787 68.166  1.00 489.96 ? 480 ASN B CG  1 
ATOM   6945  O  OD1 . ASN B 2 480 ? 98.946  124.735 69.327  1.00 380.27 ? 480 ASN B OD1 1 
ATOM   6946  N  ND2 . ASN B 2 480 ? 99.501  123.694 67.431  1.00 441.09 ? 480 ASN B ND2 1 
ATOM   6947  N  N   . LYS B 2 481 ? 98.043  129.503 67.026  1.00 388.88 ? 481 LYS B N   1 
ATOM   6948  C  CA  . LYS B 2 481 ? 98.092  130.653 66.111  1.00 363.39 ? 481 LYS B CA  1 
ATOM   6949  C  C   . LYS B 2 481 ? 99.259  131.640 66.330  1.00 382.58 ? 481 LYS B C   1 
ATOM   6950  O  O   . LYS B 2 481 ? 99.826  132.098 65.333  1.00 319.39 ? 481 LYS B O   1 
ATOM   6951  C  CB  . LYS B 2 481 ? 96.750  131.398 66.161  1.00 284.77 ? 481 LYS B CB  1 
ATOM   6952  C  CG  . LYS B 2 481 ? 95.650  130.684 65.393  1.00 315.20 ? 481 LYS B CG  1 
ATOM   6953  C  CD  . LYS B 2 481 ? 94.263  131.246 65.581  1.00 338.13 ? 481 LYS B CD  1 
ATOM   6954  C  CE  . LYS B 2 481 ? 93.174  130.504 64.820  1.00 316.42 ? 481 LYS B CE  1 
ATOM   6955  N  NZ  . LYS B 2 481 ? 93.314  130.549 63.343  1.00 282.83 ? 481 LYS B NZ  1 
ATOM   6956  N  N   . PRO B 2 482 ? 99.658  132.036 67.574  1.00 422.73 ? 482 PRO B N   1 
ATOM   6957  C  CA  . PRO B 2 482 ? 100.768 132.981 67.785  1.00 386.85 ? 482 PRO B CA  1 
ATOM   6958  C  C   . PRO B 2 482 ? 102.103 132.547 67.170  1.00 327.57 ? 482 PRO B C   1 
ATOM   6959  O  O   . PRO B 2 482 ? 102.624 131.486 67.496  1.00 315.31 ? 482 PRO B O   1 
ATOM   6960  C  CB  . PRO B 2 482 ? 100.902 133.068 69.322  1.00 400.01 ? 482 PRO B CB  1 
ATOM   6961  C  CG  . PRO B 2 482 ? 99.534  132.682 69.833  1.00 430.45 ? 482 PRO B CG  1 
ATOM   6962  C  CD  . PRO B 2 482 ? 99.057  131.628 68.854  1.00 455.57 ? 482 PRO B CD  1 
ATOM   6963  N  N   . LYS B 2 483 ? 102.660 133.386 66.285  1.00 332.85 ? 483 LYS B N   1 
ATOM   6964  C  CA  . LYS B 2 483 ? 103.845 133.032 65.509  1.00 358.19 ? 483 LYS B CA  1 
ATOM   6965  C  C   . LYS B 2 483 ? 105.069 132.763 66.403  1.00 337.20 ? 483 LYS B C   1 
ATOM   6966  O  O   . LYS B 2 483 ? 105.911 131.940 66.031  1.00 262.14 ? 483 LYS B O   1 
ATOM   6967  C  CB  . LYS B 2 483 ? 104.127 134.126 64.469  1.00 392.22 ? 483 LYS B CB  1 
ATOM   6968  C  CG  . LYS B 2 483 ? 105.258 133.842 63.484  1.00 408.79 ? 483 LYS B CG  1 
ATOM   6969  C  CD  . LYS B 2 483 ? 105.067 132.580 62.656  1.00 444.70 ? 483 LYS B CD  1 
ATOM   6970  C  CE  . LYS B 2 483 ? 106.141 132.367 61.609  1.00 477.01 ? 483 LYS B CE  1 
ATOM   6971  N  NZ  . LYS B 2 483 ? 106.026 133.326 60.484  1.00 509.90 ? 483 LYS B NZ  1 
ATOM   6972  N  N   . TRP B 2 484 ? 105.166 133.423 67.573  1.00 371.40 ? 484 TRP B N   1 
ATOM   6973  C  CA  . TRP B 2 484 ? 106.242 133.164 68.531  1.00 390.45 ? 484 TRP B CA  1 
ATOM   6974  C  C   . TRP B 2 484 ? 106.143 131.790 69.214  1.00 432.52 ? 484 TRP B C   1 
ATOM   6975  O  O   . TRP B 2 484 ? 107.158 131.319 69.738  1.00 370.73 ? 484 TRP B O   1 
ATOM   6976  C  CB  . TRP B 2 484 ? 106.318 134.293 69.574  1.00 386.04 ? 484 TRP B CB  1 
ATOM   6977  C  CG  . TRP B 2 484 ? 105.116 134.451 70.475  1.00 428.71 ? 484 TRP B CG  1 
ATOM   6978  C  CD1 . TRP B 2 484 ? 104.857 133.758 71.622  1.00 411.75 ? 484 TRP B CD1 1 
ATOM   6979  C  CD2 . TRP B 2 484 ? 104.005 135.367 70.304  1.00 467.65 ? 484 TRP B CD2 1 
ATOM   6980  N  NE1 . TRP B 2 484 ? 103.673 134.173 72.175  1.00 410.41 ? 484 TRP B NE1 1 
ATOM   6981  C  CE2 . TRP B 2 484 ? 103.123 135.158 71.394  1.00 418.11 ? 484 TRP B CE2 1 
ATOM   6982  C  CE3 . TRP B 2 484 ? 103.665 136.339 69.346  1.00 493.66 ? 484 TRP B CE3 1 
ATOM   6983  C  CZ2 . TRP B 2 484 ? 101.934 135.884 71.543  1.00 397.07 ? 484 TRP B CZ2 1 
ATOM   6984  C  CZ3 . TRP B 2 484 ? 102.491 137.056 69.495  1.00 455.14 ? 484 TRP B CZ3 1 
ATOM   6985  C  CH2 . TRP B 2 484 ? 101.638 136.830 70.581  1.00 424.05 ? 484 TRP B CH2 1 
ATOM   6986  N  N   . LEU B 2 485 ? 104.953 131.158 69.222  1.00 467.01 ? 485 LEU B N   1 
ATOM   6987  C  CA  . LEU B 2 485 ? 104.822 129.741 69.557  1.00 427.60 ? 485 LEU B CA  1 
ATOM   6988  C  C   . LEU B 2 485 ? 105.107 128.879 68.322  1.00 357.30 ? 485 LEU B C   1 
ATOM   6989  O  O   . LEU B 2 485 ? 105.945 127.986 68.395  1.00 343.67 ? 485 LEU B O   1 
ATOM   6990  C  CB  . LEU B 2 485 ? 103.421 129.445 70.109  1.00 453.36 ? 485 LEU B CB  1 
ATOM   6991  C  CG  . LEU B 2 485 ? 103.036 130.125 71.424  1.00 517.99 ? 485 LEU B CG  1 
ATOM   6992  C  CD1 . LEU B 2 485 ? 101.624 129.714 71.847  1.00 502.99 ? 485 LEU B CD1 1 
ATOM   6993  C  CD2 . LEU B 2 485 ? 104.021 129.799 72.539  1.00 567.48 ? 485 LEU B CD2 1 
ATOM   6994  N  N   . LEU B 2 486 ? 104.423 129.149 67.199  1.00 323.92 ? 486 LEU B N   1 
ATOM   6995  C  CA  . LEU B 2 486 ? 104.430 128.281 66.020  1.00 313.63 ? 486 LEU B CA  1 
ATOM   6996  C  C   . LEU B 2 486 ? 105.839 128.089 65.430  1.00 299.35 ? 486 LEU B C   1 
ATOM   6997  O  O   . LEU B 2 486 ? 106.206 126.966 65.070  1.00 268.69 ? 486 LEU B O   1 
ATOM   6998  C  CB  . LEU B 2 486 ? 103.454 128.871 64.992  1.00 337.98 ? 486 LEU B CB  1 
ATOM   6999  C  CG  . LEU B 2 486 ? 103.164 128.031 63.750  1.00 326.72 ? 486 LEU B CG  1 
ATOM   7000  C  CD1 . LEU B 2 486 ? 102.412 126.765 64.101  1.00 324.03 ? 486 LEU B CD1 1 
ATOM   7001  C  CD2 . LEU B 2 486 ? 102.351 128.829 62.745  1.00 334.80 ? 486 LEU B CD2 1 
ATOM   7002  N  N   . GLN B 2 487 ? 106.630 129.168 65.340  1.00 324.65 ? 487 GLN B N   1 
ATOM   7003  C  CA  . GLN B 2 487 ? 107.998 129.109 64.823  1.00 350.74 ? 487 GLN B CA  1 
ATOM   7004  C  C   . GLN B 2 487 ? 108.928 128.371 65.801  1.00 353.58 ? 487 GLN B C   1 
ATOM   7005  O  O   . GLN B 2 487 ? 109.855 127.673 65.364  1.00 407.02 ? 487 GLN B O   1 
ATOM   7006  C  CB  . GLN B 2 487 ? 108.475 130.534 64.506  1.00 400.58 ? 487 GLN B CB  1 
ATOM   7007  C  CG  . GLN B 2 487 ? 109.722 130.609 63.623  1.00 447.72 ? 487 GLN B CG  1 
ATOM   7008  C  CD  . GLN B 2 487 ? 111.052 130.470 64.334  1.00 450.98 ? 487 GLN B CD  1 
ATOM   7009  O  OE1 . GLN B 2 487 ? 111.142 130.470 65.561  1.00 402.87 ? 487 GLN B OE1 1 
ATOM   7010  N  NE2 . GLN B 2 487 ? 112.118 130.352 63.557  1.00 433.66 ? 487 GLN B NE2 1 
ATOM   7011  N  N   . GLY B 2 488 ? 108.697 128.531 67.120  1.00 328.54 ? 488 GLY B N   1 
ATOM   7012  C  CA  . GLY B 2 488 ? 109.460 127.836 68.152  1.00 309.70 ? 488 GLY B CA  1 
ATOM   7013  C  C   . GLY B 2 488 ? 109.196 126.328 68.186  1.00 309.11 ? 488 GLY B C   1 
ATOM   7014  O  O   . GLY B 2 488 ? 110.139 125.556 68.364  1.00 215.96 ? 488 GLY B O   1 
ATOM   7015  N  N   . ILE B 2 489 ? 107.913 125.936 68.024  1.00 352.45 ? 489 ILE B N   1 
ATOM   7016  C  CA  . ILE B 2 489 ? 107.474 124.549 67.857  1.00 340.84 ? 489 ILE B CA  1 
ATOM   7017  C  C   . ILE B 2 489 ? 108.246 123.921 66.695  1.00 283.35 ? 489 ILE B C   1 
ATOM   7018  O  O   . ILE B 2 489 ? 108.827 122.845 66.866  1.00 181.13 ? 489 ILE B O   1 
ATOM   7019  C  CB  . ILE B 2 489 ? 105.930 124.472 67.688  1.00 338.44 ? 489 ILE B CB  1 
ATOM   7020  C  CG1 . ILE B 2 489 ? 105.225 124.802 69.012  1.00 336.81 ? 489 ILE B CG1 1 
ATOM   7021  C  CG2 . ILE B 2 489 ? 105.441 123.132 67.126  1.00 306.28 ? 489 ILE B CG2 1 
ATOM   7022  C  CD1 . ILE B 2 489 ? 103.780 125.225 68.878  1.00 333.08 ? 489 ILE B CD1 1 
ATOM   7023  N  N   . PHE B 2 490 ? 108.246 124.602 65.537  1.00 281.20 ? 490 PHE B N   1 
ATOM   7024  C  CA  . PHE B 2 490 ? 108.922 124.105 64.351  1.00 286.64 ? 490 PHE B CA  1 
ATOM   7025  C  C   . PHE B 2 490 ? 110.428 123.983 64.614  1.00 255.22 ? 490 PHE B C   1 
ATOM   7026  O  O   . PHE B 2 490 ? 111.004 122.922 64.370  1.00 260.16 ? 490 PHE B O   1 
ATOM   7027  C  CB  . PHE B 2 490 ? 108.603 124.972 63.128  1.00 306.08 ? 490 PHE B CB  1 
ATOM   7028  C  CG  . PHE B 2 490 ? 109.187 124.412 61.855  1.00 356.12 ? 490 PHE B CG  1 
ATOM   7029  C  CD1 . PHE B 2 490 ? 108.586 123.343 61.192  1.00 378.01 ? 490 PHE B CD1 1 
ATOM   7030  C  CD2 . PHE B 2 490 ? 110.359 124.939 61.328  1.00 369.24 ? 490 PHE B CD2 1 
ATOM   7031  C  CE1 . PHE B 2 490 ? 109.137 122.826 60.027  1.00 347.80 ? 490 PHE B CE1 1 
ATOM   7032  C  CE2 . PHE B 2 490 ? 110.906 124.420 60.162  1.00 402.12 ? 490 PHE B CE2 1 
ATOM   7033  C  CZ  . PHE B 2 490 ? 110.295 123.366 59.512  1.00 376.27 ? 490 PHE B CZ  1 
ATOM   7034  N  N   . SER B 2 491 ? 111.052 125.052 65.132  1.00 287.27 ? 491 SER B N   1 
ATOM   7035  C  CA  . SER B 2 491 ? 112.487 125.069 65.405  1.00 320.06 ? 491 SER B CA  1 
ATOM   7036  C  C   . SER B 2 491 ? 112.916 123.919 66.331  1.00 275.48 ? 491 SER B C   1 
ATOM   7037  O  O   . SER B 2 491 ? 113.948 123.281 66.099  1.00 245.59 ? 491 SER B O   1 
ATOM   7038  C  CB  . SER B 2 491 ? 112.898 126.413 65.969  1.00 404.43 ? 491 SER B CB  1 
ATOM   7039  O  OG  . SER B 2 491 ? 112.602 127.466 65.060  1.00 448.80 ? 491 SER B OG  1 
ATOM   7040  N  N   . THR B 2 492 ? 112.121 123.646 67.377  1.00 281.87 ? 492 THR B N   1 
ATOM   7041  C  CA  . THR B 2 492 ? 112.381 122.547 68.300  1.00 279.94 ? 492 THR B CA  1 
ATOM   7042  C  C   . THR B 2 492 ? 112.202 121.194 67.605  1.00 195.95 ? 492 THR B C   1 
ATOM   7043  O  O   . THR B 2 492 ? 112.981 120.265 67.857  1.00 168.77 ? 492 THR B O   1 
ATOM   7044  C  CB  . THR B 2 492 ? 111.480 122.671 69.541  1.00 364.91 ? 492 THR B CB  1 
ATOM   7045  O  OG1 . THR B 2 492 ? 111.668 123.967 70.118  1.00 321.61 ? 492 THR B OG1 1 
ATOM   7046  C  CG2 . THR B 2 492 ? 111.748 121.629 70.606  1.00 430.86 ? 492 THR B CG2 1 
ATOM   7047  N  N   . THR B 2 493 ? 111.172 121.076 66.751  1.00 179.55 ? 493 THR B N   1 
ATOM   7048  C  CA  . THR B 2 493 ? 110.889 119.844 66.019  1.00 229.31 ? 493 THR B CA  1 
ATOM   7049  C  C   . THR B 2 493 ? 112.072 119.491 65.112  1.00 201.67 ? 493 THR B C   1 
ATOM   7050  O  O   . THR B 2 493 ? 112.560 118.361 65.182  1.00 116.58 ? 493 THR B O   1 
ATOM   7051  C  CB  . THR B 2 493 ? 109.575 119.956 65.224  1.00 297.85 ? 493 THR B CB  1 
ATOM   7052  O  OG1 . THR B 2 493 ? 108.507 120.112 66.158  1.00 339.45 ? 493 THR B OG1 1 
ATOM   7053  C  CG2 . THR B 2 493 ? 109.256 118.764 64.344  1.00 276.87 ? 493 THR B CG2 1 
ATOM   7054  N  N   . VAL B 2 494 ? 112.514 120.453 64.278  1.00 247.86 ? 494 VAL B N   1 
ATOM   7055  C  CA  . VAL B 2 494 ? 113.573 120.205 63.301  1.00 272.23 ? 494 VAL B CA  1 
ATOM   7056  C  C   . VAL B 2 494 ? 114.909 119.972 64.008  1.00 231.30 ? 494 VAL B C   1 
ATOM   7057  O  O   . VAL B 2 494 ? 115.724 119.210 63.498  1.00 261.40 ? 494 VAL B O   1 
ATOM   7058  C  CB  . VAL B 2 494 ? 113.684 121.302 62.217  1.00 329.29 ? 494 VAL B CB  1 
ATOM   7059  C  CG1 . VAL B 2 494 ? 112.348 121.510 61.511  1.00 321.28 ? 494 VAL B CG1 1 
ATOM   7060  C  CG2 . VAL B 2 494 ? 114.234 122.629 62.734  1.00 366.38 ? 494 VAL B CG2 1 
ATOM   7061  N  N   . LEU B 2 495 ? 115.130 120.604 65.167  1.00 223.67 ? 495 LEU B N   1 
ATOM   7062  C  CA  . LEU B 2 495 ? 116.277 120.281 66.010  1.00 266.50 ? 495 LEU B CA  1 
ATOM   7063  C  C   . LEU B 2 495 ? 116.229 118.804 66.416  1.00 244.77 ? 495 LEU B C   1 
ATOM   7064  O  O   . LEU B 2 495 ? 117.200 118.100 66.187  1.00 219.44 ? 495 LEU B O   1 
ATOM   7065  C  CB  . LEU B 2 495 ? 116.315 121.232 67.222  1.00 318.74 ? 495 LEU B CB  1 
ATOM   7066  C  CG  . LEU B 2 495 ? 117.445 121.061 68.253  1.00 351.48 ? 495 LEU B CG  1 
ATOM   7067  C  CD1 . LEU B 2 495 ? 117.197 119.908 69.226  1.00 347.98 ? 495 LEU B CD1 1 
ATOM   7068  C  CD2 . LEU B 2 495 ? 118.810 120.889 67.587  1.00 363.32 ? 495 LEU B CD2 1 
ATOM   7069  N  N   . CYS B 2 496 ? 115.121 118.322 66.992  1.00 242.00 ? 496 CYS B N   1 
ATOM   7070  C  CA  . CYS B 2 496 ? 115.048 116.933 67.434  1.00 267.82 ? 496 CYS B CA  1 
ATOM   7071  C  C   . CYS B 2 496 ? 115.242 115.961 66.263  1.00 222.52 ? 496 CYS B C   1 
ATOM   7072  O  O   . CYS B 2 496 ? 115.976 114.970 66.406  1.00 173.07 ? 496 CYS B O   1 
ATOM   7073  C  CB  . CYS B 2 496 ? 113.740 116.669 68.177  1.00 329.85 ? 496 CYS B CB  1 
ATOM   7074  S  SG  . CYS B 2 496 ? 113.695 117.507 69.784  1.00 330.79 ? 496 CYS B SG  1 
ATOM   7075  N  N   . GLN B 2 497 ? 114.619 116.238 65.108  1.00 198.58 ? 497 GLN B N   1 
ATOM   7076  C  CA  . GLN B 2 497 ? 114.806 115.402 63.933  1.00 201.96 ? 497 GLN B CA  1 
ATOM   7077  C  C   . GLN B 2 497 ? 116.288 115.273 63.588  1.00 221.16 ? 497 GLN B C   1 
ATOM   7078  O  O   . GLN B 2 497 ? 116.711 114.157 63.318  1.00 146.75 ? 497 GLN B O   1 
ATOM   7079  C  CB  . GLN B 2 497 ? 114.036 115.956 62.739  1.00 202.00 ? 497 GLN B CB  1 
ATOM   7080  C  CG  . GLN B 2 497 ? 112.536 115.753 62.807  1.00 188.23 ? 497 GLN B CG  1 
ATOM   7081  C  CD  . GLN B 2 497 ? 111.926 116.002 61.447  1.00 298.27 ? 497 GLN B CD  1 
ATOM   7082  O  OE1 . GLN B 2 497 ? 111.320 117.041 61.190  1.00 378.52 ? 497 GLN B OE1 1 
ATOM   7083  N  NE2 . GLN B 2 497 ? 112.091 115.051 60.540  1.00 334.71 ? 497 GLN B NE2 1 
ATOM   7084  N  N   . LYS B 2 498 ? 117.036 116.401 63.585  1.00 273.53 ? 498 LYS B N   1 
ATOM   7085  C  CA  . LYS B 2 498 ? 118.472 116.489 63.305  1.00 288.13 ? 498 LYS B CA  1 
ATOM   7086  C  C   . LYS B 2 498 ? 119.268 115.703 64.348  1.00 275.27 ? 498 LYS B C   1 
ATOM   7087  O  O   . LYS B 2 498 ? 120.191 114.949 64.004  1.00 253.68 ? 498 LYS B O   1 
ATOM   7088  C  CB  . LYS B 2 498 ? 118.930 117.962 63.324  1.00 261.02 ? 498 LYS B CB  1 
ATOM   7089  C  CG  . LYS B 2 498 ? 120.210 118.305 62.578  1.00 284.70 ? 498 LYS B CG  1 
ATOM   7090  C  CD  . LYS B 2 498 ? 120.045 118.328 61.082  1.00 340.30 ? 498 LYS B CD  1 
ATOM   7091  C  CE  . LYS B 2 498 ? 119.041 119.361 60.603  1.00 376.17 ? 498 LYS B CE  1 
ATOM   7092  N  NZ  . LYS B 2 498 ? 119.432 120.748 60.962  1.00 364.07 ? 498 LYS B NZ  1 
ATOM   7093  N  N   . LEU B 2 499 ? 118.874 115.900 65.621  1.00 242.75 ? 499 LEU B N   1 
ATOM   7094  C  CA  . LEU B 2 499 ? 119.618 115.478 66.788  1.00 226.60 ? 499 LEU B CA  1 
ATOM   7095  C  C   . LEU B 2 499 ? 119.605 113.963 66.954  1.00 219.45 ? 499 LEU B C   1 
ATOM   7096  O  O   . LEU B 2 499 ? 120.594 113.449 67.489  1.00 217.93 ? 499 LEU B O   1 
ATOM   7097  C  CB  . LEU B 2 499 ? 119.013 116.196 68.000  1.00 220.09 ? 499 LEU B CB  1 
ATOM   7098  C  CG  . LEU B 2 499 ? 119.721 115.971 69.330  1.00 384.64 ? 499 LEU B CG  1 
ATOM   7099  C  CD1 . LEU B 2 499 ? 121.182 116.406 69.276  1.00 412.80 ? 499 LEU B CD1 1 
ATOM   7100  C  CD2 . LEU B 2 499 ? 118.991 116.730 70.429  1.00 458.10 ? 499 LEU B CD2 1 
ATOM   7101  N  N   . MET B 2 500 ? 118.529 113.268 66.533  1.00 226.67 ? 500 MET B N   1 
ATOM   7102  C  CA  . MET B 2 500 ? 118.524 111.797 66.594  1.00 274.93 ? 500 MET B CA  1 
ATOM   7103  C  C   . MET B 2 500 ? 118.145 111.108 65.267  1.00 241.05 ? 500 MET B C   1 
ATOM   7104  O  O   . MET B 2 500 ? 117.894 109.896 65.270  1.00 190.34 ? 500 MET B O   1 
ATOM   7105  C  CB  . MET B 2 500 ? 117.639 111.299 67.758  1.00 281.34 ? 500 MET B CB  1 
ATOM   7106  C  CG  . MET B 2 500 ? 116.130 111.634 67.671  1.00 300.33 ? 500 MET B CG  1 
ATOM   7107  S  SD  . MET B 2 500 ? 115.259 111.553 69.287  1.00 239.69 ? 500 MET B SD  1 
ATOM   7108  C  CE  . MET B 2 500 ? 115.827 113.075 70.053  1.00 236.42 ? 500 MET B CE  1 
ATOM   7109  N  N   . GLN B 2 501 ? 118.133 111.869 64.149  1.00 236.56 ? 501 GLN B N   1 
ATOM   7110  C  CA  . GLN B 2 501 ? 118.014 111.378 62.775  1.00 260.54 ? 501 GLN B CA  1 
ATOM   7111  C  C   . GLN B 2 501 ? 116.698 110.607 62.593  1.00 262.49 ? 501 GLN B C   1 
ATOM   7112  O  O   . GLN B 2 501 ? 116.699 109.401 62.351  1.00 219.34 ? 501 GLN B O   1 
ATOM   7113  C  CB  . GLN B 2 501 ? 119.283 110.589 62.417  1.00 284.16 ? 501 GLN B CB  1 
ATOM   7114  C  CG  . GLN B 2 501 ? 119.432 110.221 60.940  1.00 275.94 ? 501 GLN B CG  1 
ATOM   7115  C  CD  . GLN B 2 501 ? 120.578 109.265 60.685  1.00 298.92 ? 501 GLN B CD  1 
ATOM   7116  O  OE1 . GLN B 2 501 ? 121.532 109.169 61.459  1.00 276.54 ? 501 GLN B OE1 1 
ATOM   7117  N  NE2 . GLN B 2 501 ? 120.502 108.544 59.575  1.00 318.41 ? 501 GLN B NE2 1 
ATOM   7118  N  N   . VAL B 2 502 ? 115.567 111.325 62.715  1.00 232.53 ? 502 VAL B N   1 
ATOM   7119  C  CA  . VAL B 2 502 ? 114.236 110.733 62.623  1.00 197.64 ? 502 VAL B CA  1 
ATOM   7120  C  C   . VAL B 2 502 ? 113.325 111.524 61.688  1.00 234.28 ? 502 VAL B C   1 
ATOM   7121  O  O   . VAL B 2 502 ? 113.460 112.735 61.528  1.00 212.81 ? 502 VAL B O   1 
ATOM   7122  C  CB  . VAL B 2 502 ? 113.592 110.606 64.010  1.00 187.05 ? 502 VAL B CB  1 
ATOM   7123  C  CG1 . VAL B 2 502 ? 114.377 109.611 64.846  1.00 219.66 ? 502 VAL B CG1 1 
ATOM   7124  C  CG2 . VAL B 2 502 ? 113.467 111.945 64.729  1.00 200.17 ? 502 VAL B CG2 1 
ATOM   7125  N  N   . VAL B 2 503 ? 112.376 110.793 61.075  1.00 234.42 ? 503 VAL B N   1 
ATOM   7126  C  CA  . VAL B 2 503 ? 111.593 111.262 59.941  1.00 193.22 ? 503 VAL B CA  1 
ATOM   7127  C  C   . VAL B 2 503 ? 110.137 110.819 60.064  1.00 208.85 ? 503 VAL B C   1 
ATOM   7128  O  O   . VAL B 2 503 ? 109.855 109.819 60.728  1.00 306.60 ? 503 VAL B O   1 
ATOM   7129  C  CB  . VAL B 2 503 ? 112.181 110.698 58.645  1.00 215.63 ? 503 VAL B CB  1 
ATOM   7130  C  CG1 . VAL B 2 503 ? 113.647 111.078 58.488  1.00 296.17 ? 503 VAL B CG1 1 
ATOM   7131  C  CG2 . VAL B 2 503 ? 111.990 109.185 58.548  1.00 130.62 ? 503 VAL B CG2 1 
ATOM   7132  N  N   . PRO B 2 504 ? 109.164 111.519 59.447  1.00 165.76 ? 504 PRO B N   1 
ATOM   7133  C  CA  . PRO B 2 504 ? 107.765 111.076 59.522  1.00 181.33 ? 504 PRO B CA  1 
ATOM   7134  C  C   . PRO B 2 504 ? 107.554 109.747 58.789  1.00 232.13 ? 504 PRO B C   1 
ATOM   7135  O  O   . PRO B 2 504 ? 108.245 109.458 57.814  1.00 213.94 ? 504 PRO B O   1 
ATOM   7136  C  CB  . PRO B 2 504 ? 106.950 112.206 58.880  1.00 216.24 ? 504 PRO B CB  1 
ATOM   7137  C  CG  . PRO B 2 504 ? 107.936 113.378 58.751  1.00 256.51 ? 504 PRO B CG  1 
ATOM   7138  C  CD  . PRO B 2 504 ? 109.334 112.772 58.694  1.00 197.76 ? 504 PRO B CD  1 
ATOM   7139  N  N   . GLN B 2 505 ? 106.602 108.947 59.282  1.00 280.70 ? 505 GLN B N   1 
ATOM   7140  C  CA  . GLN B 2 505 ? 106.212 107.696 58.633  1.00 280.72 ? 505 GLN B CA  1 
ATOM   7141  C  C   . GLN B 2 505 ? 105.450 107.990 57.337  1.00 253.64 ? 505 GLN B C   1 
ATOM   7142  O  O   . GLN B 2 505 ? 104.866 109.063 57.171  1.00 232.30 ? 505 GLN B O   1 
ATOM   7143  C  CB  . GLN B 2 505 ? 105.418 106.788 59.590  1.00 312.83 ? 505 GLN B CB  1 
ATOM   7144  C  CG  . GLN B 2 505 ? 103.896 106.964 59.608  1.00 307.46 ? 505 GLN B CG  1 
ATOM   7145  C  CD  . GLN B 2 505 ? 103.414 108.360 59.938  1.00 344.42 ? 505 GLN B CD  1 
ATOM   7146  O  OE1 . GLN B 2 505 ? 104.090 109.140 60.608  1.00 346.10 ? 505 GLN B OE1 1 
ATOM   7147  N  NE2 . GLN B 2 505 ? 102.227 108.693 59.460  1.00 382.83 ? 505 GLN B NE2 1 
ATOM   7148  N  N   . GLU B 2 506 ? 105.466 107.010 56.425  1.00 287.09 ? 506 GLU B N   1 
ATOM   7149  C  CA  . GLU B 2 506 ? 104.869 107.152 55.104  1.00 373.97 ? 506 GLU B CA  1 
ATOM   7150  C  C   . GLU B 2 506 ? 103.606 106.294 55.014  1.00 450.51 ? 506 GLU B C   1 
ATOM   7151  O  O   . GLU B 2 506 ? 103.651 105.090 55.281  1.00 458.71 ? 506 GLU B O   1 
ATOM   7152  C  CB  . GLU B 2 506 ? 105.884 106.748 54.034  1.00 401.90 ? 506 GLU B CB  1 
ATOM   7153  C  CG  . GLU B 2 506 ? 107.096 107.668 53.958  1.00 379.45 ? 506 GLU B CG  1 
ATOM   7154  C  CD  . GLU B 2 506 ? 108.247 107.142 53.116  1.00 377.46 ? 506 GLU B CD  1 
ATOM   7155  O  OE1 . GLU B 2 506 ? 108.503 105.922 53.169  1.00 402.50 ? 506 GLU B OE1 1 
ATOM   7156  O  OE2 . GLU B 2 506 ? 108.892 107.957 52.422  1.00 317.72 ? 506 GLU B OE2 1 
ATOM   7157  N  N   . THR B 2 507 ? 102.470 106.908 54.625  1.00 474.40 ? 507 THR B N   1 
ATOM   7158  C  CA  . THR B 2 507 ? 101.230 106.171 54.375  1.00 471.52 ? 507 THR B CA  1 
ATOM   7159  C  C   . THR B 2 507 ? 101.405 105.273 53.138  1.00 345.95 ? 507 THR B C   1 
ATOM   7160  O  O   . THR B 2 507 ? 101.027 104.082 53.232  1.00 286.54 ? 507 THR B O   1 
ATOM   7161  C  CB  . THR B 2 507 ? 100.008 107.091 54.196  1.00 490.02 ? 507 THR B CB  1 
ATOM   7162  O  OG1 . THR B 2 507 ? 100.009 108.144 55.164  1.00 487.88 ? 507 THR B OG1 1 
ATOM   7163  C  CG2 . THR B 2 507 ? 98.697  106.341 54.317  1.00 491.50 ? 507 THR B CG2 1 
ATOM   7164  N  N   . ASP C 3 1   ? 98.258  122.989 131.878 1.00 251.84 ? 1   ASP L N   1 
ATOM   7165  C  CA  . ASP C 3 1   ? 98.264  122.685 133.335 1.00 227.50 ? 1   ASP L CA  1 
ATOM   7166  C  C   . ASP C 3 1   ? 96.875  122.936 133.920 1.00 171.01 ? 1   ASP L C   1 
ATOM   7167  O  O   . ASP C 3 1   ? 96.064  123.656 133.336 1.00 249.35 ? 1   ASP L O   1 
ATOM   7168  C  CB  . ASP C 3 1   ? 99.302  123.545 134.075 1.00 339.25 ? 1   ASP L CB  1 
ATOM   7169  C  CG  . ASP C 3 1   ? 100.711 123.559 133.494 1.00 451.67 ? 1   ASP L CG  1 
ATOM   7170  O  OD1 . ASP C 3 1   ? 100.925 122.934 132.433 1.00 530.53 ? 1   ASP L OD1 1 
ATOM   7171  O  OD2 . ASP C 3 1   ? 101.589 124.199 134.109 1.00 465.15 ? 1   ASP L OD2 1 
ATOM   7172  N  N   . ILE C 3 2   ? 96.599  122.354 135.087 1.00 124.64 ? 2   ILE L N   1 
ATOM   7173  C  CA  . ILE C 3 2   ? 95.461  122.775 135.915 1.00 132.77 ? 2   ILE L CA  1 
ATOM   7174  C  C   . ILE C 3 2   ? 95.623  124.240 136.368 1.00 132.05 ? 2   ILE L C   1 
ATOM   7175  O  O   . ILE C 3 2   ? 96.731  124.736 136.505 1.00 174.37 ? 2   ILE L O   1 
ATOM   7176  C  CB  . ILE C 3 2   ? 95.266  121.775 137.089 1.00 104.06 ? 2   ILE L CB  1 
ATOM   7177  C  CG1 . ILE C 3 2   ? 94.758  120.458 136.508 1.00 127.72 ? 2   ILE L CG1 1 
ATOM   7178  C  CG2 . ILE C 3 2   ? 94.380  122.248 138.254 1.00 71.34  ? 2   ILE L CG2 1 
ATOM   7179  C  CD1 . ILE C 3 2   ? 94.853  119.299 137.467 1.00 177.79 ? 2   ILE L CD1 1 
ATOM   7180  N  N   . VAL C 3 3   ? 94.497  124.924 136.591 1.00 126.51 ? 3   VAL L N   1 
ATOM   7181  C  CA  . VAL C 3 3   ? 94.457  126.280 137.120 1.00 145.44 ? 3   VAL L CA  1 
ATOM   7182  C  C   . VAL C 3 3   ? 93.531  126.308 138.324 1.00 125.65 ? 3   VAL L C   1 
ATOM   7183  O  O   . VAL C 3 3   ? 92.453  125.713 138.252 1.00 115.91 ? 3   VAL L O   1 
ATOM   7184  C  CB  . VAL C 3 3   ? 93.984  127.285 136.058 1.00 217.65 ? 3   VAL L CB  1 
ATOM   7185  C  CG1 . VAL C 3 3   ? 93.833  128.693 136.645 1.00 253.28 ? 3   VAL L CG1 1 
ATOM   7186  C  CG2 . VAL C 3 3   ? 94.902  127.261 134.834 1.00 254.82 ? 3   VAL L CG2 1 
ATOM   7187  N  N   . LEU C 3 4   ? 93.968  126.997 139.403 1.00 130.30 ? 4   LEU L N   1 
ATOM   7188  C  CA  . LEU C 3 4   ? 93.163  127.106 140.616 1.00 145.31 ? 4   LEU L CA  1 
ATOM   7189  C  C   . LEU C 3 4   ? 92.817  128.562 140.863 1.00 173.48 ? 4   LEU L C   1 
ATOM   7190  O  O   . LEU C 3 4   ? 93.678  129.354 141.212 1.00 223.07 ? 4   LEU L O   1 
ATOM   7191  C  CB  . LEU C 3 4   ? 93.858  126.431 141.807 1.00 126.20 ? 4   LEU L CB  1 
ATOM   7192  C  CG  . LEU C 3 4   ? 93.920  124.892 141.671 1.00 165.22 ? 4   LEU L CG  1 
ATOM   7193  C  CD1 . LEU C 3 4   ? 95.303  124.522 141.199 1.00 193.66 ? 4   LEU L CD1 1 
ATOM   7194  C  CD2 . LEU C 3 4   ? 93.534  124.077 142.938 1.00 100.87 ? 4   LEU L CD2 1 
ATOM   7195  N  N   . THR C 3 5   ? 91.535  128.899 140.654 1.00 200.63 ? 5   THR L N   1 
ATOM   7196  C  CA  . THR C 3 5   ? 90.990  130.180 141.061 1.00 200.21 ? 5   THR L CA  1 
ATOM   7197  C  C   . THR C 3 5   ? 90.806  130.128 142.568 1.00 140.62 ? 5   THR L C   1 
ATOM   7198  O  O   . THR C 3 5   ? 90.347  129.095 143.091 1.00 132.77 ? 5   THR L O   1 
ATOM   7199  C  CB  . THR C 3 5   ? 89.661  130.467 140.346 1.00 297.54 ? 5   THR L CB  1 
ATOM   7200  O  OG1 . THR C 3 5   ? 89.891  130.492 138.934 1.00 363.89 ? 5   THR L OG1 1 
ATOM   7201  C  CG2 . THR C 3 5   ? 89.018  131.775 140.764 1.00 322.90 ? 5   THR L CG2 1 
ATOM   7202  N  N   . GLN C 3 6   ? 91.141  131.237 143.244 1.00 116.41 ? 6   GLN L N   1 
ATOM   7203  C  CA  . GLN C 3 6   ? 90.844  131.325 144.666 1.00 151.14 ? 6   GLN L CA  1 
ATOM   7204  C  C   . GLN C 3 6   ? 90.122  132.625 145.013 1.00 216.43 ? 6   GLN L C   1 
ATOM   7205  O  O   . GLN C 3 6   ? 90.423  133.662 144.419 1.00 302.23 ? 6   GLN L O   1 
ATOM   7206  C  CB  . GLN C 3 6   ? 92.170  131.198 145.395 1.00 165.87 ? 6   GLN L CB  1 
ATOM   7207  C  CG  . GLN C 3 6   ? 92.001  130.765 146.840 1.00 160.73 ? 6   GLN L CG  1 
ATOM   7208  C  CD  . GLN C 3 6   ? 93.326  130.679 147.562 1.00 153.88 ? 6   GLN L CD  1 
ATOM   7209  O  OE1 . GLN C 3 6   ? 94.348  130.207 147.046 1.00 86.17  ? 6   GLN L OE1 1 
ATOM   7210  N  NE2 . GLN C 3 6   ? 93.324  131.152 148.797 1.00 192.96 ? 6   GLN L NE2 1 
ATOM   7211  N  N   . SER C 3 7   ? 89.177  132.559 145.975 1.00 201.97 ? 7   SER L N   1 
ATOM   7212  C  CA  . SER C 3 7   ? 88.412  133.734 146.379 1.00 199.26 ? 7   SER L CA  1 
ATOM   7213  C  C   . SER C 3 7   ? 87.874  133.605 147.811 1.00 185.69 ? 7   SER L C   1 
ATOM   7214  O  O   . SER C 3 7   ? 87.724  132.506 148.335 1.00 189.93 ? 7   SER L O   1 
ATOM   7215  C  CB  . SER C 3 7   ? 87.299  134.011 145.386 1.00 220.73 ? 7   SER L CB  1 
ATOM   7216  O  OG  . SER C 3 7   ? 86.227  133.088 145.528 1.00 276.03 ? 7   SER L OG  1 
ATOM   7217  N  N   . PRO C 3 8   ? 87.552  134.713 148.514 1.00 209.76 ? 8   PRO L N   1 
ATOM   7218  C  CA  . PRO C 3 8   ? 87.853  136.078 148.063 1.00 227.19 ? 8   PRO L CA  1 
ATOM   7219  C  C   . PRO C 3 8   ? 89.347  136.345 148.207 1.00 225.88 ? 8   PRO L C   1 
ATOM   7220  O  O   . PRO C 3 8   ? 90.032  135.626 148.950 1.00 316.50 ? 8   PRO L O   1 
ATOM   7221  C  CB  . PRO C 3 8   ? 87.010  136.941 149.006 1.00 266.49 ? 8   PRO L CB  1 
ATOM   7222  C  CG  . PRO C 3 8   ? 86.972  136.132 150.289 1.00 252.56 ? 8   PRO L CG  1 
ATOM   7223  C  CD  . PRO C 3 8   ? 86.874  134.693 149.821 1.00 228.51 ? 8   PRO L CD  1 
ATOM   7224  N  N   . SER C 3 9   ? 89.844  137.372 147.498 1.00 173.64 ? 9   SER L N   1 
ATOM   7225  C  CA  . SER C 3 9   ? 91.262  137.717 147.563 1.00 201.13 ? 9   SER L CA  1 
ATOM   7226  C  C   . SER C 3 9   ? 91.622  138.313 148.931 1.00 197.70 ? 9   SER L C   1 
ATOM   7227  O  O   . SER C 3 9   ? 92.775  138.201 149.365 1.00 250.98 ? 9   SER L O   1 
ATOM   7228  C  CB  . SER C 3 9   ? 91.647  138.638 146.447 1.00 210.97 ? 9   SER L CB  1 
ATOM   7229  O  OG  . SER C 3 9   ? 90.925  139.855 146.544 1.00 282.04 ? 9   SER L OG  1 
ATOM   7230  N  N   . SER C 3 10  ? 90.633  138.943 149.590 1.00 161.51 ? 10  SER L N   1 
ATOM   7231  C  CA  . SER C 3 10  ? 90.758  139.471 150.938 1.00 181.88 ? 10  SER L CA  1 
ATOM   7232  C  C   . SER C 3 10  ? 89.611  138.948 151.783 1.00 152.30 ? 10  SER L C   1 
ATOM   7233  O  O   . SER C 3 10  ? 88.495  138.864 151.303 1.00 178.13 ? 10  SER L O   1 
ATOM   7234  C  CB  . SER C 3 10  ? 90.773  140.996 150.923 1.00 233.72 ? 10  SER L CB  1 
ATOM   7235  O  OG  . SER C 3 10  ? 90.579  141.571 152.221 1.00 182.48 ? 10  SER L OG  1 
ATOM   7236  N  N   . LEU C 3 11  ? 89.878  138.641 153.047 1.00 160.77 ? 11  LEU L N   1 
ATOM   7237  C  CA  . LEU C 3 11  ? 88.818  138.216 153.941 1.00 174.50 ? 11  LEU L CA  1 
ATOM   7238  C  C   . LEU C 3 11  ? 89.017  138.830 155.319 1.00 188.15 ? 11  LEU L C   1 
ATOM   7239  O  O   . LEU C 3 11  ? 89.531  138.184 156.223 1.00 244.26 ? 11  LEU L O   1 
ATOM   7240  C  CB  . LEU C 3 11  ? 88.867  136.693 153.955 1.00 204.04 ? 11  LEU L CB  1 
ATOM   7241  C  CG  . LEU C 3 11  ? 87.936  135.951 154.911 1.00 251.26 ? 11  LEU L CG  1 
ATOM   7242  C  CD1 . LEU C 3 11  ? 86.475  136.321 154.700 1.00 330.14 ? 11  LEU L CD1 1 
ATOM   7243  C  CD2 . LEU C 3 11  ? 88.150  134.472 154.701 1.00 283.22 ? 11  LEU L CD2 1 
ATOM   7244  N  N   . ALA C 3 12  ? 88.593  140.090 155.477 1.00 208.12 ? 12  ALA L N   1 
ATOM   7245  C  CA  . ALA C 3 12  ? 88.739  140.772 156.758 1.00 243.87 ? 12  ALA L CA  1 
ATOM   7246  C  C   . ALA C 3 12  ? 87.689  140.218 157.728 1.00 188.79 ? 12  ALA L C   1 
ATOM   7247  O  O   . ALA C 3 12  ? 86.505  140.282 157.396 1.00 218.47 ? 12  ALA L O   1 
ATOM   7248  C  CB  . ALA C 3 12  ? 88.619  142.266 156.566 1.00 279.98 ? 12  ALA L CB  1 
ATOM   7249  N  N   . MET C 3 13  ? 88.109  139.670 158.895 1.00 183.84 ? 13  MET L N   1 
ATOM   7250  C  CA  . MET C 3 13  ? 87.168  139.148 159.890 1.00 218.08 ? 13  MET L CA  1 
ATOM   7251  C  C   . MET C 3 13  ? 87.667  139.350 161.322 1.00 204.32 ? 13  MET L C   1 
ATOM   7252  O  O   . MET C 3 13  ? 88.848  139.528 161.559 1.00 216.55 ? 13  MET L O   1 
ATOM   7253  C  CB  . MET C 3 13  ? 86.834  137.668 159.647 1.00 219.32 ? 13  MET L CB  1 
ATOM   7254  C  CG  . MET C 3 13  ? 85.654  137.485 158.654 1.00 321.55 ? 13  MET L CG  1 
ATOM   7255  S  SD  . MET C 3 13  ? 84.008  138.190 159.078 1.00 414.29 ? 13  MET L SD  1 
ATOM   7256  C  CE  . MET C 3 13  ? 83.502  137.244 160.512 1.00 376.76 ? 13  MET L CE  1 
ATOM   7257  N  N   . SER C 3 14  ? 86.713  139.333 162.277 1.00 252.08 ? 14  SER L N   1 
ATOM   7258  C  CA  . SER C 3 14  ? 86.925  139.711 163.674 1.00 245.63 ? 14  SER L CA  1 
ATOM   7259  C  C   . SER C 3 14  ? 87.347  138.511 164.521 1.00 215.40 ? 14  SER L C   1 
ATOM   7260  O  O   . SER C 3 14  ? 86.997  137.370 164.207 1.00 195.50 ? 14  SER L O   1 
ATOM   7261  C  CB  . SER C 3 14  ? 85.684  140.314 164.267 1.00 254.04 ? 14  SER L CB  1 
ATOM   7262  O  OG  . SER C 3 14  ? 85.207  141.384 163.483 1.00 230.56 ? 14  SER L OG  1 
ATOM   7263  N  N   . VAL C 3 15  ? 88.085  138.785 165.615 1.00 166.22 ? 15  VAL L N   1 
ATOM   7264  C  CA  . VAL C 3 15  ? 88.662  137.716 166.430 1.00 196.16 ? 15  VAL L CA  1 
ATOM   7265  C  C   . VAL C 3 15  ? 87.543  136.890 167.069 1.00 185.71 ? 15  VAL L C   1 
ATOM   7266  O  O   . VAL C 3 15  ? 86.548  137.451 167.524 1.00 228.69 ? 15  VAL L O   1 
ATOM   7267  C  CB  . VAL C 3 15  ? 89.638  138.274 167.484 1.00 254.62 ? 15  VAL L CB  1 
ATOM   7268  C  CG1 . VAL C 3 15  ? 90.089  137.214 168.508 1.00 252.59 ? 15  VAL L CG1 1 
ATOM   7269  C  CG2 . VAL C 3 15  ? 90.830  138.949 166.803 1.00 241.20 ? 15  VAL L CG2 1 
ATOM   7270  N  N   . GLY C 3 16  ? 87.714  135.558 167.082 1.00 173.76 ? 16  GLY L N   1 
ATOM   7271  C  CA  . GLY C 3 16  ? 86.708  134.625 167.572 1.00 215.95 ? 16  GLY L CA  1 
ATOM   7272  C  C   . GLY C 3 16  ? 85.742  134.083 166.503 1.00 254.86 ? 16  GLY L C   1 
ATOM   7273  O  O   . GLY C 3 16  ? 85.129  133.038 166.734 1.00 245.38 ? 16  GLY L O   1 
ATOM   7274  N  N   . GLN C 3 17  ? 85.590  134.756 165.341 1.00 236.20 ? 17  GLN L N   1 
ATOM   7275  C  CA  . GLN C 3 17  ? 84.601  134.371 164.334 1.00 219.43 ? 17  GLN L CA  1 
ATOM   7276  C  C   . GLN C 3 17  ? 85.097  133.245 163.416 1.00 215.87 ? 17  GLN L C   1 
ATOM   7277  O  O   . GLN C 3 17  ? 86.289  133.011 163.290 1.00 212.00 ? 17  GLN L O   1 
ATOM   7278  C  CB  . GLN C 3 17  ? 84.209  135.593 163.497 1.00 213.16 ? 17  GLN L CB  1 
ATOM   7279  C  CG  . GLN C 3 17  ? 83.590  136.731 164.303 1.00 277.53 ? 17  GLN L CG  1 
ATOM   7280  C  CD  . GLN C 3 17  ? 82.309  136.382 165.029 1.00 358.23 ? 17  GLN L CD  1 
ATOM   7281  O  OE1 . GLN C 3 17  ? 81.603  135.435 164.684 1.00 371.25 ? 17  GLN L OE1 1 
ATOM   7282  N  NE2 . GLN C 3 17  ? 81.989  137.161 166.053 1.00 402.39 ? 17  GLN L NE2 1 
ATOM   7283  N  N   . LYS C 3 18  ? 84.144  132.553 162.768 1.00 216.24 ? 18  LYS L N   1 
ATOM   7284  C  CA  . LYS C 3 18  ? 84.399  131.529 161.759 1.00 198.17 ? 18  LYS L CA  1 
ATOM   7285  C  C   . LYS C 3 18  ? 84.620  132.158 160.383 1.00 222.15 ? 18  LYS L C   1 
ATOM   7286  O  O   . LYS C 3 18  ? 83.917  133.114 160.048 1.00 189.59 ? 18  LYS L O   1 
ATOM   7287  C  CB  . LYS C 3 18  ? 83.200  130.580 161.672 1.00 234.81 ? 18  LYS L CB  1 
ATOM   7288  C  CG  . LYS C 3 18  ? 83.281  129.467 160.638 1.00 238.74 ? 18  LYS L CG  1 
ATOM   7289  C  CD  . LYS C 3 18  ? 82.078  128.555 160.721 1.00 238.81 ? 18  LYS L CD  1 
ATOM   7290  C  CE  . LYS C 3 18  ? 82.162  127.357 159.803 1.00 289.42 ? 18  LYS L CE  1 
ATOM   7291  N  NZ  . LYS C 3 18  ? 81.254  126.265 160.232 1.00 319.21 ? 18  LYS L NZ  1 
ATOM   7292  N  N   . VAL C 3 19  ? 85.582  131.612 159.593 1.00 235.88 ? 19  VAL L N   1 
ATOM   7293  C  CA  . VAL C 3 19  ? 85.944  132.132 158.266 1.00 237.32 ? 19  VAL L CA  1 
ATOM   7294  C  C   . VAL C 3 19  ? 86.181  130.998 157.268 1.00 181.19 ? 19  VAL L C   1 
ATOM   7295  O  O   . VAL C 3 19  ? 86.526  129.882 157.656 1.00 111.52 ? 19  VAL L O   1 
ATOM   7296  C  CB  . VAL C 3 19  ? 87.184  133.046 158.287 1.00 208.41 ? 19  VAL L CB  1 
ATOM   7297  C  CG1 . VAL C 3 19  ? 87.058  134.135 159.324 1.00 275.32 ? 19  VAL L CG1 1 
ATOM   7298  C  CG2 . VAL C 3 19  ? 88.470  132.289 158.507 1.00 194.85 ? 19  VAL L CG2 1 
ATOM   7299  N  N   . THR C 3 20  ? 85.994  131.331 155.977 1.00 165.99 ? 20  THR L N   1 
ATOM   7300  C  CA  . THR C 3 20  ? 85.968  130.374 154.883 1.00 191.38 ? 20  THR L CA  1 
ATOM   7301  C  C   . THR C 3 20  ? 86.740  130.932 153.682 1.00 218.21 ? 20  THR L C   1 
ATOM   7302  O  O   . THR C 3 20  ? 86.460  132.049 153.233 1.00 181.39 ? 20  THR L O   1 
ATOM   7303  C  CB  . THR C 3 20  ? 84.522  130.030 154.490 1.00 233.52 ? 20  THR L CB  1 
ATOM   7304  O  OG1 . THR C 3 20  ? 83.856  129.410 155.592 1.00 199.43 ? 20  THR L OG1 1 
ATOM   7305  C  CG2 . THR C 3 20  ? 84.420  129.087 153.310 1.00 272.45 ? 20  THR L CG2 1 
ATOM   7306  N  N   . MET C 3 21  ? 87.681  130.111 153.176 1.00 196.12 ? 21  MET L N   1 
ATOM   7307  C  CA  . MET C 3 21  ? 88.378  130.307 151.912 1.00 146.86 ? 21  MET L CA  1 
ATOM   7308  C  C   . MET C 3 21  ? 87.711  129.382 150.881 1.00 136.63 ? 21  MET L C   1 
ATOM   7309  O  O   . MET C 3 21  ? 87.388  128.239 151.219 1.00 90.35  ? 21  MET L O   1 
ATOM   7310  C  CB  . MET C 3 21  ? 89.853  129.904 152.037 1.00 160.10 ? 21  MET L CB  1 
ATOM   7311  C  CG  . MET C 3 21  ? 90.526  130.142 153.392 1.00 146.86 ? 21  MET L CG  1 
ATOM   7312  S  SD  . MET C 3 21  ? 90.829  131.847 153.725 1.00 196.31 ? 21  MET L SD  1 
ATOM   7313  C  CE  . MET C 3 21  ? 91.723  131.797 155.282 1.00 124.95 ? 21  MET L CE  1 
ATOM   7314  N  N   . ASN C 3 22  ? 87.518  129.844 149.637 1.00 130.74 ? 22  ASN L N   1 
ATOM   7315  C  CA  . ASN C 3 22  ? 87.099  128.975 148.541 1.00 155.60 ? 22  ASN L CA  1 
ATOM   7316  C  C   . ASN C 3 22  ? 88.224  128.805 147.518 1.00 168.34 ? 22  ASN L C   1 
ATOM   7317  O  O   . ASN C 3 22  ? 88.919  129.768 147.147 1.00 201.22 ? 22  ASN L O   1 
ATOM   7318  C  CB  . ASN C 3 22  ? 85.861  129.511 147.833 1.00 223.79 ? 22  ASN L CB  1 
ATOM   7319  C  CG  . ASN C 3 22  ? 84.627  129.413 148.696 1.00 280.83 ? 22  ASN L CG  1 
ATOM   7320  O  OD1 . ASN C 3 22  ? 84.012  128.350 148.761 1.00 227.51 ? 22  ASN L OD1 1 
ATOM   7321  N  ND2 . ASN C 3 22  ? 84.270  130.511 149.351 1.00 346.02 ? 22  ASN L ND2 1 
ATOM   7322  N  N   . CYS C 3 23  ? 88.385  127.556 147.064 1.00 145.28 ? 23  CYS L N   1 
ATOM   7323  C  CA  . CYS C 3 23  ? 89.339  127.201 146.029 1.00 163.86 ? 23  CYS L CA  1 
ATOM   7324  C  C   . CYS C 3 23  ? 88.588  126.421 144.959 1.00 150.56 ? 23  CYS L C   1 
ATOM   7325  O  O   . CYS C 3 23  ? 87.764  125.570 145.319 1.00 178.42 ? 23  CYS L O   1 
ATOM   7326  C  CB  . CYS C 3 23  ? 90.498  126.393 146.610 1.00 160.56 ? 23  CYS L CB  1 
ATOM   7327  S  SG  . CYS C 3 23  ? 91.725  125.873 145.367 1.00 207.12 ? 23  CYS L SG  1 
ATOM   7328  N  N   . LYS C 3 24  ? 88.887  126.719 143.682 1.00 120.61 ? 24  LYS L N   1 
ATOM   7329  C  CA  . LYS C 3 24  ? 88.083  126.251 142.574 1.00 139.74 ? 24  LYS L CA  1 
ATOM   7330  C  C   . LYS C 3 24  ? 88.989  125.821 141.424 1.00 140.98 ? 24  LYS L C   1 
ATOM   7331  O  O   . LYS C 3 24  ? 89.626  126.683 140.810 1.00 130.99 ? 24  LYS L O   1 
ATOM   7332  C  CB  . LYS C 3 24  ? 87.131  127.384 142.179 1.00 227.35 ? 24  LYS L CB  1 
ATOM   7333  C  CG  . LYS C 3 24  ? 86.162  127.095 141.034 1.00 269.68 ? 24  LYS L CG  1 
ATOM   7334  C  CD  . LYS C 3 24  ? 85.238  125.929 141.301 1.00 301.66 ? 24  LYS L CD  1 
ATOM   7335  C  CE  . LYS C 3 24  ? 84.149  125.794 140.260 1.00 340.54 ? 24  LYS L CE  1 
ATOM   7336  N  NZ  . LYS C 3 24  ? 83.251  124.657 140.566 1.00 392.47 ? 24  LYS L NZ  1 
ATOM   7337  N  N   . SER C 3 25  ? 89.010  124.501 141.133 1.00 148.00 ? 25  SER L N   1 
ATOM   7338  C  CA  . SER C 3 25  ? 89.977  123.889 140.221 1.00 146.66 ? 25  SER L CA  1 
ATOM   7339  C  C   . SER C 3 25  ? 89.430  123.653 138.810 1.00 118.61 ? 25  SER L C   1 
ATOM   7340  O  O   . SER C 3 25  ? 88.318  123.159 138.645 1.00 114.42 ? 25  SER L O   1 
ATOM   7341  C  CB  . SER C 3 25  ? 90.464  122.600 140.789 1.00 148.35 ? 25  SER L CB  1 
ATOM   7342  O  OG  . SER C 3 25  ? 89.368  121.755 141.014 1.00 151.54 ? 25  SER L OG  1 
ATOM   7343  N  N   . SER C 3 26  ? 90.247  123.973 137.785 1.00 118.10 ? 26  SER L N   1 
ATOM   7344  C  CA  . SER C 3 26  ? 89.880  123.775 136.384 1.00 165.44 ? 26  SER L CA  1 
ATOM   7345  C  C   . SER C 3 26  ? 89.808  122.302 135.923 1.00 149.47 ? 26  SER L C   1 
ATOM   7346  O  O   . SER C 3 26  ? 89.540  122.043 134.749 1.00 190.43 ? 26  SER L O   1 
ATOM   7347  C  CB  . SER C 3 26  ? 90.813  124.567 135.485 1.00 203.61 ? 26  SER L CB  1 
ATOM   7348  O  OG  . SER C 3 26  ? 92.058  123.917 135.303 1.00 184.12 ? 26  SER L OG  1 
ATOM   7349  N  N   . GLN C 3 27  ? 90.058  121.336 136.811 1.00 157.46 ? 27  GLN L N   1 
ATOM   7350  C  CA  . GLN C 3 27  ? 89.693  119.942 136.614 1.00 152.83 ? 27  GLN L CA  1 
ATOM   7351  C  C   . GLN C 3 27  ? 89.331  119.333 137.948 1.00 134.24 ? 27  GLN L C   1 
ATOM   7352  O  O   . GLN C 3 27  ? 89.576  119.920 138.987 1.00 125.70 ? 27  GLN L O   1 
ATOM   7353  C  CB  . GLN C 3 27  ? 90.850  119.083 136.110 1.00 164.66 ? 27  GLN L CB  1 
ATOM   7354  C  CG  . GLN C 3 27  ? 91.286  119.378 134.689 1.00 244.03 ? 27  GLN L CG  1 
ATOM   7355  C  CD  . GLN C 3 27  ? 92.352  118.386 134.264 1.00 291.14 ? 27  GLN L CD  1 
ATOM   7356  O  OE1 . GLN C 3 27  ? 93.255  118.710 133.487 1.00 365.82 ? 27  GLN L OE1 1 
ATOM   7357  N  NE2 . GLN C 3 27  ? 92.256  117.159 134.776 1.00 203.89 ? 27  GLN L NE2 1 
ATOM   7358  N  N   . SER C 3 28  ? 88.741  118.150 137.899 1.00 141.24 ? 28  SER L N   1 
ATOM   7359  C  CA  . SER C 3 28  ? 88.474  117.396 139.110 1.00 157.15 ? 28  SER L CA  1 
ATOM   7360  C  C   . SER C 3 28  ? 89.795  116.898 139.691 1.00 122.83 ? 28  SER L C   1 
ATOM   7361  O  O   . SER C 3 28  ? 90.703  116.497 138.982 1.00 96.56  ? 28  SER L O   1 
ATOM   7362  C  CB  . SER C 3 28  ? 87.546  116.254 138.820 1.00 218.20 ? 28  SER L CB  1 
ATOM   7363  O  OG  . SER C 3 28  ? 87.298  115.487 139.971 1.00 181.20 ? 28  SER L OG  1 
ATOM   7364  N  N   . LEU C 3 29  ? 89.883  116.915 141.015 1.00 118.46 ? 29  LEU L N   1 
ATOM   7365  C  CA  . LEU C 3 29  ? 91.013  116.380 141.757 1.00 92.63  ? 29  LEU L CA  1 
ATOM   7366  C  C   . LEU C 3 29  ? 90.503  115.269 142.670 1.00 119.31 ? 29  LEU L C   1 
ATOM   7367  O  O   . LEU C 3 29  ? 91.118  115.055 143.692 1.00 88.94  ? 29  LEU L O   1 
ATOM   7368  C  CB  . LEU C 3 29  ? 91.646  117.459 142.642 1.00 78.13  ? 29  LEU L CB  1 
ATOM   7369  C  CG  . LEU C 3 29  ? 91.773  118.850 142.028 1.00 86.57  ? 29  LEU L CG  1 
ATOM   7370  C  CD1 . LEU C 3 29  ? 92.203  119.876 143.134 1.00 85.37  ? 29  LEU L CD1 1 
ATOM   7371  C  CD2 . LEU C 3 29  ? 92.713  118.869 140.812 1.00 83.34  ? 29  LEU L CD2 1 
ATOM   7372  N  N   . LEU C 3 30  ? 89.416  114.571 142.298 1.00 131.39 ? 30  LEU L N   1 
ATOM   7373  C  CA  . LEU C 3 30  ? 89.081  113.278 142.874 1.00 148.78 ? 30  LEU L CA  1 
ATOM   7374  C  C   . LEU C 3 30  ? 89.769  112.187 142.046 1.00 176.63 ? 30  LEU L C   1 
ATOM   7375  O  O   . LEU C 3 30  ? 89.594  112.097 140.815 1.00 126.56 ? 30  LEU L O   1 
ATOM   7376  C  CB  . LEU C 3 30  ? 87.562  113.108 142.847 1.00 198.55 ? 30  LEU L CB  1 
ATOM   7377  C  CG  . LEU C 3 30  ? 87.030  111.743 143.289 1.00 233.90 ? 30  LEU L CG  1 
ATOM   7378  C  CD1 . LEU C 3 30  ? 87.497  111.411 144.696 1.00 154.37 ? 30  LEU L CD1 1 
ATOM   7379  C  CD2 . LEU C 3 30  ? 85.509  111.698 143.195 1.00 304.06 ? 30  LEU L CD2 1 
ATOM   7380  N  N   . ASN C 3 31  ? 90.555  111.338 142.730 1.00 168.13 ? 31  ASN L N   1 
ATOM   7381  C  CA  . ASN C 3 31  ? 91.156  110.162 142.117 1.00 143.44 ? 31  ASN L CA  1 
ATOM   7382  C  C   . ASN C 3 31  ? 90.162  109.007 142.273 1.00 182.56 ? 31  ASN L C   1 
ATOM   7383  O  O   . ASN C 3 31  ? 90.029  108.418 143.348 1.00 121.32 ? 31  ASN L O   1 
ATOM   7384  C  CB  . ASN C 3 31  ? 92.531  109.897 142.740 1.00 170.18 ? 31  ASN L CB  1 
ATOM   7385  C  CG  . ASN C 3 31  ? 93.201  108.623 142.290 1.00 167.57 ? 31  ASN L CG  1 
ATOM   7386  O  OD1 . ASN C 3 31  ? 92.862  108.042 141.255 1.00 247.17 ? 31  ASN L OD1 1 
ATOM   7387  N  ND2 . ASN C 3 31  ? 94.144  108.160 143.092 1.00 149.23 ? 31  ASN L ND2 1 
ATOM   7388  N  N   . ASN C 3 32  ? 89.484  108.657 141.166 1.00 226.98 ? 32  ASN L N   1 
ATOM   7389  C  CA  . ASN C 3 32  ? 88.429  107.636 141.106 1.00 195.36 ? 32  ASN L CA  1 
ATOM   7390  C  C   . ASN C 3 32  ? 88.859  106.303 141.728 1.00 167.75 ? 32  ASN L C   1 
ATOM   7391  O  O   . ASN C 3 32  ? 88.096  105.670 142.440 1.00 129.10 ? 32  ASN L O   1 
ATOM   7392  C  CB  . ASN C 3 32  ? 88.008  107.366 139.655 1.00 193.35 ? 32  ASN L CB  1 
ATOM   7393  C  CG  . ASN C 3 32  ? 87.531  108.604 138.922 1.00 268.59 ? 32  ASN L CG  1 
ATOM   7394  O  OD1 . ASN C 3 32  ? 86.713  109.370 139.438 1.00 274.22 ? 32  ASN L OD1 1 
ATOM   7395  N  ND2 . ASN C 3 32  ? 88.045  108.810 137.719 1.00 319.64 ? 32  ASN L ND2 1 
ATOM   7396  N  N   . ASN C 3 33  ? 90.107  105.898 141.451 1.00 234.06 ? 33  ASN L N   1 
ATOM   7397  C  CA  . ASN C 3 33  ? 90.667  104.617 141.860 1.00 186.47 ? 33  ASN L CA  1 
ATOM   7398  C  C   . ASN C 3 33  ? 90.791  104.497 143.377 1.00 160.88 ? 33  ASN L C   1 
ATOM   7399  O  O   . ASN C 3 33  ? 90.948  103.380 143.861 1.00 188.53 ? 33  ASN L O   1 
ATOM   7400  C  CB  . ASN C 3 33  ? 92.062  104.388 141.255 1.00 193.20 ? 33  ASN L CB  1 
ATOM   7401  C  CG  . ASN C 3 33  ? 92.118  104.654 139.759 1.00 268.81 ? 33  ASN L CG  1 
ATOM   7402  O  OD1 . ASN C 3 33  ? 91.537  103.920 138.956 1.00 233.19 ? 33  ASN L OD1 1 
ATOM   7403  N  ND2 . ASN C 3 33  ? 92.810  105.717 139.379 1.00 332.69 ? 33  ASN L ND2 1 
ATOM   7404  N  N   . ASN C 3 34  ? 90.745  105.628 144.112 1.00 162.89 ? 34  ASN L N   1 
ATOM   7405  C  CA  . ASN C 3 34  ? 91.149  105.651 145.513 1.00 171.99 ? 34  ASN L CA  1 
ATOM   7406  C  C   . ASN C 3 34  ? 90.226  106.464 146.419 1.00 191.77 ? 34  ASN L C   1 
ATOM   7407  O  O   . ASN C 3 34  ? 90.395  106.355 147.635 1.00 208.93 ? 34  ASN L O   1 
ATOM   7408  C  CB  . ASN C 3 34  ? 92.597  106.131 145.621 1.00 166.38 ? 34  ASN L CB  1 
ATOM   7409  C  CG  . ASN C 3 34  ? 93.250  105.746 146.922 1.00 220.01 ? 34  ASN L CG  1 
ATOM   7410  O  OD1 . ASN C 3 34  ? 93.755  106.608 147.625 1.00 270.73 ? 34  ASN L OD1 1 
ATOM   7411  N  ND2 . ASN C 3 34  ? 93.246  104.462 147.257 1.00 257.36 ? 34  ASN L ND2 1 
ATOM   7412  N  N   . GLN C 3 35  ? 89.277  107.249 145.867 1.00 202.20 ? 35  GLN L N   1 
ATOM   7413  C  CA  . GLN C 3 35  ? 88.226  107.907 146.631 1.00 219.78 ? 35  GLN L CA  1 
ATOM   7414  C  C   . GLN C 3 35  ? 88.832  108.855 147.673 1.00 211.50 ? 35  GLN L C   1 
ATOM   7415  O  O   . GLN C 3 35  ? 88.415  108.861 148.844 1.00 234.52 ? 35  GLN L O   1 
ATOM   7416  C  CB  . GLN C 3 35  ? 87.265  106.873 147.239 1.00 244.33 ? 35  GLN L CB  1 
ATOM   7417  C  CG  . GLN C 3 35  ? 86.552  106.007 146.207 1.00 258.36 ? 35  GLN L CG  1 
ATOM   7418  C  CD  . GLN C 3 35  ? 85.660  106.804 145.278 1.00 329.53 ? 35  GLN L CD  1 
ATOM   7419  O  OE1 . GLN C 3 35  ? 84.878  107.642 145.722 1.00 360.45 ? 35  GLN L OE1 1 
ATOM   7420  N  NE2 . GLN C 3 35  ? 85.759  106.560 143.974 1.00 356.18 ? 35  GLN L NE2 1 
ATOM   7421  N  N   . LYS C 3 36  ? 89.815  109.667 147.228 1.00 196.12 ? 36  LYS L N   1 
ATOM   7422  C  CA  . LYS C 3 36  ? 90.221  110.859 147.957 1.00 186.41 ? 36  LYS L CA  1 
ATOM   7423  C  C   . LYS C 3 36  ? 90.650  111.948 146.981 1.00 160.23 ? 36  LYS L C   1 
ATOM   7424  O  O   . LYS C 3 36  ? 90.930  111.699 145.797 1.00 105.45 ? 36  LYS L O   1 
ATOM   7425  C  CB  . LYS C 3 36  ? 91.295  110.558 149.001 1.00 177.83 ? 36  LYS L CB  1 
ATOM   7426  C  CG  . LYS C 3 36  ? 92.649  110.158 148.477 1.00 159.78 ? 36  LYS L CG  1 
ATOM   7427  C  CD  . LYS C 3 36  ? 93.424  109.381 149.527 1.00 184.73 ? 36  LYS L CD  1 
ATOM   7428  C  CE  . LYS C 3 36  ? 94.843  109.094 149.096 1.00 285.89 ? 36  LYS L CE  1 
ATOM   7429  N  NZ  . LYS C 3 36  ? 95.381  107.906 149.803 1.00 345.45 ? 36  LYS L NZ  1 
ATOM   7430  N  N   . ASN C 3 37  ? 90.653  113.170 147.539 1.00 151.83 ? 37  ASN L N   1 
ATOM   7431  C  CA  . ASN C 3 37  ? 90.714  114.394 146.771 1.00 129.18 ? 37  ASN L CA  1 
ATOM   7432  C  C   . ASN C 3 37  ? 92.059  115.034 147.054 1.00 130.97 ? 37  ASN L C   1 
ATOM   7433  O  O   . ASN C 3 37  ? 92.440  115.265 148.197 1.00 128.60 ? 37  ASN L O   1 
ATOM   7434  C  CB  . ASN C 3 37  ? 89.590  115.337 147.143 1.00 127.59 ? 37  ASN L CB  1 
ATOM   7435  C  CG  . ASN C 3 37  ? 88.222  114.883 146.713 1.00 209.00 ? 37  ASN L CG  1 
ATOM   7436  O  OD1 . ASN C 3 37  ? 87.799  115.252 145.624 1.00 131.16 ? 37  ASN L OD1 1 
ATOM   7437  N  ND2 . ASN C 3 37  ? 87.525  114.133 147.561 1.00 255.16 ? 37  ASN L ND2 1 
ATOM   7438  N  N   . TYR C 3 38  ? 92.791  115.331 145.991 1.00 113.33 ? 38  TYR L N   1 
ATOM   7439  C  CA  . TYR C 3 38  ? 94.143  115.845 146.131 1.00 106.42 ? 38  TYR L CA  1 
ATOM   7440  C  C   . TYR C 3 38  ? 94.138  117.355 146.184 1.00 89.42  ? 38  TYR L C   1 
ATOM   7441  O  O   . TYR C 3 38  ? 94.039  117.977 145.166 1.00 88.98  ? 38  TYR L O   1 
ATOM   7442  C  CB  . TYR C 3 38  ? 94.914  115.260 144.954 1.00 105.02 ? 38  TYR L CB  1 
ATOM   7443  C  CG  . TYR C 3 38  ? 95.186  113.760 144.984 1.00 103.86 ? 38  TYR L CG  1 
ATOM   7444  C  CD1 . TYR C 3 38  ? 95.003  112.977 146.115 1.00 157.62 ? 38  TYR L CD1 1 
ATOM   7445  C  CD2 . TYR C 3 38  ? 95.628  113.099 143.896 1.00 80.16  ? 38  TYR L CD2 1 
ATOM   7446  C  CE1 . TYR C 3 38  ? 95.259  111.615 146.148 1.00 141.84 ? 38  TYR L CE1 1 
ATOM   7447  C  CE2 . TYR C 3 38  ? 95.891  111.749 143.908 1.00 106.13 ? 38  TYR L CE2 1 
ATOM   7448  C  CZ  . TYR C 3 38  ? 95.704  110.983 145.025 1.00 101.36 ? 38  TYR L CZ  1 
ATOM   7449  O  OH  . TYR C 3 38  ? 95.947  109.641 144.990 1.00 165.10 ? 38  TYR L OH  1 
ATOM   7450  N  N   . LEU C 3 39  ? 94.226  117.926 147.382 1.00 103.53 ? 39  LEU L N   1 
ATOM   7451  C  CA  . LEU C 3 39  ? 94.432  119.359 147.583 1.00 101.70 ? 39  LEU L CA  1 
ATOM   7452  C  C   . LEU C 3 39  ? 95.092  119.648 148.918 1.00 95.63  ? 39  LEU L C   1 
ATOM   7453  O  O   . LEU C 3 39  ? 94.956  118.856 149.846 1.00 78.69  ? 39  LEU L O   1 
ATOM   7454  C  CB  . LEU C 3 39  ? 93.115  120.075 147.652 1.00 92.63  ? 39  LEU L CB  1 
ATOM   7455  C  CG  . LEU C 3 39  ? 93.218  121.544 147.409 1.00 100.59 ? 39  LEU L CG  1 
ATOM   7456  C  CD1 . LEU C 3 39  ? 93.289  121.769 145.861 1.00 118.05 ? 39  LEU L CD1 1 
ATOM   7457  C  CD2 . LEU C 3 39  ? 92.031  122.178 148.141 1.00 147.84 ? 39  LEU L CD2 1 
ATOM   7458  N  N   . ALA C 3 40  ? 95.815  120.771 148.981 1.00 80.61  ? 40  ALA L N   1 
ATOM   7459  C  CA  . ALA C 3 40  ? 96.461  121.188 150.194 1.00 85.74  ? 40  ALA L CA  1 
ATOM   7460  C  C   . ALA C 3 40  ? 96.366  122.684 150.337 1.00 107.06 ? 40  ALA L C   1 
ATOM   7461  O  O   . ALA C 3 40  ? 96.282  123.376 149.342 1.00 86.02  ? 40  ALA L O   1 
ATOM   7462  C  CB  . ALA C 3 40  ? 97.923  120.808 150.157 1.00 97.69  ? 40  ALA L CB  1 
ATOM   7463  N  N   . TRP C 3 41  ? 96.432  123.116 151.613 1.00 124.47 ? 41  TRP L N   1 
ATOM   7464  C  CA  . TRP C 3 41  ? 96.375  124.497 152.051 1.00 92.48  ? 41  TRP L CA  1 
ATOM   7465  C  C   . TRP C 3 41  ? 97.667  124.894 152.758 1.00 92.42  ? 41  TRP L C   1 
ATOM   7466  O  O   . TRP C 3 41  ? 98.095  124.202 153.670 1.00 82.39  ? 41  TRP L O   1 
ATOM   7467  C  CB  . TRP C 3 41  ? 95.170  124.628 152.992 1.00 84.87  ? 41  TRP L CB  1 
ATOM   7468  C  CG  . TRP C 3 41  ? 93.897  124.683 152.209 1.00 95.56  ? 41  TRP L CG  1 
ATOM   7469  C  CD1 . TRP C 3 41  ? 93.103  123.618 151.990 1.00 126.43 ? 41  TRP L CD1 1 
ATOM   7470  C  CD2 . TRP C 3 41  ? 93.294  125.786 151.497 1.00 103.74 ? 41  TRP L CD2 1 
ATOM   7471  N  NE1 . TRP C 3 41  ? 92.047  123.968 151.209 1.00 117.24 ? 41  TRP L NE1 1 
ATOM   7472  C  CE2 . TRP C 3 41  ? 92.140  125.289 150.891 1.00 95.15  ? 41  TRP L CE2 1 
ATOM   7473  C  CE3 . TRP C 3 41  ? 93.610  127.130 151.311 1.00 133.42 ? 41  TRP L CE3 1 
ATOM   7474  C  CZ2 . TRP C 3 41  ? 91.304  126.077 150.116 1.00 98.09  ? 41  TRP L CZ2 1 
ATOM   7475  C  CZ3 . TRP C 3 41  ? 92.782  127.918 150.548 1.00 149.69 ? 41  TRP L CZ3 1 
ATOM   7476  C  CH2 . TRP C 3 41  ? 91.649  127.394 149.942 1.00 121.99 ? 41  TRP L CH2 1 
ATOM   7477  N  N   . TYR C 3 42  ? 98.279  126.006 152.358 1.00 70.27  ? 42  TYR L N   1 
ATOM   7478  C  CA  . TYR C 3 42  ? 99.447  126.488 153.065 1.00 75.02  ? 42  TYR L CA  1 
ATOM   7479  C  C   . TYR C 3 42  ? 99.163  127.890 153.561 1.00 94.83  ? 42  TYR L C   1 
ATOM   7480  O  O   . TYR C 3 42  ? 98.581  128.681 152.843 1.00 99.70  ? 42  TYR L O   1 
ATOM   7481  C  CB  . TYR C 3 42  ? 100.691 126.647 152.204 1.00 92.17  ? 42  TYR L CB  1 
ATOM   7482  C  CG  . TYR C 3 42  ? 101.098 125.374 151.479 1.00 102.20 ? 42  TYR L CG  1 
ATOM   7483  C  CD1 . TYR C 3 42  ? 100.565 124.991 150.249 1.00 83.95  ? 42  TYR L CD1 1 
ATOM   7484  C  CD2 . TYR C 3 42  ? 102.039 124.554 152.044 1.00 89.28  ? 42  TYR L CD2 1 
ATOM   7485  C  CE1 . TYR C 3 42  ? 100.971 123.830 149.612 1.00 76.58  ? 42  TYR L CE1 1 
ATOM   7486  C  CE2 . TYR C 3 42  ? 102.455 123.393 151.418 1.00 74.65  ? 42  TYR L CE2 1 
ATOM   7487  C  CZ  . TYR C 3 42  ? 101.925 123.016 150.199 1.00 88.98  ? 42  TYR L CZ  1 
ATOM   7488  O  OH  . TYR C 3 42  ? 102.391 121.857 149.621 1.00 96.46  ? 42  TYR L OH  1 
ATOM   7489  N  N   . GLN C 3 43  ? 99.589  128.167 154.790 1.00 123.73 ? 43  GLN L N   1 
ATOM   7490  C  CA  . GLN C 3 43  ? 99.533  129.469 155.433 1.00 119.25 ? 43  GLN L CA  1 
ATOM   7491  C  C   . GLN C 3 43  ? 100.901 130.117 155.254 1.00 107.76 ? 43  GLN L C   1 
ATOM   7492  O  O   . GLN C 3 43  ? 101.925 129.480 155.498 1.00 126.03 ? 43  GLN L O   1 
ATOM   7493  C  CB  . GLN C 3 43  ? 99.252  129.243 156.919 1.00 135.21 ? 43  GLN L CB  1 
ATOM   7494  C  CG  . GLN C 3 43  ? 99.355  130.484 157.785 1.00 148.38 ? 43  GLN L CG  1 
ATOM   7495  C  CD  . GLN C 3 43  ? 99.326  130.310 159.287 1.00 164.78 ? 43  GLN L CD  1 
ATOM   7496  O  OE1 . GLN C 3 43  ? 99.364  131.284 160.021 1.00 266.13 ? 43  GLN L OE1 1 
ATOM   7497  N  NE2 . GLN C 3 43  ? 99.240  129.102 159.798 1.00 155.15 ? 43  GLN L NE2 1 
ATOM   7498  N  N   . GLN C 3 44  ? 100.951 131.372 154.846 1.00 101.90 ? 44  GLN L N   1 
ATOM   7499  C  CA  . GLN C 3 44  ? 102.230 132.075 154.796 1.00 137.45 ? 44  GLN L CA  1 
ATOM   7500  C  C   . GLN C 3 44  ? 102.078 133.396 155.548 1.00 113.15 ? 44  GLN L C   1 
ATOM   7501  O  O   . GLN C 3 44  ? 101.421 134.357 155.063 1.00 87.94  ? 44  GLN L O   1 
ATOM   7502  C  CB  . GLN C 3 44  ? 102.717 132.279 153.361 1.00 142.82 ? 44  GLN L CB  1 
ATOM   7503  C  CG  . GLN C 3 44  ? 103.989 133.065 153.302 1.00 116.31 ? 44  GLN L CG  1 
ATOM   7504  C  CD  . GLN C 3 44  ? 104.556 133.050 151.925 1.00 145.69 ? 44  GLN L CD  1 
ATOM   7505  O  OE1 . GLN C 3 44  ? 103.841 133.041 150.930 1.00 145.52 ? 44  GLN L OE1 1 
ATOM   7506  N  NE2 . GLN C 3 44  ? 105.874 133.083 151.864 1.00 253.57 ? 44  GLN L NE2 1 
ATOM   7507  N  N   . LYS C 3 45  ? 102.687 133.390 156.748 1.00 97.93  ? 45  LYS L N   1 
ATOM   7508  C  CA  . LYS C 3 45  ? 102.641 134.562 157.586 1.00 141.23 ? 45  LYS L CA  1 
ATOM   7509  C  C   . LYS C 3 45  ? 103.566 135.594 156.945 1.00 168.48 ? 45  LYS L C   1 
ATOM   7510  O  O   . LYS C 3 45  ? 104.501 135.231 156.217 1.00 171.28 ? 45  LYS L O   1 
ATOM   7511  C  CB  . LYS C 3 45  ? 103.016 134.202 159.025 1.00 155.97 ? 45  LYS L CB  1 
ATOM   7512  C  CG  . LYS C 3 45  ? 101.950 133.496 159.857 1.00 162.72 ? 45  LYS L CG  1 
ATOM   7513  C  CD  . LYS C 3 45  ? 102.379 133.436 161.324 1.00 235.29 ? 45  LYS L CD  1 
ATOM   7514  C  CE  . LYS C 3 45  ? 101.973 132.175 162.071 1.00 264.27 ? 45  LYS L CE  1 
ATOM   7515  N  NZ  . LYS C 3 45  ? 100.521 132.103 162.357 1.00 237.98 ? 45  LYS L NZ  1 
ATOM   7516  N  N   . PRO C 3 46  ? 103.361 136.904 157.217 1.00 187.82 ? 46  PRO L N   1 
ATOM   7517  C  CA  . PRO C 3 46  ? 104.208 137.928 156.623 1.00 195.58 ? 46  PRO L CA  1 
ATOM   7518  C  C   . PRO C 3 46  ? 105.633 137.732 157.168 1.00 239.98 ? 46  PRO L C   1 
ATOM   7519  O  O   . PRO C 3 46  ? 105.847 137.600 158.388 1.00 182.81 ? 46  PRO L O   1 
ATOM   7520  C  CB  . PRO C 3 46  ? 103.520 139.231 157.054 1.00 231.00 ? 46  PRO L CB  1 
ATOM   7521  C  CG  . PRO C 3 46  ? 102.866 138.856 158.367 1.00 251.08 ? 46  PRO L CG  1 
ATOM   7522  C  CD  . PRO C 3 46  ? 102.341 137.458 158.122 1.00 217.41 ? 46  PRO L CD  1 
ATOM   7523  N  N   . GLY C 3 47  ? 106.596 137.690 156.226 1.00 247.77 ? 47  GLY L N   1 
ATOM   7524  C  CA  . GLY C 3 47  ? 108.018 137.573 156.514 1.00 233.01 ? 47  GLY L CA  1 
ATOM   7525  C  C   . GLY C 3 47  ? 108.524 136.149 156.778 1.00 231.00 ? 47  GLY L C   1 
ATOM   7526  O  O   . GLY C 3 47  ? 109.638 136.020 157.290 1.00 244.59 ? 47  GLY L O   1 
ATOM   7527  N  N   . GLN C 3 48  ? 107.744 135.097 156.433 1.00 207.73 ? 48  GLN L N   1 
ATOM   7528  C  CA  . GLN C 3 48  ? 108.120 133.698 156.674 1.00 167.96 ? 48  GLN L CA  1 
ATOM   7529  C  C   . GLN C 3 48  ? 107.836 132.805 155.453 1.00 158.42 ? 48  GLN L C   1 
ATOM   7530  O  O   . GLN C 3 48  ? 107.262 133.217 154.448 1.00 199.31 ? 48  GLN L O   1 
ATOM   7531  C  CB  . GLN C 3 48  ? 107.400 133.151 157.915 1.00 159.00 ? 48  GLN L CB  1 
ATOM   7532  C  CG  . GLN C 3 48  ? 107.638 133.951 159.191 1.00 190.63 ? 48  GLN L CG  1 
ATOM   7533  C  CD  . GLN C 3 48  ? 106.872 133.444 160.392 1.00 211.60 ? 48  GLN L CD  1 
ATOM   7534  O  OE1 . GLN C 3 48  ? 106.323 132.344 160.413 1.00 206.05 ? 48  GLN L OE1 1 
ATOM   7535  N  NE2 . GLN C 3 48  ? 106.822 134.268 161.427 1.00 248.00 ? 48  GLN L NE2 1 
ATOM   7536  N  N   . SER C 3 49  ? 108.256 131.536 155.554 1.00 157.40 ? 49  SER L N   1 
ATOM   7537  C  CA  . SER C 3 49  ? 108.065 130.501 154.544 1.00 134.64 ? 49  SER L CA  1 
ATOM   7538  C  C   . SER C 3 49  ? 106.645 129.987 154.550 1.00 101.84 ? 49  SER L C   1 
ATOM   7539  O  O   . SER C 3 49  ? 105.971 130.144 155.549 1.00 160.70 ? 49  SER L O   1 
ATOM   7540  C  CB  . SER C 3 49  ? 109.014 129.333 154.832 1.00 182.56 ? 49  SER L CB  1 
ATOM   7541  O  OG  . SER C 3 49  ? 108.911 128.838 156.177 1.00 149.13 ? 49  SER L OG  1 
ATOM   7542  N  N   . PRO C 3 50  ? 106.133 129.299 153.510 1.00 108.33 ? 50  PRO L N   1 
ATOM   7543  C  CA  . PRO C 3 50  ? 104.851 128.579 153.632 1.00 126.49 ? 50  PRO L CA  1 
ATOM   7544  C  C   . PRO C 3 50  ? 104.877 127.449 154.676 1.00 126.94 ? 50  PRO L C   1 
ATOM   7545  O  O   . PRO C 3 50  ? 105.860 126.707 154.752 1.00 110.11 ? 50  PRO L O   1 
ATOM   7546  C  CB  . PRO C 3 50  ? 104.624 127.946 152.245 1.00 97.32  ? 50  PRO L CB  1 
ATOM   7547  C  CG  . PRO C 3 50  ? 105.575 128.709 151.344 1.00 87.48  ? 50  PRO L CG  1 
ATOM   7548  C  CD  . PRO C 3 50  ? 106.748 129.136 152.195 1.00 89.90  ? 50  PRO L CD  1 
ATOM   7549  N  N   . LYS C 3 51  ? 103.797 127.312 155.476 1.00 104.05 ? 51  LYS L N   1 
ATOM   7550  C  CA  . LYS C 3 51  ? 103.582 126.180 156.380 1.00 115.56 ? 51  LYS L CA  1 
ATOM   7551  C  C   . LYS C 3 51  ? 102.429 125.358 155.810 1.00 108.17 ? 51  LYS L C   1 
ATOM   7552  O  O   . LYS C 3 51  ? 101.410 125.912 155.453 1.00 87.13  ? 51  LYS L O   1 
ATOM   7553  C  CB  . LYS C 3 51  ? 103.268 126.635 157.812 1.00 148.30 ? 51  LYS L CB  1 
ATOM   7554  C  CG  . LYS C 3 51  ? 102.815 125.538 158.775 1.00 157.01 ? 51  LYS L CG  1 
ATOM   7555  C  CD  . LYS C 3 51  ? 102.434 126.050 160.157 1.00 208.00 ? 51  LYS L CD  1 
ATOM   7556  C  CE  . LYS C 3 51  ? 102.184 124.895 161.111 1.00 306.31 ? 51  LYS L CE  1 
ATOM   7557  N  NZ  . LYS C 3 51  ? 101.789 125.288 162.490 1.00 324.25 ? 51  LYS L NZ  1 
ATOM   7558  N  N   . LEU C 3 52  ? 102.585 124.035 155.738 1.00 117.83 ? 52  LEU L N   1 
ATOM   7559  C  CA  . LEU C 3 52  ? 101.555 123.152 155.218 1.00 93.88  ? 52  LEU L CA  1 
ATOM   7560  C  C   . LEU C 3 52  ? 100.529 122.949 156.314 1.00 108.49 ? 52  LEU L C   1 
ATOM   7561  O  O   . LEU C 3 52  ? 100.922 122.632 157.452 1.00 114.76 ? 52  LEU L O   1 
ATOM   7562  C  CB  . LEU C 3 52  ? 102.282 121.855 154.878 1.00 116.59 ? 52  LEU L CB  1 
ATOM   7563  C  CG  . LEU C 3 52  ? 101.463 120.672 154.381 1.00 135.45 ? 52  LEU L CG  1 
ATOM   7564  C  CD1 . LEU C 3 52  ? 100.584 120.974 153.178 1.00 103.60 ? 52  LEU L CD1 1 
ATOM   7565  C  CD2 . LEU C 3 52  ? 102.431 119.533 154.013 1.00 109.82 ? 52  LEU L CD2 1 
ATOM   7566  N  N   . LEU C 3 53  ? 99.228  123.114 155.983 1.00 110.66 ? 53  LEU L N   1 
ATOM   7567  C  CA  . LEU C 3 53  ? 98.146  122.961 156.974 1.00 126.91 ? 53  LEU L CA  1 
ATOM   7568  C  C   . LEU C 3 53  ? 97.487  121.612 156.813 1.00 102.77 ? 53  LEU L C   1 
ATOM   7569  O  O   . LEU C 3 53  ? 97.509  120.787 157.725 1.00 113.01 ? 53  LEU L O   1 
ATOM   7570  C  CB  . LEU C 3 53  ? 97.053  124.031 156.849 1.00 99.29  ? 53  LEU L CB  1 
ATOM   7571  C  CG  . LEU C 3 53  ? 97.550  125.459 157.058 1.00 89.18  ? 53  LEU L CG  1 
ATOM   7572  C  CD1 . LEU C 3 53  ? 96.434  126.426 156.869 1.00 110.44 ? 53  LEU L CD1 1 
ATOM   7573  C  CD2 . LEU C 3 53  ? 98.100  125.599 158.444 1.00 104.79 ? 53  LEU L CD2 1 
ATOM   7574  N  N   . VAL C 3 54  ? 96.888  121.441 155.646 1.00 109.33 ? 54  VAL L N   1 
ATOM   7575  C  CA  . VAL C 3 54  ? 96.194  120.205 155.365 1.00 134.54 ? 54  VAL L CA  1 
ATOM   7576  C  C   . VAL C 3 54  ? 96.560  119.728 153.971 1.00 113.27 ? 54  VAL L C   1 
ATOM   7577  O  O   . VAL C 3 54  ? 96.858  120.532 153.109 1.00 124.14 ? 54  VAL L O   1 
ATOM   7578  C  CB  . VAL C 3 54  ? 94.675  120.358 155.521 1.00 115.50 ? 54  VAL L CB  1 
ATOM   7579  C  CG1 . VAL C 3 54  ? 94.306  121.050 156.822 1.00 156.07 ? 54  VAL L CG1 1 
ATOM   7580  C  CG2 . VAL C 3 54  ? 94.093  121.104 154.383 1.00 88.86  ? 54  VAL L CG2 1 
ATOM   7581  N  N   . TYR C 3 55  ? 96.544  118.416 153.798 1.00 96.71  ? 55  TYR L N   1 
ATOM   7582  C  CA  . TYR C 3 55  ? 96.670  117.819 152.504 1.00 78.06  ? 55  TYR L CA  1 
ATOM   7583  C  C   . TYR C 3 55  ? 95.671  116.709 152.298 1.00 72.88  ? 55  TYR L C   1 
ATOM   7584  O  O   . TYR C 3 55  ? 94.962  116.349 153.209 1.00 123.88 ? 55  TYR L O   1 
ATOM   7585  C  CB  . TYR C 3 55  ? 98.107  117.361 152.499 1.00 102.31 ? 55  TYR L CB  1 
ATOM   7586  C  CG  . TYR C 3 55  ? 98.624  116.343 153.471 1.00 87.77  ? 55  TYR L CG  1 
ATOM   7587  C  CD1 . TYR C 3 55  ? 98.434  115.008 153.264 1.00 95.33  ? 55  TYR L CD1 1 
ATOM   7588  C  CD2 . TYR C 3 55  ? 99.366  116.758 154.548 1.00 126.03 ? 55  TYR L CD2 1 
ATOM   7589  C  CE1 . TYR C 3 55  ? 98.968  114.085 154.153 1.00 158.74 ? 55  TYR L CE1 1 
ATOM   7590  C  CE2 . TYR C 3 55  ? 99.903  115.842 155.444 1.00 211.46 ? 55  TYR L CE2 1 
ATOM   7591  C  CZ  . TYR C 3 55  ? 99.707  114.491 155.252 1.00 167.49 ? 55  TYR L CZ  1 
ATOM   7592  O  OH  . TYR C 3 55  ? 100.248 113.633 156.169 1.00 161.05 ? 55  TYR L OH  1 
ATOM   7593  N  N   . PHE C 3 56  ? 95.599  116.171 151.095 1.00 97.13  ? 56  PHE L N   1 
ATOM   7594  C  CA  . PHE C 3 56  ? 94.484  115.351 150.655 1.00 123.10 ? 56  PHE L CA  1 
ATOM   7595  C  C   . PHE C 3 56  ? 93.123  115.886 151.135 1.00 138.78 ? 56  PHE L C   1 
ATOM   7596  O  O   . PHE C 3 56  ? 92.287  115.160 151.688 1.00 156.82 ? 56  PHE L O   1 
ATOM   7597  C  CB  . PHE C 3 56  ? 94.789  113.941 151.140 1.00 135.15 ? 56  PHE L CB  1 
ATOM   7598  C  CG  . PHE C 3 56  ? 95.988  113.222 150.576 1.00 92.90  ? 56  PHE L CG  1 
ATOM   7599  C  CD1 . PHE C 3 56  ? 96.301  113.286 149.263 1.00 106.50 ? 56  PHE L CD1 1 
ATOM   7600  C  CD2 . PHE C 3 56  ? 96.757  112.409 151.364 1.00 135.39 ? 56  PHE L CD2 1 
ATOM   7601  C  CE1 . PHE C 3 56  ? 97.366  112.590 148.725 1.00 174.01 ? 56  PHE L CE1 1 
ATOM   7602  C  CE2 . PHE C 3 56  ? 97.830  111.705 150.847 1.00 220.30 ? 56  PHE L CE2 1 
ATOM   7603  C  CZ  . PHE C 3 56  ? 98.136  111.800 149.519 1.00 219.56 ? 56  PHE L CZ  1 
ATOM   7604  N  N   . THR C 3 57  ? 92.929  117.195 150.934 1.00 120.05 ? 57  THR L N   1 
ATOM   7605  C  CA  . THR C 3 57  ? 91.754  117.990 151.288 1.00 117.31 ? 57  THR L CA  1 
ATOM   7606  C  C   . THR C 3 57  ? 91.471  118.123 152.788 1.00 119.56 ? 57  THR L C   1 
ATOM   7607  O  O   . THR C 3 57  ? 90.935  119.172 153.144 1.00 123.07 ? 57  THR L O   1 
ATOM   7608  C  CB  . THR C 3 57  ? 90.499  117.487 150.621 1.00 123.30 ? 57  THR L CB  1 
ATOM   7609  O  OG1 . THR C 3 57  ? 90.846  117.439 149.250 1.00 157.77 ? 57  THR L OG1 1 
ATOM   7610  C  CG2 . THR C 3 57  ? 89.327  118.418 150.797 1.00 183.58 ? 57  THR L CG2 1 
ATOM   7611  N  N   . SER C 3 58  ? 91.812  117.158 153.648 1.00 96.35  ? 58  SER L N   1 
ATOM   7612  C  CA  . SER C 3 58  ? 91.332  117.245 155.003 1.00 146.82 ? 58  SER L CA  1 
ATOM   7613  C  C   . SER C 3 58  ? 92.353  116.892 156.072 1.00 130.60 ? 58  SER L C   1 
ATOM   7614  O  O   . SER C 3 58  ? 92.125  117.337 157.195 1.00 178.67 ? 58  SER L O   1 
ATOM   7615  C  CB  . SER C 3 58  ? 90.105  116.386 155.096 1.00 231.65 ? 58  SER L CB  1 
ATOM   7616  O  OG  . SER C 3 58  ? 90.448  115.020 154.892 1.00 197.97 ? 58  SER L OG  1 
ATOM   7617  N  N   . THR C 3 59  ? 93.386  116.124 155.712 1.00 119.92 ? 59  THR L N   1 
ATOM   7618  C  CA  . THR C 3 59  ? 94.319  115.534 156.645 1.00 163.36 ? 59  THR L CA  1 
ATOM   7619  C  C   . THR C 3 59  ? 95.184  116.663 157.173 1.00 145.42 ? 59  THR L C   1 
ATOM   7620  O  O   . THR C 3 59  ? 95.955  117.235 156.396 1.00 207.07 ? 59  THR L O   1 
ATOM   7621  C  CB  . THR C 3 59  ? 95.162  114.438 155.970 1.00 197.01 ? 59  THR L CB  1 
ATOM   7622  O  OG1 . THR C 3 59  ? 94.230  113.380 155.687 1.00 192.53 ? 59  THR L OG1 1 
ATOM   7623  C  CG2 . THR C 3 59  ? 96.382  113.995 156.777 1.00 168.26 ? 59  THR L CG2 1 
ATOM   7624  N  N   . ARG C 3 60  ? 95.013  116.958 158.463 1.00 121.04 ? 60  ARG L N   1 
ATOM   7625  C  CA  . ARG C 3 60  ? 95.824  117.943 159.140 1.00 155.48 ? 60  ARG L CA  1 
ATOM   7626  C  C   . ARG C 3 60  ? 97.247  117.413 159.246 1.00 155.85 ? 60  ARG L C   1 
ATOM   7627  O  O   . ARG C 3 60  ? 97.449  116.232 159.561 1.00 179.56 ? 60  ARG L O   1 
ATOM   7628  C  CB  . ARG C 3 60  ? 95.239  118.277 160.525 1.00 197.40 ? 60  ARG L CB  1 
ATOM   7629  C  CG  . ARG C 3 60  ? 94.336  119.498 160.498 1.00 218.35 ? 60  ARG L CG  1 
ATOM   7630  C  CD  . ARG C 3 60  ? 94.057  120.072 161.882 1.00 188.51 ? 60  ARG L CD  1 
ATOM   7631  N  NE  . ARG C 3 60  ? 93.269  119.191 162.709 1.00 202.00 ? 60  ARG L NE  1 
ATOM   7632  C  CZ  . ARG C 3 60  ? 91.983  118.903 162.520 1.00 259.34 ? 60  ARG L CZ  1 
ATOM   7633  N  NH1 . ARG C 3 60  ? 91.384  118.060 163.346 1.00 331.10 ? 60  ARG L NH1 1 
ATOM   7634  N  NH2 . ARG C 3 60  ? 91.278  119.441 161.534 1.00 227.29 ? 60  ARG L NH2 1 
ATOM   7635  N  N   . GLU C 3 61  ? 98.218  118.305 158.994 1.00 120.67 ? 61  GLU L N   1 
ATOM   7636  C  CA  . GLU C 3 61  ? 99.612  118.006 159.288 1.00 147.57 ? 61  GLU L CA  1 
ATOM   7637  C  C   . GLU C 3 61  ? 99.823  117.996 160.806 1.00 171.32 ? 61  GLU L C   1 
ATOM   7638  O  O   . GLU C 3 61  ? 99.089  118.647 161.528 1.00 177.99 ? 61  GLU L O   1 
ATOM   7639  C  CB  . GLU C 3 61  ? 100.464 119.013 158.513 1.00 142.79 ? 61  GLU L CB  1 
ATOM   7640  C  CG  . GLU C 3 61  ? 101.961 118.983 158.755 1.00 226.10 ? 61  GLU L CG  1 
ATOM   7641  C  CD  . GLU C 3 61  ? 102.710 117.670 158.547 1.00 293.86 ? 61  GLU L CD  1 
ATOM   7642  O  OE1 . GLU C 3 61  ? 102.110 116.583 158.696 1.00 314.69 ? 61  GLU L OE1 1 
ATOM   7643  O  OE2 . GLU C 3 61  ? 103.920 117.736 158.225 1.00 308.19 ? 61  GLU L OE2 1 
ATOM   7644  N  N   . SER C 3 62  ? 100.825 117.263 161.308 1.00 202.92 ? 62  SER L N   1 
ATOM   7645  C  CA  . SER C 3 62  ? 101.175 117.341 162.722 1.00 219.24 ? 62  SER L CA  1 
ATOM   7646  C  C   . SER C 3 62  ? 101.679 118.750 163.100 1.00 227.73 ? 62  SER L C   1 
ATOM   7647  O  O   . SER C 3 62  ? 102.387 119.412 162.342 1.00 198.97 ? 62  SER L O   1 
ATOM   7648  C  CB  . SER C 3 62  ? 102.173 116.246 163.088 1.00 276.39 ? 62  SER L CB  1 
ATOM   7649  O  OG  . SER C 3 62  ? 103.461 116.431 162.496 1.00 229.78 ? 62  SER L OG  1 
ATOM   7650  N  N   . GLY C 3 63  ? 101.307 119.220 164.298 1.00 241.43 ? 63  GLY L N   1 
ATOM   7651  C  CA  . GLY C 3 63  ? 101.653 120.561 164.758 1.00 242.82 ? 63  GLY L CA  1 
ATOM   7652  C  C   . GLY C 3 63  ? 100.750 121.667 164.204 1.00 176.91 ? 63  GLY L C   1 
ATOM   7653  O  O   . GLY C 3 63  ? 101.142 122.841 164.193 1.00 210.10 ? 63  GLY L O   1 
ATOM   7654  N  N   . VAL C 3 64  ? 99.551  121.275 163.753 1.00 160.92 ? 64  VAL L N   1 
ATOM   7655  C  CA  . VAL C 3 64  ? 98.568  122.200 163.216 1.00 190.05 ? 64  VAL L CA  1 
ATOM   7656  C  C   . VAL C 3 64  ? 97.409  122.252 164.204 1.00 205.87 ? 64  VAL L C   1 
ATOM   7657  O  O   . VAL C 3 64  ? 96.844  121.209 164.533 1.00 200.13 ? 64  VAL L O   1 
ATOM   7658  C  CB  . VAL C 3 64  ? 98.110  121.820 161.788 1.00 164.33 ? 64  VAL L CB  1 
ATOM   7659  C  CG1 . VAL C 3 64  ? 96.946  122.667 161.293 1.00 179.60 ? 64  VAL L CG1 1 
ATOM   7660  C  CG2 . VAL C 3 64  ? 99.247  121.953 160.783 1.00 167.38 ? 64  VAL L CG2 1 
ATOM   7661  N  N   . PRO C 3 65  ? 97.024  123.457 164.692 1.00 222.71 ? 65  PRO L N   1 
ATOM   7662  C  CA  . PRO C 3 65  ? 95.842  123.599 165.544 1.00 234.84 ? 65  PRO L CA  1 
ATOM   7663  C  C   . PRO C 3 65  ? 94.553  123.100 164.901 1.00 181.41 ? 65  PRO L C   1 
ATOM   7664  O  O   . PRO C 3 65  ? 94.355  123.278 163.710 1.00 135.97 ? 65  PRO L O   1 
ATOM   7665  C  CB  . PRO C 3 65  ? 95.725  125.112 165.752 1.00 266.87 ? 65  PRO L CB  1 
ATOM   7666  C  CG  . PRO C 3 65  ? 97.108  125.666 165.489 1.00 276.88 ? 65  PRO L CG  1 
ATOM   7667  C  CD  . PRO C 3 65  ? 97.709  124.741 164.464 1.00 217.45 ? 65  PRO L CD  1 
ATOM   7668  N  N   . ASP C 3 66  ? 93.668  122.490 165.696 1.00 199.65 ? 66  ASP L N   1 
ATOM   7669  C  CA  . ASP C 3 66  ? 92.522  121.778 165.142 1.00 256.64 ? 66  ASP L CA  1 
ATOM   7670  C  C   . ASP C 3 66  ? 91.380  122.722 164.741 1.00 215.10 ? 66  ASP L C   1 
ATOM   7671  O  O   . ASP C 3 66  ? 90.317  122.232 164.343 1.00 199.11 ? 66  ASP L O   1 
ATOM   7672  C  CB  . ASP C 3 66  ? 92.056  120.708 166.131 1.00 314.11 ? 66  ASP L CB  1 
ATOM   7673  C  CG  . ASP C 3 66  ? 93.117  119.651 166.366 1.00 358.44 ? 66  ASP L CG  1 
ATOM   7674  O  OD1 . ASP C 3 66  ? 93.227  118.726 165.526 1.00 439.63 ? 66  ASP L OD1 1 
ATOM   7675  O  OD2 . ASP C 3 66  ? 93.826  119.774 167.382 1.00 291.87 ? 66  ASP L OD2 1 
ATOM   7676  N  N   . ARG C 3 67  ? 91.586  124.051 164.831 1.00 196.27 ? 67  ARG L N   1 
ATOM   7677  C  CA  . ARG C 3 67  ? 90.654  125.020 164.264 1.00 202.52 ? 67  ARG L CA  1 
ATOM   7678  C  C   . ARG C 3 67  ? 90.695  125.074 162.733 1.00 186.32 ? 67  ARG L C   1 
ATOM   7679  O  O   . ARG C 3 67  ? 89.776  125.633 162.172 1.00 165.49 ? 67  ARG L O   1 
ATOM   7680  C  CB  . ARG C 3 67  ? 90.876  126.435 164.813 1.00 215.86 ? 67  ARG L CB  1 
ATOM   7681  C  CG  . ARG C 3 67  ? 92.235  127.069 164.543 1.00 206.71 ? 67  ARG L CG  1 
ATOM   7682  C  CD  . ARG C 3 67  ? 92.270  128.432 165.201 1.00 206.93 ? 67  ARG L CD  1 
ATOM   7683  N  NE  . ARG C 3 67  ? 93.528  129.138 165.016 1.00 179.67 ? 67  ARG L NE  1 
ATOM   7684  C  CZ  . ARG C 3 67  ? 94.622  129.032 165.782 1.00 207.95 ? 67  ARG L CZ  1 
ATOM   7685  N  NH1 . ARG C 3 67  ? 95.714  129.695 165.450 1.00 214.78 ? 67  ARG L NH1 1 
ATOM   7686  N  NH2 . ARG C 3 67  ? 94.656  128.274 166.869 1.00 199.62 ? 67  ARG L NH2 1 
ATOM   7687  N  N   . PHE C 3 68  ? 91.707  124.517 162.049 1.00 171.18 ? 68  PHE L N   1 
ATOM   7688  C  CA  . PHE C 3 68  ? 91.713  124.430 160.592 1.00 157.58 ? 68  PHE L CA  1 
ATOM   7689  C  C   . PHE C 3 68  ? 91.017  123.139 160.143 1.00 153.22 ? 68  PHE L C   1 
ATOM   7690  O  O   . PHE C 3 68  ? 91.527  122.026 160.339 1.00 160.30 ? 68  PHE L O   1 
ATOM   7691  C  CB  . PHE C 3 68  ? 93.142  124.490 160.041 1.00 168.93 ? 68  PHE L CB  1 
ATOM   7692  C  CG  . PHE C 3 68  ? 93.894  125.745 160.379 1.00 143.86 ? 68  PHE L CG  1 
ATOM   7693  C  CD1 . PHE C 3 68  ? 93.622  126.904 159.664 1.00 105.37 ? 68  PHE L CD1 1 
ATOM   7694  C  CD2 . PHE C 3 68  ? 94.858  125.766 161.404 1.00 139.53 ? 68  PHE L CD2 1 
ATOM   7695  C  CE1 . PHE C 3 68  ? 94.315  128.073 159.972 1.00 151.90 ? 68  PHE L CE1 1 
ATOM   7696  C  CE2 . PHE C 3 68  ? 95.544  126.935 161.711 1.00 132.69 ? 68  PHE L CE2 1 
ATOM   7697  C  CZ  . PHE C 3 68  ? 95.275  128.089 160.988 1.00 156.79 ? 68  PHE L CZ  1 
ATOM   7698  N  N   . ILE C 3 69  ? 89.844  123.297 159.523 1.00 146.10 ? 69  ILE L N   1 
ATOM   7699  C  CA  . ILE C 3 69  ? 89.106  122.181 158.965 1.00 169.45 ? 69  ILE L CA  1 
ATOM   7700  C  C   . ILE C 3 69  ? 89.002  122.412 157.463 1.00 148.11 ? 69  ILE L C   1 
ATOM   7701  O  O   . ILE C 3 69  ? 88.472  123.456 157.019 1.00 154.64 ? 69  ILE L O   1 
ATOM   7702  C  CB  . ILE C 3 69  ? 87.725  122.053 159.640 1.00 274.09 ? 69  ILE L CB  1 
ATOM   7703  C  CG1 . ILE C 3 69  ? 87.869  121.738 161.138 1.00 325.93 ? 69  ILE L CG1 1 
ATOM   7704  C  CG2 . ILE C 3 69  ? 86.859  121.024 158.914 1.00 322.36 ? 69  ILE L CG2 1 
ATOM   7705  C  CD1 . ILE C 3 69  ? 86.610  121.897 161.960 1.00 392.69 ? 69  ILE L CD1 1 
ATOM   7706  N  N   . GLY C 3 70  ? 89.502  121.417 156.710 1.00 119.83 ? 70  GLY L N   1 
ATOM   7707  C  CA  . GLY C 3 70  ? 89.365  121.426 155.252 1.00 163.50 ? 70  GLY L CA  1 
ATOM   7708  C  C   . GLY C 3 70  ? 88.328  120.429 154.741 1.00 158.01 ? 70  GLY L C   1 
ATOM   7709  O  O   . GLY C 3 70  ? 88.199  119.339 155.311 1.00 163.24 ? 70  GLY L O   1 
ATOM   7710  N  N   . SER C 3 71  ? 87.609  120.815 153.674 1.00 145.03 ? 71  SER L N   1 
ATOM   7711  C  CA  . SER C 3 71  ? 86.454  120.059 153.218 1.00 186.74 ? 71  SER L CA  1 
ATOM   7712  C  C   . SER C 3 71  ? 86.110  120.402 151.772 1.00 185.70 ? 71  SER L C   1 
ATOM   7713  O  O   . SER C 3 71  ? 86.581  121.397 151.234 1.00 150.52 ? 71  SER L O   1 
ATOM   7714  C  CB  . SER C 3 71  ? 85.265  120.310 154.132 1.00 300.60 ? 71  SER L CB  1 
ATOM   7715  O  OG  . SER C 3 71  ? 84.924  121.691 154.204 1.00 284.23 ? 71  SER L OG  1 
ATOM   7716  N  N   . GLY C 3 72  ? 85.263  119.564 151.168 1.00 198.23 ? 72  GLY L N   1 
ATOM   7717  C  CA  . GLY C 3 72  ? 84.862  119.693 149.775 1.00 196.67 ? 72  GLY L CA  1 
ATOM   7718  C  C   . GLY C 3 72  ? 85.200  118.429 148.992 1.00 169.09 ? 72  GLY L C   1 
ATOM   7719  O  O   . GLY C 3 72  ? 85.833  117.513 149.543 1.00 133.62 ? 72  GLY L O   1 
ATOM   7720  N  N   . SER C 3 73  ? 84.773  118.398 147.714 1.00 142.04 ? 73  SER L N   1 
ATOM   7721  C  CA  . SER C 3 73  ? 85.172  117.356 146.773 1.00 193.01 ? 73  SER L CA  1 
ATOM   7722  C  C   . SER C 3 73  ? 85.018  117.840 145.332 1.00 146.53 ? 73  SER L C   1 
ATOM   7723  O  O   . SER C 3 73  ? 84.349  118.809 145.086 1.00 130.62 ? 73  SER L O   1 
ATOM   7724  C  CB  . SER C 3 73  ? 84.410  116.063 147.016 1.00 248.50 ? 73  SER L CB  1 
ATOM   7725  O  OG  . SER C 3 73  ? 83.015  116.245 146.797 1.00 247.51 ? 73  SER L OG  1 
ATOM   7726  N  N   . GLY C 3 74  ? 85.649  117.130 144.388 1.00 170.29 ? 74  GLY L N   1 
ATOM   7727  C  CA  . GLY C 3 74  ? 85.515  117.406 142.970 1.00 190.64 ? 74  GLY L CA  1 
ATOM   7728  C  C   . GLY C 3 74  ? 86.316  118.639 142.577 1.00 158.62 ? 74  GLY L C   1 
ATOM   7729  O  O   . GLY C 3 74  ? 87.481  118.507 142.215 1.00 176.01 ? 74  GLY L O   1 
ATOM   7730  N  N   . THR C 3 75  ? 85.667  119.814 142.646 1.00 151.88 ? 75  THR L N   1 
ATOM   7731  C  CA  . THR C 3 75  ? 86.279  121.091 142.296 1.00 163.22 ? 75  THR L CA  1 
ATOM   7732  C  C   . THR C 3 75  ? 85.953  122.215 143.286 1.00 159.86 ? 75  THR L C   1 
ATOM   7733  O  O   . THR C 3 75  ? 86.664  123.203 143.279 1.00 178.30 ? 75  THR L O   1 
ATOM   7734  C  CB  . THR C 3 75  ? 85.910  121.541 140.867 1.00 170.92 ? 75  THR L CB  1 
ATOM   7735  O  OG1 . THR C 3 75  ? 84.523  121.861 140.763 1.00 242.99 ? 75  THR L OG1 1 
ATOM   7736  C  CG2 . THR C 3 75  ? 86.218  120.505 139.809 1.00 201.99 ? 75  THR L CG2 1 
ATOM   7737  N  N   . ASP C 3 76  ? 84.907  122.103 144.111 1.00 137.93 ? 76  ASP L N   1 
ATOM   7738  C  CA  . ASP C 3 76  ? 84.606  123.092 145.130 1.00 197.54 ? 76  ASP L CA  1 
ATOM   7739  C  C   . ASP C 3 76  ? 85.274  122.665 146.434 1.00 165.07 ? 76  ASP L C   1 
ATOM   7740  O  O   . ASP C 3 76  ? 84.860  121.700 147.063 1.00 146.28 ? 76  ASP L O   1 
ATOM   7741  C  CB  . ASP C 3 76  ? 83.092  123.270 145.324 1.00 329.55 ? 76  ASP L CB  1 
ATOM   7742  C  CG  . ASP C 3 76  ? 82.312  123.697 144.087 1.00 371.09 ? 76  ASP L CG  1 
ATOM   7743  O  OD1 . ASP C 3 76  ? 82.844  124.521 143.310 1.00 396.55 ? 76  ASP L OD1 1 
ATOM   7744  O  OD2 . ASP C 3 76  ? 81.168  123.205 143.910 1.00 367.53 ? 76  ASP L OD2 1 
ATOM   7745  N  N   . PHE C 3 77  ? 86.308  123.397 146.858 1.00 182.02 ? 77  PHE L N   1 
ATOM   7746  C  CA  . PHE C 3 77  ? 87.036  123.088 148.082 1.00 144.84 ? 77  PHE L CA  1 
ATOM   7747  C  C   . PHE C 3 77  ? 87.096  124.296 149.005 1.00 131.77 ? 77  PHE L C   1 
ATOM   7748  O  O   . PHE C 3 77  ? 87.204  125.436 148.534 1.00 118.66 ? 77  PHE L O   1 
ATOM   7749  C  CB  . PHE C 3 77  ? 88.475  122.709 147.751 1.00 157.27 ? 77  PHE L CB  1 
ATOM   7750  C  CG  . PHE C 3 77  ? 88.596  121.408 147.013 1.00 149.17 ? 77  PHE L CG  1 
ATOM   7751  C  CD1 . PHE C 3 77  ? 88.525  120.229 147.709 1.00 141.22 ? 77  PHE L CD1 1 
ATOM   7752  C  CD2 . PHE C 3 77  ? 88.785  121.365 145.636 1.00 136.44 ? 77  PHE L CD2 1 
ATOM   7753  C  CE1 . PHE C 3 77  ? 88.637  119.027 147.033 1.00 215.38 ? 77  PHE L CE1 1 
ATOM   7754  C  CE2 . PHE C 3 77  ? 88.889  120.159 144.975 1.00 121.08 ? 77  PHE L CE2 1 
ATOM   7755  C  CZ  . PHE C 3 77  ? 88.825  118.998 145.668 1.00 151.27 ? 77  PHE L CZ  1 
ATOM   7756  N  N   . THR C 3 78  ? 87.051  124.020 150.320 1.00 136.49 ? 78  THR L N   1 
ATOM   7757  C  CA  . THR C 3 78  ? 87.073  125.061 151.342 1.00 165.41 ? 78  THR L CA  1 
ATOM   7758  C  C   . THR C 3 78  ? 87.953  124.705 152.539 1.00 150.40 ? 78  THR L C   1 
ATOM   7759  O  O   . THR C 3 78  ? 87.837  123.636 153.139 1.00 140.19 ? 78  THR L O   1 
ATOM   7760  C  CB  . THR C 3 78  ? 85.679  125.348 151.886 1.00 239.15 ? 78  THR L CB  1 
ATOM   7761  O  OG1 . THR C 3 78  ? 85.108  124.108 152.308 1.00 307.49 ? 78  THR L OG1 1 
ATOM   7762  C  CG2 . THR C 3 78  ? 84.802  126.015 150.854 1.00 278.10 ? 78  THR L CG2 1 
ATOM   7763  N  N   . LEU C 3 79  ? 88.849  125.640 152.867 1.00 137.25 ? 79  LEU L N   1 
ATOM   7764  C  CA  . LEU C 3 79  ? 89.498  125.668 154.158 1.00 139.58 ? 79  LEU L CA  1 
ATOM   7765  C  C   . LEU C 3 79  ? 88.675  126.601 155.044 1.00 191.48 ? 79  LEU L C   1 
ATOM   7766  O  O   . LEU C 3 79  ? 88.348  127.718 154.625 1.00 174.85 ? 79  LEU L O   1 
ATOM   7767  C  CB  . LEU C 3 79  ? 90.944  126.159 153.999 1.00 98.50  ? 79  LEU L CB  1 
ATOM   7768  C  CG  . LEU C 3 79  ? 91.651  126.552 155.300 1.00 132.27 ? 79  LEU L CG  1 
ATOM   7769  C  CD1 . LEU C 3 79  ? 91.868  125.358 156.222 1.00 156.77 ? 79  LEU L CD1 1 
ATOM   7770  C  CD2 . LEU C 3 79  ? 92.959  127.225 155.059 1.00 113.29 ? 79  LEU L CD2 1 
ATOM   7771  N  N   . THR C 3 80  ? 88.357  126.136 156.265 1.00 210.58 ? 80  THR L N   1 
ATOM   7772  C  CA  . THR C 3 80  ? 87.609  126.931 157.229 1.00 191.97 ? 80  THR L CA  1 
ATOM   7773  C  C   . THR C 3 80  ? 88.389  127.019 158.533 1.00 165.46 ? 80  THR L C   1 
ATOM   7774  O  O   . THR C 3 80  ? 89.071  126.060 158.895 1.00 176.92 ? 80  THR L O   1 
ATOM   7775  C  CB  . THR C 3 80  ? 86.219  126.349 157.469 1.00 255.66 ? 80  THR L CB  1 
ATOM   7776  O  OG1 . THR C 3 80  ? 86.346  125.067 158.092 1.00 266.67 ? 80  THR L OG1 1 
ATOM   7777  C  CG2 . THR C 3 80  ? 85.433  126.231 156.181 1.00 289.87 ? 80  THR L CG2 1 
ATOM   7778  N  N   . ILE C 3 81  ? 88.302  128.175 159.200 1.00 150.50 ? 81  ILE L N   1 
ATOM   7779  C  CA  . ILE C 3 81  ? 88.912  128.363 160.506 1.00 197.70 ? 81  ILE L CA  1 
ATOM   7780  C  C   . ILE C 3 81  ? 87.726  128.566 161.435 1.00 241.43 ? 81  ILE L C   1 
ATOM   7781  O  O   . ILE C 3 81  ? 86.983  129.504 161.229 1.00 221.35 ? 81  ILE L O   1 
ATOM   7782  C  CB  . ILE C 3 81  ? 89.937  129.525 160.566 1.00 210.69 ? 81  ILE L CB  1 
ATOM   7783  C  CG1 . ILE C 3 81  ? 90.865  129.586 159.337 1.00 230.87 ? 81  ILE L CG1 1 
ATOM   7784  C  CG2 . ILE C 3 81  ? 90.741  129.441 161.854 1.00 158.52 ? 81  ILE L CG2 1 
ATOM   7785  C  CD1 . ILE C 3 81  ? 91.851  130.778 159.302 1.00 217.67 ? 81  ILE L CD1 1 
ATOM   7786  N  N   . SER C 3 82  ? 87.546  127.685 162.427 1.00 283.95 ? 82  SER L N   1 
ATOM   7787  C  CA  . SER C 3 82  ? 86.347  127.659 163.262 1.00 294.73 ? 82  SER L CA  1 
ATOM   7788  C  C   . SER C 3 82  ? 86.230  128.889 164.159 1.00 256.45 ? 82  SER L C   1 
ATOM   7789  O  O   . SER C 3 82  ? 85.113  129.305 164.462 1.00 198.16 ? 82  SER L O   1 
ATOM   7790  C  CB  . SER C 3 82  ? 86.306  126.411 164.105 1.00 284.56 ? 82  SER L CB  1 
ATOM   7791  O  OG  . SER C 3 82  ? 86.235  125.262 163.280 1.00 264.83 ? 82  SER L OG  1 
ATOM   7792  N  N   . SER C 3 83  ? 87.376  129.440 164.586 1.00 256.70 ? 83  SER L N   1 
ATOM   7793  C  CA  . SER C 3 83  ? 87.399  130.571 165.502 1.00 282.72 ? 83  SER L CA  1 
ATOM   7794  C  C   . SER C 3 83  ? 88.759  131.272 165.429 1.00 229.39 ? 83  SER L C   1 
ATOM   7795  O  O   . SER C 3 83  ? 89.686  130.918 166.177 1.00 158.23 ? 83  SER L O   1 
ATOM   7796  C  CB  . SER C 3 83  ? 87.056  130.132 166.917 1.00 345.76 ? 83  SER L CB  1 
ATOM   7797  O  OG  . SER C 3 83  ? 86.876  131.249 167.779 1.00 365.90 ? 83  SER L OG  1 
ATOM   7798  N  N   . VAL C 3 84  ? 88.827  132.264 164.517 1.00 161.02 ? 84  VAL L N   1 
ATOM   7799  C  CA  . VAL C 3 84  ? 90.018  133.030 164.160 1.00 152.60 ? 84  VAL L CA  1 
ATOM   7800  C  C   . VAL C 3 84  ? 90.702  133.641 165.379 1.00 137.98 ? 84  VAL L C   1 
ATOM   7801  O  O   . VAL C 3 84  ? 90.045  134.293 166.195 1.00 209.02 ? 84  VAL L O   1 
ATOM   7802  C  CB  . VAL C 3 84  ? 89.643  134.130 163.147 1.00 160.13 ? 84  VAL L CB  1 
ATOM   7803  C  CG1 . VAL C 3 84  ? 90.626  135.312 163.095 1.00 156.12 ? 84  VAL L CG1 1 
ATOM   7804  C  CG2 . VAL C 3 84  ? 89.434  133.492 161.778 1.00 194.43 ? 84  VAL L CG2 1 
ATOM   7805  N  N   . GLN C 3 85  ? 92.024  133.429 165.462 1.00 142.58 ? 85  GLN L N   1 
ATOM   7806  C  CA  . GLN C 3 85  ? 92.862  134.068 166.463 1.00 195.03 ? 85  GLN L CA  1 
ATOM   7807  C  C   . GLN C 3 85  ? 93.690  135.181 165.816 1.00 190.14 ? 85  GLN L C   1 
ATOM   7808  O  O   . GLN C 3 85  ? 93.855  135.240 164.605 1.00 174.20 ? 85  GLN L O   1 
ATOM   7809  C  CB  . GLN C 3 85  ? 93.690  132.997 167.174 1.00 173.13 ? 85  GLN L CB  1 
ATOM   7810  C  CG  . GLN C 3 85  ? 92.790  131.928 167.788 1.00 178.11 ? 85  GLN L CG  1 
ATOM   7811  C  CD  . GLN C 3 85  ? 93.397  131.130 168.918 1.00 249.54 ? 85  GLN L CD  1 
ATOM   7812  O  OE1 . GLN C 3 85  ? 94.415  131.490 169.522 1.00 191.50 ? 85  GLN L OE1 1 
ATOM   7813  N  NE2 . GLN C 3 85  ? 92.748  130.013 169.218 1.00 277.32 ? 85  GLN L NE2 1 
ATOM   7814  N  N   . ALA C 3 86  ? 94.214  136.077 166.654 1.00 234.11 ? 86  ALA L N   1 
ATOM   7815  C  CA  . ALA C 3 86  ? 95.043  137.175 166.185 1.00 232.86 ? 86  ALA L CA  1 
ATOM   7816  C  C   . ALA C 3 86  ? 96.290  136.646 165.475 1.00 224.86 ? 86  ALA L C   1 
ATOM   7817  O  O   . ALA C 3 86  ? 96.828  137.339 164.608 1.00 252.93 ? 86  ALA L O   1 
ATOM   7818  C  CB  . ALA C 3 86  ? 95.406  138.060 167.356 1.00 289.39 ? 86  ALA L CB  1 
ATOM   7819  N  N   . GLU C 3 87  ? 96.752  135.429 165.838 1.00 202.94 ? 87  GLU L N   1 
ATOM   7820  C  CA  . GLU C 3 87  ? 97.946  134.846 165.233 1.00 231.20 ? 87  GLU L CA  1 
ATOM   7821  C  C   . GLU C 3 87  ? 97.709  134.343 163.806 1.00 181.29 ? 87  GLU L C   1 
ATOM   7822  O  O   . GLU C 3 87  ? 98.679  133.959 163.172 1.00 181.69 ? 87  GLU L O   1 
ATOM   7823  C  CB  . GLU C 3 87  ? 98.536  133.732 166.110 1.00 267.14 ? 87  GLU L CB  1 
ATOM   7824  C  CG  . GLU C 3 87  ? 97.682  132.488 166.279 1.00 297.93 ? 87  GLU L CG  1 
ATOM   7825  C  CD  . GLU C 3 87  ? 98.273  131.399 167.164 1.00 388.60 ? 87  GLU L CD  1 
ATOM   7826  O  OE1 . GLU C 3 87  ? 98.987  131.733 168.132 1.00 450.31 ? 87  GLU L OE1 1 
ATOM   7827  O  OE2 . GLU C 3 87  ? 97.999  130.206 166.887 1.00 414.97 ? 87  GLU L OE2 1 
ATOM   7828  N  N   . ASP C 3 88  ? 96.467  134.348 163.299 1.00 183.12 ? 88  ASP L N   1 
ATOM   7829  C  CA  . ASP C 3 88  ? 96.123  133.692 162.044 1.00 156.22 ? 88  ASP L CA  1 
ATOM   7830  C  C   . ASP C 3 88  ? 96.202  134.608 160.823 1.00 120.03 ? 88  ASP L C   1 
ATOM   7831  O  O   . ASP C 3 88  ? 96.023  134.092 159.737 1.00 117.34 ? 88  ASP L O   1 
ATOM   7832  C  CB  . ASP C 3 88  ? 94.723  133.071 162.123 1.00 177.41 ? 88  ASP L CB  1 
ATOM   7833  C  CG  . ASP C 3 88  ? 94.618  131.880 163.056 1.00 190.09 ? 88  ASP L CG  1 
ATOM   7834  O  OD1 . ASP C 3 88  ? 95.617  131.143 163.149 1.00 186.17 ? 88  ASP L OD1 1 
ATOM   7835  O  OD2 . ASP C 3 88  ? 93.532  131.682 163.673 1.00 212.76 ? 88  ASP L OD2 1 
ATOM   7836  N  N   . LEU C 3 89  ? 96.489  135.909 160.941 1.00 123.54 ? 89  LEU L N   1 
ATOM   7837  C  CA  . LEU C 3 89  ? 96.549  136.757 159.756 1.00 126.05 ? 89  LEU L CA  1 
ATOM   7838  C  C   . LEU C 3 89  ? 97.754  136.374 158.883 1.00 145.98 ? 89  LEU L C   1 
ATOM   7839  O  O   . LEU C 3 89  ? 98.893  136.276 159.381 1.00 136.47 ? 89  LEU L O   1 
ATOM   7840  C  CB  . LEU C 3 89  ? 96.604  138.218 160.204 1.00 179.95 ? 89  LEU L CB  1 
ATOM   7841  C  CG  . LEU C 3 89  ? 97.925  138.772 160.745 1.00 190.42 ? 89  LEU L CG  1 
ATOM   7842  C  CD1 . LEU C 3 89  ? 98.675  139.495 159.641 1.00 224.15 ? 89  LEU L CD1 1 
ATOM   7843  C  CD2 . LEU C 3 89  ? 97.705  139.735 161.904 1.00 248.33 ? 89  LEU L CD2 1 
ATOM   7844  N  N   . ALA C 3 90  ? 97.481  136.157 157.575 1.00 133.40 ? 90  ALA L N   1 
ATOM   7845  C  CA  . ALA C 3 90  ? 98.366  135.463 156.628 1.00 140.52 ? 90  ALA L CA  1 
ATOM   7846  C  C   . ALA C 3 90  ? 97.802  135.526 155.214 1.00 121.23 ? 90  ALA L C   1 
ATOM   7847  O  O   . ALA C 3 90  ? 96.667  135.961 155.051 1.00 142.60 ? 90  ALA L O   1 
ATOM   7848  C  CB  . ALA C 3 90  ? 98.536  134.015 157.009 1.00 128.83 ? 90  ALA L CB  1 
ATOM   7849  N  N   . LEU C 3 91  ? 98.582  135.107 154.204 1.00 130.35 ? 91  LEU L N   1 
ATOM   7850  C  CA  . LEU C 3 91  ? 98.016  134.685 152.923 1.00 125.28 ? 91  LEU L CA  1 
ATOM   7851  C  C   . LEU C 3 91  ? 97.888  133.186 153.008 1.00 123.46 ? 91  LEU L C   1 
ATOM   7852  O  O   . LEU C 3 91  ? 98.785  132.542 153.538 1.00 165.88 ? 91  LEU L O   1 
ATOM   7853  C  CB  . LEU C 3 91  ? 98.871  135.037 151.699 1.00 128.29 ? 91  LEU L CB  1 
ATOM   7854  C  CG  . LEU C 3 91  ? 99.057  136.520 151.395 1.00 219.78 ? 91  LEU L CG  1 
ATOM   7855  C  CD1 . LEU C 3 91  ? 100.103 137.170 152.313 1.00 241.81 ? 91  LEU L CD1 1 
ATOM   7856  C  CD2 . LEU C 3 91  ? 99.417  136.712 149.927 1.00 266.93 ? 91  LEU L CD2 1 
ATOM   7857  N  N   . TYR C 3 92  ? 96.790  132.657 152.475 1.00 127.88 ? 92  TYR L N   1 
ATOM   7858  C  CA  . TYR C 3 92  ? 96.555  131.223 152.417 1.00 125.85 ? 92  TYR L CA  1 
ATOM   7859  C  C   . TYR C 3 92  ? 96.516  130.823 150.956 1.00 89.39  ? 92  TYR L C   1 
ATOM   7860  O  O   . TYR C 3 92  ? 95.737  131.400 150.219 1.00 149.12 ? 92  TYR L O   1 
ATOM   7861  C  CB  . TYR C 3 92  ? 95.239  130.818 153.103 1.00 108.10 ? 92  TYR L CB  1 
ATOM   7862  C  CG  . TYR C 3 92  ? 95.280  131.020 154.611 1.00 112.71 ? 92  TYR L CG  1 
ATOM   7863  C  CD1 . TYR C 3 92  ? 95.214  132.274 155.170 1.00 119.46 ? 92  TYR L CD1 1 
ATOM   7864  C  CD2 . TYR C 3 92  ? 95.393  129.950 155.483 1.00 134.32 ? 92  TYR L CD2 1 
ATOM   7865  C  CE1 . TYR C 3 92  ? 95.264  132.446 156.541 1.00 170.37 ? 92  TYR L CE1 1 
ATOM   7866  C  CE2 . TYR C 3 92  ? 95.434  130.105 156.859 1.00 126.24 ? 92  TYR L CE2 1 
ATOM   7867  C  CZ  . TYR C 3 92  ? 95.385  131.359 157.394 1.00 124.95 ? 92  TYR L CZ  1 
ATOM   7868  O  OH  . TYR C 3 92  ? 95.426  131.488 158.750 1.00 116.16 ? 92  TYR L OH  1 
ATOM   7869  N  N   . TYR C 3 93  ? 97.321  129.844 150.540 1.00 79.95  ? 93  TYR L N   1 
ATOM   7870  C  CA  . TYR C 3 93  ? 97.261  129.326 149.177 1.00 95.08  ? 93  TYR L CA  1 
ATOM   7871  C  C   . TYR C 3 93  ? 96.697  127.906 149.131 1.00 96.50  ? 93  TYR L C   1 
ATOM   7872  O  O   . TYR C 3 93  ? 97.023  127.066 149.976 1.00 61.20  ? 93  TYR L O   1 
ATOM   7873  C  CB  . TYR C 3 93  ? 98.670  129.282 148.613 1.00 104.71 ? 93  TYR L CB  1 
ATOM   7874  C  CG  . TYR C 3 93  ? 99.490  130.556 148.714 1.00 97.76  ? 93  TYR L CG  1 
ATOM   7875  C  CD1 . TYR C 3 93  ? 99.411  131.532 147.769 1.00 112.25 ? 93  TYR L CD1 1 
ATOM   7876  C  CD2 . TYR C 3 93  ? 100.346 130.771 149.754 1.00 117.10 ? 93  TYR L CD2 1 
ATOM   7877  C  CE1 . TYR C 3 93  ? 100.176 132.676 147.855 1.00 107.64 ? 93  TYR L CE1 1 
ATOM   7878  C  CE2 . TYR C 3 93  ? 101.093 131.910 149.863 1.00 136.28 ? 93  TYR L CE2 1 
ATOM   7879  C  CZ  . TYR C 3 93  ? 101.025 132.883 148.909 1.00 113.86 ? 93  TYR L CZ  1 
ATOM   7880  O  OH  . TYR C 3 93  ? 101.828 133.984 149.110 1.00 131.11 ? 93  TYR L OH  1 
ATOM   7881  N  N   . CYS C 3 94  ? 95.834  127.637 148.140 1.00 93.21  ? 94  CYS L N   1 
ATOM   7882  C  CA  . CYS C 3 94  ? 95.507  126.253 147.853 1.00 92.72  ? 94  CYS L CA  1 
ATOM   7883  C  C   . CYS C 3 94  ? 96.497  125.758 146.814 1.00 86.24  ? 94  CYS L C   1 
ATOM   7884  O  O   . CYS C 3 94  ? 96.941  126.534 146.014 1.00 94.27  ? 94  CYS L O   1 
ATOM   7885  C  CB  . CYS C 3 94  ? 94.059  126.057 147.411 1.00 126.02 ? 94  CYS L CB  1 
ATOM   7886  S  SG  . CYS C 3 94  ? 93.578  126.752 145.811 1.00 187.84 ? 94  CYS L SG  1 
ATOM   7887  N  N   . GLN C 3 95  ? 96.851  124.466 146.830 1.00 101.20 ? 95  GLN L N   1 
ATOM   7888  C  CA  . GLN C 3 95  ? 97.660  123.790 145.812 1.00 82.36  ? 95  GLN L CA  1 
ATOM   7889  C  C   . GLN C 3 95  ? 97.038  122.445 145.480 1.00 78.96  ? 95  GLN L C   1 
ATOM   7890  O  O   . GLN C 3 95  ? 96.578  121.754 146.405 1.00 89.09  ? 95  GLN L O   1 
ATOM   7891  C  CB  . GLN C 3 95  ? 99.021  123.494 146.399 1.00 98.37  ? 95  GLN L CB  1 
ATOM   7892  C  CG  . GLN C 3 95  ? 100.057 122.964 145.422 1.00 78.59  ? 95  GLN L CG  1 
ATOM   7893  C  CD  . GLN C 3 95  ? 100.969 121.942 146.050 1.00 95.28  ? 95  GLN L CD  1 
ATOM   7894  O  OE1 . GLN C 3 95  ? 101.670 122.149 147.048 1.00 86.29  ? 95  GLN L OE1 1 
ATOM   7895  N  NE2 . GLN C 3 95  ? 100.994 120.773 145.448 1.00 144.18 ? 95  GLN L NE2 1 
ATOM   7896  N  N   . GLN C 3 96  ? 96.985  122.104 144.181 1.00 78.24  ? 96  GLN L N   1 
ATOM   7897  C  CA  . GLN C 3 96  ? 96.631  120.751 143.809 1.00 96.30  ? 96  GLN L CA  1 
ATOM   7898  C  C   . GLN C 3 96  ? 97.882  119.890 143.927 1.00 64.80  ? 96  GLN L C   1 
ATOM   7899  O  O   . GLN C 3 96  ? 98.969  120.361 143.612 1.00 98.08  ? 96  GLN L O   1 
ATOM   7900  C  CB  . GLN C 3 96  ? 95.968  120.657 142.416 1.00 85.93  ? 96  GLN L CB  1 
ATOM   7901  C  CG  . GLN C 3 96  ? 96.840  120.112 141.254 1.00 55.02  ? 96  GLN L CG  1 
ATOM   7902  C  CD  . GLN C 3 96  ? 97.644  121.251 140.756 1.00 102.47 ? 96  GLN L CD  1 
ATOM   7903  O  OE1 . GLN C 3 96  ? 97.749  122.271 141.424 1.00 137.24 ? 96  GLN L OE1 1 
ATOM   7904  N  NE2 . GLN C 3 96  ? 98.220  121.125 139.576 1.00 134.06 ? 96  GLN L NE2 1 
ATOM   7905  N  N   . HIS C 3 97  ? 97.693  118.631 144.339 1.00 60.35  ? 97  HIS L N   1 
ATOM   7906  C  CA  . HIS C 3 97  ? 98.710  117.660 144.060 1.00 81.28  ? 97  HIS L CA  1 
ATOM   7907  C  C   . HIS C 3 97  ? 98.238  116.473 143.233 1.00 60.08  ? 97  HIS L C   1 
ATOM   7908  O  O   . HIS C 3 97  ? 98.717  115.374 143.400 1.00 69.24  ? 97  HIS L O   1 
ATOM   7909  C  CB  . HIS C 3 97  ? 99.450  117.380 145.360 1.00 82.35  ? 97  HIS L CB  1 
ATOM   7910  C  CG  . HIS C 3 97  ? 98.671  117.039 146.475 1.00 73.90  ? 97  HIS L CG  1 
ATOM   7911  N  ND1 . HIS C 3 97  ? 98.371  117.933 147.451 1.00 90.94  ? 97  HIS L ND1 1 
ATOM   7912  C  CD2 . HIS C 3 97  ? 98.204  115.899 146.772 1.00 85.71  ? 97  HIS L CD2 1 
ATOM   7913  C  CE1 . HIS C 3 97  ? 97.690  117.267 148.352 1.00 150.37 ? 97  HIS L CE1 1 
ATOM   7914  N  NE2 . HIS C 3 97  ? 97.582  116.027 147.954 1.00 112.09 ? 97  HIS L NE2 1 
ATOM   7915  N  N   . TYR C 3 98  ? 97.369  116.711 142.311 1.00 55.06  ? 98  TYR L N   1 
ATOM   7916  C  CA  . TYR C 3 98  ? 96.980  115.652 141.442 1.00 70.14  ? 98  TYR L CA  1 
ATOM   7917  C  C   . TYR C 3 98  ? 97.894  115.656 140.250 1.00 70.95  ? 98  TYR L C   1 
ATOM   7918  O  O   . TYR C 3 98  ? 97.909  114.597 139.607 1.00 120.13 ? 98  TYR L O   1 
ATOM   7919  C  CB  . TYR C 3 98  ? 95.501  115.849 141.112 1.00 84.82  ? 98  TYR L CB  1 
ATOM   7920  C  CG  . TYR C 3 98  ? 94.850  114.845 140.198 1.00 71.34  ? 98  TYR L CG  1 
ATOM   7921  C  CD1 . TYR C 3 98  ? 94.903  115.004 138.810 1.00 83.60  ? 98  TYR L CD1 1 
ATOM   7922  C  CD2 . TYR C 3 98  ? 94.210  113.763 140.738 1.00 65.90  ? 98  TYR L CD2 1 
ATOM   7923  C  CE1 . TYR C 3 98  ? 94.282  114.077 137.985 1.00 139.99 ? 98  TYR L CE1 1 
ATOM   7924  C  CE2 . TYR C 3 98  ? 93.588  112.820 139.928 1.00 134.24 ? 98  TYR L CE2 1 
ATOM   7925  C  CZ  . TYR C 3 98  ? 93.617  112.973 138.546 1.00 209.25 ? 98  TYR L CZ  1 
ATOM   7926  O  OH  . TYR C 3 98  ? 92.982  111.988 137.816 1.00 216.91 ? 98  TYR L OH  1 
ATOM   7927  N  N   . THR C 3 99  ? 98.595  116.741 139.923 1.00 54.45  ? 99  THR L N   1 
ATOM   7928  C  CA  . THR C 3 99  ? 99.677  116.515 138.966 1.00 80.81  ? 99  THR L CA  1 
ATOM   7929  C  C   . THR C 3 99  ? 100.980 117.173 139.372 1.00 93.60  ? 99  THR L C   1 
ATOM   7930  O  O   . THR C 3 99  ? 100.999 118.178 140.053 1.00 101.22 ? 99  THR L O   1 
ATOM   7931  C  CB  . THR C 3 99  ? 99.414  117.023 137.556 1.00 106.12 ? 99  THR L CB  1 
ATOM   7932  O  OG1 . THR C 3 99  ? 99.278  118.436 137.655 1.00 210.11 ? 99  THR L OG1 1 
ATOM   7933  C  CG2 . THR C 3 99  ? 98.136  116.466 136.973 1.00 159.38 ? 99  THR L CG2 1 
ATOM   7934  N  N   . ILE C 3 100 ? 102.077 116.580 138.919 1.00 90.59  ? 100 ILE L N   1 
ATOM   7935  C  CA  . ILE C 3 100 ? 103.382 117.220 139.050 1.00 76.89  ? 100 ILE L CA  1 
ATOM   7936  C  C   . ILE C 3 100 ? 103.736 117.612 137.641 1.00 58.85  ? 100 ILE L C   1 
ATOM   7937  O  O   . ILE C 3 100 ? 103.695 116.719 136.811 1.00 51.24  ? 100 ILE L O   1 
ATOM   7938  C  CB  . ILE C 3 100 ? 104.512 116.421 139.758 1.00 68.01  ? 100 ILE L CB  1 
ATOM   7939  C  CG1 . ILE C 3 100 ? 105.767 116.374 138.895 1.00 56.89  ? 100 ILE L CG1 1 
ATOM   7940  C  CG2 . ILE C 3 100 ? 104.146 115.028 140.207 1.00 64.41  ? 100 ILE L CG2 1 
ATOM   7941  C  CD1 . ILE C 3 100 ? 106.843 115.803 139.739 1.00 95.27  ? 100 ILE L CD1 1 
ATOM   7942  N  N   . PRO C 3 101 ? 104.073 118.907 137.348 1.00 77.57  ? 101 PRO L N   1 
ATOM   7943  C  CA  . PRO C 3 101 ? 104.256 119.977 138.340 1.00 65.65  ? 101 PRO L CA  1 
ATOM   7944  C  C   . PRO C 3 101 ? 102.933 120.423 138.980 1.00 69.32  ? 101 PRO L C   1 
ATOM   7945  O  O   . PRO C 3 101 ? 101.876 120.485 138.321 1.00 63.21  ? 101 PRO L O   1 
ATOM   7946  C  CB  . PRO C 3 101 ? 104.693 121.129 137.447 1.00 84.06  ? 101 PRO L CB  1 
ATOM   7947  C  CG  . PRO C 3 101 ? 104.024 120.910 136.076 1.00 91.86  ? 101 PRO L CG  1 
ATOM   7948  C  CD  . PRO C 3 101 ? 104.256 119.419 135.970 1.00 102.14 ? 101 PRO L CD  1 
ATOM   7949  N  N   . PRO C 3 102 ? 102.932 120.780 140.266 1.00 56.63  ? 102 PRO L N   1 
ATOM   7950  C  CA  . PRO C 3 102 ? 101.758 121.340 140.899 1.00 75.42  ? 102 PRO L CA  1 
ATOM   7951  C  C   . PRO C 3 102 ? 101.537 122.783 140.495 1.00 79.30  ? 102 PRO L C   1 
ATOM   7952  O  O   . PRO C 3 102 ? 102.408 123.367 139.876 1.00 133.58 ? 102 PRO L O   1 
ATOM   7953  C  CB  . PRO C 3 102 ? 102.150 121.233 142.391 1.00 60.00  ? 102 PRO L CB  1 
ATOM   7954  C  CG  . PRO C 3 102 ? 103.559 121.361 142.427 1.00 49.13  ? 102 PRO L CG  1 
ATOM   7955  C  CD  . PRO C 3 102 ? 104.043 120.692 141.172 1.00 47.35  ? 102 PRO L CD  1 
ATOM   7956  N  N   . THR C 3 103 ? 100.401 123.359 140.895 1.00 95.55  ? 103 THR L N   1 
ATOM   7957  C  CA  . THR C 3 103 ? 100.096 124.768 140.696 1.00 110.69 ? 103 THR L CA  1 
ATOM   7958  C  C   . THR C 3 103 ? 99.331  125.326 141.889 1.00 85.25  ? 103 THR L C   1 
ATOM   7959  O  O   . THR C 3 103 ? 98.661  124.614 142.618 1.00 74.70  ? 103 THR L O   1 
ATOM   7960  C  CB  . THR C 3 103 ? 99.276  124.953 139.422 1.00 152.55 ? 103 THR L CB  1 
ATOM   7961  O  OG1 . THR C 3 103 ? 98.229  123.992 139.408 1.00 107.27 ? 103 THR L OG1 1 
ATOM   7962  C  CG2 . THR C 3 103 ? 100.053 124.738 138.143 1.00 228.79 ? 103 THR L CG2 1 
ATOM   7963  N  N   . PHE C 3 104 ? 99.399  126.621 142.089 1.00 85.79  ? 104 PHE L N   1 
ATOM   7964  C  CA  . PHE C 3 104 ? 98.824  127.192 143.284 1.00 108.23 ? 104 PHE L CA  1 
ATOM   7965  C  C   . PHE C 3 104 ? 97.815  128.314 142.972 1.00 135.20 ? 104 PHE L C   1 
ATOM   7966  O  O   . PHE C 3 104 ? 97.911  129.020 141.968 1.00 140.56 ? 104 PHE L O   1 
ATOM   7967  C  CB  . PHE C 3 104 ? 99.985  127.786 144.071 1.00 150.48 ? 104 PHE L CB  1 
ATOM   7968  C  CG  . PHE C 3 104 ? 101.087 126.881 144.551 1.00 97.68  ? 104 PHE L CG  1 
ATOM   7969  C  CD1 . PHE C 3 104 ? 102.080 126.449 143.695 1.00 81.04  ? 104 PHE L CD1 1 
ATOM   7970  C  CD2 . PHE C 3 104 ? 101.136 126.531 145.896 1.00 83.12  ? 104 PHE L CD2 1 
ATOM   7971  C  CE1 . PHE C 3 104 ? 103.062 125.649 144.212 1.00 90.10  ? 104 PHE L CE1 1 
ATOM   7972  C  CE2 . PHE C 3 104 ? 102.141 125.746 146.411 1.00 62.31  ? 104 PHE L CE2 1 
ATOM   7973  C  CZ  . PHE C 3 104 ? 103.097 125.329 145.557 1.00 70.10  ? 104 PHE L CZ  1 
ATOM   7974  N  N   . GLY C 3 105 ? 96.855  128.507 143.882 1.00 134.53 ? 105 GLY L N   1 
ATOM   7975  C  CA  . GLY C 3 105 ? 96.030  129.696 143.936 1.00 164.83 ? 105 GLY L CA  1 
ATOM   7976  C  C   . GLY C 3 105 ? 96.799  131.000 144.144 1.00 120.51 ? 105 GLY L C   1 
ATOM   7977  O  O   . GLY C 3 105 ? 97.913  131.041 144.599 1.00 114.83 ? 105 GLY L O   1 
ATOM   7978  N  N   . GLY C 3 106 ? 96.155  132.098 143.776 1.00 156.74 ? 106 GLY L N   1 
ATOM   7979  C  CA  . GLY C 3 106 ? 96.715  133.414 143.978 1.00 160.57 ? 106 GLY L CA  1 
ATOM   7980  C  C   . GLY C 3 106 ? 96.584  133.865 145.422 1.00 127.56 ? 106 GLY L C   1 
ATOM   7981  O  O   . GLY C 3 106 ? 97.115  134.926 145.760 1.00 210.65 ? 106 GLY L O   1 
ATOM   7982  N  N   . GLY C 3 107 ? 95.889  133.095 146.253 1.00 99.55  ? 107 GLY L N   1 
ATOM   7983  C  CA  . GLY C 3 107 ? 95.986  133.279 147.701 1.00 156.34 ? 107 GLY L CA  1 
ATOM   7984  C  C   . GLY C 3 107 ? 94.974  134.280 148.280 1.00 142.90 ? 107 GLY L C   1 
ATOM   7985  O  O   . GLY C 3 107 ? 94.681  135.308 147.670 1.00 168.34 ? 107 GLY L O   1 
ATOM   7986  N  N   . THR C 3 108 ? 94.447  133.962 149.467 1.00 132.87 ? 108 THR L N   1 
ATOM   7987  C  CA  . THR C 3 108 ? 93.491  134.788 150.185 1.00 156.05 ? 108 THR L CA  1 
ATOM   7988  C  C   . THR C 3 108 ? 94.217  135.491 151.312 1.00 135.72 ? 108 THR L C   1 
ATOM   7989  O  O   . THR C 3 108 ? 94.773  134.794 152.158 1.00 199.88 ? 108 THR L O   1 
ATOM   7990  C  CB  . THR C 3 108 ? 92.362  133.942 150.793 1.00 176.75 ? 108 THR L CB  1 
ATOM   7991  O  OG1 . THR C 3 108 ? 91.543  133.389 149.761 1.00 171.40 ? 108 THR L OG1 1 
ATOM   7992  C  CG2 . THR C 3 108 ? 91.454  134.715 151.728 1.00 200.36 ? 108 THR L CG2 1 
ATOM   7993  N  N   . LYS C 3 109 ? 94.189  136.833 151.333 1.00 123.31 ? 109 LYS L N   1 
ATOM   7994  C  CA  . LYS C 3 109 ? 94.754  137.610 152.436 1.00 136.88 ? 109 LYS L CA  1 
ATOM   7995  C  C   . LYS C 3 109 ? 93.724  137.714 153.566 1.00 117.76 ? 109 LYS L C   1 
ATOM   7996  O  O   . LYS C 3 109 ? 92.739  138.417 153.445 1.00 150.98 ? 109 LYS L O   1 
ATOM   7997  C  CB  . LYS C 3 109 ? 95.223  138.957 151.878 1.00 149.24 ? 109 LYS L CB  1 
ATOM   7998  C  CG  . LYS C 3 109 ? 95.752  139.959 152.894 1.00 189.67 ? 109 LYS L CG  1 
ATOM   7999  C  CD  . LYS C 3 109 ? 97.094  139.576 153.469 1.00 230.08 ? 109 LYS L CD  1 
ATOM   8000  C  CE  . LYS C 3 109 ? 97.631  140.601 154.444 1.00 290.87 ? 109 LYS L CE  1 
ATOM   8001  N  NZ  . LYS C 3 109 ? 98.667  140.022 155.335 1.00 300.86 ? 109 LYS L NZ  1 
ATOM   8002  N  N   . LEU C 3 110 ? 93.928  136.994 154.664 1.00 122.41 ? 110 LEU L N   1 
ATOM   8003  C  CA  . LEU C 3 110 ? 93.095  137.155 155.844 1.00 130.19 ? 110 LEU L CA  1 
ATOM   8004  C  C   . LEU C 3 110 ? 93.610  138.395 156.570 1.00 148.73 ? 110 LEU L C   1 
ATOM   8005  O  O   . LEU C 3 110 ? 94.812  138.546 156.730 1.00 118.11 ? 110 LEU L O   1 
ATOM   8006  C  CB  . LEU C 3 110 ? 93.157  135.878 156.698 1.00 141.03 ? 110 LEU L CB  1 
ATOM   8007  C  CG  . LEU C 3 110 ? 92.686  135.947 158.151 1.00 124.56 ? 110 LEU L CG  1 
ATOM   8008  C  CD1 . LEU C 3 110 ? 91.245  136.352 158.215 1.00 198.53 ? 110 LEU L CD1 1 
ATOM   8009  C  CD2 . LEU C 3 110 ? 92.795  134.590 158.794 1.00 113.89 ? 110 LEU L CD2 1 
ATOM   8010  N  N   . GLU C 3 111 ? 92.676  139.272 156.978 1.00 190.05 ? 111 GLU L N   1 
ATOM   8011  C  CA  . GLU C 3 111 ? 92.938  140.476 157.756 1.00 180.41 ? 111 GLU L CA  1 
ATOM   8012  C  C   . GLU C 3 111 ? 92.050  140.456 158.998 1.00 164.29 ? 111 GLU L C   1 
ATOM   8013  O  O   . GLU C 3 111 ? 90.974  139.872 159.002 1.00 214.94 ? 111 GLU L O   1 
ATOM   8014  C  CB  . GLU C 3 111 ? 92.629  141.721 156.923 1.00 197.57 ? 111 GLU L CB  1 
ATOM   8015  C  CG  . GLU C 3 111 ? 93.386  141.798 155.596 1.00 263.84 ? 111 GLU L CG  1 
ATOM   8016  C  CD  . GLU C 3 111 ? 92.832  142.827 154.619 1.00 366.41 ? 111 GLU L CD  1 
ATOM   8017  O  OE1 . GLU C 3 111 ? 92.453  143.924 155.075 1.00 437.94 ? 111 GLU L OE1 1 
ATOM   8018  O  OE2 . GLU C 3 111 ? 92.785  142.537 153.402 1.00 415.42 ? 111 GLU L OE2 1 
ATOM   8019  N  N   . ILE C 3 112 ? 92.479  141.112 160.072 1.00 186.94 ? 112 ILE L N   1 
ATOM   8020  C  CA  . ILE C 3 112 ? 91.737  141.104 161.325 1.00 199.63 ? 112 ILE L CA  1 
ATOM   8021  C  C   . ILE C 3 112 ? 91.029  142.449 161.513 1.00 211.41 ? 112 ILE L C   1 
ATOM   8022  O  O   . ILE C 3 112 ? 91.584  143.506 161.201 1.00 264.39 ? 112 ILE L O   1 
ATOM   8023  C  CB  . ILE C 3 112 ? 92.671  140.755 162.501 1.00 221.93 ? 112 ILE L CB  1 
ATOM   8024  C  CG1 . ILE C 3 112 ? 93.375  139.401 162.308 1.00 236.50 ? 112 ILE L CG1 1 
ATOM   8025  C  CG2 . ILE C 3 112 ? 91.934  140.814 163.836 1.00 236.07 ? 112 ILE L CG2 1 
ATOM   8026  C  CD1 . ILE C 3 112 ? 92.488  138.177 162.143 1.00 170.90 ? 112 ILE L CD1 1 
ATOM   8027  N  N   . LYS C 3 113 ? 89.794  142.381 162.035 1.00 230.12 ? 113 LYS L N   1 
ATOM   8028  C  CA  . LYS C 3 113 ? 89.042  143.547 162.475 1.00 234.66 ? 113 LYS L CA  1 
ATOM   8029  C  C   . LYS C 3 113 ? 89.069  143.643 164.002 1.00 227.77 ? 113 LYS L C   1 
ATOM   8030  O  O   . LYS C 3 113 ? 88.823  142.640 164.691 1.00 241.60 ? 113 LYS L O   1 
ATOM   8031  C  CB  . LYS C 3 113 ? 87.600  143.467 161.968 1.00 234.23 ? 113 LYS L CB  1 
ATOM   8032  C  CG  . LYS C 3 113 ? 87.394  143.937 160.540 1.00 245.25 ? 113 LYS L CG  1 
ATOM   8033  C  CD  . LYS C 3 113 ? 86.061  143.501 159.970 1.00 233.36 ? 113 LYS L CD  1 
ATOM   8034  C  CE  . LYS C 3 113 ? 84.856  144.201 160.561 1.00 267.46 ? 113 LYS L CE  1 
ATOM   8035  N  NZ  . LYS C 3 113 ? 83.604  143.467 160.248 1.00 290.99 ? 113 LYS L NZ  1 
ATOM   8036  N  N   . ARG C 3 114 ? 89.351  144.864 164.492 1.00 206.90 ? 114 ARG L N   1 
ATOM   8037  C  CA  . ARG C 3 114 ? 89.391  145.172 165.909 1.00 236.71 ? 114 ARG L CA  1 
ATOM   8038  C  C   . ARG C 3 114 ? 88.728  146.528 166.169 1.00 277.18 ? 114 ARG L C   1 
ATOM   8039  O  O   . ARG C 3 114 ? 88.422  147.275 165.242 1.00 247.99 ? 114 ARG L O   1 
ATOM   8040  C  CB  . ARG C 3 114 ? 90.845  145.165 166.387 1.00 228.34 ? 114 ARG L CB  1 
ATOM   8041  C  CG  . ARG C 3 114 ? 91.762  146.159 165.677 1.00 225.14 ? 114 ARG L CG  1 
ATOM   8042  C  CD  . ARG C 3 114 ? 93.018  146.436 166.500 1.00 240.61 ? 114 ARG L CD  1 
ATOM   8043  N  NE  . ARG C 3 114 ? 92.755  147.315 167.641 1.00 264.45 ? 114 ARG L NE  1 
ATOM   8044  C  CZ  . ARG C 3 114 ? 93.354  147.278 168.837 1.00 302.43 ? 114 ARG L CZ  1 
ATOM   8045  N  NH1 . ARG C 3 114 ? 92.999  148.137 169.780 1.00 322.51 ? 114 ARG L NH1 1 
ATOM   8046  N  NH2 . ARG C 3 114 ? 94.303  146.394 169.101 1.00 305.23 ? 114 ARG L NH2 1 
ATOM   8047  N  N   . ALA C 3 115 ? 88.524  146.832 167.460 1.00 305.40 ? 115 ALA L N   1 
ATOM   8048  C  CA  . ALA C 3 115 ? 88.101  148.152 167.911 1.00 266.93 ? 115 ALA L CA  1 
ATOM   8049  C  C   . ALA C 3 115 ? 89.117  149.203 167.466 1.00 247.96 ? 115 ALA L C   1 
ATOM   8050  O  O   . ALA C 3 115 ? 90.310  149.051 167.708 1.00 272.78 ? 115 ALA L O   1 
ATOM   8051  C  CB  . ALA C 3 115 ? 87.943  148.167 169.415 1.00 273.18 ? 115 ALA L CB  1 
ATOM   8052  N  N   . ASP C 3 116 ? 88.630  150.269 166.814 1.00 285.20 ? 116 ASP L N   1 
ATOM   8053  C  CA  . ASP C 3 116 ? 89.473  151.322 166.256 1.00 304.25 ? 116 ASP L CA  1 
ATOM   8054  C  C   . ASP C 3 116 ? 90.301  151.992 167.364 1.00 273.48 ? 116 ASP L C   1 
ATOM   8055  O  O   . ASP C 3 116 ? 89.846  152.095 168.505 1.00 246.17 ? 116 ASP L O   1 
ATOM   8056  C  CB  . ASP C 3 116 ? 88.636  152.364 165.495 1.00 316.95 ? 116 ASP L CB  1 
ATOM   8057  C  CG  . ASP C 3 116 ? 87.727  151.858 164.377 1.00 325.21 ? 116 ASP L CG  1 
ATOM   8058  O  OD1 . ASP C 3 116 ? 87.531  150.621 164.250 1.00 293.14 ? 116 ASP L OD1 1 
ATOM   8059  O  OD2 . ASP C 3 116 ? 87.208  152.715 163.634 1.00 316.96 ? 116 ASP L OD2 1 
ATOM   8060  N  N   . ALA C 3 117 ? 91.521  152.447 167.021 1.00 271.68 ? 117 ALA L N   1 
ATOM   8061  C  CA  . ALA C 3 117 ? 92.423  153.081 167.975 1.00 258.46 ? 117 ALA L CA  1 
ATOM   8062  C  C   . ALA C 3 117 ? 93.318  154.117 167.289 1.00 246.58 ? 117 ALA L C   1 
ATOM   8063  O  O   . ALA C 3 117 ? 93.786  153.902 166.171 1.00 228.16 ? 117 ALA L O   1 
ATOM   8064  C  CB  . ALA C 3 117 ? 93.238  152.020 168.666 1.00 260.89 ? 117 ALA L CB  1 
ATOM   8065  N  N   . ALA C 3 118 ? 93.552  155.242 167.983 1.00 271.89 ? 118 ALA L N   1 
ATOM   8066  C  CA  . ALA C 3 118 ? 94.290  156.368 167.430 1.00 319.27 ? 118 ALA L CA  1 
ATOM   8067  C  C   . ALA C 3 118 ? 95.794  156.098 167.495 1.00 321.96 ? 118 ALA L C   1 
ATOM   8068  O  O   . ALA C 3 118 ? 96.254  155.419 168.422 1.00 239.38 ? 118 ALA L O   1 
ATOM   8069  C  CB  . ALA C 3 118 ? 93.949  157.635 168.179 1.00 371.30 ? 118 ALA L CB  1 
ATOM   8070  N  N   . PRO C 3 119 ? 96.603  156.632 166.538 1.00 300.47 ? 119 PRO L N   1 
ATOM   8071  C  CA  . PRO C 3 119 ? 98.050  156.398 166.536 1.00 286.89 ? 119 PRO L CA  1 
ATOM   8072  C  C   . PRO C 3 119 ? 98.755  157.119 167.685 1.00 254.66 ? 119 PRO L C   1 
ATOM   8073  O  O   . PRO C 3 119 ? 98.456  158.270 167.974 1.00 254.59 ? 119 PRO L O   1 
ATOM   8074  C  CB  . PRO C 3 119 ? 98.511  156.960 165.175 1.00 240.60 ? 119 PRO L CB  1 
ATOM   8075  C  CG  . PRO C 3 119 ? 97.494  158.031 164.857 1.00 228.01 ? 119 PRO L CG  1 
ATOM   8076  C  CD  . PRO C 3 119 ? 96.188  157.499 165.414 1.00 241.00 ? 119 PRO L CD  1 
ATOM   8077  N  N   . THR C 3 120 ? 99.697  156.429 168.333 1.00 267.20 ? 120 THR L N   1 
ATOM   8078  C  CA  . THR C 3 120 ? 100.780 157.098 169.033 1.00 284.15 ? 120 THR L CA  1 
ATOM   8079  C  C   . THR C 3 120 ? 101.647 157.801 167.987 1.00 268.47 ? 120 THR L C   1 
ATOM   8080  O  O   . THR C 3 120 ? 102.187 157.135 167.110 1.00 298.70 ? 120 THR L O   1 
ATOM   8081  C  CB  . THR C 3 120 ? 101.607 156.099 169.851 1.00 360.47 ? 120 THR L CB  1 
ATOM   8082  O  OG1 . THR C 3 120 ? 100.741 155.454 170.788 1.00 383.45 ? 120 THR L OG1 1 
ATOM   8083  C  CG2 . THR C 3 120 ? 102.768 156.744 170.579 1.00 397.80 ? 120 THR L CG2 1 
ATOM   8084  N  N   . VAL C 3 121 ? 101.776 159.131 168.069 1.00 254.36 ? 121 VAL L N   1 
ATOM   8085  C  CA  . VAL C 3 121 ? 102.551 159.892 167.092 1.00 280.67 ? 121 VAL L CA  1 
ATOM   8086  C  C   . VAL C 3 121 ? 103.818 160.416 167.768 1.00 279.50 ? 121 VAL L C   1 
ATOM   8087  O  O   . VAL C 3 121 ? 103.739 160.980 168.861 1.00 295.72 ? 121 VAL L O   1 
ATOM   8088  C  CB  . VAL C 3 121 ? 101.726 161.039 166.467 1.00 300.93 ? 121 VAL L CB  1 
ATOM   8089  C  CG1 . VAL C 3 121 ? 102.544 161.896 165.501 1.00 240.66 ? 121 VAL L CG1 1 
ATOM   8090  C  CG2 . VAL C 3 121 ? 100.467 160.515 165.782 1.00 298.18 ? 121 VAL L CG2 1 
ATOM   8091  N  N   . SER C 3 122 ? 104.965 160.229 167.085 1.00 272.32 ? 122 SER L N   1 
ATOM   8092  C  CA  . SER C 3 122 ? 106.277 160.670 167.541 1.00 297.66 ? 122 SER L CA  1 
ATOM   8093  C  C   . SER C 3 122 ? 107.096 161.197 166.363 1.00 252.88 ? 122 SER L C   1 
ATOM   8094  O  O   . SER C 3 122 ? 106.995 160.660 165.259 1.00 221.19 ? 122 SER L O   1 
ATOM   8095  C  CB  . SER C 3 122 ? 107.009 159.548 168.223 1.00 360.59 ? 122 SER L CB  1 
ATOM   8096  O  OG  . SER C 3 122 ? 106.302 159.097 169.369 1.00 380.36 ? 122 SER L OG  1 
ATOM   8097  N  N   . ILE C 3 123 ? 107.912 162.235 166.611 1.00 253.57 ? 123 ILE L N   1 
ATOM   8098  C  CA  . ILE C 3 123 ? 108.733 162.840 165.566 1.00 291.89 ? 123 ILE L CA  1 
ATOM   8099  C  C   . ILE C 3 123 ? 110.175 162.955 166.059 1.00 292.46 ? 123 ILE L C   1 
ATOM   8100  O  O   . ILE C 3 123 ? 110.410 163.311 167.216 1.00 257.43 ? 123 ILE L O   1 
ATOM   8101  C  CB  . ILE C 3 123 ? 108.171 164.198 165.082 1.00 265.15 ? 123 ILE L CB  1 
ATOM   8102  C  CG1 . ILE C 3 123 ? 108.987 164.722 163.892 1.00 226.04 ? 123 ILE L CG1 1 
ATOM   8103  C  CG2 . ILE C 3 123 ? 108.076 165.230 166.205 1.00 266.83 ? 123 ILE L CG2 1 
ATOM   8104  C  CD1 . ILE C 3 123 ? 108.331 165.826 163.144 1.00 210.11 ? 123 ILE L CD1 1 
ATOM   8105  N  N   . PHE C 3 124 ? 111.120 162.662 165.147 1.00 302.81 ? 124 PHE L N   1 
ATOM   8106  C  CA  . PHE C 3 124 ? 112.532 162.540 165.470 1.00 307.29 ? 124 PHE L CA  1 
ATOM   8107  C  C   . PHE C 3 124 ? 113.328 163.567 164.667 1.00 290.56 ? 124 PHE L C   1 
ATOM   8108  O  O   . PHE C 3 124 ? 113.376 163.489 163.443 1.00 238.60 ? 124 PHE L O   1 
ATOM   8109  C  CB  . PHE C 3 124 ? 113.000 161.107 165.216 1.00 294.44 ? 124 PHE L CB  1 
ATOM   8110  C  CG  . PHE C 3 124 ? 112.238 160.087 166.021 1.00 281.84 ? 124 PHE L CG  1 
ATOM   8111  C  CD1 . PHE C 3 124 ? 111.028 159.581 165.562 1.00 268.22 ? 124 PHE L CD1 1 
ATOM   8112  C  CD2 . PHE C 3 124 ? 112.721 159.646 167.250 1.00 324.40 ? 124 PHE L CD2 1 
ATOM   8113  C  CE1 . PHE C 3 124 ? 110.323 158.650 166.312 1.00 333.77 ? 124 PHE L CE1 1 
ATOM   8114  C  CE2 . PHE C 3 124 ? 112.015 158.714 167.998 1.00 343.20 ? 124 PHE L CE2 1 
ATOM   8115  C  CZ  . PHE C 3 124 ? 110.817 158.218 167.527 1.00 361.66 ? 124 PHE L CZ  1 
ATOM   8116  N  N   . PRO C 3 125 ? 113.980 164.562 165.317 1.00 309.88 ? 125 PRO L N   1 
ATOM   8117  C  CA  . PRO C 3 125 ? 114.911 165.453 164.619 1.00 309.53 ? 125 PRO L CA  1 
ATOM   8118  C  C   . PRO C 3 125 ? 116.065 164.704 163.946 1.00 286.16 ? 125 PRO L C   1 
ATOM   8119  O  O   . PRO C 3 125 ? 116.479 163.665 164.463 1.00 305.74 ? 125 PRO L O   1 
ATOM   8120  C  CB  . PRO C 3 125 ? 115.469 166.357 165.733 1.00 360.73 ? 125 PRO L CB  1 
ATOM   8121  C  CG  . PRO C 3 125 ? 114.433 166.291 166.838 1.00 349.28 ? 125 PRO L CG  1 
ATOM   8122  C  CD  . PRO C 3 125 ? 113.852 164.897 166.746 1.00 327.94 ? 125 PRO L CD  1 
ATOM   8123  N  N   . PRO C 3 126 ? 116.605 165.190 162.793 1.00 293.12 ? 126 PRO L N   1 
ATOM   8124  C  CA  . PRO C 3 126 ? 117.748 164.561 162.114 1.00 335.21 ? 126 PRO L CA  1 
ATOM   8125  C  C   . PRO C 3 126 ? 118.937 164.156 162.992 1.00 377.61 ? 126 PRO L C   1 
ATOM   8126  O  O   . PRO C 3 126 ? 119.318 164.879 163.915 1.00 433.19 ? 126 PRO L O   1 
ATOM   8127  C  CB  . PRO C 3 126 ? 118.203 165.638 161.113 1.00 306.82 ? 126 PRO L CB  1 
ATOM   8128  C  CG  . PRO C 3 126 ? 116.917 166.337 160.756 1.00 300.08 ? 126 PRO L CG  1 
ATOM   8129  C  CD  . PRO C 3 126 ? 116.128 166.370 162.052 1.00 275.62 ? 126 PRO L CD  1 
ATOM   8130  N  N   . SER C 3 127 ? 119.500 162.980 162.676 1.00 370.63 ? 127 SER L N   1 
ATOM   8131  C  CA  . SER C 3 127 ? 120.630 162.396 163.384 1.00 365.31 ? 127 SER L CA  1 
ATOM   8132  C  C   . SER C 3 127 ? 121.873 163.265 163.189 1.00 387.39 ? 127 SER L C   1 
ATOM   8133  O  O   . SER C 3 127 ? 122.183 163.613 162.054 1.00 393.17 ? 127 SER L O   1 
ATOM   8134  C  CB  . SER C 3 127 ? 120.888 160.979 162.904 1.00 346.62 ? 127 SER L CB  1 
ATOM   8135  O  OG  . SER C 3 127 ? 119.679 160.252 162.724 1.00 300.83 ? 127 SER L OG  1 
ATOM   8136  N  N   . SER C 3 128 ? 122.584 163.604 164.279 1.00 388.16 ? 128 SER L N   1 
ATOM   8137  C  CA  . SER C 3 128 ? 123.717 164.525 164.211 1.00 360.19 ? 128 SER L CA  1 
ATOM   8138  C  C   . SER C 3 128 ? 124.823 164.011 163.282 1.00 350.00 ? 128 SER L C   1 
ATOM   8139  O  O   . SER C 3 128 ? 125.541 164.827 162.705 1.00 290.44 ? 128 SER L O   1 
ATOM   8140  C  CB  . SER C 3 128 ? 124.261 164.851 165.590 1.00 355.25 ? 128 SER L CB  1 
ATOM   8141  O  OG  . SER C 3 128 ? 124.684 163.683 166.275 1.00 345.15 ? 128 SER L OG  1 
ATOM   8142  N  N   . GLU C 3 129 ? 124.944 162.677 163.127 1.00 387.64 ? 129 GLU L N   1 
ATOM   8143  C  CA  . GLU C 3 129 ? 125.881 162.061 162.190 1.00 394.69 ? 129 GLU L CA  1 
ATOM   8144  C  C   . GLU C 3 129 ? 125.457 162.297 160.736 1.00 333.06 ? 129 GLU L C   1 
ATOM   8145  O  O   . GLU C 3 129 ? 126.320 162.523 159.884 1.00 326.32 ? 129 GLU L O   1 
ATOM   8146  C  CB  . GLU C 3 129 ? 126.024 160.551 162.422 1.00 411.63 ? 129 GLU L CB  1 
ATOM   8147  C  CG  . GLU C 3 129 ? 126.347 160.163 163.859 1.00 431.98 ? 129 GLU L CG  1 
ATOM   8148  C  CD  . GLU C 3 129 ? 125.152 159.754 164.706 1.00 453.58 ? 129 GLU L CD  1 
ATOM   8149  O  OE1 . GLU C 3 129 ? 124.072 160.364 164.542 1.00 479.13 ? 129 GLU L OE1 1 
ATOM   8150  O  OE2 . GLU C 3 129 ? 125.303 158.829 165.529 1.00 483.59 ? 129 GLU L OE2 1 
ATOM   8151  N  N   . GLN C 3 130 ? 124.144 162.239 160.451 1.00 295.07 ? 130 GLN L N   1 
ATOM   8152  C  CA  . GLN C 3 130 ? 123.639 162.405 159.093 1.00 309.13 ? 130 GLN L CA  1 
ATOM   8153  C  C   . GLN C 3 130 ? 123.970 163.799 158.551 1.00 279.79 ? 130 GLN L C   1 
ATOM   8154  O  O   . GLN C 3 130 ? 124.222 163.936 157.360 1.00 256.20 ? 130 GLN L O   1 
ATOM   8155  C  CB  . GLN C 3 130 ? 122.130 162.158 159.007 1.00 354.35 ? 130 GLN L CB  1 
ATOM   8156  C  CG  . GLN C 3 130 ? 121.672 161.897 157.577 1.00 359.54 ? 130 GLN L CG  1 
ATOM   8157  C  CD  . GLN C 3 130 ? 120.179 161.792 157.392 1.00 375.20 ? 130 GLN L CD  1 
ATOM   8158  O  OE1 . GLN C 3 130 ? 119.385 162.015 158.307 1.00 375.37 ? 130 GLN L OE1 1 
ATOM   8159  N  NE2 . GLN C 3 130 ? 119.785 161.451 156.175 1.00 353.45 ? 130 GLN L NE2 1 
ATOM   8160  N  N   . LEU C 3 131 ? 123.993 164.819 159.423 1.00 322.93 ? 131 LEU L N   1 
ATOM   8161  C  CA  . LEU C 3 131 ? 124.285 166.201 159.050 1.00 373.22 ? 131 LEU L CA  1 
ATOM   8162  C  C   . LEU C 3 131 ? 125.683 166.362 158.429 1.00 400.55 ? 131 LEU L C   1 
ATOM   8163  O  O   . LEU C 3 131 ? 125.940 167.381 157.793 1.00 388.05 ? 131 LEU L O   1 
ATOM   8164  C  CB  . LEU C 3 131 ? 124.134 167.091 160.295 1.00 374.17 ? 131 LEU L CB  1 
ATOM   8165  C  CG  . LEU C 3 131 ? 122.759 167.108 160.977 1.00 333.47 ? 131 LEU L CG  1 
ATOM   8166  C  CD1 . LEU C 3 131 ? 122.780 167.989 162.217 1.00 333.91 ? 131 LEU L CD1 1 
ATOM   8167  C  CD2 . LEU C 3 131 ? 121.660 167.570 160.031 1.00 285.74 ? 131 LEU L CD2 1 
ATOM   8168  N  N   . THR C 3 132 ? 126.586 165.377 158.590 1.00 404.86 ? 132 THR L N   1 
ATOM   8169  C  CA  . THR C 3 132 ? 127.872 165.367 157.896 1.00 395.70 ? 132 THR L CA  1 
ATOM   8170  C  C   . THR C 3 132 ? 127.735 165.146 156.381 1.00 426.70 ? 132 THR L C   1 
ATOM   8171  O  O   . THR C 3 132 ? 128.642 165.529 155.641 1.00 447.38 ? 132 THR L O   1 
ATOM   8172  C  CB  . THR C 3 132 ? 128.828 164.310 158.478 1.00 345.35 ? 132 THR L CB  1 
ATOM   8173  O  OG1 . THR C 3 132 ? 128.316 163.003 158.212 1.00 344.19 ? 132 THR L OG1 1 
ATOM   8174  C  CG2 . THR C 3 132 ? 129.064 164.469 159.966 1.00 328.39 ? 132 THR L CG2 1 
ATOM   8175  N  N   . SER C 3 133 ? 126.620 164.544 155.920 1.00 433.18 ? 133 SER L N   1 
ATOM   8176  C  CA  . SER C 3 133 ? 126.461 164.032 154.561 1.00 438.07 ? 133 SER L CA  1 
ATOM   8177  C  C   . SER C 3 133 ? 126.108 165.096 153.516 1.00 438.98 ? 133 SER L C   1 
ATOM   8178  O  O   . SER C 3 133 ? 126.077 164.775 152.329 1.00 438.15 ? 133 SER L O   1 
ATOM   8179  C  CB  . SER C 3 133 ? 125.393 162.959 154.541 1.00 433.50 ? 133 SER L CB  1 
ATOM   8180  O  OG  . SER C 3 133 ? 124.099 163.521 154.752 1.00 412.30 ? 133 SER L OG  1 
ATOM   8181  N  N   . GLY C 3 134 ? 125.814 166.338 153.930 1.00 438.77 ? 134 GLY L N   1 
ATOM   8182  C  CA  . GLY C 3 134 ? 125.205 167.317 153.042 1.00 457.77 ? 134 GLY L CA  1 
ATOM   8183  C  C   . GLY C 3 134 ? 123.692 167.141 152.877 1.00 420.86 ? 134 GLY L C   1 
ATOM   8184  O  O   . GLY C 3 134 ? 123.068 167.970 152.214 1.00 447.97 ? 134 GLY L O   1 
ATOM   8185  N  N   . GLY C 3 135 ? 123.106 166.085 153.475 1.00 367.12 ? 135 GLY L N   1 
ATOM   8186  C  CA  . GLY C 3 135 ? 121.663 165.904 153.555 1.00 359.43 ? 135 GLY L CA  1 
ATOM   8187  C  C   . GLY C 3 135 ? 121.189 165.660 154.989 1.00 327.29 ? 135 GLY L C   1 
ATOM   8188  O  O   . GLY C 3 135 ? 121.999 165.527 155.905 1.00 267.75 ? 135 GLY L O   1 
ATOM   8189  N  N   . ALA C 3 136 ? 119.857 165.610 155.150 1.00 307.35 ? 136 ALA L N   1 
ATOM   8190  C  CA  . ALA C 3 136 ? 119.198 165.300 156.412 1.00 316.71 ? 136 ALA L CA  1 
ATOM   8191  C  C   . ALA C 3 136 ? 117.842 164.651 156.135 1.00 310.40 ? 136 ALA L C   1 
ATOM   8192  O  O   . ALA C 3 136 ? 117.190 165.001 155.151 1.00 299.09 ? 136 ALA L O   1 
ATOM   8193  C  CB  . ALA C 3 136 ? 119.035 166.556 157.222 1.00 310.84 ? 136 ALA L CB  1 
ATOM   8194  N  N   . SER C 3 137 ? 117.426 163.709 156.999 1.00 323.05 ? 137 SER L N   1 
ATOM   8195  C  CA  . SER C 3 137 ? 116.126 163.060 156.882 1.00 336.38 ? 137 SER L CA  1 
ATOM   8196  C  C   . SER C 3 137 ? 115.369 163.208 158.199 1.00 293.21 ? 137 SER L C   1 
ATOM   8197  O  O   . SER C 3 137 ? 115.854 162.762 159.236 1.00 227.66 ? 137 SER L O   1 
ATOM   8198  C  CB  . SER C 3 137 ? 116.234 161.601 156.492 1.00 417.20 ? 137 SER L CB  1 
ATOM   8199  O  OG  . SER C 3 137 ? 116.863 161.433 155.229 1.00 436.20 ? 137 SER L OG  1 
ATOM   8200  N  N   . VAL C 3 138 ? 114.177 163.823 158.130 1.00 279.05 ? 138 VAL L N   1 
ATOM   8201  C  CA  . VAL C 3 138 ? 113.267 163.961 159.257 1.00 274.70 ? 138 VAL L CA  1 
ATOM   8202  C  C   . VAL C 3 138 ? 112.265 162.809 159.197 1.00 285.17 ? 138 VAL L C   1 
ATOM   8203  O  O   . VAL C 3 138 ? 111.773 162.499 158.111 1.00 217.97 ? 138 VAL L O   1 
ATOM   8204  C  CB  . VAL C 3 138 ? 112.541 165.317 159.216 1.00 288.32 ? 138 VAL L CB  1 
ATOM   8205  C  CG1 . VAL C 3 138 ? 111.770 165.562 160.503 1.00 276.87 ? 138 VAL L CG1 1 
ATOM   8206  C  CG2 . VAL C 3 138 ? 113.483 166.481 158.925 1.00 315.04 ? 138 VAL L CG2 1 
ATOM   8207  N  N   . VAL C 3 139 ? 111.960 162.189 160.355 1.00 303.02 ? 139 VAL L N   1 
ATOM   8208  C  CA  . VAL C 3 139 ? 111.146 160.975 160.405 1.00 274.48 ? 139 VAL L CA  1 
ATOM   8209  C  C   . VAL C 3 139 ? 110.055 161.076 161.474 1.00 235.87 ? 139 VAL L C   1 
ATOM   8210  O  O   . VAL C 3 139 ? 110.312 161.466 162.614 1.00 217.75 ? 139 VAL L O   1 
ATOM   8211  C  CB  . VAL C 3 139 ? 112.021 159.726 160.628 1.00 296.44 ? 139 VAL L CB  1 
ATOM   8212  C  CG1 . VAL C 3 139 ? 111.194 158.483 160.930 1.00 300.92 ? 139 VAL L CG1 1 
ATOM   8213  C  CG2 . VAL C 3 139 ? 112.930 159.477 159.436 1.00 349.15 ? 139 VAL L CG2 1 
ATOM   8214  N  N   . CYS C 3 140 ? 108.836 160.686 161.069 1.00 256.75 ? 140 CYS L N   1 
ATOM   8215  C  CA  . CYS C 3 140 ? 107.652 160.678 161.910 1.00 306.52 ? 140 CYS L CA  1 
ATOM   8216  C  C   . CYS C 3 140 ? 107.094 159.255 161.960 1.00 274.05 ? 140 CYS L C   1 
ATOM   8217  O  O   . CYS C 3 140 ? 106.798 158.675 160.915 1.00 208.53 ? 140 CYS L O   1 
ATOM   8218  C  CB  . CYS C 3 140 ? 106.642 161.664 161.339 1.00 322.88 ? 140 CYS L CB  1 
ATOM   8219  S  SG  . CYS C 3 140 ? 105.151 161.919 162.334 1.00 303.87 ? 140 CYS L SG  1 
ATOM   8220  N  N   . PHE C 3 141 ? 106.957 158.709 163.176 1.00 256.98 ? 141 PHE L N   1 
ATOM   8221  C  CA  . PHE C 3 141 ? 106.408 157.384 163.389 1.00 242.63 ? 141 PHE L CA  1 
ATOM   8222  C  C   . PHE C 3 141 ? 105.007 157.461 163.976 1.00 252.76 ? 141 PHE L C   1 
ATOM   8223  O  O   . PHE C 3 141 ? 104.782 158.188 164.946 1.00 259.05 ? 141 PHE L O   1 
ATOM   8224  C  CB  . PHE C 3 141 ? 107.272 156.605 164.375 1.00 253.02 ? 141 PHE L CB  1 
ATOM   8225  C  CG  . PHE C 3 141 ? 108.594 156.083 163.872 1.00 232.75 ? 141 PHE L CG  1 
ATOM   8226  C  CD1 . PHE C 3 141 ? 108.922 156.013 162.518 1.00 247.47 ? 141 PHE L CD1 1 
ATOM   8227  C  CD2 . PHE C 3 141 ? 109.524 155.632 164.801 1.00 195.29 ? 141 PHE L CD2 1 
ATOM   8228  C  CE1 . PHE C 3 141 ? 110.157 155.505 162.125 1.00 287.25 ? 141 PHE L CE1 1 
ATOM   8229  C  CE2 . PHE C 3 141 ? 110.754 155.135 164.402 1.00 229.73 ? 141 PHE L CE2 1 
ATOM   8230  C  CZ  . PHE C 3 141 ? 111.068 155.063 163.065 1.00 275.89 ? 141 PHE L CZ  1 
ATOM   8231  N  N   . LEU C 3 142 ? 104.096 156.684 163.369 1.00 239.62 ? 142 LEU L N   1 
ATOM   8232  C  CA  . LEU C 3 142 ? 102.717 156.543 163.800 1.00 232.15 ? 142 LEU L CA  1 
ATOM   8233  C  C   . LEU C 3 142 ? 102.542 155.087 164.224 1.00 194.93 ? 142 LEU L C   1 
ATOM   8234  O  O   . LEU C 3 142 ? 102.596 154.208 163.375 1.00 188.22 ? 142 LEU L O   1 
ATOM   8235  C  CB  . LEU C 3 142 ? 101.796 156.930 162.632 1.00 224.42 ? 142 LEU L CB  1 
ATOM   8236  C  CG  . LEU C 3 142 ? 102.185 158.174 161.820 1.00 217.07 ? 142 LEU L CG  1 
ATOM   8237  C  CD1 . LEU C 3 142 ? 101.310 158.311 160.602 1.00 207.22 ? 142 LEU L CD1 1 
ATOM   8238  C  CD2 . LEU C 3 142 ? 102.092 159.449 162.648 1.00 268.23 ? 142 LEU L CD2 1 
ATOM   8239  N  N   . ASN C 3 143 ? 102.349 154.826 165.524 1.00 220.61 ? 143 ASN L N   1 
ATOM   8240  C  CA  . ASN C 3 143 ? 102.381 153.459 166.033 1.00 237.66 ? 143 ASN L CA  1 
ATOM   8241  C  C   . ASN C 3 143 ? 101.007 153.014 166.540 1.00 204.80 ? 143 ASN L C   1 
ATOM   8242  O  O   . ASN C 3 143 ? 100.303 153.778 167.198 1.00 292.45 ? 143 ASN L O   1 
ATOM   8243  C  CB  . ASN C 3 143 ? 103.428 153.284 167.135 1.00 261.01 ? 143 ASN L CB  1 
ATOM   8244  C  CG  . ASN C 3 143 ? 104.840 153.524 166.644 1.00 261.79 ? 143 ASN L CG  1 
ATOM   8245  O  OD1 . ASN C 3 143 ? 105.255 154.667 166.481 1.00 209.25 ? 143 ASN L OD1 1 
ATOM   8246  N  ND2 . ASN C 3 143 ? 105.586 152.455 166.408 1.00 283.00 ? 143 ASN L ND2 1 
ATOM   8247  N  N   . ASN C 3 144 ? 100.660 151.759 166.220 1.00 183.88 ? 144 ASN L N   1 
ATOM   8248  C  CA  . ASN C 3 144 ? 99.615  150.962 166.855 1.00 207.66 ? 144 ASN L CA  1 
ATOM   8249  C  C   . ASN C 3 144 ? 98.231  151.589 166.707 1.00 187.28 ? 144 ASN L C   1 
ATOM   8250  O  O   . ASN C 3 144 ? 97.645  152.043 167.692 1.00 285.71 ? 144 ASN L O   1 
ATOM   8251  C  CB  . ASN C 3 144 ? 99.900  150.674 168.336 1.00 244.34 ? 144 ASN L CB  1 
ATOM   8252  C  CG  . ASN C 3 144 ? 101.185 149.913 168.544 1.00 302.98 ? 144 ASN L CG  1 
ATOM   8253  O  OD1 . ASN C 3 144 ? 102.144 150.475 169.070 1.00 228.19 ? 144 ASN L OD1 1 
ATOM   8254  N  ND2 . ASN C 3 144 ? 101.208 148.655 168.127 1.00 366.62 ? 144 ASN L ND2 1 
ATOM   8255  N  N   . PHE C 3 145 ? 97.709  151.594 165.475 1.00 171.97 ? 145 PHE L N   1 
ATOM   8256  C  CA  . PHE C 3 145 ? 96.388  152.133 165.183 1.00 179.78 ? 145 PHE L CA  1 
ATOM   8257  C  C   . PHE C 3 145 ? 95.564  151.147 164.351 1.00 188.42 ? 145 PHE L C   1 
ATOM   8258  O  O   . PHE C 3 145 ? 96.084  150.156 163.838 1.00 231.79 ? 145 PHE L O   1 
ATOM   8259  C  CB  . PHE C 3 145 ? 96.546  153.492 164.499 1.00 196.09 ? 145 PHE L CB  1 
ATOM   8260  C  CG  . PHE C 3 145 ? 97.263  153.476 163.177 1.00 192.63 ? 145 PHE L CG  1 
ATOM   8261  C  CD1 . PHE C 3 145 ? 96.571  153.174 162.001 1.00 238.41 ? 145 PHE L CD1 1 
ATOM   8262  C  CD2 . PHE C 3 145 ? 98.618  153.767 163.106 1.00 170.32 ? 145 PHE L CD2 1 
ATOM   8263  C  CE1 . PHE C 3 145 ? 97.220  153.153 160.771 1.00 247.71 ? 145 PHE L CE1 1 
ATOM   8264  C  CE2 . PHE C 3 145 ? 99.256  153.749 161.870 1.00 238.48 ? 145 PHE L CE2 1 
ATOM   8265  C  CZ  . PHE C 3 145 ? 98.565  153.440 160.704 1.00 230.26 ? 145 PHE L CZ  1 
ATOM   8266  N  N   . TYR C 3 146 ? 94.264  151.432 164.233 1.00 185.44 ? 146 TYR L N   1 
ATOM   8267  C  CA  . TYR C 3 146 ? 93.371  150.651 163.390 1.00 206.44 ? 146 TYR L CA  1 
ATOM   8268  C  C   . TYR C 3 146 ? 92.194  151.534 163.004 1.00 191.01 ? 146 TYR L C   1 
ATOM   8269  O  O   . TYR C 3 146 ? 91.733  152.273 163.865 1.00 236.60 ? 146 TYR L O   1 
ATOM   8270  C  CB  . TYR C 3 146 ? 92.832  149.387 164.081 1.00 195.46 ? 146 TYR L CB  1 
ATOM   8271  C  CG  . TYR C 3 146 ? 92.080  148.498 163.100 1.00 194.00 ? 146 TYR L CG  1 
ATOM   8272  C  CD1 . TYR C 3 146 ? 92.743  147.551 162.325 1.00 253.96 ? 146 TYR L CD1 1 
ATOM   8273  C  CD2 . TYR C 3 146 ? 90.712  148.635 162.912 1.00 227.87 ? 146 TYR L CD2 1 
ATOM   8274  C  CE1 . TYR C 3 146 ? 92.063  146.752 161.415 1.00 319.04 ? 146 TYR L CE1 1 
ATOM   8275  C  CE2 . TYR C 3 146 ? 90.020  147.847 162.003 1.00 275.39 ? 146 TYR L CE2 1 
ATOM   8276  C  CZ  . TYR C 3 146 ? 90.695  146.899 161.249 1.00 304.82 ? 146 TYR L CZ  1 
ATOM   8277  O  OH  . TYR C 3 146 ? 90.022  146.107 160.357 1.00 339.58 ? 146 TYR L OH  1 
ATOM   8278  N  N   . PRO C 3 147 ? 91.628  151.494 161.771 1.00 210.44 ? 147 PRO L N   1 
ATOM   8279  C  CA  . PRO C 3 147 ? 92.100  150.699 160.631 1.00 212.24 ? 147 PRO L CA  1 
ATOM   8280  C  C   . PRO C 3 147 ? 93.250  151.364 159.888 1.00 197.18 ? 147 PRO L C   1 
ATOM   8281  O  O   . PRO C 3 147 ? 93.720  152.431 160.285 1.00 175.38 ? 147 PRO L O   1 
ATOM   8282  C  CB  . PRO C 3 147 ? 90.838  150.624 159.755 1.00 271.08 ? 147 PRO L CB  1 
ATOM   8283  C  CG  . PRO C 3 147 ? 90.195  151.984 159.952 1.00 283.60 ? 147 PRO L CG  1 
ATOM   8284  C  CD  . PRO C 3 147 ? 90.417  152.254 161.424 1.00 269.95 ? 147 PRO L CD  1 
ATOM   8285  N  N   . LYS C 3 148 ? 93.675  150.684 158.808 1.00 220.80 ? 148 LYS L N   1 
ATOM   8286  C  CA  . LYS C 3 148 ? 94.837  151.021 157.995 1.00 251.95 ? 148 LYS L CA  1 
ATOM   8287  C  C   . LYS C 3 148 ? 94.794  152.442 157.405 1.00 254.59 ? 148 LYS L C   1 
ATOM   8288  O  O   . LYS C 3 148 ? 95.848  153.054 157.268 1.00 283.63 ? 148 LYS L O   1 
ATOM   8289  C  CB  . LYS C 3 148 ? 94.965  149.985 156.869 1.00 224.85 ? 148 LYS L CB  1 
ATOM   8290  C  CG  . LYS C 3 148 ? 96.207  150.129 156.005 1.00 254.87 ? 148 LYS L CG  1 
ATOM   8291  C  CD  . LYS C 3 148 ? 96.367  149.085 154.926 1.00 293.03 ? 148 LYS L CD  1 
ATOM   8292  C  CE  . LYS C 3 148 ? 97.507  149.429 153.987 1.00 321.54 ? 148 LYS L CE  1 
ATOM   8293  N  NZ  . LYS C 3 148 ? 97.888  148.293 153.115 1.00 338.71 ? 148 LYS L NZ  1 
ATOM   8294  N  N   . ASP C 3 149 ? 93.617  152.969 157.036 1.00 263.03 ? 149 ASP L N   1 
ATOM   8295  C  CA  . ASP C 3 149 ? 93.522  154.264 156.363 1.00 287.89 ? 149 ASP L CA  1 
ATOM   8296  C  C   . ASP C 3 149 ? 93.980  155.406 157.276 1.00 257.60 ? 149 ASP L C   1 
ATOM   8297  O  O   . ASP C 3 149 ? 93.469  155.565 158.385 1.00 209.91 ? 149 ASP L O   1 
ATOM   8298  C  CB  . ASP C 3 149 ? 92.101  154.561 155.863 1.00 376.40 ? 149 ASP L CB  1 
ATOM   8299  C  CG  . ASP C 3 149 ? 91.708  153.921 154.540 1.00 410.10 ? 149 ASP L CG  1 
ATOM   8300  O  OD1 . ASP C 3 149 ? 92.545  153.215 153.934 1.00 421.10 ? 149 ASP L OD1 1 
ATOM   8301  O  OD2 . ASP C 3 149 ? 90.553  154.135 154.122 1.00 436.64 ? 149 ASP L OD2 1 
ATOM   8302  N  N   . ILE C 3 150 ? 94.943  156.197 156.771 1.00 262.33 ? 150 ILE L N   1 
ATOM   8303  C  CA  . ILE C 3 150 ? 95.548  157.320 157.480 1.00 245.42 ? 150 ILE L CA  1 
ATOM   8304  C  C   . ILE C 3 150 ? 96.137  158.289 156.449 1.00 253.07 ? 150 ILE L C   1 
ATOM   8305  O  O   . ILE C 3 150 ? 96.405  157.885 155.316 1.00 197.25 ? 150 ILE L O   1 
ATOM   8306  C  CB  . ILE C 3 150 ? 96.597  156.785 158.487 1.00 223.27 ? 150 ILE L CB  1 
ATOM   8307  C  CG1 . ILE C 3 150 ? 97.030  157.830 159.507 1.00 207.03 ? 150 ILE L CG1 1 
ATOM   8308  C  CG2 . ILE C 3 150 ? 97.821  156.187 157.810 1.00 260.32 ? 150 ILE L CG2 1 
ATOM   8309  C  CD1 . ILE C 3 150 ? 97.815  157.232 160.656 1.00 200.66 ? 150 ILE L CD1 1 
ATOM   8310  N  N   . ASN C 3 151 ? 96.332  159.564 156.827 1.00 290.69 ? 151 ASN L N   1 
ATOM   8311  C  CA  . ASN C 3 151 ? 97.149  160.467 156.023 1.00 330.80 ? 151 ASN L CA  1 
ATOM   8312  C  C   . ASN C 3 151 ? 97.962  161.395 156.931 1.00 302.86 ? 151 ASN L C   1 
ATOM   8313  O  O   . ASN C 3 151 ? 97.633  161.612 158.104 1.00 219.40 ? 151 ASN L O   1 
ATOM   8314  C  CB  . ASN C 3 151 ? 96.321  161.200 154.945 1.00 374.53 ? 151 ASN L CB  1 
ATOM   8315  C  CG  . ASN C 3 151 ? 95.260  162.172 155.436 1.00 359.47 ? 151 ASN L CG  1 
ATOM   8316  O  OD1 . ASN C 3 151 ? 95.517  162.985 156.319 1.00 395.50 ? 151 ASN L OD1 1 
ATOM   8317  N  ND2 . ASN C 3 151 ? 94.064  162.114 154.864 1.00 308.62 ? 151 ASN L ND2 1 
ATOM   8318  N  N   . VAL C 3 152 ? 99.040  161.946 156.346 1.00 302.39 ? 152 VAL L N   1 
ATOM   8319  C  CA  . VAL C 3 152 ? 100.012 162.765 157.050 1.00 292.12 ? 152 VAL L CA  1 
ATOM   8320  C  C   . VAL C 3 152 ? 100.215 164.081 156.305 1.00 318.04 ? 152 VAL L C   1 
ATOM   8321  O  O   . VAL C 3 152 ? 100.372 164.083 155.084 1.00 330.72 ? 152 VAL L O   1 
ATOM   8322  C  CB  . VAL C 3 152 ? 101.350 162.022 157.180 1.00 300.28 ? 152 VAL L CB  1 
ATOM   8323  C  CG1 . VAL C 3 152 ? 102.348 162.810 158.021 1.00 327.05 ? 152 VAL L CG1 1 
ATOM   8324  C  CG2 . VAL C 3 152 ? 101.142 160.622 157.734 1.00 299.94 ? 152 VAL L CG2 1 
ATOM   8325  N  N   . LYS C 3 153 ? 100.222 165.185 157.070 1.00 315.94 ? 153 LYS L N   1 
ATOM   8326  C  CA  . LYS C 3 153 ? 100.655 166.495 156.608 1.00 327.64 ? 153 LYS L CA  1 
ATOM   8327  C  C   . LYS C 3 153 ? 102.018 166.823 157.222 1.00 283.65 ? 153 LYS L C   1 
ATOM   8328  O  O   . LYS C 3 153 ? 102.197 166.733 158.436 1.00 240.55 ? 153 LYS L O   1 
ATOM   8329  C  CB  . LYS C 3 153 ? 99.619  167.562 156.983 1.00 370.80 ? 153 LYS L CB  1 
ATOM   8330  C  CG  . LYS C 3 153 ? 98.585  167.887 155.914 1.00 414.93 ? 153 LYS L CG  1 
ATOM   8331  C  CD  . LYS C 3 153 ? 97.698  166.732 155.511 1.00 441.92 ? 153 LYS L CD  1 
ATOM   8332  C  CE  . LYS C 3 153 ? 96.669  167.119 154.468 1.00 475.74 ? 153 LYS L CE  1 
ATOM   8333  N  NZ  . LYS C 3 153 ? 97.289  167.481 153.170 1.00 505.75 ? 153 LYS L NZ  1 
ATOM   8334  N  N   . TRP C 3 154 ? 102.978 167.203 156.372 1.00 275.89 ? 154 TRP L N   1 
ATOM   8335  C  CA  . TRP C 3 154 ? 104.222 167.796 156.832 1.00 316.53 ? 154 TRP L CA  1 
ATOM   8336  C  C   . TRP C 3 154 ? 104.138 169.311 156.683 1.00 304.25 ? 154 TRP L C   1 
ATOM   8337  O  O   . TRP C 3 154 ? 103.792 169.801 155.606 1.00 297.58 ? 154 TRP L O   1 
ATOM   8338  C  CB  . TRP C 3 154 ? 105.410 167.218 156.054 1.00 365.12 ? 154 TRP L CB  1 
ATOM   8339  C  CG  . TRP C 3 154 ? 105.826 165.857 156.542 1.00 324.13 ? 154 TRP L CG  1 
ATOM   8340  C  CD1 . TRP C 3 154 ? 105.384 164.663 156.062 1.00 307.78 ? 154 TRP L CD1 1 
ATOM   8341  C  CD2 . TRP C 3 154 ? 106.766 165.554 157.598 1.00 293.25 ? 154 TRP L CD2 1 
ATOM   8342  N  NE1 . TRP C 3 154 ? 105.978 163.636 156.743 1.00 330.23 ? 154 TRP L NE1 1 
ATOM   8343  C  CE2 . TRP C 3 154 ? 106.829 164.145 157.688 1.00 323.37 ? 154 TRP L CE2 1 
ATOM   8344  C  CE3 . TRP C 3 154 ? 107.554 166.322 158.468 1.00 262.05 ? 154 TRP L CE3 1 
ATOM   8345  C  CZ2 . TRP C 3 154 ? 107.647 163.493 158.612 1.00 343.87 ? 154 TRP L CZ2 1 
ATOM   8346  C  CZ3 . TRP C 3 154 ? 108.362 165.675 159.380 1.00 276.50 ? 154 TRP L CZ3 1 
ATOM   8347  C  CH2 . TRP C 3 154 ? 108.408 164.278 159.450 1.00 318.31 ? 154 TRP L CH2 1 
ATOM   8348  N  N   . LYS C 3 155 ? 104.455 170.034 157.770 1.00 293.07 ? 155 LYS L N   1 
ATOM   8349  C  CA  . LYS C 3 155 ? 104.545 171.487 157.761 1.00 303.26 ? 155 LYS L CA  1 
ATOM   8350  C  C   . LYS C 3 155 ? 105.956 171.913 158.175 1.00 319.58 ? 155 LYS L C   1 
ATOM   8351  O  O   . LYS C 3 155 ? 106.561 171.326 159.069 1.00 246.27 ? 155 LYS L O   1 
ATOM   8352  C  CB  . LYS C 3 155 ? 103.473 172.101 158.668 1.00 339.09 ? 155 LYS L CB  1 
ATOM   8353  C  CG  . LYS C 3 155 ? 102.219 172.607 157.960 1.00 340.00 ? 155 LYS L CG  1 
ATOM   8354  C  CD  . LYS C 3 155 ? 101.331 171.526 157.377 1.00 328.70 ? 155 LYS L CD  1 
ATOM   8355  C  CE  . LYS C 3 155 ? 100.027 172.046 156.809 1.00 357.16 ? 155 LYS L CE  1 
ATOM   8356  N  NZ  . LYS C 3 155 ? 99.050  172.394 157.869 1.00 351.29 ? 155 LYS L NZ  1 
ATOM   8357  N  N   . ILE C 3 156 ? 106.460 172.956 157.506 1.00 368.78 ? 156 ILE L N   1 
ATOM   8358  C  CA  . ILE C 3 156 ? 107.826 173.439 157.646 1.00 390.95 ? 156 ILE L CA  1 
ATOM   8359  C  C   . ILE C 3 156 ? 107.751 174.972 157.685 1.00 438.82 ? 156 ILE L C   1 
ATOM   8360  O  O   . ILE C 3 156 ? 107.408 175.610 156.686 1.00 503.87 ? 156 ILE L O   1 
ATOM   8361  C  CB  . ILE C 3 156 ? 108.722 172.839 156.528 1.00 372.07 ? 156 ILE L CB  1 
ATOM   8362  C  CG1 . ILE C 3 156 ? 110.115 173.475 156.494 1.00 412.47 ? 156 ILE L CG1 1 
ATOM   8363  C  CG2 . ILE C 3 156 ? 108.073 172.892 155.143 1.00 323.95 ? 156 ILE L CG2 1 
ATOM   8364  C  CD1 . ILE C 3 156 ? 111.099 172.774 155.580 1.00 416.51 ? 156 ILE L CD1 1 
ATOM   8365  N  N   . ASP C 3 157 ? 108.041 175.555 158.864 1.00 404.69 ? 157 ASP L N   1 
ATOM   8366  C  CA  . ASP C 3 157 ? 107.742 176.949 159.193 1.00 396.14 ? 157 ASP L CA  1 
ATOM   8367  C  C   . ASP C 3 157 ? 106.305 177.329 158.793 1.00 422.89 ? 157 ASP L C   1 
ATOM   8368  O  O   . ASP C 3 157 ? 106.061 178.460 158.367 1.00 464.81 ? 157 ASP L O   1 
ATOM   8369  C  CB  . ASP C 3 157 ? 108.819 177.866 158.587 1.00 372.15 ? 157 ASP L CB  1 
ATOM   8370  C  CG  . ASP C 3 157 ? 110.210 177.739 159.197 1.00 331.84 ? 157 ASP L CG  1 
ATOM   8371  O  OD1 . ASP C 3 157 ? 110.357 177.059 160.228 1.00 291.56 ? 157 ASP L OD1 1 
ATOM   8372  O  OD2 . ASP C 3 157 ? 111.151 178.330 158.640 1.00 321.78 ? 157 ASP L OD2 1 
ATOM   8373  N  N   . GLY C 3 158 ? 105.352 176.387 158.931 1.00 389.44 ? 158 GLY L N   1 
ATOM   8374  C  CA  . GLY C 3 158 ? 103.962 176.606 158.545 1.00 373.09 ? 158 GLY L CA  1 
ATOM   8375  C  C   . GLY C 3 158 ? 103.618 176.289 157.084 1.00 370.71 ? 158 GLY L C   1 
ATOM   8376  O  O   . GLY C 3 158 ? 102.442 176.085 156.786 1.00 288.28 ? 158 GLY L O   1 
ATOM   8377  N  N   . SER C 3 159 ? 104.609 176.250 156.175 1.00 447.89 ? 159 SER L N   1 
ATOM   8378  C  CA  . SER C 3 159 ? 104.383 175.892 154.778 1.00 494.86 ? 159 SER L CA  1 
ATOM   8379  C  C   . SER C 3 159 ? 104.123 174.388 154.643 1.00 473.19 ? 159 SER L C   1 
ATOM   8380  O  O   . SER C 3 159 ? 104.825 173.596 155.259 1.00 468.83 ? 159 SER L O   1 
ATOM   8381  C  CB  . SER C 3 159 ? 105.556 176.326 153.926 1.00 512.70 ? 159 SER L CB  1 
ATOM   8382  O  OG  . SER C 3 159 ? 105.313 176.075 152.549 1.00 502.83 ? 159 SER L OG  1 
ATOM   8383  N  N   . GLU C 3 160 ? 103.124 173.996 153.832 1.00 416.00 ? 160 GLU L N   1 
ATOM   8384  C  CA  . GLU C 3 160 ? 102.787 172.592 153.613 1.00 370.43 ? 160 GLU L CA  1 
ATOM   8385  C  C   . GLU C 3 160 ? 103.754 171.957 152.604 1.00 362.85 ? 160 GLU L C   1 
ATOM   8386  O  O   . GLU C 3 160 ? 103.989 172.518 151.532 1.00 349.20 ? 160 GLU L O   1 
ATOM   8387  C  CB  . GLU C 3 160 ? 101.339 172.468 153.126 1.00 397.54 ? 160 GLU L CB  1 
ATOM   8388  C  CG  . GLU C 3 160 ? 100.842 171.031 153.038 1.00 459.95 ? 160 GLU L CG  1 
ATOM   8389  C  CD  . GLU C 3 160 ? 99.373  170.861 152.679 1.00 489.54 ? 160 GLU L CD  1 
ATOM   8390  O  OE1 . GLU C 3 160 ? 98.769  171.823 152.154 1.00 451.41 ? 160 GLU L OE1 1 
ATOM   8391  O  OE2 . GLU C 3 160 ? 98.830  169.760 152.932 1.00 551.87 ? 160 GLU L OE2 1 
ATOM   8392  N  N   . ARG C 3 161 ? 104.294 170.769 152.947 1.00 374.02 ? 161 ARG L N   1 
ATOM   8393  C  CA  . ARG C 3 161 ? 105.289 170.072 152.138 1.00 354.27 ? 161 ARG L CA  1 
ATOM   8394  C  C   . ARG C 3 161 ? 104.686 168.815 151.495 1.00 325.27 ? 161 ARG L C   1 
ATOM   8395  O  O   . ARG C 3 161 ? 104.093 167.973 152.178 1.00 218.48 ? 161 ARG L O   1 
ATOM   8396  C  CB  . ARG C 3 161 ? 106.495 169.719 153.013 1.00 356.59 ? 161 ARG L CB  1 
ATOM   8397  C  CG  . ARG C 3 161 ? 107.664 169.072 152.282 1.00 359.57 ? 161 ARG L CG  1 
ATOM   8398  C  CD  . ARG C 3 161 ? 108.259 169.893 151.148 1.00 341.44 ? 161 ARG L CD  1 
ATOM   8399  N  NE  . ARG C 3 161 ? 109.452 169.226 150.621 1.00 370.60 ? 161 ARG L NE  1 
ATOM   8400  C  CZ  . ARG C 3 161 ? 110.659 169.773 150.433 1.00 438.72 ? 161 ARG L CZ  1 
ATOM   8401  N  NH1 . ARG C 3 161 ? 111.670 169.011 150.046 1.00 463.45 ? 161 ARG L NH1 1 
ATOM   8402  N  NH2 . ARG C 3 161 ? 110.875 171.064 150.633 1.00 450.03 ? 161 ARG L NH2 1 
ATOM   8403  N  N   . GLN C 3 162 ? 104.858 168.700 150.166 1.00 343.03 ? 162 GLN L N   1 
ATOM   8404  C  CA  . GLN C 3 162 ? 104.323 167.590 149.375 1.00 390.50 ? 162 GLN L CA  1 
ATOM   8405  C  C   . GLN C 3 162 ? 105.344 166.997 148.384 1.00 416.03 ? 162 GLN L C   1 
ATOM   8406  O  O   . GLN C 3 162 ? 105.076 165.926 147.830 1.00 398.79 ? 162 GLN L O   1 
ATOM   8407  C  CB  . GLN C 3 162 ? 103.029 168.045 148.685 1.00 391.24 ? 162 GLN L CB  1 
ATOM   8408  C  CG  . GLN C 3 162 ? 103.197 169.199 147.695 1.00 437.57 ? 162 GLN L CG  1 
ATOM   8409  C  CD  . GLN C 3 162 ? 101.943 170.019 147.467 1.00 448.17 ? 162 GLN L CD  1 
ATOM   8410  O  OE1 . GLN C 3 162 ? 100.880 169.755 148.028 1.00 416.42 ? 162 GLN L OE1 1 
ATOM   8411  N  NE2 . GLN C 3 162 ? 102.062 171.040 146.632 1.00 463.09 ? 162 GLN L NE2 1 
ATOM   8412  N  N   . ASN C 3 163 ? 106.496 167.659 148.154 1.00 410.50 ? 163 ASN L N   1 
ATOM   8413  C  CA  . ASN C 3 163 ? 107.651 167.070 147.482 1.00 425.96 ? 163 ASN L CA  1 
ATOM   8414  C  C   . ASN C 3 163 ? 108.506 166.267 148.468 1.00 424.25 ? 163 ASN L C   1 
ATOM   8415  O  O   . ASN C 3 163 ? 108.670 166.683 149.614 1.00 428.41 ? 163 ASN L O   1 
ATOM   8416  C  CB  . ASN C 3 163 ? 108.535 168.148 146.844 1.00 464.96 ? 163 ASN L CB  1 
ATOM   8417  C  CG  . ASN C 3 163 ? 107.847 168.994 145.792 1.00 495.93 ? 163 ASN L CG  1 
ATOM   8418  O  OD1 . ASN C 3 163 ? 106.877 168.569 145.167 1.00 548.30 ? 163 ASN L OD1 1 
ATOM   8419  N  ND2 . ASN C 3 163 ? 108.352 170.199 145.577 1.00 478.75 ? 163 ASN L ND2 1 
ATOM   8420  N  N   . GLY C 3 164 ? 109.059 165.124 148.018 1.00 394.37 ? 164 GLY L N   1 
ATOM   8421  C  CA  . GLY C 3 164 ? 110.063 164.372 148.766 1.00 372.21 ? 164 GLY L CA  1 
ATOM   8422  C  C   . GLY C 3 164 ? 109.569 163.783 150.094 1.00 346.73 ? 164 GLY L C   1 
ATOM   8423  O  O   . GLY C 3 164 ? 110.366 163.647 151.029 1.00 196.73 ? 164 GLY L O   1 
ATOM   8424  N  N   . VAL C 3 165 ? 108.264 163.442 150.152 1.00 384.38 ? 165 VAL L N   1 
ATOM   8425  C  CA  . VAL C 3 165 ? 107.634 162.765 151.281 1.00 345.47 ? 165 VAL L CA  1 
ATOM   8426  C  C   . VAL C 3 165 ? 107.337 161.315 150.883 1.00 327.84 ? 165 VAL L C   1 
ATOM   8427  O  O   . VAL C 3 165 ? 106.779 161.061 149.814 1.00 274.98 ? 165 VAL L O   1 
ATOM   8428  C  CB  . VAL C 3 165 ? 106.362 163.505 151.751 1.00 347.01 ? 165 VAL L CB  1 
ATOM   8429  C  CG1 . VAL C 3 165 ? 105.459 162.663 152.652 1.00 309.89 ? 165 VAL L CG1 1 
ATOM   8430  C  CG2 . VAL C 3 165 ? 106.734 164.806 152.444 1.00 354.63 ? 165 VAL L CG2 1 
ATOM   8431  N  N   . LEU C 3 166 ? 107.697 160.387 151.783 1.00 310.47 ? 166 LEU L N   1 
ATOM   8432  C  CA  . LEU C 3 166 ? 107.564 158.955 151.577 1.00 289.19 ? 166 LEU L CA  1 
ATOM   8433  C  C   . LEU C 3 166 ? 106.902 158.325 152.799 1.00 288.69 ? 166 LEU L C   1 
ATOM   8434  O  O   . LEU C 3 166 ? 107.057 158.827 153.910 1.00 214.85 ? 166 LEU L O   1 
ATOM   8435  C  CB  . LEU C 3 166 ? 108.959 158.366 151.368 1.00 236.11 ? 166 LEU L CB  1 
ATOM   8436  C  CG  . LEU C 3 166 ? 109.718 158.886 150.157 1.00 255.55 ? 166 LEU L CG  1 
ATOM   8437  C  CD1 . LEU C 3 166 ? 111.183 158.455 150.213 1.00 278.17 ? 166 LEU L CD1 1 
ATOM   8438  C  CD2 . LEU C 3 166 ? 109.048 158.395 148.884 1.00 261.85 ? 166 LEU L CD2 1 
ATOM   8439  N  N   . ASN C 3 167 ? 106.177 157.223 152.559 1.00 283.15 ? 167 ASN L N   1 
ATOM   8440  C  CA  . ASN C 3 167 ? 105.439 156.512 153.589 1.00 240.88 ? 167 ASN L CA  1 
ATOM   8441  C  C   . ASN C 3 167 ? 105.663 155.009 153.463 1.00 269.34 ? 167 ASN L C   1 
ATOM   8442  O  O   . ASN C 3 167 ? 105.858 154.493 152.357 1.00 283.45 ? 167 ASN L O   1 
ATOM   8443  C  CB  . ASN C 3 167 ? 103.942 156.796 153.493 1.00 235.38 ? 167 ASN L CB  1 
ATOM   8444  C  CG  . ASN C 3 167 ? 103.597 158.260 153.682 1.00 257.86 ? 167 ASN L CG  1 
ATOM   8445  O  OD1 . ASN C 3 167 ? 104.158 158.937 154.540 1.00 253.96 ? 167 ASN L OD1 1 
ATOM   8446  N  ND2 . ASN C 3 167 ? 102.670 158.767 152.888 1.00 302.23 ? 167 ASN L ND2 1 
ATOM   8447  N  N   . SER C 3 168 ? 105.624 154.309 154.607 1.00 253.55 ? 168 SER L N   1 
ATOM   8448  C  CA  . SER C 3 168 ? 105.580 152.854 154.600 1.00 239.37 ? 168 SER L CA  1 
ATOM   8449  C  C   . SER C 3 168 ? 104.774 152.338 155.793 1.00 200.02 ? 168 SER L C   1 
ATOM   8450  O  O   . SER C 3 168 ? 105.060 152.687 156.937 1.00 169.35 ? 168 SER L O   1 
ATOM   8451  C  CB  . SER C 3 168 ? 106.968 152.277 154.584 1.00 289.57 ? 168 SER L CB  1 
ATOM   8452  O  OG  . SER C 3 168 ? 106.915 150.859 154.575 1.00 310.35 ? 168 SER L OG  1 
ATOM   8453  N  N   . TRP C 3 169 ? 103.772 151.498 155.503 1.00 203.46 ? 169 TRP L N   1 
ATOM   8454  C  CA  . TRP C 3 169 ? 102.974 150.822 156.513 1.00 231.42 ? 169 TRP L CA  1 
ATOM   8455  C  C   . TRP C 3 169 ? 103.604 149.488 156.862 1.00 215.51 ? 169 TRP L C   1 
ATOM   8456  O  O   . TRP C 3 169 ? 104.096 148.809 155.962 1.00 255.28 ? 169 TRP L O   1 
ATOM   8457  C  CB  . TRP C 3 169 ? 101.575 150.495 155.983 1.00 274.82 ? 169 TRP L CB  1 
ATOM   8458  C  CG  . TRP C 3 169 ? 100.599 151.633 155.896 1.00 236.45 ? 169 TRP L CG  1 
ATOM   8459  C  CD1 . TRP C 3 169 ? 99.544  151.811 156.738 1.00 185.57 ? 169 TRP L CD1 1 
ATOM   8460  C  CD2 . TRP C 3 169 ? 100.568 152.715 154.938 1.00 233.44 ? 169 TRP L CD2 1 
ATOM   8461  N  NE1 . TRP C 3 169 ? 98.851  152.926 156.370 1.00 212.84 ? 169 TRP L NE1 1 
ATOM   8462  C  CE2 . TRP C 3 169 ? 99.449  153.505 155.277 1.00 251.21 ? 169 TRP L CE2 1 
ATOM   8463  C  CE3 . TRP C 3 169 ? 101.358 153.102 153.845 1.00 259.99 ? 169 TRP L CE3 1 
ATOM   8464  C  CZ2 . TRP C 3 169 ? 99.108  154.654 154.560 1.00 328.01 ? 169 TRP L CZ2 1 
ATOM   8465  C  CZ3 . TRP C 3 169 ? 101.026 154.241 153.141 1.00 321.02 ? 169 TRP L CZ3 1 
ATOM   8466  C  CH2 . TRP C 3 169 ? 99.909  155.004 153.494 1.00 345.58 ? 169 TRP L CH2 1 
ATOM   8467  N  N   . THR C 3 170 ? 103.544 149.089 158.137 1.00 162.99 ? 170 THR L N   1 
ATOM   8468  C  CA  . THR C 3 170 ? 103.767 147.684 158.436 1.00 199.36 ? 170 THR L CA  1 
ATOM   8469  C  C   . THR C 3 170 ? 102.562 146.851 157.998 1.00 205.22 ? 170 THR L C   1 
ATOM   8470  O  O   . THR C 3 170 ? 101.455 147.350 157.905 1.00 200.32 ? 170 THR L O   1 
ATOM   8471  C  CB  . THR C 3 170 ? 104.056 147.405 159.916 1.00 223.32 ? 170 THR L CB  1 
ATOM   8472  O  OG1 . THR C 3 170 ? 102.840 147.549 160.659 1.00 191.56 ? 170 THR L OG1 1 
ATOM   8473  C  CG2 . THR C 3 170 ? 105.183 148.270 160.447 1.00 219.56 ? 170 THR L CG2 1 
ATOM   8474  N  N   . ASP C 3 171 ? 102.804 145.560 157.750 1.00 244.62 ? 171 ASP L N   1 
ATOM   8475  C  CA  . ASP C 3 171 ? 101.770 144.543 157.844 1.00 239.80 ? 171 ASP L CA  1 
ATOM   8476  C  C   . ASP C 3 171 ? 101.227 144.544 159.278 1.00 204.38 ? 171 ASP L C   1 
ATOM   8477  O  O   . ASP C 3 171 ? 101.878 144.999 160.221 1.00 241.52 ? 171 ASP L O   1 
ATOM   8478  C  CB  . ASP C 3 171 ? 102.312 143.178 157.391 1.00 307.44 ? 171 ASP L CB  1 
ATOM   8479  C  CG  . ASP C 3 171 ? 102.798 143.129 155.947 1.00 373.53 ? 171 ASP L CG  1 
ATOM   8480  O  OD1 . ASP C 3 171 ? 102.760 144.183 155.260 1.00 344.28 ? 171 ASP L OD1 1 
ATOM   8481  O  OD2 . ASP C 3 171 ? 103.213 142.036 155.515 1.00 457.30 ? 171 ASP L OD2 1 
ATOM   8482  N  N   . GLN C 3 172 ? 100.016 144.027 159.441 1.00 174.31 ? 172 GLN L N   1 
ATOM   8483  C  CA  . GLN C 3 172 ? 99.265  144.136 160.689 1.00 193.84 ? 172 GLN L CA  1 
ATOM   8484  C  C   . GLN C 3 172 ? 99.891  143.237 161.764 1.00 168.36 ? 172 GLN L C   1 
ATOM   8485  O  O   . GLN C 3 172 ? 100.212 142.084 161.495 1.00 196.99 ? 172 GLN L O   1 
ATOM   8486  C  CB  . GLN C 3 172 ? 97.821  143.793 160.322 1.00 232.12 ? 172 GLN L CB  1 
ATOM   8487  C  CG  . GLN C 3 172 ? 96.776  144.081 161.376 1.00 194.20 ? 172 GLN L CG  1 
ATOM   8488  C  CD  . GLN C 3 172 ? 95.381  143.930 160.813 1.00 229.76 ? 172 GLN L CD  1 
ATOM   8489  O  OE1 . GLN C 3 172 ? 95.180  143.679 159.623 1.00 253.77 ? 172 GLN L OE1 1 
ATOM   8490  N  NE2 . GLN C 3 172 ? 94.381  144.099 161.664 1.00 259.63 ? 172 GLN L NE2 1 
ATOM   8491  N  N   . ASP C 3 173 ? 100.080 143.753 162.987 1.00 189.75 ? 173 ASP L N   1 
ATOM   8492  C  CA  . ASP C 3 173 ? 100.875 143.077 164.017 1.00 258.22 ? 173 ASP L CA  1 
ATOM   8493  C  C   . ASP C 3 173 ? 100.105 141.895 164.616 1.00 180.66 ? 173 ASP L C   1 
ATOM   8494  O  O   . ASP C 3 173 ? 99.052  142.104 165.206 1.00 252.72 ? 173 ASP L O   1 
ATOM   8495  C  CB  . ASP C 3 173 ? 101.305 144.069 165.116 1.00 338.83 ? 173 ASP L CB  1 
ATOM   8496  C  CG  . ASP C 3 173 ? 101.968 143.504 166.373 1.00 358.69 ? 173 ASP L CG  1 
ATOM   8497  O  OD1 . ASP C 3 173 ? 102.177 142.262 166.454 1.00 382.56 ? 173 ASP L OD1 1 
ATOM   8498  O  OD2 . ASP C 3 173 ? 102.273 144.309 167.284 1.00 315.17 ? 173 ASP L OD2 1 
ATOM   8499  N  N   . SER C 3 174 ? 100.638 140.668 164.520 1.00 172.01 ? 174 SER L N   1 
ATOM   8500  C  CA  . SER C 3 174 ? 99.954  139.461 165.000 1.00 260.03 ? 174 SER L CA  1 
ATOM   8501  C  C   . SER C 3 174 ? 99.663  139.395 166.515 1.00 266.75 ? 174 SER L C   1 
ATOM   8502  O  O   . SER C 3 174 ? 98.852  138.563 166.925 1.00 260.85 ? 174 SER L O   1 
ATOM   8503  C  CB  . SER C 3 174 ? 100.729 138.237 164.581 1.00 294.80 ? 174 SER L CB  1 
ATOM   8504  O  OG  . SER C 3 174 ? 102.079 138.351 165.010 1.00 314.82 ? 174 SER L OG  1 
ATOM   8505  N  N   . LYS C 3 175 ? 100.282 140.225 167.369 1.00 307.91 ? 175 LYS L N   1 
ATOM   8506  C  CA  . LYS C 3 175 ? 99.986  140.210 168.803 1.00 322.86 ? 175 LYS L CA  1 
ATOM   8507  C  C   . LYS C 3 175 ? 98.743  141.037 169.158 1.00 277.16 ? 175 LYS L C   1 
ATOM   8508  O  O   . LYS C 3 175 ? 98.051  140.712 170.124 1.00 281.59 ? 175 LYS L O   1 
ATOM   8509  C  CB  . LYS C 3 175 ? 101.178 140.750 169.601 1.00 410.04 ? 175 LYS L CB  1 
ATOM   8510  C  CG  . LYS C 3 175 ? 102.429 139.881 169.571 1.00 451.23 ? 175 LYS L CG  1 
ATOM   8511  C  CD  . LYS C 3 175 ? 103.650 140.514 170.226 1.00 489.19 ? 175 LYS L CD  1 
ATOM   8512  C  CE  . LYS C 3 175 ? 104.114 141.819 169.603 1.00 538.09 ? 175 LYS L CE  1 
ATOM   8513  N  NZ  . LYS C 3 175 ? 104.368 141.706 168.146 1.00 565.62 ? 175 LYS L NZ  1 
ATOM   8514  N  N   . ASP C 3 176 ? 98.482  142.114 168.394 1.00 257.81 ? 176 ASP L N   1 
ATOM   8515  C  CA  . ASP C 3 176 ? 97.523  143.151 168.765 1.00 256.44 ? 176 ASP L CA  1 
ATOM   8516  C  C   . ASP C 3 176 ? 96.647  143.619 167.594 1.00 197.88 ? 176 ASP L C   1 
ATOM   8517  O  O   . ASP C 3 176 ? 95.741  144.426 167.792 1.00 212.44 ? 176 ASP L O   1 
ATOM   8518  C  CB  . ASP C 3 176 ? 98.306  144.316 169.384 1.00 336.03 ? 176 ASP L CB  1 
ATOM   8519  C  CG  . ASP C 3 176 ? 97.541  145.249 170.317 1.00 443.71 ? 176 ASP L CG  1 
ATOM   8520  O  OD1 . ASP C 3 176 ? 96.353  144.985 170.606 1.00 497.92 ? 176 ASP L OD1 1 
ATOM   8521  O  OD2 . ASP C 3 176 ? 98.150  146.245 170.760 1.00 486.49 ? 176 ASP L OD2 1 
ATOM   8522  N  N   . SER C 3 177 ? 96.909  143.126 166.376 1.00 216.32 ? 177 SER L N   1 
ATOM   8523  C  CA  . SER C 3 177 ? 96.142  143.386 165.166 1.00 210.09 ? 177 SER L CA  1 
ATOM   8524  C  C   . SER C 3 177 ? 96.100  144.876 164.785 1.00 216.31 ? 177 SER L C   1 
ATOM   8525  O  O   . SER C 3 177 ? 95.191  145.291 164.058 1.00 200.04 ? 177 SER L O   1 
ATOM   8526  C  CB  . SER C 3 177 ? 94.787  142.773 165.283 1.00 221.92 ? 177 SER L CB  1 
ATOM   8527  O  OG  . SER C 3 177 ? 94.921  141.382 165.512 1.00 205.66 ? 177 SER L OG  1 
ATOM   8528  N  N   . THR C 3 178 ? 97.096  145.670 165.232 1.00 209.06 ? 178 THR L N   1 
ATOM   8529  C  CA  . THR C 3 178 ? 97.225  147.068 164.836 1.00 184.75 ? 178 THR L CA  1 
ATOM   8530  C  C   . THR C 3 178 ? 98.185  147.239 163.658 1.00 184.17 ? 178 THR L C   1 
ATOM   8531  O  O   . THR C 3 178 ? 99.129  146.466 163.503 1.00 244.73 ? 178 THR L O   1 
ATOM   8532  C  CB  . THR C 3 178 ? 97.761  147.939 165.976 1.00 197.09 ? 178 THR L CB  1 
ATOM   8533  O  OG1 . THR C 3 178 ? 99.046  147.466 166.384 1.00 198.53 ? 178 THR L OG1 1 
ATOM   8534  C  CG2 . THR C 3 178 ? 96.848  147.961 167.180 1.00 231.36 ? 178 THR L CG2 1 
ATOM   8535  N  N   . TYR C 3 179 ? 97.944  148.273 162.845 1.00 160.49 ? 179 TYR L N   1 
ATOM   8536  C  CA  . TYR C 3 179 ? 98.942  148.758 161.904 1.00 176.32 ? 179 TYR L CA  1 
ATOM   8537  C  C   . TYR C 3 179 ? 99.875  149.749 162.606 1.00 194.99 ? 179 TYR L C   1 
ATOM   8538  O  O   . TYR C 3 179 ? 99.578  150.255 163.684 1.00 210.43 ? 179 TYR L O   1 
ATOM   8539  C  CB  . TYR C 3 179 ? 98.274  149.449 160.717 1.00 177.66 ? 179 TYR L CB  1 
ATOM   8540  C  CG  . TYR C 3 179 ? 97.469  148.474 159.880 1.00 173.83 ? 179 TYR L CG  1 
ATOM   8541  C  CD1 . TYR C 3 179 ? 96.202  148.063 160.262 1.00 170.10 ? 179 TYR L CD1 1 
ATOM   8542  C  CD2 . TYR C 3 179 ? 97.984  147.958 158.698 1.00 254.36 ? 179 TYR L CD2 1 
ATOM   8543  C  CE1 . TYR C 3 179 ? 95.474  147.175 159.484 1.00 248.77 ? 179 TYR L CE1 1 
ATOM   8544  C  CE2 . TYR C 3 179 ? 97.266  147.065 157.911 1.00 282.61 ? 179 TYR L CE2 1 
ATOM   8545  C  CZ  . TYR C 3 179 ? 96.001  146.670 158.306 1.00 270.10 ? 179 TYR L CZ  1 
ATOM   8546  O  OH  . TYR C 3 179 ? 95.262  145.790 157.567 1.00 244.61 ? 179 TYR L OH  1 
ATOM   8547  N  N   . SER C 3 180 ? 101.020 150.027 161.967 1.00 187.14 ? 180 SER L N   1 
ATOM   8548  C  CA  . SER C 3 180 ? 101.888 151.162 162.266 1.00 165.45 ? 180 SER L CA  1 
ATOM   8549  C  C   . SER C 3 180 ? 102.424 151.712 160.947 1.00 148.65 ? 180 SER L C   1 
ATOM   8550  O  O   . SER C 3 180 ? 102.465 150.976 159.960 1.00 154.93 ? 180 SER L O   1 
ATOM   8551  C  CB  . SER C 3 180 ? 103.026 150.776 163.175 1.00 229.66 ? 180 SER L CB  1 
ATOM   8552  O  OG  . SER C 3 180 ? 102.567 150.420 164.472 1.00 263.31 ? 180 SER L OG  1 
ATOM   8553  N  N   . MET C 3 181 ? 102.837 152.988 160.927 1.00 172.33 ? 181 MET L N   1 
ATOM   8554  C  CA  . MET C 3 181 ? 103.321 153.606 159.697 1.00 198.07 ? 181 MET L CA  1 
ATOM   8555  C  C   . MET C 3 181 ? 104.469 154.568 159.995 1.00 196.70 ? 181 MET L C   1 
ATOM   8556  O  O   . MET C 3 181 ? 104.444 155.291 160.986 1.00 212.00 ? 181 MET L O   1 
ATOM   8557  C  CB  . MET C 3 181 ? 102.220 154.384 158.965 1.00 207.94 ? 181 MET L CB  1 
ATOM   8558  C  CG  . MET C 3 181 ? 102.558 154.605 157.503 1.00 191.45 ? 181 MET L CG  1 
ATOM   8559  S  SD  . MET C 3 181 ? 101.533 155.811 156.671 1.00 211.79 ? 181 MET L SD  1 
ATOM   8560  C  CE  . MET C 3 181 ? 102.552 157.256 156.940 1.00 279.37 ? 181 MET L CE  1 
ATOM   8561  N  N   . SER C 3 182 ? 105.465 154.555 159.107 1.00 181.95 ? 182 SER L N   1 
ATOM   8562  C  CA  . SER C 3 182 ? 106.548 155.514 159.100 1.00 205.39 ? 182 SER L CA  1 
ATOM   8563  C  C   . SER C 3 182 ? 106.323 156.496 157.961 1.00 228.95 ? 182 SER L C   1 
ATOM   8564  O  O   . SER C 3 182 ? 105.942 156.077 156.861 1.00 173.11 ? 182 SER L O   1 
ATOM   8565  C  CB  . SER C 3 182 ? 107.857 154.800 158.943 1.00 285.82 ? 182 SER L CB  1 
ATOM   8566  O  OG  . SER C 3 182 ? 108.922 155.685 158.648 1.00 323.02 ? 182 SER L OG  1 
ATOM   8567  N  N   . SER C 3 183 ? 106.575 157.784 158.259 1.00 267.49 ? 183 SER L N   1 
ATOM   8568  C  CA  . SER C 3 183 ? 106.621 158.842 157.262 1.00 279.56 ? 183 SER L CA  1 
ATOM   8569  C  C   . SER C 3 183 ? 107.973 159.558 157.313 1.00 273.26 ? 183 SER L C   1 
ATOM   8570  O  O   . SER C 3 183 ? 108.497 159.822 158.393 1.00 214.38 ? 183 SER L O   1 
ATOM   8571  C  CB  . SER C 3 183 ? 105.490 159.794 157.460 1.00 290.54 ? 183 SER L CB  1 
ATOM   8572  O  OG  . SER C 3 183 ? 105.397 160.664 156.343 1.00 309.58 ? 183 SER L OG  1 
ATOM   8573  N  N   . THR C 3 184 ? 108.527 159.868 156.130 1.00 282.88 ? 184 THR L N   1 
ATOM   8574  C  CA  . THR C 3 184 ? 109.896 160.348 155.984 1.00 292.85 ? 184 THR L CA  1 
ATOM   8575  C  C   . THR C 3 184 ? 109.914 161.550 155.047 1.00 289.70 ? 184 THR L C   1 
ATOM   8576  O  O   . THR C 3 184 ? 109.266 161.506 154.008 1.00 270.51 ? 184 THR L O   1 
ATOM   8577  C  CB  . THR C 3 184 ? 110.822 159.261 155.422 1.00 354.83 ? 184 THR L CB  1 
ATOM   8578  O  OG1 . THR C 3 184 ? 110.850 158.141 156.306 1.00 364.36 ? 184 THR L OG1 1 
ATOM   8579  C  CG2 . THR C 3 184 ? 112.253 159.721 155.228 1.00 367.02 ? 184 THR L CG2 1 
ATOM   8580  N  N   . LEU C 3 185 ? 110.664 162.594 155.431 1.00 291.13 ? 185 LEU L N   1 
ATOM   8581  C  CA  . LEU C 3 185 ? 110.924 163.764 154.605 1.00 307.07 ? 185 LEU L CA  1 
ATOM   8582  C  C   . LEU C 3 185 ? 112.438 163.955 154.498 1.00 341.40 ? 185 LEU L C   1 
ATOM   8583  O  O   . LEU C 3 185 ? 113.096 164.073 155.527 1.00 303.65 ? 185 LEU L O   1 
ATOM   8584  C  CB  . LEU C 3 185 ? 110.232 164.964 155.264 1.00 287.45 ? 185 LEU L CB  1 
ATOM   8585  C  CG  . LEU C 3 185 ? 110.590 166.346 154.724 1.00 312.50 ? 185 LEU L CG  1 
ATOM   8586  C  CD1 . LEU C 3 185 ? 110.333 166.443 153.224 1.00 336.82 ? 185 LEU L CD1 1 
ATOM   8587  C  CD2 . LEU C 3 185 ? 109.814 167.415 155.475 1.00 301.52 ? 185 LEU L CD2 1 
ATOM   8588  N  N   . THR C 3 186 ? 112.986 163.987 153.265 1.00 388.48 ? 186 THR L N   1 
ATOM   8589  C  CA  . THR C 3 186 ? 114.425 164.146 153.051 1.00 410.13 ? 186 THR L CA  1 
ATOM   8590  C  C   . THR C 3 186 ? 114.724 165.521 152.439 1.00 374.87 ? 186 THR L C   1 
ATOM   8591  O  O   . THR C 3 186 ? 114.092 165.941 151.463 1.00 240.34 ? 186 THR L O   1 
ATOM   8592  C  CB  . THR C 3 186 ? 115.024 162.999 152.221 1.00 408.17 ? 186 THR L CB  1 
ATOM   8593  O  OG1 . THR C 3 186 ? 114.986 161.813 153.018 1.00 340.80 ? 186 THR L OG1 1 
ATOM   8594  C  CG2 . THR C 3 186 ? 116.461 163.236 151.802 1.00 413.14 ? 186 THR L CG2 1 
ATOM   8595  N  N   . LEU C 3 187 ? 115.727 166.188 153.042 1.00 374.36 ? 187 LEU L N   1 
ATOM   8596  C  CA  . LEU C 3 187 ? 116.110 167.568 152.785 1.00 350.40 ? 187 LEU L CA  1 
ATOM   8597  C  C   . LEU C 3 187 ? 117.611 167.631 152.474 1.00 352.80 ? 187 LEU L C   1 
ATOM   8598  O  O   . LEU C 3 187 ? 118.381 166.774 152.919 1.00 224.57 ? 187 LEU L O   1 
ATOM   8599  C  CB  . LEU C 3 187 ? 115.817 168.403 154.043 1.00 358.48 ? 187 LEU L CB  1 
ATOM   8600  C  CG  . LEU C 3 187 ? 114.426 168.299 154.675 1.00 323.80 ? 187 LEU L CG  1 
ATOM   8601  C  CD1 . LEU C 3 187 ? 114.356 169.097 155.977 1.00 307.37 ? 187 LEU L CD1 1 
ATOM   8602  C  CD2 . LEU C 3 187 ? 113.354 168.774 153.706 1.00 343.87 ? 187 LEU L CD2 1 
ATOM   8603  N  N   . THR C 3 188 ? 118.054 168.661 151.733 1.00 395.18 ? 188 THR L N   1 
ATOM   8604  C  CA  . THR C 3 188 ? 119.475 169.019 151.732 1.00 397.77 ? 188 THR L CA  1 
ATOM   8605  C  C   . THR C 3 188 ? 119.823 169.645 153.088 1.00 372.22 ? 188 THR L C   1 
ATOM   8606  O  O   . THR C 3 188 ? 118.940 170.100 153.815 1.00 389.76 ? 188 THR L O   1 
ATOM   8607  C  CB  . THR C 3 188 ? 119.893 169.944 150.571 1.00 404.36 ? 188 THR L CB  1 
ATOM   8608  O  OG1 . THR C 3 188 ? 119.504 171.296 150.823 1.00 356.22 ? 188 THR L OG1 1 
ATOM   8609  C  CG2 . THR C 3 188 ? 119.338 169.518 149.227 1.00 421.60 ? 188 THR L CG2 1 
ATOM   8610  N  N   . LYS C 3 189 ? 121.114 169.688 153.440 1.00 349.52 ? 189 LYS L N   1 
ATOM   8611  C  CA  . LYS C 3 189 ? 121.536 170.296 154.700 1.00 333.14 ? 189 LYS L CA  1 
ATOM   8612  C  C   . LYS C 3 189 ? 121.126 171.773 154.737 1.00 329.34 ? 189 LYS L C   1 
ATOM   8613  O  O   . LYS C 3 189 ? 120.601 172.227 155.751 1.00 299.82 ? 189 LYS L O   1 
ATOM   8614  C  CB  . LYS C 3 189 ? 123.041 170.103 154.917 1.00 356.24 ? 189 LYS L CB  1 
ATOM   8615  C  CG  . LYS C 3 189 ? 123.569 170.557 156.272 1.00 343.08 ? 189 LYS L CG  1 
ATOM   8616  C  CD  . LYS C 3 189 ? 125.052 170.309 156.430 1.00 364.13 ? 189 LYS L CD  1 
ATOM   8617  C  CE  . LYS C 3 189 ? 125.583 170.631 157.811 1.00 372.23 ? 189 LYS L CE  1 
ATOM   8618  N  NZ  . LYS C 3 189 ? 125.809 172.083 157.999 1.00 393.07 ? 189 LYS L NZ  1 
ATOM   8619  N  N   . ASP C 3 190 ? 121.346 172.505 153.630 1.00 397.57 ? 190 ASP L N   1 
ATOM   8620  C  CA  . ASP C 3 190 ? 121.004 173.922 153.519 1.00 469.41 ? 190 ASP L CA  1 
ATOM   8621  C  C   . ASP C 3 190 ? 119.484 174.160 153.506 1.00 466.30 ? 190 ASP L C   1 
ATOM   8622  O  O   . ASP C 3 190 ? 119.031 175.246 153.875 1.00 486.44 ? 190 ASP L O   1 
ATOM   8623  C  CB  . ASP C 3 190 ? 121.657 174.541 152.274 1.00 510.84 ? 190 ASP L CB  1 
ATOM   8624  C  CG  . ASP C 3 190 ? 123.179 174.491 152.224 1.00 524.76 ? 190 ASP L CG  1 
ATOM   8625  O  OD1 . ASP C 3 190 ? 123.806 174.164 153.255 1.00 538.30 ? 190 ASP L OD1 1 
ATOM   8626  O  OD2 . ASP C 3 190 ? 123.732 174.782 151.142 1.00 520.13 ? 190 ASP L OD2 1 
ATOM   8627  N  N   . GLU C 3 191 ? 118.700 173.157 153.075 1.00 414.40 ? 191 GLU L N   1 
ATOM   8628  C  CA  . GLU C 3 191 ? 117.240 173.158 153.153 1.00 382.55 ? 191 GLU L CA  1 
ATOM   8629  C  C   . GLU C 3 191 ? 116.756 172.920 154.592 1.00 332.12 ? 191 GLU L C   1 
ATOM   8630  O  O   . GLU C 3 191 ? 115.743 173.491 154.991 1.00 298.17 ? 191 GLU L O   1 
ATOM   8631  C  CB  . GLU C 3 191 ? 116.732 172.109 152.160 1.00 378.10 ? 191 GLU L CB  1 
ATOM   8632  C  CG  . GLU C 3 191 ? 115.229 171.978 152.029 1.00 405.44 ? 191 GLU L CG  1 
ATOM   8633  C  CD  . GLU C 3 191 ? 114.813 170.970 150.967 1.00 447.67 ? 191 GLU L CD  1 
ATOM   8634  O  OE1 . GLU C 3 191 ? 115.646 170.101 150.596 1.00 459.58 ? 191 GLU L OE1 1 
ATOM   8635  O  OE2 . GLU C 3 191 ? 113.660 171.058 150.503 1.00 484.60 ? 191 GLU L OE2 1 
ATOM   8636  N  N   . TYR C 3 192 ? 117.465 172.080 155.366 1.00 304.04 ? 192 TYR L N   1 
ATOM   8637  C  CA  . TYR C 3 192 ? 117.221 171.916 156.800 1.00 312.85 ? 192 TYR L CA  1 
ATOM   8638  C  C   . TYR C 3 192 ? 117.742 173.120 157.617 1.00 387.80 ? 192 TYR L C   1 
ATOM   8639  O  O   . TYR C 3 192 ? 117.280 173.353 158.739 1.00 414.31 ? 192 TYR L O   1 
ATOM   8640  C  CB  . TYR C 3 192 ? 117.812 170.569 157.253 1.00 321.92 ? 192 TYR L CB  1 
ATOM   8641  C  CG  . TYR C 3 192 ? 117.784 170.367 158.766 1.00 325.84 ? 192 TYR L CG  1 
ATOM   8642  C  CD1 . TYR C 3 192 ? 116.578 170.355 159.464 1.00 259.23 ? 192 TYR L CD1 1 
ATOM   8643  C  CD2 . TYR C 3 192 ? 118.958 170.208 159.505 1.00 389.88 ? 192 TYR L CD2 1 
ATOM   8644  C  CE1 . TYR C 3 192 ? 116.540 170.187 160.845 1.00 268.60 ? 192 TYR L CE1 1 
ATOM   8645  C  CE2 . TYR C 3 192 ? 118.933 170.039 160.886 1.00 387.59 ? 192 TYR L CE2 1 
ATOM   8646  C  CZ  . TYR C 3 192 ? 117.720 170.031 161.562 1.00 318.79 ? 192 TYR L CZ  1 
ATOM   8647  O  OH  . TYR C 3 192 ? 117.674 169.855 162.921 1.00 245.45 ? 192 TYR L OH  1 
ATOM   8648  N  N   . GLU C 3 193 ? 118.705 173.893 157.083 1.00 426.77 ? 193 GLU L N   1 
ATOM   8649  C  CA  . GLU C 3 193 ? 119.298 175.035 157.780 1.00 428.37 ? 193 GLU L CA  1 
ATOM   8650  C  C   . GLU C 3 193 ? 118.385 176.264 157.739 1.00 389.36 ? 193 GLU L C   1 
ATOM   8651  O  O   . GLU C 3 193 ? 118.227 176.939 158.759 1.00 358.72 ? 193 GLU L O   1 
ATOM   8652  C  CB  . GLU C 3 193 ? 120.673 175.351 157.180 1.00 479.50 ? 193 GLU L CB  1 
ATOM   8653  C  CG  . GLU C 3 193 ? 121.592 176.125 158.116 1.00 506.92 ? 193 GLU L CG  1 
ATOM   8654  C  CD  . GLU C 3 193 ? 122.147 175.362 159.311 1.00 523.93 ? 193 GLU L CD  1 
ATOM   8655  O  OE1 . GLU C 3 193 ? 121.898 174.141 159.422 1.00 505.72 ? 193 GLU L OE1 1 
ATOM   8656  O  OE2 . GLU C 3 193 ? 122.833 175.996 160.138 1.00 558.83 ? 193 GLU L OE2 1 
ATOM   8657  N  N   . ARG C 3 194 ? 117.795 176.545 156.565 1.00 375.70 ? 194 ARG L N   1 
ATOM   8658  C  CA  . ARG C 3 194 ? 117.063 177.782 156.301 1.00 373.30 ? 194 ARG L CA  1 
ATOM   8659  C  C   . ARG C 3 194 ? 115.696 177.856 157.000 1.00 386.73 ? 194 ARG L C   1 
ATOM   8660  O  O   . ARG C 3 194 ? 115.128 178.948 157.048 1.00 399.95 ? 194 ARG L O   1 
ATOM   8661  C  CB  . ARG C 3 194 ? 116.896 177.977 154.785 1.00 357.34 ? 194 ARG L CB  1 
ATOM   8662  C  CG  . ARG C 3 194 ? 116.043 176.928 154.080 1.00 387.92 ? 194 ARG L CG  1 
ATOM   8663  C  CD  . ARG C 3 194 ? 116.081 177.075 152.575 1.00 420.44 ? 194 ARG L CD  1 
ATOM   8664  N  NE  . ARG C 3 194 ? 117.418 176.865 152.036 1.00 444.95 ? 194 ARG L NE  1 
ATOM   8665  C  CZ  . ARG C 3 194 ? 117.793 177.148 150.793 1.00 463.60 ? 194 ARG L CZ  1 
ATOM   8666  N  NH1 . ARG C 3 194 ? 119.053 176.981 150.427 1.00 499.75 ? 194 ARG L NH1 1 
ATOM   8667  N  NH2 . ARG C 3 194 ? 116.917 177.601 149.909 1.00 435.62 ? 194 ARG L NH2 1 
ATOM   8668  N  N   . HIS C 3 195 ? 115.168 176.730 157.526 1.00 367.19 ? 195 HIS L N   1 
ATOM   8669  C  CA  . HIS C 3 195 ? 113.869 176.674 158.196 1.00 329.90 ? 195 HIS L CA  1 
ATOM   8670  C  C   . HIS C 3 195 ? 114.014 176.134 159.627 1.00 285.54 ? 195 HIS L C   1 
ATOM   8671  O  O   . HIS C 3 195 ? 114.886 175.310 159.901 1.00 289.23 ? 195 HIS L O   1 
ATOM   8672  C  CB  . HIS C 3 195 ? 112.894 175.866 157.323 1.00 352.86 ? 195 HIS L CB  1 
ATOM   8673  C  CG  . HIS C 3 195 ? 112.547 176.496 156.002 1.00 361.38 ? 195 HIS L CG  1 
ATOM   8674  N  ND1 . HIS C 3 195 ? 112.254 175.802 154.844 1.00 361.54 ? 195 HIS L ND1 1 
ATOM   8675  C  CD2 . HIS C 3 195 ? 112.438 177.791 155.683 1.00 365.66 ? 195 HIS L CD2 1 
ATOM   8676  C  CE1 . HIS C 3 195 ? 111.986 176.656 153.866 1.00 317.83 ? 195 HIS L CE1 1 
ATOM   8677  N  NE2 . HIS C 3 195 ? 112.093 177.871 154.355 1.00 345.30 ? 195 HIS L NE2 1 
ATOM   8678  N  N   . ASN C 3 196 ? 113.144 176.598 160.541 1.00 264.06 ? 196 ASN L N   1 
ATOM   8679  C  CA  . ASN C 3 196 ? 113.343 176.487 161.985 1.00 308.17 ? 196 ASN L CA  1 
ATOM   8680  C  C   . ASN C 3 196 ? 112.436 175.446 162.663 1.00 340.18 ? 196 ASN L C   1 
ATOM   8681  O  O   . ASN C 3 196 ? 112.916 174.698 163.527 1.00 292.28 ? 196 ASN L O   1 
ATOM   8682  C  CB  . ASN C 3 196 ? 113.147 177.863 162.627 1.00 371.36 ? 196 ASN L CB  1 
ATOM   8683  C  CG  . ASN C 3 196 ? 113.280 177.862 164.137 1.00 372.80 ? 196 ASN L CG  1 
ATOM   8684  O  OD1 . ASN C 3 196 ? 112.268 177.803 164.832 1.00 391.88 ? 196 ASN L OD1 1 
ATOM   8685  N  ND2 . ASN C 3 196 ? 114.502 177.920 164.649 1.00 331.92 ? 196 ASN L ND2 1 
ATOM   8686  N  N   . SER C 3 197 ? 111.136 175.412 162.293 1.00 365.84 ? 197 SER L N   1 
ATOM   8687  C  CA  . SER C 3 197 ? 110.101 174.635 162.976 1.00 348.35 ? 197 SER L CA  1 
ATOM   8688  C  C   . SER C 3 197 ? 109.484 173.579 162.053 1.00 342.34 ? 197 SER L C   1 
ATOM   8689  O  O   . SER C 3 197 ? 108.909 173.920 161.016 1.00 309.04 ? 197 SER L O   1 
ATOM   8690  C  CB  . SER C 3 197 ? 109.030 175.546 163.515 1.00 313.16 ? 197 SER L CB  1 
ATOM   8691  O  OG  . SER C 3 197 ? 108.125 174.828 164.344 1.00 295.31 ? 197 SER L OG  1 
ATOM   8692  N  N   . TYR C 3 198 ? 109.598 172.298 162.451 1.00 314.51 ? 198 TYR L N   1 
ATOM   8693  C  CA  . TYR C 3 198 ? 109.163 171.155 161.659 1.00 283.95 ? 198 TYR L CA  1 
ATOM   8694  C  C   . TYR C 3 198 ? 108.003 170.454 162.365 1.00 293.80 ? 198 TYR L C   1 
ATOM   8695  O  O   . TYR C 3 198 ? 108.090 170.186 163.564 1.00 174.55 ? 198 TYR L O   1 
ATOM   8696  C  CB  . TYR C 3 198 ? 110.353 170.217 161.451 1.00 255.00 ? 198 TYR L CB  1 
ATOM   8697  C  CG  . TYR C 3 198 ? 111.449 170.885 160.643 1.00 250.96 ? 198 TYR L CG  1 
ATOM   8698  C  CD1 . TYR C 3 198 ? 111.471 170.830 159.249 1.00 283.73 ? 198 TYR L CD1 1 
ATOM   8699  C  CD2 . TYR C 3 198 ? 112.454 171.589 161.287 1.00 277.11 ? 198 TYR L CD2 1 
ATOM   8700  C  CE1 . TYR C 3 198 ? 112.480 171.447 158.521 1.00 313.77 ? 198 TYR L CE1 1 
ATOM   8701  C  CE2 . TYR C 3 198 ? 113.462 172.219 160.570 1.00 359.70 ? 198 TYR L CE2 1 
ATOM   8702  C  CZ  . TYR C 3 198 ? 113.476 172.149 159.183 1.00 350.32 ? 198 TYR L CZ  1 
ATOM   8703  O  OH  . TYR C 3 198 ? 114.462 172.770 158.475 1.00 340.14 ? 198 TYR L OH  1 
ATOM   8704  N  N   . THR C 3 199 ? 106.930 170.160 161.605 1.00 305.37 ? 199 THR L N   1 
ATOM   8705  C  CA  . THR C 3 199 ? 105.689 169.605 162.131 1.00 296.86 ? 199 THR L CA  1 
ATOM   8706  C  C   . THR C 3 199 ? 105.255 168.390 161.305 1.00 315.42 ? 199 THR L C   1 
ATOM   8707  O  O   . THR C 3 199 ? 105.252 168.442 160.077 1.00 276.26 ? 199 THR L O   1 
ATOM   8708  C  CB  . THR C 3 199 ? 104.580 170.665 162.137 1.00 284.85 ? 199 THR L CB  1 
ATOM   8709  O  OG1 . THR C 3 199 ? 104.959 171.740 162.997 1.00 268.88 ? 199 THR L OG1 1 
ATOM   8710  C  CG2 . THR C 3 199 ? 103.242 170.132 162.604 1.00 296.79 ? 199 THR L CG2 1 
ATOM   8711  N  N   . CYS C 3 200 ? 104.881 167.304 161.999 1.00 317.25 ? 200 CYS L N   1 
ATOM   8712  C  CA  . CYS C 3 200 ? 104.177 166.162 161.434 1.00 301.09 ? 200 CYS L CA  1 
ATOM   8713  C  C   . CYS C 3 200 ? 102.786 166.119 162.065 1.00 292.45 ? 200 CYS L C   1 
ATOM   8714  O  O   . CYS C 3 200 ? 102.682 166.096 163.294 1.00 284.17 ? 200 CYS L O   1 
ATOM   8715  C  CB  . CYS C 3 200 ? 104.967 164.888 161.719 1.00 310.32 ? 200 CYS L CB  1 
ATOM   8716  S  SG  . CYS C 3 200 ? 104.157 163.335 161.255 1.00 404.06 ? 200 CYS L SG  1 
ATOM   8717  N  N   . GLU C 3 201 ? 101.724 166.119 161.241 1.00 296.90 ? 201 GLU L N   1 
ATOM   8718  C  CA  . GLU C 3 201 ? 100.367 166.022 161.768 1.00 318.22 ? 201 GLU L CA  1 
ATOM   8719  C  C   . GLU C 3 201 ? 99.579  164.962 160.987 1.00 307.61 ? 201 GLU L C   1 
ATOM   8720  O  O   . GLU C 3 201 ? 99.620  164.902 159.757 1.00 272.19 ? 201 GLU L O   1 
ATOM   8721  C  CB  . GLU C 3 201 ? 99.713  167.412 161.840 1.00 360.60 ? 201 GLU L CB  1 
ATOM   8722  C  CG  . GLU C 3 201 ? 99.472  168.131 160.514 1.00 400.75 ? 201 GLU L CG  1 
ATOM   8723  C  CD  . GLU C 3 201 ? 99.136  169.617 160.614 1.00 402.13 ? 201 GLU L CD  1 
ATOM   8724  O  OE1 . GLU C 3 201 ? 99.147  170.171 161.736 1.00 390.47 ? 201 GLU L OE1 1 
ATOM   8725  O  OE2 . GLU C 3 201 ? 98.861  170.231 159.561 1.00 368.03 ? 201 GLU L OE2 1 
ATOM   8726  N  N   . ALA C 3 202 ? 98.856  164.114 161.737 1.00 288.25 ? 202 ALA L N   1 
ATOM   8727  C  CA  . ALA C 3 202 ? 98.270  162.886 161.222 1.00 269.17 ? 202 ALA L CA  1 
ATOM   8728  C  C   . ALA C 3 202 ? 96.757  162.914 161.415 1.00 261.57 ? 202 ALA L C   1 
ATOM   8729  O  O   . ALA C 3 202 ? 96.296  163.173 162.532 1.00 252.17 ? 202 ALA L O   1 
ATOM   8730  C  CB  . ALA C 3 202 ? 98.883  161.710 161.936 1.00 285.12 ? 202 ALA L CB  1 
ATOM   8731  N  N   . THR C 3 203 ? 96.007  162.656 160.327 1.00 290.15 ? 203 THR L N   1 
ATOM   8732  C  CA  . THR C 3 203 ? 94.555  162.557 160.388 1.00 328.93 ? 203 THR L CA  1 
ATOM   8733  C  C   . THR C 3 203 ? 94.154  161.089 160.267 1.00 280.98 ? 203 THR L C   1 
ATOM   8734  O  O   . THR C 3 203 ? 94.508  160.425 159.290 1.00 241.69 ? 203 THR L O   1 
ATOM   8735  C  CB  . THR C 3 203 ? 93.852  163.389 159.307 1.00 388.64 ? 203 THR L CB  1 
ATOM   8736  O  OG1 . THR C 3 203 ? 94.384  164.715 159.290 1.00 385.46 ? 203 THR L OG1 1 
ATOM   8737  C  CG2 . THR C 3 203 ? 92.354  163.462 159.516 1.00 414.78 ? 203 THR L CG2 1 
ATOM   8738  N  N   . HIS C 3 204 ? 93.409  160.610 161.271 1.00 273.05 ? 204 HIS L N   1 
ATOM   8739  C  CA  . HIS C 3 204 ? 92.944  159.235 161.339 1.00 311.20 ? 204 HIS L CA  1 
ATOM   8740  C  C   . HIS C 3 204 ? 91.480  159.231 161.769 1.00 325.25 ? 204 HIS L C   1 
ATOM   8741  O  O   . HIS C 3 204 ? 91.089  160.061 162.583 1.00 345.11 ? 204 HIS L O   1 
ATOM   8742  C  CB  . HIS C 3 204 ? 93.794  158.435 162.334 1.00 338.80 ? 204 HIS L CB  1 
ATOM   8743  C  CG  . HIS C 3 204 ? 93.405  157.003 162.295 1.00 336.87 ? 204 HIS L CG  1 
ATOM   8744  N  ND1 . HIS C 3 204 ? 92.447  156.464 163.118 1.00 332.15 ? 204 HIS L ND1 1 
ATOM   8745  C  CD2 . HIS C 3 204 ? 93.815  156.013 161.502 1.00 309.58 ? 204 HIS L CD2 1 
ATOM   8746  C  CE1 . HIS C 3 204 ? 92.312  155.184 162.826 1.00 302.73 ? 204 HIS L CE1 1 
ATOM   8747  N  NE2 . HIS C 3 204 ? 93.137  154.881 161.851 1.00 237.99 ? 204 HIS L NE2 1 
ATOM   8748  N  N   . LYS C 3 205 ? 90.675  158.281 161.260 1.00 327.58 ? 205 LYS L N   1 
ATOM   8749  C  CA  . LYS C 3 205 ? 89.217  158.324 161.395 1.00 331.83 ? 205 LYS L CA  1 
ATOM   8750  C  C   . LYS C 3 205 ? 88.698  158.290 162.845 1.00 307.67 ? 205 LYS L C   1 
ATOM   8751  O  O   . LYS C 3 205 ? 87.507  158.518 163.050 1.00 335.93 ? 205 LYS L O   1 
ATOM   8752  C  CB  . LYS C 3 205 ? 88.572  157.174 160.610 1.00 340.82 ? 205 LYS L CB  1 
ATOM   8753  C  CG  . LYS C 3 205 ? 88.872  155.763 161.111 1.00 378.61 ? 205 LYS L CG  1 
ATOM   8754  C  CD  . LYS C 3 205 ? 87.818  154.739 160.733 1.00 374.91 ? 205 LYS L CD  1 
ATOM   8755  C  CE  . LYS C 3 205 ? 86.457  155.025 161.332 1.00 340.86 ? 205 LYS L CE  1 
ATOM   8756  N  NZ  . LYS C 3 205 ? 85.675  153.782 161.517 1.00 366.46 ? 205 LYS L NZ  1 
ATOM   8757  N  N   . THR C 3 206 ? 89.559  158.016 163.841 1.00 308.25 ? 206 THR L N   1 
ATOM   8758  C  CA  . THR C 3 206 ? 89.206  158.053 165.258 1.00 325.93 ? 206 THR L CA  1 
ATOM   8759  C  C   . THR C 3 206 ? 89.141  159.463 165.866 1.00 357.52 ? 206 THR L C   1 
ATOM   8760  O  O   . THR C 3 206 ? 88.682  159.589 167.002 1.00 349.85 ? 206 THR L O   1 
ATOM   8761  C  CB  . THR C 3 206 ? 90.199  157.215 166.078 1.00 339.03 ? 206 THR L CB  1 
ATOM   8762  O  OG1 . THR C 3 206 ? 91.534  157.615 165.754 1.00 351.62 ? 206 THR L OG1 1 
ATOM   8763  C  CG2 . THR C 3 206 ? 90.036  155.733 165.835 1.00 325.07 ? 206 THR L CG2 1 
ATOM   8764  N  N   . SER C 3 207 ? 89.587  160.515 165.152 1.00 391.72 ? 207 SER L N   1 
ATOM   8765  C  CA  . SER C 3 207 ? 89.553  161.882 165.665 1.00 409.11 ? 207 SER L CA  1 
ATOM   8766  C  C   . SER C 3 207 ? 89.170  162.876 164.564 1.00 408.77 ? 207 SER L C   1 
ATOM   8767  O  O   . SER C 3 207 ? 89.613  162.749 163.424 1.00 389.60 ? 207 SER L O   1 
ATOM   8768  C  CB  . SER C 3 207 ? 90.880  162.245 166.288 1.00 413.77 ? 207 SER L CB  1 
ATOM   8769  O  OG  . SER C 3 207 ? 90.872  163.574 166.792 1.00 401.20 ? 207 SER L OG  1 
ATOM   8770  N  N   . THR C 3 208 ? 88.348  163.875 164.922 1.00 416.93 ? 208 THR L N   1 
ATOM   8771  C  CA  . THR C 3 208 ? 87.971  164.954 164.016 1.00 440.99 ? 208 THR L CA  1 
ATOM   8772  C  C   . THR C 3 208 ? 89.182  165.846 163.734 1.00 455.53 ? 208 THR L C   1 
ATOM   8773  O  O   . THR C 3 208 ? 89.477  166.125 162.567 1.00 412.64 ? 208 THR L O   1 
ATOM   8774  C  CB  . THR C 3 208 ? 86.807  165.776 164.587 1.00 499.92 ? 208 THR L CB  1 
ATOM   8775  O  OG1 . THR C 3 208 ? 85.746  164.886 164.940 1.00 503.71 ? 208 THR L OG1 1 
ATOM   8776  C  CG2 . THR C 3 208 ? 86.276  166.815 163.622 1.00 542.06 ? 208 THR L CG2 1 
ATOM   8777  N  N   . SER C 3 209 ? 89.854  166.285 164.814 1.00 468.55 ? 209 SER L N   1 
ATOM   8778  C  CA  . SER C 3 209 ? 91.081  167.071 164.746 1.00 441.16 ? 209 SER L CA  1 
ATOM   8779  C  C   . SER C 3 209 ? 92.292  166.177 164.459 1.00 423.14 ? 209 SER L C   1 
ATOM   8780  O  O   . SER C 3 209 ? 92.342  165.041 164.942 1.00 455.70 ? 209 SER L O   1 
ATOM   8781  C  CB  . SER C 3 209 ? 91.293  167.860 166.019 1.00 384.27 ? 209 SER L CB  1 
ATOM   8782  O  OG  . SER C 3 209 ? 91.244  167.013 167.159 1.00 290.70 ? 209 SER L OG  1 
ATOM   8783  N  N   . PRO C 3 210 ? 93.305  166.640 163.674 1.00 375.37 ? 210 PRO L N   1 
ATOM   8784  C  CA  . PRO C 3 210 ? 94.575  165.916 163.551 1.00 372.70 ? 210 PRO L CA  1 
ATOM   8785  C  C   . PRO C 3 210 ? 95.351  165.836 164.864 1.00 332.36 ? 210 PRO L C   1 
ATOM   8786  O  O   . PRO C 3 210 ? 95.230  166.719 165.714 1.00 286.01 ? 210 PRO L O   1 
ATOM   8787  C  CB  . PRO C 3 210 ? 95.399  166.726 162.534 1.00 384.57 ? 210 PRO L CB  1 
ATOM   8788  C  CG  . PRO C 3 210 ? 94.377  167.594 161.820 1.00 364.38 ? 210 PRO L CG  1 
ATOM   8789  C  CD  . PRO C 3 210 ? 93.299  167.862 162.849 1.00 349.14 ? 210 PRO L CD  1 
ATOM   8790  N  N   . ILE C 3 211 ? 96.141  164.764 165.010 1.00 336.63 ? 211 ILE L N   1 
ATOM   8791  C  CA  . ILE C 3 211 ? 97.135  164.655 166.069 1.00 309.47 ? 211 ILE L CA  1 
ATOM   8792  C  C   . ILE C 3 211 ? 98.403  165.339 165.559 1.00 328.02 ? 211 ILE L C   1 
ATOM   8793  O  O   . ILE C 3 211 ? 98.689  165.254 164.365 1.00 338.32 ? 211 ILE L O   1 
ATOM   8794  C  CB  . ILE C 3 211 ? 97.340  163.176 166.473 1.00 311.37 ? 211 ILE L CB  1 
ATOM   8795  C  CG1 . ILE C 3 211 ? 96.056  162.582 167.065 1.00 335.62 ? 211 ILE L CG1 1 
ATOM   8796  C  CG2 . ILE C 3 211 ? 98.516  163.010 167.428 1.00 308.05 ? 211 ILE L CG2 1 
ATOM   8797  C  CD1 . ILE C 3 211 ? 95.948  161.069 166.993 1.00 329.49 ? 211 ILE L CD1 1 
ATOM   8798  N  N   . VAL C 3 212 ? 99.139  166.009 166.466 1.00 348.86 ? 212 VAL L N   1 
ATOM   8799  C  CA  . VAL C 3 212 ? 100.265 166.865 166.105 1.00 360.36 ? 212 VAL L CA  1 
ATOM   8800  C  C   . VAL C 3 212 ? 101.480 166.523 166.965 1.00 318.91 ? 212 VAL L C   1 
ATOM   8801  O  O   . VAL C 3 212 ? 101.354 166.316 168.172 1.00 262.55 ? 212 VAL L O   1 
ATOM   8802  C  CB  . VAL C 3 212 ? 99.919  168.360 166.255 1.00 381.22 ? 212 VAL L CB  1 
ATOM   8803  C  CG1 . VAL C 3 212 ? 101.130 169.267 166.030 1.00 365.89 ? 212 VAL L CG1 1 
ATOM   8804  C  CG2 . VAL C 3 212 ? 98.773  168.762 165.339 1.00 396.69 ? 212 VAL L CG2 1 
ATOM   8805  N  N   . LYS C 3 213 ? 102.654 166.481 166.313 1.00 322.75 ? 213 LYS L N   1 
ATOM   8806  C  CA  . LYS C 3 213 ? 103.944 166.597 166.978 1.00 350.02 ? 213 LYS L CA  1 
ATOM   8807  C  C   . LYS C 3 213 ? 104.870 167.480 166.135 1.00 325.81 ? 213 LYS L C   1 
ATOM   8808  O  O   . LYS C 3 213 ? 104.739 167.538 164.910 1.00 302.15 ? 213 LYS L O   1 
ATOM   8809  C  CB  . LYS C 3 213 ? 104.581 165.218 167.198 1.00 386.48 ? 213 LYS L CB  1 
ATOM   8810  C  CG  . LYS C 3 213 ? 103.895 164.283 168.190 1.00 377.04 ? 213 LYS L CG  1 
ATOM   8811  C  CD  . LYS C 3 213 ? 104.026 164.713 169.640 1.00 335.65 ? 213 LYS L CD  1 
ATOM   8812  C  CE  . LYS C 3 213 ? 103.472 163.695 170.610 1.00 319.25 ? 213 LYS L CE  1 
ATOM   8813  N  NZ  . LYS C 3 213 ? 103.434 164.236 171.988 1.00 330.39 ? 213 LYS L NZ  1 
ATOM   8814  N  N   . SER C 3 214 ? 105.810 168.162 166.808 1.00 313.25 ? 214 SER L N   1 
ATOM   8815  C  CA  . SER C 3 214 ? 106.689 169.128 166.161 1.00 285.72 ? 214 SER L CA  1 
ATOM   8816  C  C   . SER C 3 214 ? 107.970 169.337 166.973 1.00 296.06 ? 214 SER L C   1 
ATOM   8817  O  O   . SER C 3 214 ? 108.025 168.969 168.154 1.00 208.63 ? 214 SER L O   1 
ATOM   8818  C  CB  . SER C 3 214 ? 105.955 170.435 165.935 1.00 289.35 ? 214 SER L CB  1 
ATOM   8819  O  OG  . SER C 3 214 ? 105.514 170.995 167.165 1.00 315.08 ? 214 SER L OG  1 
ATOM   8820  N  N   . PHE C 3 215 ? 108.988 169.933 166.323 1.00 317.89 ? 215 PHE L N   1 
ATOM   8821  C  CA  . PHE C 3 215 ? 110.203 170.373 167.000 1.00 344.23 ? 215 PHE L CA  1 
ATOM   8822  C  C   . PHE C 3 215 ? 110.784 171.619 166.320 1.00 375.32 ? 215 PHE L C   1 
ATOM   8823  O  O   . PHE C 3 215 ? 110.550 171.863 165.134 1.00 317.65 ? 215 PHE L O   1 
ATOM   8824  C  CB  . PHE C 3 215 ? 111.229 169.234 167.062 1.00 301.12 ? 215 PHE L CB  1 
ATOM   8825  C  CG  . PHE C 3 215 ? 111.870 168.885 165.741 1.00 269.50 ? 215 PHE L CG  1 
ATOM   8826  C  CD1 . PHE C 3 215 ? 111.263 167.990 164.874 1.00 253.45 ? 215 PHE L CD1 1 
ATOM   8827  C  CD2 . PHE C 3 215 ? 113.080 169.458 165.355 1.00 316.08 ? 215 PHE L CD2 1 
ATOM   8828  C  CE1 . PHE C 3 215 ? 111.856 167.664 163.660 1.00 263.00 ? 215 PHE L CE1 1 
ATOM   8829  C  CE2 . PHE C 3 215 ? 113.667 169.138 164.138 1.00 291.82 ? 215 PHE L CE2 1 
ATOM   8830  C  CZ  . PHE C 3 215 ? 113.055 168.241 163.292 1.00 269.73 ? 215 PHE L CZ  1 
ATOM   8831  N  N   . ASN C 3 216 ? 111.551 172.398 167.102 1.00 400.96 ? 216 ASN L N   1 
ATOM   8832  C  CA  . ASN C 3 216 ? 112.281 173.566 166.632 1.00 377.85 ? 216 ASN L CA  1 
ATOM   8833  C  C   . ASN C 3 216 ? 113.778 173.289 166.775 1.00 404.61 ? 216 ASN L C   1 
ATOM   8834  O  O   . ASN C 3 216 ? 114.220 172.936 167.871 1.00 380.61 ? 216 ASN L O   1 
ATOM   8835  C  CB  . ASN C 3 216 ? 111.880 174.829 167.403 1.00 334.67 ? 216 ASN L CB  1 
ATOM   8836  C  CG  . ASN C 3 216 ? 110.381 175.037 167.502 1.00 361.43 ? 216 ASN L CG  1 
ATOM   8837  O  OD1 . ASN C 3 216 ? 109.650 174.772 166.549 1.00 373.12 ? 216 ASN L OD1 1 
ATOM   8838  N  ND2 . ASN C 3 216 ? 109.909 175.502 168.650 1.00 389.68 ? 216 ASN L ND2 1 
ATOM   8839  N  N   . ARG C 3 217 ? 114.554 173.463 165.689 1.00 411.53 ? 217 ARG L N   1 
ATOM   8840  C  CA  . ARG C 3 217 ? 115.960 173.063 165.665 1.00 401.94 ? 217 ARG L CA  1 
ATOM   8841  C  C   . ARG C 3 217 ? 116.802 174.025 166.520 1.00 336.45 ? 217 ARG L C   1 
ATOM   8842  O  O   . ARG C 3 217 ? 118.042 174.012 166.344 1.00 278.08 ? 217 ARG L O   1 
ATOM   8843  C  CB  . ARG C 3 217 ? 116.480 172.958 164.221 1.00 420.22 ? 217 ARG L CB  1 
ATOM   8844  C  CG  . ARG C 3 217 ? 116.473 174.249 163.407 1.00 378.17 ? 217 ARG L CG  1 
ATOM   8845  C  CD  . ARG C 3 217 ? 117.331 174.092 162.164 1.00 364.13 ? 217 ARG L CD  1 
ATOM   8846  N  NE  . ARG C 3 217 ? 118.746 174.105 162.525 1.00 377.59 ? 217 ARG L NE  1 
ATOM   8847  C  CZ  . ARG C 3 217 ? 119.758 173.693 161.758 1.00 396.04 ? 217 ARG L CZ  1 
ATOM   8848  N  NH1 . ARG C 3 217 ? 119.573 173.204 160.542 1.00 417.91 ? 217 ARG L NH1 1 
ATOM   8849  N  NH2 . ARG C 3 217 ? 120.995 173.784 162.223 1.00 393.19 ? 217 ARG L NH2 1 
ATOM   8850  N  N   . GLU D 4 1   ? 114.119 116.685 164.059 1.00 256.96 ? 1   GLU H N   1 
ATOM   8851  C  CA  . GLU D 4 1   ? 114.322 117.870 163.185 1.00 263.12 ? 1   GLU H CA  1 
ATOM   8852  C  C   . GLU D 4 1   ? 114.451 117.435 161.729 1.00 276.09 ? 1   GLU H C   1 
ATOM   8853  O  O   . GLU D 4 1   ? 115.140 116.459 161.454 1.00 312.66 ? 1   GLU H O   1 
ATOM   8854  C  CB  . GLU D 4 1   ? 115.594 118.617 163.583 1.00 273.34 ? 1   GLU H CB  1 
ATOM   8855  C  CG  . GLU D 4 1   ? 115.972 119.737 162.620 1.00 304.14 ? 1   GLU H CG  1 
ATOM   8856  C  CD  . GLU D 4 1   ? 117.181 120.572 163.009 1.00 349.58 ? 1   GLU H CD  1 
ATOM   8857  O  OE1 . GLU D 4 1   ? 118.202 119.978 163.417 1.00 342.83 ? 1   GLU H OE1 1 
ATOM   8858  O  OE2 . GLU D 4 1   ? 117.103 121.819 162.878 1.00 412.45 ? 1   GLU H OE2 1 
ATOM   8859  N  N   . VAL D 4 2   ? 113.794 118.179 160.820 1.00 232.14 ? 2   VAL H N   1 
ATOM   8860  C  CA  . VAL D 4 2   ? 114.167 118.282 159.408 1.00 175.11 ? 2   VAL H CA  1 
ATOM   8861  C  C   . VAL D 4 2   ? 114.329 119.762 159.105 1.00 139.48 ? 2   VAL H C   1 
ATOM   8862  O  O   . VAL D 4 2   ? 113.459 120.544 159.474 1.00 178.04 ? 2   VAL H O   1 
ATOM   8863  C  CB  . VAL D 4 2   ? 113.149 117.614 158.446 1.00 166.14 ? 2   VAL H CB  1 
ATOM   8864  C  CG1 . VAL D 4 2   ? 113.354 118.005 156.992 1.00 113.53 ? 2   VAL H CG1 1 
ATOM   8865  C  CG2 . VAL D 4 2   ? 113.218 116.100 158.590 1.00 197.15 ? 2   VAL H CG2 1 
ATOM   8866  N  N   . GLN D 4 3   ? 115.416 120.140 158.428 1.00 116.25 ? 3   GLN H N   1 
ATOM   8867  C  CA  . GLN D 4 3   ? 115.673 121.556 158.169 1.00 141.56 ? 3   GLN H CA  1 
ATOM   8868  C  C   . GLN D 4 3   ? 116.491 121.749 156.899 1.00 132.57 ? 3   GLN H C   1 
ATOM   8869  O  O   . GLN D 4 3   ? 117.611 121.227 156.785 1.00 104.20 ? 3   GLN H O   1 
ATOM   8870  C  CB  . GLN D 4 3   ? 116.457 122.207 159.309 1.00 202.10 ? 3   GLN H CB  1 
ATOM   8871  C  CG  . GLN D 4 3   ? 116.674 123.722 159.203 1.00 240.26 ? 3   GLN H CG  1 
ATOM   8872  C  CD  . GLN D 4 3   ? 117.908 124.207 159.938 1.00 274.20 ? 3   GLN H CD  1 
ATOM   8873  O  OE1 . GLN D 4 3   ? 118.827 124.792 159.358 1.00 242.21 ? 3   GLN H OE1 1 
ATOM   8874  N  NE2 . GLN D 4 3   ? 117.933 123.950 161.237 1.00 323.46 ? 3   GLN H NE2 1 
ATOM   8875  N  N   . LEU D 4 4   ? 115.903 122.522 155.970 1.00 145.47 ? 4   LEU H N   1 
ATOM   8876  C  CA  . LEU D 4 4   ? 116.573 122.990 154.761 1.00 127.90 ? 4   LEU H CA  1 
ATOM   8877  C  C   . LEU D 4 4   ? 116.992 124.420 155.027 1.00 122.75 ? 4   LEU H C   1 
ATOM   8878  O  O   . LEU D 4 4   ? 116.247 125.152 155.686 1.00 182.51 ? 4   LEU H O   1 
ATOM   8879  C  CB  . LEU D 4 4   ? 115.630 122.939 153.548 1.00 101.30 ? 4   LEU H CB  1 
ATOM   8880  C  CG  . LEU D 4 4   ? 114.860 121.633 153.302 1.00 131.84 ? 4   LEU H CG  1 
ATOM   8881  C  CD1 . LEU D 4 4   ? 114.180 121.650 151.952 1.00 132.20 ? 4   LEU H CD1 1 
ATOM   8882  C  CD2 . LEU D 4 4   ? 115.738 120.379 153.379 1.00 183.68 ? 4   LEU H CD2 1 
ATOM   8883  N  N   . GLN D 4 5   ? 118.162 124.823 154.530 1.00 129.40 ? 5   GLN H N   1 
ATOM   8884  C  CA  . GLN D 4 5   ? 118.554 126.225 154.635 1.00 165.32 ? 5   GLN H CA  1 
ATOM   8885  C  C   . GLN D 4 5   ? 119.305 126.680 153.387 1.00 153.15 ? 5   GLN H C   1 
ATOM   8886  O  O   . GLN D 4 5   ? 119.915 125.861 152.696 1.00 124.87 ? 5   GLN H O   1 
ATOM   8887  C  CB  . GLN D 4 5   ? 119.387 126.478 155.890 1.00 202.61 ? 5   GLN H CB  1 
ATOM   8888  C  CG  . GLN D 4 5   ? 120.699 125.714 155.925 1.00 225.15 ? 5   GLN H CG  1 
ATOM   8889  C  CD  . GLN D 4 5   ? 121.584 126.321 156.978 1.00 268.85 ? 5   GLN H CD  1 
ATOM   8890  O  OE1 . GLN D 4 5   ? 122.553 127.021 156.674 1.00 280.78 ? 5   GLN H OE1 1 
ATOM   8891  N  NE2 . GLN D 4 5   ? 121.229 126.055 158.226 1.00 297.22 ? 5   GLN H NE2 1 
ATOM   8892  N  N   . GLN D 4 6   ? 119.219 128.001 153.159 1.00 167.04 ? 6   GLN H N   1 
ATOM   8893  C  CA  . GLN D 4 6   ? 119.664 128.640 151.940 1.00 153.73 ? 6   GLN H CA  1 
ATOM   8894  C  C   . GLN D 4 6   ? 120.328 129.976 152.247 1.00 154.40 ? 6   GLN H C   1 
ATOM   8895  O  O   . GLN D 4 6   ? 119.999 130.622 153.242 1.00 142.70 ? 6   GLN H O   1 
ATOM   8896  C  CB  . GLN D 4 6   ? 118.502 128.958 151.002 1.00 148.81 ? 6   GLN H CB  1 
ATOM   8897  C  CG  . GLN D 4 6   ? 117.504 127.831 150.732 1.00 151.03 ? 6   GLN H CG  1 
ATOM   8898  C  CD  . GLN D 4 6   ? 116.531 128.227 149.635 1.00 128.07 ? 6   GLN H CD  1 
ATOM   8899  O  OE1 . GLN D 4 6   ? 116.680 127.855 148.478 1.00 201.79 ? 6   GLN H OE1 1 
ATOM   8900  N  NE2 . GLN D 4 6   ? 115.531 129.016 149.942 1.00 114.74 ? 6   GLN H NE2 1 
ATOM   8901  N  N   . SER D 4 7   ? 121.250 130.359 151.354 1.00 174.61 ? 7   SER H N   1 
ATOM   8902  C  CA  . SER D 4 7   ? 121.771 131.712 151.266 1.00 192.81 ? 7   SER H CA  1 
ATOM   8903  C  C   . SER D 4 7   ? 120.619 132.710 151.173 1.00 165.04 ? 7   SER H C   1 
ATOM   8904  O  O   . SER D 4 7   ? 119.562 132.357 150.643 1.00 132.83 ? 7   SER H O   1 
ATOM   8905  C  CB  . SER D 4 7   ? 122.734 131.844 150.099 1.00 268.56 ? 7   SER H CB  1 
ATOM   8906  O  OG  . SER D 4 7   ? 122.095 131.661 148.835 1.00 259.36 ? 7   SER H OG  1 
ATOM   8907  N  N   . GLY D 4 8   ? 120.855 133.927 151.713 1.00 171.06 ? 8   GLY H N   1 
ATOM   8908  C  CA  . GLY D 4 8   ? 119.807 134.898 152.017 1.00 184.59 ? 8   GLY H CA  1 
ATOM   8909  C  C   . GLY D 4 8   ? 119.371 135.726 150.802 1.00 159.64 ? 8   GLY H C   1 
ATOM   8910  O  O   . GLY D 4 8   ? 118.175 136.057 150.605 1.00 102.33 ? 8   GLY H O   1 
ATOM   8911  N  N   . ALA D 4 9   ? 120.372 136.066 149.983 1.00 117.17 ? 9   ALA H N   1 
ATOM   8912  C  CA  . ALA D 4 9   ? 120.220 137.135 149.008 1.00 135.38 ? 9   ALA H CA  1 
ATOM   8913  C  C   . ALA D 4 9   ? 121.241 136.960 147.902 1.00 154.13 ? 9   ALA H C   1 
ATOM   8914  O  O   . ALA D 4 9   ? 122.392 136.583 148.157 1.00 159.71 ? 9   ALA H O   1 
ATOM   8915  C  CB  . ALA D 4 9   ? 120.418 138.479 149.661 1.00 230.16 ? 9   ALA H CB  1 
ATOM   8916  N  N   . GLU D 4 10  ? 120.794 137.253 146.676 1.00 167.94 ? 10  GLU H N   1 
ATOM   8917  C  CA  . GLU D 4 10  ? 121.647 137.186 145.502 1.00 176.64 ? 10  GLU H CA  1 
ATOM   8918  C  C   . GLU D 4 10  ? 121.292 138.354 144.603 1.00 196.63 ? 10  GLU H C   1 
ATOM   8919  O  O   . GLU D 4 10  ? 120.116 138.667 144.413 1.00 141.12 ? 10  GLU H O   1 
ATOM   8920  C  CB  . GLU D 4 10  ? 121.480 135.881 144.727 1.00 169.19 ? 10  GLU H CB  1 
ATOM   8921  C  CG  . GLU D 4 10  ? 121.714 134.621 145.560 1.00 251.05 ? 10  GLU H CG  1 
ATOM   8922  C  CD  . GLU D 4 10  ? 123.089 134.412 146.197 1.00 279.82 ? 10  GLU H CD  1 
ATOM   8923  O  OE1 . GLU D 4 10  ? 124.074 135.083 145.788 1.00 231.67 ? 10  GLU H OE1 1 
ATOM   8924  O  OE2 . GLU D 4 10  ? 123.173 133.563 147.121 1.00 336.63 ? 10  GLU H OE2 1 
ATOM   8925  N  N   . LEU D 4 11  ? 122.343 138.991 144.083 1.00 226.18 ? 11  LEU H N   1 
ATOM   8926  C  CA  . LEU D 4 11  ? 122.191 140.039 143.099 1.00 213.67 ? 11  LEU H CA  1 
ATOM   8927  C  C   . LEU D 4 11  ? 122.727 139.522 141.766 1.00 192.63 ? 11  LEU H C   1 
ATOM   8928  O  O   . LEU D 4 11  ? 123.813 138.929 141.703 1.00 190.59 ? 11  LEU H O   1 
ATOM   8929  C  CB  . LEU D 4 11  ? 122.928 141.283 143.595 1.00 199.02 ? 11  LEU H CB  1 
ATOM   8930  C  CG  . LEU D 4 11  ? 122.883 142.462 142.631 1.00 244.62 ? 11  LEU H CG  1 
ATOM   8931  C  CD1 . LEU D 4 11  ? 121.452 142.891 142.344 1.00 202.29 ? 11  LEU H CD1 1 
ATOM   8932  C  CD2 . LEU D 4 11  ? 123.689 143.613 143.197 1.00 312.75 ? 11  LEU H CD2 1 
ATOM   8933  N  N   . VAL D 4 12  ? 121.948 139.760 140.704 1.00 149.61 ? 12  VAL H N   1 
ATOM   8934  C  CA  . VAL D 4 12  ? 122.298 139.257 139.391 1.00 182.99 ? 12  VAL H CA  1 
ATOM   8935  C  C   . VAL D 4 12  ? 122.224 140.381 138.367 1.00 217.73 ? 12  VAL H C   1 
ATOM   8936  O  O   . VAL D 4 12  ? 121.164 140.987 138.239 1.00 227.35 ? 12  VAL H O   1 
ATOM   8937  C  CB  . VAL D 4 12  ? 121.356 138.108 139.010 1.00 196.20 ? 12  VAL H CB  1 
ATOM   8938  C  CG1 . VAL D 4 12  ? 121.621 137.623 137.583 1.00 270.69 ? 12  VAL H CG1 1 
ATOM   8939  C  CG2 . VAL D 4 12  ? 121.448 136.961 140.016 1.00 209.81 ? 12  VAL H CG2 1 
ATOM   8940  N  N   . LYS D 4 13  ? 123.325 140.650 137.633 1.00 199.82 ? 13  LYS H N   1 
ATOM   8941  C  CA  . LYS D 4 13  ? 123.260 141.598 136.522 1.00 203.24 ? 13  LYS H CA  1 
ATOM   8942  C  C   . LYS D 4 13  ? 122.494 140.955 135.363 1.00 133.05 ? 13  LYS H C   1 
ATOM   8943  O  O   . LYS D 4 13  ? 122.805 139.818 135.025 1.00 121.93 ? 13  LYS H O   1 
ATOM   8944  C  CB  . LYS D 4 13  ? 124.649 142.067 136.093 1.00 266.40 ? 13  LYS H CB  1 
ATOM   8945  C  CG  . LYS D 4 13  ? 125.358 142.938 137.125 1.00 315.74 ? 13  LYS H CG  1 
ATOM   8946  C  CD  . LYS D 4 13  ? 126.527 143.722 136.569 1.00 386.02 ? 13  LYS H CD  1 
ATOM   8947  C  CE  . LYS D 4 13  ? 127.628 142.837 136.019 1.00 477.01 ? 13  LYS H CE  1 
ATOM   8948  N  NZ  . LYS D 4 13  ? 128.786 143.624 135.532 1.00 515.15 ? 13  LYS H NZ  1 
ATOM   8949  N  N   . PRO D 4 14  ? 121.463 141.619 134.769 1.00 142.46 ? 14  PRO H N   1 
ATOM   8950  C  CA  . PRO D 4 14  ? 120.566 140.985 133.791 1.00 177.38 ? 14  PRO H CA  1 
ATOM   8951  C  C   . PRO D 4 14  ? 121.278 140.153 132.729 1.00 183.38 ? 14  PRO H C   1 
ATOM   8952  O  O   . PRO D 4 14  ? 122.312 140.558 132.208 1.00 240.05 ? 14  PRO H O   1 
ATOM   8953  C  CB  . PRO D 4 14  ? 119.796 142.139 133.126 1.00 189.37 ? 14  PRO H CB  1 
ATOM   8954  C  CG  . PRO D 4 14  ? 119.766 143.197 134.226 1.00 221.82 ? 14  PRO H CG  1 
ATOM   8955  C  CD  . PRO D 4 14  ? 121.046 143.012 135.034 1.00 204.17 ? 14  PRO H CD  1 
ATOM   8956  N  N   . GLY D 4 15  ? 120.705 138.978 132.450 1.00 184.71 ? 15  GLY H N   1 
ATOM   8957  C  CA  . GLY D 4 15  ? 121.242 138.023 131.495 1.00 196.08 ? 15  GLY H CA  1 
ATOM   8958  C  C   . GLY D 4 15  ? 122.222 137.014 132.109 1.00 197.20 ? 15  GLY H C   1 
ATOM   8959  O  O   . GLY D 4 15  ? 122.467 135.976 131.488 1.00 204.75 ? 15  GLY H O   1 
ATOM   8960  N  N   . ALA D 4 16  ? 122.793 137.295 133.298 1.00 160.89 ? 16  ALA H N   1 
ATOM   8961  C  CA  . ALA D 4 16  ? 123.787 136.394 133.884 1.00 189.98 ? 16  ALA H CA  1 
ATOM   8962  C  C   . ALA D 4 16  ? 123.111 135.177 134.531 1.00 178.96 ? 16  ALA H C   1 
ATOM   8963  O  O   . ALA D 4 16  ? 121.932 135.199 134.809 1.00 150.91 ? 16  ALA H O   1 
ATOM   8964  C  CB  . ALA D 4 16  ? 124.668 137.145 134.868 1.00 179.48 ? 16  ALA H CB  1 
ATOM   8965  N  N   . SER D 4 17  ? 123.872 134.107 134.777 1.00 229.93 ? 17  SER H N   1 
ATOM   8966  C  CA  . SER D 4 17  ? 123.383 132.980 135.557 1.00 264.28 ? 17  SER H CA  1 
ATOM   8967  C  C   . SER D 4 17  ? 123.537 133.252 137.054 1.00 222.08 ? 17  SER H C   1 
ATOM   8968  O  O   . SER D 4 17  ? 124.265 134.159 137.460 1.00 241.55 ? 17  SER H O   1 
ATOM   8969  C  CB  . SER D 4 17  ? 124.084 131.689 135.168 1.00 340.70 ? 17  SER H CB  1 
ATOM   8970  O  OG  . SER D 4 17  ? 125.462 131.703 135.529 1.00 324.41 ? 17  SER H OG  1 
ATOM   8971  N  N   . VAL D 4 18  ? 122.846 132.440 137.868 1.00 178.00 ? 18  VAL H N   1 
ATOM   8972  C  CA  . VAL D 4 18  ? 123.085 132.381 139.302 1.00 158.12 ? 18  VAL H CA  1 
ATOM   8973  C  C   . VAL D 4 18  ? 122.926 130.961 139.840 1.00 140.01 ? 18  VAL H C   1 
ATOM   8974  O  O   . VAL D 4 18  ? 122.136 130.187 139.289 1.00 184.32 ? 18  VAL H O   1 
ATOM   8975  C  CB  . VAL D 4 18  ? 122.124 133.337 140.012 1.00 154.77 ? 18  VAL H CB  1 
ATOM   8976  C  CG1 . VAL D 4 18  ? 120.677 132.924 139.842 1.00 131.97 ? 18  VAL H CG1 1 
ATOM   8977  C  CG2 . VAL D 4 18  ? 122.506 133.480 141.480 1.00 165.63 ? 18  VAL H CG2 1 
ATOM   8978  N  N   . ASN D 4 19  ? 123.687 130.649 140.901 1.00 125.03 ? 19  ASN H N   1 
ATOM   8979  C  CA  . ASN D 4 19  ? 123.516 129.428 141.673 1.00 168.41 ? 19  ASN H CA  1 
ATOM   8980  C  C   . ASN D 4 19  ? 122.859 129.756 143.009 1.00 166.24 ? 19  ASN H C   1 
ATOM   8981  O  O   . ASN D 4 19  ? 123.405 130.561 143.754 1.00 165.45 ? 19  ASN H O   1 
ATOM   8982  C  CB  . ASN D 4 19  ? 124.838 128.693 141.937 1.00 205.65 ? 19  ASN H CB  1 
ATOM   8983  C  CG  . ASN D 4 19  ? 125.325 127.886 140.745 1.00 224.90 ? 19  ASN H CG  1 
ATOM   8984  O  OD1 . ASN D 4 19  ? 125.427 128.447 139.652 1.00 207.64 ? 19  ASN H OD1 1 
ATOM   8985  N  ND2 . ASN D 4 19  ? 125.619 126.596 140.927 1.00 204.77 ? 19  ASN H ND2 1 
ATOM   8986  N  N   . LEU D 4 20  ? 121.703 129.119 143.281 1.00 138.17 ? 20  LEU H N   1 
ATOM   8987  C  CA  . LEU D 4 20  ? 120.990 129.183 144.551 1.00 106.35 ? 20  LEU H CA  1 
ATOM   8988  C  C   . LEU D 4 20  ? 121.160 127.822 145.198 1.00 104.66 ? 20  LEU H C   1 
ATOM   8989  O  O   . LEU D 4 20  ? 121.074 126.799 144.509 1.00 143.93 ? 20  LEU H O   1 
ATOM   8990  C  CB  . LEU D 4 20  ? 119.523 129.491 144.262 1.00 104.97 ? 20  LEU H CB  1 
ATOM   8991  C  CG  . LEU D 4 20  ? 119.268 130.530 143.158 1.00 137.83 ? 20  LEU H CG  1 
ATOM   8992  C  CD1 . LEU D 4 20  ? 117.791 130.688 142.759 1.00 114.62 ? 20  LEU H CD1 1 
ATOM   8993  C  CD2 . LEU D 4 20  ? 119.807 131.860 143.629 1.00 212.33 ? 20  LEU H CD2 1 
ATOM   8994  N  N   . SER D 4 21  ? 121.422 127.769 146.499 1.00 105.59 ? 21  SER H N   1 
ATOM   8995  C  CA  . SER D 4 21  ? 121.965 126.541 147.093 1.00 144.72 ? 21  SER H CA  1 
ATOM   8996  C  C   . SER D 4 21  ? 121.268 126.219 148.414 1.00 109.39 ? 21  SER H C   1 
ATOM   8997  O  O   . SER D 4 21  ? 120.923 127.124 149.158 1.00 150.88 ? 21  SER H O   1 
ATOM   8998  C  CB  . SER D 4 21  ? 123.479 126.623 147.260 1.00 196.88 ? 21  SER H CB  1 
ATOM   8999  O  OG  . SER D 4 21  ? 123.839 127.740 148.070 1.00 250.32 ? 21  SER H OG  1 
ATOM   9000  N  N   . CYS D 4 22  ? 121.068 124.938 148.694 1.00 105.39 ? 22  CYS H N   1 
ATOM   9001  C  CA  . CYS D 4 22  ? 120.135 124.505 149.720 1.00 126.78 ? 22  CYS H CA  1 
ATOM   9002  C  C   . CYS D 4 22  ? 120.696 123.276 150.416 1.00 118.30 ? 22  CYS H C   1 
ATOM   9003  O  O   . CYS D 4 22  ? 120.805 122.218 149.816 1.00 146.70 ? 22  CYS H O   1 
ATOM   9004  C  CB  . CYS D 4 22  ? 118.767 124.159 149.130 1.00 164.62 ? 22  CYS H CB  1 
ATOM   9005  S  SG  . CYS D 4 22  ? 117.576 123.466 150.316 1.00 128.57 ? 22  CYS H SG  1 
ATOM   9006  N  N   . LYS D 4 23  ? 121.050 123.426 151.682 1.00 137.37 ? 23  LYS H N   1 
ATOM   9007  C  CA  . LYS D 4 23  ? 121.638 122.338 152.423 1.00 150.89 ? 23  LYS H CA  1 
ATOM   9008  C  C   . LYS D 4 23  ? 120.570 121.731 153.331 1.00 125.42 ? 23  LYS H C   1 
ATOM   9009  O  O   . LYS D 4 23  ? 120.001 122.427 154.185 1.00 105.83 ? 23  LYS H O   1 
ATOM   9010  C  CB  . LYS D 4 23  ? 122.840 122.863 153.212 1.00 220.06 ? 23  LYS H CB  1 
ATOM   9011  C  CG  . LYS D 4 23  ? 123.739 121.784 153.783 1.00 239.67 ? 23  LYS H CG  1 
ATOM   9012  C  CD  . LYS D 4 23  ? 125.065 122.310 154.268 1.00 246.01 ? 23  LYS H CD  1 
ATOM   9013  C  CE  . LYS D 4 23  ? 125.965 121.203 154.779 1.00 306.92 ? 23  LYS H CE  1 
ATOM   9014  N  NZ  . LYS D 4 23  ? 125.324 120.354 155.819 1.00 305.61 ? 23  LYS H NZ  1 
ATOM   9015  N  N   . ALA D 4 24  ? 120.360 120.433 153.126 1.00 115.29 ? 24  ALA H N   1 
ATOM   9016  C  CA  . ALA D 4 24  ? 119.487 119.632 153.951 1.00 116.82 ? 24  ALA H CA  1 
ATOM   9017  C  C   . ALA D 4 24  ? 120.187 119.168 155.221 1.00 114.81 ? 24  ALA H C   1 
ATOM   9018  O  O   . ALA D 4 24  ? 121.408 119.025 155.288 1.00 163.27 ? 24  ALA H O   1 
ATOM   9019  C  CB  . ALA D 4 24  ? 119.017 118.421 153.155 1.00 125.37 ? 24  ALA H CB  1 
ATOM   9020  N  N   . SER D 4 25  ? 119.363 118.878 156.221 1.00 146.06 ? 25  SER H N   1 
ATOM   9021  C  CA  . SER D 4 25  ? 119.801 118.220 157.435 1.00 179.75 ? 25  SER H CA  1 
ATOM   9022  C  C   . SER D 4 25  ? 118.637 117.468 158.073 1.00 118.92 ? 25  SER H C   1 
ATOM   9023  O  O   . SER D 4 25  ? 117.474 117.783 157.842 1.00 142.74 ? 25  SER H O   1 
ATOM   9024  C  CB  . SER D 4 25  ? 120.388 119.220 158.370 1.00 216.21 ? 25  SER H CB  1 
ATOM   9025  O  OG  . SER D 4 25  ? 119.423 120.198 158.698 1.00 245.65 ? 25  SER H OG  1 
ATOM   9026  N  N   . GLY D 4 26  ? 118.993 116.460 158.855 1.00 139.19 ? 26  GLY H N   1 
ATOM   9027  C  CA  . GLY D 4 26  ? 118.051 115.768 159.717 1.00 190.42 ? 26  GLY H CA  1 
ATOM   9028  C  C   . GLY D 4 26  ? 117.380 114.559 159.075 1.00 178.62 ? 26  GLY H C   1 
ATOM   9029  O  O   . GLY D 4 26  ? 116.439 114.024 159.679 1.00 162.69 ? 26  GLY H O   1 
ATOM   9030  N  N   . TYR D 4 27  ? 117.842 114.149 157.875 1.00 163.16 ? 27  TYR H N   1 
ATOM   9031  C  CA  . TYR D 4 27  ? 117.274 112.972 157.213 1.00 182.87 ? 27  TYR H CA  1 
ATOM   9032  C  C   . TYR D 4 27  ? 118.273 112.410 156.194 1.00 199.84 ? 27  TYR H C   1 
ATOM   9033  O  O   . TYR D 4 27  ? 119.229 113.112 155.805 1.00 137.19 ? 27  TYR H O   1 
ATOM   9034  C  CB  . TYR D 4 27  ? 115.911 113.251 156.536 1.00 166.55 ? 27  TYR H CB  1 
ATOM   9035  C  CG  . TYR D 4 27  ? 115.982 114.195 155.337 1.00 156.89 ? 27  TYR H CG  1 
ATOM   9036  C  CD1 . TYR D 4 27  ? 115.917 115.577 155.473 1.00 171.14 ? 27  TYR H CD1 1 
ATOM   9037  C  CD2 . TYR D 4 27  ? 116.157 113.682 154.051 1.00 179.74 ? 27  TYR H CD2 1 
ATOM   9038  C  CE1 . TYR D 4 27  ? 116.001 116.400 154.364 1.00 155.94 ? 27  TYR H CE1 1 
ATOM   9039  C  CE2 . TYR D 4 27  ? 116.248 114.495 152.941 1.00 141.83 ? 27  TYR H CE2 1 
ATOM   9040  C  CZ  . TYR D 4 27  ? 116.175 115.853 153.109 1.00 124.63 ? 27  TYR H CZ  1 
ATOM   9041  O  OH  . TYR D 4 27  ? 116.262 116.645 152.029 1.00 117.13 ? 27  TYR H OH  1 
ATOM   9042  N  N   . THR D 4 28  ? 117.995 111.146 155.786 1.00 180.94 ? 28  THR H N   1 
ATOM   9043  C  CA  . THR D 4 28  ? 118.767 110.415 154.791 1.00 160.97 ? 28  THR H CA  1 
ATOM   9044  C  C   . THR D 4 28  ? 118.600 111.035 153.408 1.00 139.81 ? 28  THR H C   1 
ATOM   9045  O  O   . THR D 4 28  ? 117.580 110.821 152.781 1.00 239.28 ? 28  THR H O   1 
ATOM   9046  C  CB  . THR D 4 28  ? 118.326 108.951 154.679 1.00 188.64 ? 28  THR H CB  1 
ATOM   9047  O  OG1 . THR D 4 28  ? 118.265 108.314 155.968 1.00 253.81 ? 28  THR H OG1 1 
ATOM   9048  C  CG2 . THR D 4 28  ? 119.234 108.197 153.712 1.00 233.30 ? 28  THR H CG2 1 
ATOM   9049  N  N   . PHE D 4 29  ? 119.567 111.794 152.902 1.00 143.11 ? 29  PHE H N   1 
ATOM   9050  C  CA  . PHE D 4 29  ? 119.302 112.753 151.827 1.00 124.73 ? 29  PHE H CA  1 
ATOM   9051  C  C   . PHE D 4 29  ? 118.816 112.134 150.522 1.00 125.39 ? 29  PHE H C   1 
ATOM   9052  O  O   . PHE D 4 29  ? 118.008 112.745 149.855 1.00 148.91 ? 29  PHE H O   1 
ATOM   9053  C  CB  . PHE D 4 29  ? 120.577 113.474 151.486 1.00 141.96 ? 29  PHE H CB  1 
ATOM   9054  C  CG  . PHE D 4 29  ? 120.452 114.580 150.495 1.00 103.37 ? 29  PHE H CG  1 
ATOM   9055  C  CD1 . PHE D 4 29  ? 119.568 115.613 150.694 1.00 80.43  ? 29  PHE H CD1 1 
ATOM   9056  C  CD2 . PHE D 4 29  ? 121.297 114.601 149.385 1.00 128.90 ? 29  PHE H CD2 1 
ATOM   9057  C  CE1 . PHE D 4 29  ? 119.561 116.652 149.753 1.00 143.44 ? 29  PHE H CE1 1 
ATOM   9058  C  CE2 . PHE D 4 29  ? 121.269 115.641 148.460 1.00 92.66  ? 29  PHE H CE2 1 
ATOM   9059  C  CZ  . PHE D 4 29  ? 120.402 116.679 148.632 1.00 93.84  ? 29  PHE H CZ  1 
ATOM   9060  N  N   . THR D 4 30  ? 119.263 110.919 150.190 1.00 138.38 ? 30  THR H N   1 
ATOM   9061  C  CA  . THR D 4 30  ? 118.875 110.254 148.959 1.00 139.95 ? 30  THR H CA  1 
ATOM   9062  C  C   . THR D 4 30  ? 117.436 109.710 148.952 1.00 149.56 ? 30  THR H C   1 
ATOM   9063  O  O   . THR D 4 30  ? 116.954 109.341 147.886 1.00 188.81 ? 30  THR H O   1 
ATOM   9064  C  CB  . THR D 4 30  ? 119.863 109.123 148.675 1.00 184.59 ? 30  THR H CB  1 
ATOM   9065  O  OG1 . THR D 4 30  ? 119.794 108.149 149.731 1.00 169.38 ? 30  THR H OG1 1 
ATOM   9066  C  CG2 . THR D 4 30  ? 121.271 109.656 148.511 1.00 220.87 ? 30  THR H CG2 1 
ATOM   9067  N  N   . ASN D 4 31  ? 116.727 109.647 150.088 1.00 112.25 ? 31  ASN H N   1 
ATOM   9068  C  CA  . ASN D 4 31  ? 115.416 109.031 150.130 1.00 124.65 ? 31  ASN H CA  1 
ATOM   9069  C  C   . ASN D 4 31  ? 114.347 109.953 149.568 1.00 108.53 ? 31  ASN H C   1 
ATOM   9070  O  O   . ASN D 4 31  ? 113.263 109.453 149.256 1.00 180.14 ? 31  ASN H O   1 
ATOM   9071  C  CB  . ASN D 4 31  ? 114.956 108.682 151.551 1.00 172.25 ? 31  ASN H CB  1 
ATOM   9072  C  CG  . ASN D 4 31  ? 115.419 107.342 152.073 1.00 208.19 ? 31  ASN H CG  1 
ATOM   9073  O  OD1 . ASN D 4 31  ? 116.062 106.568 151.363 1.00 213.39 ? 31  ASN H OD1 1 
ATOM   9074  N  ND2 . ASN D 4 31  ? 115.068 107.060 153.323 1.00 213.15 ? 31  ASN H ND2 1 
ATOM   9075  N  N   . TYR D 4 32  ? 114.602 111.261 149.452 1.00 79.29  ? 32  TYR H N   1 
ATOM   9076  C  CA  . TYR D 4 32  ? 113.514 112.183 149.142 1.00 103.34 ? 32  TYR H CA  1 
ATOM   9077  C  C   . TYR D 4 32  ? 113.847 113.254 148.124 1.00 98.77  ? 32  TYR H C   1 
ATOM   9078  O  O   . TYR D 4 32  ? 114.960 113.826 148.159 1.00 94.75  ? 32  TYR H O   1 
ATOM   9079  C  CB  . TYR D 4 32  ? 113.191 112.936 150.408 1.00 91.70  ? 32  TYR H CB  1 
ATOM   9080  C  CG  . TYR D 4 32  ? 112.692 112.026 151.501 1.00 96.37  ? 32  TYR H CG  1 
ATOM   9081  C  CD1 . TYR D 4 32  ? 111.378 111.608 151.552 1.00 127.14 ? 32  TYR H CD1 1 
ATOM   9082  C  CD2 . TYR D 4 32  ? 113.534 111.611 152.483 1.00 113.91 ? 32  TYR H CD2 1 
ATOM   9083  C  CE1 . TYR D 4 32  ? 110.910 110.790 152.558 1.00 131.79 ? 32  TYR H CE1 1 
ATOM   9084  C  CE2 . TYR D 4 32  ? 113.081 110.799 153.507 1.00 173.27 ? 32  TYR H CE2 1 
ATOM   9085  C  CZ  . TYR D 4 32  ? 111.766 110.382 153.544 1.00 147.52 ? 32  TYR H CZ  1 
ATOM   9086  O  OH  . TYR D 4 32  ? 111.295 109.576 154.537 1.00 259.64 ? 32  TYR H OH  1 
ATOM   9087  N  N   . TRP D 4 33  ? 112.887 113.512 147.231 1.00 72.75  ? 33  TRP H N   1 
ATOM   9088  C  CA  . TRP D 4 33  ? 113.297 114.372 146.147 1.00 83.12  ? 33  TRP H CA  1 
ATOM   9089  C  C   . TRP D 4 33  ? 113.204 115.800 146.622 1.00 72.44  ? 33  TRP H C   1 
ATOM   9090  O  O   . TRP D 4 33  ? 112.397 116.042 147.513 1.00 72.29  ? 33  TRP H O   1 
ATOM   9091  C  CB  . TRP D 4 33  ? 112.431 114.253 144.917 1.00 101.58 ? 33  TRP H CB  1 
ATOM   9092  C  CG  . TRP D 4 33  ? 112.459 113.000 144.129 1.00 77.56  ? 33  TRP H CG  1 
ATOM   9093  C  CD1 . TRP D 4 33  ? 112.523 111.739 144.584 1.00 62.49  ? 33  TRP H CD1 1 
ATOM   9094  C  CD2 . TRP D 4 33  ? 112.328 112.959 142.696 1.00 71.14  ? 33  TRP H CD2 1 
ATOM   9095  N  NE1 . TRP D 4 33  ? 112.480 110.920 143.502 1.00 79.07  ? 33  TRP H NE1 1 
ATOM   9096  C  CE2 . TRP D 4 33  ? 112.352 111.628 142.329 1.00 69.26  ? 33  TRP H CE2 1 
ATOM   9097  C  CE3 . TRP D 4 33  ? 112.190 113.908 141.702 1.00 76.80  ? 33  TRP H CE3 1 
ATOM   9098  C  CZ2 . TRP D 4 33  ? 112.241 111.196 141.010 1.00 72.73  ? 33  TRP H CZ2 1 
ATOM   9099  C  CZ3 . TRP D 4 33  ? 112.088 113.487 140.412 1.00 106.65 ? 33  TRP H CZ3 1 
ATOM   9100  C  CH2 . TRP D 4 33  ? 112.089 112.148 140.063 1.00 78.29  ? 33  TRP H CH2 1 
ATOM   9101  N  N   . MET D 4 34  ? 113.959 116.683 145.964 1.00 67.51  ? 34  MET H N   1 
ATOM   9102  C  CA  . MET D 4 34  ? 114.040 118.066 146.350 1.00 72.83  ? 34  MET H CA  1 
ATOM   9103  C  C   . MET D 4 34  ? 113.387 118.957 145.315 1.00 68.97  ? 34  MET H C   1 
ATOM   9104  O  O   . MET D 4 34  ? 113.670 118.860 144.144 1.00 77.55  ? 34  MET H O   1 
ATOM   9105  C  CB  . MET D 4 34  ? 115.517 118.426 146.501 1.00 68.73  ? 34  MET H CB  1 
ATOM   9106  C  CG  . MET D 4 34  ? 115.704 119.738 147.167 1.00 72.75  ? 34  MET H CG  1 
ATOM   9107  S  SD  . MET D 4 34  ? 115.189 119.432 148.886 1.00 118.82 ? 34  MET H SD  1 
ATOM   9108  C  CE  . MET D 4 34  ? 116.604 118.449 149.365 1.00 124.90 ? 34  MET H CE  1 
ATOM   9109  N  N   . HIS D 4 35  ? 112.496 119.820 145.751 1.00 65.84  ? 35  HIS H N   1 
ATOM   9110  C  CA  . HIS D 4 35  ? 111.747 120.658 144.851 1.00 68.04  ? 35  HIS H CA  1 
ATOM   9111  C  C   . HIS D 4 35  ? 112.178 122.129 145.021 1.00 71.50  ? 35  HIS H C   1 
ATOM   9112  O  O   . HIS D 4 35  ? 112.497 122.607 146.102 1.00 84.11  ? 35  HIS H O   1 
ATOM   9113  C  CB  . HIS D 4 35  ? 110.286 120.615 145.232 1.00 71.04  ? 35  HIS H CB  1 
ATOM   9114  C  CG  . HIS D 4 35  ? 109.650 119.373 145.198 1.00 63.48  ? 35  HIS H CG  1 
ATOM   9115  N  ND1 . HIS D 4 35  ? 108.790 119.091 144.184 1.00 57.76  ? 35  HIS H ND1 1 
ATOM   9116  C  CD2 . HIS D 4 35  ? 109.713 118.314 146.044 1.00 80.48  ? 35  HIS H CD2 1 
ATOM   9117  C  CE1 . HIS D 4 35  ? 108.311 117.830 144.437 1.00 94.94  ? 35  HIS H CE1 1 
ATOM   9118  N  NE2 . HIS D 4 35  ? 108.857 117.328 145.542 1.00 84.77  ? 35  HIS H NE2 1 
ATOM   9119  N  N   . TRP D 4 36  ? 112.130 122.871 143.931 1.00 82.85  ? 36  TRP H N   1 
ATOM   9120  C  CA  . TRP D 4 36  ? 112.345 124.310 143.887 1.00 77.23  ? 36  TRP H CA  1 
ATOM   9121  C  C   . TRP D 4 36  ? 111.064 125.046 143.525 1.00 80.91  ? 36  TRP H C   1 
ATOM   9122  O  O   . TRP D 4 36  ? 110.476 124.781 142.493 1.00 105.93 ? 36  TRP H O   1 
ATOM   9123  C  CB  . TRP D 4 36  ? 113.461 124.579 142.864 1.00 87.13  ? 36  TRP H CB  1 
ATOM   9124  C  CG  . TRP D 4 36  ? 114.759 124.123 143.478 1.00 97.60  ? 36  TRP H CG  1 
ATOM   9125  C  CD1 . TRP D 4 36  ? 115.300 122.885 143.405 1.00 140.37 ? 36  TRP H CD1 1 
ATOM   9126  C  CD2 . TRP D 4 36  ? 115.637 124.870 144.325 1.00 84.95  ? 36  TRP H CD2 1 
ATOM   9127  N  NE1 . TRP D 4 36  ? 116.455 122.817 144.124 1.00 135.50 ? 36  TRP H NE1 1 
ATOM   9128  C  CE2 . TRP D 4 36  ? 116.687 124.022 144.704 1.00 110.37 ? 36  TRP H CE2 1 
ATOM   9129  C  CE3 . TRP D 4 36  ? 115.613 126.167 144.791 1.00 80.52  ? 36  TRP H CE3 1 
ATOM   9130  C  CZ2 . TRP D 4 36  ? 117.722 124.420 145.531 1.00 110.75 ? 36  TRP H CZ2 1 
ATOM   9131  C  CZ3 . TRP D 4 36  ? 116.629 126.574 145.602 1.00 141.00 ? 36  TRP H CZ3 1 
ATOM   9132  C  CH2 . TRP D 4 36  ? 117.665 125.712 145.974 1.00 156.90 ? 36  TRP H CH2 1 
ATOM   9133  N  N   . VAL D 4 37  ? 110.599 125.956 144.361 1.00 69.06  ? 37  VAL H N   1 
ATOM   9134  C  CA  . VAL D 4 37  ? 109.406 126.743 144.080 1.00 61.06  ? 37  VAL H CA  1 
ATOM   9135  C  C   . VAL D 4 37  ? 109.807 128.207 144.176 1.00 74.10  ? 37  VAL H C   1 
ATOM   9136  O  O   . VAL D 4 37  ? 110.765 128.589 144.836 1.00 88.25  ? 37  VAL H O   1 
ATOM   9137  C  CB  . VAL D 4 37  ? 108.354 126.383 145.148 1.00 81.29  ? 37  VAL H CB  1 
ATOM   9138  C  CG1 . VAL D 4 37  ? 107.120 127.287 145.253 1.00 74.60  ? 37  VAL H CG1 1 
ATOM   9139  C  CG2 . VAL D 4 37  ? 107.888 124.963 144.991 1.00 100.84 ? 37  VAL H CG2 1 
ATOM   9140  N  N   . ARG D 4 38  ? 109.054 129.070 143.532 1.00 81.40  ? 38  ARG H N   1 
ATOM   9141  C  CA  . ARG D 4 38  ? 109.362 130.487 143.407 1.00 81.19  ? 38  ARG H CA  1 
ATOM   9142  C  C   . ARG D 4 38  ? 108.136 131.310 143.822 1.00 108.15 ? 38  ARG H C   1 
ATOM   9143  O  O   . ARG D 4 38  ? 106.999 130.867 143.717 1.00 126.00 ? 38  ARG H O   1 
ATOM   9144  C  CB  . ARG D 4 38  ? 109.600 130.602 141.919 1.00 84.13  ? 38  ARG H CB  1 
ATOM   9145  C  CG  . ARG D 4 38  ? 109.838 131.976 141.341 1.00 95.91  ? 38  ARG H CG  1 
ATOM   9146  C  CD  . ARG D 4 38  ? 109.432 132.136 139.884 1.00 110.16 ? 38  ARG H CD  1 
ATOM   9147  N  NE  . ARG D 4 38  ? 110.516 132.603 139.050 1.00 80.95  ? 38  ARG H NE  1 
ATOM   9148  C  CZ  . ARG D 4 38  ? 110.367 132.968 137.795 1.00 115.16 ? 38  ARG H CZ  1 
ATOM   9149  N  NH1 . ARG D 4 38  ? 111.435 133.413 137.155 1.00 160.80 ? 38  ARG H NH1 1 
ATOM   9150  N  NH2 . ARG D 4 38  ? 109.180 132.904 137.193 1.00 119.61 ? 38  ARG H NH2 1 
ATOM   9151  N  N   . LEU D 4 39  ? 108.339 132.528 144.284 1.00 118.21 ? 39  LEU H N   1 
ATOM   9152  C  CA  . LEU D 4 39  ? 107.234 133.412 144.619 1.00 105.43 ? 39  LEU H CA  1 
ATOM   9153  C  C   . LEU D 4 39  ? 107.518 134.837 144.073 1.00 134.81 ? 39  LEU H C   1 
ATOM   9154  O  O   . LEU D 4 39  ? 108.160 135.693 144.706 1.00 108.48 ? 39  LEU H O   1 
ATOM   9155  C  CB  . LEU D 4 39  ? 107.118 133.322 146.139 1.00 95.49  ? 39  LEU H CB  1 
ATOM   9156  C  CG  . LEU D 4 39  ? 106.155 134.334 146.725 1.00 140.34 ? 39  LEU H CG  1 
ATOM   9157  C  CD1 . LEU D 4 39  ? 104.741 134.044 146.174 1.00 200.40 ? 39  LEU H CD1 1 
ATOM   9158  C  CD2 . LEU D 4 39  ? 106.282 134.362 148.238 1.00 160.96 ? 39  LEU H CD2 1 
ATOM   9159  N  N   . ARG D 4 40  ? 107.053 135.081 142.832 1.00 152.20 ? 40  ARG H N   1 
ATOM   9160  C  CA  . ARG D 4 40  ? 107.046 136.404 142.228 1.00 140.26 ? 40  ARG H CA  1 
ATOM   9161  C  C   . ARG D 4 40  ? 106.232 137.301 143.157 1.00 136.04 ? 40  ARG H C   1 
ATOM   9162  O  O   . ARG D 4 40  ? 105.174 136.869 143.619 1.00 217.24 ? 40  ARG H O   1 
ATOM   9163  C  CB  . ARG D 4 40  ? 106.401 136.350 140.826 1.00 214.46 ? 40  ARG H CB  1 
ATOM   9164  C  CG  . ARG D 4 40  ? 107.159 135.635 139.696 1.00 168.37 ? 40  ARG H CG  1 
ATOM   9165  C  CD  . ARG D 4 40  ? 108.466 136.301 139.322 1.00 187.29 ? 40  ARG H CD  1 
ATOM   9166  N  NE  . ARG D 4 40  ? 108.529 137.760 139.507 1.00 253.29 ? 40  ARG H NE  1 
ATOM   9167  C  CZ  . ARG D 4 40  ? 107.830 138.674 138.821 1.00 323.80 ? 40  ARG H CZ  1 
ATOM   9168  N  NH1 . ARG D 4 40  ? 107.938 139.964 139.110 1.00 343.68 ? 40  ARG H NH1 1 
ATOM   9169  N  NH2 . ARG D 4 40  ? 107.011 138.300 137.852 1.00 325.68 ? 40  ARG H NH2 1 
ATOM   9170  N  N   . PRO D 4 41  ? 106.637 138.543 143.486 1.00 178.01 ? 41  PRO H N   1 
ATOM   9171  C  CA  . PRO D 4 41  ? 105.803 139.416 144.324 1.00 195.79 ? 41  PRO H CA  1 
ATOM   9172  C  C   . PRO D 4 41  ? 104.397 139.690 143.773 1.00 215.66 ? 41  PRO H C   1 
ATOM   9173  O  O   . PRO D 4 41  ? 104.220 139.991 142.587 1.00 187.48 ? 41  PRO H O   1 
ATOM   9174  C  CB  . PRO D 4 41  ? 106.618 140.712 144.384 1.00 259.96 ? 41  PRO H CB  1 
ATOM   9175  C  CG  . PRO D 4 41  ? 108.039 140.247 144.163 1.00 290.85 ? 41  PRO H CG  1 
ATOM   9176  C  CD  . PRO D 4 41  ? 107.909 139.169 143.106 1.00 265.83 ? 41  PRO H CD  1 
ATOM   9177  N  N   . GLY D 4 42  ? 103.402 139.555 144.665 1.00 263.96 ? 42  GLY H N   1 
ATOM   9178  C  CA  . GLY D 4 42  ? 102.001 139.842 144.387 1.00 303.88 ? 42  GLY H CA  1 
ATOM   9179  C  C   . GLY D 4 42  ? 101.341 138.950 143.334 1.00 244.15 ? 42  GLY H C   1 
ATOM   9180  O  O   . GLY D 4 42  ? 100.331 139.352 142.772 1.00 290.36 ? 42  GLY H O   1 
ATOM   9181  N  N   . GLN D 4 43  ? 101.893 137.760 143.075 1.00 210.74 ? 43  GLN H N   1 
ATOM   9182  C  CA  . GLN D 4 43  ? 101.548 136.973 141.894 1.00 225.71 ? 43  GLN H CA  1 
ATOM   9183  C  C   . GLN D 4 43  ? 101.429 135.464 142.199 1.00 235.02 ? 43  GLN H C   1 
ATOM   9184  O  O   . GLN D 4 43  ? 101.156 134.676 141.288 1.00 223.16 ? 43  GLN H O   1 
ATOM   9185  C  CB  . GLN D 4 43  ? 102.578 137.352 140.815 1.00 189.02 ? 43  GLN H CB  1 
ATOM   9186  C  CG  . GLN D 4 43  ? 102.517 136.545 139.520 1.00 207.84 ? 43  GLN H CG  1 
ATOM   9187  C  CD  . GLN D 4 43  ? 103.434 137.026 138.422 1.00 279.95 ? 43  GLN H CD  1 
ATOM   9188  O  OE1 . GLN D 4 43  ? 103.844 138.184 138.389 1.00 340.77 ? 43  GLN H OE1 1 
ATOM   9189  N  NE2 . GLN D 4 43  ? 103.759 136.133 137.495 1.00 286.60 ? 43  GLN H NE2 1 
ATOM   9190  N  N   . GLY D 4 44  ? 101.612 135.028 143.456 1.00 196.63 ? 44  GLY H N   1 
ATOM   9191  C  CA  . GLY D 4 44  ? 101.359 133.640 143.818 1.00 205.65 ? 44  GLY H CA  1 
ATOM   9192  C  C   . GLY D 4 44  ? 102.509 132.693 143.478 1.00 171.40 ? 44  GLY H C   1 
ATOM   9193  O  O   . GLY D 4 44  ? 103.308 132.958 142.583 1.00 156.26 ? 44  GLY H O   1 
ATOM   9194  N  N   . LEU D 4 45  ? 102.568 131.576 144.216 1.00 132.56 ? 45  LEU H N   1 
ATOM   9195  C  CA  . LEU D 4 45  ? 103.667 130.625 144.108 1.00 112.24 ? 45  LEU H CA  1 
ATOM   9196  C  C   . LEU D 4 45  ? 103.706 129.949 142.731 1.00 110.93 ? 45  LEU H C   1 
ATOM   9197  O  O   . LEU D 4 45  ? 102.668 129.819 142.086 1.00 177.27 ? 45  LEU H O   1 
ATOM   9198  C  CB  . LEU D 4 45  ? 103.448 129.548 145.163 1.00 100.98 ? 45  LEU H CB  1 
ATOM   9199  C  CG  . LEU D 4 45  ? 103.562 129.970 146.605 1.00 93.10  ? 45  LEU H CG  1 
ATOM   9200  C  CD1 . LEU D 4 45  ? 102.927 128.919 147.457 1.00 97.11  ? 45  LEU H CD1 1 
ATOM   9201  C  CD2 . LEU D 4 45  ? 105.025 130.095 146.945 1.00 103.00 ? 45  LEU H CD2 1 
ATOM   9202  N  N   . GLU D 4 46  ? 104.899 129.528 142.287 1.00 104.97 ? 46  GLU H N   1 
ATOM   9203  C  CA  . GLU D 4 46  ? 105.114 128.819 141.024 1.00 112.87 ? 46  GLU H CA  1 
ATOM   9204  C  C   . GLU D 4 46  ? 106.213 127.785 141.203 1.00 111.16 ? 46  GLU H C   1 
ATOM   9205  O  O   . GLU D 4 46  ? 107.235 128.079 141.804 1.00 82.64  ? 46  GLU H O   1 
ATOM   9206  C  CB  . GLU D 4 46  ? 105.560 129.824 139.957 1.00 146.58 ? 46  GLU H CB  1 
ATOM   9207  C  CG  . GLU D 4 46  ? 105.764 129.237 138.568 1.00 191.53 ? 46  GLU H CG  1 
ATOM   9208  C  CD  . GLU D 4 46  ? 106.026 130.312 137.512 1.00 310.63 ? 46  GLU H CD  1 
ATOM   9209  O  OE1 . GLU D 4 46  ? 106.667 131.370 137.839 1.00 282.13 ? 46  GLU H OE1 1 
ATOM   9210  O  OE2 . GLU D 4 46  ? 105.590 130.097 136.350 1.00 391.59 ? 46  GLU H OE2 1 
ATOM   9211  N  N   . TRP D 4 47  ? 106.048 126.573 140.680 1.00 108.70 ? 47  TRP H N   1 
ATOM   9212  C  CA  . TRP D 4 47  ? 106.988 125.493 140.976 1.00 78.88  ? 47  TRP H CA  1 
ATOM   9213  C  C   . TRP D 4 47  ? 107.906 125.289 139.801 1.00 80.71  ? 47  TRP H C   1 
ATOM   9214  O  O   . TRP D 4 47  ? 107.458 125.284 138.633 1.00 111.84 ? 47  TRP H O   1 
ATOM   9215  C  CB  . TRP D 4 47  ? 106.141 124.258 141.215 1.00 81.88  ? 47  TRP H CB  1 
ATOM   9216  C  CG  . TRP D 4 47  ? 106.756 122.909 141.445 1.00 84.06  ? 47  TRP H CG  1 
ATOM   9217  C  CD1 . TRP D 4 47  ? 106.941 122.359 142.676 1.00 86.41  ? 47  TRP H CD1 1 
ATOM   9218  C  CD2 . TRP D 4 47  ? 107.151 121.890 140.506 1.00 67.16  ? 47  TRP H CD2 1 
ATOM   9219  N  NE1 . TRP D 4 47  ? 107.485 121.112 142.578 1.00 58.66  ? 47  TRP H NE1 1 
ATOM   9220  C  CE2 . TRP D 4 47  ? 107.604 120.797 141.261 1.00 66.59  ? 47  TRP H CE2 1 
ATOM   9221  C  CE3 . TRP D 4 47  ? 107.195 121.798 139.127 1.00 63.34  ? 47  TRP H CE3 1 
ATOM   9222  C  CZ2 . TRP D 4 47  ? 108.059 119.643 140.652 1.00 78.88  ? 47  TRP H CZ2 1 
ATOM   9223  C  CZ3 . TRP D 4 47  ? 107.639 120.636 138.533 1.00 68.21  ? 47  TRP H CZ3 1 
ATOM   9224  C  CH2 . TRP D 4 47  ? 108.035 119.555 139.279 1.00 66.18  ? 47  TRP H CH2 1 
ATOM   9225  N  N   . ILE D 4 48  ? 109.189 125.155 140.122 1.00 68.15  ? 48  ILE H N   1 
ATOM   9226  C  CA  . ILE D 4 48  ? 110.201 125.105 139.084 1.00 94.69  ? 48  ILE H CA  1 
ATOM   9227  C  C   . ILE D 4 48  ? 110.377 123.652 138.609 1.00 88.52  ? 48  ILE H C   1 
ATOM   9228  O  O   . ILE D 4 48  ? 110.307 123.269 137.448 1.00 50.22  ? 48  ILE H O   1 
ATOM   9229  C  CB  . ILE D 4 48  ? 111.499 125.734 139.611 1.00 69.19  ? 48  ILE H CB  1 
ATOM   9230  C  CG1 . ILE D 4 48  ? 111.254 127.184 139.901 1.00 65.66  ? 48  ILE H CG1 1 
ATOM   9231  C  CG2 . ILE D 4 48  ? 112.606 125.620 138.633 1.00 83.19  ? 48  ILE H CG2 1 
ATOM   9232  C  CD1 . ILE D 4 48  ? 112.477 127.807 140.427 1.00 117.32 ? 48  ILE H CD1 1 
ATOM   9233  N  N   . GLY D 4 49  ? 110.662 122.810 139.552 1.00 79.34  ? 49  GLY H N   1 
ATOM   9234  C  CA  . GLY D 4 49  ? 111.098 121.491 139.205 1.00 71.68  ? 49  GLY H CA  1 
ATOM   9235  C  C   . GLY D 4 49  ? 111.698 120.799 140.436 1.00 82.50  ? 49  GLY H C   1 
ATOM   9236  O  O   . GLY D 4 49  ? 111.875 121.376 141.502 1.00 104.28 ? 49  GLY H O   1 
ATOM   9237  N  N   . GLU D 4 50  ? 112.036 119.549 140.222 1.00 72.87  ? 50  GLU H N   1 
ATOM   9238  C  CA  . GLU D 4 50  ? 112.567 118.749 141.263 1.00 54.28  ? 50  GLU H CA  1 
ATOM   9239  C  C   . GLU D 4 50  ? 113.633 117.798 140.744 1.00 59.65  ? 50  GLU H C   1 
ATOM   9240  O  O   . GLU D 4 50  ? 113.768 117.528 139.554 1.00 61.46  ? 50  GLU H O   1 
ATOM   9241  C  CB  . GLU D 4 50  ? 111.406 117.960 141.753 1.00 67.32  ? 50  GLU H CB  1 
ATOM   9242  C  CG  . GLU D 4 50  ? 110.764 117.035 140.741 1.00 68.81  ? 50  GLU H CG  1 
ATOM   9243  C  CD  . GLU D 4 50  ? 109.734 116.062 141.336 1.00 83.47  ? 50  GLU H CD  1 
ATOM   9244  O  OE1 . GLU D 4 50  ? 109.070 116.396 142.294 1.00 61.36  ? 50  GLU H OE1 1 
ATOM   9245  O  OE2 . GLU D 4 50  ? 109.558 114.951 140.825 1.00 83.56  ? 50  GLU H OE2 1 
ATOM   9246  N  N   . ILE D 4 51  ? 114.390 117.277 141.702 1.00 59.33  ? 51  ILE H N   1 
ATOM   9247  C  CA  . ILE D 4 51  ? 115.634 116.587 141.451 1.00 64.30  ? 51  ILE H CA  1 
ATOM   9248  C  C   . ILE D 4 51  ? 115.626 115.428 142.403 1.00 64.07  ? 51  ILE H C   1 
ATOM   9249  O  O   . ILE D 4 51  ? 115.180 115.587 143.513 1.00 68.45  ? 51  ILE H O   1 
ATOM   9250  C  CB  . ILE D 4 51  ? 116.861 117.519 141.656 1.00 66.45  ? 51  ILE H CB  1 
ATOM   9251  C  CG1 . ILE D 4 51  ? 118.196 116.822 141.807 1.00 75.57  ? 51  ILE H CG1 1 
ATOM   9252  C  CG2 . ILE D 4 51  ? 116.737 118.396 142.856 1.00 80.83  ? 51  ILE H CG2 1 
ATOM   9253  C  CD1 . ILE D 4 51  ? 118.718 116.342 140.492 1.00 145.91 ? 51  ILE H CD1 1 
ATOM   9254  N  N   . ASP D 4 52  ? 116.170 114.315 141.940 1.00 86.95  ? 52  ASP H N   1 
ATOM   9255  C  CA  . ASP D 4 52  ? 116.328 113.128 142.732 1.00 95.61  ? 52  ASP H CA  1 
ATOM   9256  C  C   . ASP D 4 52  ? 117.792 112.984 143.165 1.00 99.31  ? 52  ASP H C   1 
ATOM   9257  O  O   . ASP D 4 52  ? 118.658 112.706 142.334 1.00 126.95 ? 52  ASP H O   1 
ATOM   9258  C  CB  . ASP D 4 52  ? 115.829 111.946 141.927 1.00 68.69  ? 52  ASP H CB  1 
ATOM   9259  C  CG  . ASP D 4 52  ? 115.865 110.663 142.735 1.00 118.92 ? 52  ASP H CG  1 
ATOM   9260  O  OD1 . ASP D 4 52  ? 116.598 110.587 143.813 1.00 123.39 ? 52  ASP H OD1 1 
ATOM   9261  O  OD2 . ASP D 4 52  ? 115.150 109.711 142.287 1.00 134.69 ? 52  ASP H OD2 1 
ATOM   9262  N  N   . PRO D 4 53  ? 118.129 113.124 144.452 1.00 77.85  ? 53  PRO H N   1 
ATOM   9263  C  CA  . PRO D 4 53  ? 119.500 112.998 144.838 1.00 94.83  ? 53  PRO H CA  1 
ATOM   9264  C  C   . PRO D 4 53  ? 120.111 111.620 144.635 1.00 111.67 ? 53  PRO H C   1 
ATOM   9265  O  O   . PRO D 4 53  ? 121.353 111.542 144.689 1.00 199.57 ? 53  PRO H O   1 
ATOM   9266  C  CB  . PRO D 4 53  ? 119.461 113.301 146.339 1.00 121.46 ? 53  PRO H CB  1 
ATOM   9267  C  CG  . PRO D 4 53  ? 118.229 114.073 146.539 1.00 131.60 ? 53  PRO H CG  1 
ATOM   9268  C  CD  . PRO D 4 53  ? 117.271 113.404 145.600 1.00 105.81 ? 53  PRO H CD  1 
ATOM   9269  N  N   . SER D 4 54  ? 119.287 110.581 144.436 1.00 85.81  ? 54  SER H N   1 
ATOM   9270  C  CA  . SER D 4 54  ? 119.842 109.252 144.240 1.00 142.56 ? 54  SER H CA  1 
ATOM   9271  C  C   . SER D 4 54  ? 120.481 109.013 142.849 1.00 127.46 ? 54  SER H C   1 
ATOM   9272  O  O   . SER D 4 54  ? 121.246 108.054 142.707 1.00 194.76 ? 54  SER H O   1 
ATOM   9273  C  CB  . SER D 4 54  ? 118.808 108.205 144.587 1.00 170.75 ? 54  SER H CB  1 
ATOM   9274  O  OG  . SER D 4 54  ? 117.699 108.227 143.700 1.00 276.59 ? 54  SER H OG  1 
ATOM   9275  N  N   . ASP D 4 55  ? 120.182 109.832 141.827 1.00 94.03  ? 55  ASP H N   1 
ATOM   9276  C  CA  . ASP D 4 55  ? 120.721 109.626 140.490 1.00 153.42 ? 55  ASP H CA  1 
ATOM   9277  C  C   . ASP D 4 55  ? 120.763 110.908 139.644 1.00 127.96 ? 55  ASP H C   1 
ATOM   9278  O  O   . ASP D 4 55  ? 121.032 110.839 138.425 1.00 124.02 ? 55  ASP H O   1 
ATOM   9279  C  CB  . ASP D 4 55  ? 119.943 108.490 139.775 1.00 209.77 ? 55  ASP H CB  1 
ATOM   9280  C  CG  . ASP D 4 55  ? 118.450 108.689 139.511 1.00 195.35 ? 55  ASP H CG  1 
ATOM   9281  O  OD1 . ASP D 4 55  ? 118.062 109.833 139.304 1.00 198.92 ? 55  ASP H OD1 1 
ATOM   9282  O  OD2 . ASP D 4 55  ? 117.685 107.680 139.530 1.00 176.16 ? 55  ASP H OD2 1 
ATOM   9283  N  N   . SER D 4 56  ? 120.496 112.054 140.266 1.00 88.18  ? 56  SER H N   1 
ATOM   9284  C  CA  . SER D 4 56  ? 120.536 113.344 139.591 1.00 132.66 ? 56  SER H CA  1 
ATOM   9285  C  C   . SER D 4 56  ? 119.568 113.557 138.395 1.00 138.93 ? 56  SER H C   1 
ATOM   9286  O  O   . SER D 4 56  ? 119.690 114.568 137.680 1.00 107.34 ? 56  SER H O   1 
ATOM   9287  C  CB  . SER D 4 56  ? 121.968 113.691 139.227 1.00 180.58 ? 56  SER H CB  1 
ATOM   9288  O  OG  . SER D 4 56  ? 122.825 113.546 140.357 1.00 214.11 ? 56  SER H OG  1 
ATOM   9289  N  N   . TYR D 4 57  ? 118.575 112.672 138.179 1.00 134.83 ? 57  TYR H N   1 
ATOM   9290  C  CA  . TYR D 4 57  ? 117.427 112.944 137.316 1.00 105.55 ? 57  TYR H CA  1 
ATOM   9291  C  C   . TYR D 4 57  ? 116.652 114.147 137.815 1.00 70.50  ? 57  TYR H C   1 
ATOM   9292  O  O   . TYR D 4 57  ? 116.492 114.275 139.029 1.00 104.36 ? 57  TYR H O   1 
ATOM   9293  C  CB  . TYR D 4 57  ? 116.392 111.807 137.331 1.00 87.56  ? 57  TYR H CB  1 
ATOM   9294  C  CG  . TYR D 4 57  ? 115.295 112.104 136.324 1.00 84.62  ? 57  TYR H CG  1 
ATOM   9295  C  CD1 . TYR D 4 57  ? 115.562 112.187 134.985 1.00 124.49 ? 57  TYR H CD1 1 
ATOM   9296  C  CD2 . TYR D 4 57  ? 114.002 112.371 136.706 1.00 115.39 ? 57  TYR H CD2 1 
ATOM   9297  C  CE1 . TYR D 4 57  ? 114.578 112.477 134.072 1.00 110.33 ? 57  TYR H CE1 1 
ATOM   9298  C  CE2 . TYR D 4 57  ? 112.998 112.675 135.799 1.00 79.88  ? 57  TYR H CE2 1 
ATOM   9299  C  CZ  . TYR D 4 57  ? 113.297 112.702 134.476 1.00 87.76  ? 57  TYR H CZ  1 
ATOM   9300  O  OH  . TYR D 4 57  ? 112.480 112.960 133.449 1.00 137.50 ? 57  TYR H OH  1 
ATOM   9301  N  N   . SER D 4 58  ? 116.157 114.988 136.907 1.00 65.71  ? 58  SER H N   1 
ATOM   9302  C  CA  . SER D 4 58  ? 115.346 116.133 137.326 1.00 68.56  ? 58  SER H CA  1 
ATOM   9303  C  C   . SER D 4 58  ? 114.279 116.480 136.282 1.00 51.76  ? 58  SER H C   1 
ATOM   9304  O  O   . SER D 4 58  ? 114.448 116.236 135.094 1.00 77.32  ? 58  SER H O   1 
ATOM   9305  C  CB  . SER D 4 58  ? 116.219 117.292 137.624 1.00 80.82  ? 58  SER H CB  1 
ATOM   9306  O  OG  . SER D 4 58  ? 117.084 117.587 136.554 1.00 111.85 ? 58  SER H OG  1 
ATOM   9307  N  N   . TYR D 4 59  ? 113.194 117.016 136.773 1.00 42.08  ? 59  TYR H N   1 
ATOM   9308  C  CA  . TYR D 4 59  ? 111.940 117.128 136.052 1.00 54.17  ? 59  TYR H CA  1 
ATOM   9309  C  C   . TYR D 4 59  ? 111.493 118.571 136.226 1.00 61.37  ? 59  TYR H C   1 
ATOM   9310  O  O   . TYR D 4 59  ? 111.539 119.082 137.352 1.00 84.72  ? 59  TYR H O   1 
ATOM   9311  C  CB  . TYR D 4 59  ? 110.903 116.116 136.591 1.00 49.93  ? 59  TYR H CB  1 
ATOM   9312  C  CG  . TYR D 4 59  ? 109.657 116.011 135.733 1.00 51.68  ? 59  TYR H CG  1 
ATOM   9313  C  CD1 . TYR D 4 59  ? 109.648 115.141 134.721 1.00 65.46  ? 59  TYR H CD1 1 
ATOM   9314  C  CD2 . TYR D 4 59  ? 108.502 116.758 135.882 1.00 60.83  ? 59  TYR H CD2 1 
ATOM   9315  C  CE1 . TYR D 4 59  ? 108.575 115.027 133.853 1.00 90.01  ? 59  TYR H CE1 1 
ATOM   9316  C  CE2 . TYR D 4 59  ? 107.428 116.651 135.037 1.00 71.34  ? 59  TYR H CE2 1 
ATOM   9317  C  CZ  . TYR D 4 59  ? 107.455 115.782 134.001 1.00 70.37  ? 59  TYR H CZ  1 
ATOM   9318  O  OH  . TYR D 4 59  ? 106.449 115.596 133.131 1.00 105.60 ? 59  TYR H OH  1 
ATOM   9319  N  N   . TYR D 4 60  ? 111.098 119.246 135.140 1.00 51.08  ? 60  TYR H N   1 
ATOM   9320  C  CA  . TYR D 4 60  ? 110.956 120.687 135.263 1.00 73.09  ? 60  TYR H CA  1 
ATOM   9321  C  C   . TYR D 4 60  ? 109.694 121.193 134.633 1.00 70.87  ? 60  TYR H C   1 
ATOM   9322  O  O   . TYR D 4 60  ? 109.263 120.543 133.676 1.00 72.06  ? 60  TYR H O   1 
ATOM   9323  C  CB  . TYR D 4 60  ? 111.955 121.497 134.454 1.00 87.14  ? 60  TYR H CB  1 
ATOM   9324  C  CG  . TYR D 4 60  ? 113.396 121.203 134.763 1.00 68.42  ? 60  TYR H CG  1 
ATOM   9325  C  CD1 . TYR D 4 60  ? 113.931 121.686 135.890 1.00 73.98  ? 60  TYR H CD1 1 
ATOM   9326  C  CD2 . TYR D 4 60  ? 114.176 120.470 133.943 1.00 93.58  ? 60  TYR H CD2 1 
ATOM   9327  C  CE1 . TYR D 4 60  ? 115.256 121.496 136.213 1.00 71.32  ? 60  TYR H CE1 1 
ATOM   9328  C  CE2 . TYR D 4 60  ? 115.468 120.230 134.259 1.00 125.19 ? 60  TYR H CE2 1 
ATOM   9329  C  CZ  . TYR D 4 60  ? 116.009 120.720 135.410 1.00 83.68  ? 60  TYR H CZ  1 
ATOM   9330  O  OH  . TYR D 4 60  ? 117.309 120.401 135.608 1.00 127.76 ? 60  TYR H OH  1 
ATOM   9331  N  N   . SER D 4 61  ? 109.155 122.316 135.172 1.00 50.72  ? 61  SER H N   1 
ATOM   9332  C  CA  . SER D 4 61  ? 107.865 122.710 134.632 1.00 72.23  ? 61  SER H CA  1 
ATOM   9333  C  C   . SER D 4 61  ? 108.102 123.167 133.210 1.00 88.49  ? 61  SER H C   1 
ATOM   9334  O  O   . SER D 4 61  ? 109.207 123.522 132.911 1.00 91.11  ? 61  SER H O   1 
ATOM   9335  C  CB  . SER D 4 61  ? 107.116 123.729 135.462 1.00 113.43 ? 61  SER H CB  1 
ATOM   9336  O  OG  . SER D 4 61  ? 107.918 124.811 135.801 1.00 81.22  ? 61  SER H OG  1 
ATOM   9337  N  N   . GLN D 4 62  ? 107.084 123.185 132.359 1.00 111.01 ? 62  GLN H N   1 
ATOM   9338  C  CA  . GLN D 4 62  ? 107.285 123.592 130.973 1.00 140.29 ? 62  GLN H CA  1 
ATOM   9339  C  C   . GLN D 4 62  ? 107.859 125.024 130.835 1.00 147.39 ? 62  GLN H C   1 
ATOM   9340  O  O   . GLN D 4 62  ? 108.624 125.319 129.909 1.00 100.69 ? 62  GLN H O   1 
ATOM   9341  C  CB  . GLN D 4 62  ? 105.927 123.466 130.280 1.00 209.16 ? 62  GLN H CB  1 
ATOM   9342  C  CG  . GLN D 4 62  ? 106.026 123.295 128.778 1.00 251.63 ? 62  GLN H CG  1 
ATOM   9343  C  CD  . GLN D 4 62  ? 106.598 121.946 128.440 1.00 216.50 ? 62  GLN H CD  1 
ATOM   9344  O  OE1 . GLN D 4 62  ? 107.814 121.781 128.385 1.00 165.85 ? 62  GLN H OE1 1 
ATOM   9345  N  NE2 . GLN D 4 62  ? 105.714 120.982 128.214 1.00 277.54 ? 62  GLN H NE2 1 
ATOM   9346  N  N   . ASN D 4 63  ? 107.497 125.921 131.772 1.00 148.46 ? 63  ASN H N   1 
ATOM   9347  C  CA  . ASN D 4 63  ? 107.943 127.305 131.787 1.00 116.06 ? 63  ASN H CA  1 
ATOM   9348  C  C   . ASN D 4 63  ? 109.433 127.437 132.043 1.00 98.49  ? 63  ASN H C   1 
ATOM   9349  O  O   . ASN D 4 63  ? 109.999 128.457 131.623 1.00 208.15 ? 63  ASN H O   1 
ATOM   9350  C  CB  . ASN D 4 63  ? 107.223 128.146 132.843 1.00 159.34 ? 63  ASN H CB  1 
ATOM   9351  C  CG  . ASN D 4 63  ? 105.721 128.230 132.637 1.00 268.85 ? 63  ASN H CG  1 
ATOM   9352  O  OD1 . ASN D 4 63  ? 105.201 127.918 131.564 1.00 274.32 ? 63  ASN H OD1 1 
ATOM   9353  N  ND2 . ASN D 4 63  ? 105.013 128.656 133.671 1.00 357.47 ? 63  ASN H ND2 1 
ATOM   9354  N  N   . PHE D 4 64  ? 110.075 126.464 132.686 1.00 65.20  ? 64  PHE H N   1 
ATOM   9355  C  CA  . PHE D 4 64  ? 111.475 126.583 133.064 1.00 89.12  ? 64  PHE H CA  1 
ATOM   9356  C  C   . PHE D 4 64  ? 112.420 125.699 132.236 1.00 103.75 ? 64  PHE H C   1 
ATOM   9357  O  O   . PHE D 4 64  ? 113.618 125.679 132.498 1.00 140.66 ? 64  PHE H O   1 
ATOM   9358  C  CB  . PHE D 4 64  ? 111.624 126.307 134.567 1.00 96.54  ? 64  PHE H CB  1 
ATOM   9359  C  CG  . PHE D 4 64  ? 111.076 127.435 135.386 1.00 94.39  ? 64  PHE H CG  1 
ATOM   9360  C  CD1 . PHE D 4 64  ? 109.726 127.540 135.557 1.00 98.71  ? 64  PHE H CD1 1 
ATOM   9361  C  CD2 . PHE D 4 64  ? 111.898 128.390 135.932 1.00 121.03 ? 64  PHE H CD2 1 
ATOM   9362  C  CE1 . PHE D 4 64  ? 109.197 128.589 136.264 1.00 135.25 ? 64  PHE H CE1 1 
ATOM   9363  C  CE2 . PHE D 4 64  ? 111.372 129.444 136.648 1.00 120.53 ? 64  PHE H CE2 1 
ATOM   9364  C  CZ  . PHE D 4 64  ? 110.022 129.531 136.810 1.00 128.07 ? 64  PHE H CZ  1 
ATOM   9365  N  N   . LYS D 4 65  ? 111.922 124.968 131.252 1.00 115.94 ? 65  LYS H N   1 
ATOM   9366  C  CA  . LYS D 4 65  ? 112.682 123.862 130.706 1.00 133.70 ? 65  LYS H CA  1 
ATOM   9367  C  C   . LYS D 4 65  ? 113.847 124.463 129.939 1.00 149.61 ? 65  LYS H C   1 
ATOM   9368  O  O   . LYS D 4 65  ? 113.622 125.242 129.017 1.00 164.90 ? 65  LYS H O   1 
ATOM   9369  C  CB  . LYS D 4 65  ? 111.751 122.986 129.871 1.00 127.34 ? 65  LYS H CB  1 
ATOM   9370  C  CG  . LYS D 4 65  ? 112.340 121.632 129.558 1.00 162.06 ? 65  LYS H CG  1 
ATOM   9371  C  CD  . LYS D 4 65  ? 111.357 120.729 128.846 1.00 193.91 ? 65  LYS H CD  1 
ATOM   9372  C  CE  . LYS D 4 65  ? 110.299 120.147 129.749 1.00 146.38 ? 65  LYS H CE  1 
ATOM   9373  N  NZ  . LYS D 4 65  ? 109.277 119.403 128.984 1.00 150.18 ? 65  LYS H NZ  1 
ATOM   9374  N  N   . GLY D 4 66  ? 115.079 124.115 130.339 1.00 178.28 ? 66  GLY H N   1 
ATOM   9375  C  CA  . GLY D 4 66  ? 116.266 124.680 129.710 1.00 246.64 ? 66  GLY H CA  1 
ATOM   9376  C  C   . GLY D 4 66  ? 116.711 126.026 130.290 1.00 196.39 ? 66  GLY H C   1 
ATOM   9377  O  O   . GLY D 4 66  ? 117.915 126.286 130.279 1.00 162.40 ? 66  GLY H O   1 
ATOM   9378  N  N   . LYS D 4 67  ? 115.761 126.852 130.771 1.00 157.39 ? 67  LYS H N   1 
ATOM   9379  C  CA  . LYS D 4 67  ? 116.045 128.050 131.559 1.00 191.98 ? 67  LYS H CA  1 
ATOM   9380  C  C   . LYS D 4 67  ? 116.645 127.738 132.950 1.00 173.30 ? 67  LYS H C   1 
ATOM   9381  O  O   . LYS D 4 67  ? 117.522 128.464 133.409 1.00 182.13 ? 67  LYS H O   1 
ATOM   9382  C  CB  . LYS D 4 67  ? 114.759 128.882 131.664 1.00 183.97 ? 67  LYS H CB  1 
ATOM   9383  C  CG  . LYS D 4 67  ? 114.857 130.173 132.481 1.00 205.02 ? 67  LYS H CG  1 
ATOM   9384  C  CD  . LYS D 4 67  ? 113.543 130.879 132.752 1.00 254.41 ? 67  LYS H CD  1 
ATOM   9385  C  CE  . LYS D 4 67  ? 112.892 131.475 131.517 1.00 372.21 ? 67  LYS H CE  1 
ATOM   9386  N  NZ  . LYS D 4 67  ? 112.066 130.531 130.717 1.00 423.93 ? 67  LYS H NZ  1 
ATOM   9387  N  N   . ALA D 4 68  ? 116.163 126.680 133.617 1.00 165.98 ? 68  ALA H N   1 
ATOM   9388  C  CA  . ALA D 4 68  ? 116.704 126.171 134.871 1.00 134.19 ? 68  ALA H CA  1 
ATOM   9389  C  C   . ALA D 4 68  ? 117.658 125.006 134.650 1.00 111.45 ? 68  ALA H C   1 
ATOM   9390  O  O   . ALA D 4 68  ? 117.775 124.498 133.535 1.00 159.11 ? 68  ALA H O   1 
ATOM   9391  C  CB  . ALA D 4 68  ? 115.583 125.686 135.725 1.00 121.33 ? 68  ALA H CB  1 
ATOM   9392  N  N   . THR D 4 69  ? 118.332 124.614 135.729 1.00 95.12  ? 69  THR H N   1 
ATOM   9393  C  CA  . THR D 4 69  ? 119.184 123.445 135.751 1.00 115.30 ? 69  THR H CA  1 
ATOM   9394  C  C   . THR D 4 69  ? 119.471 123.059 137.197 1.00 110.23 ? 69  THR H C   1 
ATOM   9395  O  O   . THR D 4 69  ? 120.182 123.779 137.909 1.00 143.98 ? 69  THR H O   1 
ATOM   9396  C  CB  . THR D 4 69  ? 120.524 123.658 135.036 1.00 161.81 ? 69  THR H CB  1 
ATOM   9397  O  OG1 . THR D 4 69  ? 120.383 123.898 133.633 1.00 220.93 ? 69  THR H OG1 1 
ATOM   9398  C  CG2 . THR D 4 69  ? 121.458 122.468 135.200 1.00 179.72 ? 69  THR H CG2 1 
ATOM   9399  N  N   . LEU D 4 70  ? 118.917 121.927 137.634 1.00 100.08 ? 70  LEU H N   1 
ATOM   9400  C  CA  . LEU D 4 70  ? 119.103 121.448 138.997 1.00 114.52 ? 70  LEU H CA  1 
ATOM   9401  C  C   . LEU D 4 70  ? 120.242 120.467 138.956 1.00 130.98 ? 70  LEU H C   1 
ATOM   9402  O  O   . LEU D 4 70  ? 120.353 119.653 138.020 1.00 181.21 ? 70  LEU H O   1 
ATOM   9403  C  CB  . LEU D 4 70  ? 117.870 120.713 139.523 1.00 100.26 ? 70  LEU H CB  1 
ATOM   9404  C  CG  . LEU D 4 70  ? 116.820 121.542 140.223 1.00 93.99  ? 70  LEU H CG  1 
ATOM   9405  C  CD1 . LEU D 4 70  ? 116.669 122.918 139.630 1.00 126.71 ? 70  LEU H CD1 1 
ATOM   9406  C  CD2 . LEU D 4 70  ? 115.444 120.853 140.167 1.00 97.05  ? 70  LEU H CD2 1 
ATOM   9407  N  N   . THR D 4 71  ? 121.062 120.522 140.015 1.00 98.93  ? 71  THR H N   1 
ATOM   9408  C  CA  . THR D 4 71  ? 121.968 119.413 140.305 1.00 121.86 ? 71  THR H CA  1 
ATOM   9409  C  C   . THR D 4 71  ? 121.935 119.174 141.801 1.00 98.40  ? 71  THR H C   1 
ATOM   9410  O  O   . THR D 4 71  ? 121.104 119.819 142.504 1.00 75.93  ? 71  THR H O   1 
ATOM   9411  C  CB  . THR D 4 71  ? 123.388 119.617 139.756 1.00 158.88 ? 71  THR H CB  1 
ATOM   9412  O  OG1 . THR D 4 71  ? 123.955 120.778 140.377 1.00 247.94 ? 71  THR H OG1 1 
ATOM   9413  C  CG2 . THR D 4 71  ? 123.417 119.747 138.249 1.00 231.47 ? 71  THR H CG2 1 
ATOM   9414  N  N   . VAL D 4 72  ? 122.849 118.261 142.207 1.00 82.87  ? 72  VAL H N   1 
ATOM   9415  C  CA  . VAL D 4 72  ? 122.906 117.850 143.584 1.00 100.46 ? 72  VAL H CA  1 
ATOM   9416  C  C   . VAL D 4 72  ? 124.313 117.362 143.955 1.00 136.37 ? 72  VAL H C   1 
ATOM   9417  O  O   . VAL D 4 72  ? 125.096 116.977 143.088 1.00 134.29 ? 72  VAL H O   1 
ATOM   9418  C  CB  . VAL D 4 72  ? 121.795 116.795 143.718 1.00 110.02 ? 72  VAL H CB  1 
ATOM   9419  C  CG1 . VAL D 4 72  ? 122.163 115.513 142.976 1.00 179.19 ? 72  VAL H CG1 1 
ATOM   9420  C  CG2 . VAL D 4 72  ? 121.408 116.541 145.153 1.00 93.93  ? 72  VAL H CG2 1 
ATOM   9421  N  N   . ASP D 4 73  ? 124.600 117.378 145.271 1.00 170.70 ? 73  ASP H N   1 
ATOM   9422  C  CA  . ASP D 4 73  ? 125.863 116.930 145.850 1.00 160.25 ? 73  ASP H CA  1 
ATOM   9423  C  C   . ASP D 4 73  ? 125.569 116.083 147.090 1.00 166.88 ? 73  ASP H C   1 
ATOM   9424  O  O   . ASP D 4 73  ? 125.321 116.606 148.202 1.00 190.33 ? 73  ASP H O   1 
ATOM   9425  C  CB  . ASP D 4 73  ? 126.759 118.118 146.210 1.00 227.31 ? 73  ASP H CB  1 
ATOM   9426  C  CG  . ASP D 4 73  ? 127.886 117.789 147.185 1.00 256.28 ? 73  ASP H CG  1 
ATOM   9427  O  OD1 . ASP D 4 73  ? 128.347 116.629 147.186 1.00 311.93 ? 73  ASP H OD1 1 
ATOM   9428  O  OD2 . ASP D 4 73  ? 128.281 118.688 147.957 1.00 209.06 ? 73  ASP H OD2 1 
ATOM   9429  N  N   . GLN D 4 74  ? 125.620 114.756 146.893 1.00 166.46 ? 74  GLN H N   1 
ATOM   9430  C  CA  . GLN D 4 74  ? 125.310 113.786 147.941 1.00 189.15 ? 74  GLN H CA  1 
ATOM   9431  C  C   . GLN D 4 74  ? 126.328 113.812 149.086 1.00 249.29 ? 74  GLN H C   1 
ATOM   9432  O  O   . GLN D 4 74  ? 126.012 113.331 150.178 1.00 219.53 ? 74  GLN H O   1 
ATOM   9433  C  CB  . GLN D 4 74  ? 125.254 112.373 147.350 1.00 162.33 ? 74  GLN H CB  1 
ATOM   9434  C  CG  . GLN D 4 74  ? 124.143 112.216 146.346 1.00 187.06 ? 74  GLN H CG  1 
ATOM   9435  C  CD  . GLN D 4 74  ? 124.477 111.353 145.160 1.00 254.36 ? 74  GLN H CD  1 
ATOM   9436  O  OE1 . GLN D 4 74  ? 124.746 111.848 144.066 1.00 233.38 ? 74  GLN H OE1 1 
ATOM   9437  N  NE2 . GLN D 4 74  ? 124.449 110.050 145.379 1.00 304.17 ? 74  GLN H NE2 1 
ATOM   9438  N  N   . SER D 4 75  ? 127.537 114.354 148.837 1.00 288.27 ? 75  SER H N   1 
ATOM   9439  C  CA  . SER D 4 75  ? 128.596 114.348 149.832 1.00 291.24 ? 75  SER H CA  1 
ATOM   9440  C  C   . SER D 4 75  ? 128.314 115.353 150.956 1.00 269.31 ? 75  SER H C   1 
ATOM   9441  O  O   . SER D 4 75  ? 128.912 115.215 152.024 1.00 330.00 ? 75  SER H O   1 
ATOM   9442  C  CB  . SER D 4 75  ? 129.954 114.562 149.181 1.00 258.36 ? 75  SER H CB  1 
ATOM   9443  O  OG  . SER D 4 75  ? 130.158 115.923 148.830 1.00 301.44 ? 75  SER H OG  1 
ATOM   9444  N  N   . SER D 4 76  ? 127.425 116.342 150.723 1.00 186.07 ? 76  SER H N   1 
ATOM   9445  C  CA  . SER D 4 76  ? 127.124 117.376 151.704 1.00 214.42 ? 76  SER H CA  1 
ATOM   9446  C  C   . SER D 4 76  ? 125.628 117.558 151.989 1.00 191.77 ? 76  SER H C   1 
ATOM   9447  O  O   . SER D 4 76  ? 125.272 118.459 152.748 1.00 194.47 ? 76  SER H O   1 
ATOM   9448  C  CB  . SER D 4 76  ? 127.742 118.676 151.249 1.00 236.24 ? 76  SER H CB  1 
ATOM   9449  O  OG  . SER D 4 76  ? 127.069 119.204 150.121 1.00 174.81 ? 76  SER H OG  1 
ATOM   9450  N  N   . ASN D 4 77  ? 124.772 116.712 151.409 1.00 147.36 ? 77  ASN H N   1 
ATOM   9451  C  CA  . ASN D 4 77  ? 123.333 116.917 151.415 1.00 154.42 ? 77  ASN H CA  1 
ATOM   9452  C  C   . ASN D 4 77  ? 122.935 118.273 150.800 1.00 124.79 ? 77  ASN H C   1 
ATOM   9453  O  O   . ASN D 4 77  ? 122.001 118.907 151.300 1.00 168.06 ? 77  ASN H O   1 
ATOM   9454  C  CB  . ASN D 4 77  ? 122.730 116.770 152.831 1.00 141.46 ? 77  ASN H CB  1 
ATOM   9455  C  CG  . ASN D 4 77  ? 123.155 115.550 153.614 1.00 204.04 ? 77  ASN H CG  1 
ATOM   9456  O  OD1 . ASN D 4 77  ? 123.598 114.540 153.062 1.00 204.14 ? 77  ASN H OD1 1 
ATOM   9457  N  ND2 . ASN D 4 77  ? 122.998 115.654 154.925 1.00 250.91 ? 77  ASN H ND2 1 
ATOM   9458  N  N   . THR D 4 78  ? 123.596 118.717 149.727 1.00 105.64 ? 78  THR H N   1 
ATOM   9459  C  CA  . THR D 4 78  ? 123.249 119.998 149.133 1.00 138.91 ? 78  THR H CA  1 
ATOM   9460  C  C   . THR D 4 78  ? 122.602 119.791 147.764 1.00 130.90 ? 78  THR H C   1 
ATOM   9461  O  O   . THR D 4 78  ? 123.047 118.984 146.968 1.00 135.09 ? 78  THR H O   1 
ATOM   9462  C  CB  . THR D 4 78  ? 124.462 120.926 148.980 1.00 183.55 ? 78  THR H CB  1 
ATOM   9463  O  OG1 . THR D 4 78  ? 125.096 121.114 150.244 1.00 229.81 ? 78  THR H OG1 1 
ATOM   9464  C  CG2 . THR D 4 78  ? 124.128 122.292 148.400 1.00 128.96 ? 78  THR H CG2 1 
ATOM   9465  N  N   . ALA D 4 79  ? 121.555 120.568 147.506 1.00 136.60 ? 79  ALA H N   1 
ATOM   9466  C  CA  . ALA D 4 79  ? 120.939 120.705 146.210 1.00 103.03 ? 79  ALA H CA  1 
ATOM   9467  C  C   . ALA D 4 79  ? 121.210 122.100 145.654 1.00 88.17  ? 79  ALA H C   1 
ATOM   9468  O  O   . ALA D 4 79  ? 121.185 123.084 146.382 1.00 126.43 ? 79  ALA H O   1 
ATOM   9469  C  CB  . ALA D 4 79  ? 119.473 120.477 146.453 1.00 131.58 ? 79  ALA H CB  1 
ATOM   9470  N  N   . TYR D 4 80  ? 121.460 122.202 144.355 1.00 113.55 ? 80  TYR H N   1 
ATOM   9471  C  CA  . TYR D 4 80  ? 121.779 123.466 143.707 1.00 117.92 ? 80  TYR H CA  1 
ATOM   9472  C  C   . TYR D 4 80  ? 120.828 123.726 142.558 1.00 114.40 ? 80  TYR H C   1 
ATOM   9473  O  O   . TYR D 4 80  ? 120.694 122.861 141.686 1.00 163.86 ? 80  TYR H O   1 
ATOM   9474  C  CB  . TYR D 4 80  ? 123.175 123.389 143.076 1.00 169.64 ? 80  TYR H CB  1 
ATOM   9475  C  CG  . TYR D 4 80  ? 124.309 123.192 144.070 1.00 195.51 ? 80  TYR H CG  1 
ATOM   9476  C  CD1 . TYR D 4 80  ? 124.856 124.289 144.740 1.00 247.39 ? 80  TYR H CD1 1 
ATOM   9477  C  CD2 . TYR D 4 80  ? 124.818 121.923 144.344 1.00 152.12 ? 80  TYR H CD2 1 
ATOM   9478  C  CE1 . TYR D 4 80  ? 125.885 124.135 145.653 1.00 261.35 ? 80  TYR H CE1 1 
ATOM   9479  C  CE2 . TYR D 4 80  ? 125.851 121.760 145.256 1.00 224.42 ? 80  TYR H CE2 1 
ATOM   9480  C  CZ  . TYR D 4 80  ? 126.389 122.866 145.912 1.00 247.36 ? 80  TYR H CZ  1 
ATOM   9481  O  OH  . TYR D 4 80  ? 127.411 122.725 146.822 1.00 197.32 ? 80  TYR H OH  1 
ATOM   9482  N  N   . LEU D 4 81  ? 120.209 124.901 142.552 1.00 89.87  ? 81  LEU H N   1 
ATOM   9483  C  CA  . LEU D 4 81  ? 119.478 125.337 141.376 1.00 105.60 ? 81  LEU H CA  1 
ATOM   9484  C  C   . LEU D 4 81  ? 120.329 126.369 140.638 1.00 104.45 ? 81  LEU H C   1 
ATOM   9485  O  O   . LEU D 4 81  ? 120.557 127.450 141.201 1.00 112.54 ? 81  LEU H O   1 
ATOM   9486  C  CB  . LEU D 4 81  ? 118.108 125.860 141.826 1.00 72.95  ? 81  LEU H CB  1 
ATOM   9487  C  CG  . LEU D 4 81  ? 117.385 126.845 140.900 1.00 101.63 ? 81  LEU H CG  1 
ATOM   9488  C  CD1 . LEU D 4 81  ? 117.019 126.315 139.527 1.00 94.52  ? 81  LEU H CD1 1 
ATOM   9489  C  CD2 . LEU D 4 81  ? 116.122 127.308 141.557 1.00 111.49 ? 81  LEU H CD2 1 
ATOM   9490  N  N   . GLN D 4 82  ? 120.785 126.034 139.416 1.00 95.09  ? 82  GLN H N   1 
ATOM   9491  C  CA  . GLN D 4 82  ? 121.233 127.082 138.506 1.00 133.04 ? 82  GLN H CA  1 
ATOM   9492  C  C   . GLN D 4 82  ? 120.044 127.684 137.785 1.00 112.38 ? 82  GLN H C   1 
ATOM   9493  O  O   . GLN D 4 82  ? 119.189 126.960 137.292 1.00 159.21 ? 82  GLN H O   1 
ATOM   9494  C  CB  . GLN D 4 82  ? 122.153 126.645 137.373 1.00 154.59 ? 82  GLN H CB  1 
ATOM   9495  C  CG  . GLN D 4 82  ? 123.448 126.011 137.852 1.00 223.73 ? 82  GLN H CG  1 
ATOM   9496  C  CD  . GLN D 4 82  ? 124.511 126.043 136.770 1.00 261.23 ? 82  GLN H CD  1 
ATOM   9497  O  OE1 . GLN D 4 82  ? 124.398 126.769 135.773 1.00 174.61 ? 82  GLN H OE1 1 
ATOM   9498  N  NE2 . GLN D 4 82  ? 125.556 125.245 136.966 1.00 294.10 ? 82  GLN H NE2 1 
ATOM   9499  N  N   . LEU D 4 83  ? 120.017 129.009 137.721 1.00 99.43  ? 83  LEU H N   1 
ATOM   9500  C  CA  . LEU D 4 83  ? 119.108 129.686 136.835 1.00 111.17 ? 83  LEU H CA  1 
ATOM   9501  C  C   . LEU D 4 83  ? 119.902 130.505 135.830 1.00 157.86 ? 83  LEU H C   1 
ATOM   9502  O  O   . LEU D 4 83  ? 120.989 130.979 136.144 1.00 257.53 ? 83  LEU H O   1 
ATOM   9503  C  CB  . LEU D 4 83  ? 118.209 130.524 137.733 1.00 147.22 ? 83  LEU H CB  1 
ATOM   9504  C  CG  . LEU D 4 83  ? 116.771 130.043 137.779 1.00 167.18 ? 83  LEU H CG  1 
ATOM   9505  C  CD1 . LEU D 4 83  ? 116.126 130.610 139.016 1.00 132.65 ? 83  LEU H CD1 1 
ATOM   9506  C  CD2 . LEU D 4 83  ? 116.034 130.430 136.491 1.00 184.15 ? 83  LEU H CD2 1 
ATOM   9507  N  N   . THR D 4 84  ? 119.346 130.668 134.619 1.00 162.41 ? 84  THR H N   1 
ATOM   9508  C  CA  . THR D 4 84  ? 120.068 131.287 133.507 1.00 203.22 ? 84  THR H CA  1 
ATOM   9509  C  C   . THR D 4 84  ? 119.171 132.260 132.730 1.00 199.67 ? 84  THR H C   1 
ATOM   9510  O  O   . THR D 4 84  ? 117.948 132.146 132.767 1.00 270.29 ? 84  THR H O   1 
ATOM   9511  C  CB  . THR D 4 84  ? 120.661 130.193 132.607 1.00 229.67 ? 84  THR H CB  1 
ATOM   9512  O  OG1 . THR D 4 84  ? 119.595 129.600 131.873 1.00 248.26 ? 84  THR H OG1 1 
ATOM   9513  C  CG2 . THR D 4 84  ? 121.408 129.112 133.372 1.00 220.81 ? 84  THR H CG2 1 
ATOM   9514  N  N   . SER D 4 85  ? 119.794 133.210 132.021 1.00 193.10 ? 85  SER H N   1 
ATOM   9515  C  CA  . SER D 4 85  ? 119.134 134.235 131.212 1.00 215.57 ? 85  SER H CA  1 
ATOM   9516  C  C   . SER D 4 85  ? 118.193 135.155 132.012 1.00 188.87 ? 85  SER H C   1 
ATOM   9517  O  O   . SER D 4 85  ? 117.248 135.710 131.435 1.00 163.01 ? 85  SER H O   1 
ATOM   9518  C  CB  . SER D 4 85  ? 118.435 133.622 129.998 1.00 276.92 ? 85  SER H CB  1 
ATOM   9519  O  OG  . SER D 4 85  ? 117.238 132.922 130.333 1.00 288.78 ? 85  SER H OG  1 
ATOM   9520  N  N   . LEU D 4 86  ? 118.470 135.348 133.317 1.00 163.67 ? 86  LEU H N   1 
ATOM   9521  C  CA  . LEU D 4 86  ? 117.592 136.089 134.226 1.00 182.09 ? 86  LEU H CA  1 
ATOM   9522  C  C   . LEU D 4 86  ? 117.287 137.528 133.771 1.00 159.75 ? 86  LEU H C   1 
ATOM   9523  O  O   . LEU D 4 86  ? 118.175 138.345 133.563 1.00 186.02 ? 86  LEU H O   1 
ATOM   9524  C  CB  . LEU D 4 86  ? 118.232 136.124 135.613 1.00 177.01 ? 86  LEU H CB  1 
ATOM   9525  C  CG  . LEU D 4 86  ? 118.125 134.843 136.423 1.00 204.41 ? 86  LEU H CG  1 
ATOM   9526  C  CD1 . LEU D 4 86  ? 118.971 134.946 137.676 1.00 167.04 ? 86  LEU H CD1 1 
ATOM   9527  C  CD2 . LEU D 4 86  ? 116.678 134.543 136.789 1.00 257.02 ? 86  LEU H CD2 1 
ATOM   9528  N  N   . THR D 4 87  ? 115.992 137.822 133.627 1.00 151.12 ? 87  THR H N   1 
ATOM   9529  C  CA  . THR D 4 87  ? 115.453 139.139 133.330 1.00 162.92 ? 87  THR H CA  1 
ATOM   9530  C  C   . THR D 4 87  ? 114.984 139.805 134.620 1.00 140.90 ? 87  THR H C   1 
ATOM   9531  O  O   . THR D 4 87  ? 114.947 139.167 135.659 1.00 155.32 ? 87  THR H O   1 
ATOM   9532  C  CB  . THR D 4 87  ? 114.264 139.015 132.364 1.00 220.26 ? 87  THR H CB  1 
ATOM   9533  O  OG1 . THR D 4 87  ? 113.194 138.351 133.039 1.00 194.38 ? 87  THR H OG1 1 
ATOM   9534  C  CG2 . THR D 4 87  ? 114.578 138.243 131.097 1.00 254.77 ? 87  THR H CG2 1 
ATOM   9535  N  N   . SER D 4 88  ? 114.590 141.084 134.562 1.00 175.51 ? 88  SER H N   1 
ATOM   9536  C  CA  . SER D 4 88  ? 114.053 141.773 135.726 1.00 151.85 ? 88  SER H CA  1 
ATOM   9537  C  C   . SER D 4 88  ? 112.802 141.048 136.219 1.00 187.65 ? 88  SER H C   1 
ATOM   9538  O  O   . SER D 4 88  ? 112.639 140.903 137.432 1.00 252.11 ? 88  SER H O   1 
ATOM   9539  C  CB  . SER D 4 88  ? 113.779 143.224 135.446 1.00 221.13 ? 88  SER H CB  1 
ATOM   9540  O  OG  . SER D 4 88  ? 113.283 143.894 136.594 1.00 237.09 ? 88  SER H OG  1 
ATOM   9541  N  N   . GLU D 4 89  ? 111.950 140.551 135.301 1.00 167.31 ? 89  GLU H N   1 
ATOM   9542  C  CA  . GLU D 4 89  ? 110.751 139.818 135.714 1.00 202.78 ? 89  GLU H CA  1 
ATOM   9543  C  C   . GLU D 4 89  ? 111.020 138.396 136.257 1.00 153.04 ? 89  GLU H C   1 
ATOM   9544  O  O   . GLU D 4 89  ? 110.079 137.703 136.607 1.00 156.19 ? 89  GLU H O   1 
ATOM   9545  C  CB  . GLU D 4 89  ? 109.725 139.778 134.569 1.00 254.18 ? 89  GLU H CB  1 
ATOM   9546  C  CG  . GLU D 4 89  ? 110.092 138.912 133.362 1.00 265.52 ? 89  GLU H CG  1 
ATOM   9547  C  CD  . GLU D 4 89  ? 108.928 138.332 132.561 1.00 350.11 ? 89  GLU H CD  1 
ATOM   9548  O  OE1 . GLU D 4 89  ? 107.808 138.887 132.625 1.00 391.52 ? 89  GLU H OE1 1 
ATOM   9549  O  OE2 . GLU D 4 89  ? 109.145 137.311 131.874 1.00 382.53 ? 89  GLU H OE2 1 
ATOM   9550  N  N   . ASP D 4 90  ? 112.266 137.929 136.344 1.00 163.79 ? 90  ASP H N   1 
ATOM   9551  C  CA  . ASP D 4 90  ? 112.620 136.715 137.077 1.00 123.66 ? 90  ASP H CA  1 
ATOM   9552  C  C   . ASP D 4 90  ? 113.141 137.018 138.495 1.00 120.16 ? 90  ASP H C   1 
ATOM   9553  O  O   . ASP D 4 90  ? 113.631 136.132 139.201 1.00 101.03 ? 90  ASP H O   1 
ATOM   9554  C  CB  . ASP D 4 90  ? 113.666 135.950 136.242 1.00 223.47 ? 90  ASP H CB  1 
ATOM   9555  C  CG  . ASP D 4 90  ? 113.191 135.499 134.860 1.00 246.77 ? 90  ASP H CG  1 
ATOM   9556  O  OD1 . ASP D 4 90  ? 112.182 134.760 134.796 1.00 237.95 ? 90  ASP H OD1 1 
ATOM   9557  O  OD2 . ASP D 4 90  ? 113.823 135.885 133.853 1.00 286.56 ? 90  ASP H OD2 1 
ATOM   9558  N  N   . SER D 4 91  ? 113.084 138.294 138.926 1.00 153.11 ? 91  SER H N   1 
ATOM   9559  C  CA  . SER D 4 91  ? 113.373 138.685 140.295 1.00 138.90 ? 91  SER H CA  1 
ATOM   9560  C  C   . SER D 4 91  ? 112.262 138.104 141.132 1.00 157.88 ? 91  SER H C   1 
ATOM   9561  O  O   . SER D 4 91  ? 111.097 138.251 140.736 1.00 130.55 ? 91  SER H O   1 
ATOM   9562  C  CB  . SER D 4 91  ? 113.388 140.175 140.498 1.00 172.19 ? 91  SER H CB  1 
ATOM   9563  O  OG  . SER D 4 91  ? 114.342 140.808 139.667 1.00 226.93 ? 91  SER H OG  1 
ATOM   9564  N  N   . ALA D 4 92  ? 112.630 137.460 142.251 1.00 168.31 ? 92  ALA H N   1 
ATOM   9565  C  CA  . ALA D 4 92  ? 111.676 136.705 143.059 1.00 136.87 ? 92  ALA H CA  1 
ATOM   9566  C  C   . ALA D 4 92  ? 112.313 136.207 144.345 1.00 117.70 ? 92  ALA H C   1 
ATOM   9567  O  O   . ALA D 4 92  ? 113.488 136.459 144.600 1.00 129.12 ? 92  ALA H O   1 
ATOM   9568  C  CB  . ALA D 4 92  ? 111.204 135.519 142.266 1.00 127.98 ? 92  ALA H CB  1 
ATOM   9569  N  N   . VAL D 4 93  ? 111.522 135.482 145.131 1.00 96.61  ? 93  VAL H N   1 
ATOM   9570  C  CA  . VAL D 4 93  ? 112.080 134.638 146.165 1.00 98.51  ? 93  VAL H CA  1 
ATOM   9571  C  C   . VAL D 4 93  ? 112.053 133.188 145.704 1.00 115.09 ? 93  VAL H C   1 
ATOM   9572  O  O   . VAL D 4 93  ? 111.032 132.737 145.218 1.00 96.12  ? 93  VAL H O   1 
ATOM   9573  C  CB  . VAL D 4 93  ? 111.263 134.727 147.438 1.00 108.05 ? 93  VAL H CB  1 
ATOM   9574  C  CG1 . VAL D 4 93  ? 112.108 134.087 148.522 1.00 88.28  ? 93  VAL H CG1 1 
ATOM   9575  C  CG2 . VAL D 4 93  ? 110.781 136.148 147.749 1.00 151.15 ? 93  VAL H CG2 1 
ATOM   9576  N  N   . TYR D 4 94  ? 113.174 132.482 145.890 1.00 119.37 ? 94  TYR H N   1 
ATOM   9577  C  CA  . TYR D 4 94  ? 113.323 131.103 145.465 1.00 103.10 ? 94  TYR H CA  1 
ATOM   9578  C  C   . TYR D 4 94  ? 113.409 130.252 146.723 1.00 88.94  ? 94  TYR H C   1 
ATOM   9579  O  O   . TYR D 4 94  ? 114.288 130.442 147.552 1.00 74.41  ? 94  TYR H O   1 
ATOM   9580  C  CB  . TYR D 4 94  ? 114.539 130.926 144.522 1.00 89.23  ? 94  TYR H CB  1 
ATOM   9581  C  CG  . TYR D 4 94  ? 114.263 131.613 143.187 1.00 69.33  ? 94  TYR H CG  1 
ATOM   9582  C  CD1 . TYR D 4 94  ? 114.530 132.918 142.954 1.00 103.85 ? 94  TYR H CD1 1 
ATOM   9583  C  CD2 . TYR D 4 94  ? 113.663 130.964 142.186 1.00 92.65  ? 94  TYR H CD2 1 
ATOM   9584  C  CE1 . TYR D 4 94  ? 114.237 133.531 141.762 1.00 123.08 ? 94  TYR H CE1 1 
ATOM   9585  C  CE2 . TYR D 4 94  ? 113.363 131.545 140.979 1.00 94.83  ? 94  TYR H CE2 1 
ATOM   9586  C  CZ  . TYR D 4 94  ? 113.657 132.838 140.752 1.00 99.43  ? 94  TYR H CZ  1 
ATOM   9587  O  OH  . TYR D 4 94  ? 113.367 133.407 139.559 1.00 128.47 ? 94  TYR H OH  1 
ATOM   9588  N  N   . TYR D 4 95  ? 112.473 129.304 146.814 1.00 108.03 ? 95  TYR H N   1 
ATOM   9589  C  CA  . TYR D 4 95  ? 112.354 128.424 147.947 1.00 113.39 ? 95  TYR H CA  1 
ATOM   9590  C  C   . TYR D 4 95  ? 112.712 126.987 147.571 1.00 98.77  ? 95  TYR H C   1 
ATOM   9591  O  O   . TYR D 4 95  ? 112.233 126.445 146.581 1.00 49.97  ? 95  TYR H O   1 
ATOM   9592  C  CB  . TYR D 4 95  ? 110.911 128.442 148.395 1.00 88.81  ? 95  TYR H CB  1 
ATOM   9593  C  CG  . TYR D 4 95  ? 110.395 129.697 149.075 1.00 89.98  ? 95  TYR H CG  1 
ATOM   9594  C  CD1 . TYR D 4 95  ? 110.665 129.942 150.408 1.00 98.18  ? 95  TYR H CD1 1 
ATOM   9595  C  CD2 . TYR D 4 95  ? 109.601 130.610 148.409 1.00 107.29 ? 95  TYR H CD2 1 
ATOM   9596  C  CE1 . TYR D 4 95  ? 110.172 131.046 151.084 1.00 98.79  ? 95  TYR H CE1 1 
ATOM   9597  C  CE2 . TYR D 4 95  ? 109.084 131.716 149.065 1.00 108.03 ? 95  TYR H CE2 1 
ATOM   9598  C  CZ  . TYR D 4 95  ? 109.380 131.945 150.410 1.00 130.14 ? 95  TYR H CZ  1 
ATOM   9599  O  OH  . TYR D 4 95  ? 108.939 133.029 151.129 1.00 155.48 ? 95  TYR H OH  1 
ATOM   9600  N  N   . CYS D 4 96  ? 113.548 126.399 148.420 1.00 108.26 ? 96  CYS H N   1 
ATOM   9601  C  CA  . CYS D 4 96  ? 113.892 124.998 148.391 1.00 102.51 ? 96  CYS H CA  1 
ATOM   9602  C  C   . CYS D 4 96  ? 112.923 124.235 149.293 1.00 93.00  ? 96  CYS H C   1 
ATOM   9603  O  O   . CYS D 4 96  ? 112.705 124.638 150.410 1.00 101.83 ? 96  CYS H O   1 
ATOM   9604  C  CB  . CYS D 4 96  ? 115.311 124.881 148.901 1.00 102.37 ? 96  CYS H CB  1 
ATOM   9605  S  SG  . CYS D 4 96  ? 115.950 123.203 149.054 1.00 180.01 ? 96  CYS H SG  1 
ATOM   9606  N  N   . ALA D 4 97  ? 112.362 123.124 148.829 1.00 88.85  ? 97  ALA H N   1 
ATOM   9607  C  CA  . ALA D 4 97  ? 111.312 122.404 149.540 1.00 83.10  ? 97  ALA H CA  1 
ATOM   9608  C  C   . ALA D 4 97  ? 111.530 120.877 149.423 1.00 67.45  ? 97  ALA H C   1 
ATOM   9609  O  O   . ALA D 4 97  ? 112.063 120.398 148.459 1.00 62.91  ? 97  ALA H O   1 
ATOM   9610  C  CB  . ALA D 4 97  ? 109.948 122.841 149.014 1.00 95.66  ? 97  ALA H CB  1 
ATOM   9611  N  N   . ARG D 4 98  ? 111.095 120.122 150.429 1.00 78.10  ? 98  ARG H N   1 
ATOM   9612  C  CA  . ARG D 4 98  ? 111.137 118.680 150.504 1.00 70.22  ? 98  ARG H CA  1 
ATOM   9613  C  C   . ARG D 4 98  ? 109.729 118.076 150.491 1.00 70.11  ? 98  ARG H C   1 
ATOM   9614  O  O   . ARG D 4 98  ? 108.755 118.602 150.933 1.00 52.66  ? 98  ARG H O   1 
ATOM   9615  C  CB  . ARG D 4 98  ? 111.842 118.216 151.762 1.00 65.12  ? 98  ARG H CB  1 
ATOM   9616  C  CG  . ARG D 4 98  ? 112.606 116.928 151.540 1.00 90.55  ? 98  ARG H CG  1 
ATOM   9617  C  CD  . ARG D 4 98  ? 112.813 116.024 152.729 1.00 91.35  ? 98  ARG H CD  1 
ATOM   9618  N  NE  . ARG D 4 98  ? 111.597 115.334 153.053 1.00 76.27  ? 98  ARG H NE  1 
ATOM   9619  C  CZ  . ARG D 4 98  ? 111.451 114.545 154.103 1.00 122.96 ? 98  ARG H CZ  1 
ATOM   9620  N  NH1 . ARG D 4 98  ? 110.333 113.846 154.278 1.00 151.56 ? 98  ARG H NH1 1 
ATOM   9621  N  NH2 . ARG D 4 98  ? 112.422 114.468 154.991 1.00 112.27 ? 98  ARG H NH2 1 
ATOM   9622  N  N   . GLY D 4 99  ? 109.609 116.927 149.868 1.00 103.36 ? 99  GLY H N   1 
ATOM   9623  C  CA  . GLY D 4 99  ? 108.335 116.248 149.831 1.00 106.07 ? 99  GLY H CA  1 
ATOM   9624  C  C   . GLY D 4 99  ? 108.131 115.399 151.057 1.00 70.98  ? 99  GLY H C   1 
ATOM   9625  O  O   . GLY D 4 99  ? 109.087 115.131 151.798 1.00 58.42  ? 99  GLY H O   1 
ATOM   9626  N  N   . ARG D 4 100 ? 106.871 114.957 151.192 1.00 66.90  ? 100 ARG H N   1 
ATOM   9627  C  CA  . ARG D 4 100 ? 106.590 114.009 152.256 1.00 86.47  ? 100 ARG H CA  1 
ATOM   9628  C  C   . ARG D 4 100 ? 106.868 112.580 151.822 1.00 83.87  ? 100 ARG H C   1 
ATOM   9629  O  O   . ARG D 4 100 ? 107.730 111.939 152.396 1.00 79.14  ? 100 ARG H O   1 
ATOM   9630  C  CB  . ARG D 4 100 ? 105.187 114.261 152.823 1.00 103.00 ? 100 ARG H CB  1 
ATOM   9631  C  CG  . ARG D 4 100 ? 104.886 113.410 154.048 1.00 113.62 ? 100 ARG H CG  1 
ATOM   9632  C  CD  . ARG D 4 100 ? 106.042 113.523 155.091 1.00 138.47 ? 100 ARG H CD  1 
ATOM   9633  N  NE  . ARG D 4 100 ? 105.582 113.585 156.466 1.00 194.13 ? 100 ARG H NE  1 
ATOM   9634  C  CZ  . ARG D 4 100 ? 104.889 114.581 157.034 1.00 223.30 ? 100 ARG H CZ  1 
ATOM   9635  N  NH1 . ARG D 4 100 ? 104.031 114.319 158.004 1.00 317.14 ? 100 ARG H NH1 1 
ATOM   9636  N  NH2 . ARG D 4 100 ? 104.998 115.827 156.640 1.00 157.82 ? 100 ARG H NH2 1 
ATOM   9637  N  N   . GLN D 4 101 ? 106.105 112.103 150.833 1.00 108.60 ? 101 GLN H N   1 
ATOM   9638  C  CA  . GLN D 4 101 ? 106.380 110.841 150.156 1.00 104.94 ? 101 GLN H CA  1 
ATOM   9639  C  C   . GLN D 4 101 ? 107.486 111.081 149.146 1.00 95.59  ? 101 GLN H C   1 
ATOM   9640  O  O   . GLN D 4 101 ? 107.767 112.240 148.844 1.00 92.02  ? 101 GLN H O   1 
ATOM   9641  C  CB  . GLN D 4 101 ? 105.178 110.294 149.379 1.00 132.52 ? 101 GLN H CB  1 
ATOM   9642  C  CG  . GLN D 4 101 ? 104.411 109.192 150.096 1.00 155.20 ? 101 GLN H CG  1 
ATOM   9643  C  CD  . GLN D 4 101 ? 105.195 107.900 150.094 1.00 239.16 ? 101 GLN H CD  1 
ATOM   9644  O  OE1 . GLN D 4 101 ? 106.429 107.905 150.067 1.00 237.30 ? 101 GLN H OE1 1 
ATOM   9645  N  NE2 . GLN D 4 101 ? 104.490 106.778 150.123 1.00 330.08 ? 101 GLN H NE2 1 
ATOM   9646  N  N   . THR D 4 102 ? 108.090 109.983 148.629 1.00 117.15 ? 102 THR H N   1 
ATOM   9647  C  CA  . THR D 4 102 ? 109.344 110.039 147.877 1.00 114.70 ? 102 THR H CA  1 
ATOM   9648  C  C   . THR D 4 102 ? 109.115 110.637 146.518 1.00 69.47  ? 102 THR H C   1 
ATOM   9649  O  O   . THR D 4 102 ? 108.802 109.839 145.675 1.00 93.26  ? 102 THR H O   1 
ATOM   9650  C  CB  . THR D 4 102 ? 109.993 108.654 147.819 1.00 190.68 ? 102 THR H CB  1 
ATOM   9651  O  OG1 . THR D 4 102 ? 110.499 108.413 149.143 1.00 287.07 ? 102 THR H OG1 1 
ATOM   9652  C  CG2 . THR D 4 102 ? 111.143 108.561 146.843 1.00 265.03 ? 102 THR H CG2 1 
ATOM   9653  N  N   . TYR D 4 103 ? 109.226 111.977 146.366 1.00 56.40  ? 103 TYR H N   1 
ATOM   9654  C  CA  . TYR D 4 103 ? 108.893 112.783 145.158 1.00 77.83  ? 103 TYR H CA  1 
ATOM   9655  C  C   . TYR D 4 103 ? 107.474 113.408 145.004 1.00 75.34  ? 103 TYR H C   1 
ATOM   9656  O  O   . TYR D 4 103 ? 107.337 114.388 144.271 1.00 45.80  ? 103 TYR H O   1 
ATOM   9657  C  CB  . TYR D 4 103 ? 109.160 112.188 143.769 1.00 59.37  ? 103 TYR H CB  1 
ATOM   9658  C  CG  . TYR D 4 103 ? 108.170 111.450 142.904 1.00 50.86  ? 103 TYR H CG  1 
ATOM   9659  C  CD1 . TYR D 4 103 ? 107.288 112.128 142.174 1.00 72.10  ? 103 TYR H CD1 1 
ATOM   9660  C  CD2 . TYR D 4 103 ? 108.145 110.018 142.782 1.00 91.84  ? 103 TYR H CD2 1 
ATOM   9661  C  CE1 . TYR D 4 103 ? 106.401 111.410 141.361 1.00 152.93 ? 103 TYR H CE1 1 
ATOM   9662  C  CE2 . TYR D 4 103 ? 107.272 109.253 141.995 1.00 49.08  ? 103 TYR H CE2 1 
ATOM   9663  C  CZ  . TYR D 4 103 ? 106.387 110.004 141.262 1.00 89.77  ? 103 TYR H CZ  1 
ATOM   9664  O  OH  . TYR D 4 103 ? 105.425 109.567 140.418 1.00 102.20 ? 103 TYR H OH  1 
ATOM   9665  N  N   . TYR D 4 104 ? 106.421 112.912 145.674 1.00 70.54  ? 104 TYR H N   1 
ATOM   9666  C  CA  . TYR D 4 104 ? 105.102 113.480 145.468 1.00 70.59  ? 104 TYR H CA  1 
ATOM   9667  C  C   . TYR D 4 104 ? 105.001 114.924 145.953 1.00 73.87  ? 104 TYR H C   1 
ATOM   9668  O  O   . TYR D 4 104 ? 105.459 115.237 147.039 1.00 94.45  ? 104 TYR H O   1 
ATOM   9669  C  CB  . TYR D 4 104 ? 104.072 112.620 146.177 1.00 78.62  ? 104 TYR H CB  1 
ATOM   9670  C  CG  . TYR D 4 104 ? 103.872 111.222 145.599 1.00 78.01  ? 104 TYR H CG  1 
ATOM   9671  C  CD1 . TYR D 4 104 ? 104.383 110.821 144.400 1.00 84.96  ? 104 TYR H CD1 1 
ATOM   9672  C  CD2 . TYR D 4 104 ? 103.130 110.286 146.292 1.00 111.31 ? 104 TYR H CD2 1 
ATOM   9673  C  CE1 . TYR D 4 104 ? 104.154 109.538 143.930 1.00 116.46 ? 104 TYR H CE1 1 
ATOM   9674  C  CE2 . TYR D 4 104 ? 102.913 109.004 145.853 1.00 132.91 ? 104 TYR H CE2 1 
ATOM   9675  C  CZ  . TYR D 4 104 ? 103.431 108.621 144.642 1.00 139.12 ? 104 TYR H CZ  1 
ATOM   9676  O  OH  . TYR D 4 104 ? 103.281 107.383 144.090 1.00 174.40 ? 104 TYR H OH  1 
ATOM   9677  N  N   . PRO D 4 105 ? 104.404 115.832 145.168 1.00 66.14  ? 105 PRO H N   1 
ATOM   9678  C  CA  . PRO D 4 105 ? 104.457 117.257 145.463 1.00 75.40  ? 105 PRO H CA  1 
ATOM   9679  C  C   . PRO D 4 105 ? 103.462 117.798 146.484 1.00 78.08  ? 105 PRO H C   1 
ATOM   9680  O  O   . PRO D 4 105 ? 102.503 118.443 146.139 1.00 101.76 ? 105 PRO H O   1 
ATOM   9681  C  CB  . PRO D 4 105 ? 104.173 117.907 144.085 1.00 67.68  ? 105 PRO H CB  1 
ATOM   9682  C  CG  . PRO D 4 105 ? 103.368 116.918 143.322 1.00 64.23  ? 105 PRO H CG  1 
ATOM   9683  C  CD  . PRO D 4 105 ? 103.700 115.556 143.919 1.00 64.54  ? 105 PRO H CD  1 
ATOM   9684  N  N   . TRP D 4 106 ? 103.699 117.553 147.757 1.00 91.45  ? 106 TRP H N   1 
ATOM   9685  C  CA  . TRP D 4 106 ? 103.194 118.461 148.769 1.00 80.23  ? 106 TRP H CA  1 
ATOM   9686  C  C   . TRP D 4 106 ? 104.227 118.654 149.823 1.00 83.34  ? 106 TRP H C   1 
ATOM   9687  O  O   . TRP D 4 106 ? 104.950 117.686 150.146 1.00 129.49 ? 106 TRP H O   1 
ATOM   9688  C  CB  . TRP D 4 106 ? 101.934 117.931 149.434 1.00 100.21 ? 106 TRP H CB  1 
ATOM   9689  C  CG  . TRP D 4 106 ? 101.957 116.720 150.316 1.00 89.25  ? 106 TRP H CG  1 
ATOM   9690  C  CD1 . TRP D 4 106 ? 102.174 116.681 151.654 1.00 101.73 ? 106 TRP H CD1 1 
ATOM   9691  C  CD2 . TRP D 4 106 ? 101.668 115.373 149.912 1.00 99.93  ? 106 TRP H CD2 1 
ATOM   9692  N  NE1 . TRP D 4 106 ? 102.063 115.402 152.136 1.00 110.48 ? 106 TRP H NE1 1 
ATOM   9693  C  CE2 . TRP D 4 106 ? 101.752 114.590 151.083 1.00 106.50 ? 106 TRP H CE2 1 
ATOM   9694  C  CE3 . TRP D 4 106 ? 101.360 114.784 148.688 1.00 102.24 ? 106 TRP H CE3 1 
ATOM   9695  C  CZ2 . TRP D 4 106 ? 101.540 113.230 151.065 1.00 111.91 ? 106 TRP H CZ2 1 
ATOM   9696  C  CZ3 . TRP D 4 106 ? 101.164 113.435 148.665 1.00 181.90 ? 106 TRP H CZ3 1 
ATOM   9697  C  CH2 . TRP D 4 106 ? 101.237 112.678 149.849 1.00 146.70 ? 106 TRP H CH2 1 
ATOM   9698  N  N   . PHE D 4 107 ? 104.303 119.891 150.330 1.00 65.57  ? 107 PHE H N   1 
ATOM   9699  C  CA  . PHE D 4 107 ? 105.599 120.342 150.810 1.00 78.72  ? 107 PHE H CA  1 
ATOM   9700  C  C   . PHE D 4 107 ? 105.588 120.667 152.287 1.00 64.89  ? 107 PHE H C   1 
ATOM   9701  O  O   . PHE D 4 107 ? 105.318 121.792 152.643 1.00 87.69  ? 107 PHE H O   1 
ATOM   9702  C  CB  . PHE D 4 107 ? 106.065 121.540 149.986 1.00 84.00  ? 107 PHE H CB  1 
ATOM   9703  C  CG  . PHE D 4 107 ? 106.025 121.327 148.516 1.00 64.89  ? 107 PHE H CG  1 
ATOM   9704  C  CD1 . PHE D 4 107 ? 106.587 120.215 148.014 1.00 61.83  ? 107 PHE H CD1 1 
ATOM   9705  C  CD2 . PHE D 4 107 ? 105.419 122.198 147.669 1.00 83.78  ? 107 PHE H CD2 1 
ATOM   9706  C  CE1 . PHE D 4 107 ? 106.563 119.959 146.660 1.00 78.03  ? 107 PHE H CE1 1 
ATOM   9707  C  CE2 . PHE D 4 107 ? 105.414 121.926 146.315 1.00 108.29 ? 107 PHE H CE2 1 
ATOM   9708  C  CZ  . PHE D 4 107 ? 106.006 120.815 145.805 1.00 69.44  ? 107 PHE H CZ  1 
ATOM   9709  N  N   . PRO D 4 108 ? 105.896 119.728 153.186 1.00 62.63  ? 108 PRO H N   1 
ATOM   9710  C  CA  . PRO D 4 108 ? 105.897 120.058 154.572 1.00 78.29  ? 108 PRO H CA  1 
ATOM   9711  C  C   . PRO D 4 108 ? 107.107 120.884 154.949 1.00 80.39  ? 108 PRO H C   1 
ATOM   9712  O  O   . PRO D 4 108 ? 106.909 121.729 155.850 1.00 102.11 ? 108 PRO H O   1 
ATOM   9713  C  CB  . PRO D 4 108 ? 105.924 118.680 155.212 1.00 105.25 ? 108 PRO H CB  1 
ATOM   9714  C  CG  . PRO D 4 108 ? 106.689 117.856 154.279 1.00 87.90  ? 108 PRO H CG  1 
ATOM   9715  C  CD  . PRO D 4 108 ? 106.217 118.330 152.953 1.00 74.09  ? 108 PRO H CD  1 
ATOM   9716  N  N   . TYR D 4 109 ? 108.293 120.647 154.331 1.00 60.48  ? 109 TYR H N   1 
ATOM   9717  C  CA  . TYR D 4 109 ? 109.493 121.315 154.805 1.00 95.96  ? 109 TYR H CA  1 
ATOM   9718  C  C   . TYR D 4 109 ? 110.009 122.282 153.749 1.00 77.65  ? 109 TYR H C   1 
ATOM   9719  O  O   . TYR D 4 109 ? 110.390 121.831 152.701 1.00 144.63 ? 109 TYR H O   1 
ATOM   9720  C  CB  . TYR D 4 109 ? 110.576 120.319 155.250 1.00 95.43  ? 109 TYR H CB  1 
ATOM   9721  C  CG  . TYR D 4 109 ? 110.058 119.221 156.160 1.00 85.83  ? 109 TYR H CG  1 
ATOM   9722  C  CD1 . TYR D 4 109 ? 109.486 119.506 157.396 1.00 105.01 ? 109 TYR H CD1 1 
ATOM   9723  C  CD2 . TYR D 4 109 ? 110.135 117.890 155.766 1.00 121.27 ? 109 TYR H CD2 1 
ATOM   9724  C  CE1 . TYR D 4 109 ? 108.997 118.482 158.211 1.00 163.49 ? 109 TYR H CE1 1 
ATOM   9725  C  CE2 . TYR D 4 109 ? 109.660 116.865 156.576 1.00 172.74 ? 109 TYR H CE2 1 
ATOM   9726  C  CZ  . TYR D 4 109 ? 109.075 117.152 157.794 1.00 167.55 ? 109 TYR H CZ  1 
ATOM   9727  O  OH  . TYR D 4 109 ? 108.646 116.044 158.475 1.00 155.08 ? 109 TYR H OH  1 
ATOM   9728  N  N   . TRP D 4 110 ? 110.065 123.575 154.062 1.00 77.88  ? 110 TRP H N   1 
ATOM   9729  C  CA  . TRP D 4 110 ? 110.638 124.565 153.199 1.00 88.02  ? 110 TRP H CA  1 
ATOM   9730  C  C   . TRP D 4 110 ? 111.865 125.237 153.837 1.00 103.95 ? 110 TRP H C   1 
ATOM   9731  O  O   . TRP D 4 110 ? 111.886 125.574 155.015 1.00 108.57 ? 110 TRP H O   1 
ATOM   9732  C  CB  . TRP D 4 110 ? 109.582 125.637 152.987 1.00 97.75  ? 110 TRP H CB  1 
ATOM   9733  C  CG  . TRP D 4 110 ? 108.288 125.259 152.363 1.00 73.65  ? 110 TRP H CG  1 
ATOM   9734  C  CD1 . TRP D 4 110 ? 107.397 124.444 152.929 1.00 69.29  ? 110 TRP H CD1 1 
ATOM   9735  C  CD2 . TRP D 4 110 ? 107.720 125.699 151.104 1.00 72.81  ? 110 TRP H CD2 1 
ATOM   9736  N  NE1 . TRP D 4 110 ? 106.308 124.346 152.109 1.00 82.43  ? 110 TRP H NE1 1 
ATOM   9737  C  CE2 . TRP D 4 110 ? 106.472 125.101 150.987 1.00 66.89  ? 110 TRP H CE2 1 
ATOM   9738  C  CE3 . TRP D 4 110 ? 108.114 126.527 150.051 1.00 83.24  ? 110 TRP H CE3 1 
ATOM   9739  C  CZ2 . TRP D 4 110 ? 105.641 125.290 149.883 1.00 82.52  ? 110 TRP H CZ2 1 
ATOM   9740  C  CZ3 . TRP D 4 110 ? 107.300 126.721 148.941 1.00 76.29  ? 110 TRP H CZ3 1 
ATOM   9741  C  CH2 . TRP D 4 110 ? 106.066 126.104 148.855 1.00 77.80  ? 110 TRP H CH2 1 
ATOM   9742  N  N   . GLY D 4 111 ? 112.888 125.476 153.018 1.00 119.18 ? 111 GLY H N   1 
ATOM   9743  C  CA  . GLY D 4 111 ? 113.961 126.389 153.366 1.00 167.62 ? 111 GLY H CA  1 
ATOM   9744  C  C   . GLY D 4 111 ? 113.488 127.838 153.354 1.00 124.56 ? 111 GLY H C   1 
ATOM   9745  O  O   . GLY D 4 111 ? 112.670 128.185 152.555 1.00 91.91  ? 111 GLY H O   1 
ATOM   9746  N  N   . GLN D 4 112 ? 114.042 128.672 154.232 1.00 149.60 ? 112 GLN H N   1 
ATOM   9747  C  CA  . GLN D 4 112 ? 113.797 130.106 154.247 1.00 132.81 ? 112 GLN H CA  1 
ATOM   9748  C  C   . GLN D 4 112 ? 114.301 130.647 152.908 1.00 149.16 ? 112 GLN H C   1 
ATOM   9749  O  O   . GLN D 4 112 ? 115.372 130.228 152.477 1.00 159.55 ? 112 GLN H O   1 
ATOM   9750  C  CB  . GLN D 4 112 ? 114.519 130.752 155.432 1.00 192.41 ? 112 GLN H CB  1 
ATOM   9751  C  CG  . GLN D 4 112 ? 114.369 130.046 156.792 1.00 265.12 ? 112 GLN H CG  1 
ATOM   9752  C  CD  . GLN D 4 112 ? 112.982 129.997 157.404 1.00 329.48 ? 112 GLN H CD  1 
ATOM   9753  O  OE1 . GLN D 4 112 ? 111.981 129.701 156.754 1.00 266.36 ? 112 GLN H OE1 1 
ATOM   9754  N  NE2 . GLN D 4 112 ? 112.906 130.288 158.695 1.00 403.30 ? 112 GLN H NE2 1 
ATOM   9755  N  N   . GLY D 4 113 ? 113.539 131.538 152.236 1.00 133.76 ? 113 GLY H N   1 
ATOM   9756  C  CA  . GLY D 4 113 ? 113.715 131.817 150.798 1.00 107.31 ? 113 GLY H CA  1 
ATOM   9757  C  C   . GLY D 4 113 ? 115.000 132.601 150.455 1.00 109.69 ? 113 GLY H C   1 
ATOM   9758  O  O   . GLY D 4 113 ? 115.454 133.423 151.245 1.00 170.49 ? 113 GLY H O   1 
ATOM   9759  N  N   . THR D 4 114 ? 115.602 132.360 149.285 1.00 121.04 ? 114 THR H N   1 
ATOM   9760  C  CA  . THR D 4 114 ? 116.712 133.158 148.768 1.00 115.29 ? 114 THR H CA  1 
ATOM   9761  C  C   . THR D 4 114 ? 116.158 134.273 147.900 1.00 105.43 ? 114 THR H C   1 
ATOM   9762  O  O   . THR D 4 114 ? 115.495 133.979 146.907 1.00 97.67  ? 114 THR H O   1 
ATOM   9763  C  CB  . THR D 4 114 ? 117.660 132.314 147.897 1.00 152.65 ? 114 THR H CB  1 
ATOM   9764  O  OG1 . THR D 4 114 ? 118.185 131.233 148.666 1.00 155.53 ? 114 THR H OG1 1 
ATOM   9765  C  CG2 . THR D 4 114 ? 118.815 133.101 147.326 1.00 151.23 ? 114 THR H CG2 1 
ATOM   9766  N  N   . LEU D 4 115 ? 116.419 135.533 148.274 1.00 121.01 ? 115 LEU H N   1 
ATOM   9767  C  CA  . LEU D 4 115 ? 115.817 136.641 147.550 1.00 137.47 ? 115 LEU H CA  1 
ATOM   9768  C  C   . LEU D 4 115 ? 116.739 137.017 146.399 1.00 140.63 ? 115 LEU H C   1 
ATOM   9769  O  O   . LEU D 4 115 ? 117.810 137.554 146.638 1.00 136.00 ? 115 LEU H O   1 
ATOM   9770  C  CB  . LEU D 4 115 ? 115.551 137.819 148.493 1.00 138.40 ? 115 LEU H CB  1 
ATOM   9771  C  CG  . LEU D 4 115 ? 114.516 138.824 147.958 1.00 186.00 ? 115 LEU H CG  1 
ATOM   9772  C  CD1 . LEU D 4 115 ? 114.136 139.854 149.021 1.00 260.67 ? 115 LEU H CD1 1 
ATOM   9773  C  CD2 . LEU D 4 115 ? 114.989 139.565 146.705 1.00 224.77 ? 115 LEU H CD2 1 
ATOM   9774  N  N   . VAL D 4 116 ? 116.287 136.749 145.168 1.00 120.03 ? 116 VAL H N   1 
ATOM   9775  C  CA  . VAL D 4 116 ? 117.035 137.026 143.954 1.00 121.00 ? 116 VAL H CA  1 
ATOM   9776  C  C   . VAL D 4 116 ? 116.560 138.321 143.294 1.00 164.93 ? 116 VAL H C   1 
ATOM   9777  O  O   . VAL D 4 116 ? 115.441 138.378 142.777 1.00 120.28 ? 116 VAL H O   1 
ATOM   9778  C  CB  . VAL D 4 116 ? 116.842 135.845 143.003 1.00 133.92 ? 116 VAL H CB  1 
ATOM   9779  C  CG1 . VAL D 4 116 ? 117.232 136.105 141.531 1.00 143.05 ? 116 VAL H CG1 1 
ATOM   9780  C  CG2 . VAL D 4 116 ? 117.547 134.648 143.628 1.00 146.44 ? 116 VAL H CG2 1 
ATOM   9781  N  N   . THR D 4 117 ? 117.431 139.344 143.308 1.00 152.34 ? 117 THR H N   1 
ATOM   9782  C  CA  . THR D 4 117 ? 117.143 140.615 142.664 1.00 147.41 ? 117 THR H CA  1 
ATOM   9783  C  C   . THR D 4 117 ? 117.946 140.744 141.369 1.00 170.40 ? 117 THR H C   1 
ATOM   9784  O  O   . THR D 4 117 ? 119.151 140.535 141.376 1.00 147.72 ? 117 THR H O   1 
ATOM   9785  C  CB  . THR D 4 117 ? 117.481 141.804 143.561 1.00 171.26 ? 117 THR H CB  1 
ATOM   9786  O  OG1 . THR D 4 117 ? 117.060 141.596 144.912 1.00 181.05 ? 117 THR H OG1 1 
ATOM   9787  C  CG2 . THR D 4 117 ? 116.841 143.055 142.994 1.00 219.39 ? 117 THR H CG2 1 
ATOM   9788  N  N   . VAL D 4 118 ? 117.290 141.103 140.260 1.00 169.59 ? 118 VAL H N   1 
ATOM   9789  C  CA  . VAL D 4 118 ? 117.973 141.222 138.973 1.00 169.95 ? 118 VAL H CA  1 
ATOM   9790  C  C   . VAL D 4 118 ? 118.022 142.703 138.600 1.00 210.68 ? 118 VAL H C   1 
ATOM   9791  O  O   . VAL D 4 118 ? 116.996 143.287 138.255 1.00 181.78 ? 118 VAL H O   1 
ATOM   9792  C  CB  . VAL D 4 118 ? 117.296 140.377 137.877 1.00 164.83 ? 118 VAL H CB  1 
ATOM   9793  C  CG1 . VAL D 4 118 ? 117.943 140.565 136.518 1.00 189.05 ? 118 VAL H CG1 1 
ATOM   9794  C  CG2 . VAL D 4 118 ? 117.297 138.908 138.218 1.00 166.16 ? 118 VAL H CG2 1 
ATOM   9795  N  N   . SER D 4 119 ? 119.228 143.297 138.678 1.00 229.85 ? 119 SER H N   1 
ATOM   9796  C  CA  . SER D 4 119 ? 119.430 144.727 138.483 1.00 260.24 ? 119 SER H CA  1 
ATOM   9797  C  C   . SER D 4 119 ? 120.893 145.022 138.175 1.00 242.46 ? 119 SER H C   1 
ATOM   9798  O  O   . SER D 4 119 ? 121.781 144.342 138.689 1.00 265.76 ? 119 SER H O   1 
ATOM   9799  C  CB  . SER D 4 119 ? 118.996 145.522 139.700 1.00 286.27 ? 119 SER H CB  1 
ATOM   9800  O  OG  . SER D 4 119 ? 119.232 146.914 139.521 1.00 268.60 ? 119 SER H OG  1 
ATOM   9801  N  N   . ALA D 4 120 ? 121.118 146.048 137.350 1.00 235.80 ? 120 ALA H N   1 
ATOM   9802  C  CA  . ALA D 4 120 ? 122.464 146.481 137.005 1.00 298.63 ? 120 ALA H CA  1 
ATOM   9803  C  C   . ALA D 4 120 ? 123.077 147.375 138.090 1.00 274.44 ? 120 ALA H C   1 
ATOM   9804  O  O   . ALA D 4 120 ? 124.307 147.487 138.140 1.00 308.89 ? 120 ALA H O   1 
ATOM   9805  C  CB  . ALA D 4 120 ? 122.428 147.182 135.666 1.00 384.42 ? 120 ALA H CB  1 
ATOM   9806  N  N   . ALA D 4 121 ? 122.232 148.009 138.933 1.00 250.52 ? 121 ALA H N   1 
ATOM   9807  C  CA  . ALA D 4 121 ? 122.681 148.879 140.013 1.00 241.74 ? 121 ALA H CA  1 
ATOM   9808  C  C   . ALA D 4 121 ? 123.501 148.079 141.029 1.00 241.56 ? 121 ALA H C   1 
ATOM   9809  O  O   . ALA D 4 121 ? 123.174 146.938 141.361 1.00 279.00 ? 121 ALA H O   1 
ATOM   9810  C  CB  . ALA D 4 121 ? 121.499 149.560 140.675 1.00 251.88 ? 121 ALA H CB  1 
ATOM   9811  N  N   . LYS D 4 122 ? 124.574 148.704 141.527 1.00 269.29 ? 122 LYS H N   1 
ATOM   9812  C  CA  . LYS D 4 122 ? 125.609 148.007 142.278 1.00 281.86 ? 122 LYS H CA  1 
ATOM   9813  C  C   . LYS D 4 122 ? 125.182 147.801 143.736 1.00 218.31 ? 122 LYS H C   1 
ATOM   9814  O  O   . LYS D 4 122 ? 124.414 148.583 144.313 1.00 183.89 ? 122 LYS H O   1 
ATOM   9815  C  CB  . LYS D 4 122 ? 126.943 148.766 142.183 1.00 352.05 ? 122 LYS H CB  1 
ATOM   9816  C  CG  . LYS D 4 122 ? 126.971 150.189 142.735 1.00 385.53 ? 122 LYS H CG  1 
ATOM   9817  C  CD  . LYS D 4 122 ? 128.348 150.806 142.687 1.00 396.25 ? 122 LYS H CD  1 
ATOM   9818  C  CE  . LYS D 4 122 ? 128.364 152.223 143.216 1.00 459.55 ? 122 LYS H CE  1 
ATOM   9819  N  NZ  . LYS D 4 122 ? 129.727 152.801 143.189 1.00 494.27 ? 122 LYS H NZ  1 
ATOM   9820  N  N   . THR D 4 123 ? 125.728 146.726 144.328 1.00 219.28 ? 123 THR H N   1 
ATOM   9821  C  CA  . THR D 4 123 ? 125.727 146.493 145.769 1.00 261.32 ? 123 THR H CA  1 
ATOM   9822  C  C   . THR D 4 123 ? 126.184 147.753 146.499 1.00 224.10 ? 123 THR H C   1 
ATOM   9823  O  O   . THR D 4 123 ? 127.174 148.367 146.095 1.00 251.13 ? 123 THR H O   1 
ATOM   9824  C  CB  . THR D 4 123 ? 126.643 145.321 146.160 1.00 306.12 ? 123 THR H CB  1 
ATOM   9825  O  OG1 . THR D 4 123 ? 126.221 144.163 145.433 1.00 369.19 ? 123 THR H OG1 1 
ATOM   9826  C  CG2 . THR D 4 123 ? 126.647 145.025 147.648 1.00 240.63 ? 123 THR H CG2 1 
ATOM   9827  N  N   . THR D 4 124 ? 125.450 148.123 147.555 1.00 219.64 ? 124 THR H N   1 
ATOM   9828  C  CA  . THR D 4 124 ? 125.685 149.372 148.258 1.00 244.64 ? 124 THR H CA  1 
ATOM   9829  C  C   . THR D 4 124 ? 125.427 149.127 149.743 1.00 246.89 ? 124 THR H C   1 
ATOM   9830  O  O   . THR D 4 124 ? 124.275 149.027 150.158 1.00 290.18 ? 124 THR H O   1 
ATOM   9831  C  CB  . THR D 4 124 ? 124.817 150.505 147.686 1.00 276.13 ? 124 THR H CB  1 
ATOM   9832  O  OG1 . THR D 4 124 ? 125.053 150.694 146.283 1.00 174.33 ? 124 THR H OG1 1 
ATOM   9833  C  CG2 . THR D 4 124 ? 125.078 151.823 148.390 1.00 294.71 ? 124 THR H CG2 1 
ATOM   9834  N  N   . PRO D 4 125 ? 126.465 149.016 150.598 1.00 244.33 ? 125 PRO H N   1 
ATOM   9835  C  CA  . PRO D 4 125 ? 126.244 148.835 152.031 1.00 229.53 ? 125 PRO H CA  1 
ATOM   9836  C  C   . PRO D 4 125 ? 125.415 149.948 152.675 1.00 272.55 ? 125 PRO H C   1 
ATOM   9837  O  O   . PRO D 4 125 ? 125.456 151.102 152.240 1.00 291.54 ? 125 PRO H O   1 
ATOM   9838  C  CB  . PRO D 4 125 ? 127.662 148.824 152.622 1.00 262.43 ? 125 PRO H CB  1 
ATOM   9839  C  CG  . PRO D 4 125 ? 128.534 148.402 151.475 1.00 321.19 ? 125 PRO H CG  1 
ATOM   9840  C  CD  . PRO D 4 125 ? 127.895 149.035 150.258 1.00 308.76 ? 125 PRO H CD  1 
ATOM   9841  N  N   . PRO D 4 126 ? 124.649 149.628 153.742 1.00 277.89 ? 126 PRO H N   1 
ATOM   9842  C  CA  . PRO D 4 126 ? 123.726 150.583 154.357 1.00 255.34 ? 126 PRO H CA  1 
ATOM   9843  C  C   . PRO D 4 126 ? 124.410 151.646 155.212 1.00 298.36 ? 126 PRO H C   1 
ATOM   9844  O  O   . PRO D 4 126 ? 125.474 151.408 155.784 1.00 351.45 ? 126 PRO H O   1 
ATOM   9845  C  CB  . PRO D 4 126 ? 122.835 149.692 155.242 1.00 259.85 ? 126 PRO H CB  1 
ATOM   9846  C  CG  . PRO D 4 126 ? 123.720 148.515 155.614 1.00 275.25 ? 126 PRO H CG  1 
ATOM   9847  C  CD  . PRO D 4 126 ? 124.635 148.326 154.425 1.00 272.36 ? 126 PRO H CD  1 
ATOM   9848  N  N   . SER D 4 127 ? 123.770 152.820 155.282 1.00 270.52 ? 127 SER H N   1 
ATOM   9849  C  CA  . SER D 4 127 ? 124.131 153.874 156.213 1.00 275.99 ? 127 SER H CA  1 
ATOM   9850  C  C   . SER D 4 127 ? 123.037 153.976 157.274 1.00 218.19 ? 127 SER H C   1 
ATOM   9851  O  O   . SER D 4 127 ? 121.871 154.161 156.934 1.00 252.79 ? 127 SER H O   1 
ATOM   9852  C  CB  . SER D 4 127 ? 124.329 155.180 155.484 1.00 338.25 ? 127 SER H CB  1 
ATOM   9853  O  OG  . SER D 4 127 ? 125.440 155.127 154.597 1.00 357.66 ? 127 SER H OG  1 
ATOM   9854  N  N   . ASP D 4 128 ? 123.420 153.855 158.558 1.00 237.79 ? 128 ASP H N   1 
ATOM   9855  C  CA  . ASP D 4 128 ? 122.490 153.733 159.681 1.00 243.93 ? 128 ASP H CA  1 
ATOM   9856  C  C   . ASP D 4 128 ? 122.534 155.002 160.525 1.00 246.93 ? 128 ASP H C   1 
ATOM   9857  O  O   . ASP D 4 128 ? 123.605 155.506 160.858 1.00 301.66 ? 128 ASP H O   1 
ATOM   9858  C  CB  . ASP D 4 128 ? 122.802 152.535 160.578 1.00 241.88 ? 128 ASP H CB  1 
ATOM   9859  C  CG  . ASP D 4 128 ? 123.309 151.357 159.769 1.00 292.38 ? 128 ASP H CG  1 
ATOM   9860  O  OD1 . ASP D 4 128 ? 122.583 150.931 158.860 1.00 343.71 ? 128 ASP H OD1 1 
ATOM   9861  O  OD2 . ASP D 4 128 ? 124.427 150.896 160.036 1.00 335.48 ? 128 ASP H OD2 1 
ATOM   9862  N  N   . TYR D 4 129 ? 121.356 155.506 160.876 1.00 233.49 ? 129 TYR H N   1 
ATOM   9863  C  CA  . TYR D 4 129 ? 121.238 156.791 161.539 1.00 247.15 ? 129 TYR H CA  1 
ATOM   9864  C  C   . TYR D 4 129 ? 120.213 156.657 162.658 1.00 271.82 ? 129 TYR H C   1 
ATOM   9865  O  O   . TYR D 4 129 ? 119.024 156.470 162.390 1.00 311.35 ? 129 TYR H O   1 
ATOM   9866  C  CB  . TYR D 4 129 ? 120.881 157.828 160.474 1.00 263.28 ? 129 TYR H CB  1 
ATOM   9867  C  CG  . TYR D 4 129 ? 121.993 158.111 159.475 1.00 253.61 ? 129 TYR H CG  1 
ATOM   9868  C  CD1 . TYR D 4 129 ? 123.255 158.517 159.905 1.00 285.49 ? 129 TYR H CD1 1 
ATOM   9869  C  CD2 . TYR D 4 129 ? 121.784 157.978 158.103 1.00 236.51 ? 129 TYR H CD2 1 
ATOM   9870  C  CE1 . TYR D 4 129 ? 124.275 158.781 159.001 1.00 339.16 ? 129 TYR H CE1 1 
ATOM   9871  C  CE2 . TYR D 4 129 ? 122.795 158.243 157.190 1.00 283.45 ? 129 TYR H CE2 1 
ATOM   9872  C  CZ  . TYR D 4 129 ? 124.046 158.645 157.640 1.00 346.70 ? 129 TYR H CZ  1 
ATOM   9873  O  OH  . TYR D 4 129 ? 125.064 158.910 156.764 1.00 369.09 ? 129 TYR H OH  1 
ATOM   9874  N  N   . PRO D 4 130 ? 120.641 156.738 163.939 1.00 276.80 ? 130 PRO H N   1 
ATOM   9875  C  CA  . PRO D 4 130 ? 119.733 156.547 165.067 1.00 281.26 ? 130 PRO H CA  1 
ATOM   9876  C  C   . PRO D 4 130 ? 118.850 157.768 165.307 1.00 279.51 ? 130 PRO H C   1 
ATOM   9877  O  O   . PRO D 4 130 ? 119.235 158.886 164.969 1.00 284.29 ? 130 PRO H O   1 
ATOM   9878  C  CB  . PRO D 4 130 ? 120.692 156.295 166.242 1.00 300.98 ? 130 PRO H CB  1 
ATOM   9879  C  CG  . PRO D 4 130 ? 121.929 157.088 165.881 1.00 325.91 ? 130 PRO H CG  1 
ATOM   9880  C  CD  . PRO D 4 130 ? 122.019 157.011 164.375 1.00 305.51 ? 130 PRO H CD  1 
ATOM   9881  N  N   . LEU D 4 131 ? 117.673 157.515 165.902 1.00 283.08 ? 131 LEU H N   1 
ATOM   9882  C  CA  . LEU D 4 131 ? 116.652 158.523 166.157 1.00 257.50 ? 131 LEU H CA  1 
ATOM   9883  C  C   . LEU D 4 131 ? 116.312 158.536 167.649 1.00 267.44 ? 131 LEU H C   1 
ATOM   9884  O  O   . LEU D 4 131 ? 115.954 157.498 168.209 1.00 254.15 ? 131 LEU H O   1 
ATOM   9885  C  CB  . LEU D 4 131 ? 115.416 158.187 165.320 1.00 226.19 ? 131 LEU H CB  1 
ATOM   9886  C  CG  . LEU D 4 131 ? 115.612 158.109 163.803 1.00 246.91 ? 131 LEU H CG  1 
ATOM   9887  C  CD1 . LEU D 4 131 ? 114.327 157.690 163.117 1.00 232.62 ? 131 LEU H CD1 1 
ATOM   9888  C  CD2 . LEU D 4 131 ? 116.077 159.429 163.213 1.00 299.50 ? 131 LEU H CD2 1 
ATOM   9889  N  N   . ALA D 4 132 ? 116.435 159.716 168.283 1.00 300.84 ? 132 ALA H N   1 
ATOM   9890  C  CA  . ALA D 4 132 ? 116.067 159.903 169.683 1.00 354.20 ? 132 ALA H CA  1 
ATOM   9891  C  C   . ALA D 4 132 ? 115.144 161.115 169.808 1.00 353.94 ? 132 ALA H C   1 
ATOM   9892  O  O   . ALA D 4 132 ? 115.321 162.085 169.067 1.00 342.11 ? 132 ALA H O   1 
ATOM   9893  C  CB  . ALA D 4 132 ? 117.295 160.049 170.553 1.00 402.97 ? 132 ALA H CB  1 
ATOM   9894  N  N   . PRO D 4 133 ? 114.143 161.096 170.731 1.00 366.25 ? 133 PRO H N   1 
ATOM   9895  C  CA  . PRO D 4 133 ? 113.021 162.047 170.677 1.00 414.57 ? 133 PRO H CA  1 
ATOM   9896  C  C   . PRO D 4 133 ? 113.306 163.550 170.805 1.00 437.65 ? 133 PRO H C   1 
ATOM   9897  O  O   . PRO D 4 133 ? 112.510 164.341 170.299 1.00 461.14 ? 133 PRO H O   1 
ATOM   9898  C  CB  . PRO D 4 133 ? 112.138 161.623 171.872 1.00 432.25 ? 133 PRO H CB  1 
ATOM   9899  C  CG  . PRO D 4 133 ? 112.520 160.187 172.135 1.00 402.49 ? 133 PRO H CG  1 
ATOM   9900  C  CD  . PRO D 4 133 ? 114.007 160.159 171.867 1.00 354.09 ? 133 PRO H CD  1 
ATOM   9901  N  N   . GLY D 4 134 ? 114.407 163.949 171.471 1.00 443.83 ? 134 GLY H N   1 
ATOM   9902  C  CA  . GLY D 4 134 ? 114.767 165.356 171.632 1.00 476.97 ? 134 GLY H CA  1 
ATOM   9903  C  C   . GLY D 4 134 ? 113.976 166.052 172.745 1.00 491.30 ? 134 GLY H C   1 
ATOM   9904  O  O   . GLY D 4 134 ? 114.053 165.622 173.895 1.00 440.11 ? 134 GLY H O   1 
ATOM   9905  N  N   . SER D 4 135 ? 113.229 167.125 172.400 1.00 520.18 ? 135 SER H N   1 
ATOM   9906  C  CA  . SER D 4 135 ? 112.445 167.923 173.341 1.00 521.07 ? 135 SER H CA  1 
ATOM   9907  C  C   . SER D 4 135 ? 111.323 167.106 173.996 1.00 546.24 ? 135 SER H C   1 
ATOM   9908  O  O   . SER D 4 135 ? 110.665 166.313 173.321 1.00 568.70 ? 135 SER H O   1 
ATOM   9909  C  CB  . SER D 4 135 ? 111.860 169.146 172.660 1.00 478.67 ? 135 SER H CB  1 
ATOM   9910  O  OG  . SER D 4 135 ? 112.868 169.974 172.092 1.00 420.37 ? 135 SER H OG  1 
ATOM   9911  N  N   . ALA D 4 136 ? 111.119 167.316 175.314 1.00 533.98 ? 136 ALA H N   1 
ATOM   9912  C  CA  . ALA D 4 136 ? 110.034 166.747 176.118 1.00 508.62 ? 136 ALA H CA  1 
ATOM   9913  C  C   . ALA D 4 136 ? 109.986 165.209 176.089 1.00 529.02 ? 136 ALA H C   1 
ATOM   9914  O  O   . ALA D 4 136 ? 108.908 164.624 176.248 1.00 509.95 ? 136 ALA H O   1 
ATOM   9915  C  CB  . ALA D 4 136 ? 108.716 167.361 175.684 1.00 497.61 ? 136 ALA H CB  1 
ATOM   9916  N  N   . ALA D 4 137 ? 111.151 164.558 175.919 1.00 588.93 ? 137 ALA H N   1 
ATOM   9917  C  CA  . ALA D 4 137 ? 111.248 163.112 175.729 1.00 628.83 ? 137 ALA H CA  1 
ATOM   9918  C  C   . ALA D 4 137 ? 110.708 162.343 176.938 1.00 607.69 ? 137 ALA H C   1 
ATOM   9919  O  O   . ALA D 4 137 ? 109.857 161.465 176.780 1.00 574.66 ? 137 ALA H O   1 
ATOM   9920  C  CB  . ALA D 4 137 ? 112.685 162.732 175.455 1.00 659.82 ? 137 ALA H CB  1 
ATOM   9921  N  N   . GLN D 4 138 ? 111.201 162.692 178.139 1.00 599.36 ? 138 GLN H N   1 
ATOM   9922  C  CA  . GLN D 4 138 ? 110.899 161.976 179.376 1.00 593.30 ? 138 GLN H CA  1 
ATOM   9923  C  C   . GLN D 4 138 ? 109.587 162.440 180.030 1.00 602.82 ? 138 GLN H C   1 
ATOM   9924  O  O   . GLN D 4 138 ? 109.259 161.954 181.113 1.00 612.16 ? 138 GLN H O   1 
ATOM   9925  C  CB  . GLN D 4 138 ? 112.074 162.126 180.354 1.00 571.29 ? 138 GLN H CB  1 
ATOM   9926  C  CG  . GLN D 4 138 ? 113.365 161.458 179.887 1.00 546.48 ? 138 GLN H CG  1 
ATOM   9927  C  CD  . GLN D 4 138 ? 113.306 159.950 179.957 1.00 528.53 ? 138 GLN H CD  1 
ATOM   9928  O  OE1 . GLN D 4 138 ? 112.958 159.283 178.985 1.00 546.23 ? 138 GLN H OE1 1 
ATOM   9929  N  NE2 . GLN D 4 138 ? 113.642 159.395 181.113 1.00 487.83 ? 138 GLN H NE2 1 
ATOM   9930  N  N   . THR D 4 139 ? 108.826 163.353 179.392 1.00 591.32 ? 139 THR H N   1 
ATOM   9931  C  CA  . THR D 4 139 ? 107.534 163.822 179.892 1.00 562.74 ? 139 THR H CA  1 
ATOM   9932  C  C   . THR D 4 139 ? 106.447 162.731 179.822 1.00 505.96 ? 139 THR H C   1 
ATOM   9933  O  O   . THR D 4 139 ? 105.380 162.912 180.413 1.00 520.27 ? 139 THR H O   1 
ATOM   9934  C  CB  . THR D 4 139 ? 107.125 165.115 179.155 1.00 549.11 ? 139 THR H CB  1 
ATOM   9935  O  OG1 . THR D 4 139 ? 108.210 166.045 179.194 1.00 508.89 ? 139 THR H OG1 1 
ATOM   9936  C  CG2 . THR D 4 139 ? 105.905 165.799 179.737 1.00 537.56 ? 139 THR H CG2 1 
ATOM   9937  N  N   . ASN D 4 140 ? 106.698 161.604 179.118 1.00 422.77 ? 140 ASN H N   1 
ATOM   9938  C  CA  . ASN D 4 140 ? 105.763 160.487 179.016 1.00 388.81 ? 140 ASN H CA  1 
ATOM   9939  C  C   . ASN D 4 140 ? 106.399 159.194 179.549 1.00 367.81 ? 140 ASN H C   1 
ATOM   9940  O  O   . ASN D 4 140 ? 107.619 159.029 179.524 1.00 392.36 ? 140 ASN H O   1 
ATOM   9941  C  CB  . ASN D 4 140 ? 105.278 160.323 177.569 1.00 409.13 ? 140 ASN H CB  1 
ATOM   9942  C  CG  . ASN D 4 140 ? 104.564 161.521 176.968 1.00 441.35 ? 140 ASN H CG  1 
ATOM   9943  O  OD1 . ASN D 4 140 ? 104.494 161.642 175.746 1.00 433.91 ? 140 ASN H OD1 1 
ATOM   9944  N  ND2 . ASN D 4 140 ? 104.028 162.409 177.790 1.00 461.87 ? 140 ASN H ND2 1 
ATOM   9945  N  N   . SER D 4 141 ? 105.550 158.267 180.028 1.00 376.20 ? 141 SER H N   1 
ATOM   9946  C  CA  . SER D 4 141 ? 105.980 157.075 180.757 1.00 393.13 ? 141 SER H CA  1 
ATOM   9947  C  C   . SER D 4 141 ? 106.680 156.046 179.859 1.00 409.60 ? 141 SER H C   1 
ATOM   9948  O  O   . SER D 4 141 ? 107.591 155.363 180.332 1.00 403.24 ? 141 SER H O   1 
ATOM   9949  C  CB  . SER D 4 141 ? 104.811 156.450 181.484 1.00 382.20 ? 141 SER H CB  1 
ATOM   9950  O  OG  . SER D 4 141 ? 103.776 156.100 180.576 1.00 399.69 ? 141 SER H OG  1 
ATOM   9951  N  N   . MET D 4 142 ? 106.245 155.937 178.587 1.00 388.61 ? 142 MET H N   1 
ATOM   9952  C  CA  . MET D 4 142 ? 106.870 155.096 177.567 1.00 329.86 ? 142 MET H CA  1 
ATOM   9953  C  C   . MET D 4 142 ? 107.485 155.976 176.476 1.00 294.43 ? 142 MET H C   1 
ATOM   9954  O  O   . MET D 4 142 ? 106.867 156.957 176.066 1.00 223.35 ? 142 MET H O   1 
ATOM   9955  C  CB  . MET D 4 142 ? 105.827 154.167 176.935 1.00 332.67 ? 142 MET H CB  1 
ATOM   9956  C  CG  . MET D 4 142 ? 105.369 153.050 177.857 1.00 354.81 ? 142 MET H CG  1 
ATOM   9957  S  SD  . MET D 4 142 ? 106.633 151.784 178.149 1.00 364.27 ? 142 MET H SD  1 
ATOM   9958  C  CE  . MET D 4 142 ? 105.621 150.444 178.777 1.00 382.24 ? 142 MET H CE  1 
ATOM   9959  N  N   . VAL D 4 143 ? 108.698 155.618 176.008 1.00 326.99 ? 143 VAL H N   1 
ATOM   9960  C  CA  . VAL D 4 143 ? 109.448 156.420 175.042 1.00 337.82 ? 143 VAL H CA  1 
ATOM   9961  C  C   . VAL D 4 143 ? 109.856 155.555 173.850 1.00 313.81 ? 143 VAL H C   1 
ATOM   9962  O  O   . VAL D 4 143 ? 110.332 154.427 174.018 1.00 261.06 ? 143 VAL H O   1 
ATOM   9963  C  CB  . VAL D 4 143 ? 110.679 157.106 175.669 1.00 365.84 ? 143 VAL H CB  1 
ATOM   9964  C  CG1 . VAL D 4 143 ? 110.250 158.156 176.681 1.00 389.95 ? 143 VAL H CG1 1 
ATOM   9965  C  CG2 . VAL D 4 143 ? 111.676 156.132 176.298 1.00 379.89 ? 143 VAL H CG2 1 
ATOM   9966  N  N   . THR D 4 144 ? 109.666 156.121 172.645 1.00 299.73 ? 144 THR H N   1 
ATOM   9967  C  CA  . THR D 4 144 ? 109.962 155.440 171.394 1.00 307.85 ? 144 THR H CA  1 
ATOM   9968  C  C   . THR D 4 144 ? 111.369 155.824 170.934 1.00 281.79 ? 144 THR H C   1 
ATOM   9969  O  O   . THR D 4 144 ? 111.794 156.963 171.121 1.00 249.42 ? 144 THR H O   1 
ATOM   9970  C  CB  . THR D 4 144 ? 108.909 155.754 170.321 1.00 318.22 ? 144 THR H CB  1 
ATOM   9971  O  OG1 . THR D 4 144 ? 107.615 155.408 170.816 1.00 329.75 ? 144 THR H OG1 1 
ATOM   9972  C  CG2 . THR D 4 144 ? 109.121 155.004 169.023 1.00 335.66 ? 144 THR H CG2 1 
ATOM   9973  N  N   . LEU D 4 145 ? 112.066 154.850 170.324 1.00 292.07 ? 145 LEU H N   1 
ATOM   9974  C  CA  . LEU D 4 145 ? 113.399 155.013 169.760 1.00 273.83 ? 145 LEU H CA  1 
ATOM   9975  C  C   . LEU D 4 145 ? 113.416 154.432 168.347 1.00 259.85 ? 145 LEU H C   1 
ATOM   9976  O  O   . LEU D 4 145 ? 112.628 153.550 168.017 1.00 213.78 ? 145 LEU H O   1 
ATOM   9977  C  CB  . LEU D 4 145 ? 114.407 154.284 170.647 1.00 280.83 ? 145 LEU H CB  1 
ATOM   9978  C  CG  . LEU D 4 145 ? 114.397 154.651 172.130 1.00 357.98 ? 145 LEU H CG  1 
ATOM   9979  C  CD1 . LEU D 4 145 ? 115.295 153.704 172.897 1.00 412.95 ? 145 LEU H CD1 1 
ATOM   9980  C  CD2 . LEU D 4 145 ? 114.843 156.090 172.367 1.00 401.61 ? 145 LEU H CD2 1 
ATOM   9981  N  N   . GLY D 4 146 ? 114.325 154.928 167.504 1.00 257.10 ? 146 GLY H N   1 
ATOM   9982  C  CA  . GLY D 4 146 ? 114.293 154.575 166.094 1.00 234.25 ? 146 GLY H CA  1 
ATOM   9983  C  C   . GLY D 4 146 ? 115.670 154.498 165.448 1.00 216.71 ? 146 GLY H C   1 
ATOM   9984  O  O   . GLY D 4 146 ? 116.679 154.912 166.017 1.00 250.80 ? 146 GLY H O   1 
ATOM   9985  N  N   . CYS D 4 147 ? 115.668 153.961 164.231 1.00 193.59 ? 147 CYS H N   1 
ATOM   9986  C  CA  . CYS D 4 147 ? 116.876 153.679 163.483 1.00 190.80 ? 147 CYS H CA  1 
ATOM   9987  C  C   . CYS D 4 147 ? 116.505 153.770 162.011 1.00 178.70 ? 147 CYS H C   1 
ATOM   9988  O  O   . CYS D 4 147 ? 115.884 152.843 161.490 1.00 212.94 ? 147 CYS H O   1 
ATOM   9989  C  CB  . CYS D 4 147 ? 117.391 152.300 163.892 1.00 218.46 ? 147 CYS H CB  1 
ATOM   9990  S  SG  . CYS D 4 147 ? 118.954 151.766 163.138 1.00 288.32 ? 147 CYS H SG  1 
ATOM   9991  N  N   . LEU D 4 148 ? 116.863 154.894 161.372 1.00 149.38 ? 148 LEU H N   1 
ATOM   9992  C  CA  . LEU D 4 148 ? 116.799 155.003 159.921 1.00 203.29 ? 148 LEU H CA  1 
ATOM   9993  C  C   . LEU D 4 148 ? 117.948 154.203 159.276 1.00 194.25 ? 148 LEU H C   1 
ATOM   9994  O  O   . LEU D 4 148 ? 119.083 154.259 159.743 1.00 195.83 ? 148 LEU H O   1 
ATOM   9995  C  CB  . LEU D 4 148 ? 116.847 156.486 159.521 1.00 190.44 ? 148 LEU H CB  1 
ATOM   9996  C  CG  . LEU D 4 148 ? 116.954 156.774 158.015 1.00 222.46 ? 148 LEU H CG  1 
ATOM   9997  C  CD1 . LEU D 4 148 ? 115.656 156.461 157.293 1.00 229.17 ? 148 LEU H CD1 1 
ATOM   9998  C  CD2 . LEU D 4 148 ? 117.351 158.212 157.759 1.00 266.21 ? 148 LEU H CD2 1 
ATOM   9999  N  N   . VAL D 4 149 ? 117.631 153.472 158.194 1.00 190.64 ? 149 VAL H N   1 
ATOM   10000 C  CA  . VAL D 4 149 ? 118.566 152.742 157.359 1.00 186.35 ? 149 VAL H CA  1 
ATOM   10001 C  C   . VAL D 4 149 ? 118.413 153.290 155.941 1.00 207.03 ? 149 VAL H C   1 
ATOM   10002 O  O   . VAL D 4 149 ? 117.347 153.173 155.349 1.00 201.19 ? 149 VAL H O   1 
ATOM   10003 C  CB  . VAL D 4 149 ? 118.267 151.228 157.417 1.00 192.80 ? 149 VAL H CB  1 
ATOM   10004 C  CG1 . VAL D 4 149 ? 119.213 150.426 156.525 1.00 196.83 ? 149 VAL H CG1 1 
ATOM   10005 C  CG2 . VAL D 4 149 ? 118.260 150.697 158.857 1.00 160.45 ? 149 VAL H CG2 1 
ATOM   10006 N  N   . LYS D 4 150 ? 119.469 153.879 155.375 1.00 252.51 ? 150 LYS H N   1 
ATOM   10007 C  CA  . LYS D 4 150 ? 119.306 154.724 154.198 1.00 254.09 ? 150 LYS H CA  1 
ATOM   10008 C  C   . LYS D 4 150 ? 120.260 154.296 153.074 1.00 277.84 ? 150 LYS H C   1 
ATOM   10009 O  O   . LYS D 4 150 ? 121.368 153.820 153.313 1.00 259.82 ? 150 LYS H O   1 
ATOM   10010 C  CB  . LYS D 4 150 ? 119.474 156.175 154.653 1.00 236.08 ? 150 LYS H CB  1 
ATOM   10011 C  CG  . LYS D 4 150 ? 119.415 157.229 153.563 1.00 286.69 ? 150 LYS H CG  1 
ATOM   10012 C  CD  . LYS D 4 150 ? 119.606 158.630 154.123 1.00 313.39 ? 150 LYS H CD  1 
ATOM   10013 C  CE  . LYS D 4 150 ? 119.849 159.677 153.054 1.00 362.09 ? 150 LYS H CE  1 
ATOM   10014 N  NZ  . LYS D 4 150 ? 118.756 159.726 152.049 1.00 405.87 ? 150 LYS H NZ  1 
ATOM   10015 N  N   . GLY D 4 151 ? 119.790 154.478 151.830 1.00 270.69 ? 151 GLY H N   1 
ATOM   10016 C  CA  . GLY D 4 151 ? 120.602 154.377 150.623 1.00 275.95 ? 151 GLY H CA  1 
ATOM   10017 C  C   . GLY D 4 151 ? 121.287 153.030 150.372 1.00 255.79 ? 151 GLY H C   1 
ATOM   10018 O  O   . GLY D 4 151 ? 122.275 152.989 149.638 1.00 298.01 ? 151 GLY H O   1 
ATOM   10019 N  N   . TYR D 4 152 ? 120.768 151.939 150.949 1.00 228.27 ? 152 TYR H N   1 
ATOM   10020 C  CA  . TYR D 4 152 ? 121.397 150.623 150.870 1.00 219.70 ? 152 TYR H CA  1 
ATOM   10021 C  C   . TYR D 4 152 ? 120.898 149.828 149.654 1.00 214.19 ? 152 TYR H C   1 
ATOM   10022 O  O   . TYR D 4 152 ? 119.934 150.227 149.012 1.00 171.18 ? 152 TYR H O   1 
ATOM   10023 C  CB  . TYR D 4 152 ? 121.120 149.899 152.191 1.00 206.60 ? 152 TYR H CB  1 
ATOM   10024 C  CG  . TYR D 4 152 ? 119.759 149.248 152.367 1.00 200.85 ? 152 TYR H CG  1 
ATOM   10025 C  CD1 . TYR D 4 152 ? 118.652 149.962 152.821 1.00 210.71 ? 152 TYR H CD1 1 
ATOM   10026 C  CD2 . TYR D 4 152 ? 119.586 147.911 152.064 1.00 175.08 ? 152 TYR H CD2 1 
ATOM   10027 C  CE1 . TYR D 4 152 ? 117.412 149.362 152.974 1.00 177.41 ? 152 TYR H CE1 1 
ATOM   10028 C  CE2 . TYR D 4 152 ? 118.355 147.303 152.211 1.00 227.24 ? 152 TYR H CE2 1 
ATOM   10029 C  CZ  . TYR D 4 152 ? 117.263 148.024 152.663 1.00 199.62 ? 152 TYR H CZ  1 
ATOM   10030 O  OH  . TYR D 4 152 ? 116.074 147.369 152.795 1.00 232.79 ? 152 TYR H OH  1 
ATOM   10031 N  N   . PHE D 4 153 ? 121.562 148.695 149.344 1.00 212.80 ? 153 PHE H N   1 
ATOM   10032 C  CA  . PHE D 4 153 ? 121.138 147.766 148.294 1.00 174.46 ? 153 PHE H CA  1 
ATOM   10033 C  C   . PHE D 4 153 ? 121.866 146.431 148.437 1.00 167.27 ? 153 PHE H C   1 
ATOM   10034 O  O   . PHE D 4 153 ? 123.005 146.446 148.918 1.00 173.90 ? 153 PHE H O   1 
ATOM   10035 C  CB  . PHE D 4 153 ? 121.471 148.372 146.936 1.00 138.91 ? 153 PHE H CB  1 
ATOM   10036 C  CG  . PHE D 4 153 ? 120.736 147.779 145.773 1.00 141.02 ? 153 PHE H CG  1 
ATOM   10037 C  CD1 . PHE D 4 153 ? 121.181 146.634 145.135 1.00 145.72 ? 153 PHE H CD1 1 
ATOM   10038 C  CD2 . PHE D 4 153 ? 119.593 148.395 145.295 1.00 180.27 ? 153 PHE H CD2 1 
ATOM   10039 C  CE1 . PHE D 4 153 ? 120.480 146.120 144.049 1.00 194.14 ? 153 PHE H CE1 1 
ATOM   10040 C  CE2 . PHE D 4 153 ? 118.894 147.884 144.205 1.00 204.38 ? 153 PHE H CE2 1 
ATOM   10041 C  CZ  . PHE D 4 153 ? 119.335 146.741 143.579 1.00 194.11 ? 153 PHE H CZ  1 
ATOM   10042 N  N   . PRO D 4 154 ? 121.310 145.246 148.058 1.00 166.77 ? 154 PRO H N   1 
ATOM   10043 C  CA  . PRO D 4 154 ? 119.929 145.012 147.641 1.00 195.10 ? 154 PRO H CA  1 
ATOM   10044 C  C   . PRO D 4 154 ? 118.941 144.952 148.802 1.00 226.14 ? 154 PRO H C   1 
ATOM   10045 O  O   . PRO D 4 154 ? 119.294 145.277 149.927 1.00 206.26 ? 154 PRO H O   1 
ATOM   10046 C  CB  . PRO D 4 154 ? 119.985 143.635 146.949 1.00 212.88 ? 154 PRO H CB  1 
ATOM   10047 C  CG  . PRO D 4 154 ? 121.439 143.294 146.829 1.00 246.84 ? 154 PRO H CG  1 
ATOM   10048 C  CD  . PRO D 4 154 ? 122.038 143.981 148.026 1.00 231.68 ? 154 PRO H CD  1 
ATOM   10049 N  N   . GLU D 4 155 ? 117.703 144.516 148.488 1.00 231.01 ? 155 GLU H N   1 
ATOM   10050 C  CA  . GLU D 4 155 ? 116.502 144.601 149.320 1.00 224.90 ? 155 GLU H CA  1 
ATOM   10051 C  C   . GLU D 4 155 ? 116.650 144.114 150.768 1.00 247.46 ? 155 GLU H C   1 
ATOM   10052 O  O   . GLU D 4 155 ? 116.198 144.830 151.666 1.00 271.13 ? 155 GLU H O   1 
ATOM   10053 C  CB  . GLU D 4 155 ? 115.381 143.822 148.624 1.00 219.93 ? 155 GLU H CB  1 
ATOM   10054 C  CG  . GLU D 4 155 ? 114.122 143.554 149.459 1.00 323.73 ? 155 GLU H CG  1 
ATOM   10055 C  CD  . GLU D 4 155 ? 113.371 144.743 150.061 1.00 359.97 ? 155 GLU H CD  1 
ATOM   10056 O  OE1 . GLU D 4 155 ? 113.343 145.820 149.436 1.00 347.32 ? 155 GLU H OE1 1 
ATOM   10057 O  OE2 . GLU D 4 155 ? 112.783 144.581 151.161 1.00 417.46 ? 155 GLU H OE2 1 
ATOM   10058 N  N   . PRO D 4 156 ? 117.231 142.925 151.076 1.00 216.43 ? 156 PRO H N   1 
ATOM   10059 C  CA  . PRO D 4 156 ? 117.109 142.347 152.422 1.00 192.61 ? 156 PRO H CA  1 
ATOM   10060 C  C   . PRO D 4 156 ? 118.129 142.935 153.389 1.00 197.62 ? 156 PRO H C   1 
ATOM   10061 O  O   . PRO D 4 156 ? 119.328 142.648 153.297 1.00 184.51 ? 156 PRO H O   1 
ATOM   10062 C  CB  . PRO D 4 156 ? 117.398 140.865 152.221 1.00 220.57 ? 156 PRO H CB  1 
ATOM   10063 C  CG  . PRO D 4 156 ? 118.344 140.850 151.010 1.00 264.75 ? 156 PRO H CG  1 
ATOM   10064 C  CD  . PRO D 4 156 ? 118.047 142.085 150.182 1.00 202.27 ? 156 PRO H CD  1 
ATOM   10065 N  N   . VAL D 4 157 ? 117.616 143.783 154.291 1.00 215.41 ? 157 VAL H N   1 
ATOM   10066 C  CA  . VAL D 4 157 ? 118.332 144.219 155.479 1.00 220.24 ? 157 VAL H CA  1 
ATOM   10067 C  C   . VAL D 4 157 ? 117.455 143.841 156.661 1.00 204.04 ? 157 VAL H C   1 
ATOM   10068 O  O   . VAL D 4 157 ? 116.230 143.903 156.574 1.00 232.24 ? 157 VAL H O   1 
ATOM   10069 C  CB  . VAL D 4 157 ? 118.717 145.720 155.473 1.00 211.90 ? 157 VAL H CB  1 
ATOM   10070 C  CG1 . VAL D 4 157 ? 117.552 146.662 155.729 1.00 195.62 ? 157 VAL H CG1 1 
ATOM   10071 C  CG2 . VAL D 4 157 ? 119.841 146.021 156.456 1.00 225.08 ? 157 VAL H CG2 1 
ATOM   10072 N  N   . THR D 4 158 ? 118.115 143.437 157.747 1.00 206.04 ? 158 THR H N   1 
ATOM   10073 C  CA  . THR D 4 158 ? 117.438 142.919 158.919 1.00 237.85 ? 158 THR H CA  1 
ATOM   10074 C  C   . THR D 4 158 ? 117.777 143.833 160.088 1.00 239.15 ? 158 THR H C   1 
ATOM   10075 O  O   . THR D 4 158 ? 118.900 144.321 160.175 1.00 267.08 ? 158 THR H O   1 
ATOM   10076 C  CB  . THR D 4 158 ? 117.841 141.461 159.175 1.00 283.90 ? 158 THR H CB  1 
ATOM   10077 O  OG1 . THR D 4 158 ? 117.781 140.729 157.946 1.00 258.09 ? 158 THR H OG1 1 
ATOM   10078 C  CG2 . THR D 4 158 ? 116.965 140.801 160.220 1.00 319.93 ? 158 THR H CG2 1 
ATOM   10079 N  N   . VAL D 4 159 ? 116.803 144.059 160.976 1.00 222.63 ? 159 VAL H N   1 
ATOM   10080 C  CA  . VAL D 4 159 ? 117.052 144.800 162.205 1.00 224.73 ? 159 VAL H CA  1 
ATOM   10081 C  C   . VAL D 4 159 ? 116.514 143.979 163.371 1.00 226.06 ? 159 VAL H C   1 
ATOM   10082 O  O   . VAL D 4 159 ? 115.408 143.437 163.314 1.00 236.91 ? 159 VAL H O   1 
ATOM   10083 C  CB  . VAL D 4 159 ? 116.438 146.217 162.188 1.00 217.90 ? 159 VAL H CB  1 
ATOM   10084 C  CG1 . VAL D 4 159 ? 116.799 146.991 163.446 1.00 155.73 ? 159 VAL H CG1 1 
ATOM   10085 C  CG2 . VAL D 4 159 ? 116.818 146.998 160.928 1.00 220.84 ? 159 VAL H CG2 1 
ATOM   10086 N  N   . THR D 4 160 ? 117.338 143.904 164.419 1.00 254.09 ? 160 THR H N   1 
ATOM   10087 C  CA  . THR D 4 160 ? 116.939 143.441 165.736 1.00 315.31 ? 160 THR H CA  1 
ATOM   10088 C  C   . THR D 4 160 ? 117.536 144.406 166.751 1.00 281.32 ? 160 THR H C   1 
ATOM   10089 O  O   . THR D 4 160 ? 118.581 144.997 166.499 1.00 233.03 ? 160 THR H O   1 
ATOM   10090 C  CB  . THR D 4 160 ? 117.374 141.992 166.007 1.00 415.27 ? 160 THR H CB  1 
ATOM   10091 O  OG1 . THR D 4 160 ? 118.797 141.873 165.955 1.00 420.22 ? 160 THR H OG1 1 
ATOM   10092 C  CG2 . THR D 4 160 ? 116.784 140.999 165.029 1.00 473.11 ? 160 THR H CG2 1 
ATOM   10093 N  N   . TRP D 4 161 ? 116.863 144.550 167.893 1.00 295.89 ? 161 TRP H N   1 
ATOM   10094 C  CA  . TRP D 4 161 ? 117.271 145.505 168.906 1.00 304.43 ? 161 TRP H CA  1 
ATOM   10095 C  C   . TRP D 4 161 ? 117.873 144.787 170.119 1.00 341.57 ? 161 TRP H C   1 
ATOM   10096 O  O   . TRP D 4 161 ? 117.293 143.820 170.614 1.00 344.75 ? 161 TRP H O   1 
ATOM   10097 C  CB  . TRP D 4 161 ? 116.064 146.369 169.273 1.00 271.38 ? 161 TRP H CB  1 
ATOM   10098 C  CG  . TRP D 4 161 ? 115.644 147.345 168.201 1.00 239.56 ? 161 TRP H CG  1 
ATOM   10099 C  CD1 . TRP D 4 161 ? 114.789 147.129 167.158 1.00 257.27 ? 161 TRP H CD1 1 
ATOM   10100 C  CD2 . TRP D 4 161 ? 116.070 148.722 168.085 1.00 201.25 ? 161 TRP H CD2 1 
ATOM   10101 N  NE1 . TRP D 4 161 ? 114.643 148.272 166.412 1.00 268.67 ? 161 TRP H NE1 1 
ATOM   10102 C  CE2 . TRP D 4 161 ? 115.421 149.265 166.949 1.00 227.29 ? 161 TRP H CE2 1 
ATOM   10103 C  CE3 . TRP D 4 161 ? 116.927 149.544 168.829 1.00 227.41 ? 161 TRP H CE3 1 
ATOM   10104 C  CZ2 . TRP D 4 161 ? 115.605 150.591 166.544 1.00 203.85 ? 161 TRP H CZ2 1 
ATOM   10105 C  CZ3 . TRP D 4 161 ? 117.113 150.850 168.427 1.00 268.12 ? 161 TRP H CZ3 1 
ATOM   10106 C  CH2 . TRP D 4 161 ? 116.457 151.364 167.303 1.00 219.85 ? 161 TRP H CH2 1 
ATOM   10107 N  N   . ASN D 4 162 ? 119.044 145.271 170.584 1.00 336.07 ? 162 ASN H N   1 
ATOM   10108 C  CA  . ASN D 4 162 ? 119.824 144.672 171.665 1.00 312.82 ? 162 ASN H CA  1 
ATOM   10109 C  C   . ASN D 4 162 ? 120.024 143.172 171.421 1.00 329.68 ? 162 ASN H C   1 
ATOM   10110 O  O   . ASN D 4 162 ? 119.705 142.355 172.284 1.00 329.33 ? 162 ASN H O   1 
ATOM   10111 C  CB  . ASN D 4 162 ? 119.200 145.002 173.032 1.00 297.84 ? 162 ASN H CB  1 
ATOM   10112 C  CG  . ASN D 4 162 ? 119.458 146.420 173.500 1.00 288.66 ? 162 ASN H CG  1 
ATOM   10113 O  OD1 . ASN D 4 162 ? 119.998 147.234 172.759 1.00 238.38 ? 162 ASN H OD1 1 
ATOM   10114 N  ND2 . ASN D 4 162 ? 119.082 146.728 174.733 1.00 279.55 ? 162 ASN H ND2 1 
ATOM   10115 N  N   . SER D 4 163 ? 120.546 142.822 170.231 1.00 328.55 ? 163 SER H N   1 
ATOM   10116 C  CA  . SER D 4 163 ? 120.895 141.454 169.852 1.00 350.98 ? 163 SER H CA  1 
ATOM   10117 C  C   . SER D 4 163 ? 119.703 140.488 169.959 1.00 308.08 ? 163 SER H C   1 
ATOM   10118 O  O   . SER D 4 163 ? 119.874 139.320 170.311 1.00 267.64 ? 163 SER H O   1 
ATOM   10119 C  CB  . SER D 4 163 ? 122.082 140.963 170.672 1.00 432.02 ? 163 SER H CB  1 
ATOM   10120 O  OG  . SER D 4 163 ? 123.165 141.887 170.648 1.00 456.63 ? 163 SER H OG  1 
ATOM   10121 N  N   . GLY D 4 164 ? 118.489 140.972 169.657 1.00 357.27 ? 164 GLY H N   1 
ATOM   10122 C  CA  . GLY D 4 164 ? 117.270 140.175 169.733 1.00 390.00 ? 164 GLY H CA  1 
ATOM   10123 C  C   . GLY D 4 164 ? 116.614 140.124 171.119 1.00 414.08 ? 164 GLY H C   1 
ATOM   10124 O  O   . GLY D 4 164 ? 115.570 139.485 171.255 1.00 431.41 ? 164 GLY H O   1 
ATOM   10125 N  N   . SER D 4 165 ? 117.203 140.787 172.133 1.00 401.81 ? 165 SER H N   1 
ATOM   10126 C  CA  . SER D 4 165 ? 116.661 140.821 173.488 1.00 385.55 ? 165 SER H CA  1 
ATOM   10127 C  C   . SER D 4 165 ? 115.348 141.607 173.546 1.00 391.98 ? 165 SER H C   1 
ATOM   10128 O  O   . SER D 4 165 ? 114.417 141.182 174.233 1.00 384.04 ? 165 SER H O   1 
ATOM   10129 C  CB  . SER D 4 165 ? 117.662 141.389 174.471 1.00 361.03 ? 165 SER H CB  1 
ATOM   10130 O  OG  . SER D 4 165 ? 118.924 140.751 174.347 1.00 362.48 ? 165 SER H OG  1 
ATOM   10131 N  N   . LEU D 4 166 ? 115.276 142.740 172.824 1.00 366.49 ? 166 LEU H N   1 
ATOM   10132 C  CA  . LEU D 4 166 ? 114.070 143.561 172.749 1.00 341.07 ? 166 LEU H CA  1 
ATOM   10133 C  C   . LEU D 4 166 ? 113.179 143.105 171.588 1.00 349.21 ? 166 LEU H C   1 
ATOM   10134 O  O   . LEU D 4 166 ? 112.818 143.906 170.725 1.00 338.30 ? 166 LEU H O   1 
ATOM   10135 C  CB  . LEU D 4 166 ? 114.478 145.037 172.612 1.00 302.85 ? 166 LEU H CB  1 
ATOM   10136 C  CG  . LEU D 4 166 ? 115.153 145.669 173.831 1.00 326.41 ? 166 LEU H CG  1 
ATOM   10137 C  CD1 . LEU D 4 166 ? 115.493 147.127 173.572 1.00 289.75 ? 166 LEU H CD1 1 
ATOM   10138 C  CD2 . LEU D 4 166 ? 114.275 145.567 175.071 1.00 371.31 ? 166 LEU H CD2 1 
ATOM   10139 N  N   . SER D 4 167 ? 112.799 141.815 171.588 1.00 400.63 ? 167 SER H N   1 
ATOM   10140 C  CA  . SER D 4 167 ? 111.935 141.238 170.562 1.00 422.36 ? 167 SER H CA  1 
ATOM   10141 C  C   . SER D 4 167 ? 110.457 141.611 170.757 1.00 399.32 ? 167 SER H C   1 
ATOM   10142 O  O   . SER D 4 167 ? 109.648 141.276 169.889 1.00 289.93 ? 167 SER H O   1 
ATOM   10143 C  CB  . SER D 4 167 ? 112.111 139.735 170.509 1.00 466.16 ? 167 SER H CB  1 
ATOM   10144 O  OG  . SER D 4 167 ? 111.810 139.137 171.762 1.00 488.95 ? 167 SER H OG  1 
ATOM   10145 N  N   . SER D 4 168 ? 110.109 142.287 171.876 1.00 425.44 ? 168 SER H N   1 
ATOM   10146 C  CA  . SER D 4 168 ? 108.756 142.739 172.184 1.00 414.69 ? 168 SER H CA  1 
ATOM   10147 C  C   . SER D 4 168 ? 108.586 144.239 171.914 1.00 329.39 ? 168 SER H C   1 
ATOM   10148 O  O   . SER D 4 168 ? 109.372 145.054 172.400 1.00 211.32 ? 168 SER H O   1 
ATOM   10149 C  CB  . SER D 4 168 ? 108.412 142.416 173.618 1.00 446.49 ? 168 SER H CB  1 
ATOM   10150 O  OG  . SER D 4 168 ? 108.378 141.011 173.830 1.00 473.82 ? 168 SER H OG  1 
ATOM   10151 N  N   . GLY D 4 169 ? 107.546 144.587 171.139 1.00 318.75 ? 169 GLY H N   1 
ATOM   10152 C  CA  . GLY D 4 169 ? 107.204 145.967 170.829 1.00 327.28 ? 169 GLY H CA  1 
ATOM   10153 C  C   . GLY D 4 169 ? 108.120 146.613 169.787 1.00 331.40 ? 169 GLY H C   1 
ATOM   10154 O  O   . GLY D 4 169 ? 108.409 147.801 169.907 1.00 354.56 ? 169 GLY H O   1 
ATOM   10155 N  N   . VAL D 4 170 ? 108.560 145.841 168.772 1.00 280.58 ? 170 VAL H N   1 
ATOM   10156 C  CA  . VAL D 4 170 ? 109.347 146.354 167.650 1.00 233.50 ? 170 VAL H CA  1 
ATOM   10157 C  C   . VAL D 4 170 ? 108.492 146.393 166.385 1.00 241.93 ? 170 VAL H C   1 
ATOM   10158 O  O   . VAL D 4 170 ? 107.841 145.404 166.039 1.00 235.93 ? 170 VAL H O   1 
ATOM   10159 C  CB  . VAL D 4 170 ? 110.618 145.520 167.401 1.00 265.16 ? 170 VAL H CB  1 
ATOM   10160 C  CG1 . VAL D 4 170 ? 111.239 145.736 166.021 1.00 261.63 ? 170 VAL H CG1 1 
ATOM   10161 C  CG2 . VAL D 4 170 ? 111.641 145.794 168.481 1.00 287.54 ? 170 VAL H CG2 1 
ATOM   10162 N  N   . HIS D 4 171 ? 108.534 147.554 165.706 1.00 256.07 ? 171 HIS H N   1 
ATOM   10163 C  CA  . HIS D 4 171 ? 107.947 147.763 164.391 1.00 244.87 ? 171 HIS H CA  1 
ATOM   10164 C  C   . HIS D 4 171 ? 109.054 148.118 163.404 1.00 232.29 ? 171 HIS H C   1 
ATOM   10165 O  O   . HIS D 4 171 ? 109.764 149.096 163.627 1.00 258.09 ? 171 HIS H O   1 
ATOM   10166 C  CB  . HIS D 4 171 ? 106.910 148.895 164.420 1.00 192.37 ? 171 HIS H CB  1 
ATOM   10167 C  CG  . HIS D 4 171 ? 105.774 148.671 165.366 1.00 247.38 ? 171 HIS H CG  1 
ATOM   10168 N  ND1 . HIS D 4 171 ? 105.837 149.000 166.704 1.00 284.18 ? 171 HIS H ND1 1 
ATOM   10169 C  CD2 . HIS D 4 171 ? 104.543 148.151 165.168 1.00 264.90 ? 171 HIS H CD2 1 
ATOM   10170 C  CE1 . HIS D 4 171 ? 104.687 148.682 167.285 1.00 309.54 ? 171 HIS H CE1 1 
ATOM   10171 N  NE2 . HIS D 4 171 ? 103.888 148.166 166.370 1.00 277.46 ? 171 HIS H NE2 1 
ATOM   10172 N  N   . THR D 4 172 ? 109.206 147.323 162.338 1.00 192.30 ? 172 THR H N   1 
ATOM   10173 C  CA  . THR D 4 172 ? 110.145 147.630 161.275 1.00 170.75 ? 172 THR H CA  1 
ATOM   10174 C  C   . THR D 4 172 ? 109.339 147.799 159.997 1.00 180.23 ? 172 THR H C   1 
ATOM   10175 O  O   . THR D 4 172 ? 108.649 146.887 159.540 1.00 200.14 ? 172 THR H O   1 
ATOM   10176 C  CB  . THR D 4 172 ? 111.225 146.560 161.104 1.00 173.02 ? 172 THR H CB  1 
ATOM   10177 O  OG1 . THR D 4 172 ? 111.934 146.423 162.337 1.00 161.97 ? 172 THR H OG1 1 
ATOM   10178 C  CG2 . THR D 4 172 ? 112.198 146.907 159.997 1.00 170.73 ? 172 THR H CG2 1 
ATOM   10179 N  N   . PHE D 4 173 ? 109.445 148.988 159.413 1.00 179.13 ? 173 PHE H N   1 
ATOM   10180 C  CA  . PHE D 4 173 ? 108.608 149.353 158.286 1.00 164.09 ? 173 PHE H CA  1 
ATOM   10181 C  C   . PHE D 4 173 ? 109.250 148.822 157.005 1.00 156.05 ? 173 PHE H C   1 
ATOM   10182 O  O   . PHE D 4 173 ? 110.455 148.944 156.815 1.00 190.95 ? 173 PHE H O   1 
ATOM   10183 C  CB  . PHE D 4 173 ? 108.416 150.863 158.285 1.00 157.42 ? 173 PHE H CB  1 
ATOM   10184 C  CG  . PHE D 4 173 ? 107.905 151.380 159.608 1.00 182.12 ? 173 PHE H CG  1 
ATOM   10185 C  CD1 . PHE D 4 173 ? 106.563 151.262 159.941 1.00 192.52 ? 173 PHE H CD1 1 
ATOM   10186 C  CD2 . PHE D 4 173 ? 108.770 151.968 160.534 1.00 209.15 ? 173 PHE H CD2 1 
ATOM   10187 C  CE1 . PHE D 4 173 ? 106.096 151.737 161.160 1.00 221.13 ? 173 PHE H CE1 1 
ATOM   10188 C  CE2 . PHE D 4 173 ? 108.299 152.443 161.753 1.00 198.38 ? 173 PHE H CE2 1 
ATOM   10189 C  CZ  . PHE D 4 173 ? 106.959 152.328 162.060 1.00 211.43 ? 173 PHE H CZ  1 
ATOM   10190 N  N   . PRO D 4 174 ? 108.478 148.206 156.091 1.00 179.66 ? 174 PRO H N   1 
ATOM   10191 C  CA  . PRO D 4 174 ? 108.956 147.840 154.760 1.00 191.63 ? 174 PRO H CA  1 
ATOM   10192 C  C   . PRO D 4 174 ? 109.774 148.917 154.063 1.00 189.11 ? 174 PRO H C   1 
ATOM   10193 O  O   . PRO D 4 174 ? 109.530 150.109 154.244 1.00 213.42 ? 174 PRO H O   1 
ATOM   10194 C  CB  . PRO D 4 174 ? 107.654 147.641 153.963 1.00 257.01 ? 174 PRO H CB  1 
ATOM   10195 C  CG  . PRO D 4 174 ? 106.686 147.121 154.993 1.00 307.39 ? 174 PRO H CG  1 
ATOM   10196 C  CD  . PRO D 4 174 ? 107.081 147.809 156.287 1.00 272.39 ? 174 PRO H CD  1 
ATOM   10197 N  N   . ALA D 4 175 ? 110.740 148.469 153.259 1.00 206.63 ? 175 ALA H N   1 
ATOM   10198 C  CA  . ALA D 4 175 ? 111.648 149.362 152.555 1.00 208.40 ? 175 ALA H CA  1 
ATOM   10199 C  C   . ALA D 4 175 ? 110.971 150.084 151.382 1.00 210.21 ? 175 ALA H C   1 
ATOM   10200 O  O   . ALA D 4 175 ? 110.055 149.553 150.741 1.00 164.97 ? 175 ALA H O   1 
ATOM   10201 C  CB  . ALA D 4 175 ? 112.846 148.593 152.063 1.00 240.40 ? 175 ALA H CB  1 
ATOM   10202 N  N   . VAL D 4 176 ? 111.464 151.313 151.128 1.00 232.27 ? 176 VAL H N   1 
ATOM   10203 C  CA  . VAL D 4 176 ? 111.073 152.182 150.031 1.00 233.79 ? 176 VAL H CA  1 
ATOM   10204 C  C   . VAL D 4 176 ? 112.263 152.251 149.080 1.00 233.27 ? 176 VAL H C   1 
ATOM   10205 O  O   . VAL D 4 176 ? 113.376 152.501 149.543 1.00 259.20 ? 176 VAL H O   1 
ATOM   10206 C  CB  . VAL D 4 176 ? 110.714 153.595 150.542 1.00 239.75 ? 176 VAL H CB  1 
ATOM   10207 C  CG1 . VAL D 4 176 ? 110.149 154.471 149.434 1.00 235.44 ? 176 VAL H CG1 1 
ATOM   10208 C  CG2 . VAL D 4 176 ? 109.761 153.572 151.733 1.00 310.56 ? 176 VAL H CG2 1 
ATOM   10209 N  N   . LEU D 4 177 ? 112.038 152.051 147.772 1.00 200.76 ? 177 LEU H N   1 
ATOM   10210 C  CA  . LEU D 4 177 ? 113.111 152.112 146.787 1.00 213.56 ? 177 LEU H CA  1 
ATOM   10211 C  C   . LEU D 4 177 ? 113.123 153.478 146.090 1.00 278.37 ? 177 LEU H C   1 
ATOM   10212 O  O   . LEU D 4 177 ? 112.109 153.891 145.530 1.00 318.89 ? 177 LEU H O   1 
ATOM   10213 C  CB  . LEU D 4 177 ? 112.887 150.967 145.800 1.00 213.70 ? 177 LEU H CB  1 
ATOM   10214 C  CG  . LEU D 4 177 ? 113.849 150.892 144.616 1.00 255.37 ? 177 LEU H CG  1 
ATOM   10215 C  CD1 . LEU D 4 177 ? 115.273 150.742 145.092 1.00 250.96 ? 177 LEU H CD1 1 
ATOM   10216 C  CD2 . LEU D 4 177 ? 113.500 149.734 143.699 1.00 310.51 ? 177 LEU H CD2 1 
ATOM   10217 N  N   . GLN D 4 178 ? 114.284 154.158 146.126 1.00 281.62 ? 178 GLN H N   1 
ATOM   10218 C  CA  . GLN D 4 178 ? 114.468 155.497 145.584 1.00 296.58 ? 178 GLN H CA  1 
ATOM   10219 C  C   . GLN D 4 178 ? 115.791 155.586 144.828 1.00 293.11 ? 178 GLN H C   1 
ATOM   10220 O  O   . GLN D 4 178 ? 116.826 155.225 145.375 1.00 280.02 ? 178 GLN H O   1 
ATOM   10221 C  CB  . GLN D 4 178 ? 114.442 156.530 146.718 1.00 294.67 ? 178 GLN H CB  1 
ATOM   10222 C  CG  . GLN D 4 178 ? 113.044 156.828 147.230 1.00 324.79 ? 178 GLN H CG  1 
ATOM   10223 C  CD  . GLN D 4 178 ? 112.155 157.458 146.178 1.00 362.45 ? 178 GLN H CD  1 
ATOM   10224 O  OE1 . GLN D 4 178 ? 112.193 158.668 145.937 1.00 291.06 ? 178 GLN H OE1 1 
ATOM   10225 N  NE2 . GLN D 4 178 ? 111.332 156.640 145.535 1.00 399.20 ? 178 GLN H NE2 1 
ATOM   10226 N  N   . SER D 4 179 ? 115.756 156.069 143.576 1.00 316.31 ? 179 SER H N   1 
ATOM   10227 C  CA  . SER D 4 179 ? 116.940 156.222 142.735 1.00 327.48 ? 179 SER H CA  1 
ATOM   10228 C  C   . SER D 4 179 ? 117.832 154.973 142.788 1.00 304.94 ? 179 SER H C   1 
ATOM   10229 O  O   . SER D 4 179 ? 119.049 155.086 142.920 1.00 321.02 ? 179 SER H O   1 
ATOM   10230 C  CB  . SER D 4 179 ? 117.698 157.516 143.071 1.00 322.01 ? 179 SER H CB  1 
ATOM   10231 O  OG  . SER D 4 179 ? 118.201 157.548 144.401 1.00 231.68 ? 179 SER H OG  1 
ATOM   10232 N  N   . ASP D 4 180 ? 117.198 153.786 142.689 1.00 277.59 ? 180 ASP H N   1 
ATOM   10233 C  CA  . ASP D 4 180 ? 117.832 152.466 142.704 1.00 285.47 ? 180 ASP H CA  1 
ATOM   10234 C  C   . ASP D 4 180 ? 118.677 152.209 143.972 1.00 229.56 ? 180 ASP H C   1 
ATOM   10235 O  O   . ASP D 4 180 ? 119.655 151.446 143.903 1.00 213.40 ? 180 ASP H O   1 
ATOM   10236 C  CB  . ASP D 4 180 ? 118.589 152.234 141.384 1.00 371.36 ? 180 ASP H CB  1 
ATOM   10237 C  CG  . ASP D 4 180 ? 117.722 152.299 140.128 1.00 407.30 ? 180 ASP H CG  1 
ATOM   10238 O  OD1 . ASP D 4 180 ? 116.484 152.136 140.233 1.00 387.59 ? 180 ASP H OD1 1 
ATOM   10239 O  OD2 . ASP D 4 180 ? 118.293 152.519 139.041 1.00 445.68 ? 180 ASP H OD2 1 
ATOM   10240 N  N   . LEU D 4 181 ? 118.276 152.808 145.124 1.00 227.23 ? 181 LEU H N   1 
ATOM   10241 C  CA  . LEU D 4 181 ? 118.764 152.494 146.472 1.00 222.80 ? 181 LEU H CA  1 
ATOM   10242 C  C   . LEU D 4 181 ? 117.591 152.452 147.470 1.00 218.80 ? 181 LEU H C   1 
ATOM   10243 O  O   . LEU D 4 181 ? 116.657 153.243 147.377 1.00 251.69 ? 181 LEU H O   1 
ATOM   10244 C  CB  . LEU D 4 181 ? 119.777 153.556 146.902 1.00 245.75 ? 181 LEU H CB  1 
ATOM   10245 C  CG  . LEU D 4 181 ? 121.023 153.728 146.033 1.00 301.61 ? 181 LEU H CG  1 
ATOM   10246 C  CD1 . LEU D 4 181 ? 121.825 154.945 146.476 1.00 348.56 ? 181 LEU H CD1 1 
ATOM   10247 C  CD2 . LEU D 4 181 ? 121.904 152.494 146.069 1.00 258.75 ? 181 LEU H CD2 1 
ATOM   10248 N  N   . TYR D 4 182 ? 117.625 151.526 148.436 1.00 195.99 ? 182 TYR H N   1 
ATOM   10249 C  CA  . TYR D 4 182 ? 116.524 151.304 149.372 1.00 183.96 ? 182 TYR H CA  1 
ATOM   10250 C  C   . TYR D 4 182 ? 116.681 152.169 150.625 1.00 208.42 ? 182 TYR H C   1 
ATOM   10251 O  O   . TYR D 4 182 ? 117.796 152.541 150.994 1.00 230.82 ? 182 TYR H O   1 
ATOM   10252 C  CB  . TYR D 4 182 ? 116.455 149.832 149.796 1.00 161.55 ? 182 TYR H CB  1 
ATOM   10253 C  CG  . TYR D 4 182 ? 116.074 148.904 148.661 1.00 169.73 ? 182 TYR H CG  1 
ATOM   10254 C  CD1 . TYR D 4 182 ? 114.751 148.697 148.324 1.00 181.12 ? 182 TYR H CD1 1 
ATOM   10255 C  CD2 . TYR D 4 182 ? 117.037 148.248 147.909 1.00 213.28 ? 182 TYR H CD2 1 
ATOM   10256 C  CE1 . TYR D 4 182 ? 114.386 147.857 147.285 1.00 208.76 ? 182 TYR H CE1 1 
ATOM   10257 C  CE2 . TYR D 4 182 ? 116.686 147.408 146.861 1.00 246.98 ? 182 TYR H CE2 1 
ATOM   10258 C  CZ  . TYR D 4 182 ? 115.357 147.205 146.544 1.00 246.18 ? 182 TYR H CZ  1 
ATOM   10259 O  OH  . TYR D 4 182 ? 115.012 146.374 145.512 1.00 279.40 ? 182 TYR H OH  1 
ATOM   10260 N  N   . THR D 4 183 ? 115.540 152.474 151.271 1.00 227.33 ? 183 THR H N   1 
ATOM   10261 C  CA  . THR D 4 183 ? 115.469 153.146 152.564 1.00 228.51 ? 183 THR H CA  1 
ATOM   10262 C  C   . THR D 4 183 ? 114.472 152.390 153.441 1.00 212.55 ? 183 THR H C   1 
ATOM   10263 O  O   . THR D 4 183 ? 113.428 151.988 152.951 1.00 226.77 ? 183 THR H O   1 
ATOM   10264 C  CB  . THR D 4 183 ? 115.013 154.609 152.449 1.00 303.95 ? 183 THR H CB  1 
ATOM   10265 O  OG1 . THR D 4 183 ? 115.706 155.311 151.412 1.00 330.79 ? 183 THR H OG1 1 
ATOM   10266 C  CG2 . THR D 4 183 ? 115.201 155.369 153.745 1.00 309.13 ? 183 THR H CG2 1 
ATOM   10267 N  N   . LEU D 4 184 ? 114.788 152.200 154.726 1.00 185.48 ? 184 LEU H N   1 
ATOM   10268 C  CA  . LEU D 4 184 ? 113.971 151.439 155.667 1.00 158.94 ? 184 LEU H CA  1 
ATOM   10269 C  C   . LEU D 4 184 ? 114.142 152.083 157.034 1.00 151.54 ? 184 LEU H C   1 
ATOM   10270 O  O   . LEU D 4 184 ? 115.130 152.780 157.262 1.00 259.87 ? 184 LEU H O   1 
ATOM   10271 C  CB  . LEU D 4 184 ? 114.464 149.987 155.634 1.00 178.75 ? 184 LEU H CB  1 
ATOM   10272 C  CG  . LEU D 4 184 ? 114.023 149.059 156.771 1.00 189.29 ? 184 LEU H CG  1 
ATOM   10273 C  CD1 . LEU D 4 184 ? 113.794 147.645 156.248 1.00 255.41 ? 184 LEU H CD1 1 
ATOM   10274 C  CD2 . LEU D 4 184 ? 115.037 149.020 157.920 1.00 161.98 ? 184 LEU H CD2 1 
ATOM   10275 N  N   . SER D 4 185 ? 113.201 151.878 157.952 1.00 147.53 ? 185 SER H N   1 
ATOM   10276 C  CA  . SER D 4 185 ? 113.383 152.364 159.311 1.00 151.44 ? 185 SER H CA  1 
ATOM   10277 C  C   . SER D 4 185 ? 112.757 151.402 160.313 1.00 161.12 ? 185 SER H C   1 
ATOM   10278 O  O   . SER D 4 185 ? 111.801 150.691 160.008 1.00 212.91 ? 185 SER H O   1 
ATOM   10279 C  CB  . SER D 4 185 ? 112.847 153.772 159.445 1.00 185.74 ? 185 SER H CB  1 
ATOM   10280 O  OG  . SER D 4 185 ? 111.535 153.890 158.889 1.00 184.63 ? 185 SER H OG  1 
ATOM   10281 N  N   . SER D 4 186 ? 113.327 151.384 161.512 1.00 151.66 ? 186 SER H N   1 
ATOM   10282 C  CA  . SER D 4 186 ? 112.933 150.435 162.536 1.00 179.43 ? 186 SER H CA  1 
ATOM   10283 C  C   . SER D 4 186 ? 112.734 151.223 163.815 1.00 184.82 ? 186 SER H C   1 
ATOM   10284 O  O   . SER D 4 186 ? 113.405 152.232 164.030 1.00 225.99 ? 186 SER H O   1 
ATOM   10285 C  CB  . SER D 4 186 ? 113.954 149.313 162.728 1.00 219.30 ? 186 SER H CB  1 
ATOM   10286 O  OG  . SER D 4 186 ? 113.494 148.373 163.695 1.00 201.14 ? 186 SER H OG  1 
ATOM   10287 N  N   . SER D 4 187 ? 111.833 150.717 164.654 1.00 215.95 ? 187 SER H N   1 
ATOM   10288 C  CA  . SER D 4 187 ? 111.398 151.437 165.831 1.00 235.66 ? 187 SER H CA  1 
ATOM   10289 C  C   . SER D 4 187 ? 111.060 150.461 166.954 1.00 256.38 ? 187 SER H C   1 
ATOM   10290 O  O   . SER D 4 187 ? 110.634 149.333 166.714 1.00 264.03 ? 187 SER H O   1 
ATOM   10291 C  CB  . SER D 4 187 ? 110.235 152.293 165.478 1.00 237.34 ? 187 SER H CB  1 
ATOM   10292 O  OG  . SER D 4 187 ? 109.069 151.519 165.290 1.00 266.85 ? 187 SER H OG  1 
ATOM   10293 N  N   . VAL D 4 188 ? 111.258 150.945 168.179 1.00 225.82 ? 188 VAL H N   1 
ATOM   10294 C  CA  . VAL D 4 188 ? 111.061 150.177 169.390 1.00 224.57 ? 188 VAL H CA  1 
ATOM   10295 C  C   . VAL D 4 188 ? 110.566 151.143 170.470 1.00 296.03 ? 188 VAL H C   1 
ATOM   10296 O  O   . VAL D 4 188 ? 110.871 152.333 170.418 1.00 331.81 ? 188 VAL H O   1 
ATOM   10297 C  CB  . VAL D 4 188 ? 112.375 149.475 169.769 1.00 219.28 ? 188 VAL H CB  1 
ATOM   10298 C  CG1 . VAL D 4 188 ? 113.498 150.461 170.085 1.00 224.34 ? 188 VAL H CG1 1 
ATOM   10299 C  CG2 . VAL D 4 188 ? 112.179 148.503 170.921 1.00 281.87 ? 188 VAL H CG2 1 
ATOM   10300 N  N   . THR D 4 189 ? 109.796 150.638 171.444 1.00 321.99 ? 189 THR H N   1 
ATOM   10301 C  CA  . THR D 4 189 ? 109.329 151.449 172.561 1.00 322.40 ? 189 THR H CA  1 
ATOM   10302 C  C   . THR D 4 189 ? 109.696 150.753 173.874 1.00 304.73 ? 189 THR H C   1 
ATOM   10303 O  O   . THR D 4 189 ? 109.525 149.537 174.007 1.00 210.74 ? 189 THR H O   1 
ATOM   10304 C  CB  . THR D 4 189 ? 107.834 151.770 172.413 1.00 347.61 ? 189 THR H CB  1 
ATOM   10305 O  OG1 . THR D 4 189 ? 107.641 152.561 171.237 1.00 327.19 ? 189 THR H OG1 1 
ATOM   10306 C  CG2 . THR D 4 189 ? 107.271 152.531 173.594 1.00 385.20 ? 189 THR H CG2 1 
ATOM   10307 N  N   . VAL D 4 190 ? 110.195 151.556 174.832 1.00 339.51 ? 190 VAL H N   1 
ATOM   10308 C  CA  . VAL D 4 190 ? 110.724 151.066 176.099 1.00 356.05 ? 190 VAL H CA  1 
ATOM   10309 C  C   . VAL D 4 190 ? 110.226 151.951 177.247 1.00 343.98 ? 190 VAL H C   1 
ATOM   10310 O  O   . VAL D 4 190 ? 109.800 153.088 177.021 1.00 309.76 ? 190 VAL H O   1 
ATOM   10311 C  CB  . VAL D 4 190 ? 112.267 150.992 176.078 1.00 338.12 ? 190 VAL H CB  1 
ATOM   10312 C  CG1 . VAL D 4 190 ? 112.768 149.921 175.118 1.00 310.32 ? 190 VAL H CG1 1 
ATOM   10313 C  CG2 . VAL D 4 190 ? 112.910 152.344 175.775 1.00 351.92 ? 190 VAL H CG2 1 
ATOM   10314 N  N   . PRO D 4 191 ? 110.267 151.467 178.516 1.00 344.24 ? 191 PRO H N   1 
ATOM   10315 C  CA  . PRO D 4 191 ? 109.993 152.324 179.673 1.00 360.27 ? 191 PRO H CA  1 
ATOM   10316 C  C   . PRO D 4 191 ? 110.933 153.529 179.746 1.00 359.37 ? 191 PRO H C   1 
ATOM   10317 O  O   . PRO D 4 191 ? 112.118 153.414 179.427 1.00 398.53 ? 191 PRO H O   1 
ATOM   10318 C  CB  . PRO D 4 191 ? 110.204 151.391 180.879 1.00 399.04 ? 191 PRO H CB  1 
ATOM   10319 C  CG  . PRO D 4 191 ? 110.003 150.002 180.320 1.00 381.46 ? 191 PRO H CG  1 
ATOM   10320 C  CD  . PRO D 4 191 ? 110.567 150.079 178.919 1.00 345.63 ? 191 PRO H CD  1 
ATOM   10321 N  N   . SER D 4 192 ? 110.392 154.679 180.175 1.00 338.44 ? 192 SER H N   1 
ATOM   10322 C  CA  . SER D 4 192 ? 111.164 155.907 180.355 1.00 348.92 ? 192 SER H CA  1 
ATOM   10323 C  C   . SER D 4 192 ? 112.289 155.764 181.392 1.00 388.81 ? 192 SER H C   1 
ATOM   10324 O  O   . SER D 4 192 ? 113.238 156.549 181.352 1.00 380.07 ? 192 SER H O   1 
ATOM   10325 C  CB  . SER D 4 192 ? 110.249 157.066 180.703 1.00 354.36 ? 192 SER H CB  1 
ATOM   10326 O  OG  . SER D 4 192 ? 109.430 156.755 181.823 1.00 303.20 ? 192 SER H OG  1 
ATOM   10327 N  N   . SER D 4 193 ? 112.186 154.783 182.309 1.00 413.24 ? 193 SER H N   1 
ATOM   10328 C  CA  . SER D 4 193 ? 113.275 154.386 183.200 1.00 403.08 ? 193 SER H CA  1 
ATOM   10329 C  C   . SER D 4 193 ? 114.465 153.762 182.458 1.00 370.46 ? 193 SER H C   1 
ATOM   10330 O  O   . SER D 4 193 ? 115.611 153.966 182.864 1.00 330.89 ? 193 SER H O   1 
ATOM   10331 C  CB  . SER D 4 193 ? 112.765 153.441 184.269 1.00 372.51 ? 193 SER H CB  1 
ATOM   10332 O  OG  . SER D 4 193 ? 112.201 152.269 183.697 1.00 301.83 ? 193 SER H OG  1 
ATOM   10333 N  N   . THR D 4 194 ? 114.188 153.000 181.385 1.00 356.74 ? 194 THR H N   1 
ATOM   10334 C  CA  . THR D 4 194 ? 115.185 152.199 180.681 1.00 345.20 ? 194 THR H CA  1 
ATOM   10335 C  C   . THR D 4 194 ? 116.120 153.072 179.835 1.00 366.03 ? 194 THR H C   1 
ATOM   10336 O  O   . THR D 4 194 ? 117.331 152.969 180.004 1.00 411.71 ? 194 THR H O   1 
ATOM   10337 C  CB  . THR D 4 194 ? 114.508 151.078 179.867 1.00 361.39 ? 194 THR H CB  1 
ATOM   10338 O  OG1 . THR D 4 194 ? 114.240 150.009 180.775 1.00 349.53 ? 194 THR H OG1 1 
ATOM   10339 C  CG2 . THR D 4 194 ? 115.322 150.527 178.713 1.00 386.58 ? 194 THR H CG2 1 
ATOM   10340 N  N   . TRP D 4 195 ? 115.599 153.914 178.927 1.00 364.92 ? 195 TRP H N   1 
ATOM   10341 C  CA  . TRP D 4 195 ? 116.414 154.379 177.800 1.00 357.23 ? 195 TRP H CA  1 
ATOM   10342 C  C   . TRP D 4 195 ? 117.674 155.153 178.236 1.00 383.27 ? 195 TRP H C   1 
ATOM   10343 O  O   . TRP D 4 195 ? 118.763 154.750 177.832 1.00 400.56 ? 195 TRP H O   1 
ATOM   10344 C  CB  . TRP D 4 195 ? 115.595 155.174 176.769 1.00 363.86 ? 195 TRP H CB  1 
ATOM   10345 C  CG  . TRP D 4 195 ? 116.476 155.975 175.840 1.00 343.52 ? 195 TRP H CG  1 
ATOM   10346 C  CD1 . TRP D 4 195 ? 117.553 155.503 175.144 1.00 306.79 ? 195 TRP H CD1 1 
ATOM   10347 C  CD2 . TRP D 4 195 ? 116.366 157.378 175.511 1.00 367.53 ? 195 TRP H CD2 1 
ATOM   10348 N  NE1 . TRP D 4 195 ? 118.120 156.504 174.405 1.00 347.03 ? 195 TRP H NE1 1 
ATOM   10349 C  CE2 . TRP D 4 195 ? 117.416 157.665 174.606 1.00 379.65 ? 195 TRP H CE2 1 
ATOM   10350 C  CE3 . TRP D 4 195 ? 115.490 158.411 175.884 1.00 415.79 ? 195 TRP H CE3 1 
ATOM   10351 C  CZ2 . TRP D 4 195 ? 117.606 158.944 174.074 1.00 436.86 ? 195 TRP H CZ2 1 
ATOM   10352 C  CZ3 . TRP D 4 195 ? 115.682 159.673 175.357 1.00 461.74 ? 195 TRP H CZ3 1 
ATOM   10353 C  CH2 . TRP D 4 195 ? 116.726 159.934 174.464 1.00 461.08 ? 195 TRP H CH2 1 
ATOM   10354 N  N   . PRO D 4 196 ? 117.632 156.255 179.034 1.00 391.54 ? 196 PRO H N   1 
ATOM   10355 C  CA  . PRO D 4 196 ? 118.873 156.898 179.498 1.00 417.53 ? 196 PRO H CA  1 
ATOM   10356 C  C   . PRO D 4 196 ? 119.767 156.068 180.434 1.00 427.28 ? 196 PRO H C   1 
ATOM   10357 O  O   . PRO D 4 196 ? 120.934 156.420 180.607 1.00 403.23 ? 196 PRO H O   1 
ATOM   10358 C  CB  . PRO D 4 196 ? 118.375 158.158 180.239 1.00 411.90 ? 196 PRO H CB  1 
ATOM   10359 C  CG  . PRO D 4 196 ? 116.966 158.364 179.736 1.00 384.90 ? 196 PRO H CG  1 
ATOM   10360 C  CD  . PRO D 4 196 ? 116.439 156.963 179.527 1.00 358.81 ? 196 PRO H CD  1 
ATOM   10361 N  N   . SER D 4 197 ? 119.223 154.979 181.020 1.00 437.67 ? 197 SER H N   1 
ATOM   10362 C  CA  . SER D 4 197 ? 119.881 154.158 182.033 1.00 442.56 ? 197 SER H CA  1 
ATOM   10363 C  C   . SER D 4 197 ? 120.638 152.951 181.457 1.00 443.11 ? 197 SER H C   1 
ATOM   10364 O  O   . SER D 4 197 ? 121.485 152.396 182.155 1.00 453.98 ? 197 SER H O   1 
ATOM   10365 C  CB  . SER D 4 197 ? 118.858 153.681 183.047 1.00 419.17 ? 197 SER H CB  1 
ATOM   10366 O  OG  . SER D 4 197 ? 118.071 154.755 183.547 1.00 381.93 ? 197 SER H OG  1 
ATOM   10367 N  N   . GLU D 4 198 ? 120.342 152.543 180.207 1.00 441.76 ? 198 GLU H N   1 
ATOM   10368 C  CA  . GLU D 4 198 ? 120.740 151.245 179.667 1.00 446.08 ? 198 GLU H CA  1 
ATOM   10369 C  C   . GLU D 4 198 ? 121.231 151.364 178.218 1.00 451.79 ? 198 GLU H C   1 
ATOM   10370 O  O   . GLU D 4 198 ? 121.006 152.367 177.542 1.00 434.38 ? 198 GLU H O   1 
ATOM   10371 C  CB  . GLU D 4 198 ? 119.558 150.269 179.723 1.00 445.85 ? 198 GLU H CB  1 
ATOM   10372 C  CG  . GLU D 4 198 ? 118.945 150.059 181.102 1.00 426.11 ? 198 GLU H CG  1 
ATOM   10373 C  CD  . GLU D 4 198 ? 117.917 148.937 181.139 1.00 411.55 ? 198 GLU H CD  1 
ATOM   10374 O  OE1 . GLU D 4 198 ? 118.323 147.777 180.912 1.00 347.18 ? 198 GLU H OE1 1 
ATOM   10375 O  OE2 . GLU D 4 198 ? 116.719 149.218 181.388 1.00 457.58 ? 198 GLU H OE2 1 
ATOM   10376 N  N   . THR D 4 199 ? 121.912 150.309 177.739 1.00 479.32 ? 199 THR H N   1 
ATOM   10377 C  CA  . THR D 4 199 ? 122.285 150.174 176.334 1.00 504.01 ? 199 THR H CA  1 
ATOM   10378 C  C   . THR D 4 199 ? 121.032 149.973 175.478 1.00 504.94 ? 199 THR H C   1 
ATOM   10379 O  O   . THR D 4 199 ? 120.191 149.137 175.810 1.00 529.74 ? 199 THR H O   1 
ATOM   10380 C  CB  . THR D 4 199 ? 123.243 148.992 176.105 1.00 515.69 ? 199 THR H CB  1 
ATOM   10381 O  OG1 . THR D 4 199 ? 124.418 149.177 176.896 1.00 529.60 ? 199 THR H OG1 1 
ATOM   10382 C  CG2 . THR D 4 199 ? 123.662 148.816 174.659 1.00 522.67 ? 199 THR H CG2 1 
ATOM   10383 N  N   . VAL D 4 200 ? 120.916 150.737 174.375 1.00 428.97 ? 200 VAL H N   1 
ATOM   10384 C  CA  . VAL D 4 200 ? 119.978 150.421 173.298 1.00 342.12 ? 200 VAL H CA  1 
ATOM   10385 C  C   . VAL D 4 200 ? 120.695 150.527 171.950 1.00 295.16 ? 200 VAL H C   1 
ATOM   10386 O  O   . VAL D 4 200 ? 121.263 151.578 171.662 1.00 239.65 ? 200 VAL H O   1 
ATOM   10387 C  CB  . VAL D 4 200 ? 118.724 151.316 173.298 1.00 313.46 ? 200 VAL H CB  1 
ATOM   10388 C  CG1 . VAL D 4 200 ? 117.742 150.862 172.218 1.00 328.65 ? 200 VAL H CG1 1 
ATOM   10389 C  CG2 . VAL D 4 200 ? 118.039 151.367 174.658 1.00 320.55 ? 200 VAL H CG2 1 
ATOM   10390 N  N   . THR D 4 201 ? 120.644 149.448 171.136 1.00 297.35 ? 201 THR H N   1 
ATOM   10391 C  CA  . THR D 4 201 ? 121.228 149.418 169.796 1.00 302.03 ? 201 THR H CA  1 
ATOM   10392 C  C   . THR D 4 201 ? 120.285 148.795 168.770 1.00 280.94 ? 201 THR H C   1 
ATOM   10393 O  O   . THR D 4 201 ? 119.697 147.753 169.040 1.00 285.11 ? 201 THR H O   1 
ATOM   10394 C  CB  . THR D 4 201 ? 122.533 148.607 169.734 1.00 284.36 ? 201 THR H CB  1 
ATOM   10395 O  OG1 . THR D 4 201 ? 122.324 147.284 170.244 1.00 180.69 ? 201 THR H OG1 1 
ATOM   10396 C  CG2 . THR D 4 201 ? 123.662 149.266 170.495 1.00 312.79 ? 201 THR H CG2 1 
ATOM   10397 N  N   . CYS D 4 202 ? 120.161 149.419 167.586 1.00 231.25 ? 202 CYS H N   1 
ATOM   10398 C  CA  . CYS D 4 202 ? 119.700 148.694 166.409 1.00 249.82 ? 202 CYS H CA  1 
ATOM   10399 C  C   . CYS D 4 202 ? 120.878 147.891 165.843 1.00 255.38 ? 202 CYS H C   1 
ATOM   10400 O  O   . CYS D 4 202 ? 121.849 148.484 165.370 1.00 264.06 ? 202 CYS H O   1 
ATOM   10401 C  CB  . CYS D 4 202 ? 119.054 149.606 165.363 1.00 285.99 ? 202 CYS H CB  1 
ATOM   10402 S  SG  . CYS D 4 202 ? 120.044 150.986 164.726 1.00 347.89 ? 202 CYS H SG  1 
ATOM   10403 N  N   . ASN D 4 203 ? 120.780 146.547 165.907 1.00 283.35 ? 203 ASN H N   1 
ATOM   10404 C  CA  . ASN D 4 203 ? 121.773 145.625 165.367 1.00 327.86 ? 203 ASN H CA  1 
ATOM   10405 C  C   . ASN D 4 203 ? 121.477 145.337 163.887 1.00 253.16 ? 203 ASN H C   1 
ATOM   10406 O  O   . ASN D 4 203 ? 121.082 144.227 163.517 1.00 187.73 ? 203 ASN H O   1 
ATOM   10407 C  CB  . ASN D 4 203 ? 121.826 144.305 166.155 1.00 396.21 ? 203 ASN H CB  1 
ATOM   10408 C  CG  . ASN D 4 203 ? 122.187 144.404 167.627 1.00 425.97 ? 203 ASN H CG  1 
ATOM   10409 O  OD1 . ASN D 4 203 ? 121.711 145.273 168.353 1.00 382.38 ? 203 ASN H OD1 1 
ATOM   10410 N  ND2 . ASN D 4 203 ? 123.019 143.489 168.101 1.00 454.75 ? 203 ASN H ND2 1 
ATOM   10411 N  N   . VAL D 4 204 ? 121.688 146.345 163.029 1.00 210.89 ? 204 VAL H N   1 
ATOM   10412 C  CA  . VAL D 4 204 ? 121.407 146.242 161.603 1.00 220.34 ? 204 VAL H CA  1 
ATOM   10413 C  C   . VAL D 4 204 ? 122.372 145.241 160.968 1.00 242.19 ? 204 VAL H C   1 
ATOM   10414 O  O   . VAL D 4 204 ? 123.558 145.229 161.306 1.00 324.81 ? 204 VAL H O   1 
ATOM   10415 C  CB  . VAL D 4 204 ? 121.512 147.610 160.906 1.00 233.99 ? 204 VAL H CB  1 
ATOM   10416 C  CG1 . VAL D 4 204 ? 121.386 147.489 159.386 1.00 226.36 ? 204 VAL H CG1 1 
ATOM   10417 C  CG2 . VAL D 4 204 ? 120.506 148.608 161.479 1.00 253.89 ? 204 VAL H CG2 1 
ATOM   10418 N  N   . ALA D 4 205 ? 121.850 144.419 160.044 1.00 216.86 ? 205 ALA H N   1 
ATOM   10419 C  CA  . ALA D 4 205 ? 122.617 143.351 159.425 1.00 259.73 ? 205 ALA H CA  1 
ATOM   10420 C  C   . ALA D 4 205 ? 122.208 143.200 157.967 1.00 230.99 ? 205 ALA H C   1 
ATOM   10421 O  O   . ALA D 4 205 ? 121.021 143.286 157.639 1.00 322.16 ? 205 ALA H O   1 
ATOM   10422 C  CB  . ALA D 4 205 ? 122.409 142.063 160.186 1.00 301.15 ? 205 ALA H CB  1 
ATOM   10423 N  N   . HIS D 4 206 ? 123.209 142.945 157.111 1.00 220.67 ? 206 HIS H N   1 
ATOM   10424 C  CA  . HIS D 4 206 ? 123.023 142.978 155.668 1.00 245.70 ? 206 HIS H CA  1 
ATOM   10425 C  C   . HIS D 4 206 ? 123.710 141.769 155.030 1.00 210.99 ? 206 HIS H C   1 
ATOM   10426 O  O   . HIS D 4 206 ? 124.904 141.822 154.796 1.00 207.13 ? 206 HIS H O   1 
ATOM   10427 C  CB  . HIS D 4 206 ? 123.482 144.343 155.145 1.00 203.08 ? 206 HIS H CB  1 
ATOM   10428 C  CG  . HIS D 4 206 ? 123.201 144.598 153.706 1.00 204.82 ? 206 HIS H CG  1 
ATOM   10429 N  ND1 . HIS D 4 206 ? 123.581 143.794 152.657 1.00 212.20 ? 206 HIS H ND1 1 
ATOM   10430 C  CD2 . HIS D 4 206 ? 122.559 145.638 153.167 1.00 210.79 ? 206 HIS H CD2 1 
ATOM   10431 C  CE1 . HIS D 4 206 ? 123.167 144.348 151.539 1.00 213.00 ? 206 HIS H CE1 1 
ATOM   10432 N  NE2 . HIS D 4 206 ? 122.550 145.460 151.828 1.00 170.63 ? 206 HIS H NE2 1 
ATOM   10433 N  N   . PRO D 4 207 ? 122.989 140.660 154.734 1.00 256.63 ? 207 PRO H N   1 
ATOM   10434 C  CA  . PRO D 4 207 ? 123.594 139.460 154.141 1.00 292.22 ? 207 PRO H CA  1 
ATOM   10435 C  C   . PRO D 4 207 ? 124.394 139.627 152.846 1.00 285.42 ? 207 PRO H C   1 
ATOM   10436 O  O   . PRO D 4 207 ? 125.379 138.914 152.647 1.00 339.47 ? 207 PRO H O   1 
ATOM   10437 C  CB  . PRO D 4 207 ? 122.376 138.568 153.824 1.00 337.77 ? 207 PRO H CB  1 
ATOM   10438 C  CG  . PRO D 4 207 ? 121.333 138.996 154.828 1.00 365.91 ? 207 PRO H CG  1 
ATOM   10439 C  CD  . PRO D 4 207 ? 121.545 140.488 154.977 1.00 327.37 ? 207 PRO H CD  1 
ATOM   10440 N  N   . ALA D 4 208 ? 123.973 140.556 151.980 1.00 254.35 ? 208 ALA H N   1 
ATOM   10441 C  CA  . ALA D 4 208 ? 124.525 140.655 150.636 1.00 289.46 ? 208 ALA H CA  1 
ATOM   10442 C  C   . ALA D 4 208 ? 125.798 141.512 150.566 1.00 280.46 ? 208 ALA H C   1 
ATOM   10443 O  O   . ALA D 4 208 ? 126.445 141.487 149.521 1.00 296.02 ? 208 ALA H O   1 
ATOM   10444 C  CB  . ALA D 4 208 ? 123.457 141.155 149.690 1.00 304.46 ? 208 ALA H CB  1 
ATOM   10445 N  N   . SER D 4 209 ? 126.171 142.258 151.628 1.00 249.71 ? 209 SER H N   1 
ATOM   10446 C  CA  . SER D 4 209 ? 127.483 142.907 151.687 1.00 269.21 ? 209 SER H CA  1 
ATOM   10447 C  C   . SER D 4 209 ? 128.180 142.760 153.053 1.00 302.68 ? 209 SER H C   1 
ATOM   10448 O  O   . SER D 4 209 ? 129.083 143.540 153.352 1.00 309.61 ? 209 SER H O   1 
ATOM   10449 C  CB  . SER D 4 209 ? 127.383 144.365 151.241 1.00 249.66 ? 209 SER H CB  1 
ATOM   10450 O  OG  . SER D 4 209 ? 126.845 145.210 152.242 1.00 241.57 ? 209 SER H OG  1 
ATOM   10451 N  N   . SER D 4 210 ? 127.774 141.769 153.876 1.00 332.66 ? 210 SER H N   1 
ATOM   10452 C  CA  . SER D 4 210 ? 128.474 141.279 155.065 1.00 348.26 ? 210 SER H CA  1 
ATOM   10453 C  C   . SER D 4 210 ? 128.665 142.313 156.190 1.00 330.77 ? 210 SER H C   1 
ATOM   10454 O  O   . SER D 4 210 ? 129.392 142.017 157.144 1.00 320.58 ? 210 SER H O   1 
ATOM   10455 C  CB  . SER D 4 210 ? 129.784 140.624 154.660 1.00 353.25 ? 210 SER H CB  1 
ATOM   10456 O  OG  . SER D 4 210 ? 129.545 139.527 153.784 1.00 327.44 ? 210 SER H OG  1 
ATOM   10457 N  N   . THR D 4 211 ? 128.013 143.495 156.124 1.00 306.79 ? 211 THR H N   1 
ATOM   10458 C  CA  . THR D 4 211 ? 128.156 144.530 157.147 1.00 285.32 ? 211 THR H CA  1 
ATOM   10459 C  C   . THR D 4 211 ? 127.176 144.309 158.301 1.00 302.80 ? 211 THR H C   1 
ATOM   10460 O  O   . THR D 4 211 ? 125.982 144.093 158.076 1.00 367.29 ? 211 THR H O   1 
ATOM   10461 C  CB  . THR D 4 211 ? 127.949 145.945 156.593 1.00 263.32 ? 211 THR H CB  1 
ATOM   10462 O  OG1 . THR D 4 211 ? 126.694 145.982 155.922 1.00 275.23 ? 211 THR H OG1 1 
ATOM   10463 C  CG2 . THR D 4 211 ? 129.057 146.362 155.654 1.00 285.94 ? 211 THR H CG2 1 
ATOM   10464 N  N   . LYS D 4 212 ? 127.705 144.376 159.538 1.00 321.39 ? 212 LYS H N   1 
ATOM   10465 C  CA  . LYS D 4 212 ? 126.940 144.260 160.771 1.00 323.37 ? 212 LYS H CA  1 
ATOM   10466 C  C   . LYS D 4 212 ? 127.290 145.456 161.657 1.00 294.93 ? 212 LYS H C   1 
ATOM   10467 O  O   . LYS D 4 212 ? 128.470 145.701 161.918 1.00 295.76 ? 212 LYS H O   1 
ATOM   10468 C  CB  . LYS D 4 212 ? 127.244 142.920 161.452 1.00 305.18 ? 212 LYS H CB  1 
ATOM   10469 C  CG  . LYS D 4 212 ? 126.959 141.681 160.608 1.00 313.49 ? 212 LYS H CG  1 
ATOM   10470 C  CD  . LYS D 4 212 ? 127.318 140.360 161.273 1.00 390.55 ? 212 LYS H CD  1 
ATOM   10471 C  CE  . LYS D 4 212 ? 126.524 140.024 162.523 1.00 455.11 ? 212 LYS H CE  1 
ATOM   10472 N  NZ  . LYS D 4 212 ? 125.089 139.763 162.247 1.00 474.53 ? 212 LYS H NZ  1 
ATOM   10473 N  N   . VAL D 4 213 ? 126.267 146.203 162.110 1.00 291.60 ? 213 VAL H N   1 
ATOM   10474 C  CA  . VAL D 4 213 ? 126.477 147.501 162.742 1.00 311.07 ? 213 VAL H CA  1 
ATOM   10475 C  C   . VAL D 4 213 ? 125.502 147.680 163.908 1.00 290.38 ? 213 VAL H C   1 
ATOM   10476 O  O   . VAL D 4 213 ? 124.318 147.385 163.774 1.00 280.93 ? 213 VAL H O   1 
ATOM   10477 C  CB  . VAL D 4 213 ? 126.331 148.662 161.737 1.00 329.55 ? 213 VAL H CB  1 
ATOM   10478 C  CG1 . VAL D 4 213 ? 126.634 150.000 162.402 1.00 343.93 ? 213 VAL H CG1 1 
ATOM   10479 C  CG2 . VAL D 4 213 ? 127.180 148.463 160.481 1.00 293.13 ? 213 VAL H CG2 1 
ATOM   10480 N  N   . ASP D 4 214 ? 126.022 148.189 165.043 1.00 317.11 ? 214 ASP H N   1 
ATOM   10481 C  CA  . ASP D 4 214 ? 125.295 148.323 166.302 1.00 333.45 ? 214 ASP H CA  1 
ATOM   10482 C  C   . ASP D 4 214 ? 125.359 149.781 166.782 1.00 343.99 ? 214 ASP H C   1 
ATOM   10483 O  O   . ASP D 4 214 ? 126.088 150.108 167.721 1.00 353.45 ? 214 ASP H O   1 
ATOM   10484 C  CB  . ASP D 4 214 ? 125.838 147.354 167.369 1.00 377.05 ? 214 ASP H CB  1 
ATOM   10485 C  CG  . ASP D 4 214 ? 125.960 145.891 166.952 1.00 378.38 ? 214 ASP H CG  1 
ATOM   10486 O  OD1 . ASP D 4 214 ? 125.043 145.394 166.272 1.00 338.62 ? 214 ASP H OD1 1 
ATOM   10487 O  OD2 . ASP D 4 214 ? 126.973 145.251 167.317 1.00 397.54 ? 214 ASP H OD2 1 
ATOM   10488 N  N   . LYS D 4 215 ? 124.585 150.674 166.142 1.00 329.92 ? 215 LYS H N   1 
ATOM   10489 C  CA  . LYS D 4 215 ? 124.509 152.077 166.536 1.00 316.82 ? 215 LYS H CA  1 
ATOM   10490 C  C   . LYS D 4 215 ? 123.768 152.219 167.868 1.00 289.98 ? 215 LYS H C   1 
ATOM   10491 O  O   . LYS D 4 215 ? 122.653 151.722 167.996 1.00 272.86 ? 215 LYS H O   1 
ATOM   10492 C  CB  . LYS D 4 215 ? 123.792 152.895 165.456 1.00 343.59 ? 215 LYS H CB  1 
ATOM   10493 C  CG  . LYS D 4 215 ? 124.615 153.200 164.212 1.00 355.11 ? 215 LYS H CG  1 
ATOM   10494 C  CD  . LYS D 4 215 ? 125.802 154.119 164.443 1.00 377.97 ? 215 LYS H CD  1 
ATOM   10495 C  CE  . LYS D 4 215 ? 125.431 155.496 164.960 1.00 421.39 ? 215 LYS H CE  1 
ATOM   10496 N  NZ  . LYS D 4 215 ? 126.630 156.354 165.112 1.00 456.43 ? 215 LYS H NZ  1 
ATOM   10497 N  N   . LYS D 4 216 ? 124.387 152.899 168.848 1.00 297.32 ? 216 LYS H N   1 
ATOM   10498 C  CA  . LYS D 4 216 ? 123.760 153.175 170.135 1.00 339.45 ? 216 LYS H CA  1 
ATOM   10499 C  C   . LYS D 4 216 ? 122.891 154.431 170.048 1.00 338.13 ? 216 LYS H C   1 
ATOM   10500 O  O   . LYS D 4 216 ? 123.294 155.418 169.434 1.00 279.10 ? 216 LYS H O   1 
ATOM   10501 C  CB  . LYS D 4 216 ? 124.815 153.350 171.231 1.00 411.83 ? 216 LYS H CB  1 
ATOM   10502 C  CG  . LYS D 4 216 ? 125.497 152.060 171.657 1.00 451.39 ? 216 LYS H CG  1 
ATOM   10503 C  CD  . LYS D 4 216 ? 126.469 152.234 172.806 1.00 485.20 ? 216 LYS H CD  1 
ATOM   10504 C  CE  . LYS D 4 216 ? 127.032 150.926 173.324 1.00 505.51 ? 216 LYS H CE  1 
ATOM   10505 N  NZ  . LYS D 4 216 ? 127.926 150.265 172.343 1.00 523.17 ? 216 LYS H NZ  1 
ATOM   10506 N  N   . ILE D 4 217 ? 121.709 154.390 170.688 1.00 363.24 ? 217 ILE H N   1 
ATOM   10507 C  CA  . ILE D 4 217 ? 120.755 155.494 170.656 1.00 386.51 ? 217 ILE H CA  1 
ATOM   10508 C  C   . ILE D 4 217 ? 121.061 156.443 171.821 1.00 394.69 ? 217 ILE H C   1 
ATOM   10509 O  O   . ILE D 4 217 ? 120.563 156.249 172.935 1.00 375.20 ? 217 ILE H O   1 
ATOM   10510 C  CB  . ILE D 4 217 ? 119.288 155.000 170.690 1.00 397.29 ? 217 ILE H CB  1 
ATOM   10511 C  CG1 . ILE D 4 217 ? 119.018 153.791 169.783 1.00 382.12 ? 217 ILE H CG1 1 
ATOM   10512 C  CG2 . ILE D 4 217 ? 118.337 156.154 170.381 1.00 418.98 ? 217 ILE H CG2 1 
ATOM   10513 C  CD1 . ILE D 4 217 ? 119.394 153.966 168.334 1.00 361.12 ? 217 ILE H CD1 1 
ATOM   10514 N  N   . VAL D 4 218 ? 121.873 157.481 171.546 1.00 396.06 ? 218 VAL H N   1 
ATOM   10515 C  CA  . VAL D 4 218 ? 122.378 158.398 172.564 1.00 432.76 ? 218 VAL H CA  1 
ATOM   10516 C  C   . VAL D 4 218 ? 121.547 159.688 172.546 1.00 401.85 ? 218 VAL H C   1 
ATOM   10517 O  O   . VAL D 4 218 ? 121.273 160.212 171.465 1.00 374.41 ? 218 VAL H O   1 
ATOM   10518 C  CB  . VAL D 4 218 ? 123.880 158.687 172.353 1.00 500.22 ? 218 VAL H CB  1 
ATOM   10519 C  CG1 . VAL D 4 218 ? 124.444 159.661 173.383 1.00 520.45 ? 218 VAL H CG1 1 
ATOM   10520 C  CG2 . VAL D 4 218 ? 124.706 157.408 172.349 1.00 527.88 ? 218 VAL H CG2 1 
ATOM   10521 N  N   . PRO D 4 219 ? 121.125 160.248 173.717 1.00 394.89 ? 219 PRO H N   1 
ATOM   10522 C  CA  . PRO D 4 219 ? 120.389 161.523 173.759 1.00 406.22 ? 219 PRO H CA  1 
ATOM   10523 C  C   . PRO D 4 219 ? 121.110 162.733 173.150 1.00 442.46 ? 219 PRO H C   1 
ATOM   10524 O  O   . PRO D 4 219 ? 122.335 162.749 173.044 1.00 457.30 ? 219 PRO H O   1 
ATOM   10525 C  CB  . PRO D 4 219 ? 120.169 161.788 175.266 1.00 387.80 ? 219 PRO H CB  1 
ATOM   10526 C  CG  . PRO D 4 219 ? 120.329 160.443 175.936 1.00 354.66 ? 219 PRO H CG  1 
ATOM   10527 C  CD  . PRO D 4 219 ? 121.311 159.686 175.069 1.00 368.37 ? 219 PRO H CD  1 
ATOM   10528 N  N   . ARG D 4 220 ? 120.328 163.750 172.756 1.00 449.93 ? 220 ARG H N   1 
ATOM   10529 C  CA  . ARG D 4 220 ? 120.846 164.924 172.067 1.00 446.00 ? 220 ARG H CA  1 
ATOM   10530 C  C   . ARG D 4 220 ? 121.572 165.842 173.064 1.00 436.25 ? 220 ARG H C   1 
ATOM   10531 O  O   . ARG D 4 220 ? 120.884 166.493 173.879 1.00 365.20 ? 220 ARG H O   1 
ATOM   10532 C  CB  . ARG D 4 220 ? 119.705 165.645 171.342 1.00 424.00 ? 220 ARG H CB  1 
ATOM   10533 C  CG  . ARG D 4 220 ? 119.056 164.808 170.248 1.00 402.05 ? 220 ARG H CG  1 
ATOM   10534 C  CD  . ARG D 4 220 ? 117.980 165.562 169.488 1.00 411.42 ? 220 ARG H CD  1 
ATOM   10535 N  NE  . ARG D 4 220 ? 118.489 166.626 168.623 1.00 398.93 ? 220 ARG H NE  1 
ATOM   10536 C  CZ  . ARG D 4 220 ? 118.982 166.465 167.392 1.00 424.71 ? 220 ARG H CZ  1 
ATOM   10537 N  NH1 . ARG D 4 220 ? 119.049 165.263 166.841 1.00 436.62 ? 220 ARG H NH1 1 
ATOM   10538 N  NH2 . ARG D 4 220 ? 119.408 167.516 166.705 1.00 418.29 ? 220 ARG H NH2 1 
HETATM 10539 C  C1  . NAG E 5 .   ? 107.918 78.921  150.451 1.00 271.85 ? 701 NAG A C1  1 
HETATM 10540 C  C2  . NAG E 5 .   ? 107.109 79.633  151.544 1.00 258.58 ? 701 NAG A C2  1 
HETATM 10541 C  C3  . NAG E 5 .   ? 107.946 79.706  152.820 1.00 325.67 ? 701 NAG A C3  1 
HETATM 10542 C  C4  . NAG E 5 .   ? 108.408 78.307  153.219 1.00 333.77 ? 701 NAG A C4  1 
HETATM 10543 C  C5  . NAG E 5 .   ? 109.152 77.651  152.051 1.00 293.13 ? 701 NAG A C5  1 
HETATM 10544 C  C6  . NAG E 5 .   ? 109.600 76.241  152.391 1.00 307.29 ? 701 NAG A C6  1 
HETATM 10545 C  C7  . NAG E 5 .   ? 105.490 81.175  150.483 1.00 329.89 ? 701 NAG A C7  1 
HETATM 10546 C  C8  . NAG E 5 .   ? 105.174 82.598  150.130 1.00 365.11 ? 701 NAG A C8  1 
HETATM 10547 N  N2  . NAG E 5 .   ? 106.628 80.956  151.168 1.00 286.89 ? 701 NAG A N2  1 
HETATM 10548 O  O3  . NAG E 5 .   ? 107.231 80.324  153.888 1.00 407.56 ? 701 NAG A O3  1 
HETATM 10549 O  O4  . NAG E 5 .   ? 109.268 78.405  154.357 1.00 355.86 ? 701 NAG A O4  1 
HETATM 10550 O  O5  . NAG E 5 .   ? 108.327 77.611  150.853 1.00 262.53 ? 701 NAG A O5  1 
HETATM 10551 O  O6  . NAG E 5 .   ? 108.504 75.369  152.703 1.00 345.70 ? 701 NAG A O6  1 
HETATM 10552 O  O7  . NAG E 5 .   ? 104.751 80.252  150.145 1.00 293.86 ? 701 NAG A O7  1 
HETATM 10553 C  C1  . NAG F 5 .   ? 80.993  96.386  136.852 1.00 309.47 ? 702 NAG A C1  1 
HETATM 10554 C  C2  . NAG F 5 .   ? 82.009  97.295  137.556 1.00 316.07 ? 702 NAG A C2  1 
HETATM 10555 C  C3  . NAG F 5 .   ? 81.568  97.667  138.984 1.00 369.58 ? 702 NAG A C3  1 
HETATM 10556 C  C4  . NAG F 5 .   ? 80.087  98.041  139.072 1.00 355.96 ? 702 NAG A C4  1 
HETATM 10557 C  C5  . NAG F 5 .   ? 79.235  96.963  138.395 1.00 329.21 ? 702 NAG A C5  1 
HETATM 10558 C  C6  . NAG F 5 .   ? 77.739  97.251  138.431 1.00 301.91 ? 702 NAG A C6  1 
HETATM 10559 C  C7  . NAG F 5 .   ? 83.669  95.492  138.080 1.00 312.43 ? 702 NAG A C7  1 
HETATM 10560 C  C8  . NAG F 5 .   ? 84.983  94.892  137.674 1.00 283.70 ? 702 NAG A C8  1 
HETATM 10561 N  N2  . NAG F 5 .   ? 83.344  96.702  137.570 1.00 341.83 ? 702 NAG A N2  1 
HETATM 10562 O  O3  . NAG F 5 .   ? 82.379  98.725  139.495 1.00 393.66 ? 702 NAG A O3  1 
HETATM 10563 O  O4  . NAG F 5 .   ? 79.730  98.157  140.452 1.00 289.66 ? 702 NAG A O4  1 
HETATM 10564 O  O5  . NAG F 5 .   ? 79.649  96.848  137.011 1.00 320.24 ? 702 NAG A O5  1 
HETATM 10565 O  O6  . NAG F 5 .   ? 77.399  98.475  137.780 1.00 360.35 ? 702 NAG A O6  1 
HETATM 10566 O  O7  . NAG F 5 .   ? 82.912  94.882  138.826 1.00 296.51 ? 702 NAG A O7  1 
HETATM 10567 C  C1  . NAG G 5 .   ? 123.458 66.682  128.744 1.00 395.80 ? 703 NAG A C1  1 
HETATM 10568 C  C2  . NAG G 5 .   ? 124.549 65.618  128.749 1.00 410.29 ? 703 NAG A C2  1 
HETATM 10569 C  C3  . NAG G 5 .   ? 125.880 66.280  128.386 1.00 444.74 ? 703 NAG A C3  1 
HETATM 10570 C  C4  . NAG G 5 .   ? 125.773 66.974  127.027 1.00 504.22 ? 703 NAG A C4  1 
HETATM 10571 C  C5  . NAG G 5 .   ? 124.559 67.915  126.966 1.00 491.12 ? 703 NAG A C5  1 
HETATM 10572 C  C6  . NAG G 5 .   ? 124.259 68.402  125.553 1.00 480.22 ? 703 NAG A C6  1 
HETATM 10573 C  C7  . NAG G 5 .   ? 123.880 63.820  130.301 1.00 430.58 ? 703 NAG A C7  1 
HETATM 10574 C  C8  . NAG G 5 .   ? 124.203 63.098  131.577 1.00 465.08 ? 703 NAG A C8  1 
HETATM 10575 N  N2  . NAG G 5 .   ? 124.629 64.894  130.007 1.00 424.62 ? 703 NAG A N2  1 
HETATM 10576 O  O3  . NAG G 5 .   ? 126.951 65.339  128.383 1.00 408.51 ? 703 NAG A O3  1 
HETATM 10577 O  O4  . NAG G 5 .   ? 126.984 67.704  126.818 1.00 525.74 ? 703 NAG A O4  1 
HETATM 10578 O  O5  . NAG G 5 .   ? 123.358 67.254  127.438 1.00 417.20 ? 703 NAG A O5  1 
HETATM 10579 O  O6  . NAG G 5 .   ? 123.166 69.330  125.497 1.00 400.50 ? 703 NAG A O6  1 
HETATM 10580 O  O7  . NAG G 5 .   ? 122.971 63.441  129.566 1.00 401.49 ? 703 NAG A O7  1 
HETATM 10581 C  C1  . NAG H 5 .   ? 124.361 95.926  136.752 1.00 294.54 ? 704 NAG A C1  1 
HETATM 10582 C  C2  . NAG H 5 .   ? 125.636 95.250  136.243 1.00 343.94 ? 704 NAG A C2  1 
HETATM 10583 C  C3  . NAG H 5 .   ? 126.846 96.156  136.499 1.00 399.32 ? 704 NAG A C3  1 
HETATM 10584 C  C4  . NAG H 5 .   ? 126.615 97.547  135.908 1.00 401.51 ? 704 NAG A C4  1 
HETATM 10585 C  C5  . NAG H 5 .   ? 125.316 98.151  136.448 1.00 404.50 ? 704 NAG A C5  1 
HETATM 10586 C  C6  . NAG H 5 .   ? 124.951 99.483  135.803 1.00 457.41 ? 704 NAG A C6  1 
HETATM 10587 C  C7  . NAG H 5 .   ? 125.911 93.566  138.076 1.00 346.85 ? 704 NAG A C7  1 
HETATM 10588 C  C8  . NAG H 5 .   ? 126.101 92.109  138.387 1.00 309.27 ? 704 NAG A C8  1 
HETATM 10589 N  N2  . NAG H 5 .   ? 125.796 93.904  136.774 1.00 377.31 ? 704 NAG A N2  1 
HETATM 10590 O  O3  . NAG H 5 .   ? 128.040 95.585  135.971 1.00 440.32 ? 704 NAG A O3  1 
HETATM 10591 O  O4  . NAG H 5 .   ? 127.720 98.379  136.258 1.00 405.15 ? 704 NAG A O4  1 
HETATM 10592 O  O5  . NAG H 5 .   ? 124.220 97.242  136.196 1.00 317.43 ? 704 NAG A O5  1 
HETATM 10593 O  O6  . NAG H 5 .   ? 125.953 100.486 136.016 1.00 499.51 ? 704 NAG A O6  1 
HETATM 10594 O  O7  . NAG H 5 .   ? 125.867 94.398  138.977 1.00 282.85 ? 704 NAG A O7  1 
HETATM 10595 N  N1  . VRW I 6 .   ? 97.682  100.873 87.881  1.00 189.97 ? 601 VRW B N1  1 
HETATM 10596 N  N3  . VRW I 6 .   ? 94.246  102.812 84.936  1.00 265.38 ? 601 VRW B N3  1 
HETATM 10597 C  C4  . VRW I 6 .   ? 99.569  99.361  88.357  1.00 174.93 ? 601 VRW B C4  1 
HETATM 10598 C  C5  . VRW I 6 .   ? 100.538 98.531  87.762  1.00 199.28 ? 601 VRW B C5  1 
HETATM 10599 C  C6  . VRW I 6 .   ? 101.563 97.991  88.535  1.00 238.76 ? 601 VRW B C6  1 
HETATM 10600 C  C2  . VRW I 6 .   ? 100.681 99.119  90.476  1.00 214.41 ? 601 VRW B C2  1 
HETATM 10601 C  C1  . VRW I 6 .   ? 101.636 98.285  89.889  1.00 239.58 ? 601 VRW B C1  1 
HETATM 10602 C  C3  . VRW I 6 .   ? 99.650  99.670  89.721  1.00 138.84 ? 601 VRW B C3  1 
HETATM 10603 C  C7  . VRW I 6 .   ? 98.520  99.941  87.544  1.00 168.73 ? 601 VRW B C7  1 
HETATM 10604 C  C8  . VRW I 6 .   ? 96.918  101.092 86.732  1.00 210.72 ? 601 VRW B C8  1 
HETATM 10605 C  C9  . VRW I 6 .   ? 95.870  101.973 86.491  1.00 217.18 ? 601 VRW B C9  1 
HETATM 10606 C  C10 . VRW I 6 .   ? 95.295  101.957 85.226  1.00 260.66 ? 601 VRW B C10 1 
HETATM 10607 C  C11 . VRW I 6 .   ? 95.757  101.081 84.215  1.00 291.39 ? 601 VRW B C11 1 
HETATM 10608 C  C12 . VRW I 6 .   ? 96.808  100.199 84.455  1.00 284.66 ? 601 VRW B C12 1 
HETATM 10609 C  C13 . VRW I 6 .   ? 97.371  100.236 85.730  1.00 212.62 ? 601 VRW B C13 1 
HETATM 10610 O  O1  . VRW I 6 .   ? 98.408  99.497  86.257  1.00 172.95 ? 601 VRW B O1  1 
HETATM 10611 C  C14 . VRW I 6 .   ? 97.290  99.270  83.368  1.00 313.76 ? 601 VRW B C14 1 
HETATM 10612 O  O2  . VRW I 6 .   ? 96.679  97.964  83.515  1.00 228.88 ? 601 VRW B O2  1 
HETATM 10613 C  C15 . VRW I 6 .   ? 97.200  97.127  84.472  1.00 138.02 ? 601 VRW B C15 1 
HETATM 10614 C  C16 . VRW I 6 .   ? 98.436  96.489  84.323  1.00 143.06 ? 601 VRW B C16 1 
HETATM 10615 C  C17 . VRW I 6 .   ? 98.960  95.681  85.288  1.00 157.87 ? 601 VRW B C17 1 
HETATM 10616 C  C18 . VRW I 6 .   ? 98.282  95.460  86.469  1.00 179.65 ? 601 VRW B C18 1 
HETATM 10617 C  C19 . VRW I 6 .   ? 97.054  96.089  86.669  1.00 215.61 ? 601 VRW B C19 1 
HETATM 10618 C  C20 . VRW I 6 .   ? 96.519  96.913  85.700  1.00 215.30 ? 601 VRW B C20 1 
HETATM 10619 CL CL1 . VRW I 6 .   ? 94.979  97.667  86.004  1.00 329.86 ? 601 VRW B CL1 1 
HETATM 10620 C  C21 . VRW I 6 .   ? 98.892  94.546  87.507  1.00 215.49 ? 601 VRW B C21 1 
HETATM 10621 C  C22 . VRW I 6 .   ? 99.450  93.209  86.983  1.00 195.05 ? 601 VRW B C22 1 
HETATM 10622 C  C23 . VRW I 6 .   ? 100.317 92.510  88.037  1.00 216.21 ? 601 VRW B C23 1 
HETATM 10623 O  O3  . VRW I 6 .   ? 100.139 91.286  88.178  1.00 207.71 ? 601 VRW B O3  1 
HETATM 10624 O  O4  . VRW I 6 .   ? 101.162 93.197  88.676  1.00 258.62 ? 601 VRW B O4  1 
HETATM 10625 N  N2  . VRW I 6 .   ? 98.342  92.315  86.535  1.00 167.40 ? 601 VRW B N2  1 
HETATM 10626 CL CL2 . VRW I 6 .   ? 99.408  96.659  82.904  1.00 362.72 ? 601 VRW B CL2 1 
# 
