data_9K7N
# 
_entry.id   9K7N 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9K7N         pdb_00009k7n 10.2210/pdb9k7n/pdb 
WWPDB D_1300052919 ?            ?                   
EMDB  EMD-62150    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-26 ? 
2 'EM metadata'     1 0 2025-02-26 ? 
3 FSC               1 0 2025-02-26 ? 
4 'Half map'        1 0 2025-02-26 1 
5 'Half map'        1 0 2025-02-26 2 
6 Image             1 0 2025-02-26 ? 
7 'Primary map'     1 0 2025-02-26 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9K7N 
_pdbx_database_status.recvd_initial_deposition_date   2024-10-24 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Cryo-EM structure of human taurine transporter TAUT bound taurine in an occluded state in the saposin-disc' 
_pdbx_database_related.db_id          EMD-62150 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              zhangheng@simm.ac.cn 
_pdbx_contact_author.name_first         Zhang 
_pdbx_contact_author.name_last          Heng 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-9441-8277 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zhang, H.' 1 ? 
'Xu, E.H.'  2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   CN 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Res.' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1001-0602 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Cryo-EM structure of human taurine transporter TAUT bound taurine in an occluded state in the saposin-disc' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zhang, H.' 1 ? 
primary 'Xu, E.H.'  2 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Sodium- and chloride-dependent taurine transporter' 71211.000 1 ? ? ? ? 
2 non-polymer syn '2-AMINOETHANESULFONIC ACID'                         125.147   1 ? ? ? ? 
3 non-polymer syn 'CHLORIDE ION'                                       35.453    1 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Solute carrier family 6 member 6' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MDYKDDDDKGSGMATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFP
YLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYY
LFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVW
LVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGA
MTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWS
ILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCL
LWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWS
LALSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTPREPNRWAVEREGATPYNSRTVMNGALVKPTHIIVETMM
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MDYKDDDDKGSGMATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFP
YLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYY
LFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVW
LVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGA
MTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWS
ILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCL
LWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWS
LALSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTPREPNRWAVEREGATPYNSRTVMNGALVKPTHIIVETMM
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '2-AMINOETHANESULFONIC ACID' TAU 
3 'CHLORIDE ION'               CL  
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ASP n 
1 3   TYR n 
1 4   LYS n 
1 5   ASP n 
1 6   ASP n 
1 7   ASP n 
1 8   ASP n 
1 9   LYS n 
1 10  GLY n 
1 11  SER n 
1 12  GLY n 
1 13  MET n 
1 14  ALA n 
1 15  THR n 
1 16  LYS n 
1 17  GLU n 
1 18  LYS n 
1 19  LEU n 
1 20  GLN n 
1 21  CYS n 
1 22  LEU n 
1 23  LYS n 
1 24  ASP n 
1 25  PHE n 
1 26  HIS n 
1 27  LYS n 
1 28  ASP n 
1 29  ILE n 
1 30  LEU n 
1 31  LYS n 
1 32  PRO n 
1 33  SER n 
1 34  PRO n 
1 35  GLY n 
1 36  LYS n 
1 37  SER n 
1 38  PRO n 
1 39  GLY n 
1 40  THR n 
1 41  ARG n 
1 42  PRO n 
1 43  GLU n 
1 44  ASP n 
1 45  GLU n 
1 46  ALA n 
1 47  GLU n 
1 48  GLY n 
1 49  LYS n 
1 50  PRO n 
1 51  PRO n 
1 52  GLN n 
1 53  ARG n 
1 54  GLU n 
1 55  LYS n 
1 56  TRP n 
1 57  SER n 
1 58  SER n 
1 59  LYS n 
1 60  ILE n 
1 61  ASP n 
1 62  PHE n 
1 63  VAL n 
1 64  LEU n 
1 65  SER n 
1 66  VAL n 
1 67  ALA n 
1 68  GLY n 
1 69  GLY n 
1 70  PHE n 
1 71  VAL n 
1 72  GLY n 
1 73  LEU n 
1 74  GLY n 
1 75  ASN n 
1 76  VAL n 
1 77  TRP n 
1 78  ARG n 
1 79  PHE n 
1 80  PRO n 
1 81  TYR n 
1 82  LEU n 
1 83  CYS n 
1 84  TYR n 
1 85  LYS n 
1 86  ASN n 
1 87  GLY n 
1 88  GLY n 
1 89  GLY n 
1 90  ALA n 
1 91  PHE n 
1 92  LEU n 
1 93  ILE n 
1 94  PRO n 
1 95  TYR n 
1 96  PHE n 
1 97  ILE n 
1 98  PHE n 
1 99  LEU n 
1 100 PHE n 
1 101 GLY n 
1 102 SER n 
1 103 GLY n 
1 104 LEU n 
1 105 PRO n 
1 106 VAL n 
1 107 PHE n 
1 108 PHE n 
1 109 LEU n 
1 110 GLU n 
1 111 ILE n 
1 112 ILE n 
1 113 ILE n 
1 114 GLY n 
1 115 GLN n 
1 116 TYR n 
1 117 THR n 
1 118 SER n 
1 119 GLU n 
1 120 GLY n 
1 121 GLY n 
1 122 ILE n 
1 123 THR n 
1 124 CYS n 
1 125 TRP n 
1 126 GLU n 
1 127 LYS n 
1 128 ILE n 
1 129 CYS n 
1 130 PRO n 
1 131 LEU n 
1 132 PHE n 
1 133 SER n 
1 134 GLY n 
1 135 ILE n 
1 136 GLY n 
1 137 TYR n 
1 138 ALA n 
1 139 SER n 
1 140 VAL n 
1 141 VAL n 
1 142 ILE n 
1 143 VAL n 
1 144 SER n 
1 145 LEU n 
1 146 LEU n 
1 147 ASN n 
1 148 VAL n 
1 149 TYR n 
1 150 TYR n 
1 151 ILE n 
1 152 VAL n 
1 153 ILE n 
1 154 LEU n 
1 155 ALA n 
1 156 TRP n 
1 157 ALA n 
1 158 THR n 
1 159 TYR n 
1 160 TYR n 
1 161 LEU n 
1 162 PHE n 
1 163 GLN n 
1 164 SER n 
1 165 PHE n 
1 166 GLN n 
1 167 LYS n 
1 168 GLU n 
1 169 LEU n 
1 170 PRO n 
1 171 TRP n 
1 172 ALA n 
1 173 HIS n 
1 174 CYS n 
1 175 ASN n 
1 176 HIS n 
1 177 SER n 
1 178 TRP n 
1 179 ASN n 
1 180 THR n 
1 181 PRO n 
1 182 HIS n 
1 183 CYS n 
1 184 MET n 
1 185 GLU n 
1 186 ASP n 
1 187 THR n 
1 188 MET n 
1 189 ARG n 
1 190 LYS n 
1 191 ASN n 
1 192 LYS n 
1 193 SER n 
1 194 VAL n 
1 195 TRP n 
1 196 ILE n 
1 197 THR n 
1 198 ILE n 
1 199 SER n 
1 200 SER n 
1 201 THR n 
1 202 ASN n 
1 203 PHE n 
1 204 THR n 
1 205 SER n 
1 206 PRO n 
1 207 VAL n 
1 208 ILE n 
1 209 GLU n 
1 210 PHE n 
1 211 TRP n 
1 212 GLU n 
1 213 ARG n 
1 214 ASN n 
1 215 VAL n 
1 216 LEU n 
1 217 SER n 
1 218 LEU n 
1 219 SER n 
1 220 PRO n 
1 221 GLY n 
1 222 ILE n 
1 223 ASP n 
1 224 HIS n 
1 225 PRO n 
1 226 GLY n 
1 227 SER n 
1 228 LEU n 
1 229 LYS n 
1 230 TRP n 
1 231 ASP n 
1 232 LEU n 
1 233 ALA n 
1 234 LEU n 
1 235 CYS n 
1 236 LEU n 
1 237 LEU n 
1 238 LEU n 
1 239 VAL n 
1 240 TRP n 
1 241 LEU n 
1 242 VAL n 
1 243 CYS n 
1 244 PHE n 
1 245 PHE n 
1 246 CYS n 
1 247 ILE n 
1 248 TRP n 
1 249 LYS n 
1 250 GLY n 
1 251 VAL n 
1 252 ARG n 
1 253 SER n 
1 254 THR n 
1 255 GLY n 
1 256 LYS n 
1 257 VAL n 
1 258 VAL n 
1 259 TYR n 
1 260 PHE n 
1 261 THR n 
1 262 ALA n 
1 263 THR n 
1 264 PHE n 
1 265 PRO n 
1 266 PHE n 
1 267 ALA n 
1 268 MET n 
1 269 LEU n 
1 270 LEU n 
1 271 VAL n 
1 272 LEU n 
1 273 LEU n 
1 274 VAL n 
1 275 ARG n 
1 276 GLY n 
1 277 LEU n 
1 278 THR n 
1 279 LEU n 
1 280 PRO n 
1 281 GLY n 
1 282 ALA n 
1 283 GLY n 
1 284 ALA n 
1 285 GLY n 
1 286 ILE n 
1 287 LYS n 
1 288 PHE n 
1 289 TYR n 
1 290 LEU n 
1 291 TYR n 
1 292 PRO n 
1 293 ASP n 
1 294 ILE n 
1 295 THR n 
1 296 ARG n 
1 297 LEU n 
1 298 GLU n 
1 299 ASP n 
1 300 PRO n 
1 301 GLN n 
1 302 VAL n 
1 303 TRP n 
1 304 ILE n 
1 305 ASP n 
1 306 ALA n 
1 307 GLY n 
1 308 THR n 
1 309 GLN n 
1 310 ILE n 
1 311 PHE n 
1 312 PHE n 
1 313 SER n 
1 314 TYR n 
1 315 ALA n 
1 316 ILE n 
1 317 CYS n 
1 318 LEU n 
1 319 GLY n 
1 320 ALA n 
1 321 MET n 
1 322 THR n 
1 323 SER n 
1 324 LEU n 
1 325 GLY n 
1 326 SER n 
1 327 TYR n 
1 328 ASN n 
1 329 LYS n 
1 330 TYR n 
1 331 LYS n 
1 332 TYR n 
1 333 ASN n 
1 334 SER n 
1 335 TYR n 
1 336 ARG n 
1 337 ASP n 
1 338 CYS n 
1 339 MET n 
1 340 LEU n 
1 341 LEU n 
1 342 GLY n 
1 343 CYS n 
1 344 LEU n 
1 345 ASN n 
1 346 SER n 
1 347 GLY n 
1 348 THR n 
1 349 SER n 
1 350 PHE n 
1 351 VAL n 
1 352 SER n 
1 353 GLY n 
1 354 PHE n 
1 355 ALA n 
1 356 ILE n 
1 357 PHE n 
1 358 SER n 
1 359 ILE n 
1 360 LEU n 
1 361 GLY n 
1 362 PHE n 
1 363 MET n 
1 364 ALA n 
1 365 GLN n 
1 366 GLU n 
1 367 GLN n 
1 368 GLY n 
1 369 VAL n 
1 370 ASP n 
1 371 ILE n 
1 372 ALA n 
1 373 ASP n 
1 374 VAL n 
1 375 ALA n 
1 376 GLU n 
1 377 SER n 
1 378 GLY n 
1 379 PRO n 
1 380 GLY n 
1 381 LEU n 
1 382 ALA n 
1 383 PHE n 
1 384 ILE n 
1 385 ALA n 
1 386 TYR n 
1 387 PRO n 
1 388 LYS n 
1 389 ALA n 
1 390 VAL n 
1 391 THR n 
1 392 MET n 
1 393 MET n 
1 394 PRO n 
1 395 LEU n 
1 396 PRO n 
1 397 THR n 
1 398 PHE n 
1 399 TRP n 
1 400 SER n 
1 401 ILE n 
1 402 LEU n 
1 403 PHE n 
1 404 PHE n 
1 405 ILE n 
1 406 MET n 
1 407 LEU n 
1 408 LEU n 
1 409 LEU n 
1 410 LEU n 
1 411 GLY n 
1 412 LEU n 
1 413 ASP n 
1 414 SER n 
1 415 GLN n 
1 416 PHE n 
1 417 VAL n 
1 418 GLU n 
1 419 VAL n 
1 420 GLU n 
1 421 GLY n 
1 422 GLN n 
1 423 ILE n 
1 424 THR n 
1 425 SER n 
1 426 LEU n 
1 427 VAL n 
1 428 ASP n 
1 429 LEU n 
1 430 TYR n 
1 431 PRO n 
1 432 SER n 
1 433 PHE n 
1 434 LEU n 
1 435 ARG n 
1 436 LYS n 
1 437 GLY n 
1 438 TYR n 
1 439 ARG n 
1 440 ARG n 
1 441 GLU n 
1 442 ILE n 
1 443 PHE n 
1 444 ILE n 
1 445 ALA n 
1 446 PHE n 
1 447 VAL n 
1 448 CYS n 
1 449 SER n 
1 450 ILE n 
1 451 SER n 
1 452 TYR n 
1 453 LEU n 
1 454 LEU n 
1 455 GLY n 
1 456 LEU n 
1 457 THR n 
1 458 MET n 
1 459 VAL n 
1 460 THR n 
1 461 GLU n 
1 462 GLY n 
1 463 GLY n 
1 464 MET n 
1 465 TYR n 
1 466 VAL n 
1 467 PHE n 
1 468 GLN n 
1 469 LEU n 
1 470 PHE n 
1 471 ASP n 
1 472 TYR n 
1 473 TYR n 
1 474 ALA n 
1 475 ALA n 
1 476 SER n 
1 477 GLY n 
1 478 VAL n 
1 479 CYS n 
1 480 LEU n 
1 481 LEU n 
1 482 TRP n 
1 483 VAL n 
1 484 ALA n 
1 485 PHE n 
1 486 PHE n 
1 487 GLU n 
1 488 CYS n 
1 489 PHE n 
1 490 VAL n 
1 491 ILE n 
1 492 ALA n 
1 493 TRP n 
1 494 ILE n 
1 495 TYR n 
1 496 GLY n 
1 497 GLY n 
1 498 ASP n 
1 499 ASN n 
1 500 LEU n 
1 501 TYR n 
1 502 ASP n 
1 503 GLY n 
1 504 ILE n 
1 505 GLU n 
1 506 ASP n 
1 507 MET n 
1 508 ILE n 
1 509 GLY n 
1 510 TYR n 
1 511 ARG n 
1 512 PRO n 
1 513 GLY n 
1 514 PRO n 
1 515 TRP n 
1 516 MET n 
1 517 LYS n 
1 518 TYR n 
1 519 SER n 
1 520 TRP n 
1 521 ALA n 
1 522 VAL n 
1 523 ILE n 
1 524 THR n 
1 525 PRO n 
1 526 VAL n 
1 527 LEU n 
1 528 CYS n 
1 529 VAL n 
1 530 GLY n 
1 531 CYS n 
1 532 PHE n 
1 533 ILE n 
1 534 PHE n 
1 535 SER n 
1 536 LEU n 
1 537 VAL n 
1 538 LYS n 
1 539 TYR n 
1 540 VAL n 
1 541 PRO n 
1 542 LEU n 
1 543 THR n 
1 544 TYR n 
1 545 ASN n 
1 546 LYS n 
1 547 THR n 
1 548 TYR n 
1 549 VAL n 
1 550 TYR n 
1 551 PRO n 
1 552 ASN n 
1 553 TRP n 
1 554 ALA n 
1 555 ILE n 
1 556 GLY n 
1 557 LEU n 
1 558 GLY n 
1 559 TRP n 
1 560 SER n 
1 561 LEU n 
1 562 ALA n 
1 563 LEU n 
1 564 SER n 
1 565 SER n 
1 566 MET n 
1 567 LEU n 
1 568 CYS n 
1 569 VAL n 
1 570 PRO n 
1 571 LEU n 
1 572 VAL n 
1 573 ILE n 
1 574 VAL n 
1 575 ILE n 
1 576 ARG n 
1 577 LEU n 
1 578 CYS n 
1 579 GLN n 
1 580 THR n 
1 581 GLU n 
1 582 GLY n 
1 583 PRO n 
1 584 PHE n 
1 585 LEU n 
1 586 VAL n 
1 587 ARG n 
1 588 VAL n 
1 589 LYS n 
1 590 TYR n 
1 591 LEU n 
1 592 LEU n 
1 593 THR n 
1 594 PRO n 
1 595 ARG n 
1 596 GLU n 
1 597 PRO n 
1 598 ASN n 
1 599 ARG n 
1 600 TRP n 
1 601 ALA n 
1 602 VAL n 
1 603 GLU n 
1 604 ARG n 
1 605 GLU n 
1 606 GLY n 
1 607 ALA n 
1 608 THR n 
1 609 PRO n 
1 610 TYR n 
1 611 ASN n 
1 612 SER n 
1 613 ARG n 
1 614 THR n 
1 615 VAL n 
1 616 MET n 
1 617 ASN n 
1 618 GLY n 
1 619 ALA n 
1 620 LEU n 
1 621 VAL n 
1 622 LYS n 
1 623 PRO n 
1 624 THR n 
1 625 HIS n 
1 626 ILE n 
1 627 ILE n 
1 628 VAL n 
1 629 GLU n 
1 630 THR n 
1 631 MET n 
1 632 MET n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   632 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 SLC6A6 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                      ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                     ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                   ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'              ? 'C4 H7 N O4'     133.103 
CL  non-polymer         . 'CHLORIDE ION'               ? 'Cl -1'          35.453  
CYS 'L-peptide linking' y CYSTEINE                     ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                    ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'              ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                      ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                    ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE                   ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                      ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                       ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                   ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                      ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                       ? 'C3 H7 N O3'     105.093 
TAU non-polymer         . '2-AMINOETHANESULFONIC ACID' ? 'C2 H7 N O3 S'   125.147 
THR 'L-peptide linking' y THREONINE                    ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                   ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                     ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                       ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -11 ?   ?   ?   A . n 
A 1 2   ASP 2   -10 ?   ?   ?   A . n 
A 1 3   TYR 3   -9  ?   ?   ?   A . n 
A 1 4   LYS 4   -8  ?   ?   ?   A . n 
A 1 5   ASP 5   -7  ?   ?   ?   A . n 
A 1 6   ASP 6   -6  ?   ?   ?   A . n 
A 1 7   ASP 7   -5  ?   ?   ?   A . n 
A 1 8   ASP 8   -4  ?   ?   ?   A . n 
A 1 9   LYS 9   -3  ?   ?   ?   A . n 
A 1 10  GLY 10  -2  ?   ?   ?   A . n 
A 1 11  SER 11  -1  ?   ?   ?   A . n 
A 1 12  GLY 12  0   ?   ?   ?   A . n 
A 1 13  MET 13  1   ?   ?   ?   A . n 
A 1 14  ALA 14  2   ?   ?   ?   A . n 
A 1 15  THR 15  3   ?   ?   ?   A . n 
A 1 16  LYS 16  4   ?   ?   ?   A . n 
A 1 17  GLU 17  5   ?   ?   ?   A . n 
A 1 18  LYS 18  6   ?   ?   ?   A . n 
A 1 19  LEU 19  7   ?   ?   ?   A . n 
A 1 20  GLN 20  8   ?   ?   ?   A . n 
A 1 21  CYS 21  9   ?   ?   ?   A . n 
A 1 22  LEU 22  10  ?   ?   ?   A . n 
A 1 23  LYS 23  11  ?   ?   ?   A . n 
A 1 24  ASP 24  12  ?   ?   ?   A . n 
A 1 25  PHE 25  13  ?   ?   ?   A . n 
A 1 26  HIS 26  14  ?   ?   ?   A . n 
A 1 27  LYS 27  15  ?   ?   ?   A . n 
A 1 28  ASP 28  16  ?   ?   ?   A . n 
A 1 29  ILE 29  17  ?   ?   ?   A . n 
A 1 30  LEU 30  18  ?   ?   ?   A . n 
A 1 31  LYS 31  19  ?   ?   ?   A . n 
A 1 32  PRO 32  20  ?   ?   ?   A . n 
A 1 33  SER 33  21  ?   ?   ?   A . n 
A 1 34  PRO 34  22  ?   ?   ?   A . n 
A 1 35  GLY 35  23  ?   ?   ?   A . n 
A 1 36  LYS 36  24  ?   ?   ?   A . n 
A 1 37  SER 37  25  ?   ?   ?   A . n 
A 1 38  PRO 38  26  ?   ?   ?   A . n 
A 1 39  GLY 39  27  ?   ?   ?   A . n 
A 1 40  THR 40  28  ?   ?   ?   A . n 
A 1 41  ARG 41  29  ?   ?   ?   A . n 
A 1 42  PRO 42  30  ?   ?   ?   A . n 
A 1 43  GLU 43  31  ?   ?   ?   A . n 
A 1 44  ASP 44  32  ?   ?   ?   A . n 
A 1 45  GLU 45  33  ?   ?   ?   A . n 
A 1 46  ALA 46  34  ?   ?   ?   A . n 
A 1 47  GLU 47  35  ?   ?   ?   A . n 
A 1 48  GLY 48  36  ?   ?   ?   A . n 
A 1 49  LYS 49  37  ?   ?   ?   A . n 
A 1 50  PRO 50  38  ?   ?   ?   A . n 
A 1 51  PRO 51  39  39  PRO PRO A . n 
A 1 52  GLN 52  40  40  GLN GLN A . n 
A 1 53  ARG 53  41  41  ARG ARG A . n 
A 1 54  GLU 54  42  42  GLU GLU A . n 
A 1 55  LYS 55  43  43  LYS LYS A . n 
A 1 56  TRP 56  44  44  TRP TRP A . n 
A 1 57  SER 57  45  45  SER SER A . n 
A 1 58  SER 58  46  46  SER SER A . n 
A 1 59  LYS 59  47  47  LYS LYS A . n 
A 1 60  ILE 60  48  48  ILE ILE A . n 
A 1 61  ASP 61  49  49  ASP ASP A . n 
A 1 62  PHE 62  50  50  PHE PHE A . n 
A 1 63  VAL 63  51  51  VAL VAL A . n 
A 1 64  LEU 64  52  52  LEU LEU A . n 
A 1 65  SER 65  53  53  SER SER A . n 
A 1 66  VAL 66  54  54  VAL VAL A . n 
A 1 67  ALA 67  55  55  ALA ALA A . n 
A 1 68  GLY 68  56  56  GLY GLY A . n 
A 1 69  GLY 69  57  57  GLY GLY A . n 
A 1 70  PHE 70  58  58  PHE PHE A . n 
A 1 71  VAL 71  59  59  VAL VAL A . n 
A 1 72  GLY 72  60  60  GLY GLY A . n 
A 1 73  LEU 73  61  61  LEU LEU A . n 
A 1 74  GLY 74  62  62  GLY GLY A . n 
A 1 75  ASN 75  63  63  ASN ASN A . n 
A 1 76  VAL 76  64  64  VAL VAL A . n 
A 1 77  TRP 77  65  65  TRP TRP A . n 
A 1 78  ARG 78  66  66  ARG ARG A . n 
A 1 79  PHE 79  67  67  PHE PHE A . n 
A 1 80  PRO 80  68  68  PRO PRO A . n 
A 1 81  TYR 81  69  69  TYR TYR A . n 
A 1 82  LEU 82  70  70  LEU LEU A . n 
A 1 83  CYS 83  71  71  CYS CYS A . n 
A 1 84  TYR 84  72  72  TYR TYR A . n 
A 1 85  LYS 85  73  73  LYS LYS A . n 
A 1 86  ASN 86  74  74  ASN ASN A . n 
A 1 87  GLY 87  75  75  GLY GLY A . n 
A 1 88  GLY 88  76  76  GLY GLY A . n 
A 1 89  GLY 89  77  77  GLY GLY A . n 
A 1 90  ALA 90  78  78  ALA ALA A . n 
A 1 91  PHE 91  79  79  PHE PHE A . n 
A 1 92  LEU 92  80  80  LEU LEU A . n 
A 1 93  ILE 93  81  81  ILE ILE A . n 
A 1 94  PRO 94  82  82  PRO PRO A . n 
A 1 95  TYR 95  83  83  TYR TYR A . n 
A 1 96  PHE 96  84  84  PHE PHE A . n 
A 1 97  ILE 97  85  85  ILE ILE A . n 
A 1 98  PHE 98  86  86  PHE PHE A . n 
A 1 99  LEU 99  87  87  LEU LEU A . n 
A 1 100 PHE 100 88  88  PHE PHE A . n 
A 1 101 GLY 101 89  89  GLY GLY A . n 
A 1 102 SER 102 90  90  SER SER A . n 
A 1 103 GLY 103 91  91  GLY GLY A . n 
A 1 104 LEU 104 92  92  LEU LEU A . n 
A 1 105 PRO 105 93  93  PRO PRO A . n 
A 1 106 VAL 106 94  94  VAL VAL A . n 
A 1 107 PHE 107 95  95  PHE PHE A . n 
A 1 108 PHE 108 96  96  PHE PHE A . n 
A 1 109 LEU 109 97  97  LEU LEU A . n 
A 1 110 GLU 110 98  98  GLU GLU A . n 
A 1 111 ILE 111 99  99  ILE ILE A . n 
A 1 112 ILE 112 100 100 ILE ILE A . n 
A 1 113 ILE 113 101 101 ILE ILE A . n 
A 1 114 GLY 114 102 102 GLY GLY A . n 
A 1 115 GLN 115 103 103 GLN GLN A . n 
A 1 116 TYR 116 104 104 TYR TYR A . n 
A 1 117 THR 117 105 105 THR THR A . n 
A 1 118 SER 118 106 106 SER SER A . n 
A 1 119 GLU 119 107 107 GLU GLU A . n 
A 1 120 GLY 120 108 108 GLY GLY A . n 
A 1 121 GLY 121 109 109 GLY GLY A . n 
A 1 122 ILE 122 110 110 ILE ILE A . n 
A 1 123 THR 123 111 111 THR THR A . n 
A 1 124 CYS 124 112 112 CYS CYS A . n 
A 1 125 TRP 125 113 113 TRP TRP A . n 
A 1 126 GLU 126 114 114 GLU GLU A . n 
A 1 127 LYS 127 115 115 LYS LYS A . n 
A 1 128 ILE 128 116 116 ILE ILE A . n 
A 1 129 CYS 129 117 117 CYS CYS A . n 
A 1 130 PRO 130 118 118 PRO PRO A . n 
A 1 131 LEU 131 119 119 LEU LEU A . n 
A 1 132 PHE 132 120 120 PHE PHE A . n 
A 1 133 SER 133 121 121 SER SER A . n 
A 1 134 GLY 134 122 122 GLY GLY A . n 
A 1 135 ILE 135 123 123 ILE ILE A . n 
A 1 136 GLY 136 124 124 GLY GLY A . n 
A 1 137 TYR 137 125 125 TYR TYR A . n 
A 1 138 ALA 138 126 126 ALA ALA A . n 
A 1 139 SER 139 127 127 SER SER A . n 
A 1 140 VAL 140 128 128 VAL VAL A . n 
A 1 141 VAL 141 129 129 VAL VAL A . n 
A 1 142 ILE 142 130 130 ILE ILE A . n 
A 1 143 VAL 143 131 131 VAL VAL A . n 
A 1 144 SER 144 132 132 SER SER A . n 
A 1 145 LEU 145 133 133 LEU LEU A . n 
A 1 146 LEU 146 134 134 LEU LEU A . n 
A 1 147 ASN 147 135 135 ASN ASN A . n 
A 1 148 VAL 148 136 136 VAL VAL A . n 
A 1 149 TYR 149 137 137 TYR TYR A . n 
A 1 150 TYR 150 138 138 TYR TYR A . n 
A 1 151 ILE 151 139 139 ILE ILE A . n 
A 1 152 VAL 152 140 140 VAL VAL A . n 
A 1 153 ILE 153 141 141 ILE ILE A . n 
A 1 154 LEU 154 142 142 LEU LEU A . n 
A 1 155 ALA 155 143 143 ALA ALA A . n 
A 1 156 TRP 156 144 144 TRP TRP A . n 
A 1 157 ALA 157 145 145 ALA ALA A . n 
A 1 158 THR 158 146 146 THR THR A . n 
A 1 159 TYR 159 147 147 TYR TYR A . n 
A 1 160 TYR 160 148 148 TYR TYR A . n 
A 1 161 LEU 161 149 149 LEU LEU A . n 
A 1 162 PHE 162 150 150 PHE PHE A . n 
A 1 163 GLN 163 151 151 GLN GLN A . n 
A 1 164 SER 164 152 152 SER SER A . n 
A 1 165 PHE 165 153 153 PHE PHE A . n 
A 1 166 GLN 166 154 154 GLN GLN A . n 
A 1 167 LYS 167 155 155 LYS LYS A . n 
A 1 168 GLU 168 156 156 GLU GLU A . n 
A 1 169 LEU 169 157 157 LEU LEU A . n 
A 1 170 PRO 170 158 158 PRO PRO A . n 
A 1 171 TRP 171 159 159 TRP TRP A . n 
A 1 172 ALA 172 160 160 ALA ALA A . n 
A 1 173 HIS 173 161 161 HIS HIS A . n 
A 1 174 CYS 174 162 162 CYS CYS A . n 
A 1 175 ASN 175 163 163 ASN ASN A . n 
A 1 176 HIS 176 164 164 HIS HIS A . n 
A 1 177 SER 177 165 165 SER SER A . n 
A 1 178 TRP 178 166 166 TRP TRP A . n 
A 1 179 ASN 179 167 167 ASN ASN A . n 
A 1 180 THR 180 168 168 THR THR A . n 
A 1 181 PRO 181 169 169 PRO PRO A . n 
A 1 182 HIS 182 170 170 HIS HIS A . n 
A 1 183 CYS 183 171 171 CYS CYS A . n 
A 1 184 MET 184 172 172 MET MET A . n 
A 1 185 GLU 185 173 173 GLU GLU A . n 
A 1 186 ASP 186 174 174 ASP ASP A . n 
A 1 187 THR 187 175 175 THR THR A . n 
A 1 188 MET 188 176 176 MET MET A . n 
A 1 189 ARG 189 177 177 ARG ARG A . n 
A 1 190 LYS 190 178 178 LYS LYS A . n 
A 1 191 ASN 191 179 179 ASN ASN A . n 
A 1 192 LYS 192 180 180 LYS LYS A . n 
A 1 193 SER 193 181 181 SER SER A . n 
A 1 194 VAL 194 182 182 VAL VAL A . n 
A 1 195 TRP 195 183 183 TRP TRP A . n 
A 1 196 ILE 196 184 184 ILE ILE A . n 
A 1 197 THR 197 185 185 THR THR A . n 
A 1 198 ILE 198 186 186 ILE ILE A . n 
A 1 199 SER 199 187 187 SER SER A . n 
A 1 200 SER 200 188 188 SER SER A . n 
A 1 201 THR 201 189 189 THR THR A . n 
A 1 202 ASN 202 190 190 ASN ASN A . n 
A 1 203 PHE 203 191 191 PHE PHE A . n 
A 1 204 THR 204 192 192 THR THR A . n 
A 1 205 SER 205 193 193 SER SER A . n 
A 1 206 PRO 206 194 194 PRO PRO A . n 
A 1 207 VAL 207 195 195 VAL VAL A . n 
A 1 208 ILE 208 196 196 ILE ILE A . n 
A 1 209 GLU 209 197 197 GLU GLU A . n 
A 1 210 PHE 210 198 198 PHE PHE A . n 
A 1 211 TRP 211 199 199 TRP TRP A . n 
A 1 212 GLU 212 200 200 GLU GLU A . n 
A 1 213 ARG 213 201 201 ARG ARG A . n 
A 1 214 ASN 214 202 202 ASN ASN A . n 
A 1 215 VAL 215 203 203 VAL VAL A . n 
A 1 216 LEU 216 204 204 LEU LEU A . n 
A 1 217 SER 217 205 205 SER SER A . n 
A 1 218 LEU 218 206 206 LEU LEU A . n 
A 1 219 SER 219 207 207 SER SER A . n 
A 1 220 PRO 220 208 208 PRO PRO A . n 
A 1 221 GLY 221 209 209 GLY GLY A . n 
A 1 222 ILE 222 210 210 ILE ILE A . n 
A 1 223 ASP 223 211 211 ASP ASP A . n 
A 1 224 HIS 224 212 212 HIS HIS A . n 
A 1 225 PRO 225 213 213 PRO PRO A . n 
A 1 226 GLY 226 214 214 GLY GLY A . n 
A 1 227 SER 227 215 215 SER SER A . n 
A 1 228 LEU 228 216 216 LEU LEU A . n 
A 1 229 LYS 229 217 217 LYS LYS A . n 
A 1 230 TRP 230 218 218 TRP TRP A . n 
A 1 231 ASP 231 219 219 ASP ASP A . n 
A 1 232 LEU 232 220 220 LEU LEU A . n 
A 1 233 ALA 233 221 221 ALA ALA A . n 
A 1 234 LEU 234 222 222 LEU LEU A . n 
A 1 235 CYS 235 223 223 CYS CYS A . n 
A 1 236 LEU 236 224 224 LEU LEU A . n 
A 1 237 LEU 237 225 225 LEU LEU A . n 
A 1 238 LEU 238 226 226 LEU LEU A . n 
A 1 239 VAL 239 227 227 VAL VAL A . n 
A 1 240 TRP 240 228 228 TRP TRP A . n 
A 1 241 LEU 241 229 229 LEU LEU A . n 
A 1 242 VAL 242 230 230 VAL VAL A . n 
A 1 243 CYS 243 231 231 CYS CYS A . n 
A 1 244 PHE 244 232 232 PHE PHE A . n 
A 1 245 PHE 245 233 233 PHE PHE A . n 
A 1 246 CYS 246 234 234 CYS CYS A . n 
A 1 247 ILE 247 235 235 ILE ILE A . n 
A 1 248 TRP 248 236 236 TRP TRP A . n 
A 1 249 LYS 249 237 237 LYS LYS A . n 
A 1 250 GLY 250 238 238 GLY GLY A . n 
A 1 251 VAL 251 239 239 VAL VAL A . n 
A 1 252 ARG 252 240 240 ARG ARG A . n 
A 1 253 SER 253 241 241 SER SER A . n 
A 1 254 THR 254 242 242 THR THR A . n 
A 1 255 GLY 255 243 243 GLY GLY A . n 
A 1 256 LYS 256 244 244 LYS LYS A . n 
A 1 257 VAL 257 245 245 VAL VAL A . n 
A 1 258 VAL 258 246 246 VAL VAL A . n 
A 1 259 TYR 259 247 247 TYR TYR A . n 
A 1 260 PHE 260 248 248 PHE PHE A . n 
A 1 261 THR 261 249 249 THR THR A . n 
A 1 262 ALA 262 250 250 ALA ALA A . n 
A 1 263 THR 263 251 251 THR THR A . n 
A 1 264 PHE 264 252 252 PHE PHE A . n 
A 1 265 PRO 265 253 253 PRO PRO A . n 
A 1 266 PHE 266 254 254 PHE PHE A . n 
A 1 267 ALA 267 255 255 ALA ALA A . n 
A 1 268 MET 268 256 256 MET MET A . n 
A 1 269 LEU 269 257 257 LEU LEU A . n 
A 1 270 LEU 270 258 258 LEU LEU A . n 
A 1 271 VAL 271 259 259 VAL VAL A . n 
A 1 272 LEU 272 260 260 LEU LEU A . n 
A 1 273 LEU 273 261 261 LEU LEU A . n 
A 1 274 VAL 274 262 262 VAL VAL A . n 
A 1 275 ARG 275 263 263 ARG ARG A . n 
A 1 276 GLY 276 264 264 GLY GLY A . n 
A 1 277 LEU 277 265 265 LEU LEU A . n 
A 1 278 THR 278 266 266 THR THR A . n 
A 1 279 LEU 279 267 267 LEU LEU A . n 
A 1 280 PRO 280 268 268 PRO PRO A . n 
A 1 281 GLY 281 269 269 GLY GLY A . n 
A 1 282 ALA 282 270 270 ALA ALA A . n 
A 1 283 GLY 283 271 271 GLY GLY A . n 
A 1 284 ALA 284 272 272 ALA ALA A . n 
A 1 285 GLY 285 273 273 GLY GLY A . n 
A 1 286 ILE 286 274 274 ILE ILE A . n 
A 1 287 LYS 287 275 275 LYS LYS A . n 
A 1 288 PHE 288 276 276 PHE PHE A . n 
A 1 289 TYR 289 277 277 TYR TYR A . n 
A 1 290 LEU 290 278 278 LEU LEU A . n 
A 1 291 TYR 291 279 279 TYR TYR A . n 
A 1 292 PRO 292 280 280 PRO PRO A . n 
A 1 293 ASP 293 281 281 ASP ASP A . n 
A 1 294 ILE 294 282 282 ILE ILE A . n 
A 1 295 THR 295 283 283 THR THR A . n 
A 1 296 ARG 296 284 284 ARG ARG A . n 
A 1 297 LEU 297 285 285 LEU LEU A . n 
A 1 298 GLU 298 286 286 GLU GLU A . n 
A 1 299 ASP 299 287 287 ASP ASP A . n 
A 1 300 PRO 300 288 288 PRO PRO A . n 
A 1 301 GLN 301 289 289 GLN GLN A . n 
A 1 302 VAL 302 290 290 VAL VAL A . n 
A 1 303 TRP 303 291 291 TRP TRP A . n 
A 1 304 ILE 304 292 292 ILE ILE A . n 
A 1 305 ASP 305 293 293 ASP ASP A . n 
A 1 306 ALA 306 294 294 ALA ALA A . n 
A 1 307 GLY 307 295 295 GLY GLY A . n 
A 1 308 THR 308 296 296 THR THR A . n 
A 1 309 GLN 309 297 297 GLN GLN A . n 
A 1 310 ILE 310 298 298 ILE ILE A . n 
A 1 311 PHE 311 299 299 PHE PHE A . n 
A 1 312 PHE 312 300 300 PHE PHE A . n 
A 1 313 SER 313 301 301 SER SER A . n 
A 1 314 TYR 314 302 302 TYR TYR A . n 
A 1 315 ALA 315 303 303 ALA ALA A . n 
A 1 316 ILE 316 304 304 ILE ILE A . n 
A 1 317 CYS 317 305 305 CYS CYS A . n 
A 1 318 LEU 318 306 306 LEU LEU A . n 
A 1 319 GLY 319 307 307 GLY GLY A . n 
A 1 320 ALA 320 308 308 ALA ALA A . n 
A 1 321 MET 321 309 309 MET MET A . n 
A 1 322 THR 322 310 310 THR THR A . n 
A 1 323 SER 323 311 311 SER SER A . n 
A 1 324 LEU 324 312 312 LEU LEU A . n 
A 1 325 GLY 325 313 313 GLY GLY A . n 
A 1 326 SER 326 314 314 SER SER A . n 
A 1 327 TYR 327 315 315 TYR TYR A . n 
A 1 328 ASN 328 316 316 ASN ASN A . n 
A 1 329 LYS 329 317 317 LYS LYS A . n 
A 1 330 TYR 330 318 318 TYR TYR A . n 
A 1 331 LYS 331 319 319 LYS LYS A . n 
A 1 332 TYR 332 320 320 TYR TYR A . n 
A 1 333 ASN 333 321 321 ASN ASN A . n 
A 1 334 SER 334 322 322 SER SER A . n 
A 1 335 TYR 335 323 323 TYR TYR A . n 
A 1 336 ARG 336 324 324 ARG ARG A . n 
A 1 337 ASP 337 325 325 ASP ASP A . n 
A 1 338 CYS 338 326 326 CYS CYS A . n 
A 1 339 MET 339 327 327 MET MET A . n 
A 1 340 LEU 340 328 328 LEU LEU A . n 
A 1 341 LEU 341 329 329 LEU LEU A . n 
A 1 342 GLY 342 330 330 GLY GLY A . n 
A 1 343 CYS 343 331 331 CYS CYS A . n 
A 1 344 LEU 344 332 332 LEU LEU A . n 
A 1 345 ASN 345 333 333 ASN ASN A . n 
A 1 346 SER 346 334 334 SER SER A . n 
A 1 347 GLY 347 335 335 GLY GLY A . n 
A 1 348 THR 348 336 336 THR THR A . n 
A 1 349 SER 349 337 337 SER SER A . n 
A 1 350 PHE 350 338 338 PHE PHE A . n 
A 1 351 VAL 351 339 339 VAL VAL A . n 
A 1 352 SER 352 340 340 SER SER A . n 
A 1 353 GLY 353 341 341 GLY GLY A . n 
A 1 354 PHE 354 342 342 PHE PHE A . n 
A 1 355 ALA 355 343 343 ALA ALA A . n 
A 1 356 ILE 356 344 344 ILE ILE A . n 
A 1 357 PHE 357 345 345 PHE PHE A . n 
A 1 358 SER 358 346 346 SER SER A . n 
A 1 359 ILE 359 347 347 ILE ILE A . n 
A 1 360 LEU 360 348 348 LEU LEU A . n 
A 1 361 GLY 361 349 349 GLY GLY A . n 
A 1 362 PHE 362 350 350 PHE PHE A . n 
A 1 363 MET 363 351 351 MET MET A . n 
A 1 364 ALA 364 352 352 ALA ALA A . n 
A 1 365 GLN 365 353 353 GLN GLN A . n 
A 1 366 GLU 366 354 354 GLU GLU A . n 
A 1 367 GLN 367 355 355 GLN GLN A . n 
A 1 368 GLY 368 356 356 GLY GLY A . n 
A 1 369 VAL 369 357 357 VAL VAL A . n 
A 1 370 ASP 370 358 358 ASP ASP A . n 
A 1 371 ILE 371 359 359 ILE ILE A . n 
A 1 372 ALA 372 360 360 ALA ALA A . n 
A 1 373 ASP 373 361 361 ASP ASP A . n 
A 1 374 VAL 374 362 362 VAL VAL A . n 
A 1 375 ALA 375 363 363 ALA ALA A . n 
A 1 376 GLU 376 364 364 GLU GLU A . n 
A 1 377 SER 377 365 365 SER SER A . n 
A 1 378 GLY 378 366 366 GLY GLY A . n 
A 1 379 PRO 379 367 367 PRO PRO A . n 
A 1 380 GLY 380 368 368 GLY GLY A . n 
A 1 381 LEU 381 369 369 LEU LEU A . n 
A 1 382 ALA 382 370 370 ALA ALA A . n 
A 1 383 PHE 383 371 371 PHE PHE A . n 
A 1 384 ILE 384 372 372 ILE ILE A . n 
A 1 385 ALA 385 373 373 ALA ALA A . n 
A 1 386 TYR 386 374 374 TYR TYR A . n 
A 1 387 PRO 387 375 375 PRO PRO A . n 
A 1 388 LYS 388 376 376 LYS LYS A . n 
A 1 389 ALA 389 377 377 ALA ALA A . n 
A 1 390 VAL 390 378 378 VAL VAL A . n 
A 1 391 THR 391 379 379 THR THR A . n 
A 1 392 MET 392 380 380 MET MET A . n 
A 1 393 MET 393 381 381 MET MET A . n 
A 1 394 PRO 394 382 382 PRO PRO A . n 
A 1 395 LEU 395 383 383 LEU LEU A . n 
A 1 396 PRO 396 384 384 PRO PRO A . n 
A 1 397 THR 397 385 385 THR THR A . n 
A 1 398 PHE 398 386 386 PHE PHE A . n 
A 1 399 TRP 399 387 387 TRP TRP A . n 
A 1 400 SER 400 388 388 SER SER A . n 
A 1 401 ILE 401 389 389 ILE ILE A . n 
A 1 402 LEU 402 390 390 LEU LEU A . n 
A 1 403 PHE 403 391 391 PHE PHE A . n 
A 1 404 PHE 404 392 392 PHE PHE A . n 
A 1 405 ILE 405 393 393 ILE ILE A . n 
A 1 406 MET 406 394 394 MET MET A . n 
A 1 407 LEU 407 395 395 LEU LEU A . n 
A 1 408 LEU 408 396 396 LEU LEU A . n 
A 1 409 LEU 409 397 397 LEU LEU A . n 
A 1 410 LEU 410 398 398 LEU LEU A . n 
A 1 411 GLY 411 399 399 GLY GLY A . n 
A 1 412 LEU 412 400 400 LEU LEU A . n 
A 1 413 ASP 413 401 401 ASP ASP A . n 
A 1 414 SER 414 402 402 SER SER A . n 
A 1 415 GLN 415 403 403 GLN GLN A . n 
A 1 416 PHE 416 404 404 PHE PHE A . n 
A 1 417 VAL 417 405 405 VAL VAL A . n 
A 1 418 GLU 418 406 406 GLU GLU A . n 
A 1 419 VAL 419 407 407 VAL VAL A . n 
A 1 420 GLU 420 408 408 GLU GLU A . n 
A 1 421 GLY 421 409 409 GLY GLY A . n 
A 1 422 GLN 422 410 410 GLN GLN A . n 
A 1 423 ILE 423 411 411 ILE ILE A . n 
A 1 424 THR 424 412 412 THR THR A . n 
A 1 425 SER 425 413 413 SER SER A . n 
A 1 426 LEU 426 414 414 LEU LEU A . n 
A 1 427 VAL 427 415 415 VAL VAL A . n 
A 1 428 ASP 428 416 416 ASP ASP A . n 
A 1 429 LEU 429 417 417 LEU LEU A . n 
A 1 430 TYR 430 418 418 TYR TYR A . n 
A 1 431 PRO 431 419 419 PRO PRO A . n 
A 1 432 SER 432 420 420 SER SER A . n 
A 1 433 PHE 433 421 421 PHE PHE A . n 
A 1 434 LEU 434 422 422 LEU LEU A . n 
A 1 435 ARG 435 423 423 ARG ARG A . n 
A 1 436 LYS 436 424 424 LYS LYS A . n 
A 1 437 GLY 437 425 425 GLY GLY A . n 
A 1 438 TYR 438 426 426 TYR TYR A . n 
A 1 439 ARG 439 427 427 ARG ARG A . n 
A 1 440 ARG 440 428 428 ARG ARG A . n 
A 1 441 GLU 441 429 429 GLU GLU A . n 
A 1 442 ILE 442 430 430 ILE ILE A . n 
A 1 443 PHE 443 431 431 PHE PHE A . n 
A 1 444 ILE 444 432 432 ILE ILE A . n 
A 1 445 ALA 445 433 433 ALA ALA A . n 
A 1 446 PHE 446 434 434 PHE PHE A . n 
A 1 447 VAL 447 435 435 VAL VAL A . n 
A 1 448 CYS 448 436 436 CYS CYS A . n 
A 1 449 SER 449 437 437 SER SER A . n 
A 1 450 ILE 450 438 438 ILE ILE A . n 
A 1 451 SER 451 439 439 SER SER A . n 
A 1 452 TYR 452 440 440 TYR TYR A . n 
A 1 453 LEU 453 441 441 LEU LEU A . n 
A 1 454 LEU 454 442 442 LEU LEU A . n 
A 1 455 GLY 455 443 443 GLY GLY A . n 
A 1 456 LEU 456 444 444 LEU LEU A . n 
A 1 457 THR 457 445 445 THR THR A . n 
A 1 458 MET 458 446 446 MET MET A . n 
A 1 459 VAL 459 447 447 VAL VAL A . n 
A 1 460 THR 460 448 448 THR THR A . n 
A 1 461 GLU 461 449 449 GLU GLU A . n 
A 1 462 GLY 462 450 450 GLY GLY A . n 
A 1 463 GLY 463 451 451 GLY GLY A . n 
A 1 464 MET 464 452 452 MET MET A . n 
A 1 465 TYR 465 453 453 TYR TYR A . n 
A 1 466 VAL 466 454 454 VAL VAL A . n 
A 1 467 PHE 467 455 455 PHE PHE A . n 
A 1 468 GLN 468 456 456 GLN GLN A . n 
A 1 469 LEU 469 457 457 LEU LEU A . n 
A 1 470 PHE 470 458 458 PHE PHE A . n 
A 1 471 ASP 471 459 459 ASP ASP A . n 
A 1 472 TYR 472 460 460 TYR TYR A . n 
A 1 473 TYR 473 461 461 TYR TYR A . n 
A 1 474 ALA 474 462 462 ALA ALA A . n 
A 1 475 ALA 475 463 463 ALA ALA A . n 
A 1 476 SER 476 464 464 SER SER A . n 
A 1 477 GLY 477 465 465 GLY GLY A . n 
A 1 478 VAL 478 466 466 VAL VAL A . n 
A 1 479 CYS 479 467 467 CYS CYS A . n 
A 1 480 LEU 480 468 468 LEU LEU A . n 
A 1 481 LEU 481 469 469 LEU LEU A . n 
A 1 482 TRP 482 470 470 TRP TRP A . n 
A 1 483 VAL 483 471 471 VAL VAL A . n 
A 1 484 ALA 484 472 472 ALA ALA A . n 
A 1 485 PHE 485 473 473 PHE PHE A . n 
A 1 486 PHE 486 474 474 PHE PHE A . n 
A 1 487 GLU 487 475 475 GLU GLU A . n 
A 1 488 CYS 488 476 476 CYS CYS A . n 
A 1 489 PHE 489 477 477 PHE PHE A . n 
A 1 490 VAL 490 478 478 VAL VAL A . n 
A 1 491 ILE 491 479 479 ILE ILE A . n 
A 1 492 ALA 492 480 480 ALA ALA A . n 
A 1 493 TRP 493 481 481 TRP TRP A . n 
A 1 494 ILE 494 482 482 ILE ILE A . n 
A 1 495 TYR 495 483 483 TYR TYR A . n 
A 1 496 GLY 496 484 484 GLY GLY A . n 
A 1 497 GLY 497 485 485 GLY GLY A . n 
A 1 498 ASP 498 486 486 ASP ASP A . n 
A 1 499 ASN 499 487 487 ASN ASN A . n 
A 1 500 LEU 500 488 488 LEU LEU A . n 
A 1 501 TYR 501 489 489 TYR TYR A . n 
A 1 502 ASP 502 490 490 ASP ASP A . n 
A 1 503 GLY 503 491 491 GLY GLY A . n 
A 1 504 ILE 504 492 492 ILE ILE A . n 
A 1 505 GLU 505 493 493 GLU GLU A . n 
A 1 506 ASP 506 494 494 ASP ASP A . n 
A 1 507 MET 507 495 495 MET MET A . n 
A 1 508 ILE 508 496 496 ILE ILE A . n 
A 1 509 GLY 509 497 497 GLY GLY A . n 
A 1 510 TYR 510 498 498 TYR TYR A . n 
A 1 511 ARG 511 499 499 ARG ARG A . n 
A 1 512 PRO 512 500 500 PRO PRO A . n 
A 1 513 GLY 513 501 501 GLY GLY A . n 
A 1 514 PRO 514 502 502 PRO PRO A . n 
A 1 515 TRP 515 503 503 TRP TRP A . n 
A 1 516 MET 516 504 504 MET MET A . n 
A 1 517 LYS 517 505 505 LYS LYS A . n 
A 1 518 TYR 518 506 506 TYR TYR A . n 
A 1 519 SER 519 507 507 SER SER A . n 
A 1 520 TRP 520 508 508 TRP TRP A . n 
A 1 521 ALA 521 509 509 ALA ALA A . n 
A 1 522 VAL 522 510 510 VAL VAL A . n 
A 1 523 ILE 523 511 511 ILE ILE A . n 
A 1 524 THR 524 512 512 THR THR A . n 
A 1 525 PRO 525 513 513 PRO PRO A . n 
A 1 526 VAL 526 514 514 VAL VAL A . n 
A 1 527 LEU 527 515 515 LEU LEU A . n 
A 1 528 CYS 528 516 516 CYS CYS A . n 
A 1 529 VAL 529 517 517 VAL VAL A . n 
A 1 530 GLY 530 518 518 GLY GLY A . n 
A 1 531 CYS 531 519 519 CYS CYS A . n 
A 1 532 PHE 532 520 520 PHE PHE A . n 
A 1 533 ILE 533 521 521 ILE ILE A . n 
A 1 534 PHE 534 522 522 PHE PHE A . n 
A 1 535 SER 535 523 523 SER SER A . n 
A 1 536 LEU 536 524 524 LEU LEU A . n 
A 1 537 VAL 537 525 525 VAL VAL A . n 
A 1 538 LYS 538 526 526 LYS LYS A . n 
A 1 539 TYR 539 527 527 TYR TYR A . n 
A 1 540 VAL 540 528 528 VAL VAL A . n 
A 1 541 PRO 541 529 529 PRO PRO A . n 
A 1 542 LEU 542 530 530 LEU LEU A . n 
A 1 543 THR 543 531 531 THR THR A . n 
A 1 544 TYR 544 532 532 TYR TYR A . n 
A 1 545 ASN 545 533 533 ASN ASN A . n 
A 1 546 LYS 546 534 534 LYS LYS A . n 
A 1 547 THR 547 535 535 THR THR A . n 
A 1 548 TYR 548 536 536 TYR TYR A . n 
A 1 549 VAL 549 537 537 VAL VAL A . n 
A 1 550 TYR 550 538 538 TYR TYR A . n 
A 1 551 PRO 551 539 539 PRO PRO A . n 
A 1 552 ASN 552 540 540 ASN ASN A . n 
A 1 553 TRP 553 541 541 TRP TRP A . n 
A 1 554 ALA 554 542 542 ALA ALA A . n 
A 1 555 ILE 555 543 543 ILE ILE A . n 
A 1 556 GLY 556 544 544 GLY GLY A . n 
A 1 557 LEU 557 545 545 LEU LEU A . n 
A 1 558 GLY 558 546 546 GLY GLY A . n 
A 1 559 TRP 559 547 547 TRP TRP A . n 
A 1 560 SER 560 548 548 SER SER A . n 
A 1 561 LEU 561 549 549 LEU LEU A . n 
A 1 562 ALA 562 550 550 ALA ALA A . n 
A 1 563 LEU 563 551 551 LEU LEU A . n 
A 1 564 SER 564 552 552 SER SER A . n 
A 1 565 SER 565 553 553 SER SER A . n 
A 1 566 MET 566 554 554 MET MET A . n 
A 1 567 LEU 567 555 555 LEU LEU A . n 
A 1 568 CYS 568 556 556 CYS CYS A . n 
A 1 569 VAL 569 557 557 VAL VAL A . n 
A 1 570 PRO 570 558 558 PRO PRO A . n 
A 1 571 LEU 571 559 559 LEU LEU A . n 
A 1 572 VAL 572 560 560 VAL VAL A . n 
A 1 573 ILE 573 561 561 ILE ILE A . n 
A 1 574 VAL 574 562 562 VAL VAL A . n 
A 1 575 ILE 575 563 563 ILE ILE A . n 
A 1 576 ARG 576 564 564 ARG ARG A . n 
A 1 577 LEU 577 565 565 LEU LEU A . n 
A 1 578 CYS 578 566 566 CYS CYS A . n 
A 1 579 GLN 579 567 567 GLN GLN A . n 
A 1 580 THR 580 568 568 THR THR A . n 
A 1 581 GLU 581 569 569 GLU GLU A . n 
A 1 582 GLY 582 570 570 GLY GLY A . n 
A 1 583 PRO 583 571 571 PRO PRO A . n 
A 1 584 PHE 584 572 572 PHE PHE A . n 
A 1 585 LEU 585 573 573 LEU LEU A . n 
A 1 586 VAL 586 574 574 VAL VAL A . n 
A 1 587 ARG 587 575 575 ARG ARG A . n 
A 1 588 VAL 588 576 576 VAL VAL A . n 
A 1 589 LYS 589 577 577 LYS LYS A . n 
A 1 590 TYR 590 578 578 TYR TYR A . n 
A 1 591 LEU 591 579 579 LEU LEU A . n 
A 1 592 LEU 592 580 580 LEU LEU A . n 
A 1 593 THR 593 581 581 THR THR A . n 
A 1 594 PRO 594 582 582 PRO PRO A . n 
A 1 595 ARG 595 583 583 ARG ARG A . n 
A 1 596 GLU 596 584 ?   ?   ?   A . n 
A 1 597 PRO 597 585 ?   ?   ?   A . n 
A 1 598 ASN 598 586 ?   ?   ?   A . n 
A 1 599 ARG 599 587 ?   ?   ?   A . n 
A 1 600 TRP 600 588 ?   ?   ?   A . n 
A 1 601 ALA 601 589 ?   ?   ?   A . n 
A 1 602 VAL 602 590 ?   ?   ?   A . n 
A 1 603 GLU 603 591 ?   ?   ?   A . n 
A 1 604 ARG 604 592 ?   ?   ?   A . n 
A 1 605 GLU 605 593 ?   ?   ?   A . n 
A 1 606 GLY 606 594 ?   ?   ?   A . n 
A 1 607 ALA 607 595 ?   ?   ?   A . n 
A 1 608 THR 608 596 ?   ?   ?   A . n 
A 1 609 PRO 609 597 ?   ?   ?   A . n 
A 1 610 TYR 610 598 ?   ?   ?   A . n 
A 1 611 ASN 611 599 ?   ?   ?   A . n 
A 1 612 SER 612 600 ?   ?   ?   A . n 
A 1 613 ARG 613 601 ?   ?   ?   A . n 
A 1 614 THR 614 602 ?   ?   ?   A . n 
A 1 615 VAL 615 603 ?   ?   ?   A . n 
A 1 616 MET 616 604 ?   ?   ?   A . n 
A 1 617 ASN 617 605 ?   ?   ?   A . n 
A 1 618 GLY 618 606 ?   ?   ?   A . n 
A 1 619 ALA 619 607 ?   ?   ?   A . n 
A 1 620 LEU 620 608 ?   ?   ?   A . n 
A 1 621 VAL 621 609 ?   ?   ?   A . n 
A 1 622 LYS 622 610 ?   ?   ?   A . n 
A 1 623 PRO 623 611 ?   ?   ?   A . n 
A 1 624 THR 624 612 ?   ?   ?   A . n 
A 1 625 HIS 625 613 ?   ?   ?   A . n 
A 1 626 ILE 626 614 ?   ?   ?   A . n 
A 1 627 ILE 627 615 ?   ?   ?   A . n 
A 1 628 VAL 628 616 ?   ?   ?   A . n 
A 1 629 GLU 629 617 ?   ?   ?   A . n 
A 1 630 THR 630 618 ?   ?   ?   A . n 
A 1 631 MET 631 619 ?   ?   ?   A . n 
A 1 632 MET 632 620 ?   ?   ?   A . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 TAU ? ? TAU ? ? 'SUBJECT OF INVESTIGATION' ? 
2 CL  ? ? CL  ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 TAU 1 701 601 TAU LIG A . 
C 3 CL  1 702 701 CL  CL  A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A LYS 178 ? CG  ? A LYS 190 CG  
2  1 Y 1 A LYS 178 ? CD  ? A LYS 190 CD  
3  1 Y 1 A LYS 178 ? CE  ? A LYS 190 CE  
4  1 Y 1 A LYS 178 ? NZ  ? A LYS 190 NZ  
5  1 Y 1 A TRP 183 ? CG  ? A TRP 195 CG  
6  1 Y 1 A TRP 183 ? CD1 ? A TRP 195 CD1 
7  1 Y 1 A TRP 183 ? CD2 ? A TRP 195 CD2 
8  1 Y 1 A TRP 183 ? NE1 ? A TRP 195 NE1 
9  1 Y 1 A TRP 183 ? CE2 ? A TRP 195 CE2 
10 1 Y 1 A TRP 183 ? CE3 ? A TRP 195 CE3 
11 1 Y 1 A TRP 183 ? CZ2 ? A TRP 195 CZ2 
12 1 Y 1 A TRP 183 ? CZ3 ? A TRP 195 CZ3 
13 1 Y 1 A TRP 183 ? CH2 ? A TRP 195 CH2 
14 1 Y 1 A ARG 240 ? CG  ? A ARG 252 CG  
15 1 Y 1 A ARG 240 ? CD  ? A ARG 252 CD  
16 1 Y 1 A ARG 240 ? NE  ? A ARG 252 NE  
17 1 Y 1 A ARG 240 ? CZ  ? A ARG 252 CZ  
18 1 Y 1 A ARG 240 ? NH1 ? A ARG 252 NH1 
19 1 Y 1 A ARG 240 ? NH2 ? A ARG 252 NH2 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9K7N 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9K7N 
_struct.title                        
'Cryo-EM structure of human taurine transporter TAUT bound taurine in an occluded state in the saposin-disc' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9K7N 
_struct_keywords.text            'Complex, TRANSPORT PROTEIN' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    SC6A6_HUMAN 
_struct_ref.pdbx_db_accession          P31641 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFL
IPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA
HCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVR
STGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKY
NSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGL
DSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIA
WIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLV
IVIRLCQTEGPFLVRVKYLLTPREPNRWAVEREGATPYNSRTVMNGALVKPTHIIVETMM
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9K7N 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 13 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 632 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             P31641 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  620 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       620 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9K7N MET A 1  ? UNP P31641 ? ? 'initiating methionine' -11 1  
1 9K7N ASP A 2  ? UNP P31641 ? ? 'expression tag'        -10 2  
1 9K7N TYR A 3  ? UNP P31641 ? ? 'expression tag'        -9  3  
1 9K7N LYS A 4  ? UNP P31641 ? ? 'expression tag'        -8  4  
1 9K7N ASP A 5  ? UNP P31641 ? ? 'expression tag'        -7  5  
1 9K7N ASP A 6  ? UNP P31641 ? ? 'expression tag'        -6  6  
1 9K7N ASP A 7  ? UNP P31641 ? ? 'expression tag'        -5  7  
1 9K7N ASP A 8  ? UNP P31641 ? ? 'expression tag'        -4  8  
1 9K7N LYS A 9  ? UNP P31641 ? ? 'expression tag'        -3  9  
1 9K7N GLY A 10 ? UNP P31641 ? ? 'expression tag'        -2  10 
1 9K7N SER A 11 ? UNP P31641 ? ? 'expression tag'        -1  11 
1 9K7N GLY A 12 ? UNP P31641 ? ? 'expression tag'        0   12 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LYS A 59  ? VAL A 71  ? LYS A 47  VAL A 59  1 ? 13 
HELX_P HELX_P2  AA2 GLY A 72  ? TRP A 77  ? GLY A 60  TRP A 65  1 ? 6  
HELX_P HELX_P3  AA3 TRP A 77  ? ASN A 86  ? TRP A 65  ASN A 74  1 ? 10 
HELX_P HELX_P4  AA4 GLY A 88  ? SER A 102 ? GLY A 76  SER A 90  1 ? 15 
HELX_P HELX_P5  AA5 SER A 102 ? SER A 118 ? SER A 90  SER A 106 1 ? 17 
HELX_P HELX_P6  AA6 GLY A 120 ? CYS A 129 ? GLY A 108 CYS A 117 1 ? 10 
HELX_P HELX_P7  AA7 SER A 133 ? PHE A 165 ? SER A 121 PHE A 153 1 ? 33 
HELX_P HELX_P8  AA8 LEU A 169 ? HIS A 173 ? LEU A 157 HIS A 161 5 ? 5  
HELX_P HELX_P9  AA9 GLU A 185 ? ASN A 191 ? GLU A 173 ASN A 179 1 ? 7  
HELX_P HELX_P10 AB1 SER A 205 ? ASN A 214 ? SER A 193 ASN A 202 1 ? 10 
HELX_P HELX_P11 AB2 LYS A 229 ? GLY A 250 ? LYS A 217 GLY A 238 1 ? 22 
HELX_P HELX_P12 AB3 VAL A 251 ? LYS A 256 ? VAL A 239 LYS A 244 1 ? 6  
HELX_P HELX_P13 AB4 VAL A 257 ? LEU A 279 ? VAL A 245 LEU A 267 1 ? 23 
HELX_P HELX_P14 AB5 GLY A 281 ? TYR A 291 ? GLY A 269 TYR A 279 1 ? 11 
HELX_P HELX_P15 AB6 ASP A 293 ? ASP A 299 ? ASP A 281 ASP A 287 1 ? 7  
HELX_P HELX_P16 AB7 ASP A 299 ? TYR A 314 ? ASP A 287 TYR A 302 1 ? 16 
HELX_P HELX_P17 AB8 GLY A 319 ? ASN A 328 ? GLY A 307 ASN A 316 1 ? 10 
HELX_P HELX_P18 AB9 ASN A 333 ? GLY A 368 ? ASN A 321 GLY A 356 1 ? 36 
HELX_P HELX_P19 AC1 ASP A 370 ? VAL A 374 ? ASP A 358 VAL A 362 5 ? 5  
HELX_P HELX_P20 AC2 PRO A 379 ? MET A 393 ? PRO A 367 MET A 381 1 ? 15 
HELX_P HELX_P21 AC3 LEU A 395 ? TYR A 430 ? LEU A 383 TYR A 418 1 ? 36 
HELX_P HELX_P22 AC4 TYR A 430 ? GLY A 437 ? TYR A 418 GLY A 425 1 ? 8  
HELX_P HELX_P23 AC5 TYR A 438 ? LEU A 456 ? TYR A 426 LEU A 444 1 ? 19 
HELX_P HELX_P24 AC6 THR A 457 ? THR A 460 ? THR A 445 THR A 448 5 ? 4  
HELX_P HELX_P25 AC7 GLY A 462 ? ALA A 474 ? GLY A 450 ALA A 462 1 ? 13 
HELX_P HELX_P26 AC8 VAL A 478 ? ILE A 494 ? VAL A 466 ILE A 482 1 ? 17 
HELX_P HELX_P27 AC9 GLY A 496 ? GLY A 509 ? GLY A 484 GLY A 497 1 ? 14 
HELX_P HELX_P28 AD1 PRO A 514 ? VAL A 522 ? PRO A 502 VAL A 510 1 ? 9  
HELX_P HELX_P29 AD2 VAL A 522 ? LYS A 538 ? VAL A 510 LYS A 526 1 ? 17 
HELX_P HELX_P30 AD3 PRO A 551 ? THR A 580 ? PRO A 539 THR A 568 1 ? 30 
HELX_P HELX_P31 AD4 PRO A 583 ? THR A 593 ? PRO A 571 THR A 581 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            disulf1 
_struct_conn.conn_type_id                  disulf 
_struct_conn.pdbx_leaving_atom_flag        ? 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           A 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            174 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           A 
_struct_conn.ptnr2_label_comp_id           CYS 
_struct_conn.ptnr2_label_seq_id            183 
_struct_conn.ptnr2_label_atom_id           SG 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            A 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             162 
_struct_conn.ptnr2_auth_asym_id            A 
_struct_conn.ptnr2_auth_comp_id            CYS 
_struct_conn.ptnr2_auth_seq_id             171 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               2.047 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      CYS 
_pdbx_modification_feature.label_asym_id                      A 
_pdbx_modification_feature.label_seq_id                       174 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     A 
_pdbx_modification_feature.modified_residue_label_seq_id      183 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       CYS 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        162 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      A 
_pdbx_modification_feature.modified_residue_auth_seq_id       171 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               SG 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                . 
_pdbx_modification_feature.ref_pcm_id                         . 
_pdbx_modification_feature.ref_comp_id                        . 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Disulfide bridge' 
# 
_struct_sheet.id               AA1 
_struct_sheet.type             ? 
_struct_sheet.number_strands   2 
_struct_sheet.details          ? 
# 
_struct_sheet_order.sheet_id     AA1 
_struct_sheet_order.range_id_1   1 
_struct_sheet_order.range_id_2   2 
_struct_sheet_order.offset       ? 
_struct_sheet_order.sense        anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 THR A 543 ? TYR A 544 ? THR A 531 TYR A 532 
AA1 2 TYR A 548 ? VAL A 549 ? TYR A 536 VAL A 537 
# 
_pdbx_struct_sheet_hbond.sheet_id                AA1 
_pdbx_struct_sheet_hbond.range_id_1              1 
_pdbx_struct_sheet_hbond.range_id_2              2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id   O 
_pdbx_struct_sheet_hbond.range_1_label_comp_id   TYR 
_pdbx_struct_sheet_hbond.range_1_label_asym_id   A 
_pdbx_struct_sheet_hbond.range_1_label_seq_id    544 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id    O 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id    TYR 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id    A 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id     532 
_pdbx_struct_sheet_hbond.range_2_label_atom_id   N 
_pdbx_struct_sheet_hbond.range_2_label_comp_id   TYR 
_pdbx_struct_sheet_hbond.range_2_label_asym_id   A 
_pdbx_struct_sheet_hbond.range_2_label_seq_id    548 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id    N 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id    TYR 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id    A 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id     536 
# 
_pdbx_entry_details.entry_id                   9K7N 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   OH 
_pdbx_validate_close_contact.auth_asym_id_1   A 
_pdbx_validate_close_contact.auth_comp_id_1   TYR 
_pdbx_validate_close_contact.auth_seq_id_1    83 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   CL 
_pdbx_validate_close_contact.auth_asym_id_2   A 
_pdbx_validate_close_contact.auth_comp_id_2   CL 
_pdbx_validate_close_contact.auth_seq_id_2    702 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.12 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 SER A 46  ? ? 54.85  -129.98 
2 1 ALA A 463 ? ? 59.57  17.78   
3 1 PRO A 502 ? ? -52.79 -9.59   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9K7N 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9K7N 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.3 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               99965 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Sodium- and chloride-dependent taurine transporter' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9K7N 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            50 
_em_imaging.illumination_mode               'SPOT SCAN' 
_em_imaging.mode                            DIFFRACTION 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             3000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9K7N 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9K7N 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET -11 ? A MET 1   
2  1 Y 1 A ASP -10 ? A ASP 2   
3  1 Y 1 A TYR -9  ? A TYR 3   
4  1 Y 1 A LYS -8  ? A LYS 4   
5  1 Y 1 A ASP -7  ? A ASP 5   
6  1 Y 1 A ASP -6  ? A ASP 6   
7  1 Y 1 A ASP -5  ? A ASP 7   
8  1 Y 1 A ASP -4  ? A ASP 8   
9  1 Y 1 A LYS -3  ? A LYS 9   
10 1 Y 1 A GLY -2  ? A GLY 10  
11 1 Y 1 A SER -1  ? A SER 11  
12 1 Y 1 A GLY 0   ? A GLY 12  
13 1 Y 1 A MET 1   ? A MET 13  
14 1 Y 1 A ALA 2   ? A ALA 14  
15 1 Y 1 A THR 3   ? A THR 15  
16 1 Y 1 A LYS 4   ? A LYS 16  
17 1 Y 1 A GLU 5   ? A GLU 17  
18 1 Y 1 A LYS 6   ? A LYS 18  
19 1 Y 1 A LEU 7   ? A LEU 19  
20 1 Y 1 A GLN 8   ? A GLN 20  
21 1 Y 1 A CYS 9   ? A CYS 21  
22 1 Y 1 A LEU 10  ? A LEU 22  
23 1 Y 1 A LYS 11  ? A LYS 23  
24 1 Y 1 A ASP 12  ? A ASP 24  
25 1 Y 1 A PHE 13  ? A PHE 25  
26 1 Y 1 A HIS 14  ? A HIS 26  
27 1 Y 1 A LYS 15  ? A LYS 27  
28 1 Y 1 A ASP 16  ? A ASP 28  
29 1 Y 1 A ILE 17  ? A ILE 29  
30 1 Y 1 A LEU 18  ? A LEU 30  
31 1 Y 1 A LYS 19  ? A LYS 31  
32 1 Y 1 A PRO 20  ? A PRO 32  
33 1 Y 1 A SER 21  ? A SER 33  
34 1 Y 1 A PRO 22  ? A PRO 34  
35 1 Y 1 A GLY 23  ? A GLY 35  
36 1 Y 1 A LYS 24  ? A LYS 36  
37 1 Y 1 A SER 25  ? A SER 37  
38 1 Y 1 A PRO 26  ? A PRO 38  
39 1 Y 1 A GLY 27  ? A GLY 39  
40 1 Y 1 A THR 28  ? A THR 40  
41 1 Y 1 A ARG 29  ? A ARG 41  
42 1 Y 1 A PRO 30  ? A PRO 42  
43 1 Y 1 A GLU 31  ? A GLU 43  
44 1 Y 1 A ASP 32  ? A ASP 44  
45 1 Y 1 A GLU 33  ? A GLU 45  
46 1 Y 1 A ALA 34  ? A ALA 46  
47 1 Y 1 A GLU 35  ? A GLU 47  
48 1 Y 1 A GLY 36  ? A GLY 48  
49 1 Y 1 A LYS 37  ? A LYS 49  
50 1 Y 1 A PRO 38  ? A PRO 50  
51 1 Y 1 A GLU 584 ? A GLU 596 
52 1 Y 1 A PRO 585 ? A PRO 597 
53 1 Y 1 A ASN 586 ? A ASN 598 
54 1 Y 1 A ARG 587 ? A ARG 599 
55 1 Y 1 A TRP 588 ? A TRP 600 
56 1 Y 1 A ALA 589 ? A ALA 601 
57 1 Y 1 A VAL 590 ? A VAL 602 
58 1 Y 1 A GLU 591 ? A GLU 603 
59 1 Y 1 A ARG 592 ? A ARG 604 
60 1 Y 1 A GLU 593 ? A GLU 605 
61 1 Y 1 A GLY 594 ? A GLY 606 
62 1 Y 1 A ALA 595 ? A ALA 607 
63 1 Y 1 A THR 596 ? A THR 608 
64 1 Y 1 A PRO 597 ? A PRO 609 
65 1 Y 1 A TYR 598 ? A TYR 610 
66 1 Y 1 A ASN 599 ? A ASN 611 
67 1 Y 1 A SER 600 ? A SER 612 
68 1 Y 1 A ARG 601 ? A ARG 613 
69 1 Y 1 A THR 602 ? A THR 614 
70 1 Y 1 A VAL 603 ? A VAL 615 
71 1 Y 1 A MET 604 ? A MET 616 
72 1 Y 1 A ASN 605 ? A ASN 617 
73 1 Y 1 A GLY 606 ? A GLY 618 
74 1 Y 1 A ALA 607 ? A ALA 619 
75 1 Y 1 A LEU 608 ? A LEU 620 
76 1 Y 1 A VAL 609 ? A VAL 621 
77 1 Y 1 A LYS 610 ? A LYS 622 
78 1 Y 1 A PRO 611 ? A PRO 623 
79 1 Y 1 A THR 612 ? A THR 624 
80 1 Y 1 A HIS 613 ? A HIS 625 
81 1 Y 1 A ILE 614 ? A ILE 626 
82 1 Y 1 A ILE 615 ? A ILE 627 
83 1 Y 1 A VAL 616 ? A VAL 628 
84 1 Y 1 A GLU 617 ? A GLU 629 
85 1 Y 1 A THR 618 ? A THR 630 
86 1 Y 1 A MET 619 ? A MET 631 
87 1 Y 1 A MET 620 ? A MET 632 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CL  CL   CL N N 74  
CYS N    N  N N 75  
CYS CA   C  N R 76  
CYS C    C  N N 77  
CYS O    O  N N 78  
CYS CB   C  N N 79  
CYS SG   S  N N 80  
CYS OXT  O  N N 81  
CYS H    H  N N 82  
CYS H2   H  N N 83  
CYS HA   H  N N 84  
CYS HB2  H  N N 85  
CYS HB3  H  N N 86  
CYS HG   H  N N 87  
CYS HXT  H  N N 88  
GLN N    N  N N 89  
GLN CA   C  N S 90  
GLN C    C  N N 91  
GLN O    O  N N 92  
GLN CB   C  N N 93  
GLN CG   C  N N 94  
GLN CD   C  N N 95  
GLN OE1  O  N N 96  
GLN NE2  N  N N 97  
GLN OXT  O  N N 98  
GLN H    H  N N 99  
GLN H2   H  N N 100 
GLN HA   H  N N 101 
GLN HB2  H  N N 102 
GLN HB3  H  N N 103 
GLN HG2  H  N N 104 
GLN HG3  H  N N 105 
GLN HE21 H  N N 106 
GLN HE22 H  N N 107 
GLN HXT  H  N N 108 
GLU N    N  N N 109 
GLU CA   C  N S 110 
GLU C    C  N N 111 
GLU O    O  N N 112 
GLU CB   C  N N 113 
GLU CG   C  N N 114 
GLU CD   C  N N 115 
GLU OE1  O  N N 116 
GLU OE2  O  N N 117 
GLU OXT  O  N N 118 
GLU H    H  N N 119 
GLU H2   H  N N 120 
GLU HA   H  N N 121 
GLU HB2  H  N N 122 
GLU HB3  H  N N 123 
GLU HG2  H  N N 124 
GLU HG3  H  N N 125 
GLU HE2  H  N N 126 
GLU HXT  H  N N 127 
GLY N    N  N N 128 
GLY CA   C  N N 129 
GLY C    C  N N 130 
GLY O    O  N N 131 
GLY OXT  O  N N 132 
GLY H    H  N N 133 
GLY H2   H  N N 134 
GLY HA2  H  N N 135 
GLY HA3  H  N N 136 
GLY HXT  H  N N 137 
HIS N    N  N N 138 
HIS CA   C  N S 139 
HIS C    C  N N 140 
HIS O    O  N N 141 
HIS CB   C  N N 142 
HIS CG   C  Y N 143 
HIS ND1  N  Y N 144 
HIS CD2  C  Y N 145 
HIS CE1  C  Y N 146 
HIS NE2  N  Y N 147 
HIS OXT  O  N N 148 
HIS H    H  N N 149 
HIS H2   H  N N 150 
HIS HA   H  N N 151 
HIS HB2  H  N N 152 
HIS HB3  H  N N 153 
HIS HD1  H  N N 154 
HIS HD2  H  N N 155 
HIS HE1  H  N N 156 
HIS HE2  H  N N 157 
HIS HXT  H  N N 158 
ILE N    N  N N 159 
ILE CA   C  N S 160 
ILE C    C  N N 161 
ILE O    O  N N 162 
ILE CB   C  N S 163 
ILE CG1  C  N N 164 
ILE CG2  C  N N 165 
ILE CD1  C  N N 166 
ILE OXT  O  N N 167 
ILE H    H  N N 168 
ILE H2   H  N N 169 
ILE HA   H  N N 170 
ILE HB   H  N N 171 
ILE HG12 H  N N 172 
ILE HG13 H  N N 173 
ILE HG21 H  N N 174 
ILE HG22 H  N N 175 
ILE HG23 H  N N 176 
ILE HD11 H  N N 177 
ILE HD12 H  N N 178 
ILE HD13 H  N N 179 
ILE HXT  H  N N 180 
LEU N    N  N N 181 
LEU CA   C  N S 182 
LEU C    C  N N 183 
LEU O    O  N N 184 
LEU CB   C  N N 185 
LEU CG   C  N N 186 
LEU CD1  C  N N 187 
LEU CD2  C  N N 188 
LEU OXT  O  N N 189 
LEU H    H  N N 190 
LEU H2   H  N N 191 
LEU HA   H  N N 192 
LEU HB2  H  N N 193 
LEU HB3  H  N N 194 
LEU HG   H  N N 195 
LEU HD11 H  N N 196 
LEU HD12 H  N N 197 
LEU HD13 H  N N 198 
LEU HD21 H  N N 199 
LEU HD22 H  N N 200 
LEU HD23 H  N N 201 
LEU HXT  H  N N 202 
LYS N    N  N N 203 
LYS CA   C  N S 204 
LYS C    C  N N 205 
LYS O    O  N N 206 
LYS CB   C  N N 207 
LYS CG   C  N N 208 
LYS CD   C  N N 209 
LYS CE   C  N N 210 
LYS NZ   N  N N 211 
LYS OXT  O  N N 212 
LYS H    H  N N 213 
LYS H2   H  N N 214 
LYS HA   H  N N 215 
LYS HB2  H  N N 216 
LYS HB3  H  N N 217 
LYS HG2  H  N N 218 
LYS HG3  H  N N 219 
LYS HD2  H  N N 220 
LYS HD3  H  N N 221 
LYS HE2  H  N N 222 
LYS HE3  H  N N 223 
LYS HZ1  H  N N 224 
LYS HZ2  H  N N 225 
LYS HZ3  H  N N 226 
LYS HXT  H  N N 227 
MET N    N  N N 228 
MET CA   C  N S 229 
MET C    C  N N 230 
MET O    O  N N 231 
MET CB   C  N N 232 
MET CG   C  N N 233 
MET SD   S  N N 234 
MET CE   C  N N 235 
MET OXT  O  N N 236 
MET H    H  N N 237 
MET H2   H  N N 238 
MET HA   H  N N 239 
MET HB2  H  N N 240 
MET HB3  H  N N 241 
MET HG2  H  N N 242 
MET HG3  H  N N 243 
MET HE1  H  N N 244 
MET HE2  H  N N 245 
MET HE3  H  N N 246 
MET HXT  H  N N 247 
PHE N    N  N N 248 
PHE CA   C  N S 249 
PHE C    C  N N 250 
PHE O    O  N N 251 
PHE CB   C  N N 252 
PHE CG   C  Y N 253 
PHE CD1  C  Y N 254 
PHE CD2  C  Y N 255 
PHE CE1  C  Y N 256 
PHE CE2  C  Y N 257 
PHE CZ   C  Y N 258 
PHE OXT  O  N N 259 
PHE H    H  N N 260 
PHE H2   H  N N 261 
PHE HA   H  N N 262 
PHE HB2  H  N N 263 
PHE HB3  H  N N 264 
PHE HD1  H  N N 265 
PHE HD2  H  N N 266 
PHE HE1  H  N N 267 
PHE HE2  H  N N 268 
PHE HZ   H  N N 269 
PHE HXT  H  N N 270 
PRO N    N  N N 271 
PRO CA   C  N S 272 
PRO C    C  N N 273 
PRO O    O  N N 274 
PRO CB   C  N N 275 
PRO CG   C  N N 276 
PRO CD   C  N N 277 
PRO OXT  O  N N 278 
PRO H    H  N N 279 
PRO HA   H  N N 280 
PRO HB2  H  N N 281 
PRO HB3  H  N N 282 
PRO HG2  H  N N 283 
PRO HG3  H  N N 284 
PRO HD2  H  N N 285 
PRO HD3  H  N N 286 
PRO HXT  H  N N 287 
SER N    N  N N 288 
SER CA   C  N S 289 
SER C    C  N N 290 
SER O    O  N N 291 
SER CB   C  N N 292 
SER OG   O  N N 293 
SER OXT  O  N N 294 
SER H    H  N N 295 
SER H2   H  N N 296 
SER HA   H  N N 297 
SER HB2  H  N N 298 
SER HB3  H  N N 299 
SER HG   H  N N 300 
SER HXT  H  N N 301 
TAU C1   C  N N 302 
TAU C2   C  N N 303 
TAU N1   N  N N 304 
TAU S    S  N N 305 
TAU O1   O  N N 306 
TAU O2   O  N N 307 
TAU O3   O  N N 308 
TAU H1C1 H  N N 309 
TAU H1C2 H  N N 310 
TAU H2C1 H  N N 311 
TAU H2C2 H  N N 312 
TAU H1N1 H  N N 313 
TAU H1N2 H  N N 314 
TAU H2   H  N N 315 
THR N    N  N N 316 
THR CA   C  N S 317 
THR C    C  N N 318 
THR O    O  N N 319 
THR CB   C  N R 320 
THR OG1  O  N N 321 
THR CG2  C  N N 322 
THR OXT  O  N N 323 
THR H    H  N N 324 
THR H2   H  N N 325 
THR HA   H  N N 326 
THR HB   H  N N 327 
THR HG1  H  N N 328 
THR HG21 H  N N 329 
THR HG22 H  N N 330 
THR HG23 H  N N 331 
THR HXT  H  N N 332 
TRP N    N  N N 333 
TRP CA   C  N S 334 
TRP C    C  N N 335 
TRP O    O  N N 336 
TRP CB   C  N N 337 
TRP CG   C  Y N 338 
TRP CD1  C  Y N 339 
TRP CD2  C  Y N 340 
TRP NE1  N  Y N 341 
TRP CE2  C  Y N 342 
TRP CE3  C  Y N 343 
TRP CZ2  C  Y N 344 
TRP CZ3  C  Y N 345 
TRP CH2  C  Y N 346 
TRP OXT  O  N N 347 
TRP H    H  N N 348 
TRP H2   H  N N 349 
TRP HA   H  N N 350 
TRP HB2  H  N N 351 
TRP HB3  H  N N 352 
TRP HD1  H  N N 353 
TRP HE1  H  N N 354 
TRP HE3  H  N N 355 
TRP HZ2  H  N N 356 
TRP HZ3  H  N N 357 
TRP HH2  H  N N 358 
TRP HXT  H  N N 359 
TYR N    N  N N 360 
TYR CA   C  N S 361 
TYR C    C  N N 362 
TYR O    O  N N 363 
TYR CB   C  N N 364 
TYR CG   C  Y N 365 
TYR CD1  C  Y N 366 
TYR CD2  C  Y N 367 
TYR CE1  C  Y N 368 
TYR CE2  C  Y N 369 
TYR CZ   C  Y N 370 
TYR OH   O  N N 371 
TYR OXT  O  N N 372 
TYR H    H  N N 373 
TYR H2   H  N N 374 
TYR HA   H  N N 375 
TYR HB2  H  N N 376 
TYR HB3  H  N N 377 
TYR HD1  H  N N 378 
TYR HD2  H  N N 379 
TYR HE1  H  N N 380 
TYR HE2  H  N N 381 
TYR HH   H  N N 382 
TYR HXT  H  N N 383 
VAL N    N  N N 384 
VAL CA   C  N S 385 
VAL C    C  N N 386 
VAL O    O  N N 387 
VAL CB   C  N N 388 
VAL CG1  C  N N 389 
VAL CG2  C  N N 390 
VAL OXT  O  N N 391 
VAL H    H  N N 392 
VAL H2   H  N N 393 
VAL HA   H  N N 394 
VAL HB   H  N N 395 
VAL HG11 H  N N 396 
VAL HG12 H  N N 397 
VAL HG13 H  N N 398 
VAL HG21 H  N N 399 
VAL HG22 H  N N 400 
VAL HG23 H  N N 401 
VAL HXT  H  N N 402 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
TAU C1  C2   sing N N 288 
TAU C1  N1   sing N N 289 
TAU C1  H1C1 sing N N 290 
TAU C1  H1C2 sing N N 291 
TAU C2  S    sing N N 292 
TAU C2  H2C1 sing N N 293 
TAU C2  H2C2 sing N N 294 
TAU N1  H1N1 sing N N 295 
TAU N1  H1N2 sing N N 296 
TAU S   O1   doub N N 297 
TAU S   O2   sing N N 298 
TAU S   O3   doub N N 299 
TAU O2  H2   sing N N 300 
THR N   CA   sing N N 301 
THR N   H    sing N N 302 
THR N   H2   sing N N 303 
THR CA  C    sing N N 304 
THR CA  CB   sing N N 305 
THR CA  HA   sing N N 306 
THR C   O    doub N N 307 
THR C   OXT  sing N N 308 
THR CB  OG1  sing N N 309 
THR CB  CG2  sing N N 310 
THR CB  HB   sing N N 311 
THR OG1 HG1  sing N N 312 
THR CG2 HG21 sing N N 313 
THR CG2 HG22 sing N N 314 
THR CG2 HG23 sing N N 315 
THR OXT HXT  sing N N 316 
TRP N   CA   sing N N 317 
TRP N   H    sing N N 318 
TRP N   H2   sing N N 319 
TRP CA  C    sing N N 320 
TRP CA  CB   sing N N 321 
TRP CA  HA   sing N N 322 
TRP C   O    doub N N 323 
TRP C   OXT  sing N N 324 
TRP CB  CG   sing N N 325 
TRP CB  HB2  sing N N 326 
TRP CB  HB3  sing N N 327 
TRP CG  CD1  doub Y N 328 
TRP CG  CD2  sing Y N 329 
TRP CD1 NE1  sing Y N 330 
TRP CD1 HD1  sing N N 331 
TRP CD2 CE2  doub Y N 332 
TRP CD2 CE3  sing Y N 333 
TRP NE1 CE2  sing Y N 334 
TRP NE1 HE1  sing N N 335 
TRP CE2 CZ2  sing Y N 336 
TRP CE3 CZ3  doub Y N 337 
TRP CE3 HE3  sing N N 338 
TRP CZ2 CH2  doub Y N 339 
TRP CZ2 HZ2  sing N N 340 
TRP CZ3 CH2  sing Y N 341 
TRP CZ3 HZ3  sing N N 342 
TRP CH2 HH2  sing N N 343 
TRP OXT HXT  sing N N 344 
TYR N   CA   sing N N 345 
TYR N   H    sing N N 346 
TYR N   H2   sing N N 347 
TYR CA  C    sing N N 348 
TYR CA  CB   sing N N 349 
TYR CA  HA   sing N N 350 
TYR C   O    doub N N 351 
TYR C   OXT  sing N N 352 
TYR CB  CG   sing N N 353 
TYR CB  HB2  sing N N 354 
TYR CB  HB3  sing N N 355 
TYR CG  CD1  doub Y N 356 
TYR CG  CD2  sing Y N 357 
TYR CD1 CE1  sing Y N 358 
TYR CD1 HD1  sing N N 359 
TYR CD2 CE2  doub Y N 360 
TYR CD2 HD2  sing N N 361 
TYR CE1 CZ   doub Y N 362 
TYR CE1 HE1  sing N N 363 
TYR CE2 CZ   sing Y N 364 
TYR CE2 HE2  sing N N 365 
TYR CZ  OH   sing N N 366 
TYR OH  HH   sing N N 367 
TYR OXT HXT  sing N N 368 
VAL N   CA   sing N N 369 
VAL N   H    sing N N 370 
VAL N   H2   sing N N 371 
VAL CA  C    sing N N 372 
VAL CA  CB   sing N N 373 
VAL CA  HA   sing N N 374 
VAL C   O    doub N N 375 
VAL C   OXT  sing N N 376 
VAL CB  CG1  sing N N 377 
VAL CB  CG2  sing N N 378 
VAL CB  HB   sing N N 379 
VAL CG1 HG11 sing N N 380 
VAL CG1 HG12 sing N N 381 
VAL CG1 HG13 sing N N 382 
VAL CG2 HG21 sing N N 383 
VAL CG2 HG22 sing N N 384 
VAL CG2 HG23 sing N N 385 
VAL OXT HXT  sing N N 386 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-10-24 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9K7N 
_em_admin.last_update        2025-02-26 
_em_admin.map_release_date   2025-02-26 
_em_admin.title              
'Cryo-EM structure of human taurine transporter TAUT bound taurine in an occluded state in the saposin-disc' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9K7N 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CL 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . PRO A 1 51  ? 132.974 102.398 115.691 1.00 62.69 ? 39  PRO A N   1 
ATOM   2    C  CA  . PRO A 1 51  ? 133.984 101.829 114.793 1.00 62.69 ? 39  PRO A CA  1 
ATOM   3    C  C   . PRO A 1 51  ? 133.952 102.490 113.426 1.00 62.69 ? 39  PRO A C   1 
ATOM   4    O  O   . PRO A 1 51  ? 133.541 103.645 113.314 1.00 62.69 ? 39  PRO A O   1 
ATOM   5    C  CB  . PRO A 1 51  ? 133.549 100.370 114.671 1.00 62.69 ? 39  PRO A CB  1 
ATOM   6    C  CG  . PRO A 1 51  ? 132.071 100.412 114.852 1.00 62.69 ? 39  PRO A CG  1 
ATOM   7    C  CD  . PRO A 1 51  ? 131.804 101.515 115.840 1.00 62.69 ? 39  PRO A CD  1 
ATOM   8    N  N   . GLN A 1 52  ? 134.383 101.770 112.397 1.00 70.48 ? 40  GLN A N   1 
ATOM   9    C  CA  . GLN A 1 52  ? 134.359 102.310 111.045 1.00 70.48 ? 40  GLN A CA  1 
ATOM   10   C  C   . GLN A 1 52  ? 132.925 102.538 110.595 1.00 70.48 ? 40  GLN A C   1 
ATOM   11   O  O   . GLN A 1 52  ? 132.044 101.724 110.876 1.00 70.48 ? 40  GLN A O   1 
ATOM   12   C  CB  . GLN A 1 52  ? 135.079 101.356 110.084 1.00 70.48 ? 40  GLN A CB  1 
ATOM   13   C  CG  . GLN A 1 52  ? 135.364 101.924 108.699 1.00 70.48 ? 40  GLN A CG  1 
ATOM   14   C  CD  . GLN A 1 52  ? 134.306 101.558 107.672 1.00 70.48 ? 40  GLN A CD  1 
ATOM   15   O  OE1 . GLN A 1 52  ? 133.474 100.682 107.903 1.00 70.48 ? 40  GLN A OE1 1 
ATOM   16   N  NE2 . GLN A 1 52  ? 134.339 102.230 106.527 1.00 70.48 ? 40  GLN A NE2 1 
ATOM   17   N  N   . ARG A 1 53  ? 132.683 103.636 109.890 1.00 82.07 ? 41  ARG A N   1 
ATOM   18   C  CA  . ARG A 1 53  ? 131.351 103.896 109.367 1.00 82.07 ? 41  ARG A CA  1 
ATOM   19   C  C   . ARG A 1 53  ? 131.436 103.876 107.853 1.00 82.07 ? 41  ARG A C   1 
ATOM   20   O  O   . ARG A 1 53  ? 132.327 104.493 107.273 1.00 82.07 ? 41  ARG A O   1 
ATOM   21   C  CB  . ARG A 1 53  ? 130.822 105.241 109.865 1.00 82.07 ? 41  ARG A CB  1 
ATOM   22   C  CG  . ARG A 1 53  ? 129.309 105.369 109.806 1.00 82.07 ? 41  ARG A CG  1 
ATOM   23   C  CD  . ARG A 1 53  ? 128.645 104.209 110.533 1.00 82.07 ? 41  ARG A CD  1 
ATOM   24   N  NE  . ARG A 1 53  ? 127.189 104.318 110.549 1.00 82.07 ? 41  ARG A NE  1 
ATOM   25   C  CZ  . ARG A 1 53  ? 126.482 104.776 111.577 1.00 82.07 ? 41  ARG A CZ  1 
ATOM   26   N  NH1 . ARG A 1 53  ? 127.095 105.168 112.686 1.00 82.07 ? 41  ARG A NH1 1 
ATOM   27   N  NH2 . ARG A 1 53  ? 125.160 104.838 111.498 1.00 82.07 ? 41  ARG A NH2 1 
ATOM   28   N  N   . GLU A 1 54  ? 130.536 103.139 107.210 1.00 85.96 ? 42  GLU A N   1 
ATOM   29   C  CA  . GLU A 1 54  ? 130.541 103.038 105.753 1.00 85.96 ? 42  GLU A CA  1 
ATOM   30   C  C   . GLU A 1 54  ? 130.312 104.400 105.131 1.00 85.96 ? 42  GLU A C   1 
ATOM   31   O  O   . GLU A 1 54  ? 129.472 105.158 105.597 1.00 85.96 ? 42  GLU A O   1 
ATOM   32   C  CB  . GLU A 1 54  ? 129.456 102.061 105.286 1.00 85.96 ? 42  GLU A CB  1 
ATOM   33   C  CG  . GLU A 1 54  ? 129.443 101.776 103.789 1.00 85.96 ? 42  GLU A CG  1 
ATOM   34   C  CD  . GLU A 1 54  ? 128.409 102.593 103.033 1.00 85.96 ? 42  GLU A CD  1 
ATOM   35   O  OE1 . GLU A 1 54  ? 127.487 103.138 103.674 1.00 85.96 ? 42  GLU A OE1 1 
ATOM   36   O  OE2 . GLU A 1 54  ? 128.514 102.685 101.792 1.00 85.96 ? 42  GLU A OE2 1 
ATOM   37   N  N   . LYS A 1 55  ? 131.056 104.721 104.081 1.00 90.82 ? 43  LYS A N   1 
ATOM   38   C  CA  . LYS A 1 55  ? 130.841 105.982 103.389 1.00 90.82 ? 43  LYS A CA  1 
ATOM   39   C  C   . LYS A 1 55  ? 130.366 105.697 101.978 1.00 90.82 ? 43  LYS A C   1 
ATOM   40   O  O   . LYS A 1 55  ? 130.957 104.881 101.275 1.00 90.82 ? 43  LYS A O   1 
ATOM   41   C  CB  . LYS A 1 55  ? 132.119 106.820 103.364 1.00 90.82 ? 43  LYS A CB  1 
ATOM   42   C  CG  . LYS A 1 55  ? 132.081 108.046 104.267 1.00 90.82 ? 43  LYS A CG  1 
ATOM   43   C  CD  . LYS A 1 55  ? 131.877 107.667 105.726 1.00 90.82 ? 43  LYS A CD  1 
ATOM   44   C  CE  . LYS A 1 55  ? 131.549 108.880 106.581 1.00 90.82 ? 43  LYS A CE  1 
ATOM   45   N  NZ  . LYS A 1 55  ? 131.124 108.490 107.954 1.00 90.82 ? 43  LYS A NZ  1 
ATOM   46   N  N   . TRP A 1 56  ? 129.293 106.360 101.563 1.00 93.10 ? 44  TRP A N   1 
ATOM   47   C  CA  . TRP A 1 56  ? 128.763 106.137 100.228 1.00 93.10 ? 44  TRP A CA  1 
ATOM   48   C  C   . TRP A 1 56  ? 129.810 106.536 99.205  1.00 93.10 ? 44  TRP A C   1 
ATOM   49   O  O   . TRP A 1 56  ? 130.445 107.583 99.332  1.00 93.10 ? 44  TRP A O   1 
ATOM   50   C  CB  . TRP A 1 56  ? 127.508 106.974 99.987  1.00 93.10 ? 44  TRP A CB  1 
ATOM   51   C  CG  . TRP A 1 56  ? 126.342 106.672 100.873 1.00 93.10 ? 44  TRP A CG  1 
ATOM   52   C  CD1 . TRP A 1 56  ? 125.759 107.517 101.766 1.00 93.10 ? 44  TRP A CD1 1 
ATOM   53   C  CD2 . TRP A 1 56  ? 125.599 105.449 100.935 1.00 93.10 ? 44  TRP A CD2 1 
ATOM   54   N  NE1 . TRP A 1 56  ? 124.700 106.900 102.382 1.00 93.10 ? 44  TRP A NE1 1 
ATOM   55   C  CE2 . TRP A 1 56  ? 124.584 105.626 101.893 1.00 93.10 ? 44  TRP A CE2 1 
ATOM   56   C  CE3 . TRP A 1 56  ? 125.697 104.220 100.278 1.00 93.10 ? 44  TRP A CE3 1 
ATOM   57   C  CZ2 . TRP A 1 56  ? 123.676 104.622 102.211 1.00 93.10 ? 44  TRP A CZ2 1 
ATOM   58   C  CZ3 . TRP A 1 56  ? 124.795 103.225 100.595 1.00 93.10 ? 44  TRP A CZ3 1 
ATOM   59   C  CH2 . TRP A 1 56  ? 123.797 103.431 101.553 1.00 93.10 ? 44  TRP A CH2 1 
ATOM   60   N  N   . SER A 1 57  ? 129.984 105.712 98.179  1.00 89.44 ? 45  SER A N   1 
ATOM   61   C  CA  . SER A 1 57  ? 130.966 106.014 97.150  1.00 89.44 ? 45  SER A CA  1 
ATOM   62   C  C   . SER A 1 57  ? 130.551 107.226 96.337  1.00 89.44 ? 45  SER A C   1 
ATOM   63   O  O   . SER A 1 57  ? 129.372 107.375 96.014  1.00 89.44 ? 45  SER A O   1 
ATOM   64   C  CB  . SER A 1 57  ? 131.158 104.811 96.230  1.00 89.44 ? 45  SER A CB  1 
ATOM   65   O  OG  . SER A 1 57  ? 132.075 105.107 95.192  1.00 89.44 ? 45  SER A OG  1 
ATOM   66   N  N   . SER A 1 58  ? 131.504 108.101 96.025  1.00 92.16 ? 46  SER A N   1 
ATOM   67   C  CA  . SER A 1 58  ? 131.216 109.271 95.192  1.00 92.16 ? 46  SER A CA  1 
ATOM   68   C  C   . SER A 1 58  ? 130.076 110.098 95.764  1.00 92.16 ? 46  SER A C   1 
ATOM   69   O  O   . SER A 1 58  ? 130.081 110.441 96.947  1.00 92.16 ? 46  SER A O   1 
ATOM   70   C  CB  . SER A 1 58  ? 130.929 108.866 93.739  1.00 92.16 ? 46  SER A CB  1 
ATOM   71   O  OG  . SER A 1 58  ? 130.947 109.991 92.876  1.00 92.16 ? 46  SER A OG  1 
ATOM   72   N  N   . LYS A 1 59  ? 129.099 110.423 94.928  1.00 93.59 ? 47  LYS A N   1 
ATOM   73   C  CA  . LYS A 1 59  ? 127.952 111.191 95.386  1.00 93.59 ? 47  LYS A CA  1 
ATOM   74   C  C   . LYS A 1 59  ? 126.676 110.458 95.017  1.00 93.59 ? 47  LYS A C   1 
ATOM   75   O  O   . LYS A 1 59  ? 125.698 110.497 95.760  1.00 93.59 ? 47  LYS A O   1 
ATOM   76   C  CB  . LYS A 1 59  ? 127.968 112.589 94.771  1.00 93.59 ? 47  LYS A CB  1 
ATOM   77   C  CG  . LYS A 1 59  ? 128.318 112.633 93.293  1.00 93.59 ? 47  LYS A CG  1 
ATOM   78   C  CD  . LYS A 1 59  ? 128.230 114.052 92.759  1.00 93.59 ? 47  LYS A CD  1 
ATOM   79   C  CE  . LYS A 1 59  ? 129.123 114.995 93.548  1.00 93.59 ? 47  LYS A CE  1 
ATOM   80   N  NZ  . LYS A 1 59  ? 130.563 114.629 93.434  1.00 93.59 ? 47  LYS A NZ  1 
ATOM   81   N  N   . ILE A 1 60  ? 126.686 109.783 93.872  1.00 94.88 ? 48  ILE A N   1 
ATOM   82   C  CA  . ILE A 1 60  ? 125.518 109.011 93.447  1.00 94.88 ? 48  ILE A CA  1 
ATOM   83   C  C   . ILE A 1 60  ? 125.027 107.921 94.412  1.00 94.88 ? 48  ILE A C   1 
ATOM   84   O  O   . ILE A 1 60  ? 123.824 107.743 94.568  1.00 94.88 ? 48  ILE A O   1 
ATOM   85   C  CB  . ILE A 1 60  ? 125.697 108.489 91.993  1.00 94.88 ? 48  ILE A CB  1 
ATOM   86   C  CG1 . ILE A 1 60  ? 124.362 108.505 91.246  1.00 94.88 ? 48  ILE A CG1 1 
ATOM   87   C  CG2 . ILE A 1 60  ? 126.370 107.122 91.947  1.00 94.88 ? 48  ILE A CG2 1 
ATOM   88   C  CD1 . ILE A 1 60  ? 123.694 109.862 91.224  1.00 94.88 ? 48  ILE A CD1 1 
ATOM   89   N  N   . ASP A 1 61  ? 125.934 107.199 95.059  1.00 94.65 ? 49  ASP A N   1 
ATOM   90   C  CA  . ASP A 1 61  ? 125.521 106.112 95.938  1.00 94.65 ? 49  ASP A CA  1 
ATOM   91   C  C   . ASP A 1 61  ? 124.592 106.638 97.022  1.00 94.65 ? 49  ASP A C   1 
ATOM   92   O  O   . ASP A 1 61  ? 123.722 105.915 97.501  1.00 94.65 ? 49  ASP A O   1 
ATOM   93   C  CB  . ASP A 1 61  ? 126.743 105.446 96.562  1.00 94.65 ? 49  ASP A CB  1 
ATOM   94   C  CG  . ASP A 1 61  ? 126.511 103.989 96.903  1.00 94.65 ? 49  ASP A CG  1 
ATOM   95   O  OD1 . ASP A 1 61  ? 125.421 103.465 96.591  1.00 94.65 ? 49  ASP A OD1 1 
ATOM   96   O  OD2 . ASP A 1 61  ? 127.425 103.366 97.481  1.00 94.65 ? 49  ASP A OD2 1 
ATOM   97   N  N   . PHE A 1 62  ? 124.784 107.892 97.418  1.00 95.58 ? 50  PHE A N   1 
ATOM   98   C  CA  . PHE A 1 62  ? 123.940 108.497 98.446  1.00 95.58 ? 50  PHE A CA  1 
ATOM   99   C  C   . PHE A 1 62  ? 122.645 108.990 97.837  1.00 95.58 ? 50  PHE A C   1 
ATOM   100  O  O   . PHE A 1 62  ? 121.570 108.711 98.358  1.00 95.58 ? 50  PHE A O   1 
ATOM   101  C  CB  . PHE A 1 62  ? 124.681 109.659 99.114  1.00 95.58 ? 50  PHE A CB  1 
ATOM   102  C  CG  . PHE A 1 62  ? 123.818 110.513 100.003 1.00 95.58 ? 50  PHE A CG  1 
ATOM   103  C  CD1 . PHE A 1 62  ? 123.464 110.082 101.271 1.00 95.58 ? 50  PHE A CD1 1 
ATOM   104  C  CD2 . PHE A 1 62  ? 123.378 111.758 99.578  1.00 95.58 ? 50  PHE A CD2 1 
ATOM   105  C  CE1 . PHE A 1 62  ? 122.679 110.868 102.093 1.00 95.58 ? 50  PHE A CE1 1 
ATOM   106  C  CE2 . PHE A 1 62  ? 122.589 112.546 100.392 1.00 95.58 ? 50  PHE A CE2 1 
ATOM   107  C  CZ  . PHE A 1 62  ? 122.240 112.102 101.653 1.00 95.58 ? 50  PHE A CZ  1 
ATOM   108  N  N   . VAL A 1 63  ? 122.736 109.699 96.718  1.00 96.84 ? 51  VAL A N   1 
ATOM   109  C  CA  . VAL A 1 63  ? 121.542 110.279 96.117  1.00 96.84 ? 51  VAL A CA  1 
ATOM   110  C  C   . VAL A 1 63  ? 120.551 109.200 95.721  1.00 96.84 ? 51  VAL A C   1 
ATOM   111  O  O   . VAL A 1 63  ? 119.359 109.312 96.003  1.00 96.84 ? 51  VAL A O   1 
ATOM   112  C  CB  . VAL A 1 63  ? 121.922 111.111 94.878  1.00 96.84 ? 51  VAL A CB  1 
ATOM   113  C  CG1 . VAL A 1 63  ? 120.688 111.585 94.128  1.00 96.84 ? 51  VAL A CG1 1 
ATOM   114  C  CG2 . VAL A 1 63  ? 122.792 112.289 95.283  1.00 96.84 ? 51  VAL A CG2 1 
ATOM   115  N  N   . LEU A 1 64  ? 121.044 108.126 95.121  1.00 96.29 ? 52  LEU A N   1 
ATOM   116  C  CA  . LEU A 1 64  ? 120.167 107.036 94.729  1.00 96.29 ? 52  LEU A CA  1 
ATOM   117  C  C   . LEU A 1 64  ? 119.513 106.388 95.937  1.00 96.29 ? 52  LEU A C   1 
ATOM   118  O  O   . LEU A 1 64  ? 118.328 106.073 95.904  1.00 96.29 ? 52  LEU A O   1 
ATOM   119  C  CB  . LEU A 1 64  ? 120.936 105.992 93.922  1.00 96.29 ? 52  LEU A CB  1 
ATOM   120  C  CG  . LEU A 1 64  ? 121.489 106.479 92.584  1.00 96.29 ? 52  LEU A CG  1 
ATOM   121  C  CD1 . LEU A 1 64  ? 122.465 105.473 91.995  1.00 96.29 ? 52  LEU A CD1 1 
ATOM   122  C  CD2 . LEU A 1 64  ? 120.370 106.806 91.609  1.00 96.29 ? 52  LEU A CD2 1 
ATOM   123  N  N   . SER A 1 65  ? 120.279 106.185 97.004  1.00 95.89 ? 53  SER A N   1 
ATOM   124  C  CA  . SER A 1 65  ? 119.735 105.533 98.189  1.00 95.89 ? 53  SER A CA  1 
ATOM   125  C  C   . SER A 1 65  ? 118.625 106.343 98.838  1.00 95.89 ? 53  SER A C   1 
ATOM   126  O  O   . SER A 1 65  ? 117.595 105.791 99.219  1.00 95.89 ? 53  SER A O   1 
ATOM   127  C  CB  . SER A 1 65  ? 120.839 105.264 99.208  1.00 95.89 ? 53  SER A CB  1 
ATOM   128  O  OG  . SER A 1 65  ? 120.336 104.540 100.316 1.00 95.89 ? 53  SER A OG  1 
ATOM   129  N  N   . VAL A 1 66  ? 118.823 107.651 98.966  1.00 96.75 ? 54  VAL A N   1 
ATOM   130  C  CA  . VAL A 1 66  ? 117.781 108.509 99.527  1.00 96.75 ? 54  VAL A CA  1 
ATOM   131  C  C   . VAL A 1 66  ? 116.563 108.549 98.611  1.00 96.75 ? 54  VAL A C   1 
ATOM   132  O  O   . VAL A 1 66  ? 115.428 108.534 99.079  1.00 96.75 ? 54  VAL A O   1 
ATOM   133  C  CB  . VAL A 1 66  ? 118.305 109.920 99.845  1.00 96.75 ? 54  VAL A CB  1 
ATOM   134  C  CG1 . VAL A 1 66  ? 117.291 110.693 100.665 1.00 96.75 ? 54  VAL A CG1 1 
ATOM   135  C  CG2 . VAL A 1 66  ? 119.589 109.817 100.639 1.00 96.75 ? 54  VAL A CG2 1 
ATOM   136  N  N   . ALA A 1 67  ? 116.795 108.588 97.301  1.00 96.06 ? 55  ALA A N   1 
ATOM   137  C  CA  . ALA A 1 67  ? 115.687 108.594 96.354  1.00 96.06 ? 55  ALA A CA  1 
ATOM   138  C  C   . ALA A 1 67  ? 114.892 107.315 96.488  1.00 96.06 ? 55  ALA A C   1 
ATOM   139  O  O   . ALA A 1 67  ? 113.671 107.344 96.470  1.00 96.06 ? 55  ALA A O   1 
ATOM   140  C  CB  . ALA A 1 67  ? 116.198 108.751 94.935  1.00 96.06 ? 55  ALA A CB  1 
ATOM   141  N  N   . GLY A 1 68  ? 115.575 106.187 96.637  1.00 93.88 ? 56  GLY A N   1 
ATOM   142  C  CA  . GLY A 1 68  ? 114.885 104.928 96.847  1.00 93.88 ? 56  GLY A CA  1 
ATOM   143  C  C   . GLY A 1 68  ? 114.122 104.966 98.150  1.00 93.88 ? 56  GLY A C   1 
ATOM   144  O  O   . GLY A 1 68  ? 113.006 104.456 98.232  1.00 93.88 ? 56  GLY A O   1 
ATOM   145  N  N   . GLY A 1 69  ? 114.690 105.616 99.159  1.00 92.63 ? 57  GLY A N   1 
ATOM   146  C  CA  . GLY A 1 69  ? 114.022 105.736 100.444 1.00 92.63 ? 57  GLY A CA  1 
ATOM   147  C  C   . GLY A 1 69  ? 112.685 106.447 100.384 1.00 92.63 ? 57  GLY A C   1 
ATOM   148  O  O   . GLY A 1 69  ? 111.669 105.885 100.786 1.00 92.63 ? 57  GLY A O   1 
ATOM   149  N  N   . PHE A 1 70  ? 112.671 107.686 99.902  1.00 91.79 ? 58  PHE A N   1 
ATOM   150  C  CA  . PHE A 1 70  ? 111.424 108.449 99.877  1.00 91.79 ? 58  PHE A CA  1 
ATOM   151  C  C   . PHE A 1 70  ? 110.559 108.345 98.619  1.00 91.79 ? 58  PHE A C   1 
ATOM   152  O  O   . PHE A 1 70  ? 109.480 108.917 98.574  1.00 91.79 ? 58  PHE A O   1 
ATOM   153  C  CB  . PHE A 1 70  ? 111.634 109.919 100.285 1.00 91.79 ? 58  PHE A CB  1 
ATOM   154  C  CG  . PHE A 1 70  ? 112.599 110.680 99.425  1.00 91.79 ? 58  PHE A CG  1 
ATOM   155  C  CD1 . PHE A 1 70  ? 112.183 111.334 98.281  1.00 91.79 ? 58  PHE A CD1 1 
ATOM   156  C  CD2 . PHE A 1 70  ? 113.921 110.783 99.798  1.00 91.79 ? 58  PHE A CD2 1 
ATOM   157  C  CE1 . PHE A 1 70  ? 113.066 112.041 97.505  1.00 91.79 ? 58  PHE A CE1 1 
ATOM   158  C  CE2 . PHE A 1 70  ? 114.812 111.494 99.029  1.00 91.79 ? 58  PHE A CE2 1 
ATOM   159  C  CZ  . PHE A 1 70  ? 114.383 112.116 97.880  1.00 91.79 ? 58  PHE A CZ  1 
ATOM   160  N  N   . VAL A 1 71  ? 111.024 107.665 97.579  1.00 93.56 ? 59  VAL A N   1 
ATOM   161  C  CA  . VAL A 1 71  ? 110.161 107.478 96.416  1.00 93.56 ? 59  VAL A CA  1 
ATOM   162  C  C   . VAL A 1 71  ? 109.696 106.039 96.440  1.00 93.56 ? 59  VAL A C   1 
ATOM   163  O  O   . VAL A 1 71  ? 110.513 105.120 96.411  1.00 93.56 ? 59  VAL A O   1 
ATOM   164  C  CB  . VAL A 1 71  ? 110.834 107.841 95.078  1.00 93.56 ? 59  VAL A CB  1 
ATOM   165  C  CG1 . VAL A 1 71  ? 109.927 107.481 93.912  1.00 93.56 ? 59  VAL A CG1 1 
ATOM   166  C  CG2 . VAL A 1 71  ? 111.160 109.324 95.028  1.00 93.56 ? 59  VAL A CG2 1 
ATOM   167  N  N   . GLY A 1 72  ? 108.389 105.834 96.520  1.00 92.94 ? 60  GLY A N   1 
ATOM   168  C  CA  . GLY A 1 72  ? 107.864 104.492 96.624  1.00 92.94 ? 60  GLY A CA  1 
ATOM   169  C  C   . GLY A 1 72  ? 106.359 104.540 96.620  1.00 92.94 ? 60  GLY A C   1 
ATOM   170  O  O   . GLY A 1 72  ? 105.767 105.392 95.964  1.00 92.94 ? 60  GLY A O   1 
ATOM   171  N  N   . LEU A 1 73  ? 105.733 103.632 97.354  1.00 91.30 ? 61  LEU A N   1 
ATOM   172  C  CA  . LEU A 1 73  ? 104.284 103.587 97.385  1.00 91.30 ? 61  LEU A CA  1 
ATOM   173  C  C   . LEU A 1 73  ? 103.695 104.751 98.147  1.00 91.30 ? 61  LEU A C   1 
ATOM   174  O  O   . LEU A 1 73  ? 102.504 104.991 98.072  1.00 91.30 ? 61  LEU A O   1 
ATOM   175  C  CB  . LEU A 1 73  ? 103.814 102.275 98.003  1.00 91.30 ? 61  LEU A CB  1 
ATOM   176  C  CG  . LEU A 1 73  ? 104.245 101.006 97.274  1.00 91.30 ? 61  LEU A CG  1 
ATOM   177  C  CD1 . LEU A 1 73  ? 103.888 99.784  98.100  1.00 91.30 ? 61  LEU A CD1 1 
ATOM   178  C  CD2 . LEU A 1 73  ? 103.603 100.936 95.899  1.00 91.30 ? 61  LEU A CD2 1 
ATOM   179  N  N   . GLY A 1 74  ? 104.504 105.475 98.904  1.00 89.90 ? 62  GLY A N   1 
ATOM   180  C  CA  . GLY A 1 74  ? 103.966 106.650 99.558  1.00 89.90 ? 62  GLY A CA  1 
ATOM   181  C  C   . GLY A 1 74  ? 103.517 107.660 98.529  1.00 89.90 ? 62  GLY A C   1 
ATOM   182  O  O   . GLY A 1 74  ? 102.430 108.216 98.647  1.00 89.90 ? 62  GLY A O   1 
ATOM   183  N  N   . ASN A 1 75  ? 104.342 107.919 97.518  1.00 93.74 ? 63  ASN A N   1 
ATOM   184  C  CA  . ASN A 1 75  ? 103.920 108.806 96.444  1.00 93.74 ? 63  ASN A CA  1 
ATOM   185  C  C   . ASN A 1 75  ? 102.842 108.213 95.559  1.00 93.74 ? 63  ASN A C   1 
ATOM   186  O  O   . ASN A 1 75  ? 101.847 108.867 95.267  1.00 93.74 ? 63  ASN A O   1 
ATOM   187  C  CB  . ASN A 1 75  ? 105.121 109.140 95.569  1.00 93.74 ? 63  ASN A CB  1 
ATOM   188  C  CG  . ASN A 1 75  ? 106.220 109.840 96.332  1.00 93.74 ? 63  ASN A CG  1 
ATOM   189  O  OD1 . ASN A 1 75  ? 105.963 110.535 97.310  1.00 93.74 ? 63  ASN A OD1 1 
ATOM   190  N  ND2 . ASN A 1 75  ? 107.455 109.670 95.879  1.00 93.74 ? 63  ASN A ND2 1 
ATOM   191  N  N   . VAL A 1 76  ? 103.023 106.964 95.155  1.00 90.81 ? 64  VAL A N   1 
ATOM   192  C  CA  . VAL A 1 76  ? 102.055 106.323 94.274  1.00 90.81 ? 64  VAL A CA  1 
ATOM   193  C  C   . VAL A 1 76  ? 100.758 105.939 94.982  1.00 90.81 ? 64  VAL A C   1 
ATOM   194  O  O   . VAL A 1 76  ? 99.708  106.464 94.660  1.00 90.81 ? 64  VAL A O   1 
ATOM   195  C  CB  . VAL A 1 76  ? 102.653 105.086 93.583  1.00 90.81 ? 64  VAL A CB  1 
ATOM   196  C  CG1 . VAL A 1 76  ? 101.715 104.590 92.496  1.00 90.81 ? 64  VAL A CG1 1 
ATOM   197  C  CG2 . VAL A 1 76  ? 104.010 105.426 92.989  1.00 90.81 ? 64  VAL A CG2 1 
ATOM   198  N  N   . TRP A 1 77  ? 100.809 104.964 95.879  1.00 85.00 ? 65  TRP A N   1 
ATOM   199  C  CA  . TRP A 1 77  ? 99.614  104.560 96.616  1.00 85.00 ? 65  TRP A CA  1 
ATOM   200  C  C   . TRP A 1 77  ? 99.010  105.529 97.646  1.00 85.00 ? 65  TRP A C   1 
ATOM   201  O  O   . TRP A 1 77  ? 97.806  105.775 97.618  1.00 85.00 ? 65  TRP A O   1 
ATOM   202  C  CB  . TRP A 1 77  ? 99.897  103.200 97.276  1.00 85.00 ? 65  TRP A CB  1 
ATOM   203  C  CG  . TRP A 1 77  ? 99.008  102.847 98.411  1.00 85.00 ? 65  TRP A CG  1 
ATOM   204  C  CD1 . TRP A 1 77  ? 97.769  102.304 98.332  1.00 85.00 ? 65  TRP A CD1 1 
ATOM   205  C  CD2 . TRP A 1 77  ? 99.298  102.991 99.807  1.00 85.00 ? 65  TRP A CD2 1 
ATOM   206  N  NE1 . TRP A 1 77  ? 97.257  102.110 99.589  1.00 85.00 ? 65  TRP A NE1 1 
ATOM   207  C  CE2 . TRP A 1 77  ? 98.176  102.527 100.513 1.00 85.00 ? 65  TRP A CE2 1 
ATOM   208  C  CE3 . TRP A 1 77  ? 100.392 103.477 100.526 1.00 85.00 ? 65  TRP A CE3 1 
ATOM   209  C  CZ2 . TRP A 1 77  ? 98.114  102.532 101.900 1.00 85.00 ? 65  TRP A CZ2 1 
ATOM   210  C  CZ3 . TRP A 1 77  ? 100.328 103.483 101.904 1.00 85.00 ? 65  TRP A CZ3 1 
ATOM   211  C  CH2 . TRP A 1 77  ? 99.199  103.011 102.577 1.00 85.00 ? 65  TRP A CH2 1 
ATOM   212  N  N   . ARG A 1 78  ? 99.815  106.089 98.545  1.00 88.97 ? 66  ARG A N   1 
ATOM   213  C  CA  . ARG A 1 78  ? 99.252  106.918 99.629  1.00 88.97 ? 66  ARG A CA  1 
ATOM   214  C  C   . ARG A 1 78  ? 98.723  108.300 99.291  1.00 88.97 ? 66  ARG A C   1 
ATOM   215  O  O   . ARG A 1 78  ? 97.618  108.644 99.694  1.00 88.97 ? 66  ARG A O   1 
ATOM   216  C  CB  . ARG A 1 78  ? 100.220 107.018 100.807 1.00 88.97 ? 66  ARG A CB  1 
ATOM   217  C  CG  . ARG A 1 78  ? 99.584  107.567 102.071 1.00 88.97 ? 66  ARG A CG  1 
ATOM   218  C  CD  . ARG A 1 78  ? 100.012 106.787 103.300 1.00 88.97 ? 66  ARG A CD  1 
ATOM   219  N  NE  . ARG A 1 78  ? 99.030  106.888 104.372 1.00 88.97 ? 66  ARG A NE  1 
ATOM   220  C  CZ  . ARG A 1 78  ? 99.073  107.790 105.346 1.00 88.97 ? 66  ARG A CZ  1 
ATOM   221  N  NH1 . ARG A 1 78  ? 100.060 108.673 105.395 1.00 88.97 ? 66  ARG A NH1 1 
ATOM   222  N  NH2 . ARG A 1 78  ? 98.127  107.804 106.273 1.00 88.97 ? 66  ARG A NH2 1 
ATOM   223  N  N   . PHE A 1 79  ? 99.480  109.104 98.561  1.00 93.91 ? 67  PHE A N   1 
ATOM   224  C  CA  . PHE A 1 79  ? 99.022  110.466 98.320  1.00 93.91 ? 67  PHE A CA  1 
ATOM   225  C  C   . PHE A 1 79  ? 97.695  110.522 97.577  1.00 93.91 ? 67  PHE A C   1 
ATOM   226  O  O   . PHE A 1 79  ? 96.811  111.279 97.969  1.00 93.91 ? 67  PHE A O   1 
ATOM   227  C  CB  . PHE A 1 79  ? 100.082 111.290 97.588  1.00 93.91 ? 67  PHE A CB  1 
ATOM   228  C  CG  . PHE A 1 79  ? 99.615  112.657 97.182  1.00 93.91 ? 67  PHE A CG  1 
ATOM   229  C  CD1 . PHE A 1 79  ? 99.570  113.688 98.101  1.00 93.91 ? 67  PHE A CD1 1 
ATOM   230  C  CD2 . PHE A 1 79  ? 99.240  112.916 95.875  1.00 93.91 ? 67  PHE A CD2 1 
ATOM   231  C  CE1 . PHE A 1 79  ? 99.148  114.948 97.728  1.00 93.91 ? 67  PHE A CE1 1 
ATOM   232  C  CE2 . PHE A 1 79  ? 98.815  114.171 95.499  1.00 93.91 ? 67  PHE A CE2 1 
ATOM   233  C  CZ  . PHE A 1 79  ? 98.769  115.190 96.426  1.00 93.91 ? 67  PHE A CZ  1 
ATOM   234  N  N   . PRO A 1 80  ? 97.518  109.700 96.529  1.00 92.04 ? 68  PRO A N   1 
ATOM   235  C  CA  . PRO A 1 80  ? 96.194  109.765 95.915  1.00 92.04 ? 68  PRO A CA  1 
ATOM   236  C  C   . PRO A 1 80  ? 95.082  109.358 96.870  1.00 92.04 ? 68  PRO A C   1 
ATOM   237  O  O   . PRO A 1 80  ? 94.038  110.001 96.874  1.00 92.04 ? 68  PRO A O   1 
ATOM   238  C  CB  . PRO A 1 80  ? 96.312  108.770 94.774  1.00 92.04 ? 68  PRO A CB  1 
ATOM   239  C  CG  . PRO A 1 80  ? 97.711  108.959 94.322  1.00 92.04 ? 68  PRO A CG  1 
ATOM   240  C  CD  . PRO A 1 80  ? 98.491  109.100 95.599  1.00 92.04 ? 68  PRO A CD  1 
ATOM   241  N  N   . TYR A 1 81  ? 95.296  108.324 97.672  1.00 87.77 ? 69  TYR A N   1 
ATOM   242  C  CA  . TYR A 1 81  ? 94.248  107.856 98.564  1.00 87.77 ? 69  TYR A CA  1 
ATOM   243  C  C   . TYR A 1 81  ? 93.864  108.919 99.580  1.00 87.77 ? 69  TYR A C   1 
ATOM   244  O  O   . TYR A 1 81  ? 92.681  109.142 99.824  1.00 87.77 ? 69  TYR A O   1 
ATOM   245  C  CB  . TYR A 1 81  ? 94.654  106.516 99.207  1.00 87.77 ? 69  TYR A CB  1 
ATOM   246  C  CG  . TYR A 1 81  ? 94.849  106.448 100.715 1.00 87.77 ? 69  TYR A CG  1 
ATOM   247  C  CD1 . TYR A 1 81  ? 93.781  106.582 101.595 1.00 87.77 ? 69  TYR A CD1 1 
ATOM   248  C  CD2 . TYR A 1 81  ? 96.092  106.169 101.251 1.00 87.77 ? 69  TYR A CD2 1 
ATOM   249  C  CE1 . TYR A 1 81  ? 93.959  106.495 102.959 1.00 87.77 ? 69  TYR A CE1 1 
ATOM   250  C  CE2 . TYR A 1 81  ? 96.279  106.079 102.614 1.00 87.77 ? 69  TYR A CE2 1 
ATOM   251  C  CZ  . TYR A 1 81  ? 95.209  106.242 103.463 1.00 87.77 ? 69  TYR A CZ  1 
ATOM   252  O  OH  . TYR A 1 81  ? 95.389  106.153 104.822 1.00 87.77 ? 69  TYR A OH  1 
ATOM   253  N  N   . LEU A 1 82  ? 94.848  109.584 100.171 1.00 91.52 ? 70  LEU A N   1 
ATOM   254  C  CA  . LEU A 1 82  ? 94.562  110.608 101.164 1.00 91.52 ? 70  LEU A CA  1 
ATOM   255  C  C   . LEU A 1 82  ? 93.919  111.814 100.508 1.00 91.52 ? 70  LEU A C   1 
ATOM   256  O  O   . LEU A 1 82  ? 93.018  112.422 101.075 1.00 91.52 ? 70  LEU A O   1 
ATOM   257  C  CB  . LEU A 1 82  ? 95.830  111.012 101.897 1.00 91.52 ? 70  LEU A CB  1 
ATOM   258  C  CG  . LEU A 1 82  ? 96.280  110.063 102.998 1.00 91.52 ? 70  LEU A CG  1 
ATOM   259  C  CD1 . LEU A 1 82  ? 97.563  110.583 103.615 1.00 91.52 ? 70  LEU A CD1 1 
ATOM   260  C  CD2 . LEU A 1 82  ? 95.193  109.956 104.052 1.00 91.52 ? 70  LEU A CD2 1 
ATOM   261  N  N   . CYS A 1 83  ? 94.376  112.162 99.312  1.00 93.47 ? 71  CYS A N   1 
ATOM   262  C  CA  . CYS A 1 83  ? 93.813  113.294 98.589  1.00 93.47 ? 71  CYS A CA  1 
ATOM   263  C  C   . CYS A 1 83  ? 92.357  113.040 98.253  1.00 93.47 ? 71  CYS A C   1 
ATOM   264  O  O   . CYS A 1 83  ? 91.530  113.935 98.369  1.00 93.47 ? 71  CYS A O   1 
ATOM   265  C  CB  . CYS A 1 83  ? 94.610  113.527 97.312  1.00 93.47 ? 71  CYS A CB  1 
ATOM   266  S  SG  . CYS A 1 83  ? 94.442  115.159 96.569  1.00 93.47 ? 71  CYS A SG  1 
ATOM   267  N  N   . TYR A 1 84  ? 92.037  111.820 97.848  1.00 89.00 ? 72  TYR A N   1 
ATOM   268  C  CA  . TYR A 1 84  ? 90.669  111.465 97.484  1.00 89.00 ? 72  TYR A CA  1 
ATOM   269  C  C   . TYR A 1 84  ? 89.751  111.538 98.688  1.00 89.00 ? 72  TYR A C   1 
ATOM   270  O  O   . TYR A 1 84  ? 88.654  112.087 98.600  1.00 89.00 ? 72  TYR A O   1 
ATOM   271  C  CB  . TYR A 1 84  ? 90.689  110.039 96.947  1.00 89.00 ? 72  TYR A CB  1 
ATOM   272  C  CG  . TYR A 1 84  ? 89.469  109.580 96.195  1.00 89.00 ? 72  TYR A CG  1 
ATOM   273  C  CD1 . TYR A 1 84  ? 89.008  110.272 95.087  1.00 89.00 ? 72  TYR A CD1 1 
ATOM   274  C  CD2 . TYR A 1 84  ? 88.811  108.419 96.564  1.00 89.00 ? 72  TYR A CD2 1 
ATOM   275  C  CE1 . TYR A 1 84  ? 87.902  109.835 94.389  1.00 89.00 ? 72  TYR A CE1 1 
ATOM   276  C  CE2 . TYR A 1 84  ? 87.707  107.974 95.873  1.00 89.00 ? 72  TYR A CE2 1 
ATOM   277  C  CZ  . TYR A 1 84  ? 87.259  108.684 94.786  1.00 89.00 ? 72  TYR A CZ  1 
ATOM   278  O  OH  . TYR A 1 84  ? 86.159  108.236 94.099  1.00 89.00 ? 72  TYR A OH  1 
ATOM   279  N  N   . LYS A 1 85  ? 90.192  110.990 99.813  1.00 87.31 ? 73  LYS A N   1 
ATOM   280  C  CA  . LYS A 1 85  ? 89.381  110.972 101.018 1.00 87.31 ? 73  LYS A CA  1 
ATOM   281  C  C   . LYS A 1 85  ? 89.166  112.392 101.515 1.00 87.31 ? 73  LYS A C   1 
ATOM   282  O  O   . LYS A 1 85  ? 88.152  112.687 102.147 1.00 87.31 ? 73  LYS A O   1 
ATOM   283  C  CB  . LYS A 1 85  ? 90.077  110.126 102.083 1.00 87.31 ? 73  LYS A CB  1 
ATOM   284  C  CG  . LYS A 1 85  ? 89.214  109.760 103.276 1.00 87.31 ? 73  LYS A CG  1 
ATOM   285  C  CD  . LYS A 1 85  ? 89.956  108.808 104.196 1.00 87.31 ? 73  LYS A CD  1 
ATOM   286  C  CE  . LYS A 1 85  ? 91.299  109.384 104.607 1.00 87.31 ? 73  LYS A CE  1 
ATOM   287  N  NZ  . LYS A 1 85  ? 92.057  108.441 105.474 1.00 87.31 ? 73  LYS A NZ  1 
ATOM   288  N  N   . ASN A 1 86  ? 90.096  113.289 101.192 1.00 91.69 ? 74  ASN A N   1 
ATOM   289  C  CA  . ASN A 1 86  ? 89.999  114.676 101.649 1.00 91.69 ? 74  ASN A CA  1 
ATOM   290  C  C   . ASN A 1 86  ? 89.669  115.683 100.553 1.00 91.69 ? 74  ASN A C   1 
ATOM   291  O  O   . ASN A 1 86  ? 90.193  116.794 100.566 1.00 91.69 ? 74  ASN A O   1 
ATOM   292  C  CB  . ASN A 1 86  ? 91.282  115.086 102.364 1.00 91.69 ? 74  ASN A CB  1 
ATOM   293  C  CG  . ASN A 1 86  ? 91.482  114.348 103.669 1.00 91.69 ? 74  ASN A CG  1 
ATOM   294  O  OD1 . ASN A 1 86  ? 90.563  113.716 104.187 1.00 91.69 ? 74  ASN A OD1 1 
ATOM   295  N  ND2 . ASN A 1 86  ? 92.685  114.431 104.213 1.00 91.69 ? 74  ASN A ND2 1 
ATOM   296  N  N   . GLY A 1 87  ? 88.839  115.293 99.591  1.00 91.02 ? 75  GLY A N   1 
ATOM   297  C  CA  . GLY A 1 87  ? 88.394  116.208 98.546  1.00 91.02 ? 75  GLY A CA  1 
ATOM   298  C  C   . GLY A 1 87  ? 89.334  117.040 97.699  1.00 91.02 ? 75  GLY A C   1 
ATOM   299  O  O   . GLY A 1 87  ? 89.210  118.263 97.681  1.00 91.02 ? 75  GLY A O   1 
ATOM   300  N  N   . GLY A 1 88  ? 90.255  116.414 96.980  1.00 91.72 ? 76  GLY A N   1 
ATOM   301  C  CA  . GLY A 1 88  ? 91.105  117.162 96.065  1.00 91.72 ? 76  GLY A CA  1 
ATOM   302  C  C   . GLY A 1 88  ? 91.961  118.282 96.617  1.00 91.72 ? 76  GLY A C   1 
ATOM   303  O  O   . GLY A 1 88  ? 92.693  118.075 97.575  1.00 91.72 ? 76  GLY A O   1 
ATOM   304  N  N   . GLY A 1 89  ? 91.894  119.463 96.007  1.00 94.05 ? 77  GLY A N   1 
ATOM   305  C  CA  . GLY A 1 89  ? 92.727  120.585 96.426  1.00 94.05 ? 77  GLY A CA  1 
ATOM   306  C  C   . GLY A 1 89  ? 92.687  120.904 97.897  1.00 94.05 ? 77  GLY A C   1 
ATOM   307  O  O   . GLY A 1 89  ? 93.671  121.390 98.443  1.00 94.05 ? 77  GLY A O   1 
ATOM   308  N  N   . ALA A 1 90  ? 91.548  120.690 98.535  1.00 96.45 ? 78  ALA A N   1 
ATOM   309  C  CA  . ALA A 1 90  ? 91.454  120.876 99.967  1.00 96.45 ? 78  ALA A CA  1 
ATOM   310  C  C   . ALA A 1 90  ? 92.604  120.181 100.666 1.00 96.45 ? 78  ALA A C   1 
ATOM   311  O  O   . ALA A 1 90  ? 92.962  120.613 101.710 1.00 96.45 ? 78  ALA A O   1 
ATOM   312  C  CB  . ALA A 1 90  ? 90.125  120.377 100.489 1.00 96.45 ? 78  ALA A CB  1 
ATOM   313  N  N   . PHE A 1 91  ? 93.156  119.099 100.126 1.00 96.50 ? 79  PHE A N   1 
ATOM   314  C  CA  . PHE A 1 91  ? 94.332  118.417 100.671 1.00 96.50 ? 79  PHE A CA  1 
ATOM   315  C  C   . PHE A 1 91  ? 95.615  119.141 100.318 1.00 96.50 ? 79  PHE A C   1 
ATOM   316  O  O   . PHE A 1 91  ? 96.522  119.240 101.142 1.00 96.50 ? 79  PHE A O   1 
ATOM   317  C  CB  . PHE A 1 91  ? 94.387  116.986 100.146 1.00 96.50 ? 79  PHE A CB  1 
ATOM   318  C  CG  . PHE A 1 91  ? 95.405  116.116 100.824 1.00 96.50 ? 79  PHE A CG  1 
ATOM   319  C  CD1 . PHE A 1 91  ? 95.074  115.410 101.961 1.00 96.50 ? 79  PHE A CD1 1 
ATOM   320  C  CD2 . PHE A 1 91  ? 96.682  115.981 100.307 1.00 96.50 ? 79  PHE A CD2 1 
ATOM   321  C  CE1 . PHE A 1 91  ? 95.998  114.598 102.581 1.00 96.50 ? 79  PHE A CE1 1 
ATOM   322  C  CE2 . PHE A 1 91  ? 97.612  115.170 100.921 1.00 96.50 ? 79  PHE A CE2 1 
ATOM   323  C  CZ  . PHE A 1 91  ? 97.268  114.474 102.057 1.00 96.50 ? 79  PHE A CZ  1 
ATOM   324  N  N   . LEU A 1 92  ? 95.697  119.665 99.102  1.00 96.48 ? 80  LEU A N   1 
ATOM   325  C  CA  . LEU A 1 92  ? 96.933  120.296 98.643  1.00 96.48 ? 80  LEU A CA  1 
ATOM   326  C  C   . LEU A 1 92  ? 97.391  121.508 99.451  1.00 96.48 ? 80  LEU A C   1 
ATOM   327  O  O   . LEU A 1 92  ? 98.584  121.669 99.669  1.00 96.48 ? 80  LEU A O   1 
ATOM   328  C  CB  . LEU A 1 92  ? 96.818  120.664 97.163  1.00 96.48 ? 80  LEU A CB  1 
ATOM   329  C  CG  . LEU A 1 92  ? 96.763  119.477 96.205  1.00 96.48 ? 80  LEU A CG  1 
ATOM   330  C  CD1 . LEU A 1 92  ? 96.093  119.861 94.900  1.00 96.48 ? 80  LEU A CD1 1 
ATOM   331  C  CD2 . LEU A 1 92  ? 98.165  118.956 95.956  1.00 96.48 ? 80  LEU A CD2 1 
ATOM   332  N  N   . ILE A 1 93  ? 96.479  122.371 99.880  1.00 96.18 ? 81  ILE A N   1 
ATOM   333  C  CA  . ILE A 1 93  ? 96.938  123.558 100.587 1.00 96.18 ? 81  ILE A CA  1 
ATOM   334  C  C   . ILE A 1 93  ? 97.670  123.175 101.876 1.00 96.18 ? 81  ILE A C   1 
ATOM   335  O  O   . ILE A 1 93  ? 98.760  123.672 102.120 1.00 96.18 ? 81  ILE A O   1 
ATOM   336  C  CB  . ILE A 1 93  ? 95.798  124.575 100.835 1.00 96.18 ? 81  ILE A CB  1 
ATOM   337  C  CG1 . ILE A 1 93  ? 94.946  124.748 99.576  1.00 96.18 ? 81  ILE A CG1 1 
ATOM   338  C  CG2 . ILE A 1 93  ? 96.355  125.909 101.305 1.00 96.18 ? 81  ILE A CG2 1 
ATOM   339  C  CD1 . ILE A 1 93  ? 95.683  125.384 98.418  1.00 96.18 ? 81  ILE A CD1 1 
ATOM   340  N  N   . PRO A 1 94  ? 97.113  122.254 102.689 1.00 95.06 ? 82  PRO A N   1 
ATOM   341  C  CA  . PRO A 1 94  ? 97.902  121.811 103.842 1.00 95.06 ? 82  PRO A CA  1 
ATOM   342  C  C   . PRO A 1 94  ? 99.163  121.074 103.433 1.00 95.06 ? 82  PRO A C   1 
ATOM   343  O  O   . PRO A 1 94  ? 100.190 121.254 104.073 1.00 95.06 ? 82  PRO A O   1 
ATOM   344  C  CB  . PRO A 1 94  ? 96.953  120.867 104.553 1.00 95.06 ? 82  PRO A CB  1 
ATOM   345  C  CG  . PRO A 1 94  ? 95.634  121.501 104.345 1.00 95.06 ? 82  PRO A CG  1 
ATOM   346  C  CD  . PRO A 1 94  ? 95.680  122.007 102.932 1.00 95.06 ? 82  PRO A CD  1 
ATOM   347  N  N   . TYR A 1 95  ? 99.095  120.251 102.392 1.00 96.38 ? 83  TYR A N   1 
ATOM   348  C  CA  . TYR A 1 95  ? 100.249 119.451 101.996 1.00 96.38 ? 83  TYR A CA  1 
ATOM   349  C  C   . TYR A 1 95  ? 101.409 120.337 101.612 1.00 96.38 ? 83  TYR A C   1 
ATOM   350  O  O   . TYR A 1 95  ? 102.528 120.115 102.054 1.00 96.38 ? 83  TYR A O   1 
ATOM   351  C  CB  . TYR A 1 95  ? 99.860  118.584 100.800 1.00 96.38 ? 83  TYR A CB  1 
ATOM   352  C  CG  . TYR A 1 95  ? 100.935 117.670 100.262 1.00 96.38 ? 83  TYR A CG  1 
ATOM   353  C  CD1 . TYR A 1 95  ? 101.167 116.430 100.837 1.00 96.38 ? 83  TYR A CD1 1 
ATOM   354  C  CD2 . TYR A 1 95  ? 101.690 118.029 99.152  1.00 96.38 ? 83  TYR A CD2 1 
ATOM   355  C  CE1 . TYR A 1 95  ? 102.136 115.583 100.337 1.00 96.38 ? 83  TYR A CE1 1 
ATOM   356  C  CE2 . TYR A 1 95  ? 102.663 117.190 98.648  1.00 96.38 ? 83  TYR A CE2 1 
ATOM   357  C  CZ  . TYR A 1 95  ? 102.881 115.968 99.244  1.00 96.38 ? 83  TYR A CZ  1 
ATOM   358  O  OH  . TYR A 1 95  ? 103.848 115.125 98.748  1.00 96.38 ? 83  TYR A OH  1 
ATOM   359  N  N   . PHE A 1 96  ? 101.158 121.372 100.823 1.00 96.62 ? 84  PHE A N   1 
ATOM   360  C  CA  . PHE A 1 96  ? 102.227 122.288 100.436 1.00 96.62 ? 84  PHE A CA  1 
ATOM   361  C  C   . PHE A 1 96  ? 102.709 123.189 101.569 1.00 96.62 ? 84  PHE A C   1 
ATOM   362  O  O   . PHE A 1 96  ? 103.902 123.458 101.675 1.00 96.62 ? 84  PHE A O   1 
ATOM   363  C  CB  . PHE A 1 96  ? 101.847 123.104 99.205  1.00 96.62 ? 84  PHE A CB  1 
ATOM   364  C  CG  . PHE A 1 96  ? 101.869 122.310 97.934  1.00 96.62 ? 84  PHE A CG  1 
ATOM   365  C  CD1 . PHE A 1 96  ? 103.026 121.670 97.528  1.00 96.62 ? 84  PHE A CD1 1 
ATOM   366  C  CD2 . PHE A 1 96  ? 100.738 122.202 97.146  1.00 96.62 ? 84  PHE A CD2 1 
ATOM   367  C  CE1 . PHE A 1 96  ? 103.056 120.934 96.360  1.00 96.62 ? 84  PHE A CE1 1 
ATOM   368  C  CE2 . PHE A 1 96  ? 100.761 121.470 95.975  1.00 96.62 ? 84  PHE A CE2 1 
ATOM   369  C  CZ  . PHE A 1 96  ? 101.921 120.833 95.582  1.00 96.62 ? 84  PHE A CZ  1 
ATOM   370  N  N   . ILE A 1 97  ? 101.798 123.641 102.424 1.00 94.92 ? 85  ILE A N   1 
ATOM   371  C  CA  . ILE A 1 97  ? 102.201 124.461 103.556 1.00 94.92 ? 85  ILE A CA  1 
ATOM   372  C  C   . ILE A 1 97  ? 103.117 123.635 104.431 1.00 94.92 ? 85  ILE A C   1 
ATOM   373  O  O   . ILE A 1 97  ? 104.186 124.092 104.836 1.00 94.92 ? 85  ILE A O   1 
ATOM   374  C  CB  . ILE A 1 97  ? 100.982 124.916 104.382 1.00 94.92 ? 85  ILE A CB  1 
ATOM   375  C  CG1 . ILE A 1 97  ? 100.256 126.058 103.674 1.00 94.92 ? 85  ILE A CG1 1 
ATOM   376  C  CG2 . ILE A 1 97  ? 101.392 125.377 105.771 1.00 94.92 ? 85  ILE A CG2 1 
ATOM   377  C  CD1 . ILE A 1 97  ? 99.010  126.519 104.395 1.00 94.92 ? 85  ILE A CD1 1 
ATOM   378  N  N   . PHE A 1 98  ? 102.777 122.371 104.639 1.00 94.68 ? 86  PHE A N   1 
ATOM   379  C  CA  . PHE A 1 98  ? 103.667 121.506 105.402 1.00 94.68 ? 86  PHE A CA  1 
ATOM   380  C  C   . PHE A 1 98  ? 104.971 121.216 104.668 1.00 94.68 ? 86  PHE A C   1 
ATOM   381  O  O   . PHE A 1 98  ? 105.994 121.039 105.299 1.00 94.68 ? 86  PHE A O   1 
ATOM   382  C  CB  . PHE A 1 98  ? 102.978 120.201 105.785 1.00 94.68 ? 86  PHE A CB  1 
ATOM   383  C  CG  . PHE A 1 98  ? 102.275 120.253 107.110 1.00 94.68 ? 86  PHE A CG  1 
ATOM   384  C  CD1 . PHE A 1 98  ? 100.947 120.637 107.193 1.00 94.68 ? 86  PHE A CD1 1 
ATOM   385  C  CD2 . PHE A 1 98  ? 102.941 119.907 108.272 1.00 94.68 ? 86  PHE A CD2 1 
ATOM   386  C  CE1 . PHE A 1 98  ? 100.298 120.678 108.411 1.00 94.68 ? 86  PHE A CE1 1 
ATOM   387  C  CE2 . PHE A 1 98  ? 102.298 119.945 109.493 1.00 94.68 ? 86  PHE A CE2 1 
ATOM   388  C  CZ  . PHE A 1 98  ? 100.975 120.331 109.562 1.00 94.68 ? 86  PHE A CZ  1 
ATOM   389  N  N   . LEU A 1 99  ? 104.943 121.145 103.343 1.00 96.58 ? 87  LEU A N   1 
ATOM   390  C  CA  . LEU A 1 99  ? 106.153 120.789 102.594 1.00 96.58 ? 87  LEU A CA  1 
ATOM   391  C  C   . LEU A 1 99  ? 107.304 121.778 102.708 1.00 96.58 ? 87  LEU A C   1 
ATOM   392  O  O   . LEU A 1 99  ? 108.439 121.377 102.937 1.00 96.58 ? 87  LEU A O   1 
ATOM   393  C  CB  . LEU A 1 99  ? 105.808 120.582 101.117 1.00 96.58 ? 87  LEU A CB  1 
ATOM   394  C  CG  . LEU A 1 99  ? 106.939 120.495 100.096 1.00 96.58 ? 87  LEU A CG  1 
ATOM   395  C  CD1 . LEU A 1 99  ? 107.832 119.303 100.383 1.00 96.58 ? 87  LEU A CD1 1 
ATOM   396  C  CD2 . LEU A 1 99  ? 106.370 120.414 98.692  1.00 96.58 ? 87  LEU A CD2 1 
ATOM   397  N  N   . PHE A 1 100 ? 107.018 123.064 102.551 1.00 96.09 ? 88  PHE A N   1 
ATOM   398  C  CA  . PHE A 1 100 ? 108.068 124.072 102.602 1.00 96.09 ? 88  PHE A CA  1 
ATOM   399  C  C   . PHE A 1 100 ? 108.185 124.641 104.000 1.00 96.09 ? 88  PHE A C   1 
ATOM   400  O  O   . PHE A 1 100 ? 109.119 125.375 104.300 1.00 96.09 ? 88  PHE A O   1 
ATOM   401  C  CB  . PHE A 1 100 ? 107.783 125.194 101.610 1.00 96.09 ? 88  PHE A CB  1 
ATOM   402  C  CG  . PHE A 1 100 ? 107.595 124.725 100.199 1.00 96.09 ? 88  PHE A CG  1 
ATOM   403  C  CD1 . PHE A 1 100 ? 108.679 124.320 99.442  1.00 96.09 ? 88  PHE A CD1 1 
ATOM   404  C  CD2 . PHE A 1 100 ? 106.336 124.705 99.624  1.00 96.09 ? 88  PHE A CD2 1 
ATOM   405  C  CE1 . PHE A 1 100 ? 108.510 123.893 98.139  1.00 96.09 ? 88  PHE A CE1 1 
ATOM   406  C  CE2 . PHE A 1 100 ? 106.159 124.279 98.323  1.00 96.09 ? 88  PHE A CE2 1 
ATOM   407  C  CZ  . PHE A 1 100 ? 107.248 123.874 97.579  1.00 96.09 ? 88  PHE A CZ  1 
ATOM   408  N  N   . GLY A 1 101 ? 107.234 124.305 104.859 1.00 94.83 ? 89  GLY A N   1 
ATOM   409  C  CA  . GLY A 1 101 ? 107.262 124.803 106.219 1.00 94.83 ? 89  GLY A CA  1 
ATOM   410  C  C   . GLY A 1 101 ? 107.878 123.796 107.160 1.00 94.83 ? 89  GLY A C   1 
ATOM   411  O  O   . GLY A 1 101 ? 108.820 124.106 107.879 1.00 94.83 ? 89  GLY A O   1 
ATOM   412  N  N   . SER A 1 102 ? 107.346 122.583 107.163 1.00 94.89 ? 90  SER A N   1 
ATOM   413  C  CA  . SER A 1 102 ? 107.895 121.531 108.014 1.00 94.89 ? 90  SER A CA  1 
ATOM   414  C  C   . SER A 1 102 ? 108.667 120.429 107.305 1.00 94.89 ? 90  SER A C   1 
ATOM   415  O  O   . SER A 1 102 ? 109.787 120.132 107.683 1.00 94.89 ? 90  SER A O   1 
ATOM   416  C  CB  . SER A 1 102 ? 106.757 120.881 108.796 1.00 94.89 ? 90  SER A CB  1 
ATOM   417  O  OG  . SER A 1 102 ? 105.967 121.858 109.445 1.00 94.89 ? 90  SER A OG  1 
ATOM   418  N  N   . GLY A 1 103 ? 108.103 119.848 106.255 1.00 95.82 ? 91  GLY A N   1 
ATOM   419  C  CA  . GLY A 1 103 ? 108.739 118.723 105.588 1.00 95.82 ? 91  GLY A CA  1 
ATOM   420  C  C   . GLY A 1 103 ? 110.174 118.889 105.160 1.00 95.82 ? 91  GLY A C   1 
ATOM   421  O  O   . GLY A 1 103 ? 111.063 118.271 105.733 1.00 95.82 ? 91  GLY A O   1 
ATOM   422  N  N   . LEU A 1 104 ? 110.409 119.713 104.148 1.00 96.83 ? 92  LEU A N   1 
ATOM   423  C  CA  . LEU A 1 104 ? 111.761 119.880 103.626 1.00 96.83 ? 92  LEU A CA  1 
ATOM   424  C  C   . LEU A 1 104 ? 112.776 120.275 104.707 1.00 96.83 ? 92  LEU A C   1 
ATOM   425  O  O   . LEU A 1 104 ? 113.870 119.716 104.752 1.00 96.83 ? 92  LEU A O   1 
ATOM   426  C  CB  . LEU A 1 104 ? 111.800 120.831 102.424 1.00 96.83 ? 92  LEU A CB  1 
ATOM   427  C  CG  . LEU A 1 104 ? 111.565 120.207 101.052 1.00 96.83 ? 92  LEU A CG  1 
ATOM   428  C  CD1 . LEU A 1 104 ? 111.520 121.286 99.983  1.00 96.83 ? 92  LEU A CD1 1 
ATOM   429  C  CD2 . LEU A 1 104 ? 112.664 119.200 100.754 1.00 96.83 ? 92  LEU A CD2 1 
ATOM   430  N  N   . PRO A 1 105 ? 112.415 121.237 105.605 1.00 97.36 ? 93  PRO A N   1 
ATOM   431  C  CA  . PRO A 1 105 ? 113.398 121.488 106.665 1.00 97.36 ? 93  PRO A CA  1 
ATOM   432  C  C   . PRO A 1 105 ? 113.685 120.265 107.532 1.00 97.36 ? 93  PRO A C   1 
ATOM   433  O  O   . PRO A 1 105 ? 114.844 119.910 107.686 1.00 97.36 ? 93  PRO A O   1 
ATOM   434  C  CB  . PRO A 1 105 ? 112.734 122.577 107.491 1.00 97.36 ? 93  PRO A CB  1 
ATOM   435  C  CG  . PRO A 1 105 ? 112.005 123.370 106.479 1.00 97.36 ? 93  PRO A CG  1 
ATOM   436  C  CD  . PRO A 1 105 ? 111.398 122.321 105.603 1.00 97.36 ? 93  PRO A CD  1 
ATOM   437  N  N   . VAL A 1 106 ? 112.672 119.619 108.091 1.00 97.22 ? 94  VAL A N   1 
ATOM   438  C  CA  . VAL A 1 106 ? 112.937 118.496 108.997 1.00 97.22 ? 94  VAL A CA  1 
ATOM   439  C  C   . VAL A 1 106 ? 113.644 117.328 108.295 1.00 97.22 ? 94  VAL A C   1 
ATOM   440  O  O   . VAL A 1 106 ? 114.487 116.662 108.891 1.00 97.22 ? 94  VAL A O   1 
ATOM   441  C  CB  . VAL A 1 106 ? 111.690 118.040 109.781 1.00 97.22 ? 94  VAL A CB  1 
ATOM   442  C  CG1 . VAL A 1 106 ? 112.107 117.182 110.960 1.00 97.22 ? 94  VAL A CG1 1 
ATOM   443  C  CG2 . VAL A 1 106 ? 110.962 119.249 110.328 1.00 97.22 ? 94  VAL A CG2 1 
ATOM   444  N  N   . PHE A 1 107 ? 113.303 117.068 107.037 1.00 97.50 ? 95  PHE A N   1 
ATOM   445  C  CA  . PHE A 1 107 ? 113.964 115.997 106.303 1.00 97.50 ? 95  PHE A CA  1 
ATOM   446  C  C   . PHE A 1 107 ? 115.447 116.286 106.199 1.00 97.50 ? 95  PHE A C   1 
ATOM   447  O  O   . PHE A 1 107 ? 116.273 115.413 106.473 1.00 97.50 ? 95  PHE A O   1 
ATOM   448  C  CB  . PHE A 1 107 ? 113.347 115.870 104.908 1.00 97.50 ? 95  PHE A CB  1 
ATOM   449  C  CG  . PHE A 1 107 ? 114.257 115.257 103.881 1.00 97.50 ? 95  PHE A CG  1 
ATOM   450  C  CD1 . PHE A 1 107 ? 114.584 113.913 103.932 1.00 97.50 ? 95  PHE A CD1 1 
ATOM   451  C  CD2 . PHE A 1 107 ? 114.762 116.024 102.844 1.00 97.50 ? 95  PHE A CD2 1 
ATOM   452  C  CE1 . PHE A 1 107 ? 115.418 113.353 102.984 1.00 97.50 ? 95  PHE A CE1 1 
ATOM   453  C  CE2 . PHE A 1 107 ? 115.592 115.468 101.893 1.00 97.50 ? 95  PHE A CE2 1 
ATOM   454  C  CZ  . PHE A 1 107 ? 115.922 114.132 101.963 1.00 97.50 ? 95  PHE A CZ  1 
ATOM   455  N  N   . PHE A 1 108 ? 115.803 117.518 105.863 1.00 97.98 ? 96  PHE A N   1 
ATOM   456  C  CA  . PHE A 1 108 ? 117.215 117.870 105.831 1.00 97.98 ? 96  PHE A CA  1 
ATOM   457  C  C   . PHE A 1 108 ? 117.807 117.783 107.224 1.00 97.98 ? 96  PHE A C   1 
ATOM   458  O  O   . PHE A 1 108 ? 118.936 117.357 107.381 1.00 97.98 ? 96  PHE A O   1 
ATOM   459  C  CB  . PHE A 1 108 ? 117.492 119.224 105.185 1.00 97.98 ? 96  PHE A CB  1 
ATOM   460  C  CG  . PHE A 1 108 ? 118.956 119.518 105.040 1.00 97.98 ? 96  PHE A CG  1 
ATOM   461  C  CD1 . PHE A 1 108 ? 119.817 118.549 104.569 1.00 97.98 ? 96  PHE A CD1 1 
ATOM   462  C  CD2 . PHE A 1 108 ? 119.474 120.747 105.386 1.00 97.98 ? 96  PHE A CD2 1 
ATOM   463  C  CE1 . PHE A 1 108 ? 121.165 118.799 104.450 1.00 97.98 ? 96  PHE A CE1 1 
ATOM   464  C  CE2 . PHE A 1 108 ? 120.823 121.010 105.266 1.00 97.98 ? 96  PHE A CE2 1 
ATOM   465  C  CZ  . PHE A 1 108 ? 121.671 120.032 104.799 1.00 97.98 ? 96  PHE A CZ  1 
ATOM   466  N  N   . LEU A 1 109 ? 117.045 118.188 108.235 1.00 98.11 ? 97  LEU A N   1 
ATOM   467  C  CA  . LEU A 1 109 ? 117.538 118.162 109.609 1.00 98.11 ? 97  LEU A CA  1 
ATOM   468  C  C   . LEU A 1 109 ? 118.067 116.788 109.946 1.00 98.11 ? 97  LEU A C   1 
ATOM   469  O  O   . LEU A 1 109 ? 119.147 116.656 110.511 1.00 98.11 ? 97  LEU A O   1 
ATOM   470  C  CB  . LEU A 1 109 ? 116.438 118.552 110.593 1.00 98.11 ? 97  LEU A CB  1 
ATOM   471  C  CG  . LEU A 1 109 ? 116.743 118.485 112.089 1.00 98.11 ? 97  LEU A CG  1 
ATOM   472  C  CD1 . LEU A 1 109 ? 117.928 119.373 112.416 1.00 98.11 ? 97  LEU A CD1 1 
ATOM   473  C  CD2 . LEU A 1 109 ? 115.524 118.891 112.901 1.00 98.11 ? 97  LEU A CD2 1 
ATOM   474  N  N   . GLU A 1 110 ? 117.311 115.758 109.592 1.00 98.09 ? 98  GLU A N   1 
ATOM   475  C  CA  . GLU A 1 110 ? 117.727 114.399 109.903 1.00 98.09 ? 98  GLU A CA  1 
ATOM   476  C  C   . GLU A 1 110 ? 119.023 114.042 109.193 1.00 98.09 ? 98  GLU A C   1 
ATOM   477  O  O   . GLU A 1 110 ? 119.902 113.411 109.773 1.00 98.09 ? 98  GLU A O   1 
ATOM   478  C  CB  . GLU A 1 110 ? 116.612 113.411 109.585 1.00 98.09 ? 98  GLU A CB  1 
ATOM   479  C  CG  . GLU A 1 110 ? 115.415 113.568 110.506 1.00 98.09 ? 98  GLU A CG  1 
ATOM   480  C  CD  . GLU A 1 110 ? 114.450 112.407 110.420 1.00 98.09 ? 98  GLU A CD  1 
ATOM   481  O  OE1 . GLU A 1 110 ? 114.291 111.839 109.322 1.00 98.09 ? 98  GLU A OE1 1 
ATOM   482  O  OE2 . GLU A 1 110 ? 113.843 112.068 111.456 1.00 98.09 ? 98  GLU A OE2 1 
ATOM   483  N  N   . ILE A 1 111 ? 119.162 114.460 107.943 1.00 98.27 ? 99  ILE A N   1 
ATOM   484  C  CA  . ILE A 1 111 ? 120.406 114.216 107.234 1.00 98.27 ? 99  ILE A CA  1 
ATOM   485  C  C   . ILE A 1 111 ? 121.557 114.945 107.930 1.00 98.27 ? 99  ILE A C   1 
ATOM   486  O  O   . ILE A 1 111 ? 122.639 114.385 108.083 1.00 98.27 ? 99  ILE A O   1 
ATOM   487  C  CB  . ILE A 1 111 ? 120.304 114.654 105.764 1.00 98.27 ? 99  ILE A CB  1 
ATOM   488  C  CG1 . ILE A 1 111 ? 119.106 113.984 105.091 1.00 98.27 ? 99  ILE A CG1 1 
ATOM   489  C  CG2 . ILE A 1 111 ? 121.583 114.329 105.009 1.00 98.27 ? 99  ILE A CG2 1 
ATOM   490  C  CD1 . ILE A 1 111 ? 119.319 112.519 104.785 1.00 98.27 ? 99  ILE A CD1 1 
ATOM   491  N  N   . ILE A 1 112 ? 121.326 116.179 108.374 1.00 97.61 ? 100 ILE A N   1 
ATOM   492  C  CA  . ILE A 1 112 ? 122.393 116.950 108.999 1.00 97.61 ? 100 ILE A CA  1 
ATOM   493  C  C   . ILE A 1 112 ? 122.884 116.284 110.261 1.00 97.61 ? 100 ILE A C   1 
ATOM   494  O  O   . ILE A 1 112 ? 124.085 116.129 110.458 1.00 97.61 ? 100 ILE A O   1 
ATOM   495  C  CB  . ILE A 1 112 ? 121.892 118.324 109.458 1.00 97.61 ? 100 ILE A CB  1 
ATOM   496  C  CG1 . ILE A 1 112 ? 121.384 119.143 108.288 1.00 97.61 ? 100 ILE A CG1 1 
ATOM   497  C  CG2 . ILE A 1 112 ? 122.988 119.095 110.173 1.00 97.61 ? 100 ILE A CG2 1 
ATOM   498  C  CD1 . ILE A 1 112 ? 120.481 120.267 108.732 1.00 97.61 ? 100 ILE A CD1 1 
ATOM   499  N  N   . ILE A 1 113 ? 121.956 115.849 111.107 1.00 96.95 ? 101 ILE A N   1 
ATOM   500  C  CA  . ILE A 1 113 ? 122.364 115.249 112.369 1.00 96.95 ? 101 ILE A CA  1 
ATOM   501  C  C   . ILE A 1 113 ? 123.123 113.976 112.058 1.00 96.95 ? 101 ILE A C   1 
ATOM   502  O  O   . ILE A 1 113 ? 124.117 113.679 112.702 1.00 96.95 ? 101 ILE A O   1 
ATOM   503  C  CB  . ILE A 1 113 ? 121.224 115.084 113.404 1.00 96.95 ? 101 ILE A CB  1 
ATOM   504  C  CG1 . ILE A 1 113 ? 120.006 114.396 112.804 1.00 96.95 ? 101 ILE A CG1 1 
ATOM   505  C  CG2 . ILE A 1 113 ? 120.820 116.439 113.959 1.00 96.95 ? 101 ILE A CG2 1 
ATOM   506  C  CD1 . ILE A 1 113 ? 118.793 114.414 113.707 1.00 96.95 ? 101 ILE A CD1 1 
ATOM   507  N  N   . GLY A 1 114 ? 122.674 113.234 111.055 1.00 97.29 ? 102 GLY A N   1 
ATOM   508  C  CA  . GLY A 1 114 ? 123.408 112.055 110.650 1.00 97.29 ? 102 GLY A CA  1 
ATOM   509  C  C   . GLY A 1 114 ? 124.836 112.408 110.281 1.00 97.29 ? 102 GLY A C   1 
ATOM   510  O  O   . GLY A 1 114 ? 125.765 111.808 110.803 1.00 97.29 ? 102 GLY A O   1 
ATOM   511  N  N   . GLN A 1 115 ? 125.038 113.393 109.418 1.00 96.08 ? 103 GLN A N   1 
ATOM   512  C  CA  . GLN A 1 115 ? 126.399 113.799 109.097 1.00 96.08 ? 103 GLN A CA  1 
ATOM   513  C  C   . GLN A 1 115 ? 127.189 114.222 110.331 1.00 96.08 ? 103 GLN A C   1 
ATOM   514  O  O   . GLN A 1 115 ? 128.283 113.712 110.565 1.00 96.08 ? 103 GLN A O   1 
ATOM   515  C  CB  . GLN A 1 115 ? 126.418 114.904 108.040 1.00 96.08 ? 103 GLN A CB  1 
ATOM   516  C  CG  . GLN A 1 115 ? 126.023 114.440 106.650 1.00 96.08 ? 103 GLN A CG  1 
ATOM   517  C  CD  . GLN A 1 115 ? 126.453 115.412 105.571 1.00 96.08 ? 103 GLN A CD  1 
ATOM   518  O  OE1 . GLN A 1 115 ? 126.199 115.196 104.388 1.00 96.08 ? 103 GLN A OE1 1 
ATOM   519  N  NE2 . GLN A 1 115 ? 127.117 116.488 105.975 1.00 96.08 ? 103 GLN A NE2 1 
ATOM   520  N  N   . TYR A 1 116 ? 126.658 115.156 111.112 1.00 94.24 ? 104 TYR A N   1 
ATOM   521  C  CA  . TYR A 1 116 ? 127.405 115.662 112.262 1.00 94.24 ? 104 TYR A CA  1 
ATOM   522  C  C   . TYR A 1 116 ? 127.696 114.629 113.346 1.00 94.24 ? 104 TYR A C   1 
ATOM   523  O  O   . TYR A 1 116 ? 128.835 114.500 113.789 1.00 94.24 ? 104 TYR A O   1 
ATOM   524  C  CB  . TYR A 1 116 ? 126.613 116.817 112.880 1.00 94.24 ? 104 TYR A CB  1 
ATOM   525  C  CG  . TYR A 1 116 ? 127.386 117.686 113.838 1.00 94.24 ? 104 TYR A CG  1 
ATOM   526  C  CD1 . TYR A 1 116 ? 128.204 118.703 113.371 1.00 94.24 ? 104 TYR A CD1 1 
ATOM   527  C  CD2 . TYR A 1 116 ? 127.279 117.507 115.209 1.00 94.24 ? 104 TYR A CD2 1 
ATOM   528  C  CE1 . TYR A 1 116 ? 128.908 119.509 114.242 1.00 94.24 ? 104 TYR A CE1 1 
ATOM   529  C  CE2 . TYR A 1 116 ? 127.981 118.306 116.088 1.00 94.24 ? 104 TYR A CE2 1 
ATOM   530  C  CZ  . TYR A 1 116 ? 128.793 119.306 115.598 1.00 94.24 ? 104 TYR A CZ  1 
ATOM   531  O  OH  . TYR A 1 116 ? 129.494 120.108 116.468 1.00 94.24 ? 104 TYR A OH  1 
ATOM   532  N  N   . THR A 1 117 ? 126.683 113.883 113.767 1.00 93.35 ? 105 THR A N   1 
ATOM   533  C  CA  . THR A 1 117 ? 126.879 112.833 114.769 1.00 93.35 ? 105 THR A CA  1 
ATOM   534  C  C   . THR A 1 117 ? 127.650 111.647 114.250 1.00 93.35 ? 105 THR A C   1 
ATOM   535  O  O   . THR A 1 117 ? 128.406 111.036 115.004 1.00 93.35 ? 105 THR A O   1 
ATOM   536  C  CB  . THR A 1 117 ? 125.560 112.359 115.399 1.00 93.35 ? 105 THR A CB  1 
ATOM   537  O  OG1 . THR A 1 117 ? 124.748 111.721 114.406 1.00 93.35 ? 105 THR A OG1 1 
ATOM   538  C  CG2 . THR A 1 117 ? 124.817 113.534 116.002 1.00 93.35 ? 105 THR A CG2 1 
ATOM   539  N  N   . SER A 1 118 ? 127.425 111.292 112.988 1.00 93.62 ? 106 SER A N   1 
ATOM   540  C  CA  . SER A 1 118 ? 128.046 110.104 112.401 1.00 93.62 ? 106 SER A CA  1 
ATOM   541  C  C   . SER A 1 118 ? 127.515 108.893 113.143 1.00 93.62 ? 106 SER A C   1 
ATOM   542  O  O   . SER A 1 118 ? 128.240 107.924 113.359 1.00 93.62 ? 106 SER A O   1 
ATOM   543  C  CB  . SER A 1 118 ? 129.578 110.162 112.396 1.00 93.62 ? 106 SER A CB  1 
ATOM   544  O  OG  . SER A 1 118 ? 130.127 109.102 111.632 1.00 93.62 ? 106 SER A OG  1 
ATOM   545  N  N   . GLU A 1 119 ? 126.240 108.949 113.531 1.00 93.84 ? 107 GLU A N   1 
ATOM   546  C  CA  . GLU A 1 119 ? 125.641 107.832 114.244 1.00 93.84 ? 107 GLU A CA  1 
ATOM   547  C  C   . GLU A 1 119 ? 124.251 107.487 113.746 1.00 93.84 ? 107 GLU A C   1 
ATOM   548  O  O   . GLU A 1 119 ? 123.627 108.277 113.040 1.00 93.84 ? 107 GLU A O   1 
ATOM   549  C  CB  . GLU A 1 119 ? 125.593 108.108 115.745 1.00 93.84 ? 107 GLU A CB  1 
ATOM   550  C  CG  . GLU A 1 119 ? 126.912 107.892 116.464 1.00 93.84 ? 107 GLU A CG  1 
ATOM   551  C  CD  . GLU A 1 119 ? 127.413 106.463 116.365 1.00 93.84 ? 107 GLU A CD  1 
ATOM   552  O  OE1 . GLU A 1 119 ? 128.643 106.276 116.252 1.00 93.84 ? 107 GLU A OE1 1 
ATOM   553  O  OE2 . GLU A 1 119 ? 126.585 105.528 116.395 1.00 93.84 ? 107 GLU A OE2 1 
ATOM   554  N  N   . GLY A 1 120 ? 123.760 106.312 114.119 1.00 94.55 ? 108 GLY A N   1 
ATOM   555  C  CA  . GLY A 1 120 ? 122.437 105.866 113.715 1.00 94.55 ? 108 GLY A CA  1 
ATOM   556  C  C   . GLY A 1 120 ? 121.391 106.705 114.397 1.00 94.55 ? 108 GLY A C   1 
ATOM   557  O  O   . GLY A 1 120 ? 121.707 107.428 115.333 1.00 94.55 ? 108 GLY A O   1 
ATOM   558  N  N   . GLY A 1 121 ? 120.140 106.617 113.966 1.00 94.64 ? 109 GLY A N   1 
ATOM   559  C  CA  . GLY A 1 121 ? 119.137 107.513 114.513 1.00 94.64 ? 109 GLY A CA  1 
ATOM   560  C  C   . GLY A 1 121 ? 118.949 107.459 116.014 1.00 94.64 ? 109 GLY A C   1 
ATOM   561  O  O   . GLY A 1 121 ? 118.804 108.503 116.639 1.00 94.64 ? 109 GLY A O   1 
ATOM   562  N  N   . ILE A 1 122 ? 119.036 106.288 116.642 1.00 96.95 ? 110 ILE A N   1 
ATOM   563  C  CA  . ILE A 1 122 ? 118.958 106.240 118.112 1.00 96.95 ? 110 ILE A CA  1 
ATOM   564  C  C   . ILE A 1 122 ? 120.173 106.851 118.791 1.00 96.95 ? 110 ILE A C   1 
ATOM   565  O  O   . ILE A 1 122 ? 120.039 107.745 119.625 1.00 96.95 ? 110 ILE A O   1 
ATOM   566  C  CB  . ILE A 1 122 ? 118.837 104.813 118.658 1.00 96.95 ? 110 ILE A CB  1 
ATOM   567  C  CG1 . ILE A 1 122 ? 117.699 104.062 117.987 1.00 96.95 ? 110 ILE A CG1 1 
ATOM   568  C  CG2 . ILE A 1 122 ? 118.596 104.847 120.157 1.00 96.95 ? 110 ILE A CG2 1 
ATOM   569  C  CD1 . ILE A 1 122 ? 117.459 102.710 118.617 1.00 96.95 ? 110 ILE A CD1 1 
ATOM   570  N  N   . THR A 1 123 ? 121.363 106.360 118.465 1.00 95.17 ? 111 THR A N   1 
ATOM   571  C  CA  . THR A 1 123 ? 122.578 106.854 119.113 1.00 95.17 ? 111 THR A CA  1 
ATOM   572  C  C   . THR A 1 123 ? 122.863 108.313 118.791 1.00 95.17 ? 111 THR A C   1 
ATOM   573  O  O   . THR A 1 123 ? 123.586 108.982 119.524 1.00 95.17 ? 111 THR A O   1 
ATOM   574  C  CB  . THR A 1 123 ? 123.798 106.003 118.735 1.00 95.17 ? 111 THR A CB  1 
ATOM   575  O  OG1 . THR A 1 123 ? 123.781 105.748 117.326 1.00 95.17 ? 111 THR A OG1 1 
ATOM   576  C  CG2 . THR A 1 123 ? 123.762 104.679 119.473 1.00 95.17 ? 111 THR A CG2 1 
ATOM   577  N  N   . CYS A 1 124 ? 122.306 108.807 117.693 1.00 96.09 ? 112 CYS A N   1 
ATOM   578  C  CA  . CYS A 1 124 ? 122.502 110.199 117.319 1.00 96.09 ? 112 CYS A CA  1 
ATOM   579  C  C   . CYS A 1 124 ? 121.916 111.127 118.349 1.00 96.09 ? 112 CYS A C   1 
ATOM   580  O  O   . CYS A 1 124 ? 122.536 112.116 118.729 1.00 96.09 ? 112 CYS A O   1 
ATOM   581  C  CB  . CYS A 1 124 ? 121.834 110.473 115.975 1.00 96.09 ? 112 CYS A CB  1 
ATOM   582  S  SG  . CYS A 1 124 ? 121.351 112.186 115.693 1.00 96.09 ? 112 CYS A SG  1 
ATOM   583  N  N   . TRP A 1 125 ? 120.727 110.801 118.831 1.00 97.15 ? 113 TRP A N   1 
ATOM   584  C  CA  . TRP A 1 125 ? 120.068 111.700 119.760 1.00 97.15 ? 113 TRP A CA  1 
ATOM   585  C  C   . TRP A 1 125 ? 120.796 111.821 121.078 1.00 97.15 ? 113 TRP A C   1 
ATOM   586  O  O   . TRP A 1 125 ? 120.766 112.873 121.700 1.00 97.15 ? 113 TRP A O   1 
ATOM   587  C  CB  . TRP A 1 125 ? 118.597 111.337 119.940 1.00 97.15 ? 113 TRP A CB  1 
ATOM   588  C  CG  . TRP A 1 125 ? 117.814 111.825 118.787 1.00 97.15 ? 113 TRP A CG  1 
ATOM   589  C  CD1 . TRP A 1 125 ? 117.203 111.074 117.830 1.00 97.15 ? 113 TRP A CD1 1 
ATOM   590  C  CD2 . TRP A 1 125 ? 117.604 113.192 118.422 1.00 97.15 ? 113 TRP A CD2 1 
ATOM   591  N  NE1 . TRP A 1 125 ? 116.602 111.889 116.904 1.00 97.15 ? 113 TRP A NE1 1 
ATOM   592  C  CE2 . TRP A 1 125 ? 116.834 113.195 117.247 1.00 97.15 ? 113 TRP A CE2 1 
ATOM   593  C  CE3 . TRP A 1 125 ? 117.980 114.415 118.987 1.00 97.15 ? 113 TRP A CE3 1 
ATOM   594  C  CZ2 . TRP A 1 125 ? 116.437 114.370 116.624 1.00 97.15 ? 113 TRP A CZ2 1 
ATOM   595  C  CZ3 . TRP A 1 125 ? 117.584 115.578 118.367 1.00 97.15 ? 113 TRP A CZ3 1 
ATOM   596  C  CH2 . TRP A 1 125 ? 116.820 115.549 117.198 1.00 97.15 ? 113 TRP A CH2 1 
ATOM   597  N  N   . GLU A 1 126 ? 121.473 110.765 121.497 1.00 93.26 ? 114 GLU A N   1 
ATOM   598  C  CA  . GLU A 1 126 ? 122.254 110.851 122.718 1.00 93.26 ? 114 GLU A CA  1 
ATOM   599  C  C   . GLU A 1 126 ? 123.378 111.861 122.547 1.00 93.26 ? 114 GLU A C   1 
ATOM   600  O  O   . GLU A 1 126 ? 123.699 112.595 123.470 1.00 93.26 ? 114 GLU A O   1 
ATOM   601  C  CB  . GLU A 1 126 ? 122.821 109.484 123.086 1.00 93.26 ? 114 GLU A CB  1 
ATOM   602  C  CG  . GLU A 1 126 ? 121.779 108.380 123.107 1.00 93.26 ? 114 GLU A CG  1 
ATOM   603  C  CD  . GLU A 1 126 ? 122.397 107.003 123.223 1.00 93.26 ? 114 GLU A CD  1 
ATOM   604  O  OE1 . GLU A 1 126 ? 121.642 106.008 123.209 1.00 93.26 ? 114 GLU A OE1 1 
ATOM   605  O  OE2 . GLU A 1 126 ? 123.639 106.916 123.323 1.00 93.26 ? 114 GLU A OE2 1 
ATOM   606  N  N   . LYS A 1 127 ? 123.997 111.890 121.376 1.00 91.59 ? 115 LYS A N   1 
ATOM   607  C  CA  . LYS A 1 127 ? 125.040 112.875 121.122 1.00 91.59 ? 115 LYS A CA  1 
ATOM   608  C  C   . LYS A 1 127 ? 124.542 114.317 121.140 1.00 91.59 ? 115 LYS A C   1 
ATOM   609  O  O   . LYS A 1 127 ? 125.222 115.194 121.663 1.00 91.59 ? 115 LYS A O   1 
ATOM   610  C  CB  . LYS A 1 127 ? 125.758 112.583 119.807 1.00 91.59 ? 115 LYS A CB  1 
ATOM   611  C  CG  . LYS A 1 127 ? 126.567 111.300 119.829 1.00 91.59 ? 115 LYS A CG  1 
ATOM   612  C  CD  . LYS A 1 127 ? 127.545 111.248 118.670 1.00 91.59 ? 115 LYS A CD  1 
ATOM   613  C  CE  . LYS A 1 127 ? 128.543 110.119 118.855 1.00 91.59 ? 115 LYS A CE  1 
ATOM   614  N  NZ  . LYS A 1 127 ? 129.272 110.234 120.147 1.00 91.59 ? 115 LYS A NZ  1 
ATOM   615  N  N   . ILE A 1 128 ? 123.369 114.568 120.569 1.00 93.76 ? 116 ILE A N   1 
ATOM   616  C  CA  . ILE A 1 128 ? 122.830 115.930 120.514 1.00 93.76 ? 116 ILE A CA  1 
ATOM   617  C  C   . ILE A 1 128 ? 122.229 116.357 121.844 1.00 93.76 ? 116 ILE A C   1 
ATOM   618  O  O   . ILE A 1 128 ? 122.645 117.357 122.425 1.00 93.76 ? 116 ILE A O   1 
ATOM   619  C  CB  . ILE A 1 128 ? 121.739 116.042 119.435 1.00 93.76 ? 116 ILE A CB  1 
ATOM   620  C  CG1 . ILE A 1 128 ? 122.329 115.781 118.051 1.00 93.76 ? 116 ILE A CG1 1 
ATOM   621  C  CG2 . ILE A 1 128 ? 121.089 117.416 119.464 1.00 93.76 ? 116 ILE A CG2 1 
ATOM   622  C  CD1 . ILE A 1 128 ? 123.349 116.814 117.624 1.00 93.76 ? 116 ILE A CD1 1 
ATOM   623  N  N   . CYS A 1 129 ? 121.254 115.604 122.331 1.00 95.35 ? 117 CYS A N   1 
ATOM   624  C  CA  . CYS A 1 129 ? 120.577 115.920 123.593 1.00 95.35 ? 117 CYS A CA  1 
ATOM   625  C  C   . CYS A 1 129 ? 120.361 114.607 124.360 1.00 95.35 ? 117 CYS A C   1 
ATOM   626  O  O   . CYS A 1 129 ? 119.395 113.899 124.084 1.00 95.35 ? 117 CYS A O   1 
ATOM   627  C  CB  . CYS A 1 129 ? 119.247 116.613 123.367 1.00 95.35 ? 117 CYS A CB  1 
ATOM   628  S  SG  . CYS A 1 129 ? 118.437 117.152 124.888 1.00 95.35 ? 117 CYS A SG  1 
ATOM   629  N  N   . PRO A 1 130 ? 121.255 114.264 125.323 1.00 94.49 ? 118 PRO A N   1 
ATOM   630  C  CA  . PRO A 1 130 ? 121.080 112.956 125.952 1.00 94.49 ? 118 PRO A CA  1 
ATOM   631  C  C   . PRO A 1 130 ? 119.708 112.682 126.573 1.00 94.49 ? 118 PRO A C   1 
ATOM   632  O  O   . PRO A 1 130 ? 119.198 111.580 126.391 1.00 94.49 ? 118 PRO A O   1 
ATOM   633  C  CB  . PRO A 1 130 ? 122.167 112.961 127.020 1.00 94.49 ? 118 PRO A CB  1 
ATOM   634  C  CG  . PRO A 1 130 ? 123.251 113.784 126.424 1.00 94.49 ? 118 PRO A CG  1 
ATOM   635  C  CD  . PRO A 1 130 ? 122.548 114.875 125.664 1.00 94.49 ? 118 PRO A CD  1 
ATOM   636  N  N   . LEU A 1 131 ? 119.137 113.638 127.296 1.00 96.73 ? 119 LEU A N   1 
ATOM   637  C  CA  . LEU A 1 131 ? 117.853 113.421 127.965 1.00 96.73 ? 119 LEU A CA  1 
ATOM   638  C  C   . LEU A 1 131 ? 116.790 112.983 126.972 1.00 96.73 ? 119 LEU A C   1 
ATOM   639  O  O   . LEU A 1 131 ? 116.061 112.023 127.214 1.00 96.73 ? 119 LEU A O   1 
ATOM   640  C  CB  . LEU A 1 131 ? 117.405 114.689 128.698 1.00 96.73 ? 119 LEU A CB  1 
ATOM   641  C  CG  . LEU A 1 131 ? 116.099 114.639 129.494 1.00 96.73 ? 119 LEU A CG  1 
ATOM   642  C  CD1 . LEU A 1 131 ? 116.157 113.570 130.573 1.00 96.73 ? 119 LEU A CD1 1 
ATOM   643  C  CD2 . LEU A 1 131 ? 115.799 115.996 130.107 1.00 96.73 ? 119 LEU A CD2 1 
ATOM   644  N  N   . PHE A 1 132 ? 116.690 113.690 125.855 1.00 97.70 ? 120 PHE A N   1 
ATOM   645  C  CA  . PHE A 1 132 ? 115.719 113.329 124.836 1.00 97.70 ? 120 PHE A CA  1 
ATOM   646  C  C   . PHE A 1 132 ? 116.283 112.288 123.892 1.00 97.70 ? 120 PHE A C   1 
ATOM   647  O  O   . PHE A 1 132 ? 116.476 112.570 122.711 1.00 97.70 ? 120 PHE A O   1 
ATOM   648  C  CB  . PHE A 1 132 ? 115.331 114.558 124.018 1.00 97.70 ? 120 PHE A CB  1 
ATOM   649  C  CG  . PHE A 1 132 ? 114.409 115.507 124.728 1.00 97.70 ? 120 PHE A CG  1 
ATOM   650  C  CD1 . PHE A 1 132 ? 114.890 116.381 125.687 1.00 97.70 ? 120 PHE A CD1 1 
ATOM   651  C  CD2 . PHE A 1 132 ? 113.064 115.549 124.407 1.00 97.70 ? 120 PHE A CD2 1 
ATOM   652  C  CE1 . PHE A 1 132 ? 114.045 117.262 126.330 1.00 97.70 ? 120 PHE A CE1 1 
ATOM   653  C  CE2 . PHE A 1 132 ? 112.214 116.431 125.043 1.00 97.70 ? 120 PHE A CE2 1 
ATOM   654  C  CZ  . PHE A 1 132 ? 112.704 117.287 126.007 1.00 97.70 ? 120 PHE A CZ  1 
ATOM   655  N  N   . SER A 1 133 ? 116.542 111.084 124.384 1.00 96.95 ? 121 SER A N   1 
ATOM   656  C  CA  . SER A 1 133 ? 116.991 110.021 123.499 1.00 96.95 ? 121 SER A CA  1 
ATOM   657  C  C   . SER A 1 133 ? 115.733 109.268 123.169 1.00 96.95 ? 121 SER A C   1 
ATOM   658  O  O   . SER A 1 133 ? 115.741 108.365 122.338 1.00 96.95 ? 121 SER A O   1 
ATOM   659  C  CB  . SER A 1 133 ? 118.016 109.122 124.182 1.00 96.95 ? 121 SER A CB  1 
ATOM   660  O  OG  . SER A 1 133 ? 117.547 108.675 125.440 1.00 96.95 ? 121 SER A OG  1 
ATOM   661  N  N   . GLY A 1 134 ? 114.642 109.647 123.820 1.00 98.20 ? 122 GLY A N   1 
ATOM   662  C  CA  . GLY A 1 134 ? 113.361 109.022 123.562 1.00 98.20 ? 122 GLY A CA  1 
ATOM   663  C  C   . GLY A 1 134 ? 113.006 109.135 122.109 1.00 98.20 ? 122 GLY A C   1 
ATOM   664  O  O   . GLY A 1 134 ? 112.364 108.251 121.565 1.00 98.20 ? 122 GLY A O   1 
ATOM   665  N  N   . ILE A 1 135 ? 113.411 110.226 121.474 1.00 98.48 ? 123 ILE A N   1 
ATOM   666  C  CA  . ILE A 1 135 ? 113.068 110.451 120.083 1.00 98.48 ? 123 ILE A CA  1 
ATOM   667  C  C   . ILE A 1 135 ? 113.610 109.315 119.226 1.00 98.48 ? 123 ILE A C   1 
ATOM   668  O  O   . ILE A 1 135 ? 112.914 108.820 118.345 1.00 98.48 ? 123 ILE A O   1 
ATOM   669  C  CB  . ILE A 1 135 ? 113.681 111.783 119.609 1.00 98.48 ? 123 ILE A CB  1 
ATOM   670  C  CG1 . ILE A 1 135 ? 113.245 112.923 120.528 1.00 98.48 ? 123 ILE A CG1 1 
ATOM   671  C  CG2 . ILE A 1 135 ? 113.315 112.087 118.167 1.00 98.48 ? 123 ILE A CG2 1 
ATOM   672  C  CD1 . ILE A 1 135 ? 113.948 114.228 120.245 1.00 98.48 ? 123 ILE A CD1 1 
ATOM   673  N  N   . GLY A 1 136 ? 114.834 108.874 119.491 1.00 98.22 ? 124 GLY A N   1 
ATOM   674  C  CA  . GLY A 1 136 ? 115.379 107.755 118.748 1.00 98.22 ? 124 GLY A CA  1 
ATOM   675  C  C   . GLY A 1 136 ? 114.623 106.456 118.948 1.00 98.22 ? 124 GLY A C   1 
ATOM   676  O  O   . GLY A 1 136 ? 114.339 105.748 117.987 1.00 98.22 ? 124 GLY A O   1 
ATOM   677  N  N   . TYR A 1 137 ? 114.272 106.138 120.188 1.00 98.34 ? 125 TYR A N   1 
ATOM   678  C  CA  . TYR A 1 137 ? 113.495 104.931 120.458 1.00 98.34 ? 125 TYR A CA  1 
ATOM   679  C  C   . TYR A 1 137 ? 112.119 105.029 119.830 1.00 98.34 ? 125 TYR A C   1 
ATOM   680  O  O   . TYR A 1 137 ? 111.603 104.050 119.298 1.00 98.34 ? 125 TYR A O   1 
ATOM   681  C  CB  . TYR A 1 137 ? 113.402 104.651 121.957 1.00 98.34 ? 125 TYR A CB  1 
ATOM   682  C  CG  . TYR A 1 137 ? 114.746 104.425 122.601 1.00 98.34 ? 125 TYR A CG  1 
ATOM   683  C  CD1 . TYR A 1 137 ? 115.513 103.319 122.273 1.00 98.34 ? 125 TYR A CD1 1 
ATOM   684  C  CD2 . TYR A 1 137 ? 115.247 105.315 123.537 1.00 98.34 ? 125 TYR A CD2 1 
ATOM   685  C  CE1 . TYR A 1 137 ? 116.746 103.107 122.857 1.00 98.34 ? 125 TYR A CE1 1 
ATOM   686  C  CE2 . TYR A 1 137 ? 116.480 105.114 124.126 1.00 98.34 ? 125 TYR A CE2 1 
ATOM   687  C  CZ  . TYR A 1 137 ? 117.225 104.008 123.782 1.00 98.34 ? 125 TYR A CZ  1 
ATOM   688  O  OH  . TYR A 1 137 ? 118.452 103.798 124.365 1.00 98.34 ? 125 TYR A OH  1 
ATOM   689  N  N   . ALA A 1 138 ? 111.503 106.200 119.903 1.00 98.43 ? 126 ALA A N   1 
ATOM   690  C  CA  . ALA A 1 138 ? 110.173 106.375 119.347 1.00 98.43 ? 126 ALA A CA  1 
ATOM   691  C  C   . ALA A 1 138 ? 110.221 106.091 117.871 1.00 98.43 ? 126 ALA A C   1 
ATOM   692  O  O   . ALA A 1 138 ? 109.298 105.499 117.318 1.00 98.43 ? 126 ALA A O   1 
ATOM   693  C  CB  . ALA A 1 138 ? 109.682 107.783 119.589 1.00 98.43 ? 126 ALA A CB  1 
ATOM   694  N  N   . SER A 1 139 ? 111.302 106.507 117.225 1.00 97.75 ? 127 SER A N   1 
ATOM   695  C  CA  . SER A 1 139 ? 111.434 106.296 115.793 1.00 97.75 ? 127 SER A CA  1 
ATOM   696  C  C   . SER A 1 139 ? 111.476 104.815 115.452 1.00 97.75 ? 127 SER A C   1 
ATOM   697  O  O   . SER A 1 139 ? 110.852 104.391 114.497 1.00 97.75 ? 127 SER A O   1 
ATOM   698  C  CB  . SER A 1 139 ? 112.664 107.009 115.239 1.00 97.75 ? 127 SER A CB  1 
ATOM   699  O  OG  . SER A 1 139 ? 113.826 106.211 115.362 1.00 97.75 ? 127 SER A OG  1 
ATOM   700  N  N   . VAL A 1 140 ? 112.182 104.021 116.247 1.00 98.07 ? 128 VAL A N   1 
ATOM   701  C  CA  . VAL A 1 140 ? 112.260 102.585 115.994 1.00 98.07 ? 128 VAL A CA  1 
ATOM   702  C  C   . VAL A 1 140 ? 110.896 101.910 116.090 1.00 98.07 ? 128 VAL A C   1 
ATOM   703  O  O   . VAL A 1 140 ? 110.559 101.064 115.263 1.00 98.07 ? 128 VAL A O   1 
ATOM   704  C  CB  . VAL A 1 140 ? 113.314 101.903 116.890 1.00 98.07 ? 128 VAL A CB  1 
ATOM   705  C  CG1 . VAL A 1 140 ? 113.315 100.392 116.719 1.00 98.07 ? 128 VAL A CG1 1 
ATOM   706  C  CG2 . VAL A 1 140 ? 114.684 102.476 116.584 1.00 98.07 ? 128 VAL A CG2 1 
ATOM   707  N  N   . VAL A 1 141 ? 110.136 102.216 117.131 1.00 98.02 ? 129 VAL A N   1 
ATOM   708  C  CA  . VAL A 1 141 ? 108.830 101.601 117.290 1.00 98.02 ? 129 VAL A CA  1 
ATOM   709  C  C   . VAL A 1 141 ? 108.009 101.953 116.072 1.00 98.02 ? 129 VAL A C   1 
ATOM   710  O  O   . VAL A 1 141 ? 107.315 101.109 115.518 1.00 98.02 ? 129 VAL A O   1 
ATOM   711  C  CB  . VAL A 1 141 ? 108.125 102.090 118.563 1.00 98.02 ? 129 VAL A CB  1 
ATOM   712  C  CG1 . VAL A 1 141 ? 106.757 101.443 118.704 1.00 98.02 ? 129 VAL A CG1 1 
ATOM   713  C  CG2 . VAL A 1 141 ? 108.983 101.782 119.777 1.00 98.02 ? 129 VAL A CG2 1 
ATOM   714  N  N   . ILE A 1 142 ? 108.110 103.197 115.633 1.00 97.37 ? 130 ILE A N   1 
ATOM   715  C  CA  . ILE A 1 142 ? 107.354 103.645 114.471 1.00 97.37 ? 130 ILE A CA  1 
ATOM   716  C  C   . ILE A 1 142 ? 107.753 102.904 113.186 1.00 97.37 ? 130 ILE A C   1 
ATOM   717  O  O   . ILE A 1 142 ? 106.885 102.537 112.398 1.00 97.37 ? 130 ILE A O   1 
ATOM   718  C  CB  . ILE A 1 142 ? 107.450 105.174 114.324 1.00 97.37 ? 130 ILE A CB  1 
ATOM   719  C  CG1 . ILE A 1 142 ? 106.804 105.860 115.518 1.00 97.37 ? 130 ILE A CG1 1 
ATOM   720  C  CG2 . ILE A 1 142 ? 106.696 105.660 113.121 1.00 97.37 ? 130 ILE A CG2 1 
ATOM   721  C  CD1 . ILE A 1 142 ? 106.709 107.359 115.363 1.00 97.37 ? 130 ILE A CD1 1 
ATOM   722  N  N   . VAL A 1 143 ? 109.045 102.653 112.978 1.00 97.25 ? 131 VAL A N   1 
ATOM   723  C  CA  . VAL A 1 143 ? 109.476 101.890 111.804 1.00 97.25 ? 131 VAL A CA  1 
ATOM   724  C  C   . VAL A 1 143 ? 108.925 100.489 111.861 1.00 97.25 ? 131 VAL A C   1 
ATOM   725  O  O   . VAL A 1 143 ? 108.377 100.002 110.885 1.00 97.25 ? 131 VAL A O   1 
ATOM   726  C  CB  . VAL A 1 143 ? 111.000 101.717 111.727 1.00 97.25 ? 131 VAL A CB  1 
ATOM   727  C  CG1 . VAL A 1 143 ? 111.398 101.075 110.409 1.00 97.25 ? 131 VAL A CG1 1 
ATOM   728  C  CG2 . VAL A 1 143 ? 111.696 103.040 111.867 1.00 97.25 ? 131 VAL A CG2 1 
ATOM   729  N  N   . SER A 1 144 ? 109.080 99.827  112.998 1.00 97.66 ? 132 SER A N   1 
ATOM   730  C  CA  . SER A 1 144 ? 108.645 98.445  113.122 1.00 97.66 ? 132 SER A CA  1 
ATOM   731  C  C   . SER A 1 144 ? 107.195 98.302  112.711 1.00 97.66 ? 132 SER A C   1 
ATOM   732  O  O   . SER A 1 144 ? 106.844 97.395  111.958 1.00 97.66 ? 132 SER A O   1 
ATOM   733  C  CB  . SER A 1 144 ? 108.819 97.971  114.560 1.00 97.66 ? 132 SER A CB  1 
ATOM   734  O  OG  . SER A 1 144 ? 110.149 98.171  115.000 1.00 97.66 ? 132 SER A OG  1 
ATOM   735  N  N   . LEU A 1 145 ? 106.349 99.209  113.176 1.00 97.37 ? 133 LEU A N   1 
ATOM   736  C  CA  . LEU A 1 145 ? 104.951 99.176  112.788 1.00 97.37 ? 133 LEU A CA  1 
ATOM   737  C  C   . LEU A 1 145 ? 104.793 99.452  111.302 1.00 97.37 ? 133 LEU A C   1 
ATOM   738  O  O   . LEU A 1 145 ? 103.987 98.810  110.629 1.00 97.37 ? 133 LEU A O   1 
ATOM   739  C  CB  . LEU A 1 145 ? 104.142 100.157 113.627 1.00 97.37 ? 133 LEU A CB  1 
ATOM   740  C  CG  . LEU A 1 145 ? 104.162 99.847  115.125 1.00 97.37 ? 133 LEU A CG  1 
ATOM   741  C  CD1 . LEU A 1 145 ? 103.589 100.985 115.954 1.00 97.37 ? 133 LEU A CD1 1 
ATOM   742  C  CD2 . LEU A 1 145 ? 103.448 98.539  115.422 1.00 97.37 ? 133 LEU A CD2 1 
ATOM   743  N  N   . LEU A 1 146 ? 105.567 100.398 110.782 1.00 96.54 ? 134 LEU A N   1 
ATOM   744  C  CA  . LEU A 1 146 ? 105.488 100.727 109.365 1.00 96.54 ? 134 LEU A CA  1 
ATOM   745  C  C   . LEU A 1 146 ? 105.893 99.548  108.517 1.00 96.54 ? 134 LEU A C   1 
ATOM   746  O  O   . LEU A 1 146 ? 105.245 99.248  107.531 1.00 96.54 ? 134 LEU A O   1 
ATOM   747  C  CB  . LEU A 1 146 ? 106.377 101.917 109.025 1.00 96.54 ? 134 LEU A CB  1 
ATOM   748  C  CG  . LEU A 1 146 ? 106.449 102.330 107.558 1.00 96.54 ? 134 LEU A CG  1 
ATOM   749  C  CD1 . LEU A 1 146 ? 105.077 102.773 107.092 1.00 96.54 ? 134 LEU A CD1 1 
ATOM   750  C  CD2 . LEU A 1 146 ? 107.470 103.439 107.358 1.00 96.54 ? 134 LEU A CD2 1 
ATOM   751  N  N   . ASN A 1 147 ? 106.979 98.884  108.887 1.00 97.91 ? 135 ASN A N   1 
ATOM   752  C  CA  . ASN A 1 147 ? 107.464 97.758  108.105 1.00 97.91 ? 135 ASN A CA  1 
ATOM   753  C  C   . ASN A 1 147 ? 106.392 96.696  107.968 1.00 97.91 ? 135 ASN A C   1 
ATOM   754  O  O   . ASN A 1 147 ? 106.209 96.135  106.893 1.00 97.91 ? 135 ASN A O   1 
ATOM   755  C  CB  . ASN A 1 147 ? 108.732 97.173  108.714 1.00 97.91 ? 135 ASN A CB  1 
ATOM   756  C  CG  . ASN A 1 147 ? 109.946 98.034  108.450 1.00 97.91 ? 135 ASN A CG  1 
ATOM   757  O  OD1 . ASN A 1 147 ? 109.904 98.944  107.624 1.00 97.91 ? 135 ASN A OD1 1 
ATOM   758  N  ND2 . ASN A 1 147 ? 111.035 97.752  109.146 1.00 97.91 ? 135 ASN A ND2 1 
ATOM   759  N  N   . VAL A 1 148 ? 105.671 96.434  109.052 1.00 97.48 ? 136 VAL A N   1 
ATOM   760  C  CA  . VAL A 1 148 ? 104.619 95.428  109.026 1.00 97.48 ? 136 VAL A CA  1 
ATOM   761  C  C   . VAL A 1 148 ? 103.534 95.780  108.013 1.00 97.48 ? 136 VAL A C   1 
ATOM   762  O  O   . VAL A 1 148 ? 103.256 95.006  107.110 1.00 97.48 ? 136 VAL A O   1 
ATOM   763  C  CB  . VAL A 1 148 ? 103.997 95.214  110.421 1.00 97.48 ? 136 VAL A CB  1 
ATOM   764  C  CG1 . VAL A 1 148 ? 102.840 94.231  110.355 1.00 97.48 ? 136 VAL A CG1 1 
ATOM   765  C  CG2 . VAL A 1 148 ? 105.047 94.714  111.396 1.00 97.48 ? 136 VAL A CG2 1 
ATOM   766  N  N   . TYR A 1 149 ? 102.902 96.935  108.165 1.00 95.88 ? 137 TYR A N   1 
ATOM   767  C  CA  . TYR A 1 149 ? 101.892 97.320  107.192 1.00 95.88 ? 137 TYR A CA  1 
ATOM   768  C  C   . TYR A 1 149 ? 102.367 97.614  105.764 1.00 95.88 ? 137 TYR A C   1 
ATOM   769  O  O   . TYR A 1 149 ? 101.699 97.234  104.812 1.00 95.88 ? 137 TYR A O   1 
ATOM   770  C  CB  . TYR A 1 149 ? 100.858 98.321  107.749 1.00 95.88 ? 137 TYR A CB  1 
ATOM   771  C  CG  . TYR A 1 149 ? 101.201 99.788  107.797 1.00 95.88 ? 137 TYR A CG  1 
ATOM   772  C  CD1 . TYR A 1 149 ? 101.039 100.598 106.682 1.00 95.88 ? 137 TYR A CD1 1 
ATOM   773  C  CD2 . TYR A 1 149 ? 101.596 100.382 108.982 1.00 95.88 ? 137 TYR A CD2 1 
ATOM   774  C  CE1 . TYR A 1 149 ? 101.319 101.946 106.732 1.00 95.88 ? 137 TYR A CE1 1 
ATOM   775  C  CE2 . TYR A 1 149 ? 101.877 101.729 109.042 1.00 95.88 ? 137 TYR A CE2 1 
ATOM   776  C  CZ  . TYR A 1 149 ? 101.732 102.507 107.916 1.00 95.88 ? 137 TYR A CZ  1 
ATOM   777  O  OH  . TYR A 1 149 ? 102.011 103.853 107.972 1.00 95.88 ? 137 TYR A OH  1 
ATOM   778  N  N   . TYR A 1 150 ? 103.513 98.263  105.609 1.00 95.74 ? 138 TYR A N   1 
ATOM   779  C  CA  . TYR A 1 150 ? 104.003 98.625  104.280 1.00 95.74 ? 138 TYR A CA  1 
ATOM   780  C  C   . TYR A 1 150 ? 104.205 97.408  103.393 1.00 95.74 ? 138 TYR A C   1 
ATOM   781  O  O   . TYR A 1 150 ? 103.905 97.451  102.203 1.00 95.74 ? 138 TYR A O   1 
ATOM   782  C  CB  . TYR A 1 150 ? 105.306 99.415  104.387 1.00 95.74 ? 138 TYR A CB  1 
ATOM   783  C  CG  . TYR A 1 150 ? 105.694 100.182 103.145 1.00 95.74 ? 138 TYR A CG  1 
ATOM   784  C  CD1 . TYR A 1 150 ? 105.121 101.412 102.858 1.00 95.74 ? 138 TYR A CD1 1 
ATOM   785  C  CD2 . TYR A 1 150 ? 106.651 99.688  102.273 1.00 95.74 ? 138 TYR A CD2 1 
ATOM   786  C  CE1 . TYR A 1 150 ? 105.481 102.120 101.728 1.00 95.74 ? 138 TYR A CE1 1 
ATOM   787  C  CE2 . TYR A 1 150 ? 107.016 100.386 101.142 1.00 95.74 ? 138 TYR A CE2 1 
ATOM   788  C  CZ  . TYR A 1 150 ? 106.429 101.601 100.874 1.00 95.74 ? 138 TYR A CZ  1 
ATOM   789  O  OH  . TYR A 1 150 ? 106.796 102.297 99.747  1.00 95.74 ? 138 TYR A OH  1 
ATOM   790  N  N   . ILE A 1 151 ? 104.716 96.323  103.959 1.00 97.88 ? 139 ILE A N   1 
ATOM   791  C  CA  . ILE A 1 151 ? 104.966 95.122  103.185 1.00 97.88 ? 139 ILE A CA  1 
ATOM   792  C  C   . ILE A 1 151 ? 103.669 94.461  102.691 1.00 97.88 ? 139 ILE A C   1 
ATOM   793  O  O   . ILE A 1 151 ? 103.704 93.690  101.735 1.00 97.88 ? 139 ILE A O   1 
ATOM   794  C  CB  . ILE A 1 151 ? 105.789 94.116  104.001 1.00 97.88 ? 139 ILE A CB  1 
ATOM   795  C  CG1 . ILE A 1 151 ? 106.491 93.101  103.096 1.00 97.88 ? 139 ILE A CG1 1 
ATOM   796  C  CG2 . ILE A 1 151 ? 104.913 93.440  105.040 1.00 97.88 ? 139 ILE A CG2 1 
ATOM   797  C  CD1 . ILE A 1 151 ? 107.820 93.581  102.566 1.00 97.88 ? 139 ILE A CD1 1 
ATOM   798  N  N   . VAL A 1 152 ? 102.524 94.766  103.302 1.00 97.84 ? 140 VAL A N   1 
ATOM   799  C  CA  . VAL A 1 152 ? 101.287 94.176  102.801 1.00 97.84 ? 140 VAL A CA  1 
ATOM   800  C  C   . VAL A 1 152 ? 100.775 94.889  101.558 1.00 97.84 ? 140 VAL A C   1 
ATOM   801  O  O   . VAL A 1 152 ? 100.114 94.267  100.730 1.00 97.84 ? 140 VAL A O   1 
ATOM   802  C  CB  . VAL A 1 152 ? 100.197 94.033  103.879 1.00 97.84 ? 140 VAL A CB  1 
ATOM   803  C  CG1 . VAL A 1 152 ? 98.895  93.532  103.289 1.00 97.84 ? 140 VAL A CG1 1 
ATOM   804  C  CG2 . VAL A 1 152 ? 100.667 93.090  104.973 1.00 97.84 ? 140 VAL A CG2 1 
ATOM   805  N  N   . ILE A 1 153 ? 101.074 96.176  101.396 1.00 95.74 ? 141 ILE A N   1 
ATOM   806  C  CA  . ILE A 1 153 ? 100.692 96.837  100.152 1.00 95.74 ? 141 ILE A CA  1 
ATOM   807  C  C   . ILE A 1 153 ? 101.460 96.171  99.025  1.00 95.74 ? 141 ILE A C   1 
ATOM   808  O  O   . ILE A 1 153 ? 100.907 95.900  97.959  1.00 95.74 ? 141 ILE A O   1 
ATOM   809  C  CB  . ILE A 1 153 ? 101.048 98.329  100.143 1.00 95.74 ? 141 ILE A CB  1 
ATOM   810  C  CG1 . ILE A 1 153 ? 100.251 99.088  101.194 1.00 95.74 ? 141 ILE A CG1 1 
ATOM   811  C  CG2 . ILE A 1 153 ? 100.828 98.922  98.760  1.00 95.74 ? 141 ILE A CG2 1 
ATOM   812  C  CD1 . ILE A 1 153 ? 101.033 99.362  102.457 1.00 95.74 ? 141 ILE A CD1 1 
ATOM   813  N  N   . LEU A 1 154 ? 102.733 95.882  99.264  1.00 97.83 ? 142 LEU A N   1 
ATOM   814  C  CA  . LEU A 1 154 ? 103.541 95.199  98.263  1.00 97.83 ? 142 LEU A CA  1 
ATOM   815  C  C   . LEU A 1 154 ? 102.992 93.810  97.977  1.00 97.83 ? 142 LEU A C   1 
ATOM   816  O  O   . LEU A 1 154 ? 103.009 93.363  96.839  1.00 97.83 ? 142 LEU A O   1 
ATOM   817  C  CB  . LEU A 1 154 ? 104.995 95.121  98.714  1.00 97.83 ? 142 LEU A CB  1 
ATOM   818  C  CG  . LEU A 1 154 ? 105.757 96.436  98.640  1.00 97.83 ? 142 LEU A CG  1 
ATOM   819  C  CD1 . LEU A 1 154 ? 107.037 96.368  99.455  1.00 97.83 ? 142 LEU A CD1 1 
ATOM   820  C  CD2 . LEU A 1 154 ? 106.047 96.738  97.182  1.00 97.83 ? 142 LEU A CD2 1 
ATOM   821  N  N   . ALA A 1 155 ? 102.520 93.119  99.008  1.00 98.50 ? 143 ALA A N   1 
ATOM   822  C  CA  . ALA A 1 155 ? 101.959 91.783  98.833  1.00 98.50 ? 143 ALA A CA  1 
ATOM   823  C  C   . ALA A 1 155 ? 100.725 91.783  97.941  1.00 98.50 ? 143 ALA A C   1 
ATOM   824  O  O   . ALA A 1 155 ? 100.550 90.874  97.139  1.00 98.50 ? 143 ALA A O   1 
ATOM   825  C  CB  . ALA A 1 155 ? 101.648 91.153  100.176 1.00 98.50 ? 143 ALA A CB  1 
ATOM   826  N  N   . TRP A 1 156 ? 99.860  92.782  98.065  1.00 98.00 ? 144 TRP A N   1 
ATOM   827  C  CA  . TRP A 1 156 ? 98.704  92.852  97.181  1.00 98.00 ? 144 TRP A CA  1 
ATOM   828  C  C   . TRP A 1 156 ? 99.172  92.984  95.753  1.00 98.00 ? 144 TRP A C   1 
ATOM   829  O  O   . TRP A 1 156 ? 98.603  92.379  94.854  1.00 98.00 ? 144 TRP A O   1 
ATOM   830  C  CB  . TRP A 1 156 ? 97.811  94.032  97.514  1.00 98.00 ? 144 TRP A CB  1 
ATOM   831  C  CG  . TRP A 1 156 ? 97.235  93.989  98.864  1.00 98.00 ? 144 TRP A CG  1 
ATOM   832  C  CD1 . TRP A 1 156 ? 96.848  92.887  99.554  1.00 98.00 ? 144 TRP A CD1 1 
ATOM   833  C  CD2 . TRP A 1 156 ? 96.956  95.107  99.699  1.00 98.00 ? 144 TRP A CD2 1 
ATOM   834  N  NE1 . TRP A 1 156 ? 96.353  93.245  100.781 1.00 98.00 ? 144 TRP A NE1 1 
ATOM   835  C  CE2 . TRP A 1 156 ? 96.407  94.608  100.892 1.00 98.00 ? 144 TRP A CE2 1 
ATOM   836  C  CE3 . TRP A 1 156 ? 97.119  96.485  99.555  1.00 98.00 ? 144 TRP A CE3 1 
ATOM   837  C  CZ2 . TRP A 1 156 ? 96.022  95.434  101.931 1.00 98.00 ? 144 TRP A CZ2 1 
ATOM   838  C  CZ3 . TRP A 1 156 ? 96.740  97.300  100.585 1.00 98.00 ? 144 TRP A CZ3 1 
ATOM   839  C  CH2 . TRP A 1 156 ? 96.201  96.774  101.758 1.00 98.00 ? 144 TRP A CH2 1 
ATOM   840  N  N   . ALA A 1 157 ? 100.207 93.784  95.538  1.00 97.45 ? 145 ALA A N   1 
ATOM   841  C  CA  . ALA A 1 157 ? 100.749 93.956  94.198  1.00 97.45 ? 145 ALA A CA  1 
ATOM   842  C  C   . ALA A 1 157 ? 101.319 92.653  93.653  1.00 97.45 ? 145 ALA A C   1 
ATOM   843  O  O   . ALA A 1 157 ? 101.200 92.380  92.466  1.00 97.45 ? 145 ALA A O   1 
ATOM   844  C  CB  . ALA A 1 157 ? 101.786 95.061  94.172  1.00 97.45 ? 145 ALA A CB  1 
ATOM   845  N  N   . THR A 1 158 ? 101.959 91.858  94.506  1.00 98.50 ? 146 THR A N   1 
ATOM   846  C  CA  . THR A 1 158 ? 102.485 90.567  94.076  1.00 98.50 ? 146 THR A CA  1 
ATOM   847  C  C   . THR A 1 158 ? 101.345 89.675  93.632  1.00 98.50 ? 146 THR A C   1 
ATOM   848  O  O   . THR A 1 158 ? 101.447 88.989  92.619  1.00 98.50 ? 146 THR A O   1 
ATOM   849  C  CB  . THR A 1 158 ? 103.241 89.863  95.211  1.00 98.50 ? 146 THR A CB  1 
ATOM   850  O  OG1 . THR A 1 158 ? 104.045 90.817  95.915  1.00 98.50 ? 146 THR A OG1 1 
ATOM   851  C  CG2 . THR A 1 158 ? 104.134 88.768  94.665  1.00 98.50 ? 146 THR A CG2 1 
ATOM   852  N  N   . TYR A 1 159 ? 100.247 89.693  94.374  1.00 98.43 ? 147 TYR A N   1 
ATOM   853  C  CA  . TYR A 1 159 ? 99.083  88.908  93.993  1.00 98.43 ? 147 TYR A CA  1 
ATOM   854  C  C   . TYR A 1 159 ? 98.581  89.397  92.654  1.00 98.43 ? 147 TYR A C   1 
ATOM   855  O  O   . TYR A 1 159 ? 98.241  88.601  91.782  1.00 98.43 ? 147 TYR A O   1 
ATOM   856  C  CB  . TYR A 1 159 ? 97.984  89.040  95.041  1.00 98.43 ? 147 TYR A CB  1 
ATOM   857  C  CG  . TYR A 1 159 ? 96.792  88.161  94.785  1.00 98.43 ? 147 TYR A CG  1 
ATOM   858  C  CD1 . TYR A 1 159 ? 96.764  86.855  95.243  1.00 98.43 ? 147 TYR A CD1 1 
ATOM   859  C  CD2 . TYR A 1 159 ? 95.695  88.634  94.083  1.00 98.43 ? 147 TYR A CD2 1 
ATOM   860  C  CE1 . TYR A 1 159 ? 95.675  86.043  95.008  1.00 98.43 ? 147 TYR A CE1 1 
ATOM   861  C  CE2 . TYR A 1 159 ? 94.607  87.829  93.840  1.00 98.43 ? 147 TYR A CE2 1 
ATOM   862  C  CZ  . TYR A 1 159 ? 94.599  86.536  94.309  1.00 98.43 ? 147 TYR A CZ  1 
ATOM   863  O  OH  . TYR A 1 159 ? 93.513  85.728  94.074  1.00 98.43 ? 147 TYR A OH  1 
ATOM   864  N  N   . TYR A 1 160 ? 98.548  90.710  92.477  1.00 98.17 ? 148 TYR A N   1 
ATOM   865  C  CA  . TYR A 1 160 ? 98.062  91.284  91.231  1.00 98.17 ? 148 TYR A CA  1 
ATOM   866  C  C   . TYR A 1 160 ? 98.926  90.865  90.061  1.00 98.17 ? 148 TYR A C   1 
ATOM   867  O  O   . TYR A 1 160 ? 98.414  90.585  88.988  1.00 98.17 ? 148 TYR A O   1 
ATOM   868  C  CB  . TYR A 1 160 ? 98.052  92.804  91.324  1.00 98.17 ? 148 TYR A CB  1 
ATOM   869  C  CG  . TYR A 1 160 ? 96.716  93.418  91.656  1.00 98.17 ? 148 TYR A CG  1 
ATOM   870  C  CD1 . TYR A 1 160 ? 95.753  93.588  90.677  1.00 98.17 ? 148 TYR A CD1 1 
ATOM   871  C  CD2 . TYR A 1 160 ? 96.427  93.855  92.939  1.00 98.17 ? 148 TYR A CD2 1 
ATOM   872  C  CE1 . TYR A 1 160 ? 94.534  94.161  90.966  1.00 98.17 ? 148 TYR A CE1 1 
ATOM   873  C  CE2 . TYR A 1 160 ? 95.208  94.428  93.238  1.00 98.17 ? 148 TYR A CE2 1 
ATOM   874  C  CZ  . TYR A 1 160 ? 94.266  94.576  92.245  1.00 98.17 ? 148 TYR A CZ  1 
ATOM   875  O  OH  . TYR A 1 160 ? 93.048  95.143  92.525  1.00 98.17 ? 148 TYR A OH  1 
ATOM   876  N  N   . LEU A 1 161 ? 100.238 90.826  90.260  1.00 97.95 ? 149 LEU A N   1 
ATOM   877  C  CA  . LEU A 1 161 ? 101.152 90.456  89.189  1.00 97.95 ? 149 LEU A CA  1 
ATOM   878  C  C   . LEU A 1 161 ? 100.884 89.036  88.728  1.00 97.95 ? 149 LEU A C   1 
ATOM   879  O  O   . LEU A 1 161 ? 100.846 88.764  87.529  1.00 97.95 ? 149 LEU A O   1 
ATOM   880  C  CB  . LEU A 1 161 ? 102.591 90.560  89.686  1.00 97.95 ? 149 LEU A CB  1 
ATOM   881  C  CG  . LEU A 1 161 ? 103.712 90.481  88.658  1.00 97.95 ? 149 LEU A CG  1 
ATOM   882  C  CD1 . LEU A 1 161 ? 103.671 91.722  87.786  1.00 97.95 ? 149 LEU A CD1 1 
ATOM   883  C  CD2 . LEU A 1 161 ? 105.053 90.377  89.364  1.00 97.95 ? 149 LEU A CD2 1 
ATOM   884  N  N   . PHE A 1 162 ? 100.673 88.128  89.675  1.00 98.26 ? 150 PHE A N   1 
ATOM   885  C  CA  . PHE A 1 162 ? 100.379 86.744  89.327  1.00 98.26 ? 150 PHE A CA  1 
ATOM   886  C  C   . PHE A 1 162 ? 99.069  86.667  88.575  1.00 98.26 ? 150 PHE A C   1 
ATOM   887  O  O   . PHE A 1 162 ? 98.951  85.923  87.605  1.00 98.26 ? 150 PHE A O   1 
ATOM   888  C  CB  . PHE A 1 162 ? 100.348 85.872  90.576  1.00 98.26 ? 150 PHE A CB  1 
ATOM   889  C  CG  . PHE A 1 162 ? 101.680 85.749  91.253  1.00 98.26 ? 150 PHE A CG  1 
ATOM   890  C  CD1 . PHE A 1 162 ? 102.849 85.750  90.510  1.00 98.26 ? 150 PHE A CD1 1 
ATOM   891  C  CD2 . PHE A 1 162 ? 101.766 85.622  92.626  1.00 98.26 ? 150 PHE A CD2 1 
ATOM   892  C  CE1 . PHE A 1 162 ? 104.079 85.637  91.125  1.00 98.26 ? 150 PHE A CE1 1 
ATOM   893  C  CE2 . PHE A 1 162 ? 102.993 85.505  93.249  1.00 98.26 ? 150 PHE A CE2 1 
ATOM   894  C  CZ  . PHE A 1 162 ? 104.152 85.513  92.497  1.00 98.26 ? 150 PHE A CZ  1 
ATOM   895  N  N   . GLN A 1 163 ? 98.088  87.456  88.988  1.00 97.54 ? 151 GLN A N   1 
ATOM   896  C  CA  . GLN A 1 163 ? 96.809  87.474  88.290  1.00 97.54 ? 151 GLN A CA  1 
ATOM   897  C  C   . GLN A 1 163 ? 96.947  88.150  86.933  1.00 97.54 ? 151 GLN A C   1 
ATOM   898  O  O   . GLN A 1 163 ? 96.143  87.916  86.042  1.00 97.54 ? 151 GLN A O   1 
ATOM   899  C  CB  . GLN A 1 163 ? 95.745  88.158  89.147  1.00 97.54 ? 151 GLN A CB  1 
ATOM   900  C  CG  . GLN A 1 163 ? 95.388  87.413  90.425  1.00 97.54 ? 151 GLN A CG  1 
ATOM   901  C  CD  . GLN A 1 163 ? 94.840  86.017  90.188  1.00 97.54 ? 151 GLN A CD  1 
ATOM   902  O  OE1 . GLN A 1 163 ? 94.063  85.801  89.260  1.00 97.54 ? 151 GLN A OE1 1 
ATOM   903  N  NE2 . GLN A 1 163 ? 95.237  85.065  91.025  1.00 97.54 ? 151 GLN A NE2 1 
ATOM   904  N  N   . SER A 1 164 ? 97.976  88.971  86.757  1.00 97.64 ? 152 SER A N   1 
ATOM   905  C  CA  . SER A 1 164 ? 98.170  89.673  85.490  1.00 97.64 ? 152 SER A CA  1 
ATOM   906  C  C   . SER A 1 164 ? 98.580  88.722  84.384  1.00 97.64 ? 152 SER A C   1 
ATOM   907  O  O   . SER A 1 164 ? 98.393  89.021  83.209  1.00 97.64 ? 152 SER A O   1 
ATOM   908  C  CB  . SER A 1 164 ? 99.227  90.762  85.626  1.00 97.64 ? 152 SER A CB  1 
ATOM   909  O  OG  . SER A 1 164 ? 98.861  91.711  86.607  1.00 97.64 ? 152 SER A OG  1 
ATOM   910  N  N   . PHE A 1 165 ? 99.140  87.577  84.752  1.00 96.62 ? 153 PHE A N   1 
ATOM   911  C  CA  . PHE A 1 165 ? 99.615  86.633  83.749  1.00 96.62 ? 153 PHE A CA  1 
ATOM   912  C  C   . PHE A 1 165 ? 98.509  85.726  83.243  1.00 96.62 ? 153 PHE A C   1 
ATOM   913  O  O   . PHE A 1 165 ? 98.506  84.538  83.556  1.00 96.62 ? 153 PHE A O   1 
ATOM   914  C  CB  . PHE A 1 165 ? 100.720 85.743  84.322  1.00 96.62 ? 153 PHE A CB  1 
ATOM   915  C  CG  . PHE A 1 165 ? 101.899 86.491  84.866  1.00 96.62 ? 153 PHE A CG  1 
ATOM   916  C  CD1 . PHE A 1 165 ? 102.567 87.421  84.094  1.00 96.62 ? 153 PHE A CD1 1 
ATOM   917  C  CD2 . PHE A 1 165 ? 102.365 86.227  86.142  1.00 96.62 ? 153 PHE A CD2 1 
ATOM   918  C  CE1 . PHE A 1 165 ? 103.662 88.097  84.595  1.00 96.62 ? 153 PHE A CE1 1 
ATOM   919  C  CE2 . PHE A 1 165 ? 103.459 86.899  86.649  1.00 96.62 ? 153 PHE A CE2 1 
ATOM   920  C  CZ  . PHE A 1 165 ? 104.109 87.836  85.874  1.00 96.62 ? 153 PHE A CZ  1 
ATOM   921  N  N   . GLN A 1 166 ? 97.581  86.258  82.456  1.00 94.49 ? 154 GLN A N   1 
ATOM   922  C  CA  . GLN A 1 166 ? 96.539  85.421  81.862  1.00 94.49 ? 154 GLN A CA  1 
ATOM   923  C  C   . GLN A 1 166 ? 95.977  86.058  80.601  1.00 94.49 ? 154 GLN A C   1 
ATOM   924  O  O   . GLN A 1 166 ? 96.204  87.242  80.354  1.00 94.49 ? 154 GLN A O   1 
ATOM   925  C  CB  . GLN A 1 166 ? 95.434  85.075  82.863  1.00 94.49 ? 154 GLN A CB  1 
ATOM   926  C  CG  . GLN A 1 166 ? 94.788  86.254  83.557  1.00 94.49 ? 154 GLN A CG  1 
ATOM   927  C  CD  . GLN A 1 166 ? 93.899  85.815  84.703  1.00 94.49 ? 154 GLN A CD  1 
ATOM   928  O  OE1 . GLN A 1 166 ? 92.673  85.891  84.620  1.00 94.49 ? 154 GLN A OE1 1 
ATOM   929  N  NE2 . GLN A 1 166 ? 94.515  85.338  85.778  1.00 94.49 ? 154 GLN A NE2 1 
ATOM   930  N  N   . LYS A 1 167 ? 95.250  85.286  79.800  1.00 91.81 ? 155 LYS A N   1 
ATOM   931  C  CA  . LYS A 1 167 ? 94.764  85.807  78.522  1.00 91.81 ? 155 LYS A CA  1 
ATOM   932  C  C   . LYS A 1 167 ? 93.795  86.964  78.681  1.00 91.81 ? 155 LYS A C   1 
ATOM   933  O  O   . LYS A 1 167 ? 93.878  87.947  77.948  1.00 91.81 ? 155 LYS A O   1 
ATOM   934  C  CB  . LYS A 1 167 ? 94.099  84.688  77.722  1.00 91.81 ? 155 LYS A CB  1 
ATOM   935  C  CG  . LYS A 1 167 ? 94.967  83.451  77.561  1.00 91.81 ? 155 LYS A CG  1 
ATOM   936  C  CD  . LYS A 1 167 ? 96.256  83.772  76.823  1.00 91.81 ? 155 LYS A CD  1 
ATOM   937  C  CE  . LYS A 1 167 ? 97.226  82.603  76.882  1.00 91.81 ? 155 LYS A CE  1 
ATOM   938  N  NZ  . LYS A 1 167 ? 97.585  82.264  78.287  1.00 91.81 ? 155 LYS A NZ  1 
ATOM   939  N  N   . GLU A 1 168 ? 92.880  86.861  79.634  1.00 93.25 ? 156 GLU A N   1 
ATOM   940  C  CA  . GLU A 1 168 ? 91.959  87.956  79.890  1.00 93.25 ? 156 GLU A CA  1 
ATOM   941  C  C   . GLU A 1 168 ? 92.243  88.472  81.281  1.00 93.25 ? 156 GLU A C   1 
ATOM   942  O  O   . GLU A 1 168 ? 92.214  87.708  82.239  1.00 93.25 ? 156 GLU A O   1 
ATOM   943  C  CB  . GLU A 1 168 ? 90.516  87.462  79.803  1.00 93.25 ? 156 GLU A CB  1 
ATOM   944  C  CG  . GLU A 1 168 ? 89.473  88.455  80.289  1.00 93.25 ? 156 GLU A CG  1 
ATOM   945  C  CD  . GLU A 1 168 ? 88.091  87.840  80.382  1.00 93.25 ? 156 GLU A CD  1 
ATOM   946  O  OE1 . GLU A 1 168 ? 87.849  86.817  79.710  1.00 93.25 ? 156 GLU A OE1 1 
ATOM   947  O  OE2 . GLU A 1 168 ? 87.246  88.379  81.126  1.00 93.25 ? 156 GLU A OE2 1 
ATOM   948  N  N   . LEU A 1 169 ? 92.550  89.759  81.400  1.00 95.75 ? 157 LEU A N   1 
ATOM   949  C  CA  . LEU A 1 169 ? 92.811  90.345  82.706  1.00 95.75 ? 157 LEU A CA  1 
ATOM   950  C  C   . LEU A 1 169 ? 91.617  90.080  83.599  1.00 95.75 ? 157 LEU A C   1 
ATOM   951  O  O   . LEU A 1 169 ? 90.475  90.244  83.179  1.00 95.75 ? 157 LEU A O   1 
ATOM   952  C  CB  . LEU A 1 169 ? 93.102  91.841  82.590  1.00 95.75 ? 157 LEU A CB  1 
ATOM   953  C  CG  . LEU A 1 169 ? 94.416  92.195  81.895  1.00 95.75 ? 157 LEU A CG  1 
ATOM   954  C  CD1 . LEU A 1 169 ? 94.568  93.701  81.755  1.00 95.75 ? 157 LEU A CD1 1 
ATOM   955  C  CD2 . LEU A 1 169 ? 95.596  91.599  82.646  1.00 95.75 ? 157 LEU A CD2 1 
ATOM   956  N  N   . PRO A 1 170 ? 91.870  89.668  84.841  1.00 95.83 ? 158 PRO A N   1 
ATOM   957  C  CA  . PRO A 1 170 ? 90.766  89.308  85.738  1.00 95.83 ? 158 PRO A CA  1 
ATOM   958  C  C   . PRO A 1 170 ? 89.830  90.468  86.051  1.00 95.83 ? 158 PRO A C   1 
ATOM   959  O  O   . PRO A 1 170 ? 88.619  90.267  86.114  1.00 95.83 ? 158 PRO A O   1 
ATOM   960  C  CB  . PRO A 1 170 ? 91.481  88.861  87.011  1.00 95.83 ? 158 PRO A CB  1 
ATOM   961  C  CG  . PRO A 1 170 ? 92.914  88.697  86.657  1.00 95.83 ? 158 PRO A CG  1 
ATOM   962  C  CD  . PRO A 1 170 ? 93.180  89.598  85.502  1.00 95.83 ? 158 PRO A CD  1 
ATOM   963  N  N   . TRP A 1 171 ? 90.375  91.662  86.246  1.00 95.20 ? 159 TRP A N   1 
ATOM   964  C  CA  . TRP A 1 171 ? 89.565  92.831  86.576  1.00 95.20 ? 159 TRP A CA  1 
ATOM   965  C  C   . TRP A 1 171 ? 88.720  93.344  85.422  1.00 95.20 ? 159 TRP A C   1 
ATOM   966  O  O   . TRP A 1 171 ? 87.855  94.180  85.621  1.00 95.20 ? 159 TRP A O   1 
ATOM   967  C  CB  . TRP A 1 171 ? 90.434  93.954  87.146  1.00 95.20 ? 159 TRP A CB  1 
ATOM   968  C  CG  . TRP A 1 171 ? 91.689  94.235  86.394  1.00 95.20 ? 159 TRP A CG  1 
ATOM   969  C  CD1 . TRP A 1 171 ? 91.844  95.099  85.353  1.00 95.20 ? 159 TRP A CD1 1 
ATOM   970  C  CD2 . TRP A 1 171 ? 92.981  93.672  86.645  1.00 95.20 ? 159 TRP A CD2 1 
ATOM   971  N  NE1 . TRP A 1 171 ? 93.150  95.100  84.930  1.00 95.20 ? 159 TRP A NE1 1 
ATOM   972  C  CE2 . TRP A 1 171 ? 93.868  94.230  85.708  1.00 95.20 ? 159 TRP A CE2 1 
ATOM   973  C  CE3 . TRP A 1 171 ? 93.470  92.742  87.565  1.00 95.20 ? 159 TRP A CE3 1 
ATOM   974  C  CZ2 . TRP A 1 171 ? 95.217  93.892  85.666  1.00 95.20 ? 159 TRP A CZ2 1 
ATOM   975  C  CZ3 . TRP A 1 171 ? 94.808  92.406  87.520  1.00 95.20 ? 159 TRP A CZ3 1 
ATOM   976  C  CH2 . TRP A 1 171 ? 95.666  92.980  86.579  1.00 95.20 ? 159 TRP A CH2 1 
ATOM   977  N  N   . ALA A 1 172 ? 89.002  92.894  84.210  1.00 93.12 ? 160 ALA A N   1 
ATOM   978  C  CA  . ALA A 1 172 ? 88.277  93.372  83.034  1.00 93.12 ? 160 ALA A CA  1 
ATOM   979  C  C   . ALA A 1 172 ? 86.776  93.081  82.941  1.00 93.12 ? 160 ALA A C   1 
ATOM   980  O  O   . ALA A 1 172 ? 86.028  93.939  82.483  1.00 93.12 ? 160 ALA A O   1 
ATOM   981  C  CB  . ALA A 1 172 ? 88.976  92.894  81.769  1.00 93.12 ? 160 ALA A CB  1 
ATOM   982  N  N   . HIS A 1 173 ? 86.318  91.897  83.344  1.00 92.31 ? 161 HIS A N   1 
ATOM   983  C  CA  . HIS A 1 173 ? 84.898  91.539  83.144  1.00 92.31 ? 161 HIS A CA  1 
ATOM   984  C  C   . HIS A 1 173 ? 84.136  90.893  84.301  1.00 92.31 ? 161 HIS A C   1 
ATOM   985  O  O   . HIS A 1 173 ? 84.738  90.441  85.270  1.00 92.31 ? 161 HIS A O   1 
ATOM   986  C  CB  . HIS A 1 173 ? 84.741  90.664  81.897  1.00 92.31 ? 161 HIS A CB  1 
ATOM   987  C  CG  . HIS A 1 173 ? 85.119  91.354  80.624  1.00 92.31 ? 161 HIS A CG  1 
ATOM   988  N  ND1 . HIS A 1 173 ? 84.330  92.322  80.041  1.00 92.31 ? 161 HIS A ND1 1 
ATOM   989  C  CD2 . HIS A 1 173 ? 86.204  91.221  79.824  1.00 92.31 ? 161 HIS A CD2 1 
ATOM   990  C  CE1 . HIS A 1 173 ? 84.912  92.755  78.936  1.00 92.31 ? 161 HIS A CE1 1 
ATOM   991  N  NE2 . HIS A 1 173 ? 86.050  92.103  78.782  1.00 92.31 ? 161 HIS A NE2 1 
ATOM   992  N  N   . CYS A 1 174 ? 82.807  90.882  84.225  1.00 91.54 ? 162 CYS A N   1 
ATOM   993  C  CA  . CYS A 1 174 ? 81.999  90.350  85.331  1.00 91.54 ? 162 CYS A CA  1 
ATOM   994  C  C   . CYS A 1 174 ? 81.656  88.882  85.170  1.00 91.54 ? 162 CYS A C   1 
ATOM   995  O  O   . CYS A 1 174 ? 80.884  88.331  85.953  1.00 91.54 ? 162 CYS A O   1 
ATOM   996  C  CB  . CYS A 1 174 ? 80.736  91.180  85.512  1.00 91.54 ? 162 CYS A CB  1 
ATOM   997  S  SG  . CYS A 1 174 ? 81.092  92.910  85.872  1.00 91.54 ? 162 CYS A SG  1 
ATOM   998  N  N   . ASN A 1 175 ? 82.228  88.241  84.163  1.00 90.87 ? 163 ASN A N   1 
ATOM   999  C  CA  . ASN A 1 175 ? 82.008  86.815  83.946  1.00 90.87 ? 163 ASN A CA  1 
ATOM   1000 C  C   . ASN A 1 175 ? 82.584  85.988  85.081  1.00 90.87 ? 163 ASN A C   1 
ATOM   1001 O  O   . ASN A 1 175 ? 82.091  84.898  85.364  1.00 90.87 ? 163 ASN A O   1 
ATOM   1002 C  CB  . ASN A 1 175 ? 82.632  86.387  82.620  1.00 90.87 ? 163 ASN A CB  1 
ATOM   1003 C  CG  . ASN A 1 175 ? 82.166  87.240  81.455  1.00 90.87 ? 163 ASN A CG  1 
ATOM   1004 O  OD1 . ASN A 1 175 ? 81.149  87.929  81.540  1.00 90.87 ? 163 ASN A OD1 1 
ATOM   1005 N  ND2 . ASN A 1 175 ? 82.909  87.194  80.356  1.00 90.87 ? 163 ASN A ND2 1 
ATOM   1006 N  N   . HIS A 1 176 ? 83.622  86.494  85.738  1.00 94.79 ? 164 HIS A N   1 
ATOM   1007 C  CA  . HIS A 1 176 ? 84.306  85.726  86.779  1.00 94.79 ? 164 HIS A CA  1 
ATOM   1008 C  C   . HIS A 1 176 ? 83.453  85.358  87.983  1.00 94.79 ? 164 HIS A C   1 
ATOM   1009 O  O   . HIS A 1 176 ? 82.519  86.076  88.332  1.00 94.79 ? 164 HIS A O   1 
ATOM   1010 C  CB  . HIS A 1 176 ? 85.559  86.472  87.228  1.00 94.79 ? 164 HIS A CB  1 
ATOM   1011 C  CG  . HIS A 1 176 ? 86.476  86.841  86.103  1.00 94.79 ? 164 HIS A CG  1 
ATOM   1012 N  ND1 . HIS A 1 176 ? 87.519  86.037  85.700  1.00 94.79 ? 164 HIS A ND1 1 
ATOM   1013 C  CD2 . HIS A 1 176 ? 86.504  87.926  85.294  1.00 94.79 ? 164 HIS A CD2 1 
ATOM   1014 C  CE1 . HIS A 1 176 ? 88.152  86.611  84.692  1.00 94.79 ? 164 HIS A CE1 1 
ATOM   1015 N  NE2 . HIS A 1 176 ? 87.555  87.759  84.426  1.00 94.79 ? 164 HIS A NE2 1 
ATOM   1016 N  N   . SER A 1 177 ? 83.770  84.233  88.618  1.00 95.56 ? 165 SER A N   1 
ATOM   1017 C  CA  . SER A 1 177 ? 82.962  83.737  89.736  1.00 95.56 ? 165 SER A CA  1 
ATOM   1018 C  C   . SER A 1 177 ? 82.869  84.653  90.948  1.00 95.56 ? 165 SER A C   1 
ATOM   1019 O  O   . SER A 1 177 ? 81.807  84.768  91.558  1.00 95.56 ? 165 SER A O   1 
ATOM   1020 C  CB  . SER A 1 177 ? 83.492  82.377  90.186  1.00 95.56 ? 165 SER A CB  1 
ATOM   1021 O  OG  . SER A 1 177 ? 84.845  82.474  90.596  1.00 95.56 ? 165 SER A OG  1 
ATOM   1022 N  N   . TRP A 1 178 ? 83.971  85.300  91.306  1.00 95.13 ? 166 TRP A N   1 
ATOM   1023 C  CA  . TRP A 1 178 ? 83.960  86.184  92.463  1.00 95.13 ? 166 TRP A CA  1 
ATOM   1024 C  C   . TRP A 1 178 ? 82.972  87.320  92.237  1.00 95.13 ? 166 TRP A C   1 
ATOM   1025 O  O   . TRP A 1 178 ? 82.272  87.730  93.150  1.00 95.13 ? 166 TRP A O   1 
ATOM   1026 C  CB  . TRP A 1 178 ? 85.358  86.705  92.817  1.00 95.13 ? 166 TRP A CB  1 
ATOM   1027 C  CG  . TRP A 1 178 ? 86.149  87.261  91.683  1.00 95.13 ? 166 TRP A CG  1 
ATOM   1028 C  CD1 . TRP A 1 178 ? 86.126  88.540  91.218  1.00 95.13 ? 166 TRP A CD1 1 
ATOM   1029 C  CD2 . TRP A 1 178 ? 87.112  86.562  90.888  1.00 95.13 ? 166 TRP A CD2 1 
ATOM   1030 N  NE1 . TRP A 1 178 ? 86.999  88.678  90.169  1.00 95.13 ? 166 TRP A NE1 1 
ATOM   1031 C  CE2 . TRP A 1 178 ? 87.621  87.477  89.950  1.00 95.13 ? 166 TRP A CE2 1 
ATOM   1032 C  CE3 . TRP A 1 178 ? 87.586  85.248  90.874  1.00 95.13 ? 166 TRP A CE3 1 
ATOM   1033 C  CZ2 . TRP A 1 178 ? 88.582  87.122  89.008  1.00 95.13 ? 166 TRP A CZ2 1 
ATOM   1034 C  CZ3 . TRP A 1 178 ? 88.540  84.898  89.939  1.00 95.13 ? 166 TRP A CZ3 1 
ATOM   1035 C  CH2 . TRP A 1 178 ? 89.027  85.831  89.018  1.00 95.13 ? 166 TRP A CH2 1 
ATOM   1036 N  N   . ASN A 1 179 ? 82.893  87.822  91.014  1.00 95.91 ? 167 ASN A N   1 
ATOM   1037 C  CA  . ASN A 1 179 ? 81.994  88.931  90.727  1.00 95.91 ? 167 ASN A CA  1 
ATOM   1038 C  C   . ASN A 1 179 ? 80.559  88.611  91.116  1.00 95.91 ? 167 ASN A C   1 
ATOM   1039 O  O   . ASN A 1 179 ? 80.013  87.589  90.705  1.00 95.91 ? 167 ASN A O   1 
ATOM   1040 C  CB  . ASN A 1 179 ? 82.100  89.343  89.263  1.00 95.91 ? 167 ASN A CB  1 
ATOM   1041 C  CG  . ASN A 1 179 ? 83.470  89.888  88.919  1.00 95.91 ? 167 ASN A CG  1 
ATOM   1042 O  OD1 . ASN A 1 179 ? 84.008  90.736  89.628  1.00 95.91 ? 167 ASN A OD1 1 
ATOM   1043 N  ND2 . ASN A 1 179 ? 84.044  89.401  87.831  1.00 95.91 ? 167 ASN A ND2 1 
ATOM   1044 N  N   . THR A 1 180 ? 79.945  89.483  91.907  1.00 93.30 ? 168 THR A N   1 
ATOM   1045 C  CA  . THR A 1 180 ? 78.573  89.267  92.371  1.00 93.30 ? 168 THR A CA  1 
ATOM   1046 C  C   . THR A 1 180 ? 77.531  89.573  91.309  1.00 93.30 ? 168 THR A C   1 
ATOM   1047 O  O   . THR A 1 180 ? 77.862  90.095  90.245  1.00 93.30 ? 168 THR A O   1 
ATOM   1048 C  CB  . THR A 1 180 ? 78.255  90.114  93.623  1.00 93.30 ? 168 THR A CB  1 
ATOM   1049 O  OG1 . THR A 1 180 ? 78.546  91.492  93.369  1.00 93.30 ? 168 THR A OG1 1 
ATOM   1050 C  CG2 . THR A 1 180 ? 79.049  89.629  94.809  1.00 93.30 ? 168 THR A CG2 1 
ATOM   1051 N  N   . PRO A 1 181 ? 76.257  89.250  91.592  1.00 89.35 ? 169 PRO A N   1 
ATOM   1052 C  CA  . PRO A 1 181 ? 75.209  89.613  90.639  1.00 89.35 ? 169 PRO A CA  1 
ATOM   1053 C  C   . PRO A 1 181 ? 75.203  91.113  90.393  1.00 89.35 ? 169 PRO A C   1 
ATOM   1054 O  O   . PRO A 1 181 ? 74.861  91.536  89.291  1.00 89.35 ? 169 PRO A O   1 
ATOM   1055 C  CB  . PRO A 1 181 ? 73.916  89.204  91.360  1.00 89.35 ? 169 PRO A CB  1 
ATOM   1056 C  CG  . PRO A 1 181 ? 74.326  88.542  92.641  1.00 89.35 ? 169 PRO A CG  1 
ATOM   1057 C  CD  . PRO A 1 181 ? 75.779  88.211  92.517  1.00 89.35 ? 169 PRO A CD  1 
ATOM   1058 N  N   . HIS A 1 182 ? 75.568  91.907  91.393  1.00 88.40 ? 170 HIS A N   1 
ATOM   1059 C  CA  . HIS A 1 182 ? 75.636  93.347  91.203  1.00 88.40 ? 170 HIS A CA  1 
ATOM   1060 C  C   . HIS A 1 182 ? 76.929  93.796  90.530  1.00 88.40 ? 170 HIS A C   1 
ATOM   1061 O  O   . HIS A 1 182 ? 77.661  94.611  91.085  1.00 88.40 ? 170 HIS A O   1 
ATOM   1062 C  CB  . HIS A 1 182 ? 75.501  94.051  92.555  1.00 88.40 ? 170 HIS A CB  1 
ATOM   1063 C  CG  . HIS A 1 182 ? 74.122  93.989  93.135  1.00 88.40 ? 170 HIS A CG  1 
ATOM   1064 N  ND1 . HIS A 1 182 ? 73.389  95.117  93.430  1.00 88.40 ? 170 HIS A ND1 1 
ATOM   1065 C  CD2 . HIS A 1 182 ? 73.339  92.935  93.464  1.00 88.40 ? 170 HIS A CD2 1 
ATOM   1066 C  CE1 . HIS A 1 182 ? 72.215  94.762  93.920  1.00 88.40 ? 170 HIS A CE1 1 
ATOM   1067 N  NE2 . HIS A 1 182 ? 72.159  93.443  93.950  1.00 88.40 ? 170 HIS A NE2 1 
ATOM   1068 N  N   . CYS A 1 183 ? 77.194  93.304  89.322  1.00 90.60 ? 171 CYS A N   1 
ATOM   1069 C  CA  . CYS A 1 183 ? 78.377  93.722  88.574  1.00 90.60 ? 171 CYS A CA  1 
ATOM   1070 C  C   . CYS A 1 183 ? 77.940  94.140  87.191  1.00 90.60 ? 171 CYS A C   1 
ATOM   1071 O  O   . CYS A 1 183 ? 77.162  93.435  86.551  1.00 90.60 ? 171 CYS A O   1 
ATOM   1072 C  CB  . CYS A 1 183 ? 79.390  92.583  88.452  1.00 90.60 ? 171 CYS A CB  1 
ATOM   1073 S  SG  . CYS A 1 183 ? 81.059  93.058  87.913  1.00 90.60 ? 171 CYS A SG  1 
ATOM   1074 N  N   . MET A 1 184 ? 78.433  95.280  86.724  1.00 87.51 ? 172 MET A N   1 
ATOM   1075 C  CA  . MET A 1 184 ? 78.127  95.726  85.373  1.00 87.51 ? 172 MET A CA  1 
ATOM   1076 C  C   . MET A 1 184 ? 79.369  96.387  84.816  1.00 87.51 ? 172 MET A C   1 
ATOM   1077 O  O   . MET A 1 184 ? 80.039  97.146  85.515  1.00 87.51 ? 172 MET A O   1 
ATOM   1078 C  CB  . MET A 1 184 ? 76.946  96.695  85.359  1.00 87.51 ? 172 MET A CB  1 
ATOM   1079 C  CG  . MET A 1 184 ? 76.445  97.031  83.964  1.00 87.51 ? 172 MET A CG  1 
ATOM   1080 S  SD  . MET A 1 184 ? 74.931  98.007  83.950  1.00 87.51 ? 172 MET A SD  1 
ATOM   1081 C  CE  . MET A 1 184 ? 73.741  96.797  84.519  1.00 87.51 ? 172 MET A CE  1 
ATOM   1082 N  N   . GLU A 1 185 ? 79.688  96.097  83.561  1.00 84.73 ? 173 GLU A N   1 
ATOM   1083 C  CA  . GLU A 1 185 ? 80.876  96.668  82.946  1.00 84.73 ? 173 GLU A CA  1 
ATOM   1084 C  C   . GLU A 1 185 ? 80.717  98.165  82.773  1.00 84.73 ? 173 GLU A C   1 
ATOM   1085 O  O   . GLU A 1 185 ? 79.613  98.650  82.551  1.00 84.73 ? 173 GLU A O   1 
ATOM   1086 C  CB  . GLU A 1 185 ? 81.165  95.996  81.604  1.00 84.73 ? 173 GLU A CB  1 
ATOM   1087 C  CG  . GLU A 1 185 ? 82.593  95.492  81.461  1.00 84.73 ? 173 GLU A CG  1 
ATOM   1088 C  CD  . GLU A 1 185 ? 83.600  96.616  81.312  1.00 84.73 ? 173 GLU A CD  1 
ATOM   1089 O  OE1 . GLU A 1 185 ? 83.328  97.563  80.545  1.00 84.73 ? 173 GLU A OE1 1 
ATOM   1090 O  OE2 . GLU A 1 185 ? 84.667  96.552  81.956  1.00 84.73 ? 173 GLU A OE2 1 
ATOM   1091 N  N   . ASP A 1 186 ? 81.818  98.899  82.857  1.00 72.72 ? 174 ASP A N   1 
ATOM   1092 C  CA  . ASP A 1 186 ? 81.759  100.352 82.759  1.00 72.72 ? 174 ASP A CA  1 
ATOM   1093 C  C   . ASP A 1 186 ? 81.209  100.806 81.421  1.00 72.72 ? 174 ASP A C   1 
ATOM   1094 O  O   . ASP A 1 186 ? 80.463  101.777 81.355  1.00 72.72 ? 174 ASP A O   1 
ATOM   1095 C  CB  . ASP A 1 186 ? 83.147  100.941 82.983  1.00 72.72 ? 174 ASP A CB  1 
ATOM   1096 C  CG  . ASP A 1 186 ? 83.675  100.650 84.365  1.00 72.72 ? 174 ASP A CG  1 
ATOM   1097 O  OD1 . ASP A 1 186 ? 82.875  100.205 85.211  1.00 72.72 ? 174 ASP A OD1 1 
ATOM   1098 O  OD2 . ASP A 1 186 ? 84.880  100.866 84.608  1.00 72.72 ? 174 ASP A OD2 1 
ATOM   1099 N  N   . THR A 1 187 ? 81.576  100.110 80.353  1.00 70.62 ? 175 THR A N   1 
ATOM   1100 C  CA  . THR A 1 187 ? 81.061  100.453 79.035  1.00 70.62 ? 175 THR A CA  1 
ATOM   1101 C  C   . THR A 1 187 ? 79.556  100.261 78.998  1.00 70.62 ? 175 THR A C   1 
ATOM   1102 O  O   . THR A 1 187 ? 78.841  101.061 78.401  1.00 70.62 ? 175 THR A O   1 
ATOM   1103 C  CB  . THR A 1 187 ? 81.719  99.606  77.936  1.00 70.62 ? 175 THR A CB  1 
ATOM   1104 O  OG1 . THR A 1 187 ? 81.535  98.216  78.229  1.00 70.62 ? 175 THR A OG1 1 
ATOM   1105 C  CG2 . THR A 1 187 ? 83.206  99.907  77.860  1.00 70.62 ? 175 THR A CG2 1 
ATOM   1106 N  N   . MET A 1 188 ? 79.067  99.194  79.618  1.00 69.54 ? 176 MET A N   1 
ATOM   1107 C  CA  . MET A 1 188 ? 77.625  98.971  79.690  1.00 69.54 ? 176 MET A CA  1 
ATOM   1108 C  C   . MET A 1 188 ? 76.960  100.072 80.494  1.00 69.54 ? 176 MET A C   1 
ATOM   1109 O  O   . MET A 1 188 ? 75.868  100.522 80.156  1.00 69.54 ? 176 MET A O   1 
ATOM   1110 C  CB  . MET A 1 188 ? 77.314  97.597  80.281  1.00 69.54 ? 176 MET A CB  1 
ATOM   1111 C  CG  . MET A 1 188 ? 76.743  96.614  79.275  1.00 69.54 ? 176 MET A CG  1 
ATOM   1112 S  SD  . MET A 1 188 ? 77.752  96.454  77.789  1.00 69.54 ? 176 MET A SD  1 
ATOM   1113 C  CE  . MET A 1 188 ? 79.157  95.543  78.422  1.00 69.54 ? 176 MET A CE  1 
ATOM   1114 N  N   . ARG A 1 189 ? 77.611  100.505 81.567  1.00 65.76 ? 177 ARG A N   1 
ATOM   1115 C  CA  . ARG A 1 189 ? 77.072  101.600 82.360  1.00 65.76 ? 177 ARG A CA  1 
ATOM   1116 C  C   . ARG A 1 189 ? 77.001  102.859 81.513  1.00 65.76 ? 177 ARG A C   1 
ATOM   1117 O  O   . ARG A 1 189 ? 76.043  103.623 81.606  1.00 65.76 ? 177 ARG A O   1 
ATOM   1118 C  CB  . ARG A 1 189 ? 77.894  101.819 83.630  1.00 65.76 ? 177 ARG A CB  1 
ATOM   1119 C  CG  . ARG A 1 189 ? 77.877  100.618 84.558  1.00 65.76 ? 177 ARG A CG  1 
ATOM   1120 C  CD  . ARG A 1 189 ? 78.723  100.828 85.800  1.00 65.76 ? 177 ARG A CD  1 
ATOM   1121 N  NE  . ARG A 1 189 ? 78.068  101.698 86.770  1.00 65.76 ? 177 ARG A NE  1 
ATOM   1122 C  CZ  . ARG A 1 189 ? 78.529  101.924 87.994  1.00 65.76 ? 177 ARG A CZ  1 
ATOM   1123 N  NH1 . ARG A 1 189 ? 79.646  101.338 88.402  1.00 65.76 ? 177 ARG A NH1 1 
ATOM   1124 N  NH2 . ARG A 1 189 ? 77.872  102.729 88.815  1.00 65.76 ? 177 ARG A NH2 1 
ATOM   1125 N  N   . LYS A 1 190 ? 78.004  103.069 80.669  1.00 64.03 ? 178 LYS A N   1 
ATOM   1126 C  CA  . LYS A 1 190 ? 78.005  104.238 79.797  1.00 64.03 ? 178 LYS A CA  1 
ATOM   1127 C  C   . LYS A 1 190 ? 76.787  104.226 78.888  1.00 64.03 ? 178 LYS A C   1 
ATOM   1128 O  O   . LYS A 1 190 ? 76.175  105.266 78.650  1.00 64.03 ? 178 LYS A O   1 
ATOM   1129 C  CB  . LYS A 1 190 ? 79.289  104.299 78.968  1.00 64.03 ? 178 LYS A CB  1 
ATOM   1130 N  N   . ASN A 1 191 ? 76.430  103.050 78.382  1.00 65.69 ? 179 ASN A N   1 
ATOM   1131 C  CA  . ASN A 1 191 ? 75.304  102.970 77.467  1.00 65.69 ? 179 ASN A CA  1 
ATOM   1132 C  C   . ASN A 1 191 ? 74.030  103.355 78.187  1.00 65.69 ? 179 ASN A C   1 
ATOM   1133 O  O   . ASN A 1 191 ? 73.753  102.866 79.284  1.00 65.69 ? 179 ASN A O   1 
ATOM   1134 C  CB  . ASN A 1 191 ? 75.176  101.563 76.880  1.00 65.69 ? 179 ASN A CB  1 
ATOM   1135 C  CG  . ASN A 1 191 ? 74.182  101.495 75.734  1.00 65.69 ? 179 ASN A CG  1 
ATOM   1136 O  OD1 . ASN A 1 191 ? 73.771  102.518 75.186  1.00 65.69 ? 179 ASN A OD1 1 
ATOM   1137 N  ND2 . ASN A 1 191 ? 73.799  100.282 75.357  1.00 65.69 ? 179 ASN A ND2 1 
ATOM   1138 N  N   . LYS A 1 192 ? 73.245  104.225 77.566  1.00 61.72 ? 180 LYS A N   1 
ATOM   1139 C  CA  . LYS A 1 192 ? 71.986  104.644 78.160  1.00 61.72 ? 180 LYS A CA  1 
ATOM   1140 C  C   . LYS A 1 192 ? 71.023  103.482 78.264  1.00 61.72 ? 180 LYS A C   1 
ATOM   1141 O  O   . LYS A 1 192 ? 70.336  103.328 79.268  1.00 61.72 ? 180 LYS A O   1 
ATOM   1142 C  CB  . LYS A 1 192 ? 71.346  105.765 77.333  1.00 61.72 ? 180 LYS A CB  1 
ATOM   1143 C  CG  . LYS A 1 192 ? 72.089  107.094 77.351  1.00 61.72 ? 180 LYS A CG  1 
ATOM   1144 C  CD  . LYS A 1 192 ? 73.184  107.164 76.296  1.00 61.72 ? 180 LYS A CD  1 
ATOM   1145 C  CE  . LYS A 1 192 ? 72.630  106.901 74.905  1.00 61.72 ? 180 LYS A CE  1 
ATOM   1146 N  NZ  . LYS A 1 192 ? 73.705  106.900 73.875  1.00 61.72 ? 180 LYS A NZ  1 
ATOM   1147 N  N   . SER A 1 193 ? 70.968  102.655 77.228  1.00 64.32 ? 181 SER A N   1 
ATOM   1148 C  CA  . SER A 1 193 ? 69.999  101.570 77.229  1.00 64.32 ? 181 SER A CA  1 
ATOM   1149 C  C   . SER A 1 193 ? 70.232  100.570 78.350  1.00 64.32 ? 181 SER A C   1 
ATOM   1150 O  O   . SER A 1 193 ? 69.294  100.159 79.028  1.00 64.32 ? 181 SER A O   1 
ATOM   1151 C  CB  . SER A 1 193 ? 70.027  100.846 75.883  1.00 64.32 ? 181 SER A CB  1 
ATOM   1152 O  OG  . SER A 1 193 ? 69.787  101.746 74.816  1.00 64.32 ? 181 SER A OG  1 
ATOM   1153 N  N   . VAL A 1 194 ? 71.482  100.169 78.545  1.00 59.06 ? 182 VAL A N   1 
ATOM   1154 C  CA  . VAL A 1 194 ? 71.787  99.229  79.613  1.00 59.06 ? 182 VAL A CA  1 
ATOM   1155 C  C   . VAL A 1 194 ? 71.599  99.781  81.025  1.00 59.06 ? 182 VAL A C   1 
ATOM   1156 O  O   . VAL A 1 194 ? 71.014  99.115  81.881  1.00 59.06 ? 182 VAL A O   1 
ATOM   1157 C  CB  . VAL A 1 194 ? 73.204  98.645  79.461  1.00 59.06 ? 182 VAL A CB  1 
ATOM   1158 C  CG1 . VAL A 1 194 ? 73.411  97.507  80.447  1.00 59.06 ? 182 VAL A CG1 1 
ATOM   1159 C  CG2 . VAL A 1 194 ? 73.409  98.143  78.042  1.00 59.06 ? 182 VAL A CG2 1 
ATOM   1160 N  N   . TRP A 1 195 ? 72.063  101.002 81.273  1.00 56.84 ? 183 TRP A N   1 
ATOM   1161 C  CA  . TRP A 1 195 ? 71.993  101.525 82.636  1.00 56.84 ? 183 TRP A CA  1 
ATOM   1162 C  C   . TRP A 1 195 ? 70.905  102.558 82.913  1.00 56.84 ? 183 TRP A C   1 
ATOM   1163 O  O   . TRP A 1 195 ? 70.159  102.427 83.877  1.00 56.84 ? 183 TRP A O   1 
ATOM   1164 C  CB  . TRP A 1 195 ? 73.352  102.094 83.049  1.00 56.84 ? 183 TRP A CB  1 
ATOM   1165 N  N   . ILE A 1 196 ? 70.827  103.604 82.100  1.00 60.37 ? 184 ILE A N   1 
ATOM   1166 C  CA  . ILE A 1 196 ? 69.846  104.646 82.373  1.00 60.37 ? 184 ILE A CA  1 
ATOM   1167 C  C   . ILE A 1 196 ? 68.428  104.108 82.231  1.00 60.37 ? 184 ILE A C   1 
ATOM   1168 O  O   . ILE A 1 196 ? 67.573  104.352 83.085  1.00 60.37 ? 184 ILE A O   1 
ATOM   1169 C  CB  . ILE A 1 196 ? 70.064  105.875 81.469  1.00 60.37 ? 184 ILE A CB  1 
ATOM   1170 C  CG1 . ILE A 1 196 ? 71.479  106.421 81.666  1.00 60.37 ? 184 ILE A CG1 1 
ATOM   1171 C  CG2 . ILE A 1 196 ? 69.037  106.959 81.760  1.00 60.37 ? 184 ILE A CG2 1 
ATOM   1172 C  CD1 . ILE A 1 196 ? 71.699  107.784 81.050  1.00 60.37 ? 184 ILE A CD1 1 
ATOM   1173 N  N   . THR A 1 197 ? 68.180  103.354 81.166  1.00 60.77 ? 185 THR A N   1 
ATOM   1174 C  CA  . THR A 1 197 ? 66.861  102.764 80.957  1.00 60.77 ? 185 THR A CA  1 
ATOM   1175 C  C   . THR A 1 197 ? 66.503  101.711 82.000  1.00 60.77 ? 185 THR A C   1 
ATOM   1176 O  O   . THR A 1 197 ? 65.375  101.679 82.493  1.00 60.77 ? 185 THR A O   1 
ATOM   1177 C  CB  . THR A 1 197 ? 66.743  102.162 79.543  1.00 60.77 ? 185 THR A CB  1 
ATOM   1178 O  OG1 . THR A 1 197 ? 67.189  103.121 78.577  1.00 60.77 ? 185 THR A OG1 1 
ATOM   1179 C  CG2 . THR A 1 197 ? 65.306  101.766 79.233  1.00 60.77 ? 185 THR A CG2 1 
ATOM   1180 N  N   . ILE A 1 198 ? 67.461  100.864 82.363  1.00 56.46 ? 186 ILE A N   1 
ATOM   1181 C  CA  . ILE A 1 198 ? 67.158  99.774  83.289  1.00 56.46 ? 186 ILE A CA  1 
ATOM   1182 C  C   . ILE A 1 198 ? 67.768  99.989  84.664  1.00 56.46 ? 186 ILE A C   1 
ATOM   1183 O  O   . ILE A 1 198 ? 68.983  100.099 84.798  1.00 56.46 ? 186 ILE A O   1 
ATOM   1184 C  CB  . ILE A 1 198 ? 67.671  98.430  82.736  1.00 56.46 ? 186 ILE A CB  1 
ATOM   1185 C  CG1 . ILE A 1 198 ? 67.288  98.273  81.263  1.00 56.46 ? 186 ILE A CG1 1 
ATOM   1186 C  CG2 . ILE A 1 198 ? 67.137  97.267  83.560  1.00 56.46 ? 186 ILE A CG2 1 
ATOM   1187 C  CD1 . ILE A 1 198 ? 67.869  97.039  80.611  1.00 56.46 ? 186 ILE A CD1 1 
ATOM   1188 N  N   . SER A 1 199 ? 66.930  100.000 85.694  1.00 58.81 ? 187 SER A N   1 
ATOM   1189 C  CA  . SER A 1 199 ? 67.420  100.231 87.048  1.00 58.81 ? 187 SER A CA  1 
ATOM   1190 C  C   . SER A 1 199 ? 68.353  99.124  87.508  1.00 58.81 ? 187 SER A C   1 
ATOM   1191 O  O   . SER A 1 199 ? 68.106  97.947  87.244  1.00 58.81 ? 187 SER A O   1 
ATOM   1192 C  CB  . SER A 1 199 ? 66.249  100.363 88.023  1.00 58.81 ? 187 SER A CB  1 
ATOM   1193 O  OG  . SER A 1 199 ? 65.457  99.189  88.029  1.00 58.81 ? 187 SER A OG  1 
ATOM   1194 N  N   . SER A 1 200 ? 69.420  99.498  88.206  1.00 55.61 ? 188 SER A N   1 
ATOM   1195 C  CA  . SER A 1 200 ? 70.373  98.512  88.707  1.00 55.61 ? 188 SER A CA  1 
ATOM   1196 C  C   . SER A 1 200 ? 70.989  98.999  90.012  1.00 55.61 ? 188 SER A C   1 
ATOM   1197 O  O   . SER A 1 200 ? 72.151  99.406  90.037  1.00 55.61 ? 188 SER A O   1 
ATOM   1198 C  CB  . SER A 1 200 ? 71.466  98.244  87.667  1.00 55.61 ? 188 SER A CB  1 
ATOM   1199 O  OG  . SER A 1 200 ? 72.060  99.450  87.220  1.00 55.61 ? 188 SER A OG  1 
ATOM   1200 N  N   . THR A 1 201 ? 70.215  98.963  91.095  1.00 57.44 ? 189 THR A N   1 
ATOM   1201 C  CA  . THR A 1 201 ? 70.713  99.458  92.376  1.00 57.44 ? 189 THR A CA  1 
ATOM   1202 C  C   . THR A 1 201 ? 72.053  98.907  92.818  1.00 57.44 ? 189 THR A C   1 
ATOM   1203 O  O   . THR A 1 201 ? 72.284  97.706  92.721  1.00 57.44 ? 189 THR A O   1 
ATOM   1204 C  CB  . THR A 1 201 ? 69.696  99.188  93.500  1.00 57.44 ? 189 THR A CB  1 
ATOM   1205 O  OG1 . THR A 1 201 ? 69.487  97.776  93.628  1.00 57.44 ? 189 THR A OG1 1 
ATOM   1206 C  CG2 . THR A 1 201 ? 68.373  99.866  93.190  1.00 57.44 ? 189 THR A CG2 1 
ATOM   1207 N  N   . ASN A 1 202 ? 72.942  99.780  93.284  1.00 71.16 ? 190 ASN A N   1 
ATOM   1208 C  CA  . ASN A 1 202 ? 74.231  99.339  93.835  1.00 71.16 ? 190 ASN A CA  1 
ATOM   1209 C  C   . ASN A 1 202 ? 75.102  98.446  92.954  1.00 71.16 ? 190 ASN A C   1 
ATOM   1210 O  O   . ASN A 1 202 ? 75.726  97.515  93.457  1.00 71.16 ? 190 ASN A O   1 
ATOM   1211 C  CB  . ASN A 1 202 ? 74.030  98.678  95.205  1.00 71.16 ? 190 ASN A CB  1 
ATOM   1212 C  CG  . ASN A 1 202 ? 73.452  99.631  96.232  1.00 71.16 ? 190 ASN A CG  1 
ATOM   1213 O  OD1 . ASN A 1 202 ? 73.337  100.832 95.987  1.00 71.16 ? 190 ASN A OD1 1 
ATOM   1214 N  ND2 . ASN A 1 202 ? 73.090  99.100  97.392  1.00 71.16 ? 190 ASN A ND2 1 
ATOM   1215 N  N   . PHE A 1 203 ? 75.161  98.717  91.656  1.00 80.01 ? 191 PHE A N   1 
ATOM   1216 C  CA  . PHE A 1 203 ? 76.039  97.930  90.793  1.00 80.01 ? 191 PHE A CA  1 
ATOM   1217 C  C   . PHE A 1 203 ? 77.466  98.439  90.868  1.00 80.01 ? 191 PHE A C   1 
ATOM   1218 O  O   . PHE A 1 203 ? 77.693  99.647  90.872  1.00 80.01 ? 191 PHE A O   1 
ATOM   1219 C  CB  . PHE A 1 203 ? 75.508  97.862  89.364  1.00 80.01 ? 191 PHE A CB  1 
ATOM   1220 C  CG  . PHE A 1 203 ? 74.621  96.674  89.117  1.00 80.01 ? 191 PHE A CG  1 
ATOM   1221 C  CD1 . PHE A 1 203 ? 73.566  96.392  89.967  1.00 80.01 ? 191 PHE A CD1 1 
ATOM   1222 C  CD2 . PHE A 1 203 ? 74.849  95.831  88.048  1.00 80.01 ? 191 PHE A CD2 1 
ATOM   1223 C  CE1 . PHE A 1 203 ? 72.749  95.301  89.749  1.00 80.01 ? 191 PHE A CE1 1 
ATOM   1224 C  CE2 . PHE A 1 203 ? 74.038  94.736  87.821  1.00 80.01 ? 191 PHE A CE2 1 
ATOM   1225 C  CZ  . PHE A 1 203 ? 72.985  94.470  88.673  1.00 80.01 ? 191 PHE A CZ  1 
ATOM   1226 N  N   . THR A 1 204 ? 78.432  97.531  90.928  1.00 86.05 ? 192 THR A N   1 
ATOM   1227 C  CA  . THR A 1 204 ? 79.821  97.947  91.112  1.00 86.05 ? 192 THR A CA  1 
ATOM   1228 C  C   . THR A 1 204 ? 80.762  97.561  89.991  1.00 86.05 ? 192 THR A C   1 
ATOM   1229 O  O   . THR A 1 204 ? 80.621  96.497  89.393  1.00 86.05 ? 192 THR A O   1 
ATOM   1230 C  CB  . THR A 1 204 ? 80.392  97.402  92.431  1.00 86.05 ? 192 THR A CB  1 
ATOM   1231 O  OG1 . THR A 1 204 ? 79.628  97.918  93.527  1.00 86.05 ? 192 THR A OG1 1 
ATOM   1232 C  CG2 . THR A 1 204 ? 81.841  97.825  92.599  1.00 86.05 ? 192 THR A CG2 1 
ATOM   1233 N  N   . SER A 1 205 ? 81.724  98.431  89.705  1.00 88.52 ? 193 SER A N   1 
ATOM   1234 C  CA  . SER A 1 205 ? 82.691  98.165  88.647  1.00 88.52 ? 193 SER A CA  1 
ATOM   1235 C  C   . SER A 1 205 ? 83.440  96.831  88.845  1.00 88.52 ? 193 SER A C   1 
ATOM   1236 O  O   . SER A 1 205 ? 83.744  96.477  89.981  1.00 88.52 ? 193 SER A O   1 
ATOM   1237 C  CB  . SER A 1 205 ? 83.687  99.321  88.547  1.00 88.52 ? 193 SER A CB  1 
ATOM   1238 O  OG  . SER A 1 205 ? 84.674  99.081  87.560  1.00 88.52 ? 193 SER A OG  1 
ATOM   1239 N  N   . PRO A 1 206 ? 83.743  96.082  87.750  1.00 92.91 ? 194 PRO A N   1 
ATOM   1240 C  CA  . PRO A 1 206 ? 84.438  94.827  88.028  1.00 92.91 ? 194 PRO A CA  1 
ATOM   1241 C  C   . PRO A 1 206 ? 85.757  95.048  88.757  1.00 92.91 ? 194 PRO A C   1 
ATOM   1242 O  O   . PRO A 1 206 ? 86.086  94.252  89.623  1.00 92.91 ? 194 PRO A O   1 
ATOM   1243 C  CB  . PRO A 1 206 ? 84.681  94.239  86.635  1.00 92.91 ? 194 PRO A CB  1 
ATOM   1244 C  CG  . PRO A 1 206 ? 84.408  95.341  85.663  1.00 92.91 ? 194 PRO A CG  1 
ATOM   1245 C  CD  . PRO A 1 206 ? 83.405  96.229  86.326  1.00 92.91 ? 194 PRO A CD  1 
ATOM   1246 N  N   . VAL A 1 207 ? 86.503  96.090  88.410  1.00 92.58 ? 195 VAL A N   1 
ATOM   1247 C  CA  . VAL A 1 207 ? 87.751  96.379  89.099  1.00 92.58 ? 195 VAL A CA  1 
ATOM   1248 C  C   . VAL A 1 207 ? 87.538  96.508  90.600  1.00 92.58 ? 195 VAL A C   1 
ATOM   1249 O  O   . VAL A 1 207 ? 88.344  96.012  91.384  1.00 92.58 ? 195 VAL A O   1 
ATOM   1250 C  CB  . VAL A 1 207 ? 88.409  97.659  88.569  1.00 92.58 ? 195 VAL A CB  1 
ATOM   1251 C  CG1 . VAL A 1 207 ? 89.890  97.660  88.910  1.00 92.58 ? 195 VAL A CG1 1 
ATOM   1252 C  CG2 . VAL A 1 207 ? 88.224  97.758  87.064  1.00 92.58 ? 195 VAL A CG2 1 
ATOM   1253 N  N   . ILE A 1 208 ? 86.460  97.171  91.009  1.00 90.72 ? 196 ILE A N   1 
ATOM   1254 C  CA  . ILE A 1 208 ? 86.157  97.317  92.431  1.00 90.72 ? 196 ILE A CA  1 
ATOM   1255 C  C   . ILE A 1 208 ? 85.816  95.972  93.051  1.00 90.72 ? 196 ILE A C   1 
ATOM   1256 O  O   . ILE A 1 208 ? 86.289  95.650  94.135  1.00 90.72 ? 196 ILE A O   1 
ATOM   1257 C  CB  . ILE A 1 208 ? 84.987  98.287  92.665  1.00 90.72 ? 196 ILE A CB  1 
ATOM   1258 C  CG1 . ILE A 1 208 ? 85.240  99.611  91.948  1.00 90.72 ? 196 ILE A CG1 1 
ATOM   1259 C  CG2 . ILE A 1 208 ? 84.772  98.532  94.149  1.00 90.72 ? 196 ILE A CG2 1 
ATOM   1260 C  CD1 . ILE A 1 208 ? 84.074  100.571 92.020  1.00 90.72 ? 196 ILE A CD1 1 
ATOM   1261 N  N   . GLU A 1 209 ? 85.022  95.168  92.353  1.00 94.13 ? 197 GLU A N   1 
ATOM   1262 C  CA  . GLU A 1 209 ? 84.672  93.848  92.858  1.00 94.13 ? 197 GLU A CA  1 
ATOM   1263 C  C   . GLU A 1 209 ? 85.892  92.961  92.979  1.00 94.13 ? 197 GLU A C   1 
ATOM   1264 O  O   . GLU A 1 209 ? 86.031  92.225  93.939  1.00 94.13 ? 197 GLU A O   1 
ATOM   1265 C  CB  . GLU A 1 209 ? 83.654  93.171  91.951  1.00 94.13 ? 197 GLU A CB  1 
ATOM   1266 C  CG  . GLU A 1 209 ? 82.297  93.840  91.921  1.00 94.13 ? 197 GLU A CG  1 
ATOM   1267 C  CD  . GLU A 1 209 ? 81.175  92.860  92.176  1.00 94.13 ? 197 GLU A CD  1 
ATOM   1268 O  OE1 . GLU A 1 209 ? 81.468  91.721  92.594  1.00 94.13 ? 197 GLU A OE1 1 
ATOM   1269 O  OE2 . GLU A 1 209 ? 80.004  93.229  91.967  1.00 94.13 ? 197 GLU A OE2 1 
ATOM   1270 N  N   . PHE A 1 210 ? 86.776  93.019  91.994  1.00 95.91 ? 198 PHE A N   1 
ATOM   1271 C  CA  . PHE A 1 210 ? 87.960  92.185  92.024  1.00 95.91 ? 198 PHE A CA  1 
ATOM   1272 C  C   . PHE A 1 210 ? 88.827  92.555  93.213  1.00 95.91 ? 198 PHE A C   1 
ATOM   1273 O  O   . PHE A 1 210 ? 89.317  91.681  93.915  1.00 95.91 ? 198 PHE A O   1 
ATOM   1274 C  CB  . PHE A 1 210 ? 88.745  92.333  90.721  1.00 95.91 ? 198 PHE A CB  1 
ATOM   1275 C  CG  . PHE A 1 210 ? 90.025  91.556  90.684  1.00 95.91 ? 198 PHE A CG  1 
ATOM   1276 C  CD1 . PHE A 1 210 ? 90.009  90.181  90.587  1.00 95.91 ? 198 PHE A CD1 1 
ATOM   1277 C  CD2 . PHE A 1 210 ? 91.245  92.203  90.722  1.00 95.91 ? 198 PHE A CD2 1 
ATOM   1278 C  CE1 . PHE A 1 210 ? 91.184  89.461  90.547  1.00 95.91 ? 198 PHE A CE1 1 
ATOM   1279 C  CE2 . PHE A 1 210 ? 92.423  91.488  90.681  1.00 95.91 ? 198 PHE A CE2 1 
ATOM   1280 C  CZ  . PHE A 1 210 ? 92.394  90.115  90.595  1.00 95.91 ? 198 PHE A CZ  1 
ATOM   1281 N  N   . TRP A 1 211 ? 89.012  93.845  93.457  1.00 95.24 ? 199 TRP A N   1 
ATOM   1282 C  CA  . TRP A 1 211 ? 89.779  94.249  94.622  1.00 95.24 ? 199 TRP A CA  1 
ATOM   1283 C  C   . TRP A 1 211 ? 89.102  93.866  95.920  1.00 95.24 ? 199 TRP A C   1 
ATOM   1284 O  O   . TRP A 1 211 ? 89.728  93.297  96.810  1.00 95.24 ? 199 TRP A O   1 
ATOM   1285 C  CB  . TRP A 1 211 ? 89.985  95.759  94.591  1.00 95.24 ? 199 TRP A CB  1 
ATOM   1286 C  CG  . TRP A 1 211 ? 90.419  96.369  95.885  1.00 95.24 ? 199 TRP A CG  1 
ATOM   1287 C  CD1 . TRP A 1 211 ? 89.652  97.098  96.746  1.00 95.24 ? 199 TRP A CD1 1 
ATOM   1288 C  CD2 . TRP A 1 211 ? 91.727  96.321  96.459  1.00 95.24 ? 199 TRP A CD2 1 
ATOM   1289 N  NE1 . TRP A 1 211 ? 90.400  97.502  97.822  1.00 95.24 ? 199 TRP A NE1 1 
ATOM   1290 C  CE2 . TRP A 1 211 ? 91.678  97.037  97.670  1.00 95.24 ? 199 TRP A CE2 1 
ATOM   1291 C  CE3 . TRP A 1 211 ? 92.935  95.739  96.069  1.00 95.24 ? 199 TRP A CE3 1 
ATOM   1292 C  CZ2 . TRP A 1 211 ? 92.788  97.189  98.488  1.00 95.24 ? 199 TRP A CZ2 1 
ATOM   1293 C  CZ3 . TRP A 1 211 ? 94.032  95.887  96.885  1.00 95.24 ? 199 TRP A CZ3 1 
ATOM   1294 C  CH2 . TRP A 1 211 ? 93.953  96.605  98.080  1.00 95.24 ? 199 TRP A CH2 1 
ATOM   1295 N  N   . GLU A 1 212 ? 87.815  94.165  96.027  1.00 94.09 ? 200 GLU A N   1 
ATOM   1296 C  CA  . GLU A 1 212 ? 87.080  93.846  97.244  1.00 94.09 ? 200 GLU A CA  1 
ATOM   1297 C  C   . GLU A 1 212 ? 86.830  92.378  97.505  1.00 94.09 ? 200 GLU A C   1 
ATOM   1298 O  O   . GLU A 1 212 ? 86.957  91.939  98.630  1.00 94.09 ? 200 GLU A O   1 
ATOM   1299 C  CB  . GLU A 1 212 ? 85.765  94.622  97.307  1.00 94.09 ? 200 GLU A CB  1 
ATOM   1300 C  CG  . GLU A 1 212 ? 85.948  96.104  97.573  1.00 94.09 ? 200 GLU A CG  1 
ATOM   1301 C  CD  . GLU A 1 212 ? 84.631  96.846  97.621  1.00 94.09 ? 200 GLU A CD  1 
ATOM   1302 O  OE1 . GLU A 1 212 ? 84.644  98.063  97.903  1.00 94.09 ? 200 GLU A OE1 1 
ATOM   1303 O  OE2 . GLU A 1 212 ? 83.584  96.210  97.378  1.00 94.09 ? 200 GLU A OE2 1 
ATOM   1304 N  N   . ARG A 1 213 ? 86.457  91.619  96.481  1.00 95.75 ? 201 ARG A N   1 
ATOM   1305 C  CA  . ARG A 1 213 ? 86.092  90.221  96.698  1.00 95.75 ? 201 ARG A CA  1 
ATOM   1306 C  C   . ARG A 1 213 ? 87.104  89.150  96.309  1.00 95.75 ? 201 ARG A C   1 
ATOM   1307 O  O   . ARG A 1 213 ? 86.910  87.986  96.646  1.00 95.75 ? 201 ARG A O   1 
ATOM   1308 C  CB  . ARG A 1 213 ? 84.753  89.918  96.028  1.00 95.75 ? 201 ARG A CB  1 
ATOM   1309 C  CG  . ARG A 1 213 ? 83.662  90.920  96.354  1.00 95.75 ? 201 ARG A CG  1 
ATOM   1310 C  CD  . ARG A 1 213 ? 82.280  90.375  96.038  1.00 95.75 ? 201 ARG A CD  1 
ATOM   1311 N  NE  . ARG A 1 213 ? 81.763  89.519  97.104  1.00 95.75 ? 201 ARG A NE  1 
ATOM   1312 C  CZ  . ARG A 1 213 ? 81.784  88.189  97.087  1.00 95.75 ? 201 ARG A CZ  1 
ATOM   1313 N  NH1 . ARG A 1 213 ? 82.293  87.540  96.049  1.00 95.75 ? 201 ARG A NH1 1 
ATOM   1314 N  NH2 . ARG A 1 213 ? 81.288  87.506  98.110  1.00 95.75 ? 201 ARG A NH2 1 
ATOM   1315 N  N   . ASN A 1 214 ? 88.154  89.495  95.582  1.00 96.70 ? 202 ASN A N   1 
ATOM   1316 C  CA  . ASN A 1 214 ? 89.160  88.481  95.295  1.00 96.70 ? 202 ASN A CA  1 
ATOM   1317 C  C   . ASN A 1 214 ? 90.435  88.796  96.045  1.00 96.70 ? 202 ASN A C   1 
ATOM   1318 O  O   . ASN A 1 214 ? 90.887  88.002  96.865  1.00 96.70 ? 202 ASN A O   1 
ATOM   1319 C  CB  . ASN A 1 214 ? 89.423  88.324  93.801  1.00 96.70 ? 202 ASN A CB  1 
ATOM   1320 C  CG  . ASN A 1 214 ? 90.067  86.994  93.465  1.00 96.70 ? 202 ASN A CG  1 
ATOM   1321 O  OD1 . ASN A 1 214 ? 90.140  86.100  94.306  1.00 96.70 ? 202 ASN A OD1 1 
ATOM   1322 N  ND2 . ASN A 1 214 ? 90.528  86.851  92.233  1.00 96.70 ? 202 ASN A ND2 1 
ATOM   1323 N  N   . VAL A 1 215 ? 91.020  89.954  95.773  1.00 97.19 ? 203 VAL A N   1 
ATOM   1324 C  CA  . VAL A 1 215 ? 92.264  90.292  96.426  1.00 97.19 ? 203 VAL A CA  1 
ATOM   1325 C  C   . VAL A 1 215 ? 92.061  90.400  97.929  1.00 97.19 ? 203 VAL A C   1 
ATOM   1326 O  O   . VAL A 1 215 ? 92.829  89.842  98.687  1.00 97.19 ? 203 VAL A O   1 
ATOM   1327 C  CB  . VAL A 1 215 ? 92.841  91.611  95.897  1.00 97.19 ? 203 VAL A CB  1 
ATOM   1328 C  CG1 . VAL A 1 215 ? 94.224  91.864  96.479  1.00 97.19 ? 203 VAL A CG1 1 
ATOM   1329 C  CG2 . VAL A 1 215 ? 92.904  91.581  94.381  1.00 97.19 ? 203 VAL A CG2 1 
ATOM   1330 N  N   . LEU A 1 216 ? 91.004  91.069  98.370  1.00 96.16 ? 204 LEU A N   1 
ATOM   1331 C  CA  . LEU A 1 216 ? 90.820  91.265  99.807  1.00 96.16 ? 204 LEU A CA  1 
ATOM   1332 C  C   . LEU A 1 216 ? 89.862  90.309  100.489 1.00 96.16 ? 204 LEU A C   1 
ATOM   1333 O  O   . LEU A 1 216 ? 90.043  90.019  101.672 1.00 96.16 ? 204 LEU A O   1 
ATOM   1334 C  CB  . LEU A 1 216 ? 90.350  92.687  100.096 1.00 96.16 ? 204 LEU A CB  1 
ATOM   1335 C  CG  . LEU A 1 216 ? 91.320  93.849  99.946  1.00 96.16 ? 204 LEU A CG  1 
ATOM   1336 C  CD1 . LEU A 1 216 ? 90.614  95.088  100.464 1.00 96.16 ? 204 LEU A CD1 1 
ATOM   1337 C  CD2 . LEU A 1 216 ? 92.587  93.582  100.741 1.00 96.16 ? 204 LEU A CD2 1 
ATOM   1338 N  N   . SER A 1 217 ? 88.838  89.841  99.776  1.00 96.60 ? 205 SER A N   1 
ATOM   1339 C  CA  . SER A 1 217 ? 87.806  88.998  100.391 1.00 96.60 ? 205 SER A CA  1 
ATOM   1340 C  C   . SER A 1 217 ? 87.265  89.750  101.592 1.00 96.60 ? 205 SER A C   1 
ATOM   1341 O  O   . SER A 1 217 ? 87.054  89.160  102.645 1.00 96.60 ? 205 SER A O   1 
ATOM   1342 C  CB  . SER A 1 217 ? 88.334  87.614  100.768 1.00 96.60 ? 205 SER A CB  1 
ATOM   1343 O  OG  . SER A 1 217 ? 87.283  86.763  101.188 1.00 96.60 ? 205 SER A OG  1 
ATOM   1344 N  N   . LEU A 1 218 ? 87.038  91.051  101.439 1.00 94.70 ? 206 LEU A N   1 
ATOM   1345 C  CA  . LEU A 1 218 ? 86.597  91.888  102.557 1.00 94.70 ? 206 LEU A CA  1 
ATOM   1346 C  C   . LEU A 1 218 ? 85.491  91.303  103.416 1.00 94.70 ? 206 LEU A C   1 
ATOM   1347 O  O   . LEU A 1 218 ? 84.424  90.955  102.910 1.00 94.70 ? 206 LEU A O   1 
ATOM   1348 C  CB  . LEU A 1 218 ? 86.165  93.258  102.037 1.00 94.70 ? 206 LEU A CB  1 
ATOM   1349 C  CG  . LEU A 1 218 ? 86.237  94.408  103.035 1.00 94.70 ? 206 LEU A CG  1 
ATOM   1350 C  CD1 . LEU A 1 218 ? 87.653  94.520  103.568 1.00 94.70 ? 206 LEU A CD1 1 
ATOM   1351 C  CD2 . LEU A 1 218 ? 85.808  95.703  102.367 1.00 94.70 ? 206 LEU A CD2 1 
ATOM   1352 N  N   . SER A 1 219 ? 85.736  91.209  104.721 1.00 96.33 ? 207 SER A N   1 
ATOM   1353 C  CA  . SER A 1 219 ? 84.715  90.711  105.623 1.00 96.33 ? 207 SER A CA  1 
ATOM   1354 C  C   . SER A 1 219 ? 83.789  91.880  105.956 1.00 96.33 ? 207 SER A C   1 
ATOM   1355 O  O   . SER A 1 219 ? 84.082  93.009  105.572 1.00 96.33 ? 207 SER A O   1 
ATOM   1356 C  CB  . SER A 1 219 ? 85.369  90.200  106.900 1.00 96.33 ? 207 SER A CB  1 
ATOM   1357 O  OG  . SER A 1 219 ? 85.799  91.282  107.701 1.00 96.33 ? 207 SER A OG  1 
ATOM   1358 N  N   . PRO A 1 220 ? 82.657  91.635  106.664 1.00 95.06 ? 208 PRO A N   1 
ATOM   1359 C  CA  . PRO A 1 220 ? 81.856  92.832  106.961 1.00 95.06 ? 208 PRO A CA  1 
ATOM   1360 C  C   . PRO A 1 220 ? 82.584  93.779  107.903 1.00 95.06 ? 208 PRO A C   1 
ATOM   1361 O  O   . PRO A 1 220 ? 82.333  94.980  107.847 1.00 95.06 ? 208 PRO A O   1 
ATOM   1362 C  CB  . PRO A 1 220 ? 80.627  92.268  107.676 1.00 95.06 ? 208 PRO A CB  1 
ATOM   1363 C  CG  . PRO A 1 220 ? 80.510  90.875  107.181 1.00 95.06 ? 208 PRO A CG  1 
ATOM   1364 C  CD  . PRO A 1 220 ? 81.928  90.411  107.085 1.00 95.06 ? 208 PRO A CD  1 
ATOM   1365 N  N   . GLY A 1 221 ? 83.459  93.263  108.760 1.00 95.39 ? 209 GLY A N   1 
ATOM   1366 C  CA  . GLY A 1 221 ? 84.114  94.111  109.743 1.00 95.39 ? 209 GLY A CA  1 
ATOM   1367 C  C   . GLY A 1 221 ? 85.402  93.610  110.354 1.00 95.39 ? 209 GLY A C   1 
ATOM   1368 O  O   . GLY A 1 221 ? 85.760  92.455  110.168 1.00 95.39 ? 209 GLY A O   1 
ATOM   1369 N  N   . ILE A 1 222 ? 86.104  94.469  111.089 1.00 96.63 ? 210 ILE A N   1 
ATOM   1370 C  CA  . ILE A 1 222 ? 87.326  94.053  111.787 1.00 96.63 ? 210 ILE A CA  1 
ATOM   1371 C  C   . ILE A 1 222 ? 86.975  92.982  112.809 1.00 96.63 ? 210 ILE A C   1 
ATOM   1372 O  O   . ILE A 1 222 ? 87.760  92.068  113.055 1.00 96.63 ? 210 ILE A O   1 
ATOM   1373 C  CB  . ILE A 1 222 ? 88.073  95.244  112.437 1.00 96.63 ? 210 ILE A CB  1 
ATOM   1374 C  CG1 . ILE A 1 222 ? 89.396  94.795  113.063 1.00 96.63 ? 210 ILE A CG1 1 
ATOM   1375 C  CG2 . ILE A 1 222 ? 87.201  95.965  113.453 1.00 96.63 ? 210 ILE A CG2 1 
ATOM   1376 C  CD1 . ILE A 1 222 ? 90.165  95.916  113.724 1.00 96.63 ? 210 ILE A CD1 1 
ATOM   1377 N  N   . ASP A 1 223 ? 85.787  93.086  113.398 1.00 96.23 ? 211 ASP A N   1 
ATOM   1378 C  CA  . ASP A 1 223 ? 85.361  92.134  114.421 1.00 96.23 ? 211 ASP A CA  1 
ATOM   1379 C  C   . ASP A 1 223 ? 85.606  90.701  114.007 1.00 96.23 ? 211 ASP A C   1 
ATOM   1380 O  O   . ASP A 1 223 ? 86.113  89.904  114.793 1.00 96.23 ? 211 ASP A O   1 
ATOM   1381 C  CB  . ASP A 1 223 ? 83.881  92.331  114.731 1.00 96.23 ? 211 ASP A CB  1 
ATOM   1382 C  CG  . ASP A 1 223 ? 83.605  93.646  115.420 1.00 96.23 ? 211 ASP A CG  1 
ATOM   1383 O  OD1 . ASP A 1 223 ? 84.514  94.151  116.109 1.00 96.23 ? 211 ASP A OD1 1 
ATOM   1384 O  OD2 . ASP A 1 223 ? 82.480  94.169  115.282 1.00 96.23 ? 211 ASP A OD2 1 
ATOM   1385 N  N   . HIS A 1 224 ? 85.245  90.367  112.774 1.00 96.69 ? 212 HIS A N   1 
ATOM   1386 C  CA  . HIS A 1 224 ? 85.439  89.012  112.296 1.00 96.69 ? 212 HIS A CA  1 
ATOM   1387 C  C   . HIS A 1 224 ? 86.639  88.993  111.378 1.00 96.69 ? 212 HIS A C   1 
ATOM   1388 O  O   . HIS A 1 224 ? 86.601  89.561  110.291 1.00 96.69 ? 212 HIS A O   1 
ATOM   1389 C  CB  . HIS A 1 224 ? 84.205  88.559  111.526 1.00 96.69 ? 212 HIS A CB  1 
ATOM   1390 C  CG  . HIS A 1 224 ? 82.969  89.332  111.865 1.00 96.69 ? 212 HIS A CG  1 
ATOM   1391 N  ND1 . HIS A 1 224 ? 82.199  89.054  112.974 1.00 96.69 ? 212 HIS A ND1 1 
ATOM   1392 C  CD2 . HIS A 1 224 ? 82.373  90.376  111.244 1.00 96.69 ? 212 HIS A CD2 1 
ATOM   1393 C  CE1 . HIS A 1 224 ? 81.181  89.895  113.020 1.00 96.69 ? 212 HIS A CE1 1 
ATOM   1394 N  NE2 . HIS A 1 224 ? 81.263  90.707  111.983 1.00 96.69 ? 212 HIS A NE2 1 
ATOM   1395 N  N   . PRO A 1 225 ? 87.710  88.320  111.799 1.00 95.40 ? 213 PRO A N   1 
ATOM   1396 C  CA  . PRO A 1 225 ? 88.907  88.365  110.965 1.00 95.40 ? 213 PRO A CA  1 
ATOM   1397 C  C   . PRO A 1 225 ? 88.738  87.426  109.790 1.00 95.40 ? 213 PRO A C   1 
ATOM   1398 O  O   . PRO A 1 225 ? 89.226  87.717  108.706 1.00 95.40 ? 213 PRO A O   1 
ATOM   1399 C  CB  . PRO A 1 225 ? 90.013  87.860  111.897 1.00 95.40 ? 213 PRO A CB  1 
ATOM   1400 C  CG  . PRO A 1 225 ? 89.431  87.885  113.275 1.00 95.40 ? 213 PRO A CG  1 
ATOM   1401 C  CD  . PRO A 1 225 ? 87.961  87.672  113.094 1.00 95.40 ? 213 PRO A CD  1 
ATOM   1402 N  N   . GLY A 1 226 ? 88.055  86.307  110.000 1.00 96.80 ? 214 GLY A N   1 
ATOM   1403 C  CA  . GLY A 1 226 ? 87.829  85.356  108.930 1.00 96.80 ? 214 GLY A CA  1 
ATOM   1404 C  C   . GLY A 1 226 ? 89.058  84.497  108.721 1.00 96.80 ? 214 GLY A C   1 
ATOM   1405 O  O   . GLY A 1 226 ? 90.073  84.683  109.389 1.00 96.80 ? 214 GLY A O   1 
ATOM   1406 N  N   . SER A 1 227 ? 88.977  83.548  107.798 1.00 97.35 ? 215 SER A N   1 
ATOM   1407 C  CA  . SER A 1 227 ? 90.105  82.669  107.531 1.00 97.35 ? 215 SER A CA  1 
ATOM   1408 C  C   . SER A 1 227 ? 91.267  83.415  106.910 1.00 97.35 ? 215 SER A C   1 
ATOM   1409 O  O   . SER A 1 227 ? 91.067  84.304  106.091 1.00 97.35 ? 215 SER A O   1 
ATOM   1410 C  CB  . SER A 1 227 ? 89.679  81.532  106.606 1.00 97.35 ? 215 SER A CB  1 
ATOM   1411 O  OG  . SER A 1 227 ? 90.785  80.717  106.263 1.00 97.35 ? 215 SER A OG  1 
ATOM   1412 N  N   . LEU A 1 228 ? 92.483  83.092  107.332 1.00 98.02 ? 216 LEU A N   1 
ATOM   1413 C  CA  . LEU A 1 228 ? 93.658  83.721  106.753 1.00 98.02 ? 216 LEU A CA  1 
ATOM   1414 C  C   . LEU A 1 228 ? 93.702  83.316  105.295 1.00 98.02 ? 216 LEU A C   1 
ATOM   1415 O  O   . LEU A 1 228 ? 93.556  82.139  104.975 1.00 98.02 ? 216 LEU A O   1 
ATOM   1416 C  CB  . LEU A 1 228 ? 94.916  83.243  107.470 1.00 98.02 ? 216 LEU A CB  1 
ATOM   1417 C  CG  . LEU A 1 228 ? 96.273  83.728  106.968 1.00 98.02 ? 216 LEU A CG  1 
ATOM   1418 C  CD1 . LEU A 1 228 ? 96.388  85.232  107.132 1.00 98.02 ? 216 LEU A CD1 1 
ATOM   1419 C  CD2 . LEU A 1 228 ? 97.382  83.020  107.728 1.00 98.02 ? 216 LEU A CD2 1 
ATOM   1420 N  N   . LYS A 1 229 ? 93.899  84.276  104.400 1.00 97.89 ? 217 LYS A N   1 
ATOM   1421 C  CA  . LYS A 1 229 ? 93.878  83.944  102.990 1.00 97.89 ? 217 LYS A CA  1 
ATOM   1422 C  C   . LYS A 1 229 ? 95.226  83.370  102.648 1.00 97.89 ? 217 LYS A C   1 
ATOM   1423 O  O   . LYS A 1 229 ? 96.240  84.051  102.755 1.00 97.89 ? 217 LYS A O   1 
ATOM   1424 C  CB  . LYS A 1 229 ? 93.611  85.182  102.144 1.00 97.89 ? 217 LYS A CB  1 
ATOM   1425 C  CG  . LYS A 1 229 ? 92.239  85.792  102.345 1.00 97.89 ? 217 LYS A CG  1 
ATOM   1426 C  CD  . LYS A 1 229 ? 92.040  86.964  101.404 1.00 97.89 ? 217 LYS A CD  1 
ATOM   1427 C  CE  . LYS A 1 229 ? 92.249  86.541  99.960  1.00 97.89 ? 217 LYS A CE  1 
ATOM   1428 N  NZ  . LYS A 1 229 ? 91.264  85.515  99.518  1.00 97.89 ? 217 LYS A NZ  1 
ATOM   1429 N  N   . TRP A 1 230 ? 95.241  82.113  102.230 1.00 97.91 ? 218 TRP A N   1 
ATOM   1430 C  CA  . TRP A 1 230 ? 96.500  81.453  101.924 1.00 97.91 ? 218 TRP A CA  1 
ATOM   1431 C  C   . TRP A 1 230 ? 97.229  82.082  100.750 1.00 97.91 ? 218 TRP A C   1 
ATOM   1432 O  O   . TRP A 1 230 ? 98.449  82.225  100.781 1.00 97.91 ? 218 TRP A O   1 
ATOM   1433 C  CB  . TRP A 1 230 ? 96.281  79.952  101.697 1.00 97.91 ? 218 TRP A CB  1 
ATOM   1434 C  CG  . TRP A 1 230 ? 95.391  79.623  100.538 1.00 97.91 ? 218 TRP A CG  1 
ATOM   1435 C  CD1 . TRP A 1 230 ? 94.027  79.618  100.525 1.00 97.91 ? 218 TRP A CD1 1 
ATOM   1436 C  CD2 . TRP A 1 230 ? 95.805  79.239  99.222  1.00 97.91 ? 218 TRP A CD2 1 
ATOM   1437 N  NE1 . TRP A 1 230 ? 93.567  79.262  99.282  1.00 97.91 ? 218 TRP A NE1 1 
ATOM   1438 C  CE2 . TRP A 1 230 ? 94.639  79.025  98.463  1.00 97.91 ? 218 TRP A CE2 1 
ATOM   1439 C  CE3 . TRP A 1 230 ? 97.050  79.062  98.610  1.00 97.91 ? 218 TRP A CE3 1 
ATOM   1440 C  CZ2 . TRP A 1 230 ? 94.680  78.641  97.126  1.00 97.91 ? 218 TRP A CZ2 1 
ATOM   1441 C  CZ3 . TRP A 1 230 ? 97.088  78.682  97.283  1.00 97.91 ? 218 TRP A CZ3 1 
ATOM   1442 C  CH2 . TRP A 1 230 ? 95.911  78.474  96.556  1.00 97.91 ? 218 TRP A CH2 1 
ATOM   1443 N  N   . ASP A 1 231 ? 96.494  82.458  99.710  1.00 97.79 ? 219 ASP A N   1 
ATOM   1444 C  CA  . ASP A 1 231 ? 97.141  82.992  98.523  1.00 97.79 ? 219 ASP A CA  1 
ATOM   1445 C  C   . ASP A 1 231 ? 97.874  84.276  98.826  1.00 97.79 ? 219 ASP A C   1 
ATOM   1446 O  O   . ASP A 1 231 ? 99.020  84.448  98.423  1.00 97.79 ? 219 ASP A O   1 
ATOM   1447 C  CB  . ASP A 1 231 ? 96.097  83.226  97.434  1.00 97.79 ? 219 ASP A CB  1 
ATOM   1448 C  CG  . ASP A 1 231 ? 95.036  84.223  97.847  1.00 97.79 ? 219 ASP A CG  1 
ATOM   1449 O  OD1 . ASP A 1 231 ? 95.066  84.678  99.010  1.00 97.79 ? 219 ASP A OD1 1 
ATOM   1450 O  OD2 . ASP A 1 231 ? 94.172  84.553  97.010  1.00 97.79 ? 219 ASP A OD2 1 
ATOM   1451 N  N   . LEU A 1 232 ? 97.232  85.173  99.557  1.00 98.34 ? 220 LEU A N   1 
ATOM   1452 C  CA  . LEU A 1 232 ? 97.885  86.412  99.952  1.00 98.34 ? 220 LEU A CA  1 
ATOM   1453 C  C   . LEU A 1 232 ? 99.041  86.168  100.911 1.00 98.34 ? 220 LEU A C   1 
ATOM   1454 O  O   . LEU A 1 232 ? 100.068 86.834  100.827 1.00 98.34 ? 220 LEU A O   1 
ATOM   1455 C  CB  . LEU A 1 232 ? 96.875  87.390  100.531 1.00 98.34 ? 220 LEU A CB  1 
ATOM   1456 C  CG  . LEU A 1 232 ? 96.176  88.314  99.538  1.00 98.34 ? 220 LEU A CG  1 
ATOM   1457 C  CD1 . LEU A 1 232 ? 95.276  89.277  100.292 1.00 98.34 ? 220 LEU A CD1 1 
ATOM   1458 C  CD2 . LEU A 1 232 ? 97.218  89.085  98.745  1.00 98.34 ? 220 LEU A CD2 1 
ATOM   1459 N  N   . ALA A 1 233 ? 98.858  85.237  101.846 1.00 98.67 ? 221 ALA A N   1 
ATOM   1460 C  CA  . ALA A 1 233 ? 99.902  84.938  102.824 1.00 98.67 ? 221 ALA A CA  1 
ATOM   1461 C  C   . ALA A 1 233 ? 101.137 84.413  102.127 1.00 98.67 ? 221 ALA A C   1 
ATOM   1462 O  O   . ALA A 1 233 ? 102.253 84.765  102.492 1.00 98.67 ? 221 ALA A O   1 
ATOM   1463 C  CB  . ALA A 1 233 ? 99.407  83.938  103.848 1.00 98.67 ? 221 ALA A CB  1 
ATOM   1464 N  N   . LEU A 1 234 ? 100.947 83.562  101.128 1.00 98.70 ? 222 LEU A N   1 
ATOM   1465 C  CA  . LEU A 1 234 ? 102.082 83.072  100.358 1.00 98.70 ? 222 LEU A CA  1 
ATOM   1466 C  C   . LEU A 1 234 ? 102.753 84.221  99.632  1.00 98.70 ? 222 LEU A C   1 
ATOM   1467 O  O   . LEU A 1 234 ? 103.977 84.275  99.551  1.00 98.70 ? 222 LEU A O   1 
ATOM   1468 C  CB  . LEU A 1 234 ? 101.647 81.994  99.371  1.00 98.70 ? 222 LEU A CB  1 
ATOM   1469 C  CG  . LEU A 1 234 ? 101.264 80.658  100.005 1.00 98.70 ? 222 LEU A CG  1 
ATOM   1470 C  CD1 . LEU A 1 234 ? 100.811 79.669  98.944  1.00 98.70 ? 222 LEU A CD1 1 
ATOM   1471 C  CD2 . LEU A 1 234 ? 102.427 80.100  100.809 1.00 98.70 ? 222 LEU A CD2 1 
ATOM   1472 N  N   . CYS A 1 235 ? 101.963 85.156  99.117  1.00 98.77 ? 223 CYS A N   1 
ATOM   1473 C  CA  . CYS A 1 235 ? 102.541 86.324  98.467  1.00 98.77 ? 223 CYS A CA  1 
ATOM   1474 C  C   . CYS A 1 235 ? 103.302 87.158  99.482  1.00 98.77 ? 223 CYS A C   1 
ATOM   1475 O  O   . CYS A 1 235 ? 104.383 87.642  99.186  1.00 98.77 ? 223 CYS A O   1 
ATOM   1476 C  CB  . CYS A 1 235 ? 101.469 87.157  97.775  1.00 98.77 ? 223 CYS A CB  1 
ATOM   1477 S  SG  . CYS A 1 235 ? 100.737 86.348  96.337  1.00 98.77 ? 223 CYS A SG  1 
ATOM   1478 N  N   . LEU A 1 236 ? 102.749 87.320  100.681 1.00 98.81 ? 224 LEU A N   1 
ATOM   1479 C  CA  . LEU A 1 236 ? 103.419 88.089  101.728 1.00 98.81 ? 224 LEU A CA  1 
ATOM   1480 C  C   . LEU A 1 236 ? 104.741 87.439  102.072 1.00 98.81 ? 224 LEU A C   1 
ATOM   1481 O  O   . LEU A 1 236 ? 105.745 88.119  102.261 1.00 98.81 ? 224 LEU A O   1 
ATOM   1482 C  CB  . LEU A 1 236 ? 102.544 88.194  102.975 1.00 98.81 ? 224 LEU A CB  1 
ATOM   1483 C  CG  . LEU A 1 236 ? 103.053 89.072  104.117 1.00 98.81 ? 224 LEU A CG  1 
ATOM   1484 C  CD1 . LEU A 1 236 ? 103.270 90.490  103.624 1.00 98.81 ? 224 LEU A CD1 1 
ATOM   1485 C  CD2 . LEU A 1 236 ? 102.088 89.053  105.291 1.00 98.81 ? 224 LEU A CD2 1 
ATOM   1486 N  N   . LEU A 1 237 ? 104.753 86.114  102.130 1.00 98.75 ? 225 LEU A N   1 
ATOM   1487 C  CA  . LEU A 1 237 ? 105.980 85.400  102.437 1.00 98.75 ? 225 LEU A CA  1 
ATOM   1488 C  C   . LEU A 1 237 ? 107.000 85.668  101.359 1.00 98.75 ? 225 LEU A C   1 
ATOM   1489 O  O   . LEU A 1 237 ? 108.170 85.867  101.648 1.00 98.75 ? 225 LEU A O   1 
ATOM   1490 C  CB  . LEU A 1 237 ? 105.716 83.900  102.536 1.00 98.75 ? 225 LEU A CB  1 
ATOM   1491 C  CG  . LEU A 1 237 ? 106.863 83.023  103.031 1.00 98.75 ? 225 LEU A CG  1 
ATOM   1492 C  CD1 . LEU A 1 237 ? 107.282 83.437  104.433 1.00 98.75 ? 225 LEU A CD1 1 
ATOM   1493 C  CD2 . LEU A 1 237 ? 106.448 81.561  103.003 1.00 98.75 ? 225 LEU A CD2 1 
ATOM   1494 N  N   . LEU A 1 238 ? 106.557 85.682  100.110 1.00 98.73 ? 226 LEU A N   1 
ATOM   1495 C  CA  . LEU A 1 238 ? 107.473 85.909  99.007  1.00 98.73 ? 226 LEU A CA  1 
ATOM   1496 C  C   . LEU A 1 238 ? 108.105 87.294  99.094  1.00 98.73 ? 226 LEU A C   1 
ATOM   1497 O  O   . LEU A 1 238 ? 109.311 87.432  98.912  1.00 98.73 ? 226 LEU A O   1 
ATOM   1498 C  CB  . LEU A 1 238 ? 106.749 85.725  97.671  1.00 98.73 ? 226 LEU A CB  1 
ATOM   1499 C  CG  . LEU A 1 238 ? 107.554 85.633  96.373  1.00 98.73 ? 226 LEU A CG  1 
ATOM   1500 C  CD1 . LEU A 1 238 ? 106.922 84.613  95.440  1.00 98.73 ? 226 LEU A CD1 1 
ATOM   1501 C  CD2 . LEU A 1 238 ? 107.684 86.984  95.685  1.00 98.73 ? 226 LEU A CD2 1 
ATOM   1502 N  N   . VAL A 1 239 ? 107.310 88.315  99.403  1.00 98.60 ? 227 VAL A N   1 
ATOM   1503 C  CA  . VAL A 1 239 ? 107.862 89.656  99.540  1.00 98.60 ? 227 VAL A CA  1 
ATOM   1504 C  C   . VAL A 1 239 ? 108.836 89.710  100.703 1.00 98.60 ? 227 VAL A C   1 
ATOM   1505 O  O   . VAL A 1 239 ? 109.904 90.307  100.597 1.00 98.60 ? 227 VAL A O   1 
ATOM   1506 C  CB  . VAL A 1 239 ? 106.779 90.729  99.717  1.00 98.60 ? 227 VAL A CB  1 
ATOM   1507 C  CG1 . VAL A 1 239 ? 107.352 92.094  99.385  1.00 98.60 ? 227 VAL A CG1 1 
ATOM   1508 C  CG2 . VAL A 1 239 ? 105.619 90.462  98.784  1.00 98.60 ? 227 VAL A CG2 1 
ATOM   1509 N  N   . TRP A 1 240 ? 108.484 89.073  101.811 1.00 98.53 ? 228 TRP A N   1 
ATOM   1510 C  CA  . TRP A 1 240 ? 109.388 89.031  102.953 1.00 98.53 ? 228 TRP A CA  1 
ATOM   1511 C  C   . TRP A 1 240 ? 110.673 88.285  102.654 1.00 98.53 ? 228 TRP A C   1 
ATOM   1512 O  O   . TRP A 1 240 ? 111.736 88.686  103.100 1.00 98.53 ? 228 TRP A O   1 
ATOM   1513 C  CB  . TRP A 1 240 ? 108.710 88.447  104.190 1.00 98.53 ? 228 TRP A CB  1 
ATOM   1514 C  CG  . TRP A 1 240 ? 108.003 89.474  105.006 1.00 98.53 ? 228 TRP A CG  1 
ATOM   1515 C  CD1 . TRP A 1 240 ? 106.674 89.517  105.290 1.00 98.53 ? 228 TRP A CD1 1 
ATOM   1516 C  CD2 . TRP A 1 240 ? 108.587 90.621  105.635 1.00 98.53 ? 228 TRP A CD2 1 
ATOM   1517 N  NE1 . TRP A 1 240 ? 106.392 90.612  106.066 1.00 98.53 ? 228 TRP A NE1 1 
ATOM   1518 C  CE2 . TRP A 1 240 ? 107.550 91.308  106.291 1.00 98.53 ? 228 TRP A CE2 1 
ATOM   1519 C  CE3 . TRP A 1 240 ? 109.886 91.132  105.713 1.00 98.53 ? 228 TRP A CE3 1 
ATOM   1520 C  CZ2 . TRP A 1 240 ? 107.770 92.479  107.007 1.00 98.53 ? 228 TRP A CZ2 1 
ATOM   1521 C  CZ3 . TRP A 1 240 ? 110.101 92.293  106.425 1.00 98.53 ? 228 TRP A CZ3 1 
ATOM   1522 C  CH2 . TRP A 1 240 ? 109.050 92.953  107.064 1.00 98.53 ? 228 TRP A CH2 1 
ATOM   1523 N  N   . LEU A 1 241 ? 110.571 87.199  101.900 1.00 98.33 ? 229 LEU A N   1 
ATOM   1524 C  CA  . LEU A 1 241 ? 111.747 86.416  101.561 1.00 98.33 ? 229 LEU A CA  1 
ATOM   1525 C  C   . LEU A 1 241 ? 112.682 87.263  100.721 1.00 98.33 ? 229 LEU A C   1 
ATOM   1526 O  O   . LEU A 1 241 ? 113.887 87.266  100.945 1.00 98.33 ? 229 LEU A O   1 
ATOM   1527 C  CB  . LEU A 1 241 ? 111.355 85.154  100.804 1.00 98.33 ? 229 LEU A CB  1 
ATOM   1528 C  CG  . LEU A 1 241 ? 111.975 83.861  101.323 1.00 98.33 ? 229 LEU A CG  1 
ATOM   1529 C  CD1 . LEU A 1 241 ? 111.671 83.690  102.802 1.00 98.33 ? 229 LEU A CD1 1 
ATOM   1530 C  CD2 . LEU A 1 241 ? 111.466 82.674  100.523 1.00 98.33 ? 229 LEU A CD2 1 
ATOM   1531 N  N   . VAL A 1 242 ? 112.128 87.994  99.762  1.00 97.68 ? 230 VAL A N   1 
ATOM   1532 C  CA  . VAL A 1 242 ? 112.955 88.852  98.938  1.00 97.68 ? 230 VAL A CA  1 
ATOM   1533 C  C   . VAL A 1 242 ? 113.618 89.878  99.833  1.00 97.68 ? 230 VAL A C   1 
ATOM   1534 O  O   . VAL A 1 242 ? 114.820 90.112  99.736  1.00 97.68 ? 230 VAL A O   1 
ATOM   1535 C  CB  . VAL A 1 242 ? 112.124 89.580  97.866  1.00 97.68 ? 230 VAL A CB  1 
ATOM   1536 C  CG1 . VAL A 1 242 ? 112.947 90.657  97.175  1.00 97.68 ? 230 VAL A CG1 1 
ATOM   1537 C  CG2 . VAL A 1 242 ? 111.587 88.589  96.847  1.00 97.68 ? 230 VAL A CG2 1 
ATOM   1538 N  N   . CYS A 1 243 ? 112.850 90.452  100.752 1.00 97.47 ? 231 CYS A N   1 
ATOM   1539 C  CA  . CYS A 1 243 ? 113.403 91.468  101.627 1.00 97.47 ? 231 CYS A CA  1 
ATOM   1540 C  C   . CYS A 1 243 ? 114.500 90.908  102.511 1.00 97.47 ? 231 CYS A C   1 
ATOM   1541 O  O   . CYS A 1 243 ? 115.574 91.488  102.606 1.00 97.47 ? 231 CYS A O   1 
ATOM   1542 C  CB  . CYS A 1 243 ? 112.304 92.081  102.492 1.00 97.47 ? 231 CYS A CB  1 
ATOM   1543 S  SG  . CYS A 1 243 ? 112.896 93.285  103.698 1.00 97.47 ? 231 CYS A SG  1 
ATOM   1544 N  N   . PHE A 1 244 ? 114.260 89.751  103.111 1.00 97.02 ? 232 PHE A N   1 
ATOM   1545 C  CA  . PHE A 1 244 ? 115.244 89.192  104.018 1.00 97.02 ? 232 PHE A CA  1 
ATOM   1546 C  C   . PHE A 1 244 ? 116.524 88.849  103.285 1.00 97.02 ? 232 PHE A C   1 
ATOM   1547 O  O   . PHE A 1 244 ? 117.611 89.184  103.740 1.00 97.02 ? 232 PHE A O   1 
ATOM   1548 C  CB  . PHE A 1 244 ? 114.679 87.950  104.713 1.00 97.02 ? 232 PHE A CB  1 
ATOM   1549 C  CG  . PHE A 1 244 ? 115.727 87.030  105.267 1.00 97.02 ? 232 PHE A CG  1 
ATOM   1550 C  CD1 . PHE A 1 244 ? 116.515 87.416  106.339 1.00 97.02 ? 232 PHE A CD1 1 
ATOM   1551 C  CD2 . PHE A 1 244 ? 115.914 85.770  104.725 1.00 97.02 ? 232 PHE A CD2 1 
ATOM   1552 C  CE1 . PHE A 1 244 ? 117.480 86.571  106.845 1.00 97.02 ? 232 PHE A CE1 1 
ATOM   1553 C  CE2 . PHE A 1 244 ? 116.875 84.918  105.230 1.00 97.02 ? 232 PHE A CE2 1 
ATOM   1554 C  CZ  . PHE A 1 244 ? 117.658 85.318  106.293 1.00 97.02 ? 232 PHE A CZ  1 
ATOM   1555 N  N   . PHE A 1 245 ? 116.396 88.202  102.135 1.00 95.43 ? 233 PHE A N   1 
ATOM   1556 C  CA  . PHE A 1 245 ? 117.578 87.803  101.386 1.00 95.43 ? 233 PHE A CA  1 
ATOM   1557 C  C   . PHE A 1 245 ? 118.372 88.978  100.841 1.00 95.43 ? 233 PHE A C   1 
ATOM   1558 O  O   . PHE A 1 245 ? 119.595 88.973  100.883 1.00 95.43 ? 233 PHE A O   1 
ATOM   1559 C  CB  . PHE A 1 245 ? 117.240 86.776  100.309 1.00 95.43 ? 233 PHE A CB  1 
ATOM   1560 C  CG  . PHE A 1 245 ? 117.109 85.382  100.843 1.00 95.43 ? 233 PHE A CG  1 
ATOM   1561 C  CD1 . PHE A 1 245 ? 118.216 84.719  101.344 1.00 95.43 ? 233 PHE A CD1 1 
ATOM   1562 C  CD2 . PHE A 1 245 ? 115.885 84.739  100.860 1.00 95.43 ? 233 PHE A CD2 1 
ATOM   1563 C  CE1 . PHE A 1 245 ? 118.106 83.437  101.846 1.00 95.43 ? 233 PHE A CE1 1 
ATOM   1564 C  CE2 . PHE A 1 245 ? 115.767 83.458  101.360 1.00 95.43 ? 233 PHE A CE2 1 
ATOM   1565 C  CZ  . PHE A 1 245 ? 116.879 82.805  101.853 1.00 95.43 ? 233 PHE A CZ  1 
ATOM   1566 N  N   . CYS A 1 246 ? 117.679 89.990  100.336 1.00 94.93 ? 234 CYS A N   1 
ATOM   1567 C  CA  . CYS A 1 246 ? 118.370 91.163  99.832  1.00 94.93 ? 234 CYS A CA  1 
ATOM   1568 C  C   . CYS A 1 246 ? 119.104 91.859  100.964 1.00 94.93 ? 234 CYS A C   1 
ATOM   1569 O  O   . CYS A 1 246 ? 120.239 92.293  100.796 1.00 94.93 ? 234 CYS A O   1 
ATOM   1570 C  CB  . CYS A 1 246 ? 117.396 92.121  99.153  1.00 94.93 ? 234 CYS A CB  1 
ATOM   1571 S  SG  . CYS A 1 246 ? 118.184 93.549  98.380  1.00 94.93 ? 234 CYS A SG  1 
ATOM   1572 N  N   . ILE A 1 247 ? 118.464 91.951  102.124 1.00 94.65 ? 235 ILE A N   1 
ATOM   1573 C  CA  . ILE A 1 247 ? 119.085 92.611  103.267 1.00 94.65 ? 235 ILE A CA  1 
ATOM   1574 C  C   . ILE A 1 247 ? 120.220 91.739  103.796 1.00 94.65 ? 235 ILE A C   1 
ATOM   1575 O  O   . ILE A 1 247 ? 121.232 92.253  104.272 1.00 94.65 ? 235 ILE A O   1 
ATOM   1576 C  CB  . ILE A 1 247 ? 118.035 92.956  104.344 1.00 94.65 ? 235 ILE A CB  1 
ATOM   1577 C  CG1 . ILE A 1 247 ? 117.114 94.059  103.829 1.00 94.65 ? 235 ILE A CG1 1 
ATOM   1578 C  CG2 . ILE A 1 247 ? 118.678 93.443  105.625 1.00 94.65 ? 235 ILE A CG2 1 
ATOM   1579 C  CD1 . ILE A 1 247 ? 117.859 95.296  103.385 1.00 94.65 ? 235 ILE A CD1 1 
ATOM   1580 N  N   . TRP A 1 248 ? 120.078 90.423  103.675 1.00 93.13 ? 236 TRP A N   1 
ATOM   1581 C  CA  . TRP A 1 248 ? 121.146 89.521  104.102 1.00 93.13 ? 236 TRP A CA  1 
ATOM   1582 C  C   . TRP A 1 248 ? 122.392 89.788  103.280 1.00 93.13 ? 236 TRP A C   1 
ATOM   1583 O  O   . TRP A 1 248 ? 123.469 90.009  103.832 1.00 93.13 ? 236 TRP A O   1 
ATOM   1584 C  CB  . TRP A 1 248 ? 120.701 88.075  103.892 1.00 93.13 ? 236 TRP A CB  1 
ATOM   1585 C  CG  . TRP A 1 248 ? 121.393 87.062  104.738 1.00 93.13 ? 236 TRP A CG  1 
ATOM   1586 C  CD1 . TRP A 1 248 ? 120.961 86.564  105.929 1.00 93.13 ? 236 TRP A CD1 1 
ATOM   1587 C  CD2 . TRP A 1 248 ? 122.629 86.398  104.450 1.00 93.13 ? 236 TRP A CD2 1 
ATOM   1588 N  NE1 . TRP A 1 248 ? 121.851 85.636  106.406 1.00 93.13 ? 236 TRP A NE1 1 
ATOM   1589 C  CE2 . TRP A 1 248 ? 122.887 85.518  105.517 1.00 93.13 ? 236 TRP A CE2 1 
ATOM   1590 C  CE3 . TRP A 1 248 ? 123.544 86.468  103.397 1.00 93.13 ? 236 TRP A CE3 1 
ATOM   1591 C  CZ2 . TRP A 1 248 ? 124.022 84.715  105.563 1.00 93.13 ? 236 TRP A CZ2 1 
ATOM   1592 C  CZ3 . TRP A 1 248 ? 124.670 85.670  103.444 1.00 93.13 ? 236 TRP A CZ3 1 
ATOM   1593 C  CH2 . TRP A 1 248 ? 124.900 84.805  104.519 1.00 93.13 ? 236 TRP A CH2 1 
ATOM   1594 N  N   . LYS A 1 249 ? 122.251 89.788  101.957 1.00 90.74 ? 237 LYS A N   1 
ATOM   1595 C  CA  . LYS A 1 249 ? 123.394 90.022  101.070 1.00 90.74 ? 237 LYS A CA  1 
ATOM   1596 C  C   . LYS A 1 249 ? 123.851 91.473  101.098 1.00 90.74 ? 237 LYS A C   1 
ATOM   1597 O  O   . LYS A 1 249 ? 124.927 91.796  100.598 1.00 90.74 ? 237 LYS A O   1 
ATOM   1598 C  CB  . LYS A 1 249 ? 123.044 89.643  99.630  1.00 90.74 ? 237 LYS A CB  1 
ATOM   1599 C  CG  . LYS A 1 249 ? 122.420 88.269  99.463  1.00 90.74 ? 237 LYS A CG  1 
ATOM   1600 C  CD  . LYS A 1 249 ? 123.377 87.151  99.832  1.00 90.74 ? 237 LYS A CD  1 
ATOM   1601 C  CE  . LYS A 1 249 ? 122.679 85.802  99.765  1.00 90.74 ? 237 LYS A CE  1 
ATOM   1602 N  NZ  . LYS A 1 249 ? 123.588 84.684  100.138 1.00 90.74 ? 237 LYS A NZ  1 
ATOM   1603 N  N   . GLY A 1 250 ? 123.031 92.359  101.649 1.00 89.91 ? 238 GLY A N   1 
ATOM   1604 C  CA  . GLY A 1 250 ? 123.385 93.766  101.710 1.00 89.91 ? 238 GLY A CA  1 
ATOM   1605 C  C   . GLY A 1 250 ? 122.895 94.565  100.523 1.00 89.91 ? 238 GLY A C   1 
ATOM   1606 O  O   . GLY A 1 250 ? 122.400 94.001  99.548  1.00 89.91 ? 238 GLY A O   1 
ATOM   1607 N  N   . VAL A 1 251 ? 123.041 95.883  100.589 1.00 90.14 ? 239 VAL A N   1 
ATOM   1608 C  CA  . VAL A 1 251 ? 122.572 96.751  99.508  1.00 90.14 ? 239 VAL A CA  1 
ATOM   1609 C  C   . VAL A 1 251 ? 123.627 96.980  98.430  1.00 90.14 ? 239 VAL A C   1 
ATOM   1610 O  O   . VAL A 1 251 ? 123.372 97.673  97.447  1.00 90.14 ? 239 VAL A O   1 
ATOM   1611 C  CB  . VAL A 1 251 ? 122.093 98.110  100.051 1.00 90.14 ? 239 VAL A CB  1 
ATOM   1612 C  CG1 . VAL A 1 251 ? 120.818 97.935  100.861 1.00 90.14 ? 239 VAL A CG1 1 
ATOM   1613 C  CG2 . VAL A 1 251 ? 123.182 98.762  100.891 1.00 90.14 ? 239 VAL A CG2 1 
ATOM   1614 N  N   . ARG A 1 252 ? 124.809 96.404  98.610  1.00 86.21 ? 240 ARG A N   1 
ATOM   1615 C  CA  . ARG A 1 252 ? 125.887 96.581  97.641  1.00 86.21 ? 240 ARG A CA  1 
ATOM   1616 C  C   . ARG A 1 252 ? 125.511 96.022  96.275  1.00 86.21 ? 240 ARG A C   1 
ATOM   1617 O  O   . ARG A 1 252 ? 125.821 96.625  95.248  1.00 86.21 ? 240 ARG A O   1 
ATOM   1618 C  CB  . ARG A 1 252 ? 127.165 95.910  98.145  1.00 86.21 ? 240 ARG A CB  1 
ATOM   1619 N  N   . SER A 1 253 ? 124.835 94.879  96.257  1.00 88.90 ? 241 SER A N   1 
ATOM   1620 C  CA  . SER A 1 253 ? 124.444 94.251  94.997  1.00 88.90 ? 241 SER A CA  1 
ATOM   1621 C  C   . SER A 1 253 ? 123.505 95.132  94.187  1.00 88.90 ? 241 SER A C   1 
ATOM   1622 O  O   . SER A 1 253 ? 123.617 95.204  92.963  1.00 88.90 ? 241 SER A O   1 
ATOM   1623 C  CB  . SER A 1 253 ? 123.775 92.906  95.277  1.00 88.90 ? 241 SER A CB  1 
ATOM   1624 O  OG  . SER A 1 253 ? 122.683 93.060  96.168  1.00 88.90 ? 241 SER A OG  1 
ATOM   1625 N  N   . THR A 1 254 ? 122.583 95.808  94.861  1.00 90.11 ? 242 THR A N   1 
ATOM   1626 C  CA  . THR A 1 254 ? 121.600 96.642  94.172  1.00 90.11 ? 242 THR A CA  1 
ATOM   1627 C  C   . THR A 1 254 ? 122.216 97.787  93.391  1.00 90.11 ? 242 THR A C   1 
ATOM   1628 O  O   . THR A 1 254 ? 121.754 98.087  92.294  1.00 90.11 ? 242 THR A O   1 
ATOM   1629 C  CB  . THR A 1 254 ? 120.558 97.210  95.154  1.00 90.11 ? 242 THR A CB  1 
ATOM   1630 O  OG1 . THR A 1 254 ? 121.141 98.270  95.922  1.00 90.11 ? 242 THR A OG1 1 
ATOM   1631 C  CG2 . THR A 1 254 ? 120.063 96.121  96.089  1.00 90.11 ? 242 THR A CG2 1 
ATOM   1632 N  N   . GLY A 1 255 ? 123.287 98.388  93.899  1.00 89.65 ? 243 GLY A N   1 
ATOM   1633 C  CA  . GLY A 1 255 ? 123.853 99.574  93.269  1.00 89.65 ? 243 GLY A CA  1 
ATOM   1634 C  C   . GLY A 1 255 ? 124.287 99.459  91.823  1.00 89.65 ? 243 GLY A C   1 
ATOM   1635 O  O   . GLY A 1 255 ? 124.146 100.418 91.064  1.00 89.65 ? 243 GLY A O   1 
ATOM   1636 N  N   . LYS A 1 256 ? 124.810 98.309  91.424  1.00 91.64 ? 244 LYS A N   1 
ATOM   1637 C  CA  . LYS A 1 256 ? 125.317 98.150  90.064  1.00 91.64 ? 244 LYS A CA  1 
ATOM   1638 C  C   . LYS A 1 256 ? 124.250 98.365  88.987  1.00 91.64 ? 244 LYS A C   1 
ATOM   1639 O  O   . LYS A 1 256 ? 124.539 98.940  87.941  1.00 91.64 ? 244 LYS A O   1 
ATOM   1640 C  CB  . LYS A 1 256 ? 125.924 96.757  89.897  1.00 91.64 ? 244 LYS A CB  1 
ATOM   1641 C  CG  . LYS A 1 256 ? 126.839 96.337  91.035  1.00 91.64 ? 244 LYS A CG  1 
ATOM   1642 C  CD  . LYS A 1 256 ? 128.066 97.229  91.125  1.00 91.64 ? 244 LYS A CD  1 
ATOM   1643 C  CE  . LYS A 1 256 ? 128.937 96.838  92.306  1.00 91.64 ? 244 LYS A CE  1 
ATOM   1644 N  NZ  . LYS A 1 256 ? 128.190 96.925  93.591  1.00 91.64 ? 244 LYS A NZ  1 
ATOM   1645 N  N   . VAL A 1 257 ? 123.030 97.894  89.223  1.00 93.46 ? 245 VAL A N   1 
ATOM   1646 C  CA  . VAL A 1 257 ? 121.973 98.010  88.217  1.00 93.46 ? 245 VAL A CA  1 
ATOM   1647 C  C   . VAL A 1 257 ? 120.952 99.106  88.555  1.00 93.46 ? 245 VAL A C   1 
ATOM   1648 O  O   . VAL A 1 257 ? 120.051 99.384  87.763  1.00 93.46 ? 245 VAL A O   1 
ATOM   1649 C  CB  . VAL A 1 257 ? 121.271 96.648  88.021  1.00 93.46 ? 245 VAL A CB  1 
ATOM   1650 C  CG1 . VAL A 1 257 ? 120.293 96.367  89.152  1.00 93.46 ? 245 VAL A CG1 1 
ATOM   1651 C  CG2 . VAL A 1 257 ? 120.602 96.548  86.656  1.00 93.46 ? 245 VAL A CG2 1 
ATOM   1652 N  N   . VAL A 1 258 ? 121.097 99.745  89.714  1.00 94.70 ? 246 VAL A N   1 
ATOM   1653 C  CA  . VAL A 1 258 ? 120.145 100.780 90.136  1.00 94.70 ? 246 VAL A CA  1 
ATOM   1654 C  C   . VAL A 1 258 ? 119.762 101.771 89.035  1.00 94.70 ? 246 VAL A C   1 
ATOM   1655 O  O   . VAL A 1 258 ? 118.595 102.133 88.912  1.00 94.70 ? 246 VAL A O   1 
ATOM   1656 C  CB  . VAL A 1 258 ? 120.594 101.508 91.428  1.00 94.70 ? 246 VAL A CB  1 
ATOM   1657 C  CG1 . VAL A 1 258 ? 119.998 102.901 91.509  1.00 94.70 ? 246 VAL A CG1 1 
ATOM   1658 C  CG2 . VAL A 1 258 ? 120.152 100.726 92.652  1.00 94.70 ? 246 VAL A CG2 1 
ATOM   1659 N  N   . TYR A 1 259 ? 120.716 102.178 88.211  1.00 95.23 ? 247 TYR A N   1 
ATOM   1660 C  CA  . TYR A 1 259 ? 120.452 103.163 87.180  1.00 95.23 ? 247 TYR A CA  1 
ATOM   1661 C  C   . TYR A 1 259 ? 119.217 102.796 86.365  1.00 95.23 ? 247 TYR A C   1 
ATOM   1662 O  O   . TYR A 1 259 ? 118.413 103.665 86.046  1.00 95.23 ? 247 TYR A O   1 
ATOM   1663 C  CB  . TYR A 1 259 ? 121.679 103.291 86.284  1.00 95.23 ? 247 TYR A CB  1 
ATOM   1664 C  CG  . TYR A 1 259 ? 122.971 103.295 87.071  1.00 95.23 ? 247 TYR A CG  1 
ATOM   1665 C  CD1 . TYR A 1 259 ? 123.374 104.423 87.772  1.00 95.23 ? 247 TYR A CD1 1 
ATOM   1666 C  CD2 . TYR A 1 259 ? 123.775 102.163 87.133  1.00 95.23 ? 247 TYR A CD2 1 
ATOM   1667 C  CE1 . TYR A 1 259 ? 124.548 104.428 88.501  1.00 95.23 ? 247 TYR A CE1 1 
ATOM   1668 C  CE2 . TYR A 1 259 ? 124.948 102.160 87.860  1.00 95.23 ? 247 TYR A CE2 1 
ATOM   1669 C  CZ  . TYR A 1 259 ? 125.330 103.295 88.542  1.00 95.23 ? 247 TYR A CZ  1 
ATOM   1670 O  OH  . TYR A 1 259 ? 126.499 103.297 89.266  1.00 95.23 ? 247 TYR A OH  1 
ATOM   1671 N  N   . PHE A 1 260 ? 119.059 101.510 86.068  1.00 94.33 ? 248 PHE A N   1 
ATOM   1672 C  CA  . PHE A 1 260 ? 117.879 101.056 85.341  1.00 94.33 ? 248 PHE A CA  1 
ATOM   1673 C  C   . PHE A 1 260 ? 116.698 100.918 86.282  1.00 94.33 ? 248 PHE A C   1 
ATOM   1674 O  O   . PHE A 1 260 ? 115.590 101.335 85.955  1.00 94.33 ? 248 PHE A O   1 
ATOM   1675 C  CB  . PHE A 1 260 ? 118.138 99.716  84.648  1.00 94.33 ? 248 PHE A CB  1 
ATOM   1676 C  CG  . PHE A 1 260 ? 116.884 99.006  84.216  1.00 94.33 ? 248 PHE A CG  1 
ATOM   1677 C  CD1 . PHE A 1 260 ? 116.134 99.481  83.152  1.00 94.33 ? 248 PHE A CD1 1 
ATOM   1678 C  CD2 . PHE A 1 260 ? 116.454 97.865  84.875  1.00 94.33 ? 248 PHE A CD2 1 
ATOM   1679 C  CE1 . PHE A 1 260 ? 114.978 98.836  82.758  1.00 94.33 ? 248 PHE A CE1 1 
ATOM   1680 C  CE2 . PHE A 1 260 ? 115.299 97.215  84.485  1.00 94.33 ? 248 PHE A CE2 1 
ATOM   1681 C  CZ  . PHE A 1 260 ? 114.560 97.700  83.424  1.00 94.33 ? 248 PHE A CZ  1 
ATOM   1682 N  N   . THR A 1 261 ? 116.918 100.324 87.448  1.00 95.12 ? 249 THR A N   1 
ATOM   1683 C  CA  . THR A 1 261 ? 115.797 100.091 88.344  1.00 95.12 ? 249 THR A CA  1 
ATOM   1684 C  C   . THR A 1 261 ? 115.154 101.385 88.799  1.00 95.12 ? 249 THR A C   1 
ATOM   1685 O  O   . THR A 1 261 ? 113.949 101.459 88.870  1.00 95.12 ? 249 THR A O   1 
ATOM   1686 C  CB  . THR A 1 261 ? 116.154 99.219  89.560  1.00 95.12 ? 249 THR A CB  1 
ATOM   1687 O  OG1 . THR A 1 261 ? 117.223 99.822  90.295  1.00 95.12 ? 249 THR A OG1 1 
ATOM   1688 C  CG2 . THR A 1 261 ? 116.561 97.830  89.109  1.00 95.12 ? 249 THR A CG2 1 
ATOM   1689 N  N   . ALA A 1 262 ? 115.933 102.410 89.109  1.00 94.25 ? 250 ALA A N   1 
ATOM   1690 C  CA  . ALA A 1 262 ? 115.320 103.686 89.454  1.00 94.25 ? 250 ALA A CA  1 
ATOM   1691 C  C   . ALA A 1 262 ? 114.557 104.250 88.268  1.00 94.25 ? 250 ALA A C   1 
ATOM   1692 O  O   . ALA A 1 262 ? 113.444 104.744 88.423  1.00 94.25 ? 250 ALA A O   1 
ATOM   1693 C  CB  . ALA A 1 262 ? 116.370 104.675 89.928  1.00 94.25 ? 250 ALA A CB  1 
ATOM   1694 N  N   . THR A 1 263 ? 115.139 104.157 87.080  1.00 94.12 ? 251 THR A N   1 
ATOM   1695 C  CA  . THR A 1 263 ? 114.508 104.697 85.878  1.00 94.12 ? 251 THR A CA  1 
ATOM   1696 C  C   . THR A 1 263 ? 113.193 104.028 85.497  1.00 94.12 ? 251 THR A C   1 
ATOM   1697 O  O   . THR A 1 263 ? 112.256 104.706 85.081  1.00 94.12 ? 251 THR A O   1 
ATOM   1698 C  CB  . THR A 1 263 ? 115.486 104.679 84.684  1.00 94.12 ? 251 THR A CB  1 
ATOM   1699 O  OG1 . THR A 1 263 ? 116.636 105.471 85.004  1.00 94.12 ? 251 THR A OG1 1 
ATOM   1700 C  CG2 . THR A 1 263 ? 114.844 105.241 83.425  1.00 94.12 ? 251 THR A CG2 1 
ATOM   1701 N  N   . PHE A 1 264 ? 113.087 102.713 85.662  1.00 93.43 ? 252 PHE A N   1 
ATOM   1702 C  CA  . PHE A 1 264 ? 111.879 102.027 85.192  1.00 93.43 ? 252 PHE A CA  1 
ATOM   1703 C  C   . PHE A 1 264 ? 110.598 102.531 85.851  1.00 93.43 ? 252 PHE A C   1 
ATOM   1704 O  O   . PHE A 1 264 ? 109.597 102.721 85.169  1.00 93.43 ? 252 PHE A O   1 
ATOM   1705 C  CB  . PHE A 1 264 ? 112.024 100.497 85.295  1.00 93.43 ? 252 PHE A CB  1 
ATOM   1706 C  CG  . PHE A 1 264 ? 110.796 99.735  84.879  1.00 93.43 ? 252 PHE A CG  1 
ATOM   1707 C  CD1 . PHE A 1 264 ? 110.549 99.472  83.544  1.00 93.43 ? 252 PHE A CD1 1 
ATOM   1708 C  CD2 . PHE A 1 264 ? 109.894 99.273  85.824  1.00 93.43 ? 252 PHE A CD2 1 
ATOM   1709 C  CE1 . PHE A 1 264 ? 109.424 98.770  83.160  1.00 93.43 ? 252 PHE A CE1 1 
ATOM   1710 C  CE2 . PHE A 1 264 ? 108.767 98.573  85.447  1.00 93.43 ? 252 PHE A CE2 1 
ATOM   1711 C  CZ  . PHE A 1 264 ? 108.533 98.319  84.113  1.00 93.43 ? 252 PHE A CZ  1 
ATOM   1712 N  N   . PRO A 1 265 ? 110.613 102.768 87.171  1.00 93.22 ? 253 PRO A N   1 
ATOM   1713 C  CA  . PRO A 1 265 ? 109.393 103.343 87.722  1.00 93.22 ? 253 PRO A CA  1 
ATOM   1714 C  C   . PRO A 1 265 ? 108.999 104.696 87.156  1.00 93.22 ? 253 PRO A C   1 
ATOM   1715 O  O   . PRO A 1 265 ? 107.826 104.911 86.874  1.00 93.22 ? 253 PRO A O   1 
ATOM   1716 C  CB  . PRO A 1 265 ? 109.761 103.515 89.179  1.00 93.22 ? 253 PRO A CB  1 
ATOM   1717 C  CG  . PRO A 1 265 ? 110.584 102.315 89.466  1.00 93.22 ? 253 PRO A CG  1 
ATOM   1718 C  CD  . PRO A 1 265 ? 111.243 101.913 88.181  1.00 93.22 ? 253 PRO A CD  1 
ATOM   1719 N  N   . PHE A 1 266 ? 109.956 105.591 86.981  1.00 93.24 ? 254 PHE A N   1 
ATOM   1720 C  CA  . PHE A 1 266 ? 109.641 106.891 86.435  1.00 93.24 ? 254 PHE A CA  1 
ATOM   1721 C  C   . PHE A 1 266 ? 109.115 106.726 85.026  1.00 93.24 ? 254 PHE A C   1 
ATOM   1722 O  O   . PHE A 1 266 ? 108.161 107.391 84.635  1.00 93.24 ? 254 PHE A O   1 
ATOM   1723 C  CB  . PHE A 1 266 ? 110.859 107.804 86.459  1.00 93.24 ? 254 PHE A CB  1 
ATOM   1724 C  CG  . PHE A 1 266 ? 111.455 107.974 87.825  1.00 93.24 ? 254 PHE A CG  1 
ATOM   1725 C  CD1 . PHE A 1 266 ? 110.644 108.208 88.923  1.00 93.24 ? 254 PHE A CD1 1 
ATOM   1726 C  CD2 . PHE A 1 266 ? 112.824 107.909 88.011  1.00 93.24 ? 254 PHE A CD2 1 
ATOM   1727 C  CE1 . PHE A 1 266 ? 111.187 108.363 90.182  1.00 93.24 ? 254 PHE A CE1 1 
ATOM   1728 C  CE2 . PHE A 1 266 ? 113.374 108.065 89.268  1.00 93.24 ? 254 PHE A CE2 1 
ATOM   1729 C  CZ  . PHE A 1 266 ? 112.554 108.291 90.356  1.00 93.24 ? 254 PHE A CZ  1 
ATOM   1730 N  N   . ALA A 1 267 ? 109.727 105.830 84.262  1.00 93.38 ? 255 ALA A N   1 
ATOM   1731 C  CA  . ALA A 1 267 ? 109.280 105.592 82.897  1.00 93.38 ? 255 ALA A CA  1 
ATOM   1732 C  C   . ALA A 1 267 ? 107.863 105.037 82.835  1.00 93.38 ? 255 ALA A C   1 
ATOM   1733 O  O   . ALA A 1 267 ? 107.060 105.477 82.016  1.00 93.38 ? 255 ALA A O   1 
ATOM   1734 C  CB  . ALA A 1 267 ? 110.242 104.657 82.189  1.00 93.38 ? 255 ALA A CB  1 
ATOM   1735 N  N   . MET A 1 268 ? 107.545 104.074 83.694  1.00 91.00 ? 256 MET A N   1 
ATOM   1736 C  CA  . MET A 1 268 ? 106.204 103.498 83.704  1.00 91.00 ? 256 MET A CA  1 
ATOM   1737 C  C   . MET A 1 268 ? 105.179 104.517 84.156  1.00 91.00 ? 256 MET A C   1 
ATOM   1738 O  O   . MET A 1 268 ? 104.075 104.572 83.622  1.00 91.00 ? 256 MET A O   1 
ATOM   1739 C  CB  . MET A 1 268 ? 106.128 102.259 84.591  1.00 91.00 ? 256 MET A CB  1 
ATOM   1740 C  CG  . MET A 1 268 ? 106.009 100.966 83.811  1.00 91.00 ? 256 MET A CG  1 
ATOM   1741 S  SD  . MET A 1 268 ? 104.845 101.110 82.444  1.00 91.00 ? 256 MET A SD  1 
ATOM   1742 C  CE  . MET A 1 268 ? 103.273 101.186 83.296  1.00 91.00 ? 256 MET A CE  1 
ATOM   1743 N  N   . LEU A 1 269 ? 105.544 105.335 85.132  1.00 92.25 ? 257 LEU A N   1 
ATOM   1744 C  CA  . LEU A 1 269 ? 104.627 106.344 85.634  1.00 92.25 ? 257 LEU A CA  1 
ATOM   1745 C  C   . LEU A 1 269 ? 104.309 107.305 84.508  1.00 92.25 ? 257 LEU A C   1 
ATOM   1746 O  O   . LEU A 1 269 ? 103.176 107.753 84.374  1.00 92.25 ? 257 LEU A O   1 
ATOM   1747 C  CB  . LEU A 1 269 ? 105.232 107.082 86.823  1.00 92.25 ? 257 LEU A CB  1 
ATOM   1748 C  CG  . LEU A 1 269 ? 104.264 107.838 87.731  1.00 92.25 ? 257 LEU A CG  1 
ATOM   1749 C  CD1 . LEU A 1 269 ? 103.210 106.887 88.276  1.00 92.25 ? 257 LEU A CD1 1 
ATOM   1750 C  CD2 . LEU A 1 269 ? 105.025 108.504 88.866  1.00 92.25 ? 257 LEU A CD2 1 
ATOM   1751 N  N   . LEU A 1 270 ? 105.307 107.623 83.693  1.00 94.10 ? 258 LEU A N   1 
ATOM   1752 C  CA  . LEU A 1 270 ? 105.095 108.527 82.575  1.00 94.10 ? 258 LEU A CA  1 
ATOM   1753 C  C   . LEU A 1 270 ? 104.091 107.957 81.577  1.00 94.10 ? 258 LEU A C   1 
ATOM   1754 O  O   . LEU A 1 270 ? 103.243 108.685 81.075  1.00 94.10 ? 258 LEU A O   1 
ATOM   1755 C  CB  . LEU A 1 270 ? 106.420 108.826 81.881  1.00 94.10 ? 258 LEU A CB  1 
ATOM   1756 C  CG  . LEU A 1 270 ? 106.438 109.903 80.795  1.00 94.10 ? 258 LEU A CG  1 
ATOM   1757 C  CD1 . LEU A 1 270 ? 107.773 110.631 80.791  1.00 94.10 ? 258 LEU A CD1 1 
ATOM   1758 C  CD2 . LEU A 1 270 ? 106.125 109.334 79.420  1.00 94.10 ? 258 LEU A CD2 1 
ATOM   1759 N  N   . VAL A 1 271 ? 104.172 106.660 81.295  1.00 91.86 ? 259 VAL A N   1 
ATOM   1760 C  CA  . VAL A 1 271 ? 103.224 106.040 80.373  1.00 91.86 ? 259 VAL A CA  1 
ATOM   1761 C  C   . VAL A 1 271 ? 101.811 106.132 80.924  1.00 91.86 ? 259 VAL A C   1 
ATOM   1762 O  O   . VAL A 1 271 ? 100.876 106.473 80.200  1.00 91.86 ? 259 VAL A O   1 
ATOM   1763 C  CB  . VAL A 1 271 ? 103.571 104.566 80.109  1.00 91.86 ? 259 VAL A CB  1 
ATOM   1764 C  CG1 . VAL A 1 271 ? 102.568 103.939 79.153  1.00 91.86 ? 259 VAL A CG1 1 
ATOM   1765 C  CG2 . VAL A 1 271 ? 104.978 104.449 79.552  1.00 91.86 ? 259 VAL A CG2 1 
ATOM   1766 N  N   . LEU A 1 272 ? 101.653 105.875 82.218  1.00 88.86 ? 260 LEU A N   1 
ATOM   1767 C  CA  . LEU A 1 272 ? 100.338 105.977 82.838  1.00 88.86 ? 260 LEU A CA  1 
ATOM   1768 C  C   . LEU A 1 272 ? 99.843  107.408 82.761  1.00 88.86 ? 260 LEU A C   1 
ATOM   1769 O  O   . LEU A 1 272 ? 98.668  107.646 82.504  1.00 88.86 ? 260 LEU A O   1 
ATOM   1770 C  CB  . LEU A 1 272 ? 100.392 105.532 84.296  1.00 88.86 ? 260 LEU A CB  1 
ATOM   1771 C  CG  . LEU A 1 272 ? 100.837 104.103 84.580  1.00 88.86 ? 260 LEU A CG  1 
ATOM   1772 C  CD1 . LEU A 1 272 ? 101.300 103.998 86.021  1.00 88.86 ? 260 LEU A CD1 1 
ATOM   1773 C  CD2 . LEU A 1 272 ? 99.724  103.111 84.281  1.00 88.86 ? 260 LEU A CD2 1 
ATOM   1774 N  N   . LEU A 1 273 ? 100.738 108.362 82.987  1.00 93.72 ? 261 LEU A N   1 
ATOM   1775 C  CA  . LEU A 1 273 ? 100.349 109.760 82.951  1.00 93.72 ? 261 LEU A CA  1 
ATOM   1776 C  C   . LEU A 1 273 ? 99.862  110.151 81.568  1.00 93.72 ? 261 LEU A C   1 
ATOM   1777 O  O   . LEU A 1 273 ? 98.833  110.804 81.435  1.00 93.72 ? 261 LEU A O   1 
ATOM   1778 C  CB  . LEU A 1 273 ? 101.527 110.645 83.349  1.00 93.72 ? 261 LEU A CB  1 
ATOM   1779 C  CG  . LEU A 1 273 ? 101.337 112.156 83.242  1.00 93.72 ? 261 LEU A CG  1 
ATOM   1780 C  CD1 . LEU A 1 273 ? 100.474 112.661 84.386  1.00 93.72 ? 261 LEU A CD1 1 
ATOM   1781 C  CD2 . LEU A 1 273 ? 102.685 112.856 83.234  1.00 93.72 ? 261 LEU A CD2 1 
ATOM   1782 N  N   . VAL A 1 274 ? 100.575 109.724 80.532  1.00 95.35 ? 262 VAL A N   1 
ATOM   1783 C  CA  . VAL A 1 274 ? 100.185 110.086 79.180  1.00 95.35 ? 262 VAL A CA  1 
ATOM   1784 C  C   . VAL A 1 274 ? 98.824  109.488 78.875  1.00 95.35 ? 262 VAL A C   1 
ATOM   1785 O  O   . VAL A 1 274 ? 97.943  110.167 78.346  1.00 95.35 ? 262 VAL A O   1 
ATOM   1786 C  CB  . VAL A 1 274 ? 101.218 109.618 78.142  1.00 95.35 ? 262 VAL A CB  1 
ATOM   1787 C  CG1 . VAL A 1 274 ? 100.696 109.818 76.727  1.00 95.35 ? 262 VAL A CG1 1 
ATOM   1788 C  CG2 . VAL A 1 274 ? 102.526 110.365 78.329  1.00 95.35 ? 262 VAL A CG2 1 
ATOM   1789 N  N   . ARG A 1 275 ? 98.632  108.233 79.270  1.00 89.46 ? 263 ARG A N   1 
ATOM   1790 C  CA  . ARG A 1 275 ? 97.366  107.545 79.017  1.00 89.46 ? 263 ARG A CA  1 
ATOM   1791 C  C   . ARG A 1 275 ? 96.157  108.223 79.656  1.00 89.46 ? 263 ARG A C   1 
ATOM   1792 O  O   . ARG A 1 275 ? 95.156  108.432 78.987  1.00 89.46 ? 263 ARG A O   1 
ATOM   1793 C  CB  . ARG A 1 275 ? 97.457  106.081 79.464  1.00 89.46 ? 263 ARG A CB  1 
ATOM   1794 C  CG  . ARG A 1 275 ? 96.247  105.241 79.099  1.00 89.46 ? 263 ARG A CG  1 
ATOM   1795 C  CD  . ARG A 1 275 ? 95.906  105.415 77.630  1.00 89.46 ? 263 ARG A CD  1 
ATOM   1796 N  NE  . ARG A 1 275 ? 94.597  104.867 77.301  1.00 89.46 ? 263 ARG A NE  1 
ATOM   1797 C  CZ  . ARG A 1 275 ? 93.941  105.147 76.182  1.00 89.46 ? 263 ARG A CZ  1 
ATOM   1798 N  NH1 . ARG A 1 275 ? 94.473  105.974 75.294  1.00 89.46 ? 263 ARG A NH1 1 
ATOM   1799 N  NH2 . ARG A 1 275 ? 92.755  104.604 75.948  1.00 89.46 ? 263 ARG A NH2 1 
ATOM   1800 N  N   . GLY A 1 276 ? 96.233  108.574 80.935  1.00 91.47 ? 264 GLY A N   1 
ATOM   1801 C  CA  . GLY A 1 276 ? 95.071  109.143 81.593  1.00 91.47 ? 264 GLY A CA  1 
ATOM   1802 C  C   . GLY A 1 276 ? 94.636  110.451 80.970  1.00 91.47 ? 264 GLY A C   1 
ATOM   1803 O  O   . GLY A 1 276 ? 93.437  110.673 80.731  1.00 91.47 ? 264 GLY A O   1 
ATOM   1804 N  N   . LEU A 1 277 ? 95.602  111.309 80.662  1.00 95.69 ? 265 LEU A N   1 
ATOM   1805 C  CA  . LEU A 1 277 ? 95.289  112.591 80.046  1.00 95.69 ? 265 LEU A CA  1 
ATOM   1806 C  C   . LEU A 1 277 ? 94.659  112.355 78.689  1.00 95.69 ? 265 LEU A C   1 
ATOM   1807 O  O   . LEU A 1 277 ? 93.710  113.039 78.314  1.00 95.69 ? 265 LEU A O   1 
ATOM   1808 C  CB  . LEU A 1 277 ? 96.550  113.443 79.924  1.00 95.69 ? 265 LEU A CB  1 
ATOM   1809 C  CG  . LEU A 1 277 ? 97.268  113.717 81.246  1.00 95.69 ? 265 LEU A CG  1 
ATOM   1810 C  CD1 . LEU A 1 277 ? 98.585  114.440 81.013  1.00 95.69 ? 265 LEU A CD1 1 
ATOM   1811 C  CD2 . LEU A 1 277 ? 96.380  114.491 82.208  1.00 95.69 ? 265 LEU A CD2 1 
ATOM   1812 N  N   . THR A 1 278 ? 95.177  111.387 77.946  1.00 94.52 ? 266 THR A N   1 
ATOM   1813 C  CA  . THR A 1 278 ? 94.588  111.037 76.660  1.00 94.52 ? 266 THR A CA  1 
ATOM   1814 C  C   . THR A 1 278 ? 93.175  110.512 76.871  1.00 94.52 ? 266 THR A C   1 
ATOM   1815 O  O   . THR A 1 278 ? 92.279  110.791 76.075  1.00 94.52 ? 266 THR A O   1 
ATOM   1816 C  CB  . THR A 1 278 ? 95.446  109.995 75.925  1.00 94.52 ? 266 THR A CB  1 
ATOM   1817 O  OG1 . THR A 1 278 ? 96.798  110.462 75.844  1.00 94.52 ? 266 THR A OG1 1 
ATOM   1818 C  CG2 . THR A 1 278 ? 94.921  109.747 74.518  1.00 94.52 ? 266 THR A CG2 1 
ATOM   1819 N  N   . LEU A 1 279 ? 92.961  109.769 77.954  1.00 91.74 ? 267 LEU A N   1 
ATOM   1820 C  CA  . LEU A 1 279 ? 91.653  109.172 78.208  1.00 91.74 ? 267 LEU A CA  1 
ATOM   1821 C  C   . LEU A 1 279 ? 90.582  110.231 78.292  1.00 91.74 ? 267 LEU A C   1 
ATOM   1822 O  O   . LEU A 1 279 ? 90.797  111.293 78.864  1.00 91.74 ? 267 LEU A O   1 
ATOM   1823 C  CB  . LEU A 1 279 ? 91.660  108.354 79.506  1.00 91.74 ? 267 LEU A CB  1 
ATOM   1824 C  CG  . LEU A 1 279 ? 92.211  106.931 79.473  1.00 91.74 ? 267 LEU A CG  1 
ATOM   1825 C  CD1 . LEU A 1 279 ? 92.397  106.399 80.885  1.00 91.74 ? 267 LEU A CD1 1 
ATOM   1826 C  CD2 . LEU A 1 279 ? 91.284  106.031 78.677  1.00 91.74 ? 267 LEU A CD2 1 
ATOM   1827 N  N   . PRO A 1 280 ? 89.371  109.969 77.721  1.00 92.79 ? 268 PRO A N   1 
ATOM   1828 C  CA  . PRO A 1 280 ? 88.398  111.064 77.845  1.00 92.79 ? 268 PRO A CA  1 
ATOM   1829 C  C   . PRO A 1 280 ? 87.942  111.293 79.276  1.00 92.79 ? 268 PRO A C   1 
ATOM   1830 O  O   . PRO A 1 280 ? 87.994  110.377 80.087  1.00 92.79 ? 268 PRO A O   1 
ATOM   1831 C  CB  . PRO A 1 280 ? 87.210  110.579 77.008  1.00 92.79 ? 268 PRO A CB  1 
ATOM   1832 C  CG  . PRO A 1 280 ? 87.769  109.551 76.091  1.00 92.79 ? 268 PRO A CG  1 
ATOM   1833 C  CD  . PRO A 1 280 ? 88.808  108.862 76.913  1.00 92.79 ? 268 PRO A CD  1 
ATOM   1834 N  N   . GLY A 1 281 ? 87.497  112.504 79.587  1.00 92.84 ? 269 GLY A N   1 
ATOM   1835 C  CA  . GLY A 1 281 ? 87.045  112.810 80.931  1.00 92.84 ? 269 GLY A CA  1 
ATOM   1836 C  C   . GLY A 1 281 ? 88.188  113.116 81.869  1.00 92.84 ? 269 GLY A C   1 
ATOM   1837 O  O   . GLY A 1 281 ? 87.980  113.290 83.065  1.00 92.84 ? 269 GLY A O   1 
ATOM   1838 N  N   . ALA A 1 282 ? 89.397  113.202 81.333  1.00 94.76 ? 270 ALA A N   1 
ATOM   1839 C  CA  . ALA A 1 282 ? 90.564  113.480 82.152  1.00 94.76 ? 270 ALA A CA  1 
ATOM   1840 C  C   . ALA A 1 282 ? 90.471  114.831 82.807  1.00 94.76 ? 270 ALA A C   1 
ATOM   1841 O  O   . ALA A 1 282 ? 90.846  114.981 83.963  1.00 94.76 ? 270 ALA A O   1 
ATOM   1842 C  CB  . ALA A 1 282 ? 91.813  113.419 81.306  1.00 94.76 ? 270 ALA A CB  1 
ATOM   1843 N  N   . GLY A 1 283 ? 89.950  115.818 82.091  1.00 95.31 ? 271 GLY A N   1 
ATOM   1844 C  CA  . GLY A 1 283 ? 89.919  117.171 82.615  1.00 95.31 ? 271 GLY A CA  1 
ATOM   1845 C  C   . GLY A 1 283 ? 89.138  117.344 83.896  1.00 95.31 ? 271 GLY A C   1 
ATOM   1846 O  O   . GLY A 1 283 ? 89.561  118.084 84.774  1.00 95.31 ? 271 GLY A O   1 
ATOM   1847 N  N   . ALA A 1 284 ? 88.005  116.666 84.013  1.00 94.19 ? 272 ALA A N   1 
ATOM   1848 C  CA  . ALA A 1 284 ? 87.217  116.750 85.230  1.00 94.19 ? 272 ALA A CA  1 
ATOM   1849 C  C   . ALA A 1 284 ? 88.016  116.225 86.408  1.00 94.19 ? 272 ALA A C   1 
ATOM   1850 O  O   . ALA A 1 284 ? 87.972  116.797 87.492  1.00 94.19 ? 272 ALA A O   1 
ATOM   1851 C  CB  . ALA A 1 284 ? 85.922  115.975 85.080  1.00 94.19 ? 272 ALA A CB  1 
ATOM   1852 N  N   . GLY A 1 285 ? 88.746  115.136 86.205  1.00 94.24 ? 273 GLY A N   1 
ATOM   1853 C  CA  . GLY A 1 285 ? 89.579  114.608 87.266  1.00 94.24 ? 273 GLY A CA  1 
ATOM   1854 C  C   . GLY A 1 285 ? 90.669  115.562 87.674  1.00 94.24 ? 273 GLY A C   1 
ATOM   1855 O  O   . GLY A 1 285 ? 90.909  115.757 88.861  1.00 94.24 ? 273 GLY A O   1 
ATOM   1856 N  N   . ILE A 1 286 ? 91.318  116.181 86.696  1.00 96.39 ? 274 ILE A N   1 
ATOM   1857 C  CA  . ILE A 1 286 ? 92.356  117.152 86.994  1.00 96.39 ? 274 ILE A CA  1 
ATOM   1858 C  C   . ILE A 1 286 ? 91.737  118.333 87.722  1.00 96.39 ? 274 ILE A C   1 
ATOM   1859 O  O   . ILE A 1 286 ? 92.314  118.850 88.665  1.00 96.39 ? 274 ILE A O   1 
ATOM   1860 C  CB  . ILE A 1 286 ? 93.054  117.641 85.718  1.00 96.39 ? 274 ILE A CB  1 
ATOM   1861 C  CG1 . ILE A 1 286 ? 93.565  116.460 84.901  1.00 96.39 ? 274 ILE A CG1 1 
ATOM   1862 C  CG2 . ILE A 1 286 ? 94.214  118.560 86.052  1.00 96.39 ? 274 ILE A CG2 1 
ATOM   1863 C  CD1 . ILE A 1 286 ? 93.983  116.849 83.503  1.00 96.39 ? 274 ILE A CD1 1 
ATOM   1864 N  N   . LYS A 1 287 ? 90.552  118.756 87.295  1.00 95.98 ? 275 LYS A N   1 
ATOM   1865 C  CA  . LYS A 1 287 ? 89.894  119.894 87.925  1.00 95.98 ? 275 LYS A CA  1 
ATOM   1866 C  C   . LYS A 1 287 ? 89.572  119.608 89.380  1.00 95.98 ? 275 LYS A C   1 
ATOM   1867 O  O   . LYS A 1 287 ? 89.801  120.438 90.234  1.00 95.98 ? 275 LYS A O   1 
ATOM   1868 C  CB  . LYS A 1 287 ? 88.614  120.251 87.171  1.00 95.98 ? 275 LYS A CB  1 
ATOM   1869 C  CG  . LYS A 1 287 ? 87.955  121.551 87.600  1.00 95.98 ? 275 LYS A CG  1 
ATOM   1870 C  CD  . LYS A 1 287 ? 88.887  122.736 87.409  1.00 95.98 ? 275 LYS A CD  1 
ATOM   1871 C  CE  . LYS A 1 287 ? 88.124  124.048 87.472  1.00 95.98 ? 275 LYS A CE  1 
ATOM   1872 N  NZ  . LYS A 1 287 ? 87.277  124.154 88.691  1.00 95.98 ? 275 LYS A NZ  1 
ATOM   1873 N  N   . PHE A 1 288 ? 89.074  118.416 89.672  1.00 93.21 ? 276 PHE A N   1 
ATOM   1874 C  CA  . PHE A 1 288 ? 88.773  118.060 91.047  1.00 93.21 ? 276 PHE A CA  1 
ATOM   1875 C  C   . PHE A 1 288 ? 90.046  118.067 91.865  1.00 93.21 ? 276 PHE A C   1 
ATOM   1876 O  O   . PHE A 1 288 ? 90.079  118.595 92.974  1.00 93.21 ? 276 PHE A O   1 
ATOM   1877 C  CB  . PHE A 1 288 ? 88.131  116.674 91.074  1.00 93.21 ? 276 PHE A CB  1 
ATOM   1878 C  CG  . PHE A 1 288 ? 88.087  116.033 92.431  1.00 93.21 ? 276 PHE A CG  1 
ATOM   1879 C  CD1 . PHE A 1 288 ? 87.212  116.488 93.403  1.00 93.21 ? 276 PHE A CD1 1 
ATOM   1880 C  CD2 . PHE A 1 288 ? 88.891  114.942 92.719  1.00 93.21 ? 276 PHE A CD2 1 
ATOM   1881 C  CE1 . PHE A 1 288 ? 87.161  115.885 94.645  1.00 93.21 ? 276 PHE A CE1 1 
ATOM   1882 C  CE2 . PHE A 1 288 ? 88.843  114.335 93.958  1.00 93.21 ? 276 PHE A CE2 1 
ATOM   1883 C  CZ  . PHE A 1 288 ? 87.976  114.805 94.921  1.00 93.21 ? 276 PHE A CZ  1 
ATOM   1884 N  N   . TYR A 1 289 ? 91.096  117.483 91.310  1.00 94.75 ? 277 TYR A N   1 
ATOM   1885 C  CA  . TYR A 1 289 ? 92.382  117.439 91.980  1.00 94.75 ? 277 TYR A CA  1 
ATOM   1886 C  C   . TYR A 1 289 ? 92.858  118.839 92.279  1.00 94.75 ? 277 TYR A C   1 
ATOM   1887 O  O   . TYR A 1 289 ? 93.074  119.182 93.429  1.00 94.75 ? 277 TYR A O   1 
ATOM   1888 C  CB  . TYR A 1 289 ? 93.345  116.760 91.021  1.00 94.75 ? 277 TYR A CB  1 
ATOM   1889 C  CG  . TYR A 1 289 ? 94.739  116.477 91.499  1.00 94.75 ? 277 TYR A CG  1 
ATOM   1890 C  CD1 . TYR A 1 289 ? 95.005  116.154 92.819  1.00 94.75 ? 277 TYR A CD1 1 
ATOM   1891 C  CD2 . TYR A 1 289 ? 95.789  116.481 90.598  1.00 94.75 ? 277 TYR A CD2 1 
ATOM   1892 C  CE1 . TYR A 1 289 ? 96.293  115.874 93.231  1.00 94.75 ? 277 TYR A CE1 1 
ATOM   1893 C  CE2 . TYR A 1 289 ? 97.073  116.204 90.998  1.00 94.75 ? 277 TYR A CE2 1 
ATOM   1894 C  CZ  . TYR A 1 289 ? 97.318  115.901 92.312  1.00 94.75 ? 277 TYR A CZ  1 
ATOM   1895 O  OH  . TYR A 1 289 ? 98.602  115.622 92.688  1.00 94.75 ? 277 TYR A OH  1 
ATOM   1896 N  N   . LEU A 1 290 ? 93.046  119.649 91.246  1.00 96.26 ? 278 LEU A N   1 
ATOM   1897 C  CA  . LEU A 1 290 ? 93.577  121.000 91.437  1.00 96.26 ? 278 LEU A CA  1 
ATOM   1898 C  C   . LEU A 1 290 ? 92.730  121.993 92.230  1.00 96.26 ? 278 LEU A C   1 
ATOM   1899 O  O   . LEU A 1 290 ? 93.262  122.708 93.074  1.00 96.26 ? 278 LEU A O   1 
ATOM   1900 C  CB  . LEU A 1 290 ? 93.925  121.612 90.081  1.00 96.26 ? 278 LEU A CB  1 
ATOM   1901 C  CG  . LEU A 1 290 ? 94.990  120.867 89.284  1.00 96.26 ? 278 LEU A CG  1 
ATOM   1902 C  CD1 . LEU A 1 290 ? 95.366  121.657 88.042  1.00 96.26 ? 278 LEU A CD1 1 
ATOM   1903 C  CD2 . LEU A 1 290 ? 96.206  120.644 90.161  1.00 96.26 ? 278 LEU A CD2 1 
ATOM   1904 N  N   . TYR A 1 291 ? 91.425  122.043 91.982  1.00 95.15 ? 279 TYR A N   1 
ATOM   1905 C  CA  . TYR A 1 291 ? 90.586  123.043 92.645  1.00 95.15 ? 279 TYR A CA  1 
ATOM   1906 C  C   . TYR A 1 291 ? 90.503  122.799 94.135  1.00 95.15 ? 279 TYR A C   1 
ATOM   1907 O  O   . TYR A 1 291 ? 90.226  121.684 94.563  1.00 95.15 ? 279 TYR A O   1 
ATOM   1908 C  CB  . TYR A 1 291 ? 89.179  123.044 92.042  1.00 95.15 ? 279 TYR A CB  1 
ATOM   1909 C  CG  . TYR A 1 291 ? 88.249  124.081 92.628  1.00 95.15 ? 279 TYR A CG  1 
ATOM   1910 C  CD1 . TYR A 1 291 ? 88.325  125.409 92.233  1.00 95.15 ? 279 TYR A CD1 1 
ATOM   1911 C  CD2 . TYR A 1 291 ? 87.290  123.731 93.571  1.00 95.15 ? 279 TYR A CD2 1 
ATOM   1912 C  CE1 . TYR A 1 291 ? 87.478  126.361 92.766  1.00 95.15 ? 279 TYR A CE1 1 
ATOM   1913 C  CE2 . TYR A 1 291 ? 86.440  124.676 94.109  1.00 95.15 ? 279 TYR A CE2 1 
ATOM   1914 C  CZ  . TYR A 1 291 ? 86.538  125.990 93.702  1.00 95.15 ? 279 TYR A CZ  1 
ATOM   1915 O  OH  . TYR A 1 291 ? 85.691  126.935 94.234  1.00 95.15 ? 279 TYR A OH  1 
ATOM   1916 N  N   . PRO A 1 292 ? 90.684  123.857 94.934  1.00 93.64 ? 280 PRO A N   1 
ATOM   1917 C  CA  . PRO A 1 292 ? 90.667  123.700 96.388  1.00 93.64 ? 280 PRO A CA  1 
ATOM   1918 C  C   . PRO A 1 292 ? 89.344  124.106 97.015  1.00 93.64 ? 280 PRO A C   1 
ATOM   1919 O  O   . PRO A 1 292 ? 88.819  125.178 96.721  1.00 93.64 ? 280 PRO A O   1 
ATOM   1920 C  CB  . PRO A 1 292 ? 91.781  124.647 96.858  1.00 93.64 ? 280 PRO A CB  1 
ATOM   1921 C  CG  . PRO A 1 292 ? 92.230  125.418 95.650  1.00 93.64 ? 280 PRO A CG  1 
ATOM   1922 C  CD  . PRO A 1 292 ? 91.260  125.149 94.540  1.00 93.64 ? 280 PRO A CD  1 
ATOM   1923 N  N   . ASP A 1 293 ? 88.806  123.256 97.879  1.00 92.55 ? 281 ASP A N   1 
ATOM   1924 C  CA  . ASP A 1 293 ? 87.554  123.580 98.539  1.00 92.55 ? 281 ASP A CA  1 
ATOM   1925 C  C   . ASP A 1 293 ? 87.852  124.195 99.888  1.00 92.55 ? 281 ASP A C   1 
ATOM   1926 O  O   . ASP A 1 293 ? 88.392  123.536 100.773 1.00 92.55 ? 281 ASP A O   1 
ATOM   1927 C  CB  . ASP A 1 293 ? 86.708  122.321 98.719  1.00 92.55 ? 281 ASP A CB  1 
ATOM   1928 C  CG  . ASP A 1 293 ? 85.306  122.623 99.213  1.00 92.55 ? 281 ASP A CG  1 
ATOM   1929 O  OD1 . ASP A 1 293 ? 84.874  123.792 99.130  1.00 92.55 ? 281 ASP A OD1 1 
ATOM   1930 O  OD2 . ASP A 1 293 ? 84.628  121.684 99.677  1.00 92.55 ? 281 ASP A OD2 1 
ATOM   1931 N  N   . ILE A 1 294 ? 87.516  125.467 100.062 1.00 95.07 ? 282 ILE A N   1 
ATOM   1932 C  CA  . ILE A 1 294 ? 87.842  126.157 101.309 1.00 95.07 ? 282 ILE A CA  1 
ATOM   1933 C  C   . ILE A 1 294 ? 87.133  125.594 102.539 1.00 95.07 ? 282 ILE A C   1 
ATOM   1934 O  O   . ILE A 1 294 ? 87.667  125.645 103.650 1.00 95.07 ? 282 ILE A O   1 
ATOM   1935 C  CB  . ILE A 1 294 ? 87.572  127.665 101.193 1.00 95.07 ? 282 ILE A CB  1 
ATOM   1936 C  CG1 . ILE A 1 294 ? 86.173  127.914 100.627 1.00 95.07 ? 282 ILE A CG1 1 
ATOM   1937 C  CG2 . ILE A 1 294 ? 88.613  128.316 100.298 1.00 95.07 ? 282 ILE A CG2 1 
ATOM   1938 C  CD1 . ILE A 1 294 ? 85.820  129.379 100.494 1.00 95.07 ? 282 ILE A CD1 1 
ATOM   1939 N  N   . THR A 1 295 ? 85.936  125.053 102.351 1.00 95.78 ? 283 THR A N   1 
ATOM   1940 C  CA  . THR A 1 295 ? 85.177  124.533 103.481 1.00 95.78 ? 283 THR A CA  1 
ATOM   1941 C  C   . THR A 1 295 ? 85.906  123.374 104.143 1.00 95.78 ? 283 THR A C   1 
ATOM   1942 O  O   . THR A 1 295 ? 85.931  123.270 105.366 1.00 95.78 ? 283 THR A O   1 
ATOM   1943 C  CB  . THR A 1 295 ? 83.773  124.084 103.048 1.00 95.78 ? 283 THR A CB  1 
ATOM   1944 O  OG1 . THR A 1 295 ? 83.873  122.922 102.217 1.00 95.78 ? 283 THR A OG1 1 
ATOM   1945 C  CG2 . THR A 1 295 ? 83.080  125.194 102.277 1.00 95.78 ? 283 THR A CG2 1 
ATOM   1946 N  N   . ARG A 1 296 ? 86.497  122.499 103.341 1.00 92.88 ? 284 ARG A N   1 
ATOM   1947 C  CA  . ARG A 1 296 ? 87.248  121.369 103.880 1.00 92.88 ? 284 ARG A CA  1 
ATOM   1948 C  C   . ARG A 1 296 ? 88.481  121.801 104.657 1.00 92.88 ? 284 ARG A C   1 
ATOM   1949 O  O   . ARG A 1 296 ? 88.882  121.131 105.601 1.00 92.88 ? 284 ARG A O   1 
ATOM   1950 C  CB  . ARG A 1 296 ? 87.602  120.365 102.794 1.00 92.88 ? 284 ARG A CB  1 
ATOM   1951 C  CG  . ARG A 1 296 ? 86.404  119.642 102.209 1.00 92.88 ? 284 ARG A CG  1 
ATOM   1952 C  CD  . ARG A 1 296 ? 86.826  118.309 101.619 1.00 92.88 ? 284 ARG A CD  1 
ATOM   1953 N  NE  . ARG A 1 296 ? 87.573  117.512 102.588 1.00 92.88 ? 284 ARG A NE  1 
ATOM   1954 C  CZ  . ARG A 1 296 ? 87.025  116.627 103.415 1.00 92.88 ? 284 ARG A CZ  1 
ATOM   1955 N  NH1 . ARG A 1 296 ? 85.716  116.415 103.391 1.00 92.88 ? 284 ARG A NH1 1 
ATOM   1956 N  NH2 . ARG A 1 296 ? 87.785  115.951 104.264 1.00 92.88 ? 284 ARG A NH2 1 
ATOM   1957 N  N   . LEU A 1 297 ? 89.087  122.913 104.262 1.00 93.46 ? 285 LEU A N   1 
ATOM   1958 C  CA  . LEU A 1 297 ? 90.281  123.401 104.941 1.00 93.46 ? 285 LEU A CA  1 
ATOM   1959 C  C   . LEU A 1 297 ? 89.939  123.656 106.394 1.00 93.46 ? 285 LEU A C   1 
ATOM   1960 O  O   . LEU A 1 297 ? 90.759  123.422 107.276 1.00 93.46 ? 285 LEU A O   1 
ATOM   1961 C  CB  . LEU A 1 297 ? 90.783  124.691 104.305 1.00 93.46 ? 285 LEU A CB  1 
ATOM   1962 C  CG  . LEU A 1 297 ? 91.220  124.626 102.845 1.00 93.46 ? 285 LEU A CG  1 
ATOM   1963 C  CD1 . LEU A 1 297 ? 91.574  126.012 102.332 1.00 93.46 ? 285 LEU A CD1 1 
ATOM   1964 C  CD2 . LEU A 1 297 ? 92.408  123.695 102.717 1.00 93.46 ? 285 LEU A CD2 1 
ATOM   1965 N  N   . GLU A 1 298 ? 88.726  124.132 106.651 1.00 92.63 ? 286 GLU A N   1 
ATOM   1966 C  CA  . GLU A 1 298 ? 88.298  124.384 108.021 1.00 92.63 ? 286 GLU A CA  1 
ATOM   1967 C  C   . GLU A 1 298 ? 88.321  123.108 108.862 1.00 92.63 ? 286 GLU A C   1 
ATOM   1968 O  O   . GLU A 1 298 ? 88.744  123.133 110.018 1.00 92.63 ? 286 GLU A O   1 
ATOM   1969 C  CB  . GLU A 1 298 ? 86.895  125.003 108.014 1.00 92.63 ? 286 GLU A CB  1 
ATOM   1970 C  CG  . GLU A 1 298 ? 86.182  125.038 109.356 1.00 92.63 ? 286 GLU A CG  1 
ATOM   1971 C  CD  . GLU A 1 298 ? 85.152  123.934 109.496 1.00 92.63 ? 286 GLU A CD  1 
ATOM   1972 O  OE1 . GLU A 1 298 ? 84.644  123.731 110.618 1.00 92.63 ? 286 GLU A OE1 1 
ATOM   1973 O  OE2 . GLU A 1 298 ? 84.855  123.266 108.483 1.00 92.63 ? 286 GLU A OE2 1 
ATOM   1974 N  N   . ASP A 1 299 ? 87.893  121.990 108.286 1.00 88.90 ? 287 ASP A N   1 
ATOM   1975 C  CA  . ASP A 1 299 ? 87.881  120.724 109.014 1.00 88.90 ? 287 ASP A CA  1 
ATOM   1976 C  C   . ASP A 1 299 ? 89.298  120.319 109.398 1.00 88.90 ? 287 ASP A C   1 
ATOM   1977 O  O   . ASP A 1 299 ? 90.211  120.404 108.579 1.00 88.90 ? 287 ASP A O   1 
ATOM   1978 C  CB  . ASP A 1 299 ? 87.258  119.643 108.128 1.00 88.90 ? 287 ASP A CB  1 
ATOM   1979 C  CG  . ASP A 1 299 ? 86.877  118.396 108.895 1.00 88.90 ? 287 ASP A CG  1 
ATOM   1980 O  OD1 . ASP A 1 299 ? 86.152  118.511 109.905 1.00 88.90 ? 287 ASP A OD1 1 
ATOM   1981 O  OD2 . ASP A 1 299 ? 87.283  117.295 108.473 1.00 88.90 ? 287 ASP A OD2 1 
ATOM   1982 N  N   . PRO A 1 300 ? 89.492  119.866 110.645 1.00 85.37 ? 288 PRO A N   1 
ATOM   1983 C  CA  . PRO A 1 300 ? 90.823  119.456 111.115 1.00 85.37 ? 288 PRO A CA  1 
ATOM   1984 C  C   . PRO A 1 300 ? 91.390  118.266 110.374 1.00 85.37 ? 288 PRO A C   1 
ATOM   1985 O  O   . PRO A 1 300 ? 92.593  118.226 110.136 1.00 85.37 ? 288 PRO A O   1 
ATOM   1986 C  CB  . PRO A 1 300 ? 90.576  119.066 112.576 1.00 85.37 ? 288 PRO A CB  1 
ATOM   1987 C  CG  . PRO A 1 300 ? 89.103  118.849 112.685 1.00 85.37 ? 288 PRO A CG  1 
ATOM   1988 C  CD  . PRO A 1 300 ? 88.503  119.835 111.732 1.00 85.37 ? 288 PRO A CD  1 
ATOM   1989 N  N   . GLN A 1 301 ? 90.569  117.263 110.087 1.00 85.99 ? 289 GLN A N   1 
ATOM   1990 C  CA  . GLN A 1 301 ? 91.075  116.028 109.480 1.00 85.99 ? 289 GLN A CA  1 
ATOM   1991 C  C   . GLN A 1 301 ? 92.036  116.232 108.326 1.00 85.99 ? 289 GLN A C   1 
ATOM   1992 O  O   . GLN A 1 301 ? 93.063  115.559 108.249 1.00 85.99 ? 289 GLN A O   1 
ATOM   1993 C  CB  . GLN A 1 301 ? 89.911  115.138 109.041 1.00 85.99 ? 289 GLN A CB  1 
ATOM   1994 C  CG  . GLN A 1 301 ? 90.308  113.706 108.734 1.00 85.99 ? 289 GLN A CG  1 
ATOM   1995 C  CD  . GLN A 1 301 ? 90.861  112.985 109.947 1.00 85.99 ? 289 GLN A CD  1 
ATOM   1996 O  OE1 . GLN A 1 301 ? 91.867  112.285 109.859 1.00 85.99 ? 289 GLN A OE1 1 
ATOM   1997 N  NE2 . GLN A 1 301 ? 90.209  113.160 111.092 1.00 85.99 ? 289 GLN A NE2 1 
ATOM   1998 N  N   . VAL A 1 302 ? 91.735  117.175 107.445 1.00 90.80 ? 290 VAL A N   1 
ATOM   1999 C  CA  . VAL A 1 302 ? 92.568  117.358 106.267 1.00 90.80 ? 290 VAL A CA  1 
ATOM   2000 C  C   . VAL A 1 302 ? 93.992  117.733 106.639 1.00 90.80 ? 290 VAL A C   1 
ATOM   2001 O  O   . VAL A 1 302 ? 94.944  117.202 106.075 1.00 90.80 ? 290 VAL A O   1 
ATOM   2002 C  CB  . VAL A 1 302 ? 91.986  118.442 105.351 1.00 90.80 ? 290 VAL A CB  1 
ATOM   2003 C  CG1 . VAL A 1 302 ? 92.733  118.463 104.035 1.00 90.80 ? 290 VAL A CG1 1 
ATOM   2004 C  CG2 . VAL A 1 302 ? 90.510  118.181 105.109 1.00 90.80 ? 290 VAL A CG2 1 
ATOM   2005 N  N   . TRP A 1 303 ? 94.147  118.619 107.610 1.00 88.60 ? 291 TRP A N   1 
ATOM   2006 C  CA  . TRP A 1 303 ? 95.477  119.060 107.998 1.00 88.60 ? 291 TRP A CA  1 
ATOM   2007 C  C   . TRP A 1 303 ? 96.321  117.933 108.557 1.00 88.60 ? 291 TRP A C   1 
ATOM   2008 O  O   . TRP A 1 303 ? 97.499  117.825 108.238 1.00 88.60 ? 291 TRP A O   1 
ATOM   2009 C  CB  . TRP A 1 303 ? 95.388  120.196 109.012 1.00 88.60 ? 291 TRP A CB  1 
ATOM   2010 C  CG  . TRP A 1 303 ? 94.965  121.487 108.410 1.00 88.60 ? 291 TRP A CG  1 
ATOM   2011 C  CD1 . TRP A 1 303 ? 93.691  121.890 108.140 1.00 88.60 ? 291 TRP A CD1 1 
ATOM   2012 C  CD2 . TRP A 1 303 ? 95.821  122.554 107.997 1.00 88.60 ? 291 TRP A CD2 1 
ATOM   2013 N  NE1 . TRP A 1 303 ? 93.702  123.144 107.582 1.00 88.60 ? 291 TRP A NE1 1 
ATOM   2014 C  CE2 . TRP A 1 303 ? 94.999  123.574 107.484 1.00 88.60 ? 291 TRP A CE2 1 
ATOM   2015 C  CE3 . TRP A 1 303 ? 97.205  122.745 108.012 1.00 88.60 ? 291 TRP A CE3 1 
ATOM   2016 C  CZ2 . TRP A 1 303 ? 95.514  124.767 106.990 1.00 88.60 ? 291 TRP A CZ2 1 
ATOM   2017 C  CZ3 . TRP A 1 303 ? 97.714  123.929 107.521 1.00 88.60 ? 291 TRP A CZ3 1 
ATOM   2018 C  CH2 . TRP A 1 303 ? 96.871  124.925 107.018 1.00 88.60 ? 291 TRP A CH2 1 
ATOM   2019 N  N   . ILE A 1 304 ? 95.725  117.095 109.394 1.00 85.21 ? 292 ILE A N   1 
ATOM   2020 C  CA  . ILE A 1 304 ? 96.463  115.980 109.966 1.00 85.21 ? 292 ILE A CA  1 
ATOM   2021 C  C   . ILE A 1 304 ? 96.897  114.995 108.895 1.00 85.21 ? 292 ILE A C   1 
ATOM   2022 O  O   . ILE A 1 304 ? 98.046  114.575 108.872 1.00 85.21 ? 292 ILE A O   1 
ATOM   2023 C  CB  . ILE A 1 304 ? 95.657  115.262 111.062 1.00 85.21 ? 292 ILE A CB  1 
ATOM   2024 C  CG1 . ILE A 1 304 ? 95.455  116.192 112.252 1.00 85.21 ? 292 ILE A CG1 1 
ATOM   2025 C  CG2 . ILE A 1 304 ? 96.362  114.000 111.535 1.00 85.21 ? 292 ILE A CG2 1 
ATOM   2026 C  CD1 . ILE A 1 304 ? 94.457  115.659 113.251 1.00 85.21 ? 292 ILE A CD1 1 
ATOM   2027 N  N   . ASP A 1 305 ? 96.005  114.676 107.966 1.00 89.12 ? 293 ASP A N   1 
ATOM   2028 C  CA  . ASP A 1 305 ? 96.333  113.690 106.946 1.00 89.12 ? 293 ASP A CA  1 
ATOM   2029 C  C   . ASP A 1 305 ? 97.402  114.226 106.018 1.00 89.12 ? 293 ASP A C   1 
ATOM   2030 O  O   . ASP A 1 305 ? 98.262  113.479 105.572 1.00 89.12 ? 293 ASP A O   1 
ATOM   2031 C  CB  . ASP A 1 305 ? 95.095  113.301 106.147 1.00 89.12 ? 293 ASP A CB  1 
ATOM   2032 C  CG  . ASP A 1 305 ? 94.063  112.587 106.987 1.00 89.12 ? 293 ASP A CG  1 
ATOM   2033 O  OD1 . ASP A 1 305 ? 94.392  112.200 108.127 1.00 89.12 ? 293 ASP A OD1 1 
ATOM   2034 O  OD2 . ASP A 1 305 ? 92.925  112.410 106.506 1.00 89.12 ? 293 ASP A OD2 1 
ATOM   2035 N  N   . ALA A 1 306 ? 97.356  115.522 105.735 1.00 92.32 ? 294 ALA A N   1 
ATOM   2036 C  CA  . ALA A 1 306 ? 98.337  116.131 104.850 1.00 92.32 ? 294 ALA A CA  1 
ATOM   2037 C  C   . ALA A 1 306 ? 99.702  116.279 105.470 1.00 92.32 ? 294 ALA A C   1 
ATOM   2038 O  O   . ALA A 1 306 ? 100.714 115.981 104.842 1.00 92.32 ? 294 ALA A O   1 
ATOM   2039 C  CB  . ALA A 1 306 ? 97.839  117.474 104.375 1.00 92.32 ? 294 ALA A CB  1 
ATOM   2040 N  N   . GLY A 1 307 ? 99.736  116.743 106.709 1.00 89.00 ? 295 GLY A N   1 
ATOM   2041 C  CA  . GLY A 1 307 ? 101.002 116.934 107.376 1.00 89.00 ? 295 GLY A CA  1 
ATOM   2042 C  C   . GLY A 1 307 ? 101.705 115.630 107.596 1.00 89.00 ? 295 GLY A C   1 
ATOM   2043 O  O   . GLY A 1 307 ? 102.905 115.510 107.360 1.00 89.00 ? 295 GLY A O   1 
ATOM   2044 N  N   . THR A 1 308 ? 100.951 114.636 108.034 1.00 87.55 ? 296 THR A N   1 
ATOM   2045 C  CA  . THR A 1 308 ? 101.534 113.331 108.246 1.00 87.55 ? 296 THR A CA  1 
ATOM   2046 C  C   . THR A 1 308 ? 101.999 112.695 106.942 1.00 87.55 ? 296 THR A C   1 
ATOM   2047 O  O   . THR A 1 308 ? 103.008 112.009 106.928 1.00 87.55 ? 296 THR A O   1 
ATOM   2048 C  CB  . THR A 1 308 ? 100.642 112.413 109.083 1.00 87.55 ? 296 THR A CB  1 
ATOM   2049 O  OG1 . THR A 1 308 ? 99.387  112.261 108.414 1.00 87.55 ? 296 THR A OG1 1 
ATOM   2050 C  CG2 . THR A 1 308 ? 100.426 112.964 110.488 1.00 87.55 ? 296 THR A CG2 1 
ATOM   2051 N  N   . GLN A 1 309 ? 101.264 112.919 105.856 1.00 92.78 ? 297 GLN A N   1 
ATOM   2052 C  CA  . GLN A 1 309 ? 101.677 112.390 104.558 1.00 92.78 ? 297 GLN A CA  1 
ATOM   2053 C  C   . GLN A 1 309 ? 103.035 112.947 104.183 1.00 92.78 ? 297 GLN A C   1 
ATOM   2054 O  O   . GLN A 1 309 ? 103.870 112.230 103.662 1.00 92.78 ? 297 GLN A O   1 
ATOM   2055 C  CB  . GLN A 1 309 ? 100.636 112.671 103.467 1.00 92.78 ? 297 GLN A CB  1 
ATOM   2056 C  CG  . GLN A 1 309 ? 101.116 112.530 102.028 1.00 92.78 ? 297 GLN A CG  1 
ATOM   2057 C  CD  . GLN A 1 309 ? 101.525 111.118 101.651 1.00 92.78 ? 297 GLN A CD  1 
ATOM   2058 O  OE1 . GLN A 1 309 ? 101.327 110.174 102.410 1.00 92.78 ? 297 GLN A OE1 1 
ATOM   2059 N  NE2 . GLN A 1 309 ? 102.104 110.970 100.467 1.00 92.78 ? 297 GLN A NE2 1 
ATOM   2060 N  N   . ILE A 1 310 ? 103.279 114.216 104.475 1.00 93.58 ? 298 ILE A N   1 
ATOM   2061 C  CA  . ILE A 1 310 ? 104.590 114.784 104.208 1.00 93.58 ? 298 ILE A CA  1 
ATOM   2062 C  C   . ILE A 1 310 ? 105.651 114.065 105.036 1.00 93.58 ? 298 ILE A C   1 
ATOM   2063 O  O   . ILE A 1 310 ? 106.718 113.732 104.527 1.00 93.58 ? 298 ILE A O   1 
ATOM   2064 C  CB  . ILE A 1 310 ? 104.604 116.297 104.486 1.00 93.58 ? 298 ILE A CB  1 
ATOM   2065 C  CG1 . ILE A 1 310 ? 104.001 117.052 103.312 1.00 93.58 ? 298 ILE A CG1 1 
ATOM   2066 C  CG2 . ILE A 1 310 ? 106.016 116.803 104.679 1.00 93.58 ? 298 ILE A CG2 1 
ATOM   2067 C  CD1 . ILE A 1 310 ? 104.901 117.050 102.100 1.00 93.58 ? 298 ILE A CD1 1 
ATOM   2068 N  N   . PHE A 1 311 ? 105.347 113.778 106.297 1.00 91.54 ? 299 PHE A N   1 
ATOM   2069 C  CA  . PHE A 1 311 ? 106.306 113.099 107.160 1.00 91.54 ? 299 PHE A CA  1 
ATOM   2070 C  C   . PHE A 1 311 ? 106.435 111.627 106.798 1.00 91.54 ? 299 PHE A C   1 
ATOM   2071 O  O   . PHE A 1 311 ? 107.492 111.036 106.992 1.00 91.54 ? 299 PHE A O   1 
ATOM   2072 C  CB  . PHE A 1 311 ? 105.940 113.266 108.631 1.00 91.54 ? 299 PHE A CB  1 
ATOM   2073 C  CG  . PHE A 1 311 ? 105.960 114.689 109.105 1.00 91.54 ? 299 PHE A CG  1 
ATOM   2074 C  CD1 . PHE A 1 311 ? 107.030 115.514 108.816 1.00 91.54 ? 299 PHE A CD1 1 
ATOM   2075 C  CD2 . PHE A 1 311 ? 104.916 115.195 109.858 1.00 91.54 ? 299 PHE A CD2 1 
ATOM   2076 C  CE1 . PHE A 1 311 ? 107.053 116.823 109.253 1.00 91.54 ? 299 PHE A CE1 1 
ATOM   2077 C  CE2 . PHE A 1 311 ? 104.931 116.503 110.298 1.00 91.54 ? 299 PHE A CE2 1 
ATOM   2078 C  CZ  . PHE A 1 311 ? 106.002 117.319 109.997 1.00 91.54 ? 299 PHE A CZ  1 
ATOM   2079 N  N   . PHE A 1 312 ? 105.370 111.023 106.286 1.00 89.78 ? 300 PHE A N   1 
ATOM   2080 C  CA  . PHE A 1 312 ? 105.453 109.637 105.822 1.00 89.78 ? 300 PHE A CA  1 
ATOM   2081 C  C   . PHE A 1 312 ? 106.155 109.520 104.476 1.00 89.78 ? 300 PHE A C   1 
ATOM   2082 O  O   . PHE A 1 312 ? 107.001 108.649 104.291 1.00 89.78 ? 300 PHE A O   1 
ATOM   2083 C  CB  . PHE A 1 312 ? 104.035 109.060 105.732 1.00 89.78 ? 300 PHE A CB  1 
ATOM   2084 C  CG  . PHE A 1 312 ? 103.943 107.733 105.032 1.00 89.78 ? 300 PHE A CG  1 
ATOM   2085 C  CD1 . PHE A 1 312 ? 104.108 106.556 105.733 1.00 89.78 ? 300 PHE A CD1 1 
ATOM   2086 C  CD2 . PHE A 1 312 ? 103.653 107.662 103.678 1.00 89.78 ? 300 PHE A CD2 1 
ATOM   2087 C  CE1 . PHE A 1 312 ? 104.011 105.334 105.095 1.00 89.78 ? 300 PHE A CE1 1 
ATOM   2088 C  CE2 . PHE A 1 312 ? 103.563 106.444 103.036 1.00 89.78 ? 300 PHE A CE2 1 
ATOM   2089 C  CZ  . PHE A 1 312 ? 103.739 105.277 103.745 1.00 89.78 ? 300 PHE A CZ  1 
ATOM   2090 N  N   . SER A 1 313 ? 105.819 110.400 103.539 1.00 93.99 ? 301 SER A N   1 
ATOM   2091 C  CA  . SER A 1 313 ? 106.407 110.350 102.203 1.00 93.99 ? 301 SER A CA  1 
ATOM   2092 C  C   . SER A 1 313 ? 107.891 110.615 102.219 1.00 93.99 ? 301 SER A C   1 
ATOM   2093 O  O   . SER A 1 313 ? 108.639 109.996 101.481 1.00 93.99 ? 301 SER A O   1 
ATOM   2094 C  CB  . SER A 1 313 ? 105.720 111.338 101.270 1.00 93.99 ? 301 SER A CB  1 
ATOM   2095 O  OG  . SER A 1 313 ? 106.100 111.106 99.931  1.00 93.99 ? 301 SER A OG  1 
ATOM   2096 N  N   . TYR A 1 314 ? 108.324 111.553 103.049 1.00 93.31 ? 302 TYR A N   1 
ATOM   2097 C  CA  . TYR A 1 314 ? 109.738 111.892 103.122 1.00 93.31 ? 302 TYR A CA  1 
ATOM   2098 C  C   . TYR A 1 314 ? 110.450 111.009 104.121 1.00 93.31 ? 302 TYR A C   1 
ATOM   2099 O  O   . TYR A 1 314 ? 111.643 111.186 104.345 1.00 93.31 ? 302 TYR A O   1 
ATOM   2100 C  CB  . TYR A 1 314 ? 109.924 113.359 103.490 1.00 93.31 ? 302 TYR A CB  1 
ATOM   2101 C  CG  . TYR A 1 314 ? 109.898 114.304 102.320 1.00 93.31 ? 302 TYR A CG  1 
ATOM   2102 C  CD1 . TYR A 1 314 ? 108.700 114.784 101.815 1.00 93.31 ? 302 TYR A CD1 1 
ATOM   2103 C  CD2 . TYR A 1 314 ? 111.076 114.724 101.725 1.00 93.31 ? 302 TYR A CD2 1 
ATOM   2104 C  CE1 . TYR A 1 314 ? 108.676 115.651 100.744 1.00 93.31 ? 302 TYR A CE1 1 
ATOM   2105 C  CE2 . TYR A 1 314 ? 111.062 115.592 100.655 1.00 93.31 ? 302 TYR A CE2 1 
ATOM   2106 C  CZ  . TYR A 1 314 ? 109.860 116.052 100.169 1.00 93.31 ? 302 TYR A CZ  1 
ATOM   2107 O  OH  . TYR A 1 314 ? 109.846 116.918 99.103  1.00 93.31 ? 302 TYR A OH  1 
ATOM   2108 N  N   . ALA A 1 315 ? 109.715 110.110 104.767 1.00 92.95 ? 303 ALA A N   1 
ATOM   2109 C  CA  . ALA A 1 315 ? 110.293 109.193 105.749 1.00 92.95 ? 303 ALA A CA  1 
ATOM   2110 C  C   . ALA A 1 315 ? 110.944 109.945 106.883 1.00 92.95 ? 303 ALA A C   1 
ATOM   2111 O  O   . ALA A 1 315 ? 111.929 109.485 107.456 1.00 92.95 ? 303 ALA A O   1 
ATOM   2112 C  CB  . ALA A 1 315 ? 111.265 108.217 105.107 1.00 92.95 ? 303 ALA A CB  1 
ATOM   2113 N  N   . ILE A 1 316 ? 110.392 111.101 107.228 1.00 94.25 ? 304 ILE A N   1 
ATOM   2114 C  CA  . ILE A 1 316 ? 110.909 111.859 108.357 1.00 94.25 ? 304 ILE A CA  1 
ATOM   2115 C  C   . ILE A 1 316 ? 110.355 111.244 109.623 1.00 94.25 ? 304 ILE A C   1 
ATOM   2116 O  O   . ILE A 1 316 ? 109.242 110.718 109.594 1.00 94.25 ? 304 ILE A O   1 
ATOM   2117 C  CB  . ILE A 1 316 ? 110.467 113.326 108.299 1.00 94.25 ? 304 ILE A CB  1 
ATOM   2118 C  CG1 . ILE A 1 316 ? 110.559 113.857 106.878 1.00 94.25 ? 304 ILE A CG1 1 
ATOM   2119 C  CG2 . ILE A 1 316 ? 111.325 114.178 109.210 1.00 94.25 ? 304 ILE A CG2 1 
ATOM   2120 C  CD1 . ILE A 1 316 ? 110.035 115.264 106.734 1.00 94.25 ? 304 ILE A CD1 1 
ATOM   2121 N  N   . CYS A 1 317 ? 111.133 111.247 110.705 1.00 95.42 ? 305 CYS A N   1 
ATOM   2122 C  CA  . CYS A 1 317 ? 110.693 110.720 112.007 1.00 95.42 ? 305 CYS A CA  1 
ATOM   2123 C  C   . CYS A 1 317 ? 110.626 109.205 112.032 1.00 95.42 ? 305 CYS A C   1 
ATOM   2124 O  O   . CYS A 1 317 ? 110.110 108.620 112.980 1.00 95.42 ? 305 CYS A O   1 
ATOM   2125 C  CB  . CYS A 1 317 ? 109.378 111.344 112.482 1.00 95.42 ? 305 CYS A CB  1 
ATOM   2126 S  SG  . CYS A 1 317 ? 109.327 113.142 112.369 1.00 95.42 ? 305 CYS A SG  1 
ATOM   2127 N  N   . LEU A 1 318 ? 111.158 108.566 111.000 1.00 95.73 ? 306 LEU A N   1 
ATOM   2128 C  CA  . LEU A 1 318 ? 111.194 107.117 110.966 1.00 95.73 ? 306 LEU A CA  1 
ATOM   2129 C  C   . LEU A 1 318 ? 112.642 106.770 111.175 1.00 95.73 ? 306 LEU A C   1 
ATOM   2130 O  O   . LEU A 1 318 ? 113.035 105.619 111.051 1.00 95.73 ? 306 LEU A O   1 
ATOM   2131 C  CB  . LEU A 1 318 ? 110.719 106.587 109.619 1.00 95.73 ? 306 LEU A CB  1 
ATOM   2132 C  CG  . LEU A 1 318 ? 109.282 106.921 109.225 1.00 95.73 ? 306 LEU A CG  1 
ATOM   2133 C  CD1 . LEU A 1 318 ? 109.032 106.593 107.767 1.00 95.73 ? 306 LEU A CD1 1 
ATOM   2134 C  CD2 . LEU A 1 318 ? 108.313 106.155 110.100 1.00 95.73 ? 306 LEU A CD2 1 
ATOM   2135 N  N   . GLY A 1 319 ? 113.451 107.778 111.479 1.00 95.50 ? 307 GLY A N   1 
ATOM   2136 C  CA  . GLY A 1 319 ? 114.856 107.522 111.756 1.00 95.50 ? 307 GLY A CA  1 
ATOM   2137 C  C   . GLY A 1 319 ? 115.636 107.015 110.561 1.00 95.50 ? 307 GLY A C   1 
ATOM   2138 O  O   . GLY A 1 319 ? 116.864 106.958 110.601 1.00 95.50 ? 307 GLY A O   1 
ATOM   2139 N  N   . ALA A 1 320 ? 114.936 106.639 109.495 1.00 96.34 ? 308 ALA A N   1 
ATOM   2140 C  CA  . ALA A 1 320 ? 115.594 106.121 108.298 1.00 96.34 ? 308 ALA A CA  1 
ATOM   2141 C  C   . ALA A 1 320 ? 116.490 107.158 107.641 1.00 96.34 ? 308 ALA A C   1 
ATOM   2142 O  O   . ALA A 1 320 ? 117.591 106.841 107.202 1.00 96.34 ? 308 ALA A O   1 
ATOM   2143 C  CB  . ALA A 1 320 ? 114.560 105.618 107.306 1.00 96.34 ? 308 ALA A CB  1 
ATOM   2144 N  N   . MET A 1 321 ? 116.034 108.404 107.574 1.00 96.81 ? 309 MET A N   1 
ATOM   2145 C  CA  . MET A 1 321 ? 116.819 109.435 106.906 1.00 96.81 ? 309 MET A CA  1 
ATOM   2146 C  C   . MET A 1 321 ? 118.105 109.754 107.653 1.00 96.81 ? 309 MET A C   1 
ATOM   2147 O  O   . MET A 1 321 ? 119.130 110.032 107.035 1.00 96.81 ? 309 MET A O   1 
ATOM   2148 C  CB  . MET A 1 321 ? 115.986 110.694 106.672 1.00 96.81 ? 309 MET A CB  1 
ATOM   2149 C  CG  . MET A 1 321 ? 114.944 110.513 105.585 1.00 96.81 ? 309 MET A CG  1 
ATOM   2150 S  SD  . MET A 1 321 ? 115.707 109.835 104.099 1.00 96.81 ? 309 MET A SD  1 
ATOM   2151 C  CE  . MET A 1 321 ? 114.276 109.414 103.112 1.00 96.81 ? 309 MET A CE  1 
ATOM   2152 N  N   . THR A 1 322 ? 118.062 109.698 108.978 1.00 97.66 ? 310 THR A N   1 
ATOM   2153 C  CA  . THR A 1 322 ? 119.242 110.023 109.775 1.00 97.66 ? 310 THR A CA  1 
ATOM   2154 C  C   . THR A 1 322 ? 120.392 109.056 109.508 1.00 97.66 ? 310 THR A C   1 
ATOM   2155 O  O   . THR A 1 322 ? 121.542 109.474 109.391 1.00 97.66 ? 310 THR A O   1 
ATOM   2156 C  CB  . THR A 1 322 ? 118.914 110.023 111.276 1.00 97.66 ? 310 THR A CB  1 
ATOM   2157 O  OG1 . THR A 1 322 ? 117.672 110.702 111.495 1.00 97.66 ? 310 THR A OG1 1 
ATOM   2158 C  CG2 . THR A 1 322 ? 120.012 110.716 112.065 1.00 97.66 ? 310 THR A CG2 1 
ATOM   2159 N  N   . SER A 1 323 ? 120.087 107.768 109.395 1.00 96.84 ? 311 SER A N   1 
ATOM   2160 C  CA  . SER A 1 323 ? 121.120 106.773 109.127 1.00 96.84 ? 311 SER A CA  1 
ATOM   2161 C  C   . SER A 1 323 ? 121.771 107.000 107.775 1.00 96.84 ? 311 SER A C   1 
ATOM   2162 O  O   . SER A 1 323 ? 122.984 106.858 107.636 1.00 96.84 ? 311 SER A O   1 
ATOM   2163 C  CB  . SER A 1 323 ? 120.539 105.364 109.204 1.00 96.84 ? 311 SER A CB  1 
ATOM   2164 O  OG  . SER A 1 323 ? 119.547 105.162 108.215 1.00 96.84 ? 311 SER A OG  1 
ATOM   2165 N  N   . LEU A 1 324 ? 120.972 107.353 106.774 1.00 96.94 ? 312 LEU A N   1 
ATOM   2166 C  CA  . LEU A 1 324 ? 121.508 107.608 105.442 1.00 96.94 ? 312 LEU A CA  1 
ATOM   2167 C  C   . LEU A 1 324 ? 122.457 108.781 105.508 1.00 96.94 ? 312 LEU A C   1 
ATOM   2168 O  O   . LEU A 1 324 ? 123.507 108.770 104.869 1.00 96.94 ? 312 LEU A O   1 
ATOM   2169 C  CB  . LEU A 1 324 ? 120.381 107.886 104.453 1.00 96.94 ? 312 LEU A CB  1 
ATOM   2170 C  CG  . LEU A 1 324 ? 119.458 106.697 104.191 1.00 96.94 ? 312 LEU A CG  1 
ATOM   2171 C  CD1 . LEU A 1 324 ? 118.296 107.095 103.296 1.00 96.94 ? 312 LEU A CD1 1 
ATOM   2172 C  CD2 . LEU A 1 324 ? 120.241 105.546 103.583 1.00 96.94 ? 312 LEU A CD2 1 
ATOM   2173 N  N   . GLY A 1 325 ? 122.100 109.794 106.286 1.00 97.35 ? 313 GLY A N   1 
ATOM   2174 C  CA  . GLY A 1 325 ? 122.976 110.936 106.462 1.00 97.35 ? 313 GLY A CA  1 
ATOM   2175 C  C   . GLY A 1 325 ? 124.276 110.534 107.119 1.00 97.35 ? 313 GLY A C   1 
ATOM   2176 O  O   . GLY A 1 325 ? 125.332 111.052 106.772 1.00 97.35 ? 313 GLY A O   1 
ATOM   2177 N  N   . SER A 1 326 ? 124.213 109.609 108.069 1.00 96.46 ? 314 SER A N   1 
ATOM   2178 C  CA  . SER A 1 326 ? 125.409 109.202 108.799 1.00 96.46 ? 314 SER A CA  1 
ATOM   2179 C  C   . SER A 1 326 ? 126.468 108.608 107.897 1.00 96.46 ? 314 SER A C   1 
ATOM   2180 O  O   . SER A 1 326 ? 127.658 108.851 108.088 1.00 96.46 ? 314 SER A O   1 
ATOM   2181 C  CB  . SER A 1 326 ? 125.051 108.198 109.885 1.00 96.46 ? 314 SER A CB  1 
ATOM   2182 O  OG  . SER A 1 326 ? 126.221 107.613 110.416 1.00 96.46 ? 314 SER A OG  1 
ATOM   2183 N  N   . TYR A 1 327 ? 126.045 107.839 106.902 1.00 96.06 ? 315 TYR A N   1 
ATOM   2184 C  CA  . TYR A 1 327 ? 126.991 107.236 105.974 1.00 96.06 ? 315 TYR A CA  1 
ATOM   2185 C  C   . TYR A 1 327 ? 127.601 108.291 105.080 1.00 96.06 ? 315 TYR A C   1 
ATOM   2186 O  O   . TYR A 1 327 ? 128.737 108.160 104.641 1.00 96.06 ? 315 TYR A O   1 
ATOM   2187 C  CB  . TYR A 1 327 ? 126.308 106.178 105.118 1.00 96.06 ? 315 TYR A CB  1 
ATOM   2188 C  CG  . TYR A 1 327 ? 125.740 105.028 105.904 1.00 96.06 ? 315 TYR A CG  1 
ATOM   2189 C  CD1 . TYR A 1 327 ? 126.527 104.324 106.803 1.00 96.06 ? 315 TYR A CD1 1 
ATOM   2190 C  CD2 . TYR A 1 327 ? 124.423 104.634 105.735 1.00 96.06 ? 315 TYR A CD2 1 
ATOM   2191 C  CE1 . TYR A 1 327 ? 126.013 103.265 107.521 1.00 96.06 ? 315 TYR A CE1 1 
ATOM   2192 C  CE2 . TYR A 1 327 ? 123.898 103.577 106.450 1.00 96.06 ? 315 TYR A CE2 1 
ATOM   2193 C  CZ  . TYR A 1 327 ? 124.698 102.897 107.342 1.00 96.06 ? 315 TYR A CZ  1 
ATOM   2194 O  OH  . TYR A 1 327 ? 124.181 101.843 108.056 1.00 96.06 ? 315 TYR A OH  1 
ATOM   2195 N  N   . ASN A 1 328 ? 126.845 109.343 104.805 1.00 95.67 ? 316 ASN A N   1 
ATOM   2196 C  CA  . ASN A 1 328 ? 127.337 110.410 103.950 1.00 95.67 ? 316 ASN A CA  1 
ATOM   2197 C  C   . ASN A 1 328 ? 128.507 111.090 104.628 1.00 95.67 ? 316 ASN A C   1 
ATOM   2198 O  O   . ASN A 1 328 ? 128.513 111.253 105.846 1.00 95.67 ? 316 ASN A O   1 
ATOM   2199 C  CB  . ASN A 1 328 ? 126.225 111.415 103.694 1.00 95.67 ? 316 ASN A CB  1 
ATOM   2200 C  CG  . ASN A 1 328 ? 126.437 112.216 102.433 1.00 95.67 ? 316 ASN A CG  1 
ATOM   2201 O  OD1 . ASN A 1 328 ? 127.421 112.035 101.716 1.00 95.67 ? 316 ASN A OD1 1 
ATOM   2202 N  ND2 . ASN A 1 328 ? 125.502 113.107 102.151 1.00 95.67 ? 316 ASN A ND2 1 
ATOM   2203 N  N   . LYS A 1 329 ? 129.503 111.494 103.849 1.00 93.38 ? 317 LYS A N   1 
ATOM   2204 C  CA  . LYS A 1 329 ? 130.693 112.115 104.423 1.00 93.38 ? 317 LYS A CA  1 
ATOM   2205 C  C   . LYS A 1 329 ? 130.425 113.459 105.086 1.00 93.38 ? 317 LYS A C   1 
ATOM   2206 O  O   . LYS A 1 329 ? 129.396 114.090 104.836 1.00 93.38 ? 317 LYS A O   1 
ATOM   2207 C  CB  . LYS A 1 329 ? 131.778 112.274 103.359 1.00 93.38 ? 317 LYS A CB  1 
ATOM   2208 C  CG  . LYS A 1 329 ? 131.348 113.098 102.158 1.00 93.38 ? 317 LYS A CG  1 
ATOM   2209 C  CD  . LYS A 1 329 ? 132.510 113.332 101.209 1.00 93.38 ? 317 LYS A CD  1 
ATOM   2210 C  CE  . LYS A 1 329 ? 132.064 114.104 99.980  1.00 93.38 ? 317 LYS A CE  1 
ATOM   2211 N  NZ  . LYS A 1 329 ? 133.194 114.379 99.052  1.00 93.38 ? 317 LYS A NZ  1 
ATOM   2212 N  N   . TYR A 1 330 ? 131.362 113.904 105.919 1.00 91.50 ? 318 TYR A N   1 
ATOM   2213 C  CA  . TYR A 1 330 ? 131.210 115.174 106.626 1.00 91.50 ? 318 TYR A CA  1 
ATOM   2214 C  C   . TYR A 1 330 ? 131.122 116.340 105.659 1.00 91.50 ? 318 TYR A C   1 
ATOM   2215 O  O   . TYR A 1 330 ? 130.148 117.089 105.675 1.00 91.50 ? 318 TYR A O   1 
ATOM   2216 C  CB  . TYR A 1 330 ? 132.401 115.371 107.561 1.00 91.50 ? 318 TYR A CB  1 
ATOM   2217 C  CG  . TYR A 1 330 ? 132.126 116.209 108.785 1.00 91.50 ? 318 TYR A CG  1 
ATOM   2218 C  CD1 . TYR A 1 330 ? 131.331 115.727 109.814 1.00 91.50 ? 318 TYR A CD1 1 
ATOM   2219 C  CD2 . TYR A 1 330 ? 132.689 117.468 108.927 1.00 91.50 ? 318 TYR A CD2 1 
ATOM   2220 C  CE1 . TYR A 1 330 ? 131.088 116.485 110.943 1.00 91.50 ? 318 TYR A CE1 1 
ATOM   2221 C  CE2 . TYR A 1 330 ? 132.453 118.233 110.053 1.00 91.50 ? 318 TYR A CE2 1 
ATOM   2222 C  CZ  . TYR A 1 330 ? 131.651 117.737 111.057 1.00 91.50 ? 318 TYR A CZ  1 
ATOM   2223 O  OH  . TYR A 1 330 ? 131.411 118.496 112.178 1.00 91.50 ? 318 TYR A OH  1 
ATOM   2224 N  N   . LYS A 1 331 ? 132.136 116.498 104.815 1.00 93.68 ? 319 LYS A N   1 
ATOM   2225 C  CA  . LYS A 1 331 ? 132.158 117.619 103.880 1.00 93.68 ? 319 LYS A CA  1 
ATOM   2226 C  C   . LYS A 1 331 ? 131.406 117.311 102.600 1.00 93.68 ? 319 LYS A C   1 
ATOM   2227 O  O   . LYS A 1 331 ? 132.018 117.014 101.579 1.00 93.68 ? 319 LYS A O   1 
ATOM   2228 C  CB  . LYS A 1 331 ? 133.595 118.010 103.546 1.00 93.68 ? 319 LYS A CB  1 
ATOM   2229 C  CG  . LYS A 1 331 ? 134.456 118.308 104.759 1.00 93.68 ? 319 LYS A CG  1 
ATOM   2230 C  CD  . LYS A 1 331 ? 133.863 119.428 105.594 1.00 93.68 ? 319 LYS A CD  1 
ATOM   2231 C  CE  . LYS A 1 331 ? 134.742 119.729 106.794 1.00 93.68 ? 319 LYS A CE  1 
ATOM   2232 N  NZ  . LYS A 1 331 ? 134.081 120.687 107.718 1.00 93.68 ? 319 LYS A NZ  1 
ATOM   2233 N  N   . TYR A 1 332 ? 130.083 117.398 102.643 1.00 95.02 ? 320 TYR A N   1 
ATOM   2234 C  CA  . TYR A 1 332 ? 129.270 117.141 101.463 1.00 95.02 ? 320 TYR A CA  1 
ATOM   2235 C  C   . TYR A 1 332 ? 128.170 118.186 101.450 1.00 95.02 ? 320 TYR A C   1 
ATOM   2236 O  O   . TYR A 1 332 ? 127.614 118.500 102.500 1.00 95.02 ? 320 TYR A O   1 
ATOM   2237 C  CB  . TYR A 1 332 ? 128.667 115.741 101.543 1.00 95.02 ? 320 TYR A CB  1 
ATOM   2238 C  CG  . TYR A 1 332 ? 127.915 115.299 100.308 1.00 95.02 ? 320 TYR A CG  1 
ATOM   2239 C  CD1 . TYR A 1 332 ? 128.585 114.768 99.217  1.00 95.02 ? 320 TYR A CD1 1 
ATOM   2240 C  CD2 . TYR A 1 332 ? 126.535 115.394 100.241 1.00 95.02 ? 320 TYR A CD2 1 
ATOM   2241 C  CE1 . TYR A 1 332 ? 127.901 114.356 98.091  1.00 95.02 ? 320 TYR A CE1 1 
ATOM   2242 C  CE2 . TYR A 1 332 ? 125.842 114.982 99.123  1.00 95.02 ? 320 TYR A CE2 1 
ATOM   2243 C  CZ  . TYR A 1 332 ? 126.529 114.465 98.049  1.00 95.02 ? 320 TYR A CZ  1 
ATOM   2244 O  OH  . TYR A 1 332 ? 125.840 114.056 96.933  1.00 95.02 ? 320 TYR A OH  1 
ATOM   2245 N  N   . ASN A 1 333 ? 127.860 118.738 100.281 1.00 96.97 ? 321 ASN A N   1 
ATOM   2246 C  CA  . ASN A 1 333 ? 126.858 119.782 100.221 1.00 96.97 ? 321 ASN A CA  1 
ATOM   2247 C  C   . ASN A 1 333 ? 125.524 119.083 100.179 1.00 96.97 ? 321 ASN A C   1 
ATOM   2248 O  O   . ASN A 1 333 ? 124.843 119.085 99.158  1.00 96.97 ? 321 ASN A O   1 
ATOM   2249 C  CB  . ASN A 1 333 ? 127.050 120.667 98.994  1.00 96.97 ? 321 ASN A CB  1 
ATOM   2250 C  CG  . ASN A 1 333 ? 126.359 122.011 99.128  1.00 96.97 ? 321 ASN A CG  1 
ATOM   2251 O  OD1 . ASN A 1 333 ? 125.631 122.259 100.090 1.00 96.97 ? 321 ASN A OD1 1 
ATOM   2252 N  ND2 . ASN A 1 333 ? 126.585 122.889 98.159  1.00 96.97 ? 321 ASN A ND2 1 
ATOM   2253 N  N   . SER A 1 334 ? 125.182 118.417 101.272 1.00 96.37 ? 322 SER A N   1 
ATOM   2254 C  CA  . SER A 1 334 ? 123.924 117.704 101.325 1.00 96.37 ? 322 SER A CA  1 
ATOM   2255 C  C   . SER A 1 334 ? 122.805 118.695 101.170 1.00 96.37 ? 322 SER A C   1 
ATOM   2256 O  O   . SER A 1 334 ? 121.725 118.344 100.744 1.00 96.37 ? 322 SER A O   1 
ATOM   2257 C  CB  . SER A 1 334 ? 123.781 116.967 102.647 1.00 96.37 ? 322 SER A CB  1 
ATOM   2258 O  OG  . SER A 1 334 ? 124.090 117.816 103.735 1.00 96.37 ? 322 SER A OG  1 
ATOM   2259 N  N   . TYR A 1 335 ? 123.061 119.948 101.511 1.00 97.28 ? 323 TYR A N   1 
ATOM   2260 C  CA  . TYR A 1 335 ? 121.996 120.923 101.457 1.00 97.28 ? 323 TYR A CA  1 
ATOM   2261 C  C   . TYR A 1 335 ? 121.522 121.049 100.032 1.00 97.28 ? 323 TYR A C   1 
ATOM   2262 O  O   . TYR A 1 335 ? 120.323 121.061 99.775  1.00 97.28 ? 323 TYR A O   1 
ATOM   2263 C  CB  . TYR A 1 335 ? 122.486 122.268 101.989 1.00 97.28 ? 323 TYR A CB  1 
ATOM   2264 C  CG  . TYR A 1 335 ? 121.410 123.311 102.149 1.00 97.28 ? 323 TYR A CG  1 
ATOM   2265 C  CD1 . TYR A 1 335 ? 120.148 122.970 102.608 1.00 97.28 ? 323 TYR A CD1 1 
ATOM   2266 C  CD2 . TYR A 1 335 ? 121.664 124.642 101.863 1.00 97.28 ? 323 TYR A CD2 1 
ATOM   2267 C  CE1 . TYR A 1 335 ? 119.164 123.924 102.756 1.00 97.28 ? 323 TYR A CE1 1 
ATOM   2268 C  CE2 . TYR A 1 335 ? 120.686 125.605 102.014 1.00 97.28 ? 323 TYR A CE2 1 
ATOM   2269 C  CZ  . TYR A 1 335 ? 119.437 125.239 102.462 1.00 97.28 ? 323 TYR A CZ  1 
ATOM   2270 O  OH  . TYR A 1 335 ? 118.456 126.190 102.616 1.00 97.28 ? 323 TYR A OH  1 
ATOM   2271 N  N   . ARG A 1 336 ? 122.452 121.121 99.091  1.00 96.95 ? 324 ARG A N   1 
ATOM   2272 C  CA  . ARG A 1 336 ? 122.051 121.164 97.700  1.00 96.95 ? 324 ARG A CA  1 
ATOM   2273 C  C   . ARG A 1 336 ? 121.370 119.874 97.273  1.00 96.95 ? 324 ARG A C   1 
ATOM   2274 O  O   . ARG A 1 336 ? 120.279 119.901 96.701  1.00 96.95 ? 324 ARG A O   1 
ATOM   2275 C  CB  . ARG A 1 336 ? 123.284 121.410 96.833  1.00 96.95 ? 324 ARG A CB  1 
ATOM   2276 C  CG  . ARG A 1 336 ? 123.118 121.083 95.361  1.00 96.95 ? 324 ARG A CG  1 
ATOM   2277 C  CD  . ARG A 1 336 ? 124.477 120.823 94.738  1.00 96.95 ? 324 ARG A CD  1 
ATOM   2278 N  NE  . ARG A 1 336 ? 125.221 119.823 95.499  1.00 96.95 ? 324 ARG A NE  1 
ATOM   2279 C  CZ  . ARG A 1 336 ? 126.473 119.463 95.238  1.00 96.95 ? 324 ARG A CZ  1 
ATOM   2280 N  NH1 . ARG A 1 336 ? 127.130 120.024 94.233  1.00 96.95 ? 324 ARG A NH1 1 
ATOM   2281 N  NH2 . ARG A 1 336 ? 127.071 118.544 95.985  1.00 96.95 ? 324 ARG A NH2 1 
ATOM   2282 N  N   . ASP A 1 337 ? 121.970 118.737 97.610  1.00 97.38 ? 325 ASP A N   1 
ATOM   2283 C  CA  . ASP A 1 337 ? 121.416 117.457 97.171  1.00 97.38 ? 325 ASP A CA  1 
ATOM   2284 C  C   . ASP A 1 337 ? 120.066 117.115 97.772  1.00 97.38 ? 325 ASP A C   1 
ATOM   2285 O  O   . ASP A 1 337 ? 119.175 116.662 97.067  1.00 97.38 ? 325 ASP A O   1 
ATOM   2286 C  CB  . ASP A 1 337 ? 122.418 116.331 97.406  1.00 97.38 ? 325 ASP A CB  1 
ATOM   2287 C  CG  . ASP A 1 337 ? 123.638 116.458 96.523  1.00 97.38 ? 325 ASP A CG  1 
ATOM   2288 O  OD1 . ASP A 1 337 ? 124.566 117.204 96.892  1.00 97.38 ? 325 ASP A OD1 1 
ATOM   2289 O  OD2 . ASP A 1 337 ? 123.669 115.819 95.452  1.00 97.38 ? 325 ASP A OD2 1 
ATOM   2290 N  N   . CYS A 1 338 ? 119.924 117.289 99.081  1.00 97.73 ? 326 CYS A N   1 
ATOM   2291 C  CA  . CYS A 1 338 ? 118.678 116.929 99.751  1.00 97.73 ? 326 CYS A CA  1 
ATOM   2292 C  C   . CYS A 1 338 ? 117.527 117.789 99.282  1.00 97.73 ? 326 CYS A C   1 
ATOM   2293 O  O   . CYS A 1 338 ? 116.422 117.296 99.090  1.00 97.73 ? 326 CYS A O   1 
ATOM   2294 C  CB  . CYS A 1 338 ? 118.829 117.017 101.267 1.00 97.73 ? 326 CYS A CB  1 
ATOM   2295 S  SG  . CYS A 1 338 ? 119.951 115.777 101.942 1.00 97.73 ? 326 CYS A SG  1 
ATOM   2296 N  N   . MET A 1 339 ? 117.772 119.078 99.104  1.00 97.29 ? 327 MET A N   1 
ATOM   2297 C  CA  . MET A 1 339 ? 116.725 119.939 98.589  1.00 97.29 ? 327 MET A CA  1 
ATOM   2298 C  C   . MET A 1 339 ? 116.324 119.540 97.175  1.00 97.29 ? 327 MET A C   1 
ATOM   2299 O  O   . MET A 1 339 ? 115.138 119.508 96.856  1.00 97.29 ? 327 MET A O   1 
ATOM   2300 C  CB  . MET A 1 339 ? 117.130 121.409 98.677  1.00 97.29 ? 327 MET A CB  1 
ATOM   2301 C  CG  . MET A 1 339 ? 117.195 121.911 100.108 1.00 97.29 ? 327 MET A CG  1 
ATOM   2302 S  SD  . MET A 1 339 ? 115.796 121.294 101.060 1.00 97.29 ? 327 MET A SD  1 
ATOM   2303 C  CE  . MET A 1 339 ? 116.277 121.728 102.728 1.00 97.29 ? 327 MET A CE  1 
ATOM   2304 N  N   . LEU A 1 340 ? 117.297 119.217 96.330  1.00 97.42 ? 328 LEU A N   1 
ATOM   2305 C  CA  . LEU A 1 340 ? 116.976 118.753 94.983  1.00 97.42 ? 328 LEU A CA  1 
ATOM   2306 C  C   . LEU A 1 340 ? 116.218 117.439 95.040  1.00 97.42 ? 328 LEU A C   1 
ATOM   2307 O  O   . LEU A 1 340 ? 115.271 117.228 94.288  1.00 97.42 ? 328 LEU A O   1 
ATOM   2308 C  CB  . LEU A 1 340 ? 118.243 118.588 94.145  1.00 97.42 ? 328 LEU A CB  1 
ATOM   2309 C  CG  . LEU A 1 340 ? 118.944 119.865 93.691  1.00 97.42 ? 328 LEU A CG  1 
ATOM   2310 C  CD1 . LEU A 1 340 ? 120.262 119.529 93.013  1.00 97.42 ? 328 LEU A CD1 1 
ATOM   2311 C  CD2 . LEU A 1 340 ? 118.043 120.668 92.767  1.00 97.42 ? 328 LEU A CD2 1 
ATOM   2312 N  N   . LEU A 1 341 ? 116.637 116.549 95.932  1.00 97.61 ? 329 LEU A N   1 
ATOM   2313 C  CA  . LEU A 1 341 ? 115.967 115.266 96.080  1.00 97.61 ? 329 LEU A CA  1 
ATOM   2314 C  C   . LEU A 1 341 ? 114.540 115.472 96.541  1.00 97.61 ? 329 LEU A C   1 
ATOM   2315 O  O   . LEU A 1 341 ? 113.630 114.803 96.070  1.00 97.61 ? 329 LEU A O   1 
ATOM   2316 C  CB  . LEU A 1 341 ? 116.725 114.393 97.075  1.00 97.61 ? 329 LEU A CB  1 
ATOM   2317 C  CG  . LEU A 1 341 ? 117.894 113.588 96.514  1.00 97.61 ? 329 LEU A CG  1 
ATOM   2318 C  CD1 . LEU A 1 341 ? 118.763 113.044 97.635  1.00 97.61 ? 329 LEU A CD1 1 
ATOM   2319 C  CD2 . LEU A 1 341 ? 117.371 112.468 95.631  1.00 97.61 ? 329 LEU A CD2 1 
ATOM   2320 N  N   . GLY A 1 342 ? 114.339 116.403 97.460  1.00 96.81 ? 330 GLY A N   1 
ATOM   2321 C  CA  . GLY A 1 342 ? 113.003 116.688 97.935  1.00 96.81 ? 330 GLY A CA  1 
ATOM   2322 C  C   . GLY A 1 342 ? 112.083 117.083 96.803  1.00 96.81 ? 330 GLY A C   1 
ATOM   2323 O  O   . GLY A 1 342 ? 110.940 116.645 96.747  1.00 96.81 ? 330 GLY A O   1 
ATOM   2324 N  N   . CYS A 1 343 ? 112.579 117.908 95.890  1.00 96.30 ? 331 CYS A N   1 
ATOM   2325 C  CA  . CYS A 1 343 ? 111.759 118.351 94.779  1.00 96.30 ? 331 CYS A CA  1 
ATOM   2326 C  C   . CYS A 1 343 ? 111.256 117.140 94.019  1.00 96.30 ? 331 CYS A C   1 
ATOM   2327 O  O   . CYS A 1 343 ? 110.104 117.100 93.607  1.00 96.30 ? 331 CYS A O   1 
ATOM   2328 C  CB  . CYS A 1 343 ? 112.555 119.258 93.845  1.00 96.30 ? 331 CYS A CB  1 
ATOM   2329 S  SG  . CYS A 1 343 ? 112.978 120.867 94.552  1.00 96.30 ? 331 CYS A SG  1 
ATOM   2330 N  N   . LEU A 1 344 ? 112.107 116.138 93.851  1.00 96.97 ? 332 LEU A N   1 
ATOM   2331 C  CA  . LEU A 1 344 ? 111.678 114.928 93.175  1.00 96.97 ? 332 LEU A CA  1 
ATOM   2332 C  C   . LEU A 1 344 ? 110.550 114.234 93.921  1.00 96.97 ? 332 LEU A C   1 
ATOM   2333 O  O   . LEU A 1 344 ? 109.587 113.804 93.303  1.00 96.97 ? 332 LEU A O   1 
ATOM   2334 C  CB  . LEU A 1 344 ? 112.854 113.962 93.022  1.00 96.97 ? 332 LEU A CB  1 
ATOM   2335 C  CG  . LEU A 1 344 ? 112.596 112.588 92.403  1.00 96.97 ? 332 LEU A CG  1 
ATOM   2336 C  CD1 . LEU A 1 344 ? 112.364 112.722 90.906  1.00 96.97 ? 332 LEU A CD1 1 
ATOM   2337 C  CD2 . LEU A 1 344 ? 113.768 111.660 92.679  1.00 96.97 ? 332 LEU A CD2 1 
ATOM   2338 N  N   . ASN A 1 345 ? 110.641 114.130 95.243  1.00 96.77 ? 333 ASN A N   1 
ATOM   2339 C  CA  . ASN A 1 345 ? 109.617 113.388 95.970  1.00 96.77 ? 333 ASN A CA  1 
ATOM   2340 C  C   . ASN A 1 345 ? 108.254 114.016 95.849  1.00 96.77 ? 333 ASN A C   1 
ATOM   2341 O  O   . ASN A 1 345 ? 107.275 113.337 95.557  1.00 96.77 ? 333 ASN A O   1 
ATOM   2342 C  CB  . ASN A 1 345 ? 109.951 113.382 97.449  1.00 96.77 ? 333 ASN A CB  1 
ATOM   2343 C  CG  . ASN A 1 345 ? 109.187 112.326 98.211  1.00 96.77 ? 333 ASN A CG  1 
ATOM   2344 O  OD1 . ASN A 1 345 ? 108.661 111.394 97.624  1.00 96.77 ? 333 ASN A OD1 1 
ATOM   2345 N  ND2 . ASN A 1 345 ? 109.153 112.449 99.526  1.00 96.77 ? 333 ASN A ND2 1 
ATOM   2346 N  N   . SER A 1 346 ? 108.186 115.320 96.067  1.00 96.59 ? 334 SER A N   1 
ATOM   2347 C  CA  . SER A 1 346 ? 106.922 116.019 95.938  1.00 96.59 ? 334 SER A CA  1 
ATOM   2348 C  C   . SER A 1 346 ? 106.482 116.053 94.499  1.00 96.59 ? 334 SER A C   1 
ATOM   2349 O  O   . SER A 1 346 ? 105.302 115.908 94.202  1.00 96.59 ? 334 SER A O   1 
ATOM   2350 C  CB  . SER A 1 346 ? 107.025 117.413 96.522  1.00 96.59 ? 334 SER A CB  1 
ATOM   2351 O  OG  . SER A 1 346 ? 107.303 117.322 97.903  1.00 96.59 ? 334 SER A OG  1 
ATOM   2352 N  N   . GLY A 1 347 ? 107.435 116.258 93.602  1.00 96.51 ? 335 GLY A N   1 
ATOM   2353 C  CA  . GLY A 1 347 ? 107.122 116.292 92.192  1.00 96.51 ? 335 GLY A CA  1 
ATOM   2354 C  C   . GLY A 1 347 ? 106.488 114.990 91.766  1.00 96.51 ? 335 GLY A C   1 
ATOM   2355 O  O   . GLY A 1 347 ? 105.475 114.998 91.078  1.00 96.51 ? 335 GLY A O   1 
ATOM   2356 N  N   . THR A 1 348 ? 107.073 113.865 92.170  1.00 96.72 ? 336 THR A N   1 
ATOM   2357 C  CA  . THR A 1 348 ? 106.539 112.582 91.711  1.00 96.72 ? 336 THR A CA  1 
ATOM   2358 C  C   . THR A 1 348 ? 105.181 112.334 92.322  1.00 96.72 ? 336 THR A C   1 
ATOM   2359 O  O   . THR A 1 348 ? 104.314 111.753 91.684  1.00 96.72 ? 336 THR A O   1 
ATOM   2360 C  CB  . THR A 1 348 ? 107.460 111.394 92.028  1.00 96.72 ? 336 THR A CB  1 
ATOM   2361 O  OG1 . THR A 1 348 ? 107.881 111.458 93.394  1.00 96.72 ? 336 THR A OG1 1 
ATOM   2362 C  CG2 . THR A 1 348 ? 108.678 111.411 91.125  1.00 96.72 ? 336 THR A CG2 1 
ATOM   2363 N  N   . SER A 1 349 ? 104.989 112.769 93.560  1.00 96.39 ? 337 SER A N   1 
ATOM   2364 C  CA  . SER A 1 349 ? 103.692 112.628 94.205  1.00 96.39 ? 337 SER A CA  1 
ATOM   2365 C  C   . SER A 1 349 ? 102.657 113.443 93.455  1.00 96.39 ? 337 SER A C   1 
ATOM   2366 O  O   . SER A 1 349 ? 101.536 112.988 93.247  1.00 96.39 ? 337 SER A O   1 
ATOM   2367 C  CB  . SER A 1 349 ? 103.775 113.103 95.653  1.00 96.39 ? 337 SER A CB  1 
ATOM   2368 O  OG  . SER A 1 349 ? 102.521 113.023 96.296  1.00 96.39 ? 337 SER A OG  1 
ATOM   2369 N  N   . PHE A 1 350 ? 103.033 114.644 93.033  1.00 96.65 ? 338 PHE A N   1 
ATOM   2370 C  CA  . PHE A 1 350 ? 102.107 115.513 92.322  1.00 96.65 ? 338 PHE A CA  1 
ATOM   2371 C  C   . PHE A 1 350 ? 101.791 114.933 90.951  1.00 96.65 ? 338 PHE A C   1 
ATOM   2372 O  O   . PHE A 1 350 ? 100.635 114.927 90.534  1.00 96.65 ? 338 PHE A O   1 
ATOM   2373 C  CB  . PHE A 1 350 ? 102.710 116.910 92.195  1.00 96.65 ? 338 PHE A CB  1 
ATOM   2374 C  CG  . PHE A 1 350 ? 101.700 117.998 91.991  1.00 96.65 ? 338 PHE A CG  1 
ATOM   2375 C  CD1 . PHE A 1 350 ? 100.586 118.088 92.802  1.00 96.65 ? 338 PHE A CD1 1 
ATOM   2376 C  CD2 . PHE A 1 350 ? 101.883 118.952 91.007  1.00 96.65 ? 338 PHE A CD2 1 
ATOM   2377 C  CE1 . PHE A 1 350 ? 99.656  119.092 92.619  1.00 96.65 ? 338 PHE A CE1 1 
ATOM   2378 C  CE2 . PHE A 1 350 ? 100.961 119.963 90.821  1.00 96.65 ? 338 PHE A CE2 1 
ATOM   2379 C  CZ  . PHE A 1 350 ? 99.845  120.033 91.628  1.00 96.65 ? 338 PHE A CZ  1 
ATOM   2380 N  N   . VAL A 1 351 ? 102.805 114.435 90.252  1.00 96.73 ? 339 VAL A N   1 
ATOM   2381 C  CA  . VAL A 1 351 ? 102.602 113.825 88.936  1.00 96.73 ? 339 VAL A CA  1 
ATOM   2382 C  C   . VAL A 1 351 ? 101.784 112.540 89.007  1.00 96.73 ? 339 VAL A C   1 
ATOM   2383 O  O   . VAL A 1 351 ? 100.892 112.319 88.189  1.00 96.73 ? 339 VAL A O   1 
ATOM   2384 C  CB  . VAL A 1 351 ? 103.952 113.568 88.240  1.00 96.73 ? 339 VAL A CB  1 
ATOM   2385 C  CG1 . VAL A 1 351 ? 103.793 112.664 87.027  1.00 96.73 ? 339 VAL A CG1 1 
ATOM   2386 C  CG2 . VAL A 1 351 ? 104.599 114.885 87.847  1.00 96.73 ? 339 VAL A CG2 1 
ATOM   2387 N  N   . SER A 1 352 ? 102.098 111.669 89.962  1.00 94.78 ? 340 SER A N   1 
ATOM   2388 C  CA  . SER A 1 352 ? 101.348 110.428 90.106  1.00 94.78 ? 340 SER A CA  1 
ATOM   2389 C  C   . SER A 1 352 ? 99.910  110.786 90.389  1.00 94.78 ? 340 SER A C   1 
ATOM   2390 O  O   . SER A 1 352 ? 98.991  110.088 89.965  1.00 94.78 ? 340 SER A O   1 
ATOM   2391 C  CB  . SER A 1 352 ? 101.909 109.563 91.229  1.00 94.78 ? 340 SER A CB  1 
ATOM   2392 O  OG  . SER A 1 352 ? 101.694 110.164 92.492  1.00 94.78 ? 340 SER A OG  1 
ATOM   2393 N  N   . GLY A 1 353 ? 99.707  111.892 91.091  1.00 94.46 ? 341 GLY A N   1 
ATOM   2394 C  CA  . GLY A 1 353 ? 98.361  112.333 91.381  1.00 94.46 ? 341 GLY A CA  1 
ATOM   2395 C  C   . GLY A 1 353 ? 97.601  112.666 90.117  1.00 94.46 ? 341 GLY A C   1 
ATOM   2396 O  O   . GLY A 1 353 ? 96.440  112.305 89.984  1.00 94.46 ? 341 GLY A O   1 
ATOM   2397 N  N   . PHE A 1 354 ? 98.249  113.325 89.166  1.00 96.39 ? 342 PHE A N   1 
ATOM   2398 C  CA  . PHE A 1 354 ? 97.540  113.730 87.965  1.00 96.39 ? 342 PHE A CA  1 
ATOM   2399 C  C   . PHE A 1 354 ? 97.038  112.506 87.235  1.00 96.39 ? 342 PHE A C   1 
ATOM   2400 O  O   . PHE A 1 354 ? 95.902  112.476 86.774  1.00 96.39 ? 342 PHE A O   1 
ATOM   2401 C  CB  . PHE A 1 354 ? 98.443  114.521 87.025  1.00 96.39 ? 342 PHE A CB  1 
ATOM   2402 C  CG  . PHE A 1 354 ? 98.575  115.968 87.382  1.00 96.39 ? 342 PHE A CG  1 
ATOM   2403 C  CD1 . PHE A 1 354 ? 97.493  116.821 87.270  1.00 96.39 ? 342 PHE A CD1 1 
ATOM   2404 C  CD2 . PHE A 1 354 ? 99.787  116.480 87.805  1.00 96.39 ? 342 PHE A CD2 1 
ATOM   2405 C  CE1 . PHE A 1 354 ? 97.613  118.157 87.592  1.00 96.39 ? 342 PHE A CE1 1 
ATOM   2406 C  CE2 . PHE A 1 354 ? 99.914  117.815 88.127  1.00 96.39 ? 342 PHE A CE2 1 
ATOM   2407 C  CZ  . PHE A 1 354 ? 98.825  118.656 88.021  1.00 96.39 ? 342 PHE A CZ  1 
ATOM   2408 N  N   . ALA A 1 355 ? 97.878  111.485 87.142  1.00 93.17 ? 343 ALA A N   1 
ATOM   2409 C  CA  . ALA A 1 355 ? 97.480  110.285 86.439  1.00 93.17 ? 343 ALA A CA  1 
ATOM   2410 C  C   . ALA A 1 355 ? 96.313  109.604 87.128  1.00 93.17 ? 343 ALA A C   1 
ATOM   2411 O  O   . ALA A 1 355 ? 95.339  109.248 86.479  1.00 93.17 ? 343 ALA A O   1 
ATOM   2412 C  CB  . ALA A 1 355 ? 98.654  109.335 86.324  1.00 93.17 ? 343 ALA A CB  1 
ATOM   2413 N  N   . ILE A 1 356 ? 96.374  109.474 88.450  1.00 90.75 ? 344 ILE A N   1 
ATOM   2414 C  CA  . ILE A 1 356 ? 95.314  108.768 89.154  1.00 90.75 ? 344 ILE A CA  1 
ATOM   2415 C  C   . ILE A 1 356 ? 94.006  109.508 88.983  1.00 90.75 ? 344 ILE A C   1 
ATOM   2416 O  O   . ILE A 1 356 ? 92.988  108.909 88.641  1.00 90.75 ? 344 ILE A O   1 
ATOM   2417 C  CB  . ILE A 1 356 ? 95.632  108.643 90.656  1.00 90.75 ? 344 ILE A CB  1 
ATOM   2418 C  CG1 . ILE A 1 356 ? 96.514  107.431 90.917  1.00 90.75 ? 344 ILE A CG1 1 
ATOM   2419 C  CG2 . ILE A 1 356 ? 94.365  108.464 91.470  1.00 90.75 ? 344 ILE A CG2 1 
ATOM   2420 C  CD1 . ILE A 1 356 ? 95.738  106.134 90.960  1.00 90.75 ? 344 ILE A CD1 1 
ATOM   2421 N  N   . PHE A 1 357 ? 94.040  110.821 89.161  1.00 92.56 ? 345 PHE A N   1 
ATOM   2422 C  CA  . PHE A 1 357 ? 92.823  111.613 89.052  1.00 92.56 ? 345 PHE A CA  1 
ATOM   2423 C  C   . PHE A 1 357 ? 92.228  111.685 87.655  1.00 92.56 ? 345 PHE A C   1 
ATOM   2424 O  O   . PHE A 1 357 ? 91.013  111.668 87.502  1.00 92.56 ? 345 PHE A O   1 
ATOM   2425 C  CB  . PHE A 1 357 ? 92.966  112.959 89.752  1.00 92.56 ? 345 PHE A CB  1 
ATOM   2426 C  CG  . PHE A 1 357 ? 92.969  112.839 91.250  1.00 92.56 ? 345 PHE A CG  1 
ATOM   2427 C  CD1 . PHE A 1 357 ? 91.781  112.765 91.949  1.00 92.56 ? 345 PHE A CD1 1 
ATOM   2428 C  CD2 . PHE A 1 357 ? 94.156  112.746 91.953  1.00 92.56 ? 345 PHE A CD2 1 
ATOM   2429 C  CE1 . PHE A 1 357 ? 91.778  112.631 93.323  1.00 92.56 ? 345 PHE A CE1 1 
ATOM   2430 C  CE2 . PHE A 1 357 ? 94.162  112.612 93.326  1.00 92.56 ? 345 PHE A CE2 1 
ATOM   2431 C  CZ  . PHE A 1 357 ? 92.969  112.556 94.013  1.00 92.56 ? 345 PHE A CZ  1 
ATOM   2432 N  N   . SER A 1 358 ? 93.070  111.762 86.634  1.00 94.36 ? 346 SER A N   1 
ATOM   2433 C  CA  . SER A 1 358 ? 92.559  111.756 85.272  1.00 94.36 ? 346 SER A CA  1 
ATOM   2434 C  C   . SER A 1 358 ? 91.849  110.445 84.968  1.00 94.36 ? 346 SER A C   1 
ATOM   2435 O  O   . SER A 1 358 ? 90.811  110.440 84.311  1.00 94.36 ? 346 SER A O   1 
ATOM   2436 C  CB  . SER A 1 358 ? 93.680  112.009 84.273  1.00 94.36 ? 346 SER A CB  1 
ATOM   2437 O  OG  . SER A 1 358 ? 94.738  111.088 84.445  1.00 94.36 ? 346 SER A OG  1 
ATOM   2438 N  N   . ILE A 1 359 ? 92.401  109.330 85.435  1.00 90.52 ? 347 ILE A N   1 
ATOM   2439 C  CA  . ILE A 1 359 ? 91.754  108.033 85.242  1.00 90.52 ? 347 ILE A CA  1 
ATOM   2440 C  C   . ILE A 1 359 ? 90.420  108.007 85.967  1.00 90.52 ? 347 ILE A C   1 
ATOM   2441 O  O   . ILE A 1 359 ? 89.440  107.486 85.449  1.00 90.52 ? 347 ILE A O   1 
ATOM   2442 C  CB  . ILE A 1 359 ? 92.648  106.879 85.724  1.00 90.52 ? 347 ILE A CB  1 
ATOM   2443 C  CG1 . ILE A 1 359 ? 93.936  106.848 84.911  1.00 90.52 ? 347 ILE A CG1 1 
ATOM   2444 C  CG2 . ILE A 1 359 ? 91.941  105.541 85.584  1.00 90.52 ? 347 ILE A CG2 1 
ATOM   2445 C  CD1 . ILE A 1 359 ? 95.039  106.064 85.575  1.00 90.52 ? 347 ILE A CD1 1 
ATOM   2446 N  N   . LEU A 1 360 ? 90.371  108.586 87.160  1.00 89.48 ? 348 LEU A N   1 
ATOM   2447 C  CA  . LEU A 1 360 ? 89.120  108.648 87.907  1.00 89.48 ? 348 LEU A CA  1 
ATOM   2448 C  C   . LEU A 1 360 ? 88.099  109.449 87.134  1.00 89.48 ? 348 LEU A C   1 
ATOM   2449 O  O   . LEU A 1 360 ? 86.923  109.120 87.147  1.00 89.48 ? 348 LEU A O   1 
ATOM   2450 C  CB  . LEU A 1 360 ? 89.330  109.258 89.287  1.00 89.48 ? 348 LEU A CB  1 
ATOM   2451 C  CG  . LEU A 1 360 ? 90.117  108.393 90.261  1.00 89.48 ? 348 LEU A CG  1 
ATOM   2452 C  CD1 . LEU A 1 360 ? 90.305  109.135 91.571  1.00 89.48 ? 348 LEU A CD1 1 
ATOM   2453 C  CD2 . LEU A 1 360 ? 89.384  107.082 90.471  1.00 89.48 ? 348 LEU A CD2 1 
ATOM   2454 N  N   . GLY A 1 361 ? 88.534  110.517 86.482  1.00 92.61 ? 349 GLY A N   1 
ATOM   2455 C  CA  . GLY A 1 361 ? 87.628  111.294 85.658  1.00 92.61 ? 349 GLY A CA  1 
ATOM   2456 C  C   . GLY A 1 361 ? 87.086  110.477 84.510  1.00 92.61 ? 349 GLY A C   1 
ATOM   2457 O  O   . GLY A 1 361 ? 85.910  110.586 84.175  1.00 92.61 ? 349 GLY A O   1 
ATOM   2458 N  N   . PHE A 1 362 ? 87.918  109.617 83.935  1.00 90.04 ? 350 PHE A N   1 
ATOM   2459 C  CA  . PHE A 1 362 ? 87.463  108.734 82.865  1.00 90.04 ? 350 PHE A CA  1 
ATOM   2460 C  C   . PHE A 1 362 ? 86.472  107.724 83.411  1.00 90.04 ? 350 PHE A C   1 
ATOM   2461 O  O   . PHE A 1 362 ? 85.428  107.479 82.807  1.00 90.04 ? 350 PHE A O   1 
ATOM   2462 C  CB  . PHE A 1 362 ? 88.658  108.010 82.248  1.00 90.04 ? 350 PHE A CB  1 
ATOM   2463 C  CG  . PHE A 1 362 ? 88.283  106.948 81.261  1.00 90.04 ? 350 PHE A CG  1 
ATOM   2464 C  CD1 . PHE A 1 362 ? 87.631  107.274 80.086  1.00 90.04 ? 350 PHE A CD1 1 
ATOM   2465 C  CD2 . PHE A 1 362 ? 88.595  105.624 81.502  1.00 90.04 ? 350 PHE A CD2 1 
ATOM   2466 C  CE1 . PHE A 1 362 ? 87.287  106.301 79.173  1.00 90.04 ? 350 PHE A CE1 1 
ATOM   2467 C  CE2 . PHE A 1 362 ? 88.257  104.645 80.592  1.00 90.04 ? 350 PHE A CE2 1 
ATOM   2468 C  CZ  . PHE A 1 362 ? 87.605  104.985 79.425  1.00 90.04 ? 350 PHE A CZ  1 
ATOM   2469 N  N   . MET A 1 363 ? 86.789  107.143 84.563  1.00 87.27 ? 351 MET A N   1 
ATOM   2470 C  CA  . MET A 1 363 ? 85.901  106.165 85.170  1.00 87.27 ? 351 MET A CA  1 
ATOM   2471 C  C   . MET A 1 363 ? 84.586  106.835 85.497  1.00 87.27 ? 351 MET A C   1 
ATOM   2472 O  O   . MET A 1 363 ? 83.529  106.256 85.294  1.00 87.27 ? 351 MET A O   1 
ATOM   2473 C  CB  . MET A 1 363 ? 86.517  105.581 86.439  1.00 87.27 ? 351 MET A CB  1 
ATOM   2474 C  CG  . MET A 1 363 ? 87.719  104.688 86.195  1.00 87.27 ? 351 MET A CG  1 
ATOM   2475 S  SD  . MET A 1 363 ? 88.567  104.238 87.720  1.00 87.27 ? 351 MET A SD  1 
ATOM   2476 C  CE  . MET A 1 363 ? 87.231  103.491 88.646  1.00 87.27 ? 351 MET A CE  1 
ATOM   2477 N  N   . ALA A 1 364 ? 84.647  108.068 85.981  1.00 87.99 ? 352 ALA A N   1 
ATOM   2478 C  CA  . ALA A 1 364 ? 83.435  108.774 86.353  1.00 87.99 ? 352 ALA A CA  1 
ATOM   2479 C  C   . ALA A 1 364 ? 82.538  108.964 85.149  1.00 87.99 ? 352 ALA A C   1 
ATOM   2480 O  O   . ALA A 1 364 ? 81.326  108.818 85.255  1.00 87.99 ? 352 ALA A O   1 
ATOM   2481 C  CB  . ALA A 1 364 ? 83.773  110.117 86.972  1.00 87.99 ? 352 ALA A CB  1 
ATOM   2482 N  N   . GLN A 1 365 ? 83.142  109.291 84.014  1.00 88.30 ? 353 GLN A N   1 
ATOM   2483 C  CA  . GLN A 1 365 ? 82.381  109.491 82.790  1.00 88.30 ? 353 GLN A CA  1 
ATOM   2484 C  C   . GLN A 1 365 ? 81.624  108.224 82.428  1.00 88.30 ? 353 GLN A C   1 
ATOM   2485 O  O   . GLN A 1 365 ? 80.402  108.242 82.290  1.00 88.30 ? 353 GLN A O   1 
ATOM   2486 C  CB  . GLN A 1 365 ? 83.332  109.875 81.661  1.00 88.30 ? 353 GLN A CB  1 
ATOM   2487 C  CG  . GLN A 1 365 ? 82.662  110.219 80.345  1.00 88.30 ? 353 GLN A CG  1 
ATOM   2488 C  CD  . GLN A 1 365 ? 83.648  110.229 79.195  1.00 88.30 ? 353 GLN A CD  1 
ATOM   2489 O  OE1 . GLN A 1 365 ? 83.329  110.665 78.090  1.00 88.30 ? 353 GLN A OE1 1 
ATOM   2490 N  NE2 . GLN A 1 365 ? 84.856  109.745 79.453  1.00 88.30 ? 353 GLN A NE2 1 
ATOM   2491 N  N   . GLU A 1 366 ? 82.346  107.120 82.269  1.00 83.63 ? 354 GLU A N   1 
ATOM   2492 C  CA  . GLU A 1 366 ? 81.699  105.877 81.876  1.00 83.63 ? 354 GLU A CA  1 
ATOM   2493 C  C   . GLU A 1 366 ? 80.697  105.355 82.895  1.00 83.63 ? 354 GLU A C   1 
ATOM   2494 O  O   . GLU A 1 366 ? 79.590  104.967 82.539  1.00 83.63 ? 354 GLU A O   1 
ATOM   2495 C  CB  . GLU A 1 366 ? 82.751  104.805 81.607  1.00 83.63 ? 354 GLU A CB  1 
ATOM   2496 C  CG  . GLU A 1 366 ? 83.504  104.999 80.305  1.00 83.63 ? 354 GLU A CG  1 
ATOM   2497 C  CD  . GLU A 1 366 ? 84.378  103.812 79.965  1.00 83.63 ? 354 GLU A CD  1 
ATOM   2498 O  OE1 . GLU A 1 366 ? 84.611  103.570 78.763  1.00 83.63 ? 354 GLU A OE1 1 
ATOM   2499 O  OE2 . GLU A 1 366 ? 84.824  103.116 80.901  1.00 83.63 ? 354 GLU A OE2 1 
ATOM   2500 N  N   . GLN A 1 367 ? 81.072  105.357 84.165  1.00 81.43 ? 355 GLN A N   1 
ATOM   2501 C  CA  . GLN A 1 367 ? 80.164  104.902 85.210  1.00 81.43 ? 355 GLN A CA  1 
ATOM   2502 C  C   . GLN A 1 367 ? 78.957  105.812 85.371  1.00 81.43 ? 355 GLN A C   1 
ATOM   2503 O  O   . GLN A 1 367 ? 77.846  105.339 85.600  1.00 81.43 ? 355 GLN A O   1 
ATOM   2504 C  CB  . GLN A 1 367 ? 80.912  104.701 86.527  1.00 81.43 ? 355 GLN A CB  1 
ATOM   2505 C  CG  . GLN A 1 367 ? 81.923  103.567 86.468  1.00 81.43 ? 355 GLN A CG  1 
ATOM   2506 C  CD  . GLN A 1 367 ? 82.679  103.387 87.767  1.00 81.43 ? 355 GLN A CD  1 
ATOM   2507 O  OE1 . GLN A 1 367 ? 83.754  102.789 87.793  1.00 81.43 ? 355 GLN A OE1 1 
ATOM   2508 N  NE2 . GLN A 1 367 ? 82.123  103.908 88.853  1.00 81.43 ? 355 GLN A NE2 1 
ATOM   2509 N  N   . GLY A 1 368 ? 79.166  107.117 85.248  1.00 81.31 ? 356 GLY A N   1 
ATOM   2510 C  CA  . GLY A 1 368 ? 78.087  108.072 85.442  1.00 81.31 ? 356 GLY A CA  1 
ATOM   2511 C  C   . GLY A 1 368 ? 78.017  108.543 86.878  1.00 81.31 ? 356 GLY A C   1 
ATOM   2512 O  O   . GLY A 1 368 ? 77.229  109.429 87.205  1.00 81.31 ? 356 GLY A O   1 
ATOM   2513 N  N   . VAL A 1 369 ? 78.837  107.961 87.745  1.00 83.01 ? 357 VAL A N   1 
ATOM   2514 C  CA  . VAL A 1 369 ? 78.885  108.390 89.137  1.00 83.01 ? 357 VAL A CA  1 
ATOM   2515 C  C   . VAL A 1 369 ? 79.732  109.643 89.270  1.00 83.01 ? 357 VAL A C   1 
ATOM   2516 O  O   . VAL A 1 369 ? 80.536  109.945 88.390  1.00 83.01 ? 357 VAL A O   1 
ATOM   2517 C  CB  . VAL A 1 369 ? 79.463  107.290 90.048  1.00 83.01 ? 357 VAL A CB  1 
ATOM   2518 C  CG1 . VAL A 1 369 ? 79.619  107.799 91.472  1.00 83.01 ? 357 VAL A CG1 1 
ATOM   2519 C  CG2 . VAL A 1 369 ? 78.550  106.081 90.046  1.00 83.01 ? 357 VAL A CG2 1 
ATOM   2520 N  N   . ASP A 1 370 ? 79.589  110.367 90.376  1.00 85.48 ? 358 ASP A N   1 
ATOM   2521 C  CA  . ASP A 1 370 ? 80.424  111.540 90.615  1.00 85.48 ? 358 ASP A CA  1 
ATOM   2522 C  C   . ASP A 1 370 ? 81.852  111.091 90.865  1.00 85.48 ? 358 ASP A C   1 
ATOM   2523 O  O   . ASP A 1 370 ? 82.085  109.958 91.278  1.00 85.48 ? 358 ASP A O   1 
ATOM   2524 C  CB  . ASP A 1 370 ? 79.915  112.312 91.827  1.00 85.48 ? 358 ASP A CB  1 
ATOM   2525 C  CG  . ASP A 1 370 ? 78.493  112.798 91.652  1.00 85.48 ? 358 ASP A CG  1 
ATOM   2526 O  OD1 . ASP A 1 370 ? 77.992  112.785 90.508  1.00 85.48 ? 358 ASP A OD1 1 
ATOM   2527 O  OD2 . ASP A 1 370 ? 77.875  113.200 92.660  1.00 85.48 ? 358 ASP A OD2 1 
ATOM   2528 N  N   . ILE A 1 371 ? 82.810  111.985 90.661  1.00 84.36 ? 359 ILE A N   1 
ATOM   2529 C  CA  . ILE A 1 371 ? 84.211  111.622 90.835  1.00 84.36 ? 359 ILE A CA  1 
ATOM   2530 C  C   . ILE A 1 371 ? 84.497  111.203 92.273  1.00 84.36 ? 359 ILE A C   1 
ATOM   2531 O  O   . ILE A 1 371 ? 85.289  110.309 92.507  1.00 84.36 ? 359 ILE A O   1 
ATOM   2532 C  CB  . ILE A 1 371 ? 85.183  112.717 90.343  1.00 84.36 ? 359 ILE A CB  1 
ATOM   2533 C  CG1 . ILE A 1 371 ? 86.631  112.247 90.497  1.00 84.36 ? 359 ILE A CG1 1 
ATOM   2534 C  CG2 . ILE A 1 371 ? 84.944  114.035 91.064  1.00 84.36 ? 359 ILE A CG2 1 
ATOM   2535 C  CD1 . ILE A 1 371 ? 87.637  113.114 89.789  1.00 84.36 ? 359 ILE A CD1 1 
ATOM   2536 N  N   . ALA A 1 372 ? 83.850  111.842 93.237  1.00 81.38 ? 360 ALA A N   1 
ATOM   2537 C  CA  . ALA A 1 372 ? 84.069  111.514 94.641  1.00 81.38 ? 360 ALA A CA  1 
ATOM   2538 C  C   . ALA A 1 372 ? 83.692  110.079 94.988  1.00 81.38 ? 360 ALA A C   1 
ATOM   2539 O  O   . ALA A 1 372 ? 84.350  109.449 95.811  1.00 81.38 ? 360 ALA A O   1 
ATOM   2540 C  CB  . ALA A 1 372 ? 83.307  112.482 95.527  1.00 81.38 ? 360 ALA A CB  1 
ATOM   2541 N  N   . ASP A 1 373 ? 82.612  109.572 94.405  1.00 77.78 ? 361 ASP A N   1 
ATOM   2542 C  CA  . ASP A 1 373 ? 82.147  108.222 94.730  1.00 77.78 ? 361 ASP A CA  1 
ATOM   2543 C  C   . ASP A 1 373 ? 82.611  107.061 93.838  1.00 77.78 ? 361 ASP A C   1 
ATOM   2544 O  O   . ASP A 1 373 ? 82.258  105.917 94.111  1.00 77.78 ? 361 ASP A O   1 
ATOM   2545 C  CB  . ASP A 1 373 ? 80.620  108.218 94.794  1.00 77.78 ? 361 ASP A CB  1 
ATOM   2546 C  CG  . ASP A 1 373 ? 80.076  109.234 95.774  1.00 77.78 ? 361 ASP A CG  1 
ATOM   2547 O  OD1 . ASP A 1 373 ? 80.810  109.613 96.710  1.00 77.78 ? 361 ASP A OD1 1 
ATOM   2548 O  OD2 . ASP A 1 373 ? 78.915  109.659 95.604  1.00 77.78 ? 361 ASP A OD2 1 
ATOM   2549 N  N   . VAL A 1 374 ? 83.354  107.324 92.764  1.00 75.80 ? 362 VAL A N   1 
ATOM   2550 C  CA  . VAL A 1 374 ? 83.715  106.238 91.833  1.00 75.80 ? 362 VAL A CA  1 
ATOM   2551 C  C   . VAL A 1 374 ? 84.701  105.206 92.356  1.00 75.80 ? 362 VAL A C   1 
ATOM   2552 O  O   . VAL A 1 374 ? 84.832  104.134 91.771  1.00 75.80 ? 362 VAL A O   1 
ATOM   2553 C  CB  . VAL A 1 374 ? 84.249  106.749 90.480  1.00 75.80 ? 362 VAL A CB  1 
ATOM   2554 C  CG1 . VAL A 1 374 ? 83.142  107.389 89.671  1.00 75.80 ? 362 VAL A CG1 1 
ATOM   2555 C  CG2 . VAL A 1 374 ? 85.433  107.681 90.660  1.00 75.80 ? 362 VAL A CG2 1 
ATOM   2556 N  N   . ALA A 1 375 ? 85.403  105.495 93.436  1.00 66.23 ? 363 ALA A N   1 
ATOM   2557 C  CA  . ALA A 1 375 ? 86.385  104.542 93.908  1.00 66.23 ? 363 ALA A CA  1 
ATOM   2558 C  C   . ALA A 1 375 ? 86.389  104.489 95.413  1.00 66.23 ? 363 ALA A C   1 
ATOM   2559 O  O   . ALA A 1 375 ? 85.738  105.297 96.073  1.00 66.23 ? 363 ALA A O   1 
ATOM   2560 C  CB  . ALA A 1 375 ? 87.760  104.890 93.383  1.00 66.23 ? 363 ALA A CB  1 
ATOM   2561 N  N   . GLU A 1 376 ? 87.110  103.528 95.965  1.00 62.43 ? 364 GLU A N   1 
ATOM   2562 C  CA  . GLU A 1 376 ? 87.188  103.425 97.402  1.00 62.43 ? 364 GLU A CA  1 
ATOM   2563 C  C   . GLU A 1 376 ? 87.940  104.620 97.935  1.00 62.43 ? 364 GLU A C   1 
ATOM   2564 O  O   . GLU A 1 376 ? 89.014  104.948 97.435  1.00 62.43 ? 364 GLU A O   1 
ATOM   2565 C  CB  . GLU A 1 376 ? 87.912  102.137 97.784  1.00 62.43 ? 364 GLU A CB  1 
ATOM   2566 C  CG  . GLU A 1 376 ? 88.323  102.050 99.241  1.00 62.43 ? 364 GLU A CG  1 
ATOM   2567 C  CD  . GLU A 1 376 ? 89.159  100.826 99.528  1.00 62.43 ? 364 GLU A CD  1 
ATOM   2568 O  OE1 . GLU A 1 376 ? 88.957  99.796  98.853  1.00 62.43 ? 364 GLU A OE1 1 
ATOM   2569 O  OE2 . GLU A 1 376 ? 90.011  100.892 100.434 1.00 62.43 ? 364 GLU A OE2 1 
ATOM   2570 N  N   . SER A 1 377 ? 87.401  105.273 98.957  1.00 54.93 ? 365 SER A N   1 
ATOM   2571 C  CA  . SER A 1 377 ? 88.116  106.368 99.581  1.00 54.93 ? 365 SER A CA  1 
ATOM   2572 C  C   . SER A 1 377 ? 88.959  105.669 100.602 1.00 54.93 ? 365 SER A C   1 
ATOM   2573 O  O   . SER A 1 377 ? 88.562  105.532 101.755 1.00 54.93 ? 365 SER A O   1 
ATOM   2574 C  CB  . SER A 1 377 ? 87.148  107.326 100.253 1.00 54.93 ? 365 SER A CB  1 
ATOM   2575 O  OG  . SER A 1 377 ? 86.183  107.797 99.330  1.00 54.93 ? 365 SER A OG  1 
ATOM   2576 N  N   . GLY A 1 378 ? 90.106  105.161 100.173 1.00 61.11 ? 366 GLY A N   1 
ATOM   2577 C  CA  . GLY A 1 378 ? 90.958  104.411 101.070 1.00 61.11 ? 366 GLY A CA  1 
ATOM   2578 C  C   . GLY A 1 378 ? 92.145  103.876 100.313 1.00 61.11 ? 366 GLY A C   1 
ATOM   2579 O  O   . GLY A 1 378 ? 92.391  104.310 99.193  1.00 61.11 ? 366 GLY A O   1 
ATOM   2580 N  N   . PRO A 1 379 ? 92.858  102.897 100.880 1.00 63.48 ? 367 PRO A N   1 
ATOM   2581 C  CA  . PRO A 1 379 ? 94.075  102.354 100.265 1.00 63.48 ? 367 PRO A CA  1 
ATOM   2582 C  C   . PRO A 1 379 ? 93.841  101.658 98.939  1.00 63.48 ? 367 PRO A C   1 
ATOM   2583 O  O   . PRO A 1 379 ? 94.768  101.505 98.152  1.00 63.48 ? 367 PRO A O   1 
ATOM   2584 C  CB  . PRO A 1 379 ? 94.578  101.372 101.320 1.00 63.48 ? 367 PRO A CB  1 
ATOM   2585 C  CG  . PRO A 1 379 ? 94.013  101.884 102.600 1.00 63.48 ? 367 PRO A CG  1 
ATOM   2586 C  CD  . PRO A 1 379 ? 92.637  102.330 102.212 1.00 63.48 ? 367 PRO A CD  1 
ATOM   2587 N  N   . GLY A 1 380 ? 92.618  101.231 98.692  1.00 70.85 ? 368 GLY A N   1 
ATOM   2588 C  CA  . GLY A 1 380 ? 92.296  100.565 97.452  1.00 70.85 ? 368 GLY A CA  1 
ATOM   2589 C  C   . GLY A 1 380 ? 92.386  101.418 96.209  1.00 70.85 ? 368 GLY A C   1 
ATOM   2590 O  O   . GLY A 1 380 ? 92.402  100.876 95.115  1.00 70.85 ? 368 GLY A O   1 
ATOM   2591 N  N   . LEU A 1 381 ? 92.450  102.737 96.343  1.00 74.66 ? 369 LEU A N   1 
ATOM   2592 C  CA  . LEU A 1 381 ? 92.414  103.597 95.161  1.00 74.66 ? 369 LEU A CA  1 
ATOM   2593 C  C   . LEU A 1 381 ? 93.537  103.364 94.140  1.00 74.66 ? 369 LEU A C   1 
ATOM   2594 O  O   . LEU A 1 381 ? 93.271  103.313 92.943  1.00 74.66 ? 369 LEU A O   1 
ATOM   2595 C  CB  . LEU A 1 381 ? 92.413  105.066 95.590  1.00 74.66 ? 369 LEU A CB  1 
ATOM   2596 C  CG  . LEU A 1 381 ? 92.393  106.105 94.472  1.00 74.66 ? 369 LEU A CG  1 
ATOM   2597 C  CD1 . LEU A 1 381 ? 91.106  105.997 93.680  1.00 74.66 ? 369 LEU A CD1 1 
ATOM   2598 C  CD2 . LEU A 1 381 ? 92.542  107.503 95.034  1.00 74.66 ? 369 LEU A CD2 1 
ATOM   2599 N  N   . ALA A 1 382 ? 94.774  103.188 94.584  1.00 85.85 ? 370 ALA A N   1 
ATOM   2600 C  CA  . ALA A 1 382 ? 95.843  102.898 93.635  1.00 85.85 ? 370 ALA A CA  1 
ATOM   2601 C  C   . ALA A 1 382 ? 95.578  101.577 92.943  1.00 85.85 ? 370 ALA A C   1 
ATOM   2602 O  O   . ALA A 1 382 ? 95.845  101.432 91.754  1.00 85.85 ? 370 ALA A O   1 
ATOM   2603 C  CB  . ALA A 1 382 ? 97.183  102.866 94.335  1.00 85.85 ? 370 ALA A CB  1 
ATOM   2604 N  N   . PHE A 1 383 ? 95.054  100.610 93.684  1.00 91.78 ? 371 PHE A N   1 
ATOM   2605 C  CA  . PHE A 1 383 ? 94.744  99.301  93.122  1.00 91.78 ? 371 PHE A CA  1 
ATOM   2606 C  C   . PHE A 1 383 ? 93.428  99.243  92.369  1.00 91.78 ? 371 PHE A C   1 
ATOM   2607 O  O   . PHE A 1 383 ? 93.121  98.230  91.752  1.00 91.78 ? 371 PHE A O   1 
ATOM   2608 C  CB  . PHE A 1 383 ? 94.803  98.225  94.199  1.00 91.78 ? 371 PHE A CB  1 
ATOM   2609 C  CG  . PHE A 1 383 ? 96.183  97.989  94.734  1.00 91.78 ? 371 PHE A CG  1 
ATOM   2610 C  CD1 . PHE A 1 383 ? 97.134  97.347  93.962  1.00 91.78 ? 371 PHE A CD1 1 
ATOM   2611 C  CD2 . PHE A 1 383 ? 96.532  98.410  96.002  1.00 91.78 ? 371 PHE A CD2 1 
ATOM   2612 C  CE1 . PHE A 1 383 ? 98.406  97.125  94.445  1.00 91.78 ? 371 PHE A CE1 1 
ATOM   2613 C  CE2 . PHE A 1 383 ? 97.803  98.193  96.493  1.00 91.78 ? 371 PHE A CE2 1 
ATOM   2614 C  CZ  . PHE A 1 383 ? 98.742  97.549  95.714  1.00 91.78 ? 371 PHE A CZ  1 
ATOM   2615 N  N   . ILE A 1 384 ? 92.650  100.318 92.401  1.00 89.21 ? 372 ILE A N   1 
ATOM   2616 C  CA  . ILE A 1 384 ? 91.420  100.353 91.612  1.00 89.21 ? 372 ILE A CA  1 
ATOM   2617 C  C   . ILE A 1 384 ? 91.625  101.189 90.346  1.00 89.21 ? 372 ILE A C   1 
ATOM   2618 O  O   . ILE A 1 384 ? 91.445  100.690 89.237  1.00 89.21 ? 372 ILE A O   1 
ATOM   2619 C  CB  . ILE A 1 384 ? 90.205  100.833 92.432  1.00 89.21 ? 372 ILE A CB  1 
ATOM   2620 C  CG1 . ILE A 1 384 ? 89.804  99.764  93.447  1.00 89.21 ? 372 ILE A CG1 1 
ATOM   2621 C  CG2 . ILE A 1 384 ? 89.018  101.122 91.529  1.00 89.21 ? 372 ILE A CG2 1 
ATOM   2622 C  CD1 . ILE A 1 384 ? 88.639  100.161 94.323  1.00 89.21 ? 372 ILE A CD1 1 
ATOM   2623 N  N   . ALA A 1 385 ? 92.060  102.434 90.504  1.00 84.57 ? 373 ALA A N   1 
ATOM   2624 C  CA  . ALA A 1 385 ? 92.251  103.320 89.355  1.00 84.57 ? 373 ALA A CA  1 
ATOM   2625 C  C   . ALA A 1 385 ? 93.277  102.833 88.348  1.00 84.57 ? 373 ALA A C   1 
ATOM   2626 O  O   . ALA A 1 385 ? 92.981  102.732 87.166  1.00 84.57 ? 373 ALA A O   1 
ATOM   2627 C  CB  . ALA A 1 385 ? 92.612  104.715 89.824  1.00 84.57 ? 373 ALA A CB  1 
ATOM   2628 N  N   . TYR A 1 386 ? 94.503  102.582 88.790  1.00 85.36 ? 374 TYR A N   1 
ATOM   2629 C  CA  . TYR A 1 386 ? 95.567  102.194 87.854  1.00 85.36 ? 374 TYR A CA  1 
ATOM   2630 C  C   . TYR A 1 386 ? 95.322  100.926 87.030  1.00 85.36 ? 374 TYR A C   1 
ATOM   2631 O  O   . TYR A 1 386 ? 95.656  100.895 85.850  1.00 85.36 ? 374 TYR A O   1 
ATOM   2632 C  CB  . TYR A 1 386 ? 96.926  102.149 88.547  1.00 85.36 ? 374 TYR A CB  1 
ATOM   2633 C  CG  . TYR A 1 386 ? 97.641  103.478 88.627  1.00 85.36 ? 374 TYR A CG  1 
ATOM   2634 C  CD1 . TYR A 1 386 ? 97.622  104.363 87.561  1.00 85.36 ? 374 TYR A CD1 1 
ATOM   2635 C  CD2 . TYR A 1 386 ? 98.360  103.833 89.758  1.00 85.36 ? 374 TYR A CD2 1 
ATOM   2636 C  CE1 . TYR A 1 386 ? 98.282  105.575 87.628  1.00 85.36 ? 374 TYR A CE1 1 
ATOM   2637 C  CE2 . TYR A 1 386 ? 99.031  105.036 89.830  1.00 85.36 ? 374 TYR A CE2 1 
ATOM   2638 C  CZ  . TYR A 1 386 ? 98.986  105.904 88.763  1.00 85.36 ? 374 TYR A CZ  1 
ATOM   2639 O  OH  . TYR A 1 386 ? 99.647  107.106 88.837  1.00 85.36 ? 374 TYR A OH  1 
ATOM   2640 N  N   . PRO A 1 387 ? 94.748  99.872  87.634  1.00 91.24 ? 375 PRO A N   1 
ATOM   2641 C  CA  . PRO A 1 387 ? 94.417  98.711  86.802  1.00 91.24 ? 375 PRO A CA  1 
ATOM   2642 C  C   . PRO A 1 387 ? 93.414  99.041  85.696  1.00 91.24 ? 375 PRO A C   1 
ATOM   2643 O  O   . PRO A 1 387 ? 93.509  98.461  84.619  1.00 91.24 ? 375 PRO A O   1 
ATOM   2644 C  CB  . PRO A 1 387 ? 93.829  97.736  87.811  1.00 91.24 ? 375 PRO A CB  1 
ATOM   2645 C  CG  . PRO A 1 387 ? 94.661  97.985  89.011  1.00 91.24 ? 375 PRO A CG  1 
ATOM   2646 C  CD  . PRO A 1 387 ? 94.813  99.482  89.055  1.00 91.24 ? 375 PRO A CD  1 
ATOM   2647 N  N   . LYS A 1 388 ? 92.495  99.969  85.947  1.00 89.23 ? 376 LYS A N   1 
ATOM   2648 C  CA  . LYS A 1 388 ? 91.534  100.369 84.923  1.00 89.23 ? 376 LYS A CA  1 
ATOM   2649 C  C   . LYS A 1 388 ? 92.266  101.024 83.764  1.00 89.23 ? 376 LYS A C   1 
ATOM   2650 O  O   . LYS A 1 388 ? 91.902  100.829 82.609  1.00 89.23 ? 376 LYS A O   1 
ATOM   2651 C  CB  . LYS A 1 388 ? 90.482  101.318 85.497  1.00 89.23 ? 376 LYS A CB  1 
ATOM   2652 C  CG  . LYS A 1 388 ? 89.103  101.199 84.867  1.00 89.23 ? 376 LYS A CG  1 
ATOM   2653 C  CD  . LYS A 1 388 ? 88.981  102.023 83.596  1.00 89.23 ? 376 LYS A CD  1 
ATOM   2654 C  CE  . LYS A 1 388 ? 87.617  101.842 82.955  1.00 89.23 ? 376 LYS A CE  1 
ATOM   2655 N  NZ  . LYS A 1 388 ? 87.322  100.409 82.677  1.00 89.23 ? 376 LYS A NZ  1 
ATOM   2656 N  N   . ALA A 1 389 ? 93.310  101.788 84.063  1.00 86.25 ? 377 ALA A N   1 
ATOM   2657 C  CA  . ALA A 1 389 ? 94.094  102.411 83.004  1.00 86.25 ? 377 ALA A CA  1 
ATOM   2658 C  C   . ALA A 1 389 ? 94.727  101.344 82.150  1.00 86.25 ? 377 ALA A C   1 
ATOM   2659 O  O   . ALA A 1 389 ? 94.770  101.464 80.929  1.00 86.25 ? 377 ALA A O   1 
ATOM   2660 C  CB  . ALA A 1 389 ? 95.175  103.285 83.590  1.00 86.25 ? 377 ALA A CB  1 
ATOM   2661 N  N   . VAL A 1 390 ? 95.223  100.294 82.790  1.00 89.57 ? 378 VAL A N   1 
ATOM   2662 C  CA  . VAL A 1 390 ? 95.859  99.218  82.059  1.00 89.57 ? 378 VAL A CA  1 
ATOM   2663 C  C   . VAL A 1 390 ? 94.861  98.552  81.127  1.00 89.57 ? 378 VAL A C   1 
ATOM   2664 O  O   . VAL A 1 390 ? 95.173  98.290  79.970  1.00 89.57 ? 378 VAL A O   1 
ATOM   2665 C  CB  . VAL A 1 390 ? 96.450  98.193  83.034  1.00 89.57 ? 378 VAL A CB  1 
ATOM   2666 C  CG1 . VAL A 1 390 ? 96.646  96.853  82.361  1.00 89.57 ? 378 VAL A CG1 1 
ATOM   2667 C  CG2 . VAL A 1 390 ? 97.747  98.714  83.631  1.00 89.57 ? 378 VAL A CG2 1 
ATOM   2668 N  N   . THR A 1 391 ? 93.645  98.328  81.605  1.00 90.59 ? 379 THR A N   1 
ATOM   2669 C  CA  . THR A 1 391 ? 92.622  97.708  80.778  1.00 90.59 ? 379 THR A CA  1 
ATOM   2670 C  C   . THR A 1 391 ? 92.452  98.502  79.494  1.00 90.59 ? 379 THR A C   1 
ATOM   2671 O  O   . THR A 1 391 ? 92.200  97.931  78.434  1.00 90.59 ? 379 THR A O   1 
ATOM   2672 C  CB  . THR A 1 391 ? 91.277  97.644  81.521  1.00 90.59 ? 379 THR A CB  1 
ATOM   2673 O  OG1 . THR A 1 391 ? 91.490  97.173  82.856  1.00 90.59 ? 379 THR A OG1 1 
ATOM   2674 C  CG2 . THR A 1 391 ? 90.307  96.716  80.811  1.00 90.59 ? 379 THR A CG2 1 
ATOM   2675 N  N   . MET A 1 392 ? 92.610  99.818  79.578  1.00 85.65 ? 380 MET A N   1 
ATOM   2676 C  CA  . MET A 1 392 ? 92.432  100.680 78.408  1.00 85.65 ? 380 MET A CA  1 
ATOM   2677 C  C   . MET A 1 392 ? 93.654  100.733 77.501  1.00 85.65 ? 380 MET A C   1 
ATOM   2678 O  O   . MET A 1 392 ? 93.529  100.991 76.306  1.00 85.65 ? 380 MET A O   1 
ATOM   2679 C  CB  . MET A 1 392 ? 92.052  102.096 78.841  1.00 85.65 ? 380 MET A CB  1 
ATOM   2680 C  CG  . MET A 1 392 ? 90.794  102.164 79.686  1.00 85.65 ? 380 MET A CG  1 
ATOM   2681 S  SD  . MET A 1 392 ? 89.375  101.410 78.869  1.00 85.65 ? 380 MET A SD  1 
ATOM   2682 C  CE  . MET A 1 392 ? 89.282  102.386 77.369  1.00 85.65 ? 380 MET A CE  1 
ATOM   2683 N  N   . MET A 1 393 ? 94.833  100.490 78.061  1.00 85.18 ? 381 MET A N   1 
ATOM   2684 C  CA  . MET A 1 393 ? 96.059  100.532 77.272  1.00 85.18 ? 381 MET A CA  1 
ATOM   2685 C  C   . MET A 1 393 ? 96.112  99.423  76.233  1.00 85.18 ? 381 MET A C   1 
ATOM   2686 O  O   . MET A 1 393 ? 95.600  98.331  76.467  1.00 85.18 ? 381 MET A O   1 
ATOM   2687 C  CB  . MET A 1 393 ? 97.287  100.440 78.174  1.00 85.18 ? 381 MET A CB  1 
ATOM   2688 C  CG  . MET A 1 393 ? 97.530  101.665 79.028  1.00 85.18 ? 381 MET A CG  1 
ATOM   2689 S  SD  . MET A 1 393 ? 99.289  101.866 79.336  1.00 85.18 ? 381 MET A SD  1 
ATOM   2690 C  CE  . MET A 1 393 ? 99.886  101.896 77.649  1.00 85.18 ? 381 MET A CE  1 
ATOM   2691 N  N   . PRO A 1 394 ? 96.731  99.696  75.073  1.00 86.97 ? 382 PRO A N   1 
ATOM   2692 C  CA  . PRO A 1 394 ? 96.890  98.652  74.053  1.00 86.97 ? 382 PRO A CA  1 
ATOM   2693 C  C   . PRO A 1 394 ? 97.780  97.556  74.601  1.00 86.97 ? 382 PRO A C   1 
ATOM   2694 O  O   . PRO A 1 394 ? 98.679  97.894  75.365  1.00 86.97 ? 382 PRO A O   1 
ATOM   2695 C  CB  . PRO A 1 394 ? 97.609  99.380  72.918  1.00 86.97 ? 382 PRO A CB  1 
ATOM   2696 C  CG  . PRO A 1 394 ? 97.279  100.820 73.114  1.00 86.97 ? 382 PRO A CG  1 
ATOM   2697 C  CD  . PRO A 1 394 ? 97.188  101.013 74.597  1.00 86.97 ? 382 PRO A CD  1 
ATOM   2698 N  N   . LEU A 1 395 ? 97.557  96.294  74.232  1.00 91.16 ? 383 LEU A N   1 
ATOM   2699 C  CA  . LEU A 1 395 ? 98.322  95.190  74.826  1.00 91.16 ? 383 LEU A CA  1 
ATOM   2700 C  C   . LEU A 1 395 ? 98.241  95.283  76.338  1.00 91.16 ? 383 LEU A C   1 
ATOM   2701 O  O   . LEU A 1 395 ? 99.269  95.342  77.008  1.00 91.16 ? 383 LEU A O   1 
ATOM   2702 C  CB  . LEU A 1 395 ? 99.780  95.183  74.359  1.00 91.16 ? 383 LEU A CB  1 
ATOM   2703 C  CG  . LEU A 1 395 ? 100.022 94.975  72.866  1.00 91.16 ? 383 LEU A CG  1 
ATOM   2704 C  CD1 . LEU A 1 395 ? 101.504 95.104  72.553  1.00 91.16 ? 383 LEU A CD1 1 
ATOM   2705 C  CD2 . LEU A 1 395 ? 99.491  93.620  72.427  1.00 91.16 ? 383 LEU A CD2 1 
ATOM   2706 N  N   . PRO A 1 396 ? 97.017  95.273  76.894  1.00 92.57 ? 384 PRO A N   1 
ATOM   2707 C  CA  . PRO A 1 396 ? 96.902  95.513  78.338  1.00 92.57 ? 384 PRO A CA  1 
ATOM   2708 C  C   . PRO A 1 396 ? 97.656  94.531  79.221  1.00 92.57 ? 384 PRO A C   1 
ATOM   2709 O  O   . PRO A 1 396 ? 98.246  94.961  80.206  1.00 92.57 ? 384 PRO A O   1 
ATOM   2710 C  CB  . PRO A 1 396 ? 95.399  95.379  78.590  1.00 92.57 ? 384 PRO A CB  1 
ATOM   2711 C  CG  . PRO A 1 396 ? 94.893  94.512  77.495  1.00 92.57 ? 384 PRO A CG  1 
ATOM   2712 C  CD  . PRO A 1 396 ? 95.748  94.810  76.302  1.00 92.57 ? 384 PRO A CD  1 
ATOM   2713 N  N   . THR A 1 397 ? 97.642  93.249  78.887  1.00 95.60 ? 385 THR A N   1 
ATOM   2714 C  CA  . THR A 1 397 ? 98.374  92.272  79.670  1.00 95.60 ? 385 THR A CA  1 
ATOM   2715 C  C   . THR A 1 397 ? 99.833  92.684  79.832  1.00 95.60 ? 385 THR A C   1 
ATOM   2716 O  O   . THR A 1 397 ? 100.362 92.646  80.939  1.00 95.60 ? 385 THR A O   1 
ATOM   2717 C  CB  . THR A 1 397 ? 98.281  90.870  79.042  1.00 95.60 ? 385 THR A CB  1 
ATOM   2718 O  OG1 . THR A 1 397 ? 96.905  90.529  78.837  1.00 95.60 ? 385 THR A OG1 1 
ATOM   2719 C  CG2 . THR A 1 397 ? 98.922  89.830  79.947  1.00 95.60 ? 385 THR A CG2 1 
ATOM   2720 N  N   . PHE A 1 398 ? 100.478 93.110  78.750  1.00 93.47 ? 386 PHE A N   1 
ATOM   2721 C  CA  . PHE A 1 398 ? 101.892 93.448  78.815  1.00 93.47 ? 386 PHE A CA  1 
ATOM   2722 C  C   . PHE A 1 398 ? 102.101 94.608  79.757  1.00 93.47 ? 386 PHE A C   1 
ATOM   2723 O  O   . PHE A 1 398 ? 103.010 94.591  80.584  1.00 93.47 ? 386 PHE A O   1 
ATOM   2724 C  CB  . PHE A 1 398 ? 102.388 93.823  77.420  1.00 93.47 ? 386 PHE A CB  1 
ATOM   2725 C  CG  . PHE A 1 398 ? 103.762 94.426  77.401  1.00 93.47 ? 386 PHE A CG  1 
ATOM   2726 C  CD1 . PHE A 1 398 ? 104.865 93.683  77.784  1.00 93.47 ? 386 PHE A CD1 1 
ATOM   2727 C  CD2 . PHE A 1 398 ? 103.951 95.730  76.980  1.00 93.47 ? 386 PHE A CD2 1 
ATOM   2728 C  CE1 . PHE A 1 398 ? 106.130 94.235  77.763  1.00 93.47 ? 386 PHE A CE1 1 
ATOM   2729 C  CE2 . PHE A 1 398 ? 105.213 96.288  76.954  1.00 93.47 ? 386 PHE A CE2 1 
ATOM   2730 C  CZ  . PHE A 1 398 ? 106.305 95.539  77.344  1.00 93.47 ? 386 PHE A CZ  1 
ATOM   2731 N  N   . TRP A 1 399 ? 101.251 95.614  79.645  1.00 91.31 ? 387 TRP A N   1 
ATOM   2732 C  CA  . TRP A 1 399 ? 101.351 96.776  80.518  1.00 91.31 ? 387 TRP A CA  1 
ATOM   2733 C  C   . TRP A 1 399 ? 101.047 96.502  81.985  1.00 91.31 ? 387 TRP A C   1 
ATOM   2734 O  O   . TRP A 1 399 ? 101.638 97.117  82.860  1.00 91.31 ? 387 TRP A O   1 
ATOM   2735 C  CB  . TRP A 1 399 ? 100.600 97.968  79.938  1.00 91.31 ? 387 TRP A CB  1 
ATOM   2736 C  CG  . TRP A 1 399 ? 101.248 98.389  78.665  1.00 91.31 ? 387 TRP A CG  1 
ATOM   2737 C  CD1 . TRP A 1 399 ? 100.901 98.004  77.413  1.00 91.31 ? 387 TRP A CD1 1 
ATOM   2738 C  CD2 . TRP A 1 399 ? 102.404 99.221  78.521  1.00 91.31 ? 387 TRP A CD2 1 
ATOM   2739 N  NE1 . TRP A 1 399 ? 101.739 98.569  76.487  1.00 91.31 ? 387 TRP A NE1 1 
ATOM   2740 C  CE2 . TRP A 1 399 ? 102.676 99.320  77.144  1.00 91.31 ? 387 TRP A CE2 1 
ATOM   2741 C  CE3 . TRP A 1 399 ? 103.224 99.904  79.420  1.00 91.31 ? 387 TRP A CE3 1 
ATOM   2742 C  CZ2 . TRP A 1 399 ? 103.732 100.074 76.646  1.00 91.31 ? 387 TRP A CZ2 1 
ATOM   2743 C  CZ3 . TRP A 1 399 ? 104.273 100.649 78.923  1.00 91.31 ? 387 TRP A CZ3 1 
ATOM   2744 C  CH2 . TRP A 1 399 ? 104.517 100.730 77.550  1.00 91.31 ? 387 TRP A CH2 1 
ATOM   2745 N  N   . SER A 1 400 ? 100.107 95.603  82.253  1.00 94.77 ? 388 SER A N   1 
ATOM   2746 C  CA  . SER A 1 400 ? 99.769  95.278  83.629  1.00 94.77 ? 388 SER A CA  1 
ATOM   2747 C  C   . SER A 1 400 ? 100.961 94.707  84.353  1.00 94.77 ? 388 SER A C   1 
ATOM   2748 O  O   . SER A 1 400 ? 101.238 95.075  85.488  1.00 94.77 ? 388 SER A O   1 
ATOM   2749 C  CB  . SER A 1 400 ? 98.653  94.249  83.677  1.00 94.77 ? 388 SER A CB  1 
ATOM   2750 O  OG  . SER A 1 400 ? 98.355  93.920  85.016  1.00 94.77 ? 388 SER A OG  1 
ATOM   2751 N  N   . ILE A 1 401 ? 101.690 93.826  83.686  1.00 95.54 ? 389 ILE A N   1 
ATOM   2752 C  CA  . ILE A 1 401 ? 102.861 93.245  84.302  1.00 95.54 ? 389 ILE A CA  1 
ATOM   2753 C  C   . ILE A 1 401 ? 103.836 94.363  84.595  1.00 95.54 ? 389 ILE A C   1 
ATOM   2754 O  O   . ILE A 1 401 ? 104.364 94.450  85.694  1.00 95.54 ? 389 ILE A O   1 
ATOM   2755 C  CB  . ILE A 1 401 ? 103.539 92.259  83.343  1.00 95.54 ? 389 ILE A CB  1 
ATOM   2756 C  CG1 . ILE A 1 401 ? 102.535 91.212  82.862  1.00 95.54 ? 389 ILE A CG1 1 
ATOM   2757 C  CG2 . ILE A 1 401 ? 104.746 91.608  83.999  1.00 95.54 ? 389 ILE A CG2 1 
ATOM   2758 C  CD1 . ILE A 1 401 ? 102.977 90.477  81.616  1.00 95.54 ? 389 ILE A CD1 1 
ATOM   2759 N  N   . LEU A 1 402 ? 104.038 95.257  83.639  1.00 92.85 ? 390 LEU A N   1 
ATOM   2760 C  CA  . LEU A 1 402 ? 104.969 96.356  83.840  1.00 92.85 ? 390 LEU A CA  1 
ATOM   2761 C  C   . LEU A 1 402 ? 104.592 97.210  85.045  1.00 92.85 ? 390 LEU A C   1 
ATOM   2762 O  O   . LEU A 1 402 ? 105.446 97.530  85.868  1.00 92.85 ? 390 LEU A O   1 
ATOM   2763 C  CB  . LEU A 1 402 ? 105.076 97.219  82.587  1.00 92.85 ? 390 LEU A CB  1 
ATOM   2764 C  CG  . LEU A 1 402 ? 105.698 96.568  81.355  1.00 92.85 ? 390 LEU A CG  1 
ATOM   2765 C  CD1 . LEU A 1 402 ? 106.075 97.652  80.363  1.00 92.85 ? 390 LEU A CD1 1 
ATOM   2766 C  CD2 . LEU A 1 402 ? 106.929 95.764  81.741  1.00 92.85 ? 390 LEU A CD2 1 
ATOM   2767 N  N   . PHE A 1 403 ? 103.322 97.581  85.159  1.00 92.02 ? 391 PHE A N   1 
ATOM   2768 C  CA  . PHE A 1 403 ? 102.914 98.462  86.248  1.00 92.02 ? 391 PHE A CA  1 
ATOM   2769 C  C   . PHE A 1 403 ? 103.105 97.866  87.636  1.00 92.02 ? 391 PHE A C   1 
ATOM   2770 O  O   . PHE A 1 403 ? 103.599 98.530  88.540  1.00 92.02 ? 391 PHE A O   1 
ATOM   2771 C  CB  . PHE A 1 403 ? 101.454 98.881  86.069  1.00 92.02 ? 391 PHE A CB  1 
ATOM   2772 C  CG  . PHE A 1 403 ? 100.861 99.516  87.288  1.00 92.02 ? 391 PHE A CG  1 
ATOM   2773 C  CD1 . PHE A 1 403 ? 101.308 100.748 87.725  1.00 92.02 ? 391 PHE A CD1 1 
ATOM   2774 C  CD2 . PHE A 1 403 ? 99.866  98.877  88.000  1.00 92.02 ? 391 PHE A CD2 1 
ATOM   2775 C  CE1 . PHE A 1 403 ? 100.776 101.329 88.854  1.00 92.02 ? 391 PHE A CE1 1 
ATOM   2776 C  CE2 . PHE A 1 403 ? 99.328  99.454  89.129  1.00 92.02 ? 391 PHE A CE2 1 
ATOM   2777 C  CZ  . PHE A 1 403 ? 99.787  100.679 89.559  1.00 92.02 ? 391 PHE A CZ  1 
ATOM   2778 N  N   . PHE A 1 404 ? 102.714 96.614  87.814  1.00 95.33 ? 392 PHE A N   1 
ATOM   2779 C  CA  . PHE A 1 404 ? 102.889 95.958  89.107  1.00 95.33 ? 392 PHE A CA  1 
ATOM   2780 C  C   . PHE A 1 404 ? 104.348 95.744  89.450  1.00 95.33 ? 392 PHE A C   1 
ATOM   2781 O  O   . PHE A 1 404 ? 104.728 95.830  90.611  1.00 95.33 ? 392 PHE A O   1 
ATOM   2782 C  CB  . PHE A 1 404 ? 101.994 94.732  89.256  1.00 95.33 ? 392 PHE A CB  1 
ATOM   2783 C  CG  . PHE A 1 404 ? 100.536 95.078  89.233  1.00 95.33 ? 392 PHE A CG  1 
ATOM   2784 C  CD1 . PHE A 1 404 ? 99.981  95.826  90.255  1.00 95.33 ? 392 PHE A CD1 1 
ATOM   2785 C  CD2 . PHE A 1 404 ? 99.733  94.701  88.175  1.00 95.33 ? 392 PHE A CD2 1 
ATOM   2786 C  CE1 . PHE A 1 404 ? 98.646  96.173  90.233  1.00 95.33 ? 392 PHE A CE1 1 
ATOM   2787 C  CE2 . PHE A 1 404 ? 98.398  95.045  88.144  1.00 95.33 ? 392 PHE A CE2 1 
ATOM   2788 C  CZ  . PHE A 1 404 ? 97.854  95.785  89.173  1.00 95.33 ? 392 PHE A CZ  1 
ATOM   2789 N  N   . ILE A 1 405 ? 105.169 95.457  88.448  1.00 95.36 ? 393 ILE A N   1 
ATOM   2790 C  CA  . ILE A 1 405 ? 106.598 95.329  88.689  1.00 95.36 ? 393 ILE A CA  1 
ATOM   2791 C  C   . ILE A 1 405 ? 107.099 96.671  89.200  1.00 95.36 ? 393 ILE A C   1 
ATOM   2792 O  O   . ILE A 1 405 ? 107.909 96.723  90.115  1.00 95.36 ? 393 ILE A O   1 
ATOM   2793 C  CB  . ILE A 1 405 ? 107.359 94.930  87.412  1.00 95.36 ? 393 ILE A CB  1 
ATOM   2794 C  CG1 . ILE A 1 405 ? 107.121 93.459  87.086  1.00 95.36 ? 393 ILE A CG1 1 
ATOM   2795 C  CG2 . ILE A 1 405 ? 108.854 95.156  87.560  1.00 95.36 ? 393 ILE A CG2 1 
ATOM   2796 C  CD1 . ILE A 1 405 ? 107.845 92.997  85.842  1.00 95.36 ? 393 ILE A CD1 1 
ATOM   2797 N  N   . MET A 1 406 ? 106.585 97.761  88.635  1.00 93.99 ? 394 MET A N   1 
ATOM   2798 C  CA  . MET A 1 406 ? 106.972 99.095  89.089  1.00 93.99 ? 394 MET A CA  1 
ATOM   2799 C  C   . MET A 1 406 ? 106.651 99.258  90.562  1.00 93.99 ? 394 MET A C   1 
ATOM   2800 O  O   . MET A 1 406 ? 107.487 99.714  91.332  1.00 93.99 ? 394 MET A O   1 
ATOM   2801 C  CB  . MET A 1 406 ? 106.254 100.178 88.283  1.00 93.99 ? 394 MET A CB  1 
ATOM   2802 C  CG  . MET A 1 406 ? 106.459 101.585 88.809  1.00 93.99 ? 394 MET A CG  1 
ATOM   2803 S  SD  . MET A 1 406 ? 105.284 102.777 88.146  1.00 93.99 ? 394 MET A SD  1 
ATOM   2804 C  CE  . MET A 1 406 ? 104.083 102.831 89.468  1.00 93.99 ? 394 MET A CE  1 
ATOM   2805 N  N   . LEU A 1 407 ? 105.447 98.866  90.964  1.00 93.90 ? 395 LEU A N   1 
ATOM   2806 C  CA  . LEU A 1 407 ? 105.048 99.036  92.353  1.00 93.90 ? 395 LEU A CA  1 
ATOM   2807 C  C   . LEU A 1 407 ? 105.956 98.233  93.246  1.00 93.90 ? 395 LEU A C   1 
ATOM   2808 O  O   . LEU A 1 407 ? 106.385 98.711  94.289  1.00 93.90 ? 395 LEU A O   1 
ATOM   2809 C  CB  . LEU A 1 407 ? 103.616 98.559  92.572  1.00 93.90 ? 395 LEU A CB  1 
ATOM   2810 C  CG  . LEU A 1 407 ? 102.474 99.332  91.922  1.00 93.90 ? 395 LEU A CG  1 
ATOM   2811 C  CD1 . LEU A 1 407 ? 101.155 98.744  92.391  1.00 93.90 ? 395 LEU A CD1 1 
ATOM   2812 C  CD2 . LEU A 1 407 ? 102.559 100.799 92.300  1.00 93.90 ? 395 LEU A CD2 1 
ATOM   2813 N  N   . LEU A 1 408 ? 106.262 97.011  92.832  1.00 96.25 ? 396 LEU A N   1 
ATOM   2814 C  CA  . LEU A 1 408 ? 107.128 96.166  93.629  1.00 96.25 ? 396 LEU A CA  1 
ATOM   2815 C  C   . LEU A 1 408 ? 108.519 96.768  93.753  1.00 96.25 ? 396 LEU A C   1 
ATOM   2816 O  O   . LEU A 1 408 ? 109.073 96.811  94.837  1.00 96.25 ? 396 LEU A O   1 
ATOM   2817 C  CB  . LEU A 1 408 ? 107.202 94.758  93.046  1.00 96.25 ? 396 LEU A CB  1 
ATOM   2818 C  CG  . LEU A 1 408 ? 105.923 93.935  93.175  1.00 96.25 ? 396 LEU A CG  1 
ATOM   2819 C  CD1 . LEU A 1 408 ? 106.041 92.632  92.403  1.00 96.25 ? 396 LEU A CD1 1 
ATOM   2820 C  CD2 . LEU A 1 408 ? 105.626 93.672  94.639  1.00 96.25 ? 396 LEU A CD2 1 
ATOM   2821 N  N   . LEU A 1 409 ? 109.066 97.275  92.657  1.00 96.46 ? 397 LEU A N   1 
ATOM   2822 C  CA  . LEU A 1 409 ? 110.379 97.884  92.716  1.00 96.46 ? 397 LEU A CA  1 
ATOM   2823 C  C   . LEU A 1 409 ? 110.362 99.105  93.609  1.00 96.46 ? 397 LEU A C   1 
ATOM   2824 O  O   . LEU A 1 409 ? 111.241 99.274  94.441  1.00 96.46 ? 397 LEU A O   1 
ATOM   2825 C  CB  . LEU A 1 409 ? 110.848 98.289  91.320  1.00 96.46 ? 397 LEU A CB  1 
ATOM   2826 C  CG  . LEU A 1 409 ? 111.189 97.181  90.327  1.00 96.46 ? 397 LEU A CG  1 
ATOM   2827 C  CD1 . LEU A 1 409 ? 111.556 97.786  88.981  1.00 96.46 ? 397 LEU A CD1 1 
ATOM   2828 C  CD2 . LEU A 1 409 ? 112.322 96.321  90.861  1.00 96.46 ? 397 LEU A CD2 1 
ATOM   2829 N  N   . LEU A 1 410 ? 109.347 99.947  93.461  1.00 95.24 ? 398 LEU A N   1 
ATOM   2830 C  CA  . LEU A 1 410 ? 109.270 101.171 94.251  1.00 95.24 ? 398 LEU A CA  1 
ATOM   2831 C  C   . LEU A 1 410 ? 109.113 100.900 95.725  1.00 95.24 ? 398 LEU A C   1 
ATOM   2832 O  O   . LEU A 1 410 ? 109.750 101.548 96.551  1.00 95.24 ? 398 LEU A O   1 
ATOM   2833 C  CB  . LEU A 1 410 ? 108.119 102.047 93.773  1.00 95.24 ? 398 LEU A CB  1 
ATOM   2834 C  CG  . LEU A 1 410 ? 108.483 102.977 92.626  1.00 95.24 ? 398 LEU A CG  1 
ATOM   2835 C  CD1 . LEU A 1 410 ? 107.318 103.895 92.301  1.00 95.24 ? 398 LEU A CD1 1 
ATOM   2836 C  CD2 . LEU A 1 410 ? 109.714 103.782 93.007  1.00 95.24 ? 398 LEU A CD2 1 
ATOM   2837 N  N   . GLY A 1 411 ? 108.276 99.933  96.063  1.00 95.96 ? 399 GLY A N   1 
ATOM   2838 C  CA  . GLY A 1 411 ? 108.020 99.655  97.457  1.00 95.96 ? 399 GLY A CA  1 
ATOM   2839 C  C   . GLY A 1 411 ? 109.154 98.892  98.090  1.00 95.96 ? 399 GLY A C   1 
ATOM   2840 O  O   . GLY A 1 411 ? 109.553 99.196  99.205  1.00 95.96 ? 399 GLY A O   1 
ATOM   2841 N  N   . LEU A 1 412 ? 109.670 97.895  97.385  1.00 96.78 ? 400 LEU A N   1 
ATOM   2842 C  CA  . LEU A 1 412 ? 110.754 97.091  97.926  1.00 96.78 ? 400 LEU A CA  1 
ATOM   2843 C  C   . LEU A 1 412 ? 111.989 97.921  98.230  1.00 96.78 ? 400 LEU A C   1 
ATOM   2844 O  O   . LEU A 1 412 ? 112.625 97.712  99.246  1.00 96.78 ? 400 LEU A O   1 
ATOM   2845 C  CB  . LEU A 1 412 ? 111.098 95.912  97.023  1.00 96.78 ? 400 LEU A CB  1 
ATOM   2846 C  CG  . LEU A 1 412 ? 110.242 94.676  97.277  1.00 96.78 ? 400 LEU A CG  1 
ATOM   2847 C  CD1 . LEU A 1 412 ? 110.490 93.618  96.216  1.00 96.78 ? 400 LEU A CD1 1 
ATOM   2848 C  CD2 . LEU A 1 412 ? 110.520 94.131  98.670  1.00 96.78 ? 400 LEU A CD2 1 
ATOM   2849 N  N   . ASP A 1 413 ? 112.318 98.874  97.369  1.00 96.09 ? 401 ASP A N   1 
ATOM   2850 C  CA  . ASP A 1 413 ? 113.475 99.719  97.615  1.00 96.09 ? 401 ASP A CA  1 
ATOM   2851 C  C   . ASP A 1 413 ? 113.272 100.507 98.896  1.00 96.09 ? 401 ASP A C   1 
ATOM   2852 O  O   . ASP A 1 413 ? 114.175 100.593 99.724  1.00 96.09 ? 401 ASP A O   1 
ATOM   2853 C  CB  . ASP A 1 413 ? 113.707 100.668 96.439  1.00 96.09 ? 401 ASP A CB  1 
ATOM   2854 C  CG  . ASP A 1 413 ? 114.137 99.942  95.177  1.00 96.09 ? 401 ASP A CG  1 
ATOM   2855 O  OD1 . ASP A 1 413 ? 114.510 98.751  95.264  1.00 96.09 ? 401 ASP A OD1 1 
ATOM   2856 O  OD2 . ASP A 1 413 ? 114.106 100.567 94.096  1.00 96.09 ? 401 ASP A OD2 1 
ATOM   2857 N  N   . SER A 1 414 ? 112.078 101.053 99.085  1.00 95.69 ? 402 SER A N   1 
ATOM   2858 C  CA  . SER A 1 414 ? 111.781 101.773 100.314 1.00 95.69 ? 402 SER A CA  1 
ATOM   2859 C  C   . SER A 1 414 ? 111.843 100.832 101.498 1.00 95.69 ? 402 SER A C   1 
ATOM   2860 O  O   . SER A 1 414 ? 112.380 101.182 102.545 1.00 95.69 ? 402 SER A O   1 
ATOM   2861 C  CB  . SER A 1 414 ? 110.403 102.414 100.226 1.00 95.69 ? 402 SER A CB  1 
ATOM   2862 O  OG  . SER A 1 414 ? 110.341 103.321 99.140  1.00 95.69 ? 402 SER A OG  1 
ATOM   2863 N  N   . GLN A 1 415 ? 111.275 99.640  101.348 1.00 96.88 ? 403 GLN A N   1 
ATOM   2864 C  CA  . GLN A 1 415 ? 111.245 98.674  102.443 1.00 96.88 ? 403 GLN A CA  1 
ATOM   2865 C  C   . GLN A 1 415 ? 112.646 98.282  102.856 1.00 96.88 ? 403 GLN A C   1 
ATOM   2866 O  O   . GLN A 1 415 ? 112.932 98.187  104.037 1.00 96.88 ? 403 GLN A O   1 
ATOM   2867 C  CB  . GLN A 1 415 ? 110.442 97.431  102.052 1.00 96.88 ? 403 GLN A CB  1 
ATOM   2868 C  CG  . GLN A 1 415 ? 110.340 96.370  103.135 1.00 96.88 ? 403 GLN A CG  1 
ATOM   2869 C  CD  . GLN A 1 415 ? 109.186 96.606  104.088 1.00 96.88 ? 403 GLN A CD  1 
ATOM   2870 O  OE1 . GLN A 1 415 ? 108.265 97.363  103.790 1.00 96.88 ? 403 GLN A OE1 1 
ATOM   2871 N  NE2 . GLN A 1 415 ? 109.220 95.941  105.234 1.00 96.88 ? 403 GLN A NE2 1 
ATOM   2872 N  N   . PHE A 1 416 ? 113.535 98.076  101.893 1.00 95.64 ? 404 PHE A N   1 
ATOM   2873 C  CA  . PHE A 1 416 ? 114.872 97.627  102.238 1.00 95.64 ? 404 PHE A CA  1 
ATOM   2874 C  C   . PHE A 1 416 ? 115.523 98.682  103.104 1.00 95.64 ? 404 PHE A C   1 
ATOM   2875 O  O   . PHE A 1 416 ? 116.145 98.358  104.103 1.00 95.64 ? 404 PHE A O   1 
ATOM   2876 C  CB  . PHE A 1 416 ? 115.751 97.436  101.002 1.00 95.64 ? 404 PHE A CB  1 
ATOM   2877 C  CG  . PHE A 1 416 ? 115.283 96.360  100.071 1.00 95.64 ? 404 PHE A CG  1 
ATOM   2878 C  CD1 . PHE A 1 416 ? 114.661 95.224  100.552 1.00 95.64 ? 404 PHE A CD1 1 
ATOM   2879 C  CD2 . PHE A 1 416 ? 115.490 96.481  98.707  1.00 95.64 ? 404 PHE A CD2 1 
ATOM   2880 C  CE1 . PHE A 1 416 ? 114.236 94.238  99.686  1.00 95.64 ? 404 PHE A CE1 1 
ATOM   2881 C  CE2 . PHE A 1 416 ? 115.066 95.498  97.837  1.00 95.64 ? 404 PHE A CE2 1 
ATOM   2882 C  CZ  . PHE A 1 416 ? 114.439 94.372  98.328  1.00 95.64 ? 404 PHE A CZ  1 
ATOM   2883 N  N   . VAL A 1 417 ? 115.369 99.949  102.733 1.00 96.10 ? 405 VAL A N   1 
ATOM   2884 C  CA  . VAL A 1 417 ? 115.986 101.025 103.497 1.00 96.10 ? 405 VAL A CA  1 
ATOM   2885 C  C   . VAL A 1 417 ? 115.417 101.096 104.910 1.00 96.10 ? 405 VAL A C   1 
ATOM   2886 O  O   . VAL A 1 417 ? 116.166 101.206 105.878 1.00 96.10 ? 405 VAL A O   1 
ATOM   2887 C  CB  . VAL A 1 417 ? 115.807 102.383 102.787 1.00 96.10 ? 405 VAL A CB  1 
ATOM   2888 C  CG1 . VAL A 1 417 ? 116.342 103.522 103.640 1.00 96.10 ? 405 VAL A CG1 1 
ATOM   2889 C  CG2 . VAL A 1 417 ? 116.496 102.366 101.432 1.00 96.10 ? 405 VAL A CG2 1 
ATOM   2890 N  N   . GLU A 1 418 ? 114.098 100.992 105.039 1.00 96.84 ? 406 GLU A N   1 
ATOM   2891 C  CA  . GLU A 1 418 ? 113.476 101.025 106.357 1.00 96.84 ? 406 GLU A CA  1 
ATOM   2892 C  C   . GLU A 1 418 ? 113.889 99.837  107.204 1.00 96.84 ? 406 GLU A C   1 
ATOM   2893 O  O   . GLU A 1 418 ? 114.197 99.992  108.382 1.00 96.84 ? 406 GLU A O   1 
ATOM   2894 C  CB  . GLU A 1 418 ? 111.955 101.062 106.231 1.00 96.84 ? 406 GLU A CB  1 
ATOM   2895 C  CG  . GLU A 1 418 ? 111.409 102.262 105.478 1.00 96.84 ? 406 GLU A CG  1 
ATOM   2896 C  CD  . GLU A 1 418 ? 111.508 103.552 106.266 1.00 96.84 ? 406 GLU A CD  1 
ATOM   2897 O  OE1 . GLU A 1 418 ? 111.479 103.501 107.514 1.00 96.84 ? 406 GLU A OE1 1 
ATOM   2898 O  OE2 . GLU A 1 418 ? 111.598 104.623 105.632 1.00 96.84 ? 406 GLU A OE2 1 
ATOM   2899 N  N   . VAL A 1 419 ? 113.903 98.649  106.608 1.00 97.30 ? 407 VAL A N   1 
ATOM   2900 C  CA  . VAL A 1 419 ? 114.315 97.460  107.337 1.00 97.30 ? 407 VAL A CA  1 
ATOM   2901 C  C   . VAL A 1 419 ? 115.772 97.579  107.729 1.00 97.30 ? 407 VAL A C   1 
ATOM   2902 O  O   . VAL A 1 419 ? 116.130 97.318  108.868 1.00 97.30 ? 407 VAL A O   1 
ATOM   2903 C  CB  . VAL A 1 419 ? 114.073 96.174  106.527 1.00 97.30 ? 407 VAL A CB  1 
ATOM   2904 C  CG1 . VAL A 1 419 ? 114.797 94.987  107.146 1.00 97.30 ? 407 VAL A CG1 1 
ATOM   2905 C  CG2 . VAL A 1 419 ? 112.584 95.889  106.438 1.00 97.30 ? 407 VAL A CG2 1 
ATOM   2906 N  N   . GLU A 1 420 ? 116.606 98.042  106.807 1.00 96.10 ? 408 GLU A N   1 
ATOM   2907 C  CA  . GLU A 1 420 ? 118.024 98.159  107.097 1.00 96.10 ? 408 GLU A CA  1 
ATOM   2908 C  C   . GLU A 1 420 ? 118.223 99.157  108.212 1.00 96.10 ? 408 GLU A C   1 
ATOM   2909 O  O   . GLU A 1 420 ? 119.022 98.933  109.114 1.00 96.10 ? 408 GLU A O   1 
ATOM   2910 C  CB  . GLU A 1 420 ? 118.811 98.580  105.859 1.00 96.10 ? 408 GLU A CB  1 
ATOM   2911 C  CG  . GLU A 1 420 ? 120.319 98.536  106.044 1.00 96.10 ? 408 GLU A CG  1 
ATOM   2912 C  CD  . GLU A 1 420 ? 120.833 97.137  106.329 1.00 96.10 ? 408 GLU A CD  1 
ATOM   2913 O  OE1 . GLU A 1 420 ? 121.664 96.982  107.248 1.00 96.10 ? 408 GLU A OE1 1 
ATOM   2914 O  OE2 . GLU A 1 420 ? 120.404 96.188  105.640 1.00 96.10 ? 408 GLU A OE2 1 
ATOM   2915 N  N   . GLY A 1 421 ? 117.477 100.254 108.170 1.00 96.68 ? 409 GLY A N   1 
ATOM   2916 C  CA  . GLY A 1 421 ? 117.593 101.262 109.202 1.00 96.68 ? 409 GLY A CA  1 
ATOM   2917 C  C   . GLY A 1 421 ? 117.199 100.712 110.553 1.00 96.68 ? 409 GLY A C   1 
ATOM   2918 O  O   . GLY A 1 421 ? 117.872 100.965 111.550 1.00 96.68 ? 409 GLY A O   1 
ATOM   2919 N  N   . GLN A 1 422 ? 116.123 99.934  110.591 1.00 97.56 ? 410 GLN A N   1 
ATOM   2920 C  CA  . GLN A 1 422 ? 115.688 99.349  111.844 1.00 97.56 ? 410 GLN A CA  1 
ATOM   2921 C  C   . GLN A 1 422 ? 116.761 98.417  112.368 1.00 97.56 ? 410 GLN A C   1 
ATOM   2922 O  O   . GLN A 1 422 ? 117.120 98.481  113.540 1.00 97.56 ? 410 GLN A O   1 
ATOM   2923 C  CB  . GLN A 1 422 ? 114.392 98.571  111.639 1.00 97.56 ? 410 GLN A CB  1 
ATOM   2924 C  CG  . GLN A 1 422 ? 113.799 97.997  112.912 1.00 97.56 ? 410 GLN A CG  1 
ATOM   2925 C  CD  . GLN A 1 422 ? 112.707 96.986  112.636 1.00 97.56 ? 410 GLN A CD  1 
ATOM   2926 O  OE1 . GLN A 1 422 ? 112.359 96.732  111.485 1.00 97.56 ? 410 GLN A OE1 1 
ATOM   2927 N  NE2 . GLN A 1 422 ? 112.166 96.397  113.694 1.00 97.56 ? 410 GLN A NE2 1 
ATOM   2928 N  N   . ILE A 1 423 ? 117.317 97.584  111.495 1.00 97.23 ? 411 ILE A N   1 
ATOM   2929 C  CA  . ILE A 1 423 ? 118.316 96.626  111.942 1.00 97.23 ? 411 ILE A CA  1 
ATOM   2930 C  C   . ILE A 1 423 ? 119.543 97.350  112.466 1.00 97.23 ? 411 ILE A C   1 
ATOM   2931 O  O   . ILE A 1 423 ? 120.030 97.037  113.545 1.00 97.23 ? 411 ILE A O   1 
ATOM   2932 C  CB  . ILE A 1 423 ? 118.758 95.670  110.814 1.00 97.23 ? 411 ILE A CB  1 
ATOM   2933 C  CG1 . ILE A 1 423 ? 117.563 94.937  110.203 1.00 97.23 ? 411 ILE A CG1 1 
ATOM   2934 C  CG2 . ILE A 1 423 ? 119.776 94.663  111.326 1.00 97.23 ? 411 ILE A CG2 1 
ATOM   2935 C  CD1 . ILE A 1 423 ? 116.733 94.153  111.189 1.00 97.23 ? 411 ILE A CD1 1 
ATOM   2936 N  N   . THR A 1 424 ? 120.013 98.360  111.740 1.00 95.84 ? 412 THR A N   1 
ATOM   2937 C  CA  . THR A 1 424 ? 121.233 99.043  112.154 1.00 95.84 ? 412 THR A CA  1 
ATOM   2938 C  C   . THR A 1 424 ? 121.080 99.756  113.482 1.00 95.84 ? 412 THR A C   1 
ATOM   2939 O  O   . THR A 1 424 ? 121.962 99.683  114.325 1.00 95.84 ? 412 THR A O   1 
ATOM   2940 C  CB  . THR A 1 424 ? 121.734 100.053 111.108 1.00 95.84 ? 412 THR A CB  1 
ATOM   2941 O  OG1 . THR A 1 424 ? 120.668 100.935 110.737 1.00 95.84 ? 412 THR A OG1 1 
ATOM   2942 C  CG2 . THR A 1 424 ? 122.248 99.330  109.875 1.00 95.84 ? 412 THR A CG2 1 
ATOM   2943 N  N   . SER A 1 425 ? 119.955 100.436 113.674 1.00 96.60 ? 413 SER A N   1 
ATOM   2944 C  CA  . SER A 1 425 ? 119.740 101.162 114.915 1.00 96.60 ? 413 SER A CA  1 
ATOM   2945 C  C   . SER A 1 425 ? 119.685 100.190 116.077 1.00 96.60 ? 413 SER A C   1 
ATOM   2946 O  O   . SER A 1 425 ? 120.250 100.448 117.135 1.00 96.60 ? 413 SER A O   1 
ATOM   2947 C  CB  . SER A 1 425 ? 118.460 101.992 114.847 1.00 96.60 ? 413 SER A CB  1 
ATOM   2948 O  OG  . SER A 1 425 ? 117.334 101.176 114.583 1.00 96.60 ? 413 SER A OG  1 
ATOM   2949 N  N   . LEU A 1 426 ? 119.005 99.067  115.884 1.00 96.59 ? 414 LEU A N   1 
ATOM   2950 C  CA  . LEU A 1 426 ? 118.923 98.063  116.933 1.00 96.59 ? 414 LEU A CA  1 
ATOM   2951 C  C   . LEU A 1 426 ? 120.282 97.459  117.251 1.00 96.59 ? 414 LEU A C   1 
ATOM   2952 O  O   . LEU A 1 426 ? 120.595 97.220  118.414 1.00 96.59 ? 414 LEU A O   1 
ATOM   2953 C  CB  . LEU A 1 426 ? 117.875 97.005  116.593 1.00 96.59 ? 414 LEU A CB  1 
ATOM   2954 C  CG  . LEU A 1 426 ? 116.466 97.597  116.687 1.00 96.59 ? 414 LEU A CG  1 
ATOM   2955 C  CD1 . LEU A 1 426 ? 115.395 96.690  116.108 1.00 96.59 ? 414 LEU A CD1 1 
ATOM   2956 C  CD2 . LEU A 1 426 ? 116.137 97.982  118.118 1.00 96.59 ? 414 LEU A CD2 1 
ATOM   2957 N  N   . VAL A 1 427 ? 121.095 97.211  116.232 1.00 94.59 ? 415 VAL A N   1 
ATOM   2958 C  CA  . VAL A 1 427 ? 122.441 96.712  116.480 1.00 94.59 ? 415 VAL A CA  1 
ATOM   2959 C  C   . VAL A 1 427 ? 123.223 97.789  117.214 1.00 94.59 ? 415 VAL A C   1 
ATOM   2960 O  O   . VAL A 1 427 ? 123.918 97.497  118.175 1.00 94.59 ? 415 VAL A O   1 
ATOM   2961 C  CB  . VAL A 1 427 ? 123.169 96.339  115.170 1.00 94.59 ? 415 VAL A CB  1 
ATOM   2962 C  CG1 . VAL A 1 427 ? 124.618 95.961  115.438 1.00 94.59 ? 415 VAL A CG1 1 
ATOM   2963 C  CG2 . VAL A 1 427 ? 122.455 95.197  114.468 1.00 94.59 ? 415 VAL A CG2 1 
ATOM   2964 N  N   . ASP A 1 428 ? 123.088 99.038  116.782 1.00 93.22 ? 416 ASP A N   1 
ATOM   2965 C  CA  . ASP A 1 428 ? 123.824 100.145 117.390 1.00 93.22 ? 416 ASP A CA  1 
ATOM   2966 C  C   . ASP A 1 428 ? 123.725 100.137 118.908 1.00 93.22 ? 416 ASP A C   1 
ATOM   2967 O  O   . ASP A 1 428 ? 124.677 100.498 119.593 1.00 93.22 ? 416 ASP A O   1 
ATOM   2968 C  CB  . ASP A 1 428 ? 123.371 101.495 116.832 1.00 93.22 ? 416 ASP A CB  1 
ATOM   2969 C  CG  . ASP A 1 428 ? 124.077 101.858 115.544 1.00 93.22 ? 416 ASP A CG  1 
ATOM   2970 O  OD1 . ASP A 1 428 ? 124.848 101.019 115.033 1.00 93.22 ? 416 ASP A OD1 1 
ATOM   2971 O  OD2 . ASP A 1 428 ? 123.866 102.981 115.045 1.00 93.22 ? 416 ASP A OD2 1 
ATOM   2972 N  N   . LEU A 1 429 ? 122.570 99.757  119.437 1.00 93.20 ? 417 LEU A N   1 
ATOM   2973 C  CA  . LEU A 1 429 ? 122.386 99.766  120.876 1.00 93.20 ? 417 LEU A CA  1 
ATOM   2974 C  C   . LEU A 1 429 ? 123.369 98.826  121.558 1.00 93.20 ? 417 LEU A C   1 
ATOM   2975 O  O   . LEU A 1 429 ? 123.953 99.180  122.580 1.00 93.20 ? 417 LEU A O   1 
ATOM   2976 C  CB  . LEU A 1 429 ? 120.961 99.339  121.214 1.00 93.20 ? 417 LEU A CB  1 
ATOM   2977 C  CG  . LEU A 1 429 ? 119.843 100.168 120.588 1.00 93.20 ? 417 LEU A CG  1 
ATOM   2978 C  CD1 . LEU A 1 429 ? 118.500 99.470  120.735 1.00 93.20 ? 417 LEU A CD1 1 
ATOM   2979 C  CD2 . LEU A 1 429 ? 119.815 101.549 121.216 1.00 93.20 ? 417 LEU A CD2 1 
ATOM   2980 N  N   . TYR A 1 430 ? 123.562 97.633  121.004 1.00 92.72 ? 418 TYR A N   1 
ATOM   2981 C  CA  . TYR A 1 430 ? 124.531 96.686  121.564 1.00 92.72 ? 418 TYR A CA  1 
ATOM   2982 C  C   . TYR A 1 430 ? 125.399 96.094  120.464 1.00 92.72 ? 418 TYR A C   1 
ATOM   2983 O  O   . TYR A 1 430 ? 125.258 94.920  120.126 1.00 92.72 ? 418 TYR A O   1 
ATOM   2984 C  CB  . TYR A 1 430 ? 123.810 95.577  122.338 1.00 92.72 ? 418 TYR A CB  1 
ATOM   2985 C  CG  . TYR A 1 430 ? 122.351 95.414  121.967 1.00 92.72 ? 418 TYR A CG  1 
ATOM   2986 C  CD1 . TYR A 1 430 ? 121.977 94.740  120.814 1.00 92.72 ? 418 TYR A CD1 1 
ATOM   2987 C  CD2 . TYR A 1 430 ? 121.347 95.929  122.777 1.00 92.72 ? 418 TYR A CD2 1 
ATOM   2988 C  CE1 . TYR A 1 430 ? 120.648 94.592  120.471 1.00 92.72 ? 418 TYR A CE1 1 
ATOM   2989 C  CE2 . TYR A 1 430 ? 120.015 95.786  122.441 1.00 92.72 ? 418 TYR A CE2 1 
ATOM   2990 C  CZ  . TYR A 1 430 ? 119.671 95.115  121.287 1.00 92.72 ? 418 TYR A CZ  1 
ATOM   2991 O  OH  . TYR A 1 430 ? 118.346 94.966  120.948 1.00 92.72 ? 418 TYR A OH  1 
ATOM   2992 N  N   . PRO A 1 431 ? 126.305 96.901  119.892 1.00 87.33 ? 419 PRO A N   1 
ATOM   2993 C  CA  . PRO A 1 431 ? 127.058 96.371  118.749 1.00 87.33 ? 419 PRO A CA  1 
ATOM   2994 C  C   . PRO A 1 431 ? 127.967 95.203  119.061 1.00 87.33 ? 419 PRO A C   1 
ATOM   2995 O  O   . PRO A 1 431 ? 127.930 94.206  118.344 1.00 87.33 ? 419 PRO A O   1 
ATOM   2996 C  CB  . PRO A 1 431 ? 127.909 97.570  118.295 1.00 87.33 ? 419 PRO A CB  1 
ATOM   2997 C  CG  . PRO A 1 431 ? 127.539 98.721  119.179 1.00 87.33 ? 419 PRO A CG  1 
ATOM   2998 C  CD  . PRO A 1 431 ? 126.880 98.156  120.397 1.00 87.33 ? 419 PRO A CD  1 
ATOM   2999 N  N   . SER A 1 432 ? 128.734 95.291  120.140 1.00 85.92 ? 420 SER A N   1 
ATOM   3000 C  CA  . SER A 1 432 ? 129.691 94.239  120.436 1.00 85.92 ? 420 SER A CA  1 
ATOM   3001 C  C   . SER A 1 432 ? 128.978 92.938  120.702 1.00 85.92 ? 420 SER A C   1 
ATOM   3002 O  O   . SER A 1 432 ? 129.376 91.893  120.192 1.00 85.92 ? 420 SER A O   1 
ATOM   3003 C  CB  . SER A 1 432 ? 130.543 94.618  121.646 1.00 85.92 ? 420 SER A CB  1 
ATOM   3004 O  OG  . SER A 1 432 ? 131.437 93.572  121.984 1.00 85.92 ? 420 SER A OG  1 
ATOM   3005 N  N   . PHE A 1 433 ? 127.895 93.002  121.465 1.00 90.67 ? 421 PHE A N   1 
ATOM   3006 C  CA  . PHE A 1 433 ? 127.196 91.785  121.828 1.00 90.67 ? 421 PHE A CA  1 
ATOM   3007 C  C   . PHE A 1 433 ? 126.650 91.074  120.602 1.00 90.67 ? 421 PHE A C   1 
ATOM   3008 O  O   . PHE A 1 433 ? 126.850 89.876  120.436 1.00 90.67 ? 421 PHE A O   1 
ATOM   3009 C  CB  . PHE A 1 433 ? 126.059 92.146  122.787 1.00 90.67 ? 421 PHE A CB  1 
ATOM   3010 C  CG  . PHE A 1 433 ? 125.108 91.020  123.073 1.00 90.67 ? 421 PHE A CG  1 
ATOM   3011 C  CD1 . PHE A 1 433 ? 123.828 91.028  122.542 1.00 90.67 ? 421 PHE A CD1 1 
ATOM   3012 C  CD2 . PHE A 1 433 ? 125.483 89.968  123.891 1.00 90.67 ? 421 PHE A CD2 1 
ATOM   3013 C  CE1 . PHE A 1 433 ? 122.946 90.000  122.809 1.00 90.67 ? 421 PHE A CE1 1 
ATOM   3014 C  CE2 . PHE A 1 433 ? 124.605 88.937  124.162 1.00 90.67 ? 421 PHE A CE2 1 
ATOM   3015 C  CZ  . PHE A 1 433 ? 123.334 88.953  123.621 1.00 90.67 ? 421 PHE A CZ  1 
ATOM   3016 N  N   . LEU A 1 434 ? 126.003 91.819  119.716 1.00 93.07 ? 422 LEU A N   1 
ATOM   3017 C  CA  . LEU A 1 434 ? 125.445 91.212  118.517 1.00 93.07 ? 422 LEU A CA  1 
ATOM   3018 C  C   . LEU A 1 434 ? 126.473 90.676  117.534 1.00 93.07 ? 422 LEU A C   1 
ATOM   3019 O  O   . LEU A 1 434 ? 126.328 89.559  117.045 1.00 93.07 ? 422 LEU A O   1 
ATOM   3020 C  CB  . LEU A 1 434 ? 124.501 92.184  117.809 1.00 93.07 ? 422 LEU A CB  1 
ATOM   3021 C  CG  . LEU A 1 434 ? 123.072 92.225  118.345 1.00 93.07 ? 422 LEU A CG  1 
ATOM   3022 C  CD1 . LEU A 1 434 ? 122.175 92.985  117.382 1.00 93.07 ? 422 LEU A CD1 1 
ATOM   3023 C  CD2 . LEU A 1 434 ? 122.546 90.813  118.542 1.00 93.07 ? 422 LEU A CD2 1 
ATOM   3024 N  N   . ARG A 1 435 ? 127.538 91.429  117.282 1.00 88.64 ? 423 ARG A N   1 
ATOM   3025 C  CA  . ARG A 1 435 ? 128.503 91.023  116.253 1.00 88.64 ? 423 ARG A CA  1 
ATOM   3026 C  C   . ARG A 1 435 ? 129.278 89.749  116.547 1.00 88.64 ? 423 ARG A C   1 
ATOM   3027 O  O   . ARG A 1 435 ? 129.415 88.893  115.675 1.00 88.64 ? 423 ARG A O   1 
ATOM   3028 C  CB  . ARG A 1 435 ? 129.481 92.166  115.970 1.00 88.64 ? 423 ARG A CB  1 
ATOM   3029 C  CG  . ARG A 1 435 ? 128.835 93.393  115.351 1.00 88.64 ? 423 ARG A CG  1 
ATOM   3030 C  CD  . ARG A 1 435 ? 128.314 93.103  113.955 1.00 88.64 ? 423 ARG A CD  1 
ATOM   3031 N  NE  . ARG A 1 435 ? 127.608 94.249  113.395 1.00 88.64 ? 423 ARG A NE  1 
ATOM   3032 C  CZ  . ARG A 1 435 ? 127.186 94.323  112.138 1.00 88.64 ? 423 ARG A CZ  1 
ATOM   3033 N  NH1 . ARG A 1 435 ? 127.409 93.317  111.303 1.00 88.64 ? 423 ARG A NH1 1 
ATOM   3034 N  NH2 . ARG A 1 435 ? 126.549 95.405  111.713 1.00 88.64 ? 423 ARG A NH2 1 
ATOM   3035 N  N   . LYS A 1 436 ? 129.802 89.628  117.758 1.00 86.98 ? 424 LYS A N   1 
ATOM   3036 C  CA  . LYS A 1 436 ? 130.596 88.463  118.130 1.00 86.98 ? 424 LYS A CA  1 
ATOM   3037 C  C   . LYS A 1 436 ? 129.759 87.209  117.974 1.00 86.98 ? 424 LYS A C   1 
ATOM   3038 O  O   . LYS A 1 436 ? 130.252 86.182  117.510 1.00 86.98 ? 424 LYS A O   1 
ATOM   3039 C  CB  . LYS A 1 436 ? 131.205 88.595  119.535 1.00 86.98 ? 424 LYS A CB  1 
ATOM   3040 C  CG  . LYS A 1 436 ? 130.219 88.726  120.682 1.00 86.98 ? 424 LYS A CG  1 
ATOM   3041 C  CD  . LYS A 1 436 ? 130.923 89.156  121.958 1.00 86.98 ? 424 LYS A CD  1 
ATOM   3042 C  CE  . LYS A 1 436 ? 129.945 89.296  123.112 1.00 86.98 ? 424 LYS A CE  1 
ATOM   3043 N  NZ  . LYS A 1 436 ? 130.599 89.832  124.337 1.00 86.98 ? 424 LYS A NZ  1 
ATOM   3044 N  N   . GLY A 1 437 ? 128.491 87.287  118.356 1.00 87.73 ? 425 GLY A N   1 
ATOM   3045 C  CA  . GLY A 1 437 ? 127.602 86.156  118.184 1.00 87.73 ? 425 GLY A CA  1 
ATOM   3046 C  C   . GLY A 1 437 ? 127.104 86.016  116.764 1.00 87.73 ? 425 GLY A C   1 
ATOM   3047 O  O   . GLY A 1 437 ? 127.211 86.947  115.969 1.00 87.73 ? 425 GLY A O   1 
ATOM   3048 N  N   . TYR A 1 438 ? 126.552 84.856  116.428 1.00 92.40 ? 426 TYR A N   1 
ATOM   3049 C  CA  . TYR A 1 438 ? 125.961 84.671  115.106 1.00 92.40 ? 426 TYR A CA  1 
ATOM   3050 C  C   . TYR A 1 438 ? 124.548 85.204  115.232 1.00 92.40 ? 426 TYR A C   1 
ATOM   3051 O  O   . TYR A 1 438 ? 123.778 85.191  114.277 1.00 92.40 ? 426 TYR A O   1 
ATOM   3052 C  CB  . TYR A 1 438 ? 125.957 83.195  114.716 1.00 92.40 ? 426 TYR A CB  1 
ATOM   3053 C  CG  . TYR A 1 438 ? 125.819 82.949  113.231 1.00 92.40 ? 426 TYR A CG  1 
ATOM   3054 C  CD1 . TYR A 1 438 ? 126.858 83.248  112.361 1.00 92.40 ? 426 TYR A CD1 1 
ATOM   3055 C  CD2 . TYR A 1 438 ? 124.655 82.409  112.701 1.00 92.40 ? 426 TYR A CD2 1 
ATOM   3056 C  CE1 . TYR A 1 438 ? 126.739 83.024  111.003 1.00 92.40 ? 426 TYR A CE1 1 
ATOM   3057 C  CE2 . TYR A 1 438 ? 124.527 82.182  111.344 1.00 92.40 ? 426 TYR A CE2 1 
ATOM   3058 C  CZ  . TYR A 1 438 ? 125.572 82.490  110.500 1.00 92.40 ? 426 TYR A CZ  1 
ATOM   3059 O  OH  . TYR A 1 438 ? 125.452 82.266  109.148 1.00 92.40 ? 426 TYR A OH  1 
ATOM   3060 N  N   . ARG A 1 439 ? 124.203 85.673  116.425 1.00 94.27 ? 427 ARG A N   1 
ATOM   3061 C  CA  . ARG A 1 439 ? 122.876 86.214  116.671 1.00 94.27 ? 427 ARG A CA  1 
ATOM   3062 C  C   . ARG A 1 439 ? 122.564 87.428  115.803 1.00 94.27 ? 427 ARG A C   1 
ATOM   3063 O  O   . ARG A 1 439 ? 121.433 87.584  115.370 1.00 94.27 ? 427 ARG A O   1 
ATOM   3064 C  CB  . ARG A 1 439 ? 122.735 86.572  118.151 1.00 94.27 ? 427 ARG A CB  1 
ATOM   3065 C  CG  . ARG A 1 439 ? 123.981 87.214  118.735 1.00 94.27 ? 427 ARG A CG  1 
ATOM   3066 C  CD  . ARG A 1 439 ? 123.856 87.435  120.231 1.00 94.27 ? 427 ARG A CD  1 
ATOM   3067 N  NE  . ARG A 1 439 ? 125.138 87.797  120.827 1.00 94.27 ? 427 ARG A NE  1 
ATOM   3068 C  CZ  . ARG A 1 439 ? 125.987 86.923  121.357 1.00 94.27 ? 427 ARG A CZ  1 
ATOM   3069 N  NH1 . ARG A 1 439 ? 125.691 85.630  121.370 1.00 94.27 ? 427 ARG A NH1 1 
ATOM   3070 N  NH2 . ARG A 1 439 ? 127.131 87.341  121.877 1.00 94.27 ? 427 ARG A NH2 1 
ATOM   3071 N  N   . ARG A 1 440 ? 123.544 88.296  115.560 1.00 93.64 ? 428 ARG A N   1 
ATOM   3072 C  CA  . ARG A 1 440 ? 123.308 89.437  114.683 1.00 93.64 ? 428 ARG A CA  1 
ATOM   3073 C  C   . ARG A 1 440 ? 122.953 88.917  113.312 1.00 93.64 ? 428 ARG A C   1 
ATOM   3074 O  O   . ARG A 1 440 ? 122.042 89.425  112.658 1.00 93.64 ? 428 ARG A O   1 
ATOM   3075 C  CB  . ARG A 1 440 ? 124.556 90.314  114.574 1.00 93.64 ? 428 ARG A CB  1 
ATOM   3076 C  CG  . ARG A 1 440 ? 124.316 91.711  114.015 1.00 93.64 ? 428 ARG A CG  1 
ATOM   3077 C  CD  . ARG A 1 440 ? 124.441 91.760  112.501 1.00 93.64 ? 428 ARG A CD  1 
ATOM   3078 N  NE  . ARG A 1 440 ? 123.948 93.017  111.951 1.00 93.64 ? 428 ARG A NE  1 
ATOM   3079 C  CZ  . ARG A 1 440 ? 123.884 93.290  110.653 1.00 93.64 ? 428 ARG A CZ  1 
ATOM   3080 N  NH1 . ARG A 1 440 ? 124.282 92.389  109.765 1.00 93.64 ? 428 ARG A NH1 1 
ATOM   3081 N  NH2 . ARG A 1 440 ? 123.423 94.462  110.241 1.00 93.64 ? 428 ARG A NH2 1 
ATOM   3082 N  N   . GLU A 1 441 ? 123.670 87.892  112.875 1.00 95.07 ? 429 GLU A N   1 
ATOM   3083 C  CA  . GLU A 1 441 ? 123.402 87.335  111.568 1.00 95.07 ? 429 GLU A CA  1 
ATOM   3084 C  C   . GLU A 1 441 ? 121.975 86.808  111.525 1.00 95.07 ? 429 GLU A C   1 
ATOM   3085 O  O   . GLU A 1 441 ? 121.327 86.876  110.479 1.00 95.07 ? 429 GLU A O   1 
ATOM   3086 C  CB  . GLU A 1 441 ? 124.413 86.248  111.202 1.00 95.07 ? 429 GLU A CB  1 
ATOM   3087 C  CG  . GLU A 1 441 ? 124.450 85.933  109.716 1.00 95.07 ? 429 GLU A CG  1 
ATOM   3088 C  CD  . GLU A 1 441 ? 124.810 87.143  108.877 1.00 95.07 ? 429 GLU A CD  1 
ATOM   3089 O  OE1 . GLU A 1 441 ? 124.089 87.428  107.899 1.00 95.07 ? 429 GLU A OE1 1 
ATOM   3090 O  OE2 . GLU A 1 441 ? 125.809 87.819  109.203 1.00 95.07 ? 429 GLU A OE2 1 
ATOM   3091 N  N   . ILE A 1 442 ? 121.457 86.307  112.648 1.00 96.80 ? 430 ILE A N   1 
ATOM   3092 C  CA  . ILE A 1 442 ? 120.049 85.890  112.597 1.00 96.80 ? 430 ILE A CA  1 
ATOM   3093 C  C   . ILE A 1 442 ? 119.030 86.989  112.973 1.00 96.80 ? 430 ILE A C   1 
ATOM   3094 O  O   . ILE A 1 442 ? 117.849 86.890  112.629 1.00 96.80 ? 430 ILE A O   1 
ATOM   3095 C  CB  . ILE A 1 442 ? 119.840 84.620  113.462 1.00 96.80 ? 430 ILE A CB  1 
ATOM   3096 C  CG1 . ILE A 1 442 ? 120.853 83.547  113.067 1.00 96.80 ? 430 ILE A CG1 1 
ATOM   3097 C  CG2 . ILE A 1 442 ? 118.445 84.033  113.305 1.00 96.80 ? 430 ILE A CG2 1 
ATOM   3098 C  CD1 . ILE A 1 442 ? 120.792 82.304  113.925 1.00 96.80 ? 430 ILE A CD1 1 
ATOM   3099 N  N   . PHE A 1 443 ? 119.465 88.042  113.660 1.00 97.25 ? 431 PHE A N   1 
ATOM   3100 C  CA  . PHE A 1 443 ? 118.529 89.073  114.084 1.00 97.25 ? 431 PHE A CA  1 
ATOM   3101 C  C   . PHE A 1 443 ? 117.655 89.540  112.934 1.00 97.25 ? 431 PHE A C   1 
ATOM   3102 O  O   . PHE A 1 443 ? 116.474 89.797  113.123 1.00 97.25 ? 431 PHE A O   1 
ATOM   3103 C  CB  . PHE A 1 443 ? 119.265 90.259  114.695 1.00 97.25 ? 431 PHE A CB  1 
ATOM   3104 C  CG  . PHE A 1 443 ? 118.364 91.388  115.088 1.00 97.25 ? 431 PHE A CG  1 
ATOM   3105 C  CD1 . PHE A 1 443 ? 117.652 91.337  116.274 1.00 97.25 ? 431 PHE A CD1 1 
ATOM   3106 C  CD2 . PHE A 1 443 ? 118.229 92.500  114.279 1.00 97.25 ? 431 PHE A CD2 1 
ATOM   3107 C  CE1 . PHE A 1 443 ? 116.819 92.373  116.645 1.00 97.25 ? 431 PHE A CE1 1 
ATOM   3108 C  CE2 . PHE A 1 443 ? 117.398 93.539  114.644 1.00 97.25 ? 431 PHE A CE2 1 
ATOM   3109 C  CZ  . PHE A 1 443 ? 116.692 93.478  115.828 1.00 97.25 ? 431 PHE A CZ  1 
ATOM   3110 N  N   . ILE A 1 444 ? 118.233 89.660  111.743 1.00 97.31 ? 432 ILE A N   1 
ATOM   3111 C  CA  . ILE A 1 444 ? 117.454 90.082  110.591 1.00 97.31 ? 432 ILE A CA  1 
ATOM   3112 C  C   . ILE A 1 444 ? 116.356 89.065  110.327 1.00 97.31 ? 432 ILE A C   1 
ATOM   3113 O  O   . ILE A 1 444 ? 115.205 89.433  110.096 1.00 97.31 ? 432 ILE A O   1 
ATOM   3114 C  CB  . ILE A 1 444 ? 118.317 90.225  109.327 1.00 97.31 ? 432 ILE A CB  1 
ATOM   3115 C  CG1 . ILE A 1 444 ? 119.408 91.271  109.524 1.00 97.31 ? 432 ILE A CG1 1 
ATOM   3116 C  CG2 . ILE A 1 444 ? 117.462 90.637  108.147 1.00 97.31 ? 432 ILE A CG2 1 
ATOM   3117 C  CD1 . ILE A 1 444 ? 120.169 91.590  108.257 1.00 97.31 ? 432 ILE A CD1 1 
ATOM   3118 N  N   . ALA A 1 445 ? 116.690 87.782  110.413 1.00 98.11 ? 433 ALA A N   1 
ATOM   3119 C  CA  . ALA A 1 445 ? 115.682 86.750  110.224 1.00 98.11 ? 433 ALA A CA  1 
ATOM   3120 C  C   . ALA A 1 445 ? 114.625 86.850  111.299 1.00 98.11 ? 433 ALA A C   1 
ATOM   3121 O  O   . ALA A 1 445 ? 113.440 86.721  111.020 1.00 98.11 ? 433 ALA A O   1 
ATOM   3122 C  CB  . ALA A 1 445 ? 116.319 85.373  110.245 1.00 98.11 ? 433 ALA A CB  1 
ATOM   3123 N  N   . PHE A 1 446 ? 115.051 87.092  112.531 1.00 98.07 ? 434 PHE A N   1 
ATOM   3124 C  CA  . PHE A 1 446 ? 114.113 87.177  113.638 1.00 98.07 ? 434 PHE A CA  1 
ATOM   3125 C  C   . PHE A 1 446 ? 113.137 88.332  113.462 1.00 98.07 ? 434 PHE A C   1 
ATOM   3126 O  O   . PHE A 1 446 ? 111.935 88.166  113.660 1.00 98.07 ? 434 PHE A O   1 
ATOM   3127 C  CB  . PHE A 1 446 ? 114.900 87.301  114.948 1.00 98.07 ? 434 PHE A CB  1 
ATOM   3128 C  CG  . PHE A 1 446 ? 114.144 87.952  116.070 1.00 98.07 ? 434 PHE A CG  1 
ATOM   3129 C  CD1 . PHE A 1 446 ? 113.172 87.257  116.767 1.00 98.07 ? 434 PHE A CD1 1 
ATOM   3130 C  CD2 . PHE A 1 446 ? 114.435 89.253  116.451 1.00 98.07 ? 434 PHE A CD2 1 
ATOM   3131 C  CE1 . PHE A 1 446 ? 112.486 87.855  117.805 1.00 98.07 ? 434 PHE A CE1 1 
ATOM   3132 C  CE2 . PHE A 1 446 ? 113.752 89.857  117.486 1.00 98.07 ? 434 PHE A CE2 1 
ATOM   3133 C  CZ  . PHE A 1 446 ? 112.776 89.156  118.165 1.00 98.07 ? 434 PHE A CZ  1 
ATOM   3134 N  N   . VAL A 1 447 ? 113.640 89.490  113.053 1.00 97.95 ? 435 VAL A N   1 
ATOM   3135 C  CA  . VAL A 1 447 ? 112.774 90.640  112.865 1.00 97.95 ? 435 VAL A CA  1 
ATOM   3136 C  C   . VAL A 1 447 ? 111.773 90.349  111.761 1.00 97.95 ? 435 VAL A C   1 
ATOM   3137 O  O   . VAL A 1 447 ? 110.580 90.590  111.922 1.00 97.95 ? 435 VAL A O   1 
ATOM   3138 C  CB  . VAL A 1 447 ? 113.590 91.901  112.523 1.00 97.95 ? 435 VAL A CB  1 
ATOM   3139 C  CG1 . VAL A 1 447 ? 112.697 93.013  111.994 1.00 97.95 ? 435 VAL A CG1 1 
ATOM   3140 C  CG2 . VAL A 1 447 ? 114.368 92.372  113.740 1.00 97.95 ? 435 VAL A CG2 1 
ATOM   3141 N  N   . CYS A 1 448 ? 112.244 89.768  110.663 1.00 98.48 ? 436 CYS A N   1 
ATOM   3142 C  CA  . CYS A 1 448 ? 111.358 89.457  109.546 1.00 98.48 ? 436 CYS A CA  1 
ATOM   3143 C  C   . CYS A 1 448 ? 110.300 88.431  109.919 1.00 98.48 ? 436 CYS A C   1 
ATOM   3144 O  O   . CYS A 1 448 ? 109.146 88.563  109.530 1.00 98.48 ? 436 CYS A O   1 
ATOM   3145 C  CB  . CYS A 1 448 ? 112.153 88.988  108.329 1.00 98.48 ? 436 CYS A CB  1 
ATOM   3146 S  SG  . CYS A 1 448 ? 113.200 90.262  107.590 1.00 98.48 ? 436 CYS A SG  1 
ATOM   3147 N  N   . SER A 1 449 ? 110.691 87.407  110.668 1.00 98.50 ? 437 SER A N   1 
ATOM   3148 C  CA  . SER A 1 449 ? 109.745 86.371  111.043 1.00 98.50 ? 437 SER A CA  1 
ATOM   3149 C  C   . SER A 1 449 ? 108.639 86.929  111.911 1.00 98.50 ? 437 SER A C   1 
ATOM   3150 O  O   . SER A 1 449 ? 107.473 86.627  111.695 1.00 98.50 ? 437 SER A O   1 
ATOM   3151 C  CB  . SER A 1 449 ? 110.456 85.246  111.782 1.00 98.50 ? 437 SER A CB  1 
ATOM   3152 O  OG  . SER A 1 449 ? 111.436 84.640  110.960 1.00 98.50 ? 437 SER A OG  1 
ATOM   3153 N  N   . ILE A 1 450 ? 108.994 87.756  112.887 1.00 98.36 ? 438 ILE A N   1 
ATOM   3154 C  CA  . ILE A 1 450 ? 107.978 88.385  113.725 1.00 98.36 ? 438 ILE A CA  1 
ATOM   3155 C  C   . ILE A 1 450 ? 107.115 89.330  112.903 1.00 98.36 ? 438 ILE A C   1 
ATOM   3156 O  O   . ILE A 1 450 ? 105.895 89.353  113.049 1.00 98.36 ? 438 ILE A O   1 
ATOM   3157 C  CB  . ILE A 1 450 ? 108.607 89.124  114.923 1.00 98.36 ? 438 ILE A CB  1 
ATOM   3158 C  CG1 . ILE A 1 450 ? 109.383 88.143  115.799 1.00 98.36 ? 438 ILE A CG1 1 
ATOM   3159 C  CG2 . ILE A 1 450 ? 107.543 89.820  115.757 1.00 98.36 ? 438 ILE A CG2 1 
ATOM   3160 C  CD1 . ILE A 1 450 ? 108.530 87.044  116.390 1.00 98.36 ? 438 ILE A CD1 1 
ATOM   3161 N  N   . SER A 1 451 ? 107.743 90.091  112.014 1.00 98.30 ? 439 SER A N   1 
ATOM   3162 C  CA  . SER A 1 451 ? 107.003 91.050  111.210 1.00 98.30 ? 439 SER A CA  1 
ATOM   3163 C  C   . SER A 1 451 ? 106.042 90.331  110.289 1.00 98.30 ? 439 SER A C   1 
ATOM   3164 O  O   . SER A 1 451 ? 104.967 90.842  110.003 1.00 98.30 ? 439 SER A O   1 
ATOM   3165 C  CB  . SER A 1 451 ? 107.959 91.929  110.415 1.00 98.30 ? 439 SER A CB  1 
ATOM   3166 O  OG  . SER A 1 451 ? 108.788 92.688  111.276 1.00 98.30 ? 439 SER A OG  1 
ATOM   3167 N  N   . TYR A 1 452 ? 106.422 89.150  109.815 1.00 98.68 ? 440 TYR A N   1 
ATOM   3168 C  CA  . TYR A 1 452 ? 105.521 88.359  108.988 1.00 98.68 ? 440 TYR A CA  1 
ATOM   3169 C  C   . TYR A 1 452 ? 104.351 87.840  109.803 1.00 98.68 ? 440 TYR A C   1 
ATOM   3170 O  O   . TYR A 1 452 ? 103.215 87.877  109.348 1.00 98.68 ? 440 TYR A O   1 
ATOM   3171 C  CB  . TYR A 1 452 ? 106.275 87.191  108.347 1.00 98.68 ? 440 TYR A CB  1 
ATOM   3172 C  CG  . TYR A 1 452 ? 105.411 86.242  107.551 1.00 98.68 ? 440 TYR A CG  1 
ATOM   3173 C  CD1 . TYR A 1 452 ? 104.992 86.566  106.274 1.00 98.68 ? 440 TYR A CD1 1 
ATOM   3174 C  CD2 . TYR A 1 452 ? 105.020 85.018  108.077 1.00 98.68 ? 440 TYR A CD2 1 
ATOM   3175 C  CE1 . TYR A 1 452 ? 104.202 85.704  105.542 1.00 98.68 ? 440 TYR A CE1 1 
ATOM   3176 C  CE2 . TYR A 1 452 ? 104.229 84.150  107.351 1.00 98.68 ? 440 TYR A CE2 1 
ATOM   3177 C  CZ  . TYR A 1 452 ? 103.824 84.499  106.083 1.00 98.68 ? 440 TYR A CZ  1 
ATOM   3178 O  OH  . TYR A 1 452 ? 103.037 83.642  105.350 1.00 98.68 ? 440 TYR A OH  1 
ATOM   3179 N  N   . LEU A 1 453 ? 104.623 87.360  111.010 1.00 98.62 ? 441 LEU A N   1 
ATOM   3180 C  CA  . LEU A 1 453 ? 103.564 86.824  111.853 1.00 98.62 ? 441 LEU A CA  1 
ATOM   3181 C  C   . LEU A 1 453 ? 102.536 87.868  112.264 1.00 98.62 ? 441 LEU A C   1 
ATOM   3182 O  O   . LEU A 1 453 ? 101.341 87.591  112.262 1.00 98.62 ? 441 LEU A O   1 
ATOM   3183 C  CB  . LEU A 1 453 ? 104.151 86.137  113.081 1.00 98.62 ? 441 LEU A CB  1 
ATOM   3184 C  CG  . LEU A 1 453 ? 104.944 84.863  112.789 1.00 98.62 ? 441 LEU A CG  1 
ATOM   3185 C  CD1 . LEU A 1 453 ? 105.525 84.280  114.067 1.00 98.62 ? 441 LEU A CD1 1 
ATOM   3186 C  CD2 . LEU A 1 453 ? 104.080 83.841  112.068 1.00 98.62 ? 441 LEU A CD2 1 
ATOM   3187 N  N   . LEU A 1 454 ? 102.979 89.080  112.587 1.00 98.10 ? 442 LEU A N   1 
ATOM   3188 C  CA  . LEU A 1 454 ? 102.030 90.154  112.898 1.00 98.10 ? 442 LEU A CA  1 
ATOM   3189 C  C   . LEU A 1 454 ? 101.417 90.630  111.599 1.00 98.10 ? 442 LEU A C   1 
ATOM   3190 O  O   . LEU A 1 454 ? 100.321 91.182  111.593 1.00 98.10 ? 442 LEU A O   1 
ATOM   3191 C  CB  . LEU A 1 454 ? 102.713 91.311  113.619 1.00 98.10 ? 442 LEU A CB  1 
ATOM   3192 C  CG  . LEU A 1 454 ? 102.673 91.294  115.147 1.00 98.10 ? 442 LEU A CG  1 
ATOM   3193 C  CD1 . LEU A 1 454 ? 101.232 91.248  115.627 1.00 98.10 ? 442 LEU A CD1 1 
ATOM   3194 C  CD2 . LEU A 1 454 ? 103.470 90.136  115.729 1.00 98.10 ? 442 LEU A CD2 1 
ATOM   3195 N  N   . GLY A 1 455 ? 102.119 90.414  110.493 1.00 98.42 ? 443 GLY A N   1 
ATOM   3196 C  CA  . GLY A 1 455 ? 101.603 90.778  109.185 1.00 98.42 ? 443 GLY A CA  1 
ATOM   3197 C  C   . GLY A 1 455 ? 100.391 89.953  108.850 1.00 98.42 ? 443 GLY A C   1 
ATOM   3198 O  O   . GLY A 1 455 ? 99.534  90.396  108.093 1.00 98.42 ? 443 GLY A O   1 
ATOM   3199 N  N   . LEU A 1 456 ? 100.301 88.756  109.416 1.00 98.60 ? 444 LEU A N   1 
ATOM   3200 C  CA  . LEU A 1 456 ? 99.205  87.849  109.091 1.00 98.60 ? 444 LEU A CA  1 
ATOM   3201 C  C   . LEU A 1 456 ? 97.845  88.435  109.408 1.00 98.60 ? 444 LEU A C   1 
ATOM   3202 O  O   . LEU A 1 456 ? 96.886  88.161  108.703 1.00 98.60 ? 444 LEU A O   1 
ATOM   3203 C  CB  . LEU A 1 456 ? 99.381  86.492  109.768 1.00 98.60 ? 444 LEU A CB  1 
ATOM   3204 C  CG  . LEU A 1 456 ? 100.577 85.680  109.275 1.00 98.60 ? 444 LEU A CG  1 
ATOM   3205 C  CD1 . LEU A 1 456 ? 100.659 84.349  110.004 1.00 98.60 ? 444 LEU A CD1 1 
ATOM   3206 C  CD2 . LEU A 1 456 ? 100.507 85.472  107.771 1.00 98.60 ? 444 LEU A CD2 1 
ATOM   3207 N  N   . THR A 1 457 ? 97.755  89.251  110.446 1.00 97.55 ? 445 THR A N   1 
ATOM   3208 C  CA  . THR A 1 457 ? 96.474  89.817  110.841 1.00 97.55 ? 445 THR A CA  1 
ATOM   3209 C  C   . THR A 1 457 ? 95.885  90.627  109.695 1.00 97.55 ? 445 THR A C   1 
ATOM   3210 O  O   . THR A 1 457 ? 94.671  90.655  109.518 1.00 97.55 ? 445 THR A O   1 
ATOM   3211 C  CB  . THR A 1 457 ? 96.614  90.715  112.075 1.00 97.55 ? 445 THR A CB  1 
ATOM   3212 O  OG1 . THR A 1 457 ? 97.412  91.859  111.749 1.00 97.55 ? 445 THR A OG1 1 
ATOM   3213 C  CG2 . THR A 1 457 ? 97.275  89.953  113.210 1.00 97.55 ? 445 THR A CG2 1 
ATOM   3214 N  N   . MET A 1 458 ? 96.727  91.319  108.937 1.00 97.88 ? 446 MET A N   1 
ATOM   3215 C  CA  . MET A 1 458 ? 96.252  92.082  107.786 1.00 97.88 ? 446 MET A CA  1 
ATOM   3216 C  C   . MET A 1 458 ? 96.012  91.273  106.506 1.00 97.88 ? 446 MET A C   1 
ATOM   3217 O  O   . MET A 1 458 ? 95.473  91.815  105.544 1.00 97.88 ? 446 MET A O   1 
ATOM   3218 C  CB  . MET A 1 458 ? 97.192  93.245  107.497 1.00 97.88 ? 446 MET A CB  1 
ATOM   3219 C  CG  . MET A 1 458 ? 97.347  94.211  108.653 1.00 97.88 ? 446 MET A CG  1 
ATOM   3220 S  SD  . MET A 1 458 ? 98.761  95.276  108.356 1.00 97.88 ? 446 MET A SD  1 
ATOM   3221 C  CE  . MET A 1 458 ? 99.964  94.044  107.882 1.00 97.88 ? 446 MET A CE  1 
ATOM   3222 N  N   . VAL A 1 459 ? 96.414  90.005  106.445 1.00 98.16 ? 447 VAL A N   1 
ATOM   3223 C  CA  . VAL A 1 459 ? 96.098  89.217  105.242 1.00 98.16 ? 447 VAL A CA  1 
ATOM   3224 C  C   . VAL A 1 459 ? 94.897  88.301  105.406 1.00 98.16 ? 447 VAL A C   1 
ATOM   3225 O  O   . VAL A 1 459 ? 94.675  87.418  104.584 1.00 98.16 ? 447 VAL A O   1 
ATOM   3226 C  CB  . VAL A 1 459 ? 97.305  88.463  104.644 1.00 98.16 ? 447 VAL A CB  1 
ATOM   3227 C  CG1 . VAL A 1 459 ? 98.354  89.446  104.156 1.00 98.16 ? 447 VAL A CG1 1 
ATOM   3228 C  CG2 . VAL A 1 459 ? 97.907  87.499  105.639 1.00 98.16 ? 447 VAL A CG2 1 
ATOM   3229 N  N   . THR A 1 460 ? 94.123  88.500  106.463 1.00 98.33 ? 448 THR A N   1 
ATOM   3230 C  CA  . THR A 1 460 ? 92.899  87.733  106.648 1.00 98.33 ? 448 THR A CA  1 
ATOM   3231 C  C   . THR A 1 460 ? 91.785  88.416  105.875 1.00 98.33 ? 448 THR A C   1 
ATOM   3232 O  O   . THR A 1 460 ? 92.008  89.446  105.245 1.00 98.33 ? 448 THR A O   1 
ATOM   3233 C  CB  . THR A 1 460 ? 92.495  87.640  108.125 1.00 98.33 ? 448 THR A CB  1 
ATOM   3234 O  OG1 . THR A 1 460 ? 92.148  88.942  108.611 1.00 98.33 ? 448 THR A OG1 1 
ATOM   3235 C  CG2 . THR A 1 460 ? 93.627  87.081  108.959 1.00 98.33 ? 448 THR A CG2 1 
ATOM   3236 N  N   . GLU A 1 461 ? 90.584  87.855  105.912 1.00 98.05 ? 449 GLU A N   1 
ATOM   3237 C  CA  . GLU A 1 461 ? 89.443  88.465  105.232 1.00 98.05 ? 449 GLU A CA  1 
ATOM   3238 C  C   . GLU A 1 461 ? 89.145  89.847  105.798 1.00 98.05 ? 449 GLU A C   1 
ATOM   3239 O  O   . GLU A 1 461 ? 88.784  90.751  105.056 1.00 98.05 ? 449 GLU A O   1 
ATOM   3240 C  CB  . GLU A 1 461 ? 88.213  87.575  105.351 1.00 98.05 ? 449 GLU A CB  1 
ATOM   3241 C  CG  . GLU A 1 461 ? 88.426  86.167  104.830 1.00 98.05 ? 449 GLU A CG  1 
ATOM   3242 C  CD  . GLU A 1 461 ? 87.190  85.307  104.981 1.00 98.05 ? 449 GLU A CD  1 
ATOM   3243 O  OE1 . GLU A 1 461 ? 87.308  84.069  104.868 1.00 98.05 ? 449 GLU A OE1 1 
ATOM   3244 O  OE2 . GLU A 1 461 ? 86.102  85.871  105.221 1.00 98.05 ? 449 GLU A OE2 1 
ATOM   3245 N  N   . GLY A 1 462 ? 89.297  90.020  107.104 1.00 97.13 ? 450 GLY A N   1 
ATOM   3246 C  CA  . GLY A 1 462 ? 89.049  91.301  107.747 1.00 97.13 ? 450 GLY A CA  1 
ATOM   3247 C  C   . GLY A 1 462 ? 90.332  92.080  107.856 1.00 97.13 ? 450 GLY A C   1 
ATOM   3248 O  O   . GLY A 1 462 ? 90.405  93.063  108.583 1.00 97.13 ? 450 GLY A O   1 
ATOM   3249 N  N   . GLY A 1 463 ? 91.344  91.660  107.113 1.00 97.31 ? 451 GLY A N   1 
ATOM   3250 C  CA  . GLY A 1 463 ? 92.643  92.298  107.200 1.00 97.31 ? 451 GLY A CA  1 
ATOM   3251 C  C   . GLY A 1 463 ? 92.742  93.760  106.837 1.00 97.31 ? 451 GLY A C   1 
ATOM   3252 O  O   . GLY A 1 463 ? 93.549  94.481  107.411 1.00 97.31 ? 451 GLY A O   1 
ATOM   3253 N  N   . MET A 1 464 ? 91.938  94.206  105.882 1.00 95.30 ? 452 MET A N   1 
ATOM   3254 C  CA  . MET A 1 464 ? 91.997  95.595  105.455 1.00 95.30 ? 452 MET A CA  1 
ATOM   3255 C  C   . MET A 1 464 ? 91.629  96.513  106.609 1.00 95.30 ? 452 MET A C   1 
ATOM   3256 O  O   . MET A 1 464 ? 92.253  97.545  106.812 1.00 95.30 ? 452 MET A O   1 
ATOM   3257 C  CB  . MET A 1 464 ? 91.083  95.835  104.257 1.00 95.30 ? 452 MET A CB  1 
ATOM   3258 C  CG  . MET A 1 464 ? 90.796  97.293  103.953 1.00 95.30 ? 452 MET A CG  1 
ATOM   3259 S  SD  . MET A 1 464 ? 92.249  98.308  103.626 1.00 95.30 ? 452 MET A SD  1 
ATOM   3260 C  CE  . MET A 1 464 ? 92.710  97.740  101.999 1.00 95.30 ? 452 MET A CE  1 
ATOM   3261 N  N   . TYR A 1 465 ? 90.623  96.133  107.380 1.00 96.21 ? 453 TYR A N   1 
ATOM   3262 C  CA  . TYR A 1 465 ? 90.205  96.956  108.493 1.00 96.21 ? 453 TYR A CA  1 
ATOM   3263 C  C   . TYR A 1 465 ? 91.340  97.136  109.483 1.00 96.21 ? 453 TYR A C   1 
ATOM   3264 O  O   . TYR A 1 465 ? 91.516  98.220  110.025 1.00 96.21 ? 453 TYR A O   1 
ATOM   3265 C  CB  . TYR A 1 465 ? 88.996  96.342  109.171 1.00 96.21 ? 453 TYR A CB  1 
ATOM   3266 C  CG  . TYR A 1 465 ? 87.776  96.262  108.296 1.00 96.21 ? 453 TYR A CG  1 
ATOM   3267 C  CD1 . TYR A 1 465 ? 86.994  97.380  108.065 1.00 96.21 ? 453 TYR A CD1 1 
ATOM   3268 C  CD2 . TYR A 1 465 ? 87.398  95.067  107.708 1.00 96.21 ? 453 TYR A CD2 1 
ATOM   3269 C  CE1 . TYR A 1 465 ? 85.871  97.313  107.268 1.00 96.21 ? 453 TYR A CE1 1 
ATOM   3270 C  CE2 . TYR A 1 465 ? 86.277  94.990  106.910 1.00 96.21 ? 453 TYR A CE2 1 
ATOM   3271 C  CZ  . TYR A 1 465 ? 85.517  96.118  106.692 1.00 96.21 ? 453 TYR A CZ  1 
ATOM   3272 O  OH  . TYR A 1 465 ? 84.398  96.050  105.896 1.00 96.21 ? 453 TYR A OH  1 
ATOM   3273 N  N   . VAL A 1 466 ? 92.117  96.085  109.718 1.00 97.05 ? 454 VAL A N   1 
ATOM   3274 C  CA  . VAL A 1 466 ? 93.252  96.177  110.624 1.00 97.05 ? 454 VAL A CA  1 
ATOM   3275 C  C   . VAL A 1 466 ? 94.328  97.024  109.975 1.00 97.05 ? 454 VAL A C   1 
ATOM   3276 O  O   . VAL A 1 466 ? 95.010  97.790  110.645 1.00 97.05 ? 454 VAL A O   1 
ATOM   3277 C  CB  . VAL A 1 466 ? 93.833  94.793  110.958 1.00 97.05 ? 454 VAL A CB  1 
ATOM   3278 C  CG1 . VAL A 1 466 ? 94.762  94.874  112.158 1.00 97.05 ? 454 VAL A CG1 1 
ATOM   3279 C  CG2 . VAL A 1 466 ? 92.716  93.798  111.222 1.00 97.05 ? 454 VAL A CG2 1 
ATOM   3280 N  N   . PHE A 1 467 ? 94.476  96.896  108.664 1.00 96.33 ? 455 PHE A N   1 
ATOM   3281 C  CA  . PHE A 1 467 ? 95.477  97.674  107.953 1.00 96.33 ? 455 PHE A CA  1 
ATOM   3282 C  C   . PHE A 1 467 ? 95.166  99.166  107.953 1.00 96.33 ? 455 PHE A C   1 
ATOM   3283 O  O   . PHE A 1 467 ? 96.061  99.976  108.139 1.00 96.33 ? 455 PHE A O   1 
ATOM   3284 C  CB  . PHE A 1 467 ? 95.617  97.154  106.523 1.00 96.33 ? 455 PHE A CB  1 
ATOM   3285 C  CG  . PHE A 1 467 ? 96.466  98.014  105.652 1.00 96.33 ? 455 PHE A CG  1 
ATOM   3286 C  CD1 . PHE A 1 467 ? 97.839  97.942  105.726 1.00 96.33 ? 455 PHE A CD1 1 
ATOM   3287 C  CD2 . PHE A 1 467 ? 95.889  98.897  104.759 1.00 96.33 ? 455 PHE A CD2 1 
ATOM   3288 C  CE1 . PHE A 1 467 ? 98.624  98.739  104.929 1.00 96.33 ? 455 PHE A CE1 1 
ATOM   3289 C  CE2 . PHE A 1 467 ? 96.670  99.698  103.962 1.00 96.33 ? 455 PHE A CE2 1 
ATOM   3290 C  CZ  . PHE A 1 467 ? 98.038  99.619  104.048 1.00 96.33 ? 455 PHE A CZ  1 
ATOM   3291 N  N   . GLN A 1 468 ? 93.908  99.537  107.742 1.00 93.81 ? 456 GLN A N   1 
ATOM   3292 C  CA  . GLN A 1 468 ? 93.526  100.945 107.781 1.00 93.81 ? 456 GLN A CA  1 
ATOM   3293 C  C   . GLN A 1 468 ? 93.740  101.496 109.173 1.00 93.81 ? 456 GLN A C   1 
ATOM   3294 O  O   . GLN A 1 468 ? 94.197  102.622 109.331 1.00 93.81 ? 456 GLN A O   1 
ATOM   3295 C  CB  . GLN A 1 468 ? 92.076  101.144 107.352 1.00 93.81 ? 456 GLN A CB  1 
ATOM   3296 C  CG  . GLN A 1 468 ? 91.646  102.599 107.304 1.00 93.81 ? 456 GLN A CG  1 
ATOM   3297 C  CD  . GLN A 1 468 ? 92.386  103.397 106.250 1.00 93.81 ? 456 GLN A CD  1 
ATOM   3298 O  OE1 . GLN A 1 468 ? 93.334  104.118 106.554 1.00 93.81 ? 456 GLN A OE1 1 
ATOM   3299 N  NE2 . GLN A 1 468 ? 91.949  103.279 105.002 1.00 93.81 ? 456 GLN A NE2 1 
ATOM   3300 N  N   . LEU A 1 469 ? 93.455  100.691 110.188 1.00 94.95 ? 457 LEU A N   1 
ATOM   3301 C  CA  . LEU A 1 469 ? 93.680  101.110 111.565 1.00 94.95 ? 457 LEU A CA  1 
ATOM   3302 C  C   . LEU A 1 469 ? 95.162  101.359 111.768 1.00 94.95 ? 457 LEU A C   1 
ATOM   3303 O  O   . LEU A 1 469 ? 95.549  102.368 112.352 1.00 94.95 ? 457 LEU A O   1 
ATOM   3304 C  CB  . LEU A 1 469 ? 93.178  100.023 112.504 1.00 94.95 ? 457 LEU A CB  1 
ATOM   3305 C  CG  . LEU A 1 469 ? 93.166  100.161 114.020 1.00 94.95 ? 457 LEU A CG  1 
ATOM   3306 C  CD1 . LEU A 1 469 ? 91.915  99.459  114.503 1.00 94.95 ? 457 LEU A CD1 1 
ATOM   3307 C  CD2 . LEU A 1 469 ? 94.392  99.497  114.622 1.00 94.95 ? 457 LEU A CD2 1 
ATOM   3308 N  N   . PHE A 1 470 ? 95.989  100.442 111.284 1.00 94.99 ? 458 PHE A N   1 
ATOM   3309 C  CA  . PHE A 1 470 ? 97.430  100.589 111.412 1.00 94.99 ? 458 PHE A CA  1 
ATOM   3310 C  C   . PHE A 1 470 ? 97.895  101.801 110.655 1.00 94.99 ? 458 PHE A C   1 
ATOM   3311 O  O   . PHE A 1 470 ? 98.656  102.597 111.177 1.00 94.99 ? 458 PHE A O   1 
ATOM   3312 C  CB  . PHE A 1 470 ? 98.140  99.375  110.822 1.00 94.99 ? 458 PHE A CB  1 
ATOM   3313 C  CG  . PHE A 1 470 ? 98.651  98.407  111.840 1.00 94.99 ? 458 PHE A CG  1 
ATOM   3314 C  CD1 . PHE A 1 470 ? 97.823  97.432  112.364 1.00 94.99 ? 458 PHE A CD1 1 
ATOM   3315 C  CD2 . PHE A 1 470 ? 99.969  98.456  112.255 1.00 94.99 ? 458 PHE A CD2 1 
ATOM   3316 C  CE1 . PHE A 1 470 ? 98.295  96.532  113.297 1.00 94.99 ? 458 PHE A CE1 1 
ATOM   3317 C  CE2 . PHE A 1 470 ? 100.449 97.559  113.187 1.00 94.99 ? 458 PHE A CE2 1 
ATOM   3318 C  CZ  . PHE A 1 470 ? 99.610  96.596  113.709 1.00 94.99 ? 458 PHE A CZ  1 
ATOM   3319 N  N   . ASP A 1 471 ? 97.443  101.955 109.419 1.00 91.51 ? 459 ASP A N   1 
ATOM   3320 C  CA  . ASP A 1 471 ? 97.958  103.044 108.608 1.00 91.51 ? 459 ASP A CA  1 
ATOM   3321 C  C   . ASP A 1 471 ? 97.660  104.415 109.186 1.00 91.51 ? 459 ASP A C   1 
ATOM   3322 O  O   . ASP A 1 471 ? 98.561  105.233 109.288 1.00 91.51 ? 459 ASP A O   1 
ATOM   3323 C  CB  . ASP A 1 471 ? 97.369  102.952 107.199 1.00 91.51 ? 459 ASP A CB  1 
ATOM   3324 C  CG  . ASP A 1 471 ? 98.020  103.908 106.220 1.00 91.51 ? 459 ASP A CG  1 
ATOM   3325 O  OD1 . ASP A 1 471 ? 99.154  104.366 106.469 1.00 91.51 ? 459 ASP A OD1 1 
ATOM   3326 O  OD2 . ASP A 1 471 ? 97.393  104.190 105.181 1.00 91.51 ? 459 ASP A OD2 1 
ATOM   3327 N  N   . TYR A 1 472 ? 96.428  104.674 109.600 1.00 91.27 ? 460 TYR A N   1 
ATOM   3328 C  CA  . TYR A 1 472 ? 96.167  105.962 110.212 1.00 91.27 ? 460 TYR A CA  1 
ATOM   3329 C  C   . TYR A 1 472 ? 96.827  106.154 111.562 1.00 91.27 ? 460 TYR A C   1 
ATOM   3330 O  O   . TYR A 1 472 ? 97.428  107.186 111.810 1.00 91.27 ? 460 TYR A O   1 
ATOM   3331 C  CB  . TYR A 1 472 ? 94.664  106.199 110.343 1.00 91.27 ? 460 TYR A CB  1 
ATOM   3332 C  CG  . TYR A 1 472 ? 94.303  107.551 110.919 1.00 91.27 ? 460 TYR A CG  1 
ATOM   3333 C  CD1 . TYR A 1 472 ? 94.361  108.695 110.139 1.00 91.27 ? 460 TYR A CD1 1 
ATOM   3334 C  CD2 . TYR A 1 472 ? 93.903  107.682 112.243 1.00 91.27 ? 460 TYR A CD2 1 
ATOM   3335 C  CE1 . TYR A 1 472 ? 94.034  109.930 110.661 1.00 91.27 ? 460 TYR A CE1 1 
ATOM   3336 C  CE2 . TYR A 1 472 ? 93.572  108.912 112.772 1.00 91.27 ? 460 TYR A CE2 1 
ATOM   3337 C  CZ  . TYR A 1 472 ? 93.639  110.032 111.976 1.00 91.27 ? 460 TYR A CZ  1 
ATOM   3338 O  OH  . TYR A 1 472 ? 93.310  111.260 112.499 1.00 91.27 ? 460 TYR A OH  1 
ATOM   3339 N  N   . TYR A 1 473 ? 96.687  105.177 112.448 1.00 93.56 ? 461 TYR A N   1 
ATOM   3340 C  CA  . TYR A 1 473 ? 97.272  105.278 113.788 1.00 93.56 ? 461 TYR A CA  1 
ATOM   3341 C  C   . TYR A 1 473 ? 98.781  105.146 113.951 1.00 93.56 ? 461 TYR A C   1 
ATOM   3342 O  O   . TYR A 1 473 ? 99.380  105.854 114.754 1.00 93.56 ? 461 TYR A O   1 
ATOM   3343 C  CB  . TYR A 1 473 ? 96.503  104.427 114.785 1.00 93.56 ? 461 TYR A CB  1 
ATOM   3344 C  CG  . TYR A 1 473 ? 95.260  105.124 115.270 1.00 93.56 ? 461 TYR A CG  1 
ATOM   3345 C  CD1 . TYR A 1 473 ? 95.340  106.362 115.888 1.00 93.56 ? 461 TYR A CD1 1 
ATOM   3346 C  CD2 . TYR A 1 473 ? 94.010  104.554 115.105 1.00 93.56 ? 461 TYR A CD2 1 
ATOM   3347 C  CE1 . TYR A 1 473 ? 94.207  107.011 116.332 1.00 93.56 ? 461 TYR A CE1 1 
ATOM   3348 C  CE2 . TYR A 1 473 ? 92.873  105.191 115.556 1.00 93.56 ? 461 TYR A CE2 1 
ATOM   3349 C  CZ  . TYR A 1 473 ? 92.977  106.421 116.162 1.00 93.56 ? 461 TYR A CZ  1 
ATOM   3350 O  OH  . TYR A 1 473 ? 91.844  107.058 116.600 1.00 93.56 ? 461 TYR A OH  1 
ATOM   3351 N  N   . ALA A 1 474 ? 99.394  104.242 113.201 1.00 92.46 ? 462 ALA A N   1 
ATOM   3352 C  CA  . ALA A 1 474 ? 100.828 104.005 113.331 1.00 92.46 ? 462 ALA A CA  1 
ATOM   3353 C  C   . ALA A 1 474 ? 101.549 104.546 112.124 1.00 92.46 ? 462 ALA A C   1 
ATOM   3354 O  O   . ALA A 1 474 ? 101.064 104.404 111.004 1.00 92.46 ? 462 ALA A O   1 
ATOM   3355 C  CB  . ALA A 1 474 ? 101.107 102.526 113.482 1.00 92.46 ? 462 ALA A CB  1 
ATOM   3356 N  N   . ALA A 1 475 ? 102.687 105.190 112.346 1.00 84.74 ? 463 ALA A N   1 
ATOM   3357 C  CA  . ALA A 1 475 ? 103.450 105.792 111.253 1.00 84.74 ? 463 ALA A CA  1 
ATOM   3358 C  C   . ALA A 1 475 ? 102.674 106.841 110.482 1.00 84.74 ? 463 ALA A C   1 
ATOM   3359 O  O   . ALA A 1 475 ? 103.058 107.166 109.363 1.00 84.74 ? 463 ALA A O   1 
ATOM   3360 C  CB  . ALA A 1 475 ? 104.043 104.743 110.329 1.00 84.74 ? 463 ALA A CB  1 
ATOM   3361 N  N   . SER A 1 476 ? 101.588 107.360 111.056 1.00 82.92 ? 464 SER A N   1 
ATOM   3362 C  CA  . SER A 1 476 ? 100.845 108.455 110.440 1.00 82.92 ? 464 SER A CA  1 
ATOM   3363 C  C   . SER A 1 476 ? 99.984  108.892 111.598 1.00 82.92 ? 464 SER A C   1 
ATOM   3364 O  O   . SER A 1 476 ? 99.944  108.209 112.609 1.00 82.92 ? 464 SER A O   1 
ATOM   3365 C  CB  . SER A 1 476 ? 99.963  107.992 109.294 1.00 82.92 ? 464 SER A CB  1 
ATOM   3366 O  OG  . SER A 1 476 ? 100.721 107.571 108.176 1.00 82.92 ? 464 SER A OG  1 
ATOM   3367 N  N   . GLY A 1 477 ? 99.291  110.011 111.495 1.00 83.44 ? 465 GLY A N   1 
ATOM   3368 C  CA  . GLY A 1 477 ? 98.381  110.373 112.566 1.00 83.44 ? 465 GLY A CA  1 
ATOM   3369 C  C   . GLY A 1 477 ? 98.941  111.399 113.524 1.00 83.44 ? 465 GLY A C   1 
ATOM   3370 O  O   . GLY A 1 477 ? 99.204  112.516 113.129 1.00 83.44 ? 465 GLY A O   1 
ATOM   3371 N  N   . VAL A 1 478 ? 99.110  111.059 114.792 1.00 88.08 ? 466 VAL A N   1 
ATOM   3372 C  CA  . VAL A 1 478 ? 99.712  112.039 115.666 1.00 88.08 ? 466 VAL A CA  1 
ATOM   3373 C  C   . VAL A 1 478 ? 101.102 111.545 116.034 1.00 88.08 ? 466 VAL A C   1 
ATOM   3374 O  O   . VAL A 1 478 ? 101.967 112.345 116.351 1.00 88.08 ? 466 VAL A O   1 
ATOM   3375 C  CB  . VAL A 1 478 ? 98.860  112.263 116.913 1.00 88.08 ? 466 VAL A CB  1 
ATOM   3376 C  CG1 . VAL A 1 478 ? 97.671  113.146 116.575 1.00 88.08 ? 466 VAL A CG1 1 
ATOM   3377 C  CG2 . VAL A 1 478 ? 98.386  110.927 117.437 1.00 88.08 ? 466 VAL A CG2 1 
ATOM   3378 N  N   . CYS A 1 479 ? 101.314 110.233 116.044 1.00 93.14 ? 467 CYS A N   1 
ATOM   3379 C  CA  . CYS A 1 479 ? 102.644 109.696 116.306 1.00 93.14 ? 467 CYS A CA  1 
ATOM   3380 C  C   . CYS A 1 479 ? 103.761 110.415 115.536 1.00 93.14 ? 467 CYS A C   1 
ATOM   3381 O  O   . CYS A 1 479 ? 104.729 110.846 116.150 1.00 93.14 ? 467 CYS A O   1 
ATOM   3382 C  CB  . CYS A 1 479 ? 102.696 108.194 116.042 1.00 93.14 ? 467 CYS A CB  1 
ATOM   3383 S  SG  . CYS A 1 479 ? 102.354 107.711 114.340 1.00 93.14 ? 467 CYS A SG  1 
ATOM   3384 N  N   . LEU A 1 480 ? 103.638 110.564 114.215 1.00 93.13 ? 468 LEU A N   1 
ATOM   3385 C  CA  . LEU A 1 480 ? 104.679 111.284 113.491 1.00 93.13 ? 468 LEU A CA  1 
ATOM   3386 C  C   . LEU A 1 480 ? 104.739 112.737 113.919 1.00 93.13 ? 468 LEU A C   1 
ATOM   3387 O  O   . LEU A 1 480 ? 105.820 113.297 114.049 1.00 93.13 ? 468 LEU A O   1 
ATOM   3388 C  CB  . LEU A 1 480 ? 104.487 111.174 111.982 1.00 93.13 ? 468 LEU A CB  1 
ATOM   3389 C  CG  . LEU A 1 480 ? 104.860 109.834 111.354 1.00 93.13 ? 468 LEU A CG  1 
ATOM   3390 C  CD1 . LEU A 1 480 ? 104.675 109.897 109.849 1.00 93.13 ? 468 LEU A CD1 1 
ATOM   3391 C  CD2 . LEU A 1 480 ? 106.298 109.483 111.690 1.00 93.13 ? 468 LEU A CD2 1 
ATOM   3392 N  N   . LEU A 1 481 ? 103.584 113.349 114.148 1.00 91.23 ? 469 LEU A N   1 
ATOM   3393 C  CA  . LEU A 1 481 ? 103.550 114.741 114.577 1.00 91.23 ? 469 LEU A CA  1 
ATOM   3394 C  C   . LEU A 1 481 ? 104.248 114.924 115.918 1.00 91.23 ? 469 LEU A C   1 
ATOM   3395 O  O   . LEU A 1 481 ? 104.979 115.890 116.107 1.00 91.23 ? 469 LEU A O   1 
ATOM   3396 C  CB  . LEU A 1 481 ? 102.110 115.244 114.686 1.00 91.23 ? 469 LEU A CB  1 
ATOM   3397 C  CG  . LEU A 1 481 ? 101.262 115.332 113.419 1.00 91.23 ? 469 LEU A CG  1 
ATOM   3398 C  CD1 . LEU A 1 481 ? 99.821  115.649 113.785 1.00 91.23 ? 469 LEU A CD1 1 
ATOM   3399 C  CD2 . LEU A 1 481 ? 101.818 116.385 112.476 1.00 91.23 ? 469 LEU A CD2 1 
ATOM   3400 N  N   . TRP A 1 482 ? 104.029 114.003 116.851 1.00 93.62 ? 470 TRP A N   1 
ATOM   3401 C  CA  . TRP A 1 482 ? 104.651 114.117 118.161 1.00 93.62 ? 470 TRP A CA  1 
ATOM   3402 C  C   . TRP A 1 482 ? 106.160 114.042 118.046 1.00 93.62 ? 470 TRP A C   1 
ATOM   3403 O  O   . TRP A 1 482 ? 106.874 114.844 118.644 1.00 93.62 ? 470 TRP A O   1 
ATOM   3404 C  CB  . TRP A 1 482 ? 104.163 112.991 119.071 1.00 93.62 ? 470 TRP A CB  1 
ATOM   3405 C  CG  . TRP A 1 482 ? 104.639 113.067 120.495 1.00 93.62 ? 470 TRP A CG  1 
ATOM   3406 C  CD1 . TRP A 1 482 ? 105.890 112.786 120.963 1.00 93.62 ? 470 TRP A CD1 1 
ATOM   3407 C  CD2 . TRP A 1 482 ? 103.856 113.419 121.640 1.00 93.62 ? 470 TRP A CD2 1 
ATOM   3408 N  NE1 . TRP A 1 482 ? 105.939 112.960 122.322 1.00 93.62 ? 470 TRP A NE1 1 
ATOM   3409 C  CE2 . TRP A 1 482 ? 104.702 113.346 122.764 1.00 93.62 ? 470 TRP A CE2 1 
ATOM   3410 C  CE3 . TRP A 1 482 ? 102.523 113.796 121.824 1.00 93.62 ? 470 TRP A CE3 1 
ATOM   3411 C  CZ2 . TRP A 1 482 ? 104.260 113.635 124.050 1.00 93.62 ? 470 TRP A CZ2 1 
ATOM   3412 C  CZ3 . TRP A 1 482 ? 102.086 114.082 123.101 1.00 93.62 ? 470 TRP A CZ3 1 
ATOM   3413 C  CH2 . TRP A 1 482 ? 102.952 114.000 124.198 1.00 93.62 ? 470 TRP A CH2 1 
ATOM   3414 N  N   . VAL A 1 483 ? 106.658 113.075 117.289 1.00 96.59 ? 471 VAL A N   1 
ATOM   3415 C  CA  . VAL A 1 483 ? 108.099 112.911 117.153 1.00 96.59 ? 471 VAL A CA  1 
ATOM   3416 C  C   . VAL A 1 483 ? 108.688 114.126 116.446 1.00 96.59 ? 471 VAL A C   1 
ATOM   3417 O  O   . VAL A 1 483 ? 109.745 114.619 116.831 1.00 96.59 ? 471 VAL A O   1 
ATOM   3418 C  CB  . VAL A 1 483 ? 108.458 111.607 116.415 1.00 96.59 ? 471 VAL A CB  1 
ATOM   3419 C  CG1 . VAL A 1 483 ? 109.964 111.404 116.381 1.00 96.59 ? 471 VAL A CG1 1 
ATOM   3420 C  CG2 . VAL A 1 483 ? 107.794 110.422 117.096 1.00 96.59 ? 471 VAL A CG2 1 
ATOM   3421 N  N   . ALA A 1 484 ? 107.993 114.633 115.433 1.00 95.90 ? 472 ALA A N   1 
ATOM   3422 C  CA  . ALA A 1 484 ? 108.499 115.778 114.687 1.00 95.90 ? 472 ALA A CA  1 
ATOM   3423 C  C   . ALA A 1 484 ? 108.632 117.015 115.551 1.00 95.90 ? 472 ALA A C   1 
ATOM   3424 O  O   . ALA A 1 484 ? 109.641 117.708 115.494 1.00 95.90 ? 472 ALA A O   1 
ATOM   3425 C  CB  . ALA A 1 484 ? 107.607 116.076 113.498 1.00 95.90 ? 472 ALA A CB  1 
ATOM   3426 N  N   . PHE A 1 485 ? 107.629 117.279 116.377 1.00 96.67 ? 473 PHE A N   1 
ATOM   3427 C  CA  . PHE A 1 485 ? 107.690 118.444 117.231 1.00 96.67 ? 473 PHE A CA  1 
ATOM   3428 C  C   . PHE A 1 485 ? 108.855 118.293 118.178 1.00 96.67 ? 473 PHE A C   1 
ATOM   3429 O  O   . PHE A 1 485 ? 109.612 119.231 118.386 1.00 96.67 ? 473 PHE A O   1 
ATOM   3430 C  CB  . PHE A 1 485 ? 106.399 118.620 118.026 1.00 96.67 ? 473 PHE A CB  1 
ATOM   3431 C  CG  . PHE A 1 485 ? 106.505 119.634 119.128 1.00 96.67 ? 473 PHE A CG  1 
ATOM   3432 C  CD1 . PHE A 1 485 ? 106.730 120.968 118.839 1.00 96.67 ? 473 PHE A CD1 1 
ATOM   3433 C  CD2 . PHE A 1 485 ? 106.387 119.253 120.451 1.00 96.67 ? 473 PHE A CD2 1 
ATOM   3434 C  CE1 . PHE A 1 485 ? 106.838 121.902 119.850 1.00 96.67 ? 473 PHE A CE1 1 
ATOM   3435 C  CE2 . PHE A 1 485 ? 106.493 120.181 121.467 1.00 96.67 ? 473 PHE A CE2 1 
ATOM   3436 C  CZ  . PHE A 1 485 ? 106.716 121.508 121.166 1.00 96.67 ? 473 PHE A CZ  1 
ATOM   3437 N  N   . PHE A 1 486 ? 109.016 117.104 118.738 1.00 98.14 ? 474 PHE A N   1 
ATOM   3438 C  CA  . PHE A 1 486 ? 110.079 116.896 119.709 1.00 98.14 ? 474 PHE A CA  1 
ATOM   3439 C  C   . PHE A 1 486 ? 111.481 117.045 119.137 1.00 98.14 ? 474 PHE A C   1 
ATOM   3440 O  O   . PHE A 1 486 ? 112.331 117.673 119.756 1.00 98.14 ? 474 PHE A O   1 
ATOM   3441 C  CB  . PHE A 1 486 ? 109.898 115.563 120.434 1.00 98.14 ? 474 PHE A CB  1 
ATOM   3442 C  CG  . PHE A 1 486 ? 109.023 115.660 121.650 1.00 98.14 ? 474 PHE A CG  1 
ATOM   3443 C  CD1 . PHE A 1 486 ? 107.733 116.145 121.556 1.00 98.14 ? 474 PHE A CD1 1 
ATOM   3444 C  CD2 . PHE A 1 486 ? 109.495 115.277 122.888 1.00 98.14 ? 474 PHE A CD2 1 
ATOM   3445 C  CE1 . PHE A 1 486 ? 106.929 116.246 122.672 1.00 98.14 ? 474 PHE A CE1 1 
ATOM   3446 C  CE2 . PHE A 1 486 ? 108.698 115.370 124.011 1.00 98.14 ? 474 PHE A CE2 1 
ATOM   3447 C  CZ  . PHE A 1 486 ? 107.412 115.856 123.903 1.00 98.14 ? 474 PHE A CZ  1 
ATOM   3448 N  N   . GLU A 1 487 ? 111.727 116.496 117.954 1.00 97.94 ? 475 GLU A N   1 
ATOM   3449 C  CA  . GLU A 1 487 ? 113.037 116.687 117.341 1.00 97.94 ? 475 GLU A CA  1 
ATOM   3450 C  C   . GLU A 1 487 ? 113.308 118.137 116.977 1.00 97.94 ? 475 GLU A C   1 
ATOM   3451 O  O   . GLU A 1 487 ? 114.410 118.630 117.192 1.00 97.94 ? 475 GLU A O   1 
ATOM   3452 C  CB  . GLU A 1 487 ? 113.304 115.718 116.183 1.00 97.94 ? 475 GLU A CB  1 
ATOM   3453 C  CG  . GLU A 1 487 ? 112.360 115.763 115.004 1.00 97.94 ? 475 GLU A CG  1 
ATOM   3454 C  CD  . GLU A 1 487 ? 112.492 114.520 114.151 1.00 97.94 ? 475 GLU A CD  1 
ATOM   3455 O  OE1 . GLU A 1 487 ? 112.422 114.629 112.913 1.00 97.94 ? 475 GLU A OE1 1 
ATOM   3456 O  OE2 . GLU A 1 487 ? 112.687 113.428 114.724 1.00 97.94 ? 475 GLU A OE2 1 
ATOM   3457 N  N   . CYS A 1 488 ? 112.311 118.832 116.446 1.00 98.28 ? 476 CYS A N   1 
ATOM   3458 C  CA  . CYS A 1 488 ? 112.486 120.238 116.115 1.00 98.28 ? 476 CYS A CA  1 
ATOM   3459 C  C   . CYS A 1 488 ? 112.705 121.047 117.372 1.00 98.28 ? 476 CYS A C   1 
ATOM   3460 O  O   . CYS A 1 488 ? 113.557 121.925 117.405 1.00 98.28 ? 476 CYS A O   1 
ATOM   3461 C  CB  . CYS A 1 488 ? 111.283 120.765 115.354 1.00 98.28 ? 476 CYS A CB  1 
ATOM   3462 S  SG  . CYS A 1 488 ? 111.138 120.057 113.706 1.00 98.28 ? 476 CYS A SG  1 
ATOM   3463 N  N   . PHE A 1 489 ? 111.954 120.735 118.419 1.00 97.80 ? 477 PHE A N   1 
ATOM   3464 C  CA  . PHE A 1 489 ? 112.084 121.470 119.664 1.00 97.80 ? 477 PHE A CA  1 
ATOM   3465 C  C   . PHE A 1 489 ? 113.479 121.320 120.258 1.00 97.80 ? 477 PHE A C   1 
ATOM   3466 O  O   . PHE A 1 489 ? 114.079 122.297 120.689 1.00 97.80 ? 477 PHE A O   1 
ATOM   3467 C  CB  . PHE A 1 489 ? 111.026 120.988 120.661 1.00 97.80 ? 477 PHE A CB  1 
ATOM   3468 C  CG  . PHE A 1 489 ? 111.296 121.381 122.085 1.00 97.80 ? 477 PHE A CG  1 
ATOM   3469 C  CD1 . PHE A 1 489 ? 111.062 122.673 122.517 1.00 97.80 ? 477 PHE A CD1 1 
ATOM   3470 C  CD2 . PHE A 1 489 ? 111.758 120.446 122.998 1.00 97.80 ? 477 PHE A CD2 1 
ATOM   3471 C  CE1 . PHE A 1 489 ? 111.306 123.034 123.827 1.00 97.80 ? 477 PHE A CE1 1 
ATOM   3472 C  CE2 . PHE A 1 489 ? 112.005 120.801 124.308 1.00 97.80 ? 477 PHE A CE2 1 
ATOM   3473 C  CZ  . PHE A 1 489 ? 111.776 122.096 124.725 1.00 97.80 ? 477 PHE A CZ  1 
ATOM   3474 N  N   . VAL A 1 490 ? 114.008 120.104 120.271 1.00 97.91 ? 478 VAL A N   1 
ATOM   3475 C  CA  . VAL A 1 490 ? 115.335 119.903 120.816 1.00 97.91 ? 478 VAL A CA  1 
ATOM   3476 C  C   . VAL A 1 490 ? 116.426 120.602 120.020 1.00 97.91 ? 478 VAL A C   1 
ATOM   3477 O  O   . VAL A 1 490 ? 117.257 121.305 120.585 1.00 97.91 ? 478 VAL A O   1 
ATOM   3478 C  CB  . VAL A 1 490 ? 115.665 118.406 120.885 1.00 97.91 ? 478 VAL A CB  1 
ATOM   3479 C  CG1 . VAL A 1 490 ? 117.130 118.186 121.208 1.00 97.91 ? 478 VAL A CG1 1 
ATOM   3480 C  CG2 . VAL A 1 490 ? 114.787 117.737 121.920 1.00 97.91 ? 478 VAL A CG2 1 
ATOM   3481 N  N   . ILE A 1 491 ? 116.404 120.452 118.703 1.00 97.33 ? 479 ILE A N   1 
ATOM   3482 C  CA  . ILE A 1 491 ? 117.462 121.041 117.904 1.00 97.33 ? 479 ILE A CA  1 
ATOM   3483 C  C   . ILE A 1 491 ? 117.403 122.550 117.961 1.00 97.33 ? 479 ILE A C   1 
ATOM   3484 O  O   . ILE A 1 491 ? 118.406 123.211 118.221 1.00 97.33 ? 479 ILE A O   1 
ATOM   3485 C  CB  . ILE A 1 491 ? 117.340 120.593 116.437 1.00 97.33 ? 479 ILE A CB  1 
ATOM   3486 C  CG1 . ILE A 1 491 ? 117.772 119.137 116.292 1.00 97.33 ? 479 ILE A CG1 1 
ATOM   3487 C  CG2 . ILE A 1 491 ? 118.189 121.466 115.529 1.00 97.33 ? 479 ILE A CG2 1 
ATOM   3488 C  CD1 . ILE A 1 491 ? 119.249 118.926 116.524 1.00 97.33 ? 479 ILE A CD1 1 
ATOM   3489 N  N   . ALA A 1 492 ? 116.215 123.099 117.760 1.00 97.00 ? 480 ALA A N   1 
ATOM   3490 C  CA  . ALA A 1 492 ? 116.057 124.546 117.757 1.00 97.00 ? 480 ALA A CA  1 
ATOM   3491 C  C   . ALA A 1 492 ? 116.222 125.233 119.084 1.00 97.00 ? 480 ALA A C   1 
ATOM   3492 O  O   . ALA A 1 492 ? 116.853 126.283 119.170 1.00 97.00 ? 480 ALA A O   1 
ATOM   3493 C  CB  . ALA A 1 492 ? 114.719 124.911 117.166 1.00 97.00 ? 480 ALA A CB  1 
ATOM   3494 N  N   . TRP A 1 493 ? 115.662 124.649 120.131 1.00 96.35 ? 481 TRP A N   1 
ATOM   3495 C  CA  . TRP A 1 493 ? 115.681 125.331 121.414 1.00 96.35 ? 481 TRP A CA  1 
ATOM   3496 C  C   . TRP A 1 493 ? 116.758 124.854 122.364 1.00 96.35 ? 481 TRP A C   1 
ATOM   3497 O  O   . TRP A 1 493 ? 117.341 125.670 123.075 1.00 96.35 ? 481 TRP A O   1 
ATOM   3498 C  CB  . TRP A 1 493 ? 114.305 125.260 122.073 1.00 96.35 ? 481 TRP A CB  1 
ATOM   3499 C  CG  . TRP A 1 493 ? 113.226 125.849 121.225 1.00 96.35 ? 481 TRP A CG  1 
ATOM   3500 C  CD1 . TRP A 1 493 ? 112.338 125.175 120.439 1.00 96.35 ? 481 TRP A CD1 1 
ATOM   3501 C  CD2 . TRP A 1 493 ? 112.928 127.239 121.064 1.00 96.35 ? 481 TRP A CD2 1 
ATOM   3502 N  NE1 . TRP A 1 493 ? 111.501 126.058 119.806 1.00 96.35 ? 481 TRP A NE1 1 
ATOM   3503 C  CE2 . TRP A 1 493 ? 111.843 127.333 120.173 1.00 96.35 ? 481 TRP A CE2 1 
ATOM   3504 C  CE3 . TRP A 1 493 ? 113.471 128.414 121.591 1.00 96.35 ? 481 TRP A CE3 1 
ATOM   3505 C  CZ2 . TRP A 1 493 ? 111.290 128.554 119.797 1.00 96.35 ? 481 TRP A CZ2 1 
ATOM   3506 C  CZ3 . TRP A 1 493 ? 112.921 129.624 121.216 1.00 96.35 ? 481 TRP A CZ3 1 
ATOM   3507 C  CH2 . TRP A 1 493 ? 111.843 129.685 120.327 1.00 96.35 ? 481 TRP A CH2 1 
ATOM   3508 N  N   . ILE A 1 494 ? 117.039 123.556 122.405 1.00 95.25 ? 482 ILE A N   1 
ATOM   3509 C  CA  . ILE A 1 494 ? 118.035 123.139 123.392 1.00 95.25 ? 482 ILE A CA  1 
ATOM   3510 C  C   . ILE A 1 494 ? 119.451 123.112 122.835 1.00 95.25 ? 482 ILE A C   1 
ATOM   3511 O  O   . ILE A 1 494 ? 120.355 123.713 123.415 1.00 95.25 ? 482 ILE A O   1 
ATOM   3512 C  CB  . ILE A 1 494 ? 117.696 121.746 123.958 1.00 95.25 ? 482 ILE A CB  1 
ATOM   3513 C  CG1 . ILE A 1 494 ? 116.218 121.662 124.343 1.00 95.25 ? 482 ILE A CG1 1 
ATOM   3514 C  CG2 . ILE A 1 494 ? 118.583 121.418 125.149 1.00 95.25 ? 482 ILE A CG2 1 
ATOM   3515 C  CD1 . ILE A 1 494 ? 115.852 122.496 125.551 1.00 95.25 ? 482 ILE A CD1 1 
ATOM   3516 N  N   . TYR A 1 495 ? 119.655 122.433 121.711 1.00 94.15 ? 483 TYR A N   1 
ATOM   3517 C  CA  . TYR A 1 495 ? 120.970 122.425 121.069 1.00 94.15 ? 483 TYR A CA  1 
ATOM   3518 C  C   . TYR A 1 495 ? 121.298 123.809 120.546 1.00 94.15 ? 483 TYR A C   1 
ATOM   3519 O  O   . TYR A 1 495 ? 122.443 124.253 120.623 1.00 94.15 ? 483 TYR A O   1 
ATOM   3520 C  CB  . TYR A 1 495 ? 121.037 121.386 119.947 1.00 94.15 ? 483 TYR A CB  1 
ATOM   3521 C  CG  . TYR A 1 495 ? 122.402 121.264 119.316 1.00 94.15 ? 483 TYR A CG  1 
ATOM   3522 C  CD1 . TYR A 1 495 ? 123.419 120.568 119.952 1.00 94.15 ? 483 TYR A CD1 1 
ATOM   3523 C  CD2 . TYR A 1 495 ? 122.676 121.846 118.087 1.00 94.15 ? 483 TYR A CD2 1 
ATOM   3524 C  CE1 . TYR A 1 495 ? 124.672 120.455 119.382 1.00 94.15 ? 483 TYR A CE1 1 
ATOM   3525 C  CE2 . TYR A 1 495 ? 123.926 121.741 117.512 1.00 94.15 ? 483 TYR A CE2 1 
ATOM   3526 C  CZ  . TYR A 1 495 ? 124.918 121.043 118.161 1.00 94.15 ? 483 TYR A CZ  1 
ATOM   3527 O  OH  . TYR A 1 495 ? 126.163 120.936 117.587 1.00 94.15 ? 483 TYR A OH  1 
ATOM   3528 N  N   . GLY A 1 496 ? 120.294 124.498 120.015 1.00 93.94 ? 484 GLY A N   1 
ATOM   3529 C  CA  . GLY A 1 496 ? 120.513 125.810 119.437 1.00 93.94 ? 484 GLY A CA  1 
ATOM   3530 C  C   . GLY A 1 496 ? 120.469 125.711 117.931 1.00 93.94 ? 484 GLY A C   1 
ATOM   3531 O  O   . GLY A 1 496 ? 121.370 125.145 117.317 1.00 93.94 ? 484 GLY A O   1 
ATOM   3532 N  N   . GLY A 1 497 ? 119.412 126.244 117.328 1.00 93.39 ? 485 GLY A N   1 
ATOM   3533 C  CA  . GLY A 1 497 ? 119.290 126.228 115.881 1.00 93.39 ? 485 GLY A CA  1 
ATOM   3534 C  C   . GLY A 1 497 ? 120.386 127.047 115.251 1.00 93.39 ? 485 GLY A C   1 
ATOM   3535 O  O   . GLY A 1 497 ? 120.953 126.658 114.234 1.00 93.39 ? 485 GLY A O   1 
ATOM   3536 N  N   . ASP A 1 498 ? 120.686 128.189 115.854 1.00 93.48 ? 486 ASP A N   1 
ATOM   3537 C  CA  . ASP A 1 498 ? 121.746 129.034 115.340 1.00 93.48 ? 486 ASP A CA  1 
ATOM   3538 C  C   . ASP A 1 498 ? 123.076 128.339 115.537 1.00 93.48 ? 486 ASP A C   1 
ATOM   3539 O  O   . ASP A 1 498 ? 123.956 128.441 114.693 1.00 93.48 ? 486 ASP A O   1 
ATOM   3540 C  CB  . ASP A 1 498 ? 121.759 130.379 116.060 1.00 93.48 ? 486 ASP A CB  1 
ATOM   3541 C  CG  . ASP A 1 498 ? 122.734 131.361 115.442 1.00 93.48 ? 486 ASP A CG  1 
ATOM   3542 O  OD1 . ASP A 1 498 ? 122.918 131.325 114.206 1.00 93.48 ? 486 ASP A OD1 1 
ATOM   3543 O  OD2 . ASP A 1 498 ? 123.310 132.177 116.192 1.00 93.48 ? 486 ASP A OD2 1 
ATOM   3544 N  N   . ASN A 1 499 ? 123.199 127.570 116.615 1.00 91.74 ? 487 ASN A N   1 
ATOM   3545 C  CA  . ASN A 1 499 ? 124.424 126.814 116.871 1.00 91.74 ? 487 ASN A CA  1 
ATOM   3546 C  C   . ASN A 1 499 ? 124.579 125.702 115.843 1.00 91.74 ? 487 ASN A C   1 
ATOM   3547 O  O   . ASN A 1 499 ? 125.683 125.441 115.362 1.00 91.74 ? 487 ASN A O   1 
ATOM   3548 C  CB  . ASN A 1 499 ? 124.386 126.225 118.281 1.00 91.74 ? 487 ASN A CB  1 
ATOM   3549 C  CG  . ASN A 1 499 ? 125.656 125.482 118.643 1.00 91.74 ? 487 ASN A CG  1 
ATOM   3550 O  OD1 . ASN A 1 499 ? 126.751 125.848 118.213 1.00 91.74 ? 487 ASN A OD1 1 
ATOM   3551 N  ND2 . ASN A 1 499 ? 125.518 124.440 119.455 1.00 91.74 ? 487 ASN A ND2 1 
ATOM   3552 N  N   . LEU A 1 500 ? 123.478 125.045 115.495 1.00 94.21 ? 488 LEU A N   1 
ATOM   3553 C  CA  . LEU A 1 500 ? 123.529 123.995 114.480 1.00 94.21 ? 488 LEU A CA  1 
ATOM   3554 C  C   . LEU A 1 500 ? 123.952 124.594 113.159 1.00 94.21 ? 488 LEU A C   1 
ATOM   3555 O  O   . LEU A 1 500 ? 124.694 123.977 112.417 1.00 94.21 ? 488 LEU A O   1 
ATOM   3556 C  CB  . LEU A 1 500 ? 122.195 123.267 114.327 1.00 94.21 ? 488 LEU A CB  1 
ATOM   3557 C  CG  . LEU A 1 500 ? 122.274 122.061 113.386 1.00 94.21 ? 488 LEU A CG  1 
ATOM   3558 C  CD1 . LEU A 1 500 ? 123.200 120.984 113.927 1.00 94.21 ? 488 LEU A CD1 1 
ATOM   3559 C  CD2 . LEU A 1 500 ? 120.908 121.487 113.072 1.00 94.21 ? 488 LEU A CD2 1 
ATOM   3560 N  N   . TYR A 1 501 ? 123.500 125.808 112.873 1.00 95.09 ? 489 TYR A N   1 
ATOM   3561 C  CA  . TYR A 1 501 ? 123.833 126.458 111.615 1.00 95.09 ? 489 TYR A CA  1 
ATOM   3562 C  C   . TYR A 1 501 ? 125.334 126.598 111.506 1.00 95.09 ? 489 TYR A C   1 
ATOM   3563 O  O   . TYR A 1 501 ? 125.887 126.434 110.428 1.00 95.09 ? 489 TYR A O   1 
ATOM   3564 C  CB  . TYR A 1 501 ? 123.210 127.843 111.562 1.00 95.09 ? 489 TYR A CB  1 
ATOM   3565 C  CG  . TYR A 1 501 ? 121.967 127.945 110.729 1.00 95.09 ? 489 TYR A CG  1 
ATOM   3566 C  CD1 . TYR A 1 501 ? 121.075 126.889 110.641 1.00 95.09 ? 489 TYR A CD1 1 
ATOM   3567 C  CD2 . TYR A 1 501 ? 121.678 129.111 110.041 1.00 95.09 ? 489 TYR A CD2 1 
ATOM   3568 C  CE1 . TYR A 1 501 ? 119.932 126.989 109.876 1.00 95.09 ? 489 TYR A CE1 1 
ATOM   3569 C  CE2 . TYR A 1 501 ? 120.539 129.223 109.277 1.00 95.09 ? 489 TYR A CE2 1 
ATOM   3570 C  CZ  . TYR A 1 501 ? 119.674 128.159 109.197 1.00 95.09 ? 489 TYR A CZ  1 
ATOM   3571 O  OH  . TYR A 1 501 ? 118.541 128.279 108.441 1.00 95.09 ? 489 TYR A OH  1 
ATOM   3572 N  N   . ASP A 1 502 ? 126.001 126.907 112.611 1.00 93.29 ? 490 ASP A N   1 
ATOM   3573 C  CA  . ASP A 1 502 ? 127.454 126.986 112.591 1.00 93.29 ? 490 ASP A CA  1 
ATOM   3574 C  C   . ASP A 1 502 ? 128.026 125.629 112.230 1.00 93.29 ? 490 ASP A C   1 
ATOM   3575 O  O   . ASP A 1 502 ? 128.977 125.541 111.458 1.00 93.29 ? 490 ASP A O   1 
ATOM   3576 C  CB  . ASP A 1 502 ? 127.984 127.410 113.958 1.00 93.29 ? 490 ASP A CB  1 
ATOM   3577 C  CG  . ASP A 1 502 ? 127.347 128.687 114.462 1.00 93.29 ? 490 ASP A CG  1 
ATOM   3578 O  OD1 . ASP A 1 502 ? 126.953 129.529 113.630 1.00 93.29 ? 490 ASP A OD1 1 
ATOM   3579 O  OD2 . ASP A 1 502 ? 127.247 128.854 115.695 1.00 93.29 ? 490 ASP A OD2 1 
ATOM   3580 N  N   . GLY A 1 503 ? 127.469 124.564 112.792 1.00 91.56 ? 491 GLY A N   1 
ATOM   3581 C  CA  . GLY A 1 503 ? 127.914 123.230 112.427 1.00 91.56 ? 491 GLY A CA  1 
ATOM   3582 C  C   . GLY A 1 503 ? 127.637 122.878 110.978 1.00 91.56 ? 491 GLY A C   1 
ATOM   3583 O  O   . GLY A 1 503 ? 128.492 122.307 110.305 1.00 91.56 ? 491 GLY A O   1 
ATOM   3584 N  N   . ILE A 1 504 ? 126.453 123.228 110.484 1.00 95.17 ? 492 ILE A N   1 
ATOM   3585 C  CA  . ILE A 1 504 ? 126.085 122.910 109.112 1.00 95.17 ? 492 ILE A CA  1 
ATOM   3586 C  C   . ILE A 1 504 ? 126.994 123.663 108.176 1.00 95.17 ? 492 ILE A C   1 
ATOM   3587 O  O   . ILE A 1 504 ? 127.498 123.103 107.212 1.00 95.17 ? 492 ILE A O   1 
ATOM   3588 C  CB  . ILE A 1 504 ? 124.644 123.348 108.788 1.00 95.17 ? 492 ILE A CB  1 
ATOM   3589 C  CG1 . ILE A 1 504 ? 123.645 122.725 109.755 1.00 95.17 ? 492 ILE A CG1 1 
ATOM   3590 C  CG2 . ILE A 1 504 ? 124.269 122.970 107.367 1.00 95.17 ? 492 ILE A CG2 1 
ATOM   3591 C  CD1 . ILE A 1 504 ? 122.231 123.223 109.556 1.00 95.17 ? 492 ILE A CD1 1 
ATOM   3592 N  N   . GLU A 1 505 ? 127.213 124.938 108.461 1.00 95.60 ? 493 GLU A N   1 
ATOM   3593 C  CA  . GLU A 1 505 ? 128.011 125.760 107.569 1.00 95.60 ? 493 GLU A CA  1 
ATOM   3594 C  C   . GLU A 1 505 ? 129.398 125.171 107.407 1.00 95.60 ? 493 GLU A C   1 
ATOM   3595 O  O   . GLU A 1 505 ? 129.955 125.208 106.318 1.00 95.60 ? 493 GLU A O   1 
ATOM   3596 C  CB  . GLU A 1 505 ? 128.033 127.235 107.997 1.00 95.60 ? 493 GLU A CB  1 
ATOM   3597 C  CG  . GLU A 1 505 ? 129.117 127.645 108.976 1.00 95.60 ? 493 GLU A CG  1 
ATOM   3598 C  CD  . GLU A 1 505 ? 129.074 129.123 109.299 1.00 95.60 ? 493 GLU A CD  1 
ATOM   3599 O  OE1 . GLU A 1 505 ? 128.576 129.899 108.458 1.00 95.60 ? 493 GLU A OE1 1 
ATOM   3600 O  OE2 . GLU A 1 505 ? 129.544 129.508 110.389 1.00 95.60 ? 493 GLU A OE2 1 
ATOM   3601 N  N   . ASP A 1 506 ? 129.969 124.634 108.479 1.00 92.91 ? 494 ASP A N   1 
ATOM   3602 C  CA  . ASP A 1 506 ? 131.258 123.979 108.348 1.00 92.91 ? 494 ASP A CA  1 
ATOM   3603 C  C   . ASP A 1 506 ? 131.143 122.763 107.435 1.00 92.91 ? 494 ASP A C   1 
ATOM   3604 O  O   . ASP A 1 506 ? 131.980 122.559 106.557 1.00 92.91 ? 494 ASP A O   1 
ATOM   3605 C  CB  . ASP A 1 506 ? 131.759 123.545 109.724 1.00 92.91 ? 494 ASP A CB  1 
ATOM   3606 C  CG  . ASP A 1 506 ? 133.198 123.070 109.702 1.00 92.91 ? 494 ASP A CG  1 
ATOM   3607 O  OD1 . ASP A 1 506 ? 133.957 123.492 108.804 1.00 92.91 ? 494 ASP A OD1 1 
ATOM   3608 O  OD2 . ASP A 1 506 ? 133.575 122.282 110.594 1.00 92.91 ? 494 ASP A OD2 1 
ATOM   3609 N  N   . MET A 1 507 ? 130.104 121.958 107.631 1.00 94.06 ? 495 MET A N   1 
ATOM   3610 C  CA  . MET A 1 507 ? 129.917 120.756 106.816 1.00 94.06 ? 495 MET A CA  1 
ATOM   3611 C  C   . MET A 1 507 ? 129.620 120.978 105.332 1.00 94.06 ? 495 MET A C   1 
ATOM   3612 O  O   . MET A 1 507 ? 130.185 120.301 104.481 1.00 94.06 ? 495 MET A O   1 
ATOM   3613 C  CB  . MET A 1 507 ? 128.845 119.862 107.438 1.00 94.06 ? 495 MET A CB  1 
ATOM   3614 C  CG  . MET A 1 507 ? 129.279 119.216 108.741 1.00 94.06 ? 495 MET A CG  1 
ATOM   3615 S  SD  . MET A 1 507 ? 128.043 118.081 109.390 1.00 94.06 ? 495 MET A SD  1 
ATOM   3616 C  CE  . MET A 1 507 ? 126.732 119.221 109.811 1.00 94.06 ? 495 MET A CE  1 
ATOM   3617 N  N   . ILE A 1 508 ? 128.738 121.918 105.017 1.00 95.42 ? 496 ILE A N   1 
ATOM   3618 C  CA  . ILE A 1 508 ? 128.373 122.147 103.622 1.00 95.42 ? 496 ILE A CA  1 
ATOM   3619 C  C   . ILE A 1 508 ? 129.214 123.240 102.982 1.00 95.42 ? 496 ILE A C   1 
ATOM   3620 O  O   . ILE A 1 508 ? 129.097 123.492 101.783 1.00 95.42 ? 496 ILE A O   1 
ATOM   3621 C  CB  . ILE A 1 508 ? 126.870 122.448 103.454 1.00 95.42 ? 496 ILE A CB  1 
ATOM   3622 C  CG1 . ILE A 1 508 ? 126.521 123.815 104.035 1.00 95.42 ? 496 ILE A CG1 1 
ATOM   3623 C  CG2 . ILE A 1 508 ? 126.030 121.354 104.096 1.00 95.42 ? 496 ILE A CG2 1 
ATOM   3624 C  CD1 . ILE A 1 508 ? 125.066 124.188 103.877 1.00 95.42 ? 496 ILE A CD1 1 
ATOM   3625 N  N   . GLY A 1 509 ? 130.065 123.886 103.768 1.00 94.42 ? 497 GLY A N   1 
ATOM   3626 C  CA  . GLY A 1 509 ? 130.947 124.914 103.237 1.00 94.42 ? 497 GLY A CA  1 
ATOM   3627 C  C   . GLY A 1 509 ? 130.386 126.321 103.122 1.00 94.42 ? 497 GLY A C   1 
ATOM   3628 O  O   . GLY A 1 509 ? 131.111 127.231 102.721 1.00 94.42 ? 497 GLY A O   1 
ATOM   3629 N  N   . TYR A 1 510 ? 129.121 126.519 103.476 1.00 96.07 ? 498 TYR A N   1 
ATOM   3630 C  CA  . TYR A 1 510 ? 128.534 127.861 103.461 1.00 96.07 ? 498 TYR A CA  1 
ATOM   3631 C  C   . TYR A 1 510 ? 127.370 127.953 104.435 1.00 96.07 ? 498 TYR A C   1 
ATOM   3632 O  O   . TYR A 1 510 ? 126.768 126.945 104.777 1.00 96.07 ? 498 TYR A O   1 
ATOM   3633 C  CB  . TYR A 1 510 ? 128.081 128.263 102.052 1.00 96.07 ? 498 TYR A CB  1 
ATOM   3634 C  CG  . TYR A 1 510 ? 127.020 127.373 101.446 1.00 96.07 ? 498 TYR A CG  1 
ATOM   3635 C  CD1 . TYR A 1 510 ? 127.369 126.243 100.728 1.00 96.07 ? 498 TYR A CD1 1 
ATOM   3636 C  CD2 . TYR A 1 510 ? 125.670 127.675 101.576 1.00 96.07 ? 498 TYR A CD2 1 
ATOM   3637 C  CE1 . TYR A 1 510 ? 126.409 125.431 100.170 1.00 96.07 ? 498 TYR A CE1 1 
ATOM   3638 C  CE2 . TYR A 1 510 ? 124.701 126.864 101.022 1.00 96.07 ? 498 TYR A CE2 1 
ATOM   3639 C  CZ  . TYR A 1 510 ? 125.079 125.743 100.318 1.00 96.07 ? 498 TYR A CZ  1 
ATOM   3640 O  OH  . TYR A 1 510 ? 124.128 124.926 99.755  1.00 96.07 ? 498 TYR A OH  1 
ATOM   3641 N  N   . ARG A 1 511 ? 127.036 129.162 104.867 1.00 94.77 ? 499 ARG A N   1 
ATOM   3642 C  CA  . ARG A 1 511 ? 125.919 129.334 105.783 1.00 94.77 ? 499 ARG A CA  1 
ATOM   3643 C  C   . ARG A 1 511 ? 124.610 129.039 105.072 1.00 94.77 ? 499 ARG A C   1 
ATOM   3644 O  O   . ARG A 1 511 ? 124.358 129.566 103.991 1.00 94.77 ? 499 ARG A O   1 
ATOM   3645 C  CB  . ARG A 1 511 ? 125.914 130.766 106.322 1.00 94.77 ? 499 ARG A CB  1 
ATOM   3646 C  CG  . ARG A 1 511 ? 124.719 131.130 107.188 1.00 94.77 ? 499 ARG A CG  1 
ATOM   3647 C  CD  . ARG A 1 511 ? 124.857 130.596 108.601 1.00 94.77 ? 499 ARG A CD  1 
ATOM   3648 N  NE  . ARG A 1 511 ? 125.989 131.195 109.298 1.00 94.77 ? 499 ARG A NE  1 
ATOM   3649 C  CZ  . ARG A 1 511 ? 126.244 131.022 110.590 1.00 94.77 ? 499 ARG A CZ  1 
ATOM   3650 N  NH1 . ARG A 1 511 ? 125.440 130.273 111.328 1.00 94.77 ? 499 ARG A NH1 1 
ATOM   3651 N  NH2 . ARG A 1 511 ? 127.297 131.604 111.146 1.00 94.77 ? 499 ARG A NH2 1 
ATOM   3652 N  N   . PRO A 1 512 ? 123.758 128.202 105.681 1.00 94.25 ? 500 PRO A N   1 
ATOM   3653 C  CA  . PRO A 1 512 ? 122.442 127.957 105.085 1.00 94.25 ? 500 PRO A CA  1 
ATOM   3654 C  C   . PRO A 1 512 ? 121.531 129.166 105.229 1.00 94.25 ? 500 PRO A C   1 
ATOM   3655 O  O   . PRO A 1 512 ? 121.684 129.941 106.170 1.00 94.25 ? 500 PRO A O   1 
ATOM   3656 C  CB  . PRO A 1 512 ? 121.897 126.774 105.889 1.00 94.25 ? 500 PRO A CB  1 
ATOM   3657 C  CG  . PRO A 1 512 ? 122.701 126.737 107.143 1.00 94.25 ? 500 PRO A CG  1 
ATOM   3658 C  CD  . PRO A 1 512 ? 124.048 127.287 106.798 1.00 94.25 ? 500 PRO A CD  1 
ATOM   3659 N  N   . GLY A 1 513 ? 120.594 129.333 104.305 1.00 91.61 ? 501 GLY A N   1 
ATOM   3660 C  CA  . GLY A 1 513 ? 119.661 130.443 104.381 1.00 91.61 ? 501 GLY A CA  1 
ATOM   3661 C  C   . GLY A 1 513 ? 118.767 130.337 105.596 1.00 91.61 ? 501 GLY A C   1 
ATOM   3662 O  O   . GLY A 1 513 ? 118.395 129.231 105.979 1.00 91.61 ? 501 GLY A O   1 
ATOM   3663 N  N   . PRO A 1 514 ? 118.416 131.478 106.209 1.00 94.50 ? 502 PRO A N   1 
ATOM   3664 C  CA  . PRO A 1 514 ? 117.596 131.480 107.428 1.00 94.50 ? 502 PRO A CA  1 
ATOM   3665 C  C   . PRO A 1 514 ? 116.305 130.693 107.305 1.00 94.50 ? 502 PRO A C   1 
ATOM   3666 O  O   . PRO A 1 514 ? 115.662 130.481 108.331 1.00 94.50 ? 502 PRO A O   1 
ATOM   3667 C  CB  . PRO A 1 514 ? 117.289 132.966 107.644 1.00 94.50 ? 502 PRO A CB  1 
ATOM   3668 C  CG  . PRO A 1 514 ? 117.559 133.623 106.331 1.00 94.50 ? 502 PRO A CG  1 
ATOM   3669 C  CD  . PRO A 1 514 ? 118.680 132.839 105.721 1.00 94.50 ? 502 PRO A CD  1 
ATOM   3670 N  N   . TRP A 1 515 ? 115.927 130.250 106.115 1.00 95.89 ? 503 TRP A N   1 
ATOM   3671 C  CA  . TRP A 1 515 ? 114.726 129.434 105.946 1.00 95.89 ? 503 TRP A CA  1 
ATOM   3672 C  C   . TRP A 1 515 ? 114.566 128.340 106.994 1.00 95.89 ? 503 TRP A C   1 
ATOM   3673 O  O   . TRP A 1 515 ? 113.572 128.316 107.717 1.00 95.89 ? 503 TRP A O   1 
ATOM   3674 C  CB  . TRP A 1 515 ? 114.717 128.820 104.549 1.00 95.89 ? 503 TRP A CB  1 
ATOM   3675 C  CG  . TRP A 1 515 ? 113.598 127.862 104.295 1.00 95.89 ? 503 TRP A CG  1 
ATOM   3676 C  CD1 . TRP A 1 515 ? 112.303 127.970 104.717 1.00 95.89 ? 503 TRP A CD1 1 
ATOM   3677 C  CD2 . TRP A 1 515 ? 113.670 126.656 103.531 1.00 95.89 ? 503 TRP A CD2 1 
ATOM   3678 N  NE1 . TRP A 1 515 ? 111.573 126.896 104.276 1.00 95.89 ? 503 TRP A NE1 1 
ATOM   3679 C  CE2 . TRP A 1 515 ? 112.388 126.076 103.542 1.00 95.89 ? 503 TRP A CE2 1 
ATOM   3680 C  CE3 . TRP A 1 515 ? 114.697 126.008 102.841 1.00 95.89 ? 503 TRP A CE3 1 
ATOM   3681 C  CZ2 . TRP A 1 515 ? 112.107 124.881 102.890 1.00 95.89 ? 503 TRP A CZ2 1 
ATOM   3682 C  CZ3 . TRP A 1 515 ? 114.415 124.827 102.196 1.00 95.89 ? 503 TRP A CZ3 1 
ATOM   3683 C  CH2 . TRP A 1 515 ? 113.132 124.273 102.226 1.00 95.89 ? 503 TRP A CH2 1 
ATOM   3684 N  N   . MET A 1 516 ? 115.531 127.434 107.085 1.00 95.70 ? 504 MET A N   1 
ATOM   3685 C  CA  . MET A 1 516 ? 115.424 126.302 108.011 1.00 95.70 ? 504 MET A CA  1 
ATOM   3686 C  C   . MET A 1 516 ? 115.373 126.642 109.485 1.00 95.70 ? 504 MET A C   1 
ATOM   3687 O  O   . MET A 1 516 ? 114.642 126.008 110.235 1.00 95.70 ? 504 MET A O   1 
ATOM   3688 C  CB  . MET A 1 516 ? 116.577 125.338 107.784 1.00 95.70 ? 504 MET A CB  1 
ATOM   3689 C  CG  . MET A 1 516 ? 116.539 124.633 106.446 1.00 95.70 ? 504 MET A CG  1 
ATOM   3690 S  SD  . MET A 1 516 ? 117.910 123.480 106.385 1.00 95.70 ? 504 MET A SD  1 
ATOM   3691 C  CE  . MET A 1 516 ? 119.240 124.640 106.096 1.00 95.70 ? 504 MET A CE  1 
ATOM   3692 N  N   . LYS A 1 517 ? 116.145 127.627 109.914 1.00 95.74 ? 505 LYS A N   1 
ATOM   3693 C  CA  . LYS A 1 517 ? 116.216 127.932 111.336 1.00 95.74 ? 505 LYS A CA  1 
ATOM   3694 C  C   . LYS A 1 517 ? 114.864 128.331 111.897 1.00 95.74 ? 505 LYS A C   1 
ATOM   3695 O  O   . LYS A 1 517 ? 114.490 127.904 112.984 1.00 95.74 ? 505 LYS A O   1 
ATOM   3696 C  CB  . LYS A 1 517 ? 117.228 129.050 111.577 1.00 95.74 ? 505 LYS A CB  1 
ATOM   3697 C  CG  . LYS A 1 517 ? 117.498 129.366 113.035 1.00 95.74 ? 505 LYS A CG  1 
ATOM   3698 C  CD  . LYS A 1 517 ? 118.764 130.190 113.172 1.00 95.74 ? 505 LYS A CD  1 
ATOM   3699 C  CE  . LYS A 1 517 ? 118.754 131.378 112.226 1.00 95.74 ? 505 LYS A CE  1 
ATOM   3700 N  NZ  . LYS A 1 517 ? 120.041 132.123 112.279 1.00 95.74 ? 505 LYS A NZ  1 
ATOM   3701 N  N   . TYR A 1 518 ? 114.119 129.132 111.152 1.00 97.21 ? 506 TYR A N   1 
ATOM   3702 C  CA  . TYR A 1 518 ? 112.823 129.577 111.630 1.00 97.21 ? 506 TYR A CA  1 
ATOM   3703 C  C   . TYR A 1 518 ? 111.799 128.461 111.558 1.00 97.21 ? 506 TYR A C   1 
ATOM   3704 O  O   . TYR A 1 518 ? 110.829 128.462 112.309 1.00 97.21 ? 506 TYR A O   1 
ATOM   3705 C  CB  . TYR A 1 518 ? 112.358 130.813 110.866 1.00 97.21 ? 506 TYR A CB  1 
ATOM   3706 C  CG  . TYR A 1 518 ? 113.124 132.056 111.252 1.00 97.21 ? 506 TYR A CG  1 
ATOM   3707 C  CD1 . TYR A 1 518 ? 114.278 132.424 110.576 1.00 97.21 ? 506 TYR A CD1 1 
ATOM   3708 C  CD2 . TYR A 1 518 ? 112.701 132.852 112.306 1.00 97.21 ? 506 TYR A CD2 1 
ATOM   3709 C  CE1 . TYR A 1 518 ? 114.986 133.555 110.932 1.00 97.21 ? 506 TYR A CE1 1 
ATOM   3710 C  CE2 . TYR A 1 518 ? 113.401 133.986 112.669 1.00 97.21 ? 506 TYR A CE2 1 
ATOM   3711 C  CZ  . TYR A 1 518 ? 114.542 134.332 111.979 1.00 97.21 ? 506 TYR A CZ  1 
ATOM   3712 O  OH  . TYR A 1 518 ? 115.241 135.461 112.338 1.00 97.21 ? 506 TYR A OH  1 
ATOM   3713 N  N   . SER A 1 519 ? 112.010 127.502 110.667 1.00 97.58 ? 507 SER A N   1 
ATOM   3714 C  CA  . SER A 1 519 ? 111.109 126.369 110.587 1.00 97.58 ? 507 SER A CA  1 
ATOM   3715 C  C   . SER A 1 519 ? 111.255 125.427 111.769 1.00 97.58 ? 507 SER A C   1 
ATOM   3716 O  O   . SER A 1 519 ? 110.265 124.984 112.328 1.00 97.58 ? 507 SER A O   1 
ATOM   3717 C  CB  . SER A 1 519 ? 111.365 125.599 109.302 1.00 97.58 ? 507 SER A CB  1 
ATOM   3718 O  OG  . SER A 1 519 ? 111.277 126.451 108.174 1.00 97.58 ? 507 SER A OG  1 
ATOM   3719 N  N   . TRP A 1 520 ? 112.486 125.141 112.170 1.00 97.70 ? 508 TRP A N   1 
ATOM   3720 C  CA  . TRP A 1 520 ? 112.704 124.215 113.271 1.00 97.70 ? 508 TRP A CA  1 
ATOM   3721 C  C   . TRP A 1 520 ? 112.286 124.861 114.575 1.00 97.70 ? 508 TRP A C   1 
ATOM   3722 O  O   . TRP A 1 520 ? 111.810 124.184 115.482 1.00 97.70 ? 508 TRP A O   1 
ATOM   3723 C  CB  . TRP A 1 520 ? 114.169 123.804 113.369 1.00 97.70 ? 508 TRP A CB  1 
ATOM   3724 C  CG  . TRP A 1 520 ? 114.705 123.130 112.163 1.00 97.70 ? 508 TRP A CG  1 
ATOM   3725 C  CD1 . TRP A 1 520 ? 114.033 122.303 111.315 1.00 97.70 ? 508 TRP A CD1 1 
ATOM   3726 C  CD2 . TRP A 1 520 ? 116.046 123.206 111.676 1.00 97.70 ? 508 TRP A CD2 1 
ATOM   3727 N  NE1 . TRP A 1 520 ? 114.871 121.868 110.319 1.00 97.70 ? 508 TRP A NE1 1 
ATOM   3728 C  CE2 . TRP A 1 520 ? 116.114 122.409 110.519 1.00 97.70 ? 508 TRP A CE2 1 
ATOM   3729 C  CE3 . TRP A 1 520 ? 117.194 123.877 112.103 1.00 97.70 ? 508 TRP A CE3 1 
ATOM   3730 C  CZ2 . TRP A 1 520 ? 117.285 122.262 109.786 1.00 97.70 ? 508 TRP A CZ2 1 
ATOM   3731 C  CZ3 . TRP A 1 520 ? 118.354 123.732 111.373 1.00 97.70 ? 508 TRP A CZ3 1 
ATOM   3732 C  CH2 . TRP A 1 520 ? 118.392 122.931 110.228 1.00 97.70 ? 508 TRP A CH2 1 
ATOM   3733 N  N   . ALA A 1 521 ? 112.476 126.171 114.680 1.00 97.97 ? 509 ALA A N   1 
ATOM   3734 C  CA  . ALA A 1 521 ? 112.123 126.881 115.904 1.00 97.97 ? 509 ALA A CA  1 
ATOM   3735 C  C   . ALA A 1 521 ? 110.637 127.142 116.048 1.00 97.97 ? 509 ALA A C   1 
ATOM   3736 O  O   . ALA A 1 521 ? 110.035 126.734 117.033 1.00 97.97 ? 509 ALA A O   1 
ATOM   3737 C  CB  . ALA A 1 521 ? 112.898 128.182 116.001 1.00 97.97 ? 509 ALA A CB  1 
ATOM   3738 N  N   . VAL A 1 522 ? 110.048 127.862 115.101 1.00 97.48 ? 510 VAL A N   1 
ATOM   3739 C  CA  . VAL A 1 522 ? 108.638 128.215 115.220 1.00 97.48 ? 510 VAL A CA  1 
ATOM   3740 C  C   . VAL A 1 522 ? 107.658 127.507 114.291 1.00 97.48 ? 510 VAL A C   1 
ATOM   3741 O  O   . VAL A 1 522 ? 106.672 126.945 114.757 1.00 97.48 ? 510 VAL A O   1 
ATOM   3742 C  CB  . VAL A 1 522 ? 108.453 129.731 115.011 1.00 97.48 ? 510 VAL A CB  1 
ATOM   3743 C  CG1 . VAL A 1 522 ? 107.043 130.159 115.383 1.00 97.48 ? 510 VAL A CG1 1 
ATOM   3744 C  CG2 . VAL A 1 522 ? 109.475 130.509 115.825 1.00 97.48 ? 510 VAL A CG2 1 
ATOM   3745 N  N   . ILE A 1 523 ? 107.930 127.481 112.990 1.00 97.01 ? 511 ILE A N   1 
ATOM   3746 C  CA  . ILE A 1 523 ? 106.937 126.935 112.050 1.00 97.01 ? 511 ILE A CA  1 
ATOM   3747 C  C   . ILE A 1 523 ? 106.563 125.463 112.202 1.00 97.01 ? 511 ILE A C   1 
ATOM   3748 O  O   . ILE A 1 523 ? 105.382 125.133 112.232 1.00 97.01 ? 511 ILE A O   1 
ATOM   3749 C  CB  . ILE A 1 523 ? 107.387 127.168 110.590 1.00 97.01 ? 511 ILE A CB  1 
ATOM   3750 C  CG1 . ILE A 1 523 ? 107.886 128.602 110.402 1.00 97.01 ? 511 ILE A CG1 1 
ATOM   3751 C  CG2 . ILE A 1 523 ? 106.261 126.860 109.614 1.00 97.01 ? 511 ILE A CG2 1 
ATOM   3752 C  CD1 . ILE A 1 523 ? 106.807 129.653 110.547 1.00 97.01 ? 511 ILE A CD1 1 
ATOM   3753 N  N   . THR A 1 524 ? 107.541 124.577 112.331 1.00 96.03 ? 512 THR A N   1 
ATOM   3754 C  CA  . THR A 1 524 ? 107.216 123.173 112.566 1.00 96.03 ? 512 THR A CA  1 
ATOM   3755 C  C   . THR A 1 524 ? 106.565 122.925 113.924 1.00 96.03 ? 512 THR A C   1 
ATOM   3756 O  O   . THR A 1 524 ? 105.583 122.194 114.011 1.00 96.03 ? 512 THR A O   1 
ATOM   3757 C  CB  . THR A 1 524 ? 108.420 122.236 112.350 1.00 96.03 ? 512 THR A CB  1 
ATOM   3758 O  OG1 . THR A 1 524 ? 109.073 122.573 111.121 1.00 96.03 ? 512 THR A OG1 1 
ATOM   3759 C  CG2 . THR A 1 524 ? 107.968 120.786 112.303 1.00 96.03 ? 512 THR A CG2 1 
ATOM   3760 N  N   . PRO A 1 525 ? 107.084 123.554 114.992 1.00 96.51 ? 513 PRO A N   1 
ATOM   3761 C  CA  . PRO A 1 525 ? 106.377 123.333 116.248 1.00 96.51 ? 513 PRO A CA  1 
ATOM   3762 C  C   . PRO A 1 525 ? 104.931 123.802 116.233 1.00 96.51 ? 513 PRO A C   1 
ATOM   3763 O  O   . PRO A 1 525 ? 104.062 123.043 116.651 1.00 96.51 ? 513 PRO A O   1 
ATOM   3764 C  CB  . PRO A 1 525 ? 107.192 124.158 117.228 1.00 96.51 ? 513 PRO A CB  1 
ATOM   3765 C  CG  . PRO A 1 525 ? 108.574 123.946 116.743 1.00 96.51 ? 513 PRO A CG  1 
ATOM   3766 C  CD  . PRO A 1 525 ? 108.441 124.068 115.251 1.00 96.51 ? 513 PRO A CD  1 
ATOM   3767 N  N   . VAL A 1 526 ? 104.666 125.015 115.764 1.00 95.72 ? 514 VAL A N   1 
ATOM   3768 C  CA  . VAL A 1 526 ? 103.310 125.532 115.809 1.00 95.72 ? 514 VAL A CA  1 
ATOM   3769 C  C   . VAL A 1 526 ? 102.385 124.627 115.014 1.00 95.72 ? 514 VAL A C   1 
ATOM   3770 O  O   . VAL A 1 526 ? 101.297 124.287 115.467 1.00 95.72 ? 514 VAL A O   1 
ATOM   3771 C  CB  . VAL A 1 526 ? 103.237 126.972 115.263 1.00 95.72 ? 514 VAL A CB  1 
ATOM   3772 C  CG1 . VAL A 1 526 ? 101.799 127.388 114.993 1.00 95.72 ? 514 VAL A CG1 1 
ATOM   3773 C  CG2 . VAL A 1 526 ? 103.892 127.936 116.238 1.00 95.72 ? 514 VAL A CG2 1 
ATOM   3774 N  N   . LEU A 1 527 ? 102.825 124.211 113.834 1.00 92.20 ? 515 LEU A N   1 
ATOM   3775 C  CA  . LEU A 1 527 ? 102.006 123.339 113.005 1.00 92.20 ? 515 LEU A CA  1 
ATOM   3776 C  C   . LEU A 1 527 ? 101.706 122.023 113.704 1.00 92.20 ? 515 LEU A C   1 
ATOM   3777 O  O   . LEU A 1 527 ? 100.549 121.627 113.799 1.00 92.20 ? 515 LEU A O   1 
ATOM   3778 C  CB  . LEU A 1 527 ? 102.656 123.097 111.645 1.00 92.20 ? 515 LEU A CB  1 
ATOM   3779 C  CG  . LEU A 1 527 ? 102.402 124.182 110.598 1.00 92.20 ? 515 LEU A CG  1 
ATOM   3780 C  CD1 . LEU A 1 527 ? 103.186 123.909 109.326 1.00 92.20 ? 515 LEU A CD1 1 
ATOM   3781 C  CD2 . LEU A 1 527 ? 100.915 124.283 110.300 1.00 92.20 ? 515 LEU A CD2 1 
ATOM   3782 N  N   . CYS A 1 528 ? 102.735 121.339 114.191 1.00 91.91 ? 516 CYS A N   1 
ATOM   3783 C  CA  . CYS A 1 528 ? 102.513 120.038 114.813 1.00 91.91 ? 516 CYS A CA  1 
ATOM   3784 C  C   . CYS A 1 528 ? 101.649 120.087 116.075 1.00 91.91 ? 516 CYS A C   1 
ATOM   3785 O  O   . CYS A 1 528 ? 100.717 119.297 116.217 1.00 91.91 ? 516 CYS A O   1 
ATOM   3786 C  CB  . CYS A 1 528 ? 103.848 119.373 115.135 1.00 91.91 ? 516 CYS A CB  1 
ATOM   3787 S  SG  . CYS A 1 528 ? 104.829 118.936 113.684 1.00 91.91 ? 516 CYS A SG  1 
ATOM   3788 N  N   . VAL A 1 529 ? 101.923 121.034 116.969 1.00 92.81 ? 517 VAL A N   1 
ATOM   3789 C  CA  . VAL A 1 529 ? 101.132 121.162 118.190 1.00 92.81 ? 517 VAL A CA  1 
ATOM   3790 C  C   . VAL A 1 529 ? 99.689  121.529 117.881 1.00 92.81 ? 517 VAL A C   1 
ATOM   3791 O  O   . VAL A 1 529 ? 98.765  120.958 118.450 1.00 92.81 ? 517 VAL A O   1 
ATOM   3792 C  CB  . VAL A 1 529 ? 101.746 122.191 119.155 1.00 92.81 ? 517 VAL A CB  1 
ATOM   3793 C  CG1 . VAL A 1 529 ? 100.801 122.504 120.305 1.00 92.81 ? 517 VAL A CG1 1 
ATOM   3794 C  CG2 . VAL A 1 529 ? 103.070 121.679 119.690 1.00 92.81 ? 517 VAL A CG2 1 
ATOM   3795 N  N   . GLY A 1 530 ? 99.487  122.453 116.949 1.00 90.50 ? 518 GLY A N   1 
ATOM   3796 C  CA  . GLY A 1 530 ? 98.143  122.875 116.602 1.00 90.50 ? 518 GLY A CA  1 
ATOM   3797 C  C   . GLY A 1 530 ? 97.293  121.775 116.009 1.00 90.50 ? 518 GLY A C   1 
ATOM   3798 O  O   . GLY A 1 530 ? 96.122  121.639 116.356 1.00 90.50 ? 518 GLY A O   1 
ATOM   3799 N  N   . CYS A 1 531 ? 97.870  120.984 115.115 1.00 88.16 ? 519 CYS A N   1 
ATOM   3800 C  CA  . CYS A 1 531 ? 97.134  119.868 114.540 1.00 88.16 ? 519 CYS A CA  1 
ATOM   3801 C  C   . CYS A 1 531 ? 96.784  118.829 115.596 1.00 88.16 ? 519 CYS A C   1 
ATOM   3802 O  O   . CYS A 1 531 ? 95.675  118.301 115.616 1.00 88.16 ? 519 CYS A O   1 
ATOM   3803 C  CB  . CYS A 1 531 ? 97.912  119.242 113.389 1.00 88.16 ? 519 CYS A CB  1 
ATOM   3804 S  SG  . CYS A 1 531 ? 97.942  120.264 111.902 1.00 88.16 ? 519 CYS A SG  1 
ATOM   3805 N  N   . PHE A 1 532 ? 97.722  118.544 116.488 1.00 88.01 ? 520 PHE A N   1 
ATOM   3806 C  CA  . PHE A 1 532 ? 97.449  117.596 117.552 1.00 88.01 ? 520 PHE A CA  1 
ATOM   3807 C  C   . PHE A 1 532 ? 96.334  118.136 118.432 1.00 88.01 ? 520 PHE A C   1 
ATOM   3808 O  O   . PHE A 1 532 ? 95.444  117.395 118.847 1.00 88.01 ? 520 PHE A O   1 
ATOM   3809 C  CB  . PHE A 1 532 ? 98.710  117.333 118.373 1.00 88.01 ? 520 PHE A CB  1 
ATOM   3810 C  CG  . PHE A 1 532 ? 98.472  116.519 119.609 1.00 88.01 ? 520 PHE A CG  1 
ATOM   3811 C  CD1 . PHE A 1 532 ? 98.160  115.175 119.519 1.00 88.01 ? 520 PHE A CD1 1 
ATOM   3812 C  CD2 . PHE A 1 532 ? 98.567  117.098 120.863 1.00 88.01 ? 520 PHE A CD2 1 
ATOM   3813 C  CE1 . PHE A 1 532 ? 97.941  114.424 120.656 1.00 88.01 ? 520 PHE A CE1 1 
ATOM   3814 C  CE2 . PHE A 1 532 ? 98.348  116.354 122.004 1.00 88.01 ? 520 PHE A CE2 1 
ATOM   3815 C  CZ  . PHE A 1 532 ? 98.036  115.014 121.901 1.00 88.01 ? 520 PHE A CZ  1 
ATOM   3816 N  N   . ILE A 1 533 ? 96.368  119.433 118.711 1.00 90.64 ? 521 ILE A N   1 
ATOM   3817 C  CA  . ILE A 1 533 ? 95.352  120.031 119.566 1.00 90.64 ? 521 ILE A CA  1 
ATOM   3818 C  C   . ILE A 1 533 ? 93.973  119.910 118.924 1.00 90.64 ? 521 ILE A C   1 
ATOM   3819 O  O   . ILE A 1 533 ? 93.007  119.573 119.601 1.00 90.64 ? 521 ILE A O   1 
ATOM   3820 C  CB  . ILE A 1 533 ? 95.701  121.486 119.960 1.00 90.64 ? 521 ILE A CB  1 
ATOM   3821 C  CG1 . ILE A 1 533 ? 97.063  121.538 120.654 1.00 90.64 ? 521 ILE A CG1 1 
ATOM   3822 C  CG2 . ILE A 1 533 ? 94.656  122.088 120.886 1.00 90.64 ? 521 ILE A CG2 1 
ATOM   3823 C  CD1 . ILE A 1 533 ? 97.162  120.702 121.910 1.00 90.64 ? 521 ILE A CD1 1 
ATOM   3824 N  N   . PHE A 1 534 ? 93.887  120.115 117.611 1.00 87.33 ? 522 PHE A N   1 
ATOM   3825 C  CA  . PHE A 1 534 ? 92.603  119.969 116.941 1.00 87.33 ? 522 PHE A CA  1 
ATOM   3826 C  C   . PHE A 1 534 ? 92.098  118.547 117.068 1.00 87.33 ? 522 PHE A C   1 
ATOM   3827 O  O   . PHE A 1 534 ? 90.918  118.340 117.324 1.00 87.33 ? 522 PHE A O   1 
ATOM   3828 C  CB  . PHE A 1 534 ? 92.662  120.340 115.444 1.00 87.33 ? 522 PHE A CB  1 
ATOM   3829 C  CG  . PHE A 1 534 ? 92.995  121.796 115.204 1.00 87.33 ? 522 PHE A CG  1 
ATOM   3830 C  CD1 . PHE A 1 534 ? 92.835  122.744 116.210 1.00 87.33 ? 522 PHE A CD1 1 
ATOM   3831 C  CD2 . PHE A 1 534 ? 93.431  122.222 113.958 1.00 87.33 ? 522 PHE A CD2 1 
ATOM   3832 C  CE1 . PHE A 1 534 ? 93.095  124.077 115.975 1.00 87.33 ? 522 PHE A CE1 1 
ATOM   3833 C  CE2 . PHE A 1 534 ? 93.691  123.553 113.720 1.00 87.33 ? 522 PHE A CE2 1 
ATOM   3834 C  CZ  . PHE A 1 534 ? 93.524  124.479 114.729 1.00 87.33 ? 522 PHE A CZ  1 
ATOM   3835 N  N   . SER A 1 535 ? 92.969  117.556 116.912 1.00 85.09 ? 523 SER A N   1 
ATOM   3836 C  CA  . SER A 1 535 ? 92.476  116.188 116.903 1.00 85.09 ? 523 SER A CA  1 
ATOM   3837 C  C   . SER A 1 535 ? 91.823  115.886 118.230 1.00 85.09 ? 523 SER A C   1 
ATOM   3838 O  O   . SER A 1 535 ? 90.775  115.249 118.278 1.00 85.09 ? 523 SER A O   1 
ATOM   3839 C  CB  . SER A 1 535 ? 93.597  115.200 116.590 1.00 85.09 ? 523 SER A CB  1 
ATOM   3840 O  OG  . SER A 1 535 ? 94.542  115.134 117.641 1.00 85.09 ? 523 SER A OG  1 
ATOM   3841 N  N   . LEU A 1 536 ? 92.435  116.322 119.320 1.00 88.21 ? 524 LEU A N   1 
ATOM   3842 C  CA  . LEU A 1 536 ? 91.784  116.147 120.607 1.00 88.21 ? 524 LEU A CA  1 
ATOM   3843 C  C   . LEU A 1 536 ? 90.504  116.980 120.741 1.00 88.21 ? 524 LEU A C   1 
ATOM   3844 O  O   . LEU A 1 536 ? 89.489  116.479 121.218 1.00 88.21 ? 524 LEU A O   1 
ATOM   3845 C  CB  . LEU A 1 536 ? 92.760  116.453 121.742 1.00 88.21 ? 524 LEU A CB  1 
ATOM   3846 C  CG  . LEU A 1 536 ? 93.527  115.258 122.313 1.00 88.21 ? 524 LEU A CG  1 
ATOM   3847 C  CD1 . LEU A 1 536 ? 92.564  114.283 122.972 1.00 88.21 ? 524 LEU A CD1 1 
ATOM   3848 C  CD2 . LEU A 1 536 ? 94.356  114.552 121.252 1.00 88.21 ? 524 LEU A CD2 1 
ATOM   3849 N  N   . VAL A 1 537 ? 90.544  118.244 120.321 1.00 90.00 ? 525 VAL A N   1 
ATOM   3850 C  CA  . VAL A 1 537 ? 89.376  119.122 120.459 1.00 90.00 ? 525 VAL A CA  1 
ATOM   3851 C  C   . VAL A 1 537 ? 88.175  118.685 119.631 1.00 90.00 ? 525 VAL A C   1 
ATOM   3852 O  O   . VAL A 1 537 ? 87.054  118.620 120.138 1.00 90.00 ? 525 VAL A O   1 
ATOM   3853 C  CB  . VAL A 1 537 ? 89.741  120.585 120.119 1.00 90.00 ? 525 VAL A CB  1 
ATOM   3854 C  CG1 . VAL A 1 537 ? 88.497  121.449 119.975 1.00 90.00 ? 525 VAL A CG1 1 
ATOM   3855 C  CG2 . VAL A 1 537 ? 90.656  121.162 121.188 1.00 90.00 ? 525 VAL A CG2 1 
ATOM   3856 N  N   . LYS A 1 538 ? 88.397  118.442 118.343 1.00 86.42 ? 526 LYS A N   1 
ATOM   3857 C  CA  . LYS A 1 538 ? 87.329  117.986 117.460 1.00 86.42 ? 526 LYS A CA  1 
ATOM   3858 C  C   . LYS A 1 538 ? 87.727  116.589 117.071 1.00 86.42 ? 526 LYS A C   1 
ATOM   3859 O  O   . LYS A 1 538 ? 88.578  116.406 116.203 1.00 86.42 ? 526 LYS A O   1 
ATOM   3860 C  CB  . LYS A 1 538 ? 87.261  118.857 116.210 1.00 86.42 ? 526 LYS A CB  1 
ATOM   3861 C  CG  . LYS A 1 538 ? 87.514  120.330 116.467 1.00 86.42 ? 526 LYS A CG  1 
ATOM   3862 C  CD  . LYS A 1 538 ? 87.529  121.121 115.173 1.00 86.42 ? 526 LYS A CD  1 
ATOM   3863 C  CE  . LYS A 1 538 ? 88.127  122.500 115.392 1.00 86.42 ? 526 LYS A CE  1 
ATOM   3864 N  NZ  . LYS A 1 538 ? 89.534  122.409 115.871 1.00 86.42 ? 526 LYS A NZ  1 
ATOM   3865 N  N   . TYR A 1 539 ? 87.125  115.589 117.697 1.00 87.26 ? 527 TYR A N   1 
ATOM   3866 C  CA  . TYR A 1 539 ? 87.561  114.229 117.435 1.00 87.26 ? 527 TYR A CA  1 
ATOM   3867 C  C   . TYR A 1 539 ? 86.589  113.416 116.613 1.00 87.26 ? 527 TYR A C   1 
ATOM   3868 O  O   . TYR A 1 539 ? 85.422  113.281 116.976 1.00 87.26 ? 527 TYR A O   1 
ATOM   3869 C  CB  . TYR A 1 539 ? 87.836  113.518 118.760 1.00 87.26 ? 527 TYR A CB  1 
ATOM   3870 C  CG  . TYR A 1 539 ? 88.435  112.145 118.609 1.00 87.26 ? 527 TYR A CG  1 
ATOM   3871 C  CD1 . TYR A 1 539 ? 89.779  111.987 118.308 1.00 87.26 ? 527 TYR A CD1 1 
ATOM   3872 C  CD2 . TYR A 1 539 ? 87.661  111.007 118.779 1.00 87.26 ? 527 TYR A CD2 1 
ATOM   3873 C  CE1 . TYR A 1 539 ? 90.334  110.733 118.172 1.00 87.26 ? 527 TYR A CE1 1 
ATOM   3874 C  CE2 . TYR A 1 539 ? 88.207  109.749 118.643 1.00 87.26 ? 527 TYR A CE2 1 
ATOM   3875 C  CZ  . TYR A 1 539 ? 89.543  109.622 118.341 1.00 87.26 ? 527 TYR A CZ  1 
ATOM   3876 O  OH  . TYR A 1 539 ? 90.091  108.376 118.208 1.00 87.26 ? 527 TYR A OH  1 
ATOM   3877 N  N   . VAL A 1 540 ? 87.064  112.872 115.499 1.00 86.16 ? 528 VAL A N   1 
ATOM   3878 C  CA  . VAL A 1 540 ? 86.226  111.999 114.695 1.00 86.16 ? 528 VAL A CA  1 
ATOM   3879 C  C   . VAL A 1 540 ? 86.930  110.650 114.644 1.00 86.16 ? 528 VAL A C   1 
ATOM   3880 O  O   . VAL A 1 540 ? 88.092  110.571 114.248 1.00 86.16 ? 528 VAL A O   1 
ATOM   3881 C  CB  . VAL A 1 540 ? 86.055  112.544 113.264 1.00 86.16 ? 528 VAL A CB  1 
ATOM   3882 C  CG1 . VAL A 1 540 ? 85.109  111.663 112.461 1.00 86.16 ? 528 VAL A CG1 1 
ATOM   3883 C  CG2 . VAL A 1 540 ? 85.548  113.977 113.291 1.00 86.16 ? 528 VAL A CG2 1 
ATOM   3884 N  N   . PRO A 1 541 ? 86.252  109.557 115.091 1.00 89.82 ? 529 PRO A N   1 
ATOM   3885 C  CA  . PRO A 1 541 ? 87.009  108.303 114.978 1.00 89.82 ? 529 PRO A CA  1 
ATOM   3886 C  C   . PRO A 1 541 ? 87.166  107.871 113.527 1.00 89.82 ? 529 PRO A C   1 
ATOM   3887 O  O   . PRO A 1 541 ? 86.320  108.204 112.697 1.00 89.82 ? 529 PRO A O   1 
ATOM   3888 C  CB  . PRO A 1 541 ? 86.144  107.301 115.746 1.00 89.82 ? 529 PRO A CB  1 
ATOM   3889 C  CG  . PRO A 1 541 ? 84.767  107.852 115.675 1.00 89.82 ? 529 PRO A CG  1 
ATOM   3890 C  CD  . PRO A 1 541 ? 84.956  109.333 115.776 1.00 89.82 ? 529 PRO A CD  1 
ATOM   3891 N  N   . LEU A 1 542 ? 88.228  107.135 113.215 1.00 90.92 ? 530 LEU A N   1 
ATOM   3892 C  CA  . LEU A 1 542 ? 88.472  106.755 111.828 1.00 90.92 ? 530 LEU A CA  1 
ATOM   3893 C  C   . LEU A 1 542 ? 87.398  105.828 111.290 1.00 90.92 ? 530 LEU A C   1 
ATOM   3894 O  O   . LEU A 1 542 ? 86.855  105.005 112.023 1.00 90.92 ? 530 LEU A O   1 
ATOM   3895 C  CB  . LEU A 1 542 ? 89.881  106.171 111.641 1.00 90.92 ? 530 LEU A CB  1 
ATOM   3896 C  CG  . LEU A 1 542 ? 90.367  104.899 112.331 1.00 90.92 ? 530 LEU A CG  1 
ATOM   3897 C  CD1 . LEU A 1 542 ? 89.848  103.678 111.589 1.00 90.92 ? 530 LEU A CD1 1 
ATOM   3898 C  CD2 . LEU A 1 542 ? 91.882  104.899 112.289 1.00 90.92 ? 530 LEU A CD2 1 
ATOM   3899 N  N   . THR A 1 543 ? 87.065  105.982 110.015 1.00 90.88 ? 531 THR A N   1 
ATOM   3900 C  CA  . THR A 1 543 ? 86.060  105.136 109.393 1.00 90.88 ? 531 THR A CA  1 
ATOM   3901 C  C   . THR A 1 543 ? 86.656  104.608 108.100 1.00 90.88 ? 531 THR A C   1 
ATOM   3902 O  O   . THR A 1 543 ? 87.523  105.251 107.513 1.00 90.88 ? 531 THR A O   1 
ATOM   3903 C  CB  . THR A 1 543 ? 84.790  105.930 109.049 1.00 90.88 ? 531 THR A CB  1 
ATOM   3904 O  OG1 . THR A 1 543 ? 85.135  107.053 108.229 1.00 90.88 ? 531 THR A OG1 1 
ATOM   3905 C  CG2 . THR A 1 543 ? 84.092  106.422 110.311 1.00 90.88 ? 531 THR A CG2 1 
ATOM   3906 N  N   . TYR A 1 544 ? 86.210  103.433 107.665 1.00 87.96 ? 532 TYR A N   1 
ATOM   3907 C  CA  . TYR A 1 544 ? 86.736  102.839 106.438 1.00 87.96 ? 532 TYR A CA  1 
ATOM   3908 C  C   . TYR A 1 544 ? 85.806  103.067 105.264 1.00 87.96 ? 532 TYR A C   1 
ATOM   3909 O  O   . TYR A 1 544 ? 84.670  102.590 105.286 1.00 87.96 ? 532 TYR A O   1 
ATOM   3910 C  CB  . TYR A 1 544 ? 87.004  101.349 106.624 1.00 87.96 ? 532 TYR A CB  1 
ATOM   3911 C  CG  . TYR A 1 544 ? 87.356  100.641 105.342 1.00 87.96 ? 532 TYR A CG  1 
ATOM   3912 C  CD1 . TYR A 1 544 ? 88.577  100.855 104.726 1.00 87.96 ? 532 TYR A CD1 1 
ATOM   3913 C  CD2 . TYR A 1 544 ? 86.464  99.762  104.746 1.00 87.96 ? 532 TYR A CD2 1 
ATOM   3914 C  CE1 . TYR A 1 544 ? 88.898  100.216 103.548 1.00 87.96 ? 532 TYR A CE1 1 
ATOM   3915 C  CE2 . TYR A 1 544 ? 86.778  99.118  103.570 1.00 87.96 ? 532 TYR A CE2 1 
ATOM   3916 C  CZ  . TYR A 1 544 ? 87.998  99.347  102.977 1.00 87.96 ? 532 TYR A CZ  1 
ATOM   3917 O  OH  . TYR A 1 544 ? 88.316  98.703  101.806 1.00 87.96 ? 532 TYR A OH  1 
ATOM   3918 N  N   . ASN A 1 545 ? 86.253  103.844 104.279 1.00 79.89 ? 533 ASN A N   1 
ATOM   3919 C  CA  . ASN A 1 545 ? 85.459  104.118 103.075 1.00 79.89 ? 533 ASN A CA  1 
ATOM   3920 C  C   . ASN A 1 545 ? 84.215  104.918 103.426 1.00 79.89 ? 533 ASN A C   1 
ATOM   3921 O  O   . ASN A 1 545 ? 83.250  104.905 102.661 1.00 79.89 ? 533 ASN A O   1 
ATOM   3922 C  CB  . ASN A 1 545 ? 85.124  102.835 102.305 1.00 79.89 ? 533 ASN A CB  1 
ATOM   3923 C  CG  . ASN A 1 545 ? 85.041  103.055 100.810 1.00 79.89 ? 533 ASN A CG  1 
ATOM   3924 O  OD1 . ASN A 1 545 ? 85.264  104.161 100.320 1.00 79.89 ? 533 ASN A OD1 1 
ATOM   3925 N  ND2 . ASN A 1 545 ? 84.721  101.999 100.075 1.00 79.89 ? 533 ASN A ND2 1 
ATOM   3926 N  N   . LYS A 1 546 ? 84.211  105.567 104.591 1.00 77.97 ? 534 LYS A N   1 
ATOM   3927 C  CA  . LYS A 1 546 ? 83.089  106.413 105.027 1.00 77.97 ? 534 LYS A CA  1 
ATOM   3928 C  C   . LYS A 1 546 ? 81.838  105.632 105.413 1.00 77.97 ? 534 LYS A C   1 
ATOM   3929 O  O   . LYS A 1 546 ? 80.791  106.226 105.659 1.00 77.97 ? 534 LYS A O   1 
ATOM   3930 C  CB  . LYS A 1 546 ? 82.748  107.514 104.012 1.00 77.97 ? 534 LYS A CB  1 
ATOM   3931 C  CG  . LYS A 1 546 ? 81.642  108.462 104.445 1.00 77.97 ? 534 LYS A CG  1 
ATOM   3932 C  CD  . LYS A 1 546 ? 81.407  109.544 103.403 1.00 77.97 ? 534 LYS A CD  1 
ATOM   3933 C  CE  . LYS A 1 546 ? 80.285  110.483 103.818 1.00 77.97 ? 534 LYS A CE  1 
ATOM   3934 N  NZ  . LYS A 1 546 ? 80.040  111.550 102.809 1.00 77.97 ? 534 LYS A NZ  1 
ATOM   3935 N  N   . THR A 1 547 ? 81.934  104.310 105.464 1.00 85.16 ? 535 THR A N   1 
ATOM   3936 C  CA  . THR A 1 547 ? 80.763  103.503 105.768 1.00 85.16 ? 535 THR A CA  1 
ATOM   3937 C  C   . THR A 1 547 ? 80.903  102.658 107.018 1.00 85.16 ? 535 THR A C   1 
ATOM   3938 O  O   . THR A 1 547 ? 79.905  102.295 107.637 1.00 85.16 ? 535 THR A O   1 
ATOM   3939 C  CB  . THR A 1 547 ? 80.426  102.564 104.597 1.00 85.16 ? 535 THR A CB  1 
ATOM   3940 O  OG1 . THR A 1 547 ? 81.587  101.800 104.251 1.00 85.16 ? 535 THR A OG1 1 
ATOM   3941 C  CG2 . THR A 1 547 ? 79.969  103.358 103.383 1.00 85.16 ? 535 THR A CG2 1 
ATOM   3942 N  N   . TYR A 1 548 ? 82.131  102.343 107.406 1.00 92.20 ? 536 TYR A N   1 
ATOM   3943 C  CA  . TYR A 1 548 ? 82.313  101.450 108.542 1.00 92.20 ? 536 TYR A CA  1 
ATOM   3944 C  C   . TYR A 1 548 ? 82.670  102.202 109.798 1.00 92.20 ? 536 TYR A C   1 
ATOM   3945 O  O   . TYR A 1 548 ? 83.799  102.664 109.940 1.00 92.20 ? 536 TYR A O   1 
ATOM   3946 C  CB  . TYR A 1 548 ? 83.387  100.402 108.249 1.00 92.20 ? 536 TYR A CB  1 
ATOM   3947 C  CG  . TYR A 1 548 ? 83.544  99.374  109.345 1.00 92.20 ? 536 TYR A CG  1 
ATOM   3948 C  CD1 . TYR A 1 548 ? 82.544  98.449  109.599 1.00 92.20 ? 536 TYR A CD1 1 
ATOM   3949 C  CD2 . TYR A 1 548 ? 84.693  99.326  110.122 1.00 92.20 ? 536 TYR A CD2 1 
ATOM   3950 C  CE1 . TYR A 1 548 ? 82.679  97.509  110.600 1.00 92.20 ? 536 TYR A CE1 1 
ATOM   3951 C  CE2 . TYR A 1 548 ? 84.839  98.388  111.124 1.00 92.20 ? 536 TYR A CE2 1 
ATOM   3952 C  CZ  . TYR A 1 548 ? 83.828  97.482  111.358 1.00 92.20 ? 536 TYR A CZ  1 
ATOM   3953 O  OH  . TYR A 1 548 ? 83.961  96.541  112.352 1.00 92.20 ? 536 TYR A OH  1 
ATOM   3954 N  N   . VAL A 1 549 ? 81.722  102.327 110.719 1.00 95.40 ? 537 VAL A N   1 
ATOM   3955 C  CA  . VAL A 1 549 ? 82.044  102.959 111.981 1.00 95.40 ? 537 VAL A CA  1 
ATOM   3956 C  C   . VAL A 1 549 ? 82.892  101.968 112.742 1.00 95.40 ? 537 VAL A C   1 
ATOM   3957 O  O   . VAL A 1 549 ? 82.497  100.817 112.917 1.00 95.40 ? 537 VAL A O   1 
ATOM   3958 C  CB  . VAL A 1 549 ? 80.777  103.264 112.787 1.00 95.40 ? 537 VAL A CB  1 
ATOM   3959 C  CG1 . VAL A 1 549 ? 81.119  104.074 114.028 1.00 95.40 ? 537 VAL A CG1 1 
ATOM   3960 C  CG2 . VAL A 1 549 ? 79.774  104.011 111.923 1.00 95.40 ? 537 VAL A CG2 1 
ATOM   3961 N  N   . TYR A 1 550 ? 84.057  102.400 113.202 1.00 96.51 ? 538 TYR A N   1 
ATOM   3962 C  CA  . TYR A 1 550 ? 84.953  101.469 113.869 1.00 96.51 ? 538 TYR A CA  1 
ATOM   3963 C  C   . TYR A 1 550 ? 84.498  101.105 115.305 1.00 96.51 ? 538 TYR A C   1 
ATOM   3964 O  O   . TYR A 1 550 ? 83.967  101.967 116.005 1.00 96.51 ? 538 TYR A O   1 
ATOM   3965 C  CB  . TYR A 1 550 ? 86.391  101.978 113.856 1.00 96.51 ? 538 TYR A CB  1 
ATOM   3966 C  CG  . TYR A 1 550 ? 87.218  101.479 112.695 1.00 96.51 ? 538 TYR A CG  1 
ATOM   3967 C  CD1 . TYR A 1 550 ? 86.923  101.856 111.395 1.00 96.51 ? 538 TYR A CD1 1 
ATOM   3968 C  CD2 . TYR A 1 550 ? 88.303  100.639 112.901 1.00 96.51 ? 538 TYR A CD2 1 
ATOM   3969 C  CE1 . TYR A 1 550 ? 87.677  101.406 110.333 1.00 96.51 ? 538 TYR A CE1 1 
ATOM   3970 C  CE2 . TYR A 1 550 ? 89.064  100.184 111.843 1.00 96.51 ? 538 TYR A CE2 1 
ATOM   3971 C  CZ  . TYR A 1 550 ? 88.744  100.572 110.562 1.00 96.51 ? 538 TYR A CZ  1 
ATOM   3972 O  OH  . TYR A 1 550 ? 89.492  100.131 109.500 1.00 96.51 ? 538 TYR A OH  1 
ATOM   3973 N  N   . PRO A 1 551 ? 84.696  99.832  115.752 1.00 97.07 ? 539 PRO A N   1 
ATOM   3974 C  CA  . PRO A 1 551 ? 84.259  99.547  117.119 1.00 97.07 ? 539 PRO A CA  1 
ATOM   3975 C  C   . PRO A 1 551 ? 85.076  100.346 118.115 1.00 97.07 ? 539 PRO A C   1 
ATOM   3976 O  O   . PRO A 1 551 ? 86.243  100.623 117.864 1.00 97.07 ? 539 PRO A O   1 
ATOM   3977 C  CB  . PRO A 1 551 ? 84.564  98.060  117.274 1.00 97.07 ? 539 PRO A CB  1 
ATOM   3978 C  CG  . PRO A 1 551 ? 84.549  97.522  115.890 1.00 97.07 ? 539 PRO A CG  1 
ATOM   3979 C  CD  . PRO A 1 551 ? 85.120  98.615  115.044 1.00 97.07 ? 539 PRO A CD  1 
ATOM   3980 N  N   . ASN A 1 552 ? 84.470  100.731 119.230 1.00 96.75 ? 540 ASN A N   1 
ATOM   3981 C  CA  . ASN A 1 552 ? 85.178  101.522 120.229 1.00 96.75 ? 540 ASN A CA  1 
ATOM   3982 C  C   . ASN A 1 552 ? 86.515  100.893 120.592 1.00 96.75 ? 540 ASN A C   1 
ATOM   3983 O  O   . ASN A 1 552 ? 87.518  101.592 120.717 1.00 96.75 ? 540 ASN A O   1 
ATOM   3984 C  CB  . ASN A 1 552 ? 84.314  101.755 121.475 1.00 96.75 ? 540 ASN A CB  1 
ATOM   3985 C  CG  . ASN A 1 552 ? 83.806  100.466 122.104 1.00 96.75 ? 540 ASN A CG  1 
ATOM   3986 O  OD1 . ASN A 1 552 ? 83.760  99.413  121.467 1.00 96.75 ? 540 ASN A OD1 1 
ATOM   3987 N  ND2 . ASN A 1 552 ? 83.409  100.552 123.368 1.00 96.75 ? 540 ASN A ND2 1 
ATOM   3988 N  N   . TRP A 1 553 ? 86.538  99.574  120.744 1.00 97.43 ? 541 TRP A N   1 
ATOM   3989 C  CA  . TRP A 1 553 ? 87.773  98.890  121.109 1.00 97.43 ? 541 TRP A CA  1 
ATOM   3990 C  C   . TRP A 1 553 ? 88.842  99.041  120.040 1.00 97.43 ? 541 TRP A C   1 
ATOM   3991 O  O   . TRP A 1 553 ? 90.007  99.203  120.362 1.00 97.43 ? 541 TRP A O   1 
ATOM   3992 C  CB  . TRP A 1 553 ? 87.534  97.410  121.456 1.00 97.43 ? 541 TRP A CB  1 
ATOM   3993 C  CG  . TRP A 1 553 ? 87.094  96.533  120.317 1.00 97.43 ? 541 TRP A CG  1 
ATOM   3994 C  CD1 . TRP A 1 553 ? 85.813  96.248  119.952 1.00 97.43 ? 541 TRP A CD1 1 
ATOM   3995 C  CD2 . TRP A 1 553 ? 87.939  95.807  119.412 1.00 97.43 ? 541 TRP A CD2 1 
ATOM   3996 N  NE1 . TRP A 1 553 ? 85.806  95.402  118.869 1.00 97.43 ? 541 TRP A NE1 1 
ATOM   3997 C  CE2 . TRP A 1 553 ? 87.099  95.120  118.517 1.00 97.43 ? 541 TRP A CE2 1 
ATOM   3998 C  CE3 . TRP A 1 553 ? 89.325  95.680  119.267 1.00 97.43 ? 541 TRP A CE3 1 
ATOM   3999 C  CZ2 . TRP A 1 553 ? 87.596  94.316  117.495 1.00 97.43 ? 541 TRP A CZ2 1 
ATOM   4000 C  CZ3 . TRP A 1 553 ? 89.815  94.887  118.251 1.00 97.43 ? 541 TRP A CZ3 1 
ATOM   4001 C  CH2 . TRP A 1 553 ? 88.953  94.213  117.379 1.00 97.43 ? 541 TRP A CH2 1 
ATOM   4002 N  N   . ALA A 1 554 ? 88.451  98.962  118.771 1.00 97.59 ? 542 ALA A N   1 
ATOM   4003 C  CA  . ALA A 1 554 ? 89.407  99.082  117.677 1.00 97.59 ? 542 ALA A CA  1 
ATOM   4004 C  C   . ALA A 1 554 ? 90.037  100.454 117.651 1.00 97.59 ? 542 ALA A C   1 
ATOM   4005 O  O   . ALA A 1 554 ? 91.233  100.581 117.421 1.00 97.59 ? 542 ALA A O   1 
ATOM   4006 C  CB  . ALA A 1 554 ? 88.733  98.782  116.353 1.00 97.59 ? 542 ALA A CB  1 
ATOM   4007 N  N   . ILE A 1 555 ? 89.235  101.488 117.876 1.00 96.71 ? 543 ILE A N   1 
ATOM   4008 C  CA  . ILE A 1 555 ? 89.774  102.841 117.932 1.00 96.71 ? 543 ILE A CA  1 
ATOM   4009 C  C   . ILE A 1 555 ? 90.730  102.942 119.109 1.00 96.71 ? 543 ILE A C   1 
ATOM   4010 O  O   . ILE A 1 555 ? 91.807  103.523 118.992 1.00 96.71 ? 543 ILE A O   1 
ATOM   4011 C  CB  . ILE A 1 555 ? 88.646  103.880 118.035 1.00 96.71 ? 543 ILE A CB  1 
ATOM   4012 C  CG1 . ILE A 1 555 ? 87.891  103.951 116.712 1.00 96.71 ? 543 ILE A CG1 1 
ATOM   4013 C  CG2 . ILE A 1 555 ? 89.195  105.254 118.370 1.00 96.71 ? 543 ILE A CG2 1 
ATOM   4014 C  CD1 . ILE A 1 555 ? 88.775  104.337 115.548 1.00 96.71 ? 543 ILE A CD1 1 
ATOM   4015 N  N   . GLY A 1 556 ? 90.357  102.348 120.238 1.00 96.87 ? 544 GLY A N   1 
ATOM   4016 C  CA  . GLY A 1 556 ? 91.237  102.342 121.391 1.00 96.87 ? 544 GLY A CA  1 
ATOM   4017 C  C   . GLY A 1 556 ? 92.502  101.582 121.079 1.00 96.87 ? 544 GLY A C   1 
ATOM   4018 O  O   . GLY A 1 556 ? 93.581  102.004 121.471 1.00 96.87 ? 544 GLY A O   1 
ATOM   4019 N  N   . LEU A 1 557 ? 92.388  100.462 120.377 1.00 96.52 ? 545 LEU A N   1 
ATOM   4020 C  CA  . LEU A 1 557 ? 93.563  99.678  120.014 1.00 96.52 ? 545 LEU A CA  1 
ATOM   4021 C  C   . LEU A 1 557 ? 94.477  100.513 119.142 1.00 96.52 ? 545 LEU A C   1 
ATOM   4022 O  O   . LEU A 1 557 ? 95.698  100.469 119.280 1.00 96.52 ? 545 LEU A O   1 
ATOM   4023 C  CB  . LEU A 1 557 ? 93.159  98.402  119.277 1.00 96.52 ? 545 LEU A CB  1 
ATOM   4024 C  CG  . LEU A 1 557 ? 94.271  97.450  118.839 1.00 96.52 ? 545 LEU A CG  1 
ATOM   4025 C  CD1 . LEU A 1 557 ? 95.048  96.941  120.043 1.00 96.52 ? 545 LEU A CD1 1 
ATOM   4026 C  CD2 . LEU A 1 557 ? 93.690  96.292  118.045 1.00 96.52 ? 545 LEU A CD2 1 
ATOM   4027 N  N   . GLY A 1 558 ? 93.887  101.283 118.239 1.00 96.36 ? 546 GLY A N   1 
ATOM   4028 C  CA  . GLY A 1 558 ? 94.682  102.127 117.374 1.00 96.36 ? 546 GLY A CA  1 
ATOM   4029 C  C   . GLY A 1 558 ? 95.445  103.172 118.144 1.00 96.36 ? 546 GLY A C   1 
ATOM   4030 O  O   . GLY A 1 558 ? 96.614  103.422 117.876 1.00 96.36 ? 546 GLY A O   1 
ATOM   4031 N  N   . TRP A 1 559 ? 94.787  103.809 119.103 1.00 95.94 ? 547 TRP A N   1 
ATOM   4032 C  CA  . TRP A 1 559 ? 95.478  104.788 119.923 1.00 95.94 ? 547 TRP A CA  1 
ATOM   4033 C  C   . TRP A 1 559 ? 96.595  104.120 120.681 1.00 95.94 ? 547 TRP A C   1 
ATOM   4034 O  O   . TRP A 1 559 ? 97.589  104.757 120.989 1.00 95.94 ? 547 TRP A O   1 
ATOM   4035 C  CB  . TRP A 1 559 ? 94.531  105.504 120.875 1.00 95.94 ? 547 TRP A CB  1 
ATOM   4036 C  CG  . TRP A 1 559 ? 93.985  106.758 120.297 1.00 95.94 ? 547 TRP A CG  1 
ATOM   4037 C  CD1 . TRP A 1 559 ? 92.705  106.983 119.892 1.00 95.94 ? 547 TRP A CD1 1 
ATOM   4038 C  CD2 . TRP A 1 559 ? 94.707  107.968 120.039 1.00 95.94 ? 547 TRP A CD2 1 
ATOM   4039 N  NE1 . TRP A 1 559 ? 92.582  108.260 119.406 1.00 95.94 ? 547 TRP A NE1 1 
ATOM   4040 C  CE2 . TRP A 1 559 ? 93.797  108.886 119.484 1.00 95.94 ? 547 TRP A CE2 1 
ATOM   4041 C  CE3 . TRP A 1 559 ? 96.035  108.365 120.228 1.00 95.94 ? 547 TRP A CE3 1 
ATOM   4042 C  CZ2 . TRP A 1 559 ? 94.169  110.175 119.115 1.00 95.94 ? 547 TRP A CZ2 1 
ATOM   4043 C  CZ3 . TRP A 1 559 ? 96.402  109.643 119.861 1.00 95.94 ? 547 TRP A CZ3 1 
ATOM   4044 C  CH2 . TRP A 1 559 ? 95.473  110.534 119.313 1.00 95.94 ? 547 TRP A CH2 1 
ATOM   4045 N  N   . SER A 1 560 ? 96.448  102.834 120.977 1.00 97.69 ? 548 SER A N   1 
ATOM   4046 C  CA  . SER A 1 560 ? 97.514  102.107 121.651 1.00 97.69 ? 548 SER A CA  1 
ATOM   4047 C  C   . SER A 1 560 ? 98.693  101.974 120.715 1.00 97.69 ? 548 SER A C   1 
ATOM   4048 O  O   . SER A 1 560 ? 99.824  101.956 121.167 1.00 97.69 ? 548 SER A O   1 
ATOM   4049 C  CB  . SER A 1 560 ? 97.041  100.734 122.112 1.00 97.69 ? 548 SER A CB  1 
ATOM   4050 O  OG  . SER A 1 560 ? 95.854  100.840 122.875 1.00 97.69 ? 548 SER A OG  1 
ATOM   4051 N  N   . LEU A 1 561 ? 98.442  101.815 119.419 1.00 96.84 ? 549 LEU A N   1 
ATOM   4052 C  CA  . LEU A 1 561 ? 99.539  101.793 118.449 1.00 96.84 ? 549 LEU A CA  1 
ATOM   4053 C  C   . LEU A 1 561 ? 100.228 103.145 118.374 1.00 96.84 ? 549 LEU A C   1 
ATOM   4054 O  O   . LEU A 1 561 ? 101.452 103.216 118.301 1.00 96.84 ? 549 LEU A O   1 
ATOM   4055 C  CB  . LEU A 1 561 ? 99.038  101.403 117.061 1.00 96.84 ? 549 LEU A CB  1 
ATOM   4056 C  CG  . LEU A 1 561 ? 98.438  100.013 116.878 1.00 96.84 ? 549 LEU A CG  1 
ATOM   4057 C  CD1 . LEU A 1 561 ? 97.908  99.894  115.462 1.00 96.84 ? 549 LEU A CD1 1 
ATOM   4058 C  CD2 . LEU A 1 561 ? 99.482  98.943  117.151 1.00 96.84 ? 549 LEU A CD2 1 
ATOM   4059 N  N   . ALA A 1 562 ? 99.456  104.222 118.388 1.00 96.07 ? 550 ALA A N   1 
ATOM   4060 C  CA  . ALA A 1 562 ? 100.036 105.557 118.322 1.00 96.07 ? 550 ALA A CA  1 
ATOM   4061 C  C   . ALA A 1 562 ? 100.690 105.917 119.634 1.00 96.07 ? 550 ALA A C   1 
ATOM   4062 O  O   . ALA A 1 562 ? 101.800 106.432 119.651 1.00 96.07 ? 550 ALA A O   1 
ATOM   4063 C  CB  . ALA A 1 562 ? 98.972  106.580 117.975 1.00 96.07 ? 550 ALA A CB  1 
ATOM   4064 N  N   . LEU A 1 563 ? 100.017 105.631 120.738 1.00 97.20 ? 551 LEU A N   1 
ATOM   4065 C  CA  . LEU A 1 563 ? 100.537 106.015 122.044 1.00 97.20 ? 551 LEU A CA  1 
ATOM   4066 C  C   . LEU A 1 563 ? 101.849 105.350 122.370 1.00 97.20 ? 551 LEU A C   1 
ATOM   4067 O  O   . LEU A 1 563 ? 102.702 105.977 122.954 1.00 97.20 ? 551 LEU A O   1 
ATOM   4068 C  CB  . LEU A 1 563 ? 99.528  105.758 123.164 1.00 97.20 ? 551 LEU A CB  1 
ATOM   4069 C  CG  . LEU A 1 563 ? 99.776  106.471 124.491 1.00 97.20 ? 551 LEU A CG  1 
ATOM   4070 C  CD1 . LEU A 1 563 ? 99.800  107.976 124.281 1.00 97.20 ? 551 LEU A CD1 1 
ATOM   4071 C  CD2 . LEU A 1 563 ? 98.709  106.087 125.503 1.00 97.20 ? 551 LEU A CD2 1 
ATOM   4072 N  N   . SER A 1 564 ? 102.039 104.092 121.995 1.00 97.73 ? 552 SER A N   1 
ATOM   4073 C  CA  . SER A 1 564 ? 103.263 103.416 122.409 1.00 97.73 ? 552 SER A CA  1 
ATOM   4074 C  C   . SER A 1 564 ? 104.482 104.149 121.882 1.00 97.73 ? 552 SER A C   1 
ATOM   4075 O  O   . SER A 1 564 ? 105.440 104.359 122.620 1.00 97.73 ? 552 SER A O   1 
ATOM   4076 C  CB  . SER A 1 564 ? 103.265 101.976 121.906 1.00 97.73 ? 552 SER A CB  1 
ATOM   4077 O  OG  . SER A 1 564 ? 103.009 101.922 120.514 1.00 97.73 ? 552 SER A OG  1 
ATOM   4078 N  N   . SER A 1 565 ? 104.461 104.550 120.618 1.00 97.69 ? 553 SER A N   1 
ATOM   4079 C  CA  . SER A 1 565 ? 105.557 105.348 120.082 1.00 97.69 ? 553 SER A CA  1 
ATOM   4080 C  C   . SER A 1 565 ? 105.634 106.733 120.706 1.00 97.69 ? 553 SER A C   1 
ATOM   4081 O  O   . SER A 1 565 ? 106.714 107.197 121.055 1.00 97.69 ? 553 SER A O   1 
ATOM   4082 C  CB  . SER A 1 565 ? 105.398 105.476 118.579 1.00 97.69 ? 553 SER A CB  1 
ATOM   4083 O  OG  . SER A 1 565 ? 104.099 105.917 118.238 1.00 97.69 ? 553 SER A OG  1 
ATOM   4084 N  N   . MET A 1 566 ? 104.488 107.392 120.861 1.00 96.90 ? 554 MET A N   1 
ATOM   4085 C  CA  . MET A 1 566 ? 104.455 108.730 121.448 1.00 96.90 ? 554 MET A CA  1 
ATOM   4086 C  C   . MET A 1 566 ? 104.923 108.692 122.882 1.00 96.90 ? 554 MET A C   1 
ATOM   4087 O  O   . MET A 1 566 ? 105.648 109.574 123.311 1.00 96.90 ? 554 MET A O   1 
ATOM   4088 C  CB  . MET A 1 566 ? 103.038 109.293 121.409 1.00 96.90 ? 554 MET A CB  1 
ATOM   4089 C  CG  . MET A 1 566 ? 102.544 109.688 120.034 1.00 96.90 ? 554 MET A CG  1 
ATOM   4090 S  SD  . MET A 1 566 ? 100.748 109.810 119.994 1.00 96.90 ? 554 MET A SD  1 
ATOM   4091 C  CE  . MET A 1 566 ? 100.435 110.866 121.403 1.00 96.90 ? 554 MET A CE  1 
ATOM   4092 N  N   . LEU A 1 567 ? 104.518 107.670 123.621 1.00 98.00 ? 555 LEU A N   1 
ATOM   4093 C  CA  . LEU A 1 567 ? 104.870 107.542 125.030 1.00 98.00 ? 555 LEU A CA  1 
ATOM   4094 C  C   . LEU A 1 567 ? 106.352 107.367 125.261 1.00 98.00 ? 555 LEU A C   1 
ATOM   4095 O  O   . LEU A 1 567 ? 106.849 107.712 126.326 1.00 98.00 ? 555 LEU A O   1 
ATOM   4096 C  CB  . LEU A 1 567 ? 104.119 106.370 125.661 1.00 98.00 ? 555 LEU A CB  1 
ATOM   4097 C  CG  . LEU A 1 567 ? 104.215 106.192 127.174 1.00 98.00 ? 555 LEU A CG  1 
ATOM   4098 C  CD1 . LEU A 1 567 ? 104.528 107.523 127.841 1.00 98.00 ? 555 LEU A CD1 1 
ATOM   4099 C  CD2 . LEU A 1 567 ? 102.912 105.618 127.707 1.00 98.00 ? 555 LEU A CD2 1 
ATOM   4100 N  N   . CYS A 1 568 ? 107.057 106.816 124.279 1.00 98.48 ? 556 CYS A N   1 
ATOM   4101 C  CA  . CYS A 1 568 ? 108.483 106.561 124.441 1.00 98.48 ? 556 CYS A CA  1 
ATOM   4102 C  C   . CYS A 1 568 ? 109.222 107.805 124.878 1.00 98.48 ? 556 CYS A C   1 
ATOM   4103 O  O   . CYS A 1 568 ? 109.994 107.759 125.824 1.00 98.48 ? 556 CYS A O   1 
ATOM   4104 C  CB  . CYS A 1 568 ? 109.103 106.021 123.156 1.00 98.48 ? 556 CYS A CB  1 
ATOM   4105 S  SG  . CYS A 1 568 ? 108.759 104.282 122.819 1.00 98.48 ? 556 CYS A SG  1 
ATOM   4106 N  N   . VAL A 1 569 ? 108.994 108.924 124.199 1.00 98.25 ? 557 VAL A N   1 
ATOM   4107 C  CA  . VAL A 1 569 ? 109.758 110.125 124.529 1.00 98.25 ? 557 VAL A CA  1 
ATOM   4108 C  C   . VAL A 1 569 ? 109.534 110.647 125.952 1.00 98.25 ? 557 VAL A C   1 
ATOM   4109 O  O   . VAL A 1 569 ? 110.501 110.932 126.644 1.00 98.25 ? 557 VAL A O   1 
ATOM   4110 C  CB  . VAL A 1 569 ? 109.556 111.252 123.494 1.00 98.25 ? 557 VAL A CB  1 
ATOM   4111 C  CG1 . VAL A 1 569 ? 110.274 112.507 123.959 1.00 98.25 ? 557 VAL A CG1 1 
ATOM   4112 C  CG2 . VAL A 1 569 ? 110.075 110.818 122.134 1.00 98.25 ? 557 VAL A CG2 1 
ATOM   4113 N  N   . PRO A 1 570 ? 108.272 110.729 126.420 1.00 98.15 ? 558 PRO A N   1 
ATOM   4114 C  CA  . PRO A 1 570 ? 108.121 111.136 127.819 1.00 98.15 ? 558 PRO A CA  1 
ATOM   4115 C  C   . PRO A 1 570 ? 108.642 110.077 128.762 1.00 98.15 ? 558 PRO A C   1 
ATOM   4116 O  O   . PRO A 1 570 ? 109.247 110.418 129.770 1.00 98.15 ? 558 PRO A O   1 
ATOM   4117 C  CB  . PRO A 1 570 ? 106.611 111.239 127.983 1.00 98.15 ? 558 PRO A CB  1 
ATOM   4118 C  CG  . PRO A 1 570 ? 106.137 111.662 126.647 1.00 98.15 ? 558 PRO A CG  1 
ATOM   4119 C  CD  . PRO A 1 570 ? 107.014 110.930 125.677 1.00 98.15 ? 558 PRO A CD  1 
ATOM   4120 N  N   . LEU A 1 571 ? 108.416 108.809 128.445 1.00 98.18 ? 559 LEU A N   1 
ATOM   4121 C  CA  . LEU A 1 571 ? 108.816 107.739 129.350 1.00 98.18 ? 559 LEU A CA  1 
ATOM   4122 C  C   . LEU A 1 571 ? 110.323 107.681 129.511 1.00 98.18 ? 559 LEU A C   1 
ATOM   4123 O  O   . LEU A 1 571 ? 110.816 107.534 130.618 1.00 98.18 ? 559 LEU A O   1 
ATOM   4124 C  CB  . LEU A 1 571 ? 108.301 106.391 128.854 1.00 98.18 ? 559 LEU A CB  1 
ATOM   4125 C  CG  . LEU A 1 571 ? 108.421 105.204 129.806 1.00 98.18 ? 559 LEU A CG  1 
ATOM   4126 C  CD1 . LEU A 1 571 ? 107.673 105.488 131.099 1.00 98.18 ? 559 LEU A CD1 1 
ATOM   4127 C  CD2 . LEU A 1 571 ? 107.888 103.946 129.139 1.00 98.18 ? 559 LEU A CD2 1 
ATOM   4128 N  N   . VAL A 1 572 ? 111.057 107.827 128.415 1.00 98.08 ? 560 VAL A N   1 
ATOM   4129 C  CA  . VAL A 1 572 ? 112.509 107.799 128.492 1.00 98.08 ? 560 VAL A CA  1 
ATOM   4130 C  C   . VAL A 1 572 ? 112.996 109.015 129.264 1.00 98.08 ? 560 VAL A C   1 
ATOM   4131 O  O   . VAL A 1 572 ? 113.909 108.899 130.069 1.00 98.08 ? 560 VAL A O   1 
ATOM   4132 C  CB  . VAL A 1 572 ? 113.173 107.691 127.104 1.00 98.08 ? 560 VAL A CB  1 
ATOM   4133 C  CG1 . VAL A 1 572 ? 114.677 107.892 127.198 1.00 98.08 ? 560 VAL A CG1 1 
ATOM   4134 C  CG2 . VAL A 1 572 ? 112.870 106.337 126.484 1.00 98.08 ? 560 VAL A CG2 1 
ATOM   4135 N  N   . ILE A 1 573 ? 112.375 110.175 129.053 1.00 98.12 ? 561 ILE A N   1 
ATOM   4136 C  CA  . ILE A 1 573 ? 112.753 111.348 129.839 1.00 98.12 ? 561 ILE A CA  1 
ATOM   4137 C  C   . ILE A 1 573 ? 112.671 110.986 131.315 1.00 98.12 ? 561 ILE A C   1 
ATOM   4138 O  O   . ILE A 1 573 ? 113.616 111.211 132.067 1.00 98.12 ? 561 ILE A O   1 
ATOM   4139 C  CB  . ILE A 1 573 ? 111.855 112.558 129.534 1.00 98.12 ? 561 ILE A CB  1 
ATOM   4140 C  CG1 . ILE A 1 573 ? 112.156 113.100 128.138 1.00 98.12 ? 561 ILE A CG1 1 
ATOM   4141 C  CG2 . ILE A 1 573 ? 112.062 113.663 130.557 1.00 98.12 ? 561 ILE A CG2 1 
ATOM   4142 C  CD1 . ILE A 1 573 ? 111.200 114.185 127.698 1.00 98.12 ? 561 ILE A CD1 1 
ATOM   4143 N  N   . VAL A 1 574 ? 111.549 110.406 131.729 1.00 97.93 ? 562 VAL A N   1 
ATOM   4144 C  CA  . VAL A 1 574 ? 111.383 110.012 133.125 1.00 97.93 ? 562 VAL A CA  1 
ATOM   4145 C  C   . VAL A 1 574 ? 112.385 108.946 133.534 1.00 97.93 ? 562 VAL A C   1 
ATOM   4146 O  O   . VAL A 1 574 ? 112.993 109.042 134.590 1.00 97.93 ? 562 VAL A O   1 
ATOM   4147 C  CB  . VAL A 1 574 ? 109.960 109.477 133.385 1.00 97.93 ? 562 VAL A CB  1 
ATOM   4148 C  CG1 . VAL A 1 574 ? 109.803 109.013 134.825 1.00 97.93 ? 562 VAL A CG1 1 
ATOM   4149 C  CG2 . VAL A 1 574 ? 108.927 110.543 133.057 1.00 97.93 ? 562 VAL A CG2 1 
ATOM   4150 N  N   . ILE A 1 575 ? 112.589 107.949 132.683 1.00 97.47 ? 563 ILE A N   1 
ATOM   4151 C  CA  . ILE A 1 575 ? 113.504 106.868 133.018 1.00 97.47 ? 563 ILE A CA  1 
ATOM   4152 C  C   . ILE A 1 575 ? 114.917 107.401 133.173 1.00 97.47 ? 563 ILE A C   1 
ATOM   4153 O  O   . ILE A 1 575 ? 115.605 107.075 134.131 1.00 97.47 ? 563 ILE A O   1 
ATOM   4154 C  CB  . ILE A 1 575 ? 113.477 105.747 131.957 1.00 97.47 ? 563 ILE A CB  1 
ATOM   4155 C  CG1 . ILE A 1 575 ? 112.163 104.970 132.042 1.00 97.47 ? 563 ILE A CG1 1 
ATOM   4156 C  CG2 . ILE A 1 575 ? 114.639 104.784 132.139 1.00 97.47 ? 563 ILE A CG2 1 
ATOM   4157 C  CD1 . ILE A 1 575 ? 111.974 103.969 130.924 1.00 97.47 ? 563 ILE A CD1 1 
ATOM   4158 N  N   . ARG A 1 576 ? 115.365 108.216 132.226 1.00 94.84 ? 564 ARG A N   1 
ATOM   4159 C  CA  . ARG A 1 576 ? 116.706 108.784 132.304 1.00 94.84 ? 564 ARG A CA  1 
ATOM   4160 C  C   . ARG A 1 576 ? 116.852 109.548 133.598 1.00 94.84 ? 564 ARG A C   1 
ATOM   4161 O  O   . ARG A 1 576 ? 117.792 109.322 134.350 1.00 94.84 ? 564 ARG A O   1 
ATOM   4162 C  CB  . ARG A 1 576 ? 116.977 109.721 131.128 1.00 94.84 ? 564 ARG A CB  1 
ATOM   4163 C  CG  . ARG A 1 576 ? 117.317 109.031 129.819 1.00 94.84 ? 564 ARG A CG  1 
ATOM   4164 C  CD  . ARG A 1 576 ? 118.640 108.293 129.919 1.00 94.84 ? 564 ARG A CD  1 
ATOM   4165 N  NE  . ARG A 1 576 ? 119.262 108.107 128.612 1.00 94.84 ? 564 ARG A NE  1 
ATOM   4166 C  CZ  . ARG A 1 576 ? 120.137 108.953 128.078 1.00 94.84 ? 564 ARG A CZ  1 
ATOM   4167 N  NH1 . ARG A 1 576 ? 120.494 110.044 128.740 1.00 94.84 ? 564 ARG A NH1 1 
ATOM   4168 N  NH2 . ARG A 1 576 ? 120.657 108.710 126.882 1.00 94.84 ? 564 ARG A NH2 1 
ATOM   4169 N  N   . LEU A 1 577 ? 115.938 110.469 133.866 1.00 96.07 ? 565 LEU A N   1 
ATOM   4170 C  CA  . LEU A 1 577 ? 116.073 111.297 135.058 1.00 96.07 ? 565 LEU A CA  1 
ATOM   4171 C  C   . LEU A 1 577 ? 116.232 110.432 136.300 1.00 96.07 ? 565 LEU A C   1 
ATOM   4172 O  O   . LEU A 1 577 ? 117.068 110.718 137.155 1.00 96.07 ? 565 LEU A O   1 
ATOM   4173 C  CB  . LEU A 1 577 ? 114.882 112.242 135.200 1.00 96.07 ? 565 LEU A CB  1 
ATOM   4174 C  CG  . LEU A 1 577 ? 115.200 113.539 135.943 1.00 96.07 ? 565 LEU A CG  1 
ATOM   4175 C  CD1 . LEU A 1 577 ? 116.419 114.205 135.325 1.00 96.07 ? 565 LEU A CD1 1 
ATOM   4176 C  CD2 . LEU A 1 577 ? 114.004 114.478 135.927 1.00 96.07 ? 565 LEU A CD2 1 
ATOM   4177 N  N   . CYS A 1 578 ? 115.442 109.367 136.397 1.00 95.59 ? 566 CYS A N   1 
ATOM   4178 C  CA  . CYS A 1 578 ? 115.513 108.487 137.560 1.00 95.59 ? 566 CYS A CA  1 
ATOM   4179 C  C   . CYS A 1 578 ? 116.862 107.789 137.699 1.00 95.59 ? 566 CYS A C   1 
ATOM   4180 O  O   . CYS A 1 578 ? 117.404 107.695 138.798 1.00 95.59 ? 566 CYS A O   1 
ATOM   4181 C  CB  . CYS A 1 578 ? 114.392 107.449 137.506 1.00 95.59 ? 566 CYS A CB  1 
ATOM   4182 S  SG  . CYS A 1 578 ? 114.277 106.387 138.964 1.00 95.59 ? 566 CYS A SG  1 
ATOM   4183 N  N   . GLN A 1 579 ? 117.400 107.287 136.593 1.00 93.20 ? 567 GLN A N   1 
ATOM   4184 C  CA  . GLN A 1 579 ? 118.674 106.571 136.641 1.00 93.20 ? 567 GLN A CA  1 
ATOM   4185 C  C   . GLN A 1 579 ? 119.806 107.494 137.051 1.00 93.20 ? 567 GLN A C   1 
ATOM   4186 O  O   . GLN A 1 579 ? 120.691 107.100 137.808 1.00 93.20 ? 567 GLN A O   1 
ATOM   4187 C  CB  . GLN A 1 579 ? 118.990 105.927 135.291 1.00 93.20 ? 567 GLN A CB  1 
ATOM   4188 C  CG  . GLN A 1 579 ? 117.928 104.961 134.790 1.00 93.20 ? 567 GLN A CG  1 
ATOM   4189 C  CD  . GLN A 1 579 ? 117.700 103.787 135.723 1.00 93.20 ? 567 GLN A CD  1 
ATOM   4190 O  OE1 . GLN A 1 579 ? 118.636 103.269 136.334 1.00 93.20 ? 567 GLN A OE1 1 
ATOM   4191 N  NE2 . GLN A 1 579 ? 116.451 103.348 135.822 1.00 93.20 ? 567 GLN A NE2 1 
ATOM   4192 N  N   . THR A 1 580 ? 119.783 108.723 136.553 1.00 92.37 ? 568 THR A N   1 
ATOM   4193 C  CA  . THR A 1 580 ? 120.813 109.690 136.908 1.00 92.37 ? 568 THR A CA  1 
ATOM   4194 C  C   . THR A 1 580 ? 120.682 110.035 138.383 1.00 92.37 ? 568 THR A C   1 
ATOM   4195 O  O   . THR A 1 580 ? 119.577 110.060 138.922 1.00 92.37 ? 568 THR A O   1 
ATOM   4196 C  CB  . THR A 1 580 ? 120.684 110.966 136.061 1.00 92.37 ? 568 THR A CB  1 
ATOM   4197 O  OG1 . THR A 1 580 ? 120.330 110.609 134.720 1.00 92.37 ? 568 THR A OG1 1 
ATOM   4198 C  CG2 . THR A 1 580 ? 121.993 111.744 136.044 1.00 92.37 ? 568 THR A CG2 1 
ATOM   4199 N  N   . GLU A 1 581 ? 121.805 110.282 139.048 1.00 88.82 ? 569 GLU A N   1 
ATOM   4200 C  CA  . GLU A 1 581 ? 121.773 110.595 140.472 1.00 88.82 ? 569 GLU A CA  1 
ATOM   4201 C  C   . GLU A 1 581 ? 122.159 112.040 140.751 1.00 88.82 ? 569 GLU A C   1 
ATOM   4202 O  O   . GLU A 1 581 ? 123.095 112.560 140.145 1.00 88.82 ? 569 GLU A O   1 
ATOM   4203 C  CB  . GLU A 1 581 ? 122.699 109.654 141.242 1.00 88.82 ? 569 GLU A CB  1 
ATOM   4204 C  CG  . GLU A 1 581 ? 122.358 108.182 141.082 1.00 88.82 ? 569 GLU A CG  1 
ATOM   4205 C  CD  . GLU A 1 581 ? 123.324 107.277 141.818 1.00 88.82 ? 569 GLU A CD  1 
ATOM   4206 O  OE1 . GLU A 1 581 ? 124.244 107.802 142.479 1.00 88.82 ? 569 GLU A OE1 1 
ATOM   4207 O  OE2 . GLU A 1 581 ? 123.165 106.041 141.736 1.00 88.82 ? 569 GLU A OE2 1 
ATOM   4208 N  N   . GLY A 1 582 ? 121.440 112.693 141.661 1.00 90.94 ? 570 GLY A N   1 
ATOM   4209 C  CA  . GLY A 1 582 ? 121.770 114.060 142.026 1.00 90.94 ? 570 GLY A CA  1 
ATOM   4210 C  C   . GLY A 1 582 ? 120.529 114.906 142.206 1.00 90.94 ? 570 GLY A C   1 
ATOM   4211 O  O   . GLY A 1 582 ? 119.414 114.392 142.132 1.00 90.94 ? 570 GLY A O   1 
ATOM   4212 N  N   . PRO A 1 583 ? 120.708 116.211 142.455 1.00 93.16 ? 571 PRO A N   1 
ATOM   4213 C  CA  . PRO A 1 583 ? 119.546 117.102 142.541 1.00 93.16 ? 571 PRO A CA  1 
ATOM   4214 C  C   . PRO A 1 583 ? 118.870 117.161 141.187 1.00 93.16 ? 571 PRO A C   1 
ATOM   4215 O  O   . PRO A 1 583 ? 119.563 117.102 140.177 1.00 93.16 ? 571 PRO A O   1 
ATOM   4216 C  CB  . PRO A 1 583 ? 120.170 118.456 142.877 1.00 93.16 ? 571 PRO A CB  1 
ATOM   4217 C  CG  . PRO A 1 583 ? 121.473 118.124 143.523 1.00 93.16 ? 571 PRO A CG  1 
ATOM   4218 C  CD  . PRO A 1 583 ? 121.960 116.890 142.823 1.00 93.16 ? 571 PRO A CD  1 
ATOM   4219 N  N   . PHE A 1 584 ? 117.552 117.305 141.146 1.00 92.51 ? 572 PHE A N   1 
ATOM   4220 C  CA  . PHE A 1 584 ? 116.857 117.247 139.861 1.00 92.51 ? 572 PHE A CA  1 
ATOM   4221 C  C   . PHE A 1 584 ? 117.303 118.327 138.881 1.00 92.51 ? 572 PHE A C   1 
ATOM   4222 O  O   . PHE A 1 584 ? 117.472 118.048 137.700 1.00 92.51 ? 572 PHE A O   1 
ATOM   4223 C  CB  . PHE A 1 584 ? 115.327 117.244 140.037 1.00 92.51 ? 572 PHE A CB  1 
ATOM   4224 C  CG  . PHE A 1 584 ? 114.750 118.559 140.489 1.00 92.51 ? 572 PHE A CG  1 
ATOM   4225 C  CD1 . PHE A 1 584 ? 114.914 118.999 141.793 1.00 92.51 ? 572 PHE A CD1 1 
ATOM   4226 C  CD2 . PHE A 1 584 ? 114.016 119.341 139.612 1.00 92.51 ? 572 PHE A CD2 1 
ATOM   4227 C  CE1 . PHE A 1 584 ? 114.378 120.203 142.207 1.00 92.51 ? 572 PHE A CE1 1 
ATOM   4228 C  CE2 . PHE A 1 584 ? 113.475 120.545 140.022 1.00 92.51 ? 572 PHE A CE2 1 
ATOM   4229 C  CZ  . PHE A 1 584 ? 113.656 120.976 141.321 1.00 92.51 ? 572 PHE A CZ  1 
ATOM   4230 N  N   . LEU A 1 585 ? 117.522 119.545 139.360 1.00 92.32 ? 573 LEU A N   1 
ATOM   4231 C  CA  . LEU A 1 585 ? 118.002 120.595 138.479 1.00 92.32 ? 573 LEU A CA  1 
ATOM   4232 C  C   . LEU A 1 585 ? 119.372 120.256 137.918 1.00 92.32 ? 573 LEU A C   1 
ATOM   4233 O  O   . LEU A 1 585 ? 119.611 120.425 136.727 1.00 92.32 ? 573 LEU A O   1 
ATOM   4234 C  CB  . LEU A 1 585 ? 118.061 121.928 139.218 1.00 92.32 ? 573 LEU A CB  1 
ATOM   4235 C  CG  . LEU A 1 585 ? 116.705 122.561 139.524 1.00 92.32 ? 573 LEU A CG  1 
ATOM   4236 C  CD1 . LEU A 1 585 ? 116.866 123.798 140.392 1.00 92.32 ? 573 LEU A CD1 1 
ATOM   4237 C  CD2 . LEU A 1 585 ? 115.978 122.894 138.230 1.00 92.32 ? 573 LEU A CD2 1 
ATOM   4238 N  N   . VAL A 1 586 ? 120.262 119.748 138.763 1.00 91.67 ? 574 VAL A N   1 
ATOM   4239 C  CA  . VAL A 1 586 ? 121.594 119.368 138.306 1.00 91.67 ? 574 VAL A CA  1 
ATOM   4240 C  C   . VAL A 1 586 ? 121.515 118.236 137.292 1.00 91.67 ? 574 VAL A C   1 
ATOM   4241 O  O   . VAL A 1 586 ? 122.190 118.265 136.265 1.00 91.67 ? 574 VAL A O   1 
ATOM   4242 C  CB  . VAL A 1 586 ? 122.493 118.961 139.489 1.00 91.67 ? 574 VAL A CB  1 
ATOM   4243 C  CG1 . VAL A 1 586 ? 123.828 118.416 139.005 1.00 91.67 ? 574 VAL A CG1 1 
ATOM   4244 C  CG2 . VAL A 1 586 ? 122.707 120.149 140.413 1.00 91.67 ? 574 VAL A CG2 1 
ATOM   4245 N  N   . ARG A 1 587 ? 120.661 117.254 137.558 1.00 91.86 ? 575 ARG A N   1 
ATOM   4246 C  CA  . ARG A 1 587 ? 120.520 116.133 136.643 1.00 91.86 ? 575 ARG A CA  1 
ATOM   4247 C  C   . ARG A 1 587 ? 119.995 116.574 135.289 1.00 91.86 ? 575 ARG A C   1 
ATOM   4248 O  O   . ARG A 1 587 ? 120.482 116.120 134.260 1.00 91.86 ? 575 ARG A O   1 
ATOM   4249 C  CB  . ARG A 1 587 ? 119.589 115.079 137.228 1.00 91.86 ? 575 ARG A CB  1 
ATOM   4250 C  CG  . ARG A 1 587 ? 120.141 114.376 138.449 1.00 91.86 ? 575 ARG A CG  1 
ATOM   4251 C  CD  . ARG A 1 587 ? 119.188 113.296 138.918 1.00 91.86 ? 575 ARG A CD  1 
ATOM   4252 N  NE  . ARG A 1 587 ? 117.866 113.816 139.242 1.00 91.86 ? 575 ARG A NE  1 
ATOM   4253 C  CZ  . ARG A 1 587 ? 116.875 113.072 139.719 1.00 91.86 ? 575 ARG A CZ  1 
ATOM   4254 N  NH1 . ARG A 1 587 ? 117.063 111.777 139.930 1.00 91.86 ? 575 ARG A NH1 1 
ATOM   4255 N  NH2 . ARG A 1 587 ? 115.700 113.620 139.988 1.00 91.86 ? 575 ARG A NH2 1 
ATOM   4256 N  N   . VAL A 1 588 ? 119.011 117.466 135.288 1.00 94.01 ? 576 VAL A N   1 
ATOM   4257 C  CA  . VAL A 1 588 ? 118.454 117.949 134.035 1.00 94.01 ? 576 VAL A CA  1 
ATOM   4258 C  C   . VAL A 1 588 ? 119.546 118.666 133.263 1.00 94.01 ? 576 VAL A C   1 
ATOM   4259 O  O   . VAL A 1 588 ? 119.748 118.403 132.083 1.00 94.01 ? 576 VAL A O   1 
ATOM   4260 C  CB  . VAL A 1 588 ? 117.254 118.886 134.267 1.00 94.01 ? 576 VAL A CB  1 
ATOM   4261 C  CG1 . VAL A 1 588 ? 116.907 119.658 133.004 1.00 94.01 ? 576 VAL A CG1 1 
ATOM   4262 C  CG2 . VAL A 1 588 ? 116.050 118.093 134.745 1.00 94.01 ? 576 VAL A CG2 1 
ATOM   4263 N  N   . LYS A 1 589 ? 120.275 119.547 133.936 1.00 91.82 ? 577 LYS A N   1 
ATOM   4264 C  CA  . LYS A 1 589 ? 121.330 120.302 133.276 1.00 91.82 ? 577 LYS A CA  1 
ATOM   4265 C  C   . LYS A 1 589 ? 122.417 119.407 132.705 1.00 91.82 ? 577 LYS A C   1 
ATOM   4266 O  O   . LYS A 1 589 ? 122.868 119.614 131.582 1.00 91.82 ? 577 LYS A O   1 
ATOM   4267 C  CB  . LYS A 1 589 ? 121.939 121.337 134.221 1.00 91.82 ? 577 LYS A CB  1 
ATOM   4268 C  CG  . LYS A 1 589 ? 120.980 122.452 134.599 1.00 91.82 ? 577 LYS A CG  1 
ATOM   4269 C  CD  . LYS A 1 589 ? 120.276 123.009 133.374 1.00 91.82 ? 577 LYS A CD  1 
ATOM   4270 C  CE  . LYS A 1 589 ? 119.062 123.830 133.772 1.00 91.82 ? 577 LYS A CE  1 
ATOM   4271 N  NZ  . LYS A 1 589 ? 118.104 123.023 134.577 1.00 91.82 ? 577 LYS A NZ  1 
ATOM   4272 N  N   . TYR A 1 590 ? 122.832 118.404 133.469 1.00 90.23 ? 578 TYR A N   1 
ATOM   4273 C  CA  . TYR A 1 590 ? 123.848 117.486 132.979 1.00 90.23 ? 578 TYR A CA  1 
ATOM   4274 C  C   . TYR A 1 590 ? 123.340 116.711 131.775 1.00 90.23 ? 578 TYR A C   1 
ATOM   4275 O  O   . TYR A 1 590 ? 124.048 116.554 130.781 1.00 90.23 ? 578 TYR A O   1 
ATOM   4276 C  CB  . TYR A 1 590 ? 124.270 116.527 134.095 1.00 90.23 ? 578 TYR A CB  1 
ATOM   4277 C  CG  . TYR A 1 590 ? 125.017 115.301 133.623 1.00 90.23 ? 578 TYR A CG  1 
ATOM   4278 C  CD1 . TYR A 1 590 ? 126.310 115.399 133.125 1.00 90.23 ? 578 TYR A CD1 1 
ATOM   4279 C  CD2 . TYR A 1 590 ? 124.434 114.042 133.688 1.00 90.23 ? 578 TYR A CD2 1 
ATOM   4280 C  CE1 . TYR A 1 590 ? 126.995 114.280 132.693 1.00 90.23 ? 578 TYR A CE1 1 
ATOM   4281 C  CE2 . TYR A 1 590 ? 125.111 112.919 133.259 1.00 90.23 ? 578 TYR A CE2 1 
ATOM   4282 C  CZ  . TYR A 1 590 ? 126.392 113.043 132.765 1.00 90.23 ? 578 TYR A CZ  1 
ATOM   4283 O  OH  . TYR A 1 590 ? 127.072 111.926 132.339 1.00 90.23 ? 578 TYR A OH  1 
ATOM   4284 N  N   . LEU A 1 591 ? 122.109 116.224 131.859 1.00 93.07 ? 579 LEU A N   1 
ATOM   4285 C  CA  . LEU A 1 591 ? 121.528 115.491 130.743 1.00 93.07 ? 579 LEU A CA  1 
ATOM   4286 C  C   . LEU A 1 591 ? 121.284 116.340 129.502 1.00 93.07 ? 579 LEU A C   1 
ATOM   4287 O  O   . LEU A 1 591 ? 121.503 115.883 128.396 1.00 93.07 ? 579 LEU A O   1 
ATOM   4288 C  CB  . LEU A 1 591 ? 120.273 114.735 131.174 1.00 93.07 ? 579 LEU A CB  1 
ATOM   4289 C  CG  . LEU A 1 591 ? 120.617 113.490 131.993 1.00 93.07 ? 579 LEU A CG  1 
ATOM   4290 C  CD1 . LEU A 1 591 ? 119.371 112.692 132.324 1.00 93.07 ? 579 LEU A CD1 1 
ATOM   4291 C  CD2 . LEU A 1 591 ? 121.610 112.628 131.232 1.00 93.07 ? 579 LEU A CD2 1 
ATOM   4292 N  N   . LEU A 1 592 ? 120.819 117.570 129.677 1.00 94.17 ? 580 LEU A N   1 
ATOM   4293 C  CA  . LEU A 1 592 ? 120.516 118.414 128.527 1.00 94.17 ? 580 LEU A CA  1 
ATOM   4294 C  C   . LEU A 1 592 ? 121.755 118.723 127.708 1.00 94.17 ? 580 LEU A C   1 
ATOM   4295 O  O   . LEU A 1 592 ? 121.704 118.724 126.479 1.00 94.17 ? 580 LEU A O   1 
ATOM   4296 C  CB  . LEU A 1 592 ? 119.820 119.708 128.943 1.00 94.17 ? 580 LEU A CB  1 
ATOM   4297 C  CG  . LEU A 1 592 ? 118.324 119.578 129.224 1.00 94.17 ? 580 LEU A CG  1 
ATOM   4298 C  CD1 . LEU A 1 592 ? 117.696 120.955 129.356 1.00 94.17 ? 580 LEU A CD1 1 
ATOM   4299 C  CD2 . LEU A 1 592 ? 117.641 118.784 128.122 1.00 94.17 ? 580 LEU A CD2 1 
ATOM   4300 N  N   . THR A 1 593 ? 122.869 118.982 128.382 1.00 90.02 ? 581 THR A N   1 
ATOM   4301 C  CA  . THR A 1 593 ? 124.104 119.290 127.675 1.00 90.02 ? 581 THR A CA  1 
ATOM   4302 C  C   . THR A 1 593 ? 124.537 118.090 126.851 1.00 90.02 ? 581 THR A C   1 
ATOM   4303 O  O   . THR A 1 593 ? 124.477 116.959 127.329 1.00 90.02 ? 581 THR A O   1 
ATOM   4304 C  CB  . THR A 1 593 ? 125.235 119.688 128.642 1.00 90.02 ? 581 THR A CB  1 
ATOM   4305 O  OG1 . THR A 1 593 ? 125.386 118.683 129.650 1.00 90.02 ? 581 THR A OG1 1 
ATOM   4306 C  CG2 . THR A 1 593 ? 124.925 121.019 129.304 1.00 90.02 ? 581 THR A CG2 1 
ATOM   4307 N  N   . PRO A 1 594 ? 125.005 118.333 125.618 1.00 87.27 ? 582 PRO A N   1 
ATOM   4308 C  CA  . PRO A 1 594 ? 125.360 117.213 124.742 1.00 87.27 ? 582 PRO A CA  1 
ATOM   4309 C  C   . PRO A 1 594 ? 126.458 116.376 125.358 1.00 87.27 ? 582 PRO A C   1 
ATOM   4310 O  O   . PRO A 1 594 ? 127.424 116.928 125.881 1.00 87.27 ? 582 PRO A O   1 
ATOM   4311 C  CB  . PRO A 1 594 ? 125.902 117.911 123.496 1.00 87.27 ? 582 PRO A CB  1 
ATOM   4312 C  CG  . PRO A 1 594 ? 125.244 119.247 123.489 1.00 87.27 ? 582 PRO A CG  1 
ATOM   4313 C  CD  . PRO A 1 594 ? 125.091 119.633 124.929 1.00 87.27 ? 582 PRO A CD  1 
ATOM   4314 N  N   . ARG A 1 595 ? 126.321 115.057 125.294 1.00 77.75 ? 583 ARG A N   1 
ATOM   4315 C  CA  . ARG A 1 595 ? 127.303 114.186 125.919 1.00 77.75 ? 583 ARG A CA  1 
ATOM   4316 C  C   . ARG A 1 595 ? 128.653 114.377 125.260 1.00 77.75 ? 583 ARG A C   1 
ATOM   4317 O  O   . ARG A 1 595 ? 129.666 114.507 125.950 1.00 77.75 ? 583 ARG A O   1 
ATOM   4318 C  CB  . ARG A 1 595 ? 126.871 112.728 125.775 1.00 77.75 ? 583 ARG A CB  1 
ATOM   4319 C  CG  . ARG A 1 595 ? 127.615 111.766 126.684 1.00 77.75 ? 583 ARG A CG  1 
ATOM   4320 C  CD  . ARG A 1 595 ? 126.925 111.656 128.032 1.00 77.75 ? 583 ARG A CD  1 
ATOM   4321 N  NE  . ARG A 1 595 ? 125.640 110.975 127.912 1.00 77.75 ? 583 ARG A NE  1 
ATOM   4322 C  CZ  . ARG A 1 595 ? 124.817 110.744 128.928 1.00 77.75 ? 583 ARG A CZ  1 
ATOM   4323 N  NH1 . ARG A 1 595 ? 125.139 111.142 130.150 1.00 77.75 ? 583 ARG A NH1 1 
ATOM   4324 N  NH2 . ARG A 1 595 ? 123.671 110.114 128.721 1.00 77.75 ? 583 ARG A NH2 1 
HETATM 4325 C  C1  . TAU B 2 .   ? 107.466 105.492 103.291 1.00 30.00 ? 701 TAU A C1  1 
HETATM 4326 C  C2  . TAU B 2 .   ? 108.552 106.021 102.386 1.00 30.00 ? 701 TAU A C2  1 
HETATM 4327 N  N1  . TAU B 2 .   ? 107.992 105.416 104.625 1.00 30.00 ? 701 TAU A N1  1 
HETATM 4328 S  S   . TAU B 2 .   ? 107.849 106.370 100.768 1.00 30.00 ? 701 TAU A S   1 
HETATM 4329 O  O1  . TAU B 2 .   ? 108.523 105.589 99.693  1.00 30.00 ? 701 TAU A O1  1 
HETATM 4330 O  O2  . TAU B 2 .   ? 106.381 106.102 100.719 1.00 30.00 ? 701 TAU A O2  1 
HETATM 4331 O  O3  . TAU B 2 .   ? 108.155 107.752 100.290 1.00 30.00 ? 701 TAU A O3  1 
HETATM 4332 CL CL  . CL  C 3 .   ? 104.574 113.141 98.848  1.00 30.00 ? 702 CL  A CL  1 
# 
