data_9K7B
# 
_entry.id   9K7B 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9K7B         pdb_00009k7b 10.2210/pdb9k7b/pdb 
WWPDB D_1300052894 ?            ?                   
EMDB  EMD-62147    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-26 ? 
2 'EM metadata'     1 0 2025-02-26 ? 
3 FSC               1 0 2025-02-26 ? 
4 'Half map'        1 0 2025-02-26 1 
5 'Half map'        1 0 2025-02-26 2 
6 Image             1 0 2025-02-26 ? 
7 'Primary map'     1 0 2025-02-26 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9K7B 
_pdbx_database_status.recvd_initial_deposition_date   2024-10-23 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Cryo-EM structure of human taurine transporter TauT bound with taurine molecules in an inward-open state in the saposin-disc' 
_pdbx_database_related.db_id          EMD-62147 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              zhangheng@simm.ac.cn 
_pdbx_contact_author.name_first         Zhang 
_pdbx_contact_author.name_last          Heng 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-9441-8277 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zhang, H.' 1 ? 
'Xu, E.H.'  2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   CN 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Res.' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1001-0602 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Cryo-EM structure of human taurine transporter TauT bound with taurine molecules in an inward-open state in the saposin-disc' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zhang, H.' 1 ? 
primary 'Xu, E.H.'  2 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Sodium- and chloride-dependent taurine transporter' 71211.000 1  ? ? ? ? 
2 non-polymer syn '2-AMINOETHANESULFONIC ACID'                         125.147   4  ? ? ? ? 
3 non-polymer syn 'SODIUM ION'                                         22.990    1  ? ? ? ? 
4 non-polymer syn 'CHLORIDE ION'                                       35.453    1  ? ? ? ? 
5 non-polymer syn CHOLESTEROL                                          386.654   5  ? ? ? ? 
6 water       nat water                                                18.015    19 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Solute carrier family 6 member 6' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MDYKDDDDKGSGMATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFP
YLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYY
LFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVW
LVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGA
MTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWS
ILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCL
LWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWS
LALSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTPREPNRWAVEREGATPYNSRTVMNGALVKPTHIIVETMM
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MDYKDDDDKGSGMATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFP
YLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYY
LFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVW
LVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGA
MTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWS
ILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCL
LWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWS
LALSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTPREPNRWAVEREGATPYNSRTVMNGALVKPTHIIVETMM
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '2-AMINOETHANESULFONIC ACID' TAU 
3 'SODIUM ION'                 NA  
4 'CHLORIDE ION'               CL  
5 CHOLESTEROL                  CLR 
6 water                        HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ASP n 
1 3   TYR n 
1 4   LYS n 
1 5   ASP n 
1 6   ASP n 
1 7   ASP n 
1 8   ASP n 
1 9   LYS n 
1 10  GLY n 
1 11  SER n 
1 12  GLY n 
1 13  MET n 
1 14  ALA n 
1 15  THR n 
1 16  LYS n 
1 17  GLU n 
1 18  LYS n 
1 19  LEU n 
1 20  GLN n 
1 21  CYS n 
1 22  LEU n 
1 23  LYS n 
1 24  ASP n 
1 25  PHE n 
1 26  HIS n 
1 27  LYS n 
1 28  ASP n 
1 29  ILE n 
1 30  LEU n 
1 31  LYS n 
1 32  PRO n 
1 33  SER n 
1 34  PRO n 
1 35  GLY n 
1 36  LYS n 
1 37  SER n 
1 38  PRO n 
1 39  GLY n 
1 40  THR n 
1 41  ARG n 
1 42  PRO n 
1 43  GLU n 
1 44  ASP n 
1 45  GLU n 
1 46  ALA n 
1 47  GLU n 
1 48  GLY n 
1 49  LYS n 
1 50  PRO n 
1 51  PRO n 
1 52  GLN n 
1 53  ARG n 
1 54  GLU n 
1 55  LYS n 
1 56  TRP n 
1 57  SER n 
1 58  SER n 
1 59  LYS n 
1 60  ILE n 
1 61  ASP n 
1 62  PHE n 
1 63  VAL n 
1 64  LEU n 
1 65  SER n 
1 66  VAL n 
1 67  ALA n 
1 68  GLY n 
1 69  GLY n 
1 70  PHE n 
1 71  VAL n 
1 72  GLY n 
1 73  LEU n 
1 74  GLY n 
1 75  ASN n 
1 76  VAL n 
1 77  TRP n 
1 78  ARG n 
1 79  PHE n 
1 80  PRO n 
1 81  TYR n 
1 82  LEU n 
1 83  CYS n 
1 84  TYR n 
1 85  LYS n 
1 86  ASN n 
1 87  GLY n 
1 88  GLY n 
1 89  GLY n 
1 90  ALA n 
1 91  PHE n 
1 92  LEU n 
1 93  ILE n 
1 94  PRO n 
1 95  TYR n 
1 96  PHE n 
1 97  ILE n 
1 98  PHE n 
1 99  LEU n 
1 100 PHE n 
1 101 GLY n 
1 102 SER n 
1 103 GLY n 
1 104 LEU n 
1 105 PRO n 
1 106 VAL n 
1 107 PHE n 
1 108 PHE n 
1 109 LEU n 
1 110 GLU n 
1 111 ILE n 
1 112 ILE n 
1 113 ILE n 
1 114 GLY n 
1 115 GLN n 
1 116 TYR n 
1 117 THR n 
1 118 SER n 
1 119 GLU n 
1 120 GLY n 
1 121 GLY n 
1 122 ILE n 
1 123 THR n 
1 124 CYS n 
1 125 TRP n 
1 126 GLU n 
1 127 LYS n 
1 128 ILE n 
1 129 CYS n 
1 130 PRO n 
1 131 LEU n 
1 132 PHE n 
1 133 SER n 
1 134 GLY n 
1 135 ILE n 
1 136 GLY n 
1 137 TYR n 
1 138 ALA n 
1 139 SER n 
1 140 VAL n 
1 141 VAL n 
1 142 ILE n 
1 143 VAL n 
1 144 SER n 
1 145 LEU n 
1 146 LEU n 
1 147 ASN n 
1 148 VAL n 
1 149 TYR n 
1 150 TYR n 
1 151 ILE n 
1 152 VAL n 
1 153 ILE n 
1 154 LEU n 
1 155 ALA n 
1 156 TRP n 
1 157 ALA n 
1 158 THR n 
1 159 TYR n 
1 160 TYR n 
1 161 LEU n 
1 162 PHE n 
1 163 GLN n 
1 164 SER n 
1 165 PHE n 
1 166 GLN n 
1 167 LYS n 
1 168 GLU n 
1 169 LEU n 
1 170 PRO n 
1 171 TRP n 
1 172 ALA n 
1 173 HIS n 
1 174 CYS n 
1 175 ASN n 
1 176 HIS n 
1 177 SER n 
1 178 TRP n 
1 179 ASN n 
1 180 THR n 
1 181 PRO n 
1 182 HIS n 
1 183 CYS n 
1 184 MET n 
1 185 GLU n 
1 186 ASP n 
1 187 THR n 
1 188 MET n 
1 189 ARG n 
1 190 LYS n 
1 191 ASN n 
1 192 LYS n 
1 193 SER n 
1 194 VAL n 
1 195 TRP n 
1 196 ILE n 
1 197 THR n 
1 198 ILE n 
1 199 SER n 
1 200 SER n 
1 201 THR n 
1 202 ASN n 
1 203 PHE n 
1 204 THR n 
1 205 SER n 
1 206 PRO n 
1 207 VAL n 
1 208 ILE n 
1 209 GLU n 
1 210 PHE n 
1 211 TRP n 
1 212 GLU n 
1 213 ARG n 
1 214 ASN n 
1 215 VAL n 
1 216 LEU n 
1 217 SER n 
1 218 LEU n 
1 219 SER n 
1 220 PRO n 
1 221 GLY n 
1 222 ILE n 
1 223 ASP n 
1 224 HIS n 
1 225 PRO n 
1 226 GLY n 
1 227 SER n 
1 228 LEU n 
1 229 LYS n 
1 230 TRP n 
1 231 ASP n 
1 232 LEU n 
1 233 ALA n 
1 234 LEU n 
1 235 CYS n 
1 236 LEU n 
1 237 LEU n 
1 238 LEU n 
1 239 VAL n 
1 240 TRP n 
1 241 LEU n 
1 242 VAL n 
1 243 CYS n 
1 244 PHE n 
1 245 PHE n 
1 246 CYS n 
1 247 ILE n 
1 248 TRP n 
1 249 LYS n 
1 250 GLY n 
1 251 VAL n 
1 252 ARG n 
1 253 SER n 
1 254 THR n 
1 255 GLY n 
1 256 LYS n 
1 257 VAL n 
1 258 VAL n 
1 259 TYR n 
1 260 PHE n 
1 261 THR n 
1 262 ALA n 
1 263 THR n 
1 264 PHE n 
1 265 PRO n 
1 266 PHE n 
1 267 ALA n 
1 268 MET n 
1 269 LEU n 
1 270 LEU n 
1 271 VAL n 
1 272 LEU n 
1 273 LEU n 
1 274 VAL n 
1 275 ARG n 
1 276 GLY n 
1 277 LEU n 
1 278 THR n 
1 279 LEU n 
1 280 PRO n 
1 281 GLY n 
1 282 ALA n 
1 283 GLY n 
1 284 ALA n 
1 285 GLY n 
1 286 ILE n 
1 287 LYS n 
1 288 PHE n 
1 289 TYR n 
1 290 LEU n 
1 291 TYR n 
1 292 PRO n 
1 293 ASP n 
1 294 ILE n 
1 295 THR n 
1 296 ARG n 
1 297 LEU n 
1 298 GLU n 
1 299 ASP n 
1 300 PRO n 
1 301 GLN n 
1 302 VAL n 
1 303 TRP n 
1 304 ILE n 
1 305 ASP n 
1 306 ALA n 
1 307 GLY n 
1 308 THR n 
1 309 GLN n 
1 310 ILE n 
1 311 PHE n 
1 312 PHE n 
1 313 SER n 
1 314 TYR n 
1 315 ALA n 
1 316 ILE n 
1 317 CYS n 
1 318 LEU n 
1 319 GLY n 
1 320 ALA n 
1 321 MET n 
1 322 THR n 
1 323 SER n 
1 324 LEU n 
1 325 GLY n 
1 326 SER n 
1 327 TYR n 
1 328 ASN n 
1 329 LYS n 
1 330 TYR n 
1 331 LYS n 
1 332 TYR n 
1 333 ASN n 
1 334 SER n 
1 335 TYR n 
1 336 ARG n 
1 337 ASP n 
1 338 CYS n 
1 339 MET n 
1 340 LEU n 
1 341 LEU n 
1 342 GLY n 
1 343 CYS n 
1 344 LEU n 
1 345 ASN n 
1 346 SER n 
1 347 GLY n 
1 348 THR n 
1 349 SER n 
1 350 PHE n 
1 351 VAL n 
1 352 SER n 
1 353 GLY n 
1 354 PHE n 
1 355 ALA n 
1 356 ILE n 
1 357 PHE n 
1 358 SER n 
1 359 ILE n 
1 360 LEU n 
1 361 GLY n 
1 362 PHE n 
1 363 MET n 
1 364 ALA n 
1 365 GLN n 
1 366 GLU n 
1 367 GLN n 
1 368 GLY n 
1 369 VAL n 
1 370 ASP n 
1 371 ILE n 
1 372 ALA n 
1 373 ASP n 
1 374 VAL n 
1 375 ALA n 
1 376 GLU n 
1 377 SER n 
1 378 GLY n 
1 379 PRO n 
1 380 GLY n 
1 381 LEU n 
1 382 ALA n 
1 383 PHE n 
1 384 ILE n 
1 385 ALA n 
1 386 TYR n 
1 387 PRO n 
1 388 LYS n 
1 389 ALA n 
1 390 VAL n 
1 391 THR n 
1 392 MET n 
1 393 MET n 
1 394 PRO n 
1 395 LEU n 
1 396 PRO n 
1 397 THR n 
1 398 PHE n 
1 399 TRP n 
1 400 SER n 
1 401 ILE n 
1 402 LEU n 
1 403 PHE n 
1 404 PHE n 
1 405 ILE n 
1 406 MET n 
1 407 LEU n 
1 408 LEU n 
1 409 LEU n 
1 410 LEU n 
1 411 GLY n 
1 412 LEU n 
1 413 ASP n 
1 414 SER n 
1 415 GLN n 
1 416 PHE n 
1 417 VAL n 
1 418 GLU n 
1 419 VAL n 
1 420 GLU n 
1 421 GLY n 
1 422 GLN n 
1 423 ILE n 
1 424 THR n 
1 425 SER n 
1 426 LEU n 
1 427 VAL n 
1 428 ASP n 
1 429 LEU n 
1 430 TYR n 
1 431 PRO n 
1 432 SER n 
1 433 PHE n 
1 434 LEU n 
1 435 ARG n 
1 436 LYS n 
1 437 GLY n 
1 438 TYR n 
1 439 ARG n 
1 440 ARG n 
1 441 GLU n 
1 442 ILE n 
1 443 PHE n 
1 444 ILE n 
1 445 ALA n 
1 446 PHE n 
1 447 VAL n 
1 448 CYS n 
1 449 SER n 
1 450 ILE n 
1 451 SER n 
1 452 TYR n 
1 453 LEU n 
1 454 LEU n 
1 455 GLY n 
1 456 LEU n 
1 457 THR n 
1 458 MET n 
1 459 VAL n 
1 460 THR n 
1 461 GLU n 
1 462 GLY n 
1 463 GLY n 
1 464 MET n 
1 465 TYR n 
1 466 VAL n 
1 467 PHE n 
1 468 GLN n 
1 469 LEU n 
1 470 PHE n 
1 471 ASP n 
1 472 TYR n 
1 473 TYR n 
1 474 ALA n 
1 475 ALA n 
1 476 SER n 
1 477 GLY n 
1 478 VAL n 
1 479 CYS n 
1 480 LEU n 
1 481 LEU n 
1 482 TRP n 
1 483 VAL n 
1 484 ALA n 
1 485 PHE n 
1 486 PHE n 
1 487 GLU n 
1 488 CYS n 
1 489 PHE n 
1 490 VAL n 
1 491 ILE n 
1 492 ALA n 
1 493 TRP n 
1 494 ILE n 
1 495 TYR n 
1 496 GLY n 
1 497 GLY n 
1 498 ASP n 
1 499 ASN n 
1 500 LEU n 
1 501 TYR n 
1 502 ASP n 
1 503 GLY n 
1 504 ILE n 
1 505 GLU n 
1 506 ASP n 
1 507 MET n 
1 508 ILE n 
1 509 GLY n 
1 510 TYR n 
1 511 ARG n 
1 512 PRO n 
1 513 GLY n 
1 514 PRO n 
1 515 TRP n 
1 516 MET n 
1 517 LYS n 
1 518 TYR n 
1 519 SER n 
1 520 TRP n 
1 521 ALA n 
1 522 VAL n 
1 523 ILE n 
1 524 THR n 
1 525 PRO n 
1 526 VAL n 
1 527 LEU n 
1 528 CYS n 
1 529 VAL n 
1 530 GLY n 
1 531 CYS n 
1 532 PHE n 
1 533 ILE n 
1 534 PHE n 
1 535 SER n 
1 536 LEU n 
1 537 VAL n 
1 538 LYS n 
1 539 TYR n 
1 540 VAL n 
1 541 PRO n 
1 542 LEU n 
1 543 THR n 
1 544 TYR n 
1 545 ASN n 
1 546 LYS n 
1 547 THR n 
1 548 TYR n 
1 549 VAL n 
1 550 TYR n 
1 551 PRO n 
1 552 ASN n 
1 553 TRP n 
1 554 ALA n 
1 555 ILE n 
1 556 GLY n 
1 557 LEU n 
1 558 GLY n 
1 559 TRP n 
1 560 SER n 
1 561 LEU n 
1 562 ALA n 
1 563 LEU n 
1 564 SER n 
1 565 SER n 
1 566 MET n 
1 567 LEU n 
1 568 CYS n 
1 569 VAL n 
1 570 PRO n 
1 571 LEU n 
1 572 VAL n 
1 573 ILE n 
1 574 VAL n 
1 575 ILE n 
1 576 ARG n 
1 577 LEU n 
1 578 CYS n 
1 579 GLN n 
1 580 THR n 
1 581 GLU n 
1 582 GLY n 
1 583 PRO n 
1 584 PHE n 
1 585 LEU n 
1 586 VAL n 
1 587 ARG n 
1 588 VAL n 
1 589 LYS n 
1 590 TYR n 
1 591 LEU n 
1 592 LEU n 
1 593 THR n 
1 594 PRO n 
1 595 ARG n 
1 596 GLU n 
1 597 PRO n 
1 598 ASN n 
1 599 ARG n 
1 600 TRP n 
1 601 ALA n 
1 602 VAL n 
1 603 GLU n 
1 604 ARG n 
1 605 GLU n 
1 606 GLY n 
1 607 ALA n 
1 608 THR n 
1 609 PRO n 
1 610 TYR n 
1 611 ASN n 
1 612 SER n 
1 613 ARG n 
1 614 THR n 
1 615 VAL n 
1 616 MET n 
1 617 ASN n 
1 618 GLY n 
1 619 ALA n 
1 620 LEU n 
1 621 VAL n 
1 622 LYS n 
1 623 PRO n 
1 624 THR n 
1 625 HIS n 
1 626 ILE n 
1 627 ILE n 
1 628 VAL n 
1 629 GLU n 
1 630 THR n 
1 631 MET n 
1 632 MET n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   632 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 SLC6A6 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                      ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                     ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                   ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'              ? 'C4 H7 N O4'     133.103 
CL  non-polymer         . 'CHLORIDE ION'               ? 'Cl -1'          35.453  
CLR non-polymer         . CHOLESTEROL                  ? 'C27 H46 O'      386.654 
CYS 'L-peptide linking' y CYSTEINE                     ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                    ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'              ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                      ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                    ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                        ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                   ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                      ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                       ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                   ? 'C5 H11 N O2 S'  149.211 
NA  non-polymer         . 'SODIUM ION'                 ? 'Na 1'           22.990  
PHE 'L-peptide linking' y PHENYLALANINE                ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                      ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                       ? 'C3 H7 N O3'     105.093 
TAU non-polymer         . '2-AMINOETHANESULFONIC ACID' ? 'C2 H7 N O3 S'   125.147 
THR 'L-peptide linking' y THREONINE                    ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                   ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                     ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                       ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -11 ?   ?   ?   A . n 
A 1 2   ASP 2   -10 ?   ?   ?   A . n 
A 1 3   TYR 3   -9  ?   ?   ?   A . n 
A 1 4   LYS 4   -8  ?   ?   ?   A . n 
A 1 5   ASP 5   -7  ?   ?   ?   A . n 
A 1 6   ASP 6   -6  ?   ?   ?   A . n 
A 1 7   ASP 7   -5  ?   ?   ?   A . n 
A 1 8   ASP 8   -4  ?   ?   ?   A . n 
A 1 9   LYS 9   -3  ?   ?   ?   A . n 
A 1 10  GLY 10  -2  ?   ?   ?   A . n 
A 1 11  SER 11  -1  ?   ?   ?   A . n 
A 1 12  GLY 12  0   ?   ?   ?   A . n 
A 1 13  MET 13  1   ?   ?   ?   A . n 
A 1 14  ALA 14  2   ?   ?   ?   A . n 
A 1 15  THR 15  3   ?   ?   ?   A . n 
A 1 16  LYS 16  4   ?   ?   ?   A . n 
A 1 17  GLU 17  5   ?   ?   ?   A . n 
A 1 18  LYS 18  6   ?   ?   ?   A . n 
A 1 19  LEU 19  7   ?   ?   ?   A . n 
A 1 20  GLN 20  8   ?   ?   ?   A . n 
A 1 21  CYS 21  9   ?   ?   ?   A . n 
A 1 22  LEU 22  10  ?   ?   ?   A . n 
A 1 23  LYS 23  11  ?   ?   ?   A . n 
A 1 24  ASP 24  12  ?   ?   ?   A . n 
A 1 25  PHE 25  13  ?   ?   ?   A . n 
A 1 26  HIS 26  14  ?   ?   ?   A . n 
A 1 27  LYS 27  15  ?   ?   ?   A . n 
A 1 28  ASP 28  16  ?   ?   ?   A . n 
A 1 29  ILE 29  17  ?   ?   ?   A . n 
A 1 30  LEU 30  18  ?   ?   ?   A . n 
A 1 31  LYS 31  19  ?   ?   ?   A . n 
A 1 32  PRO 32  20  ?   ?   ?   A . n 
A 1 33  SER 33  21  ?   ?   ?   A . n 
A 1 34  PRO 34  22  ?   ?   ?   A . n 
A 1 35  GLY 35  23  ?   ?   ?   A . n 
A 1 36  LYS 36  24  ?   ?   ?   A . n 
A 1 37  SER 37  25  ?   ?   ?   A . n 
A 1 38  PRO 38  26  ?   ?   ?   A . n 
A 1 39  GLY 39  27  ?   ?   ?   A . n 
A 1 40  THR 40  28  ?   ?   ?   A . n 
A 1 41  ARG 41  29  ?   ?   ?   A . n 
A 1 42  PRO 42  30  ?   ?   ?   A . n 
A 1 43  GLU 43  31  ?   ?   ?   A . n 
A 1 44  ASP 44  32  ?   ?   ?   A . n 
A 1 45  GLU 45  33  ?   ?   ?   A . n 
A 1 46  ALA 46  34  ?   ?   ?   A . n 
A 1 47  GLU 47  35  ?   ?   ?   A . n 
A 1 48  GLY 48  36  ?   ?   ?   A . n 
A 1 49  LYS 49  37  ?   ?   ?   A . n 
A 1 50  PRO 50  38  ?   ?   ?   A . n 
A 1 51  PRO 51  39  ?   ?   ?   A . n 
A 1 52  GLN 52  40  ?   ?   ?   A . n 
A 1 53  ARG 53  41  ?   ?   ?   A . n 
A 1 54  GLU 54  42  ?   ?   ?   A . n 
A 1 55  LYS 55  43  ?   ?   ?   A . n 
A 1 56  TRP 56  44  ?   ?   ?   A . n 
A 1 57  SER 57  45  45  SER SER A . n 
A 1 58  SER 58  46  46  SER SER A . n 
A 1 59  LYS 59  47  47  LYS LYS A . n 
A 1 60  ILE 60  48  48  ILE ILE A . n 
A 1 61  ASP 61  49  49  ASP ASP A . n 
A 1 62  PHE 62  50  50  PHE PHE A . n 
A 1 63  VAL 63  51  51  VAL VAL A . n 
A 1 64  LEU 64  52  52  LEU LEU A . n 
A 1 65  SER 65  53  53  SER SER A . n 
A 1 66  VAL 66  54  54  VAL VAL A . n 
A 1 67  ALA 67  55  55  ALA ALA A . n 
A 1 68  GLY 68  56  56  GLY GLY A . n 
A 1 69  GLY 69  57  57  GLY GLY A . n 
A 1 70  PHE 70  58  58  PHE PHE A . n 
A 1 71  VAL 71  59  59  VAL VAL A . n 
A 1 72  GLY 72  60  60  GLY GLY A . n 
A 1 73  LEU 73  61  61  LEU LEU A . n 
A 1 74  GLY 74  62  62  GLY GLY A . n 
A 1 75  ASN 75  63  63  ASN ASN A . n 
A 1 76  VAL 76  64  64  VAL VAL A . n 
A 1 77  TRP 77  65  65  TRP TRP A . n 
A 1 78  ARG 78  66  66  ARG ARG A . n 
A 1 79  PHE 79  67  67  PHE PHE A . n 
A 1 80  PRO 80  68  68  PRO PRO A . n 
A 1 81  TYR 81  69  69  TYR TYR A . n 
A 1 82  LEU 82  70  70  LEU LEU A . n 
A 1 83  CYS 83  71  71  CYS CYS A . n 
A 1 84  TYR 84  72  72  TYR TYR A . n 
A 1 85  LYS 85  73  73  LYS LYS A . n 
A 1 86  ASN 86  74  74  ASN ASN A . n 
A 1 87  GLY 87  75  75  GLY GLY A . n 
A 1 88  GLY 88  76  76  GLY GLY A . n 
A 1 89  GLY 89  77  77  GLY GLY A . n 
A 1 90  ALA 90  78  78  ALA ALA A . n 
A 1 91  PHE 91  79  79  PHE PHE A . n 
A 1 92  LEU 92  80  80  LEU LEU A . n 
A 1 93  ILE 93  81  81  ILE ILE A . n 
A 1 94  PRO 94  82  82  PRO PRO A . n 
A 1 95  TYR 95  83  83  TYR TYR A . n 
A 1 96  PHE 96  84  84  PHE PHE A . n 
A 1 97  ILE 97  85  85  ILE ILE A . n 
A 1 98  PHE 98  86  86  PHE PHE A . n 
A 1 99  LEU 99  87  87  LEU LEU A . n 
A 1 100 PHE 100 88  88  PHE PHE A . n 
A 1 101 GLY 101 89  89  GLY GLY A . n 
A 1 102 SER 102 90  90  SER SER A . n 
A 1 103 GLY 103 91  91  GLY GLY A . n 
A 1 104 LEU 104 92  92  LEU LEU A . n 
A 1 105 PRO 105 93  93  PRO PRO A . n 
A 1 106 VAL 106 94  94  VAL VAL A . n 
A 1 107 PHE 107 95  95  PHE PHE A . n 
A 1 108 PHE 108 96  96  PHE PHE A . n 
A 1 109 LEU 109 97  97  LEU LEU A . n 
A 1 110 GLU 110 98  98  GLU GLU A . n 
A 1 111 ILE 111 99  99  ILE ILE A . n 
A 1 112 ILE 112 100 100 ILE ILE A . n 
A 1 113 ILE 113 101 101 ILE ILE A . n 
A 1 114 GLY 114 102 102 GLY GLY A . n 
A 1 115 GLN 115 103 103 GLN GLN A . n 
A 1 116 TYR 116 104 104 TYR TYR A . n 
A 1 117 THR 117 105 105 THR THR A . n 
A 1 118 SER 118 106 106 SER SER A . n 
A 1 119 GLU 119 107 107 GLU GLU A . n 
A 1 120 GLY 120 108 108 GLY GLY A . n 
A 1 121 GLY 121 109 109 GLY GLY A . n 
A 1 122 ILE 122 110 110 ILE ILE A . n 
A 1 123 THR 123 111 111 THR THR A . n 
A 1 124 CYS 124 112 112 CYS CYS A . n 
A 1 125 TRP 125 113 113 TRP TRP A . n 
A 1 126 GLU 126 114 114 GLU GLU A . n 
A 1 127 LYS 127 115 115 LYS LYS A . n 
A 1 128 ILE 128 116 116 ILE ILE A . n 
A 1 129 CYS 129 117 117 CYS CYS A . n 
A 1 130 PRO 130 118 118 PRO PRO A . n 
A 1 131 LEU 131 119 119 LEU LEU A . n 
A 1 132 PHE 132 120 120 PHE PHE A . n 
A 1 133 SER 133 121 121 SER SER A . n 
A 1 134 GLY 134 122 122 GLY GLY A . n 
A 1 135 ILE 135 123 123 ILE ILE A . n 
A 1 136 GLY 136 124 124 GLY GLY A . n 
A 1 137 TYR 137 125 125 TYR TYR A . n 
A 1 138 ALA 138 126 126 ALA ALA A . n 
A 1 139 SER 139 127 127 SER SER A . n 
A 1 140 VAL 140 128 128 VAL VAL A . n 
A 1 141 VAL 141 129 129 VAL VAL A . n 
A 1 142 ILE 142 130 130 ILE ILE A . n 
A 1 143 VAL 143 131 131 VAL VAL A . n 
A 1 144 SER 144 132 132 SER SER A . n 
A 1 145 LEU 145 133 133 LEU LEU A . n 
A 1 146 LEU 146 134 134 LEU LEU A . n 
A 1 147 ASN 147 135 135 ASN ASN A . n 
A 1 148 VAL 148 136 136 VAL VAL A . n 
A 1 149 TYR 149 137 137 TYR TYR A . n 
A 1 150 TYR 150 138 138 TYR TYR A . n 
A 1 151 ILE 151 139 139 ILE ILE A . n 
A 1 152 VAL 152 140 140 VAL VAL A . n 
A 1 153 ILE 153 141 141 ILE ILE A . n 
A 1 154 LEU 154 142 142 LEU LEU A . n 
A 1 155 ALA 155 143 143 ALA ALA A . n 
A 1 156 TRP 156 144 144 TRP TRP A . n 
A 1 157 ALA 157 145 145 ALA ALA A . n 
A 1 158 THR 158 146 146 THR THR A . n 
A 1 159 TYR 159 147 147 TYR TYR A . n 
A 1 160 TYR 160 148 148 TYR TYR A . n 
A 1 161 LEU 161 149 149 LEU LEU A . n 
A 1 162 PHE 162 150 150 PHE PHE A . n 
A 1 163 GLN 163 151 151 GLN GLN A . n 
A 1 164 SER 164 152 152 SER SER A . n 
A 1 165 PHE 165 153 153 PHE PHE A . n 
A 1 166 GLN 166 154 154 GLN GLN A . n 
A 1 167 LYS 167 155 155 LYS LYS A . n 
A 1 168 GLU 168 156 156 GLU GLU A . n 
A 1 169 LEU 169 157 157 LEU LEU A . n 
A 1 170 PRO 170 158 158 PRO PRO A . n 
A 1 171 TRP 171 159 159 TRP TRP A . n 
A 1 172 ALA 172 160 160 ALA ALA A . n 
A 1 173 HIS 173 161 161 HIS HIS A . n 
A 1 174 CYS 174 162 162 CYS CYS A . n 
A 1 175 ASN 175 163 163 ASN ASN A . n 
A 1 176 HIS 176 164 164 HIS HIS A . n 
A 1 177 SER 177 165 165 SER SER A . n 
A 1 178 TRP 178 166 166 TRP TRP A . n 
A 1 179 ASN 179 167 167 ASN ASN A . n 
A 1 180 THR 180 168 168 THR THR A . n 
A 1 181 PRO 181 169 169 PRO PRO A . n 
A 1 182 HIS 182 170 170 HIS HIS A . n 
A 1 183 CYS 183 171 171 CYS CYS A . n 
A 1 184 MET 184 172 172 MET MET A . n 
A 1 185 GLU 185 173 173 GLU GLU A . n 
A 1 186 ASP 186 174 174 ASP ASP A . n 
A 1 187 THR 187 175 175 THR THR A . n 
A 1 188 MET 188 176 176 MET MET A . n 
A 1 189 ARG 189 177 177 ARG ARG A . n 
A 1 190 LYS 190 178 178 LYS LYS A . n 
A 1 191 ASN 191 179 179 ASN ASN A . n 
A 1 192 LYS 192 180 180 LYS LYS A . n 
A 1 193 SER 193 181 181 SER SER A . n 
A 1 194 VAL 194 182 182 VAL VAL A . n 
A 1 195 TRP 195 183 183 TRP TRP A . n 
A 1 196 ILE 196 184 184 ILE ILE A . n 
A 1 197 THR 197 185 185 THR THR A . n 
A 1 198 ILE 198 186 186 ILE ILE A . n 
A 1 199 SER 199 187 187 SER SER A . n 
A 1 200 SER 200 188 188 SER SER A . n 
A 1 201 THR 201 189 189 THR THR A . n 
A 1 202 ASN 202 190 190 ASN ASN A . n 
A 1 203 PHE 203 191 191 PHE PHE A . n 
A 1 204 THR 204 192 192 THR THR A . n 
A 1 205 SER 205 193 193 SER SER A . n 
A 1 206 PRO 206 194 194 PRO PRO A . n 
A 1 207 VAL 207 195 195 VAL VAL A . n 
A 1 208 ILE 208 196 196 ILE ILE A . n 
A 1 209 GLU 209 197 197 GLU GLU A . n 
A 1 210 PHE 210 198 198 PHE PHE A . n 
A 1 211 TRP 211 199 199 TRP TRP A . n 
A 1 212 GLU 212 200 200 GLU GLU A . n 
A 1 213 ARG 213 201 201 ARG ARG A . n 
A 1 214 ASN 214 202 202 ASN ASN A . n 
A 1 215 VAL 215 203 203 VAL VAL A . n 
A 1 216 LEU 216 204 204 LEU LEU A . n 
A 1 217 SER 217 205 205 SER SER A . n 
A 1 218 LEU 218 206 206 LEU LEU A . n 
A 1 219 SER 219 207 207 SER SER A . n 
A 1 220 PRO 220 208 208 PRO PRO A . n 
A 1 221 GLY 221 209 209 GLY GLY A . n 
A 1 222 ILE 222 210 210 ILE ILE A . n 
A 1 223 ASP 223 211 211 ASP ASP A . n 
A 1 224 HIS 224 212 212 HIS HIS A . n 
A 1 225 PRO 225 213 213 PRO PRO A . n 
A 1 226 GLY 226 214 214 GLY GLY A . n 
A 1 227 SER 227 215 215 SER SER A . n 
A 1 228 LEU 228 216 216 LEU LEU A . n 
A 1 229 LYS 229 217 217 LYS LYS A . n 
A 1 230 TRP 230 218 218 TRP TRP A . n 
A 1 231 ASP 231 219 219 ASP ASP A . n 
A 1 232 LEU 232 220 220 LEU LEU A . n 
A 1 233 ALA 233 221 221 ALA ALA A . n 
A 1 234 LEU 234 222 222 LEU LEU A . n 
A 1 235 CYS 235 223 223 CYS CYS A . n 
A 1 236 LEU 236 224 224 LEU LEU A . n 
A 1 237 LEU 237 225 225 LEU LEU A . n 
A 1 238 LEU 238 226 226 LEU LEU A . n 
A 1 239 VAL 239 227 227 VAL VAL A . n 
A 1 240 TRP 240 228 228 TRP TRP A . n 
A 1 241 LEU 241 229 229 LEU LEU A . n 
A 1 242 VAL 242 230 230 VAL VAL A . n 
A 1 243 CYS 243 231 231 CYS CYS A . n 
A 1 244 PHE 244 232 232 PHE PHE A . n 
A 1 245 PHE 245 233 233 PHE PHE A . n 
A 1 246 CYS 246 234 234 CYS CYS A . n 
A 1 247 ILE 247 235 235 ILE ILE A . n 
A 1 248 TRP 248 236 236 TRP TRP A . n 
A 1 249 LYS 249 237 237 LYS LYS A . n 
A 1 250 GLY 250 238 238 GLY GLY A . n 
A 1 251 VAL 251 239 239 VAL VAL A . n 
A 1 252 ARG 252 240 240 ARG ARG A . n 
A 1 253 SER 253 241 241 SER SER A . n 
A 1 254 THR 254 242 242 THR THR A . n 
A 1 255 GLY 255 243 243 GLY GLY A . n 
A 1 256 LYS 256 244 244 LYS LYS A . n 
A 1 257 VAL 257 245 245 VAL VAL A . n 
A 1 258 VAL 258 246 246 VAL VAL A . n 
A 1 259 TYR 259 247 247 TYR TYR A . n 
A 1 260 PHE 260 248 248 PHE PHE A . n 
A 1 261 THR 261 249 249 THR THR A . n 
A 1 262 ALA 262 250 250 ALA ALA A . n 
A 1 263 THR 263 251 251 THR THR A . n 
A 1 264 PHE 264 252 252 PHE PHE A . n 
A 1 265 PRO 265 253 253 PRO PRO A . n 
A 1 266 PHE 266 254 254 PHE PHE A . n 
A 1 267 ALA 267 255 255 ALA ALA A . n 
A 1 268 MET 268 256 256 MET MET A . n 
A 1 269 LEU 269 257 257 LEU LEU A . n 
A 1 270 LEU 270 258 258 LEU LEU A . n 
A 1 271 VAL 271 259 259 VAL VAL A . n 
A 1 272 LEU 272 260 260 LEU LEU A . n 
A 1 273 LEU 273 261 261 LEU LEU A . n 
A 1 274 VAL 274 262 262 VAL VAL A . n 
A 1 275 ARG 275 263 263 ARG ARG A . n 
A 1 276 GLY 276 264 264 GLY GLY A . n 
A 1 277 LEU 277 265 265 LEU LEU A . n 
A 1 278 THR 278 266 266 THR THR A . n 
A 1 279 LEU 279 267 267 LEU LEU A . n 
A 1 280 PRO 280 268 268 PRO PRO A . n 
A 1 281 GLY 281 269 269 GLY GLY A . n 
A 1 282 ALA 282 270 270 ALA ALA A . n 
A 1 283 GLY 283 271 271 GLY GLY A . n 
A 1 284 ALA 284 272 272 ALA ALA A . n 
A 1 285 GLY 285 273 273 GLY GLY A . n 
A 1 286 ILE 286 274 274 ILE ILE A . n 
A 1 287 LYS 287 275 275 LYS LYS A . n 
A 1 288 PHE 288 276 276 PHE PHE A . n 
A 1 289 TYR 289 277 277 TYR TYR A . n 
A 1 290 LEU 290 278 278 LEU LEU A . n 
A 1 291 TYR 291 279 279 TYR TYR A . n 
A 1 292 PRO 292 280 280 PRO PRO A . n 
A 1 293 ASP 293 281 281 ASP ASP A . n 
A 1 294 ILE 294 282 282 ILE ILE A . n 
A 1 295 THR 295 283 283 THR THR A . n 
A 1 296 ARG 296 284 284 ARG ARG A . n 
A 1 297 LEU 297 285 285 LEU LEU A . n 
A 1 298 GLU 298 286 286 GLU GLU A . n 
A 1 299 ASP 299 287 287 ASP ASP A . n 
A 1 300 PRO 300 288 288 PRO PRO A . n 
A 1 301 GLN 301 289 289 GLN GLN A . n 
A 1 302 VAL 302 290 290 VAL VAL A . n 
A 1 303 TRP 303 291 291 TRP TRP A . n 
A 1 304 ILE 304 292 292 ILE ILE A . n 
A 1 305 ASP 305 293 293 ASP ASP A . n 
A 1 306 ALA 306 294 294 ALA ALA A . n 
A 1 307 GLY 307 295 295 GLY GLY A . n 
A 1 308 THR 308 296 296 THR THR A . n 
A 1 309 GLN 309 297 297 GLN GLN A . n 
A 1 310 ILE 310 298 298 ILE ILE A . n 
A 1 311 PHE 311 299 299 PHE PHE A . n 
A 1 312 PHE 312 300 300 PHE PHE A . n 
A 1 313 SER 313 301 301 SER SER A . n 
A 1 314 TYR 314 302 302 TYR TYR A . n 
A 1 315 ALA 315 303 303 ALA ALA A . n 
A 1 316 ILE 316 304 304 ILE ILE A . n 
A 1 317 CYS 317 305 305 CYS CYS A . n 
A 1 318 LEU 318 306 306 LEU LEU A . n 
A 1 319 GLY 319 307 307 GLY GLY A . n 
A 1 320 ALA 320 308 308 ALA ALA A . n 
A 1 321 MET 321 309 309 MET MET A . n 
A 1 322 THR 322 310 310 THR THR A . n 
A 1 323 SER 323 311 311 SER SER A . n 
A 1 324 LEU 324 312 312 LEU LEU A . n 
A 1 325 GLY 325 313 313 GLY GLY A . n 
A 1 326 SER 326 314 314 SER SER A . n 
A 1 327 TYR 327 315 315 TYR TYR A . n 
A 1 328 ASN 328 316 316 ASN ASN A . n 
A 1 329 LYS 329 317 317 LYS LYS A . n 
A 1 330 TYR 330 318 318 TYR TYR A . n 
A 1 331 LYS 331 319 319 LYS LYS A . n 
A 1 332 TYR 332 320 320 TYR TYR A . n 
A 1 333 ASN 333 321 321 ASN ASN A . n 
A 1 334 SER 334 322 322 SER SER A . n 
A 1 335 TYR 335 323 323 TYR TYR A . n 
A 1 336 ARG 336 324 324 ARG ARG A . n 
A 1 337 ASP 337 325 325 ASP ASP A . n 
A 1 338 CYS 338 326 326 CYS CYS A . n 
A 1 339 MET 339 327 327 MET MET A . n 
A 1 340 LEU 340 328 328 LEU LEU A . n 
A 1 341 LEU 341 329 329 LEU LEU A . n 
A 1 342 GLY 342 330 330 GLY GLY A . n 
A 1 343 CYS 343 331 331 CYS CYS A . n 
A 1 344 LEU 344 332 332 LEU LEU A . n 
A 1 345 ASN 345 333 333 ASN ASN A . n 
A 1 346 SER 346 334 334 SER SER A . n 
A 1 347 GLY 347 335 335 GLY GLY A . n 
A 1 348 THR 348 336 336 THR THR A . n 
A 1 349 SER 349 337 337 SER SER A . n 
A 1 350 PHE 350 338 338 PHE PHE A . n 
A 1 351 VAL 351 339 339 VAL VAL A . n 
A 1 352 SER 352 340 340 SER SER A . n 
A 1 353 GLY 353 341 341 GLY GLY A . n 
A 1 354 PHE 354 342 342 PHE PHE A . n 
A 1 355 ALA 355 343 343 ALA ALA A . n 
A 1 356 ILE 356 344 344 ILE ILE A . n 
A 1 357 PHE 357 345 345 PHE PHE A . n 
A 1 358 SER 358 346 346 SER SER A . n 
A 1 359 ILE 359 347 347 ILE ILE A . n 
A 1 360 LEU 360 348 348 LEU LEU A . n 
A 1 361 GLY 361 349 349 GLY GLY A . n 
A 1 362 PHE 362 350 350 PHE PHE A . n 
A 1 363 MET 363 351 351 MET MET A . n 
A 1 364 ALA 364 352 352 ALA ALA A . n 
A 1 365 GLN 365 353 353 GLN GLN A . n 
A 1 366 GLU 366 354 354 GLU GLU A . n 
A 1 367 GLN 367 355 355 GLN GLN A . n 
A 1 368 GLY 368 356 356 GLY GLY A . n 
A 1 369 VAL 369 357 357 VAL VAL A . n 
A 1 370 ASP 370 358 358 ASP ASP A . n 
A 1 371 ILE 371 359 359 ILE ILE A . n 
A 1 372 ALA 372 360 360 ALA ALA A . n 
A 1 373 ASP 373 361 361 ASP ASP A . n 
A 1 374 VAL 374 362 362 VAL VAL A . n 
A 1 375 ALA 375 363 363 ALA ALA A . n 
A 1 376 GLU 376 364 364 GLU GLU A . n 
A 1 377 SER 377 365 365 SER SER A . n 
A 1 378 GLY 378 366 366 GLY GLY A . n 
A 1 379 PRO 379 367 367 PRO PRO A . n 
A 1 380 GLY 380 368 368 GLY GLY A . n 
A 1 381 LEU 381 369 369 LEU LEU A . n 
A 1 382 ALA 382 370 370 ALA ALA A . n 
A 1 383 PHE 383 371 371 PHE PHE A . n 
A 1 384 ILE 384 372 372 ILE ILE A . n 
A 1 385 ALA 385 373 373 ALA ALA A . n 
A 1 386 TYR 386 374 374 TYR TYR A . n 
A 1 387 PRO 387 375 375 PRO PRO A . n 
A 1 388 LYS 388 376 376 LYS LYS A . n 
A 1 389 ALA 389 377 377 ALA ALA A . n 
A 1 390 VAL 390 378 378 VAL VAL A . n 
A 1 391 THR 391 379 379 THR THR A . n 
A 1 392 MET 392 380 380 MET MET A . n 
A 1 393 MET 393 381 381 MET MET A . n 
A 1 394 PRO 394 382 382 PRO PRO A . n 
A 1 395 LEU 395 383 383 LEU LEU A . n 
A 1 396 PRO 396 384 384 PRO PRO A . n 
A 1 397 THR 397 385 385 THR THR A . n 
A 1 398 PHE 398 386 386 PHE PHE A . n 
A 1 399 TRP 399 387 387 TRP TRP A . n 
A 1 400 SER 400 388 388 SER SER A . n 
A 1 401 ILE 401 389 389 ILE ILE A . n 
A 1 402 LEU 402 390 390 LEU LEU A . n 
A 1 403 PHE 403 391 391 PHE PHE A . n 
A 1 404 PHE 404 392 392 PHE PHE A . n 
A 1 405 ILE 405 393 393 ILE ILE A . n 
A 1 406 MET 406 394 394 MET MET A . n 
A 1 407 LEU 407 395 395 LEU LEU A . n 
A 1 408 LEU 408 396 396 LEU LEU A . n 
A 1 409 LEU 409 397 397 LEU LEU A . n 
A 1 410 LEU 410 398 398 LEU LEU A . n 
A 1 411 GLY 411 399 399 GLY GLY A . n 
A 1 412 LEU 412 400 400 LEU LEU A . n 
A 1 413 ASP 413 401 401 ASP ASP A . n 
A 1 414 SER 414 402 402 SER SER A . n 
A 1 415 GLN 415 403 403 GLN GLN A . n 
A 1 416 PHE 416 404 404 PHE PHE A . n 
A 1 417 VAL 417 405 405 VAL VAL A . n 
A 1 418 GLU 418 406 406 GLU GLU A . n 
A 1 419 VAL 419 407 407 VAL VAL A . n 
A 1 420 GLU 420 408 408 GLU GLU A . n 
A 1 421 GLY 421 409 409 GLY GLY A . n 
A 1 422 GLN 422 410 410 GLN GLN A . n 
A 1 423 ILE 423 411 411 ILE ILE A . n 
A 1 424 THR 424 412 412 THR THR A . n 
A 1 425 SER 425 413 413 SER SER A . n 
A 1 426 LEU 426 414 414 LEU LEU A . n 
A 1 427 VAL 427 415 415 VAL VAL A . n 
A 1 428 ASP 428 416 416 ASP ASP A . n 
A 1 429 LEU 429 417 417 LEU LEU A . n 
A 1 430 TYR 430 418 418 TYR TYR A . n 
A 1 431 PRO 431 419 419 PRO PRO A . n 
A 1 432 SER 432 420 420 SER SER A . n 
A 1 433 PHE 433 421 421 PHE PHE A . n 
A 1 434 LEU 434 422 422 LEU LEU A . n 
A 1 435 ARG 435 423 423 ARG ARG A . n 
A 1 436 LYS 436 424 424 LYS LYS A . n 
A 1 437 GLY 437 425 425 GLY GLY A . n 
A 1 438 TYR 438 426 426 TYR TYR A . n 
A 1 439 ARG 439 427 427 ARG ARG A . n 
A 1 440 ARG 440 428 428 ARG ARG A . n 
A 1 441 GLU 441 429 429 GLU GLU A . n 
A 1 442 ILE 442 430 430 ILE ILE A . n 
A 1 443 PHE 443 431 431 PHE PHE A . n 
A 1 444 ILE 444 432 432 ILE ILE A . n 
A 1 445 ALA 445 433 433 ALA ALA A . n 
A 1 446 PHE 446 434 434 PHE PHE A . n 
A 1 447 VAL 447 435 435 VAL VAL A . n 
A 1 448 CYS 448 436 436 CYS CYS A . n 
A 1 449 SER 449 437 437 SER SER A . n 
A 1 450 ILE 450 438 438 ILE ILE A . n 
A 1 451 SER 451 439 439 SER SER A . n 
A 1 452 TYR 452 440 440 TYR TYR A . n 
A 1 453 LEU 453 441 441 LEU LEU A . n 
A 1 454 LEU 454 442 442 LEU LEU A . n 
A 1 455 GLY 455 443 443 GLY GLY A . n 
A 1 456 LEU 456 444 444 LEU LEU A . n 
A 1 457 THR 457 445 445 THR THR A . n 
A 1 458 MET 458 446 446 MET MET A . n 
A 1 459 VAL 459 447 447 VAL VAL A . n 
A 1 460 THR 460 448 448 THR THR A . n 
A 1 461 GLU 461 449 449 GLU GLU A . n 
A 1 462 GLY 462 450 450 GLY GLY A . n 
A 1 463 GLY 463 451 451 GLY GLY A . n 
A 1 464 MET 464 452 452 MET MET A . n 
A 1 465 TYR 465 453 453 TYR TYR A . n 
A 1 466 VAL 466 454 454 VAL VAL A . n 
A 1 467 PHE 467 455 455 PHE PHE A . n 
A 1 468 GLN 468 456 456 GLN GLN A . n 
A 1 469 LEU 469 457 457 LEU LEU A . n 
A 1 470 PHE 470 458 458 PHE PHE A . n 
A 1 471 ASP 471 459 459 ASP ASP A . n 
A 1 472 TYR 472 460 460 TYR TYR A . n 
A 1 473 TYR 473 461 461 TYR TYR A . n 
A 1 474 ALA 474 462 462 ALA ALA A . n 
A 1 475 ALA 475 463 463 ALA ALA A . n 
A 1 476 SER 476 464 464 SER SER A . n 
A 1 477 GLY 477 465 465 GLY GLY A . n 
A 1 478 VAL 478 466 466 VAL VAL A . n 
A 1 479 CYS 479 467 467 CYS CYS A . n 
A 1 480 LEU 480 468 468 LEU LEU A . n 
A 1 481 LEU 481 469 469 LEU LEU A . n 
A 1 482 TRP 482 470 470 TRP TRP A . n 
A 1 483 VAL 483 471 471 VAL VAL A . n 
A 1 484 ALA 484 472 472 ALA ALA A . n 
A 1 485 PHE 485 473 473 PHE PHE A . n 
A 1 486 PHE 486 474 474 PHE PHE A . n 
A 1 487 GLU 487 475 475 GLU GLU A . n 
A 1 488 CYS 488 476 476 CYS CYS A . n 
A 1 489 PHE 489 477 477 PHE PHE A . n 
A 1 490 VAL 490 478 478 VAL VAL A . n 
A 1 491 ILE 491 479 479 ILE ILE A . n 
A 1 492 ALA 492 480 480 ALA ALA A . n 
A 1 493 TRP 493 481 481 TRP TRP A . n 
A 1 494 ILE 494 482 482 ILE ILE A . n 
A 1 495 TYR 495 483 483 TYR TYR A . n 
A 1 496 GLY 496 484 484 GLY GLY A . n 
A 1 497 GLY 497 485 485 GLY GLY A . n 
A 1 498 ASP 498 486 486 ASP ASP A . n 
A 1 499 ASN 499 487 487 ASN ASN A . n 
A 1 500 LEU 500 488 488 LEU LEU A . n 
A 1 501 TYR 501 489 489 TYR TYR A . n 
A 1 502 ASP 502 490 490 ASP ASP A . n 
A 1 503 GLY 503 491 491 GLY GLY A . n 
A 1 504 ILE 504 492 492 ILE ILE A . n 
A 1 505 GLU 505 493 493 GLU GLU A . n 
A 1 506 ASP 506 494 494 ASP ASP A . n 
A 1 507 MET 507 495 495 MET MET A . n 
A 1 508 ILE 508 496 496 ILE ILE A . n 
A 1 509 GLY 509 497 497 GLY GLY A . n 
A 1 510 TYR 510 498 498 TYR TYR A . n 
A 1 511 ARG 511 499 499 ARG ARG A . n 
A 1 512 PRO 512 500 500 PRO PRO A . n 
A 1 513 GLY 513 501 501 GLY GLY A . n 
A 1 514 PRO 514 502 502 PRO PRO A . n 
A 1 515 TRP 515 503 503 TRP TRP A . n 
A 1 516 MET 516 504 504 MET MET A . n 
A 1 517 LYS 517 505 505 LYS LYS A . n 
A 1 518 TYR 518 506 506 TYR TYR A . n 
A 1 519 SER 519 507 507 SER SER A . n 
A 1 520 TRP 520 508 508 TRP TRP A . n 
A 1 521 ALA 521 509 509 ALA ALA A . n 
A 1 522 VAL 522 510 510 VAL VAL A . n 
A 1 523 ILE 523 511 511 ILE ILE A . n 
A 1 524 THR 524 512 512 THR THR A . n 
A 1 525 PRO 525 513 513 PRO PRO A . n 
A 1 526 VAL 526 514 514 VAL VAL A . n 
A 1 527 LEU 527 515 515 LEU LEU A . n 
A 1 528 CYS 528 516 516 CYS CYS A . n 
A 1 529 VAL 529 517 517 VAL VAL A . n 
A 1 530 GLY 530 518 518 GLY GLY A . n 
A 1 531 CYS 531 519 519 CYS CYS A . n 
A 1 532 PHE 532 520 520 PHE PHE A . n 
A 1 533 ILE 533 521 521 ILE ILE A . n 
A 1 534 PHE 534 522 522 PHE PHE A . n 
A 1 535 SER 535 523 523 SER SER A . n 
A 1 536 LEU 536 524 524 LEU LEU A . n 
A 1 537 VAL 537 525 525 VAL VAL A . n 
A 1 538 LYS 538 526 526 LYS LYS A . n 
A 1 539 TYR 539 527 527 TYR TYR A . n 
A 1 540 VAL 540 528 528 VAL VAL A . n 
A 1 541 PRO 541 529 529 PRO PRO A . n 
A 1 542 LEU 542 530 530 LEU LEU A . n 
A 1 543 THR 543 531 531 THR THR A . n 
A 1 544 TYR 544 532 532 TYR TYR A . n 
A 1 545 ASN 545 533 533 ASN ASN A . n 
A 1 546 LYS 546 534 534 LYS LYS A . n 
A 1 547 THR 547 535 535 THR THR A . n 
A 1 548 TYR 548 536 536 TYR TYR A . n 
A 1 549 VAL 549 537 537 VAL VAL A . n 
A 1 550 TYR 550 538 538 TYR TYR A . n 
A 1 551 PRO 551 539 539 PRO PRO A . n 
A 1 552 ASN 552 540 540 ASN ASN A . n 
A 1 553 TRP 553 541 541 TRP TRP A . n 
A 1 554 ALA 554 542 542 ALA ALA A . n 
A 1 555 ILE 555 543 543 ILE ILE A . n 
A 1 556 GLY 556 544 544 GLY GLY A . n 
A 1 557 LEU 557 545 545 LEU LEU A . n 
A 1 558 GLY 558 546 546 GLY GLY A . n 
A 1 559 TRP 559 547 547 TRP TRP A . n 
A 1 560 SER 560 548 548 SER SER A . n 
A 1 561 LEU 561 549 549 LEU LEU A . n 
A 1 562 ALA 562 550 550 ALA ALA A . n 
A 1 563 LEU 563 551 551 LEU LEU A . n 
A 1 564 SER 564 552 552 SER SER A . n 
A 1 565 SER 565 553 553 SER SER A . n 
A 1 566 MET 566 554 554 MET MET A . n 
A 1 567 LEU 567 555 555 LEU LEU A . n 
A 1 568 CYS 568 556 556 CYS CYS A . n 
A 1 569 VAL 569 557 557 VAL VAL A . n 
A 1 570 PRO 570 558 558 PRO PRO A . n 
A 1 571 LEU 571 559 559 LEU LEU A . n 
A 1 572 VAL 572 560 560 VAL VAL A . n 
A 1 573 ILE 573 561 561 ILE ILE A . n 
A 1 574 VAL 574 562 562 VAL VAL A . n 
A 1 575 ILE 575 563 563 ILE ILE A . n 
A 1 576 ARG 576 564 564 ARG ARG A . n 
A 1 577 LEU 577 565 565 LEU LEU A . n 
A 1 578 CYS 578 566 566 CYS CYS A . n 
A 1 579 GLN 579 567 567 GLN GLN A . n 
A 1 580 THR 580 568 568 THR THR A . n 
A 1 581 GLU 581 569 569 GLU GLU A . n 
A 1 582 GLY 582 570 570 GLY GLY A . n 
A 1 583 PRO 583 571 571 PRO PRO A . n 
A 1 584 PHE 584 572 572 PHE PHE A . n 
A 1 585 LEU 585 573 573 LEU LEU A . n 
A 1 586 VAL 586 574 574 VAL VAL A . n 
A 1 587 ARG 587 575 575 ARG ARG A . n 
A 1 588 VAL 588 576 576 VAL VAL A . n 
A 1 589 LYS 589 577 577 LYS LYS A . n 
A 1 590 TYR 590 578 578 TYR TYR A . n 
A 1 591 LEU 591 579 579 LEU LEU A . n 
A 1 592 LEU 592 580 580 LEU LEU A . n 
A 1 593 THR 593 581 581 THR THR A . n 
A 1 594 PRO 594 582 582 PRO PRO A . n 
A 1 595 ARG 595 583 583 ARG ARG A . n 
A 1 596 GLU 596 584 584 GLU GLU A . n 
A 1 597 PRO 597 585 585 PRO PRO A . n 
A 1 598 ASN 598 586 586 ASN ASN A . n 
A 1 599 ARG 599 587 587 ARG ARG A . n 
A 1 600 TRP 600 588 588 TRP TRP A . n 
A 1 601 ALA 601 589 ?   ?   ?   A . n 
A 1 602 VAL 602 590 ?   ?   ?   A . n 
A 1 603 GLU 603 591 ?   ?   ?   A . n 
A 1 604 ARG 604 592 ?   ?   ?   A . n 
A 1 605 GLU 605 593 ?   ?   ?   A . n 
A 1 606 GLY 606 594 ?   ?   ?   A . n 
A 1 607 ALA 607 595 ?   ?   ?   A . n 
A 1 608 THR 608 596 ?   ?   ?   A . n 
A 1 609 PRO 609 597 ?   ?   ?   A . n 
A 1 610 TYR 610 598 ?   ?   ?   A . n 
A 1 611 ASN 611 599 ?   ?   ?   A . n 
A 1 612 SER 612 600 ?   ?   ?   A . n 
A 1 613 ARG 613 601 ?   ?   ?   A . n 
A 1 614 THR 614 602 ?   ?   ?   A . n 
A 1 615 VAL 615 603 ?   ?   ?   A . n 
A 1 616 MET 616 604 ?   ?   ?   A . n 
A 1 617 ASN 617 605 ?   ?   ?   A . n 
A 1 618 GLY 618 606 ?   ?   ?   A . n 
A 1 619 ALA 619 607 ?   ?   ?   A . n 
A 1 620 LEU 620 608 ?   ?   ?   A . n 
A 1 621 VAL 621 609 ?   ?   ?   A . n 
A 1 622 LYS 622 610 ?   ?   ?   A . n 
A 1 623 PRO 623 611 ?   ?   ?   A . n 
A 1 624 THR 624 612 ?   ?   ?   A . n 
A 1 625 HIS 625 613 ?   ?   ?   A . n 
A 1 626 ILE 626 614 ?   ?   ?   A . n 
A 1 627 ILE 627 615 ?   ?   ?   A . n 
A 1 628 VAL 628 616 ?   ?   ?   A . n 
A 1 629 GLU 629 617 ?   ?   ?   A . n 
A 1 630 THR 630 618 ?   ?   ?   A . n 
A 1 631 MET 631 619 ?   ?   ?   A . n 
A 1 632 MET 632 620 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        TAU 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   TAU 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 TAU 1  701 602  TAU LIG A . 
C 2 TAU 1  702 603  TAU LIG A . 
D 2 TAU 1  703 604  TAU LIG A . 
E 2 TAU 1  704 605  TAU LIG A . 
F 3 NA  1  705 801  NA  NA  A . 
G 4 CL  1  706 901  CL  CL  A . 
H 5 CLR 1  707 1029 CLR CLR A . 
I 5 CLR 1  708 1030 CLR CLR A . 
J 5 CLR 1  709 1031 CLR CLR A . 
K 5 CLR 1  710 1032 CLR CLR A . 
L 5 CLR 1  711 1033 CLR CLR A . 
M 6 HOH 1  801 1028 HOH HOH A . 
M 6 HOH 2  802 1013 HOH HOH A . 
M 6 HOH 3  803 1025 HOH HOH A . 
M 6 HOH 4  804 1015 HOH HOH A . 
M 6 HOH 5  805 1009 HOH HOH A . 
M 6 HOH 6  806 1012 HOH HOH A . 
M 6 HOH 7  807 1021 HOH HOH A . 
M 6 HOH 8  808 1002 HOH HOH A . 
M 6 HOH 9  809 1026 HOH HOH A . 
M 6 HOH 10 810 1027 HOH HOH A . 
M 6 HOH 11 811 1018 HOH HOH A . 
M 6 HOH 12 812 1004 HOH HOH A . 
M 6 HOH 13 813 1014 HOH HOH A . 
M 6 HOH 14 814 1020 HOH HOH A . 
M 6 HOH 15 815 1011 HOH HOH A . 
M 6 HOH 16 816 1010 HOH HOH A . 
M 6 HOH 17 817 1024 HOH HOH A . 
M 6 HOH 18 818 1022 HOH HOH A . 
M 6 HOH 19 819 1023 HOH HOH A . 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9K7B 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9K7B 
_struct.title                        
'Cryo-EM structure of human taurine transporter TauT bound with taurine molecules in an inward-open state in the saposin-disc' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9K7B 
_struct_keywords.text            'Complex, PROTEIN TRANSPORT' 
_struct_keywords.pdbx_keywords   'PROTEIN TRANSPORT' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 2 ? 
E N N 2 ? 
F N N 3 ? 
G N N 4 ? 
H N N 5 ? 
I N N 5 ? 
J N N 5 ? 
K N N 5 ? 
L N N 5 ? 
M N N 6 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    SC6A6_HUMAN 
_struct_ref.pdbx_db_accession          P31641 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFL
IPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA
HCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVR
STGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKY
NSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGL
DSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIA
WIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLV
IVIRLCQTEGPFLVRVKYLLTPREPNRWAVEREGATPYNSRTVMNGALVKPTHIIVETMM
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9K7B 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 13 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 632 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             P31641 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  620 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       620 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9K7B MET A 1  ? UNP P31641 ? ? 'initiating methionine' -11 1  
1 9K7B ASP A 2  ? UNP P31641 ? ? 'expression tag'        -10 2  
1 9K7B TYR A 3  ? UNP P31641 ? ? 'expression tag'        -9  3  
1 9K7B LYS A 4  ? UNP P31641 ? ? 'expression tag'        -8  4  
1 9K7B ASP A 5  ? UNP P31641 ? ? 'expression tag'        -7  5  
1 9K7B ASP A 6  ? UNP P31641 ? ? 'expression tag'        -6  6  
1 9K7B ASP A 7  ? UNP P31641 ? ? 'expression tag'        -5  7  
1 9K7B ASP A 8  ? UNP P31641 ? ? 'expression tag'        -4  8  
1 9K7B LYS A 9  ? UNP P31641 ? ? 'expression tag'        -3  9  
1 9K7B GLY A 10 ? UNP P31641 ? ? 'expression tag'        -2  10 
1 9K7B SER A 11 ? UNP P31641 ? ? 'expression tag'        -1  11 
1 9K7B GLY A 12 ? UNP P31641 ? ? 'expression tag'        0   12 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 58  ? ALA A 67  ? SER A 46  ALA A 55  1 ? 10 
HELX_P HELX_P2  AA2 GLY A 72  ? TRP A 77  ? GLY A 60  TRP A 65  1 ? 6  
HELX_P HELX_P3  AA3 TRP A 77  ? ASN A 86  ? TRP A 65  ASN A 74  1 ? 10 
HELX_P HELX_P4  AA4 GLY A 87  ? SER A 102 ? GLY A 75  SER A 90  1 ? 16 
HELX_P HELX_P5  AA5 SER A 102 ? SER A 118 ? SER A 90  SER A 106 1 ? 17 
HELX_P HELX_P6  AA6 GLY A 120 ? CYS A 129 ? GLY A 108 CYS A 117 1 ? 10 
HELX_P HELX_P7  AA7 PRO A 130 ? PHE A 132 ? PRO A 118 PHE A 120 5 ? 3  
HELX_P HELX_P8  AA8 SER A 133 ? PHE A 165 ? SER A 121 PHE A 153 1 ? 33 
HELX_P HELX_P9  AA9 LEU A 169 ? HIS A 173 ? LEU A 157 HIS A 161 5 ? 5  
HELX_P HELX_P10 AB1 GLU A 185 ? ASN A 191 ? GLU A 173 ASN A 179 1 ? 7  
HELX_P HELX_P11 AB2 SER A 205 ? ARG A 213 ? SER A 193 ARG A 201 1 ? 9  
HELX_P HELX_P12 AB3 LYS A 229 ? GLY A 250 ? LYS A 217 GLY A 238 1 ? 22 
HELX_P HELX_P13 AB4 VAL A 257 ? THR A 278 ? VAL A 245 THR A 266 1 ? 22 
HELX_P HELX_P14 AB5 GLY A 281 ? TYR A 291 ? GLY A 269 TYR A 279 1 ? 11 
HELX_P HELX_P15 AB6 ASP A 293 ? GLU A 298 ? ASP A 281 GLU A 286 1 ? 6  
HELX_P HELX_P16 AB7 ASP A 299 ? ALA A 315 ? ASP A 287 ALA A 303 1 ? 17 
HELX_P HELX_P17 AB8 GLY A 319 ? ASN A 328 ? GLY A 307 ASN A 316 1 ? 10 
HELX_P HELX_P18 AB9 ASN A 333 ? GLY A 368 ? ASN A 321 GLY A 356 1 ? 36 
HELX_P HELX_P19 AC1 ASP A 370 ? ALA A 375 ? ASP A 358 ALA A 363 1 ? 6  
HELX_P HELX_P20 AC2 LEU A 381 ? MET A 393 ? LEU A 369 MET A 381 1 ? 13 
HELX_P HELX_P21 AC3 LEU A 395 ? TYR A 430 ? LEU A 383 TYR A 418 1 ? 36 
HELX_P HELX_P22 AC4 TYR A 430 ? ARG A 435 ? TYR A 418 ARG A 423 1 ? 6  
HELX_P HELX_P23 AC5 LYS A 436 ? VAL A 459 ? LYS A 424 VAL A 447 1 ? 24 
HELX_P HELX_P24 AC6 GLY A 462 ? ALA A 474 ? GLY A 450 ALA A 462 1 ? 13 
HELX_P HELX_P25 AC7 GLY A 477 ? ILE A 494 ? GLY A 465 ILE A 482 1 ? 18 
HELX_P HELX_P26 AC8 GLY A 496 ? GLY A 509 ? GLY A 484 GLY A 497 1 ? 14 
HELX_P HELX_P27 AC9 PRO A 514 ? VAL A 522 ? PRO A 502 VAL A 510 1 ? 9  
HELX_P HELX_P28 AD1 VAL A 522 ? LYS A 538 ? VAL A 510 LYS A 526 1 ? 17 
HELX_P HELX_P29 AD2 ASN A 545 ? THR A 547 ? ASN A 533 THR A 535 5 ? 3  
HELX_P HELX_P30 AD3 PRO A 551 ? THR A 580 ? PRO A 539 THR A 568 1 ? 30 
HELX_P HELX_P31 AD4 PRO A 583 ? THR A 593 ? PRO A 571 THR A 581 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 174 SG ? ? ? 1_555 A CYS 183 SG ? ? A CYS 162 A CYS 171 1_555 ? ? ? ? ? ? ? 2.027 ? ? 
metalc1 metalc ? ? A TYR 150 OH ? ? ? 1_555 F NA  .   NA ? ? A TYR 138 A NA  705 1_555 ? ? ? ? ? ? ? 2.362 ? ? 
metalc2 metalc ? ? A SER 414 OG ? ? ? 1_555 F NA  .   NA ? ? A SER 402 A NA  705 1_555 ? ? ? ? ? ? ? 2.797 ? ? 
metalc3 metalc ? ? E TAU .   O2 ? ? ? 1_555 F NA  .   NA ? ? A TAU 704 A NA  705 1_555 ? ? ? ? ? ? ? 2.903 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1 OH ? A TYR 150 ? A TYR 138 ? 1_555 NA ? F NA . ? A NA 705 ? 1_555 OG ? A SER 414 ? A SER 402 ? 1_555 87.9 ? 
2 OH ? A TYR 150 ? A TYR 138 ? 1_555 NA ? F NA . ? A NA 705 ? 1_555 O2 ? E TAU .   ? A TAU 704 ? 1_555 90.3 ? 
3 OG ? A SER 414 ? A SER 402 ? 1_555 NA ? F NA . ? A NA 705 ? 1_555 O2 ? E TAU .   ? A TAU 704 ? 1_555 77.1 ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      CYS 
_pdbx_modification_feature.label_asym_id                      A 
_pdbx_modification_feature.label_seq_id                       174 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     A 
_pdbx_modification_feature.modified_residue_label_seq_id      183 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       CYS 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        162 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      A 
_pdbx_modification_feature.modified_residue_auth_seq_id       171 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               SG 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                . 
_pdbx_modification_feature.ref_pcm_id                         . 
_pdbx_modification_feature.ref_comp_id                        . 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Disulfide bridge' 
# 
_struct_sheet.id               AA1 
_struct_sheet.type             ? 
_struct_sheet.number_strands   2 
_struct_sheet.details          ? 
# 
_struct_sheet_order.sheet_id     AA1 
_struct_sheet_order.range_id_1   1 
_struct_sheet_order.range_id_2   2 
_struct_sheet_order.offset       ? 
_struct_sheet_order.sense        anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 THR A 543 ? TYR A 544 ? THR A 531 TYR A 532 
AA1 2 TYR A 548 ? VAL A 549 ? TYR A 536 VAL A 537 
# 
_pdbx_struct_sheet_hbond.sheet_id                AA1 
_pdbx_struct_sheet_hbond.range_id_1              1 
_pdbx_struct_sheet_hbond.range_id_2              2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id   N 
_pdbx_struct_sheet_hbond.range_1_label_comp_id   TYR 
_pdbx_struct_sheet_hbond.range_1_label_asym_id   A 
_pdbx_struct_sheet_hbond.range_1_label_seq_id    544 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id    N 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id    TYR 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id    A 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id     532 
_pdbx_struct_sheet_hbond.range_2_label_atom_id   O 
_pdbx_struct_sheet_hbond.range_2_label_comp_id   TYR 
_pdbx_struct_sheet_hbond.range_2_label_asym_id   A 
_pdbx_struct_sheet_hbond.range_2_label_seq_id    548 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id    O 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id    TYR 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id    A 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id     536 
# 
_pdbx_entry_details.entry_id                   9K7B 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O   A PHE 392 ? ? CD1 A LEU 396 ? ? 1.78 
2 1 NH1 A ARG 66  ? ? OD1 A ASP 459 ? ? 2.03 
3 1 CD2 A LEU 226 ? ? C24 A CLR 711 ? ? 2.15 
4 1 N1  A TAU 703 ? ? O1  A TAU 704 ? ? 2.17 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ILE A 184 ? ? -105.14 -70.63 
2 1 ILE A 482 ? ? -98.16  -62.15 
3 1 VAL A 510 ? ? -122.17 -54.72 
4 1 LYS A 526 ? ? -109.82 77.67  
5 1 LYS A 534 ? ? 75.62   -4.02  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9K7B 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9K7B 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.75 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               129662 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Sodium- and chloride-dependent taurine transporter' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9K7B 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'SPOT SCAN' 
_em_imaging.mode                            DIFFRACTION 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             3000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9K7B 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9K7B 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET -11 ? A MET 1   
2  1 Y 1 A ASP -10 ? A ASP 2   
3  1 Y 1 A TYR -9  ? A TYR 3   
4  1 Y 1 A LYS -8  ? A LYS 4   
5  1 Y 1 A ASP -7  ? A ASP 5   
6  1 Y 1 A ASP -6  ? A ASP 6   
7  1 Y 1 A ASP -5  ? A ASP 7   
8  1 Y 1 A ASP -4  ? A ASP 8   
9  1 Y 1 A LYS -3  ? A LYS 9   
10 1 Y 1 A GLY -2  ? A GLY 10  
11 1 Y 1 A SER -1  ? A SER 11  
12 1 Y 1 A GLY 0   ? A GLY 12  
13 1 Y 1 A MET 1   ? A MET 13  
14 1 Y 1 A ALA 2   ? A ALA 14  
15 1 Y 1 A THR 3   ? A THR 15  
16 1 Y 1 A LYS 4   ? A LYS 16  
17 1 Y 1 A GLU 5   ? A GLU 17  
18 1 Y 1 A LYS 6   ? A LYS 18  
19 1 Y 1 A LEU 7   ? A LEU 19  
20 1 Y 1 A GLN 8   ? A GLN 20  
21 1 Y 1 A CYS 9   ? A CYS 21  
22 1 Y 1 A LEU 10  ? A LEU 22  
23 1 Y 1 A LYS 11  ? A LYS 23  
24 1 Y 1 A ASP 12  ? A ASP 24  
25 1 Y 1 A PHE 13  ? A PHE 25  
26 1 Y 1 A HIS 14  ? A HIS 26  
27 1 Y 1 A LYS 15  ? A LYS 27  
28 1 Y 1 A ASP 16  ? A ASP 28  
29 1 Y 1 A ILE 17  ? A ILE 29  
30 1 Y 1 A LEU 18  ? A LEU 30  
31 1 Y 1 A LYS 19  ? A LYS 31  
32 1 Y 1 A PRO 20  ? A PRO 32  
33 1 Y 1 A SER 21  ? A SER 33  
34 1 Y 1 A PRO 22  ? A PRO 34  
35 1 Y 1 A GLY 23  ? A GLY 35  
36 1 Y 1 A LYS 24  ? A LYS 36  
37 1 Y 1 A SER 25  ? A SER 37  
38 1 Y 1 A PRO 26  ? A PRO 38  
39 1 Y 1 A GLY 27  ? A GLY 39  
40 1 Y 1 A THR 28  ? A THR 40  
41 1 Y 1 A ARG 29  ? A ARG 41  
42 1 Y 1 A PRO 30  ? A PRO 42  
43 1 Y 1 A GLU 31  ? A GLU 43  
44 1 Y 1 A ASP 32  ? A ASP 44  
45 1 Y 1 A GLU 33  ? A GLU 45  
46 1 Y 1 A ALA 34  ? A ALA 46  
47 1 Y 1 A GLU 35  ? A GLU 47  
48 1 Y 1 A GLY 36  ? A GLY 48  
49 1 Y 1 A LYS 37  ? A LYS 49  
50 1 Y 1 A PRO 38  ? A PRO 50  
51 1 Y 1 A PRO 39  ? A PRO 51  
52 1 Y 1 A GLN 40  ? A GLN 52  
53 1 Y 1 A ARG 41  ? A ARG 53  
54 1 Y 1 A GLU 42  ? A GLU 54  
55 1 Y 1 A LYS 43  ? A LYS 55  
56 1 Y 1 A TRP 44  ? A TRP 56  
57 1 Y 1 A ALA 589 ? A ALA 601 
58 1 Y 1 A VAL 590 ? A VAL 602 
59 1 Y 1 A GLU 591 ? A GLU 603 
60 1 Y 1 A ARG 592 ? A ARG 604 
61 1 Y 1 A GLU 593 ? A GLU 605 
62 1 Y 1 A GLY 594 ? A GLY 606 
63 1 Y 1 A ALA 595 ? A ALA 607 
64 1 Y 1 A THR 596 ? A THR 608 
65 1 Y 1 A PRO 597 ? A PRO 609 
66 1 Y 1 A TYR 598 ? A TYR 610 
67 1 Y 1 A ASN 599 ? A ASN 611 
68 1 Y 1 A SER 600 ? A SER 612 
69 1 Y 1 A ARG 601 ? A ARG 613 
70 1 Y 1 A THR 602 ? A THR 614 
71 1 Y 1 A VAL 603 ? A VAL 615 
72 1 Y 1 A MET 604 ? A MET 616 
73 1 Y 1 A ASN 605 ? A ASN 617 
74 1 Y 1 A GLY 606 ? A GLY 618 
75 1 Y 1 A ALA 607 ? A ALA 619 
76 1 Y 1 A LEU 608 ? A LEU 620 
77 1 Y 1 A VAL 609 ? A VAL 621 
78 1 Y 1 A LYS 610 ? A LYS 622 
79 1 Y 1 A PRO 611 ? A PRO 623 
80 1 Y 1 A THR 612 ? A THR 624 
81 1 Y 1 A HIS 613 ? A HIS 625 
82 1 Y 1 A ILE 614 ? A ILE 626 
83 1 Y 1 A ILE 615 ? A ILE 627 
84 1 Y 1 A VAL 616 ? A VAL 628 
85 1 Y 1 A GLU 617 ? A GLU 629 
86 1 Y 1 A THR 618 ? A THR 630 
87 1 Y 1 A MET 619 ? A MET 631 
88 1 Y 1 A MET 620 ? A MET 632 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CL  CL   CL N N 74  
CLR C1   C  N N 75  
CLR C2   C  N N 76  
CLR C3   C  N S 77  
CLR C4   C  N N 78  
CLR C5   C  N N 79  
CLR C6   C  N N 80  
CLR C7   C  N N 81  
CLR C8   C  N S 82  
CLR C9   C  N S 83  
CLR C10  C  N R 84  
CLR C11  C  N N 85  
CLR C12  C  N N 86  
CLR C13  C  N R 87  
CLR C14  C  N S 88  
CLR C15  C  N N 89  
CLR C16  C  N N 90  
CLR C17  C  N R 91  
CLR C18  C  N N 92  
CLR C19  C  N N 93  
CLR C20  C  N R 94  
CLR C21  C  N N 95  
CLR C22  C  N N 96  
CLR C23  C  N N 97  
CLR C24  C  N N 98  
CLR C25  C  N N 99  
CLR C26  C  N N 100 
CLR C27  C  N N 101 
CLR O1   O  N N 102 
CLR H11  H  N N 103 
CLR H12  H  N N 104 
CLR H21  H  N N 105 
CLR H22  H  N N 106 
CLR H3   H  N N 107 
CLR H41  H  N N 108 
CLR H42  H  N N 109 
CLR H6   H  N N 110 
CLR H71  H  N N 111 
CLR H72  H  N N 112 
CLR H8   H  N N 113 
CLR H9   H  N N 114 
CLR H111 H  N N 115 
CLR H112 H  N N 116 
CLR H121 H  N N 117 
CLR H122 H  N N 118 
CLR H14  H  N N 119 
CLR H151 H  N N 120 
CLR H152 H  N N 121 
CLR H161 H  N N 122 
CLR H162 H  N N 123 
CLR H17  H  N N 124 
CLR H181 H  N N 125 
CLR H182 H  N N 126 
CLR H183 H  N N 127 
CLR H191 H  N N 128 
CLR H192 H  N N 129 
CLR H193 H  N N 130 
CLR H20  H  N N 131 
CLR H211 H  N N 132 
CLR H212 H  N N 133 
CLR H213 H  N N 134 
CLR H221 H  N N 135 
CLR H222 H  N N 136 
CLR H231 H  N N 137 
CLR H232 H  N N 138 
CLR H241 H  N N 139 
CLR H242 H  N N 140 
CLR H25  H  N N 141 
CLR H261 H  N N 142 
CLR H262 H  N N 143 
CLR H263 H  N N 144 
CLR H271 H  N N 145 
CLR H272 H  N N 146 
CLR H273 H  N N 147 
CLR H1   H  N N 148 
CYS N    N  N N 149 
CYS CA   C  N R 150 
CYS C    C  N N 151 
CYS O    O  N N 152 
CYS CB   C  N N 153 
CYS SG   S  N N 154 
CYS OXT  O  N N 155 
CYS H    H  N N 156 
CYS H2   H  N N 157 
CYS HA   H  N N 158 
CYS HB2  H  N N 159 
CYS HB3  H  N N 160 
CYS HG   H  N N 161 
CYS HXT  H  N N 162 
GLN N    N  N N 163 
GLN CA   C  N S 164 
GLN C    C  N N 165 
GLN O    O  N N 166 
GLN CB   C  N N 167 
GLN CG   C  N N 168 
GLN CD   C  N N 169 
GLN OE1  O  N N 170 
GLN NE2  N  N N 171 
GLN OXT  O  N N 172 
GLN H    H  N N 173 
GLN H2   H  N N 174 
GLN HA   H  N N 175 
GLN HB2  H  N N 176 
GLN HB3  H  N N 177 
GLN HG2  H  N N 178 
GLN HG3  H  N N 179 
GLN HE21 H  N N 180 
GLN HE22 H  N N 181 
GLN HXT  H  N N 182 
GLU N    N  N N 183 
GLU CA   C  N S 184 
GLU C    C  N N 185 
GLU O    O  N N 186 
GLU CB   C  N N 187 
GLU CG   C  N N 188 
GLU CD   C  N N 189 
GLU OE1  O  N N 190 
GLU OE2  O  N N 191 
GLU OXT  O  N N 192 
GLU H    H  N N 193 
GLU H2   H  N N 194 
GLU HA   H  N N 195 
GLU HB2  H  N N 196 
GLU HB3  H  N N 197 
GLU HG2  H  N N 198 
GLU HG3  H  N N 199 
GLU HE2  H  N N 200 
GLU HXT  H  N N 201 
GLY N    N  N N 202 
GLY CA   C  N N 203 
GLY C    C  N N 204 
GLY O    O  N N 205 
GLY OXT  O  N N 206 
GLY H    H  N N 207 
GLY H2   H  N N 208 
GLY HA2  H  N N 209 
GLY HA3  H  N N 210 
GLY HXT  H  N N 211 
HIS N    N  N N 212 
HIS CA   C  N S 213 
HIS C    C  N N 214 
HIS O    O  N N 215 
HIS CB   C  N N 216 
HIS CG   C  Y N 217 
HIS ND1  N  Y N 218 
HIS CD2  C  Y N 219 
HIS CE1  C  Y N 220 
HIS NE2  N  Y N 221 
HIS OXT  O  N N 222 
HIS H    H  N N 223 
HIS H2   H  N N 224 
HIS HA   H  N N 225 
HIS HB2  H  N N 226 
HIS HB3  H  N N 227 
HIS HD1  H  N N 228 
HIS HD2  H  N N 229 
HIS HE1  H  N N 230 
HIS HE2  H  N N 231 
HIS HXT  H  N N 232 
HOH O    O  N N 233 
HOH H1   H  N N 234 
HOH H2   H  N N 235 
ILE N    N  N N 236 
ILE CA   C  N S 237 
ILE C    C  N N 238 
ILE O    O  N N 239 
ILE CB   C  N S 240 
ILE CG1  C  N N 241 
ILE CG2  C  N N 242 
ILE CD1  C  N N 243 
ILE OXT  O  N N 244 
ILE H    H  N N 245 
ILE H2   H  N N 246 
ILE HA   H  N N 247 
ILE HB   H  N N 248 
ILE HG12 H  N N 249 
ILE HG13 H  N N 250 
ILE HG21 H  N N 251 
ILE HG22 H  N N 252 
ILE HG23 H  N N 253 
ILE HD11 H  N N 254 
ILE HD12 H  N N 255 
ILE HD13 H  N N 256 
ILE HXT  H  N N 257 
LEU N    N  N N 258 
LEU CA   C  N S 259 
LEU C    C  N N 260 
LEU O    O  N N 261 
LEU CB   C  N N 262 
LEU CG   C  N N 263 
LEU CD1  C  N N 264 
LEU CD2  C  N N 265 
LEU OXT  O  N N 266 
LEU H    H  N N 267 
LEU H2   H  N N 268 
LEU HA   H  N N 269 
LEU HB2  H  N N 270 
LEU HB3  H  N N 271 
LEU HG   H  N N 272 
LEU HD11 H  N N 273 
LEU HD12 H  N N 274 
LEU HD13 H  N N 275 
LEU HD21 H  N N 276 
LEU HD22 H  N N 277 
LEU HD23 H  N N 278 
LEU HXT  H  N N 279 
LYS N    N  N N 280 
LYS CA   C  N S 281 
LYS C    C  N N 282 
LYS O    O  N N 283 
LYS CB   C  N N 284 
LYS CG   C  N N 285 
LYS CD   C  N N 286 
LYS CE   C  N N 287 
LYS NZ   N  N N 288 
LYS OXT  O  N N 289 
LYS H    H  N N 290 
LYS H2   H  N N 291 
LYS HA   H  N N 292 
LYS HB2  H  N N 293 
LYS HB3  H  N N 294 
LYS HG2  H  N N 295 
LYS HG3  H  N N 296 
LYS HD2  H  N N 297 
LYS HD3  H  N N 298 
LYS HE2  H  N N 299 
LYS HE3  H  N N 300 
LYS HZ1  H  N N 301 
LYS HZ2  H  N N 302 
LYS HZ3  H  N N 303 
LYS HXT  H  N N 304 
MET N    N  N N 305 
MET CA   C  N S 306 
MET C    C  N N 307 
MET O    O  N N 308 
MET CB   C  N N 309 
MET CG   C  N N 310 
MET SD   S  N N 311 
MET CE   C  N N 312 
MET OXT  O  N N 313 
MET H    H  N N 314 
MET H2   H  N N 315 
MET HA   H  N N 316 
MET HB2  H  N N 317 
MET HB3  H  N N 318 
MET HG2  H  N N 319 
MET HG3  H  N N 320 
MET HE1  H  N N 321 
MET HE2  H  N N 322 
MET HE3  H  N N 323 
MET HXT  H  N N 324 
NA  NA   NA N N 325 
PHE N    N  N N 326 
PHE CA   C  N S 327 
PHE C    C  N N 328 
PHE O    O  N N 329 
PHE CB   C  N N 330 
PHE CG   C  Y N 331 
PHE CD1  C  Y N 332 
PHE CD2  C  Y N 333 
PHE CE1  C  Y N 334 
PHE CE2  C  Y N 335 
PHE CZ   C  Y N 336 
PHE OXT  O  N N 337 
PHE H    H  N N 338 
PHE H2   H  N N 339 
PHE HA   H  N N 340 
PHE HB2  H  N N 341 
PHE HB3  H  N N 342 
PHE HD1  H  N N 343 
PHE HD2  H  N N 344 
PHE HE1  H  N N 345 
PHE HE2  H  N N 346 
PHE HZ   H  N N 347 
PHE HXT  H  N N 348 
PRO N    N  N N 349 
PRO CA   C  N S 350 
PRO C    C  N N 351 
PRO O    O  N N 352 
PRO CB   C  N N 353 
PRO CG   C  N N 354 
PRO CD   C  N N 355 
PRO OXT  O  N N 356 
PRO H    H  N N 357 
PRO HA   H  N N 358 
PRO HB2  H  N N 359 
PRO HB3  H  N N 360 
PRO HG2  H  N N 361 
PRO HG3  H  N N 362 
PRO HD2  H  N N 363 
PRO HD3  H  N N 364 
PRO HXT  H  N N 365 
SER N    N  N N 366 
SER CA   C  N S 367 
SER C    C  N N 368 
SER O    O  N N 369 
SER CB   C  N N 370 
SER OG   O  N N 371 
SER OXT  O  N N 372 
SER H    H  N N 373 
SER H2   H  N N 374 
SER HA   H  N N 375 
SER HB2  H  N N 376 
SER HB3  H  N N 377 
SER HG   H  N N 378 
SER HXT  H  N N 379 
TAU C1   C  N N 380 
TAU C2   C  N N 381 
TAU N1   N  N N 382 
TAU S    S  N N 383 
TAU O1   O  N N 384 
TAU O2   O  N N 385 
TAU O3   O  N N 386 
TAU H1C1 H  N N 387 
TAU H1C2 H  N N 388 
TAU H2C1 H  N N 389 
TAU H2C2 H  N N 390 
TAU H1N1 H  N N 391 
TAU H1N2 H  N N 392 
TAU H2   H  N N 393 
THR N    N  N N 394 
THR CA   C  N S 395 
THR C    C  N N 396 
THR O    O  N N 397 
THR CB   C  N R 398 
THR OG1  O  N N 399 
THR CG2  C  N N 400 
THR OXT  O  N N 401 
THR H    H  N N 402 
THR H2   H  N N 403 
THR HA   H  N N 404 
THR HB   H  N N 405 
THR HG1  H  N N 406 
THR HG21 H  N N 407 
THR HG22 H  N N 408 
THR HG23 H  N N 409 
THR HXT  H  N N 410 
TRP N    N  N N 411 
TRP CA   C  N S 412 
TRP C    C  N N 413 
TRP O    O  N N 414 
TRP CB   C  N N 415 
TRP CG   C  Y N 416 
TRP CD1  C  Y N 417 
TRP CD2  C  Y N 418 
TRP NE1  N  Y N 419 
TRP CE2  C  Y N 420 
TRP CE3  C  Y N 421 
TRP CZ2  C  Y N 422 
TRP CZ3  C  Y N 423 
TRP CH2  C  Y N 424 
TRP OXT  O  N N 425 
TRP H    H  N N 426 
TRP H2   H  N N 427 
TRP HA   H  N N 428 
TRP HB2  H  N N 429 
TRP HB3  H  N N 430 
TRP HD1  H  N N 431 
TRP HE1  H  N N 432 
TRP HE3  H  N N 433 
TRP HZ2  H  N N 434 
TRP HZ3  H  N N 435 
TRP HH2  H  N N 436 
TRP HXT  H  N N 437 
TYR N    N  N N 438 
TYR CA   C  N S 439 
TYR C    C  N N 440 
TYR O    O  N N 441 
TYR CB   C  N N 442 
TYR CG   C  Y N 443 
TYR CD1  C  Y N 444 
TYR CD2  C  Y N 445 
TYR CE1  C  Y N 446 
TYR CE2  C  Y N 447 
TYR CZ   C  Y N 448 
TYR OH   O  N N 449 
TYR OXT  O  N N 450 
TYR H    H  N N 451 
TYR H2   H  N N 452 
TYR HA   H  N N 453 
TYR HB2  H  N N 454 
TYR HB3  H  N N 455 
TYR HD1  H  N N 456 
TYR HD2  H  N N 457 
TYR HE1  H  N N 458 
TYR HE2  H  N N 459 
TYR HH   H  N N 460 
TYR HXT  H  N N 461 
VAL N    N  N N 462 
VAL CA   C  N S 463 
VAL C    C  N N 464 
VAL O    O  N N 465 
VAL CB   C  N N 466 
VAL CG1  C  N N 467 
VAL CG2  C  N N 468 
VAL OXT  O  N N 469 
VAL H    H  N N 470 
VAL H2   H  N N 471 
VAL HA   H  N N 472 
VAL HB   H  N N 473 
VAL HG11 H  N N 474 
VAL HG12 H  N N 475 
VAL HG13 H  N N 476 
VAL HG21 H  N N 477 
VAL HG22 H  N N 478 
VAL HG23 H  N N 479 
VAL HXT  H  N N 480 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CLR C1  C2   sing N N 70  
CLR C1  C10  sing N N 71  
CLR C1  H11  sing N N 72  
CLR C1  H12  sing N N 73  
CLR C2  C3   sing N N 74  
CLR C2  H21  sing N N 75  
CLR C2  H22  sing N N 76  
CLR C3  C4   sing N N 77  
CLR C3  O1   sing N N 78  
CLR C3  H3   sing N N 79  
CLR C4  C5   sing N N 80  
CLR C4  H41  sing N N 81  
CLR C4  H42  sing N N 82  
CLR C5  C6   doub N N 83  
CLR C5  C10  sing N N 84  
CLR C6  C7   sing N N 85  
CLR C6  H6   sing N N 86  
CLR C7  C8   sing N N 87  
CLR C7  H71  sing N N 88  
CLR C7  H72  sing N N 89  
CLR C8  C9   sing N N 90  
CLR C8  C14  sing N N 91  
CLR C8  H8   sing N N 92  
CLR C9  C10  sing N N 93  
CLR C9  C11  sing N N 94  
CLR C9  H9   sing N N 95  
CLR C10 C19  sing N N 96  
CLR C11 C12  sing N N 97  
CLR C11 H111 sing N N 98  
CLR C11 H112 sing N N 99  
CLR C12 C13  sing N N 100 
CLR C12 H121 sing N N 101 
CLR C12 H122 sing N N 102 
CLR C13 C14  sing N N 103 
CLR C13 C17  sing N N 104 
CLR C13 C18  sing N N 105 
CLR C14 C15  sing N N 106 
CLR C14 H14  sing N N 107 
CLR C15 C16  sing N N 108 
CLR C15 H151 sing N N 109 
CLR C15 H152 sing N N 110 
CLR C16 C17  sing N N 111 
CLR C16 H161 sing N N 112 
CLR C16 H162 sing N N 113 
CLR C17 C20  sing N N 114 
CLR C17 H17  sing N N 115 
CLR C18 H181 sing N N 116 
CLR C18 H182 sing N N 117 
CLR C18 H183 sing N N 118 
CLR C19 H191 sing N N 119 
CLR C19 H192 sing N N 120 
CLR C19 H193 sing N N 121 
CLR C20 C21  sing N N 122 
CLR C20 C22  sing N N 123 
CLR C20 H20  sing N N 124 
CLR C21 H211 sing N N 125 
CLR C21 H212 sing N N 126 
CLR C21 H213 sing N N 127 
CLR C22 C23  sing N N 128 
CLR C22 H221 sing N N 129 
CLR C22 H222 sing N N 130 
CLR C23 C24  sing N N 131 
CLR C23 H231 sing N N 132 
CLR C23 H232 sing N N 133 
CLR C24 C25  sing N N 134 
CLR C24 H241 sing N N 135 
CLR C24 H242 sing N N 136 
CLR C25 C26  sing N N 137 
CLR C25 C27  sing N N 138 
CLR C25 H25  sing N N 139 
CLR C26 H261 sing N N 140 
CLR C26 H262 sing N N 141 
CLR C26 H263 sing N N 142 
CLR C27 H271 sing N N 143 
CLR C27 H272 sing N N 144 
CLR C27 H273 sing N N 145 
CLR O1  H1   sing N N 146 
CYS N   CA   sing N N 147 
CYS N   H    sing N N 148 
CYS N   H2   sing N N 149 
CYS CA  C    sing N N 150 
CYS CA  CB   sing N N 151 
CYS CA  HA   sing N N 152 
CYS C   O    doub N N 153 
CYS C   OXT  sing N N 154 
CYS CB  SG   sing N N 155 
CYS CB  HB2  sing N N 156 
CYS CB  HB3  sing N N 157 
CYS SG  HG   sing N N 158 
CYS OXT HXT  sing N N 159 
GLN N   CA   sing N N 160 
GLN N   H    sing N N 161 
GLN N   H2   sing N N 162 
GLN CA  C    sing N N 163 
GLN CA  CB   sing N N 164 
GLN CA  HA   sing N N 165 
GLN C   O    doub N N 166 
GLN C   OXT  sing N N 167 
GLN CB  CG   sing N N 168 
GLN CB  HB2  sing N N 169 
GLN CB  HB3  sing N N 170 
GLN CG  CD   sing N N 171 
GLN CG  HG2  sing N N 172 
GLN CG  HG3  sing N N 173 
GLN CD  OE1  doub N N 174 
GLN CD  NE2  sing N N 175 
GLN NE2 HE21 sing N N 176 
GLN NE2 HE22 sing N N 177 
GLN OXT HXT  sing N N 178 
GLU N   CA   sing N N 179 
GLU N   H    sing N N 180 
GLU N   H2   sing N N 181 
GLU CA  C    sing N N 182 
GLU CA  CB   sing N N 183 
GLU CA  HA   sing N N 184 
GLU C   O    doub N N 185 
GLU C   OXT  sing N N 186 
GLU CB  CG   sing N N 187 
GLU CB  HB2  sing N N 188 
GLU CB  HB3  sing N N 189 
GLU CG  CD   sing N N 190 
GLU CG  HG2  sing N N 191 
GLU CG  HG3  sing N N 192 
GLU CD  OE1  doub N N 193 
GLU CD  OE2  sing N N 194 
GLU OE2 HE2  sing N N 195 
GLU OXT HXT  sing N N 196 
GLY N   CA   sing N N 197 
GLY N   H    sing N N 198 
GLY N   H2   sing N N 199 
GLY CA  C    sing N N 200 
GLY CA  HA2  sing N N 201 
GLY CA  HA3  sing N N 202 
GLY C   O    doub N N 203 
GLY C   OXT  sing N N 204 
GLY OXT HXT  sing N N 205 
HIS N   CA   sing N N 206 
HIS N   H    sing N N 207 
HIS N   H2   sing N N 208 
HIS CA  C    sing N N 209 
HIS CA  CB   sing N N 210 
HIS CA  HA   sing N N 211 
HIS C   O    doub N N 212 
HIS C   OXT  sing N N 213 
HIS CB  CG   sing N N 214 
HIS CB  HB2  sing N N 215 
HIS CB  HB3  sing N N 216 
HIS CG  ND1  sing Y N 217 
HIS CG  CD2  doub Y N 218 
HIS ND1 CE1  doub Y N 219 
HIS ND1 HD1  sing N N 220 
HIS CD2 NE2  sing Y N 221 
HIS CD2 HD2  sing N N 222 
HIS CE1 NE2  sing Y N 223 
HIS CE1 HE1  sing N N 224 
HIS NE2 HE2  sing N N 225 
HIS OXT HXT  sing N N 226 
HOH O   H1   sing N N 227 
HOH O   H2   sing N N 228 
ILE N   CA   sing N N 229 
ILE N   H    sing N N 230 
ILE N   H2   sing N N 231 
ILE CA  C    sing N N 232 
ILE CA  CB   sing N N 233 
ILE CA  HA   sing N N 234 
ILE C   O    doub N N 235 
ILE C   OXT  sing N N 236 
ILE CB  CG1  sing N N 237 
ILE CB  CG2  sing N N 238 
ILE CB  HB   sing N N 239 
ILE CG1 CD1  sing N N 240 
ILE CG1 HG12 sing N N 241 
ILE CG1 HG13 sing N N 242 
ILE CG2 HG21 sing N N 243 
ILE CG2 HG22 sing N N 244 
ILE CG2 HG23 sing N N 245 
ILE CD1 HD11 sing N N 246 
ILE CD1 HD12 sing N N 247 
ILE CD1 HD13 sing N N 248 
ILE OXT HXT  sing N N 249 
LEU N   CA   sing N N 250 
LEU N   H    sing N N 251 
LEU N   H2   sing N N 252 
LEU CA  C    sing N N 253 
LEU CA  CB   sing N N 254 
LEU CA  HA   sing N N 255 
LEU C   O    doub N N 256 
LEU C   OXT  sing N N 257 
LEU CB  CG   sing N N 258 
LEU CB  HB2  sing N N 259 
LEU CB  HB3  sing N N 260 
LEU CG  CD1  sing N N 261 
LEU CG  CD2  sing N N 262 
LEU CG  HG   sing N N 263 
LEU CD1 HD11 sing N N 264 
LEU CD1 HD12 sing N N 265 
LEU CD1 HD13 sing N N 266 
LEU CD2 HD21 sing N N 267 
LEU CD2 HD22 sing N N 268 
LEU CD2 HD23 sing N N 269 
LEU OXT HXT  sing N N 270 
LYS N   CA   sing N N 271 
LYS N   H    sing N N 272 
LYS N   H2   sing N N 273 
LYS CA  C    sing N N 274 
LYS CA  CB   sing N N 275 
LYS CA  HA   sing N N 276 
LYS C   O    doub N N 277 
LYS C   OXT  sing N N 278 
LYS CB  CG   sing N N 279 
LYS CB  HB2  sing N N 280 
LYS CB  HB3  sing N N 281 
LYS CG  CD   sing N N 282 
LYS CG  HG2  sing N N 283 
LYS CG  HG3  sing N N 284 
LYS CD  CE   sing N N 285 
LYS CD  HD2  sing N N 286 
LYS CD  HD3  sing N N 287 
LYS CE  NZ   sing N N 288 
LYS CE  HE2  sing N N 289 
LYS CE  HE3  sing N N 290 
LYS NZ  HZ1  sing N N 291 
LYS NZ  HZ2  sing N N 292 
LYS NZ  HZ3  sing N N 293 
LYS OXT HXT  sing N N 294 
MET N   CA   sing N N 295 
MET N   H    sing N N 296 
MET N   H2   sing N N 297 
MET CA  C    sing N N 298 
MET CA  CB   sing N N 299 
MET CA  HA   sing N N 300 
MET C   O    doub N N 301 
MET C   OXT  sing N N 302 
MET CB  CG   sing N N 303 
MET CB  HB2  sing N N 304 
MET CB  HB3  sing N N 305 
MET CG  SD   sing N N 306 
MET CG  HG2  sing N N 307 
MET CG  HG3  sing N N 308 
MET SD  CE   sing N N 309 
MET CE  HE1  sing N N 310 
MET CE  HE2  sing N N 311 
MET CE  HE3  sing N N 312 
MET OXT HXT  sing N N 313 
PHE N   CA   sing N N 314 
PHE N   H    sing N N 315 
PHE N   H2   sing N N 316 
PHE CA  C    sing N N 317 
PHE CA  CB   sing N N 318 
PHE CA  HA   sing N N 319 
PHE C   O    doub N N 320 
PHE C   OXT  sing N N 321 
PHE CB  CG   sing N N 322 
PHE CB  HB2  sing N N 323 
PHE CB  HB3  sing N N 324 
PHE CG  CD1  doub Y N 325 
PHE CG  CD2  sing Y N 326 
PHE CD1 CE1  sing Y N 327 
PHE CD1 HD1  sing N N 328 
PHE CD2 CE2  doub Y N 329 
PHE CD2 HD2  sing N N 330 
PHE CE1 CZ   doub Y N 331 
PHE CE1 HE1  sing N N 332 
PHE CE2 CZ   sing Y N 333 
PHE CE2 HE2  sing N N 334 
PHE CZ  HZ   sing N N 335 
PHE OXT HXT  sing N N 336 
PRO N   CA   sing N N 337 
PRO N   CD   sing N N 338 
PRO N   H    sing N N 339 
PRO CA  C    sing N N 340 
PRO CA  CB   sing N N 341 
PRO CA  HA   sing N N 342 
PRO C   O    doub N N 343 
PRO C   OXT  sing N N 344 
PRO CB  CG   sing N N 345 
PRO CB  HB2  sing N N 346 
PRO CB  HB3  sing N N 347 
PRO CG  CD   sing N N 348 
PRO CG  HG2  sing N N 349 
PRO CG  HG3  sing N N 350 
PRO CD  HD2  sing N N 351 
PRO CD  HD3  sing N N 352 
PRO OXT HXT  sing N N 353 
SER N   CA   sing N N 354 
SER N   H    sing N N 355 
SER N   H2   sing N N 356 
SER CA  C    sing N N 357 
SER CA  CB   sing N N 358 
SER CA  HA   sing N N 359 
SER C   O    doub N N 360 
SER C   OXT  sing N N 361 
SER CB  OG   sing N N 362 
SER CB  HB2  sing N N 363 
SER CB  HB3  sing N N 364 
SER OG  HG   sing N N 365 
SER OXT HXT  sing N N 366 
TAU C1  C2   sing N N 367 
TAU C1  N1   sing N N 368 
TAU C1  H1C1 sing N N 369 
TAU C1  H1C2 sing N N 370 
TAU C2  S    sing N N 371 
TAU C2  H2C1 sing N N 372 
TAU C2  H2C2 sing N N 373 
TAU N1  H1N1 sing N N 374 
TAU N1  H1N2 sing N N 375 
TAU S   O1   doub N N 376 
TAU S   O2   sing N N 377 
TAU S   O3   doub N N 378 
TAU O2  H2   sing N N 379 
THR N   CA   sing N N 380 
THR N   H    sing N N 381 
THR N   H2   sing N N 382 
THR CA  C    sing N N 383 
THR CA  CB   sing N N 384 
THR CA  HA   sing N N 385 
THR C   O    doub N N 386 
THR C   OXT  sing N N 387 
THR CB  OG1  sing N N 388 
THR CB  CG2  sing N N 389 
THR CB  HB   sing N N 390 
THR OG1 HG1  sing N N 391 
THR CG2 HG21 sing N N 392 
THR CG2 HG22 sing N N 393 
THR CG2 HG23 sing N N 394 
THR OXT HXT  sing N N 395 
TRP N   CA   sing N N 396 
TRP N   H    sing N N 397 
TRP N   H2   sing N N 398 
TRP CA  C    sing N N 399 
TRP CA  CB   sing N N 400 
TRP CA  HA   sing N N 401 
TRP C   O    doub N N 402 
TRP C   OXT  sing N N 403 
TRP CB  CG   sing N N 404 
TRP CB  HB2  sing N N 405 
TRP CB  HB3  sing N N 406 
TRP CG  CD1  doub Y N 407 
TRP CG  CD2  sing Y N 408 
TRP CD1 NE1  sing Y N 409 
TRP CD1 HD1  sing N N 410 
TRP CD2 CE2  doub Y N 411 
TRP CD2 CE3  sing Y N 412 
TRP NE1 CE2  sing Y N 413 
TRP NE1 HE1  sing N N 414 
TRP CE2 CZ2  sing Y N 415 
TRP CE3 CZ3  doub Y N 416 
TRP CE3 HE3  sing N N 417 
TRP CZ2 CH2  doub Y N 418 
TRP CZ2 HZ2  sing N N 419 
TRP CZ3 CH2  sing Y N 420 
TRP CZ3 HZ3  sing N N 421 
TRP CH2 HH2  sing N N 422 
TRP OXT HXT  sing N N 423 
TYR N   CA   sing N N 424 
TYR N   H    sing N N 425 
TYR N   H2   sing N N 426 
TYR CA  C    sing N N 427 
TYR CA  CB   sing N N 428 
TYR CA  HA   sing N N 429 
TYR C   O    doub N N 430 
TYR C   OXT  sing N N 431 
TYR CB  CG   sing N N 432 
TYR CB  HB2  sing N N 433 
TYR CB  HB3  sing N N 434 
TYR CG  CD1  doub Y N 435 
TYR CG  CD2  sing Y N 436 
TYR CD1 CE1  sing Y N 437 
TYR CD1 HD1  sing N N 438 
TYR CD2 CE2  doub Y N 439 
TYR CD2 HD2  sing N N 440 
TYR CE1 CZ   doub Y N 441 
TYR CE1 HE1  sing N N 442 
TYR CE2 CZ   sing Y N 443 
TYR CE2 HE2  sing N N 444 
TYR CZ  OH   sing N N 445 
TYR OH  HH   sing N N 446 
TYR OXT HXT  sing N N 447 
VAL N   CA   sing N N 448 
VAL N   H    sing N N 449 
VAL N   H2   sing N N 450 
VAL CA  C    sing N N 451 
VAL CA  CB   sing N N 452 
VAL CA  HA   sing N N 453 
VAL C   O    doub N N 454 
VAL C   OXT  sing N N 455 
VAL CB  CG1  sing N N 456 
VAL CB  CG2  sing N N 457 
VAL CB  HB   sing N N 458 
VAL CG1 HG11 sing N N 459 
VAL CG1 HG12 sing N N 460 
VAL CG1 HG13 sing N N 461 
VAL CG2 HG21 sing N N 462 
VAL CG2 HG22 sing N N 463 
VAL CG2 HG23 sing N N 464 
VAL OXT HXT  sing N N 465 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-10-23 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9K7B 
_em_admin.last_update        2025-02-26 
_em_admin.map_release_date   2025-02-26 
_em_admin.title              
'Cryo-EM structure of human taurine transporter TauT bound with taurine molecules in an inward-open state in the saposin-disc' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9K7B 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CL 
N  
NA 
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . SER A 1 57  ? 130.789 84.739  121.026 1.00 89.44 ? 45  SER A N   1 
ATOM   2    C  CA  . SER A 1 57  ? 131.159 85.899  120.223 1.00 89.44 ? 45  SER A CA  1 
ATOM   3    C  C   . SER A 1 57  ? 129.951 86.788  119.970 1.00 89.44 ? 45  SER A C   1 
ATOM   4    O  O   . SER A 1 57  ? 130.075 88.013  119.986 1.00 89.44 ? 45  SER A O   1 
ATOM   5    C  CB  . SER A 1 57  ? 131.777 85.453  118.896 1.00 89.44 ? 45  SER A CB  1 
ATOM   6    O  OG  . SER A 1 57  ? 130.859 84.690  118.132 1.00 89.44 ? 45  SER A OG  1 
ATOM   7    N  N   . SER A 1 58  ? 128.795 86.179  119.708 1.00 92.16 ? 46  SER A N   1 
ATOM   8    C  CA  . SER A 1 58  ? 127.559 86.934  119.482 1.00 92.16 ? 46  SER A CA  1 
ATOM   9    C  C   . SER A 1 58  ? 127.682 87.957  118.366 1.00 92.16 ? 46  SER A C   1 
ATOM   10   O  O   . SER A 1 58  ? 127.144 89.058  118.468 1.00 92.16 ? 46  SER A O   1 
ATOM   11   C  CB  . SER A 1 58  ? 127.060 87.590  120.775 1.00 92.16 ? 46  SER A CB  1 
ATOM   12   O  OG  . SER A 1 58  ? 126.784 86.616  121.766 1.00 92.16 ? 46  SER A OG  1 
ATOM   13   N  N   . LYS A 1 59  ? 128.386 87.600  117.298 1.00 93.59 ? 47  LYS A N   1 
ATOM   14   C  CA  . LYS A 1 59  ? 128.500 88.499  116.153 1.00 93.59 ? 47  LYS A CA  1 
ATOM   15   C  C   . LYS A 1 59  ? 127.134 88.729  115.529 1.00 93.59 ? 47  LYS A C   1 
ATOM   16   O  O   . LYS A 1 59  ? 126.813 89.844  115.124 1.00 93.59 ? 47  LYS A O   1 
ATOM   17   C  CB  . LYS A 1 59  ? 129.480 87.939  115.122 1.00 93.59 ? 47  LYS A CB  1 
ATOM   18   C  CG  . LYS A 1 59  ? 130.916 87.893  115.614 1.00 93.59 ? 47  LYS A CG  1 
ATOM   19   C  CD  . LYS A 1 59  ? 131.411 89.289  115.954 1.00 93.59 ? 47  LYS A CD  1 
ATOM   20   C  CE  . LYS A 1 59  ? 132.831 89.262  116.495 1.00 93.59 ? 47  LYS A CE  1 
ATOM   21   N  NZ  . LYS A 1 59  ? 132.913 88.559  117.804 1.00 93.59 ? 47  LYS A NZ  1 
ATOM   22   N  N   . ILE A 1 60  ? 126.326 87.679  115.452 1.00 94.88 ? 48  ILE A N   1 
ATOM   23   C  CA  . ILE A 1 60  ? 124.982 87.809  114.904 1.00 94.88 ? 48  ILE A CA  1 
ATOM   24   C  C   . ILE A 1 60  ? 124.125 88.759  115.744 1.00 94.88 ? 48  ILE A C   1 
ATOM   25   O  O   . ILE A 1 60  ? 123.411 89.599  115.202 1.00 94.88 ? 48  ILE A O   1 
ATOM   26   C  CB  . ILE A 1 60  ? 124.311 86.418  114.778 1.00 94.88 ? 48  ILE A CB  1 
ATOM   27   C  CG1 . ILE A 1 60  ? 125.025 85.545  113.744 1.00 94.88 ? 48  ILE A CG1 1 
ATOM   28   C  CG2 . ILE A 1 60  ? 122.837 86.561  114.427 1.00 94.88 ? 48  ILE A CG2 1 
ATOM   29   C  CD1 . ILE A 1 60  ? 124.587 84.098  113.763 1.00 94.88 ? 48  ILE A CD1 1 
ATOM   30   N  N   . ASP A 1 61  ? 124.224 88.662  117.065 1.00 94.65 ? 49  ASP A N   1 
ATOM   31   C  CA  . ASP A 1 61  ? 123.424 89.509  117.940 1.00 94.65 ? 49  ASP A CA  1 
ATOM   32   C  C   . ASP A 1 61  ? 123.878 90.956  117.825 1.00 94.65 ? 49  ASP A C   1 
ATOM   33   O  O   . ASP A 1 61  ? 123.075 91.878  117.951 1.00 94.65 ? 49  ASP A O   1 
ATOM   34   C  CB  . ASP A 1 61  ? 123.546 89.025  119.383 1.00 94.65 ? 49  ASP A CB  1 
ATOM   35   C  CG  . ASP A 1 61  ? 122.325 89.356  120.216 1.00 94.65 ? 49  ASP A CG  1 
ATOM   36   O  OD1 . ASP A 1 61  ? 121.312 89.806  119.641 1.00 94.65 ? 49  ASP A OD1 1 
ATOM   37   O  OD2 . ASP A 1 61  ? 122.375 89.156  121.448 1.00 94.65 ? 49  ASP A OD2 1 
ATOM   38   N  N   . PHE A 1 62  ? 125.160 91.153  117.552 1.00 95.58 ? 50  PHE A N   1 
ATOM   39   C  CA  . PHE A 1 62  ? 125.697 92.499  117.422 1.00 95.58 ? 50  PHE A CA  1 
ATOM   40   C  C   . PHE A 1 62  ? 125.163 93.186  116.183 1.00 95.58 ? 50  PHE A C   1 
ATOM   41   O  O   . PHE A 1 62  ? 124.721 94.332  116.251 1.00 95.58 ? 50  PHE A O   1 
ATOM   42   C  CB  . PHE A 1 62  ? 127.221 92.440  117.357 1.00 95.58 ? 50  PHE A CB  1 
ATOM   43   C  CG  . PHE A 1 62  ? 127.887 93.784  117.382 1.00 95.58 ? 50  PHE A CG  1 
ATOM   44   C  CD1 . PHE A 1 62  ? 127.800 94.594  118.501 1.00 95.58 ? 50  PHE A CD1 1 
ATOM   45   C  CD2 . PHE A 1 62  ? 128.620 94.228  116.294 1.00 95.58 ? 50  PHE A CD2 1 
ATOM   46   C  CE1 . PHE A 1 62  ? 128.420 95.828  118.530 1.00 95.58 ? 50  PHE A CE1 1 
ATOM   47   C  CE2 . PHE A 1 62  ? 129.243 95.461  116.317 1.00 95.58 ? 50  PHE A CE2 1 
ATOM   48   C  CZ  . PHE A 1 62  ? 129.144 96.262  117.438 1.00 95.58 ? 50  PHE A CZ  1 
ATOM   49   N  N   . VAL A 1 63  ? 125.173 92.491  115.051 1.00 96.84 ? 51  VAL A N   1 
ATOM   50   C  CA  . VAL A 1 63  ? 124.771 93.146  113.809 1.00 96.84 ? 51  VAL A CA  1 
ATOM   51   C  C   . VAL A 1 63  ? 123.327 93.636  113.820 1.00 96.84 ? 51  VAL A C   1 
ATOM   52   O  O   . VAL A 1 63  ? 123.059 94.715  113.329 1.00 96.84 ? 51  VAL A O   1 
ATOM   53   C  CB  . VAL A 1 63  ? 125.073 92.310  112.535 1.00 96.84 ? 51  VAL A CB  1 
ATOM   54   C  CG1 . VAL A 1 63  ? 126.562 92.019  112.430 1.00 96.84 ? 51  VAL A CG1 1 
ATOM   55   C  CG2 . VAL A 1 63  ? 124.266 91.025  112.487 1.00 96.84 ? 51  VAL A CG2 1 
ATOM   56   N  N   . LEU A 1 64  ? 122.396 92.869  114.377 1.00 96.29 ? 52  LEU A N   1 
ATOM   57   C  CA  . LEU A 1 64  ? 121.005 93.295  114.324 1.00 96.29 ? 52  LEU A CA  1 
ATOM   58   C  C   . LEU A 1 64  ? 120.802 94.601  115.079 1.00 96.29 ? 52  LEU A C   1 
ATOM   59   O  O   . LEU A 1 64  ? 120.088 95.483  114.606 1.00 96.29 ? 52  LEU A O   1 
ATOM   60   C  CB  . LEU A 1 64  ? 120.060 92.190  114.810 1.00 96.29 ? 52  LEU A CB  1 
ATOM   61   C  CG  . LEU A 1 64  ? 118.550 92.423  114.912 1.00 96.29 ? 52  LEU A CG  1 
ATOM   62   C  CD1 . LEU A 1 64  ? 117.942 92.708  113.547 1.00 96.29 ? 52  LEU A CD1 1 
ATOM   63   C  CD2 . LEU A 1 64  ? 117.880 91.207  115.531 1.00 96.29 ? 52  LEU A CD2 1 
ATOM   64   N  N   . SER A 1 65  ? 121.433 94.736  116.241 1.00 95.89 ? 53  SER A N   1 
ATOM   65   C  CA  . SER A 1 65  ? 121.342 95.974  117.007 1.00 95.89 ? 53  SER A CA  1 
ATOM   66   C  C   . SER A 1 65  ? 121.971 97.130  116.249 1.00 95.89 ? 53  SER A C   1 
ATOM   67   O  O   . SER A 1 65  ? 121.434 98.237  116.235 1.00 95.89 ? 53  SER A O   1 
ATOM   68   C  CB  . SER A 1 65  ? 122.027 95.806  118.361 1.00 95.89 ? 53  SER A CB  1 
ATOM   69   O  OG  . SER A 1 65  ? 121.435 94.753  119.100 1.00 95.89 ? 53  SER A OG  1 
ATOM   70   N  N   . VAL A 1 66  ? 123.097 96.879  115.587 1.00 96.75 ? 54  VAL A N   1 
ATOM   71   C  CA  . VAL A 1 66  ? 123.804 97.929  114.845 1.00 96.75 ? 54  VAL A CA  1 
ATOM   72   C  C   . VAL A 1 66  ? 123.181 98.228  113.480 1.00 96.75 ? 54  VAL A C   1 
ATOM   73   O  O   . VAL A 1 66  ? 123.146 99.384  113.048 1.00 96.75 ? 54  VAL A O   1 
ATOM   74   C  CB  . VAL A 1 66  ? 125.291 97.547  114.681 1.00 96.75 ? 54  VAL A CB  1 
ATOM   75   C  CG1 . VAL A 1 66  ? 126.036 98.539  113.801 1.00 96.75 ? 54  VAL A CG1 1 
ATOM   76   C  CG2 . VAL A 1 66  ? 125.952 97.459  116.045 1.00 96.75 ? 54  VAL A CG2 1 
ATOM   77   N  N   . ALA A 1 67  ? 122.692 97.210  112.779 1.00 96.06 ? 55  ALA A N   1 
ATOM   78   C  CA  . ALA A 1 67  ? 122.170 97.421  111.421 1.00 96.06 ? 55  ALA A CA  1 
ATOM   79   C  C   . ALA A 1 67  ? 120.790 98.047  111.363 1.00 96.06 ? 55  ALA A C   1 
ATOM   80   O  O   . ALA A 1 67  ? 120.256 98.482  112.384 1.00 96.06 ? 55  ALA A O   1 
ATOM   81   C  CB  . ALA A 1 67  ? 122.188 96.122  110.630 1.00 96.06 ? 55  ALA A CB  1 
ATOM   82   N  N   . GLY A 1 68  ? 120.212 98.095  110.165 1.00 93.88 ? 56  GLY A N   1 
ATOM   83   C  CA  . GLY A 1 68  ? 118.899 98.694  109.994 1.00 93.88 ? 56  GLY A CA  1 
ATOM   84   C  C   . GLY A 1 68  ? 117.918 98.238  111.049 1.00 93.88 ? 56  GLY A C   1 
ATOM   85   O  O   . GLY A 1 68  ? 117.748 97.032  111.250 1.00 93.88 ? 56  GLY A O   1 
ATOM   86   N  N   . GLY A 1 69  ? 117.267 99.184  111.725 1.00 92.63 ? 57  GLY A N   1 
ATOM   87   C  CA  . GLY A 1 69  ? 116.353 98.834  112.793 1.00 92.63 ? 57  GLY A CA  1 
ATOM   88   C  C   . GLY A 1 69  ? 115.289 97.898  112.287 1.00 92.63 ? 57  GLY A C   1 
ATOM   89   O  O   . GLY A 1 69  ? 114.805 98.057  111.169 1.00 92.63 ? 57  GLY A O   1 
ATOM   90   N  N   . PHE A 1 70  ? 114.932 96.905  113.087 1.00 91.79 ? 58  PHE A N   1 
ATOM   91   C  CA  . PHE A 1 70  ? 113.848 96.014  112.696 1.00 91.79 ? 58  PHE A CA  1 
ATOM   92   C  C   . PHE A 1 70  ? 112.556 96.337  113.433 1.00 91.79 ? 58  PHE A C   1 
ATOM   93   O  O   . PHE A 1 70  ? 111.743 95.449  113.672 1.00 91.79 ? 58  PHE A O   1 
ATOM   94   C  CB  . PHE A 1 70  ? 114.241 94.528  112.766 1.00 91.79 ? 58  PHE A CB  1 
ATOM   95   C  CG  . PHE A 1 70  ? 115.038 94.151  113.980 1.00 91.79 ? 58  PHE A CG  1 
ATOM   96   C  CD1 . PHE A 1 70  ? 116.385 94.459  114.073 1.00 91.79 ? 58  PHE A CD1 1 
ATOM   97   C  CD2 . PHE A 1 70  ? 114.450 93.447  115.010 1.00 91.79 ? 58  PHE A CD2 1 
ATOM   98   C  CE1 . PHE A 1 70  ? 117.116 94.108  115.186 1.00 91.79 ? 58  PHE A CE1 1 
ATOM   99   C  CE2 . PHE A 1 70  ? 115.182 93.076  116.118 1.00 91.79 ? 58  PHE A CE2 1 
ATOM   100  C  CZ  . PHE A 1 70  ? 116.514 93.413  116.211 1.00 91.79 ? 58  PHE A CZ  1 
ATOM   101  N  N   . VAL A 1 71  ? 112.381 97.594  113.838 1.00 93.56 ? 59  VAL A N   1 
ATOM   102  C  CA  . VAL A 1 71  ? 111.115 98.005  114.426 1.00 93.56 ? 59  VAL A CA  1 
ATOM   103  C  C   . VAL A 1 71  ? 110.900 99.411  113.932 1.00 93.56 ? 59  VAL A C   1 
ATOM   104  O  O   . VAL A 1 71  ? 111.854 100.160 113.758 1.00 93.56 ? 59  VAL A O   1 
ATOM   105  C  CB  . VAL A 1 71  ? 111.066 98.071  115.943 1.00 93.56 ? 59  VAL A CB  1 
ATOM   106  C  CG1 . VAL A 1 71  ? 109.610 98.115  116.369 1.00 93.56 ? 59  VAL A CG1 1 
ATOM   107  C  CG2 . VAL A 1 71  ? 111.775 96.904  116.577 1.00 93.56 ? 59  VAL A CG2 1 
ATOM   108  N  N   . GLY A 1 72  ? 109.655 99.782  113.711 1.00 92.94 ? 60  GLY A N   1 
ATOM   109  C  CA  . GLY A 1 72  ? 109.356 101.089 113.193 1.00 92.94 ? 60  GLY A CA  1 
ATOM   110  C  C   . GLY A 1 72  ? 107.911 101.284 113.505 1.00 92.94 ? 60  GLY A C   1 
ATOM   111  O  O   . GLY A 1 72  ? 107.279 100.414 114.088 1.00 92.94 ? 60  GLY A O   1 
ATOM   112  N  N   . LEU A 1 73  ? 107.384 102.439 113.166 1.00 91.30 ? 61  LEU A N   1 
ATOM   113  C  CA  . LEU A 1 73  ? 105.972 102.637 113.350 1.00 91.30 ? 61  LEU A CA  1 
ATOM   114  C  C   . LEU A 1 73  ? 105.184 101.728 112.420 1.00 91.30 ? 61  LEU A C   1 
ATOM   115  O  O   . LEU A 1 73  ? 104.016 101.513 112.653 1.00 91.30 ? 61  LEU A O   1 
ATOM   116  C  CB  . LEU A 1 73  ? 105.598 104.095 113.115 1.00 91.30 ? 61  LEU A CB  1 
ATOM   117  C  CG  . LEU A 1 73  ? 106.210 105.098 114.084 1.00 91.30 ? 61  LEU A CG  1 
ATOM   118  C  CD1 . LEU A 1 73  ? 105.608 106.465 113.821 1.00 91.30 ? 61  LEU A CD1 1 
ATOM   119  C  CD2 . LEU A 1 73  ? 105.947 104.657 115.513 1.00 91.30 ? 61  LEU A CD2 1 
ATOM   120  N  N   . GLY A 1 74  ? 105.794 101.181 111.373 1.00 89.90 ? 62  GLY A N   1 
ATOM   121  C  CA  . GLY A 1 74  ? 105.029 100.279 110.541 1.00 89.90 ? 62  GLY A CA  1 
ATOM   122  C  C   . GLY A 1 74  ? 104.695 99.013  111.285 1.00 89.90 ? 62  GLY A C   1 
ATOM   123  O  O   . GLY A 1 74  ? 103.589 98.511  111.164 1.00 89.90 ? 62  GLY A O   1 
ATOM   124  N  N   . ASN A 1 75  ? 105.611 98.522  112.100 1.00 93.74 ? 63  ASN A N   1 
ATOM   125  C  CA  . ASN A 1 75  ? 105.342 97.351  112.917 1.00 93.74 ? 63  ASN A CA  1 
ATOM   126  C  C   . ASN A 1 75  ? 104.310 97.680  113.966 1.00 93.74 ? 63  ASN A C   1 
ATOM   127  O  O   . ASN A 1 75  ? 103.267 97.050  114.024 1.00 93.74 ? 63  ASN A O   1 
ATOM   128  C  CB  . ASN A 1 75  ? 106.620 96.920  113.623 1.00 93.74 ? 63  ASN A CB  1 
ATOM   129  C  CG  . ASN A 1 75  ? 107.565 96.163  112.722 1.00 93.74 ? 63  ASN A CG  1 
ATOM   130  O  OD1 . ASN A 1 75  ? 108.650 95.778  113.141 1.00 93.74 ? 63  ASN A OD1 1 
ATOM   131  N  ND2 . ASN A 1 75  ? 107.156 95.938  111.485 1.00 93.74 ? 63  ASN A ND2 1 
ATOM   132  N  N   . VAL A 1 76  ? 104.620 98.634  114.832 1.00 90.81 ? 64  VAL A N   1 
ATOM   133  C  CA  . VAL A 1 76  ? 103.713 99.035  115.910 1.00 90.81 ? 64  VAL A CA  1 
ATOM   134  C  C   . VAL A 1 76  ? 102.394 99.704  115.503 1.00 90.81 ? 64  VAL A C   1 
ATOM   135  O  O   . VAL A 1 76  ? 101.363 99.444  116.114 1.00 90.81 ? 64  VAL A O   1 
ATOM   136  C  CB  . VAL A 1 76  ? 104.471 99.898  116.941 1.00 90.81 ? 64  VAL A CB  1 
ATOM   137  C  CG1 . VAL A 1 76  ? 103.679 100.031 118.230 1.00 90.81 ? 64  VAL A CG1 1 
ATOM   138  C  CG2 . VAL A 1 76  ? 105.825 99.277  117.232 1.00 90.81 ? 64  VAL A CG2 1 
ATOM   139  N  N   . TRP A 1 77  ? 102.418 100.585 114.509 1.00 85.00 ? 65  TRP A N   1 
ATOM   140  C  CA  . TRP A 1 77  ? 101.210 101.309 114.113 1.00 85.00 ? 65  TRP A CA  1 
ATOM   141  C  C   . TRP A 1 77  ? 100.593 101.011 112.730 1.00 85.00 ? 65  TRP A C   1 
ATOM   142  O  O   . TRP A 1 77  ? 99.407  101.189 112.525 1.00 85.00 ? 65  TRP A O   1 
ATOM   143  C  CB  . TRP A 1 77  ? 101.463 102.826 114.283 1.00 85.00 ? 65  TRP A CB  1 
ATOM   144  C  CG  . TRP A 1 77  ? 100.466 103.701 113.598 1.00 85.00 ? 65  TRP A CG  1 
ATOM   145  C  CD1 . TRP A 1 77  ? 99.302  104.181 114.117 1.00 85.00 ? 65  TRP A CD1 1 
ATOM   146  C  CD2 . TRP A 1 77  ? 100.535 104.183 112.253 1.00 85.00 ? 65  TRP A CD2 1 
ATOM   147  N  NE1 . TRP A 1 77  ? 98.640  104.928 113.177 1.00 85.00 ? 65  TRP A NE1 1 
ATOM   148  C  CE2 . TRP A 1 77  ? 99.378  104.941 112.023 1.00 85.00 ? 65  TRP A CE2 1 
ATOM   149  C  CE3 . TRP A 1 77  ? 101.462 104.038 111.220 1.00 85.00 ? 65  TRP A CE3 1 
ATOM   150  C  CZ2 . TRP A 1 77  ? 99.127  105.556 110.808 1.00 85.00 ? 65  TRP A CZ2 1 
ATOM   151  C  CZ3 . TRP A 1 77  ? 101.208 104.646 110.017 1.00 85.00 ? 65  TRP A CZ3 1 
ATOM   152  C  CH2 . TRP A 1 77  ? 100.052 105.394 109.818 1.00 85.00 ? 65  TRP A CH2 1 
ATOM   153  N  N   . ARG A 1 78  ? 101.359 100.601 111.744 1.00 88.97 ? 66  ARG A N   1 
ATOM   154  C  CA  . ARG A 1 78  ? 100.715 100.384 110.458 1.00 88.97 ? 66  ARG A CA  1 
ATOM   155  C  C   . ARG A 1 78  ? 100.113 98.994  110.424 1.00 88.97 ? 66  ARG A C   1 
ATOM   156  O  O   . ARG A 1 78  ? 98.980  98.821  110.000 1.00 88.97 ? 66  ARG A O   1 
ATOM   157  C  CB  . ARG A 1 78  ? 101.679 100.624 109.296 1.00 88.97 ? 66  ARG A CB  1 
ATOM   158  C  CG  . ARG A 1 78  ? 101.078 100.539 107.909 1.00 88.97 ? 66  ARG A CG  1 
ATOM   159  C  CD  . ARG A 1 78  ? 102.085 100.886 106.840 1.00 88.97 ? 66  ARG A CD  1 
ATOM   160  N  NE  . ARG A 1 78  ? 101.507 100.780 105.510 1.00 88.97 ? 66  ARG A NE  1 
ATOM   161  C  CZ  . ARG A 1 78  ? 100.789 101.731 104.932 1.00 88.97 ? 66  ARG A CZ  1 
ATOM   162  N  NH1 . ARG A 1 78  ? 100.543 102.860 105.575 1.00 88.97 ? 66  ARG A NH1 1 
ATOM   163  N  NH2 . ARG A 1 78  ? 100.302 101.544 103.717 1.00 88.97 ? 66  ARG A NH2 1 
ATOM   164  N  N   . PHE A 1 79  ? 100.858 97.999  110.890 1.00 93.91 ? 67  PHE A N   1 
ATOM   165  C  CA  . PHE A 1 79  ? 100.379 96.626  110.816 1.00 93.91 ? 67  PHE A CA  1 
ATOM   166  C  C   . PHE A 1 79  ? 99.114  96.354  111.605 1.00 93.91 ? 67  PHE A C   1 
ATOM   167  O  O   . PHE A 1 79  ? 98.210  95.706  111.091 1.00 93.91 ? 67  PHE A O   1 
ATOM   168  C  CB  . PHE A 1 79  ? 101.490 95.643  111.214 1.00 93.91 ? 67  PHE A CB  1 
ATOM   169  C  CG  . PHE A 1 79  ? 101.042 94.212  111.299 1.00 93.91 ? 67  PHE A CG  1 
ATOM   170  C  CD1 . PHE A 1 79  ? 101.028 93.412  110.173 1.00 93.91 ? 67  PHE A CD1 1 
ATOM   171  C  CD2 . PHE A 1 79  ? 100.648 93.662  112.508 1.00 93.91 ? 67  PHE A CD2 1 
ATOM   172  C  CE1 . PHE A 1 79  ? 100.619 92.097  110.248 1.00 93.91 ? 67  PHE A CE1 1 
ATOM   173  C  CE2 . PHE A 1 79  ? 100.231 92.352  112.585 1.00 93.91 ? 67  PHE A CE2 1 
ATOM   174  C  CZ  . PHE A 1 79  ? 100.222 91.566  111.455 1.00 93.91 ? 67  PHE A CZ  1 
ATOM   175  N  N   . PRO A 1 80  ? 99.027  96.824  112.876 1.00 92.04 ? 68  PRO A N   1 
ATOM   176  C  CA  . PRO A 1 80  ? 97.759  96.508  113.538 1.00 92.04 ? 68  PRO A CA  1 
ATOM   177  C  C   . PRO A 1 80  ? 96.534  97.119  112.871 1.00 92.04 ? 68  PRO A C   1 
ATOM   178  O  O   . PRO A 1 80  ? 95.521  96.441  112.780 1.00 92.04 ? 68  PRO A O   1 
ATOM   179  C  CB  . PRO A 1 80  ? 97.952  97.104  114.922 1.00 92.04 ? 68  PRO A CB  1 
ATOM   180  C  CG  . PRO A 1 80  ? 99.401  96.977  115.165 1.00 92.04 ? 68  PRO A CG  1 
ATOM   181  C  CD  . PRO A 1 80  ? 99.972  97.407  113.858 1.00 92.04 ? 68  PRO A CD  1 
ATOM   182  N  N   . TYR A 1 81  ? 96.607  98.374  112.442 1.00 87.77 ? 69  TYR A N   1 
ATOM   183  C  CA  . TYR A 1 81  ? 95.447  99.044  111.863 1.00 87.77 ? 69  TYR A CA  1 
ATOM   184  C  C   . TYR A 1 81  ? 94.989  98.408  110.573 1.00 87.77 ? 69  TYR A C   1 
ATOM   185  O  O   . TYR A 1 81  ? 93.795  98.286  110.339 1.00 87.77 ? 69  TYR A O   1 
ATOM   186  C  CB  . TYR A 1 81  ? 95.669  100.566 111.775 1.00 87.77 ? 69  TYR A CB  1 
ATOM   187  C  CG  . TYR A 1 81  ? 95.818  101.193 110.405 1.00 87.77 ? 69  TYR A CG  1 
ATOM   188  C  CD1 . TYR A 1 81  ? 94.718  101.391 109.579 1.00 87.77 ? 69  TYR A CD1 1 
ATOM   189  C  CD2 . TYR A 1 81  ? 97.049  101.648 109.967 1.00 87.77 ? 69  TYR A CD2 1 
ATOM   190  C  CE1 . TYR A 1 81  ? 94.850  101.978 108.342 1.00 87.77 ? 69  TYR A CE1 1 
ATOM   191  C  CE2 . TYR A 1 81  ? 97.188  102.236 108.730 1.00 87.77 ? 69  TYR A CE2 1 
ATOM   192  C  CZ  . TYR A 1 81  ? 96.083  102.400 107.925 1.00 87.77 ? 69  TYR A CZ  1 
ATOM   193  O  OH  . TYR A 1 81  ? 96.207  102.990 106.694 1.00 87.77 ? 69  TYR A OH  1 
ATOM   194  N  N   . LEU A 1 82  ? 95.931  98.000  109.735 1.00 91.52 ? 70  LEU A N   1 
ATOM   195  C  CA  . LEU A 1 82  ? 95.599  97.378  108.466 1.00 91.52 ? 70  LEU A CA  1 
ATOM   196  C  C   . LEU A 1 82  ? 95.010  96.013  108.704 1.00 91.52 ? 70  LEU A C   1 
ATOM   197  O  O   . LEU A 1 82  ? 94.070  95.629  108.028 1.00 91.52 ? 70  LEU A O   1 
ATOM   198  C  CB  . LEU A 1 82  ? 96.843  97.283  107.596 1.00 91.52 ? 70  LEU A CB  1 
ATOM   199  C  CG  . LEU A 1 82  ? 97.174  98.597  106.917 1.00 91.52 ? 70  LEU A CG  1 
ATOM   200  C  CD1 . LEU A 1 82  ? 98.398  98.445  106.036 1.00 91.52 ? 70  LEU A CD1 1 
ATOM   201  C  CD2 . LEU A 1 82  ? 95.955  98.945  106.094 1.00 91.52 ? 70  LEU A CD2 1 
ATOM   202  N  N   . CYS A 1 83  ? 95.556  95.275  109.659 1.00 93.47 ? 71  CYS A N   1 
ATOM   203  C  CA  . CYS A 1 83  ? 95.012  93.979  110.008 1.00 93.47 ? 71  CYS A CA  1 
ATOM   204  C  C   . CYS A 1 83  ? 93.583  94.175  110.438 1.00 93.47 ? 71  CYS A C   1 
ATOM   205  O  O   . CYS A 1 83  ? 92.691  93.641  109.832 1.00 93.47 ? 71  CYS A O   1 
ATOM   206  C  CB  . CYS A 1 83  ? 95.824  93.373  111.145 1.00 93.47 ? 71  CYS A CB  1 
ATOM   207  S  SG  . CYS A 1 83  ? 95.731  91.585  111.323 1.00 93.47 ? 71  CYS A SG  1 
ATOM   208  N  N   . TYR A 1 84  ? 93.347  95.008  111.432 1.00 89.00 ? 72  TYR A N   1 
ATOM   209  C  CA  . TYR A 1 84  ? 92.015  95.220  111.976 1.00 89.00 ? 72  TYR A CA  1 
ATOM   210  C  C   . TYR A 1 84  ? 91.007  95.653  110.914 1.00 89.00 ? 72  TYR A C   1 
ATOM   211  O  O   . TYR A 1 84  ? 89.896  95.133  110.883 1.00 89.00 ? 72  TYR A O   1 
ATOM   212  C  CB  . TYR A 1 84  ? 92.145  96.281  113.057 1.00 89.00 ? 72  TYR A CB  1 
ATOM   213  C  CG  . TYR A 1 84  ? 90.939  96.546  113.897 1.00 89.00 ? 72  TYR A CG  1 
ATOM   214  C  CD1 . TYR A 1 84  ? 90.414  95.571  114.725 1.00 89.00 ? 72  TYR A CD1 1 
ATOM   215  C  CD2 . TYR A 1 84  ? 90.360  97.797  113.906 1.00 89.00 ? 72  TYR A CD2 1 
ATOM   216  C  CE1 . TYR A 1 84  ? 89.316  95.834  115.515 1.00 89.00 ? 72  TYR A CE1 1 
ATOM   217  C  CE2 . TYR A 1 84  ? 89.267  98.066  114.688 1.00 89.00 ? 72  TYR A CE2 1 
ATOM   218  C  CZ  . TYR A 1 84  ? 88.751  97.087  115.490 1.00 89.00 ? 72  TYR A CZ  1 
ATOM   219  O  OH  . TYR A 1 84  ? 87.663  97.384  116.265 1.00 89.00 ? 72  TYR A OH  1 
ATOM   220  N  N   . LYS A 1 85  ? 91.372  96.602  110.061 1.00 87.31 ? 73  LYS A N   1 
ATOM   221  C  CA  . LYS A 1 85  ? 90.479  97.069  109.007 1.00 87.31 ? 73  LYS A CA  1 
ATOM   222  C  C   . LYS A 1 85  ? 90.112  95.924  108.088 1.00 87.31 ? 73  LYS A C   1 
ATOM   223  O  O   . LYS A 1 85  ? 89.008  95.883  107.551 1.00 87.31 ? 73  LYS A O   1 
ATOM   224  C  CB  . LYS A 1 85  ? 91.166  98.177  108.210 1.00 87.31 ? 73  LYS A CB  1 
ATOM   225  C  CG  . LYS A 1 85  ? 90.317  98.817  107.129 1.00 87.31 ? 73  LYS A CG  1 
ATOM   226  C  CD  . LYS A 1 85  ? 91.134  99.050  105.872 1.00 87.31 ? 73  LYS A CD  1 
ATOM   227  C  CE  . LYS A 1 85  ? 92.264  100.031 106.120 1.00 87.31 ? 73  LYS A CE  1 
ATOM   228  N  NZ  . LYS A 1 85  ? 91.761  101.422 106.280 1.00 87.31 ? 73  LYS A NZ  1 
ATOM   229  N  N   . ASN A 1 86  ? 91.025  94.976  107.913 1.00 91.69 ? 74  ASN A N   1 
ATOM   230  C  CA  . ASN A 1 86  ? 90.801  93.857  107.001 1.00 91.69 ? 74  ASN A CA  1 
ATOM   231  C  C   . ASN A 1 86  ? 90.420  92.539  107.667 1.00 91.69 ? 74  ASN A C   1 
ATOM   232  O  O   . ASN A 1 86  ? 90.463  91.497  107.022 1.00 91.69 ? 74  ASN A O   1 
ATOM   233  C  CB  . ASN A 1 86  ? 92.032  93.669  106.127 1.00 91.69 ? 74  ASN A CB  1 
ATOM   234  C  CG  . ASN A 1 86  ? 92.290  94.853  105.224 1.00 91.69 ? 74  ASN A CG  1 
ATOM   235  O  OD1 . ASN A 1 86  ? 91.440  95.233  104.423 1.00 91.69 ? 74  ASN A OD1 1 
ATOM   236  N  ND2 . ASN A 1 86  ? 93.470  95.439  105.344 1.00 91.69 ? 74  ASN A ND2 1 
ATOM   237  N  N   . GLY A 1 87  ? 90.088  92.560  108.952 1.00 91.02 ? 75  GLY A N   1 
ATOM   238  C  CA  . GLY A 1 87  ? 89.749  91.347  109.688 1.00 91.02 ? 75  GLY A CA  1 
ATOM   239  C  C   . GLY A 1 87  ? 91.042  90.881  110.302 1.00 91.02 ? 75  GLY A C   1 
ATOM   240  O  O   . GLY A 1 87  ? 92.114  91.155  109.781 1.00 91.02 ? 75  GLY A O   1 
ATOM   241  N  N   . GLY A 1 88  ? 91.016  90.244  111.453 1.00 91.72 ? 76  GLY A N   1 
ATOM   242  C  CA  . GLY A 1 88  ? 92.311  89.868  111.971 1.00 91.72 ? 76  GLY A CA  1 
ATOM   243  C  C   . GLY A 1 88  ? 93.008  88.739  111.256 1.00 91.72 ? 76  GLY A C   1 
ATOM   244  O  O   . GLY A 1 88  ? 94.147  88.879  110.833 1.00 91.72 ? 76  GLY A O   1 
ATOM   245  N  N   . GLY A 1 89  ? 92.320  87.620  111.092 1.00 94.05 ? 77  GLY A N   1 
ATOM   246  C  CA  . GLY A 1 89  ? 92.923  86.454  110.473 1.00 94.05 ? 77  GLY A CA  1 
ATOM   247  C  C   . GLY A 1 89  ? 93.202  86.457  109.007 1.00 94.05 ? 77  GLY A C   1 
ATOM   248  O  O   . GLY A 1 89  ? 94.248  85.996  108.571 1.00 94.05 ? 77  GLY A O   1 
ATOM   249  N  N   . ALA A 1 90  ? 92.254  86.963  108.237 1.00 96.45 ? 78  ALA A N   1 
ATOM   250  C  CA  . ALA A 1 90  ? 92.391  86.933  106.802 1.00 96.45 ? 78  ALA A CA  1 
ATOM   251  C  C   . ALA A 1 90  ? 93.613  87.684  106.391 1.00 96.45 ? 78  ALA A C   1 
ATOM   252  O  O   . ALA A 1 90  ? 94.331  87.225  105.532 1.00 96.45 ? 78  ALA A O   1 
ATOM   253  C  CB  . ALA A 1 90  ? 91.170  87.541  106.153 1.00 96.45 ? 78  ALA A CB  1 
ATOM   254  N  N   . PHE A 1 91  ? 93.865  88.829  107.011 1.00 96.50 ? 79  PHE A N   1 
ATOM   255  C  CA  . PHE A 1 91  ? 94.988  89.665  106.596 1.00 96.50 ? 79  PHE A CA  1 
ATOM   256  C  C   . PHE A 1 91  ? 96.290  88.902  106.634 1.00 96.50 ? 79  PHE A C   1 
ATOM   257  O  O   . PHE A 1 91  ? 97.156  89.111  105.793 1.00 96.50 ? 79  PHE A O   1 
ATOM   258  C  CB  . PHE A 1 91  ? 95.062  90.861  107.537 1.00 96.50 ? 79  PHE A CB  1 
ATOM   259  C  CG  . PHE A 1 91  ? 96.117  91.868  107.186 1.00 96.50 ? 79  PHE A CG  1 
ATOM   260  C  CD1 . PHE A 1 91  ? 95.856  92.862  106.265 1.00 96.50 ? 79  PHE A CD1 1 
ATOM   261  C  CD2 . PHE A 1 91  ? 97.355  91.847  107.809 1.00 96.50 ? 79  PHE A CD2 1 
ATOM   262  C  CE1 . PHE A 1 91  ? 96.814  93.801  105.955 1.00 96.50 ? 79  PHE A CE1 1 
ATOM   263  C  CE2 . PHE A 1 91  ? 98.319  92.782  107.499 1.00 96.50 ? 79  PHE A CE2 1 
ATOM   264  C  CZ  . PHE A 1 91  ? 98.048  93.761  106.572 1.00 96.50 ? 79  PHE A CZ  1 
ATOM   265  N  N   . LEU A 1 92  ? 96.417  87.978  107.573 1.00 96.48 ? 80  LEU A N   1 
ATOM   266  C  CA  . LEU A 1 92  ? 97.661  87.242  107.726 1.00 96.48 ? 80  LEU A CA  1 
ATOM   267  C  C   . LEU A 1 92  ? 98.025  86.329  106.545 1.00 96.48 ? 80  LEU A C   1 
ATOM   268  O  O   . LEU A 1 92  ? 99.197  86.184  106.234 1.00 96.48 ? 80  LEU A O   1 
ATOM   269  C  CB  . LEU A 1 92  ? 97.662  86.481  109.048 1.00 96.48 ? 80  LEU A CB  1 
ATOM   270  C  CG  . LEU A 1 92  ? 97.619  87.371  110.290 1.00 96.48 ? 80  LEU A CG  1 
ATOM   271  C  CD1 . LEU A 1 92  ? 97.578  86.530  111.554 1.00 96.48 ? 80  LEU A CD1 1 
ATOM   272  C  CD2 . LEU A 1 92  ? 98.814  88.311  110.307 1.00 96.48 ? 80  LEU A CD2 1 
ATOM   273  N  N   . ILE A 1 93  ? 97.052  85.713  105.887 1.00 96.18 ? 81  ILE A N   1 
ATOM   274  C  CA  . ILE A 1 93  ? 97.411  84.843  104.781 1.00 96.18 ? 81  ILE A CA  1 
ATOM   275  C  C   . ILE A 1 93  ? 98.088  85.584  103.618 1.00 96.18 ? 81  ILE A C   1 
ATOM   276  O  O   . ILE A 1 93  ? 99.166  85.183  103.193 1.00 96.18 ? 81  ILE A O   1 
ATOM   277  C  CB  . ILE A 1 93  ? 96.199  84.005  104.303 1.00 96.18 ? 81  ILE A CB  1 
ATOM   278  C  CG1 . ILE A 1 93  ? 95.446  83.438  105.507 1.00 96.18 ? 81  ILE A CG1 1 
ATOM   279  C  CG2 . ILE A 1 93  ? 96.637  82.906  103.350 1.00 96.18 ? 81  ILE A CG2 1 
ATOM   280  C  CD1 . ILE A 1 93  ? 94.166  82.719  105.145 1.00 96.18 ? 81  ILE A CD1 1 
ATOM   281  N  N   . PRO A 1 94  ? 97.491  86.696  103.101 1.00 95.06 ? 82  PRO A N   1 
ATOM   282  C  CA  . PRO A 1 94  ? 98.261  87.398  102.069 1.00 95.06 ? 82  PRO A CA  1 
ATOM   283  C  C   . PRO A 1 94  ? 99.560  87.960  102.615 1.00 95.06 ? 82  PRO A C   1 
ATOM   284  O  O   . PRO A 1 94  ? 100.523 88.039  101.871 1.00 95.06 ? 82  PRO A O   1 
ATOM   285  C  CB  . PRO A 1 94  ? 97.349  88.551  101.685 1.00 95.06 ? 82  PRO A CB  1 
ATOM   286  C  CG  . PRO A 1 94  ? 95.990  88.043  101.914 1.00 95.06 ? 82  PRO A CG  1 
ATOM   287  C  CD  . PRO A 1 94  ? 96.125  87.264  103.174 1.00 95.06 ? 82  PRO A CD  1 
ATOM   288  N  N   . TYR A 1 95  ? 99.593  88.346  103.885 1.00 96.38 ? 83  TYR A N   1 
ATOM   289  C  CA  . TYR A 1 95  ? 100.780 88.954  104.470 1.00 96.38 ? 83  TYR A CA  1 
ATOM   290  C  C   . TYR A 1 95  ? 101.969 88.026  104.470 1.00 96.38 ? 83  TYR A C   1 
ATOM   291  O  O   . TYR A 1 95  ? 103.054 88.416  104.058 1.00 96.38 ? 83  TYR A O   1 
ATOM   292  C  CB  . TYR A 1 95  ? 100.446 89.329  105.913 1.00 96.38 ? 83  TYR A CB  1 
ATOM   293  C  CG  . TYR A 1 95  ? 101.563 89.929  106.727 1.00 96.38 ? 83  TYR A CG  1 
ATOM   294  C  CD1 . TYR A 1 95  ? 101.864 91.277  106.634 1.00 96.38 ? 83  TYR A CD1 1 
ATOM   295  C  CD2 . TYR A 1 95  ? 102.289 89.155  107.619 1.00 96.38 ? 83  TYR A CD2 1 
ATOM   296  C  CE1 . TYR A 1 95  ? 102.875 91.833  107.387 1.00 96.38 ? 83  TYR A CE1 1 
ATOM   297  C  CE2 . TYR A 1 95  ? 103.304 89.700  108.374 1.00 96.38 ? 83  TYR A CE2 1 
ATOM   298  C  CZ  . TYR A 1 95  ? 103.591 91.040  108.256 1.00 96.38 ? 83  TYR A CZ  1 
ATOM   299  O  OH  . TYR A 1 95  ? 104.599 91.588  109.009 1.00 96.38 ? 83  TYR A OH  1 
ATOM   300  N  N   . PHE A 1 96  ? 101.785 86.793  104.914 1.00 96.62 ? 84  PHE A N   1 
ATOM   301  C  CA  . PHE A 1 96  ? 102.874 85.827  104.891 1.00 96.62 ? 84  PHE A CA  1 
ATOM   302  C  C   . PHE A 1 96  ? 103.236 85.373  103.480 1.00 96.62 ? 84  PHE A C   1 
ATOM   303  O  O   . PHE A 1 96  ? 104.402 85.122  103.202 1.00 96.62 ? 84  PHE A O   1 
ATOM   304  C  CB  . PHE A 1 96  ? 102.581 84.641  105.806 1.00 96.62 ? 84  PHE A CB  1 
ATOM   305  C  CG  . PHE A 1 96  ? 102.578 84.991  107.267 1.00 96.62 ? 84  PHE A CG  1 
ATOM   306  C  CD1 . PHE A 1 96  ? 103.753 85.321  107.912 1.00 96.62 ? 84  PHE A CD1 1 
ATOM   307  C  CD2 . PHE A 1 96  ? 101.405 84.982  107.998 1.00 96.62 ? 84  PHE A CD2 1 
ATOM   308  C  CE1 . PHE A 1 96  ? 103.759 85.647  109.254 1.00 96.62 ? 84  PHE A CE1 1 
ATOM   309  C  CE2 . PHE A 1 96  ? 101.401 85.307  109.340 1.00 96.62 ? 84  PHE A CE2 1 
ATOM   310  C  CZ  . PHE A 1 96  ? 102.581 85.639  109.970 1.00 96.62 ? 84  PHE A CZ  1 
ATOM   311  N  N   . ILE A 1 97  ? 102.262 85.284  102.580 1.00 94.92 ? 85  ILE A N   1 
ATOM   312  C  CA  . ILE A 1 97  ? 102.562 84.933  101.191 1.00 94.92 ? 85  ILE A CA  1 
ATOM   313  C  C   . ILE A 1 97  ? 103.450 86.001  100.607 1.00 94.92 ? 85  ILE A C   1 
ATOM   314  O  O   . ILE A 1 97  ? 104.483 85.707  100.026 1.00 94.92 ? 85  ILE A O   1 
ATOM   315  C  CB  . ILE A 1 97  ? 101.289 84.784  100.340 1.00 94.92 ? 85  ILE A CB  1 
ATOM   316  C  CG1 . ILE A 1 97  ? 100.513 83.539  100.764 1.00 94.92 ? 85  ILE A CG1 1 
ATOM   317  C  CG2 . ILE A 1 97  ? 101.625 84.686  98.862  1.00 94.92 ? 85  ILE A CG2 1 
ATOM   318  C  CD1 . ILE A 1 97  ? 99.184  83.385  100.062 1.00 94.92 ? 85  ILE A CD1 1 
ATOM   319  N  N   . PHE A 1 98  ? 103.067 87.253  100.785 1.00 94.68 ? 86  PHE A N   1 
ATOM   320  C  CA  . PHE A 1 98  ? 103.882 88.355  100.309 1.00 94.68 ? 86  PHE A CA  1 
ATOM   321  C  C   . PHE A 1 98  ? 105.241 88.435  100.985 1.00 94.68 ? 86  PHE A C   1 
ATOM   322  O  O   . PHE A 1 98  ? 106.212 88.758  100.341 1.00 94.68 ? 86  PHE A O   1 
ATOM   323  C  CB  . PHE A 1 98  ? 103.141 89.672  100.434 1.00 94.68 ? 86  PHE A CB  1 
ATOM   324  C  CG  . PHE A 1 98  ? 102.378 90.055  99.201  1.00 94.68 ? 86  PHE A CG  1 
ATOM   325  C  CD1 . PHE A 1 98  ? 102.978 90.818  98.213  1.00 94.68 ? 86  PHE A CD1 1 
ATOM   326  C  CD2 . PHE A 1 98  ? 101.057 89.672  99.037  1.00 94.68 ? 86  PHE A CD2 1 
ATOM   327  C  CE1 . PHE A 1 98  ? 102.277 91.188  97.083  1.00 94.68 ? 86  PHE A CE1 1 
ATOM   328  C  CE2 . PHE A 1 98  ? 100.352 90.037  97.908  1.00 94.68 ? 86  PHE A CE2 1 
ATOM   329  C  CZ  . PHE A 1 98  ? 100.963 90.796  96.931  1.00 94.68 ? 86  PHE A CZ  1 
ATOM   330  N  N   . LEU A 1 99  ? 105.317 88.144  102.276 1.00 96.58 ? 87  LEU A N   1 
ATOM   331  C  CA  . LEU A 1 99  ? 106.581 88.209  102.986 1.00 96.58 ? 87  LEU A CA  1 
ATOM   332  C  C   . LEU A 1 99  ? 107.582 87.247  102.391 1.00 96.58 ? 87  LEU A C   1 
ATOM   333  O  O   . LEU A 1 99  ? 108.741 87.589  102.207 1.00 96.58 ? 87  LEU A O   1 
ATOM   334  C  CB  . LEU A 1 99  ? 106.364 87.891  104.465 1.00 96.58 ? 87  LEU A CB  1 
ATOM   335  C  CG  . LEU A 1 99  ? 107.386 87.182  105.355 1.00 96.58 ? 87  LEU A CG  1 
ATOM   336  C  CD1 . LEU A 1 99  ? 108.620 88.027  105.587 1.00 96.58 ? 87  LEU A CD1 1 
ATOM   337  C  CD2 . LEU A 1 99  ? 106.742 86.853  106.687 1.00 96.58 ? 87  LEU A CD2 1 
ATOM   338  N  N   . PHE A 1 100 ? 107.141 86.049  102.056 1.00 96.09 ? 88  PHE A N   1 
ATOM   339  C  CA  . PHE A 1 100 ? 108.064 85.056  101.547 1.00 96.09 ? 88  PHE A CA  1 
ATOM   340  C  C   . PHE A 1 100 ? 108.169 85.065  100.029 1.00 96.09 ? 88  PHE A C   1 
ATOM   341  O  O   . PHE A 1 100 ? 109.217 84.765  99.482  1.00 96.09 ? 88  PHE A O   1 
ATOM   342  C  CB  . PHE A 1 100 ? 107.695 83.672  102.067 1.00 96.09 ? 88  PHE A CB  1 
ATOM   343  C  CG  . PHE A 1 100 ? 107.928 83.504  103.537 1.00 96.09 ? 88  PHE A CG  1 
ATOM   344  C  CD1 . PHE A 1 100 ? 109.213 83.513  104.049 1.00 96.09 ? 88  PHE A CD1 1 
ATOM   345  C  CD2 . PHE A 1 100 ? 106.868 83.338  104.407 1.00 96.09 ? 88  PHE A CD2 1 
ATOM   346  C  CE1 . PHE A 1 100 ? 109.436 83.363  105.401 1.00 96.09 ? 88  PHE A CE1 1 
ATOM   347  C  CE2 . PHE A 1 100 ? 107.082 83.185  105.761 1.00 96.09 ? 88  PHE A CE2 1 
ATOM   348  C  CZ  . PHE A 1 100 ? 108.369 83.197  106.259 1.00 96.09 ? 88  PHE A CZ  1 
ATOM   349  N  N   . GLY A 1 101 ? 107.094 85.423  99.344  1.00 94.83 ? 89  GLY A N   1 
ATOM   350  C  CA  . GLY A 1 101 ? 107.134 85.453  97.896  1.00 94.83 ? 89  GLY A CA  1 
ATOM   351  C  C   . GLY A 1 101 ? 107.595 86.738  97.259  1.00 94.83 ? 89  GLY A C   1 
ATOM   352  O  O   . GLY A 1 101 ? 108.155 86.715  96.174  1.00 94.83 ? 89  GLY A O   1 
ATOM   353  N  N   . SER A 1 102 ? 107.358 87.866  97.914  1.00 94.89 ? 90  SER A N   1 
ATOM   354  C  CA  . SER A 1 102 ? 107.825 89.133  97.381  1.00 94.89 ? 90  SER A CA  1 
ATOM   355  C  C   . SER A 1 102 ? 108.679 89.939  98.330  1.00 94.89 ? 90  SER A C   1 
ATOM   356  O  O   . SER A 1 102 ? 109.735 90.409  97.954  1.00 94.89 ? 90  SER A O   1 
ATOM   357  C  CB  . SER A 1 102 ? 106.626 89.972  96.964  1.00 94.89 ? 90  SER A CB  1 
ATOM   358  O  OG  . SER A 1 102 ? 105.800 89.269  96.056  1.00 94.89 ? 90  SER A OG  1 
ATOM   359  N  N   . GLY A 1 103 ? 108.237 90.101  99.563  1.00 95.82 ? 91  GLY A N   1 
ATOM   360  C  CA  . GLY A 1 103 ? 108.952 90.941  100.505 1.00 95.82 ? 91  GLY A CA  1 
ATOM   361  C  C   . GLY A 1 103 ? 110.406 90.636  100.736 1.00 95.82 ? 91  GLY A C   1 
ATOM   362  O  O   . GLY A 1 103 ? 111.251 91.495  100.540 1.00 95.82 ? 91  GLY A O   1 
ATOM   363  N  N   . LEU A 1 104 ? 110.701 89.425  101.173 1.00 96.83 ? 92  LEU A N   1 
ATOM   364  C  CA  . LEU A 1 104 ? 112.077 89.033  101.435 1.00 96.83 ? 92  LEU A CA  1 
ATOM   365  C  C   . LEU A 1 104 ? 112.953 89.011  100.179 1.00 96.83 ? 92  LEU A C   1 
ATOM   366  O  O   . LEU A 1 104 ? 114.086 89.480  100.222 1.00 96.83 ? 92  LEU A O   1 
ATOM   367  C  CB  . LEU A 1 104 ? 112.153 87.715  102.213 1.00 96.83 ? 92  LEU A CB  1 
ATOM   368  C  CG  . LEU A 1 104 ? 112.040 87.793  103.731 1.00 96.83 ? 92  LEU A CG  1 
ATOM   369  C  CD1 . LEU A 1 104 ? 112.087 86.394  104.320 1.00 96.83 ? 92  LEU A CD1 1 
ATOM   370  C  CD2 . LEU A 1 104 ? 113.172 88.642  104.278 1.00 96.83 ? 92  LEU A CD2 1 
ATOM   371  N  N   . PRO A 1 105 ? 112.434 88.480  99.051  1.00 97.36 ? 93  PRO A N   1 
ATOM   372  C  CA  . PRO A 1 105 ? 113.252 88.548  97.841  1.00 97.36 ? 93  PRO A CA  1 
ATOM   373  C  C   . PRO A 1 105 ? 113.559 89.951  97.340  1.00 97.36 ? 93  PRO A C   1 
ATOM   374  O  O   . PRO A 1 105 ? 114.691 90.186  96.946  1.00 97.36 ? 93  PRO A O   1 
ATOM   375  C  CB  . PRO A 1 105 ? 112.405 87.791  96.831  1.00 97.36 ? 93  PRO A CB  1 
ATOM   376  C  CG  . PRO A 1 105 ? 111.742 86.749  97.647  1.00 97.36 ? 93  PRO A CG  1 
ATOM   377  C  CD  . PRO A 1 105 ? 111.364 87.474  98.901  1.00 97.36 ? 93  PRO A CD  1 
ATOM   378  N  N   . VAL A 1 106 ? 112.592 90.859  97.346  1.00 97.22 ? 94  VAL A N   1 
ATOM   379  C  CA  . VAL A 1 106 ? 112.839 92.244  96.953  1.00 97.22 ? 94  VAL A CA  1 
ATOM   380  C  C   . VAL A 1 106 ? 113.798 92.940  97.915  1.00 97.22 ? 94  VAL A C   1 
ATOM   381  O  O   . VAL A 1 106 ? 114.653 93.707  97.489  1.00 97.22 ? 94  VAL A O   1 
ATOM   382  C  CB  . VAL A 1 106 ? 111.525 93.032  96.764  1.00 97.22 ? 94  VAL A CB  1 
ATOM   383  C  CG1 . VAL A 1 106 ? 111.803 94.472  96.364  1.00 97.22 ? 94  VAL A CG1 1 
ATOM   384  C  CG2 . VAL A 1 106 ? 110.673 92.381  95.691  1.00 97.22 ? 94  VAL A CG2 1 
ATOM   385  N  N   . PHE A 1 107 ? 113.669 92.670  99.208  1.00 97.50 ? 95  PHE A N   1 
ATOM   386  C  CA  . PHE A 1 107 ? 114.566 93.244  100.214 1.00 97.50 ? 95  PHE A CA  1 
ATOM   387  C  C   . PHE A 1 107 ? 115.983 92.867  99.881  1.00 97.50 ? 95  PHE A C   1 
ATOM   388  O  O   . PHE A 1 107 ? 116.851 93.726  99.771  1.00 97.50 ? 95  PHE A O   1 
ATOM   389  C  CB  . PHE A 1 107 ? 114.167 92.707  101.587 1.00 97.50 ? 95  PHE A CB  1 
ATOM   390  C  CG  . PHE A 1 107 ? 114.998 93.208  102.727 1.00 97.50 ? 95  PHE A CG  1 
ATOM   391  C  CD1 . PHE A 1 107 ? 115.405 94.524  102.793 1.00 97.50 ? 95  PHE A CD1 1 
ATOM   392  C  CD2 . PHE A 1 107 ? 115.328 92.358  103.767 1.00 97.50 ? 95  PHE A CD2 1 
ATOM   393  C  CE1 . PHE A 1 107 ? 116.161 94.972  103.857 1.00 97.50 ? 95  PHE A CE1 1 
ATOM   394  C  CE2 . PHE A 1 107 ? 116.077 92.802  104.835 1.00 97.50 ? 95  PHE A CE2 1 
ATOM   395  C  CZ  . PHE A 1 107 ? 116.497 94.113  104.880 1.00 97.50 ? 95  PHE A CZ  1 
ATOM   396  N  N   . PHE A 1 108 ? 116.219 91.583  99.682  1.00 97.98 ? 96  PHE A N   1 
ATOM   397  C  CA  . PHE A 1 108 ? 117.546 91.117  99.345  1.00 97.98 ? 96  PHE A CA  1 
ATOM   398  C  C   . PHE A 1 108 ? 118.010 91.693  98.023  1.00 97.98 ? 96  PHE A C   1 
ATOM   399  O  O   . PHE A 1 108 ? 119.162 92.066  97.892  1.00 97.98 ? 96  PHE A O   1 
ATOM   400  C  CB  . PHE A 1 108 ? 117.567 89.592  99.315  1.00 97.98 ? 96  PHE A CB  1 
ATOM   401  C  CG  . PHE A 1 108 ? 118.885 89.010  98.918  1.00 97.98 ? 96  PHE A CG  1 
ATOM   402  C  CD1 . PHE A 1 108 ? 120.026 89.290  99.643  1.00 97.98 ? 96  PHE A CD1 1 
ATOM   403  C  CD2 . PHE A 1 108 ? 118.980 88.170  97.824  1.00 97.98 ? 96  PHE A CD2 1 
ATOM   404  C  CE1 . PHE A 1 108 ? 121.240 88.756  99.277  1.00 97.98 ? 96  PHE A CE1 1 
ATOM   405  C  CE2 . PHE A 1 108 ? 120.191 87.627  97.456  1.00 97.98 ? 96  PHE A CE2 1 
ATOM   406  C  CZ  . PHE A 1 108 ? 121.322 87.918  98.187  1.00 97.98 ? 96  PHE A CZ  1 
ATOM   407  N  N   . LEU A 1 109 ? 117.113 91.792  97.050  1.00 98.11 ? 97  LEU A N   1 
ATOM   408  C  CA  . LEU A 1 109 ? 117.449 92.364  95.749  1.00 98.11 ? 97  LEU A CA  1 
ATOM   409  C  C   . LEU A 1 109 ? 117.987 93.762  95.898  1.00 98.11 ? 97  LEU A C   1 
ATOM   410  O  O   . LEU A 1 109 ? 119.023 94.091  95.353  1.00 98.11 ? 97  LEU A O   1 
ATOM   411  C  CB  . LEU A 1 109 ? 116.218 92.398  94.852  1.00 98.11 ? 97  LEU A CB  1 
ATOM   412  C  CG  . LEU A 1 109 ? 116.351 92.877  93.414  1.00 98.11 ? 97  LEU A CG  1 
ATOM   413  C  CD1 . LEU A 1 109 ? 117.360 92.006  92.696  1.00 98.11 ? 97  LEU A CD1 1 
ATOM   414  C  CD2 . LEU A 1 109 ? 115.003 92.826  92.718  1.00 98.11 ? 97  LEU A CD2 1 
ATOM   415  N  N   . GLU A 1 110 ? 117.286 94.601  96.644  1.00 98.09 ? 98  GLU A N   1 
ATOM   416  C  CA  . GLU A 1 110 ? 117.711 95.981  96.808  1.00 98.09 ? 98  GLU A CA  1 
ATOM   417  C  C   . GLU A 1 110 ? 119.050 96.087  97.510  1.00 98.09 ? 98  GLU A C   1 
ATOM   418  O  O   . GLU A 1 110 ? 119.903 96.858  97.093  1.00 98.09 ? 98  GLU A O   1 
ATOM   419  C  CB  . GLU A 1 110 ? 116.638 96.784  97.519  1.00 98.09 ? 98  GLU A CB  1 
ATOM   420  C  CG  . GLU A 1 110 ? 115.370 96.908  96.699  1.00 98.09 ? 98  GLU A CG  1 
ATOM   421  C  CD  . GLU A 1 110 ? 114.412 97.936  97.249  1.00 98.09 ? 98  GLU A CD  1 
ATOM   422  O  OE1 . GLU A 1 110 ? 113.221 97.866  96.898  1.00 98.09 ? 98  GLU A OE1 1 
ATOM   423  O  OE2 . GLU A 1 110 ? 114.843 98.810  98.026  1.00 98.09 ? 98  GLU A OE2 1 
ATOM   424  N  N   . ILE A 1 111 ? 119.262 95.289  98.547  1.00 98.27 ? 99  ILE A N   1 
ATOM   425  C  CA  . ILE A 1 111 ? 120.547 95.293  99.222  1.00 98.27 ? 99  ILE A CA  1 
ATOM   426  C  C   . ILE A 1 111 ? 121.665 94.853  98.273  1.00 98.27 ? 99  ILE A C   1 
ATOM   427  O  O   . ILE A 1 111 ? 122.714 95.483  98.232  1.00 98.27 ? 99  ILE A O   1 
ATOM   428  C  CB  . ILE A 1 111 ? 120.523 94.412  100.483 1.00 98.27 ? 99  ILE A CB  1 
ATOM   429  C  CG1 . ILE A 1 111 ? 119.479 94.924  101.472 1.00 98.27 ? 99  ILE A CG1 1 
ATOM   430  C  CG2 . ILE A 1 111 ? 121.886 94.376  101.152 1.00 98.27 ? 99  ILE A CG2 1 
ATOM   431  C  CD1 . ILE A 1 111 ? 119.930 96.126  102.267 1.00 98.27 ? 99  ILE A CD1 1 
ATOM   432  N  N   . ILE A 1 112 ? 121.446 93.814  97.472  1.00 97.61 ? 100 ILE A N   1 
ATOM   433  C  CA  . ILE A 1 112 ? 122.526 93.348  96.610  1.00 97.61 ? 100 ILE A CA  1 
ATOM   434  C  C   . ILE A 1 112 ? 122.751 94.211  95.400  1.00 97.61 ? 100 ILE A C   1 
ATOM   435  O  O   . ILE A 1 112 ? 123.878 94.313  94.944  1.00 97.61 ? 100 ILE A O   1 
ATOM   436  C  CB  . ILE A 1 112 ? 122.388 91.905  96.118  1.00 97.61 ? 100 ILE A CB  1 
ATOM   437  C  CG1 . ILE A 1 112 ? 122.273 90.954  97.304  1.00 97.61 ? 100 ILE A CG1 1 
ATOM   438  C  CG2 . ILE A 1 112 ? 123.495 91.594  95.143  1.00 97.61 ? 100 ILE A CG2 1 
ATOM   439  C  CD1 . ILE A 1 112 ? 123.426 90.978  98.258  1.00 97.61 ? 100 ILE A CD1 1 
ATOM   440  N  N   . ILE A 1 113 ? 121.704 94.808  94.841  1.00 96.95 ? 101 ILE A N   1 
ATOM   441  C  CA  . ILE A 1 113 ? 121.985 95.717  93.740  1.00 96.95 ? 101 ILE A CA  1 
ATOM   442  C  C   . ILE A 1 113 ? 122.900 96.800  94.266  1.00 96.95 ? 101 ILE A C   1 
ATOM   443  O  O   . ILE A 1 113 ? 123.912 97.107  93.648  1.00 96.95 ? 101 ILE A O   1 
ATOM   444  C  CB  . ILE A 1 113 ? 120.701 96.347  93.173  1.00 96.95 ? 101 ILE A CB  1 
ATOM   445  C  CG1 . ILE A 1 113 ? 119.856 95.299  92.458  1.00 96.95 ? 101 ILE A CG1 1 
ATOM   446  C  CG2 . ILE A 1 113 ? 121.027 97.453  92.185  1.00 96.95 ? 101 ILE A CG2 1 
ATOM   447  C  CD1 . ILE A 1 113 ? 118.550 95.851  91.933  1.00 96.95 ? 101 ILE A CD1 1 
ATOM   448  N  N   . GLY A 1 114 ? 122.567 97.365  95.421  1.00 97.29 ? 102 GLY A N   1 
ATOM   449  C  CA  . GLY A 1 114 ? 123.405 98.380  96.024  1.00 97.29 ? 102 GLY A CA  1 
ATOM   450  C  C   . GLY A 1 114 ? 124.815 97.905  96.303  1.00 97.29 ? 102 GLY A C   1 
ATOM   451  O  O   . GLY A 1 114 ? 125.751 98.657  96.123  1.00 97.29 ? 102 GLY A O   1 
ATOM   452  N  N   . GLN A 1 115 ? 124.975 96.664  96.743  1.00 96.08 ? 103 GLN A N   1 
ATOM   453  C  CA  . GLN A 1 115 ? 126.291 96.128  97.059  1.00 96.08 ? 103 GLN A CA  1 
ATOM   454  C  C   . GLN A 1 115 ? 127.097 95.860  95.805  1.00 96.08 ? 103 GLN A C   1 
ATOM   455  O  O   . GLN A 1 115 ? 128.287 96.164  95.752  1.00 96.08 ? 103 GLN A O   1 
ATOM   456  C  CB  . GLN A 1 115 ? 126.111 94.843  97.863  1.00 96.08 ? 103 GLN A CB  1 
ATOM   457  C  CG  . GLN A 1 115 ? 127.370 94.158  98.345  1.00 96.08 ? 103 GLN A CG  1 
ATOM   458  C  CD  . GLN A 1 115 ? 127.051 93.083  99.362  1.00 96.08 ? 103 GLN A CD  1 
ATOM   459  O  OE1 . GLN A 1 115 ? 126.032 93.154  100.044 1.00 96.08 ? 103 GLN A OE1 1 
ATOM   460  N  NE2 . GLN A 1 115 ? 127.915 92.085  99.470  1.00 96.08 ? 103 GLN A NE2 1 
ATOM   461  N  N   . TYR A 1 116 ? 126.458 95.294  94.790  1.00 94.24 ? 104 TYR A N   1 
ATOM   462  C  CA  . TYR A 1 116 ? 127.135 94.998  93.538  1.00 94.24 ? 104 TYR A CA  1 
ATOM   463  C  C   . TYR A 1 116 ? 127.588 96.261  92.845  1.00 94.24 ? 104 TYR A C   1 
ATOM   464  O  O   . TYR A 1 116 ? 128.711 96.334  92.355  1.00 94.24 ? 104 TYR A O   1 
ATOM   465  C  CB  . TYR A 1 116 ? 126.148 94.267  92.641  1.00 94.24 ? 104 TYR A CB  1 
ATOM   466  C  CG  . TYR A 1 116 ? 126.727 93.446  91.521  1.00 94.24 ? 104 TYR A CG  1 
ATOM   467  C  CD1 . TYR A 1 116 ? 127.456 92.300  91.785  1.00 94.24 ? 104 TYR A CD1 1 
ATOM   468  C  CD2 . TYR A 1 116 ? 126.495 93.786  90.197  1.00 94.24 ? 104 TYR A CD2 1 
ATOM   469  C  CE1 . TYR A 1 116 ? 127.968 91.531  90.763  1.00 94.24 ? 104 TYR A CE1 1 
ATOM   470  C  CE2 . TYR A 1 116 ? 127.004 93.021  89.167  1.00 94.24 ? 104 TYR A CE2 1 
ATOM   471  C  CZ  . TYR A 1 116 ? 127.738 91.894  89.459  1.00 94.24 ? 104 TYR A CZ  1 
ATOM   472  O  OH  . TYR A 1 116 ? 128.246 91.120  88.445  1.00 94.24 ? 104 TYR A OH  1 
ATOM   473  N  N   . THR A 1 117 ? 126.722 97.267  92.806  1.00 93.35 ? 105 THR A N   1 
ATOM   474  C  CA  . THR A 1 117 ? 127.042 98.501  92.098  1.00 93.35 ? 105 THR A CA  1 
ATOM   475  C  C   . THR A 1 117 ? 127.689 99.559  92.968  1.00 93.35 ? 105 THR A C   1 
ATOM   476  O  O   . THR A 1 117 ? 128.167 100.561 92.443  1.00 93.35 ? 105 THR A O   1 
ATOM   477  C  CB  . THR A 1 117 ? 125.775 99.104  91.469  1.00 93.35 ? 105 THR A CB  1 
ATOM   478  O  OG1 . THR A 1 117 ? 124.854 99.475  92.501  1.00 93.35 ? 105 THR A OG1 1 
ATOM   479  C  CG2 . THR A 1 117 ? 125.113 98.100  90.541  1.00 93.35 ? 105 THR A CG2 1 
ATOM   480  N  N   . SER A 1 118 ? 127.674 99.367  94.285  1.00 93.62 ? 106 SER A N   1 
ATOM   481  C  CA  . SER A 1 118 ? 128.198 100.369 95.224  1.00 93.62 ? 106 SER A CA  1 
ATOM   482  C  C   . SER A 1 118 ? 127.531 101.718 95.037  1.00 93.62 ? 106 SER A C   1 
ATOM   483  O  O   . SER A 1 118 ? 128.158 102.750 95.249  1.00 93.62 ? 106 SER A O   1 
ATOM   484  C  CB  . SER A 1 118 ? 129.719 100.476 95.158  1.00 93.62 ? 106 SER A CB  1 
ATOM   485  O  OG  . SER A 1 118 ? 130.326 99.275  95.599  1.00 93.62 ? 106 SER A OG  1 
ATOM   486  N  N   . GLU A 1 119 ? 126.254 101.718 94.663  1.00 93.84 ? 107 GLU A N   1 
ATOM   487  C  CA  . GLU A 1 119 ? 125.546 102.970 94.391  1.00 93.84 ? 107 GLU A CA  1 
ATOM   488  C  C   . GLU A 1 119 ? 124.151 103.041 94.986  1.00 93.84 ? 107 GLU A C   1 
ATOM   489  O  O   . GLU A 1 119 ? 123.560 102.018 95.309  1.00 93.84 ? 107 GLU A O   1 
ATOM   490  C  CB  . GLU A 1 119 ? 125.452 103.226 92.884  1.00 93.84 ? 107 GLU A CB  1 
ATOM   491  C  CG  . GLU A 1 119 ? 126.755 103.603 92.198  1.00 93.84 ? 107 GLU A CG  1 
ATOM   492  C  CD  . GLU A 1 119 ? 127.314 104.930 92.673  1.00 93.84 ? 107 GLU A CD  1 
ATOM   493  O  OE1 . GLU A 1 119 ? 126.521 105.826 93.031  1.00 93.84 ? 107 GLU A OE1 1 
ATOM   494  O  OE2 . GLU A 1 119 ? 128.553 105.082 92.676  1.00 93.84 ? 107 GLU A OE2 1 
ATOM   495  N  N   . GLY A 1 120 ? 123.626 104.252 95.138  1.00 94.55 ? 108 GLY A N   1 
ATOM   496  C  CA  . GLY A 1 120 ? 122.277 104.434 95.656  1.00 94.55 ? 108 GLY A CA  1 
ATOM   497  C  C   . GLY A 1 120 ? 121.208 104.211 94.610  1.00 94.55 ? 108 GLY A C   1 
ATOM   498  O  O   . GLY A 1 120 ? 121.531 103.876 93.482  1.00 94.55 ? 108 GLY A O   1 
ATOM   499  N  N   . GLY A 1 121 ? 119.948 104.382 94.990  1.00 94.64 ? 109 GLY A N   1 
ATOM   500  C  CA  . GLY A 1 121 ? 118.840 104.120 94.083  1.00 94.64 ? 109 GLY A CA  1 
ATOM   501  C  C   . GLY A 1 121 ? 118.868 104.687 92.683  1.00 94.64 ? 109 GLY A C   1 
ATOM   502  O  O   . GLY A 1 121 ? 118.787 103.942 91.714  1.00 94.64 ? 109 GLY A O   1 
ATOM   503  N  N   . ILE A 1 122 ? 118.953 106.001 92.556  1.00 96.95 ? 110 ILE A N   1 
ATOM   504  C  CA  . ILE A 1 122 ? 118.887 106.601 91.232  1.00 96.95 ? 110 ILE A CA  1 
ATOM   505  C  C   . ILE A 1 122 ? 120.040 106.185 90.336  1.00 96.95 ? 110 ILE A C   1 
ATOM   506  O  O   . ILE A 1 122 ? 119.831 105.873 89.169  1.00 96.95 ? 110 ILE A O   1 
ATOM   507  C  CB  . ILE A 1 122 ? 118.804 108.132 91.329  1.00 96.95 ? 110 ILE A CB  1 
ATOM   508  C  CG1 . ILE A 1 122 ? 117.807 108.527 92.415  1.00 96.95 ? 110 ILE A CG1 1 
ATOM   509  C  CG2 . ILE A 1 122 ? 118.405 108.732 89.992  1.00 96.95 ? 110 ILE A CG2 1 
ATOM   510  C  CD1 . ILE A 1 122 ? 117.629 110.016 92.564  1.00 96.95 ? 110 ILE A CD1 1 
ATOM   511  N  N   . THR A 1 123 ? 121.247 106.136 90.882  1.00 95.17 ? 111 THR A N   1 
ATOM   512  C  CA  . THR A 1 123 ? 122.417 105.811 90.073  1.00 95.17 ? 111 THR A CA  1 
ATOM   513  C  C   . THR A 1 123 ? 122.607 104.321 89.816  1.00 95.17 ? 111 THR A C   1 
ATOM   514  O  O   . THR A 1 123 ? 123.138 103.941 88.776  1.00 95.17 ? 111 THR A O   1 
ATOM   515  C  CB  . THR A 1 123 ? 123.698 106.376 90.697  1.00 95.17 ? 111 THR A CB  1 
ATOM   516  O  OG1 . THR A 1 123 ? 123.706 106.092 92.100  1.00 95.17 ? 111 THR A OG1 1 
ATOM   517  C  CG2 . THR A 1 123 ? 123.759 107.877 90.500  1.00 95.17 ? 111 THR A CG2 1 
ATOM   518  N  N   . CYS A 1 124 ? 122.185 103.479 90.753  1.00 96.09 ? 112 CYS A N   1 
ATOM   519  C  CA  . CYS A 1 124 ? 122.322 102.033 90.577  1.00 96.09 ? 112 CYS A CA  1 
ATOM   520  C  C   . CYS A 1 124 ? 121.473 101.524 89.437  1.00 96.09 ? 112 CYS A C   1 
ATOM   521  O  O   . CYS A 1 124 ? 121.908 100.672 88.671  1.00 96.09 ? 112 CYS A O   1 
ATOM   522  C  CB  . CYS A 1 124 ? 121.962 101.260 91.844  1.00 96.09 ? 112 CYS A CB  1 
ATOM   523  S  SG  . CYS A 1 124 ? 120.196 101.050 92.154  1.00 96.09 ? 112 CYS A SG  1 
ATOM   524  N  N   . TRP A 1 125 ? 120.258 102.042 89.320  1.00 97.15 ? 113 TRP A N   1 
ATOM   525  C  CA  . TRP A 1 125 ? 119.364 101.579 88.276  1.00 97.15 ? 113 TRP A CA  1 
ATOM   526  C  C   . TRP A 1 125 ? 119.931 101.886 86.929  1.00 97.15 ? 113 TRP A C   1 
ATOM   527  O  O   . TRP A 1 125 ? 119.826 101.084 86.021  1.00 97.15 ? 113 TRP A O   1 
ATOM   528  C  CB  . TRP A 1 125 ? 117.938 102.085 88.453  1.00 97.15 ? 113 TRP A CB  1 
ATOM   529  C  CG  . TRP A 1 125 ? 117.179 101.137 89.294  1.00 97.15 ? 113 TRP A CG  1 
ATOM   530  C  CD1 . TRP A 1 125 ? 116.659 101.372 90.523  1.00 97.15 ? 113 TRP A CD1 1 
ATOM   531  C  CD2 . TRP A 1 125 ? 116.909 99.760  88.997  1.00 97.15 ? 113 TRP A CD2 1 
ATOM   532  N  NE1 . TRP A 1 125 ? 116.054 100.237 91.007  1.00 97.15 ? 113 TRP A NE1 1 
ATOM   533  C  CE2 . TRP A 1 125 ? 116.195 99.233  90.086  1.00 97.15 ? 113 TRP A CE2 1 
ATOM   534  C  CE3 . TRP A 1 125 ? 117.187 98.929  87.907  1.00 97.15 ? 113 TRP A CE3 1 
ATOM   535  C  CZ2 . TRP A 1 125 ? 115.759 97.915  90.120  1.00 97.15 ? 113 TRP A CZ2 1 
ATOM   536  C  CZ3 . TRP A 1 125 ? 116.754 97.622  87.945  1.00 97.15 ? 113 TRP A CZ3 1 
ATOM   537  C  CH2 . TRP A 1 125 ? 116.046 97.127  89.041  1.00 97.15 ? 113 TRP A CH2 1 
ATOM   538  N  N   . GLU A 1 126 ? 120.569 103.034 86.808  1.00 93.26 ? 114 GLU A N   1 
ATOM   539  C  CA  . GLU A 1 126 ? 121.171 103.403 85.550  1.00 93.26 ? 114 GLU A CA  1 
ATOM   540  C  C   . GLU A 1 126 ? 122.246 102.405 85.145  1.00 93.26 ? 114 GLU A C   1 
ATOM   541  O  O   . GLU A 1 126 ? 122.360 102.072 83.972  1.00 93.26 ? 114 GLU A O   1 
ATOM   542  C  CB  . GLU A 1 126 ? 121.738 104.812 85.648  1.00 93.26 ? 114 GLU A CB  1 
ATOM   543  C  CG  . GLU A 1 126 ? 120.691 105.868 85.952  1.00 93.26 ? 114 GLU A CG  1 
ATOM   544  C  CD  . GLU A 1 126 ? 121.298 107.179 86.407  1.00 93.26 ? 114 GLU A CD  1 
ATOM   545  O  OE1 . GLU A 1 126 ? 120.531 108.098 86.761  1.00 93.26 ? 114 GLU A OE1 1 
ATOM   546  O  OE2 . GLU A 1 126 ? 122.542 107.287 86.416  1.00 93.26 ? 114 GLU A OE2 1 
ATOM   547  N  N   . LYS A 1 127 ? 123.058 101.940 86.083  1.00 91.59 ? 115 LYS A N   1 
ATOM   548  C  CA  . LYS A 1 127 ? 124.030 100.905 85.739  1.00 91.59 ? 115 LYS A CA  1 
ATOM   549  C  C   . LYS A 1 127 ? 123.427 99.555  85.342  1.00 91.59 ? 115 LYS A C   1 
ATOM   550  O  O   . LYS A 1 127 ? 123.862 98.951  84.366  1.00 91.59 ? 115 LYS A O   1 
ATOM   551  C  CB  . LYS A 1 127 ? 125.006 100.693 86.888  1.00 91.59 ? 115 LYS A CB  1 
ATOM   552  C  CG  . LYS A 1 127 ? 125.832 101.917 87.217  1.00 91.59 ? 115 LYS A CG  1 
ATOM   553  C  CD  . LYS A 1 127 ? 126.887 101.576 88.247  1.00 91.59 ? 115 LYS A CD  1 
ATOM   554  C  CE  . LYS A 1 127 ? 127.863 100.540 87.724  1.00 91.59 ? 115 LYS A CE  1 
ATOM   555  N  NZ  . LYS A 1 127 ? 128.852 100.156 88.767  1.00 91.59 ? 115 LYS A NZ  1 
ATOM   556  N  N   . ILE A 1 128 ? 122.445 99.072  86.103  1.00 93.76 ? 116 ILE A N   1 
ATOM   557  C  CA  . ILE A 1 128 ? 121.822 97.787  85.792  1.00 93.76 ? 116 ILE A CA  1 
ATOM   558  C  C   . ILE A 1 128 ? 121.047 97.827  84.489  1.00 93.76 ? 116 ILE A C   1 
ATOM   559  O  O   . ILE A 1 128 ? 121.234 96.975  83.624  1.00 93.76 ? 116 ILE A O   1 
ATOM   560  C  CB  . ILE A 1 128 ? 120.857 97.373  86.921  1.00 93.76 ? 116 ILE A CB  1 
ATOM   561  C  CG1 . ILE A 1 128 ? 121.603 97.254  88.248  1.00 93.76 ? 116 ILE A CG1 1 
ATOM   562  C  CG2 . ILE A 1 128 ? 120.171 96.057  86.596  1.00 93.76 ? 116 ILE A CG2 1 
ATOM   563  C  CD1 . ILE A 1 128 ? 122.585 96.105  88.289  1.00 93.76 ? 116 ILE A CD1 1 
ATOM   564  N  N   . CYS A 1 129 ? 120.207 98.839  84.322  1.00 95.35 ? 117 CYS A N   1 
ATOM   565  C  CA  . CYS A 1 129 ? 119.466 99.006  83.082  1.00 95.35 ? 117 CYS A CA  1 
ATOM   566  C  C   . CYS A 1 129 ? 119.219 100.481 82.927  1.00 95.35 ? 117 CYS A C   1 
ATOM   567  O  O   . CYS A 1 129 ? 118.425 101.056 83.661  1.00 95.35 ? 117 CYS A O   1 
ATOM   568  C  CB  . CYS A 1 129 ? 118.139 98.260  83.113  1.00 95.35 ? 117 CYS A CB  1 
ATOM   569  S  SG  . CYS A 1 129 ? 117.239 98.311  81.548  1.00 95.35 ? 117 CYS A SG  1 
ATOM   570  N  N   . PRO A 1 130 ? 119.837 101.093 81.927  1.00 94.49 ? 118 PRO A N   1 
ATOM   571  C  CA  . PRO A 1 130 ? 119.714 102.536 81.762  1.00 94.49 ? 118 PRO A CA  1 
ATOM   572  C  C   . PRO A 1 130 ? 118.294 103.047 81.523  1.00 94.49 ? 118 PRO A C   1 
ATOM   573  O  O   . PRO A 1 130 ? 118.014 104.091 82.026  1.00 94.49 ? 118 PRO A O   1 
ATOM   574  C  CB  . PRO A 1 130 ? 120.600 102.811 80.556  1.00 94.49 ? 118 PRO A CB  1 
ATOM   575  C  CG  . PRO A 1 130 ? 121.639 101.754 80.613  1.00 94.49 ? 118 PRO A CG  1 
ATOM   576  C  CD  . PRO A 1 130 ? 120.953 100.536 81.151  1.00 94.49 ? 118 PRO A CD  1 
ATOM   577  N  N   . LEU A 1 131 ? 117.474 102.357 80.743  1.00 96.73 ? 119 LEU A N   1 
ATOM   578  C  CA  . LEU A 1 131 ? 116.128 102.824 80.410  1.00 96.73 ? 119 LEU A CA  1 
ATOM   579  C  C   . LEU A 1 131 ? 115.231 102.839 81.627  1.00 96.73 ? 119 LEU A C   1 
ATOM   580  O  O   . LEU A 1 131 ? 114.202 103.509 81.641  1.00 96.73 ? 119 LEU A O   1 
ATOM   581  C  CB  . LEU A 1 131 ? 115.539 101.887 79.351  1.00 96.73 ? 119 LEU A CB  1 
ATOM   582  C  CG  . LEU A 1 131 ? 114.268 102.220 78.580  1.00 96.73 ? 119 LEU A CG  1 
ATOM   583  C  CD1 . LEU A 1 131 ? 114.476 103.466 77.740  1.00 96.73 ? 119 LEU A CD1 1 
ATOM   584  C  CD2 . LEU A 1 131 ? 113.901 101.043 77.693  1.00 96.73 ? 119 LEU A CD2 1 
ATOM   585  N  N   . PHE A 1 132 ? 115.625 102.126 82.669  1.00 97.70 ? 120 PHE A N   1 
ATOM   586  C  CA  . PHE A 1 132 ? 114.782 102.002 83.855  1.00 97.70 ? 120 PHE A CA  1 
ATOM   587  C  C   . PHE A 1 132 ? 115.266 102.814 85.039  1.00 97.70 ? 120 PHE A C   1 
ATOM   588  O  O   . PHE A 1 132 ? 115.011 102.457 86.181  1.00 97.70 ? 120 PHE A O   1 
ATOM   589  C  CB  . PHE A 1 132 ? 114.562 100.538 84.212  1.00 97.70 ? 120 PHE A CB  1 
ATOM   590  C  CG  . PHE A 1 132 ? 113.522 99.868  83.364  1.00 97.70 ? 120 PHE A CG  1 
ATOM   591  C  CD1 . PHE A 1 132 ? 112.188 99.907  83.727  1.00 97.70 ? 120 PHE A CD1 1 
ATOM   592  C  CD2 . PHE A 1 132 ? 113.875 99.215  82.198  1.00 97.70 ? 120 PHE A CD2 1 
ATOM   593  C  CE1 . PHE A 1 132 ? 111.228 99.297  82.947  1.00 97.70 ? 120 PHE A CE1 1 
ATOM   594  C  CE2 . PHE A 1 132 ? 112.921 98.603  81.412  1.00 97.70 ? 120 PHE A CE2 1 
ATOM   595  C  CZ  . PHE A 1 132 ? 111.594 98.644  81.788  1.00 97.70 ? 120 PHE A CZ  1 
ATOM   596  N  N   . SER A 1 133 ? 115.977 103.899 84.770  1.00 96.95 ? 121 SER A N   1 
ATOM   597  C  CA  . SER A 1 133 ? 116.447 104.782 85.827  1.00 96.95 ? 121 SER A CA  1 
ATOM   598  C  C   . SER A 1 133 ? 115.272 105.408 86.547  1.00 96.95 ? 121 SER A C   1 
ATOM   599  O  O   . SER A 1 133 ? 115.418 105.874 87.671  1.00 96.95 ? 121 SER A O   1 
ATOM   600  C  CB  . SER A 1 133 ? 117.328 105.868 85.235  1.00 96.95 ? 121 SER A CB  1 
ATOM   601  O  OG  . SER A 1 133 ? 116.677 106.521 84.164  1.00 96.95 ? 121 SER A OG  1 
ATOM   602  N  N   . GLY A 1 134 ? 114.107 105.425 85.913  1.00 98.20 ? 122 GLY A N   1 
ATOM   603  C  CA  . GLY A 1 134 ? 112.924 106.023 86.494  1.00 98.20 ? 122 GLY A CA  1 
ATOM   604  C  C   . GLY A 1 134 ? 112.480 105.375 87.771  1.00 98.20 ? 122 GLY A C   1 
ATOM   605  O  O   . GLY A 1 134 ? 111.780 105.996 88.552  1.00 98.20 ? 122 GLY A O   1 
ATOM   606  N  N   . ILE A 1 135 ? 112.854 104.124 87.985  1.00 98.48 ? 123 ILE A N   1 
ATOM   607  C  CA  . ILE A 1 135 ? 112.526 103.451 89.232  1.00 98.48 ? 123 ILE A CA  1 
ATOM   608  C  C   . ILE A 1 135 ? 113.157 104.218 90.385  1.00 98.48 ? 123 ILE A C   1 
ATOM   609  O  O   . ILE A 1 135 ? 112.515 104.421 91.410  1.00 98.48 ? 123 ILE A O   1 
ATOM   610  C  CB  . ILE A 1 135 ? 113.030 101.994 89.215  1.00 98.48 ? 123 ILE A CB  1 
ATOM   611  C  CG1 . ILE A 1 135 ? 112.432 101.236 88.031  1.00 98.48 ? 123 ILE A CG1 1 
ATOM   612  C  CG2 . ILE A 1 135 ? 112.691 101.285 90.513  1.00 98.48 ? 123 ILE A CG2 1 
ATOM   613  C  CD1 . ILE A 1 135 ? 112.946 99.821  87.897  1.00 98.48 ? 123 ILE A CD1 1 
ATOM   614  N  N   . GLY A 1 136 ? 114.393 104.670 90.227  1.00 98.22 ? 124 GLY A N   1 
ATOM   615  C  CA  . GLY A 1 136 ? 115.025 105.483 91.252  1.00 98.22 ? 124 GLY A CA  1 
ATOM   616  C  C   . GLY A 1 136 ? 114.356 106.820 91.487  1.00 98.22 ? 124 GLY A C   1 
ATOM   617  O  O   . GLY A 1 136 ? 114.219 107.246 92.628  1.00 98.22 ? 124 GLY A O   1 
ATOM   618  N  N   . TYR A 1 137 ? 113.947 107.496 90.422  1.00 98.34 ? 125 TYR A N   1 
ATOM   619  C  CA  . TYR A 1 137 ? 113.237 108.763 90.554  1.00 98.34 ? 125 TYR A CA  1 
ATOM   620  C  C   . TYR A 1 137 ? 111.902 108.566 91.243  1.00 98.34 ? 125 TYR A C   1 
ATOM   621  O  O   . TYR A 1 137 ? 111.504 109.379 92.066  1.00 98.34 ? 125 TYR A O   1 
ATOM   622  C  CB  . TYR A 1 137 ? 113.035 109.416 89.188  1.00 98.34 ? 125 TYR A CB  1 
ATOM   623  C  CG  . TYR A 1 137 ? 114.312 109.835 88.504  1.00 98.34 ? 125 TYR A CG  1 
ATOM   624  C  CD1 . TYR A 1 137 ? 114.986 110.981 88.894  1.00 98.34 ? 125 TYR A CD1 1 
ATOM   625  C  CD2 . TYR A 1 137 ? 114.836 109.094 87.459  1.00 98.34 ? 125 TYR A CD2 1 
ATOM   626  C  CE1 . TYR A 1 137 ? 116.152 111.370 88.266  1.00 98.34 ? 125 TYR A CE1 1 
ATOM   627  C  CE2 . TYR A 1 137 ? 116.003 109.472 86.826  1.00 98.34 ? 125 TYR A CE2 1 
ATOM   628  C  CZ  . TYR A 1 137 ? 116.656 110.612 87.234  1.00 98.34 ? 125 TYR A CZ  1 
ATOM   629  O  OH  . TYR A 1 137 ? 117.819 110.995 86.607  1.00 98.34 ? 125 TYR A OH  1 
ATOM   630  N  N   . ALA A 1 138 ? 111.204 107.489 90.907  1.00 98.43 ? 126 ALA A N   1 
ATOM   631  C  CA  . ALA A 1 138 ? 109.915 107.196 91.516  1.00 98.43 ? 126 ALA A CA  1 
ATOM   632  C  C   . ALA A 1 138 ? 110.083 106.961 92.983  1.00 98.43 ? 126 ALA A C   1 
ATOM   633  O  O   . ALA A 1 138 ? 109.274 107.412 93.771  1.00 98.43 ? 126 ALA A O   1 
ATOM   634  C  CB  . ALA A 1 138 ? 109.283 105.984 90.862  1.00 98.43 ? 126 ALA A CB  1 
ATOM   635  N  N   . SER A 1 139 ? 111.149 106.271 93.360  1.00 97.75 ? 127 SER A N   1 
ATOM   636  C  CA  . SER A 1 139 ? 111.408 105.990 94.761  1.00 97.75 ? 127 SER A CA  1 
ATOM   637  C  C   . SER A 1 139 ? 111.599 107.276 95.533  1.00 97.75 ? 127 SER A C   1 
ATOM   638  O  O   . SER A 1 139 ? 111.106 107.398 96.642  1.00 97.75 ? 127 SER A O   1 
ATOM   639  C  CB  . SER A 1 139 ? 112.636 105.109 94.898  1.00 97.75 ? 127 SER A CB  1 
ATOM   640  O  OG  . SER A 1 139 ? 112.437 103.856 94.270  1.00 97.75 ? 127 SER A OG  1 
ATOM   641  N  N   . VAL A 1 140 ? 112.296 108.246 94.952  1.00 98.07 ? 128 VAL A N   1 
ATOM   642  C  CA  . VAL A 1 140 ? 112.463 109.541 95.601  1.00 98.07 ? 128 VAL A CA  1 
ATOM   643  C  C   . VAL A 1 140 ? 111.136 110.263 95.806  1.00 98.07 ? 128 VAL A C   1 
ATOM   644  O  O   . VAL A 1 140 ? 110.888 110.804 96.875  1.00 98.07 ? 128 VAL A O   1 
ATOM   645  C  CB  . VAL A 1 140 ? 113.430 110.435 94.804  1.00 98.07 ? 128 VAL A CB  1 
ATOM   646  C  CG1 . VAL A 1 140 ? 113.370 111.875 95.279  1.00 98.07 ? 128 VAL A CG1 1 
ATOM   647  C  CG2 . VAL A 1 140 ? 114.842 109.900 94.918  1.00 98.07 ? 128 VAL A CG2 1 
ATOM   648  N  N   . VAL A 1 141 ? 110.262 110.241 94.810  1.00 98.02 ? 129 VAL A N   1 
ATOM   649  C  CA  . VAL A 1 141 ? 108.957 110.877 94.942  1.00 98.02 ? 129 VAL A CA  1 
ATOM   650  C  C   . VAL A 1 141 ? 108.140 110.208 96.038  1.00 98.02 ? 129 VAL A C   1 
ATOM   651  O  O   . VAL A 1 141 ? 107.507 110.885 96.838  1.00 98.02 ? 129 VAL A O   1 
ATOM   652  C  CB  . VAL A 1 141 ? 108.191 110.870 93.603  1.00 98.02 ? 129 VAL A CB  1 
ATOM   653  C  CG1 . VAL A 1 141 ? 106.799 111.460 93.762  1.00 98.02 ? 129 VAL A CG1 1 
ATOM   654  C  CG2 . VAL A 1 141 ? 108.972 111.627 92.544  1.00 98.02 ? 129 VAL A CG2 1 
ATOM   655  N  N   . ILE A 1 142 ? 108.175 108.882 96.102  1.00 97.37 ? 130 ILE A N   1 
ATOM   656  C  CA  . ILE A 1 142 ? 107.458 108.160 97.144  1.00 97.37 ? 130 ILE A CA  1 
ATOM   657  C  C   . ILE A 1 142 ? 108.011 108.517 98.517  1.00 97.37 ? 130 ILE A C   1 
ATOM   658  O  O   . ILE A 1 142 ? 107.247 108.730 99.445  1.00 97.37 ? 130 ILE A O   1 
ATOM   659  C  CB  . ILE A 1 142 ? 107.550 106.637 96.930  1.00 97.37 ? 130 ILE A CB  1 
ATOM   660  C  CG1 . ILE A 1 142 ? 107.047 106.245 95.548  1.00 97.37 ? 130 ILE A CG1 1 
ATOM   661  C  CG2 . ILE A 1 142 ? 106.693 105.896 97.924  1.00 97.37 ? 130 ILE A CG2 1 
ATOM   662  C  CD1 . ILE A 1 142 ? 107.134 104.761 95.279  1.00 97.37 ? 130 ILE A CD1 1 
ATOM   663  N  N   . VAL A 1 143 ? 109.332 108.608 98.646  1.00 97.25 ? 131 VAL A N   1 
ATOM   664  C  CA  . VAL A 1 143 ? 109.955 108.964 99.915  1.00 97.25 ? 131 VAL A CA  1 
ATOM   665  C  C   . VAL A 1 143 ? 109.549 110.361 100.329 1.00 97.25 ? 131 VAL A C   1 
ATOM   666  O  O   . VAL A 1 143 ? 109.207 110.583 101.470 1.00 97.25 ? 131 VAL A O   1 
ATOM   667  C  CB  . VAL A 1 143 ? 111.490 108.860 99.838  1.00 97.25 ? 131 VAL A CB  1 
ATOM   668  C  CG1 . VAL A 1 143 ? 112.158 109.531 101.022 1.00 97.25 ? 131 VAL A CG1 1 
ATOM   669  C  CG2 . VAL A 1 143 ? 111.917 107.413 99.775  1.00 97.25 ? 131 VAL A CG2 1 
ATOM   670  N  N   . SER A 1 144 ? 109.503 111.289 99.386  1.00 97.66 ? 132 SER A N   1 
ATOM   671  C  CA  . SER A 1 144 ? 109.154 112.664 99.687  1.00 97.66 ? 132 SER A CA  1 
ATOM   672  C  C   . SER A 1 144 ? 107.766 112.741 100.257 1.00 97.66 ? 132 SER A C   1 
ATOM   673  O  O   . SER A 1 144 ? 107.515 113.519 101.166 1.00 97.66 ? 132 SER A O   1 
ATOM   674  C  CB  . SER A 1 144 ? 109.221 113.487 98.409  1.00 97.66 ? 132 SER A CB  1 
ATOM   675  O  OG  . SER A 1 144 ? 110.488 113.374 97.793  1.00 97.66 ? 132 SER A OG  1 
ATOM   676  N  N   . LEU A 1 145 ? 106.843 111.950 99.746  1.00 97.37 ? 133 LEU A N   1 
ATOM   677  C  CA  . LEU A 1 145 ? 105.466 111.995 100.217 1.00 97.37 ? 133 LEU A CA  1 
ATOM   678  C  C   . LEU A 1 145 ? 105.344 111.308 101.559 1.00 97.37 ? 133 LEU A C   1 
ATOM   679  O  O   . LEU A 1 145 ? 104.600 111.763 102.422 1.00 97.37 ? 133 LEU A O   1 
ATOM   680  C  CB  . LEU A 1 145 ? 104.539 111.357 99.187  1.00 97.37 ? 133 LEU A CB  1 
ATOM   681  C  CG  . LEU A 1 145 ? 104.412 112.086 97.852  1.00 97.37 ? 133 LEU A CG  1 
ATOM   682  C  CD1 . LEU A 1 145 ? 103.696 111.224 96.827  1.00 97.37 ? 133 LEU A CD1 1 
ATOM   683  C  CD2 . LEU A 1 145 ? 103.698 113.413 98.038  1.00 97.37 ? 133 LEU A CD2 1 
ATOM   684  N  N   . LEU A 1 146 ? 106.086 110.227 101.749 1.00 96.54 ? 134 LEU A N   1 
ATOM   685  C  CA  . LEU A 1 146 ? 106.059 109.492 103.002 1.00 96.54 ? 134 LEU A CA  1 
ATOM   686  C  C   . LEU A 1 146 ? 106.546 110.350 104.140 1.00 96.54 ? 134 LEU A C   1 
ATOM   687  O  O   . LEU A 1 146 ? 105.980 110.326 105.224 1.00 96.54 ? 134 LEU A O   1 
ATOM   688  C  CB  . LEU A 1 146 ? 106.932 108.242 102.889 1.00 96.54 ? 134 LEU A CB  1 
ATOM   689  C  CG  . LEU A 1 146 ? 107.284 107.466 104.159 1.00 96.54 ? 134 LEU A CG  1 
ATOM   690  C  CD1 . LEU A 1 146 ? 106.082 106.712 104.696 1.00 96.54 ? 134 LEU A CD1 1 
ATOM   691  C  CD2 . LEU A 1 146 ? 108.439 106.516 103.896 1.00 96.54 ? 134 LEU A CD2 1 
ATOM   692  N  N   . ASN A 1 147 ? 107.600 111.120 103.909 1.00 97.91 ? 135 ASN A N   1 
ATOM   693  C  CA  . ASN A 1 147 ? 108.169 111.976 104.947 1.00 97.91 ? 135 ASN A CA  1 
ATOM   694  C  C   . ASN A 1 147 ? 107.193 113.013 105.441 1.00 97.91 ? 135 ASN A C   1 
ATOM   695  O  O   . ASN A 1 147 ? 107.227 113.387 106.603 1.00 97.91 ? 135 ASN A O   1 
ATOM   696  C  CB  . ASN A 1 147 ? 109.431 112.654 104.428 1.00 97.91 ? 135 ASN A CB  1 
ATOM   697  C  CG  . ASN A 1 147 ? 110.551 111.673 104.167 1.00 97.91 ? 135 ASN A CG  1 
ATOM   698  O  OD1 . ASN A 1 147 ? 110.475 110.512 104.555 1.00 97.91 ? 135 ASN A OD1 1 
ATOM   699  N  ND2 . ASN A 1 147 ? 111.599 112.135 103.506 1.00 97.91 ? 135 ASN A ND2 1 
ATOM   700  N  N   . VAL A 1 148 ? 106.334 113.495 104.562 1.00 97.48 ? 136 VAL A N   1 
ATOM   701  C  CA  . VAL A 1 148 ? 105.322 114.464 104.951 1.00 97.48 ? 136 VAL A CA  1 
ATOM   702  C  C   . VAL A 1 148 ? 104.312 113.911 105.949 1.00 97.48 ? 136 VAL A C   1 
ATOM   703  O  O   . VAL A 1 148 ? 103.978 114.582 106.917 1.00 97.48 ? 136 VAL A O   1 
ATOM   704  C  CB  . VAL A 1 148 ? 104.585 115.009 103.705 1.00 97.48 ? 136 VAL A CB  1 
ATOM   705  C  CG1 . VAL A 1 148 ? 103.473 115.954 104.098 1.00 97.48 ? 136 VAL A CG1 1 
ATOM   706  C  CG2 . VAL A 1 148 ? 105.557 115.693 102.764 1.00 97.48 ? 136 VAL A CG2 1 
ATOM   707  N  N   . TYR A 1 149 ? 103.828 112.693 105.734 1.00 95.88 ? 137 TYR A N   1 
ATOM   708  C  CA  . TYR A 1 149 ? 102.805 112.143 106.617 1.00 95.88 ? 137 TYR A CA  1 
ATOM   709  C  C   . TYR A 1 149 ? 103.292 111.254 107.756 1.00 95.88 ? 137 TYR A C   1 
ATOM   710  O  O   . TYR A 1 149 ? 102.614 111.107 108.757 1.00 95.88 ? 137 TYR A O   1 
ATOM   711  C  CB  . TYR A 1 149 ? 101.681 111.472 105.814 1.00 95.88 ? 137 TYR A CB  1 
ATOM   712  C  CG  . TYR A 1 149 ? 102.046 110.271 104.968 1.00 95.88 ? 137 TYR A CG  1 
ATOM   713  C  CD1 . TYR A 1 149 ? 102.009 108.989 105.495 1.00 95.88 ? 137 TYR A CD1 1 
ATOM   714  C  CD2 . TYR A 1 149 ? 102.371 110.414 103.630 1.00 95.88 ? 137 TYR A CD2 1 
ATOM   715  C  CE1 . TYR A 1 149 ? 102.328 107.891 104.728 1.00 95.88 ? 137 TYR A CE1 1 
ATOM   716  C  CE2 . TYR A 1 149 ? 102.682 109.320 102.851 1.00 95.88 ? 137 TYR A CE2 1 
ATOM   717  C  CZ  . TYR A 1 149 ? 102.660 108.062 103.406 1.00 95.88 ? 137 TYR A CZ  1 
ATOM   718  O  OH  . TYR A 1 149 ? 102.968 106.968 102.636 1.00 95.88 ? 137 TYR A OH  1 
ATOM   719  N  N   . TYR A 1 150 ? 104.468 110.672 107.619 1.00 95.74 ? 138 TYR A N   1 
ATOM   720  C  CA  . TYR A 1 150 ? 105.006 109.812 108.658 1.00 95.74 ? 138 TYR A CA  1 
ATOM   721  C  C   . TYR A 1 150 ? 105.239 110.633 109.903 1.00 95.74 ? 138 TYR A C   1 
ATOM   722  O  O   . TYR A 1 150 ? 105.035 110.164 111.012 1.00 95.74 ? 138 TYR A O   1 
ATOM   723  C  CB  . TYR A 1 150 ? 106.297 109.160 108.170 1.00 95.74 ? 138 TYR A CB  1 
ATOM   724  C  CG  . TYR A 1 150 ? 106.857 108.061 109.045 1.00 95.74 ? 138 TYR A CG  1 
ATOM   725  C  CD1 . TYR A 1 150 ? 106.429 106.750 108.904 1.00 95.74 ? 138 TYR A CD1 1 
ATOM   726  C  CD2 . TYR A 1 150 ? 107.839 108.331 109.990 1.00 95.74 ? 138 TYR A CD2 1 
ATOM   727  C  CE1 . TYR A 1 150 ? 106.948 105.742 109.691 1.00 95.74 ? 138 TYR A CE1 1 
ATOM   728  C  CE2 . TYR A 1 150 ? 108.362 107.331 110.782 1.00 95.74 ? 138 TYR A CE2 1 
ATOM   729  C  CZ  . TYR A 1 150 ? 107.916 106.038 110.628 1.00 95.74 ? 138 TYR A CZ  1 
ATOM   730  O  OH  . TYR A 1 150 ? 108.440 105.039 111.414 1.00 95.74 ? 138 TYR A OH  1 
ATOM   731  N  N   . ILE A 1 151 ? 105.696 111.861 109.724 1.00 97.88 ? 139 ILE A N   1 
ATOM   732  C  CA  . ILE A 1 151 ? 105.967 112.735 110.846 1.00 97.88 ? 139 ILE A CA  1 
ATOM   733  C  C   . ILE A 1 151 ? 104.693 113.165 111.568 1.00 97.88 ? 139 ILE A C   1 
ATOM   734  O  O   . ILE A 1 151 ? 104.741 113.521 112.735 1.00 97.88 ? 139 ILE A O   1 
ATOM   735  C  CB  . ILE A 1 151 ? 106.784 113.935 110.347 1.00 97.88 ? 139 ILE A CB  1 
ATOM   736  C  CG1 . ILE A 1 151 ? 107.336 114.758 111.502 1.00 97.88 ? 139 ILE A CG1 1 
ATOM   737  C  CG2 . ILE A 1 151 ? 105.973 114.782 109.384 1.00 97.88 ? 139 ILE A CG2 1 
ATOM   738  C  CD1 . ILE A 1 151 ? 108.356 114.007 112.318 1.00 97.88 ? 139 ILE A CD1 1 
ATOM   739  N  N   . VAL A 1 152 ? 103.550 113.124 110.894 1.00 97.84 ? 140 VAL A N   1 
ATOM   740  C  CA  . VAL A 1 152 ? 102.274 113.459 111.532 1.00 97.84 ? 140 VAL A CA  1 
ATOM   741  C  C   . VAL A 1 152 ? 101.934 112.470 112.644 1.00 97.84 ? 140 VAL A C   1 
ATOM   742  O  O   . VAL A 1 152 ? 101.403 112.860 113.677 1.00 97.84 ? 140 VAL A O   1 
ATOM   743  C  CB  . VAL A 1 152 ? 101.132 113.641 110.506 1.00 97.84 ? 140 VAL A CB  1 
ATOM   744  C  CG1 . VAL A 1 152 ? 99.843  114.069 111.187 1.00 97.84 ? 140 VAL A CG1 1 
ATOM   745  C  CG2 . VAL A 1 152 ? 101.529 114.669 109.461 1.00 97.84 ? 140 VAL A CG2 1 
ATOM   746  N  N   . ILE A 1 153 ? 102.247 111.196 112.451 1.00 95.74 ? 141 ILE A N   1 
ATOM   747  C  CA  . ILE A 1 153 ? 102.020 110.205 113.498 1.00 95.74 ? 141 ILE A CA  1 
ATOM   748  C  C   . ILE A 1 153 ? 102.850 110.570 114.712 1.00 95.74 ? 141 ILE A C   1 
ATOM   749  O  O   . ILE A 1 153 ? 102.391 110.440 115.836 1.00 95.74 ? 141 ILE A O   1 
ATOM   750  C  CB  . ILE A 1 153 ? 102.411 108.790 113.032 1.00 95.74 ? 141 ILE A CB  1 
ATOM   751  C  CG1 . ILE A 1 153 ? 102.082 108.597 111.559 1.00 95.74 ? 141 ILE A CG1 1 
ATOM   752  C  CG2 . ILE A 1 153 ? 101.735 107.727 113.884 1.00 95.74 ? 141 ILE A CG2 1 
ATOM   753  C  CD1 . ILE A 1 153 ? 102.924 107.530 110.904 1.00 95.74 ? 141 ILE A CD1 1 
ATOM   754  N  N   . LEU A 1 154 ? 104.077 111.014 114.496 1.00 97.83 ? 142 LEU A N   1 
ATOM   755  C  CA  . LEU A 1 154 ? 104.934 111.461 115.589 1.00 97.83 ? 142 LEU A CA  1 
ATOM   756  C  C   . LEU A 1 154 ? 104.382 112.690 116.297 1.00 97.83 ? 142 LEU A C   1 
ATOM   757  O  O   . LEU A 1 154 ? 104.508 112.803 117.502 1.00 97.83 ? 142 LEU A O   1 
ATOM   758  C  CB  . LEU A 1 154 ? 106.343 111.718 115.077 1.00 97.83 ? 142 LEU A CB  1 
ATOM   759  C  CG  . LEU A 1 154 ? 106.999 110.518 114.406 1.00 97.83 ? 142 LEU A CG  1 
ATOM   760  C  CD1 . LEU A 1 154 ? 108.303 110.916 113.737 1.00 97.83 ? 142 LEU A CD1 1 
ATOM   761  C  CD2 . LEU A 1 154 ? 107.221 109.432 115.441 1.00 97.83 ? 142 LEU A CD2 1 
ATOM   762  N  N   . ALA A 1 155 ? 103.798 113.625 115.557 1.00 98.50 ? 143 ALA A N   1 
ATOM   763  C  CA  . ALA A 1 155 ? 103.185 114.803 116.163 1.00 98.50 ? 143 ALA A CA  1 
ATOM   764  C  C   . ALA A 1 155 ? 102.028 114.419 117.055 1.00 98.50 ? 143 ALA A C   1 
ATOM   765  O  O   . ALA A 1 155 ? 101.731 115.128 118.006 1.00 98.50 ? 143 ALA A O   1 
ATOM   766  C  CB  . ALA A 1 155 ? 102.717 115.758 115.096 1.00 98.50 ? 143 ALA A CB  1 
ATOM   767  N  N   . TRP A 1 156 ? 101.352 113.316 116.750 1.00 98.00 ? 144 TRP A N   1 
ATOM   768  C  CA  . TRP A 1 156 ? 100.281 112.831 117.617 1.00 98.00 ? 144 TRP A CA  1 
ATOM   769  C  C   . TRP A 1 156 ? 100.869 112.214 118.863 1.00 98.00 ? 144 TRP A C   1 
ATOM   770  O  O   . TRP A 1 156 ? 100.346 112.398 119.947 1.00 98.00 ? 144 TRP A O   1 
ATOM   771  C  CB  . TRP A 1 156 ? 99.434  111.790 116.899 1.00 98.00 ? 144 TRP A CB  1 
ATOM   772  C  CG  . TRP A 1 156 ? 98.640  112.298 115.751 1.00 98.00 ? 144 TRP A CG  1 
ATOM   773  C  CD1 . TRP A 1 156 ? 98.072  113.527 115.625 1.00 98.00 ? 144 TRP A CD1 1 
ATOM   774  C  CD2 . TRP A 1 156 ? 98.295  111.573 114.567 1.00 98.00 ? 144 TRP A CD2 1 
ATOM   775  N  NE1 . TRP A 1 156 ? 97.407  113.621 114.430 1.00 98.00 ? 144 TRP A NE1 1 
ATOM   776  C  CE2 . TRP A 1 156 ? 97.527  112.432 113.762 1.00 98.00 ? 144 TRP A CE2 1 
ATOM   777  C  CE3 . TRP A 1 156 ? 98.564  110.281 114.109 1.00 98.00 ? 144 TRP A CE3 1 
ATOM   778  C  CZ2 . TRP A 1 156 ? 97.027  112.042 112.524 1.00 98.00 ? 144 TRP A CZ2 1 
ATOM   779  C  CZ3 . TRP A 1 156 ? 98.070  109.898 112.883 1.00 98.00 ? 144 TRP A CZ3 1 
ATOM   780  C  CH2 . TRP A 1 156 ? 97.310  110.774 112.104 1.00 98.00 ? 144 TRP A CH2 1 
ATOM   781  N  N   . ALA A 1 157 ? 101.949 111.464 118.713 1.00 97.45 ? 145 ALA A N   1 
ATOM   782  C  CA  . ALA A 1 157 ? 102.619 110.852 119.850 1.00 97.45 ? 145 ALA A CA  1 
ATOM   783  C  C   . ALA A 1 157 ? 103.182 111.900 120.779 1.00 97.45 ? 145 ALA A C   1 
ATOM   784  O  O   . ALA A 1 157 ? 103.117 111.744 121.988 1.00 97.45 ? 145 ALA A O   1 
ATOM   785  C  CB  . ALA A 1 157 ? 103.716 109.931 119.361 1.00 97.45 ? 145 ALA A CB  1 
ATOM   786  N  N   . THR A 1 158 ? 103.754 112.963 120.226 1.00 98.50 ? 146 THR A N   1 
ATOM   787  C  CA  . THR A 1 158 ? 104.277 114.059 121.032 1.00 98.50 ? 146 THR A CA  1 
ATOM   788  C  C   . THR A 1 158 ? 103.150 114.728 121.789 1.00 98.50 ? 146 THR A C   1 
ATOM   789  O  O   . THR A 1 158 ? 103.310 115.095 122.944 1.00 98.50 ? 146 THR A O   1 
ATOM   790  C  CB  . THR A 1 158 ? 104.999 115.097 120.166 1.00 98.50 ? 146 THR A CB  1 
ATOM   791  O  OG1 . THR A 1 158 ? 105.803 114.428 119.190 1.00 98.50 ? 146 THR A OG1 1 
ATOM   792  C  CG2 . THR A 1 158 ? 105.892 115.974 121.010 1.00 98.50 ? 146 THR A CG2 1 
ATOM   793  N  N   . TYR A 1 159 ? 102.005 114.893 121.144 1.00 98.43 ? 147 TYR A N   1 
ATOM   794  C  CA  . TYR A 1 159 ? 100.859 115.482 121.810 1.00 98.43 ? 147 TYR A CA  1 
ATOM   795  C  C   . TYR A 1 159 ? 100.393 114.624 122.962 1.00 98.43 ? 147 TYR A C   1 
ATOM   796  O  O   . TYR A 1 159 ? 100.121 115.138 124.037 1.00 98.43 ? 147 TYR A O   1 
ATOM   797  C  CB  . TYR A 1 159 ? 99.728  115.646 120.811 1.00 98.43 ? 147 TYR A CB  1 
ATOM   798  C  CG  . TYR A 1 159 ? 98.590  116.486 121.309 1.00 98.43 ? 147 TYR A CG  1 
ATOM   799  C  CD1 . TYR A 1 159 ? 98.690  117.866 121.345 1.00 98.43 ? 147 TYR A CD1 1 
ATOM   800  C  CD2 . TYR A 1 159 ? 97.414  115.902 121.738 1.00 98.43 ? 147 TYR A CD2 1 
ATOM   801  C  CE1 . TYR A 1 159 ? 97.648  118.642 121.802 1.00 98.43 ? 147 TYR A CE1 1 
ATOM   802  C  CE2 . TYR A 1 159 ? 96.370  116.668 122.195 1.00 98.43 ? 147 TYR A CE2 1 
ATOM   803  C  CZ  . TYR A 1 159 ? 96.491  118.037 122.224 1.00 98.43 ? 147 TYR A CZ  1 
ATOM   804  O  OH  . TYR A 1 159 ? 95.448  118.806 122.679 1.00 98.43 ? 147 TYR A OH  1 
ATOM   805  N  N   . TYR A 1 160 ? 100.320 113.316 122.757 1.00 98.17 ? 148 TYR A N   1 
ATOM   806  C  CA  . TYR A 1 160 ? 99.933  112.392 123.817 1.00 98.17 ? 148 TYR A CA  1 
ATOM   807  C  C   . TYR A 1 160 ? 100.954 112.403 124.935 1.00 98.17 ? 148 TYR A C   1 
ATOM   808  O  O   . TYR A 1 160 ? 100.592 112.269 126.088 1.00 98.17 ? 148 TYR A O   1 
ATOM   809  C  CB  . TYR A 1 160 ? 99.784  110.988 123.260 1.00 98.17 ? 148 TYR A CB  1 
ATOM   810  C  CG  . TYR A 1 160 ? 98.420  110.605 122.734 1.00 98.17 ? 148 TYR A CG  1 
ATOM   811  C  CD1 . TYR A 1 160 ? 98.016  110.958 121.457 1.00 98.17 ? 148 TYR A CD1 1 
ATOM   812  C  CD2 . TYR A 1 160 ? 97.554  109.848 123.502 1.00 98.17 ? 148 TYR A CD2 1 
ATOM   813  C  CE1 . TYR A 1 160 ? 96.777  110.590 120.976 1.00 98.17 ? 148 TYR A CE1 1 
ATOM   814  C  CE2 . TYR A 1 160 ? 96.315  109.475 123.030 1.00 98.17 ? 148 TYR A CE2 1 
ATOM   815  C  CZ  . TYR A 1 160 ? 95.932  109.849 121.769 1.00 98.17 ? 148 TYR A CZ  1 
ATOM   816  O  OH  . TYR A 1 160 ? 94.696  109.477 121.303 1.00 98.17 ? 148 TYR A OH  1 
ATOM   817  N  N   . LEU A 1 161 ? 102.235 112.507 124.600 1.00 97.95 ? 149 LEU A N   1 
ATOM   818  C  CA  . LEU A 1 161 ? 103.290 112.593 125.607 1.00 97.95 ? 149 LEU A CA  1 
ATOM   819  C  C   . LEU A 1 161 ? 103.161 113.847 126.467 1.00 97.95 ? 149 LEU A C   1 
ATOM   820  O  O   . LEU A 1 161 ? 103.358 113.794 127.671 1.00 97.95 ? 149 LEU A O   1 
ATOM   821  C  CB  . LEU A 1 161 ? 104.654 112.571 124.920 1.00 97.95 ? 149 LEU A CB  1 
ATOM   822  C  CG  . LEU A 1 161 ? 105.937 112.720 125.730 1.00 97.95 ? 149 LEU A CG  1 
ATOM   823  C  CD1 . LEU A 1 161 ? 106.088 111.550 126.679 1.00 97.95 ? 149 LEU A CD1 1 
ATOM   824  C  CD2 . LEU A 1 161 ? 107.123 112.789 124.785 1.00 97.95 ? 149 LEU A CD2 1 
ATOM   825  N  N   . PHE A 1 162 ? 102.849 114.985 125.866 1.00 98.26 ? 150 PHE A N   1 
ATOM   826  C  CA  . PHE A 1 162 ? 102.622 116.186 126.656 1.00 98.26 ? 150 PHE A CA  1 
ATOM   827  C  C   . PHE A 1 162 ? 101.399 115.999 127.534 1.00 98.26 ? 150 PHE A C   1 
ATOM   828  O  O   . PHE A 1 162 ? 101.391 116.415 128.687 1.00 98.26 ? 150 PHE A O   1 
ATOM   829  C  CB  . PHE A 1 162 ? 102.451 117.402 125.757 1.00 98.26 ? 150 PHE A CB  1 
ATOM   830  C  CG  . PHE A 1 162 ? 103.695 117.786 125.015 1.00 98.26 ? 150 PHE A CG  1 
ATOM   831  C  CD1 . PHE A 1 162 ? 104.944 117.522 125.547 1.00 98.26 ? 150 PHE A CD1 1 
ATOM   832  C  CD2 . PHE A 1 162 ? 103.614 118.427 123.793 1.00 98.26 ? 150 PHE A CD2 1 
ATOM   833  C  CE1 . PHE A 1 162 ? 106.091 117.876 124.868 1.00 98.26 ? 150 PHE A CE1 1 
ATOM   834  C  CE2 . PHE A 1 162 ? 104.758 118.788 123.109 1.00 98.26 ? 150 PHE A CE2 1 
ATOM   835  C  CZ  . PHE A 1 162 ? 105.998 118.512 123.648 1.00 98.26 ? 150 PHE A CZ  1 
ATOM   836  N  N   . GLN A 1 163 ? 100.356 115.387 126.990 1.00 97.54 ? 151 GLN A N   1 
ATOM   837  C  CA  . GLN A 1 163 ? 99.142  115.118 127.753 1.00 97.54 ? 151 GLN A CA  1 
ATOM   838  C  C   . GLN A 1 163 ? 99.411  114.144 128.875 1.00 97.54 ? 151 GLN A C   1 
ATOM   839  O  O   . GLN A 1 163 ? 98.777  114.205 129.918 1.00 97.54 ? 151 GLN A O   1 
ATOM   840  C  CB  . GLN A 1 163 ? 98.040  114.599 126.838 1.00 97.54 ? 151 GLN A CB  1 
ATOM   841  C  CG  . GLN A 1 163 ? 97.540  115.601 125.812 1.00 97.54 ? 151 GLN A CG  1 
ATOM   842  C  CD  . GLN A 1 163 ? 96.552  116.596 126.381 1.00 97.54 ? 151 GLN A CD  1 
ATOM   843  O  OE1 . GLN A 1 163 ? 95.881  116.326 127.374 1.00 97.54 ? 151 GLN A OE1 1 
ATOM   844  N  NE2 . GLN A 1 163 ? 96.447  117.751 125.741 1.00 97.54 ? 151 GLN A NE2 1 
ATOM   845  N  N   . SER A 1 164 ? 100.336 113.225 128.663 1.00 97.64 ? 152 SER A N   1 
ATOM   846  C  CA  . SER A 1 164 ? 100.652 112.206 129.662 1.00 97.64 ? 152 SER A CA  1 
ATOM   847  C  C   . SER A 1 164 ? 101.187 112.714 130.986 1.00 97.64 ? 152 SER A C   1 
ATOM   848  O  O   . SER A 1 164 ? 100.921 112.116 132.014 1.00 97.64 ? 152 SER A O   1 
ATOM   849  C  CB  . SER A 1 164 ? 101.624 111.189 129.095 1.00 97.64 ? 152 SER A CB  1 
ATOM   850  O  OG  . SER A 1 164 ? 102.937 111.691 129.087 1.00 97.64 ? 152 SER A OG  1 
ATOM   851  N  N   . PHE A 1 165 ? 101.891 113.842 130.980 1.00 96.62 ? 153 PHE A N   1 
ATOM   852  C  CA  . PHE A 1 165 ? 102.512 114.378 132.196 1.00 96.62 ? 153 PHE A CA  1 
ATOM   853  C  C   . PHE A 1 165 ? 101.558 114.701 133.339 1.00 96.62 ? 153 PHE A C   1 
ATOM   854  O  O   . PHE A 1 165 ? 101.994 114.902 134.468 1.00 96.62 ? 153 PHE A O   1 
ATOM   855  C  CB  . PHE A 1 165 ? 103.338 115.618 131.867 1.00 96.62 ? 153 PHE A CB  1 
ATOM   856  C  CG  . PHE A 1 165 ? 104.429 115.376 130.865 1.00 96.62 ? 153 PHE A CG  1 
ATOM   857  C  CD1 . PHE A 1 165 ? 105.244 114.266 130.963 1.00 96.62 ? 153 PHE A CD1 1 
ATOM   858  C  CD2 . PHE A 1 165 ? 104.655 116.275 129.841 1.00 96.62 ? 153 PHE A CD2 1 
ATOM   859  C  CE1 . PHE A 1 165 ? 106.251 114.043 130.047 1.00 96.62 ? 153 PHE A CE1 1 
ATOM   860  C  CE2 . PHE A 1 165 ? 105.663 116.061 128.922 1.00 96.62 ? 153 PHE A CE2 1 
ATOM   861  C  CZ  . PHE A 1 165 ? 106.462 114.942 129.024 1.00 96.62 ? 153 PHE A CZ  1 
ATOM   862  N  N   . GLN A 1 166 ? 100.263 114.749 133.063 1.00 94.49 ? 154 GLN A N   1 
ATOM   863  C  CA  . GLN A 1 166 ? 99.278  115.020 134.102 1.00 94.49 ? 154 GLN A CA  1 
ATOM   864  C  C   . GLN A 1 166 ? 99.166  113.838 135.044 1.00 94.49 ? 154 GLN A C   1 
ATOM   865  O  O   . GLN A 1 166 ? 99.480  112.710 134.675 1.00 94.49 ? 154 GLN A O   1 
ATOM   866  C  CB  . GLN A 1 166 ? 97.913  115.300 133.484 1.00 94.49 ? 154 GLN A CB  1 
ATOM   867  C  CG  . GLN A 1 166 ? 97.943  116.275 132.323 1.00 94.49 ? 154 GLN A CG  1 
ATOM   868  C  CD  . GLN A 1 166 ? 96.678  116.216 131.494 1.00 94.49 ? 154 GLN A CD  1 
ATOM   869  O  OE1 . GLN A 1 166 ? 95.672  115.651 131.920 1.00 94.49 ? 154 GLN A OE1 1 
ATOM   870  N  NE2 . GLN A 1 166 ? 96.723  116.798 130.303 1.00 94.49 ? 154 GLN A NE2 1 
ATOM   871  N  N   . LYS A 1 167 ? 98.718  114.089 136.267 1.00 91.81 ? 155 LYS A N   1 
ATOM   872  C  CA  . LYS A 1 167 ? 98.567  113.018 137.245 1.00 91.81 ? 155 LYS A CA  1 
ATOM   873  C  C   . LYS A 1 167 ? 97.551  112.002 136.772 1.00 91.81 ? 155 LYS A C   1 
ATOM   874  O  O   . LYS A 1 167 ? 97.750  110.800 136.926 1.00 91.81 ? 155 LYS A O   1 
ATOM   875  C  CB  . LYS A 1 167 ? 98.133  113.600 138.586 1.00 91.81 ? 155 LYS A CB  1 
ATOM   876  C  CG  . LYS A 1 167 ? 99.069  114.678 139.105 1.00 91.81 ? 155 LYS A CG  1 
ATOM   877  C  CD  . LYS A 1 167 ? 100.465 114.122 139.334 1.00 91.81 ? 155 LYS A CD  1 
ATOM   878  C  CE  . LYS A 1 167 ? 101.515 115.214 139.230 1.00 91.81 ? 155 LYS A CE  1 
ATOM   879  N  NZ  . LYS A 1 167 ? 101.551 115.801 137.861 1.00 91.81 ? 155 LYS A NZ  1 
ATOM   880  N  N   . GLU A 1 168 ? 96.460  112.479 136.192 1.00 93.25 ? 156 GLU A N   1 
ATOM   881  C  CA  . GLU A 1 168 ? 95.451  111.581 135.662 1.00 93.25 ? 156 GLU A CA  1 
ATOM   882  C  C   . GLU A 1 168 ? 95.483  111.688 134.155 1.00 93.25 ? 156 GLU A C   1 
ATOM   883  O  O   . GLU A 1 168 ? 95.396  112.782 133.606 1.00 93.25 ? 156 GLU A O   1 
ATOM   884  C  CB  . GLU A 1 168 ? 94.074  111.979 136.186 1.00 93.25 ? 156 GLU A CB  1 
ATOM   885  C  CG  . GLU A 1 168 ? 92.904  111.353 135.448 1.00 93.25 ? 156 GLU A CG  1 
ATOM   886  C  CD  . GLU A 1 168 ? 91.581  111.975 135.840 1.00 93.25 ? 156 GLU A CD  1 
ATOM   887  O  OE1 . GLU A 1 168 ? 90.797  112.327 134.934 1.00 93.25 ? 156 GLU A OE1 1 
ATOM   888  O  OE2 . GLU A 1 168 ? 91.331  112.126 137.053 1.00 93.25 ? 156 GLU A OE2 1 
ATOM   889  N  N   . LEU A 1 169 ? 95.619  110.555 133.479 1.00 95.75 ? 157 LEU A N   1 
ATOM   890  C  CA  . LEU A 1 169 ? 95.642  110.562 132.029 1.00 95.75 ? 157 LEU A CA  1 
ATOM   891  C  C   . LEU A 1 169 ? 94.294  111.041 131.532 1.00 95.75 ? 157 LEU A C   1 
ATOM   892  O  O   . LEU A 1 169 ? 93.258  110.615 132.033 1.00 95.75 ? 157 LEU A O   1 
ATOM   893  C  CB  . LEU A 1 169 ? 95.951  109.165 131.504 1.00 95.75 ? 157 LEU A CB  1 
ATOM   894  C  CG  . LEU A 1 169 ? 97.258  108.550 131.997 1.00 95.75 ? 157 LEU A CG  1 
ATOM   895  C  CD1 . LEU A 1 169 ? 97.364  107.110 131.535 1.00 95.75 ? 157 LEU A CD1 1 
ATOM   896  C  CD2 . LEU A 1 169 ? 98.452  109.361 131.521 1.00 95.75 ? 157 LEU A CD2 1 
ATOM   897  N  N   . PRO A 1 170 ? 94.297  111.935 130.540 1.00 95.83 ? 158 PRO A N   1 
ATOM   898  C  CA  . PRO A 1 170 ? 93.035  112.492 130.044 1.00 95.83 ? 158 PRO A CA  1 
ATOM   899  C  C   . PRO A 1 170 ? 92.123  111.435 129.435 1.00 95.83 ? 158 PRO A C   1 
ATOM   900  O  O   . PRO A 1 170 ? 90.917  111.487 129.651 1.00 95.83 ? 158 PRO A O   1 
ATOM   901  C  CB  . PRO A 1 170 ? 93.483  113.502 128.988 1.00 95.83 ? 158 PRO A CB  1 
ATOM   902  C  CG  . PRO A 1 170 ? 94.929  113.243 128.741 1.00 95.83 ? 158 PRO A CG  1 
ATOM   903  C  CD  . PRO A 1 170 ? 95.473  112.614 129.978 1.00 95.83 ? 158 PRO A CD  1 
ATOM   904  N  N   . TRP A 1 171 ? 92.675  110.463 128.722 1.00 95.20 ? 159 TRP A N   1 
ATOM   905  C  CA  . TRP A 1 171 ? 91.863  109.443 128.073 1.00 95.20 ? 159 TRP A CA  1 
ATOM   906  C  C   . TRP A 1 171 ? 91.238  108.451 129.040 1.00 95.20 ? 159 TRP A C   1 
ATOM   907  O  O   . TRP A 1 171 ? 90.306  107.750 128.684 1.00 95.20 ? 159 TRP A O   1 
ATOM   908  C  CB  . TRP A 1 171 ? 92.681  108.712 127.015 1.00 95.20 ? 159 TRP A CB  1 
ATOM   909  C  CG  . TRP A 1 171 ? 94.015  108.216 127.460 1.00 95.20 ? 159 TRP A CG  1 
ATOM   910  C  CD1 . TRP A 1 171 ? 94.294  107.004 128.011 1.00 95.20 ? 159 TRP A CD1 1 
ATOM   911  C  CD2 . TRP A 1 171 ? 95.264  108.907 127.356 1.00 95.20 ? 159 TRP A CD2 1 
ATOM   912  N  NE1 . TRP A 1 171 ? 95.637  106.901 128.273 1.00 95.20 ? 159 TRP A NE1 1 
ATOM   913  C  CE2 . TRP A 1 171 ? 96.255  108.058 127.878 1.00 95.20 ? 159 TRP A CE2 1 
ATOM   914  C  CE3 . TRP A 1 171 ? 95.639  110.165 126.879 1.00 95.20 ? 159 TRP A CE3 1 
ATOM   915  C  CZ2 . TRP A 1 171 ? 97.595  108.424 127.935 1.00 95.20 ? 159 TRP A CZ2 1 
ATOM   916  C  CZ3 . TRP A 1 171 ? 96.968  110.528 126.941 1.00 95.20 ? 159 TRP A CZ3 1 
ATOM   917  C  CH2 . TRP A 1 171 ? 97.930  109.662 127.464 1.00 95.20 ? 159 TRP A CH2 1 
ATOM   918  N  N   . ALA A 1 172 ? 91.758  108.373 130.254 1.00 93.12 ? 160 ALA A N   1 
ATOM   919  C  CA  . ALA A 1 172 ? 91.226  107.456 131.259 1.00 93.12 ? 160 ALA A CA  1 
ATOM   920  C  C   . ALA A 1 172 ? 89.808  107.744 131.708 1.00 93.12 ? 160 ALA A C   1 
ATOM   921  O  O   . ALA A 1 172 ? 89.024  106.822 131.911 1.00 93.12 ? 160 ALA A O   1 
ATOM   922  C  CB  . ALA A 1 172 ? 92.143  107.421 132.465 1.00 93.12 ? 160 ALA A CB  1 
ATOM   923  N  N   . HIS A 1 173 ? 89.461  109.013 131.875 1.00 92.31 ? 161 HIS A N   1 
ATOM   924  C  CA  . HIS A 1 173 ? 88.133  109.341 132.395 1.00 92.31 ? 161 HIS A CA  1 
ATOM   925  C  C   . HIS A 1 173 ? 87.233  110.115 131.457 1.00 92.31 ? 161 HIS A C   1 
ATOM   926  O  O   . HIS A 1 173 ? 87.652  110.515 130.374 1.00 92.31 ? 161 HIS A O   1 
ATOM   927  C  CB  . HIS A 1 173 ? 88.233  110.014 133.762 1.00 92.31 ? 161 HIS A CB  1 
ATOM   928  C  CG  . HIS A 1 173 ? 88.722  109.096 134.837 1.00 92.31 ? 161 HIS A CG  1 
ATOM   929  N  ND1 . HIS A 1 173 ? 87.922  108.133 135.410 1.00 92.31 ? 161 HIS A ND1 1 
ATOM   930  C  CD2 . HIS A 1 173 ? 89.935  108.977 135.426 1.00 92.31 ? 161 HIS A CD2 1 
ATOM   931  C  CE1 . HIS A 1 173 ? 88.617  107.468 136.315 1.00 92.31 ? 161 HIS A CE1 1 
ATOM   932  N  NE2 . HIS A 1 173 ? 89.841  107.961 136.345 1.00 92.31 ? 161 HIS A NE2 1 
ATOM   933  N  N   . CYS A 1 174 ? 85.986  110.314 131.859 1.00 91.54 ? 162 CYS A N   1 
ATOM   934  C  CA  . CYS A 1 174 ? 85.031  110.947 130.962 1.00 91.54 ? 162 CYS A CA  1 
ATOM   935  C  C   . CYS A 1 174 ? 84.461  112.327 131.353 1.00 91.54 ? 162 CYS A C   1 
ATOM   936  O  O   . CYS A 1 174 ? 83.701  112.923 130.601 1.00 91.54 ? 162 CYS A O   1 
ATOM   937  C  CB  . CYS A 1 174 ? 83.913  109.938 130.705 1.00 91.54 ? 162 CYS A CB  1 
ATOM   938  S  SG  . CYS A 1 174 ? 82.739  110.386 129.427 1.00 91.54 ? 162 CYS A SG  1 
ATOM   939  N  N   . ASN A 1 175 ? 84.817  112.863 132.508 1.00 90.87 ? 163 ASN A N   1 
ATOM   940  C  CA  . ASN A 1 175 ? 84.331  114.202 132.841 1.00 90.87 ? 163 ASN A CA  1 
ATOM   941  C  C   . ASN A 1 175 ? 85.237  115.305 132.323 1.00 90.87 ? 163 ASN A C   1 
ATOM   942  O  O   . ASN A 1 175 ? 85.941  115.943 133.101 1.00 90.87 ? 163 ASN A O   1 
ATOM   943  C  CB  . ASN A 1 175 ? 84.120  114.351 134.346 1.00 90.87 ? 163 ASN A CB  1 
ATOM   944  C  CG  . ASN A 1 175 ? 82.878  113.632 134.831 1.00 90.87 ? 163 ASN A CG  1 
ATOM   945  O  OD1 . ASN A 1 175 ? 82.082  113.138 134.032 1.00 90.87 ? 163 ASN A OD1 1 
ATOM   946  N  ND2 . ASN A 1 175 ? 82.701  113.576 136.145 1.00 90.87 ? 163 ASN A ND2 1 
ATOM   947  N  N   . HIS A 1 176 ? 85.218  115.540 131.017 1.00 94.79 ? 164 HIS A N   1 
ATOM   948  C  CA  . HIS A 1 176 ? 86.081  116.556 130.427 1.00 94.79 ? 164 HIS A CA  1 
ATOM   949  C  C   . HIS A 1 176 ? 85.322  117.393 129.412 1.00 94.79 ? 164 HIS A C   1 
ATOM   950  O  O   . HIS A 1 176 ? 84.194  117.066 129.057 1.00 94.79 ? 164 HIS A O   1 
ATOM   951  C  CB  . HIS A 1 176 ? 87.293  115.920 129.754 1.00 94.79 ? 164 HIS A CB  1 
ATOM   952  C  CG  . HIS A 1 176 ? 88.112  115.050 130.655 1.00 94.79 ? 164 HIS A CG  1 
ATOM   953  N  ND1 . HIS A 1 176 ? 89.079  115.551 131.497 1.00 94.79 ? 164 HIS A ND1 1 
ATOM   954  C  CD2 . HIS A 1 176 ? 88.125  113.707 130.825 1.00 94.79 ? 164 HIS A CD2 1 
ATOM   955  C  CE1 . HIS A 1 176 ? 89.643  114.556 132.158 1.00 94.79 ? 164 HIS A CE1 1 
ATOM   956  N  NE2 . HIS A 1 176 ? 89.082  113.427 131.769 1.00 94.79 ? 164 HIS A NE2 1 
ATOM   957  N  N   . SER A 1 177 ? 85.935  118.469 128.940 1.00 95.56 ? 165 SER A N   1 
ATOM   958  C  CA  . SER A 1 177 ? 85.274  119.357 127.989 1.00 95.56 ? 165 SER A CA  1 
ATOM   959  C  C   . SER A 1 177 ? 84.998  118.701 126.648 1.00 95.56 ? 165 SER A C   1 
ATOM   960  O  O   . SER A 1 177 ? 83.921  118.872 126.084 1.00 95.56 ? 165 SER A O   1 
ATOM   961  C  CB  . SER A 1 177 ? 86.133  120.598 127.767 1.00 95.56 ? 165 SER A CB  1 
ATOM   962  O  OG  . SER A 1 177 ? 86.490  121.199 128.999 1.00 95.56 ? 165 SER A OG  1 
ATOM   963  N  N   . TRP A 1 178 ? 85.965  117.954 126.131 1.00 95.13 ? 166 TRP A N   1 
ATOM   964  C  CA  . TRP A 1 178 ? 85.782  117.255 124.864 1.00 95.13 ? 166 TRP A CA  1 
ATOM   965  C  C   . TRP A 1 178 ? 84.713  116.198 124.945 1.00 95.13 ? 166 TRP A C   1 
ATOM   966  O  O   . TRP A 1 178 ? 84.000  115.962 123.985 1.00 95.13 ? 166 TRP A O   1 
ATOM   967  C  CB  . TRP A 1 178 ? 87.091  116.664 124.337 1.00 95.13 ? 166 TRP A CB  1 
ATOM   968  C  CG  . TRP A 1 178 ? 87.766  115.677 125.229 1.00 95.13 ? 166 TRP A CG  1 
ATOM   969  C  CD1 . TRP A 1 178 ? 87.568  114.330 125.261 1.00 95.13 ? 166 TRP A CD1 1 
ATOM   970  C  CD2 . TRP A 1 178 ? 88.781  115.955 126.196 1.00 95.13 ? 166 TRP A CD2 1 
ATOM   971  N  NE1 . TRP A 1 178 ? 88.382  113.754 126.202 1.00 95.13 ? 166 TRP A NE1 1 
ATOM   972  C  CE2 . TRP A 1 178 ? 89.140  114.732 126.788 1.00 95.13 ? 166 TRP A CE2 1 
ATOM   973  C  CE3 . TRP A 1 178 ? 89.416  117.124 126.625 1.00 95.13 ? 166 TRP A CE3 1 
ATOM   974  C  CZ2 . TRP A 1 178 ? 90.105  114.643 127.784 1.00 95.13 ? 166 TRP A CZ2 1 
ATOM   975  C  CZ3 . TRP A 1 178 ? 90.372  117.033 127.612 1.00 95.13 ? 166 TRP A CZ3 1 
ATOM   976  C  CH2 . TRP A 1 178 ? 90.708  115.803 128.180 1.00 95.13 ? 166 TRP A CH2 1 
ATOM   977  N  N   . ASN A 1 179 ? 84.599  115.536 126.084 1.00 95.91 ? 167 ASN A N   1 
ATOM   978  C  CA  . ASN A 1 179 ? 83.669  114.429 126.175 1.00 95.91 ? 167 ASN A CA  1 
ATOM   979  C  C   . ASN A 1 179 ? 82.225  114.783 125.906 1.00 95.91 ? 167 ASN A C   1 
ATOM   980  O  O   . ASN A 1 179 ? 81.710  115.770 126.424 1.00 95.91 ? 167 ASN A O   1 
ATOM   981  C  CB  . ASN A 1 179 ? 83.829  113.730 127.519 1.00 95.91 ? 167 ASN A CB  1 
ATOM   982  C  CG  . ASN A 1 179 ? 85.134  112.972 127.621 1.00 95.91 ? 167 ASN A CG  1 
ATOM   983  O  OD1 . ASN A 1 179 ? 85.937  113.216 128.513 1.00 95.91 ? 167 ASN A OD1 1 
ATOM   984  N  ND2 . ASN A 1 179 ? 85.358  112.055 126.691 1.00 95.91 ? 167 ASN A ND2 1 
ATOM   985  N  N   . THR A 1 180 ? 81.568  113.970 125.090 1.00 93.30 ? 168 THR A N   1 
ATOM   986  C  CA  . THR A 1 180 ? 80.167  114.189 124.750 1.00 93.30 ? 168 THR A CA  1 
ATOM   987  C  C   . THR A 1 180 ? 79.249  113.654 125.838 1.00 93.30 ? 168 THR A C   1 
ATOM   988  O  O   . THR A 1 180 ? 79.699  112.952 126.740 1.00 93.30 ? 168 THR A O   1 
ATOM   989  C  CB  . THR A 1 180 ? 79.830  113.490 123.422 1.00 93.30 ? 168 THR A CB  1 
ATOM   990  O  OG1 . THR A 1 180 ? 79.825  112.072 123.615 1.00 93.30 ? 168 THR A OG1 1 
ATOM   991  C  CG2 . THR A 1 180 ? 80.841  113.853 122.357 1.00 93.30 ? 168 THR A CG2 1 
ATOM   992  N  N   . PRO A 1 181 ? 77.927  113.986 125.786 1.00 89.35 ? 169 PRO A N   1 
ATOM   993  C  CA  . PRO A 1 181 ? 77.096  113.354 126.823 1.00 89.35 ? 169 PRO A CA  1 
ATOM   994  C  C   . PRO A 1 181 ? 77.017  111.851 126.618 1.00 89.35 ? 169 PRO A C   1 
ATOM   995  O  O   . PRO A 1 181 ? 76.728  111.126 127.569 1.00 89.35 ? 169 PRO A O   1 
ATOM   996  C  CB  . PRO A 1 181 ? 75.717  113.987 126.610 1.00 89.35 ? 169 PRO A CB  1 
ATOM   997  C  CG  . PRO A 1 181 ? 75.736  114.526 125.224 1.00 89.35 ? 169 PRO A CG  1 
ATOM   998  C  CD  . PRO A 1 181 ? 77.139  115.007 125.054 1.00 89.35 ? 169 PRO A CD  1 
ATOM   999  N  N   . HIS A 1 182 ? 77.256  111.387 125.398 1.00 88.40 ? 170 HIS A N   1 
ATOM   1000 C  CA  . HIS A 1 182 ? 77.249  109.955 125.104 1.00 88.40 ? 170 HIS A CA  1 
ATOM   1001 C  C   . HIS A 1 182 ? 78.345  109.181 125.813 1.00 88.40 ? 170 HIS A C   1 
ATOM   1002 O  O   . HIS A 1 182 ? 78.129  108.046 126.221 1.00 88.40 ? 170 HIS A O   1 
ATOM   1003 C  CB  . HIS A 1 182 ? 77.313  109.712 123.601 1.00 88.40 ? 170 HIS A CB  1 
ATOM   1004 C  CG  . HIS A 1 182 ? 76.118  110.223 122.862 1.00 88.40 ? 170 HIS A CG  1 
ATOM   1005 N  ND1 . HIS A 1 182 ? 74.916  109.551 122.840 1.00 88.40 ? 170 HIS A ND1 1 
ATOM   1006 C  CD2 . HIS A 1 182 ? 75.938  111.343 122.124 1.00 88.40 ? 170 HIS A CD2 1 
ATOM   1007 C  CE1 . HIS A 1 182 ? 74.046  110.233 122.118 1.00 88.40 ? 170 HIS A CE1 1 
ATOM   1008 N  NE2 . HIS A 1 182 ? 74.641  111.325 121.672 1.00 88.40 ? 170 HIS A NE2 1 
ATOM   1009 N  N   . CYS A 1 183 ? 79.522  109.777 125.967 1.00 90.60 ? 171 CYS A N   1 
ATOM   1010 C  CA  . CYS A 1 183 ? 80.637  109.034 126.542 1.00 90.60 ? 171 CYS A CA  1 
ATOM   1011 C  C   . CYS A 1 183 ? 80.320  108.483 127.912 1.00 90.60 ? 171 CYS A C   1 
ATOM   1012 O  O   . CYS A 1 183 ? 79.750  109.174 128.753 1.00 90.60 ? 171 CYS A O   1 
ATOM   1013 C  CB  . CYS A 1 183 ? 81.904  109.898 126.601 1.00 90.60 ? 171 CYS A CB  1 
ATOM   1014 S  SG  . CYS A 1 183 ? 83.183  109.333 127.753 1.00 90.60 ? 171 CYS A SG  1 
ATOM   1015 N  N   . MET A 1 184 ? 80.679  107.223 128.131 1.00 87.51 ? 172 MET A N   1 
ATOM   1016 C  CA  . MET A 1 184 ? 80.456  106.599 129.419 1.00 87.51 ? 172 MET A CA  1 
ATOM   1017 C  C   . MET A 1 184 ? 81.694  105.790 129.742 1.00 87.51 ? 172 MET A C   1 
ATOM   1018 O  O   . MET A 1 184 ? 82.361  105.295 128.837 1.00 87.51 ? 172 MET A O   1 
ATOM   1019 C  CB  . MET A 1 184 ? 79.235  105.690 129.358 1.00 87.51 ? 172 MET A CB  1 
ATOM   1020 C  CG  . MET A 1 184 ? 78.530  105.505 130.689 1.00 87.51 ? 172 MET A CG  1 
ATOM   1021 S  SD  . MET A 1 184 ? 76.748  105.727 130.543 1.00 87.51 ? 172 MET A SD  1 
ATOM   1022 C  CE  . MET A 1 184 ? 76.656  107.392 129.889 1.00 87.51 ? 172 MET A CE  1 
ATOM   1023 N  N   . GLU A 1 185 ? 82.000  105.641 131.026 1.00 84.73 ? 173 GLU A N   1 
ATOM   1024 C  CA  . GLU A 1 185 ? 83.161  104.864 131.433 1.00 84.73 ? 173 GLU A CA  1 
ATOM   1025 C  C   . GLU A 1 185 ? 82.956  103.425 131.018 1.00 84.73 ? 173 GLU A C   1 
ATOM   1026 O  O   . GLU A 1 185 ? 81.847  102.915 131.088 1.00 84.73 ? 173 GLU A O   1 
ATOM   1027 C  CB  . GLU A 1 185 ? 83.374  104.964 132.941 1.00 84.73 ? 173 GLU A CB  1 
ATOM   1028 C  CG  . GLU A 1 185 ? 83.450  106.386 133.472 1.00 84.73 ? 173 GLU A CG  1 
ATOM   1029 C  CD  . GLU A 1 185 ? 84.829  107.002 133.338 1.00 84.73 ? 173 GLU A CD  1 
ATOM   1030 O  OE1 . GLU A 1 185 ? 84.982  108.182 133.714 1.00 84.73 ? 173 GLU A OE1 1 
ATOM   1031 O  OE2 . GLU A 1 185 ? 85.759  106.313 132.869 1.00 84.73 ? 173 GLU A OE2 1 
ATOM   1032 N  N   . ASP A 1 186 ? 84.015  102.764 130.579 1.00 72.72 ? 174 ASP A N   1 
ATOM   1033 C  CA  . ASP A 1 186 ? 83.872  101.404 130.067 1.00 72.72 ? 174 ASP A CA  1 
ATOM   1034 C  C   . ASP A 1 186 ? 83.344  100.395 131.081 1.00 72.72 ? 174 ASP A C   1 
ATOM   1035 O  O   . ASP A 1 186 ? 82.624  99.469  130.708 1.00 72.72 ? 174 ASP A O   1 
ATOM   1036 C  CB  . ASP A 1 186 ? 85.179  100.946 129.434 1.00 72.72 ? 174 ASP A CB  1 
ATOM   1037 C  CG  . ASP A 1 186 ? 85.525  101.739 128.192 1.00 72.72 ? 174 ASP A CG  1 
ATOM   1038 O  OD1 . ASP A 1 186 ? 84.624  102.413 127.652 1.00 72.72 ? 174 ASP A OD1 1 
ATOM   1039 O  OD2 . ASP A 1 186 ? 86.691  101.686 127.750 1.00 72.72 ? 174 ASP A OD2 1 
ATOM   1040 N  N   . THR A 1 187 ? 83.688  100.557 132.353 1.00 70.62 ? 175 THR A N   1 
ATOM   1041 C  CA  . THR A 1 187 ? 83.139  99.679  133.375 1.00 70.62 ? 175 THR A CA  1 
ATOM   1042 C  C   . THR A 1 187 ? 81.633  99.865  133.430 1.00 70.62 ? 175 THR A C   1 
ATOM   1043 O  O   . THR A 1 187 ? 80.889  98.909  133.584 1.00 70.62 ? 175 THR A O   1 
ATOM   1044 C  CB  . THR A 1 187 ? 83.732  100.003 134.752 1.00 70.62 ? 175 THR A CB  1 
ATOM   1045 O  OG1 . THR A 1 187 ? 83.436  101.362 135.095 1.00 70.62 ? 175 THR A OG1 1 
ATOM   1046 C  CG2 . THR A 1 187 ? 85.236  99.813  134.741 1.00 70.62 ? 175 THR A CG2 1 
ATOM   1047 N  N   . MET A 1 188 ? 81.171  101.098 133.327 1.00 69.54 ? 176 MET A N   1 
ATOM   1048 C  CA  . MET A 1 188 ? 79.738  101.358 133.285 1.00 69.54 ? 176 MET A CA  1 
ATOM   1049 C  C   . MET A 1 188 ? 79.054  100.797 132.034 1.00 69.54 ? 176 MET A C   1 
ATOM   1050 O  O   . MET A 1 188 ? 77.893  100.416 132.089 1.00 69.54 ? 176 MET A O   1 
ATOM   1051 C  CB  . MET A 1 188 ? 79.465  102.847 133.475 1.00 69.54 ? 176 MET A CB  1 
ATOM   1052 C  CG  . MET A 1 188 ? 80.080  103.403 134.749 1.00 69.54 ? 176 MET A CG  1 
ATOM   1053 S  SD  . MET A 1 188 ? 80.098  105.204 134.846 1.00 69.54 ? 176 MET A SD  1 
ATOM   1054 C  CE  . MET A 1 188 ? 78.359  105.571 135.043 1.00 69.54 ? 176 MET A CE  1 
ATOM   1055 N  N   . ARG A 1 189 ? 79.744  100.760 130.901 1.00 65.76 ? 177 ARG A N   1 
ATOM   1056 C  CA  . ARG A 1 189 ? 79.088  100.319 129.665 1.00 65.76 ? 177 ARG A CA  1 
ATOM   1057 C  C   . ARG A 1 189 ? 78.390  98.978  129.834 1.00 65.76 ? 177 ARG A C   1 
ATOM   1058 O  O   . ARG A 1 189 ? 77.230  98.848  129.485 1.00 65.76 ? 177 ARG A O   1 
ATOM   1059 C  CB  . ARG A 1 189 ? 80.047  100.339 128.476 1.00 65.76 ? 177 ARG A CB  1 
ATOM   1060 C  CG  . ARG A 1 189 ? 80.517  101.741 128.134 1.00 65.76 ? 177 ARG A CG  1 
ATOM   1061 C  CD  . ARG A 1 189 ? 81.033  101.834 126.713 1.00 65.76 ? 177 ARG A CD  1 
ATOM   1062 N  NE  . ARG A 1 189 ? 80.049  101.336 125.761 1.00 65.76 ? 177 ARG A NE  1 
ATOM   1063 C  CZ  . ARG A 1 189 ? 80.179  101.426 124.444 1.00 65.76 ? 177 ARG A CZ  1 
ATOM   1064 N  NH1 . ARG A 1 189 ? 81.248  102.008 123.921 1.00 65.76 ? 177 ARG A NH1 1 
ATOM   1065 N  NH2 . ARG A 1 189 ? 79.236  100.944 123.649 1.00 65.76 ? 177 ARG A NH2 1 
ATOM   1066 N  N   . LYS A 1 190 ? 79.090  97.963  130.315 1.00 64.03 ? 178 LYS A N   1 
ATOM   1067 C  CA  . LYS A 1 190 ? 78.439  96.683  130.611 1.00 64.03 ? 178 LYS A CA  1 
ATOM   1068 C  C   . LYS A 1 190 ? 77.471  96.784  131.789 1.00 64.03 ? 178 LYS A C   1 
ATOM   1069 O  O   . LYS A 1 190 ? 76.442  96.112  131.804 1.00 64.03 ? 178 LYS A O   1 
ATOM   1070 C  CB  . LYS A 1 190 ? 79.475  95.592  130.867 1.00 64.03 ? 178 LYS A CB  1 
ATOM   1071 C  CG  . LYS A 1 190 ? 78.978  94.188  130.574 1.00 64.03 ? 178 LYS A CG  1 
ATOM   1072 C  CD  . LYS A 1 190 ? 80.077  93.161  130.776 1.00 64.03 ? 178 LYS A CD  1 
ATOM   1073 C  CE  . LYS A 1 190 ? 79.616  91.780  130.344 1.00 64.03 ? 178 LYS A CE  1 
ATOM   1074 N  NZ  . LYS A 1 190 ? 78.372  91.371  131.052 1.00 64.03 ? 178 LYS A NZ  1 
ATOM   1075 N  N   . ASN A 1 191 ? 77.831  97.561  132.807 1.00 65.69 ? 179 ASN A N   1 
ATOM   1076 C  CA  . ASN A 1 191 ? 77.012  97.618  134.026 1.00 65.69 ? 179 ASN A CA  1 
ATOM   1077 C  C   . ASN A 1 191 ? 75.944  98.692  134.059 1.00 65.69 ? 179 ASN A C   1 
ATOM   1078 O  O   . ASN A 1 191 ? 76.241  99.821  134.454 1.00 65.69 ? 179 ASN A O   1 
ATOM   1079 C  CB  . ASN A 1 191 ? 77.916  97.783  135.250 1.00 65.69 ? 179 ASN A CB  1 
ATOM   1080 C  CG  . ASN A 1 191 ? 78.981  96.708  135.341 1.00 65.69 ? 179 ASN A CG  1 
ATOM   1081 O  OD1 . ASN A 1 191 ? 78.884  95.663  134.698 1.00 65.69 ? 179 ASN A OD1 1 
ATOM   1082 N  ND2 . ASN A 1 191 ? 80.005  96.959  136.148 1.00 65.69 ? 179 ASN A ND2 1 
ATOM   1083 N  N   . LYS A 1 192 ? 74.733  98.370  133.609 1.00 61.72 ? 180 LYS A N   1 
ATOM   1084 C  CA  . LYS A 1 192 ? 73.589  99.300  133.673 1.00 61.72 ? 180 LYS A CA  1 
ATOM   1085 C  C   . LYS A 1 192 ? 73.565  100.402 132.614 1.00 61.72 ? 180 LYS A C   1 
ATOM   1086 O  O   . LYS A 1 192 ? 72.666  101.242 132.622 1.00 61.72 ? 180 LYS A O   1 
ATOM   1087 C  CB  . LYS A 1 192 ? 73.371  99.887  135.083 1.00 61.72 ? 180 LYS A CB  1 
ATOM   1088 C  CG  . LYS A 1 192 ? 73.167  98.859  136.186 1.00 61.72 ? 180 LYS A CG  1 
ATOM   1089 C  CD  . LYS A 1 192 ? 71.802  98.204  136.092 1.00 61.72 ? 180 LYS A CD  1 
ATOM   1090 C  CE  . LYS A 1 192 ? 71.642  97.106  137.130 1.00 61.72 ? 180 LYS A CE  1 
ATOM   1091 N  NZ  . LYS A 1 192 ? 70.314  96.441  137.025 1.00 61.72 ? 180 LYS A NZ  1 
ATOM   1092 N  N   . SER A 1 193 ? 74.529  100.406 131.701 1.00 64.32 ? 181 SER A N   1 
ATOM   1093 C  CA  . SER A 1 193 ? 74.501  101.399 130.631 1.00 64.32 ? 181 SER A CA  1 
ATOM   1094 C  C   . SER A 1 193 ? 73.996  100.885 129.293 1.00 64.32 ? 181 SER A C   1 
ATOM   1095 O  O   . SER A 1 193 ? 73.315  101.612 128.572 1.00 64.32 ? 181 SER A O   1 
ATOM   1096 C  CB  . SER A 1 193 ? 75.864  102.067 130.448 1.00 64.32 ? 181 SER A CB  1 
ATOM   1097 O  OG  . SER A 1 193 ? 76.223  102.806 131.602 1.00 64.32 ? 181 SER A OG  1 
ATOM   1098 N  N   . VAL A 1 194 ? 74.314  99.643  128.947 1.00 59.06 ? 182 VAL A N   1 
ATOM   1099 C  CA  . VAL A 1 194 ? 73.921  99.178  127.622 1.00 59.06 ? 182 VAL A CA  1 
ATOM   1100 C  C   . VAL A 1 194 ? 72.623  98.401  127.610 1.00 59.06 ? 182 VAL A C   1 
ATOM   1101 O  O   . VAL A 1 194 ? 72.584  97.238  128.016 1.00 59.06 ? 182 VAL A O   1 
ATOM   1102 C  CB  . VAL A 1 194 ? 75.054  98.415  126.888 1.00 59.06 ? 182 VAL A CB  1 
ATOM   1103 C  CG1 . VAL A 1 194 ? 74.532  97.769  125.611 1.00 59.06 ? 182 VAL A CG1 1 
ATOM   1104 C  CG2 . VAL A 1 194 ? 76.178  99.376  126.532 1.00 59.06 ? 182 VAL A CG2 1 
ATOM   1105 N  N   . TRP A 1 195 ? 71.551  99.055  127.173 1.00 56.84 ? 183 TRP A N   1 
ATOM   1106 C  CA  . TRP A 1 195 ? 70.257  98.384  127.049 1.00 56.84 ? 183 TRP A CA  1 
ATOM   1107 C  C   . TRP A 1 195 ? 69.829  97.670  128.321 1.00 56.84 ? 183 TRP A C   1 
ATOM   1108 O  O   . TRP A 1 195 ? 69.328  96.548  128.270 1.00 56.84 ? 183 TRP A O   1 
ATOM   1109 C  CB  . TRP A 1 195 ? 70.226  97.473  125.817 1.00 56.84 ? 183 TRP A CB  1 
ATOM   1110 C  CG  . TRP A 1 195 ? 70.442  98.242  124.551 1.00 56.84 ? 183 TRP A CG  1 
ATOM   1111 C  CD1 . TRP A 1 195 ? 69.502  98.929  123.843 1.00 56.84 ? 183 TRP A CD1 1 
ATOM   1112 C  CD2 . TRP A 1 195 ? 71.680  98.420  123.852 1.00 56.84 ? 183 TRP A CD2 1 
ATOM   1113 N  NE1 . TRP A 1 195 ? 70.075  99.520  122.744 1.00 56.84 ? 183 TRP A NE1 1 
ATOM   1114 C  CE2 . TRP A 1 195 ? 71.411  99.222  122.726 1.00 56.84 ? 183 TRP A CE2 1 
ATOM   1115 C  CE3 . TRP A 1 195 ? 72.988  97.974  124.065 1.00 56.84 ? 183 TRP A CE3 1 
ATOM   1116 C  CZ2 . TRP A 1 195 ? 72.401  99.588  121.817 1.00 56.84 ? 183 TRP A CZ2 1 
ATOM   1117 C  CZ3 . TRP A 1 195 ? 73.968  98.340  123.164 1.00 56.84 ? 183 TRP A CZ3 1 
ATOM   1118 C  CH2 . TRP A 1 195 ? 73.670  99.139  122.054 1.00 56.84 ? 183 TRP A CH2 1 
ATOM   1119 N  N   . ILE A 1 196 ? 70.028  98.319  129.463 1.00 60.37 ? 184 ILE A N   1 
ATOM   1120 C  CA  . ILE A 1 196 ? 69.633  97.715  130.727 1.00 60.37 ? 184 ILE A CA  1 
ATOM   1121 C  C   . ILE A 1 196 ? 68.366  98.362  131.277 1.00 60.37 ? 184 ILE A C   1 
ATOM   1122 O  O   . ILE A 1 196 ? 67.304  97.740  131.276 1.00 60.37 ? 184 ILE A O   1 
ATOM   1123 C  CB  . ILE A 1 196 ? 70.752  97.762  131.782 1.00 60.37 ? 184 ILE A CB  1 
ATOM   1124 C  CG1 . ILE A 1 196 ? 72.018  97.094  131.250 1.00 60.37 ? 184 ILE A CG1 1 
ATOM   1125 C  CG2 . ILE A 1 196 ? 70.309  97.039  133.042 1.00 60.37 ? 184 ILE A CG2 1 
ATOM   1126 C  CD1 . ILE A 1 196 ? 71.902  95.592  131.113 1.00 60.37 ? 184 ILE A CD1 1 
ATOM   1127 N  N   . THR A 1 197 ? 68.465  99.608  131.738 1.00 60.77 ? 185 THR A N   1 
ATOM   1128 C  CA  . THR A 1 197 ? 67.273  100.290 132.230 1.00 60.77 ? 185 THR A CA  1 
ATOM   1129 C  C   . THR A 1 197 ? 66.884  101.324 131.201 1.00 60.77 ? 185 THR A C   1 
ATOM   1130 O  O   . THR A 1 197 ? 65.704  101.477 130.887 1.00 60.77 ? 185 THR A O   1 
ATOM   1131 C  CB  . THR A 1 197 ? 67.528  100.972 133.583 1.00 60.77 ? 185 THR A CB  1 
ATOM   1132 O  OG1 . THR A 1 197 ? 68.595  101.919 133.452 1.00 60.77 ? 185 THR A OG1 1 
ATOM   1133 C  CG2 . THR A 1 197 ? 67.902  99.938  134.632 1.00 60.77 ? 185 THR A CG2 1 
ATOM   1134 N  N   . ILE A 1 198 ? 67.867  102.038 130.667 1.00 56.46 ? 186 ILE A N   1 
ATOM   1135 C  CA  . ILE A 1 198 ? 67.597  102.979 129.595 1.00 56.46 ? 186 ILE A CA  1 
ATOM   1136 C  C   . ILE A 1 198 ? 68.448  102.427 128.480 1.00 56.46 ? 186 ILE A C   1 
ATOM   1137 O  O   . ILE A 1 198 ? 69.638  102.211 128.678 1.00 56.46 ? 186 ILE A O   1 
ATOM   1138 C  CB  . ILE A 1 198 ? 68.071  104.396 129.945 1.00 56.46 ? 186 ILE A CB  1 
ATOM   1139 C  CG1 . ILE A 1 198 ? 67.470  104.851 131.276 1.00 56.46 ? 186 ILE A CG1 1 
ATOM   1140 C  CG2 . ILE A 1 198 ? 67.710  105.372 128.834 1.00 56.46 ? 186 ILE A CG2 1 
ATOM   1141 C  CD1 . ILE A 1 198 ? 67.916  106.230 131.709 1.00 56.46 ? 186 ILE A CD1 1 
ATOM   1142 N  N   . SER A 1 199 ? 67.873  102.204 127.306 1.00 58.81 ? 187 SER A N   1 
ATOM   1143 C  CA  . SER A 1 199 ? 68.640  101.567 126.241 1.00 58.81 ? 187 SER A CA  1 
ATOM   1144 C  C   . SER A 1 199 ? 69.849  102.401 125.841 1.00 58.81 ? 187 SER A C   1 
ATOM   1145 O  O   . SER A 1 199 ? 69.750  103.620 125.693 1.00 58.81 ? 187 SER A O   1 
ATOM   1146 C  CB  . SER A 1 199 ? 67.747  101.309 125.027 1.00 58.81 ? 187 SER A CB  1 
ATOM   1147 O  OG  . SER A 1 199 ? 67.190  102.516 124.538 1.00 58.81 ? 187 SER A OG  1 
ATOM   1148 N  N   . SER A 1 200 ? 70.995  101.756 125.640 1.00 55.61 ? 188 SER A N   1 
ATOM   1149 C  CA  . SER A 1 200 ? 72.220  102.479 125.280 1.00 55.61 ? 188 SER A CA  1 
ATOM   1150 C  C   . SER A 1 200 ? 72.079  103.338 124.040 1.00 55.61 ? 188 SER A C   1 
ATOM   1151 O  O   . SER A 1 200 ? 71.944  102.819 122.933 1.00 55.61 ? 188 SER A O   1 
ATOM   1152 C  CB  . SER A 1 200 ? 73.374  101.513 125.059 1.00 55.61 ? 188 SER A CB  1 
ATOM   1153 O  OG  . SER A 1 200 ? 74.490  102.174 124.491 1.00 55.61 ? 188 SER A OG  1 
ATOM   1154 N  N   . THR A 1 201 ? 72.122  104.652 124.216 1.00 57.44 ? 189 THR A N   1 
ATOM   1155 C  CA  . THR A 1 201 ? 72.056  105.542 123.068 1.00 57.44 ? 189 THR A CA  1 
ATOM   1156 C  C   . THR A 1 201 ? 73.444  105.758 122.490 1.00 57.44 ? 189 THR A C   1 
ATOM   1157 O  O   . THR A 1 201 ? 74.042  106.810 122.709 1.00 57.44 ? 189 THR A O   1 
ATOM   1158 C  CB  . THR A 1 201 ? 71.439  106.899 123.442 1.00 57.44 ? 189 THR A CB  1 
ATOM   1159 O  OG1 . THR A 1 201 ? 70.397  106.701 124.405 1.00 57.44 ? 189 THR A OG1 1 
ATOM   1160 C  CG2 . THR A 1 201 ? 70.865  107.585 122.208 1.00 57.44 ? 189 THR A CG2 1 
ATOM   1161 N  N   . ASN A 1 202 ? 73.979  104.759 121.793 1.00 71.16 ? 190 ASN A N   1 
ATOM   1162 C  CA  . ASN A 1 202 ? 75.276  104.913 121.131 1.00 71.16 ? 190 ASN A CA  1 
ATOM   1163 C  C   . ASN A 1 202 ? 76.391  105.393 122.052 1.00 71.16 ? 190 ASN A C   1 
ATOM   1164 O  O   . ASN A 1 202 ? 77.141  106.297 121.691 1.00 71.16 ? 190 ASN A O   1 
ATOM   1165 C  CB  . ASN A 1 202 ? 75.161  105.839 119.916 1.00 71.16 ? 190 ASN A CB  1 
ATOM   1166 C  CG  . ASN A 1 202 ? 74.138  105.356 118.907 1.00 71.16 ? 190 ASN A CG  1 
ATOM   1167 O  OD1 . ASN A 1 202 ? 73.603  104.254 119.024 1.00 71.16 ? 190 ASN A OD1 1 
ATOM   1168 N  ND2 . ASN A 1 202 ? 73.863  106.181 117.904 1.00 71.16 ? 190 ASN A ND2 1 
ATOM   1169 N  N   . PHE A 1 203 ? 76.527  104.780 123.223 1.00 80.01 ? 191 PHE A N   1 
ATOM   1170 C  CA  . PHE A 1 203 ? 77.562  105.196 124.173 1.00 80.01 ? 191 PHE A CA  1 
ATOM   1171 C  C   . PHE A 1 203 ? 78.962  104.917 123.633 1.00 80.01 ? 191 PHE A C   1 
ATOM   1172 O  O   . PHE A 1 203 ? 79.152  103.971 122.870 1.00 80.01 ? 191 PHE A O   1 
ATOM   1173 C  CB  . PHE A 1 203 ? 77.346  104.547 125.541 1.00 80.01 ? 191 PHE A CB  1 
ATOM   1174 C  CG  . PHE A 1 203 ? 76.072  104.977 126.213 1.00 80.01 ? 191 PHE A CG  1 
ATOM   1175 C  CD1 . PHE A 1 203 ? 75.493  106.199 125.909 1.00 80.01 ? 191 PHE A CD1 1 
ATOM   1176 C  CD2 . PHE A 1 203 ? 75.458  104.167 127.150 1.00 80.01 ? 191 PHE A CD2 1 
ATOM   1177 C  CE1 . PHE A 1 203 ? 74.323  106.602 126.520 1.00 80.01 ? 191 PHE A CE1 1 
ATOM   1178 C  CE2 . PHE A 1 203 ? 74.288  104.567 127.767 1.00 80.01 ? 191 PHE A CE2 1 
ATOM   1179 C  CZ  . PHE A 1 203 ? 73.719  105.784 127.452 1.00 80.01 ? 191 PHE A CZ  1 
ATOM   1180 N  N   . THR A 1 204 ? 79.941  105.738 124.009 1.00 86.05 ? 192 THR A N   1 
ATOM   1181 C  CA  . THR A 1 204 ? 81.295  105.585 123.455 1.00 86.05 ? 192 THR A CA  1 
ATOM   1182 C  C   . THR A 1 204 ? 82.437  105.652 124.471 1.00 86.05 ? 192 THR A C   1 
ATOM   1183 O  O   . THR A 1 204 ? 82.275  106.205 125.557 1.00 86.05 ? 192 THR A O   1 
ATOM   1184 C  CB  . THR A 1 204 ? 81.545  106.579 122.298 1.00 86.05 ? 192 THR A CB  1 
ATOM   1185 O  OG1 . THR A 1 204 ? 81.380  107.923 122.764 1.00 86.05 ? 192 THR A OG1 1 
ATOM   1186 C  CG2 . THR A 1 204 ? 80.582  106.322 121.153 1.00 86.05 ? 192 THR A CG2 1 
ATOM   1187 N  N   . SER A 1 205 ? 83.588  105.079 124.123 1.00 88.52 ? 193 SER A N   1 
ATOM   1188 C  CA  . SER A 1 205 ? 84.734  105.045 125.041 1.00 88.52 ? 193 SER A CA  1 
ATOM   1189 C  C   . SER A 1 205 ? 85.429  106.405 125.336 1.00 88.52 ? 193 SER A C   1 
ATOM   1190 O  O   . SER A 1 205 ? 85.606  107.196 124.413 1.00 88.52 ? 193 SER A O   1 
ATOM   1191 C  CB  . SER A 1 205 ? 85.770  104.036 124.536 1.00 88.52 ? 193 SER A CB  1 
ATOM   1192 O  OG  . SER A 1 205 ? 86.906  103.986 125.381 1.00 88.52 ? 193 SER A OG  1 
ATOM   1193 N  N   . PRO A 1 206 ? 85.834  106.681 126.618 1.00 92.91 ? 194 PRO A N   1 
ATOM   1194 C  CA  . PRO A 1 206 ? 86.553  107.931 126.852 1.00 92.91 ? 194 PRO A CA  1 
ATOM   1195 C  C   . PRO A 1 206 ? 87.784  108.030 125.970 1.00 92.91 ? 194 PRO A C   1 
ATOM   1196 O  O   . PRO A 1 206 ? 88.082  109.112 125.487 1.00 92.91 ? 194 PRO A O   1 
ATOM   1197 C  CB  . PRO A 1 206 ? 86.960  107.817 128.315 1.00 92.91 ? 194 PRO A CB  1 
ATOM   1198 C  CG  . PRO A 1 206 ? 85.934  106.938 128.930 1.00 92.91 ? 194 PRO A CG  1 
ATOM   1199 C  CD  . PRO A 1 206 ? 85.589  105.941 127.867 1.00 92.91 ? 194 PRO A CD  1 
ATOM   1200 N  N   . VAL A 1 207 ? 88.494  106.927 125.770 1.00 92.58 ? 195 VAL A N   1 
ATOM   1201 C  CA  . VAL A 1 207 ? 89.702  106.929 124.958 1.00 92.58 ? 195 VAL A CA  1 
ATOM   1202 C  C   . VAL A 1 207 ? 89.430  107.299 123.507 1.00 92.58 ? 195 VAL A C   1 
ATOM   1203 O  O   . VAL A 1 207 ? 90.175  108.075 122.917 1.00 92.58 ? 195 VAL A O   1 
ATOM   1204 C  CB  . VAL A 1 207 ? 90.392  105.551 125.015 1.00 92.58 ? 195 VAL A CB  1 
ATOM   1205 C  CG1 . VAL A 1 207 ? 91.812  105.638 124.479 1.00 92.58 ? 195 VAL A CG1 1 
ATOM   1206 C  CG2 . VAL A 1 207 ? 90.406  105.035 126.442 1.00 92.58 ? 195 VAL A CG2 1 
ATOM   1207 N  N   . ILE A 1 208 ? 88.366  106.760 122.926 1.00 90.72 ? 196 ILE A N   1 
ATOM   1208 C  CA  . ILE A 1 208 ? 88.007  107.097 121.552 1.00 90.72 ? 196 ILE A CA  1 
ATOM   1209 C  C   . ILE A 1 208 ? 87.633  108.558 121.433 1.00 90.72 ? 196 ILE A C   1 
ATOM   1210 O  O   . ILE A 1 208 ? 88.034  109.231 120.494 1.00 90.72 ? 196 ILE A O   1 
ATOM   1211 C  CB  . ILE A 1 208 ? 86.852  106.223 121.041 1.00 90.72 ? 196 ILE A CB  1 
ATOM   1212 C  CG1 . ILE A 1 208 ? 87.239  104.750 121.108 1.00 90.72 ? 196 ILE A CG1 1 
ATOM   1213 C  CG2 . ILE A 1 208 ? 86.484  106.582 119.611 1.00 90.72 ? 196 ILE A CG2 1 
ATOM   1214 C  CD1 . ILE A 1 208 ? 86.203  103.840 120.494 1.00 90.72 ? 196 ILE A CD1 1 
ATOM   1215 N  N   . GLU A 1 209 ? 86.884  109.062 122.401 1.00 94.13 ? 197 GLU A N   1 
ATOM   1216 C  CA  . GLU A 1 209 ? 86.498  110.461 122.393 1.00 94.13 ? 197 GLU A CA  1 
ATOM   1217 C  C   . GLU A 1 209 ? 87.693  111.372 122.503 1.00 94.13 ? 197 GLU A C   1 
ATOM   1218 O  O   . GLU A 1 209 ? 87.743  112.402 121.865 1.00 94.13 ? 197 GLU A O   1 
ATOM   1219 C  CB  . GLU A 1 209 ? 85.521  110.742 123.521 1.00 94.13 ? 197 GLU A CB  1 
ATOM   1220 C  CG  . GLU A 1 209 ? 84.219  109.994 123.371 1.00 94.13 ? 197 GLU A CG  1 
ATOM   1221 C  CD  . GLU A 1 209 ? 83.040  110.924 123.390 1.00 94.13 ? 197 GLU A CD  1 
ATOM   1222 O  OE1 . GLU A 1 209 ? 81.913  110.467 123.121 1.00 94.13 ? 197 GLU A OE1 1 
ATOM   1223 O  OE2 . GLU A 1 209 ? 83.254  112.116 123.676 1.00 94.13 ? 197 GLU A OE2 1 
ATOM   1224 N  N   . PHE A 1 210 ? 88.662  111.003 123.320 1.00 95.91 ? 198 PHE A N   1 
ATOM   1225 C  CA  . PHE A 1 210 ? 89.860  111.802 123.416 1.00 95.91 ? 198 PHE A CA  1 
ATOM   1226 C  C   . PHE A 1 210 ? 90.582  111.852 122.072 1.00 95.91 ? 198 PHE A C   1 
ATOM   1227 O  O   . PHE A 1 210 ? 91.009  112.910 121.641 1.00 95.91 ? 198 PHE A O   1 
ATOM   1228 C  CB  . PHE A 1 210 ? 90.777  111.231 124.502 1.00 95.91 ? 198 PHE A CB  1 
ATOM   1229 C  CG  . PHE A 1 210 ? 92.070  111.970 124.665 1.00 95.91 ? 198 PHE A CG  1 
ATOM   1230 C  CD1 . PHE A 1 210 ? 92.115  113.160 125.357 1.00 95.91 ? 198 PHE A CD1 1 
ATOM   1231 C  CD2 . PHE A 1 210 ? 93.244  111.462 124.145 1.00 95.91 ? 198 PHE A CD2 1 
ATOM   1232 C  CE1 . PHE A 1 210 ? 93.301  113.843 125.512 1.00 95.91 ? 198 PHE A CE1 1 
ATOM   1233 C  CE2 . PHE A 1 210 ? 94.434  112.142 124.297 1.00 95.91 ? 198 PHE A CE2 1 
ATOM   1234 C  CZ  . PHE A 1 210 ? 94.464  113.333 124.981 1.00 95.91 ? 198 PHE A CZ  1 
ATOM   1235 N  N   . TRP A 1 211 ? 90.721  110.716 121.405 1.00 95.24 ? 199 TRP A N   1 
ATOM   1236 C  CA  . TRP A 1 211 ? 91.418  110.700 120.135 1.00 95.24 ? 199 TRP A CA  1 
ATOM   1237 C  C   . TRP A 1 211 ? 90.691  111.453 119.049 1.00 95.24 ? 199 TRP A C   1 
ATOM   1238 O  O   . TRP A 1 211 ? 91.276  112.274 118.362 1.00 95.24 ? 199 TRP A O   1 
ATOM   1239 C  CB  . TRP A 1 211 ? 91.647  109.251 119.701 1.00 95.24 ? 199 TRP A CB  1 
ATOM   1240 C  CG  . TRP A 1 211 ? 92.037  109.051 118.265 1.00 95.24 ? 199 TRP A CG  1 
ATOM   1241 C  CD1 . TRP A 1 211 ? 91.276  108.484 117.286 1.00 95.24 ? 199 TRP A CD1 1 
ATOM   1242 C  CD2 . TRP A 1 211 ? 93.284  109.398 117.650 1.00 95.24 ? 199 TRP A CD2 1 
ATOM   1243 N  NE1 . TRP A 1 211 ? 91.966  108.461 116.103 1.00 95.24 ? 199 TRP A NE1 1 
ATOM   1244 C  CE2 . TRP A 1 211 ? 93.202  109.017 116.300 1.00 95.24 ? 199 TRP A CE2 1 
ATOM   1245 C  CE3 . TRP A 1 211 ? 94.457  110.001 118.109 1.00 95.24 ? 199 TRP A CE3 1 
ATOM   1246 C  CZ2 . TRP A 1 211 ? 94.249  109.217 115.406 1.00 95.24 ? 199 TRP A CZ2 1 
ATOM   1247 C  CZ3 . TRP A 1 211 ? 95.491  110.196 117.223 1.00 95.24 ? 199 TRP A CZ3 1 
ATOM   1248 C  CH2 . TRP A 1 211 ? 95.382  109.804 115.887 1.00 95.24 ? 199 TRP A CH2 1 
ATOM   1249 N  N   . GLU A 1 212 ? 89.401  111.209 118.903 1.00 94.09 ? 200 GLU A N   1 
ATOM   1250 C  CA  . GLU A 1 212 ? 88.656  111.838 117.829 1.00 94.09 ? 200 GLU A CA  1 
ATOM   1251 C  C   . GLU A 1 212 ? 88.341  113.284 118.121 1.00 94.09 ? 200 GLU A C   1 
ATOM   1252 O  O   . GLU A 1 212 ? 88.301  114.102 117.215 1.00 94.09 ? 200 GLU A O   1 
ATOM   1253 C  CB  . GLU A 1 212 ? 87.383  111.057 117.539 1.00 94.09 ? 200 GLU A CB  1 
ATOM   1254 C  CG  . GLU A 1 212 ? 87.641  109.703 116.908 1.00 94.09 ? 200 GLU A CG  1 
ATOM   1255 C  CD  . GLU A 1 212 ? 86.362  108.966 116.587 1.00 94.09 ? 200 GLU A CD  1 
ATOM   1256 O  OE1 . GLU A 1 212 ? 86.436  107.884 115.968 1.00 94.09 ? 200 GLU A OE1 1 
ATOM   1257 O  OE2 . GLU A 1 212 ? 85.281  109.471 116.954 1.00 94.09 ? 200 GLU A OE2 1 
ATOM   1258 N  N   . ARG A 1 213 ? 88.098  113.609 119.378 1.00 95.75 ? 201 ARG A N   1 
ATOM   1259 C  CA  . ARG A 1 213 ? 87.727  114.967 119.701 1.00 95.75 ? 201 ARG A CA  1 
ATOM   1260 C  C   . ARG A 1 213 ? 88.829  115.848 120.278 1.00 95.75 ? 201 ARG A C   1 
ATOM   1261 O  O   . ARG A 1 213 ? 89.045  116.941 119.776 1.00 95.75 ? 201 ARG A O   1 
ATOM   1262 C  CB  . ARG A 1 213 ? 86.513  114.975 120.622 1.00 95.75 ? 201 ARG A CB  1 
ATOM   1263 C  CG  . ARG A 1 213 ? 85.338  114.190 120.078 1.00 95.75 ? 201 ARG A CG  1 
ATOM   1264 C  CD  . ARG A 1 213 ? 84.107  114.393 120.936 1.00 95.75 ? 201 ARG A CD  1 
ATOM   1265 N  NE  . ARG A 1 213 ? 83.113  115.234 120.275 1.00 95.75 ? 201 ARG A NE  1 
ATOM   1266 C  CZ  . ARG A 1 213 ? 82.947  116.534 120.503 1.00 95.75 ? 201 ARG A CZ  1 
ATOM   1267 N  NH1 . ARG A 1 213 ? 83.707  117.164 121.386 1.00 95.75 ? 201 ARG A NH1 1 
ATOM   1268 N  NH2 . ARG A 1 213 ? 82.012  117.204 119.847 1.00 95.75 ? 201 ARG A NH2 1 
ATOM   1269 N  N   . ASN A 1 214 ? 89.516  115.435 121.332 1.00 96.70 ? 202 ASN A N   1 
ATOM   1270 C  CA  . ASN A 1 214 ? 90.587  116.300 121.802 1.00 96.70 ? 202 ASN A CA  1 
ATOM   1271 C  C   . ASN A 1 214 ? 91.805  116.364 120.885 1.00 96.70 ? 202 ASN A C   1 
ATOM   1272 O  O   . ASN A 1 214 ? 92.268  117.446 120.537 1.00 96.70 ? 202 ASN A O   1 
ATOM   1273 C  CB  . ASN A 1 214 ? 91.027  115.924 123.216 1.00 96.70 ? 202 ASN A CB  1 
ATOM   1274 C  CG  . ASN A 1 214 ? 91.973  116.940 123.819 1.00 96.70 ? 202 ASN A CG  1 
ATOM   1275 O  OD1 . ASN A 1 214 ? 91.556  118.017 124.235 1.00 96.70 ? 202 ASN A OD1 1 
ATOM   1276 N  ND2 . ASN A 1 214 ? 93.254  116.606 123.863 1.00 96.70 ? 202 ASN A ND2 1 
ATOM   1277 N  N   . VAL A 1 215 ? 92.324  115.211 120.488 1.00 97.19 ? 203 VAL A N   1 
ATOM   1278 C  CA  . VAL A 1 215 ? 93.493  115.191 119.624 1.00 97.19 ? 203 VAL A CA  1 
ATOM   1279 C  C   . VAL A 1 215 ? 93.215  115.626 118.209 1.00 97.19 ? 203 VAL A C   1 
ATOM   1280 O  O   . VAL A 1 215 ? 93.948  116.429 117.651 1.00 97.19 ? 203 VAL A O   1 
ATOM   1281 C  CB  . VAL A 1 215 ? 94.170  113.809 119.615 1.00 97.19 ? 203 VAL A CB  1 
ATOM   1282 C  CG1 . VAL A 1 215 ? 95.494  113.859 118.869 1.00 97.19 ? 203 VAL A CG1 1 
ATOM   1283 C  CG2 . VAL A 1 215 ? 94.395  113.338 121.034 1.00 97.19 ? 203 VAL A CG2 1 
ATOM   1284 N  N   . LEU A 1 216 ? 92.134  115.125 117.630 1.00 96.16 ? 204 LEU A N   1 
ATOM   1285 C  CA  . LEU A 1 216 ? 91.865  115.411 116.232 1.00 96.16 ? 204 LEU A CA  1 
ATOM   1286 C  C   . LEU A 1 216 ? 90.836  116.480 115.971 1.00 96.16 ? 204 LEU A C   1 
ATOM   1287 O  O   . LEU A 1 216 ? 90.960  117.193 114.979 1.00 96.16 ? 204 LEU A O   1 
ATOM   1288 C  CB  . LEU A 1 216 ? 91.429  114.131 115.511 1.00 96.16 ? 204 LEU A CB  1 
ATOM   1289 C  CG  . LEU A 1 216 ? 92.353  112.927 115.354 1.00 96.16 ? 204 LEU A CG  1 
ATOM   1290 C  CD1 . LEU A 1 216 ? 91.614  111.864 114.558 1.00 96.16 ? 204 LEU A CD1 1 
ATOM   1291 C  CD2 . LEU A 1 216 ? 93.650  113.309 114.662 1.00 96.16 ? 204 LEU A CD2 1 
ATOM   1292 N  N   . SER A 1 217 ? 89.828  116.602 116.833 1.00 96.60 ? 205 SER A N   1 
ATOM   1293 C  CA  . SER A 1 217 ? 88.731  117.535 116.579 1.00 96.60 ? 205 SER A CA  1 
ATOM   1294 C  C   . SER A 1 217 ? 88.244  117.215 115.191 1.00 96.60 ? 205 SER A C   1 
ATOM   1295 O  O   . SER A 1 217 ? 88.096  118.110 114.367 1.00 96.60 ? 205 SER A O   1 
ATOM   1296 C  CB  . SER A 1 217 ? 89.151  118.989 116.734 1.00 96.60 ? 205 SER A CB  1 
ATOM   1297 O  OG  . SER A 1 217 ? 89.656  119.233 118.033 1.00 96.60 ? 205 SER A OG  1 
ATOM   1298 N  N   . LEU A 1 218 ? 88.013  115.933 114.928 1.00 94.70 ? 206 LEU A N   1 
ATOM   1299 C  CA  . LEU A 1 218 ? 87.627  115.489 113.593 1.00 94.70 ? 206 LEU A CA  1 
ATOM   1300 C  C   . LEU A 1 218 ? 86.436  116.195 112.975 1.00 94.70 ? 206 LEU A C   1 
ATOM   1301 O  O   . LEU A 1 218 ? 85.366  116.262 113.573 1.00 94.70 ? 206 LEU A O   1 
ATOM   1302 C  CB  . LEU A 1 218 ? 87.418  113.973 113.599 1.00 94.70 ? 206 LEU A CB  1 
ATOM   1303 C  CG  . LEU A 1 218 ? 87.440  113.234 112.267 1.00 94.70 ? 206 LEU A CG  1 
ATOM   1304 C  CD1 . LEU A 1 218 ? 88.799  113.391 111.612 1.00 94.70 ? 206 LEU A CD1 1 
ATOM   1305 C  CD2 . LEU A 1 218 ? 87.123  111.768 112.496 1.00 94.70 ? 206 LEU A CD2 1 
ATOM   1306 N  N   . SER A 1 219 ? 86.620  116.718 111.771 1.00 96.33 ? 207 SER A N   1 
ATOM   1307 C  CA  . SER A 1 219 ? 85.549  117.400 111.065 1.00 96.33 ? 207 SER A CA  1 
ATOM   1308 C  C   . SER A 1 219 ? 84.621  116.372 110.445 1.00 96.33 ? 207 SER A C   1 
ATOM   1309 O  O   . SER A 1 219 ? 84.944  115.188 110.412 1.00 96.33 ? 207 SER A O   1 
ATOM   1310 C  CB  . SER A 1 219 ? 86.138  118.282 109.979 1.00 96.33 ? 207 SER A CB  1 
ATOM   1311 O  OG  . SER A 1 219 ? 86.446  117.511 108.839 1.00 96.33 ? 207 SER A OG  1 
ATOM   1312 N  N   . PRO A 1 220 ? 83.458  116.811 109.944 1.00 95.06 ? 208 PRO A N   1 
ATOM   1313 C  CA  . PRO A 1 220 ? 82.589  115.850 109.262 1.00 95.06 ? 208 PRO A CA  1 
ATOM   1314 C  C   . PRO A 1 220 ? 83.245  115.200 108.056 1.00 95.06 ? 208 PRO A C   1 
ATOM   1315 O  O   . PRO A 1 220 ? 82.998  114.026 107.817 1.00 95.06 ? 208 PRO A O   1 
ATOM   1316 C  CB  . PRO A 1 220 ? 81.421  116.714 108.806 1.00 95.06 ? 208 PRO A CB  1 
ATOM   1317 C  CG  . PRO A 1 220 ? 81.341  117.790 109.828 1.00 95.06 ? 208 PRO A CG  1 
ATOM   1318 C  CD  . PRO A 1 220 ? 82.759  118.079 110.225 1.00 95.06 ? 208 PRO A CD  1 
ATOM   1319 N  N   . GLY A 1 221 ? 84.042  115.934 107.295 1.00 95.39 ? 209 GLY A N   1 
ATOM   1320 C  CA  . GLY A 1 221 ? 84.624  115.386 106.087 1.00 95.39 ? 209 GLY A CA  1 
ATOM   1321 C  C   . GLY A 1 221 ? 85.908  116.032 105.640 1.00 95.39 ? 209 GLY A C   1 
ATOM   1322 O  O   . GLY A 1 221 ? 86.309  117.041 106.190 1.00 95.39 ? 209 GLY A O   1 
ATOM   1323 N  N   . ILE A 1 222 ? 86.586  115.433 104.669 1.00 96.63 ? 210 ILE A N   1 
ATOM   1324 C  CA  . ILE A 1 222 ? 87.783  116.067 104.145 1.00 96.63 ? 210 ILE A CA  1 
ATOM   1325 C  C   . ILE A 1 222 ? 87.336  117.417 103.622 1.00 96.63 ? 210 ILE A C   1 
ATOM   1326 O  O   . ILE A 1 222 ? 88.083  118.381 103.713 1.00 96.63 ? 210 ILE A O   1 
ATOM   1327 C  CB  . ILE A 1 222 ? 88.485  115.216 103.060 1.00 96.63 ? 210 ILE A CB  1 
ATOM   1328 C  CG1 . ILE A 1 222 ? 89.857  115.799 102.717 1.00 96.63 ? 210 ILE A CG1 1 
ATOM   1329 C  CG2 . ILE A 1 222 ? 87.633  115.079 101.809 1.00 96.63 ? 210 ILE A CG2 1 
ATOM   1330 C  CD1 . ILE A 1 222 ? 90.605  115.011 101.666 1.00 96.63 ? 210 ILE A CD1 1 
ATOM   1331 N  N   . ASP A 1 223 ? 86.078  117.518 103.200 1.00 96.23 ? 211 ASP A N   1 
ATOM   1332 C  CA  . ASP A 1 223 ? 85.566  118.756 102.611 1.00 96.23 ? 211 ASP A CA  1 
ATOM   1333 C  C   . ASP A 1 223 ? 85.620  119.941 103.553 1.00 96.23 ? 211 ASP A C   1 
ATOM   1334 O  O   . ASP A 1 223 ? 85.879  121.061 103.125 1.00 96.23 ? 211 ASP A O   1 
ATOM   1335 C  CB  . ASP A 1 223 ? 84.117  118.559 102.164 1.00 96.23 ? 211 ASP A CB  1 
ATOM   1336 C  CG  . ASP A 1 223 ? 83.995  117.612 100.997 1.00 96.23 ? 211 ASP A CG  1 
ATOM   1337 O  OD1 . ASP A 1 223 ? 85.024  117.342 100.350 1.00 96.23 ? 211 ASP A OD1 1 
ATOM   1338 O  OD2 . ASP A 1 223 ? 82.872  117.135 100.727 1.00 96.23 ? 211 ASP A OD2 1 
ATOM   1339 N  N   . HIS A 1 224 ? 85.327  119.703 104.824 1.00 96.69 ? 212 HIS A N   1 
ATOM   1340 C  CA  . HIS A 1 224 ? 85.588  120.683 105.866 1.00 96.69 ? 212 HIS A CA  1 
ATOM   1341 C  C   . HIS A 1 224 ? 87.021  120.554 106.365 1.00 96.69 ? 212 HIS A C   1 
ATOM   1342 O  O   . HIS A 1 224 ? 87.326  119.656 107.143 1.00 96.69 ? 212 HIS A O   1 
ATOM   1343 C  CB  . HIS A 1 224 ? 84.621  120.470 107.028 1.00 96.69 ? 212 HIS A CB  1 
ATOM   1344 C  CG  . HIS A 1 224 ? 83.229  120.131 106.598 1.00 96.69 ? 212 HIS A CG  1 
ATOM   1345 N  ND1 . HIS A 1 224 ? 82.261  121.089 106.389 1.00 96.69 ? 212 HIS A ND1 1 
ATOM   1346 C  CD2 . HIS A 1 224 ? 82.642  118.940 106.333 1.00 96.69 ? 212 HIS A CD2 1 
ATOM   1347 C  CE1 . HIS A 1 224 ? 81.137  120.503 106.016 1.00 96.69 ? 212 HIS A CE1 1 
ATOM   1348 N  NE2 . HIS A 1 224 ? 81.342  119.199 105.974 1.00 96.69 ? 212 HIS A NE2 1 
ATOM   1349 N  N   . PRO A 1 225 ? 87.913  121.453 105.925 1.00 95.40 ? 213 PRO A N   1 
ATOM   1350 C  CA  . PRO A 1 225 ? 89.260  121.351 106.484 1.00 95.40 ? 213 PRO A CA  1 
ATOM   1351 C  C   . PRO A 1 225 ? 89.242  121.780 107.939 1.00 95.40 ? 213 PRO A C   1 
ATOM   1352 O  O   . PRO A 1 225 ? 90.010  121.248 108.737 1.00 95.40 ? 213 PRO A O   1 
ATOM   1353 C  CB  . PRO A 1 225 ? 90.071  122.355 105.650 1.00 95.40 ? 213 PRO A CB  1 
ATOM   1354 C  CG  . PRO A 1 225 ? 89.187  122.756 104.509 1.00 95.40 ? 213 PRO A CG  1 
ATOM   1355 C  CD  . PRO A 1 225 ? 87.788  122.599 105.013 1.00 95.40 ? 213 PRO A CD  1 
ATOM   1356 N  N   . GLY A 1 226 ? 88.371  122.723 108.287 1.00 96.80 ? 214 GLY A N   1 
ATOM   1357 C  CA  . GLY A 1 226 ? 88.331  123.225 109.644 1.00 96.80 ? 214 GLY A CA  1 
ATOM   1358 C  C   . GLY A 1 226 ? 89.495  124.138 109.949 1.00 96.80 ? 214 GLY A C   1 
ATOM   1359 O  O   . GLY A 1 226 ? 90.198  124.576 109.044 1.00 96.80 ? 214 GLY A O   1 
ATOM   1360 N  N   . SER A 1 227 ? 89.704  124.433 111.225 1.00 97.35 ? 215 SER A N   1 
ATOM   1361 C  CA  . SER A 1 227 ? 90.796  125.305 111.616 1.00 97.35 ? 215 SER A CA  1 
ATOM   1362 C  C   . SER A 1 227 ? 92.081  124.529 111.813 1.00 97.35 ? 215 SER A C   1 
ATOM   1363 O  O   . SER A 1 227 ? 92.049  123.353 112.148 1.00 97.35 ? 215 SER A O   1 
ATOM   1364 C  CB  . SER A 1 227 ? 90.447  126.029 112.908 1.00 97.35 ? 215 SER A CB  1 
ATOM   1365 O  OG  . SER A 1 227 ? 90.452  125.137 114.007 1.00 97.35 ? 215 SER A OG  1 
ATOM   1366 N  N   . LEU A 1 228 ? 93.218  125.177 111.610 1.00 98.02 ? 216 LEU A N   1 
ATOM   1367 C  CA  . LEU A 1 228 ? 94.481  124.518 111.882 1.00 98.02 ? 216 LEU A CA  1 
ATOM   1368 C  C   . LEU A 1 228 ? 94.501  124.337 113.382 1.00 98.02 ? 216 LEU A C   1 
ATOM   1369 O  O   . LEU A 1 228 ? 94.282  125.291 114.122 1.00 98.02 ? 216 LEU A O   1 
ATOM   1370 C  CB  . LEU A 1 228 ? 95.647  125.395 111.450 1.00 98.02 ? 216 LEU A CB  1 
ATOM   1371 C  CG  . LEU A 1 228 ? 97.047  124.791 111.501 1.00 98.02 ? 216 LEU A CG  1 
ATOM   1372 C  CD1 . LEU A 1 228 ? 97.136  123.627 110.534 1.00 98.02 ? 216 LEU A CD1 1 
ATOM   1373 C  CD2 . LEU A 1 228 ? 98.077  125.849 111.147 1.00 98.02 ? 216 LEU A CD2 1 
ATOM   1374 N  N   . LYS A 1 229 ? 94.762  123.124 113.848 1.00 97.89 ? 217 LYS A N   1 
ATOM   1375 C  CA  . LYS A 1 229 ? 94.860  122.917 115.273 1.00 97.89 ? 217 LYS A CA  1 
ATOM   1376 C  C   . LYS A 1 229 ? 96.228  123.416 115.640 1.00 97.89 ? 217 LYS A C   1 
ATOM   1377 O  O   . LYS A 1 229 ? 97.227  122.875 115.181 1.00 97.89 ? 217 LYS A O   1 
ATOM   1378 C  CB  . LYS A 1 229 ? 94.737  121.440 115.591 1.00 97.89 ? 217 LYS A CB  1 
ATOM   1379 C  CG  . LYS A 1 229 ? 93.420  120.819 115.172 1.00 97.89 ? 217 LYS A CG  1 
ATOM   1380 C  CD  . LYS A 1 229 ? 92.571  120.551 116.395 1.00 97.89 ? 217 LYS A CD  1 
ATOM   1381 C  CE  . LYS A 1 229 ? 93.359  119.751 117.415 1.00 97.89 ? 217 LYS A CE  1 
ATOM   1382 N  NZ  . LYS A 1 229 ? 92.623  119.600 118.697 1.00 97.89 ? 217 LYS A NZ  1 
ATOM   1383 N  N   . TRP A 1 230 ? 96.290  124.466 116.447 1.00 97.91 ? 218 TRP A N   1 
ATOM   1384 C  CA  . TRP A 1 230 ? 97.571  125.071 116.784 1.00 97.91 ? 218 TRP A CA  1 
ATOM   1385 C  C   . TRP A 1 230 ? 98.458  124.140 117.580 1.00 97.91 ? 218 TRP A C   1 
ATOM   1386 O  O   . TRP A 1 230 ? 99.658  124.098 117.360 1.00 97.91 ? 218 TRP A O   1 
ATOM   1387 C  CB  . TRP A 1 230 ? 97.358  126.393 117.532 1.00 97.91 ? 218 TRP A CB  1 
ATOM   1388 C  CG  . TRP A 1 230 ? 96.711  126.245 118.877 1.00 97.91 ? 218 TRP A CG  1 
ATOM   1389 C  CD1 . TRP A 1 230 ? 95.378  126.136 119.140 1.00 97.91 ? 218 TRP A CD1 1 
ATOM   1390 C  CD2 . TRP A 1 230 ? 97.375  126.191 120.146 1.00 97.91 ? 218 TRP A CD2 1 
ATOM   1391 N  NE1 . TRP A 1 230 ? 95.171  126.011 120.492 1.00 97.91 ? 218 TRP A NE1 1 
ATOM   1392 C  CE2 . TRP A 1 230 ? 96.382  126.041 121.131 1.00 97.91 ? 218 TRP A CE2 1 
ATOM   1393 C  CE3 . TRP A 1 230 ? 98.714  126.247 120.542 1.00 97.91 ? 218 TRP A CE3 1 
ATOM   1394 C  CZ2 . TRP A 1 230 ? 96.684  125.952 122.485 1.00 97.91 ? 218 TRP A CZ2 1 
ATOM   1395 C  CZ3 . TRP A 1 230 ? 99.012  126.156 121.884 1.00 97.91 ? 218 TRP A CZ3 1 
ATOM   1396 C  CH2 . TRP A 1 230 ? 98.002  126.012 122.841 1.00 97.91 ? 218 TRP A CH2 1 
ATOM   1397 N  N   . ASP A 1 231 ? 97.867  123.376 118.486 1.00 97.79 ? 219 ASP A N   1 
ATOM   1398 C  CA  . ASP A 1 231 ? 98.647  122.496 119.338 1.00 97.79 ? 219 ASP A CA  1 
ATOM   1399 C  C   . ASP A 1 231 ? 99.328  121.377 118.566 1.00 97.79 ? 219 ASP A C   1 
ATOM   1400 O  O   . ASP A 1 231 ? 100.456 121.029 118.869 1.00 97.79 ? 219 ASP A O   1 
ATOM   1401 C  CB  . ASP A 1 231 ? 97.781  121.963 120.477 1.00 97.79 ? 219 ASP A CB  1 
ATOM   1402 C  CG  . ASP A 1 231 ? 96.367  121.648 120.044 1.00 97.79 ? 219 ASP A CG  1 
ATOM   1403 O  OD1 . ASP A 1 231 ? 96.176  121.094 118.943 1.00 97.79 ? 219 ASP A OD1 1 
ATOM   1404 O  OD2 . ASP A 1 231 ? 95.438  121.938 120.823 1.00 97.79 ? 219 ASP A OD2 1 
ATOM   1405 N  N   . LEU A 1 232 ? 98.659  120.828 117.560 1.00 98.34 ? 220 LEU A N   1 
ATOM   1406 C  CA  . LEU A 1 232 ? 99.261  119.790 116.737 1.00 98.34 ? 220 LEU A CA  1 
ATOM   1407 C  C   . LEU A 1 232 ? 100.232 120.393 115.748 1.00 98.34 ? 220 LEU A C   1 
ATOM   1408 O  O   . LEU A 1 232 ? 101.197 119.744 115.367 1.00 98.34 ? 220 LEU A O   1 
ATOM   1409 C  CB  . LEU A 1 232 ? 98.199  118.982 116.006 1.00 98.34 ? 220 LEU A CB  1 
ATOM   1410 C  CG  . LEU A 1 232 ? 97.471  117.887 116.776 1.00 98.34 ? 220 LEU A CG  1 
ATOM   1411 C  CD1 . LEU A 1 232 ? 96.561  117.148 115.811 1.00 98.34 ? 220 LEU A CD1 1 
ATOM   1412 C  CD2 . LEU A 1 232 ? 98.485  116.932 117.380 1.00 98.34 ? 220 LEU A CD2 1 
ATOM   1413 N  N   . ALA A 1 233 ? 99.980  121.620 115.311 1.00 98.67 ? 221 ALA A N   1 
ATOM   1414 C  CA  . ALA A 1 233 ? 100.922 122.306 114.430 1.00 98.67 ? 221 ALA A CA  1 
ATOM   1415 C  C   . ALA A 1 233 ? 102.236 122.600 115.127 1.00 98.67 ? 221 ALA A C   1 
ATOM   1416 O  O   . ALA A 1 233 ? 103.291 122.535 114.511 1.00 98.67 ? 221 ALA A O   1 
ATOM   1417 C  CB  . ALA A 1 233 ? 100.309 123.581 113.896 1.00 98.67 ? 221 ALA A CB  1 
ATOM   1418 N  N   . LEU A 1 234 ? 102.180 122.963 116.400 1.00 98.70 ? 222 LEU A N   1 
ATOM   1419 C  CA  . LEU A 1 234 ? 103.397 123.205 117.160 1.00 98.70 ? 222 LEU A CA  1 
ATOM   1420 C  C   . LEU A 1 234 ? 104.125 121.908 117.447 1.00 98.70 ? 222 LEU A C   1 
ATOM   1421 O  O   . LEU A 1 234 ? 105.347 121.886 117.464 1.00 98.70 ? 222 LEU A O   1 
ATOM   1422 C  CB  . LEU A 1 234 ? 103.082 123.932 118.460 1.00 98.70 ? 222 LEU A CB  1 
ATOM   1423 C  CG  . LEU A 1 234 ? 102.620 125.379 118.318 1.00 98.70 ? 222 LEU A CG  1 
ATOM   1424 C  CD1 . LEU A 1 234 ? 102.418 125.995 119.692 1.00 98.70 ? 222 LEU A CD1 1 
ATOM   1425 C  CD2 . LEU A 1 234 ? 103.632 126.177 117.512 1.00 98.70 ? 222 LEU A CD2 1 
ATOM   1426 N  N   . CYS A 1 235 ? 103.391 120.828 117.676 1.00 98.77 ? 223 CYS A N   1 
ATOM   1427 C  CA  . CYS A 1 235 ? 104.015 119.527 117.879 1.00 98.77 ? 223 CYS A CA  1 
ATOM   1428 C  C   . CYS A 1 235 ? 104.702 119.080 116.612 1.00 98.77 ? 223 CYS A C   1 
ATOM   1429 O  O   . CYS A 1 235 ? 105.792 118.545 116.670 1.00 98.77 ? 223 CYS A O   1 
ATOM   1430 C  CB  . CYS A 1 235 ? 102.993 118.494 118.341 1.00 98.77 ? 223 CYS A CB  1 
ATOM   1431 S  SG  . CYS A 1 235 ? 102.326 118.762 119.997 1.00 98.77 ? 223 CYS A SG  1 
ATOM   1432 N  N   . LEU A 1 236 ? 104.083 119.318 115.463 1.00 98.81 ? 224 LEU A N   1 
ATOM   1433 C  CA  . LEU A 1 236 ? 104.687 118.971 114.184 1.00 98.81 ? 224 LEU A CA  1 
ATOM   1434 C  C   . LEU A 1 236 ? 105.964 119.748 113.955 1.00 98.81 ? 224 LEU A C   1 
ATOM   1435 O  O   . LEU A 1 236 ? 106.941 119.200 113.461 1.00 98.81 ? 224 LEU A O   1 
ATOM   1436 C  CB  . LEU A 1 236 ? 103.702 119.239 113.051 1.00 98.81 ? 224 LEU A CB  1 
ATOM   1437 C  CG  . LEU A 1 236 ? 104.012 118.662 111.673 1.00 98.81 ? 224 LEU A CG  1 
ATOM   1438 C  CD1 . LEU A 1 236 ? 104.177 117.157 111.759 1.00 98.81 ? 224 LEU A CD1 1 
ATOM   1439 C  CD2 . LEU A 1 236 ? 102.907 119.026 110.699 1.00 98.81 ? 224 LEU A CD2 1 
ATOM   1440 N  N   . LEU A 1 237 ? 105.971 121.025 114.314 1.00 98.75 ? 225 LEU A N   1 
ATOM   1441 C  CA  . LEU A 1 237 ? 107.172 121.833 114.180 1.00 98.75 ? 225 LEU A CA  1 
ATOM   1442 C  C   . LEU A 1 237 ? 108.283 121.304 115.062 1.00 98.75 ? 225 LEU A C   1 
ATOM   1443 O  O   . LEU A 1 237 ? 109.433 121.255 114.647 1.00 98.75 ? 225 LEU A O   1 
ATOM   1444 C  CB  . LEU A 1 237 ? 106.883 123.286 114.527 1.00 98.75 ? 225 LEU A CB  1 
ATOM   1445 C  CG  . LEU A 1 237 ? 107.960 124.310 114.184 1.00 98.75 ? 225 LEU A CG  1 
ATOM   1446 C  CD1 . LEU A 1 237 ? 108.364 124.190 112.723 1.00 98.75 ? 225 LEU A CD1 1 
ATOM   1447 C  CD2 . LEU A 1 237 ? 107.453 125.707 114.492 1.00 98.75 ? 225 LEU A CD2 1 
ATOM   1448 N  N   . LEU A 1 238 ? 107.946 120.886 116.275 1.00 98.73 ? 226 LEU A N   1 
ATOM   1449 C  CA  . LEU A 1 238 ? 108.950 120.343 117.171 1.00 98.73 ? 226 LEU A CA  1 
ATOM   1450 C  C   . LEU A 1 238 ? 109.576 119.101 116.583 1.00 98.73 ? 226 LEU A C   1 
ATOM   1451 O  O   . LEU A 1 238 ? 110.785 118.925 116.662 1.00 98.73 ? 226 LEU A O   1 
ATOM   1452 C  CB  . LEU A 1 238 ? 108.346 120.018 118.528 1.00 98.73 ? 226 LEU A CB  1 
ATOM   1453 C  CG  . LEU A 1 238 ? 108.074 121.227 119.419 1.00 98.73 ? 226 LEU A CG  1 
ATOM   1454 C  CD1 . LEU A 1 238 ? 107.306 120.816 120.665 1.00 98.73 ? 226 LEU A CD1 1 
ATOM   1455 C  CD2 . LEU A 1 238 ? 109.383 121.911 119.782 1.00 98.73 ? 226 LEU A CD2 1 
ATOM   1456 N  N   . VAL A 1 239 ? 108.763 118.219 116.025 1.00 98.60 ? 227 VAL A N   1 
ATOM   1457 C  CA  . VAL A 1 239 ? 109.290 117.009 115.432 1.00 98.60 ? 227 VAL A CA  1 
ATOM   1458 C  C   . VAL A 1 239 ? 110.156 117.390 114.238 1.00 98.60 ? 227 VAL A C   1 
ATOM   1459 O  O   . VAL A 1 239 ? 111.242 116.853 114.071 1.00 98.60 ? 227 VAL A O   1 
ATOM   1460 C  CB  . VAL A 1 239 ? 108.172 116.013 115.083 1.00 98.60 ? 227 VAL A CB  1 
ATOM   1461 C  CG1 . VAL A 1 239 ? 108.773 114.677 114.706 1.00 98.60 ? 227 VAL A CG1 1 
ATOM   1462 C  CG2 . VAL A 1 239 ? 107.272 115.802 116.285 1.00 98.60 ? 227 VAL A CG2 1 
ATOM   1463 N  N   . TRP A 1 240 ? 109.702 118.330 113.420 1.00 98.53 ? 228 TRP A N   1 
ATOM   1464 C  CA  . TRP A 1 240 ? 110.507 118.811 112.295 1.00 98.53 ? 228 TRP A CA  1 
ATOM   1465 C  C   . TRP A 1 240 ? 111.787 119.523 112.698 1.00 98.53 ? 228 TRP A C   1 
ATOM   1466 O  O   . TRP A 1 240 ? 112.798 119.387 112.026 1.00 98.53 ? 228 TRP A O   1 
ATOM   1467 C  CB  . TRP A 1 240 ? 109.688 119.683 111.349 1.00 98.53 ? 228 TRP A CB  1 
ATOM   1468 C  CG  . TRP A 1 240 ? 108.944 118.898 110.329 1.00 98.53 ? 228 TRP A CG  1 
ATOM   1469 C  CD1 . TRP A 1 240 ? 107.595 118.788 110.209 1.00 98.53 ? 228 TRP A CD1 1 
ATOM   1470 C  CD2 . TRP A 1 240 ? 109.507 118.096 109.284 1.00 98.53 ? 228 TRP A CD2 1 
ATOM   1471 N  NE1 . TRP A 1 240 ? 107.279 117.976 109.152 1.00 98.53 ? 228 TRP A NE1 1 
ATOM   1472 C  CE2 . TRP A 1 240 ? 108.437 117.536 108.568 1.00 98.53 ? 228 TRP A CE2 1 
ATOM   1473 C  CE3 . TRP A 1 240 ? 110.814 117.797 108.886 1.00 98.53 ? 228 TRP A CE3 1 
ATOM   1474 C  CZ2 . TRP A 1 240 ? 108.630 116.693 107.479 1.00 98.53 ? 228 TRP A CZ2 1 
ATOM   1475 C  CZ3 . TRP A 1 240 ? 111.002 116.963 107.806 1.00 98.53 ? 228 TRP A CZ3 1 
ATOM   1476 C  CH2 . TRP A 1 240 ? 109.918 116.421 107.114 1.00 98.53 ? 228 TRP A CH2 1 
ATOM   1477 N  N   . LEU A 1 241 ? 111.742 120.317 113.762 1.00 98.33 ? 229 LEU A N   1 
ATOM   1478 C  CA  . LEU A 1 241 ? 112.940 120.984 114.255 1.00 98.33 ? 229 LEU A CA  1 
ATOM   1479 C  C   . LEU A 1 241 ? 113.969 119.976 114.720 1.00 98.33 ? 229 LEU A C   1 
ATOM   1480 O  O   . LEU A 1 241 ? 115.149 120.128 114.440 1.00 98.33 ? 229 LEU A O   1 
ATOM   1481 C  CB  . LEU A 1 241 ? 112.602 121.936 115.398 1.00 98.33 ? 229 LEU A CB  1 
ATOM   1482 C  CG  . LEU A 1 241 ? 112.011 123.289 115.012 1.00 98.33 ? 229 LEU A CG  1 
ATOM   1483 C  CD1 . LEU A 1 241 ? 111.636 124.080 116.254 1.00 98.33 ? 229 LEU A CD1 1 
ATOM   1484 C  CD2 . LEU A 1 241 ? 112.982 124.068 114.141 1.00 98.33 ? 229 LEU A CD2 1 
ATOM   1485 N  N   . VAL A 1 242 ? 113.533 118.933 115.413 1.00 97.68 ? 230 VAL A N   1 
ATOM   1486 C  CA  . VAL A 1 242 ? 114.455 117.892 115.832 1.00 97.68 ? 230 VAL A CA  1 
ATOM   1487 C  C   . VAL A 1 242 ? 115.041 117.241 114.592 1.00 97.68 ? 230 VAL A C   1 
ATOM   1488 O  O   . VAL A 1 242 ? 116.244 117.011 114.521 1.00 97.68 ? 230 VAL A O   1 
ATOM   1489 C  CB  . VAL A 1 242 ? 113.764 116.837 116.718 1.00 97.68 ? 230 VAL A CB  1 
ATOM   1490 C  CG1 . VAL A 1 242 ? 114.650 115.620 116.920 1.00 97.68 ? 230 VAL A CG1 1 
ATOM   1491 C  CG2 . VAL A 1 242 ? 113.382 117.440 118.058 1.00 97.68 ? 230 VAL A CG2 1 
ATOM   1492 N  N   . CYS A 1 243 ? 114.206 116.993 113.589 1.00 97.47 ? 231 CYS A N   1 
ATOM   1493 C  CA  . CYS A 1 243 ? 114.691 116.351 112.388 1.00 97.47 ? 231 CYS A CA  1 
ATOM   1494 C  C   . CYS A 1 243 ? 115.739 117.205 111.711 1.00 97.47 ? 231 CYS A C   1 
ATOM   1495 O  O   . CYS A 1 243 ? 116.796 116.710 111.353 1.00 97.47 ? 231 CYS A O   1 
ATOM   1496 C  CB  . CYS A 1 243 ? 113.549 116.070 111.407 1.00 97.47 ? 231 CYS A CB  1 
ATOM   1497 S  SG  . CYS A 1 243 ? 112.518 114.642 111.797 1.00 97.47 ? 231 CYS A SG  1 
ATOM   1498 N  N   . PHE A 1 244 ? 115.479 118.500 111.584 1.00 97.02 ? 232 PHE A N   1 
ATOM   1499 C  CA  . PHE A 1 244 ? 116.428 119.365 110.912 1.00 97.02 ? 232 PHE A CA  1 
ATOM   1500 C  C   . PHE A 1 244 ? 117.733 119.419 111.672 1.00 97.02 ? 232 PHE A C   1 
ATOM   1501 O  O   . PHE A 1 244 ? 118.799 119.296 111.085 1.00 97.02 ? 232 PHE A O   1 
ATOM   1502 C  CB  . PHE A 1 244 ? 115.879 120.783 110.772 1.00 97.02 ? 232 PHE A CB  1 
ATOM   1503 C  CG  . PHE A 1 244 ? 116.915 121.792 110.357 1.00 97.02 ? 232 PHE A CG  1 
ATOM   1504 C  CD1 . PHE A 1 244 ? 117.388 121.821 109.056 1.00 97.02 ? 232 PHE A CD1 1 
ATOM   1505 C  CD2 . PHE A 1 244 ? 117.420 122.706 111.268 1.00 97.02 ? 232 PHE A CD2 1 
ATOM   1506 C  CE1 . PHE A 1 244 ? 118.344 122.739 108.673 1.00 97.02 ? 232 PHE A CE1 1 
ATOM   1507 C  CE2 . PHE A 1 244 ? 118.377 123.625 110.891 1.00 97.02 ? 232 PHE A CE2 1 
ATOM   1508 C  CZ  . PHE A 1 244 ? 118.838 123.643 109.591 1.00 97.02 ? 232 PHE A CZ  1 
ATOM   1509 N  N   . PHE A 1 245 ? 117.658 119.579 112.984 1.00 95.43 ? 233 PHE A N   1 
ATOM   1510 C  CA  . PHE A 1 245 ? 118.878 119.707 113.752 1.00 95.43 ? 233 PHE A CA  1 
ATOM   1511 C  C   . PHE A 1 245 ? 119.733 118.459 113.730 1.00 95.43 ? 233 PHE A C   1 
ATOM   1512 O  O   . PHE A 1 245 ? 120.940 118.542 113.566 1.00 95.43 ? 233 PHE A O   1 
ATOM   1513 C  CB  . PHE A 1 245 ? 118.598 120.200 115.163 1.00 95.43 ? 233 PHE A CB  1 
ATOM   1514 C  CG  . PHE A 1 245 ? 118.463 121.691 115.250 1.00 95.43 ? 233 PHE A CG  1 
ATOM   1515 C  CD1 . PHE A 1 245 ? 119.578 122.501 115.148 1.00 95.43 ? 233 PHE A CD1 1 
ATOM   1516 C  CD2 . PHE A 1 245 ? 117.224 122.285 115.399 1.00 95.43 ? 233 PHE A CD2 1 
ATOM   1517 C  CE1 . PHE A 1 245 ? 119.465 123.875 115.211 1.00 95.43 ? 233 PHE A CE1 1 
ATOM   1518 C  CE2 . PHE A 1 245 ? 117.100 123.659 115.463 1.00 95.43 ? 233 PHE A CE2 1 
ATOM   1519 C  CZ  . PHE A 1 245 ? 118.223 124.455 115.369 1.00 95.43 ? 233 PHE A CZ  1 
ATOM   1520 N  N   . CYS A 1 246 ? 119.118 117.297 113.866 1.00 94.93 ? 234 CYS A N   1 
ATOM   1521 C  CA  . CYS A 1 246 ? 119.877 116.064 113.773 1.00 94.93 ? 234 CYS A CA  1 
ATOM   1522 C  C   . CYS A 1 246 ? 120.476 115.844 112.386 1.00 94.93 ? 234 CYS A C   1 
ATOM   1523 O  O   . CYS A 1 246 ? 121.622 115.435 112.265 1.00 94.93 ? 234 CYS A O   1 
ATOM   1524 C  CB  . CYS A 1 246 ? 119.006 114.885 114.183 1.00 94.93 ? 234 CYS A CB  1 
ATOM   1525 S  SG  . CYS A 1 246 ? 118.485 114.954 115.910 1.00 94.93 ? 234 CYS A SG  1 
ATOM   1526 N  N   . ILE A 1 247 ? 119.739 116.169 111.335 1.00 94.65 ? 235 ILE A N   1 
ATOM   1527 C  CA  . ILE A 1 247 ? 120.285 116.045 109.991 1.00 94.65 ? 235 ILE A CA  1 
ATOM   1528 C  C   . ILE A 1 247 ? 121.371 117.085 109.737 1.00 94.65 ? 235 ILE A C   1 
ATOM   1529 O  O   . ILE A 1 247 ? 122.449 116.754 109.249 1.00 94.65 ? 235 ILE A O   1 
ATOM   1530 C  CB  . ILE A 1 247 ? 119.173 116.121 108.933 1.00 94.65 ? 235 ILE A CB  1 
ATOM   1531 C  CG1 . ILE A 1 247 ? 118.195 114.968 109.136 1.00 94.65 ? 235 ILE A CG1 1 
ATOM   1532 C  CG2 . ILE A 1 247 ? 119.746 116.059 107.527 1.00 94.65 ? 235 ILE A CG2 1 
ATOM   1533 C  CD1 . ILE A 1 247 ? 116.922 115.113 108.344 1.00 94.65 ? 235 ILE A CD1 1 
ATOM   1534 N  N   . TRP A 1 248 ? 121.099 118.339 110.067 1.00 93.13 ? 236 TRP A N   1 
ATOM   1535 C  CA  . TRP A 1 248 ? 122.077 119.403 109.859 1.00 93.13 ? 236 TRP A CA  1 
ATOM   1536 C  C   . TRP A 1 248 ? 123.342 119.240 110.683 1.00 93.13 ? 236 TRP A C   1 
ATOM   1537 O  O   . TRP A 1 248 ? 124.443 119.420 110.166 1.00 93.13 ? 236 TRP A O   1 
ATOM   1538 C  CB  . TRP A 1 248 ? 121.436 120.756 110.149 1.00 93.13 ? 236 TRP A CB  1 
ATOM   1539 C  CG  . TRP A 1 248 ? 122.389 121.892 110.199 1.00 93.13 ? 236 TRP A CG  1 
ATOM   1540 C  CD1 . TRP A 1 248 ? 123.108 122.406 109.163 1.00 93.13 ? 236 TRP A CD1 1 
ATOM   1541 C  CD2 . TRP A 1 248 ? 122.720 122.675 111.346 1.00 93.13 ? 236 TRP A CD2 1 
ATOM   1542 N  NE1 . TRP A 1 248 ? 123.876 123.456 109.597 1.00 93.13 ? 236 TRP A NE1 1 
ATOM   1543 C  CE2 . TRP A 1 248 ? 123.654 123.642 110.936 1.00 93.13 ? 236 TRP A CE2 1 
ATOM   1544 C  CE3 . TRP A 1 248 ? 122.320 122.648 112.683 1.00 93.13 ? 236 TRP A CE3 1 
ATOM   1545 C  CZ2 . TRP A 1 248 ? 124.194 124.576 111.814 1.00 93.13 ? 236 TRP A CZ2 1 
ATOM   1546 C  CZ3 . TRP A 1 248 ? 122.855 123.576 113.552 1.00 93.13 ? 236 TRP A CZ3 1 
ATOM   1547 C  CH2 . TRP A 1 248 ? 123.783 124.526 113.116 1.00 93.13 ? 236 TRP A CH2 1 
ATOM   1548 N  N   . LYS A 1 249 ? 123.203 118.897 111.956 1.00 90.74 ? 237 LYS A N   1 
ATOM   1549 C  CA  . LYS A 1 249 ? 124.377 118.644 112.782 1.00 90.74 ? 237 LYS A CA  1 
ATOM   1550 C  C   . LYS A 1 249 ? 125.101 117.430 112.256 1.00 90.74 ? 237 LYS A C   1 
ATOM   1551 O  O   . LYS A 1 249 ? 126.330 117.390 112.241 1.00 90.74 ? 237 LYS A O   1 
ATOM   1552 C  CB  . LYS A 1 249 ? 124.018 118.468 114.251 1.00 90.74 ? 237 LYS A CB  1 
ATOM   1553 C  CG  . LYS A 1 249 ? 123.835 119.773 115.002 1.00 90.74 ? 237 LYS A CG  1 
ATOM   1554 C  CD  . LYS A 1 249 ? 125.106 120.603 114.949 1.00 90.74 ? 237 LYS A CD  1 
ATOM   1555 C  CE  . LYS A 1 249 ? 125.032 121.784 115.902 1.00 90.74 ? 237 LYS A CE  1 
ATOM   1556 N  NZ  . LYS A 1 249 ? 124.843 121.344 117.312 1.00 90.74 ? 237 LYS A NZ  1 
ATOM   1557 N  N   . GLY A 1 250 ? 124.342 116.432 111.830 1.00 89.91 ? 238 GLY A N   1 
ATOM   1558 C  CA  . GLY A 1 250 ? 124.944 115.238 111.278 1.00 89.91 ? 238 GLY A CA  1 
ATOM   1559 C  C   . GLY A 1 250 ? 125.050 114.230 112.383 1.00 89.91 ? 238 GLY A C   1 
ATOM   1560 O  O   . GLY A 1 250 ? 125.966 113.409 112.397 1.00 89.91 ? 238 GLY A O   1 
ATOM   1561 N  N   . VAL A 1 251 ? 124.119 114.302 113.324 1.00 90.14 ? 239 VAL A N   1 
ATOM   1562 C  CA  . VAL A 1 251 ? 124.131 113.379 114.437 1.00 90.14 ? 239 VAL A CA  1 
ATOM   1563 C  C   . VAL A 1 251 ? 123.526 112.125 113.860 1.00 90.14 ? 239 VAL A C   1 
ATOM   1564 O  O   . VAL A 1 251 ? 122.310 111.999 113.810 1.00 90.14 ? 239 VAL A O   1 
ATOM   1565 C  CB  . VAL A 1 251 ? 123.230 113.871 115.577 1.00 90.14 ? 239 VAL A CB  1 
ATOM   1566 C  CG1 . VAL A 1 251 ? 123.381 112.976 116.797 1.00 90.14 ? 239 VAL A CG1 1 
ATOM   1567 C  CG2 . VAL A 1 251 ? 123.564 115.310 115.930 1.00 90.14 ? 239 VAL A CG2 1 
ATOM   1568 N  N   . ARG A 1 252 ? 124.366 111.238 113.340 1.00 86.21 ? 240 ARG A N   1 
ATOM   1569 C  CA  . ARG A 1 252 ? 123.883 109.981 112.788 1.00 86.21 ? 240 ARG A CA  1 
ATOM   1570 C  C   . ARG A 1 252 ? 124.501 108.790 113.515 1.00 86.21 ? 240 ARG A C   1 
ATOM   1571 O  O   . ARG A 1 252 ? 124.008 107.666 113.423 1.00 86.21 ? 240 ARG A O   1 
ATOM   1572 C  CB  . ARG A 1 252 ? 124.168 109.920 111.282 1.00 86.21 ? 240 ARG A CB  1 
ATOM   1573 C  CG  . ARG A 1 252 ? 123.441 108.815 110.523 1.00 86.21 ? 240 ARG A CG  1 
ATOM   1574 C  CD  . ARG A 1 252 ? 121.938 108.842 110.761 1.00 86.21 ? 240 ARG A CD  1 
ATOM   1575 N  NE  . ARG A 1 252 ? 121.507 107.880 111.772 1.00 86.21 ? 240 ARG A NE  1 
ATOM   1576 C  CZ  . ARG A 1 252 ? 120.252 107.747 112.188 1.00 86.21 ? 240 ARG A CZ  1 
ATOM   1577 N  NH1 . ARG A 1 252 ? 119.302 108.516 111.678 1.00 86.21 ? 240 ARG A NH1 1 
ATOM   1578 N  NH2 . ARG A 1 252 ? 119.947 106.847 113.113 1.00 86.21 ? 240 ARG A NH2 1 
ATOM   1579 N  N   . SER A 1 253 ? 125.577 109.028 114.255 1.00 88.90 ? 241 SER A N   1 
ATOM   1580 C  CA  . SER A 1 253 ? 126.242 107.941 114.967 1.00 88.90 ? 241 SER A CA  1 
ATOM   1581 C  C   . SER A 1 253 ? 126.037 107.996 116.476 1.00 88.90 ? 241 SER A C   1 
ATOM   1582 O  O   . SER A 1 253 ? 126.426 108.968 117.123 1.00 88.90 ? 241 SER A O   1 
ATOM   1583 C  CB  . SER A 1 253 ? 127.736 107.926 114.643 1.00 88.90 ? 241 SER A CB  1 
ATOM   1584 O  OG  . SER A 1 253 ? 128.347 109.156 114.992 1.00 88.90 ? 241 SER A OG  1 
ATOM   1585 N  N   . THR A 1 254 ? 125.424 106.958 117.041 1.00 90.11 ? 242 THR A N   1 
ATOM   1586 C  CA  . THR A 1 254 ? 125.235 106.894 118.486 1.00 90.11 ? 242 THR A CA  1 
ATOM   1587 C  C   . THR A 1 254 ? 125.682 105.530 118.967 1.00 90.11 ? 242 THR A C   1 
ATOM   1588 O  O   . THR A 1 254 ? 124.862 104.737 119.414 1.00 90.11 ? 242 THR A O   1 
ATOM   1589 C  CB  . THR A 1 254 ? 123.757 107.097 118.868 1.00 90.11 ? 242 THR A CB  1 
ATOM   1590 O  OG1 . THR A 1 254 ? 122.923 106.423 117.918 1.00 90.11 ? 242 THR A OG1 1 
ATOM   1591 C  CG2 . THR A 1 254 ? 123.398 108.574 118.880 1.00 90.11 ? 242 THR A CG2 1 
ATOM   1592 N  N   . GLY A 1 255 ? 126.981 105.260 118.926 1.00 89.65 ? 243 GLY A N   1 
ATOM   1593 C  CA  . GLY A 1 255 ? 127.490 103.954 119.319 1.00 89.65 ? 243 GLY A CA  1 
ATOM   1594 C  C   . GLY A 1 255 ? 127.215 103.495 120.740 1.00 89.65 ? 243 GLY A C   1 
ATOM   1595 O  O   . GLY A 1 255 ? 126.886 102.336 120.968 1.00 89.65 ? 243 GLY A O   1 
ATOM   1596 N  N   . LYS A 1 256 ? 127.329 104.393 121.709 1.00 91.64 ? 244 LYS A N   1 
ATOM   1597 C  CA  . LYS A 1 256 ? 127.142 104.002 123.106 1.00 91.64 ? 244 LYS A CA  1 
ATOM   1598 C  C   . LYS A 1 256 ? 125.691 103.697 123.471 1.00 91.64 ? 244 LYS A C   1 
ATOM   1599 O  O   . LYS A 1 256 ? 125.429 102.769 124.233 1.00 91.64 ? 244 LYS A O   1 
ATOM   1600 C  CB  . LYS A 1 256 ? 127.705 105.081 124.035 1.00 91.64 ? 244 LYS A CB  1 
ATOM   1601 C  CG  . LYS A 1 256 ? 127.192 106.483 123.745 1.00 91.64 ? 244 LYS A CG  1 
ATOM   1602 C  CD  . LYS A 1 256 ? 127.678 107.480 124.782 1.00 91.64 ? 244 LYS A CD  1 
ATOM   1603 C  CE  . LYS A 1 256 ? 127.070 108.853 124.544 1.00 91.64 ? 244 LYS A CE  1 
ATOM   1604 N  NZ  . LYS A 1 256 ? 127.404 109.381 123.193 1.00 91.64 ? 244 LYS A NZ  1 
ATOM   1605 N  N   . VAL A 1 257 ? 124.752 104.473 122.937 1.00 93.46 ? 245 VAL A N   1 
ATOM   1606 C  CA  . VAL A 1 257 ? 123.346 104.302 123.309 1.00 93.46 ? 245 VAL A CA  1 
ATOM   1607 C  C   . VAL A 1 257 ? 122.489 103.653 122.235 1.00 93.46 ? 245 VAL A C   1 
ATOM   1608 O  O   . VAL A 1 257 ? 121.265 103.654 122.341 1.00 93.46 ? 245 VAL A O   1 
ATOM   1609 C  CB  . VAL A 1 257 ? 122.708 105.646 123.711 1.00 93.46 ? 245 VAL A CB  1 
ATOM   1610 C  CG1 . VAL A 1 257 ? 123.199 106.079 125.084 1.00 93.46 ? 245 VAL A CG1 1 
ATOM   1611 C  CG2 . VAL A 1 257 ? 123.011 106.710 122.668 1.00 93.46 ? 245 VAL A CG2 1 
ATOM   1612 N  N   . VAL A 1 258 ? 123.117 103.083 121.212 1.00 94.70 ? 246 VAL A N   1 
ATOM   1613 C  CA  . VAL A 1 258 ? 122.350 102.372 120.193 1.00 94.70 ? 246 VAL A CA  1 
ATOM   1614 C  C   . VAL A 1 258 ? 121.655 101.200 120.870 1.00 94.70 ? 246 VAL A C   1 
ATOM   1615 O  O   . VAL A 1 258 ? 120.516 100.876 120.544 1.00 94.70 ? 246 VAL A O   1 
ATOM   1616 C  CB  . VAL A 1 258 ? 123.214 101.931 118.984 1.00 94.70 ? 246 VAL A CB  1 
ATOM   1617 C  CG1 . VAL A 1 258 ? 124.312 100.959 119.389 1.00 94.70 ? 246 VAL A CG1 1 
ATOM   1618 C  CG2 . VAL A 1 258 ? 122.348 101.348 117.878 1.00 94.70 ? 246 VAL A CG2 1 
ATOM   1619 N  N   . TYR A 1 259 ? 122.337 100.566 121.817 1.00 95.23 ? 247 TYR A N   1 
ATOM   1620 C  CA  . TYR A 1 259 ? 121.755 99.445  122.537 1.00 95.23 ? 247 TYR A CA  1 
ATOM   1621 C  C   . TYR A 1 259 ? 120.457 99.834  123.241 1.00 95.23 ? 247 TYR A C   1 
ATOM   1622 O  O   . TYR A 1 259 ? 119.460 99.138  123.106 1.00 95.23 ? 247 TYR A O   1 
ATOM   1623 C  CB  . TYR A 1 259 ? 122.768 98.885  123.532 1.00 95.23 ? 247 TYR A CB  1 
ATOM   1624 C  CG  . TYR A 1 259 ? 124.137 98.690  122.923 1.00 95.23 ? 247 TYR A CG  1 
ATOM   1625 C  CD1 . TYR A 1 259 ? 124.372 97.672  122.008 1.00 95.23 ? 247 TYR A CD1 1 
ATOM   1626 C  CD2 . TYR A 1 259 ? 125.192 99.530  123.253 1.00 95.23 ? 247 TYR A CD2 1 
ATOM   1627 C  CE1 . TYR A 1 259 ? 125.620 97.493  121.443 1.00 95.23 ? 247 TYR A CE1 1 
ATOM   1628 C  CE2 . TYR A 1 259 ? 126.443 99.358  122.694 1.00 95.23 ? 247 TYR A CE2 1 
ATOM   1629 C  CZ  . TYR A 1 259 ? 126.651 98.339  121.790 1.00 95.23 ? 247 TYR A CZ  1 
ATOM   1630 O  OH  . TYR A 1 259 ? 127.896 98.164  121.231 1.00 95.23 ? 247 TYR A OH  1 
ATOM   1631 N  N   . PHE A 1 260 ? 120.460 100.943 123.980 1.00 94.33 ? 248 PHE A N   1 
ATOM   1632 C  CA  . PHE A 1 260 ? 119.235 101.398 124.635 1.00 94.33 ? 248 PHE A CA  1 
ATOM   1633 C  C   . PHE A 1 260 ? 118.147 101.656 123.607 1.00 94.33 ? 248 PHE A C   1 
ATOM   1634 O  O   . PHE A 1 260 ? 117.004 101.281 123.808 1.00 94.33 ? 248 PHE A O   1 
ATOM   1635 C  CB  . PHE A 1 260 ? 119.483 102.660 125.462 1.00 94.33 ? 248 PHE A CB  1 
ATOM   1636 C  CG  . PHE A 1 260 ? 118.225 103.337 125.932 1.00 94.33 ? 248 PHE A CG  1 
ATOM   1637 C  CD1 . PHE A 1 260 ? 117.485 102.805 126.974 1.00 94.33 ? 248 PHE A CD1 1 
ATOM   1638 C  CD2 . PHE A 1 260 ? 117.785 104.508 125.334 1.00 94.33 ? 248 PHE A CD2 1 
ATOM   1639 C  CE1 . PHE A 1 260 ? 116.328 103.424 127.406 1.00 94.33 ? 248 PHE A CE1 1 
ATOM   1640 C  CE2 . PHE A 1 260 ? 116.629 105.129 125.760 1.00 94.33 ? 248 PHE A CE2 1 
ATOM   1641 C  CZ  . PHE A 1 260 ? 115.900 104.588 126.799 1.00 94.33 ? 248 PHE A CZ  1 
ATOM   1642 N  N   . THR A 1 261 ? 118.505 102.276 122.494 1.00 95.12 ? 249 THR A N   1 
ATOM   1643 C  CA  . THR A 1 261 ? 117.534 102.565 121.447 1.00 95.12 ? 249 THR A CA  1 
ATOM   1644 C  C   . THR A 1 261 ? 116.955 101.287 120.848 1.00 95.12 ? 249 THR A C   1 
ATOM   1645 O  O   . THR A 1 261 ? 115.796 101.261 120.463 1.00 95.12 ? 249 THR A O   1 
ATOM   1646 C  CB  . THR A 1 261 ? 118.120 103.478 120.362 1.00 95.12 ? 249 THR A CB  1 
ATOM   1647 O  OG1 . THR A 1 261 ? 119.004 104.428 120.969 1.00 95.12 ? 249 THR A OG1 1 
ATOM   1648 C  CG2 . THR A 1 261 ? 117.013 104.225 119.646 1.00 95.12 ? 249 THR A CG2 1 
ATOM   1649 N  N   . ALA A 1 262 ? 117.765 100.244 120.713 1.00 94.25 ? 250 ALA A N   1 
ATOM   1650 C  CA  . ALA A 1 262 ? 117.266 98.965  120.216 1.00 94.25 ? 250 ALA A CA  1 
ATOM   1651 C  C   . ALA A 1 262 ? 116.444 98.244  121.277 1.00 94.25 ? 250 ALA A C   1 
ATOM   1652 O  O   . ALA A 1 262 ? 115.310 97.852  121.021 1.00 94.25 ? 250 ALA A O   1 
ATOM   1653 C  CB  . ALA A 1 262 ? 118.416 98.089  119.759 1.00 94.25 ? 250 ALA A CB  1 
ATOM   1654 N  N   . THR A 1 263 ? 117.010 98.065  122.465 1.00 94.12 ? 251 THR A N   1 
ATOM   1655 C  CA  . THR A 1 263 ? 116.293 97.398  123.548 1.00 94.12 ? 251 THR A CA  1 
ATOM   1656 C  C   . THR A 1 263 ? 115.021 98.052  124.050 1.00 94.12 ? 251 THR A C   1 
ATOM   1657 O  O   . THR A 1 263 ? 114.065 97.357  124.364 1.00 94.12 ? 251 THR A O   1 
ATOM   1658 C  CB  . THR A 1 263 ? 117.204 97.106  124.752 1.00 94.12 ? 251 THR A CB  1 
ATOM   1659 O  OG1 . THR A 1 263 ? 117.767 98.330  125.236 1.00 94.12 ? 251 THR A OG1 1 
ATOM   1660 C  CG2 . THR A 1 263 ? 118.316 96.150  124.359 1.00 94.12 ? 251 THR A CG2 1 
ATOM   1661 N  N   . PHE A 1 264 ? 114.995 99.369  124.179 1.00 93.43 ? 252 PHE A N   1 
ATOM   1662 C  CA  . PHE A 1 264 ? 113.824 100.033 124.763 1.00 93.43 ? 252 PHE A CA  1 
ATOM   1663 C  C   . PHE A 1 264 ? 112.469 99.677  124.121 1.00 93.43 ? 252 PHE A C   1 
ATOM   1664 O  O   . PHE A 1 264 ? 111.529 99.344  124.834 1.00 93.43 ? 252 PHE A O   1 
ATOM   1665 C  CB  . PHE A 1 264 ? 114.047 101.547 124.861 1.00 93.43 ? 252 PHE A CB  1 
ATOM   1666 C  CG  . PHE A 1 264 ? 112.924 102.286 125.514 1.00 93.43 ? 252 PHE A CG  1 
ATOM   1667 C  CD1 . PHE A 1 264 ? 112.570 102.016 126.822 1.00 93.43 ? 252 PHE A CD1 1 
ATOM   1668 C  CD2 . PHE A 1 264 ? 112.233 103.264 124.825 1.00 93.43 ? 252 PHE A CD2 1 
ATOM   1669 C  CE1 . PHE A 1 264 ? 111.535 102.697 127.426 1.00 93.43 ? 252 PHE A CE1 1 
ATOM   1670 C  CE2 . PHE A 1 264 ? 111.201 103.951 125.424 1.00 93.43 ? 252 PHE A CE2 1 
ATOM   1671 C  CZ  . PHE A 1 264 ? 110.851 103.667 126.724 1.00 93.43 ? 252 PHE A CZ  1 
ATOM   1672 N  N   . PRO A 1 265 ? 112.365 99.715  122.785 1.00 93.22 ? 253 PRO A N   1 
ATOM   1673 C  CA  . PRO A 1 265 ? 111.078 99.326  122.216 1.00 93.22 ? 253 PRO A CA  1 
ATOM   1674 C  C   . PRO A 1 265 ? 110.659 97.897  122.513 1.00 93.22 ? 253 PRO A C   1 
ATOM   1675 O  O   . PRO A 1 265 ? 109.498 97.668  122.816 1.00 93.22 ? 253 PRO A O   1 
ATOM   1676 C  CB  . PRO A 1 265 ? 111.325 99.468  120.720 1.00 93.22 ? 253 PRO A CB  1 
ATOM   1677 C  CG  . PRO A 1 265 ? 112.272 100.599 120.626 1.00 93.22 ? 253 PRO A CG  1 
ATOM   1678 C  CD  . PRO A 1 265 ? 113.185 100.431 121.797 1.00 93.22 ? 253 PRO A CD  1 
ATOM   1679 N  N   . PHE A 1 266 ? 111.580 96.953  122.429 1.00 93.24 ? 254 PHE A N   1 
ATOM   1680 C  CA  . PHE A 1 266 ? 111.258 95.568  122.718 1.00 93.24 ? 254 PHE A CA  1 
ATOM   1681 C  C   . PHE A 1 266 ? 110.838 95.360  124.162 1.00 93.24 ? 254 PHE A C   1 
ATOM   1682 O  O   . PHE A 1 266 ? 109.911 94.607  124.430 1.00 93.24 ? 254 PHE A O   1 
ATOM   1683 C  CB  . PHE A 1 266 ? 112.414 94.655  122.332 1.00 93.24 ? 254 PHE A CB  1 
ATOM   1684 C  CG  . PHE A 1 266 ? 112.592 94.517  120.852 1.00 93.24 ? 254 PHE A CG  1 
ATOM   1685 C  CD1 . PHE A 1 266 ? 111.637 93.870  120.088 1.00 93.24 ? 254 PHE A CD1 1 
ATOM   1686 C  CD2 . PHE A 1 266 ? 113.705 95.040  120.222 1.00 93.24 ? 254 PHE A CD2 1 
ATOM   1687 C  CE1 . PHE A 1 266 ? 111.791 93.744  118.722 1.00 93.24 ? 254 PHE A CE1 1 
ATOM   1688 C  CE2 . PHE A 1 266 ? 113.866 94.917  118.857 1.00 93.24 ? 254 PHE A CE2 1 
ATOM   1689 C  CZ  . PHE A 1 266 ? 112.908 94.267  118.105 1.00 93.24 ? 254 PHE A CZ  1 
ATOM   1690 N  N   . ALA A 1 267 ? 111.511 96.023  125.093 1.00 93.38 ? 255 ALA A N   1 
ATOM   1691 C  CA  . ALA A 1 267 ? 111.124 95.929  126.490 1.00 93.38 ? 255 ALA A CA  1 
ATOM   1692 C  C   . ALA A 1 267 ? 109.736 96.496  126.715 1.00 93.38 ? 255 ALA A C   1 
ATOM   1693 O  O   . ALA A 1 267 ? 108.941 95.910  127.439 1.00 93.38 ? 255 ALA A O   1 
ATOM   1694 C  CB  . ALA A 1 267 ? 112.130 96.653  127.355 1.00 93.38 ? 255 ALA A CB  1 
ATOM   1695 N  N   . MET A 1 268 ? 109.434 97.629  126.092 1.00 91.00 ? 256 MET A N   1 
ATOM   1696 C  CA  . MET A 1 268 ? 108.101 98.209  126.210 1.00 91.00 ? 256 MET A CA  1 
ATOM   1697 C  C   . MET A 1 268 ? 107.042 97.313  125.604 1.00 91.00 ? 256 MET A C   1 
ATOM   1698 O  O   . MET A 1 268 ? 105.978 97.128  126.182 1.00 91.00 ? 256 MET A O   1 
ATOM   1699 C  CB  . MET A 1 268 ? 108.047 99.593  125.557 1.00 91.00 ? 256 MET A CB  1 
ATOM   1700 C  CG  . MET A 1 268 ? 108.237 100.743 126.525 1.00 91.00 ? 256 MET A CG  1 
ATOM   1701 S  SD  . MET A 1 268 ? 107.073 100.670 127.898 1.00 91.00 ? 256 MET A SD  1 
ATOM   1702 C  CE  . MET A 1 268 ? 105.504 100.856 127.059 1.00 91.00 ? 256 MET A CE  1 
ATOM   1703 N  N   . LEU A 1 269 ? 107.337 96.739  124.447 1.00 92.25 ? 257 LEU A N   1 
ATOM   1704 C  CA  . LEU A 1 269 ? 106.390 95.852  123.792 1.00 92.25 ? 257 LEU A CA  1 
ATOM   1705 C  C   . LEU A 1 269 ? 106.120 94.626  124.629 1.00 92.25 ? 257 LEU A C   1 
ATOM   1706 O  O   . LEU A 1 269 ? 104.995 94.156  124.678 1.00 92.25 ? 257 LEU A O   1 
ATOM   1707 C  CB  . LEU A 1 269 ? 106.860 95.475  122.391 1.00 92.25 ? 257 LEU A CB  1 
ATOM   1708 C  CG  . LEU A 1 269 ? 106.622 96.541  121.320 1.00 92.25 ? 257 LEU A CG  1 
ATOM   1709 C  CD1 . LEU A 1 269 ? 107.329 96.180  120.024 1.00 92.25 ? 257 LEU A CD1 1 
ATOM   1710 C  CD2 . LEU A 1 269 ? 105.133 96.746  121.090 1.00 92.25 ? 257 LEU A CD2 1 
ATOM   1711 N  N   . LEU A 1 270 ? 107.146 94.098  125.282 1.00 94.10 ? 258 LEU A N   1 
ATOM   1712 C  CA  . LEU A 1 270 ? 106.961 92.948  126.151 1.00 94.10 ? 258 LEU A CA  1 
ATOM   1713 C  C   . LEU A 1 270 ? 106.030 93.270  127.308 1.00 94.10 ? 258 LEU A C   1 
ATOM   1714 O  O   . LEU A 1 270 ? 105.160 92.474  127.639 1.00 94.10 ? 258 LEU A O   1 
ATOM   1715 C  CB  . LEU A 1 270 ? 108.305 92.469  126.683 1.00 94.10 ? 258 LEU A CB  1 
ATOM   1716 C  CG  . LEU A 1 270 ? 108.312 91.279  127.640 1.00 94.10 ? 258 LEU A CG  1 
ATOM   1717 C  CD1 . LEU A 1 270 ? 107.862 90.017  126.921 1.00 94.10 ? 258 LEU A CD1 1 
ATOM   1718 C  CD2 . LEU A 1 270 ? 109.698 91.092  128.233 1.00 94.10 ? 258 LEU A CD2 1 
ATOM   1719 N  N   . VAL A 1 271 ? 106.183 94.441  127.912 1.00 91.86 ? 259 VAL A N   1 
ATOM   1720 C  CA  . VAL A 1 271 ? 105.288 94.837  128.991 1.00 91.86 ? 259 VAL A CA  1 
ATOM   1721 C  C   . VAL A 1 271 ? 103.860 94.974  128.490 1.00 91.86 ? 259 VAL A C   1 
ATOM   1722 O  O   . VAL A 1 271 ? 102.924 94.517  129.140 1.00 91.86 ? 259 VAL A O   1 
ATOM   1723 C  CB  . VAL A 1 271 ? 105.748 96.154  129.643 1.00 91.86 ? 259 VAL A CB  1 
ATOM   1724 C  CG1 . VAL A 1 271 ? 104.846 96.520  130.807 1.00 91.86 ? 259 VAL A CG1 1 
ATOM   1725 C  CG2 . VAL A 1 271 ? 107.180 96.024  130.133 1.00 91.86 ? 259 VAL A CG2 1 
ATOM   1726 N  N   . LEU A 1 272 ? 103.685 95.578  127.320 1.00 88.86 ? 260 LEU A N   1 
ATOM   1727 C  CA  . LEU A 1 272 ? 102.354 95.716  126.738 1.00 88.86 ? 260 LEU A CA  1 
ATOM   1728 C  C   . LEU A 1 272 ? 101.752 94.359  126.420 1.00 88.86 ? 260 LEU A C   1 
ATOM   1729 O  O   . LEU A 1 272 ? 100.566 94.139  126.644 1.00 88.86 ? 260 LEU A O   1 
ATOM   1730 C  CB  . LEU A 1 272 ? 102.415 96.566  125.473 1.00 88.86 ? 260 LEU A CB  1 
ATOM   1731 C  CG  . LEU A 1 272 ? 102.692 98.061  125.626 1.00 88.86 ? 260 LEU A CG  1 
ATOM   1732 C  CD1 . LEU A 1 272 ? 103.243 98.641  124.334 1.00 88.86 ? 260 LEU A CD1 1 
ATOM   1733 C  CD2 . LEU A 1 272 ? 101.442 98.803  126.066 1.00 88.86 ? 260 LEU A CD2 1 
ATOM   1734 N  N   . LEU A 1 273 ? 102.563 93.448  125.893 1.00 93.72 ? 261 LEU A N   1 
ATOM   1735 C  CA  . LEU A 1 273 ? 102.085 92.114  125.572 1.00 93.72 ? 261 LEU A CA  1 
ATOM   1736 C  C   . LEU A 1 273 ? 101.635 91.367  126.809 1.00 93.72 ? 261 LEU A C   1 
ATOM   1737 O  O   . LEU A 1 273 ? 100.570 90.774  126.809 1.00 93.72 ? 261 LEU A O   1 
ATOM   1738 C  CB  . LEU A 1 273 ? 103.188 91.326  124.876 1.00 93.72 ? 261 LEU A CB  1 
ATOM   1739 C  CG  . LEU A 1 273 ? 102.939 89.873  124.478 1.00 93.72 ? 261 LEU A CG  1 
ATOM   1740 C  CD1 . LEU A 1 273 ? 101.932 89.794  123.344 1.00 93.72 ? 261 LEU A CD1 1 
ATOM   1741 C  CD2 . LEU A 1 273 ? 104.249 89.221  124.068 1.00 93.72 ? 261 LEU A CD2 1 
ATOM   1742 N  N   . VAL A 1 274 ? 102.418 91.428  127.881 1.00 95.35 ? 262 VAL A N   1 
ATOM   1743 C  CA  . VAL A 1 274 ? 102.054 90.747  129.115 1.00 95.35 ? 262 VAL A CA  1 
ATOM   1744 C  C   . VAL A 1 274 ? 100.779 91.335  129.698 1.00 95.35 ? 262 VAL A C   1 
ATOM   1745 O  O   . VAL A 1 274 ? 99.897  90.603  130.132 1.00 95.35 ? 262 VAL A O   1 
ATOM   1746 C  CB  . VAL A 1 274 ? 103.203 90.765  130.136 1.00 95.35 ? 262 VAL A CB  1 
ATOM   1747 C  CG1 . VAL A 1 274 ? 102.748 90.236  131.487 1.00 95.35 ? 262 VAL A CG1 1 
ATOM   1748 C  CG2 . VAL A 1 274 ? 104.375 89.948  129.618 1.00 95.35 ? 262 VAL A CG2 1 
ATOM   1749 N  N   . ARG A 1 275 ? 100.658 92.656  129.673 1.00 89.46 ? 263 ARG A N   1 
ATOM   1750 C  CA  . ARG A 1 275 ? 99.442  93.296  130.153 1.00 89.46 ? 263 ARG A CA  1 
ATOM   1751 C  C   . ARG A 1 275 ? 98.231  92.777  129.396 1.00 89.46 ? 263 ARG A C   1 
ATOM   1752 O  O   . ARG A 1 275 ? 97.239  92.407  130.005 1.00 89.46 ? 263 ARG A O   1 
ATOM   1753 C  CB  . ARG A 1 275 ? 99.540  94.820  130.036 1.00 89.46 ? 263 ARG A CB  1 
ATOM   1754 C  CG  . ARG A 1 275 ? 98.267  95.590  130.365 1.00 89.46 ? 263 ARG A CG  1 
ATOM   1755 C  CD  . ARG A 1 275 ? 97.956  95.604  131.854 1.00 89.46 ? 263 ARG A CD  1 
ATOM   1756 N  NE  . ARG A 1 275 ? 97.261  94.400  132.298 1.00 89.46 ? 263 ARG A NE  1 
ATOM   1757 C  CZ  . ARG A 1 275 ? 96.876  94.178  133.548 1.00 89.46 ? 263 ARG A CZ  1 
ATOM   1758 N  NH1 . ARG A 1 275 ? 97.114  95.082  134.487 1.00 89.46 ? 263 ARG A NH1 1 
ATOM   1759 N  NH2 . ARG A 1 275 ? 96.251  93.052  133.859 1.00 89.46 ? 263 ARG A NH2 1 
ATOM   1760 N  N   . GLY A 1 276 ? 98.303  92.742  128.070 1.00 91.47 ? 264 GLY A N   1 
ATOM   1761 C  CA  . GLY A 1 276 ? 97.161  92.311  127.290 1.00 91.47 ? 264 GLY A CA  1 
ATOM   1762 C  C   . GLY A 1 276 ? 96.778  90.878  127.564 1.00 91.47 ? 264 GLY A C   1 
ATOM   1763 O  O   . GLY A 1 276 ? 95.597  90.576  127.774 1.00 91.47 ? 264 GLY A O   1 
ATOM   1764 N  N   . LEU A 1 277 ? 97.764  89.988  127.537 1.00 95.69 ? 265 LEU A N   1 
ATOM   1765 C  CA  . LEU A 1 277 ? 97.505  88.565  127.739 1.00 95.69 ? 265 LEU A CA  1 
ATOM   1766 C  C   . LEU A 1 277 ? 96.901  88.277  129.097 1.00 95.69 ? 265 LEU A C   1 
ATOM   1767 O  O   . LEU A 1 277 ? 96.173  87.302  129.260 1.00 95.69 ? 265 LEU A O   1 
ATOM   1768 C  CB  . LEU A 1 277 ? 98.789  87.756  127.565 1.00 95.69 ? 265 LEU A CB  1 
ATOM   1769 C  CG  . LEU A 1 277 ? 99.497  87.835  126.214 1.00 95.69 ? 265 LEU A CG  1 
ATOM   1770 C  CD1 . LEU A 1 277 ? 100.762 86.994  126.221 1.00 95.69 ? 265 LEU A CD1 1 
ATOM   1771 C  CD2 . LEU A 1 277 ? 98.577  87.424  125.080 1.00 95.69 ? 265 LEU A CD2 1 
ATOM   1772 N  N   . THR A 1 278 ? 97.188  89.127  130.072 1.00 94.52 ? 266 THR A N   1 
ATOM   1773 C  CA  . THR A 1 278 ? 96.636  88.943  131.404 1.00 94.52 ? 266 THR A CA  1 
ATOM   1774 C  C   . THR A 1 278 ? 95.296  89.642  131.522 1.00 94.52 ? 266 THR A C   1 
ATOM   1775 O  O   . THR A 1 278 ? 94.673  89.622  132.580 1.00 94.52 ? 266 THR A O   1 
ATOM   1776 C  CB  . THR A 1 278 ? 97.585  89.453  132.494 1.00 94.52 ? 266 THR A CB  1 
ATOM   1777 O  OG1 . THR A 1 278 ? 97.930  90.817  132.233 1.00 94.52 ? 266 THR A OG1 1 
ATOM   1778 C  CG2 . THR A 1 278 ? 98.849  88.612  132.532 1.00 94.52 ? 266 THR A CG2 1 
ATOM   1779 N  N   . LEU A 1 279 ? 94.856  90.274  130.442 1.00 91.74 ? 267 LEU A N   1 
ATOM   1780 C  CA  . LEU A 1 279 ? 93.599  91.004  130.464 1.00 91.74 ? 267 LEU A CA  1 
ATOM   1781 C  C   . LEU A 1 279 ? 92.384  90.123  130.084 1.00 91.74 ? 267 LEU A C   1 
ATOM   1782 O  O   . LEU A 1 279 ? 92.429  89.458  129.058 1.00 91.74 ? 267 LEU A O   1 
ATOM   1783 C  CB  . LEU A 1 279 ? 93.683  92.236  129.564 1.00 91.74 ? 267 LEU A CB  1 
ATOM   1784 C  CG  . LEU A 1 279 ? 94.653  93.354  129.933 1.00 91.74 ? 267 LEU A CG  1 
ATOM   1785 C  CD1 . LEU A 1 279 ? 94.726  94.435  128.872 1.00 91.74 ? 267 LEU A CD1 1 
ATOM   1786 C  CD2 . LEU A 1 279 ? 94.323  93.930  131.300 1.00 91.74 ? 267 LEU A CD2 1 
ATOM   1787 N  N   . PRO A 1 280 ? 91.297  90.100  130.908 1.00 92.79 ? 268 PRO A N   1 
ATOM   1788 C  CA  . PRO A 1 280 ? 90.107  89.338  130.509 1.00 92.79 ? 268 PRO A CA  1 
ATOM   1789 C  C   . PRO A 1 280 ? 89.582  89.691  129.118 1.00 92.79 ? 268 PRO A C   1 
ATOM   1790 O  O   . PRO A 1 280 ? 89.275  90.845  128.876 1.00 92.79 ? 268 PRO A O   1 
ATOM   1791 C  CB  . PRO A 1 280 ? 89.071  89.706  131.579 1.00 92.79 ? 268 PRO A CB  1 
ATOM   1792 C  CG  . PRO A 1 280 ? 89.651  90.845  132.350 1.00 92.79 ? 268 PRO A CG  1 
ATOM   1793 C  CD  . PRO A 1 280 ? 91.135  90.717  132.232 1.00 92.79 ? 268 PRO A CD  1 
ATOM   1794 N  N   . GLY A 1 281 ? 89.471  88.716  128.225 1.00 92.84 ? 269 GLY A N   1 
ATOM   1795 C  CA  . GLY A 1 281 ? 88.977  88.948  126.884 1.00 92.84 ? 269 GLY A CA  1 
ATOM   1796 C  C   . GLY A 1 281 ? 90.111  88.859  125.892 1.00 92.84 ? 269 GLY A C   1 
ATOM   1797 O  O   . GLY A 1 281 ? 89.908  89.038  124.699 1.00 92.84 ? 269 GLY A O   1 
ATOM   1798 N  N   . ALA A 1 282 ? 91.308  88.558  126.375 1.00 94.76 ? 270 ALA A N   1 
ATOM   1799 C  CA  . ALA A 1 282 ? 92.463  88.458  125.507 1.00 94.76 ? 270 ALA A CA  1 
ATOM   1800 C  C   . ALA A 1 282 ? 92.303  87.346  124.511 1.00 94.76 ? 270 ALA A C   1 
ATOM   1801 O  O   . ALA A 1 282 ? 92.665  87.503  123.353 1.00 94.76 ? 270 ALA A O   1 
ATOM   1802 C  CB  . ALA A 1 282 ? 93.707  88.226  126.329 1.00 94.76 ? 270 ALA A CB  1 
ATOM   1803 N  N   . GLY A 1 283 ? 91.753  86.217  124.945 1.00 95.31 ? 271 GLY A N   1 
ATOM   1804 C  CA  . GLY A 1 283 ? 91.623  85.067  124.071 1.00 95.31 ? 271 GLY A CA  1 
ATOM   1805 C  C   . GLY A 1 283 ? 90.757  85.324  122.869 1.00 95.31 ? 271 GLY A C   1 
ATOM   1806 O  O   . GLY A 1 283 ? 91.081  84.878  121.778 1.00 95.31 ? 271 GLY A O   1 
ATOM   1807 N  N   . ALA A 1 284 ? 89.657  86.037  123.055 1.00 94.19 ? 272 ALA A N   1 
ATOM   1808 C  CA  . ALA A 1 284 ? 88.796  86.380  121.938 1.00 94.19 ? 272 ALA A CA  1 
ATOM   1809 C  C   . ALA A 1 284 ? 89.526  87.258  120.942 1.00 94.19 ? 272 ALA A C   1 
ATOM   1810 O  O   . ALA A 1 284 ? 89.376  87.080  119.741 1.00 94.19 ? 272 ALA A O   1 
ATOM   1811 C  CB  . ALA A 1 284 ? 87.550  87.077  122.442 1.00 94.19 ? 272 ALA A CB  1 
ATOM   1812 N  N   . GLY A 1 285 ? 90.302  88.217  121.426 1.00 94.24 ? 273 GLY A N   1 
ATOM   1813 C  CA  . GLY A 1 285 ? 91.080  89.063  120.545 1.00 94.24 ? 273 GLY A CA  1 
ATOM   1814 C  C   . GLY A 1 285 ? 92.125  88.290  119.796 1.00 94.24 ? 273 GLY A C   1 
ATOM   1815 O  O   . GLY A 1 285 ? 92.340  88.530  118.619 1.00 94.24 ? 273 GLY A O   1 
ATOM   1816 N  N   . ILE A 1 286 ? 92.792  87.368  120.473 1.00 96.39 ? 274 ILE A N   1 
ATOM   1817 C  CA  . ILE A 1 286 ? 93.789  86.528  119.826 1.00 96.39 ? 274 ILE A CA  1 
ATOM   1818 C  C   . ILE A 1 286 ? 93.136  85.653  118.767 1.00 96.39 ? 274 ILE A C   1 
ATOM   1819 O  O   . ILE A 1 286 ? 93.683  85.478  117.689 1.00 96.39 ? 274 ILE A O   1 
ATOM   1820 C  CB  . ILE A 1 286 ? 94.542  85.681  120.866 1.00 96.39 ? 274 ILE A CB  1 
ATOM   1821 C  CG1 . ILE A 1 286 ? 95.437  86.576  121.720 1.00 96.39 ? 274 ILE A CG1 1 
ATOM   1822 C  CG2 . ILE A 1 286 ? 95.372  84.593  120.207 1.00 96.39 ? 274 ILE A CG2 1 
ATOM   1823 C  CD1 . ILE A 1 286 ? 96.052  85.860  122.898 1.00 96.39 ? 274 ILE A CD1 1 
ATOM   1824 N  N   . LYS A 1 287 ? 91.961  85.109  119.057 1.00 95.98 ? 275 LYS A N   1 
ATOM   1825 C  CA  . LYS A 1 287 ? 91.241  84.314  118.072 1.00 95.98 ? 275 LYS A CA  1 
ATOM   1826 C  C   . LYS A 1 287 ? 90.834  85.148  116.873 1.00 95.98 ? 275 LYS A C   1 
ATOM   1827 O  O   . LYS A 1 287 ? 90.965  84.711  115.750 1.00 95.98 ? 275 LYS A O   1 
ATOM   1828 C  CB  . LYS A 1 287 ? 90.018  83.663  118.710 1.00 95.98 ? 275 LYS A CB  1 
ATOM   1829 C  CG  . LYS A 1 287 ? 89.124  82.908  117.743 1.00 95.98 ? 275 LYS A CG  1 
ATOM   1830 C  CD  . LYS A 1 287 ? 88.012  82.178  118.474 1.00 95.98 ? 275 LYS A CD  1 
ATOM   1831 C  CE  . LYS A 1 287 ? 88.577  81.164  119.455 1.00 95.98 ? 275 LYS A CE  1 
ATOM   1832 N  NZ  . LYS A 1 287 ? 87.497  80.416  120.158 1.00 95.98 ? 275 LYS A NZ  1 
ATOM   1833 N  N   . PHE A 1 288 ? 90.326  86.348  117.106 1.00 93.21 ? 276 PHE A N   1 
ATOM   1834 C  CA  . PHE A 1 288 ? 89.961  87.243  116.018 1.00 93.21 ? 276 PHE A CA  1 
ATOM   1835 C  C   . PHE A 1 288 ? 91.188  87.448  115.162 1.00 93.21 ? 276 PHE A C   1 
ATOM   1836 O  O   . PHE A 1 288 ? 91.127  87.325  113.943 1.00 93.21 ? 276 PHE A O   1 
ATOM   1837 C  CB  . PHE A 1 288 ? 89.475  88.561  116.614 1.00 93.21 ? 276 PHE A CB  1 
ATOM   1838 C  CG  . PHE A 1 288 ? 89.068  89.596  115.608 1.00 93.21 ? 276 PHE A CG  1 
ATOM   1839 C  CD1 . PHE A 1 288 ? 87.898  89.460  114.885 1.00 93.21 ? 276 PHE A CD1 1 
ATOM   1840 C  CD2 . PHE A 1 288 ? 89.829  90.738  115.430 1.00 93.21 ? 276 PHE A CD2 1 
ATOM   1841 C  CE1 . PHE A 1 288 ? 87.515  90.426  113.974 1.00 93.21 ? 276 PHE A CE1 1 
ATOM   1842 C  CE2 . PHE A 1 288 ? 89.451  91.708  114.525 1.00 93.21 ? 276 PHE A CE2 1 
ATOM   1843 C  CZ  . PHE A 1 288 ? 88.293  91.552  113.795 1.00 93.21 ? 276 PHE A CZ  1 
ATOM   1844 N  N   . TYR A 1 289 ? 92.306  87.765  115.794 1.00 94.75 ? 277 TYR A N   1 
ATOM   1845 C  CA  . TYR A 1 289 ? 93.545  87.977  115.074 1.00 94.75 ? 277 TYR A CA  1 
ATOM   1846 C  C   . TYR A 1 289 ? 94.085  86.749  114.361 1.00 94.75 ? 277 TYR A C   1 
ATOM   1847 O  O   . TYR A 1 289 ? 94.482  86.827  113.208 1.00 94.75 ? 277 TYR A O   1 
ATOM   1848 C  CB  . TYR A 1 289 ? 94.560  88.427  116.118 1.00 94.75 ? 277 TYR A CB  1 
ATOM   1849 C  CG  . TYR A 1 289 ? 95.949  88.730  115.642 1.00 94.75 ? 277 TYR A CG  1 
ATOM   1850 C  CD1 . TYR A 1 289 ? 96.173  89.665  114.649 1.00 94.75 ? 277 TYR A CD1 1 
ATOM   1851 C  CD2 . TYR A 1 289 ? 97.045  88.118  116.228 1.00 94.75 ? 277 TYR A CD2 1 
ATOM   1852 C  CE1 . TYR A 1 289 ? 97.449  89.958  114.229 1.00 94.75 ? 277 TYR A CE1 1 
ATOM   1853 C  CE2 . TYR A 1 289 ? 98.324  88.405  115.812 1.00 94.75 ? 277 TYR A CE2 1 
ATOM   1854 C  CZ  . TYR A 1 289 ? 98.514  89.327  114.812 1.00 94.75 ? 277 TYR A CZ  1 
ATOM   1855 O  OH  . TYR A 1 289 ? 99.776  89.629  114.389 1.00 94.75 ? 277 TYR A OH  1 
ATOM   1856 N  N   . LEU A 1 290 ? 94.141  85.620  115.053 1.00 96.26 ? 278 LEU A N   1 
ATOM   1857 C  CA  . LEU A 1 290 ? 94.647  84.381  114.464 1.00 96.26 ? 278 LEU A CA  1 
ATOM   1858 C  C   . LEU A 1 290 ? 93.796  83.647  113.446 1.00 96.26 ? 278 LEU A C   1 
ATOM   1859 O  O   . LEU A 1 290 ? 94.317  83.170  112.443 1.00 96.26 ? 278 LEU A O   1 
ATOM   1860 C  CB  . LEU A 1 290 ? 95.131  83.421  115.550 1.00 96.26 ? 278 LEU A CB  1 
ATOM   1861 C  CG  . LEU A 1 290 ? 96.412  83.833  116.268 1.00 96.26 ? 278 LEU A CG  1 
ATOM   1862 C  CD1 . LEU A 1 290 ? 96.891  82.684  117.138 1.00 96.26 ? 278 LEU A CD1 1 
ATOM   1863 C  CD2 . LEU A 1 290 ? 97.480  84.218  115.257 1.00 96.26 ? 278 LEU A CD2 1 
ATOM   1864 N  N   . TYR A 1 291 ? 92.504  83.503  113.715 1.00 95.15 ? 279 TYR A N   1 
ATOM   1865 C  CA  . TYR A 1 291 ? 91.627  82.719  112.837 1.00 95.15 ? 279 TYR A CA  1 
ATOM   1866 C  C   . TYR A 1 291 ? 91.178  83.430  111.576 1.00 95.15 ? 279 TYR A C   1 
ATOM   1867 O  O   . TYR A 1 291 ? 90.521  84.464  111.650 1.00 95.15 ? 279 TYR A O   1 
ATOM   1868 C  CB  . TYR A 1 291 ? 90.409  82.224  113.612 1.00 95.15 ? 279 TYR A CB  1 
ATOM   1869 C  CG  . TYR A 1 291 ? 90.689  81.050  114.523 1.00 95.15 ? 279 TYR A CG  1 
ATOM   1870 C  CD1 . TYR A 1 291 ? 91.557  81.167  115.601 1.00 95.15 ? 279 TYR A CD1 1 
ATOM   1871 C  CD2 . TYR A 1 291 ? 90.075  79.826  114.310 1.00 95.15 ? 279 TYR A CD2 1 
ATOM   1872 C  CE1 . TYR A 1 291 ? 91.812  80.098  116.435 1.00 95.15 ? 279 TYR A CE1 1 
ATOM   1873 C  CE2 . TYR A 1 291 ? 90.323  78.750  115.140 1.00 95.15 ? 279 TYR A CE2 1 
ATOM   1874 C  CZ  . TYR A 1 291 ? 91.191  78.892  116.200 1.00 95.15 ? 279 TYR A CZ  1 
ATOM   1875 O  OH  . TYR A 1 291 ? 91.439  77.822  117.028 1.00 95.15 ? 279 TYR A OH  1 
ATOM   1876 N  N   . PRO A 1 292 ? 91.519  82.874  110.409 1.00 93.64 ? 280 PRO A N   1 
ATOM   1877 C  CA  . PRO A 1 292 ? 91.181  83.502  109.128 1.00 93.64 ? 280 PRO A CA  1 
ATOM   1878 C  C   . PRO A 1 292 ? 89.733  83.458  108.704 1.00 93.64 ? 280 PRO A C   1 
ATOM   1879 O  O   . PRO A 1 292 ? 89.038  82.501  109.031 1.00 93.64 ? 280 PRO A O   1 
ATOM   1880 C  CB  . PRO A 1 292 ? 91.998  82.686  108.120 1.00 93.64 ? 280 PRO A CB  1 
ATOM   1881 C  CG  . PRO A 1 292 ? 92.993  81.915  108.922 1.00 93.64 ? 280 PRO A CG  1 
ATOM   1882 C  CD  . PRO A 1 292 ? 92.311  81.651  110.224 1.00 93.64 ? 280 PRO A CD  1 
ATOM   1883 N  N   . ASP A 1 293 ? 89.270  84.479  107.987 1.00 92.55 ? 281 ASP A N   1 
ATOM   1884 C  CA  . ASP A 1 293 ? 87.915  84.473  107.440 1.00 92.55 ? 281 ASP A CA  1 
ATOM   1885 C  C   . ASP A 1 293 ? 88.121  84.476  105.941 1.00 92.55 ? 281 ASP A C   1 
ATOM   1886 O  O   . ASP A 1 293 ? 88.566  85.472  105.382 1.00 92.55 ? 281 ASP A O   1 
ATOM   1887 C  CB  . ASP A 1 293 ? 87.129  85.702  107.873 1.00 92.55 ? 281 ASP A CB  1 
ATOM   1888 C  CG  . ASP A 1 293 ? 85.684  85.662  107.416 1.00 92.55 ? 281 ASP A CG  1 
ATOM   1889 O  OD1 . ASP A 1 293 ? 85.179  84.562  107.108 1.00 92.55 ? 281 ASP A OD1 1 
ATOM   1890 O  OD2 . ASP A 1 293 ? 85.046  86.734  107.374 1.00 92.55 ? 281 ASP A OD2 1 
ATOM   1891 N  N   . ILE A 1 294 ? 87.800  83.373  105.278 1.00 95.07 ? 282 ILE A N   1 
ATOM   1892 C  CA  . ILE A 1 294 ? 88.068  83.253  103.845 1.00 95.07 ? 282 ILE A CA  1 
ATOM   1893 C  C   . ILE A 1 294 ? 87.325  84.262  102.971 1.00 95.07 ? 282 ILE A C   1 
ATOM   1894 O  O   . ILE A 1 294 ? 87.874  84.764  101.999 1.00 95.07 ? 282 ILE A O   1 
ATOM   1895 C  CB  . ILE A 1 294 ? 87.800  81.812  103.368 1.00 95.07 ? 282 ILE A CB  1 
ATOM   1896 C  CG1 . ILE A 1 294 ? 88.486  80.814  104.301 1.00 95.07 ? 282 ILE A CG1 1 
ATOM   1897 C  CG2 . ILE A 1 294 ? 88.285  81.607  101.941 1.00 95.07 ? 282 ILE A CG2 1 
ATOM   1898 C  CD1 . ILE A 1 294 ? 89.996  80.916  104.302 1.00 95.07 ? 282 ILE A CD1 1 
ATOM   1899 N  N   . THR A 1 295 ? 86.078  84.552  103.311 1.00 95.78 ? 283 THR A N   1 
ATOM   1900 C  CA  . THR A 1 295 ? 85.285  85.473  102.511 1.00 95.78 ? 283 THR A CA  1 
ATOM   1901 C  C   . THR A 1 295 ? 86.018  86.777  102.280 1.00 95.78 ? 283 THR A C   1 
ATOM   1902 O  O   . THR A 1 295 ? 85.862  87.401  101.238 1.00 95.78 ? 283 THR A O   1 
ATOM   1903 C  CB  . THR A 1 295 ? 83.938  85.760  103.186 1.00 95.78 ? 283 THR A CB  1 
ATOM   1904 O  OG1 . THR A 1 295 ? 84.154  86.485  104.402 1.00 95.78 ? 283 THR A OG1 1 
ATOM   1905 C  CG2 . THR A 1 295 ? 83.218  84.460  103.498 1.00 95.78 ? 283 THR A CG2 1 
ATOM   1906 N  N   . ARG A 1 296 ? 86.811  87.201  103.253 1.00 92.88 ? 284 ARG A N   1 
ATOM   1907 C  CA  . ARG A 1 296 ? 87.584  88.426  103.116 1.00 92.88 ? 284 ARG A CA  1 
ATOM   1908 C  C   . ARG A 1 296 ? 88.615  88.348  102.006 1.00 92.88 ? 284 ARG A C   1 
ATOM   1909 O  O   . ARG A 1 296 ? 88.857  89.328  101.324 1.00 92.88 ? 284 ARG A O   1 
ATOM   1910 C  CB  . ARG A 1 296 ? 88.255  88.776  104.435 1.00 92.88 ? 284 ARG A CB  1 
ATOM   1911 C  CG  . ARG A 1 296 ? 87.570  89.883  105.212 1.00 92.88 ? 284 ARG A CG  1 
ATOM   1912 C  CD  . ARG A 1 296 ? 87.808  91.221  104.538 1.00 92.88 ? 284 ARG A CD  1 
ATOM   1913 N  NE  . ARG A 1 296 ? 87.313  92.342  105.325 1.00 92.88 ? 284 ARG A NE  1 
ATOM   1914 C  CZ  . ARG A 1 296 ? 87.509  93.616  105.005 1.00 92.88 ? 284 ARG A CZ  1 
ATOM   1915 N  NH1 . ARG A 1 296 ? 88.200  93.930  103.917 1.00 92.88 ? 284 ARG A NH1 1 
ATOM   1916 N  NH2 . ARG A 1 296 ? 87.021  94.577  105.776 1.00 92.88 ? 284 ARG A NH2 1 
ATOM   1917 N  N   . LEU A 1 297 ? 89.254  87.199  101.848 1.00 93.46 ? 285 LEU A N   1 
ATOM   1918 C  CA  . LEU A 1 297 ? 90.270  87.037  100.817 1.00 93.46 ? 285 LEU A CA  1 
ATOM   1919 C  C   . LEU A 1 297 ? 89.706  87.267  99.425  1.00 93.46 ? 285 LEU A C   1 
ATOM   1920 O  O   . LEU A 1 297 ? 90.450  87.557  98.493  1.00 93.46 ? 285 LEU A O   1 
ATOM   1921 C  CB  . LEU A 1 297 ? 90.895  85.651  100.898 1.00 93.46 ? 285 LEU A CB  1 
ATOM   1922 C  CG  . LEU A 1 297 ? 91.503  85.274  102.243 1.00 93.46 ? 285 LEU A CG  1 
ATOM   1923 C  CD1 . LEU A 1 297 ? 92.033  83.852  102.192 1.00 93.46 ? 285 LEU A CD1 1 
ATOM   1924 C  CD2 . LEU A 1 297 ? 92.612  86.251  102.584 1.00 93.46 ? 285 LEU A CD2 1 
ATOM   1925 N  N   . GLU A 1 298 ? 88.395  87.131  99.275  1.00 92.63 ? 286 GLU A N   1 
ATOM   1926 C  CA  . GLU A 1 298 ? 87.769  87.385  97.983  1.00 92.63 ? 286 GLU A CA  1 
ATOM   1927 C  C   . GLU A 1 298 ? 87.685  88.877  97.703  1.00 92.63 ? 286 GLU A C   1 
ATOM   1928 O  O   . GLU A 1 298 ? 87.130  89.287  96.690  1.00 92.63 ? 286 GLU A O   1 
ATOM   1929 C  CB  . GLU A 1 298 ? 86.383  86.756  97.945  1.00 92.63 ? 286 GLU A CB  1 
ATOM   1930 C  CG  . GLU A 1 298 ? 86.374  85.280  98.304  1.00 92.63 ? 286 GLU A CG  1 
ATOM   1931 C  CD  . GLU A 1 298 ? 85.008  84.799  98.748  1.00 92.63 ? 286 GLU A CD  1 
ATOM   1932 O  OE1 . GLU A 1 298 ? 84.889  83.617  99.132  1.00 92.63 ? 286 GLU A OE1 1 
ATOM   1933 O  OE2 . GLU A 1 298 ? 84.055  85.605  98.722  1.00 92.63 ? 286 GLU A OE2 1 
ATOM   1934 N  N   . ASP A 1 299 ? 88.237  89.692  98.593  1.00 88.90 ? 287 ASP A N   1 
ATOM   1935 C  CA  . ASP A 1 299 ? 88.231  91.137  98.405  1.00 88.90 ? 287 ASP A CA  1 
ATOM   1936 C  C   . ASP A 1 299 ? 89.638  91.585  98.081  1.00 88.90 ? 287 ASP A C   1 
ATOM   1937 O  O   . ASP A 1 299 ? 90.583  91.195  98.761  1.00 88.90 ? 287 ASP A O   1 
ATOM   1938 C  CB  . ASP A 1 299 ? 87.752  91.854  99.665  1.00 88.90 ? 287 ASP A CB  1 
ATOM   1939 C  CG  . ASP A 1 299 ? 86.375  91.400  100.114 1.00 88.90 ? 287 ASP A CG  1 
ATOM   1940 O  OD1 . ASP A 1 299 ? 85.615  90.863  99.281  1.00 88.90 ? 287 ASP A OD1 1 
ATOM   1941 O  OD2 . ASP A 1 299 ? 86.048  91.592  101.305 1.00 88.90 ? 287 ASP A OD2 1 
ATOM   1942 N  N   . PRO A 1 300 ? 89.792  92.418  97.051  1.00 85.37 ? 288 PRO A N   1 
ATOM   1943 C  CA  . PRO A 1 300 ? 91.119  92.870  96.621  1.00 85.37 ? 288 PRO A CA  1 
ATOM   1944 C  C   . PRO A 1 300 ? 91.874  93.662  97.679  1.00 85.37 ? 288 PRO A C   1 
ATOM   1945 O  O   . PRO A 1 300 ? 93.096  93.612  97.688  1.00 85.37 ? 288 PRO A O   1 
ATOM   1946 C  CB  . PRO A 1 300 ? 90.814  93.754  95.417  1.00 85.37 ? 288 PRO A CB  1 
ATOM   1947 C  CG  . PRO A 1 300 ? 89.449  93.370  94.969  1.00 85.37 ? 288 PRO A CG  1 
ATOM   1948 C  CD  . PRO A 1 300 ? 88.718  92.954  96.202  1.00 85.37 ? 288 PRO A CD  1 
ATOM   1949 N  N   . GLN A 1 301 ? 91.176  94.390  98.536  1.00 85.99 ? 289 GLN A N   1 
ATOM   1950 C  CA  . GLN A 1 301 ? 91.833  95.239  99.521  1.00 85.99 ? 289 GLN A CA  1 
ATOM   1951 C  C   . GLN A 1 301 ? 92.729  94.524  100.510 1.00 85.99 ? 289 GLN A C   1 
ATOM   1952 O  O   . GLN A 1 301 ? 93.796  95.018  100.829 1.00 85.99 ? 289 GLN A O   1 
ATOM   1953 C  CB  . GLN A 1 301 ? 90.794  96.060  100.280 1.00 85.99 ? 289 GLN A CB  1 
ATOM   1954 C  CG  . GLN A 1 301 ? 89.444  95.379  100.404 1.00 85.99 ? 289 GLN A CG  1 
ATOM   1955 C  CD  . GLN A 1 301 ? 88.345  96.348  100.782 1.00 85.99 ? 289 GLN A CD  1 
ATOM   1956 O  OE1 . GLN A 1 301 ? 88.608  97.503  101.111 1.00 85.99 ? 289 GLN A OE1 1 
ATOM   1957 N  NE2 . GLN A 1 301 ? 87.103  95.882  100.734 1.00 85.99 ? 289 GLN A NE2 1 
ATOM   1958 N  N   . VAL A 1 302 ? 92.315  93.361  100.988 1.00 90.80 ? 290 VAL A N   1 
ATOM   1959 C  CA  . VAL A 1 302 ? 93.102  92.643  101.971 1.00 90.80 ? 290 VAL A CA  1 
ATOM   1960 C  C   . VAL A 1 302 ? 94.444  92.294  101.374 1.00 90.80 ? 290 VAL A C   1 
ATOM   1961 O  O   . VAL A 1 302 ? 95.466  92.437  102.025 1.00 90.80 ? 290 VAL A O   1 
ATOM   1962 C  CB  . VAL A 1 302 ? 92.394  91.350  102.399 1.00 90.80 ? 290 VAL A CB  1 
ATOM   1963 C  CG1 . VAL A 1 302 ? 93.125  90.689  103.553 1.00 90.80 ? 290 VAL A CG1 1 
ATOM   1964 C  CG2 . VAL A 1 302 ? 90.958  91.650  102.784 1.00 90.80 ? 290 VAL A CG2 1 
ATOM   1965 N  N   . TRP A 1 303 ? 94.450  91.847  100.128 1.00 88.60 ? 291 TRP A N   1 
ATOM   1966 C  CA  . TRP A 1 303 ? 95.694  91.493  99.467  1.00 88.60 ? 291 TRP A CA  1 
ATOM   1967 C  C   . TRP A 1 303 ? 96.624  92.664  99.251  1.00 88.60 ? 291 TRP A C   1 
ATOM   1968 O  O   . TRP A 1 303 ? 97.816  92.571  99.519  1.00 88.60 ? 291 TRP A O   1 
ATOM   1969 C  CB  . TRP A 1 303 ? 95.391  90.819  98.129  1.00 88.60 ? 291 TRP A CB  1 
ATOM   1970 C  CG  . TRP A 1 303 ? 94.796  89.466  98.283  1.00 88.60 ? 291 TRP A CG  1 
ATOM   1971 C  CD1 . TRP A 1 303 ? 93.477  89.163  98.425  1.00 88.60 ? 291 TRP A CD1 1 
ATOM   1972 C  CD2 . TRP A 1 303 ? 95.502  88.223  98.326  1.00 88.60 ? 291 TRP A CD2 1 
ATOM   1973 N  NE1 . TRP A 1 303 ? 93.315  87.807  98.551  1.00 88.60 ? 291 TRP A NE1 1 
ATOM   1974 C  CE2 . TRP A 1 303 ? 94.545  87.207  98.494  1.00 88.60 ? 291 TRP A CE2 1 
ATOM   1975 C  CE3 . TRP A 1 303 ? 96.852  87.870  98.236  1.00 88.60 ? 291 TRP A CE3 1 
ATOM   1976 C  CZ2 . TRP A 1 303 ? 94.893  85.863  98.576  1.00 88.60 ? 291 TRP A CZ2 1 
ATOM   1977 C  CZ3 . TRP A 1 303 ? 97.195  86.538  98.320  1.00 88.60 ? 291 TRP A CZ3 1 
ATOM   1978 C  CH2 . TRP A 1 303 ? 96.220  85.550  98.487  1.00 88.60 ? 291 TRP A CH2 1 
ATOM   1979 N  N   . ILE A 1 304 ? 96.082  93.775  98.773  1.00 85.21 ? 292 ILE A N   1 
ATOM   1980 C  CA  . ILE A 1 304 ? 96.901  94.952  98.537  1.00 85.21 ? 292 ILE A CA  1 
ATOM   1981 C  C   . ILE A 1 304 ? 97.443  95.509  99.839  1.00 85.21 ? 292 ILE A C   1 
ATOM   1982 O  O   . ILE A 1 304 ? 98.624  95.801  99.945  1.00 85.21 ? 292 ILE A O   1 
ATOM   1983 C  CB  . ILE A 1 304 ? 96.131  96.030  97.753  1.00 85.21 ? 292 ILE A CB  1 
ATOM   1984 C  CG1 . ILE A 1 304 ? 95.745  95.500  96.376  1.00 85.21 ? 292 ILE A CG1 1 
ATOM   1985 C  CG2 . ILE A 1 304 ? 96.967  97.288  97.589  1.00 85.21 ? 292 ILE A CG2 1 
ATOM   1986 C  CD1 . ILE A 1 304 ? 95.588  96.590  95.343  1.00 85.21 ? 292 ILE A CD1 1 
ATOM   1987 N  N   . ASP A 1 305 ? 96.595  95.593  100.853 1.00 89.12 ? 293 ASP A N   1 
ATOM   1988 C  CA  . ASP A 1 305 ? 97.025  96.101  102.140 1.00 89.12 ? 293 ASP A CA  1 
ATOM   1989 C  C   . ASP A 1 305 ? 98.069  95.228  102.801 1.00 89.12 ? 293 ASP A C   1 
ATOM   1990 O  O   . ASP A 1 305 ? 99.016  95.738  103.377 1.00 89.12 ? 293 ASP A O   1 
ATOM   1991 C  CB  . ASP A 1 305 ? 95.828  96.288  103.062 1.00 89.12 ? 293 ASP A CB  1 
ATOM   1992 C  CG  . ASP A 1 305 ? 94.971  97.473  102.669 1.00 89.12 ? 293 ASP A CG  1 
ATOM   1993 O  OD1 . ASP A 1 305 ? 95.195  98.035  101.579 1.00 89.12 ? 293 ASP A OD1 1 
ATOM   1994 O  OD2 . ASP A 1 305 ? 94.071  97.847  103.446 1.00 89.12 ? 293 ASP A OD2 1 
ATOM   1995 N  N   . ALA A 1 306 ? 97.887  93.915  102.748 1.00 92.32 ? 294 ALA A N   1 
ATOM   1996 C  CA  . ALA A 1 306 ? 98.850  92.992  103.337 1.00 92.32 ? 294 ALA A CA  1 
ATOM   1997 C  C   . ALA A 1 306 ? 100.191 92.957  102.664 1.00 92.32 ? 294 ALA A C   1 
ATOM   1998 O  O   . ALA A 1 306 ? 101.225 92.987  103.324 1.00 92.32 ? 294 ALA A O   1 
ATOM   1999 C  CB  . ALA A 1 306 ? 98.258  91.610  103.377 1.00 92.32 ? 294 ALA A CB  1 
ATOM   2000 N  N   . GLY A 1 307 ? 100.182 92.896  101.345 1.00 89.00 ? 295 GLY A N   1 
ATOM   2001 C  CA  . GLY A 1 307 ? 101.421 92.892  100.608 1.00 89.00 ? 295 GLY A CA  1 
ATOM   2002 C  C   . GLY A 1 307 ? 102.163 94.173  100.715 1.00 89.00 ? 295 GLY A C   1 
ATOM   2003 O  O   . GLY A 1 307 ? 103.378 94.188  100.835 1.00 89.00 ? 295 GLY A O   1 
ATOM   2004 N  N   . THR A 1 308 ? 101.432 95.264  100.627 1.00 87.55 ? 296 THR A N   1 
ATOM   2005 C  CA  . THR A 1 308 ? 102.038 96.572  100.766 1.00 87.55 ? 296 THR A CA  1 
ATOM   2006 C  C   . THR A 1 308 ? 102.573 96.845  102.173 1.00 87.55 ? 296 THR A C   1 
ATOM   2007 O  O   . THR A 1 308 ? 103.604 97.478  102.330 1.00 87.55 ? 296 THR A O   1 
ATOM   2008 C  CB  . THR A 1 308 ? 101.121 97.666  100.237 1.00 87.55 ? 296 THR A CB  1 
ATOM   2009 O  OG1 . THR A 1 308 ? 101.151 97.649  98.804  1.00 87.55 ? 296 THR A OG1 1 
ATOM   2010 C  CG2 . THR A 1 308 ? 101.616 98.944  100.693 1.00 87.55 ? 296 THR A CG2 1 
ATOM   2011 N  N   . GLN A 1 309 ? 101.899 96.347  103.201 1.00 92.78 ? 297 GLN A N   1 
ATOM   2012 C  CA  . GLN A 1 309 ? 102.413 96.513  104.551 1.00 92.78 ? 297 GLN A CA  1 
ATOM   2013 C  C   . GLN A 1 309 ? 103.770 95.853  104.608 1.00 92.78 ? 297 GLN A C   1 
ATOM   2014 O  O   . GLN A 1 309 ? 104.694 96.402  105.182 1.00 92.78 ? 297 GLN A O   1 
ATOM   2015 C  CB  . GLN A 1 309 ? 101.466 95.887  105.580 1.00 92.78 ? 297 GLN A CB  1 
ATOM   2016 C  CG  . GLN A 1 309 ? 102.037 95.735  106.979 1.00 92.78 ? 297 GLN A CG  1 
ATOM   2017 C  CD  . GLN A 1 309 ? 102.400 97.061  107.611 1.00 92.78 ? 297 GLN A CD  1 
ATOM   2018 O  OE1 . GLN A 1 309 ? 101.771 98.075  107.345 1.00 92.78 ? 297 GLN A OE1 1 
ATOM   2019 N  NE2 . GLN A 1 309 ? 103.417 97.053  108.461 1.00 92.78 ? 297 GLN A NE2 1 
ATOM   2020 N  N   . ILE A 1 310 ? 103.939 94.685  104.016 1.00 93.58 ? 298 ILE A N   1 
ATOM   2021 C  CA  . ILE A 1 310 ? 105.262 94.068  103.978 1.00 93.58 ? 298 ILE A CA  1 
ATOM   2022 C  C   . ILE A 1 310 ? 106.278 95.017  103.355 1.00 93.58 ? 298 ILE A C   1 
ATOM   2023 O  O   . ILE A 1 310 ? 107.347 95.238  103.913 1.00 93.58 ? 298 ILE A O   1 
ATOM   2024 C  CB  . ILE A 1 310 ? 105.237 92.696  103.267 1.00 93.58 ? 298 ILE A CB  1 
ATOM   2025 C  CG1 . ILE A 1 310 ? 104.825 91.616  104.250 1.00 93.58 ? 298 ILE A CG1 1 
ATOM   2026 C  CG2 . ILE A 1 310 ? 106.608 92.322  102.736 1.00 93.58 ? 298 ILE A CG2 1 
ATOM   2027 C  CD1 . ILE A 1 310 ? 105.838 91.434  105.354 1.00 93.58 ? 298 ILE A CD1 1 
ATOM   2028 N  N   . PHE A 1 311 ? 105.933 95.608  102.219 1.00 91.54 ? 299 PHE A N   1 
ATOM   2029 C  CA  . PHE A 1 311 ? 106.828 96.547  101.551 1.00 91.54 ? 299 PHE A CA  1 
ATOM   2030 C  C   . PHE A 1 311 ? 107.088 97.775  102.406 1.00 91.54 ? 299 PHE A C   1 
ATOM   2031 O  O   . PHE A 1 311 ? 108.200 98.279  102.433 1.00 91.54 ? 299 PHE A O   1 
ATOM   2032 C  CB  . PHE A 1 311 ? 106.275 96.960  100.188 1.00 91.54 ? 299 PHE A CB  1 
ATOM   2033 C  CG  . PHE A 1 311 ? 106.085 95.822  99.224  1.00 91.54 ? 299 PHE A CG  1 
ATOM   2034 C  CD1 . PHE A 1 311 ? 106.818 94.654  99.338  1.00 91.54 ? 299 PHE A CD1 1 
ATOM   2035 C  CD2 . PHE A 1 311 ? 105.183 95.936  98.182  1.00 91.54 ? 299 PHE A CD2 1 
ATOM   2036 C  CE1 . PHE A 1 311 ? 106.644 93.616  98.444  1.00 91.54 ? 299 PHE A CE1 1 
ATOM   2037 C  CE2 . PHE A 1 311 ? 105.005 94.904  97.283  1.00 91.54 ? 299 PHE A CE2 1 
ATOM   2038 C  CZ  . PHE A 1 311 ? 105.737 93.742  97.414  1.00 91.54 ? 299 PHE A CZ  1 
ATOM   2039 N  N   . PHE A 1 312 ? 106.072 98.264  103.099 1.00 89.78 ? 300 PHE A N   1 
ATOM   2040 C  CA  . PHE A 1 312 ? 106.236 99.418  103.961 1.00 89.78 ? 300 PHE A CA  1 
ATOM   2041 C  C   . PHE A 1 312 ? 107.207 99.147  105.085 1.00 89.78 ? 300 PHE A C   1 
ATOM   2042 O  O   . PHE A 1 312 ? 108.200 99.827  105.217 1.00 89.78 ? 300 PHE A O   1 
ATOM   2043 C  CB  . PHE A 1 312 ? 104.890 99.875  104.507 1.00 89.78 ? 300 PHE A CB  1 
ATOM   2044 C  CG  . PHE A 1 312 ? 104.916 101.233 105.143 1.00 89.78 ? 300 PHE A CG  1 
ATOM   2045 C  CD1 . PHE A 1 312 ? 105.365 101.404 106.445 1.00 89.78 ? 300 PHE A CD1 1 
ATOM   2046 C  CD2 . PHE A 1 312 ? 104.457 102.335 104.451 1.00 89.78 ? 300 PHE A CD2 1 
ATOM   2047 C  CE1 . PHE A 1 312 ? 105.371 102.651 107.032 1.00 89.78 ? 300 PHE A CE1 1 
ATOM   2048 C  CE2 . PHE A 1 312 ? 104.458 103.582 105.034 1.00 89.78 ? 300 PHE A CE2 1 
ATOM   2049 C  CZ  . PHE A 1 312 ? 104.916 103.741 106.325 1.00 89.78 ? 300 PHE A CZ  1 
ATOM   2050 N  N   . SER A 1 313 ? 106.975 98.106  105.860 1.00 93.99 ? 301 SER A N   1 
ATOM   2051 C  CA  . SER A 1 313 ? 107.819 97.857  107.008 1.00 93.99 ? 301 SER A CA  1 
ATOM   2052 C  C   . SER A 1 313 ? 109.261 97.662  106.569 1.00 93.99 ? 301 SER A C   1 
ATOM   2053 O  O   . SER A 1 313 ? 110.182 98.074  107.268 1.00 93.99 ? 301 SER A O   1 
ATOM   2054 C  CB  . SER A 1 313 ? 107.303 96.659  107.773 1.00 93.99 ? 301 SER A CB  1 
ATOM   2055 O  OG  . SER A 1 313 ? 108.082 96.429  108.926 1.00 93.99 ? 301 SER A OG  1 
ATOM   2056 N  N   . TYR A 1 314 ? 109.467 97.029  105.427 1.00 93.31 ? 302 TYR A N   1 
ATOM   2057 C  CA  . TYR A 1 314 ? 110.813 96.813  104.893 1.00 93.31 ? 302 TYR A CA  1 
ATOM   2058 C  C   . TYR A 1 314 ? 111.571 98.007  104.306 1.00 93.31 ? 302 TYR A C   1 
ATOM   2059 O  O   . TYR A 1 314 ? 112.764 97.874  104.072 1.00 93.31 ? 302 TYR A O   1 
ATOM   2060 C  CB  . TYR A 1 314 ? 110.777 95.708  103.848 1.00 93.31 ? 302 TYR A CB  1 
ATOM   2061 C  CG  . TYR A 1 314 ? 110.683 94.328  104.419 1.00 93.31 ? 302 TYR A CG  1 
ATOM   2062 C  CD1 . TYR A 1 314 ? 110.515 94.133  105.777 1.00 93.31 ? 302 TYR A CD1 1 
ATOM   2063 C  CD2 . TYR A 1 314 ? 110.768 93.218  103.602 1.00 93.31 ? 302 TYR A CD2 1 
ATOM   2064 C  CE1 . TYR A 1 314 ? 110.424 92.874  106.308 1.00 93.31 ? 302 TYR A CE1 1 
ATOM   2065 C  CE2 . TYR A 1 314 ? 110.683 91.950  104.126 1.00 93.31 ? 302 TYR A CE2 1 
ATOM   2066 C  CZ  . TYR A 1 314 ? 110.510 91.794  105.479 1.00 93.31 ? 302 TYR A CZ  1 
ATOM   2067 O  OH  . TYR A 1 314 ? 110.430 90.549  106.016 1.00 93.31 ? 302 TYR A OH  1 
ATOM   2068 N  N   . ALA A 1 315 ? 110.858 99.115  104.092 1.00 92.95 ? 303 ALA A N   1 
ATOM   2069 C  CA  . ALA A 1 315 ? 111.429 100.307 103.479 1.00 92.95 ? 303 ALA A CA  1 
ATOM   2070 C  C   . ALA A 1 315 ? 111.913 99.982  102.092 1.00 92.95 ? 303 ALA A C   1 
ATOM   2071 O  O   . ALA A 1 315 ? 112.802 100.639 101.562 1.00 92.95 ? 303 ALA A O   1 
ATOM   2072 C  CB  . ALA A 1 315 ? 112.500 100.936 104.339 1.00 92.95 ? 303 ALA A CB  1 
ATOM   2073 N  N   . ILE A 1 316 ? 111.343 98.942  101.504 1.00 94.25 ? 304 ILE A N   1 
ATOM   2074 C  CA  . ILE A 1 316 ? 111.689 98.614  100.134 1.00 94.25 ? 304 ILE A CA  1 
ATOM   2075 C  C   . ILE A 1 316 ? 110.939 99.514  99.175  1.00 94.25 ? 304 ILE A C   1 
ATOM   2076 O  O   . ILE A 1 316 ? 109.873 100.011 99.537  1.00 94.25 ? 304 ILE A O   1 
ATOM   2077 C  CB  . ILE A 1 316 ? 111.546 97.113  99.798  1.00 94.25 ? 304 ILE A CB  1 
ATOM   2078 C  CG1 . ILE A 1 316 ? 110.200 96.557  100.221 1.00 94.25 ? 304 ILE A CG1 1 
ATOM   2079 C  CG2 . ILE A 1 316 ? 112.654 96.323  100.469 1.00 94.25 ? 304 ILE A CG2 1 
ATOM   2080 C  CD1 . ILE A 1 316 ? 110.159 95.048  100.146 1.00 94.25 ? 304 ILE A CD1 1 
ATOM   2081 N  N   . CYS A 1 317 ? 111.509 99.768  97.997  1.00 95.42 ? 305 CYS A N   1 
ATOM   2082 C  CA  . CYS A 1 317 ? 110.909 100.656 96.989  1.00 95.42 ? 305 CYS A CA  1 
ATOM   2083 C  C   . CYS A 1 317 ? 111.098 102.123 97.364  1.00 95.42 ? 305 CYS A C   1 
ATOM   2084 O  O   . CYS A 1 317 ? 110.524 103.003 96.729  1.00 95.42 ? 305 CYS A O   1 
ATOM   2085 C  CB  . CYS A 1 317 ? 109.443 100.316 96.674  1.00 95.42 ? 305 CYS A CB  1 
ATOM   2086 S  SG  . CYS A 1 317 ? 109.122 98.581  96.284  1.00 95.42 ? 305 CYS A SG  1 
ATOM   2087 N  N   . LEU A 1 318 ? 111.889 102.386 98.402  1.00 95.73 ? 306 LEU A N   1 
ATOM   2088 C  CA  . LEU A 1 318 ? 112.168 103.756 98.822  1.00 95.73 ? 306 LEU A CA  1 
ATOM   2089 C  C   . LEU A 1 318 ? 113.592 104.188 98.497  1.00 95.73 ? 306 LEU A C   1 
ATOM   2090 O  O   . LEU A 1 318 ? 113.944 105.344 98.667  1.00 95.73 ? 306 LEU A O   1 
ATOM   2091 C  CB  . LEU A 1 318 ? 111.937 103.892 100.321 1.00 95.73 ? 306 LEU A CB  1 
ATOM   2092 C  CG  . LEU A 1 318 ? 110.521 103.660 100.826 1.00 95.73 ? 306 LEU A CG  1 
ATOM   2093 C  CD1 . LEU A 1 318 ? 110.498 103.831 102.334 1.00 95.73 ? 306 LEU A CD1 1 
ATOM   2094 C  CD2 . LEU A 1 318 ? 109.562 104.629 100.156 1.00 95.73 ? 306 LEU A CD2 1 
ATOM   2095 N  N   . GLY A 1 319 ? 114.417 103.266 98.024  1.00 95.50 ? 307 GLY A N   1 
ATOM   2096 C  CA  . GLY A 1 319 ? 115.801 103.592 97.745  1.00 95.50 ? 307 GLY A CA  1 
ATOM   2097 C  C   . GLY A 1 319 ? 116.697 103.523 98.965  1.00 95.50 ? 307 GLY A C   1 
ATOM   2098 O  O   . GLY A 1 319 ? 117.904 103.722 98.849  1.00 95.50 ? 307 GLY A O   1 
ATOM   2099 N  N   . ALA A 1 320 ? 116.126 103.249 100.135 1.00 96.34 ? 308 ALA A N   1 
ATOM   2100 C  CA  . ALA A 1 320 ? 116.928 103.107 101.344 1.00 96.34 ? 308 ALA A CA  1 
ATOM   2101 C  C   . ALA A 1 320 ? 117.773 101.863 101.308 1.00 96.34 ? 308 ALA A C   1 
ATOM   2102 O  O   . ALA A 1 320 ? 118.938 101.889 101.685 1.00 96.34 ? 308 ALA A O   1 
ATOM   2103 C  CB  . ALA A 1 320 ? 116.020 103.051 102.555 1.00 96.34 ? 308 ALA A CB  1 
ATOM   2104 N  N   . MET A 1 321 ? 117.195 100.757 100.862 1.00 96.81 ? 309 MET A N   1 
ATOM   2105 C  CA  . MET A 1 321 ? 117.910 99.488  100.888 1.00 96.81 ? 309 MET A CA  1 
ATOM   2106 C  C   . MET A 1 321 ? 119.069 99.413  99.913  1.00 96.81 ? 309 MET A C   1 
ATOM   2107 O  O   . MET A 1 321 ? 120.088 98.802  100.214 1.00 96.81 ? 309 MET A O   1 
ATOM   2108 C  CB  . MET A 1 321 ? 116.928 98.337  100.709 1.00 96.81 ? 309 MET A CB  1 
ATOM   2109 C  CG  . MET A 1 321 ? 115.868 98.315  101.790 1.00 96.81 ? 309 MET A CG  1 
ATOM   2110 S  SD  . MET A 1 321 ? 116.659 98.386  103.406 1.00 96.81 ? 309 MET A SD  1 
ATOM   2111 C  CE  . MET A 1 321 ? 115.550 99.462  104.299 1.00 96.81 ? 309 MET A CE  1 
ATOM   2112 N  N   . THR A 1 322 ? 118.936 100.038 98.753  1.00 97.66 ? 310 THR A N   1 
ATOM   2113 C  CA  . THR A 1 322 ? 120.056 100.071 97.824  1.00 97.66 ? 310 THR A CA  1 
ATOM   2114 C  C   . THR A 1 322 ? 121.205 100.835 98.450  1.00 97.66 ? 310 THR A C   1 
ATOM   2115 O  O   . THR A 1 322 ? 122.355 100.428 98.329  1.00 97.66 ? 310 THR A O   1 
ATOM   2116 C  CB  . THR A 1 322 ? 119.669 100.698 96.477  1.00 97.66 ? 310 THR A CB  1 
ATOM   2117 O  OG1 . THR A 1 322 ? 119.049 101.967 96.705  1.00 97.66 ? 310 THR A OG1 1 
ATOM   2118 C  CG2 . THR A 1 322 ? 118.701 99.804  95.732  1.00 97.66 ? 310 THR A CG2 1 
ATOM   2119 N  N   . SER A 1 323 ? 120.903 101.938 99.125  1.00 96.84 ? 311 SER A N   1 
ATOM   2120 C  CA  . SER A 1 323 ? 121.934 102.721 99.801  1.00 96.84 ? 311 SER A CA  1 
ATOM   2121 C  C   . SER A 1 323 ? 122.607 101.952 100.925 1.00 96.84 ? 311 SER A C   1 
ATOM   2122 O  O   . SER A 1 323 ? 123.820 102.035 101.085 1.00 96.84 ? 311 SER A O   1 
ATOM   2123 C  CB  . SER A 1 323 ? 121.341 104.018 100.337 1.00 96.84 ? 311 SER A CB  1 
ATOM   2124 O  OG  . SER A 1 323 ? 120.741 104.765 99.295  1.00 96.84 ? 311 SER A OG  1 
ATOM   2125 N  N   . LEU A 1 324 ? 121.834 101.205 101.706 1.00 96.94 ? 312 LEU A N   1 
ATOM   2126 C  CA  . LEU A 1 324 ? 122.411 100.385 102.765 1.00 96.94 ? 312 LEU A CA  1 
ATOM   2127 C  C   . LEU A 1 324 ? 123.320 99.334  102.178 1.00 96.94 ? 312 LEU A C   1 
ATOM   2128 O  O   . LEU A 1 324 ? 124.381 99.053  102.729 1.00 96.94 ? 312 LEU A O   1 
ATOM   2129 C  CB  . LEU A 1 324 ? 121.322 99.718  103.594 1.00 96.94 ? 312 LEU A CB  1 
ATOM   2130 C  CG  . LEU A 1 324 ? 120.599 100.595 104.609 1.00 96.94 ? 312 LEU A CG  1 
ATOM   2131 C  CD1 . LEU A 1 324 ? 119.529 99.783  105.317 1.00 96.94 ? 312 LEU A CD1 1 
ATOM   2132 C  CD2 . LEU A 1 324 ? 121.594 101.158 105.612 1.00 96.94 ? 312 LEU A CD2 1 
ATOM   2133 N  N   . GLY A 1 325 ? 122.917 98.749  101.059 1.00 97.35 ? 313 GLY A N   1 
ATOM   2134 C  CA  . GLY A 1 325 ? 123.742 97.763  100.395 1.00 97.35 ? 313 GLY A CA  1 
ATOM   2135 C  C   . GLY A 1 325 ? 125.044 98.376  99.949  1.00 97.35 ? 313 GLY A C   1 
ATOM   2136 O  O   . GLY A 1 325 ? 126.082 97.735  100.019 1.00 97.35 ? 313 GLY A O   1 
ATOM   2137 N  N   . SER A 1 326 ? 125.000 99.620  99.493  1.00 96.46 ? 314 SER A N   1 
ATOM   2138 C  CA  . SER A 1 326 ? 126.198 100.295 99.017  1.00 96.46 ? 314 SER A CA  1 
ATOM   2139 C  C   . SER A 1 326 ? 127.223 100.400 100.123 1.00 96.46 ? 314 SER A C   1 
ATOM   2140 O  O   . SER A 1 326 ? 128.417 100.250 99.879  1.00 96.46 ? 314 SER A O   1 
ATOM   2141 C  CB  . SER A 1 326 ? 125.838 101.688 98.526  1.00 96.46 ? 314 SER A CB  1 
ATOM   2142 O  OG  . SER A 1 326 ? 127.000 102.467 98.313  1.00 96.46 ? 314 SER A OG  1 
ATOM   2143 N  N   . TYR A 1 327 ? 126.769 100.663 101.341 1.00 96.06 ? 315 TYR A N   1 
ATOM   2144 C  CA  . TYR A 1 327 ? 127.671 100.744 102.484 1.00 96.06 ? 315 TYR A CA  1 
ATOM   2145 C  C   . TYR A 1 327 ? 128.354 99.415  102.737 1.00 96.06 ? 315 TYR A C   1 
ATOM   2146 O  O   . TYR A 1 327 ? 129.518 99.381  103.125 1.00 96.06 ? 315 TYR A O   1 
ATOM   2147 C  CB  . TYR A 1 327 ? 126.928 101.209 103.732 1.00 96.06 ? 315 TYR A CB  1 
ATOM   2148 C  CG  . TYR A 1 327 ? 126.228 102.533 103.562 1.00 96.06 ? 315 TYR A CG  1 
ATOM   2149 C  CD1 . TYR A 1 327 ? 126.842 103.583 102.896 1.00 96.06 ? 315 TYR A CD1 1 
ATOM   2150 C  CD2 . TYR A 1 327 ? 124.959 102.738 104.080 1.00 96.06 ? 315 TYR A CD2 1 
ATOM   2151 C  CE1 . TYR A 1 327 ? 126.204 104.796 102.737 1.00 96.06 ? 315 TYR A CE1 1 
ATOM   2152 C  CE2 . TYR A 1 327 ? 124.313 103.948 103.927 1.00 96.06 ? 315 TYR A CE2 1 
ATOM   2153 C  CZ  . TYR A 1 327 ? 124.941 104.973 103.256 1.00 96.06 ? 315 TYR A CZ  1 
ATOM   2154 O  OH  . TYR A 1 327 ? 124.304 106.182 103.104 1.00 96.06 ? 315 TYR A OH  1 
ATOM   2155 N  N   . ASN A 1 328 ? 127.631 98.318  102.538 1.00 95.67 ? 316 ASN A N   1 
ATOM   2156 C  CA  . ASN A 1 328 ? 128.200 96.986  102.739 1.00 95.67 ? 316 ASN A CA  1 
ATOM   2157 C  C   . ASN A 1 328 ? 129.339 96.711  101.775 1.00 95.67 ? 316 ASN A C   1 
ATOM   2158 O  O   . ASN A 1 328 ? 129.309 97.147  100.627 1.00 95.67 ? 316 ASN A O   1 
ATOM   2159 C  CB  . ASN A 1 328 ? 127.124 95.911  102.564 1.00 95.67 ? 316 ASN A CB  1 
ATOM   2160 C  CG  . ASN A 1 328 ? 125.953 96.094  103.505 1.00 95.67 ? 316 ASN A CG  1 
ATOM   2161 O  OD1 . ASN A 1 328 ? 126.004 96.901  104.432 1.00 95.67 ? 316 ASN A OD1 1 
ATOM   2162 N  ND2 . ASN A 1 328 ? 124.889 95.339  103.272 1.00 95.67 ? 316 ASN A ND2 1 
ATOM   2163 N  N   . LYS A 1 329 ? 130.345 95.981  102.234 1.00 93.38 ? 317 LYS A N   1 
ATOM   2164 C  CA  . LYS A 1 329 ? 131.485 95.648  101.386 1.00 93.38 ? 317 LYS A CA  1 
ATOM   2165 C  C   . LYS A 1 329 ? 131.085 94.663  100.304 1.00 93.38 ? 317 LYS A C   1 
ATOM   2166 O  O   . LYS A 1 329 ? 130.095 93.954  100.450 1.00 93.38 ? 317 LYS A O   1 
ATOM   2167 C  CB  . LYS A 1 329 ? 132.616 95.077  102.233 1.00 93.38 ? 317 LYS A CB  1 
ATOM   2168 C  CG  . LYS A 1 329 ? 132.157 94.034  103.236 1.00 93.38 ? 317 LYS A CG  1 
ATOM   2169 C  CD  . LYS A 1 329 ? 133.300 93.570  104.121 1.00 93.38 ? 317 LYS A CD  1 
ATOM   2170 C  CE  . LYS A 1 329 ? 133.855 94.719  104.946 1.00 93.38 ? 317 LYS A CE  1 
ATOM   2171 N  NZ  . LYS A 1 329 ? 134.942 94.269  105.858 1.00 93.38 ? 317 LYS A NZ  1 
ATOM   2172 N  N   . TYR A 1 330 ? 131.845 94.599  99.218  1.00 91.50 ? 318 TYR A N   1 
ATOM   2173 C  CA  . TYR A 1 330 ? 131.458 93.742  98.099  1.00 91.50 ? 318 TYR A CA  1 
ATOM   2174 C  C   . TYR A 1 330 ? 131.370 92.282  98.502  1.00 91.50 ? 318 TYR A C   1 
ATOM   2175 O  O   . TYR A 1 330 ? 130.437 91.589  98.114  1.00 91.50 ? 318 TYR A O   1 
ATOM   2176 C  CB  . TYR A 1 330 ? 132.448 93.904  96.948  1.00 91.50 ? 318 TYR A CB  1 
ATOM   2177 C  CG  . TYR A 1 330 ? 132.071 93.177  95.677  1.00 91.50 ? 318 TYR A CG  1 
ATOM   2178 C  CD1 . TYR A 1 330 ? 131.090 93.677  94.834  1.00 91.50 ? 318 TYR A CD1 1 
ATOM   2179 C  CD2 . TYR A 1 330 ? 132.712 92.002  95.310  1.00 91.50 ? 318 TYR A CD2 1 
ATOM   2180 C  CE1 . TYR A 1 330 ? 130.749 93.021  93.669  1.00 91.50 ? 318 TYR A CE1 1 
ATOM   2181 C  CE2 . TYR A 1 330 ? 132.376 91.338  94.147  1.00 91.50 ? 318 TYR A CE2 1 
ATOM   2182 C  CZ  . TYR A 1 330 ? 131.396 91.853  93.331  1.00 91.50 ? 318 TYR A CZ  1 
ATOM   2183 O  OH  . TYR A 1 330 ? 131.062 91.192  92.173  1.00 91.50 ? 318 TYR A OH  1 
ATOM   2184 N  N   . LYS A 1 331 ? 132.321 91.824  99.305  1.00 93.68 ? 319 LYS A N   1 
ATOM   2185 C  CA  . LYS A 1 331 ? 132.333 90.434  99.744  1.00 93.68 ? 319 LYS A CA  1 
ATOM   2186 C  C   . LYS A 1 331 ? 131.719 90.276  101.122 1.00 93.68 ? 319 LYS A C   1 
ATOM   2187 O  O   . LYS A 1 331 ? 132.420 89.990  102.086 1.00 93.68 ? 319 LYS A O   1 
ATOM   2188 C  CB  . LYS A 1 331 ? 133.760 89.894  99.731  1.00 93.68 ? 319 LYS A CB  1 
ATOM   2189 C  CG  . LYS A 1 331 ? 134.315 89.679  98.334  1.00 93.68 ? 319 LYS A CG  1 
ATOM   2190 C  CD  . LYS A 1 331 ? 133.485 88.657  97.576  1.00 93.68 ? 319 LYS A CD  1 
ATOM   2191 C  CE  . LYS A 1 331 ? 133.992 88.469  96.157  1.00 93.68 ? 319 LYS A CE  1 
ATOM   2192 N  NZ  . LYS A 1 331 ? 135.416 88.039  96.126  1.00 93.68 ? 319 LYS A NZ  1 
ATOM   2193 N  N   . TYR A 1 332 ? 130.410 90.460  101.217 1.00 95.02 ? 320 TYR A N   1 
ATOM   2194 C  CA  . TYR A 1 332 ? 129.723 90.330  102.491 1.00 95.02 ? 320 TYR A CA  1 
ATOM   2195 C  C   . TYR A 1 332 ? 128.524 89.413  102.318 1.00 95.02 ? 320 TYR A C   1 
ATOM   2196 O  O   . TYR A 1 332 ? 127.874 89.436  101.278 1.00 95.02 ? 320 TYR A O   1 
ATOM   2197 C  CB  . TYR A 1 332 ? 129.279 91.709  102.972 1.00 95.02 ? 320 TYR A CB  1 
ATOM   2198 C  CG  . TYR A 1 332 ? 128.692 91.738  104.356 1.00 95.02 ? 320 TYR A CG  1 
ATOM   2199 C  CD1 . TYR A 1 332 ? 129.478 91.470  105.465 1.00 95.02 ? 320 TYR A CD1 1 
ATOM   2200 C  CD2 . TYR A 1 332 ? 127.357 92.050  104.557 1.00 95.02 ? 320 TYR A CD2 1 
ATOM   2201 C  CE1 . TYR A 1 332 ? 128.947 91.497  106.737 1.00 95.02 ? 320 TYR A CE1 1 
ATOM   2202 C  CE2 . TYR A 1 332 ? 126.816 92.079  105.825 1.00 95.02 ? 320 TYR A CE2 1 
ATOM   2203 C  CZ  . TYR A 1 332 ? 127.618 91.803  106.911 1.00 95.02 ? 320 TYR A CZ  1 
ATOM   2204 O  OH  . TYR A 1 332 ? 127.093 91.832  108.182 1.00 95.02 ? 320 TYR A OH  1 
ATOM   2205 N  N   . ASN A 1 333 ? 128.230 88.602  103.329 1.00 96.97 ? 321 ASN A N   1 
ATOM   2206 C  CA  . ASN A 1 333 ? 127.062 87.732  103.275 1.00 96.97 ? 321 ASN A CA  1 
ATOM   2207 C  C   . ASN A 1 333 ? 125.832 88.518  103.664 1.00 96.97 ? 321 ASN A C   1 
ATOM   2208 O  O   . ASN A 1 333 ? 125.307 88.357  104.760 1.00 96.97 ? 321 ASN A O   1 
ATOM   2209 C  CB  . ASN A 1 333 ? 127.238 86.520  104.186 1.00 96.97 ? 321 ASN A CB  1 
ATOM   2210 C  CG  . ASN A 1 333 ? 126.214 85.431  103.923 1.00 96.97 ? 321 ASN A CG  1 
ATOM   2211 O  OD1 . ASN A 1 333 ? 125.442 85.499  102.970 1.00 96.97 ? 321 ASN A OD1 1 
ATOM   2212 N  ND2 . ASN A 1 333 ? 126.210 84.413  104.772 1.00 96.97 ? 321 ASN A ND2 1 
ATOM   2213 N  N   . SER A 1 334 ? 125.376 89.383  102.772 1.00 96.37 ? 322 SER A N   1 
ATOM   2214 C  CA  . SER A 1 334 ? 124.164 90.148  103.021 1.00 96.37 ? 322 SER A CA  1 
ATOM   2215 C  C   . SER A 1 334 ? 122.935 89.255  103.051 1.00 96.37 ? 322 SER A C   1 
ATOM   2216 O  O   . SER A 1 334 ? 121.937 89.609  103.664 1.00 96.37 ? 322 SER A O   1 
ATOM   2217 C  CB  . SER A 1 334 ? 124.010 91.255  101.990 1.00 96.37 ? 322 SER A CB  1 
ATOM   2218 O  OG  . SER A 1 334 ? 124.147 90.753  100.676 1.00 96.37 ? 322 SER A OG  1 
ATOM   2219 N  N   . TYR A 1 335 ? 122.996 88.101  102.390 1.00 97.28 ? 323 TYR A N   1 
ATOM   2220 C  CA  . TYR A 1 335 ? 121.844 87.211  102.314 1.00 97.28 ? 323 TYR A CA  1 
ATOM   2221 C  C   . TYR A 1 335 ? 121.392 86.736  103.677 1.00 97.28 ? 323 TYR A C   1 
ATOM   2222 O  O   . TYR A 1 335 ? 120.199 86.710  103.957 1.00 97.28 ? 323 TYR A O   1 
ATOM   2223 C  CB  . TYR A 1 335 ? 122.207 86.006  101.455 1.00 97.28 ? 323 TYR A CB  1 
ATOM   2224 C  CG  . TYR A 1 335 ? 121.045 85.123  101.068 1.00 97.28 ? 323 TYR A CG  1 
ATOM   2225 C  CD1 . TYR A 1 335 ? 119.815 85.664  100.731 1.00 97.28 ? 323 TYR A CD1 1 
ATOM   2226 C  CD2 . TYR A 1 335 ? 121.188 83.747  101.013 1.00 97.28 ? 323 TYR A CD2 1 
ATOM   2227 C  CE1 . TYR A 1 335 ? 118.757 84.859  100.369 1.00 97.28 ? 323 TYR A CE1 1 
ATOM   2228 C  CE2 . TYR A 1 335 ? 120.135 82.933  100.652 1.00 97.28 ? 323 TYR A CE2 1 
ATOM   2229 C  CZ  . TYR A 1 335 ? 118.921 83.495  100.330 1.00 97.28 ? 323 TYR A CZ  1 
ATOM   2230 O  OH  . TYR A 1 335 ? 117.868 82.687  99.968  1.00 97.28 ? 323 TYR A OH  1 
ATOM   2231 N  N   . ARG A 1 336 ? 122.335 86.383  104.536 1.00 96.95 ? 324 ARG A N   1 
ATOM   2232 C  CA  . ARG A 1 336 ? 121.998 85.936  105.875 1.00 96.95 ? 324 ARG A CA  1 
ATOM   2233 C  C   . ARG A 1 336 ? 121.341 87.061  106.648 1.00 96.95 ? 324 ARG A C   1 
ATOM   2234 O  O   . ARG A 1 336 ? 120.319 86.854  107.297 1.00 96.95 ? 324 ARG A O   1 
ATOM   2235 C  CB  . ARG A 1 336 ? 123.268 85.456  106.571 1.00 96.95 ? 324 ARG A CB  1 
ATOM   2236 C  CG  . ARG A 1 336 ? 123.353 85.703  108.067 1.00 96.95 ? 324 ARG A CG  1 
ATOM   2237 C  CD  . ARG A 1 336 ? 124.800 85.594  108.520 1.00 96.95 ? 324 ARG A CD  1 
ATOM   2238 N  NE  . ARG A 1 336 ? 125.674 86.465  107.735 1.00 96.95 ? 324 ARG A NE  1 
ATOM   2239 C  CZ  . ARG A 1 336 ? 126.150 87.632  108.158 1.00 96.95 ? 324 ARG A CZ  1 
ATOM   2240 N  NH1 . ARG A 1 336 ? 125.858 88.069  109.374 1.00 96.95 ? 324 ARG A NH1 1 
ATOM   2241 N  NH2 . ARG A 1 336 ? 126.933 88.355  107.370 1.00 96.95 ? 324 ARG A NH2 1 
ATOM   2242 N  N   . ASP A 1 337 ? 121.903 88.257  106.562 1.00 97.38 ? 325 ASP A N   1 
ATOM   2243 C  CA  . ASP A 1 337 ? 121.374 89.393  107.295 1.00 97.38 ? 325 ASP A CA  1 
ATOM   2244 C  C   . ASP A 1 337 ? 119.977 89.757  106.857 1.00 97.38 ? 325 ASP A C   1 
ATOM   2245 O  O   . ASP A 1 337 ? 119.130 90.050  107.684 1.00 97.38 ? 325 ASP A O   1 
ATOM   2246 C  CB  . ASP A 1 337 ? 122.295 90.596  107.155 1.00 97.38 ? 325 ASP A CB  1 
ATOM   2247 C  CG  . ASP A 1 337 ? 123.485 90.515  108.073 1.00 97.38 ? 325 ASP A CG  1 
ATOM   2248 O  OD1 . ASP A 1 337 ? 123.533 89.575  108.891 1.00 97.38 ? 325 ASP A OD1 1 
ATOM   2249 O  OD2 . ASP A 1 337 ? 124.362 91.395  107.985 1.00 97.38 ? 325 ASP A OD2 1 
ATOM   2250 N  N   . CYS A 1 338 ? 119.726 89.724  105.555 1.00 97.73 ? 326 CYS A N   1 
ATOM   2251 C  CA  . CYS A 1 338 ? 118.419 90.089  105.049 1.00 97.73 ? 326 CYS A CA  1 
ATOM   2252 C  C   . CYS A 1 338 ? 117.355 89.150  105.566 1.00 97.73 ? 326 CYS A C   1 
ATOM   2253 O  O   . CYS A 1 338 ? 116.280 89.580  105.963 1.00 97.73 ? 326 CYS A O   1 
ATOM   2254 C  CB  . CYS A 1 338 ? 118.410 90.083  103.527 1.00 97.73 ? 326 CYS A CB  1 
ATOM   2255 S  SG  . CYS A 1 338 ? 119.326 91.441  102.774 1.00 97.73 ? 326 CYS A SG  1 
ATOM   2256 N  N   . MET A 1 339 ? 117.654 87.860  105.578 1.00 97.29 ? 327 MET A N   1 
ATOM   2257 C  CA  . MET A 1 339 ? 116.693 86.912  106.088 1.00 97.29 ? 327 MET A CA  1 
ATOM   2258 C  C   . MET A 1 339 ? 116.412 87.121  107.568 1.00 97.29 ? 327 MET A C   1 
ATOM   2259 O  O   . MET A 1 339 ? 115.259 87.145  107.977 1.00 97.29 ? 327 MET A O   1 
ATOM   2260 C  CB  . MET A 1 339 ? 117.151 85.486  105.815 1.00 97.29 ? 327 MET A CB  1 
ATOM   2261 C  CG  . MET A 1 339 ? 117.315 85.160  104.339 1.00 97.29 ? 327 MET A CG  1 
ATOM   2262 S  SD  . MET A 1 339 ? 115.823 85.446  103.369 1.00 97.29 ? 327 MET A SD  1 
ATOM   2263 C  CE  . MET A 1 339 ? 116.282 86.889  102.410 1.00 97.29 ? 327 MET A CE  1 
ATOM   2264 N  N   . LEU A 1 340 ? 117.460 87.277  108.370 1.00 97.42 ? 328 LEU A N   1 
ATOM   2265 C  CA  . LEU A 1 340 ? 117.284 87.521  109.799 1.00 97.42 ? 328 LEU A CA  1 
ATOM   2266 C  C   . LEU A 1 340 ? 116.504 88.786  110.051 1.00 97.42 ? 328 LEU A C   1 
ATOM   2267 O  O   . LEU A 1 340 ? 115.485 88.755  110.723 1.00 97.42 ? 328 LEU A O   1 
ATOM   2268 C  CB  . LEU A 1 340 ? 118.632 87.614  110.508 1.00 97.42 ? 328 LEU A CB  1 
ATOM   2269 C  CG  . LEU A 1 340 ? 119.440 86.324  110.602 1.00 97.42 ? 328 LEU A CG  1 
ATOM   2270 C  CD1 . LEU A 1 340 ? 120.797 86.593  111.234 1.00 97.42 ? 328 LEU A CD1 1 
ATOM   2271 C  CD2 . LEU A 1 340 ? 118.670 85.277  111.390 1.00 97.42 ? 328 LEU A CD2 1 
ATOM   2272 N  N   . LEU A 1 341 ? 116.968 89.901  109.506 1.00 97.61 ? 329 LEU A N   1 
ATOM   2273 C  CA  . LEU A 1 341 ? 116.314 91.182  109.747 1.00 97.61 ? 329 LEU A CA  1 
ATOM   2274 C  C   . LEU A 1 341 ? 114.888 91.252  109.235 1.00 97.61 ? 329 LEU A C   1 
ATOM   2275 O  O   . LEU A 1 341 ? 114.024 91.799  109.905 1.00 97.61 ? 329 LEU A O   1 
ATOM   2276 C  CB  . LEU A 1 341 ? 117.131 92.316  109.142 1.00 97.61 ? 329 LEU A CB  1 
ATOM   2277 C  CG  . LEU A 1 341 ? 118.499 92.555  109.773 1.00 97.61 ? 329 LEU A CG  1 
ATOM   2278 C  CD1 . LEU A 1 341 ? 119.233 93.657  109.027 1.00 97.61 ? 329 LEU A CD1 1 
ATOM   2279 C  CD2 . LEU A 1 341 ? 118.354 92.886  111.250 1.00 97.61 ? 329 LEU A CD2 1 
ATOM   2280 N  N   . GLY A 1 342 ? 114.635 90.712  108.051 1.00 96.81 ? 330 GLY A N   1 
ATOM   2281 C  CA  . GLY A 1 342 ? 113.283 90.692  107.535 1.00 96.81 ? 330 GLY A CA  1 
ATOM   2282 C  C   . GLY A 1 342 ? 112.346 89.863  108.381 1.00 96.81 ? 330 GLY A C   1 
ATOM   2283 O  O   . GLY A 1 342 ? 111.234 90.286  108.671 1.00 96.81 ? 330 GLY A O   1 
ATOM   2284 N  N   . CYS A 1 343 ? 112.790 88.690  108.804 1.00 96.30 ? 331 CYS A N   1 
ATOM   2285 C  CA  . CYS A 1 343 ? 111.974 87.858  109.678 1.00 96.30 ? 331 CYS A CA  1 
ATOM   2286 C  C   . CYS A 1 343 ? 111.737 88.504  111.029 1.00 96.30 ? 331 CYS A C   1 
ATOM   2287 O  O   . CYS A 1 343 ? 110.654 88.399  111.579 1.00 96.30 ? 331 CYS A O   1 
ATOM   2288 C  CB  . CYS A 1 343 ? 112.584 86.468  109.833 1.00 96.30 ? 331 CYS A CB  1 
ATOM   2289 S  SG  . CYS A 1 343 ? 112.455 85.453  108.344 1.00 96.30 ? 331 CYS A SG  1 
ATOM   2290 N  N   . LEU A 1 344 ? 112.751 89.152  111.579 1.00 96.97 ? 332 LEU A N   1 
ATOM   2291 C  CA  . LEU A 1 344 ? 112.602 89.851  112.846 1.00 96.97 ? 332 LEU A CA  1 
ATOM   2292 C  C   . LEU A 1 344 ? 111.623 90.995  112.736 1.00 96.97 ? 332 LEU A C   1 
ATOM   2293 O  O   . LEU A 1 344 ? 110.840 91.220  113.645 1.00 96.97 ? 332 LEU A O   1 
ATOM   2294 C  CB  . LEU A 1 344 ? 113.949 90.376  113.324 1.00 96.97 ? 332 LEU A CB  1 
ATOM   2295 C  CG  . LEU A 1 344 ? 114.754 89.526  114.311 1.00 96.97 ? 332 LEU A CG  1 
ATOM   2296 C  CD1 . LEU A 1 344 ? 114.644 88.031  114.053 1.00 96.97 ? 332 LEU A CD1 1 
ATOM   2297 C  CD2 . LEU A 1 344 ? 116.207 89.965  114.319 1.00 96.97 ? 332 LEU A CD2 1 
ATOM   2298 N  N   . ASN A 1 345 ? 111.670 91.732  111.631 1.00 96.77 ? 333 ASN A N   1 
ATOM   2299 C  CA  . ASN A 1 345 ? 110.748 92.833  111.409 1.00 96.77 ? 333 ASN A CA  1 
ATOM   2300 C  C   . ASN A 1 345 ? 109.338 92.291  111.408 1.00 96.77 ? 333 ASN A C   1 
ATOM   2301 O  O   . ASN A 1 345 ? 108.480 92.775  112.135 1.00 96.77 ? 333 ASN A O   1 
ATOM   2302 C  CB  . ASN A 1 345 ? 111.042 93.464  110.055 1.00 96.77 ? 333 ASN A CB  1 
ATOM   2303 C  CG  . ASN A 1 345 ? 110.848 94.963  110.044 1.00 96.77 ? 333 ASN A CG  1 
ATOM   2304 O  OD1 . ASN A 1 345 ? 110.713 95.594  111.083 1.00 96.77 ? 333 ASN A OD1 1 
ATOM   2305 N  ND2 . ASN A 1 345 ? 110.858 95.544  108.855 1.00 96.77 ? 333 ASN A ND2 1 
ATOM   2306 N  N   . SER A 1 346 ? 109.091 91.282  110.586 1.00 96.59 ? 334 SER A N   1 
ATOM   2307 C  CA  . SER A 1 346 ? 107.772 90.679  110.511 1.00 96.59 ? 334 SER A CA  1 
ATOM   2308 C  C   . SER A 1 346 ? 107.361 90.027  111.812 1.00 96.59 ? 334 SER A C   1 
ATOM   2309 O  O   . SER A 1 346 ? 106.200 90.089  112.193 1.00 96.59 ? 334 SER A O   1 
ATOM   2310 C  CB  . SER A 1 346 ? 107.705 89.687  109.362 1.00 96.59 ? 334 SER A CB  1 
ATOM   2311 O  OG  . SER A 1 346 ? 107.631 90.363  108.124 1.00 96.59 ? 334 SER A OG  1 
ATOM   2312 N  N   . GLY A 1 347 ? 108.310 89.422  112.510 1.00 96.51 ? 335 GLY A N   1 
ATOM   2313 C  CA  . GLY A 1 347 ? 108.024 88.810  113.791 1.00 96.51 ? 335 GLY A CA  1 
ATOM   2314 C  C   . GLY A 1 347 ? 107.587 89.835  114.799 1.00 96.51 ? 335 GLY A C   1 
ATOM   2315 O  O   . GLY A 1 347 ? 106.678 89.583  115.573 1.00 96.51 ? 335 GLY A O   1 
ATOM   2316 N  N   . THR A 1 348 ? 108.226 90.998  114.791 1.00 96.72 ? 336 THR A N   1 
ATOM   2317 C  CA  . THR A 1 348 ? 107.862 92.076  115.701 1.00 96.72 ? 336 THR A CA  1 
ATOM   2318 C  C   . THR A 1 348 ? 106.440 92.518  115.443 1.00 96.72 ? 336 THR A C   1 
ATOM   2319 O  O   . THR A 1 348 ? 105.668 92.678  116.373 1.00 96.72 ? 336 THR A O   1 
ATOM   2320 C  CB  . THR A 1 348 ? 108.797 93.283  115.541 1.00 96.72 ? 336 THR A CB  1 
ATOM   2321 O  OG1 . THR A 1 348 ? 110.157 92.863  115.699 1.00 96.72 ? 336 THR A OG1 1 
ATOM   2322 C  CG2 . THR A 1 348 ? 108.485 94.351  116.572 1.00 96.72 ? 336 THR A CG2 1 
ATOM   2323 N  N   . SER A 1 349 ? 106.079 92.692  114.180 1.00 96.39 ? 337 SER A N   1 
ATOM   2324 C  CA  . SER A 1 349 ? 104.724 93.092  113.833 1.00 96.39 ? 337 SER A CA  1 
ATOM   2325 C  C   . SER A 1 349 ? 103.725 92.041  114.255 1.00 96.39 ? 337 SER A C   1 
ATOM   2326 O  O   . SER A 1 349 ? 102.678 92.366  114.796 1.00 96.39 ? 337 SER A O   1 
ATOM   2327 C  CB  . SER A 1 349 ? 104.611 93.301  112.331 1.00 96.39 ? 337 SER A CB  1 
ATOM   2328 O  OG  . SER A 1 349 ? 105.408 94.379  111.896 1.00 96.39 ? 337 SER A OG  1 
ATOM   2329 N  N   . PHE A 1 350 ? 104.052 90.780  114.032 1.00 96.65 ? 338 PHE A N   1 
ATOM   2330 C  CA  . PHE A 1 350 ? 103.164 89.691  114.394 1.00 96.65 ? 338 PHE A CA  1 
ATOM   2331 C  C   . PHE A 1 350 ? 102.937 89.622  115.895 1.00 96.65 ? 338 PHE A C   1 
ATOM   2332 O  O   . PHE A 1 350 ? 101.811 89.425  116.337 1.00 96.65 ? 338 PHE A O   1 
ATOM   2333 C  CB  . PHE A 1 350 ? 103.752 88.378  113.887 1.00 96.65 ? 338 PHE A CB  1 
ATOM   2334 C  CG  . PHE A 1 350 ? 102.832 87.203  114.016 1.00 96.65 ? 338 PHE A CG  1 
ATOM   2335 C  CD1 . PHE A 1 350 ? 101.612 87.188  113.367 1.00 96.65 ? 338 PHE A CD1 1 
ATOM   2336 C  CD2 . PHE A 1 350 ? 103.202 86.101  114.763 1.00 96.65 ? 338 PHE A CD2 1 
ATOM   2337 C  CE1 . PHE A 1 350 ? 100.766 86.105  113.480 1.00 96.65 ? 338 PHE A CE1 1 
ATOM   2338 C  CE2 . PHE A 1 350 ? 102.363 85.012  114.876 1.00 96.65 ? 338 PHE A CE2 1 
ATOM   2339 C  CZ  . PHE A 1 350 ? 101.143 85.014  114.234 1.00 96.65 ? 338 PHE A CZ  1 
ATOM   2340 N  N   . VAL A 1 351 ? 103.995 89.784  116.683 1.00 96.73 ? 339 VAL A N   1 
ATOM   2341 C  CA  . VAL A 1 351 ? 103.881 89.708  118.136 1.00 96.73 ? 339 VAL A CA  1 
ATOM   2342 C  C   . VAL A 1 351 ? 103.183 90.942  118.681 1.00 96.73 ? 339 VAL A C   1 
ATOM   2343 O  O   . VAL A 1 351 ? 102.339 90.835  119.565 1.00 96.73 ? 339 VAL A O   1 
ATOM   2344 C  CB  . VAL A 1 351 ? 105.260 89.507  118.792 1.00 96.73 ? 339 VAL A CB  1 
ATOM   2345 C  CG1 . VAL A 1 351 ? 105.201 89.738  120.293 1.00 96.73 ? 339 VAL A CG1 1 
ATOM   2346 C  CG2 . VAL A 1 351 ? 105.788 88.115  118.490 1.00 96.73 ? 339 VAL A CG2 1 
ATOM   2347 N  N   . SER A 1 352 ? 103.513 92.113  118.153 1.00 94.78 ? 340 SER A N   1 
ATOM   2348 C  CA  . SER A 1 352 ? 102.854 93.342  118.568 1.00 94.78 ? 340 SER A CA  1 
ATOM   2349 C  C   . SER A 1 352 ? 101.368 93.191  118.348 1.00 94.78 ? 340 SER A C   1 
ATOM   2350 O  O   . SER A 1 352 ? 100.570 93.719  119.117 1.00 94.78 ? 340 SER A O   1 
ATOM   2351 C  CB  . SER A 1 352 ? 103.372 94.530  117.764 1.00 94.78 ? 340 SER A CB  1 
ATOM   2352 O  OG  . SER A 1 352 ? 104.755 94.735  117.976 1.00 94.78 ? 340 SER A OG  1 
ATOM   2353 N  N   . GLY A 1 353 ? 100.987 92.494  117.283 1.00 94.46 ? 341 GLY A N   1 
ATOM   2354 C  CA  . GLY A 1 353 ? 99.586  92.276  116.990 1.00 94.46 ? 341 GLY A CA  1 
ATOM   2355 C  C   . GLY A 1 353 ? 98.884  91.524  118.094 1.00 94.46 ? 341 GLY A C   1 
ATOM   2356 O  O   . GLY A 1 353 ? 97.754  91.833  118.417 1.00 94.46 ? 341 GLY A O   1 
ATOM   2357 N  N   . PHE A 1 354 ? 99.548  90.550  118.699 1.00 96.39 ? 342 PHE A N   1 
ATOM   2358 C  CA  . PHE A 1 354 ? 98.956  89.821  119.812 1.00 96.39 ? 342 PHE A CA  1 
ATOM   2359 C  C   . PHE A 1 354 ? 98.609  90.761  120.940 1.00 96.39 ? 342 PHE A C   1 
ATOM   2360 O  O   . PHE A 1 354 ? 97.544  90.650  121.529 1.00 96.39 ? 342 PHE A O   1 
ATOM   2361 C  CB  . PHE A 1 354 ? 99.894  88.740  120.340 1.00 96.39 ? 342 PHE A CB  1 
ATOM   2362 C  CG  . PHE A 1 354 ? 99.908  87.492  119.520 1.00 96.39 ? 342 PHE A CG  1 
ATOM   2363 C  CD1 . PHE A 1 354 ? 98.890  86.568  119.635 1.00 96.39 ? 342 PHE A CD1 1 
ATOM   2364 C  CD2 . PHE A 1 354 ? 100.948 87.234  118.652 1.00 96.39 ? 342 PHE A CD2 1 
ATOM   2365 C  CE1 . PHE A 1 354 ? 98.902  85.412  118.886 1.00 96.39 ? 342 PHE A CE1 1 
ATOM   2366 C  CE2 . PHE A 1 354 ? 100.967 86.082  117.900 1.00 96.39 ? 342 PHE A CE2 1 
ATOM   2367 C  CZ  . PHE A 1 354 ? 99.943  85.168  118.016 1.00 96.39 ? 342 PHE A CZ  1 
ATOM   2368 N  N   . ALA A 1 355 ? 99.528  91.661  121.272 1.00 93.17 ? 343 ALA A N   1 
ATOM   2369 C  CA  . ALA A 1 355 ? 99.302  92.629  122.344 1.00 93.17 ? 343 ALA A CA  1 
ATOM   2370 C  C   . ALA A 1 355 ? 98.114  93.501  122.049 1.00 93.17 ? 343 ALA A C   1 
ATOM   2371 O  O   . ALA A 1 355 ? 97.215  93.619  122.862 1.00 93.17 ? 343 ALA A O   1 
ATOM   2372 C  CB  . ALA A 1 355 ? 100.526 93.500  122.532 1.00 93.17 ? 343 ALA A CB  1 
ATOM   2373 N  N   . ILE A 1 356 ? 98.102  94.116  120.877 1.00 90.75 ? 344 ILE A N   1 
ATOM   2374 C  CA  . ILE A 1 356 ? 97.021  95.022  120.534 1.00 90.75 ? 344 ILE A CA  1 
ATOM   2375 C  C   . ILE A 1 356 ? 95.674  94.310  120.468 1.00 90.75 ? 344 ILE A C   1 
ATOM   2376 O  O   . ILE A 1 356 ? 94.672  94.857  120.902 1.00 90.75 ? 344 ILE A O   1 
ATOM   2377 C  CB  . ILE A 1 356 ? 97.351  95.880  119.284 1.00 90.75 ? 344 ILE A CB  1 
ATOM   2378 C  CG1 . ILE A 1 356 ? 96.471  97.123  119.221 1.00 90.75 ? 344 ILE A CG1 1 
ATOM   2379 C  CG2 . ILE A 1 356 ? 97.242  95.082  118.000 1.00 90.75 ? 344 ILE A CG2 1 
ATOM   2380 C  CD1 . ILE A 1 356 ? 97.088  98.253  118.430 1.00 90.75 ? 344 ILE A CD1 1 
ATOM   2381 N  N   . PHE A 1 357 ? 95.645  93.088  119.952 1.00 92.56 ? 345 PHE A N   1 
ATOM   2382 C  CA  . PHE A 1 357 ? 94.387  92.367  119.818 1.00 92.56 ? 345 PHE A CA  1 
ATOM   2383 C  C   . PHE A 1 357 ? 93.885  91.825  121.139 1.00 92.56 ? 345 PHE A C   1 
ATOM   2384 O  O   . PHE A 1 357 ? 92.682  91.763  121.346 1.00 92.56 ? 345 PHE A O   1 
ATOM   2385 C  CB  . PHE A 1 357 ? 94.460  91.322  118.716 1.00 92.56 ? 345 PHE A CB  1 
ATOM   2386 C  CG  . PHE A 1 357 ? 94.259  91.897  117.341 1.00 92.56 ? 345 PHE A CG  1 
ATOM   2387 C  CD1 . PHE A 1 357 ? 95.318  92.438  116.637 1.00 92.56 ? 345 PHE A CD1 1 
ATOM   2388 C  CD2 . PHE A 1 357 ? 93.007  91.919  116.763 1.00 92.56 ? 345 PHE A CD2 1 
ATOM   2389 C  CE1 . PHE A 1 357 ? 95.139  92.978  115.381 1.00 92.56 ? 345 PHE A CE1 1 
ATOM   2390 C  CE2 . PHE A 1 357 ? 92.821  92.455  115.504 1.00 92.56 ? 345 PHE A CE2 1 
ATOM   2391 C  CZ  . PHE A 1 357 ? 93.887  92.985  114.812 1.00 92.56 ? 345 PHE A CZ  1 
ATOM   2392 N  N   . SER A 1 358 ? 94.776  91.437  122.039 1.00 94.36 ? 346 SER A N   1 
ATOM   2393 C  CA  . SER A 1 358 ? 94.354  91.042  123.370 1.00 94.36 ? 346 SER A CA  1 
ATOM   2394 C  C   . SER A 1 358 ? 93.705  92.214  124.096 1.00 94.36 ? 346 SER A C   1 
ATOM   2395 O  O   . SER A 1 358 ? 92.728  92.023  124.813 1.00 94.36 ? 346 SER A O   1 
ATOM   2396 C  CB  . SER A 1 358 ? 95.534  90.492  124.150 1.00 94.36 ? 346 SER A CB  1 
ATOM   2397 O  OG  . SER A 1 358 ? 96.616  91.397  124.142 1.00 94.36 ? 346 SER A OG  1 
ATOM   2398 N  N   . ILE A 1 359 ? 94.232  93.424  123.920 1.00 90.52 ? 347 ILE A N   1 
ATOM   2399 C  CA  . ILE A 1 359 ? 93.618  94.615  124.513 1.00 90.52 ? 347 ILE A CA  1 
ATOM   2400 C  C   . ILE A 1 359 ? 92.274  94.881  123.869 1.00 90.52 ? 347 ILE A C   1 
ATOM   2401 O  O   . ILE A 1 359 ? 91.319  95.204  124.550 1.00 90.52 ? 347 ILE A O   1 
ATOM   2402 C  CB  . ILE A 1 359 ? 94.505  95.864  124.342 1.00 90.52 ? 347 ILE A CB  1 
ATOM   2403 C  CG1 . ILE A 1 359 ? 95.889  95.632  124.941 1.00 90.52 ? 347 ILE A CG1 1 
ATOM   2404 C  CG2 . ILE A 1 359 ? 93.873  97.079  125.003 1.00 90.52 ? 347 ILE A CG2 1 
ATOM   2405 C  CD1 . ILE A 1 359 ? 96.934  96.592  124.421 1.00 90.52 ? 347 ILE A CD1 1 
ATOM   2406 N  N   . LEU A 1 360 ? 92.191  94.746  122.550 1.00 89.48 ? 348 LEU A N   1 
ATOM   2407 C  CA  . LEU A 1 360 ? 90.931  94.960  121.844 1.00 89.48 ? 348 LEU A CA  1 
ATOM   2408 C  C   . LEU A 1 360 ? 89.894  93.959  122.295 1.00 89.48 ? 348 LEU A C   1 
ATOM   2409 O  O   . LEU A 1 360 ? 88.725  94.295  122.397 1.00 89.48 ? 348 LEU A O   1 
ATOM   2410 C  CB  . LEU A 1 360 ? 91.120  94.894  120.332 1.00 89.48 ? 348 LEU A CB  1 
ATOM   2411 C  CG  . LEU A 1 360 ? 91.919  96.012  119.675 1.00 89.48 ? 348 LEU A CG  1 
ATOM   2412 C  CD1 . LEU A 1 360 ? 91.972  95.787  118.175 1.00 89.48 ? 348 LEU A CD1 1 
ATOM   2413 C  CD2 . LEU A 1 360 ? 91.307  97.362  120.000 1.00 89.48 ? 348 LEU A CD2 1 
ATOM   2414 N  N   . GLY A 1 361 ? 90.306  92.725  122.555 1.00 92.61 ? 349 GLY A N   1 
ATOM   2415 C  CA  . GLY A 1 361 ? 89.386  91.736  123.084 1.00 92.61 ? 349 GLY A CA  1 
ATOM   2416 C  C   . GLY A 1 361 ? 88.888  92.135  124.453 1.00 92.61 ? 349 GLY A C   1 
ATOM   2417 O  O   . GLY A 1 361 ? 87.709  91.974  124.752 1.00 92.61 ? 349 GLY A O   1 
ATOM   2418 N  N   . PHE A 1 362 ? 89.775  92.654  125.294 1.00 90.04 ? 350 PHE A N   1 
ATOM   2419 C  CA  . PHE A 1 362 ? 89.368  93.137  126.604 1.00 90.04 ? 350 PHE A CA  1 
ATOM   2420 C  C   . PHE A 1 362 ? 88.404  94.294  126.493 1.00 90.04 ? 350 PHE A C   1 
ATOM   2421 O  O   . PHE A 1 362 ? 87.400  94.344  127.191 1.00 90.04 ? 350 PHE A O   1 
ATOM   2422 C  CB  . PHE A 1 362 ? 90.605  93.600  127.370 1.00 90.04 ? 350 PHE A CB  1 
ATOM   2423 C  CG  . PHE A 1 362 ? 90.300  94.418  128.592 1.00 90.04 ? 350 PHE A CG  1 
ATOM   2424 C  CD1 . PHE A 1 362 ? 89.822  93.819  129.741 1.00 90.04 ? 350 PHE A CD1 1 
ATOM   2425 C  CD2 . PHE A 1 362 ? 90.519  95.784  128.597 1.00 90.04 ? 350 PHE A CD2 1 
ATOM   2426 C  CE1 . PHE A 1 362 ? 89.547  94.565  130.867 1.00 90.04 ? 350 PHE A CE1 1 
ATOM   2427 C  CE2 . PHE A 1 362 ? 90.246  96.536  129.718 1.00 90.04 ? 350 PHE A CE2 1 
ATOM   2428 C  CZ  . PHE A 1 362 ? 89.762  95.926  130.856 1.00 90.04 ? 350 PHE A CZ  1 
ATOM   2429 N  N   . MET A 1 363 ? 88.700  95.229  125.604 1.00 87.27 ? 351 MET A N   1 
ATOM   2430 C  CA  . MET A 1 363 ? 87.848  96.380  125.442 1.00 87.27 ? 351 MET A CA  1 
ATOM   2431 C  C   . MET A 1 363 ? 86.493  95.932  124.944 1.00 87.27 ? 351 MET A C   1 
ATOM   2432 O  O   . MET A 1 363 ? 85.476  96.432  125.393 1.00 87.27 ? 351 MET A O   1 
ATOM   2433 C  CB  . MET A 1 363 ? 88.486  97.379  124.489 1.00 87.27 ? 351 MET A CB  1 
ATOM   2434 C  CG  . MET A 1 363 ? 89.753  98.038  124.998 1.00 87.27 ? 351 MET A CG  1 
ATOM   2435 S  SD  . MET A 1 363 ? 90.582  98.958  123.687 1.00 87.27 ? 351 MET A SD  1 
ATOM   2436 C  CE  . MET A 1 363 ? 89.308  100.129 123.235 1.00 87.27 ? 351 MET A CE  1 
ATOM   2437 N  N   . ALA A 1 364 ? 86.470  94.970  124.031 1.00 87.99 ? 352 ALA A N   1 
ATOM   2438 C  CA  . ALA A 1 364 ? 85.213  94.505  123.465 1.00 87.99 ? 352 ALA A CA  1 
ATOM   2439 C  C   . ALA A 1 364 ? 84.316  93.900  124.517 1.00 87.99 ? 352 ALA A C   1 
ATOM   2440 O  O   . ALA A 1 364 ? 83.113  94.112  124.501 1.00 87.99 ? 352 ALA A O   1 
ATOM   2441 C  CB  . ALA A 1 364 ? 85.469  93.500  122.367 1.00 87.99 ? 352 ALA A CB  1 
ATOM   2442 N  N   . GLN A 1 365 ? 84.894  93.138  125.433 1.00 88.30 ? 353 GLN A N   1 
ATOM   2443 C  CA  . GLN A 1 365 ? 84.101  92.544  126.492 1.00 88.30 ? 353 GLN A CA  1 
ATOM   2444 C  C   . GLN A 1 365 ? 83.773  93.525  127.618 1.00 88.30 ? 353 GLN A C   1 
ATOM   2445 O  O   . GLN A 1 365 ? 82.802  93.308  128.342 1.00 88.30 ? 353 GLN A O   1 
ATOM   2446 C  CB  . GLN A 1 365 ? 84.744  91.258  127.028 1.00 88.30 ? 353 GLN A CB  1 
ATOM   2447 C  CG  . GLN A 1 365 ? 86.091  91.426  127.707 1.00 88.30 ? 353 GLN A CG  1 
ATOM   2448 C  CD  . GLN A 1 365 ? 85.981  91.616  129.206 1.00 88.30 ? 353 GLN A CD  1 
ATOM   2449 O  OE1 . GLN A 1 365 ? 84.986  91.237  129.822 1.00 88.30 ? 353 GLN A OE1 1 
ATOM   2450 N  NE2 . GLN A 1 365 ? 87.008  92.200  129.801 1.00 88.30 ? 353 GLN A NE2 1 
ATOM   2451 N  N   . GLU A 1 366 ? 84.558  94.572  127.815 1.00 83.63 ? 354 GLU A N   1 
ATOM   2452 C  CA  . GLU A 1 366 ? 84.198  95.529  128.843 1.00 83.63 ? 354 GLU A CA  1 
ATOM   2453 C  C   . GLU A 1 366 ? 83.034  96.322  128.302 1.00 83.63 ? 354 GLU A C   1 
ATOM   2454 O  O   . GLU A 1 366 ? 81.983  96.398  128.925 1.00 83.63 ? 354 GLU A O   1 
ATOM   2455 C  CB  . GLU A 1 366 ? 85.376  96.436  129.165 1.00 83.63 ? 354 GLU A CB  1 
ATOM   2456 C  CG  . GLU A 1 366 ? 85.276  97.134  130.508 1.00 83.63 ? 354 GLU A CG  1 
ATOM   2457 C  CD  . GLU A 1 366 ? 86.485  97.998  130.788 1.00 83.63 ? 354 GLU A CD  1 
ATOM   2458 O  OE1 . GLU A 1 366 ? 86.630  98.476  131.932 1.00 83.63 ? 354 GLU A OE1 1 
ATOM   2459 O  OE2 . GLU A 1 366 ? 87.293  98.196  129.858 1.00 83.63 ? 354 GLU A OE2 1 
ATOM   2460 N  N   . GLN A 1 367 ? 83.213  96.909  127.131 1.00 81.43 ? 355 GLN A N   1 
ATOM   2461 C  CA  . GLN A 1 367 ? 82.153  97.681  126.497 1.00 81.43 ? 355 GLN A CA  1 
ATOM   2462 C  C   . GLN A 1 367 ? 80.936  96.846  126.111 1.00 81.43 ? 355 GLN A C   1 
ATOM   2463 O  O   . GLN A 1 367 ? 79.808  97.318  126.212 1.00 81.43 ? 355 GLN A O   1 
ATOM   2464 C  CB  . GLN A 1 367 ? 82.722  98.451  125.309 1.00 81.43 ? 355 GLN A CB  1 
ATOM   2465 C  CG  . GLN A 1 367 ? 83.877  99.356  125.706 1.00 81.43 ? 355 GLN A CG  1 
ATOM   2466 C  CD  . GLN A 1 367 ? 84.491  100.084 124.532 1.00 81.43 ? 355 GLN A CD  1 
ATOM   2467 O  OE1 . GLN A 1 367 ? 85.616  100.574 124.613 1.00 81.43 ? 355 GLN A OE1 1 
ATOM   2468 N  NE2 . GLN A 1 367 ? 83.758  100.153 123.429 1.00 81.43 ? 355 GLN A NE2 1 
ATOM   2469 N  N   . GLY A 1 368 ? 81.143  95.603  125.698 1.00 81.31 ? 356 GLY A N   1 
ATOM   2470 C  CA  . GLY A 1 368 ? 80.031  94.738  125.340 1.00 81.31 ? 356 GLY A CA  1 
ATOM   2471 C  C   . GLY A 1 368 ? 79.685  94.865  123.874 1.00 81.31 ? 356 GLY A C   1 
ATOM   2472 O  O   . GLY A 1 368 ? 78.519  94.846  123.486 1.00 81.31 ? 356 GLY A O   1 
ATOM   2473 N  N   . VAL A 1 369 ? 80.720  94.992  123.056 1.00 83.01 ? 357 VAL A N   1 
ATOM   2474 C  CA  . VAL A 1 369 ? 80.582  95.317  121.647 1.00 83.01 ? 357 VAL A CA  1 
ATOM   2475 C  C   . VAL A 1 369 ? 81.487  94.362  120.878 1.00 83.01 ? 357 VAL A C   1 
ATOM   2476 O  O   . VAL A 1 369 ? 82.355  93.731  121.466 1.00 83.01 ? 357 VAL A O   1 
ATOM   2477 C  CB  . VAL A 1 369 ? 80.942  96.793  121.391 1.00 83.01 ? 357 VAL A CB  1 
ATOM   2478 C  CG1 . VAL A 1 369 ? 82.426  97.035  121.585 1.00 83.01 ? 357 VAL A CG1 1 
ATOM   2479 C  CG2 . VAL A 1 369 ? 80.471  97.259  120.022 1.00 83.01 ? 357 VAL A CG2 1 
ATOM   2480 N  N   . ASP A 1 370 ? 81.248  94.191  119.586 1.00 85.48 ? 358 ASP A N   1 
ATOM   2481 C  CA  . ASP A 1 370 ? 82.108  93.348  118.771 1.00 85.48 ? 358 ASP A CA  1 
ATOM   2482 C  C   . ASP A 1 370 ? 83.535  93.860  118.701 1.00 85.48 ? 358 ASP A C   1 
ATOM   2483 O  O   . ASP A 1 370 ? 83.754  95.063  118.687 1.00 85.48 ? 358 ASP A O   1 
ATOM   2484 C  CB  . ASP A 1 370 ? 81.546  93.219  117.359 1.00 85.48 ? 358 ASP A CB  1 
ATOM   2485 C  CG  . ASP A 1 370 ? 80.139  92.657  117.340 1.00 85.48 ? 358 ASP A CG  1 
ATOM   2486 O  OD1 . ASP A 1 370 ? 79.698  92.108  118.371 1.00 85.48 ? 358 ASP A OD1 1 
ATOM   2487 O  OD2 . ASP A 1 370 ? 79.474  92.760  116.288 1.00 85.48 ? 358 ASP A OD2 1 
ATOM   2488 N  N   . ILE A 1 371 ? 84.505  92.954  118.668 1.00 84.36 ? 359 ILE A N   1 
ATOM   2489 C  CA  . ILE A 1 371 ? 85.908  93.324  118.557 1.00 84.36 ? 359 ILE A CA  1 
ATOM   2490 C  C   . ILE A 1 371 ? 86.090  94.174  117.323 1.00 84.36 ? 359 ILE A C   1 
ATOM   2491 O  O   . ILE A 1 371 ? 86.858  95.119  117.333 1.00 84.36 ? 359 ILE A O   1 
ATOM   2492 C  CB  . ILE A 1 371 ? 86.825  92.093  118.498 1.00 84.36 ? 359 ILE A CB  1 
ATOM   2493 C  CG1 . ILE A 1 371 ? 86.467  91.121  119.616 1.00 84.36 ? 359 ILE A CG1 1 
ATOM   2494 C  CG2 . ILE A 1 371 ? 88.288  92.496  118.604 1.00 84.36 ? 359 ILE A CG2 1 
ATOM   2495 C  CD1 . ILE A 1 371 ? 87.403  89.944  119.708 1.00 84.36 ? 359 ILE A CD1 1 
ATOM   2496 N  N   . ALA A 1 372 ? 85.347  93.870  116.271 1.00 81.38 ? 360 ALA A N   1 
ATOM   2497 C  CA  . ALA A 1 372 ? 85.458  94.626  115.035 1.00 81.38 ? 360 ALA A CA  1 
ATOM   2498 C  C   . ALA A 1 372 ? 84.986  96.060  115.207 1.00 81.38 ? 360 ALA A C   1 
ATOM   2499 O  O   . ALA A 1 372 ? 85.504  96.969  114.562 1.00 81.38 ? 360 ALA A O   1 
ATOM   2500 C  CB  . ALA A 1 372 ? 84.681  93.941  113.930 1.00 81.38 ? 360 ALA A CB  1 
ATOM   2501 N  N   . ASP A 1 373 ? 83.995  96.270  116.061 1.00 77.78 ? 361 ASP A N   1 
ATOM   2502 C  CA  . ASP A 1 373 ? 83.457  97.609  116.267 1.00 77.78 ? 361 ASP A CA  1 
ATOM   2503 C  C   . ASP A 1 373 ? 84.021  98.356  117.465 1.00 77.78 ? 361 ASP A C   1 
ATOM   2504 O  O   . ASP A 1 373 ? 83.677  99.512  117.679 1.00 77.78 ? 361 ASP A O   1 
ATOM   2505 C  CB  . ASP A 1 373 ? 81.939  97.521  116.399 1.00 77.78 ? 361 ASP A CB  1 
ATOM   2506 C  CG  . ASP A 1 373 ? 81.281  96.925  115.175 1.00 77.78 ? 361 ASP A CG  1 
ATOM   2507 O  OD1 . ASP A 1 373 ? 81.879  96.998  114.081 1.00 77.78 ? 361 ASP A OD1 1 
ATOM   2508 O  OD2 . ASP A 1 373 ? 80.161  96.391  115.303 1.00 77.78 ? 361 ASP A OD2 1 
ATOM   2509 N  N   . VAL A 1 374 ? 84.868  97.713  118.257 1.00 75.80 ? 362 VAL A N   1 
ATOM   2510 C  CA  . VAL A 1 374 ? 85.380  98.341  119.478 1.00 75.80 ? 362 VAL A CA  1 
ATOM   2511 C  C   . VAL A 1 374 ? 86.264  99.570  119.273 1.00 75.80 ? 362 VAL A C   1 
ATOM   2512 O  O   . VAL A 1 374 ? 86.158  100.538 120.020 1.00 75.80 ? 362 VAL A O   1 
ATOM   2513 C  CB  . VAL A 1 374 ? 86.029  97.313  120.437 1.00 75.80 ? 362 VAL A CB  1 
ATOM   2514 C  CG1 . VAL A 1 374 ? 87.430  96.924  119.999 1.00 75.80 ? 362 VAL A CG1 1 
ATOM   2515 C  CG2 . VAL A 1 374 ? 86.042  97.855  121.851 1.00 75.80 ? 362 VAL A CG2 1 
ATOM   2516 N  N   . ALA A 1 375 ? 87.119  99.553  118.262 1.00 66.23 ? 363 ALA A N   1 
ATOM   2517 C  CA  . ALA A 1 375 ? 88.053  100.649 118.051 1.00 66.23 ? 363 ALA A CA  1 
ATOM   2518 C  C   . ALA A 1 375 ? 88.091  101.034 116.595 1.00 66.23 ? 363 ALA A C   1 
ATOM   2519 O  O   . ALA A 1 375 ? 87.462  100.384 115.765 1.00 66.23 ? 363 ALA A O   1 
ATOM   2520 C  CB  . ALA A 1 375 ? 89.431  100.283 118.549 1.00 66.23 ? 363 ALA A CB  1 
ATOM   2521 N  N   . GLU A 1 376 ? 88.783  102.116 116.277 1.00 62.43 ? 364 GLU A N   1 
ATOM   2522 C  CA  . GLU A 1 376 ? 88.811  102.604 114.908 1.00 62.43 ? 364 GLU A CA  1 
ATOM   2523 C  C   . GLU A 1 376 ? 89.415  101.653 113.909 1.00 62.43 ? 364 GLU A C   1 
ATOM   2524 O  O   . GLU A 1 376 ? 90.511  101.148 114.130 1.00 62.43 ? 364 GLU A O   1 
ATOM   2525 C  CB  . GLU A 1 376 ? 89.646  103.881 114.898 1.00 62.43 ? 364 GLU A CB  1 
ATOM   2526 C  CG  . GLU A 1 376 ? 89.665  104.646 113.596 1.00 62.43 ? 364 GLU A CG  1 
ATOM   2527 C  CD  . GLU A 1 376 ? 90.599  105.826 113.668 1.00 62.43 ? 364 GLU A CD  1 
ATOM   2528 O  OE1 . GLU A 1 376 ? 90.724  106.550 112.667 1.00 62.43 ? 364 GLU A OE1 1 
ATOM   2529 O  OE2 . GLU A 1 376 ? 91.215  106.022 114.732 1.00 62.43 ? 364 GLU A OE2 1 
ATOM   2530 N  N   . SER A 1 377 ? 88.731  101.415 112.792 1.00 54.93 ? 365 SER A N   1 
ATOM   2531 C  CA  . SER A 1 377 ? 89.306  100.605 111.727 1.00 54.93 ? 365 SER A CA  1 
ATOM   2532 C  C   . SER A 1 377 ? 90.028  101.580 110.851 1.00 54.93 ? 365 SER A C   1 
ATOM   2533 O  O   . SER A 1 377 ? 89.691  101.732 109.686 1.00 54.93 ? 365 SER A O   1 
ATOM   2534 C  CB  . SER A 1 377 ? 88.214  99.914  110.927 1.00 54.93 ? 365 SER A CB  1 
ATOM   2535 O  OG  . SER A 1 377 ? 87.555  98.932  111.704 1.00 54.93 ? 365 SER A OG  1 
ATOM   2536 N  N   . GLY A 1 378 ? 91.025  102.250 111.396 1.00 61.11 ? 366 GLY A N   1 
ATOM   2537 C  CA  . GLY A 1 378 ? 91.708  103.282 110.654 1.00 61.11 ? 366 GLY A CA  1 
ATOM   2538 C  C   . GLY A 1 378 ? 92.972  103.621 111.392 1.00 61.11 ? 366 GLY A C   1 
ATOM   2539 O  O   . GLY A 1 378 ? 93.237  103.064 112.452 1.00 61.11 ? 366 GLY A O   1 
ATOM   2540 N  N   . PRO A 1 379 ? 93.762  104.540 110.835 1.00 63.48 ? 367 PRO A N   1 
ATOM   2541 C  CA  . PRO A 1 379 ? 94.994  104.946 111.500 1.00 63.48 ? 367 PRO A CA  1 
ATOM   2542 C  C   . PRO A 1 379 ? 94.589  105.534 112.822 1.00 63.48 ? 367 PRO A C   1 
ATOM   2543 O  O   . PRO A 1 379 ? 93.607  106.259 112.880 1.00 63.48 ? 367 PRO A O   1 
ATOM   2544 C  CB  . PRO A 1 379 ? 95.558  106.015 110.569 1.00 63.48 ? 367 PRO A CB  1 
ATOM   2545 C  CG  . PRO A 1 379 ? 94.865  105.826 109.265 1.00 63.48 ? 367 PRO A CG  1 
ATOM   2546 C  CD  . PRO A 1 379 ? 93.503  105.325 109.619 1.00 63.48 ? 367 PRO A CD  1 
ATOM   2547 N  N   . GLY A 1 380 ? 95.250  105.186 113.907 1.00 70.85 ? 368 GLY A N   1 
ATOM   2548 C  CA  . GLY A 1 380 ? 94.781  105.677 115.185 1.00 70.85 ? 368 GLY A CA  1 
ATOM   2549 C  C   . GLY A 1 380 ? 94.287  104.579 116.077 1.00 70.85 ? 368 GLY A C   1 
ATOM   2550 O  O   . GLY A 1 380 ? 93.837  104.856 117.177 1.00 70.85 ? 368 GLY A O   1 
ATOM   2551 N  N   . LEU A 1 381 ? 94.327  103.337 115.606 1.00 74.66 ? 369 LEU A N   1 
ATOM   2552 C  CA  . LEU A 1 381 ? 93.978  102.203 116.445 1.00 74.66 ? 369 LEU A CA  1 
ATOM   2553 C  C   . LEU A 1 381 ? 94.983  102.092 117.572 1.00 74.66 ? 369 LEU A C   1 
ATOM   2554 O  O   . LEU A 1 381 ? 94.615  101.821 118.705 1.00 74.66 ? 369 LEU A O   1 
ATOM   2555 C  CB  . LEU A 1 381 ? 93.999  100.926 115.616 1.00 74.66 ? 369 LEU A CB  1 
ATOM   2556 C  CG  . LEU A 1 381 ? 93.841  99.600  116.360 1.00 74.66 ? 369 LEU A CG  1 
ATOM   2557 C  CD1 . LEU A 1 381 ? 92.421  99.448  116.864 1.00 74.66 ? 369 LEU A CD1 1 
ATOM   2558 C  CD2 . LEU A 1 381 ? 94.206  98.433  115.466 1.00 74.66 ? 369 LEU A CD2 1 
ATOM   2559 N  N   . ALA A 1 382 ? 96.258  102.304 117.268 1.00 85.85 ? 370 ALA A N   1 
ATOM   2560 C  CA  . ALA A 1 382 ? 97.310  102.230 118.274 1.00 85.85 ? 370 ALA A CA  1 
ATOM   2561 C  C   . ALA A 1 382 ? 97.100  103.292 119.319 1.00 85.85 ? 370 ALA A C   1 
ATOM   2562 O  O   . ALA A 1 382 ? 97.388  103.075 120.483 1.00 85.85 ? 370 ALA A O   1 
ATOM   2563 C  CB  . ALA A 1 382 ? 98.676  102.375 117.634 1.00 85.85 ? 370 ALA A CB  1 
ATOM   2564 N  N   . PHE A 1 383 ? 96.634  104.457 118.902 1.00 91.78 ? 371 PHE A N   1 
ATOM   2565 C  CA  . PHE A 1 383 ? 96.369  105.550 119.826 1.00 91.78 ? 371 PHE A CA  1 
ATOM   2566 C  C   . PHE A 1 383 ? 95.160  105.293 120.700 1.00 91.78 ? 371 PHE A C   1 
ATOM   2567 O  O   . PHE A 1 383 ? 94.918  106.029 121.643 1.00 91.78 ? 371 PHE A O   1 
ATOM   2568 C  CB  . PHE A 1 383 ? 96.269  106.864 119.072 1.00 91.78 ? 371 PHE A CB  1 
ATOM   2569 C  CG  . PHE A 1 383 ? 97.567  107.296 118.461 1.00 91.78 ? 371 PHE A CG  1 
ATOM   2570 C  CD1 . PHE A 1 383 ? 98.546  107.885 119.239 1.00 91.78 ? 371 PHE A CD1 1 
ATOM   2571 C  CD2 . PHE A 1 383 ? 97.820  107.091 117.118 1.00 91.78 ? 371 PHE A CD2 1 
ATOM   2572 C  CE1 . PHE A 1 383 ? 99.748  108.275 118.687 1.00 91.78 ? 371 PHE A CE1 1 
ATOM   2573 C  CE2 . PHE A 1 383 ? 99.019  107.478 116.559 1.00 91.78 ? 371 PHE A CE2 1 
ATOM   2574 C  CZ  . PHE A 1 383 ? 99.985  108.072 117.345 1.00 91.78 ? 371 PHE A CZ  1 
ATOM   2575 N  N   . ILE A 1 384 ? 94.348  104.306 120.355 1.00 89.21 ? 372 ILE A N   1 
ATOM   2576 C  CA  . ILE A 1 384 ? 93.246  103.942 121.227 1.00 89.21 ? 372 ILE A CA  1 
ATOM   2577 C  C   . ILE A 1 384 ? 93.599  102.721 122.083 1.00 89.21 ? 372 ILE A C   1 
ATOM   2578 O  O   . ILE A 1 384 ? 93.492  102.766 123.310 1.00 89.21 ? 372 ILE A O   1 
ATOM   2579 C  CB  . ILE A 1 384 ? 91.978  103.655 120.404 1.00 89.21 ? 372 ILE A CB  1 
ATOM   2580 C  CG1 . ILE A 1 384 ? 91.581  104.890 119.597 1.00 89.21 ? 372 ILE A CG1 1 
ATOM   2581 C  CG2 . ILE A 1 384 ? 90.831  103.232 121.306 1.00 89.21 ? 372 ILE A CG2 1 
ATOM   2582 C  CD1 . ILE A 1 384 ? 90.452  104.645 118.624 1.00 89.21 ? 372 ILE A CD1 1 
ATOM   2583 N  N   . ALA A 1 385 ? 94.068  101.645 121.455 1.00 84.57 ? 373 ALA A N   1 
ATOM   2584 C  CA  . ALA A 1 385 ? 94.356  100.418 122.199 1.00 84.57 ? 373 ALA A CA  1 
ATOM   2585 C  C   . ALA A 1 385 ? 95.497  100.470 123.207 1.00 84.57 ? 373 ALA A C   1 
ATOM   2586 O  O   . ALA A 1 385 ? 95.338  100.064 124.354 1.00 84.57 ? 373 ALA A O   1 
ATOM   2587 C  CB  . ALA A 1 385 ? 94.588  99.277  121.226 1.00 84.57 ? 373 ALA A CB  1 
ATOM   2588 N  N   . TYR A 1 386 ? 96.663  100.927 122.783 1.00 85.36 ? 374 TYR A N   1 
ATOM   2589 C  CA  . TYR A 1 386 ? 97.803  100.999 123.693 1.00 85.36 ? 374 TYR A CA  1 
ATOM   2590 C  C   . TYR A 1 386 ? 97.611  101.973 124.860 1.00 85.36 ? 374 TYR A C   1 
ATOM   2591 O  O   . TYR A 1 386 ? 97.982  101.651 125.978 1.00 85.36 ? 374 TYR A O   1 
ATOM   2592 C  CB  . TYR A 1 386 ? 99.115  101.216 122.940 1.00 85.36 ? 374 TYR A CB  1 
ATOM   2593 C  CG  . TYR A 1 386 ? 99.586  100.003 122.177 1.00 85.36 ? 374 TYR A CG  1 
ATOM   2594 C  CD1 . TYR A 1 386 ? 99.641  98.757  122.783 1.00 85.36 ? 374 TYR A CD1 1 
ATOM   2595 C  CD2 . TYR A 1 386 ? 99.993  100.104 120.857 1.00 85.36 ? 374 TYR A CD2 1 
ATOM   2596 C  CE1 . TYR A 1 386 ? 100.077 97.645  122.094 1.00 85.36 ? 374 TYR A CE1 1 
ATOM   2597 C  CE2 . TYR A 1 386 ? 100.435 98.999  120.161 1.00 85.36 ? 374 TYR A CE2 1 
ATOM   2598 C  CZ  . TYR A 1 386 ? 100.474 97.772  120.784 1.00 85.36 ? 374 TYR A CZ  1 
ATOM   2599 O  OH  . TYR A 1 386 ? 100.911 96.669  120.089 1.00 85.36 ? 374 TYR A OH  1 
ATOM   2600 N  N   . PRO A 1 387 ? 97.033  103.162 124.619 1.00 91.24 ? 375 PRO A N   1 
ATOM   2601 C  CA  . PRO A 1 387 ? 96.732  104.031 125.755 1.00 91.24 ? 375 PRO A CA  1 
ATOM   2602 C  C   . PRO A 1 387 ? 95.749  103.410 126.742 1.00 91.24 ? 375 PRO A C   1 
ATOM   2603 O  O   . PRO A 1 387 ? 95.916  103.624 127.936 1.00 91.24 ? 375 PRO A O   1 
ATOM   2604 C  CB  . PRO A 1 387 ? 96.141  105.254 125.076 1.00 91.24 ? 375 PRO A CB  1 
ATOM   2605 C  CG  . PRO A 1 387 ? 96.991  105.379 123.878 1.00 91.24 ? 375 PRO A CG  1 
ATOM   2606 C  CD  . PRO A 1 387 ? 97.110  103.964 123.386 1.00 91.24 ? 375 PRO A CD  1 
ATOM   2607 N  N   . LYS A 1 388 ? 94.738  102.687 126.281 1.00 89.23 ? 376 LYS A N   1 
ATOM   2608 C  CA  . LYS A 1 388 ? 93.830  101.993 127.192 1.00 89.23 ? 376 LYS A CA  1 
ATOM   2609 C  C   . LYS A 1 388 ? 94.568  100.988 128.077 1.00 89.23 ? 376 LYS A C   1 
ATOM   2610 O  O   . LYS A 1 388 ? 94.288  100.897 129.267 1.00 89.23 ? 376 LYS A O   1 
ATOM   2611 C  CB  . LYS A 1 388 ? 92.733  101.286 126.400 1.00 89.23 ? 376 LYS A CB  1 
ATOM   2612 C  CG  . LYS A 1 388 ? 91.745  100.491 127.235 1.00 89.23 ? 376 LYS A CG  1 
ATOM   2613 C  CD  . LYS A 1 388 ? 90.887  101.395 128.100 1.00 89.23 ? 376 LYS A CD  1 
ATOM   2614 C  CE  . LYS A 1 388 ? 89.939  100.581 128.962 1.00 89.23 ? 376 LYS A CE  1 
ATOM   2615 N  NZ  . LYS A 1 388 ? 89.040  99.739  128.129 1.00 89.23 ? 376 LYS A NZ  1 
ATOM   2616 N  N   . ALA A 1 389 ? 95.503  100.232 127.509 1.00 86.25 ? 377 ALA A N   1 
ATOM   2617 C  CA  . ALA A 1 389 ? 96.276  99.245  128.264 1.00 86.25 ? 377 ALA A CA  1 
ATOM   2618 C  C   . ALA A 1 389 ? 97.073  99.912  129.348 1.00 86.25 ? 377 ALA A C   1 
ATOM   2619 O  O   . ALA A 1 389 ? 97.200  99.381  130.442 1.00 86.25 ? 377 ALA A O   1 
ATOM   2620 C  CB  . ALA A 1 389 ? 97.219  98.513  127.336 1.00 86.25 ? 377 ALA A CB  1 
ATOM   2621 N  N   . VAL A 1 390 ? 97.626  101.075 129.042 1.00 89.57 ? 378 VAL A N   1 
ATOM   2622 C  CA  . VAL A 1 390 ? 98.433  101.810 129.998 1.00 89.57 ? 378 VAL A CA  1 
ATOM   2623 C  C   . VAL A 1 390 ? 97.598  102.182 131.213 1.00 89.57 ? 378 VAL A C   1 
ATOM   2624 O  O   . VAL A 1 390 ? 98.073  102.098 132.339 1.00 89.57 ? 378 VAL A O   1 
ATOM   2625 C  CB  . VAL A 1 390 ? 99.033  103.043 129.307 1.00 89.57 ? 378 VAL A CB  1 
ATOM   2626 C  CG1 . VAL A 1 390 ? 99.313  104.152 130.293 1.00 89.57 ? 378 VAL A CG1 1 
ATOM   2627 C  CG2 . VAL A 1 390 ? 100.271 102.665 128.513 1.00 89.57 ? 378 VAL A CG2 1 
ATOM   2628 N  N   . THR A 1 391 ? 96.345  102.558 130.994 1.00 90.59 ? 379 THR A N   1 
ATOM   2629 C  CA  . THR A 1 391 ? 95.453  102.900 132.096 1.00 90.59 ? 379 THR A CA  1 
ATOM   2630 C  C   . THR A 1 391 ? 95.305  101.698 133.014 1.00 90.59 ? 379 THR A C   1 
ATOM   2631 O  O   . THR A 1 391 ? 95.371  101.834 134.234 1.00 90.59 ? 379 THR A O   1 
ATOM   2632 C  CB  . THR A 1 391 ? 94.082  103.341 131.564 1.00 90.59 ? 379 THR A CB  1 
ATOM   2633 O  OG1 . THR A 1 391 ? 94.251  104.447 130.669 1.00 90.59 ? 379 THR A OG1 1 
ATOM   2634 C  CG2 . THR A 1 391 ? 93.171  103.753 132.701 1.00 90.59 ? 379 THR A CG2 1 
ATOM   2635 N  N   . MET A 1 392 ? 95.114  100.517 132.439 1.00 85.65 ? 380 MET A N   1 
ATOM   2636 C  CA  . MET A 1 392 ? 95.020  99.290  133.223 1.00 85.65 ? 380 MET A CA  1 
ATOM   2637 C  C   . MET A 1 392 ? 96.325  99.008  133.948 1.00 85.65 ? 380 MET A C   1 
ATOM   2638 O  O   . MET A 1 392 ? 96.319  98.524  135.076 1.00 85.65 ? 380 MET A O   1 
ATOM   2639 C  CB  . MET A 1 392 ? 94.643  98.125  132.317 1.00 85.65 ? 380 MET A CB  1 
ATOM   2640 C  CG  . MET A 1 392 ? 93.255  98.249  131.721 1.00 85.65 ? 380 MET A CG  1 
ATOM   2641 S  SD  . MET A 1 392 ? 91.998  98.126  133.004 1.00 85.65 ? 380 MET A SD  1 
ATOM   2642 C  CE  . MET A 1 392 ? 90.821  99.356  132.453 1.00 85.65 ? 380 MET A CE  1 
ATOM   2643 N  N   . MET A 1 393 ? 97.446  99.287  133.297 1.00 85.18 ? 381 MET A N   1 
ATOM   2644 C  CA  . MET A 1 393 ? 98.749  99.077  133.914 1.00 85.18 ? 381 MET A CA  1 
ATOM   2645 C  C   . MET A 1 393 ? 98.958  99.867  135.240 1.00 85.18 ? 381 MET A C   1 
ATOM   2646 O  O   . MET A 1 393 ? 98.562  101.026 135.314 1.00 85.18 ? 381 MET A O   1 
ATOM   2647 C  CB  . MET A 1 393 ? 99.876  99.366  132.924 1.00 85.18 ? 381 MET A CB  1 
ATOM   2648 C  CG  . MET A 1 393 ? 100.742 98.162  132.613 1.00 85.18 ? 381 MET A CG  1 
ATOM   2649 S  SD  . MET A 1 393 ? 101.918 98.487  131.293 1.00 85.18 ? 381 MET A SD  1 
ATOM   2650 C  CE  . MET A 1 393 ? 100.823 98.723  129.900 1.00 85.18 ? 381 MET A CE  1 
ATOM   2651 N  N   . PRO A 1 394 ? 99.576  99.248  136.293 1.00 86.97 ? 382 PRO A N   1 
ATOM   2652 C  CA  . PRO A 1 394 ? 99.816  99.980  137.546 1.00 86.97 ? 382 PRO A CA  1 
ATOM   2653 C  C   . PRO A 1 394 ? 100.713 101.178 137.310 1.00 86.97 ? 382 PRO A C   1 
ATOM   2654 O  O   . PRO A 1 394 ? 101.582 101.056 136.458 1.00 86.97 ? 382 PRO A O   1 
ATOM   2655 C  CB  . PRO A 1 394 ? 100.561 98.958  138.402 1.00 86.97 ? 382 PRO A CB  1 
ATOM   2656 C  CG  . PRO A 1 394 ? 100.127 97.636  137.876 1.00 86.97 ? 382 PRO A CG  1 
ATOM   2657 C  CD  . PRO A 1 394 ? 99.976  97.834  136.398 1.00 86.97 ? 382 PRO A CD  1 
ATOM   2658 N  N   . LEU A 1 395 ? 100.543 102.282 138.041 1.00 91.16 ? 383 LEU A N   1 
ATOM   2659 C  CA  . LEU A 1 395 ? 101.316 103.505 137.769 1.00 91.16 ? 383 LEU A CA  1 
ATOM   2660 C  C   . LEU A 1 395 ? 101.154 103.914 136.319 1.00 91.16 ? 383 LEU A C   1 
ATOM   2661 O  O   . LEU A 1 395 ? 102.136 103.970 135.587 1.00 91.16 ? 383 LEU A O   1 
ATOM   2662 C  CB  . LEU A 1 395 ? 102.792 103.322 138.126 1.00 91.16 ? 383 LEU A CB  1 
ATOM   2663 C  CG  . LEU A 1 395 ? 103.529 104.530 138.705 1.00 91.16 ? 383 LEU A CG  1 
ATOM   2664 C  CD1 . LEU A 1 395 ? 102.831 105.015 139.966 1.00 91.16 ? 383 LEU A CD1 1 
ATOM   2665 C  CD2 . LEU A 1 395 ? 104.976 104.168 138.999 1.00 91.16 ? 383 LEU A CD2 1 
ATOM   2666 N  N   . PRO A 1 396 ? 99.920  104.220 135.888 1.00 92.57 ? 384 PRO A N   1 
ATOM   2667 C  CA  . PRO A 1 396 ? 99.675  104.478 134.462 1.00 92.57 ? 384 PRO A CA  1 
ATOM   2668 C  C   . PRO A 1 396 ? 100.453 105.613 133.822 1.00 92.57 ? 384 PRO A C   1 
ATOM   2669 O  O   . PRO A 1 396 ? 100.886 105.454 132.692 1.00 92.57 ? 384 PRO A O   1 
ATOM   2670 C  CB  . PRO A 1 396 ? 98.186  104.829 134.432 1.00 92.57 ? 384 PRO A CB  1 
ATOM   2671 C  CG  . PRO A 1 396 ? 97.621  104.335 135.719 1.00 92.57 ? 384 PRO A CG  1 
ATOM   2672 C  CD  . PRO A 1 396 ? 98.730  104.509 136.702 1.00 92.57 ? 384 PRO A CD  1 
ATOM   2673 N  N   . THR A 1 397 ? 100.600 106.740 134.501 1.00 95.60 ? 385 THR A N   1 
ATOM   2674 C  CA  . THR A 1 397 ? 101.313 107.882 133.948 1.00 95.60 ? 385 THR A CA  1 
ATOM   2675 C  C   . THR A 1 397 ? 102.704 107.468 133.505 1.00 95.60 ? 385 THR A C   1 
ATOM   2676 O  O   . THR A 1 397 ? 103.135 107.813 132.409 1.00 95.60 ? 385 THR A O   1 
ATOM   2677 C  CB  . THR A 1 397 ? 101.382 109.040 134.961 1.00 95.60 ? 385 THR A CB  1 
ATOM   2678 O  OG1 . THR A 1 397 ? 100.060 109.527 135.218 1.00 95.60 ? 385 THR A OG1 1 
ATOM   2679 C  CG2 . THR A 1 397 ? 102.233 110.181 134.434 1.00 95.60 ? 385 THR A CG2 1 
ATOM   2680 N  N   . PHE A 1 398 ? 103.394 106.691 134.329 1.00 93.47 ? 386 PHE A N   1 
ATOM   2681 C  CA  . PHE A 1 398 ? 104.754 106.282 134.006 1.00 93.47 ? 386 PHE A CA  1 
ATOM   2682 C  C   . PHE A 1 398 ? 104.799 105.460 132.731 1.00 93.47 ? 386 PHE A C   1 
ATOM   2683 O  O   . PHE A 1 398 ? 105.637 105.698 131.865 1.00 93.47 ? 386 PHE A O   1 
ATOM   2684 C  CB  . PHE A 1 398 ? 105.314 105.480 135.183 1.00 93.47 ? 386 PHE A CB  1 
ATOM   2685 C  CG  . PHE A 1 398 ? 106.630 104.818 134.912 1.00 93.47 ? 386 PHE A CG  1 
ATOM   2686 C  CD1 . PHE A 1 398 ? 107.777 105.570 134.738 1.00 93.47 ? 386 PHE A CD1 1 
ATOM   2687 C  CD2 . PHE A 1 398 ? 106.725 103.439 134.869 1.00 93.47 ? 386 PHE A CD2 1 
ATOM   2688 C  CE1 . PHE A 1 398 ? 108.991 104.959 134.499 1.00 93.47 ? 386 PHE A CE1 1 
ATOM   2689 C  CE2 . PHE A 1 398 ? 107.935 102.821 134.631 1.00 93.47 ? 386 PHE A CE2 1 
ATOM   2690 C  CZ  . PHE A 1 398 ? 109.071 103.583 134.448 1.00 93.47 ? 386 PHE A CZ  1 
ATOM   2691 N  N   . TRP A 1 399 ? 103.883 104.516 132.593 1.00 91.31 ? 387 TRP A N   1 
ATOM   2692 C  CA  . TRP A 1 399 ? 103.825 103.700 131.390 1.00 91.31 ? 387 TRP A CA  1 
ATOM   2693 C  C   . TRP A 1 399 ? 103.466 104.478 130.143 1.00 91.31 ? 387 TRP A C   1 
ATOM   2694 O  O   . TRP A 1 399 ? 103.992 104.206 129.074 1.00 91.31 ? 387 TRP A O   1 
ATOM   2695 C  CB  . TRP A 1 399 ? 102.917 102.501 131.598 1.00 91.31 ? 387 TRP A CB  1 
ATOM   2696 C  CG  . TRP A 1 399 ? 103.453 101.599 132.641 1.00 91.31 ? 387 TRP A CG  1 
ATOM   2697 C  CD1 . TRP A 1 399 ? 102.914 101.357 133.858 1.00 91.31 ? 387 TRP A CD1 1 
ATOM   2698 C  CD2 . TRP A 1 399 ? 104.666 100.840 132.579 1.00 91.31 ? 387 TRP A CD2 1 
ATOM   2699 N  NE1 . TRP A 1 399 ? 103.700 100.480 134.562 1.00 91.31 ? 387 TRP A NE1 1 
ATOM   2700 C  CE2 . TRP A 1 399 ? 104.784 100.148 133.796 1.00 91.31 ? 387 TRP A CE2 1 
ATOM   2701 C  CE3 . TRP A 1 399 ? 105.657 100.671 131.608 1.00 91.31 ? 387 TRP A CE3 1 
ATOM   2702 C  CZ2 . TRP A 1 399 ? 105.852 99.301  134.071 1.00 91.31 ? 387 TRP A CZ2 1 
ATOM   2703 C  CZ3 . TRP A 1 399 ? 106.715 99.834  131.883 1.00 91.31 ? 387 TRP A CZ3 1 
ATOM   2704 C  CH2 . TRP A 1 399 ? 106.805 99.158  133.103 1.00 91.31 ? 387 TRP A CH2 1 
ATOM   2705 N  N   . SER A 1 400 ? 102.561 105.436 130.271 1.00 94.77 ? 388 SER A N   1 
ATOM   2706 C  CA  . SER A 1 400 ? 102.178 106.256 129.137 1.00 94.77 ? 388 SER A CA  1 
ATOM   2707 C  C   . SER A 1 400 ? 103.352 107.046 128.615 1.00 94.77 ? 388 SER A C   1 
ATOM   2708 O  O   . SER A 1 400 ? 103.565 107.124 127.415 1.00 94.77 ? 388 SER A O   1 
ATOM   2709 C  CB  . SER A 1 400 ? 101.085 107.228 129.545 1.00 94.77 ? 388 SER A CB  1 
ATOM   2710 O  OG  . SER A 1 400 ? 100.761 108.082 128.470 1.00 94.77 ? 388 SER A OG  1 
ATOM   2711 N  N   . ILE A 1 401 ? 104.141 107.610 129.514 1.00 95.54 ? 389 ILE A N   1 
ATOM   2712 C  CA  . ILE A 1 401 ? 105.265 108.407 129.089 1.00 95.54 ? 389 ILE A CA  1 
ATOM   2713 C  C   . ILE A 1 401 ? 106.206 107.507 128.317 1.00 95.54 ? 389 ILE A C   1 
ATOM   2714 O  O   . ILE A 1 401 ? 106.664 107.865 127.237 1.00 95.54 ? 389 ILE A O   1 
ATOM   2715 C  CB  . ILE A 1 401 ? 105.990 109.018 130.303 1.00 95.54 ? 389 ILE A CB  1 
ATOM   2716 C  CG1 . ILE A 1 401 ? 105.086 110.027 131.008 1.00 95.54 ? 389 ILE A CG1 1 
ATOM   2717 C  CG2 . ILE A 1 401 ? 107.285 109.695 129.890 1.00 95.54 ? 389 ILE A CG2 1 
ATOM   2718 C  CD1 . ILE A 1 401 ? 105.673 110.587 132.282 1.00 95.54 ? 389 ILE A CD1 1 
ATOM   2719 N  N   . LEU A 1 402 ? 106.445 106.310 128.832 1.00 92.85 ? 390 LEU A N   1 
ATOM   2720 C  CA  . LEU A 1 402 ? 107.365 105.394 128.187 1.00 92.85 ? 390 LEU A CA  1 
ATOM   2721 C  C   . LEU A 1 402 ? 106.896 104.959 126.820 1.00 92.85 ? 390 LEU A C   1 
ATOM   2722 O  O   . LEU A 1 402 ? 107.688 104.875 125.889 1.00 92.85 ? 390 LEU A O   1 
ATOM   2723 C  CB  . LEU A 1 402 ? 107.604 104.176 129.066 1.00 92.85 ? 390 LEU A CB  1 
ATOM   2724 C  CG  . LEU A 1 402 ? 108.391 104.365 130.357 1.00 92.85 ? 390 LEU A CG  1 
ATOM   2725 C  CD1 . LEU A 1 402 ? 108.777 102.995 130.884 1.00 92.85 ? 390 LEU A CD1 1 
ATOM   2726 C  CD2 . LEU A 1 402 ? 109.635 105.198 130.099 1.00 92.85 ? 390 LEU A CD2 1 
ATOM   2727 N  N   . PHE A 1 403 ? 105.610 104.675 126.689 1.00 92.02 ? 391 PHE A N   1 
ATOM   2728 C  CA  . PHE A 1 403 ? 105.100 104.227 125.414 1.00 92.02 ? 391 PHE A CA  1 
ATOM   2729 C  C   . PHE A 1 403 ? 105.252 105.295 124.353 1.00 92.02 ? 391 PHE A C   1 
ATOM   2730 O  O   . PHE A 1 403 ? 105.698 105.022 123.243 1.00 92.02 ? 391 PHE A O   1 
ATOM   2731 C  CB  . PHE A 1 403 ? 103.631 103.832 125.523 1.00 92.02 ? 391 PHE A CB  1 
ATOM   2732 C  CG  . PHE A 1 403 ? 103.008 103.522 124.200 1.00 92.02 ? 391 PHE A CG  1 
ATOM   2733 C  CD1 . PHE A 1 403 ? 103.427 102.426 123.469 1.00 92.02 ? 391 PHE A CD1 1 
ATOM   2734 C  CD2 . PHE A 1 403 ? 102.028 104.340 123.672 1.00 92.02 ? 391 PHE A CD2 1 
ATOM   2735 C  CE1 . PHE A 1 403 ? 102.875 102.148 122.240 1.00 92.02 ? 391 PHE A CE1 1 
ATOM   2736 C  CE2 . PHE A 1 403 ? 101.470 104.067 122.444 1.00 92.02 ? 391 PHE A CE2 1 
ATOM   2737 C  CZ  . PHE A 1 403 ? 101.897 102.974 121.726 1.00 92.02 ? 391 PHE A CZ  1 
ATOM   2738 N  N   . PHE A 1 404 ? 104.896 106.526 124.688 1.00 95.33 ? 392 PHE A N   1 
ATOM   2739 C  CA  . PHE A 1 404 ? 104.960 107.591 123.703 1.00 95.33 ? 392 PHE A CA  1 
ATOM   2740 C  C   . PHE A 1 404 ? 106.389 107.991 123.438 1.00 95.33 ? 392 PHE A C   1 
ATOM   2741 O  O   . PHE A 1 404 ? 106.708 108.398 122.332 1.00 95.33 ? 392 PHE A O   1 
ATOM   2742 C  CB  . PHE A 1 404 ? 104.007 108.721 124.059 1.00 95.33 ? 392 PHE A CB  1 
ATOM   2743 C  CG  . PHE A 1 404 ? 102.574 108.303 123.973 1.00 95.33 ? 392 PHE A CG  1 
ATOM   2744 C  CD1 . PHE A 1 404 ? 102.014 107.997 122.746 1.00 95.33 ? 392 PHE A CD1 1 
ATOM   2745 C  CD2 . PHE A 1 404 ? 101.806 108.157 125.110 1.00 95.33 ? 392 PHE A CD2 1 
ATOM   2746 C  CE1 . PHE A 1 404 ? 100.704 107.581 122.653 1.00 95.33 ? 392 PHE A CE1 1 
ATOM   2747 C  CE2 . PHE A 1 404 ? 100.496 107.739 125.027 1.00 95.33 ? 392 PHE A CE2 1 
ATOM   2748 C  CZ  . PHE A 1 404 ? 99.946  107.448 123.797 1.00 95.33 ? 392 PHE A CZ  1 
ATOM   2749 N  N   . ILE A 1 405 ? 107.274 107.811 124.409 1.00 95.36 ? 393 ILE A N   1 
ATOM   2750 C  CA  . ILE A 1 405 ? 108.692 108.055 124.165 1.00 95.36 ? 393 ILE A CA  1 
ATOM   2751 C  C   . ILE A 1 405 ? 109.186 106.980 123.205 1.00 95.36 ? 393 ILE A C   1 
ATOM   2752 O  O   . ILE A 1 405 ? 109.908 107.278 122.266 1.00 95.36 ? 393 ILE A O   1 
ATOM   2753 C  CB  . ILE A 1 405 ? 109.522 108.051 125.464 1.00 95.36 ? 393 ILE A CB  1 
ATOM   2754 C  CG1 . ILE A 1 405 ? 109.373 109.382 126.193 1.00 95.36 ? 393 ILE A CG1 1 
ATOM   2755 C  CG2 . ILE A 1 405 ? 110.996 107.818 125.183 1.00 95.36 ? 393 ILE A CG2 1 
ATOM   2756 C  CD1 . ILE A 1 405 ? 110.221 109.482 127.440 1.00 95.36 ? 393 ILE A CD1 1 
ATOM   2757 N  N   . MET A 1 406 ? 108.764 105.737 123.404 1.00 93.99 ? 394 MET A N   1 
ATOM   2758 C  CA  . MET A 1 406 ? 109.163 104.650 122.510 1.00 93.99 ? 394 MET A CA  1 
ATOM   2759 C  C   . MET A 1 406 ? 108.654 104.890 121.111 1.00 93.99 ? 394 MET A C   1 
ATOM   2760 O  O   . MET A 1 406 ? 109.371 104.676 120.142 1.00 93.99 ? 394 MET A O   1 
ATOM   2761 C  CB  . MET A 1 406 ? 108.607 103.317 123.006 1.00 93.99 ? 394 MET A CB  1 
ATOM   2762 C  CG  . MET A 1 406 ? 108.870 102.146 122.084 1.00 93.99 ? 394 MET A CG  1 
ATOM   2763 S  SD  . MET A 1 406 ? 107.567 100.905 122.127 1.00 93.99 ? 394 MET A SD  1 
ATOM   2764 C  CE  . MET A 1 406 ? 106.364 101.633 121.028 1.00 93.99 ? 394 MET A CE  1 
ATOM   2765 N  N   . LEU A 1 407 ? 107.403 105.309 120.997 1.00 93.90 ? 395 LEU A N   1 
ATOM   2766 C  CA  . LEU A 1 407 ? 106.816 105.573 119.698 1.00 93.90 ? 395 LEU A CA  1 
ATOM   2767 C  C   . LEU A 1 407 ? 107.650 106.631 119.033 1.00 93.90 ? 395 LEU A C   1 
ATOM   2768 O  O   . LEU A 1 407 ? 107.958 106.533 117.854 1.00 93.90 ? 395 LEU A O   1 
ATOM   2769 C  CB  . LEU A 1 407 ? 105.382 106.050 119.883 1.00 93.90 ? 395 LEU A CB  1 
ATOM   2770 C  CG  . LEU A 1 407 ? 104.299 105.500 118.961 1.00 93.90 ? 395 LEU A CG  1 
ATOM   2771 C  CD1 . LEU A 1 407 ? 104.327 103.982 118.966 1.00 93.90 ? 395 LEU A CD1 1 
ATOM   2772 C  CD2 . LEU A 1 407 ? 102.937 106.012 119.395 1.00 93.90 ? 395 LEU A CD2 1 
ATOM   2773 N  N   . LEU A 1 408 ? 108.026 107.650 119.793 1.00 96.25 ? 396 LEU A N   1 
ATOM   2774 C  CA  . LEU A 1 408 ? 108.858 108.722 119.264 1.00 96.25 ? 396 LEU A CA  1 
ATOM   2775 C  C   . LEU A 1 408 ? 110.246 108.262 118.847 1.00 96.25 ? 396 LEU A C   1 
ATOM   2776 O  O   . LEU A 1 408 ? 110.732 108.661 117.807 1.00 96.25 ? 396 LEU A O   1 
ATOM   2777 C  CB  . LEU A 1 408 ? 108.961 109.845 120.289 1.00 96.25 ? 396 LEU A CB  1 
ATOM   2778 C  CG  . LEU A 1 408 ? 107.684 110.603 120.639 1.00 96.25 ? 396 LEU A CG  1 
ATOM   2779 C  CD1 . LEU A 1 408 ? 106.597 109.628 121.045 1.00 96.25 ? 396 LEU A CD1 1 
ATOM   2780 C  CD2 . LEU A 1 408 ? 107.974 111.568 121.775 1.00 96.25 ? 396 LEU A CD2 1 
ATOM   2781 N  N   . LEU A 1 409 ? 110.880 107.412 119.643 1.00 96.46 ? 397 LEU A N   1 
ATOM   2782 C  CA  . LEU A 1 409 ? 112.227 106.945 119.333 1.00 96.46 ? 397 LEU A CA  1 
ATOM   2783 C  C   . LEU A 1 409 ? 112.257 106.102 118.077 1.00 96.46 ? 397 LEU A C   1 
ATOM   2784 O  O   . LEU A 1 409 ? 113.192 106.197 117.296 1.00 96.46 ? 397 LEU A O   1 
ATOM   2785 C  CB  . LEU A 1 409 ? 112.820 106.158 120.499 1.00 96.46 ? 397 LEU A CB  1 
ATOM   2786 C  CG  . LEU A 1 409 ? 113.162 106.943 121.764 1.00 96.46 ? 397 LEU A CG  1 
ATOM   2787 C  CD1 . LEU A 1 409 ? 113.871 106.043 122.762 1.00 96.46 ? 397 LEU A CD1 1 
ATOM   2788 C  CD2 . LEU A 1 409 ? 114.021 108.148 121.423 1.00 96.46 ? 397 LEU A CD2 1 
ATOM   2789 N  N   . LEU A 1 410 ? 111.242 105.275 117.878 1.00 95.24 ? 398 LEU A N   1 
ATOM   2790 C  CA  . LEU A 1 410 ? 111.166 104.466 116.677 1.00 95.24 ? 398 LEU A CA  1 
ATOM   2791 C  C   . LEU A 1 410 ? 110.905 105.307 115.451 1.00 95.24 ? 398 LEU A C   1 
ATOM   2792 O  O   . LEU A 1 410 ? 111.589 105.178 114.441 1.00 95.24 ? 398 LEU A O   1 
ATOM   2793 C  CB  . LEU A 1 410 ? 110.049 103.440 116.814 1.00 95.24 ? 398 LEU A CB  1 
ATOM   2794 C  CG  . LEU A 1 410 ? 110.361 102.236 117.689 1.00 95.24 ? 398 LEU A CG  1 
ATOM   2795 C  CD1 . LEU A 1 410 ? 109.181 101.282 117.681 1.00 95.24 ? 398 LEU A CD1 1 
ATOM   2796 C  CD2 . LEU A 1 410 ? 111.607 101.558 117.149 1.00 95.24 ? 398 LEU A CD2 1 
ATOM   2797 N  N   . GLY A 1 411 ? 109.945 106.208 115.546 1.00 95.96 ? 399 GLY A N   1 
ATOM   2798 C  CA  . GLY A 1 411 ? 109.647 107.068 114.431 1.00 95.96 ? 399 GLY A CA  1 
ATOM   2799 C  C   . GLY A 1 411 ? 110.709 108.061 114.061 1.00 95.96 ? 399 GLY A C   1 
ATOM   2800 O  O   . GLY A 1 411 ? 110.977 108.261 112.888 1.00 95.96 ? 399 GLY A O   1 
ATOM   2801 N  N   . LEU A 1 412 ? 111.311 108.701 115.052 1.00 96.78 ? 400 LEU A N   1 
ATOM   2802 C  CA  . LEU A 1 412 ? 112.298 109.723 114.773 1.00 96.78 ? 400 LEU A CA  1 
ATOM   2803 C  C   . LEU A 1 412 ? 113.496 109.136 114.087 1.00 96.78 ? 400 LEU A C   1 
ATOM   2804 O  O   . LEU A 1 412 ? 114.018 109.711 113.148 1.00 96.78 ? 400 LEU A O   1 
ATOM   2805 C  CB  . LEU A 1 412 ? 112.713 110.456 116.040 1.00 96.78 ? 400 LEU A CB  1 
ATOM   2806 C  CG  . LEU A 1 412 ? 111.771 111.570 116.493 1.00 96.78 ? 400 LEU A CG  1 
ATOM   2807 C  CD1 . LEU A 1 412 ? 112.180 112.099 117.858 1.00 96.78 ? 400 LEU A CD1 1 
ATOM   2808 C  CD2 . LEU A 1 412 ? 111.756 112.684 115.462 1.00 96.78 ? 400 LEU A CD2 1 
ATOM   2809 N  N   . ASP A 1 413 ? 113.949 107.989 114.564 1.00 96.09 ? 401 ASP A N   1 
ATOM   2810 C  CA  . ASP A 1 413 ? 115.076 107.330 113.936 1.00 96.09 ? 401 ASP A CA  1 
ATOM   2811 C  C   . ASP A 1 413 ? 114.780 107.109 112.478 1.00 96.09 ? 401 ASP A C   1 
ATOM   2812 O  O   . ASP A 1 413 ? 115.580 107.460 111.619 1.00 96.09 ? 401 ASP A O   1 
ATOM   2813 C  CB  . ASP A 1 413 ? 115.366 106.002 114.611 1.00 96.09 ? 401 ASP A CB  1 
ATOM   2814 C  CG  . ASP A 1 413 ? 116.066 106.168 115.940 1.00 96.09 ? 401 ASP A CG  1 
ATOM   2815 O  OD1 . ASP A 1 413 ? 116.185 107.319 116.412 1.00 96.09 ? 401 ASP A OD1 1 
ATOM   2816 O  OD2 . ASP A 1 413 ? 116.499 105.148 116.512 1.00 96.09 ? 401 ASP A OD2 1 
ATOM   2817 N  N   . SER A 1 414 ? 113.620 106.541 112.190 1.00 95.69 ? 402 SER A N   1 
ATOM   2818 C  CA  . SER A 1 414 ? 113.248 106.271 110.818 1.00 95.69 ? 402 SER A CA  1 
ATOM   2819 C  C   . SER A 1 414 ? 113.127 107.537 110.002 1.00 95.69 ? 402 SER A C   1 
ATOM   2820 O  O   . SER A 1 414 ? 113.590 107.590 108.871 1.00 95.69 ? 402 SER A O   1 
ATOM   2821 C  CB  . SER A 1 414 ? 111.918 105.535 110.795 1.00 95.69 ? 402 SER A CB  1 
ATOM   2822 O  OG  . SER A 1 414 ? 111.967 104.366 111.590 1.00 95.69 ? 402 SER A OG  1 
ATOM   2823 N  N   . GLN A 1 415 ? 112.514 108.564 110.572 1.00 96.88 ? 403 GLN A N   1 
ATOM   2824 C  CA  . GLN A 1 415 ? 112.347 109.823 109.871 1.00 96.88 ? 403 GLN A CA  1 
ATOM   2825 C  C   . GLN A 1 415 ? 113.681 110.488 109.562 1.00 96.88 ? 403 GLN A C   1 
ATOM   2826 O  O   . GLN A 1 415 ? 113.870 111.001 108.475 1.00 96.88 ? 403 GLN A O   1 
ATOM   2827 C  CB  . GLN A 1 415 ? 111.440 110.761 110.660 1.00 96.88 ? 403 GLN A CB  1 
ATOM   2828 C  CG  . GLN A 1 415 ? 111.123 112.076 109.967 1.00 96.88 ? 403 GLN A CG  1 
ATOM   2829 C  CD  . GLN A 1 415 ? 110.036 111.972 108.917 1.00 96.88 ? 403 GLN A CD  1 
ATOM   2830 O  OE1 . GLN A 1 415 ? 109.360 110.956 108.799 1.00 96.88 ? 403 GLN A OE1 1 
ATOM   2831 N  NE2 . GLN A 1 415 ? 109.854 113.040 108.156 1.00 96.88 ? 403 GLN A NE2 1 
ATOM   2832 N  N   . PHE A 1 416 ? 114.624 110.454 110.497 1.00 95.64 ? 404 PHE A N   1 
ATOM   2833 C  CA  . PHE A 1 416 ? 115.909 111.061 110.236 1.00 95.64 ? 404 PHE A CA  1 
ATOM   2834 C  C   . PHE A 1 416 ? 116.550 110.348 109.074 1.00 95.64 ? 404 PHE A C   1 
ATOM   2835 O  O   . PHE A 1 416 ? 117.045 110.986 108.159 1.00 95.64 ? 404 PHE A O   1 
ATOM   2836 C  CB  . PHE A 1 416 ? 116.876 110.912 111.413 1.00 95.64 ? 404 PHE A CB  1 
ATOM   2837 C  CG  . PHE A 1 416 ? 116.418 111.544 112.688 1.00 95.64 ? 404 PHE A CG  1 
ATOM   2838 C  CD1 . PHE A 1 416 ? 115.585 112.643 112.688 1.00 95.64 ? 404 PHE A CD1 1 
ATOM   2839 C  CD2 . PHE A 1 416 ? 116.858 111.041 113.900 1.00 95.64 ? 404 PHE A CD2 1 
ATOM   2840 C  CE1 . PHE A 1 416 ? 115.176 113.211 113.877 1.00 95.64 ? 404 PHE A CE1 1 
ATOM   2841 C  CE2 . PHE A 1 416 ? 116.456 111.606 115.090 1.00 95.64 ? 404 PHE A CE2 1 
ATOM   2842 C  CZ  . PHE A 1 416 ? 115.614 112.695 115.077 1.00 95.64 ? 404 PHE A CZ  1 
ATOM   2843 N  N   . VAL A 1 417 ? 116.513 109.024 109.083 1.00 96.10 ? 405 VAL A N   1 
ATOM   2844 C  CA  . VAL A 1 417 ? 117.178 108.273 108.037 1.00 96.10 ? 405 VAL A CA  1 
ATOM   2845 C  C   . VAL A 1 417 ? 116.541 108.565 106.703 1.00 96.10 ? 405 VAL A C   1 
ATOM   2846 O  O   . VAL A 1 417 ? 117.229 108.816 105.717 1.00 96.10 ? 405 VAL A O   1 
ATOM   2847 C  CB  . VAL A 1 417 ? 117.104 106.756 108.312 1.00 96.10 ? 405 VAL A CB  1 
ATOM   2848 C  CG1 . VAL A 1 417 ? 117.595 105.954 107.116 1.00 96.10 ? 405 VAL A CG1 1 
ATOM   2849 C  CG2 . VAL A 1 417 ? 117.901 106.392 109.548 1.00 96.10 ? 405 VAL A CG2 1 
ATOM   2850 N  N   . GLU A 1 418 ? 115.220 108.564 106.672 1.00 96.84 ? 406 GLU A N   1 
ATOM   2851 C  CA  . GLU A 1 418 ? 114.525 108.785 105.425 1.00 96.84 ? 406 GLU A CA  1 
ATOM   2852 C  C   . GLU A 1 418 ? 114.721 110.181 104.858 1.00 96.84 ? 406 GLU A C   1 
ATOM   2853 O  O   . GLU A 1 418 ? 114.933 110.333 103.662 1.00 96.84 ? 406 GLU A O   1 
ATOM   2854 C  CB  . GLU A 1 418 ? 113.048 108.445 105.592 1.00 96.84 ? 406 GLU A CB  1 
ATOM   2855 C  CG  . GLU A 1 418 ? 112.491 107.585 104.472 1.00 96.84 ? 406 GLU A CG  1 
ATOM   2856 C  CD  . GLU A 1 418 ? 113.208 106.255 104.346 1.00 96.84 ? 406 GLU A CD  1 
ATOM   2857 O  OE1 . GLU A 1 418 ? 113.764 105.979 103.263 1.00 96.84 ? 406 GLU A OE1 1 
ATOM   2858 O  OE2 . GLU A 1 418 ? 113.223 105.488 105.331 1.00 96.84 ? 406 GLU A OE2 1 
ATOM   2859 N  N   . VAL A 1 419 ? 114.646 111.202 105.703 1.00 97.30 ? 407 VAL A N   1 
ATOM   2860 C  CA  . VAL A 1 419 ? 114.888 112.565 105.243 1.00 97.30 ? 407 VAL A CA  1 
ATOM   2861 C  C   . VAL A 1 419 ? 116.336 112.782 104.814 1.00 97.30 ? 407 VAL A C   1 
ATOM   2862 O  O   . VAL A 1 419 ? 116.587 113.431 103.808 1.00 97.30 ? 407 VAL A O   1 
ATOM   2863 C  CB  . VAL A 1 419 ? 114.370 113.629 106.227 1.00 97.30 ? 407 VAL A CB  1 
ATOM   2864 C  CG1 . VAL A 1 419 ? 114.444 115.012 105.605 1.00 97.30 ? 407 VAL A CG1 1 
ATOM   2865 C  CG2 . VAL A 1 419 ? 112.926 113.340 106.587 1.00 97.30 ? 407 VAL A CG2 1 
ATOM   2866 N  N   . GLU A 1 420 ? 117.294 112.215 105.539 1.00 96.10 ? 408 GLU A N   1 
ATOM   2867 C  CA  . GLU A 1 420 ? 118.684 112.320 105.120 1.00 96.10 ? 408 GLU A CA  1 
ATOM   2868 C  C   . GLU A 1 420 ? 118.850 111.655 103.778 1.00 96.10 ? 408 GLU A C   1 
ATOM   2869 O  O   . GLU A 1 420 ? 119.516 112.185 102.901 1.00 96.10 ? 408 GLU A O   1 
ATOM   2870 C  CB  . GLU A 1 420 ? 119.598 111.597 106.095 1.00 96.10 ? 408 GLU A CB  1 
ATOM   2871 C  CG  . GLU A 1 420 ? 119.954 112.360 107.350 1.00 96.10 ? 408 GLU A CG  1 
ATOM   2872 C  CD  . GLU A 1 420 ? 120.389 111.441 108.468 1.00 96.10 ? 408 GLU A CD  1 
ATOM   2873 O  OE1 . GLU A 1 420 ? 120.732 111.941 109.561 1.00 96.10 ? 408 GLU A OE1 1 
ATOM   2874 O  OE2 . GLU A 1 420 ? 120.378 110.212 108.249 1.00 96.10 ? 408 GLU A OE2 1 
ATOM   2875 N  N   . GLY A 1 421 ? 118.234 110.496 103.606 1.00 96.68 ? 409 GLY A N   1 
ATOM   2876 C  CA  . GLY A 1 421 ? 118.325 109.787 102.350 1.00 96.68 ? 409 GLY A CA  1 
ATOM   2877 C  C   . GLY A 1 421 ? 117.718 110.558 101.206 1.00 96.68 ? 409 GLY A C   1 
ATOM   2878 O  O   . GLY A 1 421 ? 118.291 110.608 100.124 1.00 96.68 ? 409 GLY A O   1 
ATOM   2879 N  N   . GLN A 1 422 ? 116.570 111.180 101.438 1.00 97.56 ? 410 GLN A N   1 
ATOM   2880 C  CA  . GLN A 1 422 ? 115.944 111.983 100.404 1.00 97.56 ? 410 GLN A CA  1 
ATOM   2881 C  C   . GLN A 1 422 ? 116.833 113.150 100.026 1.00 97.56 ? 410 GLN A C   1 
ATOM   2882 O  O   . GLN A 1 422 ? 117.051 113.411 98.850  1.00 97.56 ? 410 GLN A O   1 
ATOM   2883 C  CB  . GLN A 1 422 ? 114.610 112.523 100.906 1.00 97.56 ? 410 GLN A CB  1 
ATOM   2884 C  CG  . GLN A 1 422 ? 113.872 113.391 99.907  1.00 97.56 ? 410 GLN A CG  1 
ATOM   2885 C  CD  . GLN A 1 422 ? 112.828 114.259 100.569 1.00 97.56 ? 410 GLN A CD  1 
ATOM   2886 O  OE1 . GLN A 1 422 ? 112.636 114.196 101.780 1.00 97.56 ? 410 GLN A OE1 1 
ATOM   2887 N  NE2 . GLN A 1 422 ? 112.153 115.081 99.779  1.00 97.56 ? 410 GLN A NE2 1 
ATOM   2888 N  N   . ILE A 1 423 ? 117.344 113.858 101.024 1.00 97.23 ? 411 ILE A N   1 
ATOM   2889 C  CA  . ILE A 1 423 ? 118.185 115.014 100.759 1.00 97.23 ? 411 ILE A CA  1 
ATOM   2890 C  C   . ILE A 1 423 ? 119.467 114.609 100.046 1.00 97.23 ? 411 ILE A C   1 
ATOM   2891 O  O   . ILE A 1 423 ? 119.842 115.229 99.062  1.00 97.23 ? 411 ILE A O   1 
ATOM   2892 C  CB  . ILE A 1 423 ? 118.460 115.813 102.041 1.00 97.23 ? 411 ILE A CB  1 
ATOM   2893 C  CG1 . ILE A 1 423 ? 117.223 116.629 102.395 1.00 97.23 ? 411 ILE A CG1 1 
ATOM   2894 C  CG2 . ILE A 1 423 ? 119.653 116.739 101.872 1.00 97.23 ? 411 ILE A CG2 1 
ATOM   2895 C  CD1 . ILE A 1 423 ? 117.027 116.813 103.875 1.00 97.23 ? 411 ILE A CD1 1 
ATOM   2896 N  N   . THR A 1 424 ? 120.115 113.546 100.503 1.00 95.84 ? 412 THR A N   1 
ATOM   2897 C  CA  . THR A 1 424 ? 121.365 113.131 99.891  1.00 95.84 ? 412 THR A CA  1 
ATOM   2898 C  C   . THR A 1 424 ? 121.145 112.744 98.440  1.00 95.84 ? 412 THR A C   1 
ATOM   2899 O  O   . THR A 1 424 ? 121.901 113.149 97.567  1.00 95.84 ? 412 THR A O   1 
ATOM   2900 C  CB  . THR A 1 424 ? 121.989 111.940 100.636 1.00 95.84 ? 412 THR A CB  1 
ATOM   2901 O  OG1 . THR A 1 424 ? 122.216 112.299 102.003 1.00 95.84 ? 412 THR A OG1 1 
ATOM   2902 C  CG2 . THR A 1 424 ? 123.312 111.539 100.006 1.00 95.84 ? 412 THR A CG2 1 
ATOM   2903 N  N   . SER A 1 425 ? 120.085 111.995 98.170  1.00 96.60 ? 413 SER A N   1 
ATOM   2904 C  CA  . SER A 1 425 ? 119.803 111.580 96.806  1.00 96.60 ? 413 SER A CA  1 
ATOM   2905 C  C   . SER A 1 425 ? 119.500 112.777 95.926  1.00 96.60 ? 413 SER A C   1 
ATOM   2906 O  O   . SER A 1 425 ? 119.979 112.860 94.798  1.00 96.60 ? 413 SER A O   1 
ATOM   2907 C  CB  . SER A 1 425 ? 118.644 110.584 96.778  1.00 96.60 ? 413 SER A CB  1 
ATOM   2908 O  OG  . SER A 1 425 ? 117.445 111.174 97.238  1.00 96.60 ? 413 SER A OG  1 
ATOM   2909 N  N   . LEU A 1 426 ? 118.711 113.712 96.440  1.00 96.59 ? 414 LEU A N   1 
ATOM   2910 C  CA  . LEU A 1 426 ? 118.394 114.917 95.688  1.00 96.59 ? 414 LEU A CA  1 
ATOM   2911 C  C   . LEU A 1 426 ? 119.625 115.772 95.445  1.00 96.59 ? 414 LEU A C   1 
ATOM   2912 O  O   . LEU A 1 426 ? 119.791 116.324 94.361  1.00 96.59 ? 414 LEU A O   1 
ATOM   2913 C  CB  . LEU A 1 426 ? 117.289 115.707 96.375  1.00 96.59 ? 414 LEU A CB  1 
ATOM   2914 C  CG  . LEU A 1 426 ? 115.875 115.158 96.199  1.00 96.59 ? 414 LEU A CG  1 
ATOM   2915 C  CD1 . LEU A 1 426 ? 114.888 115.887 97.095  1.00 96.59 ? 414 LEU A CD1 1 
ATOM   2916 C  CD2 . LEU A 1 426 ? 115.460 115.264 94.742  1.00 96.59 ? 414 LEU A CD2 1 
ATOM   2917 N  N   . VAL A 1 427 ? 120.494 115.883 96.441  1.00 94.59 ? 415 VAL A N   1 
ATOM   2918 C  CA  . VAL A 1 427 ? 121.731 116.632 96.263  1.00 94.59 ? 415 VAL A CA  1 
ATOM   2919 C  C   . VAL A 1 427 ? 122.578 115.966 95.186  1.00 94.59 ? 415 VAL A C   1 
ATOM   2920 O  O   . VAL A 1 427 ? 123.141 116.642 94.340  1.00 94.59 ? 415 VAL A O   1 
ATOM   2921 C  CB  . VAL A 1 427 ? 122.514 116.774 97.587  1.00 94.59 ? 415 VAL A CB  1 
ATOM   2922 C  CG1 . VAL A 1 427 ? 123.965 117.157 97.340  1.00 94.59 ? 415 VAL A CG1 1 
ATOM   2923 C  CG2 . VAL A 1 427 ? 121.843 117.797 98.488  1.00 94.59 ? 415 VAL A CG2 1 
ATOM   2924 N  N   . ASP A 1 428 ? 122.627 114.639 95.180  1.00 93.22 ? 416 ASP A N   1 
ATOM   2925 C  CA  . ASP A 1 428 ? 123.429 113.911 94.197  1.00 93.22 ? 416 ASP A CA  1 
ATOM   2926 C  C   . ASP A 1 428 ? 123.003 114.108 92.742  1.00 93.22 ? 416 ASP A C   1 
ATOM   2927 O  O   . ASP A 1 428 ? 123.849 114.158 91.862  1.00 93.22 ? 416 ASP A O   1 
ATOM   2928 C  CB  . ASP A 1 428 ? 123.468 112.423 94.534  1.00 93.22 ? 416 ASP A CB  1 
ATOM   2929 C  CG  . ASP A 1 428 ? 124.279 112.131 95.777  1.00 93.22 ? 416 ASP A CG  1 
ATOM   2930 O  OD1 . ASP A 1 428 ? 124.932 113.062 96.293  1.00 93.22 ? 416 ASP A OD1 1 
ATOM   2931 O  OD2 . ASP A 1 428 ? 124.264 110.972 96.241  1.00 93.22 ? 416 ASP A OD2 1 
ATOM   2932 N  N   . LEU A 1 429 ? 121.720 114.344 92.508  1.00 93.20 ? 417 LEU A N   1 
ATOM   2933 C  CA  . LEU A 1 429 ? 121.260 114.635 91.154  1.00 93.20 ? 417 LEU A CA  1 
ATOM   2934 C  C   . LEU A 1 429 ? 121.979 115.862 90.605  1.00 93.20 ? 417 LEU A C   1 
ATOM   2935 O  O   . LEU A 1 429 ? 122.320 115.901 89.426  1.00 93.20 ? 417 LEU A O   1 
ATOM   2936 C  CB  . LEU A 1 429 ? 119.748 114.844 91.142  1.00 93.20 ? 417 LEU A CB  1 
ATOM   2937 C  CG  . LEU A 1 429 ? 118.932 113.597 91.462  1.00 93.20 ? 417 LEU A CG  1 
ATOM   2938 C  CD1 . LEU A 1 429 ? 117.449 113.923 91.514  1.00 93.20 ? 417 LEU A CD1 1 
ATOM   2939 C  CD2 . LEU A 1 429 ? 119.218 112.525 90.424  1.00 93.20 ? 417 LEU A CD2 1 
ATOM   2940 N  N   . TYR A 1 430 ? 122.209 116.867 91.446  1.00 92.72 ? 418 TYR A N   1 
ATOM   2941 C  CA  . TYR A 1 430 ? 122.950 118.063 91.025  1.00 92.72 ? 418 TYR A CA  1 
ATOM   2942 C  C   . TYR A 1 430 ? 124.014 118.328 92.070  1.00 92.72 ? 418 TYR A C   1 
ATOM   2943 O  O   . TYR A 1 430 ? 123.900 119.281 92.838  1.00 92.72 ? 418 TYR A O   1 
ATOM   2944 C  CB  . TYR A 1 430 ? 122.013 119.261 90.940  1.00 92.72 ? 418 TYR A CB  1 
ATOM   2945 C  CG  . TYR A 1 430 ? 120.854 119.066 89.995  1.00 92.72 ? 418 TYR A CG  1 
ATOM   2946 C  CD1 . TYR A 1 430 ? 121.022 119.203 88.626  1.00 92.72 ? 418 TYR A CD1 1 
ATOM   2947 C  CD2 . TYR A 1 430 ? 119.590 118.745 90.472  1.00 92.72 ? 418 TYR A CD2 1 
ATOM   2948 C  CE1 . TYR A 1 430 ? 119.965 119.025 87.756  1.00 92.72 ? 418 TYR A CE1 1 
ATOM   2949 C  CE2 . TYR A 1 430 ? 118.528 118.564 89.610  1.00 92.72 ? 418 TYR A CE2 1 
ATOM   2950 C  CZ  . TYR A 1 430 ? 118.721 118.706 88.253  1.00 92.72 ? 418 TYR A CZ  1 
ATOM   2951 O  OH  . TYR A 1 430 ? 117.666 118.529 87.388  1.00 92.72 ? 418 TYR A OH  1 
ATOM   2952 N  N   . PRO A 1 431 ? 125.061 117.489 92.113  1.00 87.33 ? 419 PRO A N   1 
ATOM   2953 C  CA  . PRO A 1 431 ? 126.043 117.624 93.197  1.00 87.33 ? 419 PRO A CA  1 
ATOM   2954 C  C   . PRO A 1 431 ? 126.885 118.887 93.264  1.00 87.33 ? 419 PRO A C   1 
ATOM   2955 O  O   . PRO A 1 431 ? 127.023 119.433 94.348  1.00 87.33 ? 419 PRO A O   1 
ATOM   2956 C  CB  . PRO A 1 431 ? 126.943 116.407 92.995  1.00 87.33 ? 419 PRO A CB  1 
ATOM   2957 C  CG  . PRO A 1 431 ? 126.808 116.038 91.554  1.00 87.33 ? 419 PRO A CG  1 
ATOM   2958 C  CD  . PRO A 1 431 ? 125.580 116.694 90.988  1.00 87.33 ? 419 PRO A CD  1 
ATOM   2959 N  N   . SER A 1 432 ? 127.418 119.367 92.149  1.00 85.92 ? 420 SER A N   1 
ATOM   2960 C  CA  . SER A 1 432 ? 128.316 120.515 92.217  1.00 85.92 ? 420 SER A CA  1 
ATOM   2961 C  C   . SER A 1 432 ? 127.598 121.744 92.735  1.00 85.92 ? 420 SER A C   1 
ATOM   2962 O  O   . SER A 1 432 ? 128.128 122.472 93.568  1.00 85.92 ? 420 SER A O   1 
ATOM   2963 C  CB  . SER A 1 432 ? 128.938 120.800 90.850  1.00 85.92 ? 420 SER A CB  1 
ATOM   2964 O  OG  . SER A 1 432 ? 129.835 121.895 90.922  1.00 85.92 ? 420 SER A OG  1 
ATOM   2965 N  N   . PHE A 1 433 ? 126.384 121.970 92.253  1.00 90.67 ? 421 PHE A N   1 
ATOM   2966 C  CA  . PHE A 1 433 ? 125.604 123.101 92.722  1.00 90.67 ? 421 PHE A CA  1 
ATOM   2967 C  C   . PHE A 1 433 ? 125.246 122.984 94.194  1.00 90.67 ? 421 PHE A C   1 
ATOM   2968 O  O   . PHE A 1 433 ? 125.385 123.945 94.936  1.00 90.67 ? 421 PHE A O   1 
ATOM   2969 C  CB  . PHE A 1 433 ? 124.325 123.209 91.886  1.00 90.67 ? 421 PHE A CB  1 
ATOM   2970 C  CG  . PHE A 1 433 ? 123.502 124.433 92.176  1.00 90.67 ? 421 PHE A CG  1 
ATOM   2971 C  CD1 . PHE A 1 433 ? 123.744 125.617 91.506  1.00 90.67 ? 421 PHE A CD1 1 
ATOM   2972 C  CD2 . PHE A 1 433 ? 122.469 124.392 93.099  1.00 90.67 ? 421 PHE A CD2 1 
ATOM   2973 C  CE1 . PHE A 1 433 ? 122.987 126.744 91.764  1.00 90.67 ? 421 PHE A CE1 1 
ATOM   2974 C  CE2 . PHE A 1 433 ? 121.710 125.514 93.364  1.00 90.67 ? 421 PHE A CE2 1 
ATOM   2975 C  CZ  . PHE A 1 433 ? 121.969 126.692 92.694  1.00 90.67 ? 421 PHE A CZ  1 
ATOM   2976 N  N   . LEU A 1 434 ? 124.792 121.819 94.640  1.00 93.07 ? 422 LEU A N   1 
ATOM   2977 C  CA  . LEU A 1 434 ? 124.338 121.707 96.029  1.00 93.07 ? 422 LEU A CA  1 
ATOM   2978 C  C   . LEU A 1 434 ? 125.392 121.270 97.041  1.00 93.07 ? 422 LEU A C   1 
ATOM   2979 O  O   . LEU A 1 434 ? 125.061 121.004 98.193  1.00 93.07 ? 422 LEU A O   1 
ATOM   2980 C  CB  . LEU A 1 434 ? 123.104 120.813 96.124  1.00 93.07 ? 422 LEU A CB  1 
ATOM   2981 C  CG  . LEU A 1 434 ? 121.792 121.467 95.700  1.00 93.07 ? 422 LEU A CG  1 
ATOM   2982 C  CD1 . LEU A 1 434 ? 120.673 120.440 95.623  1.00 93.07 ? 422 LEU A CD1 1 
ATOM   2983 C  CD2 . LEU A 1 434 ? 121.437 122.589 96.662  1.00 93.07 ? 422 LEU A CD2 1 
ATOM   2984 N  N   . ARG A 1 435 ? 126.654 121.201 96.628  1.00 88.64 ? 423 ARG A N   1 
ATOM   2985 C  CA  . ARG A 1 435 ? 127.722 120.855 97.571  1.00 88.64 ? 423 ARG A CA  1 
ATOM   2986 C  C   . ARG A 1 435 ? 128.421 122.049 98.185  1.00 88.64 ? 423 ARG A C   1 
ATOM   2987 O  O   . ARG A 1 435 ? 129.384 121.882 98.931  1.00 88.64 ? 423 ARG A O   1 
ATOM   2988 C  CB  . ARG A 1 435 ? 128.730 119.862 96.992  1.00 88.64 ? 423 ARG A CB  1 
ATOM   2989 C  CG  . ARG A 1 435 ? 128.267 118.420 97.130  1.00 88.64 ? 423 ARG A CG  1 
ATOM   2990 C  CD  . ARG A 1 435 ? 129.429 117.451 97.258  1.00 88.64 ? 423 ARG A CD  1 
ATOM   2991 N  NE  . ARG A 1 435 ? 128.958 116.094 97.518  1.00 88.64 ? 423 ARG A NE  1 
ATOM   2992 C  CZ  . ARG A 1 435 ? 128.832 115.153 96.588  1.00 88.64 ? 423 ARG A CZ  1 
ATOM   2993 N  NH1 . ARG A 1 435 ? 129.163 115.412 95.331  1.00 88.64 ? 423 ARG A NH1 1 
ATOM   2994 N  NH2 . ARG A 1 435 ? 128.390 113.947 96.917  1.00 88.64 ? 423 ARG A NH2 1 
ATOM   2995 N  N   . LYS A 1 436 ? 127.959 123.255 97.876  1.00 86.98 ? 424 LYS A N   1 
ATOM   2996 C  CA  . LYS A 1 436 ? 128.520 124.432 98.525  1.00 86.98 ? 424 LYS A CA  1 
ATOM   2997 C  C   . LYS A 1 436 ? 128.160 124.260 99.984  1.00 86.98 ? 424 LYS A C   1 
ATOM   2998 O  O   . LYS A 1 436 ? 127.081 123.747 100.292 1.00 86.98 ? 424 LYS A O   1 
ATOM   2999 C  CB  . LYS A 1 436 ? 127.904 125.704 97.961  1.00 86.98 ? 424 LYS A CB  1 
ATOM   3000 C  CG  . LYS A 1 436 ? 128.061 125.848 96.459  1.00 86.98 ? 424 LYS A CG  1 
ATOM   3001 C  CD  . LYS A 1 436 ? 129.513 125.722 96.032  1.00 86.98 ? 424 LYS A CD  1 
ATOM   3002 C  CE  . LYS A 1 436 ? 129.682 126.061 94.561  1.00 86.98 ? 424 LYS A CE  1 
ATOM   3003 N  NZ  . LYS A 1 436 ? 128.783 125.253 93.692  1.00 86.98 ? 424 LYS A NZ  1 
ATOM   3004 N  N   . GLY A 1 437 ? 129.020 124.692 100.899 1.00 87.73 ? 425 GLY A N   1 
ATOM   3005 C  CA  . GLY A 1 437 ? 128.755 124.409 102.301 1.00 87.73 ? 425 GLY A CA  1 
ATOM   3006 C  C   . GLY A 1 437 ? 127.458 124.965 102.838 1.00 87.73 ? 425 GLY A C   1 
ATOM   3007 O  O   . GLY A 1 437 ? 126.724 124.242 103.503 1.00 87.73 ? 425 GLY A O   1 
ATOM   3008 N  N   . TYR A 1 438 ? 127.144 126.220 102.545 1.00 92.40 ? 426 TYR A N   1 
ATOM   3009 C  CA  . TYR A 1 438 ? 125.854 126.769 102.955 1.00 92.40 ? 426 TYR A CA  1 
ATOM   3010 C  C   . TYR A 1 438 ? 124.670 126.148 102.243 1.00 92.40 ? 426 TYR A C   1 
ATOM   3011 O  O   . TYR A 1 438 ? 123.648 125.885 102.860 1.00 92.40 ? 426 TYR A O   1 
ATOM   3012 C  CB  . TYR A 1 438 ? 125.836 128.287 102.805 1.00 92.40 ? 426 TYR A CB  1 
ATOM   3013 C  CG  . TYR A 1 438 ? 126.738 128.977 103.796 1.00 92.40 ? 426 TYR A CG  1 
ATOM   3014 C  CD1 . TYR A 1 438 ? 126.372 129.087 105.130 1.00 92.40 ? 426 TYR A CD1 1 
ATOM   3015 C  CD2 . TYR A 1 438 ? 127.964 129.499 103.406 1.00 92.40 ? 426 TYR A CD2 1 
ATOM   3016 C  CE1 . TYR A 1 438 ? 127.196 129.711 106.046 1.00 92.40 ? 426 TYR A CE1 1 
ATOM   3017 C  CE2 . TYR A 1 438 ? 128.794 130.125 104.315 1.00 92.40 ? 426 TYR A CE2 1 
ATOM   3018 C  CZ  . TYR A 1 438 ? 128.405 130.227 105.634 1.00 92.40 ? 426 TYR A CZ  1 
ATOM   3019 O  OH  . TYR A 1 438 ? 129.228 130.849 106.544 1.00 92.40 ? 426 TYR A OH  1 
ATOM   3020 N  N   . ARG A 1 439 ? 124.804 125.899 100.948 1.00 94.27 ? 427 ARG A N   1 
ATOM   3021 C  CA  . ARG A 1 439 ? 123.669 125.398 100.171 1.00 94.27 ? 427 ARG A CA  1 
ATOM   3022 C  C   . ARG A 1 439 ? 123.046 124.079 100.620 1.00 94.27 ? 427 ARG A C   1 
ATOM   3023 O  O   . ARG A 1 439 ? 121.831 123.932 100.555 1.00 94.27 ? 427 ARG A O   1 
ATOM   3024 C  CB  . ARG A 1 439 ? 124.006 125.365 98.678  1.00 94.27 ? 427 ARG A CB  1 
ATOM   3025 C  CG  . ARG A 1 439 ? 124.125 126.752 98.071  1.00 94.27 ? 427 ARG A CG  1 
ATOM   3026 C  CD  . ARG A 1 439 ? 123.462 126.827 96.706  1.00 94.27 ? 427 ARG A CD  1 
ATOM   3027 N  NE  . ARG A 1 439 ? 124.363 126.439 95.627  1.00 94.27 ? 427 ARG A NE  1 
ATOM   3028 C  CZ  . ARG A 1 439 ? 125.073 127.298 94.902  1.00 94.27 ? 427 ARG A CZ  1 
ATOM   3029 N  NH1 . ARG A 1 439 ? 124.984 128.600 95.136  1.00 94.27 ? 427 ARG A NH1 1 
ATOM   3030 N  NH2 . ARG A 1 439 ? 125.868 126.857 93.938  1.00 94.27 ? 427 ARG A NH2 1 
ATOM   3031 N  N   . ARG A 1 440 ? 123.850 123.118 101.056 1.00 93.64 ? 428 ARG A N   1 
ATOM   3032 C  CA  . ARG A 1 440 ? 123.285 121.877 101.567 1.00 93.64 ? 428 ARG A CA  1 
ATOM   3033 C  C   . ARG A 1 440 ? 122.419 122.133 102.785 1.00 93.64 ? 428 ARG A C   1 
ATOM   3034 O  O   . ARG A 1 440 ? 121.332 121.587 102.888 1.00 93.64 ? 428 ARG A O   1 
ATOM   3035 C  CB  . ARG A 1 440 ? 124.386 120.874 101.912 1.00 93.64 ? 428 ARG A CB  1 
ATOM   3036 C  CG  . ARG A 1 440 ? 123.884 119.464 102.170 1.00 93.64 ? 428 ARG A CG  1 
ATOM   3037 C  CD  . ARG A 1 440 ? 124.304 118.972 103.545 1.00 93.64 ? 428 ARG A CD  1 
ATOM   3038 N  NE  . ARG A 1 440 ? 123.768 117.646 103.838 1.00 93.64 ? 428 ARG A NE  1 
ATOM   3039 C  CZ  . ARG A 1 440 ? 123.911 117.026 105.005 1.00 93.64 ? 428 ARG A CZ  1 
ATOM   3040 N  NH1 . ARG A 1 440 ? 124.570 117.615 105.993 1.00 93.64 ? 428 ARG A NH1 1 
ATOM   3041 N  NH2 . ARG A 1 440 ? 123.389 115.821 105.186 1.00 93.64 ? 428 ARG A NH2 1 
ATOM   3042 N  N   . GLU A 1 441 ? 122.888 122.970 103.703 1.00 95.07 ? 429 GLU A N   1 
ATOM   3043 C  CA  . GLU A 1 441 ? 122.119 123.288 104.906 1.00 95.07 ? 429 GLU A CA  1 
ATOM   3044 C  C   . GLU A 1 441 ? 120.835 124.017 104.549 1.00 95.07 ? 429 GLU A C   1 
ATOM   3045 O  O   . GLU A 1 441 ? 119.787 123.750 105.129 1.00 95.07 ? 429 GLU A O   1 
ATOM   3046 C  CB  . GLU A 1 441 ? 122.958 124.136 105.849 1.00 95.07 ? 429 GLU A CB  1 
ATOM   3047 C  CG  . GLU A 1 441 ? 124.430 123.767 105.840 1.00 95.07 ? 429 GLU A CG  1 
ATOM   3048 C  CD  . GLU A 1 441 ? 125.300 124.867 106.408 1.00 95.07 ? 429 GLU A CD  1 
ATOM   3049 O  OE1 . GLU A 1 441 ? 124.750 125.928 106.770 1.00 95.07 ? 429 GLU A OE1 1 
ATOM   3050 O  OE2 . GLU A 1 441 ? 126.530 124.672 106.492 1.00 95.07 ? 429 GLU A OE2 1 
ATOM   3051 N  N   . ILE A 1 442 ? 120.908 124.941 103.599 1.00 96.80 ? 430 ILE A N   1 
ATOM   3052 C  CA  . ILE A 1 442 ? 119.715 125.652 103.147 1.00 96.80 ? 430 ILE A CA  1 
ATOM   3053 C  C   . ILE A 1 442 ? 118.741 124.672 102.517 1.00 96.80 ? 430 ILE A C   1 
ATOM   3054 O  O   . ILE A 1 442 ? 117.538 124.773 102.725 1.00 96.80 ? 430 ILE A O   1 
ATOM   3055 C  CB  . ILE A 1 442 ? 120.075 126.767 102.146 1.00 96.80 ? 430 ILE A CB  1 
ATOM   3056 C  CG1 . ILE A 1 442 ? 120.908 127.845 102.837 1.00 96.80 ? 430 ILE A CG1 1 
ATOM   3057 C  CG2 . ILE A 1 442 ? 118.830 127.400 101.544 1.00 96.80 ? 430 ILE A CG2 1 
ATOM   3058 C  CD1 . ILE A 1 442 ? 121.414 128.918 101.899 1.00 96.80 ? 430 ILE A CD1 1 
ATOM   3059 N  N   . PHE A 1 443 ? 119.258 123.700 101.775 1.00 97.25 ? 431 PHE A N   1 
ATOM   3060 C  CA  . PHE A 1 443 ? 118.406 122.698 101.154 1.00 97.25 ? 431 PHE A CA  1 
ATOM   3061 C  C   . PHE A 1 443 ? 117.694 121.862 102.207 1.00 97.25 ? 431 PHE A C   1 
ATOM   3062 O  O   . PHE A 1 443 ? 116.517 121.566 102.065 1.00 97.25 ? 431 PHE A O   1 
ATOM   3063 C  CB  . PHE A 1 443 ? 119.227 121.807 100.228 1.00 97.25 ? 431 PHE A CB  1 
ATOM   3064 C  CG  . PHE A 1 443 ? 118.408 120.872 99.395  1.00 97.25 ? 431 PHE A CG  1 
ATOM   3065 C  CD1 . PHE A 1 443 ? 117.576 121.358 98.405  1.00 97.25 ? 431 PHE A CD1 1 
ATOM   3066 C  CD2 . PHE A 1 443 ? 118.490 119.506 99.586  1.00 97.25 ? 431 PHE A CD2 1 
ATOM   3067 C  CE1 . PHE A 1 443 ? 116.825 120.497 97.631  1.00 97.25 ? 431 PHE A CE1 1 
ATOM   3068 C  CE2 . PHE A 1 443 ? 117.744 118.639 98.815  1.00 97.25 ? 431 PHE A CE2 1 
ATOM   3069 C  CZ  . PHE A 1 443 ? 116.911 119.136 97.835  1.00 97.25 ? 431 PHE A CZ  1 
ATOM   3070 N  N   . ILE A 1 444 ? 118.396 121.492 103.273 1.00 97.31 ? 432 ILE A N   1 
ATOM   3071 C  CA  . ILE A 1 444 ? 117.788 120.681 104.314 1.00 97.31 ? 432 ILE A CA  1 
ATOM   3072 C  C   . ILE A 1 444 ? 116.647 121.465 104.924 1.00 97.31 ? 432 ILE A C   1 
ATOM   3073 O  O   . ILE A 1 444 ? 115.565 120.928 105.137 1.00 97.31 ? 432 ILE A O   1 
ATOM   3074 C  CB  . ILE A 1 444 ? 118.797 120.310 105.416 1.00 97.31 ? 432 ILE A CB  1 
ATOM   3075 C  CG1 . ILE A 1 444 ? 119.962 119.519 104.838 1.00 97.31 ? 432 ILE A CG1 1 
ATOM   3076 C  CG2 . ILE A 1 444 ? 118.135 119.478 106.499 1.00 97.31 ? 432 ILE A CG2 1 
ATOM   3077 C  CD1 . ILE A 1 444 ? 121.053 119.248 105.847 1.00 97.31 ? 432 ILE A CD1 1 
ATOM   3078 N  N   . ALA A 1 445 ? 116.867 122.749 105.166 1.00 98.11 ? 433 ALA A N   1 
ATOM   3079 C  CA  . ALA A 1 445 ? 115.831 123.592 105.733 1.00 98.11 ? 433 ALA A CA  1 
ATOM   3080 C  C   . ALA A 1 445 ? 114.646 123.711 104.800 1.00 98.11 ? 433 ALA A C   1 
ATOM   3081 O  O   . ALA A 1 445 ? 113.510 123.662 105.237 1.00 98.11 ? 433 ALA A O   1 
ATOM   3082 C  CB  . ALA A 1 445 ? 116.402 124.959 106.031 1.00 98.11 ? 433 ALA A CB  1 
ATOM   3083 N  N   . PHE A 1 446 ? 114.907 123.863 103.512 1.00 98.07 ? 434 PHE A N   1 
ATOM   3084 C  CA  . PHE A 1 446 ? 113.841 123.980 102.533 1.00 98.07 ? 434 PHE A CA  1 
ATOM   3085 C  C   . PHE A 1 446 ? 112.991 122.721 102.473 1.00 98.07 ? 434 PHE A C   1 
ATOM   3086 O  O   . PHE A 1 446 ? 111.772 122.799 102.457 1.00 98.07 ? 434 PHE A O   1 
ATOM   3087 C  CB  . PHE A 1 446 ? 114.462 124.270 101.164 1.00 98.07 ? 434 PHE A CB  1 
ATOM   3088 C  CG  . PHE A 1 446 ? 113.511 124.142 100.011 1.00 98.07 ? 434 PHE A CG  1 
ATOM   3089 C  CD1 . PHE A 1 446 ? 112.627 125.161 99.709  1.00 98.07 ? 434 PHE A CD1 1 
ATOM   3090 C  CD2 . PHE A 1 446 ? 113.526 123.012 99.208  1.00 98.07 ? 434 PHE A CD2 1 
ATOM   3091 C  CE1 . PHE A 1 446 ? 111.759 125.049 98.641  1.00 98.07 ? 434 PHE A CE1 1 
ATOM   3092 C  CE2 . PHE A 1 446 ? 112.657 122.891 98.143  1.00 98.07 ? 434 PHE A CE2 1 
ATOM   3093 C  CZ  . PHE A 1 446 ? 111.774 123.912 97.857  1.00 98.07 ? 434 PHE A CZ  1 
ATOM   3094 N  N   . VAL A 1 447 ? 113.625 121.556 102.466 1.00 97.95 ? 435 VAL A N   1 
ATOM   3095 C  CA  . VAL A 1 447 ? 112.885 120.312 102.427 1.00 97.95 ? 435 VAL A CA  1 
ATOM   3096 C  C   . VAL A 1 447 ? 112.052 120.147 103.687 1.00 97.95 ? 435 VAL A C   1 
ATOM   3097 O  O   . VAL A 1 447 ? 110.878 119.794 103.618 1.00 97.95 ? 435 VAL A O   1 
ATOM   3098 C  CB  . VAL A 1 447 ? 113.834 119.115 102.233 1.00 97.95 ? 435 VAL A CB  1 
ATOM   3099 C  CG1 . VAL A 1 447 ? 113.109 117.795 102.438 1.00 97.95 ? 435 VAL A CG1 1 
ATOM   3100 C  CG2 . VAL A 1 447 ? 114.468 119.168 100.853 1.00 97.95 ? 435 VAL A CG2 1 
ATOM   3101 N  N   . CYS A 1 448 ? 112.639 120.446 104.839 1.00 98.48 ? 436 CYS A N   1 
ATOM   3102 C  CA  . CYS A 1 448 ? 111.914 120.327 106.094 1.00 98.48 ? 436 CYS A CA  1 
ATOM   3103 C  C   . CYS A 1 448 ? 110.753 121.291 106.177 1.00 98.48 ? 436 CYS A C   1 
ATOM   3104 O  O   . CYS A 1 448 ? 109.674 120.918 106.614 1.00 98.48 ? 436 CYS A O   1 
ATOM   3105 C  CB  . CYS A 1 448 ? 112.861 120.513 107.276 1.00 98.48 ? 436 CYS A CB  1 
ATOM   3106 S  SG  . CYS A 1 448 ? 114.046 119.169 107.500 1.00 98.48 ? 436 CYS A SG  1 
ATOM   3107 N  N   . SER A 1 449 ? 110.966 122.531 105.757 1.00 98.50 ? 437 SER A N   1 
ATOM   3108 C  CA  . SER A 1 449 ? 109.904 123.530 105.762 1.00 98.50 ? 437 SER A CA  1 
ATOM   3109 C  C   . SER A 1 449 ? 108.762 123.226 104.808 1.00 98.50 ? 437 SER A C   1 
ATOM   3110 O  O   . SER A 1 449 ? 107.607 123.399 105.161 1.00 98.50 ? 437 SER A O   1 
ATOM   3111 C  CB  . SER A 1 449 ? 110.473 124.910 105.459 1.00 98.50 ? 437 SER A CB  1 
ATOM   3112 O  OG  . SER A 1 449 ? 110.981 124.974 104.143 1.00 98.50 ? 437 SER A OG  1 
ATOM   3113 N  N   . ILE A 1 450 ? 109.074 122.768 103.605 1.00 98.36 ? 438 ILE A N   1 
ATOM   3114 C  CA  . ILE A 1 450 ? 108.039 122.477 102.625 1.00 98.36 ? 438 ILE A CA  1 
ATOM   3115 C  C   . ILE A 1 450 ? 107.223 121.297 103.101 1.00 98.36 ? 438 ILE A C   1 
ATOM   3116 O  O   . ILE A 1 450 ? 105.997 121.318 103.028 1.00 98.36 ? 438 ILE A O   1 
ATOM   3117 C  CB  . ILE A 1 450 ? 108.630 122.206 101.228 1.00 98.36 ? 438 ILE A CB  1 
ATOM   3118 C  CG1 . ILE A 1 450 ? 109.184 123.497 100.638 1.00 98.36 ? 438 ILE A CG1 1 
ATOM   3119 C  CG2 . ILE A 1 450 ? 107.582 121.644 100.283 1.00 98.36 ? 438 ILE A CG2 1 
ATOM   3120 C  CD1 . ILE A 1 450 ? 108.150 124.589 100.480 1.00 98.36 ? 438 ILE A CD1 1 
ATOM   3121 N  N   . SER A 1 451 ? 107.896 120.277 103.617 1.00 98.30 ? 439 SER A N   1 
ATOM   3122 C  CA  . SER A 1 451 ? 107.193 119.116 104.143 1.00 98.30 ? 439 SER A CA  1 
ATOM   3123 C  C   . SER A 1 451 ? 106.358 119.463 105.368 1.00 98.30 ? 439 SER A C   1 
ATOM   3124 O  O   . SER A 1 451 ? 105.305 118.875 105.579 1.00 98.30 ? 439 SER A O   1 
ATOM   3125 C  CB  . SER A 1 451 ? 108.176 117.999 104.432 1.00 98.30 ? 439 SER A CB  1 
ATOM   3126 O  OG  . SER A 1 451 ? 108.913 117.656 103.275 1.00 98.30 ? 439 SER A OG  1 
ATOM   3127 N  N   . TYR A 1 452 ? 106.809 120.413 106.179 1.00 98.68 ? 440 TYR A N   1 
ATOM   3128 C  CA  . TYR A 1 452 ? 106.012 120.855 107.320 1.00 98.68 ? 440 TYR A CA  1 
ATOM   3129 C  C   . TYR A 1 452 ? 104.710 121.500 106.877 1.00 98.68 ? 440 TYR A C   1 
ATOM   3130 O  O   . TYR A 1 452 ? 103.666 121.241 107.459 1.00 98.68 ? 440 TYR A O   1 
ATOM   3131 C  CB  . TYR A 1 452 ? 106.817 121.816 108.187 1.00 98.68 ? 440 TYR A CB  1 
ATOM   3132 C  CG  . TYR A 1 452 ? 106.018 122.512 109.261 1.00 98.68 ? 440 TYR A CG  1 
ATOM   3133 C  CD1 . TYR A 1 452 ? 105.523 121.811 110.344 1.00 98.68 ? 440 TYR A CD1 1 
ATOM   3134 C  CD2 . TYR A 1 452 ? 105.773 123.876 109.197 1.00 98.68 ? 440 TYR A CD2 1 
ATOM   3135 C  CE1 . TYR A 1 452 ? 104.791 122.442 111.326 1.00 98.68 ? 440 TYR A CE1 1 
ATOM   3136 C  CE2 . TYR A 1 452 ? 105.044 124.515 110.177 1.00 98.68 ? 440 TYR A CE2 1 
ATOM   3137 C  CZ  . TYR A 1 452 ? 104.558 123.791 111.241 1.00 98.68 ? 440 TYR A CZ  1 
ATOM   3138 O  OH  . TYR A 1 452 ? 103.830 124.417 112.224 1.00 98.68 ? 440 TYR A OH  1 
ATOM   3139 N  N   . LEU A 1 453 ? 104.762 122.345 105.853 1.00 98.62 ? 441 LEU A N   1 
ATOM   3140 C  CA  . LEU A 1 453 ? 103.571 123.014 105.346 1.00 98.62 ? 441 LEU A CA  1 
ATOM   3141 C  C   . LEU A 1 453 ? 102.571 122.036 104.753 1.00 98.62 ? 441 LEU A C   1 
ATOM   3142 O  O   . LEU A 1 453 ? 101.367 122.182 104.944 1.00 98.62 ? 441 LEU A O   1 
ATOM   3143 C  CB  . LEU A 1 453 ? 103.978 124.055 104.315 1.00 98.62 ? 441 LEU A CB  1 
ATOM   3144 C  CG  . LEU A 1 453 ? 104.882 125.182 104.815 1.00 98.62 ? 441 LEU A CG  1 
ATOM   3145 C  CD1 . LEU A 1 453 ? 105.479 125.960 103.654 1.00 98.62 ? 441 LEU A CD1 1 
ATOM   3146 C  CD2 . LEU A 1 453 ? 104.144 126.105 105.769 1.00 98.62 ? 441 LEU A CD2 1 
ATOM   3147 N  N   . LEU A 1 454 ? 103.047 121.043 104.018 1.00 98.10 ? 442 LEU A N   1 
ATOM   3148 C  CA  . LEU A 1 454 ? 102.155 120.013 103.500 1.00 98.10 ? 442 LEU A CA  1 
ATOM   3149 C  C   . LEU A 1 454 ? 101.556 119.246 104.661 1.00 98.10 ? 442 LEU A C   1 
ATOM   3150 O  O   . LEU A 1 454 ? 100.400 118.860 104.610 1.00 98.10 ? 442 LEU A O   1 
ATOM   3151 C  CB  . LEU A 1 454 ? 102.896 119.091 102.548 1.00 98.10 ? 442 LEU A CB  1 
ATOM   3152 C  CG  . LEU A 1 454 ? 103.366 119.725 101.244 1.00 98.10 ? 442 LEU A CG  1 
ATOM   3153 C  CD1 . LEU A 1 454 ? 104.316 118.792 100.514 1.00 98.10 ? 442 LEU A CD1 1 
ATOM   3154 C  CD2 . LEU A 1 454 ? 102.164 120.063 100.378 1.00 98.10 ? 442 LEU A CD2 1 
ATOM   3155 N  N   . GLY A 1 455 ? 102.339 119.013 105.707 1.00 98.42 ? 443 GLY A N   1 
ATOM   3156 C  CA  . GLY A 1 455 ? 101.853 118.334 106.895 1.00 98.42 ? 443 GLY A CA  1 
ATOM   3157 C  C   . GLY A 1 455 ? 100.773 119.131 107.574 1.00 98.42 ? 443 GLY A C   1 
ATOM   3158 O  O   . GLY A 1 455 ? 99.946  118.562 108.269 1.00 98.42 ? 443 GLY A O   1 
ATOM   3159 N  N   . LEU A 1 456 ? 100.789 120.447 107.409 1.00 98.60 ? 444 LEU A N   1 
ATOM   3160 C  CA  . LEU A 1 456 ? 99.764  121.310 107.988 1.00 98.60 ? 444 LEU A CA  1 
ATOM   3161 C  C   . LEU A 1 456 ? 98.379  120.977 107.451 1.00 98.60 ? 444 LEU A C   1 
ATOM   3162 O  O   . LEU A 1 456 ? 97.388  121.132 108.151 1.00 98.60 ? 444 LEU A O   1 
ATOM   3163 C  CB  . LEU A 1 456 ? 100.095 122.791 107.812 1.00 98.60 ? 444 LEU A CB  1 
ATOM   3164 C  CG  . LEU A 1 456 ? 101.284 123.350 108.589 1.00 98.60 ? 444 LEU A CG  1 
ATOM   3165 C  CD1 . LEU A 1 456 ? 101.423 124.840 108.336 1.00 98.60 ? 444 LEU A CD1 1 
ATOM   3166 C  CD2 . LEU A 1 456 ? 101.125 123.078 110.072 1.00 98.60 ? 444 LEU A CD2 1 
ATOM   3167 N  N   . THR A 1 457 ? 98.295  120.541 106.204 1.00 97.55 ? 445 THR A N   1 
ATOM   3168 C  CA  . THR A 1 457 ? 97.008  120.114 105.656 1.00 97.55 ? 445 THR A CA  1 
ATOM   3169 C  C   . THR A 1 457 ? 96.459  118.936 106.447 1.00 97.55 ? 445 THR A C   1 
ATOM   3170 O  O   . THR A 1 457 ? 95.255  118.783 106.569 1.00 97.55 ? 445 THR A O   1 
ATOM   3171 C  CB  . THR A 1 457 ? 97.102  119.746 104.171 1.00 97.55 ? 445 THR A CB  1 
ATOM   3172 O  OG1 . THR A 1 457 ? 97.841  118.528 104.019 1.00 97.55 ? 445 THR A OG1 1 
ATOM   3173 C  CG2 . THR A 1 457 ? 97.780  120.858 103.390 1.00 97.55 ? 445 THR A CG2 1 
ATOM   3174 N  N   . MET A 1 458 ? 97.331  118.166 107.088 1.00 97.88 ? 446 MET A N   1 
ATOM   3175 C  CA  . MET A 1 458 ? 96.910  117.006 107.878 1.00 97.88 ? 446 MET A CA  1 
ATOM   3176 C  C   . MET A 1 458 ? 96.741  117.248 109.374 1.00 97.88 ? 446 MET A C   1 
ATOM   3177 O  O   . MET A 1 458 ? 96.253  116.377 110.082 1.00 97.88 ? 446 MET A O   1 
ATOM   3178 C  CB  . MET A 1 458 ? 97.878  115.848 107.664 1.00 97.88 ? 446 MET A CB  1 
ATOM   3179 C  CG  . MET A 1 458 ? 97.685  115.107 106.359 1.00 97.88 ? 446 MET A CG  1 
ATOM   3180 S  SD  . MET A 1 458 ? 99.106  114.082 105.964 1.00 97.88 ? 446 MET A SD  1 
ATOM   3181 C  CE  . MET A 1 458 ? 100.111 115.259 105.076 1.00 97.88 ? 446 MET A CE  1 
ATOM   3182 N  N   . VAL A 1 459 ? 97.151  118.407 109.871 1.00 98.16 ? 447 VAL A N   1 
ATOM   3183 C  CA  . VAL A 1 459 ? 96.944  118.731 111.287 1.00 98.16 ? 447 VAL A CA  1 
ATOM   3184 C  C   . VAL A 1 459 ? 95.735  119.628 111.472 1.00 98.16 ? 447 VAL A C   1 
ATOM   3185 O  O   . VAL A 1 459 ? 95.495  120.127 112.563 1.00 98.16 ? 447 VAL A O   1 
ATOM   3186 C  CB  . VAL A 1 459 ? 98.205  119.272 111.996 1.00 98.16 ? 447 VAL A CB  1 
ATOM   3187 C  CG1 . VAL A 1 459 ? 99.280  118.201 112.061 1.00 98.16 ? 447 VAL A CG1 1 
ATOM   3188 C  CG2 . VAL A 1 459 ? 98.726  120.519 111.324 1.00 98.16 ? 447 VAL A CG2 1 
ATOM   3189 N  N   . THR A 1 460 ? 94.978  119.847 110.407 1.00 98.33 ? 448 THR A N   1 
ATOM   3190 C  CA  . THR A 1 460 ? 93.742  120.614 110.505 1.00 98.33 ? 448 THR A CA  1 
ATOM   3191 C  C   . THR A 1 460 ? 92.685  119.689 111.075 1.00 98.33 ? 448 THR A C   1 
ATOM   3192 O  O   . THR A 1 460 ? 92.920  118.498 111.223 1.00 98.33 ? 448 THR A O   1 
ATOM   3193 C  CB  . THR A 1 460 ? 93.270  121.141 109.139 1.00 98.33 ? 448 THR A CB  1 
ATOM   3194 O  OG1 . THR A 1 460 ? 93.137  120.052 108.220 1.00 98.33 ? 448 THR A OG1 1 
ATOM   3195 C  CG2 . THR A 1 460 ? 94.248  122.145 108.579 1.00 98.33 ? 448 THR A CG2 1 
ATOM   3196 N  N   . GLU A 1 461 ? 91.502  120.210 111.366 1.00 98.05 ? 449 GLU A N   1 
ATOM   3197 C  CA  . GLU A 1 461 ? 90.423  119.389 111.906 1.00 98.05 ? 449 GLU A CA  1 
ATOM   3198 C  C   . GLU A 1 461 ? 89.966  118.281 110.951 1.00 98.05 ? 449 GLU A C   1 
ATOM   3199 O  O   . GLU A 1 461 ? 89.506  117.240 111.396 1.00 98.05 ? 449 GLU A O   1 
ATOM   3200 C  CB  . GLU A 1 461 ? 89.258  120.274 112.328 1.00 98.05 ? 449 GLU A CB  1 
ATOM   3201 C  CG  . GLU A 1 461 ? 89.604  121.238 113.441 1.00 98.05 ? 449 GLU A CG  1 
ATOM   3202 C  CD  . GLU A 1 461 ? 88.422  122.081 113.856 1.00 98.05 ? 449 GLU A CD  1 
ATOM   3203 O  OE1 . GLU A 1 461 ? 88.550  122.844 114.834 1.00 98.05 ? 449 GLU A OE1 1 
ATOM   3204 O  OE2 . GLU A 1 461 ? 87.363  121.975 113.204 1.00 98.05 ? 449 GLU A OE2 1 
ATOM   3205 N  N   . GLY A 1 462 ? 90.103  118.487 109.648 1.00 97.13 ? 450 GLY A N   1 
ATOM   3206 C  CA  . GLY A 1 462 ? 89.742  117.481 108.661 1.00 97.13 ? 450 GLY A CA  1 
ATOM   3207 C  C   . GLY A 1 462 ? 90.989  116.806 108.153 1.00 97.13 ? 450 GLY A C   1 
ATOM   3208 O  O   . GLY A 1 462 ? 90.954  116.133 107.132 1.00 97.13 ? 450 GLY A O   1 
ATOM   3209 N  N   . GLY A 1 463 ? 92.097  116.961 108.860 1.00 97.31 ? 451 GLY A N   1 
ATOM   3210 C  CA  . GLY A 1 463 ? 93.355  116.412 108.401 1.00 97.31 ? 451 GLY A CA  1 
ATOM   3211 C  C   . GLY A 1 463 ? 93.546  114.923 108.510 1.00 97.31 ? 451 GLY A C   1 
ATOM   3212 O  O   . GLY A 1 463 ? 94.419  114.374 107.857 1.00 97.31 ? 451 GLY A O   1 
ATOM   3213 N  N   . MET A 1 464 ? 92.755  114.257 109.336 1.00 95.30 ? 452 MET A N   1 
ATOM   3214 C  CA  . MET A 1 464 ? 92.832  112.812 109.432 1.00 95.30 ? 452 MET A CA  1 
ATOM   3215 C  C   . MET A 1 464 ? 92.450  112.210 108.104 1.00 95.30 ? 452 MET A C   1 
ATOM   3216 O  O   . MET A 1 464 ? 93.032  111.228 107.668 1.00 95.30 ? 452 MET A O   1 
ATOM   3217 C  CB  . MET A 1 464 ? 91.895  112.315 110.514 1.00 95.30 ? 452 MET A CB  1 
ATOM   3218 C  CG  . MET A 1 464 ? 91.849  110.812 110.711 1.00 95.30 ? 452 MET A CG  1 
ATOM   3219 S  SD  . MET A 1 464 ? 93.279  110.111 111.550 1.00 95.30 ? 452 MET A SD  1 
ATOM   3220 C  CE  . MET A 1 464 ? 94.085  109.305 110.181 1.00 95.30 ? 452 MET A CE  1 
ATOM   3221 N  N   . TYR A 1 465 ? 91.474  112.807 107.447 1.00 96.21 ? 453 TYR A N   1 
ATOM   3222 C  CA  . TYR A 1 465 ? 91.030  112.318 106.162 1.00 96.21 ? 453 TYR A CA  1 
ATOM   3223 C  C   . TYR A 1 465 ? 92.136  112.436 105.144 1.00 96.21 ? 453 TYR A C   1 
ATOM   3224 O  O   . TYR A 1 465 ? 92.349  111.529 104.351 1.00 96.21 ? 453 TYR A O   1 
ATOM   3225 C  CB  . TYR A 1 465 ? 89.815  113.112 105.733 1.00 96.21 ? 453 TYR A CB  1 
ATOM   3226 C  CG  . TYR A 1 465 ? 88.644  112.987 106.668 1.00 96.21 ? 453 TYR A CG  1 
ATOM   3227 C  CD1 . TYR A 1 465 ? 87.895  111.828 106.711 1.00 96.21 ? 453 TYR A CD1 1 
ATOM   3228 C  CD2 . TYR A 1 465 ? 88.283  114.029 107.504 1.00 96.21 ? 453 TYR A CD2 1 
ATOM   3229 C  CE1 . TYR A 1 465 ? 86.817  111.708 107.561 1.00 96.21 ? 453 TYR A CE1 1 
ATOM   3230 C  CE2 . TYR A 1 465 ? 87.208  113.918 108.357 1.00 96.21 ? 453 TYR A CE2 1 
ATOM   3231 C  CZ  . TYR A 1 465 ? 86.478  112.752 108.380 1.00 96.21 ? 453 TYR A CZ  1 
ATOM   3232 O  OH  . TYR A 1 465 ? 85.404  112.624 109.226 1.00 96.21 ? 453 TYR A OH  1 
ATOM   3233 N  N   . VAL A 1 466 ? 92.865  113.540 105.168 1.00 97.05 ? 454 VAL A N   1 
ATOM   3234 C  CA  . VAL A 1 466 ? 93.976  113.728 104.248 1.00 97.05 ? 454 VAL A CA  1 
ATOM   3235 C  C   . VAL A 1 466 ? 95.065  112.724 104.563 1.00 97.05 ? 454 VAL A C   1 
ATOM   3236 O  O   . VAL A 1 466 ? 95.710  112.210 103.661 1.00 97.05 ? 454 VAL A O   1 
ATOM   3237 C  CB  . VAL A 1 466 ? 94.525  115.164 104.323 1.00 97.05 ? 454 VAL A CB  1 
ATOM   3238 C  CG1 . VAL A 1 466 ? 95.437  115.456 103.143 1.00 97.05 ? 454 VAL A CG1 1 
ATOM   3239 C  CG2 . VAL A 1 466 ? 93.383  116.164 104.360 1.00 97.05 ? 454 VAL A CG2 1 
ATOM   3240 N  N   . PHE A 1 467 ? 95.273  112.437 105.842 1.00 96.33 ? 455 PHE A N   1 
ATOM   3241 C  CA  . PHE A 1 467 ? 96.271  111.457 106.255 1.00 96.33 ? 455 PHE A CA  1 
ATOM   3242 C  C   . PHE A 1 467 ? 95.944  110.062 105.765 1.00 96.33 ? 455 PHE A C   1 
ATOM   3243 O  O   . PHE A 1 467 ? 96.823  109.347 105.314 1.00 96.33 ? 455 PHE A O   1 
ATOM   3244 C  CB  . PHE A 1 467 ? 96.396  111.455 107.777 1.00 96.33 ? 455 PHE A CB  1 
ATOM   3245 C  CG  . PHE A 1 467 ? 97.468  110.549 108.293 1.00 96.33 ? 455 PHE A CG  1 
ATOM   3246 C  CD1 . PHE A 1 467 ? 98.753  111.016 108.463 1.00 96.33 ? 455 PHE A CD1 1 
ATOM   3247 C  CD2 . PHE A 1 467 ? 97.192  109.230 108.602 1.00 96.33 ? 455 PHE A CD2 1 
ATOM   3248 C  CE1 . PHE A 1 467 ? 99.740  110.183 108.932 1.00 96.33 ? 455 PHE A CE1 1 
ATOM   3249 C  CE2 . PHE A 1 467 ? 98.176  108.394 109.064 1.00 96.33 ? 455 PHE A CE2 1 
ATOM   3250 C  CZ  . PHE A 1 467 ? 99.452  108.872 109.228 1.00 96.33 ? 455 PHE A CZ  1 
ATOM   3251 N  N   . GLN A 1 468 ? 94.683  109.669 105.851 1.00 93.81 ? 456 GLN A N   1 
ATOM   3252 C  CA  . GLN A 1 468 ? 94.271  108.371 105.363 1.00 93.81 ? 456 GLN A CA  1 
ATOM   3253 C  C   . GLN A 1 468 ? 94.480  108.272 103.860 1.00 93.81 ? 456 GLN A C   1 
ATOM   3254 O  O   . GLN A 1 468 ? 94.911  107.235 103.372 1.00 93.81 ? 456 GLN A O   1 
ATOM   3255 C  CB  . GLN A 1 468 ? 92.830  108.063 105.769 1.00 93.81 ? 456 GLN A CB  1 
ATOM   3256 C  CG  . GLN A 1 468 ? 92.251  106.787 105.176 1.00 93.81 ? 456 GLN A CG  1 
ATOM   3257 C  CD  . GLN A 1 468 ? 92.845  105.524 105.768 1.00 93.81 ? 456 GLN A CD  1 
ATOM   3258 O  OE1 . GLN A 1 468 ? 92.276  104.939 106.681 1.00 93.81 ? 456 GLN A OE1 1 
ATOM   3259 N  NE2 . GLN A 1 468 ? 93.983  105.088 105.240 1.00 93.81 ? 456 GLN A NE2 1 
ATOM   3260 N  N   . LEU A 1 469 ? 94.210  109.342 103.116 1.00 94.95 ? 457 LEU A N   1 
ATOM   3261 C  CA  . LEU A 1 469 ? 94.483  109.319 101.685 1.00 94.95 ? 457 LEU A CA  1 
ATOM   3262 C  C   . LEU A 1 469 ? 95.959  109.123 101.429 1.00 94.95 ? 457 LEU A C   1 
ATOM   3263 O  O   . LEU A 1 469 ? 96.339  108.343 100.575 1.00 94.95 ? 457 LEU A O   1 
ATOM   3264 C  CB  . LEU A 1 469 ? 94.055  110.626 101.027 1.00 94.95 ? 457 LEU A CB  1 
ATOM   3265 C  CG  . LEU A 1 469 ? 92.659  110.798 100.440 1.00 94.95 ? 457 LEU A CG  1 
ATOM   3266 C  CD1 . LEU A 1 469 ? 92.559  112.191 99.848  1.00 94.95 ? 457 LEU A CD1 1 
ATOM   3267 C  CD2 . LEU A 1 469 ? 92.384  109.758 99.370  1.00 94.95 ? 457 LEU A CD2 1 
ATOM   3268 N  N   . PHE A 1 470 ? 96.798  109.821 102.175 1.00 94.99 ? 458 PHE A N   1 
ATOM   3269 C  CA  . PHE A 1 470 ? 98.237  109.698 102.018 1.00 94.99 ? 458 PHE A CA  1 
ATOM   3270 C  C   . PHE A 1 470 ? 98.737  108.315 102.366 1.00 94.99 ? 458 PHE A C   1 
ATOM   3271 O  O   . PHE A 1 470 ? 99.584  107.775 101.674 1.00 94.99 ? 458 PHE A O   1 
ATOM   3272 C  CB  . PHE A 1 470 ? 98.926  110.726 102.912 1.00 94.99 ? 458 PHE A CB  1 
ATOM   3273 C  CG  . PHE A 1 470 ? 99.364  111.966 102.194 1.00 94.99 ? 458 PHE A CG  1 
ATOM   3274 C  CD1 . PHE A 1 470 ? 98.460  112.968 101.900 1.00 94.99 ? 458 PHE A CD1 1 
ATOM   3275 C  CD2 . PHE A 1 470 ? 100.687 112.135 101.829 1.00 94.99 ? 458 PHE A CD2 1 
ATOM   3276 C  CE1 . PHE A 1 470 ? 98.864  114.111 101.243 1.00 94.99 ? 458 PHE A CE1 1 
ATOM   3277 C  CE2 . PHE A 1 470 ? 101.100 113.275 101.172 1.00 94.99 ? 458 PHE A CE2 1 
ATOM   3278 C  CZ  . PHE A 1 470 ? 100.187 114.265 100.879 1.00 94.99 ? 458 PHE A CZ  1 
ATOM   3279 N  N   . ASP A 1 471 ? 98.234  107.745 103.451 1.00 91.51 ? 459 ASP A N   1 
ATOM   3280 C  CA  . ASP A 1 471 ? 98.637  106.409 103.855 1.00 91.51 ? 459 ASP A CA  1 
ATOM   3281 C  C   . ASP A 1 471 ? 98.212  105.367 102.836 1.00 91.51 ? 459 ASP A C   1 
ATOM   3282 O  O   . ASP A 1 471 ? 98.989  104.491 102.486 1.00 91.51 ? 459 ASP A O   1 
ATOM   3283 C  CB  . ASP A 1 471 ? 98.048  106.093 105.225 1.00 91.51 ? 459 ASP A CB  1 
ATOM   3284 C  CG  . ASP A 1 471 ? 98.891  105.125 106.015 1.00 91.51 ? 459 ASP A CG  1 
ATOM   3285 O  OD1 . ASP A 1 471 ? 100.023 104.822 105.592 1.00 91.51 ? 459 ASP A OD1 1 
ATOM   3286 O  OD2 . ASP A 1 471 ? 98.418  104.669 107.071 1.00 91.51 ? 459 ASP A OD2 1 
ATOM   3287 N  N   . TYR A 1 472 ? 96.984  105.454 102.355 1.00 91.27 ? 460 TYR A N   1 
ATOM   3288 C  CA  . TYR A 1 472 ? 96.498  104.538 101.331 1.00 91.27 ? 460 TYR A CA  1 
ATOM   3289 C  C   . TYR A 1 472 ? 97.151  104.690 99.973  1.00 91.27 ? 460 TYR A C   1 
ATOM   3290 O  O   . TYR A 1 472 ? 97.407  103.697 99.307  1.00 91.27 ? 460 TYR A O   1 
ATOM   3291 C  CB  . TYR A 1 472 ? 94.981  104.694 101.210 1.00 91.27 ? 460 TYR A CB  1 
ATOM   3292 C  CG  . TYR A 1 472 ? 94.267  103.621 100.431 1.00 91.27 ? 460 TYR A CG  1 
ATOM   3293 C  CD1 . TYR A 1 472 ? 93.883  102.436 101.033 1.00 91.27 ? 460 TYR A CD1 1 
ATOM   3294 C  CD2 . TYR A 1 472 ? 93.945  103.809 99.102  1.00 91.27 ? 460 TYR A CD2 1 
ATOM   3295 C  CE1 . TYR A 1 472 ? 93.216  101.461 100.323 1.00 91.27 ? 460 TYR A CE1 1 
ATOM   3296 C  CE2 . TYR A 1 472 ? 93.281  102.845 98.384  1.00 91.27 ? 460 TYR A CE2 1 
ATOM   3297 C  CZ  . TYR A 1 472 ? 92.918  101.675 98.999  1.00 91.27 ? 460 TYR A CZ  1 
ATOM   3298 O  OH  . TYR A 1 472 ? 92.251  100.721 98.275  1.00 91.27 ? 460 TYR A OH  1 
ATOM   3299 N  N   . TYR A 1 473 ? 97.424  105.918 99.548  1.00 93.56 ? 461 TYR A N   1 
ATOM   3300 C  CA  . TYR A 1 473 ? 97.921  106.149 98.189  1.00 93.56 ? 461 TYR A CA  1 
ATOM   3301 C  C   . TYR A 1 473 ? 99.347  106.625 97.970  1.00 93.56 ? 461 TYR A C   1 
ATOM   3302 O  O   . TYR A 1 473 ? 100.002 106.160 97.047  1.00 93.56 ? 461 TYR A O   1 
ATOM   3303 C  CB  . TYR A 1 473 ? 97.020  107.169 97.504  1.00 93.56 ? 461 TYR A CB  1 
ATOM   3304 C  CG  . TYR A 1 473 ? 95.643  106.692 97.107  1.00 93.56 ? 461 TYR A CG  1 
ATOM   3305 C  CD1 . TYR A 1 473 ? 95.461  105.877 95.998  1.00 93.56 ? 461 TYR A CD1 1 
ATOM   3306 C  CD2 . TYR A 1 473 ? 94.519  107.101 97.808  1.00 93.56 ? 461 TYR A CD2 1 
ATOM   3307 C  CE1 . TYR A 1 473 ? 94.201  105.460 95.619  1.00 93.56 ? 461 TYR A CE1 1 
ATOM   3308 C  CE2 . TYR A 1 473 ? 93.256  106.693 97.433  1.00 93.56 ? 461 TYR A CE2 1 
ATOM   3309 C  CZ  . TYR A 1 473 ? 93.103  105.872 96.340  1.00 93.56 ? 461 TYR A CZ  1 
ATOM   3310 O  OH  . TYR A 1 473 ? 91.845  105.460 95.973  1.00 93.56 ? 461 TYR A OH  1 
ATOM   3311 N  N   . ALA A 1 474 ? 99.834  107.561 98.772  1.00 92.46 ? 462 ALA A N   1 
ATOM   3312 C  CA  . ALA A 1 474 ? 101.161 108.138 98.502  1.00 92.46 ? 462 ALA A CA  1 
ATOM   3313 C  C   . ALA A 1 474 ? 102.397 107.257 98.565  1.00 92.46 ? 462 ALA A C   1 
ATOM   3314 O  O   . ALA A 1 474 ? 103.245 107.316 97.680  1.00 92.46 ? 462 ALA A O   1 
ATOM   3315 C  CB  . ALA A 1 474 ? 101.369 109.359 99.385  1.00 92.46 ? 462 ALA A CB  1 
ATOM   3316 N  N   . ALA A 1 475 ? 102.513 106.455 99.610  1.00 84.74 ? 463 ALA A N   1 
ATOM   3317 C  CA  . ALA A 1 475 ? 103.666 105.582 99.758  1.00 84.74 ? 463 ALA A CA  1 
ATOM   3318 C  C   . ALA A 1 475 ? 103.270 104.132 99.912  1.00 84.74 ? 463 ALA A C   1 
ATOM   3319 O  O   . ALA A 1 475 ? 104.066 103.327 100.364 1.00 84.74 ? 463 ALA A O   1 
ATOM   3320 C  CB  . ALA A 1 475 ? 104.523 106.023 100.921 1.00 84.74 ? 463 ALA A CB  1 
ATOM   3321 N  N   . SER A 1 476 ? 102.031 103.805 99.583  1.00 82.92 ? 464 SER A N   1 
ATOM   3322 C  CA  . SER A 1 476 ? 101.549 102.446 99.731  1.00 82.92 ? 464 SER A CA  1 
ATOM   3323 C  C   . SER A 1 476 ? 100.565 102.114 98.653  1.00 82.92 ? 464 SER A C   1 
ATOM   3324 O  O   . SER A 1 476 ? 100.007 103.002 98.025  1.00 82.92 ? 464 SER A O   1 
ATOM   3325 C  CB  . SER A 1 476 ? 100.875 102.254 101.083 1.00 82.92 ? 464 SER A CB  1 
ATOM   3326 O  OG  . SER A 1 476 ? 101.811 102.349 102.139 1.00 82.92 ? 464 SER A OG  1 
ATOM   3327 N  N   . GLY A 1 477 ? 100.352 100.834 98.414  1.00 83.44 ? 465 GLY A N   1 
ATOM   3328 C  CA  . GLY A 1 477 ? 99.352  100.434 97.459  1.00 83.44 ? 465 GLY A CA  1 
ATOM   3329 C  C   . GLY A 1 477 ? 99.914  100.214 96.099  1.00 83.44 ? 465 GLY A C   1 
ATOM   3330 O  O   . GLY A 1 477 ? 100.961 99.602  95.957  1.00 83.44 ? 465 GLY A O   1 
ATOM   3331 N  N   . VAL A 1 478 ? 99.200  100.672 95.086  1.00 88.08 ? 466 VAL A N   1 
ATOM   3332 C  CA  . VAL A 1 478 ? 99.621  100.431 93.724  1.00 88.08 ? 466 VAL A CA  1 
ATOM   3333 C  C   . VAL A 1 478 ? 100.978 101.027 93.393  1.00 88.08 ? 466 VAL A C   1 
ATOM   3334 O  O   . VAL A 1 478 ? 101.692 100.480 92.572  1.00 88.08 ? 466 VAL A O   1 
ATOM   3335 C  CB  . VAL A 1 478 ? 98.552  100.909 92.734  1.00 88.08 ? 466 VAL A CB  1 
ATOM   3336 C  CG1 . VAL A 1 478 ? 97.345  99.989  92.793  1.00 88.08 ? 466 VAL A CG1 1 
ATOM   3337 C  CG2 . VAL A 1 478 ? 98.143  102.334 93.060  1.00 88.08 ? 466 VAL A CG2 1 
ATOM   3338 N  N   . CYS A 1 479 ? 101.339 102.137 94.024  1.00 93.14 ? 467 CYS A N   1 
ATOM   3339 C  CA  . CYS A 1 479 ? 102.647 102.724 93.785  1.00 93.14 ? 467 CYS A CA  1 
ATOM   3340 C  C   . CYS A 1 479 ? 103.779 101.809 94.225  1.00 93.14 ? 467 CYS A C   1 
ATOM   3341 O  O   . CYS A 1 479 ? 104.762 101.659 93.512  1.00 93.14 ? 467 CYS A O   1 
ATOM   3342 C  CB  . CYS A 1 479 ? 102.762 104.094 94.450  1.00 93.14 ? 467 CYS A CB  1 
ATOM   3343 S  SG  . CYS A 1 479 ? 102.678 104.111 96.249  1.00 93.14 ? 467 CYS A SG  1 
ATOM   3344 N  N   . LEU A 1 480 ? 103.651 101.191 95.392  1.00 93.13 ? 468 LEU A N   1 
ATOM   3345 C  CA  . LEU A 1 480 ? 104.663 100.249 95.848  1.00 93.13 ? 468 LEU A CA  1 
ATOM   3346 C  C   . LEU A 1 480 ? 104.717 99.020  94.977  1.00 93.13 ? 468 LEU A C   1 
ATOM   3347 O  O   . LEU A 1 480 ? 105.792 98.536  94.658  1.00 93.13 ? 468 LEU A O   1 
ATOM   3348 C  CB  . LEU A 1 480 ? 104.462 99.871  97.313  1.00 93.13 ? 468 LEU A CB  1 
ATOM   3349 C  CG  . LEU A 1 480 ? 104.870 100.930 98.329  1.00 93.13 ? 468 LEU A CG  1 
ATOM   3350 C  CD1 . LEU A 1 480 ? 105.010 100.296 99.701  1.00 93.13 ? 468 LEU A CD1 1 
ATOM   3351 C  CD2 . LEU A 1 480 ? 106.169 101.604 97.924  1.00 93.13 ? 468 LEU A CD2 1 
ATOM   3352 N  N   . LEU A 1 481 ? 103.558 98.518  94.581  1.00 91.23 ? 469 LEU A N   1 
ATOM   3353 C  CA  . LEU A 1 481 ? 103.504 97.353  93.713  1.00 91.23 ? 469 LEU A CA  1 
ATOM   3354 C  C   . LEU A 1 481 ? 104.146 97.678  92.386  1.00 91.23 ? 469 LEU A C   1 
ATOM   3355 O  O   . LEU A 1 481 ? 104.859 96.860  91.833  1.00 91.23 ? 469 LEU A O   1 
ATOM   3356 C  CB  . LEU A 1 481 ? 102.058 96.911  93.486  1.00 91.23 ? 469 LEU A CB  1 
ATOM   3357 C  CG  . LEU A 1 481 ? 101.195 96.513  94.684  1.00 91.23 ? 469 LEU A CG  1 
ATOM   3358 C  CD1 . LEU A 1 481 ? 99.767  96.248  94.238  1.00 91.23 ? 469 LEU A CD1 1 
ATOM   3359 C  CD2 . LEU A 1 481 ? 101.763 95.308  95.412  1.00 91.23 ? 469 LEU A CD2 1 
ATOM   3360 N  N   . TRP A 1 482 ? 103.899 98.873  91.870  1.00 93.62 ? 470 TRP A N   1 
ATOM   3361 C  CA  . TRP A 1 482 ? 104.445 99.269  90.588  1.00 93.62 ? 470 TRP A CA  1 
ATOM   3362 C  C   . TRP A 1 482 ? 105.954 99.301  90.611  1.00 93.62 ? 470 TRP A C   1 
ATOM   3363 O  O   . TRP A 1 482 ? 106.603 98.756  89.726  1.00 93.62 ? 470 TRP A O   1 
ATOM   3364 C  CB  . TRP A 1 482 ? 103.927 100.669 90.283  1.00 93.62 ? 470 TRP A CB  1 
ATOM   3365 C  CG  . TRP A 1 482 ? 104.223 101.213 88.933  1.00 93.62 ? 470 TRP A CG  1 
ATOM   3366 C  CD1 . TRP A 1 482 ? 105.303 101.958 88.568  1.00 93.62 ? 470 TRP A CD1 1 
ATOM   3367 C  CD2 . TRP A 1 482 ? 103.398 101.104 87.771  1.00 93.62 ? 470 TRP A CD2 1 
ATOM   3368 N  NE1 . TRP A 1 482 ? 105.213 102.300 87.243  1.00 93.62 ? 470 TRP A NE1 1 
ATOM   3369 C  CE2 . TRP A 1 482 ? 104.050 101.789 86.731  1.00 93.62 ? 470 TRP A CE2 1 
ATOM   3370 C  CE3 . TRP A 1 482 ? 102.175 100.484 87.506  1.00 93.62 ? 470 TRP A CE3 1 
ATOM   3371 C  CZ2 . TRP A 1 482 ? 103.524 101.868 85.447  1.00 93.62 ? 470 TRP A CZ2 1 
ATOM   3372 C  CZ3 . TRP A 1 482 ? 101.655 100.566 86.233  1.00 93.62 ? 470 TRP A CZ3 1 
ATOM   3373 C  CH2 . TRP A 1 482 ? 102.328 101.252 85.218  1.00 93.62 ? 470 TRP A CH2 1 
ATOM   3374 N  N   . VAL A 1 483 ? 106.521 99.910  91.640  1.00 96.59 ? 471 VAL A N   1 
ATOM   3375 C  CA  . VAL A 1 483 ? 107.970 99.977  91.757  1.00 96.59 ? 471 VAL A CA  1 
ATOM   3376 C  C   . VAL A 1 483 ? 108.573 98.599  91.978  1.00 96.59 ? 471 VAL A C   1 
ATOM   3377 O  O   . VAL A 1 483 ? 109.572 98.258  91.364  1.00 96.59 ? 471 VAL A O   1 
ATOM   3378 C  CB  . VAL A 1 483 ? 108.405 101.002 92.827  1.00 96.59 ? 471 VAL A CB  1 
ATOM   3379 C  CG1 . VAL A 1 483 ? 109.915 101.085 92.920  1.00 96.59 ? 471 VAL A CG1 1 
ATOM   3380 C  CG2 . VAL A 1 483 ? 107.849 102.371 92.479  1.00 96.59 ? 471 VAL A CG2 1 
ATOM   3381 N  N   . ALA A 1 484 ? 107.945 97.791  92.824  1.00 95.90 ? 472 ALA A N   1 
ATOM   3382 C  CA  . ALA A 1 484 ? 108.431 96.442  93.083  1.00 95.90 ? 472 ALA A CA  1 
ATOM   3383 C  C   . ALA A 1 484 ? 108.372 95.572  91.850  1.00 95.90 ? 472 ALA A C   1 
ATOM   3384 O  O   . ALA A 1 484 ? 109.293 94.806  91.591  1.00 95.90 ? 472 ALA A O   1 
ATOM   3385 C  CB  . ALA A 1 484 ? 107.650 95.801  94.209  1.00 95.90 ? 472 ALA A CB  1 
ATOM   3386 N  N   . PHE A 1 485 ? 107.293 95.683  91.085  1.00 96.67 ? 473 PHE A N   1 
ATOM   3387 C  CA  . PHE A 1 485 ? 107.159 94.875  89.899  1.00 96.67 ? 473 PHE A CA  1 
ATOM   3388 C  C   . PHE A 1 485 ? 108.275 95.229  88.962  1.00 96.67 ? 473 PHE A C   1 
ATOM   3389 O  O   . PHE A 1 485 ? 108.915 94.355  88.413  1.00 96.67 ? 473 PHE A O   1 
ATOM   3390 C  CB  . PHE A 1 485 ? 105.825 95.136  89.203  1.00 96.67 ? 473 PHE A CB  1 
ATOM   3391 C  CG  . PHE A 1 485 ? 105.761 94.613  87.797  1.00 96.67 ? 473 PHE A CG  1 
ATOM   3392 C  CD1 . PHE A 1 485 ? 105.634 93.258  87.555  1.00 96.67 ? 473 PHE A CD1 1 
ATOM   3393 C  CD2 . PHE A 1 485 ? 105.826 95.478  86.717  1.00 96.67 ? 473 PHE A CD2 1 
ATOM   3394 C  CE1 . PHE A 1 485 ? 105.580 92.774  86.264  1.00 96.67 ? 473 PHE A CE1 1 
ATOM   3395 C  CE2 . PHE A 1 485 ? 105.774 94.999  85.425  1.00 96.67 ? 473 PHE A CE2 1 
ATOM   3396 C  CZ  . PHE A 1 485 ? 105.649 93.645  85.198  1.00 96.67 ? 473 PHE A CZ  1 
ATOM   3397 N  N   . PHE A 1 486 ? 108.528 96.513  88.788  1.00 98.14 ? 474 PHE A N   1 
ATOM   3398 C  CA  . PHE A 1 486 ? 109.562 96.932  87.868  1.00 98.14 ? 474 PHE A CA  1 
ATOM   3399 C  C   . PHE A 1 486 ? 110.960 96.542  88.298  1.00 98.14 ? 474 PHE A C   1 
ATOM   3400 O  O   . PHE A 1 486 ? 111.762 96.146  87.476  1.00 98.14 ? 474 PHE A O   1 
ATOM   3401 C  CB  . PHE A 1 486 ? 109.430 98.400  87.488  1.00 98.14 ? 474 PHE A CB  1 
ATOM   3402 C  CG  . PHE A 1 486 ? 108.426 98.634  86.404  1.00 98.14 ? 474 PHE A CG  1 
ATOM   3403 C  CD1 . PHE A 1 486 ? 108.670 98.183  85.122  1.00 98.14 ? 474 PHE A CD1 1 
ATOM   3404 C  CD2 . PHE A 1 486 ? 107.232 99.271  86.667  1.00 98.14 ? 474 PHE A CD2 1 
ATOM   3405 C  CE1 . PHE A 1 486 ? 107.749 98.379  84.115  1.00 98.14 ? 474 PHE A CE1 1 
ATOM   3406 C  CE2 . PHE A 1 486 ? 106.305 99.467  85.667  1.00 98.14 ? 474 PHE A CE2 1 
ATOM   3407 C  CZ  . PHE A 1 486 ? 106.563 99.025  84.388  1.00 98.14 ? 474 PHE A CZ  1 
ATOM   3408 N  N   . GLU A 1 487 ? 111.253 96.630  89.586  1.00 97.94 ? 475 GLU A N   1 
ATOM   3409 C  CA  . GLU A 1 487 ? 112.556 96.208  90.057  1.00 97.94 ? 475 GLU A CA  1 
ATOM   3410 C  C   . GLU A 1 487 ? 112.754 94.737  89.788  1.00 97.94 ? 475 GLU A C   1 
ATOM   3411 O  O   . GLU A 1 487 ? 113.794 94.339  89.276  1.00 97.94 ? 475 GLU A O   1 
ATOM   3412 C  CB  . GLU A 1 487 ? 112.676 96.470  91.549  1.00 97.94 ? 475 GLU A CB  1 
ATOM   3413 C  CG  . GLU A 1 487 ? 112.732 97.940  91.900  1.00 97.94 ? 475 GLU A CG  1 
ATOM   3414 C  CD  . GLU A 1 487 ? 112.553 98.195  93.376  1.00 97.94 ? 475 GLU A CD  1 
ATOM   3415 O  OE1 . GLU A 1 487 ? 112.682 99.363  93.789  1.00 97.94 ? 475 GLU A OE1 1 
ATOM   3416 O  OE2 . GLU A 1 487 ? 112.282 97.230  94.118  1.00 97.94 ? 475 GLU A OE2 1 
ATOM   3417 N  N   . CYS A 1 488 ? 111.753 93.924  90.098  1.00 98.28 ? 476 CYS A N   1 
ATOM   3418 C  CA  . CYS A 1 488 ? 111.832 92.502  89.806  1.00 98.28 ? 476 CYS A CA  1 
ATOM   3419 C  C   . CYS A 1 488 ? 111.850 92.207  88.323  1.00 98.28 ? 476 CYS A C   1 
ATOM   3420 O  O   . CYS A 1 488 ? 112.595 91.347  87.877  1.00 98.28 ? 476 CYS A O   1 
ATOM   3421 C  CB  . CYS A 1 488 ? 110.686 91.764  90.478  1.00 98.28 ? 476 CYS A CB  1 
ATOM   3422 S  SG  . CYS A 1 488 ? 110.918 91.530  92.246  1.00 98.28 ? 476 CYS A SG  1 
ATOM   3423 N  N   . PHE A 1 489 ? 111.034 92.915  87.556  1.00 97.80 ? 477 PHE A N   1 
ATOM   3424 C  CA  . PHE A 1 489 ? 110.987 92.716  86.115  1.00 97.80 ? 477 PHE A CA  1 
ATOM   3425 C  C   . PHE A 1 489 ? 112.338 92.961  85.476  1.00 97.80 ? 477 PHE A C   1 
ATOM   3426 O  O   . PHE A 1 489 ? 112.822 92.137  84.711  1.00 97.80 ? 477 PHE A O   1 
ATOM   3427 C  CB  . PHE A 1 489 ? 109.943 93.637  85.481  1.00 97.80 ? 477 PHE A CB  1 
ATOM   3428 C  CG  . PHE A 1 489 ? 109.946 93.622  83.982  1.00 97.80 ? 477 PHE A CG  1 
ATOM   3429 C  CD1 . PHE A 1 489 ? 109.483 92.519  83.288  1.00 97.80 ? 477 PHE A CD1 1 
ATOM   3430 C  CD2 . PHE A 1 489 ? 110.400 94.716  83.268  1.00 97.80 ? 477 PHE A CD2 1 
ATOM   3431 C  CE1 . PHE A 1 489 ? 109.486 92.500  81.908  1.00 97.80 ? 477 PHE A CE1 1 
ATOM   3432 C  CE2 . PHE A 1 489 ? 110.406 94.704  81.888  1.00 97.80 ? 477 PHE A CE2 1 
ATOM   3433 C  CZ  . PHE A 1 489 ? 109.947 93.595  81.207  1.00 97.80 ? 477 PHE A CZ  1 
ATOM   3434 N  N   . VAL A 1 490 ? 112.944 94.103  85.760  1.00 97.91 ? 478 VAL A N   1 
ATOM   3435 C  CA  . VAL A 1 490 ? 114.204 94.423  85.115  1.00 97.91 ? 478 VAL A CA  1 
ATOM   3436 C  C   . VAL A 1 490 ? 115.317 93.458  85.471  1.00 97.91 ? 478 VAL A C   1 
ATOM   3437 O  O   . VAL A 1 490 ? 116.028 92.976  84.602  1.00 97.91 ? 478 VAL A O   1 
ATOM   3438 C  CB  . VAL A 1 490 ? 114.653 95.844  85.472  1.00 97.91 ? 478 VAL A CB  1 
ATOM   3439 C  CG1 . VAL A 1 490 ? 115.987 96.156  84.826  1.00 97.91 ? 478 VAL A CG1 1 
ATOM   3440 C  CG2 . VAL A 1 490 ? 113.608 96.840  85.027  1.00 97.91 ? 478 VAL A CG2 1 
ATOM   3441 N  N   . ILE A 1 491 ? 115.451 93.144  86.750  1.00 97.33 ? 479 ILE A N   1 
ATOM   3442 C  CA  . ILE A 1 491 ? 116.477 92.207  87.155  1.00 97.33 ? 479 ILE A CA  1 
ATOM   3443 C  C   . ILE A 1 491 ? 116.246 90.807  86.616  1.00 97.33 ? 479 ILE A C   1 
ATOM   3444 O  O   . ILE A 1 491 ? 117.148 90.199  86.066  1.00 97.33 ? 479 ILE A O   1 
ATOM   3445 C  CB  . ILE A 1 491 ? 116.603 92.165  88.680  1.00 97.33 ? 479 ILE A CB  1 
ATOM   3446 C  CG1 . ILE A 1 491 ? 117.426 93.354  89.152  1.00 97.33 ? 479 ILE A CG1 1 
ATOM   3447 C  CG2 . ILE A 1 491 ? 117.254 90.870  89.131  1.00 97.33 ? 479 ILE A CG2 1 
ATOM   3448 C  CD1 . ILE A 1 491 ? 118.853 93.318  88.661  1.00 97.33 ? 479 ILE A CD1 1 
ATOM   3449 N  N   . ALA A 1 492 ? 115.027 90.310  86.737  1.00 97.00 ? 480 ALA A N   1 
ATOM   3450 C  CA  . ALA A 1 492 ? 114.727 88.978  86.257  1.00 97.00 ? 480 ALA A CA  1 
ATOM   3451 C  C   . ALA A 1 492 ? 114.759 88.800  84.758  1.00 97.00 ? 480 ALA A C   1 
ATOM   3452 O  O   . ALA A 1 492 ? 115.289 87.807  84.266  1.00 97.00 ? 480 ALA A O   1 
ATOM   3453 C  CB  . ALA A 1 492 ? 113.391 88.528  86.800  1.00 97.00 ? 480 ALA A CB  1 
ATOM   3454 N  N   . TRP A 1 493 ? 114.202 89.749  84.018  1.00 96.35 ? 481 TRP A N   1 
ATOM   3455 C  CA  . TRP A 1 493 ? 114.089 89.568  82.573  1.00 96.35 ? 481 TRP A CA  1 
ATOM   3456 C  C   . TRP A 1 493 ? 115.013 90.361  81.660  1.00 96.35 ? 481 TRP A C   1 
ATOM   3457 O  O   . TRP A 1 493 ? 115.261 89.946  80.535  1.00 96.35 ? 481 TRP A O   1 
ATOM   3458 C  CB  . TRP A 1 493 ? 112.640 89.797  82.159  1.00 96.35 ? 481 TRP A CB  1 
ATOM   3459 C  CG  . TRP A 1 493 ? 111.677 88.940  82.914  1.00 96.35 ? 481 TRP A CG  1 
ATOM   3460 C  CD1 . TRP A 1 493 ? 110.881 89.319  83.954  1.00 96.35 ? 481 TRP A CD1 1 
ATOM   3461 C  CD2 . TRP A 1 493 ? 111.418 87.551  82.697  1.00 96.35 ? 481 TRP A CD2 1 
ATOM   3462 N  NE1 . TRP A 1 493 ? 110.137 88.253  84.393  1.00 96.35 ? 481 TRP A NE1 1 
ATOM   3463 C  CE2 . TRP A 1 493 ? 110.449 87.155  83.637  1.00 96.35 ? 481 TRP A CE2 1 
ATOM   3464 C  CE3 . TRP A 1 493 ? 111.909 86.603  81.795  1.00 96.35 ? 481 TRP A CE3 1 
ATOM   3465 C  CZ2 . TRP A 1 493 ? 109.961 85.853  83.700  1.00 96.35 ? 481 TRP A CZ2 1 
ATOM   3466 C  CZ3 . TRP A 1 493 ? 111.425 85.313  81.860  1.00 96.35 ? 481 TRP A CZ3 1 
ATOM   3467 C  CH2 . TRP A 1 493 ? 110.461 84.949  82.806  1.00 96.35 ? 481 TRP A CH2 1 
ATOM   3468 N  N   . ILE A 1 494 ? 115.506 91.498  82.119  1.00 95.25 ? 482 ILE A N   1 
ATOM   3469 C  CA  . ILE A 1 494 ? 116.422 92.284  81.311  1.00 95.25 ? 482 ILE A CA  1 
ATOM   3470 C  C   . ILE A 1 494 ? 117.864 92.018  81.713  1.00 95.25 ? 482 ILE A C   1 
ATOM   3471 O  O   . ILE A 1 494 ? 118.650 91.521  80.910  1.00 95.25 ? 482 ILE A O   1 
ATOM   3472 C  CB  . ILE A 1 494 ? 116.093 93.778  81.391  1.00 95.25 ? 482 ILE A CB  1 
ATOM   3473 C  CG1 . ILE A 1 494 ? 114.632 93.997  81.010  1.00 95.25 ? 482 ILE A CG1 1 
ATOM   3474 C  CG2 . ILE A 1 494 ? 117.019 94.575  80.487  1.00 95.25 ? 482 ILE A CG2 1 
ATOM   3475 C  CD1 . ILE A 1 494 ? 114.142 95.394  81.278  1.00 95.25 ? 482 ILE A CD1 1 
ATOM   3476 N  N   . TYR A 1 495 ? 118.217 92.331  82.954  1.00 94.15 ? 483 TYR A N   1 
ATOM   3477 C  CA  . TYR A 1 495 ? 119.563 92.056  83.434  1.00 94.15 ? 483 TYR A CA  1 
ATOM   3478 C  C   . TYR A 1 495 ? 119.813 90.566  83.435  1.00 94.15 ? 483 TYR A C   1 
ATOM   3479 O  O   . TYR A 1 495 ? 120.889 90.113  83.057  1.00 94.15 ? 483 TYR A O   1 
ATOM   3480 C  CB  . TYR A 1 495 ? 119.756 92.616  84.842  1.00 94.15 ? 483 TYR A CB  1 
ATOM   3481 C  CG  . TYR A 1 495 ? 121.180 92.527  85.329  1.00 94.15 ? 483 TYR A CG  1 
ATOM   3482 C  CD1 . TYR A 1 495 ? 122.145 93.402  84.859  1.00 94.15 ? 483 TYR A CD1 1 
ATOM   3483 C  CD2 . TYR A 1 495 ? 121.561 91.565  86.252  1.00 94.15 ? 483 TYR A CD2 1 
ATOM   3484 C  CE1 . TYR A 1 495 ? 123.450 93.324  85.296  1.00 94.15 ? 483 TYR A CE1 1 
ATOM   3485 C  CE2 . TYR A 1 495 ? 122.865 91.480  86.692  1.00 94.15 ? 483 TYR A CE2 1 
ATOM   3486 C  CZ  . TYR A 1 495 ? 123.804 92.363  86.212  1.00 94.15 ? 483 TYR A CZ  1 
ATOM   3487 O  OH  . TYR A 1 495 ? 125.102 92.282  86.648  1.00 94.15 ? 483 TYR A OH  1 
ATOM   3488 N  N   . GLY A 1 496 ? 118.819 89.797  83.851  1.00 93.94 ? 484 GLY A N   1 
ATOM   3489 C  CA  . GLY A 1 496 ? 118.963 88.358  83.916  1.00 93.94 ? 484 GLY A CA  1 
ATOM   3490 C  C   . GLY A 1 496 ? 119.206 87.943  85.341  1.00 93.94 ? 484 GLY A C   1 
ATOM   3491 O  O   . GLY A 1 496 ? 120.250 88.267  85.895  1.00 93.94 ? 484 GLY A O   1 
ATOM   3492 N  N   . GLY A 1 497 ? 118.267 87.210  85.930  1.00 93.39 ? 485 GLY A N   1 
ATOM   3493 C  CA  . GLY A 1 497 ? 118.388 86.776  87.312  1.00 93.39 ? 485 GLY A CA  1 
ATOM   3494 C  C   . GLY A 1 497 ? 119.567 85.867  87.521  1.00 93.39 ? 485 GLY A C   1 
ATOM   3495 O  O   . GLY A 1 497 ? 120.228 85.954  88.543  1.00 93.39 ? 485 GLY A O   1 
ATOM   3496 N  N   . ASP A 1 498 ? 119.823 84.976  86.573  1.00 93.48 ? 486 ASP A N   1 
ATOM   3497 C  CA  . ASP A 1 498 ? 120.979 84.091  86.653  1.00 93.48 ? 486 ASP A CA  1 
ATOM   3498 C  C   . ASP A 1 498 ? 122.279 84.875  86.613  1.00 93.48 ? 486 ASP A C   1 
ATOM   3499 O  O   . ASP A 1 498 ? 123.232 84.531  87.299  1.00 93.48 ? 486 ASP A O   1 
ATOM   3500 C  CB  . ASP A 1 498 ? 120.955 83.089  85.503  1.00 93.48 ? 486 ASP A CB  1 
ATOM   3501 C  CG  . ASP A 1 498 ? 121.851 81.896  85.752  1.00 93.48 ? 486 ASP A CG  1 
ATOM   3502 O  OD1 . ASP A 1 498 ? 122.054 81.541  86.931  1.00 93.48 ? 486 ASP A OD1 1 
ATOM   3503 O  OD2 . ASP A 1 498 ? 122.341 81.306  84.769  1.00 93.48 ? 486 ASP A OD2 1 
ATOM   3504 N  N   . ASN A 1 499 ? 122.338 85.911  85.785  1.00 91.74 ? 487 ASN A N   1 
ATOM   3505 C  CA  . ASN A 1 499 ? 123.531 86.747  85.717  1.00 91.74 ? 487 ASN A CA  1 
ATOM   3506 C  C   . ASN A 1 499 ? 123.742 87.418  87.054  1.00 91.74 ? 487 ASN A C   1 
ATOM   3507 O  O   . ASN A 1 499 ? 124.870 87.521  87.530  1.00 91.74 ? 487 ASN A O   1 
ATOM   3508 C  CB  . ASN A 1 499 ? 123.395 87.801  84.623  1.00 91.74 ? 487 ASN A CB  1 
ATOM   3509 C  CG  . ASN A 1 499 ? 123.070 87.203  83.270  1.00 91.74 ? 487 ASN A CG  1 
ATOM   3510 O  OD1 . ASN A 1 499 ? 123.019 85.984  83.109  1.00 91.74 ? 487 ASN A OD1 1 
ATOM   3511 N  ND2 . ASN A 1 499 ? 122.850 88.063  82.284  1.00 91.74 ? 487 ASN A ND2 1 
ATOM   3512 N  N   . LEU A 1 500 ? 122.661 87.884  87.669  1.00 94.21 ? 488 LEU A N   1 
ATOM   3513 C  CA  . LEU A 1 500 ? 122.775 88.466  88.994  1.00 94.21 ? 488 LEU A CA  1 
ATOM   3514 C  C   . LEU A 1 500 ? 123.234 87.395  89.958  1.00 94.21 ? 488 LEU A C   1 
ATOM   3515 O  O   . LEU A 1 500 ? 124.027 87.671  90.824  1.00 94.21 ? 488 LEU A O   1 
ATOM   3516 C  CB  . LEU A 1 500 ? 121.474 89.107  89.467  1.00 94.21 ? 488 LEU A CB  1 
ATOM   3517 C  CG  . LEU A 1 500 ? 121.638 89.972  90.716  1.00 94.21 ? 488 LEU A CG  1 
ATOM   3518 C  CD1 . LEU A 1 500 ? 122.640 91.093  90.490  1.00 94.21 ? 488 LEU A CD1 1 
ATOM   3519 C  CD2 . LEU A 1 500 ? 120.309 90.525  91.184  1.00 94.21 ? 488 LEU A CD2 1 
ATOM   3520 N  N   . TYR A 1 501 ? 122.749 86.170  89.800  1.00 95.09 ? 489 TYR A N   1 
ATOM   3521 C  CA  . TYR A 1 501 ? 123.152 85.066  90.668  1.00 95.09 ? 489 TYR A CA  1 
ATOM   3522 C  C   . TYR A 1 501 ? 124.634 84.783  90.570  1.00 95.09 ? 489 TYR A C   1 
ATOM   3523 O  O   . TYR A 1 501 ? 125.243 84.413  91.555  1.00 95.09 ? 489 TYR A O   1 
ATOM   3524 C  CB  . TYR A 1 501 ? 122.377 83.797  90.349  1.00 95.09 ? 489 TYR A CB  1 
ATOM   3525 C  CG  . TYR A 1 501 ? 121.245 83.500  91.287  1.00 95.09 ? 489 TYR A CG  1 
ATOM   3526 C  CD1 . TYR A 1 501 ? 120.435 84.513  91.776  1.00 95.09 ? 489 TYR A CD1 1 
ATOM   3527 C  CD2 . TYR A 1 501 ? 120.975 82.200  91.671  1.00 95.09 ? 489 TYR A CD2 1 
ATOM   3528 C  CE1 . TYR A 1 501 ? 119.391 84.236  92.633  1.00 95.09 ? 489 TYR A CE1 1 
ATOM   3529 C  CE2 . TYR A 1 501 ? 119.934 81.914  92.523  1.00 95.09 ? 489 TYR A CE2 1 
ATOM   3530 C  CZ  . TYR A 1 501 ? 119.148 82.935  93.001  1.00 95.09 ? 489 TYR A CZ  1 
ATOM   3531 O  OH  . TYR A 1 501 ? 118.114 82.643  93.850  1.00 95.09 ? 489 TYR A OH  1 
ATOM   3532 N  N   . ASP A 1 502 ? 125.245 85.006  89.416  1.00 93.29 ? 490 ASP A N   1 
ATOM   3533 C  CA  . ASP A 1 502 ? 126.694 84.850  89.316  1.00 93.29 ? 490 ASP A CA  1 
ATOM   3534 C  C   . ASP A 1 502 ? 127.333 85.882  90.217  1.00 93.29 ? 490 ASP A C   1 
ATOM   3535 O  O   . ASP A 1 502 ? 128.242 85.567  90.981  1.00 93.29 ? 490 ASP A O   1 
ATOM   3536 C  CB  . ASP A 1 502 ? 127.168 85.057  87.881  1.00 93.29 ? 490 ASP A CB  1 
ATOM   3537 C  CG  . ASP A 1 502 ? 126.599 84.032  86.925  1.00 93.29 ? 490 ASP A CG  1 
ATOM   3538 O  OD1 . ASP A 1 502 ? 126.419 82.871  87.340  1.00 93.29 ? 490 ASP A OD1 1 
ATOM   3539 O  OD2 . ASP A 1 502 ? 126.344 84.382  85.754  1.00 93.29 ? 490 ASP A OD2 1 
ATOM   3540 N  N   . GLY A 1 503 ? 126.867 87.122  90.126  1.00 91.56 ? 491 GLY A N   1 
ATOM   3541 C  CA  . GLY A 1 503 ? 127.382 88.182  90.976  1.00 91.56 ? 491 GLY A CA  1 
ATOM   3542 C  C   . GLY A 1 503 ? 127.121 87.995  92.453  1.00 91.56 ? 491 GLY A C   1 
ATOM   3543 O  O   . GLY A 1 503 ? 127.991 88.268  93.265  1.00 91.56 ? 491 GLY A O   1 
ATOM   3544 N  N   . ILE A 1 504 ? 125.930 87.533  92.812  1.00 95.17 ? 492 ILE A N   1 
ATOM   3545 C  CA  . ILE A 1 504 ? 125.616 87.269  94.210  1.00 95.17 ? 492 ILE A CA  1 
ATOM   3546 C  C   . ILE A 1 504 ? 126.522 86.171  94.731  1.00 95.17 ? 492 ILE A C   1 
ATOM   3547 O  O   . ILE A 1 504 ? 127.027 86.251  95.837  1.00 95.17 ? 492 ILE A O   1 
ATOM   3548 C  CB  . ILE A 1 504 ? 124.144 86.861  94.401  1.00 95.17 ? 492 ILE A CB  1 
ATOM   3549 C  CG1 . ILE A 1 504 ? 123.207 87.950  93.891  1.00 95.17 ? 492 ILE A CG1 1 
ATOM   3550 C  CG2 . ILE A 1 504 ? 123.840 86.601  95.861  1.00 95.17 ? 492 ILE A CG2 1 
ATOM   3551 C  CD1 . ILE A 1 504 ? 121.748 87.561  93.949  1.00 95.17 ? 492 ILE A CD1 1 
ATOM   3552 N  N   . GLU A 1 505 ? 126.755 85.153  93.919  1.00 95.60 ? 493 GLU A N   1 
ATOM   3553 C  CA  . GLU A 1 505 ? 127.622 84.066  94.328  1.00 95.60 ? 493 GLU A CA  1 
ATOM   3554 C  C   . GLU A 1 505 ? 129.024 84.572  94.579  1.00 95.60 ? 493 GLU A C   1 
ATOM   3555 O  O   . GLU A 1 505 ? 129.667 84.161  95.532  1.00 95.60 ? 493 GLU A O   1 
ATOM   3556 C  CB  . GLU A 1 505 ? 127.657 82.984  93.255  1.00 95.60 ? 493 GLU A CB  1 
ATOM   3557 C  CG  . GLU A 1 505 ? 128.608 81.835  93.533  1.00 95.60 ? 493 GLU A CG  1 
ATOM   3558 C  CD  . GLU A 1 505 ? 128.630 80.829  92.404  1.00 95.60 ? 493 GLU A CD  1 
ATOM   3559 O  OE1 . GLU A 1 505 ? 129.451 79.890  92.459  1.00 95.60 ? 493 GLU A OE1 1 
ATOM   3560 O  OE2 . GLU A 1 505 ? 127.827 80.982  91.460  1.00 95.60 ? 493 GLU A OE2 1 
ATOM   3561 N  N   . ASP A 1 506 ? 129.520 85.459  93.729  1.00 92.91 ? 494 ASP A N   1 
ATOM   3562 C  CA  . ASP A 1 506 ? 130.831 86.014  93.995  1.00 92.91 ? 494 ASP A CA  1 
ATOM   3563 C  C   . ASP A 1 506 ? 130.829 86.813  95.285  1.00 92.91 ? 494 ASP A C   1 
ATOM   3564 O  O   . ASP A 1 506 ? 131.638 86.554  96.161  1.00 92.91 ? 494 ASP A O   1 
ATOM   3565 C  CB  . ASP A 1 506 ? 131.233 86.932  92.841  1.00 92.91 ? 494 ASP A CB  1 
ATOM   3566 C  CG  . ASP A 1 506 ? 132.696 87.313  92.876  1.00 92.91 ? 494 ASP A CG  1 
ATOM   3567 O  OD1 . ASP A 1 506 ? 133.510 86.513  93.381  1.00 92.91 ? 494 ASP A OD1 1 
ATOM   3568 O  OD2 . ASP A 1 506 ? 133.034 88.409  92.381  1.00 92.91 ? 494 ASP A OD2 1 
ATOM   3569 N  N   . MET A 1 507 ? 129.860 87.703  95.453  1.00 94.06 ? 495 MET A N   1 
ATOM   3570 C  CA  . MET A 1 507 ? 129.803 88.552  96.635  1.00 94.06 ? 495 MET A CA  1 
ATOM   3571 C  C   . MET A 1 507 ? 129.561 87.824  97.930  1.00 94.06 ? 495 MET A C   1 
ATOM   3572 O  O   . MET A 1 507 ? 130.194 88.109  98.937  1.00 94.06 ? 495 MET A O   1 
ATOM   3573 C  CB  . MET A 1 507 ? 128.675 89.557  96.478  1.00 94.06 ? 495 MET A CB  1 
ATOM   3574 C  CG  . MET A 1 507 ? 128.888 90.592  95.403  1.00 94.06 ? 495 MET A CG  1 
ATOM   3575 S  SD  . MET A 1 507 ? 127.611 91.850  95.490  1.00 94.06 ? 495 MET A SD  1 
ATOM   3576 C  CE  . MET A 1 507 ? 126.209 90.927  94.882  1.00 94.06 ? 495 MET A CE  1 
ATOM   3577 N  N   . ILE A 1 508 ? 128.588 86.921  97.942  1.00 95.42 ? 496 ILE A N   1 
ATOM   3578 C  CA  . ILE A 1 508 ? 128.199 86.229  99.175  1.00 95.42 ? 496 ILE A CA  1 
ATOM   3579 C  C   . ILE A 1 508 ? 129.089 85.023  99.454  1.00 95.42 ? 496 ILE A C   1 
ATOM   3580 O  O   . ILE A 1 508 ? 129.287 84.639  100.607 1.00 95.42 ? 496 ILE A O   1 
ATOM   3581 C  CB  . ILE A 1 508 ? 126.690 85.859  99.104  1.00 95.42 ? 496 ILE A CB  1 
ATOM   3582 C  CG1 . ILE A 1 508 ? 125.830 86.930  99.772  1.00 95.42 ? 496 ILE A CG1 1 
ATOM   3583 C  CG2 . ILE A 1 508 ? 126.386 84.501  99.697  1.00 95.42 ? 496 ILE A CG2 1 
ATOM   3584 C  CD1 . ILE A 1 508 ? 125.688 88.193  98.960  1.00 95.42 ? 496 ILE A CD1 1 
ATOM   3585 N  N   . GLY A 1 509 ? 129.632 84.418  98.408  1.00 94.42 ? 497 GLY A N   1 
ATOM   3586 C  CA  . GLY A 1 509 ? 130.490 83.261  98.584  1.00 94.42 ? 497 GLY A CA  1 
ATOM   3587 C  C   . GLY A 1 509 ? 129.825 81.989  98.113  1.00 94.42 ? 497 GLY A C   1 
ATOM   3588 O  O   . GLY A 1 509 ? 130.484 81.102  97.576  1.00 94.42 ? 497 GLY A O   1 
ATOM   3589 N  N   . TYR A 1 510 ? 128.515 81.892  98.308  1.00 96.07 ? 498 TYR A N   1 
ATOM   3590 C  CA  . TYR A 1 510 ? 127.779 80.715  97.868  1.00 96.07 ? 498 TYR A CA  1 
ATOM   3591 C  C   . TYR A 1 510 ? 126.644 81.093  96.931  1.00 96.07 ? 498 TYR A C   1 
ATOM   3592 O  O   . TYR A 1 510 ? 126.003 82.124  97.118  1.00 96.07 ? 498 TYR A O   1 
ATOM   3593 C  CB  . TYR A 1 510 ? 127.258 79.901  99.061  1.00 96.07 ? 498 TYR A CB  1 
ATOM   3594 C  CG  . TYR A 1 510 ? 126.319 80.618  100.011 1.00 96.07 ? 498 TYR A CG  1 
ATOM   3595 C  CD1 . TYR A 1 510 ? 124.950 80.655  99.776  1.00 96.07 ? 498 TYR A CD1 1 
ATOM   3596 C  CD2 . TYR A 1 510 ? 126.797 81.222  101.166 1.00 96.07 ? 498 TYR A CD2 1 
ATOM   3597 C  CE1 . TYR A 1 510 ? 124.091 81.299  100.643 1.00 96.07 ? 498 TYR A CE1 1 
ATOM   3598 C  CE2 . TYR A 1 510 ? 125.944 81.864  102.042 1.00 96.07 ? 498 TYR A CE2 1 
ATOM   3599 C  CZ  . TYR A 1 510 ? 124.594 81.901  101.775 1.00 96.07 ? 498 TYR A CZ  1 
ATOM   3600 O  OH  . TYR A 1 510 ? 123.742 82.542  102.646 1.00 96.07 ? 498 TYR A OH  1 
ATOM   3601 N  N   . ARG A 1 511 ? 126.409 80.286  95.904  1.00 94.77 ? 499 ARG A N   1 
ATOM   3602 C  CA  . ARG A 1 511 ? 125.286 80.555  95.023  1.00 94.77 ? 499 ARG A CA  1 
ATOM   3603 C  C   . ARG A 1 511 ? 124.011 80.362  95.817  1.00 94.77 ? 499 ARG A C   1 
ATOM   3604 O  O   . ARG A 1 511 ? 123.848 79.353  96.498  1.00 94.77 ? 499 ARG A O   1 
ATOM   3605 C  CB  . ARG A 1 511 ? 125.326 79.620  93.816  1.00 94.77 ? 499 ARG A CB  1 
ATOM   3606 C  CG  . ARG A 1 511 ? 124.092 79.654  92.933  1.00 94.77 ? 499 ARG A CG  1 
ATOM   3607 C  CD  . ARG A 1 511 ? 124.372 79.005  91.591  1.00 94.77 ? 499 ARG A CD  1 
ATOM   3608 N  NE  . ARG A 1 511 ? 124.870 79.971  90.619  1.00 94.77 ? 499 ARG A NE  1 
ATOM   3609 C  CZ  . ARG A 1 511 ? 124.119 80.530  89.677  1.00 94.77 ? 499 ARG A CZ  1 
ATOM   3610 N  NH1 . ARG A 1 511 ? 122.838 80.207  89.569  1.00 94.77 ? 499 ARG A NH1 1 
ATOM   3611 N  NH2 . ARG A 1 511 ? 124.649 81.402  88.835  1.00 94.77 ? 499 ARG A NH2 1 
ATOM   3612 N  N   . PRO A 1 512 ? 123.089 81.325  95.725  1.00 94.25 ? 500 PRO A N   1 
ATOM   3613 C  CA  . PRO A 1 512 ? 121.835 81.238  96.475  1.00 94.25 ? 500 PRO A CA  1 
ATOM   3614 C  C   . PRO A 1 512 ? 120.897 80.185  95.922  1.00 94.25 ? 500 PRO A C   1 
ATOM   3615 O  O   . PRO A 1 512 ? 121.022 79.790  94.765  1.00 94.25 ? 500 PRO A O   1 
ATOM   3616 C  CB  . PRO A 1 512 ? 121.218 82.627  96.301  1.00 94.25 ? 500 PRO A CB  1 
ATOM   3617 C  CG  . PRO A 1 512 ? 122.326 83.502  95.848  1.00 94.25 ? 500 PRO A CG  1 
ATOM   3618 C  CD  . PRO A 1 512 ? 123.243 82.627  95.059  1.00 94.25 ? 500 PRO A CD  1 
ATOM   3619 N  N   . GLY A 1 513 ? 119.973 79.713  96.746  1.00 91.61 ? 501 GLY A N   1 
ATOM   3620 C  CA  . GLY A 1 513 ? 118.997 78.746  96.286  1.00 91.61 ? 501 GLY A CA  1 
ATOM   3621 C  C   . GLY A 1 513 ? 118.014 79.260  95.227  1.00 91.61 ? 501 GLY A C   1 
ATOM   3622 O  O   . GLY A 1 513 ? 117.951 80.459  95.016  1.00 91.61 ? 501 GLY A O   1 
ATOM   3623 N  N   . PRO A 1 514 ? 117.202 78.379  94.583  1.00 94.50 ? 502 PRO A N   1 
ATOM   3624 C  CA  . PRO A 1 514 ? 116.350 78.863  93.491  1.00 94.50 ? 502 PRO A CA  1 
ATOM   3625 C  C   . PRO A 1 514 ? 115.257 79.852  93.911  1.00 94.50 ? 502 PRO A C   1 
ATOM   3626 O  O   . PRO A 1 514 ? 114.648 80.452  93.036  1.00 94.50 ? 502 PRO A O   1 
ATOM   3627 C  CB  . PRO A 1 514 ? 115.741 77.573  92.934  1.00 94.50 ? 502 PRO A CB  1 
ATOM   3628 C  CG  . PRO A 1 514 ? 115.766 76.617  94.074  1.00 94.50 ? 502 PRO A CG  1 
ATOM   3629 C  CD  . PRO A 1 514 ? 117.004 76.946  94.856  1.00 94.50 ? 502 PRO A CD  1 
ATOM   3630 N  N   . TRP A 1 515 ? 115.001 80.021  95.203  1.00 95.89 ? 503 TRP A N   1 
ATOM   3631 C  CA  . TRP A 1 515 ? 113.901 80.871  95.667  1.00 95.89 ? 503 TRP A CA  1 
ATOM   3632 C  C   . TRP A 1 515 ? 113.971 82.335  95.256  1.00 95.89 ? 503 TRP A C   1 
ATOM   3633 O  O   . TRP A 1 515 ? 112.970 82.893  94.819  1.00 95.89 ? 503 TRP A O   1 
ATOM   3634 C  CB  . TRP A 1 515 ? 113.835 80.761  97.194  1.00 95.89 ? 503 TRP A CB  1 
ATOM   3635 C  CG  . TRP A 1 515 ? 112.893 81.684  97.918  1.00 95.89 ? 503 TRP A CG  1 
ATOM   3636 C  CD1 . TRP A 1 515 ? 111.659 82.103  97.511  1.00 95.89 ? 503 TRP A CD1 1 
ATOM   3637 C  CD2 . TRP A 1 515 ? 113.102 82.258  99.211  1.00 95.89 ? 503 TRP A CD2 1 
ATOM   3638 N  NE1 . TRP A 1 515 ? 111.104 82.926  98.457  1.00 95.89 ? 503 TRP A NE1 1 
ATOM   3639 C  CE2 . TRP A 1 515 ? 111.970 83.034  99.514  1.00 95.89 ? 503 TRP A CE2 1 
ATOM   3640 C  CE3 . TRP A 1 515 ? 114.145 82.198  100.139 1.00 95.89 ? 503 TRP A CE3 1 
ATOM   3641 C  CZ2 . TRP A 1 515 ? 111.850 83.743  100.704 1.00 95.89 ? 503 TRP A CZ2 1 
ATOM   3642 C  CZ3 . TRP A 1 515 ? 114.023 82.901  101.318 1.00 95.89 ? 503 TRP A CZ3 1 
ATOM   3643 C  CH2 . TRP A 1 515 ? 112.885 83.664  101.590 1.00 95.89 ? 503 TRP A CH2 1 
ATOM   3644 N  N   . MET A 1 516 ? 115.134 82.960  95.357  1.00 95.70 ? 504 MET A N   1 
ATOM   3645 C  CA  . MET A 1 516 ? 115.226 84.384  95.045  1.00 95.70 ? 504 MET A CA  1 
ATOM   3646 C  C   . MET A 1 516 ? 114.908 84.690  93.595  1.00 95.70 ? 504 MET A C   1 
ATOM   3647 O  O   . MET A 1 516 ? 114.165 85.610  93.317  1.00 95.70 ? 504 MET A O   1 
ATOM   3648 C  CB  . MET A 1 516 ? 116.605 84.928  95.404  1.00 95.70 ? 504 MET A CB  1 
ATOM   3649 C  CG  . MET A 1 516 ? 116.879 84.963  96.890  1.00 95.70 ? 504 MET A CG  1 
ATOM   3650 S  SD  . MET A 1 516 ? 115.937 86.292  97.642  1.00 95.70 ? 504 MET A SD  1 
ATOM   3651 C  CE  . MET A 1 516 ? 115.332 85.501  99.122  1.00 95.70 ? 504 MET A CE  1 
ATOM   3652 N  N   . LYS A 1 517 ? 115.427 83.894  92.671  1.00 95.74 ? 505 LYS A N   1 
ATOM   3653 C  CA  . LYS A 1 517 ? 115.209 84.164  91.256  1.00 95.74 ? 505 LYS A CA  1 
ATOM   3654 C  C   . LYS A 1 517 ? 113.786 83.867  90.826  1.00 95.74 ? 505 LYS A C   1 
ATOM   3655 O  O   . LYS A 1 517 ? 113.223 84.601  90.029  1.00 95.74 ? 505 LYS A O   1 
ATOM   3656 C  CB  . LYS A 1 517 ? 116.208 83.412  90.371  1.00 95.74 ? 505 LYS A CB  1 
ATOM   3657 C  CG  . LYS A 1 517 ? 116.338 81.930  90.659  1.00 95.74 ? 505 LYS A CG  1 
ATOM   3658 C  CD  . LYS A 1 517 ? 117.070 81.222  89.535  1.00 95.74 ? 505 LYS A CD  1 
ATOM   3659 C  CE  . LYS A 1 517 ? 118.301 82.001  89.111  1.00 95.74 ? 505 LYS A CE  1 
ATOM   3660 N  NZ  . LYS A 1 517 ? 119.114 81.253  88.115  1.00 95.74 ? 505 LYS A NZ  1 
ATOM   3661 N  N   . TYR A 1 518 ? 113.200 82.798  91.349  1.00 97.21 ? 506 TYR A N   1 
ATOM   3662 C  CA  . TYR A 1 518 ? 111.823 82.462  91.019  1.00 97.21 ? 506 TYR A CA  1 
ATOM   3663 C  C   . TYR A 1 518 ? 110.884 83.537  91.497  1.00 97.21 ? 506 TYR A C   1 
ATOM   3664 O  O   . TYR A 1 518 ? 109.928 83.872  90.817  1.00 97.21 ? 506 TYR A O   1 
ATOM   3665 C  CB  . TYR A 1 518 ? 111.421 81.117  91.613  1.00 97.21 ? 506 TYR A CB  1 
ATOM   3666 C  CG  . TYR A 1 518 ? 112.108 79.933  90.974  1.00 97.21 ? 506 TYR A CG  1 
ATOM   3667 C  CD1 . TYR A 1 518 ? 112.759 80.055  89.754  1.00 97.21 ? 506 TYR A CD1 1 
ATOM   3668 C  CD2 . TYR A 1 518 ? 112.094 78.688  91.586  1.00 97.21 ? 506 TYR A CD2 1 
ATOM   3669 C  CE1 . TYR A 1 518 ? 113.388 78.974  89.169  1.00 97.21 ? 506 TYR A CE1 1 
ATOM   3670 C  CE2 . TYR A 1 518 ? 112.716 77.600  91.006  1.00 97.21 ? 506 TYR A CE2 1 
ATOM   3671 C  CZ  . TYR A 1 518 ? 113.362 77.749  89.799  1.00 97.21 ? 506 TYR A CZ  1 
ATOM   3672 O  OH  . TYR A 1 518 ? 113.983 76.667  89.218  1.00 97.21 ? 506 TYR A OH  1 
ATOM   3673 N  N   . SER A 1 519 ? 111.151 84.092  92.666  1.00 97.58 ? 507 SER A N   1 
ATOM   3674 C  CA  . SER A 1 519 ? 110.329 85.171  93.172  1.00 97.58 ? 507 SER A CA  1 
ATOM   3675 C  C   . SER A 1 519 ? 110.438 86.408  92.298  1.00 97.58 ? 507 SER A C   1 
ATOM   3676 O  O   . SER A 1 519 ? 109.437 87.011  91.954  1.00 97.58 ? 507 SER A O   1 
ATOM   3677 C  CB  . SER A 1 519 ? 110.720 85.497  94.592  1.00 97.58 ? 507 SER A CB  1 
ATOM   3678 O  OG  . SER A 1 519 ? 110.454 84.404  95.447  1.00 97.58 ? 507 SER A OG  1 
ATOM   3679 N  N   . TRP A 1 520 ? 111.650 86.764  91.903  1.00 97.70 ? 508 TRP A N   1 
ATOM   3680 C  CA  . TRP A 1 520 ? 111.842 87.932  91.069  1.00 97.70 ? 508 TRP A CA  1 
ATOM   3681 C  C   . TRP A 1 520 ? 111.213 87.727  89.715  1.00 97.70 ? 508 TRP A C   1 
ATOM   3682 O  O   . TRP A 1 520 ? 110.562 88.616  89.200  1.00 97.70 ? 508 TRP A O   1 
ATOM   3683 C  CB  . TRP A 1 520 ? 113.324 88.259  90.895  1.00 97.70 ? 508 TRP A CB  1 
ATOM   3684 C  CG  . TRP A 1 520 ? 114.069 88.507  92.161  1.00 97.70 ? 508 TRP A CG  1 
ATOM   3685 C  CD1 . TRP A 1 520 ? 113.568 88.997  93.327  1.00 97.70 ? 508 TRP A CD1 1 
ATOM   3686 C  CD2 . TRP A 1 520 ? 115.466 88.288  92.384  1.00 97.70 ? 508 TRP A CD2 1 
ATOM   3687 N  NE1 . TRP A 1 520 ? 114.562 89.086  94.267  1.00 97.70 ? 508 TRP A NE1 1 
ATOM   3688 C  CE2 . TRP A 1 520 ? 115.738 88.656  93.713  1.00 97.70 ? 508 TRP A CE2 1 
ATOM   3689 C  CE3 . TRP A 1 520 ? 116.511 87.809  91.590  1.00 97.70 ? 508 TRP A CE3 1 
ATOM   3690 C  CZ2 . TRP A 1 520 ? 117.010 88.565  94.266  1.00 97.70 ? 508 TRP A CZ2 1 
ATOM   3691 C  CZ3 . TRP A 1 520 ? 117.771 87.718  92.140  1.00 97.70 ? 508 TRP A CZ3 1 
ATOM   3692 C  CH2 . TRP A 1 520 ? 118.011 88.096  93.464  1.00 97.70 ? 508 TRP A CH2 1 
ATOM   3693 N  N   . ALA A 1 521 ? 111.475 86.586  89.095  1.00 97.97 ? 509 ALA A N   1 
ATOM   3694 C  CA  . ALA A 1 521 ? 110.910 86.290  87.780  1.00 97.97 ? 509 ALA A CA  1 
ATOM   3695 C  C   . ALA A 1 521 ? 109.416 86.088  87.710  1.00 97.97 ? 509 ALA A C   1 
ATOM   3696 O  O   . ALA A 1 521 ? 108.774 86.581  86.790  1.00 97.97 ? 509 ALA A O   1 
ATOM   3697 C  CB  . ALA A 1 521 ? 111.621 85.102  87.160  1.00 97.97 ? 509 ALA A CB  1 
ATOM   3698 N  N   . VAL A 1 522 ? 108.850 85.352  88.658  1.00 97.48 ? 510 VAL A N   1 
ATOM   3699 C  CA  . VAL A 1 522 ? 107.429 85.029  88.580  1.00 97.48 ? 510 VAL A CA  1 
ATOM   3700 C  C   . VAL A 1 522 ? 106.562 85.456  89.746  1.00 97.48 ? 510 VAL A C   1 
ATOM   3701 O  O   . VAL A 1 522 ? 105.587 86.160  89.556  1.00 97.48 ? 510 VAL A O   1 
ATOM   3702 C  CB  . VAL A 1 522 ? 107.224 83.501  88.382  1.00 97.48 ? 510 VAL A CB  1 
ATOM   3703 C  CG1 . VAL A 1 522 ? 105.756 83.172  88.165  1.00 97.48 ? 510 VAL A CG1 1 
ATOM   3704 C  CG2 . VAL A 1 522 ? 108.058 82.981  87.223  1.00 97.48 ? 510 VAL A CG2 1 
ATOM   3705 N  N   . ILE A 1 523 ? 106.911 85.062  90.958  1.00 97.01 ? 511 ILE A N   1 
ATOM   3706 C  CA  . ILE A 1 523 ? 106.023 85.336  92.082  1.00 97.01 ? 511 ILE A CA  1 
ATOM   3707 C  C   . ILE A 1 523 ? 105.779 86.798  92.383  1.00 97.01 ? 511 ILE A C   1 
ATOM   3708 O  O   . ILE A 1 523 ? 104.642 87.197  92.556  1.00 97.01 ? 511 ILE A O   1 
ATOM   3709 C  CB  . ILE A 1 523 ? 106.517 84.631  93.360  1.00 97.01 ? 511 ILE A CB  1 
ATOM   3710 C  CG1 . ILE A 1 523 ? 106.952 83.201  93.041  1.00 97.01 ? 511 ILE A CG1 1 
ATOM   3711 C  CG2 . ILE A 1 523 ? 105.442 84.633  94.433  1.00 97.01 ? 511 ILE A CG2 1 
ATOM   3712 C  CD1 . ILE A 1 523 ? 107.467 82.442  94.242  1.00 97.01 ? 511 ILE A CD1 1 
ATOM   3713 N  N   . THR A 1 524 ? 106.818 87.616  92.418  1.00 96.03 ? 512 THR A N   1 
ATOM   3714 C  CA  . THR A 1 524 ? 106.594 89.043  92.609  1.00 96.03 ? 512 THR A CA  1 
ATOM   3715 C  C   . THR A 1 524 ? 105.858 89.702  91.442  1.00 96.03 ? 512 THR A C   1 
ATOM   3716 O  O   . THR A 1 524 ? 104.931 90.469  91.664  1.00 96.03 ? 512 THR A O   1 
ATOM   3717 C  CB  . THR A 1 524 ? 107.882 89.801  92.972  1.00 96.03 ? 512 THR A CB  1 
ATOM   3718 O  OG1 . THR A 1 524 ? 108.612 89.063  93.958  1.00 96.03 ? 512 THR A OG1 1 
ATOM   3719 C  CG2 . THR A 1 524 ? 107.554 91.184  93.511  1.00 96.03 ? 512 THR A CG2 1 
ATOM   3720 N  N   . PRO A 1 525 ? 106.238 89.387  90.190  1.00 96.51 ? 513 PRO A N   1 
ATOM   3721 C  CA  . PRO A 1 525 ? 105.447 89.956  89.104  1.00 96.51 ? 513 PRO A CA  1 
ATOM   3722 C  C   . PRO A 1 525 ? 103.983 89.561  89.164  1.00 96.51 ? 513 PRO A C   1 
ATOM   3723 O  O   . PRO A 1 525 ? 103.135 90.433  89.082  1.00 96.51 ? 513 PRO A O   1 
ATOM   3724 C  CB  . PRO A 1 525 ? 106.107 89.363  87.877  1.00 96.51 ? 513 PRO A CB  1 
ATOM   3725 C  CG  . PRO A 1 525 ? 107.536 89.354  88.248  1.00 96.51 ? 513 PRO A CG  1 
ATOM   3726 C  CD  . PRO A 1 525 ? 107.536 88.909  89.683  1.00 96.51 ? 513 PRO A CD  1 
ATOM   3727 N  N   . VAL A 1 526 ? 103.684 88.282  89.314  1.00 95.72 ? 514 VAL A N   1 
ATOM   3728 C  CA  . VAL A 1 526 ? 102.303 87.830  89.322  1.00 95.72 ? 514 VAL A CA  1 
ATOM   3729 C  C   . VAL A 1 526 ? 101.534 88.395  90.507  1.00 95.72 ? 514 VAL A C   1 
ATOM   3730 O  O   . VAL A 1 526 ? 100.422 88.877  90.345  1.00 95.72 ? 514 VAL A O   1 
ATOM   3731 C  CB  . VAL A 1 526 ? 102.210 86.289  89.300  1.00 95.72 ? 514 VAL A CB  1 
ATOM   3732 C  CG1 . VAL A 1 526 ? 100.812 85.809  89.654  1.00 95.72 ? 514 VAL A CG1 1 
ATOM   3733 C  CG2 . VAL A 1 526 ? 102.623 85.759  87.937  1.00 95.72 ? 514 VAL A CG2 1 
ATOM   3734 N  N   . LEU A 1 527 ? 102.136 88.393  91.687  1.00 92.20 ? 515 LEU A N   1 
ATOM   3735 C  CA  . LEU A 1 527 ? 101.468 88.969  92.843  1.00 92.20 ? 515 LEU A CA  1 
ATOM   3736 C  C   . LEU A 1 527 ? 101.217 90.464  92.715  1.00 92.20 ? 515 LEU A C   1 
ATOM   3737 O  O   . LEU A 1 527 ? 100.133 90.929  93.028  1.00 92.20 ? 515 LEU A O   1 
ATOM   3738 C  CB  . LEU A 1 527 ? 102.244 88.685  94.131  1.00 92.20 ? 515 LEU A CB  1 
ATOM   3739 C  CG  . LEU A 1 527 ? 102.075 87.326  94.809  1.00 92.20 ? 515 LEU A CG  1 
ATOM   3740 C  CD1 . LEU A 1 527 ? 102.957 87.250  96.044  1.00 92.20 ? 515 LEU A CD1 1 
ATOM   3741 C  CD2 . LEU A 1 527 ? 100.620 87.096  95.180  1.00 92.20 ? 515 LEU A CD2 1 
ATOM   3742 N  N   . CYS A 1 528 ? 102.204 91.224  92.257  1.00 91.91 ? 516 CYS A N   1 
ATOM   3743 C  CA  . CYS A 1 528 ? 101.990 92.653  92.051  1.00 91.91 ? 516 CYS A CA  1 
ATOM   3744 C  C   . CYS A 1 528 ? 100.990 92.993  90.954  1.00 91.91 ? 516 CYS A C   1 
ATOM   3745 O  O   . CYS A 1 528 ? 100.108 93.818  91.159  1.00 91.91 ? 516 CYS A O   1 
ATOM   3746 C  CB  . CYS A 1 528 ? 103.319 93.351  91.770  1.00 91.91 ? 516 CYS A CB  1 
ATOM   3747 S  SG  . CYS A 1 528 ? 104.433 93.413  93.192  1.00 91.91 ? 516 CYS A SG  1 
ATOM   3748 N  N   . VAL A 1 529 ? 101.143 92.393  89.781  1.00 92.81 ? 517 VAL A N   1 
ATOM   3749 C  CA  . VAL A 1 529 ? 100.242 92.672  88.670  1.00 92.81 ? 517 VAL A CA  1 
ATOM   3750 C  C   . VAL A 1 529 ? 98.848  92.148  88.962  1.00 92.81 ? 517 VAL A C   1 
ATOM   3751 O  O   . VAL A 1 529 ? 97.861  92.831  88.714  1.00 92.81 ? 517 VAL A O   1 
ATOM   3752 C  CB  . VAL A 1 529 ? 100.775 92.088  87.348  1.00 92.81 ? 517 VAL A CB  1 
ATOM   3753 C  CG1 . VAL A 1 529 ? 99.742  92.199  86.240  1.00 92.81 ? 517 VAL A CG1 1 
ATOM   3754 C  CG2 . VAL A 1 529 ? 102.047 92.804  86.940  1.00 92.81 ? 517 VAL A CG2 1 
ATOM   3755 N  N   . GLY A 1 530 ? 98.757  90.951  89.520  1.00 90.50 ? 518 GLY A N   1 
ATOM   3756 C  CA  . GLY A 1 530 ? 97.462  90.367  89.799  1.00 90.50 ? 518 GLY A CA  1 
ATOM   3757 C  C   . GLY A 1 530 ? 96.670  91.175  90.787  1.00 90.50 ? 518 GLY A C   1 
ATOM   3758 O  O   . GLY A 1 530 ? 95.485  91.374  90.585  1.00 90.50 ? 518 GLY A O   1 
ATOM   3759 N  N   . CYS A 1 531 ? 97.310  91.650  91.846  1.00 88.16 ? 519 CYS A N   1 
ATOM   3760 C  CA  . CYS A 1 531 ? 96.639  92.507  92.820  1.00 88.16 ? 519 CYS A CA  1 
ATOM   3761 C  C   . CYS A 1 531 ? 96.197  93.836  92.225  1.00 88.16 ? 519 CYS A C   1 
ATOM   3762 O  O   . CYS A 1 531 ? 95.118  94.327  92.540  1.00 88.16 ? 519 CYS A O   1 
ATOM   3763 C  CB  . CYS A 1 531 ? 97.524  92.736  94.045  1.00 88.16 ? 519 CYS A CB  1 
ATOM   3764 S  SG  . CYS A 1 531 ? 97.667  91.298  95.125  1.00 88.16 ? 519 CYS A SG  1 
ATOM   3765 N  N   . PHE A 1 532 ? 97.026  94.429  91.376  1.00 88.01 ? 520 PHE A N   1 
ATOM   3766 C  CA  . PHE A 1 532 ? 96.656  95.676  90.727  1.00 88.01 ? 520 PHE A CA  1 
ATOM   3767 C  C   . PHE A 1 532 ? 95.431  95.504  89.840  1.00 88.01 ? 520 PHE A C   1 
ATOM   3768 O  O   . PHE A 1 532 ? 94.510  96.310  89.900  1.00 88.01 ? 520 PHE A O   1 
ATOM   3769 C  CB  . PHE A 1 532 ? 97.846  96.180  89.910  1.00 88.01 ? 520 PHE A CB  1 
ATOM   3770 C  CG  . PHE A 1 532 ? 97.538  97.352  89.024  1.00 88.01 ? 520 PHE A CG  1 
ATOM   3771 C  CD1 . PHE A 1 532 ? 97.350  98.612  89.560  1.00 88.01 ? 520 PHE A CD1 1 
ATOM   3772 C  CD2 . PHE A 1 532 ? 97.473  97.198  87.649  1.00 88.01 ? 520 PHE A CD2 1 
ATOM   3773 C  CE1 . PHE A 1 532 ? 97.078  99.695  88.748  1.00 88.01 ? 520 PHE A CE1 1 
ATOM   3774 C  CE2 . PHE A 1 532 ? 97.201  98.275  86.830  1.00 88.01 ? 520 PHE A CE2 1 
ATOM   3775 C  CZ  . PHE A 1 532 ? 97.005  99.527  87.381  1.00 88.01 ? 520 PHE A CZ  1 
ATOM   3776 N  N   . ILE A 1 533 ? 95.398  94.452  89.036  1.00 90.64 ? 521 ILE A N   1 
ATOM   3777 C  CA  . ILE A 1 533 ? 94.247  94.201  88.184  1.00 90.64 ? 521 ILE A CA  1 
ATOM   3778 C  C   . ILE A 1 533 ? 93.027  93.863  89.021  1.00 90.64 ? 521 ILE A C   1 
ATOM   3779 O  O   . ILE A 1 533 ? 91.934  94.327  88.734  1.00 90.64 ? 521 ILE A O   1 
ATOM   3780 C  CB  . ILE A 1 533 ? 94.536  93.077  87.175  1.00 90.64 ? 521 ILE A CB  1 
ATOM   3781 C  CG1 . ILE A 1 533 ? 95.704  93.470  86.274  1.00 90.64 ? 521 ILE A CG1 1 
ATOM   3782 C  CG2 . ILE A 1 533 ? 93.316  92.773  86.323  1.00 90.64 ? 521 ILE A CG2 1 
ATOM   3783 C  CD1 . ILE A 1 533 ? 96.034  92.433  85.225  1.00 90.64 ? 521 ILE A CD1 1 
ATOM   3784 N  N   . PHE A 1 534 ? 93.209  93.088  90.080  1.00 87.33 ? 522 PHE A N   1 
ATOM   3785 C  CA  . PHE A 1 534 ? 92.088  92.668  90.914  1.00 87.33 ? 522 PHE A CA  1 
ATOM   3786 C  C   . PHE A 1 534 ? 91.431  93.883  91.537  1.00 87.33 ? 522 PHE A C   1 
ATOM   3787 O  O   . PHE A 1 534 ? 90.208  93.971  91.592  1.00 87.33 ? 522 PHE A O   1 
ATOM   3788 C  CB  . PHE A 1 534 ? 92.599  91.717  91.995  1.00 87.33 ? 522 PHE A CB  1 
ATOM   3789 C  CG  . PHE A 1 534 ? 91.531  90.921  92.687  1.00 87.33 ? 522 PHE A CG  1 
ATOM   3790 C  CD1 . PHE A 1 534 ? 90.310  90.682  92.084  1.00 87.33 ? 522 PHE A CD1 1 
ATOM   3791 C  CD2 . PHE A 1 534 ? 91.771  90.380  93.939  1.00 87.33 ? 522 PHE A CD2 1 
ATOM   3792 C  CE1 . PHE A 1 534 ? 89.341  89.939  92.730  1.00 87.33 ? 522 PHE A CE1 1 
ATOM   3793 C  CE2 . PHE A 1 534 ? 90.807  89.638  94.590  1.00 87.33 ? 522 PHE A CE2 1 
ATOM   3794 C  CZ  . PHE A 1 534 ? 89.588  89.417  93.984  1.00 87.33 ? 522 PHE A CZ  1 
ATOM   3795 N  N   . SER A 1 535 ? 92.235  94.835  91.990  1.00 85.09 ? 523 SER A N   1 
ATOM   3796 C  CA  . SER A 1 535 ? 91.692  96.044  92.584  1.00 85.09 ? 523 SER A CA  1 
ATOM   3797 C  C   . SER A 1 535 ? 90.853  96.820  91.588  1.00 85.09 ? 523 SER A C   1 
ATOM   3798 O  O   . SER A 1 535 ? 89.811  97.336  91.943  1.00 85.09 ? 523 SER A O   1 
ATOM   3799 C  CB  . SER A 1 535 ? 92.810  96.922  93.128  1.00 85.09 ? 523 SER A CB  1 
ATOM   3800 O  OG  . SER A 1 535 ? 93.571  97.504  92.090  1.00 85.09 ? 523 SER A OG  1 
ATOM   3801 N  N   . LEU A 1 536 ? 91.299  96.907  90.343  1.00 88.21 ? 524 LEU A N   1 
ATOM   3802 C  CA  . LEU A 1 536 ? 90.568  97.628  89.313  1.00 88.21 ? 524 LEU A CA  1 
ATOM   3803 C  C   . LEU A 1 536 ? 89.293  96.902  88.898  1.00 88.21 ? 524 LEU A C   1 
ATOM   3804 O  O   . LEU A 1 536 ? 88.248  97.528  88.758  1.00 88.21 ? 524 LEU A O   1 
ATOM   3805 C  CB  . LEU A 1 536 ? 91.460  97.890  88.105  1.00 88.21 ? 524 LEU A CB  1 
ATOM   3806 C  CG  . LEU A 1 536 ? 92.697  98.746  88.365  1.00 88.21 ? 524 LEU A CG  1 
ATOM   3807 C  CD1 . LEU A 1 536 ? 93.408  99.021  87.053  1.00 88.21 ? 524 LEU A CD1 1 
ATOM   3808 C  CD2 . LEU A 1 536 ? 92.317  100.048 89.052  1.00 88.21 ? 524 LEU A CD2 1 
ATOM   3809 N  N   . VAL A 1 537 ? 89.369  95.589  88.703  1.00 90.00 ? 525 VAL A N   1 
ATOM   3810 C  CA  . VAL A 1 537 ? 88.186  94.818  88.327  1.00 90.00 ? 525 VAL A CA  1 
ATOM   3811 C  C   . VAL A 1 537 ? 87.116  94.870  89.407  1.00 90.00 ? 525 VAL A C   1 
ATOM   3812 O  O   . VAL A 1 537 ? 85.953  95.139  89.113  1.00 90.00 ? 525 VAL A O   1 
ATOM   3813 C  CB  . VAL A 1 537 ? 88.549  93.348  88.036  1.00 90.00 ? 525 VAL A CB  1 
ATOM   3814 C  CG1 . VAL A 1 537 ? 87.300  92.501  87.853  1.00 90.00 ? 525 VAL A CG1 1 
ATOM   3815 C  CG2 . VAL A 1 537 ? 89.430  93.257  86.803  1.00 90.00 ? 525 VAL A CG2 1 
ATOM   3816 N  N   . LYS A 1 538 ? 87.501  94.639  90.659  1.00 86.42 ? 526 LYS A N   1 
ATOM   3817 C  CA  . LYS A 1 538 ? 86.554  94.741  91.768  1.00 86.42 ? 526 LYS A CA  1 
ATOM   3818 C  C   . LYS A 1 538 ? 86.922  95.962  92.575  1.00 86.42 ? 526 LYS A C   1 
ATOM   3819 O  O   . LYS A 1 538 ? 87.528  95.844  93.633  1.00 86.42 ? 526 LYS A O   1 
ATOM   3820 C  CB  . LYS A 1 538 ? 86.617  93.499  92.645  1.00 86.42 ? 526 LYS A CB  1 
ATOM   3821 C  CG  . LYS A 1 538 ? 86.551  92.190  91.881  1.00 86.42 ? 526 LYS A CG  1 
ATOM   3822 C  CD  . LYS A 1 538 ? 85.663  91.195  92.602  1.00 86.42 ? 526 LYS A CD  1 
ATOM   3823 C  CE  . LYS A 1 538 ? 85.985  91.153  94.085  1.00 86.42 ? 526 LYS A CE  1 
ATOM   3824 N  NZ  . LYS A 1 538 ? 85.077  90.229  94.818  1.00 86.42 ? 526 LYS A NZ  1 
ATOM   3825 N  N   . TYR A 1 539 ? 86.563  97.148  92.087  1.00 87.26 ? 527 TYR A N   1 
ATOM   3826 C  CA  . TYR A 1 539 ? 86.978  98.383  92.762  1.00 87.26 ? 527 TYR A CA  1 
ATOM   3827 C  C   . TYR A 1 539 ? 86.165  98.802  93.974  1.00 87.26 ? 527 TYR A C   1 
ATOM   3828 O  O   . TYR A 1 539 ? 84.948  98.961  93.888  1.00 87.26 ? 527 TYR A O   1 
ATOM   3829 C  CB  . TYR A 1 539 ? 87.060  99.545  91.765  1.00 87.26 ? 527 TYR A CB  1 
ATOM   3830 C  CG  . TYR A 1 539 ? 87.827  100.737 92.296  1.00 87.26 ? 527 TYR A CG  1 
ATOM   3831 C  CD1 . TYR A 1 539 ? 89.215  100.737 92.318  1.00 87.26 ? 527 TYR A CD1 1 
ATOM   3832 C  CD2 . TYR A 1 539 ? 87.164  101.860 92.779  1.00 87.26 ? 527 TYR A CD2 1 
ATOM   3833 C  CE1 . TYR A 1 539 ? 89.922  101.820 92.804  1.00 87.26 ? 527 TYR A CE1 1 
ATOM   3834 C  CE2 . TYR A 1 539 ? 87.864  102.946 93.268  1.00 87.26 ? 527 TYR A CE2 1 
ATOM   3835 C  CZ  . TYR A 1 539 ? 89.242  102.921 93.277  1.00 87.26 ? 527 TYR A CZ  1 
ATOM   3836 O  OH  . TYR A 1 539 ? 89.943  104.000 93.762  1.00 87.26 ? 527 TYR A OH  1 
ATOM   3837 N  N   . VAL A 1 540 ? 86.838  98.988  95.104  1.00 86.16 ? 528 VAL A N   1 
ATOM   3838 C  CA  . VAL A 1 540 ? 86.156  99.468  96.301  1.00 86.16 ? 528 VAL A CA  1 
ATOM   3839 C  C   . VAL A 1 540 ? 86.811  100.785 96.732  1.00 86.16 ? 528 VAL A C   1 
ATOM   3840 O  O   . VAL A 1 540 ? 88.035  100.869 96.844  1.00 86.16 ? 528 VAL A O   1 
ATOM   3841 C  CB  . VAL A 1 540 ? 86.181  98.407  97.427  1.00 86.16 ? 528 VAL A CB  1 
ATOM   3842 C  CG1 . VAL A 1 540 ? 87.604  98.110  97.870  1.00 86.16 ? 528 VAL A CG1 1 
ATOM   3843 C  CG2 . VAL A 1 540 ? 85.299  98.807  98.600  1.00 86.16 ? 528 VAL A CG2 1 
ATOM   3844 N  N   . PRO A 1 541 ? 85.996  101.830 96.945  1.00 89.82 ? 529 PRO A N   1 
ATOM   3845 C  CA  . PRO A 1 541 ? 86.519  103.131 97.382  1.00 89.82 ? 529 PRO A CA  1 
ATOM   3846 C  C   . PRO A 1 541 ? 87.146  103.077 98.773  1.00 89.82 ? 529 PRO A C   1 
ATOM   3847 O  O   . PRO A 1 541 ? 86.660  102.368 99.654  1.00 89.82 ? 529 PRO A O   1 
ATOM   3848 C  CB  . PRO A 1 541 ? 85.274  104.029 97.396  1.00 89.82 ? 529 PRO A CB  1 
ATOM   3849 C  CG  . PRO A 1 541 ? 84.109  103.096 97.410  1.00 89.82 ? 529 PRO A CG  1 
ATOM   3850 C  CD  . PRO A 1 541 ? 84.556  101.886 96.649  1.00 89.82 ? 529 PRO A CD  1 
ATOM   3851 N  N   . LEU A 1 542 ? 88.225  103.828 98.958  1.00 90.92 ? 530 LEU A N   1 
ATOM   3852 C  CA  . LEU A 1 542 ? 88.732  104.129 100.291 1.00 90.92 ? 530 LEU A CA  1 
ATOM   3853 C  C   . LEU A 1 542 ? 87.646  104.690 101.200 1.00 90.92 ? 530 LEU A C   1 
ATOM   3854 O  O   . LEU A 1 542 ? 86.976  105.660 100.846 1.00 90.92 ? 530 LEU A O   1 
ATOM   3855 C  CB  . LEU A 1 542 ? 89.908  105.105 100.207 1.00 90.92 ? 530 LEU A CB  1 
ATOM   3856 C  CG  . LEU A 1 542 ? 90.536  105.558 101.527 1.00 90.92 ? 530 LEU A CG  1 
ATOM   3857 C  CD1 . LEU A 1 542 ? 91.040  104.373 102.337 1.00 90.92 ? 530 LEU A CD1 1 
ATOM   3858 C  CD2 . LEU A 1 542 ? 91.652  106.555 101.273 1.00 90.92 ? 530 LEU A CD2 1 
ATOM   3859 N  N   . THR A 1 543 ? 87.462  104.076 102.366 1.00 90.88 ? 531 THR A N   1 
ATOM   3860 C  CA  . THR A 1 543 ? 86.474  104.561 103.325 1.00 90.88 ? 531 THR A CA  1 
ATOM   3861 C  C   . THR A 1 543 ? 87.127  104.748 104.694 1.00 90.88 ? 531 THR A C   1 
ATOM   3862 O  O   . THR A 1 543 ? 87.814  103.845 105.172 1.00 90.88 ? 531 THR A O   1 
ATOM   3863 C  CB  . THR A 1 543 ? 85.298  103.575 103.479 1.00 90.88 ? 531 THR A CB  1 
ATOM   3864 O  OG1 . THR A 1 543 ? 85.805  102.257 103.723 1.00 90.88 ? 531 THR A OG1 1 
ATOM   3865 C  CG2 . THR A 1 543 ? 84.433  103.556 102.226 1.00 90.88 ? 531 THR A CG2 1 
ATOM   3866 N  N   . TYR A 1 544 ? 86.929  105.903 105.329 1.00 87.96 ? 532 TYR A N   1 
ATOM   3867 C  CA  . TYR A 1 544 ? 87.588  106.121 106.601 1.00 87.96 ? 532 TYR A CA  1 
ATOM   3868 C  C   . TYR A 1 544 ? 86.750  105.552 107.733 1.00 87.96 ? 532 TYR A C   1 
ATOM   3869 O  O   . TYR A 1 544 ? 85.589  105.926 107.878 1.00 87.96 ? 532 TYR A O   1 
ATOM   3870 C  CB  . TYR A 1 544 ? 87.855  107.606 106.826 1.00 87.96 ? 532 TYR A CB  1 
ATOM   3871 C  CG  . TYR A 1 544 ? 88.247  107.940 108.240 1.00 87.96 ? 532 TYR A CG  1 
ATOM   3872 C  CD1 . TYR A 1 544 ? 89.515  107.649 108.713 1.00 87.96 ? 532 TYR A CD1 1 
ATOM   3873 C  CD2 . TYR A 1 544 ? 87.346  108.544 109.103 1.00 87.96 ? 532 TYR A CD2 1 
ATOM   3874 C  CE1 . TYR A 1 544 ? 89.871  107.946 110.009 1.00 87.96 ? 532 TYR A CE1 1 
ATOM   3875 C  CE2 . TYR A 1 544 ? 87.693  108.844 110.400 1.00 87.96 ? 532 TYR A CE2 1 
ATOM   3876 C  CZ  . TYR A 1 544 ? 88.956  108.545 110.848 1.00 87.96 ? 532 TYR A CZ  1 
ATOM   3877 O  OH  . TYR A 1 544 ? 89.299  108.850 112.144 1.00 87.96 ? 532 TYR A OH  1 
ATOM   3878 N  N   . ASN A 1 545 ? 87.308  104.618 108.500 1.00 79.89 ? 533 ASN A N   1 
ATOM   3879 C  CA  . ASN A 1 545 ? 86.620  104.036 109.656 1.00 79.89 ? 533 ASN A CA  1 
ATOM   3880 C  C   . ASN A 1 545 ? 85.349  103.300 109.267 1.00 79.89 ? 533 ASN A C   1 
ATOM   3881 O  O   . ASN A 1 545 ? 84.439  103.203 110.088 1.00 79.89 ? 533 ASN A O   1 
ATOM   3882 C  CB  . ASN A 1 545 ? 86.384  105.073 110.760 1.00 79.89 ? 533 ASN A CB  1 
ATOM   3883 C  CG  . ASN A 1 545 ? 86.383  104.466 112.145 1.00 79.89 ? 533 ASN A CG  1 
ATOM   3884 O  OD1 . ASN A 1 545 ? 86.557  103.261 112.308 1.00 79.89 ? 533 ASN A OD1 1 
ATOM   3885 N  ND2 . ASN A 1 545 ? 86.185  105.302 113.154 1.00 79.89 ? 533 ASN A ND2 1 
ATOM   3886 N  N   . LYS A 1 546 ? 85.238  102.860 108.015 1.00 77.97 ? 534 LYS A N   1 
ATOM   3887 C  CA  . LYS A 1 546 ? 84.101  102.044 107.549 1.00 77.97 ? 534 LYS A CA  1 
ATOM   3888 C  C   . LYS A 1 546 ? 82.794  102.790 107.320 1.00 77.97 ? 534 LYS A C   1 
ATOM   3889 O  O   . LYS A 1 546 ? 81.826  102.196 106.857 1.00 77.97 ? 534 LYS A O   1 
ATOM   3890 C  CB  . LYS A 1 546 ? 83.849  100.819 108.446 1.00 77.97 ? 534 LYS A CB  1 
ATOM   3891 C  CG  . LYS A 1 546 ? 84.967  99.792  108.477 1.00 77.97 ? 534 LYS A CG  1 
ATOM   3892 C  CD  . LYS A 1 546 ? 84.669  98.680  109.468 1.00 77.97 ? 534 LYS A CD  1 
ATOM   3893 C  CE  . LYS A 1 546 ? 83.458  97.866  109.042 1.00 77.97 ? 534 LYS A CE  1 
ATOM   3894 N  NZ  . LYS A 1 546 ? 83.672  97.185  107.734 1.00 77.97 ? 534 LYS A NZ  1 
ATOM   3895 N  N   . THR A 1 547 ? 82.753  104.079 107.630 1.00 85.16 ? 535 THR A N   1 
ATOM   3896 C  CA  . THR A 1 547 ? 81.508  104.832 107.508 1.00 85.16 ? 535 THR A CA  1 
ATOM   3897 C  C   . THR A 1 547 ? 81.615  106.080 106.663 1.00 85.16 ? 535 THR A C   1 
ATOM   3898 O  O   . THR A 1 547 ? 80.604  106.703 106.356 1.00 85.16 ? 535 THR A O   1 
ATOM   3899 C  CB  . THR A 1 547 ? 80.969  105.240 108.887 1.00 85.16 ? 535 THR A CB  1 
ATOM   3900 O  OG1 . THR A 1 547 ? 82.025  105.831 109.653 1.00 85.16 ? 535 THR A OG1 1 
ATOM   3901 C  CG2 . THR A 1 547 ? 80.428  104.032 109.633 1.00 85.16 ? 535 THR A CG2 1 
ATOM   3902 N  N   . TYR A 1 548 ? 82.833  106.491 106.333 1.00 92.20 ? 536 TYR A N   1 
ATOM   3903 C  CA  . TYR A 1 548 ? 83.014  107.721 105.578 1.00 92.20 ? 536 TYR A CA  1 
ATOM   3904 C  C   . TYR A 1 548 ? 83.343  107.442 104.132 1.00 92.20 ? 536 TYR A C   1 
ATOM   3905 O  O   . TYR A 1 548 ? 84.272  106.717 103.839 1.00 92.20 ? 536 TYR A O   1 
ATOM   3906 C  CB  . TYR A 1 548 ? 84.097  108.594 106.203 1.00 92.20 ? 536 TYR A CB  1 
ATOM   3907 C  CG  . TYR A 1 548 ? 84.379  109.856 105.426 1.00 92.20 ? 536 TYR A CG  1 
ATOM   3908 C  CD1 . TYR A 1 548 ? 83.506  110.929 105.477 1.00 92.20 ? 536 TYR A CD1 1 
ATOM   3909 C  CD2 . TYR A 1 548 ? 85.515  109.973 104.639 1.00 92.20 ? 536 TYR A CD2 1 
ATOM   3910 C  CE1 . TYR A 1 548 ? 83.754  112.081 104.765 1.00 92.20 ? 536 TYR A CE1 1 
ATOM   3911 C  CE2 . TYR A 1 548 ? 85.770  111.123 103.924 1.00 92.20 ? 536 TYR A CE2 1 
ATOM   3912 C  CZ  . TYR A 1 548 ? 84.886  112.171 103.994 1.00 92.20 ? 536 TYR A CZ  1 
ATOM   3913 O  OH  . TYR A 1 548 ? 85.134  113.316 103.287 1.00 92.20 ? 536 TYR A OH  1 
ATOM   3914 N  N   . VAL A 1 549 ? 82.590  108.046 103.223 1.00 95.40 ? 537 VAL A N   1 
ATOM   3915 C  CA  . VAL A 1 549 ? 82.875  107.893 101.813 1.00 95.40 ? 537 VAL A CA  1 
ATOM   3916 C  C   . VAL A 1 549 ? 83.589  109.122 101.300 1.00 95.40 ? 537 VAL A C   1 
ATOM   3917 O  O   . VAL A 1 549 ? 83.108  110.241 101.451 1.00 95.40 ? 537 VAL A O   1 
ATOM   3918 C  CB  . VAL A 1 549 ? 81.599  107.621 100.998 1.00 95.40 ? 537 VAL A CB  1 
ATOM   3919 C  CG1 . VAL A 1 549 ? 80.984  106.295 101.413 1.00 95.40 ? 537 VAL A CG1 1 
ATOM   3920 C  CG2 . VAL A 1 549 ? 80.598  108.752 101.174 1.00 95.40 ? 537 VAL A CG2 1 
ATOM   3921 N  N   . TYR A 1 550 ? 84.750  108.917 100.697 1.00 96.51 ? 538 TYR A N   1 
ATOM   3922 C  CA  . TYR A 1 550 ? 85.529  110.042 100.220 1.00 96.51 ? 538 TYR A CA  1 
ATOM   3923 C  C   . TYR A 1 550 ? 84.910  110.685 98.979  1.00 96.51 ? 538 TYR A C   1 
ATOM   3924 O  O   . TYR A 1 550 ? 84.412  109.969 98.113  1.00 96.51 ? 538 TYR A O   1 
ATOM   3925 C  CB  . TYR A 1 550 ? 86.967  109.620 99.940  1.00 96.51 ? 538 TYR A CB  1 
ATOM   3926 C  CG  . TYR A 1 550 ? 87.849  109.613 101.157 1.00 96.51 ? 538 TYR A CG  1 
ATOM   3927 C  CD1 . TYR A 1 550 ? 87.865  108.528 102.015 1.00 96.51 ? 538 TYR A CD1 1 
ATOM   3928 C  CD2 . TYR A 1 550 ? 88.665  110.692 101.449 1.00 96.51 ? 538 TYR A CD2 1 
ATOM   3929 C  CE1 . TYR A 1 550 ? 88.669  108.516 103.131 1.00 96.51 ? 538 TYR A CE1 1 
ATOM   3930 C  CE2 . TYR A 1 550 ? 89.473  110.689 102.564 1.00 96.51 ? 538 TYR A CE2 1 
ATOM   3931 C  CZ  . TYR A 1 550 ? 89.468  109.595 103.398 1.00 96.51 ? 538 TYR A CZ  1 
ATOM   3932 O  OH  . TYR A 1 550 ? 90.263  109.578 104.508 1.00 96.51 ? 538 TYR A OH  1 
ATOM   3933 N  N   . PRO A 1 551 ? 84.933  112.041 98.870  1.00 97.07 ? 539 PRO A N   1 
ATOM   3934 C  CA  . PRO A 1 551 ? 84.397  112.583 97.620  1.00 97.07 ? 539 PRO A CA  1 
ATOM   3935 C  C   . PRO A 1 551 ? 85.187  112.109 96.412  1.00 97.07 ? 539 PRO A C   1 
ATOM   3936 O  O   . PRO A 1 551 ? 86.323  111.667 96.545  1.00 97.07 ? 539 PRO A O   1 
ATOM   3937 C  CB  . PRO A 1 551 ? 84.577  114.084 97.799  1.00 97.07 ? 539 PRO A CB  1 
ATOM   3938 C  CG  . PRO A 1 551 ? 84.501  114.299 99.261  1.00 97.07 ? 539 PRO A CG  1 
ATOM   3939 C  CD  . PRO A 1 551 ? 85.260  113.139 99.811  1.00 97.07 ? 539 PRO A CD  1 
ATOM   3940 N  N   . ASN A 1 552 ? 84.592  112.192 95.232  1.00 96.75 ? 540 ASN A N   1 
ATOM   3941 C  CA  . ASN A 1 552 ? 85.269  111.728 94.030  1.00 96.75 ? 540 ASN A CA  1 
ATOM   3942 C  C   . ASN A 1 552 ? 86.564  112.495 93.800  1.00 96.75 ? 540 ASN A C   1 
ATOM   3943 O  O   . ASN A 1 552 ? 87.552  111.927 93.338  1.00 96.75 ? 540 ASN A O   1 
ATOM   3944 C  CB  . ASN A 1 552 ? 84.352  111.840 92.816  1.00 96.75 ? 540 ASN A CB  1 
ATOM   3945 C  CG  . ASN A 1 552 ? 83.160  110.911 92.897  1.00 96.75 ? 540 ASN A CG  1 
ATOM   3946 O  OD1 . ASN A 1 552 ? 83.125  109.998 93.720  1.00 96.75 ? 540 ASN A OD1 1 
ATOM   3947 N  ND2 . ASN A 1 552 ? 82.175  111.136 92.037  1.00 96.75 ? 540 ASN A ND2 1 
ATOM   3948 N  N   . TRP A 1 553 ? 86.568  113.780 94.132  1.00 97.43 ? 541 TRP A N   1 
ATOM   3949 C  CA  . TRP A 1 553 ? 87.775  114.577 93.964  1.00 97.43 ? 541 TRP A CA  1 
ATOM   3950 C  C   . TRP A 1 553 ? 88.897  114.059 94.839  1.00 97.43 ? 541 TRP A C   1 
ATOM   3951 O  O   . TRP A 1 553 ? 90.041  114.031 94.414  1.00 97.43 ? 541 TRP A O   1 
ATOM   3952 C  CB  . TRP A 1 553 ? 87.527  116.083 94.177  1.00 97.43 ? 541 TRP A CB  1 
ATOM   3953 C  CG  . TRP A 1 553 ? 87.164  116.529 95.569  1.00 97.43 ? 541 TRP A CG  1 
ATOM   3954 C  CD1 . TRP A 1 553 ? 85.910  116.731 96.058  1.00 97.43 ? 541 TRP A CD1 1 
ATOM   3955 C  CD2 . TRP A 1 553 ? 88.067  116.874 96.632  1.00 97.43 ? 541 TRP A CD2 1 
ATOM   3956 N  NE1 . TRP A 1 553 ? 85.971  117.155 97.362  1.00 97.43 ? 541 TRP A NE1 1 
ATOM   3957 C  CE2 . TRP A 1 553 ? 87.284  117.249 97.738  1.00 97.43 ? 541 TRP A CE2 1 
ATOM   3958 C  CE3 . TRP A 1 553 ? 89.460  116.888 96.757  1.00 97.43 ? 541 TRP A CE3 1 
ATOM   3959 C  CZ2 . TRP A 1 553 ? 87.844  117.634 98.950  1.00 97.43 ? 541 TRP A CZ2 1 
ATOM   3960 C  CZ3 . TRP A 1 553 ? 90.012  117.266 97.962  1.00 97.43 ? 541 TRP A CZ3 1 
ATOM   3961 C  CH2 . TRP A 1 553 ? 89.207  117.637 99.041  1.00 97.43 ? 541 TRP A CH2 1 
ATOM   3962 N  N   . ALA A 1 554 ? 88.576  113.657 96.063  1.00 97.59 ? 542 ALA A N   1 
ATOM   3963 C  CA  . ALA A 1 554 ? 89.585  113.159 96.981  1.00 97.59 ? 542 ALA A CA  1 
ATOM   3964 C  C   . ALA A 1 554 ? 90.221  111.888 96.464  1.00 97.59 ? 542 ALA A C   1 
ATOM   3965 O  O   . ALA A 1 554 ? 91.429  111.724 96.559  1.00 97.59 ? 542 ALA A O   1 
ATOM   3966 C  CB  . ALA A 1 554 ? 88.980  112.944 98.351  1.00 97.59 ? 542 ALA A CB  1 
ATOM   3967 N  N   . ILE A 1 555 ? 89.419  110.991 95.905  1.00 96.71 ? 543 ILE A N   1 
ATOM   3968 C  CA  . ILE A 1 555 ? 89.955  109.760 95.331  1.00 96.71 ? 543 ILE A CA  1 
ATOM   3969 C  C   . ILE A 1 555 ? 90.876  110.082 94.163  1.00 96.71 ? 543 ILE A C   1 
ATOM   3970 O  O   . ILE A 1 555 ? 91.947  109.499 94.050  1.00 96.71 ? 543 ILE A O   1 
ATOM   3971 C  CB  . ILE A 1 555 ? 88.826  108.808 94.898  1.00 96.71 ? 543 ILE A CB  1 
ATOM   3972 C  CG1 . ILE A 1 555 ? 87.965  108.430 96.102  1.00 96.71 ? 543 ILE A CG1 1 
ATOM   3973 C  CG2 . ILE A 1 555 ? 89.383  107.551 94.256  1.00 96.71 ? 543 ILE A CG2 1 
ATOM   3974 C  CD1 . ILE A 1 555 ? 88.726  107.693 97.182  1.00 96.71 ? 543 ILE A CD1 1 
ATOM   3975 N  N   . GLY A 1 556 ? 90.488  111.028 93.313  1.00 96.87 ? 544 GLY A N   1 
ATOM   3976 C  CA  . GLY A 1 556 ? 91.345  111.442 92.214  1.00 96.87 ? 544 GLY A CA  1 
ATOM   3977 C  C   . GLY A 1 556 ? 92.633  112.067 92.691  1.00 96.87 ? 544 GLY A C   1 
ATOM   3978 O  O   . GLY A 1 556 ? 93.680  111.825 92.110  1.00 96.87 ? 544 GLY A O   1 
ATOM   3979 N  N   . LEU A 1 557 ? 92.568  112.891 93.731  1.00 96.52 ? 545 LEU A N   1 
ATOM   3980 C  CA  . LEU A 1 557 ? 93.767  113.483 94.313  1.00 96.52 ? 545 LEU A CA  1 
ATOM   3981 C  C   . LEU A 1 557 ? 94.663  112.401 94.895  1.00 96.52 ? 545 LEU A C   1 
ATOM   3982 O  O   . LEU A 1 557 ? 95.883  112.465 94.758  1.00 96.52 ? 545 LEU A O   1 
ATOM   3983 C  CB  . LEU A 1 557 ? 93.377  114.492 95.392  1.00 96.52 ? 545 LEU A CB  1 
ATOM   3984 C  CG  . LEU A 1 557 ? 94.448  115.014 96.353  1.00 96.52 ? 545 LEU A CG  1 
ATOM   3985 C  CD1 . LEU A 1 557 ? 95.416  115.946 95.640  1.00 96.52 ? 545 LEU A CD1 1 
ATOM   3986 C  CD2 . LEU A 1 557 ? 93.803  115.714 97.538  1.00 96.52 ? 545 LEU A CD2 1 
ATOM   3987 N  N   . GLY A 1 558 ? 94.076  111.406 95.549  1.00 96.36 ? 546 GLY A N   1 
ATOM   3988 C  CA  . GLY A 1 558 ? 94.859  110.302 96.060  1.00 96.36 ? 546 GLY A CA  1 
ATOM   3989 C  C   . GLY A 1 558 ? 95.506  109.543 94.932  1.00 96.36 ? 546 GLY A C   1 
ATOM   3990 O  O   . GLY A 1 558 ? 96.660  109.156 95.017  1.00 96.36 ? 546 GLY A O   1 
ATOM   3991 N  N   . TRP A 1 559 ? 94.774  109.341 93.853  1.00 95.94 ? 547 TRP A N   1 
ATOM   3992 C  CA  . TRP A 1 559 ? 95.337  108.671 92.698  1.00 95.94 ? 547 TRP A CA  1 
ATOM   3993 C  C   . TRP A 1 559 ? 96.492  109.452 92.117  1.00 95.94 ? 547 TRP A C   1 
ATOM   3994 O  O   . TRP A 1 559 ? 97.442  108.861 91.654  1.00 95.94 ? 547 TRP A O   1 
ATOM   3995 C  CB  . TRP A 1 559 ? 94.279  108.379 91.645  1.00 95.94 ? 547 TRP A CB  1 
ATOM   3996 C  CG  . TRP A 1 559 ? 93.616  107.062 91.857  1.00 95.94 ? 547 TRP A CG  1 
ATOM   3997 C  CD1 . TRP A 1 559 ? 92.367  106.843 92.347  1.00 95.94 ? 547 TRP A CD1 1 
ATOM   3998 C  CD2 . TRP A 1 559 ? 94.180  105.773 91.603  1.00 95.94 ? 547 TRP A CD2 1 
ATOM   3999 N  NE1 . TRP A 1 559 ? 92.110  105.497 92.407  1.00 95.94 ? 547 TRP A NE1 1 
ATOM   4000 C  CE2 . TRP A 1 559 ? 93.209  104.817 91.955  1.00 95.94 ? 547 TRP A CE2 1 
ATOM   4001 C  CE3 . TRP A 1 559 ? 95.411  105.334 91.107  1.00 95.94 ? 547 TRP A CE3 1 
ATOM   4002 C  CZ2 . TRP A 1 559 ? 93.429  103.451 91.826  1.00 95.94 ? 547 TRP A CZ2 1 
ATOM   4003 C  CZ3 . TRP A 1 559 ? 95.626  103.981 90.980  1.00 95.94 ? 547 TRP A CZ3 1 
ATOM   4004 C  CH2 . TRP A 1 559 ? 94.642  103.053 91.338  1.00 95.94 ? 547 TRP A CH2 1 
ATOM   4005 N  N   . SER A 1 560 ? 96.413  110.774 92.123  1.00 97.69 ? 548 SER A N   1 
ATOM   4006 C  CA  . SER A 1 560 ? 97.512  111.602 91.650  1.00 97.69 ? 548 SER A CA  1 
ATOM   4007 C  C   . SER A 1 560 ? 98.766  111.404 92.483  1.00 97.69 ? 548 SER A C   1 
ATOM   4008 O  O   . SER A 1 560 ? 99.864  111.411 91.946  1.00 97.69 ? 548 SER A O   1 
ATOM   4009 C  CB  . SER A 1 560 ? 97.101  113.066 91.659  1.00 97.69 ? 548 SER A CB  1 
ATOM   4010 O  OG  . SER A 1 560 ? 95.927  113.263 90.896  1.00 97.69 ? 548 SER A OG  1 
ATOM   4011 N  N   . LEU A 1 561 ? 98.621  111.256 93.795  1.00 96.84 ? 549 LEU A N   1 
ATOM   4012 C  CA  . LEU A 1 561 ? 99.776  110.983 94.650  1.00 96.84 ? 549 LEU A CA  1 
ATOM   4013 C  C   . LEU A 1 561 ? 100.403 109.657 94.279  1.00 96.84 ? 549 LEU A C   1 
ATOM   4014 O  O   . LEU A 1 561 ? 101.624 109.541 94.228  1.00 96.84 ? 549 LEU A O   1 
ATOM   4015 C  CB  . LEU A 1 561 ? 99.363  110.939 96.117  1.00 96.84 ? 549 LEU A CB  1 
ATOM   4016 C  CG  . LEU A 1 561 ? 98.691  112.155 96.752  1.00 96.84 ? 549 LEU A CG  1 
ATOM   4017 C  CD1 . LEU A 1 561 ? 98.108  111.785 98.107  1.00 96.84 ? 549 LEU A CD1 1 
ATOM   4018 C  CD2 . LEU A 1 561 ? 99.668  113.311 96.875  1.00 96.84 ? 549 LEU A CD2 1 
ATOM   4019 N  N   . ALA A 1 562 ? 99.584  108.641 94.045  1.00 96.07 ? 550 ALA A N   1 
ATOM   4020 C  CA  . ALA A 1 562 ? 100.106 107.363 93.590  1.00 96.07 ? 550 ALA A CA  1 
ATOM   4021 C  C   . ALA A 1 562 ? 100.705 107.490 92.213  1.00 96.07 ? 550 ALA A C   1 
ATOM   4022 O  O   . ALA A 1 562 ? 101.789 106.991 91.966  1.00 96.07 ? 550 ALA A O   1 
ATOM   4023 C  CB  . ALA A 1 562 ? 98.999  106.337 93.576  1.00 96.07 ? 550 ALA A CB  1 
ATOM   4024 N  N   . LEU A 1 563 ? 100.022 108.190 91.319  1.00 97.20 ? 551 LEU A N   1 
ATOM   4025 C  CA  . LEU A 1 563 ? 100.482 108.341 89.937  1.00 97.20 ? 551 LEU A CA  1 
ATOM   4026 C  C   . LEU A 1 563 ? 101.777 109.090 89.748  1.00 97.20 ? 551 LEU A C   1 
ATOM   4027 O  O   . LEU A 1 563 ? 102.505 108.797 88.825  1.00 97.20 ? 551 LEU A O   1 
ATOM   4028 C  CB  . LEU A 1 563 ? 99.397  108.922 89.035  1.00 97.20 ? 551 LEU A CB  1 
ATOM   4029 C  CG  . LEU A 1 563 ? 98.278  107.964 88.630  1.00 97.20 ? 551 LEU A CG  1 
ATOM   4030 C  CD1 . LEU A 1 563 ? 97.241  108.679 87.781  1.00 97.20 ? 551 LEU A CD1 1 
ATOM   4031 C  CD2 . LEU A 1 563 ? 98.838  106.758 87.897  1.00 97.20 ? 551 LEU A CD2 1 
ATOM   4032 N  N   . SER A 1 564 ? 102.059 110.087 90.574  1.00 97.73 ? 552 SER A N   1 
ATOM   4033 C  CA  . SER A 1 564 ? 103.252 110.888 90.358  1.00 97.73 ? 552 SER A CA  1 
ATOM   4034 C  C   . SER A 1 564 ? 104.471 110.003 90.419  1.00 97.73 ? 552 SER A C   1 
ATOM   4035 O  O   . SER A 1 564 ? 105.340 110.082 89.551  1.00 97.73 ? 552 SER A O   1 
ATOM   4036 C  CB  . SER A 1 564 ? 103.345 111.958 91.436  1.00 97.73 ? 552 SER A CB  1 
ATOM   4037 O  OG  . SER A 1 564 ? 103.198 111.396 92.725  1.00 97.73 ? 552 SER A OG  1 
ATOM   4038 N  N   . SER A 1 565 ? 104.539 109.131 91.415  1.00 97.69 ? 553 SER A N   1 
ATOM   4039 C  CA  . SER A 1 565 ? 105.628 108.173 91.477  1.00 97.69 ? 553 SER A CA  1 
ATOM   4040 C  C   . SER A 1 565 ? 105.552 107.171 90.354  1.00 97.69 ? 553 SER A C   1 
ATOM   4041 O  O   . SER A 1 565 ? 106.546 106.868 89.720  1.00 97.69 ? 553 SER A O   1 
ATOM   4042 C  CB  . SER A 1 565 ? 105.585 107.448 92.804  1.00 97.69 ? 553 SER A CB  1 
ATOM   4043 O  OG  . SER A 1 565 ? 104.258 107.175 93.200  1.00 97.69 ? 553 SER A OG  1 
ATOM   4044 N  N   . MET A 1 566 ? 104.361 106.673 90.075  1.00 96.90 ? 554 MET A N   1 
ATOM   4045 C  CA  . MET A 1 566 ? 104.206 105.657 89.055  1.00 96.90 ? 554 MET A CA  1 
ATOM   4046 C  C   . MET A 1 566 ? 104.596 106.172 87.698  1.00 96.90 ? 554 MET A C   1 
ATOM   4047 O  O   . MET A 1 566 ? 105.224 105.460 86.940  1.00 96.90 ? 554 MET A O   1 
ATOM   4048 C  CB  . MET A 1 566 ? 102.771 105.135 89.042  1.00 96.90 ? 554 MET A CB  1 
ATOM   4049 C  CG  . MET A 1 566 ? 102.426 104.282 90.247  1.00 96.90 ? 554 MET A CG  1 
ATOM   4050 S  SD  . MET A 1 566 ? 100.659 104.001 90.435  1.00 96.90 ? 554 MET A SD  1 
ATOM   4051 C  CE  . MET A 1 566 ? 100.257 103.276 88.853  1.00 96.90 ? 554 MET A CE  1 
ATOM   4052 N  N   . LEU A 1 567 ? 104.242 107.410 87.391  1.00 98.00 ? 555 LEU A N   1 
ATOM   4053 C  CA  . LEU A 1 567 ? 104.541 107.999 86.092  1.00 98.00 ? 555 LEU A CA  1 
ATOM   4054 C  C   . LEU A 1 567 ? 106.019 108.223 85.847  1.00 98.00 ? 555 LEU A C   1 
ATOM   4055 O  O   . LEU A 1 567 ? 106.438 108.357 84.706  1.00 98.00 ? 555 LEU A O   1 
ATOM   4056 C  CB  . LEU A 1 567 ? 103.760 109.291 85.869  1.00 98.00 ? 555 LEU A CB  1 
ATOM   4057 C  CG  . LEU A 1 567 ? 102.550 109.207 84.938  1.00 98.00 ? 555 LEU A CG  1 
ATOM   4058 C  CD1 . LEU A 1 567 ? 102.974 108.709 83.567  1.00 98.00 ? 555 LEU A CD1 1 
ATOM   4059 C  CD2 . LEU A 1 567 ? 101.465 108.311 85.510  1.00 98.00 ? 555 LEU A CD2 1 
ATOM   4060 N  N   . CYS A 1 568 ? 106.814 108.294 86.903  1.00 98.48 ? 556 CYS A N   1 
ATOM   4061 C  CA  . CYS A 1 568 ? 108.225 108.571 86.728  1.00 98.48 ? 556 CYS A CA  1 
ATOM   4062 C  C   . CYS A 1 568 ? 108.898 107.499 85.877  1.00 98.48 ? 556 CYS A C   1 
ATOM   4063 O  O   . CYS A 1 568 ? 109.706 107.821 85.021  1.00 98.48 ? 556 CYS A O   1 
ATOM   4064 C  CB  . CYS A 1 568 ? 108.931 108.685 88.075  1.00 98.48 ? 556 CYS A CB  1 
ATOM   4065 S  SG  . CYS A 1 568 ? 108.565 110.183 89.006  1.00 98.48 ? 556 CYS A SG  1 
ATOM   4066 N  N   . VAL A 1 569 ? 108.533 106.237 86.087  1.00 98.25 ? 557 VAL A N   1 
ATOM   4067 C  CA  . VAL A 1 569 ? 109.093 105.141 85.293  1.00 98.25 ? 557 VAL A CA  1 
ATOM   4068 C  C   . VAL A 1 569 ? 108.775 105.280 83.797  1.00 98.25 ? 557 VAL A C   1 
ATOM   4069 O  O   . VAL A 1 569 ? 109.692 105.283 82.985  1.00 98.25 ? 557 VAL A O   1 
ATOM   4070 C  CB  . VAL A 1 569 ? 108.717 103.748 85.859  1.00 98.25 ? 557 VAL A CB  1 
ATOM   4071 C  CG1 . VAL A 1 569 ? 109.576 102.663 85.229  1.00 98.25 ? 557 VAL A CG1 1 
ATOM   4072 C  CG2 . VAL A 1 569 ? 108.858 103.734 87.371  1.00 98.25 ? 557 VAL A CG2 1 
ATOM   4073 N  N   . PRO A 1 570 ? 107.473 105.382 83.397  1.00 98.15 ? 558 PRO A N   1 
ATOM   4074 C  CA  . PRO A 1 570 ? 107.293 105.563 81.945  1.00 98.15 ? 558 PRO A CA  1 
ATOM   4075 C  C   . PRO A 1 570 ? 107.858 106.874 81.407  1.00 98.15 ? 558 PRO A C   1 
ATOM   4076 O  O   . PRO A 1 570 ? 108.385 106.880 80.298  1.00 98.15 ? 558 PRO A O   1 
ATOM   4077 C  CB  . PRO A 1 570 ? 105.774 105.552 81.773  1.00 98.15 ? 558 PRO A CB  1 
ATOM   4078 C  CG  . PRO A 1 570 ? 105.294 104.696 82.882  1.00 98.15 ? 558 PRO A CG  1 
ATOM   4079 C  CD  . PRO A 1 570 ? 106.163 105.097 84.031  1.00 98.15 ? 558 PRO A CD  1 
ATOM   4080 N  N   . LEU A 1 571 ? 107.748 107.965 82.158  1.00 98.18 ? 559 LEU A N   1 
ATOM   4081 C  CA  . LEU A 1 571 ? 108.199 109.259 81.647  1.00 98.18 ? 559 LEU A CA  1 
ATOM   4082 C  C   . LEU A 1 571 ? 109.692 109.300 81.360  1.00 98.18 ? 559 LEU A C   1 
ATOM   4083 O  O   . LEU A 1 571 ? 110.111 109.832 80.337  1.00 98.18 ? 559 LEU A O   1 
ATOM   4084 C  CB  . LEU A 1 571 ? 107.831 110.392 82.606  1.00 98.18 ? 559 LEU A CB  1 
ATOM   4085 C  CG  . LEU A 1 571 ? 106.374 110.852 82.570  1.00 98.18 ? 559 LEU A CG  1 
ATOM   4086 C  CD1 . LEU A 1 571 ? 106.144 111.970 83.574  1.00 98.18 ? 559 LEU A CD1 1 
ATOM   4087 C  CD2 . LEU A 1 571 ? 105.989 111.292 81.166  1.00 98.18 ? 559 LEU A CD2 1 
ATOM   4088 N  N   . VAL A 1 572 ? 110.492 108.730 82.252  1.00 98.08 ? 560 VAL A N   1 
ATOM   4089 C  CA  . VAL A 1 572 ? 111.932 108.724 82.049  1.00 98.08 ? 560 VAL A CA  1 
ATOM   4090 C  C   . VAL A 1 572 ? 112.269 107.864 80.840  1.00 98.08 ? 560 VAL A C   1 
ATOM   4091 O  O   . VAL A 1 572 ? 113.123 108.234 80.043  1.00 98.08 ? 560 VAL A O   1 
ATOM   4092 C  CB  . VAL A 1 572 ? 112.694 108.276 83.312  1.00 98.08 ? 560 VAL A CB  1 
ATOM   4093 C  CG1 . VAL A 1 572 ? 114.170 108.097 83.011  1.00 98.08 ? 560 VAL A CG1 1 
ATOM   4094 C  CG2 . VAL A 1 572 ? 112.522 109.312 84.412  1.00 98.08 ? 560 VAL A CG2 1 
ATOM   4095 N  N   . ILE A 1 573 ? 111.591 106.731 80.682  1.00 98.12 ? 561 ILE A N   1 
ATOM   4096 C  CA  . ILE A 1 573 ? 111.800 105.899 79.505  1.00 98.12 ? 561 ILE A CA  1 
ATOM   4097 C  C   . ILE A 1 573 ? 111.694 106.766 78.260  1.00 98.12 ? 561 ILE A C   1 
ATOM   4098 O  O   . ILE A 1 573 ? 112.574 106.731 77.406  1.00 98.12 ? 561 ILE A O   1 
ATOM   4099 C  CB  . ILE A 1 573 ? 110.781 104.745 79.441  1.00 98.12 ? 561 ILE A CB  1 
ATOM   4100 C  CG1 . ILE A 1 573 ? 111.092 103.697 80.506  1.00 98.12 ? 561 ILE A CG1 1 
ATOM   4101 C  CG2 . ILE A 1 573 ? 110.771 104.091 78.070  1.00 98.12 ? 561 ILE A CG2 1 
ATOM   4102 C  CD1 . ILE A 1 573 ? 110.126 102.536 80.522  1.00 98.12 ? 561 ILE A CD1 1 
ATOM   4103 N  N   . VAL A 1 574 ? 110.638 107.568 78.166  1.00 97.93 ? 562 VAL A N   1 
ATOM   4104 C  CA  . VAL A 1 574 ? 110.454 108.439 77.008  1.00 97.93 ? 562 VAL A CA  1 
ATOM   4105 C  C   . VAL A 1 574 ? 111.592 109.438 76.877  1.00 97.93 ? 562 VAL A C   1 
ATOM   4106 O  O   . VAL A 1 574 ? 112.110 109.651 75.787  1.00 97.93 ? 562 VAL A O   1 
ATOM   4107 C  CB  . VAL A 1 574 ? 109.117 109.193 77.087  1.00 97.93 ? 562 VAL A CB  1 
ATOM   4108 C  CG1 . VAL A 1 574 ? 108.902 110.040 75.844  1.00 97.93 ? 562 VAL A CG1 1 
ATOM   4109 C  CG2 . VAL A 1 574 ? 107.971 108.210 77.254  1.00 97.93 ? 562 VAL A CG2 1 
ATOM   4110 N  N   . ILE A 1 575 ? 112.012 110.023 77.991  1.00 97.47 ? 563 ILE A N   1 
ATOM   4111 C  CA  . ILE A 1 575 ? 113.106 110.986 77.967  1.00 97.47 ? 563 ILE A CA  1 
ATOM   4112 C  C   . ILE A 1 575 ? 114.388 110.318 77.493  1.00 97.47 ? 563 ILE A C   1 
ATOM   4113 O  O   . ILE A 1 575 ? 115.121 110.885 76.686  1.00 97.47 ? 563 ILE A O   1 
ATOM   4114 C  CB  . ILE A 1 575 ? 113.310 111.627 79.355  1.00 97.47 ? 563 ILE A CB  1 
ATOM   4115 C  CG1 . ILE A 1 575 ? 112.019 112.292 79.827  1.00 97.47 ? 563 ILE A CG1 1 
ATOM   4116 C  CG2 . ILE A 1 575 ? 114.435 112.649 79.331  1.00 97.47 ? 563 ILE A CG2 1 
ATOM   4117 C  CD1 . ILE A 1 575 ? 111.516 113.370 78.894  1.00 97.47 ? 563 ILE A CD1 1 
ATOM   4118 N  N   . ARG A 1 576 ? 114.654 109.105 77.965  1.00 94.84 ? 564 ARG A N   1 
ATOM   4119 C  CA  . ARG A 1 576 ? 115.839 108.373 77.526  1.00 94.84 ? 564 ARG A CA  1 
ATOM   4120 C  C   . ARG A 1 576 ? 115.795 108.039 76.042  1.00 94.84 ? 564 ARG A C   1 
ATOM   4121 O  O   . ARG A 1 576 ? 116.803 108.150 75.351  1.00 94.84 ? 564 ARG A O   1 
ATOM   4122 C  CB  . ARG A 1 576 ? 116.027 107.092 78.341  1.00 94.84 ? 564 ARG A CB  1 
ATOM   4123 C  CG  . ARG A 1 576 ? 116.271 107.309 79.824  1.00 94.84 ? 564 ARG A CG  1 
ATOM   4124 C  CD  . ARG A 1 576 ? 117.461 108.217 80.073  1.00 94.84 ? 564 ARG A CD  1 
ATOM   4125 N  NE  . ARG A 1 576 ? 118.730 107.548 79.808  1.00 94.84 ? 564 ARG A NE  1 
ATOM   4126 C  CZ  . ARG A 1 576 ? 119.466 106.951 80.739  1.00 94.84 ? 564 ARG A CZ  1 
ATOM   4127 N  NH1 . ARG A 1 576 ? 119.061 106.941 82.002  1.00 94.84 ? 564 ARG A NH1 1 
ATOM   4128 N  NH2 . ARG A 1 576 ? 120.610 106.368 80.409  1.00 94.84 ? 564 ARG A NH2 1 
ATOM   4129 N  N   . LEU A 1 577 ? 114.634 107.633 75.548  1.00 96.07 ? 565 LEU A N   1 
ATOM   4130 C  CA  . LEU A 1 577 ? 114.517 107.271 74.143  1.00 96.07 ? 565 LEU A CA  1 
ATOM   4131 C  C   . LEU A 1 577 ? 114.784 108.477 73.267  1.00 96.07 ? 565 LEU A C   1 
ATOM   4132 O  O   . LEU A 1 577 ? 115.523 108.388 72.290  1.00 96.07 ? 565 LEU A O   1 
ATOM   4133 C  CB  . LEU A 1 577 ? 113.145 106.677 73.844  1.00 96.07 ? 565 LEU A CB  1 
ATOM   4134 C  CG  . LEU A 1 577 ? 112.934 105.269 74.391  1.00 96.07 ? 565 LEU A CG  1 
ATOM   4135 C  CD1 . LEU A 1 577 ? 111.476 104.856 74.286  1.00 96.07 ? 565 LEU A CD1 1 
ATOM   4136 C  CD2 . LEU A 1 577 ? 113.841 104.285 73.675  1.00 96.07 ? 565 LEU A CD2 1 
ATOM   4137 N  N   . CYS A 1 578 ? 114.226 109.620 73.642  1.00 95.59 ? 566 CYS A N   1 
ATOM   4138 C  CA  . CYS A 1 578 ? 114.437 110.843 72.877  1.00 95.59 ? 566 CYS A CA  1 
ATOM   4139 C  C   . CYS A 1 578 ? 115.887 111.304 72.895  1.00 95.59 ? 566 CYS A C   1 
ATOM   4140 O  O   . CYS A 1 578 ? 116.444 111.636 71.851  1.00 95.59 ? 566 CYS A O   1 
ATOM   4141 C  CB  . CYS A 1 578 ? 113.535 111.955 73.410  1.00 95.59 ? 566 CYS A CB  1 
ATOM   4142 S  SG  . CYS A 1 578 ? 111.768 111.684 73.150  1.00 95.59 ? 566 CYS A SG  1 
ATOM   4143 N  N   . GLN A 1 579 ? 116.507 111.327 74.069  1.00 93.20 ? 567 GLN A N   1 
ATOM   4144 C  CA  . GLN A 1 579 ? 117.875 111.829 74.178  1.00 93.20 ? 567 GLN A CA  1 
ATOM   4145 C  C   . GLN A 1 579 ? 118.889 111.021 73.390  1.00 93.20 ? 567 GLN A C   1 
ATOM   4146 O  O   . GLN A 1 579 ? 119.780 111.589 72.762  1.00 93.20 ? 567 GLN A O   1 
ATOM   4147 C  CB  . GLN A 1 579 ? 118.303 111.891 75.641  1.00 93.20 ? 567 GLN A CB  1 
ATOM   4148 C  CG  . GLN A 1 579 ? 117.704 113.044 76.422  1.00 93.20 ? 567 GLN A CG  1 
ATOM   4149 C  CD  . GLN A 1 579 ? 117.998 112.943 77.903  1.00 93.20 ? 567 GLN A CD  1 
ATOM   4150 O  OE1 . GLN A 1 579 ? 117.996 113.944 78.619  1.00 93.20 ? 567 GLN A OE1 1 
ATOM   4151 N  NE2 . GLN A 1 579 ? 118.262 111.728 78.371  1.00 93.20 ? 567 GLN A NE2 1 
ATOM   4152 N  N   . THR A 1 580 ? 118.761 109.700 73.407  1.00 92.37 ? 568 THR A N   1 
ATOM   4153 C  CA  . THR A 1 580 ? 119.689 108.846 72.674  1.00 92.37 ? 568 THR A CA  1 
ATOM   4154 C  C   . THR A 1 580 ? 119.505 109.015 71.178  1.00 92.37 ? 568 THR A C   1 
ATOM   4155 O  O   . THR A 1 580 ? 118.412 109.334 70.720  1.00 92.37 ? 568 THR A O   1 
ATOM   4156 C  CB  . THR A 1 580 ? 119.526 107.373 73.056  1.00 92.37 ? 568 THR A CB  1 
ATOM   4157 O  OG1 . THR A 1 580 ? 118.138 107.023 73.013  1.00 92.37 ? 568 THR A OG1 1 
ATOM   4158 C  CG2 . THR A 1 580 ? 120.054 107.144 74.455  1.00 92.37 ? 568 THR A CG2 1 
ATOM   4159 N  N   . GLU A 1 581 ? 120.565 108.803 70.409  1.00 88.82 ? 569 GLU A N   1 
ATOM   4160 C  CA  . GLU A 1 581 ? 120.485 109.022 68.968  1.00 88.82 ? 569 GLU A CA  1 
ATOM   4161 C  C   . GLU A 1 581 ? 120.558 107.734 68.175  1.00 88.82 ? 569 GLU A C   1 
ATOM   4162 O  O   . GLU A 1 581 ? 121.451 106.917 68.390  1.00 88.82 ? 569 GLU A O   1 
ATOM   4163 C  CB  . GLU A 1 581 ? 121.603 109.956 68.510  1.00 88.82 ? 569 GLU A CB  1 
ATOM   4164 C  CG  . GLU A 1 581 ? 121.528 111.354 69.101  1.00 88.82 ? 569 GLU A CG  1 
ATOM   4165 C  CD  . GLU A 1 581 ? 122.645 112.253 68.611  1.00 88.82 ? 569 GLU A CD  1 
ATOM   4166 O  OE1 . GLU A 1 581 ? 123.499 111.773 67.837  1.00 88.82 ? 569 GLU A OE1 1 
ATOM   4167 O  OE2 . GLU A 1 581 ? 122.670 113.439 69.000  1.00 88.82 ? 569 GLU A OE2 1 
ATOM   4168 N  N   . GLY A 1 582 ? 119.620 107.544 67.257  1.00 90.94 ? 570 GLY A N   1 
ATOM   4169 C  CA  . GLY A 1 582 ? 119.666 106.368 66.418  1.00 90.94 ? 570 GLY A CA  1 
ATOM   4170 C  C   . GLY A 1 582 ? 118.324 105.768 66.001  1.00 90.94 ? 570 GLY A C   1 
ATOM   4171 O  O   . GLY A 1 582 ? 117.285 106.354 66.298  1.00 90.94 ? 570 GLY A O   1 
ATOM   4172 N  N   . PRO A 1 583 ? 118.327 104.604 65.291  1.00 93.16 ? 571 PRO A N   1 
ATOM   4173 C  CA  . PRO A 1 583 ? 117.013 104.030 64.995  1.00 93.16 ? 571 PRO A CA  1 
ATOM   4174 C  C   . PRO A 1 583 ? 116.356 103.579 66.291  1.00 93.16 ? 571 PRO A C   1 
ATOM   4175 O  O   . PRO A 1 583 ? 117.066 103.210 67.223  1.00 93.16 ? 571 PRO A O   1 
ATOM   4176 C  CB  . PRO A 1 583 ? 117.353 102.819 64.126  1.00 93.16 ? 571 PRO A CB  1 
ATOM   4177 C  CG  . PRO A 1 583 ? 118.674 103.147 63.516  1.00 93.16 ? 571 PRO A CG  1 
ATOM   4178 C  CD  . PRO A 1 583 ? 119.412 103.928 64.562  1.00 93.16 ? 571 PRO A CD  1 
ATOM   4179 N  N   . PHE A 1 584 ? 115.028 103.602 66.352  1.00 92.51 ? 572 PHE A N   1 
ATOM   4180 C  CA  . PHE A 1 584 ? 114.321 103.244 67.580  1.00 92.51 ? 572 PHE A CA  1 
ATOM   4181 C  C   . PHE A 1 584 ? 114.854 101.976 68.221  1.00 92.51 ? 572 PHE A C   1 
ATOM   4182 O  O   . PHE A 1 584 ? 115.170 101.968 69.406  1.00 92.51 ? 572 PHE A O   1 
ATOM   4183 C  CB  . PHE A 1 584 ? 112.822 103.095 67.323  1.00 92.51 ? 572 PHE A CB  1 
ATOM   4184 C  CG  . PHE A 1 584 ? 112.024 102.799 68.559  1.00 92.51 ? 572 PHE A CG  1 
ATOM   4185 C  CD1 . PHE A 1 584 ? 111.862 103.763 69.538  1.00 92.51 ? 572 PHE A CD1 1 
ATOM   4186 C  CD2 . PHE A 1 584 ? 111.435 101.559 68.741  1.00 92.51 ? 572 PHE A CD2 1 
ATOM   4187 C  CE1 . PHE A 1 584 ? 111.129 103.497 70.678  1.00 92.51 ? 572 PHE A CE1 1 
ATOM   4188 C  CE2 . PHE A 1 584 ? 110.702 101.286 69.878  1.00 92.51 ? 572 PHE A CE2 1 
ATOM   4189 C  CZ  . PHE A 1 584 ? 110.547 102.257 70.848  1.00 92.51 ? 572 PHE A CZ  1 
ATOM   4190 N  N   . LEU A 1 585 ? 114.959 100.904 67.446  1.00 92.32 ? 573 LEU A N   1 
ATOM   4191 C  CA  . LEU A 1 585 ? 115.394 99.633  68.014  1.00 92.32 ? 573 LEU A CA  1 
ATOM   4192 C  C   . LEU A 1 585 ? 116.803 99.708  68.570  1.00 92.32 ? 573 LEU A C   1 
ATOM   4193 O  O   . LEU A 1 585 ? 117.073 99.182  69.642  1.00 92.32 ? 573 LEU A O   1 
ATOM   4194 C  CB  . LEU A 1 585 ? 115.293 98.520  66.979  1.00 92.32 ? 573 LEU A CB  1 
ATOM   4195 C  CG  . LEU A 1 585 ? 113.882 98.291  66.436  1.00 92.32 ? 573 LEU A CG  1 
ATOM   4196 C  CD1 . LEU A 1 585 ? 113.892 97.246  65.332  1.00 92.32 ? 573 LEU A CD1 1 
ATOM   4197 C  CD2 . LEU A 1 585 ? 112.936 97.887  67.557  1.00 92.32 ? 573 LEU A CD2 1 
ATOM   4198 N  N   . VAL A 1 586 ? 117.700 100.375 67.858  1.00 91.67 ? 574 VAL A N   1 
ATOM   4199 C  CA  . VAL A 1 586 ? 119.068 100.527 68.338  1.00 91.67 ? 574 VAL A CA  1 
ATOM   4200 C  C   . VAL A 1 586 ? 119.101 101.324 69.637  1.00 91.67 ? 574 VAL A C   1 
ATOM   4201 O  O   . VAL A 1 586 ? 119.827 100.972 70.566  1.00 91.67 ? 574 VAL A O   1 
ATOM   4202 C  CB  . VAL A 1 586 ? 119.961 101.189 67.270  1.00 91.67 ? 574 VAL A CB  1 
ATOM   4203 C  CG1 . VAL A 1 586 ? 121.375 101.398 67.789  1.00 91.67 ? 574 VAL A CG1 1 
ATOM   4204 C  CG2 . VAL A 1 586 ? 119.979 100.341 66.009  1.00 91.67 ? 574 VAL A CG2 1 
ATOM   4205 N  N   . ARG A 1 587 ? 118.301 102.381 69.718  1.00 91.86 ? 575 ARG A N   1 
ATOM   4206 C  CA  . ARG A 1 587 ? 118.240 103.167 70.942  1.00 91.86 ? 575 ARG A CA  1 
ATOM   4207 C  C   . ARG A 1 587 ? 117.807 102.283 72.087  1.00 91.86 ? 575 ARG A C   1 
ATOM   4208 O  O   . ARG A 1 587 ? 118.457 102.258 73.127  1.00 91.86 ? 575 ARG A O   1 
ATOM   4209 C  CB  . ARG A 1 587 ? 117.241 104.308 70.806  1.00 91.86 ? 575 ARG A CB  1 
ATOM   4210 C  CG  . ARG A 1 587 ? 117.639 105.402 69.837  1.00 91.86 ? 575 ARG A CG  1 
ATOM   4211 C  CD  . ARG A 1 587 ? 116.496 106.387 69.681  1.00 91.86 ? 575 ARG A CD  1 
ATOM   4212 N  NE  . ARG A 1 587 ? 116.893 107.577 68.939  1.00 91.86 ? 575 ARG A NE  1 
ATOM   4213 C  CZ  . ARG A 1 587 ? 116.079 108.590 68.668  1.00 91.86 ? 575 ARG A CZ  1 
ATOM   4214 N  NH1 . ARG A 1 587 ? 114.820 108.558 69.080  1.00 91.86 ? 575 ARG A NH1 1 
ATOM   4215 N  NH2 . ARG A 1 587 ? 116.524 109.637 67.989  1.00 91.86 ? 575 ARG A NH2 1 
ATOM   4216 N  N   . VAL A 1 588 ? 116.711 101.553 71.901  1.00 94.01 ? 576 VAL A N   1 
ATOM   4217 C  CA  . VAL A 1 588 ? 116.191 100.709 72.963  1.00 94.01 ? 576 VAL A CA  1 
ATOM   4218 C  C   . VAL A 1 588 ? 117.287 99.770  73.416  1.00 94.01 ? 576 VAL A C   1 
ATOM   4219 O  O   . VAL A 1 588 ? 117.547 99.654  74.605  1.00 94.01 ? 576 VAL A O   1 
ATOM   4220 C  CB  . VAL A 1 588 ? 114.970 99.892  72.499  1.00 94.01 ? 576 VAL A CB  1 
ATOM   4221 C  CG1 . VAL A 1 588 ? 114.553 98.889  73.562  1.00 94.01 ? 576 VAL A CG1 1 
ATOM   4222 C  CG2 . VAL A 1 588 ? 113.811 100.814 72.169  1.00 94.01 ? 576 VAL A CG2 1 
ATOM   4223 N  N   . LYS A 1 589 ? 117.951 99.121  72.470  1.00 91.82 ? 577 LYS A N   1 
ATOM   4224 C  CA  . LYS A 1 589 ? 118.989 98.151  72.814  1.00 91.82 ? 577 LYS A CA  1 
ATOM   4225 C  C   . LYS A 1 589 ? 120.094 98.741  73.674  1.00 91.82 ? 577 LYS A C   1 
ATOM   4226 O  O   . LYS A 1 589 ? 120.483 98.148  74.672  1.00 91.82 ? 577 LYS A O   1 
ATOM   4227 C  CB  . LYS A 1 589 ? 119.592 97.525  71.555  1.00 91.82 ? 577 LYS A CB  1 
ATOM   4228 C  CG  . LYS A 1 589 ? 118.636 96.619  70.799  1.00 91.82 ? 577 LYS A CG  1 
ATOM   4229 C  CD  . LYS A 1 589 ? 118.059 95.536  71.695  1.00 91.82 ? 577 LYS A CD  1 
ATOM   4230 C  CE  . LYS A 1 589 ? 119.108 94.506  72.085  1.00 91.82 ? 577 LYS A CE  1 
ATOM   4231 N  NZ  . LYS A 1 589 ? 119.639 93.785  70.897  1.00 91.82 ? 577 LYS A NZ  1 
ATOM   4232 N  N   . TYR A 1 590 ? 120.611 99.899  73.283  1.00 90.23 ? 578 TYR A N   1 
ATOM   4233 C  CA  . TYR A 1 590 ? 121.675 100.537 74.047  1.00 90.23 ? 578 TYR A CA  1 
ATOM   4234 C  C   . TYR A 1 590 ? 121.166 100.890 75.430  1.00 90.23 ? 578 TYR A C   1 
ATOM   4235 O  O   . TYR A 1 590 ? 121.853 100.680 76.428  1.00 90.23 ? 578 TYR A O   1 
ATOM   4236 C  CB  . TYR A 1 590 ? 122.161 101.787 73.308  1.00 90.23 ? 578 TYR A CB  1 
ATOM   4237 C  CG  . TYR A 1 590 ? 122.947 102.753 74.162  1.00 90.23 ? 578 TYR A CG  1 
ATOM   4238 C  CD1 . TYR A 1 590 ? 124.240 102.458 74.565  1.00 90.23 ? 578 TYR A CD1 1 
ATOM   4239 C  CD2 . TYR A 1 590 ? 122.397 103.965 74.557  1.00 90.23 ? 578 TYR A CD2 1 
ATOM   4240 C  CE1 . TYR A 1 590 ? 124.961 103.337 75.348  1.00 90.23 ? 578 TYR A CE1 1 
ATOM   4241 C  CE2 . TYR A 1 590 ? 123.109 104.849 75.339  1.00 90.23 ? 578 TYR A CE2 1 
ATOM   4242 C  CZ  . TYR A 1 590 ? 124.391 104.531 75.730  1.00 90.23 ? 578 TYR A CZ  1 
ATOM   4243 O  OH  . TYR A 1 590 ? 125.108 105.410 76.507  1.00 90.23 ? 578 TYR A OH  1 
ATOM   4244 N  N   . LEU A 1 591 ? 119.953 101.416 75.500  1.00 93.07 ? 579 LEU A N   1 
ATOM   4245 C  CA  . LEU A 1 591 ? 119.353 101.733 76.784  1.00 93.07 ? 579 LEU A CA  1 
ATOM   4246 C  C   . LEU A 1 591 ? 119.114 100.489 77.623  1.00 93.07 ? 579 LEU A C   1 
ATOM   4247 O  O   . LEU A 1 591 ? 119.152 100.558 78.826  1.00 93.07 ? 579 LEU A O   1 
ATOM   4248 C  CB  . LEU A 1 591 ? 118.090 102.561 76.599  1.00 93.07 ? 579 LEU A CB  1 
ATOM   4249 C  CG  . LEU A 1 591 ? 118.409 103.986 76.164  1.00 93.07 ? 579 LEU A CG  1 
ATOM   4250 C  CD1 . LEU A 1 591 ? 117.193 104.670 75.574  1.00 93.07 ? 579 LEU A CD1 1 
ATOM   4251 C  CD2 . LEU A 1 591 ? 118.997 104.783 77.315  1.00 93.07 ? 579 LEU A CD2 1 
ATOM   4252 N  N   . LEU A 1 592 ? 118.748 99.375  77.010  1.00 94.17 ? 580 LEU A N   1 
ATOM   4253 C  CA  . LEU A 1 592 ? 118.616 98.130  77.766  1.00 94.17 ? 580 LEU A CA  1 
ATOM   4254 C  C   . LEU A 1 592 ? 119.930 97.595  78.335  1.00 94.17 ? 580 LEU A C   1 
ATOM   4255 O  O   . LEU A 1 592 ? 119.955 97.097  79.456  1.00 94.17 ? 580 LEU A O   1 
ATOM   4256 C  CB  . LEU A 1 592 ? 117.915 97.048  76.941  1.00 94.17 ? 580 LEU A CB  1 
ATOM   4257 C  CG  . LEU A 1 592 ? 116.411 97.233  76.741  1.00 94.17 ? 580 LEU A CG  1 
ATOM   4258 C  CD1 . LEU A 1 592 ? 115.815 96.029  76.035  1.00 94.17 ? 580 LEU A CD1 1 
ATOM   4259 C  CD2 . LEU A 1 592 ? 115.719 97.471  78.071  1.00 94.17 ? 580 LEU A CD2 1 
ATOM   4260 N  N   . THR A 1 593 ? 121.019 97.678  77.579  1.00 90.02 ? 581 THR A N   1 
ATOM   4261 C  CA  . THR A 1 593 ? 122.291 97.087  78.024  1.00 90.02 ? 581 THR A CA  1 
ATOM   4262 C  C   . THR A 1 593 ? 122.923 97.695  79.268  1.00 90.02 ? 581 THR A C   1 
ATOM   4263 O  O   . THR A 1 593 ? 123.021 98.910  79.378  1.00 90.02 ? 581 THR A O   1 
ATOM   4264 C  CB  . THR A 1 593 ? 123.338 97.100  76.895  1.00 90.02 ? 581 THR A CB  1 
ATOM   4265 O  OG1 . THR A 1 593 ? 123.475 98.428  76.380  1.00 90.02 ? 581 THR A OG1 1 
ATOM   4266 C  CG2 . THR A 1 593 ? 122.921 96.166  75.776  1.00 90.02 ? 581 THR A CG2 1 
ATOM   4267 N  N   . PRO A 1 594 ? 123.405 96.844  80.186  1.00 87.27 ? 582 PRO A N   1 
ATOM   4268 C  CA  . PRO A 1 594 ? 124.004 97.319  81.441  1.00 87.27 ? 582 PRO A CA  1 
ATOM   4269 C  C   . PRO A 1 594 ? 125.323 98.064  81.297  1.00 87.27 ? 582 PRO A C   1 
ATOM   4270 O  O   . PRO A 1 594 ? 126.198 97.630  80.546  1.00 87.27 ? 582 PRO A O   1 
ATOM   4271 C  CB  . PRO A 1 594 ? 124.245 96.021  82.216  1.00 87.27 ? 582 PRO A CB  1 
ATOM   4272 C  CG  . PRO A 1 594 ? 123.320 95.025  81.615  1.00 87.27 ? 582 PRO A CG  1 
ATOM   4273 C  CD  . PRO A 1 594 ? 123.263 95.380  80.165  1.00 87.27 ? 582 PRO A CD  1 
ATOM   4274 N  N   . ARG A 1 595 ? 125.477 99.163  82.026  1.00 77.75 ? 583 ARG A N   1 
ATOM   4275 C  CA  . ARG A 1 595 ? 126.717 99.934  81.975  1.00 77.75 ? 583 ARG A CA  1 
ATOM   4276 C  C   . ARG A 1 595 ? 127.758 99.501  83.003  1.00 77.75 ? 583 ARG A C   1 
ATOM   4277 O  O   . ARG A 1 595 ? 127.886 100.149 84.046  1.00 77.75 ? 583 ARG A O   1 
ATOM   4278 C  CB  . ARG A 1 595 ? 126.417 101.421 82.176  1.00 77.75 ? 583 ARG A CB  1 
ATOM   4279 C  CG  . ARG A 1 595 ? 125.294 101.962 81.307  1.00 77.75 ? 583 ARG A CG  1 
ATOM   4280 C  CD  . ARG A 1 595 ? 124.987 103.397 81.690  1.00 77.75 ? 583 ARG A CD  1 
ATOM   4281 N  NE  . ARG A 1 595 ? 125.110 103.587 83.132  1.00 77.75 ? 583 ARG A NE  1 
ATOM   4282 C  CZ  . ARG A 1 595 ? 124.977 104.755 83.753  1.00 77.75 ? 583 ARG A CZ  1 
ATOM   4283 N  NH1 . ARG A 1 595 ? 124.712 105.857 83.064  1.00 77.75 ? 583 ARG A NH1 1 
ATOM   4284 N  NH2 . ARG A 1 595 ? 125.114 104.823 85.072  1.00 77.75 ? 583 ARG A NH2 1 
ATOM   4285 N  N   . GLU A 1 596 ? 128.491 98.425  82.722  1.00 67.90 ? 584 GLU A N   1 
ATOM   4286 C  CA  . GLU A 1 596 ? 129.516 97.906  83.649  1.00 67.90 ? 584 GLU A CA  1 
ATOM   4287 C  C   . GLU A 1 596 ? 129.111 97.870  85.127  1.00 67.90 ? 584 GLU A C   1 
ATOM   4288 O  O   . GLU A 1 596 ? 129.736 98.535  85.950  1.00 67.90 ? 584 GLU A O   1 
ATOM   4289 C  CB  . GLU A 1 596 ? 130.843 98.663  83.483  1.00 67.90 ? 584 GLU A CB  1 
ATOM   4290 C  CG  . GLU A 1 596 ? 131.502 98.499  82.121  1.00 67.90 ? 584 GLU A CG  1 
ATOM   4291 C  CD  . GLU A 1 596 ? 131.033 99.527  81.108  1.00 67.90 ? 584 GLU A CD  1 
ATOM   4292 O  OE1 . GLU A 1 596 ? 130.535 100.595 81.523  1.00 67.90 ? 584 GLU A OE1 1 
ATOM   4293 O  OE2 . GLU A 1 596 ? 131.170 99.270  79.894  1.00 67.90 ? 584 GLU A OE2 1 
ATOM   4294 N  N   . PRO A 1 597 ? 128.075 97.058  85.495  1.00 59.03 ? 585 PRO A N   1 
ATOM   4295 C  CA  . PRO A 1 597 ? 127.684 97.125  86.911  1.00 59.03 ? 585 PRO A CA  1 
ATOM   4296 C  C   . PRO A 1 597 ? 128.618 96.375  87.847  1.00 59.03 ? 585 PRO A C   1 
ATOM   4297 O  O   . PRO A 1 597 ? 128.577 96.622  89.052  1.00 59.03 ? 585 PRO A O   1 
ATOM   4298 C  CB  . PRO A 1 597 ? 126.299 96.461  86.931  1.00 59.03 ? 585 PRO A CB  1 
ATOM   4299 C  CG  . PRO A 1 597 ? 125.930 96.203  85.511  1.00 59.03 ? 585 PRO A CG  1 
ATOM   4300 C  CD  . PRO A 1 597 ? 127.227 96.073  84.788  1.00 59.03 ? 585 PRO A CD  1 
ATOM   4301 N  N   . ASN A 1 598 ? 129.452 95.489  87.314  1.00 57.47 ? 586 ASN A N   1 
ATOM   4302 C  CA  . ASN A 1 598 ? 130.333 94.683  88.152  1.00 57.47 ? 586 ASN A CA  1 
ATOM   4303 C  C   . ASN A 1 598 ? 131.280 95.592  88.897  1.00 57.47 ? 586 ASN A C   1 
ATOM   4304 O  O   . ASN A 1 598 ? 131.540 95.372  90.081  1.00 57.47 ? 586 ASN A O   1 
ATOM   4305 C  CB  . ASN A 1 598 ? 131.138 93.702  87.299  1.00 57.47 ? 586 ASN A CB  1 
ATOM   4306 C  CG  . ASN A 1 598 ? 130.266 92.856  86.388  1.00 57.47 ? 586 ASN A CG  1 
ATOM   4307 O  OD1 . ASN A 1 598 ? 129.043 92.992  86.365  1.00 57.47 ? 586 ASN A OD1 1 
ATOM   4308 N  ND2 . ASN A 1 598 ? 130.899 91.973  85.627  1.00 57.47 ? 586 ASN A ND2 1 
ATOM   4309 N  N   . ARG A 1 599 ? 131.793 96.611  88.209  1.00 56.94 ? 587 ARG A N   1 
ATOM   4310 C  CA  . ARG A 1 599 ? 132.694 97.571  88.834  1.00 56.94 ? 587 ARG A CA  1 
ATOM   4311 C  C   . ARG A 1 599 ? 133.785 96.844  89.612  1.00 56.94 ? 587 ARG A C   1 
ATOM   4312 O  O   . ARG A 1 599 ? 134.016 97.111  90.791  1.00 56.94 ? 587 ARG A O   1 
ATOM   4313 C  CB  . ARG A 1 599 ? 131.896 98.521  89.734  1.00 56.94 ? 587 ARG A CB  1 
ATOM   4314 C  CG  . ARG A 1 599 ? 132.606 99.799  90.156  1.00 56.94 ? 587 ARG A CG  1 
ATOM   4315 C  CD  . ARG A 1 599 ? 132.228 100.184 91.580  1.00 56.94 ? 587 ARG A CD  1 
ATOM   4316 N  NE  . ARG A 1 599 ? 132.815 99.285  92.575  1.00 56.94 ? 587 ARG A NE  1 
ATOM   4317 C  CZ  . ARG A 1 599 ? 132.174 98.276  93.161  1.00 56.94 ? 587 ARG A CZ  1 
ATOM   4318 N  NH1 . ARG A 1 599 ? 132.802 97.518  94.048  1.00 56.94 ? 587 ARG A NH1 1 
ATOM   4319 N  NH2 . ARG A 1 599 ? 130.907 98.025  92.867  1.00 56.94 ? 587 ARG A NH2 1 
ATOM   4320 N  N   . TRP A 1 600 ? 134.455 95.905  88.954  1.00 50.50 ? 588 TRP A N   1 
ATOM   4321 C  CA  . TRP A 1 600 ? 135.531 95.173  89.619  1.00 50.50 ? 588 TRP A CA  1 
ATOM   4322 C  C   . TRP A 1 600 ? 136.820 95.980  89.701  1.00 50.50 ? 588 TRP A C   1 
ATOM   4323 O  O   . TRP A 1 600 ? 137.294 96.297  90.791  1.00 50.50 ? 588 TRP A O   1 
ATOM   4324 C  CB  . TRP A 1 600 ? 135.781 93.832  88.926  1.00 50.50 ? 588 TRP A CB  1 
ATOM   4325 C  CG  . TRP A 1 600 ? 134.713 92.829  89.211  1.00 50.50 ? 588 TRP A CG  1 
ATOM   4326 C  CD1 . TRP A 1 600 ? 133.969 92.729  90.350  1.00 50.50 ? 588 TRP A CD1 1 
ATOM   4327 C  CD2 . TRP A 1 600 ? 134.274 91.771  88.352  1.00 50.50 ? 588 TRP A CD2 1 
ATOM   4328 N  NE1 . TRP A 1 600 ? 133.089 91.681  90.250  1.00 50.50 ? 588 TRP A NE1 1 
ATOM   4329 C  CE2 . TRP A 1 600 ? 133.257 91.075  89.034  1.00 50.50 ? 588 TRP A CE2 1 
ATOM   4330 C  CE3 . TRP A 1 600 ? 134.639 91.348  87.071  1.00 50.50 ? 588 TRP A CE3 1 
ATOM   4331 C  CZ2 . TRP A 1 600 ? 132.601 89.980  88.479  1.00 50.50 ? 588 TRP A CZ2 1 
ATOM   4332 C  CZ3 . TRP A 1 600 ? 133.987 90.260  86.522  1.00 50.50 ? 588 TRP A CZ3 1 
ATOM   4333 C  CH2 . TRP A 1 600 ? 132.980 89.589  87.226  1.00 50.50 ? 588 TRP A CH2 1 
HETATM 4334 C  C1  . TAU B 2 .   ? 97.000  100.972 101.204 1.00 30.00 ? 701 TAU A C1  1 
HETATM 4335 C  C2  . TAU B 2 .   ? 96.786  100.278 102.547 1.00 30.00 ? 701 TAU A C2  1 
HETATM 4336 N  N1  . TAU B 2 .   ? 97.057  99.998  100.132 1.00 30.00 ? 701 TAU A N1  1 
HETATM 4337 S  S   . TAU B 2 .   ? 96.527  101.470 103.896 1.00 30.00 ? 701 TAU A S   1 
HETATM 4338 O  O1  . TAU B 2 .   ? 97.041  102.833 103.644 1.00 30.00 ? 701 TAU A O1  1 
HETATM 4339 O  O2  . TAU B 2 .   ? 97.516  101.286 105.010 1.00 30.00 ? 701 TAU A O2  1 
HETATM 4340 O  O3  . TAU B 2 .   ? 95.086  101.524 104.340 1.00 30.00 ? 701 TAU A O3  1 
HETATM 4341 C  C1  . TAU C 2 .   ? 113.910 97.677  106.686 1.00 30.00 ? 702 TAU A C1  1 
HETATM 4342 C  C2  . TAU C 2 .   ? 113.935 97.053  108.063 1.00 30.00 ? 702 TAU A C2  1 
HETATM 4343 N  N1  . TAU C 2 .   ? 114.530 98.961  106.848 1.00 30.00 ? 702 TAU A N1  1 
HETATM 4344 S  S   . TAU C 2 .   ? 114.120 95.267  107.932 1.00 30.00 ? 702 TAU A S   1 
HETATM 4345 O  O1  . TAU C 2 .   ? 115.535 94.807  108.207 1.00 30.00 ? 702 TAU A O1  1 
HETATM 4346 O  O2  . TAU C 2 .   ? 113.382 94.642  109.073 1.00 30.00 ? 702 TAU A O2  1 
HETATM 4347 O  O3  . TAU C 2 .   ? 113.664 94.745  106.606 1.00 30.00 ? 702 TAU A O3  1 
HETATM 4348 C  C1  . TAU D 2 .   ? 108.404 102.191 104.993 1.00 30.00 ? 703 TAU A C1  1 
HETATM 4349 C  C2  . TAU D 2 .   ? 108.119 103.292 103.990 1.00 30.00 ? 703 TAU A C2  1 
HETATM 4350 N  N1  . TAU D 2 .   ? 108.939 102.804 106.189 1.00 30.00 ? 703 TAU A N1  1 
HETATM 4351 S  S   . TAU D 2 .   ? 107.210 102.692 102.548 1.00 30.00 ? 703 TAU A S   1 
HETATM 4352 O  O1  . TAU D 2 .   ? 108.021 102.799 101.340 1.00 30.00 ? 703 TAU A O1  1 
HETATM 4353 O  O2  . TAU D 2 .   ? 106.949 101.221 102.545 1.00 30.00 ? 703 TAU A O2  1 
HETATM 4354 O  O3  . TAU D 2 .   ? 106.024 103.539 102.189 1.00 30.00 ? 703 TAU A O3  1 
HETATM 4355 C  C1  . TAU E 2 .   ? 109.360 99.125  110.536 1.00 30.00 ? 704 TAU A C1  1 
HETATM 4356 C  C2  . TAU E 2 .   ? 108.168 99.937  110.058 1.00 30.00 ? 704 TAU A C2  1 
HETATM 4357 N  N1  . TAU E 2 .   ? 108.894 97.970  111.277 1.00 30.00 ? 704 TAU A N1  1 
HETATM 4358 S  S   . TAU E 2 .   ? 108.668 101.505 109.298 1.00 30.00 ? 704 TAU A S   1 
HETATM 4359 O  O1  . TAU E 2 .   ? 109.015 101.395 107.844 1.00 30.00 ? 704 TAU A O1  1 
HETATM 4360 O  O2  . TAU E 2 .   ? 109.982 102.012 109.818 1.00 30.00 ? 704 TAU A O2  1 
HETATM 4361 O  O3  . TAU E 2 .   ? 107.597 102.537 109.474 1.00 30.00 ? 704 TAU A O3  1 
HETATM 4362 NA NA  . NA  F 3 .   ? 109.556 103.219 112.424 1.00 30.00 ? 705 NA  A NA  1 
HETATM 4363 CL CL  . CL  G 4 .   ? 105.281 94.425  108.716 1.00 30.00 ? 706 CL  A CL  1 
HETATM 4364 C  C1  . CLR H 5 .   ? 87.763  105.285 90.401  1.00 20.00 ? 707 CLR A C1  1 
HETATM 4365 C  C2  . CLR H 5 .   ? 87.215  106.120 91.551  1.00 20.00 ? 707 CLR A C2  1 
HETATM 4366 C  C3  . CLR H 5 .   ? 86.242  107.184 91.063  1.00 20.00 ? 707 CLR A C3  1 
HETATM 4367 C  C4  . CLR H 5 .   ? 86.935  108.098 90.059  1.00 20.00 ? 707 CLR A C4  1 
HETATM 4368 C  C5  . CLR H 5 .   ? 88.330  107.600 89.761  1.00 20.00 ? 707 CLR A C5  1 
HETATM 4369 C  C6  . CLR H 5 .   ? 89.343  108.483 89.812  1.00 20.00 ? 707 CLR A C6  1 
HETATM 4370 C  C7  . CLR H 5 .   ? 90.756  108.159 89.396  1.00 20.00 ? 707 CLR A C7  1 
HETATM 4371 C  C8  . CLR H 5 .   ? 90.807  106.821 88.678  1.00 20.00 ? 707 CLR A C8  1 
HETATM 4372 C  C9  . CLR H 5 .   ? 90.003  105.779 89.441  1.00 20.00 ? 707 CLR A C9  1 
HETATM 4373 C  C10 . CLR H 5 .   ? 88.529  106.143 89.405  1.00 20.00 ? 707 CLR A C10 1 
HETATM 4374 C  C11 . CLR H 5 .   ? 90.215  104.372 88.879  1.00 20.00 ? 707 CLR A C11 1 
HETATM 4375 C  C12 . CLR H 5 .   ? 91.684  103.985 88.704  1.00 20.00 ? 707 CLR A C12 1 
HETATM 4376 C  C13 . CLR H 5 .   ? 92.391  105.032 87.865  1.00 20.00 ? 707 CLR A C13 1 
HETATM 4377 C  C14 . CLR H 5 .   ? 92.248  106.362 88.568  1.00 20.00 ? 707 CLR A C14 1 
HETATM 4378 C  C15 . CLR H 5 .   ? 93.215  107.286 87.848  1.00 20.00 ? 707 CLR A C15 1 
HETATM 4379 C  C16 . CLR H 5 .   ? 94.390  106.361 87.537  1.00 20.00 ? 707 CLR A C16 1 
HETATM 4380 C  C17 . CLR H 5 .   ? 93.902  104.928 87.746  1.00 20.00 ? 707 CLR A C17 1 
HETATM 4381 C  C18 . CLR H 5 .   ? 91.789  105.081 86.463  1.00 20.00 ? 707 CLR A C18 1 
HETATM 4382 C  C19 . CLR H 5 .   ? 87.991  105.897 87.998  1.00 20.00 ? 707 CLR A C19 1 
HETATM 4383 C  C20 . CLR H 5 .   ? 94.421  103.996 86.661  1.00 20.00 ? 707 CLR A C20 1 
HETATM 4384 C  C21 . CLR H 5 .   ? 94.972  102.710 87.257  1.00 20.00 ? 707 CLR A C21 1 
HETATM 4385 C  C22 . CLR H 5 .   ? 95.481  104.703 85.829  1.00 20.00 ? 707 CLR A C22 1 
HETATM 4386 C  C23 . CLR H 5 .   ? 96.685  103.809 85.566  1.00 20.00 ? 707 CLR A C23 1 
HETATM 4387 C  C24 . CLR H 5 .   ? 97.547  104.426 84.472  1.00 20.00 ? 707 CLR A C24 1 
HETATM 4388 C  C25 . CLR H 5 .   ? 98.842  103.650 84.283  1.00 20.00 ? 707 CLR A C25 1 
HETATM 4389 C  C26 . CLR H 5 .   ? 99.932  104.180 85.204  1.00 20.00 ? 707 CLR A C26 1 
HETATM 4390 C  C27 . CLR H 5 .   ? 98.607  102.163 84.512  1.00 20.00 ? 707 CLR A C27 1 
HETATM 4391 O  O1  . CLR H 5 .   ? 85.134  106.539 90.426  1.00 20.00 ? 707 CLR A O1  1 
HETATM 4392 C  C1  . CLR I 5 .   ? 105.289 114.423 87.159  1.00 20.00 ? 708 CLR A C1  1 
HETATM 4393 C  C2  . CLR I 5 .   ? 104.168 115.343 87.638  1.00 20.00 ? 708 CLR A C2  1 
HETATM 4394 C  C3  . CLR I 5 .   ? 104.052 115.430 89.160  1.00 20.00 ? 708 CLR A C3  1 
HETATM 4395 C  C4  . CLR I 5 .   ? 105.115 114.568 89.834  1.00 20.00 ? 708 CLR A C4  1 
HETATM 4396 C  C5  . CLR I 5 .   ? 106.483 114.763 89.231  1.00 20.00 ? 708 CLR A C5  1 
HETATM 4397 C  C6  . CLR I 5 .   ? 107.563 114.800 90.016  1.00 20.00 ? 708 CLR A C6  1 
HETATM 4398 C  C7  . CLR I 5 .   ? 108.771 113.992 89.617  1.00 20.00 ? 708 CLR A C7  1 
HETATM 4399 C  C8  . CLR I 5 .   ? 109.012 114.216 88.133  1.00 20.00 ? 708 CLR A C8  1 
HETATM 4400 C  C9  . CLR I 5 .   ? 107.759 113.950 87.305  1.00 20.00 ? 708 CLR A C9  1 
HETATM 4401 C  C10 . CLR I 5 .   ? 106.625 114.858 87.739  1.00 20.00 ? 708 CLR A C10 1 
HETATM 4402 C  C11 . CLR I 5 .   ? 108.058 114.146 85.819  1.00 20.00 ? 708 CLR A C11 1 
HETATM 4403 C  C12 . CLR I 5 .   ? 109.258 113.332 85.335  1.00 20.00 ? 708 CLR A C12 1 
HETATM 4404 C  C13 . CLR I 5 .   ? 110.462 113.692 86.183  1.00 20.00 ? 708 CLR A C13 1 
HETATM 4405 C  C14 . CLR I 5 .   ? 110.121 113.324 87.610  1.00 20.00 ? 708 CLR A C14 1 
HETATM 4406 C  C15 . CLR I 5 .   ? 111.447 113.358 88.346  1.00 20.00 ? 708 CLR A C15 1 
HETATM 4407 C  C16 . CLR I 5 .   ? 112.435 112.856 87.296  1.00 20.00 ? 708 CLR A C16 1 
HETATM 4408 C  C17 . CLR I 5 .   ? 111.745 112.922 85.937  1.00 20.00 ? 708 CLR A C17 1 
HETATM 4409 C  C18 . CLR I 5 .   ? 110.768 115.184 86.065  1.00 20.00 ? 708 CLR A C18 1 
HETATM 4410 C  C19 . CLR I 5 .   ? 106.960 116.285 87.309  1.00 20.00 ? 708 CLR A C19 1 
HETATM 4411 C  C20 . CLR I 5 .   ? 112.663 113.533 84.887  1.00 20.00 ? 708 CLR A C20 1 
HETATM 4412 C  C21 . CLR I 5 .   ? 112.345 113.053 83.476  1.00 20.00 ? 708 CLR A C21 1 
HETATM 4413 C  C22 . CLR I 5 .   ? 114.113 113.235 85.234  1.00 20.00 ? 708 CLR A C22 1 
HETATM 4414 C  C23 . CLR I 5 .   ? 114.960 113.194 83.971  1.00 20.00 ? 708 CLR A C23 1 
HETATM 4415 C  C24 . CLR I 5 .   ? 116.420 112.949 84.320  1.00 20.00 ? 708 CLR A C24 1 
HETATM 4416 C  C25 . CLR I 5 .   ? 117.225 112.571 83.086  1.00 20.00 ? 708 CLR A C25 1 
HETATM 4417 C  C26 . CLR I 5 .   ? 116.652 111.320 82.434  1.00 20.00 ? 708 CLR A C26 1 
HETATM 4418 C  C27 . CLR I 5 .   ? 117.284 113.732 82.102  1.00 20.00 ? 708 CLR A C27 1 
HETATM 4419 O  O1  . CLR I 5 .   ? 104.217 116.794 89.565  1.00 20.00 ? 708 CLR A O1  1 
HETATM 4420 C  C1  . CLR J 5 .   ? 89.567  120.077 101.092 1.00 20.00 ? 709 CLR A C1  1 
HETATM 4421 C  C2  . CLR J 5 .   ? 88.361  120.895 100.638 1.00 20.00 ? 709 CLR A C2  1 
HETATM 4422 C  C3  . CLR J 5 .   ? 88.506  122.368 100.999 1.00 20.00 ? 709 CLR A C3  1 
HETATM 4423 C  C4  . CLR J 5 .   ? 89.812  122.892 100.412 1.00 20.00 ? 709 CLR A C4  1 
HETATM 4424 C  C5  . CLR J 5 .   ? 90.924  121.963 100.832 1.00 20.00 ? 709 CLR A C5  1 
HETATM 4425 C  C6  . CLR J 5 .   ? 91.908  122.437 101.603 1.00 20.00 ? 709 CLR A C6  1 
HETATM 4426 C  C7  . CLR J 5 .   ? 93.189  121.673 101.765 1.00 20.00 ? 709 CLR A C7  1 
HETATM 4427 C  C8  . CLR J 5 .   ? 93.251  120.626 100.667 1.00 20.00 ? 709 CLR A C8  1 
HETATM 4428 C  C9  . CLR J 5 .   ? 92.049  119.668 100.752 1.00 20.00 ? 709 CLR A C9  1 
HETATM 4429 C  C10 . CLR J 5 .   ? 90.833  120.527 100.378 1.00 20.00 ? 709 CLR A C10 1 
HETATM 4430 C  C11 . CLR J 5 .   ? 92.343  118.390 99.976  1.00 20.00 ? 709 CLR A C11 1 
HETATM 4431 C  C12 . CLR J 5 .   ? 93.712  117.795 100.302 1.00 20.00 ? 709 CLR A C12 1 
HETATM 4432 C  C13 . CLR J 5 .   ? 94.757  118.792 99.844  1.00 20.00 ? 709 CLR A C13 1 
HETATM 4433 C  C14 . CLR J 5 .   ? 94.612  119.963 100.769 1.00 20.00 ? 709 CLR A C14 1 
HETATM 4434 C  C15 . CLR J 5 .   ? 95.798  120.836 100.399 1.00 20.00 ? 709 CLR A C15 1 
HETATM 4435 C  C16 . CLR J 5 .   ? 96.907  119.823 100.111 1.00 20.00 ? 709 CLR A C16 1 
HETATM 4436 C  C17 . CLR J 5 .   ? 96.232  118.460 99.997  1.00 20.00 ? 709 CLR A C17 1 
HETATM 4437 C  C18 . CLR J 5 .   ? 94.529  119.234 98.400  1.00 20.00 ? 709 CLR A C18 1 
HETATM 4438 C  C19 . CLR J 5 .   ? 90.717  120.612 98.859  1.00 20.00 ? 709 CLR A C19 1 
HETATM 4439 C  C20 . CLR J 5 .   ? 96.822  117.655 98.853  1.00 20.00 ? 709 CLR A C20 1 
HETATM 4440 C  C21 . CLR J 5 .   ? 97.001  116.197 99.245  1.00 20.00 ? 709 CLR A C21 1 
HETATM 4441 C  C22 . CLR J 5 .   ? 98.147  118.229 98.368  1.00 20.00 ? 709 CLR A C22 1 
HETATM 4442 C  C23 . CLR J 5 .   ? 98.697  117.336 97.263  1.00 20.00 ? 709 CLR A C23 1 
HETATM 4443 C  C24 . CLR J 5 .   ? 99.877  117.968 96.536  1.00 20.00 ? 709 CLR A C24 1 
HETATM 4444 C  C25 . CLR J 5 .   ? 101.119 118.040 97.414  1.00 20.00 ? 709 CLR A C25 1 
HETATM 4445 C  C26 . CLR J 5 .   ? 101.547 116.660 97.893  1.00 20.00 ? 709 CLR A C26 1 
HETATM 4446 C  C27 . CLR J 5 .   ? 102.259 118.726 96.672  1.00 20.00 ? 709 CLR A C27 1 
HETATM 4447 O  O1  . CLR J 5 .   ? 87.393  123.106 100.485 1.00 20.00 ? 709 CLR A O1  1 
HETATM 4448 C  C1  . CLR K 5 .   ? 92.340  125.775 105.224 1.00 20.00 ? 710 CLR A C1  1 
HETATM 4449 C  C2  . CLR K 5 .   ? 91.131  126.693 105.333 1.00 20.00 ? 710 CLR A C2  1 
HETATM 4450 C  C3  . CLR K 5 .   ? 91.105  127.357 106.704 1.00 20.00 ? 710 CLR A C3  1 
HETATM 4451 C  C4  . CLR K 5 .   ? 92.319  128.270 106.813 1.00 20.00 ? 710 CLR A C4  1 
HETATM 4452 C  C5  . CLR K 5 .   ? 93.568  127.461 106.557 1.00 20.00 ? 710 CLR A C5  1 
HETATM 4453 C  C6  . CLR K 5 .   ? 94.591  127.564 107.424 1.00 20.00 ? 710 CLR A C6  1 
HETATM 4454 C  C7  . CLR K 5 .   ? 95.950  126.944 107.198 1.00 20.00 ? 710 CLR A C7  1 
HETATM 4455 C  C8  . CLR K 5 .   ? 96.062  126.429 105.773 1.00 20.00 ? 710 CLR A C8  1 
HETATM 4456 C  C9  . CLR K 5 .   ? 94.813  125.632 105.425 1.00 20.00 ? 710 CLR A C9  1 
HETATM 4457 C  C10 . CLR K 5 .   ? 93.628  126.577 105.333 1.00 20.00 ? 710 CLR A C10 1 
HETATM 4458 C  C11 . CLR K 5 .   ? 94.957  124.852 104.116 1.00 20.00 ? 710 CLR A C11 1 
HETATM 4459 C  C12 . CLR K 5 .   ? 96.266  124.072 104.002 1.00 20.00 ? 710 CLR A C12 1 
HETATM 4460 C  C13 . CLR K 5 .   ? 97.418  125.037 104.203 1.00 20.00 ? 710 CLR A C13 1 
HETATM 4461 C  C14 . CLR K 5 .   ? 97.300  125.563 105.614 1.00 20.00 ? 710 CLR A C14 1 
HETATM 4462 C  C15 . CLR K 5 .   ? 98.646  126.214 105.886 1.00 20.00 ? 710 CLR A C15 1 
HETATM 4463 C  C16 . CLR K 5 .   ? 99.634  125.320 105.134 1.00 20.00 ? 710 CLR A C16 1 
HETATM 4464 C  C17 . CLR K 5 .   ? 98.823  124.465 104.162 1.00 20.00 ? 710 CLR A C17 1 
HETATM 4465 C  C18 . CLR K 5 .   ? 97.361  126.177 103.186 1.00 20.00 ? 710 CLR A C18 1 
HETATM 4466 C  C19 . CLR K 5 .   ? 93.780  127.461 104.099 1.00 20.00 ? 710 CLR A C19 1 
HETATM 4467 C  C20 . CLR K 5 .   ? 99.425  124.456 102.763 1.00 20.00 ? 710 CLR A C20 1 
HETATM 4468 C  C21 . CLR K 5 .   ? 99.267  123.099 102.084 1.00 20.00 ? 710 CLR A C21 1 
HETATM 4469 C  C22 . CLR K 5 .   ? 100.891 124.863 102.795 1.00 20.00 ? 710 CLR A C22 1 
HETATM 4470 C  C23 . CLR K 5 .   ? 101.502 124.721 101.409 1.00 20.00 ? 710 CLR A C23 1 
HETATM 4471 C  C24 . CLR K 5 .   ? 102.999 124.988 101.449 1.00 20.00 ? 710 CLR A C24 1 
HETATM 4472 C  C25 . CLR K 5 .   ? 103.617 124.724 100.085 1.00 20.00 ? 710 CLR A C25 1 
HETATM 4473 C  C26 . CLR K 5 .   ? 105.127 124.917 100.125 1.00 20.00 ? 710 CLR A C26 1 
HETATM 4474 C  C27 . CLR K 5 .   ? 103.251 123.329 99.594  1.00 20.00 ? 710 CLR A C27 1 
HETATM 4475 O  O1  . CLR K 5 .   ? 89.909  128.128 106.847 1.00 20.00 ? 710 CLR A O1  1 
HETATM 4476 C  C1  . CLR L 5 .   ? 98.229  122.608 126.290 1.00 20.00 ? 711 CLR A C1  1 
HETATM 4477 C  C2  . CLR L 5 .   ? 97.445  122.092 127.492 1.00 20.00 ? 711 CLR A C2  1 
HETATM 4478 C  C3  . CLR L 5 .   ? 97.035  120.634 127.316 1.00 20.00 ? 711 CLR A C3  1 
HETATM 4479 C  C4  . CLR L 5 .   ? 98.289  119.786 127.148 1.00 20.00 ? 711 CLR A C4  1 
HETATM 4480 C  C5  . CLR L 5 .   ? 99.096  120.340 126.000 1.00 20.00 ? 711 CLR A C5  1 
HETATM 4481 C  C6  . CLR L 5 .   ? 99.417  119.528 124.980 1.00 20.00 ? 711 CLR A C6  1 
HETATM 4482 C  C7  . CLR L 5 .   ? 100.219 119.985 123.789 1.00 20.00 ? 711 CLR A C7  1 
HETATM 4483 C  C8  . CLR L 5 .   ? 101.073 121.166 124.208 1.00 20.00 ? 711 CLR A C8  1 
HETATM 4484 C  C9  . CLR L 5 .   ? 100.186 122.260 124.789 1.00 20.00 ? 711 CLR A C9  1 
HETATM 4485 C  C10 . CLR L 5 .   ? 99.498  121.795 126.063 1.00 20.00 ? 711 CLR A C10 1 
HETATM 4486 C  C11 . CLR L 5 .   ? 100.986 123.534 125.076 1.00 20.00 ? 711 CLR A C11 1 
HETATM 4487 C  C12 . CLR L 5 .   ? 101.880 123.984 123.919 1.00 20.00 ? 711 CLR A C12 1 
HETATM 4488 C  C13 . CLR L 5 .   ? 102.772 122.830 123.494 1.00 20.00 ? 711 CLR A C13 1 
HETATM 4489 C  C14 . CLR L 5 .   ? 101.852 121.727 123.032 1.00 20.00 ? 711 CLR A C14 1 
HETATM 4490 C  C15 . CLR L 5 .   ? 102.760 120.773 122.276 1.00 20.00 ? 711 CLR A C15 1 
HETATM 4491 C  C16 . CLR L 5 .   ? 103.775 121.698 121.604 1.00 20.00 ? 711 CLR A C16 1 
HETATM 4492 C  C17 . CLR L 5 .   ? 103.685 123.056 122.300 1.00 20.00 ? 711 CLR A C17 1 
HETATM 4493 C  C18 . CLR L 5 .   ? 103.638 122.350 124.658 1.00 20.00 ? 711 CLR A C18 1 
HETATM 4494 C  C19 . CLR L 5 .   ? 100.456 121.983 127.235 1.00 20.00 ? 711 CLR A C19 1 
HETATM 4495 C  C20 . CLR L 5 .   ? 105.058 123.605 122.679 1.00 20.00 ? 711 CLR A C20 1 
HETATM 4496 C  C21 . CLR L 5 .   ? 105.100 125.129 122.607 1.00 20.00 ? 711 CLR A C21 1 
HETATM 4497 C  C22 . CLR L 5 .   ? 106.162 123.010 121.813 1.00 20.00 ? 711 CLR A C22 1 
HETATM 4498 C  C23 . CLR L 5 .   ? 106.783 124.072 120.915 1.00 20.00 ? 711 CLR A C23 1 
HETATM 4499 C  C24 . CLR L 5 .   ? 108.007 123.516 120.199 1.00 20.00 ? 711 CLR A C24 1 
HETATM 4500 C  C25 . CLR L 5 .   ? 108.642 124.568 119.298 1.00 20.00 ? 711 CLR A C25 1 
HETATM 4501 C  C26 . CLR L 5 .   ? 107.675 125.002 118.204 1.00 20.00 ? 711 CLR A C26 1 
HETATM 4502 C  C27 . CLR L 5 .   ? 109.121 125.765 120.109 1.00 20.00 ? 711 CLR A C27 1 
HETATM 4503 O  O1  . CLR L 5 .   ? 96.316  120.196 128.473 1.00 20.00 ? 711 CLR A O1  1 
HETATM 4504 O  O   . HOH M 6 .   ? 97.834  101.463 114.508 1.00 30.00 ? 801 HOH A O   1 
HETATM 4505 O  O   . HOH M 6 .   ? 93.139  98.321  98.710  1.00 30.00 ? 802 HOH A O   1 
HETATM 4506 O  O   . HOH M 6 .   ? 112.540 99.381  110.947 1.00 30.00 ? 803 HOH A O   1 
HETATM 4507 O  O   . HOH M 6 .   ? 113.251 103.138 114.140 1.00 30.00 ? 804 HOH A O   1 
HETATM 4508 O  O   . HOH M 6 .   ? 90.130  103.522 107.470 1.00 30.00 ? 805 HOH A O   1 
HETATM 4509 O  O   . HOH M 6 .   ? 91.103  101.839 96.059  1.00 30.00 ? 806 HOH A O   1 
HETATM 4510 O  O   . HOH M 6 .   ? 110.011 109.092 106.898 1.00 30.00 ? 807 HOH A O   1 
HETATM 4511 O  O   . HOH M 6 .   ? 115.395 107.679 97.955  1.00 30.00 ? 808 HOH A O   1 
HETATM 4512 O  O   . HOH M 6 .   ? 114.354 104.462 107.976 1.00 30.00 ? 809 HOH A O   1 
HETATM 4513 O  O   . HOH M 6 .   ? 112.037 100.913 107.832 1.00 30.00 ? 810 HOH A O   1 
HETATM 4514 O  O   . HOH M 6 .   ? 87.373  101.051 106.772 1.00 30.00 ? 811 HOH A O   1 
HETATM 4515 O  O   . HOH M 6 .   ? 89.712  100.394 100.828 1.00 30.00 ? 812 HOH A O   1 
HETATM 4516 O  O   . HOH M 6 .   ? 116.133 102.233 93.427  1.00 30.00 ? 813 HOH A O   1 
HETATM 4517 O  O   . HOH M 6 .   ? 98.809  98.827  102.616 1.00 30.00 ? 814 HOH A O   1 
HETATM 4518 O  O   . HOH M 6 .   ? 96.475  101.817 96.781  1.00 30.00 ? 815 HOH A O   1 
HETATM 4519 O  O   . HOH M 6 .   ? 90.090  97.665  95.350  1.00 30.00 ? 816 HOH A O   1 
HETATM 4520 O  O   . HOH M 6 .   ? 115.530 102.373 111.898 1.00 30.00 ? 817 HOH A O   1 
HETATM 4521 O  O   . HOH M 6 .   ? 110.307 106.486 107.624 1.00 30.00 ? 818 HOH A O   1 
HETATM 4522 O  O   . HOH M 6 .   ? 118.274 106.094 103.003 1.00 30.00 ? 819 HOH A O   1 
# 
