data_9K6L
# 
_entry.id   9K6L 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9K6L         pdb_00009k6l 10.2210/pdb9k6l/pdb 
WWPDB D_1300052796 ?            ?                   
EMDB  EMD-62129    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-02 ? 
2 'EM metadata'     1 0 2025-04-02 ? 
3 FSC               1 0 2025-04-02 ? 
4 'Half map'        1 0 2025-04-02 1 
5 'Half map'        1 0 2025-04-02 2 
6 Image             1 0 2025-04-02 ? 
7 'Primary map'     1 0 2025-04-02 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9K6L 
_pdbx_database_status.recvd_initial_deposition_date   2024-10-22 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of GPCR16-Gi2 complex' 
_pdbx_database_related.db_id          EMD-62129 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 5 
_pdbx_contact_author.email              huatian@shanghaitech.edu.cn 
_pdbx_contact_author.name_first         Tian 
_pdbx_contact_author.name_last          Hua 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-6132-2068 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Wang, X.'  1 ? 
'Zhou, C.'  2 ? 
'Wu, L.J.'  3 ? 
'Hua, T.'   4 ? 
'Liu, Z.J.' 5 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Cryo-EM structure of GPCR16-Gi2 complex' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Wang, X.'  1 ? 
primary 'Zhou, C.'  2 ? 
primary 'Wu, L.J.'  3 ? 
primary 'Hua, T.'   4 ? 
primary 'Liu, Z.J.' 5 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Guanine nucleotide-binding protein G(i) subunit alpha-2'           40560.895  1 ?        'S47N, G204A, A327S' ? 
? 
2 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1'  39728.426  1 ?        ?                    ? 
? 
3 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2' 7861.143   1 ?        ?                    ? 
? 
4 polymer     man scFv16                                                              28666.820  1 ?        ?                    ? 
? 
5 polymer     man 'exo-alpha-sialidase,Taste receptor type 2 member 16,LgBiT'         113855.758 1 3.2.1.18 S133C                ? 
? 
6 non-polymer syn '2-(hydroxymethyl)phenyl beta-D-glucopyranoside'                    286.278    1 ?        ?                    ? 
? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Adenylate cyclase-inhibiting G alpha protein' 
2 'Transducin beta chain 1'                      
3 'G gamma-I'                                    
5 'Neuraminidase A,T2R16'                        
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKNTIVKQMKIIHEDGYSEEECRQYRAVVYSNTIQS
IMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDL
ERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGAQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEE
MNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFEDLNKRKDTKEI
YTHFTCSTDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
;MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKNTIVKQMKIIHEDGYSEEECRQYRAVVYSNTIQS
IMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDL
ERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGAQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEE
MNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFEDLNKRKDTKEI
YTHFTCSTDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
A ? 
2 'polypeptide(L)' no no 
;MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLI
IWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS
SGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA
FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGV
TDDGMAVATGSWDSFLKIWNGSSGGGGSGGGGSSGVSGWRLFKKIS
;
;MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLI
IWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS
SGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA
FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGV
TDDGMAVATGSWDSFLKIWNGSSGGGGSGGGGSSGVSGWRLFKKIS
;
B ? 
3 'polypeptide(L)' no no MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL G ? 
4 'polypeptide(L)' no no 
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLELKAAAENLYFQSHHHHHHHH
;
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLELKAAAENLYFQSHHHHHHHH
;
S ? 
5 'polypeptide(L)' no no 
;MKTIIALSYIFCLVFADYKDDDDAHHHHHHHHHHENLYFQSAHHHHHHSSGLEVLFQGPPEGAALTEKTDIFESGRNGNP
NKDGIKSYRIPALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASDPSIGSPVNIDM
VLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILYREGEKGAYTIRENGTVYTPDGKATDYRVVVDPV
KPAYSDKGDLYKGDQLLGNIYFTTNKTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRN
GPHKGRILIPVYTTNNVSHLDGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMNNRRAQNTESTVVQLNNGDV
KLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQMSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELT
WLKHNPIQKGEFAYNSLQELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNGSGSGIPIQLTVFFMIIYVLESLTII
VQSSLIVAVLGREWLQVRRLMPVDMILISLGISRFCLQWASMLNNFCSYFNLNYVLCNLTITWEFFNILTFWLNSLLTVF
YCIKVSSFTHHIFLWLRWRILRLFPWILLGCLMITCVTIIPSAIGNYIQIQLLTMEHLPRNSTVTDKLENFHQYQFQAHT
VALVIPFILFLASTIFLMASLTKQIQHHSTGHCNPSMKARFTALRSLAVLFIVFTSYFLTILITIIGTLFDKRCWLWVWE
AFVYAFILMHSTSLMLSSPTLKRILKGKCGSGSGGSGSGGSGSGGSGSGSSGGVFTLEDFVGDWEQTAAYNLDQVLEQGG
VSSLLQNLAVSVTPIQRIVRSGENALKIDIHVIIPYEGLSADQMAQIEEVFKVVYPVDDHHFKVILPYGTLVIDGVTPNM
LNYFGRPYEGIAVFDGKKITVTGTLWNGNKIIDERLITPDGSMLFRVTINS
;
;MKTIIALSYIFCLVFADYKDDDDAHHHHHHHHHHENLYFQSAHHHHHHSSGLEVLFQGPPEGAALTEKTDIFESGRNGNP
NKDGIKSYRIPALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASDPSIGSPVNIDM
VLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILYREGEKGAYTIRENGTVYTPDGKATDYRVVVDPV
KPAYSDKGDLYKGDQLLGNIYFTTNKTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRN
GPHKGRILIPVYTTNNVSHLDGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMNNRRAQNTESTVVQLNNGDV
KLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQMSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELT
WLKHNPIQKGEFAYNSLQELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNGSGSGIPIQLTVFFMIIYVLESLTII
VQSSLIVAVLGREWLQVRRLMPVDMILISLGISRFCLQWASMLNNFCSYFNLNYVLCNLTITWEFFNILTFWLNSLLTVF
YCIKVSSFTHHIFLWLRWRILRLFPWILLGCLMITCVTIIPSAIGNYIQIQLLTMEHLPRNSTVTDKLENFHQYQFQAHT
VALVIPFILFLASTIFLMASLTKQIQHHSTGHCNPSMKARFTALRSLAVLFIVFTSYFLTILITIIGTLFDKRCWLWVWE
AFVYAFILMHSTSLMLSSPTLKRILKGKCGSGSGGSGSGGSGSGGSGSGSSGGVFTLEDFVGDWEQTAAYNLDQVLEQGG
VSSLLQNLAVSVTPIQRIVRSGENALKIDIHVIIPYEGLSADQMAQIEEVFKVVYPVDDHHFKVILPYGTLVIDGVTPNM
LNYFGRPYEGIAVFDGKKITVTGTLWNGNKIIDERLITPDGSMLFRVTINS
;
R ? 
# 
_pdbx_entity_nonpoly.entity_id   6 
_pdbx_entity_nonpoly.name        '2-(hydroxymethyl)phenyl beta-D-glucopyranoside' 
_pdbx_entity_nonpoly.comp_id     SA0 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1    MET n 
1 2    GLY n 
1 3    CYS n 
1 4    THR n 
1 5    VAL n 
1 6    SER n 
1 7    ALA n 
1 8    GLU n 
1 9    ASP n 
1 10   LYS n 
1 11   ALA n 
1 12   ALA n 
1 13   ALA n 
1 14   GLU n 
1 15   ARG n 
1 16   SER n 
1 17   LYS n 
1 18   MET n 
1 19   ILE n 
1 20   ASP n 
1 21   LYS n 
1 22   ASN n 
1 23   LEU n 
1 24   ARG n 
1 25   GLU n 
1 26   ASP n 
1 27   GLY n 
1 28   GLU n 
1 29   LYS n 
1 30   ALA n 
1 31   ALA n 
1 32   ARG n 
1 33   GLU n 
1 34   VAL n 
1 35   LYS n 
1 36   LEU n 
1 37   LEU n 
1 38   LEU n 
1 39   LEU n 
1 40   GLY n 
1 41   ALA n 
1 42   GLY n 
1 43   GLU n 
1 44   SER n 
1 45   GLY n 
1 46   LYS n 
1 47   ASN n 
1 48   THR n 
1 49   ILE n 
1 50   VAL n 
1 51   LYS n 
1 52   GLN n 
1 53   MET n 
1 54   LYS n 
1 55   ILE n 
1 56   ILE n 
1 57   HIS n 
1 58   GLU n 
1 59   ASP n 
1 60   GLY n 
1 61   TYR n 
1 62   SER n 
1 63   GLU n 
1 64   GLU n 
1 65   GLU n 
1 66   CYS n 
1 67   ARG n 
1 68   GLN n 
1 69   TYR n 
1 70   ARG n 
1 71   ALA n 
1 72   VAL n 
1 73   VAL n 
1 74   TYR n 
1 75   SER n 
1 76   ASN n 
1 77   THR n 
1 78   ILE n 
1 79   GLN n 
1 80   SER n 
1 81   ILE n 
1 82   MET n 
1 83   ALA n 
1 84   ILE n 
1 85   VAL n 
1 86   LYS n 
1 87   ALA n 
1 88   MET n 
1 89   GLY n 
1 90   ASN n 
1 91   LEU n 
1 92   GLN n 
1 93   ILE n 
1 94   ASP n 
1 95   PHE n 
1 96   ALA n 
1 97   ASP n 
1 98   PRO n 
1 99   SER n 
1 100  ARG n 
1 101  ALA n 
1 102  ASP n 
1 103  ASP n 
1 104  ALA n 
1 105  ARG n 
1 106  GLN n 
1 107  LEU n 
1 108  PHE n 
1 109  ALA n 
1 110  LEU n 
1 111  SER n 
1 112  CYS n 
1 113  THR n 
1 114  ALA n 
1 115  GLU n 
1 116  GLU n 
1 117  GLN n 
1 118  GLY n 
1 119  VAL n 
1 120  LEU n 
1 121  PRO n 
1 122  ASP n 
1 123  ASP n 
1 124  LEU n 
1 125  SER n 
1 126  GLY n 
1 127  VAL n 
1 128  ILE n 
1 129  ARG n 
1 130  ARG n 
1 131  LEU n 
1 132  TRP n 
1 133  ALA n 
1 134  ASP n 
1 135  HIS n 
1 136  GLY n 
1 137  VAL n 
1 138  GLN n 
1 139  ALA n 
1 140  CYS n 
1 141  PHE n 
1 142  GLY n 
1 143  ARG n 
1 144  SER n 
1 145  ARG n 
1 146  GLU n 
1 147  TYR n 
1 148  GLN n 
1 149  LEU n 
1 150  ASN n 
1 151  ASP n 
1 152  SER n 
1 153  ALA n 
1 154  ALA n 
1 155  TYR n 
1 156  TYR n 
1 157  LEU n 
1 158  ASN n 
1 159  ASP n 
1 160  LEU n 
1 161  GLU n 
1 162  ARG n 
1 163  ILE n 
1 164  ALA n 
1 165  GLN n 
1 166  SER n 
1 167  ASP n 
1 168  TYR n 
1 169  ILE n 
1 170  PRO n 
1 171  THR n 
1 172  GLN n 
1 173  GLN n 
1 174  ASP n 
1 175  VAL n 
1 176  LEU n 
1 177  ARG n 
1 178  THR n 
1 179  ARG n 
1 180  VAL n 
1 181  LYS n 
1 182  THR n 
1 183  THR n 
1 184  GLY n 
1 185  ILE n 
1 186  VAL n 
1 187  GLU n 
1 188  THR n 
1 189  HIS n 
1 190  PHE n 
1 191  THR n 
1 192  PHE n 
1 193  LYS n 
1 194  ASP n 
1 195  LEU n 
1 196  HIS n 
1 197  PHE n 
1 198  LYS n 
1 199  MET n 
1 200  PHE n 
1 201  ASP n 
1 202  VAL n 
1 203  GLY n 
1 204  ALA n 
1 205  GLN n 
1 206  ARG n 
1 207  SER n 
1 208  GLU n 
1 209  ARG n 
1 210  LYS n 
1 211  LYS n 
1 212  TRP n 
1 213  ILE n 
1 214  HIS n 
1 215  CYS n 
1 216  PHE n 
1 217  GLU n 
1 218  GLY n 
1 219  VAL n 
1 220  THR n 
1 221  ALA n 
1 222  ILE n 
1 223  ILE n 
1 224  PHE n 
1 225  CYS n 
1 226  VAL n 
1 227  ALA n 
1 228  LEU n 
1 229  SER n 
1 230  ALA n 
1 231  TYR n 
1 232  ASP n 
1 233  LEU n 
1 234  VAL n 
1 235  LEU n 
1 236  ALA n 
1 237  GLU n 
1 238  ASP n 
1 239  GLU n 
1 240  GLU n 
1 241  MET n 
1 242  ASN n 
1 243  ARG n 
1 244  MET n 
1 245  HIS n 
1 246  GLU n 
1 247  SER n 
1 248  MET n 
1 249  LYS n 
1 250  LEU n 
1 251  PHE n 
1 252  ASP n 
1 253  SER n 
1 254  ILE n 
1 255  CYS n 
1 256  ASN n 
1 257  ASN n 
1 258  LYS n 
1 259  TRP n 
1 260  PHE n 
1 261  THR n 
1 262  ASP n 
1 263  THR n 
1 264  SER n 
1 265  ILE n 
1 266  ILE n 
1 267  LEU n 
1 268  PHE n 
1 269  LEU n 
1 270  ASN n 
1 271  LYS n 
1 272  LYS n 
1 273  ASP n 
1 274  LEU n 
1 275  PHE n 
1 276  GLU n 
1 277  GLU n 
1 278  LYS n 
1 279  ILE n 
1 280  THR n 
1 281  HIS n 
1 282  SER n 
1 283  PRO n 
1 284  LEU n 
1 285  THR n 
1 286  ILE n 
1 287  CYS n 
1 288  PHE n 
1 289  PRO n 
1 290  GLU n 
1 291  TYR n 
1 292  THR n 
1 293  GLY n 
1 294  ALA n 
1 295  ASN n 
1 296  LYS n 
1 297  TYR n 
1 298  ASP n 
1 299  GLU n 
1 300  ALA n 
1 301  ALA n 
1 302  SER n 
1 303  TYR n 
1 304  ILE n 
1 305  GLN n 
1 306  SER n 
1 307  LYS n 
1 308  PHE n 
1 309  GLU n 
1 310  ASP n 
1 311  LEU n 
1 312  ASN n 
1 313  LYS n 
1 314  ARG n 
1 315  LYS n 
1 316  ASP n 
1 317  THR n 
1 318  LYS n 
1 319  GLU n 
1 320  ILE n 
1 321  TYR n 
1 322  THR n 
1 323  HIS n 
1 324  PHE n 
1 325  THR n 
1 326  CYS n 
1 327  SER n 
1 328  THR n 
1 329  ASP n 
1 330  THR n 
1 331  LYS n 
1 332  ASN n 
1 333  VAL n 
1 334  GLN n 
1 335  PHE n 
1 336  VAL n 
1 337  PHE n 
1 338  ASP n 
1 339  ALA n 
1 340  VAL n 
1 341  THR n 
1 342  ASP n 
1 343  VAL n 
1 344  ILE n 
1 345  ILE n 
1 346  LYS n 
1 347  ASN n 
1 348  ASN n 
1 349  LEU n 
1 350  LYS n 
1 351  ASP n 
1 352  CYS n 
1 353  GLY n 
1 354  LEU n 
1 355  PHE n 
2 1    MET n 
2 2    SER n 
2 3    GLU n 
2 4    LEU n 
2 5    ASP n 
2 6    GLN n 
2 7    LEU n 
2 8    ARG n 
2 9    GLN n 
2 10   GLU n 
2 11   ALA n 
2 12   GLU n 
2 13   GLN n 
2 14   LEU n 
2 15   LYS n 
2 16   ASN n 
2 17   GLN n 
2 18   ILE n 
2 19   ARG n 
2 20   ASP n 
2 21   ALA n 
2 22   ARG n 
2 23   LYS n 
2 24   ALA n 
2 25   CYS n 
2 26   ALA n 
2 27   ASP n 
2 28   ALA n 
2 29   THR n 
2 30   LEU n 
2 31   SER n 
2 32   GLN n 
2 33   ILE n 
2 34   THR n 
2 35   ASN n 
2 36   ASN n 
2 37   ILE n 
2 38   ASP n 
2 39   PRO n 
2 40   VAL n 
2 41   GLY n 
2 42   ARG n 
2 43   ILE n 
2 44   GLN n 
2 45   MET n 
2 46   ARG n 
2 47   THR n 
2 48   ARG n 
2 49   ARG n 
2 50   THR n 
2 51   LEU n 
2 52   ARG n 
2 53   GLY n 
2 54   HIS n 
2 55   LEU n 
2 56   ALA n 
2 57   LYS n 
2 58   ILE n 
2 59   TYR n 
2 60   ALA n 
2 61   MET n 
2 62   HIS n 
2 63   TRP n 
2 64   GLY n 
2 65   THR n 
2 66   ASP n 
2 67   SER n 
2 68   ARG n 
2 69   LEU n 
2 70   LEU n 
2 71   VAL n 
2 72   SER n 
2 73   ALA n 
2 74   SER n 
2 75   GLN n 
2 76   ASP n 
2 77   GLY n 
2 78   LYS n 
2 79   LEU n 
2 80   ILE n 
2 81   ILE n 
2 82   TRP n 
2 83   ASP n 
2 84   SER n 
2 85   TYR n 
2 86   THR n 
2 87   THR n 
2 88   ASN n 
2 89   LYS n 
2 90   VAL n 
2 91   HIS n 
2 92   ALA n 
2 93   ILE n 
2 94   PRO n 
2 95   LEU n 
2 96   ARG n 
2 97   SER n 
2 98   SER n 
2 99   TRP n 
2 100  VAL n 
2 101  MET n 
2 102  THR n 
2 103  CYS n 
2 104  ALA n 
2 105  TYR n 
2 106  ALA n 
2 107  PRO n 
2 108  SER n 
2 109  GLY n 
2 110  ASN n 
2 111  TYR n 
2 112  VAL n 
2 113  ALA n 
2 114  CYS n 
2 115  GLY n 
2 116  GLY n 
2 117  LEU n 
2 118  ASP n 
2 119  ASN n 
2 120  ILE n 
2 121  CYS n 
2 122  SER n 
2 123  ILE n 
2 124  TYR n 
2 125  ASN n 
2 126  LEU n 
2 127  LYS n 
2 128  THR n 
2 129  ARG n 
2 130  GLU n 
2 131  GLY n 
2 132  ASN n 
2 133  VAL n 
2 134  ARG n 
2 135  VAL n 
2 136  SER n 
2 137  ARG n 
2 138  GLU n 
2 139  LEU n 
2 140  ALA n 
2 141  GLY n 
2 142  HIS n 
2 143  THR n 
2 144  GLY n 
2 145  TYR n 
2 146  LEU n 
2 147  SER n 
2 148  CYS n 
2 149  CYS n 
2 150  ARG n 
2 151  PHE n 
2 152  LEU n 
2 153  ASP n 
2 154  ASP n 
2 155  ASN n 
2 156  GLN n 
2 157  ILE n 
2 158  VAL n 
2 159  THR n 
2 160  SER n 
2 161  SER n 
2 162  GLY n 
2 163  ASP n 
2 164  THR n 
2 165  THR n 
2 166  CYS n 
2 167  ALA n 
2 168  LEU n 
2 169  TRP n 
2 170  ASP n 
2 171  ILE n 
2 172  GLU n 
2 173  THR n 
2 174  GLY n 
2 175  GLN n 
2 176  GLN n 
2 177  THR n 
2 178  THR n 
2 179  THR n 
2 180  PHE n 
2 181  THR n 
2 182  GLY n 
2 183  HIS n 
2 184  THR n 
2 185  GLY n 
2 186  ASP n 
2 187  VAL n 
2 188  MET n 
2 189  SER n 
2 190  LEU n 
2 191  SER n 
2 192  LEU n 
2 193  ALA n 
2 194  PRO n 
2 195  ASP n 
2 196  THR n 
2 197  ARG n 
2 198  LEU n 
2 199  PHE n 
2 200  VAL n 
2 201  SER n 
2 202  GLY n 
2 203  ALA n 
2 204  CYS n 
2 205  ASP n 
2 206  ALA n 
2 207  SER n 
2 208  ALA n 
2 209  LYS n 
2 210  LEU n 
2 211  TRP n 
2 212  ASP n 
2 213  VAL n 
2 214  ARG n 
2 215  GLU n 
2 216  GLY n 
2 217  MET n 
2 218  CYS n 
2 219  ARG n 
2 220  GLN n 
2 221  THR n 
2 222  PHE n 
2 223  THR n 
2 224  GLY n 
2 225  HIS n 
2 226  GLU n 
2 227  SER n 
2 228  ASP n 
2 229  ILE n 
2 230  ASN n 
2 231  ALA n 
2 232  ILE n 
2 233  CYS n 
2 234  PHE n 
2 235  PHE n 
2 236  PRO n 
2 237  ASN n 
2 238  GLY n 
2 239  ASN n 
2 240  ALA n 
2 241  PHE n 
2 242  ALA n 
2 243  THR n 
2 244  GLY n 
2 245  SER n 
2 246  ASP n 
2 247  ASP n 
2 248  ALA n 
2 249  THR n 
2 250  CYS n 
2 251  ARG n 
2 252  LEU n 
2 253  PHE n 
2 254  ASP n 
2 255  LEU n 
2 256  ARG n 
2 257  ALA n 
2 258  ASP n 
2 259  GLN n 
2 260  GLU n 
2 261  LEU n 
2 262  MET n 
2 263  THR n 
2 264  TYR n 
2 265  SER n 
2 266  HIS n 
2 267  ASP n 
2 268  ASN n 
2 269  ILE n 
2 270  ILE n 
2 271  CYS n 
2 272  GLY n 
2 273  ILE n 
2 274  THR n 
2 275  SER n 
2 276  VAL n 
2 277  SER n 
2 278  PHE n 
2 279  SER n 
2 280  LYS n 
2 281  SER n 
2 282  GLY n 
2 283  ARG n 
2 284  LEU n 
2 285  LEU n 
2 286  LEU n 
2 287  ALA n 
2 288  GLY n 
2 289  TYR n 
2 290  ASP n 
2 291  ASP n 
2 292  PHE n 
2 293  ASN n 
2 294  CYS n 
2 295  ASN n 
2 296  VAL n 
2 297  TRP n 
2 298  ASP n 
2 299  ALA n 
2 300  LEU n 
2 301  LYS n 
2 302  ALA n 
2 303  ASP n 
2 304  ARG n 
2 305  ALA n 
2 306  GLY n 
2 307  VAL n 
2 308  LEU n 
2 309  ALA n 
2 310  GLY n 
2 311  HIS n 
2 312  ASP n 
2 313  ASN n 
2 314  ARG n 
2 315  VAL n 
2 316  SER n 
2 317  CYS n 
2 318  LEU n 
2 319  GLY n 
2 320  VAL n 
2 321  THR n 
2 322  ASP n 
2 323  ASP n 
2 324  GLY n 
2 325  MET n 
2 326  ALA n 
2 327  VAL n 
2 328  ALA n 
2 329  THR n 
2 330  GLY n 
2 331  SER n 
2 332  TRP n 
2 333  ASP n 
2 334  SER n 
2 335  PHE n 
2 336  LEU n 
2 337  LYS n 
2 338  ILE n 
2 339  TRP n 
2 340  ASN n 
2 341  GLY n 
2 342  SER n 
2 343  SER n 
2 344  GLY n 
2 345  GLY n 
2 346  GLY n 
2 347  GLY n 
2 348  SER n 
2 349  GLY n 
2 350  GLY n 
2 351  GLY n 
2 352  GLY n 
2 353  SER n 
2 354  SER n 
2 355  GLY n 
2 356  VAL n 
2 357  SER n 
2 358  GLY n 
2 359  TRP n 
2 360  ARG n 
2 361  LEU n 
2 362  PHE n 
2 363  LYS n 
2 364  LYS n 
2 365  ILE n 
2 366  SER n 
3 1    MET n 
3 2    ALA n 
3 3    SER n 
3 4    ASN n 
3 5    ASN n 
3 6    THR n 
3 7    ALA n 
3 8    SER n 
3 9    ILE n 
3 10   ALA n 
3 11   GLN n 
3 12   ALA n 
3 13   ARG n 
3 14   LYS n 
3 15   LEU n 
3 16   VAL n 
3 17   GLU n 
3 18   GLN n 
3 19   LEU n 
3 20   LYS n 
3 21   MET n 
3 22   GLU n 
3 23   ALA n 
3 24   ASN n 
3 25   ILE n 
3 26   ASP n 
3 27   ARG n 
3 28   ILE n 
3 29   LYS n 
3 30   VAL n 
3 31   SER n 
3 32   LYS n 
3 33   ALA n 
3 34   ALA n 
3 35   ALA n 
3 36   ASP n 
3 37   LEU n 
3 38   MET n 
3 39   ALA n 
3 40   TYR n 
3 41   CYS n 
3 42   GLU n 
3 43   ALA n 
3 44   HIS n 
3 45   ALA n 
3 46   LYS n 
3 47   GLU n 
3 48   ASP n 
3 49   PRO n 
3 50   LEU n 
3 51   LEU n 
3 52   THR n 
3 53   PRO n 
3 54   VAL n 
3 55   PRO n 
3 56   ALA n 
3 57   SER n 
3 58   GLU n 
3 59   ASN n 
3 60   PRO n 
3 61   PHE n 
3 62   ARG n 
3 63   GLU n 
3 64   LYS n 
3 65   LYS n 
3 66   PHE n 
3 67   PHE n 
3 68   CYS n 
3 69   ALA n 
3 70   ILE n 
3 71   LEU n 
4 1    ASP n 
4 2    VAL n 
4 3    GLN n 
4 4    LEU n 
4 5    VAL n 
4 6    GLU n 
4 7    SER n 
4 8    GLY n 
4 9    GLY n 
4 10   GLY n 
4 11   LEU n 
4 12   VAL n 
4 13   GLN n 
4 14   PRO n 
4 15   GLY n 
4 16   GLY n 
4 17   SER n 
4 18   ARG n 
4 19   LYS n 
4 20   LEU n 
4 21   SER n 
4 22   CYS n 
4 23   SER n 
4 24   ALA n 
4 25   SER n 
4 26   GLY n 
4 27   PHE n 
4 28   ALA n 
4 29   PHE n 
4 30   SER n 
4 31   SER n 
4 32   PHE n 
4 33   GLY n 
4 34   MET n 
4 35   HIS n 
4 36   TRP n 
4 37   VAL n 
4 38   ARG n 
4 39   GLN n 
4 40   ALA n 
4 41   PRO n 
4 42   GLU n 
4 43   LYS n 
4 44   GLY n 
4 45   LEU n 
4 46   GLU n 
4 47   TRP n 
4 48   VAL n 
4 49   ALA n 
4 50   TYR n 
4 51   ILE n 
4 52   SER n 
4 53   SER n 
4 54   GLY n 
4 55   SER n 
4 56   GLY n 
4 57   THR n 
4 58   ILE n 
4 59   TYR n 
4 60   TYR n 
4 61   ALA n 
4 62   ASP n 
4 63   THR n 
4 64   VAL n 
4 65   LYS n 
4 66   GLY n 
4 67   ARG n 
4 68   PHE n 
4 69   THR n 
4 70   ILE n 
4 71   SER n 
4 72   ARG n 
4 73   ASP n 
4 74   ASP n 
4 75   PRO n 
4 76   LYS n 
4 77   ASN n 
4 78   THR n 
4 79   LEU n 
4 80   PHE n 
4 81   LEU n 
4 82   GLN n 
4 83   MET n 
4 84   THR n 
4 85   SER n 
4 86   LEU n 
4 87   ARG n 
4 88   SER n 
4 89   GLU n 
4 90   ASP n 
4 91   THR n 
4 92   ALA n 
4 93   MET n 
4 94   TYR n 
4 95   TYR n 
4 96   CYS n 
4 97   VAL n 
4 98   ARG n 
4 99   SER n 
4 100  ILE n 
4 101  TYR n 
4 102  TYR n 
4 103  TYR n 
4 104  GLY n 
4 105  SER n 
4 106  SER n 
4 107  PRO n 
4 108  PHE n 
4 109  ASP n 
4 110  PHE n 
4 111  TRP n 
4 112  GLY n 
4 113  GLN n 
4 114  GLY n 
4 115  THR n 
4 116  THR n 
4 117  LEU n 
4 118  THR n 
4 119  VAL n 
4 120  SER n 
4 121  SER n 
4 122  GLY n 
4 123  GLY n 
4 124  GLY n 
4 125  GLY n 
4 126  SER n 
4 127  GLY n 
4 128  GLY n 
4 129  GLY n 
4 130  GLY n 
4 131  SER n 
4 132  GLY n 
4 133  GLY n 
4 134  GLY n 
4 135  GLY n 
4 136  SER n 
4 137  ASP n 
4 138  ILE n 
4 139  VAL n 
4 140  MET n 
4 141  THR n 
4 142  GLN n 
4 143  ALA n 
4 144  THR n 
4 145  SER n 
4 146  SER n 
4 147  VAL n 
4 148  PRO n 
4 149  VAL n 
4 150  THR n 
4 151  PRO n 
4 152  GLY n 
4 153  GLU n 
4 154  SER n 
4 155  VAL n 
4 156  SER n 
4 157  ILE n 
4 158  SER n 
4 159  CYS n 
4 160  ARG n 
4 161  SER n 
4 162  SER n 
4 163  LYS n 
4 164  SER n 
4 165  LEU n 
4 166  LEU n 
4 167  HIS n 
4 168  SER n 
4 169  ASN n 
4 170  GLY n 
4 171  ASN n 
4 172  THR n 
4 173  TYR n 
4 174  LEU n 
4 175  TYR n 
4 176  TRP n 
4 177  PHE n 
4 178  LEU n 
4 179  GLN n 
4 180  ARG n 
4 181  PRO n 
4 182  GLY n 
4 183  GLN n 
4 184  SER n 
4 185  PRO n 
4 186  GLN n 
4 187  LEU n 
4 188  LEU n 
4 189  ILE n 
4 190  TYR n 
4 191  ARG n 
4 192  MET n 
4 193  SER n 
4 194  ASN n 
4 195  LEU n 
4 196  ALA n 
4 197  SER n 
4 198  GLY n 
4 199  VAL n 
4 200  PRO n 
4 201  ASP n 
4 202  ARG n 
4 203  PHE n 
4 204  SER n 
4 205  GLY n 
4 206  SER n 
4 207  GLY n 
4 208  SER n 
4 209  GLY n 
4 210  THR n 
4 211  ALA n 
4 212  PHE n 
4 213  THR n 
4 214  LEU n 
4 215  THR n 
4 216  ILE n 
4 217  SER n 
4 218  ARG n 
4 219  LEU n 
4 220  GLU n 
4 221  ALA n 
4 222  GLU n 
4 223  ASP n 
4 224  VAL n 
4 225  GLY n 
4 226  VAL n 
4 227  TYR n 
4 228  TYR n 
4 229  CYS n 
4 230  MET n 
4 231  GLN n 
4 232  HIS n 
4 233  LEU n 
4 234  GLU n 
4 235  TYR n 
4 236  PRO n 
4 237  LEU n 
4 238  THR n 
4 239  PHE n 
4 240  GLY n 
4 241  ALA n 
4 242  GLY n 
4 243  THR n 
4 244  LYS n 
4 245  LEU n 
4 246  GLU n 
4 247  LEU n 
4 248  LYS n 
4 249  ALA n 
4 250  ALA n 
4 251  ALA n 
4 252  GLU n 
4 253  ASN n 
4 254  LEU n 
4 255  TYR n 
4 256  PHE n 
4 257  GLN n 
4 258  SER n 
4 259  HIS n 
4 260  HIS n 
4 261  HIS n 
4 262  HIS n 
4 263  HIS n 
4 264  HIS n 
4 265  HIS n 
4 266  HIS n 
5 1    MET n 
5 2    LYS n 
5 3    THR n 
5 4    ILE n 
5 5    ILE n 
5 6    ALA n 
5 7    LEU n 
5 8    SER n 
5 9    TYR n 
5 10   ILE n 
5 11   PHE n 
5 12   CYS n 
5 13   LEU n 
5 14   VAL n 
5 15   PHE n 
5 16   ALA n 
5 17   ASP n 
5 18   TYR n 
5 19   LYS n 
5 20   ASP n 
5 21   ASP n 
5 22   ASP n 
5 23   ASP n 
5 24   ALA n 
5 25   HIS n 
5 26   HIS n 
5 27   HIS n 
5 28   HIS n 
5 29   HIS n 
5 30   HIS n 
5 31   HIS n 
5 32   HIS n 
5 33   HIS n 
5 34   HIS n 
5 35   GLU n 
5 36   ASN n 
5 37   LEU n 
5 38   TYR n 
5 39   PHE n 
5 40   GLN n 
5 41   SER n 
5 42   ALA n 
5 43   HIS n 
5 44   HIS n 
5 45   HIS n 
5 46   HIS n 
5 47   HIS n 
5 48   HIS n 
5 49   SER n 
5 50   SER n 
5 51   GLY n 
5 52   LEU n 
5 53   GLU n 
5 54   VAL n 
5 55   LEU n 
5 56   PHE n 
5 57   GLN n 
5 58   GLY n 
5 59   PRO n 
5 60   PRO n 
5 61   GLU n 
5 62   GLY n 
5 63   ALA n 
5 64   ALA n 
5 65   LEU n 
5 66   THR n 
5 67   GLU n 
5 68   LYS n 
5 69   THR n 
5 70   ASP n 
5 71   ILE n 
5 72   PHE n 
5 73   GLU n 
5 74   SER n 
5 75   GLY n 
5 76   ARG n 
5 77   ASN n 
5 78   GLY n 
5 79   ASN n 
5 80   PRO n 
5 81   ASN n 
5 82   LYS n 
5 83   ASP n 
5 84   GLY n 
5 85   ILE n 
5 86   LYS n 
5 87   SER n 
5 88   TYR n 
5 89   ARG n 
5 90   ILE n 
5 91   PRO n 
5 92   ALA n 
5 93   LEU n 
5 94   LEU n 
5 95   LYS n 
5 96   THR n 
5 97   ASP n 
5 98   LYS n 
5 99   GLY n 
5 100  THR n 
5 101  LEU n 
5 102  ILE n 
5 103  ALA n 
5 104  GLY n 
5 105  ALA n 
5 106  ASP n 
5 107  GLU n 
5 108  ARG n 
5 109  ARG n 
5 110  LEU n 
5 111  HIS n 
5 112  SER n 
5 113  SER n 
5 114  ASP n 
5 115  TRP n 
5 116  GLY n 
5 117  ASP n 
5 118  ILE n 
5 119  GLY n 
5 120  MET n 
5 121  VAL n 
5 122  ILE n 
5 123  ARG n 
5 124  ARG n 
5 125  SER n 
5 126  GLU n 
5 127  ASP n 
5 128  ASN n 
5 129  GLY n 
5 130  LYS n 
5 131  THR n 
5 132  TRP n 
5 133  GLY n 
5 134  ASP n 
5 135  ARG n 
5 136  VAL n 
5 137  THR n 
5 138  ILE n 
5 139  THR n 
5 140  ASN n 
5 141  LEU n 
5 142  ARG n 
5 143  ASP n 
5 144  ASN n 
5 145  PRO n 
5 146  LYS n 
5 147  ALA n 
5 148  SER n 
5 149  ASP n 
5 150  PRO n 
5 151  SER n 
5 152  ILE n 
5 153  GLY n 
5 154  SER n 
5 155  PRO n 
5 156  VAL n 
5 157  ASN n 
5 158  ILE n 
5 159  ASP n 
5 160  MET n 
5 161  VAL n 
5 162  LEU n 
5 163  VAL n 
5 164  GLN n 
5 165  ASP n 
5 166  PRO n 
5 167  GLU n 
5 168  THR n 
5 169  LYS n 
5 170  ARG n 
5 171  ILE n 
5 172  PHE n 
5 173  SER n 
5 174  ILE n 
5 175  TYR n 
5 176  ASP n 
5 177  MET n 
5 178  PHE n 
5 179  PRO n 
5 180  GLU n 
5 181  GLY n 
5 182  LYS n 
5 183  GLY n 
5 184  ILE n 
5 185  PHE n 
5 186  GLY n 
5 187  MET n 
5 188  SER n 
5 189  SER n 
5 190  GLN n 
5 191  LYS n 
5 192  GLU n 
5 193  GLU n 
5 194  ALA n 
5 195  TYR n 
5 196  LYS n 
5 197  LYS n 
5 198  ILE n 
5 199  ASP n 
5 200  GLY n 
5 201  LYS n 
5 202  THR n 
5 203  TYR n 
5 204  GLN n 
5 205  ILE n 
5 206  LEU n 
5 207  TYR n 
5 208  ARG n 
5 209  GLU n 
5 210  GLY n 
5 211  GLU n 
5 212  LYS n 
5 213  GLY n 
5 214  ALA n 
5 215  TYR n 
5 216  THR n 
5 217  ILE n 
5 218  ARG n 
5 219  GLU n 
5 220  ASN n 
5 221  GLY n 
5 222  THR n 
5 223  VAL n 
5 224  TYR n 
5 225  THR n 
5 226  PRO n 
5 227  ASP n 
5 228  GLY n 
5 229  LYS n 
5 230  ALA n 
5 231  THR n 
5 232  ASP n 
5 233  TYR n 
5 234  ARG n 
5 235  VAL n 
5 236  VAL n 
5 237  VAL n 
5 238  ASP n 
5 239  PRO n 
5 240  VAL n 
5 241  LYS n 
5 242  PRO n 
5 243  ALA n 
5 244  TYR n 
5 245  SER n 
5 246  ASP n 
5 247  LYS n 
5 248  GLY n 
5 249  ASP n 
5 250  LEU n 
5 251  TYR n 
5 252  LYS n 
5 253  GLY n 
5 254  ASP n 
5 255  GLN n 
5 256  LEU n 
5 257  LEU n 
5 258  GLY n 
5 259  ASN n 
5 260  ILE n 
5 261  TYR n 
5 262  PHE n 
5 263  THR n 
5 264  THR n 
5 265  ASN n 
5 266  LYS n 
5 267  THR n 
5 268  SER n 
5 269  PRO n 
5 270  PHE n 
5 271  ARG n 
5 272  ILE n 
5 273  ALA n 
5 274  LYS n 
5 275  ASP n 
5 276  SER n 
5 277  TYR n 
5 278  LEU n 
5 279  TRP n 
5 280  MET n 
5 281  SER n 
5 282  TYR n 
5 283  SER n 
5 284  ASP n 
5 285  ASP n 
5 286  ASP n 
5 287  GLY n 
5 288  LYS n 
5 289  THR n 
5 290  TRP n 
5 291  SER n 
5 292  ALA n 
5 293  PRO n 
5 294  GLN n 
5 295  ASP n 
5 296  ILE n 
5 297  THR n 
5 298  PRO n 
5 299  MET n 
5 300  VAL n 
5 301  LYS n 
5 302  ALA n 
5 303  ASP n 
5 304  TRP n 
5 305  MET n 
5 306  LYS n 
5 307  PHE n 
5 308  LEU n 
5 309  GLY n 
5 310  VAL n 
5 311  GLY n 
5 312  PRO n 
5 313  GLY n 
5 314  THR n 
5 315  GLY n 
5 316  ILE n 
5 317  VAL n 
5 318  LEU n 
5 319  ARG n 
5 320  ASN n 
5 321  GLY n 
5 322  PRO n 
5 323  HIS n 
5 324  LYS n 
5 325  GLY n 
5 326  ARG n 
5 327  ILE n 
5 328  LEU n 
5 329  ILE n 
5 330  PRO n 
5 331  VAL n 
5 332  TYR n 
5 333  THR n 
5 334  THR n 
5 335  ASN n 
5 336  ASN n 
5 337  VAL n 
5 338  SER n 
5 339  HIS n 
5 340  LEU n 
5 341  ASP n 
5 342  GLY n 
5 343  SER n 
5 344  GLN n 
5 345  SER n 
5 346  SER n 
5 347  ARG n 
5 348  VAL n 
5 349  ILE n 
5 350  TYR n 
5 351  SER n 
5 352  ASP n 
5 353  ASP n 
5 354  HIS n 
5 355  GLY n 
5 356  LYS n 
5 357  THR n 
5 358  TRP n 
5 359  HIS n 
5 360  ALA n 
5 361  GLY n 
5 362  GLU n 
5 363  ALA n 
5 364  VAL n 
5 365  ASN n 
5 366  ASP n 
5 367  ASN n 
5 368  ARG n 
5 369  GLN n 
5 370  VAL n 
5 371  ASP n 
5 372  GLY n 
5 373  GLN n 
5 374  LYS n 
5 375  ILE n 
5 376  HIS n 
5 377  SER n 
5 378  SER n 
5 379  THR n 
5 380  MET n 
5 381  ASN n 
5 382  ASN n 
5 383  ARG n 
5 384  ARG n 
5 385  ALA n 
5 386  GLN n 
5 387  ASN n 
5 388  THR n 
5 389  GLU n 
5 390  SER n 
5 391  THR n 
5 392  VAL n 
5 393  VAL n 
5 394  GLN n 
5 395  LEU n 
5 396  ASN n 
5 397  ASN n 
5 398  GLY n 
5 399  ASP n 
5 400  VAL n 
5 401  LYS n 
5 402  LEU n 
5 403  PHE n 
5 404  MET n 
5 405  ARG n 
5 406  GLY n 
5 407  LEU n 
5 408  THR n 
5 409  GLY n 
5 410  ASP n 
5 411  LEU n 
5 412  GLN n 
5 413  VAL n 
5 414  ALA n 
5 415  THR n 
5 416  SER n 
5 417  LYS n 
5 418  ASP n 
5 419  GLY n 
5 420  GLY n 
5 421  VAL n 
5 422  THR n 
5 423  TRP n 
5 424  GLU n 
5 425  LYS n 
5 426  ASP n 
5 427  ILE n 
5 428  LYS n 
5 429  ARG n 
5 430  TYR n 
5 431  PRO n 
5 432  GLN n 
5 433  VAL n 
5 434  LYS n 
5 435  ASP n 
5 436  VAL n 
5 437  TYR n 
5 438  VAL n 
5 439  GLN n 
5 440  MET n 
5 441  SER n 
5 442  ALA n 
5 443  ILE n 
5 444  HIS n 
5 445  THR n 
5 446  MET n 
5 447  HIS n 
5 448  GLU n 
5 449  GLY n 
5 450  LYS n 
5 451  GLU n 
5 452  TYR n 
5 453  ILE n 
5 454  ILE n 
5 455  LEU n 
5 456  SER n 
5 457  ASN n 
5 458  ALA n 
5 459  GLY n 
5 460  GLY n 
5 461  PRO n 
5 462  LYS n 
5 463  ARG n 
5 464  GLU n 
5 465  ASN n 
5 466  GLY n 
5 467  MET n 
5 468  VAL n 
5 469  HIS n 
5 470  LEU n 
5 471  ALA n 
5 472  ARG n 
5 473  VAL n 
5 474  GLU n 
5 475  GLU n 
5 476  ASN n 
5 477  GLY n 
5 478  GLU n 
5 479  LEU n 
5 480  THR n 
5 481  TRP n 
5 482  LEU n 
5 483  LYS n 
5 484  HIS n 
5 485  ASN n 
5 486  PRO n 
5 487  ILE n 
5 488  GLN n 
5 489  LYS n 
5 490  GLY n 
5 491  GLU n 
5 492  PHE n 
5 493  ALA n 
5 494  TYR n 
5 495  ASN n 
5 496  SER n 
5 497  LEU n 
5 498  GLN n 
5 499  GLU n 
5 500  LEU n 
5 501  GLY n 
5 502  ASN n 
5 503  GLY n 
5 504  GLU n 
5 505  TYR n 
5 506  GLY n 
5 507  ILE n 
5 508  LEU n 
5 509  TYR n 
5 510  GLU n 
5 511  HIS n 
5 512  THR n 
5 513  GLU n 
5 514  LYS n 
5 515  GLY n 
5 516  GLN n 
5 517  ASN n 
5 518  ALA n 
5 519  TYR n 
5 520  THR n 
5 521  LEU n 
5 522  SER n 
5 523  PHE n 
5 524  ARG n 
5 525  LYS n 
5 526  PHE n 
5 527  ASN n 
5 528  TRP n 
5 529  GLU n 
5 530  PHE n 
5 531  LEU n 
5 532  SER n 
5 533  LYS n 
5 534  ASN n 
5 535  GLY n 
5 536  SER n 
5 537  GLY n 
5 538  SER n 
5 539  GLY n 
5 540  ILE n 
5 541  PRO n 
5 542  ILE n 
5 543  GLN n 
5 544  LEU n 
5 545  THR n 
5 546  VAL n 
5 547  PHE n 
5 548  PHE n 
5 549  MET n 
5 550  ILE n 
5 551  ILE n 
5 552  TYR n 
5 553  VAL n 
5 554  LEU n 
5 555  GLU n 
5 556  SER n 
5 557  LEU n 
5 558  THR n 
5 559  ILE n 
5 560  ILE n 
5 561  VAL n 
5 562  GLN n 
5 563  SER n 
5 564  SER n 
5 565  LEU n 
5 566  ILE n 
5 567  VAL n 
5 568  ALA n 
5 569  VAL n 
5 570  LEU n 
5 571  GLY n 
5 572  ARG n 
5 573  GLU n 
5 574  TRP n 
5 575  LEU n 
5 576  GLN n 
5 577  VAL n 
5 578  ARG n 
5 579  ARG n 
5 580  LEU n 
5 581  MET n 
5 582  PRO n 
5 583  VAL n 
5 584  ASP n 
5 585  MET n 
5 586  ILE n 
5 587  LEU n 
5 588  ILE n 
5 589  SER n 
5 590  LEU n 
5 591  GLY n 
5 592  ILE n 
5 593  SER n 
5 594  ARG n 
5 595  PHE n 
5 596  CYS n 
5 597  LEU n 
5 598  GLN n 
5 599  TRP n 
5 600  ALA n 
5 601  SER n 
5 602  MET n 
5 603  LEU n 
5 604  ASN n 
5 605  ASN n 
5 606  PHE n 
5 607  CYS n 
5 608  SER n 
5 609  TYR n 
5 610  PHE n 
5 611  ASN n 
5 612  LEU n 
5 613  ASN n 
5 614  TYR n 
5 615  VAL n 
5 616  LEU n 
5 617  CYS n 
5 618  ASN n 
5 619  LEU n 
5 620  THR n 
5 621  ILE n 
5 622  THR n 
5 623  TRP n 
5 624  GLU n 
5 625  PHE n 
5 626  PHE n 
5 627  ASN n 
5 628  ILE n 
5 629  LEU n 
5 630  THR n 
5 631  PHE n 
5 632  TRP n 
5 633  LEU n 
5 634  ASN n 
5 635  SER n 
5 636  LEU n 
5 637  LEU n 
5 638  THR n 
5 639  VAL n 
5 640  PHE n 
5 641  TYR n 
5 642  CYS n 
5 643  ILE n 
5 644  LYS n 
5 645  VAL n 
5 646  SER n 
5 647  SER n 
5 648  PHE n 
5 649  THR n 
5 650  HIS n 
5 651  HIS n 
5 652  ILE n 
5 653  PHE n 
5 654  LEU n 
5 655  TRP n 
5 656  LEU n 
5 657  ARG n 
5 658  TRP n 
5 659  ARG n 
5 660  ILE n 
5 661  LEU n 
5 662  ARG n 
5 663  LEU n 
5 664  PHE n 
5 665  PRO n 
5 666  TRP n 
5 667  ILE n 
5 668  LEU n 
5 669  LEU n 
5 670  GLY n 
5 671  CYS n 
5 672  LEU n 
5 673  MET n 
5 674  ILE n 
5 675  THR n 
5 676  CYS n 
5 677  VAL n 
5 678  THR n 
5 679  ILE n 
5 680  ILE n 
5 681  PRO n 
5 682  SER n 
5 683  ALA n 
5 684  ILE n 
5 685  GLY n 
5 686  ASN n 
5 687  TYR n 
5 688  ILE n 
5 689  GLN n 
5 690  ILE n 
5 691  GLN n 
5 692  LEU n 
5 693  LEU n 
5 694  THR n 
5 695  MET n 
5 696  GLU n 
5 697  HIS n 
5 698  LEU n 
5 699  PRO n 
5 700  ARG n 
5 701  ASN n 
5 702  SER n 
5 703  THR n 
5 704  VAL n 
5 705  THR n 
5 706  ASP n 
5 707  LYS n 
5 708  LEU n 
5 709  GLU n 
5 710  ASN n 
5 711  PHE n 
5 712  HIS n 
5 713  GLN n 
5 714  TYR n 
5 715  GLN n 
5 716  PHE n 
5 717  GLN n 
5 718  ALA n 
5 719  HIS n 
5 720  THR n 
5 721  VAL n 
5 722  ALA n 
5 723  LEU n 
5 724  VAL n 
5 725  ILE n 
5 726  PRO n 
5 727  PHE n 
5 728  ILE n 
5 729  LEU n 
5 730  PHE n 
5 731  LEU n 
5 732  ALA n 
5 733  SER n 
5 734  THR n 
5 735  ILE n 
5 736  PHE n 
5 737  LEU n 
5 738  MET n 
5 739  ALA n 
5 740  SER n 
5 741  LEU n 
5 742  THR n 
5 743  LYS n 
5 744  GLN n 
5 745  ILE n 
5 746  GLN n 
5 747  HIS n 
5 748  HIS n 
5 749  SER n 
5 750  THR n 
5 751  GLY n 
5 752  HIS n 
5 753  CYS n 
5 754  ASN n 
5 755  PRO n 
5 756  SER n 
5 757  MET n 
5 758  LYS n 
5 759  ALA n 
5 760  ARG n 
5 761  PHE n 
5 762  THR n 
5 763  ALA n 
5 764  LEU n 
5 765  ARG n 
5 766  SER n 
5 767  LEU n 
5 768  ALA n 
5 769  VAL n 
5 770  LEU n 
5 771  PHE n 
5 772  ILE n 
5 773  VAL n 
5 774  PHE n 
5 775  THR n 
5 776  SER n 
5 777  TYR n 
5 778  PHE n 
5 779  LEU n 
5 780  THR n 
5 781  ILE n 
5 782  LEU n 
5 783  ILE n 
5 784  THR n 
5 785  ILE n 
5 786  ILE n 
5 787  GLY n 
5 788  THR n 
5 789  LEU n 
5 790  PHE n 
5 791  ASP n 
5 792  LYS n 
5 793  ARG n 
5 794  CYS n 
5 795  TRP n 
5 796  LEU n 
5 797  TRP n 
5 798  VAL n 
5 799  TRP n 
5 800  GLU n 
5 801  ALA n 
5 802  PHE n 
5 803  VAL n 
5 804  TYR n 
5 805  ALA n 
5 806  PHE n 
5 807  ILE n 
5 808  LEU n 
5 809  MET n 
5 810  HIS n 
5 811  SER n 
5 812  THR n 
5 813  SER n 
5 814  LEU n 
5 815  MET n 
5 816  LEU n 
5 817  SER n 
5 818  SER n 
5 819  PRO n 
5 820  THR n 
5 821  LEU n 
5 822  LYS n 
5 823  ARG n 
5 824  ILE n 
5 825  LEU n 
5 826  LYS n 
5 827  GLY n 
5 828  LYS n 
5 829  CYS n 
5 830  GLY n 
5 831  SER n 
5 832  GLY n 
5 833  SER n 
5 834  GLY n 
5 835  GLY n 
5 836  SER n 
5 837  GLY n 
5 838  SER n 
5 839  GLY n 
5 840  GLY n 
5 841  SER n 
5 842  GLY n 
5 843  SER n 
5 844  GLY n 
5 845  GLY n 
5 846  SER n 
5 847  GLY n 
5 848  SER n 
5 849  GLY n 
5 850  SER n 
5 851  SER n 
5 852  GLY n 
5 853  GLY n 
5 854  VAL n 
5 855  PHE n 
5 856  THR n 
5 857  LEU n 
5 858  GLU n 
5 859  ASP n 
5 860  PHE n 
5 861  VAL n 
5 862  GLY n 
5 863  ASP n 
5 864  TRP n 
5 865  GLU n 
5 866  GLN n 
5 867  THR n 
5 868  ALA n 
5 869  ALA n 
5 870  TYR n 
5 871  ASN n 
5 872  LEU n 
5 873  ASP n 
5 874  GLN n 
5 875  VAL n 
5 876  LEU n 
5 877  GLU n 
5 878  GLN n 
5 879  GLY n 
5 880  GLY n 
5 881  VAL n 
5 882  SER n 
5 883  SER n 
5 884  LEU n 
5 885  LEU n 
5 886  GLN n 
5 887  ASN n 
5 888  LEU n 
5 889  ALA n 
5 890  VAL n 
5 891  SER n 
5 892  VAL n 
5 893  THR n 
5 894  PRO n 
5 895  ILE n 
5 896  GLN n 
5 897  ARG n 
5 898  ILE n 
5 899  VAL n 
5 900  ARG n 
5 901  SER n 
5 902  GLY n 
5 903  GLU n 
5 904  ASN n 
5 905  ALA n 
5 906  LEU n 
5 907  LYS n 
5 908  ILE n 
5 909  ASP n 
5 910  ILE n 
5 911  HIS n 
5 912  VAL n 
5 913  ILE n 
5 914  ILE n 
5 915  PRO n 
5 916  TYR n 
5 917  GLU n 
5 918  GLY n 
5 919  LEU n 
5 920  SER n 
5 921  ALA n 
5 922  ASP n 
5 923  GLN n 
5 924  MET n 
5 925  ALA n 
5 926  GLN n 
5 927  ILE n 
5 928  GLU n 
5 929  GLU n 
5 930  VAL n 
5 931  PHE n 
5 932  LYS n 
5 933  VAL n 
5 934  VAL n 
5 935  TYR n 
5 936  PRO n 
5 937  VAL n 
5 938  ASP n 
5 939  ASP n 
5 940  HIS n 
5 941  HIS n 
5 942  PHE n 
5 943  LYS n 
5 944  VAL n 
5 945  ILE n 
5 946  LEU n 
5 947  PRO n 
5 948  TYR n 
5 949  GLY n 
5 950  THR n 
5 951  LEU n 
5 952  VAL n 
5 953  ILE n 
5 954  ASP n 
5 955  GLY n 
5 956  VAL n 
5 957  THR n 
5 958  PRO n 
5 959  ASN n 
5 960  MET n 
5 961  LEU n 
5 962  ASN n 
5 963  TYR n 
5 964  PHE n 
5 965  GLY n 
5 966  ARG n 
5 967  PRO n 
5 968  TYR n 
5 969  GLU n 
5 970  GLY n 
5 971  ILE n 
5 972  ALA n 
5 973  VAL n 
5 974  PHE n 
5 975  ASP n 
5 976  GLY n 
5 977  LYS n 
5 978  LYS n 
5 979  ILE n 
5 980  THR n 
5 981  VAL n 
5 982  THR n 
5 983  GLY n 
5 984  THR n 
5 985  LEU n 
5 986  TRP n 
5 987  ASN n 
5 988  GLY n 
5 989  ASN n 
5 990  LYS n 
5 991  ILE n 
5 992  ILE n 
5 993  ASP n 
5 994  GLU n 
5 995  ARG n 
5 996  LEU n 
5 997  ILE n 
5 998  THR n 
5 999  PRO n 
5 1000 ASP n 
5 1001 GLY n 
5 1002 SER n 
5 1003 MET n 
5 1004 LEU n 
5 1005 PHE n 
5 1006 ARG n 
5 1007 VAL n 
5 1008 THR n 
5 1009 ILE n 
5 1010 ASN n 
5 1011 SER n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   355  human ? 'GNAI2, GNAI2B'              ? ? ? ? ? ? 'Homo sapiens'             9606  ? ? ? 
? ? ? ? ? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1   366  human ? GNB1                         ? ? ? ? ? ? 'Homo sapiens'             9606  ? ? ? 
? ? ? ? ? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1   71   human ? GNG2                         ? ? ? ? ? ? 'Homo sapiens'             9606  ? ? ? 
? ? ? ? ? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1   266  ?     ? ?                            ? ? ? ? ? ? 'Homo sapiens'             9606  ? ? ? 
? ? ? ? ? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1   534  ?     ? 'nanA_2, SAMEA3353537_00427' ? ? ? ? ? ? 'Streptococcus pneumoniae' 1313  ? ? ? 
? ? ? ? ? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 2 sample 'Biological sequence' 535 829  human ? TAS2R16                      ? ? ? ? ? ? 'Homo sapiens'             9606  ? ? ? 
? ? ? ? ? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 3 sample 'Biological sequence' 830 1011 ?     ? ?                            ? ? ? ? ? ? 'synthetic construct'      32630 ? ? ? 
? ? ? ? ? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                          ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                                         ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                                       ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                  ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                                         ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                                        ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                  ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                          ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                                        ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE                                       ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                                          ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                           ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                                       ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                    ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                                          ? 'C5 H9 N O2'     115.130 
SA0 D-saccharide        n '2-(hydroxymethyl)phenyl beta-D-glucopyranoside' 
'Salicin; 2-(hydroxymethyl)phenyl beta-D-glucoside; 2-(hydroxymethyl)phenyl D-glucoside; 2-(hydroxymethyl)phenyl glucoside' 
'C13 H18 O7'     286.278 
SER 'L-peptide linking' y SERINE                                           ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                                        ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                       ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                         ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                           ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1    MET 1    1    ?   ?   ?   A . n 
A 1 2    GLY 2    2    ?   ?   ?   A . n 
A 1 3    CYS 3    3    ?   ?   ?   A . n 
A 1 4    THR 4    4    4   THR THR A . n 
A 1 5    VAL 5    5    5   VAL VAL A . n 
A 1 6    SER 6    6    6   SER SER A . n 
A 1 7    ALA 7    7    7   ALA ALA A . n 
A 1 8    GLU 8    8    8   GLU GLU A . n 
A 1 9    ASP 9    9    9   ASP ASP A . n 
A 1 10   LYS 10   10   10  LYS LYS A . n 
A 1 11   ALA 11   11   11  ALA ALA A . n 
A 1 12   ALA 12   12   12  ALA ALA A . n 
A 1 13   ALA 13   13   13  ALA ALA A . n 
A 1 14   GLU 14   14   14  GLU GLU A . n 
A 1 15   ARG 15   15   15  ARG ARG A . n 
A 1 16   SER 16   16   16  SER SER A . n 
A 1 17   LYS 17   17   17  LYS LYS A . n 
A 1 18   MET 18   18   18  MET MET A . n 
A 1 19   ILE 19   19   19  ILE ILE A . n 
A 1 20   ASP 20   20   20  ASP ASP A . n 
A 1 21   LYS 21   21   21  LYS LYS A . n 
A 1 22   ASN 22   22   22  ASN ASN A . n 
A 1 23   LEU 23   23   23  LEU LEU A . n 
A 1 24   ARG 24   24   24  ARG ARG A . n 
A 1 25   GLU 25   25   25  GLU GLU A . n 
A 1 26   ASP 26   26   26  ASP ASP A . n 
A 1 27   GLY 27   27   27  GLY GLY A . n 
A 1 28   GLU 28   28   28  GLU GLU A . n 
A 1 29   LYS 29   29   29  LYS LYS A . n 
A 1 30   ALA 30   30   30  ALA ALA A . n 
A 1 31   ALA 31   31   31  ALA ALA A . n 
A 1 32   ARG 32   32   32  ARG ARG A . n 
A 1 33   GLU 33   33   33  GLU GLU A . n 
A 1 34   VAL 34   34   34  VAL VAL A . n 
A 1 35   LYS 35   35   35  LYS LYS A . n 
A 1 36   LEU 36   36   36  LEU LEU A . n 
A 1 37   LEU 37   37   37  LEU LEU A . n 
A 1 38   LEU 38   38   38  LEU LEU A . n 
A 1 39   LEU 39   39   39  LEU LEU A . n 
A 1 40   GLY 40   40   40  GLY GLY A . n 
A 1 41   ALA 41   41   41  ALA ALA A . n 
A 1 42   GLY 42   42   42  GLY GLY A . n 
A 1 43   GLU 43   43   43  GLU GLU A . n 
A 1 44   SER 44   44   44  SER SER A . n 
A 1 45   GLY 45   45   45  GLY GLY A . n 
A 1 46   LYS 46   46   46  LYS LYS A . n 
A 1 47   ASN 47   47   47  ASN ASN A . n 
A 1 48   THR 48   48   48  THR THR A . n 
A 1 49   ILE 49   49   49  ILE ILE A . n 
A 1 50   VAL 50   50   50  VAL VAL A . n 
A 1 51   LYS 51   51   51  LYS LYS A . n 
A 1 52   GLN 52   52   52  GLN GLN A . n 
A 1 53   MET 53   53   53  MET MET A . n 
A 1 54   LYS 54   54   54  LYS LYS A . n 
A 1 55   ILE 55   55   55  ILE ILE A . n 
A 1 56   ILE 56   56   56  ILE ILE A . n 
A 1 57   HIS 57   57   ?   ?   ?   A . n 
A 1 58   GLU 58   58   ?   ?   ?   A . n 
A 1 59   ASP 59   59   ?   ?   ?   A . n 
A 1 60   GLY 60   60   ?   ?   ?   A . n 
A 1 61   TYR 61   61   ?   ?   ?   A . n 
A 1 62   SER 62   62   ?   ?   ?   A . n 
A 1 63   GLU 63   63   ?   ?   ?   A . n 
A 1 64   GLU 64   64   ?   ?   ?   A . n 
A 1 65   GLU 65   65   ?   ?   ?   A . n 
A 1 66   CYS 66   66   ?   ?   ?   A . n 
A 1 67   ARG 67   67   ?   ?   ?   A . n 
A 1 68   GLN 68   68   ?   ?   ?   A . n 
A 1 69   TYR 69   69   ?   ?   ?   A . n 
A 1 70   ARG 70   70   ?   ?   ?   A . n 
A 1 71   ALA 71   71   ?   ?   ?   A . n 
A 1 72   VAL 72   72   ?   ?   ?   A . n 
A 1 73   VAL 73   73   ?   ?   ?   A . n 
A 1 74   TYR 74   74   ?   ?   ?   A . n 
A 1 75   SER 75   75   ?   ?   ?   A . n 
A 1 76   ASN 76   76   ?   ?   ?   A . n 
A 1 77   THR 77   77   ?   ?   ?   A . n 
A 1 78   ILE 78   78   ?   ?   ?   A . n 
A 1 79   GLN 79   79   ?   ?   ?   A . n 
A 1 80   SER 80   80   ?   ?   ?   A . n 
A 1 81   ILE 81   81   ?   ?   ?   A . n 
A 1 82   MET 82   82   ?   ?   ?   A . n 
A 1 83   ALA 83   83   ?   ?   ?   A . n 
A 1 84   ILE 84   84   ?   ?   ?   A . n 
A 1 85   VAL 85   85   ?   ?   ?   A . n 
A 1 86   LYS 86   86   ?   ?   ?   A . n 
A 1 87   ALA 87   87   ?   ?   ?   A . n 
A 1 88   MET 88   88   ?   ?   ?   A . n 
A 1 89   GLY 89   89   ?   ?   ?   A . n 
A 1 90   ASN 90   90   ?   ?   ?   A . n 
A 1 91   LEU 91   91   ?   ?   ?   A . n 
A 1 92   GLN 92   92   ?   ?   ?   A . n 
A 1 93   ILE 93   93   ?   ?   ?   A . n 
A 1 94   ASP 94   94   ?   ?   ?   A . n 
A 1 95   PHE 95   95   ?   ?   ?   A . n 
A 1 96   ALA 96   96   ?   ?   ?   A . n 
A 1 97   ASP 97   97   ?   ?   ?   A . n 
A 1 98   PRO 98   98   ?   ?   ?   A . n 
A 1 99   SER 99   99   ?   ?   ?   A . n 
A 1 100  ARG 100  100  ?   ?   ?   A . n 
A 1 101  ALA 101  101  ?   ?   ?   A . n 
A 1 102  ASP 102  102  ?   ?   ?   A . n 
A 1 103  ASP 103  103  ?   ?   ?   A . n 
A 1 104  ALA 104  104  ?   ?   ?   A . n 
A 1 105  ARG 105  105  ?   ?   ?   A . n 
A 1 106  GLN 106  106  ?   ?   ?   A . n 
A 1 107  LEU 107  107  ?   ?   ?   A . n 
A 1 108  PHE 108  108  ?   ?   ?   A . n 
A 1 109  ALA 109  109  ?   ?   ?   A . n 
A 1 110  LEU 110  110  ?   ?   ?   A . n 
A 1 111  SER 111  111  ?   ?   ?   A . n 
A 1 112  CYS 112  112  ?   ?   ?   A . n 
A 1 113  THR 113  113  ?   ?   ?   A . n 
A 1 114  ALA 114  114  ?   ?   ?   A . n 
A 1 115  GLU 115  115  ?   ?   ?   A . n 
A 1 116  GLU 116  116  ?   ?   ?   A . n 
A 1 117  GLN 117  117  ?   ?   ?   A . n 
A 1 118  GLY 118  118  ?   ?   ?   A . n 
A 1 119  VAL 119  119  ?   ?   ?   A . n 
A 1 120  LEU 120  120  ?   ?   ?   A . n 
A 1 121  PRO 121  121  ?   ?   ?   A . n 
A 1 122  ASP 122  122  ?   ?   ?   A . n 
A 1 123  ASP 123  123  ?   ?   ?   A . n 
A 1 124  LEU 124  124  ?   ?   ?   A . n 
A 1 125  SER 125  125  ?   ?   ?   A . n 
A 1 126  GLY 126  126  ?   ?   ?   A . n 
A 1 127  VAL 127  127  ?   ?   ?   A . n 
A 1 128  ILE 128  128  ?   ?   ?   A . n 
A 1 129  ARG 129  129  ?   ?   ?   A . n 
A 1 130  ARG 130  130  ?   ?   ?   A . n 
A 1 131  LEU 131  131  ?   ?   ?   A . n 
A 1 132  TRP 132  132  ?   ?   ?   A . n 
A 1 133  ALA 133  133  ?   ?   ?   A . n 
A 1 134  ASP 134  134  ?   ?   ?   A . n 
A 1 135  HIS 135  135  ?   ?   ?   A . n 
A 1 136  GLY 136  136  ?   ?   ?   A . n 
A 1 137  VAL 137  137  ?   ?   ?   A . n 
A 1 138  GLN 138  138  ?   ?   ?   A . n 
A 1 139  ALA 139  139  ?   ?   ?   A . n 
A 1 140  CYS 140  140  ?   ?   ?   A . n 
A 1 141  PHE 141  141  ?   ?   ?   A . n 
A 1 142  GLY 142  142  ?   ?   ?   A . n 
A 1 143  ARG 143  143  ?   ?   ?   A . n 
A 1 144  SER 144  144  ?   ?   ?   A . n 
A 1 145  ARG 145  145  ?   ?   ?   A . n 
A 1 146  GLU 146  146  ?   ?   ?   A . n 
A 1 147  TYR 147  147  ?   ?   ?   A . n 
A 1 148  GLN 148  148  ?   ?   ?   A . n 
A 1 149  LEU 149  149  ?   ?   ?   A . n 
A 1 150  ASN 150  150  ?   ?   ?   A . n 
A 1 151  ASP 151  151  ?   ?   ?   A . n 
A 1 152  SER 152  152  ?   ?   ?   A . n 
A 1 153  ALA 153  153  ?   ?   ?   A . n 
A 1 154  ALA 154  154  ?   ?   ?   A . n 
A 1 155  TYR 155  155  ?   ?   ?   A . n 
A 1 156  TYR 156  156  ?   ?   ?   A . n 
A 1 157  LEU 157  157  ?   ?   ?   A . n 
A 1 158  ASN 158  158  ?   ?   ?   A . n 
A 1 159  ASP 159  159  ?   ?   ?   A . n 
A 1 160  LEU 160  160  ?   ?   ?   A . n 
A 1 161  GLU 161  161  ?   ?   ?   A . n 
A 1 162  ARG 162  162  ?   ?   ?   A . n 
A 1 163  ILE 163  163  ?   ?   ?   A . n 
A 1 164  ALA 164  164  ?   ?   ?   A . n 
A 1 165  GLN 165  165  ?   ?   ?   A . n 
A 1 166  SER 166  166  ?   ?   ?   A . n 
A 1 167  ASP 167  167  ?   ?   ?   A . n 
A 1 168  TYR 168  168  ?   ?   ?   A . n 
A 1 169  ILE 169  169  ?   ?   ?   A . n 
A 1 170  PRO 170  170  ?   ?   ?   A . n 
A 1 171  THR 171  171  ?   ?   ?   A . n 
A 1 172  GLN 172  172  ?   ?   ?   A . n 
A 1 173  GLN 173  173  ?   ?   ?   A . n 
A 1 174  ASP 174  174  ?   ?   ?   A . n 
A 1 175  VAL 175  175  ?   ?   ?   A . n 
A 1 176  LEU 176  176  ?   ?   ?   A . n 
A 1 177  ARG 177  177  ?   ?   ?   A . n 
A 1 178  THR 178  178  ?   ?   ?   A . n 
A 1 179  ARG 179  179  ?   ?   ?   A . n 
A 1 180  VAL 180  180  ?   ?   ?   A . n 
A 1 181  LYS 181  181  ?   ?   ?   A . n 
A 1 182  THR 182  182  ?   ?   ?   A . n 
A 1 183  THR 183  183  183 THR THR A . n 
A 1 184  GLY 184  184  184 GLY GLY A . n 
A 1 185  ILE 185  185  185 ILE ILE A . n 
A 1 186  VAL 186  186  186 VAL VAL A . n 
A 1 187  GLU 187  187  187 GLU GLU A . n 
A 1 188  THR 188  188  188 THR THR A . n 
A 1 189  HIS 189  189  189 HIS HIS A . n 
A 1 190  PHE 190  190  190 PHE PHE A . n 
A 1 191  THR 191  191  191 THR THR A . n 
A 1 192  PHE 192  192  192 PHE PHE A . n 
A 1 193  LYS 193  193  193 LYS LYS A . n 
A 1 194  ASP 194  194  194 ASP ASP A . n 
A 1 195  LEU 195  195  195 LEU LEU A . n 
A 1 196  HIS 196  196  196 HIS HIS A . n 
A 1 197  PHE 197  197  197 PHE PHE A . n 
A 1 198  LYS 198  198  198 LYS LYS A . n 
A 1 199  MET 199  199  199 MET MET A . n 
A 1 200  PHE 200  200  200 PHE PHE A . n 
A 1 201  ASP 201  201  201 ASP ASP A . n 
A 1 202  VAL 202  202  202 VAL VAL A . n 
A 1 203  GLY 203  203  203 GLY GLY A . n 
A 1 204  ALA 204  204  204 ALA ALA A . n 
A 1 205  GLN 205  205  205 GLN GLN A . n 
A 1 206  ARG 206  206  206 ARG ARG A . n 
A 1 207  SER 207  207  207 SER SER A . n 
A 1 208  GLU 208  208  208 GLU GLU A . n 
A 1 209  ARG 209  209  209 ARG ARG A . n 
A 1 210  LYS 210  210  210 LYS LYS A . n 
A 1 211  LYS 211  211  211 LYS LYS A . n 
A 1 212  TRP 212  212  212 TRP TRP A . n 
A 1 213  ILE 213  213  213 ILE ILE A . n 
A 1 214  HIS 214  214  214 HIS HIS A . n 
A 1 215  CYS 215  215  215 CYS CYS A . n 
A 1 216  PHE 216  216  216 PHE PHE A . n 
A 1 217  GLU 217  217  217 GLU GLU A . n 
A 1 218  GLY 218  218  218 GLY GLY A . n 
A 1 219  VAL 219  219  219 VAL VAL A . n 
A 1 220  THR 220  220  220 THR THR A . n 
A 1 221  ALA 221  221  221 ALA ALA A . n 
A 1 222  ILE 222  222  222 ILE ILE A . n 
A 1 223  ILE 223  223  223 ILE ILE A . n 
A 1 224  PHE 224  224  224 PHE PHE A . n 
A 1 225  CYS 225  225  225 CYS CYS A . n 
A 1 226  VAL 226  226  226 VAL VAL A . n 
A 1 227  ALA 227  227  227 ALA ALA A . n 
A 1 228  LEU 228  228  228 LEU LEU A . n 
A 1 229  SER 229  229  229 SER SER A . n 
A 1 230  ALA 230  230  230 ALA ALA A . n 
A 1 231  TYR 231  231  231 TYR TYR A . n 
A 1 232  ASP 232  232  232 ASP ASP A . n 
A 1 233  LEU 233  233  233 LEU LEU A . n 
A 1 234  VAL 234  234  234 VAL VAL A . n 
A 1 235  LEU 235  235  235 LEU LEU A . n 
A 1 236  ALA 236  236  236 ALA ALA A . n 
A 1 237  GLU 237  237  237 GLU GLU A . n 
A 1 238  ASP 238  238  238 ASP ASP A . n 
A 1 239  GLU 239  239  239 GLU GLU A . n 
A 1 240  GLU 240  240  240 GLU GLU A . n 
A 1 241  MET 241  241  241 MET MET A . n 
A 1 242  ASN 242  242  242 ASN ASN A . n 
A 1 243  ARG 243  243  243 ARG ARG A . n 
A 1 244  MET 244  244  244 MET MET A . n 
A 1 245  HIS 245  245  245 HIS HIS A . n 
A 1 246  GLU 246  246  246 GLU GLU A . n 
A 1 247  SER 247  247  247 SER SER A . n 
A 1 248  MET 248  248  248 MET MET A . n 
A 1 249  LYS 249  249  249 LYS LYS A . n 
A 1 250  LEU 250  250  250 LEU LEU A . n 
A 1 251  PHE 251  251  251 PHE PHE A . n 
A 1 252  ASP 252  252  252 ASP ASP A . n 
A 1 253  SER 253  253  253 SER SER A . n 
A 1 254  ILE 254  254  254 ILE ILE A . n 
A 1 255  CYS 255  255  255 CYS CYS A . n 
A 1 256  ASN 256  256  256 ASN ASN A . n 
A 1 257  ASN 257  257  257 ASN ASN A . n 
A 1 258  LYS 258  258  258 LYS LYS A . n 
A 1 259  TRP 259  259  259 TRP TRP A . n 
A 1 260  PHE 260  260  260 PHE PHE A . n 
A 1 261  THR 261  261  261 THR THR A . n 
A 1 262  ASP 262  262  262 ASP ASP A . n 
A 1 263  THR 263  263  263 THR THR A . n 
A 1 264  SER 264  264  264 SER SER A . n 
A 1 265  ILE 265  265  265 ILE ILE A . n 
A 1 266  ILE 266  266  266 ILE ILE A . n 
A 1 267  LEU 267  267  267 LEU LEU A . n 
A 1 268  PHE 268  268  268 PHE PHE A . n 
A 1 269  LEU 269  269  269 LEU LEU A . n 
A 1 270  ASN 270  270  270 ASN ASN A . n 
A 1 271  LYS 271  271  271 LYS LYS A . n 
A 1 272  LYS 272  272  272 LYS LYS A . n 
A 1 273  ASP 273  273  273 ASP ASP A . n 
A 1 274  LEU 274  274  274 LEU LEU A . n 
A 1 275  PHE 275  275  275 PHE PHE A . n 
A 1 276  GLU 276  276  276 GLU GLU A . n 
A 1 277  GLU 277  277  277 GLU GLU A . n 
A 1 278  LYS 278  278  278 LYS LYS A . n 
A 1 279  ILE 279  279  279 ILE ILE A . n 
A 1 280  THR 280  280  280 THR THR A . n 
A 1 281  HIS 281  281  281 HIS HIS A . n 
A 1 282  SER 282  282  282 SER SER A . n 
A 1 283  PRO 283  283  283 PRO PRO A . n 
A 1 284  LEU 284  284  284 LEU LEU A . n 
A 1 285  THR 285  285  285 THR THR A . n 
A 1 286  ILE 286  286  286 ILE ILE A . n 
A 1 287  CYS 287  287  287 CYS CYS A . n 
A 1 288  PHE 288  288  288 PHE PHE A . n 
A 1 289  PRO 289  289  289 PRO PRO A . n 
A 1 290  GLU 290  290  290 GLU GLU A . n 
A 1 291  TYR 291  291  291 TYR TYR A . n 
A 1 292  THR 292  292  292 THR THR A . n 
A 1 293  GLY 293  293  293 GLY GLY A . n 
A 1 294  ALA 294  294  294 ALA ALA A . n 
A 1 295  ASN 295  295  295 ASN ASN A . n 
A 1 296  LYS 296  296  296 LYS LYS A . n 
A 1 297  TYR 297  297  297 TYR TYR A . n 
A 1 298  ASP 298  298  298 ASP ASP A . n 
A 1 299  GLU 299  299  299 GLU GLU A . n 
A 1 300  ALA 300  300  300 ALA ALA A . n 
A 1 301  ALA 301  301  301 ALA ALA A . n 
A 1 302  SER 302  302  302 SER SER A . n 
A 1 303  TYR 303  303  303 TYR TYR A . n 
A 1 304  ILE 304  304  304 ILE ILE A . n 
A 1 305  GLN 305  305  305 GLN GLN A . n 
A 1 306  SER 306  306  306 SER SER A . n 
A 1 307  LYS 307  307  307 LYS LYS A . n 
A 1 308  PHE 308  308  308 PHE PHE A . n 
A 1 309  GLU 309  309  309 GLU GLU A . n 
A 1 310  ASP 310  310  310 ASP ASP A . n 
A 1 311  LEU 311  311  311 LEU LEU A . n 
A 1 312  ASN 312  312  312 ASN ASN A . n 
A 1 313  LYS 313  313  313 LYS LYS A . n 
A 1 314  ARG 314  314  314 ARG ARG A . n 
A 1 315  LYS 315  315  315 LYS LYS A . n 
A 1 316  ASP 316  316  316 ASP ASP A . n 
A 1 317  THR 317  317  317 THR THR A . n 
A 1 318  LYS 318  318  318 LYS LYS A . n 
A 1 319  GLU 319  319  319 GLU GLU A . n 
A 1 320  ILE 320  320  320 ILE ILE A . n 
A 1 321  TYR 321  321  321 TYR TYR A . n 
A 1 322  THR 322  322  322 THR THR A . n 
A 1 323  HIS 323  323  323 HIS HIS A . n 
A 1 324  PHE 324  324  324 PHE PHE A . n 
A 1 325  THR 325  325  325 THR THR A . n 
A 1 326  CYS 326  326  326 CYS CYS A . n 
A 1 327  SER 327  327  327 SER SER A . n 
A 1 328  THR 328  328  328 THR THR A . n 
A 1 329  ASP 329  329  329 ASP ASP A . n 
A 1 330  THR 330  330  330 THR THR A . n 
A 1 331  LYS 331  331  331 LYS LYS A . n 
A 1 332  ASN 332  332  332 ASN ASN A . n 
A 1 333  VAL 333  333  333 VAL VAL A . n 
A 1 334  GLN 334  334  334 GLN GLN A . n 
A 1 335  PHE 335  335  335 PHE PHE A . n 
A 1 336  VAL 336  336  336 VAL VAL A . n 
A 1 337  PHE 337  337  337 PHE PHE A . n 
A 1 338  ASP 338  338  338 ASP ASP A . n 
A 1 339  ALA 339  339  339 ALA ALA A . n 
A 1 340  VAL 340  340  340 VAL VAL A . n 
A 1 341  THR 341  341  341 THR THR A . n 
A 1 342  ASP 342  342  342 ASP ASP A . n 
A 1 343  VAL 343  343  343 VAL VAL A . n 
A 1 344  ILE 344  344  344 ILE ILE A . n 
A 1 345  ILE 345  345  345 ILE ILE A . n 
A 1 346  LYS 346  346  346 LYS LYS A . n 
A 1 347  ASN 347  347  347 ASN ASN A . n 
A 1 348  ASN 348  348  348 ASN ASN A . n 
A 1 349  LEU 349  349  349 LEU LEU A . n 
A 1 350  LYS 350  350  350 LYS LYS A . n 
A 1 351  ASP 351  351  351 ASP ASP A . n 
A 1 352  CYS 352  352  352 CYS CYS A . n 
A 1 353  GLY 353  353  353 GLY GLY A . n 
A 1 354  LEU 354  354  354 LEU LEU A . n 
A 1 355  PHE 355  355  355 PHE PHE A . n 
B 2 1    MET 1    1    ?   ?   ?   B . n 
B 2 2    SER 2    2    ?   ?   ?   B . n 
B 2 3    GLU 3    3    3   GLU GLU B . n 
B 2 4    LEU 4    4    4   LEU LEU B . n 
B 2 5    ASP 5    5    5   ASP ASP B . n 
B 2 6    GLN 6    6    6   GLN GLN B . n 
B 2 7    LEU 7    7    7   LEU LEU B . n 
B 2 8    ARG 8    8    8   ARG ARG B . n 
B 2 9    GLN 9    9    9   GLN GLN B . n 
B 2 10   GLU 10   10   10  GLU GLU B . n 
B 2 11   ALA 11   11   11  ALA ALA B . n 
B 2 12   GLU 12   12   12  GLU GLU B . n 
B 2 13   GLN 13   13   13  GLN GLN B . n 
B 2 14   LEU 14   14   14  LEU LEU B . n 
B 2 15   LYS 15   15   15  LYS LYS B . n 
B 2 16   ASN 16   16   16  ASN ASN B . n 
B 2 17   GLN 17   17   17  GLN GLN B . n 
B 2 18   ILE 18   18   18  ILE ILE B . n 
B 2 19   ARG 19   19   19  ARG ARG B . n 
B 2 20   ASP 20   20   20  ASP ASP B . n 
B 2 21   ALA 21   21   21  ALA ALA B . n 
B 2 22   ARG 22   22   22  ARG ARG B . n 
B 2 23   LYS 23   23   23  LYS LYS B . n 
B 2 24   ALA 24   24   24  ALA ALA B . n 
B 2 25   CYS 25   25   25  CYS CYS B . n 
B 2 26   ALA 26   26   26  ALA ALA B . n 
B 2 27   ASP 27   27   27  ASP ASP B . n 
B 2 28   ALA 28   28   28  ALA ALA B . n 
B 2 29   THR 29   29   29  THR THR B . n 
B 2 30   LEU 30   30   30  LEU LEU B . n 
B 2 31   SER 31   31   31  SER SER B . n 
B 2 32   GLN 32   32   32  GLN GLN B . n 
B 2 33   ILE 33   33   33  ILE ILE B . n 
B 2 34   THR 34   34   34  THR THR B . n 
B 2 35   ASN 35   35   35  ASN ASN B . n 
B 2 36   ASN 36   36   36  ASN ASN B . n 
B 2 37   ILE 37   37   37  ILE ILE B . n 
B 2 38   ASP 38   38   38  ASP ASP B . n 
B 2 39   PRO 39   39   39  PRO PRO B . n 
B 2 40   VAL 40   40   40  VAL VAL B . n 
B 2 41   GLY 41   41   41  GLY GLY B . n 
B 2 42   ARG 42   42   42  ARG ARG B . n 
B 2 43   ILE 43   43   43  ILE ILE B . n 
B 2 44   GLN 44   44   44  GLN GLN B . n 
B 2 45   MET 45   45   45  MET MET B . n 
B 2 46   ARG 46   46   46  ARG ARG B . n 
B 2 47   THR 47   47   47  THR THR B . n 
B 2 48   ARG 48   48   48  ARG ARG B . n 
B 2 49   ARG 49   49   49  ARG ARG B . n 
B 2 50   THR 50   50   50  THR THR B . n 
B 2 51   LEU 51   51   51  LEU LEU B . n 
B 2 52   ARG 52   52   52  ARG ARG B . n 
B 2 53   GLY 53   53   53  GLY GLY B . n 
B 2 54   HIS 54   54   54  HIS HIS B . n 
B 2 55   LEU 55   55   55  LEU LEU B . n 
B 2 56   ALA 56   56   56  ALA ALA B . n 
B 2 57   LYS 57   57   57  LYS LYS B . n 
B 2 58   ILE 58   58   58  ILE ILE B . n 
B 2 59   TYR 59   59   59  TYR TYR B . n 
B 2 60   ALA 60   60   60  ALA ALA B . n 
B 2 61   MET 61   61   61  MET MET B . n 
B 2 62   HIS 62   62   62  HIS HIS B . n 
B 2 63   TRP 63   63   63  TRP TRP B . n 
B 2 64   GLY 64   64   64  GLY GLY B . n 
B 2 65   THR 65   65   65  THR THR B . n 
B 2 66   ASP 66   66   66  ASP ASP B . n 
B 2 67   SER 67   67   67  SER SER B . n 
B 2 68   ARG 68   68   68  ARG ARG B . n 
B 2 69   LEU 69   69   69  LEU LEU B . n 
B 2 70   LEU 70   70   70  LEU LEU B . n 
B 2 71   VAL 71   71   71  VAL VAL B . n 
B 2 72   SER 72   72   72  SER SER B . n 
B 2 73   ALA 73   73   73  ALA ALA B . n 
B 2 74   SER 74   74   74  SER SER B . n 
B 2 75   GLN 75   75   75  GLN GLN B . n 
B 2 76   ASP 76   76   76  ASP ASP B . n 
B 2 77   GLY 77   77   77  GLY GLY B . n 
B 2 78   LYS 78   78   78  LYS LYS B . n 
B 2 79   LEU 79   79   79  LEU LEU B . n 
B 2 80   ILE 80   80   80  ILE ILE B . n 
B 2 81   ILE 81   81   81  ILE ILE B . n 
B 2 82   TRP 82   82   82  TRP TRP B . n 
B 2 83   ASP 83   83   83  ASP ASP B . n 
B 2 84   SER 84   84   84  SER SER B . n 
B 2 85   TYR 85   85   85  TYR TYR B . n 
B 2 86   THR 86   86   86  THR THR B . n 
B 2 87   THR 87   87   87  THR THR B . n 
B 2 88   ASN 88   88   88  ASN ASN B . n 
B 2 89   LYS 89   89   89  LYS LYS B . n 
B 2 90   VAL 90   90   90  VAL VAL B . n 
B 2 91   HIS 91   91   91  HIS HIS B . n 
B 2 92   ALA 92   92   92  ALA ALA B . n 
B 2 93   ILE 93   93   93  ILE ILE B . n 
B 2 94   PRO 94   94   94  PRO PRO B . n 
B 2 95   LEU 95   95   95  LEU LEU B . n 
B 2 96   ARG 96   96   96  ARG ARG B . n 
B 2 97   SER 97   97   97  SER SER B . n 
B 2 98   SER 98   98   98  SER SER B . n 
B 2 99   TRP 99   99   99  TRP TRP B . n 
B 2 100  VAL 100  100  100 VAL VAL B . n 
B 2 101  MET 101  101  101 MET MET B . n 
B 2 102  THR 102  102  102 THR THR B . n 
B 2 103  CYS 103  103  103 CYS CYS B . n 
B 2 104  ALA 104  104  104 ALA ALA B . n 
B 2 105  TYR 105  105  105 TYR TYR B . n 
B 2 106  ALA 106  106  106 ALA ALA B . n 
B 2 107  PRO 107  107  107 PRO PRO B . n 
B 2 108  SER 108  108  108 SER SER B . n 
B 2 109  GLY 109  109  109 GLY GLY B . n 
B 2 110  ASN 110  110  110 ASN ASN B . n 
B 2 111  TYR 111  111  111 TYR TYR B . n 
B 2 112  VAL 112  112  112 VAL VAL B . n 
B 2 113  ALA 113  113  113 ALA ALA B . n 
B 2 114  CYS 114  114  114 CYS CYS B . n 
B 2 115  GLY 115  115  115 GLY GLY B . n 
B 2 116  GLY 116  116  116 GLY GLY B . n 
B 2 117  LEU 117  117  117 LEU LEU B . n 
B 2 118  ASP 118  118  118 ASP ASP B . n 
B 2 119  ASN 119  119  119 ASN ASN B . n 
B 2 120  ILE 120  120  120 ILE ILE B . n 
B 2 121  CYS 121  121  121 CYS CYS B . n 
B 2 122  SER 122  122  122 SER SER B . n 
B 2 123  ILE 123  123  123 ILE ILE B . n 
B 2 124  TYR 124  124  124 TYR TYR B . n 
B 2 125  ASN 125  125  125 ASN ASN B . n 
B 2 126  LEU 126  126  126 LEU LEU B . n 
B 2 127  LYS 127  127  127 LYS LYS B . n 
B 2 128  THR 128  128  128 THR THR B . n 
B 2 129  ARG 129  129  129 ARG ARG B . n 
B 2 130  GLU 130  130  130 GLU GLU B . n 
B 2 131  GLY 131  131  131 GLY GLY B . n 
B 2 132  ASN 132  132  132 ASN ASN B . n 
B 2 133  VAL 133  133  133 VAL VAL B . n 
B 2 134  ARG 134  134  134 ARG ARG B . n 
B 2 135  VAL 135  135  135 VAL VAL B . n 
B 2 136  SER 136  136  136 SER SER B . n 
B 2 137  ARG 137  137  137 ARG ARG B . n 
B 2 138  GLU 138  138  138 GLU GLU B . n 
B 2 139  LEU 139  139  139 LEU LEU B . n 
B 2 140  ALA 140  140  140 ALA ALA B . n 
B 2 141  GLY 141  141  141 GLY GLY B . n 
B 2 142  HIS 142  142  142 HIS HIS B . n 
B 2 143  THR 143  143  143 THR THR B . n 
B 2 144  GLY 144  144  144 GLY GLY B . n 
B 2 145  TYR 145  145  145 TYR TYR B . n 
B 2 146  LEU 146  146  146 LEU LEU B . n 
B 2 147  SER 147  147  147 SER SER B . n 
B 2 148  CYS 148  148  148 CYS CYS B . n 
B 2 149  CYS 149  149  149 CYS CYS B . n 
B 2 150  ARG 150  150  150 ARG ARG B . n 
B 2 151  PHE 151  151  151 PHE PHE B . n 
B 2 152  LEU 152  152  152 LEU LEU B . n 
B 2 153  ASP 153  153  153 ASP ASP B . n 
B 2 154  ASP 154  154  154 ASP ASP B . n 
B 2 155  ASN 155  155  155 ASN ASN B . n 
B 2 156  GLN 156  156  156 GLN GLN B . n 
B 2 157  ILE 157  157  157 ILE ILE B . n 
B 2 158  VAL 158  158  158 VAL VAL B . n 
B 2 159  THR 159  159  159 THR THR B . n 
B 2 160  SER 160  160  160 SER SER B . n 
B 2 161  SER 161  161  161 SER SER B . n 
B 2 162  GLY 162  162  162 GLY GLY B . n 
B 2 163  ASP 163  163  163 ASP ASP B . n 
B 2 164  THR 164  164  164 THR THR B . n 
B 2 165  THR 165  165  165 THR THR B . n 
B 2 166  CYS 166  166  166 CYS CYS B . n 
B 2 167  ALA 167  167  167 ALA ALA B . n 
B 2 168  LEU 168  168  168 LEU LEU B . n 
B 2 169  TRP 169  169  169 TRP TRP B . n 
B 2 170  ASP 170  170  170 ASP ASP B . n 
B 2 171  ILE 171  171  171 ILE ILE B . n 
B 2 172  GLU 172  172  172 GLU GLU B . n 
B 2 173  THR 173  173  173 THR THR B . n 
B 2 174  GLY 174  174  174 GLY GLY B . n 
B 2 175  GLN 175  175  175 GLN GLN B . n 
B 2 176  GLN 176  176  176 GLN GLN B . n 
B 2 177  THR 177  177  177 THR THR B . n 
B 2 178  THR 178  178  178 THR THR B . n 
B 2 179  THR 179  179  179 THR THR B . n 
B 2 180  PHE 180  180  180 PHE PHE B . n 
B 2 181  THR 181  181  181 THR THR B . n 
B 2 182  GLY 182  182  182 GLY GLY B . n 
B 2 183  HIS 183  183  183 HIS HIS B . n 
B 2 184  THR 184  184  184 THR THR B . n 
B 2 185  GLY 185  185  185 GLY GLY B . n 
B 2 186  ASP 186  186  186 ASP ASP B . n 
B 2 187  VAL 187  187  187 VAL VAL B . n 
B 2 188  MET 188  188  188 MET MET B . n 
B 2 189  SER 189  189  189 SER SER B . n 
B 2 190  LEU 190  190  190 LEU LEU B . n 
B 2 191  SER 191  191  191 SER SER B . n 
B 2 192  LEU 192  192  192 LEU LEU B . n 
B 2 193  ALA 193  193  193 ALA ALA B . n 
B 2 194  PRO 194  194  194 PRO PRO B . n 
B 2 195  ASP 195  195  195 ASP ASP B . n 
B 2 196  THR 196  196  196 THR THR B . n 
B 2 197  ARG 197  197  197 ARG ARG B . n 
B 2 198  LEU 198  198  198 LEU LEU B . n 
B 2 199  PHE 199  199  199 PHE PHE B . n 
B 2 200  VAL 200  200  200 VAL VAL B . n 
B 2 201  SER 201  201  201 SER SER B . n 
B 2 202  GLY 202  202  202 GLY GLY B . n 
B 2 203  ALA 203  203  203 ALA ALA B . n 
B 2 204  CYS 204  204  204 CYS CYS B . n 
B 2 205  ASP 205  205  205 ASP ASP B . n 
B 2 206  ALA 206  206  206 ALA ALA B . n 
B 2 207  SER 207  207  207 SER SER B . n 
B 2 208  ALA 208  208  208 ALA ALA B . n 
B 2 209  LYS 209  209  209 LYS LYS B . n 
B 2 210  LEU 210  210  210 LEU LEU B . n 
B 2 211  TRP 211  211  211 TRP TRP B . n 
B 2 212  ASP 212  212  212 ASP ASP B . n 
B 2 213  VAL 213  213  213 VAL VAL B . n 
B 2 214  ARG 214  214  214 ARG ARG B . n 
B 2 215  GLU 215  215  215 GLU GLU B . n 
B 2 216  GLY 216  216  216 GLY GLY B . n 
B 2 217  MET 217  217  217 MET MET B . n 
B 2 218  CYS 218  218  218 CYS CYS B . n 
B 2 219  ARG 219  219  219 ARG ARG B . n 
B 2 220  GLN 220  220  220 GLN GLN B . n 
B 2 221  THR 221  221  221 THR THR B . n 
B 2 222  PHE 222  222  222 PHE PHE B . n 
B 2 223  THR 223  223  223 THR THR B . n 
B 2 224  GLY 224  224  224 GLY GLY B . n 
B 2 225  HIS 225  225  225 HIS HIS B . n 
B 2 226  GLU 226  226  226 GLU GLU B . n 
B 2 227  SER 227  227  227 SER SER B . n 
B 2 228  ASP 228  228  228 ASP ASP B . n 
B 2 229  ILE 229  229  229 ILE ILE B . n 
B 2 230  ASN 230  230  230 ASN ASN B . n 
B 2 231  ALA 231  231  231 ALA ALA B . n 
B 2 232  ILE 232  232  232 ILE ILE B . n 
B 2 233  CYS 233  233  233 CYS CYS B . n 
B 2 234  PHE 234  234  234 PHE PHE B . n 
B 2 235  PHE 235  235  235 PHE PHE B . n 
B 2 236  PRO 236  236  236 PRO PRO B . n 
B 2 237  ASN 237  237  237 ASN ASN B . n 
B 2 238  GLY 238  238  238 GLY GLY B . n 
B 2 239  ASN 239  239  239 ASN ASN B . n 
B 2 240  ALA 240  240  240 ALA ALA B . n 
B 2 241  PHE 241  241  241 PHE PHE B . n 
B 2 242  ALA 242  242  242 ALA ALA B . n 
B 2 243  THR 243  243  243 THR THR B . n 
B 2 244  GLY 244  244  244 GLY GLY B . n 
B 2 245  SER 245  245  245 SER SER B . n 
B 2 246  ASP 246  246  246 ASP ASP B . n 
B 2 247  ASP 247  247  247 ASP ASP B . n 
B 2 248  ALA 248  248  248 ALA ALA B . n 
B 2 249  THR 249  249  249 THR THR B . n 
B 2 250  CYS 250  250  250 CYS CYS B . n 
B 2 251  ARG 251  251  251 ARG ARG B . n 
B 2 252  LEU 252  252  252 LEU LEU B . n 
B 2 253  PHE 253  253  253 PHE PHE B . n 
B 2 254  ASP 254  254  254 ASP ASP B . n 
B 2 255  LEU 255  255  255 LEU LEU B . n 
B 2 256  ARG 256  256  256 ARG ARG B . n 
B 2 257  ALA 257  257  257 ALA ALA B . n 
B 2 258  ASP 258  258  258 ASP ASP B . n 
B 2 259  GLN 259  259  259 GLN GLN B . n 
B 2 260  GLU 260  260  260 GLU GLU B . n 
B 2 261  LEU 261  261  261 LEU LEU B . n 
B 2 262  MET 262  262  262 MET MET B . n 
B 2 263  THR 263  263  263 THR THR B . n 
B 2 264  TYR 264  264  264 TYR TYR B . n 
B 2 265  SER 265  265  265 SER SER B . n 
B 2 266  HIS 266  266  266 HIS HIS B . n 
B 2 267  ASP 267  267  267 ASP ASP B . n 
B 2 268  ASN 268  268  268 ASN ASN B . n 
B 2 269  ILE 269  269  269 ILE ILE B . n 
B 2 270  ILE 270  270  270 ILE ILE B . n 
B 2 271  CYS 271  271  271 CYS CYS B . n 
B 2 272  GLY 272  272  272 GLY GLY B . n 
B 2 273  ILE 273  273  273 ILE ILE B . n 
B 2 274  THR 274  274  274 THR THR B . n 
B 2 275  SER 275  275  275 SER SER B . n 
B 2 276  VAL 276  276  276 VAL VAL B . n 
B 2 277  SER 277  277  277 SER SER B . n 
B 2 278  PHE 278  278  278 PHE PHE B . n 
B 2 279  SER 279  279  279 SER SER B . n 
B 2 280  LYS 280  280  280 LYS LYS B . n 
B 2 281  SER 281  281  281 SER SER B . n 
B 2 282  GLY 282  282  282 GLY GLY B . n 
B 2 283  ARG 283  283  283 ARG ARG B . n 
B 2 284  LEU 284  284  284 LEU LEU B . n 
B 2 285  LEU 285  285  285 LEU LEU B . n 
B 2 286  LEU 286  286  286 LEU LEU B . n 
B 2 287  ALA 287  287  287 ALA ALA B . n 
B 2 288  GLY 288  288  288 GLY GLY B . n 
B 2 289  TYR 289  289  289 TYR TYR B . n 
B 2 290  ASP 290  290  290 ASP ASP B . n 
B 2 291  ASP 291  291  291 ASP ASP B . n 
B 2 292  PHE 292  292  292 PHE PHE B . n 
B 2 293  ASN 293  293  293 ASN ASN B . n 
B 2 294  CYS 294  294  294 CYS CYS B . n 
B 2 295  ASN 295  295  295 ASN ASN B . n 
B 2 296  VAL 296  296  296 VAL VAL B . n 
B 2 297  TRP 297  297  297 TRP TRP B . n 
B 2 298  ASP 298  298  298 ASP ASP B . n 
B 2 299  ALA 299  299  299 ALA ALA B . n 
B 2 300  LEU 300  300  300 LEU LEU B . n 
B 2 301  LYS 301  301  301 LYS LYS B . n 
B 2 302  ALA 302  302  302 ALA ALA B . n 
B 2 303  ASP 303  303  303 ASP ASP B . n 
B 2 304  ARG 304  304  304 ARG ARG B . n 
B 2 305  ALA 305  305  305 ALA ALA B . n 
B 2 306  GLY 306  306  306 GLY GLY B . n 
B 2 307  VAL 307  307  307 VAL VAL B . n 
B 2 308  LEU 308  308  308 LEU LEU B . n 
B 2 309  ALA 309  309  309 ALA ALA B . n 
B 2 310  GLY 310  310  310 GLY GLY B . n 
B 2 311  HIS 311  311  311 HIS HIS B . n 
B 2 312  ASP 312  312  312 ASP ASP B . n 
B 2 313  ASN 313  313  313 ASN ASN B . n 
B 2 314  ARG 314  314  314 ARG ARG B . n 
B 2 315  VAL 315  315  315 VAL VAL B . n 
B 2 316  SER 316  316  316 SER SER B . n 
B 2 317  CYS 317  317  317 CYS CYS B . n 
B 2 318  LEU 318  318  318 LEU LEU B . n 
B 2 319  GLY 319  319  319 GLY GLY B . n 
B 2 320  VAL 320  320  320 VAL VAL B . n 
B 2 321  THR 321  321  321 THR THR B . n 
B 2 322  ASP 322  322  322 ASP ASP B . n 
B 2 323  ASP 323  323  323 ASP ASP B . n 
B 2 324  GLY 324  324  324 GLY GLY B . n 
B 2 325  MET 325  325  325 MET MET B . n 
B 2 326  ALA 326  326  326 ALA ALA B . n 
B 2 327  VAL 327  327  327 VAL VAL B . n 
B 2 328  ALA 328  328  328 ALA ALA B . n 
B 2 329  THR 329  329  329 THR THR B . n 
B 2 330  GLY 330  330  330 GLY GLY B . n 
B 2 331  SER 331  331  331 SER SER B . n 
B 2 332  TRP 332  332  332 TRP TRP B . n 
B 2 333  ASP 333  333  333 ASP ASP B . n 
B 2 334  SER 334  334  334 SER SER B . n 
B 2 335  PHE 335  335  335 PHE PHE B . n 
B 2 336  LEU 336  336  336 LEU LEU B . n 
B 2 337  LYS 337  337  337 LYS LYS B . n 
B 2 338  ILE 338  338  338 ILE ILE B . n 
B 2 339  TRP 339  339  339 TRP TRP B . n 
B 2 340  ASN 340  340  340 ASN ASN B . n 
B 2 341  GLY 341  341  341 GLY GLY B . n 
B 2 342  SER 342  342  342 SER SER B . n 
B 2 343  SER 343  343  343 SER SER B . n 
B 2 344  GLY 344  344  ?   ?   ?   B . n 
B 2 345  GLY 345  345  ?   ?   ?   B . n 
B 2 346  GLY 346  346  ?   ?   ?   B . n 
B 2 347  GLY 347  347  ?   ?   ?   B . n 
B 2 348  SER 348  348  ?   ?   ?   B . n 
B 2 349  GLY 349  349  ?   ?   ?   B . n 
B 2 350  GLY 350  350  ?   ?   ?   B . n 
B 2 351  GLY 351  351  ?   ?   ?   B . n 
B 2 352  GLY 352  352  ?   ?   ?   B . n 
B 2 353  SER 353  353  ?   ?   ?   B . n 
B 2 354  SER 354  354  ?   ?   ?   B . n 
B 2 355  GLY 355  355  ?   ?   ?   B . n 
B 2 356  VAL 356  356  ?   ?   ?   B . n 
B 2 357  SER 357  357  ?   ?   ?   B . n 
B 2 358  GLY 358  358  ?   ?   ?   B . n 
B 2 359  TRP 359  359  ?   ?   ?   B . n 
B 2 360  ARG 360  360  ?   ?   ?   B . n 
B 2 361  LEU 361  361  ?   ?   ?   B . n 
B 2 362  PHE 362  362  ?   ?   ?   B . n 
B 2 363  LYS 363  363  ?   ?   ?   B . n 
B 2 364  LYS 364  364  ?   ?   ?   B . n 
B 2 365  ILE 365  365  ?   ?   ?   B . n 
B 2 366  SER 366  366  ?   ?   ?   B . n 
C 3 1    MET 1    1    ?   ?   ?   G . n 
C 3 2    ALA 2    2    ?   ?   ?   G . n 
C 3 3    SER 3    3    ?   ?   ?   G . n 
C 3 4    ASN 4    4    ?   ?   ?   G . n 
C 3 5    ASN 5    5    ?   ?   ?   G . n 
C 3 6    THR 6    6    6   THR THR G . n 
C 3 7    ALA 7    7    7   ALA ALA G . n 
C 3 8    SER 8    8    8   SER SER G . n 
C 3 9    ILE 9    9    9   ILE ILE G . n 
C 3 10   ALA 10   10   10  ALA ALA G . n 
C 3 11   GLN 11   11   11  GLN GLN G . n 
C 3 12   ALA 12   12   12  ALA ALA G . n 
C 3 13   ARG 13   13   13  ARG ARG G . n 
C 3 14   LYS 14   14   14  LYS LYS G . n 
C 3 15   LEU 15   15   15  LEU LEU G . n 
C 3 16   VAL 16   16   16  VAL VAL G . n 
C 3 17   GLU 17   17   17  GLU GLU G . n 
C 3 18   GLN 18   18   18  GLN GLN G . n 
C 3 19   LEU 19   19   19  LEU LEU G . n 
C 3 20   LYS 20   20   20  LYS LYS G . n 
C 3 21   MET 21   21   21  MET MET G . n 
C 3 22   GLU 22   22   22  GLU GLU G . n 
C 3 23   ALA 23   23   23  ALA ALA G . n 
C 3 24   ASN 24   24   24  ASN ASN G . n 
C 3 25   ILE 25   25   25  ILE ILE G . n 
C 3 26   ASP 26   26   26  ASP ASP G . n 
C 3 27   ARG 27   27   27  ARG ARG G . n 
C 3 28   ILE 28   28   28  ILE ILE G . n 
C 3 29   LYS 29   29   29  LYS LYS G . n 
C 3 30   VAL 30   30   30  VAL VAL G . n 
C 3 31   SER 31   31   31  SER SER G . n 
C 3 32   LYS 32   32   32  LYS LYS G . n 
C 3 33   ALA 33   33   33  ALA ALA G . n 
C 3 34   ALA 34   34   34  ALA ALA G . n 
C 3 35   ALA 35   35   35  ALA ALA G . n 
C 3 36   ASP 36   36   36  ASP ASP G . n 
C 3 37   LEU 37   37   37  LEU LEU G . n 
C 3 38   MET 38   38   38  MET MET G . n 
C 3 39   ALA 39   39   39  ALA ALA G . n 
C 3 40   TYR 40   40   40  TYR TYR G . n 
C 3 41   CYS 41   41   41  CYS CYS G . n 
C 3 42   GLU 42   42   42  GLU GLU G . n 
C 3 43   ALA 43   43   43  ALA ALA G . n 
C 3 44   HIS 44   44   44  HIS HIS G . n 
C 3 45   ALA 45   45   45  ALA ALA G . n 
C 3 46   LYS 46   46   46  LYS LYS G . n 
C 3 47   GLU 47   47   47  GLU GLU G . n 
C 3 48   ASP 48   48   48  ASP ASP G . n 
C 3 49   PRO 49   49   49  PRO PRO G . n 
C 3 50   LEU 50   50   50  LEU LEU G . n 
C 3 51   LEU 51   51   51  LEU LEU G . n 
C 3 52   THR 52   52   52  THR THR G . n 
C 3 53   PRO 53   53   53  PRO PRO G . n 
C 3 54   VAL 54   54   54  VAL VAL G . n 
C 3 55   PRO 55   55   55  PRO PRO G . n 
C 3 56   ALA 56   56   56  ALA ALA G . n 
C 3 57   SER 57   57   57  SER SER G . n 
C 3 58   GLU 58   58   58  GLU GLU G . n 
C 3 59   ASN 59   59   59  ASN ASN G . n 
C 3 60   PRO 60   60   60  PRO PRO G . n 
C 3 61   PHE 61   61   61  PHE PHE G . n 
C 3 62   ARG 62   62   62  ARG ARG G . n 
C 3 63   GLU 63   63   ?   ?   ?   G . n 
C 3 64   LYS 64   64   ?   ?   ?   G . n 
C 3 65   LYS 65   65   ?   ?   ?   G . n 
C 3 66   PHE 66   66   ?   ?   ?   G . n 
C 3 67   PHE 67   67   ?   ?   ?   G . n 
C 3 68   CYS 68   68   ?   ?   ?   G . n 
C 3 69   ALA 69   69   ?   ?   ?   G . n 
C 3 70   ILE 70   70   ?   ?   ?   G . n 
C 3 71   LEU 71   71   ?   ?   ?   G . n 
D 4 1    ASP 1    1    ?   ?   ?   S . n 
D 4 2    VAL 2    2    2   VAL VAL S . n 
D 4 3    GLN 3    3    3   GLN GLN S . n 
D 4 4    LEU 4    4    4   LEU LEU S . n 
D 4 5    VAL 5    5    5   VAL VAL S . n 
D 4 6    GLU 6    6    6   GLU GLU S . n 
D 4 7    SER 7    7    7   SER SER S . n 
D 4 8    GLY 8    8    8   GLY GLY S . n 
D 4 9    GLY 9    9    9   GLY GLY S . n 
D 4 10   GLY 10   10   10  GLY GLY S . n 
D 4 11   LEU 11   11   11  LEU LEU S . n 
D 4 12   VAL 12   12   12  VAL VAL S . n 
D 4 13   GLN 13   13   13  GLN GLN S . n 
D 4 14   PRO 14   14   14  PRO PRO S . n 
D 4 15   GLY 15   15   15  GLY GLY S . n 
D 4 16   GLY 16   16   16  GLY GLY S . n 
D 4 17   SER 17   17   17  SER SER S . n 
D 4 18   ARG 18   18   18  ARG ARG S . n 
D 4 19   LYS 19   19   19  LYS LYS S . n 
D 4 20   LEU 20   20   20  LEU LEU S . n 
D 4 21   SER 21   21   21  SER SER S . n 
D 4 22   CYS 22   22   22  CYS CYS S . n 
D 4 23   SER 23   23   23  SER SER S . n 
D 4 24   ALA 24   24   24  ALA ALA S . n 
D 4 25   SER 25   25   25  SER SER S . n 
D 4 26   GLY 26   26   26  GLY GLY S . n 
D 4 27   PHE 27   27   27  PHE PHE S . n 
D 4 28   ALA 28   28   28  ALA ALA S . n 
D 4 29   PHE 29   29   29  PHE PHE S . n 
D 4 30   SER 30   30   30  SER SER S . n 
D 4 31   SER 31   31   31  SER SER S . n 
D 4 32   PHE 32   32   32  PHE PHE S . n 
D 4 33   GLY 33   33   33  GLY GLY S . n 
D 4 34   MET 34   34   34  MET MET S . n 
D 4 35   HIS 35   35   35  HIS HIS S . n 
D 4 36   TRP 36   36   36  TRP TRP S . n 
D 4 37   VAL 37   37   37  VAL VAL S . n 
D 4 38   ARG 38   38   38  ARG ARG S . n 
D 4 39   GLN 39   39   39  GLN GLN S . n 
D 4 40   ALA 40   40   40  ALA ALA S . n 
D 4 41   PRO 41   41   41  PRO PRO S . n 
D 4 42   GLU 42   42   42  GLU GLU S . n 
D 4 43   LYS 43   43   43  LYS LYS S . n 
D 4 44   GLY 44   44   44  GLY GLY S . n 
D 4 45   LEU 45   45   45  LEU LEU S . n 
D 4 46   GLU 46   46   46  GLU GLU S . n 
D 4 47   TRP 47   47   47  TRP TRP S . n 
D 4 48   VAL 48   48   48  VAL VAL S . n 
D 4 49   ALA 49   49   49  ALA ALA S . n 
D 4 50   TYR 50   50   50  TYR TYR S . n 
D 4 51   ILE 51   51   51  ILE ILE S . n 
D 4 52   SER 52   52   52  SER SER S . n 
D 4 53   SER 53   53   53  SER SER S . n 
D 4 54   GLY 54   54   54  GLY GLY S . n 
D 4 55   SER 55   55   55  SER SER S . n 
D 4 56   GLY 56   56   56  GLY GLY S . n 
D 4 57   THR 57   57   57  THR THR S . n 
D 4 58   ILE 58   58   58  ILE ILE S . n 
D 4 59   TYR 59   59   59  TYR TYR S . n 
D 4 60   TYR 60   60   60  TYR TYR S . n 
D 4 61   ALA 61   61   61  ALA ALA S . n 
D 4 62   ASP 62   62   62  ASP ASP S . n 
D 4 63   THR 63   63   63  THR THR S . n 
D 4 64   VAL 64   64   64  VAL VAL S . n 
D 4 65   LYS 65   65   65  LYS LYS S . n 
D 4 66   GLY 66   66   66  GLY GLY S . n 
D 4 67   ARG 67   67   67  ARG ARG S . n 
D 4 68   PHE 68   68   68  PHE PHE S . n 
D 4 69   THR 69   69   69  THR THR S . n 
D 4 70   ILE 70   70   70  ILE ILE S . n 
D 4 71   SER 71   71   71  SER SER S . n 
D 4 72   ARG 72   72   72  ARG ARG S . n 
D 4 73   ASP 73   73   73  ASP ASP S . n 
D 4 74   ASP 74   74   74  ASP ASP S . n 
D 4 75   PRO 75   75   75  PRO PRO S . n 
D 4 76   LYS 76   76   76  LYS LYS S . n 
D 4 77   ASN 77   77   77  ASN ASN S . n 
D 4 78   THR 78   78   78  THR THR S . n 
D 4 79   LEU 79   79   79  LEU LEU S . n 
D 4 80   PHE 80   80   80  PHE PHE S . n 
D 4 81   LEU 81   81   81  LEU LEU S . n 
D 4 82   GLN 82   82   82  GLN GLN S . n 
D 4 83   MET 83   83   83  MET MET S . n 
D 4 84   THR 84   84   84  THR THR S . n 
D 4 85   SER 85   85   85  SER SER S . n 
D 4 86   LEU 86   86   86  LEU LEU S . n 
D 4 87   ARG 87   87   87  ARG ARG S . n 
D 4 88   SER 88   88   88  SER SER S . n 
D 4 89   GLU 89   89   89  GLU GLU S . n 
D 4 90   ASP 90   90   90  ASP ASP S . n 
D 4 91   THR 91   91   91  THR THR S . n 
D 4 92   ALA 92   92   92  ALA ALA S . n 
D 4 93   MET 93   93   93  MET MET S . n 
D 4 94   TYR 94   94   94  TYR TYR S . n 
D 4 95   TYR 95   95   95  TYR TYR S . n 
D 4 96   CYS 96   96   96  CYS CYS S . n 
D 4 97   VAL 97   97   97  VAL VAL S . n 
D 4 98   ARG 98   98   98  ARG ARG S . n 
D 4 99   SER 99   99   99  SER SER S . n 
D 4 100  ILE 100  100  100 ILE ILE S . n 
D 4 101  TYR 101  101  101 TYR TYR S . n 
D 4 102  TYR 102  102  102 TYR TYR S . n 
D 4 103  TYR 103  103  103 TYR TYR S . n 
D 4 104  GLY 104  104  104 GLY GLY S . n 
D 4 105  SER 105  105  105 SER SER S . n 
D 4 106  SER 106  106  106 SER SER S . n 
D 4 107  PRO 107  107  107 PRO PRO S . n 
D 4 108  PHE 108  108  108 PHE PHE S . n 
D 4 109  ASP 109  109  109 ASP ASP S . n 
D 4 110  PHE 110  110  110 PHE PHE S . n 
D 4 111  TRP 111  111  111 TRP TRP S . n 
D 4 112  GLY 112  112  112 GLY GLY S . n 
D 4 113  GLN 113  113  113 GLN GLN S . n 
D 4 114  GLY 114  114  114 GLY GLY S . n 
D 4 115  THR 115  115  115 THR THR S . n 
D 4 116  THR 116  116  116 THR THR S . n 
D 4 117  LEU 117  117  117 LEU LEU S . n 
D 4 118  THR 118  118  118 THR THR S . n 
D 4 119  VAL 119  119  119 VAL VAL S . n 
D 4 120  SER 120  120  120 SER SER S . n 
D 4 121  SER 121  121  121 SER SER S . n 
D 4 122  GLY 122  121  ?   ?   ?   S A n 
D 4 123  GLY 123  121  ?   ?   ?   S B n 
D 4 124  GLY 124  121  ?   ?   ?   S C n 
D 4 125  GLY 125  121  ?   ?   ?   S D n 
D 4 126  SER 126  121  ?   ?   ?   S E n 
D 4 127  GLY 127  121  ?   ?   ?   S F n 
D 4 128  GLY 128  121  ?   ?   ?   S G n 
D 4 129  GLY 129  121  ?   ?   ?   S H n 
D 4 130  GLY 130  121  ?   ?   ?   S I n 
D 4 131  SER 131  121  ?   ?   ?   S J n 
D 4 132  GLY 132  121  ?   ?   ?   S K n 
D 4 133  GLY 133  121  ?   ?   ?   S L n 
D 4 134  GLY 134  121  ?   ?   ?   S M n 
D 4 135  GLY 135  121  ?   ?   ?   S N n 
D 4 136  SER 136  124  124 SER SER S . n 
D 4 137  ASP 137  125  125 ASP ASP S . n 
D 4 138  ILE 138  126  126 ILE ILE S . n 
D 4 139  VAL 139  127  127 VAL VAL S . n 
D 4 140  MET 140  128  128 MET MET S . n 
D 4 141  THR 141  129  129 THR THR S . n 
D 4 142  GLN 142  130  130 GLN GLN S . n 
D 4 143  ALA 143  131  131 ALA ALA S . n 
D 4 144  THR 144  132  132 THR THR S . n 
D 4 145  SER 145  133  133 SER SER S . n 
D 4 146  SER 146  134  134 SER SER S . n 
D 4 147  VAL 147  135  135 VAL VAL S . n 
D 4 148  PRO 148  136  136 PRO PRO S . n 
D 4 149  VAL 149  137  137 VAL VAL S . n 
D 4 150  THR 150  138  138 THR THR S . n 
D 4 151  PRO 151  139  139 PRO PRO S . n 
D 4 152  GLY 152  140  140 GLY GLY S . n 
D 4 153  GLU 153  141  141 GLU GLU S . n 
D 4 154  SER 154  142  142 SER SER S . n 
D 4 155  VAL 155  143  143 VAL VAL S . n 
D 4 156  SER 156  144  144 SER SER S . n 
D 4 157  ILE 157  145  145 ILE ILE S . n 
D 4 158  SER 158  146  146 SER SER S . n 
D 4 159  CYS 159  147  147 CYS CYS S . n 
D 4 160  ARG 160  148  148 ARG ARG S . n 
D 4 161  SER 161  149  149 SER SER S . n 
D 4 162  SER 162  150  150 SER SER S . n 
D 4 163  LYS 163  151  151 LYS LYS S . n 
D 4 164  SER 164  152  152 SER SER S . n 
D 4 165  LEU 165  153  153 LEU LEU S . n 
D 4 166  LEU 166  154  154 LEU LEU S . n 
D 4 167  HIS 167  155  155 HIS HIS S . n 
D 4 168  SER 168  156  156 SER SER S . n 
D 4 169  ASN 169  157  157 ASN ASN S . n 
D 4 170  GLY 170  158  158 GLY GLY S . n 
D 4 171  ASN 171  159  159 ASN ASN S . n 
D 4 172  THR 172  160  160 THR THR S . n 
D 4 173  TYR 173  161  161 TYR TYR S . n 
D 4 174  LEU 174  162  162 LEU LEU S . n 
D 4 175  TYR 175  163  163 TYR TYR S . n 
D 4 176  TRP 176  164  164 TRP TRP S . n 
D 4 177  PHE 177  165  165 PHE PHE S . n 
D 4 178  LEU 178  166  166 LEU LEU S . n 
D 4 179  GLN 179  167  167 GLN GLN S . n 
D 4 180  ARG 180  168  168 ARG ARG S . n 
D 4 181  PRO 181  169  169 PRO PRO S . n 
D 4 182  GLY 182  170  170 GLY GLY S . n 
D 4 183  GLN 183  171  171 GLN GLN S . n 
D 4 184  SER 184  172  172 SER SER S . n 
D 4 185  PRO 185  173  173 PRO PRO S . n 
D 4 186  GLN 186  174  174 GLN GLN S . n 
D 4 187  LEU 187  175  175 LEU LEU S . n 
D 4 188  LEU 188  176  176 LEU LEU S . n 
D 4 189  ILE 189  177  177 ILE ILE S . n 
D 4 190  TYR 190  178  178 TYR TYR S . n 
D 4 191  ARG 191  179  179 ARG ARG S . n 
D 4 192  MET 192  180  180 MET MET S . n 
D 4 193  SER 193  181  181 SER SER S . n 
D 4 194  ASN 194  182  182 ASN ASN S . n 
D 4 195  LEU 195  183  183 LEU LEU S . n 
D 4 196  ALA 196  184  184 ALA ALA S . n 
D 4 197  SER 197  185  185 SER SER S . n 
D 4 198  GLY 198  186  186 GLY GLY S . n 
D 4 199  VAL 199  187  187 VAL VAL S . n 
D 4 200  PRO 200  188  188 PRO PRO S . n 
D 4 201  ASP 201  189  189 ASP ASP S . n 
D 4 202  ARG 202  190  190 ARG ARG S . n 
D 4 203  PHE 203  191  191 PHE PHE S . n 
D 4 204  SER 204  192  192 SER SER S . n 
D 4 205  GLY 205  193  193 GLY GLY S . n 
D 4 206  SER 206  194  194 SER SER S . n 
D 4 207  GLY 207  195  195 GLY GLY S . n 
D 4 208  SER 208  196  196 SER SER S . n 
D 4 209  GLY 209  197  197 GLY GLY S . n 
D 4 210  THR 210  198  198 THR THR S . n 
D 4 211  ALA 211  199  199 ALA ALA S . n 
D 4 212  PHE 212  200  200 PHE PHE S . n 
D 4 213  THR 213  201  201 THR THR S . n 
D 4 214  LEU 214  202  202 LEU LEU S . n 
D 4 215  THR 215  203  203 THR THR S . n 
D 4 216  ILE 216  204  204 ILE ILE S . n 
D 4 217  SER 217  205  205 SER SER S . n 
D 4 218  ARG 218  206  206 ARG ARG S . n 
D 4 219  LEU 219  207  207 LEU LEU S . n 
D 4 220  GLU 220  208  208 GLU GLU S . n 
D 4 221  ALA 221  209  209 ALA ALA S . n 
D 4 222  GLU 222  210  210 GLU GLU S . n 
D 4 223  ASP 223  211  211 ASP ASP S . n 
D 4 224  VAL 224  212  212 VAL VAL S . n 
D 4 225  GLY 225  213  213 GLY GLY S . n 
D 4 226  VAL 226  214  214 VAL VAL S . n 
D 4 227  TYR 227  215  215 TYR TYR S . n 
D 4 228  TYR 228  216  216 TYR TYR S . n 
D 4 229  CYS 229  217  217 CYS CYS S . n 
D 4 230  MET 230  218  218 MET MET S . n 
D 4 231  GLN 231  219  219 GLN GLN S . n 
D 4 232  HIS 232  220  220 HIS HIS S . n 
D 4 233  LEU 233  221  221 LEU LEU S . n 
D 4 234  GLU 234  222  222 GLU GLU S . n 
D 4 235  TYR 235  223  223 TYR TYR S . n 
D 4 236  PRO 236  224  224 PRO PRO S . n 
D 4 237  LEU 237  225  225 LEU LEU S . n 
D 4 238  THR 238  226  226 THR THR S . n 
D 4 239  PHE 239  227  227 PHE PHE S . n 
D 4 240  GLY 240  228  228 GLY GLY S . n 
D 4 241  ALA 241  229  229 ALA ALA S . n 
D 4 242  GLY 242  230  230 GLY GLY S . n 
D 4 243  THR 243  231  231 THR THR S . n 
D 4 244  LYS 244  232  232 LYS LYS S . n 
D 4 245  LEU 245  233  233 LEU LEU S . n 
D 4 246  GLU 246  234  234 GLU GLU S . n 
D 4 247  LEU 247  235  235 LEU LEU S . n 
D 4 248  LYS 248  236  ?   ?   ?   S . n 
D 4 249  ALA 249  237  ?   ?   ?   S . n 
D 4 250  ALA 250  238  ?   ?   ?   S . n 
D 4 251  ALA 251  239  ?   ?   ?   S . n 
D 4 252  GLU 252  240  ?   ?   ?   S . n 
D 4 253  ASN 253  241  ?   ?   ?   S . n 
D 4 254  LEU 254  242  ?   ?   ?   S . n 
D 4 255  TYR 255  243  ?   ?   ?   S . n 
D 4 256  PHE 256  244  ?   ?   ?   S . n 
D 4 257  GLN 257  245  ?   ?   ?   S . n 
D 4 258  SER 258  246  ?   ?   ?   S . n 
D 4 259  HIS 259  247  ?   ?   ?   S . n 
D 4 260  HIS 260  248  ?   ?   ?   S . n 
D 4 261  HIS 261  249  ?   ?   ?   S . n 
D 4 262  HIS 262  250  ?   ?   ?   S . n 
D 4 263  HIS 263  251  ?   ?   ?   S . n 
D 4 264  HIS 264  252  ?   ?   ?   S . n 
D 4 265  HIS 265  253  ?   ?   ?   S . n 
D 4 266  HIS 266  254  ?   ?   ?   S . n 
E 5 1    MET 1    -537 ?   ?   ?   R . n 
E 5 2    LYS 2    -536 ?   ?   ?   R . n 
E 5 3    THR 3    -535 ?   ?   ?   R . n 
E 5 4    ILE 4    -534 ?   ?   ?   R . n 
E 5 5    ILE 5    -533 ?   ?   ?   R . n 
E 5 6    ALA 6    -532 ?   ?   ?   R . n 
E 5 7    LEU 7    -531 ?   ?   ?   R . n 
E 5 8    SER 8    -530 ?   ?   ?   R . n 
E 5 9    TYR 9    -529 ?   ?   ?   R . n 
E 5 10   ILE 10   -528 ?   ?   ?   R . n 
E 5 11   PHE 11   -527 ?   ?   ?   R . n 
E 5 12   CYS 12   -526 ?   ?   ?   R . n 
E 5 13   LEU 13   -525 ?   ?   ?   R . n 
E 5 14   VAL 14   -524 ?   ?   ?   R . n 
E 5 15   PHE 15   -523 ?   ?   ?   R . n 
E 5 16   ALA 16   -522 ?   ?   ?   R . n 
E 5 17   ASP 17   -521 ?   ?   ?   R . n 
E 5 18   TYR 18   -520 ?   ?   ?   R . n 
E 5 19   LYS 19   -519 ?   ?   ?   R . n 
E 5 20   ASP 20   -518 ?   ?   ?   R . n 
E 5 21   ASP 21   -517 ?   ?   ?   R . n 
E 5 22   ASP 22   -516 ?   ?   ?   R . n 
E 5 23   ASP 23   -515 ?   ?   ?   R . n 
E 5 24   ALA 24   -514 ?   ?   ?   R . n 
E 5 25   HIS 25   -513 ?   ?   ?   R . n 
E 5 26   HIS 26   -512 ?   ?   ?   R . n 
E 5 27   HIS 27   -511 ?   ?   ?   R . n 
E 5 28   HIS 28   -510 ?   ?   ?   R . n 
E 5 29   HIS 29   -509 ?   ?   ?   R . n 
E 5 30   HIS 30   -508 ?   ?   ?   R . n 
E 5 31   HIS 31   -507 ?   ?   ?   R . n 
E 5 32   HIS 32   -506 ?   ?   ?   R . n 
E 5 33   HIS 33   -505 ?   ?   ?   R . n 
E 5 34   HIS 34   -504 ?   ?   ?   R . n 
E 5 35   GLU 35   -503 ?   ?   ?   R . n 
E 5 36   ASN 36   -502 ?   ?   ?   R . n 
E 5 37   LEU 37   -501 ?   ?   ?   R . n 
E 5 38   TYR 38   -500 ?   ?   ?   R . n 
E 5 39   PHE 39   -499 ?   ?   ?   R . n 
E 5 40   GLN 40   -498 ?   ?   ?   R . n 
E 5 41   SER 41   -497 ?   ?   ?   R . n 
E 5 42   ALA 42   -496 ?   ?   ?   R . n 
E 5 43   HIS 43   -495 ?   ?   ?   R . n 
E 5 44   HIS 44   -494 ?   ?   ?   R . n 
E 5 45   HIS 45   -493 ?   ?   ?   R . n 
E 5 46   HIS 46   -492 ?   ?   ?   R . n 
E 5 47   HIS 47   -491 ?   ?   ?   R . n 
E 5 48   HIS 48   -490 ?   ?   ?   R . n 
E 5 49   SER 49   -489 ?   ?   ?   R . n 
E 5 50   SER 50   -488 ?   ?   ?   R . n 
E 5 51   GLY 51   -487 ?   ?   ?   R . n 
E 5 52   LEU 52   -486 ?   ?   ?   R . n 
E 5 53   GLU 53   -485 ?   ?   ?   R . n 
E 5 54   VAL 54   -484 ?   ?   ?   R . n 
E 5 55   LEU 55   -483 ?   ?   ?   R . n 
E 5 56   PHE 56   -482 ?   ?   ?   R . n 
E 5 57   GLN 57   -481 ?   ?   ?   R . n 
E 5 58   GLY 58   -480 ?   ?   ?   R . n 
E 5 59   PRO 59   -479 ?   ?   ?   R . n 
E 5 60   PRO 60   -478 ?   ?   ?   R . n 
E 5 61   GLU 61   -477 ?   ?   ?   R . n 
E 5 62   GLY 62   -476 ?   ?   ?   R . n 
E 5 63   ALA 63   -475 ?   ?   ?   R . n 
E 5 64   ALA 64   -474 ?   ?   ?   R . n 
E 5 65   LEU 65   -473 ?   ?   ?   R . n 
E 5 66   THR 66   -472 ?   ?   ?   R . n 
E 5 67   GLU 67   -471 ?   ?   ?   R . n 
E 5 68   LYS 68   -470 ?   ?   ?   R . n 
E 5 69   THR 69   -469 ?   ?   ?   R . n 
E 5 70   ASP 70   -468 ?   ?   ?   R . n 
E 5 71   ILE 71   -467 ?   ?   ?   R . n 
E 5 72   PHE 72   -466 ?   ?   ?   R . n 
E 5 73   GLU 73   -465 ?   ?   ?   R . n 
E 5 74   SER 74   -464 ?   ?   ?   R . n 
E 5 75   GLY 75   -463 ?   ?   ?   R . n 
E 5 76   ARG 76   -462 ?   ?   ?   R . n 
E 5 77   ASN 77   -461 ?   ?   ?   R . n 
E 5 78   GLY 78   -460 ?   ?   ?   R . n 
E 5 79   ASN 79   -459 ?   ?   ?   R . n 
E 5 80   PRO 80   -458 ?   ?   ?   R . n 
E 5 81   ASN 81   -457 ?   ?   ?   R . n 
E 5 82   LYS 82   -456 ?   ?   ?   R . n 
E 5 83   ASP 83   -455 ?   ?   ?   R . n 
E 5 84   GLY 84   -454 ?   ?   ?   R . n 
E 5 85   ILE 85   -453 ?   ?   ?   R . n 
E 5 86   LYS 86   -452 ?   ?   ?   R . n 
E 5 87   SER 87   -451 ?   ?   ?   R . n 
E 5 88   TYR 88   -450 ?   ?   ?   R . n 
E 5 89   ARG 89   -449 ?   ?   ?   R . n 
E 5 90   ILE 90   -448 ?   ?   ?   R . n 
E 5 91   PRO 91   -447 ?   ?   ?   R . n 
E 5 92   ALA 92   -446 ?   ?   ?   R . n 
E 5 93   LEU 93   -445 ?   ?   ?   R . n 
E 5 94   LEU 94   -444 ?   ?   ?   R . n 
E 5 95   LYS 95   -443 ?   ?   ?   R . n 
E 5 96   THR 96   -442 ?   ?   ?   R . n 
E 5 97   ASP 97   -441 ?   ?   ?   R . n 
E 5 98   LYS 98   -440 ?   ?   ?   R . n 
E 5 99   GLY 99   -439 ?   ?   ?   R . n 
E 5 100  THR 100  -438 ?   ?   ?   R . n 
E 5 101  LEU 101  -437 ?   ?   ?   R . n 
E 5 102  ILE 102  -436 ?   ?   ?   R . n 
E 5 103  ALA 103  -435 ?   ?   ?   R . n 
E 5 104  GLY 104  -434 ?   ?   ?   R . n 
E 5 105  ALA 105  -433 ?   ?   ?   R . n 
E 5 106  ASP 106  -432 ?   ?   ?   R . n 
E 5 107  GLU 107  -431 ?   ?   ?   R . n 
E 5 108  ARG 108  -430 ?   ?   ?   R . n 
E 5 109  ARG 109  -429 ?   ?   ?   R . n 
E 5 110  LEU 110  -428 ?   ?   ?   R . n 
E 5 111  HIS 111  -427 ?   ?   ?   R . n 
E 5 112  SER 112  -426 ?   ?   ?   R . n 
E 5 113  SER 113  -425 ?   ?   ?   R . n 
E 5 114  ASP 114  -424 ?   ?   ?   R . n 
E 5 115  TRP 115  -423 ?   ?   ?   R . n 
E 5 116  GLY 116  -422 ?   ?   ?   R . n 
E 5 117  ASP 117  -421 ?   ?   ?   R . n 
E 5 118  ILE 118  -420 ?   ?   ?   R . n 
E 5 119  GLY 119  -419 ?   ?   ?   R . n 
E 5 120  MET 120  -418 ?   ?   ?   R . n 
E 5 121  VAL 121  -417 ?   ?   ?   R . n 
E 5 122  ILE 122  -416 ?   ?   ?   R . n 
E 5 123  ARG 123  -415 ?   ?   ?   R . n 
E 5 124  ARG 124  -414 ?   ?   ?   R . n 
E 5 125  SER 125  -413 ?   ?   ?   R . n 
E 5 126  GLU 126  -412 ?   ?   ?   R . n 
E 5 127  ASP 127  -411 ?   ?   ?   R . n 
E 5 128  ASN 128  -410 ?   ?   ?   R . n 
E 5 129  GLY 129  -409 ?   ?   ?   R . n 
E 5 130  LYS 130  -408 ?   ?   ?   R . n 
E 5 131  THR 131  -407 ?   ?   ?   R . n 
E 5 132  TRP 132  -406 ?   ?   ?   R . n 
E 5 133  GLY 133  -405 ?   ?   ?   R . n 
E 5 134  ASP 134  -404 ?   ?   ?   R . n 
E 5 135  ARG 135  -403 ?   ?   ?   R . n 
E 5 136  VAL 136  -402 ?   ?   ?   R . n 
E 5 137  THR 137  -401 ?   ?   ?   R . n 
E 5 138  ILE 138  -400 ?   ?   ?   R . n 
E 5 139  THR 139  -399 ?   ?   ?   R . n 
E 5 140  ASN 140  -398 ?   ?   ?   R . n 
E 5 141  LEU 141  -397 ?   ?   ?   R . n 
E 5 142  ARG 142  -396 ?   ?   ?   R . n 
E 5 143  ASP 143  -395 ?   ?   ?   R . n 
E 5 144  ASN 144  -394 ?   ?   ?   R . n 
E 5 145  PRO 145  -393 ?   ?   ?   R . n 
E 5 146  LYS 146  -392 ?   ?   ?   R . n 
E 5 147  ALA 147  -391 ?   ?   ?   R . n 
E 5 148  SER 148  -390 ?   ?   ?   R . n 
E 5 149  ASP 149  -389 ?   ?   ?   R . n 
E 5 150  PRO 150  -388 ?   ?   ?   R . n 
E 5 151  SER 151  -387 ?   ?   ?   R . n 
E 5 152  ILE 152  -386 ?   ?   ?   R . n 
E 5 153  GLY 153  -385 ?   ?   ?   R . n 
E 5 154  SER 154  -384 ?   ?   ?   R . n 
E 5 155  PRO 155  -383 ?   ?   ?   R . n 
E 5 156  VAL 156  -382 ?   ?   ?   R . n 
E 5 157  ASN 157  -381 ?   ?   ?   R . n 
E 5 158  ILE 158  -380 ?   ?   ?   R . n 
E 5 159  ASP 159  -379 ?   ?   ?   R . n 
E 5 160  MET 160  -378 ?   ?   ?   R . n 
E 5 161  VAL 161  -377 ?   ?   ?   R . n 
E 5 162  LEU 162  -376 ?   ?   ?   R . n 
E 5 163  VAL 163  -375 ?   ?   ?   R . n 
E 5 164  GLN 164  -374 ?   ?   ?   R . n 
E 5 165  ASP 165  -373 ?   ?   ?   R . n 
E 5 166  PRO 166  -372 ?   ?   ?   R . n 
E 5 167  GLU 167  -371 ?   ?   ?   R . n 
E 5 168  THR 168  -370 ?   ?   ?   R . n 
E 5 169  LYS 169  -369 ?   ?   ?   R . n 
E 5 170  ARG 170  -368 ?   ?   ?   R . n 
E 5 171  ILE 171  -367 ?   ?   ?   R . n 
E 5 172  PHE 172  -366 ?   ?   ?   R . n 
E 5 173  SER 173  -365 ?   ?   ?   R . n 
E 5 174  ILE 174  -364 ?   ?   ?   R . n 
E 5 175  TYR 175  -363 ?   ?   ?   R . n 
E 5 176  ASP 176  -362 ?   ?   ?   R . n 
E 5 177  MET 177  -361 ?   ?   ?   R . n 
E 5 178  PHE 178  -360 ?   ?   ?   R . n 
E 5 179  PRO 179  -359 ?   ?   ?   R . n 
E 5 180  GLU 180  -358 ?   ?   ?   R . n 
E 5 181  GLY 181  -357 ?   ?   ?   R . n 
E 5 182  LYS 182  -356 ?   ?   ?   R . n 
E 5 183  GLY 183  -355 ?   ?   ?   R . n 
E 5 184  ILE 184  -354 ?   ?   ?   R . n 
E 5 185  PHE 185  -353 ?   ?   ?   R . n 
E 5 186  GLY 186  -352 ?   ?   ?   R . n 
E 5 187  MET 187  -351 ?   ?   ?   R . n 
E 5 188  SER 188  -350 ?   ?   ?   R . n 
E 5 189  SER 189  -349 ?   ?   ?   R . n 
E 5 190  GLN 190  -348 ?   ?   ?   R . n 
E 5 191  LYS 191  -347 ?   ?   ?   R . n 
E 5 192  GLU 192  -346 ?   ?   ?   R . n 
E 5 193  GLU 193  -345 ?   ?   ?   R . n 
E 5 194  ALA 194  -344 ?   ?   ?   R . n 
E 5 195  TYR 195  -343 ?   ?   ?   R . n 
E 5 196  LYS 196  -342 ?   ?   ?   R . n 
E 5 197  LYS 197  -341 ?   ?   ?   R . n 
E 5 198  ILE 198  -340 ?   ?   ?   R . n 
E 5 199  ASP 199  -339 ?   ?   ?   R . n 
E 5 200  GLY 200  -338 ?   ?   ?   R . n 
E 5 201  LYS 201  -337 ?   ?   ?   R . n 
E 5 202  THR 202  -336 ?   ?   ?   R . n 
E 5 203  TYR 203  -335 ?   ?   ?   R . n 
E 5 204  GLN 204  -334 ?   ?   ?   R . n 
E 5 205  ILE 205  -333 ?   ?   ?   R . n 
E 5 206  LEU 206  -332 ?   ?   ?   R . n 
E 5 207  TYR 207  -331 ?   ?   ?   R . n 
E 5 208  ARG 208  -330 ?   ?   ?   R . n 
E 5 209  GLU 209  -329 ?   ?   ?   R . n 
E 5 210  GLY 210  -328 ?   ?   ?   R . n 
E 5 211  GLU 211  -327 ?   ?   ?   R . n 
E 5 212  LYS 212  -326 ?   ?   ?   R . n 
E 5 213  GLY 213  -325 ?   ?   ?   R . n 
E 5 214  ALA 214  -324 ?   ?   ?   R . n 
E 5 215  TYR 215  -323 ?   ?   ?   R . n 
E 5 216  THR 216  -322 ?   ?   ?   R . n 
E 5 217  ILE 217  -321 ?   ?   ?   R . n 
E 5 218  ARG 218  -320 ?   ?   ?   R . n 
E 5 219  GLU 219  -319 ?   ?   ?   R . n 
E 5 220  ASN 220  -318 ?   ?   ?   R . n 
E 5 221  GLY 221  -317 ?   ?   ?   R . n 
E 5 222  THR 222  -316 ?   ?   ?   R . n 
E 5 223  VAL 223  -315 ?   ?   ?   R . n 
E 5 224  TYR 224  -314 ?   ?   ?   R . n 
E 5 225  THR 225  -313 ?   ?   ?   R . n 
E 5 226  PRO 226  -312 ?   ?   ?   R . n 
E 5 227  ASP 227  -311 ?   ?   ?   R . n 
E 5 228  GLY 228  -310 ?   ?   ?   R . n 
E 5 229  LYS 229  -309 ?   ?   ?   R . n 
E 5 230  ALA 230  -308 ?   ?   ?   R . n 
E 5 231  THR 231  -307 ?   ?   ?   R . n 
E 5 232  ASP 232  -306 ?   ?   ?   R . n 
E 5 233  TYR 233  -305 ?   ?   ?   R . n 
E 5 234  ARG 234  -304 ?   ?   ?   R . n 
E 5 235  VAL 235  -303 ?   ?   ?   R . n 
E 5 236  VAL 236  -302 ?   ?   ?   R . n 
E 5 237  VAL 237  -301 ?   ?   ?   R . n 
E 5 238  ASP 238  -300 ?   ?   ?   R . n 
E 5 239  PRO 239  -299 ?   ?   ?   R . n 
E 5 240  VAL 240  -298 ?   ?   ?   R . n 
E 5 241  LYS 241  -297 ?   ?   ?   R . n 
E 5 242  PRO 242  -296 ?   ?   ?   R . n 
E 5 243  ALA 243  -295 ?   ?   ?   R . n 
E 5 244  TYR 244  -294 ?   ?   ?   R . n 
E 5 245  SER 245  -293 ?   ?   ?   R . n 
E 5 246  ASP 246  -292 ?   ?   ?   R . n 
E 5 247  LYS 247  -291 ?   ?   ?   R . n 
E 5 248  GLY 248  -290 ?   ?   ?   R . n 
E 5 249  ASP 249  -289 ?   ?   ?   R . n 
E 5 250  LEU 250  -288 ?   ?   ?   R . n 
E 5 251  TYR 251  -287 ?   ?   ?   R . n 
E 5 252  LYS 252  -286 ?   ?   ?   R . n 
E 5 253  GLY 253  -285 ?   ?   ?   R . n 
E 5 254  ASP 254  -284 ?   ?   ?   R . n 
E 5 255  GLN 255  -283 ?   ?   ?   R . n 
E 5 256  LEU 256  -282 ?   ?   ?   R . n 
E 5 257  LEU 257  -281 ?   ?   ?   R . n 
E 5 258  GLY 258  -280 ?   ?   ?   R . n 
E 5 259  ASN 259  -279 ?   ?   ?   R . n 
E 5 260  ILE 260  -278 ?   ?   ?   R . n 
E 5 261  TYR 261  -277 ?   ?   ?   R . n 
E 5 262  PHE 262  -276 ?   ?   ?   R . n 
E 5 263  THR 263  -275 ?   ?   ?   R . n 
E 5 264  THR 264  -274 ?   ?   ?   R . n 
E 5 265  ASN 265  -273 ?   ?   ?   R . n 
E 5 266  LYS 266  -272 ?   ?   ?   R . n 
E 5 267  THR 267  -271 ?   ?   ?   R . n 
E 5 268  SER 268  -270 ?   ?   ?   R . n 
E 5 269  PRO 269  -269 ?   ?   ?   R . n 
E 5 270  PHE 270  -268 ?   ?   ?   R . n 
E 5 271  ARG 271  -267 ?   ?   ?   R . n 
E 5 272  ILE 272  -266 ?   ?   ?   R . n 
E 5 273  ALA 273  -265 ?   ?   ?   R . n 
E 5 274  LYS 274  -264 ?   ?   ?   R . n 
E 5 275  ASP 275  -263 ?   ?   ?   R . n 
E 5 276  SER 276  -262 ?   ?   ?   R . n 
E 5 277  TYR 277  -261 ?   ?   ?   R . n 
E 5 278  LEU 278  -260 ?   ?   ?   R . n 
E 5 279  TRP 279  -259 ?   ?   ?   R . n 
E 5 280  MET 280  -258 ?   ?   ?   R . n 
E 5 281  SER 281  -257 ?   ?   ?   R . n 
E 5 282  TYR 282  -256 ?   ?   ?   R . n 
E 5 283  SER 283  -255 ?   ?   ?   R . n 
E 5 284  ASP 284  -254 ?   ?   ?   R . n 
E 5 285  ASP 285  -253 ?   ?   ?   R . n 
E 5 286  ASP 286  -252 ?   ?   ?   R . n 
E 5 287  GLY 287  -251 ?   ?   ?   R . n 
E 5 288  LYS 288  -250 ?   ?   ?   R . n 
E 5 289  THR 289  -249 ?   ?   ?   R . n 
E 5 290  TRP 290  -248 ?   ?   ?   R . n 
E 5 291  SER 291  -247 ?   ?   ?   R . n 
E 5 292  ALA 292  -246 ?   ?   ?   R . n 
E 5 293  PRO 293  -245 ?   ?   ?   R . n 
E 5 294  GLN 294  -244 ?   ?   ?   R . n 
E 5 295  ASP 295  -243 ?   ?   ?   R . n 
E 5 296  ILE 296  -242 ?   ?   ?   R . n 
E 5 297  THR 297  -241 ?   ?   ?   R . n 
E 5 298  PRO 298  -240 ?   ?   ?   R . n 
E 5 299  MET 299  -239 ?   ?   ?   R . n 
E 5 300  VAL 300  -238 ?   ?   ?   R . n 
E 5 301  LYS 301  -237 ?   ?   ?   R . n 
E 5 302  ALA 302  -236 ?   ?   ?   R . n 
E 5 303  ASP 303  -235 ?   ?   ?   R . n 
E 5 304  TRP 304  -234 ?   ?   ?   R . n 
E 5 305  MET 305  -233 ?   ?   ?   R . n 
E 5 306  LYS 306  -232 ?   ?   ?   R . n 
E 5 307  PHE 307  -231 ?   ?   ?   R . n 
E 5 308  LEU 308  -230 ?   ?   ?   R . n 
E 5 309  GLY 309  -229 ?   ?   ?   R . n 
E 5 310  VAL 310  -228 ?   ?   ?   R . n 
E 5 311  GLY 311  -227 ?   ?   ?   R . n 
E 5 312  PRO 312  -226 ?   ?   ?   R . n 
E 5 313  GLY 313  -225 ?   ?   ?   R . n 
E 5 314  THR 314  -224 ?   ?   ?   R . n 
E 5 315  GLY 315  -223 ?   ?   ?   R . n 
E 5 316  ILE 316  -222 ?   ?   ?   R . n 
E 5 317  VAL 317  -221 ?   ?   ?   R . n 
E 5 318  LEU 318  -220 ?   ?   ?   R . n 
E 5 319  ARG 319  -219 ?   ?   ?   R . n 
E 5 320  ASN 320  -218 ?   ?   ?   R . n 
E 5 321  GLY 321  -217 ?   ?   ?   R . n 
E 5 322  PRO 322  -216 ?   ?   ?   R . n 
E 5 323  HIS 323  -215 ?   ?   ?   R . n 
E 5 324  LYS 324  -214 ?   ?   ?   R . n 
E 5 325  GLY 325  -213 ?   ?   ?   R . n 
E 5 326  ARG 326  -212 ?   ?   ?   R . n 
E 5 327  ILE 327  -211 ?   ?   ?   R . n 
E 5 328  LEU 328  -210 ?   ?   ?   R . n 
E 5 329  ILE 329  -209 ?   ?   ?   R . n 
E 5 330  PRO 330  -208 ?   ?   ?   R . n 
E 5 331  VAL 331  -207 ?   ?   ?   R . n 
E 5 332  TYR 332  -206 ?   ?   ?   R . n 
E 5 333  THR 333  -205 ?   ?   ?   R . n 
E 5 334  THR 334  -204 ?   ?   ?   R . n 
E 5 335  ASN 335  -203 ?   ?   ?   R . n 
E 5 336  ASN 336  -202 ?   ?   ?   R . n 
E 5 337  VAL 337  -201 ?   ?   ?   R . n 
E 5 338  SER 338  -200 ?   ?   ?   R . n 
E 5 339  HIS 339  -199 ?   ?   ?   R . n 
E 5 340  LEU 340  -198 ?   ?   ?   R . n 
E 5 341  ASP 341  -197 ?   ?   ?   R . n 
E 5 342  GLY 342  -196 ?   ?   ?   R . n 
E 5 343  SER 343  -195 ?   ?   ?   R . n 
E 5 344  GLN 344  -194 ?   ?   ?   R . n 
E 5 345  SER 345  -193 ?   ?   ?   R . n 
E 5 346  SER 346  -192 ?   ?   ?   R . n 
E 5 347  ARG 347  -191 ?   ?   ?   R . n 
E 5 348  VAL 348  -190 ?   ?   ?   R . n 
E 5 349  ILE 349  -189 ?   ?   ?   R . n 
E 5 350  TYR 350  -188 ?   ?   ?   R . n 
E 5 351  SER 351  -187 ?   ?   ?   R . n 
E 5 352  ASP 352  -186 ?   ?   ?   R . n 
E 5 353  ASP 353  -185 ?   ?   ?   R . n 
E 5 354  HIS 354  -184 ?   ?   ?   R . n 
E 5 355  GLY 355  -183 ?   ?   ?   R . n 
E 5 356  LYS 356  -182 ?   ?   ?   R . n 
E 5 357  THR 357  -181 ?   ?   ?   R . n 
E 5 358  TRP 358  -180 ?   ?   ?   R . n 
E 5 359  HIS 359  -179 ?   ?   ?   R . n 
E 5 360  ALA 360  -178 ?   ?   ?   R . n 
E 5 361  GLY 361  -177 ?   ?   ?   R . n 
E 5 362  GLU 362  -176 ?   ?   ?   R . n 
E 5 363  ALA 363  -175 ?   ?   ?   R . n 
E 5 364  VAL 364  -174 ?   ?   ?   R . n 
E 5 365  ASN 365  -173 ?   ?   ?   R . n 
E 5 366  ASP 366  -172 ?   ?   ?   R . n 
E 5 367  ASN 367  -171 ?   ?   ?   R . n 
E 5 368  ARG 368  -170 ?   ?   ?   R . n 
E 5 369  GLN 369  -169 ?   ?   ?   R . n 
E 5 370  VAL 370  -168 ?   ?   ?   R . n 
E 5 371  ASP 371  -167 ?   ?   ?   R . n 
E 5 372  GLY 372  -166 ?   ?   ?   R . n 
E 5 373  GLN 373  -165 ?   ?   ?   R . n 
E 5 374  LYS 374  -164 ?   ?   ?   R . n 
E 5 375  ILE 375  -163 ?   ?   ?   R . n 
E 5 376  HIS 376  -162 ?   ?   ?   R . n 
E 5 377  SER 377  -161 ?   ?   ?   R . n 
E 5 378  SER 378  -160 ?   ?   ?   R . n 
E 5 379  THR 379  -159 ?   ?   ?   R . n 
E 5 380  MET 380  -158 ?   ?   ?   R . n 
E 5 381  ASN 381  -157 ?   ?   ?   R . n 
E 5 382  ASN 382  -156 ?   ?   ?   R . n 
E 5 383  ARG 383  -155 ?   ?   ?   R . n 
E 5 384  ARG 384  -154 ?   ?   ?   R . n 
E 5 385  ALA 385  -153 ?   ?   ?   R . n 
E 5 386  GLN 386  -152 ?   ?   ?   R . n 
E 5 387  ASN 387  -151 ?   ?   ?   R . n 
E 5 388  THR 388  -150 ?   ?   ?   R . n 
E 5 389  GLU 389  -149 ?   ?   ?   R . n 
E 5 390  SER 390  -148 ?   ?   ?   R . n 
E 5 391  THR 391  -147 ?   ?   ?   R . n 
E 5 392  VAL 392  -146 ?   ?   ?   R . n 
E 5 393  VAL 393  -145 ?   ?   ?   R . n 
E 5 394  GLN 394  -144 ?   ?   ?   R . n 
E 5 395  LEU 395  -143 ?   ?   ?   R . n 
E 5 396  ASN 396  -142 ?   ?   ?   R . n 
E 5 397  ASN 397  -141 ?   ?   ?   R . n 
E 5 398  GLY 398  -140 ?   ?   ?   R . n 
E 5 399  ASP 399  -139 ?   ?   ?   R . n 
E 5 400  VAL 400  -138 ?   ?   ?   R . n 
E 5 401  LYS 401  -137 ?   ?   ?   R . n 
E 5 402  LEU 402  -136 ?   ?   ?   R . n 
E 5 403  PHE 403  -135 ?   ?   ?   R . n 
E 5 404  MET 404  -134 ?   ?   ?   R . n 
E 5 405  ARG 405  -133 ?   ?   ?   R . n 
E 5 406  GLY 406  -132 ?   ?   ?   R . n 
E 5 407  LEU 407  -131 ?   ?   ?   R . n 
E 5 408  THR 408  -130 ?   ?   ?   R . n 
E 5 409  GLY 409  -129 ?   ?   ?   R . n 
E 5 410  ASP 410  -128 ?   ?   ?   R . n 
E 5 411  LEU 411  -127 ?   ?   ?   R . n 
E 5 412  GLN 412  -126 ?   ?   ?   R . n 
E 5 413  VAL 413  -125 ?   ?   ?   R . n 
E 5 414  ALA 414  -124 ?   ?   ?   R . n 
E 5 415  THR 415  -123 ?   ?   ?   R . n 
E 5 416  SER 416  -122 ?   ?   ?   R . n 
E 5 417  LYS 417  -121 ?   ?   ?   R . n 
E 5 418  ASP 418  -120 ?   ?   ?   R . n 
E 5 419  GLY 419  -119 ?   ?   ?   R . n 
E 5 420  GLY 420  -118 ?   ?   ?   R . n 
E 5 421  VAL 421  -117 ?   ?   ?   R . n 
E 5 422  THR 422  -116 ?   ?   ?   R . n 
E 5 423  TRP 423  -115 ?   ?   ?   R . n 
E 5 424  GLU 424  -114 ?   ?   ?   R . n 
E 5 425  LYS 425  -113 ?   ?   ?   R . n 
E 5 426  ASP 426  -112 ?   ?   ?   R . n 
E 5 427  ILE 427  -111 ?   ?   ?   R . n 
E 5 428  LYS 428  -110 ?   ?   ?   R . n 
E 5 429  ARG 429  -109 ?   ?   ?   R . n 
E 5 430  TYR 430  -108 ?   ?   ?   R . n 
E 5 431  PRO 431  -107 ?   ?   ?   R . n 
E 5 432  GLN 432  -106 ?   ?   ?   R . n 
E 5 433  VAL 433  -105 ?   ?   ?   R . n 
E 5 434  LYS 434  -104 ?   ?   ?   R . n 
E 5 435  ASP 435  -103 ?   ?   ?   R . n 
E 5 436  VAL 436  -102 ?   ?   ?   R . n 
E 5 437  TYR 437  -101 ?   ?   ?   R . n 
E 5 438  VAL 438  -100 ?   ?   ?   R . n 
E 5 439  GLN 439  -99  ?   ?   ?   R . n 
E 5 440  MET 440  -98  ?   ?   ?   R . n 
E 5 441  SER 441  -97  ?   ?   ?   R . n 
E 5 442  ALA 442  -96  ?   ?   ?   R . n 
E 5 443  ILE 443  -95  ?   ?   ?   R . n 
E 5 444  HIS 444  -94  ?   ?   ?   R . n 
E 5 445  THR 445  -93  ?   ?   ?   R . n 
E 5 446  MET 446  -92  ?   ?   ?   R . n 
E 5 447  HIS 447  -91  ?   ?   ?   R . n 
E 5 448  GLU 448  -90  ?   ?   ?   R . n 
E 5 449  GLY 449  -89  ?   ?   ?   R . n 
E 5 450  LYS 450  -88  ?   ?   ?   R . n 
E 5 451  GLU 451  -87  ?   ?   ?   R . n 
E 5 452  TYR 452  -86  ?   ?   ?   R . n 
E 5 453  ILE 453  -85  ?   ?   ?   R . n 
E 5 454  ILE 454  -84  ?   ?   ?   R . n 
E 5 455  LEU 455  -83  ?   ?   ?   R . n 
E 5 456  SER 456  -82  ?   ?   ?   R . n 
E 5 457  ASN 457  -81  ?   ?   ?   R . n 
E 5 458  ALA 458  -80  ?   ?   ?   R . n 
E 5 459  GLY 459  -79  ?   ?   ?   R . n 
E 5 460  GLY 460  -78  ?   ?   ?   R . n 
E 5 461  PRO 461  -77  ?   ?   ?   R . n 
E 5 462  LYS 462  -76  ?   ?   ?   R . n 
E 5 463  ARG 463  -75  ?   ?   ?   R . n 
E 5 464  GLU 464  -74  ?   ?   ?   R . n 
E 5 465  ASN 465  -73  ?   ?   ?   R . n 
E 5 466  GLY 466  -72  ?   ?   ?   R . n 
E 5 467  MET 467  -71  ?   ?   ?   R . n 
E 5 468  VAL 468  -70  ?   ?   ?   R . n 
E 5 469  HIS 469  -69  ?   ?   ?   R . n 
E 5 470  LEU 470  -68  ?   ?   ?   R . n 
E 5 471  ALA 471  -67  ?   ?   ?   R . n 
E 5 472  ARG 472  -66  ?   ?   ?   R . n 
E 5 473  VAL 473  -65  ?   ?   ?   R . n 
E 5 474  GLU 474  -64  ?   ?   ?   R . n 
E 5 475  GLU 475  -63  ?   ?   ?   R . n 
E 5 476  ASN 476  -62  ?   ?   ?   R . n 
E 5 477  GLY 477  -61  ?   ?   ?   R . n 
E 5 478  GLU 478  -60  ?   ?   ?   R . n 
E 5 479  LEU 479  -59  ?   ?   ?   R . n 
E 5 480  THR 480  -58  ?   ?   ?   R . n 
E 5 481  TRP 481  -57  ?   ?   ?   R . n 
E 5 482  LEU 482  -56  ?   ?   ?   R . n 
E 5 483  LYS 483  -55  ?   ?   ?   R . n 
E 5 484  HIS 484  -54  ?   ?   ?   R . n 
E 5 485  ASN 485  -53  ?   ?   ?   R . n 
E 5 486  PRO 486  -52  ?   ?   ?   R . n 
E 5 487  ILE 487  -51  ?   ?   ?   R . n 
E 5 488  GLN 488  -50  ?   ?   ?   R . n 
E 5 489  LYS 489  -49  ?   ?   ?   R . n 
E 5 490  GLY 490  -48  ?   ?   ?   R . n 
E 5 491  GLU 491  -47  ?   ?   ?   R . n 
E 5 492  PHE 492  -46  ?   ?   ?   R . n 
E 5 493  ALA 493  -45  ?   ?   ?   R . n 
E 5 494  TYR 494  -44  ?   ?   ?   R . n 
E 5 495  ASN 495  -43  ?   ?   ?   R . n 
E 5 496  SER 496  -42  ?   ?   ?   R . n 
E 5 497  LEU 497  -41  ?   ?   ?   R . n 
E 5 498  GLN 498  -40  ?   ?   ?   R . n 
E 5 499  GLU 499  -39  ?   ?   ?   R . n 
E 5 500  LEU 500  -38  ?   ?   ?   R . n 
E 5 501  GLY 501  -37  ?   ?   ?   R . n 
E 5 502  ASN 502  -36  ?   ?   ?   R . n 
E 5 503  GLY 503  -35  ?   ?   ?   R . n 
E 5 504  GLU 504  -34  ?   ?   ?   R . n 
E 5 505  TYR 505  -33  ?   ?   ?   R . n 
E 5 506  GLY 506  -32  ?   ?   ?   R . n 
E 5 507  ILE 507  -31  ?   ?   ?   R . n 
E 5 508  LEU 508  -30  ?   ?   ?   R . n 
E 5 509  TYR 509  -29  ?   ?   ?   R . n 
E 5 510  GLU 510  -28  ?   ?   ?   R . n 
E 5 511  HIS 511  -27  ?   ?   ?   R . n 
E 5 512  THR 512  -26  ?   ?   ?   R . n 
E 5 513  GLU 513  -25  ?   ?   ?   R . n 
E 5 514  LYS 514  -24  ?   ?   ?   R . n 
E 5 515  GLY 515  -23  ?   ?   ?   R . n 
E 5 516  GLN 516  -22  ?   ?   ?   R . n 
E 5 517  ASN 517  -21  ?   ?   ?   R . n 
E 5 518  ALA 518  -20  ?   ?   ?   R . n 
E 5 519  TYR 519  -19  ?   ?   ?   R . n 
E 5 520  THR 520  -18  ?   ?   ?   R . n 
E 5 521  LEU 521  -17  ?   ?   ?   R . n 
E 5 522  SER 522  -16  ?   ?   ?   R . n 
E 5 523  PHE 523  -15  ?   ?   ?   R . n 
E 5 524  ARG 524  -14  ?   ?   ?   R . n 
E 5 525  LYS 525  -13  ?   ?   ?   R . n 
E 5 526  PHE 526  -12  ?   ?   ?   R . n 
E 5 527  ASN 527  -11  ?   ?   ?   R . n 
E 5 528  TRP 528  -10  ?   ?   ?   R . n 
E 5 529  GLU 529  -9   ?   ?   ?   R . n 
E 5 530  PHE 530  -8   ?   ?   ?   R . n 
E 5 531  LEU 531  -7   ?   ?   ?   R . n 
E 5 532  SER 532  -6   ?   ?   ?   R . n 
E 5 533  LYS 533  -5   ?   ?   ?   R . n 
E 5 534  ASN 534  -4   ?   ?   ?   R . n 
E 5 535  GLY 535  -3   ?   ?   ?   R . n 
E 5 536  SER 536  -2   ?   ?   ?   R . n 
E 5 537  GLY 537  -1   ?   ?   ?   R . n 
E 5 538  SER 538  0    ?   ?   ?   R . n 
E 5 539  GLY 539  1    ?   ?   ?   R . n 
E 5 540  ILE 540  2    2   ILE ILE R . n 
E 5 541  PRO 541  3    3   PRO PRO R . n 
E 5 542  ILE 542  4    4   ILE ILE R . n 
E 5 543  GLN 543  5    5   GLN GLN R . n 
E 5 544  LEU 544  6    6   LEU LEU R . n 
E 5 545  THR 545  7    7   THR THR R . n 
E 5 546  VAL 546  8    8   VAL VAL R . n 
E 5 547  PHE 547  9    9   PHE PHE R . n 
E 5 548  PHE 548  10   10  PHE PHE R . n 
E 5 549  MET 549  11   11  MET MET R . n 
E 5 550  ILE 550  12   12  ILE ILE R . n 
E 5 551  ILE 551  13   13  ILE ILE R . n 
E 5 552  TYR 552  14   14  TYR TYR R . n 
E 5 553  VAL 553  15   15  VAL VAL R . n 
E 5 554  LEU 554  16   16  LEU LEU R . n 
E 5 555  GLU 555  17   17  GLU GLU R . n 
E 5 556  SER 556  18   18  SER SER R . n 
E 5 557  LEU 557  19   19  LEU LEU R . n 
E 5 558  THR 558  20   20  THR THR R . n 
E 5 559  ILE 559  21   21  ILE ILE R . n 
E 5 560  ILE 560  22   22  ILE ILE R . n 
E 5 561  VAL 561  23   23  VAL VAL R . n 
E 5 562  GLN 562  24   24  GLN GLN R . n 
E 5 563  SER 563  25   25  SER SER R . n 
E 5 564  SER 564  26   26  SER SER R . n 
E 5 565  LEU 565  27   27  LEU LEU R . n 
E 5 566  ILE 566  28   28  ILE ILE R . n 
E 5 567  VAL 567  29   29  VAL VAL R . n 
E 5 568  ALA 568  30   30  ALA ALA R . n 
E 5 569  VAL 569  31   31  VAL VAL R . n 
E 5 570  LEU 570  32   32  LEU LEU R . n 
E 5 571  GLY 571  33   33  GLY GLY R . n 
E 5 572  ARG 572  34   34  ARG ARG R . n 
E 5 573  GLU 573  35   35  GLU GLU R . n 
E 5 574  TRP 574  36   36  TRP TRP R . n 
E 5 575  LEU 575  37   37  LEU LEU R . n 
E 5 576  GLN 576  38   38  GLN GLN R . n 
E 5 577  VAL 577  39   39  VAL VAL R . n 
E 5 578  ARG 578  40   40  ARG ARG R . n 
E 5 579  ARG 579  41   41  ARG ARG R . n 
E 5 580  LEU 580  42   42  LEU LEU R . n 
E 5 581  MET 581  43   43  MET MET R . n 
E 5 582  PRO 582  44   44  PRO PRO R . n 
E 5 583  VAL 583  45   45  VAL VAL R . n 
E 5 584  ASP 584  46   46  ASP ASP R . n 
E 5 585  MET 585  47   47  MET MET R . n 
E 5 586  ILE 586  48   48  ILE ILE R . n 
E 5 587  LEU 587  49   49  LEU LEU R . n 
E 5 588  ILE 588  50   50  ILE ILE R . n 
E 5 589  SER 589  51   51  SER SER R . n 
E 5 590  LEU 590  52   52  LEU LEU R . n 
E 5 591  GLY 591  53   53  GLY GLY R . n 
E 5 592  ILE 592  54   54  ILE ILE R . n 
E 5 593  SER 593  55   55  SER SER R . n 
E 5 594  ARG 594  56   56  ARG ARG R . n 
E 5 595  PHE 595  57   57  PHE PHE R . n 
E 5 596  CYS 596  58   58  CYS CYS R . n 
E 5 597  LEU 597  59   59  LEU LEU R . n 
E 5 598  GLN 598  60   60  GLN GLN R . n 
E 5 599  TRP 599  61   61  TRP TRP R . n 
E 5 600  ALA 600  62   62  ALA ALA R . n 
E 5 601  SER 601  63   63  SER SER R . n 
E 5 602  MET 602  64   64  MET MET R . n 
E 5 603  LEU 603  65   65  LEU LEU R . n 
E 5 604  ASN 604  66   66  ASN ASN R . n 
E 5 605  ASN 605  67   67  ASN ASN R . n 
E 5 606  PHE 606  68   68  PHE PHE R . n 
E 5 607  CYS 607  69   69  CYS CYS R . n 
E 5 608  SER 608  70   70  SER SER R . n 
E 5 609  TYR 609  71   71  TYR TYR R . n 
E 5 610  PHE 610  72   72  PHE PHE R . n 
E 5 611  ASN 611  73   73  ASN ASN R . n 
E 5 612  LEU 612  74   74  LEU LEU R . n 
E 5 613  ASN 613  75   75  ASN ASN R . n 
E 5 614  TYR 614  76   76  TYR TYR R . n 
E 5 615  VAL 615  77   77  VAL VAL R . n 
E 5 616  LEU 616  78   78  LEU LEU R . n 
E 5 617  CYS 617  79   79  CYS CYS R . n 
E 5 618  ASN 618  80   80  ASN ASN R . n 
E 5 619  LEU 619  81   81  LEU LEU R . n 
E 5 620  THR 620  82   82  THR THR R . n 
E 5 621  ILE 621  83   83  ILE ILE R . n 
E 5 622  THR 622  84   84  THR THR R . n 
E 5 623  TRP 623  85   85  TRP TRP R . n 
E 5 624  GLU 624  86   86  GLU GLU R . n 
E 5 625  PHE 625  87   87  PHE PHE R . n 
E 5 626  PHE 626  88   88  PHE PHE R . n 
E 5 627  ASN 627  89   89  ASN ASN R . n 
E 5 628  ILE 628  90   90  ILE ILE R . n 
E 5 629  LEU 629  91   91  LEU LEU R . n 
E 5 630  THR 630  92   92  THR THR R . n 
E 5 631  PHE 631  93   93  PHE PHE R . n 
E 5 632  TRP 632  94   94  TRP TRP R . n 
E 5 633  LEU 633  95   95  LEU LEU R . n 
E 5 634  ASN 634  96   96  ASN ASN R . n 
E 5 635  SER 635  97   97  SER SER R . n 
E 5 636  LEU 636  98   98  LEU LEU R . n 
E 5 637  LEU 637  99   99  LEU LEU R . n 
E 5 638  THR 638  100  100 THR THR R . n 
E 5 639  VAL 639  101  101 VAL VAL R . n 
E 5 640  PHE 640  102  102 PHE PHE R . n 
E 5 641  TYR 641  103  103 TYR TYR R . n 
E 5 642  CYS 642  104  104 CYS CYS R . n 
E 5 643  ILE 643  105  105 ILE ILE R . n 
E 5 644  LYS 644  106  106 LYS LYS R . n 
E 5 645  VAL 645  107  107 VAL VAL R . n 
E 5 646  SER 646  108  108 SER SER R . n 
E 5 647  SER 647  109  109 SER SER R . n 
E 5 648  PHE 648  110  110 PHE PHE R . n 
E 5 649  THR 649  111  111 THR THR R . n 
E 5 650  HIS 650  112  112 HIS HIS R . n 
E 5 651  HIS 651  113  113 HIS HIS R . n 
E 5 652  ILE 652  114  114 ILE ILE R . n 
E 5 653  PHE 653  115  115 PHE PHE R . n 
E 5 654  LEU 654  116  116 LEU LEU R . n 
E 5 655  TRP 655  117  117 TRP TRP R . n 
E 5 656  LEU 656  118  118 LEU LEU R . n 
E 5 657  ARG 657  119  119 ARG ARG R . n 
E 5 658  TRP 658  120  120 TRP TRP R . n 
E 5 659  ARG 659  121  121 ARG ARG R . n 
E 5 660  ILE 660  122  122 ILE ILE R . n 
E 5 661  LEU 661  123  123 LEU LEU R . n 
E 5 662  ARG 662  124  124 ARG ARG R . n 
E 5 663  LEU 663  125  125 LEU LEU R . n 
E 5 664  PHE 664  126  126 PHE PHE R . n 
E 5 665  PRO 665  127  127 PRO PRO R . n 
E 5 666  TRP 666  128  128 TRP TRP R . n 
E 5 667  ILE 667  129  129 ILE ILE R . n 
E 5 668  LEU 668  130  130 LEU LEU R . n 
E 5 669  LEU 669  131  131 LEU LEU R . n 
E 5 670  GLY 670  132  132 GLY GLY R . n 
E 5 671  CYS 671  133  133 CYS CYS R . n 
E 5 672  LEU 672  134  134 LEU LEU R . n 
E 5 673  MET 673  135  135 MET MET R . n 
E 5 674  ILE 674  136  136 ILE ILE R . n 
E 5 675  THR 675  137  137 THR THR R . n 
E 5 676  CYS 676  138  138 CYS CYS R . n 
E 5 677  VAL 677  139  139 VAL VAL R . n 
E 5 678  THR 678  140  140 THR THR R . n 
E 5 679  ILE 679  141  141 ILE ILE R . n 
E 5 680  ILE 680  142  142 ILE ILE R . n 
E 5 681  PRO 681  143  143 PRO PRO R . n 
E 5 682  SER 682  144  144 SER SER R . n 
E 5 683  ALA 683  145  145 ALA ALA R . n 
E 5 684  ILE 684  146  146 ILE ILE R . n 
E 5 685  GLY 685  147  147 GLY GLY R . n 
E 5 686  ASN 686  148  148 ASN ASN R . n 
E 5 687  TYR 687  149  149 TYR TYR R . n 
E 5 688  ILE 688  150  150 ILE ILE R . n 
E 5 689  GLN 689  151  151 GLN GLN R . n 
E 5 690  ILE 690  152  152 ILE ILE R . n 
E 5 691  GLN 691  153  153 GLN GLN R . n 
E 5 692  LEU 692  154  154 LEU LEU R . n 
E 5 693  LEU 693  155  155 LEU LEU R . n 
E 5 694  THR 694  156  ?   ?   ?   R . n 
E 5 695  MET 695  157  ?   ?   ?   R . n 
E 5 696  GLU 696  158  ?   ?   ?   R . n 
E 5 697  HIS 697  159  ?   ?   ?   R . n 
E 5 698  LEU 698  160  ?   ?   ?   R . n 
E 5 699  PRO 699  161  ?   ?   ?   R . n 
E 5 700  ARG 700  162  ?   ?   ?   R . n 
E 5 701  ASN 701  163  ?   ?   ?   R . n 
E 5 702  SER 702  164  ?   ?   ?   R . n 
E 5 703  THR 703  165  ?   ?   ?   R . n 
E 5 704  VAL 704  166  ?   ?   ?   R . n 
E 5 705  THR 705  167  ?   ?   ?   R . n 
E 5 706  ASP 706  168  ?   ?   ?   R . n 
E 5 707  LYS 707  169  ?   ?   ?   R . n 
E 5 708  LEU 708  170  ?   ?   ?   R . n 
E 5 709  GLU 709  171  171 GLU GLU R . n 
E 5 710  ASN 710  172  172 ASN ASN R . n 
E 5 711  PHE 711  173  173 PHE PHE R . n 
E 5 712  HIS 712  174  174 HIS HIS R . n 
E 5 713  GLN 713  175  175 GLN GLN R . n 
E 5 714  TYR 714  176  176 TYR TYR R . n 
E 5 715  GLN 715  177  177 GLN GLN R . n 
E 5 716  PHE 716  178  178 PHE PHE R . n 
E 5 717  GLN 717  179  179 GLN GLN R . n 
E 5 718  ALA 718  180  180 ALA ALA R . n 
E 5 719  HIS 719  181  181 HIS HIS R . n 
E 5 720  THR 720  182  182 THR THR R . n 
E 5 721  VAL 721  183  183 VAL VAL R . n 
E 5 722  ALA 722  184  184 ALA ALA R . n 
E 5 723  LEU 723  185  185 LEU LEU R . n 
E 5 724  VAL 724  186  186 VAL VAL R . n 
E 5 725  ILE 725  187  187 ILE ILE R . n 
E 5 726  PRO 726  188  188 PRO PRO R . n 
E 5 727  PHE 727  189  189 PHE PHE R . n 
E 5 728  ILE 728  190  190 ILE ILE R . n 
E 5 729  LEU 729  191  191 LEU LEU R . n 
E 5 730  PHE 730  192  192 PHE PHE R . n 
E 5 731  LEU 731  193  193 LEU LEU R . n 
E 5 732  ALA 732  194  194 ALA ALA R . n 
E 5 733  SER 733  195  195 SER SER R . n 
E 5 734  THR 734  196  196 THR THR R . n 
E 5 735  ILE 735  197  197 ILE ILE R . n 
E 5 736  PHE 736  198  198 PHE PHE R . n 
E 5 737  LEU 737  199  199 LEU LEU R . n 
E 5 738  MET 738  200  200 MET MET R . n 
E 5 739  ALA 739  201  201 ALA ALA R . n 
E 5 740  SER 740  202  202 SER SER R . n 
E 5 741  LEU 741  203  203 LEU LEU R . n 
E 5 742  THR 742  204  204 THR THR R . n 
E 5 743  LYS 743  205  205 LYS LYS R . n 
E 5 744  GLN 744  206  206 GLN GLN R . n 
E 5 745  ILE 745  207  207 ILE ILE R . n 
E 5 746  GLN 746  208  208 GLN GLN R . n 
E 5 747  HIS 747  209  209 HIS HIS R . n 
E 5 748  HIS 748  210  210 HIS HIS R . n 
E 5 749  SER 749  211  211 SER SER R . n 
E 5 750  THR 750  212  212 THR THR R . n 
E 5 751  GLY 751  213  213 GLY GLY R . n 
E 5 752  HIS 752  214  214 HIS HIS R . n 
E 5 753  CYS 753  215  215 CYS CYS R . n 
E 5 754  ASN 754  216  216 ASN ASN R . n 
E 5 755  PRO 755  217  217 PRO PRO R . n 
E 5 756  SER 756  218  218 SER SER R . n 
E 5 757  MET 757  219  219 MET MET R . n 
E 5 758  LYS 758  220  220 LYS LYS R . n 
E 5 759  ALA 759  221  221 ALA ALA R . n 
E 5 760  ARG 760  222  222 ARG ARG R . n 
E 5 761  PHE 761  223  223 PHE PHE R . n 
E 5 762  THR 762  224  224 THR THR R . n 
E 5 763  ALA 763  225  225 ALA ALA R . n 
E 5 764  LEU 764  226  226 LEU LEU R . n 
E 5 765  ARG 765  227  227 ARG ARG R . n 
E 5 766  SER 766  228  228 SER SER R . n 
E 5 767  LEU 767  229  229 LEU LEU R . n 
E 5 768  ALA 768  230  230 ALA ALA R . n 
E 5 769  VAL 769  231  231 VAL VAL R . n 
E 5 770  LEU 770  232  232 LEU LEU R . n 
E 5 771  PHE 771  233  233 PHE PHE R . n 
E 5 772  ILE 772  234  234 ILE ILE R . n 
E 5 773  VAL 773  235  235 VAL VAL R . n 
E 5 774  PHE 774  236  236 PHE PHE R . n 
E 5 775  THR 775  237  237 THR THR R . n 
E 5 776  SER 776  238  238 SER SER R . n 
E 5 777  TYR 777  239  239 TYR TYR R . n 
E 5 778  PHE 778  240  240 PHE PHE R . n 
E 5 779  LEU 779  241  241 LEU LEU R . n 
E 5 780  THR 780  242  242 THR THR R . n 
E 5 781  ILE 781  243  243 ILE ILE R . n 
E 5 782  LEU 782  244  244 LEU LEU R . n 
E 5 783  ILE 783  245  245 ILE ILE R . n 
E 5 784  THR 784  246  246 THR THR R . n 
E 5 785  ILE 785  247  247 ILE ILE R . n 
E 5 786  ILE 786  248  248 ILE ILE R . n 
E 5 787  GLY 787  249  249 GLY GLY R . n 
E 5 788  THR 788  250  250 THR THR R . n 
E 5 789  LEU 789  251  251 LEU LEU R . n 
E 5 790  PHE 790  252  252 PHE PHE R . n 
E 5 791  ASP 791  253  253 ASP ASP R . n 
E 5 792  LYS 792  254  254 LYS LYS R . n 
E 5 793  ARG 793  255  255 ARG ARG R . n 
E 5 794  CYS 794  256  256 CYS CYS R . n 
E 5 795  TRP 795  257  257 TRP TRP R . n 
E 5 796  LEU 796  258  258 LEU LEU R . n 
E 5 797  TRP 797  259  259 TRP TRP R . n 
E 5 798  VAL 798  260  260 VAL VAL R . n 
E 5 799  TRP 799  261  261 TRP TRP R . n 
E 5 800  GLU 800  262  262 GLU GLU R . n 
E 5 801  ALA 801  263  263 ALA ALA R . n 
E 5 802  PHE 802  264  264 PHE PHE R . n 
E 5 803  VAL 803  265  265 VAL VAL R . n 
E 5 804  TYR 804  266  266 TYR TYR R . n 
E 5 805  ALA 805  267  267 ALA ALA R . n 
E 5 806  PHE 806  268  268 PHE PHE R . n 
E 5 807  ILE 807  269  269 ILE ILE R . n 
E 5 808  LEU 808  270  270 LEU LEU R . n 
E 5 809  MET 809  271  271 MET MET R . n 
E 5 810  HIS 810  272  272 HIS HIS R . n 
E 5 811  SER 811  273  273 SER SER R . n 
E 5 812  THR 812  274  274 THR THR R . n 
E 5 813  SER 813  275  275 SER SER R . n 
E 5 814  LEU 814  276  276 LEU LEU R . n 
E 5 815  MET 815  277  277 MET MET R . n 
E 5 816  LEU 816  278  278 LEU LEU R . n 
E 5 817  SER 817  279  279 SER SER R . n 
E 5 818  SER 818  280  280 SER SER R . n 
E 5 819  PRO 819  281  281 PRO PRO R . n 
E 5 820  THR 820  282  282 THR THR R . n 
E 5 821  LEU 821  283  283 LEU LEU R . n 
E 5 822  LYS 822  284  284 LYS LYS R . n 
E 5 823  ARG 823  285  285 ARG ARG R . n 
E 5 824  ILE 824  286  286 ILE ILE R . n 
E 5 825  LEU 825  287  287 LEU LEU R . n 
E 5 826  LYS 826  288  ?   ?   ?   R . n 
E 5 827  GLY 827  289  ?   ?   ?   R . n 
E 5 828  LYS 828  290  ?   ?   ?   R . n 
E 5 829  CYS 829  291  ?   ?   ?   R . n 
E 5 830  GLY 830  292  ?   ?   ?   R . n 
E 5 831  SER 831  293  ?   ?   ?   R . n 
E 5 832  GLY 832  294  ?   ?   ?   R . n 
E 5 833  SER 833  295  ?   ?   ?   R . n 
E 5 834  GLY 834  296  ?   ?   ?   R . n 
E 5 835  GLY 835  297  ?   ?   ?   R . n 
E 5 836  SER 836  298  ?   ?   ?   R . n 
E 5 837  GLY 837  299  ?   ?   ?   R . n 
E 5 838  SER 838  300  ?   ?   ?   R . n 
E 5 839  GLY 839  301  ?   ?   ?   R . n 
E 5 840  GLY 840  302  ?   ?   ?   R . n 
E 5 841  SER 841  303  ?   ?   ?   R . n 
E 5 842  GLY 842  304  ?   ?   ?   R . n 
E 5 843  SER 843  305  ?   ?   ?   R . n 
E 5 844  GLY 844  306  ?   ?   ?   R . n 
E 5 845  GLY 845  307  ?   ?   ?   R . n 
E 5 846  SER 846  308  ?   ?   ?   R . n 
E 5 847  GLY 847  309  ?   ?   ?   R . n 
E 5 848  SER 848  310  ?   ?   ?   R . n 
E 5 849  GLY 849  311  ?   ?   ?   R . n 
E 5 850  SER 850  312  ?   ?   ?   R . n 
E 5 851  SER 851  313  ?   ?   ?   R . n 
E 5 852  GLY 852  314  ?   ?   ?   R . n 
E 5 853  GLY 853  315  ?   ?   ?   R . n 
E 5 854  VAL 854  316  ?   ?   ?   R . n 
E 5 855  PHE 855  317  ?   ?   ?   R . n 
E 5 856  THR 856  318  ?   ?   ?   R . n 
E 5 857  LEU 857  319  ?   ?   ?   R . n 
E 5 858  GLU 858  320  ?   ?   ?   R . n 
E 5 859  ASP 859  321  ?   ?   ?   R . n 
E 5 860  PHE 860  322  ?   ?   ?   R . n 
E 5 861  VAL 861  323  ?   ?   ?   R . n 
E 5 862  GLY 862  324  ?   ?   ?   R . n 
E 5 863  ASP 863  325  ?   ?   ?   R . n 
E 5 864  TRP 864  326  ?   ?   ?   R . n 
E 5 865  GLU 865  327  ?   ?   ?   R . n 
E 5 866  GLN 866  328  ?   ?   ?   R . n 
E 5 867  THR 867  329  ?   ?   ?   R . n 
E 5 868  ALA 868  330  ?   ?   ?   R . n 
E 5 869  ALA 869  331  ?   ?   ?   R . n 
E 5 870  TYR 870  332  ?   ?   ?   R . n 
E 5 871  ASN 871  333  ?   ?   ?   R . n 
E 5 872  LEU 872  334  ?   ?   ?   R . n 
E 5 873  ASP 873  335  ?   ?   ?   R . n 
E 5 874  GLN 874  336  ?   ?   ?   R . n 
E 5 875  VAL 875  337  ?   ?   ?   R . n 
E 5 876  LEU 876  338  ?   ?   ?   R . n 
E 5 877  GLU 877  339  ?   ?   ?   R . n 
E 5 878  GLN 878  340  ?   ?   ?   R . n 
E 5 879  GLY 879  341  ?   ?   ?   R . n 
E 5 880  GLY 880  342  ?   ?   ?   R . n 
E 5 881  VAL 881  343  ?   ?   ?   R . n 
E 5 882  SER 882  344  ?   ?   ?   R . n 
E 5 883  SER 883  345  ?   ?   ?   R . n 
E 5 884  LEU 884  346  ?   ?   ?   R . n 
E 5 885  LEU 885  347  ?   ?   ?   R . n 
E 5 886  GLN 886  348  ?   ?   ?   R . n 
E 5 887  ASN 887  349  ?   ?   ?   R . n 
E 5 888  LEU 888  350  ?   ?   ?   R . n 
E 5 889  ALA 889  351  ?   ?   ?   R . n 
E 5 890  VAL 890  352  ?   ?   ?   R . n 
E 5 891  SER 891  353  ?   ?   ?   R . n 
E 5 892  VAL 892  354  ?   ?   ?   R . n 
E 5 893  THR 893  355  ?   ?   ?   R . n 
E 5 894  PRO 894  356  ?   ?   ?   R . n 
E 5 895  ILE 895  357  ?   ?   ?   R . n 
E 5 896  GLN 896  358  ?   ?   ?   R . n 
E 5 897  ARG 897  359  ?   ?   ?   R . n 
E 5 898  ILE 898  360  ?   ?   ?   R . n 
E 5 899  VAL 899  361  ?   ?   ?   R . n 
E 5 900  ARG 900  362  ?   ?   ?   R . n 
E 5 901  SER 901  363  ?   ?   ?   R . n 
E 5 902  GLY 902  364  ?   ?   ?   R . n 
E 5 903  GLU 903  365  ?   ?   ?   R . n 
E 5 904  ASN 904  366  ?   ?   ?   R . n 
E 5 905  ALA 905  367  ?   ?   ?   R . n 
E 5 906  LEU 906  368  ?   ?   ?   R . n 
E 5 907  LYS 907  369  ?   ?   ?   R . n 
E 5 908  ILE 908  370  ?   ?   ?   R . n 
E 5 909  ASP 909  371  ?   ?   ?   R . n 
E 5 910  ILE 910  372  ?   ?   ?   R . n 
E 5 911  HIS 911  373  ?   ?   ?   R . n 
E 5 912  VAL 912  374  ?   ?   ?   R . n 
E 5 913  ILE 913  375  ?   ?   ?   R . n 
E 5 914  ILE 914  376  ?   ?   ?   R . n 
E 5 915  PRO 915  377  ?   ?   ?   R . n 
E 5 916  TYR 916  378  ?   ?   ?   R . n 
E 5 917  GLU 917  379  ?   ?   ?   R . n 
E 5 918  GLY 918  380  ?   ?   ?   R . n 
E 5 919  LEU 919  381  ?   ?   ?   R . n 
E 5 920  SER 920  382  ?   ?   ?   R . n 
E 5 921  ALA 921  383  ?   ?   ?   R . n 
E 5 922  ASP 922  384  ?   ?   ?   R . n 
E 5 923  GLN 923  385  ?   ?   ?   R . n 
E 5 924  MET 924  386  ?   ?   ?   R . n 
E 5 925  ALA 925  387  ?   ?   ?   R . n 
E 5 926  GLN 926  388  ?   ?   ?   R . n 
E 5 927  ILE 927  389  ?   ?   ?   R . n 
E 5 928  GLU 928  390  ?   ?   ?   R . n 
E 5 929  GLU 929  391  ?   ?   ?   R . n 
E 5 930  VAL 930  392  ?   ?   ?   R . n 
E 5 931  PHE 931  393  ?   ?   ?   R . n 
E 5 932  LYS 932  394  ?   ?   ?   R . n 
E 5 933  VAL 933  395  ?   ?   ?   R . n 
E 5 934  VAL 934  396  ?   ?   ?   R . n 
E 5 935  TYR 935  397  ?   ?   ?   R . n 
E 5 936  PRO 936  398  ?   ?   ?   R . n 
E 5 937  VAL 937  399  ?   ?   ?   R . n 
E 5 938  ASP 938  400  ?   ?   ?   R . n 
E 5 939  ASP 939  401  ?   ?   ?   R . n 
E 5 940  HIS 940  402  ?   ?   ?   R . n 
E 5 941  HIS 941  403  ?   ?   ?   R . n 
E 5 942  PHE 942  404  ?   ?   ?   R . n 
E 5 943  LYS 943  405  ?   ?   ?   R . n 
E 5 944  VAL 944  406  ?   ?   ?   R . n 
E 5 945  ILE 945  407  ?   ?   ?   R . n 
E 5 946  LEU 946  408  ?   ?   ?   R . n 
E 5 947  PRO 947  409  ?   ?   ?   R . n 
E 5 948  TYR 948  410  ?   ?   ?   R . n 
E 5 949  GLY 949  411  ?   ?   ?   R . n 
E 5 950  THR 950  412  ?   ?   ?   R . n 
E 5 951  LEU 951  413  ?   ?   ?   R . n 
E 5 952  VAL 952  414  ?   ?   ?   R . n 
E 5 953  ILE 953  415  ?   ?   ?   R . n 
E 5 954  ASP 954  416  ?   ?   ?   R . n 
E 5 955  GLY 955  417  ?   ?   ?   R . n 
E 5 956  VAL 956  418  ?   ?   ?   R . n 
E 5 957  THR 957  419  ?   ?   ?   R . n 
E 5 958  PRO 958  420  ?   ?   ?   R . n 
E 5 959  ASN 959  421  ?   ?   ?   R . n 
E 5 960  MET 960  422  ?   ?   ?   R . n 
E 5 961  LEU 961  423  ?   ?   ?   R . n 
E 5 962  ASN 962  424  ?   ?   ?   R . n 
E 5 963  TYR 963  425  ?   ?   ?   R . n 
E 5 964  PHE 964  426  ?   ?   ?   R . n 
E 5 965  GLY 965  427  ?   ?   ?   R . n 
E 5 966  ARG 966  428  ?   ?   ?   R . n 
E 5 967  PRO 967  429  ?   ?   ?   R . n 
E 5 968  TYR 968  430  ?   ?   ?   R . n 
E 5 969  GLU 969  431  ?   ?   ?   R . n 
E 5 970  GLY 970  432  ?   ?   ?   R . n 
E 5 971  ILE 971  433  ?   ?   ?   R . n 
E 5 972  ALA 972  434  ?   ?   ?   R . n 
E 5 973  VAL 973  435  ?   ?   ?   R . n 
E 5 974  PHE 974  436  ?   ?   ?   R . n 
E 5 975  ASP 975  437  ?   ?   ?   R . n 
E 5 976  GLY 976  438  ?   ?   ?   R . n 
E 5 977  LYS 977  439  ?   ?   ?   R . n 
E 5 978  LYS 978  440  ?   ?   ?   R . n 
E 5 979  ILE 979  441  ?   ?   ?   R . n 
E 5 980  THR 980  442  ?   ?   ?   R . n 
E 5 981  VAL 981  443  ?   ?   ?   R . n 
E 5 982  THR 982  444  ?   ?   ?   R . n 
E 5 983  GLY 983  445  ?   ?   ?   R . n 
E 5 984  THR 984  446  ?   ?   ?   R . n 
E 5 985  LEU 985  447  ?   ?   ?   R . n 
E 5 986  TRP 986  448  ?   ?   ?   R . n 
E 5 987  ASN 987  449  ?   ?   ?   R . n 
E 5 988  GLY 988  450  ?   ?   ?   R . n 
E 5 989  ASN 989  451  ?   ?   ?   R . n 
E 5 990  LYS 990  452  ?   ?   ?   R . n 
E 5 991  ILE 991  453  ?   ?   ?   R . n 
E 5 992  ILE 992  454  ?   ?   ?   R . n 
E 5 993  ASP 993  455  ?   ?   ?   R . n 
E 5 994  GLU 994  456  ?   ?   ?   R . n 
E 5 995  ARG 995  457  ?   ?   ?   R . n 
E 5 996  LEU 996  458  ?   ?   ?   R . n 
E 5 997  ILE 997  459  ?   ?   ?   R . n 
E 5 998  THR 998  460  ?   ?   ?   R . n 
E 5 999  PRO 999  461  ?   ?   ?   R . n 
E 5 1000 ASP 1000 462  ?   ?   ?   R . n 
E 5 1001 GLY 1001 463  ?   ?   ?   R . n 
E 5 1002 SER 1002 464  ?   ?   ?   R . n 
E 5 1003 MET 1003 465  ?   ?   ?   R . n 
E 5 1004 LEU 1004 466  ?   ?   ?   R . n 
E 5 1005 PHE 1005 467  ?   ?   ?   R . n 
E 5 1006 ARG 1006 468  ?   ?   ?   R . n 
E 5 1007 VAL 1007 469  ?   ?   ?   R . n 
E 5 1008 THR 1008 470  ?   ?   ?   R . n 
E 5 1009 ILE 1009 471  ?   ?   ?   R . n 
E 5 1010 ASN 1010 472  ?   ?   ?   R . n 
E 5 1011 SER 1011 473  ?   ?   ?   R . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        SA0 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   SA0 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         F 
_pdbx_nonpoly_scheme.entity_id       6 
_pdbx_nonpoly_scheme.mon_id          SA0 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     501 
_pdbx_nonpoly_scheme.auth_seq_num    301 
_pdbx_nonpoly_scheme.pdb_mon_id      SA0 
_pdbx_nonpoly_scheme.auth_mon_id     SA0 
_pdbx_nonpoly_scheme.pdb_strand_id   R 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9K6L 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9K6L 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9K6L 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9K6L 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.004 ? 9108  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.759 ? 12339 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 4.415 ? 1226  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.045 ? 1410  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005 ? 1542  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9K6L 
_struct.title                        'Cryo-EM structure of GPCR16-Gi2 complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9K6L 
_struct_keywords.text            'Tas2R16, GPCR, Gi2, Salicin, SIGNALING PROTEIN, SIGNALING PROTEIN-IMMUNE SYSTEM complex' 
_struct_keywords.pdbx_keywords   'SIGNALING PROTEIN/IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP GNAI2_HUMAN      P04899     ? 1 
;MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQYRAVVYSNTIQS
IMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDL
ERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEE
MNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFEDLNKRKDTKEI
YTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
1   
2 UNP GBB1_HUMAN       P62873     ? 2 
;MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLI
IWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS
SGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA
FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGV
TDDGMAVATGSWDSFLKIWN
;
1   
3 UNP GBG2_HUMAN       P59768     ? 3 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 1   
4 PDB 9K6L             9K6L       ? 4 ? 1   
5 UNP A0A4J2AMT3_STREE A0A4J2AMT3 ? 5 
;PEGAALTEKTDIFESGRNGNPNKDGIKSYRIPALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTIT
NLRDNPKASDPSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILYREGEKGAYTIRE
NGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTNKTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPM
VKADWMKFLGVGPGTGIVLRNGPHKGRILIPVYTTNNVSHLDGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSST
MNNRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQMSAIHTMHEGKEYIILSNAG
GPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSLQELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKN
;
303 
6 UNP T2R16_HUMAN      Q9NYV7     ? 5 
;IPIQLTVFFMIIYVLESLTIIVQSSLIVAVLGREWLQVRRLMPVDMILISLGISRFCLQWASMLNNFCSYFNLNYVLCNL
TITWEFFNILTFWLNSLLTVFYCIKVSSFTHHIFLWLRWRILRLFPWILLGSLMITCVTIIPSAIGNYIQIQLLTMEHLP
RNSTVTDKLENFHQYQFQAHTVALVIPFILFLASTIFLMASLTKQIQHHSTGHCNPSMKARFTALRSLAVLFIVFTSYFL
TILITIIGTLFDKRCWLWVWEAFVYAFILMHSTSLMLSSPTLKRILKGKC
;
2   
7 PDB 9K6L             9K6L       ? 5 ? 830 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9K6L A 1   ? 355  ? P04899     1   ? 355 ? 1    355 
2 2 9K6L B 1   ? 340  ? P62873     1   ? 340 ? 1    340 
3 3 9K6L G 1   ? 71   ? P59768     1   ? 71  ? 1    71  
4 4 9K6L S 1   ? 266  ? 9K6L       1   ? 254 ? 1    254 
5 5 9K6L R 60  ? 534  ? A0A4J2AMT3 303 ? 777 ? -478 -4  
6 6 9K6L R 540 ? 829  ? Q9NYV7     2   ? 291 ? 2    291 
7 7 9K6L R 830 ? 1011 ? 9K6L       292 ? 473 ? 292  473 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9K6L ASN A 47  ? UNP P04899     SER 47  'engineered mutation'   47   1  
1 9K6L ALA A 204 ? UNP P04899     GLY 204 'engineered mutation'   204  2  
1 9K6L SER A 327 ? UNP P04899     ALA 327 'engineered mutation'   327  3  
2 9K6L GLY B 341 ? UNP P62873     ?   ?   'expression tag'        341  4  
2 9K6L SER B 342 ? UNP P62873     ?   ?   'expression tag'        342  5  
2 9K6L SER B 343 ? UNP P62873     ?   ?   'expression tag'        343  6  
2 9K6L GLY B 344 ? UNP P62873     ?   ?   'expression tag'        344  7  
2 9K6L GLY B 345 ? UNP P62873     ?   ?   'expression tag'        345  8  
2 9K6L GLY B 346 ? UNP P62873     ?   ?   'expression tag'        346  9  
2 9K6L GLY B 347 ? UNP P62873     ?   ?   'expression tag'        347  10 
2 9K6L SER B 348 ? UNP P62873     ?   ?   'expression tag'        348  11 
2 9K6L GLY B 349 ? UNP P62873     ?   ?   'expression tag'        349  12 
2 9K6L GLY B 350 ? UNP P62873     ?   ?   'expression tag'        350  13 
2 9K6L GLY B 351 ? UNP P62873     ?   ?   'expression tag'        351  14 
2 9K6L GLY B 352 ? UNP P62873     ?   ?   'expression tag'        352  15 
2 9K6L SER B 353 ? UNP P62873     ?   ?   'expression tag'        353  16 
2 9K6L SER B 354 ? UNP P62873     ?   ?   'expression tag'        354  17 
2 9K6L GLY B 355 ? UNP P62873     ?   ?   'expression tag'        355  18 
2 9K6L VAL B 356 ? UNP P62873     ?   ?   'expression tag'        356  19 
2 9K6L SER B 357 ? UNP P62873     ?   ?   'expression tag'        357  20 
2 9K6L GLY B 358 ? UNP P62873     ?   ?   'expression tag'        358  21 
2 9K6L TRP B 359 ? UNP P62873     ?   ?   'expression tag'        359  22 
2 9K6L ARG B 360 ? UNP P62873     ?   ?   'expression tag'        360  23 
2 9K6L LEU B 361 ? UNP P62873     ?   ?   'expression tag'        361  24 
2 9K6L PHE B 362 ? UNP P62873     ?   ?   'expression tag'        362  25 
2 9K6L LYS B 363 ? UNP P62873     ?   ?   'expression tag'        363  26 
2 9K6L LYS B 364 ? UNP P62873     ?   ?   'expression tag'        364  27 
2 9K6L ILE B 365 ? UNP P62873     ?   ?   'expression tag'        365  28 
2 9K6L SER B 366 ? UNP P62873     ?   ?   'expression tag'        366  29 
5 9K6L MET R 1   ? UNP A0A4J2AMT3 ?   ?   'initiating methionine' -537 30 
5 9K6L LYS R 2   ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -536 31 
5 9K6L THR R 3   ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -535 32 
5 9K6L ILE R 4   ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -534 33 
5 9K6L ILE R 5   ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -533 34 
5 9K6L ALA R 6   ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -532 35 
5 9K6L LEU R 7   ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -531 36 
5 9K6L SER R 8   ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -530 37 
5 9K6L TYR R 9   ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -529 38 
5 9K6L ILE R 10  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -528 39 
5 9K6L PHE R 11  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -527 40 
5 9K6L CYS R 12  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -526 41 
5 9K6L LEU R 13  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -525 42 
5 9K6L VAL R 14  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -524 43 
5 9K6L PHE R 15  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -523 44 
5 9K6L ALA R 16  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -522 45 
5 9K6L ASP R 17  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -521 46 
5 9K6L TYR R 18  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -520 47 
5 9K6L LYS R 19  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -519 48 
5 9K6L ASP R 20  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -518 49 
5 9K6L ASP R 21  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -517 50 
5 9K6L ASP R 22  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -516 51 
5 9K6L ASP R 23  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -515 52 
5 9K6L ALA R 24  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -514 53 
5 9K6L HIS R 25  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -513 54 
5 9K6L HIS R 26  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -512 55 
5 9K6L HIS R 27  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -511 56 
5 9K6L HIS R 28  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -510 57 
5 9K6L HIS R 29  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -509 58 
5 9K6L HIS R 30  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -508 59 
5 9K6L HIS R 31  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -507 60 
5 9K6L HIS R 32  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -506 61 
5 9K6L HIS R 33  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -505 62 
5 9K6L HIS R 34  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -504 63 
5 9K6L GLU R 35  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -503 64 
5 9K6L ASN R 36  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -502 65 
5 9K6L LEU R 37  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -501 66 
5 9K6L TYR R 38  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -500 67 
5 9K6L PHE R 39  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -499 68 
5 9K6L GLN R 40  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -498 69 
5 9K6L SER R 41  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -497 70 
5 9K6L ALA R 42  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -496 71 
5 9K6L HIS R 43  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -495 72 
5 9K6L HIS R 44  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -494 73 
5 9K6L HIS R 45  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -493 74 
5 9K6L HIS R 46  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -492 75 
5 9K6L HIS R 47  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -491 76 
5 9K6L HIS R 48  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -490 77 
5 9K6L SER R 49  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -489 78 
5 9K6L SER R 50  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -488 79 
5 9K6L GLY R 51  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -487 80 
5 9K6L LEU R 52  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -486 81 
5 9K6L GLU R 53  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -485 82 
5 9K6L VAL R 54  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -484 83 
5 9K6L LEU R 55  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -483 84 
5 9K6L PHE R 56  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -482 85 
5 9K6L GLN R 57  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -481 86 
5 9K6L GLY R 58  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -480 87 
5 9K6L PRO R 59  ? UNP A0A4J2AMT3 ?   ?   'expression tag'        -479 88 
5 9K6L GLY R 535 ? UNP A0A4J2AMT3 ?   ?   linker                  -3   89 
5 9K6L SER R 536 ? UNP A0A4J2AMT3 ?   ?   linker                  -2   90 
5 9K6L GLY R 537 ? UNP A0A4J2AMT3 ?   ?   linker                  -1   91 
5 9K6L SER R 538 ? UNP A0A4J2AMT3 ?   ?   linker                  0    92 
5 9K6L GLY R 539 ? UNP A0A4J2AMT3 ?   ?   linker                  1    93 
6 9K6L CYS R 671 ? UNP Q9NYV7     SER 133 'engineered mutation'   133  94 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 6   ? ALA A 31  ? SER A 6   ALA A 31  1 ? 26 
HELX_P HELX_P2  AA2 GLY A 45  ? LYS A 54  ? GLY A 45  LYS A 54  1 ? 10 
HELX_P HELX_P3  AA3 GLU A 208 ? GLU A 217 ? GLU A 208 GLU A 217 5 ? 10 
HELX_P HELX_P4  AA4 SER A 229 ? ASP A 232 ? SER A 229 ASP A 232 5 ? 4  
HELX_P HELX_P5  AA5 ASN A 242 ? ASN A 256 ? ASN A 242 ASN A 256 1 ? 15 
HELX_P HELX_P6  AA6 LYS A 271 ? ILE A 279 ? LYS A 271 ILE A 279 1 ? 9  
HELX_P HELX_P7  AA7 LYS A 296 ? LEU A 311 ? LYS A 296 LEU A 311 1 ? 16 
HELX_P HELX_P8  AA8 THR A 330 ? CYS A 352 ? THR A 330 CYS A 352 1 ? 23 
HELX_P HELX_P9  AA9 LEU B 4   ? ALA B 26  ? LEU B 4   ALA B 26  1 ? 23 
HELX_P HELX_P10 AB1 THR B 29  ? THR B 34  ? THR B 29  THR B 34  1 ? 6  
HELX_P HELX_P11 AB2 ALA C 7   ? ASN C 24  ? ALA G 7   ASN G 24  1 ? 18 
HELX_P HELX_P12 AB3 LYS C 29  ? HIS C 44  ? LYS G 29  HIS G 44  1 ? 16 
HELX_P HELX_P13 AB4 SER D 53  ? GLY D 56  ? SER S 53  GLY S 56  5 ? 4  
HELX_P HELX_P14 AB5 ARG D 87  ? THR D 91  ? ARG S 87  THR S 91  5 ? 5  
HELX_P HELX_P15 AB6 GLU D 220 ? VAL D 224 ? GLU S 208 VAL S 212 5 ? 5  
HELX_P HELX_P16 AB7 PRO E 541 ? ARG E 578 ? PRO R 3   ARG R 40  1 ? 38 
HELX_P HELX_P17 AB8 MET E 581 ? ASN E 611 ? MET R 43  ASN R 73  1 ? 31 
HELX_P HELX_P18 AB9 LEU E 619 ? SER E 646 ? LEU R 81  SER R 108 1 ? 28 
HELX_P HELX_P19 AC1 HIS E 650 ? LEU E 663 ? HIS R 112 LEU R 125 1 ? 14 
HELX_P HELX_P20 AC2 LEU E 663 ? LEU E 693 ? LEU R 125 LEU R 155 1 ? 31 
HELX_P HELX_P21 AC3 ASN E 710 ? HIS E 748 ? ASN R 172 HIS R 210 1 ? 39 
HELX_P HELX_P22 AC4 CYS E 753 ? ILE E 786 ? CYS R 215 ILE R 248 1 ? 34 
HELX_P HELX_P23 AC5 GLY E 787 ? PHE E 790 ? GLY R 249 PHE R 252 5 ? 4  
HELX_P HELX_P24 AC6 TRP E 795 ? SER E 817 ? TRP R 257 SER R 279 1 ? 23 
HELX_P HELX_P25 AC7 SER E 818 ? LEU E 825 ? SER R 280 LEU R 287 1 ? 8  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? D CYS 22  SG ? ? ? 1_555 D CYS 96  SG ? ? S CYS 22  S CYS 96  1_555 ? ? ? ? ? ? ? 2.033 ? ? 
disulf2 disulf ? ? D CYS 159 SG ? ? ? 1_555 D CYS 229 SG ? ? S CYS 147 S CYS 217 1_555 ? ? ? ? ? ? ? 2.035 ? ? 
disulf3 disulf ? ? E CYS 607 SG ? ? ? 1_555 E CYS 617 SG ? ? R CYS 69  R CYS 79  1_555 ? ? ? ? ? ? ? 2.033 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS D 22  ? CYS D 96  ? CYS S 22  ? 1_555 CYS S 96  ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS D 159 ? CYS D 229 ? CYS S 147 ? 1_555 CYS S 217 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS E 607 ? CYS E 617 ? CYS R 69  ? 1_555 CYS R 79  ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 6 ? 
AB2 ? 4 ? 
AB3 ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? parallel      
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB3 4 5 ? anti-parallel 
AB3 5 6 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 186 ? THR A 191 ? VAL A 186 THR A 191 
AA1 2 HIS A 196 ? ASP A 201 ? HIS A 196 ASP A 201 
AA1 3 VAL A 34  ? GLY A 40  ? VAL A 34  GLY A 40  
AA1 4 ALA A 221 ? ALA A 227 ? ALA A 221 ALA A 227 
AA1 5 SER A 264 ? ASN A 270 ? SER A 264 ASN A 270 
AA1 6 ILE A 320 ? PHE A 324 ? ILE A 320 PHE A 324 
AA2 1 MET B 45  ? ARG B 52  ? MET B 45  ARG B 52  
AA2 2 PHE B 335 ? GLY B 341 ? PHE B 335 GLY B 341 
AA2 3 VAL B 327 ? SER B 331 ? VAL B 327 SER B 331 
AA2 4 VAL B 315 ? VAL B 320 ? VAL B 315 VAL B 320 
AA3 1 ILE B 58  ? TRP B 63  ? ILE B 58  TRP B 63  
AA3 2 LEU B 69  ? SER B 74  ? LEU B 69  SER B 74  
AA3 3 LYS B 78  ? ASP B 83  ? LYS B 78  ASP B 83  
AA3 4 LYS B 89  ? PRO B 94  ? LYS B 89  PRO B 94  
AA4 1 VAL B 100 ? TYR B 105 ? VAL B 100 TYR B 105 
AA4 2 TYR B 111 ? GLY B 116 ? TYR B 111 GLY B 116 
AA4 3 ILE B 120 ? ASN B 125 ? ILE B 120 ASN B 125 
AA4 4 ARG B 134 ? ALA B 140 ? ARG B 134 ALA B 140 
AA5 1 LEU B 146 ? PHE B 151 ? LEU B 146 PHE B 151 
AA5 2 GLN B 156 ? SER B 161 ? GLN B 156 SER B 161 
AA5 3 THR B 165 ? ASP B 170 ? THR B 165 ASP B 170 
AA5 4 GLN B 175 ? THR B 181 ? GLN B 175 THR B 181 
AA6 1 VAL B 187 ? LEU B 192 ? VAL B 187 LEU B 192 
AA6 2 LEU B 198 ? ALA B 203 ? LEU B 198 ALA B 203 
AA6 3 SER B 207 ? ASP B 212 ? SER B 207 ASP B 212 
AA6 4 CYS B 218 ? THR B 223 ? CYS B 218 THR B 223 
AA7 1 ILE B 229 ? PHE B 234 ? ILE B 229 PHE B 234 
AA7 2 ALA B 240 ? SER B 245 ? ALA B 240 SER B 245 
AA7 3 CYS B 250 ? ASP B 254 ? CYS B 250 ASP B 254 
AA7 4 GLU B 260 ? TYR B 264 ? GLU B 260 TYR B 264 
AA8 1 SER B 275 ? PHE B 278 ? SER B 275 PHE B 278 
AA8 2 LEU B 284 ? GLY B 288 ? LEU B 284 GLY B 288 
AA8 3 CYS B 294 ? ASP B 298 ? CYS B 294 ASP B 298 
AA8 4 ASP B 303 ? LEU B 308 ? ASP B 303 LEU B 308 
AA9 1 GLN D 3   ? SER D 7   ? GLN S 3   SER S 7   
AA9 2 SER D 17  ? SER D 25  ? SER S 17  SER S 25  
AA9 3 THR D 78  ? THR D 84  ? THR S 78  THR S 84  
AA9 4 PHE D 68  ? ASP D 73  ? PHE S 68  ASP S 73  
AB1 1 GLY D 10  ? VAL D 12  ? GLY S 10  VAL S 12  
AB1 2 THR D 115 ? VAL D 119 ? THR S 115 VAL S 119 
AB1 3 ALA D 92  ? SER D 99  ? ALA S 92  SER S 99  
AB1 4 GLY D 33  ? GLN D 39  ? GLY S 33  GLN S 39  
AB1 5 LEU D 45  ? ILE D 51  ? LEU S 45  ILE S 51  
AB1 6 ILE D 58  ? TYR D 60  ? ILE S 58  TYR S 60  
AB2 1 MET D 140 ? THR D 141 ? MET S 128 THR S 129 
AB2 2 VAL D 155 ? SER D 161 ? VAL S 143 SER S 149 
AB2 3 ALA D 211 ? ILE D 216 ? ALA S 199 ILE S 204 
AB2 4 PHE D 203 ? SER D 208 ? PHE S 191 SER S 196 
AB3 1 VAL D 147 ? PRO D 148 ? VAL S 135 PRO S 136 
AB3 2 THR D 243 ? GLU D 246 ? THR S 231 GLU S 234 
AB3 3 GLY D 225 ? GLN D 231 ? GLY S 213 GLN S 219 
AB3 4 LEU D 174 ? GLN D 179 ? LEU S 162 GLN S 167 
AB3 5 GLN D 186 ? TYR D 190 ? GLN S 174 TYR S 178 
AB3 6 ASN D 194 ? LEU D 195 ? ASN S 182 LEU S 183 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 186 ? N VAL A 186 O ASP A 201 ? O ASP A 201 
AA1 2 3 O LYS A 198 ? O LYS A 198 N LEU A 36  ? N LEU A 36  
AA1 3 4 N LEU A 37  ? N LEU A 37  O ALA A 221 ? O ALA A 221 
AA1 4 5 N VAL A 226 ? N VAL A 226 O PHE A 268 ? O PHE A 268 
AA1 5 6 N LEU A 269 ? N LEU A 269 O HIS A 323 ? O HIS A 323 
AA2 1 2 N LEU B 51  ? N LEU B 51  O LEU B 336 ? O LEU B 336 
AA2 2 3 O TRP B 339 ? O TRP B 339 N VAL B 327 ? N VAL B 327 
AA2 3 4 O GLY B 330 ? O GLY B 330 N CYS B 317 ? N CYS B 317 
AA3 1 2 N ALA B 60  ? N ALA B 60  O ALA B 73  ? O ALA B 73  
AA3 2 3 N LEU B 70  ? N LEU B 70  O TRP B 82  ? O TRP B 82  
AA3 3 4 N LEU B 79  ? N LEU B 79  O ILE B 93  ? O ILE B 93  
AA4 1 2 N ALA B 104 ? N ALA B 104 O ALA B 113 ? O ALA B 113 
AA4 2 3 N VAL B 112 ? N VAL B 112 O TYR B 124 ? O TYR B 124 
AA4 3 4 N CYS B 121 ? N CYS B 121 O LEU B 139 ? O LEU B 139 
AA5 1 2 N SER B 147 ? N SER B 147 O SER B 160 ? O SER B 160 
AA5 2 3 N ILE B 157 ? N ILE B 157 O TRP B 169 ? O TRP B 169 
AA5 3 4 N LEU B 168 ? N LEU B 168 O THR B 178 ? O THR B 178 
AA6 1 2 N SER B 191 ? N SER B 191 O VAL B 200 ? O VAL B 200 
AA6 2 3 N PHE B 199 ? N PHE B 199 O TRP B 211 ? O TRP B 211 
AA6 3 4 N ALA B 208 ? N ALA B 208 O PHE B 222 ? O PHE B 222 
AA7 1 2 N CYS B 233 ? N CYS B 233 O ALA B 242 ? O ALA B 242 
AA7 2 3 N PHE B 241 ? N PHE B 241 O PHE B 253 ? O PHE B 253 
AA7 3 4 N LEU B 252 ? N LEU B 252 O LEU B 261 ? O LEU B 261 
AA8 1 2 N SER B 277 ? N SER B 277 O LEU B 286 ? O LEU B 286 
AA8 2 3 N LEU B 285 ? N LEU B 285 O TRP B 297 ? O TRP B 297 
AA8 3 4 N CYS B 294 ? N CYS B 294 O LEU B 308 ? O LEU B 308 
AA9 1 2 N GLN D 3   ? N GLN S 3   O SER D 25  ? O SER S 25  
AA9 2 3 N CYS D 22  ? N CYS S 22  O LEU D 79  ? O LEU S 79  
AA9 3 4 O THR D 78  ? O THR S 78  N ASP D 73  ? N ASP S 73  
AB1 1 2 N GLY D 10  ? N GLY S 10  O THR D 118 ? O THR S 118 
AB1 2 3 O LEU D 117 ? O LEU S 117 N ALA D 92  ? N ALA S 92  
AB1 3 4 O MET D 93  ? O MET S 93  N GLN D 39  ? N GLN S 39  
AB1 4 5 N ARG D 38  ? N ARG S 38  O GLU D 46  ? O GLU S 46  
AB1 5 6 N TYR D 50  ? N TYR S 50  O TYR D 59  ? O TYR S 59  
AB2 1 2 N THR D 141 ? N THR S 129 O ARG D 160 ? O ARG S 148 
AB2 2 3 N CYS D 159 ? N CYS S 147 O PHE D 212 ? O PHE S 200 
AB2 3 4 O THR D 213 ? O THR S 201 N SER D 206 ? N SER S 194 
AB3 1 2 N VAL D 147 ? N VAL S 135 O LYS D 244 ? O LYS S 232 
AB3 2 3 O LEU D 245 ? O LEU S 233 N GLY D 225 ? N GLY S 213 
AB3 3 4 O VAL D 226 ? O VAL S 214 N GLN D 179 ? N GLN S 167 
AB3 4 5 N TRP D 176 ? N TRP S 164 O LEU D 188 ? O LEU S 176 
AB3 5 6 N TYR D 190 ? N TYR S 178 O ASN D 194 ? O ASN S 182 
# 
_pdbx_entry_details.entry_id                   9K6L 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OG  R SER 25  ? ? O   R GLY 53  ? ? 2.09 
2 1 OD2 R ASP 46  ? ? OG1 R THR 282 ? ? 2.17 
3 1 OE1 R GLU 262 ? ? O4  R SA0 501 ? ? 2.18 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             CA 
_pdbx_validate_rmsd_angle.auth_asym_id_1             G 
_pdbx_validate_rmsd_angle.auth_comp_id_1             LEU 
_pdbx_validate_rmsd_angle.auth_seq_id_1              15 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             CB 
_pdbx_validate_rmsd_angle.auth_asym_id_2             G 
_pdbx_validate_rmsd_angle.auth_comp_id_2             LEU 
_pdbx_validate_rmsd_angle.auth_seq_id_2              15 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             CG 
_pdbx_validate_rmsd_angle.auth_asym_id_3             G 
_pdbx_validate_rmsd_angle.auth_comp_id_3             LEU 
_pdbx_validate_rmsd_angle.auth_seq_id_3              15 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                130.47 
_pdbx_validate_rmsd_angle.angle_target_value         115.30 
_pdbx_validate_rmsd_angle.angle_deviation            15.17 
_pdbx_validate_rmsd_angle.angle_standard_deviation   2.30 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 GLU A 43  ? ? 48.94   22.86   
2  1 SER A 44  ? ? -95.10  33.43   
3  1 ASP A 316 ? ? 68.43   -4.37   
4  1 ASP B 154 ? ? 67.41   -3.84   
5  1 THR B 196 ? ? 45.83   25.50   
6  1 CYS B 271 ? ? -79.77  -166.99 
7  1 LEU B 308 ? ? -102.44 77.27   
8  1 ASN G 24  ? ? -95.67  58.64   
9  1 SER S 133 ? ? 55.87   -134.52 
10 1 MET S 180 ? ? 67.01   -10.34  
11 1 PRO S 224 ? ? -64.79  75.53   
12 1 THR R 212 ? ? 69.54   -6.57   
13 1 ARG R 255 ? ? -64.99  5.93    
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9K6L 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9K6L 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.77 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               1064319 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'tas2r16 with gi2' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
# 
_em_imaging.entry_id                        9K6L 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TALOS ARCTICA' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9K6L 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9K6L 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1    ? A MET 1    
2   1 Y 1 A GLY 2    ? A GLY 2    
3   1 Y 1 A CYS 3    ? A CYS 3    
4   1 Y 1 A HIS 57   ? A HIS 57   
5   1 Y 1 A GLU 58   ? A GLU 58   
6   1 Y 1 A ASP 59   ? A ASP 59   
7   1 Y 1 A GLY 60   ? A GLY 60   
8   1 Y 1 A TYR 61   ? A TYR 61   
9   1 Y 1 A SER 62   ? A SER 62   
10  1 Y 1 A GLU 63   ? A GLU 63   
11  1 Y 1 A GLU 64   ? A GLU 64   
12  1 Y 1 A GLU 65   ? A GLU 65   
13  1 Y 1 A CYS 66   ? A CYS 66   
14  1 Y 1 A ARG 67   ? A ARG 67   
15  1 Y 1 A GLN 68   ? A GLN 68   
16  1 Y 1 A TYR 69   ? A TYR 69   
17  1 Y 1 A ARG 70   ? A ARG 70   
18  1 Y 1 A ALA 71   ? A ALA 71   
19  1 Y 1 A VAL 72   ? A VAL 72   
20  1 Y 1 A VAL 73   ? A VAL 73   
21  1 Y 1 A TYR 74   ? A TYR 74   
22  1 Y 1 A SER 75   ? A SER 75   
23  1 Y 1 A ASN 76   ? A ASN 76   
24  1 Y 1 A THR 77   ? A THR 77   
25  1 Y 1 A ILE 78   ? A ILE 78   
26  1 Y 1 A GLN 79   ? A GLN 79   
27  1 Y 1 A SER 80   ? A SER 80   
28  1 Y 1 A ILE 81   ? A ILE 81   
29  1 Y 1 A MET 82   ? A MET 82   
30  1 Y 1 A ALA 83   ? A ALA 83   
31  1 Y 1 A ILE 84   ? A ILE 84   
32  1 Y 1 A VAL 85   ? A VAL 85   
33  1 Y 1 A LYS 86   ? A LYS 86   
34  1 Y 1 A ALA 87   ? A ALA 87   
35  1 Y 1 A MET 88   ? A MET 88   
36  1 Y 1 A GLY 89   ? A GLY 89   
37  1 Y 1 A ASN 90   ? A ASN 90   
38  1 Y 1 A LEU 91   ? A LEU 91   
39  1 Y 1 A GLN 92   ? A GLN 92   
40  1 Y 1 A ILE 93   ? A ILE 93   
41  1 Y 1 A ASP 94   ? A ASP 94   
42  1 Y 1 A PHE 95   ? A PHE 95   
43  1 Y 1 A ALA 96   ? A ALA 96   
44  1 Y 1 A ASP 97   ? A ASP 97   
45  1 Y 1 A PRO 98   ? A PRO 98   
46  1 Y 1 A SER 99   ? A SER 99   
47  1 Y 1 A ARG 100  ? A ARG 100  
48  1 Y 1 A ALA 101  ? A ALA 101  
49  1 Y 1 A ASP 102  ? A ASP 102  
50  1 Y 1 A ASP 103  ? A ASP 103  
51  1 Y 1 A ALA 104  ? A ALA 104  
52  1 Y 1 A ARG 105  ? A ARG 105  
53  1 Y 1 A GLN 106  ? A GLN 106  
54  1 Y 1 A LEU 107  ? A LEU 107  
55  1 Y 1 A PHE 108  ? A PHE 108  
56  1 Y 1 A ALA 109  ? A ALA 109  
57  1 Y 1 A LEU 110  ? A LEU 110  
58  1 Y 1 A SER 111  ? A SER 111  
59  1 Y 1 A CYS 112  ? A CYS 112  
60  1 Y 1 A THR 113  ? A THR 113  
61  1 Y 1 A ALA 114  ? A ALA 114  
62  1 Y 1 A GLU 115  ? A GLU 115  
63  1 Y 1 A GLU 116  ? A GLU 116  
64  1 Y 1 A GLN 117  ? A GLN 117  
65  1 Y 1 A GLY 118  ? A GLY 118  
66  1 Y 1 A VAL 119  ? A VAL 119  
67  1 Y 1 A LEU 120  ? A LEU 120  
68  1 Y 1 A PRO 121  ? A PRO 121  
69  1 Y 1 A ASP 122  ? A ASP 122  
70  1 Y 1 A ASP 123  ? A ASP 123  
71  1 Y 1 A LEU 124  ? A LEU 124  
72  1 Y 1 A SER 125  ? A SER 125  
73  1 Y 1 A GLY 126  ? A GLY 126  
74  1 Y 1 A VAL 127  ? A VAL 127  
75  1 Y 1 A ILE 128  ? A ILE 128  
76  1 Y 1 A ARG 129  ? A ARG 129  
77  1 Y 1 A ARG 130  ? A ARG 130  
78  1 Y 1 A LEU 131  ? A LEU 131  
79  1 Y 1 A TRP 132  ? A TRP 132  
80  1 Y 1 A ALA 133  ? A ALA 133  
81  1 Y 1 A ASP 134  ? A ASP 134  
82  1 Y 1 A HIS 135  ? A HIS 135  
83  1 Y 1 A GLY 136  ? A GLY 136  
84  1 Y 1 A VAL 137  ? A VAL 137  
85  1 Y 1 A GLN 138  ? A GLN 138  
86  1 Y 1 A ALA 139  ? A ALA 139  
87  1 Y 1 A CYS 140  ? A CYS 140  
88  1 Y 1 A PHE 141  ? A PHE 141  
89  1 Y 1 A GLY 142  ? A GLY 142  
90  1 Y 1 A ARG 143  ? A ARG 143  
91  1 Y 1 A SER 144  ? A SER 144  
92  1 Y 1 A ARG 145  ? A ARG 145  
93  1 Y 1 A GLU 146  ? A GLU 146  
94  1 Y 1 A TYR 147  ? A TYR 147  
95  1 Y 1 A GLN 148  ? A GLN 148  
96  1 Y 1 A LEU 149  ? A LEU 149  
97  1 Y 1 A ASN 150  ? A ASN 150  
98  1 Y 1 A ASP 151  ? A ASP 151  
99  1 Y 1 A SER 152  ? A SER 152  
100 1 Y 1 A ALA 153  ? A ALA 153  
101 1 Y 1 A ALA 154  ? A ALA 154  
102 1 Y 1 A TYR 155  ? A TYR 155  
103 1 Y 1 A TYR 156  ? A TYR 156  
104 1 Y 1 A LEU 157  ? A LEU 157  
105 1 Y 1 A ASN 158  ? A ASN 158  
106 1 Y 1 A ASP 159  ? A ASP 159  
107 1 Y 1 A LEU 160  ? A LEU 160  
108 1 Y 1 A GLU 161  ? A GLU 161  
109 1 Y 1 A ARG 162  ? A ARG 162  
110 1 Y 1 A ILE 163  ? A ILE 163  
111 1 Y 1 A ALA 164  ? A ALA 164  
112 1 Y 1 A GLN 165  ? A GLN 165  
113 1 Y 1 A SER 166  ? A SER 166  
114 1 Y 1 A ASP 167  ? A ASP 167  
115 1 Y 1 A TYR 168  ? A TYR 168  
116 1 Y 1 A ILE 169  ? A ILE 169  
117 1 Y 1 A PRO 170  ? A PRO 170  
118 1 Y 1 A THR 171  ? A THR 171  
119 1 Y 1 A GLN 172  ? A GLN 172  
120 1 Y 1 A GLN 173  ? A GLN 173  
121 1 Y 1 A ASP 174  ? A ASP 174  
122 1 Y 1 A VAL 175  ? A VAL 175  
123 1 Y 1 A LEU 176  ? A LEU 176  
124 1 Y 1 A ARG 177  ? A ARG 177  
125 1 Y 1 A THR 178  ? A THR 178  
126 1 Y 1 A ARG 179  ? A ARG 179  
127 1 Y 1 A VAL 180  ? A VAL 180  
128 1 Y 1 A LYS 181  ? A LYS 181  
129 1 Y 1 A THR 182  ? A THR 182  
130 1 Y 1 B MET 1    ? B MET 1    
131 1 Y 1 B SER 2    ? B SER 2    
132 1 Y 1 B GLY 344  ? B GLY 344  
133 1 Y 1 B GLY 345  ? B GLY 345  
134 1 Y 1 B GLY 346  ? B GLY 346  
135 1 Y 1 B GLY 347  ? B GLY 347  
136 1 Y 1 B SER 348  ? B SER 348  
137 1 Y 1 B GLY 349  ? B GLY 349  
138 1 Y 1 B GLY 350  ? B GLY 350  
139 1 Y 1 B GLY 351  ? B GLY 351  
140 1 Y 1 B GLY 352  ? B GLY 352  
141 1 Y 1 B SER 353  ? B SER 353  
142 1 Y 1 B SER 354  ? B SER 354  
143 1 Y 1 B GLY 355  ? B GLY 355  
144 1 Y 1 B VAL 356  ? B VAL 356  
145 1 Y 1 B SER 357  ? B SER 357  
146 1 Y 1 B GLY 358  ? B GLY 358  
147 1 Y 1 B TRP 359  ? B TRP 359  
148 1 Y 1 B ARG 360  ? B ARG 360  
149 1 Y 1 B LEU 361  ? B LEU 361  
150 1 Y 1 B PHE 362  ? B PHE 362  
151 1 Y 1 B LYS 363  ? B LYS 363  
152 1 Y 1 B LYS 364  ? B LYS 364  
153 1 Y 1 B ILE 365  ? B ILE 365  
154 1 Y 1 B SER 366  ? B SER 366  
155 1 Y 1 G MET 1    ? C MET 1    
156 1 Y 1 G ALA 2    ? C ALA 2    
157 1 Y 1 G SER 3    ? C SER 3    
158 1 Y 1 G ASN 4    ? C ASN 4    
159 1 Y 1 G ASN 5    ? C ASN 5    
160 1 Y 1 G GLU 63   ? C GLU 63   
161 1 Y 1 G LYS 64   ? C LYS 64   
162 1 Y 1 G LYS 65   ? C LYS 65   
163 1 Y 1 G PHE 66   ? C PHE 66   
164 1 Y 1 G PHE 67   ? C PHE 67   
165 1 Y 1 G CYS 68   ? C CYS 68   
166 1 Y 1 G ALA 69   ? C ALA 69   
167 1 Y 1 G ILE 70   ? C ILE 70   
168 1 Y 1 G LEU 71   ? C LEU 71   
169 1 Y 1 S ASP 1    ? D ASP 1    
170 1 Y 1 S GLY 121  A D GLY 122  
171 1 Y 1 S GLY 121  B D GLY 123  
172 1 Y 1 S GLY 121  C D GLY 124  
173 1 Y 1 S GLY 121  D D GLY 125  
174 1 Y 1 S SER 121  E D SER 126  
175 1 Y 1 S GLY 121  F D GLY 127  
176 1 Y 1 S GLY 121  G D GLY 128  
177 1 Y 1 S GLY 121  H D GLY 129  
178 1 Y 1 S GLY 121  I D GLY 130  
179 1 Y 1 S SER 121  J D SER 131  
180 1 Y 1 S GLY 121  K D GLY 132  
181 1 Y 1 S GLY 121  L D GLY 133  
182 1 Y 1 S GLY 121  M D GLY 134  
183 1 Y 1 S GLY 121  N D GLY 135  
184 1 Y 1 S LYS 236  ? D LYS 248  
185 1 Y 1 S ALA 237  ? D ALA 249  
186 1 Y 1 S ALA 238  ? D ALA 250  
187 1 Y 1 S ALA 239  ? D ALA 251  
188 1 Y 1 S GLU 240  ? D GLU 252  
189 1 Y 1 S ASN 241  ? D ASN 253  
190 1 Y 1 S LEU 242  ? D LEU 254  
191 1 Y 1 S TYR 243  ? D TYR 255  
192 1 Y 1 S PHE 244  ? D PHE 256  
193 1 Y 1 S GLN 245  ? D GLN 257  
194 1 Y 1 S SER 246  ? D SER 258  
195 1 Y 1 S HIS 247  ? D HIS 259  
196 1 Y 1 S HIS 248  ? D HIS 260  
197 1 Y 1 S HIS 249  ? D HIS 261  
198 1 Y 1 S HIS 250  ? D HIS 262  
199 1 Y 1 S HIS 251  ? D HIS 263  
200 1 Y 1 S HIS 252  ? D HIS 264  
201 1 Y 1 S HIS 253  ? D HIS 265  
202 1 Y 1 S HIS 254  ? D HIS 266  
203 1 Y 1 R MET -537 ? E MET 1    
204 1 Y 1 R LYS -536 ? E LYS 2    
205 1 Y 1 R THR -535 ? E THR 3    
206 1 Y 1 R ILE -534 ? E ILE 4    
207 1 Y 1 R ILE -533 ? E ILE 5    
208 1 Y 1 R ALA -532 ? E ALA 6    
209 1 Y 1 R LEU -531 ? E LEU 7    
210 1 Y 1 R SER -530 ? E SER 8    
211 1 Y 1 R TYR -529 ? E TYR 9    
212 1 Y 1 R ILE -528 ? E ILE 10   
213 1 Y 1 R PHE -527 ? E PHE 11   
214 1 Y 1 R CYS -526 ? E CYS 12   
215 1 Y 1 R LEU -525 ? E LEU 13   
216 1 Y 1 R VAL -524 ? E VAL 14   
217 1 Y 1 R PHE -523 ? E PHE 15   
218 1 Y 1 R ALA -522 ? E ALA 16   
219 1 Y 1 R ASP -521 ? E ASP 17   
220 1 Y 1 R TYR -520 ? E TYR 18   
221 1 Y 1 R LYS -519 ? E LYS 19   
222 1 Y 1 R ASP -518 ? E ASP 20   
223 1 Y 1 R ASP -517 ? E ASP 21   
224 1 Y 1 R ASP -516 ? E ASP 22   
225 1 Y 1 R ASP -515 ? E ASP 23   
226 1 Y 1 R ALA -514 ? E ALA 24   
227 1 Y 1 R HIS -513 ? E HIS 25   
228 1 Y 1 R HIS -512 ? E HIS 26   
229 1 Y 1 R HIS -511 ? E HIS 27   
230 1 Y 1 R HIS -510 ? E HIS 28   
231 1 Y 1 R HIS -509 ? E HIS 29   
232 1 Y 1 R HIS -508 ? E HIS 30   
233 1 Y 1 R HIS -507 ? E HIS 31   
234 1 Y 1 R HIS -506 ? E HIS 32   
235 1 Y 1 R HIS -505 ? E HIS 33   
236 1 Y 1 R HIS -504 ? E HIS 34   
237 1 Y 1 R GLU -503 ? E GLU 35   
238 1 Y 1 R ASN -502 ? E ASN 36   
239 1 Y 1 R LEU -501 ? E LEU 37   
240 1 Y 1 R TYR -500 ? E TYR 38   
241 1 Y 1 R PHE -499 ? E PHE 39   
242 1 Y 1 R GLN -498 ? E GLN 40   
243 1 Y 1 R SER -497 ? E SER 41   
244 1 Y 1 R ALA -496 ? E ALA 42   
245 1 Y 1 R HIS -495 ? E HIS 43   
246 1 Y 1 R HIS -494 ? E HIS 44   
247 1 Y 1 R HIS -493 ? E HIS 45   
248 1 Y 1 R HIS -492 ? E HIS 46   
249 1 Y 1 R HIS -491 ? E HIS 47   
250 1 Y 1 R HIS -490 ? E HIS 48   
251 1 Y 1 R SER -489 ? E SER 49   
252 1 Y 1 R SER -488 ? E SER 50   
253 1 Y 1 R GLY -487 ? E GLY 51   
254 1 Y 1 R LEU -486 ? E LEU 52   
255 1 Y 1 R GLU -485 ? E GLU 53   
256 1 Y 1 R VAL -484 ? E VAL 54   
257 1 Y 1 R LEU -483 ? E LEU 55   
258 1 Y 1 R PHE -482 ? E PHE 56   
259 1 Y 1 R GLN -481 ? E GLN 57   
260 1 Y 1 R GLY -480 ? E GLY 58   
261 1 Y 1 R PRO -479 ? E PRO 59   
262 1 Y 1 R PRO -478 ? E PRO 60   
263 1 Y 1 R GLU -477 ? E GLU 61   
264 1 Y 1 R GLY -476 ? E GLY 62   
265 1 Y 1 R ALA -475 ? E ALA 63   
266 1 Y 1 R ALA -474 ? E ALA 64   
267 1 Y 1 R LEU -473 ? E LEU 65   
268 1 Y 1 R THR -472 ? E THR 66   
269 1 Y 1 R GLU -471 ? E GLU 67   
270 1 Y 1 R LYS -470 ? E LYS 68   
271 1 Y 1 R THR -469 ? E THR 69   
272 1 Y 1 R ASP -468 ? E ASP 70   
273 1 Y 1 R ILE -467 ? E ILE 71   
274 1 Y 1 R PHE -466 ? E PHE 72   
275 1 Y 1 R GLU -465 ? E GLU 73   
276 1 Y 1 R SER -464 ? E SER 74   
277 1 Y 1 R GLY -463 ? E GLY 75   
278 1 Y 1 R ARG -462 ? E ARG 76   
279 1 Y 1 R ASN -461 ? E ASN 77   
280 1 Y 1 R GLY -460 ? E GLY 78   
281 1 Y 1 R ASN -459 ? E ASN 79   
282 1 Y 1 R PRO -458 ? E PRO 80   
283 1 Y 1 R ASN -457 ? E ASN 81   
284 1 Y 1 R LYS -456 ? E LYS 82   
285 1 Y 1 R ASP -455 ? E ASP 83   
286 1 Y 1 R GLY -454 ? E GLY 84   
287 1 Y 1 R ILE -453 ? E ILE 85   
288 1 Y 1 R LYS -452 ? E LYS 86   
289 1 Y 1 R SER -451 ? E SER 87   
290 1 Y 1 R TYR -450 ? E TYR 88   
291 1 Y 1 R ARG -449 ? E ARG 89   
292 1 Y 1 R ILE -448 ? E ILE 90   
293 1 Y 1 R PRO -447 ? E PRO 91   
294 1 Y 1 R ALA -446 ? E ALA 92   
295 1 Y 1 R LEU -445 ? E LEU 93   
296 1 Y 1 R LEU -444 ? E LEU 94   
297 1 Y 1 R LYS -443 ? E LYS 95   
298 1 Y 1 R THR -442 ? E THR 96   
299 1 Y 1 R ASP -441 ? E ASP 97   
300 1 Y 1 R LYS -440 ? E LYS 98   
301 1 Y 1 R GLY -439 ? E GLY 99   
302 1 Y 1 R THR -438 ? E THR 100  
303 1 Y 1 R LEU -437 ? E LEU 101  
304 1 Y 1 R ILE -436 ? E ILE 102  
305 1 Y 1 R ALA -435 ? E ALA 103  
306 1 Y 1 R GLY -434 ? E GLY 104  
307 1 Y 1 R ALA -433 ? E ALA 105  
308 1 Y 1 R ASP -432 ? E ASP 106  
309 1 Y 1 R GLU -431 ? E GLU 107  
310 1 Y 1 R ARG -430 ? E ARG 108  
311 1 Y 1 R ARG -429 ? E ARG 109  
312 1 Y 1 R LEU -428 ? E LEU 110  
313 1 Y 1 R HIS -427 ? E HIS 111  
314 1 Y 1 R SER -426 ? E SER 112  
315 1 Y 1 R SER -425 ? E SER 113  
316 1 Y 1 R ASP -424 ? E ASP 114  
317 1 Y 1 R TRP -423 ? E TRP 115  
318 1 Y 1 R GLY -422 ? E GLY 116  
319 1 Y 1 R ASP -421 ? E ASP 117  
320 1 Y 1 R ILE -420 ? E ILE 118  
321 1 Y 1 R GLY -419 ? E GLY 119  
322 1 Y 1 R MET -418 ? E MET 120  
323 1 Y 1 R VAL -417 ? E VAL 121  
324 1 Y 1 R ILE -416 ? E ILE 122  
325 1 Y 1 R ARG -415 ? E ARG 123  
326 1 Y 1 R ARG -414 ? E ARG 124  
327 1 Y 1 R SER -413 ? E SER 125  
328 1 Y 1 R GLU -412 ? E GLU 126  
329 1 Y 1 R ASP -411 ? E ASP 127  
330 1 Y 1 R ASN -410 ? E ASN 128  
331 1 Y 1 R GLY -409 ? E GLY 129  
332 1 Y 1 R LYS -408 ? E LYS 130  
333 1 Y 1 R THR -407 ? E THR 131  
334 1 Y 1 R TRP -406 ? E TRP 132  
335 1 Y 1 R GLY -405 ? E GLY 133  
336 1 Y 1 R ASP -404 ? E ASP 134  
337 1 Y 1 R ARG -403 ? E ARG 135  
338 1 Y 1 R VAL -402 ? E VAL 136  
339 1 Y 1 R THR -401 ? E THR 137  
340 1 Y 1 R ILE -400 ? E ILE 138  
341 1 Y 1 R THR -399 ? E THR 139  
342 1 Y 1 R ASN -398 ? E ASN 140  
343 1 Y 1 R LEU -397 ? E LEU 141  
344 1 Y 1 R ARG -396 ? E ARG 142  
345 1 Y 1 R ASP -395 ? E ASP 143  
346 1 Y 1 R ASN -394 ? E ASN 144  
347 1 Y 1 R PRO -393 ? E PRO 145  
348 1 Y 1 R LYS -392 ? E LYS 146  
349 1 Y 1 R ALA -391 ? E ALA 147  
350 1 Y 1 R SER -390 ? E SER 148  
351 1 Y 1 R ASP -389 ? E ASP 149  
352 1 Y 1 R PRO -388 ? E PRO 150  
353 1 Y 1 R SER -387 ? E SER 151  
354 1 Y 1 R ILE -386 ? E ILE 152  
355 1 Y 1 R GLY -385 ? E GLY 153  
356 1 Y 1 R SER -384 ? E SER 154  
357 1 Y 1 R PRO -383 ? E PRO 155  
358 1 Y 1 R VAL -382 ? E VAL 156  
359 1 Y 1 R ASN -381 ? E ASN 157  
360 1 Y 1 R ILE -380 ? E ILE 158  
361 1 Y 1 R ASP -379 ? E ASP 159  
362 1 Y 1 R MET -378 ? E MET 160  
363 1 Y 1 R VAL -377 ? E VAL 161  
364 1 Y 1 R LEU -376 ? E LEU 162  
365 1 Y 1 R VAL -375 ? E VAL 163  
366 1 Y 1 R GLN -374 ? E GLN 164  
367 1 Y 1 R ASP -373 ? E ASP 165  
368 1 Y 1 R PRO -372 ? E PRO 166  
369 1 Y 1 R GLU -371 ? E GLU 167  
370 1 Y 1 R THR -370 ? E THR 168  
371 1 Y 1 R LYS -369 ? E LYS 169  
372 1 Y 1 R ARG -368 ? E ARG 170  
373 1 Y 1 R ILE -367 ? E ILE 171  
374 1 Y 1 R PHE -366 ? E PHE 172  
375 1 Y 1 R SER -365 ? E SER 173  
376 1 Y 1 R ILE -364 ? E ILE 174  
377 1 Y 1 R TYR -363 ? E TYR 175  
378 1 Y 1 R ASP -362 ? E ASP 176  
379 1 Y 1 R MET -361 ? E MET 177  
380 1 Y 1 R PHE -360 ? E PHE 178  
381 1 Y 1 R PRO -359 ? E PRO 179  
382 1 Y 1 R GLU -358 ? E GLU 180  
383 1 Y 1 R GLY -357 ? E GLY 181  
384 1 Y 1 R LYS -356 ? E LYS 182  
385 1 Y 1 R GLY -355 ? E GLY 183  
386 1 Y 1 R ILE -354 ? E ILE 184  
387 1 Y 1 R PHE -353 ? E PHE 185  
388 1 Y 1 R GLY -352 ? E GLY 186  
389 1 Y 1 R MET -351 ? E MET 187  
390 1 Y 1 R SER -350 ? E SER 188  
391 1 Y 1 R SER -349 ? E SER 189  
392 1 Y 1 R GLN -348 ? E GLN 190  
393 1 Y 1 R LYS -347 ? E LYS 191  
394 1 Y 1 R GLU -346 ? E GLU 192  
395 1 Y 1 R GLU -345 ? E GLU 193  
396 1 Y 1 R ALA -344 ? E ALA 194  
397 1 Y 1 R TYR -343 ? E TYR 195  
398 1 Y 1 R LYS -342 ? E LYS 196  
399 1 Y 1 R LYS -341 ? E LYS 197  
400 1 Y 1 R ILE -340 ? E ILE 198  
401 1 Y 1 R ASP -339 ? E ASP 199  
402 1 Y 1 R GLY -338 ? E GLY 200  
403 1 Y 1 R LYS -337 ? E LYS 201  
404 1 Y 1 R THR -336 ? E THR 202  
405 1 Y 1 R TYR -335 ? E TYR 203  
406 1 Y 1 R GLN -334 ? E GLN 204  
407 1 Y 1 R ILE -333 ? E ILE 205  
408 1 Y 1 R LEU -332 ? E LEU 206  
409 1 Y 1 R TYR -331 ? E TYR 207  
410 1 Y 1 R ARG -330 ? E ARG 208  
411 1 Y 1 R GLU -329 ? E GLU 209  
412 1 Y 1 R GLY -328 ? E GLY 210  
413 1 Y 1 R GLU -327 ? E GLU 211  
414 1 Y 1 R LYS -326 ? E LYS 212  
415 1 Y 1 R GLY -325 ? E GLY 213  
416 1 Y 1 R ALA -324 ? E ALA 214  
417 1 Y 1 R TYR -323 ? E TYR 215  
418 1 Y 1 R THR -322 ? E THR 216  
419 1 Y 1 R ILE -321 ? E ILE 217  
420 1 Y 1 R ARG -320 ? E ARG 218  
421 1 Y 1 R GLU -319 ? E GLU 219  
422 1 Y 1 R ASN -318 ? E ASN 220  
423 1 Y 1 R GLY -317 ? E GLY 221  
424 1 Y 1 R THR -316 ? E THR 222  
425 1 Y 1 R VAL -315 ? E VAL 223  
426 1 Y 1 R TYR -314 ? E TYR 224  
427 1 Y 1 R THR -313 ? E THR 225  
428 1 Y 1 R PRO -312 ? E PRO 226  
429 1 Y 1 R ASP -311 ? E ASP 227  
430 1 Y 1 R GLY -310 ? E GLY 228  
431 1 Y 1 R LYS -309 ? E LYS 229  
432 1 Y 1 R ALA -308 ? E ALA 230  
433 1 Y 1 R THR -307 ? E THR 231  
434 1 Y 1 R ASP -306 ? E ASP 232  
435 1 Y 1 R TYR -305 ? E TYR 233  
436 1 Y 1 R ARG -304 ? E ARG 234  
437 1 Y 1 R VAL -303 ? E VAL 235  
438 1 Y 1 R VAL -302 ? E VAL 236  
439 1 Y 1 R VAL -301 ? E VAL 237  
440 1 Y 1 R ASP -300 ? E ASP 238  
441 1 Y 1 R PRO -299 ? E PRO 239  
442 1 Y 1 R VAL -298 ? E VAL 240  
443 1 Y 1 R LYS -297 ? E LYS 241  
444 1 Y 1 R PRO -296 ? E PRO 242  
445 1 Y 1 R ALA -295 ? E ALA 243  
446 1 Y 1 R TYR -294 ? E TYR 244  
447 1 Y 1 R SER -293 ? E SER 245  
448 1 Y 1 R ASP -292 ? E ASP 246  
449 1 Y 1 R LYS -291 ? E LYS 247  
450 1 Y 1 R GLY -290 ? E GLY 248  
451 1 Y 1 R ASP -289 ? E ASP 249  
452 1 Y 1 R LEU -288 ? E LEU 250  
453 1 Y 1 R TYR -287 ? E TYR 251  
454 1 Y 1 R LYS -286 ? E LYS 252  
455 1 Y 1 R GLY -285 ? E GLY 253  
456 1 Y 1 R ASP -284 ? E ASP 254  
457 1 Y 1 R GLN -283 ? E GLN 255  
458 1 Y 1 R LEU -282 ? E LEU 256  
459 1 Y 1 R LEU -281 ? E LEU 257  
460 1 Y 1 R GLY -280 ? E GLY 258  
461 1 Y 1 R ASN -279 ? E ASN 259  
462 1 Y 1 R ILE -278 ? E ILE 260  
463 1 Y 1 R TYR -277 ? E TYR 261  
464 1 Y 1 R PHE -276 ? E PHE 262  
465 1 Y 1 R THR -275 ? E THR 263  
466 1 Y 1 R THR -274 ? E THR 264  
467 1 Y 1 R ASN -273 ? E ASN 265  
468 1 Y 1 R LYS -272 ? E LYS 266  
469 1 Y 1 R THR -271 ? E THR 267  
470 1 Y 1 R SER -270 ? E SER 268  
471 1 Y 1 R PRO -269 ? E PRO 269  
472 1 Y 1 R PHE -268 ? E PHE 270  
473 1 Y 1 R ARG -267 ? E ARG 271  
474 1 Y 1 R ILE -266 ? E ILE 272  
475 1 Y 1 R ALA -265 ? E ALA 273  
476 1 Y 1 R LYS -264 ? E LYS 274  
477 1 Y 1 R ASP -263 ? E ASP 275  
478 1 Y 1 R SER -262 ? E SER 276  
479 1 Y 1 R TYR -261 ? E TYR 277  
480 1 Y 1 R LEU -260 ? E LEU 278  
481 1 Y 1 R TRP -259 ? E TRP 279  
482 1 Y 1 R MET -258 ? E MET 280  
483 1 Y 1 R SER -257 ? E SER 281  
484 1 Y 1 R TYR -256 ? E TYR 282  
485 1 Y 1 R SER -255 ? E SER 283  
486 1 Y 1 R ASP -254 ? E ASP 284  
487 1 Y 1 R ASP -253 ? E ASP 285  
488 1 Y 1 R ASP -252 ? E ASP 286  
489 1 Y 1 R GLY -251 ? E GLY 287  
490 1 Y 1 R LYS -250 ? E LYS 288  
491 1 Y 1 R THR -249 ? E THR 289  
492 1 Y 1 R TRP -248 ? E TRP 290  
493 1 Y 1 R SER -247 ? E SER 291  
494 1 Y 1 R ALA -246 ? E ALA 292  
495 1 Y 1 R PRO -245 ? E PRO 293  
496 1 Y 1 R GLN -244 ? E GLN 294  
497 1 Y 1 R ASP -243 ? E ASP 295  
498 1 Y 1 R ILE -242 ? E ILE 296  
499 1 Y 1 R THR -241 ? E THR 297  
500 1 Y 1 R PRO -240 ? E PRO 298  
501 1 Y 1 R MET -239 ? E MET 299  
502 1 Y 1 R VAL -238 ? E VAL 300  
503 1 Y 1 R LYS -237 ? E LYS 301  
504 1 Y 1 R ALA -236 ? E ALA 302  
505 1 Y 1 R ASP -235 ? E ASP 303  
506 1 Y 1 R TRP -234 ? E TRP 304  
507 1 Y 1 R MET -233 ? E MET 305  
508 1 Y 1 R LYS -232 ? E LYS 306  
509 1 Y 1 R PHE -231 ? E PHE 307  
510 1 Y 1 R LEU -230 ? E LEU 308  
511 1 Y 1 R GLY -229 ? E GLY 309  
512 1 Y 1 R VAL -228 ? E VAL 310  
513 1 Y 1 R GLY -227 ? E GLY 311  
514 1 Y 1 R PRO -226 ? E PRO 312  
515 1 Y 1 R GLY -225 ? E GLY 313  
516 1 Y 1 R THR -224 ? E THR 314  
517 1 Y 1 R GLY -223 ? E GLY 315  
518 1 Y 1 R ILE -222 ? E ILE 316  
519 1 Y 1 R VAL -221 ? E VAL 317  
520 1 Y 1 R LEU -220 ? E LEU 318  
521 1 Y 1 R ARG -219 ? E ARG 319  
522 1 Y 1 R ASN -218 ? E ASN 320  
523 1 Y 1 R GLY -217 ? E GLY 321  
524 1 Y 1 R PRO -216 ? E PRO 322  
525 1 Y 1 R HIS -215 ? E HIS 323  
526 1 Y 1 R LYS -214 ? E LYS 324  
527 1 Y 1 R GLY -213 ? E GLY 325  
528 1 Y 1 R ARG -212 ? E ARG 326  
529 1 Y 1 R ILE -211 ? E ILE 327  
530 1 Y 1 R LEU -210 ? E LEU 328  
531 1 Y 1 R ILE -209 ? E ILE 329  
532 1 Y 1 R PRO -208 ? E PRO 330  
533 1 Y 1 R VAL -207 ? E VAL 331  
534 1 Y 1 R TYR -206 ? E TYR 332  
535 1 Y 1 R THR -205 ? E THR 333  
536 1 Y 1 R THR -204 ? E THR 334  
537 1 Y 1 R ASN -203 ? E ASN 335  
538 1 Y 1 R ASN -202 ? E ASN 336  
539 1 Y 1 R VAL -201 ? E VAL 337  
540 1 Y 1 R SER -200 ? E SER 338  
541 1 Y 1 R HIS -199 ? E HIS 339  
542 1 Y 1 R LEU -198 ? E LEU 340  
543 1 Y 1 R ASP -197 ? E ASP 341  
544 1 Y 1 R GLY -196 ? E GLY 342  
545 1 Y 1 R SER -195 ? E SER 343  
546 1 Y 1 R GLN -194 ? E GLN 344  
547 1 Y 1 R SER -193 ? E SER 345  
548 1 Y 1 R SER -192 ? E SER 346  
549 1 Y 1 R ARG -191 ? E ARG 347  
550 1 Y 1 R VAL -190 ? E VAL 348  
551 1 Y 1 R ILE -189 ? E ILE 349  
552 1 Y 1 R TYR -188 ? E TYR 350  
553 1 Y 1 R SER -187 ? E SER 351  
554 1 Y 1 R ASP -186 ? E ASP 352  
555 1 Y 1 R ASP -185 ? E ASP 353  
556 1 Y 1 R HIS -184 ? E HIS 354  
557 1 Y 1 R GLY -183 ? E GLY 355  
558 1 Y 1 R LYS -182 ? E LYS 356  
559 1 Y 1 R THR -181 ? E THR 357  
560 1 Y 1 R TRP -180 ? E TRP 358  
561 1 Y 1 R HIS -179 ? E HIS 359  
562 1 Y 1 R ALA -178 ? E ALA 360  
563 1 Y 1 R GLY -177 ? E GLY 361  
564 1 Y 1 R GLU -176 ? E GLU 362  
565 1 Y 1 R ALA -175 ? E ALA 363  
566 1 Y 1 R VAL -174 ? E VAL 364  
567 1 Y 1 R ASN -173 ? E ASN 365  
568 1 Y 1 R ASP -172 ? E ASP 366  
569 1 Y 1 R ASN -171 ? E ASN 367  
570 1 Y 1 R ARG -170 ? E ARG 368  
571 1 Y 1 R GLN -169 ? E GLN 369  
572 1 Y 1 R VAL -168 ? E VAL 370  
573 1 Y 1 R ASP -167 ? E ASP 371  
574 1 Y 1 R GLY -166 ? E GLY 372  
575 1 Y 1 R GLN -165 ? E GLN 373  
576 1 Y 1 R LYS -164 ? E LYS 374  
577 1 Y 1 R ILE -163 ? E ILE 375  
578 1 Y 1 R HIS -162 ? E HIS 376  
579 1 Y 1 R SER -161 ? E SER 377  
580 1 Y 1 R SER -160 ? E SER 378  
581 1 Y 1 R THR -159 ? E THR 379  
582 1 Y 1 R MET -158 ? E MET 380  
583 1 Y 1 R ASN -157 ? E ASN 381  
584 1 Y 1 R ASN -156 ? E ASN 382  
585 1 Y 1 R ARG -155 ? E ARG 383  
586 1 Y 1 R ARG -154 ? E ARG 384  
587 1 Y 1 R ALA -153 ? E ALA 385  
588 1 Y 1 R GLN -152 ? E GLN 386  
589 1 Y 1 R ASN -151 ? E ASN 387  
590 1 Y 1 R THR -150 ? E THR 388  
591 1 Y 1 R GLU -149 ? E GLU 389  
592 1 Y 1 R SER -148 ? E SER 390  
593 1 Y 1 R THR -147 ? E THR 391  
594 1 Y 1 R VAL -146 ? E VAL 392  
595 1 Y 1 R VAL -145 ? E VAL 393  
596 1 Y 1 R GLN -144 ? E GLN 394  
597 1 Y 1 R LEU -143 ? E LEU 395  
598 1 Y 1 R ASN -142 ? E ASN 396  
599 1 Y 1 R ASN -141 ? E ASN 397  
600 1 Y 1 R GLY -140 ? E GLY 398  
601 1 Y 1 R ASP -139 ? E ASP 399  
602 1 Y 1 R VAL -138 ? E VAL 400  
603 1 Y 1 R LYS -137 ? E LYS 401  
604 1 Y 1 R LEU -136 ? E LEU 402  
605 1 Y 1 R PHE -135 ? E PHE 403  
606 1 Y 1 R MET -134 ? E MET 404  
607 1 Y 1 R ARG -133 ? E ARG 405  
608 1 Y 1 R GLY -132 ? E GLY 406  
609 1 Y 1 R LEU -131 ? E LEU 407  
610 1 Y 1 R THR -130 ? E THR 408  
611 1 Y 1 R GLY -129 ? E GLY 409  
612 1 Y 1 R ASP -128 ? E ASP 410  
613 1 Y 1 R LEU -127 ? E LEU 411  
614 1 Y 1 R GLN -126 ? E GLN 412  
615 1 Y 1 R VAL -125 ? E VAL 413  
616 1 Y 1 R ALA -124 ? E ALA 414  
617 1 Y 1 R THR -123 ? E THR 415  
618 1 Y 1 R SER -122 ? E SER 416  
619 1 Y 1 R LYS -121 ? E LYS 417  
620 1 Y 1 R ASP -120 ? E ASP 418  
621 1 Y 1 R GLY -119 ? E GLY 419  
622 1 Y 1 R GLY -118 ? E GLY 420  
623 1 Y 1 R VAL -117 ? E VAL 421  
624 1 Y 1 R THR -116 ? E THR 422  
625 1 Y 1 R TRP -115 ? E TRP 423  
626 1 Y 1 R GLU -114 ? E GLU 424  
627 1 Y 1 R LYS -113 ? E LYS 425  
628 1 Y 1 R ASP -112 ? E ASP 426  
629 1 Y 1 R ILE -111 ? E ILE 427  
630 1 Y 1 R LYS -110 ? E LYS 428  
631 1 Y 1 R ARG -109 ? E ARG 429  
632 1 Y 1 R TYR -108 ? E TYR 430  
633 1 Y 1 R PRO -107 ? E PRO 431  
634 1 Y 1 R GLN -106 ? E GLN 432  
635 1 Y 1 R VAL -105 ? E VAL 433  
636 1 Y 1 R LYS -104 ? E LYS 434  
637 1 Y 1 R ASP -103 ? E ASP 435  
638 1 Y 1 R VAL -102 ? E VAL 436  
639 1 Y 1 R TYR -101 ? E TYR 437  
640 1 Y 1 R VAL -100 ? E VAL 438  
641 1 Y 1 R GLN -99  ? E GLN 439  
642 1 Y 1 R MET -98  ? E MET 440  
643 1 Y 1 R SER -97  ? E SER 441  
644 1 Y 1 R ALA -96  ? E ALA 442  
645 1 Y 1 R ILE -95  ? E ILE 443  
646 1 Y 1 R HIS -94  ? E HIS 444  
647 1 Y 1 R THR -93  ? E THR 445  
648 1 Y 1 R MET -92  ? E MET 446  
649 1 Y 1 R HIS -91  ? E HIS 447  
650 1 Y 1 R GLU -90  ? E GLU 448  
651 1 Y 1 R GLY -89  ? E GLY 449  
652 1 Y 1 R LYS -88  ? E LYS 450  
653 1 Y 1 R GLU -87  ? E GLU 451  
654 1 Y 1 R TYR -86  ? E TYR 452  
655 1 Y 1 R ILE -85  ? E ILE 453  
656 1 Y 1 R ILE -84  ? E ILE 454  
657 1 Y 1 R LEU -83  ? E LEU 455  
658 1 Y 1 R SER -82  ? E SER 456  
659 1 Y 1 R ASN -81  ? E ASN 457  
660 1 Y 1 R ALA -80  ? E ALA 458  
661 1 Y 1 R GLY -79  ? E GLY 459  
662 1 Y 1 R GLY -78  ? E GLY 460  
663 1 Y 1 R PRO -77  ? E PRO 461  
664 1 Y 1 R LYS -76  ? E LYS 462  
665 1 Y 1 R ARG -75  ? E ARG 463  
666 1 Y 1 R GLU -74  ? E GLU 464  
667 1 Y 1 R ASN -73  ? E ASN 465  
668 1 Y 1 R GLY -72  ? E GLY 466  
669 1 Y 1 R MET -71  ? E MET 467  
670 1 Y 1 R VAL -70  ? E VAL 468  
671 1 Y 1 R HIS -69  ? E HIS 469  
672 1 Y 1 R LEU -68  ? E LEU 470  
673 1 Y 1 R ALA -67  ? E ALA 471  
674 1 Y 1 R ARG -66  ? E ARG 472  
675 1 Y 1 R VAL -65  ? E VAL 473  
676 1 Y 1 R GLU -64  ? E GLU 474  
677 1 Y 1 R GLU -63  ? E GLU 475  
678 1 Y 1 R ASN -62  ? E ASN 476  
679 1 Y 1 R GLY -61  ? E GLY 477  
680 1 Y 1 R GLU -60  ? E GLU 478  
681 1 Y 1 R LEU -59  ? E LEU 479  
682 1 Y 1 R THR -58  ? E THR 480  
683 1 Y 1 R TRP -57  ? E TRP 481  
684 1 Y 1 R LEU -56  ? E LEU 482  
685 1 Y 1 R LYS -55  ? E LYS 483  
686 1 Y 1 R HIS -54  ? E HIS 484  
687 1 Y 1 R ASN -53  ? E ASN 485  
688 1 Y 1 R PRO -52  ? E PRO 486  
689 1 Y 1 R ILE -51  ? E ILE 487  
690 1 Y 1 R GLN -50  ? E GLN 488  
691 1 Y 1 R LYS -49  ? E LYS 489  
692 1 Y 1 R GLY -48  ? E GLY 490  
693 1 Y 1 R GLU -47  ? E GLU 491  
694 1 Y 1 R PHE -46  ? E PHE 492  
695 1 Y 1 R ALA -45  ? E ALA 493  
696 1 Y 1 R TYR -44  ? E TYR 494  
697 1 Y 1 R ASN -43  ? E ASN 495  
698 1 Y 1 R SER -42  ? E SER 496  
699 1 Y 1 R LEU -41  ? E LEU 497  
700 1 Y 1 R GLN -40  ? E GLN 498  
701 1 Y 1 R GLU -39  ? E GLU 499  
702 1 Y 1 R LEU -38  ? E LEU 500  
703 1 Y 1 R GLY -37  ? E GLY 501  
704 1 Y 1 R ASN -36  ? E ASN 502  
705 1 Y 1 R GLY -35  ? E GLY 503  
706 1 Y 1 R GLU -34  ? E GLU 504  
707 1 Y 1 R TYR -33  ? E TYR 505  
708 1 Y 1 R GLY -32  ? E GLY 506  
709 1 Y 1 R ILE -31  ? E ILE 507  
710 1 Y 1 R LEU -30  ? E LEU 508  
711 1 Y 1 R TYR -29  ? E TYR 509  
712 1 Y 1 R GLU -28  ? E GLU 510  
713 1 Y 1 R HIS -27  ? E HIS 511  
714 1 Y 1 R THR -26  ? E THR 512  
715 1 Y 1 R GLU -25  ? E GLU 513  
716 1 Y 1 R LYS -24  ? E LYS 514  
717 1 Y 1 R GLY -23  ? E GLY 515  
718 1 Y 1 R GLN -22  ? E GLN 516  
719 1 Y 1 R ASN -21  ? E ASN 517  
720 1 Y 1 R ALA -20  ? E ALA 518  
721 1 Y 1 R TYR -19  ? E TYR 519  
722 1 Y 1 R THR -18  ? E THR 520  
723 1 Y 1 R LEU -17  ? E LEU 521  
724 1 Y 1 R SER -16  ? E SER 522  
725 1 Y 1 R PHE -15  ? E PHE 523  
726 1 Y 1 R ARG -14  ? E ARG 524  
727 1 Y 1 R LYS -13  ? E LYS 525  
728 1 Y 1 R PHE -12  ? E PHE 526  
729 1 Y 1 R ASN -11  ? E ASN 527  
730 1 Y 1 R TRP -10  ? E TRP 528  
731 1 Y 1 R GLU -9   ? E GLU 529  
732 1 Y 1 R PHE -8   ? E PHE 530  
733 1 Y 1 R LEU -7   ? E LEU 531  
734 1 Y 1 R SER -6   ? E SER 532  
735 1 Y 1 R LYS -5   ? E LYS 533  
736 1 Y 1 R ASN -4   ? E ASN 534  
737 1 Y 1 R GLY -3   ? E GLY 535  
738 1 Y 1 R SER -2   ? E SER 536  
739 1 Y 1 R GLY -1   ? E GLY 537  
740 1 Y 1 R SER 0    ? E SER 538  
741 1 Y 1 R GLY 1    ? E GLY 539  
742 1 Y 1 R THR 156  ? E THR 694  
743 1 Y 1 R MET 157  ? E MET 695  
744 1 Y 1 R GLU 158  ? E GLU 696  
745 1 Y 1 R HIS 159  ? E HIS 697  
746 1 Y 1 R LEU 160  ? E LEU 698  
747 1 Y 1 R PRO 161  ? E PRO 699  
748 1 Y 1 R ARG 162  ? E ARG 700  
749 1 Y 1 R ASN 163  ? E ASN 701  
750 1 Y 1 R SER 164  ? E SER 702  
751 1 Y 1 R THR 165  ? E THR 703  
752 1 Y 1 R VAL 166  ? E VAL 704  
753 1 Y 1 R THR 167  ? E THR 705  
754 1 Y 1 R ASP 168  ? E ASP 706  
755 1 Y 1 R LYS 169  ? E LYS 707  
756 1 Y 1 R LEU 170  ? E LEU 708  
757 1 Y 1 R LYS 288  ? E LYS 826  
758 1 Y 1 R GLY 289  ? E GLY 827  
759 1 Y 1 R LYS 290  ? E LYS 828  
760 1 Y 1 R CYS 291  ? E CYS 829  
761 1 Y 1 R GLY 292  ? E GLY 830  
762 1 Y 1 R SER 293  ? E SER 831  
763 1 Y 1 R GLY 294  ? E GLY 832  
764 1 Y 1 R SER 295  ? E SER 833  
765 1 Y 1 R GLY 296  ? E GLY 834  
766 1 Y 1 R GLY 297  ? E GLY 835  
767 1 Y 1 R SER 298  ? E SER 836  
768 1 Y 1 R GLY 299  ? E GLY 837  
769 1 Y 1 R SER 300  ? E SER 838  
770 1 Y 1 R GLY 301  ? E GLY 839  
771 1 Y 1 R GLY 302  ? E GLY 840  
772 1 Y 1 R SER 303  ? E SER 841  
773 1 Y 1 R GLY 304  ? E GLY 842  
774 1 Y 1 R SER 305  ? E SER 843  
775 1 Y 1 R GLY 306  ? E GLY 844  
776 1 Y 1 R GLY 307  ? E GLY 845  
777 1 Y 1 R SER 308  ? E SER 846  
778 1 Y 1 R GLY 309  ? E GLY 847  
779 1 Y 1 R SER 310  ? E SER 848  
780 1 Y 1 R GLY 311  ? E GLY 849  
781 1 Y 1 R SER 312  ? E SER 850  
782 1 Y 1 R SER 313  ? E SER 851  
783 1 Y 1 R GLY 314  ? E GLY 852  
784 1 Y 1 R GLY 315  ? E GLY 853  
785 1 Y 1 R VAL 316  ? E VAL 854  
786 1 Y 1 R PHE 317  ? E PHE 855  
787 1 Y 1 R THR 318  ? E THR 856  
788 1 Y 1 R LEU 319  ? E LEU 857  
789 1 Y 1 R GLU 320  ? E GLU 858  
790 1 Y 1 R ASP 321  ? E ASP 859  
791 1 Y 1 R PHE 322  ? E PHE 860  
792 1 Y 1 R VAL 323  ? E VAL 861  
793 1 Y 1 R GLY 324  ? E GLY 862  
794 1 Y 1 R ASP 325  ? E ASP 863  
795 1 Y 1 R TRP 326  ? E TRP 864  
796 1 Y 1 R GLU 327  ? E GLU 865  
797 1 Y 1 R GLN 328  ? E GLN 866  
798 1 Y 1 R THR 329  ? E THR 867  
799 1 Y 1 R ALA 330  ? E ALA 868  
800 1 Y 1 R ALA 331  ? E ALA 869  
801 1 Y 1 R TYR 332  ? E TYR 870  
802 1 Y 1 R ASN 333  ? E ASN 871  
803 1 Y 1 R LEU 334  ? E LEU 872  
804 1 Y 1 R ASP 335  ? E ASP 873  
805 1 Y 1 R GLN 336  ? E GLN 874  
806 1 Y 1 R VAL 337  ? E VAL 875  
807 1 Y 1 R LEU 338  ? E LEU 876  
808 1 Y 1 R GLU 339  ? E GLU 877  
809 1 Y 1 R GLN 340  ? E GLN 878  
810 1 Y 1 R GLY 341  ? E GLY 879  
811 1 Y 1 R GLY 342  ? E GLY 880  
812 1 Y 1 R VAL 343  ? E VAL 881  
813 1 Y 1 R SER 344  ? E SER 882  
814 1 Y 1 R SER 345  ? E SER 883  
815 1 Y 1 R LEU 346  ? E LEU 884  
816 1 Y 1 R LEU 347  ? E LEU 885  
817 1 Y 1 R GLN 348  ? E GLN 886  
818 1 Y 1 R ASN 349  ? E ASN 887  
819 1 Y 1 R LEU 350  ? E LEU 888  
820 1 Y 1 R ALA 351  ? E ALA 889  
821 1 Y 1 R VAL 352  ? E VAL 890  
822 1 Y 1 R SER 353  ? E SER 891  
823 1 Y 1 R VAL 354  ? E VAL 892  
824 1 Y 1 R THR 355  ? E THR 893  
825 1 Y 1 R PRO 356  ? E PRO 894  
826 1 Y 1 R ILE 357  ? E ILE 895  
827 1 Y 1 R GLN 358  ? E GLN 896  
828 1 Y 1 R ARG 359  ? E ARG 897  
829 1 Y 1 R ILE 360  ? E ILE 898  
830 1 Y 1 R VAL 361  ? E VAL 899  
831 1 Y 1 R ARG 362  ? E ARG 900  
832 1 Y 1 R SER 363  ? E SER 901  
833 1 Y 1 R GLY 364  ? E GLY 902  
834 1 Y 1 R GLU 365  ? E GLU 903  
835 1 Y 1 R ASN 366  ? E ASN 904  
836 1 Y 1 R ALA 367  ? E ALA 905  
837 1 Y 1 R LEU 368  ? E LEU 906  
838 1 Y 1 R LYS 369  ? E LYS 907  
839 1 Y 1 R ILE 370  ? E ILE 908  
840 1 Y 1 R ASP 371  ? E ASP 909  
841 1 Y 1 R ILE 372  ? E ILE 910  
842 1 Y 1 R HIS 373  ? E HIS 911  
843 1 Y 1 R VAL 374  ? E VAL 912  
844 1 Y 1 R ILE 375  ? E ILE 913  
845 1 Y 1 R ILE 376  ? E ILE 914  
846 1 Y 1 R PRO 377  ? E PRO 915  
847 1 Y 1 R TYR 378  ? E TYR 916  
848 1 Y 1 R GLU 379  ? E GLU 917  
849 1 Y 1 R GLY 380  ? E GLY 918  
850 1 Y 1 R LEU 381  ? E LEU 919  
851 1 Y 1 R SER 382  ? E SER 920  
852 1 Y 1 R ALA 383  ? E ALA 921  
853 1 Y 1 R ASP 384  ? E ASP 922  
854 1 Y 1 R GLN 385  ? E GLN 923  
855 1 Y 1 R MET 386  ? E MET 924  
856 1 Y 1 R ALA 387  ? E ALA 925  
857 1 Y 1 R GLN 388  ? E GLN 926  
858 1 Y 1 R ILE 389  ? E ILE 927  
859 1 Y 1 R GLU 390  ? E GLU 928  
860 1 Y 1 R GLU 391  ? E GLU 929  
861 1 Y 1 R VAL 392  ? E VAL 930  
862 1 Y 1 R PHE 393  ? E PHE 931  
863 1 Y 1 R LYS 394  ? E LYS 932  
864 1 Y 1 R VAL 395  ? E VAL 933  
865 1 Y 1 R VAL 396  ? E VAL 934  
866 1 Y 1 R TYR 397  ? E TYR 935  
867 1 Y 1 R PRO 398  ? E PRO 936  
868 1 Y 1 R VAL 399  ? E VAL 937  
869 1 Y 1 R ASP 400  ? E ASP 938  
870 1 Y 1 R ASP 401  ? E ASP 939  
871 1 Y 1 R HIS 402  ? E HIS 940  
872 1 Y 1 R HIS 403  ? E HIS 941  
873 1 Y 1 R PHE 404  ? E PHE 942  
874 1 Y 1 R LYS 405  ? E LYS 943  
875 1 Y 1 R VAL 406  ? E VAL 944  
876 1 Y 1 R ILE 407  ? E ILE 945  
877 1 Y 1 R LEU 408  ? E LEU 946  
878 1 Y 1 R PRO 409  ? E PRO 947  
879 1 Y 1 R TYR 410  ? E TYR 948  
880 1 Y 1 R GLY 411  ? E GLY 949  
881 1 Y 1 R THR 412  ? E THR 950  
882 1 Y 1 R LEU 413  ? E LEU 951  
883 1 Y 1 R VAL 414  ? E VAL 952  
884 1 Y 1 R ILE 415  ? E ILE 953  
885 1 Y 1 R ASP 416  ? E ASP 954  
886 1 Y 1 R GLY 417  ? E GLY 955  
887 1 Y 1 R VAL 418  ? E VAL 956  
888 1 Y 1 R THR 419  ? E THR 957  
889 1 Y 1 R PRO 420  ? E PRO 958  
890 1 Y 1 R ASN 421  ? E ASN 959  
891 1 Y 1 R MET 422  ? E MET 960  
892 1 Y 1 R LEU 423  ? E LEU 961  
893 1 Y 1 R ASN 424  ? E ASN 962  
894 1 Y 1 R TYR 425  ? E TYR 963  
895 1 Y 1 R PHE 426  ? E PHE 964  
896 1 Y 1 R GLY 427  ? E GLY 965  
897 1 Y 1 R ARG 428  ? E ARG 966  
898 1 Y 1 R PRO 429  ? E PRO 967  
899 1 Y 1 R TYR 430  ? E TYR 968  
900 1 Y 1 R GLU 431  ? E GLU 969  
901 1 Y 1 R GLY 432  ? E GLY 970  
902 1 Y 1 R ILE 433  ? E ILE 971  
903 1 Y 1 R ALA 434  ? E ALA 972  
904 1 Y 1 R VAL 435  ? E VAL 973  
905 1 Y 1 R PHE 436  ? E PHE 974  
906 1 Y 1 R ASP 437  ? E ASP 975  
907 1 Y 1 R GLY 438  ? E GLY 976  
908 1 Y 1 R LYS 439  ? E LYS 977  
909 1 Y 1 R LYS 440  ? E LYS 978  
910 1 Y 1 R ILE 441  ? E ILE 979  
911 1 Y 1 R THR 442  ? E THR 980  
912 1 Y 1 R VAL 443  ? E VAL 981  
913 1 Y 1 R THR 444  ? E THR 982  
914 1 Y 1 R GLY 445  ? E GLY 983  
915 1 Y 1 R THR 446  ? E THR 984  
916 1 Y 1 R LEU 447  ? E LEU 985  
917 1 Y 1 R TRP 448  ? E TRP 986  
918 1 Y 1 R ASN 449  ? E ASN 987  
919 1 Y 1 R GLY 450  ? E GLY 988  
920 1 Y 1 R ASN 451  ? E ASN 989  
921 1 Y 1 R LYS 452  ? E LYS 990  
922 1 Y 1 R ILE 453  ? E ILE 991  
923 1 Y 1 R ILE 454  ? E ILE 992  
924 1 Y 1 R ASP 455  ? E ASP 993  
925 1 Y 1 R GLU 456  ? E GLU 994  
926 1 Y 1 R ARG 457  ? E ARG 995  
927 1 Y 1 R LEU 458  ? E LEU 996  
928 1 Y 1 R ILE 459  ? E ILE 997  
929 1 Y 1 R THR 460  ? E THR 998  
930 1 Y 1 R PRO 461  ? E PRO 999  
931 1 Y 1 R ASP 462  ? E ASP 1000 
932 1 Y 1 R GLY 463  ? E GLY 1001 
933 1 Y 1 R SER 464  ? E SER 1002 
934 1 Y 1 R MET 465  ? E MET 1003 
935 1 Y 1 R LEU 466  ? E LEU 1004 
936 1 Y 1 R PHE 467  ? E PHE 1005 
937 1 Y 1 R ARG 468  ? E ARG 1006 
938 1 Y 1 R VAL 469  ? E VAL 1007 
939 1 Y 1 R THR 470  ? E THR 1008 
940 1 Y 1 R ILE 471  ? E ILE 1009 
941 1 Y 1 R ASN 472  ? E ASN 1010 
942 1 Y 1 R SER 473  ? E SER 1011 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SA0 C1   C N S 287 
SA0 O1   O N N 288 
SA0 C2   C N R 289 
SA0 O2   O N N 290 
SA0 C3   C N S 291 
SA0 O3   O N N 292 
SA0 C4   C N S 293 
SA0 O4   O N N 294 
SA0 C5   C N R 295 
SA0 O5   O N N 296 
SA0 C6   C N N 297 
SA0 O6   O N N 298 
SA0 OAA  O N N 299 
SA0 CAF  C Y N 300 
SA0 CAG  C Y N 301 
SA0 CAH  C Y N 302 
SA0 CAI  C Y N 303 
SA0 CAJ  C N N 304 
SA0 CAN  C Y N 305 
SA0 CAO  C Y N 306 
SA0 H1   H N N 307 
SA0 H2   H N N 308 
SA0 HO2  H N N 309 
SA0 H3   H N N 310 
SA0 HO3  H N N 311 
SA0 H4   H N N 312 
SA0 HO4  H N N 313 
SA0 H5   H N N 314 
SA0 H61  H N N 315 
SA0 H62  H N N 316 
SA0 HO6  H N N 317 
SA0 HOAA H N N 318 
SA0 HAF  H N N 319 
SA0 HAG  H N N 320 
SA0 HAH  H N N 321 
SA0 HAI  H N N 322 
SA0 HAJ  H N N 323 
SA0 HAJA H N N 324 
SER N    N N N 325 
SER CA   C N S 326 
SER C    C N N 327 
SER O    O N N 328 
SER CB   C N N 329 
SER OG   O N N 330 
SER OXT  O N N 331 
SER H    H N N 332 
SER H2   H N N 333 
SER HA   H N N 334 
SER HB2  H N N 335 
SER HB3  H N N 336 
SER HG   H N N 337 
SER HXT  H N N 338 
THR N    N N N 339 
THR CA   C N S 340 
THR C    C N N 341 
THR O    O N N 342 
THR CB   C N R 343 
THR OG1  O N N 344 
THR CG2  C N N 345 
THR OXT  O N N 346 
THR H    H N N 347 
THR H2   H N N 348 
THR HA   H N N 349 
THR HB   H N N 350 
THR HG1  H N N 351 
THR HG21 H N N 352 
THR HG22 H N N 353 
THR HG23 H N N 354 
THR HXT  H N N 355 
TRP N    N N N 356 
TRP CA   C N S 357 
TRP C    C N N 358 
TRP O    O N N 359 
TRP CB   C N N 360 
TRP CG   C Y N 361 
TRP CD1  C Y N 362 
TRP CD2  C Y N 363 
TRP NE1  N Y N 364 
TRP CE2  C Y N 365 
TRP CE3  C Y N 366 
TRP CZ2  C Y N 367 
TRP CZ3  C Y N 368 
TRP CH2  C Y N 369 
TRP OXT  O N N 370 
TRP H    H N N 371 
TRP H2   H N N 372 
TRP HA   H N N 373 
TRP HB2  H N N 374 
TRP HB3  H N N 375 
TRP HD1  H N N 376 
TRP HE1  H N N 377 
TRP HE3  H N N 378 
TRP HZ2  H N N 379 
TRP HZ3  H N N 380 
TRP HH2  H N N 381 
TRP HXT  H N N 382 
TYR N    N N N 383 
TYR CA   C N S 384 
TYR C    C N N 385 
TYR O    O N N 386 
TYR CB   C N N 387 
TYR CG   C Y N 388 
TYR CD1  C Y N 389 
TYR CD2  C Y N 390 
TYR CE1  C Y N 391 
TYR CE2  C Y N 392 
TYR CZ   C Y N 393 
TYR OH   O N N 394 
TYR OXT  O N N 395 
TYR H    H N N 396 
TYR H2   H N N 397 
TYR HA   H N N 398 
TYR HB2  H N N 399 
TYR HB3  H N N 400 
TYR HD1  H N N 401 
TYR HD2  H N N 402 
TYR HE1  H N N 403 
TYR HE2  H N N 404 
TYR HH   H N N 405 
TYR HXT  H N N 406 
VAL N    N N N 407 
VAL CA   C N S 408 
VAL C    C N N 409 
VAL O    O N N 410 
VAL CB   C N N 411 
VAL CG1  C N N 412 
VAL CG2  C N N 413 
VAL OXT  O N N 414 
VAL H    H N N 415 
VAL H2   H N N 416 
VAL HA   H N N 417 
VAL HB   H N N 418 
VAL HG11 H N N 419 
VAL HG12 H N N 420 
VAL HG13 H N N 421 
VAL HG21 H N N 422 
VAL HG22 H N N 423 
VAL HG23 H N N 424 
VAL HXT  H N N 425 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SA0 C1  O1   sing N N 275 
SA0 C1  C2   sing N N 276 
SA0 C1  O5   sing N N 277 
SA0 O1  CAO  sing N N 278 
SA0 C2  O2   sing N N 279 
SA0 C2  C3   sing N N 280 
SA0 C3  O3   sing N N 281 
SA0 C3  C4   sing N N 282 
SA0 C4  O4   sing N N 283 
SA0 C4  C5   sing N N 284 
SA0 C5  O5   sing N N 285 
SA0 C5  C6   sing N N 286 
SA0 C6  O6   sing N N 287 
SA0 OAA CAJ  sing N N 288 
SA0 CAF CAG  doub Y N 289 
SA0 CAF CAH  sing Y N 290 
SA0 CAG CAI  sing Y N 291 
SA0 CAH CAN  doub Y N 292 
SA0 CAI CAO  doub Y N 293 
SA0 CAJ CAN  sing N N 294 
SA0 CAN CAO  sing Y N 295 
SA0 C1  H1   sing N N 296 
SA0 C2  H2   sing N N 297 
SA0 O2  HO2  sing N N 298 
SA0 C3  H3   sing N N 299 
SA0 O3  HO3  sing N N 300 
SA0 C4  H4   sing N N 301 
SA0 O4  HO4  sing N N 302 
SA0 C5  H5   sing N N 303 
SA0 C6  H61  sing N N 304 
SA0 C6  H62  sing N N 305 
SA0 O6  HO6  sing N N 306 
SA0 OAA HOAA sing N N 307 
SA0 CAF HAF  sing N N 308 
SA0 CAG HAG  sing N N 309 
SA0 CAH HAH  sing N N 310 
SA0 CAI HAI  sing N N 311 
SA0 CAJ HAJ  sing N N 312 
SA0 CAJ HAJA sing N N 313 
SER N   CA   sing N N 314 
SER N   H    sing N N 315 
SER N   H2   sing N N 316 
SER CA  C    sing N N 317 
SER CA  CB   sing N N 318 
SER CA  HA   sing N N 319 
SER C   O    doub N N 320 
SER C   OXT  sing N N 321 
SER CB  OG   sing N N 322 
SER CB  HB2  sing N N 323 
SER CB  HB3  sing N N 324 
SER OG  HG   sing N N 325 
SER OXT HXT  sing N N 326 
THR N   CA   sing N N 327 
THR N   H    sing N N 328 
THR N   H2   sing N N 329 
THR CA  C    sing N N 330 
THR CA  CB   sing N N 331 
THR CA  HA   sing N N 332 
THR C   O    doub N N 333 
THR C   OXT  sing N N 334 
THR CB  OG1  sing N N 335 
THR CB  CG2  sing N N 336 
THR CB  HB   sing N N 337 
THR OG1 HG1  sing N N 338 
THR CG2 HG21 sing N N 339 
THR CG2 HG22 sing N N 340 
THR CG2 HG23 sing N N 341 
THR OXT HXT  sing N N 342 
TRP N   CA   sing N N 343 
TRP N   H    sing N N 344 
TRP N   H2   sing N N 345 
TRP CA  C    sing N N 346 
TRP CA  CB   sing N N 347 
TRP CA  HA   sing N N 348 
TRP C   O    doub N N 349 
TRP C   OXT  sing N N 350 
TRP CB  CG   sing N N 351 
TRP CB  HB2  sing N N 352 
TRP CB  HB3  sing N N 353 
TRP CG  CD1  doub Y N 354 
TRP CG  CD2  sing Y N 355 
TRP CD1 NE1  sing Y N 356 
TRP CD1 HD1  sing N N 357 
TRP CD2 CE2  doub Y N 358 
TRP CD2 CE3  sing Y N 359 
TRP NE1 CE2  sing Y N 360 
TRP NE1 HE1  sing N N 361 
TRP CE2 CZ2  sing Y N 362 
TRP CE3 CZ3  doub Y N 363 
TRP CE3 HE3  sing N N 364 
TRP CZ2 CH2  doub Y N 365 
TRP CZ2 HZ2  sing N N 366 
TRP CZ3 CH2  sing Y N 367 
TRP CZ3 HZ3  sing N N 368 
TRP CH2 HH2  sing N N 369 
TRP OXT HXT  sing N N 370 
TYR N   CA   sing N N 371 
TYR N   H    sing N N 372 
TYR N   H2   sing N N 373 
TYR CA  C    sing N N 374 
TYR CA  CB   sing N N 375 
TYR CA  HA   sing N N 376 
TYR C   O    doub N N 377 
TYR C   OXT  sing N N 378 
TYR CB  CG   sing N N 379 
TYR CB  HB2  sing N N 380 
TYR CB  HB3  sing N N 381 
TYR CG  CD1  doub Y N 382 
TYR CG  CD2  sing Y N 383 
TYR CD1 CE1  sing Y N 384 
TYR CD1 HD1  sing N N 385 
TYR CD2 CE2  doub Y N 386 
TYR CD2 HD2  sing N N 387 
TYR CE1 CZ   doub Y N 388 
TYR CE1 HE1  sing N N 389 
TYR CE2 CZ   sing Y N 390 
TYR CE2 HE2  sing N N 391 
TYR CZ  OH   sing N N 392 
TYR OH  HH   sing N N 393 
TYR OXT HXT  sing N N 394 
VAL N   CA   sing N N 395 
VAL N   H    sing N N 396 
VAL N   H2   sing N N 397 
VAL CA  C    sing N N 398 
VAL CA  CB   sing N N 399 
VAL CA  HA   sing N N 400 
VAL C   O    doub N N 401 
VAL C   OXT  sing N N 402 
VAL CB  CG1  sing N N 403 
VAL CB  CG2  sing N N 404 
VAL CB  HB   sing N N 405 
VAL CG1 HG11 sing N N 406 
VAL CG1 HG12 sing N N 407 
VAL CG1 HG13 sing N N 408 
VAL CG2 HG21 sing N N 409 
VAL CG2 HG22 sing N N 410 
VAL CG2 HG23 sing N N 411 
VAL OXT HXT  sing N N 412 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-10-22 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9K6L 
_em_admin.last_update        2025-04-02 
_em_admin.map_release_date   2025-04-02 
_em_admin.title              'Cryo-EM structure of GPCR16-Gi2 complex' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING ONLY' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOCONTINUUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9K6L 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . THR A 1 4   ? 146.440 155.351 115.953 1.00 95.13  ? 4   THR A N   1 
ATOM   2    C CA  . THR A 1 4   ? 145.279 156.188 115.678 1.00 96.36  ? 4   THR A CA  1 
ATOM   3    C C   . THR A 1 4   ? 144.274 155.439 114.808 1.00 99.62  ? 4   THR A C   1 
ATOM   4    O O   . THR A 1 4   ? 144.655 154.664 113.932 1.00 101.09 ? 4   THR A O   1 
ATOM   5    C CB  . THR A 1 4   ? 145.684 157.501 114.983 1.00 95.86  ? 4   THR A CB  1 
ATOM   6    O OG1 . THR A 1 4   ? 146.834 158.051 115.635 1.00 97.70  ? 4   THR A OG1 1 
ATOM   7    C CG2 . THR A 1 4   ? 144.550 158.511 115.047 1.00 92.54  ? 4   THR A CG2 1 
ATOM   8    N N   . VAL A 1 5   ? 142.989 155.674 115.058 1.00 88.39  ? 5   VAL A N   1 
ATOM   9    C CA  . VAL A 1 5   ? 141.901 155.011 114.348 1.00 84.78  ? 5   VAL A CA  1 
ATOM   10   C C   . VAL A 1 5   ? 141.219 156.034 113.452 1.00 84.75  ? 5   VAL A C   1 
ATOM   11   O O   . VAL A 1 5   ? 140.910 157.147 113.895 1.00 88.01  ? 5   VAL A O   1 
ATOM   12   C CB  . VAL A 1 5   ? 140.899 154.379 115.328 1.00 84.69  ? 5   VAL A CB  1 
ATOM   13   C CG1 . VAL A 1 5   ? 139.974 153.426 114.601 1.00 85.76  ? 5   VAL A CG1 1 
ATOM   14   C CG2 . VAL A 1 5   ? 141.635 153.659 116.442 1.00 85.14  ? 5   VAL A CG2 1 
ATOM   15   N N   . SER A 1 6   ? 140.987 155.659 112.196 1.00 74.01  ? 6   SER A N   1 
ATOM   16   C CA  . SER A 1 6   ? 140.339 156.553 111.249 1.00 70.80  ? 6   SER A CA  1 
ATOM   17   C C   . SER A 1 6   ? 138.896 156.823 111.670 1.00 74.71  ? 6   SER A C   1 
ATOM   18   O O   . SER A 1 6   ? 138.353 156.194 112.579 1.00 83.28  ? 6   SER A O   1 
ATOM   19   C CB  . SER A 1 6   ? 140.370 155.958 109.844 1.00 79.32  ? 6   SER A CB  1 
ATOM   20   O OG  . SER A 1 6   ? 141.676 155.541 109.491 1.00 80.55  ? 6   SER A OG  1 
ATOM   21   N N   . ALA A 1 7   ? 138.273 157.785 110.987 1.00 68.17  ? 7   ALA A N   1 
ATOM   22   C CA  . ALA A 1 7   ? 136.903 158.157 111.322 1.00 72.37  ? 7   ALA A CA  1 
ATOM   23   C C   . ALA A 1 7   ? 135.944 156.999 111.081 1.00 75.20  ? 7   ALA A C   1 
ATOM   24   O O   . ALA A 1 7   ? 135.206 156.583 111.985 1.00 82.48  ? 7   ALA A O   1 
ATOM   25   C CB  . ALA A 1 7   ? 136.483 159.382 110.511 1.00 70.34  ? 7   ALA A CB  1 
ATOM   26   N N   . GLU A 1 8   ? 135.961 156.437 109.878 1.00 81.35  ? 8   GLU A N   1 
ATOM   27   C CA  . GLU A 1 8   ? 135.090 155.303 109.620 1.00 86.23  ? 8   GLU A CA  1 
ATOM   28   C C   . GLU A 1 8   ? 135.717 153.977 110.010 1.00 84.34  ? 8   GLU A C   1 
ATOM   29   O O   . GLU A 1 8   ? 135.005 152.978 110.067 1.00 89.56  ? 8   GLU A O   1 
ATOM   30   C CB  . GLU A 1 8   ? 134.657 155.264 108.155 1.00 87.88  ? 8   GLU A CB  1 
ATOM   31   C CG  . GLU A 1 8   ? 135.602 154.564 107.233 1.00 89.23  ? 8   GLU A CG  1 
ATOM   32   C CD  . GLU A 1 8   ? 136.663 155.498 106.747 1.00 89.90  ? 8   GLU A CD  1 
ATOM   33   O OE1 . GLU A 1 8   ? 137.390 156.040 107.602 1.00 89.90  ? 8   GLU A OE1 1 
ATOM   34   O OE2 . GLU A 1 8   ? 136.751 155.708 105.519 1.00 86.79  ? 8   GLU A OE2 1 
ATOM   35   N N   . ASP A 1 9   ? 137.011 153.940 110.327 1.00 74.33  ? 9   ASP A N   1 
ATOM   36   C CA  . ASP A 1 9   ? 137.517 152.803 111.086 1.00 74.96  ? 9   ASP A CA  1 
ATOM   37   C C   . ASP A 1 9   ? 136.871 152.759 112.465 1.00 73.86  ? 9   ASP A C   1 
ATOM   38   O O   . ASP A 1 9   ? 136.464 151.692 112.940 1.00 82.25  ? 9   ASP A O   1 
ATOM   39   C CB  . ASP A 1 9   ? 139.037 152.870 111.197 1.00 79.29  ? 9   ASP A CB  1 
ATOM   40   C CG  . ASP A 1 9   ? 139.729 151.853 110.316 1.00 88.19  ? 9   ASP A CG  1 
ATOM   41   O OD1 . ASP A 1 9   ? 139.028 151.018 109.709 1.00 88.98  ? 9   ASP A OD1 1 
ATOM   42   O OD2 . ASP A 1 9   ? 140.974 151.886 110.231 1.00 90.95  ? 9   ASP A OD2 1 
ATOM   43   N N   . LYS A 1 10  ? 136.742 153.920 113.108 1.00 67.03  ? 10  LYS A N   1 
ATOM   44   C CA  . LYS A 1 10  ? 135.991 154.004 114.355 1.00 64.88  ? 10  LYS A CA  1 
ATOM   45   C C   . LYS A 1 10  ? 134.526 153.652 114.137 1.00 65.01  ? 10  LYS A C   1 
ATOM   46   O O   . LYS A 1 10  ? 133.910 152.974 114.969 1.00 72.73  ? 10  LYS A O   1 
ATOM   47   C CB  . LYS A 1 10  ? 136.122 155.406 114.945 1.00 68.38  ? 10  LYS A CB  1 
ATOM   48   C CG  . LYS A 1 10  ? 136.240 155.446 116.455 1.00 73.02  ? 10  LYS A CG  1 
ATOM   49   C CD  . LYS A 1 10  ? 136.234 156.878 116.958 1.00 72.17  ? 10  LYS A CD  1 
ATOM   50   C CE  . LYS A 1 10  ? 137.504 157.605 116.554 1.00 74.07  ? 10  LYS A CE  1 
ATOM   51   N NZ  . LYS A 1 10  ? 137.310 159.080 116.511 1.00 72.22  ? 10  LYS A NZ  1 
ATOM   52   N N   . ALA A 1 11  ? 133.946 154.111 113.026 1.00 65.89  ? 11  ALA A N   1 
ATOM   53   C CA  . ALA A 1 11  ? 132.554 153.779 112.739 1.00 67.86  ? 11  ALA A CA  1 
ATOM   54   C C   . ALA A 1 11  ? 132.372 152.280 112.519 1.00 71.42  ? 11  ALA A C   1 
ATOM   55   O O   . ALA A 1 11  ? 131.364 151.701 112.938 1.00 77.08  ? 11  ALA A O   1 
ATOM   56   C CB  . ALA A 1 11  ? 132.065 154.567 111.527 1.00 71.27  ? 11  ALA A CB  1 
ATOM   57   N N   . ALA A 1 12  ? 133.337 151.633 111.864 1.00 66.12  ? 12  ALA A N   1 
ATOM   58   C CA  . ALA A 1 12  ? 133.278 150.190 111.671 1.00 56.24  ? 12  ALA A CA  1 
ATOM   59   C C   . ALA A 1 12  ? 133.461 149.452 112.987 1.00 60.32  ? 12  ALA A C   1 
ATOM   60   O O   . ALA A 1 12  ? 132.856 148.399 113.202 1.00 75.42  ? 12  ALA A O   1 
ATOM   61   C CB  . ALA A 1 12  ? 134.334 149.753 110.660 1.00 59.01  ? 12  ALA A CB  1 
ATOM   62   N N   . ALA A 1 13  ? 134.297 149.985 113.879 1.00 59.21  ? 13  ALA A N   1 
ATOM   63   C CA  . ALA A 1 13  ? 134.400 149.410 115.215 1.00 58.11  ? 13  ALA A CA  1 
ATOM   64   C C   . ALA A 1 13  ? 133.073 149.508 115.954 1.00 57.06  ? 13  ALA A C   1 
ATOM   65   O O   . ALA A 1 13  ? 132.664 148.569 116.646 1.00 62.67  ? 13  ALA A O   1 
ATOM   66   C CB  . ALA A 1 13  ? 135.510 150.103 116.002 1.00 60.89  ? 13  ALA A CB  1 
ATOM   67   N N   . GLU A 1 14  ? 132.381 150.639 115.817 1.00 64.71  ? 14  GLU A N   1 
ATOM   68   C CA  . GLU A 1 14  ? 131.073 150.778 116.451 1.00 65.88  ? 14  GLU A CA  1 
ATOM   69   C C   . GLU A 1 14  ? 130.059 149.821 115.835 1.00 69.97  ? 14  GLU A C   1 
ATOM   70   O O   . GLU A 1 14  ? 129.215 149.258 116.542 1.00 82.72  ? 14  GLU A O   1 
ATOM   71   C CB  . GLU A 1 14  ? 130.582 152.219 116.344 1.00 66.56  ? 14  GLU A CB  1 
ATOM   72   C CG  . GLU A 1 14  ? 129.081 152.354 116.491 1.00 73.15  ? 14  GLU A CG  1 
ATOM   73   C CD  . GLU A 1 14  ? 128.625 153.791 116.513 1.00 82.51  ? 14  GLU A CD  1 
ATOM   74   O OE1 . GLU A 1 14  ? 127.398 154.021 116.533 1.00 87.45  ? 14  GLU A OE1 1 
ATOM   75   O OE2 . GLU A 1 14  ? 129.491 154.688 116.498 1.00 81.13  ? 14  GLU A OE2 1 
ATOM   76   N N   . ARG A 1 15  ? 130.122 149.635 114.517 1.00 57.09  ? 15  ARG A N   1 
ATOM   77   C CA  . ARG A 1 15  ? 129.257 148.661 113.858 1.00 54.27  ? 15  ARG A CA  1 
ATOM   78   C C   . ARG A 1 15  ? 129.536 147.253 114.365 1.00 60.01  ? 15  ARG A C   1 
ATOM   79   O O   . ARG A 1 15  ? 128.609 146.466 114.582 1.00 68.90  ? 15  ARG A O   1 
ATOM   80   C CB  . ARG A 1 15  ? 129.447 148.741 112.345 1.00 55.20  ? 15  ARG A CB  1 
ATOM   81   C CG  . ARG A 1 15  ? 128.819 147.606 111.561 1.00 58.58  ? 15  ARG A CG  1 
ATOM   82   C CD  . ARG A 1 15  ? 129.217 147.685 110.098 1.00 60.64  ? 15  ARG A CD  1 
ATOM   83   N NE  . ARG A 1 15  ? 128.748 146.545 109.323 1.00 57.50  ? 15  ARG A NE  1 
ATOM   84   C CZ  . ARG A 1 15  ? 127.503 146.387 108.900 1.00 56.44  ? 15  ARG A CZ  1 
ATOM   85   N NH1 . ARG A 1 15  ? 126.564 147.280 109.166 1.00 57.75  ? 15  ARG A NH1 1 
ATOM   86   N NH2 . ARG A 1 15  ? 127.191 145.309 108.189 1.00 58.97  ? 15  ARG A NH2 1 
ATOM   87   N N   . SER A 1 16  ? 130.812 146.921 114.561 1.00 56.12  ? 16  SER A N   1 
ATOM   88   C CA  . SER A 1 16  ? 131.168 145.630 115.137 1.00 48.74  ? 16  SER A CA  1 
ATOM   89   C C   . SER A 1 16  ? 130.630 145.494 116.554 1.00 54.02  ? 16  SER A C   1 
ATOM   90   O O   . SER A 1 16  ? 130.192 144.413 116.955 1.00 67.06  ? 16  SER A O   1 
ATOM   91   C CB  . SER A 1 16  ? 132.684 145.450 115.121 1.00 51.07  ? 16  SER A CB  1 
ATOM   92   O OG  . SER A 1 16  ? 133.048 144.189 115.650 1.00 57.80  ? 16  SER A OG  1 
ATOM   93   N N   . LYS A 1 17  ? 130.664 146.578 117.331 1.00 68.00  ? 17  LYS A N   1 
ATOM   94   C CA  . LYS A 1 17  ? 130.097 146.538 118.677 1.00 66.33  ? 17  LYS A CA  1 
ATOM   95   C C   . LYS A 1 17  ? 128.592 146.303 118.639 1.00 66.01  ? 17  LYS A C   1 
ATOM   96   O O   . LYS A 1 17  ? 128.052 145.545 119.454 1.00 72.34  ? 17  LYS A O   1 
ATOM   97   C CB  . LYS A 1 17  ? 130.417 147.832 119.422 1.00 65.76  ? 17  LYS A CB  1 
ATOM   98   C CG  . LYS A 1 17  ? 131.381 147.656 120.579 1.00 68.13  ? 17  LYS A CG  1 
ATOM   99   C CD  . LYS A 1 17  ? 132.050 148.969 120.943 1.00 73.77  ? 17  LYS A CD  1 
ATOM   100  C CE  . LYS A 1 17  ? 131.030 150.081 121.124 1.00 75.46  ? 17  LYS A CE  1 
ATOM   101  N NZ  . LYS A 1 17  ? 130.010 149.740 122.153 1.00 76.12  ? 17  LYS A NZ  1 
ATOM   102  N N   . MET A 1 18  ? 127.895 146.954 117.708 1.00 60.70  ? 18  MET A N   1 
ATOM   103  C CA  . MET A 1 18  ? 126.459 146.727 117.568 1.00 61.94  ? 18  MET A CA  1 
ATOM   104  C C   . MET A 1 18  ? 126.168 145.290 117.161 1.00 71.94  ? 18  MET A C   1 
ATOM   105  O O   . MET A 1 18  ? 125.219 144.669 117.660 1.00 78.44  ? 18  MET A O   1 
ATOM   106  C CB  . MET A 1 18  ? 125.867 147.697 116.549 1.00 62.77  ? 18  MET A CB  1 
ATOM   107  C CG  . MET A 1 18  ? 125.765 149.121 117.043 1.00 70.29  ? 18  MET A CG  1 
ATOM   108  S SD  . MET A 1 18  ? 124.279 149.927 116.425 1.00 92.85  ? 18  MET A SD  1 
ATOM   109  C CE  . MET A 1 18  ? 123.101 148.584 116.527 1.00 72.38  ? 18  MET A CE  1 
ATOM   110  N N   . ILE A 1 19  ? 126.972 144.746 116.249 1.00 67.41  ? 19  ILE A N   1 
ATOM   111  C CA  . ILE A 1 19  ? 126.793 143.360 115.839 1.00 60.10  ? 19  ILE A CA  1 
ATOM   112  C C   . ILE A 1 19  ? 127.075 142.424 117.007 1.00 63.06  ? 19  ILE A C   1 
ATOM   113  O O   . ILE A 1 19  ? 126.416 141.393 117.161 1.00 74.63  ? 19  ILE A O   1 
ATOM   114  C CB  . ILE A 1 19  ? 127.677 143.044 114.621 1.00 56.85  ? 19  ILE A CB  1 
ATOM   115  C CG1 . ILE A 1 19  ? 127.232 143.871 113.417 1.00 63.89  ? 19  ILE A CG1 1 
ATOM   116  C CG2 . ILE A 1 19  ? 127.570 141.593 114.260 1.00 64.10  ? 19  ILE A CG2 1 
ATOM   117  C CD1 . ILE A 1 19  ? 127.958 143.523 112.140 1.00 69.25  ? 19  ILE A CD1 1 
ATOM   118  N N   . ASP A 1 20  ? 128.048 142.771 117.853 1.00 64.67  ? 20  ASP A N   1 
ATOM   119  C CA  . ASP A 1 20  ? 128.307 141.992 119.061 1.00 62.69  ? 20  ASP A CA  1 
ATOM   120  C C   . ASP A 1 20  ? 127.118 142.027 120.008 1.00 64.69  ? 20  ASP A C   1 
ATOM   121  O O   . ASP A 1 20  ? 126.773 141.012 120.622 1.00 73.25  ? 20  ASP A O   1 
ATOM   122  C CB  . ASP A 1 20  ? 129.553 142.519 119.768 1.00 69.54  ? 20  ASP A CB  1 
ATOM   123  C CG  . ASP A 1 20  ? 130.822 142.203 119.019 1.00 76.52  ? 20  ASP A CG  1 
ATOM   124  O OD1 . ASP A 1 20  ? 130.776 141.347 118.118 1.00 72.72  ? 20  ASP A OD1 1 
ATOM   125  O OD2 . ASP A 1 20  ? 131.869 142.802 119.339 1.00 79.88  ? 20  ASP A OD2 1 
ATOM   126  N N   . LYS A 1 21  ? 126.499 143.196 120.164 1.00 66.67  ? 21  LYS A N   1 
ATOM   127  C CA  . LYS A 1 21  ? 125.322 143.298 121.018 1.00 65.99  ? 21  LYS A CA  1 
ATOM   128  C C   . LYS A 1 21  ? 124.190 142.428 120.489 1.00 69.48  ? 21  LYS A C   1 
ATOM   129  O O   . LYS A 1 21  ? 123.542 141.699 121.253 1.00 78.24  ? 21  LYS A O   1 
ATOM   130  C CB  . LYS A 1 21  ? 124.879 144.755 121.125 1.00 64.22  ? 21  LYS A CB  1 
ATOM   131  C CG  . LYS A 1 21  ? 123.481 144.945 121.679 1.00 70.64  ? 21  LYS A CG  1 
ATOM   132  C CD  . LYS A 1 21  ? 123.105 146.415 121.718 1.00 71.59  ? 21  LYS A CD  1 
ATOM   133  C CE  . LYS A 1 21  ? 121.598 146.603 121.680 1.00 75.87  ? 21  LYS A CE  1 
ATOM   134  N NZ  . LYS A 1 21  ? 120.932 145.597 120.808 1.00 74.98  ? 21  LYS A NZ  1 
ATOM   135  N N   . ASN A 1 22  ? 123.952 142.476 119.178 1.00 66.16  ? 22  ASN A N   1 
ATOM   136  C CA  . ASN A 1 22  ? 122.927 141.624 118.584 1.00 64.42  ? 22  ASN A CA  1 
ATOM   137  C C   . ASN A 1 22  ? 123.274 140.149 118.744 1.00 68.98  ? 22  ASN A C   1 
ATOM   138  O O   . ASN A 1 22  ? 122.398 139.324 119.028 1.00 79.17  ? 22  ASN A O   1 
ATOM   139  C CB  . ASN A 1 22  ? 122.739 141.974 117.110 1.00 68.41  ? 22  ASN A CB  1 
ATOM   140  C CG  . ASN A 1 22  ? 121.542 142.865 116.876 1.00 77.54  ? 22  ASN A CG  1 
ATOM   141  O OD1 . ASN A 1 22  ? 121.637 143.888 116.200 1.00 84.83  ? 22  ASN A OD1 1 
ATOM   142  N ND2 . ASN A 1 22  ? 120.402 142.482 117.439 1.00 74.77  ? 22  ASN A ND2 1 
ATOM   143  N N   . LEU A 1 23  ? 124.549 139.802 118.567 1.00 63.15  ? 23  LEU A N   1 
ATOM   144  C CA  . LEU A 1 23  ? 124.985 138.420 118.721 1.00 59.14  ? 23  LEU A CA  1 
ATOM   145  C C   . LEU A 1 23  ? 124.747 137.919 120.135 1.00 64.37  ? 23  LEU A C   1 
ATOM   146  O O   . LEU A 1 23  ? 124.262 136.801 120.328 1.00 75.28  ? 23  LEU A O   1 
ATOM   147  C CB  . LEU A 1 23  ? 126.466 138.299 118.372 1.00 60.37  ? 23  LEU A CB  1 
ATOM   148  C CG  . LEU A 1 23  ? 126.858 138.207 116.903 1.00 58.10  ? 23  LEU A CG  1 
ATOM   149  C CD1 . LEU A 1 23  ? 128.278 137.713 116.798 1.00 61.27  ? 23  LEU A CD1 1 
ATOM   150  C CD2 . LEU A 1 23  ? 125.921 137.285 116.169 1.00 62.13  ? 23  LEU A CD2 1 
ATOM   151  N N   . ARG A 1 24  ? 125.087 138.728 121.139 1.00 74.14  ? 24  ARG A N   1 
ATOM   152  C CA  . ARG A 1 24  ? 124.915 138.284 122.516 1.00 72.12  ? 24  ARG A CA  1 
ATOM   153  C C   . ARG A 1 24  ? 123.440 138.213 122.890 1.00 71.72  ? 24  ARG A C   1 
ATOM   154  O O   . ARG A 1 24  ? 123.030 137.312 123.630 1.00 81.57  ? 24  ARG A O   1 
ATOM   155  C CB  . ARG A 1 24  ? 125.693 139.186 123.477 1.00 71.21  ? 24  ARG A CB  1 
ATOM   156  C CG  . ARG A 1 24  ? 125.025 140.499 123.834 1.00 79.70  ? 24  ARG A CG  1 
ATOM   157  C CD  . ARG A 1 24  ? 125.825 141.243 124.889 1.00 81.31  ? 24  ARG A CD  1 
ATOM   158  N NE  . ARG A 1 24  ? 127.252 141.232 124.593 1.00 84.93  ? 24  ARG A NE  1 
ATOM   159  C CZ  . ARG A 1 24  ? 127.958 142.310 124.282 1.00 87.27  ? 24  ARG A CZ  1 
ATOM   160  N NH1 . ARG A 1 24  ? 127.401 143.508 124.223 1.00 85.03  ? 24  ARG A NH1 1 
ATOM   161  N NH2 . ARG A 1 24  ? 129.255 142.182 124.019 1.00 82.55  ? 24  ARG A NH2 1 
ATOM   162  N N   . GLU A 1 25  ? 122.618 139.128 122.370 1.00 67.41  ? 25  GLU A N   1 
ATOM   163  C CA  . GLU A 1 25  ? 121.187 139.040 122.638 1.00 71.81  ? 25  GLU A CA  1 
ATOM   164  C C   . GLU A 1 25  ? 120.609 137.775 122.016 1.00 79.80  ? 25  GLU A C   1 
ATOM   165  O O   . GLU A 1 25  ? 119.827 137.058 122.655 1.00 84.76  ? 25  GLU A O   1 
ATOM   166  C CB  . GLU A 1 25  ? 120.501 140.327 122.149 1.00 74.12  ? 25  GLU A CB  1 
ATOM   167  C CG  . GLU A 1 25  ? 118.957 140.502 122.277 1.00 78.93  ? 25  GLU A CG  1 
ATOM   168  C CD  . GLU A 1 25  ? 118.051 139.536 121.507 1.00 87.81  ? 25  GLU A CD  1 
ATOM   169  O OE1 . GLU A 1 25  ? 118.516 138.688 120.725 1.00 86.54  ? 25  GLU A OE1 1 
ATOM   170  O OE2 . GLU A 1 25  ? 116.822 139.638 121.702 1.00 92.32  ? 25  GLU A OE2 1 
ATOM   171  N N   . ASP A 1 26  ? 120.999 137.473 120.776 1.00 87.27  ? 26  ASP A N   1 
ATOM   172  C CA  . ASP A 1 26  ? 120.514 136.262 120.122 1.00 83.84  ? 26  ASP A CA  1 
ATOM   173  C C   . ASP A 1 26  ? 121.007 135.011 120.835 1.00 86.11  ? 26  ASP A C   1 
ATOM   174  O O   . ASP A 1 26  ? 120.266 134.033 120.962 1.00 93.00  ? 26  ASP A O   1 
ATOM   175  C CB  . ASP A 1 26  ? 120.940 136.250 118.657 1.00 87.16  ? 26  ASP A CB  1 
ATOM   176  C CG  . ASP A 1 26  ? 119.907 136.881 117.747 1.00 96.46  ? 26  ASP A CG  1 
ATOM   177  O OD1 . ASP A 1 26  ? 118.764 137.094 118.204 1.00 98.13  ? 26  ASP A OD1 1 
ATOM   178  O OD2 . ASP A 1 26  ? 120.235 137.166 116.577 1.00 98.29  ? 26  ASP A OD2 1 
ATOM   179  N N   . GLY A 1 27  ? 122.254 135.021 121.305 1.00 75.45  ? 27  GLY A N   1 
ATOM   180  C CA  . GLY A 1 27  ? 122.769 133.870 122.025 1.00 72.31  ? 27  GLY A CA  1 
ATOM   181  C C   . GLY A 1 27  ? 122.077 133.655 123.356 1.00 73.85  ? 27  GLY A C   1 
ATOM   182  O O   . GLY A 1 27  ? 121.836 132.516 123.761 1.00 79.98  ? 27  GLY A O   1 
ATOM   183  N N   . GLU A 1 28  ? 121.752 134.742 124.056 1.00 78.25  ? 28  GLU A N   1 
ATOM   184  C CA  . GLU A 1 28  ? 121.020 134.609 125.309 1.00 77.54  ? 28  GLU A CA  1 
ATOM   185  C C   . GLU A 1 28  ? 119.599 134.124 125.062 1.00 76.98  ? 28  GLU A C   1 
ATOM   186  O O   . GLU A 1 28  ? 119.045 133.371 125.872 1.00 82.40  ? 28  GLU A O   1 
ATOM   187  C CB  . GLU A 1 28  ? 121.019 135.936 126.061 1.00 77.38  ? 28  GLU A CB  1 
ATOM   188  C CG  . GLU A 1 28  ? 121.817 135.898 127.352 1.00 80.22  ? 28  GLU A CG  1 
ATOM   189  C CD  . GLU A 1 28  ? 122.266 137.272 127.799 1.00 84.01  ? 28  GLU A CD  1 
ATOM   190  O OE1 . GLU A 1 28  ? 121.409 138.174 127.903 1.00 86.66  ? 28  GLU A OE1 1 
ATOM   191  O OE2 . GLU A 1 28  ? 123.477 137.450 128.042 1.00 82.71  ? 28  GLU A OE2 1 
ATOM   192  N N   . LYS A 1 29  ? 118.988 134.546 123.954 1.00 68.43  ? 29  LYS A N   1 
ATOM   193  C CA  . LYS A 1 29  ? 117.675 134.016 123.603 1.00 68.91  ? 29  LYS A CA  1 
ATOM   194  C C   . LYS A 1 29  ? 117.752 132.538 123.237 1.00 69.10  ? 29  LYS A C   1 
ATOM   195  O O   . LYS A 1 29  ? 116.850 131.762 123.569 1.00 70.87  ? 29  LYS A O   1 
ATOM   196  C CB  . LYS A 1 29  ? 117.071 134.822 122.456 1.00 71.93  ? 29  LYS A CB  1 
ATOM   197  C CG  . LYS A 1 29  ? 115.608 135.160 122.650 1.00 73.29  ? 29  LYS A CG  1 
ATOM   198  C CD  . LYS A 1 29  ? 115.053 135.898 121.446 1.00 76.71  ? 29  LYS A CD  1 
ATOM   199  C CE  . LYS A 1 29  ? 114.672 134.933 120.337 1.00 79.35  ? 29  LYS A CE  1 
ATOM   200  N NZ  . LYS A 1 29  ? 113.440 134.166 120.666 1.00 80.57  ? 29  LYS A NZ  1 
ATOM   201  N N   . ALA A 1 30  ? 118.822 132.133 122.549 1.00 70.08  ? 30  ALA A N   1 
ATOM   202  C CA  . ALA A 1 30  ? 118.943 130.749 122.104 1.00 69.10  ? 30  ALA A CA  1 
ATOM   203  C C   . ALA A 1 30  ? 119.259 129.814 123.263 1.00 75.10  ? 30  ALA A C   1 
ATOM   204  O O   . ALA A 1 30  ? 118.772 128.679 123.302 1.00 84.23  ? 30  ALA A O   1 
ATOM   205  C CB  . ALA A 1 30  ? 120.015 130.639 121.021 1.00 72.20  ? 30  ALA A CB  1 
ATOM   206  N N   . ALA A 1 31  ? 120.079 130.262 124.213 1.00 69.21  ? 31  ALA A N   1 
ATOM   207  C CA  . ALA A 1 31  ? 120.374 129.444 125.381 1.00 70.04  ? 31  ALA A CA  1 
ATOM   208  C C   . ALA A 1 31  ? 119.164 129.264 126.284 1.00 66.49  ? 31  ALA A C   1 
ATOM   209  O O   . ALA A 1 31  ? 119.203 128.423 127.187 1.00 67.21  ? 31  ALA A O   1 
ATOM   210  C CB  . ALA A 1 31  ? 121.527 130.055 126.176 1.00 68.22  ? 31  ALA A CB  1 
ATOM   211  N N   . ARG A 1 32  ? 118.100 130.031 126.063 1.00 73.41  ? 32  ARG A N   1 
ATOM   212  C CA  . ARG A 1 32  ? 116.884 129.927 126.853 1.00 70.61  ? 32  ARG A CA  1 
ATOM   213  C C   . ARG A 1 32  ? 115.950 128.838 126.348 1.00 75.75  ? 32  ARG A C   1 
ATOM   214  O O   . ARG A 1 32  ? 115.036 128.439 127.076 1.00 78.18  ? 32  ARG A O   1 
ATOM   215  C CB  . ARG A 1 32  ? 116.160 131.272 126.839 1.00 77.90  ? 32  ARG A CB  1 
ATOM   216  C CG  . ARG A 1 32  ? 115.110 131.455 127.916 1.00 80.87  ? 32  ARG A CG  1 
ATOM   217  C CD  . ARG A 1 32  ? 114.567 132.888 127.910 1.00 83.48  ? 32  ARG A CD  1 
ATOM   218  N NE  . ARG A 1 32  ? 115.550 133.976 127.874 1.00 87.00  ? 32  ARG A NE  1 
ATOM   219  C CZ  . ARG A 1 32  ? 116.738 134.012 128.474 1.00 88.64  ? 32  ARG A CZ  1 
ATOM   220  N NH1 . ARG A 1 32  ? 117.135 133.062 129.307 1.00 85.57  ? 32  ARG A NH1 1 
ATOM   221  N NH2 . ARG A 1 32  ? 117.537 135.052 128.258 1.00 85.36  ? 32  ARG A NH2 1 
ATOM   222  N N   . GLU A 1 33  ? 116.161 128.349 125.133 1.00 84.84  ? 33  GLU A N   1 
ATOM   223  C CA  . GLU A 1 33  ? 115.306 127.343 124.526 1.00 83.92  ? 33  GLU A CA  1 
ATOM   224  C C   . GLU A 1 33  ? 115.900 125.954 124.718 1.00 87.52  ? 33  GLU A C   1 
ATOM   225  O O   . GLU A 1 33  ? 117.106 125.785 124.911 1.00 86.02  ? 33  GLU A O   1 
ATOM   226  C CB  . GLU A 1 33  ? 115.105 127.631 123.036 1.00 81.97  ? 33  GLU A CB  1 
ATOM   227  C CG  . GLU A 1 33  ? 116.274 127.216 122.166 1.00 87.04  ? 33  GLU A CG  1 
ATOM   228  C CD  . GLU A 1 33  ? 116.374 128.034 120.895 1.00 95.04  ? 33  GLU A CD  1 
ATOM   229  O OE1 . GLU A 1 33  ? 115.859 129.171 120.876 1.00 95.40  ? 33  GLU A OE1 1 
ATOM   230  O OE2 . GLU A 1 33  ? 116.979 127.544 119.920 1.00 96.12  ? 33  GLU A OE2 1 
ATOM   231  N N   . VAL A 1 34  ? 115.028 124.955 124.660 1.00 80.20  ? 34  VAL A N   1 
ATOM   232  C CA  . VAL A 1 34  ? 115.397 123.569 124.913 1.00 67.33  ? 34  VAL A CA  1 
ATOM   233  C C   . VAL A 1 34  ? 115.545 122.859 123.577 1.00 78.15  ? 34  VAL A C   1 
ATOM   234  O O   . VAL A 1 34  ? 114.579 122.745 122.813 1.00 86.04  ? 34  VAL A O   1 
ATOM   235  C CB  . VAL A 1 34  ? 114.355 122.871 125.796 1.00 63.54  ? 34  VAL A CB  1 
ATOM   236  C CG1 . VAL A 1 34  ? 114.686 121.401 125.932 1.00 76.41  ? 34  VAL A CG1 1 
ATOM   237  C CG2 . VAL A 1 34  ? 114.290 123.544 127.153 1.00 74.22  ? 34  VAL A CG2 1 
ATOM   238  N N   . LYS A 1 35  ? 116.750 122.375 123.295 1.00 73.86  ? 35  LYS A N   1 
ATOM   239  C CA  . LYS A 1 35  ? 117.053 121.685 122.048 1.00 70.67  ? 35  LYS A CA  1 
ATOM   240  C C   . LYS A 1 35  ? 116.903 120.186 122.274 1.00 72.99  ? 35  LYS A C   1 
ATOM   241  O O   . LYS A 1 35  ? 117.756 119.558 122.907 1.00 85.13  ? 35  LYS A O   1 
ATOM   242  C CB  . LYS A 1 35  ? 118.459 122.032 121.568 1.00 70.05  ? 35  LYS A CB  1 
ATOM   243  C CG  . LYS A 1 35  ? 118.815 123.498 121.721 1.00 75.17  ? 35  LYS A CG  1 
ATOM   244  C CD  . LYS A 1 35  ? 119.592 124.004 120.524 1.00 74.67  ? 35  LYS A CD  1 
ATOM   245  C CE  . LYS A 1 35  ? 121.062 123.652 120.638 1.00 78.09  ? 35  LYS A CE  1 
ATOM   246  N NZ  . LYS A 1 35  ? 121.714 123.557 119.304 1.00 80.55  ? 35  LYS A NZ  1 
ATOM   247  N N   . LEU A 1 36  ? 115.819 119.618 121.757 1.00 62.82  ? 36  LEU A N   1 
ATOM   248  C CA  . LEU A 1 36  ? 115.549 118.192 121.869 1.00 59.61  ? 36  LEU A CA  1 
ATOM   249  C C   . LEU A 1 36  ? 115.905 117.508 120.559 1.00 70.37  ? 36  LEU A C   1 
ATOM   250  O O   . LEU A 1 36  ? 115.387 117.880 119.501 1.00 79.78  ? 36  LEU A O   1 
ATOM   251  C CB  . LEU A 1 36  ? 114.080 117.940 122.205 1.00 58.00  ? 36  LEU A CB  1 
ATOM   252  C CG  . LEU A 1 36  ? 113.603 118.327 123.601 1.00 58.26  ? 36  LEU A CG  1 
ATOM   253  C CD1 . LEU A 1 36  ? 112.115 118.585 123.588 1.00 65.11  ? 36  LEU A CD1 1 
ATOM   254  C CD2 . LEU A 1 36  ? 113.939 117.229 124.582 1.00 66.85  ? 36  LEU A CD2 1 
ATOM   255  N N   . LEU A 1 37  ? 116.782 116.511 120.626 1.00 68.57  ? 37  LEU A N   1 
ATOM   256  C CA  . LEU A 1 37  ? 117.157 115.729 119.453 1.00 56.68  ? 37  LEU A CA  1 
ATOM   257  C C   . LEU A 1 37  ? 116.237 114.521 119.384 1.00 57.47  ? 37  LEU A C   1 
ATOM   258  O O   . LEU A 1 37  ? 116.288 113.645 120.249 1.00 69.23  ? 37  LEU A O   1 
ATOM   259  C CB  . LEU A 1 37  ? 118.620 115.299 119.515 1.00 60.41  ? 37  LEU A CB  1 
ATOM   260  C CG  . LEU A 1 37  ? 119.006 114.190 118.535 1.00 57.10  ? 37  LEU A CG  1 
ATOM   261  C CD1 . LEU A 1 37  ? 118.702 114.595 117.104 1.00 59.64  ? 37  LEU A CD1 1 
ATOM   262  C CD2 . LEU A 1 37  ? 120.467 113.817 118.686 1.00 65.31  ? 37  LEU A CD2 1 
ATOM   263  N N   . LEU A 1 38  ? 115.391 114.476 118.366 1.00 64.25  ? 38  LEU A N   1 
ATOM   264  C CA  . LEU A 1 38  ? 114.422 113.397 118.204 1.00 65.46  ? 38  LEU A CA  1 
ATOM   265  C C   . LEU A 1 38  ? 114.919 112.477 117.096 1.00 71.08  ? 38  LEU A C   1 
ATOM   266  O O   . LEU A 1 38  ? 115.054 112.892 115.943 1.00 77.52  ? 38  LEU A O   1 
ATOM   267  C CB  . LEU A 1 38  ? 113.037 113.965 117.913 1.00 63.48  ? 38  LEU A CB  1 
ATOM   268  C CG  . LEU A 1 38  ? 111.909 113.032 117.486 1.00 58.56  ? 38  LEU A CG  1 
ATOM   269  C CD1 . LEU A 1 38  ? 110.591 113.560 117.995 1.00 69.05  ? 38  LEU A CD1 1 
ATOM   270  C CD2 . LEU A 1 38  ? 111.861 112.961 115.982 1.00 63.98  ? 38  LEU A CD2 1 
ATOM   271  N N   . LEU A 1 39  ? 115.207 111.228 117.453 1.00 67.52  ? 39  LEU A N   1 
ATOM   272  C CA  . LEU A 1 39  ? 115.594 110.215 116.486 1.00 64.23  ? 39  LEU A CA  1 
ATOM   273  C C   . LEU A 1 39  ? 115.047 108.864 116.915 1.00 61.72  ? 39  LEU A C   1 
ATOM   274  O O   . LEU A 1 39  ? 114.745 108.640 118.089 1.00 67.83  ? 39  LEU A O   1 
ATOM   275  C CB  . LEU A 1 39  ? 117.117 110.145 116.309 1.00 64.02  ? 39  LEU A CB  1 
ATOM   276  C CG  . LEU A 1 39  ? 118.079 110.261 117.492 1.00 67.99  ? 39  LEU A CG  1 
ATOM   277  C CD1 . LEU A 1 39  ? 117.855 109.183 118.531 1.00 64.63  ? 39  LEU A CD1 1 
ATOM   278  C CD2 . LEU A 1 39  ? 119.507 110.232 116.990 1.00 72.49  ? 39  LEU A CD2 1 
ATOM   279  N N   . GLY A 1 40  ? 114.916 107.968 115.947 1.00 78.33  ? 40  GLY A N   1 
ATOM   280  C CA  . GLY A 1 40  ? 114.404 106.640 116.223 1.00 79.28  ? 40  GLY A CA  1 
ATOM   281  C C   . GLY A 1 40  ? 114.260 105.869 114.934 1.00 88.06  ? 40  GLY A C   1 
ATOM   282  O O   . GLY A 1 40  ? 114.598 106.353 113.849 1.00 88.63  ? 40  GLY A O   1 
ATOM   283  N N   . ALA A 1 41  ? 113.753 104.648 115.068 1.00 95.46  ? 41  ALA A N   1 
ATOM   284  C CA  . ALA A 1 41  ? 113.497 103.824 113.899 1.00 90.35  ? 41  ALA A CA  1 
ATOM   285  C C   . ALA A 1 41  ? 112.369 104.422 113.068 1.00 95.91  ? 41  ALA A C   1 
ATOM   286  O O   . ALA A 1 41  ? 111.537 105.185 113.564 1.00 96.08  ? 41  ALA A O   1 
ATOM   287  C CB  . ALA A 1 41  ? 113.144 102.397 114.317 1.00 87.57  ? 41  ALA A CB  1 
ATOM   288  N N   . GLY A 1 42  ? 112.357 104.078 111.783 1.00 106.79 ? 42  GLY A N   1 
ATOM   289  C CA  . GLY A 1 42  ? 111.305 104.557 110.909 1.00 99.70  ? 42  GLY A CA  1 
ATOM   290  C C   . GLY A 1 42  ? 109.954 103.982 111.287 1.00 102.56 ? 42  GLY A C   1 
ATOM   291  O O   . GLY A 1 42  ? 109.853 102.908 111.878 1.00 106.39 ? 42  GLY A O   1 
ATOM   292  N N   . GLU A 1 43  ? 108.904 104.746 110.971 1.00 108.04 ? 43  GLU A N   1 
ATOM   293  C CA  . GLU A 1 43  ? 107.502 104.367 111.212 1.00 111.48 ? 43  GLU A CA  1 
ATOM   294  C C   . GLU A 1 43  ? 107.266 103.868 112.638 1.00 112.24 ? 43  GLU A C   1 
ATOM   295  O O   . GLU A 1 43  ? 106.256 103.232 112.940 1.00 112.39 ? 43  GLU A O   1 
ATOM   296  C CB  . GLU A 1 43  ? 106.994 103.386 110.132 1.00 109.19 ? 43  GLU A CB  1 
ATOM   297  C CG  . GLU A 1 43  ? 107.694 102.020 109.858 1.00 110.24 ? 43  GLU A CG  1 
ATOM   298  C CD  . GLU A 1 43  ? 107.851 101.053 111.026 1.00 114.13 ? 43  GLU A CD  1 
ATOM   299  O OE1 . GLU A 1 43  ? 108.719 100.164 110.921 1.00 116.87 ? 43  GLU A OE1 1 
ATOM   300  O OE2 . GLU A 1 43  ? 107.076 101.095 111.994 1.00 112.96 ? 43  GLU A OE2 1 
ATOM   301  N N   . SER A 1 44  ? 108.148 104.270 113.548 1.00 102.89 ? 44  SER A N   1 
ATOM   302  C CA  . SER A 1 44  ? 108.109 103.855 114.942 1.00 101.29 ? 44  SER A CA  1 
ATOM   303  C C   . SER A 1 44  ? 107.373 104.885 115.784 1.00 98.84  ? 44  SER A C   1 
ATOM   304  O O   . SER A 1 44  ? 107.697 105.115 116.950 1.00 99.84  ? 44  SER A O   1 
ATOM   305  C CB  . SER A 1 44  ? 109.518 103.628 115.481 1.00 103.13 ? 44  SER A CB  1 
ATOM   306  O OG  . SER A 1 44  ? 110.242 104.845 115.529 1.00 103.11 ? 44  SER A OG  1 
ATOM   307  N N   . GLY A 1 45  ? 106.370 105.525 115.190 1.00 97.70  ? 45  GLY A N   1 
ATOM   308  C CA  . GLY A 1 45  ? 105.619 106.541 115.894 1.00 99.82  ? 45  GLY A CA  1 
ATOM   309  C C   . GLY A 1 45  ? 106.297 107.887 115.961 1.00 104.48 ? 45  GLY A C   1 
ATOM   310  O O   . GLY A 1 45  ? 105.858 108.755 116.717 1.00 107.83 ? 45  GLY A O   1 
ATOM   311  N N   . LYS A 1 46  ? 107.370 108.081 115.195 1.00 92.94  ? 46  LYS A N   1 
ATOM   312  C CA  . LYS A 1 46  ? 108.032 109.379 115.150 1.00 89.15  ? 46  LYS A CA  1 
ATOM   313  C C   . LYS A 1 46  ? 107.094 110.454 114.614 1.00 96.15  ? 46  LYS A C   1 
ATOM   314  O O   . LYS A 1 46  ? 106.961 111.538 115.201 1.00 97.44  ? 46  LYS A O   1 
ATOM   315  C CB  . LYS A 1 46  ? 109.283 109.271 114.281 1.00 84.53  ? 46  LYS A CB  1 
ATOM   316  C CG  . LYS A 1 46  ? 110.136 110.509 114.248 1.00 86.39  ? 46  LYS A CG  1 
ATOM   317  C CD  . LYS A 1 46  ? 111.249 110.378 113.221 1.00 91.10  ? 46  LYS A CD  1 
ATOM   318  C CE  . LYS A 1 46  ? 112.073 109.124 113.445 1.00 92.67  ? 46  LYS A CE  1 
ATOM   319  N NZ  . LYS A 1 46  ? 112.400 108.926 114.882 1.00 95.89  ? 46  LYS A NZ  1 
ATOM   320  N N   . ASN A 1 47  ? 106.420 110.158 113.499 1.00 111.84 ? 47  ASN A N   1 
ATOM   321  C CA  . ASN A 1 47  ? 105.542 111.136 112.869 1.00 108.19 ? 47  ASN A CA  1 
ATOM   322  C C   . ASN A 1 47  ? 104.389 111.515 113.787 1.00 110.05 ? 47  ASN A C   1 
ATOM   323  O O   . ASN A 1 47  ? 104.088 112.699 113.967 1.00 110.57 ? 47  ASN A O   1 
ATOM   324  C CB  . ASN A 1 47  ? 105.022 110.589 111.539 1.00 108.23 ? 47  ASN A CB  1 
ATOM   325  C CG  . ASN A 1 47  ? 104.482 109.176 111.661 1.00 111.65 ? 47  ASN A CG  1 
ATOM   326  O OD1 . ASN A 1 47  ? 104.357 108.639 112.761 1.00 112.02 ? 47  ASN A OD1 1 
ATOM   327  N ND2 . ASN A 1 47  ? 104.156 108.568 110.527 1.00 110.57 ? 47  ASN A ND2 1 
ATOM   328  N N   . THR A 1 48  ? 103.737 110.523 114.396 1.00 109.53 ? 48  THR A N   1 
ATOM   329  C CA  . THR A 1 48  ? 102.629 110.848 115.287 1.00 108.21 ? 48  THR A CA  1 
ATOM   330  C C   . THR A 1 48  ? 103.111 111.571 116.537 1.00 106.15 ? 48  THR A C   1 
ATOM   331  O O   . THR A 1 48  ? 102.397 112.441 117.050 1.00 109.83 ? 48  THR A O   1 
ATOM   332  C CB  . THR A 1 48  ? 101.840 109.592 115.664 1.00 106.34 ? 48  THR A CB  1 
ATOM   333  O OG1 . THR A 1 48  ? 100.797 109.944 116.582 1.00 104.42 ? 48  THR A OG1 1 
ATOM   334  C CG2 . THR A 1 48  ? 102.735 108.556 116.306 1.00 104.93 ? 48  THR A CG2 1 
ATOM   335  N N   . ILE A 1 49  ? 104.310 111.240 117.030 1.00 100.69 ? 49  ILE A N   1 
ATOM   336  C CA  . ILE A 1 49  ? 104.845 111.927 118.203 1.00 103.61 ? 49  ILE A CA  1 
ATOM   337  C C   . ILE A 1 49  ? 105.028 113.408 117.909 1.00 103.65 ? 49  ILE A C   1 
ATOM   338  O O   . ILE A 1 49  ? 104.499 114.271 118.627 1.00 105.17 ? 49  ILE A O   1 
ATOM   339  C CB  . ILE A 1 49  ? 106.160 111.277 118.669 1.00 101.53 ? 49  ILE A CB  1 
ATOM   340  C CG1 . ILE A 1 49  ? 105.867 110.109 119.609 1.00 101.79 ? 49  ILE A CG1 1 
ATOM   341  C CG2 . ILE A 1 49  ? 107.051 112.296 119.368 1.00 98.45  ? 49  ILE A CG2 1 
ATOM   342  C CD1 . ILE A 1 49  ? 105.596 110.523 121.039 1.00 102.95 ? 49  ILE A CD1 1 
ATOM   343  N N   . VAL A 1 50  ? 105.754 113.723 116.830 1.00 103.14 ? 50  VAL A N   1 
ATOM   344  C CA  . VAL A 1 50  ? 105.941 115.122 116.478 1.00 102.43 ? 50  VAL A CA  1 
ATOM   345  C C   . VAL A 1 50  ? 104.605 115.773 116.166 1.00 107.42 ? 50  VAL A C   1 
ATOM   346  O O   . VAL A 1 50  ? 104.428 116.971 116.419 1.00 111.11 ? 50  VAL A O   1 
ATOM   347  C CB  . VAL A 1 50  ? 106.938 115.275 115.310 1.00 103.55 ? 50  VAL A CB  1 
ATOM   348  C CG1 . VAL A 1 50  ? 106.369 114.722 114.022 1.00 104.36 ? 50  VAL A CG1 1 
ATOM   349  C CG2 . VAL A 1 50  ? 107.319 116.732 115.125 1.00 105.26 ? 50  VAL A CG2 1 
ATOM   350  N N   . LYS A 1 51  ? 103.633 114.998 115.678 1.00 116.72 ? 51  LYS A N   1 
ATOM   351  C CA  . LYS A 1 51  ? 102.324 115.562 115.383 1.00 116.76 ? 51  LYS A CA  1 
ATOM   352  C C   . LYS A 1 51  ? 101.618 116.037 116.647 1.00 117.87 ? 51  LYS A C   1 
ATOM   353  O O   . LYS A 1 51  ? 101.193 117.196 116.721 1.00 117.78 ? 51  LYS A O   1 
ATOM   354  C CB  . LYS A 1 51  ? 101.462 114.544 114.640 1.00 113.50 ? 51  LYS A CB  1 
ATOM   355  C CG  . LYS A 1 51  ? 99.982  114.890 114.645 1.00 113.78 ? 51  LYS A CG  1 
ATOM   356  C CD  . LYS A 1 51  ? 99.150  113.757 114.079 1.00 115.37 ? 51  LYS A CD  1 
ATOM   357  C CE  . LYS A 1 51  ? 99.627  113.383 112.687 1.00 117.09 ? 51  LYS A CE  1 
ATOM   358  N NZ  . LYS A 1 51  ? 99.553  114.543 111.755 1.00 117.22 ? 51  LYS A NZ  1 
ATOM   359  N N   . GLN A 1 52  ? 101.478 115.173 117.663 1.00 115.88 ? 52  GLN A N   1 
ATOM   360  C CA  . GLN A 1 52  ? 100.611 115.619 118.752 1.00 115.26 ? 52  GLN A CA  1 
ATOM   361  C C   . GLN A 1 52  ? 101.377 116.526 119.701 1.00 112.57 ? 52  GLN A C   1 
ATOM   362  O O   . GLN A 1 52  ? 100.765 117.273 120.473 1.00 115.12 ? 52  GLN A O   1 
ATOM   363  C CB  . GLN A 1 52  ? 99.960  114.487 119.565 1.00 113.34 ? 52  GLN A CB  1 
ATOM   364  C CG  . GLN A 1 52  ? 100.840 113.525 120.380 1.00 111.12 ? 52  GLN A CG  1 
ATOM   365  C CD  . GLN A 1 52  ? 100.130 112.459 121.137 1.00 114.31 ? 52  GLN A CD  1 
ATOM   366  O OE1 . GLN A 1 52  ? 99.001  112.143 120.829 1.00 115.21 ? 52  GLN A OE1 1 
ATOM   367  N NE2 . GLN A 1 52  ? 100.780 111.909 122.154 1.00 113.93 ? 52  GLN A NE2 1 
ATOM   368  N N   . MET A 1 53  ? 102.713 116.488 119.671 1.00 107.85 ? 53  MET A N   1 
ATOM   369  C CA  . MET A 1 53  ? 103.402 117.459 120.512 1.00 110.90 ? 53  MET A CA  1 
ATOM   370  C C   . MET A 1 53  ? 103.796 118.713 119.744 1.00 113.39 ? 53  MET A C   1 
ATOM   371  O O   . MET A 1 53  ? 104.444 119.597 120.316 1.00 116.04 ? 53  MET A O   1 
ATOM   372  C CB  . MET A 1 53  ? 104.610 116.819 121.200 1.00 113.84 ? 53  MET A CB  1 
ATOM   373  C CG  . MET A 1 53  ? 105.749 116.419 120.315 1.00 115.66 ? 53  MET A CG  1 
ATOM   374  S SD  . MET A 1 53  ? 107.249 116.380 121.300 1.00 124.00 ? 53  MET A SD  1 
ATOM   375  C CE  . MET A 1 53  ? 106.861 115.027 122.403 1.00 111.59 ? 53  MET A CE  1 
ATOM   376  N N   . LYS A 1 54  ? 103.426 118.805 118.463 1.00 121.08 ? 54  LYS A N   1 
ATOM   377  C CA  . LYS A 1 54  ? 103.265 120.111 117.834 1.00 122.11 ? 54  LYS A CA  1 
ATOM   378  C C   . LYS A 1 54  ? 102.040 120.827 118.386 1.00 122.55 ? 54  LYS A C   1 
ATOM   379  O O   . LYS A 1 54  ? 101.956 122.059 118.317 1.00 121.18 ? 54  LYS A O   1 
ATOM   380  C CB  . LYS A 1 54  ? 103.143 119.951 116.316 1.00 117.91 ? 54  LYS A CB  1 
ATOM   381  C CG  . LYS A 1 54  ? 104.011 120.890 115.483 1.00 116.58 ? 54  LYS A CG  1 
ATOM   382  C CD  . LYS A 1 54  ? 103.819 122.348 115.867 1.00 119.15 ? 54  LYS A CD  1 
ATOM   383  C CE  . LYS A 1 54  ? 104.447 123.286 114.847 1.00 119.87 ? 54  LYS A CE  1 
ATOM   384  N NZ  . LYS A 1 54  ? 104.295 124.716 115.239 1.00 119.46 ? 54  LYS A NZ  1 
ATOM   385  N N   . ILE A 1 55  ? 101.096 120.071 118.953 1.00 129.17 ? 55  ILE A N   1 
ATOM   386  C CA  . ILE A 1 55  ? 99.828  120.584 119.462 1.00 128.55 ? 55  ILE A CA  1 
ATOM   387  C C   . ILE A 1 55  ? 99.115  121.350 118.356 1.00 131.31 ? 55  ILE A C   1 
ATOM   388  O O   . ILE A 1 55  ? 98.741  122.516 118.532 1.00 130.04 ? 55  ILE A O   1 
ATOM   389  C CB  . ILE A 1 55  ? 100.026 121.459 120.716 1.00 127.45 ? 55  ILE A CB  1 
ATOM   390  C CG1 . ILE A 1 55  ? 101.155 120.905 121.586 1.00 129.13 ? 55  ILE A CG1 1 
ATOM   391  C CG2 . ILE A 1 55  ? 98.741  121.522 121.528 1.00 125.82 ? 55  ILE A CG2 1 
ATOM   392  C CD1 . ILE A 1 55  ? 101.466 121.756 122.798 1.00 128.23 ? 55  ILE A CD1 1 
ATOM   393  N N   . ILE A 1 56  ? 98.932  120.695 117.211 1.00 139.79 ? 56  ILE A N   1 
ATOM   394  C CA  . ILE A 1 56  ? 98.246  121.273 116.057 1.00 139.38 ? 56  ILE A CA  1 
ATOM   395  C C   . ILE A 1 56  ? 98.872  122.602 115.646 1.00 136.69 ? 56  ILE A C   1 
ATOM   396  O O   . ILE A 1 56  ? 99.996  122.641 115.145 1.00 135.16 ? 56  ILE A O   1 
ATOM   397  C CB  . ILE A 1 56  ? 96.739  121.443 116.334 1.00 138.18 ? 56  ILE A CB  1 
ATOM   398  C CG1 . ILE A 1 56  ? 96.051  120.077 116.410 1.00 136.37 ? 56  ILE A CG1 1 
ATOM   399  C CG2 . ILE A 1 56  ? 96.094  122.310 115.264 1.00 135.31 ? 56  ILE A CG2 1 
ATOM   400  C CD1 . ILE A 1 56  ? 95.851  119.567 117.821 1.00 133.85 ? 56  ILE A CD1 1 
ATOM   401  N N   . THR A 1 183 ? 114.149 117.649 101.964 1.00 81.81  ? 183 THR A N   1 
ATOM   402  C CA  . THR A 1 183 ? 114.494 116.770 103.075 1.00 85.66  ? 183 THR A CA  1 
ATOM   403  C C   . THR A 1 183 ? 115.296 117.517 104.133 1.00 90.39  ? 183 THR A C   1 
ATOM   404  O O   . THR A 1 183 ? 115.030 118.684 104.416 1.00 93.04  ? 183 THR A O   1 
ATOM   405  C CB  . THR A 1 183 ? 115.301 115.553 102.601 1.00 88.47  ? 183 THR A CB  1 
ATOM   406  O OG1 . THR A 1 183 ? 116.578 115.986 102.115 1.00 91.45  ? 183 THR A OG1 1 
ATOM   407  C CG2 . THR A 1 183 ? 114.563 114.827 101.491 1.00 87.59  ? 183 THR A CG2 1 
ATOM   408  N N   . GLY A 1 184 ? 116.281 116.837 104.713 1.00 85.39  ? 184 GLY A N   1 
ATOM   409  C CA  . GLY A 1 184 ? 117.105 117.432 105.744 1.00 84.13  ? 184 GLY A CA  1 
ATOM   410  C C   . GLY A 1 184 ? 116.463 117.382 107.111 1.00 84.51  ? 184 GLY A C   1 
ATOM   411  O O   . GLY A 1 184 ? 115.421 116.760 107.338 1.00 86.03  ? 184 GLY A O   1 
ATOM   412  N N   . ILE A 1 185 ? 117.119 118.060 108.054 1.00 71.82  ? 185 ILE A N   1 
ATOM   413  C CA  . ILE A 1 185 ? 116.603 118.127 109.413 1.00 66.77  ? 185 ILE A CA  1 
ATOM   414  C C   . ILE A 1 185 ? 115.285 118.879 109.419 1.00 65.81  ? 185 ILE A C   1 
ATOM   415  O O   . ILE A 1 185 ? 115.150 119.940 108.796 1.00 69.32  ? 185 ILE A O   1 
ATOM   416  C CB  . ILE A 1 185 ? 117.624 118.794 110.343 1.00 70.28  ? 185 ILE A CB  1 
ATOM   417  C CG1 . ILE A 1 185 ? 118.958 118.054 110.285 1.00 73.03  ? 185 ILE A CG1 1 
ATOM   418  C CG2 . ILE A 1 185 ? 117.091 118.847 111.766 1.00 76.66  ? 185 ILE A CG2 1 
ATOM   419  C CD1 . ILE A 1 185 ? 119.820 118.262 111.506 1.00 73.90  ? 185 ILE A CD1 1 
ATOM   420  N N   . VAL A 1 186 ? 114.302 118.332 110.122 1.00 70.90  ? 186 VAL A N   1 
ATOM   421  C CA  . VAL A 1 186 ? 113.020 118.991 110.322 1.00 71.89  ? 186 VAL A CA  1 
ATOM   422  C C   . VAL A 1 186 ? 113.039 119.625 111.703 1.00 73.76  ? 186 VAL A C   1 
ATOM   423  O O   . VAL A 1 186 ? 113.207 118.930 112.712 1.00 82.54  ? 186 VAL A O   1 
ATOM   424  C CB  . VAL A 1 186 ? 111.851 118.006 110.177 1.00 75.46  ? 186 VAL A CB  1 
ATOM   425  C CG1 . VAL A 1 186 ? 110.529 118.728 110.353 1.00 76.21  ? 186 VAL A CG1 1 
ATOM   426  C CG2 . VAL A 1 186 ? 111.912 117.316 108.828 1.00 70.54  ? 186 VAL A CG2 1 
ATOM   427  N N   . GLU A 1 187 ? 112.885 120.942 111.754 1.00 73.32  ? 187 GLU A N   1 
ATOM   428  C CA  . GLU A 1 187 ? 112.897 121.680 113.007 1.00 73.00  ? 187 GLU A CA  1 
ATOM   429  C C   . GLU A 1 187 ? 111.465 122.025 113.389 1.00 78.63  ? 187 GLU A C   1 
ATOM   430  O O   . GLU A 1 187 ? 110.745 122.661 112.612 1.00 88.02  ? 187 GLU A O   1 
ATOM   431  C CB  . GLU A 1 187 ? 113.744 122.946 112.893 1.00 79.00  ? 187 GLU A CB  1 
ATOM   432  C CG  . GLU A 1 187 ? 115.123 122.713 112.309 1.00 84.59  ? 187 GLU A CG  1 
ATOM   433  C CD  . GLU A 1 187 ? 116.119 123.771 112.736 1.00 90.65  ? 187 GLU A CD  1 
ATOM   434  O OE1 . GLU A 1 187 ? 115.943 124.347 113.830 1.00 91.05  ? 187 GLU A OE1 1 
ATOM   435  O OE2 . GLU A 1 187 ? 117.079 124.027 111.979 1.00 90.01  ? 187 GLU A OE2 1 
ATOM   436  N N   . THR A 1 188 ? 111.061 121.601 114.578 1.00 62.84  ? 188 THR A N   1 
ATOM   437  C CA  . THR A 1 188 ? 109.731 121.861 115.105 1.00 63.06  ? 188 THR A CA  1 
ATOM   438  C C   . THR A 1 188 ? 109.848 122.731 116.347 1.00 69.90  ? 188 THR A C   1 
ATOM   439  O O   . THR A 1 188 ? 110.557 122.377 117.292 1.00 75.96  ? 188 THR A O   1 
ATOM   440  C CB  . THR A 1 188 ? 109.014 120.554 115.440 1.00 64.24  ? 188 THR A CB  1 
ATOM   441  O OG1 . THR A 1 188 ? 109.185 119.628 114.362 1.00 67.58  ? 188 THR A OG1 1 
ATOM   442  C CG2 . THR A 1 188 ? 107.540 120.804 115.650 1.00 67.17  ? 188 THR A CG2 1 
ATOM   443  N N   . HIS A 1 189 ? 109.158 123.862 116.344 1.00 78.82  ? 189 HIS A N   1 
ATOM   444  C CA  . HIS A 1 189 ? 109.188 124.802 117.453 1.00 74.91  ? 189 HIS A CA  1 
ATOM   445  C C   . HIS A 1 189 ? 107.875 124.709 118.209 1.00 80.99  ? 189 HIS A C   1 
ATOM   446  O O   . HIS A 1 189 ? 106.803 124.824 117.606 1.00 88.15  ? 189 HIS A O   1 
ATOM   447  C CB  . HIS A 1 189 ? 109.402 126.228 116.949 1.00 80.95  ? 189 HIS A CB  1 
ATOM   448  C CG  . HIS A 1 189 ? 110.742 126.456 116.328 1.00 85.54  ? 189 HIS A CG  1 
ATOM   449  N ND1 . HIS A 1 189 ? 111.113 125.882 115.132 1.00 85.86  ? 189 HIS A ND1 1 
ATOM   450  C CD2 . HIS A 1 189 ? 111.791 127.213 116.723 1.00 84.21  ? 189 HIS A CD2 1 
ATOM   451  C CE1 . HIS A 1 189 ? 112.340 126.264 114.825 1.00 84.97  ? 189 HIS A CE1 1 
ATOM   452  N NE2 . HIS A 1 189 ? 112.773 127.074 115.773 1.00 85.23  ? 189 HIS A NE2 1 
ATOM   453  N N   . PHE A 1 190 ? 107.950 124.497 119.520 1.00 82.02  ? 190 PHE A N   1 
ATOM   454  C CA  . PHE A 1 190 ? 106.722 124.516 120.302 1.00 81.95  ? 190 PHE A CA  1 
ATOM   455  C C   . PHE A 1 190 ? 107.007 125.004 121.713 1.00 89.37  ? 190 PHE A C   1 
ATOM   456  O O   . PHE A 1 190 ? 108.072 124.748 122.275 1.00 95.49  ? 190 PHE A O   1 
ATOM   457  C CB  . PHE A 1 190 ? 106.032 123.144 120.317 1.00 75.78  ? 190 PHE A CB  1 
ATOM   458  C CG  . PHE A 1 190 ? 106.789 122.077 121.050 1.00 78.65  ? 190 PHE A CG  1 
ATOM   459  C CD1 . PHE A 1 190 ? 107.786 121.359 120.417 1.00 83.25  ? 190 PHE A CD1 1 
ATOM   460  C CD2 . PHE A 1 190 ? 106.481 121.766 122.361 1.00 86.79  ? 190 PHE A CD2 1 
ATOM   461  C CE1 . PHE A 1 190 ? 108.473 120.366 121.084 1.00 84.31  ? 190 PHE A CE1 1 
ATOM   462  C CE2 . PHE A 1 190 ? 107.166 120.776 123.032 1.00 86.73  ? 190 PHE A CE2 1 
ATOM   463  C CZ  . PHE A 1 190 ? 108.161 120.074 122.392 1.00 83.80  ? 190 PHE A CZ  1 
ATOM   464  N N   . THR A 1 191 ? 106.038 125.714 122.279 1.00 90.46  ? 191 THR A N   1 
ATOM   465  C CA  . THR A 1 191 ? 106.172 126.318 123.596 1.00 85.11  ? 191 THR A CA  1 
ATOM   466  C C   . THR A 1 191 ? 105.198 125.655 124.556 1.00 86.23  ? 191 THR A C   1 
ATOM   467  O O   . THR A 1 191 ? 104.010 125.519 124.247 1.00 87.48  ? 191 THR A O   1 
ATOM   468  C CB  . THR A 1 191 ? 105.907 127.822 123.537 1.00 87.54  ? 191 THR A CB  1 
ATOM   469  O OG1 . THR A 1 191 ? 104.533 128.051 123.204 1.00 93.04  ? 191 THR A OG1 1 
ATOM   470  C CG2 . THR A 1 191 ? 106.782 128.467 122.479 1.00 86.63  ? 191 THR A CG2 1 
ATOM   471  N N   . PHE A 1 192 ? 105.703 125.241 125.715 1.00 84.13  ? 192 PHE A N   1 
ATOM   472  C CA  . PHE A 1 192 ? 104.868 124.655 126.755 1.00 84.41  ? 192 PHE A CA  1 
ATOM   473  C C   . PHE A 1 192 ? 105.259 125.260 128.092 1.00 88.32  ? 192 PHE A C   1 
ATOM   474  O O   . PHE A 1 192 ? 106.401 125.102 128.533 1.00 90.52  ? 192 PHE A O   1 
ATOM   475  C CB  . PHE A 1 192 ? 105.012 123.133 126.795 1.00 77.83  ? 192 PHE A CB  1 
ATOM   476  C CG  . PHE A 1 192 ? 103.903 122.447 127.530 1.00 80.58  ? 192 PHE A CG  1 
ATOM   477  C CD1 . PHE A 1 192 ? 102.617 122.450 127.024 1.00 83.49  ? 192 PHE A CD1 1 
ATOM   478  C CD2 . PHE A 1 192 ? 104.144 121.806 128.730 1.00 84.99  ? 192 PHE A CD2 1 
ATOM   479  C CE1 . PHE A 1 192 ? 101.593 121.820 127.699 1.00 84.09  ? 192 PHE A CE1 1 
ATOM   480  C CE2 . PHE A 1 192 ? 103.123 121.176 129.410 1.00 85.58  ? 192 PHE A CE2 1 
ATOM   481  C CZ  . PHE A 1 192 ? 101.846 121.183 128.893 1.00 82.90  ? 192 PHE A CZ  1 
ATOM   482  N N   . LYS A 1 193 ? 104.311 125.945 128.728 1.00 86.33  ? 193 LYS A N   1 
ATOM   483  C CA  . LYS A 1 193 ? 104.501 126.551 130.043 1.00 82.93  ? 193 LYS A CA  1 
ATOM   484  C C   . LYS A 1 193 ? 105.732 127.456 130.062 1.00 84.96  ? 193 LYS A C   1 
ATOM   485  O O   . LYS A 1 193 ? 106.656 127.288 130.860 1.00 84.07  ? 193 LYS A O   1 
ATOM   486  C CB  . LYS A 1 193 ? 104.586 125.477 131.128 1.00 86.03  ? 193 LYS A CB  1 
ATOM   487  C CG  . LYS A 1 193 ? 103.340 124.617 131.236 1.00 87.48  ? 193 LYS A CG  1 
ATOM   488  C CD  . LYS A 1 193 ? 103.366 123.760 132.489 1.00 90.67  ? 193 LYS A CD  1 
ATOM   489  C CE  . LYS A 1 193 ? 102.107 122.918 132.605 1.00 88.79  ? 193 LYS A CE  1 
ATOM   490  N NZ  . LYS A 1 193 ? 100.876 123.744 132.470 1.00 88.55  ? 193 LYS A NZ  1 
ATOM   491  N N   . ASP A 1 194 ? 105.724 128.430 129.152 1.00 94.50  ? 194 ASP A N   1 
ATOM   492  C CA  . ASP A 1 194 ? 106.775 129.445 129.064 1.00 93.10  ? 194 ASP A CA  1 
ATOM   493  C C   . ASP A 1 194 ? 108.154 128.811 128.900 1.00 87.91  ? 194 ASP A C   1 
ATOM   494  O O   . ASP A 1 194 ? 109.136 129.251 129.500 1.00 90.78  ? 194 ASP A O   1 
ATOM   495  C CB  . ASP A 1 194 ? 106.747 130.374 130.279 1.00 98.41  ? 194 ASP A CB  1 
ATOM   496  C CG  . ASP A 1 194 ? 105.363 130.928 130.557 1.00 101.63 ? 194 ASP A CG  1 
ATOM   497  O OD1 . ASP A 1 194 ? 104.424 130.587 129.807 1.00 102.82 ? 194 ASP A OD1 1 
ATOM   498  O OD2 . ASP A 1 194 ? 105.215 131.704 131.524 1.00 98.67  ? 194 ASP A OD2 1 
ATOM   499  N N   . LEU A 1 195 ? 108.228 127.765 128.083 1.00 65.21  ? 195 LEU A N   1 
ATOM   500  C CA  . LEU A 1 195 ? 109.494 127.122 127.763 1.00 64.32  ? 195 LEU A CA  1 
ATOM   501  C C   . LEU A 1 195 ? 109.523 126.815 126.276 1.00 72.58  ? 195 LEU A C   1 
ATOM   502  O O   . LEU A 1 195 ? 108.644 126.112 125.770 1.00 75.33  ? 195 LEU A O   1 
ATOM   503  C CB  . LEU A 1 195 ? 109.690 125.840 128.579 1.00 68.76  ? 195 LEU A CB  1 
ATOM   504  C CG  . LEU A 1 195 ? 111.131 125.392 128.820 1.00 67.63  ? 195 LEU A CG  1 
ATOM   505  C CD1 . LEU A 1 195 ? 112.020 126.583 129.121 1.00 67.21  ? 195 LEU A CD1 1 
ATOM   506  C CD2 . LEU A 1 195 ? 111.189 124.383 129.951 1.00 71.23  ? 195 LEU A CD2 1 
ATOM   507  N N   . HIS A 1 196 ? 110.525 127.344 125.582 1.00 79.87  ? 196 HIS A N   1 
ATOM   508  C CA  . HIS A 1 196 ? 110.673 127.123 124.152 1.00 79.06  ? 196 HIS A CA  1 
ATOM   509  C C   . HIS A 1 196 ? 111.352 125.785 123.903 1.00 86.64  ? 196 HIS A C   1 
ATOM   510  O O   . HIS A 1 196 ? 112.324 125.434 124.577 1.00 93.84  ? 196 HIS A O   1 
ATOM   511  C CB  . HIS A 1 196 ? 111.485 128.250 123.514 1.00 79.07  ? 196 HIS A CB  1 
ATOM   512  C CG  . HIS A 1 196 ? 110.834 129.593 123.614 1.00 86.42  ? 196 HIS A CG  1 
ATOM   513  N ND1 . HIS A 1 196 ? 109.472 129.752 123.748 1.00 85.06  ? 196 HIS A ND1 1 
ATOM   514  C CD2 . HIS A 1 196 ? 111.358 130.841 123.602 1.00 88.52  ? 196 HIS A CD2 1 
ATOM   515  C CE1 . HIS A 1 196 ? 109.184 131.039 123.813 1.00 87.59  ? 196 HIS A CE1 1 
ATOM   516  N NE2 . HIS A 1 196 ? 110.311 131.722 123.727 1.00 87.69  ? 196 HIS A NE2 1 
ATOM   517  N N   . PHE A 1 197 ? 110.842 125.041 122.924 1.00 79.30  ? 197 PHE A N   1 
ATOM   518  C CA  . PHE A 1 197 ? 111.339 123.710 122.611 1.00 72.08  ? 197 PHE A CA  1 
ATOM   519  C C   . PHE A 1 197 ? 111.651 123.638 121.128 1.00 75.66  ? 197 PHE A C   1 
ATOM   520  O O   . PHE A 1 197 ? 110.771 123.884 120.293 1.00 84.63  ? 197 PHE A O   1 
ATOM   521  C CB  . PHE A 1 197 ? 110.315 122.635 122.975 1.00 69.64  ? 197 PHE A CB  1 
ATOM   522  C CG  . PHE A 1 197 ? 110.190 122.381 124.443 1.00 71.43  ? 197 PHE A CG  1 
ATOM   523  C CD1 . PHE A 1 197 ? 111.135 121.628 125.107 1.00 72.86  ? 197 PHE A CD1 1 
ATOM   524  C CD2 . PHE A 1 197 ? 109.112 122.871 125.153 1.00 79.34  ? 197 PHE A CD2 1 
ATOM   525  C CE1 . PHE A 1 197 ? 111.019 121.383 126.454 1.00 77.23  ? 197 PHE A CE1 1 
ATOM   526  C CE2 . PHE A 1 197 ? 108.990 122.629 126.503 1.00 82.04  ? 197 PHE A CE2 1 
ATOM   527  C CZ  . PHE A 1 197 ? 109.946 121.883 127.154 1.00 77.63  ? 197 PHE A CZ  1 
ATOM   528  N N   . LYS A 1 198 ? 112.894 123.288 120.815 1.00 71.97  ? 198 LYS A N   1 
ATOM   529  C CA  . LYS A 1 198 ? 113.328 122.989 119.460 1.00 71.00  ? 198 LYS A CA  1 
ATOM   530  C C   . LYS A 1 198 ? 113.456 121.478 119.323 1.00 74.58  ? 198 LYS A C   1 
ATOM   531  O O   . LYS A 1 198 ? 114.149 120.838 120.120 1.00 86.64  ? 198 LYS A O   1 
ATOM   532  C CB  . LYS A 1 198 ? 114.665 123.660 119.153 1.00 72.52  ? 198 LYS A CB  1 
ATOM   533  C CG  . LYS A 1 198 ? 114.781 125.092 119.626 1.00 75.07  ? 198 LYS A CG  1 
ATOM   534  C CD  . LYS A 1 198 ? 114.371 126.056 118.537 1.00 79.85  ? 198 LYS A CD  1 
ATOM   535  C CE  . LYS A 1 198 ? 115.395 126.086 117.415 1.00 78.20  ? 198 LYS A CE  1 
ATOM   536  N NZ  . LYS A 1 198 ? 116.603 126.878 117.770 1.00 79.53  ? 198 LYS A NZ  1 
ATOM   537  N N   . MET A 1 199 ? 112.792 120.914 118.322 1.00 71.71  ? 199 MET A N   1 
ATOM   538  C CA  . MET A 1 199 ? 112.842 119.488 118.039 1.00 67.95  ? 199 MET A CA  1 
ATOM   539  C C   . MET A 1 199 ? 113.498 119.275 116.686 1.00 75.74  ? 199 MET A C   1 
ATOM   540  O O   . MET A 1 199 ? 113.120 119.918 115.702 1.00 87.94  ? 199 MET A O   1 
ATOM   541  C CB  . MET A 1 199 ? 111.446 118.879 118.047 1.00 68.43  ? 199 MET A CB  1 
ATOM   542  C CG  . MET A 1 199 ? 111.411 117.456 118.524 1.00 72.20  ? 199 MET A CG  1 
ATOM   543  S SD  . MET A 1 199 ? 109.971 117.205 119.552 1.00 90.69  ? 199 MET A SD  1 
ATOM   544  C CE  . MET A 1 199 ? 108.691 117.406 118.322 1.00 80.56  ? 199 MET A CE  1 
ATOM   545  N N   . PHE A 1 200 ? 114.463 118.366 116.639 1.00 71.21  ? 200 PHE A N   1 
ATOM   546  C CA  . PHE A 1 200 ? 115.377 118.221 115.512 1.00 72.23  ? 200 PHE A CA  1 
ATOM   547  C C   . PHE A 1 200 ? 115.265 116.804 114.968 1.00 79.45  ? 200 PHE A C   1 
ATOM   548  O O   . PHE A 1 200 ? 115.970 115.901 115.431 1.00 87.77  ? 200 PHE A O   1 
ATOM   549  C CB  . PHE A 1 200 ? 116.799 118.532 115.967 1.00 73.09  ? 200 PHE A CB  1 
ATOM   550  C CG  . PHE A 1 200 ? 116.988 119.947 116.425 1.00 76.63  ? 200 PHE A CG  1 
ATOM   551  C CD1 . PHE A 1 200 ? 116.117 120.942 116.024 1.00 78.58  ? 200 PHE A CD1 1 
ATOM   552  C CD2 . PHE A 1 200 ? 118.085 120.301 117.181 1.00 81.77  ? 200 PHE A CD2 1 
ATOM   553  C CE1 . PHE A 1 200 ? 116.299 122.246 116.423 1.00 81.30  ? 200 PHE A CE1 1 
ATOM   554  C CE2 . PHE A 1 200 ? 118.263 121.604 117.598 1.00 85.64  ? 200 PHE A CE2 1 
ATOM   555  C CZ  . PHE A 1 200 ? 117.377 122.578 117.207 1.00 83.58  ? 200 PHE A CZ  1 
ATOM   556  N N   . ASP A 1 201 ? 114.393 116.609 113.985 1.00 82.69  ? 201 ASP A N   1 
ATOM   557  C CA  . ASP A 1 201 ? 114.180 115.306 113.370 1.00 78.94  ? 201 ASP A CA  1 
ATOM   558  C C   . ASP A 1 201 ? 115.236 115.098 112.294 1.00 80.04  ? 201 ASP A C   1 
ATOM   559  O O   . ASP A 1 201 ? 115.395 115.940 111.402 1.00 87.05  ? 201 ASP A O   1 
ATOM   560  C CB  . ASP A 1 201 ? 112.775 115.210 112.778 1.00 81.70  ? 201 ASP A CB  1 
ATOM   561  C CG  . ASP A 1 201 ? 112.388 113.791 112.412 1.00 90.76  ? 201 ASP A CG  1 
ATOM   562  O OD1 . ASP A 1 201 ? 113.288 112.945 112.228 1.00 95.04  ? 201 ASP A OD1 1 
ATOM   563  O OD2 . ASP A 1 201 ? 111.174 113.518 112.312 1.00 95.21  ? 201 ASP A OD2 1 
ATOM   564  N N   . VAL A 1 202 ? 115.948 113.977 112.377 1.00 73.66  ? 202 VAL A N   1 
ATOM   565  C CA  . VAL A 1 202 ? 117.031 113.651 111.461 1.00 76.35  ? 202 VAL A CA  1 
ATOM   566  C C   . VAL A 1 202 ? 116.753 112.356 110.701 1.00 83.05  ? 202 VAL A C   1 
ATOM   567  O O   . VAL A 1 202 ? 117.671 111.740 110.171 1.00 84.68  ? 202 VAL A O   1 
ATOM   568  C CB  . VAL A 1 202 ? 118.378 113.578 112.203 1.00 76.72  ? 202 VAL A CB  1 
ATOM   569  C CG1 . VAL A 1 202 ? 118.724 114.926 112.800 1.00 79.19  ? 202 VAL A CG1 1 
ATOM   570  C CG2 . VAL A 1 202 ? 118.320 112.517 113.286 1.00 80.71  ? 202 VAL A CG2 1 
ATOM   571  N N   . GLY A 1 203 ? 115.489 111.933 110.643 1.00 87.01  ? 203 GLY A N   1 
ATOM   572  C CA  . GLY A 1 203 ? 115.152 110.708 109.941 1.00 84.28  ? 203 GLY A CA  1 
ATOM   573  C C   . GLY A 1 203 ? 115.358 110.778 108.443 1.00 83.72  ? 203 GLY A C   1 
ATOM   574  O O   . GLY A 1 203 ? 115.547 109.737 107.806 1.00 86.23  ? 203 GLY A O   1 
ATOM   575  N N   . ALA A 1 204 ? 115.321 111.980 107.867 1.00 88.86  ? 204 ALA A N   1 
ATOM   576  C CA  . ALA A 1 204 ? 115.550 112.121 106.433 1.00 92.17  ? 204 ALA A CA  1 
ATOM   577  C C   . ALA A 1 204 ? 116.975 111.737 106.060 1.00 93.14  ? 204 ALA A C   1 
ATOM   578  O O   . ALA A 1 204 ? 117.209 111.162 104.990 1.00 95.18  ? 204 ALA A O   1 
ATOM   579  C CB  . ALA A 1 204 ? 115.244 113.551 105.991 1.00 92.97  ? 204 ALA A CB  1 
ATOM   580  N N   . GLN A 1 205 ? 117.940 112.054 106.920 1.00 93.93  ? 205 GLN A N   1 
ATOM   581  C CA  . GLN A 1 205 ? 119.337 111.748 106.638 1.00 93.74  ? 205 GLN A CA  1 
ATOM   582  C C   . GLN A 1 205 ? 119.544 110.239 106.601 1.00 97.09  ? 205 GLN A C   1 
ATOM   583  O O   . GLN A 1 205 ? 119.200 109.534 107.555 1.00 100.50 ? 205 GLN A O   1 
ATOM   584  C CB  . GLN A 1 205 ? 120.236 112.386 107.693 1.00 94.47  ? 205 GLN A CB  1 
ATOM   585  C CG  . GLN A 1 205 ? 120.130 113.897 107.765 1.00 93.97  ? 205 GLN A CG  1 
ATOM   586  C CD  . GLN A 1 205 ? 120.640 114.573 106.513 1.00 97.53  ? 205 GLN A CD  1 
ATOM   587  O OE1 . GLN A 1 205 ? 119.925 115.345 105.875 1.00 101.02 ? 205 GLN A OE1 1 
ATOM   588  N NE2 . GLN A 1 205 ? 121.884 114.286 106.152 1.00 97.52  ? 205 GLN A NE2 1 
ATOM   589  N N   . ARG A 1 206 ? 120.105 109.745 105.500 1.00 95.19  ? 206 ARG A N   1 
ATOM   590  C CA  . ARG A 1 206 ? 120.384 108.326 105.328 1.00 95.79  ? 206 ARG A CA  1 
ATOM   591  C C   . ARG A 1 206 ? 121.877 108.023 105.318 1.00 99.51  ? 206 ARG A C   1 
ATOM   592  O O   . ARG A 1 206 ? 122.267 106.878 105.067 1.00 104.16 ? 206 ARG A O   1 
ATOM   593  C CB  . ARG A 1 206 ? 119.730 107.816 104.042 1.00 98.74  ? 206 ARG A CB  1 
ATOM   594  C CG  . ARG A 1 206 ? 120.506 108.144 102.777 1.00 102.38 ? 206 ARG A CG  1 
ATOM   595  C CD  . ARG A 1 206 ? 119.571 108.481 101.627 1.00 104.43 ? 206 ARG A CD  1 
ATOM   596  N NE  . ARG A 1 206 ? 118.417 109.254 102.072 1.00 106.16 ? 206 ARG A NE  1 
ATOM   597  C CZ  . ARG A 1 206 ? 117.511 109.780 101.260 1.00 103.69 ? 206 ARG A CZ  1 
ATOM   598  N NH1 . ARG A 1 206 ? 117.592 109.638 99.948  1.00 102.63 ? 206 ARG A NH1 1 
ATOM   599  N NH2 . ARG A 1 206 ? 116.497 110.468 101.779 1.00 103.54 ? 206 ARG A NH2 1 
ATOM   600  N N   . SER A 1 207 ? 122.715 109.014 105.594 1.00 98.36  ? 207 SER A N   1 
ATOM   601  C CA  . SER A 1 207 ? 124.159 108.853 105.549 1.00 98.86  ? 207 SER A CA  1 
ATOM   602  C C   . SER A 1 207 ? 124.668 108.307 106.883 1.00 103.74 ? 207 SER A C   1 
ATOM   603  O O   . SER A 1 207 ? 123.892 107.996 107.790 1.00 105.81 ? 207 SER A O   1 
ATOM   604  C CB  . SER A 1 207 ? 124.812 110.183 105.194 1.00 98.23  ? 207 SER A CB  1 
ATOM   605  O OG  . SER A 1 207 ? 124.182 111.239 105.894 1.00 99.46  ? 207 SER A OG  1 
ATOM   606  N N   . GLU A 1 208 ? 125.987 108.182 107.011 1.00 106.87 ? 208 GLU A N   1 
ATOM   607  C CA  . GLU A 1 208 ? 126.598 107.701 108.246 1.00 104.97 ? 208 GLU A CA  1 
ATOM   608  C C   . GLU A 1 208 ? 126.379 108.730 109.347 1.00 103.11 ? 208 GLU A C   1 
ATOM   609  O O   . GLU A 1 208 ? 126.923 109.837 109.290 1.00 106.59 ? 208 GLU A O   1 
ATOM   610  C CB  . GLU A 1 208 ? 128.085 107.439 108.033 1.00 103.77 ? 208 GLU A CB  1 
ATOM   611  C CG  . GLU A 1 208 ? 128.459 105.968 108.005 1.00 105.71 ? 208 GLU A CG  1 
ATOM   612  C CD  . GLU A 1 208 ? 129.920 105.732 108.336 1.00 108.73 ? 208 GLU A CD  1 
ATOM   613  O OE1 . GLU A 1 208 ? 130.342 106.087 109.456 1.00 108.90 ? 208 GLU A OE1 1 
ATOM   614  O OE2 . GLU A 1 208 ? 130.647 105.191 107.476 1.00 109.15 ? 208 GLU A OE2 1 
ATOM   615  N N   . ARG A 1 209 ? 125.580 108.367 110.351 1.00 80.17  ? 209 ARG A N   1 
ATOM   616  C CA  . ARG A 1 209 ? 125.230 109.314 111.401 1.00 80.19  ? 209 ARG A CA  1 
ATOM   617  C C   . ARG A 1 209 ? 126.438 109.759 112.210 1.00 79.57  ? 209 ARG A C   1 
ATOM   618  O O   . ARG A 1 209 ? 126.465 110.902 112.679 1.00 88.47  ? 209 ARG A O   1 
ATOM   619  C CB  . ARG A 1 209 ? 124.170 108.707 112.320 1.00 84.60  ? 209 ARG A CB  1 
ATOM   620  C CG  . ARG A 1 209 ? 124.613 107.462 113.064 1.00 87.73  ? 209 ARG A CG  1 
ATOM   621  C CD  . ARG A 1 209 ? 123.702 107.100 114.243 1.00 87.27  ? 209 ARG A CD  1 
ATOM   622  N NE  . ARG A 1 209 ? 122.379 106.634 113.839 1.00 84.76  ? 209 ARG A NE  1 
ATOM   623  C CZ  . ARG A 1 209 ? 121.342 107.415 113.562 1.00 85.80  ? 209 ARG A CZ  1 
ATOM   624  N NH1 . ARG A 1 209 ? 121.403 108.728 113.711 1.00 85.63  ? 209 ARG A NH1 1 
ATOM   625  N NH2 . ARG A 1 209 ? 120.207 106.862 113.145 1.00 83.92  ? 209 ARG A NH2 1 
ATOM   626  N N   . LYS A 1 210 ? 127.451 108.904 112.351 1.00 84.92  ? 210 LYS A N   1 
ATOM   627  C CA  . LYS A 1 210 ? 128.614 109.256 113.154 1.00 94.09  ? 210 LYS A CA  1 
ATOM   628  C C   . LYS A 1 210 ? 129.399 110.421 112.570 1.00 93.20  ? 210 LYS A C   1 
ATOM   629  O O   . LYS A 1 210 ? 130.245 110.987 113.271 1.00 91.45  ? 210 LYS A O   1 
ATOM   630  C CB  . LYS A 1 210 ? 129.528 108.039 113.317 1.00 89.45  ? 210 LYS A CB  1 
ATOM   631  C CG  . LYS A 1 210 ? 130.653 107.953 112.303 1.00 88.03  ? 210 LYS A CG  1 
ATOM   632  C CD  . LYS A 1 210 ? 131.687 106.924 112.722 1.00 85.39  ? 210 LYS A CD  1 
ATOM   633  C CE  . LYS A 1 210 ? 132.888 106.942 111.795 1.00 89.57  ? 210 LYS A CE  1 
ATOM   634  N NZ  . LYS A 1 210 ? 132.509 106.592 110.399 1.00 91.88  ? 210 LYS A NZ  1 
ATOM   635  N N   . LYS A 1 211 ? 129.142 110.793 111.319 1.00 73.44  ? 211 LYS A N   1 
ATOM   636  C CA  . LYS A 1 211 ? 129.790 111.948 110.720 1.00 69.00  ? 211 LYS A CA  1 
ATOM   637  C C   . LYS A 1 211 ? 129.104 113.262 111.060 1.00 76.25  ? 211 LYS A C   1 
ATOM   638  O O   . LYS A 1 211 ? 129.702 114.322 110.854 1.00 82.86  ? 211 LYS A O   1 
ATOM   639  C CB  . LYS A 1 211 ? 129.855 111.791 109.200 1.00 72.09  ? 211 LYS A CB  1 
ATOM   640  C CG  . LYS A 1 211 ? 130.606 110.561 108.741 1.00 78.77  ? 211 LYS A CG  1 
ATOM   641  C CD  . LYS A 1 211 ? 131.953 110.455 109.427 1.00 77.22  ? 211 LYS A CD  1 
ATOM   642  C CE  . LYS A 1 211 ? 132.894 111.558 108.981 1.00 77.08  ? 211 LYS A CE  1 
ATOM   643  N NZ  . LYS A 1 211 ? 134.184 111.504 109.718 1.00 77.38  ? 211 LYS A NZ  1 
ATOM   644  N N   . TRP A 1 212 ? 127.874 113.228 111.574 1.00 73.34  ? 212 TRP A N   1 
ATOM   645  C CA  . TRP A 1 212 ? 127.193 114.465 111.926 1.00 72.18  ? 212 TRP A CA  1 
ATOM   646  C C   . TRP A 1 212 ? 126.537 114.437 113.297 1.00 77.12  ? 212 TRP A C   1 
ATOM   647  O O   . TRP A 1 212 ? 126.029 115.476 113.732 1.00 84.14  ? 212 TRP A O   1 
ATOM   648  C CB  . TRP A 1 212 ? 126.134 114.820 110.871 1.00 68.15  ? 212 TRP A CB  1 
ATOM   649  C CG  . TRP A 1 212 ? 125.179 113.720 110.564 1.00 68.20  ? 212 TRP A CG  1 
ATOM   650  C CD1 . TRP A 1 212 ? 125.245 112.848 109.523 1.00 78.08  ? 212 TRP A CD1 1 
ATOM   651  C CD2 . TRP A 1 212 ? 123.999 113.379 111.298 1.00 69.40  ? 212 TRP A CD2 1 
ATOM   652  N NE1 . TRP A 1 212 ? 124.185 111.979 109.563 1.00 78.46  ? 212 TRP A NE1 1 
ATOM   653  C CE2 . TRP A 1 212 ? 123.404 112.285 110.645 1.00 75.94  ? 212 TRP A CE2 1 
ATOM   654  C CE3 . TRP A 1 212 ? 123.390 113.890 112.446 1.00 72.01  ? 212 TRP A CE3 1 
ATOM   655  C CZ2 . TRP A 1 212 ? 122.232 111.693 111.102 1.00 75.73  ? 212 TRP A CZ2 1 
ATOM   656  C CZ3 . TRP A 1 212 ? 122.227 113.301 112.897 1.00 76.11  ? 212 TRP A CZ3 1 
ATOM   657  C CH2 . TRP A 1 212 ? 121.661 112.214 112.227 1.00 76.01  ? 212 TRP A CH2 1 
ATOM   658  N N   . ILE A 1 213 ? 126.534 113.299 113.992 1.00 75.93  ? 213 ILE A N   1 
ATOM   659  C CA  . ILE A 1 213 ? 125.886 113.236 115.296 1.00 69.82  ? 213 ILE A CA  1 
ATOM   660  C C   . ILE A 1 213 ? 126.576 114.163 116.287 1.00 72.94  ? 213 ILE A C   1 
ATOM   661  O O   . ILE A 1 213 ? 125.942 114.664 117.224 1.00 79.28  ? 213 ILE A O   1 
ATOM   662  C CB  . ILE A 1 213 ? 125.840 111.780 115.796 1.00 69.08  ? 213 ILE A CB  1 
ATOM   663  C CG1 . ILE A 1 213 ? 124.733 111.606 116.834 1.00 73.11  ? 213 ILE A CG1 1 
ATOM   664  C CG2 . ILE A 1 213 ? 127.183 111.353 116.363 1.00 72.52  ? 213 ILE A CG2 1 
ATOM   665  C CD1 . ILE A 1 213 ? 123.430 112.268 116.454 1.00 75.32  ? 213 ILE A CD1 1 
ATOM   666  N N   . HIS A 1 214 ? 127.868 114.437 116.086 1.00 71.47  ? 214 HIS A N   1 
ATOM   667  C CA  . HIS A 1 214 ? 128.573 115.356 116.969 1.00 72.12  ? 214 HIS A CA  1 
ATOM   668  C C   . HIS A 1 214 ? 128.027 116.771 116.876 1.00 75.41  ? 214 HIS A C   1 
ATOM   669  O O   . HIS A 1 214 ? 128.285 117.581 117.772 1.00 82.59  ? 214 HIS A O   1 
ATOM   670  C CB  . HIS A 1 214 ? 130.070 115.354 116.660 1.00 75.17  ? 214 HIS A CB  1 
ATOM   671  C CG  . HIS A 1 214 ? 130.392 115.539 115.211 1.00 74.39  ? 214 HIS A CG  1 
ATOM   672  N ND1 . HIS A 1 214 ? 129.886 116.579 114.461 1.00 76.82  ? 214 HIS A ND1 1 
ATOM   673  C CD2 . HIS A 1 214 ? 131.179 114.822 114.375 1.00 78.03  ? 214 HIS A CD2 1 
ATOM   674  C CE1 . HIS A 1 214 ? 130.343 116.491 113.225 1.00 80.05  ? 214 HIS A CE1 1 
ATOM   675  N NE2 . HIS A 1 214 ? 131.130 115.433 113.147 1.00 84.41  ? 214 HIS A NE2 1 
ATOM   676  N N   . CYS A 1 215 ? 127.282 117.088 115.816 1.00 73.30  ? 215 CYS A N   1 
ATOM   677  C CA  . CYS A 1 215 ? 126.624 118.384 115.740 1.00 72.04  ? 215 CYS A CA  1 
ATOM   678  C C   . CYS A 1 215 ? 125.591 118.560 116.841 1.00 74.65  ? 215 CYS A C   1 
ATOM   679  O O   . CYS A 1 215 ? 125.244 119.698 117.173 1.00 81.15  ? 215 CYS A O   1 
ATOM   680  C CB  . CYS A 1 215 ? 125.962 118.561 114.375 1.00 73.87  ? 215 CYS A CB  1 
ATOM   681  S SG  . CYS A 1 215 ? 127.094 118.424 112.977 1.00 93.88  ? 215 CYS A SG  1 
ATOM   682  N N   . PHE A 1 216 ? 125.101 117.468 117.421 1.00 67.01  ? 216 PHE A N   1 
ATOM   683  C CA  . PHE A 1 216 ? 124.075 117.531 118.449 1.00 65.65  ? 216 PHE A CA  1 
ATOM   684  C C   . PHE A 1 216 ? 124.636 117.391 119.856 1.00 71.78  ? 216 PHE A C   1 
ATOM   685  O O   . PHE A 1 216 ? 123.860 117.295 120.811 1.00 73.11  ? 216 PHE A O   1 
ATOM   686  C CB  . PHE A 1 216 ? 123.017 116.463 118.195 1.00 61.64  ? 216 PHE A CB  1 
ATOM   687  C CG  . PHE A 1 216 ? 122.181 116.728 116.985 1.00 62.93  ? 216 PHE A CG  1 
ATOM   688  C CD1 . PHE A 1 216 ? 121.035 117.492 117.079 1.00 66.81  ? 216 PHE A CD1 1 
ATOM   689  C CD2 . PHE A 1 216 ? 122.548 116.231 115.752 1.00 62.90  ? 216 PHE A CD2 1 
ATOM   690  C CE1 . PHE A 1 216 ? 120.266 117.743 115.970 1.00 68.96  ? 216 PHE A CE1 1 
ATOM   691  C CE2 . PHE A 1 216 ? 121.781 116.480 114.639 1.00 64.99  ? 216 PHE A CE2 1 
ATOM   692  C CZ  . PHE A 1 216 ? 120.640 117.237 114.749 1.00 67.33  ? 216 PHE A CZ  1 
ATOM   693  N N   . GLU A 1 217 ? 125.959 117.374 120.009 1.00 82.80  ? 217 GLU A N   1 
ATOM   694  C CA  . GLU A 1 217 ? 126.551 117.368 121.339 1.00 76.19  ? 217 GLU A CA  1 
ATOM   695  C C   . GLU A 1 217 ? 126.182 118.658 122.055 1.00 78.85  ? 217 GLU A C   1 
ATOM   696  O O   . GLU A 1 217 ? 126.644 119.740 121.680 1.00 85.00  ? 217 GLU A O   1 
ATOM   697  C CB  . GLU A 1 217 ? 128.069 117.208 121.263 1.00 78.91  ? 217 GLU A CB  1 
ATOM   698  C CG  . GLU A 1 217 ? 128.787 117.517 122.562 1.00 82.89  ? 217 GLU A CG  1 
ATOM   699  C CD  . GLU A 1 217 ? 130.294 117.527 122.406 1.00 87.70  ? 217 GLU A CD  1 
ATOM   700  O OE1 . GLU A 1 217 ? 130.773 117.541 121.252 1.00 87.40  ? 217 GLU A OE1 1 
ATOM   701  O OE2 . GLU A 1 217 ? 131.001 117.520 123.435 1.00 88.33  ? 217 GLU A OE2 1 
ATOM   702  N N   . GLY A 1 218 ? 125.343 118.554 123.079 1.00 70.01  ? 218 GLY A N   1 
ATOM   703  C CA  . GLY A 1 218 ? 124.810 119.718 123.760 1.00 68.97  ? 218 GLY A CA  1 
ATOM   704  C C   . GLY A 1 218 ? 123.301 119.807 123.761 1.00 63.39  ? 218 GLY A C   1 
ATOM   705  O O   . GLY A 1 218 ? 122.759 120.773 124.316 1.00 68.97  ? 218 GLY A O   1 
ATOM   706  N N   . VAL A 1 219 ? 122.588 118.856 123.160 1.00 47.52  ? 219 VAL A N   1 
ATOM   707  C CA  . VAL A 1 219 ? 121.137 118.855 123.248 1.00 49.04  ? 219 VAL A CA  1 
ATOM   708  C C   . VAL A 1 219 ? 120.720 118.583 124.686 1.00 54.24  ? 219 VAL A C   1 
ATOM   709  O O   . VAL A 1 219 ? 121.394 117.858 125.429 1.00 63.99  ? 219 VAL A O   1 
ATOM   710  C CB  . VAL A 1 219 ? 120.533 117.815 122.289 1.00 55.38  ? 219 VAL A CB  1 
ATOM   711  C CG1 . VAL A 1 219 ? 120.670 118.281 120.854 1.00 64.00  ? 219 VAL A CG1 1 
ATOM   712  C CG2 . VAL A 1 219 ? 121.198 116.466 122.485 1.00 56.33  ? 219 VAL A CG2 1 
ATOM   713  N N   . THR A 1 220 ? 119.604 119.187 125.093 1.00 59.25  ? 220 THR A N   1 
ATOM   714  C CA  . THR A 1 220 ? 119.100 118.956 126.441 1.00 57.69  ? 220 THR A CA  1 
ATOM   715  C C   . THR A 1 220 ? 118.714 117.498 126.638 1.00 64.03  ? 220 THR A C   1 
ATOM   716  O O   . THR A 1 220 ? 119.008 116.906 127.683 1.00 71.78  ? 220 THR A O   1 
ATOM   717  C CB  . THR A 1 220 ? 117.909 119.869 126.723 1.00 65.05  ? 220 THR A CB  1 
ATOM   718  O OG1 . THR A 1 220 ? 118.310 121.235 126.576 1.00 71.88  ? 220 THR A OG1 1 
ATOM   719  C CG2 . THR A 1 220 ? 117.393 119.650 128.133 1.00 65.97  ? 220 THR A CG2 1 
ATOM   720  N N   . ALA A 1 221 ? 118.069 116.897 125.643 1.00 63.53  ? 221 ALA A N   1 
ATOM   721  C CA  . ALA A 1 221 ? 117.649 115.510 125.756 1.00 68.02  ? 221 ALA A CA  1 
ATOM   722  C C   . ALA A 1 221 ? 117.480 114.916 124.367 1.00 67.45  ? 221 ALA A C   1 
ATOM   723  O O   . ALA A 1 221 ? 117.372 115.634 123.367 1.00 77.89  ? 221 ALA A O   1 
ATOM   724  C CB  . ALA A 1 221 ? 116.351 115.381 126.556 1.00 73.57  ? 221 ALA A CB  1 
ATOM   725  N N   . ILE A 1 222 ? 117.461 113.588 124.325 1.00 47.86  ? 222 ILE A N   1 
ATOM   726  C CA  . ILE A 1 222 ? 117.204 112.827 123.112 1.00 44.23  ? 222 ILE A CA  1 
ATOM   727  C C   . ILE A 1 222 ? 115.860 112.136 123.283 1.00 57.05  ? 222 ILE A C   1 
ATOM   728  O O   . ILE A 1 222 ? 115.710 111.242 124.125 1.00 70.81  ? 222 ILE A O   1 
ATOM   729  C CB  . ILE A 1 222 ? 118.314 111.811 122.825 1.00 52.49  ? 222 ILE A CB  1 
ATOM   730  C CG1 . ILE A 1 222 ? 119.673 112.502 122.782 1.00 62.70  ? 222 ILE A CG1 1 
ATOM   731  C CG2 . ILE A 1 222 ? 118.044 111.096 121.525 1.00 64.15  ? 222 ILE A CG2 1 
ATOM   732  C CD1 . ILE A 1 222 ? 120.830 111.539 122.726 1.00 66.33  ? 222 ILE A CD1 1 
ATOM   733  N N   . ILE A 1 223 ? 114.883 112.544 122.479 1.00 66.55  ? 223 ILE A N   1 
ATOM   734  C CA  . ILE A 1 223 ? 113.553 111.941 122.489 1.00 61.34  ? 223 ILE A CA  1 
ATOM   735  C C   . ILE A 1 223 ? 113.599 110.740 121.549 1.00 67.29  ? 223 ILE A C   1 
ATOM   736  O O   . ILE A 1 223 ? 113.378 110.868 120.344 1.00 75.46  ? 223 ILE A O   1 
ATOM   737  C CB  . ILE A 1 223 ? 112.469 112.939 122.080 1.00 59.63  ? 223 ILE A CB  1 
ATOM   738  C CG1 . ILE A 1 223 ? 112.404 114.089 123.080 1.00 68.25  ? 223 ILE A CG1 1 
ATOM   739  C CG2 . ILE A 1 223 ? 111.118 112.261 122.009 1.00 60.77  ? 223 ILE A CG2 1 
ATOM   740  C CD1 . ILE A 1 223 ? 111.340 115.107 122.755 1.00 71.83  ? 223 ILE A CD1 1 
ATOM   741  N N   . PHE A 1 224 ? 113.901 109.569 122.097 1.00 75.19  ? 224 PHE A N   1 
ATOM   742  C CA  . PHE A 1 224 ? 113.888 108.333 121.331 1.00 71.45  ? 224 PHE A CA  1 
ATOM   743  C C   . PHE A 1 224 ? 112.460 107.823 121.225 1.00 76.42  ? 224 PHE A C   1 
ATOM   744  O O   . PHE A 1 224 ? 111.674 107.961 122.163 1.00 84.19  ? 224 PHE A O   1 
ATOM   745  C CB  . PHE A 1 224 ? 114.776 107.281 121.993 1.00 66.89  ? 224 PHE A CB  1 
ATOM   746  C CG  . PHE A 1 224 ? 115.369 106.300 121.034 1.00 70.50  ? 224 PHE A CG  1 
ATOM   747  C CD1 . PHE A 1 224 ? 114.617 105.252 120.541 1.00 71.81  ? 224 PHE A CD1 1 
ATOM   748  C CD2 . PHE A 1 224 ? 116.682 106.425 120.627 1.00 79.97  ? 224 PHE A CD2 1 
ATOM   749  C CE1 . PHE A 1 224 ? 115.164 104.351 119.656 1.00 78.72  ? 224 PHE A CE1 1 
ATOM   750  C CE2 . PHE A 1 224 ? 117.234 105.525 119.743 1.00 84.41  ? 224 PHE A CE2 1 
ATOM   751  C CZ  . PHE A 1 224 ? 116.474 104.486 119.257 1.00 84.03  ? 224 PHE A CZ  1 
ATOM   752  N N   . CYS A 1 225 ? 112.122 107.246 120.075 1.00 86.33  ? 225 CYS A N   1 
ATOM   753  C CA  . CYS A 1 225 ? 110.800 106.681 119.838 1.00 83.06  ? 225 CYS A CA  1 
ATOM   754  C C   . CYS A 1 225 ? 110.961 105.244 119.368 1.00 91.91  ? 225 CYS A C   1 
ATOM   755  O O   . CYS A 1 225 ? 111.703 104.980 118.416 1.00 95.81  ? 225 CYS A O   1 
ATOM   756  C CB  . CYS A 1 225 ? 110.025 107.503 118.807 1.00 86.10  ? 225 CYS A CB  1 
ATOM   757  S SG  . CYS A 1 225 ? 110.012 109.279 119.131 1.00 108.63 ? 225 CYS A SG  1 
ATOM   758  N N   . VAL A 1 226 ? 110.271 104.320 120.032 1.00 86.27  ? 226 VAL A N   1 
ATOM   759  C CA  . VAL A 1 226 ? 110.335 102.901 119.707 1.00 75.59  ? 226 VAL A CA  1 
ATOM   760  C C   . VAL A 1 226 ? 108.918 102.379 119.548 1.00 75.31  ? 226 VAL A C   1 
ATOM   761  O O   . VAL A 1 226 ? 108.070 102.596 120.421 1.00 85.28  ? 226 VAL A O   1 
ATOM   762  C CB  . VAL A 1 226 ? 111.084 102.100 120.787 1.00 82.86  ? 226 VAL A CB  1 
ATOM   763  C CG1 . VAL A 1 226 ? 110.732 100.623 120.696 1.00 86.03  ? 226 VAL A CG1 1 
ATOM   764  C CG2 . VAL A 1 226 ? 112.576 102.304 120.650 1.00 86.28  ? 226 VAL A CG2 1 
ATOM   765  N N   . ALA A 1 227 ? 108.663 101.693 118.440 1.00 80.39  ? 227 ALA A N   1 
ATOM   766  C CA  . ALA A 1 227 ? 107.359 101.091 118.207 1.00 87.18  ? 227 ALA A CA  1 
ATOM   767  C C   . ALA A 1 227 ? 107.218 99.859  119.088 1.00 86.36  ? 227 ALA A C   1 
ATOM   768  O O   . ALA A 1 227 ? 107.856 98.832  118.838 1.00 91.21  ? 227 ALA A O   1 
ATOM   769  C CB  . ALA A 1 227 ? 107.191 100.728 116.735 1.00 92.56  ? 227 ALA A CB  1 
ATOM   770  N N   . LEU A 1 228 ? 106.386 99.966  120.122 1.00 97.61  ? 228 LEU A N   1 
ATOM   771  C CA  . LEU A 1 228 ? 106.188 98.842  121.028 1.00 97.28  ? 228 LEU A CA  1 
ATOM   772  C C   . LEU A 1 228 ? 105.557 97.661  120.302 1.00 97.94  ? 228 LEU A C   1 
ATOM   773  O O   . LEU A 1 228 ? 105.885 96.503  120.587 1.00 105.57 ? 228 LEU A O   1 
ATOM   774  C CB  . LEU A 1 228 ? 105.341 99.290  122.218 1.00 98.72  ? 228 LEU A CB  1 
ATOM   775  C CG  . LEU A 1 228 ? 105.297 98.441  123.482 1.00 100.71 ? 228 LEU A CG  1 
ATOM   776  C CD1 . LEU A 1 228 ? 106.418 98.825  124.410 1.00 99.91  ? 228 LEU A CD1 1 
ATOM   777  C CD2 . LEU A 1 228 ? 103.963 98.646  124.177 1.00 99.83  ? 228 LEU A CD2 1 
ATOM   778  N N   . SER A 1 229 ? 104.673 97.933  119.345 1.00 95.54  ? 229 SER A N   1 
ATOM   779  C CA  . SER A 1 229 ? 104.022 96.893  118.557 1.00 98.28  ? 229 SER A CA  1 
ATOM   780  C C   . SER A 1 229 ? 104.949 96.233  117.546 1.00 100.10 ? 229 SER A C   1 
ATOM   781  O O   . SER A 1 229 ? 104.537 95.266  116.897 1.00 105.87 ? 229 SER A O   1 
ATOM   782  C CB  . SER A 1 229 ? 102.808 97.468  117.826 1.00 100.87 ? 229 SER A CB  1 
ATOM   783  O OG  . SER A 1 229 ? 103.211 98.330  116.776 1.00 100.26 ? 229 SER A OG  1 
ATOM   784  N N   . ALA A 1 230 ? 106.177 96.722  117.387 1.00 108.66 ? 230 ALA A N   1 
ATOM   785  C CA  . ALA A 1 230 ? 107.099 96.202  116.387 1.00 113.02 ? 230 ALA A CA  1 
ATOM   786  C C   . ALA A 1 230 ? 107.904 95.006  116.886 1.00 113.81 ? 230 ALA A C   1 
ATOM   787  O O   . ALA A 1 230 ? 108.994 94.743  116.365 1.00 112.53 ? 230 ALA A O   1 
ATOM   788  C CB  . ALA A 1 230 ? 108.044 97.307  115.912 1.00 110.15 ? 230 ALA A CB  1 
ATOM   789  N N   . TYR A 1 231 ? 107.398 94.283  117.883 1.00 106.51 ? 231 TYR A N   1 
ATOM   790  C CA  . TYR A 1 231 ? 108.091 93.111  118.399 1.00 101.24 ? 231 TYR A CA  1 
ATOM   791  C C   . TYR A 1 231 ? 107.842 91.856  117.573 1.00 108.12 ? 231 TYR A C   1 
ATOM   792  O O   . TYR A 1 231 ? 108.471 90.827  117.841 1.00 116.50 ? 231 TYR A O   1 
ATOM   793  C CB  . TYR A 1 231 ? 107.691 92.876  119.857 1.00 103.08 ? 231 TYR A CB  1 
ATOM   794  C CG  . TYR A 1 231 ? 106.326 92.260  120.050 1.00 105.57 ? 231 TYR A CG  1 
ATOM   795  C CD1 . TYR A 1 231 ? 105.187 92.889  119.571 1.00 105.20 ? 231 TYR A CD1 1 
ATOM   796  C CD2 . TYR A 1 231 ? 106.172 91.070  120.746 1.00 110.51 ? 231 TYR A CD2 1 
ATOM   797  C CE1 . TYR A 1 231 ? 103.936 92.339  119.754 1.00 109.68 ? 231 TYR A CE1 1 
ATOM   798  C CE2 . TYR A 1 231 ? 104.921 90.512  120.938 1.00 110.89 ? 231 TYR A CE2 1 
ATOM   799  C CZ  . TYR A 1 231 ? 103.807 91.151  120.437 1.00 110.29 ? 231 TYR A CZ  1 
ATOM   800  O OH  . TYR A 1 231 ? 102.558 90.604  120.621 1.00 106.67 ? 231 TYR A OH  1 
ATOM   801  N N   . ASP A 1 232 ? 106.952 91.908  116.585 1.00 114.04 ? 232 ASP A N   1 
ATOM   802  C CA  . ASP A 1 232 ? 106.744 90.807  115.649 1.00 113.73 ? 232 ASP A CA  1 
ATOM   803  C C   . ASP A 1 232 ? 107.167 91.130  114.228 1.00 111.37 ? 232 ASP A C   1 
ATOM   804  O O   . ASP A 1 232 ? 107.806 90.300  113.579 1.00 112.05 ? 232 ASP A O   1 
ATOM   805  C CB  . ASP A 1 232 ? 105.271 90.380  115.637 1.00 114.93 ? 232 ASP A CB  1 
ATOM   806  C CG  . ASP A 1 232 ? 104.648 90.403  117.010 1.00 117.52 ? 232 ASP A CG  1 
ATOM   807  O OD1 . ASP A 1 232 ? 105.361 90.081  117.980 1.00 120.09 ? 232 ASP A OD1 1 
ATOM   808  O OD2 . ASP A 1 232 ? 103.450 90.738  117.121 1.00 114.47 ? 232 ASP A OD2 1 
ATOM   809  N N   . LEU A 1 233 ? 106.821 92.312  113.726 1.00 104.65 ? 233 LEU A N   1 
ATOM   810  C CA  . LEU A 1 233 ? 107.102 92.645  112.338 1.00 104.49 ? 233 LEU A CA  1 
ATOM   811  C C   . LEU A 1 233 ? 108.602 92.662  112.080 1.00 103.44 ? 233 LEU A C   1 
ATOM   812  O O   . LEU A 1 233 ? 109.392 93.101  112.919 1.00 103.62 ? 233 LEU A O   1 
ATOM   813  C CB  . LEU A 1 233 ? 106.492 93.999  111.973 1.00 106.67 ? 233 LEU A CB  1 
ATOM   814  C CG  . LEU A 1 233 ? 104.996 94.239  112.204 1.00 106.55 ? 233 LEU A CG  1 
ATOM   815  C CD1 . LEU A 1 233 ? 104.176 93.020  111.795 1.00 105.30 ? 233 LEU A CD1 1 
ATOM   816  C CD2 . LEU A 1 233 ? 104.685 94.662  113.636 1.00 103.09 ? 233 LEU A CD2 1 
ATOM   817  N N   . VAL A 1 234 ? 108.989 92.173  110.909 1.00 110.42 ? 234 VAL A N   1 
ATOM   818  C CA  . VAL A 1 234 ? 110.383 92.098  110.519 1.00 113.22 ? 234 VAL A CA  1 
ATOM   819  C C   . VAL A 1 234 ? 110.692 93.261  109.586 1.00 114.06 ? 234 VAL A C   1 
ATOM   820  O O   . VAL A 1 234 ? 109.801 93.871  108.988 1.00 112.85 ? 234 VAL A O   1 
ATOM   821  C CB  . VAL A 1 234 ? 110.715 90.741  109.856 1.00 115.97 ? 234 VAL A CB  1 
ATOM   822  C CG1 . VAL A 1 234 ? 110.371 90.769  108.375 1.00 112.25 ? 234 VAL A CG1 1 
ATOM   823  C CG2 . VAL A 1 234 ? 112.173 90.376  110.074 1.00 116.00 ? 234 VAL A CG2 1 
ATOM   824  N N   . LEU A 1 235 ? 111.976 93.584  109.471 1.00 122.09 ? 235 LEU A N   1 
ATOM   825  C CA  . LEU A 1 235 ? 112.399 94.663  108.591 1.00 122.17 ? 235 LEU A CA  1 
ATOM   826  C C   . LEU A 1 235 ? 112.123 94.306  107.136 1.00 124.70 ? 235 LEU A C   1 
ATOM   827  O O   . LEU A 1 235 ? 112.322 93.165  106.710 1.00 124.83 ? 235 LEU A O   1 
ATOM   828  C CB  . LEU A 1 235 ? 113.884 94.957  108.789 1.00 123.17 ? 235 LEU A CB  1 
ATOM   829  C CG  . LEU A 1 235 ? 114.292 95.465  110.172 1.00 122.76 ? 235 LEU A CG  1 
ATOM   830  C CD1 . LEU A 1 235 ? 115.802 95.630  110.260 1.00 122.30 ? 235 LEU A CD1 1 
ATOM   831  C CD2 . LEU A 1 235 ? 113.587 96.774  110.490 1.00 123.63 ? 235 LEU A CD2 1 
ATOM   832  N N   . ALA A 1 236 ? 111.651 95.294  106.374 1.00 134.46 ? 236 ALA A N   1 
ATOM   833  C CA  . ALA A 1 236 ? 111.353 95.062  104.965 1.00 135.42 ? 236 ALA A CA  1 
ATOM   834  C C   . ALA A 1 236 ? 112.620 94.784  104.165 1.00 138.00 ? 236 ALA A C   1 
ATOM   835  O O   . ALA A 1 236 ? 112.625 93.916  103.284 1.00 138.56 ? 236 ALA A O   1 
ATOM   836  C CB  . ALA A 1 236 ? 110.604 96.260  104.384 1.00 133.06 ? 236 ALA A CB  1 
ATOM   837  N N   . GLU A 1 237 ? 113.702 95.512  104.452 1.00 146.75 ? 237 GLU A N   1 
ATOM   838  C CA  . GLU A 1 237 ? 114.930 95.355  103.678 1.00 145.82 ? 237 GLU A CA  1 
ATOM   839  C C   . GLU A 1 237 ? 115.549 93.979  103.893 1.00 145.56 ? 237 GLU A C   1 
ATOM   840  O O   . GLU A 1 237 ? 115.895 93.285  102.929 1.00 145.42 ? 237 GLU A O   1 
ATOM   841  C CB  . GLU A 1 237 ? 115.924 96.456  104.047 1.00 145.71 ? 237 GLU A CB  1 
ATOM   842  C CG  . GLU A 1 237 ? 115.469 97.855  103.665 1.00 146.40 ? 237 GLU A CG  1 
ATOM   843  C CD  . GLU A 1 237 ? 116.416 98.931  104.158 1.00 146.99 ? 237 GLU A CD  1 
ATOM   844  O OE1 . GLU A 1 237 ? 117.337 98.603  104.935 1.00 146.53 ? 237 GLU A OE1 1 
ATOM   845  O OE2 . GLU A 1 237 ? 116.238 100.104 103.769 1.00 146.48 ? 237 GLU A OE2 1 
ATOM   846  N N   . ASP A 1 238 ? 115.697 93.566  105.149 1.00 136.37 ? 238 ASP A N   1 
ATOM   847  C CA  . ASP A 1 238 ? 116.259 92.266  105.486 1.00 134.36 ? 238 ASP A CA  1 
ATOM   848  C C   . ASP A 1 238 ? 115.326 91.558  106.453 1.00 135.39 ? 238 ASP A C   1 
ATOM   849  O O   . ASP A 1 238 ? 114.923 92.138  107.467 1.00 137.29 ? 238 ASP A O   1 
ATOM   850  C CB  . ASP A 1 238 ? 117.655 92.406  106.100 1.00 133.90 ? 238 ASP A CB  1 
ATOM   851  C CG  . ASP A 1 238 ? 118.126 91.131  106.767 1.00 134.88 ? 238 ASP A CG  1 
ATOM   852  O OD1 . ASP A 1 238 ? 118.196 90.092  106.080 1.00 134.01 ? 238 ASP A OD1 1 
ATOM   853  O OD2 . ASP A 1 238 ? 118.426 91.167  107.979 1.00 134.81 ? 238 ASP A OD2 1 
ATOM   854  N N   . GLU A 1 239 ? 114.988 90.310  106.144 1.00 143.84 ? 239 GLU A N   1 
ATOM   855  C CA  . GLU A 1 239 ? 114.079 89.527  106.969 1.00 146.69 ? 239 GLU A CA  1 
ATOM   856  C C   . GLU A 1 239 ? 114.794 88.743  108.061 1.00 146.35 ? 239 GLU A C   1 
ATOM   857  O O   . GLU A 1 239 ? 114.133 88.031  108.824 1.00 144.14 ? 239 GLU A O   1 
ATOM   858  C CB  . GLU A 1 239 ? 113.267 88.568  106.094 1.00 146.86 ? 239 GLU A CB  1 
ATOM   859  C CG  . GLU A 1 239 ? 112.360 89.264  105.093 1.00 146.87 ? 239 GLU A CG  1 
ATOM   860  C CD  . GLU A 1 239 ? 111.554 88.288  104.260 1.00 147.50 ? 239 GLU A CD  1 
ATOM   861  O OE1 . GLU A 1 239 ? 111.695 87.065  104.471 1.00 146.51 ? 239 GLU A OE1 1 
ATOM   862  O OE2 . GLU A 1 239 ? 110.778 88.744  103.394 1.00 146.69 ? 239 GLU A OE2 1 
ATOM   863  N N   . GLU A 1 240 ? 116.116 88.852  108.154 1.00 144.61 ? 240 GLU A N   1 
ATOM   864  C CA  . GLU A 1 240 ? 116.881 88.143  109.169 1.00 144.03 ? 240 GLU A CA  1 
ATOM   865  C C   . GLU A 1 240 ? 117.114 88.970  110.425 1.00 145.11 ? 240 GLU A C   1 
ATOM   866  O O   . GLU A 1 240 ? 117.786 88.494  111.346 1.00 144.41 ? 240 GLU A O   1 
ATOM   867  C CB  . GLU A 1 240 ? 118.227 87.693  108.594 1.00 143.57 ? 240 GLU A CB  1 
ATOM   868  C CG  . GLU A 1 240 ? 118.125 87.052  107.221 1.00 144.72 ? 240 GLU A CG  1 
ATOM   869  C CD  . GLU A 1 240 ? 117.059 85.977  107.160 1.00 145.95 ? 240 GLU A CD  1 
ATOM   870  O OE1 . GLU A 1 240 ? 117.166 84.987  107.915 1.00 145.41 ? 240 GLU A OE1 1 
ATOM   871  O OE2 . GLU A 1 240 ? 116.112 86.122  106.358 1.00 146.12 ? 240 GLU A OE2 1 
ATOM   872  N N   . MET A 1 241 ? 116.582 90.189  110.488 1.00 134.09 ? 241 MET A N   1 
ATOM   873  C CA  . MET A 1 241 ? 116.746 91.057  111.645 1.00 133.26 ? 241 MET A CA  1 
ATOM   874  C C   . MET A 1 241 ? 115.380 91.542  112.106 1.00 130.21 ? 241 MET A C   1 
ATOM   875  O O   . MET A 1 241 ? 114.613 92.092  111.310 1.00 125.89 ? 241 MET A O   1 
ATOM   876  C CB  . MET A 1 241 ? 117.651 92.249  111.318 1.00 132.24 ? 241 MET A CB  1 
ATOM   877  C CG  . MET A 1 241 ? 118.099 93.043  112.533 1.00 133.26 ? 241 MET A CG  1 
ATOM   878  S SD  . MET A 1 241 ? 118.947 92.023  113.754 1.00 138.05 ? 241 MET A SD  1 
ATOM   879  C CE  . MET A 1 241 ? 119.597 93.280  114.852 1.00 130.67 ? 241 MET A CE  1 
ATOM   880  N N   . ASN A 1 242 ? 115.084 91.341  113.386 1.00 118.93 ? 242 ASN A N   1 
ATOM   881  C CA  . ASN A 1 242 ? 113.822 91.790  113.955 1.00 117.12 ? 242 ASN A CA  1 
ATOM   882  C C   . ASN A 1 242 ? 113.824 93.309  114.063 1.00 121.32 ? 242 ASN A C   1 
ATOM   883  O O   . ASN A 1 242 ? 114.851 93.922  114.368 1.00 124.33 ? 242 ASN A O   1 
ATOM   884  C CB  . ASN A 1 242 ? 113.608 91.154  115.330 1.00 116.07 ? 242 ASN A CB  1 
ATOM   885  C CG  . ASN A 1 242 ? 112.251 91.481  115.934 1.00 118.72 ? 242 ASN A CG  1 
ATOM   886  O OD1 . ASN A 1 242 ? 111.585 92.438  115.540 1.00 120.42 ? 242 ASN A OD1 1 
ATOM   887  N ND2 . ASN A 1 242 ? 111.837 90.676  116.905 1.00 118.58 ? 242 ASN A ND2 1 
ATOM   888  N N   . ARG A 1 243 ? 112.663 93.918  113.803 1.00 117.25 ? 243 ARG A N   1 
ATOM   889  C CA  . ARG A 1 243 ? 112.572 95.374  113.849 1.00 116.29 ? 243 ARG A CA  1 
ATOM   890  C C   . ARG A 1 243 ? 112.835 95.903  115.253 1.00 114.49 ? 243 ARG A C   1 
ATOM   891  O O   . ARG A 1 243 ? 113.553 96.896  115.427 1.00 113.24 ? 243 ARG A O   1 
ATOM   892  C CB  . ARG A 1 243 ? 111.206 95.839  113.347 1.00 112.61 ? 243 ARG A CB  1 
ATOM   893  C CG  . ARG A 1 243 ? 110.974 97.323  113.550 1.00 111.79 ? 243 ARG A CG  1 
ATOM   894  C CD  . ARG A 1 243 ? 110.521 98.007  112.275 1.00 112.16 ? 243 ARG A CD  1 
ATOM   895  N NE  . ARG A 1 243 ? 109.089 97.873  112.037 1.00 112.63 ? 243 ARG A NE  1 
ATOM   896  C CZ  . ARG A 1 243 ? 108.544 96.990  111.212 1.00 112.94 ? 243 ARG A CZ  1 
ATOM   897  N NH1 . ARG A 1 243 ? 109.284 96.126  110.538 1.00 114.27 ? 243 ARG A NH1 1 
ATOM   898  N NH2 . ARG A 1 243 ? 107.225 96.980  111.053 1.00 111.78 ? 243 ARG A NH2 1 
ATOM   899  N N   . MET A 1 244 ? 112.262 95.255  116.269 1.00 109.78 ? 244 MET A N   1 
ATOM   900  C CA  . MET A 1 244 ? 112.531 95.666  117.642 1.00 104.75 ? 244 MET A CA  1 
ATOM   901  C C   . MET A 1 244 ? 114.002 95.483  117.985 1.00 105.93 ? 244 MET A C   1 
ATOM   902  O O   . MET A 1 244 ? 114.577 96.278  118.736 1.00 111.96 ? 244 MET A O   1 
ATOM   903  C CB  . MET A 1 244 ? 111.650 94.881  118.611 1.00 102.67 ? 244 MET A CB  1 
ATOM   904  C CG  . MET A 1 244 ? 110.593 95.721  119.301 1.00 104.95 ? 244 MET A CG  1 
ATOM   905  S SD  . MET A 1 244 ? 111.274 96.779  120.590 1.00 119.16 ? 244 MET A SD  1 
ATOM   906  C CE  . MET A 1 244 ? 112.489 95.687  121.318 1.00 111.68 ? 244 MET A CE  1 
ATOM   907  N N   . HIS A 1 245 ? 114.631 94.441  117.438 1.00 105.28 ? 245 HIS A N   1 
ATOM   908  C CA  . HIS A 1 245 ? 116.066 94.261  117.633 1.00 106.84 ? 245 HIS A CA  1 
ATOM   909  C C   . HIS A 1 245 ? 116.857 95.388  116.981 1.00 108.20 ? 245 HIS A C   1 
ATOM   910  O O   . HIS A 1 245 ? 117.861 95.850  117.535 1.00 108.68 ? 245 HIS A O   1 
ATOM   911  C CB  . HIS A 1 245 ? 116.502 92.905  117.084 1.00 105.54 ? 245 HIS A CB  1 
ATOM   912  C CG  . HIS A 1 245 ? 116.339 91.782  118.059 1.00 107.09 ? 245 HIS A CG  1 
ATOM   913  N ND1 . HIS A 1 245 ? 117.370 91.334  118.857 1.00 108.73 ? 245 HIS A ND1 1 
ATOM   914  C CD2 . HIS A 1 245 ? 115.264 91.021  118.371 1.00 109.33 ? 245 HIS A CD2 1 
ATOM   915  C CE1 . HIS A 1 245 ? 116.938 90.343  119.615 1.00 109.81 ? 245 HIS A CE1 1 
ATOM   916  N NE2 . HIS A 1 245 ? 115.663 90.133  119.340 1.00 111.68 ? 245 HIS A NE2 1 
ATOM   917  N N   . GLU A 1 246 ? 116.425 95.841  115.803 1.00 109.64 ? 246 GLU A N   1 
ATOM   918  C CA  . GLU A 1 246 ? 117.078 96.982  115.171 1.00 109.90 ? 246 GLU A CA  1 
ATOM   919  C C   . GLU A 1 246 ? 116.923 98.238  116.017 1.00 111.90 ? 246 GLU A C   1 
ATOM   920  O O   . GLU A 1 246 ? 117.868 99.026  116.156 1.00 114.99 ? 246 GLU A O   1 
ATOM   921  C CB  . GLU A 1 246 ? 116.509 97.205  113.771 1.00 110.58 ? 246 GLU A CB  1 
ATOM   922  C CG  . GLU A 1 246 ? 117.234 98.274  112.973 1.00 112.92 ? 246 GLU A CG  1 
ATOM   923  C CD  . GLU A 1 246 ? 116.492 99.596  112.963 1.00 118.16 ? 246 GLU A CD  1 
ATOM   924  O OE1 . GLU A 1 246 ? 115.353 99.643  113.473 1.00 118.68 ? 246 GLU A OE1 1 
ATOM   925  O OE2 . GLU A 1 246 ? 117.047 100.587 112.445 1.00 118.50 ? 246 GLU A OE2 1 
ATOM   926  N N   . SER A 1 247 ? 115.735 98.445  116.588 1.00 103.12 ? 247 SER A N   1 
ATOM   927  C CA  . SER A 1 247 ? 115.533 99.587  117.471 1.00 101.21 ? 247 SER A CA  1 
ATOM   928  C C   . SER A 1 247 ? 116.433 99.496  118.695 1.00 99.45  ? 247 SER A C   1 
ATOM   929  O O   . SER A 1 247 ? 116.993 100.503 119.140 1.00 100.75 ? 247 SER A O   1 
ATOM   930  C CB  . SER A 1 247 ? 114.066 99.678  117.887 1.00 102.04 ? 247 SER A CB  1 
ATOM   931  O OG  . SER A 1 247 ? 113.217 99.714  116.755 1.00 108.43 ? 247 SER A OG  1 
ATOM   932  N N   . MET A 1 248 ? 116.579 98.294  119.256 1.00 103.48 ? 248 MET A N   1 
ATOM   933  C CA  . MET A 1 248 ? 117.467 98.108  120.398 1.00 103.43 ? 248 MET A CA  1 
ATOM   934  C C   . MET A 1 248 ? 118.912 98.409  120.026 1.00 103.03 ? 248 MET A C   1 
ATOM   935  O O   . MET A 1 248 ? 119.649 99.020  120.809 1.00 109.03 ? 248 MET A O   1 
ATOM   936  C CB  . MET A 1 248 ? 117.340 96.685  120.936 1.00 102.44 ? 248 MET A CB  1 
ATOM   937  C CG  . MET A 1 248 ? 116.464 96.562  122.167 1.00 103.41 ? 248 MET A CG  1 
ATOM   938  S SD  . MET A 1 248 ? 116.455 94.893  122.844 1.00 113.23 ? 248 MET A SD  1 
ATOM   939  C CE  . MET A 1 248 ? 118.196 94.485  122.755 1.00 106.45 ? 248 MET A CE  1 
ATOM   940  N N   . LYS A 1 249 ? 119.341 97.975  118.841 1.00 96.86  ? 249 LYS A N   1 
ATOM   941  C CA  . LYS A 1 249 ? 120.700 98.268  118.397 1.00 98.42  ? 249 LYS A CA  1 
ATOM   942  C C   . LYS A 1 249 ? 120.911 99.767  118.230 1.00 98.30  ? 249 LYS A C   1 
ATOM   943  O O   . LYS A 1 249 ? 121.955 100.303 118.622 1.00 101.14 ? 249 LYS A O   1 
ATOM   944  C CB  . LYS A 1 249 ? 120.997 97.535  117.090 1.00 101.20 ? 249 LYS A CB  1 
ATOM   945  C CG  . LYS A 1 249 ? 122.459 97.160  116.911 1.00 100.31 ? 249 LYS A CG  1 
ATOM   946  C CD  . LYS A 1 249 ? 122.624 96.032  115.906 1.00 100.13 ? 249 LYS A CD  1 
ATOM   947  C CE  . LYS A 1 249 ? 122.840 96.571  114.502 1.00 100.33 ? 249 LYS A CE  1 
ATOM   948  N NZ  . LYS A 1 249 ? 123.760 97.742  114.496 1.00 100.26 ? 249 LYS A NZ  1 
ATOM   949  N N   . LEU A 1 250 ? 119.930 100.459 117.649 1.00 87.01  ? 250 LEU A N   1 
ATOM   950  C CA  . LEU A 1 250 ? 120.034 101.907 117.501 1.00 83.50  ? 250 LEU A CA  1 
ATOM   951  C C   . LEU A 1 250 ? 120.095 102.594 118.860 1.00 85.51  ? 250 LEU A C   1 
ATOM   952  O O   . LEU A 1 250 ? 120.874 103.535 119.059 1.00 89.27  ? 250 LEU A O   1 
ATOM   953  C CB  . LEU A 1 250 ? 118.856 102.429 116.682 1.00 84.23  ? 250 LEU A CB  1 
ATOM   954  C CG  . LEU A 1 250 ? 118.821 103.927 116.384 1.00 85.98  ? 250 LEU A CG  1 
ATOM   955  C CD1 . LEU A 1 250 ? 120.135 104.381 115.775 1.00 88.49  ? 250 LEU A CD1 1 
ATOM   956  C CD2 . LEU A 1 250 ? 117.660 104.249 115.460 1.00 86.26  ? 250 LEU A CD2 1 
ATOM   957  N N   . PHE A 1 251 ? 119.279 102.131 119.809 1.00 82.40  ? 251 PHE A N   1 
ATOM   958  C CA  . PHE A 1 251 ? 119.293 102.695 121.153 1.00 77.96  ? 251 PHE A CA  1 
ATOM   959  C C   . PHE A 1 251 ? 120.643 102.484 121.822 1.00 81.62  ? 251 PHE A C   1 
ATOM   960  O O   . PHE A 1 251 ? 121.172 103.394 122.469 1.00 88.99  ? 251 PHE A O   1 
ATOM   961  C CB  . PHE A 1 251 ? 118.177 102.066 121.983 1.00 78.83  ? 251 PHE A CB  1 
ATOM   962  C CG  . PHE A 1 251 ? 117.903 102.771 123.274 1.00 74.07  ? 251 PHE A CG  1 
ATOM   963  C CD1 . PHE A 1 251 ? 117.294 104.011 123.285 1.00 84.01  ? 251 PHE A CD1 1 
ATOM   964  C CD2 . PHE A 1 251 ? 118.232 102.183 124.479 1.00 76.15  ? 251 PHE A CD2 1 
ATOM   965  C CE1 . PHE A 1 251 ? 117.033 104.655 124.473 1.00 87.26  ? 251 PHE A CE1 1 
ATOM   966  C CE2 . PHE A 1 251 ? 117.971 102.821 125.669 1.00 82.10  ? 251 PHE A CE2 1 
ATOM   967  C CZ  . PHE A 1 251 ? 117.369 104.058 125.667 1.00 87.78  ? 251 PHE A CZ  1 
ATOM   968  N N   . ASP A 1 252 ? 121.216 101.288 121.675 1.00 100.55 ? 252 ASP A N   1 
ATOM   969  C CA  . ASP A 1 252 ? 122.543 101.027 122.222 1.00 100.39 ? 252 ASP A CA  1 
ATOM   970  C C   . ASP A 1 252 ? 123.578 101.947 121.592 1.00 99.05  ? 252 ASP A C   1 
ATOM   971  O O   . ASP A 1 252 ? 124.446 102.489 122.286 1.00 103.07 ? 252 ASP A O   1 
ATOM   972  C CB  . ASP A 1 252 ? 122.915 99.559  122.002 1.00 103.47 ? 252 ASP A CB  1 
ATOM   973  C CG  . ASP A 1 252 ? 124.167 99.141  122.760 1.00 104.55 ? 252 ASP A CG  1 
ATOM   974  O OD1 . ASP A 1 252 ? 125.167 99.886  122.760 1.00 105.14 ? 252 ASP A OD1 1 
ATOM   975  O OD2 . ASP A 1 252 ? 124.157 98.041  123.350 1.00 104.55 ? 252 ASP A OD2 1 
ATOM   976  N N   . SER A 1 253 ? 123.498 102.139 120.275 1.00 83.28  ? 253 SER A N   1 
ATOM   977  C CA  . SER A 1 253 ? 124.467 102.989 119.593 1.00 82.64  ? 253 SER A CA  1 
ATOM   978  C C   . SER A 1 253 ? 124.357 104.437 120.050 1.00 82.77  ? 253 SER A C   1 
ATOM   979  O O   . SER A 1 253 ? 125.370 105.135 120.169 1.00 84.18  ? 253 SER A O   1 
ATOM   980  C CB  . SER A 1 253 ? 124.279 102.891 118.081 1.00 88.16  ? 253 SER A CB  1 
ATOM   981  O OG  . SER A 1 253 ? 125.077 103.849 117.409 1.00 92.77  ? 253 SER A OG  1 
ATOM   982  N N   . ILE A 1 254 ? 123.140 104.910 120.307 1.00 82.24  ? 254 ILE A N   1 
ATOM   983  C CA  . ILE A 1 254 ? 122.966 106.327 120.609 1.00 81.99  ? 254 ILE A CA  1 
ATOM   984  C C   . ILE A 1 254 ? 123.141 106.644 122.096 1.00 84.36  ? 254 ILE A C   1 
ATOM   985  O O   . ILE A 1 254 ? 123.553 107.756 122.440 1.00 92.65  ? 254 ILE A O   1 
ATOM   986  C CB  . ILE A 1 254 ? 121.607 106.825 120.086 1.00 82.75  ? 254 ILE A CB  1 
ATOM   987  C CG1 . ILE A 1 254 ? 121.744 108.255 119.568 1.00 83.05  ? 254 ILE A CG1 1 
ATOM   988  C CG2 . ILE A 1 254 ? 120.540 106.765 121.163 1.00 82.83  ? 254 ILE A CG2 1 
ATOM   989  C CD1 . ILE A 1 254 ? 122.312 108.336 118.171 1.00 85.18  ? 254 ILE A CD1 1 
ATOM   990  N N   . CYS A 1 255 ? 122.842 105.701 122.993 1.00 86.10  ? 255 CYS A N   1 
ATOM   991  C CA  . CYS A 1 255 ? 123.039 105.965 124.415 1.00 86.24  ? 255 CYS A CA  1 
ATOM   992  C C   . CYS A 1 255 ? 124.512 105.911 124.788 1.00 83.78  ? 255 CYS A C   1 
ATOM   993  O O   . CYS A 1 255 ? 124.994 106.743 125.565 1.00 88.54  ? 255 CYS A O   1 
ATOM   994  C CB  . CYS A 1 255 ? 122.249 104.967 125.257 1.00 91.94  ? 255 CYS A CB  1 
ATOM   995  S SG  . CYS A 1 255 ? 120.480 105.012 124.981 1.00 103.93 ? 255 CYS A SG  1 
ATOM   996  N N   . ASN A 1 256 ? 125.239 104.942 124.246 1.00 81.21  ? 256 ASN A N   1 
ATOM   997  C CA  . ASN A 1 256 ? 126.643 104.743 124.565 1.00 86.26  ? 256 ASN A CA  1 
ATOM   998  C C   . ASN A 1 256 ? 127.566 105.533 123.652 1.00 89.23  ? 256 ASN A C   1 
ATOM   999  O O   . ASN A 1 256 ? 128.786 105.356 123.721 1.00 92.17  ? 256 ASN A O   1 
ATOM   1000 C CB  . ASN A 1 256 ? 126.979 103.254 124.500 1.00 87.66  ? 256 ASN A CB  1 
ATOM   1001 C CG  . ASN A 1 256 ? 125.911 102.396 125.140 1.00 88.77  ? 256 ASN A CG  1 
ATOM   1002 O OD1 . ASN A 1 256 ? 125.012 102.905 125.810 1.00 86.87  ? 256 ASN A OD1 1 
ATOM   1003 N ND2 . ASN A 1 256 ? 125.995 101.089 124.932 1.00 90.58  ? 256 ASN A ND2 1 
ATOM   1004 N N   . ASN A 1 257 ? 127.012 106.387 122.794 1.00 78.80  ? 257 ASN A N   1 
ATOM   1005 C CA  . ASN A 1 257 ? 127.832 107.234 121.944 1.00 72.18  ? 257 ASN A CA  1 
ATOM   1006 C C   . ASN A 1 257 ? 128.691 108.160 122.794 1.00 76.97  ? 257 ASN A C   1 
ATOM   1007 O O   . ASN A 1 257 ? 128.266 108.651 123.843 1.00 81.93  ? 257 ASN A O   1 
ATOM   1008 C CB  . ASN A 1 257 ? 126.951 108.054 121.004 1.00 71.11  ? 257 ASN A CB  1 
ATOM   1009 C CG  . ASN A 1 257 ? 127.529 108.160 119.612 1.00 80.46  ? 257 ASN A CG  1 
ATOM   1010 O OD1 . ASN A 1 257 ? 128.743 108.248 119.438 1.00 84.23  ? 257 ASN A OD1 1 
ATOM   1011 N ND2 . ASN A 1 257 ? 126.661 108.154 118.609 1.00 82.41  ? 257 ASN A ND2 1 
ATOM   1012 N N   . LYS A 1 258 ? 129.920 108.394 122.334 1.00 68.13  ? 258 LYS A N   1 
ATOM   1013 C CA  . LYS A 1 258 ? 130.840 109.240 123.082 1.00 63.93  ? 258 LYS A CA  1 
ATOM   1014 C C   . LYS A 1 258 ? 130.365 110.682 123.166 1.00 69.76  ? 258 LYS A C   1 
ATOM   1015 O O   . LYS A 1 258 ? 130.872 111.440 123.999 1.00 72.14  ? 258 LYS A O   1 
ATOM   1016 C CB  . LYS A 1 258 ? 132.230 109.193 122.452 1.00 66.80  ? 258 LYS A CB  1 
ATOM   1017 C CG  . LYS A 1 258 ? 132.240 109.446 120.958 1.00 68.80  ? 258 LYS A CG  1 
ATOM   1018 C CD  . LYS A 1 258 ? 133.656 109.634 120.448 1.00 70.66  ? 258 LYS A CD  1 
ATOM   1019 C CE  . LYS A 1 258 ? 133.699 109.659 118.932 1.00 71.16  ? 258 LYS A CE  1 
ATOM   1020 N NZ  . LYS A 1 258 ? 135.062 109.975 118.425 1.00 71.28  ? 258 LYS A NZ  1 
ATOM   1021 N N   . TRP A 1 259 ? 129.412 111.078 122.328 1.00 75.35  ? 259 TRP A N   1 
ATOM   1022 C CA  . TRP A 1 259 ? 128.910 112.443 122.306 1.00 74.57  ? 259 TRP A CA  1 
ATOM   1023 C C   . TRP A 1 259 ? 127.716 112.656 123.225 1.00 69.93  ? 259 TRP A C   1 
ATOM   1024 O O   . TRP A 1 259 ? 127.255 113.793 123.359 1.00 75.08  ? 259 TRP A O   1 
ATOM   1025 C CB  . TRP A 1 259 ? 128.532 112.837 120.876 1.00 76.22  ? 259 TRP A CB  1 
ATOM   1026 C CG  . TRP A 1 259 ? 129.660 112.704 119.910 1.00 73.06  ? 259 TRP A CG  1 
ATOM   1027 C CD1 . TRP A 1 259 ? 129.734 111.855 118.848 1.00 72.56  ? 259 TRP A CD1 1 
ATOM   1028 C CD2 . TRP A 1 259 ? 130.885 113.442 119.920 1.00 67.77  ? 259 TRP A CD2 1 
ATOM   1029 N NE1 . TRP A 1 259 ? 130.928 112.019 118.193 1.00 69.23  ? 259 TRP A NE1 1 
ATOM   1030 C CE2 . TRP A 1 259 ? 131.653 112.989 118.833 1.00 68.46  ? 259 TRP A CE2 1 
ATOM   1031 C CE3 . TRP A 1 259 ? 131.405 114.443 120.742 1.00 70.66  ? 259 TRP A CE3 1 
ATOM   1032 C CZ2 . TRP A 1 259 ? 132.912 113.500 118.548 1.00 72.43  ? 259 TRP A CZ2 1 
ATOM   1033 C CZ3 . TRP A 1 259 ? 132.654 114.949 120.457 1.00 73.16  ? 259 TRP A CZ3 1 
ATOM   1034 C CH2 . TRP A 1 259 ? 133.394 114.478 119.370 1.00 73.25  ? 259 TRP A CH2 1 
ATOM   1035 N N   . PHE A 1 260 ? 127.207 111.604 123.856 1.00 68.24  ? 260 PHE A N   1 
ATOM   1036 C CA  . PHE A 1 260 ? 126.051 111.702 124.736 1.00 71.62  ? 260 PHE A CA  1 
ATOM   1037 C C   . PHE A 1 260 ? 126.299 110.955 126.036 1.00 79.57  ? 260 PHE A C   1 
ATOM   1038 O O   . PHE A 1 260 ? 125.437 110.221 126.528 1.00 82.13  ? 260 PHE A O   1 
ATOM   1039 C CB  . PHE A 1 260 ? 124.796 111.177 124.047 1.00 72.22  ? 260 PHE A CB  1 
ATOM   1040 C CG  . PHE A 1 260 ? 124.522 111.820 122.723 1.00 70.62  ? 260 PHE A CG  1 
ATOM   1041 C CD1 . PHE A 1 260 ? 123.988 113.091 122.653 1.00 71.72  ? 260 PHE A CD1 1 
ATOM   1042 C CD2 . PHE A 1 260 ? 124.796 111.151 121.547 1.00 73.05  ? 260 PHE A CD2 1 
ATOM   1043 C CE1 . PHE A 1 260 ? 123.733 113.682 121.437 1.00 73.71  ? 260 PHE A CE1 1 
ATOM   1044 C CE2 . PHE A 1 260 ? 124.543 111.738 120.329 1.00 73.64  ? 260 PHE A CE2 1 
ATOM   1045 C CZ  . PHE A 1 260 ? 124.011 113.004 120.274 1.00 71.84  ? 260 PHE A CZ  1 
ATOM   1046 N N   . THR A 1 261 ? 127.485 111.133 126.616 1.00 79.72  ? 261 THR A N   1 
ATOM   1047 C CA  . THR A 1 261 ? 127.808 110.479 127.877 1.00 74.30  ? 261 THR A CA  1 
ATOM   1048 C C   . THR A 1 261 ? 127.005 111.027 129.046 1.00 75.06  ? 261 THR A C   1 
ATOM   1049 O O   . THR A 1 261 ? 127.006 110.411 130.117 1.00 82.40  ? 261 THR A O   1 
ATOM   1050 C CB  . THR A 1 261 ? 129.299 110.619 128.175 1.00 76.73  ? 261 THR A CB  1 
ATOM   1051 O OG1 . THR A 1 261 ? 129.601 111.990 128.459 1.00 75.17  ? 261 THR A OG1 1 
ATOM   1052 C CG2 . THR A 1 261 ? 130.121 110.164 126.983 1.00 78.96  ? 261 THR A CG2 1 
ATOM   1053 N N   . ASP A 1 262 ? 126.333 112.165 128.877 1.00 73.67  ? 262 ASP A N   1 
ATOM   1054 C CA  . ASP A 1 262 ? 125.523 112.732 129.946 1.00 76.60  ? 262 ASP A CA  1 
ATOM   1055 C C   . ASP A 1 262 ? 124.150 113.228 129.520 1.00 80.21  ? 262 ASP A C   1 
ATOM   1056 O O   . ASP A 1 262 ? 123.329 113.506 130.397 1.00 83.45  ? 262 ASP A O   1 
ATOM   1057 C CB  . ASP A 1 262 ? 126.298 113.862 130.655 1.00 84.69  ? 262 ASP A CB  1 
ATOM   1058 C CG  . ASP A 1 262 ? 126.167 115.229 129.972 1.00 89.08  ? 262 ASP A CG  1 
ATOM   1059 O OD1 . ASP A 1 262 ? 125.626 115.345 128.852 1.00 84.53  ? 262 ASP A OD1 1 
ATOM   1060 O OD2 . ASP A 1 262 ? 126.698 116.204 130.543 1.00 90.35  ? 262 ASP A OD2 1 
ATOM   1061 N N   . THR A 1 263 ? 123.871 113.360 128.226 1.00 73.76  ? 263 THR A N   1 
ATOM   1062 C CA  . THR A 1 263 ? 122.570 113.848 127.791 1.00 70.28  ? 263 THR A CA  1 
ATOM   1063 C C   . THR A 1 263 ? 121.495 112.816 128.096 1.00 66.67  ? 263 THR A C   1 
ATOM   1064 O O   . THR A 1 263 ? 121.636 111.638 127.757 1.00 73.21  ? 263 THR A O   1 
ATOM   1065 C CB  . THR A 1 263 ? 122.589 114.161 126.297 1.00 71.72  ? 263 THR A CB  1 
ATOM   1066 O OG1 . THR A 1 263 ? 122.500 112.940 125.554 1.00 74.89  ? 263 THR A OG1 1 
ATOM   1067 C CG2 . THR A 1 263 ? 123.872 114.879 125.920 1.00 72.41  ? 263 THR A CG2 1 
ATOM   1068 N N   . SER A 1 264 ? 120.419 113.259 128.736 1.00 63.45  ? 264 SER A N   1 
ATOM   1069 C CA  . SER A 1 264 ? 119.342 112.355 129.090 1.00 64.48  ? 264 SER A CA  1 
ATOM   1070 C C   . SER A 1 264 ? 118.584 111.919 127.842 1.00 67.73  ? 264 SER A C   1 
ATOM   1071 O O   . SER A 1 264 ? 118.738 112.480 126.754 1.00 80.91  ? 264 SER A O   1 
ATOM   1072 C CB  . SER A 1 264 ? 118.393 113.018 130.083 1.00 73.39  ? 264 SER A CB  1 
ATOM   1073 O OG  . SER A 1 264 ? 119.066 113.360 131.280 1.00 79.76  ? 264 SER A OG  1 
ATOM   1074 N N   . ILE A 1 265 ? 117.755 110.893 128.007 1.00 54.97  ? 265 ILE A N   1 
ATOM   1075 C CA  . ILE A 1 265 ? 116.992 110.317 126.908 1.00 57.49  ? 265 ILE A CA  1 
ATOM   1076 C C   . ILE A 1 265 ? 115.548 110.162 127.352 1.00 56.31  ? 265 ILE A C   1 
ATOM   1077 O O   . ILE A 1 265 ? 115.269 109.473 128.340 1.00 68.93  ? 265 ILE A O   1 
ATOM   1078 C CB  . ILE A 1 265 ? 117.570 108.968 126.458 1.00 58.33  ? 265 ILE A CB  1 
ATOM   1079 C CG1 . ILE A 1 265 ? 118.874 109.191 125.697 1.00 63.78  ? 265 ILE A CG1 1 
ATOM   1080 C CG2 . ILE A 1 265 ? 116.574 108.224 125.594 1.00 58.98  ? 265 ILE A CG2 1 
ATOM   1081 C CD1 . ILE A 1 265 ? 119.978 108.262 126.104 1.00 65.73  ? 265 ILE A CD1 1 
ATOM   1082 N N   . ILE A 1 266 ? 114.633 110.800 126.627 1.00 62.50  ? 266 ILE A N   1 
ATOM   1083 C CA  . ILE A 1 266 ? 113.204 110.623 126.841 1.00 63.69  ? 266 ILE A CA  1 
ATOM   1084 C C   . ILE A 1 266 ? 112.754 109.528 125.882 1.00 68.07  ? 266 ILE A C   1 
ATOM   1085 O O   . ILE A 1 266 ? 112.584 109.759 124.684 1.00 83.02  ? 266 ILE A O   1 
ATOM   1086 C CB  . ILE A 1 266 ? 112.427 111.922 126.627 1.00 66.45  ? 266 ILE A CB  1 
ATOM   1087 C CG1 . ILE A 1 266 ? 112.960 113.020 127.542 1.00 65.93  ? 266 ILE A CG1 1 
ATOM   1088 C CG2 . ILE A 1 266 ? 110.950 111.700 126.879 1.00 73.90  ? 266 ILE A CG2 1 
ATOM   1089 C CD1 . ILE A 1 266 ? 112.885 114.394 126.935 1.00 73.99  ? 266 ILE A CD1 1 
ATOM   1090 N N   . LEU A 1 267 ? 112.571 108.328 126.413 1.00 61.31  ? 267 LEU A N   1 
ATOM   1091 C CA  . LEU A 1 267 ? 112.192 107.173 125.618 1.00 63.69  ? 267 LEU A CA  1 
ATOM   1092 C C   . LEU A 1 267 ? 110.674 107.079 125.554 1.00 60.98  ? 267 LEU A C   1 
ATOM   1093 O O   . LEU A 1 267 ? 109.993 107.165 126.581 1.00 76.33  ? 267 LEU A O   1 
ATOM   1094 C CB  . LEU A 1 267 ? 112.802 105.906 126.217 1.00 66.04  ? 267 LEU A CB  1 
ATOM   1095 C CG  . LEU A 1 267 ? 112.603 104.566 125.523 1.00 67.97  ? 267 LEU A CG  1 
ATOM   1096 C CD1 . LEU A 1 267 ? 113.864 103.749 125.627 1.00 69.04  ? 267 LEU A CD1 1 
ATOM   1097 C CD2 . LEU A 1 267 ? 111.477 103.834 126.193 1.00 70.15  ? 267 LEU A CD2 1 
ATOM   1098 N N   . PHE A 1 268 ? 110.151 106.918 124.343 1.00 55.97  ? 268 PHE A N   1 
ATOM   1099 C CA  . PHE A 1 268 ? 108.720 106.892 124.074 1.00 69.00  ? 268 PHE A CA  1 
ATOM   1100 C C   . PHE A 1 268 ? 108.376 105.536 123.481 1.00 74.98  ? 268 PHE A C   1 
ATOM   1101 O O   . PHE A 1 268 ? 108.780 105.227 122.355 1.00 86.04  ? 268 PHE A O   1 
ATOM   1102 C CB  . PHE A 1 268 ? 108.327 108.012 123.114 1.00 79.19  ? 268 PHE A CB  1 
ATOM   1103 C CG  . PHE A 1 268 ? 107.897 109.272 123.792 1.00 73.62  ? 268 PHE A CG  1 
ATOM   1104 C CD1 . PHE A 1 268 ? 106.922 109.250 124.767 1.00 74.90  ? 268 PHE A CD1 1 
ATOM   1105 C CD2 . PHE A 1 268 ? 108.471 110.481 123.454 1.00 69.88  ? 268 PHE A CD2 1 
ATOM   1106 C CE1 . PHE A 1 268 ? 106.524 110.408 125.388 1.00 79.85  ? 268 PHE A CE1 1 
ATOM   1107 C CE2 . PHE A 1 268 ? 108.080 111.640 124.074 1.00 69.53  ? 268 PHE A CE2 1 
ATOM   1108 C CZ  . PHE A 1 268 ? 107.105 111.604 125.042 1.00 77.03  ? 268 PHE A CZ  1 
ATOM   1109 N N   . LEU A 1 269 ? 107.620 104.735 124.224 1.00 84.10  ? 269 LEU A N   1 
ATOM   1110 C CA  . LEU A 1 269 ? 107.165 103.438 123.735 1.00 84.40  ? 269 LEU A CA  1 
ATOM   1111 C C   . LEU A 1 269 ? 105.801 103.646 123.089 1.00 82.08  ? 269 LEU A C   1 
ATOM   1112 O O   . LEU A 1 269 ? 104.770 103.643 123.766 1.00 86.44  ? 269 LEU A O   1 
ATOM   1113 C CB  . LEU A 1 269 ? 107.132 102.426 124.874 1.00 83.03  ? 269 LEU A CB  1 
ATOM   1114 C CG  . LEU A 1 269 ? 108.543 102.055 125.339 1.00 78.42  ? 269 LEU A CG  1 
ATOM   1115 C CD1 . LEU A 1 269 ? 108.563 100.855 126.261 1.00 84.90  ? 269 LEU A CD1 1 
ATOM   1116 C CD2 . LEU A 1 269 ? 109.431 101.800 124.135 1.00 78.63  ? 269 LEU A CD2 1 
ATOM   1117 N N   . ASN A 1 270 ? 105.797 103.831 121.772 1.00 83.20  ? 270 ASN A N   1 
ATOM   1118 C CA  . ASN A 1 270 ? 104.598 104.229 121.054 1.00 79.83  ? 270 ASN A CA  1 
ATOM   1119 C C   . ASN A 1 270 ? 103.727 103.015 120.749 1.00 82.97  ? 270 ASN A C   1 
ATOM   1120 O O   . ASN A 1 270 ? 104.044 101.881 121.112 1.00 89.44  ? 270 ASN A O   1 
ATOM   1121 C CB  . ASN A 1 270 ? 104.975 104.958 119.769 1.00 88.68  ? 270 ASN A CB  1 
ATOM   1122 C CG  . ASN A 1 270 ? 105.940 106.093 120.011 1.00 95.86  ? 270 ASN A CG  1 
ATOM   1123 O OD1 . ASN A 1 270 ? 106.551 106.184 121.072 1.00 98.27  ? 270 ASN A OD1 1 
ATOM   1124 N ND2 . ASN A 1 270 ? 106.090 106.963 119.024 1.00 93.68  ? 270 ASN A ND2 1 
ATOM   1125 N N   . LYS A 1 271 ? 102.612 103.265 120.063 1.00 92.63  ? 271 LYS A N   1 
ATOM   1126 C CA  . LYS A 1 271 ? 101.700 102.212 119.619 1.00 95.72  ? 271 LYS A CA  1 
ATOM   1127 C C   . LYS A 1 271 ? 101.270 101.326 120.784 1.00 94.50  ? 271 LYS A C   1 
ATOM   1128 O O   . LYS A 1 271 ? 101.230 100.099 120.679 1.00 99.00  ? 271 LYS A O   1 
ATOM   1129 C CB  . LYS A 1 271 ? 102.330 101.378 118.504 1.00 99.34  ? 271 LYS A CB  1 
ATOM   1130 C CG  . LYS A 1 271 ? 103.041 102.202 117.444 1.00 99.61  ? 271 LYS A CG  1 
ATOM   1131 C CD  . LYS A 1 271 ? 102.058 103.005 116.613 1.00 98.41  ? 271 LYS A CD  1 
ATOM   1132 C CE  . LYS A 1 271 ? 102.423 102.961 115.141 1.00 96.00  ? 271 LYS A CE  1 
ATOM   1133 N NZ  . LYS A 1 271 ? 103.897 103.004 114.938 1.00 95.90  ? 271 LYS A NZ  1 
ATOM   1134 N N   . LYS A 1 272 ? 100.972 101.967 121.916 1.00 101.73 ? 272 LYS A N   1 
ATOM   1135 C CA  . LYS A 1 272 ? 100.559 101.214 123.129 1.00 105.74 ? 272 LYS A CA  1 
ATOM   1136 C C   . LYS A 1 272 ? 99.288  100.407 122.832 1.00 106.10 ? 272 LYS A C   1 
ATOM   1137 O O   . LYS A 1 272 ? 99.241  99.219  123.223 1.00 109.27 ? 272 LYS A O   1 
ATOM   1138 C CB  . LYS A 1 272 ? 100.335 102.213 124.269 1.00 105.62 ? 272 LYS A CB  1 
ATOM   1139 C CG  . LYS A 1 272 ? 99.415  101.747 125.386 1.00 106.86 ? 272 LYS A CG  1 
ATOM   1140 C CD  . LYS A 1 272 ? 99.190  102.817 126.447 1.00 105.23 ? 272 LYS A CD  1 
ATOM   1141 C CE  . LYS A 1 272 ? 98.287  102.353 127.544 1.00 105.60 ? 272 LYS A CE  1 
ATOM   1142 N NZ  . LYS A 1 272 ? 98.111  103.385 128.569 1.00 104.04 ? 272 LYS A NZ  1 
ATOM   1143 N N   . ASP A 1 273 ? 98.306  101.018 122.163 1.00 107.92 ? 273 ASP A N   1 
ATOM   1144 C CA  . ASP A 1 273 ? 97.043  100.324 121.934 1.00 109.88 ? 273 ASP A CA  1 
ATOM   1145 C C   . ASP A 1 273 ? 97.168  99.234  120.873 1.00 110.85 ? 273 ASP A C   1 
ATOM   1146 O O   . ASP A 1 273 ? 96.401  98.265  120.897 1.00 111.01 ? 273 ASP A O   1 
ATOM   1147 C CB  . ASP A 1 273 ? 95.933  101.356 121.646 1.00 112.30 ? 273 ASP A CB  1 
ATOM   1148 C CG  . ASP A 1 273 ? 95.757  101.709 120.162 1.00 116.56 ? 273 ASP A CG  1 
ATOM   1149 O OD1 . ASP A 1 273 ? 96.415  101.153 119.266 1.00 115.05 ? 273 ASP A OD1 1 
ATOM   1150 O OD2 . ASP A 1 273 ? 94.958  102.631 119.895 1.00 117.33 ? 273 ASP A OD2 1 
ATOM   1151 N N   . LEU A 1 274 ? 98.108  99.371  119.932 1.00 108.64 ? 274 LEU A N   1 
ATOM   1152 C CA  . LEU A 1 274 ? 98.406  98.257  119.034 1.00 110.02 ? 274 LEU A CA  1 
ATOM   1153 C C   . LEU A 1 274 ? 98.938  97.056  119.805 1.00 110.47 ? 274 LEU A C   1 
ATOM   1154 O O   . LEU A 1 274 ? 98.519  95.918  119.568 1.00 113.33 ? 274 LEU A O   1 
ATOM   1155 C CB  . LEU A 1 274 ? 99.413  98.679  117.962 1.00 111.72 ? 274 LEU A CB  1 
ATOM   1156 C CG  . LEU A 1 274 ? 99.049  99.739  116.920 1.00 112.43 ? 274 LEU A CG  1 
ATOM   1157 C CD1 . LEU A 1 274 ? 100.273 100.072 116.076 1.00 111.46 ? 274 LEU A CD1 1 
ATOM   1158 C CD2 . LEU A 1 274 ? 97.903  99.306  116.038 1.00 110.20 ? 274 LEU A CD2 1 
ATOM   1159 N N   . PHE A 1 275 ? 99.865  97.290  120.734 1.00 102.58 ? 275 PHE A N   1 
ATOM   1160 C CA  . PHE A 1 275 ? 100.385 96.201  121.551 1.00 98.76  ? 275 PHE A CA  1 
ATOM   1161 C C   . PHE A 1 275 ? 99.305  95.632  122.460 1.00 103.53 ? 275 PHE A C   1 
ATOM   1162 O O   . PHE A 1 275 ? 99.293  94.424  122.724 1.00 104.90 ? 275 PHE A O   1 
ATOM   1163 C CB  . PHE A 1 275 ? 101.605 96.705  122.331 1.00 94.78  ? 275 PHE A CB  1 
ATOM   1164 C CG  . PHE A 1 275 ? 102.464 95.617  122.928 1.00 94.50  ? 275 PHE A CG  1 
ATOM   1165 C CD1 . PHE A 1 275 ? 101.963 94.733  123.865 1.00 101.81 ? 275 PHE A CD1 1 
ATOM   1166 C CD2 . PHE A 1 275 ? 103.811 95.560  122.632 1.00 99.65  ? 275 PHE A CD2 1 
ATOM   1167 C CE1 . PHE A 1 275 ? 102.768 93.766  124.428 1.00 105.94 ? 275 PHE A CE1 1 
ATOM   1168 C CE2 . PHE A 1 275 ? 104.621 94.592  123.184 1.00 104.41 ? 275 PHE A CE2 1 
ATOM   1169 C CZ  . PHE A 1 275 ? 104.101 93.696  124.088 1.00 106.47 ? 275 PHE A CZ  1 
ATOM   1170 N N   . GLU A 1 276 ? 98.370  96.473  122.912 1.00 120.77 ? 276 GLU A N   1 
ATOM   1171 C CA  . GLU A 1 276 ? 97.314  96.007  123.806 1.00 120.74 ? 276 GLU A CA  1 
ATOM   1172 C C   . GLU A 1 276 ? 96.525  94.850  123.204 1.00 118.97 ? 276 GLU A C   1 
ATOM   1173 O O   . GLU A 1 276 ? 96.092  93.945  123.926 1.00 120.02 ? 276 GLU A O   1 
ATOM   1174 C CB  . GLU A 1 276 ? 96.379  97.163  124.162 1.00 120.96 ? 276 GLU A CB  1 
ATOM   1175 C CG  . GLU A 1 276 ? 96.381  97.515  125.642 1.00 120.31 ? 276 GLU A CG  1 
ATOM   1176 C CD  . GLU A 1 276 ? 95.876  96.380  126.516 1.00 121.82 ? 276 GLU A CD  1 
ATOM   1177 O OE1 . GLU A 1 276 ? 95.126  95.519  126.010 1.00 120.97 ? 276 GLU A OE1 1 
ATOM   1178 O OE2 . GLU A 1 276 ? 96.241  96.339  127.709 1.00 122.94 ? 276 GLU A OE2 1 
ATOM   1179 N N   . GLU A 1 277 ? 96.322  94.855  121.886 1.00 112.96 ? 277 GLU A N   1 
ATOM   1180 C CA  . GLU A 1 277 ? 95.639  93.739  121.246 1.00 114.26 ? 277 GLU A CA  1 
ATOM   1181 C C   . GLU A 1 277 ? 96.590  92.763  120.569 1.00 117.39 ? 277 GLU A C   1 
ATOM   1182 O O   . GLU A 1 277 ? 96.200  91.618  120.319 1.00 119.13 ? 277 GLU A O   1 
ATOM   1183 C CB  . GLU A 1 277 ? 94.590  94.247  120.239 1.00 116.64 ? 277 GLU A CB  1 
ATOM   1184 C CG  . GLU A 1 277 ? 94.985  95.406  119.311 1.00 119.49 ? 277 GLU A CG  1 
ATOM   1185 C CD  . GLU A 1 277 ? 96.039  95.055  118.267 1.00 121.84 ? 277 GLU A CD  1 
ATOM   1186 O OE1 . GLU A 1 277 ? 96.560  95.987  117.618 1.00 121.80 ? 277 GLU A OE1 1 
ATOM   1187 O OE2 . GLU A 1 277 ? 96.299  93.859  118.035 1.00 121.82 ? 277 GLU A OE2 1 
ATOM   1188 N N   . LYS A 1 278 ? 97.819  93.183  120.266 1.00 116.01 ? 278 LYS A N   1 
ATOM   1189 C CA  . LYS A 1 278 ? 98.766  92.291  119.608 1.00 117.42 ? 278 LYS A CA  1 
ATOM   1190 C C   . LYS A 1 278 ? 99.313  91.227  120.548 1.00 116.85 ? 278 LYS A C   1 
ATOM   1191 O O   . LYS A 1 278 ? 99.732  90.159  120.087 1.00 118.13 ? 278 LYS A O   1 
ATOM   1192 C CB  . LYS A 1 278 ? 99.921  93.097  119.013 1.00 115.44 ? 278 LYS A CB  1 
ATOM   1193 C CG  . LYS A 1 278 ? 100.470 92.531  117.714 1.00 112.69 ? 278 LYS A CG  1 
ATOM   1194 C CD  . LYS A 1 278 ? 100.845 93.636  116.741 1.00 113.34 ? 278 LYS A CD  1 
ATOM   1195 C CE  . LYS A 1 278 ? 101.788 93.133  115.663 1.00 115.20 ? 278 LYS A CE  1 
ATOM   1196 N NZ  . LYS A 1 278 ? 103.188 93.060  116.161 1.00 114.51 ? 278 LYS A NZ  1 
ATOM   1197 N N   . ILE A 1 279 ? 99.337  91.497  121.853 1.00 109.37 ? 279 ILE A N   1 
ATOM   1198 C CA  . ILE A 1 279 ? 99.966  90.563  122.781 1.00 108.53 ? 279 ILE A CA  1 
ATOM   1199 C C   . ILE A 1 279 ? 99.140  89.291  122.939 1.00 111.03 ? 279 ILE A C   1 
ATOM   1200 O O   . ILE A 1 279 ? 99.696  88.191  123.040 1.00 111.53 ? 279 ILE A O   1 
ATOM   1201 C CB  . ILE A 1 279 ? 100.257 91.247  124.131 1.00 110.47 ? 279 ILE A CB  1 
ATOM   1202 C CG1 . ILE A 1 279 ? 101.431 90.545  124.809 1.00 112.11 ? 279 ILE A CG1 1 
ATOM   1203 C CG2 . ILE A 1 279 ? 99.027  91.298  125.034 1.00 110.31 ? 279 ILE A CG2 1 
ATOM   1204 C CD1 . ILE A 1 279 ? 102.597 90.333  123.893 1.00 110.35 ? 279 ILE A CD1 1 
ATOM   1205 N N   . THR A 1 280 ? 97.809  89.405  122.954 1.00 113.74 ? 280 THR A N   1 
ATOM   1206 C CA  . THR A 1 280 ? 96.993  88.227  123.218 1.00 115.11 ? 280 THR A CA  1 
ATOM   1207 C C   . THR A 1 280 ? 96.984  87.252  122.043 1.00 114.41 ? 280 THR A C   1 
ATOM   1208 O O   . THR A 1 280 ? 96.517  86.119  122.201 1.00 115.98 ? 280 THR A O   1 
ATOM   1209 C CB  . THR A 1 280 ? 95.570  88.641  123.606 1.00 115.68 ? 280 THR A CB  1 
ATOM   1210 O OG1 . THR A 1 280 ? 94.963  87.595  124.376 1.00 116.47 ? 280 THR A OG1 1 
ATOM   1211 C CG2 . THR A 1 280 ? 94.726  88.911  122.381 1.00 112.82 ? 280 THR A CG2 1 
ATOM   1212 N N   . HIS A 1 281 ? 97.505  87.654  120.882 1.00 114.21 ? 281 HIS A N   1 
ATOM   1213 C CA  . HIS A 1 281 ? 97.749  86.731  119.775 1.00 114.68 ? 281 HIS A CA  1 
ATOM   1214 C C   . HIS A 1 281 ? 99.195  86.240  119.746 1.00 113.15 ? 281 HIS A C   1 
ATOM   1215 O O   . HIS A 1 281 ? 99.446  85.032  119.781 1.00 115.31 ? 281 HIS A O   1 
ATOM   1216 C CB  . HIS A 1 281 ? 97.400  87.388  118.429 1.00 115.21 ? 281 HIS A CB  1 
ATOM   1217 C CG  . HIS A 1 281 ? 96.281  88.381  118.498 1.00 117.97 ? 281 HIS A CG  1 
ATOM   1218 N ND1 . HIS A 1 281 ? 95.122  88.154  119.210 1.00 116.55 ? 281 HIS A ND1 1 
ATOM   1219 C CD2 . HIS A 1 281 ? 96.141  89.604  117.932 1.00 118.41 ? 281 HIS A CD2 1 
ATOM   1220 C CE1 . HIS A 1 281 ? 94.317  89.194  119.079 1.00 117.60 ? 281 HIS A CE1 1 
ATOM   1221 N NE2 . HIS A 1 281 ? 94.913  90.088  118.311 1.00 118.77 ? 281 HIS A NE2 1 
ATOM   1222 N N   . SER A 1 282 ? 100.155 87.161  119.680 1.00 107.76 ? 282 SER A N   1 
ATOM   1223 C CA  . SER A 1 282 ? 101.538 86.744  119.495 1.00 108.37 ? 282 SER A CA  1 
ATOM   1224 C C   . SER A 1 282 ? 102.350 86.933  120.772 1.00 111.37 ? 282 SER A C   1 
ATOM   1225 O O   . SER A 1 282 ? 102.141 87.906  121.504 1.00 114.15 ? 282 SER A O   1 
ATOM   1226 C CB  . SER A 1 282 ? 102.190 87.535  118.362 1.00 111.49 ? 282 SER A CB  1 
ATOM   1227 O OG  . SER A 1 282 ? 103.583 87.296  118.319 1.00 114.00 ? 282 SER A OG  1 
ATOM   1228 N N   . PRO A 1 283 ? 103.273 86.018  121.050 1.00 105.43 ? 283 PRO A N   1 
ATOM   1229 C CA  . PRO A 1 283 ? 104.084 86.100  122.268 1.00 103.80 ? 283 PRO A CA  1 
ATOM   1230 C C   . PRO A 1 283 ? 105.375 86.886  122.054 1.00 105.29 ? 283 PRO A C   1 
ATOM   1231 O O   . PRO A 1 283 ? 105.797 87.154  120.928 1.00 103.97 ? 283 PRO A O   1 
ATOM   1232 C CB  . PRO A 1 283 ? 104.403 84.633  122.589 1.00 102.05 ? 283 PRO A CB  1 
ATOM   1233 C CG  . PRO A 1 283 ? 104.095 83.856  121.357 1.00 103.59 ? 283 PRO A CG  1 
ATOM   1234 C CD  . PRO A 1 283 ? 103.366 84.711  120.380 1.00 102.44 ? 283 PRO A CD  1 
ATOM   1235 N N   . LEU A 1 284 ? 106.004 87.246  123.177 1.00 109.02 ? 284 LEU A N   1 
ATOM   1236 C CA  . LEU A 1 284 ? 107.309 87.900  123.166 1.00 110.88 ? 284 LEU A CA  1 
ATOM   1237 C C   . LEU A 1 284 ? 108.448 86.971  122.772 1.00 111.96 ? 284 LEU A C   1 
ATOM   1238 O O   . LEU A 1 284 ? 109.562 87.455  122.545 1.00 113.73 ? 284 LEU A O   1 
ATOM   1239 C CB  . LEU A 1 284 ? 107.629 88.488  124.544 1.00 109.53 ? 284 LEU A CB  1 
ATOM   1240 C CG  . LEU A 1 284 ? 107.108 89.877  124.902 1.00 109.55 ? 284 LEU A CG  1 
ATOM   1241 C CD1 . LEU A 1 284 ? 105.591 89.874  124.985 1.00 109.09 ? 284 LEU A CD1 1 
ATOM   1242 C CD2 . LEU A 1 284 ? 107.719 90.347  126.191 1.00 106.55 ? 284 LEU A CD2 1 
ATOM   1243 N N   . THR A 1 285 ? 108.204 85.662  122.692 1.00 112.46 ? 285 THR A N   1 
ATOM   1244 C CA  . THR A 1 285 ? 109.302 84.717  122.510 1.00 114.85 ? 285 THR A CA  1 
ATOM   1245 C C   . THR A 1 285 ? 110.047 84.974  121.207 1.00 114.83 ? 285 THR A C   1 
ATOM   1246 O O   . THR A 1 285 ? 111.275 84.835  121.148 1.00 115.51 ? 285 THR A O   1 
ATOM   1247 C CB  . THR A 1 285 ? 108.771 83.285  122.556 1.00 116.27 ? 285 THR A CB  1 
ATOM   1248 O OG1 . THR A 1 285 ? 108.063 83.082  123.785 1.00 119.82 ? 285 THR A OG1 1 
ATOM   1249 C CG2 . THR A 1 285 ? 109.915 82.284  122.472 1.00 113.39 ? 285 THR A CG2 1 
ATOM   1250 N N   . ILE A 1 286 ? 109.324 85.359  120.153 1.00 108.88 ? 286 ILE A N   1 
ATOM   1251 C CA  . ILE A 1 286 ? 109.971 85.650  118.877 1.00 109.95 ? 286 ILE A CA  1 
ATOM   1252 C C   . ILE A 1 286 ? 110.919 86.834  119.014 1.00 109.77 ? 286 ILE A C   1 
ATOM   1253 O O   . ILE A 1 286 ? 112.051 86.802  118.518 1.00 112.78 ? 286 ILE A O   1 
ATOM   1254 C CB  . ILE A 1 286 ? 108.913 85.893  117.786 1.00 108.61 ? 286 ILE A CB  1 
ATOM   1255 C CG1 . ILE A 1 286 ? 107.692 86.594  118.379 1.00 106.44 ? 286 ILE A CG1 1 
ATOM   1256 C CG2 . ILE A 1 286 ? 108.514 84.579  117.133 1.00 108.65 ? 286 ILE A CG2 1 
ATOM   1257 C CD1 . ILE A 1 286 ? 106.644 86.948  117.355 1.00 108.75 ? 286 ILE A CD1 1 
ATOM   1258 N N   . CYS A 1 287 ? 110.475 87.897  119.686 1.00 111.80 ? 287 CYS A N   1 
ATOM   1259 C CA  . CYS A 1 287 ? 111.344 89.050  119.897 1.00 112.56 ? 287 CYS A CA  1 
ATOM   1260 C C   . CYS A 1 287 ? 112.406 88.746  120.945 1.00 110.44 ? 287 CYS A C   1 
ATOM   1261 O O   . CYS A 1 287 ? 113.606 88.919  120.702 1.00 111.92 ? 287 CYS A O   1 
ATOM   1262 C CB  . CYS A 1 287 ? 110.512 90.266  120.308 1.00 119.27 ? 287 CYS A CB  1 
ATOM   1263 S SG  . CYS A 1 287 ? 111.480 91.764  120.610 1.00 130.34 ? 287 CYS A SG  1 
ATOM   1264 N N   . PHE A 1 288 ? 111.981 88.290  122.120 1.00 109.86 ? 288 PHE A N   1 
ATOM   1265 C CA  . PHE A 1 288 ? 112.888 87.955  123.218 1.00 115.34 ? 288 PHE A CA  1 
ATOM   1266 C C   . PHE A 1 288 ? 112.642 86.523  123.670 1.00 113.29 ? 288 PHE A C   1 
ATOM   1267 O O   . PHE A 1 288 ? 111.692 86.264  124.431 1.00 111.64 ? 288 PHE A O   1 
ATOM   1268 C CB  . PHE A 1 288 ? 112.705 88.924  124.385 1.00 114.25 ? 288 PHE A CB  1 
ATOM   1269 C CG  . PHE A 1 288 ? 112.952 90.358  124.024 1.00 111.33 ? 288 PHE A CG  1 
ATOM   1270 C CD1 . PHE A 1 288 ? 114.019 90.708  123.217 1.00 108.69 ? 288 PHE A CD1 1 
ATOM   1271 C CD2 . PHE A 1 288 ? 112.117 91.356  124.489 1.00 110.03 ? 288 PHE A CD2 1 
ATOM   1272 C CE1 . PHE A 1 288 ? 114.250 92.024  122.884 1.00 108.33 ? 288 PHE A CE1 1 
ATOM   1273 C CE2 . PHE A 1 288 ? 112.343 92.674  124.159 1.00 107.98 ? 288 PHE A CE2 1 
ATOM   1274 C CZ  . PHE A 1 288 ? 113.411 93.007  123.356 1.00 109.18 ? 288 PHE A CZ  1 
ATOM   1275 N N   . PRO A 1 289 ? 113.448 85.560  123.219 1.00 111.97 ? 289 PRO A N   1 
ATOM   1276 C CA  . PRO A 1 289 ? 113.252 84.174  123.679 1.00 109.62 ? 289 PRO A CA  1 
ATOM   1277 C C   . PRO A 1 289 ? 113.368 84.005  125.185 1.00 108.79 ? 289 PRO A C   1 
ATOM   1278 O O   . PRO A 1 289 ? 112.625 83.207  125.768 1.00 108.97 ? 289 PRO A O   1 
ATOM   1279 C CB  . PRO A 1 289 ? 114.348 83.401  122.931 1.00 111.60 ? 289 PRO A CB  1 
ATOM   1280 C CG  . PRO A 1 289 ? 114.680 84.255  121.750 1.00 109.82 ? 289 PRO A CG  1 
ATOM   1281 C CD  . PRO A 1 289 ? 114.512 85.668  122.208 1.00 110.82 ? 289 PRO A CD  1 
ATOM   1282 N N   . GLU A 1 290 ? 114.275 84.735  125.838 1.00 111.50 ? 290 GLU A N   1 
ATOM   1283 C CA  . GLU A 1 290 ? 114.465 84.610  127.284 1.00 112.43 ? 290 GLU A CA  1 
ATOM   1284 C C   . GLU A 1 290 ? 113.413 85.458  128.001 1.00 111.23 ? 290 GLU A C   1 
ATOM   1285 O O   . GLU A 1 290 ? 113.680 86.534  128.541 1.00 113.95 ? 290 GLU A O   1 
ATOM   1286 C CB  . GLU A 1 290 ? 115.879 85.006  127.701 1.00 111.41 ? 290 GLU A CB  1 
ATOM   1287 C CG  . GLU A 1 290 ? 116.506 86.226  127.007 1.00 111.70 ? 290 GLU A CG  1 
ATOM   1288 C CD  . GLU A 1 290 ? 116.943 85.975  125.571 1.00 113.16 ? 290 GLU A CD  1 
ATOM   1289 O OE1 . GLU A 1 290 ? 118.027 86.467  125.191 1.00 115.30 ? 290 GLU A OE1 1 
ATOM   1290 O OE2 . GLU A 1 290 ? 116.219 85.289  124.823 1.00 110.57 ? 290 GLU A OE2 1 
ATOM   1291 N N   . TYR A 1 291 ? 112.184 84.946  127.998 1.00 106.22 ? 291 TYR A N   1 
ATOM   1292 C CA  . TYR A 1 291 ? 111.047 85.636  128.591 1.00 106.10 ? 291 TYR A CA  1 
ATOM   1293 C C   . TYR A 1 291 ? 110.260 84.665  129.459 1.00 107.59 ? 291 TYR A C   1 
ATOM   1294 O O   . TYR A 1 291 ? 110.047 83.513  129.070 1.00 110.10 ? 291 TYR A O   1 
ATOM   1295 C CB  . TYR A 1 291 ? 110.167 86.253  127.501 1.00 110.34 ? 291 TYR A CB  1 
ATOM   1296 C CG  . TYR A 1 291 ? 108.801 86.690  127.964 1.00 111.05 ? 291 TYR A CG  1 
ATOM   1297 C CD1 . TYR A 1 291 ? 108.620 87.910  128.594 1.00 105.74 ? 291 TYR A CD1 1 
ATOM   1298 C CD2 . TYR A 1 291 ? 107.685 85.909  127.724 1.00 114.86 ? 291 TYR A CD2 1 
ATOM   1299 C CE1 . TYR A 1 291 ? 107.375 88.324  129.007 1.00 105.83 ? 291 TYR A CE1 1 
ATOM   1300 C CE2 . TYR A 1 291 ? 106.437 86.317  128.126 1.00 115.31 ? 291 TYR A CE2 1 
ATOM   1301 C CZ  . TYR A 1 291 ? 106.285 87.523  128.769 1.00 111.56 ? 291 TYR A CZ  1 
ATOM   1302 O OH  . TYR A 1 291 ? 105.034 87.925  129.174 1.00 111.94 ? 291 TYR A OH  1 
ATOM   1303 N N   . THR A 1 292 ? 109.840 85.134  130.637 1.00 113.63 ? 292 THR A N   1 
ATOM   1304 C CA  . THR A 1 292 ? 109.276 84.240  131.646 1.00 116.27 ? 292 THR A CA  1 
ATOM   1305 C C   . THR A 1 292 ? 107.927 83.671  131.218 1.00 118.87 ? 292 THR A C   1 
ATOM   1306 O O   . THR A 1 292 ? 107.720 82.453  131.252 1.00 120.43 ? 292 THR A O   1 
ATOM   1307 C CB  . THR A 1 292 ? 109.144 84.976  132.980 1.00 117.30 ? 292 THR A CB  1 
ATOM   1308 O OG1 . THR A 1 292 ? 107.869 85.628  133.042 1.00 116.53 ? 292 THR A OG1 1 
ATOM   1309 C CG2 . THR A 1 292 ? 110.250 86.008  133.135 1.00 117.98 ? 292 THR A CG2 1 
ATOM   1310 N N   . GLY A 1 293 ? 106.996 84.529  130.819 1.00 117.67 ? 293 GLY A N   1 
ATOM   1311 C CA  . GLY A 1 293 ? 105.662 84.096  130.470 1.00 119.89 ? 293 GLY A CA  1 
ATOM   1312 C C   . GLY A 1 293 ? 104.637 85.117  130.916 1.00 119.06 ? 293 GLY A C   1 
ATOM   1313 O O   . GLY A 1 293 ? 104.963 86.281  131.141 1.00 114.77 ? 293 GLY A O   1 
ATOM   1314 N N   . ALA A 1 294 ? 103.389 84.659  131.050 1.00 123.01 ? 294 ALA A N   1 
ATOM   1315 C CA  . ALA A 1 294 ? 102.265 85.490  131.487 1.00 121.67 ? 294 ALA A CA  1 
ATOM   1316 C C   . ALA A 1 294 ? 102.078 86.688  130.548 1.00 119.81 ? 294 ALA A C   1 
ATOM   1317 O O   . ALA A 1 294 ? 102.288 87.849  130.903 1.00 118.20 ? 294 ALA A O   1 
ATOM   1318 C CB  . ALA A 1 294 ? 102.444 85.933  132.944 1.00 119.92 ? 294 ALA A CB  1 
ATOM   1319 N N   . ASN A 1 295 ? 101.669 86.357  129.324 1.00 112.47 ? 295 ASN A N   1 
ATOM   1320 C CA  . ASN A 1 295 ? 101.641 87.301  128.213 1.00 112.07 ? 295 ASN A CA  1 
ATOM   1321 C C   . ASN A 1 295 ? 100.552 88.357  128.360 1.00 113.62 ? 295 ASN A C   1 
ATOM   1322 O O   . ASN A 1 295 ? 99.553  88.324  127.635 1.00 113.29 ? 295 ASN A O   1 
ATOM   1323 C CB  . ASN A 1 295 ? 101.433 86.551  126.896 1.00 112.70 ? 295 ASN A CB  1 
ATOM   1324 C CG  . ASN A 1 295 ? 102.705 85.930  126.374 1.00 114.43 ? 295 ASN A CG  1 
ATOM   1325 O OD1 . ASN A 1 295 ? 103.613 85.611  127.137 1.00 114.50 ? 295 ASN A OD1 1 
ATOM   1326 N ND2 . ASN A 1 295 ? 102.786 85.772  125.062 1.00 113.25 ? 295 ASN A ND2 1 
ATOM   1327 N N   . LYS A 1 296 ? 100.730 89.294  129.283 1.00 119.58 ? 296 LYS A N   1 
ATOM   1328 C CA  . LYS A 1 296 ? 99.826  90.425  129.438 1.00 119.39 ? 296 LYS A CA  1 
ATOM   1329 C C   . LYS A 1 296 ? 100.551 91.723  129.105 1.00 120.34 ? 296 LYS A C   1 
ATOM   1330 O O   . LYS A 1 296 ? 101.772 91.756  128.936 1.00 120.14 ? 296 LYS A O   1 
ATOM   1331 C CB  . LYS A 1 296 ? 99.253  90.484  130.860 1.00 117.82 ? 296 LYS A CB  1 
ATOM   1332 C CG  . LYS A 1 296 ? 98.435  89.266  131.273 1.00 119.50 ? 296 LYS A CG  1 
ATOM   1333 C CD  . LYS A 1 296 ? 97.179  89.100  130.436 1.00 122.00 ? 296 LYS A CD  1 
ATOM   1334 C CE  . LYS A 1 296 ? 96.345  87.923  130.915 1.00 121.26 ? 296 LYS A CE  1 
ATOM   1335 N NZ  . LYS A 1 296 ? 95.125  87.739  130.083 1.00 119.79 ? 296 LYS A NZ  1 
ATOM   1336 N N   . TYR A 1 297 ? 99.773  92.805  129.011 1.00 117.81 ? 297 TYR A N   1 
ATOM   1337 C CA  . TYR A 1 297 ? 100.349 94.108  128.692 1.00 115.86 ? 297 TYR A CA  1 
ATOM   1338 C C   . TYR A 1 297 ? 101.365 94.535  129.744 1.00 115.09 ? 297 TYR A C   1 
ATOM   1339 O O   . TYR A 1 297 ? 102.477 94.957  129.412 1.00 113.79 ? 297 TYR A O   1 
ATOM   1340 C CB  . TYR A 1 297 ? 99.243  95.160  128.572 1.00 113.63 ? 297 TYR A CB  1 
ATOM   1341 C CG  . TYR A 1 297 ? 99.738  96.577  128.335 1.00 116.56 ? 297 TYR A CG  1 
ATOM   1342 C CD1 . TYR A 1 297 ? 100.183 96.987  127.084 1.00 117.74 ? 297 TYR A CD1 1 
ATOM   1343 C CD2 . TYR A 1 297 ? 99.806  97.490  129.379 1.00 117.37 ? 297 TYR A CD2 1 
ATOM   1344 C CE1 . TYR A 1 297 ? 100.651 98.267  126.873 1.00 118.79 ? 297 TYR A CE1 1 
ATOM   1345 C CE2 . TYR A 1 297 ? 100.273 98.776  129.176 1.00 117.82 ? 297 TYR A CE2 1 
ATOM   1346 C CZ  . TYR A 1 297 ? 100.695 99.157  127.921 1.00 119.04 ? 297 TYR A CZ  1 
ATOM   1347 O OH  . TYR A 1 297 ? 101.162 100.433 127.711 1.00 118.62 ? 297 TYR A OH  1 
ATOM   1348 N N   . ASP A 1 298 ? 100.999 94.433  131.022 1.00 116.38 ? 298 ASP A N   1 
ATOM   1349 C CA  . ASP A 1 298 ? 101.804 95.053  132.068 1.00 116.24 ? 298 ASP A CA  1 
ATOM   1350 C C   . ASP A 1 298 ? 103.209 94.468  132.109 1.00 113.57 ? 298 ASP A C   1 
ATOM   1351 O O   . ASP A 1 298 ? 104.204 95.199  132.021 1.00 116.48 ? 298 ASP A O   1 
ATOM   1352 C CB  . ASP A 1 298 ? 101.112 94.889  133.420 1.00 118.62 ? 298 ASP A CB  1 
ATOM   1353 C CG  . ASP A 1 298 ? 99.660  95.314  133.383 1.00 120.04 ? 298 ASP A CG  1 
ATOM   1354 O OD1 . ASP A 1 298 ? 99.034  95.195  132.308 1.00 121.06 ? 298 ASP A OD1 1 
ATOM   1355 O OD2 . ASP A 1 298 ? 99.144  95.769  134.425 1.00 118.07 ? 298 ASP A OD2 1 
ATOM   1356 N N   . GLU A 1 299 ? 103.312 93.143  132.205 1.00 109.27 ? 299 GLU A N   1 
ATOM   1357 C CA  . GLU A 1 299 ? 104.626 92.535  132.370 1.00 111.96 ? 299 GLU A CA  1 
ATOM   1358 C C   . GLU A 1 299 ? 105.424 92.590  131.074 1.00 115.95 ? 299 GLU A C   1 
ATOM   1359 O O   . GLU A 1 299 ? 106.648 92.741  131.099 1.00 117.93 ? 299 GLU A O   1 
ATOM   1360 C CB  . GLU A 1 299 ? 104.491 91.102  132.878 1.00 116.01 ? 299 GLU A CB  1 
ATOM   1361 C CG  . GLU A 1 299 ? 103.896 90.997  134.272 1.00 118.93 ? 299 GLU A CG  1 
ATOM   1362 C CD  . GLU A 1 299 ? 104.698 91.757  135.299 1.00 120.39 ? 299 GLU A CD  1 
ATOM   1363 O OE1 . GLU A 1 299 ? 105.944 91.720  135.230 1.00 119.40 ? 299 GLU A OE1 1 
ATOM   1364 O OE2 . GLU A 1 299 ? 104.079 92.408  136.162 1.00 119.76 ? 299 GLU A OE2 1 
ATOM   1365 N N   . ALA A 1 300 ? 104.751 92.472  129.927 1.00 112.57 ? 300 ALA A N   1 
ATOM   1366 C CA  . ALA A 1 300 ? 105.462 92.580  128.655 1.00 113.36 ? 300 ALA A CA  1 
ATOM   1367 C C   . ALA A 1 300 ? 106.059 93.970  128.471 1.00 109.21 ? 300 ALA A C   1 
ATOM   1368 O O   . ALA A 1 300 ? 107.226 94.108  128.078 1.00 107.86 ? 300 ALA A O   1 
ATOM   1369 C CB  . ALA A 1 300 ? 104.523 92.246  127.498 1.00 111.22 ? 300 ALA A CB  1 
ATOM   1370 N N   . ALA A 1 301 ? 105.273 95.010  128.750 1.00 102.64 ? 301 ALA A N   1 
ATOM   1371 C CA  . ALA A 1 301 ? 105.788 96.369  128.657 1.00 105.47 ? 301 ALA A CA  1 
ATOM   1372 C C   . ALA A 1 301 ? 106.910 96.594  129.656 1.00 99.75  ? 301 ALA A C   1 
ATOM   1373 O O   . ALA A 1 301 ? 107.913 97.241  129.336 1.00 104.86 ? 301 ALA A O   1 
ATOM   1374 C CB  . ALA A 1 301 ? 104.660 97.377  128.875 1.00 105.06 ? 301 ALA A CB  1 
ATOM   1375 N N   . SER A 1 302 ? 106.765 96.061  130.872 1.00 90.16  ? 302 SER A N   1 
ATOM   1376 C CA  . SER A 1 302 ? 107.827 96.198  131.860 1.00 94.26  ? 302 SER A CA  1 
ATOM   1377 C C   . SER A 1 302 ? 109.104 95.513  131.393 1.00 96.47  ? 302 SER A C   1 
ATOM   1378 O O   . SER A 1 302 ? 110.204 96.046  131.574 1.00 103.93 ? 302 SER A O   1 
ATOM   1379 C CB  . SER A 1 302 ? 107.368 95.629  133.201 1.00 99.51  ? 302 SER A CB  1 
ATOM   1380 O OG  . SER A 1 302 ? 106.142 96.213  133.605 1.00 102.08 ? 302 SER A OG  1 
ATOM   1381 N N   . TYR A 1 303 ? 108.979 94.329  130.791 1.00 91.58  ? 303 TYR A N   1 
ATOM   1382 C CA  . TYR A 1 303 ? 110.152 93.620  130.294 1.00 94.26  ? 303 TYR A CA  1 
ATOM   1383 C C   . TYR A 1 303 ? 110.831 94.401  129.180 1.00 95.70  ? 303 TYR A C   1 
ATOM   1384 O O   . TYR A 1 303 ? 112.060 94.524  129.160 1.00 93.84  ? 303 TYR A O   1 
ATOM   1385 C CB  . TYR A 1 303 ? 109.762 92.230  129.796 1.00 95.03  ? 303 TYR A CB  1 
ATOM   1386 C CG  . TYR A 1 303 ? 110.944 91.334  129.503 1.00 93.60  ? 303 TYR A CG  1 
ATOM   1387 C CD1 . TYR A 1 303 ? 112.197 91.607  130.028 1.00 94.17  ? 303 TYR A CD1 1 
ATOM   1388 C CD2 . TYR A 1 303 ? 110.815 90.243  128.664 1.00 94.87  ? 303 TYR A CD2 1 
ATOM   1389 C CE1 . TYR A 1 303 ? 113.276 90.797  129.755 1.00 94.43  ? 303 TYR A CE1 1 
ATOM   1390 C CE2 . TYR A 1 303 ? 111.889 89.426  128.381 1.00 98.45  ? 303 TYR A CE2 1 
ATOM   1391 C CZ  . TYR A 1 303 ? 113.119 89.710  128.928 1.00 97.72  ? 303 TYR A CZ  1 
ATOM   1392 O OH  . TYR A 1 303 ? 114.196 88.902  128.650 1.00 100.27 ? 303 TYR A OH  1 
ATOM   1393 N N   . ILE A 1 304 ? 110.049 94.927  128.236 1.00 89.39  ? 304 ILE A N   1 
ATOM   1394 C CA  . ILE A 1 304 ? 110.636 95.693  127.139 1.00 85.59  ? 304 ILE A CA  1 
ATOM   1395 C C   . ILE A 1 304 ? 111.330 96.936  127.679 1.00 85.18  ? 304 ILE A C   1 
ATOM   1396 O O   . ILE A 1 304 ? 112.441 97.283  127.260 1.00 86.81  ? 304 ILE A O   1 
ATOM   1397 C CB  . ILE A 1 304 ? 109.558 96.047  126.098 1.00 83.74  ? 304 ILE A CB  1 
ATOM   1398 C CG1 . ILE A 1 304 ? 109.257 94.837  125.216 1.00 87.87  ? 304 ILE A CG1 1 
ATOM   1399 C CG2 . ILE A 1 304 ? 110.003 97.212  125.239 1.00 87.31  ? 304 ILE A CG2 1 
ATOM   1400 C CD1 . ILE A 1 304 ? 107.899 94.887  124.563 1.00 87.82  ? 304 ILE A CD1 1 
ATOM   1401 N N   . GLN A 1 305 ? 110.688 97.614  128.631 1.00 88.02  ? 305 GLN A N   1 
ATOM   1402 C CA  . GLN A 1 305 ? 111.258 98.808  129.242 1.00 87.62  ? 305 GLN A CA  1 
ATOM   1403 C C   . GLN A 1 305 ? 112.576 98.496  129.943 1.00 87.95  ? 305 GLN A C   1 
ATOM   1404 O O   . GLN A 1 305 ? 113.572 99.215  129.777 1.00 93.38  ? 305 GLN A O   1 
ATOM   1405 C CB  . GLN A 1 305 ? 110.234 99.384  130.220 1.00 86.09  ? 305 GLN A CB  1 
ATOM   1406 C CG  . GLN A 1 305 ? 110.697 100.541 131.055 1.00 81.15  ? 305 GLN A CG  1 
ATOM   1407 C CD  . GLN A 1 305 ? 109.550 101.224 131.765 1.00 87.43  ? 305 GLN A CD  1 
ATOM   1408 O OE1 . GLN A 1 305 ? 108.389 100.860 131.583 1.00 89.37  ? 305 GLN A OE1 1 
ATOM   1409 N NE2 . GLN A 1 305 ? 109.868 102.220 132.583 1.00 89.30  ? 305 GLN A NE2 1 
ATOM   1410 N N   . SER A 1 306 ? 112.598 97.419  130.731 1.00 94.78  ? 306 SER A N   1 
ATOM   1411 C CA  . SER A 1 306 ? 113.815 97.041  131.439 1.00 97.46  ? 306 SER A CA  1 
ATOM   1412 C C   . SER A 1 306 ? 114.912 96.638  130.466 1.00 96.82  ? 306 SER A C   1 
ATOM   1413 O O   . SER A 1 306 ? 116.082 96.981  130.664 1.00 100.54 ? 306 SER A O   1 
ATOM   1414 C CB  . SER A 1 306 ? 113.523 95.908  132.420 1.00 100.03 ? 306 SER A CB  1 
ATOM   1415 O OG  . SER A 1 306 ? 112.565 95.011  131.887 1.00 99.95  ? 306 SER A OG  1 
ATOM   1416 N N   . LYS A 1 307 ? 114.555 95.911  129.407 1.00 87.82  ? 307 LYS A N   1 
ATOM   1417 C CA  . LYS A 1 307 ? 115.547 95.526  128.411 1.00 90.09  ? 307 LYS A CA  1 
ATOM   1418 C C   . LYS A 1 307 ? 116.146 96.750  127.737 1.00 90.14  ? 307 LYS A C   1 
ATOM   1419 O O   . LYS A 1 307 ? 117.359 96.809  127.509 1.00 90.84  ? 307 LYS A O   1 
ATOM   1420 C CB  . LYS A 1 307 ? 114.921 94.596  127.374 1.00 89.06  ? 307 LYS A CB  1 
ATOM   1421 C CG  . LYS A 1 307 ? 115.931 93.911  126.472 1.00 87.60  ? 307 LYS A CG  1 
ATOM   1422 C CD  . LYS A 1 307 ? 116.797 92.935  127.246 1.00 88.18  ? 307 LYS A CD  1 
ATOM   1423 C CE  . LYS A 1 307 ? 115.960 91.833  127.864 1.00 90.72  ? 307 LYS A CE  1 
ATOM   1424 N NZ  . LYS A 1 307 ? 115.136 91.127  126.846 1.00 92.90  ? 307 LYS A NZ  1 
ATOM   1425 N N   . PHE A 1 308 ? 115.313 97.741  127.416 1.00 89.27  ? 308 PHE A N   1 
ATOM   1426 C CA  . PHE A 1 308 ? 115.823 98.947  126.775 1.00 88.70  ? 308 PHE A CA  1 
ATOM   1427 C C   . PHE A 1 308 ? 116.755 99.712  127.705 1.00 88.33  ? 308 PHE A C   1 
ATOM   1428 O O   . PHE A 1 308 ? 117.851 100.117 127.304 1.00 91.19  ? 308 PHE A O   1 
ATOM   1429 C CB  . PHE A 1 308 ? 114.665 99.829  126.312 1.00 85.43  ? 308 PHE A CB  1 
ATOM   1430 C CG  . PHE A 1 308 ? 114.323 99.654  124.865 1.00 85.22  ? 308 PHE A CG  1 
ATOM   1431 C CD1 . PHE A 1 308 ? 115.129 100.195 123.882 1.00 85.35  ? 308 PHE A CD1 1 
ATOM   1432 C CD2 . PHE A 1 308 ? 113.205 98.936  124.487 1.00 86.06  ? 308 PHE A CD2 1 
ATOM   1433 C CE1 . PHE A 1 308 ? 114.822 100.030 122.552 1.00 87.27  ? 308 PHE A CE1 1 
ATOM   1434 C CE2 . PHE A 1 308 ? 112.893 98.770  123.157 1.00 83.78  ? 308 PHE A CE2 1 
ATOM   1435 C CZ  . PHE A 1 308 ? 113.703 99.316  122.189 1.00 86.37  ? 308 PHE A CZ  1 
ATOM   1436 N N   . GLU A 1 309 ? 116.345 99.909  128.962 1.00 82.06  ? 309 GLU A N   1 
ATOM   1437 C CA  . GLU A 1 309 ? 117.237 100.590 129.896 1.00 75.09  ? 309 GLU A CA  1 
ATOM   1438 C C   . GLU A 1 309 ? 118.461 99.767  130.270 1.00 75.87  ? 309 GLU A C   1 
ATOM   1439 O O   . GLU A 1 309 ? 119.418 100.333 130.807 1.00 85.84  ? 309 GLU A O   1 
ATOM   1440 C CB  . GLU A 1 309 ? 116.494 101.007 131.164 1.00 78.80  ? 309 GLU A CB  1 
ATOM   1441 C CG  . GLU A 1 309 ? 115.577 102.197 130.968 1.00 84.57  ? 309 GLU A CG  1 
ATOM   1442 C CD  . GLU A 1 309 ? 114.262 102.063 131.694 1.00 85.10  ? 309 GLU A CD  1 
ATOM   1443 O OE1 . GLU A 1 309 ? 114.270 101.966 132.938 1.00 86.02  ? 309 GLU A OE1 1 
ATOM   1444 O OE2 . GLU A 1 309 ? 113.219 102.094 131.018 1.00 83.69  ? 309 GLU A OE2 1 
ATOM   1445 N N   . ASP A 1 310 ? 118.460 98.460  130.012 1.00 79.81  ? 310 ASP A N   1 
ATOM   1446 C CA  . ASP A 1 310 ? 119.655 97.667  130.262 1.00 87.99  ? 310 ASP A CA  1 
ATOM   1447 C C   . ASP A 1 310 ? 120.802 98.037  129.332 1.00 93.81  ? 310 ASP A C   1 
ATOM   1448 O O   . ASP A 1 310 ? 121.962 97.786  129.673 1.00 99.95  ? 310 ASP A O   1 
ATOM   1449 C CB  . ASP A 1 310 ? 119.341 96.177  130.129 1.00 95.37  ? 310 ASP A CB  1 
ATOM   1450 C CG  . ASP A 1 310 ? 118.723 95.599  131.386 1.00 99.17  ? 310 ASP A CG  1 
ATOM   1451 O OD1 . ASP A 1 310 ? 118.534 96.360  132.358 1.00 97.53  ? 310 ASP A OD1 1 
ATOM   1452 O OD2 . ASP A 1 310 ? 118.429 94.385  131.403 1.00 97.84  ? 310 ASP A OD2 1 
ATOM   1453 N N   . LEU A 1 311 ? 120.509 98.623  128.168 1.00 86.05  ? 311 LEU A N   1 
ATOM   1454 C CA  . LEU A 1 311 ? 121.577 99.047  127.272 1.00 86.91  ? 311 LEU A CA  1 
ATOM   1455 C C   . LEU A 1 311 ? 122.337 100.249 127.811 1.00 86.16  ? 311 LEU A C   1 
ATOM   1456 O O   . LEU A 1 311 ? 123.450 100.520 127.350 1.00 88.66  ? 311 LEU A O   1 
ATOM   1457 C CB  . LEU A 1 311 ? 121.022 99.381  125.887 1.00 85.34  ? 311 LEU A CB  1 
ATOM   1458 C CG  . LEU A 1 311 ? 120.642 98.226  124.958 1.00 86.96  ? 311 LEU A CG  1 
ATOM   1459 C CD1 . LEU A 1 311 ? 121.653 97.094  125.053 1.00 89.91  ? 311 LEU A CD1 1 
ATOM   1460 C CD2 . LEU A 1 311 ? 119.236 97.730  125.229 1.00 87.03  ? 311 LEU A CD2 1 
ATOM   1461 N N   . ASN A 1 312 ? 121.767 100.967 128.771 1.00 84.26  ? 312 ASN A N   1 
ATOM   1462 C CA  . ASN A 1 312 ? 122.380 102.181 129.300 1.00 80.73  ? 312 ASN A CA  1 
ATOM   1463 C C   . ASN A 1 312 ? 123.558 101.742 130.159 1.00 81.60  ? 312 ASN A C   1 
ATOM   1464 O O   . ASN A 1 312 ? 123.396 101.393 131.330 1.00 87.19  ? 312 ASN A O   1 
ATOM   1465 C CB  . ASN A 1 312 ? 121.335 102.982 130.077 1.00 82.54  ? 312 ASN A CB  1 
ATOM   1466 C CG  . ASN A 1 312 ? 121.923 104.068 130.985 1.00 87.60  ? 312 ASN A CG  1 
ATOM   1467 O OD1 . ASN A 1 312 ? 123.120 104.127 131.258 1.00 91.52  ? 312 ASN A OD1 1 
ATOM   1468 N ND2 . ASN A 1 312 ? 121.047 104.945 131.459 1.00 88.23  ? 312 ASN A ND2 1 
ATOM   1469 N N   . LYS A 1 313 ? 124.755 101.737 129.570 1.00 88.05  ? 313 LYS A N   1 
ATOM   1470 C CA  . LYS A 1 313 ? 125.936 101.311 130.314 1.00 91.59  ? 313 LYS A CA  1 
ATOM   1471 C C   . LYS A 1 313 ? 126.340 102.345 131.355 1.00 92.84  ? 313 LYS A C   1 
ATOM   1472 O O   . LYS A 1 313 ? 126.650 101.994 132.499 1.00 94.25  ? 313 LYS A O   1 
ATOM   1473 C CB  . LYS A 1 313 ? 127.094 101.040 129.354 1.00 92.10  ? 313 LYS A CB  1 
ATOM   1474 C CG  . LYS A 1 313 ? 126.859 99.875  128.410 1.00 95.45  ? 313 LYS A CG  1 
ATOM   1475 C CD  . LYS A 1 313 ? 128.165 99.192  128.042 1.00 94.51  ? 313 LYS A CD  1 
ATOM   1476 C CE  . LYS A 1 313 ? 128.289 99.008  126.539 1.00 91.97  ? 313 LYS A CE  1 
ATOM   1477 N NZ  . LYS A 1 313 ? 128.684 100.272 125.862 1.00 91.78  ? 313 LYS A NZ  1 
ATOM   1478 N N   . ARG A 1 314 ? 126.343 103.623 130.981 1.00 94.07  ? 314 ARG A N   1 
ATOM   1479 C CA  . ARG A 1 314 ? 126.764 104.693 131.886 1.00 93.60  ? 314 ARG A CA  1 
ATOM   1480 C C   . ARG A 1 314 ? 125.563 105.200 132.683 1.00 93.34  ? 314 ARG A C   1 
ATOM   1481 O O   . ARG A 1 314 ? 125.043 106.297 132.475 1.00 94.77  ? 314 ARG A O   1 
ATOM   1482 C CB  . ARG A 1 314 ? 127.438 105.815 131.107 1.00 90.83  ? 314 ARG A CB  1 
ATOM   1483 C CG  . ARG A 1 314 ? 128.419 105.336 130.055 1.00 91.48  ? 314 ARG A CG  1 
ATOM   1484 C CD  . ARG A 1 314 ? 129.067 106.505 129.333 1.00 92.74  ? 314 ARG A CD  1 
ATOM   1485 N NE  . ARG A 1 314 ? 129.890 106.064 128.214 1.00 96.55  ? 314 ARG A NE  1 
ATOM   1486 C CZ  . ARG A 1 314 ? 129.654 106.366 126.944 1.00 99.14  ? 314 ARG A CZ  1 
ATOM   1487 N NH1 . ARG A 1 314 ? 128.619 107.111 126.592 1.00 96.32  ? 314 ARG A NH1 1 
ATOM   1488 N NH2 . ARG A 1 314 ? 130.476 105.909 126.005 1.00 96.63  ? 314 ARG A NH2 1 
ATOM   1489 N N   . LYS A 1 315 ? 125.119 104.362 133.615 1.00 80.63  ? 315 LYS A N   1 
ATOM   1490 C CA  . LYS A 1 315 ? 124.088 104.776 134.549 1.00 79.07  ? 315 LYS A CA  1 
ATOM   1491 C C   . LYS A 1 315 ? 124.671 105.746 135.573 1.00 84.50  ? 315 LYS A C   1 
ATOM   1492 O O   . LYS A 1 315 ? 125.885 105.956 135.650 1.00 87.26  ? 315 LYS A O   1 
ATOM   1493 C CB  . LYS A 1 315 ? 123.471 103.564 135.242 1.00 75.10  ? 315 LYS A CB  1 
ATOM   1494 C CG  . LYS A 1 315 ? 122.828 102.575 134.288 1.00 79.50  ? 315 LYS A CG  1 
ATOM   1495 C CD  . LYS A 1 315 ? 122.695 101.199 134.917 1.00 82.07  ? 315 LYS A CD  1 
ATOM   1496 C CE  . LYS A 1 315 ? 121.239 100.842 135.151 1.00 81.27  ? 315 LYS A CE  1 
ATOM   1497 N NZ  . LYS A 1 315 ? 120.485 101.976 135.746 1.00 80.97  ? 315 LYS A NZ  1 
ATOM   1498 N N   . ASP A 1 316 ? 123.781 106.365 136.347 1.00 100.51 ? 316 ASP A N   1 
ATOM   1499 C CA  . ASP A 1 316 ? 124.083 107.360 137.372 1.00 104.00 ? 316 ASP A CA  1 
ATOM   1500 C C   . ASP A 1 316 ? 124.595 108.666 136.772 1.00 100.09 ? 316 ASP A C   1 
ATOM   1501 O O   . ASP A 1 316 ? 124.803 109.634 137.513 1.00 104.91 ? 316 ASP A O   1 
ATOM   1502 C CB  . ASP A 1 316 ? 125.090 106.843 138.412 1.00 108.49 ? 316 ASP A CB  1 
ATOM   1503 C CG  . ASP A 1 316 ? 125.119 107.688 139.672 1.00 112.31 ? 316 ASP A CG  1 
ATOM   1504 O OD1 . ASP A 1 316 ? 124.040 108.133 140.116 1.00 111.80 ? 316 ASP A OD1 1 
ATOM   1505 O OD2 . ASP A 1 316 ? 126.221 107.907 140.218 1.00 111.23 ? 316 ASP A OD2 1 
ATOM   1506 N N   . THR A 1 317 ? 124.792 108.732 135.457 1.00 82.65  ? 317 THR A N   1 
ATOM   1507 C CA  . THR A 1 317 ? 125.099 109.980 134.772 1.00 88.45  ? 317 THR A CA  1 
ATOM   1508 C C   . THR A 1 317 ? 124.178 110.269 133.598 1.00 93.22  ? 317 THR A C   1 
ATOM   1509 O O   . THR A 1 317 ? 124.163 111.410 133.120 1.00 90.55  ? 317 THR A O   1 
ATOM   1510 C CB  . THR A 1 317 ? 126.551 109.987 134.274 1.00 90.76  ? 317 THR A CB  1 
ATOM   1511 O OG1 . THR A 1 317 ? 126.758 108.887 133.380 1.00 93.43  ? 317 THR A OG1 1 
ATOM   1512 C CG2 . THR A 1 317 ? 127.516 109.877 135.439 1.00 89.11  ? 317 THR A CG2 1 
ATOM   1513 N N   . LYS A 1 318 ? 123.417 109.288 133.118 1.00 88.11  ? 318 LYS A N   1 
ATOM   1514 C CA  . LYS A 1 318 ? 122.390 109.493 132.111 1.00 79.78  ? 318 LYS A CA  1 
ATOM   1515 C C   . LYS A 1 318 ? 121.070 108.964 132.645 1.00 77.33  ? 318 LYS A C   1 
ATOM   1516 O O   . LYS A 1 318 ? 121.040 108.063 133.486 1.00 83.17  ? 318 LYS A O   1 
ATOM   1517 C CB  . LYS A 1 318 ? 122.720 108.788 130.791 1.00 81.06  ? 318 LYS A CB  1 
ATOM   1518 C CG  . LYS A 1 318 ? 124.017 109.226 130.147 1.00 83.04  ? 318 LYS A CG  1 
ATOM   1519 C CD  . LYS A 1 318 ? 124.379 108.312 128.991 1.00 81.32  ? 318 LYS A CD  1 
ATOM   1520 C CE  . LYS A 1 318 ? 123.218 108.163 128.028 1.00 81.41  ? 318 LYS A CE  1 
ATOM   1521 N NZ  . LYS A 1 318 ? 122.936 109.437 127.315 1.00 90.49  ? 318 LYS A NZ  1 
ATOM   1522 N N   . GLU A 1 319 ? 119.979 109.528 132.148 1.00 66.67  ? 319 GLU A N   1 
ATOM   1523 C CA  . GLU A 1 319 ? 118.642 109.141 132.567 1.00 67.66  ? 319 GLU A CA  1 
ATOM   1524 C C   . GLU A 1 319 ? 117.838 108.671 131.366 1.00 74.03  ? 319 GLU A C   1 
ATOM   1525 O O   . GLU A 1 319 ? 117.996 109.193 130.258 1.00 79.71  ? 319 GLU A O   1 
ATOM   1526 C CB  . GLU A 1 319 ? 117.924 110.300 133.244 1.00 71.98  ? 319 GLU A CB  1 
ATOM   1527 C CG  . GLU A 1 319 ? 118.505 110.682 134.577 1.00 75.58  ? 319 GLU A CG  1 
ATOM   1528 C CD  . GLU A 1 319 ? 117.660 110.184 135.721 1.00 81.95  ? 319 GLU A CD  1 
ATOM   1529 O OE1 . GLU A 1 319 ? 116.739 109.380 135.472 1.00 82.44  ? 319 GLU A OE1 1 
ATOM   1530 O OE2 . GLU A 1 319 ? 117.916 110.592 136.870 1.00 81.45  ? 319 GLU A OE2 1 
ATOM   1531 N N   . ILE A 1 320 ? 116.980 107.688 131.591 1.00 56.04  ? 320 ILE A N   1 
ATOM   1532 C CA  . ILE A 1 320 ? 116.068 107.187 130.568 1.00 51.42  ? 320 ILE A CA  1 
ATOM   1533 C C   . ILE A 1 320 ? 114.661 107.376 131.120 1.00 52.17  ? 320 ILE A C   1 
ATOM   1534 O O   . ILE A 1 320 ? 114.128 106.517 131.826 1.00 64.41  ? 320 ILE A O   1 
ATOM   1535 C CB  . ILE A 1 320 ? 116.338 105.726 130.204 1.00 56.50  ? 320 ILE A CB  1 
ATOM   1536 C CG1 . ILE A 1 320 ? 117.834 105.491 130.002 1.00 60.80  ? 320 ILE A CG1 1 
ATOM   1537 C CG2 . ILE A 1 320 ? 115.568 105.342 128.954 1.00 62.90  ? 320 ILE A CG2 1 
ATOM   1538 C CD1 . ILE A 1 320 ? 118.402 106.188 128.795 1.00 60.74  ? 320 ILE A CD1 1 
ATOM   1539 N N   . TYR A 1 321 ? 114.049 108.510 130.799 1.00 55.19  ? 321 TYR A N   1 
ATOM   1540 C CA  . TYR A 1 321 ? 112.670 108.776 131.201 1.00 59.37  ? 321 TYR A CA  1 
ATOM   1541 C C   . TYR A 1 321 ? 111.757 108.030 130.240 1.00 63.31  ? 321 TYR A C   1 
ATOM   1542 O O   . TYR A 1 321 ? 111.557 108.454 129.103 1.00 76.15  ? 321 TYR A O   1 
ATOM   1543 C CB  . TYR A 1 321 ? 112.375 110.271 131.189 1.00 64.92  ? 321 TYR A CB  1 
ATOM   1544 C CG  . TYR A 1 321 ? 113.387 111.128 131.911 1.00 65.35  ? 321 TYR A CG  1 
ATOM   1545 C CD1 . TYR A 1 321 ? 114.547 111.547 131.279 1.00 68.08  ? 321 TYR A CD1 1 
ATOM   1546 C CD2 . TYR A 1 321 ? 113.175 111.533 133.218 1.00 60.80  ? 321 TYR A CD2 1 
ATOM   1547 C CE1 . TYR A 1 321 ? 115.467 112.333 131.929 1.00 65.74  ? 321 TYR A CE1 1 
ATOM   1548 C CE2 . TYR A 1 321 ? 114.091 112.320 133.874 1.00 62.62  ? 321 TYR A CE2 1 
ATOM   1549 C CZ  . TYR A 1 321 ? 115.237 112.715 133.227 1.00 66.18  ? 321 TYR A CZ  1 
ATOM   1550 O OH  . TYR A 1 321 ? 116.156 113.501 133.880 1.00 69.28  ? 321 TYR A OH  1 
ATOM   1551 N N   . THR A 1 322 ? 111.204 106.909 130.690 1.00 46.99  ? 322 THR A N   1 
ATOM   1552 C CA  . THR A 1 322 ? 110.401 106.051 129.832 1.00 47.40  ? 322 THR A CA  1 
ATOM   1553 C C   . THR A 1 322 ? 108.928 106.398 129.978 1.00 51.78  ? 322 THR A C   1 
ATOM   1554 O O   . THR A 1 322 ? 108.418 106.502 131.097 1.00 62.41  ? 322 THR A O   1 
ATOM   1555 C CB  . THR A 1 322 ? 110.629 104.581 130.179 1.00 62.03  ? 322 THR A CB  1 
ATOM   1556 O OG1 . THR A 1 322 ? 111.996 104.236 129.925 1.00 72.30  ? 322 THR A OG1 1 
ATOM   1557 C CG2 . THR A 1 322 ? 109.722 103.690 129.348 1.00 65.35  ? 322 THR A CG2 1 
ATOM   1558 N N   . HIS A 1 323 ? 108.248 106.578 128.848 1.00 60.61  ? 323 HIS A N   1 
ATOM   1559 C CA  . HIS A 1 323 ? 106.827 106.895 128.858 1.00 65.95  ? 323 HIS A CA  1 
ATOM   1560 C C   . HIS A 1 323 ? 106.103 106.083 127.798 1.00 69.60  ? 323 HIS A C   1 
ATOM   1561 O O   . HIS A 1 323 ? 106.567 105.986 126.657 1.00 79.88  ? 323 HIS A O   1 
ATOM   1562 C CB  . HIS A 1 323 ? 106.590 108.389 128.620 1.00 67.72  ? 323 HIS A CB  1 
ATOM   1563 C CG  . HIS A 1 323 ? 105.205 108.841 128.961 1.00 73.78  ? 323 HIS A CG  1 
ATOM   1564 N ND1 . HIS A 1 323 ? 104.531 109.796 128.230 1.00 71.88  ? 323 HIS A ND1 1 
ATOM   1565 C CD2 . HIS A 1 323 ? 104.366 108.469 129.956 1.00 76.65  ? 323 HIS A CD2 1 
ATOM   1566 C CE1 . HIS A 1 323 ? 103.337 109.992 128.760 1.00 72.38  ? 323 HIS A CE1 1 
ATOM   1567 N NE2 . HIS A 1 323 ? 103.212 109.200 129.809 1.00 76.17  ? 323 HIS A NE2 1 
ATOM   1568 N N   . PHE A 1 324 ? 104.967 105.508 128.180 1.00 72.32  ? 324 PHE A N   1 
ATOM   1569 C CA  . PHE A 1 324 ? 104.069 104.866 127.230 1.00 77.51  ? 324 PHE A CA  1 
ATOM   1570 C C   . PHE A 1 324 ? 103.142 105.925 126.651 1.00 83.74  ? 324 PHE A C   1 
ATOM   1571 O O   . PHE A 1 324 ? 102.343 106.523 127.380 1.00 87.42  ? 324 PHE A O   1 
ATOM   1572 C CB  . PHE A 1 324 ? 103.268 103.763 127.914 1.00 77.73  ? 324 PHE A CB  1 
ATOM   1573 C CG  . PHE A 1 324 ? 104.116 102.721 128.577 1.00 78.29  ? 324 PHE A CG  1 
ATOM   1574 C CD1 . PHE A 1 324 ? 105.220 102.195 127.933 1.00 77.83  ? 324 PHE A CD1 1 
ATOM   1575 C CD2 . PHE A 1 324 ? 103.813 102.273 129.849 1.00 83.59  ? 324 PHE A CD2 1 
ATOM   1576 C CE1 . PHE A 1 324 ? 106.001 101.238 128.543 1.00 80.09  ? 324 PHE A CE1 1 
ATOM   1577 C CE2 . PHE A 1 324 ? 104.593 101.316 130.463 1.00 85.62  ? 324 PHE A CE2 1 
ATOM   1578 C CZ  . PHE A 1 324 ? 105.688 100.799 129.809 1.00 83.14  ? 324 PHE A CZ  1 
ATOM   1579 N N   . THR A 1 325 ? 103.247 106.160 125.348 1.00 93.59  ? 325 THR A N   1 
ATOM   1580 C CA  . THR A 1 325 ? 102.530 107.266 124.731 1.00 92.08  ? 325 THR A CA  1 
ATOM   1581 C C   . THR A 1 325 ? 101.025 107.033 124.755 1.00 93.42  ? 325 THR A C   1 
ATOM   1582 O O   . THR A 1 325 ? 100.537 105.927 124.513 1.00 91.36  ? 325 THR A O   1 
ATOM   1583 C CB  . THR A 1 325 ? 102.993 107.468 123.292 1.00 95.09  ? 325 THR A CB  1 
ATOM   1584 O OG1 . THR A 1 325 ? 102.292 106.562 122.432 1.00 98.12  ? 325 THR A OG1 1 
ATOM   1585 C CG2 . THR A 1 325 ? 104.482 107.220 123.183 1.00 93.33  ? 325 THR A CG2 1 
ATOM   1586 N N   . CYS A 1 326 ? 100.292 108.101 125.050 1.00 110.44 ? 326 CYS A N   1 
ATOM   1587 C CA  . CYS A 1 326 ? 98.833  108.104 125.044 1.00 113.30 ? 326 CYS A CA  1 
ATOM   1588 C C   . CYS A 1 326 ? 98.398  108.871 123.798 1.00 111.33 ? 326 CYS A C   1 
ATOM   1589 O O   . CYS A 1 326 ? 98.281  110.097 123.814 1.00 109.78 ? 326 CYS A O   1 
ATOM   1590 C CB  . CYS A 1 326 ? 98.278  108.729 126.319 1.00 113.18 ? 326 CYS A CB  1 
ATOM   1591 S SG  . CYS A 1 326 ? 99.036  108.121 127.842 1.00 119.24 ? 326 CYS A SG  1 
ATOM   1592 N N   . SER A 1 327 ? 98.159  108.131 122.712 1.00 112.35 ? 327 SER A N   1 
ATOM   1593 C CA  . SER A 1 327 ? 97.832  108.764 121.438 1.00 114.45 ? 327 SER A CA  1 
ATOM   1594 C C   . SER A 1 327 ? 96.531  109.550 121.514 1.00 116.91 ? 327 SER A C   1 
ATOM   1595 O O   . SER A 1 327 ? 96.328  110.490 120.736 1.00 117.73 ? 327 SER A O   1 
ATOM   1596 C CB  . SER A 1 327 ? 97.750  107.709 120.336 1.00 112.34 ? 327 SER A CB  1 
ATOM   1597 O OG  . SER A 1 327 ? 97.436  108.301 119.088 1.00 112.90 ? 327 SER A OG  1 
ATOM   1598 N N   . THR A 1 328 ? 95.642  109.188 122.435 1.00 128.48 ? 328 THR A N   1 
ATOM   1599 C CA  . THR A 1 328 ? 94.367  109.869 122.596 1.00 130.78 ? 328 THR A CA  1 
ATOM   1600 C C   . THR A 1 328 ? 94.399  110.951 123.665 1.00 130.37 ? 328 THR A C   1 
ATOM   1601 O O   . THR A 1 328 ? 93.360  111.557 123.943 1.00 130.11 ? 328 THR A O   1 
ATOM   1602 C CB  . THR A 1 328 ? 93.267  108.856 122.928 1.00 130.45 ? 328 THR A CB  1 
ATOM   1603 O OG1 . THR A 1 328 ? 93.495  108.313 124.234 1.00 130.17 ? 328 THR A OG1 1 
ATOM   1604 C CG2 . THR A 1 328 ? 93.261  107.726 121.910 1.00 127.41 ? 328 THR A CG2 1 
ATOM   1605 N N   . ASP A 1 329 ? 95.556  111.212 124.269 1.00 121.70 ? 329 ASP A N   1 
ATOM   1606 C CA  . ASP A 1 329 ? 95.666  112.168 125.361 1.00 120.29 ? 329 ASP A CA  1 
ATOM   1607 C C   . ASP A 1 329 ? 96.722  113.216 125.028 1.00 118.70 ? 329 ASP A C   1 
ATOM   1608 O O   . ASP A 1 329 ? 97.380  113.166 123.985 1.00 117.70 ? 329 ASP A O   1 
ATOM   1609 C CB  . ASP A 1 329 ? 95.993  111.463 126.683 1.00 120.86 ? 329 ASP A CB  1 
ATOM   1610 C CG  . ASP A 1 329 ? 95.048  110.315 126.980 1.00 122.60 ? 329 ASP A CG  1 
ATOM   1611 O OD1 . ASP A 1 329 ? 95.067  109.317 126.230 1.00 122.86 ? 329 ASP A OD1 1 
ATOM   1612 O OD2 . ASP A 1 329 ? 94.284  110.412 127.964 1.00 121.90 ? 329 ASP A OD2 1 
ATOM   1613 N N   . THR A 1 330 ? 96.878  114.174 125.941 1.00 103.20 ? 330 THR A N   1 
ATOM   1614 C CA  . THR A 1 330 ? 97.764  115.314 125.753 1.00 104.45 ? 330 THR A CA  1 
ATOM   1615 C C   . THR A 1 330 ? 99.067  115.192 126.536 1.00 102.05 ? 330 THR A C   1 
ATOM   1616 O O   . THR A 1 330 ? 100.086 115.747 126.107 1.00 101.35 ? 330 THR A O   1 
ATOM   1617 C CB  . THR A 1 330 ? 97.023  116.604 126.152 1.00 104.38 ? 330 THR A CB  1 
ATOM   1618 O OG1 . THR A 1 330 ? 96.080  116.946 125.129 1.00 102.96 ? 330 THR A OG1 1 
ATOM   1619 C CG2 . THR A 1 330 ? 97.974  117.779 126.354 1.00 102.28 ? 330 THR A CG2 1 
ATOM   1620 N N   . LYS A 1 331 ? 99.080  114.415 127.619 1.00 87.68  ? 331 LYS A N   1 
ATOM   1621 C CA  . LYS A 1 331 ? 100.193 114.388 128.563 1.00 86.97  ? 331 LYS A CA  1 
ATOM   1622 C C   . LYS A 1 331 ? 101.513 113.947 127.940 1.00 86.05  ? 331 LYS A C   1 
ATOM   1623 O O   . LYS A 1 331 ? 102.540 113.909 128.627 1.00 95.41  ? 331 LYS A O   1 
ATOM   1624 C CB  . LYS A 1 331 ? 99.855  113.471 129.740 1.00 91.41  ? 331 LYS A CB  1 
ATOM   1625 C CG  . LYS A 1 331 ? 98.784  114.015 130.669 1.00 94.12  ? 331 LYS A CG  1 
ATOM   1626 C CD  . LYS A 1 331 ? 98.163  112.905 131.499 1.00 94.64  ? 331 LYS A CD  1 
ATOM   1627 C CE  . LYS A 1 331 ? 97.377  111.942 130.629 1.00 92.64  ? 331 LYS A CE  1 
ATOM   1628 N NZ  . LYS A 1 331 ? 96.437  112.663 129.729 1.00 95.19  ? 331 LYS A NZ  1 
ATOM   1629 N N   . ASN A 1 332 ? 101.505 113.613 126.649 1.00 82.90  ? 332 ASN A N   1 
ATOM   1630 C CA  . ASN A 1 332 ? 102.740 113.213 125.985 1.00 85.76  ? 332 ASN A CA  1 
ATOM   1631 C C   . ASN A 1 332 ? 103.761 114.342 125.995 1.00 85.17  ? 332 ASN A C   1 
ATOM   1632 O O   . ASN A 1 332 ? 104.953 114.109 126.224 1.00 89.61  ? 332 ASN A O   1 
ATOM   1633 C CB  . ASN A 1 332 ? 102.446 112.767 124.555 1.00 89.13  ? 332 ASN A CB  1 
ATOM   1634 C CG  . ASN A 1 332 ? 102.943 111.366 124.270 1.00 98.01  ? 332 ASN A CG  1 
ATOM   1635 O OD1 . ASN A 1 332 ? 103.331 110.636 125.182 1.00 99.82  ? 332 ASN A OD1 1 
ATOM   1636 N ND2 . ASN A 1 332 ? 102.928 110.980 123.001 1.00 97.65  ? 332 ASN A ND2 1 
ATOM   1637 N N   . VAL A 1 333 ? 103.315 115.572 125.749 1.00 77.57  ? 333 VAL A N   1 
ATOM   1638 C CA  . VAL A 1 333 ? 104.227 116.707 125.818 1.00 80.58  ? 333 VAL A CA  1 
ATOM   1639 C C   . VAL A 1 333 ? 104.476 117.112 127.266 1.00 83.86  ? 333 VAL A C   1 
ATOM   1640 O O   . VAL A 1 333 ? 105.528 117.675 127.587 1.00 86.28  ? 333 VAL A O   1 
ATOM   1641 C CB  . VAL A 1 333 ? 103.680 117.877 124.981 1.00 83.63  ? 333 VAL A CB  1 
ATOM   1642 C CG1 . VAL A 1 333 ? 102.395 118.419 125.588 1.00 85.28  ? 333 VAL A CG1 1 
ATOM   1643 C CG2 . VAL A 1 333 ? 104.721 118.973 124.847 1.00 84.69  ? 333 VAL A CG2 1 
ATOM   1644 N N   . GLN A 1 334 ? 103.527 116.826 128.158 1.00 82.27  ? 334 GLN A N   1 
ATOM   1645 C CA  . GLN A 1 334 ? 103.697 117.165 129.567 1.00 80.67  ? 334 GLN A CA  1 
ATOM   1646 C C   . GLN A 1 334 ? 104.846 116.356 130.161 1.00 76.08  ? 334 GLN A C   1 
ATOM   1647 O O   . GLN A 1 334 ? 105.676 116.887 130.911 1.00 81.39  ? 334 GLN A O   1 
ATOM   1648 C CB  . GLN A 1 334 ? 102.359 116.921 130.283 1.00 78.31  ? 334 GLN A CB  1 
ATOM   1649 C CG  . GLN A 1 334 ? 101.990 117.737 131.549 1.00 79.02  ? 334 GLN A CG  1 
ATOM   1650 C CD  . GLN A 1 334 ? 102.970 117.715 132.704 1.00 84.87  ? 334 GLN A CD  1 
ATOM   1651 O OE1 . GLN A 1 334 ? 103.921 116.953 132.728 1.00 89.93  ? 334 GLN A OE1 1 
ATOM   1652 N NE2 . GLN A 1 334 ? 102.729 118.578 133.682 1.00 84.99  ? 334 GLN A NE2 1 
ATOM   1653 N N   . PHE A 1 335 ? 104.940 115.078 129.789 1.00 67.19  ? 335 PHE A N   1 
ATOM   1654 C CA  . PHE A 1 335 ? 106.052 114.249 130.241 1.00 65.32  ? 335 PHE A CA  1 
ATOM   1655 C C   . PHE A 1 335 ? 107.381 114.796 129.737 1.00 69.66  ? 335 PHE A C   1 
ATOM   1656 O O   . PHE A 1 335 ? 108.378 114.802 130.471 1.00 79.14  ? 335 PHE A O   1 
ATOM   1657 C CB  . PHE A 1 335 ? 105.835 112.805 129.784 1.00 65.67  ? 335 PHE A CB  1 
ATOM   1658 C CG  . PHE A 1 335 ? 106.930 111.853 130.188 1.00 65.12  ? 335 PHE A CG  1 
ATOM   1659 C CD1 . PHE A 1 335 ? 108.144 111.826 129.520 1.00 68.98  ? 335 PHE A CD1 1 
ATOM   1660 C CD2 . PHE A 1 335 ? 106.715 110.938 131.200 1.00 70.69  ? 335 PHE A CD2 1 
ATOM   1661 C CE1 . PHE A 1 335 ? 109.132 110.945 129.889 1.00 68.98  ? 335 PHE A CE1 1 
ATOM   1662 C CE2 . PHE A 1 335 ? 107.702 110.052 131.573 1.00 75.32  ? 335 PHE A CE2 1 
ATOM   1663 C CZ  . PHE A 1 335 ? 108.910 110.053 130.914 1.00 73.37  ? 335 PHE A CZ  1 
ATOM   1664 N N   . VAL A 1 336 ? 107.421 115.245 128.481 1.00 63.67  ? 336 VAL A N   1 
ATOM   1665 C CA  . VAL A 1 336 ? 108.645 115.834 127.946 1.00 61.05  ? 336 VAL A CA  1 
ATOM   1666 C C   . VAL A 1 336 ? 109.005 117.092 128.716 1.00 70.00  ? 336 VAL A C   1 
ATOM   1667 O O   . VAL A 1 336 ? 110.180 117.359 128.983 1.00 79.89  ? 336 VAL A O   1 
ATOM   1668 C CB  . VAL A 1 336 ? 108.496 116.119 126.443 1.00 65.02  ? 336 VAL A CB  1 
ATOM   1669 C CG1 . VAL A 1 336 ? 109.813 116.603 125.869 1.00 66.19  ? 336 VAL A CG1 1 
ATOM   1670 C CG2 . VAL A 1 336 ? 108.044 114.872 125.730 1.00 79.23  ? 336 VAL A CG2 1 
ATOM   1671 N N   . PHE A 1 337 ? 108.000 117.890 129.075 1.00 78.90  ? 337 PHE A N   1 
ATOM   1672 C CA  . PHE A 1 337 ? 108.260 119.088 129.863 1.00 80.22  ? 337 PHE A CA  1 
ATOM   1673 C C   . PHE A 1 337 ? 108.855 118.738 131.220 1.00 79.43  ? 337 PHE A C   1 
ATOM   1674 O O   . PHE A 1 337 ? 109.809 119.382 131.670 1.00 82.13  ? 337 PHE A O   1 
ATOM   1675 C CB  . PHE A 1 337 ? 106.974 119.893 130.033 1.00 76.78  ? 337 PHE A CB  1 
ATOM   1676 C CG  . PHE A 1 337 ? 107.093 121.019 131.013 1.00 74.66  ? 337 PHE A CG  1 
ATOM   1677 C CD1 . PHE A 1 337 ? 107.944 122.080 130.767 1.00 78.99  ? 337 PHE A CD1 1 
ATOM   1678 C CD2 . PHE A 1 337 ? 106.349 121.020 132.178 1.00 76.02  ? 337 PHE A CD2 1 
ATOM   1679 C CE1 . PHE A 1 337 ? 108.056 123.117 131.665 1.00 79.55  ? 337 PHE A CE1 1 
ATOM   1680 C CE2 . PHE A 1 337 ? 106.456 122.056 133.081 1.00 80.39  ? 337 PHE A CE2 1 
ATOM   1681 C CZ  . PHE A 1 337 ? 107.310 123.106 132.824 1.00 80.41  ? 337 PHE A CZ  1 
ATOM   1682 N N   . ASP A 1 338 ? 108.310 117.718 131.884 1.00 78.06  ? 338 ASP A N   1 
ATOM   1683 C CA  . ASP A 1 338 ? 108.851 117.315 133.181 1.00 70.39  ? 338 ASP A CA  1 
ATOM   1684 C C   . ASP A 1 338 ? 110.283 116.815 133.050 1.00 63.94  ? 338 ASP A C   1 
ATOM   1685 O O   . ASP A 1 338 ? 111.157 117.176 133.848 1.00 79.60  ? 338 ASP A O   1 
ATOM   1686 C CB  . ASP A 1 338 ? 107.972 116.241 133.819 1.00 77.79  ? 338 ASP A CB  1 
ATOM   1687 C CG  . ASP A 1 338 ? 106.607 116.758 134.198 1.00 84.36  ? 338 ASP A CG  1 
ATOM   1688 O OD1 . ASP A 1 338 ? 106.415 117.991 134.193 1.00 83.68  ? 338 ASP A OD1 1 
ATOM   1689 O OD2 . ASP A 1 338 ? 105.723 115.929 134.501 1.00 84.44  ? 338 ASP A OD2 1 
ATOM   1690 N N   . ALA A 1 339 ? 110.542 115.978 132.044 1.00 48.65  ? 339 ALA A N   1 
ATOM   1691 C CA  . ALA A 1 339 ? 111.890 115.457 131.853 1.00 53.26  ? 339 ALA A CA  1 
ATOM   1692 C C   . ALA A 1 339 ? 112.872 116.576 131.538 1.00 61.19  ? 339 ALA A C   1 
ATOM   1693 O O   . ALA A 1 339 ? 113.998 116.588 132.047 1.00 73.12  ? 339 ALA A O   1 
ATOM   1694 C CB  . ALA A 1 339 ? 111.894 114.408 130.743 1.00 61.35  ? 339 ALA A CB  1 
ATOM   1695 N N   . VAL A 1 340 ? 112.458 117.532 130.708 1.00 65.84  ? 340 VAL A N   1 
ATOM   1696 C CA  . VAL A 1 340 ? 113.328 118.644 130.352 1.00 64.69  ? 340 VAL A CA  1 
ATOM   1697 C C   . VAL A 1 340 ? 113.595 119.524 131.564 1.00 77.37  ? 340 VAL A C   1 
ATOM   1698 O O   . VAL A 1 340 ? 114.717 120.001 131.762 1.00 83.58  ? 340 VAL A O   1 
ATOM   1699 C CB  . VAL A 1 340 ? 112.711 119.439 129.189 1.00 68.61  ? 340 VAL A CB  1 
ATOM   1700 C CG1 . VAL A 1 340 ? 113.146 120.890 129.240 1.00 75.69  ? 340 VAL A CG1 1 
ATOM   1701 C CG2 . VAL A 1 340 ? 113.091 118.804 127.866 1.00 69.70  ? 340 VAL A CG2 1 
ATOM   1702 N N   . THR A 1 341 ? 112.576 119.753 132.396 1.00 81.31  ? 341 THR A N   1 
ATOM   1703 C CA  . THR A 1 341 ? 112.782 120.515 133.623 1.00 72.75  ? 341 THR A CA  1 
ATOM   1704 C C   . THR A 1 341 ? 113.774 119.813 134.538 1.00 70.42  ? 341 THR A C   1 
ATOM   1705 O O   . THR A 1 341 ? 114.652 120.455 135.130 1.00 73.31  ? 341 THR A O   1 
ATOM   1706 C CB  . THR A 1 341 ? 111.449 120.723 134.340 1.00 68.21  ? 341 THR A CB  1 
ATOM   1707 O OG1 . THR A 1 341 ? 110.563 121.468 133.498 1.00 73.86  ? 341 THR A OG1 1 
ATOM   1708 C CG2 . THR A 1 341 ? 111.655 121.479 135.639 1.00 69.60  ? 341 THR A CG2 1 
ATOM   1709 N N   . ASP A 1 342 ? 113.653 118.491 134.662 1.00 67.53  ? 342 ASP A N   1 
ATOM   1710 C CA  . ASP A 1 342 ? 114.583 117.743 135.499 1.00 58.98  ? 342 ASP A CA  1 
ATOM   1711 C C   . ASP A 1 342 ? 116.006 117.834 134.962 1.00 62.17  ? 342 ASP A C   1 
ATOM   1712 O O   . ASP A 1 342 ? 116.960 118.016 135.730 1.00 77.09  ? 342 ASP A O   1 
ATOM   1713 C CB  . ASP A 1 342 ? 114.137 116.289 135.595 1.00 64.69  ? 342 ASP A CB  1 
ATOM   1714 C CG  . ASP A 1 342 ? 114.362 115.708 136.965 1.00 77.62  ? 342 ASP A CG  1 
ATOM   1715 O OD1 . ASP A 1 342 ? 115.532 115.474 137.320 1.00 82.98  ? 342 ASP A OD1 1 
ATOM   1716 O OD2 . ASP A 1 342 ? 113.370 115.485 137.689 1.00 83.37  ? 342 ASP A OD2 1 
ATOM   1717 N N   . VAL A 1 343 ? 116.169 117.715 133.643 1.00 48.80  ? 343 VAL A N   1 
ATOM   1718 C CA  . VAL A 1 343 ? 117.501 117.808 133.052 1.00 52.08  ? 343 VAL A CA  1 
ATOM   1719 C C   . VAL A 1 343 ? 118.066 119.211 133.223 1.00 64.78  ? 343 VAL A C   1 
ATOM   1720 O O   . VAL A 1 343 ? 119.268 119.386 133.443 1.00 71.52  ? 343 VAL A O   1 
ATOM   1721 C CB  . VAL A 1 343 ? 117.465 117.390 131.572 1.00 65.84  ? 343 VAL A CB  1 
ATOM   1722 C CG1 . VAL A 1 343 ? 118.844 117.520 130.955 1.00 68.77  ? 343 VAL A CG1 1 
ATOM   1723 C CG2 . VAL A 1 343 ? 116.974 115.967 131.445 1.00 71.40  ? 343 VAL A CG2 1 
ATOM   1724 N N   . ILE A 1 344 ? 117.213 120.232 133.122 1.00 73.09  ? 344 ILE A N   1 
ATOM   1725 C CA  . ILE A 1 344 ? 117.661 121.605 133.328 1.00 68.08  ? 344 ILE A CA  1 
ATOM   1726 C C   . ILE A 1 344 ? 118.142 121.796 134.759 1.00 76.59  ? 344 ILE A C   1 
ATOM   1727 O O   . ILE A 1 344 ? 119.174 122.432 135.003 1.00 82.13  ? 344 ILE A O   1 
ATOM   1728 C CB  . ILE A 1 344 ? 116.535 122.591 132.968 1.00 60.99  ? 344 ILE A CB  1 
ATOM   1729 C CG1 . ILE A 1 344 ? 116.404 122.720 131.451 1.00 66.61  ? 344 ILE A CG1 1 
ATOM   1730 C CG2 . ILE A 1 344 ? 116.790 123.953 133.592 1.00 67.43  ? 344 ILE A CG2 1 
ATOM   1731 C CD1 . ILE A 1 344 ? 117.726 122.723 130.718 1.00 71.64  ? 344 ILE A CD1 1 
ATOM   1732 N N   . ILE A 1 345 ? 117.404 121.250 135.728 1.00 68.95  ? 345 ILE A N   1 
ATOM   1733 C CA  . ILE A 1 345 ? 117.817 121.355 137.125 1.00 52.20  ? 345 ILE A CA  1 
ATOM   1734 C C   . ILE A 1 345 ? 119.148 120.649 137.342 1.00 49.34  ? 345 ILE A C   1 
ATOM   1735 O O   . ILE A 1 345 ? 120.038 121.167 138.028 1.00 62.86  ? 345 ILE A O   1 
ATOM   1736 C CB  . ILE A 1 345 ? 116.723 120.797 138.050 1.00 52.17  ? 345 ILE A CB  1 
ATOM   1737 C CG1 . ILE A 1 345 ? 115.544 121.764 138.115 1.00 58.48  ? 345 ILE A CG1 1 
ATOM   1738 C CG2 . ILE A 1 345 ? 117.277 120.544 139.437 1.00 55.51  ? 345 ILE A CG2 1 
ATOM   1739 C CD1 . ILE A 1 345 ? 114.535 121.424 139.181 1.00 63.11  ? 345 ILE A CD1 1 
ATOM   1740 N N   . LYS A 1 346 ? 119.307 119.456 136.766 1.00 59.08  ? 346 LYS A N   1 
ATOM   1741 C CA  . LYS A 1 346 ? 120.566 118.731 136.917 1.00 59.67  ? 346 LYS A CA  1 
ATOM   1742 C C   . LYS A 1 346 ? 121.725 119.492 136.284 1.00 64.18  ? 346 LYS A C   1 
ATOM   1743 O O   . LYS A 1 346 ? 122.821 119.560 136.855 1.00 75.70  ? 346 LYS A O   1 
ATOM   1744 C CB  . LYS A 1 346 ? 120.444 117.338 136.306 1.00 64.16  ? 346 LYS A CB  1 
ATOM   1745 C CG  . LYS A 1 346 ? 121.202 116.267 137.059 1.00 66.48  ? 346 LYS A CG  1 
ATOM   1746 C CD  . LYS A 1 346 ? 120.944 114.897 136.464 1.00 69.19  ? 346 LYS A CD  1 
ATOM   1747 C CE  . LYS A 1 346 ? 121.535 114.789 135.071 1.00 69.96  ? 346 LYS A CE  1 
ATOM   1748 N NZ  . LYS A 1 346 ? 122.997 115.067 135.075 1.00 65.78  ? 346 LYS A NZ  1 
ATOM   1749 N N   . ASN A 1 347 ? 121.503 120.071 135.103 1.00 61.81  ? 347 ASN A N   1 
ATOM   1750 C CA  . ASN A 1 347 ? 122.552 120.840 134.444 1.00 64.88  ? 347 ASN A CA  1 
ATOM   1751 C C   . ASN A 1 347 ? 122.910 122.080 135.248 1.00 74.65  ? 347 ASN A C   1 
ATOM   1752 O O   . ASN A 1 347 ? 124.083 122.454 135.336 1.00 79.02  ? 347 ASN A O   1 
ATOM   1753 C CB  . ASN A 1 347 ? 122.112 121.224 133.033 1.00 71.44  ? 347 ASN A CB  1 
ATOM   1754 C CG  . ASN A 1 347 ? 122.412 120.145 132.019 1.00 77.76  ? 347 ASN A CG  1 
ATOM   1755 O OD1 . ASN A 1 347 ? 123.453 119.493 132.080 1.00 80.54  ? 347 ASN A OD1 1 
ATOM   1756 N ND2 . ASN A 1 347 ? 121.499 119.949 131.077 1.00 74.76  ? 347 ASN A ND2 1 
ATOM   1757 N N   . ASN A 1 348 ? 121.909 122.737 135.836 1.00 75.41  ? 348 ASN A N   1 
ATOM   1758 C CA  . ASN A 1 348 ? 122.182 123.888 136.688 1.00 68.09  ? 348 ASN A CA  1 
ATOM   1759 C C   . ASN A 1 348 ? 122.992 123.484 137.911 1.00 72.39  ? 348 ASN A C   1 
ATOM   1760 O O   . ASN A 1 348 ? 123.938 124.181 138.295 1.00 79.20  ? 348 ASN A O   1 
ATOM   1761 C CB  . ASN A 1 348 ? 120.871 124.551 137.104 1.00 67.43  ? 348 ASN A CB  1 
ATOM   1762 C CG  . ASN A 1 348 ? 120.235 125.335 135.979 1.00 77.23  ? 348 ASN A CG  1 
ATOM   1763 O OD1 . ASN A 1 348 ? 120.835 125.520 134.922 1.00 80.64  ? 348 ASN A OD1 1 
ATOM   1764 N ND2 . ASN A 1 348 ? 119.014 125.802 136.200 1.00 80.15  ? 348 ASN A ND2 1 
ATOM   1765 N N   . LEU A 1 349 ? 122.640 122.358 138.534 1.00 65.95  ? 349 LEU A N   1 
ATOM   1766 C CA  . LEU A 1 349 ? 123.403 121.880 139.682 1.00 56.76  ? 349 LEU A CA  1 
ATOM   1767 C C   . LEU A 1 349 ? 124.843 121.582 139.293 1.00 62.57  ? 349 LEU A C   1 
ATOM   1768 O O   . LEU A 1 349 ? 125.774 121.890 140.045 1.00 77.92  ? 349 LEU A O   1 
ATOM   1769 C CB  . LEU A 1 349 ? 122.745 120.637 140.277 1.00 52.47  ? 349 LEU A CB  1 
ATOM   1770 C CG  . LEU A 1 349 ? 121.443 120.836 141.046 1.00 57.01  ? 349 LEU A CG  1 
ATOM   1771 C CD1 . LEU A 1 349 ? 120.849 119.496 141.434 1.00 66.11  ? 349 LEU A CD1 1 
ATOM   1772 C CD2 . LEU A 1 349 ? 121.681 121.686 142.270 1.00 59.64  ? 349 LEU A CD2 1 
ATOM   1773 N N   . LYS A 1 350 ? 125.045 120.977 138.122 1.00 72.97  ? 350 LYS A N   1 
ATOM   1774 C CA  . LYS A 1 350 ? 126.401 120.715 137.654 1.00 75.33  ? 350 LYS A CA  1 
ATOM   1775 C C   . LYS A 1 350 ? 127.155 122.012 137.387 1.00 75.81  ? 350 LYS A C   1 
ATOM   1776 O O   . LYS A 1 350 ? 128.355 122.111 137.666 1.00 80.86  ? 350 LYS A O   1 
ATOM   1777 C CB  . LYS A 1 350 ? 126.365 119.846 136.398 1.00 80.66  ? 350 LYS A CB  1 
ATOM   1778 C CG  . LYS A 1 350 ? 127.733 119.381 135.932 1.00 81.41  ? 350 LYS A CG  1 
ATOM   1779 C CD  . LYS A 1 350 ? 127.919 117.893 136.170 1.00 82.95  ? 350 LYS A CD  1 
ATOM   1780 C CE  . LYS A 1 350 ? 129.391 117.518 136.180 1.00 78.94  ? 350 LYS A CE  1 
ATOM   1781 N NZ  . LYS A 1 350 ? 129.586 116.052 136.348 1.00 76.49  ? 350 LYS A NZ  1 
ATOM   1782 N N   . ASP A 1 351 ? 126.470 123.014 136.832 1.00 84.24  ? 351 ASP A N   1 
ATOM   1783 C CA  . ASP A 1 351 ? 127.114 124.294 136.557 1.00 88.70  ? 351 ASP A CA  1 
ATOM   1784 C C   . ASP A 1 351 ? 127.539 124.987 137.844 1.00 87.39  ? 351 ASP A C   1 
ATOM   1785 O O   . ASP A 1 351 ? 128.645 125.534 137.927 1.00 90.32  ? 351 ASP A O   1 
ATOM   1786 C CB  . ASP A 1 351 ? 126.174 125.190 135.751 1.00 91.99  ? 351 ASP A CB  1 
ATOM   1787 C CG  . ASP A 1 351 ? 126.500 125.194 134.272 1.00 94.19  ? 351 ASP A CG  1 
ATOM   1788 O OD1 . ASP A 1 351 ? 127.632 124.807 133.910 1.00 96.30  ? 351 ASP A OD1 1 
ATOM   1789 O OD2 . ASP A 1 351 ? 125.626 125.584 133.470 1.00 92.53  ? 351 ASP A OD2 1 
ATOM   1790 N N   . CYS A 1 352 ? 126.676 124.975 138.860 1.00 80.88  ? 352 CYS A N   1 
ATOM   1791 C CA  . CYS A 1 352 ? 127.041 125.542 140.152 1.00 78.50  ? 352 CYS A CA  1 
ATOM   1792 C C   . CYS A 1 352 ? 128.068 124.700 140.894 1.00 79.06  ? 352 CYS A C   1 
ATOM   1793 O O   . CYS A 1 352 ? 128.592 125.155 141.915 1.00 85.84  ? 352 CYS A O   1 
ATOM   1794 C CB  . CYS A 1 352 ? 125.799 125.726 141.024 1.00 78.39  ? 352 CYS A CB  1 
ATOM   1795 S SG  . CYS A 1 352 ? 124.395 126.498 140.201 1.00 95.24  ? 352 CYS A SG  1 
ATOM   1796 N N   . GLY A 1 353 ? 128.365 123.497 140.414 1.00 67.47  ? 353 GLY A N   1 
ATOM   1797 C CA  . GLY A 1 353 ? 129.354 122.649 141.037 1.00 65.25  ? 353 GLY A CA  1 
ATOM   1798 C C   . GLY A 1 353 ? 128.873 121.868 142.236 1.00 64.49  ? 353 GLY A C   1 
ATOM   1799 O O   . GLY A 1 353 ? 129.671 121.138 142.836 1.00 71.42  ? 353 GLY A O   1 
ATOM   1800 N N   . LEU A 1 354 ? 127.599 121.995 142.608 1.00 56.74  ? 354 LEU A N   1 
ATOM   1801 C CA  . LEU A 1 354 ? 127.088 121.253 143.755 1.00 57.90  ? 354 LEU A CA  1 
ATOM   1802 C C   . LEU A 1 354 ? 127.155 119.751 143.515 1.00 70.06  ? 354 LEU A C   1 
ATOM   1803 O O   . LEU A 1 354 ? 127.533 118.987 144.410 1.00 71.50  ? 354 LEU A O   1 
ATOM   1804 C CB  . LEU A 1 354 ? 125.655 121.680 144.058 1.00 57.99  ? 354 LEU A CB  1 
ATOM   1805 C CG  . LEU A 1 354 ? 125.483 123.086 144.625 1.00 64.54  ? 354 LEU A CG  1 
ATOM   1806 C CD1 . LEU A 1 354 ? 124.030 123.508 144.560 1.00 68.73  ? 354 LEU A CD1 1 
ATOM   1807 C CD2 . LEU A 1 354 ? 125.997 123.144 146.051 1.00 65.35  ? 354 LEU A CD2 1 
ATOM   1808 N N   . PHE A 1 355 ? 126.794 119.310 142.315 1.00 94.31  ? 355 PHE A N   1 
ATOM   1809 C CA  . PHE A 1 355 ? 126.801 117.892 141.986 1.00 94.62  ? 355 PHE A CA  1 
ATOM   1810 C C   . PHE A 1 355 ? 128.067 117.521 141.224 1.00 95.27  ? 355 PHE A C   1 
ATOM   1811 O O   . PHE A 1 355 ? 128.576 118.303 140.423 1.00 95.06  ? 355 PHE A O   1 
ATOM   1812 C CB  . PHE A 1 355 ? 125.556 117.530 141.171 1.00 89.25  ? 355 PHE A CB  1 
ATOM   1813 C CG  . PHE A 1 355 ? 125.746 116.354 140.260 1.00 87.91  ? 355 PHE A CG  1 
ATOM   1814 C CD1 . PHE A 1 355 ? 125.819 115.070 140.771 1.00 90.27  ? 355 PHE A CD1 1 
ATOM   1815 C CD2 . PHE A 1 355 ? 125.840 116.531 138.893 1.00 89.29  ? 355 PHE A CD2 1 
ATOM   1816 C CE1 . PHE A 1 355 ? 125.991 113.985 139.934 1.00 93.19  ? 355 PHE A CE1 1 
ATOM   1817 C CE2 . PHE A 1 355 ? 126.013 115.452 138.051 1.00 92.39  ? 355 PHE A CE2 1 
ATOM   1818 C CZ  . PHE A 1 355 ? 126.088 114.177 138.572 1.00 92.83  ? 355 PHE A CZ  1 
ATOM   1819 O OXT . PHE A 1 355 ? 128.614 116.432 141.395 1.00 94.93  ? 355 PHE A OXT 1 
ATOM   1820 N N   . GLU B 2 3   ? 127.459 86.450  84.528  1.00 147.22 ? 3   GLU B N   1 
ATOM   1821 C CA  . GLU B 2 3   ? 127.795 87.793  84.069  1.00 148.19 ? 3   GLU B CA  1 
ATOM   1822 C C   . GLU B 2 3   ? 128.351 88.637  85.209  1.00 148.79 ? 3   GLU B C   1 
ATOM   1823 O O   . GLU B 2 3   ? 129.427 89.221  85.088  1.00 148.86 ? 3   GLU B O   1 
ATOM   1824 C CB  . GLU B 2 3   ? 126.569 88.475  83.460  1.00 150.45 ? 3   GLU B CB  1 
ATOM   1825 C CG  . GLU B 2 3   ? 126.060 87.819  82.187  1.00 150.76 ? 3   GLU B CG  1 
ATOM   1826 C CD  . GLU B 2 3   ? 124.944 88.609  81.531  1.00 151.36 ? 3   GLU B CD  1 
ATOM   1827 O OE1 . GLU B 2 3   ? 124.568 89.671  82.071  1.00 151.23 ? 3   GLU B OE1 1 
ATOM   1828 O OE2 . GLU B 2 3   ? 124.443 88.168  80.476  1.00 151.48 ? 3   GLU B OE2 1 
ATOM   1829 N N   . LEU B 2 4   ? 127.609 88.691  86.318  1.00 149.86 ? 4   LEU B N   1 
ATOM   1830 C CA  . LEU B 2 4   ? 128.047 89.483  87.463  1.00 150.37 ? 4   LEU B CA  1 
ATOM   1831 C C   . LEU B 2 4   ? 129.381 88.982  88.000  1.00 149.96 ? 4   LEU B C   1 
ATOM   1832 O O   . LEU B 2 4   ? 130.263 89.781  88.336  1.00 148.70 ? 4   LEU B O   1 
ATOM   1833 C CB  . LEU B 2 4   ? 126.984 89.453  88.561  1.00 151.43 ? 4   LEU B CB  1 
ATOM   1834 C CG  . LEU B 2 4   ? 127.421 89.939  89.945  1.00 150.97 ? 4   LEU B CG  1 
ATOM   1835 C CD1 . LEU B 2 4   ? 127.742 91.426  89.919  1.00 149.12 ? 4   LEU B CD1 1 
ATOM   1836 C CD2 . LEU B 2 4   ? 126.352 89.635  90.984  1.00 150.02 ? 4   LEU B CD2 1 
ATOM   1837 N N   . ASP B 2 5   ? 129.545 87.662  88.088  1.00 151.67 ? 5   ASP B N   1 
ATOM   1838 C CA  . ASP B 2 5   ? 130.825 87.106  88.511  1.00 152.49 ? 5   ASP B CA  1 
ATOM   1839 C C   . ASP B 2 5   ? 131.934 87.483  87.538  1.00 152.83 ? 5   ASP B C   1 
ATOM   1840 O O   . ASP B 2 5   ? 133.035 87.859  87.956  1.00 151.82 ? 5   ASP B O   1 
ATOM   1841 C CB  . ASP B 2 5   ? 130.717 85.587  88.641  1.00 152.78 ? 5   ASP B CB  1 
ATOM   1842 C CG  . ASP B 2 5   ? 129.955 84.959  87.492  1.00 154.02 ? 5   ASP B CG  1 
ATOM   1843 O OD1 . ASP B 2 5   ? 129.462 85.711  86.625  1.00 154.54 ? 5   ASP B OD1 1 
ATOM   1844 O OD2 . ASP B 2 5   ? 129.849 83.715  87.455  1.00 153.60 ? 5   ASP B OD2 1 
ATOM   1845 N N   . GLN B 2 6   ? 131.660 87.395  86.234  1.00 153.33 ? 6   GLN B N   1 
ATOM   1846 C CA  . GLN B 2 6   ? 132.667 87.754  85.240  1.00 152.56 ? 6   GLN B CA  1 
ATOM   1847 C C   . GLN B 2 6   ? 133.016 89.235  85.315  1.00 151.46 ? 6   GLN B C   1 
ATOM   1848 O O   . GLN B 2 6   ? 134.193 89.610  85.232  1.00 149.39 ? 6   GLN B O   1 
ATOM   1849 C CB  . GLN B 2 6   ? 132.172 87.391  83.840  1.00 151.80 ? 6   GLN B CB  1 
ATOM   1850 C CG  . GLN B 2 6   ? 131.236 86.193  83.803  1.00 151.77 ? 6   GLN B CG  1 
ATOM   1851 C CD  . GLN B 2 6   ? 131.970 84.874  83.949  1.00 153.48 ? 6   GLN B CD  1 
ATOM   1852 O OE1 . GLN B 2 6   ? 133.198 84.821  83.884  1.00 153.53 ? 6   GLN B OE1 1 
ATOM   1853 N NE2 . GLN B 2 6   ? 131.217 83.798  84.148  1.00 152.55 ? 6   GLN B NE2 1 
ATOM   1854 N N   . LEU B 2 7   ? 132.005 90.094  85.465  1.00 145.81 ? 7   LEU B N   1 
ATOM   1855 C CA  . LEU B 2 7   ? 132.263 91.526  85.572  1.00 144.34 ? 7   LEU B CA  1 
ATOM   1856 C C   . LEU B 2 7   ? 133.077 91.846  86.818  1.00 143.33 ? 7   LEU B C   1 
ATOM   1857 O O   . LEU B 2 7   ? 134.007 92.657  86.767  1.00 143.01 ? 7   LEU B O   1 
ATOM   1858 C CB  . LEU B 2 7   ? 130.946 92.301  85.576  1.00 145.29 ? 7   LEU B CB  1 
ATOM   1859 C CG  . LEU B 2 7   ? 130.097 92.236  84.304  1.00 144.93 ? 7   LEU B CG  1 
ATOM   1860 C CD1 . LEU B 2 7   ? 128.707 92.798  84.556  1.00 143.71 ? 7   LEU B CD1 1 
ATOM   1861 C CD2 . LEU B 2 7   ? 130.775 92.973  83.161  1.00 143.82 ? 7   LEU B CD2 1 
ATOM   1862 N N   . ARG B 2 8   ? 132.745 91.218  87.947  1.00 144.66 ? 8   ARG B N   1 
ATOM   1863 C CA  . ARG B 2 8   ? 133.508 91.448  89.169  1.00 144.66 ? 8   ARG B CA  1 
ATOM   1864 C C   . ARG B 2 8   ? 134.944 90.960  89.022  1.00 146.17 ? 8   ARG B C   1 
ATOM   1865 O O   . ARG B 2 8   ? 135.886 91.630  89.463  1.00 146.30 ? 8   ARG B O   1 
ATOM   1866 C CB  . ARG B 2 8   ? 132.820 90.761  90.349  1.00 144.62 ? 8   ARG B CB  1 
ATOM   1867 C CG  . ARG B 2 8   ? 133.715 90.543  91.556  1.00 145.56 ? 8   ARG B CG  1 
ATOM   1868 C CD  . ARG B 2 8   ? 133.266 89.335  92.360  1.00 147.64 ? 8   ARG B CD  1 
ATOM   1869 N NE  . ARG B 2 8   ? 133.072 88.161  91.518  1.00 149.93 ? 8   ARG B NE  1 
ATOM   1870 C CZ  . ARG B 2 8   ? 133.757 87.032  91.636  1.00 148.70 ? 8   ARG B CZ  1 
ATOM   1871 N NH1 . ARG B 2 8   ? 134.696 86.886  92.557  1.00 147.27 ? 8   ARG B NH1 1 
ATOM   1872 N NH2 . ARG B 2 8   ? 133.494 86.023  90.811  1.00 147.74 ? 8   ARG B NH2 1 
ATOM   1873 N N   . GLN B 2 9   ? 135.132 89.795  88.396  1.00 148.16 ? 9   GLN B N   1 
ATOM   1874 C CA  . GLN B 2 9   ? 136.479 89.270  88.201  1.00 148.44 ? 9   GLN B CA  1 
ATOM   1875 C C   . GLN B 2 9   ? 137.304 90.186  87.308  1.00 147.61 ? 9   GLN B C   1 
ATOM   1876 O O   . GLN B 2 9   ? 138.476 90.452  87.594  1.00 146.82 ? 9   GLN B O   1 
ATOM   1877 C CB  . GLN B 2 9   ? 136.413 87.861  87.612  1.00 147.13 ? 9   GLN B CB  1 
ATOM   1878 C CG  . GLN B 2 9   ? 136.059 86.783  88.622  1.00 148.10 ? 9   GLN B CG  1 
ATOM   1879 C CD  . GLN B 2 9   ? 137.242 86.370  89.476  1.00 149.25 ? 9   GLN B CD  1 
ATOM   1880 O OE1 . GLN B 2 9   ? 138.373 86.798  89.241  1.00 149.35 ? 9   GLN B OE1 1 
ATOM   1881 N NE2 . GLN B 2 9   ? 136.987 85.532  90.474  1.00 148.27 ? 9   GLN B NE2 1 
ATOM   1882 N N   . GLU B 2 10  ? 136.710 90.690  86.224  1.00 140.66 ? 10  GLU B N   1 
ATOM   1883 C CA  . GLU B 2 10  ? 137.466 91.580  85.349  1.00 140.24 ? 10  GLU B CA  1 
ATOM   1884 C C   . GLU B 2 10  ? 137.711 92.935  86.004  1.00 138.96 ? 10  GLU B C   1 
ATOM   1885 O O   . GLU B 2 10  ? 138.752 93.553  85.765  1.00 138.02 ? 10  GLU B O   1 
ATOM   1886 C CB  . GLU B 2 10  ? 136.758 91.734  84.002  1.00 139.84 ? 10  GLU B CB  1 
ATOM   1887 C CG  . GLU B 2 10  ? 135.517 92.600  84.012  1.00 139.70 ? 10  GLU B CG  1 
ATOM   1888 C CD  . GLU B 2 10  ? 134.900 92.735  82.636  1.00 142.53 ? 10  GLU B CD  1 
ATOM   1889 O OE1 . GLU B 2 10  ? 135.425 92.117  81.686  1.00 142.81 ? 10  GLU B OE1 1 
ATOM   1890 O OE2 . GLU B 2 10  ? 133.893 93.459  82.501  1.00 143.34 ? 10  GLU B OE2 1 
ATOM   1891 N N   . ALA B 2 11  ? 136.785 93.406  86.842  1.00 136.95 ? 11  ALA B N   1 
ATOM   1892 C CA  . ALA B 2 11  ? 137.040 94.625  87.600  1.00 137.65 ? 11  ALA B CA  1 
ATOM   1893 C C   . ALA B 2 11  ? 138.217 94.436  88.544  1.00 136.58 ? 11  ALA B C   1 
ATOM   1894 O O   . ALA B 2 11  ? 139.079 95.315  88.663  1.00 136.21 ? 11  ALA B O   1 
ATOM   1895 C CB  . ALA B 2 11  ? 135.788 95.036  88.373  1.00 137.41 ? 11  ALA B CB  1 
ATOM   1896 N N   . GLU B 2 12  ? 138.274 93.285  89.217  1.00 138.20 ? 12  GLU B N   1 
ATOM   1897 C CA  . GLU B 2 12  ? 139.431 92.971  90.045  1.00 138.36 ? 12  GLU B CA  1 
ATOM   1898 C C   . GLU B 2 12  ? 140.699 92.878  89.208  1.00 137.89 ? 12  GLU B C   1 
ATOM   1899 O O   . GLU B 2 12  ? 141.776 93.269  89.668  1.00 136.15 ? 12  GLU B O   1 
ATOM   1900 C CB  . GLU B 2 12  ? 139.190 91.666  90.806  1.00 140.18 ? 12  GLU B CB  1 
ATOM   1901 C CG  . GLU B 2 12  ? 140.392 91.158  91.589  1.00 141.87 ? 12  GLU B CG  1 
ATOM   1902 C CD  . GLU B 2 12  ? 141.149 90.068  90.855  1.00 143.01 ? 12  GLU B CD  1 
ATOM   1903 O OE1 . GLU B 2 12  ? 140.719 89.687  89.746  1.00 143.01 ? 12  GLU B OE1 1 
ATOM   1904 O OE2 . GLU B 2 12  ? 142.173 89.591  91.388  1.00 143.35 ? 12  GLU B OE2 1 
ATOM   1905 N N   . GLN B 2 13  ? 140.591 92.371  87.979  1.00 137.56 ? 13  GLN B N   1 
ATOM   1906 C CA  . GLN B 2 13  ? 141.759 92.276  87.107  1.00 139.93 ? 13  GLN B CA  1 
ATOM   1907 C C   . GLN B 2 13  ? 142.289 93.660  86.744  1.00 141.12 ? 13  GLN B C   1 
ATOM   1908 O O   . GLN B 2 13  ? 143.501 93.901  86.772  1.00 139.92 ? 13  GLN B O   1 
ATOM   1909 C CB  . GLN B 2 13  ? 141.406 91.475  85.851  1.00 141.49 ? 13  GLN B CB  1 
ATOM   1910 C CG  . GLN B 2 13  ? 142.027 91.988  84.558  1.00 142.82 ? 13  GLN B CG  1 
ATOM   1911 C CD  . GLN B 2 13  ? 143.528 91.772  84.499  1.00 144.14 ? 13  GLN B CD  1 
ATOM   1912 O OE1 . GLN B 2 13  ? 144.035 90.735  84.929  1.00 143.33 ? 13  GLN B OE1 1 
ATOM   1913 N NE2 . GLN B 2 13  ? 144.247 92.753  83.967  1.00 141.92 ? 13  GLN B NE2 1 
ATOM   1914 N N   . LEU B 2 14  ? 141.393 94.586  86.394  1.00 131.68 ? 14  LEU B N   1 
ATOM   1915 C CA  . LEU B 2 14  ? 141.829 95.953  86.111  1.00 128.76 ? 14  LEU B CA  1 
ATOM   1916 C C   . LEU B 2 14  ? 142.387 96.633  87.355  1.00 127.44 ? 14  LEU B C   1 
ATOM   1917 O O   . LEU B 2 14  ? 143.358 97.394  87.266  1.00 129.24 ? 14  LEU B O   1 
ATOM   1918 C CB  . LEU B 2 14  ? 140.692 96.777  85.505  1.00 129.96 ? 14  LEU B CB  1 
ATOM   1919 C CG  . LEU B 2 14  ? 140.165 96.360  84.126  1.00 131.83 ? 14  LEU B CG  1 
ATOM   1920 C CD1 . LEU B 2 14  ? 138.949 97.201  83.765  1.00 130.45 ? 14  LEU B CD1 1 
ATOM   1921 C CD2 . LEU B 2 14  ? 141.205 96.438  83.027  1.00 131.45 ? 14  LEU B CD2 1 
ATOM   1922 N N   . LYS B 2 15  ? 141.785 96.385  88.520  1.00 124.75 ? 15  LYS B N   1 
ATOM   1923 C CA  . LYS B 2 15  ? 142.344 96.926  89.755  1.00 126.77 ? 15  LYS B CA  1 
ATOM   1924 C C   . LYS B 2 15  ? 143.752 96.396  89.991  1.00 126.77 ? 15  LYS B C   1 
ATOM   1925 O O   . LYS B 2 15  ? 144.652 97.144  90.392  1.00 128.65 ? 15  LYS B O   1 
ATOM   1926 C CB  . LYS B 2 15  ? 141.437 96.589  90.937  1.00 126.23 ? 15  LYS B CB  1 
ATOM   1927 C CG  . LYS B 2 15  ? 141.487 97.608  92.061  1.00 126.02 ? 15  LYS B CG  1 
ATOM   1928 C CD  . LYS B 2 15  ? 140.380 97.374  93.075  1.00 127.00 ? 15  LYS B CD  1 
ATOM   1929 C CE  . LYS B 2 15  ? 139.031 97.198  92.398  1.00 126.28 ? 15  LYS B CE  1 
ATOM   1930 N NZ  . LYS B 2 15  ? 137.965 96.861  93.381  1.00 126.30 ? 15  LYS B NZ  1 
ATOM   1931 N N   . ASN B 2 16  ? 143.963 95.106  89.731  1.00 123.80 ? 16  ASN B N   1 
ATOM   1932 C CA  . ASN B 2 16  ? 145.291 94.523  89.862  1.00 124.79 ? 16  ASN B CA  1 
ATOM   1933 C C   . ASN B 2 16  ? 146.264 95.157  88.876  1.00 126.06 ? 16  ASN B C   1 
ATOM   1934 O O   . ASN B 2 16  ? 147.421 95.430  89.218  1.00 126.21 ? 16  ASN B O   1 
ATOM   1935 C CB  . ASN B 2 16  ? 145.210 93.013  89.643  1.00 125.47 ? 16  ASN B CB  1 
ATOM   1936 C CG  . ASN B 2 16  ? 145.517 92.227  90.898  1.00 127.85 ? 16  ASN B CG  1 
ATOM   1937 O OD1 . ASN B 2 16  ? 145.602 92.789  91.989  1.00 128.17 ? 16  ASN B OD1 1 
ATOM   1938 N ND2 . ASN B 2 16  ? 145.692 90.919  90.750  1.00 127.99 ? 16  ASN B ND2 1 
ATOM   1939 N N   . GLN B 2 17  ? 145.808 95.397  87.644  1.00 123.38 ? 17  GLN B N   1 
ATOM   1940 C CA  . GLN B 2 17  ? 146.668 96.011  86.637  1.00 124.42 ? 17  GLN B CA  1 
ATOM   1941 C C   . GLN B 2 17  ? 147.087 97.415  87.051  1.00 120.37 ? 17  GLN B C   1 
ATOM   1942 O O   . GLN B 2 17  ? 148.258 97.791  86.912  1.00 117.22 ? 17  GLN B O   1 
ATOM   1943 C CB  . GLN B 2 17  ? 145.953 96.038  85.284  1.00 122.89 ? 17  GLN B CB  1 
ATOM   1944 C CG  . GLN B 2 17  ? 146.278 97.252  84.424  1.00 122.37 ? 17  GLN B CG  1 
ATOM   1945 C CD  . GLN B 2 17  ? 146.132 96.972  82.941  1.00 124.98 ? 17  GLN B CD  1 
ATOM   1946 O OE1 . GLN B 2 17  ? 145.536 95.972  82.542  1.00 125.39 ? 17  GLN B OE1 1 
ATOM   1947 N NE2 . GLN B 2 17  ? 146.682 97.854  82.115  1.00 123.24 ? 17  GLN B NE2 1 
ATOM   1948 N N   . ILE B 2 18  ? 146.146 98.207  87.570  1.00 116.28 ? 18  ILE B N   1 
ATOM   1949 C CA  . ILE B 2 18  ? 146.505 99.556  87.993  1.00 114.32 ? 18  ILE B CA  1 
ATOM   1950 C C   . ILE B 2 18  ? 147.388 99.514  89.234  1.00 114.83 ? 18  ILE B C   1 
ATOM   1951 O O   . ILE B 2 18  ? 148.258 100.376 89.409  1.00 117.33 ? 18  ILE B O   1 
ATOM   1952 C CB  . ILE B 2 18  ? 145.240 100.429 88.165  1.00 115.37 ? 18  ILE B CB  1 
ATOM   1953 C CG1 . ILE B 2 18  ? 144.431 100.106 89.433  1.00 116.67 ? 18  ILE B CG1 1 
ATOM   1954 C CG2 . ILE B 2 18  ? 144.371 100.353 86.914  1.00 116.00 ? 18  ILE B CG2 1 
ATOM   1955 C CD1 . ILE B 2 18  ? 144.913 100.758 90.729  1.00 116.36 ? 18  ILE B CD1 1 
ATOM   1956 N N   . ARG B 2 19  ? 147.204 98.517  90.104  1.00 124.83 ? 19  ARG B N   1 
ATOM   1957 C CA  . ARG B 2 19  ? 148.111 98.376  91.239  1.00 126.23 ? 19  ARG B CA  1 
ATOM   1958 C C   . ARG B 2 19  ? 149.523 98.093  90.746  1.00 125.92 ? 19  ARG B C   1 
ATOM   1959 O O   . ARG B 2 19  ? 150.496 98.653  91.264  1.00 124.64 ? 19  ARG B O   1 
ATOM   1960 C CB  . ARG B 2 19  ? 147.619 97.266  92.179  1.00 125.44 ? 19  ARG B CB  1 
ATOM   1961 C CG  . ARG B 2 19  ? 148.596 96.798  93.290  1.00 124.98 ? 19  ARG B CG  1 
ATOM   1962 C CD  . ARG B 2 19  ? 149.744 95.842  92.891  1.00 126.82 ? 19  ARG B CD  1 
ATOM   1963 N NE  . ARG B 2 19  ? 149.473 94.861  91.842  1.00 131.59 ? 19  ARG B NE  1 
ATOM   1964 C CZ  . ARG B 2 19  ? 148.433 94.037  91.787  1.00 131.10 ? 19  ARG B CZ  1 
ATOM   1965 N NH1 . ARG B 2 19  ? 147.517 94.002  92.743  1.00 129.28 ? 19  ARG B NH1 1 
ATOM   1966 N NH2 . ARG B 2 19  ? 148.327 93.202  90.758  1.00 130.11 ? 19  ARG B NH2 1 
ATOM   1967 N N   . ASP B 2 20  ? 149.649 97.221  89.742  1.00 122.39 ? 20  ASP B N   1 
ATOM   1968 C CA  . ASP B 2 20  ? 150.960 96.927  89.172  1.00 123.53 ? 20  ASP B CA  1 
ATOM   1969 C C   . ASP B 2 20  ? 151.574 98.166  88.536  1.00 124.81 ? 20  ASP B C   1 
ATOM   1970 O O   . ASP B 2 20  ? 152.779 98.403  88.660  1.00 125.31 ? 20  ASP B O   1 
ATOM   1971 C CB  . ASP B 2 20  ? 150.857 95.804  88.141  1.00 125.41 ? 20  ASP B CB  1 
ATOM   1972 C CG  . ASP B 2 20  ? 150.345 94.509  88.734  1.00 128.51 ? 20  ASP B CG  1 
ATOM   1973 O OD1 . ASP B 2 20  ? 150.853 94.098  89.798  1.00 128.81 ? 20  ASP B OD1 1 
ATOM   1974 O OD2 . ASP B 2 20  ? 149.450 93.890  88.122  1.00 130.04 ? 20  ASP B OD2 1 
ATOM   1975 N N   . ALA B 2 21  ? 150.763 98.957  87.833  1.00 117.10 ? 21  ALA B N   1 
ATOM   1976 C CA  . ALA B 2 21  ? 151.276 100.184 87.231  1.00 116.57 ? 21  ALA B CA  1 
ATOM   1977 C C   . ALA B 2 21  ? 151.776 101.149 88.298  1.00 112.18 ? 21  ALA B C   1 
ATOM   1978 O O   . ALA B 2 21  ? 152.849 101.749 88.154  1.00 112.57 ? 21  ALA B O   1 
ATOM   1979 C CB  . ALA B 2 21  ? 150.196 100.841 86.373  1.00 116.68 ? 21  ALA B CB  1 
ATOM   1980 N N   . ARG B 2 22  ? 151.013 101.304 89.383  1.00 104.63 ? 22  ARG B N   1 
ATOM   1981 C CA  . ARG B 2 22  ? 151.437 102.177 90.471  1.00 106.78 ? 22  ARG B CA  1 
ATOM   1982 C C   . ARG B 2 22  ? 152.728 101.679 91.105  1.00 109.08 ? 22  ARG B C   1 
ATOM   1983 O O   . ARG B 2 22  ? 153.622 102.474 91.418  1.00 112.01 ? 22  ARG B O   1 
ATOM   1984 C CB  . ARG B 2 22  ? 150.332 102.280 91.521  1.00 106.60 ? 22  ARG B CB  1 
ATOM   1985 C CG  . ARG B 2 22  ? 149.113 103.055 91.062  1.00 107.29 ? 22  ARG B CG  1 
ATOM   1986 C CD  . ARG B 2 22  ? 148.004 103.000 92.095  1.00 107.44 ? 22  ARG B CD  1 
ATOM   1987 N NE  . ARG B 2 22  ? 146.816 103.715 91.648  1.00 107.19 ? 22  ARG B NE  1 
ATOM   1988 C CZ  . ARG B 2 22  ? 145.740 103.919 92.395  1.00 107.39 ? 22  ARG B CZ  1 
ATOM   1989 N NH1 . ARG B 2 22  ? 145.666 103.469 93.636  1.00 108.42 ? 22  ARG B NH1 1 
ATOM   1990 N NH2 . ARG B 2 22  ? 144.713 104.591 91.884  1.00 105.86 ? 22  ARG B NH2 1 
ATOM   1991 N N   . LYS B 2 23  ? 152.841 100.365 91.306  1.00 114.85 ? 23  LYS B N   1 
ATOM   1992 C CA  . LYS B 2 23  ? 154.063 99.803  91.871  1.00 117.33 ? 23  LYS B CA  1 
ATOM   1993 C C   . LYS B 2 23  ? 155.252 100.034 90.947  1.00 117.21 ? 23  LYS B C   1 
ATOM   1994 O O   . LYS B 2 23  ? 156.350 100.369 91.407  1.00 117.85 ? 23  LYS B O   1 
ATOM   1995 C CB  . LYS B 2 23  ? 153.873 98.310  92.142  1.00 119.18 ? 23  LYS B CB  1 
ATOM   1996 C CG  . LYS B 2 23  ? 155.166 97.524  92.278  1.00 118.21 ? 23  LYS B CG  1 
ATOM   1997 C CD  . LYS B 2 23  ? 155.920 97.905  93.540  1.00 119.33 ? 23  LYS B CD  1 
ATOM   1998 C CE  . LYS B 2 23  ? 157.420 97.773  93.343  1.00 118.58 ? 23  LYS B CE  1 
ATOM   1999 N NZ  . LYS B 2 23  ? 157.944 98.780  92.380  1.00 120.01 ? 23  LYS B NZ  1 
ATOM   2000 N N   . ALA B 2 24  ? 155.051 99.859  89.640  1.00 116.81 ? 24  ALA B N   1 
ATOM   2001 C CA  . ALA B 2 24  ? 156.135 100.064 88.687  1.00 120.14 ? 24  ALA B CA  1 
ATOM   2002 C C   . ALA B 2 24  ? 156.584 101.518 88.667  1.00 119.20 ? 24  ALA B C   1 
ATOM   2003 O O   . ALA B 2 24  ? 157.785 101.803 88.589  1.00 119.53 ? 24  ALA B O   1 
ATOM   2004 C CB  . ALA B 2 24  ? 155.698 99.618  87.292  1.00 119.28 ? 24  ALA B CB  1 
ATOM   2005 N N   . CYS B 2 25  ? 155.637 102.453 88.736  1.00 121.14 ? 25  CYS B N   1 
ATOM   2006 C CA  . CYS B 2 25  ? 155.998 103.865 88.720  1.00 122.53 ? 25  CYS B CA  1 
ATOM   2007 C C   . CYS B 2 25  ? 156.596 104.341 90.038  1.00 122.36 ? 25  CYS B C   1 
ATOM   2008 O O   . CYS B 2 25  ? 157.138 105.450 90.083  1.00 122.86 ? 25  CYS B O   1 
ATOM   2009 C CB  . CYS B 2 25  ? 154.777 104.713 88.369  1.00 123.79 ? 25  CYS B CB  1 
ATOM   2010 S SG  . CYS B 2 25  ? 154.065 104.330 86.754  1.00 128.66 ? 25  CYS B SG  1 
ATOM   2011 N N   . ALA B 2 26  ? 156.517 103.542 91.100  1.00 111.69 ? 26  ALA B N   1 
ATOM   2012 C CA  . ALA B 2 26  ? 157.052 103.933 92.404  1.00 110.58 ? 26  ALA B CA  1 
ATOM   2013 C C   . ALA B 2 26  ? 158.498 103.456 92.557  1.00 109.95 ? 26  ALA B C   1 
ATOM   2014 O O   . ALA B 2 26  ? 158.832 102.638 93.412  1.00 111.08 ? 26  ALA B O   1 
ATOM   2015 C CB  . ALA B 2 26  ? 156.168 103.391 93.520  1.00 108.77 ? 26  ALA B CB  1 
ATOM   2016 N N   . ASP B 2 27  ? 159.364 103.992 91.694  1.00 116.82 ? 27  ASP B N   1 
ATOM   2017 C CA  . ASP B 2 27  ? 160.772 103.609 91.729  1.00 118.86 ? 27  ASP B CA  1 
ATOM   2018 C C   . ASP B 2 27  ? 161.437 104.050 93.028  1.00 117.95 ? 27  ASP B C   1 
ATOM   2019 O O   . ASP B 2 27  ? 162.232 103.303 93.609  1.00 118.81 ? 27  ASP B O   1 
ATOM   2020 C CB  . ASP B 2 27  ? 161.507 104.192 90.523  1.00 119.95 ? 27  ASP B CB  1 
ATOM   2021 C CG  . ASP B 2 27  ? 161.413 105.701 90.457  1.00 121.82 ? 27  ASP B CG  1 
ATOM   2022 O OD1 . ASP B 2 27  ? 160.284 106.230 90.506  1.00 122.34 ? 27  ASP B OD1 1 
ATOM   2023 O OD2 . ASP B 2 27  ? 162.470 106.359 90.357  1.00 120.53 ? 27  ASP B OD2 1 
ATOM   2024 N N   . ALA B 2 28  ? 161.127 105.257 93.497  1.00 111.72 ? 28  ALA B N   1 
ATOM   2025 C CA  . ALA B 2 28  ? 161.686 105.764 94.742  1.00 111.97 ? 28  ALA B CA  1 
ATOM   2026 C C   . ALA B 2 28  ? 160.756 106.838 95.280  1.00 114.00 ? 28  ALA B C   1 
ATOM   2027 O O   . ALA B 2 28  ? 160.443 107.796 94.568  1.00 116.16 ? 28  ALA B O   1 
ATOM   2028 C CB  . ALA B 2 28  ? 163.095 106.328 94.531  1.00 111.16 ? 28  ALA B CB  1 
ATOM   2029 N N   . THR B 2 29  ? 160.330 106.683 96.531  1.00 114.96 ? 29  THR B N   1 
ATOM   2030 C CA  . THR B 2 29  ? 159.330 107.571 97.103  1.00 117.43 ? 29  THR B CA  1 
ATOM   2031 C C   . THR B 2 29  ? 159.920 108.958 97.357  1.00 117.08 ? 29  THR B C   1 
ATOM   2032 O O   . THR B 2 29  ? 161.095 109.231 97.096  1.00 117.74 ? 29  THR B O   1 
ATOM   2033 C CB  . THR B 2 29  ? 158.769 106.980 98.394  1.00 116.59 ? 29  THR B CB  1 
ATOM   2034 O OG1 . THR B 2 29  ? 159.837 106.755 99.322  1.00 117.09 ? 29  THR B OG1 1 
ATOM   2035 C CG2 . THR B 2 29  ? 158.062 105.663 98.112  1.00 114.20 ? 29  THR B CG2 1 
ATOM   2036 N N   . LEU B 2 30  ? 159.073 109.851 97.873  1.00 103.52 ? 30  LEU B N   1 
ATOM   2037 C CA  . LEU B 2 30  ? 159.499 111.210 98.183  1.00 102.16 ? 30  LEU B CA  1 
ATOM   2038 C C   . LEU B 2 30  ? 160.428 111.262 99.388  1.00 100.13 ? 30  LEU B C   1 
ATOM   2039 O O   . LEU B 2 30  ? 161.141 112.255 99.564  1.00 102.18 ? 30  LEU B O   1 
ATOM   2040 C CB  . LEU B 2 30  ? 158.264 112.090 98.410  1.00 101.94 ? 30  LEU B CB  1 
ATOM   2041 C CG  . LEU B 2 30  ? 158.396 113.562 98.805  1.00 102.59 ? 30  LEU B CG  1 
ATOM   2042 C CD1 . LEU B 2 30  ? 159.203 114.328 97.784  1.00 103.83 ? 30  LEU B CD1 1 
ATOM   2043 C CD2 . LEU B 2 30  ? 157.023 114.190 98.952  1.00 101.38 ? 30  LEU B CD2 1 
ATOM   2044 N N   . SER B 2 31  ? 160.449 110.212 100.211 1.00 100.46 ? 31  SER B N   1 
ATOM   2045 C CA  . SER B 2 31  ? 161.260 110.236 101.423 1.00 102.98 ? 31  SER B CA  1 
ATOM   2046 C C   . SER B 2 31  ? 162.749 110.262 101.100 1.00 104.55 ? 31  SER B C   1 
ATOM   2047 O O   . SER B 2 31  ? 163.491 111.101 101.624 1.00 108.16 ? 31  SER B O   1 
ATOM   2048 C CB  . SER B 2 31  ? 160.920 109.033 102.302 1.00 105.41 ? 31  SER B CB  1 
ATOM   2049 O OG  . SER B 2 31  ? 161.733 109.006 103.461 1.00 107.57 ? 31  SER B OG  1 
ATOM   2050 N N   . GLN B 2 32  ? 163.209 109.350 100.239 1.00 106.26 ? 32  GLN B N   1 
ATOM   2051 C CA  . GLN B 2 32  ? 164.636 109.291 99.936  1.00 109.78 ? 32  GLN B CA  1 
ATOM   2052 C C   . GLN B 2 32  ? 165.102 110.495 99.127  1.00 110.06 ? 32  GLN B C   1 
ATOM   2053 O O   . GLN B 2 32  ? 166.232 110.960 99.312  1.00 109.86 ? 32  GLN B O   1 
ATOM   2054 C CB  . GLN B 2 32  ? 164.986 107.994 99.201  1.00 108.02 ? 32  GLN B CB  1 
ATOM   2055 C CG  . GLN B 2 32  ? 164.182 106.768 99.608  1.00 106.40 ? 32  GLN B CG  1 
ATOM   2056 C CD  . GLN B 2 32  ? 162.854 106.663 98.892  1.00 110.57 ? 32  GLN B CD  1 
ATOM   2057 O OE1 . GLN B 2 32  ? 161.984 107.516 99.052  1.00 111.86 ? 32  GLN B OE1 1 
ATOM   2058 N NE2 . GLN B 2 32  ? 162.691 105.614 98.095  1.00 108.25 ? 32  GLN B NE2 1 
ATOM   2059 N N   . ILE B 2 33  ? 164.260 111.013 98.229  1.00 106.89 ? 33  ILE B N   1 
ATOM   2060 C CA  . ILE B 2 33  ? 164.678 112.135 97.398  1.00 108.50 ? 33  ILE B CA  1 
ATOM   2061 C C   . ILE B 2 33  ? 164.841 113.413 98.215  1.00 109.51 ? 33  ILE B C   1 
ATOM   2062 O O   . ILE B 2 33  ? 165.523 114.344 97.771  1.00 108.42 ? 33  ILE B O   1 
ATOM   2063 C CB  . ILE B 2 33  ? 163.688 112.337 96.235  1.00 107.81 ? 33  ILE B CB  1 
ATOM   2064 C CG1 . ILE B 2 33  ? 164.326 113.166 95.116  1.00 108.22 ? 33  ILE B CG1 1 
ATOM   2065 C CG2 . ILE B 2 33  ? 162.417 112.999 96.720  1.00 107.83 ? 33  ILE B CG2 1 
ATOM   2066 C CD1 . ILE B 2 33  ? 165.748 112.771 94.793  1.00 106.17 ? 33  ILE B CD1 1 
ATOM   2067 N N   . THR B 2 34  ? 164.242 113.483 99.404  1.00 115.11 ? 34  THR B N   1 
ATOM   2068 C CA  . THR B 2 34  ? 164.400 114.620 100.304 1.00 115.77 ? 34  THR B CA  1 
ATOM   2069 C C   . THR B 2 34  ? 165.218 114.258 101.540 1.00 112.47 ? 34  THR B C   1 
ATOM   2070 O O   . THR B 2 34  ? 165.061 114.873 102.597 1.00 111.89 ? 34  THR B O   1 
ATOM   2071 C CB  . THR B 2 34  ? 163.041 115.177 100.724 1.00 114.76 ? 34  THR B CB  1 
ATOM   2072 O OG1 . THR B 2 34  ? 162.409 114.268 101.633 1.00 113.94 ? 34  THR B OG1 1 
ATOM   2073 C CG2 . THR B 2 34  ? 162.152 115.385 99.514  1.00 112.28 ? 34  THR B CG2 1 
ATOM   2074 N N   . ASN B 2 35  ? 166.086 113.251 101.424 1.00 114.07 ? 35  ASN B N   1 
ATOM   2075 C CA  . ASN B 2 35  ? 166.899 112.843 102.564 1.00 115.48 ? 35  ASN B CA  1 
ATOM   2076 C C   . ASN B 2 35  ? 167.869 113.944 102.976 1.00 118.65 ? 35  ASN B C   1 
ATOM   2077 O O   . ASN B 2 35  ? 168.062 114.193 104.171 1.00 120.04 ? 35  ASN B O   1 
ATOM   2078 C CB  . ASN B 2 35  ? 167.641 111.546 102.234 1.00 117.80 ? 35  ASN B CB  1 
ATOM   2079 C CG  . ASN B 2 35  ? 168.928 111.380 103.026 1.00 120.63 ? 35  ASN B CG  1 
ATOM   2080 O OD1 . ASN B 2 35  ? 169.946 112.009 102.730 1.00 121.53 ? 35  ASN B OD1 1 
ATOM   2081 N ND2 . ASN B 2 35  ? 168.886 110.529 104.044 1.00 120.26 ? 35  ASN B ND2 1 
ATOM   2082 N N   . ASN B 2 36  ? 168.488 114.611 102.006 1.00 116.99 ? 36  ASN B N   1 
ATOM   2083 C CA  . ASN B 2 36  ? 169.477 115.645 102.279 1.00 116.55 ? 36  ASN B CA  1 
ATOM   2084 C C   . ASN B 2 36  ? 168.896 117.055 102.253 1.00 118.59 ? 36  ASN B C   1 
ATOM   2085 O O   . ASN B 2 36  ? 169.653 118.025 102.360 1.00 120.61 ? 36  ASN B O   1 
ATOM   2086 C CB  . ASN B 2 36  ? 170.647 115.525 101.295 1.00 115.88 ? 36  ASN B CB  1 
ATOM   2087 C CG  . ASN B 2 36  ? 170.352 116.143 99.936  1.00 119.97 ? 36  ASN B CG  1 
ATOM   2088 O OD1 . ASN B 2 36  ? 169.198 116.324 99.551  1.00 121.35 ? 36  ASN B OD1 1 
ATOM   2089 N ND2 . ASN B 2 36  ? 171.409 116.471 99.202  1.00 119.24 ? 36  ASN B ND2 1 
ATOM   2090 N N   . ILE B 2 37  ? 167.577 117.190 102.109 1.00 111.81 ? 37  ILE B N   1 
ATOM   2091 C CA  . ILE B 2 37  ? 166.950 118.506 102.107 1.00 112.20 ? 37  ILE B CA  1 
ATOM   2092 C C   . ILE B 2 37  ? 167.075 119.136 103.488 1.00 112.79 ? 37  ILE B C   1 
ATOM   2093 O O   . ILE B 2 37  ? 166.928 118.462 104.516 1.00 114.46 ? 37  ILE B O   1 
ATOM   2094 C CB  . ILE B 2 37  ? 165.480 118.399 101.660 1.00 111.29 ? 37  ILE B CB  1 
ATOM   2095 C CG1 . ILE B 2 37  ? 165.350 118.561 100.140 1.00 111.34 ? 37  ILE B CG1 1 
ATOM   2096 C CG2 . ILE B 2 37  ? 164.610 119.422 102.373 1.00 110.79 ? 37  ILE B CG2 1 
ATOM   2097 C CD1 . ILE B 2 37  ? 166.366 117.800 99.319  1.00 110.60 ? 37  ILE B CD1 1 
ATOM   2098 N N   . ASP B 2 38  ? 167.368 120.433 103.513 1.00 109.78 ? 38  ASP B N   1 
ATOM   2099 C CA  . ASP B 2 38  ? 167.501 121.150 104.772 1.00 110.14 ? 38  ASP B CA  1 
ATOM   2100 C C   . ASP B 2 38  ? 166.194 121.067 105.555 1.00 109.91 ? 38  ASP B C   1 
ATOM   2101 O O   . ASP B 2 38  ? 165.129 121.385 105.008 1.00 110.85 ? 38  ASP B O   1 
ATOM   2102 C CB  . ASP B 2 38  ? 167.874 122.609 104.502 1.00 111.61 ? 38  ASP B CB  1 
ATOM   2103 C CG  . ASP B 2 38  ? 168.392 123.329 105.737 1.00 115.73 ? 38  ASP B CG  1 
ATOM   2104 O OD1 . ASP B 2 38  ? 167.853 123.113 106.842 1.00 117.15 ? 38  ASP B OD1 1 
ATOM   2105 O OD2 . ASP B 2 38  ? 169.348 124.120 105.599 1.00 115.09 ? 38  ASP B OD2 1 
ATOM   2106 N N   . PRO B 2 39  ? 166.226 120.641 106.817 1.00 94.07  ? 39  PRO B N   1 
ATOM   2107 C CA  . PRO B 2 39  ? 164.984 120.532 107.590 1.00 91.17  ? 39  PRO B CA  1 
ATOM   2108 C C   . PRO B 2 39  ? 164.320 121.886 107.784 1.00 93.11  ? 39  PRO B C   1 
ATOM   2109 O O   . PRO B 2 39  ? 164.970 122.933 107.775 1.00 97.31  ? 39  PRO B O   1 
ATOM   2110 C CB  . PRO B 2 39  ? 165.442 119.939 108.929 1.00 91.09  ? 39  PRO B CB  1 
ATOM   2111 C CG  . PRO B 2 39  ? 166.923 120.102 108.960 1.00 94.17  ? 39  PRO B CG  1 
ATOM   2112 C CD  . PRO B 2 39  ? 167.386 120.103 107.544 1.00 95.17  ? 39  PRO B CD  1 
ATOM   2113 N N   . VAL B 2 40  ? 162.997 121.847 107.953 1.00 87.16  ? 40  VAL B N   1 
ATOM   2114 C CA  . VAL B 2 40  ? 162.221 123.074 108.107 1.00 87.27  ? 40  VAL B CA  1 
ATOM   2115 C C   . VAL B 2 40  ? 162.641 123.822 109.365 1.00 91.83  ? 40  VAL B C   1 
ATOM   2116 O O   . VAL B 2 40  ? 162.674 125.058 109.390 1.00 94.37  ? 40  VAL B O   1 
ATOM   2117 C CB  . VAL B 2 40  ? 160.716 122.748 108.110 1.00 91.76  ? 40  VAL B CB  1 
ATOM   2118 C CG1 . VAL B 2 40  ? 160.397 121.712 109.174 1.00 92.00  ? 40  VAL B CG1 1 
ATOM   2119 C CG2 . VAL B 2 40  ? 159.895 124.000 108.330 1.00 88.08  ? 40  VAL B CG2 1 
ATOM   2120 N N   . GLY B 2 41  ? 162.982 123.091 110.421 1.00 104.99 ? 41  GLY B N   1 
ATOM   2121 C CA  . GLY B 2 41  ? 163.292 123.691 111.699 1.00 101.89 ? 41  GLY B CA  1 
ATOM   2122 C C   . GLY B 2 41  ? 162.060 123.854 112.567 1.00 102.06 ? 41  GLY B C   1 
ATOM   2123 O O   . GLY B 2 41  ? 160.916 123.724 112.126 1.00 106.14 ? 41  GLY B O   1 
ATOM   2124 N N   . ARG B 2 42  ? 162.306 124.146 113.840 1.00 100.83 ? 42  ARG B N   1 
ATOM   2125 C CA  . ARG B 2 42  ? 161.221 124.299 114.801 1.00 100.28 ? 42  ARG B CA  1 
ATOM   2126 C C   . ARG B 2 42  ? 160.446 125.570 114.488 1.00 100.88 ? 42  ARG B C   1 
ATOM   2127 O O   . ARG B 2 42  ? 160.920 126.678 114.755 1.00 104.85 ? 42  ARG B O   1 
ATOM   2128 C CB  . ARG B 2 42  ? 161.774 124.331 116.222 1.00 101.56 ? 42  ARG B CB  1 
ATOM   2129 C CG  . ARG B 2 42  ? 162.239 122.979 116.745 1.00 104.06 ? 42  ARG B CG  1 
ATOM   2130 C CD  . ARG B 2 42  ? 161.484 121.830 116.092 1.00 107.85 ? 42  ARG B CD  1 
ATOM   2131 N NE  . ARG B 2 42  ? 161.356 120.684 116.984 1.00 112.24 ? 42  ARG B NE  1 
ATOM   2132 C CZ  . ARG B 2 42  ? 160.307 119.873 117.017 1.00 109.51 ? 42  ARG B CZ  1 
ATOM   2133 N NH1 . ARG B 2 42  ? 159.268 120.055 116.219 1.00 107.35 ? 42  ARG B NH1 1 
ATOM   2134 N NH2 . ARG B 2 42  ? 160.300 118.856 117.874 1.00 105.67 ? 42  ARG B NH2 1 
ATOM   2135 N N   . ILE B 2 43  ? 159.255 125.417 113.921 1.00 95.91  ? 43  ILE B N   1 
ATOM   2136 C CA  . ILE B 2 43  ? 158.393 126.551 113.616 1.00 94.93  ? 43  ILE B CA  1 
ATOM   2137 C C   . ILE B 2 43  ? 157.542 126.836 114.845 1.00 97.18  ? 43  ILE B C   1 
ATOM   2138 O O   . ILE B 2 43  ? 156.834 125.954 115.343 1.00 101.78 ? 43  ILE B O   1 
ATOM   2139 C CB  . ILE B 2 43  ? 157.523 126.281 112.377 1.00 94.01  ? 43  ILE B CB  1 
ATOM   2140 C CG1 . ILE B 2 43  ? 158.395 126.163 111.126 1.00 96.65  ? 43  ILE B CG1 1 
ATOM   2141 C CG2 . ILE B 2 43  ? 156.513 127.394 112.160 1.00 92.37  ? 43  ILE B CG2 1 
ATOM   2142 C CD1 . ILE B 2 43  ? 157.677 125.643 109.903 1.00 96.06  ? 43  ILE B CD1 1 
ATOM   2143 N N   . GLN B 2 44  ? 157.643 128.057 115.358 1.00 100.44 ? 44  GLN B N   1 
ATOM   2144 C CA  . GLN B 2 44  ? 156.862 128.504 116.501 1.00 101.12 ? 44  GLN B CA  1 
ATOM   2145 C C   . GLN B 2 44  ? 155.932 129.610 116.036 1.00 97.10  ? 44  GLN B C   1 
ATOM   2146 O O   . GLN B 2 44  ? 156.325 130.454 115.224 1.00 98.52  ? 44  GLN B O   1 
ATOM   2147 C CB  . GLN B 2 44  ? 157.761 128.991 117.639 1.00 101.45 ? 44  GLN B CB  1 
ATOM   2148 C CG  . GLN B 2 44  ? 158.216 127.883 118.574 1.00 105.30 ? 44  GLN B CG  1 
ATOM   2149 C CD  . GLN B 2 44  ? 157.539 127.950 119.929 1.00 109.15 ? 44  GLN B CD  1 
ATOM   2150 O OE1 . GLN B 2 44  ? 156.568 128.683 120.114 1.00 109.03 ? 44  GLN B OE1 1 
ATOM   2151 N NE2 . GLN B 2 44  ? 158.048 127.180 120.884 1.00 107.24 ? 44  GLN B NE2 1 
ATOM   2152 N N   . MET B 2 45  ? 154.703 129.600 116.537 1.00 89.90  ? 45  MET B N   1 
ATOM   2153 C CA  . MET B 2 45  ? 153.660 130.462 116.014 1.00 88.88  ? 45  MET B CA  1 
ATOM   2154 C C   . MET B 2 45  ? 152.967 131.164 117.167 1.00 95.76  ? 45  MET B C   1 
ATOM   2155 O O   . MET B 2 45  ? 152.888 130.632 118.277 1.00 101.05 ? 45  MET B O   1 
ATOM   2156 C CB  . MET B 2 45  ? 152.651 129.653 115.225 1.00 91.79  ? 45  MET B CB  1 
ATOM   2157 C CG  . MET B 2 45  ? 153.236 129.122 113.950 1.00 96.41  ? 45  MET B CG  1 
ATOM   2158 S SD  . MET B 2 45  ? 152.096 128.829 112.607 1.00 109.91 ? 45  MET B SD  1 
ATOM   2159 C CE  . MET B 2 45  ? 153.291 128.865 111.289 1.00 97.82  ? 45  MET B CE  1 
ATOM   2160 N N   . ARG B 2 46  ? 152.456 132.359 116.900 1.00 84.46  ? 46  ARG B N   1 
ATOM   2161 C CA  . ARG B 2 46  ? 151.781 133.145 117.917 1.00 80.84  ? 46  ARG B CA  1 
ATOM   2162 C C   . ARG B 2 46  ? 150.377 133.494 117.454 1.00 77.68  ? 46  ARG B C   1 
ATOM   2163 O O   . ARG B 2 46  ? 150.144 133.735 116.261 1.00 86.68  ? 46  ARG B O   1 
ATOM   2164 C CB  . ARG B 2 46  ? 152.560 134.421 118.241 1.00 88.80  ? 46  ARG B CB  1 
ATOM   2165 C CG  . ARG B 2 46  ? 154.066 134.263 118.154 1.00 92.54  ? 46  ARG B CG  1 
ATOM   2166 C CD  . ARG B 2 46  ? 154.768 135.068 119.240 1.00 88.59  ? 46  ARG B CD  1 
ATOM   2167 N NE  . ARG B 2 46  ? 154.633 134.474 120.566 1.00 89.72  ? 46  ARG B NE  1 
ATOM   2168 C CZ  . ARG B 2 46  ? 155.069 133.269 120.911 1.00 93.90  ? 46  ARG B CZ  1 
ATOM   2169 N NH1 . ARG B 2 46  ? 155.736 132.501 120.064 1.00 93.88  ? 46  ARG B NH1 1 
ATOM   2170 N NH2 . ARG B 2 46  ? 154.847 132.829 122.146 1.00 92.67  ? 46  ARG B NH2 1 
ATOM   2171 N N   . THR B 2 47  ? 149.451 133.510 118.410 1.00 67.09  ? 47  THR B N   1 
ATOM   2172 C CA  . THR B 2 47  ? 148.081 133.928 118.162 1.00 72.56  ? 47  THR B CA  1 
ATOM   2173 C C   . THR B 2 47  ? 148.032 135.441 118.026 1.00 76.10  ? 47  THR B C   1 
ATOM   2174 O O   . THR B 2 47  ? 147.811 136.153 119.010 1.00 83.03  ? 47  THR B O   1 
ATOM   2175 C CB  . THR B 2 47  ? 147.160 133.464 119.290 1.00 77.61  ? 47  THR B CB  1 
ATOM   2176 O OG1 . THR B 2 47  ? 147.332 132.058 119.503 1.00 83.12  ? 47  THR B OG1 1 
ATOM   2177 C CG2 . THR B 2 47  ? 145.713 133.741 118.938 1.00 74.23  ? 47  THR B CG2 1 
ATOM   2178 N N   . ARG B 2 48  ? 148.251 135.939 116.810 1.00 81.97  ? 48  ARG B N   1 
ATOM   2179 C CA  . ARG B 2 48  ? 148.293 137.380 116.604 1.00 81.25  ? 48  ARG B CA  1 
ATOM   2180 C C   . ARG B 2 48  ? 146.933 138.024 116.828 1.00 85.32  ? 48  ARG B C   1 
ATOM   2181 O O   . ARG B 2 48  ? 146.863 139.207 117.176 1.00 90.13  ? 48  ARG B O   1 
ATOM   2182 C CB  . ARG B 2 48  ? 148.810 137.690 115.202 1.00 80.30  ? 48  ARG B CB  1 
ATOM   2183 C CG  . ARG B 2 48  ? 150.283 137.368 114.986 1.00 83.44  ? 48  ARG B CG  1 
ATOM   2184 C CD  . ARG B 2 48  ? 151.062 137.345 116.292 1.00 87.96  ? 48  ARG B CD  1 
ATOM   2185 N NE  . ARG B 2 48  ? 152.399 137.903 116.139 1.00 90.01  ? 48  ARG B NE  1 
ATOM   2186 C CZ  . ARG B 2 48  ? 153.430 137.249 115.623 1.00 92.78  ? 48  ARG B CZ  1 
ATOM   2187 N NH1 . ARG B 2 48  ? 153.317 135.998 115.209 1.00 91.39  ? 48  ARG B NH1 1 
ATOM   2188 N NH2 . ARG B 2 48  ? 154.604 137.864 115.522 1.00 91.83  ? 48  ARG B NH2 1 
ATOM   2189 N N   . ARG B 2 49  ? 145.850 137.277 116.640 1.00 73.18  ? 49  ARG B N   1 
ATOM   2190 C CA  . ARG B 2 49  ? 144.521 137.814 116.885 1.00 71.14  ? 49  ARG B CA  1 
ATOM   2191 C C   . ARG B 2 49  ? 143.556 136.677 117.174 1.00 74.12  ? 49  ARG B C   1 
ATOM   2192 O O   . ARG B 2 49  ? 143.615 135.625 116.534 1.00 85.73  ? 49  ARG B O   1 
ATOM   2193 C CB  . ARG B 2 49  ? 144.026 138.637 115.694 1.00 70.99  ? 49  ARG B CB  1 
ATOM   2194 C CG  . ARG B 2 49  ? 143.784 140.090 116.031 1.00 76.62  ? 49  ARG B CG  1 
ATOM   2195 C CD  . ARG B 2 49  ? 143.741 140.937 114.783 1.00 78.61  ? 49  ARG B CD  1 
ATOM   2196 N NE  . ARG B 2 49  ? 145.072 141.285 114.306 1.00 73.91  ? 49  ARG B NE  1 
ATOM   2197 C CZ  . ARG B 2 49  ? 145.829 142.239 114.828 1.00 76.05  ? 49  ARG B CZ  1 
ATOM   2198 N NH1 . ARG B 2 49  ? 145.421 142.958 115.860 1.00 78.62  ? 49  ARG B NH1 1 
ATOM   2199 N NH2 . ARG B 2 49  ? 147.024 142.480 114.300 1.00 74.75  ? 49  ARG B NH2 1 
ATOM   2200 N N   . THR B 2 50  ? 142.672 136.898 118.141 1.00 70.18  ? 50  THR B N   1 
ATOM   2201 C CA  . THR B 2 50  ? 141.615 135.956 118.480 1.00 67.94  ? 50  THR B CA  1 
ATOM   2202 C C   . THR B 2 50  ? 140.277 136.591 118.136 1.00 73.83  ? 50  THR B C   1 
ATOM   2203 O O   . THR B 2 50  ? 139.954 137.673 118.635 1.00 79.60  ? 50  THR B O   1 
ATOM   2204 C CB  . THR B 2 50  ? 141.662 135.578 119.959 1.00 71.36  ? 50  THR B CB  1 
ATOM   2205 O OG1 . THR B 2 50  ? 142.864 134.847 120.228 1.00 81.03  ? 50  THR B OG1 1 
ATOM   2206 C CG2 . THR B 2 50  ? 140.462 134.724 120.323 1.00 71.43  ? 50  THR B CG2 1 
ATOM   2207 N N   . LEU B 2 51  ? 139.505 135.920 117.291 1.00 71.72  ? 51  LEU B N   1 
ATOM   2208 C CA  . LEU B 2 51  ? 138.217 136.425 116.828 1.00 69.74  ? 51  LEU B CA  1 
ATOM   2209 C C   . LEU B 2 51  ? 137.125 135.760 117.654 1.00 71.56  ? 51  LEU B C   1 
ATOM   2210 O O   . LEU B 2 51  ? 136.745 134.616 117.396 1.00 78.53  ? 51  LEU B O   1 
ATOM   2211 C CB  . LEU B 2 51  ? 138.037 136.154 115.339 1.00 72.62  ? 51  LEU B CB  1 
ATOM   2212 C CG  . LEU B 2 51  ? 139.260 136.348 114.444 1.00 76.47  ? 51  LEU B CG  1 
ATOM   2213 C CD1 . LEU B 2 51  ? 138.967 135.861 113.040 1.00 76.79  ? 51  LEU B CD1 1 
ATOM   2214 C CD2 . LEU B 2 51  ? 139.670 137.804 114.427 1.00 79.37  ? 51  LEU B CD2 1 
ATOM   2215 N N   . ARG B 2 52  ? 136.617 136.480 118.648 1.00 72.07  ? 52  ARG B N   1 
ATOM   2216 C CA  . ARG B 2 52  ? 135.568 135.979 119.519 1.00 74.13  ? 52  ARG B CA  1 
ATOM   2217 C C   . ARG B 2 52  ? 134.248 136.661 119.192 1.00 72.88  ? 52  ARG B C   1 
ATOM   2218 O O   . ARG B 2 52  ? 134.217 137.777 118.667 1.00 78.29  ? 52  ARG B O   1 
ATOM   2219 C CB  . ARG B 2 52  ? 135.916 136.198 120.993 1.00 73.66  ? 52  ARG B CB  1 
ATOM   2220 C CG  . ARG B 2 52  ? 136.580 137.525 121.289 1.00 74.37  ? 52  ARG B CG  1 
ATOM   2221 C CD  . ARG B 2 52  ? 137.139 137.547 122.698 1.00 71.45  ? 52  ARG B CD  1 
ATOM   2222 N NE  . ARG B 2 52  ? 138.573 137.293 122.723 1.00 72.00  ? 52  ARG B NE  1 
ATOM   2223 C CZ  . ARG B 2 52  ? 139.148 136.322 123.419 1.00 76.07  ? 52  ARG B CZ  1 
ATOM   2224 N NH1 . ARG B 2 52  ? 138.435 135.480 124.147 1.00 79.05  ? 52  ARG B NH1 1 
ATOM   2225 N NH2 . ARG B 2 52  ? 140.471 136.194 123.384 1.00 78.33  ? 52  ARG B NH2 1 
ATOM   2226 N N   . GLY B 2 53  ? 133.155 135.979 119.513 1.00 72.79  ? 53  GLY B N   1 
ATOM   2227 C CA  . GLY B 2 53  ? 131.835 136.470 119.184 1.00 75.50  ? 53  GLY B CA  1 
ATOM   2228 C C   . GLY B 2 53  ? 130.880 135.357 118.815 1.00 75.53  ? 53  GLY B C   1 
ATOM   2229 O O   . GLY B 2 53  ? 129.660 135.532 118.872 1.00 82.93  ? 53  GLY B O   1 
ATOM   2230 N N   . HIS B 2 54  ? 131.420 134.205 118.433 1.00 67.58  ? 54  HIS B N   1 
ATOM   2231 C CA  . HIS B 2 54  ? 130.585 133.035 118.223 1.00 71.74  ? 54  HIS B CA  1 
ATOM   2232 C C   . HIS B 2 54  ? 130.145 132.460 119.564 1.00 77.31  ? 54  HIS B C   1 
ATOM   2233 O O   . HIS B 2 54  ? 130.872 132.517 120.558 1.00 83.53  ? 54  HIS B O   1 
ATOM   2234 C CB  . HIS B 2 54  ? 131.331 131.973 117.418 1.00 77.85  ? 54  HIS B CB  1 
ATOM   2235 C CG  . HIS B 2 54  ? 131.235 132.157 115.936 1.00 80.45  ? 54  HIS B CG  1 
ATOM   2236 N ND1 . HIS B 2 54  ? 130.065 131.962 115.236 1.00 77.16  ? 54  HIS B ND1 1 
ATOM   2237 C CD2 . HIS B 2 54  ? 132.167 132.504 115.018 1.00 80.33  ? 54  HIS B CD2 1 
ATOM   2238 C CE1 . HIS B 2 54  ? 130.278 132.185 113.953 1.00 74.63  ? 54  HIS B CE1 1 
ATOM   2239 N NE2 . HIS B 2 54  ? 131.546 132.517 113.793 1.00 76.82  ? 54  HIS B NE2 1 
ATOM   2240 N N   . LEU B 2 55  ? 128.937 131.905 119.588 1.00 80.29  ? 55  LEU B N   1 
ATOM   2241 C CA  . LEU B 2 55  ? 128.362 131.352 120.806 1.00 78.03  ? 55  LEU B CA  1 
ATOM   2242 C C   . LEU B 2 55  ? 128.020 129.875 120.648 1.00 82.77  ? 55  LEU B C   1 
ATOM   2243 O O   . LEU B 2 55  ? 127.113 129.364 121.306 1.00 89.76  ? 55  LEU B O   1 
ATOM   2244 C CB  . LEU B 2 55  ? 127.133 132.154 121.226 1.00 76.08  ? 55  LEU B CB  1 
ATOM   2245 C CG  . LEU B 2 55  ? 127.479 133.571 121.680 1.00 80.61  ? 55  LEU B CG  1 
ATOM   2246 C CD1 . LEU B 2 55  ? 126.251 134.456 121.686 1.00 80.16  ? 55  LEU B CD1 1 
ATOM   2247 C CD2 . LEU B 2 55  ? 128.131 133.544 123.052 1.00 80.98  ? 55  LEU B CD2 1 
ATOM   2248 N N   . ALA B 2 56  ? 128.748 129.181 119.780 1.00 79.82  ? 56  ALA B N   1 
ATOM   2249 C CA  . ALA B 2 56  ? 128.579 127.750 119.575 1.00 78.06  ? 56  ALA B CA  1 
ATOM   2250 C C   . ALA B 2 56  ? 129.821 127.235 118.864 1.00 78.36  ? 56  ALA B C   1 
ATOM   2251 O O   . ALA B 2 56  ? 130.748 127.993 118.570 1.00 84.22  ? 56  ALA B O   1 
ATOM   2252 C CB  . ALA B 2 56  ? 127.306 127.443 118.783 1.00 81.27  ? 56  ALA B CB  1 
ATOM   2253 N N   . LYS B 2 57  ? 129.834 125.938 118.582 1.00 76.70  ? 57  LYS B N   1 
ATOM   2254 C CA  . LYS B 2 57  ? 130.996 125.332 117.949 1.00 77.13  ? 57  LYS B CA  1 
ATOM   2255 C C   . LYS B 2 57  ? 131.132 125.824 116.514 1.00 80.17  ? 57  LYS B C   1 
ATOM   2256 O O   . LYS B 2 57  ? 130.189 125.737 115.723 1.00 86.94  ? 57  LYS B O   1 
ATOM   2257 C CB  . LYS B 2 57  ? 130.881 123.809 117.985 1.00 79.84  ? 57  LYS B CB  1 
ATOM   2258 C CG  . LYS B 2 57  ? 130.641 123.251 119.376 1.00 83.02  ? 57  LYS B CG  1 
ATOM   2259 C CD  . LYS B 2 57  ? 129.726 122.038 119.350 1.00 81.45  ? 57  LYS B CD  1 
ATOM   2260 C CE  . LYS B 2 57  ? 130.513 120.748 119.236 1.00 76.50  ? 57  LYS B CE  1 
ATOM   2261 N NZ  . LYS B 2 57  ? 130.735 120.366 117.818 1.00 78.68  ? 57  LYS B NZ  1 
ATOM   2262 N N   . ILE B 2 58  ? 132.309 126.342 116.183 1.00 74.42  ? 58  ILE B N   1 
ATOM   2263 C CA  . ILE B 2 58  ? 132.604 126.767 114.820 1.00 70.17  ? 58  ILE B CA  1 
ATOM   2264 C C   . ILE B 2 58  ? 132.938 125.536 113.993 1.00 76.78  ? 58  ILE B C   1 
ATOM   2265 O O   . ILE B 2 58  ? 133.818 124.750 114.359 1.00 85.27  ? 58  ILE B O   1 
ATOM   2266 C CB  . ILE B 2 58  ? 133.760 127.777 114.802 1.00 72.42  ? 58  ILE B CB  1 
ATOM   2267 C CG1 . ILE B 2 58  ? 133.328 129.088 115.453 1.00 74.32  ? 58  ILE B CG1 1 
ATOM   2268 C CG2 . ILE B 2 58  ? 134.232 128.018 113.385 1.00 73.13  ? 58  ILE B CG2 1 
ATOM   2269 C CD1 . ILE B 2 58  ? 134.482 129.969 115.852 1.00 76.05  ? 58  ILE B CD1 1 
ATOM   2270 N N   . TYR B 2 59  ? 132.236 125.362 112.874 1.00 76.05  ? 59  TYR B N   1 
ATOM   2271 C CA  . TYR B 2 59  ? 132.405 124.174 112.052 1.00 78.61  ? 59  TYR B CA  1 
ATOM   2272 C C   . TYR B 2 59  ? 133.164 124.412 110.759 1.00 80.98  ? 59  TYR B C   1 
ATOM   2273 O O   . TYR B 2 59  ? 133.765 123.469 110.238 1.00 87.66  ? 59  TYR B O   1 
ATOM   2274 C CB  . TYR B 2 59  ? 131.039 123.560 111.718 1.00 81.52  ? 59  TYR B CB  1 
ATOM   2275 C CG  . TYR B 2 59  ? 130.686 122.392 112.600 1.00 82.24  ? 59  TYR B CG  1 
ATOM   2276 C CD1 . TYR B 2 59  ? 131.388 121.201 112.514 1.00 83.91  ? 59  TYR B CD1 1 
ATOM   2277 C CD2 . TYR B 2 59  ? 129.670 122.485 113.532 1.00 80.11  ? 59  TYR B CD2 1 
ATOM   2278 C CE1 . TYR B 2 59  ? 131.075 120.131 113.322 1.00 88.01  ? 59  TYR B CE1 1 
ATOM   2279 C CE2 . TYR B 2 59  ? 129.351 121.421 114.346 1.00 79.90  ? 59  TYR B CE2 1 
ATOM   2280 C CZ  . TYR B 2 59  ? 130.055 120.247 114.237 1.00 89.17  ? 59  TYR B CZ  1 
ATOM   2281 O OH  . TYR B 2 59  ? 129.739 119.182 115.048 1.00 94.04  ? 59  TYR B OH  1 
ATOM   2282 N N   . ALA B 2 60  ? 133.160 125.631 110.232 1.00 73.00  ? 60  ALA B N   1 
ATOM   2283 C CA  . ALA B 2 60  ? 133.852 125.897 108.984 1.00 70.56  ? 60  ALA B CA  1 
ATOM   2284 C C   . ALA B 2 60  ? 134.352 127.330 108.976 1.00 75.96  ? 60  ALA B C   1 
ATOM   2285 O O   . ALA B 2 60  ? 133.880 128.182 109.732 1.00 87.49  ? 60  ALA B O   1 
ATOM   2286 C CB  . ALA B 2 60  ? 132.951 125.646 107.775 1.00 75.43  ? 60  ALA B CB  1 
ATOM   2287 N N   . MET B 2 61  ? 135.321 127.580 108.102 1.00 73.08  ? 61  MET B N   1 
ATOM   2288 C CA  . MET B 2 61  ? 135.914 128.900 107.961 1.00 67.38  ? 61  MET B CA  1 
ATOM   2289 C C   . MET B 2 61  ? 136.624 128.959 106.621 1.00 73.72  ? 61  MET B C   1 
ATOM   2290 O O   . MET B 2 61  ? 137.427 128.075 106.311 1.00 84.38  ? 61  MET B O   1 
ATOM   2291 C CB  . MET B 2 61  ? 136.895 129.187 109.098 1.00 67.70  ? 61  MET B CB  1 
ATOM   2292 C CG  . MET B 2 61  ? 137.767 130.395 108.853 1.00 73.92  ? 61  MET B CG  1 
ATOM   2293 S SD  . MET B 2 61  ? 139.359 129.933 108.157 1.00 91.52  ? 61  MET B SD  1 
ATOM   2294 C CE  . MET B 2 61  ? 139.695 128.446 109.088 1.00 79.34  ? 61  MET B CE  1 
ATOM   2295 N N   . HIS B 2 62  ? 136.337 129.990 105.834 1.00 67.70  ? 62  HIS B N   1 
ATOM   2296 C CA  . HIS B 2 62  ? 137.024 130.190 104.569 1.00 67.12  ? 62  HIS B CA  1 
ATOM   2297 C C   . HIS B 2 62  ? 137.595 131.595 104.501 1.00 72.24  ? 62  HIS B C   1 
ATOM   2298 O O   . HIS B 2 62  ? 136.973 132.556 104.960 1.00 80.47  ? 62  HIS B O   1 
ATOM   2299 C CB  . HIS B 2 62  ? 136.110 129.951 103.370 1.00 71.44  ? 62  HIS B CB  1 
ATOM   2300 C CG  . HIS B 2 62  ? 136.853 129.629 102.113 1.00 76.60  ? 62  HIS B CG  1 
ATOM   2301 N ND1 . HIS B 2 62  ? 136.425 130.031 100.868 1.00 81.73  ? 62  HIS B ND1 1 
ATOM   2302 C CD2 . HIS B 2 62  ? 138.011 128.957 101.912 1.00 72.86  ? 62  HIS B CD2 1 
ATOM   2303 C CE1 . HIS B 2 62  ? 137.281 129.613 99.953  1.00 73.48  ? 62  HIS B CE1 1 
ATOM   2304 N NE2 . HIS B 2 62  ? 138.252 128.959 100.561 1.00 74.44  ? 62  HIS B NE2 1 
ATOM   2305 N N   . TRP B 2 63  ? 138.785 131.695 103.925 1.00 74.43  ? 63  TRP B N   1 
ATOM   2306 C CA  . TRP B 2 63  ? 139.478 132.961 103.778 1.00 67.69  ? 63  TRP B CA  1 
ATOM   2307 C C   . TRP B 2 63  ? 139.011 133.674 102.517 1.00 69.94  ? 63  TRP B C   1 
ATOM   2308 O O   . TRP B 2 63  ? 138.749 133.050 101.486 1.00 79.44  ? 63  TRP B O   1 
ATOM   2309 C CB  . TRP B 2 63  ? 140.984 132.721 103.703 1.00 69.28  ? 63  TRP B CB  1 
ATOM   2310 C CG  . TRP B 2 63  ? 141.715 132.997 104.968 1.00 66.94  ? 63  TRP B CG  1 
ATOM   2311 C CD1 . TRP B 2 63  ? 142.463 132.114 105.682 1.00 67.43  ? 63  TRP B CD1 1 
ATOM   2312 C CD2 . TRP B 2 63  ? 141.798 134.245 105.661 1.00 73.13  ? 63  TRP B CD2 1 
ATOM   2313 N NE1 . TRP B 2 63  ? 142.994 132.726 106.786 1.00 69.77  ? 63  TRP B NE1 1 
ATOM   2314 C CE2 . TRP B 2 63  ? 142.600 134.036 106.797 1.00 69.11  ? 63  TRP B CE2 1 
ATOM   2315 C CE3 . TRP B 2 63  ? 141.266 135.516 105.435 1.00 80.38  ? 63  TRP B CE3 1 
ATOM   2316 C CZ2 . TRP B 2 63  ? 142.887 135.049 107.701 1.00 69.45  ? 63  TRP B CZ2 1 
ATOM   2317 C CZ3 . TRP B 2 63  ? 141.550 136.519 106.336 1.00 78.74  ? 63  TRP B CZ3 1 
ATOM   2318 C CH2 . TRP B 2 63  ? 142.354 136.280 107.453 1.00 72.16  ? 63  TRP B CH2 1 
ATOM   2319 N N   . GLY B 2 64  ? 138.908 134.995 102.604 1.00 76.41  ? 64  GLY B N   1 
ATOM   2320 C CA  . GLY B 2 64  ? 138.648 135.782 101.421 1.00 79.67  ? 64  GLY B CA  1 
ATOM   2321 C C   . GLY B 2 64  ? 139.853 135.826 100.504 1.00 82.43  ? 64  GLY B C   1 
ATOM   2322 O O   . GLY B 2 64  ? 140.983 135.537 100.897 1.00 86.17  ? 64  GLY B O   1 
ATOM   2323 N N   . THR B 2 65  ? 139.606 136.190 99.246  1.00 75.91  ? 65  THR B N   1 
ATOM   2324 C CA  . THR B 2 65  ? 140.702 136.243 98.285  1.00 78.39  ? 65  THR B CA  1 
ATOM   2325 C C   . THR B 2 65  ? 141.641 137.406 98.572  1.00 82.45  ? 65  THR B C   1 
ATOM   2326 O O   . THR B 2 65  ? 142.819 137.357 98.201  1.00 83.30  ? 65  THR B O   1 
ATOM   2327 C CB  . THR B 2 65  ? 140.155 136.340 96.865  1.00 81.27  ? 65  THR B CB  1 
ATOM   2328 O OG1 . THR B 2 65  ? 139.008 135.494 96.744  1.00 88.66  ? 65  THR B OG1 1 
ATOM   2329 C CG2 . THR B 2 65  ? 141.205 135.893 95.863  1.00 83.05  ? 65  THR B CG2 1 
ATOM   2330 N N   . ASP B 2 66  ? 141.146 138.451 99.234  1.00 81.83  ? 66  ASP B N   1 
ATOM   2331 C CA  . ASP B 2 66  ? 141.993 139.574 99.610  1.00 81.29  ? 66  ASP B CA  1 
ATOM   2332 C C   . ASP B 2 66  ? 142.906 139.249 100.781 1.00 77.29  ? 66  ASP B C   1 
ATOM   2333 O O   . ASP B 2 66  ? 143.731 140.091 101.150 1.00 83.02  ? 66  ASP B O   1 
ATOM   2334 C CB  . ASP B 2 66  ? 141.133 140.789 99.952  1.00 82.55  ? 66  ASP B CB  1 
ATOM   2335 C CG  . ASP B 2 66  ? 139.991 140.447 100.879 1.00 86.33  ? 66  ASP B CG  1 
ATOM   2336 O OD1 . ASP B 2 66  ? 139.820 139.251 101.192 1.00 88.86  ? 66  ASP B OD1 1 
ATOM   2337 O OD2 . ASP B 2 66  ? 139.263 141.371 101.295 1.00 88.00  ? 66  ASP B OD2 1 
ATOM   2338 N N   . SER B 2 67  ? 142.761 138.067 101.378 1.00 68.70  ? 67  SER B N   1 
ATOM   2339 C CA  . SER B 2 67  ? 143.574 137.596 102.493 1.00 71.82  ? 67  SER B CA  1 
ATOM   2340 C C   . SER B 2 67  ? 143.361 138.411 103.758 1.00 74.95  ? 67  SER B C   1 
ATOM   2341 O O   . SER B 2 67  ? 144.180 138.352 104.678 1.00 75.46  ? 67  SER B O   1 
ATOM   2342 C CB  . SER B 2 67  ? 145.060 137.578 102.132 1.00 72.65  ? 67  SER B CB  1 
ATOM   2343 O OG  . SER B 2 67  ? 145.268 136.963 100.874 1.00 83.02  ? 67  SER B OG  1 
ATOM   2344 N N   . ARG B 2 68  ? 142.286 139.171 103.824 1.00 73.86  ? 68  ARG B N   1 
ATOM   2345 C CA  . ARG B 2 68  ? 141.965 139.951 105.011 1.00 71.17  ? 68  ARG B CA  1 
ATOM   2346 C C   . ARG B 2 68  ? 140.559 139.688 105.523 1.00 66.74  ? 68  ARG B C   1 
ATOM   2347 O O   . ARG B 2 68  ? 140.352 139.645 106.736 1.00 71.29  ? 68  ARG B O   1 
ATOM   2348 C CB  . ARG B 2 68  ? 142.144 141.444 104.715 1.00 67.82  ? 68  ARG B CB  1 
ATOM   2349 C CG  . ARG B 2 68  ? 141.889 142.346 105.901 1.00 71.38  ? 68  ARG B CG  1 
ATOM   2350 C CD  . ARG B 2 68  ? 141.790 143.795 105.474 1.00 72.31  ? 68  ARG B CD  1 
ATOM   2351 N NE  . ARG B 2 68  ? 141.355 144.654 106.568 1.00 74.39  ? 68  ARG B NE  1 
ATOM   2352 C CZ  . ARG B 2 68  ? 141.863 145.850 106.826 1.00 69.33  ? 68  ARG B CZ  1 
ATOM   2353 N NH1 . ARG B 2 68  ? 142.823 146.368 106.080 1.00 69.92  ? 68  ARG B NH1 1 
ATOM   2354 N NH2 . ARG B 2 68  ? 141.393 146.544 107.857 1.00 70.08  ? 68  ARG B NH2 1 
ATOM   2355 N N   . LEU B 2 69  ? 139.591 139.504 104.633 1.00 59.57  ? 69  LEU B N   1 
ATOM   2356 C CA  . LEU B 2 69  ? 138.235 139.193 105.049 1.00 61.16  ? 69  LEU B CA  1 
ATOM   2357 C C   . LEU B 2 69  ? 138.097 137.699 105.299 1.00 67.98  ? 69  LEU B C   1 
ATOM   2358 O O   . LEU B 2 69  ? 138.633 136.878 104.551 1.00 72.18  ? 69  LEU B O   1 
ATOM   2359 C CB  . LEU B 2 69  ? 137.232 139.645 103.990 1.00 67.32  ? 69  LEU B CB  1 
ATOM   2360 C CG  . LEU B 2 69  ? 136.863 141.127 103.999 1.00 66.83  ? 69  LEU B CG  1 
ATOM   2361 C CD1 . LEU B 2 69  ? 136.213 141.519 102.686 1.00 63.72  ? 69  LEU B CD1 1 
ATOM   2362 C CD2 . LEU B 2 69  ? 135.944 141.436 105.160 1.00 64.92  ? 69  LEU B CD2 1 
ATOM   2363 N N   . LEU B 2 70  ? 137.368 137.348 106.353 1.00 78.41  ? 70  LEU B N   1 
ATOM   2364 C CA  . LEU B 2 70  ? 137.218 135.962 106.766 1.00 68.93  ? 70  LEU B CA  1 
ATOM   2365 C C   . LEU B 2 70  ? 135.744 135.662 106.983 1.00 68.57  ? 70  LEU B C   1 
ATOM   2366 O O   . LEU B 2 70  ? 134.970 136.543 107.350 1.00 82.26  ? 70  LEU B O   1 
ATOM   2367 C CB  . LEU B 2 70  ? 138.014 135.689 108.046 1.00 68.08  ? 70  LEU B CB  1 
ATOM   2368 C CG  . LEU B 2 70  ? 138.122 134.270 108.590 1.00 72.88  ? 70  LEU B CG  1 
ATOM   2369 C CD1 . LEU B 2 70  ? 139.489 134.097 109.198 1.00 76.39  ? 70  LEU B CD1 1 
ATOM   2370 C CD2 . LEU B 2 70  ? 137.047 133.995 109.624 1.00 75.77  ? 70  LEU B CD2 1 
ATOM   2371 N N   . VAL B 2 71  ? 135.356 134.412 106.750 1.00 61.22  ? 71  VAL B N   1 
ATOM   2372 C CA  . VAL B 2 71  ? 133.982 133.965 106.942 1.00 64.50  ? 71  VAL B CA  1 
ATOM   2373 C C   . VAL B 2 71  ? 133.999 132.749 107.854 1.00 67.08  ? 71  VAL B C   1 
ATOM   2374 O O   . VAL B 2 71  ? 134.768 131.810 107.626 1.00 79.27  ? 71  VAL B O   1 
ATOM   2375 C CB  . VAL B 2 71  ? 133.298 133.642 105.601 1.00 71.62  ? 71  VAL B CB  1 
ATOM   2376 C CG1 . VAL B 2 71  ? 132.201 132.630 105.794 1.00 71.56  ? 71  VAL B CG1 1 
ATOM   2377 C CG2 . VAL B 2 71  ? 132.723 134.900 105.002 1.00 74.78  ? 71  VAL B CG2 1 
ATOM   2378 N N   . SER B 2 72  ? 133.157 132.769 108.885 1.00 64.02  ? 72  SER B N   1 
ATOM   2379 C CA  . SER B 2 72  ? 133.092 131.689 109.856 1.00 68.01  ? 72  SER B CA  1 
ATOM   2380 C C   . SER B 2 72  ? 131.649 131.275 110.088 1.00 69.31  ? 72  SER B C   1 
ATOM   2381 O O   . SER B 2 72  ? 130.766 132.125 110.240 1.00 78.97  ? 72  SER B O   1 
ATOM   2382 C CB  . SER B 2 72  ? 133.716 132.100 111.179 1.00 78.40  ? 72  SER B CB  1 
ATOM   2383 O OG  . SER B 2 72  ? 133.173 133.325 111.637 1.00 87.03  ? 72  SER B OG  1 
ATOM   2384 N N   . ALA B 2 73  ? 131.424 129.966 110.142 1.00 67.36  ? 73  ALA B N   1 
ATOM   2385 C CA  . ALA B 2 73  ? 130.104 129.390 110.338 1.00 69.26  ? 73  ALA B CA  1 
ATOM   2386 C C   . ALA B 2 73  ? 130.086 128.572 111.619 1.00 73.19  ? 73  ALA B C   1 
ATOM   2387 O O   . ALA B 2 73  ? 131.028 127.824 111.902 1.00 86.63  ? 73  ALA B O   1 
ATOM   2388 C CB  . ALA B 2 73  ? 129.709 128.508 109.155 1.00 72.12  ? 73  ALA B CB  1 
ATOM   2389 N N   . SER B 2 74  ? 129.011 128.709 112.389 1.00 72.38  ? 74  SER B N   1 
ATOM   2390 C CA  . SER B 2 74  ? 128.885 127.992 113.647 1.00 80.50  ? 74  SER B CA  1 
ATOM   2391 C C   . SER B 2 74  ? 127.432 127.595 113.855 1.00 78.08  ? 74  SER B C   1 
ATOM   2392 O O   . SER B 2 74  ? 126.523 128.115 113.205 1.00 85.73  ? 74  SER B O   1 
ATOM   2393 C CB  . SER B 2 74  ? 129.395 128.830 114.820 1.00 85.53  ? 74  SER B CB  1 
ATOM   2394 O OG  . SER B 2 74  ? 129.226 128.141 116.045 1.00 87.61  ? 74  SER B OG  1 
ATOM   2395 N N   . GLN B 2 75  ? 127.224 126.664 114.786 1.00 74.53  ? 75  GLN B N   1 
ATOM   2396 C CA  . GLN B 2 75  ? 125.903 126.096 115.020 1.00 78.92  ? 75  GLN B CA  1 
ATOM   2397 C C   . GLN B 2 75  ? 124.934 127.075 115.661 1.00 87.05  ? 75  GLN B C   1 
ATOM   2398 O O   . GLN B 2 75  ? 123.742 126.763 115.755 1.00 91.57  ? 75  GLN B O   1 
ATOM   2399 C CB  . GLN B 2 75  ? 126.018 124.847 115.889 1.00 80.83  ? 75  GLN B CB  1 
ATOM   2400 C CG  . GLN B 2 75  ? 127.041 123.853 115.387 1.00 88.40  ? 75  GLN B CG  1 
ATOM   2401 C CD  . GLN B 2 75  ? 126.520 123.000 114.248 1.00 92.07  ? 75  GLN B CD  1 
ATOM   2402 O OE1 . GLN B 2 75  ? 126.188 121.832 114.439 1.00 92.99  ? 75  GLN B OE1 1 
ATOM   2403 N NE2 . GLN B 2 75  ? 126.461 123.574 113.052 1.00 91.33  ? 75  GLN B NE2 1 
ATOM   2404 N N   . ASP B 2 76  ? 125.403 128.240 116.106 1.00 86.60  ? 76  ASP B N   1 
ATOM   2405 C CA  . ASP B 2 76  ? 124.488 129.248 116.621 1.00 84.04  ? 76  ASP B CA  1 
ATOM   2406 C C   . ASP B 2 76  ? 123.586 129.814 115.536 1.00 85.55  ? 76  ASP B C   1 
ATOM   2407 O O   . ASP B 2 76  ? 122.618 130.510 115.859 1.00 91.02  ? 76  ASP B O   1 
ATOM   2408 C CB  . ASP B 2 76  ? 125.271 130.377 117.289 1.00 88.56  ? 76  ASP B CB  1 
ATOM   2409 C CG  . ASP B 2 76  ? 126.357 130.934 116.398 1.00 92.32  ? 76  ASP B CG  1 
ATOM   2410 O OD1 . ASP B 2 76  ? 126.673 130.289 115.379 1.00 90.55  ? 76  ASP B OD1 1 
ATOM   2411 O OD2 . ASP B 2 76  ? 126.896 132.014 116.717 1.00 95.91  ? 76  ASP B OD2 1 
ATOM   2412 N N   . GLY B 2 77  ? 123.876 129.532 114.270 1.00 86.47  ? 77  GLY B N   1 
ATOM   2413 C CA  . GLY B 2 77  ? 123.050 129.993 113.178 1.00 88.04  ? 77  GLY B CA  1 
ATOM   2414 C C   . GLY B 2 77  ? 123.496 131.283 112.538 1.00 86.83  ? 77  GLY B C   1 
ATOM   2415 O O   . GLY B 2 77  ? 122.688 131.932 111.865 1.00 91.04  ? 77  GLY B O   1 
ATOM   2416 N N   . LYS B 2 78  ? 124.749 131.686 112.729 1.00 70.64  ? 78  LYS B N   1 
ATOM   2417 C CA  . LYS B 2 78  ? 125.233 132.958 112.214 1.00 70.94  ? 78  LYS B CA  1 
ATOM   2418 C C   . LYS B 2 78  ? 126.501 132.744 111.406 1.00 68.05  ? 78  LYS B C   1 
ATOM   2419 O O   . LYS B 2 78  ? 127.432 132.077 111.865 1.00 74.90  ? 78  LYS B O   1 
ATOM   2420 C CB  . LYS B 2 78  ? 125.490 133.950 113.351 1.00 70.19  ? 78  LYS B CB  1 
ATOM   2421 C CG  . LYS B 2 78  ? 124.395 133.965 114.396 1.00 73.86  ? 78  LYS B CG  1 
ATOM   2422 C CD  . LYS B 2 78  ? 123.656 135.283 114.399 1.00 74.23  ? 78  LYS B CD  1 
ATOM   2423 C CE  . LYS B 2 78  ? 122.445 135.222 115.306 1.00 77.27  ? 78  LYS B CE  1 
ATOM   2424 N NZ  . LYS B 2 78  ? 121.179 135.175 114.528 1.00 78.38  ? 78  LYS B NZ  1 
ATOM   2425 N N   . LEU B 2 79  ? 126.524 133.309 110.205 1.00 75.51  ? 79  LEU B N   1 
ATOM   2426 C CA  . LEU B 2 79  ? 127.713 133.373 109.365 1.00 73.17  ? 79  LEU B CA  1 
ATOM   2427 C C   . LEU B 2 79  ? 128.352 134.734 109.598 1.00 74.31  ? 79  LEU B C   1 
ATOM   2428 O O   . LEU B 2 79  ? 127.806 135.757 109.181 1.00 84.12  ? 79  LEU B O   1 
ATOM   2429 C CB  . LEU B 2 79  ? 127.344 133.190 107.895 1.00 73.34  ? 79  LEU B CB  1 
ATOM   2430 C CG  . LEU B 2 79  ? 127.823 131.952 107.147 1.00 72.61  ? 79  LEU B CG  1 
ATOM   2431 C CD1 . LEU B 2 79  ? 127.681 132.164 105.654 1.00 72.05  ? 79  LEU B CD1 1 
ATOM   2432 C CD2 . LEU B 2 79  ? 129.255 131.655 107.500 1.00 75.96  ? 79  LEU B CD2 1 
ATOM   2433 N N   . ILE B 2 80  ? 129.495 134.756 110.271 1.00 56.31  ? 80  ILE B N   1 
ATOM   2434 C CA  . ILE B 2 80  ? 130.139 136.010 110.640 1.00 55.36  ? 80  ILE B CA  1 
ATOM   2435 C C   . ILE B 2 80  ? 131.289 136.278 109.685 1.00 65.71  ? 80  ILE B C   1 
ATOM   2436 O O   . ILE B 2 80  ? 132.173 135.431 109.504 1.00 78.12  ? 80  ILE B O   1 
ATOM   2437 C CB  . ILE B 2 80  ? 130.628 135.989 112.096 1.00 60.77  ? 80  ILE B CB  1 
ATOM   2438 C CG1 . ILE B 2 80  ? 129.456 135.776 113.048 1.00 68.82  ? 80  ILE B CG1 1 
ATOM   2439 C CG2 . ILE B 2 80  ? 131.308 137.295 112.433 1.00 63.26  ? 80  ILE B CG2 1 
ATOM   2440 C CD1 . ILE B 2 80  ? 129.883 135.538 114.471 1.00 74.06  ? 80  ILE B CD1 1 
ATOM   2441 N N   . ILE B 2 81  ? 131.274 137.455 109.074 1.00 68.17  ? 81  ILE B N   1 
ATOM   2442 C CA  . ILE B 2 81  ? 132.365 137.933 108.238 1.00 65.30  ? 81  ILE B CA  1 
ATOM   2443 C C   . ILE B 2 81  ? 133.181 138.911 109.067 1.00 65.76  ? 81  ILE B C   1 
ATOM   2444 O O   . ILE B 2 81  ? 132.665 139.953 109.492 1.00 76.67  ? 81  ILE B O   1 
ATOM   2445 C CB  . ILE B 2 81  ? 131.845 138.598 106.957 1.00 66.62  ? 81  ILE B CB  1 
ATOM   2446 C CG1 . ILE B 2 81  ? 130.815 137.701 106.275 1.00 68.49  ? 81  ILE B CG1 1 
ATOM   2447 C CG2 . ILE B 2 81  ? 132.997 138.908 106.022 1.00 67.85  ? 81  ILE B CG2 1 
ATOM   2448 C CD1 . ILE B 2 81  ? 130.508 138.101 104.859 1.00 75.96  ? 81  ILE B CD1 1 
ATOM   2449 N N   . TRP B 2 82  ? 134.448 138.569 109.276 1.00 67.35  ? 82  TRP B N   1 
ATOM   2450 C CA  . TRP B 2 82  ? 135.379 139.311 110.112 1.00 73.33  ? 82  TRP B CA  1 
ATOM   2451 C C   . TRP B 2 82  ? 136.388 140.055 109.252 1.00 76.46  ? 82  TRP B C   1 
ATOM   2452 O O   . TRP B 2 82  ? 136.816 139.557 108.205 1.00 85.23  ? 82  TRP B O   1 
ATOM   2453 C CB  . TRP B 2 82  ? 136.158 138.384 111.054 1.00 77.85  ? 82  TRP B CB  1 
ATOM   2454 C CG  . TRP B 2 82  ? 135.359 137.345 111.767 1.00 79.96  ? 82  TRP B CG  1 
ATOM   2455 C CD1 . TRP B 2 82  ? 134.780 136.239 111.224 1.00 81.29  ? 82  TRP B CD1 1 
ATOM   2456 C CD2 . TRP B 2 82  ? 135.089 137.291 113.170 1.00 77.66  ? 82  TRP B CD2 1 
ATOM   2457 N NE1 . TRP B 2 82  ? 134.147 135.510 112.198 1.00 81.30  ? 82  TRP B NE1 1 
ATOM   2458 C CE2 . TRP B 2 82  ? 134.323 136.136 113.403 1.00 76.72  ? 82  TRP B CE2 1 
ATOM   2459 C CE3 . TRP B 2 82  ? 135.412 138.113 114.250 1.00 77.55  ? 82  TRP B CE3 1 
ATOM   2460 C CZ2 . TRP B 2 82  ? 133.873 135.784 114.669 1.00 76.11  ? 82  TRP B CZ2 1 
ATOM   2461 C CZ3 . TRP B 2 82  ? 134.965 137.762 115.505 1.00 80.54  ? 82  TRP B CZ3 1 
ATOM   2462 C CH2 . TRP B 2 82  ? 134.204 136.608 115.705 1.00 79.42  ? 82  TRP B CH2 1 
ATOM   2463 N N   . ASP B 2 83  ? 136.773 141.242 109.711 1.00 72.37  ? 83  ASP B N   1 
ATOM   2464 C CA  . ASP B 2 83  ? 137.972 141.919 109.227 1.00 68.44  ? 83  ASP B CA  1 
ATOM   2465 C C   . ASP B 2 83  ? 139.116 141.451 110.115 1.00 75.85  ? 83  ASP B C   1 
ATOM   2466 O O   . ASP B 2 83  ? 139.302 141.952 111.225 1.00 85.83  ? 83  ASP B O   1 
ATOM   2467 C CB  . ASP B 2 83  ? 137.801 143.432 109.271 1.00 76.57  ? 83  ASP B CB  1 
ATOM   2468 C CG  . ASP B 2 83  ? 138.994 144.172 108.704 1.00 82.07  ? 83  ASP B CG  1 
ATOM   2469 O OD1 . ASP B 2 83  ? 139.895 143.517 108.143 1.00 86.01  ? 83  ASP B OD1 1 
ATOM   2470 O OD2 . ASP B 2 83  ? 139.035 145.413 108.824 1.00 83.42  ? 83  ASP B OD2 1 
ATOM   2471 N N   . SER B 2 84  ? 139.883 140.477 109.624 1.00 70.34  ? 84  SER B N   1 
ATOM   2472 C CA  . SER B 2 84  ? 140.891 139.833 110.457 1.00 69.61  ? 84  SER B CA  1 
ATOM   2473 C C   . SER B 2 84  ? 141.983 140.799 110.891 1.00 76.15  ? 84  SER B C   1 
ATOM   2474 O O   . SER B 2 84  ? 142.611 140.591 111.933 1.00 81.53  ? 84  SER B O   1 
ATOM   2475 C CB  . SER B 2 84  ? 141.511 138.661 109.709 1.00 72.84  ? 84  SER B CB  1 
ATOM   2476 O OG  . SER B 2 84  ? 142.361 139.125 108.677 1.00 76.49  ? 84  SER B OG  1 
ATOM   2477 N N   . TYR B 2 85  ? 142.241 141.842 110.101 1.00 72.43  ? 85  TYR B N   1 
ATOM   2478 C CA  . TYR B 2 85  ? 143.308 142.776 110.444 1.00 62.46  ? 85  TYR B CA  1 
ATOM   2479 C C   . TYR B 2 85  ? 143.005 143.514 111.740 1.00 60.75  ? 85  TYR B C   1 
ATOM   2480 O O   . TYR B 2 85  ? 143.894 143.697 112.579 1.00 70.72  ? 85  TYR B O   1 
ATOM   2481 C CB  . TYR B 2 85  ? 143.519 143.772 109.305 1.00 63.15  ? 85  TYR B CB  1 
ATOM   2482 C CG  . TYR B 2 85  ? 144.407 143.268 108.195 1.00 62.35  ? 85  TYR B CG  1 
ATOM   2483 C CD1 . TYR B 2 85  ? 144.677 141.918 108.054 1.00 66.55  ? 85  TYR B CD1 1 
ATOM   2484 C CD2 . TYR B 2 85  ? 144.966 144.144 107.281 1.00 66.16  ? 85  TYR B CD2 1 
ATOM   2485 C CE1 . TYR B 2 85  ? 145.485 141.457 107.038 1.00 70.25  ? 85  TYR B CE1 1 
ATOM   2486 C CE2 . TYR B 2 85  ? 145.773 143.693 106.263 1.00 66.66  ? 85  TYR B CE2 1 
ATOM   2487 C CZ  . TYR B 2 85  ? 146.029 142.349 106.145 1.00 70.63  ? 85  TYR B CZ  1 
ATOM   2488 O OH  . TYR B 2 85  ? 146.836 141.896 105.129 1.00 73.29  ? 85  TYR B OH  1 
ATOM   2489 N N   . THR B 2 86  ? 141.757 143.943 111.924 1.00 60.63  ? 86  THR B N   1 
ATOM   2490 C CA  . THR B 2 86  ? 141.378 144.760 113.069 1.00 67.15  ? 86  THR B CA  1 
ATOM   2491 C C   . THR B 2 86  ? 140.365 144.078 113.977 1.00 72.61  ? 86  THR B C   1 
ATOM   2492 O O   . THR B 2 86  ? 139.812 144.736 114.866 1.00 77.30  ? 86  THR B O   1 
ATOM   2493 C CB  . THR B 2 86  ? 140.817 146.104 112.598 1.00 74.67  ? 86  THR B CB  1 
ATOM   2494 O OG1 . THR B 2 86  ? 139.416 145.969 112.331 1.00 74.63  ? 86  THR B OG1 1 
ATOM   2495 C CG2 . THR B 2 86  ? 141.525 146.570 111.336 1.00 77.55  ? 86  THR B CG2 1 
ATOM   2496 N N   . THR B 2 87  ? 140.088 142.792 113.766 1.00 76.05  ? 87  THR B N   1 
ATOM   2497 C CA  . THR B 2 87  ? 139.140 141.986 114.532 1.00 75.53  ? 87  THR B CA  1 
ATOM   2498 C C   . THR B 2 87  ? 137.709 142.493 114.385 1.00 74.83  ? 87  THR B C   1 
ATOM   2499 O O   . THR B 2 87  ? 136.796 141.920 114.987 1.00 75.54  ? 87  THR B O   1 
ATOM   2500 C CB  . THR B 2 87  ? 139.509 141.914 116.023 1.00 80.18  ? 87  THR B CB  1 
ATOM   2501 O OG1 . THR B 2 87  ? 140.934 141.883 116.155 1.00 84.74  ? 87  THR B OG1 1 
ATOM   2502 C CG2 . THR B 2 87  ? 138.950 140.651 116.662 1.00 81.62  ? 87  THR B CG2 1 
ATOM   2503 N N   . ASN B 2 88  ? 137.481 143.540 113.597 1.00 75.86  ? 88  ASN B N   1 
ATOM   2504 C CA  . ASN B 2 88  ? 136.131 144.036 113.378 1.00 71.18  ? 88  ASN B CA  1 
ATOM   2505 C C   . ASN B 2 88  ? 135.292 142.983 112.672 1.00 75.27  ? 88  ASN B C   1 
ATOM   2506 O O   . ASN B 2 88  ? 135.781 142.253 111.806 1.00 85.87  ? 88  ASN B O   1 
ATOM   2507 C CB  . ASN B 2 88  ? 136.168 145.318 112.552 1.00 70.05  ? 88  ASN B CB  1 
ATOM   2508 C CG  . ASN B 2 88  ? 136.605 146.515 113.360 1.00 80.80  ? 88  ASN B CG  1 
ATOM   2509 O OD1 . ASN B 2 88  ? 136.672 146.459 114.586 1.00 82.69  ? 88  ASN B OD1 1 
ATOM   2510 N ND2 . ASN B 2 88  ? 136.915 147.609 112.676 1.00 81.91  ? 88  ASN B ND2 1 
ATOM   2511 N N   . LYS B 2 89  ? 134.023 142.902 113.047 1.00 69.73  ? 89  LYS B N   1 
ATOM   2512 C CA  . LYS B 2 89  ? 133.107 141.919 112.481 1.00 73.99  ? 89  LYS B CA  1 
ATOM   2513 C C   . LYS B 2 89  ? 132.243 142.628 111.448 1.00 78.16  ? 89  LYS B C   1 
ATOM   2514 O O   . LYS B 2 89  ? 131.314 143.361 111.793 1.00 82.02  ? 89  LYS B O   1 
ATOM   2515 C CB  . LYS B 2 89  ? 132.288 141.258 113.581 1.00 74.59  ? 89  LYS B CB  1 
ATOM   2516 C CG  . LYS B 2 89  ? 133.185 140.618 114.622 1.00 81.54  ? 89  LYS B CG  1 
ATOM   2517 C CD  . LYS B 2 89  ? 132.542 140.351 115.974 1.00 78.81  ? 89  LYS B CD  1 
ATOM   2518 C CE  . LYS B 2 89  ? 131.307 139.474 115.881 1.00 79.03  ? 89  LYS B CE  1 
ATOM   2519 N NZ  . LYS B 2 89  ? 130.095 140.188 115.430 1.00 77.05  ? 89  LYS B NZ  1 
ATOM   2520 N N   . VAL B 2 90  ? 132.566 142.406 110.174 1.00 73.35  ? 90  VAL B N   1 
ATOM   2521 C CA  . VAL B 2 90  ? 131.909 143.129 109.091 1.00 69.12  ? 90  VAL B CA  1 
ATOM   2522 C C   . VAL B 2 90  ? 130.438 142.751 109.004 1.00 69.81  ? 90  VAL B C   1 
ATOM   2523 O O   . VAL B 2 90  ? 129.565 143.618 108.887 1.00 77.77  ? 90  VAL B O   1 
ATOM   2524 C CB  . VAL B 2 90  ? 132.635 142.865 107.762 1.00 69.01  ? 90  VAL B CB  1 
ATOM   2525 C CG1 . VAL B 2 90  ? 132.118 143.791 106.692 1.00 72.43  ? 90  VAL B CG1 1 
ATOM   2526 C CG2 . VAL B 2 90  ? 134.128 143.039 107.939 1.00 68.27  ? 90  VAL B CG2 1 
ATOM   2527 N N   . HIS B 2 91  ? 130.139 141.458 109.060 1.00 67.95  ? 91  HIS B N   1 
ATOM   2528 C CA  . HIS B 2 91  ? 128.780 140.995 108.816 1.00 69.97  ? 91  HIS B CA  1 
ATOM   2529 C C   . HIS B 2 91  ? 128.415 139.881 109.782 1.00 72.97  ? 91  HIS B C   1 
ATOM   2530 O O   . HIS B 2 91  ? 129.279 139.143 110.255 1.00 84.53  ? 91  HIS B O   1 
ATOM   2531 C CB  . HIS B 2 91  ? 128.606 140.485 107.381 1.00 71.31  ? 91  HIS B CB  1 
ATOM   2532 C CG  . HIS B 2 91  ? 128.489 141.571 106.359 1.00 68.63  ? 91  HIS B CG  1 
ATOM   2533 N ND1 . HIS B 2 91  ? 129.415 141.749 105.355 1.00 69.42  ? 91  HIS B ND1 1 
ATOM   2534 C CD2 . HIS B 2 91  ? 127.544 142.522 106.172 1.00 66.08  ? 91  HIS B CD2 1 
ATOM   2535 C CE1 . HIS B 2 91  ? 129.052 142.770 104.600 1.00 71.99  ? 91  HIS B CE1 1 
ATOM   2536 N NE2 . HIS B 2 91  ? 127.920 143.256 105.075 1.00 71.38  ? 91  HIS B NE2 1 
ATOM   2537 N N   . ALA B 2 92  ? 127.115 139.752 110.049 1.00 61.35  ? 92  ALA B N   1 
ATOM   2538 C CA  . ALA B 2 92  ? 126.569 138.616 110.793 1.00 66.24  ? 92  ALA B CA  1 
ATOM   2539 C C   . ALA B 2 92  ? 125.269 138.213 110.102 1.00 72.54  ? 92  ALA B C   1 
ATOM   2540 O O   . ALA B 2 92  ? 124.196 138.726 110.427 1.00 80.75  ? 92  ALA B O   1 
ATOM   2541 C CB  . ALA B 2 92  ? 126.348 138.954 112.257 1.00 67.60  ? 92  ALA B CB  1 
ATOM   2542 N N   . ILE B 2 93  ? 125.374 137.295 109.147 1.00 68.18  ? 93  ILE B N   1 
ATOM   2543 C CA  . ILE B 2 93  ? 124.219 136.815 108.396 1.00 67.61  ? 93  ILE B CA  1 
ATOM   2544 C C   . ILE B 2 93  ? 123.487 135.771 109.229 1.00 68.10  ? 93  ILE B C   1 
ATOM   2545 O O   . ILE B 2 93  ? 124.090 134.764 109.621 1.00 73.96  ? 93  ILE B O   1 
ATOM   2546 C CB  . ILE B 2 93  ? 124.642 136.236 107.039 1.00 75.92  ? 93  ILE B CB  1 
ATOM   2547 C CG1 . ILE B 2 93  ? 125.233 137.332 106.153 1.00 76.40  ? 93  ILE B CG1 1 
ATOM   2548 C CG2 . ILE B 2 93  ? 123.461 135.571 106.356 1.00 78.25  ? 93  ILE B CG2 1 
ATOM   2549 C CD1 . ILE B 2 93  ? 126.738 137.343 106.126 1.00 76.93  ? 93  ILE B CD1 1 
ATOM   2550 N N   . PRO B 2 94  ? 122.207 135.960 109.523 1.00 70.16  ? 94  PRO B N   1 
ATOM   2551 C CA  . PRO B 2 94  ? 121.450 134.948 110.272 1.00 68.50  ? 94  PRO B CA  1 
ATOM   2552 C C   . PRO B 2 94  ? 120.993 133.826 109.353 1.00 78.72  ? 94  PRO B C   1 
ATOM   2553 O O   . PRO B 2 94  ? 120.168 134.029 108.458 1.00 81.42  ? 94  PRO B O   1 
ATOM   2554 C CB  . PRO B 2 94  ? 120.269 135.748 110.836 1.00 68.50  ? 94  PRO B CB  1 
ATOM   2555 C CG  . PRO B 2 94  ? 120.071 136.859 109.870 1.00 74.88  ? 94  PRO B CG  1 
ATOM   2556 C CD  . PRO B 2 94  ? 121.400 137.155 109.223 1.00 76.07  ? 94  PRO B CD  1 
ATOM   2557 N N   . LEU B 2 95  ? 121.533 132.632 109.575 1.00 80.55  ? 95  LEU B N   1 
ATOM   2558 C CA  . LEU B 2 95  ? 121.221 131.496 108.720 1.00 72.11  ? 95  LEU B CA  1 
ATOM   2559 C C   . LEU B 2 95  ? 119.793 131.020 108.950 1.00 76.60  ? 95  LEU B C   1 
ATOM   2560 O O   . LEU B 2 95  ? 119.278 131.065 110.069 1.00 82.39  ? 95  LEU B O   1 
ATOM   2561 C CB  . LEU B 2 95  ? 122.196 130.355 108.983 1.00 69.74  ? 95  LEU B CB  1 
ATOM   2562 C CG  . LEU B 2 95  ? 123.666 130.756 108.987 1.00 73.66  ? 95  LEU B CG  1 
ATOM   2563 C CD1 . LEU B 2 95  ? 124.541 129.558 109.295 1.00 76.48  ? 95  LEU B CD1 1 
ATOM   2564 C CD2 . LEU B 2 95  ? 124.040 131.385 107.661 1.00 76.91  ? 95  LEU B CD2 1 
ATOM   2565 N N   . ARG B 2 96  ? 119.152 130.563 107.873 1.00 85.05  ? 96  ARG B N   1 
ATOM   2566 C CA  . ARG B 2 96  ? 117.813 130.000 107.997 1.00 86.64  ? 96  ARG B CA  1 
ATOM   2567 C C   . ARG B 2 96  ? 117.825 128.731 108.837 1.00 90.32  ? 96  ARG B C   1 
ATOM   2568 O O   . ARG B 2 96  ? 116.933 128.519 109.666 1.00 94.77  ? 96  ARG B O   1 
ATOM   2569 C CB  . ARG B 2 96  ? 117.228 129.727 106.614 1.00 84.13  ? 96  ARG B CB  1 
ATOM   2570 C CG  . ARG B 2 96  ? 115.719 129.590 106.600 1.00 85.58  ? 96  ARG B CG  1 
ATOM   2571 C CD  . ARG B 2 96  ? 115.050 130.897 106.222 1.00 92.23  ? 96  ARG B CD  1 
ATOM   2572 N NE  . ARG B 2 96  ? 115.015 131.095 104.778 1.00 96.98  ? 96  ARG B NE  1 
ATOM   2573 C CZ  . ARG B 2 96  ? 115.741 131.995 104.129 1.00 94.65  ? 96  ARG B CZ  1 
ATOM   2574 N NH1 . ARG B 2 96  ? 116.575 132.799 104.767 1.00 92.52  ? 96  ARG B NH1 1 
ATOM   2575 N NH2 . ARG B 2 96  ? 115.626 132.092 102.808 1.00 89.63  ? 96  ARG B NH2 1 
ATOM   2576 N N   . SER B 2 97  ? 118.823 127.877 108.637 1.00 82.74  ? 97  SER B N   1 
ATOM   2577 C CA  . SER B 2 97  ? 119.011 126.674 109.435 1.00 77.06  ? 97  SER B CA  1 
ATOM   2578 C C   . SER B 2 97  ? 120.313 126.793 110.211 1.00 78.00  ? 97  SER B C   1 
ATOM   2579 O O   . SER B 2 97  ? 121.368 127.045 109.622 1.00 84.99  ? 97  SER B O   1 
ATOM   2580 C CB  . SER B 2 97  ? 119.035 125.426 108.553 1.00 79.86  ? 97  SER B CB  1 
ATOM   2581 O OG  . SER B 2 97  ? 120.236 125.361 107.806 1.00 81.14  ? 97  SER B OG  1 
ATOM   2582 N N   . SER B 2 98  ? 120.237 126.603 111.527 1.00 83.04  ? 98  SER B N   1 
ATOM   2583 C CA  . SER B 2 98  ? 121.415 126.742 112.373 1.00 85.43  ? 98  SER B CA  1 
ATOM   2584 C C   . SER B 2 98  ? 122.431 125.630 112.163 1.00 85.99  ? 98  SER B C   1 
ATOM   2585 O O   . SER B 2 98  ? 123.559 125.750 112.650 1.00 86.73  ? 98  SER B O   1 
ATOM   2586 C CB  . SER B 2 98  ? 120.999 126.785 113.843 1.00 84.25  ? 98  SER B CB  1 
ATOM   2587 O OG  . SER B 2 98  ? 120.378 125.573 114.229 1.00 88.02  ? 98  SER B OG  1 
ATOM   2588 N N   . TRP B 2 99  ? 122.069 124.563 111.459 1.00 83.49  ? 99  TRP B N   1 
ATOM   2589 C CA  . TRP B 2 99  ? 122.961 123.427 111.247 1.00 80.96  ? 99  TRP B CA  1 
ATOM   2590 C C   . TRP B 2 99  ? 123.807 123.691 110.012 1.00 79.43  ? 99  TRP B C   1 
ATOM   2591 O O   . TRP B 2 99  ? 123.362 123.487 108.881 1.00 88.52  ? 99  TRP B O   1 
ATOM   2592 C CB  . TRP B 2 99  ? 122.160 122.138 111.126 1.00 81.15  ? 99  TRP B CB  1 
ATOM   2593 C CG  . TRP B 2 99  ? 121.358 121.892 112.344 1.00 77.88  ? 99  TRP B CG  1 
ATOM   2594 C CD1 . TRP B 2 99  ? 120.004 121.825 112.441 1.00 76.31  ? 99  TRP B CD1 1 
ATOM   2595 C CD2 . TRP B 2 99  ? 121.868 121.711 113.664 1.00 80.82  ? 99  TRP B CD2 1 
ATOM   2596 N NE1 . TRP B 2 99  ? 119.638 121.601 113.745 1.00 75.22  ? 99  TRP B NE1 1 
ATOM   2597 C CE2 . TRP B 2 99  ? 120.770 121.528 114.513 1.00 78.74  ? 99  TRP B CE2 1 
ATOM   2598 C CE3 . TRP B 2 99  ? 123.153 121.680 114.209 1.00 85.16  ? 99  TRP B CE3 1 
ATOM   2599 C CZ2 . TRP B 2 99  ? 120.917 121.314 115.875 1.00 81.79  ? 99  TRP B CZ2 1 
ATOM   2600 C CZ3 . TRP B 2 99  ? 123.294 121.472 115.560 1.00 83.97  ? 99  TRP B CZ3 1 
ATOM   2601 C CH2 . TRP B 2 99  ? 122.184 121.291 116.379 1.00 82.77  ? 99  TRP B CH2 1 
ATOM   2602 N N   . VAL B 2 100 ? 125.034 124.147 110.234 1.00 69.24  ? 100 VAL B N   1 
ATOM   2603 C CA  . VAL B 2 100 ? 125.963 124.473 109.163 1.00 71.70  ? 100 VAL B CA  1 
ATOM   2604 C C   . VAL B 2 100 ? 127.287 123.780 109.443 1.00 75.60  ? 100 VAL B C   1 
ATOM   2605 O O   . VAL B 2 100 ? 127.783 123.808 110.574 1.00 86.60  ? 100 VAL B O   1 
ATOM   2606 C CB  . VAL B 2 100 ? 126.160 125.993 109.020 1.00 71.84  ? 100 VAL B CB  1 
ATOM   2607 C CG1 . VAL B 2 100 ? 126.603 126.607 110.333 1.00 77.51  ? 100 VAL B CG1 1 
ATOM   2608 C CG2 . VAL B 2 100 ? 127.183 126.277 107.950 1.00 75.84  ? 100 VAL B CG2 1 
ATOM   2609 N N   . MET B 2 101 ? 127.844 123.133 108.422 1.00 84.12  ? 101 MET B N   1 
ATOM   2610 C CA  . MET B 2 101 ? 129.163 122.539 108.540 1.00 89.70  ? 101 MET B CA  1 
ATOM   2611 C C   . MET B 2 101 ? 130.101 122.921 107.407 1.00 90.72  ? 101 MET B C   1 
ATOM   2612 O O   . MET B 2 101 ? 131.208 122.377 107.336 1.00 93.14  ? 101 MET B O   1 
ATOM   2613 C CB  . MET B 2 101 ? 129.067 121.011 108.630 1.00 89.78  ? 101 MET B CB  1 
ATOM   2614 C CG  . MET B 2 101 ? 127.701 120.495 109.021 1.00 90.69  ? 101 MET B CG  1 
ATOM   2615 S SD  . MET B 2 101 ? 127.784 118.756 109.449 1.00 100.69 ? 101 MET B SD  1 
ATOM   2616 C CE  . MET B 2 101 ? 128.055 118.074 107.830 1.00 91.81  ? 101 MET B CE  1 
ATOM   2617 N N   . THR B 2 102 ? 129.702 123.833 106.526 1.00 81.18  ? 102 THR B N   1 
ATOM   2618 C CA  . THR B 2 102 ? 130.606 124.327 105.503 1.00 80.22  ? 102 THR B CA  1 
ATOM   2619 C C   . THR B 2 102 ? 130.247 125.762 105.155 1.00 83.91  ? 102 THR B C   1 
ATOM   2620 O O   . THR B 2 102 ? 129.086 126.170 105.238 1.00 89.83  ? 102 THR B O   1 
ATOM   2621 C CB  . THR B 2 102 ? 130.581 123.463 104.243 1.00 86.77  ? 102 THR B CB  1 
ATOM   2622 O OG1 . THR B 2 102 ? 131.516 123.989 103.294 1.00 93.50  ? 102 THR B OG1 1 
ATOM   2623 C CG2 . THR B 2 102 ? 129.195 123.446 103.630 1.00 85.56  ? 102 THR B CG2 1 
ATOM   2624 N N   . CYS B 2 103 ? 131.268 126.523 104.772 1.00 77.28  ? 103 CYS B N   1 
ATOM   2625 C CA  . CYS B 2 103 ? 131.099 127.894 104.323 1.00 73.09  ? 103 CYS B CA  1 
ATOM   2626 C C   . CYS B 2 103 ? 132.213 128.213 103.341 1.00 75.26  ? 103 CYS B C   1 
ATOM   2627 O O   . CYS B 2 103 ? 133.294 127.621 103.398 1.00 77.50  ? 103 CYS B O   1 
ATOM   2628 C CB  . CYS B 2 103 ? 131.109 128.879 105.495 1.00 72.88  ? 103 CYS B CB  1 
ATOM   2629 S SG  . CYS B 2 103 ? 132.720 129.082 106.268 1.00 90.73  ? 103 CYS B SG  1 
ATOM   2630 N N   . ALA B 2 104 ? 131.944 129.150 102.438 1.00 72.33  ? 104 ALA B N   1 
ATOM   2631 C CA  . ALA B 2 104 ? 132.913 129.494 101.411 1.00 70.48  ? 104 ALA B CA  1 
ATOM   2632 C C   . ALA B 2 104 ? 132.807 130.972 101.077 1.00 72.38  ? 104 ALA B C   1 
ATOM   2633 O O   . ALA B 2 104 ? 131.725 131.560 101.128 1.00 81.76  ? 104 ALA B O   1 
ATOM   2634 C CB  . ALA B 2 104 ? 132.709 128.659 100.145 1.00 69.96  ? 104 ALA B CB  1 
ATOM   2635 N N   . TYR B 2 105 ? 133.946 131.560 100.732 1.00 71.94  ? 105 TYR B N   1 
ATOM   2636 C CA  . TYR B 2 105 ? 134.022 132.926 100.238 1.00 70.38  ? 105 TYR B CA  1 
ATOM   2637 C C   . TYR B 2 105 ? 134.208 132.888 98.730  1.00 71.38  ? 105 TYR B C   1 
ATOM   2638 O O   . TYR B 2 105 ? 135.136 132.242 98.234  1.00 76.09  ? 105 TYR B O   1 
ATOM   2639 C CB  . TYR B 2 105 ? 135.180 133.688 100.884 1.00 71.12  ? 105 TYR B CB  1 
ATOM   2640 C CG  . TYR B 2 105 ? 134.817 135.079 101.336 1.00 70.25  ? 105 TYR B CG  1 
ATOM   2641 C CD1 . TYR B 2 105 ? 134.150 135.950 100.491 1.00 72.00  ? 105 TYR B CD1 1 
ATOM   2642 C CD2 . TYR B 2 105 ? 135.157 135.529 102.599 1.00 70.33  ? 105 TYR B CD2 1 
ATOM   2643 C CE1 . TYR B 2 105 ? 133.817 137.222 100.897 1.00 74.37  ? 105 TYR B CE1 1 
ATOM   2644 C CE2 . TYR B 2 105 ? 134.830 136.800 103.012 1.00 68.34  ? 105 TYR B CE2 1 
ATOM   2645 C CZ  . TYR B 2 105 ? 134.160 137.641 102.158 1.00 67.82  ? 105 TYR B CZ  1 
ATOM   2646 O OH  . TYR B 2 105 ? 133.833 138.912 102.566 1.00 74.96  ? 105 TYR B OH  1 
ATOM   2647 N N   . ALA B 2 106 ? 133.327 133.570 98.008  1.00 67.40  ? 106 ALA B N   1 
ATOM   2648 C CA  . ALA B 2 106 ? 133.470 133.647 96.567  1.00 65.36  ? 106 ALA B CA  1 
ATOM   2649 C C   . ALA B 2 106 ? 134.764 134.378 96.217  1.00 67.58  ? 106 ALA B C   1 
ATOM   2650 O O   . ALA B 2 106 ? 135.191 135.278 96.946  1.00 79.74  ? 106 ALA B O   1 
ATOM   2651 C CB  . ALA B 2 106 ? 132.273 134.362 95.949  1.00 68.70  ? 106 ALA B CB  1 
ATOM   2652 N N   . PRO B 2 107 ? 135.421 133.999 95.118  1.00 63.84  ? 107 PRO B N   1 
ATOM   2653 C CA  . PRO B 2 107 ? 136.690 134.658 94.772  1.00 65.80  ? 107 PRO B CA  1 
ATOM   2654 C C   . PRO B 2 107 ? 136.556 136.156 94.583  1.00 69.65  ? 107 PRO B C   1 
ATOM   2655 O O   . PRO B 2 107 ? 137.473 136.907 94.935  1.00 70.11  ? 107 PRO B O   1 
ATOM   2656 C CB  . PRO B 2 107 ? 137.106 133.952 93.475  1.00 67.52  ? 107 PRO B CB  1 
ATOM   2657 C CG  . PRO B 2 107 ? 136.394 132.650 93.510  1.00 68.05  ? 107 PRO B CG  1 
ATOM   2658 C CD  . PRO B 2 107 ? 135.083 132.931 94.167  1.00 72.16  ? 107 PRO B CD  1 
ATOM   2659 N N   . SER B 2 108 ? 135.432 136.616 94.037  1.00 73.84  ? 108 SER B N   1 
ATOM   2660 C CA  . SER B 2 108 ? 135.201 138.045 93.898  1.00 74.34  ? 108 SER B CA  1 
ATOM   2661 C C   . SER B 2 108 ? 134.838 138.705 95.218  1.00 77.92  ? 108 SER B C   1 
ATOM   2662 O O   . SER B 2 108 ? 134.912 139.934 95.322  1.00 84.46  ? 108 SER B O   1 
ATOM   2663 C CB  . SER B 2 108 ? 134.091 138.303 92.881  1.00 76.43  ? 108 SER B CB  1 
ATOM   2664 O OG  . SER B 2 108 ? 132.818 138.119 93.471  1.00 80.22  ? 108 SER B OG  1 
ATOM   2665 N N   . GLY B 2 109 ? 134.450 137.924 96.221  1.00 75.45  ? 109 GLY B N   1 
ATOM   2666 C CA  . GLY B 2 109 ? 134.024 138.467 97.489  1.00 73.06  ? 109 GLY B CA  1 
ATOM   2667 C C   . GLY B 2 109 ? 132.598 138.959 97.522  1.00 74.05  ? 109 GLY B C   1 
ATOM   2668 O O   . GLY B 2 109 ? 132.170 139.492 98.552  1.00 77.65  ? 109 GLY B O   1 
ATOM   2669 N N   . ASN B 2 110 ? 131.847 138.805 96.434  1.00 71.63  ? 110 ASN B N   1 
ATOM   2670 C CA  . ASN B 2 110 ? 130.475 139.285 96.389  1.00 76.97  ? 110 ASN B CA  1 
ATOM   2671 C C   . ASN B 2 110 ? 129.479 138.314 97.004  1.00 85.59  ? 110 ASN B C   1 
ATOM   2672 O O   . ASN B 2 110 ? 128.344 138.716 97.283  1.00 90.00  ? 110 ASN B O   1 
ATOM   2673 C CB  . ASN B 2 110 ? 130.068 139.574 94.945  1.00 77.53  ? 110 ASN B CB  1 
ATOM   2674 C CG  . ASN B 2 110 ? 131.040 140.490 94.240  1.00 82.57  ? 110 ASN B CG  1 
ATOM   2675 O OD1 . ASN B 2 110 ? 131.468 140.216 93.121  1.00 86.48  ? 110 ASN B OD1 1 
ATOM   2676 N ND2 . ASN B 2 110 ? 131.399 141.587 94.894  1.00 83.78  ? 110 ASN B ND2 1 
ATOM   2677 N N   . TYR B 2 111 ? 129.863 137.060 97.226  1.00 77.72  ? 111 TYR B N   1 
ATOM   2678 C CA  . TYR B 2 111 ? 128.940 136.057 97.732  1.00 74.05  ? 111 TYR B CA  1 
ATOM   2679 C C   . TYR B 2 111 ? 129.634 135.200 98.778  1.00 75.16  ? 111 TYR B C   1 
ATOM   2680 O O   . TYR B 2 111 ? 130.859 135.076 98.798  1.00 74.81  ? 111 TYR B O   1 
ATOM   2681 C CB  . TYR B 2 111 ? 128.402 135.159 96.611  1.00 69.25  ? 111 TYR B CB  1 
ATOM   2682 C CG  . TYR B 2 111 ? 127.676 135.896 95.514  1.00 63.35  ? 111 TYR B CG  1 
ATOM   2683 C CD1 . TYR B 2 111 ? 126.337 136.223 95.640  1.00 68.29  ? 111 TYR B CD1 1 
ATOM   2684 C CD2 . TYR B 2 111 ? 128.328 136.256 94.348  1.00 70.91  ? 111 TYR B CD2 1 
ATOM   2685 C CE1 . TYR B 2 111 ? 125.670 136.891 94.640  1.00 72.98  ? 111 TYR B CE1 1 
ATOM   2686 C CE2 . TYR B 2 111 ? 127.670 136.925 93.342  1.00 75.39  ? 111 TYR B CE2 1 
ATOM   2687 C CZ  . TYR B 2 111 ? 126.341 137.241 93.493  1.00 71.64  ? 111 TYR B CZ  1 
ATOM   2688 O OH  . TYR B 2 111 ? 125.680 137.909 92.491  1.00 71.01  ? 111 TYR B OH  1 
ATOM   2689 N N   . VAL B 2 112 ? 128.826 134.614 99.655  1.00 79.39  ? 112 VAL B N   1 
ATOM   2690 C CA  . VAL B 2 112 ? 129.297 133.621 100.613 1.00 69.07  ? 112 VAL B CA  1 
ATOM   2691 C C   . VAL B 2 112 ? 128.365 132.420 100.565 1.00 75.66  ? 112 VAL B C   1 
ATOM   2692 O O   . VAL B 2 112 ? 127.141 132.571 100.501 1.00 83.06  ? 112 VAL B O   1 
ATOM   2693 C CB  . VAL B 2 112 ? 129.392 134.185 102.046 1.00 69.18  ? 112 VAL B CB  1 
ATOM   2694 C CG1 . VAL B 2 112 ? 130.512 135.198 102.137 1.00 76.25  ? 112 VAL B CG1 1 
ATOM   2695 C CG2 . VAL B 2 112 ? 128.081 134.808 102.469 1.00 77.93  ? 112 VAL B CG2 1 
ATOM   2696 N N   . ALA B 2 113 ? 128.944 131.225 100.582 1.00 78.42  ? 113 ALA B N   1 
ATOM   2697 C CA  . ALA B 2 113 ? 128.175 129.992 100.553 1.00 75.16  ? 113 ALA B CA  1 
ATOM   2698 C C   . ALA B 2 113 ? 128.027 129.442 101.962 1.00 77.32  ? 113 ALA B C   1 
ATOM   2699 O O   . ALA B 2 113 ? 128.940 129.553 102.782 1.00 82.18  ? 113 ALA B O   1 
ATOM   2700 C CB  . ALA B 2 113 ? 128.838 128.945 99.659  1.00 77.20  ? 113 ALA B CB  1 
ATOM   2701 N N   . CYS B 2 114 ? 126.867 128.860 102.240 1.00 84.00  ? 114 CYS B N   1 
ATOM   2702 C CA  . CYS B 2 114 ? 126.598 128.223 103.517 1.00 75.71  ? 114 CYS B CA  1 
ATOM   2703 C C   . CYS B 2 114 ? 125.908 126.894 103.264 1.00 77.86  ? 114 CYS B C   1 
ATOM   2704 O O   . CYS B 2 114 ? 125.007 126.806 102.430 1.00 92.83  ? 114 CYS B O   1 
ATOM   2705 C CB  . CYS B 2 114 ? 125.723 129.109 104.398 1.00 85.94  ? 114 CYS B CB  1 
ATOM   2706 S SG  . CYS B 2 114 ? 126.049 128.953 106.150 1.00 108.15 ? 114 CYS B SG  1 
ATOM   2707 N N   . GLY B 2 115 ? 126.326 125.863 103.977 1.00 75.47  ? 115 GLY B N   1 
ATOM   2708 C CA  . GLY B 2 115 ? 125.752 124.546 103.774 1.00 83.08  ? 115 GLY B CA  1 
ATOM   2709 C C   . GLY B 2 115 ? 125.794 123.736 105.044 1.00 82.75  ? 115 GLY B C   1 
ATOM   2710 O O   . GLY B 2 115 ? 126.678 123.912 105.887 1.00 90.50  ? 115 GLY B O   1 
ATOM   2711 N N   . GLY B 2 116 ? 124.835 122.828 105.176 1.00 76.82  ? 116 GLY B N   1 
ATOM   2712 C CA  . GLY B 2 116 ? 124.769 122.012 106.367 1.00 82.71  ? 116 GLY B CA  1 
ATOM   2713 C C   . GLY B 2 116 ? 123.850 120.819 106.243 1.00 83.27  ? 116 GLY B C   1 
ATOM   2714 O O   . GLY B 2 116 ? 123.756 120.199 105.180 1.00 89.77  ? 116 GLY B O   1 
ATOM   2715 N N   . LEU B 2 117 ? 123.164 120.490 107.333 1.00 81.23  ? 117 LEU B N   1 
ATOM   2716 C CA  . LEU B 2 117 ? 122.313 119.312 107.372 1.00 79.37  ? 117 LEU B CA  1 
ATOM   2717 C C   . LEU B 2 117 ? 120.952 119.543 106.736 1.00 84.05  ? 117 LEU B C   1 
ATOM   2718 O O   . LEU B 2 117 ? 120.138 118.614 106.701 1.00 92.81  ? 117 LEU B O   1 
ATOM   2719 C CB  . LEU B 2 117 ? 122.144 118.846 108.816 1.00 82.40  ? 117 LEU B CB  1 
ATOM   2720 C CG  . LEU B 2 117 ? 123.429 118.344 109.471 1.00 83.96  ? 117 LEU B CG  1 
ATOM   2721 C CD1 . LEU B 2 117 ? 123.395 118.560 110.969 1.00 84.48  ? 117 LEU B CD1 1 
ATOM   2722 C CD2 . LEU B 2 117 ? 123.641 116.881 109.152 1.00 86.35  ? 117 LEU B CD2 1 
ATOM   2723 N N   . ASP B 2 118 ? 120.683 120.748 106.241 1.00 85.17  ? 118 ASP B N   1 
ATOM   2724 C CA  . ASP B 2 118 ? 119.441 121.019 105.532 1.00 85.61  ? 118 ASP B CA  1 
ATOM   2725 C C   . ASP B 2 118 ? 119.496 120.595 104.072 1.00 86.73  ? 118 ASP B C   1 
ATOM   2726 O O   . ASP B 2 118 ? 118.493 120.742 103.366 1.00 90.90  ? 118 ASP B O   1 
ATOM   2727 C CB  . ASP B 2 118 ? 119.099 122.505 105.623 1.00 90.44  ? 118 ASP B CB  1 
ATOM   2728 C CG  . ASP B 2 118 ? 120.196 123.388 105.066 1.00 97.94  ? 118 ASP B CG  1 
ATOM   2729 O OD1 . ASP B 2 118 ? 121.361 122.940 105.035 1.00 99.47  ? 118 ASP B OD1 1 
ATOM   2730 O OD2 . ASP B 2 118 ? 119.894 124.530 104.659 1.00 101.66 ? 118 ASP B OD2 1 
ATOM   2731 N N   . ASN B 2 119 ? 120.640 120.089 103.611 1.00 84.43  ? 119 ASN B N   1 
ATOM   2732 C CA  . ASN B 2 119 ? 120.853 119.645 102.236 1.00 88.06  ? 119 ASN B CA  1 
ATOM   2733 C C   . ASN B 2 119 ? 120.669 120.773 101.231 1.00 97.30  ? 119 ASN B C   1 
ATOM   2734 O O   . ASN B 2 119 ? 120.393 120.521 100.054 1.00 103.53 ? 119 ASN B O   1 
ATOM   2735 C CB  . ASN B 2 119 ? 119.936 118.473 101.868 1.00 87.20  ? 119 ASN B CB  1 
ATOM   2736 C CG  . ASN B 2 119 ? 119.849 117.432 102.960 1.00 93.75  ? 119 ASN B CG  1 
ATOM   2737 O OD1 . ASN B 2 119 ? 118.781 116.885 103.221 1.00 95.24  ? 119 ASN B OD1 1 
ATOM   2738 N ND2 . ASN B 2 119 ? 120.964 117.175 103.625 1.00 96.12  ? 119 ASN B ND2 1 
ATOM   2739 N N   . ILE B 2 120 ? 120.815 122.018 101.672 1.00 83.08  ? 120 ILE B N   1 
ATOM   2740 C CA  . ILE B 2 120 ? 120.600 123.187 100.830 1.00 77.46  ? 120 ILE B CA  1 
ATOM   2741 C C   . ILE B 2 120 ? 121.825 124.079 100.928 1.00 83.73  ? 120 ILE B C   1 
ATOM   2742 O O   . ILE B 2 120 ? 122.296 124.374 102.031 1.00 86.98  ? 120 ILE B O   1 
ATOM   2743 C CB  . ILE B 2 120 ? 119.333 123.958 101.244 1.00 77.39  ? 120 ILE B CB  1 
ATOM   2744 C CG1 . ILE B 2 120 ? 118.084 123.157 100.880 1.00 80.67  ? 120 ILE B CG1 1 
ATOM   2745 C CG2 . ILE B 2 120 ? 119.298 125.324 100.587 1.00 83.82  ? 120 ILE B CG2 1 
ATOM   2746 C CD1 . ILE B 2 120 ? 116.794 123.851 101.238 1.00 83.13  ? 120 ILE B CD1 1 
ATOM   2747 N N   . CYS B 2 121 ? 122.343 124.504 99.779  1.00 84.67  ? 121 CYS B N   1 
ATOM   2748 C CA  . CYS B 2 121 ? 123.456 125.445 99.731  1.00 75.00  ? 121 CYS B CA  1 
ATOM   2749 C C   . CYS B 2 121 ? 122.887 126.847 99.551  1.00 77.54  ? 121 CYS B C   1 
ATOM   2750 O O   . CYS B 2 121 ? 122.337 127.171 98.496  1.00 85.47  ? 121 CYS B O   1 
ATOM   2751 C CB  . CYS B 2 121 ? 124.418 125.092 98.602  1.00 75.98  ? 121 CYS B CB  1 
ATOM   2752 S SG  . CYS B 2 121 ? 125.992 125.956 98.681  1.00 80.75  ? 121 CYS B SG  1 
ATOM   2753 N N   . SER B 2 122 ? 123.005 127.671 100.584 1.00 79.53  ? 122 SER B N   1 
ATOM   2754 C CA  . SER B 2 122 ? 122.510 129.037 100.547 1.00 79.93  ? 122 SER B CA  1 
ATOM   2755 C C   . SER B 2 122 ? 123.636 129.966 100.113 1.00 82.85  ? 122 SER B C   1 
ATOM   2756 O O   . SER B 2 122 ? 124.664 130.063 100.791 1.00 86.58  ? 122 SER B O   1 
ATOM   2757 C CB  . SER B 2 122 ? 121.962 129.448 101.911 1.00 80.20  ? 122 SER B CB  1 
ATOM   2758 O OG  . SER B 2 122 ? 120.869 128.630 102.285 1.00 86.59  ? 122 SER B OG  1 
ATOM   2759 N N   . ILE B 2 123 ? 123.445 130.631 98.981  1.00 79.22  ? 123 ILE B N   1 
ATOM   2760 C CA  . ILE B 2 123 ? 124.372 131.635 98.480  1.00 72.78  ? 123 ILE B CA  1 
ATOM   2761 C C   . ILE B 2 123 ? 123.839 132.997 98.889  1.00 82.71  ? 123 ILE B C   1 
ATOM   2762 O O   . ILE B 2 123 ? 122.742 133.391 98.470  1.00 87.33  ? 123 ILE B O   1 
ATOM   2763 C CB  . ILE B 2 123 ? 124.532 131.539 96.957  1.00 73.61  ? 123 ILE B CB  1 
ATOM   2764 C CG1 . ILE B 2 123 ? 124.800 130.093 96.548  1.00 79.45  ? 123 ILE B CG1 1 
ATOM   2765 C CG2 . ILE B 2 123 ? 125.637 132.459 96.481  1.00 80.22  ? 123 ILE B CG2 1 
ATOM   2766 C CD1 . ILE B 2 123 ? 126.069 129.529 97.124  1.00 79.49  ? 123 ILE B CD1 1 
ATOM   2767 N N   . TYR B 2 124 ? 124.614 133.706 99.707  1.00 81.91  ? 124 TYR B N   1 
ATOM   2768 C CA  . TYR B 2 124 ? 124.254 135.015 100.229 1.00 76.22  ? 124 TYR B CA  1 
ATOM   2769 C C   . TYR B 2 124 ? 125.024 136.083 99.469  1.00 83.57  ? 124 TYR B C   1 
ATOM   2770 O O   . TYR B 2 124 ? 126.241 135.965 99.290  1.00 87.29  ? 124 TYR B O   1 
ATOM   2771 C CB  . TYR B 2 124 ? 124.576 135.113 101.719 1.00 73.15  ? 124 TYR B CB  1 
ATOM   2772 C CG  . TYR B 2 124 ? 123.806 134.160 102.597 1.00 76.00  ? 124 TYR B CG  1 
ATOM   2773 C CD1 . TYR B 2 124 ? 122.497 134.423 102.960 1.00 80.59  ? 124 TYR B CD1 1 
ATOM   2774 C CD2 . TYR B 2 124 ? 124.394 132.998 103.069 1.00 80.24  ? 124 TYR B CD2 1 
ATOM   2775 C CE1 . TYR B 2 124 ? 121.795 133.556 103.767 1.00 79.67  ? 124 TYR B CE1 1 
ATOM   2776 C CE2 . TYR B 2 124 ? 123.699 132.125 103.874 1.00 84.46  ? 124 TYR B CE2 1 
ATOM   2777 C CZ  . TYR B 2 124 ? 122.399 132.408 104.219 1.00 83.73  ? 124 TYR B CZ  1 
ATOM   2778 O OH  . TYR B 2 124 ? 121.696 131.543 105.022 1.00 87.73  ? 124 TYR B OH  1 
ATOM   2779 N N   . ASN B 2 125 ? 124.316 137.126 99.041  1.00 84.61  ? 125 ASN B N   1 
ATOM   2780 C CA  . ASN B 2 125 ? 124.897 138.209 98.257  1.00 76.90  ? 125 ASN B CA  1 
ATOM   2781 C C   . ASN B 2 125 ? 125.289 139.345 99.195  1.00 81.23  ? 125 ASN B C   1 
ATOM   2782 O O   . ASN B 2 125 ? 124.423 140.017 99.763  1.00 90.68  ? 125 ASN B O   1 
ATOM   2783 C CB  . ASN B 2 125 ? 123.908 138.685 97.198  1.00 72.73  ? 125 ASN B CB  1 
ATOM   2784 C CG  . ASN B 2 125 ? 124.474 139.779 96.326  1.00 84.22  ? 125 ASN B CG  1 
ATOM   2785 O OD1 . ASN B 2 125 ? 125.683 139.859 96.118  1.00 90.06  ? 125 ASN B OD1 1 
ATOM   2786 N ND2 . ASN B 2 125 ? 123.600 140.621 95.794  1.00 86.53  ? 125 ASN B ND2 1 
ATOM   2787 N N   . LEU B 2 126 ? 126.595 139.559 99.357  1.00 69.98  ? 126 LEU B N   1 
ATOM   2788 C CA  . LEU B 2 126 ? 127.064 140.602 100.262 1.00 72.97  ? 126 LEU B CA  1 
ATOM   2789 C C   . LEU B 2 126 ? 126.831 141.992 99.686  1.00 82.50  ? 126 LEU B C   1 
ATOM   2790 O O   . LEU B 2 126 ? 126.363 142.893 100.392 1.00 81.60  ? 126 LEU B O   1 
ATOM   2791 C CB  . LEU B 2 126 ? 128.544 140.401 100.575 1.00 73.08  ? 126 LEU B CB  1 
ATOM   2792 C CG  . LEU B 2 126 ? 128.982 138.987 100.941 1.00 72.73  ? 126 LEU B CG  1 
ATOM   2793 C CD1 . LEU B 2 126 ? 130.460 138.965 101.265 1.00 77.84  ? 126 LEU B CD1 1 
ATOM   2794 C CD2 . LEU B 2 126 ? 128.176 138.472 102.110 1.00 75.62  ? 126 LEU B CD2 1 
ATOM   2795 N N   . LYS B 2 127 ? 127.148 142.188 98.409  1.00 85.79  ? 127 LYS B N   1 
ATOM   2796 C CA  . LYS B 2 127 ? 127.076 143.506 97.782  1.00 79.00  ? 127 LYS B CA  1 
ATOM   2797 C C   . LYS B 2 127 ? 125.653 143.734 97.294  1.00 78.38  ? 127 LYS B C   1 
ATOM   2798 O O   . LYS B 2 127 ? 125.234 143.174 96.279  1.00 88.29  ? 127 LYS B O   1 
ATOM   2799 C CB  . LYS B 2 127 ? 128.079 143.614 96.641  1.00 81.87  ? 127 LYS B CB  1 
ATOM   2800 C CG  . LYS B 2 127 ? 129.525 143.366 97.043  1.00 84.06  ? 127 LYS B CG  1 
ATOM   2801 C CD  . LYS B 2 127 ? 129.851 143.973 98.394  1.00 81.67  ? 127 LYS B CD  1 
ATOM   2802 C CE  . LYS B 2 127 ? 131.302 143.736 98.758  1.00 81.85  ? 127 LYS B CE  1 
ATOM   2803 N NZ  . LYS B 2 127 ? 132.137 143.520 97.548  1.00 84.00  ? 127 LYS B NZ  1 
ATOM   2804 N N   . THR B 2 128 ? 124.907 144.562 98.018  1.00 74.41  ? 128 THR B N   1 
ATOM   2805 C CA  . THR B 2 128 ? 123.548 144.916 97.642  1.00 79.52  ? 128 THR B CA  1 
ATOM   2806 C C   . THR B 2 128 ? 123.360 146.414 97.816  1.00 82.54  ? 128 THR B C   1 
ATOM   2807 O O   . THR B 2 128 ? 124.077 147.064 98.581  1.00 87.37  ? 128 THR B O   1 
ATOM   2808 C CB  . THR B 2 128 ? 122.506 144.162 98.477  1.00 82.28  ? 128 THR B CB  1 
ATOM   2809 O OG1 . THR B 2 128 ? 122.905 144.162 99.853  1.00 85.16  ? 128 THR B OG1 1 
ATOM   2810 C CG2 . THR B 2 128 ? 122.366 142.732 97.995  1.00 82.75  ? 128 THR B CG2 1 
ATOM   2811 N N   . ARG B 2 129 ? 122.387 146.962 97.087  1.00 86.98  ? 129 ARG B N   1 
ATOM   2812 C CA  . ARG B 2 129 ? 122.026 148.360 97.288  1.00 85.13  ? 129 ARG B CA  1 
ATOM   2813 C C   . ARG B 2 129 ? 121.531 148.588 98.709  1.00 85.47  ? 129 ARG B C   1 
ATOM   2814 O O   . ARG B 2 129 ? 121.885 149.584 99.349  1.00 91.39  ? 129 ARG B O   1 
ATOM   2815 C CB  . ARG B 2 129 ? 120.967 148.784 96.272  1.00 85.36  ? 129 ARG B CB  1 
ATOM   2816 C CG  . ARG B 2 129 ? 121.448 148.760 94.834  1.00 87.13  ? 129 ARG B CG  1 
ATOM   2817 C CD  . ARG B 2 129 ? 122.762 149.509 94.674  1.00 87.92  ? 129 ARG B CD  1 
ATOM   2818 N NE  . ARG B 2 129 ? 122.646 150.917 95.032  1.00 90.91  ? 129 ARG B NE  1 
ATOM   2819 C CZ  . ARG B 2 129 ? 122.059 151.838 94.280  1.00 91.99  ? 129 ARG B CZ  1 
ATOM   2820 N NH1 . ARG B 2 129 ? 121.516 151.535 93.113  1.00 91.57  ? 129 ARG B NH1 1 
ATOM   2821 N NH2 . ARG B 2 129 ? 122.019 153.096 94.708  1.00 88.80  ? 129 ARG B NH2 1 
ATOM   2822 N N   . GLU B 2 130 ? 120.713 147.673 99.217  1.00 85.74  ? 130 GLU B N   1 
ATOM   2823 C CA  . GLU B 2 130 ? 120.335 147.679 100.621 1.00 85.01  ? 130 GLU B CA  1 
ATOM   2824 C C   . GLU B 2 130 ? 121.434 147.007 101.431 1.00 86.40  ? 130 GLU B C   1 
ATOM   2825 O O   . GLU B 2 130 ? 121.861 145.896 101.108 1.00 94.14  ? 130 GLU B O   1 
ATOM   2826 C CB  . GLU B 2 130 ? 119.008 146.953 100.813 1.00 87.85  ? 130 GLU B CB  1 
ATOM   2827 C CG  . GLU B 2 130 ? 118.043 147.139 99.660  1.00 95.49  ? 130 GLU B CG  1 
ATOM   2828 C CD  . GLU B 2 130 ? 116.728 146.422 99.878  1.00 101.21 ? 130 GLU B CD  1 
ATOM   2829 O OE1 . GLU B 2 130 ? 116.033 146.737 100.868 1.00 104.47 ? 130 GLU B OE1 1 
ATOM   2830 O OE2 . GLU B 2 130 ? 116.386 145.543 99.060  1.00 95.15  ? 130 GLU B OE2 1 
ATOM   2831 N N   . GLY B 2 131 ? 121.890 147.674 102.485 1.00 73.92  ? 131 GLY B N   1 
ATOM   2832 C CA  . GLY B 2 131 ? 123.053 147.198 103.209 1.00 74.04  ? 131 GLY B CA  1 
ATOM   2833 C C   . GLY B 2 131 ? 122.796 146.033 104.141 1.00 78.75  ? 131 GLY B C   1 
ATOM   2834 O O   . GLY B 2 131 ? 123.273 146.026 105.279 1.00 84.20  ? 131 GLY B O   1 
ATOM   2835 N N   . ASN B 2 132 ? 122.049 145.039 103.672 1.00 84.25  ? 132 ASN B N   1 
ATOM   2836 C CA  . ASN B 2 132 ? 121.829 143.809 104.415 1.00 83.27  ? 132 ASN B CA  1 
ATOM   2837 C C   . ASN B 2 132 ? 122.080 142.627 103.495 1.00 89.00  ? 132 ASN B C   1 
ATOM   2838 O O   . ASN B 2 132 ? 121.621 142.613 102.349 1.00 91.01  ? 132 ASN B O   1 
ATOM   2839 C CB  . ASN B 2 132 ? 120.411 143.734 104.986 1.00 80.36  ? 132 ASN B CB  1 
ATOM   2840 C CG  . ASN B 2 132 ? 119.355 144.101 103.968 1.00 86.34  ? 132 ASN B CG  1 
ATOM   2841 O OD1 . ASN B 2 132 ? 119.310 145.231 103.486 1.00 90.80  ? 132 ASN B OD1 1 
ATOM   2842 N ND2 . ASN B 2 132 ? 118.498 143.146 103.634 1.00 85.42  ? 132 ASN B ND2 1 
ATOM   2843 N N   . VAL B 2 133 ? 122.811 141.637 104.000 1.00 79.46  ? 133 VAL B N   1 
ATOM   2844 C CA  . VAL B 2 133 ? 123.104 140.447 103.214 1.00 73.63  ? 133 VAL B CA  1 
ATOM   2845 C C   . VAL B 2 133 ? 121.829 139.627 103.076 1.00 75.29  ? 133 VAL B C   1 
ATOM   2846 O O   . VAL B 2 133 ? 121.189 139.275 104.073 1.00 79.80  ? 133 VAL B O   1 
ATOM   2847 C CB  . VAL B 2 133 ? 124.226 139.629 103.859 1.00 76.67  ? 133 VAL B CB  1 
ATOM   2848 C CG1 . VAL B 2 133 ? 124.433 138.339 103.099 1.00 78.44  ? 133 VAL B CG1 1 
ATOM   2849 C CG2 . VAL B 2 133 ? 125.504 140.438 103.896 1.00 77.58  ? 133 VAL B CG2 1 
ATOM   2850 N N   . ARG B 2 134 ? 121.453 139.322 101.839 1.00 73.80  ? 134 ARG B N   1 
ATOM   2851 C CA  . ARG B 2 134 ? 120.238 138.578 101.551 1.00 75.77  ? 134 ARG B CA  1 
ATOM   2852 C C   . ARG B 2 134 ? 120.582 137.230 100.937 1.00 83.02  ? 134 ARG B C   1 
ATOM   2853 O O   . ARG B 2 134 ? 121.689 137.011 100.440 1.00 87.02  ? 134 ARG B O   1 
ATOM   2854 C CB  . ARG B 2 134 ? 119.315 139.353 100.606 1.00 79.59  ? 134 ARG B CB  1 
ATOM   2855 C CG  . ARG B 2 134 ? 118.695 140.594 101.214 1.00 84.80  ? 134 ARG B CG  1 
ATOM   2856 C CD  . ARG B 2 134 ? 117.832 141.321 100.199 1.00 87.22  ? 134 ARG B CD  1 
ATOM   2857 N NE  . ARG B 2 134 ? 118.576 141.643 98.987  1.00 89.38  ? 134 ARG B NE  1 
ATOM   2858 C CZ  . ARG B 2 134 ? 118.315 141.133 97.792  1.00 88.45  ? 134 ARG B CZ  1 
ATOM   2859 N NH1 . ARG B 2 134 ? 117.328 140.271 97.609  1.00 83.54  ? 134 ARG B NH1 1 
ATOM   2860 N NH2 . ARG B 2 134 ? 119.063 141.495 96.754  1.00 87.42  ? 134 ARG B NH2 1 
ATOM   2861 N N   . VAL B 2 135 ? 119.606 136.325 100.975 1.00 84.01  ? 135 VAL B N   1 
ATOM   2862 C CA  . VAL B 2 135 ? 119.760 134.984 100.417 1.00 73.16  ? 135 VAL B CA  1 
ATOM   2863 C C   . VAL B 2 135 ? 119.615 135.110 98.904  1.00 77.77  ? 135 VAL B C   1 
ATOM   2864 O O   . VAL B 2 135 ? 118.503 135.151 98.377  1.00 81.19  ? 135 VAL B O   1 
ATOM   2865 C CB  . VAL B 2 135 ? 118.741 134.003 100.998 1.00 73.72  ? 135 VAL B CB  1 
ATOM   2866 C CG1 . VAL B 2 135 ? 119.106 132.581 100.619 1.00 75.85  ? 135 VAL B CG1 1 
ATOM   2867 C CG2 . VAL B 2 135 ? 118.648 134.162 102.502 1.00 78.17  ? 135 VAL B CG2 1 
ATOM   2868 N N   . SER B 2 136 ? 120.744 135.180 98.199  1.00 82.94  ? 136 SER B N   1 
ATOM   2869 C CA  . SER B 2 136 ? 120.696 135.282 96.745  1.00 84.73  ? 136 SER B CA  1 
ATOM   2870 C C   . SER B 2 136 ? 120.108 134.027 96.119  1.00 88.82  ? 136 SER B C   1 
ATOM   2871 O O   . SER B 2 136 ? 119.312 134.113 95.178  1.00 88.83  ? 136 SER B O   1 
ATOM   2872 C CB  . SER B 2 136 ? 122.093 135.549 96.190  1.00 87.03  ? 136 SER B CB  1 
ATOM   2873 O OG  . SER B 2 136 ? 122.132 135.330 94.792  1.00 93.86  ? 136 SER B OG  1 
ATOM   2874 N N   . ARG B 2 137 ? 120.483 132.853 96.623  1.00 90.47  ? 137 ARG B N   1 
ATOM   2875 C CA  . ARG B 2 137 ? 120.032 131.612 96.009  1.00 84.55  ? 137 ARG B CA  1 
ATOM   2876 C C   . ARG B 2 137 ? 119.988 130.502 97.049  1.00 87.02  ? 137 ARG B C   1 
ATOM   2877 O O   . ARG B 2 137 ? 120.761 130.503 98.008  1.00 91.19  ? 137 ARG B O   1 
ATOM   2878 C CB  . ARG B 2 137 ? 120.943 131.218 94.840  1.00 83.68  ? 137 ARG B CB  1 
ATOM   2879 C CG  . ARG B 2 137 ? 120.466 130.023 94.045  1.00 88.25  ? 137 ARG B CG  1 
ATOM   2880 C CD  . ARG B 2 137 ? 119.228 130.365 93.243  1.00 87.64  ? 137 ARG B CD  1 
ATOM   2881 N NE  . ARG B 2 137 ? 119.417 131.563 92.438  1.00 89.24  ? 137 ARG B NE  1 
ATOM   2882 C CZ  . ARG B 2 137 ? 118.492 132.080 91.641  1.00 88.88  ? 137 ARG B CZ  1 
ATOM   2883 N NH1 . ARG B 2 137 ? 117.297 131.526 91.520  1.00 86.57  ? 137 ARG B NH1 1 
ATOM   2884 N NH2 . ARG B 2 137 ? 118.773 133.181 90.950  1.00 88.27  ? 137 ARG B NH2 1 
ATOM   2885 N N   . GLU B 2 138 ? 119.071 129.557 96.854  1.00 89.57  ? 138 GLU B N   1 
ATOM   2886 C CA  . GLU B 2 138 ? 118.964 128.362 97.690  1.00 87.53  ? 138 GLU B CA  1 
ATOM   2887 C C   . GLU B 2 138 ? 119.063 127.145 96.776  1.00 93.47  ? 138 GLU B C   1 
ATOM   2888 O O   . GLU B 2 138 ? 118.048 126.622 96.311  1.00 98.73  ? 138 GLU B O   1 
ATOM   2889 C CB  . GLU B 2 138 ? 117.668 128.353 98.486  1.00 86.28  ? 138 GLU B CB  1 
ATOM   2890 C CG  . GLU B 2 138 ? 117.710 129.193 99.744  1.00 91.57  ? 138 GLU B CG  1 
ATOM   2891 C CD  . GLU B 2 138 ? 116.590 128.852 100.703 1.00 97.72  ? 138 GLU B CD  1 
ATOM   2892 O OE1 . GLU B 2 138 ? 115.793 127.945 100.386 1.00 95.36  ? 138 GLU B OE1 1 
ATOM   2893 O OE2 . GLU B 2 138 ? 116.507 129.489 101.774 1.00 96.92  ? 138 GLU B OE2 1 
ATOM   2894 N N   . LEU B 2 139 ? 120.289 126.695 96.521  1.00 80.91  ? 139 LEU B N   1 
ATOM   2895 C CA  . LEU B 2 139 ? 120.506 125.541 95.662  1.00 75.57  ? 139 LEU B CA  1 
ATOM   2896 C C   . LEU B 2 139 ? 120.107 124.269 96.397  1.00 79.00  ? 139 LEU B C   1 
ATOM   2897 O O   . LEU B 2 139 ? 120.637 123.972 97.473  1.00 78.18  ? 139 LEU B O   1 
ATOM   2898 C CB  . LEU B 2 139 ? 121.966 125.480 95.233  1.00 72.48  ? 139 LEU B CB  1 
ATOM   2899 C CG  . LEU B 2 139 ? 122.520 126.772 94.640  1.00 77.39  ? 139 LEU B CG  1 
ATOM   2900 C CD1 . LEU B 2 139 ? 124.019 126.834 94.827  1.00 80.22  ? 139 LEU B CD1 1 
ATOM   2901 C CD2 . LEU B 2 139 ? 122.159 126.878 93.173  1.00 80.71  ? 139 LEU B CD2 1 
ATOM   2902 N N   . ALA B 2 140 ? 119.177 123.518 95.813  1.00 85.34  ? 140 ALA B N   1 
ATOM   2903 C CA  . ALA B 2 140 ? 118.658 122.304 96.422  1.00 81.57  ? 140 ALA B CA  1 
ATOM   2904 C C   . ALA B 2 140 ? 118.611 121.203 95.375  1.00 81.70  ? 140 ALA B C   1 
ATOM   2905 O O   . ALA B 2 140 ? 118.533 121.463 94.173  1.00 85.63  ? 140 ALA B O   1 
ATOM   2906 C CB  . ALA B 2 140 ? 117.266 122.522 97.026  1.00 81.72  ? 140 ALA B CB  1 
ATOM   2907 N N   . GLY B 2 141 ? 118.636 119.964 95.851  1.00 75.49  ? 141 GLY B N   1 
ATOM   2908 C CA  . GLY B 2 141 ? 118.732 118.814 94.976  1.00 75.67  ? 141 GLY B CA  1 
ATOM   2909 C C   . GLY B 2 141 ? 119.574 117.715 95.585  1.00 76.73  ? 141 GLY B C   1 
ATOM   2910 O O   . GLY B 2 141 ? 119.419 116.539 95.245  1.00 82.54  ? 141 GLY B O   1 
ATOM   2911 N N   . HIS B 2 142 ? 120.475 118.089 96.486  1.00 74.90  ? 142 HIS B N   1 
ATOM   2912 C CA  . HIS B 2 142 ? 121.179 117.102 97.289  1.00 78.41  ? 142 HIS B CA  1 
ATOM   2913 C C   . HIS B 2 142 ? 120.236 116.518 98.332  1.00 84.74  ? 142 HIS B C   1 
ATOM   2914 O O   . HIS B 2 142 ? 119.435 117.237 98.936  1.00 89.30  ? 142 HIS B O   1 
ATOM   2915 C CB  . HIS B 2 142 ? 122.384 117.739 97.975  1.00 76.16  ? 142 HIS B CB  1 
ATOM   2916 C CG  . HIS B 2 142 ? 123.640 117.686 97.167  1.00 74.09  ? 142 HIS B CG  1 
ATOM   2917 N ND1 . HIS B 2 142 ? 124.002 116.583 96.426  1.00 80.10  ? 142 HIS B ND1 1 
ATOM   2918 C CD2 . HIS B 2 142 ? 124.623 118.598 96.989  1.00 75.23  ? 142 HIS B CD2 1 
ATOM   2919 C CE1 . HIS B 2 142 ? 125.153 116.819 95.823  1.00 80.08  ? 142 HIS B CE1 1 
ATOM   2920 N NE2 . HIS B 2 142 ? 125.551 118.035 96.148  1.00 78.31  ? 142 HIS B NE2 1 
ATOM   2921 N N   . THR B 2 143 ? 120.323 115.206 98.539  1.00 82.47  ? 143 THR B N   1 
ATOM   2922 C CA  . THR B 2 143 ? 119.536 114.540 99.569  1.00 82.45  ? 143 THR B CA  1 
ATOM   2923 C C   . THR B 2 143 ? 120.387 114.124 100.761 1.00 82.21  ? 143 THR B C   1 
ATOM   2924 O O   . THR B 2 143 ? 119.903 113.396 101.634 1.00 87.46  ? 143 THR B O   1 
ATOM   2925 C CB  . THR B 2 143 ? 118.806 113.328 98.987  1.00 86.88  ? 143 THR B CB  1 
ATOM   2926 O OG1 . THR B 2 143 ? 119.713 112.229 98.863  1.00 90.59  ? 143 THR B OG1 1 
ATOM   2927 C CG2 . THR B 2 143 ? 118.242 113.659 97.617  1.00 82.44  ? 143 THR B CG2 1 
ATOM   2928 N N   . GLY B 2 144 ? 121.643 114.565 100.815 1.00 78.40  ? 144 GLY B N   1 
ATOM   2929 C CA  . GLY B 2 144 ? 122.492 114.306 101.953 1.00 81.20  ? 144 GLY B CA  1 
ATOM   2930 C C   . GLY B 2 144 ? 123.130 115.591 102.442 1.00 79.76  ? 144 GLY B C   1 
ATOM   2931 O O   . GLY B 2 144 ? 123.112 116.617 101.763 1.00 85.57  ? 144 GLY B O   1 
ATOM   2932 N N   . TYR B 2 145 ? 123.684 115.522 103.649 1.00 80.52  ? 145 TYR B N   1 
ATOM   2933 C CA  . TYR B 2 145 ? 124.269 116.704 104.266 1.00 78.65  ? 145 TYR B CA  1 
ATOM   2934 C C   . TYR B 2 145 ? 125.417 117.249 103.427 1.00 85.00  ? 145 TYR B C   1 
ATOM   2935 O O   . TYR B 2 145 ? 126.247 116.496 102.915 1.00 94.50  ? 145 TYR B O   1 
ATOM   2936 C CB  . TYR B 2 145 ? 124.753 116.385 105.683 1.00 84.89  ? 145 TYR B CB  1 
ATOM   2937 C CG  . TYR B 2 145 ? 125.864 115.357 105.772 1.00 84.40  ? 145 TYR B CG  1 
ATOM   2938 C CD1 . TYR B 2 145 ? 127.193 115.733 105.703 1.00 78.94  ? 145 TYR B CD1 1 
ATOM   2939 C CD2 . TYR B 2 145 ? 125.580 114.018 105.967 1.00 88.41  ? 145 TYR B CD2 1 
ATOM   2940 C CE1 . TYR B 2 145 ? 128.206 114.808 105.798 1.00 82.47  ? 145 TYR B CE1 1 
ATOM   2941 C CE2 . TYR B 2 145 ? 126.590 113.083 106.064 1.00 90.20  ? 145 TYR B CE2 1 
ATOM   2942 C CZ  . TYR B 2 145 ? 127.900 113.485 105.978 1.00 91.24  ? 145 TYR B CZ  1 
ATOM   2943 O OH  . TYR B 2 145 ? 128.909 112.556 106.074 1.00 98.42  ? 145 TYR B OH  1 
ATOM   2944 N N   . LEU B 2 146 ? 125.459 118.572 103.291 1.00 78.76  ? 146 LEU B N   1 
ATOM   2945 C CA  . LEU B 2 146 ? 126.516 119.231 102.535 1.00 72.40  ? 146 LEU B CA  1 
ATOM   2946 C C   . LEU B 2 146 ? 127.744 119.388 103.419 1.00 78.19  ? 146 LEU B C   1 
ATOM   2947 O O   . LEU B 2 146 ? 127.671 120.001 104.488 1.00 87.64  ? 146 LEU B O   1 
ATOM   2948 C CB  . LEU B 2 146 ? 126.041 120.589 102.031 1.00 74.27  ? 146 LEU B CB  1 
ATOM   2949 C CG  . LEU B 2 146 ? 125.701 120.660 100.547 1.00 85.56  ? 146 LEU B CG  1 
ATOM   2950 C CD1 . LEU B 2 146 ? 124.347 120.026 100.283 1.00 87.03  ? 146 LEU B CD1 1 
ATOM   2951 C CD2 . LEU B 2 146 ? 125.720 122.095 100.075 1.00 84.34  ? 146 LEU B CD2 1 
ATOM   2952 N N   . SER B 2 147 ? 128.872 118.840 102.974 1.00 77.69  ? 147 SER B N   1 
ATOM   2953 C CA  . SER B 2 147 ? 130.091 118.862 103.768 1.00 83.73  ? 147 SER B CA  1 
ATOM   2954 C C   . SER B 2 147 ? 131.065 119.953 103.355 1.00 89.67  ? 147 SER B C   1 
ATOM   2955 O O   . SER B 2 147 ? 131.820 120.441 104.201 1.00 93.57  ? 147 SER B O   1 
ATOM   2956 C CB  . SER B 2 147 ? 130.800 117.508 103.685 1.00 86.98  ? 147 SER B CB  1 
ATOM   2957 O OG  . SER B 2 147 ? 129.865 116.445 103.680 1.00 90.42  ? 147 SER B OG  1 
ATOM   2958 N N   . CYS B 2 148 ? 131.076 120.344 102.084 1.00 77.27  ? 148 CYS B N   1 
ATOM   2959 C CA  . CYS B 2 148 ? 132.012 121.360 101.630 1.00 74.89  ? 148 CYS B CA  1 
ATOM   2960 C C   . CYS B 2 148 ? 131.455 122.047 100.394 1.00 82.56  ? 148 CYS B C   1 
ATOM   2961 O O   . CYS B 2 148 ? 130.853 121.399 99.535  1.00 84.82  ? 148 CYS B O   1 
ATOM   2962 C CB  . CYS B 2 148 ? 133.386 120.758 101.326 1.00 76.49  ? 148 CYS B CB  1 
ATOM   2963 S SG  . CYS B 2 148 ? 134.666 121.986 101.019 1.00 97.10  ? 148 CYS B SG  1 
ATOM   2964 N N   . CYS B 2 149 ? 131.663 123.358 100.318 1.00 80.43  ? 149 CYS B N   1 
ATOM   2965 C CA  . CYS B 2 149 ? 131.269 124.166 99.175  1.00 70.52  ? 149 CYS B CA  1 
ATOM   2966 C C   . CYS B 2 149 ? 132.450 125.023 98.756  1.00 76.24  ? 149 CYS B C   1 
ATOM   2967 O O   . CYS B 2 149 ? 133.184 125.535 99.606  1.00 87.05  ? 149 CYS B O   1 
ATOM   2968 C CB  . CYS B 2 149 ? 130.073 125.056 99.506  1.00 74.79  ? 149 CYS B CB  1 
ATOM   2969 S SG  . CYS B 2 149 ? 128.650 124.173 100.160 1.00 93.93  ? 149 CYS B SG  1 
ATOM   2970 N N   . ARG B 2 150 ? 132.637 125.177 97.448  1.00 68.08  ? 150 ARG B N   1 
ATOM   2971 C CA  . ARG B 2 150 ? 133.719 125.996 96.915  1.00 72.88  ? 150 ARG B CA  1 
ATOM   2972 C C   . ARG B 2 150 ? 133.221 126.724 95.677  1.00 79.04  ? 150 ARG B C   1 
ATOM   2973 O O   . ARG B 2 150 ? 132.815 126.084 94.703  1.00 84.01  ? 150 ARG B O   1 
ATOM   2974 C CB  . ARG B 2 150 ? 134.947 125.148 96.576  1.00 69.65  ? 150 ARG B CB  1 
ATOM   2975 C CG  . ARG B 2 150 ? 135.742 124.678 97.778  1.00 67.67  ? 150 ARG B CG  1 
ATOM   2976 C CD  . ARG B 2 150 ? 136.214 125.843 98.623  1.00 70.71  ? 150 ARG B CD  1 
ATOM   2977 N NE  . ARG B 2 150 ? 136.875 125.394 99.840  1.00 67.01  ? 150 ARG B NE  1 
ATOM   2978 C CZ  . ARG B 2 150 ? 136.338 125.457 101.050 1.00 68.42  ? 150 ARG B CZ  1 
ATOM   2979 N NH1 . ARG B 2 150 ? 135.121 125.935 101.241 1.00 65.68  ? 150 ARG B NH1 1 
ATOM   2980 N NH2 . ARG B 2 150 ? 137.039 125.026 102.094 1.00 77.25  ? 150 ARG B NH2 1 
ATOM   2981 N N   . PHE B 2 151 ? 133.255 128.052 95.717  1.00 71.18  ? 151 PHE B N   1 
ATOM   2982 C CA  . PHE B 2 151 ? 132.909 128.845 94.548  1.00 67.42  ? 151 PHE B CA  1 
ATOM   2983 C C   . PHE B 2 151 ? 133.971 128.690 93.470  1.00 68.92  ? 151 PHE B C   1 
ATOM   2984 O O   . PHE B 2 151 ? 135.126 128.359 93.747  1.00 74.47  ? 151 PHE B O   1 
ATOM   2985 C CB  . PHE B 2 151 ? 132.777 130.319 94.919  1.00 73.20  ? 151 PHE B CB  1 
ATOM   2986 C CG  . PHE B 2 151 ? 131.436 130.694 95.461  1.00 71.52  ? 151 PHE B CG  1 
ATOM   2987 C CD1 . PHE B 2 151 ? 130.387 130.972 94.609  1.00 76.16  ? 151 PHE B CD1 1 
ATOM   2988 C CD2 . PHE B 2 151 ? 131.229 130.789 96.820  1.00 72.07  ? 151 PHE B CD2 1 
ATOM   2989 C CE1 . PHE B 2 151 ? 129.155 131.324 95.105  1.00 80.03  ? 151 PHE B CE1 1 
ATOM   2990 C CE2 . PHE B 2 151 ? 130.001 131.143 97.319  1.00 74.08  ? 151 PHE B CE2 1 
ATOM   2991 C CZ  . PHE B 2 151 ? 128.964 131.410 96.462  1.00 78.44  ? 151 PHE B CZ  1 
ATOM   2992 N N   . LEU B 2 152 ? 133.570 128.927 92.223  1.00 72.73  ? 152 LEU B N   1 
ATOM   2993 C CA  . LEU B 2 152 ? 134.503 128.919 91.106  1.00 77.95  ? 152 LEU B CA  1 
ATOM   2994 C C   . LEU B 2 152 ? 134.610 130.281 90.432  1.00 81.57  ? 152 LEU B C   1 
ATOM   2995 O O   . LEU B 2 152 ? 135.683 130.888 90.435  1.00 84.79  ? 152 LEU B O   1 
ATOM   2996 C CB  . LEU B 2 152 ? 134.086 127.854 90.085  1.00 77.34  ? 152 LEU B CB  1 
ATOM   2997 C CG  . LEU B 2 152 ? 134.355 126.398 90.455  1.00 79.42  ? 152 LEU B CG  1 
ATOM   2998 C CD1 . LEU B 2 152 ? 133.133 125.788 91.110  1.00 82.42  ? 152 LEU B CD1 1 
ATOM   2999 C CD2 . LEU B 2 152 ? 134.737 125.613 89.222  1.00 78.52  ? 152 LEU B CD2 1 
ATOM   3000 N N   . ASP B 2 153 ? 133.521 130.783 89.853  1.00 90.37  ? 153 ASP B N   1 
ATOM   3001 C CA  . ASP B 2 153 ? 133.558 132.035 89.105  1.00 94.01  ? 153 ASP B CA  1 
ATOM   3002 C C   . ASP B 2 153 ? 132.326 132.886 89.382  1.00 95.21  ? 153 ASP B C   1 
ATOM   3003 O O   . ASP B 2 153 ? 131.777 133.524 88.477  1.00 102.92 ? 153 ASP B O   1 
ATOM   3004 C CB  . ASP B 2 153 ? 133.729 131.769 87.606  1.00 102.22 ? 153 ASP B CB  1 
ATOM   3005 C CG  . ASP B 2 153 ? 132.552 131.017 86.989  1.00 104.26 ? 153 ASP B CG  1 
ATOM   3006 O OD1 . ASP B 2 153 ? 131.495 130.871 87.637  1.00 104.94 ? 153 ASP B OD1 1 
ATOM   3007 O OD2 . ASP B 2 153 ? 132.692 130.565 85.833  1.00 98.23  ? 153 ASP B OD2 1 
ATOM   3008 N N   . ASP B 2 154 ? 131.864 132.898 90.632  1.00 82.44  ? 154 ASP B N   1 
ATOM   3009 C CA  . ASP B 2 154 ? 130.713 133.668 91.097  1.00 84.71  ? 154 ASP B CA  1 
ATOM   3010 C C   . ASP B 2 154 ? 129.399 133.178 90.510  1.00 86.63  ? 154 ASP B C   1 
ATOM   3011 O O   . ASP B 2 154 ? 128.342 133.700 90.879  1.00 92.01  ? 154 ASP B O   1 
ATOM   3012 C CB  . ASP B 2 154 ? 130.845 135.169 90.802  1.00 83.81  ? 154 ASP B CB  1 
ATOM   3013 C CG  . ASP B 2 154 ? 131.059 135.992 92.050  1.00 88.01  ? 154 ASP B CG  1 
ATOM   3014 O OD1 . ASP B 2 154 ? 131.154 135.400 93.143  1.00 89.79  ? 154 ASP B OD1 1 
ATOM   3015 O OD2 . ASP B 2 154 ? 131.131 137.233 91.938  1.00 90.03  ? 154 ASP B OD2 1 
ATOM   3016 N N   . ASN B 2 155 ? 129.422 132.197 89.611  1.00 82.82  ? 155 ASN B N   1 
ATOM   3017 C CA  . ASN B 2 155 ? 128.208 131.654 89.027  1.00 80.14  ? 155 ASN B CA  1 
ATOM   3018 C C   . ASN B 2 155 ? 128.166 130.136 89.032  1.00 87.28  ? 155 ASN B C   1 
ATOM   3019 O O   . ASN B 2 155 ? 127.092 129.568 88.812  1.00 93.87  ? 155 ASN B O   1 
ATOM   3020 C CB  . ASN B 2 155 ? 128.032 132.153 87.586  1.00 81.47  ? 155 ASN B CB  1 
ATOM   3021 C CG  . ASN B 2 155 ? 126.599 132.072 87.116  1.00 85.87  ? 155 ASN B CG  1 
ATOM   3022 O OD1 . ASN B 2 155 ? 126.311 131.516 86.057  1.00 86.58  ? 155 ASN B OD1 1 
ATOM   3023 N ND2 . ASN B 2 155 ? 125.687 132.623 87.905  1.00 86.27  ? 155 ASN B ND2 1 
ATOM   3024 N N   . GLN B 2 156 ? 129.289 129.466 89.269  1.00 83.40  ? 156 GLN B N   1 
ATOM   3025 C CA  . GLN B 2 156 ? 129.340 128.018 89.394  1.00 76.32  ? 156 GLN B CA  1 
ATOM   3026 C C   . GLN B 2 156 ? 129.941 127.671 90.745  1.00 81.87  ? 156 GLN B C   1 
ATOM   3027 O O   . GLN B 2 156 ? 130.977 128.223 91.128  1.00 89.65  ? 156 GLN B O   1 
ATOM   3028 C CB  . GLN B 2 156 ? 130.168 127.390 88.272  1.00 75.47  ? 156 GLN B CB  1 
ATOM   3029 C CG  . GLN B 2 156 ? 129.980 128.036 86.920  1.00 77.17  ? 156 GLN B CG  1 
ATOM   3030 C CD  . GLN B 2 156 ? 130.926 127.478 85.883  1.00 85.77  ? 156 GLN B CD  1 
ATOM   3031 O OE1 . GLN B 2 156 ? 131.579 126.461 86.109  1.00 88.91  ? 156 GLN B OE1 1 
ATOM   3032 N NE2 . GLN B 2 156 ? 131.009 128.142 84.737  1.00 86.61  ? 156 GLN B NE2 1 
ATOM   3033 N N   . ILE B 2 157 ? 129.289 126.766 91.465  1.00 76.69  ? 157 ILE B N   1 
ATOM   3034 C CA  . ILE B 2 157 ? 129.765 126.317 92.768  1.00 70.64  ? 157 ILE B CA  1 
ATOM   3035 C C   . ILE B 2 157 ? 129.718 124.796 92.817  1.00 77.77  ? 157 ILE B C   1 
ATOM   3036 O O   . ILE B 2 157 ? 128.758 124.179 92.349  1.00 86.55  ? 157 ILE B O   1 
ATOM   3037 C CB  . ILE B 2 157 ? 128.945 126.933 93.920  1.00 62.32  ? 157 ILE B CB  1 
ATOM   3038 C CG1 . ILE B 2 157 ? 129.544 126.552 95.271  1.00 74.60  ? 157 ILE B CG1 1 
ATOM   3039 C CG2 . ILE B 2 157 ? 127.498 126.510 93.847  1.00 68.83  ? 157 ILE B CG2 1 
ATOM   3040 C CD1 . ILE B 2 157 ? 128.753 127.059 96.446  1.00 80.88  ? 157 ILE B CD1 1 
ATOM   3041 N N   . VAL B 2 158 ? 130.758 124.187 93.375  1.00 67.38  ? 158 VAL B N   1 
ATOM   3042 C CA  . VAL B 2 158 ? 130.817 122.740 93.537  1.00 60.47  ? 158 VAL B CA  1 
ATOM   3043 C C   . VAL B 2 158 ? 130.554 122.414 94.999  1.00 69.21  ? 158 VAL B C   1 
ATOM   3044 O O   . VAL B 2 158 ? 131.218 122.948 95.896  1.00 80.16  ? 158 VAL B O   1 
ATOM   3045 C CB  . VAL B 2 158 ? 132.155 122.168 93.054  1.00 61.00  ? 158 VAL B CB  1 
ATOM   3046 C CG1 . VAL B 2 158 ? 132.240 122.263 91.553  1.00 70.26  ? 158 VAL B CG1 1 
ATOM   3047 C CG2 . VAL B 2 158 ? 133.284 122.953 93.644  1.00 70.56  ? 158 VAL B CG2 1 
ATOM   3048 N N   . THR B 2 159 ? 129.568 121.556 95.237  1.00 72.65  ? 159 THR B N   1 
ATOM   3049 C CA  . THR B 2 159 ? 129.153 121.178 96.580  1.00 75.43  ? 159 THR B CA  1 
ATOM   3050 C C   . THR B 2 159 ? 129.203 119.666 96.719  1.00 80.10  ? 159 THR B C   1 
ATOM   3051 O O   . THR B 2 159 ? 128.592 118.948 95.924  1.00 84.63  ? 159 THR B O   1 
ATOM   3052 C CB  . THR B 2 159 ? 127.741 121.680 96.886  1.00 71.45  ? 159 THR B CB  1 
ATOM   3053 O OG1 . THR B 2 159 ? 126.809 121.058 95.996  1.00 79.58  ? 159 THR B OG1 1 
ATOM   3054 C CG2 . THR B 2 159 ? 127.661 123.187 96.720  1.00 77.21  ? 159 THR B CG2 1 
ATOM   3055 N N   . SER B 2 160 ? 129.927 119.188 97.725  1.00 78.87  ? 160 SER B N   1 
ATOM   3056 C CA  . SER B 2 160 ? 129.989 117.769 98.045  1.00 75.61  ? 160 SER B CA  1 
ATOM   3057 C C   . SER B 2 160 ? 128.996 117.475 99.157  1.00 76.66  ? 160 SER B C   1 
ATOM   3058 O O   . SER B 2 160 ? 128.930 118.215 100.143 1.00 83.91  ? 160 SER B O   1 
ATOM   3059 C CB  . SER B 2 160 ? 131.398 117.370 98.477  1.00 81.58  ? 160 SER B CB  1 
ATOM   3060 O OG  . SER B 2 160 ? 131.712 117.923 99.742  1.00 86.49  ? 160 SER B OG  1 
ATOM   3061 N N   . SER B 2 161 ? 128.225 116.405 99.005  1.00 84.46  ? 161 SER B N   1 
ATOM   3062 C CA  . SER B 2 161 ? 127.157 116.110 99.946  1.00 87.91  ? 161 SER B CA  1 
ATOM   3063 C C   . SER B 2 161 ? 127.370 114.744 100.586 1.00 87.49  ? 161 SER B C   1 
ATOM   3064 O O   . SER B 2 161 ? 128.349 114.045 100.317 1.00 90.82  ? 161 SER B O   1 
ATOM   3065 C CB  . SER B 2 161 ? 125.794 116.169 99.254  1.00 91.26  ? 161 SER B CB  1 
ATOM   3066 O OG  . SER B 2 161 ? 125.625 115.075 98.371  1.00 91.23  ? 161 SER B OG  1 
ATOM   3067 N N   . GLY B 2 162 ? 126.431 114.375 101.450 1.00 87.55  ? 162 GLY B N   1 
ATOM   3068 C CA  . GLY B 2 162 ? 126.392 113.067 102.060 1.00 84.27  ? 162 GLY B CA  1 
ATOM   3069 C C   . GLY B 2 162 ? 125.767 111.994 101.206 1.00 90.56  ? 162 GLY B C   1 
ATOM   3070 O O   . GLY B 2 162 ? 125.658 110.844 101.638 1.00 94.77  ? 162 GLY B O   1 
ATOM   3071 N N   . ASP B 2 163 ? 125.345 112.346 99.997  1.00 87.97  ? 163 ASP B N   1 
ATOM   3072 C CA  . ASP B 2 163 ? 124.800 111.402 99.034  1.00 86.03  ? 163 ASP B CA  1 
ATOM   3073 C C   . ASP B 2 163 ? 125.876 110.632 98.295  1.00 86.42  ? 163 ASP B C   1 
ATOM   3074 O O   . ASP B 2 163 ? 125.572 110.014 97.270  1.00 93.14  ? 163 ASP B O   1 
ATOM   3075 C CB  . ASP B 2 163 ? 123.932 112.139 98.016  1.00 91.52  ? 163 ASP B CB  1 
ATOM   3076 C CG  . ASP B 2 163 ? 122.587 112.511 98.568  1.00 96.77  ? 163 ASP B CG  1 
ATOM   3077 O OD1 . ASP B 2 163 ? 122.248 112.038 99.673  1.00 99.98  ? 163 ASP B OD1 1 
ATOM   3078 O OD2 . ASP B 2 163 ? 121.864 113.274 97.897  1.00 95.24  ? 163 ASP B OD2 1 
ATOM   3079 N N   . THR B 2 164 ? 127.116 110.664 98.785  1.00 85.13  ? 164 THR B N   1 
ATOM   3080 C CA  . THR B 2 164 ? 128.269 110.118 98.073  1.00 91.77  ? 164 THR B CA  1 
ATOM   3081 C C   . THR B 2 164 ? 128.459 110.796 96.720  1.00 91.53  ? 164 THR B C   1 
ATOM   3082 O O   . THR B 2 164 ? 129.046 110.220 95.802  1.00 93.54  ? 164 THR B O   1 
ATOM   3083 C CB  . THR B 2 164 ? 128.159 108.599 97.893  1.00 95.81  ? 164 THR B CB  1 
ATOM   3084 O OG1 . THR B 2 164 ? 127.276 108.312 96.803  1.00 95.39  ? 164 THR B OG1 1 
ATOM   3085 C CG2 . THR B 2 164 ? 127.621 107.940 99.156  1.00 92.00  ? 164 THR B CG2 1 
ATOM   3086 N N   . THR B 2 165 ? 127.966 112.027 96.585  1.00 83.98  ? 165 THR B N   1 
ATOM   3087 C CA  . THR B 2 165 ? 127.984 112.732 95.312  1.00 82.68  ? 165 THR B CA  1 
ATOM   3088 C C   . THR B 2 165 ? 128.436 114.171 95.506  1.00 87.04  ? 165 THR B C   1 
ATOM   3089 O O   . THR B 2 165 ? 128.192 114.788 96.548  1.00 92.31  ? 165 THR B O   1 
ATOM   3090 C CB  . THR B 2 165 ? 126.606 112.741 94.639  1.00 75.85  ? 165 THR B CB  1 
ATOM   3091 O OG1 . THR B 2 165 ? 125.654 113.362 95.510  1.00 77.25  ? 165 THR B OG1 1 
ATOM   3092 C CG2 . THR B 2 165 ? 126.147 111.330 94.326  1.00 81.88  ? 165 THR B CG2 1 
ATOM   3093 N N   . CYS B 2 166 ? 129.088 114.700 94.477  1.00 86.41  ? 166 CYS B N   1 
ATOM   3094 C CA  . CYS B 2 166 ? 129.339 116.125 94.348  1.00 78.75  ? 166 CYS B CA  1 
ATOM   3095 C C   . CYS B 2 166 ? 128.475 116.674 93.221  1.00 87.27  ? 166 CYS B C   1 
ATOM   3096 O O   . CYS B 2 166 ? 127.996 115.933 92.362  1.00 94.86  ? 166 CYS B O   1 
ATOM   3097 C CB  . CYS B 2 166 ? 130.818 116.407 94.078  1.00 74.00  ? 166 CYS B CB  1 
ATOM   3098 S SG  . CYS B 2 166 ? 131.942 115.617 95.245  1.00 90.88  ? 166 CYS B SG  1 
ATOM   3099 N N   . ALA B 2 167 ? 128.262 117.983 93.234  1.00 74.51  ? 167 ALA B N   1 
ATOM   3100 C CA  . ALA B 2 167 ? 127.394 118.603 92.247  1.00 71.72  ? 167 ALA B CA  1 
ATOM   3101 C C   . ALA B 2 167 ? 127.937 119.964 91.852  1.00 77.03  ? 167 ALA B C   1 
ATOM   3102 O O   . ALA B 2 167 ? 128.373 120.739 92.708  1.00 81.57  ? 167 ALA B O   1 
ATOM   3103 C CB  . ALA B 2 167 ? 125.965 118.747 92.777  1.00 73.09  ? 167 ALA B CB  1 
ATOM   3104 N N   . LEU B 2 168 ? 127.903 120.250 90.553  1.00 78.90  ? 168 LEU B N   1 
ATOM   3105 C CA  . LEU B 2 168 ? 128.265 121.558 90.025  1.00 75.07  ? 168 LEU B CA  1 
ATOM   3106 C C   . LEU B 2 168 ? 126.987 122.334 89.742  1.00 76.45  ? 168 LEU B C   1 
ATOM   3107 O O   . LEU B 2 168 ? 126.159 121.903 88.933  1.00 89.43  ? 168 LEU B O   1 
ATOM   3108 C CB  . LEU B 2 168 ? 129.109 121.426 88.760  1.00 76.02  ? 168 LEU B CB  1 
ATOM   3109 C CG  . LEU B 2 168 ? 129.448 122.730 88.043  1.00 78.00  ? 168 LEU B CG  1 
ATOM   3110 C CD1 . LEU B 2 168 ? 130.146 123.690 88.983  1.00 77.17  ? 168 LEU B CD1 1 
ATOM   3111 C CD2 . LEU B 2 168 ? 130.302 122.460 86.821  1.00 78.40  ? 168 LEU B CD2 1 
ATOM   3112 N N   . TRP B 2 169 ? 126.833 123.474 90.404  1.00 65.66  ? 169 TRP B N   1 
ATOM   3113 C CA  . TRP B 2 169 ? 125.617 124.267 90.368  1.00 73.08  ? 169 TRP B CA  1 
ATOM   3114 C C   . TRP B 2 169 ? 125.879 125.552 89.603  1.00 83.11  ? 169 TRP B C   1 
ATOM   3115 O O   . TRP B 2 169 ? 126.890 126.223 89.842  1.00 88.10  ? 169 TRP B O   1 
ATOM   3116 C CB  . TRP B 2 169 ? 125.153 124.614 91.781  1.00 73.99  ? 169 TRP B CB  1 
ATOM   3117 C CG  . TRP B 2 169 ? 124.884 123.448 92.654  1.00 67.78  ? 169 TRP B CG  1 
ATOM   3118 C CD1 . TRP B 2 169 ? 125.798 122.735 93.366  1.00 72.45  ? 169 TRP B CD1 1 
ATOM   3119 C CD2 . TRP B 2 169 ? 123.612 122.869 92.938  1.00 71.12  ? 169 TRP B CD2 1 
ATOM   3120 N NE1 . TRP B 2 169 ? 125.175 121.738 94.069  1.00 75.97  ? 169 TRP B NE1 1 
ATOM   3121 C CE2 . TRP B 2 169 ? 123.830 121.799 93.822  1.00 74.16  ? 169 TRP B CE2 1 
ATOM   3122 C CE3 . TRP B 2 169 ? 122.308 123.148 92.526  1.00 81.00  ? 169 TRP B CE3 1 
ATOM   3123 C CZ2 . TRP B 2 169 ? 122.796 121.010 94.302  1.00 80.32  ? 169 TRP B CZ2 1 
ATOM   3124 C CZ3 . TRP B 2 169 ? 121.285 122.364 93.002  1.00 84.65  ? 169 TRP B CZ3 1 
ATOM   3125 C CH2 . TRP B 2 169 ? 121.533 121.306 93.879  1.00 83.18  ? 169 TRP B CH2 1 
ATOM   3126 N N   . ASP B 2 170 ? 124.969 125.892 88.697  1.00 87.08  ? 170 ASP B N   1 
ATOM   3127 C CA  . ASP B 2 170 ? 124.939 127.209 88.080  1.00 84.49  ? 170 ASP B CA  1 
ATOM   3128 C C   . ASP B 2 170 ? 124.027 128.065 88.952  1.00 87.16  ? 170 ASP B C   1 
ATOM   3129 O O   . ASP B 2 170 ? 122.829 127.788 89.064  1.00 90.19  ? 170 ASP B O   1 
ATOM   3130 C CB  . ASP B 2 170 ? 124.449 127.102 86.631  1.00 83.84  ? 170 ASP B CB  1 
ATOM   3131 C CG  . ASP B 2 170 ? 123.932 128.424 86.037  1.00 94.34  ? 170 ASP B CG  1 
ATOM   3132 O OD1 . ASP B 2 170 ? 123.746 129.443 86.734  1.00 96.69  ? 170 ASP B OD1 1 
ATOM   3133 O OD2 . ASP B 2 170 ? 123.699 128.433 84.810  1.00 94.70  ? 170 ASP B OD2 1 
ATOM   3134 N N   . ILE B 2 171 ? 124.599 129.100 89.569  1.00 76.91  ? 171 ILE B N   1 
ATOM   3135 C CA  . ILE B 2 171 ? 123.869 129.871 90.570  1.00 73.24  ? 171 ILE B CA  1 
ATOM   3136 C C   . ILE B 2 171 ? 122.650 130.544 89.957  1.00 83.19  ? 171 ILE B C   1 
ATOM   3137 O O   . ILE B 2 171 ? 121.569 130.563 90.556  1.00 89.92  ? 171 ILE B O   1 
ATOM   3138 C CB  . ILE B 2 171 ? 124.801 130.899 91.233  1.00 77.11  ? 171 ILE B CB  1 
ATOM   3139 C CG1 . ILE B 2 171 ? 126.045 130.211 91.788  1.00 80.59  ? 171 ILE B CG1 1 
ATOM   3140 C CG2 . ILE B 2 171 ? 124.065 131.644 92.327  1.00 80.92  ? 171 ILE B CG2 1 
ATOM   3141 C CD1 . ILE B 2 171 ? 125.845 129.615 93.151  1.00 81.72  ? 171 ILE B CD1 1 
ATOM   3142 N N   . GLU B 2 172 ? 122.805 131.115 88.761  1.00 91.97  ? 172 GLU B N   1 
ATOM   3143 C CA  . GLU B 2 172 ? 121.721 131.885 88.161  1.00 88.13  ? 172 GLU B CA  1 
ATOM   3144 C C   . GLU B 2 172 ? 120.488 131.020 87.930  1.00 90.71  ? 172 GLU B C   1 
ATOM   3145 O O   . GLU B 2 172 ? 119.374 131.390 88.317  1.00 93.96  ? 172 GLU B O   1 
ATOM   3146 C CB  . GLU B 2 172 ? 122.193 132.517 86.852  1.00 88.95  ? 172 GLU B CB  1 
ATOM   3147 C CG  . GLU B 2 172 ? 121.073 133.070 85.991  1.00 96.00  ? 172 GLU B CG  1 
ATOM   3148 C CD  . GLU B 2 172 ? 120.835 132.244 84.743  1.00 103.97 ? 172 GLU B CD  1 
ATOM   3149 O OE1 . GLU B 2 172 ? 121.723 131.443 84.380  1.00 103.75 ? 172 GLU B OE1 1 
ATOM   3150 O OE2 . GLU B 2 172 ? 119.761 132.395 84.124  1.00 102.36 ? 172 GLU B OE2 1 
ATOM   3151 N N   . THR B 2 173 ? 120.668 129.855 87.306  1.00 86.39  ? 173 THR B N   1 
ATOM   3152 C CA  . THR B 2 173 ? 119.537 128.967 87.069  1.00 89.03  ? 173 THR B CA  1 
ATOM   3153 C C   . THR B 2 173 ? 119.126 128.214 88.325  1.00 91.07  ? 173 THR B C   1 
ATOM   3154 O O   . THR B 2 173 ? 117.942 127.908 88.499  1.00 92.81  ? 173 THR B O   1 
ATOM   3155 C CB  . THR B 2 173 ? 119.866 127.969 85.959  1.00 89.06  ? 173 THR B CB  1 
ATOM   3156 O OG1 . THR B 2 173 ? 121.121 127.340 86.239  1.00 91.06  ? 173 THR B OG1 1 
ATOM   3157 C CG2 . THR B 2 173 ? 119.948 128.676 84.618  1.00 87.12  ? 173 THR B CG2 1 
ATOM   3158 N N   . GLY B 2 174 ? 120.076 127.911 89.205  1.00 96.32  ? 174 GLY B N   1 
ATOM   3159 C CA  . GLY B 2 174 ? 119.789 127.125 90.384  1.00 94.18  ? 174 GLY B CA  1 
ATOM   3160 C C   . GLY B 2 174 ? 119.724 125.635 90.152  1.00 96.71  ? 174 GLY B C   1 
ATOM   3161 O O   . GLY B 2 174 ? 119.268 124.906 91.040  1.00 97.33  ? 174 GLY B O   1 
ATOM   3162 N N   . GLN B 2 175 ? 120.168 125.157 88.995  1.00 95.27  ? 175 GLN B N   1 
ATOM   3163 C CA  . GLN B 2 175 ? 120.094 123.751 88.637  1.00 93.27  ? 175 GLN B CA  1 
ATOM   3164 C C   . GLN B 2 175 ? 121.472 123.107 88.705  1.00 91.81  ? 175 GLN B C   1 
ATOM   3165 O O   . GLN B 2 175 ? 122.500 123.782 88.776  1.00 95.46  ? 175 GLN B O   1 
ATOM   3166 C CB  . GLN B 2 175 ? 119.503 123.574 87.234  1.00 95.38  ? 175 GLN B CB  1 
ATOM   3167 C CG  . GLN B 2 175 ? 117.979 123.774 87.074  1.00 98.68  ? 175 GLN B CG  1 
ATOM   3168 C CD  . GLN B 2 175 ? 117.119 123.284 88.241  1.00 102.39 ? 175 GLN B CD  1 
ATOM   3169 O OE1 . GLN B 2 175 ? 117.283 123.695 89.390  1.00 100.99 ? 175 GLN B OE1 1 
ATOM   3170 N NE2 . GLN B 2 175 ? 116.189 122.387 87.935  1.00 102.12 ? 175 GLN B NE2 1 
ATOM   3171 N N   . GLN B 2 176 ? 121.472 121.778 88.680  1.00 78.84  ? 176 GLN B N   1 
ATOM   3172 C CA  . GLN B 2 176 ? 122.690 120.984 88.781  1.00 76.02  ? 176 GLN B CA  1 
ATOM   3173 C C   . GLN B 2 176 ? 123.239 120.751 87.379  1.00 73.12  ? 176 GLN B C   1 
ATOM   3174 O O   . GLN B 2 176 ? 122.674 119.973 86.606  1.00 84.72  ? 176 GLN B O   1 
ATOM   3175 C CB  . GLN B 2 176 ? 122.397 119.664 89.485  1.00 79.49  ? 176 GLN B CB  1 
ATOM   3176 C CG  . GLN B 2 176 ? 122.695 119.669 90.968  1.00 83.65  ? 176 GLN B CG  1 
ATOM   3177 C CD  . GLN B 2 176 ? 122.683 118.278 91.562  1.00 90.02  ? 176 GLN B CD  1 
ATOM   3178 O OE1 . GLN B 2 176 ? 122.684 117.286 90.840  1.00 89.62  ? 176 GLN B OE1 1 
ATOM   3179 N NE2 . GLN B 2 176 ? 122.664 118.198 92.886  1.00 87.09  ? 176 GLN B NE2 1 
ATOM   3180 N N   . THR B 2 177 ? 124.337 121.431 87.046  1.00 69.06  ? 177 THR B N   1 
ATOM   3181 C CA  . THR B 2 177 ? 124.925 121.273 85.721  1.00 73.83  ? 177 THR B CA  1 
ATOM   3182 C C   . THR B 2 177 ? 125.487 119.870 85.530  1.00 78.94  ? 177 THR B C   1 
ATOM   3183 O O   . THR B 2 177 ? 125.184 119.199 84.538  1.00 86.26  ? 177 THR B O   1 
ATOM   3184 C CB  . THR B 2 177 ? 126.014 122.321 85.500  1.00 82.74  ? 177 THR B CB  1 
ATOM   3185 O OG1 . THR B 2 177 ? 125.455 123.631 85.654  1.00 88.09  ? 177 THR B OG1 1 
ATOM   3186 C CG2 . THR B 2 177 ? 126.601 122.191 84.106  1.00 81.39  ? 177 THR B CG2 1 
ATOM   3187 N N   . THR B 2 178 ? 126.307 119.407 86.472  1.00 81.60  ? 178 THR B N   1 
ATOM   3188 C CA  . THR B 2 178 ? 126.880 118.072 86.408  1.00 81.52  ? 178 THR B CA  1 
ATOM   3189 C C   . THR B 2 178 ? 126.822 117.428 87.784  1.00 85.77  ? 178 THR B C   1 
ATOM   3190 O O   . THR B 2 178 ? 126.937 118.103 88.812  1.00 93.41  ? 178 THR B O   1 
ATOM   3191 C CB  . THR B 2 178 ? 128.334 118.084 85.916  1.00 80.30  ? 178 THR B CB  1 
ATOM   3192 O OG1 . THR B 2 178 ? 129.083 119.054 86.654  1.00 87.61  ? 178 THR B OG1 1 
ATOM   3193 C CG2 . THR B 2 178 ? 128.399 118.423 84.438  1.00 81.89  ? 178 THR B CG2 1 
ATOM   3194 N N   . THR B 2 179 ? 126.644 116.110 87.789  1.00 78.14  ? 179 THR B N   1 
ATOM   3195 C CA  . THR B 2 179 ? 126.637 115.312 89.007  1.00 76.56  ? 179 THR B CA  1 
ATOM   3196 C C   . THR B 2 179 ? 127.850 114.394 88.983  1.00 80.05  ? 179 THR B C   1 
ATOM   3197 O O   . THR B 2 179 ? 127.998 113.580 88.066  1.00 90.33  ? 179 THR B O   1 
ATOM   3198 C CB  . THR B 2 179 ? 125.355 114.491 89.124  1.00 78.55  ? 179 THR B CB  1 
ATOM   3199 O OG1 . THR B 2 179 ? 125.364 113.455 88.136  1.00 88.38  ? 179 THR B OG1 1 
ATOM   3200 C CG2 . THR B 2 179 ? 124.149 115.370 88.891  1.00 77.54  ? 179 THR B CG2 1 
ATOM   3201 N N   . PHE B 2 180 ? 128.708 114.526 89.985  1.00 76.83  ? 180 PHE B N   1 
ATOM   3202 C CA  . PHE B 2 180 ? 129.911 113.718 90.116  1.00 83.29  ? 180 PHE B CA  1 
ATOM   3203 C C   . PHE B 2 180 ? 129.605 112.572 91.071  1.00 91.16  ? 180 PHE B C   1 
ATOM   3204 O O   . PHE B 2 180 ? 129.456 112.786 92.280  1.00 95.76  ? 180 PHE B O   1 
ATOM   3205 C CB  . PHE B 2 180 ? 131.070 114.571 90.623  1.00 85.41  ? 180 PHE B CB  1 
ATOM   3206 C CG  . PHE B 2 180 ? 131.263 115.846 89.857  1.00 85.43  ? 180 PHE B CG  1 
ATOM   3207 C CD1 . PHE B 2 180 ? 132.044 115.871 88.719  1.00 83.12  ? 180 PHE B CD1 1 
ATOM   3208 C CD2 . PHE B 2 180 ? 130.667 117.019 90.277  1.00 86.74  ? 180 PHE B CD2 1 
ATOM   3209 C CE1 . PHE B 2 180 ? 132.225 117.038 88.015  1.00 81.42  ? 180 PHE B CE1 1 
ATOM   3210 C CE2 . PHE B 2 180 ? 130.846 118.189 89.574  1.00 86.06  ? 180 PHE B CE2 1 
ATOM   3211 C CZ  . PHE B 2 180 ? 131.626 118.197 88.442  1.00 84.49  ? 180 PHE B CZ  1 
ATOM   3212 N N   . THR B 2 181 ? 129.504 111.362 90.525  1.00 83.39  ? 181 THR B N   1 
ATOM   3213 C CA  . THR B 2 181 ? 129.155 110.171 91.283  1.00 74.95  ? 181 THR B CA  1 
ATOM   3214 C C   . THR B 2 181 ? 130.245 109.123 91.126  1.00 74.62  ? 181 THR B C   1 
ATOM   3215 O O   . THR B 2 181 ? 130.968 109.102 90.127  1.00 80.38  ? 181 THR B O   1 
ATOM   3216 C CB  . THR B 2 181 ? 127.819 109.579 90.821  1.00 77.08  ? 181 THR B CB  1 
ATOM   3217 O OG1 . THR B 2 181 ? 127.966 109.054 89.497  1.00 76.39  ? 181 THR B OG1 1 
ATOM   3218 C CG2 . THR B 2 181 ? 126.736 110.640 90.815  1.00 81.30  ? 181 THR B CG2 1 
ATOM   3219 N N   . GLY B 2 182 ? 130.346 108.241 92.115  1.00 77.22  ? 182 GLY B N   1 
ATOM   3220 C CA  . GLY B 2 182 ? 131.357 107.205 92.084  1.00 77.39  ? 182 GLY B CA  1 
ATOM   3221 C C   . GLY B 2 182 ? 131.919 106.853 93.444  1.00 76.08  ? 182 GLY B C   1 
ATOM   3222 O O   . GLY B 2 182 ? 132.519 105.788 93.612  1.00 79.98  ? 182 GLY B O   1 
ATOM   3223 N N   . HIS B 2 183 ? 131.737 107.732 94.423  1.00 79.58  ? 183 HIS B N   1 
ATOM   3224 C CA  . HIS B 2 183 ? 132.192 107.432 95.771  1.00 81.69  ? 183 HIS B CA  1 
ATOM   3225 C C   . HIS B 2 183 ? 131.261 106.426 96.431  1.00 89.25  ? 183 HIS B C   1 
ATOM   3226 O O   . HIS B 2 183 ? 130.037 106.509 96.301  1.00 89.44  ? 183 HIS B O   1 
ATOM   3227 C CB  . HIS B 2 183 ? 132.255 108.701 96.614  1.00 80.50  ? 183 HIS B CB  1 
ATOM   3228 C CG  . HIS B 2 183 ? 133.401 109.595 96.272  1.00 81.87  ? 183 HIS B CG  1 
ATOM   3229 N ND1 . HIS B 2 183 ? 134.369 109.947 97.184  1.00 81.92  ? 183 HIS B ND1 1 
ATOM   3230 C CD2 . HIS B 2 183 ? 133.723 110.227 95.121  1.00 90.12  ? 183 HIS B CD2 1 
ATOM   3231 C CE1 . HIS B 2 183 ? 135.246 110.748 96.608  1.00 86.83  ? 183 HIS B CE1 1 
ATOM   3232 N NE2 . HIS B 2 183 ? 134.875 110.936 95.356  1.00 92.46  ? 183 HIS B NE2 1 
ATOM   3233 N N   . THR B 2 184 ? 131.850 105.461 97.137  1.00 94.23  ? 184 THR B N   1 
ATOM   3234 C CA  . THR B 2 184 ? 131.038 104.511 97.887  1.00 90.25  ? 184 THR B CA  1 
ATOM   3235 C C   . THR B 2 184 ? 130.428 105.164 99.120  1.00 90.71  ? 184 THR B C   1 
ATOM   3236 O O   . THR B 2 184 ? 129.241 104.976 99.406  1.00 93.35  ? 184 THR B O   1 
ATOM   3237 C CB  . THR B 2 184 ? 131.877 103.299 98.282  1.00 95.94  ? 184 THR B CB  1 
ATOM   3238 O OG1 . THR B 2 184 ? 132.748 102.948 97.200  1.00 97.80  ? 184 THR B OG1 1 
ATOM   3239 C CG2 . THR B 2 184 ? 130.979 102.117 98.606  1.00 97.23  ? 184 THR B CG2 1 
ATOM   3240 N N   . GLY B 2 185 ? 131.222 105.939 99.857  1.00 90.73  ? 185 GLY B N   1 
ATOM   3241 C CA  . GLY B 2 185 ? 130.754 106.612 101.047 1.00 92.67  ? 185 GLY B CA  1 
ATOM   3242 C C   . GLY B 2 185 ? 130.527 108.098 100.819 1.00 92.94  ? 185 GLY B C   1 
ATOM   3243 O O   . GLY B 2 185 ? 130.854 108.656 99.776  1.00 95.92  ? 185 GLY B O   1 
ATOM   3244 N N   . ASP B 2 186 ? 129.950 108.737 101.832 1.00 89.27  ? 186 ASP B N   1 
ATOM   3245 C CA  . ASP B 2 186 ? 129.610 110.148 101.728 1.00 87.80  ? 186 ASP B CA  1 
ATOM   3246 C C   . ASP B 2 186 ? 130.865 111.011 101.732 1.00 90.57  ? 186 ASP B C   1 
ATOM   3247 O O   . ASP B 2 186 ? 131.761 110.822 102.559 1.00 93.70  ? 186 ASP B O   1 
ATOM   3248 C CB  . ASP B 2 186 ? 128.679 110.553 102.868 1.00 89.88  ? 186 ASP B CB  1 
ATOM   3249 C CG  . ASP B 2 186 ? 129.069 109.933 104.183 1.00 95.51  ? 186 ASP B CG  1 
ATOM   3250 O OD1 . ASP B 2 186 ? 129.884 108.991 104.169 1.00 100.05 ? 186 ASP B OD1 1 
ATOM   3251 O OD2 . ASP B 2 186 ? 128.563 110.385 105.230 1.00 98.09  ? 186 ASP B OD2 1 
ATOM   3252 N N   . VAL B 2 187 ? 130.920 111.963 100.801 1.00 85.34  ? 187 VAL B N   1 
ATOM   3253 C CA  . VAL B 2 187 ? 132.076 112.841 100.676 1.00 82.90  ? 187 VAL B CA  1 
ATOM   3254 C C   . VAL B 2 187 ? 132.063 113.855 101.809 1.00 82.66  ? 187 VAL B C   1 
ATOM   3255 O O   . VAL B 2 187 ? 131.030 114.470 102.100 1.00 87.33  ? 187 VAL B O   1 
ATOM   3256 C CB  . VAL B 2 187 ? 132.074 113.534 99.308  1.00 81.79  ? 187 VAL B CB  1 
ATOM   3257 C CG1 . VAL B 2 187 ? 133.288 114.421 99.170  1.00 87.17  ? 187 VAL B CG1 1 
ATOM   3258 C CG2 . VAL B 2 187 ? 132.033 112.504 98.196  1.00 80.44  ? 187 VAL B CG2 1 
ATOM   3259 N N   . MET B 2 188 ? 133.213 114.038 102.455 1.00 85.81  ? 188 MET B N   1 
ATOM   3260 C CA  . MET B 2 188 ? 133.291 114.900 103.623 1.00 84.92  ? 188 MET B CA  1 
ATOM   3261 C C   . MET B 2 188 ? 134.070 116.186 103.397 1.00 87.76  ? 188 MET B C   1 
ATOM   3262 O O   . MET B 2 188 ? 134.013 117.076 104.252 1.00 94.76  ? 188 MET B O   1 
ATOM   3263 C CB  . MET B 2 188 ? 133.912 114.144 104.805 1.00 93.10  ? 188 MET B CB  1 
ATOM   3264 C CG  . MET B 2 188 ? 133.120 112.930 105.237 1.00 92.21  ? 188 MET B CG  1 
ATOM   3265 S SD  . MET B 2 188 ? 131.596 113.360 106.096 1.00 106.82 ? 188 MET B SD  1 
ATOM   3266 C CE  . MET B 2 188 ? 132.128 114.770 107.063 1.00 90.49  ? 188 MET B CE  1 
ATOM   3267 N N   . SER B 2 189 ? 134.791 116.317 102.290 1.00 80.46  ? 189 SER B N   1 
ATOM   3268 C CA  . SER B 2 189 ? 135.542 117.538 102.042 1.00 82.77  ? 189 SER B CA  1 
ATOM   3269 C C   . SER B 2 189 ? 135.776 117.668 100.545 1.00 89.62  ? 189 SER B C   1 
ATOM   3270 O O   . SER B 2 189 ? 135.621 116.711 99.785  1.00 91.68  ? 189 SER B O   1 
ATOM   3271 C CB  . SER B 2 189 ? 136.859 117.548 102.819 1.00 87.39  ? 189 SER B CB  1 
ATOM   3272 O OG  . SER B 2 189 ? 137.614 118.707 102.522 1.00 95.29  ? 189 SER B OG  1 
ATOM   3273 N N   . LEU B 2 190 ? 136.159 118.874 100.132 1.00 83.48  ? 190 LEU B N   1 
ATOM   3274 C CA  . LEU B 2 190 ? 136.228 119.211 98.717  1.00 73.32  ? 190 LEU B CA  1 
ATOM   3275 C C   . LEU B 2 190 ? 137.224 120.342 98.520  1.00 73.66  ? 190 LEU B C   1 
ATOM   3276 O O   . LEU B 2 190 ? 137.125 121.377 99.185  1.00 87.71  ? 190 LEU B O   1 
ATOM   3277 C CB  . LEU B 2 190 ? 134.845 119.612 98.205  1.00 75.09  ? 190 LEU B CB  1 
ATOM   3278 C CG  . LEU B 2 190 ? 134.688 119.984 96.740  1.00 76.53  ? 190 LEU B CG  1 
ATOM   3279 C CD1 . LEU B 2 190 ? 133.529 119.220 96.141  1.00 82.17  ? 190 LEU B CD1 1 
ATOM   3280 C CD2 . LEU B 2 190 ? 134.452 121.467 96.641  1.00 77.84  ? 190 LEU B CD2 1 
ATOM   3281 N N   . SER B 2 191 ? 138.179 120.145 97.615  1.00 66.24  ? 191 SER B N   1 
ATOM   3282 C CA  . SER B 2 191 ? 139.195 121.144 97.324  1.00 70.51  ? 191 SER B CA  1 
ATOM   3283 C C   . SER B 2 191 ? 139.293 121.351 95.821  1.00 74.90  ? 191 SER B C   1 
ATOM   3284 O O   . SER B 2 191 ? 139.086 120.423 95.035  1.00 90.04  ? 191 SER B O   1 
ATOM   3285 C CB  . SER B 2 191 ? 140.562 120.740 97.877  1.00 77.93  ? 191 SER B CB  1 
ATOM   3286 O OG  . SER B 2 191 ? 141.549 121.690 97.522  1.00 82.48  ? 191 SER B OG  1 
ATOM   3287 N N   . LEU B 2 192 ? 139.615 122.580 95.429  1.00 63.48  ? 192 LEU B N   1 
ATOM   3288 C CA  . LEU B 2 192 ? 139.653 122.979 94.031  1.00 60.70  ? 192 LEU B CA  1 
ATOM   3289 C C   . LEU B 2 192 ? 141.081 123.277 93.605  1.00 62.46  ? 192 LEU B C   1 
ATOM   3290 O O   . LEU B 2 192 ? 141.841 123.906 94.347  1.00 70.33  ? 192 LEU B O   1 
ATOM   3291 C CB  . LEU B 2 192 ? 138.782 124.211 93.785  1.00 62.51  ? 192 LEU B CB  1 
ATOM   3292 C CG  . LEU B 2 192 ? 137.365 123.939 93.297  1.00 65.34  ? 192 LEU B CG  1 
ATOM   3293 C CD1 . LEU B 2 192 ? 136.701 122.941 94.208  1.00 69.49  ? 192 LEU B CD1 1 
ATOM   3294 C CD2 . LEU B 2 192 ? 136.569 125.223 93.239  1.00 67.69  ? 192 LEU B CD2 1 
ATOM   3295 N N   . ALA B 2 193 ? 141.438 122.824 92.410  1.00 74.00  ? 193 ALA B N   1 
ATOM   3296 C CA  . ALA B 2 193 ? 142.753 123.114 91.874  1.00 82.03  ? 193 ALA B CA  1 
ATOM   3297 C C   . ALA B 2 193 ? 142.886 124.608 91.586  1.00 81.33  ? 193 ALA B C   1 
ATOM   3298 O O   . ALA B 2 193 ? 141.897 125.280 91.284  1.00 88.71  ? 193 ALA B O   1 
ATOM   3299 C CB  . ALA B 2 193 ? 143.001 122.313 90.601  1.00 85.63  ? 193 ALA B CB  1 
ATOM   3300 N N   . PRO B 2 194 ? 144.098 125.156 91.693  1.00 77.54  ? 194 PRO B N   1 
ATOM   3301 C CA  . PRO B 2 194 ? 144.280 126.584 91.394  1.00 81.50  ? 194 PRO B CA  1 
ATOM   3302 C C   . PRO B 2 194 ? 143.879 126.967 89.981  1.00 87.89  ? 194 PRO B C   1 
ATOM   3303 O O   . PRO B 2 194 ? 143.469 128.112 89.755  1.00 91.27  ? 194 PRO B O   1 
ATOM   3304 C CB  . PRO B 2 194 ? 145.780 126.797 91.634  1.00 81.24  ? 194 PRO B CB  1 
ATOM   3305 C CG  . PRO B 2 194 ? 146.145 125.747 92.619  1.00 81.64  ? 194 PRO B CG  1 
ATOM   3306 C CD  . PRO B 2 194 ? 145.313 124.553 92.262  1.00 78.93  ? 194 PRO B CD  1 
ATOM   3307 N N   . ASP B 2 195 ? 143.982 126.049 89.022  1.00 90.59  ? 195 ASP B N   1 
ATOM   3308 C CA  . ASP B 2 195 ? 143.578 126.340 87.653  1.00 92.41  ? 195 ASP B CA  1 
ATOM   3309 C C   . ASP B 2 195 ? 142.089 126.131 87.419  1.00 91.50  ? 195 ASP B C   1 
ATOM   3310 O O   . ASP B 2 195 ? 141.647 126.228 86.270  1.00 93.63  ? 195 ASP B O   1 
ATOM   3311 C CB  . ASP B 2 195 ? 144.373 125.477 86.670  1.00 94.59  ? 195 ASP B CB  1 
ATOM   3312 C CG  . ASP B 2 195 ? 144.553 124.055 87.156  1.00 97.89  ? 195 ASP B CG  1 
ATOM   3313 O OD1 . ASP B 2 195 ? 143.564 123.457 87.626  1.00 98.85  ? 195 ASP B OD1 1 
ATOM   3314 O OD2 . ASP B 2 195 ? 145.683 123.533 87.066  1.00 99.69  ? 195 ASP B OD2 1 
ATOM   3315 N N   . THR B 2 196 ? 141.330 125.805 88.471  1.00 88.77  ? 196 THR B N   1 
ATOM   3316 C CA  . THR B 2 196 ? 139.887 125.555 88.469  1.00 90.50  ? 196 THR B CA  1 
ATOM   3317 C C   . THR B 2 196 ? 139.449 124.648 87.321  1.00 90.67  ? 196 THR B C   1 
ATOM   3318 O O   . THR B 2 196 ? 138.288 124.680 86.901  1.00 89.83  ? 196 THR B O   1 
ATOM   3319 C CB  . THR B 2 196 ? 139.087 126.870 88.469  1.00 89.53  ? 196 THR B CB  1 
ATOM   3320 O OG1 . THR B 2 196 ? 137.706 126.577 88.704  1.00 94.27  ? 196 THR B OG1 1 
ATOM   3321 C CG2 . THR B 2 196 ? 139.192 127.633 87.151  1.00 91.82  ? 196 THR B CG2 1 
ATOM   3322 N N   . ARG B 2 197 ? 140.366 123.812 86.831  1.00 99.79  ? 197 ARG B N   1 
ATOM   3323 C CA  . ARG B 2 197 ? 140.028 122.814 85.822  1.00 95.61  ? 197 ARG B CA  1 
ATOM   3324 C C   . ARG B 2 197 ? 139.526 121.523 86.452  1.00 99.62  ? 197 ARG B C   1 
ATOM   3325 O O   . ARG B 2 197 ? 138.688 120.829 85.867  1.00 100.82 ? 197 ARG B O   1 
ATOM   3326 C CB  . ARG B 2 197 ? 141.247 122.523 84.946  1.00 98.67  ? 197 ARG B CB  1 
ATOM   3327 C CG  . ARG B 2 197 ? 141.858 123.746 84.282  1.00 99.76  ? 197 ARG B CG  1 
ATOM   3328 C CD  . ARG B 2 197 ? 140.826 124.524 83.452  1.00 100.39 ? 197 ARG B CD  1 
ATOM   3329 N NE  . ARG B 2 197 ? 139.927 123.733 82.605  1.00 103.08 ? 197 ARG B NE  1 
ATOM   3330 C CZ  . ARG B 2 197 ? 140.249 122.662 81.883  1.00 106.54 ? 197 ARG B CZ  1 
ATOM   3331 N NH1 . ARG B 2 197 ? 141.503 122.262 81.740  1.00 105.16 ? 197 ARG B NH1 1 
ATOM   3332 N NH2 . ARG B 2 197 ? 139.288 121.994 81.253  1.00 106.21 ? 197 ARG B NH2 1 
ATOM   3333 N N   . LEU B 2 198 ? 140.033 121.181 87.633  1.00 85.75  ? 198 LEU B N   1 
ATOM   3334 C CA  . LEU B 2 198 ? 139.732 119.919 88.288  1.00 75.12  ? 198 LEU B CA  1 
ATOM   3335 C C   . LEU B 2 198 ? 139.451 120.164 89.763  1.00 82.31  ? 198 LEU B C   1 
ATOM   3336 O O   . LEU B 2 198 ? 139.787 121.214 90.313  1.00 88.60  ? 198 LEU B O   1 
ATOM   3337 C CB  . LEU B 2 198 ? 140.889 118.928 88.147  1.00 71.43  ? 198 LEU B CB  1 
ATOM   3338 C CG  . LEU B 2 198 ? 141.699 118.921 86.854  1.00 78.32  ? 198 LEU B CG  1 
ATOM   3339 C CD1 . LEU B 2 198 ? 142.959 118.098 87.033  1.00 79.69  ? 198 LEU B CD1 1 
ATOM   3340 C CD2 . LEU B 2 198 ? 140.867 118.375 85.712  1.00 84.07  ? 198 LEU B CD2 1 
ATOM   3341 N N   . PHE B 2 199 ? 138.827 119.178 90.402  1.00 80.86  ? 199 PHE B N   1 
ATOM   3342 C CA  . PHE B 2 199 ? 138.615 119.244 91.842  1.00 78.40  ? 199 PHE B CA  1 
ATOM   3343 C C   . PHE B 2 199 ? 138.672 117.846 92.440  1.00 82.42  ? 199 PHE B C   1 
ATOM   3344 O O   . PHE B 2 199 ? 138.220 116.878 91.825  1.00 87.04  ? 199 PHE B O   1 
ATOM   3345 C CB  . PHE B 2 199 ? 137.290 119.939 92.183  1.00 68.70  ? 199 PHE B CB  1 
ATOM   3346 C CG  . PHE B 2 199 ? 136.084 119.058 92.070  1.00 68.08  ? 199 PHE B CG  1 
ATOM   3347 C CD1 . PHE B 2 199 ? 135.554 118.748 90.835  1.00 79.21  ? 199 PHE B CD1 1 
ATOM   3348 C CD2 . PHE B 2 199 ? 135.464 118.564 93.200  1.00 71.42  ? 199 PHE B CD2 1 
ATOM   3349 C CE1 . PHE B 2 199 ? 134.438 117.950 90.729  1.00 84.85  ? 199 PHE B CE1 1 
ATOM   3350 C CE2 . PHE B 2 199 ? 134.350 117.764 93.097  1.00 78.11  ? 199 PHE B CE2 1 
ATOM   3351 C CZ  . PHE B 2 199 ? 133.837 117.456 91.862  1.00 85.30  ? 199 PHE B CZ  1 
ATOM   3352 N N   . VAL B 2 200 ? 139.239 117.749 93.641  1.00 70.09  ? 200 VAL B N   1 
ATOM   3353 C CA  . VAL B 2 200 ? 139.442 116.481 94.330  1.00 61.05  ? 200 VAL B CA  1 
ATOM   3354 C C   . VAL B 2 200 ? 138.612 116.479 95.602  1.00 69.28  ? 200 VAL B C   1 
ATOM   3355 O O   . VAL B 2 200 ? 138.623 117.456 96.358  1.00 80.37  ? 200 VAL B O   1 
ATOM   3356 C CB  . VAL B 2 200 ? 140.926 116.240 94.653  1.00 67.04  ? 200 VAL B CB  1 
ATOM   3357 C CG1 . VAL B 2 200 ? 141.102 114.894 95.324  1.00 77.80  ? 200 VAL B CG1 1 
ATOM   3358 C CG2 . VAL B 2 200 ? 141.747 116.292 93.389  1.00 74.04  ? 200 VAL B CG2 1 
ATOM   3359 N N   . SER B 2 201 ? 137.894 115.384 95.835  1.00 76.22  ? 201 SER B N   1 
ATOM   3360 C CA  . SER B 2 201 ? 137.054 115.241 97.014  1.00 73.90  ? 201 SER B CA  1 
ATOM   3361 C C   . SER B 2 201 ? 137.279 113.880 97.654  1.00 79.58  ? 201 SER B C   1 
ATOM   3362 O O   . SER B 2 201 ? 137.372 112.870 96.955  1.00 87.26  ? 201 SER B O   1 
ATOM   3363 C CB  . SER B 2 201 ? 135.580 115.405 96.659  1.00 77.53  ? 201 SER B CB  1 
ATOM   3364 O OG  . SER B 2 201 ? 135.167 114.399 95.754  1.00 78.71  ? 201 SER B OG  1 
ATOM   3365 N N   . GLY B 2 202 ? 137.349 113.854 98.983  1.00 82.55  ? 202 GLY B N   1 
ATOM   3366 C CA  . GLY B 2 202 ? 137.559 112.628 99.733  1.00 81.23  ? 202 GLY B CA  1 
ATOM   3367 C C   . GLY B 2 202 ? 136.313 112.240 100.506 1.00 83.15  ? 202 GLY B C   1 
ATOM   3368 O O   . GLY B 2 202 ? 135.573 113.102 100.988 1.00 92.06  ? 202 GLY B O   1 
ATOM   3369 N N   . ALA B 2 203 ? 136.084 110.936 100.636 1.00 85.29  ? 203 ALA B N   1 
ATOM   3370 C CA  . ALA B 2 203 ? 134.847 110.464 101.247 1.00 87.33  ? 203 ALA B CA  1 
ATOM   3371 C C   . ALA B 2 203 ? 135.132 109.537 102.425 1.00 91.84  ? 203 ALA B C   1 
ATOM   3372 O O   . ALA B 2 203 ? 136.278 109.338 102.834 1.00 97.66  ? 203 ALA B O   1 
ATOM   3373 C CB  . ALA B 2 203 ? 133.966 109.763 100.215 1.00 93.31  ? 203 ALA B CB  1 
ATOM   3374 N N   . CYS B 2 204 ? 134.056 108.964 102.965 1.00 94.80  ? 204 CYS B N   1 
ATOM   3375 C CA  . CYS B 2 204 ? 134.140 108.032 104.078 1.00 91.92  ? 204 CYS B CA  1 
ATOM   3376 C C   . CYS B 2 204 ? 134.531 106.629 103.648 1.00 92.43  ? 204 CYS B C   1 
ATOM   3377 O O   . CYS B 2 204 ? 134.777 105.780 104.510 1.00 98.16  ? 204 CYS B O   1 
ATOM   3378 C CB  . CYS B 2 204 ? 132.809 107.984 104.829 1.00 94.01  ? 204 CYS B CB  1 
ATOM   3379 S SG  . CYS B 2 204 ? 132.464 109.458 105.809 1.00 107.29 ? 204 CYS B SG  1 
ATOM   3380 N N   . ASP B 2 205 ? 134.597 106.367 102.351 1.00 88.17  ? 205 ASP B N   1 
ATOM   3381 C CA  . ASP B 2 205 ? 135.082 105.096 101.842 1.00 91.70  ? 205 ASP B CA  1 
ATOM   3382 C C   . ASP B 2 205 ? 136.605 105.020 101.776 1.00 90.90  ? 205 ASP B C   1 
ATOM   3383 O O   . ASP B 2 205 ? 137.141 104.164 101.064 1.00 94.78  ? 205 ASP B O   1 
ATOM   3384 C CB  . ASP B 2 205 ? 134.419 104.801 100.487 1.00 93.99  ? 205 ASP B CB  1 
ATOM   3385 C CG  . ASP B 2 205 ? 135.098 105.487 99.299  1.00 100.05 ? 205 ASP B CG  1 
ATOM   3386 O OD1 . ASP B 2 205 ? 136.082 106.235 99.464  1.00 99.61  ? 205 ASP B OD1 1 
ATOM   3387 O OD2 . ASP B 2 205 ? 134.568 105.341 98.178  1.00 102.42 ? 205 ASP B OD2 1 
ATOM   3388 N N   . ALA B 2 206 ? 137.294 105.894 102.513 1.00 87.46  ? 206 ALA B N   1 
ATOM   3389 C CA  . ALA B 2 206 ? 138.755 105.905 102.590 1.00 92.94  ? 206 ALA B CA  1 
ATOM   3390 C C   . ALA B 2 206 ? 139.388 106.075 101.213 1.00 94.25  ? 206 ALA B C   1 
ATOM   3391 O O   . ALA B 2 206 ? 140.410 105.462 100.899 1.00 96.14  ? 206 ALA B O   1 
ATOM   3392 C CB  . ALA B 2 206 ? 139.285 104.645 103.279 1.00 93.13  ? 206 ALA B CB  1 
ATOM   3393 N N   . SER B 2 207 ? 138.779 106.916 100.383 1.00 84.23  ? 207 SER B N   1 
ATOM   3394 C CA  . SER B 2 207 ? 139.325 107.213 99.070  1.00 83.27  ? 207 SER B CA  1 
ATOM   3395 C C   . SER B 2 207 ? 138.996 108.646 98.686  1.00 86.13  ? 207 SER B C   1 
ATOM   3396 O O   . SER B 2 207 ? 137.993 109.220 99.130  1.00 89.87  ? 207 SER B O   1 
ATOM   3397 C CB  . SER B 2 207 ? 138.793 106.254 98.001  1.00 87.65  ? 207 SER B CB  1 
ATOM   3398 O OG  . SER B 2 207 ? 137.494 106.635 97.589  1.00 88.66  ? 207 SER B OG  1 
ATOM   3399 N N   . ALA B 2 208 ? 139.856 109.211 97.843  1.00 73.25  ? 208 ALA B N   1 
ATOM   3400 C CA  . ALA B 2 208 ? 139.682 110.556 97.319  1.00 71.34  ? 208 ALA B CA  1 
ATOM   3401 C C   . ALA B 2 208 ? 139.719 110.493 95.803  1.00 72.20  ? 208 ALA B C   1 
ATOM   3402 O O   . ALA B 2 208 ? 140.633 109.898 95.227  1.00 78.06  ? 208 ALA B O   1 
ATOM   3403 C CB  . ALA B 2 208 ? 140.765 111.502 97.841  1.00 75.67  ? 208 ALA B CB  1 
ATOM   3404 N N   . LYS B 2 209 ? 138.738 111.108 95.159  1.00 70.91  ? 209 LYS B N   1 
ATOM   3405 C CA  . LYS B 2 209 ? 138.618 111.068 93.712  1.00 68.92  ? 209 LYS B CA  1 
ATOM   3406 C C   . LYS B 2 209 ? 138.851 112.449 93.121  1.00 75.78  ? 209 LYS B C   1 
ATOM   3407 O O   . LYS B 2 209 ? 138.392 113.461 93.664  1.00 84.94  ? 209 LYS B O   1 
ATOM   3408 C CB  . LYS B 2 209 ? 137.251 110.535 93.288  1.00 69.78  ? 209 LYS B CB  1 
ATOM   3409 C CG  . LYS B 2 209 ? 137.032 109.082 93.661  1.00 72.78  ? 209 LYS B CG  1 
ATOM   3410 C CD  . LYS B 2 209 ? 135.774 108.522 93.034  1.00 74.81  ? 209 LYS B CD  1 
ATOM   3411 C CE  . LYS B 2 209 ? 135.472 107.139 93.575  1.00 78.88  ? 209 LYS B CE  1 
ATOM   3412 N NZ  . LYS B 2 209 ? 136.495 106.147 93.148  1.00 82.55  ? 209 LYS B NZ  1 
ATOM   3413 N N   . LEU B 2 210 ? 139.577 112.469 92.008  1.00 73.14  ? 210 LEU B N   1 
ATOM   3414 C CA  . LEU B 2 210 ? 139.888 113.675 91.257  1.00 64.37  ? 210 LEU B CA  1 
ATOM   3415 C C   . LEU B 2 210 ? 139.010 113.695 90.014  1.00 75.45  ? 210 LEU B C   1 
ATOM   3416 O O   . LEU B 2 210 ? 139.052 112.755 89.210  1.00 83.35  ? 210 LEU B O   1 
ATOM   3417 C CB  . LEU B 2 210 ? 141.365 113.691 90.869  1.00 67.17  ? 210 LEU B CB  1 
ATOM   3418 C CG  . LEU B 2 210 ? 141.746 114.442 89.595  1.00 75.06  ? 210 LEU B CG  1 
ATOM   3419 C CD1 . LEU B 2 210 ? 141.498 115.924 89.764  1.00 78.94  ? 210 LEU B CD1 1 
ATOM   3420 C CD2 . LEU B 2 210 ? 143.182 114.165 89.194  1.00 78.66  ? 210 LEU B CD2 1 
ATOM   3421 N N   . TRP B 2 211 ? 138.232 114.767 89.855  1.00 77.05  ? 211 TRP B N   1 
ATOM   3422 C CA  . TRP B 2 211 ? 137.282 114.905 88.764  1.00 78.27  ? 211 TRP B CA  1 
ATOM   3423 C C   . TRP B 2 211 ? 137.620 116.129 87.927  1.00 83.42  ? 211 TRP B C   1 
ATOM   3424 O O   . TRP B 2 211 ? 138.201 117.102 88.422  1.00 86.31  ? 211 TRP B O   1 
ATOM   3425 C CB  . TRP B 2 211 ? 135.838 115.066 89.260  1.00 75.09  ? 211 TRP B CB  1 
ATOM   3426 C CG  . TRP B 2 211 ? 135.460 114.299 90.481  1.00 72.39  ? 211 TRP B CG  1 
ATOM   3427 C CD1 . TRP B 2 211 ? 135.960 114.454 91.737  1.00 73.91  ? 211 TRP B CD1 1 
ATOM   3428 C CD2 . TRP B 2 211 ? 134.490 113.253 90.561  1.00 78.09  ? 211 TRP B CD2 1 
ATOM   3429 N NE1 . TRP B 2 211 ? 135.359 113.572 92.597  1.00 77.35  ? 211 TRP B NE1 1 
ATOM   3430 C CE2 . TRP B 2 211 ? 134.453 112.821 91.897  1.00 76.69  ? 211 TRP B CE2 1 
ATOM   3431 C CE3 . TRP B 2 211 ? 133.653 112.637 89.631  1.00 82.26  ? 211 TRP B CE3 1 
ATOM   3432 C CZ2 . TRP B 2 211 ? 133.612 111.805 92.326  1.00 80.94  ? 211 TRP B CZ2 1 
ATOM   3433 C CZ3 . TRP B 2 211 ? 132.817 111.629 90.060  1.00 79.67  ? 211 TRP B CZ3 1 
ATOM   3434 C CH2 . TRP B 2 211 ? 132.802 111.223 91.395  1.00 80.90  ? 211 TRP B CH2 1 
ATOM   3435 N N   . ASP B 2 212 ? 137.231 116.073 86.656  1.00 91.96  ? 212 ASP B N   1 
ATOM   3436 C CA  . ASP B 2 212 ? 137.236 117.237 85.786  1.00 91.61  ? 212 ASP B CA  1 
ATOM   3437 C C   . ASP B 2 212 ? 135.890 117.929 85.938  1.00 96.54  ? 212 ASP B C   1 
ATOM   3438 O O   . ASP B 2 212 ? 134.839 117.285 85.895  1.00 97.46  ? 212 ASP B O   1 
ATOM   3439 C CB  . ASP B 2 212 ? 137.502 116.813 84.334  1.00 93.64  ? 212 ASP B CB  1 
ATOM   3440 C CG  . ASP B 2 212 ? 137.181 117.900 83.294  1.00 103.75 ? 212 ASP B CG  1 
ATOM   3441 O OD1 . ASP B 2 212 ? 136.238 118.706 83.440  1.00 102.36 ? 212 ASP B OD1 1 
ATOM   3442 O OD2 . ASP B 2 212 ? 137.927 117.951 82.295  1.00 106.18 ? 212 ASP B OD2 1 
ATOM   3443 N N   . VAL B 2 213 ? 135.928 119.251 86.112  1.00 92.58  ? 213 VAL B N   1 
ATOM   3444 C CA  . VAL B 2 213 ? 134.711 119.998 86.408  1.00 89.63  ? 213 VAL B CA  1 
ATOM   3445 C C   . VAL B 2 213 ? 133.736 120.045 85.239  1.00 93.04  ? 213 VAL B C   1 
ATOM   3446 O O   . VAL B 2 213 ? 132.522 119.962 85.458  1.00 98.74  ? 213 VAL B O   1 
ATOM   3447 C CB  . VAL B 2 213 ? 135.049 121.428 86.857  1.00 92.18  ? 213 VAL B CB  1 
ATOM   3448 C CG1 . VAL B 2 213 ? 133.859 122.052 87.560  1.00 95.13  ? 213 VAL B CG1 1 
ATOM   3449 C CG2 . VAL B 2 213 ? 136.254 121.421 87.776  1.00 93.35  ? 213 VAL B CG2 1 
ATOM   3450 N N   . ARG B 2 214 ? 134.217 120.178 84.004  1.00 99.54  ? 214 ARG B N   1 
ATOM   3451 C CA  . ARG B 2 214 ? 133.320 120.331 82.863  1.00 102.73 ? 214 ARG B CA  1 
ATOM   3452 C C   . ARG B 2 214 ? 132.950 119.013 82.194  1.00 105.21 ? 214 ARG B C   1 
ATOM   3453 O O   . ARG B 2 214 ? 131.841 118.891 81.668  1.00 107.84 ? 214 ARG B O   1 
ATOM   3454 C CB  . ARG B 2 214 ? 133.926 121.286 81.829  1.00 104.54 ? 214 ARG B CB  1 
ATOM   3455 C CG  . ARG B 2 214 ? 135.121 120.752 81.065  1.00 104.50 ? 214 ARG B CG  1 
ATOM   3456 C CD  . ARG B 2 214 ? 135.921 121.903 80.480  1.00 105.80 ? 214 ARG B CD  1 
ATOM   3457 N NE  . ARG B 2 214 ? 136.148 122.963 81.456  1.00 109.01 ? 214 ARG B NE  1 
ATOM   3458 C CZ  . ARG B 2 214 ? 136.959 123.995 81.267  1.00 109.60 ? 214 ARG B CZ  1 
ATOM   3459 N NH1 . ARG B 2 214 ? 137.629 124.150 80.137  1.00 107.89 ? 214 ARG B NH1 1 
ATOM   3460 N NH2 . ARG B 2 214 ? 137.097 124.896 82.235  1.00 107.55 ? 214 ARG B NH2 1 
ATOM   3461 N N   . GLU B 2 215 ? 133.842 118.020 82.195  1.00 107.25 ? 215 GLU B N   1 
ATOM   3462 C CA  . GLU B 2 215 ? 133.472 116.718 81.650  1.00 108.35 ? 215 GLU B CA  1 
ATOM   3463 C C   . GLU B 2 215 ? 132.515 115.974 82.571  1.00 109.09 ? 215 GLU B C   1 
ATOM   3464 O O   . GLU B 2 215 ? 131.628 115.259 82.094  1.00 109.55 ? 215 GLU B O   1 
ATOM   3465 C CB  . GLU B 2 215 ? 134.722 115.879 81.383  1.00 108.42 ? 215 GLU B CB  1 
ATOM   3466 C CG  . GLU B 2 215 ? 135.800 116.473 80.443  1.00 110.78 ? 215 GLU B CG  1 
ATOM   3467 C CD  . GLU B 2 215 ? 135.325 117.510 79.415  1.00 113.12 ? 215 GLU B CD  1 
ATOM   3468 O OE1 . GLU B 2 215 ? 134.152 117.504 78.983  1.00 115.78 ? 215 GLU B OE1 1 
ATOM   3469 O OE2 . GLU B 2 215 ? 136.159 118.356 79.028  1.00 111.74 ? 215 GLU B OE2 1 
ATOM   3470 N N   . GLY B 2 216 ? 132.673 116.130 83.882  1.00 106.02 ? 216 GLY B N   1 
ATOM   3471 C CA  . GLY B 2 216 ? 131.751 115.521 84.819  1.00 105.05 ? 216 GLY B CA  1 
ATOM   3472 C C   . GLY B 2 216 ? 131.967 114.049 85.075  1.00 101.79 ? 216 GLY B C   1 
ATOM   3473 O O   . GLY B 2 216 ? 131.014 113.343 85.419  1.00 103.77 ? 216 GLY B O   1 
ATOM   3474 N N   . MET B 2 217 ? 133.193 113.559 84.920  1.00 93.19  ? 217 MET B N   1 
ATOM   3475 C CA  . MET B 2 217 ? 133.503 112.160 85.160  1.00 94.78  ? 217 MET B CA  1 
ATOM   3476 C C   . MET B 2 217 ? 134.754 112.050 86.018  1.00 94.55  ? 217 MET B C   1 
ATOM   3477 O O   . MET B 2 217 ? 135.647 112.898 85.956  1.00 96.53  ? 217 MET B O   1 
ATOM   3478 C CB  . MET B 2 217 ? 133.686 111.394 83.843  1.00 96.38  ? 217 MET B CB  1 
ATOM   3479 C CG  . MET B 2 217 ? 134.739 111.970 82.916  1.00 99.23  ? 217 MET B CG  1 
ATOM   3480 S SD  . MET B 2 217 ? 136.381 111.280 83.187  1.00 112.32 ? 217 MET B SD  1 
ATOM   3481 C CE  . MET B 2 217 ? 137.364 112.350 82.144  1.00 98.18  ? 217 MET B CE  1 
ATOM   3482 N N   . CYS B 2 218 ? 134.806 110.991 86.823  1.00 85.26  ? 218 CYS B N   1 
ATOM   3483 C CA  . CYS B 2 218 ? 135.910 110.778 87.752  1.00 80.76  ? 218 CYS B CA  1 
ATOM   3484 C C   . CYS B 2 218 ? 137.178 110.456 86.976  1.00 79.93  ? 218 CYS B C   1 
ATOM   3485 O O   . CYS B 2 218 ? 137.314 109.362 86.420  1.00 84.38  ? 218 CYS B O   1 
ATOM   3486 C CB  . CYS B 2 218 ? 135.568 109.657 88.726  1.00 84.49  ? 218 CYS B CB  1 
ATOM   3487 S SG  . CYS B 2 218 ? 136.969 109.068 89.696  1.00 105.10 ? 218 CYS B SG  1 
ATOM   3488 N N   . ARG B 2 219 ? 138.109 111.408 86.936  1.00 75.65  ? 219 ARG B N   1 
ATOM   3489 C CA  . ARG B 2 219 ? 139.350 111.190 86.204  1.00 74.07  ? 219 ARG B CA  1 
ATOM   3490 C C   . ARG B 2 219 ? 140.230 110.164 86.905  1.00 75.72  ? 219 ARG B C   1 
ATOM   3491 O O   . ARG B 2 219 ? 140.741 109.235 86.270  1.00 80.03  ? 219 ARG B O   1 
ATOM   3492 C CB  . ARG B 2 219 ? 140.097 112.512 86.030  1.00 78.90  ? 219 ARG B CB  1 
ATOM   3493 C CG  . ARG B 2 219 ? 141.513 112.356 85.508  1.00 81.69  ? 219 ARG B CG  1 
ATOM   3494 C CD  . ARG B 2 219 ? 141.949 113.567 84.702  1.00 80.32  ? 219 ARG B CD  1 
ATOM   3495 N NE  . ARG B 2 219 ? 141.635 113.425 83.286  1.00 84.11  ? 219 ARG B NE  1 
ATOM   3496 C CZ  . ARG B 2 219 ? 140.524 113.870 82.716  1.00 84.19  ? 219 ARG B CZ  1 
ATOM   3497 N NH1 . ARG B 2 219 ? 139.591 114.492 83.416  1.00 83.69  ? 219 ARG B NH1 1 
ATOM   3498 N NH2 . ARG B 2 219 ? 140.347 113.688 81.411  1.00 81.39  ? 219 ARG B NH2 1 
ATOM   3499 N N   . GLN B 2 220 ? 140.416 110.309 88.216  1.00 79.22  ? 220 GLN B N   1 
ATOM   3500 C CA  . GLN B 2 220 ? 141.288 109.404 88.955  1.00 73.52  ? 220 GLN B CA  1 
ATOM   3501 C C   . GLN B 2 220 ? 140.693 109.108 90.321  1.00 78.79  ? 220 GLN B C   1 
ATOM   3502 O O   . GLN B 2 220 ? 139.874 109.865 90.842  1.00 88.15  ? 220 GLN B O   1 
ATOM   3503 C CB  . GLN B 2 220 ? 142.698 109.981 89.130  1.00 69.39  ? 220 GLN B CB  1 
ATOM   3504 C CG  . GLN B 2 220 ? 143.438 110.240 87.837  1.00 78.82  ? 220 GLN B CG  1 
ATOM   3505 C CD  . GLN B 2 220 ? 144.890 110.589 88.066  1.00 85.30  ? 220 GLN B CD  1 
ATOM   3506 O OE1 . GLN B 2 220 ? 145.462 110.259 89.102  1.00 86.03  ? 220 GLN B OE1 1 
ATOM   3507 N NE2 . GLN B 2 220 ? 145.496 111.266 87.098  1.00 86.87  ? 220 GLN B NE2 1 
ATOM   3508 N N   . THR B 2 221 ? 141.128 107.994 90.903  1.00 73.49  ? 221 THR B N   1 
ATOM   3509 C CA  . THR B 2 221 ? 140.764 107.630 92.265  1.00 76.54  ? 221 THR B CA  1 
ATOM   3510 C C   . THR B 2 221 ? 142.011 107.194 93.019  1.00 73.02  ? 221 THR B C   1 
ATOM   3511 O O   . THR B 2 221 ? 142.845 106.456 92.486  1.00 79.53  ? 221 THR B O   1 
ATOM   3512 C CB  . THR B 2 221 ? 139.709 106.518 92.291  1.00 76.84  ? 221 THR B CB  1 
ATOM   3513 O OG1 . THR B 2 221 ? 139.536 106.053 93.635  1.00 73.48  ? 221 THR B OG1 1 
ATOM   3514 C CG2 . THR B 2 221 ? 140.120 105.357 91.397  1.00 81.52  ? 221 THR B CG2 1 
ATOM   3515 N N   . PHE B 2 222 ? 142.138 107.660 94.258  1.00 71.55  ? 222 PHE B N   1 
ATOM   3516 C CA  . PHE B 2 222 ? 143.301 107.400 95.088  1.00 79.40  ? 222 PHE B CA  1 
ATOM   3517 C C   . PHE B 2 222 ? 142.842 106.788 96.399  1.00 89.32  ? 222 PHE B C   1 
ATOM   3518 O O   . PHE B 2 222 ? 141.850 107.231 96.988  1.00 91.09  ? 222 PHE B O   1 
ATOM   3519 C CB  . PHE B 2 222 ? 144.088 108.682 95.374  1.00 81.92  ? 222 PHE B CB  1 
ATOM   3520 C CG  . PHE B 2 222 ? 144.297 109.554 94.172  1.00 80.90  ? 222 PHE B CG  1 
ATOM   3521 C CD1 . PHE B 2 222 ? 143.348 110.490 93.807  1.00 87.44  ? 222 PHE B CD1 1 
ATOM   3522 C CD2 . PHE B 2 222 ? 145.448 109.452 93.421  1.00 81.37  ? 222 PHE B CD2 1 
ATOM   3523 C CE1 . PHE B 2 222 ? 143.540 111.297 92.710  1.00 88.99  ? 222 PHE B CE1 1 
ATOM   3524 C CE2 . PHE B 2 222 ? 145.645 110.256 92.322  1.00 85.10  ? 222 PHE B CE2 1 
ATOM   3525 C CZ  . PHE B 2 222 ? 144.689 111.180 91.967  1.00 89.75  ? 222 PHE B CZ  1 
ATOM   3526 N N   . THR B 2 223 ? 143.577 105.778 96.856  1.00 88.23  ? 223 THR B N   1 
ATOM   3527 C CA  . THR B 2 223 ? 143.262 105.081 98.091  1.00 83.10  ? 223 THR B CA  1 
ATOM   3528 C C   . THR B 2 223 ? 144.551 104.824 98.856  1.00 83.82  ? 223 THR B C   1 
ATOM   3529 O O   . THR B 2 223 ? 145.654 105.057 98.358  1.00 85.07  ? 223 THR B O   1 
ATOM   3530 C CB  . THR B 2 223 ? 142.524 103.765 97.823  1.00 84.64  ? 223 THR B CB  1 
ATOM   3531 O OG1 . THR B 2 223 ? 142.121 103.181 99.067  1.00 90.32  ? 223 THR B OG1 1 
ATOM   3532 C CG2 . THR B 2 223 ? 143.428 102.795 97.081  1.00 84.63  ? 223 THR B CG2 1 
ATOM   3533 N N   . GLY B 2 224 ? 144.398 104.328 100.079 1.00 85.93  ? 224 GLY B N   1 
ATOM   3534 C CA  . GLY B 2 224 ? 145.532 104.079 100.944 1.00 87.04  ? 224 GLY B CA  1 
ATOM   3535 C C   . GLY B 2 224 ? 145.217 104.379 102.393 1.00 87.10  ? 224 GLY B C   1 
ATOM   3536 O O   . GLY B 2 224 ? 145.938 103.952 103.298 1.00 89.63  ? 224 GLY B O   1 
ATOM   3537 N N   . HIS B 2 225 ? 144.138 105.118 102.621 1.00 80.59  ? 225 HIS B N   1 
ATOM   3538 C CA  . HIS B 2 225 ? 143.696 105.412 103.972 1.00 82.31  ? 225 HIS B CA  1 
ATOM   3539 C C   . HIS B 2 225 ? 142.881 104.251 104.529 1.00 85.89  ? 225 HIS B C   1 
ATOM   3540 O O   . HIS B 2 225 ? 142.373 103.402 103.793 1.00 87.04  ? 225 HIS B O   1 
ATOM   3541 C CB  . HIS B 2 225 ? 142.867 106.692 104.000 1.00 86.77  ? 225 HIS B CB  1 
ATOM   3542 C CG  . HIS B 2 225 ? 143.677 107.935 104.190 1.00 86.54  ? 225 HIS B CG  1 
ATOM   3543 N ND1 . HIS B 2 225 ? 144.035 108.405 105.434 1.00 83.03  ? 225 HIS B ND1 1 
ATOM   3544 C CD2 . HIS B 2 225 ? 144.193 108.808 103.295 1.00 87.47  ? 225 HIS B CD2 1 
ATOM   3545 C CE1 . HIS B 2 225 ? 144.738 109.515 105.297 1.00 82.16  ? 225 HIS B CE1 1 
ATOM   3546 N NE2 . HIS B 2 225 ? 144.847 109.782 104.009 1.00 85.89  ? 225 HIS B NE2 1 
ATOM   3547 N N   . GLU B 2 226 ? 142.755 104.227 105.854 1.00 93.70  ? 226 GLU B N   1 
ATOM   3548 C CA  . GLU B 2 226 ? 142.039 103.166 106.543 1.00 91.03  ? 226 GLU B CA  1 
ATOM   3549 C C   . GLU B 2 226 ? 140.707 103.611 107.124 1.00 90.41  ? 226 GLU B C   1 
ATOM   3550 O O   . GLU B 2 226 ? 139.924 102.757 107.551 1.00 94.90  ? 226 GLU B O   1 
ATOM   3551 C CB  . GLU B 2 226 ? 142.908 102.584 107.666 1.00 94.61  ? 226 GLU B CB  1 
ATOM   3552 C CG  . GLU B 2 226 ? 144.181 101.921 107.176 1.00 96.00  ? 226 GLU B CG  1 
ATOM   3553 C CD  . GLU B 2 226 ? 145.275 101.920 108.223 1.00 101.70 ? 226 GLU B CD  1 
ATOM   3554 O OE1 . GLU B 2 226 ? 144.947 101.923 109.427 1.00 102.81 ? 226 GLU B OE1 1 
ATOM   3555 O OE2 . GLU B 2 226 ? 146.464 101.917 107.842 1.00 103.42 ? 226 GLU B OE2 1 
ATOM   3556 N N   . SER B 2 227 ? 140.428 104.909 107.156 1.00 87.90  ? 227 SER B N   1 
ATOM   3557 C CA  . SER B 2 227 ? 139.184 105.417 107.713 1.00 90.89  ? 227 SER B CA  1 
ATOM   3558 C C   . SER B 2 227 ? 138.679 106.535 106.810 1.00 93.27  ? 227 SER B C   1 
ATOM   3559 O O   . SER B 2 227 ? 139.239 106.801 105.743 1.00 98.16  ? 227 SER B O   1 
ATOM   3560 C CB  . SER B 2 227 ? 139.386 105.883 109.159 1.00 96.98  ? 227 SER B CB  1 
ATOM   3561 O OG  . SER B 2 227 ? 140.236 104.997 109.865 1.00 100.36 ? 227 SER B OG  1 
ATOM   3562 N N   . ASP B 2 228 ? 137.614 107.197 107.249 1.00 88.41  ? 228 ASP B N   1 
ATOM   3563 C CA  . ASP B 2 228 ? 136.978 108.224 106.438 1.00 87.22  ? 228 ASP B CA  1 
ATOM   3564 C C   . ASP B 2 228 ? 137.886 109.435 106.254 1.00 92.48  ? 228 ASP B C   1 
ATOM   3565 O O   . ASP B 2 228 ? 138.611 109.836 107.166 1.00 99.27  ? 228 ASP B O   1 
ATOM   3566 C CB  . ASP B 2 228 ? 135.650 108.637 107.072 1.00 89.42  ? 228 ASP B CB  1 
ATOM   3567 C CG  . ASP B 2 228 ? 135.759 108.896 108.554 1.00 93.49  ? 228 ASP B CG  1 
ATOM   3568 O OD1 . ASP B 2 228 ? 136.881 109.101 109.048 1.00 99.05  ? 228 ASP B OD1 1 
ATOM   3569 O OD2 . ASP B 2 228 ? 134.713 108.882 109.234 1.00 92.88  ? 228 ASP B OD2 1 
ATOM   3570 N N   . ILE B 2 229 ? 137.846 110.013 105.057 1.00 82.25  ? 229 ILE B N   1 
ATOM   3571 C CA  . ILE B 2 229 ? 138.615 111.210 104.738 1.00 75.58  ? 229 ILE B CA  1 
ATOM   3572 C C   . ILE B 2 229 ? 137.799 112.416 105.182 1.00 79.54  ? 229 ILE B C   1 
ATOM   3573 O O   . ILE B 2 229 ? 136.801 112.767 104.549 1.00 82.66  ? 229 ILE B O   1 
ATOM   3574 C CB  . ILE B 2 229 ? 138.944 111.289 103.244 1.00 72.97  ? 229 ILE B CB  1 
ATOM   3575 C CG1 . ILE B 2 229 ? 139.544 109.974 102.761 1.00 75.73  ? 229 ILE B CG1 1 
ATOM   3576 C CG2 . ILE B 2 229 ? 139.902 112.427 102.973 1.00 76.87  ? 229 ILE B CG2 1 
ATOM   3577 C CD1 . ILE B 2 229 ? 140.924 109.734 103.270 1.00 77.63  ? 229 ILE B CD1 1 
ATOM   3578 N N   . ASN B 2 230 ? 138.220 113.053 106.271 1.00 82.72  ? 230 ASN B N   1 
ATOM   3579 C CA  . ASN B 2 230 ? 137.500 114.198 106.804 1.00 82.91  ? 230 ASN B CA  1 
ATOM   3580 C C   . ASN B 2 230 ? 137.979 115.521 106.231 1.00 84.37  ? 230 ASN B C   1 
ATOM   3581 O O   . ASN B 2 230 ? 137.336 116.548 106.469 1.00 88.18  ? 230 ASN B O   1 
ATOM   3582 C CB  . ASN B 2 230 ? 137.629 114.241 108.328 1.00 86.46  ? 230 ASN B CB  1 
ATOM   3583 C CG  . ASN B 2 230 ? 136.783 113.194 109.013 1.00 92.61  ? 230 ASN B CG  1 
ATOM   3584 O OD1 . ASN B 2 230 ? 135.579 113.372 109.188 1.00 96.43  ? 230 ASN B OD1 1 
ATOM   3585 N ND2 . ASN B 2 230 ? 137.410 112.094 109.409 1.00 90.51  ? 230 ASN B ND2 1 
ATOM   3586 N N   . ALA B 2 231 ? 139.077 115.524 105.481 1.00 78.24  ? 231 ALA B N   1 
ATOM   3587 C CA  . ALA B 2 231 ? 139.659 116.766 105.005 1.00 70.40  ? 231 ALA B CA  1 
ATOM   3588 C C   . ALA B 2 231 ? 140.400 116.522 103.702 1.00 73.32  ? 231 ALA B C   1 
ATOM   3589 O O   . ALA B 2 231 ? 140.911 115.427 103.452 1.00 87.79  ? 231 ALA B O   1 
ATOM   3590 C CB  . ALA B 2 231 ? 140.610 117.368 106.041 1.00 74.86  ? 231 ALA B CB  1 
ATOM   3591 N N   . ILE B 2 232 ? 140.455 117.564 102.878 1.00 68.64  ? 232 ILE B N   1 
ATOM   3592 C CA  . ILE B 2 232 ? 141.173 117.532 101.612 1.00 68.82  ? 232 ILE B CA  1 
ATOM   3593 C C   . ILE B 2 232 ? 141.711 118.931 101.364 1.00 75.48  ? 232 ILE B C   1 
ATOM   3594 O O   . ILE B 2 232 ? 141.132 119.925 101.810 1.00 82.86  ? 232 ILE B O   1 
ATOM   3595 C CB  . ILE B 2 232 ? 140.265 117.062 100.451 1.00 69.87  ? 232 ILE B CB  1 
ATOM   3596 C CG1 . ILE B 2 232 ? 141.082 116.775 99.200  1.00 71.18  ? 232 ILE B CG1 1 
ATOM   3597 C CG2 . ILE B 2 232 ? 139.235 118.100 100.123 1.00 79.41  ? 232 ILE B CG2 1 
ATOM   3598 C CD1 . ILE B 2 232 ? 142.000 115.622 99.363  1.00 74.31  ? 232 ILE B CD1 1 
ATOM   3599 N N   . CYS B 2 233 ? 142.846 119.008 100.678 1.00 77.10  ? 233 CYS B N   1 
ATOM   3600 C CA  . CYS B 2 233 ? 143.435 120.295 100.349 1.00 73.00  ? 233 CYS B CA  1 
ATOM   3601 C C   . CYS B 2 233 ? 144.358 120.117 99.159  1.00 69.51  ? 233 CYS B C   1 
ATOM   3602 O O   . CYS B 2 233 ? 145.117 119.148 99.095  1.00 79.50  ? 233 CYS B O   1 
ATOM   3603 C CB  . CYS B 2 233 ? 144.206 120.882 101.533 1.00 81.69  ? 233 CYS B CB  1 
ATOM   3604 S SG  . CYS B 2 233 ? 145.506 122.039 101.064 1.00 105.75 ? 233 CYS B SG  1 
ATOM   3605 N N   . PHE B 2 234 ? 144.291 121.056 98.224  1.00 62.72  ? 234 PHE B N   1 
ATOM   3606 C CA  . PHE B 2 234 ? 145.106 121.004 97.021  1.00 61.97  ? 234 PHE B CA  1 
ATOM   3607 C C   . PHE B 2 234 ? 146.466 121.632 97.281  1.00 64.43  ? 234 PHE B C   1 
ATOM   3608 O O   . PHE B 2 234 ? 146.568 122.655 97.964  1.00 68.94  ? 234 PHE B O   1 
ATOM   3609 C CB  . PHE B 2 234 ? 144.414 121.726 95.867  1.00 71.12  ? 234 PHE B CB  1 
ATOM   3610 C CG  . PHE B 2 234 ? 144.097 120.840 94.702  1.00 66.82  ? 234 PHE B CG  1 
ATOM   3611 C CD1 . PHE B 2 234 ? 145.091 120.436 93.832  1.00 66.60  ? 234 PHE B CD1 1 
ATOM   3612 C CD2 . PHE B 2 234 ? 142.802 120.426 94.468  1.00 66.67  ? 234 PHE B CD2 1 
ATOM   3613 C CE1 . PHE B 2 234 ? 144.800 119.627 92.760  1.00 63.07  ? 234 PHE B CE1 1 
ATOM   3614 C CE2 . PHE B 2 234 ? 142.509 119.622 93.398  1.00 68.97  ? 234 PHE B CE2 1 
ATOM   3615 C CZ  . PHE B 2 234 ? 143.510 119.221 92.542  1.00 61.80  ? 234 PHE B CZ  1 
ATOM   3616 N N   . PHE B 2 235 ? 147.504 121.012 96.742  1.00 75.89  ? 235 PHE B N   1 
ATOM   3617 C CA  . PHE B 2 235 ? 148.812 121.641 96.720  1.00 78.94  ? 235 PHE B CA  1 
ATOM   3618 C C   . PHE B 2 235 ? 148.746 122.892 95.845  1.00 84.66  ? 235 PHE B C   1 
ATOM   3619 O O   . PHE B 2 235 ? 148.023 122.905 94.842  1.00 88.68  ? 235 PHE B O   1 
ATOM   3620 C CB  . PHE B 2 235 ? 149.850 120.660 96.172  1.00 77.64  ? 235 PHE B CB  1 
ATOM   3621 C CG  . PHE B 2 235 ? 151.258 120.972 96.568  1.00 77.01  ? 235 PHE B CG  1 
ATOM   3622 C CD1 . PHE B 2 235 ? 151.758 120.547 97.780  1.00 73.95  ? 235 PHE B CD1 1 
ATOM   3623 C CD2 . PHE B 2 235 ? 152.086 121.680 95.721  1.00 81.74  ? 235 PHE B CD2 1 
ATOM   3624 C CE1 . PHE B 2 235 ? 153.054 120.827 98.142  1.00 74.67  ? 235 PHE B CE1 1 
ATOM   3625 C CE2 . PHE B 2 235 ? 153.379 121.971 96.082  1.00 81.63  ? 235 PHE B CE2 1 
ATOM   3626 C CZ  . PHE B 2 235 ? 153.865 121.539 97.291  1.00 76.82  ? 235 PHE B CZ  1 
ATOM   3627 N N   . PRO B 2 236 ? 149.465 123.962 96.195  1.00 71.66  ? 236 PRO B N   1 
ATOM   3628 C CA  . PRO B 2 236 ? 149.428 125.166 95.347  1.00 70.97  ? 236 PRO B CA  1 
ATOM   3629 C C   . PRO B 2 236 ? 149.947 124.937 93.941  1.00 79.48  ? 236 PRO B C   1 
ATOM   3630 O O   . PRO B 2 236 ? 149.606 125.716 93.043  1.00 85.24  ? 236 PRO B O   1 
ATOM   3631 C CB  . PRO B 2 236 ? 150.293 126.182 96.104  1.00 67.79  ? 236 PRO B CB  1 
ATOM   3632 C CG  . PRO B 2 236 ? 150.839 125.498 97.285  1.00 71.97  ? 236 PRO B CG  1 
ATOM   3633 C CD  . PRO B 2 236 ? 150.370 124.092 97.348  1.00 74.58  ? 236 PRO B CD  1 
ATOM   3634 N N   . ASN B 2 237 ? 150.757 123.902 93.715  1.00 81.23  ? 237 ASN B N   1 
ATOM   3635 C CA  . ASN B 2 237 ? 151.163 123.575 92.353  1.00 76.37  ? 237 ASN B CA  1 
ATOM   3636 C C   . ASN B 2 237 ? 149.976 123.142 91.507  1.00 78.07  ? 237 ASN B C   1 
ATOM   3637 O O   . ASN B 2 237 ? 149.976 123.339 90.288  1.00 83.09  ? 237 ASN B O   1 
ATOM   3638 C CB  . ASN B 2 237 ? 152.224 122.476 92.371  1.00 77.27  ? 237 ASN B CB  1 
ATOM   3639 C CG  . ASN B 2 237 ? 152.948 122.344 91.050  1.00 83.01  ? 237 ASN B CG  1 
ATOM   3640 O OD1 . ASN B 2 237 ? 152.762 123.153 90.142  1.00 89.18  ? 237 ASN B OD1 1 
ATOM   3641 N ND2 . ASN B 2 237 ? 153.775 121.313 90.931  1.00 81.21  ? 237 ASN B ND2 1 
ATOM   3642 N N   . GLY B 2 238 ? 148.957 122.558 92.131  1.00 77.32  ? 238 GLY B N   1 
ATOM   3643 C CA  . GLY B 2 238 ? 147.799 122.071 91.417  1.00 77.55  ? 238 GLY B CA  1 
ATOM   3644 C C   . GLY B 2 238 ? 147.886 120.638 90.944  1.00 83.01  ? 238 GLY B C   1 
ATOM   3645 O O   . GLY B 2 238 ? 146.902 120.124 90.400  1.00 86.18  ? 238 GLY B O   1 
ATOM   3646 N N   . ASN B 2 239 ? 149.026 119.974 91.130  1.00 87.01  ? 239 ASN B N   1 
ATOM   3647 C CA  . ASN B 2 239 ? 149.196 118.583 90.733  1.00 86.56  ? 239 ASN B CA  1 
ATOM   3648 C C   . ASN B 2 239 ? 149.464 117.676 91.930  1.00 89.94  ? 239 ASN B C   1 
ATOM   3649 O O   . ASN B 2 239 ? 150.156 116.664 91.808  1.00 93.51  ? 239 ASN B O   1 
ATOM   3650 C CB  . ASN B 2 239 ? 150.314 118.453 89.701  1.00 84.62  ? 239 ASN B CB  1 
ATOM   3651 C CG  . ASN B 2 239 ? 151.638 118.978 90.207  1.00 91.47  ? 239 ASN B CG  1 
ATOM   3652 O OD1 . ASN B 2 239 ? 151.736 119.474 91.327  1.00 95.43  ? 239 ASN B OD1 1 
ATOM   3653 N ND2 . ASN B 2 239 ? 152.670 118.869 89.380  1.00 91.16  ? 239 ASN B ND2 1 
ATOM   3654 N N   . ALA B 2 240 ? 148.929 118.035 93.094  1.00 87.36  ? 240 ALA B N   1 
ATOM   3655 C CA  . ALA B 2 240 ? 149.031 117.204 94.284  1.00 82.34  ? 240 ALA B CA  1 
ATOM   3656 C C   . ALA B 2 240 ? 147.958 117.642 95.265  1.00 86.48  ? 240 ALA B C   1 
ATOM   3657 O O   . ALA B 2 240 ? 147.405 118.738 95.157  1.00 98.76  ? 240 ALA B O   1 
ATOM   3658 C CB  . ALA B 2 240 ? 150.419 117.294 94.922  1.00 87.35  ? 240 ALA B CB  1 
ATOM   3659 N N   . PHE B 2 241 ? 147.673 116.773 96.230  1.00 75.41  ? 241 PHE B N   1 
ATOM   3660 C CA  . PHE B 2 241 ? 146.678 117.079 97.245  1.00 80.30  ? 241 PHE B CA  1 
ATOM   3661 C C   . PHE B 2 241 ? 146.900 116.186 98.455  1.00 84.81  ? 241 PHE B C   1 
ATOM   3662 O O   . PHE B 2 241 ? 147.341 115.041 98.330  1.00 94.29  ? 241 PHE B O   1 
ATOM   3663 C CB  . PHE B 2 241 ? 145.257 116.904 96.708  1.00 81.86  ? 241 PHE B CB  1 
ATOM   3664 C CG  . PHE B 2 241 ? 144.872 115.477 96.472  1.00 80.27  ? 241 PHE B CG  1 
ATOM   3665 C CD1 . PHE B 2 241 ? 145.286 114.814 95.334  1.00 82.32  ? 241 PHE B CD1 1 
ATOM   3666 C CD2 . PHE B 2 241 ? 144.098 114.799 97.388  1.00 82.41  ? 241 PHE B CD2 1 
ATOM   3667 C CE1 . PHE B 2 241 ? 144.931 113.502 95.119  1.00 81.42  ? 241 PHE B CE1 1 
ATOM   3668 C CE2 . PHE B 2 241 ? 143.742 113.489 97.179  1.00 84.34  ? 241 PHE B CE2 1 
ATOM   3669 C CZ  . PHE B 2 241 ? 144.159 112.840 96.044  1.00 84.38  ? 241 PHE B CZ  1 
ATOM   3670 N N   . ALA B 2 242 ? 146.551 116.713 99.623  1.00 78.47  ? 242 ALA B N   1 
ATOM   3671 C CA  . ALA B 2 242 ? 146.716 116.016 100.887 1.00 74.98  ? 242 ALA B CA  1 
ATOM   3672 C C   . ALA B 2 242 ? 145.363 115.676 101.495 1.00 76.57  ? 242 ALA B C   1 
ATOM   3673 O O   . ALA B 2 242 ? 144.382 116.402 101.315 1.00 89.13  ? 242 ALA B O   1 
ATOM   3674 C CB  . ALA B 2 242 ? 147.517 116.858 101.874 1.00 78.07  ? 242 ALA B CB  1 
ATOM   3675 N N   . THR B 2 243 ? 145.326 114.564 102.224 1.00 73.99  ? 243 THR B N   1 
ATOM   3676 C CA  . THR B 2 243 ? 144.111 114.063 102.846 1.00 75.62  ? 243 THR B CA  1 
ATOM   3677 C C   . THR B 2 243 ? 144.353 113.846 104.329 1.00 79.02  ? 243 THR B C   1 
ATOM   3678 O O   . THR B 2 243 ? 145.374 113.273 104.718 1.00 86.41  ? 243 THR B O   1 
ATOM   3679 C CB  . THR B 2 243 ? 143.670 112.733 102.239 1.00 86.47  ? 243 THR B CB  1 
ATOM   3680 O OG1 . THR B 2 243 ? 144.746 111.792 102.334 1.00 94.26  ? 243 THR B OG1 1 
ATOM   3681 C CG2 . THR B 2 243 ? 143.312 112.911 100.782 1.00 82.89  ? 243 THR B CG2 1 
ATOM   3682 N N   . GLY B 2 244 ? 143.401 114.282 105.144 1.00 86.53  ? 244 GLY B N   1 
ATOM   3683 C CA  . GLY B 2 244 ? 143.374 113.969 106.565 1.00 90.10  ? 244 GLY B CA  1 
ATOM   3684 C C   . GLY B 2 244 ? 142.192 113.061 106.856 1.00 93.73  ? 244 GLY B C   1 
ATOM   3685 O O   . GLY B 2 244 ? 141.109 113.244 106.294 1.00 97.34  ? 244 GLY B O   1 
ATOM   3686 N N   . SER B 2 245 ? 142.403 112.082 107.730 1.00 88.60  ? 245 SER B N   1 
ATOM   3687 C CA  . SER B 2 245 ? 141.395 111.071 108.005 1.00 85.68  ? 245 SER B CA  1 
ATOM   3688 C C   . SER B 2 245 ? 141.193 110.922 109.505 1.00 87.35  ? 245 SER B C   1 
ATOM   3689 O O   . SER B 2 245 ? 141.898 111.527 110.316 1.00 96.24  ? 245 SER B O   1 
ATOM   3690 C CB  . SER B 2 245 ? 141.781 109.722 107.389 1.00 90.00  ? 245 SER B CB  1 
ATOM   3691 O OG  . SER B 2 245 ? 143.016 109.264 107.908 1.00 95.84  ? 245 SER B OG  1 
ATOM   3692 N N   . ASP B 2 246 ? 140.202 110.103 109.871 1.00 85.54  ? 246 ASP B N   1 
ATOM   3693 C CA  . ASP B 2 246 ? 140.017 109.761 111.276 1.00 87.80  ? 246 ASP B CA  1 
ATOM   3694 C C   . ASP B 2 246 ? 141.218 109.003 111.817 1.00 90.66  ? 246 ASP B C   1 
ATOM   3695 O O   . ASP B 2 246 ? 141.591 109.177 112.982 1.00 95.45  ? 246 ASP B O   1 
ATOM   3696 C CB  . ASP B 2 246 ? 138.744 108.941 111.466 1.00 89.28  ? 246 ASP B CB  1 
ATOM   3697 C CG  . ASP B 2 246 ? 137.580 109.782 111.948 1.00 96.40  ? 246 ASP B CG  1 
ATOM   3698 O OD1 . ASP B 2 246 ? 137.770 110.998 112.153 1.00 93.98  ? 246 ASP B OD1 1 
ATOM   3699 O OD2 . ASP B 2 246 ? 136.476 109.227 112.123 1.00 98.25  ? 246 ASP B OD2 1 
ATOM   3700 N N   . ASP B 2 247 ? 141.821 108.146 111.001 1.00 85.83  ? 247 ASP B N   1 
ATOM   3701 C CA  . ASP B 2 247 ? 143.135 107.625 111.331 1.00 85.04  ? 247 ASP B CA  1 
ATOM   3702 C C   . ASP B 2 247 ? 144.107 108.797 111.364 1.00 91.70  ? 247 ASP B C   1 
ATOM   3703 O O   . ASP B 2 247 ? 144.091 109.661 110.484 1.00 99.23  ? 247 ASP B O   1 
ATOM   3704 C CB  . ASP B 2 247 ? 143.551 106.575 110.295 1.00 87.59  ? 247 ASP B CB  1 
ATOM   3705 C CG  . ASP B 2 247 ? 145.061 106.398 110.175 1.00 96.61  ? 247 ASP B CG  1 
ATOM   3706 O OD1 . ASP B 2 247 ? 145.817 106.725 111.116 1.00 98.81  ? 247 ASP B OD1 1 
ATOM   3707 O OD2 . ASP B 2 247 ? 145.491 105.827 109.152 1.00 96.94  ? 247 ASP B OD2 1 
ATOM   3708 N N   . ALA B 2 248 ? 144.964 108.826 112.383 1.00 93.07  ? 248 ALA B N   1 
ATOM   3709 C CA  . ALA B 2 248 ? 145.830 109.979 112.625 1.00 94.53  ? 248 ALA B CA  1 
ATOM   3710 C C   . ALA B 2 248 ? 146.983 110.015 111.620 1.00 96.64  ? 248 ALA B C   1 
ATOM   3711 O O   . ALA B 2 248 ? 148.163 109.961 111.965 1.00 102.83 ? 248 ALA B O   1 
ATOM   3712 C CB  . ALA B 2 248 ? 146.347 109.953 114.057 1.00 98.10  ? 248 ALA B CB  1 
ATOM   3713 N N   . THR B 2 249 ? 146.612 110.113 110.346 1.00 83.28  ? 249 THR B N   1 
ATOM   3714 C CA  . THR B 2 249 ? 147.567 110.164 109.251 1.00 84.78  ? 249 THR B CA  1 
ATOM   3715 C C   . THR B 2 249 ? 147.114 111.201 108.239 1.00 90.81  ? 249 THR B C   1 
ATOM   3716 O O   . THR B 2 249 ? 145.916 111.337 107.975 1.00 90.95  ? 249 THR B O   1 
ATOM   3717 C CB  . THR B 2 249 ? 147.706 108.806 108.551 1.00 89.58  ? 249 THR B CB  1 
ATOM   3718 O OG1 . THR B 2 249 ? 146.412 108.344 108.146 1.00 93.56  ? 249 THR B OG1 1 
ATOM   3719 C CG2 . THR B 2 249 ? 148.344 107.781 109.471 1.00 88.98  ? 249 THR B CG2 1 
ATOM   3720 N N   . CYS B 2 250 ? 148.072 111.930 107.674 1.00 94.73  ? 250 CYS B N   1 
ATOM   3721 C CA  . CYS B 2 250 ? 147.816 112.815 106.545 1.00 88.95  ? 250 CYS B CA  1 
ATOM   3722 C C   . CYS B 2 250 ? 148.624 112.307 105.362 1.00 90.55  ? 250 CYS B C   1 
ATOM   3723 O O   . CYS B 2 250 ? 149.849 112.220 105.440 1.00 96.56  ? 250 CYS B O   1 
ATOM   3724 C CB  . CYS B 2 250 ? 148.180 114.262 106.877 1.00 89.06  ? 250 CYS B CB  1 
ATOM   3725 S SG  . CYS B 2 250 ? 147.158 115.005 108.165 1.00 101.66 ? 250 CYS B SG  1 
ATOM   3726 N N   . ARG B 2 251 ? 147.947 111.973 104.273 1.00 78.29  ? 251 ARG B N   1 
ATOM   3727 C CA  . ARG B 2 251 ? 148.592 111.321 103.141 1.00 81.89  ? 251 ARG B CA  1 
ATOM   3728 C C   . ARG B 2 251 ? 148.567 112.238 101.929 1.00 84.50  ? 251 ARG B C   1 
ATOM   3729 O O   . ARG B 2 251 ? 147.530 112.829 101.618 1.00 91.70  ? 251 ARG B O   1 
ATOM   3730 C CB  . ARG B 2 251 ? 147.914 109.987 102.826 1.00 86.12  ? 251 ARG B CB  1 
ATOM   3731 C CG  . ARG B 2 251 ? 148.035 108.974 103.953 1.00 89.84  ? 251 ARG B CG  1 
ATOM   3732 C CD  . ARG B 2 251 ? 147.424 107.638 103.581 1.00 88.09  ? 251 ARG B CD  1 
ATOM   3733 N NE  . ARG B 2 251 ? 147.472 106.699 104.695 1.00 85.86  ? 251 ARG B NE  1 
ATOM   3734 C CZ  . ARG B 2 251 ? 148.416 105.783 104.857 1.00 88.29  ? 251 ARG B CZ  1 
ATOM   3735 N NH1 . ARG B 2 251 ? 149.409 105.655 103.993 1.00 87.44  ? 251 ARG B NH1 1 
ATOM   3736 N NH2 . ARG B 2 251 ? 148.363 104.977 105.912 1.00 87.97  ? 251 ARG B NH2 1 
ATOM   3737 N N   . LEU B 2 252 ? 149.701 112.350 101.244 1.00 78.75  ? 252 LEU B N   1 
ATOM   3738 C CA  . LEU B 2 252 ? 149.837 113.235 100.094 1.00 71.05  ? 252 LEU B CA  1 
ATOM   3739 C C   . LEU B 2 252 ? 149.868 112.409 98.815  1.00 81.17  ? 252 LEU B C   1 
ATOM   3740 O O   . LEU B 2 252 ? 150.808 111.638 98.594  1.00 90.93  ? 252 LEU B O   1 
ATOM   3741 C CB  . LEU B 2 252 ? 151.098 114.088 100.211 1.00 71.22  ? 252 LEU B CB  1 
ATOM   3742 C CG  . LEU B 2 252 ? 151.481 114.910 98.983  1.00 77.96  ? 252 LEU B CG  1 
ATOM   3743 C CD1 . LEU B 2 252 ? 150.481 116.029 98.762  1.00 81.33  ? 252 LEU B CD1 1 
ATOM   3744 C CD2 . LEU B 2 252 ? 152.883 115.466 99.131  1.00 79.73  ? 252 LEU B CD2 1 
ATOM   3745 N N   . PHE B 2 253 ? 148.848 112.575 97.977  1.00 82.63  ? 253 PHE B N   1 
ATOM   3746 C CA  . PHE B 2 253 ? 148.778 111.937 96.669  1.00 81.91  ? 253 PHE B CA  1 
ATOM   3747 C C   . PHE B 2 253 ? 148.963 112.995 95.595  1.00 88.77  ? 253 PHE B C   1 
ATOM   3748 O O   . PHE B 2 253 ? 148.309 114.040 95.637  1.00 94.78  ? 253 PHE B O   1 
ATOM   3749 C CB  . PHE B 2 253 ? 147.433 111.241 96.444  1.00 84.22  ? 253 PHE B CB  1 
ATOM   3750 C CG  . PHE B 2 253 ? 146.885 110.535 97.647  1.00 84.59  ? 253 PHE B CG  1 
ATOM   3751 C CD1 . PHE B 2 253 ? 146.071 111.195 98.546  1.00 81.47  ? 253 PHE B CD1 1 
ATOM   3752 C CD2 . PHE B 2 253 ? 147.156 109.198 97.857  1.00 91.28  ? 253 PHE B CD2 1 
ATOM   3753 C CE1 . PHE B 2 253 ? 145.560 110.539 99.641  1.00 82.76  ? 253 PHE B CE1 1 
ATOM   3754 C CE2 . PHE B 2 253 ? 146.644 108.540 98.951  1.00 92.33  ? 253 PHE B CE2 1 
ATOM   3755 C CZ  . PHE B 2 253 ? 145.846 109.211 99.844  1.00 88.63  ? 253 PHE B CZ  1 
ATOM   3756 N N   . ASP B 2 254 ? 149.828 112.727 94.627  1.00 93.84  ? 254 ASP B N   1 
ATOM   3757 C CA  . ASP B 2 254 ? 149.931 113.619 93.483  1.00 98.62  ? 254 ASP B CA  1 
ATOM   3758 C C   . ASP B 2 254 ? 149.192 113.031 92.284  1.00 97.31  ? 254 ASP B C   1 
ATOM   3759 O O   . ASP B 2 254 ? 148.997 111.819 92.173  1.00 97.96  ? 254 ASP B O   1 
ATOM   3760 C CB  . ASP B 2 254 ? 151.402 113.955 93.178  1.00 97.88  ? 254 ASP B CB  1 
ATOM   3761 C CG  . ASP B 2 254 ? 152.188 112.815 92.543  1.00 98.27  ? 254 ASP B CG  1 
ATOM   3762 O OD1 . ASP B 2 254 ? 151.627 111.910 91.907  1.00 96.66  ? 254 ASP B OD1 1 
ATOM   3763 O OD2 . ASP B 2 254 ? 153.429 112.856 92.660  1.00 104.76 ? 254 ASP B OD2 1 
ATOM   3764 N N   . LEU B 2 255 ? 148.734 113.921 91.405  1.00 88.30  ? 255 LEU B N   1 
ATOM   3765 C CA  . LEU B 2 255 ? 147.797 113.520 90.364  1.00 80.11  ? 255 LEU B CA  1 
ATOM   3766 C C   . LEU B 2 255 ? 148.472 112.765 89.228  1.00 81.45  ? 255 LEU B C   1 
ATOM   3767 O O   . LEU B 2 255 ? 147.840 111.910 88.599  1.00 90.69  ? 255 LEU B O   1 
ATOM   3768 C CB  . LEU B 2 255 ? 147.071 114.749 89.818  1.00 82.99  ? 255 LEU B CB  1 
ATOM   3769 C CG  . LEU B 2 255 ? 146.389 115.622 90.871  1.00 87.57  ? 255 LEU B CG  1 
ATOM   3770 C CD1 . LEU B 2 255 ? 145.564 116.722 90.217  1.00 87.47  ? 255 LEU B CD1 1 
ATOM   3771 C CD2 . LEU B 2 255 ? 145.536 114.776 91.798  1.00 88.89  ? 255 LEU B CD2 1 
ATOM   3772 N N   . ARG B 2 256 ? 149.740 113.062 88.948  1.00 87.76  ? 256 ARG B N   1 
ATOM   3773 C CA  . ARG B 2 256 ? 150.415 112.414 87.829  1.00 92.05  ? 256 ARG B CA  1 
ATOM   3774 C C   . ARG B 2 256 ? 150.793 110.975 88.161  1.00 94.65  ? 256 ARG B C   1 
ATOM   3775 O O   . ARG B 2 256 ? 150.793 110.109 87.279  1.00 95.17  ? 256 ARG B O   1 
ATOM   3776 C CB  . ARG B 2 256 ? 151.643 113.228 87.428  1.00 94.88  ? 256 ARG B CB  1 
ATOM   3777 C CG  . ARG B 2 256 ? 151.302 114.503 86.673  1.00 93.75  ? 256 ARG B CG  1 
ATOM   3778 C CD  . ARG B 2 256 ? 152.094 115.688 87.195  1.00 92.11  ? 256 ARG B CD  1 
ATOM   3779 N NE  . ARG B 2 256 ? 153.496 115.625 86.804  1.00 93.76  ? 256 ARG B NE  1 
ATOM   3780 C CZ  . ARG B 2 256 ? 154.123 116.570 86.119  1.00 97.12  ? 256 ARG B CZ  1 
ATOM   3781 N NH1 . ARG B 2 256 ? 153.501 117.671 85.731  1.00 97.75  ? 256 ARG B NH1 1 
ATOM   3782 N NH2 . ARG B 2 256 ? 155.407 116.406 85.814  1.00 96.70  ? 256 ARG B NH2 1 
ATOM   3783 N N   . ALA B 2 257 ? 151.125 110.700 89.420  1.00 94.87  ? 257 ALA B N   1 
ATOM   3784 C CA  . ALA B 2 257 ? 151.410 109.348 89.893  1.00 94.44  ? 257 ALA B CA  1 
ATOM   3785 C C   . ALA B 2 257 ? 150.414 109.023 90.999  1.00 98.82  ? 257 ALA B C   1 
ATOM   3786 O O   . ALA B 2 257 ? 150.521 109.549 92.110  1.00 108.52 ? 257 ALA B O   1 
ATOM   3787 C CB  . ALA B 2 257 ? 152.848 109.232 90.388  1.00 97.25  ? 257 ALA B CB  1 
ATOM   3788 N N   . ASP B 2 258 ? 149.471 108.126 90.704  1.00 88.83  ? 258 ASP B N   1 
ATOM   3789 C CA  . ASP B 2 258 ? 148.297 107.973 91.559  1.00 91.67  ? 258 ASP B CA  1 
ATOM   3790 C C   . ASP B 2 258 ? 148.670 107.583 92.986  1.00 93.94  ? 258 ASP B C   1 
ATOM   3791 O O   . ASP B 2 258 ? 148.096 108.110 93.946  1.00 97.95  ? 258 ASP B O   1 
ATOM   3792 C CB  . ASP B 2 258 ? 147.344 106.943 90.959  1.00 95.81  ? 258 ASP B CB  1 
ATOM   3793 C CG  . ASP B 2 258 ? 147.141 107.138 89.474  1.00 98.28  ? 258 ASP B CG  1 
ATOM   3794 O OD1 . ASP B 2 258 ? 147.512 108.214 88.962  1.00 96.85  ? 258 ASP B OD1 1 
ATOM   3795 O OD2 . ASP B 2 258 ? 146.599 106.222 88.823  1.00 95.91  ? 258 ASP B OD2 1 
ATOM   3796 N N   . GLN B 2 259 ? 149.619 106.669 93.152  1.00 89.82  ? 259 GLN B N   1 
ATOM   3797 C CA  . GLN B 2 259 ? 149.924 106.170 94.485  1.00 90.09  ? 259 GLN B CA  1 
ATOM   3798 C C   . GLN B 2 259 ? 150.477 107.280 95.371  1.00 87.40  ? 259 GLN B C   1 
ATOM   3799 O O   . GLN B 2 259 ? 151.094 108.237 94.898  1.00 88.80  ? 259 GLN B O   1 
ATOM   3800 C CB  . GLN B 2 259 ? 150.909 104.998 94.424  1.00 93.34  ? 259 GLN B CB  1 
ATOM   3801 C CG  . GLN B 2 259 ? 152.339 105.288 93.948  1.00 90.65  ? 259 GLN B CG  1 
ATOM   3802 C CD  . GLN B 2 259 ? 152.443 105.796 92.517  1.00 95.47  ? 259 GLN B CD  1 
ATOM   3803 O OE1 . GLN B 2 259 ? 151.516 106.391 91.972  1.00 96.08  ? 259 GLN B OE1 1 
ATOM   3804 N NE2 . GLN B 2 259 ? 153.575 105.517 91.887  1.00 96.27  ? 259 GLN B NE2 1 
ATOM   3805 N N   . GLU B 2 260 ? 150.231 107.142 96.672  1.00 92.72  ? 260 GLU B N   1 
ATOM   3806 C CA  . GLU B 2 260 ? 150.577 108.182 97.629  1.00 90.65  ? 260 GLU B CA  1 
ATOM   3807 C C   . GLU B 2 260 ? 152.082 108.401 97.680  1.00 95.17  ? 260 GLU B C   1 
ATOM   3808 O O   . GLU B 2 260 ? 152.877 107.500 97.404  1.00 102.90 ? 260 GLU B O   1 
ATOM   3809 C CB  . GLU B 2 260 ? 150.062 107.815 99.018  1.00 90.98  ? 260 GLU B CB  1 
ATOM   3810 C CG  . GLU B 2 260 ? 150.604 106.503 99.546  1.00 102.00 ? 260 GLU B CG  1 
ATOM   3811 C CD  . GLU B 2 260 ? 150.392 106.346 101.036 1.00 103.96 ? 260 GLU B CD  1 
ATOM   3812 O OE1 . GLU B 2 260 ? 149.880 107.294 101.664 1.00 101.31 ? 260 GLU B OE1 1 
ATOM   3813 O OE2 . GLU B 2 260 ? 150.735 105.275 101.579 1.00 103.54 ? 260 GLU B OE2 1 
ATOM   3814 N N   . LEU B 2 261 ? 152.470 109.623 98.038  1.00 83.25  ? 261 LEU B N   1 
ATOM   3815 C CA  . LEU B 2 261 ? 153.879 109.989 98.118  1.00 85.27  ? 261 LEU B CA  1 
ATOM   3816 C C   . LEU B 2 261 ? 154.420 109.796 99.531  1.00 85.72  ? 261 LEU B C   1 
ATOM   3817 O O   . LEU B 2 261 ? 155.375 109.041 99.740  1.00 84.56  ? 261 LEU B O   1 
ATOM   3818 C CB  . LEU B 2 261 ? 154.069 111.437 97.656  1.00 87.14  ? 261 LEU B CB  1 
ATOM   3819 C CG  . LEU B 2 261 ? 154.432 111.633 96.185  1.00 84.77  ? 261 LEU B CG  1 
ATOM   3820 C CD1 . LEU B 2 261 ? 155.805 111.062 95.904  1.00 87.96  ? 261 LEU B CD1 1 
ATOM   3821 C CD2 . LEU B 2 261 ? 153.396 110.996 95.281  1.00 84.20  ? 261 LEU B CD2 1 
ATOM   3822 N N   . MET B 2 262 ? 153.823 110.474 100.508 1.00 96.79  ? 262 MET B N   1 
ATOM   3823 C CA  . MET B 2 262 ? 154.202 110.318 101.903 1.00 97.00  ? 262 MET B CA  1 
ATOM   3824 C C   . MET B 2 262 ? 152.960 110.290 102.776 1.00 98.50  ? 262 MET B C   1 
ATOM   3825 O O   . MET B 2 262 ? 151.878 110.738 102.384 1.00 102.47 ? 262 MET B O   1 
ATOM   3826 C CB  . MET B 2 262 ? 155.131 111.437 102.395 1.00 96.25  ? 262 MET B CB  1 
ATOM   3827 C CG  . MET B 2 262 ? 156.222 111.828 101.433 1.00 103.35 ? 262 MET B CG  1 
ATOM   3828 S SD  . MET B 2 262 ? 157.703 110.828 101.664 1.00 123.49 ? 262 MET B SD  1 
ATOM   3829 C CE  . MET B 2 262 ? 157.711 110.638 103.445 1.00 103.00 ? 262 MET B CE  1 
ATOM   3830 N N   . THR B 2 263 ? 153.136 109.734 103.969 1.00 86.07  ? 263 THR B N   1 
ATOM   3831 C CA  . THR B 2 263 ? 152.143 109.792 105.027 1.00 85.17  ? 263 THR B CA  1 
ATOM   3832 C C   . THR B 2 263 ? 152.785 110.380 106.275 1.00 87.79  ? 263 THR B C   1 
ATOM   3833 O O   . THR B 2 263 ? 153.913 110.030 106.635 1.00 90.42  ? 263 THR B O   1 
ATOM   3834 C CB  . THR B 2 263 ? 151.543 108.408 105.316 1.00 90.56  ? 263 THR B CB  1 
ATOM   3835 O OG1 . THR B 2 263 ? 150.491 108.532 106.281 1.00 92.79  ? 263 THR B OG1 1 
ATOM   3836 C CG2 . THR B 2 263 ? 152.598 107.433 105.823 1.00 91.82  ? 263 THR B CG2 1 
ATOM   3837 N N   . TYR B 2 264 ? 152.074 111.303 106.908 1.00 91.06  ? 264 TYR B N   1 
ATOM   3838 C CA  . TYR B 2 264 ? 152.528 111.981 108.110 1.00 94.80  ? 264 TYR B CA  1 
ATOM   3839 C C   . TYR B 2 264 ? 151.739 111.428 109.285 1.00 97.18  ? 264 TYR B C   1 
ATOM   3840 O O   . TYR B 2 264 ? 150.503 111.498 109.297 1.00 95.05  ? 264 TYR B O   1 
ATOM   3841 C CB  . TYR B 2 264 ? 152.344 113.495 107.998 1.00 96.04  ? 264 TYR B CB  1 
ATOM   3842 C CG  . TYR B 2 264 ? 152.608 114.057 106.620 1.00 95.98  ? 264 TYR B CG  1 
ATOM   3843 C CD1 . TYR B 2 264 ? 153.886 114.073 106.091 1.00 94.61  ? 264 TYR B CD1 1 
ATOM   3844 C CD2 . TYR B 2 264 ? 151.583 114.593 105.860 1.00 93.45  ? 264 TYR B CD2 1 
ATOM   3845 C CE1 . TYR B 2 264 ? 154.132 114.587 104.836 1.00 93.35  ? 264 TYR B CE1 1 
ATOM   3846 C CE2 . TYR B 2 264 ? 151.819 115.107 104.607 1.00 89.11  ? 264 TYR B CE2 1 
ATOM   3847 C CZ  . TYR B 2 264 ? 153.095 115.105 104.100 1.00 90.68  ? 264 TYR B CZ  1 
ATOM   3848 O OH  . TYR B 2 264 ? 153.335 115.621 102.850 1.00 95.87  ? 264 TYR B OH  1 
ATOM   3849 N N   . SER B 2 265 ? 152.455 110.872 110.258 1.00 96.82  ? 265 SER B N   1 
ATOM   3850 C CA  . SER B 2 265 ? 151.842 110.283 111.435 1.00 89.94  ? 265 SER B CA  1 
ATOM   3851 C C   . SER B 2 265 ? 152.877 110.232 112.545 1.00 92.86  ? 265 SER B C   1 
ATOM   3852 O O   . SER B 2 265 ? 154.081 110.348 112.305 1.00 94.39  ? 265 SER B O   1 
ATOM   3853 C CB  . SER B 2 265 ? 151.300 108.881 111.148 1.00 91.80  ? 265 SER B CB  1 
ATOM   3854 O OG  . SER B 2 265 ? 152.350 107.991 110.814 1.00 95.79  ? 265 SER B OG  1 
ATOM   3855 N N   . HIS B 2 266 ? 152.385 110.052 113.766 1.00 105.11 ? 266 HIS B N   1 
ATOM   3856 C CA  . HIS B 2 266 ? 153.238 109.933 114.935 1.00 104.09 ? 266 HIS B CA  1 
ATOM   3857 C C   . HIS B 2 266 ? 152.591 108.957 115.903 1.00 105.46 ? 266 HIS B C   1 
ATOM   3858 O O   . HIS B 2 266 ? 151.385 108.705 115.848 1.00 107.32 ? 266 HIS B O   1 
ATOM   3859 C CB  . HIS B 2 266 ? 153.467 111.290 115.605 1.00 102.84 ? 266 HIS B CB  1 
ATOM   3860 C CG  . HIS B 2 266 ? 154.846 111.466 116.157 1.00 104.75 ? 266 HIS B CG  1 
ATOM   3861 N ND1 . HIS B 2 266 ? 155.378 112.703 116.449 1.00 105.62 ? 266 HIS B ND1 1 
ATOM   3862 C CD2 . HIS B 2 266 ? 155.802 110.561 116.472 1.00 105.65 ? 266 HIS B CD2 1 
ATOM   3863 C CE1 . HIS B 2 266 ? 156.603 112.553 116.919 1.00 106.05 ? 266 HIS B CE1 1 
ATOM   3864 N NE2 . HIS B 2 266 ? 156.885 111.263 116.943 1.00 108.96 ? 266 HIS B NE2 1 
ATOM   3865 N N   . ASP B 2 267 ? 153.410 108.399 116.792 1.00 101.55 ? 267 ASP B N   1 
ATOM   3866 C CA  . ASP B 2 267 ? 152.874 107.477 117.784 1.00 102.22 ? 267 ASP B CA  1 
ATOM   3867 C C   . ASP B 2 267 ? 152.027 108.202 118.820 1.00 100.68 ? 267 ASP B C   1 
ATOM   3868 O O   . ASP B 2 267 ? 151.143 107.593 119.432 1.00 103.38 ? 267 ASP B O   1 
ATOM   3869 C CB  . ASP B 2 267 ? 154.013 106.719 118.461 1.00 105.62 ? 267 ASP B CB  1 
ATOM   3870 C CG  . ASP B 2 267 ? 154.967 106.097 117.463 1.00 106.68 ? 267 ASP B CG  1 
ATOM   3871 O OD1 . ASP B 2 267 ? 154.760 106.287 116.246 1.00 106.47 ? 267 ASP B OD1 1 
ATOM   3872 O OD2 . ASP B 2 267 ? 155.924 105.419 117.894 1.00 106.83 ? 267 ASP B OD2 1 
ATOM   3873 N N   . ASN B 2 268 ? 152.277 109.496 119.029 1.00 103.36 ? 268 ASN B N   1 
ATOM   3874 C CA  . ASN B 2 268 ? 151.572 110.227 120.076 1.00 108.04 ? 268 ASN B CA  1 
ATOM   3875 C C   . ASN B 2 268 ? 150.121 110.495 119.695 1.00 111.65 ? 268 ASN B C   1 
ATOM   3876 O O   . ASN B 2 268 ? 149.211 110.290 120.507 1.00 113.80 ? 268 ASN B O   1 
ATOM   3877 C CB  . ASN B 2 268 ? 152.299 111.536 120.380 1.00 107.66 ? 268 ASN B CB  1 
ATOM   3878 C CG  . ASN B 2 268 ? 153.799 111.415 120.230 1.00 111.63 ? 268 ASN B CG  1 
ATOM   3879 O OD1 . ASN B 2 268 ? 154.315 111.273 119.123 1.00 113.67 ? 268 ASN B OD1 1 
ATOM   3880 N ND2 . ASN B 2 268 ? 154.511 111.469 121.350 1.00 112.59 ? 268 ASN B ND2 1 
ATOM   3881 N N   . ILE B 2 269 ? 149.879 110.954 118.470 1.00 98.19  ? 269 ILE B N   1 
ATOM   3882 C CA  . ILE B 2 269 ? 148.546 111.392 118.071 1.00 94.60  ? 269 ILE B CA  1 
ATOM   3883 C C   . ILE B 2 269 ? 147.723 110.198 117.602 1.00 91.15  ? 269 ILE B C   1 
ATOM   3884 O O   . ILE B 2 269 ? 148.168 109.401 116.769 1.00 94.02  ? 269 ILE B O   1 
ATOM   3885 C CB  . ILE B 2 269 ? 148.617 112.514 117.015 1.00 93.44  ? 269 ILE B CB  1 
ATOM   3886 C CG1 . ILE B 2 269 ? 149.319 112.096 115.711 1.00 92.14  ? 269 ILE B CG1 1 
ATOM   3887 C CG2 . ILE B 2 269 ? 149.324 113.730 117.589 1.00 96.30  ? 269 ILE B CG2 1 
ATOM   3888 C CD1 . ILE B 2 269 ? 149.245 113.056 114.565 1.00 94.58  ? 269 ILE B CD1 1 
ATOM   3889 N N   . ILE B 2 270 ? 146.544 110.036 118.195 1.00 82.52  ? 270 ILE B N   1 
ATOM   3890 C CA  . ILE B 2 270 ? 145.652 108.926 117.879 1.00 86.46  ? 270 ILE B CA  1 
ATOM   3891 C C   . ILE B 2 270 ? 144.331 109.388 117.288 1.00 92.16  ? 270 ILE B C   1 
ATOM   3892 O O   . ILE B 2 270 ? 143.613 108.566 116.698 1.00 97.40  ? 270 ILE B O   1 
ATOM   3893 C CB  . ILE B 2 270 ? 145.382 108.038 119.118 1.00 89.15  ? 270 ILE B CB  1 
ATOM   3894 C CG1 . ILE B 2 270 ? 146.598 107.919 120.045 1.00 91.45  ? 270 ILE B CG1 1 
ATOM   3895 C CG2 . ILE B 2 270 ? 144.952 106.640 118.695 1.00 90.69  ? 270 ILE B CG2 1 
ATOM   3896 C CD1 . ILE B 2 270 ? 147.887 107.473 119.374 1.00 92.08  ? 270 ILE B CD1 1 
ATOM   3897 N N   . CYS B 2 271 ? 143.991 110.666 117.405 1.00 93.65  ? 271 CYS B N   1 
ATOM   3898 C CA  . CYS B 2 271 ? 142.660 111.145 117.063 1.00 93.61  ? 271 CYS B CA  1 
ATOM   3899 C C   . CYS B 2 271 ? 142.531 111.317 115.551 1.00 98.86  ? 271 CYS B C   1 
ATOM   3900 O O   . CYS B 2 271 ? 143.366 110.856 114.770 1.00 102.47 ? 271 CYS B O   1 
ATOM   3901 C CB  . CYS B 2 271 ? 142.373 112.449 117.790 1.00 95.65  ? 271 CYS B CB  1 
ATOM   3902 S SG  . CYS B 2 271 ? 143.407 113.800 117.220 1.00 111.14 ? 271 CYS B SG  1 
ATOM   3903 N N   . GLY B 2 272 ? 141.472 111.995 115.124 1.00 98.49  ? 272 GLY B N   1 
ATOM   3904 C CA  . GLY B 2 272 ? 141.167 112.172 113.712 1.00 98.97  ? 272 GLY B CA  1 
ATOM   3905 C C   . GLY B 2 272 ? 141.438 113.593 113.250 1.00 98.95  ? 272 GLY B C   1 
ATOM   3906 O O   . GLY B 2 272 ? 141.144 114.555 113.965 1.00 101.92 ? 272 GLY B O   1 
ATOM   3907 N N   . ILE B 2 273 ? 141.998 113.711 112.047 1.00 83.35  ? 273 ILE B N   1 
ATOM   3908 C CA  . ILE B 2 273 ? 142.228 115.017 111.444 1.00 74.81  ? 273 ILE B CA  1 
ATOM   3909 C C   . ILE B 2 273 ? 140.901 115.594 110.975 1.00 78.55  ? 273 ILE B C   1 
ATOM   3910 O O   . ILE B 2 273 ? 140.121 114.923 110.288 1.00 86.09  ? 273 ILE B O   1 
ATOM   3911 C CB  . ILE B 2 273 ? 143.225 114.904 110.284 1.00 75.04  ? 273 ILE B CB  1 
ATOM   3912 C CG1 . ILE B 2 273 ? 144.579 114.416 110.794 1.00 78.75  ? 273 ILE B CG1 1 
ATOM   3913 C CG2 . ILE B 2 273 ? 143.377 116.237 109.592 1.00 76.62  ? 273 ILE B CG2 1 
ATOM   3914 C CD1 . ILE B 2 273 ? 144.830 112.951 110.557 1.00 81.74  ? 273 ILE B CD1 1 
ATOM   3915 N N   . THR B 2 274 ? 140.637 116.845 111.344 1.00 78.33  ? 274 THR B N   1 
ATOM   3916 C CA  . THR B 2 274 ? 139.386 117.508 111.003 1.00 82.92  ? 274 THR B CA  1 
ATOM   3917 C C   . THR B 2 274 ? 139.490 118.378 109.759 1.00 83.57  ? 274 THR B C   1 
ATOM   3918 O O   . THR B 2 274 ? 138.550 118.424 108.962 1.00 87.07  ? 274 THR B O   1 
ATOM   3919 C CB  . THR B 2 274 ? 138.906 118.364 112.176 1.00 83.29  ? 274 THR B CB  1 
ATOM   3920 O OG1 . THR B 2 274 ? 139.215 117.703 113.408 1.00 87.61  ? 274 THR B OG1 1 
ATOM   3921 C CG2 . THR B 2 274 ? 137.406 118.586 112.091 1.00 84.50  ? 274 THR B CG2 1 
ATOM   3922 N N   . SER B 2 275 ? 140.609 119.072 109.574 1.00 74.63  ? 275 SER B N   1 
ATOM   3923 C CA  . SER B 2 275 ? 140.795 119.930 108.417 1.00 75.42  ? 275 SER B CA  1 
ATOM   3924 C C   . SER B 2 275 ? 142.273 119.970 108.064 1.00 73.47  ? 275 SER B C   1 
ATOM   3925 O O   . SER B 2 275 ? 143.132 119.797 108.927 1.00 82.06  ? 275 SER B O   1 
ATOM   3926 C CB  . SER B 2 275 ? 140.259 121.338 108.681 1.00 81.13  ? 275 SER B CB  1 
ATOM   3927 O OG  . SER B 2 275 ? 141.190 122.095 109.426 1.00 87.49  ? 275 SER B OG  1 
ATOM   3928 N N   . VAL B 2 276 ? 142.560 120.185 106.783 1.00 73.94  ? 276 VAL B N   1 
ATOM   3929 C CA  . VAL B 2 276 ? 143.926 120.248 106.275 1.00 74.19  ? 276 VAL B CA  1 
ATOM   3930 C C   . VAL B 2 276 ? 144.039 121.441 105.339 1.00 81.88  ? 276 VAL B C   1 
ATOM   3931 O O   . VAL B 2 276 ? 143.131 121.702 104.543 1.00 95.75  ? 276 VAL B O   1 
ATOM   3932 C CB  . VAL B 2 276 ? 144.332 118.951 105.543 1.00 75.90  ? 276 VAL B CB  1 
ATOM   3933 C CG1 . VAL B 2 276 ? 145.727 119.075 104.970 1.00 78.52  ? 276 VAL B CG1 1 
ATOM   3934 C CG2 . VAL B 2 276 ? 144.265 117.767 106.479 1.00 82.51  ? 276 VAL B CG2 1 
ATOM   3935 N N   . SER B 2 277 ? 145.150 122.169 105.436 1.00 75.10  ? 277 SER B N   1 
ATOM   3936 C CA  . SER B 2 277 ? 145.405 123.268 104.520 1.00 72.10  ? 277 SER B CA  1 
ATOM   3937 C C   . SER B 2 277 ? 146.902 123.405 104.301 1.00 70.91  ? 277 SER B C   1 
ATOM   3938 O O   . SER B 2 277 ? 147.687 123.306 105.246 1.00 86.58  ? 277 SER B O   1 
ATOM   3939 C CB  . SER B 2 277 ? 144.826 124.583 105.045 1.00 79.96  ? 277 SER B CB  1 
ATOM   3940 O OG  . SER B 2 277 ? 145.610 125.682 104.621 1.00 86.51  ? 277 SER B OG  1 
ATOM   3941 N N   . PHE B 2 278 ? 147.291 123.633 103.054 1.00 63.32  ? 278 PHE B N   1 
ATOM   3942 C CA  . PHE B 2 278 ? 148.695 123.803 102.732 1.00 66.17  ? 278 PHE B CA  1 
ATOM   3943 C C   . PHE B 2 278 ? 149.121 125.254 102.937 1.00 73.67  ? 278 PHE B C   1 
ATOM   3944 O O   . PHE B 2 278 ? 148.301 126.155 103.125 1.00 79.25  ? 278 PHE B O   1 
ATOM   3945 C CB  . PHE B 2 278 ? 148.971 123.379 101.293 1.00 73.14  ? 278 PHE B CB  1 
ATOM   3946 C CG  . PHE B 2 278 ? 149.577 122.015 101.165 1.00 76.92  ? 278 PHE B CG  1 
ATOM   3947 C CD1 . PHE B 2 278 ? 150.938 121.832 101.313 1.00 80.77  ? 278 PHE B CD1 1 
ATOM   3948 C CD2 . PHE B 2 278 ? 148.788 120.917 100.880 1.00 72.56  ? 278 PHE B CD2 1 
ATOM   3949 C CE1 . PHE B 2 278 ? 151.496 120.580 101.191 1.00 78.81  ? 278 PHE B CE1 1 
ATOM   3950 C CE2 . PHE B 2 278 ? 149.344 119.665 100.756 1.00 76.84  ? 278 PHE B CE2 1 
ATOM   3951 C CZ  . PHE B 2 278 ? 150.699 119.497 100.909 1.00 76.98  ? 278 PHE B CZ  1 
ATOM   3952 N N   . SER B 2 279 ? 150.428 125.471 102.901 1.00 86.35  ? 279 SER B N   1 
ATOM   3953 C CA  . SER B 2 279 ? 150.985 126.811 102.857 1.00 84.54  ? 279 SER B CA  1 
ATOM   3954 C C   . SER B 2 279 ? 151.222 127.222 101.406 1.00 90.60  ? 279 SER B C   1 
ATOM   3955 O O   . SER B 2 279 ? 151.100 126.420 100.479 1.00 95.51  ? 279 SER B O   1 
ATOM   3956 C CB  . SER B 2 279 ? 152.281 126.880 103.659 1.00 85.40  ? 279 SER B CB  1 
ATOM   3957 O OG  . SER B 2 279 ? 152.805 128.194 103.657 1.00 88.66  ? 279 SER B OG  1 
ATOM   3958 N N   . LYS B 2 280 ? 151.561 128.497 101.213 1.00 85.74  ? 280 LYS B N   1 
ATOM   3959 C CA  . LYS B 2 280 ? 151.725 129.011 99.856  1.00 86.24  ? 280 LYS B CA  1 
ATOM   3960 C C   . LYS B 2 280 ? 152.892 128.344 99.141  1.00 86.40  ? 280 LYS B C   1 
ATOM   3961 O O   . LYS B 2 280 ? 152.795 128.029 97.950  1.00 93.13  ? 280 LYS B O   1 
ATOM   3962 C CB  . LYS B 2 280 ? 151.898 130.527 99.883  1.00 87.99  ? 280 LYS B CB  1 
ATOM   3963 C CG  . LYS B 2 280 ? 150.587 131.285 100.019 1.00 90.58  ? 280 LYS B CG  1 
ATOM   3964 C CD  . LYS B 2 280 ? 149.507 130.681 99.128  1.00 92.36  ? 280 LYS B CD  1 
ATOM   3965 C CE  . LYS B 2 280 ? 148.349 130.124 99.944  1.00 91.26  ? 280 LYS B CE  1 
ATOM   3966 N NZ  . LYS B 2 280 ? 147.232 129.657 99.077  1.00 91.22  ? 280 LYS B NZ  1 
ATOM   3967 N N   . SER B 2 281 ? 154.001 128.123 99.840  1.00 77.67  ? 281 SER B N   1 
ATOM   3968 C CA  . SER B 2 281 ? 155.130 127.440 99.227  1.00 86.25  ? 281 SER B CA  1 
ATOM   3969 C C   . SER B 2 281 ? 154.925 125.938 99.127  1.00 89.95  ? 281 SER B C   1 
ATOM   3970 O O   . SER B 2 281 ? 155.710 125.266 98.451  1.00 86.15  ? 281 SER B O   1 
ATOM   3971 C CB  . SER B 2 281 ? 156.410 127.722 100.012 1.00 87.89  ? 281 SER B CB  1 
ATOM   3972 O OG  . SER B 2 281 ? 156.366 127.109 101.288 1.00 93.22  ? 281 SER B OG  1 
ATOM   3973 N N   . GLY B 2 282 ? 153.904 125.397 99.784  1.00 94.79  ? 282 GLY B N   1 
ATOM   3974 C CA  . GLY B 2 282 ? 153.688 123.970 99.805  1.00 92.69  ? 282 GLY B CA  1 
ATOM   3975 C C   . GLY B 2 282 ? 154.619 123.207 100.716 1.00 92.22  ? 282 GLY B C   1 
ATOM   3976 O O   . GLY B 2 282 ? 154.491 121.981 100.818 1.00 98.04  ? 282 GLY B O   1 
ATOM   3977 N N   . ARG B 2 283 ? 155.549 123.889 101.381 1.00 85.11  ? 283 ARG B N   1 
ATOM   3978 C CA  . ARG B 2 283 ? 156.474 123.217 102.281 1.00 82.44  ? 283 ARG B CA  1 
ATOM   3979 C C   . ARG B 2 283 ? 155.807 122.815 103.586 1.00 83.43  ? 283 ARG B C   1 
ATOM   3980 O O   . ARG B 2 283 ? 156.214 121.825 104.204 1.00 95.84  ? 283 ARG B O   1 
ATOM   3981 C CB  . ARG B 2 283 ? 157.676 124.118 102.560 1.00 87.82  ? 283 ARG B CB  1 
ATOM   3982 C CG  . ARG B 2 283 ? 158.771 123.456 103.363 1.00 85.11  ? 283 ARG B CG  1 
ATOM   3983 C CD  . ARG B 2 283 ? 159.188 122.145 102.734 1.00 85.04  ? 283 ARG B CD  1 
ATOM   3984 N NE  . ARG B 2 283 ? 160.285 121.527 103.465 1.00 84.64  ? 283 ARG B NE  1 
ATOM   3985 C CZ  . ARG B 2 283 ? 161.555 121.883 103.346 1.00 85.96  ? 283 ARG B CZ  1 
ATOM   3986 N NH1 . ARG B 2 283 ? 161.930 122.836 102.509 1.00 85.46  ? 283 ARG B NH1 1 
ATOM   3987 N NH2 . ARG B 2 283 ? 162.472 121.269 104.086 1.00 90.81  ? 283 ARG B NH2 1 
ATOM   3988 N N   . LEU B 2 284 ? 154.791 123.551 104.019 1.00 74.12  ? 284 LEU B N   1 
ATOM   3989 C CA  . LEU B 2 284 ? 154.124 123.285 105.283 1.00 79.92  ? 284 LEU B CA  1 
ATOM   3990 C C   . LEU B 2 284 ? 152.696 122.821 105.036 1.00 84.01  ? 284 LEU B C   1 
ATOM   3991 O O   . LEU B 2 284 ? 152.001 123.347 104.162 1.00 90.92  ? 284 LEU B O   1 
ATOM   3992 C CB  . LEU B 2 284 ? 154.122 124.525 106.181 1.00 81.12  ? 284 LEU B CB  1 
ATOM   3993 C CG  . LEU B 2 284 ? 155.403 124.800 106.972 1.00 82.88  ? 284 LEU B CG  1 
ATOM   3994 C CD1 . LEU B 2 284 ? 155.913 123.532 107.637 1.00 87.27  ? 284 LEU B CD1 1 
ATOM   3995 C CD2 . LEU B 2 284 ? 156.474 125.403 106.087 1.00 86.01  ? 284 LEU B CD2 1 
ATOM   3996 N N   . LEU B 2 285 ? 152.268 121.834 105.817 1.00 82.30  ? 285 LEU B N   1 
ATOM   3997 C CA  . LEU B 2 285 ? 150.930 121.259 105.742 1.00 79.34  ? 285 LEU B CA  1 
ATOM   3998 C C   . LEU B 2 285 ? 150.339 121.327 107.140 1.00 79.07  ? 285 LEU B C   1 
ATOM   3999 O O   . LEU B 2 285 ? 150.807 120.633 108.046 1.00 89.93  ? 285 LEU B O   1 
ATOM   4000 C CB  . LEU B 2 285 ? 150.991 119.820 105.236 1.00 78.29  ? 285 LEU B CB  1 
ATOM   4001 C CG  . LEU B 2 285 ? 149.707 119.032 104.994 1.00 81.98  ? 285 LEU B CG  1 
ATOM   4002 C CD1 . LEU B 2 285 ? 150.019 117.964 103.988 1.00 83.03  ? 285 LEU B CD1 1 
ATOM   4003 C CD2 . LEU B 2 285 ? 149.171 118.398 106.264 1.00 84.32  ? 285 LEU B CD2 1 
ATOM   4004 N N   . LEU B 2 286 ? 149.331 122.165 107.332 1.00 71.55  ? 286 LEU B N   1 
ATOM   4005 C CA  . LEU B 2 286 ? 148.779 122.402 108.654 1.00 74.90  ? 286 LEU B CA  1 
ATOM   4006 C C   . LEU B 2 286 ? 147.472 121.636 108.767 1.00 76.61  ? 286 LEU B C   1 
ATOM   4007 O O   . LEU B 2 286 ? 146.539 121.877 107.993 1.00 89.29  ? 286 LEU B O   1 
ATOM   4008 C CB  . LEU B 2 286 ? 148.563 123.894 108.912 1.00 78.49  ? 286 LEU B CB  1 
ATOM   4009 C CG  . LEU B 2 286 ? 149.761 124.854 108.992 1.00 79.62  ? 286 LEU B CG  1 
ATOM   4010 C CD1 . LEU B 2 286 ? 150.730 124.776 107.816 1.00 75.41  ? 286 LEU B CD1 1 
ATOM   4011 C CD2 . LEU B 2 286 ? 149.295 126.263 109.174 1.00 81.61  ? 286 LEU B CD2 1 
ATOM   4012 N N   . ALA B 2 287 ? 147.409 120.713 109.723 1.00 75.58  ? 287 ALA B N   1 
ATOM   4013 C CA  . ALA B 2 287 ? 146.243 119.863 109.904 1.00 76.20  ? 287 ALA B CA  1 
ATOM   4014 C C   . ALA B 2 287 ? 145.718 120.021 111.319 1.00 75.39  ? 287 ALA B C   1 
ATOM   4015 O O   . ALA B 2 287 ? 146.477 119.897 112.283 1.00 89.59  ? 287 ALA B O   1 
ATOM   4016 C CB  . ALA B 2 287 ? 146.580 118.395 109.628 1.00 81.84  ? 287 ALA B CB  1 
ATOM   4017 N N   . GLY B 2 288 ? 144.427 120.306 111.438 1.00 71.08  ? 288 GLY B N   1 
ATOM   4018 C CA  . GLY B 2 288 ? 143.788 120.290 112.734 1.00 78.52  ? 288 GLY B CA  1 
ATOM   4019 C C   . GLY B 2 288 ? 143.479 118.875 113.183 1.00 80.54  ? 288 GLY B C   1 
ATOM   4020 O O   . GLY B 2 288 ? 143.281 117.968 112.377 1.00 89.22  ? 288 GLY B O   1 
ATOM   4021 N N   . TYR B 2 289 ? 143.437 118.688 114.497 1.00 67.28  ? 289 TYR B N   1 
ATOM   4022 C CA  . TYR B 2 289 ? 143.211 117.380 115.088 1.00 72.03  ? 289 TYR B CA  1 
ATOM   4023 C C   . TYR B 2 289 ? 142.111 117.477 116.137 1.00 77.32  ? 289 TYR B C   1 
ATOM   4024 O O   . TYR B 2 289 ? 141.564 118.550 116.403 1.00 81.96  ? 289 TYR B O   1 
ATOM   4025 C CB  . TYR B 2 289 ? 144.496 116.824 115.711 1.00 73.04  ? 289 TYR B CB  1 
ATOM   4026 C CG  . TYR B 2 289 ? 145.569 116.454 114.717 1.00 67.64  ? 289 TYR B CG  1 
ATOM   4027 C CD1 . TYR B 2 289 ? 146.384 117.420 114.159 1.00 74.40  ? 289 TYR B CD1 1 
ATOM   4028 C CD2 . TYR B 2 289 ? 145.779 115.136 114.354 1.00 73.61  ? 289 TYR B CD2 1 
ATOM   4029 C CE1 . TYR B 2 289 ? 147.371 117.087 113.259 1.00 74.83  ? 289 TYR B CE1 1 
ATOM   4030 C CE2 . TYR B 2 289 ? 146.765 114.793 113.454 1.00 77.24  ? 289 TYR B CE2 1 
ATOM   4031 C CZ  . TYR B 2 289 ? 147.557 115.773 112.909 1.00 72.23  ? 289 TYR B CZ  1 
ATOM   4032 O OH  . TYR B 2 289 ? 148.541 115.440 112.010 1.00 80.27  ? 289 TYR B OH  1 
ATOM   4033 N N   . ASP B 2 290 ? 141.787 116.332 116.731 1.00 94.41  ? 290 ASP B N   1 
ATOM   4034 C CA  . ASP B 2 290 ? 140.882 116.259 117.867 1.00 95.79  ? 290 ASP B CA  1 
ATOM   4035 C C   . ASP B 2 290 ? 141.614 116.315 119.201 1.00 99.71  ? 290 ASP B C   1 
ATOM   4036 O O   . ASP B 2 290 ? 140.974 116.201 120.249 1.00 102.53 ? 290 ASP B O   1 
ATOM   4037 C CB  . ASP B 2 290 ? 140.040 114.982 117.789 1.00 95.78  ? 290 ASP B CB  1 
ATOM   4038 C CG  . ASP B 2 290 ? 138.670 115.140 118.414 1.00 100.77 ? 290 ASP B CG  1 
ATOM   4039 O OD1 . ASP B 2 290 ? 138.461 116.103 119.179 1.00 103.28 ? 290 ASP B OD1 1 
ATOM   4040 O OD2 . ASP B 2 290 ? 137.803 114.280 118.156 1.00 101.48 ? 290 ASP B OD2 1 
ATOM   4041 N N   . ASP B 2 291 ? 142.938 116.488 119.192 1.00 93.20  ? 291 ASP B N   1 
ATOM   4042 C CA  . ASP B 2 291 ? 143.687 116.745 120.414 1.00 90.73  ? 291 ASP B CA  1 
ATOM   4043 C C   . ASP B 2 291 ? 143.552 118.179 120.880 1.00 92.75  ? 291 ASP B C   1 
ATOM   4044 O O   . ASP B 2 291 ? 144.370 118.631 121.689 1.00 100.91 ? 291 ASP B O   1 
ATOM   4045 C CB  . ASP B 2 291 ? 145.169 116.414 120.231 1.00 89.92  ? 291 ASP B CB  1 
ATOM   4046 C CG  . ASP B 2 291 ? 145.395 115.151 119.447 1.00 99.25  ? 291 ASP B CG  1 
ATOM   4047 O OD1 . ASP B 2 291 ? 145.055 114.062 119.956 1.00 102.45 ? 291 ASP B OD1 1 
ATOM   4048 O OD2 . ASP B 2 291 ? 145.924 115.244 118.321 1.00 102.93 ? 291 ASP B OD2 1 
ATOM   4049 N N   . PHE B 2 292 ? 142.559 118.900 120.358 1.00 74.19  ? 292 PHE B N   1 
ATOM   4050 C CA  . PHE B 2 292 ? 142.296 120.288 120.726 1.00 81.75  ? 292 PHE B CA  1 
ATOM   4051 C C   . PHE B 2 292 ? 143.426 121.202 120.270 1.00 89.86  ? 292 PHE B C   1 
ATOM   4052 O O   . PHE B 2 292 ? 143.640 122.276 120.836 1.00 95.05  ? 292 PHE B O   1 
ATOM   4053 C CB  . PHE B 2 292 ? 142.051 120.444 122.234 1.00 80.96  ? 292 PHE B CB  1 
ATOM   4054 C CG  . PHE B 2 292 ? 140.891 119.635 122.772 1.00 79.57  ? 292 PHE B CG  1 
ATOM   4055 C CD1 . PHE B 2 292 ? 140.249 118.678 122.005 1.00 83.65  ? 292 PHE B CD1 1 
ATOM   4056 C CD2 . PHE B 2 292 ? 140.417 119.876 124.046 1.00 84.06  ? 292 PHE B CD2 1 
ATOM   4057 C CE1 . PHE B 2 292 ? 139.187 117.958 122.510 1.00 89.94  ? 292 PHE B CE1 1 
ATOM   4058 C CE2 . PHE B 2 292 ? 139.355 119.160 124.558 1.00 89.57  ? 292 PHE B CE2 1 
ATOM   4059 C CZ  . PHE B 2 292 ? 138.738 118.201 123.787 1.00 91.76  ? 292 PHE B CZ  1 
ATOM   4060 N N   . ASN B 2 293 ? 144.153 120.782 119.240 1.00 85.83  ? 293 ASN B N   1 
ATOM   4061 C CA  . ASN B 2 293 ? 145.259 121.565 118.709 1.00 85.64  ? 293 ASN B CA  1 
ATOM   4062 C C   . ASN B 2 293 ? 145.535 121.106 117.285 1.00 87.65  ? 293 ASN B C   1 
ATOM   4063 O O   . ASN B 2 293 ? 145.111 120.028 116.866 1.00 92.65  ? 293 ASN B O   1 
ATOM   4064 C CB  . ASN B 2 293 ? 146.502 121.436 119.596 1.00 85.90  ? 293 ASN B CB  1 
ATOM   4065 C CG  . ASN B 2 293 ? 147.104 120.048 119.559 1.00 86.63  ? 293 ASN B CG  1 
ATOM   4066 O OD1 . ASN B 2 293 ? 146.436 119.080 119.206 1.00 92.25  ? 293 ASN B OD1 1 
ATOM   4067 N ND2 . ASN B 2 293 ? 148.366 119.942 119.944 1.00 86.40  ? 293 ASN B ND2 1 
ATOM   4068 N N   . CYS B 2 294 ? 146.252 121.944 116.544 1.00 87.70  ? 294 CYS B N   1 
ATOM   4069 C CA  . CYS B 2 294 ? 146.627 121.647 115.172 1.00 84.87  ? 294 CYS B CA  1 
ATOM   4070 C C   . CYS B 2 294 ? 148.139 121.510 115.074 1.00 83.27  ? 294 CYS B C   1 
ATOM   4071 O O   . CYS B 2 294 ? 148.888 122.039 115.897 1.00 93.99  ? 294 CYS B O   1 
ATOM   4072 C CB  . CYS B 2 294 ? 146.127 122.725 114.204 1.00 87.96  ? 294 CYS B CB  1 
ATOM   4073 S SG  . CYS B 2 294 ? 146.578 124.409 114.644 1.00 100.72 ? 294 CYS B SG  1 
ATOM   4074 N N   . ASN B 2 295 ? 148.581 120.767 114.067 1.00 77.27  ? 295 ASN B N   1 
ATOM   4075 C CA  . ASN B 2 295 ? 149.993 120.474 113.889 1.00 81.00  ? 295 ASN B CA  1 
ATOM   4076 C C   . ASN B 2 295 ? 150.444 120.884 112.498 1.00 83.01  ? 295 ASN B C   1 
ATOM   4077 O O   . ASN B 2 295 ? 149.733 120.674 111.510 1.00 92.64  ? 295 ASN B O   1 
ATOM   4078 C CB  . ASN B 2 295 ? 150.287 118.989 114.121 1.00 84.81  ? 295 ASN B CB  1 
ATOM   4079 C CG  . ASN B 2 295 ? 149.828 118.511 115.484 1.00 93.50  ? 295 ASN B CG  1 
ATOM   4080 O OD1 . ASN B 2 295 ? 148.657 118.635 115.837 1.00 97.06  ? 295 ASN B OD1 1 
ATOM   4081 N ND2 . ASN B 2 295 ? 150.751 117.958 116.259 1.00 89.05  ? 295 ASN B ND2 1 
ATOM   4082 N N   . VAL B 2 296 ? 151.631 121.472 112.440 1.00 78.95  ? 296 VAL B N   1 
ATOM   4083 C CA  . VAL B 2 296 ? 152.272 121.897 111.205 1.00 76.93  ? 296 VAL B CA  1 
ATOM   4084 C C   . VAL B 2 296 ? 153.305 120.841 110.847 1.00 82.70  ? 296 VAL B C   1 
ATOM   4085 O O   . VAL B 2 296 ? 154.314 120.695 111.545 1.00 91.42  ? 296 VAL B O   1 
ATOM   4086 C CB  . VAL B 2 296 ? 152.925 123.275 111.366 1.00 81.54  ? 296 VAL B CB  1 
ATOM   4087 C CG1 . VAL B 2 296 ? 153.262 123.865 110.020 1.00 85.42  ? 296 VAL B CG1 1 
ATOM   4088 C CG2 . VAL B 2 296 ? 152.008 124.202 112.143 1.00 84.98  ? 296 VAL B CG2 1 
ATOM   4089 N N   . TRP B 2 297 ? 153.052 120.102 109.770 1.00 81.97  ? 297 TRP B N   1 
ATOM   4090 C CA  . TRP B 2 297 ? 153.966 119.096 109.261 1.00 78.37  ? 297 TRP B CA  1 
ATOM   4091 C C   . TRP B 2 297 ? 154.786 119.677 108.119 1.00 77.47  ? 297 TRP B C   1 
ATOM   4092 O O   . TRP B 2 297 ? 154.335 120.572 107.402 1.00 87.61  ? 297 TRP B O   1 
ATOM   4093 C CB  . TRP B 2 297 ? 153.211 117.868 108.753 1.00 84.42  ? 297 TRP B CB  1 
ATOM   4094 C CG  . TRP B 2 297 ? 152.426 117.142 109.788 1.00 88.30  ? 297 TRP B CG  1 
ATOM   4095 C CD1 . TRP B 2 297 ? 151.183 117.457 110.244 1.00 86.37  ? 297 TRP B CD1 1 
ATOM   4096 C CD2 . TRP B 2 297 ? 152.837 115.980 110.512 1.00 86.72  ? 297 TRP B CD2 1 
ATOM   4097 N NE1 . TRP B 2 297 ? 150.786 116.556 111.199 1.00 88.29  ? 297 TRP B NE1 1 
ATOM   4098 C CE2 . TRP B 2 297 ? 151.788 115.640 111.384 1.00 86.20  ? 297 TRP B CE2 1 
ATOM   4099 C CE3 . TRP B 2 297 ? 153.991 115.194 110.507 1.00 86.31  ? 297 TRP B CE3 1 
ATOM   4100 C CZ2 . TRP B 2 297 ? 151.857 114.548 112.241 1.00 87.43  ? 297 TRP B CZ2 1 
ATOM   4101 C CZ3 . TRP B 2 297 ? 154.057 114.111 111.355 1.00 86.84  ? 297 TRP B CZ3 1 
ATOM   4102 C CH2 . TRP B 2 297 ? 152.997 113.797 112.212 1.00 90.38  ? 297 TRP B CH2 1 
ATOM   4103 N N   . ASP B 2 298 ? 155.994 119.159 107.953 1.00 83.09  ? 298 ASP B N   1 
ATOM   4104 C CA  . ASP B 2 298 ? 156.814 119.487 106.797 1.00 86.89  ? 298 ASP B CA  1 
ATOM   4105 C C   . ASP B 2 298 ? 156.536 118.454 105.713 1.00 91.22  ? 298 ASP B C   1 
ATOM   4106 O O   . ASP B 2 298 ? 156.839 117.269 105.888 1.00 98.90  ? 298 ASP B O   1 
ATOM   4107 C CB  . ASP B 2 298 ? 158.294 119.506 107.165 1.00 90.29  ? 298 ASP B CB  1 
ATOM   4108 C CG  . ASP B 2 298 ? 159.188 119.670 105.961 1.00 96.41  ? 298 ASP B CG  1 
ATOM   4109 O OD1 . ASP B 2 298 ? 159.591 118.647 105.374 1.00 98.68  ? 298 ASP B OD1 1 
ATOM   4110 O OD2 . ASP B 2 298 ? 159.498 120.825 105.605 1.00 98.46  ? 298 ASP B OD2 1 
ATOM   4111 N N   . ALA B 2 299 ? 155.958 118.902 104.597 1.00 88.34  ? 299 ALA B N   1 
ATOM   4112 C CA  . ALA B 2 299 ? 155.472 117.967 103.587 1.00 88.40  ? 299 ALA B CA  1 
ATOM   4113 C C   . ALA B 2 299 ? 156.608 117.175 102.955 1.00 92.36  ? 299 ALA B C   1 
ATOM   4114 O O   . ALA B 2 299 ? 156.452 115.987 102.652 1.00 103.51 ? 299 ALA B O   1 
ATOM   4115 C CB  . ALA B 2 299 ? 154.685 118.717 102.515 1.00 88.41  ? 299 ALA B CB  1 
ATOM   4116 N N   . LEU B 2 300 ? 157.758 117.814 102.745 1.00 94.38  ? 300 LEU B N   1 
ATOM   4117 C CA  . LEU B 2 300 ? 158.837 117.163 102.009 1.00 100.36 ? 300 LEU B CA  1 
ATOM   4118 C C   . LEU B 2 300 ? 159.553 116.116 102.856 1.00 98.90  ? 300 LEU B C   1 
ATOM   4119 O O   . LEU B 2 300 ? 160.034 115.109 102.325 1.00 99.12  ? 300 LEU B O   1 
ATOM   4120 C CB  . LEU B 2 300 ? 159.827 118.209 101.500 1.00 99.15  ? 300 LEU B CB  1 
ATOM   4121 C CG  . LEU B 2 300 ? 159.308 119.190 100.449 1.00 100.07 ? 300 LEU B CG  1 
ATOM   4122 C CD1 . LEU B 2 300 ? 160.445 119.642 99.554  1.00 102.51 ? 300 LEU B CD1 1 
ATOM   4123 C CD2 . LEU B 2 300 ? 158.201 118.561 99.620  1.00 97.91  ? 300 LEU B CD2 1 
ATOM   4124 N N   . LYS B 2 301 ? 159.647 116.334 104.166 1.00 93.28  ? 301 LYS B N   1 
ATOM   4125 C CA  . LYS B 2 301 ? 160.393 115.436 105.037 1.00 93.07  ? 301 LYS B CA  1 
ATOM   4126 C C   . LYS B 2 301 ? 159.514 114.668 106.012 1.00 99.61  ? 301 LYS B C   1 
ATOM   4127 O O   . LYS B 2 301 ? 160.030 113.819 106.746 1.00 105.72 ? 301 LYS B O   1 
ATOM   4128 C CB  . LYS B 2 301 ? 161.461 116.216 105.810 1.00 96.45  ? 301 LYS B CB  1 
ATOM   4129 C CG  . LYS B 2 301 ? 162.878 115.770 105.512 1.00 99.98  ? 301 LYS B CG  1 
ATOM   4130 C CD  . LYS B 2 301 ? 163.894 116.630 106.239 1.00 102.90 ? 301 LYS B CD  1 
ATOM   4131 C CE  . LYS B 2 301 ? 165.302 116.093 106.050 1.00 103.76 ? 301 LYS B CE  1 
ATOM   4132 N NZ  . LYS B 2 301 ? 166.322 116.965 106.694 1.00 105.09 ? 301 LYS B NZ  1 
ATOM   4133 N N   . ALA B 2 302 ? 158.211 114.947 106.047 1.00 93.42  ? 302 ALA B N   1 
ATOM   4134 C CA  . ALA B 2 302 ? 157.256 114.211 106.878 1.00 91.16  ? 302 ALA B CA  1 
ATOM   4135 C C   . ALA B 2 302 ? 157.603 114.288 108.361 1.00 93.25  ? 302 ALA B C   1 
ATOM   4136 O O   . ALA B 2 302 ? 157.257 113.393 109.135 1.00 95.97  ? 302 ALA B O   1 
ATOM   4137 C CB  . ALA B 2 302 ? 157.140 112.751 106.436 1.00 91.39  ? 302 ALA B CB  1 
ATOM   4138 N N   . ASP B 2 303 ? 158.280 115.354 108.771 1.00 94.76  ? 303 ASP B N   1 
ATOM   4139 C CA  . ASP B 2 303 ? 158.641 115.574 110.164 1.00 91.02  ? 303 ASP B CA  1 
ATOM   4140 C C   . ASP B 2 303 ? 157.805 116.717 110.716 1.00 90.53  ? 303 ASP B C   1 
ATOM   4141 O O   . ASP B 2 303 ? 157.710 117.778 110.091 1.00 101.25 ? 303 ASP B O   1 
ATOM   4142 C CB  . ASP B 2 303 ? 160.131 115.889 110.303 1.00 94.20  ? 303 ASP B CB  1 
ATOM   4143 C CG  . ASP B 2 303 ? 160.930 114.707 110.814 1.00 99.05  ? 303 ASP B CG  1 
ATOM   4144 O OD1 . ASP B 2 303 ? 160.486 114.067 111.790 1.00 100.96 ? 303 ASP B OD1 1 
ATOM   4145 O OD2 . ASP B 2 303 ? 162.000 114.417 110.240 1.00 97.59  ? 303 ASP B OD2 1 
ATOM   4146 N N   . ARG B 2 304 ? 157.197 116.497 111.881 1.00 78.33  ? 304 ARG B N   1 
ATOM   4147 C CA  . ARG B 2 304 ? 156.342 117.505 112.494 1.00 81.15  ? 304 ARG B CA  1 
ATOM   4148 C C   . ARG B 2 304 ? 157.114 118.789 112.761 1.00 83.46  ? 304 ARG B C   1 
ATOM   4149 O O   . ARG B 2 304 ? 158.006 118.823 113.614 1.00 86.17  ? 304 ARG B O   1 
ATOM   4150 C CB  . ARG B 2 304 ? 155.735 116.974 113.791 1.00 82.46  ? 304 ARG B CB  1 
ATOM   4151 C CG  . ARG B 2 304 ? 154.894 117.993 114.526 1.00 85.63  ? 304 ARG B CG  1 
ATOM   4152 C CD  . ARG B 2 304 ? 153.651 117.360 115.113 1.00 84.33  ? 304 ARG B CD  1 
ATOM   4153 N NE  . ARG B 2 304 ? 153.965 116.265 116.022 1.00 84.20  ? 304 ARG B NE  1 
ATOM   4154 C CZ  . ARG B 2 304 ? 154.422 116.422 117.256 1.00 91.77  ? 304 ARG B CZ  1 
ATOM   4155 N NH1 . ARG B 2 304 ? 154.628 117.623 117.770 1.00 87.44  ? 304 ARG B NH1 1 
ATOM   4156 N NH2 . ARG B 2 304 ? 154.678 115.346 117.994 1.00 92.16  ? 304 ARG B NH2 1 
ATOM   4157 N N   . ALA B 2 305 ? 156.774 119.853 112.034 1.00 87.75  ? 305 ALA B N   1 
ATOM   4158 C CA  . ALA B 2 305 ? 157.484 121.115 112.190 1.00 86.35  ? 305 ALA B CA  1 
ATOM   4159 C C   . ALA B 2 305 ? 157.088 121.832 113.473 1.00 87.67  ? 305 ALA B C   1 
ATOM   4160 O O   . ALA B 2 305 ? 157.947 122.390 114.163 1.00 92.98  ? 305 ALA B O   1 
ATOM   4161 C CB  . ALA B 2 305 ? 157.229 122.015 110.981 1.00 91.80  ? 305 ALA B CB  1 
ATOM   4162 N N   . GLY B 2 306 ? 155.804 121.830 113.810 1.00 80.53  ? 306 GLY B N   1 
ATOM   4163 C CA  . GLY B 2 306 ? 155.370 122.594 114.968 1.00 82.77  ? 306 GLY B CA  1 
ATOM   4164 C C   . GLY B 2 306 ? 153.984 122.195 115.415 1.00 79.26  ? 306 GLY B C   1 
ATOM   4165 O O   . GLY B 2 306 ? 153.298 121.405 114.764 1.00 88.29  ? 306 GLY B O   1 
ATOM   4166 N N   . VAL B 2 307 ? 153.579 122.762 116.546 1.00 59.68  ? 307 VAL B N   1 
ATOM   4167 C CA  . VAL B 2 307 ? 152.266 122.508 117.125 1.00 64.86  ? 307 VAL B CA  1 
ATOM   4168 C C   . VAL B 2 307 ? 151.670 123.827 117.593 1.00 65.05  ? 307 VAL B C   1 
ATOM   4169 O O   . VAL B 2 307 ? 152.311 124.574 118.339 1.00 76.55  ? 307 VAL B O   1 
ATOM   4170 C CB  . VAL B 2 307 ? 152.343 121.496 118.284 1.00 74.10  ? 307 VAL B CB  1 
ATOM   4171 C CG1 . VAL B 2 307 ? 153.480 121.848 119.232 1.00 76.44  ? 307 VAL B CG1 1 
ATOM   4172 C CG2 . VAL B 2 307 ? 151.032 121.461 119.033 1.00 75.63  ? 307 VAL B CG2 1 
ATOM   4173 N N   . LEU B 2 308 ? 150.457 124.128 117.137 1.00 67.65  ? 308 LEU B N   1 
ATOM   4174 C CA  . LEU B 2 308 ? 149.753 125.338 117.554 1.00 73.04  ? 308 LEU B CA  1 
ATOM   4175 C C   . LEU B 2 308 ? 148.689 124.980 118.590 1.00 78.99  ? 308 LEU B C   1 
ATOM   4176 O O   . LEU B 2 308 ? 147.494 124.907 118.308 1.00 80.38  ? 308 LEU B O   1 
ATOM   4177 C CB  . LEU B 2 308 ? 149.143 126.041 116.346 1.00 75.14  ? 308 LEU B CB  1 
ATOM   4178 C CG  . LEU B 2 308 ? 149.877 125.977 115.006 1.00 77.15  ? 308 LEU B CG  1 
ATOM   4179 C CD1 . LEU B 2 308 ? 149.194 126.878 113.995 1.00 77.82  ? 308 LEU B CD1 1 
ATOM   4180 C CD2 . LEU B 2 308 ? 151.337 126.354 115.152 1.00 78.00  ? 308 LEU B CD2 1 
ATOM   4181 N N   . ALA B 2 309 ? 149.149 124.752 119.816 1.00 82.85  ? 309 ALA B N   1 
ATOM   4182 C CA  . ALA B 2 309 ? 148.257 124.377 120.910 1.00 80.74  ? 309 ALA B CA  1 
ATOM   4183 C C   . ALA B 2 309 ? 147.661 125.643 121.507 1.00 79.47  ? 309 ALA B C   1 
ATOM   4184 O O   . ALA B 2 309 ? 148.275 126.294 122.354 1.00 86.63  ? 309 ALA B O   1 
ATOM   4185 C CB  . ALA B 2 309 ? 149.006 123.566 121.961 1.00 79.18  ? 309 ALA B CB  1 
ATOM   4186 N N   . GLY B 2 310 ? 146.458 126.000 121.067 1.00 65.30  ? 310 GLY B N   1 
ATOM   4187 C CA  . GLY B 2 310 ? 145.832 127.207 121.563 1.00 69.85  ? 310 GLY B CA  1 
ATOM   4188 C C   . GLY B 2 310 ? 144.329 127.137 121.730 1.00 74.89  ? 310 GLY B C   1 
ATOM   4189 O O   . GLY B 2 310 ? 143.694 128.150 122.030 1.00 84.16  ? 310 GLY B O   1 
ATOM   4190 N N   . HIS B 2 311 ? 143.742 125.959 121.555 1.00 71.12  ? 311 HIS B N   1 
ATOM   4191 C CA  . HIS B 2 311 ? 142.301 125.796 121.658 1.00 75.21  ? 311 HIS B CA  1 
ATOM   4192 C C   . HIS B 2 311 ? 141.964 124.761 122.720 1.00 76.84  ? 311 HIS B C   1 
ATOM   4193 O O   . HIS B 2 311 ? 142.752 123.853 122.998 1.00 82.06  ? 311 HIS B O   1 
ATOM   4194 C CB  . HIS B 2 311 ? 141.688 125.380 120.319 1.00 77.93  ? 311 HIS B CB  1 
ATOM   4195 C CG  . HIS B 2 311 ? 141.867 126.393 119.233 1.00 82.24  ? 311 HIS B CG  1 
ATOM   4196 N ND1 . HIS B 2 311 ? 140.979 127.426 119.028 1.00 81.47  ? 311 HIS B ND1 1 
ATOM   4197 C CD2 . HIS B 2 311 ? 142.830 126.533 118.293 1.00 83.87  ? 311 HIS B CD2 1 
ATOM   4198 C CE1 . HIS B 2 311 ? 141.387 128.159 118.008 1.00 80.43  ? 311 HIS B CE1 1 
ATOM   4199 N NE2 . HIS B 2 311 ? 142.509 127.639 117.545 1.00 84.96  ? 311 HIS B NE2 1 
ATOM   4200 N N   . ASP B 2 312 ? 140.784 124.911 123.317 1.00 84.68  ? 312 ASP B N   1 
ATOM   4201 C CA  . ASP B 2 312 ? 140.306 123.991 124.337 1.00 90.39  ? 312 ASP B CA  1 
ATOM   4202 C C   . ASP B 2 312 ? 139.289 122.989 123.803 1.00 91.81  ? 312 ASP B C   1 
ATOM   4203 O O   . ASP B 2 312 ? 138.659 122.278 124.591 1.00 96.28  ? 312 ASP B O   1 
ATOM   4204 C CB  . ASP B 2 312 ? 139.782 124.788 125.551 1.00 93.20  ? 312 ASP B CB  1 
ATOM   4205 C CG  . ASP B 2 312 ? 138.281 125.145 125.494 1.00 100.42 ? 312 ASP B CG  1 
ATOM   4206 O OD1 . ASP B 2 312 ? 137.519 124.732 124.598 1.00 102.39 ? 312 ASP B OD1 1 
ATOM   4207 O OD2 . ASP B 2 312 ? 137.852 125.882 126.406 1.00 99.75  ? 312 ASP B OD2 1 
ATOM   4208 N N   . ASN B 2 313 ? 139.121 122.914 122.486 1.00 81.79  ? 313 ASN B N   1 
ATOM   4209 C CA  . ASN B 2 313 ? 138.241 121.934 121.868 1.00 81.70  ? 313 ASN B CA  1 
ATOM   4210 C C   . ASN B 2 313 ? 138.774 121.611 120.480 1.00 84.91  ? 313 ASN B C   1 
ATOM   4211 O O   . ASN B 2 313 ? 139.824 122.109 120.065 1.00 87.28  ? 313 ASN B O   1 
ATOM   4212 C CB  . ASN B 2 313 ? 136.799 122.438 121.811 1.00 84.60  ? 313 ASN B CB  1 
ATOM   4213 C CG  . ASN B 2 313 ? 135.799 121.360 122.153 1.00 84.77  ? 313 ASN B CG  1 
ATOM   4214 O OD1 . ASN B 2 313 ? 135.907 120.230 121.681 1.00 82.30  ? 313 ASN B OD1 1 
ATOM   4215 N ND2 . ASN B 2 313 ? 134.815 121.701 122.973 1.00 87.62  ? 313 ASN B ND2 1 
ATOM   4216 N N   . ARG B 2 314 ? 138.033 120.771 119.760 1.00 85.48  ? 314 ARG B N   1 
ATOM   4217 C CA  . ARG B 2 314 ? 138.467 120.308 118.448 1.00 86.71  ? 314 ARG B CA  1 
ATOM   4218 C C   . ARG B 2 314 ? 138.721 121.469 117.499 1.00 91.04  ? 314 ARG B C   1 
ATOM   4219 O O   . ARG B 2 314 ? 137.875 122.351 117.337 1.00 100.26 ? 314 ARG B O   1 
ATOM   4220 C CB  . ARG B 2 314 ? 137.415 119.380 117.844 1.00 84.94  ? 314 ARG B CB  1 
ATOM   4221 C CG  . ARG B 2 314 ? 137.991 118.262 117.005 1.00 86.50  ? 314 ARG B CG  1 
ATOM   4222 C CD  . ARG B 2 314 ? 136.995 117.791 115.963 1.00 91.38  ? 314 ARG B CD  1 
ATOM   4223 N NE  . ARG B 2 314 ? 136.100 116.765 116.482 1.00 88.65  ? 314 ARG B NE  1 
ATOM   4224 C CZ  . ARG B 2 314 ? 136.126 115.493 116.111 1.00 88.18  ? 314 ARG B CZ  1 
ATOM   4225 N NH1 . ARG B 2 314 ? 136.997 115.051 115.220 1.00 85.16  ? 314 ARG B NH1 1 
ATOM   4226 N NH2 . ARG B 2 314 ? 135.259 114.643 116.651 1.00 91.02  ? 314 ARG B NH2 1 
ATOM   4227 N N   . VAL B 2 315 ? 139.888 121.455 116.860 1.00 77.01  ? 315 VAL B N   1 
ATOM   4228 C CA  . VAL B 2 315 ? 140.167 122.373 115.761 1.00 74.21  ? 315 VAL B CA  1 
ATOM   4229 C C   . VAL B 2 315 ? 139.357 121.901 114.560 1.00 80.38  ? 315 VAL B C   1 
ATOM   4230 O O   . VAL B 2 315 ? 139.676 120.878 113.950 1.00 82.24  ? 315 VAL B O   1 
ATOM   4231 C CB  . VAL B 2 315 ? 141.663 122.429 115.440 1.00 75.83  ? 315 VAL B CB  1 
ATOM   4232 C CG1 . VAL B 2 315 ? 141.890 123.060 114.082 1.00 79.61  ? 315 VAL B CG1 1 
ATOM   4233 C CG2 . VAL B 2 315 ? 142.404 123.197 116.518 1.00 82.24  ? 315 VAL B CG2 1 
ATOM   4234 N N   . SER B 2 316 ? 138.297 122.633 114.227 1.00 82.48  ? 316 SER B N   1 
ATOM   4235 C CA  . SER B 2 316 ? 137.368 122.172 113.203 1.00 75.81  ? 316 SER B CA  1 
ATOM   4236 C C   . SER B 2 316 ? 137.727 122.668 111.810 1.00 82.42  ? 316 SER B C   1 
ATOM   4237 O O   . SER B 2 316 ? 137.530 121.941 110.831 1.00 88.96  ? 316 SER B O   1 
ATOM   4238 C CB  . SER B 2 316 ? 135.945 122.605 113.552 1.00 73.74  ? 316 SER B CB  1 
ATOM   4239 O OG  . SER B 2 316 ? 135.830 124.015 113.562 1.00 81.60  ? 316 SER B OG  1 
ATOM   4240 N N   . CYS B 2 317 ? 138.245 123.887 111.687 1.00 80.83  ? 317 CYS B N   1 
ATOM   4241 C CA  . CYS B 2 317 ? 138.538 124.457 110.381 1.00 75.77  ? 317 CYS B CA  1 
ATOM   4242 C C   . CYS B 2 317 ? 139.911 125.108 110.387 1.00 77.38  ? 317 CYS B C   1 
ATOM   4243 O O   . CYS B 2 317 ? 140.294 125.760 111.361 1.00 84.50  ? 317 CYS B O   1 
ATOM   4244 C CB  . CYS B 2 317 ? 137.477 125.480 109.978 1.00 82.38  ? 317 CYS B CB  1 
ATOM   4245 S SG  . CYS B 2 317 ? 137.230 126.796 111.184 1.00 104.57 ? 317 CYS B SG  1 
ATOM   4246 N N   . LEU B 2 318 ? 140.639 124.935 109.288 1.00 77.98  ? 318 LEU B N   1 
ATOM   4247 C CA  . LEU B 2 318 ? 141.946 125.544 109.104 1.00 77.96  ? 318 LEU B CA  1 
ATOM   4248 C C   . LEU B 2 318 ? 141.997 126.182 107.725 1.00 81.24  ? 318 LEU B C   1 
ATOM   4249 O O   . LEU B 2 318 ? 141.531 125.595 106.746 1.00 91.43  ? 318 LEU B O   1 
ATOM   4250 C CB  . LEU B 2 318 ? 143.070 124.512 109.246 1.00 79.39  ? 318 LEU B CB  1 
ATOM   4251 C CG  . LEU B 2 318 ? 144.445 124.980 109.716 1.00 83.86  ? 318 LEU B CG  1 
ATOM   4252 C CD1 . LEU B 2 318 ? 145.157 123.852 110.436 1.00 83.82  ? 318 LEU B CD1 1 
ATOM   4253 C CD2 . LEU B 2 318 ? 145.276 125.474 108.549 1.00 85.99  ? 318 LEU B CD2 1 
ATOM   4254 N N   . GLY B 2 319 ? 142.557 127.378 107.656 1.00 63.17  ? 319 GLY B N   1 
ATOM   4255 C CA  . GLY B 2 319 ? 142.709 128.068 106.387 1.00 64.83  ? 319 GLY B CA  1 
ATOM   4256 C C   . GLY B 2 319 ? 143.976 128.887 106.380 1.00 66.78  ? 319 GLY B C   1 
ATOM   4257 O O   . GLY B 2 319 ? 144.448 129.341 107.426 1.00 76.19  ? 319 GLY B O   1 
ATOM   4258 N N   . VAL B 2 320 ? 144.531 129.078 105.188 1.00 63.78  ? 320 VAL B N   1 
ATOM   4259 C CA  . VAL B 2 320 ? 145.758 129.841 105.002 1.00 61.89  ? 320 VAL B CA  1 
ATOM   4260 C C   . VAL B 2 320 ? 145.488 130.939 103.986 1.00 72.46  ? 320 VAL B C   1 
ATOM   4261 O O   . VAL B 2 320 ? 144.883 130.685 102.939 1.00 80.17  ? 320 VAL B O   1 
ATOM   4262 C CB  . VAL B 2 320 ? 146.923 128.944 104.544 1.00 60.64  ? 320 VAL B CB  1 
ATOM   4263 C CG1 . VAL B 2 320 ? 148.054 129.781 103.981 1.00 68.51  ? 320 VAL B CG1 1 
ATOM   4264 C CG2 . VAL B 2 320 ? 147.419 128.100 105.700 1.00 65.20  ? 320 VAL B CG2 1 
ATOM   4265 N N   . THR B 2 321 ? 145.927 132.156 104.299 1.00 79.76  ? 321 THR B N   1 
ATOM   4266 C CA  . THR B 2 321 ? 145.715 133.288 103.409 1.00 75.50  ? 321 THR B CA  1 
ATOM   4267 C C   . THR B 2 321 ? 146.425 133.069 102.081 1.00 76.42  ? 321 THR B C   1 
ATOM   4268 O O   . THR B 2 321 ? 147.443 132.378 102.001 1.00 82.45  ? 321 THR B O   1 
ATOM   4269 C CB  . THR B 2 321 ? 146.224 134.576 104.052 1.00 82.39  ? 321 THR B CB  1 
ATOM   4270 O OG1 . THR B 2 321 ? 147.470 134.321 104.712 1.00 89.90  ? 321 THR B OG1 1 
ATOM   4271 C CG2 . THR B 2 321 ? 145.225 135.106 105.054 1.00 80.68  ? 321 THR B CG2 1 
ATOM   4272 N N   . ASP B 2 322 ? 145.874 133.673 101.028 1.00 83.66  ? 322 ASP B N   1 
ATOM   4273 C CA  . ASP B 2 322 ? 146.426 133.499 99.691  1.00 87.57  ? 322 ASP B CA  1 
ATOM   4274 C C   . ASP B 2 322 ? 147.829 134.076 99.553  1.00 88.60  ? 322 ASP B C   1 
ATOM   4275 O O   . ASP B 2 322 ? 148.560 133.670 98.645  1.00 92.89  ? 322 ASP B O   1 
ATOM   4276 C CB  . ASP B 2 322 ? 145.496 134.129 98.658  1.00 90.73  ? 322 ASP B CB  1 
ATOM   4277 C CG  . ASP B 2 322 ? 144.102 133.541 98.702  1.00 95.43  ? 322 ASP B CG  1 
ATOM   4278 O OD1 . ASP B 2 322 ? 143.507 133.501 99.799  1.00 96.40  ? 322 ASP B OD1 1 
ATOM   4279 O OD2 . ASP B 2 322 ? 143.601 133.116 97.640  1.00 96.28  ? 322 ASP B OD2 1 
ATOM   4280 N N   . ASP B 2 323 ? 148.219 135.012 100.412 1.00 82.10  ? 323 ASP B N   1 
ATOM   4281 C CA  . ASP B 2 323 ? 149.584 135.516 100.413 1.00 87.02  ? 323 ASP B CA  1 
ATOM   4282 C C   . ASP B 2 323 ? 150.466 134.807 101.430 1.00 93.91  ? 323 ASP B C   1 
ATOM   4283 O O   . ASP B 2 323 ? 151.653 135.130 101.531 1.00 98.79  ? 323 ASP B O   1 
ATOM   4284 C CB  . ASP B 2 323 ? 149.598 137.020 100.691 1.00 94.13  ? 323 ASP B CB  1 
ATOM   4285 C CG  . ASP B 2 323 ? 148.764 137.388 101.890 1.00 98.73  ? 323 ASP B CG  1 
ATOM   4286 O OD1 . ASP B 2 323 ? 147.935 136.555 102.297 1.00 98.54  ? 323 ASP B OD1 1 
ATOM   4287 O OD2 . ASP B 2 323 ? 148.960 138.490 102.445 1.00 100.10 ? 323 ASP B OD2 1 
ATOM   4288 N N   . GLY B 2 324 ? 149.917 133.855 102.178 1.00 84.75  ? 324 GLY B N   1 
ATOM   4289 C CA  . GLY B 2 324 ? 150.685 133.160 103.192 1.00 81.05  ? 324 GLY B CA  1 
ATOM   4290 C C   . GLY B 2 324 ? 151.110 134.026 104.354 1.00 79.21  ? 324 GLY B C   1 
ATOM   4291 O O   . GLY B 2 324 ? 152.215 133.857 104.871 1.00 73.51  ? 324 GLY B O   1 
ATOM   4292 N N   . MET B 2 325 ? 150.259 134.951 104.784 1.00 90.39  ? 325 MET B N   1 
ATOM   4293 C CA  . MET B 2 325 ? 150.585 135.848 105.880 1.00 88.67  ? 325 MET B CA  1 
ATOM   4294 C C   . MET B 2 325 ? 149.884 135.481 107.177 1.00 90.71  ? 325 MET B C   1 
ATOM   4295 O O   . MET B 2 325 ? 150.202 136.059 108.220 1.00 100.52 ? 325 MET B O   1 
ATOM   4296 C CB  . MET B 2 325 ? 150.234 137.289 105.503 1.00 90.52  ? 325 MET B CB  1 
ATOM   4297 C CG  . MET B 2 325 ? 151.225 138.321 105.999 1.00 94.36  ? 325 MET B CG  1 
ATOM   4298 S SD  . MET B 2 325 ? 152.763 138.376 105.070 1.00 102.49 ? 325 MET B SD  1 
ATOM   4299 C CE  . MET B 2 325 ? 152.295 139.430 103.702 1.00 92.94  ? 325 MET B CE  1 
ATOM   4300 N N   . ALA B 2 326 ? 148.948 134.539 107.145 1.00 69.17  ? 326 ALA B N   1 
ATOM   4301 C CA  . ALA B 2 326 ? 148.176 134.221 108.335 1.00 69.31  ? 326 ALA B CA  1 
ATOM   4302 C C   . ALA B 2 326 ? 147.652 132.802 108.225 1.00 71.38  ? 326 ALA B C   1 
ATOM   4303 O O   . ALA B 2 326 ? 147.581 132.228 107.136 1.00 80.05  ? 326 ALA B O   1 
ATOM   4304 C CB  . ALA B 2 326 ? 147.016 135.198 108.527 1.00 74.14  ? 326 ALA B CB  1 
ATOM   4305 N N   . VAL B 2 327 ? 147.288 132.241 109.374 1.00 76.79  ? 327 VAL B N   1 
ATOM   4306 C CA  . VAL B 2 327 ? 146.660 130.927 109.442 1.00 70.36  ? 327 VAL B CA  1 
ATOM   4307 C C   . VAL B 2 327 ? 145.457 131.030 110.363 1.00 71.22  ? 327 VAL B C   1 
ATOM   4308 O O   . VAL B 2 327 ? 145.615 131.141 111.582 1.00 79.67  ? 327 VAL B O   1 
ATOM   4309 C CB  . VAL B 2 327 ? 147.622 129.848 109.942 1.00 69.38  ? 327 VAL B CB  1 
ATOM   4310 C CG1 . VAL B 2 327 ? 146.872 128.550 110.135 1.00 71.15  ? 327 VAL B CG1 1 
ATOM   4311 C CG2 . VAL B 2 327 ? 148.758 129.680 108.965 1.00 73.27  ? 327 VAL B CG2 1 
ATOM   4312 N N   . ALA B 2 328 ? 144.265 130.982 109.796 1.00 71.36  ? 328 ALA B N   1 
ATOM   4313 C CA  . ALA B 2 328 ? 143.060 130.993 110.602 1.00 71.49  ? 328 ALA B CA  1 
ATOM   4314 C C   . ALA B 2 328 ? 142.740 129.578 111.054 1.00 71.48  ? 328 ALA B C   1 
ATOM   4315 O O   . ALA B 2 328 ? 142.769 128.637 110.257 1.00 82.91  ? 328 ALA B O   1 
ATOM   4316 C CB  . ALA B 2 328 ? 141.889 131.577 109.819 1.00 77.18  ? 328 ALA B CB  1 
ATOM   4317 N N   . THR B 2 329 ? 142.446 129.431 112.341 1.00 69.84  ? 329 THR B N   1 
ATOM   4318 C CA  . THR B 2 329 ? 142.117 128.140 112.931 1.00 74.24  ? 329 THR B CA  1 
ATOM   4319 C C   . THR B 2 329 ? 140.883 128.335 113.797 1.00 70.50  ? 329 THR B C   1 
ATOM   4320 O O   . THR B 2 329 ? 140.953 128.988 114.842 1.00 79.08  ? 329 THR B O   1 
ATOM   4321 C CB  . THR B 2 329 ? 143.286 127.595 113.752 1.00 76.95  ? 329 THR B CB  1 
ATOM   4322 O OG1 . THR B 2 329 ? 144.332 127.169 112.871 1.00 77.52  ? 329 THR B OG1 1 
ATOM   4323 C CG2 . THR B 2 329 ? 142.843 126.419 114.588 1.00 75.48  ? 329 THR B CG2 1 
ATOM   4324 N N   . GLY B 2 330 ? 139.752 127.799 113.351 1.00 72.68  ? 330 GLY B N   1 
ATOM   4325 C CA  . GLY B 2 330 ? 138.507 127.906 114.085 1.00 78.92  ? 330 GLY B CA  1 
ATOM   4326 C C   . GLY B 2 330 ? 138.187 126.582 114.756 1.00 78.96  ? 330 GLY B C   1 
ATOM   4327 O O   . GLY B 2 330 ? 138.273 125.521 114.131 1.00 84.63  ? 330 GLY B O   1 
ATOM   4328 N N   . SER B 2 331 ? 137.809 126.660 116.029 1.00 78.34  ? 331 SER B N   1 
ATOM   4329 C CA  . SER B 2 331 ? 137.633 125.461 116.832 1.00 75.41  ? 331 SER B CA  1 
ATOM   4330 C C   . SER B 2 331 ? 136.238 125.425 117.436 1.00 76.59  ? 331 SER B C   1 
ATOM   4331 O O   . SER B 2 331 ? 135.464 126.380 117.339 1.00 84.56  ? 331 SER B O   1 
ATOM   4332 C CB  . SER B 2 331 ? 138.689 125.372 117.938 1.00 81.97  ? 331 SER B CB  1 
ATOM   4333 O OG  . SER B 2 331 ? 138.876 126.631 118.557 1.00 88.42  ? 331 SER B OG  1 
ATOM   4334 N N   . TRP B 2 332 ? 135.928 124.294 118.071 1.00 80.19  ? 332 TRP B N   1 
ATOM   4335 C CA  . TRP B 2 332 ? 134.623 124.088 118.687 1.00 81.85  ? 332 TRP B CA  1 
ATOM   4336 C C   . TRP B 2 332 ? 134.417 124.927 119.938 1.00 86.81  ? 332 TRP B C   1 
ATOM   4337 O O   . TRP B 2 332 ? 133.298 124.962 120.458 1.00 89.39  ? 332 TRP B O   1 
ATOM   4338 C CB  . TRP B 2 332 ? 134.428 122.611 119.027 1.00 80.61  ? 332 TRP B CB  1 
ATOM   4339 C CG  . TRP B 2 332 ? 134.146 121.747 117.843 1.00 84.26  ? 332 TRP B CG  1 
ATOM   4340 C CD1 . TRP B 2 332 ? 134.104 122.133 116.539 1.00 86.02  ? 332 TRP B CD1 1 
ATOM   4341 C CD2 . TRP B 2 332 ? 133.850 120.347 117.857 1.00 84.34  ? 332 TRP B CD2 1 
ATOM   4342 N NE1 . TRP B 2 332 ? 133.806 121.060 115.737 1.00 86.93  ? 332 TRP B NE1 1 
ATOM   4343 C CE2 . TRP B 2 332 ? 133.644 119.951 116.524 1.00 81.02  ? 332 TRP B CE2 1 
ATOM   4344 C CE3 . TRP B 2 332 ? 133.740 119.391 118.869 1.00 83.77  ? 332 TRP B CE3 1 
ATOM   4345 C CZ2 . TRP B 2 332 ? 133.336 118.641 116.176 1.00 80.44  ? 332 TRP B CZ2 1 
ATOM   4346 C CZ3 . TRP B 2 332 ? 133.434 118.093 118.522 1.00 83.33  ? 332 TRP B CZ3 1 
ATOM   4347 C CH2 . TRP B 2 332 ? 133.234 117.729 117.188 1.00 85.08  ? 332 TRP B CH2 1 
ATOM   4348 N N   . ASP B 2 333 ? 135.457 125.592 120.437 1.00 80.74  ? 333 ASP B N   1 
ATOM   4349 C CA  . ASP B 2 333 ? 135.340 126.461 121.597 1.00 77.10  ? 333 ASP B CA  1 
ATOM   4350 C C   . ASP B 2 333 ? 134.794 127.834 121.249 1.00 79.00  ? 333 ASP B C   1 
ATOM   4351 O O   . ASP B 2 333 ? 134.971 128.772 122.034 1.00 84.50  ? 333 ASP B O   1 
ATOM   4352 C CB  . ASP B 2 333 ? 136.696 126.603 122.288 1.00 81.02  ? 333 ASP B CB  1 
ATOM   4353 C CG  . ASP B 2 333 ? 137.775 127.095 121.355 1.00 86.16  ? 333 ASP B CG  1 
ATOM   4354 O OD1 . ASP B 2 333 ? 137.489 127.259 120.153 1.00 88.93  ? 333 ASP B OD1 1 
ATOM   4355 O OD2 . ASP B 2 333 ? 138.911 127.317 121.821 1.00 86.38  ? 333 ASP B OD2 1 
ATOM   4356 N N   . SER B 2 334 ? 134.160 127.965 120.084 1.00 73.59  ? 334 SER B N   1 
ATOM   4357 C CA  . SER B 2 334 ? 133.571 129.207 119.600 1.00 75.04  ? 334 SER B CA  1 
ATOM   4358 C C   . SER B 2 334 ? 134.609 130.288 119.341 1.00 80.61  ? 334 SER B C   1 
ATOM   4359 O O   . SER B 2 334 ? 134.282 131.477 119.377 1.00 86.60  ? 334 SER B O   1 
ATOM   4360 C CB  . SER B 2 334 ? 132.503 129.731 120.565 1.00 79.01  ? 334 SER B CB  1 
ATOM   4361 O OG  . SER B 2 334 ? 133.087 130.518 121.586 1.00 89.08  ? 334 SER B OG  1 
ATOM   4362 N N   . PHE B 2 335 ? 135.854 129.907 119.064 1.00 75.26  ? 335 PHE B N   1 
ATOM   4363 C CA  . PHE B 2 335 ? 136.925 130.866 118.843 1.00 75.79  ? 335 PHE B CA  1 
ATOM   4364 C C   . PHE B 2 335 ? 137.658 130.570 117.545 1.00 75.94  ? 335 PHE B C   1 
ATOM   4365 O O   . PHE B 2 335 ? 137.872 129.406 117.181 1.00 85.58  ? 335 PHE B O   1 
ATOM   4366 C CB  . PHE B 2 335 ? 137.931 130.869 120.003 1.00 79.45  ? 335 PHE B CB  1 
ATOM   4367 C CG  . PHE B 2 335 ? 137.364 131.366 121.298 1.00 76.73  ? 335 PHE B CG  1 
ATOM   4368 C CD1 . PHE B 2 335 ? 136.438 132.391 121.316 1.00 78.48  ? 335 PHE B CD1 1 
ATOM   4369 C CD2 . PHE B 2 335 ? 137.758 130.808 122.498 1.00 75.48  ? 335 PHE B CD2 1 
ATOM   4370 C CE1 . PHE B 2 335 ? 135.914 132.847 122.503 1.00 77.60  ? 335 PHE B CE1 1 
ATOM   4371 C CE2 . PHE B 2 335 ? 137.237 131.260 123.689 1.00 80.79  ? 335 PHE B CE2 1 
ATOM   4372 C CZ  . PHE B 2 335 ? 136.314 132.282 123.691 1.00 80.40  ? 335 PHE B CZ  1 
ATOM   4373 N N   . LEU B 2 336 ? 138.048 131.642 116.865 1.00 71.45  ? 336 LEU B N   1 
ATOM   4374 C CA  . LEU B 2 336 ? 138.939 131.595 115.718 1.00 70.60  ? 336 LEU B CA  1 
ATOM   4375 C C   . LEU B 2 336 ? 140.226 132.309 116.091 1.00 72.44  ? 336 LEU B C   1 
ATOM   4376 O O   . LEU B 2 336 ? 140.191 133.444 116.575 1.00 78.86  ? 336 LEU B O   1 
ATOM   4377 C CB  . LEU B 2 336 ? 138.309 132.273 114.504 1.00 71.66  ? 336 LEU B CB  1 
ATOM   4378 C CG  . LEU B 2 336 ? 137.189 131.538 113.788 1.00 76.68  ? 336 LEU B CG  1 
ATOM   4379 C CD1 . LEU B 2 336 ? 136.023 132.482 113.674 1.00 76.81  ? 336 LEU B CD1 1 
ATOM   4380 C CD2 . LEU B 2 336 ? 137.643 131.079 112.422 1.00 75.78  ? 336 LEU B CD2 1 
ATOM   4381 N N   . LYS B 2 337 ? 141.354 131.652 115.868 1.00 69.45  ? 337 LYS B N   1 
ATOM   4382 C CA  . LYS B 2 337 ? 142.655 132.220 116.175 1.00 71.67  ? 337 LYS B CA  1 
ATOM   4383 C C   . LYS B 2 337 ? 143.447 132.372 114.888 1.00 75.48  ? 337 LYS B C   1 
ATOM   4384 O O   . LYS B 2 337 ? 143.577 131.417 114.117 1.00 86.15  ? 337 LYS B O   1 
ATOM   4385 C CB  . LYS B 2 337 ? 143.410 131.349 117.179 1.00 75.42  ? 337 LYS B CB  1 
ATOM   4386 C CG  . LYS B 2 337 ? 142.818 131.398 118.573 1.00 79.00  ? 337 LYS B CG  1 
ATOM   4387 C CD  . LYS B 2 337 ? 143.736 130.773 119.599 1.00 75.80  ? 337 LYS B CD  1 
ATOM   4388 C CE  . LYS B 2 337 ? 143.244 131.067 121.001 1.00 74.62  ? 337 LYS B CE  1 
ATOM   4389 N NZ  . LYS B 2 337 ? 143.047 132.525 121.220 1.00 80.03  ? 337 LYS B NZ  1 
ATOM   4390 N N   . ILE B 2 338 ? 143.954 133.574 114.651 1.00 68.43  ? 338 ILE B N   1 
ATOM   4391 C CA  . ILE B 2 338 ? 144.826 133.833 113.515 1.00 61.33  ? 338 ILE B CA  1 
ATOM   4392 C C   . ILE B 2 338 ? 146.261 133.725 114.000 1.00 67.51  ? 338 ILE B C   1 
ATOM   4393 O O   . ILE B 2 338 ? 146.689 134.487 114.872 1.00 80.79  ? 338 ILE B O   1 
ATOM   4394 C CB  . ILE B 2 338 ? 144.549 135.211 112.902 1.00 68.00  ? 338 ILE B CB  1 
ATOM   4395 C CG1 . ILE B 2 338 ? 143.130 135.261 112.345 1.00 74.54  ? 338 ILE B CG1 1 
ATOM   4396 C CG2 . ILE B 2 338 ? 145.560 135.516 111.820 1.00 72.75  ? 338 ILE B CG2 1 
ATOM   4397 C CD1 . ILE B 2 338 ? 142.501 136.619 112.445 1.00 76.68  ? 338 ILE B CD1 1 
ATOM   4398 N N   . TRP B 2 339 ? 146.999 132.779 113.438 1.00 72.99  ? 339 TRP B N   1 
ATOM   4399 C CA  . TRP B 2 339 ? 148.351 132.463 113.857 1.00 75.24  ? 339 TRP B CA  1 
ATOM   4400 C C   . TRP B 2 339 ? 149.335 132.998 112.832 1.00 79.47  ? 339 TRP B C   1 
ATOM   4401 O O   . TRP B 2 339 ? 149.060 132.985 111.626 1.00 86.48  ? 339 TRP B O   1 
ATOM   4402 C CB  . TRP B 2 339 ? 148.541 130.955 114.012 1.00 78.77  ? 339 TRP B CB  1 
ATOM   4403 C CG  . TRP B 2 339 ? 147.559 130.322 114.933 1.00 80.19  ? 339 TRP B CG  1 
ATOM   4404 C CD1 . TRP B 2 339 ? 146.257 130.031 114.667 1.00 79.38  ? 339 TRP B CD1 1 
ATOM   4405 C CD2 . TRP B 2 339 ? 147.799 129.900 116.277 1.00 79.75  ? 339 TRP B CD2 1 
ATOM   4406 N NE1 . TRP B 2 339 ? 145.668 129.453 115.761 1.00 75.69  ? 339 TRP B NE1 1 
ATOM   4407 C CE2 . TRP B 2 339 ? 146.595 129.361 116.764 1.00 77.99  ? 339 TRP B CE2 1 
ATOM   4408 C CE3 . TRP B 2 339 ? 148.915 129.925 117.115 1.00 82.95  ? 339 TRP B CE3 1 
ATOM   4409 C CZ2 . TRP B 2 339 ? 146.475 128.853 118.051 1.00 83.97  ? 339 TRP B CZ2 1 
ATOM   4410 C CZ3 . TRP B 2 339 ? 148.795 129.420 118.390 1.00 84.99  ? 339 TRP B CZ3 1 
ATOM   4411 C CH2 . TRP B 2 339 ? 147.584 128.891 118.848 1.00 86.17  ? 339 TRP B CH2 1 
ATOM   4412 N N   . ASN B 2 340 ? 150.478 133.466 113.321 1.00 79.53  ? 340 ASN B N   1 
ATOM   4413 C CA  . ASN B 2 340 ? 151.521 133.957 112.436 1.00 71.01  ? 340 ASN B CA  1 
ATOM   4414 C C   . ASN B 2 340 ? 152.878 133.738 113.085 1.00 78.31  ? 340 ASN B C   1 
ATOM   4415 O O   . ASN B 2 340 ? 152.989 133.565 114.302 1.00 91.22  ? 340 ASN B O   1 
ATOM   4416 C CB  . ASN B 2 340 ? 151.319 135.434 112.095 1.00 74.77  ? 340 ASN B CB  1 
ATOM   4417 C CG  . ASN B 2 340 ? 152.012 135.830 110.814 1.00 80.19  ? 340 ASN B CG  1 
ATOM   4418 O OD1 . ASN B 2 340 ? 152.843 135.089 110.293 1.00 79.95  ? 340 ASN B OD1 1 
ATOM   4419 N ND2 . ASN B 2 340 ? 151.672 137.001 110.294 1.00 82.18  ? 340 ASN B ND2 1 
ATOM   4420 N N   . GLY B 2 341 ? 153.912 133.734 112.251 1.00 81.60  ? 341 GLY B N   1 
ATOM   4421 C CA  . GLY B 2 341 ? 155.258 133.580 112.750 1.00 87.29  ? 341 GLY B CA  1 
ATOM   4422 C C   . GLY B 2 341 ? 155.827 134.872 113.303 1.00 91.44  ? 341 GLY B C   1 
ATOM   4423 O O   . GLY B 2 341 ? 155.298 135.962 113.094 1.00 92.19  ? 341 GLY B O   1 
ATOM   4424 N N   . SER B 2 342 ? 156.930 134.736 114.031 1.00 98.72  ? 342 SER B N   1 
ATOM   4425 C CA  . SER B 2 342 ? 157.653 135.869 114.588 1.00 98.25  ? 342 SER B CA  1 
ATOM   4426 C C   . SER B 2 342 ? 159.105 135.790 114.145 1.00 99.90  ? 342 SER B C   1 
ATOM   4427 O O   . SER B 2 342 ? 159.743 134.741 114.283 1.00 99.31  ? 342 SER B O   1 
ATOM   4428 C CB  . SER B 2 342 ? 157.560 135.887 116.116 1.00 99.58  ? 342 SER B CB  1 
ATOM   4429 O OG  . SER B 2 342 ? 158.269 136.989 116.656 1.00 103.28 ? 342 SER B OG  1 
ATOM   4430 N N   . SER B 2 343 ? 159.622 136.894 113.618 1.00 97.17  ? 343 SER B N   1 
ATOM   4431 C CA  . SER B 2 343 ? 160.990 136.930 113.121 1.00 97.35  ? 343 SER B CA  1 
ATOM   4432 C C   . SER B 2 343 ? 161.993 136.836 114.263 1.00 95.97  ? 343 SER B C   1 
ATOM   4433 O O   . SER B 2 343 ? 162.918 136.026 114.222 1.00 96.25  ? 343 SER B O   1 
ATOM   4434 C CB  . SER B 2 343 ? 161.232 138.204 112.312 1.00 98.96  ? 343 SER B CB  1 
ATOM   4435 O OG  . SER B 2 343 ? 162.507 138.179 111.695 1.00 97.88  ? 343 SER B OG  1 
ATOM   4436 N N   . THR C 3 6   ? 118.773 93.256  86.703  1.00 214.36 ? 6   THR G N   1 
ATOM   4437 C CA  . THR C 3 6   ? 120.065 93.471  86.061  1.00 215.59 ? 6   THR G CA  1 
ATOM   4438 C C   . THR C 3 6   ? 120.757 94.710  86.621  1.00 217.49 ? 6   THR G C   1 
ATOM   4439 O O   . THR C 3 6   ? 121.711 95.218  86.031  1.00 219.05 ? 6   THR G O   1 
ATOM   4440 C CB  . THR C 3 6   ? 119.919 93.619  84.534  1.00 215.13 ? 6   THR G CB  1 
ATOM   4441 O OG1 . THR C 3 6   ? 121.209 93.831  83.946  1.00 215.33 ? 6   THR G OG1 1 
ATOM   4442 C CG2 . THR C 3 6   ? 119.011 94.791  84.195  1.00 214.62 ? 6   THR G CG2 1 
ATOM   4443 N N   . ALA C 3 7   ? 120.264 95.193  87.764  1.00 217.90 ? 7   ALA G N   1 
ATOM   4444 C CA  . ALA C 3 7   ? 120.875 96.355  88.401  1.00 216.81 ? 7   ALA G CA  1 
ATOM   4445 C C   . ALA C 3 7   ? 122.307 96.061  88.828  1.00 217.73 ? 7   ALA G C   1 
ATOM   4446 O O   . ALA C 3 7   ? 123.199 96.903  88.663  1.00 217.76 ? 7   ALA G O   1 
ATOM   4447 C CB  . ALA C 3 7   ? 120.037 96.800  89.600  1.00 215.15 ? 7   ALA G CB  1 
ATOM   4448 N N   . SER C 3 8   ? 122.546 94.870  89.381  1.00 214.97 ? 8   SER G N   1 
ATOM   4449 C CA  . SER C 3 8   ? 123.903 94.482  89.750  1.00 213.42 ? 8   SER G CA  1 
ATOM   4450 C C   . SER C 3 8   ? 124.801 94.414  88.521  1.00 213.89 ? 8   SER G C   1 
ATOM   4451 O O   . SER C 3 8   ? 125.952 94.864  88.553  1.00 212.45 ? 8   SER G O   1 
ATOM   4452 C CB  . SER C 3 8   ? 123.885 93.140  90.482  1.00 211.68 ? 8   SER G CB  1 
ATOM   4453 O OG  . SER C 3 8   ? 123.460 92.096  89.623  1.00 211.74 ? 8   SER G OG  1 
ATOM   4454 N N   . ILE C 3 9   ? 124.283 93.858  87.423  1.00 207.95 ? 9   ILE G N   1 
ATOM   4455 C CA  . ILE C 3 9   ? 125.059 93.779  86.188  1.00 205.83 ? 9   ILE G CA  1 
ATOM   4456 C C   . ILE C 3 9   ? 125.381 95.177  85.674  1.00 204.35 ? 9   ILE G C   1 
ATOM   4457 O O   . ILE C 3 9   ? 126.512 95.456  85.261  1.00 201.54 ? 9   ILE G O   1 
ATOM   4458 C CB  . ILE C 3 9   ? 124.307 92.942  85.134  1.00 203.66 ? 9   ILE G CB  1 
ATOM   4459 C CG1 . ILE C 3 9   ? 124.720 91.469  85.212  1.00 202.42 ? 9   ILE G CG1 1 
ATOM   4460 C CG2 . ILE C 3 9   ? 124.555 93.477  83.728  1.00 201.62 ? 9   ILE G CG2 1 
ATOM   4461 C CD1 . ILE C 3 9   ? 124.288 90.767  86.481  1.00 201.66 ? 9   ILE G CD1 1 
ATOM   4462 N N   . ALA C 3 10  ? 124.396 96.079  85.698  1.00 192.63 ? 10  ALA G N   1 
ATOM   4463 C CA  . ALA C 3 10  ? 124.620 97.437  85.210  1.00 188.56 ? 10  ALA G CA  1 
ATOM   4464 C C   . ALA C 3 10  ? 125.656 98.165  86.058  1.00 185.68 ? 10  ALA G C   1 
ATOM   4465 O O   . ALA C 3 10  ? 126.551 98.836  85.529  1.00 184.52 ? 10  ALA G O   1 
ATOM   4466 C CB  . ALA C 3 10  ? 123.300 98.208  85.189  1.00 187.78 ? 10  ALA G CB  1 
ATOM   4467 N N   . GLN C 3 11  ? 125.549 98.048  87.383  1.00 165.16 ? 11  GLN G N   1 
ATOM   4468 C CA  . GLN C 3 11  ? 126.515 98.692  88.262  1.00 162.52 ? 11  GLN G CA  1 
ATOM   4469 C C   . GLN C 3 11  ? 127.911 98.111  88.106  1.00 161.78 ? 11  GLN G C   1 
ATOM   4470 O O   . GLN C 3 11  ? 128.887 98.870  88.095  1.00 161.77 ? 11  GLN G O   1 
ATOM   4471 C CB  . GLN C 3 11  ? 126.060 98.585  89.720  1.00 164.33 ? 11  GLN G CB  1 
ATOM   4472 C CG  . GLN C 3 11  ? 127.194 98.452  90.724  1.00 165.73 ? 11  GLN G CG  1 
ATOM   4473 C CD  . GLN C 3 11  ? 126.798 98.908  92.114  1.00 166.43 ? 11  GLN G CD  1 
ATOM   4474 O OE1 . GLN C 3 11  ? 126.518 100.086 92.336  1.00 165.84 ? 11  GLN G OE1 1 
ATOM   4475 N NE2 . GLN C 3 11  ? 126.775 97.975  93.059  1.00 165.94 ? 11  GLN G NE2 1 
ATOM   4476 N N   . ALA C 3 12  ? 128.028 96.789  87.962  1.00 161.66 ? 12  ALA G N   1 
ATOM   4477 C CA  . ALA C 3 12  ? 129.332 96.186  87.721  1.00 164.22 ? 12  ALA G CA  1 
ATOM   4478 C C   . ALA C 3 12  ? 129.908 96.642  86.389  1.00 163.78 ? 12  ALA G C   1 
ATOM   4479 O O   . ALA C 3 12  ? 131.117 96.861  86.271  1.00 164.70 ? 12  ALA G O   1 
ATOM   4480 C CB  . ALA C 3 12  ? 129.225 94.663  87.772  1.00 164.31 ? 12  ALA G CB  1 
ATOM   4481 N N   . ARG C 3 13  ? 129.060 96.785  85.368  1.00 157.47 ? 13  ARG G N   1 
ATOM   4482 C CA  . ARG C 3 13  ? 129.534 97.272  84.078  1.00 156.67 ? 13  ARG G CA  1 
ATOM   4483 C C   . ARG C 3 13  ? 130.034 98.708  84.179  1.00 156.33 ? 13  ARG G C   1 
ATOM   4484 O O   . ARG C 3 13  ? 131.076 99.049  83.609  1.00 156.67 ? 13  ARG G O   1 
ATOM   4485 C CB  . ARG C 3 13  ? 128.421 97.157  83.037  1.00 157.54 ? 13  ARG G CB  1 
ATOM   4486 C CG  . ARG C 3 13  ? 128.798 97.674  81.662  1.00 158.81 ? 13  ARG G CG  1 
ATOM   4487 C CD  . ARG C 3 13  ? 128.868 96.548  80.642  1.00 159.60 ? 13  ARG G CD  1 
ATOM   4488 N NE  . ARG C 3 13  ? 127.827 95.549  80.851  1.00 161.68 ? 13  ARG G NE  1 
ATOM   4489 C CZ  . ARG C 3 13  ? 126.564 95.689  80.471  1.00 161.41 ? 13  ARG G CZ  1 
ATOM   4490 N NH1 . ARG C 3 13  ? 126.145 96.781  79.854  1.00 160.72 ? 13  ARG G NH1 1 
ATOM   4491 N NH2 . ARG C 3 13  ? 125.700 94.708  80.716  1.00 159.66 ? 13  ARG G NH2 1 
ATOM   4492 N N   . LYS C 3 14  ? 129.305 99.561  84.901  1.00 147.95 ? 14  LYS G N   1 
ATOM   4493 C CA  . LYS C 3 14  ? 129.760 100.935 85.096  1.00 147.53 ? 14  LYS G CA  1 
ATOM   4494 C C   . LYS C 3 14  ? 131.080 100.961 85.857  1.00 145.77 ? 14  LYS G C   1 
ATOM   4495 O O   . LYS C 3 14  ? 131.978 101.745 85.536  1.00 148.72 ? 14  LYS G O   1 
ATOM   4496 C CB  . LYS C 3 14  ? 128.668 101.744 85.810  1.00 148.91 ? 14  LYS G CB  1 
ATOM   4497 C CG  . LYS C 3 14  ? 129.054 103.124 86.372  1.00 146.80 ? 14  LYS G CG  1 
ATOM   4498 C CD  . LYS C 3 14  ? 129.743 103.072 87.737  1.00 149.15 ? 14  LYS G CD  1 
ATOM   4499 C CE  . LYS C 3 14  ? 128.934 102.257 88.734  1.00 150.42 ? 14  LYS G CE  1 
ATOM   4500 N NZ  . LYS C 3 14  ? 129.671 102.041 90.011  1.00 147.79 ? 14  LYS G NZ  1 
ATOM   4501 N N   . LEU C 3 15  ? 131.210 100.102 86.867  1.00 134.05 ? 15  LEU G N   1 
ATOM   4502 C CA  . LEU C 3 15  ? 132.456 99.980  87.618  1.00 133.51 ? 15  LEU G CA  1 
ATOM   4503 C C   . LEU C 3 15  ? 133.607 99.552  86.709  1.00 132.51 ? 15  LEU G C   1 
ATOM   4504 O O   . LEU C 3 15  ? 134.719 100.101 86.783  1.00 132.51 ? 15  LEU G O   1 
ATOM   4505 C CB  . LEU C 3 15  ? 132.212 98.988  88.761  1.00 136.22 ? 15  LEU G CB  1 
ATOM   4506 C CG  . LEU C 3 15  ? 133.028 98.709  90.025  1.00 136.38 ? 15  LEU G CG  1 
ATOM   4507 C CD1 . LEU C 3 15  ? 134.414 98.215  89.729  1.00 136.16 ? 15  LEU G CD1 1 
ATOM   4508 C CD2 . LEU C 3 15  ? 133.082 99.959  90.889  1.00 134.29 ? 15  LEU G CD2 1 
ATOM   4509 N N   . VAL C 3 16  ? 133.346 98.585  85.828  1.00 139.50 ? 16  VAL G N   1 
ATOM   4510 C CA  . VAL C 3 16  ? 134.367 98.105  84.904  1.00 143.26 ? 16  VAL G CA  1 
ATOM   4511 C C   . VAL C 3 16  ? 134.789 99.215  83.955  1.00 139.69 ? 16  VAL G C   1 
ATOM   4512 O O   . VAL C 3 16  ? 135.981 99.403  83.693  1.00 140.26 ? 16  VAL G O   1 
ATOM   4513 C CB  . VAL C 3 16  ? 133.857 96.868  84.142  1.00 145.92 ? 16  VAL G CB  1 
ATOM   4514 C CG1 . VAL C 3 16  ? 134.716 96.602  82.916  1.00 143.90 ? 16  VAL G CG1 1 
ATOM   4515 C CG2 . VAL C 3 16  ? 133.840 95.657  85.058  1.00 143.99 ? 16  VAL G CG2 1 
ATOM   4516 N N   . GLU C 3 17  ? 133.823 99.966  83.421  1.00 137.87 ? 17  GLU G N   1 
ATOM   4517 C CA  . GLU C 3 17  ? 134.168 101.108 82.580  1.00 139.50 ? 17  GLU G CA  1 
ATOM   4518 C C   . GLU C 3 17  ? 134.965 102.146 83.358  1.00 138.22 ? 17  GLU G C   1 
ATOM   4519 O O   . GLU C 3 17  ? 135.865 102.787 82.805  1.00 137.18 ? 17  GLU G O   1 
ATOM   4520 C CB  . GLU C 3 17  ? 132.913 101.744 81.979  1.00 141.75 ? 17  GLU G CB  1 
ATOM   4521 C CG  . GLU C 3 17  ? 132.186 100.859 80.973  1.00 143.49 ? 17  GLU G CG  1 
ATOM   4522 C CD  . GLU C 3 17  ? 130.909 101.474 80.443  1.00 146.37 ? 17  GLU G CD  1 
ATOM   4523 O OE1 . GLU C 3 17  ? 130.478 102.506 80.989  1.00 148.11 ? 17  GLU G OE1 1 
ATOM   4524 O OE2 . GLU C 3 17  ? 130.339 100.925 79.477  1.00 144.47 ? 17  GLU G OE2 1 
ATOM   4525 N N   . GLN C 3 18  ? 134.648 102.330 84.640  1.00 132.37 ? 18  GLN G N   1 
ATOM   4526 C CA  . GLN C 3 18  ? 135.374 103.306 85.443  1.00 130.56 ? 18  GLN G CA  1 
ATOM   4527 C C   . GLN C 3 18  ? 136.850 102.951 85.540  1.00 129.05 ? 18  GLN G C   1 
ATOM   4528 O O   . GLN C 3 18  ? 137.719 103.777 85.236  1.00 133.81 ? 18  GLN G O   1 
ATOM   4529 C CB  . GLN C 3 18  ? 134.753 103.415 86.834  1.00 132.61 ? 18  GLN G CB  1 
ATOM   4530 C CG  . GLN C 3 18  ? 135.176 104.662 87.587  1.00 130.82 ? 18  GLN G CG  1 
ATOM   4531 C CD  . GLN C 3 18  ? 135.164 105.897 86.712  1.00 133.99 ? 18  GLN G CD  1 
ATOM   4532 O OE1 . GLN C 3 18  ? 134.105 106.401 86.342  1.00 134.07 ? 18  GLN G OE1 1 
ATOM   4533 N NE2 . GLN C 3 18  ? 136.349 106.394 86.376  1.00 136.55 ? 18  GLN G NE2 1 
ATOM   4534 N N   . LEU C 3 19  ? 137.160 101.718 85.950  1.00 123.35 ? 19  LEU G N   1 
ATOM   4535 C CA  . LEU C 3 19  ? 138.579 101.353 85.988  1.00 126.57 ? 19  LEU G CA  1 
ATOM   4536 C C   . LEU C 3 19  ? 139.198 101.182 84.607  1.00 126.59 ? 19  LEU G C   1 
ATOM   4537 O O   . LEU C 3 19  ? 140.416 101.332 84.477  1.00 127.35 ? 19  LEU G O   1 
ATOM   4538 C CB  . LEU C 3 19  ? 138.850 100.105 86.832  1.00 127.21 ? 19  LEU G CB  1 
ATOM   4539 C CG  . LEU C 3 19  ? 138.516 100.120 88.324  1.00 129.26 ? 19  LEU G CG  1 
ATOM   4540 C CD1 . LEU C 3 19  ? 138.911 101.454 88.942  1.00 129.11 ? 19  LEU G CD1 1 
ATOM   4541 C CD2 . LEU C 3 19  ? 137.087 99.849  88.579  1.00 128.32 ? 19  LEU G CD2 1 
ATOM   4542 N N   . LYS C 3 20  ? 138.411 100.885 83.572  1.00 132.97 ? 20  LYS G N   1 
ATOM   4543 C CA  . LYS C 3 20  ? 138.979 100.858 82.230  1.00 135.93 ? 20  LYS G CA  1 
ATOM   4544 C C   . LYS C 3 20  ? 139.436 102.249 81.812  1.00 134.86 ? 20  LYS G C   1 
ATOM   4545 O O   . LYS C 3 20  ? 140.533 102.413 81.265  1.00 133.95 ? 20  LYS G O   1 
ATOM   4546 C CB  . LYS C 3 20  ? 137.962 100.300 81.233  1.00 137.67 ? 20  LYS G CB  1 
ATOM   4547 C CG  . LYS C 3 20  ? 138.213 100.723 79.793  1.00 138.40 ? 20  LYS G CG  1 
ATOM   4548 C CD  . LYS C 3 20  ? 137.001 100.484 78.908  1.00 136.67 ? 20  LYS G CD  1 
ATOM   4549 C CE  . LYS C 3 20  ? 137.215 101.082 77.525  1.00 135.56 ? 20  LYS G CE  1 
ATOM   4550 N NZ  . LYS C 3 20  ? 136.017 100.940 76.655  1.00 135.20 ? 20  LYS G NZ  1 
ATOM   4551 N N   . MET C 3 21  ? 138.609 103.262 82.073  1.00 138.06 ? 21  MET G N   1 
ATOM   4552 C CA  . MET C 3 21  ? 138.994 104.635 81.777  1.00 138.53 ? 21  MET G CA  1 
ATOM   4553 C C   . MET C 3 21  ? 140.160 105.082 82.648  1.00 135.97 ? 21  MET G C   1 
ATOM   4554 O O   . MET C 3 21  ? 141.076 105.756 82.166  1.00 135.60 ? 21  MET G O   1 
ATOM   4555 C CB  . MET C 3 21  ? 137.798 105.568 81.962  1.00 138.48 ? 21  MET G CB  1 
ATOM   4556 C CG  . MET C 3 21  ? 136.811 105.551 80.805  1.00 139.51 ? 21  MET G CG  1 
ATOM   4557 S SD  . MET C 3 21  ? 137.256 106.631 79.427  1.00 145.00 ? 21  MET G SD  1 
ATOM   4558 C CE  . MET C 3 21  ? 138.367 107.795 80.216  1.00 138.27 ? 21  MET G CE  1 
ATOM   4559 N N   . GLU C 3 22  ? 140.150 104.710 83.929  1.00 131.34 ? 22  GLU G N   1 
ATOM   4560 C CA  . GLU C 3 22  ? 141.181 105.170 84.851  1.00 131.28 ? 22  GLU G CA  1 
ATOM   4561 C C   . GLU C 3 22  ? 142.477 104.377 84.732  1.00 129.89 ? 22  GLU G C   1 
ATOM   4562 O O   . GLU C 3 22  ? 143.491 104.790 85.303  1.00 135.35 ? 22  GLU G O   1 
ATOM   4563 C CB  . GLU C 3 22  ? 140.630 105.141 86.285  1.00 133.22 ? 22  GLU G CB  1 
ATOM   4564 C CG  . GLU C 3 22  ? 140.851 103.869 87.096  1.00 135.79 ? 22  GLU G CG  1 
ATOM   4565 C CD  . GLU C 3 22  ? 142.209 103.799 87.766  1.00 137.76 ? 22  GLU G CD  1 
ATOM   4566 O OE1 . GLU C 3 22  ? 142.849 104.858 87.932  1.00 139.50 ? 22  GLU G OE1 1 
ATOM   4567 O OE2 . GLU C 3 22  ? 142.629 102.685 88.140  1.00 137.79 ? 22  GLU G OE2 1 
ATOM   4568 N N   . ALA C 3 23  ? 142.482 103.273 83.987  1.00 112.46 ? 23  ALA G N   1 
ATOM   4569 C CA  . ALA C 3 23  ? 143.717 102.530 83.777  1.00 116.90 ? 23  ALA G CA  1 
ATOM   4570 C C   . ALA C 3 23  ? 144.619 103.204 82.749  1.00 120.68 ? 23  ALA G C   1 
ATOM   4571 O O   . ALA C 3 23  ? 145.848 103.139 82.863  1.00 122.08 ? 23  ALA G O   1 
ATOM   4572 C CB  . ALA C 3 23  ? 143.401 101.098 83.347  1.00 120.77 ? 23  ALA G CB  1 
ATOM   4573 N N   . ASN C 3 24  ? 144.035 103.848 81.740  1.00 128.81 ? 24  ASN G N   1 
ATOM   4574 C CA  . ASN C 3 24  ? 144.805 104.376 80.613  1.00 130.54 ? 24  ASN G CA  1 
ATOM   4575 C C   . ASN C 3 24  ? 145.143 105.855 80.818  1.00 130.64 ? 24  ASN G C   1 
ATOM   4576 O O   . ASN C 3 24  ? 144.790 106.726 80.024  1.00 133.64 ? 24  ASN G O   1 
ATOM   4577 C CB  . ASN C 3 24  ? 144.043 104.156 79.311  1.00 133.71 ? 24  ASN G CB  1 
ATOM   4578 C CG  . ASN C 3 24  ? 144.911 104.367 78.086  1.00 136.46 ? 24  ASN G CG  1 
ATOM   4579 O OD1 . ASN C 3 24  ? 146.123 104.153 78.127  1.00 136.88 ? 24  ASN G OD1 1 
ATOM   4580 N ND2 . ASN C 3 24  ? 144.295 104.786 76.986  1.00 134.86 ? 24  ASN G ND2 1 
ATOM   4581 N N   . ILE C 3 25  ? 145.842 106.129 81.917  1.00 116.86 ? 25  ILE G N   1 
ATOM   4582 C CA  . ILE C 3 25  ? 146.403 107.447 82.198  1.00 117.64 ? 25  ILE G CA  1 
ATOM   4583 C C   . ILE C 3 25  ? 147.916 107.351 82.096  1.00 118.04 ? 25  ILE G C   1 
ATOM   4584 O O   . ILE C 3 25  ? 148.524 106.427 82.648  1.00 117.79 ? 25  ILE G O   1 
ATOM   4585 C CB  . ILE C 3 25  ? 145.989 108.000 83.578  1.00 116.18 ? 25  ILE G CB  1 
ATOM   4586 C CG1 . ILE C 3 25  ? 144.499 108.368 83.665  1.00 119.02 ? 25  ILE G CG1 1 
ATOM   4587 C CG2 . ILE C 3 25  ? 146.837 109.211 83.947  1.00 118.70 ? 25  ILE G CG2 1 
ATOM   4588 C CD1 . ILE C 3 25  ? 143.508 107.306 83.350  1.00 122.13 ? 25  ILE G CD1 1 
ATOM   4589 N N   . ASP C 3 26  ? 148.518 108.296 81.378  1.00 127.32 ? 26  ASP G N   1 
ATOM   4590 C CA  . ASP C 3 26  ? 149.968 108.379 81.335  1.00 126.46 ? 26  ASP G CA  1 
ATOM   4591 C C   . ASP C 3 26  ? 150.505 108.630 82.736  1.00 126.23 ? 26  ASP G C   1 
ATOM   4592 O O   . ASP C 3 26  ? 150.134 109.607 83.392  1.00 129.18 ? 26  ASP G O   1 
ATOM   4593 C CB  . ASP C 3 26  ? 150.407 109.498 80.392  1.00 129.78 ? 26  ASP G CB  1 
ATOM   4594 C CG  . ASP C 3 26  ? 150.158 109.165 78.935  1.00 134.04 ? 26  ASP G CG  1 
ATOM   4595 O OD1 . ASP C 3 26  ? 149.915 107.979 78.626  1.00 135.39 ? 26  ASP G OD1 1 
ATOM   4596 O OD2 . ASP C 3 26  ? 150.196 110.091 78.097  1.00 134.43 ? 26  ASP G OD2 1 
ATOM   4597 N N   . ARG C 3 27  ? 151.374 107.739 83.197  1.00 100.27 ? 27  ARG G N   1 
ATOM   4598 C CA  . ARG C 3 27  ? 151.954 107.826 84.527  1.00 95.51  ? 27  ARG G CA  1 
ATOM   4599 C C   . ARG C 3 27  ? 153.440 108.116 84.409  1.00 100.97 ? 27  ARG G C   1 
ATOM   4600 O O   . ARG C 3 27  ? 154.122 107.570 83.536  1.00 107.62 ? 27  ARG G O   1 
ATOM   4601 C CB  . ARG C 3 27  ? 151.744 106.532 85.308  1.00 99.81  ? 27  ARG G CB  1 
ATOM   4602 C CG  . ARG C 3 27  ? 150.322 106.015 85.301  1.00 105.33 ? 27  ARG G CG  1 
ATOM   4603 C CD  . ARG C 3 27  ? 149.623 106.291 86.618  1.00 104.66 ? 27  ARG G CD  1 
ATOM   4604 N NE  . ARG C 3 27  ? 148.195 106.003 86.550  1.00 102.75 ? 27  ARG G NE  1 
ATOM   4605 C CZ  . ARG C 3 27  ? 147.677 104.787 86.445  1.00 99.97  ? 27  ARG G CZ  1 
ATOM   4606 N NH1 . ARG C 3 27  ? 148.442 103.708 86.416  1.00 101.51 ? 27  ARG G NH1 1 
ATOM   4607 N NH2 . ARG C 3 27  ? 146.356 104.649 86.379  1.00 107.08 ? 27  ARG G NH2 1 
ATOM   4608 N N   . ILE C 3 28  ? 153.939 108.974 85.289  1.00 90.52  ? 28  ILE G N   1 
ATOM   4609 C CA  . ILE C 3 28  ? 155.357 109.282 85.343  1.00 93.31  ? 28  ILE G CA  1 
ATOM   4610 C C   . ILE C 3 28  ? 155.975 108.617 86.566  1.00 97.65  ? 28  ILE G C   1 
ATOM   4611 O O   . ILE C 3 28  ? 155.282 108.184 87.491  1.00 105.39 ? 28  ILE G O   1 
ATOM   4612 C CB  . ILE C 3 28  ? 155.618 110.808 85.308  1.00 92.71  ? 28  ILE G CB  1 
ATOM   4613 C CG1 . ILE C 3 28  ? 155.212 111.467 83.974  1.00 93.16  ? 28  ILE G CG1 1 
ATOM   4614 C CG2 . ILE C 3 28  ? 157.080 111.099 85.609  1.00 96.22  ? 28  ILE G CG2 1 
ATOM   4615 C CD1 . ILE C 3 28  ? 155.181 112.981 83.910  1.00 89.59  ? 28  ILE G CD1 1 
ATOM   4616 N N   . LYS C 3 29  ? 157.299 108.511 86.549  1.00 93.42  ? 29  LYS G N   1 
ATOM   4617 C CA  . LYS C 3 29  ? 158.007 107.957 87.692  1.00 93.20  ? 29  LYS G CA  1 
ATOM   4618 C C   . LYS C 3 29  ? 157.849 108.874 88.896  1.00 94.52  ? 29  LYS G C   1 
ATOM   4619 O O   . LYS C 3 29  ? 157.896 110.101 88.773  1.00 96.37  ? 29  LYS G O   1 
ATOM   4620 C CB  . LYS C 3 29  ? 159.485 107.762 87.364  1.00 93.17  ? 29  LYS G CB  1 
ATOM   4621 C CG  . LYS C 3 29  ? 159.739 106.987 86.084  1.00 90.52  ? 29  LYS G CG  1 
ATOM   4622 C CD  . LYS C 3 29  ? 160.405 105.655 86.376  1.00 90.92  ? 29  LYS G CD  1 
ATOM   4623 C CE  . LYS C 3 29  ? 160.109 104.640 85.286  1.00 95.02  ? 29  LYS G CE  1 
ATOM   4624 N NZ  . LYS C 3 29  ? 158.671 104.261 85.262  1.00 96.88  ? 29  LYS G NZ  1 
ATOM   4625 N N   . VAL C 3 30  ? 157.654 108.268 90.069  1.00 88.39  ? 30  VAL G N   1 
ATOM   4626 C CA  . VAL C 3 30  ? 157.451 109.049 91.285  1.00 83.68  ? 30  VAL G CA  1 
ATOM   4627 C C   . VAL C 3 30  ? 158.672 109.905 91.587  1.00 84.41  ? 30  VAL G C   1 
ATOM   4628 O O   . VAL C 3 30  ? 158.556 110.962 92.214  1.00 85.68  ? 30  VAL G O   1 
ATOM   4629 C CB  . VAL C 3 30  ? 157.081 108.112 92.454  1.00 86.96  ? 30  VAL G CB  1 
ATOM   4630 C CG1 . VAL C 3 30  ? 156.979 108.862 93.767  1.00 85.33  ? 30  VAL G CG1 1 
ATOM   4631 C CG2 . VAL C 3 30  ? 155.768 107.431 92.164  1.00 86.66  ? 30  VAL G CG2 1 
ATOM   4632 N N   . SER C 3 31  ? 159.851 109.490 91.124  1.00 88.59  ? 31  SER G N   1 
ATOM   4633 C CA  . SER C 3 31  ? 161.041 110.312 91.312  1.00 84.42  ? 31  SER G CA  1 
ATOM   4634 C C   . SER C 3 31  ? 160.880 111.670 90.639  1.00 81.85  ? 31  SER G C   1 
ATOM   4635 O O   . SER C 3 31  ? 161.179 112.710 91.235  1.00 90.16  ? 31  SER G O   1 
ATOM   4636 C CB  . SER C 3 31  ? 162.272 109.586 90.771  1.00 84.34  ? 31  SER G CB  1 
ATOM   4637 O OG  . SER C 3 31  ? 162.553 108.425 91.531  1.00 87.75  ? 31  SER G OG  1 
ATOM   4638 N N   . LYS C 3 32  ? 160.394 111.679 89.396  1.00 90.72  ? 32  LYS G N   1 
ATOM   4639 C CA  . LYS C 3 32  ? 160.220 112.940 88.681  1.00 103.01 ? 32  LYS G CA  1 
ATOM   4640 C C   . LYS C 3 32  ? 159.155 113.812 89.336  1.00 106.49 ? 32  LYS G C   1 
ATOM   4641 O O   . LYS C 3 32  ? 159.334 115.029 89.463  1.00 110.41 ? 32  LYS G O   1 
ATOM   4642 C CB  . LYS C 3 32  ? 159.869 112.671 87.219  1.00 102.50 ? 32  LYS G CB  1 
ATOM   4643 C CG  . LYS C 3 32  ? 159.655 113.929 86.396  1.00 99.14  ? 32  LYS G CG  1 
ATOM   4644 C CD  . LYS C 3 32  ? 159.269 113.593 84.967  1.00 104.39 ? 32  LYS G CD  1 
ATOM   4645 C CE  . LYS C 3 32  ? 158.907 114.844 84.187  1.00 105.93 ? 32  LYS G CE  1 
ATOM   4646 N NZ  . LYS C 3 32  ? 158.461 114.526 82.802  1.00 105.02 ? 32  LYS G NZ  1 
ATOM   4647 N N   . ALA C 3 33  ? 158.038 113.211 89.752  1.00 93.09  ? 33  ALA G N   1 
ATOM   4648 C CA  . ALA C 3 33  ? 156.985 113.984 90.402  1.00 87.78  ? 33  ALA G CA  1 
ATOM   4649 C C   . ALA C 3 33  ? 157.456 114.551 91.734  1.00 86.68  ? 33  ALA G C   1 
ATOM   4650 O O   . ALA C 3 33  ? 157.129 115.690 92.082  1.00 94.17  ? 33  ALA G O   1 
ATOM   4651 C CB  . ALA C 3 33  ? 155.744 113.118 90.597  1.00 89.29  ? 33  ALA G CB  1 
ATOM   4652 N N   . ALA C 3 34  ? 158.221 113.767 92.492  1.00 86.70  ? 34  ALA G N   1 
ATOM   4653 C CA  . ALA C 3 34  ? 158.781 114.251 93.747  1.00 93.69  ? 34  ALA G CA  1 
ATOM   4654 C C   . ALA C 3 34  ? 159.766 115.385 93.506  1.00 91.05  ? 34  ALA G C   1 
ATOM   4655 O O   . ALA C 3 34  ? 159.798 116.361 94.264  1.00 93.30  ? 34  ALA G O   1 
ATOM   4656 C CB  . ALA C 3 34  ? 159.457 113.099 94.489  1.00 92.23  ? 34  ALA G CB  1 
ATOM   4657 N N   . ALA C 3 35  ? 160.586 115.268 92.461  1.00 93.15  ? 35  ALA G N   1 
ATOM   4658 C CA  . ALA C 3 35  ? 161.504 116.348 92.124  1.00 86.78  ? 35  ALA G CA  1 
ATOM   4659 C C   . ALA C 3 35  ? 160.746 117.614 91.757  1.00 92.03  ? 35  ALA G C   1 
ATOM   4660 O O   . ALA C 3 35  ? 161.131 118.714 92.161  1.00 102.91 ? 35  ALA G O   1 
ATOM   4661 C CB  . ALA C 3 35  ? 162.425 115.920 90.982  1.00 87.91  ? 35  ALA G CB  1 
ATOM   4662 N N   . ASP C 3 36  ? 159.658 117.477 90.996  1.00 94.16  ? 36  ASP G N   1 
ATOM   4663 C CA  . ASP C 3 36  ? 158.851 118.643 90.648  1.00 95.66  ? 36  ASP G CA  1 
ATOM   4664 C C   . ASP C 3 36  ? 158.213 119.262 91.886  1.00 96.03  ? 36  ASP G C   1 
ATOM   4665 O O   . ASP C 3 36  ? 158.174 120.491 92.028  1.00 100.24 ? 36  ASP G O   1 
ATOM   4666 C CB  . ASP C 3 36  ? 157.780 118.253 89.630  1.00 96.17  ? 36  ASP G CB  1 
ATOM   4667 C CG  . ASP C 3 36  ? 157.138 119.456 88.970  1.00 103.34 ? 36  ASP G CG  1 
ATOM   4668 O OD1 . ASP C 3 36  ? 157.662 120.578 89.136  1.00 105.03 ? 36  ASP G OD1 1 
ATOM   4669 O OD2 . ASP C 3 36  ? 156.109 119.280 88.285  1.00 105.10 ? 36  ASP G OD2 1 
ATOM   4670 N N   . LEU C 3 37  ? 157.709 118.425 92.794  1.00 79.85  ? 37  LEU G N   1 
ATOM   4671 C CA  . LEU C 3 37  ? 157.092 118.929 94.015  1.00 79.49  ? 37  LEU G CA  1 
ATOM   4672 C C   . LEU C 3 37  ? 158.103 119.681 94.872  1.00 90.77  ? 37  LEU G C   1 
ATOM   4673 O O   . LEU C 3 37  ? 157.817 120.778 95.369  1.00 97.64  ? 37  LEU G O   1 
ATOM   4674 C CB  . LEU C 3 37  ? 156.484 117.770 94.801  1.00 77.11  ? 37  LEU G CB  1 
ATOM   4675 C CG  . LEU C 3 37  ? 155.199 118.045 95.574  1.00 77.14  ? 37  LEU G CG  1 
ATOM   4676 C CD1 . LEU C 3 37  ? 154.324 118.983 94.779  1.00 80.81  ? 37  LEU G CD1 1 
ATOM   4677 C CD2 . LEU C 3 37  ? 154.468 116.751 95.867  1.00 85.22  ? 37  LEU G CD2 1 
ATOM   4678 N N   . MET C 3 38  ? 159.300 119.114 95.042  1.00 96.44  ? 38  MET G N   1 
ATOM   4679 C CA  . MET C 3 38  ? 160.327 119.776 95.837  1.00 85.47  ? 38  MET G CA  1 
ATOM   4680 C C   . MET C 3 38  ? 160.843 121.033 95.148  1.00 86.69  ? 38  MET G C   1 
ATOM   4681 O O   . MET C 3 38  ? 161.188 122.010 95.822  1.00 97.22  ? 38  MET G O   1 
ATOM   4682 C CB  . MET C 3 38  ? 161.467 118.800 96.135  1.00 84.03  ? 38  MET G CB  1 
ATOM   4683 C CG  . MET C 3 38  ? 162.501 118.668 95.035  1.00 92.77  ? 38  MET G CG  1 
ATOM   4684 S SD  . MET C 3 38  ? 164.172 118.515 95.678  1.00 106.71 ? 38  MET G SD  1 
ATOM   4685 C CE  . MET C 3 38  ? 163.945 117.137 96.794  1.00 94.68  ? 38  MET G CE  1 
ATOM   4686 N N   . ALA C 3 39  ? 160.887 121.038 93.813  1.00 79.45  ? 39  ALA G N   1 
ATOM   4687 C CA  . ALA C 3 39  ? 161.273 122.243 93.093  1.00 80.43  ? 39  ALA G CA  1 
ATOM   4688 C C   . ALA C 3 39  ? 160.255 123.352 93.302  1.00 83.21  ? 39  ALA G C   1 
ATOM   4689 O O   . ALA C 3 39  ? 160.628 124.516 93.476  1.00 91.74  ? 39  ALA G O   1 
ATOM   4690 C CB  . ALA C 3 39  ? 161.440 121.937 91.606  1.00 82.20  ? 39  ALA G CB  1 
ATOM   4691 N N   . TYR C 3 40  ? 158.965 123.013 93.281  1.00 79.59  ? 40  TYR G N   1 
ATOM   4692 C CA  . TYR C 3 40  ? 157.950 124.016 93.582  1.00 72.27  ? 40  TYR G CA  1 
ATOM   4693 C C   . TYR C 3 40  ? 158.080 124.512 95.014  1.00 75.60  ? 40  TYR G C   1 
ATOM   4694 O O   . TYR C 3 40  ? 157.931 125.710 95.279  1.00 92.01  ? 40  TYR G O   1 
ATOM   4695 C CB  . TYR C 3 40  ? 156.550 123.459 93.343  1.00 76.54  ? 40  TYR G CB  1 
ATOM   4696 C CG  . TYR C 3 40  ? 155.473 124.512 93.459  1.00 71.43  ? 40  TYR G CG  1 
ATOM   4697 C CD1 . TYR C 3 40  ? 154.910 124.825 94.686  1.00 74.36  ? 40  TYR G CD1 1 
ATOM   4698 C CD2 . TYR C 3 40  ? 155.027 125.198 92.341  1.00 81.54  ? 40  TYR G CD2 1 
ATOM   4699 C CE1 . TYR C 3 40  ? 153.933 125.789 94.796  1.00 83.18  ? 40  TYR G CE1 1 
ATOM   4700 C CE2 . TYR C 3 40  ? 154.047 126.162 92.442  1.00 84.00  ? 40  TYR G CE2 1 
ATOM   4701 C CZ  . TYR C 3 40  ? 153.505 126.454 93.672  1.00 84.35  ? 40  TYR G CZ  1 
ATOM   4702 O OH  . TYR C 3 40  ? 152.528 127.415 93.779  1.00 84.91  ? 40  TYR G OH  1 
ATOM   4703 N N   . CYS C 3 41  ? 158.344 123.603 95.954  1.00 93.59  ? 41  CYS G N   1 
ATOM   4704 C CA  . CYS C 3 41  ? 158.482 124.011 97.349  1.00 99.97  ? 41  CYS G CA  1 
ATOM   4705 C C   . CYS C 3 41  ? 159.658 124.962 97.537  1.00 100.45 ? 41  CYS G C   1 
ATOM   4706 O O   . CYS C 3 41  ? 159.556 125.946 98.277  1.00 102.51 ? 41  CYS G O   1 
ATOM   4707 C CB  . CYS C 3 41  ? 158.638 122.784 98.245  1.00 105.38 ? 41  CYS G CB  1 
ATOM   4708 S SG  . CYS C 3 41  ? 157.141 121.790 98.403  1.00 126.20 ? 41  CYS G SG  1 
ATOM   4709 N N   . GLU C 3 42  ? 160.781 124.686 96.875  1.00 95.84  ? 42  GLU G N   1 
ATOM   4710 C CA  . GLU C 3 42  ? 161.963 125.522 97.052  1.00 95.56  ? 42  GLU G CA  1 
ATOM   4711 C C   . GLU C 3 42  ? 161.833 126.834 96.286  1.00 96.63  ? 42  GLU G C   1 
ATOM   4712 O O   . GLU C 3 42  ? 162.316 127.872 96.751  1.00 101.68 ? 42  GLU G O   1 
ATOM   4713 C CB  . GLU C 3 42  ? 163.213 124.709 96.667  1.00 93.11  ? 42  GLU G CB  1 
ATOM   4714 C CG  . GLU C 3 42  ? 164.621 125.368 96.696  1.00 95.73  ? 42  GLU G CG  1 
ATOM   4715 C CD  . GLU C 3 42  ? 164.921 126.449 95.651  1.00 105.57 ? 42  GLU G CD  1 
ATOM   4716 O OE1 . GLU C 3 42  ? 164.049 126.857 94.863  1.00 102.63 ? 42  GLU G OE1 1 
ATOM   4717 O OE2 . GLU C 3 42  ? 166.084 126.903 95.624  1.00 111.61 ? 42  GLU G OE2 1 
ATOM   4718 N N   . ALA C 3 43  ? 161.185 126.811 95.119  1.00 83.92  ? 43  ALA G N   1 
ATOM   4719 C CA  . ALA C 3 43  ? 161.109 128.007 94.286  1.00 78.38  ? 43  ALA G CA  1 
ATOM   4720 C C   . ALA C 3 43  ? 160.329 129.120 94.972  1.00 79.35  ? 43  ALA G C   1 
ATOM   4721 O O   . ALA C 3 43  ? 160.715 130.292 94.901  1.00 86.65  ? 43  ALA G O   1 
ATOM   4722 C CB  . ALA C 3 43  ? 160.478 127.665 92.937  1.00 82.92  ? 43  ALA G CB  1 
ATOM   4723 N N   . HIS C 3 44  ? 159.228 128.778 95.637  1.00 88.66  ? 44  HIS G N   1 
ATOM   4724 C CA  . HIS C 3 44  ? 158.415 129.755 96.347  1.00 92.75  ? 44  HIS G CA  1 
ATOM   4725 C C   . HIS C 3 44  ? 158.701 129.769 97.843  1.00 98.53  ? 44  HIS G C   1 
ATOM   4726 O O   . HIS C 3 44  ? 157.882 130.273 98.619  1.00 103.69 ? 44  HIS G O   1 
ATOM   4727 C CB  . HIS C 3 44  ? 156.932 129.489 96.091  1.00 90.37  ? 44  HIS G CB  1 
ATOM   4728 C CG  . HIS C 3 44  ? 156.554 129.541 94.645  1.00 89.76  ? 44  HIS G CG  1 
ATOM   4729 N ND1 . HIS C 3 44  ? 155.388 128.991 94.160  1.00 97.74  ? 44  HIS G ND1 1 
ATOM   4730 C CD2 . HIS C 3 44  ? 157.190 130.076 93.577  1.00 91.19  ? 44  HIS G CD2 1 
ATOM   4731 C CE1 . HIS C 3 44  ? 155.321 129.187 92.855  1.00 98.44  ? 44  HIS G CE1 1 
ATOM   4732 N NE2 . HIS C 3 44  ? 156.402 129.843 92.477  1.00 99.32  ? 44  HIS G NE2 1 
ATOM   4733 N N   . ALA C 3 45  ? 159.843 129.220 98.262  1.00 106.12 ? 45  ALA G N   1 
ATOM   4734 C CA  . ALA C 3 45  ? 160.163 129.172 99.684  1.00 110.27 ? 45  ALA G CA  1 
ATOM   4735 C C   . ALA C 3 45  ? 160.318 130.569 100.268 1.00 104.93 ? 45  ALA G C   1 
ATOM   4736 O O   . ALA C 3 45  ? 159.798 130.858 101.352 1.00 103.55 ? 45  ALA G O   1 
ATOM   4737 C CB  . ALA C 3 45  ? 161.434 128.355 99.909  1.00 106.67 ? 45  ALA G CB  1 
ATOM   4738 N N   . LYS C 3 46  ? 161.026 131.452 99.565  1.00 94.70  ? 46  LYS G N   1 
ATOM   4739 C CA  . LYS C 3 46  ? 161.238 132.799 100.078 1.00 96.37  ? 46  LYS G CA  1 
ATOM   4740 C C   . LYS C 3 46  ? 159.990 133.661 99.970  1.00 95.75  ? 46  LYS G C   1 
ATOM   4741 O O   . LYS C 3 46  ? 159.869 134.650 100.700 1.00 100.99 ? 46  LYS G O   1 
ATOM   4742 C CB  . LYS C 3 46  ? 162.403 133.466 99.341  1.00 94.31  ? 46  LYS G CB  1 
ATOM   4743 C CG  . LYS C 3 46  ? 163.835 133.104 99.807  1.00 97.26  ? 46  LYS G CG  1 
ATOM   4744 C CD  . LYS C 3 46  ? 164.022 132.577 101.248 1.00 99.87  ? 46  LYS G CD  1 
ATOM   4745 C CE  . LYS C 3 46  ? 163.470 133.494 102.349 1.00 101.17 ? 46  LYS G CE  1 
ATOM   4746 N NZ  . LYS C 3 46  ? 164.030 134.870 102.260 1.00 102.17 ? 46  LYS G NZ  1 
ATOM   4747 N N   . GLU C 3 47  ? 159.060 133.311 99.081  1.00 103.84 ? 47  GLU G N   1 
ATOM   4748 C CA  . GLU C 3 47  ? 157.824 134.071 98.965  1.00 106.12 ? 47  GLU G CA  1 
ATOM   4749 C C   . GLU C 3 47  ? 156.872 133.784 100.116 1.00 106.74 ? 47  GLU G C   1 
ATOM   4750 O O   . GLU C 3 47  ? 156.010 134.618 100.409 1.00 112.74 ? 47  GLU G O   1 
ATOM   4751 C CB  . GLU C 3 47  ? 157.190 133.796 97.586  1.00 112.78 ? 47  GLU G CB  1 
ATOM   4752 C CG  . GLU C 3 47  ? 155.744 134.283 97.305  1.00 115.48 ? 47  GLU G CG  1 
ATOM   4753 C CD  . GLU C 3 47  ? 154.627 133.477 97.972  1.00 113.85 ? 47  GLU G CD  1 
ATOM   4754 O OE1 . GLU C 3 47  ? 153.448 133.749 97.661  1.00 110.12 ? 47  GLU G OE1 1 
ATOM   4755 O OE2 . GLU C 3 47  ? 154.905 132.525 98.727  1.00 111.62 ? 47  GLU G OE2 1 
ATOM   4756 N N   . ASP C 3 48  ? 157.015 132.640 100.785 1.00 89.28  ? 48  ASP G N   1 
ATOM   4757 C CA  . ASP C 3 48  ? 156.053 132.220 101.794 1.00 89.94  ? 48  ASP G CA  1 
ATOM   4758 C C   . ASP C 3 48  ? 156.454 132.764 103.158 1.00 91.92  ? 48  ASP G C   1 
ATOM   4759 O O   . ASP C 3 48  ? 157.486 132.342 103.702 1.00 97.33  ? 48  ASP G O   1 
ATOM   4760 C CB  . ASP C 3 48  ? 155.962 130.704 101.841 1.00 101.38 ? 48  ASP G CB  1 
ATOM   4761 C CG  . ASP C 3 48  ? 154.651 130.217 102.419 1.00 109.70 ? 48  ASP G CG  1 
ATOM   4762 O OD1 . ASP C 3 48  ? 154.039 130.956 103.217 1.00 111.90 ? 48  ASP G OD1 1 
ATOM   4763 O OD2 . ASP C 3 48  ? 154.231 129.091 102.077 1.00 99.78  ? 48  ASP G OD2 1 
ATOM   4764 N N   . PRO C 3 49  ? 155.684 133.680 103.751 1.00 92.77  ? 49  PRO G N   1 
ATOM   4765 C CA  . PRO C 3 49  ? 155.992 134.124 105.118 1.00 94.77  ? 49  PRO G CA  1 
ATOM   4766 C C   . PRO C 3 49  ? 155.731 133.066 106.172 1.00 94.15  ? 49  PRO G C   1 
ATOM   4767 O O   . PRO C 3 49  ? 156.226 133.203 107.297 1.00 101.62 ? 49  PRO G O   1 
ATOM   4768 C CB  . PRO C 3 49  ? 155.073 135.339 105.311 1.00 92.08  ? 49  PRO G CB  1 
ATOM   4769 C CG  . PRO C 3 49  ? 154.703 135.759 103.922 1.00 95.75  ? 49  PRO G CG  1 
ATOM   4770 C CD  . PRO C 3 49  ? 154.626 134.494 103.138 1.00 96.19  ? 49  PRO G CD  1 
ATOM   4771 N N   . LEU C 3 50  ? 154.965 132.024 105.849 1.00 86.51  ? 50  LEU G N   1 
ATOM   4772 C CA  . LEU C 3 50  ? 154.701 130.965 106.816 1.00 79.77  ? 50  LEU G CA  1 
ATOM   4773 C C   . LEU C 3 50  ? 155.980 130.214 107.164 1.00 77.05  ? 50  LEU G C   1 
ATOM   4774 O O   . LEU C 3 50  ? 156.307 130.034 108.341 1.00 75.58  ? 50  LEU G O   1 
ATOM   4775 C CB  . LEU C 3 50  ? 153.653 130.004 106.257 1.00 87.33  ? 50  LEU G CB  1 
ATOM   4776 C CG  . LEU C 3 50  ? 152.227 130.053 106.808 1.00 81.25  ? 50  LEU G CG  1 
ATOM   4777 C CD1 . LEU C 3 50  ? 152.230 129.727 108.254 1.00 68.18  ? 50  LEU G CD1 1 
ATOM   4778 C CD2 . LEU C 3 50  ? 151.586 131.399 106.594 1.00 83.76  ? 50  LEU G CD2 1 
ATOM   4779 N N   . LEU C 3 51  ? 156.720 129.769 106.146 1.00 85.39  ? 51  LEU G N   1 
ATOM   4780 C CA  . LEU C 3 51  ? 157.948 129.019 106.388 1.00 82.35  ? 51  LEU G CA  1 
ATOM   4781 C C   . LEU C 3 51  ? 159.063 129.928 106.890 1.00 88.84  ? 51  LEU G C   1 
ATOM   4782 O O   . LEU C 3 51  ? 159.740 129.610 107.875 1.00 97.33  ? 51  LEU G O   1 
ATOM   4783 C CB  . LEU C 3 51  ? 158.373 128.295 105.112 1.00 83.51  ? 51  LEU G CB  1 
ATOM   4784 C CG  . LEU C 3 51  ? 159.836 127.867 105.019 1.00 91.39  ? 51  LEU G CG  1 
ATOM   4785 C CD1 . LEU C 3 51  ? 160.118 126.706 105.951 1.00 95.54  ? 51  LEU G CD1 1 
ATOM   4786 C CD2 . LEU C 3 51  ? 160.187 127.505 103.585 1.00 91.53  ? 51  LEU G CD2 1 
ATOM   4787 N N   . THR C 3 52  ? 159.270 131.062 106.226 1.00 97.52  ? 52  THR G N   1 
ATOM   4788 C CA  . THR C 3 52  ? 160.291 132.023 106.628 1.00 100.28 ? 52  THR G CA  1 
ATOM   4789 C C   . THR C 3 52  ? 159.609 133.251 107.210 1.00 104.96 ? 52  THR G C   1 
ATOM   4790 O O   . THR C 3 52  ? 158.881 133.945 106.484 1.00 113.49 ? 52  THR G O   1 
ATOM   4791 C CB  . THR C 3 52  ? 161.170 132.416 105.441 1.00 101.07 ? 52  THR G CB  1 
ATOM   4792 O OG1 . THR C 3 52  ? 160.587 133.536 104.765 1.00 102.85 ? 52  THR G OG1 1 
ATOM   4793 C CG2 . THR C 3 52  ? 161.298 131.258 104.471 1.00 101.90 ? 52  THR G CG2 1 
ATOM   4794 N N   . PRO C 3 53  ? 159.804 133.557 108.492 1.00 102.06 ? 53  PRO G N   1 
ATOM   4795 C CA  . PRO C 3 53  ? 159.044 134.650 109.112 1.00 102.86 ? 53  PRO G CA  1 
ATOM   4796 C C   . PRO C 3 53  ? 159.285 135.979 108.413 1.00 103.34 ? 53  PRO G C   1 
ATOM   4797 O O   . PRO C 3 53  ? 160.409 136.312 108.033 1.00 104.83 ? 53  PRO G O   1 
ATOM   4798 C CB  . PRO C 3 53  ? 159.551 134.680 110.559 1.00 103.96 ? 53  PRO G CB  1 
ATOM   4799 C CG  . PRO C 3 53  ? 160.534 133.585 110.706 1.00 108.14 ? 53  PRO G CG  1 
ATOM   4800 C CD  . PRO C 3 53  ? 160.737 132.888 109.412 1.00 104.75 ? 53  PRO G CD  1 
ATOM   4801 N N   . VAL C 3 54  ? 158.206 136.736 108.246 1.00 105.70 ? 54  VAL G N   1 
ATOM   4802 C CA  . VAL C 3 54  ? 158.243 138.059 107.629 1.00 105.50 ? 54  VAL G CA  1 
ATOM   4803 C C   . VAL C 3 54  ? 158.782 139.045 108.659 1.00 112.75 ? 54  VAL G C   1 
ATOM   4804 O O   . VAL C 3 54  ? 158.585 138.839 109.866 1.00 117.51 ? 54  VAL G O   1 
ATOM   4805 C CB  . VAL C 3 54  ? 156.846 138.458 107.120 1.00 108.87 ? 54  VAL G CB  1 
ATOM   4806 C CG1 . VAL C 3 54  ? 155.883 138.648 108.282 1.00 110.87 ? 54  VAL G CG1 1 
ATOM   4807 C CG2 . VAL C 3 54  ? 156.902 139.705 106.249 1.00 108.29 ? 54  VAL G CG2 1 
ATOM   4808 N N   . PRO C 3 55  ? 159.491 140.099 108.250 1.00 116.74 ? 55  PRO G N   1 
ATOM   4809 C CA  . PRO C 3 55  ? 159.859 141.145 109.210 1.00 114.25 ? 55  PRO G CA  1 
ATOM   4810 C C   . PRO C 3 55  ? 158.624 141.760 109.850 1.00 115.63 ? 55  PRO G C   1 
ATOM   4811 O O   . PRO C 3 55  ? 157.568 141.881 109.226 1.00 120.65 ? 55  PRO G O   1 
ATOM   4812 C CB  . PRO C 3 55  ? 160.613 142.163 108.350 1.00 111.62 ? 55  PRO G CB  1 
ATOM   4813 C CG  . PRO C 3 55  ? 161.203 141.348 107.260 1.00 113.23 ? 55  PRO G CG  1 
ATOM   4814 C CD  . PRO C 3 55  ? 160.225 140.237 106.980 1.00 114.72 ? 55  PRO G CD  1 
ATOM   4815 N N   . ALA C 3 56  ? 158.772 142.145 111.120 1.00 107.86 ? 56  ALA G N   1 
ATOM   4816 C CA  . ALA C 3 56  ? 157.626 142.606 111.899 1.00 108.46 ? 56  ALA G CA  1 
ATOM   4817 C C   . ALA C 3 56  ? 156.985 143.850 111.298 1.00 112.96 ? 56  ALA G C   1 
ATOM   4818 O O   . ALA C 3 56  ? 155.780 144.068 111.470 1.00 113.46 ? 56  ALA G O   1 
ATOM   4819 C CB  . ALA C 3 56  ? 158.049 142.876 113.342 1.00 105.95 ? 56  ALA G CB  1 
ATOM   4820 N N   . SER C 3 57  ? 157.765 144.680 110.602 1.00 118.63 ? 57  SER G N   1 
ATOM   4821 C CA  . SER C 3 57  ? 157.200 145.882 109.997 1.00 115.48 ? 57  SER G CA  1 
ATOM   4822 C C   . SER C 3 57  ? 156.193 145.534 108.909 1.00 115.62 ? 57  SER G C   1 
ATOM   4823 O O   . SER C 3 57  ? 155.101 146.111 108.856 1.00 115.47 ? 57  SER G O   1 
ATOM   4824 C CB  . SER C 3 57  ? 158.317 146.758 109.431 1.00 117.50 ? 57  SER G CB  1 
ATOM   4825 O OG  . SER C 3 57  ? 158.972 146.112 108.355 1.00 121.15 ? 57  SER G OG  1 
ATOM   4826 N N   . GLU C 3 58  ? 156.537 144.587 108.037 1.00 122.64 ? 58  GLU G N   1 
ATOM   4827 C CA  . GLU C 3 58  ? 155.652 144.189 106.951 1.00 121.66 ? 58  GLU G CA  1 
ATOM   4828 C C   . GLU C 3 58  ? 154.500 143.310 107.415 1.00 121.95 ? 58  GLU G C   1 
ATOM   4829 O O   . GLU C 3 58  ? 153.559 143.094 106.645 1.00 122.25 ? 58  GLU G O   1 
ATOM   4830 C CB  . GLU C 3 58  ? 156.447 143.457 105.867 1.00 122.01 ? 58  GLU G CB  1 
ATOM   4831 C CG  . GLU C 3 58  ? 157.359 144.353 105.044 1.00 125.61 ? 58  GLU G CG  1 
ATOM   4832 C CD  . GLU C 3 58  ? 156.958 145.814 105.103 1.00 131.09 ? 58  GLU G CD  1 
ATOM   4833 O OE1 . GLU C 3 58  ? 155.990 146.195 104.411 1.00 132.63 ? 58  GLU G OE1 1 
ATOM   4834 O OE2 . GLU C 3 58  ? 157.612 146.582 105.840 1.00 132.14 ? 58  GLU G OE2 1 
ATOM   4835 N N   . ASN C 3 59  ? 154.550 142.805 108.636 1.00 107.49 ? 59  ASN G N   1 
ATOM   4836 C CA  . ASN C 3 59  ? 153.502 141.927 109.136 1.00 98.63  ? 59  ASN G CA  1 
ATOM   4837 C C   . ASN C 3 59  ? 152.229 142.722 109.390 1.00 97.37  ? 59  ASN G C   1 
ATOM   4838 O O   . ASN C 3 59  ? 152.257 143.690 110.160 1.00 104.25 ? 59  ASN G O   1 
ATOM   4839 C CB  . ASN C 3 59  ? 153.964 141.243 110.417 1.00 101.47 ? 59  ASN G CB  1 
ATOM   4840 C CG  . ASN C 3 59  ? 153.173 139.993 110.729 1.00 100.34 ? 59  ASN G CG  1 
ATOM   4841 O OD1 . ASN C 3 59  ? 151.943 139.995 110.687 1.00 103.01 ? 59  ASN G OD1 1 
ATOM   4842 N ND2 . ASN C 3 59  ? 153.876 138.916 111.053 1.00 99.13  ? 59  ASN G ND2 1 
ATOM   4843 N N   . PRO C 3 60  ? 151.102 142.360 108.776 1.00 81.17  ? 60  PRO G N   1 
ATOM   4844 C CA  . PRO C 3 60  ? 149.835 143.035 109.065 1.00 90.32  ? 60  PRO G CA  1 
ATOM   4845 C C   . PRO C 3 60  ? 149.099 142.490 110.277 1.00 96.99  ? 60  PRO G C   1 
ATOM   4846 O O   . PRO C 3 60  ? 147.921 142.810 110.458 1.00 103.71 ? 60  PRO G O   1 
ATOM   4847 C CB  . PRO C 3 60  ? 149.026 142.788 107.784 1.00 92.44  ? 60  PRO G CB  1 
ATOM   4848 C CG  . PRO C 3 60  ? 149.583 141.526 107.208 1.00 93.91  ? 60  PRO G CG  1 
ATOM   4849 C CD  . PRO C 3 60  ? 150.943 141.274 107.800 1.00 88.57  ? 60  PRO G CD  1 
ATOM   4850 N N   . PHE C 3 61  ? 149.760 141.681 111.096 1.00 94.69  ? 61  PHE G N   1 
ATOM   4851 C CA  . PHE C 3 61  ? 149.195 141.109 112.311 1.00 95.90  ? 61  PHE G CA  1 
ATOM   4852 C C   . PHE C 3 61  ? 150.104 141.404 113.495 1.00 103.64 ? 61  PHE G C   1 
ATOM   4853 O O   . PHE C 3 61  ? 150.480 140.515 114.263 1.00 108.07 ? 61  PHE G O   1 
ATOM   4854 C CB  . PHE C 3 61  ? 148.967 139.611 112.143 1.00 93.68  ? 61  PHE G CB  1 
ATOM   4855 C CG  . PHE C 3 61  ? 147.808 139.272 111.253 1.00 89.48  ? 61  PHE G CG  1 
ATOM   4856 C CD1 . PHE C 3 61  ? 146.511 139.366 111.719 1.00 93.07  ? 61  PHE G CD1 1 
ATOM   4857 C CD2 . PHE C 3 61  ? 148.015 138.869 109.948 1.00 87.24  ? 61  PHE G CD2 1 
ATOM   4858 C CE1 . PHE C 3 61  ? 145.444 139.056 110.903 1.00 94.97  ? 61  PHE G CE1 1 
ATOM   4859 C CE2 . PHE C 3 61  ? 146.952 138.562 109.128 1.00 84.66  ? 61  PHE G CE2 1 
ATOM   4860 C CZ  . PHE C 3 61  ? 145.667 138.653 109.606 1.00 87.49  ? 61  PHE G CZ  1 
ATOM   4861 N N   . ARG C 3 62  ? 150.484 142.674 113.635 1.00 109.14 ? 62  ARG G N   1 
ATOM   4862 C CA  . ARG C 3 62  ? 151.433 143.128 114.652 1.00 107.11 ? 62  ARG G CA  1 
ATOM   4863 C C   . ARG C 3 62  ? 152.790 142.462 114.464 1.00 111.20 ? 62  ARG G C   1 
ATOM   4864 O O   . ARG C 3 62  ? 153.697 143.043 113.868 1.00 107.23 ? 62  ARG G O   1 
ATOM   4865 C CB  . ARG C 3 62  ? 150.908 142.859 116.065 1.00 109.83 ? 62  ARG G CB  1 
ATOM   4866 C CG  . ARG C 3 62  ? 149.476 143.294 116.299 1.00 109.24 ? 62  ARG G CG  1 
ATOM   4867 C CD  . ARG C 3 62  ? 148.995 142.859 117.677 1.00 108.72 ? 62  ARG G CD  1 
ATOM   4868 N NE  . ARG C 3 62  ? 149.726 143.506 118.761 1.00 108.12 ? 62  ARG G NE  1 
ATOM   4869 C CZ  . ARG C 3 62  ? 149.688 144.803 119.033 1.00 111.56 ? 62  ARG G CZ  1 
ATOM   4870 N NH1 . ARG C 3 62  ? 148.934 145.637 118.335 1.00 110.83 ? 62  ARG G NH1 1 
ATOM   4871 N NH2 . ARG C 3 62  ? 150.418 145.276 120.039 1.00 111.82 ? 62  ARG G NH2 1 
ATOM   4872 N N   . VAL D 4 2   ? 116.006 152.369 95.954  1.00 58.99  ? 2   VAL S N   1 
ATOM   4873 C CA  . VAL D 4 2   ? 116.432 153.119 97.128  1.00 71.64  ? 2   VAL S CA  1 
ATOM   4874 C C   . VAL D 4 2   ? 115.970 154.564 97.021  1.00 73.84  ? 2   VAL S C   1 
ATOM   4875 O O   . VAL D 4 2   ? 116.344 155.271 96.088  1.00 75.36  ? 2   VAL S O   1 
ATOM   4876 C CB  . VAL D 4 2   ? 117.954 153.052 97.307  1.00 67.63  ? 2   VAL S CB  1 
ATOM   4877 C CG1 . VAL D 4 2   ? 118.380 153.909 98.480  1.00 67.11  ? 2   VAL S CG1 1 
ATOM   4878 C CG2 . VAL D 4 2   ? 118.401 151.616 97.501  1.00 70.43  ? 2   VAL S CG2 1 
ATOM   4879 N N   . GLN D 4 3   ? 115.156 155.003 97.976  1.00 83.37  ? 3   GLN S N   1 
ATOM   4880 C CA  . GLN D 4 3   ? 114.616 156.354 97.984  1.00 80.02  ? 3   GLN S CA  1 
ATOM   4881 C C   . GLN D 4 3   ? 114.946 157.047 99.297  1.00 89.06  ? 3   GLN S C   1 
ATOM   4882 O O   . GLN D 4 3   ? 114.847 156.448 100.373 1.00 95.53  ? 3   GLN S O   1 
ATOM   4883 C CB  . GLN D 4 3   ? 113.104 156.351 97.765  1.00 82.84  ? 3   GLN S CB  1 
ATOM   4884 C CG  . GLN D 4 3   ? 112.694 156.228 96.312  1.00 87.92  ? 3   GLN S CG  1 
ATOM   4885 C CD  . GLN D 4 3   ? 111.268 156.674 96.074  1.00 92.82  ? 3   GLN S CD  1 
ATOM   4886 O OE1 . GLN D 4 3   ? 110.587 157.128 96.993  1.00 94.35  ? 3   GLN S OE1 1 
ATOM   4887 N NE2 . GLN D 4 3   ? 110.807 156.550 94.836  1.00 89.87  ? 3   GLN S NE2 1 
ATOM   4888 N N   . LEU D 4 4   ? 115.320 158.319 99.197  1.00 76.52  ? 4   LEU S N   1 
ATOM   4889 C CA  . LEU D 4 4   ? 115.729 159.146 100.325 1.00 66.43  ? 4   LEU S CA  1 
ATOM   4890 C C   . LEU D 4 4   ? 115.033 160.497 100.268 1.00 72.54  ? 4   LEU S C   1 
ATOM   4891 O O   . LEU D 4 4   ? 115.657 161.551 100.398 1.00 80.67  ? 4   LEU S O   1 
ATOM   4892 C CB  . LEU D 4 4   ? 117.242 159.326 100.337 1.00 67.85  ? 4   LEU S CB  1 
ATOM   4893 C CG  . LEU D 4 4   ? 117.976 159.116 101.658 1.00 76.14  ? 4   LEU S CG  1 
ATOM   4894 C CD1 . LEU D 4 4   ? 117.382 157.951 102.403 1.00 78.29  ? 4   LEU S CD1 1 
ATOM   4895 C CD2 . LEU D 4 4   ? 119.455 158.892 101.411 1.00 81.75  ? 4   LEU S CD2 1 
ATOM   4896 N N   . VAL D 4 5   ? 113.713 160.480 100.060 1.00 88.41  ? 5   VAL S N   1 
ATOM   4897 C CA  . VAL D 4 5   ? 112.970 161.727 99.911  1.00 88.40  ? 5   VAL S CA  1 
ATOM   4898 C C   . VAL D 4 5   ? 113.026 162.535 101.208 1.00 91.87  ? 5   VAL S C   1 
ATOM   4899 O O   . VAL D 4 5   ? 113.321 162.016 102.291 1.00 93.56  ? 5   VAL S O   1 
ATOM   4900 C CB  . VAL D 4 5   ? 111.516 161.452 99.497  1.00 91.65  ? 5   VAL S CB  1 
ATOM   4901 C CG1 . VAL D 4 5   ? 110.652 161.179 100.718 1.00 91.35  ? 5   VAL S CG1 1 
ATOM   4902 C CG2 . VAL D 4 5   ? 110.959 162.612 98.684  1.00 89.67  ? 5   VAL S CG2 1 
ATOM   4903 N N   . GLU D 4 6   ? 112.739 163.829 101.088 1.00 92.85  ? 6   GLU S N   1 
ATOM   4904 C CA  . GLU D 4 6   ? 112.805 164.754 102.208 1.00 86.65  ? 6   GLU S CA  1 
ATOM   4905 C C   . GLU D 4 6   ? 111.550 165.612 102.255 1.00 92.80  ? 6   GLU S C   1 
ATOM   4906 O O   . GLU D 4 6   ? 110.835 165.766 101.262 1.00 94.58  ? 6   GLU S O   1 
ATOM   4907 C CB  . GLU D 4 6   ? 114.034 165.660 102.120 1.00 78.42  ? 6   GLU S CB  1 
ATOM   4908 C CG  . GLU D 4 6   ? 115.340 164.955 102.338 1.00 81.57  ? 6   GLU S CG  1 
ATOM   4909 C CD  . GLU D 4 6   ? 116.048 164.651 101.039 1.00 93.44  ? 6   GLU S CD  1 
ATOM   4910 O OE1 . GLU D 4 6   ? 115.363 164.293 100.058 1.00 94.97  ? 6   GLU S OE1 1 
ATOM   4911 O OE2 . GLU D 4 6   ? 117.289 164.781 100.990 1.00 94.31  ? 6   GLU S OE2 1 
ATOM   4912 N N   . SER D 4 7   ? 111.295 166.174 103.434 1.00 95.15  ? 7   SER S N   1 
ATOM   4913 C CA  . SER D 4 7   ? 110.155 167.051 103.638 1.00 93.66  ? 7   SER S CA  1 
ATOM   4914 C C   . SER D 4 7   ? 110.475 168.025 104.761 1.00 94.51  ? 7   SER S C   1 
ATOM   4915 O O   . SER D 4 7   ? 111.373 167.795 105.577 1.00 94.25  ? 7   SER S O   1 
ATOM   4916 C CB  . SER D 4 7   ? 108.882 166.261 103.958 1.00 95.56  ? 7   SER S CB  1 
ATOM   4917 O OG  . SER D 4 7   ? 107.775 167.129 104.128 1.00 100.19 ? 7   SER S OG  1 
ATOM   4918 N N   . GLY D 4 8   ? 109.722 169.120 104.791 1.00 101.96 ? 8   GLY S N   1 
ATOM   4919 C CA  . GLY D 4 8   ? 109.947 170.165 105.768 1.00 104.12 ? 8   GLY S CA  1 
ATOM   4920 C C   . GLY D 4 8   ? 110.938 171.193 105.268 1.00 104.95 ? 8   GLY S C   1 
ATOM   4921 O O   . GLY D 4 8   ? 112.077 170.854 104.942 1.00 109.55 ? 8   GLY S O   1 
ATOM   4922 N N   . GLY D 4 9   ? 110.520 172.443 105.199 1.00 104.74 ? 9   GLY S N   1 
ATOM   4923 C CA  . GLY D 4 9   ? 111.375 173.501 104.711 1.00 104.76 ? 9   GLY S CA  1 
ATOM   4924 C C   . GLY D 4 9   ? 110.543 174.600 104.085 1.00 107.30 ? 9   GLY S C   1 
ATOM   4925 O O   . GLY D 4 9   ? 109.328 174.655 104.247 1.00 107.77 ? 9   GLY S O   1 
ATOM   4926 N N   . GLY D 4 10  ? 111.233 175.482 103.360 1.00 113.30 ? 10  GLY S N   1 
ATOM   4927 C CA  . GLY D 4 10  ? 110.598 176.608 102.710 1.00 111.71 ? 10  GLY S CA  1 
ATOM   4928 C C   . GLY D 4 10  ? 111.050 177.927 103.313 1.00 111.97 ? 10  GLY S C   1 
ATOM   4929 O O   . GLY D 4 10  ? 112.200 178.068 103.747 1.00 112.24 ? 10  GLY S O   1 
ATOM   4930 N N   . LEU D 4 11  ? 110.131 178.888 103.331 1.00 112.76 ? 11  LEU S N   1 
ATOM   4931 C CA  . LEU D 4 11  ? 110.417 180.221 103.847 1.00 111.24 ? 11  LEU S CA  1 
ATOM   4932 C C   . LEU D 4 11  ? 110.212 180.240 105.356 1.00 109.73 ? 11  LEU S C   1 
ATOM   4933 O O   . LEU D 4 11  ? 109.122 179.924 105.843 1.00 112.14 ? 11  LEU S O   1 
ATOM   4934 C CB  . LEU D 4 11  ? 109.516 181.252 103.171 1.00 110.55 ? 11  LEU S CB  1 
ATOM   4935 C CG  . LEU D 4 11  ? 110.067 182.662 102.948 1.00 111.48 ? 11  LEU S CG  1 
ATOM   4936 C CD1 . LEU D 4 11  ? 111.575 182.647 102.776 1.00 111.11 ? 11  LEU S CD1 1 
ATOM   4937 C CD2 . LEU D 4 11  ? 109.396 183.313 101.749 1.00 113.25 ? 11  LEU S CD2 1 
ATOM   4938 N N   . VAL D 4 12  ? 111.256 180.607 106.096 1.00 113.05 ? 12  VAL S N   1 
ATOM   4939 C CA  . VAL D 4 12  ? 111.175 180.726 107.545 1.00 114.80 ? 12  VAL S CA  1 
ATOM   4940 C C   . VAL D 4 12  ? 111.765 182.064 107.968 1.00 120.19 ? 12  VAL S C   1 
ATOM   4941 O O   . VAL D 4 12  ? 112.620 182.635 107.283 1.00 122.53 ? 12  VAL S O   1 
ATOM   4942 C CB  . VAL D 4 12  ? 111.887 179.556 108.261 1.00 114.92 ? 12  VAL S CB  1 
ATOM   4943 C CG1 . VAL D 4 12  ? 113.373 179.832 108.408 1.00 116.56 ? 12  VAL S CG1 1 
ATOM   4944 C CG2 . VAL D 4 12  ? 111.249 179.297 109.617 1.00 116.01 ? 12  VAL S CG2 1 
ATOM   4945 N N   . GLN D 4 13  ? 111.283 182.575 109.099 1.00 122.24 ? 13  GLN S N   1 
ATOM   4946 C CA  . GLN D 4 13  ? 111.817 183.798 109.673 1.00 118.37 ? 13  GLN S CA  1 
ATOM   4947 C C   . GLN D 4 13  ? 113.093 183.499 110.459 1.00 119.84 ? 13  GLN S C   1 
ATOM   4948 O O   . GLN D 4 13  ? 113.241 182.410 111.020 1.00 121.36 ? 13  GLN S O   1 
ATOM   4949 C CB  . GLN D 4 13  ? 110.782 184.452 110.582 1.00 116.77 ? 13  GLN S CB  1 
ATOM   4950 C CG  . GLN D 4 13  ? 109.532 184.915 109.857 1.00 117.48 ? 13  GLN S CG  1 
ATOM   4951 C CD  . GLN D 4 13  ? 108.522 185.553 110.788 1.00 122.88 ? 13  GLN S CD  1 
ATOM   4952 O OE1 . GLN D 4 13  ? 108.753 185.662 111.992 1.00 125.40 ? 13  GLN S OE1 1 
ATOM   4953 N NE2 . GLN D 4 13  ? 107.393 185.980 110.234 1.00 122.13 ? 13  GLN S NE2 1 
ATOM   4954 N N   . PRO D 4 14  ? 114.030 184.444 110.518 1.00 108.46 ? 14  PRO S N   1 
ATOM   4955 C CA  . PRO D 4 14  ? 115.293 184.170 111.209 1.00 109.56 ? 14  PRO S CA  1 
ATOM   4956 C C   . PRO D 4 14  ? 115.099 184.058 112.711 1.00 107.30 ? 14  PRO S C   1 
ATOM   4957 O O   . PRO D 4 14  ? 114.199 184.665 113.296 1.00 108.95 ? 14  PRO S O   1 
ATOM   4958 C CB  . PRO D 4 14  ? 116.176 185.371 110.846 1.00 108.64 ? 14  PRO S CB  1 
ATOM   4959 C CG  . PRO D 4 14  ? 115.272 186.386 110.209 1.00 110.62 ? 14  PRO S CG  1 
ATOM   4960 C CD  . PRO D 4 14  ? 113.870 185.874 110.214 1.00 107.65 ? 14  PRO S CD  1 
ATOM   4961 N N   . GLY D 4 15  ? 115.959 183.257 113.333 1.00 103.48 ? 15  GLY S N   1 
ATOM   4962 C CA  . GLY D 4 15  ? 115.885 183.029 114.760 1.00 103.19 ? 15  GLY S CA  1 
ATOM   4963 C C   . GLY D 4 15  ? 114.806 182.069 115.200 1.00 105.36 ? 15  GLY S C   1 
ATOM   4964 O O   . GLY D 4 15  ? 114.614 181.890 116.407 1.00 108.63 ? 15  GLY S O   1 
ATOM   4965 N N   . GLY D 4 16  ? 114.098 181.447 114.268 1.00 109.86 ? 16  GLY S N   1 
ATOM   4966 C CA  . GLY D 4 16  ? 113.018 180.534 114.583 1.00 111.37 ? 16  GLY S CA  1 
ATOM   4967 C C   . GLY D 4 16  ? 113.481 179.103 114.733 1.00 112.58 ? 16  GLY S C   1 
ATOM   4968 O O   . GLY D 4 16  ? 114.641 178.827 115.055 1.00 111.68 ? 16  GLY S O   1 
ATOM   4969 N N   . SER D 4 17  ? 112.555 178.175 114.501 1.00 107.39 ? 17  SER S N   1 
ATOM   4970 C CA  . SER D 4 17  ? 112.841 176.753 114.600 1.00 106.06 ? 17  SER S CA  1 
ATOM   4971 C C   . SER D 4 17  ? 112.152 176.018 113.461 1.00 107.96 ? 17  SER S C   1 
ATOM   4972 O O   . SER D 4 17  ? 111.113 176.451 112.958 1.00 109.78 ? 17  SER S O   1 
ATOM   4973 C CB  . SER D 4 17  ? 112.386 176.179 115.947 1.00 107.32 ? 17  SER S CB  1 
ATOM   4974 O OG  . SER D 4 17  ? 113.064 176.806 117.021 1.00 111.09 ? 17  SER S OG  1 
ATOM   4975 N N   . ARG D 4 18  ? 112.745 174.897 113.063 1.00 104.26 ? 18  ARG S N   1 
ATOM   4976 C CA  . ARG D 4 18  ? 112.205 174.082 111.983 1.00 101.22 ? 18  ARG S CA  1 
ATOM   4977 C C   . ARG D 4 18  ? 112.684 172.650 112.164 1.00 104.21 ? 18  ARG S C   1 
ATOM   4978 O O   . ARG D 4 18  ? 113.569 172.365 112.972 1.00 108.46 ? 18  ARG S O   1 
ATOM   4979 C CB  . ARG D 4 18  ? 112.612 174.627 110.612 1.00 100.95 ? 18  ARG S CB  1 
ATOM   4980 C CG  . ARG D 4 18  ? 111.451 175.174 109.805 1.00 102.91 ? 18  ARG S CG  1 
ATOM   4981 C CD  . ARG D 4 18  ? 110.496 174.065 109.406 1.00 102.99 ? 18  ARG S CD  1 
ATOM   4982 N NE  . ARG D 4 18  ? 109.804 174.363 108.159 1.00 107.30 ? 18  ARG S NE  1 
ATOM   4983 C CZ  . ARG D 4 18  ? 108.747 175.157 108.059 1.00 107.55 ? 18  ARG S CZ  1 
ATOM   4984 N NH1 . ARG D 4 18  ? 108.229 175.755 109.118 1.00 106.92 ? 18  ARG S NH1 1 
ATOM   4985 N NH2 . ARG D 4 18  ? 108.196 175.356 106.865 1.00 102.72 ? 18  ARG S NH2 1 
ATOM   4986 N N   . LYS D 4 19  ? 112.074 171.744 111.402 1.00 93.73  ? 19  LYS S N   1 
ATOM   4987 C CA  . LYS D 4 19  ? 112.427 170.331 111.447 1.00 92.69  ? 19  LYS S CA  1 
ATOM   4988 C C   . LYS D 4 19  ? 112.439 169.781 110.030 1.00 94.99  ? 19  LYS S C   1 
ATOM   4989 O O   . LYS D 4 19  ? 111.444 169.897 109.310 1.00 100.01 ? 19  LYS S O   1 
ATOM   4990 C CB  . LYS D 4 19  ? 111.448 169.542 112.320 1.00 92.03  ? 19  LYS S CB  1 
ATOM   4991 C CG  . LYS D 4 19  ? 112.118 168.561 113.265 1.00 93.46  ? 19  LYS S CG  1 
ATOM   4992 C CD  . LYS D 4 19  ? 111.096 167.729 114.018 1.00 93.97  ? 19  LYS S CD  1 
ATOM   4993 C CE  . LYS D 4 19  ? 110.155 167.015 113.065 1.00 93.80  ? 19  LYS S CE  1 
ATOM   4994 N NZ  . LYS D 4 19  ? 109.121 166.232 113.794 1.00 91.92  ? 19  LYS S NZ  1 
ATOM   4995 N N   . LEU D 4 20  ? 113.560 169.187 109.637 1.00 91.98  ? 20  LEU S N   1 
ATOM   4996 C CA  . LEU D 4 20  ? 113.693 168.530 108.344 1.00 92.94  ? 20  LEU S CA  1 
ATOM   4997 C C   . LEU D 4 20  ? 113.585 167.025 108.544 1.00 97.78  ? 20  LEU S C   1 
ATOM   4998 O O   . LEU D 4 20  ? 114.253 166.465 109.420 1.00 99.88  ? 20  LEU S O   1 
ATOM   4999 C CB  . LEU D 4 20  ? 115.027 168.881 107.686 1.00 89.93  ? 20  LEU S CB  1 
ATOM   5000 C CG  . LEU D 4 20  ? 115.453 170.347 107.743 1.00 93.37  ? 20  LEU S CG  1 
ATOM   5001 C CD1 . LEU D 4 20  ? 116.803 170.534 107.078 1.00 95.17  ? 20  LEU S CD1 1 
ATOM   5002 C CD2 . LEU D 4 20  ? 114.410 171.235 107.097 1.00 96.28  ? 20  LEU S CD2 1 
ATOM   5003 N N   . SER D 4 21  ? 112.747 166.373 107.740 1.00 96.18  ? 21  SER S N   1 
ATOM   5004 C CA  . SER D 4 21  ? 112.483 164.947 107.884 1.00 94.62  ? 21  SER S CA  1 
ATOM   5005 C C   . SER D 4 21  ? 112.856 164.229 106.596 1.00 97.77  ? 21  SER S C   1 
ATOM   5006 O O   . SER D 4 21  ? 112.257 164.481 105.547 1.00 101.51 ? 21  SER S O   1 
ATOM   5007 C CB  . SER D 4 21  ? 111.015 164.700 108.231 1.00 98.81  ? 21  SER S CB  1 
ATOM   5008 O OG  . SER D 4 21  ? 110.168 165.122 107.176 1.00 103.16 ? 21  SER S OG  1 
ATOM   5009 N N   . CYS D 4 22  ? 113.833 163.333 106.680 1.00 98.79  ? 22  CYS S N   1 
ATOM   5010 C CA  . CYS D 4 22  ? 114.220 162.470 105.574 1.00 99.62  ? 22  CYS S CA  1 
ATOM   5011 C C   . CYS D 4 22  ? 113.525 161.127 105.758 1.00 103.09 ? 22  CYS S C   1 
ATOM   5012 O O   . CYS D 4 22  ? 113.774 160.428 106.746 1.00 103.50 ? 22  CYS S O   1 
ATOM   5013 C CB  . CYS D 4 22  ? 115.738 162.297 105.524 1.00 103.22 ? 22  CYS S CB  1 
ATOM   5014 S SG  . CYS D 4 22  ? 116.359 161.357 104.112 1.00 122.34 ? 22  CYS S SG  1 
ATOM   5015 N N   . SER D 4 23  ? 112.654 160.777 104.816 1.00 95.57  ? 23  SER S N   1 
ATOM   5016 C CA  . SER D 4 23  ? 111.839 159.565 104.900 1.00 92.71  ? 23  SER S CA  1 
ATOM   5017 C C   . SER D 4 23  ? 112.466 158.507 104.000 1.00 92.76  ? 23  SER S C   1 
ATOM   5018 O O   . SER D 4 23  ? 112.142 158.397 102.817 1.00 92.08  ? 23  SER S O   1 
ATOM   5019 C CB  . SER D 4 23  ? 110.397 159.857 104.508 1.00 91.00  ? 23  SER S CB  1 
ATOM   5020 O OG  . SER D 4 23  ? 109.622 158.672 104.503 1.00 95.14  ? 23  SER S OG  1 
ATOM   5021 N N   . ALA D 4 24  ? 113.373 157.721 104.571 1.00 88.98  ? 24  ALA S N   1 
ATOM   5022 C CA  . ALA D 4 24  ? 114.058 156.688 103.811 1.00 83.05  ? 24  ALA S CA  1 
ATOM   5023 C C   . ALA D 4 24  ? 113.121 155.531 103.490 1.00 82.19  ? 24  ALA S C   1 
ATOM   5024 O O   . ALA D 4 24  ? 112.198 155.219 104.247 1.00 89.22  ? 24  ALA S O   1 
ATOM   5025 C CB  . ALA D 4 24  ? 115.265 156.168 104.585 1.00 85.73  ? 24  ALA S CB  1 
ATOM   5026 N N   . SER D 4 25  ? 113.369 154.891 102.351 1.00 81.76  ? 25  SER S N   1 
ATOM   5027 C CA  . SER D 4 25  ? 112.634 153.690 101.984 1.00 83.80  ? 25  SER S CA  1 
ATOM   5028 C C   . SER D 4 25  ? 113.466 152.893 100.993 1.00 82.66  ? 25  SER S C   1 
ATOM   5029 O O   . SER D 4 25  ? 114.307 153.447 100.281 1.00 92.02  ? 25  SER S O   1 
ATOM   5030 C CB  . SER D 4 25  ? 111.264 154.024 101.385 1.00 80.46  ? 25  SER S CB  1 
ATOM   5031 O OG  . SER D 4 25  ? 111.399 154.770 100.189 1.00 84.00  ? 25  SER S OG  1 
ATOM   5032 N N   . GLY D 4 26  ? 113.217 151.588 100.955 1.00 68.83  ? 26  GLY S N   1 
ATOM   5033 C CA  . GLY D 4 26  ? 113.883 150.721 100.007 1.00 73.28  ? 26  GLY S CA  1 
ATOM   5034 C C   . GLY D 4 26  ? 115.212 150.156 100.449 1.00 72.94  ? 26  GLY S C   1 
ATOM   5035 O O   . GLY D 4 26  ? 115.884 149.509 99.639  1.00 80.46  ? 26  GLY S O   1 
ATOM   5036 N N   . PHE D 4 27  ? 115.618 150.373 101.697 1.00 64.58  ? 27  PHE S N   1 
ATOM   5037 C CA  . PHE D 4 27  ? 116.861 149.799 102.195 1.00 72.74  ? 27  PHE S CA  1 
ATOM   5038 C C   . PHE D 4 27  ? 116.810 149.760 103.715 1.00 76.35  ? 27  PHE S C   1 
ATOM   5039 O O   . PHE D 4 27  ? 115.879 150.273 104.340 1.00 76.90  ? 27  PHE S O   1 
ATOM   5040 C CB  . PHE D 4 27  ? 118.084 150.578 101.695 1.00 74.60  ? 27  PHE S CB  1 
ATOM   5041 C CG  . PHE D 4 27  ? 118.293 151.896 102.379 1.00 74.66  ? 27  PHE S CG  1 
ATOM   5042 C CD1 . PHE D 4 27  ? 117.385 152.926 102.224 1.00 76.62  ? 27  PHE S CD1 1 
ATOM   5043 C CD2 . PHE D 4 27  ? 119.402 152.105 103.175 1.00 74.51  ? 27  PHE S CD2 1 
ATOM   5044 C CE1 . PHE D 4 27  ? 117.580 154.135 102.851 1.00 78.30  ? 27  PHE S CE1 1 
ATOM   5045 C CE2 . PHE D 4 27  ? 119.599 153.313 103.805 1.00 75.79  ? 27  PHE S CE2 1 
ATOM   5046 C CZ  . PHE D 4 27  ? 118.687 154.328 103.643 1.00 77.51  ? 27  PHE S CZ  1 
ATOM   5047 N N   . ALA D 4 28  ? 117.826 149.133 104.303 1.00 80.01  ? 28  ALA S N   1 
ATOM   5048 C CA  . ALA D 4 28  ? 117.890 148.942 105.749 1.00 79.22  ? 28  ALA S CA  1 
ATOM   5049 C C   . ALA D 4 28  ? 118.359 150.233 106.409 1.00 87.86  ? 28  ALA S C   1 
ATOM   5050 O O   . ALA D 4 28  ? 119.537 150.591 106.322 1.00 90.54  ? 28  ALA S O   1 
ATOM   5051 C CB  . ALA D 4 28  ? 118.821 147.784 106.091 1.00 80.16  ? 28  ALA S CB  1 
ATOM   5052 N N   . PHE D 4 29  ? 117.435 150.932 107.071 1.00 86.40  ? 29  PHE S N   1 
ATOM   5053 C CA  . PHE D 4 29  ? 117.778 152.186 107.733 1.00 79.44  ? 29  PHE S CA  1 
ATOM   5054 C C   . PHE D 4 29  ? 118.768 151.966 108.870 1.00 77.11  ? 29  PHE S C   1 
ATOM   5055 O O   . PHE D 4 29  ? 119.743 152.713 109.002 1.00 84.03  ? 29  PHE S O   1 
ATOM   5056 C CB  . PHE D 4 29  ? 116.504 152.857 108.250 1.00 85.42  ? 29  PHE S CB  1 
ATOM   5057 C CG  . PHE D 4 29  ? 116.632 154.340 108.475 1.00 85.00  ? 29  PHE S CG  1 
ATOM   5058 C CD1 . PHE D 4 29  ? 117.575 154.855 109.345 1.00 83.58  ? 29  PHE S CD1 1 
ATOM   5059 C CD2 . PHE D 4 29  ? 115.794 155.219 107.822 1.00 85.20  ? 29  PHE S CD2 1 
ATOM   5060 C CE1 . PHE D 4 29  ? 117.682 156.212 109.549 1.00 80.72  ? 29  PHE S CE1 1 
ATOM   5061 C CE2 . PHE D 4 29  ? 115.898 156.578 108.023 1.00 86.93  ? 29  PHE S CE2 1 
ATOM   5062 C CZ  . PHE D 4 29  ? 116.844 157.074 108.887 1.00 83.83  ? 29  PHE S CZ  1 
ATOM   5063 N N   . SER D 4 30  ? 118.539 150.942 109.694 1.00 72.70  ? 30  SER S N   1 
ATOM   5064 C CA  . SER D 4 30  ? 119.300 150.800 110.931 1.00 76.32  ? 30  SER S CA  1 
ATOM   5065 C C   . SER D 4 30  ? 120.784 150.589 110.661 1.00 79.76  ? 30  SER S C   1 
ATOM   5066 O O   . SER D 4 30  ? 121.634 151.147 111.364 1.00 85.03  ? 30  SER S O   1 
ATOM   5067 C CB  . SER D 4 30  ? 118.739 149.645 111.758 1.00 80.43  ? 30  SER S CB  1 
ATOM   5068 O OG  . SER D 4 30  ? 117.355 149.824 112.003 1.00 85.11  ? 30  SER S OG  1 
ATOM   5069 N N   . SER D 4 31  ? 121.117 149.784 109.652 1.00 76.42  ? 31  SER S N   1 
ATOM   5070 C CA  . SER D 4 31  ? 122.517 149.459 109.404 1.00 79.59  ? 31  SER S CA  1 
ATOM   5071 C C   . SER D 4 31  ? 123.304 150.664 108.907 1.00 78.13  ? 31  SER S C   1 
ATOM   5072 O O   . SER D 4 31  ? 124.526 150.716 109.081 1.00 82.91  ? 31  SER S O   1 
ATOM   5073 C CB  . SER D 4 31  ? 122.618 148.313 108.400 1.00 81.23  ? 31  SER S CB  1 
ATOM   5074 O OG  . SER D 4 31  ? 122.729 147.066 109.063 1.00 84.50  ? 31  SER S OG  1 
ATOM   5075 N N   . PHE D 4 32  ? 122.633 151.634 108.299 1.00 70.37  ? 32  PHE S N   1 
ATOM   5076 C CA  . PHE D 4 32  ? 123.305 152.767 107.683 1.00 66.90  ? 32  PHE S CA  1 
ATOM   5077 C C   . PHE D 4 32  ? 123.447 153.925 108.659 1.00 76.55  ? 32  PHE S C   1 
ATOM   5078 O O   . PHE D 4 32  ? 122.583 154.163 109.506 1.00 87.02  ? 32  PHE S O   1 
ATOM   5079 C CB  . PHE D 4 32  ? 122.536 153.240 106.451 1.00 67.54  ? 32  PHE S CB  1 
ATOM   5080 C CG  . PHE D 4 32  ? 122.851 152.469 105.208 1.00 69.89  ? 32  PHE S CG  1 
ATOM   5081 C CD1 . PHE D 4 32  ? 122.231 151.264 104.955 1.00 72.31  ? 32  PHE S CD1 1 
ATOM   5082 C CD2 . PHE D 4 32  ? 123.767 152.949 104.293 1.00 72.70  ? 32  PHE S CD2 1 
ATOM   5083 C CE1 . PHE D 4 32  ? 122.516 150.555 103.816 1.00 71.87  ? 32  PHE S CE1 1 
ATOM   5084 C CE2 . PHE D 4 32  ? 124.056 152.241 103.151 1.00 72.82  ? 32  PHE S CE2 1 
ATOM   5085 C CZ  . PHE D 4 32  ? 123.430 151.042 102.913 1.00 70.29  ? 32  PHE S CZ  1 
ATOM   5086 N N   . GLY D 4 33  ? 124.556 154.648 108.530 1.00 71.71  ? 33  GLY S N   1 
ATOM   5087 C CA  . GLY D 4 33  ? 124.708 155.926 109.196 1.00 65.23  ? 33  GLY S CA  1 
ATOM   5088 C C   . GLY D 4 33  ? 124.110 157.023 108.331 1.00 64.36  ? 33  GLY S C   1 
ATOM   5089 O O   . GLY D 4 33  ? 124.077 156.917 107.108 1.00 79.31  ? 33  GLY S O   1 
ATOM   5090 N N   . MET D 4 34  ? 123.632 158.076 108.980 1.00 58.95  ? 34  MET S N   1 
ATOM   5091 C CA  . MET D 4 34  ? 122.961 159.165 108.288 1.00 63.98  ? 34  MET S CA  1 
ATOM   5092 C C   . MET D 4 34  ? 123.783 160.440 108.389 1.00 78.50  ? 34  MET S C   1 
ATOM   5093 O O   . MET D 4 34  ? 124.353 160.744 109.442 1.00 87.56  ? 34  MET S O   1 
ATOM   5094 C CB  . MET D 4 34  ? 121.563 159.394 108.857 1.00 70.08  ? 34  MET S CB  1 
ATOM   5095 C CG  . MET D 4 34  ? 120.538 158.399 108.356 1.00 75.48  ? 34  MET S CG  1 
ATOM   5096 S SD  . MET D 4 34  ? 120.732 158.064 106.599 1.00 93.26  ? 34  MET S SD  1 
ATOM   5097 C CE  . MET D 4 34  ? 119.024 158.054 106.071 1.00 79.22  ? 34  MET S CE  1 
ATOM   5098 N N   . HIS D 4 35  ? 123.844 161.176 107.284 1.00 72.25  ? 35  HIS S N   1 
ATOM   5099 C CA  . HIS D 4 35  ? 124.554 162.441 107.203 1.00 61.35  ? 35  HIS S CA  1 
ATOM   5100 C C   . HIS D 4 35  ? 123.601 163.512 106.705 1.00 73.16  ? 35  HIS S C   1 
ATOM   5101 O O   . HIS D 4 35  ? 122.789 163.262 105.813 1.00 82.23  ? 35  HIS S O   1 
ATOM   5102 C CB  . HIS D 4 35  ? 125.742 162.357 106.250 1.00 56.16  ? 35  HIS S CB  1 
ATOM   5103 C CG  . HIS D 4 35  ? 126.928 161.650 106.817 1.00 57.78  ? 35  HIS S CG  1 
ATOM   5104 N ND1 . HIS D 4 35  ? 127.964 162.314 107.433 1.00 70.81  ? 35  HIS S ND1 1 
ATOM   5105 C CD2 . HIS D 4 35  ? 127.252 160.337 106.846 1.00 66.35  ? 35  HIS S CD2 1 
ATOM   5106 C CE1 . HIS D 4 35  ? 128.874 161.440 107.823 1.00 74.65  ? 35  HIS S CE1 1 
ATOM   5107 N NE2 . HIS D 4 35  ? 128.466 160.233 107.479 1.00 77.18  ? 35  HIS S NE2 1 
ATOM   5108 N N   . TRP D 4 36  ? 123.703 164.700 107.279 1.00 79.87  ? 36  TRP S N   1 
ATOM   5109 C CA  . TRP D 4 36  ? 123.033 165.884 106.763 1.00 69.33  ? 36  TRP S CA  1 
ATOM   5110 C C   . TRP D 4 36  ? 124.101 166.778 106.160 1.00 74.76  ? 36  TRP S C   1 
ATOM   5111 O O   . TRP D 4 36  ? 125.018 167.211 106.870 1.00 87.25  ? 36  TRP S O   1 
ATOM   5112 C CB  . TRP D 4 36  ? 122.271 166.618 107.863 1.00 71.12  ? 36  TRP S CB  1 
ATOM   5113 C CG  . TRP D 4 36  ? 120.889 166.125 108.055 1.00 72.83  ? 36  TRP S CG  1 
ATOM   5114 C CD1 . TRP D 4 36  ? 120.441 165.326 109.058 1.00 79.48  ? 36  TRP S CD1 1 
ATOM   5115 C CD2 . TRP D 4 36  ? 119.760 166.397 107.222 1.00 72.69  ? 36  TRP S CD2 1 
ATOM   5116 N NE1 . TRP D 4 36  ? 119.101 165.081 108.905 1.00 79.52  ? 36  TRP S NE1 1 
ATOM   5117 C CE2 . TRP D 4 36  ? 118.659 165.727 107.782 1.00 73.51  ? 36  TRP S CE2 1 
ATOM   5118 C CE3 . TRP D 4 36  ? 119.574 167.141 106.056 1.00 83.29  ? 36  TRP S CE3 1 
ATOM   5119 C CZ2 . TRP D 4 36  ? 117.391 165.779 107.219 1.00 74.95  ? 36  TRP S CZ2 1 
ATOM   5120 C CZ3 . TRP D 4 36  ? 118.314 167.192 105.499 1.00 86.87  ? 36  TRP S CZ3 1 
ATOM   5121 C CH2 . TRP D 4 36  ? 117.239 166.515 106.080 1.00 81.25  ? 36  TRP S CH2 1 
ATOM   5122 N N   . VAL D 4 37  ? 123.984 167.040 104.859 1.00 71.92  ? 37  VAL S N   1 
ATOM   5123 C CA  . VAL D 4 37  ? 124.956 167.833 104.116 1.00 70.57  ? 37  VAL S CA  1 
ATOM   5124 C C   . VAL D 4 37  ? 124.219 168.975 103.435 1.00 76.49  ? 37  VAL S C   1 
ATOM   5125 O O   . VAL D 4 37  ? 123.200 168.755 102.772 1.00 86.21  ? 37  VAL S O   1 
ATOM   5126 C CB  . VAL D 4 37  ? 125.715 166.983 103.081 1.00 70.26  ? 37  VAL S CB  1 
ATOM   5127 C CG1 . VAL D 4 37  ? 126.471 167.873 102.117 1.00 74.36  ? 37  VAL S CG1 1 
ATOM   5128 C CG2 . VAL D 4 37  ? 126.661 166.029 103.778 1.00 76.14  ? 37  VAL S CG2 1 
ATOM   5129 N N   . ARG D 4 38  ? 124.730 170.189 103.593 1.00 80.91  ? 38  ARG S N   1 
ATOM   5130 C CA  . ARG D 4 38  ? 124.084 171.368 103.042 1.00 80.54  ? 38  ARG S CA  1 
ATOM   5131 C C   . ARG D 4 38  ? 124.921 171.963 101.920 1.00 76.95  ? 38  ARG S C   1 
ATOM   5132 O O   . ARG D 4 38  ? 126.133 171.751 101.828 1.00 75.39  ? 38  ARG S O   1 
ATOM   5133 C CB  . ARG D 4 38  ? 123.838 172.422 104.127 1.00 88.20  ? 38  ARG S CB  1 
ATOM   5134 C CG  . ARG D 4 38  ? 125.029 173.315 104.408 1.00 86.51  ? 38  ARG S CG  1 
ATOM   5135 C CD  . ARG D 4 38  ? 124.602 174.736 104.722 1.00 84.22  ? 38  ARG S CD  1 
ATOM   5136 N NE  . ARG D 4 38  ? 123.944 174.833 106.018 1.00 80.39  ? 38  ARG S NE  1 
ATOM   5137 C CZ  . ARG D 4 38  ? 124.415 175.528 107.043 1.00 77.67  ? 38  ARG S CZ  1 
ATOM   5138 N NH1 . ARG D 4 38  ? 125.564 176.177 106.967 1.00 76.33  ? 38  ARG S NH1 1 
ATOM   5139 N NH2 . ARG D 4 38  ? 123.717 175.570 108.173 1.00 83.22  ? 38  ARG S NH2 1 
ATOM   5140 N N   . GLN D 4 39  ? 124.240 172.708 101.056 1.00 82.76  ? 39  GLN S N   1 
ATOM   5141 C CA  . GLN D 4 39  ? 124.859 173.383 99.925  1.00 89.77  ? 39  GLN S CA  1 
ATOM   5142 C C   . GLN D 4 39  ? 124.294 174.790 99.854  1.00 93.67  ? 39  GLN S C   1 
ATOM   5143 O O   . GLN D 4 39  ? 123.075 174.962 99.784  1.00 88.93  ? 39  GLN S O   1 
ATOM   5144 C CB  . GLN D 4 39  ? 124.589 172.628 98.620  1.00 90.54  ? 39  GLN S CB  1 
ATOM   5145 C CG  . GLN D 4 39  ? 125.663 172.786 97.564  1.00 88.11  ? 39  GLN S CG  1 
ATOM   5146 C CD  . GLN D 4 39  ? 125.109 172.673 96.160  1.00 89.94  ? 39  GLN S CD  1 
ATOM   5147 O OE1 . GLN D 4 39  ? 123.896 172.629 95.961  1.00 87.65  ? 39  GLN S OE1 1 
ATOM   5148 N NE2 . GLN D 4 39  ? 125.997 172.626 95.175  1.00 94.17  ? 39  GLN S NE2 1 
ATOM   5149 N N   . ALA D 4 40  ? 125.168 175.790 99.882  1.00 103.74 ? 40  ALA S N   1 
ATOM   5150 C CA  . ALA D 4 40  ? 124.702 177.157 99.739  1.00 98.19  ? 40  ALA S CA  1 
ATOM   5151 C C   . ALA D 4 40  ? 124.036 177.321 98.374  1.00 101.09 ? 40  ALA S C   1 
ATOM   5152 O O   . ALA D 4 40  ? 124.411 176.644 97.412  1.00 107.41 ? 40  ALA S O   1 
ATOM   5153 C CB  . ALA D 4 40  ? 125.858 178.140 99.895  1.00 98.98  ? 40  ALA S CB  1 
ATOM   5154 N N   . PRO D 4 41  ? 123.035 178.199 98.267  1.00 97.33  ? 41  PRO S N   1 
ATOM   5155 C CA  . PRO D 4 41  ? 122.222 178.235 97.037  1.00 99.55  ? 41  PRO S CA  1 
ATOM   5156 C C   . PRO D 4 41  ? 123.025 178.385 95.755  1.00 101.70 ? 41  PRO S C   1 
ATOM   5157 O O   . PRO D 4 41  ? 122.693 177.750 94.746  1.00 101.13 ? 41  PRO S O   1 
ATOM   5158 C CB  . PRO D 4 41  ? 121.301 179.435 97.280  1.00 94.83  ? 41  PRO S CB  1 
ATOM   5159 C CG  . PRO D 4 41  ? 121.156 179.504 98.751  1.00 97.66  ? 41  PRO S CG  1 
ATOM   5160 C CD  . PRO D 4 41  ? 122.452 179.020 99.342  1.00 96.97  ? 41  PRO S CD  1 
ATOM   5161 N N   . GLU D 4 42  ? 124.080 179.200 95.762  1.00 107.42 ? 42  GLU S N   1 
ATOM   5162 C CA  . GLU D 4 42  ? 124.927 179.385 94.590  1.00 107.25 ? 42  GLU S CA  1 
ATOM   5163 C C   . GLU D 4 42  ? 126.350 178.879 94.808  1.00 106.31 ? 42  GLU S C   1 
ATOM   5164 O O   . GLU D 4 42  ? 127.219 179.111 93.962  1.00 105.11 ? 42  GLU S O   1 
ATOM   5165 C CB  . GLU D 4 42  ? 124.964 180.859 94.169  1.00 110.15 ? 42  GLU S CB  1 
ATOM   5166 C CG  . GLU D 4 42  ? 123.682 181.708 94.324  1.00 112.28 ? 42  GLU S CG  1 
ATOM   5167 C CD  . GLU D 4 42  ? 122.370 180.970 94.074  1.00 116.41 ? 42  GLU S CD  1 
ATOM   5168 O OE1 . GLU D 4 42  ? 122.331 180.047 93.233  1.00 116.02 ? 42  GLU S OE1 1 
ATOM   5169 O OE2 . GLU D 4 42  ? 121.364 181.329 94.721  1.00 116.22 ? 42  GLU S OE2 1 
ATOM   5170 N N   . LYS D 4 43  ? 126.610 178.193 95.915  1.00 98.32  ? 43  LYS S N   1 
ATOM   5171 C CA  . LYS D 4 43  ? 127.964 177.791 96.273  1.00 98.33  ? 43  LYS S CA  1 
ATOM   5172 C C   . LYS D 4 43  ? 128.027 176.278 96.484  1.00 98.54  ? 43  LYS S C   1 
ATOM   5173 O O   . LYS D 4 43  ? 127.076 175.546 96.200  1.00 95.64  ? 43  LYS S O   1 
ATOM   5174 C CB  . LYS D 4 43  ? 128.437 178.551 97.514  1.00 96.13  ? 43  LYS S CB  1 
ATOM   5175 C CG  . LYS D 4 43  ? 127.960 179.992 97.579  1.00 97.78  ? 43  LYS S CG  1 
ATOM   5176 C CD  . LYS D 4 43  ? 128.998 180.889 98.225  1.00 99.65  ? 43  LYS S CD  1 
ATOM   5177 C CE  . LYS D 4 43  ? 129.106 180.612 99.715  1.00 100.27 ? 43  LYS S CE  1 
ATOM   5178 N NZ  . LYS D 4 43  ? 127.869 181.005 100.445 1.00 99.37  ? 43  LYS S NZ  1 
ATOM   5179 N N   . GLY D 4 44  ? 129.169 175.815 96.991  1.00 96.11  ? 44  GLY S N   1 
ATOM   5180 C CA  . GLY D 4 44  ? 129.430 174.399 97.125  1.00 94.45  ? 44  GLY S CA  1 
ATOM   5181 C C   . GLY D 4 44  ? 128.835 173.788 98.380  1.00 94.72  ? 44  GLY S C   1 
ATOM   5182 O O   . GLY D 4 44  ? 128.130 174.428 99.160  1.00 99.93  ? 44  GLY S O   1 
ATOM   5183 N N   . LEU D 4 45  ? 129.134 172.506 98.564  1.00 83.58  ? 45  LEU S N   1 
ATOM   5184 C CA  . LEU D 4 45  ? 128.607 171.732 99.675  1.00 85.13  ? 45  LEU S CA  1 
ATOM   5185 C C   . LEU D 4 45  ? 129.372 172.027 100.961 1.00 89.57  ? 45  LEU S C   1 
ATOM   5186 O O   . LEU D 4 45  ? 130.491 172.546 100.947 1.00 90.22  ? 45  LEU S O   1 
ATOM   5187 C CB  . LEU D 4 45  ? 128.685 170.236 99.371  1.00 86.95  ? 45  LEU S CB  1 
ATOM   5188 C CG  . LEU D 4 45  ? 127.813 169.673 98.251  1.00 86.12  ? 45  LEU S CG  1 
ATOM   5189 C CD1 . LEU D 4 45  ? 128.410 168.380 97.739  1.00 84.98  ? 45  LEU S CD1 1 
ATOM   5190 C CD2 . LEU D 4 45  ? 126.399 169.443 98.741  1.00 91.50  ? 45  LEU S CD2 1 
ATOM   5191 N N   . GLU D 4 46  ? 128.746 171.687 102.087 1.00 87.68  ? 46  GLU S N   1 
ATOM   5192 C CA  . GLU D 4 46  ? 129.412 171.722 103.382 1.00 83.92  ? 46  GLU S CA  1 
ATOM   5193 C C   . GLU D 4 46  ? 128.719 170.725 104.297 1.00 82.97  ? 46  GLU S C   1 
ATOM   5194 O O   . GLU D 4 46  ? 127.486 170.660 104.333 1.00 82.41  ? 46  GLU S O   1 
ATOM   5195 C CB  . GLU D 4 46  ? 129.407 173.134 103.987 1.00 86.29  ? 46  GLU S CB  1 
ATOM   5196 C CG  . GLU D 4 46  ? 130.237 174.171 103.247 1.00 91.65  ? 46  GLU S CG  1 
ATOM   5197 C CD  . GLU D 4 46  ? 130.131 175.555 103.854 1.00 96.44  ? 46  GLU S CD  1 
ATOM   5198 O OE1 . GLU D 4 46  ? 129.267 175.756 104.734 1.00 90.92  ? 46  GLU S OE1 1 
ATOM   5199 O OE2 . GLU D 4 46  ? 130.907 176.445 103.447 1.00 98.82  ? 46  GLU S OE2 1 
ATOM   5200 N N   . TRP D 4 47  ? 129.513 169.913 104.987 1.00 79.00  ? 47  TRP S N   1 
ATOM   5201 C CA  . TRP D 4 47  ? 128.961 168.915 105.891 1.00 77.80  ? 47  TRP S CA  1 
ATOM   5202 C C   . TRP D 4 47  ? 128.332 169.593 107.101 1.00 76.41  ? 47  TRP S C   1 
ATOM   5203 O O   . TRP D 4 47  ? 128.858 170.581 107.620 1.00 84.82  ? 47  TRP S O   1 
ATOM   5204 C CB  . TRP D 4 47  ? 130.056 167.942 106.325 1.00 76.49  ? 47  TRP S CB  1 
ATOM   5205 C CG  . TRP D 4 47  ? 129.654 167.018 107.419 1.00 72.11  ? 47  TRP S CG  1 
ATOM   5206 C CD1 . TRP D 4 47  ? 128.758 165.999 107.338 1.00 78.73  ? 47  TRP S CD1 1 
ATOM   5207 C CD2 . TRP D 4 47  ? 130.148 167.014 108.761 1.00 76.05  ? 47  TRP S CD2 1 
ATOM   5208 N NE1 . TRP D 4 47  ? 128.654 165.363 108.549 1.00 80.76  ? 47  TRP S NE1 1 
ATOM   5209 C CE2 . TRP D 4 47  ? 129.499 165.967 109.440 1.00 76.53  ? 47  TRP S CE2 1 
ATOM   5210 C CE3 . TRP D 4 47  ? 131.074 167.796 109.456 1.00 81.10  ? 47  TRP S CE3 1 
ATOM   5211 C CZ2 . TRP D 4 47  ? 129.746 165.682 110.779 1.00 79.11  ? 47  TRP S CZ2 1 
ATOM   5212 C CZ3 . TRP D 4 47  ? 131.317 167.512 110.785 1.00 83.67  ? 47  TRP S CZ3 1 
ATOM   5213 C CH2 . TRP D 4 47  ? 130.656 166.464 111.433 1.00 85.76  ? 47  TRP S CH2 1 
ATOM   5214 N N   . VAL D 4 48  ? 127.198 169.064 107.551 1.00 63.86  ? 48  VAL S N   1 
ATOM   5215 C CA  . VAL D 4 48  ? 126.437 169.653 108.650 1.00 69.37  ? 48  VAL S CA  1 
ATOM   5216 C C   . VAL D 4 48  ? 126.402 168.731 109.864 1.00 71.86  ? 48  VAL S C   1 
ATOM   5217 O O   . VAL D 4 48  ? 126.840 169.108 110.951 1.00 80.62  ? 48  VAL S O   1 
ATOM   5218 C CB  . VAL D 4 48  ? 125.012 170.041 108.200 1.00 76.34  ? 48  VAL S CB  1 
ATOM   5219 C CG1 . VAL D 4 48  ? 124.105 170.224 109.403 1.00 76.52  ? 48  VAL S CG1 1 
ATOM   5220 C CG2 . VAL D 4 48  ? 125.054 171.307 107.377 1.00 78.61  ? 48  VAL S CG2 1 
ATOM   5221 N N   . ALA D 4 49  ? 125.886 167.516 109.701 1.00 72.57  ? 49  ALA S N   1 
ATOM   5222 C CA  . ALA D 4 49  ? 125.647 166.671 110.864 1.00 72.16  ? 49  ALA S CA  1 
ATOM   5223 C C   . ALA D 4 49  ? 125.767 165.203 110.484 1.00 78.53  ? 49  ALA S C   1 
ATOM   5224 O O   . ALA D 4 49  ? 125.729 164.840 109.309 1.00 88.36  ? 49  ALA S O   1 
ATOM   5225 C CB  . ALA D 4 49  ? 124.274 166.954 111.479 1.00 76.56  ? 49  ALA S CB  1 
ATOM   5226 N N   . TYR D 4 50  ? 125.889 164.355 111.504 1.00 76.20  ? 50  TYR S N   1 
ATOM   5227 C CA  . TYR D 4 50  ? 126.032 162.924 111.281 1.00 68.78  ? 50  TYR S CA  1 
ATOM   5228 C C   . TYR D 4 50  ? 125.585 162.157 112.515 1.00 66.54  ? 50  TYR S C   1 
ATOM   5229 O O   . TYR D 4 50  ? 125.906 162.544 113.641 1.00 78.41  ? 50  TYR S O   1 
ATOM   5230 C CB  . TYR D 4 50  ? 127.480 162.565 110.949 1.00 69.92  ? 50  TYR S CB  1 
ATOM   5231 C CG  . TYR D 4 50  ? 127.864 161.141 111.278 1.00 70.46  ? 50  TYR S CG  1 
ATOM   5232 C CD1 . TYR D 4 50  ? 127.434 160.088 110.486 1.00 70.06  ? 50  TYR S CD1 1 
ATOM   5233 C CD2 . TYR D 4 50  ? 128.666 160.851 112.370 1.00 74.97  ? 50  TYR S CD2 1 
ATOM   5234 C CE1 . TYR D 4 50  ? 127.792 158.788 110.770 1.00 68.99  ? 50  TYR S CE1 1 
ATOM   5235 C CE2 . TYR D 4 50  ? 129.029 159.552 112.662 1.00 71.82  ? 50  TYR S CE2 1 
ATOM   5236 C CZ  . TYR D 4 50  ? 128.589 158.527 111.858 1.00 66.31  ? 50  TYR S CZ  1 
ATOM   5237 O OH  . TYR D 4 50  ? 128.947 157.233 112.142 1.00 73.10  ? 50  TYR S OH  1 
ATOM   5238 N N   . ILE D 4 51  ? 124.862 161.063 112.290 1.00 59.37  ? 51  ILE S N   1 
ATOM   5239 C CA  . ILE D 4 51  ? 124.532 160.098 113.330 1.00 62.14  ? 51  ILE S CA  1 
ATOM   5240 C C   . ILE D 4 51  ? 124.908 158.711 112.831 1.00 72.82  ? 51  ILE S C   1 
ATOM   5241 O O   . ILE D 4 51  ? 124.745 158.399 111.646 1.00 84.85  ? 51  ILE S O   1 
ATOM   5242 C CB  . ILE D 4 51  ? 123.045 160.146 113.727 1.00 57.30  ? 51  ILE S CB  1 
ATOM   5243 C CG1 . ILE D 4 51  ? 122.160 160.161 112.488 1.00 72.84  ? 51  ILE S CG1 1 
ATOM   5244 C CG2 . ILE D 4 51  ? 122.763 161.361 114.584 1.00 67.36  ? 51  ILE S CG2 1 
ATOM   5245 C CD1 . ILE D 4 51  ? 120.698 160.238 112.816 1.00 78.84  ? 51  ILE S CD1 1 
ATOM   5246 N N   . SER D 4 52  ? 125.429 157.885 113.731 1.00 69.15  ? 52  SER S N   1 
ATOM   5247 C CA  . SER D 4 52  ? 125.906 156.558 113.372 1.00 64.10  ? 52  SER S CA  1 
ATOM   5248 C C   . SER D 4 52  ? 124.759 155.555 113.448 1.00 74.63  ? 52  SER S C   1 
ATOM   5249 O O   . SER D 4 52  ? 123.600 155.910 113.677 1.00 84.78  ? 52  SER S O   1 
ATOM   5250 C CB  . SER D 4 52  ? 127.060 156.152 114.280 1.00 68.98  ? 52  SER S CB  1 
ATOM   5251 O OG  . SER D 4 52  ? 126.625 156.020 115.621 1.00 75.49  ? 52  SER S OG  1 
ATOM   5252 N N   . SER D 4 53  ? 125.078 154.279 113.253 1.00 79.06  ? 53  SER S N   1 
ATOM   5253 C CA  . SER D 4 53  ? 124.092 153.225 113.441 1.00 76.10  ? 53  SER S CA  1 
ATOM   5254 C C   . SER D 4 53  ? 123.791 153.067 114.925 1.00 82.69  ? 53  SER S C   1 
ATOM   5255 O O   . SER D 4 53  ? 124.706 152.955 115.746 1.00 84.93  ? 53  SER S O   1 
ATOM   5256 C CB  . SER D 4 53  ? 124.601 151.911 112.856 1.00 79.03  ? 53  SER S CB  1 
ATOM   5257 O OG  . SER D 4 53  ? 125.842 151.545 113.432 1.00 86.20  ? 53  SER S OG  1 
ATOM   5258 N N   . GLY D 4 54  ? 122.507 153.066 115.270 1.00 80.88  ? 54  GLY S N   1 
ATOM   5259 C CA  . GLY D 4 54  ? 122.105 152.979 116.658 1.00 78.10  ? 54  GLY S CA  1 
ATOM   5260 C C   . GLY D 4 54  ? 122.247 154.257 117.450 1.00 73.42  ? 54  GLY S C   1 
ATOM   5261 O O   . GLY D 4 54  ? 122.085 154.226 118.675 1.00 76.55  ? 54  GLY S O   1 
ATOM   5262 N N   . SER D 4 55  ? 122.556 155.376 116.792 1.00 69.53  ? 55  SER S N   1 
ATOM   5263 C CA  . SER D 4 55  ? 122.675 156.684 117.438 1.00 72.29  ? 55  SER S CA  1 
ATOM   5264 C C   . SER D 4 55  ? 123.758 156.694 118.513 1.00 72.25  ? 55  SER S C   1 
ATOM   5265 O O   . SER D 4 55  ? 123.691 157.471 119.467 1.00 79.90  ? 55  SER S O   1 
ATOM   5266 C CB  . SER D 4 55  ? 121.335 157.136 118.025 1.00 72.71  ? 55  SER S CB  1 
ATOM   5267 O OG  . SER D 4 55  ? 120.263 156.782 117.170 1.00 68.74  ? 55  SER S OG  1 
ATOM   5268 N N   . GLY D 4 56  ? 124.763 155.831 118.367 1.00 72.99  ? 56  GLY S N   1 
ATOM   5269 C CA  . GLY D 4 56  ? 125.826 155.780 119.357 1.00 72.89  ? 56  GLY S CA  1 
ATOM   5270 C C   . GLY D 4 56  ? 126.670 157.040 119.382 1.00 78.51  ? 56  GLY S C   1 
ATOM   5271 O O   . GLY D 4 56  ? 126.981 157.572 120.451 1.00 84.72  ? 56  GLY S O   1 
ATOM   5272 N N   . THR D 4 57  ? 127.054 157.535 118.208 1.00 72.13  ? 57  THR S N   1 
ATOM   5273 C CA  . THR D 4 57  ? 127.888 158.722 118.085 1.00 67.22  ? 57  THR S CA  1 
ATOM   5274 C C   . THR D 4 57  ? 127.202 159.737 117.186 1.00 70.11  ? 57  THR S C   1 
ATOM   5275 O O   . THR D 4 57  ? 126.714 159.387 116.107 1.00 81.00  ? 57  THR S O   1 
ATOM   5276 C CB  . THR D 4 57  ? 129.269 158.386 117.520 1.00 63.10  ? 57  THR S CB  1 
ATOM   5277 O OG1 . THR D 4 57  ? 129.144 158.009 116.145 1.00 69.51  ? 57  THR S OG1 1 
ATOM   5278 C CG2 . THR D 4 57  ? 129.910 157.255 118.303 1.00 70.25  ? 57  THR S CG2 1 
ATOM   5279 N N   . ILE D 4 58  ? 127.173 160.989 117.630 1.00 66.27  ? 58  ILE S N   1 
ATOM   5280 C CA  . ILE D 4 58  ? 126.583 162.087 116.876 1.00 59.09  ? 58  ILE S CA  1 
ATOM   5281 C C   . ILE D 4 58  ? 127.636 163.174 116.734 1.00 69.06  ? 58  ILE S C   1 
ATOM   5282 O O   . ILE D 4 58  ? 128.225 163.605 117.732 1.00 77.52  ? 58  ILE S O   1 
ATOM   5283 C CB  . ILE D 4 58  ? 125.325 162.642 117.559 1.00 59.49  ? 58  ILE S CB  1 
ATOM   5284 C CG1 . ILE D 4 58  ? 124.335 161.516 117.853 1.00 70.39  ? 58  ILE S CG1 1 
ATOM   5285 C CG2 . ILE D 4 58  ? 124.682 163.689 116.688 1.00 66.83  ? 58  ILE S CG2 1 
ATOM   5286 C CD1 . ILE D 4 58  ? 122.960 162.002 118.250 1.00 75.74  ? 58  ILE S CD1 1 
ATOM   5287 N N   . TYR D 4 59  ? 127.873 163.616 115.505 1.00 72.92  ? 59  TYR S N   1 
ATOM   5288 C CA  . TYR D 4 59  ? 128.850 164.655 115.220 1.00 60.28  ? 59  TYR S CA  1 
ATOM   5289 C C   . TYR D 4 59  ? 128.183 165.825 114.511 1.00 66.65  ? 59  TYR S C   1 
ATOM   5290 O O   . TYR D 4 59  ? 127.253 165.646 113.720 1.00 81.49  ? 59  TYR S O   1 
ATOM   5291 C CB  . TYR D 4 59  ? 129.993 164.119 114.358 1.00 60.72  ? 59  TYR S CB  1 
ATOM   5292 C CG  . TYR D 4 59  ? 130.930 163.183 115.081 1.00 65.98  ? 59  TYR S CG  1 
ATOM   5293 C CD1 . TYR D 4 59  ? 131.171 163.320 116.437 1.00 75.42  ? 59  TYR S CD1 1 
ATOM   5294 C CD2 . TYR D 4 59  ? 131.575 162.162 114.403 1.00 68.44  ? 59  TYR S CD2 1 
ATOM   5295 C CE1 . TYR D 4 59  ? 132.030 162.464 117.097 1.00 77.67  ? 59  TYR S CE1 1 
ATOM   5296 C CE2 . TYR D 4 59  ? 132.433 161.303 115.052 1.00 66.26  ? 59  TYR S CE2 1 
ATOM   5297 C CZ  . TYR D 4 59  ? 132.657 161.458 116.398 1.00 75.78  ? 59  TYR S CZ  1 
ATOM   5298 O OH  . TYR D 4 59  ? 133.513 160.601 117.047 1.00 83.24  ? 59  TYR S OH  1 
ATOM   5299 N N   . TYR D 4 60  ? 128.669 167.028 114.803 1.00 64.14  ? 60  TYR S N   1 
ATOM   5300 C CA  . TYR D 4 60  ? 128.174 168.246 114.182 1.00 69.52  ? 60  TYR S CA  1 
ATOM   5301 C C   . TYR D 4 60  ? 129.342 169.056 113.645 1.00 79.69  ? 60  TYR S C   1 
ATOM   5302 O O   . TYR D 4 60  ? 130.480 168.925 114.101 1.00 82.76  ? 60  TYR S O   1 
ATOM   5303 C CB  . TYR D 4 60  ? 127.381 169.115 115.164 1.00 68.88  ? 60  TYR S CB  1 
ATOM   5304 C CG  . TYR D 4 60  ? 126.126 168.480 115.697 1.00 65.60  ? 60  TYR S CG  1 
ATOM   5305 C CD1 . TYR D 4 60  ? 126.167 167.648 116.800 1.00 70.36  ? 60  TYR S CD1 1 
ATOM   5306 C CD2 . TYR D 4 60  ? 124.899 168.725 115.107 1.00 70.30  ? 60  TYR S CD2 1 
ATOM   5307 C CE1 . TYR D 4 60  ? 125.026 167.074 117.298 1.00 72.00  ? 60  TYR S CE1 1 
ATOM   5308 C CE2 . TYR D 4 60  ? 123.750 168.153 115.596 1.00 75.13  ? 60  TYR S CE2 1 
ATOM   5309 C CZ  . TYR D 4 60  ? 123.820 167.326 116.692 1.00 75.58  ? 60  TYR S CZ  1 
ATOM   5310 O OH  . TYR D 4 60  ? 122.681 166.744 117.192 1.00 79.17  ? 60  TYR S OH  1 
ATOM   5311 N N   . ALA D 4 61  ? 129.047 169.899 112.664 1.00 88.87  ? 61  ALA S N   1 
ATOM   5312 C CA  . ALA D 4 61  ? 130.015 170.890 112.236 1.00 85.61  ? 61  ALA S CA  1 
ATOM   5313 C C   . ALA D 4 61  ? 130.095 172.010 113.267 1.00 91.66  ? 61  ALA S C   1 
ATOM   5314 O O   . ALA D 4 61  ? 129.165 172.241 114.045 1.00 98.36  ? 61  ALA S O   1 
ATOM   5315 C CB  . ALA D 4 61  ? 129.646 171.455 110.865 1.00 87.53  ? 61  ALA S CB  1 
ATOM   5316 N N   . ASP D 4 62  ? 131.231 172.708 113.272 1.00 94.31  ? 62  ASP S N   1 
ATOM   5317 C CA  . ASP D 4 62  ? 131.420 173.783 114.239 1.00 95.88  ? 62  ASP S CA  1 
ATOM   5318 C C   . ASP D 4 62  ? 130.437 174.923 114.012 1.00 92.18  ? 62  ASP S C   1 
ATOM   5319 O O   . ASP D 4 62  ? 130.010 175.574 114.972 1.00 93.46  ? 62  ASP S O   1 
ATOM   5320 C CB  . ASP D 4 62  ? 132.857 174.297 114.175 1.00 98.97  ? 62  ASP S CB  1 
ATOM   5321 C CG  . ASP D 4 62  ? 133.855 173.290 114.704 1.00 101.35 ? 62  ASP S CG  1 
ATOM   5322 O OD1 . ASP D 4 62  ? 133.434 172.353 115.413 1.00 99.56  ? 62  ASP S OD1 1 
ATOM   5323 O OD2 . ASP D 4 62  ? 135.060 173.436 114.411 1.00 101.66 ? 62  ASP S OD2 1 
ATOM   5324 N N   . THR D 4 63  ? 130.066 175.179 112.757 1.00 77.09  ? 63  THR S N   1 
ATOM   5325 C CA  . THR D 4 63  ? 129.159 176.283 112.463 1.00 79.12  ? 63  THR S CA  1 
ATOM   5326 C C   . THR D 4 63  ? 127.772 176.039 113.045 1.00 76.33  ? 63  THR S C   1 
ATOM   5327 O O   . THR D 4 63  ? 127.120 176.975 113.521 1.00 80.24  ? 63  THR S O   1 
ATOM   5328 C CB  . THR D 4 63  ? 129.076 176.501 110.953 1.00 82.07  ? 63  THR S CB  1 
ATOM   5329 O OG1 . THR D 4 63  ? 130.390 176.725 110.430 1.00 85.08  ? 63  THR S OG1 1 
ATOM   5330 C CG2 . THR D 4 63  ? 128.205 177.704 110.634 1.00 84.72  ? 63  THR S CG2 1 
ATOM   5331 N N   . VAL D 4 64  ? 127.304 174.794 113.022 1.00 75.05  ? 64  VAL S N   1 
ATOM   5332 C CA  . VAL D 4 64  ? 125.948 174.464 113.436 1.00 81.08  ? 64  VAL S CA  1 
ATOM   5333 C C   . VAL D 4 64  ? 125.920 173.708 114.757 1.00 86.72  ? 64  VAL S C   1 
ATOM   5334 O O   . VAL D 4 64  ? 124.889 173.127 115.112 1.00 94.91  ? 64  VAL S O   1 
ATOM   5335 C CB  . VAL D 4 64  ? 125.210 173.680 112.340 1.00 88.55  ? 64  VAL S CB  1 
ATOM   5336 C CG1 . VAL D 4 64  ? 125.236 174.453 111.034 1.00 88.78  ? 64  VAL S CG1 1 
ATOM   5337 C CG2 . VAL D 4 64  ? 125.840 172.307 112.158 1.00 88.11  ? 64  VAL S CG2 1 
ATOM   5338 N N   . LYS D 4 65  ? 127.022 173.703 115.500 1.00 79.44  ? 65  LYS S N   1 
ATOM   5339 C CA  . LYS D 4 65  ? 127.056 173.015 116.783 1.00 79.64  ? 65  LYS S CA  1 
ATOM   5340 C C   . LYS D 4 65  ? 126.131 173.711 117.773 1.00 81.56  ? 65  LYS S C   1 
ATOM   5341 O O   . LYS D 4 65  ? 126.083 174.942 117.844 1.00 85.64  ? 65  LYS S O   1 
ATOM   5342 C CB  . LYS D 4 65  ? 128.486 172.982 117.321 1.00 81.18  ? 65  LYS S CB  1 
ATOM   5343 C CG  . LYS D 4 65  ? 128.633 172.517 118.762 1.00 83.93  ? 65  LYS S CG  1 
ATOM   5344 C CD  . LYS D 4 65  ? 127.992 171.161 118.990 1.00 83.35  ? 65  LYS S CD  1 
ATOM   5345 C CE  . LYS D 4 65  ? 128.892 170.269 119.826 1.00 83.98  ? 65  LYS S CE  1 
ATOM   5346 N NZ  . LYS D 4 65  ? 130.228 170.097 119.197 1.00 82.30  ? 65  LYS S NZ  1 
ATOM   5347 N N   . GLY D 4 66  ? 125.390 172.919 118.535 1.00 81.22  ? 66  GLY S N   1 
ATOM   5348 C CA  . GLY D 4 66  ? 124.479 173.472 119.535 1.00 84.84  ? 66  GLY S CA  1 
ATOM   5349 C C   . GLY D 4 66  ? 123.134 173.920 119.023 1.00 85.32  ? 66  GLY S C   1 
ATOM   5350 O O   . GLY D 4 66  ? 122.108 173.643 119.650 1.00 86.66  ? 66  GLY S O   1 
ATOM   5351 N N   . ARG D 4 67  ? 123.108 174.620 117.888 1.00 86.45  ? 67  ARG S N   1 
ATOM   5352 C CA  . ARG D 4 67  ? 121.839 175.073 117.331 1.00 84.82  ? 67  ARG S CA  1 
ATOM   5353 C C   . ARG D 4 67  ? 121.054 173.929 116.704 1.00 94.38  ? 67  ARG S C   1 
ATOM   5354 O O   . ARG D 4 67  ? 119.820 173.978 116.664 1.00 96.67  ? 67  ARG S O   1 
ATOM   5355 C CB  . ARG D 4 67  ? 122.083 176.168 116.296 1.00 84.53  ? 67  ARG S CB  1 
ATOM   5356 C CG  . ARG D 4 67  ? 122.480 177.502 116.885 1.00 90.56  ? 67  ARG S CG  1 
ATOM   5357 C CD  . ARG D 4 67  ? 122.821 178.497 115.794 1.00 94.11  ? 67  ARG S CD  1 
ATOM   5358 N NE  . ARG D 4 67  ? 123.759 177.947 114.824 1.00 92.85  ? 67  ARG S NE  1 
ATOM   5359 C CZ  . ARG D 4 67  ? 123.521 177.854 113.524 1.00 93.39  ? 67  ARG S CZ  1 
ATOM   5360 N NH1 . ARG D 4 67  ? 122.370 178.247 113.003 1.00 94.59  ? 67  ARG S NH1 1 
ATOM   5361 N NH2 . ARG D 4 67  ? 124.461 177.358 112.726 1.00 94.33  ? 67  ARG S NH2 1 
ATOM   5362 N N   . PHE D 4 68  ? 121.741 172.904 116.210 1.00 92.93  ? 68  PHE S N   1 
ATOM   5363 C CA  . PHE D 4 68  ? 121.120 171.818 115.468 1.00 84.32  ? 68  PHE S CA  1 
ATOM   5364 C C   . PHE D 4 68  ? 121.157 170.535 116.287 1.00 86.16  ? 68  PHE S C   1 
ATOM   5365 O O   . PHE D 4 68  ? 122.089 170.298 117.059 1.00 91.84  ? 68  PHE S O   1 
ATOM   5366 C CB  . PHE D 4 68  ? 121.830 171.585 114.131 1.00 82.95  ? 68  PHE S CB  1 
ATOM   5367 C CG  . PHE D 4 68  ? 121.550 172.636 113.091 1.00 86.25  ? 68  PHE S CG  1 
ATOM   5368 C CD1 . PHE D 4 68  ? 120.895 173.809 113.417 1.00 92.47  ? 68  PHE S CD1 1 
ATOM   5369 C CD2 . PHE D 4 68  ? 121.945 172.444 111.781 1.00 90.44  ? 68  PHE S CD2 1 
ATOM   5370 C CE1 . PHE D 4 68  ? 120.648 174.770 112.459 1.00 89.28  ? 68  PHE S CE1 1 
ATOM   5371 C CE2 . PHE D 4 68  ? 121.696 173.399 110.821 1.00 92.93  ? 68  PHE S CE2 1 
ATOM   5372 C CZ  . PHE D 4 68  ? 121.046 174.562 111.160 1.00 90.49  ? 68  PHE S CZ  1 
ATOM   5373 N N   . THR D 4 69  ? 120.127 169.707 116.115 1.00 92.55  ? 69  THR S N   1 
ATOM   5374 C CA  . THR D 4 69  ? 120.050 168.400 116.757 1.00 95.55  ? 69  THR S CA  1 
ATOM   5375 C C   . THR D 4 69  ? 119.595 167.382 115.724 1.00 92.31  ? 69  THR S C   1 
ATOM   5376 O O   . THR D 4 69  ? 118.483 167.485 115.199 1.00 95.18  ? 69  THR S O   1 
ATOM   5377 C CB  . THR D 4 69  ? 119.087 168.416 117.947 1.00 99.88  ? 69  THR S CB  1 
ATOM   5378 O OG1 . THR D 4 69  ? 117.820 168.937 117.530 1.00 104.40 ? 69  THR S OG1 1 
ATOM   5379 C CG2 . THR D 4 69  ? 119.639 169.272 119.077 1.00 96.16  ? 69  THR S CG2 1 
ATOM   5380 N N   . ILE D 4 70  ? 120.443 166.398 115.440 1.00 70.07  ? 70  ILE S N   1 
ATOM   5381 C CA  . ILE D 4 70  ? 120.153 165.367 114.451 1.00 70.62  ? 70  ILE S CA  1 
ATOM   5382 C C   . ILE D 4 70  ? 119.861 164.067 115.184 1.00 76.31  ? 70  ILE S C   1 
ATOM   5383 O O   . ILE D 4 70  ? 120.633 163.649 116.056 1.00 82.02  ? 70  ILE S O   1 
ATOM   5384 C CB  . ILE D 4 70  ? 121.313 165.199 113.455 1.00 74.52  ? 70  ILE S CB  1 
ATOM   5385 C CG1 . ILE D 4 70  ? 121.116 163.947 112.602 1.00 79.50  ? 70  ILE S CG1 1 
ATOM   5386 C CG2 . ILE D 4 70  ? 122.637 165.143 114.180 1.00 74.12  ? 70  ILE S CG2 1 
ATOM   5387 C CD1 . ILE D 4 70  ? 122.250 163.692 111.635 1.00 77.50  ? 70  ILE S CD1 1 
ATOM   5388 N N   . SER D 4 71  ? 118.741 163.436 114.842 1.00 82.06  ? 71  SER S N   1 
ATOM   5389 C CA  . SER D 4 71  ? 118.327 162.190 115.464 1.00 82.10  ? 71  SER S CA  1 
ATOM   5390 C C   . SER D 4 71  ? 117.696 161.297 114.408 1.00 87.58  ? 71  SER S C   1 
ATOM   5391 O O   . SER D 4 71  ? 117.520 161.691 113.253 1.00 94.95  ? 71  SER S O   1 
ATOM   5392 C CB  . SER D 4 71  ? 117.348 162.438 116.616 1.00 85.84  ? 71  SER S CB  1 
ATOM   5393 O OG  . SER D 4 71  ? 116.179 163.090 116.155 1.00 91.21  ? 71  SER S OG  1 
ATOM   5394 N N   . ARG D 4 72  ? 117.351 160.079 114.812 1.00 82.34  ? 72  ARG S N   1 
ATOM   5395 C CA  . ARG D 4 72  ? 116.749 159.119 113.903 1.00 80.05  ? 72  ARG S CA  1 
ATOM   5396 C C   . ARG D 4 72  ? 115.668 158.334 114.626 1.00 85.39  ? 72  ARG S C   1 
ATOM   5397 O O   . ARG D 4 72  ? 115.728 158.137 115.842 1.00 86.99  ? 72  ARG S O   1 
ATOM   5398 C CB  . ARG D 4 72  ? 117.793 158.156 113.336 1.00 81.69  ? 72  ARG S CB  1 
ATOM   5399 C CG  . ARG D 4 72  ? 118.532 157.372 114.395 1.00 79.39  ? 72  ARG S CG  1 
ATOM   5400 C CD  . ARG D 4 72  ? 119.860 156.877 113.874 1.00 79.84  ? 72  ARG S CD  1 
ATOM   5401 N NE  . ARG D 4 72  ? 119.777 156.455 112.483 1.00 80.13  ? 72  ARG S NE  1 
ATOM   5402 C CZ  . ARG D 4 72  ? 120.641 155.635 111.904 1.00 78.19  ? 72  ARG S CZ  1 
ATOM   5403 N NH1 . ARG D 4 72  ? 121.661 155.127 112.571 1.00 81.41  ? 72  ARG S NH1 1 
ATOM   5404 N NH2 . ARG D 4 72  ? 120.479 155.319 110.624 1.00 80.87  ? 72  ARG S NH2 1 
ATOM   5405 N N   . ASP D 4 73  ? 114.678 157.888 113.861 1.00 103.33 ? 73  ASP S N   1 
ATOM   5406 C CA  . ASP D 4 73  ? 113.616 157.011 114.340 1.00 103.81 ? 73  ASP S CA  1 
ATOM   5407 C C   . ASP D 4 73  ? 113.643 155.778 113.443 1.00 104.37 ? 73  ASP S C   1 
ATOM   5408 O O   . ASP D 4 73  ? 113.049 155.767 112.360 1.00 107.07 ? 73  ASP S O   1 
ATOM   5409 C CB  . ASP D 4 73  ? 112.264 157.711 114.316 1.00 107.21 ? 73  ASP S CB  1 
ATOM   5410 C CG  . ASP D 4 73  ? 111.317 157.180 115.372 1.00 110.45 ? 73  ASP S CG  1 
ATOM   5411 O OD1 . ASP D 4 73  ? 111.650 156.160 116.010 1.00 109.40 ? 73  ASP S OD1 1 
ATOM   5412 O OD2 . ASP D 4 73  ? 110.247 157.789 115.571 1.00 109.86 ? 73  ASP S OD2 1 
ATOM   5413 N N   . ASP D 4 74  ? 114.369 154.753 113.888 1.00 97.40  ? 74  ASP S N   1 
ATOM   5414 C CA  . ASP D 4 74  ? 114.490 153.525 113.104 1.00 97.45  ? 74  ASP S CA  1 
ATOM   5415 C C   . ASP D 4 74  ? 113.161 152.806 112.907 1.00 99.66  ? 74  ASP S C   1 
ATOM   5416 O O   . ASP D 4 74  ? 112.893 152.365 111.776 1.00 103.44 ? 74  ASP S O   1 
ATOM   5417 C CB  . ASP D 4 74  ? 115.534 152.608 113.748 1.00 98.09  ? 74  ASP S CB  1 
ATOM   5418 C CG  . ASP D 4 74  ? 116.904 153.242 113.807 1.00 101.58 ? 74  ASP S CG  1 
ATOM   5419 O OD1 . ASP D 4 74  ? 117.052 154.377 113.312 1.00 103.22 ? 74  ASP S OD1 1 
ATOM   5420 O OD2 . ASP D 4 74  ? 117.831 152.607 114.349 1.00 104.94 ? 74  ASP S OD2 1 
ATOM   5421 N N   . PRO D 4 75  ? 112.306 152.626 113.925 1.00 101.37 ? 75  PRO S N   1 
ATOM   5422 C CA  . PRO D 4 75  ? 111.027 151.939 113.667 1.00 102.85 ? 75  PRO S CA  1 
ATOM   5423 C C   . PRO D 4 75  ? 110.197 152.597 112.580 1.00 101.15 ? 75  PRO S C   1 
ATOM   5424 O O   . PRO D 4 75  ? 109.547 151.896 111.795 1.00 101.18 ? 75  PRO S O   1 
ATOM   5425 C CB  . PRO D 4 75  ? 110.306 151.982 115.023 1.00 104.77 ? 75  PRO S CB  1 
ATOM   5426 C CG  . PRO D 4 75  ? 111.210 152.665 115.976 1.00 103.68 ? 75  PRO S CG  1 
ATOM   5427 C CD  . PRO D 4 75  ? 112.555 152.803 115.367 1.00 102.97 ? 75  PRO S CD  1 
ATOM   5428 N N   . LYS D 4 76  ? 110.197 153.923 112.509 1.00 94.71  ? 76  LYS S N   1 
ATOM   5429 C CA  . LYS D 4 76  ? 109.494 154.630 111.450 1.00 95.93  ? 76  LYS S CA  1 
ATOM   5430 C C   . LYS D 4 76  ? 110.385 154.936 110.256 1.00 99.61  ? 76  LYS S C   1 
ATOM   5431 O O   . LYS D 4 76  ? 109.904 155.518 109.278 1.00 101.24 ? 76  LYS S O   1 
ATOM   5432 C CB  . LYS D 4 76  ? 108.886 155.927 111.989 1.00 96.86  ? 76  LYS S CB  1 
ATOM   5433 C CG  . LYS D 4 76  ? 107.851 155.711 113.079 1.00 97.34  ? 76  LYS S CG  1 
ATOM   5434 C CD  . LYS D 4 76  ? 107.671 156.954 113.932 1.00 102.37 ? 76  LYS S CD  1 
ATOM   5435 C CE  . LYS D 4 76  ? 107.490 158.197 113.075 1.00 104.05 ? 76  LYS S CE  1 
ATOM   5436 N NZ  . LYS D 4 76  ? 106.371 158.049 112.104 1.00 105.95 ? 76  LYS S NZ  1 
ATOM   5437 N N   . ASN D 4 77  ? 111.659 154.553 110.313 1.00 99.51  ? 77  ASN S N   1 
ATOM   5438 C CA  . ASN D 4 77  ? 112.608 154.746 109.219 1.00 98.63  ? 77  ASN S CA  1 
ATOM   5439 C C   . ASN D 4 77  ? 112.652 156.209 108.781 1.00 98.72  ? 77  ASN S C   1 
ATOM   5440 O O   . ASN D 4 77  ? 112.381 156.554 107.630 1.00 97.75  ? 77  ASN S O   1 
ATOM   5441 C CB  . ASN D 4 77  ? 112.272 153.830 108.039 1.00 96.27  ? 77  ASN S CB  1 
ATOM   5442 C CG  . ASN D 4 77  ? 112.989 152.499 108.113 1.00 100.87 ? 77  ASN S CG  1 
ATOM   5443 O OD1 . ASN D 4 77  ? 113.208 151.842 107.097 1.00 100.24 ? 77  ASN S OD1 1 
ATOM   5444 N ND2 . ASN D 4 77  ? 113.360 152.093 109.322 1.00 104.45 ? 77  ASN S ND2 1 
ATOM   5445 N N   . THR D 4 78  ? 112.999 157.075 109.729 1.00 103.57 ? 78  THR S N   1 
ATOM   5446 C CA  . THR D 4 78  ? 113.040 158.505 109.464 1.00 101.09 ? 78  THR S CA  1 
ATOM   5447 C C   . THR D 4 78  ? 114.295 159.106 110.077 1.00 103.48 ? 78  THR S C   1 
ATOM   5448 O O   . THR D 4 78  ? 114.811 158.613 111.081 1.00 102.64 ? 78  THR S O   1 
ATOM   5449 C CB  . THR D 4 78  ? 111.799 159.216 110.016 1.00 102.57 ? 78  THR S CB  1 
ATOM   5450 O OG1 . THR D 4 78  ? 110.660 158.355 109.890 1.00 106.74 ? 78  THR S OG1 1 
ATOM   5451 C CG2 . THR D 4 78  ? 111.534 160.500 109.249 1.00 101.66 ? 78  THR S CG2 1 
ATOM   5452 N N   . LEU D 4 79  ? 114.782 160.176 109.457 1.00 100.40 ? 79  LEU S N   1 
ATOM   5453 C CA  . LEU D 4 79  ? 115.928 160.927 109.954 1.00 95.85  ? 79  LEU S CA  1 
ATOM   5454 C C   . LEU D 4 79  ? 115.491 162.365 110.185 1.00 100.98 ? 79  LEU S C   1 
ATOM   5455 O O   . LEU D 4 79  ? 115.045 163.037 109.252 1.00 100.69 ? 79  LEU S O   1 
ATOM   5456 C CB  . LEU D 4 79  ? 117.092 160.856 108.965 1.00 89.17  ? 79  LEU S CB  1 
ATOM   5457 C CG  . LEU D 4 79  ? 118.129 161.973 109.008 1.00 92.15  ? 79  LEU S CG  1 
ATOM   5458 C CD1 . LEU D 4 79  ? 118.918 161.912 110.290 1.00 93.92  ? 79  LEU S CD1 1 
ATOM   5459 C CD2 . LEU D 4 79  ? 119.052 161.877 107.811 1.00 93.46  ? 79  LEU S CD2 1 
ATOM   5460 N N   . PHE D 4 80  ? 115.615 162.836 111.421 1.00 97.94  ? 80  PHE S N   1 
ATOM   5461 C CA  . PHE D 4 80  ? 115.112 164.141 111.816 1.00 89.71  ? 80  PHE S CA  1 
ATOM   5462 C C   . PHE D 4 80  ? 116.269 165.089 112.089 1.00 92.58  ? 80  PHE S C   1 
ATOM   5463 O O   . PHE D 4 80  ? 117.281 164.698 112.680 1.00 95.45  ? 80  PHE S O   1 
ATOM   5464 C CB  . PHE D 4 80  ? 114.235 164.029 113.063 1.00 85.87  ? 80  PHE S CB  1 
ATOM   5465 C CG  . PHE D 4 80  ? 112.902 163.398 112.809 1.00 88.72  ? 80  PHE S CG  1 
ATOM   5466 C CD1 . PHE D 4 80  ? 112.094 163.848 111.782 1.00 94.44  ? 80  PHE S CD1 1 
ATOM   5467 C CD2 . PHE D 4 80  ? 112.459 162.350 113.593 1.00 89.62  ? 80  PHE S CD2 1 
ATOM   5468 C CE1 . PHE D 4 80  ? 110.866 163.269 111.544 1.00 96.39  ? 80  PHE S CE1 1 
ATOM   5469 C CE2 . PHE D 4 80  ? 111.233 161.766 113.360 1.00 95.45  ? 80  PHE S CE2 1 
ATOM   5470 C CZ  . PHE D 4 80  ? 110.436 162.226 112.334 1.00 98.16  ? 80  PHE S CZ  1 
ATOM   5471 N N   . LEU D 4 81  ? 116.117 166.334 111.649 1.00 95.33  ? 81  LEU S N   1 
ATOM   5472 C CA  . LEU D 4 81  ? 117.052 167.404 111.977 1.00 91.64  ? 81  LEU S CA  1 
ATOM   5473 C C   . LEU D 4 81  ? 116.243 168.573 112.516 1.00 97.67  ? 81  LEU S C   1 
ATOM   5474 O O   . LEU D 4 81  ? 115.548 169.252 111.754 1.00 97.90  ? 81  LEU S O   1 
ATOM   5475 C CB  . LEU D 4 81  ? 117.873 167.823 110.760 1.00 93.04  ? 81  LEU S CB  1 
ATOM   5476 C CG  . LEU D 4 81  ? 118.954 168.870 111.029 1.00 93.20  ? 81  LEU S CG  1 
ATOM   5477 C CD1 . LEU D 4 81  ? 119.987 168.331 111.999 1.00 91.48  ? 81  LEU S CD1 1 
ATOM   5478 C CD2 . LEU D 4 81  ? 119.613 169.310 109.735 1.00 93.37  ? 81  LEU S CD2 1 
ATOM   5479 N N   . GLN D 4 82  ? 116.312 168.788 113.827 1.00 103.15 ? 82  GLN S N   1 
ATOM   5480 C CA  . GLN D 4 82  ? 115.644 169.909 114.472 1.00 99.12  ? 82  GLN S CA  1 
ATOM   5481 C C   . GLN D 4 82  ? 116.626 171.068 114.571 1.00 97.41  ? 82  GLN S C   1 
ATOM   5482 O O   . GLN D 4 82  ? 117.672 170.950 115.217 1.00 97.17  ? 82  GLN S O   1 
ATOM   5483 C CB  . GLN D 4 82  ? 115.133 169.518 115.856 1.00 97.49  ? 82  GLN S CB  1 
ATOM   5484 C CG  . GLN D 4 82  ? 114.425 170.642 116.589 1.00 101.36 ? 82  GLN S CG  1 
ATOM   5485 C CD  . GLN D 4 82  ? 112.918 170.548 116.480 1.00 105.22 ? 82  GLN S CD  1 
ATOM   5486 O OE1 . GLN D 4 82  ? 112.353 169.455 116.474 1.00 105.19 ? 82  GLN S OE1 1 
ATOM   5487 N NE2 . GLN D 4 82  ? 112.258 171.696 116.391 1.00 103.84 ? 82  GLN S NE2 1 
ATOM   5488 N N   . MET D 4 83  ? 116.288 172.182 113.935 1.00 98.92  ? 83  MET S N   1 
ATOM   5489 C CA  . MET D 4 83  ? 117.169 173.333 113.839 1.00 101.50 ? 83  MET S CA  1 
ATOM   5490 C C   . MET D 4 83  ? 116.531 174.516 114.548 1.00 105.04 ? 83  MET S C   1 
ATOM   5491 O O   . MET D 4 83  ? 115.350 174.811 114.334 1.00 106.59 ? 83  MET S O   1 
ATOM   5492 C CB  . MET D 4 83  ? 117.456 173.657 112.376 1.00 104.76 ? 83  MET S CB  1 
ATOM   5493 C CG  . MET D 4 83  ? 116.220 173.680 111.502 1.00 108.24 ? 83  MET S CG  1 
ATOM   5494 S SD  . MET D 4 83  ? 116.627 173.679 109.749 1.00 118.07 ? 83  MET S SD  1 
ATOM   5495 C CE  . MET D 4 83  ? 118.233 172.891 109.766 1.00 103.76 ? 83  MET S CE  1 
ATOM   5496 N N   . THR D 4 84  ? 117.308 175.180 115.399 1.00 101.64 ? 84  THR S N   1 
ATOM   5497 C CA  . THR D 4 84  ? 116.834 176.297 116.201 1.00 99.98  ? 84  THR S CA  1 
ATOM   5498 C C   . THR D 4 84  ? 117.694 177.522 115.936 1.00 100.50 ? 84  THR S C   1 
ATOM   5499 O O   . THR D 4 84  ? 118.913 177.413 115.776 1.00 101.37 ? 84  THR S O   1 
ATOM   5500 C CB  . THR D 4 84  ? 116.869 175.962 117.694 1.00 101.40 ? 84  THR S CB  1 
ATOM   5501 O OG1 . THR D 4 84  ? 118.226 175.765 118.106 1.00 101.71 ? 84  THR S OG1 1 
ATOM   5502 C CG2 . THR D 4 84  ? 116.071 174.700 117.977 1.00 103.77 ? 84  THR S CG2 1 
ATOM   5503 N N   . SER D 4 85  ? 117.048 178.689 115.895 1.00 103.79 ? 85  SER S N   1 
ATOM   5504 C CA  . SER D 4 85  ? 117.723 179.972 115.704 1.00 104.50 ? 85  SER S CA  1 
ATOM   5505 C C   . SER D 4 85  ? 118.511 179.989 114.393 1.00 106.86 ? 85  SER S C   1 
ATOM   5506 O O   . SER D 4 85  ? 119.739 180.087 114.370 1.00 105.45 ? 85  SER S O   1 
ATOM   5507 C CB  . SER D 4 85  ? 118.628 180.297 116.896 1.00 105.28 ? 85  SER S CB  1 
ATOM   5508 O OG  . SER D 4 85  ? 119.801 179.504 116.873 1.00 109.57 ? 85  SER S OG  1 
ATOM   5509 N N   . LEU D 4 86  ? 117.774 179.884 113.291 1.00 106.49 ? 86  LEU S N   1 
ATOM   5510 C CA  . LEU D 4 86  ? 118.389 179.908 111.970 1.00 103.86 ? 86  LEU S CA  1 
ATOM   5511 C C   . LEU D 4 86  ? 118.942 181.296 111.679 1.00 103.34 ? 86  LEU S C   1 
ATOM   5512 O O   . LEU D 4 86  ? 118.199 182.282 111.683 1.00 109.74 ? 86  LEU S O   1 
ATOM   5513 C CB  . LEU D 4 86  ? 117.383 179.505 110.893 1.00 104.96 ? 86  LEU S CB  1 
ATOM   5514 C CG  . LEU D 4 86  ? 116.623 178.178 110.988 1.00 108.22 ? 86  LEU S CG  1 
ATOM   5515 C CD1 . LEU D 4 86  ? 117.592 177.046 111.280 1.00 108.29 ? 86  LEU S CD1 1 
ATOM   5516 C CD2 . LEU D 4 86  ? 115.472 178.204 111.989 1.00 105.26 ? 86  LEU S CD2 1 
ATOM   5517 N N   . ARG D 4 87  ? 120.243 181.371 111.426 1.00 96.00  ? 87  ARG S N   1 
ATOM   5518 C CA  . ARG D 4 87  ? 120.871 182.622 111.028 1.00 99.14  ? 87  ARG S CA  1 
ATOM   5519 C C   . ARG D 4 87  ? 120.700 182.803 109.522 1.00 101.46 ? 87  ARG S C   1 
ATOM   5520 O O   . ARG D 4 87  ? 119.969 182.060 108.862 1.00 104.84 ? 87  ARG S O   1 
ATOM   5521 C CB  . ARG D 4 87  ? 122.334 182.638 111.459 1.00 102.85 ? 87  ARG S CB  1 
ATOM   5522 C CG  . ARG D 4 87  ? 122.567 182.078 112.850 1.00 104.73 ? 87  ARG S CG  1 
ATOM   5523 C CD  . ARG D 4 87  ? 123.822 181.226 112.900 1.00 104.10 ? 87  ARG S CD  1 
ATOM   5524 N NE  . ARG D 4 87  ? 125.033 182.035 112.872 1.00 106.87 ? 87  ARG S NE  1 
ATOM   5525 C CZ  . ARG D 4 87  ? 125.959 182.025 113.821 1.00 105.03 ? 87  ARG S CZ  1 
ATOM   5526 N NH1 . ARG D 4 87  ? 125.845 181.253 114.889 1.00 102.89 ? 87  ARG S NH1 1 
ATOM   5527 N NH2 . ARG D 4 87  ? 127.025 182.809 113.695 1.00 103.79 ? 87  ARG S NH2 1 
ATOM   5528 N N   . SER D 4 88  ? 121.379 183.802 108.956 1.00 109.50 ? 88  SER S N   1 
ATOM   5529 C CA  . SER D 4 88  ? 121.229 184.074 107.531 1.00 109.84 ? 88  SER S CA  1 
ATOM   5530 C C   . SER D 4 88  ? 121.889 183.003 106.674 1.00 109.08 ? 88  SER S C   1 
ATOM   5531 O O   . SER D 4 88  ? 121.426 182.733 105.560 1.00 111.86 ? 88  SER S O   1 
ATOM   5532 C CB  . SER D 4 88  ? 121.805 185.448 107.193 1.00 112.32 ? 88  SER S CB  1 
ATOM   5533 O OG  . SER D 4 88  ? 121.142 186.011 106.075 1.00 113.89 ? 88  SER S OG  1 
ATOM   5534 N N   . GLU D 4 89  ? 122.961 182.385 107.166 1.00 100.94 ? 89  GLU S N   1 
ATOM   5535 C CA  . GLU D 4 89  ? 123.700 181.413 106.372 1.00 101.50 ? 89  GLU S CA  1 
ATOM   5536 C C   . GLU D 4 89  ? 123.045 180.040 106.337 1.00 103.35 ? 89  GLU S C   1 
ATOM   5537 O O   . GLU D 4 89  ? 123.499 179.178 105.577 1.00 103.80 ? 89  GLU S O   1 
ATOM   5538 C CB  . GLU D 4 89  ? 125.159 181.358 106.872 1.00 101.56 ? 89  GLU S CB  1 
ATOM   5539 C CG  . GLU D 4 89  ? 125.449 180.991 108.354 1.00 106.46 ? 89  GLU S CG  1 
ATOM   5540 C CD  . GLU D 4 89  ? 124.898 179.663 108.868 1.00 113.32 ? 89  GLU S CD  1 
ATOM   5541 O OE1 . GLU D 4 89  ? 124.609 178.750 108.072 1.00 113.55 ? 89  GLU S OE1 1 
ATOM   5542 O OE2 . GLU D 4 89  ? 124.753 179.536 110.101 1.00 111.84 ? 89  GLU S OE2 1 
ATOM   5543 N N   . ASP D 4 90  ? 121.994 179.812 107.127 1.00 104.97 ? 90  ASP S N   1 
ATOM   5544 C CA  . ASP D 4 90  ? 121.336 178.510 107.132 1.00 103.01 ? 90  ASP S CA  1 
ATOM   5545 C C   . ASP D 4 90  ? 120.488 178.277 105.889 1.00 107.17 ? 90  ASP S C   1 
ATOM   5546 O O   . ASP D 4 90  ? 120.099 177.133 105.630 1.00 110.11 ? 90  ASP S O   1 
ATOM   5547 C CB  . ASP D 4 90  ? 120.470 178.359 108.382 1.00 107.25 ? 90  ASP S CB  1 
ATOM   5548 C CG  . ASP D 4 90  ? 121.273 177.965 109.605 1.00 111.63 ? 90  ASP S CG  1 
ATOM   5549 O OD1 . ASP D 4 90  ? 122.476 177.666 109.457 1.00 110.31 ? 90  ASP S OD1 1 
ATOM   5550 O OD2 . ASP D 4 90  ? 120.702 177.952 110.715 1.00 113.78 ? 90  ASP S OD2 1 
ATOM   5551 N N   . THR D 4 91  ? 120.185 179.325 105.125 1.00 107.52 ? 91  THR S N   1 
ATOM   5552 C CA  . THR D 4 91  ? 119.444 179.177 103.878 1.00 105.80 ? 91  THR S CA  1 
ATOM   5553 C C   . THR D 4 91  ? 120.250 178.327 102.905 1.00 106.13 ? 91  THR S C   1 
ATOM   5554 O O   . THR D 4 91  ? 121.309 178.757 102.437 1.00 106.84 ? 91  THR S O   1 
ATOM   5555 C CB  . THR D 4 91  ? 119.138 180.552 103.276 1.00 105.18 ? 91  THR S CB  1 
ATOM   5556 O OG1 . THR D 4 91  ? 118.059 181.160 103.996 1.00 107.03 ? 91  THR S OG1 1 
ATOM   5557 C CG2 . THR D 4 91  ? 118.758 180.437 101.805 1.00 105.72 ? 91  THR S CG2 1 
ATOM   5558 N N   . ALA D 4 92  ? 119.775 177.121 102.602 1.00 107.71 ? 92  ALA S N   1 
ATOM   5559 C CA  . ALA D 4 92  ? 120.580 176.202 101.809 1.00 108.18 ? 92  ALA S CA  1 
ATOM   5560 C C   . ALA D 4 92  ? 119.724 175.064 101.265 1.00 109.06 ? 92  ALA S C   1 
ATOM   5561 O O   . ALA D 4 92  ? 118.549 174.901 101.614 1.00 108.39 ? 92  ALA S O   1 
ATOM   5562 C CB  . ALA D 4 92  ? 121.745 175.641 102.629 1.00 107.32 ? 92  ALA S CB  1 
ATOM   5563 N N   . MET D 4 93  ? 120.351 174.294 100.379 1.00 108.34 ? 93  MET S N   1 
ATOM   5564 C CA  . MET D 4 93  ? 119.855 173.028 99.860  1.00 106.32 ? 93  MET S CA  1 
ATOM   5565 C C   . MET D 4 93  ? 120.324 171.927 100.806 1.00 106.17 ? 93  MET S C   1 
ATOM   5566 O O   . MET D 4 93  ? 121.531 171.755 100.998 1.00 106.49 ? 93  MET S O   1 
ATOM   5567 C CB  . MET D 4 93  ? 120.430 172.829 98.455  1.00 105.13 ? 93  MET S CB  1 
ATOM   5568 C CG  . MET D 4 93  ? 119.908 171.725 97.526  1.00 107.00 ? 93  MET S CG  1 
ATOM   5569 S SD  . MET D 4 93  ? 118.186 171.673 96.987  1.00 113.40 ? 93  MET S SD  1 
ATOM   5570 C CE  . MET D 4 93  ? 117.344 171.157 98.461  1.00 104.22 ? 93  MET S CE  1 
ATOM   5571 N N   . TYR D 4 94  ? 119.392 171.187 101.400 1.00 90.03  ? 94  TYR S N   1 
ATOM   5572 C CA  . TYR D 4 94  ? 119.726 170.202 102.422 1.00 86.43  ? 94  TYR S CA  1 
ATOM   5573 C C   . TYR D 4 94  ? 119.531 168.792 101.881 1.00 88.86  ? 94  TYR S C   1 
ATOM   5574 O O   . TYR D 4 94  ? 118.508 168.502 101.252 1.00 95.44  ? 94  TYR S O   1 
ATOM   5575 C CB  . TYR D 4 94  ? 118.875 170.413 103.675 1.00 84.12  ? 94  TYR S CB  1 
ATOM   5576 C CG  . TYR D 4 94  ? 119.447 171.435 104.630 1.00 88.76  ? 94  TYR S CG  1 
ATOM   5577 C CD1 . TYR D 4 94  ? 120.580 171.155 105.378 1.00 90.45  ? 94  TYR S CD1 1 
ATOM   5578 C CD2 . TYR D 4 94  ? 118.861 172.683 104.775 1.00 91.35  ? 94  TYR S CD2 1 
ATOM   5579 C CE1 . TYR D 4 94  ? 121.106 172.084 106.249 1.00 88.00  ? 94  TYR S CE1 1 
ATOM   5580 C CE2 . TYR D 4 94  ? 119.383 173.619 105.642 1.00 91.28  ? 94  TYR S CE2 1 
ATOM   5581 C CZ  . TYR D 4 94  ? 120.506 173.314 106.375 1.00 87.03  ? 94  TYR S CZ  1 
ATOM   5582 O OH  . TYR D 4 94  ? 121.029 174.243 107.242 1.00 90.18  ? 94  TYR S OH  1 
ATOM   5583 N N   . TYR D 4 95  ? 120.508 167.920 102.139 1.00 82.48  ? 95  TYR S N   1 
ATOM   5584 C CA  . TYR D 4 95  ? 120.505 166.546 101.663 1.00 80.67  ? 95  TYR S CA  1 
ATOM   5585 C C   . TYR D 4 95  ? 120.720 165.596 102.830 1.00 86.27  ? 95  TYR S C   1 
ATOM   5586 O O   . TYR D 4 95  ? 121.525 165.876 103.726 1.00 96.70  ? 95  TYR S O   1 
ATOM   5587 C CB  . TYR D 4 95  ? 121.616 166.306 100.637 1.00 82.21  ? 95  TYR S CB  1 
ATOM   5588 C CG  . TYR D 4 95  ? 121.556 167.158 99.394  1.00 85.05  ? 95  TYR S CG  1 
ATOM   5589 C CD1 . TYR D 4 95  ? 120.349 167.449 98.782  1.00 89.94  ? 95  TYR S CD1 1 
ATOM   5590 C CD2 . TYR D 4 95  ? 122.716 167.652 98.820  1.00 85.45  ? 95  TYR S CD2 1 
ATOM   5591 C CE1 . TYR D 4 95  ? 120.301 168.220 97.640  1.00 88.25  ? 95  TYR S CE1 1 
ATOM   5592 C CE2 . TYR D 4 95  ? 122.677 168.422 97.682  1.00 87.24  ? 95  TYR S CE2 1 
ATOM   5593 C CZ  . TYR D 4 95  ? 121.468 168.702 97.095  1.00 87.96  ? 95  TYR S CZ  1 
ATOM   5594 O OH  . TYR D 4 95  ? 121.428 169.470 95.956  1.00 91.52  ? 95  TYR S OH  1 
ATOM   5595 N N   . CYS D 4 96  ? 120.017 164.465 102.806 1.00 68.31  ? 96  CYS S N   1 
ATOM   5596 C CA  . CYS D 4 96  ? 120.325 163.340 103.677 1.00 71.48  ? 96  CYS S CA  1 
ATOM   5597 C C   . CYS D 4 96  ? 121.085 162.305 102.864 1.00 72.88  ? 96  CYS S C   1 
ATOM   5598 O O   . CYS D 4 96  ? 120.689 161.978 101.741 1.00 83.95  ? 96  CYS S O   1 
ATOM   5599 C CB  . CYS D 4 96  ? 119.069 162.708 104.276 1.00 79.61  ? 96  CYS S CB  1 
ATOM   5600 S SG  . CYS D 4 96  ? 117.651 162.623 103.185 1.00 104.81 ? 96  CYS S SG  1 
ATOM   5601 N N   . VAL D 4 97  ? 122.177 161.802 103.426 1.00 58.69  ? 97  VAL S N   1 
ATOM   5602 C CA  . VAL D 4 97  ? 123.056 160.863 102.746 1.00 55.18  ? 97  VAL S CA  1 
ATOM   5603 C C   . VAL D 4 97  ? 123.201 159.625 103.613 1.00 57.84  ? 97  VAL S C   1 
ATOM   5604 O O   . VAL D 4 97  ? 123.450 159.732 104.818 1.00 68.86  ? 97  VAL S O   1 
ATOM   5605 C CB  . VAL D 4 97  ? 124.438 161.478 102.466 1.00 61.38  ? 97  VAL S CB  1 
ATOM   5606 C CG1 . VAL D 4 97  ? 125.221 160.590 101.527 1.00 61.57  ? 97  VAL S CG1 1 
ATOM   5607 C CG2 . VAL D 4 97  ? 124.293 162.876 101.899 1.00 64.89  ? 97  VAL S CG2 1 
ATOM   5608 N N   . ARG D 4 98  ? 123.047 158.455 103.008 1.00 65.29  ? 98  ARG S N   1 
ATOM   5609 C CA  . ARG D 4 98  ? 123.335 157.219 103.711 1.00 63.08  ? 98  ARG S CA  1 
ATOM   5610 C C   . ARG D 4 98  ? 124.812 156.891 103.573 1.00 63.24  ? 98  ARG S C   1 
ATOM   5611 O O   . ARG D 4 98  ? 125.445 157.196 102.561 1.00 76.33  ? 98  ARG S O   1 
ATOM   5612 C CB  . ARG D 4 98  ? 122.493 156.060 103.179 1.00 66.15  ? 98  ARG S CB  1 
ATOM   5613 C CG  . ARG D 4 98  ? 122.068 156.189 101.736 1.00 68.11  ? 98  ARG S CG  1 
ATOM   5614 C CD  . ARG D 4 98  ? 121.516 154.867 101.233 1.00 71.57  ? 98  ARG S CD  1 
ATOM   5615 N NE  . ARG D 4 98  ? 122.577 153.932 100.881 1.00 72.79  ? 98  ARG S NE  1 
ATOM   5616 C CZ  . ARG D 4 98  ? 122.403 152.846 100.143 1.00 71.21  ? 98  ARG S CZ  1 
ATOM   5617 N NH1 . ARG D 4 98  ? 121.211 152.509 99.681  1.00 71.16  ? 98  ARG S NH1 1 
ATOM   5618 N NH2 . ARG D 4 98  ? 123.450 152.078 99.862  1.00 71.77  ? 98  ARG S NH2 1 
ATOM   5619 N N   . SER D 4 99  ? 125.362 156.269 104.613 1.00 50.57  ? 99  SER S N   1 
ATOM   5620 C CA  . SER D 4 99  ? 126.770 155.891 104.602 1.00 54.23  ? 99  SER S CA  1 
ATOM   5621 C C   . SER D 4 99  ? 126.931 154.725 105.574 1.00 58.05  ? 99  SER S C   1 
ATOM   5622 O O   . SER D 4 99  ? 126.863 154.920 106.789 1.00 68.57  ? 99  SER S O   1 
ATOM   5623 C CB  . SER D 4 99  ? 127.654 157.062 104.988 1.00 60.05  ? 99  SER S CB  1 
ATOM   5624 O OG  . SER D 4 99  ? 127.457 157.406 106.346 1.00 74.71  ? 99  SER S OG  1 
ATOM   5625 N N   . ILE D 4 100 ? 127.138 153.542 105.035 1.00 60.29  ? 100 ILE S N   1 
ATOM   5626 C CA  . ILE D 4 100 ? 127.416 152.366 105.845 1.00 58.69  ? 100 ILE S CA  1 
ATOM   5627 C C   . ILE D 4 100 ? 128.924 152.199 105.924 1.00 57.74  ? 100 ILE S C   1 
ATOM   5628 O O   . ILE D 4 100 ? 129.632 152.336 104.920 1.00 71.23  ? 100 ILE S O   1 
ATOM   5629 C CB  . ILE D 4 100 ? 126.723 151.118 105.267 1.00 61.55  ? 100 ILE S CB  1 
ATOM   5630 C CG1 . ILE D 4 100 ? 126.880 149.933 106.215 1.00 66.07  ? 100 ILE S CG1 1 
ATOM   5631 C CG2 . ILE D 4 100 ? 127.239 150.789 103.872 1.00 65.40  ? 100 ILE S CG2 1 
ATOM   5632 C CD1 . ILE D 4 100 ? 125.613 149.136 106.399 1.00 63.66  ? 100 ILE S CD1 1 
ATOM   5633 N N   . TYR D 4 101 ? 129.429 151.945 107.126 1.00 55.41  ? 101 TYR S N   1 
ATOM   5634 C CA  . TYR D 4 101 ? 130.864 151.948 107.380 1.00 63.85  ? 101 TYR S CA  1 
ATOM   5635 C C   . TYR D 4 101 ? 131.313 150.550 107.778 1.00 72.51  ? 101 TYR S C   1 
ATOM   5636 O O   . TYR D 4 101 ? 131.007 150.084 108.880 1.00 83.33  ? 101 TYR S O   1 
ATOM   5637 C CB  . TYR D 4 101 ? 131.224 152.963 108.461 1.00 64.11  ? 101 TYR S CB  1 
ATOM   5638 C CG  . TYR D 4 101 ? 130.884 154.390 108.105 1.00 66.80  ? 101 TYR S CG  1 
ATOM   5639 C CD1 . TYR D 4 101 ? 131.566 155.053 107.101 1.00 68.05  ? 101 TYR S CD1 1 
ATOM   5640 C CD2 . TYR D 4 101 ? 129.882 155.073 108.774 1.00 72.85  ? 101 TYR S CD2 1 
ATOM   5641 C CE1 . TYR D 4 101 ? 131.268 156.354 106.775 1.00 69.44  ? 101 TYR S CE1 1 
ATOM   5642 C CE2 . TYR D 4 101 ? 129.573 156.377 108.451 1.00 73.78  ? 101 TYR S CE2 1 
ATOM   5643 C CZ  . TYR D 4 101 ? 130.269 157.011 107.449 1.00 69.38  ? 101 TYR S CZ  1 
ATOM   5644 O OH  . TYR D 4 101 ? 129.967 158.311 107.120 1.00 75.85  ? 101 TYR S OH  1 
ATOM   5645 N N   . TYR D 4 102 ? 132.037 149.892 106.881 1.00 60.95  ? 102 TYR S N   1 
ATOM   5646 C CA  . TYR D 4 102 ? 132.729 148.646 107.178 1.00 55.41  ? 102 TYR S CA  1 
ATOM   5647 C C   . TYR D 4 102 ? 133.829 148.483 106.140 1.00 61.26  ? 102 TYR S C   1 
ATOM   5648 O O   . TYR D 4 102 ? 134.000 149.328 105.258 1.00 71.08  ? 102 TYR S O   1 
ATOM   5649 C CB  . TYR D 4 102 ? 131.770 147.452 107.200 1.00 62.56  ? 102 TYR S CB  1 
ATOM   5650 C CG  . TYR D 4 102 ? 130.929 147.269 105.957 1.00 61.04  ? 102 TYR S CG  1 
ATOM   5651 C CD1 . TYR D 4 102 ? 131.441 146.640 104.834 1.00 63.73  ? 102 TYR S CD1 1 
ATOM   5652 C CD2 . TYR D 4 102 ? 129.614 147.698 105.918 1.00 61.41  ? 102 TYR S CD2 1 
ATOM   5653 C CE1 . TYR D 4 102 ? 130.675 146.462 103.705 1.00 60.75  ? 102 TYR S CE1 1 
ATOM   5654 C CE2 . TYR D 4 102 ? 128.841 147.522 104.791 1.00 61.95  ? 102 TYR S CE2 1 
ATOM   5655 C CZ  . TYR D 4 102 ? 129.377 146.904 103.689 1.00 61.31  ? 102 TYR S CZ  1 
ATOM   5656 O OH  . TYR D 4 102 ? 128.608 146.728 102.564 1.00 64.54  ? 102 TYR S OH  1 
ATOM   5657 N N   . TYR D 4 103 ? 134.587 147.399 106.256 1.00 52.26  ? 103 TYR S N   1 
ATOM   5658 C CA  . TYR D 4 103 ? 135.688 147.182 105.329 1.00 52.14  ? 103 TYR S CA  1 
ATOM   5659 C C   . TYR D 4 103 ? 135.155 146.971 103.920 1.00 55.60  ? 103 TYR S C   1 
ATOM   5660 O O   . TYR D 4 103 ? 134.319 146.094 103.686 1.00 65.55  ? 103 TYR S O   1 
ATOM   5661 C CB  . TYR D 4 103 ? 136.528 145.986 105.762 1.00 49.38  ? 103 TYR S CB  1 
ATOM   5662 C CG  . TYR D 4 103 ? 137.654 145.697 104.803 1.00 50.06  ? 103 TYR S CG  1 
ATOM   5663 C CD1 . TYR D 4 103 ? 138.794 146.485 104.788 1.00 55.16  ? 103 TYR S CD1 1 
ATOM   5664 C CD2 . TYR D 4 103 ? 137.570 144.652 103.899 1.00 54.07  ? 103 TYR S CD2 1 
ATOM   5665 C CE1 . TYR D 4 103 ? 139.821 146.232 103.908 1.00 55.72  ? 103 TYR S CE1 1 
ATOM   5666 C CE2 . TYR D 4 103 ? 138.593 144.391 103.015 1.00 58.46  ? 103 TYR S CE2 1 
ATOM   5667 C CZ  . TYR D 4 103 ? 139.716 145.184 103.023 1.00 59.18  ? 103 TYR S CZ  1 
ATOM   5668 O OH  . TYR D 4 103 ? 140.739 144.926 102.142 1.00 69.05  ? 103 TYR S OH  1 
ATOM   5669 N N   . GLY D 4 104 ? 135.643 147.776 102.981 1.00 56.46  ? 104 GLY S N   1 
ATOM   5670 C CA  . GLY D 4 104 ? 135.207 147.680 101.606 1.00 59.61  ? 104 GLY S CA  1 
ATOM   5671 C C   . GLY D 4 104 ? 133.866 148.307 101.312 1.00 60.79  ? 104 GLY S C   1 
ATOM   5672 O O   . GLY D 4 104 ? 133.328 148.092 100.221 1.00 66.55  ? 104 GLY S O   1 
ATOM   5673 N N   . SER D 4 105 ? 133.308 149.074 102.242 1.00 58.76  ? 105 SER S N   1 
ATOM   5674 C CA  . SER D 4 105 ? 132.001 149.675 102.043 1.00 59.29  ? 105 SER S CA  1 
ATOM   5675 C C   . SER D 4 105 ? 132.113 150.906 101.149 1.00 69.74  ? 105 SER S C   1 
ATOM   5676 O O   . SER D 4 105 ? 133.199 151.299 100.714 1.00 77.89  ? 105 SER S O   1 
ATOM   5677 C CB  . SER D 4 105 ? 131.371 150.028 103.386 1.00 66.40  ? 105 SER S CB  1 
ATOM   5678 O OG  . SER D 4 105 ? 131.538 151.404 103.676 1.00 77.10  ? 105 SER S OG  1 
ATOM   5679 N N   . SER D 4 106 ? 130.970 151.530 100.875 1.00 66.36  ? 106 SER S N   1 
ATOM   5680 C CA  . SER D 4 106 ? 130.886 152.703 100.006 1.00 61.57  ? 106 SER S CA  1 
ATOM   5681 C C   . SER D 4 106 ? 130.157 153.809 100.754 1.00 66.14  ? 106 SER S C   1 
ATOM   5682 O O   . SER D 4 106 ? 128.951 154.013 100.564 1.00 73.04  ? 106 SER S O   1 
ATOM   5683 C CB  . SER D 4 106 ? 130.179 152.370 98.693  1.00 64.33  ? 106 SER S CB  1 
ATOM   5684 O OG  . SER D 4 106 ? 130.644 151.143 98.164  1.00 74.48  ? 106 SER S OG  1 
ATOM   5685 N N   . PRO D 4 107 ? 130.857 154.534 101.623 1.00 55.31  ? 107 PRO S N   1 
ATOM   5686 C CA  . PRO D 4 107 ? 130.222 155.650 102.327 1.00 56.14  ? 107 PRO S CA  1 
ATOM   5687 C C   . PRO D 4 107 ? 129.752 156.721 101.358 1.00 62.79  ? 107 PRO S C   1 
ATOM   5688 O O   . PRO D 4 107 ? 130.359 156.952 100.311 1.00 66.85  ? 107 PRO S O   1 
ATOM   5689 C CB  . PRO D 4 107 ? 131.338 156.173 103.238 1.00 56.75  ? 107 PRO S CB  1 
ATOM   5690 C CG  . PRO D 4 107 ? 132.262 155.016 103.394 1.00 59.48  ? 107 PRO S CG  1 
ATOM   5691 C CD  . PRO D 4 107 ? 132.241 154.322 102.073 1.00 60.69  ? 107 PRO S CD  1 
ATOM   5692 N N   . PHE D 4 108 ? 128.649 157.374 101.724 1.00 72.78  ? 108 PHE S N   1 
ATOM   5693 C CA  . PHE D 4 108 ? 128.042 158.426 100.910 1.00 68.27  ? 108 PHE S CA  1 
ATOM   5694 C C   . PHE D 4 108 ? 127.661 157.894 99.531  1.00 71.64  ? 108 PHE S C   1 
ATOM   5695 O O   . PHE D 4 108 ? 128.017 158.460 98.496  1.00 75.94  ? 108 PHE S O   1 
ATOM   5696 C CB  . PHE D 4 108 ? 128.965 159.641 100.804 1.00 68.91  ? 108 PHE S CB  1 
ATOM   5697 C CG  . PHE D 4 108 ? 129.083 160.420 102.079 1.00 70.36  ? 108 PHE S CG  1 
ATOM   5698 C CD1 . PHE D 4 108 ? 129.769 159.903 103.162 1.00 67.65  ? 108 PHE S CD1 1 
ATOM   5699 C CD2 . PHE D 4 108 ? 128.507 161.671 102.195 1.00 78.81  ? 108 PHE S CD2 1 
ATOM   5700 C CE1 . PHE D 4 108 ? 129.870 160.612 104.336 1.00 72.29  ? 108 PHE S CE1 1 
ATOM   5701 C CE2 . PHE D 4 108 ? 128.610 162.388 103.366 1.00 81.02  ? 108 PHE S CE2 1 
ATOM   5702 C CZ  . PHE D 4 108 ? 129.291 161.859 104.437 1.00 76.77  ? 108 PHE S CZ  1 
ATOM   5703 N N   . ASP D 4 109 ? 126.921 156.785 99.527  1.00 67.60  ? 109 ASP S N   1 
ATOM   5704 C CA  . ASP D 4 109 ? 126.567 156.122 98.279  1.00 64.45  ? 109 ASP S CA  1 
ATOM   5705 C C   . ASP D 4 109 ? 125.362 156.789 97.626  1.00 73.61  ? 109 ASP S C   1 
ATOM   5706 O O   . ASP D 4 109 ? 125.387 157.093 96.429  1.00 87.81  ? 109 ASP S O   1 
ATOM   5707 C CB  . ASP D 4 109 ? 126.300 154.637 98.545  1.00 69.79  ? 109 ASP S CB  1 
ATOM   5708 C CG  . ASP D 4 109 ? 125.348 154.009 97.538  1.00 90.10  ? 109 ASP S CG  1 
ATOM   5709 O OD1 . ASP D 4 109 ? 125.470 154.284 96.324  1.00 94.51  ? 109 ASP S OD1 1 
ATOM   5710 O OD2 . ASP D 4 109 ? 124.471 153.230 97.965  1.00 93.53  ? 109 ASP S OD2 1 
ATOM   5711 N N   . PHE D 4 110 ? 124.302 157.028 98.390  1.00 61.99  ? 110 PHE S N   1 
ATOM   5712 C CA  . PHE D 4 110 ? 123.063 157.572 97.856  1.00 65.91  ? 110 PHE S CA  1 
ATOM   5713 C C   . PHE D 4 110 ? 122.722 158.884 98.546  1.00 69.01  ? 110 PHE S C   1 
ATOM   5714 O O   . PHE D 4 110 ? 122.890 159.020 99.761  1.00 81.30  ? 110 PHE S O   1 
ATOM   5715 C CB  . PHE D 4 110 ? 121.907 156.586 98.022  1.00 75.09  ? 110 PHE S CB  1 
ATOM   5716 C CG  . PHE D 4 110 ? 120.682 156.959 97.245  1.00 78.88  ? 110 PHE S CG  1 
ATOM   5717 C CD1 . PHE D 4 110 ? 120.723 157.040 95.866  1.00 78.75  ? 110 PHE S CD1 1 
ATOM   5718 C CD2 . PHE D 4 110 ? 119.493 157.234 97.891  1.00 81.48  ? 110 PHE S CD2 1 
ATOM   5719 C CE1 . PHE D 4 110 ? 119.599 157.386 95.147  1.00 78.42  ? 110 PHE S CE1 1 
ATOM   5720 C CE2 . PHE D 4 110 ? 118.366 157.579 97.175  1.00 80.05  ? 110 PHE S CE2 1 
ATOM   5721 C CZ  . PHE D 4 110 ? 118.420 157.656 95.802  1.00 77.39  ? 110 PHE S CZ  1 
ATOM   5722 N N   . TRP D 4 111 ? 122.241 159.844 97.763  1.00 61.34  ? 111 TRP S N   1 
ATOM   5723 C CA  . TRP D 4 111 ? 121.866 161.158 98.257  1.00 67.39  ? 111 TRP S CA  1 
ATOM   5724 C C   . TRP D 4 111 ? 120.404 161.432 97.935  1.00 61.29  ? 111 TRP S C   1 
ATOM   5725 O O   . TRP D 4 111 ? 119.894 161.016 96.892  1.00 73.08  ? 111 TRP S O   1 
ATOM   5726 C CB  . TRP D 4 111 ? 122.736 162.256 97.640  1.00 77.61  ? 111 TRP S CB  1 
ATOM   5727 C CG  . TRP D 4 111 ? 124.163 162.258 98.082  1.00 75.55  ? 111 TRP S CG  1 
ATOM   5728 C CD1 . TRP D 4 111 ? 125.023 161.203 98.086  1.00 75.85  ? 111 TRP S CD1 1 
ATOM   5729 C CD2 . TRP D 4 111 ? 124.901 163.379 98.573  1.00 70.22  ? 111 TRP S CD2 1 
ATOM   5730 N NE1 . TRP D 4 111 ? 126.251 161.596 98.556  1.00 72.58  ? 111 TRP S NE1 1 
ATOM   5731 C CE2 . TRP D 4 111 ? 126.201 162.929 98.862  1.00 69.54  ? 111 TRP S CE2 1 
ATOM   5732 C CE3 . TRP D 4 111 ? 124.587 164.720 98.800  1.00 76.02  ? 111 TRP S CE3 1 
ATOM   5733 C CZ2 . TRP D 4 111 ? 127.184 163.770 99.367  1.00 74.99  ? 111 TRP S CZ2 1 
ATOM   5734 C CZ3 . TRP D 4 111 ? 125.564 165.553 99.300  1.00 78.02  ? 111 TRP S CZ3 1 
ATOM   5735 C CH2 . TRP D 4 111 ? 126.847 165.076 99.578  1.00 76.97  ? 111 TRP S CH2 1 
ATOM   5736 N N   . GLY D 4 112 ? 119.730 162.141 98.841  1.00 65.91  ? 112 GLY S N   1 
ATOM   5737 C CA  . GLY D 4 112 ? 118.339 162.489 98.654  1.00 72.77  ? 112 GLY S CA  1 
ATOM   5738 C C   . GLY D 4 112 ? 118.155 163.761 97.845  1.00 72.64  ? 112 GLY S C   1 
ATOM   5739 O O   . GLY D 4 112 ? 119.100 164.481 97.531  1.00 75.47  ? 112 GLY S O   1 
ATOM   5740 N N   . GLN D 4 113 ? 116.892 164.038 97.511  1.00 77.85  ? 113 GLN S N   1 
ATOM   5741 C CA  . GLN D 4 113 ? 116.578 165.224 96.720  1.00 78.48  ? 113 GLN S CA  1 
ATOM   5742 C C   . GLN D 4 113 ? 116.866 166.506 97.492  1.00 87.01  ? 113 GLN S C   1 
ATOM   5743 O O   . GLN D 4 113 ? 117.416 167.461 96.934  1.00 89.15  ? 113 GLN S O   1 
ATOM   5744 C CB  . GLN D 4 113 ? 115.118 165.184 96.272  1.00 84.12  ? 113 GLN S CB  1 
ATOM   5745 C CG  . GLN D 4 113 ? 114.781 164.229 95.115  1.00 90.92  ? 113 GLN S CG  1 
ATOM   5746 C CD  . GLN D 4 113 ? 115.914 164.006 94.118  1.00 91.98  ? 113 GLN S CD  1 
ATOM   5747 O OE1 . GLN D 4 113 ? 116.944 163.408 94.433  1.00 88.86  ? 113 GLN S OE1 1 
ATOM   5748 N NE2 . GLN D 4 113 ? 115.719 164.493 92.898  1.00 92.98  ? 113 GLN S NE2 1 
ATOM   5749 N N   . GLY D 4 114 ? 116.493 166.552 98.761  1.00 95.62  ? 114 GLY S N   1 
ATOM   5750 C CA  . GLY D 4 114 ? 116.818 167.664 99.627  1.00 94.88  ? 114 GLY S CA  1 
ATOM   5751 C C   . GLY D 4 114 ? 115.632 168.593 99.843  1.00 89.55  ? 114 GLY S C   1 
ATOM   5752 O O   . GLY D 4 114 ? 114.614 168.535 99.148  1.00 91.16  ? 114 GLY S O   1 
ATOM   5753 N N   . THR D 4 115 ? 115.784 169.469 100.834 1.00 92.80  ? 115 THR S N   1 
ATOM   5754 C CA  . THR D 4 115 ? 114.816 170.516 101.129 1.00 91.64  ? 115 THR S CA  1 
ATOM   5755 C C   . THR D 4 115 ? 115.481 171.876 100.995 1.00 97.04  ? 115 THR S C   1 
ATOM   5756 O O   . THR D 4 115 ? 116.627 172.062 101.417 1.00 99.15  ? 115 THR S O   1 
ATOM   5757 C CB  . THR D 4 115 ? 114.235 170.379 102.537 1.00 98.65  ? 115 THR S CB  1 
ATOM   5758 O OG1 . THR D 4 115 ? 115.275 170.562 103.506 1.00 103.07 ? 115 THR S OG1 1 
ATOM   5759 C CG2 . THR D 4 115 ? 113.598 169.023 102.726 1.00 100.29 ? 115 THR S CG2 1 
ATOM   5760 N N   . THR D 4 116 ? 114.770 172.817 100.385 1.00 100.89 ? 116 THR S N   1 
ATOM   5761 C CA  . THR D 4 116 ? 115.260 174.180 100.240 1.00 98.74  ? 116 THR S CA  1 
ATOM   5762 C C   . THR D 4 116 ? 114.786 174.997 101.433 1.00 100.16 ? 116 THR S C   1 
ATOM   5763 O O   . THR D 4 116 ? 113.577 175.132 101.657 1.00 102.65 ? 116 THR S O   1 
ATOM   5764 C CB  . THR D 4 116 ? 114.767 174.803 98.936  1.00 98.89  ? 116 THR S CB  1 
ATOM   5765 O OG1 . THR D 4 116 ? 113.368 175.089 99.044  1.00 102.19 ? 116 THR S OG1 1 
ATOM   5766 C CG2 . THR D 4 116 ? 114.993 173.853 97.774  1.00 102.70 ? 116 THR S CG2 1 
ATOM   5767 N N   . LEU D 4 117 ? 115.728 175.533 102.201 1.00 102.33 ? 117 LEU S N   1 
ATOM   5768 C CA  . LEU D 4 117 ? 115.408 176.374 103.344 1.00 100.95 ? 117 LEU S CA  1 
ATOM   5769 C C   . LEU D 4 117 ? 115.865 177.794 103.056 1.00 105.07 ? 117 LEU S C   1 
ATOM   5770 O O   . LEU D 4 117 ? 117.042 178.020 102.764 1.00 107.05 ? 117 LEU S O   1 
ATOM   5771 C CB  . LEU D 4 117 ? 116.073 175.854 104.616 1.00 99.82  ? 117 LEU S CB  1 
ATOM   5772 C CG  . LEU D 4 117 ? 115.486 176.436 105.898 1.00 103.23 ? 117 LEU S CG  1 
ATOM   5773 C CD1 . LEU D 4 117 ? 113.984 176.216 105.943 1.00 102.94 ? 117 LEU S CD1 1 
ATOM   5774 C CD2 . LEU D 4 117 ? 116.158 175.833 107.106 1.00 104.41 ? 117 LEU S CD2 1 
ATOM   5775 N N   . THR D 4 118 ? 114.941 178.746 103.144 1.00 112.34 ? 118 THR S N   1 
ATOM   5776 C CA  . THR D 4 118 ? 115.232 180.146 102.871 1.00 111.96 ? 118 THR S CA  1 
ATOM   5777 C C   . THR D 4 118 ? 114.820 180.971 104.078 1.00 114.67 ? 118 THR S C   1 
ATOM   5778 O O   . THR D 4 118 ? 113.651 180.945 104.480 1.00 116.31 ? 118 THR S O   1 
ATOM   5779 C CB  . THR D 4 118 ? 114.501 180.628 101.616 1.00 113.23 ? 118 THR S CB  1 
ATOM   5780 O OG1 . THR D 4 118 ? 113.194 180.044 101.572 1.00 114.85 ? 118 THR S OG1 1 
ATOM   5781 C CG2 . THR D 4 118 ? 115.270 180.227 100.369 1.00 111.63 ? 118 THR S CG2 1 
ATOM   5782 N N   . VAL D 4 119 ? 115.771 181.702 104.647 1.00 115.46 ? 119 VAL S N   1 
ATOM   5783 C CA  . VAL D 4 119 ? 115.510 182.587 105.772 1.00 115.11 ? 119 VAL S CA  1 
ATOM   5784 C C   . VAL D 4 119 ? 115.584 184.026 105.284 1.00 116.42 ? 119 VAL S C   1 
ATOM   5785 O O   . VAL D 4 119 ? 116.325 184.353 104.350 1.00 116.90 ? 119 VAL S O   1 
ATOM   5786 C CB  . VAL D 4 119 ? 116.491 182.340 106.938 1.00 114.75 ? 119 VAL S CB  1 
ATOM   5787 C CG1 . VAL D 4 119 ? 116.301 180.943 107.498 1.00 114.02 ? 119 VAL S CG1 1 
ATOM   5788 C CG2 . VAL D 4 119 ? 117.926 182.540 106.486 1.00 113.95 ? 119 VAL S CG2 1 
ATOM   5789 N N   . SER D 4 120 ? 114.782 184.885 105.904 1.00 121.88 ? 120 SER S N   1 
ATOM   5790 C CA  . SER D 4 120 ? 114.800 186.297 105.556 1.00 122.21 ? 120 SER S CA  1 
ATOM   5791 C C   . SER D 4 120 ? 116.063 186.957 106.093 1.00 123.58 ? 120 SER S C   1 
ATOM   5792 O O   . SER D 4 120 ? 116.516 186.660 107.201 1.00 124.81 ? 120 SER S O   1 
ATOM   5793 C CB  . SER D 4 120 ? 113.559 186.997 106.108 1.00 123.17 ? 120 SER S CB  1 
ATOM   5794 O OG  . SER D 4 120 ? 112.387 186.538 105.456 1.00 122.34 ? 120 SER S OG  1 
ATOM   5795 N N   . SER D 4 121 ? 116.631 187.858 105.299 1.00 123.23 ? 121 SER S N   1 
ATOM   5796 C CA  . SER D 4 121 ? 117.858 188.544 105.684 1.00 121.04 ? 121 SER S CA  1 
ATOM   5797 C C   . SER D 4 121 ? 117.600 189.565 106.788 1.00 120.27 ? 121 SER S C   1 
ATOM   5798 O O   . SER D 4 121 ? 116.462 189.762 107.212 1.00 121.67 ? 121 SER S O   1 
ATOM   5799 C CB  . SER D 4 121 ? 118.489 189.229 104.472 1.00 121.74 ? 121 SER S CB  1 
ATOM   5800 O OG  . SER D 4 121 ? 118.574 188.337 103.375 1.00 124.46 ? 121 SER S OG  1 
ATOM   5801 N N   . SER D 4 136 ? 142.544 173.733 112.266 1.00 100.94 ? 124 SER S N   1 
ATOM   5802 C CA  . SER D 4 136 ? 141.853 172.571 112.810 1.00 104.38 ? 124 SER S CA  1 
ATOM   5803 C C   . SER D 4 136 ? 141.228 171.736 111.699 1.00 107.44 ? 124 SER S C   1 
ATOM   5804 O O   . SER D 4 136 ? 141.688 170.633 111.406 1.00 107.34 ? 124 SER S O   1 
ATOM   5805 C CB  . SER D 4 136 ? 140.782 173.007 113.811 1.00 103.22 ? 124 SER S CB  1 
ATOM   5806 O OG  . SER D 4 136 ? 139.934 173.994 113.251 1.00 105.86 ? 124 SER S OG  1 
ATOM   5807 N N   . ASP D 4 137 ? 140.175 172.270 111.087 1.00 112.36 ? 125 ASP S N   1 
ATOM   5808 C CA  . ASP D 4 137 ? 139.510 171.573 109.996 1.00 107.90 ? 125 ASP S CA  1 
ATOM   5809 C C   . ASP D 4 137 ? 140.417 171.497 108.776 1.00 107.49 ? 125 ASP S C   1 
ATOM   5810 O O   . ASP D 4 137 ? 141.184 172.421 108.493 1.00 110.74 ? 125 ASP S O   1 
ATOM   5811 C CB  . ASP D 4 137 ? 138.206 172.279 109.631 1.00 108.07 ? 125 ASP S CB  1 
ATOM   5812 C CG  . ASP D 4 137 ? 137.324 172.530 110.834 1.00 113.99 ? 125 ASP S CG  1 
ATOM   5813 O OD1 . ASP D 4 137 ? 137.807 173.143 111.809 1.00 116.13 ? 125 ASP S OD1 1 
ATOM   5814 O OD2 . ASP D 4 137 ? 136.146 172.117 110.806 1.00 116.34 ? 125 ASP S OD2 1 
ATOM   5815 N N   . ILE D 4 138 ? 140.330 170.382 108.051 1.00 89.33  ? 126 ILE S N   1 
ATOM   5816 C CA  . ILE D 4 138 ? 141.069 170.251 106.804 1.00 89.76  ? 126 ILE S CA  1 
ATOM   5817 C C   . ILE D 4 138 ? 140.411 171.117 105.738 1.00 90.61  ? 126 ILE S C   1 
ATOM   5818 O O   . ILE D 4 138 ? 139.185 171.277 105.702 1.00 91.26  ? 126 ILE S O   1 
ATOM   5819 C CB  . ILE D 4 138 ? 141.137 168.778 106.361 1.00 88.75  ? 126 ILE S CB  1 
ATOM   5820 C CG1 . ILE D 4 138 ? 141.440 167.879 107.558 1.00 89.52  ? 126 ILE S CG1 1 
ATOM   5821 C CG2 . ILE D 4 138 ? 142.189 168.596 105.280 1.00 92.58  ? 126 ILE S CG2 1 
ATOM   5822 C CD1 . ILE D 4 138 ? 141.994 166.528 107.184 1.00 92.65  ? 126 ILE S CD1 1 
ATOM   5823 N N   . VAL D 4 139 ? 141.231 171.691 104.863 1.00 96.94  ? 127 VAL S N   1 
ATOM   5824 C CA  . VAL D 4 139 ? 140.752 172.543 103.783 1.00 96.86  ? 127 VAL S CA  1 
ATOM   5825 C C   . VAL D 4 139 ? 140.972 171.824 102.459 1.00 99.98  ? 127 VAL S C   1 
ATOM   5826 O O   . VAL D 4 139 ? 141.972 171.120 102.275 1.00 102.72 ? 127 VAL S O   1 
ATOM   5827 C CB  . VAL D 4 139 ? 141.435 173.926 103.798 1.00 96.42  ? 127 VAL S CB  1 
ATOM   5828 C CG1 . VAL D 4 139 ? 141.471 174.478 105.213 1.00 95.96  ? 127 VAL S CG1 1 
ATOM   5829 C CG2 . VAL D 4 139 ? 142.840 173.858 103.221 1.00 95.61  ? 127 VAL S CG2 1 
ATOM   5830 N N   . MET D 4 140 ? 140.007 171.966 101.554 1.00 98.31  ? 128 MET S N   1 
ATOM   5831 C CA  . MET D 4 140 ? 140.067 171.374 100.225 1.00 96.42  ? 128 MET S CA  1 
ATOM   5832 C C   . MET D 4 140 ? 140.042 172.493 99.198  1.00 100.60 ? 128 MET S C   1 
ATOM   5833 O O   . MET D 4 140 ? 139.090 173.279 99.155  1.00 104.10 ? 128 MET S O   1 
ATOM   5834 C CB  . MET D 4 140 ? 138.905 170.406 100.002 1.00 95.33  ? 128 MET S CB  1 
ATOM   5835 C CG  . MET D 4 140 ? 139.021 169.132 100.808 1.00 95.31  ? 128 MET S CG  1 
ATOM   5836 S SD  . MET D 4 140 ? 140.388 168.119 100.228 1.00 98.76  ? 128 MET S SD  1 
ATOM   5837 C CE  . MET D 4 140 ? 140.879 167.339 101.754 1.00 96.26  ? 128 MET S CE  1 
ATOM   5838 N N   . THR D 4 141 ? 141.081 172.563 98.374  1.00 101.89 ? 129 THR S N   1 
ATOM   5839 C CA  . THR D 4 141 ? 141.229 173.619 97.383  1.00 103.18 ? 129 THR S CA  1 
ATOM   5840 C C   . THR D 4 141 ? 141.126 173.016 95.991  1.00 100.33 ? 129 THR S C   1 
ATOM   5841 O O   . THR D 4 141 ? 141.847 172.066 95.666  1.00 99.28  ? 129 THR S O   1 
ATOM   5842 C CB  . THR D 4 141 ? 142.563 174.346 97.551  1.00 103.90 ? 129 THR S CB  1 
ATOM   5843 O OG1 . THR D 4 141 ? 143.578 173.664 96.805  1.00 104.30 ? 129 THR S OG1 1 
ATOM   5844 C CG2 . THR D 4 141 ? 142.966 174.391 99.017  1.00 103.42 ? 129 THR S CG2 1 
ATOM   5845 N N   . GLN D 4 142 ? 140.231 173.565 95.176  1.00 98.88  ? 130 GLN S N   1 
ATOM   5846 C CA  . GLN D 4 142 ? 140.104 173.211 93.764  1.00 98.54  ? 130 GLN S CA  1 
ATOM   5847 C C   . GLN D 4 142 ? 140.272 174.496 92.963  1.00 101.65 ? 130 GLN S C   1 
ATOM   5848 O O   . GLN D 4 142 ? 139.294 175.152 92.599  1.00 100.60 ? 130 GLN S O   1 
ATOM   5849 C CB  . GLN D 4 142 ? 138.773 172.543 93.474  1.00 96.25  ? 130 GLN S CB  1 
ATOM   5850 C CG  . GLN D 4 142 ? 138.313 171.572 94.537  1.00 95.20  ? 130 GLN S CG  1 
ATOM   5851 C CD  . GLN D 4 142 ? 137.454 170.468 93.963  1.00 97.84  ? 130 GLN S CD  1 
ATOM   5852 O OE1 . GLN D 4 142 ? 136.547 170.720 93.172  1.00 98.19  ? 130 GLN S OE1 1 
ATOM   5853 N NE2 . GLN D 4 142 ? 137.741 169.235 94.350  1.00 100.67 ? 130 GLN S NE2 1 
ATOM   5854 N N   . ALA D 4 143 ? 141.526 174.849 92.681  1.00 121.92 ? 131 ALA S N   1 
ATOM   5855 C CA  . ALA D 4 143 ? 141.809 176.067 91.935  1.00 121.89 ? 131 ALA S CA  1 
ATOM   5856 C C   . ALA D 4 143 ? 141.397 175.968 90.475  1.00 121.19 ? 131 ALA S C   1 
ATOM   5857 O O   . ALA D 4 143 ? 141.387 176.991 89.782  1.00 123.27 ? 131 ALA S O   1 
ATOM   5858 C CB  . ALA D 4 143 ? 143.296 176.409 92.031  1.00 118.59 ? 131 ALA S CB  1 
ATOM   5859 N N   . THR D 4 144 ? 141.066 174.769 89.995  1.00 121.09 ? 132 THR S N   1 
ATOM   5860 C CA  . THR D 4 144 ? 140.689 174.608 88.595  1.00 124.77 ? 132 THR S CA  1 
ATOM   5861 C C   . THR D 4 144 ? 139.397 175.354 88.283  1.00 124.99 ? 132 THR S C   1 
ATOM   5862 O O   . THR D 4 144 ? 139.292 176.022 87.248  1.00 124.83 ? 132 THR S O   1 
ATOM   5863 C CB  . THR D 4 144 ? 140.553 173.123 88.266  1.00 125.38 ? 132 THR S CB  1 
ATOM   5864 O OG1 . THR D 4 144 ? 141.812 172.472 88.478  1.00 125.20 ? 132 THR S OG1 1 
ATOM   5865 C CG2 . THR D 4 144 ? 140.162 172.941 86.815  1.00 121.58 ? 132 THR S CG2 1 
ATOM   5866 N N   . SER D 4 145 ? 138.409 175.260 89.174  1.00 112.18 ? 133 SER S N   1 
ATOM   5867 C CA  . SER D 4 145 ? 137.114 175.948 89.056  1.00 107.32 ? 133 SER S CA  1 
ATOM   5868 C C   . SER D 4 145 ? 136.481 175.562 87.718  1.00 113.46 ? 133 SER S C   1 
ATOM   5869 O O   . SER D 4 145 ? 136.482 174.374 87.369  1.00 117.25 ? 133 SER S O   1 
ATOM   5870 C CB  . SER D 4 145 ? 137.321 177.438 89.280  1.00 103.49 ? 133 SER S CB  1 
ATOM   5871 O OG  . SER D 4 145 ? 137.870 177.684 90.561  1.00 106.99 ? 133 SER S OG  1 
ATOM   5872 N N   . SER D 4 146 ? 135.942 176.507 86.951  1.00 111.92 ? 134 SER S N   1 
ATOM   5873 C CA  . SER D 4 146 ? 135.256 176.169 85.712  1.00 112.98 ? 134 SER S CA  1 
ATOM   5874 C C   . SER D 4 146 ? 136.252 175.804 84.619  1.00 115.74 ? 134 SER S C   1 
ATOM   5875 O O   . SER D 4 146 ? 137.296 176.443 84.466  1.00 115.42 ? 134 SER S O   1 
ATOM   5876 C CB  . SER D 4 146 ? 134.385 177.338 85.257  1.00 111.68 ? 134 SER S CB  1 
ATOM   5877 O OG  . SER D 4 146 ? 133.719 177.033 84.045  1.00 114.08 ? 134 SER S OG  1 
ATOM   5878 N N   . VAL D 4 147 ? 135.920 174.768 83.852  1.00 113.94 ? 135 VAL S N   1 
ATOM   5879 C CA  . VAL D 4 147 ? 136.763 174.301 82.753  1.00 110.54 ? 135 VAL S CA  1 
ATOM   5880 C C   . VAL D 4 147 ? 135.892 173.948 81.554  1.00 112.38 ? 135 VAL S C   1 
ATOM   5881 O O   . VAL D 4 147 ? 134.902 173.218 81.701  1.00 109.88 ? 135 VAL S O   1 
ATOM   5882 C CB  . VAL D 4 147 ? 137.616 173.095 83.174  1.00 109.09 ? 135 VAL S CB  1 
ATOM   5883 C CG1 . VAL D 4 147 ? 138.266 172.456 81.958  1.00 109.80 ? 135 VAL S CG1 1 
ATOM   5884 C CG2 . VAL D 4 147 ? 138.676 173.519 84.162  1.00 108.81 ? 135 VAL S CG2 1 
ATOM   5885 N N   . PRO D 4 148 ? 136.213 174.438 80.358  1.00 123.89 ? 136 PRO S N   1 
ATOM   5886 C CA  . PRO D 4 148 ? 135.474 174.005 79.167  1.00 122.66 ? 136 PRO S CA  1 
ATOM   5887 C C   . PRO D 4 148 ? 135.913 172.615 78.733  1.00 123.98 ? 136 PRO S C   1 
ATOM   5888 O O   . PRO D 4 148 ? 137.105 172.299 78.707  1.00 122.24 ? 136 PRO S O   1 
ATOM   5889 C CB  . PRO D 4 148 ? 135.840 175.063 78.122  1.00 121.45 ? 136 PRO S CB  1 
ATOM   5890 C CG  . PRO D 4 148 ? 137.204 175.515 78.532  1.00 122.81 ? 136 PRO S CG  1 
ATOM   5891 C CD  . PRO D 4 148 ? 137.241 175.445 80.039  1.00 122.10 ? 136 PRO S CD  1 
ATOM   5892 N N   . VAL D 4 149 ? 134.934 171.782 78.391  1.00 128.78 ? 137 VAL S N   1 
ATOM   5893 C CA  . VAL D 4 149 ? 135.179 170.396 78.011  1.00 129.65 ? 137 VAL S CA  1 
ATOM   5894 C C   . VAL D 4 149 ? 134.435 170.094 76.719  1.00 126.49 ? 137 VAL S C   1 
ATOM   5895 O O   . VAL D 4 149 ? 133.330 170.599 76.492  1.00 125.73 ? 137 VAL S O   1 
ATOM   5896 C CB  . VAL D 4 149 ? 134.757 169.412 79.124  1.00 131.79 ? 137 VAL S CB  1 
ATOM   5897 C CG1 . VAL D 4 149 ? 135.670 169.550 80.333  1.00 129.46 ? 137 VAL S CG1 1 
ATOM   5898 C CG2 . VAL D 4 149 ? 133.306 169.636 79.519  1.00 128.59 ? 137 VAL S CG2 1 
ATOM   5899 N N   . THR D 4 150 ? 135.052 169.276 75.869  1.00 121.41 ? 138 THR S N   1 
ATOM   5900 C CA  . THR D 4 150 ? 134.446 168.808 74.634  1.00 122.43 ? 138 THR S CA  1 
ATOM   5901 C C   . THR D 4 150 ? 134.191 167.314 74.727  1.00 121.96 ? 138 THR S C   1 
ATOM   5902 O O   . THR D 4 150 ? 135.070 166.574 75.187  1.00 120.92 ? 138 THR S O   1 
ATOM   5903 C CB  . THR D 4 150 ? 135.353 169.106 73.436  1.00 121.80 ? 138 THR S CB  1 
ATOM   5904 O OG1 . THR D 4 150 ? 136.600 168.420 73.598  1.00 124.47 ? 138 THR S OG1 1 
ATOM   5905 C CG2 . THR D 4 150 ? 135.613 170.600 73.324  1.00 119.89 ? 138 THR S CG2 1 
ATOM   5906 N N   . PRO D 4 151 ? 133.018 166.835 74.313  1.00 111.72 ? 139 PRO S N   1 
ATOM   5907 C CA  . PRO D 4 151 ? 132.717 165.405 74.452  1.00 109.79 ? 139 PRO S CA  1 
ATOM   5908 C C   . PRO D 4 151 ? 133.722 164.544 73.701  1.00 109.05 ? 139 PRO S C   1 
ATOM   5909 O O   . PRO D 4 151 ? 134.151 164.876 72.594  1.00 109.59 ? 139 PRO S O   1 
ATOM   5910 C CB  . PRO D 4 151 ? 131.309 165.276 73.857  1.00 105.76 ? 139 PRO S CB  1 
ATOM   5911 C CG  . PRO D 4 151 ? 131.108 166.512 73.044  1.00 107.91 ? 139 PRO S CG  1 
ATOM   5912 C CD  . PRO D 4 151 ? 131.901 167.583 73.715  1.00 109.00 ? 139 PRO S CD  1 
ATOM   5913 N N   . GLY D 4 152 ? 134.098 163.429 74.322  1.00 112.68 ? 140 GLY S N   1 
ATOM   5914 C CA  . GLY D 4 152 ? 135.059 162.507 73.766  1.00 111.78 ? 140 GLY S CA  1 
ATOM   5915 C C   . GLY D 4 152 ? 136.485 162.727 74.227  1.00 113.00 ? 140 GLY S C   1 
ATOM   5916 O O   . GLY D 4 152 ? 137.313 161.820 74.083  1.00 115.30 ? 140 GLY S O   1 
ATOM   5917 N N   . GLU D 4 153 ? 136.791 163.897 74.778  1.00 113.41 ? 141 GLU S N   1 
ATOM   5918 C CA  . GLU D 4 153 ? 138.134 164.184 75.252  1.00 114.77 ? 141 GLU S CA  1 
ATOM   5919 C C   . GLU D 4 153 ? 138.349 163.587 76.641  1.00 116.49 ? 141 GLU S C   1 
ATOM   5920 O O   . GLU D 4 153 ? 137.419 163.115 77.298  1.00 117.67 ? 141 GLU S O   1 
ATOM   5921 C CB  . GLU D 4 153 ? 138.382 165.692 75.267  1.00 115.84 ? 141 GLU S CB  1 
ATOM   5922 C CG  . GLU D 4 153 ? 137.938 166.386 76.544  1.00 118.06 ? 141 GLU S CG  1 
ATOM   5923 C CD  . GLU D 4 153 ? 138.137 167.888 76.489  1.00 118.91 ? 141 GLU S CD  1 
ATOM   5924 O OE1 . GLU D 4 153 ? 138.473 168.405 75.403  1.00 120.31 ? 141 GLU S OE1 1 
ATOM   5925 O OE2 . GLU D 4 153 ? 137.957 168.553 77.532  1.00 116.43 ? 141 GLU S OE2 1 
ATOM   5926 N N   . SER D 4 154 ? 139.603 163.599 77.082  1.00 98.56  ? 142 SER S N   1 
ATOM   5927 C CA  . SER D 4 154 ? 139.983 163.124 78.406  1.00 99.98  ? 142 SER S CA  1 
ATOM   5928 C C   . SER D 4 154 ? 140.349 164.325 79.264  1.00 103.46 ? 142 SER S C   1 
ATOM   5929 O O   . SER D 4 154 ? 141.239 165.101 78.900  1.00 101.72 ? 142 SER S O   1 
ATOM   5930 C CB  . SER D 4 154 ? 141.153 162.145 78.323  1.00 99.99  ? 142 SER S CB  1 
ATOM   5931 O OG  . SER D 4 154 ? 142.297 162.773 77.770  1.00 100.26 ? 142 SER S OG  1 
ATOM   5932 N N   . VAL D 4 155 ? 139.669 164.477 80.400  1.00 109.35 ? 143 VAL S N   1 
ATOM   5933 C CA  . VAL D 4 155 ? 139.870 165.634 81.260  1.00 106.69 ? 143 VAL S CA  1 
ATOM   5934 C C   . VAL D 4 155 ? 140.341 165.149 82.626  1.00 101.07 ? 143 VAL S C   1 
ATOM   5935 O O   . VAL D 4 155 ? 140.132 163.997 83.014  1.00 102.98 ? 143 VAL S O   1 
ATOM   5936 C CB  . VAL D 4 155 ? 138.590 166.489 81.391  1.00 104.66 ? 143 VAL S CB  1 
ATOM   5937 C CG1 . VAL D 4 155 ? 137.552 165.769 82.226  1.00 104.07 ? 143 VAL S CG1 1 
ATOM   5938 C CG2 . VAL D 4 155 ? 138.898 167.873 81.952  1.00 102.54 ? 143 VAL S CG2 1 
ATOM   5939 N N   . SER D 4 156 ? 141.000 166.048 83.352  1.00 96.04  ? 144 SER S N   1 
ATOM   5940 C CA  . SER D 4 156 ? 141.500 165.768 84.690  1.00 100.59 ? 144 SER S CA  1 
ATOM   5941 C C   . SER D 4 156 ? 141.080 166.893 85.623  1.00 106.01 ? 144 SER S C   1 
ATOM   5942 O O   . SER D 4 156 ? 141.190 168.071 85.268  1.00 107.37 ? 144 SER S O   1 
ATOM   5943 C CB  . SER D 4 156 ? 143.024 165.615 84.690  1.00 100.29 ? 144 SER S CB  1 
ATOM   5944 O OG  . SER D 4 156 ? 143.513 165.377 85.997  1.00 104.80 ? 144 SER S OG  1 
ATOM   5945 N N   . ILE D 4 157 ? 140.599 166.527 86.807  1.00 98.62  ? 145 ILE S N   1 
ATOM   5946 C CA  . ILE D 4 157 ? 140.195 167.474 87.839  1.00 91.04  ? 145 ILE S CA  1 
ATOM   5947 C C   . ILE D 4 157 ? 141.095 167.266 89.046  1.00 95.08  ? 145 ILE S C   1 
ATOM   5948 O O   . ILE D 4 157 ? 141.239 166.138 89.530  1.00 99.22  ? 145 ILE S O   1 
ATOM   5949 C CB  . ILE D 4 157 ? 138.716 167.296 88.219  1.00 88.28  ? 145 ILE S CB  1 
ATOM   5950 C CG1 . ILE D 4 157 ? 137.812 167.746 87.074  1.00 94.37  ? 145 ILE S CG1 1 
ATOM   5951 C CG2 . ILE D 4 157 ? 138.401 168.057 89.492  1.00 96.46  ? 145 ILE S CG2 1 
ATOM   5952 C CD1 . ILE D 4 157 ? 138.113 169.139 86.575  1.00 100.15 ? 145 ILE S CD1 1 
ATOM   5953 N N   . SER D 4 158 ? 141.692 168.346 89.536  1.00 99.74  ? 146 SER S N   1 
ATOM   5954 C CA  . SER D 4 158 ? 142.659 168.278 90.621  1.00 101.85 ? 146 SER S CA  1 
ATOM   5955 C C   . SER D 4 158 ? 142.032 168.754 91.923  1.00 104.05 ? 146 SER S C   1 
ATOM   5956 O O   . SER D 4 158 ? 141.309 169.755 91.947  1.00 109.07 ? 146 SER S O   1 
ATOM   5957 C CB  . SER D 4 158 ? 143.896 169.119 90.303  1.00 103.25 ? 146 SER S CB  1 
ATOM   5958 O OG  . SER D 4 158 ? 143.556 170.486 90.157  1.00 106.92 ? 146 SER S OG  1 
ATOM   5959 N N   . CYS D 4 159 ? 142.310 168.028 93.001  1.00 103.89 ? 147 CYS S N   1 
ATOM   5960 C CA  . CYS D 4 159 ? 141.886 168.399 94.342  1.00 103.97 ? 147 CYS S CA  1 
ATOM   5961 C C   . CYS D 4 159 ? 143.112 168.402 95.242  1.00 105.88 ? 147 CYS S C   1 
ATOM   5962 O O   . CYS D 4 159 ? 144.057 167.640 95.017  1.00 105.99 ? 147 CYS S O   1 
ATOM   5963 C CB  . CYS D 4 159 ? 140.812 167.433 94.874  1.00 105.99 ? 147 CYS S CB  1 
ATOM   5964 S SG  . CYS D 4 159 ? 140.332 167.660 96.606  1.00 123.62 ? 147 CYS S SG  1 
ATOM   5965 N N   . ARG D 4 160 ? 143.116 169.279 96.240  1.00 101.10 ? 148 ARG S N   1 
ATOM   5966 C CA  . ARG D 4 160 ? 144.272 169.440 97.107  1.00 98.97  ? 148 ARG S CA  1 
ATOM   5967 C C   . ARG D 4 160 ? 143.834 169.412 98.562  1.00 101.99 ? 148 ARG S C   1 
ATOM   5968 O O   . ARG D 4 160 ? 142.790 169.966 98.916  1.00 102.36 ? 148 ARG S O   1 
ATOM   5969 C CB  . ARG D 4 160 ? 145.011 170.744 96.798  1.00 99.43  ? 148 ARG S CB  1 
ATOM   5970 C CG  . ARG D 4 160 ? 146.229 171.007 97.680  1.00 101.39 ? 148 ARG S CG  1 
ATOM   5971 C CD  . ARG D 4 160 ? 147.003 172.289 97.303  1.00 103.59 ? 148 ARG S CD  1 
ATOM   5972 N NE  . ARG D 4 160 ? 147.088 172.670 95.890  1.00 105.04 ? 148 ARG S NE  1 
ATOM   5973 C CZ  . ARG D 4 160 ? 147.274 171.860 94.852  1.00 105.33 ? 148 ARG S CZ  1 
ATOM   5974 N NH1 . ARG D 4 160 ? 147.561 170.576 95.007  1.00 105.97 ? 148 ARG S NH1 1 
ATOM   5975 N NH2 . ARG D 4 160 ? 147.217 172.362 93.623  1.00 103.73 ? 148 ARG S NH2 1 
ATOM   5976 N N   . SER D 4 161 ? 144.639 168.768 99.400  1.00 105.54 ? 149 SER S N   1 
ATOM   5977 C CA  . SER D 4 161 ? 144.352 168.621 100.817 1.00 106.15 ? 149 SER S CA  1 
ATOM   5978 C C   . SER D 4 161 ? 145.351 169.421 101.641 1.00 105.60 ? 149 SER S C   1 
ATOM   5979 O O   . SER D 4 161 ? 146.517 169.569 101.263 1.00 107.43 ? 149 SER S O   1 
ATOM   5980 C CB  . SER D 4 161 ? 144.395 167.150 101.238 1.00 106.82 ? 149 SER S CB  1 
ATOM   5981 O OG  . SER D 4 161 ? 145.721 166.651 101.212 1.00 110.82 ? 149 SER S OG  1 
ATOM   5982 N N   . SER D 4 162 ? 144.877 169.943 102.774 1.00 94.08  ? 150 SER S N   1 
ATOM   5983 C CA  . SER D 4 162 ? 145.759 170.685 103.668 1.00 94.10  ? 150 SER S CA  1 
ATOM   5984 C C   . SER D 4 162 ? 146.868 169.794 104.211 1.00 95.09  ? 150 SER S C   1 
ATOM   5985 O O   . SER D 4 162 ? 148.031 170.208 104.282 1.00 97.01  ? 150 SER S O   1 
ATOM   5986 C CB  . SER D 4 162 ? 144.953 171.296 104.812 1.00 95.36  ? 150 SER S CB  1 
ATOM   5987 O OG  . SER D 4 162 ? 145.804 171.938 105.745 1.00 100.96 ? 150 SER S OG  1 
ATOM   5988 N N   . LYS D 4 163 ? 146.530 168.568 104.597 1.00 92.89  ? 151 LYS S N   1 
ATOM   5989 C CA  . LYS D 4 163 ? 147.498 167.607 105.099 1.00 92.68  ? 151 LYS S CA  1 
ATOM   5990 C C   . LYS D 4 163 ? 147.241 166.253 104.457 1.00 94.08  ? 151 LYS S C   1 
ATOM   5991 O O   . LYS D 4 163 ? 146.181 166.012 103.874 1.00 97.66  ? 151 LYS S O   1 
ATOM   5992 C CB  . LYS D 4 163 ? 147.441 167.497 106.628 1.00 92.18  ? 151 LYS S CB  1 
ATOM   5993 C CG  . LYS D 4 163 ? 146.536 166.396 107.149 1.00 90.69  ? 151 LYS S CG  1 
ATOM   5994 C CD  . LYS D 4 163 ? 146.500 166.404 108.665 1.00 92.50  ? 151 LYS S CD  1 
ATOM   5995 C CE  . LYS D 4 163 ? 145.115 166.088 109.191 1.00 94.23  ? 151 LYS S CE  1 
ATOM   5996 N NZ  . LYS D 4 163 ? 145.186 165.340 110.473 1.00 94.02  ? 151 LYS S NZ  1 
ATOM   5997 N N   . SER D 4 164 ? 148.232 165.371 104.562 1.00 100.35 ? 152 SER S N   1 
ATOM   5998 C CA  . SER D 4 164 ? 148.139 164.057 103.940 1.00 100.42 ? 152 SER S CA  1 
ATOM   5999 C C   . SER D 4 164 ? 146.954 163.284 104.502 1.00 101.02 ? 152 SER S C   1 
ATOM   6000 O O   . SER D 4 164 ? 146.742 163.244 105.717 1.00 102.21 ? 152 SER S O   1 
ATOM   6001 C CB  . SER D 4 164 ? 149.429 163.273 104.162 1.00 100.38 ? 152 SER S CB  1 
ATOM   6002 O OG  . SER D 4 164 ? 149.594 162.950 105.532 1.00 101.94 ? 152 SER S OG  1 
ATOM   6003 N N   . LEU D 4 165 ? 146.179 162.674 103.610 1.00 87.30  ? 153 LEU S N   1 
ATOM   6004 C CA  . LEU D 4 165 ? 145.011 161.894 103.988 1.00 85.77  ? 153 LEU S CA  1 
ATOM   6005 C C   . LEU D 4 165 ? 145.265 160.395 103.955 1.00 90.09  ? 153 LEU S C   1 
ATOM   6006 O O   . LEU D 4 165 ? 144.322 159.617 104.121 1.00 92.06  ? 153 LEU S O   1 
ATOM   6007 C CB  . LEU D 4 165 ? 143.837 162.245 103.077 1.00 82.99  ? 153 LEU S CB  1 
ATOM   6008 C CG  . LEU D 4 165 ? 143.414 163.702 103.249 1.00 91.69  ? 153 LEU S CG  1 
ATOM   6009 C CD1 . LEU D 4 165 ? 142.266 164.035 102.339 1.00 90.08  ? 153 LEU S CD1 1 
ATOM   6010 C CD2 . LEU D 4 165 ? 143.056 163.995 104.696 1.00 92.69  ? 153 LEU S CD2 1 
ATOM   6011 N N   . LEU D 4 166 ? 146.507 159.976 103.742 1.00 86.94  ? 154 LEU S N   1 
ATOM   6012 C CA  . LEU D 4 166 ? 146.868 158.562 103.738 1.00 78.67  ? 154 LEU S CA  1 
ATOM   6013 C C   . LEU D 4 166 ? 147.036 158.108 105.181 1.00 85.27  ? 154 LEU S C   1 
ATOM   6014 O O   . LEU D 4 166 ? 148.086 158.316 105.792 1.00 89.89  ? 154 LEU S O   1 
ATOM   6015 C CB  . LEU D 4 166 ? 148.143 158.340 102.933 1.00 75.21  ? 154 LEU S CB  1 
ATOM   6016 C CG  . LEU D 4 166 ? 148.512 156.906 102.561 1.00 80.61  ? 154 LEU S CG  1 
ATOM   6017 C CD1 . LEU D 4 166 ? 149.111 156.867 101.168 1.00 86.82  ? 154 LEU S CD1 1 
ATOM   6018 C CD2 . LEU D 4 166 ? 149.482 156.322 103.571 1.00 84.22  ? 154 LEU S CD2 1 
ATOM   6019 N N   . HIS D 4 167 ? 145.998 157.489 105.732 1.00 88.40  ? 155 HIS S N   1 
ATOM   6020 C CA  . HIS D 4 167 ? 146.080 156.961 107.083 1.00 83.70  ? 155 HIS S CA  1 
ATOM   6021 C C   . HIS D 4 167 ? 147.070 155.801 107.134 1.00 90.03  ? 155 HIS S C   1 
ATOM   6022 O O   . HIS D 4 167 ? 147.390 155.174 106.121 1.00 92.63  ? 155 HIS S O   1 
ATOM   6023 C CB  . HIS D 4 167 ? 144.700 156.514 107.564 1.00 77.62  ? 155 HIS S CB  1 
ATOM   6024 C CG  . HIS D 4 167 ? 144.566 156.446 109.053 1.00 79.20  ? 155 HIS S CG  1 
ATOM   6025 N ND1 . HIS D 4 167 ? 143.709 157.261 109.759 1.00 88.26  ? 155 HIS S ND1 1 
ATOM   6026 C CD2 . HIS D 4 167 ? 145.154 155.640 109.968 1.00 85.71  ? 155 HIS S CD2 1 
ATOM   6027 C CE1 . HIS D 4 167 ? 143.792 156.978 111.046 1.00 92.92  ? 155 HIS S CE1 1 
ATOM   6028 N NE2 . HIS D 4 167 ? 144.661 155.995 111.200 1.00 92.88  ? 155 HIS S NE2 1 
ATOM   6029 N N   . SER D 4 168 ? 147.570 155.528 108.341 1.00 91.52  ? 156 SER S N   1 
ATOM   6030 C CA  . SER D 4 168 ? 148.547 154.463 108.527 1.00 91.02  ? 156 SER S CA  1 
ATOM   6031 C C   . SER D 4 168 ? 148.005 153.097 108.130 1.00 95.45  ? 156 SER S C   1 
ATOM   6032 O O   . SER D 4 168 ? 148.794 152.187 107.859 1.00 97.41  ? 156 SER S O   1 
ATOM   6033 C CB  . SER D 4 168 ? 149.013 154.432 109.982 1.00 90.40  ? 156 SER S CB  1 
ATOM   6034 O OG  . SER D 4 168 ? 149.463 155.709 110.398 1.00 93.50  ? 156 SER S OG  1 
ATOM   6035 N N   . ASN D 4 169 ? 146.681 152.930 108.086 1.00 91.71  ? 157 ASN S N   1 
ATOM   6036 C CA  . ASN D 4 169 ? 146.107 151.656 107.673 1.00 82.86  ? 157 ASN S CA  1 
ATOM   6037 C C   . ASN D 4 169 ? 146.276 151.387 106.184 1.00 85.49  ? 157 ASN S C   1 
ATOM   6038 O O   . ASN D 4 169 ? 145.990 150.271 105.739 1.00 91.63  ? 157 ASN S O   1 
ATOM   6039 C CB  . ASN D 4 169 ? 144.624 151.597 108.047 1.00 84.14  ? 157 ASN S CB  1 
ATOM   6040 C CG  . ASN D 4 169 ? 143.845 152.797 107.552 1.00 93.17  ? 157 ASN S CG  1 
ATOM   6041 O OD1 . ASN D 4 169 ? 144.222 153.440 106.573 1.00 93.31  ? 157 ASN S OD1 1 
ATOM   6042 N ND2 . ASN D 4 169 ? 142.745 153.103 108.227 1.00 97.26  ? 157 ASN S ND2 1 
ATOM   6043 N N   . GLY D 4 170 ? 146.728 152.368 105.411 1.00 82.84  ? 158 GLY S N   1 
ATOM   6044 C CA  . GLY D 4 170 ? 146.963 152.187 103.997 1.00 86.18  ? 158 GLY S CA  1 
ATOM   6045 C C   . GLY D 4 170 ? 145.896 152.733 103.078 1.00 88.99  ? 158 GLY S C   1 
ATOM   6046 O O   . GLY D 4 170 ? 146.012 152.564 101.859 1.00 90.38  ? 158 GLY S O   1 
ATOM   6047 N N   . ASN D 4 171 ? 144.870 153.383 103.613 1.00 80.48  ? 159 ASN S N   1 
ATOM   6048 C CA  . ASN D 4 171 ? 143.785 153.927 102.814 1.00 73.04  ? 159 ASN S CA  1 
ATOM   6049 C C   . ASN D 4 171 ? 143.935 155.433 102.667 1.00 80.31  ? 159 ASN S C   1 
ATOM   6050 O O   . ASN D 4 171 ? 144.387 156.124 103.583 1.00 89.62  ? 159 ASN S O   1 
ATOM   6051 C CB  . ASN D 4 171 ? 142.425 153.614 103.442 1.00 72.63  ? 159 ASN S CB  1 
ATOM   6052 C CG  . ASN D 4 171 ? 142.255 152.149 103.761 1.00 83.63  ? 159 ASN S CG  1 
ATOM   6053 O OD1 . ASN D 4 171 ? 143.150 151.341 103.523 1.00 94.62  ? 159 ASN S OD1 1 
ATOM   6054 N ND2 . ASN D 4 171 ? 141.098 151.796 104.304 1.00 82.91  ? 159 ASN S ND2 1 
ATOM   6055 N N   . THR D 4 172 ? 143.562 155.934 101.495 1.00 72.42  ? 160 THR S N   1 
ATOM   6056 C CA  . THR D 4 172 ? 143.421 157.360 101.261 1.00 76.00  ? 160 THR S CA  1 
ATOM   6057 C C   . THR D 4 172 ? 141.935 157.678 101.167 1.00 80.74  ? 160 THR S C   1 
ATOM   6058 O O   . THR D 4 172 ? 141.137 156.839 100.743 1.00 88.99  ? 160 THR S O   1 
ATOM   6059 C CB  . THR D 4 172 ? 144.149 157.792 99.992  1.00 81.72  ? 160 THR S CB  1 
ATOM   6060 O OG1 . THR D 4 172 ? 145.474 157.252 99.998  1.00 87.65  ? 160 THR S OG1 1 
ATOM   6061 C CG2 . THR D 4 172 ? 144.247 159.296 99.945  1.00 88.11  ? 160 THR S CG2 1 
ATOM   6062 N N   . TYR D 4 173 ? 141.560 158.889 101.565 1.00 71.60  ? 161 TYR S N   1 
ATOM   6063 C CA  . TYR D 4 173 ? 140.204 159.120 102.041 1.00 70.59  ? 161 TYR S CA  1 
ATOM   6064 C C   . TYR D 4 173 ? 139.523 160.257 101.290 1.00 75.49  ? 161 TYR S C   1 
ATOM   6065 O O   . TYR D 4 173 ? 138.916 161.144 101.893 1.00 77.90  ? 161 TYR S O   1 
ATOM   6066 C CB  . TYR D 4 173 ? 140.234 159.423 103.530 1.00 74.23  ? 161 TYR S CB  1 
ATOM   6067 C CG  . TYR D 4 173 ? 140.435 158.202 104.385 1.00 74.57  ? 161 TYR S CG  1 
ATOM   6068 C CD1 . TYR D 4 173 ? 141.695 157.643 104.533 1.00 81.08  ? 161 TYR S CD1 1 
ATOM   6069 C CD2 . TYR D 4 173 ? 139.386 157.626 105.068 1.00 69.59  ? 161 TYR S CD2 1 
ATOM   6070 C CE1 . TYR D 4 173 ? 141.895 156.533 105.322 1.00 85.47  ? 161 TYR S CE1 1 
ATOM   6071 C CE2 . TYR D 4 173 ? 139.583 156.519 105.850 1.00 69.00  ? 161 TYR S CE2 1 
ATOM   6072 C CZ  . TYR D 4 173 ? 140.831 155.975 105.979 1.00 79.50  ? 161 TYR S CZ  1 
ATOM   6073 O OH  . TYR D 4 173 ? 141.011 154.865 106.770 1.00 81.70  ? 161 TYR S OH  1 
ATOM   6074 N N   . LEU D 4 174 ? 139.601 160.261 99.964  1.00 76.37  ? 162 LEU S N   1 
ATOM   6075 C CA  . LEU D 4 174 ? 138.760 161.149 99.173  1.00 71.23  ? 162 LEU S CA  1 
ATOM   6076 C C   . LEU D 4 174 ? 137.494 160.439 98.735  1.00 75.19  ? 162 LEU S C   1 
ATOM   6077 O O   . LEU D 4 174 ? 137.490 159.229 98.494  1.00 84.18  ? 162 LEU S O   1 
ATOM   6078 C CB  . LEU D 4 174 ? 139.447 161.690 97.923  1.00 73.99  ? 162 LEU S CB  1 
ATOM   6079 C CG  . LEU D 4 174 ? 140.304 162.945 98.007  1.00 77.95  ? 162 LEU S CG  1 
ATOM   6080 C CD1 . LEU D 4 174 ? 141.174 162.976 99.241  1.00 80.09  ? 162 LEU S CD1 1 
ATOM   6081 C CD2 . LEU D 4 174 ? 141.091 163.099 96.744  1.00 75.51  ? 162 LEU S CD2 1 
ATOM   6082 N N   . TYR D 4 175 ? 136.421 161.209 98.638  1.00 73.12  ? 163 TYR S N   1 
ATOM   6083 C CA  . TYR D 4 175 ? 135.182 160.787 98.010  1.00 76.22  ? 163 TYR S CA  1 
ATOM   6084 C C   . TYR D 4 175 ? 134.822 161.851 96.985  1.00 81.43  ? 163 TYR S C   1 
ATOM   6085 O O   . TYR D 4 175 ? 134.687 163.032 97.330  1.00 87.34  ? 163 TYR S O   1 
ATOM   6086 C CB  . TYR D 4 175 ? 134.067 160.603 99.040  1.00 77.11  ? 163 TYR S CB  1 
ATOM   6087 C CG  . TYR D 4 175 ? 134.324 159.497 100.039 1.00 70.30  ? 163 TYR S CG  1 
ATOM   6088 C CD1 . TYR D 4 175 ? 135.318 159.616 100.995 1.00 70.17  ? 163 TYR S CD1 1 
ATOM   6089 C CD2 . TYR D 4 175 ? 133.580 158.330 100.018 1.00 74.40  ? 163 TYR S CD2 1 
ATOM   6090 C CE1 . TYR D 4 175 ? 135.559 158.615 101.903 1.00 75.13  ? 163 TYR S CE1 1 
ATOM   6091 C CE2 . TYR D 4 175 ? 133.815 157.321 100.924 1.00 78.95  ? 163 TYR S CE2 1 
ATOM   6092 C CZ  . TYR D 4 175 ? 134.805 157.470 101.865 1.00 79.08  ? 163 TYR S CZ  1 
ATOM   6093 O OH  . TYR D 4 175 ? 135.047 156.468 102.772 1.00 87.85  ? 163 TYR S OH  1 
ATOM   6094 N N   . TRP D 4 176 ? 134.709 161.439 95.728  1.00 73.74  ? 164 TRP S N   1 
ATOM   6095 C CA  . TRP D 4 176 ? 134.348 162.334 94.643  1.00 67.20  ? 164 TRP S CA  1 
ATOM   6096 C C   . TRP D 4 176 ? 132.853 162.251 94.385  1.00 70.27  ? 164 TRP S C   1 
ATOM   6097 O O   . TRP D 4 176 ? 132.274 161.163 94.357  1.00 80.85  ? 164 TRP S O   1 
ATOM   6098 C CB  . TRP D 4 176 ? 135.109 161.981 93.366  1.00 73.91  ? 164 TRP S CB  1 
ATOM   6099 C CG  . TRP D 4 176 ? 136.561 162.316 93.402  1.00 77.13  ? 164 TRP S CG  1 
ATOM   6100 C CD1 . TRP D 4 176 ? 137.580 161.499 93.784  1.00 79.99  ? 164 TRP S CD1 1 
ATOM   6101 C CD2 . TRP D 4 176 ? 137.163 163.558 93.026  1.00 73.16  ? 164 TRP S CD2 1 
ATOM   6102 N NE1 . TRP D 4 176 ? 138.780 162.155 93.675  1.00 75.03  ? 164 TRP S NE1 1 
ATOM   6103 C CE2 . TRP D 4 176 ? 138.549 163.423 93.212  1.00 72.87  ? 164 TRP S CE2 1 
ATOM   6104 C CE3 . TRP D 4 176 ? 136.661 164.773 92.555  1.00 74.96  ? 164 TRP S CE3 1 
ATOM   6105 C CZ2 . TRP D 4 176 ? 139.441 164.454 92.943  1.00 80.43  ? 164 TRP S CZ2 1 
ATOM   6106 C CZ3 . TRP D 4 176 ? 137.547 165.795 92.288  1.00 80.11  ? 164 TRP S CZ3 1 
ATOM   6107 C CH2 . TRP D 4 176 ? 138.920 165.630 92.482  1.00 82.10  ? 164 TRP S CH2 1 
ATOM   6108 N N   . PHE D 4 177 ? 132.235 163.409 94.194  1.00 74.25  ? 165 PHE S N   1 
ATOM   6109 C CA  . PHE D 4 177 ? 130.809 163.489 93.932  1.00 76.54  ? 165 PHE S CA  1 
ATOM   6110 C C   . PHE D 4 177 ? 130.573 164.320 92.682  1.00 83.16  ? 165 PHE S C   1 
ATOM   6111 O O   . PHE D 4 177 ? 131.216 165.353 92.482  1.00 95.93  ? 165 PHE S O   1 
ATOM   6112 C CB  . PHE D 4 177 ? 130.055 164.101 95.114  1.00 80.64  ? 165 PHE S CB  1 
ATOM   6113 C CG  . PHE D 4 177 ? 130.270 163.376 96.408  1.00 78.08  ? 165 PHE S CG  1 
ATOM   6114 C CD1 . PHE D 4 177 ? 131.397 163.613 97.169  1.00 80.51  ? 165 PHE S CD1 1 
ATOM   6115 C CD2 . PHE D 4 177 ? 129.350 162.451 96.857  1.00 82.72  ? 165 PHE S CD2 1 
ATOM   6116 C CE1 . PHE D 4 177 ? 131.598 162.949 98.355  1.00 85.42  ? 165 PHE S CE1 1 
ATOM   6117 C CE2 . PHE D 4 177 ? 129.548 161.781 98.042  1.00 85.11  ? 165 PHE S CE2 1 
ATOM   6118 C CZ  . PHE D 4 177 ? 130.673 162.032 98.792  1.00 85.73  ? 165 PHE S CZ  1 
ATOM   6119 N N   . LEU D 4 178 ? 129.651 163.861 91.844  1.00 67.14  ? 166 LEU S N   1 
ATOM   6120 C CA  . LEU D 4 178 ? 129.253 164.578 90.642  1.00 65.48  ? 166 LEU S CA  1 
ATOM   6121 C C   . LEU D 4 178 ? 127.834 165.081 90.836  1.00 70.42  ? 166 LEU S C   1 
ATOM   6122 O O   . LEU D 4 178 ? 126.927 164.293 91.120  1.00 82.30  ? 166 LEU S O   1 
ATOM   6123 C CB  . LEU D 4 178 ? 129.341 163.681 89.406  1.00 71.98  ? 166 LEU S CB  1 
ATOM   6124 C CG  . LEU D 4 178 ? 128.413 164.002 88.232  1.00 82.04  ? 166 LEU S CG  1 
ATOM   6125 C CD1 . LEU D 4 178 ? 128.719 165.362 87.626  1.00 81.05  ? 166 LEU S CD1 1 
ATOM   6126 C CD2 . LEU D 4 178 ? 128.501 162.914 87.175  1.00 79.47  ? 166 LEU S CD2 1 
ATOM   6127 N N   . GLN D 4 179 ? 127.646 166.385 90.685  1.00 77.08  ? 167 GLN S N   1 
ATOM   6128 C CA  . GLN D 4 179 ? 126.328 167.006 90.723  1.00 79.32  ? 167 GLN S CA  1 
ATOM   6129 C C   . GLN D 4 179 ? 126.067 167.565 89.332  1.00 81.44  ? 167 GLN S C   1 
ATOM   6130 O O   . GLN D 4 179 ? 126.551 168.648 88.988  1.00 86.14  ? 167 GLN S O   1 
ATOM   6131 C CB  . GLN D 4 179 ? 126.257 168.091 91.791  1.00 75.67  ? 167 GLN S CB  1 
ATOM   6132 C CG  . GLN D 4 179 ? 124.846 168.474 92.185  1.00 79.34  ? 167 GLN S CG  1 
ATOM   6133 C CD  . GLN D 4 179 ? 124.816 169.531 93.264  1.00 84.40  ? 167 GLN S CD  1 
ATOM   6134 O OE1 . GLN D 4 179 ? 125.840 170.128 93.592  1.00 82.59  ? 167 GLN S OE1 1 
ATOM   6135 N NE2 . GLN D 4 179 ? 123.637 169.769 93.826  1.00 87.33  ? 167 GLN S NE2 1 
ATOM   6136 N N   . ARG D 4 180 ? 125.356 166.805 88.519  1.00 80.72  ? 168 ARG S N   1 
ATOM   6137 C CA  . ARG D 4 180 ? 124.889 167.368 87.269  1.00 79.13  ? 168 ARG S CA  1 
ATOM   6138 C C   . ARG D 4 180 ? 123.708 168.295 87.544  1.00 76.58  ? 168 ARG S C   1 
ATOM   6139 O O   . ARG D 4 180 ? 122.971 168.094 88.513  1.00 77.25  ? 168 ARG S O   1 
ATOM   6140 C CB  . ARG D 4 180 ? 124.492 166.261 86.298  1.00 84.38  ? 168 ARG S CB  1 
ATOM   6141 C CG  . ARG D 4 180 ? 123.279 165.459 86.710  1.00 83.22  ? 168 ARG S CG  1 
ATOM   6142 C CD  . ARG D 4 180 ? 123.163 164.186 85.889  1.00 84.36  ? 168 ARG S CD  1 
ATOM   6143 N NE  . ARG D 4 180 ? 123.619 163.015 86.626  1.00 85.53  ? 168 ARG S NE  1 
ATOM   6144 C CZ  . ARG D 4 180 ? 124.645 162.256 86.267  1.00 87.00  ? 168 ARG S CZ  1 
ATOM   6145 N NH1 . ARG D 4 180 ? 125.353 162.520 85.183  1.00 90.91  ? 168 ARG S NH1 1 
ATOM   6146 N NH2 . ARG D 4 180 ? 124.967 161.205 87.015  1.00 82.92  ? 168 ARG S NH2 1 
ATOM   6147 N N   . PRO D 4 181 ? 123.529 169.331 86.728  1.00 77.42  ? 169 PRO S N   1 
ATOM   6148 C CA  . PRO D 4 181 ? 122.534 170.360 87.055  1.00 79.98  ? 169 PRO S CA  1 
ATOM   6149 C C   . PRO D 4 181 ? 121.140 169.777 87.220  1.00 83.44  ? 169 PRO S C   1 
ATOM   6150 O O   . PRO D 4 181 ? 120.719 168.896 86.469  1.00 87.57  ? 169 PRO S O   1 
ATOM   6151 C CB  . PRO D 4 181 ? 122.592 171.318 85.859  1.00 81.90  ? 169 PRO S CB  1 
ATOM   6152 C CG  . PRO D 4 181 ? 123.772 170.932 85.051  1.00 82.44  ? 169 PRO S CG  1 
ATOM   6153 C CD  . PRO D 4 181 ? 124.419 169.721 85.623  1.00 79.95  ? 169 PRO S CD  1 
ATOM   6154 N N   . GLY D 4 182 ? 120.425 170.282 88.224  1.00 81.86  ? 170 GLY S N   1 
ATOM   6155 C CA  . GLY D 4 182 ? 119.017 170.002 88.390  1.00 83.38  ? 170 GLY S CA  1 
ATOM   6156 C C   . GLY D 4 182 ? 118.654 169.043 89.503  1.00 82.14  ? 170 GLY S C   1 
ATOM   6157 O O   . GLY D 4 182 ? 117.496 169.053 89.939  1.00 86.10  ? 170 GLY S O   1 
ATOM   6158 N N   . GLN D 4 183 ? 119.583 168.222 89.983  1.00 85.88  ? 171 GLN S N   1 
ATOM   6159 C CA  . GLN D 4 183 ? 119.224 167.231 90.990  1.00 88.56  ? 171 GLN S CA  1 
ATOM   6160 C C   . GLN D 4 183 ? 120.443 166.892 91.842  1.00 85.13  ? 171 GLN S C   1 
ATOM   6161 O O   . GLN D 4 183 ? 121.516 167.483 91.701  1.00 86.54  ? 171 GLN S O   1 
ATOM   6162 C CB  . GLN D 4 183 ? 118.603 165.988 90.337  1.00 86.23  ? 171 GLN S CB  1 
ATOM   6163 C CG  . GLN D 4 183 ? 119.574 164.908 89.880  1.00 88.53  ? 171 GLN S CG  1 
ATOM   6164 C CD  . GLN D 4 183 ? 120.288 165.258 88.593  1.00 88.37  ? 171 GLN S CD  1 
ATOM   6165 O OE1 . GLN D 4 183 ? 120.678 166.403 88.370  1.00 89.60  ? 171 GLN S OE1 1 
ATOM   6166 N NE2 . GLN D 4 183 ? 120.451 164.266 87.726  1.00 82.88  ? 171 GLN S NE2 1 
ATOM   6167 N N   . SER D 4 184 ? 120.253 165.922 92.730  1.00 79.14  ? 172 SER S N   1 
ATOM   6168 C CA  . SER D 4 184 ? 121.193 165.661 93.808  1.00 76.72  ? 172 SER S CA  1 
ATOM   6169 C C   . SER D 4 184 ? 122.506 165.093 93.275  1.00 74.97  ? 172 SER S C   1 
ATOM   6170 O O   . SER D 4 184 ? 122.534 164.502 92.190  1.00 80.07  ? 172 SER S O   1 
ATOM   6171 C CB  . SER D 4 184 ? 120.570 164.684 94.802  1.00 84.04  ? 172 SER S CB  1 
ATOM   6172 O OG  . SER D 4 184 ? 120.334 163.430 94.197  1.00 85.44  ? 172 SER S OG  1 
ATOM   6173 N N   . PRO D 4 185 ? 123.606 165.252 94.008  1.00 66.23  ? 173 PRO S N   1 
ATOM   6174 C CA  . PRO D 4 185 ? 124.871 164.642 93.589  1.00 72.12  ? 173 PRO S CA  1 
ATOM   6175 C C   . PRO D 4 185 ? 124.870 163.137 93.808  1.00 69.54  ? 173 PRO S C   1 
ATOM   6176 O O   . PRO D 4 185 ? 124.050 162.582 94.541  1.00 76.42  ? 173 PRO S O   1 
ATOM   6177 C CB  . PRO D 4 185 ? 125.920 165.323 94.478  1.00 75.57  ? 173 PRO S CB  1 
ATOM   6178 C CG  . PRO D 4 185 ? 125.200 166.393 95.233  1.00 77.49  ? 173 PRO S CG  1 
ATOM   6179 C CD  . PRO D 4 185 ? 123.756 166.046 95.236  1.00 73.40  ? 173 PRO S CD  1 
ATOM   6180 N N   . GLN D 4 186 ? 125.820 162.478 93.151  1.00 74.52  ? 174 GLN S N   1 
ATOM   6181 C CA  . GLN D 4 186 ? 125.991 161.038 93.246  1.00 71.10  ? 174 GLN S CA  1 
ATOM   6182 C C   . GLN D 4 186 ? 127.468 160.714 93.413  1.00 77.44  ? 174 GLN S C   1 
ATOM   6183 O O   . GLN D 4 186 ? 128.338 161.505 93.045  1.00 87.52  ? 174 GLN S O   1 
ATOM   6184 C CB  . GLN D 4 186 ? 125.427 160.325 92.012  1.00 75.34  ? 174 GLN S CB  1 
ATOM   6185 C CG  . GLN D 4 186 ? 126.426 160.138 90.884  1.00 83.55  ? 174 GLN S CG  1 
ATOM   6186 C CD  . GLN D 4 186 ? 125.828 159.425 89.688  1.00 90.37  ? 174 GLN S CD  1 
ATOM   6187 O OE1 . GLN D 4 186 ? 124.627 159.155 89.647  1.00 91.90  ? 174 GLN S OE1 1 
ATOM   6188 N NE2 . GLN D 4 186 ? 126.665 159.113 88.706  1.00 86.03  ? 174 GLN S NE2 1 
ATOM   6189 N N   . LEU D 4 187 ? 127.742 159.542 93.977  1.00 63.46  ? 175 LEU S N   1 
ATOM   6190 C CA  . LEU D 4 187 ? 129.110 159.146 94.280  1.00 58.56  ? 175 LEU S CA  1 
ATOM   6191 C C   . LEU D 4 187 ? 129.794 158.581 93.042  1.00 64.52  ? 175 LEU S C   1 
ATOM   6192 O O   . LEU D 4 187 ? 129.249 157.702 92.368  1.00 74.87  ? 175 LEU S O   1 
ATOM   6193 C CB  . LEU D 4 187 ? 129.124 158.114 95.404  1.00 64.97  ? 175 LEU S CB  1 
ATOM   6194 C CG  . LEU D 4 187 ? 130.494 157.563 95.790  1.00 73.63  ? 175 LEU S CG  1 
ATOM   6195 C CD1 . LEU D 4 187 ? 131.364 158.661 96.368  1.00 75.29  ? 175 LEU S CD1 1 
ATOM   6196 C CD2 . LEU D 4 187 ? 130.344 156.426 96.782  1.00 80.66  ? 175 LEU S CD2 1 
ATOM   6197 N N   . LEU D 4 188 ? 130.989 159.091 92.743  1.00 75.59  ? 176 LEU S N   1 
ATOM   6198 C CA  . LEU D 4 188 ? 131.808 158.574 91.650  1.00 79.51  ? 176 LEU S CA  1 
ATOM   6199 C C   . LEU D 4 188 ? 132.919 157.662 92.156  1.00 77.97  ? 176 LEU S C   1 
ATOM   6200 O O   . LEU D 4 188 ? 133.018 156.504 91.743  1.00 85.48  ? 176 LEU S O   1 
ATOM   6201 C CB  . LEU D 4 188 ? 132.415 159.727 90.842  1.00 77.62  ? 176 LEU S CB  1 
ATOM   6202 C CG  . LEU D 4 188 ? 131.483 160.759 90.218  1.00 82.71  ? 176 LEU S CG  1 
ATOM   6203 C CD1 . LEU D 4 188 ? 132.279 161.668 89.300  1.00 81.53  ? 176 LEU S CD1 1 
ATOM   6204 C CD2 . LEU D 4 188 ? 130.359 160.082 89.461  1.00 82.47  ? 176 LEU S CD2 1 
ATOM   6205 N N   . ILE D 4 189 ? 133.766 158.174 93.042  1.00 65.28  ? 177 ILE S N   1 
ATOM   6206 C CA  . ILE D 4 189 ? 134.909 157.444 93.573  1.00 61.64  ? 177 ILE S CA  1 
ATOM   6207 C C   . ILE D 4 189 ? 134.842 157.504 95.089  1.00 70.83  ? 177 ILE S C   1 
ATOM   6208 O O   . ILE D 4 189 ? 134.597 158.572 95.658  1.00 79.33  ? 177 ILE S O   1 
ATOM   6209 C CB  . ILE D 4 189 ? 136.242 158.035 93.078  1.00 68.54  ? 177 ILE S CB  1 
ATOM   6210 C CG1 . ILE D 4 189 ? 136.289 158.058 91.553  1.00 78.87  ? 177 ILE S CG1 1 
ATOM   6211 C CG2 . ILE D 4 189 ? 137.410 157.242 93.627  1.00 65.15  ? 177 ILE S CG2 1 
ATOM   6212 C CD1 . ILE D 4 189 ? 136.150 156.699 90.925  1.00 80.23  ? 177 ILE S CD1 1 
ATOM   6213 N N   . TYR D 4 190 ? 135.050 156.368 95.743  1.00 74.19  ? 178 TYR S N   1 
ATOM   6214 C CA  . TYR D 4 190 ? 135.181 156.327 97.191  1.00 75.99  ? 178 TYR S CA  1 
ATOM   6215 C C   . TYR D 4 190 ? 136.550 155.769 97.541  1.00 78.58  ? 178 TYR S C   1 
ATOM   6216 O O   . TYR D 4 190 ? 137.062 154.885 96.848  1.00 83.78  ? 178 TYR S O   1 
ATOM   6217 C CB  . TYR D 4 190 ? 134.066 155.496 97.839  1.00 75.25  ? 178 TYR S CB  1 
ATOM   6218 C CG  . TYR D 4 190 ? 134.064 154.028 97.489  1.00 75.86  ? 178 TYR S CG  1 
ATOM   6219 C CD1 . TYR D 4 190 ? 134.826 153.121 98.211  1.00 78.41  ? 178 TYR S CD1 1 
ATOM   6220 C CD2 . TYR D 4 190 ? 133.291 153.546 96.445  1.00 73.74  ? 178 TYR S CD2 1 
ATOM   6221 C CE1 . TYR D 4 190 ? 134.821 151.781 97.900  1.00 73.34  ? 178 TYR S CE1 1 
ATOM   6222 C CE2 . TYR D 4 190 ? 133.283 152.206 96.126  1.00 75.34  ? 178 TYR S CE2 1 
ATOM   6223 C CZ  . TYR D 4 190 ? 134.051 151.329 96.855  1.00 74.47  ? 178 TYR S CZ  1 
ATOM   6224 O OH  . TYR D 4 190 ? 134.045 149.992 96.540  1.00 81.11  ? 178 TYR S OH  1 
ATOM   6225 N N   . ARG D 4 191 ? 137.146 156.306 98.606  1.00 70.11  ? 179 ARG S N   1 
ATOM   6226 C CA  . ARG D 4 191 ? 138.502 155.948 99.022  1.00 66.71  ? 179 ARG S CA  1 
ATOM   6227 C C   . ARG D 4 191 ? 139.529 156.268 97.939  1.00 75.96  ? 179 ARG S C   1 
ATOM   6228 O O   . ARG D 4 191 ? 140.516 155.549 97.784  1.00 82.22  ? 179 ARG S O   1 
ATOM   6229 C CB  . ARG D 4 191 ? 138.597 154.475 99.426  1.00 72.25  ? 179 ARG S CB  1 
ATOM   6230 C CG  . ARG D 4 191 ? 139.208 154.245 100.791 1.00 76.06  ? 179 ARG S CG  1 
ATOM   6231 C CD  . ARG D 4 191 ? 138.211 154.523 101.898 1.00 74.66  ? 179 ARG S CD  1 
ATOM   6232 N NE  . ARG D 4 191 ? 136.958 153.799 101.719 1.00 73.44  ? 179 ARG S NE  1 
ATOM   6233 C CZ  . ARG D 4 191 ? 136.823 152.484 101.825 1.00 74.84  ? 179 ARG S CZ  1 
ATOM   6234 N NH1 . ARG D 4 191 ? 137.849 151.704 102.121 1.00 79.34  ? 179 ARG S NH1 1 
ATOM   6235 N NH2 . ARG D 4 191 ? 135.627 151.938 101.635 1.00 72.43  ? 179 ARG S NH2 1 
ATOM   6236 N N   . MET D 4 192 ? 139.247 157.303 97.144  1.00 85.21  ? 180 MET S N   1 
ATOM   6237 C CA  . MET D 4 192 ? 140.151 157.971 96.206  1.00 83.11  ? 180 MET S CA  1 
ATOM   6238 C C   . MET D 4 192 ? 140.577 157.113 95.022  1.00 88.53  ? 180 MET S C   1 
ATOM   6239 O O   . MET D 4 192 ? 141.172 157.630 94.071  1.00 90.93  ? 180 MET S O   1 
ATOM   6240 C CB  . MET D 4 192 ? 141.425 158.461 96.904  1.00 82.71  ? 180 MET S CB  1 
ATOM   6241 C CG  . MET D 4 192 ? 142.556 157.438 96.923  1.00 83.17  ? 180 MET S CG  1 
ATOM   6242 S SD  . MET D 4 192 ? 143.816 157.679 95.659  1.00 98.56  ? 180 MET S SD  1 
ATOM   6243 C CE  . MET D 4 192 ? 144.900 158.820 96.491  1.00 85.85  ? 180 MET S CE  1 
ATOM   6244 N N   . SER D 4 193 ? 140.283 155.817 95.047  1.00 85.52  ? 181 SER S N   1 
ATOM   6245 C CA  . SER D 4 193 ? 140.701 154.957 93.951  1.00 76.86  ? 181 SER S CA  1 
ATOM   6246 C C   . SER D 4 193 ? 139.721 153.843 93.626  1.00 74.79  ? 181 SER S C   1 
ATOM   6247 O O   . SER D 4 193 ? 140.009 153.045 92.729  1.00 81.08  ? 181 SER S O   1 
ATOM   6248 C CB  . SER D 4 193 ? 142.078 154.346 94.250  1.00 74.75  ? 181 SER S CB  1 
ATOM   6249 O OG  . SER D 4 193 ? 142.022 153.488 95.375  1.00 73.99  ? 181 SER S OG  1 
ATOM   6250 N N   . ASN D 4 194 ? 138.587 153.755 94.308  1.00 68.21  ? 182 ASN S N   1 
ATOM   6251 C CA  . ASN D 4 194 ? 137.640 152.668 94.109  1.00 64.98  ? 182 ASN S CA  1 
ATOM   6252 C C   . ASN D 4 194 ? 136.436 153.187 93.343  1.00 72.48  ? 182 ASN S C   1 
ATOM   6253 O O   . ASN D 4 194 ? 135.838 154.198 93.726  1.00 76.24  ? 182 ASN S O   1 
ATOM   6254 C CB  . ASN D 4 194 ? 137.191 152.050 95.437  1.00 71.17  ? 182 ASN S CB  1 
ATOM   6255 C CG  . ASN D 4 194 ? 138.340 151.475 96.256  1.00 82.40  ? 182 ASN S CG  1 
ATOM   6256 O OD1 . ASN D 4 194 ? 139.505 151.701 95.933  1.00 86.42  ? 182 ASN S OD1 1 
ATOM   6257 N ND2 . ASN D 4 194 ? 138.025 150.759 97.325  1.00 80.00  ? 182 ASN S ND2 1 
ATOM   6258 N N   . LEU D 4 195 ? 136.090 152.498 92.264  1.00 83.53  ? 183 LEU S N   1 
ATOM   6259 C CA  . LEU D 4 195 ? 134.947 152.891 91.460  1.00 74.32  ? 183 LEU S CA  1 
ATOM   6260 C C   . LEU D 4 195 ? 133.657 152.628 92.228  1.00 75.74  ? 183 LEU S C   1 
ATOM   6261 O O   . LEU D 4 195 ? 133.544 151.659 92.982  1.00 78.48  ? 183 LEU S O   1 
ATOM   6262 C CB  . LEU D 4 195 ? 134.940 152.119 90.142  1.00 73.94  ? 183 LEU S CB  1 
ATOM   6263 C CG  . LEU D 4 195 ? 134.197 152.754 88.971  1.00 78.88  ? 183 LEU S CG  1 
ATOM   6264 C CD1 . LEU D 4 195 ? 134.254 154.262 89.090  1.00 79.19  ? 183 LEU S CD1 1 
ATOM   6265 C CD2 . LEU D 4 195 ? 134.780 152.290 87.647  1.00 82.07  ? 183 LEU S CD2 1 
ATOM   6266 N N   . ALA D 4 196 ? 132.676 153.503 92.034  1.00 78.75  ? 184 ALA S N   1 
ATOM   6267 C CA  . ALA D 4 196 ? 131.401 153.338 92.711  1.00 78.44  ? 184 ALA S CA  1 
ATOM   6268 C C   . ALA D 4 196 ? 130.571 152.265 92.012  1.00 86.19  ? 184 ALA S C   1 
ATOM   6269 O O   . ALA D 4 196 ? 131.006 151.630 91.048  1.00 92.95  ? 184 ALA S O   1 
ATOM   6270 C CB  . ALA D 4 196 ? 130.647 154.664 92.764  1.00 80.59  ? 184 ALA S CB  1 
ATOM   6271 N N   . SER D 4 197 ? 129.357 152.056 92.507  1.00 80.79  ? 185 SER S N   1 
ATOM   6272 C CA  . SER D 4 197 ? 128.437 151.086 91.932  1.00 78.53  ? 185 SER S CA  1 
ATOM   6273 C C   . SER D 4 197 ? 127.443 151.807 91.034  1.00 80.15  ? 185 SER S C   1 
ATOM   6274 O O   . SER D 4 197 ? 126.870 152.827 91.428  1.00 85.11  ? 185 SER S O   1 
ATOM   6275 C CB  . SER D 4 197 ? 127.701 150.315 93.027  1.00 80.57  ? 185 SER S CB  1 
ATOM   6276 O OG  . SER D 4 197 ? 126.955 151.194 93.850  1.00 88.69  ? 185 SER S OG  1 
ATOM   6277 N N   . GLY D 4 198 ? 127.244 151.277 89.831  1.00 76.05  ? 186 GLY S N   1 
ATOM   6278 C CA  . GLY D 4 198 ? 126.322 151.878 88.893  1.00 77.38  ? 186 GLY S CA  1 
ATOM   6279 C C   . GLY D 4 198 ? 126.869 153.051 88.116  1.00 81.45  ? 186 GLY S C   1 
ATOM   6280 O O   . GLY D 4 198 ? 126.105 153.709 87.402  1.00 88.24  ? 186 GLY S O   1 
ATOM   6281 N N   . VAL D 4 199 ? 128.162 153.336 88.229  1.00 78.21  ? 187 VAL S N   1 
ATOM   6282 C CA  . VAL D 4 199 ? 128.768 154.462 87.524  1.00 81.95  ? 187 VAL S CA  1 
ATOM   6283 C C   . VAL D 4 199 ? 129.717 153.899 86.469  1.00 80.34  ? 187 VAL S C   1 
ATOM   6284 O O   . VAL D 4 199 ? 130.294 152.821 86.672  1.00 82.12  ? 187 VAL S O   1 
ATOM   6285 C CB  . VAL D 4 199 ? 129.471 155.409 88.513  1.00 82.65  ? 187 VAL S CB  1 
ATOM   6286 C CG1 . VAL D 4 199 ? 130.204 156.510 87.787  1.00 80.75  ? 187 VAL S CG1 1 
ATOM   6287 C CG2 . VAL D 4 199 ? 128.489 155.978 89.528  1.00 83.29  ? 187 VAL S CG2 1 
ATOM   6288 N N   . PRO D 4 200 ? 129.877 154.560 85.323  1.00 81.66  ? 188 PRO S N   1 
ATOM   6289 C CA  . PRO D 4 200 ? 130.687 153.989 84.239  1.00 82.30  ? 188 PRO S CA  1 
ATOM   6290 C C   . PRO D 4 200 ? 132.144 153.793 84.631  1.00 83.39  ? 188 PRO S C   1 
ATOM   6291 O O   . PRO D 4 200 ? 132.634 154.286 85.647  1.00 89.38  ? 188 PRO S O   1 
ATOM   6292 C CB  . PRO D 4 200 ? 130.560 155.013 83.104  1.00 85.84  ? 188 PRO S CB  1 
ATOM   6293 C CG  . PRO D 4 200 ? 129.713 156.127 83.628  1.00 87.99  ? 188 PRO S CG  1 
ATOM   6294 C CD  . PRO D 4 200 ? 129.010 155.645 84.843  1.00 84.39  ? 188 PRO S CD  1 
ATOM   6295 N N   . ASP D 4 201 ? 132.842 153.042 83.777  1.00 86.56  ? 189 ASP S N   1 
ATOM   6296 C CA  . ASP D 4 201 ? 134.241 152.700 84.000  1.00 91.53  ? 189 ASP S CA  1 
ATOM   6297 C C   . ASP D 4 201 ? 135.160 153.877 83.691  1.00 94.66  ? 189 ASP S C   1 
ATOM   6298 O O   . ASP D 4 201 ? 136.209 154.018 84.329  1.00 96.71  ? 189 ASP S O   1 
ATOM   6299 C CB  . ASP D 4 201 ? 134.578 151.458 83.156  1.00 95.21  ? 189 ASP S CB  1 
ATOM   6300 C CG  . ASP D 4 201 ? 136.045 151.016 83.243  1.00 99.60  ? 189 ASP S CG  1 
ATOM   6301 O OD1 . ASP D 4 201 ? 136.980 151.841 83.242  1.00 99.75  ? 189 ASP S OD1 1 
ATOM   6302 O OD2 . ASP D 4 201 ? 136.262 149.789 83.314  1.00 97.74  ? 189 ASP S OD2 1 
ATOM   6303 N N   . ARG D 4 202 ? 134.765 154.748 82.757  1.00 93.81  ? 190 ARG S N   1 
ATOM   6304 C CA  . ARG D 4 202 ? 135.647 155.821 82.300  1.00 97.16  ? 190 ARG S CA  1 
ATOM   6305 C C   . ARG D 4 202 ? 136.145 156.681 83.455  1.00 100.80 ? 190 ARG S C   1 
ATOM   6306 O O   . ARG D 4 202 ? 137.291 157.144 83.444  1.00 102.19 ? 190 ARG S O   1 
ATOM   6307 C CB  . ARG D 4 202 ? 134.925 156.688 81.269  1.00 100.18 ? 190 ARG S CB  1 
ATOM   6308 C CG  . ARG D 4 202 ? 133.442 156.865 81.535  1.00 98.75  ? 190 ARG S CG  1 
ATOM   6309 C CD  . ARG D 4 202 ? 132.668 157.021 80.238  1.00 97.47  ? 190 ARG S CD  1 
ATOM   6310 N NE  . ARG D 4 202 ? 131.228 157.052 80.460  1.00 98.05  ? 190 ARG S NE  1 
ATOM   6311 C CZ  . ARG D 4 202 ? 130.548 158.136 80.802  1.00 98.61  ? 190 ARG S CZ  1 
ATOM   6312 N NH1 . ARG D 4 202 ? 131.147 159.302 80.972  1.00 98.32  ? 190 ARG S NH1 1 
ATOM   6313 N NH2 . ARG D 4 202 ? 129.232 158.050 80.977  1.00 97.77  ? 190 ARG S NH2 1 
ATOM   6314 N N   . PHE D 4 203 ? 135.299 156.909 84.456  1.00 90.10  ? 191 PHE S N   1 
ATOM   6315 C CA  . PHE D 4 203 ? 135.713 157.667 85.627  1.00 83.18  ? 191 PHE S CA  1 
ATOM   6316 C C   . PHE D 4 203 ? 136.794 156.912 86.389  1.00 85.58  ? 191 PHE S C   1 
ATOM   6317 O O   . PHE D 4 203 ? 136.707 155.696 86.575  1.00 89.08  ? 191 PHE S O   1 
ATOM   6318 C CB  . PHE D 4 203 ? 134.513 157.918 86.537  1.00 82.33  ? 191 PHE S CB  1 
ATOM   6319 C CG  . PHE D 4 203 ? 133.650 159.059 86.100  1.00 85.54  ? 191 PHE S CG  1 
ATOM   6320 C CD1 . PHE D 4 203 ? 134.107 160.360 86.174  1.00 93.35  ? 191 PHE S CD1 1 
ATOM   6321 C CD2 . PHE D 4 203 ? 132.379 158.829 85.613  1.00 87.51  ? 191 PHE S CD2 1 
ATOM   6322 C CE1 . PHE D 4 203 ? 133.309 161.409 85.773  1.00 94.97  ? 191 PHE S CE1 1 
ATOM   6323 C CE2 . PHE D 4 203 ? 131.577 159.873 85.210  1.00 92.61  ? 191 PHE S CE2 1 
ATOM   6324 C CZ  . PHE D 4 203 ? 132.043 161.164 85.288  1.00 93.88  ? 191 PHE S CZ  1 
ATOM   6325 N N   . SER D 4 204 ? 137.818 157.635 86.835  1.00 85.15  ? 192 SER S N   1 
ATOM   6326 C CA  . SER D 4 204 ? 138.874 157.013 87.620  1.00 84.50  ? 192 SER S CA  1 
ATOM   6327 C C   . SER D 4 204 ? 139.477 158.048 88.556  1.00 90.41  ? 192 SER S C   1 
ATOM   6328 O O   . SER D 4 204 ? 139.339 159.253 88.347  1.00 90.75  ? 192 SER S O   1 
ATOM   6329 C CB  . SER D 4 204 ? 139.957 156.407 86.722  1.00 84.06  ? 192 SER S CB  1 
ATOM   6330 O OG  . SER D 4 204 ? 141.093 156.033 87.481  1.00 90.67  ? 192 SER S OG  1 
ATOM   6331 N N   . GLY D 4 205 ? 140.154 157.563 89.588  1.00 94.09  ? 193 GLY S N   1 
ATOM   6332 C CA  . GLY D 4 205 ? 140.815 158.433 90.539  1.00 93.00  ? 193 GLY S CA  1 
ATOM   6333 C C   . GLY D 4 205 ? 142.216 157.945 90.837  1.00 90.38  ? 193 GLY S C   1 
ATOM   6334 O O   . GLY D 4 205 ? 142.496 156.747 90.818  1.00 90.85  ? 193 GLY S O   1 
ATOM   6335 N N   . SER D 4 206 ? 143.102 158.897 91.114  1.00 87.30  ? 194 SER S N   1 
ATOM   6336 C CA  . SER D 4 206 ? 144.506 158.579 91.332  1.00 87.08  ? 194 SER S CA  1 
ATOM   6337 C C   . SER D 4 206 ? 145.150 159.703 92.135  1.00 89.54  ? 194 SER S C   1 
ATOM   6338 O O   . SER D 4 206 ? 144.517 160.712 92.456  1.00 94.13  ? 194 SER S O   1 
ATOM   6339 C CB  . SER D 4 206 ? 145.230 158.356 90.002  1.00 92.54  ? 194 SER S CB  1 
ATOM   6340 O OG  . SER D 4 206 ? 144.720 159.215 88.999  1.00 93.12  ? 194 SER S OG  1 
ATOM   6341 N N   . GLY D 4 207 ? 146.426 159.523 92.440  1.00 90.51  ? 195 GLY S N   1 
ATOM   6342 C CA  . GLY D 4 207 ? 147.188 160.464 93.232  1.00 89.99  ? 195 GLY S CA  1 
ATOM   6343 C C   . GLY D 4 207 ? 147.722 159.824 94.497  1.00 93.17  ? 195 GLY S C   1 
ATOM   6344 O O   . GLY D 4 207 ? 147.484 158.653 94.788  1.00 93.67  ? 195 GLY S O   1 
ATOM   6345 N N   . SER D 4 208 ? 148.493 160.618 95.233  1.00 96.45  ? 196 SER S N   1 
ATOM   6346 C CA  . SER D 4 208 ? 148.977 160.217 96.546  1.00 96.40  ? 196 SER S CA  1 
ATOM   6347 C C   . SER D 4 208 ? 149.398 161.469 97.298  1.00 95.88  ? 196 SER S C   1 
ATOM   6348 O O   . SER D 4 208 ? 149.645 162.521 96.704  1.00 95.08  ? 196 SER S O   1 
ATOM   6349 C CB  . SER D 4 208 ? 150.138 159.223 96.442  1.00 100.58 ? 196 SER S CB  1 
ATOM   6350 O OG  . SER D 4 208 ? 151.384 159.875 96.606  1.00 102.50 ? 196 SER S OG  1 
ATOM   6351 N N   . GLY D 4 209 ? 149.479 161.342 98.618  1.00 97.01  ? 197 GLY S N   1 
ATOM   6352 C CA  . GLY D 4 209 ? 149.929 162.449 99.436  1.00 102.16 ? 197 GLY S CA  1 
ATOM   6353 C C   . GLY D 4 209 ? 148.870 163.505 99.674  1.00 102.81 ? 197 GLY S C   1 
ATOM   6354 O O   . GLY D 4 209 ? 147.927 163.285 100.440 1.00 101.41 ? 197 GLY S O   1 
ATOM   6355 N N   . THR D 4 210 ? 149.018 164.658 99.026  1.00 103.34 ? 198 THR S N   1 
ATOM   6356 C CA  . THR D 4 210 ? 148.149 165.804 99.252  1.00 99.35  ? 198 THR S CA  1 
ATOM   6357 C C   . THR D 4 210 ? 147.474 166.334 97.995  1.00 100.72 ? 198 THR S C   1 
ATOM   6358 O O   . THR D 4 210 ? 146.437 166.991 98.107  1.00 100.70 ? 198 THR S O   1 
ATOM   6359 C CB  . THR D 4 210 ? 148.935 166.950 99.906  1.00 103.75 ? 198 THR S CB  1 
ATOM   6360 O OG1 . THR D 4 210 ? 150.250 167.014 99.341  1.00 108.40 ? 198 THR S OG1 1 
ATOM   6361 C CG2 . THR D 4 210 ? 149.041 166.733 101.408 1.00 103.34 ? 198 THR S CG2 1 
ATOM   6362 N N   . ALA D 4 211 ? 148.042 166.100 96.815  1.00 101.38 ? 199 ALA S N   1 
ATOM   6363 C CA  . ALA D 4 211 ? 147.429 166.484 95.547  1.00 102.63 ? 199 ALA S CA  1 
ATOM   6364 C C   . ALA D 4 211 ? 146.882 165.227 94.881  1.00 103.62 ? 199 ALA S C   1 
ATOM   6365 O O   . ALA D 4 211 ? 147.622 164.265 94.657  1.00 105.27 ? 199 ALA S O   1 
ATOM   6366 C CB  . ALA D 4 211 ? 148.435 167.192 94.644  1.00 104.12 ? 199 ALA S CB  1 
ATOM   6367 N N   . PHE D 4 212 ? 145.588 165.229 94.569  1.00 104.87 ? 200 PHE S N   1 
ATOM   6368 C CA  . PHE D 4 212 ? 144.929 164.073 93.987  1.00 101.84 ? 200 PHE S CA  1 
ATOM   6369 C C   . PHE D 4 212 ? 144.217 164.487 92.706  1.00 103.12 ? 200 PHE S C   1 
ATOM   6370 O O   . PHE D 4 212 ? 143.923 165.666 92.493  1.00 106.57 ? 200 PHE S O   1 
ATOM   6371 C CB  . PHE D 4 212 ? 143.909 163.445 94.941  1.00 96.68  ? 200 PHE S CB  1 
ATOM   6372 C CG  . PHE D 4 212 ? 144.355 163.370 96.381  1.00 98.01  ? 200 PHE S CG  1 
ATOM   6373 C CD1 . PHE D 4 212 ? 144.501 164.513 97.153  1.00 101.48 ? 200 PHE S CD1 1 
ATOM   6374 C CD2 . PHE D 4 212 ? 144.626 162.150 96.961  1.00 103.86 ? 200 PHE S CD2 1 
ATOM   6375 C CE1 . PHE D 4 212 ? 144.898 164.432 98.469  1.00 104.23 ? 200 PHE S CE1 1 
ATOM   6376 C CE2 . PHE D 4 212 ? 145.032 162.067 98.271  1.00 105.66 ? 200 PHE S CE2 1 
ATOM   6377 C CZ  . PHE D 4 212 ? 145.167 163.208 99.027  1.00 105.66 ? 200 PHE S CZ  1 
ATOM   6378 N N   . THR D 4 213 ? 143.925 163.507 91.850  1.00 97.36  ? 201 THR S N   1 
ATOM   6379 C CA  . THR D 4 213 ? 143.287 163.793 90.574  1.00 96.64  ? 201 THR S CA  1 
ATOM   6380 C C   . THR D 4 213 ? 142.173 162.795 90.298  1.00 96.51  ? 201 THR S C   1 
ATOM   6381 O O   . THR D 4 213 ? 142.209 161.649 90.753  1.00 99.99  ? 201 THR S O   1 
ATOM   6382 C CB  . THR D 4 213 ? 144.291 163.761 89.415  1.00 95.42  ? 201 THR S CB  1 
ATOM   6383 O OG1 . THR D 4 213 ? 145.139 162.614 89.548  1.00 99.48  ? 201 THR S OG1 1 
ATOM   6384 C CG2 . THR D 4 213 ? 145.143 165.019 89.411  1.00 95.62  ? 201 THR S CG2 1 
ATOM   6385 N N   . LEU D 4 214 ? 141.177 163.258 89.547  1.00 102.66 ? 202 LEU S N   1 
ATOM   6386 C CA  . LEU D 4 214 ? 140.121 162.420 88.998  1.00 104.07 ? 202 LEU S CA  1 
ATOM   6387 C C   . LEU D 4 214 ? 140.129 162.581 87.486  1.00 107.87 ? 202 LEU S C   1 
ATOM   6388 O O   . LEU D 4 214 ? 140.028 163.701 86.978  1.00 112.92 ? 202 LEU S O   1 
ATOM   6389 C CB  . LEU D 4 214 ? 138.752 162.796 89.573  1.00 103.36 ? 202 LEU S CB  1 
ATOM   6390 C CG  . LEU D 4 214 ? 137.508 162.240 88.874  1.00 103.25 ? 202 LEU S CG  1 
ATOM   6391 C CD1 . LEU D 4 214 ? 136.497 161.768 89.900  1.00 106.20 ? 202 LEU S CD1 1 
ATOM   6392 C CD2 . LEU D 4 214 ? 136.880 163.290 87.972  1.00 104.67 ? 202 LEU S CD2 1 
ATOM   6393 N N   . THR D 4 215 ? 140.245 161.467 86.775  1.00 101.69 ? 203 THR S N   1 
ATOM   6394 C CA  . THR D 4 215 ? 140.390 161.467 85.327  1.00 96.58  ? 203 THR S CA  1 
ATOM   6395 C C   . THR D 4 215 ? 139.142 160.891 84.677  1.00 94.56  ? 203 THR S C   1 
ATOM   6396 O O   . THR D 4 215 ? 138.658 159.825 85.078  1.00 100.53 ? 203 THR S O   1 
ATOM   6397 C CB  . THR D 4 215 ? 141.619 160.663 84.899  1.00 97.60  ? 203 THR S CB  1 
ATOM   6398 O OG1 . THR D 4 215 ? 141.517 159.329 85.410  1.00 99.89  ? 203 THR S OG1 1 
ATOM   6399 C CG2 . THR D 4 215 ? 142.888 161.307 85.431  1.00 98.44  ? 203 THR S CG2 1 
ATOM   6400 N N   . ILE D 4 216 ? 138.624 161.599 83.680  1.00 96.85  ? 204 ILE S N   1 
ATOM   6401 C CA  . ILE D 4 216 ? 137.541 161.110 82.837  1.00 101.00 ? 204 ILE S CA  1 
ATOM   6402 C C   . ILE D 4 216 ? 138.137 160.852 81.461  1.00 103.99 ? 204 ILE S C   1 
ATOM   6403 O O   . ILE D 4 216 ? 138.566 161.789 80.774  1.00 105.63 ? 204 ILE S O   1 
ATOM   6404 C CB  . ILE D 4 216 ? 136.376 162.103 82.765  1.00 98.80  ? 204 ILE S CB  1 
ATOM   6405 C CG1 . ILE D 4 216 ? 136.195 162.803 84.108  1.00 96.45  ? 204 ILE S CG1 1 
ATOM   6406 C CG2 . ILE D 4 216 ? 135.096 161.390 82.372  1.00 99.33  ? 204 ILE S CG2 1 
ATOM   6407 C CD1 . ILE D 4 216 ? 135.135 163.867 84.087  1.00 99.10  ? 204 ILE S CD1 1 
ATOM   6408 N N   . SER D 4 217 ? 138.179 159.578 81.065  1.00 99.28  ? 205 SER S N   1 
ATOM   6409 C CA  . SER D 4 217 ? 138.787 159.217 79.789  1.00 99.50  ? 205 SER S CA  1 
ATOM   6410 C C   . SER D 4 217 ? 137.978 159.756 78.616  1.00 102.49 ? 205 SER S C   1 
ATOM   6411 O O   . SER D 4 217 ? 138.548 160.250 77.637  1.00 103.90 ? 205 SER S O   1 
ATOM   6412 C CB  . SER D 4 217 ? 138.936 157.700 79.691  1.00 100.35 ? 205 SER S CB  1 
ATOM   6413 O OG  . SER D 4 217 ? 139.481 157.324 78.440  1.00 106.46 ? 205 SER S OG  1 
ATOM   6414 N N   . ARG D 4 218 ? 136.654 159.667 78.694  1.00 107.00 ? 206 ARG S N   1 
ATOM   6415 C CA  . ARG D 4 218 ? 135.770 160.188 77.662  1.00 106.84 ? 206 ARG S CA  1 
ATOM   6416 C C   . ARG D 4 218 ? 134.654 160.989 78.311  1.00 108.48 ? 206 ARG S C   1 
ATOM   6417 O O   . ARG D 4 218 ? 134.088 160.573 79.325  1.00 111.84 ? 206 ARG S O   1 
ATOM   6418 C CB  . ARG D 4 218 ? 135.176 159.064 76.807  1.00 106.58 ? 206 ARG S CB  1 
ATOM   6419 C CG  . ARG D 4 218 ? 135.918 158.820 75.505  1.00 110.09 ? 206 ARG S CG  1 
ATOM   6420 C CD  . ARG D 4 218 ? 135.757 157.379 75.034  1.00 109.77 ? 206 ARG S CD  1 
ATOM   6421 N NE  . ARG D 4 218 ? 136.475 156.416 75.864  1.00 110.24 ? 206 ARG S NE  1 
ATOM   6422 C CZ  . ARG D 4 218 ? 137.786 156.413 76.072  1.00 111.65 ? 206 ARG S CZ  1 
ATOM   6423 N NH1 . ARG D 4 218 ? 138.588 157.282 75.479  1.00 111.69 ? 206 ARG S NH1 1 
ATOM   6424 N NH2 . ARG D 4 218 ? 138.309 155.501 76.887  1.00 110.40 ? 206 ARG S NH2 1 
ATOM   6425 N N   . LEU D 4 219 ? 134.342 162.139 77.723  1.00 108.03 ? 207 LEU S N   1 
ATOM   6426 C CA  . LEU D 4 219 ? 133.294 163.007 78.238  1.00 110.20 ? 207 LEU S CA  1 
ATOM   6427 C C   . LEU D 4 219 ? 131.982 162.706 77.531  1.00 108.76 ? 207 LEU S C   1 
ATOM   6428 O O   . LEU D 4 219 ? 131.935 162.629 76.300  1.00 112.51 ? 207 LEU S O   1 
ATOM   6429 C CB  . LEU D 4 219 ? 133.668 164.478 78.057  1.00 113.44 ? 207 LEU S CB  1 
ATOM   6430 C CG  . LEU D 4 219 ? 134.310 165.147 79.271  1.00 113.42 ? 207 LEU S CG  1 
ATOM   6431 C CD1 . LEU D 4 219 ? 133.400 165.046 80.485  1.00 113.17 ? 207 LEU S CD1 1 
ATOM   6432 C CD2 . LEU D 4 219 ? 135.655 164.516 79.559  1.00 112.30 ? 207 LEU S CD2 1 
ATOM   6433 N N   . GLU D 4 220 ? 130.923 162.534 78.310  1.00 106.29 ? 208 GLU S N   1 
ATOM   6434 C CA  . GLU D 4 220 ? 129.601 162.234 77.788  1.00 108.22 ? 208 GLU S CA  1 
ATOM   6435 C C   . GLU D 4 220 ? 128.676 163.424 78.000  1.00 107.21 ? 208 GLU S C   1 
ATOM   6436 O O   . GLU D 4 220 ? 129.030 164.415 78.644  1.00 107.72 ? 208 GLU S O   1 
ATOM   6437 C CB  . GLU D 4 220 ? 129.026 160.980 78.455  1.00 111.54 ? 208 GLU S CB  1 
ATOM   6438 C CG  . GLU D 4 220 ? 129.411 159.674 77.774  1.00 114.15 ? 208 GLU S CG  1 
ATOM   6439 C CD  . GLU D 4 220 ? 130.873 159.628 77.373  1.00 116.05 ? 208 GLU S CD  1 
ATOM   6440 O OE1 . GLU D 4 220 ? 131.725 159.373 78.248  1.00 116.18 ? 208 GLU S OE1 1 
ATOM   6441 O OE2 . GLU D 4 220 ? 131.171 159.844 76.180  1.00 116.84 ? 208 GLU S OE2 1 
ATOM   6442 N N   . ALA D 4 221 ? 127.471 163.314 77.439  1.00 111.78 ? 209 ALA S N   1 
ATOM   6443 C CA  . ALA D 4 221 ? 126.496 164.388 77.575  1.00 115.29 ? 209 ALA S CA  1 
ATOM   6444 C C   . ALA D 4 221 ? 126.027 164.544 79.014  1.00 114.82 ? 209 ALA S C   1 
ATOM   6445 O O   . ALA D 4 221 ? 125.712 165.659 79.444  1.00 117.79 ? 209 ALA S O   1 
ATOM   6446 C CB  . ALA D 4 221 ? 125.304 164.138 76.653  1.00 115.20 ? 209 ALA S CB  1 
ATOM   6447 N N   . GLU D 4 222 ? 125.975 163.451 79.769  1.00 109.67 ? 210 GLU S N   1 
ATOM   6448 C CA  . GLU D 4 222 ? 125.494 163.477 81.142  1.00 113.11 ? 210 GLU S CA  1 
ATOM   6449 C C   . GLU D 4 222 ? 126.601 163.724 82.159  1.00 115.08 ? 210 GLU S C   1 
ATOM   6450 O O   . GLU D 4 222 ? 126.316 163.780 83.359  1.00 116.06 ? 210 GLU S O   1 
ATOM   6451 C CB  . GLU D 4 222 ? 124.774 162.167 81.469  1.00 112.46 ? 210 GLU S CB  1 
ATOM   6452 C CG  . GLU D 4 222 ? 123.571 161.893 80.583  1.00 113.58 ? 210 GLU S CG  1 
ATOM   6453 C CD  . GLU D 4 222 ? 122.505 161.074 81.283  1.00 117.48 ? 210 GLU S CD  1 
ATOM   6454 O OE1 . GLU D 4 222 ? 122.709 160.715 82.462  1.00 118.75 ? 210 GLU S OE1 1 
ATOM   6455 O OE2 . GLU D 4 222 ? 121.464 160.790 80.655  1.00 116.84 ? 210 GLU S OE2 1 
ATOM   6456 N N   . ASP D 4 223 ? 127.848 163.870 81.717  1.00 108.52 ? 211 ASP S N   1 
ATOM   6457 C CA  . ASP D 4 223 ? 128.945 164.182 82.622  1.00 105.04 ? 211 ASP S CA  1 
ATOM   6458 C C   . ASP D 4 223 ? 129.094 165.674 82.879  1.00 103.44 ? 211 ASP S C   1 
ATOM   6459 O O   . ASP D 4 223 ? 129.970 166.069 83.655  1.00 104.37 ? 211 ASP S O   1 
ATOM   6460 C CB  . ASP D 4 223 ? 130.256 163.619 82.073  1.00 106.67 ? 211 ASP S CB  1 
ATOM   6461 C CG  . ASP D 4 223 ? 130.293 162.108 82.103  1.00 111.81 ? 211 ASP S CG  1 
ATOM   6462 O OD1 . ASP D 4 223 ? 129.209 161.489 82.121  1.00 114.00 ? 211 ASP S OD1 1 
ATOM   6463 O OD2 . ASP D 4 223 ? 131.404 161.537 82.109  1.00 113.43 ? 211 ASP S OD2 1 
ATOM   6464 N N   . VAL D 4 224 ? 128.270 166.507 82.241  1.00 99.18  ? 212 VAL S N   1 
ATOM   6465 C CA  . VAL D 4 224 ? 128.303 167.936 82.508  1.00 100.22 ? 212 VAL S CA  1 
ATOM   6466 C C   . VAL D 4 224 ? 127.875 168.193 83.951  1.00 105.25 ? 212 VAL S C   1 
ATOM   6467 O O   . VAL D 4 224 ? 127.114 167.418 84.546  1.00 107.62 ? 212 VAL S O   1 
ATOM   6468 C CB  . VAL D 4 224 ? 127.401 168.684 81.510  1.00 103.19 ? 212 VAL S CB  1 
ATOM   6469 C CG1 . VAL D 4 224 ? 125.959 168.720 81.998  1.00 104.08 ? 212 VAL S CG1 1 
ATOM   6470 C CG2 . VAL D 4 224 ? 127.916 170.087 81.262  1.00 104.30 ? 212 VAL S CG2 1 
ATOM   6471 N N   . GLY D 4 225 ? 128.388 169.270 84.531  1.00 109.30 ? 213 GLY S N   1 
ATOM   6472 C CA  . GLY D 4 225 ? 128.002 169.633 85.876  1.00 105.92 ? 213 GLY S CA  1 
ATOM   6473 C C   . GLY D 4 225 ? 129.216 169.885 86.738  1.00 106.45 ? 213 GLY S C   1 
ATOM   6474 O O   . GLY D 4 225 ? 130.334 170.025 86.250  1.00 111.12 ? 213 GLY S O   1 
ATOM   6475 N N   . VAL D 4 226 ? 128.997 169.940 88.046  1.00 87.48  ? 214 VAL S N   1 
ATOM   6476 C CA  . VAL D 4 226 ? 130.054 170.285 88.986  1.00 86.74  ? 214 VAL S CA  1 
ATOM   6477 C C   . VAL D 4 226 ? 130.561 169.026 89.674  1.00 90.84  ? 214 VAL S C   1 
ATOM   6478 O O   . VAL D 4 226 ? 129.850 168.023 89.799  1.00 97.98  ? 214 VAL S O   1 
ATOM   6479 C CB  . VAL D 4 226 ? 129.560 171.331 90.005  1.00 88.69  ? 214 VAL S CB  1 
ATOM   6480 C CG1 . VAL D 4 226 ? 128.856 172.464 89.285  1.00 91.60  ? 214 VAL S CG1 1 
ATOM   6481 C CG2 . VAL D 4 226 ? 128.617 170.692 90.991  1.00 89.99  ? 214 VAL S CG2 1 
ATOM   6482 N N   . TYR D 4 227 ? 131.825 169.066 90.090  1.00 86.22  ? 215 TYR S N   1 
ATOM   6483 C CA  . TYR D 4 227 ? 132.477 167.969 90.790  1.00 81.75  ? 215 TYR S CA  1 
ATOM   6484 C C   . TYR D 4 227 ? 133.002 168.470 92.126  1.00 83.98  ? 215 TYR S C   1 
ATOM   6485 O O   . TYR D 4 227 ? 133.545 169.578 92.213  1.00 91.87  ? 215 TYR S O   1 
ATOM   6486 C CB  . TYR D 4 227 ? 133.646 167.369 89.986  1.00 83.51  ? 215 TYR S CB  1 
ATOM   6487 C CG  . TYR D 4 227 ? 133.282 166.630 88.711  1.00 84.90  ? 215 TYR S CG  1 
ATOM   6488 C CD1 . TYR D 4 227 ? 132.223 167.035 87.915  1.00 90.52  ? 215 TYR S CD1 1 
ATOM   6489 C CD2 . TYR D 4 227 ? 133.998 165.511 88.316  1.00 85.81  ? 215 TYR S CD2 1 
ATOM   6490 C CE1 . TYR D 4 227 ? 131.895 166.363 86.763  1.00 87.62  ? 215 TYR S CE1 1 
ATOM   6491 C CE2 . TYR D 4 227 ? 133.673 164.829 87.164  1.00 88.65  ? 215 TYR S CE2 1 
ATOM   6492 C CZ  . TYR D 4 227 ? 132.619 165.260 86.392  1.00 89.80  ? 215 TYR S CZ  1 
ATOM   6493 O OH  . TYR D 4 227 ? 132.281 164.590 85.240  1.00 98.52  ? 215 TYR S OH  1 
ATOM   6494 N N   . TYR D 4 228 ? 132.845 167.650 93.161  1.00 75.51  ? 216 TYR S N   1 
ATOM   6495 C CA  . TYR D 4 228 ? 133.322 167.966 94.498  1.00 85.34  ? 216 TYR S CA  1 
ATOM   6496 C C   . TYR D 4 228 ? 134.217 166.848 95.009  1.00 84.69  ? 216 TYR S C   1 
ATOM   6497 O O   . TYR D 4 228 ? 133.979 165.671 94.725  1.00 87.19  ? 216 TYR S O   1 
ATOM   6498 C CB  . TYR D 4 228 ? 132.163 168.170 95.475  1.00 87.49  ? 216 TYR S CB  1 
ATOM   6499 C CG  . TYR D 4 228 ? 131.180 169.239 95.072  1.00 84.85  ? 216 TYR S CG  1 
ATOM   6500 C CD1 . TYR D 4 228 ? 131.513 170.581 95.152  1.00 84.81  ? 216 TYR S CD1 1 
ATOM   6501 C CD2 . TYR D 4 228 ? 129.908 168.908 94.639  1.00 88.18  ? 216 TYR S CD2 1 
ATOM   6502 C CE1 . TYR D 4 228 ? 130.616 171.560 94.792  1.00 86.41  ? 216 TYR S CE1 1 
ATOM   6503 C CE2 . TYR D 4 228 ? 129.003 169.878 94.285  1.00 88.63  ? 216 TYR S CE2 1 
ATOM   6504 C CZ  . TYR D 4 228 ? 129.362 171.203 94.361  1.00 87.43  ? 216 TYR S CZ  1 
ATOM   6505 O OH  . TYR D 4 228 ? 128.458 172.174 94.001  1.00 92.02  ? 216 TYR S OH  1 
ATOM   6506 N N   . CYS D 4 229 ? 135.244 167.223 95.765  1.00 77.26  ? 217 CYS S N   1 
ATOM   6507 C CA  . CYS D 4 229 ? 136.090 166.279 96.481  1.00 75.00  ? 217 CYS S CA  1 
ATOM   6508 C C   . CYS D 4 229 ? 135.900 166.498 97.974  1.00 77.45  ? 217 CYS S C   1 
ATOM   6509 O O   . CYS D 4 229 ? 135.906 167.641 98.441  1.00 86.61  ? 217 CYS S O   1 
ATOM   6510 C CB  . CYS D 4 229 ? 137.565 166.441 96.095  1.00 80.37  ? 217 CYS S CB  1 
ATOM   6511 S SG  . CYS D 4 229 ? 138.330 168.021 96.557  1.00 99.96  ? 217 CYS S SG  1 
ATOM   6512 N N   . MET D 4 230 ? 135.714 165.411 98.716  1.00 74.95  ? 218 MET S N   1 
ATOM   6513 C CA  . MET D 4 230 ? 135.486 165.494 100.148 1.00 79.46  ? 218 MET S CA  1 
ATOM   6514 C C   . MET D 4 230 ? 136.419 164.532 100.867 1.00 84.21  ? 218 MET S C   1 
ATOM   6515 O O   . MET D 4 230 ? 136.724 163.453 100.361 1.00 87.78  ? 218 MET S O   1 
ATOM   6516 C CB  . MET D 4 230 ? 134.027 165.176 100.486 1.00 73.94  ? 218 MET S CB  1 
ATOM   6517 C CG  . MET D 4 230 ? 133.854 164.343 101.732 1.00 80.23  ? 218 MET S CG  1 
ATOM   6518 S SD  . MET D 4 230 ? 132.147 163.962 102.120 1.00 87.69  ? 218 MET S SD  1 
ATOM   6519 C CE  . MET D 4 230 ? 132.404 162.534 103.155 1.00 85.80  ? 218 MET S CE  1 
ATOM   6520 N N   . GLN D 4 231 ? 136.884 164.930 102.044 1.00 87.88  ? 219 GLN S N   1 
ATOM   6521 C CA  . GLN D 4 231 ? 137.738 164.065 102.842 1.00 83.20  ? 219 GLN S CA  1 
ATOM   6522 C C   . GLN D 4 231 ? 136.934 163.419 103.961 1.00 88.74  ? 219 GLN S C   1 
ATOM   6523 O O   . GLN D 4 231 ? 135.873 163.907 104.360 1.00 94.42  ? 219 GLN S O   1 
ATOM   6524 C CB  . GLN D 4 231 ? 138.956 164.856 103.358 1.00 84.39  ? 219 GLN S CB  1 
ATOM   6525 C CG  . GLN D 4 231 ? 138.796 166.009 104.391 1.00 93.40  ? 219 GLN S CG  1 
ATOM   6526 C CD  . GLN D 4 231 ? 138.277 165.662 105.787 1.00 97.67  ? 219 GLN S CD  1 
ATOM   6527 O OE1 . GLN D 4 231 ? 137.940 164.529 106.101 1.00 101.80 ? 219 GLN S OE1 1 
ATOM   6528 N NE2 . GLN D 4 231 ? 138.230 166.673 106.642 1.00 92.59  ? 219 GLN S NE2 1 
ATOM   6529 N N   . HIS D 4 232 ? 137.457 162.298 104.464 1.00 75.40  ? 220 HIS S N   1 
ATOM   6530 C CA  . HIS D 4 232 ? 136.820 161.582 105.562 1.00 70.44  ? 220 HIS S CA  1 
ATOM   6531 C C   . HIS D 4 232 ? 137.814 161.169 106.641 1.00 77.87  ? 220 HIS S C   1 
ATOM   6532 O O   . HIS D 4 232 ? 137.489 160.301 107.460 1.00 81.27  ? 220 HIS S O   1 
ATOM   6533 C CB  . HIS D 4 232 ? 136.081 160.348 105.038 1.00 65.88  ? 220 HIS S CB  1 
ATOM   6534 C CG  . HIS D 4 232 ? 134.805 160.050 105.762 1.00 66.98  ? 220 HIS S CG  1 
ATOM   6535 N ND1 . HIS D 4 232 ? 134.771 159.646 107.078 1.00 72.68  ? 220 HIS S ND1 1 
ATOM   6536 C CD2 . HIS D 4 232 ? 133.517 160.092 105.348 1.00 72.02  ? 220 HIS S CD2 1 
ATOM   6537 C CE1 . HIS D 4 232 ? 133.517 159.452 107.444 1.00 71.77  ? 220 HIS S CE1 1 
ATOM   6538 N NE2 . HIS D 4 232 ? 132.737 159.716 106.413 1.00 72.89  ? 220 HIS S NE2 1 
ATOM   6539 N N   . LEU D 4 233 ? 139.013 161.755 106.667 1.00 75.68  ? 221 LEU S N   1 
ATOM   6540 C CA  . LEU D 4 233 ? 140.005 161.367 107.665 1.00 67.22  ? 221 LEU S CA  1 
ATOM   6541 C C   . LEU D 4 233 ? 139.644 161.912 109.040 1.00 77.58  ? 221 LEU S C   1 
ATOM   6542 O O   . LEU D 4 233 ? 139.542 161.156 110.012 1.00 84.89  ? 221 LEU S O   1 
ATOM   6543 C CB  . LEU D 4 233 ? 141.388 161.856 107.242 1.00 69.42  ? 221 LEU S CB  1 
ATOM   6544 C CG  . LEU D 4 233 ? 142.537 161.333 108.100 1.00 78.81  ? 221 LEU S CG  1 
ATOM   6545 C CD1 . LEU D 4 233 ? 142.484 159.821 108.166 1.00 82.25  ? 221 LEU S CD1 1 
ATOM   6546 C CD2 . LEU D 4 233 ? 143.878 161.803 107.563 1.00 79.49  ? 221 LEU S CD2 1 
ATOM   6547 N N   . GLU D 4 234 ? 139.446 163.223 109.139 1.00 93.21  ? 222 GLU S N   1 
ATOM   6548 C CA  . GLU D 4 234 ? 139.021 163.873 110.370 1.00 90.18  ? 222 GLU S CA  1 
ATOM   6549 C C   . GLU D 4 234 ? 137.578 164.314 110.202 1.00 84.63  ? 222 GLU S C   1 
ATOM   6550 O O   . GLU D 4 234 ? 137.218 164.890 109.170 1.00 91.50  ? 222 GLU S O   1 
ATOM   6551 C CB  . GLU D 4 234 ? 139.916 165.066 110.714 1.00 97.19  ? 222 GLU S CB  1 
ATOM   6552 C CG  . GLU D 4 234 ? 141.106 164.705 111.589 1.00 97.97  ? 222 GLU S CG  1 
ATOM   6553 C CD  . GLU D 4 234 ? 142.298 164.233 110.788 1.00 101.88 ? 222 GLU S CD  1 
ATOM   6554 O OE1 . GLU D 4 234 ? 142.216 164.241 109.542 1.00 106.97 ? 222 GLU S OE1 1 
ATOM   6555 O OE2 . GLU D 4 234 ? 143.315 163.849 111.402 1.00 98.44  ? 222 GLU S OE2 1 
ATOM   6556 N N   . TYR D 4 235 ? 136.761 164.040 111.208 1.00 77.48  ? 223 TYR S N   1 
ATOM   6557 C CA  . TYR D 4 235 ? 135.325 164.002 110.974 1.00 89.95  ? 223 TYR S CA  1 
ATOM   6558 C C   . TYR D 4 235 ? 134.714 165.362 110.635 1.00 88.62  ? 223 TYR S C   1 
ATOM   6559 O O   . TYR D 4 235 ? 133.637 165.395 110.029 1.00 97.67  ? 223 TYR S O   1 
ATOM   6560 C CB  . TYR D 4 235 ? 134.585 163.375 112.152 1.00 85.03  ? 223 TYR S CB  1 
ATOM   6561 C CG  . TYR D 4 235 ? 133.445 162.548 111.620 1.00 82.41  ? 223 TYR S CG  1 
ATOM   6562 C CD1 . TYR D 4 235 ? 132.244 163.122 111.240 1.00 82.58  ? 223 TYR S CD1 1 
ATOM   6563 C CD2 . TYR D 4 235 ? 133.618 161.192 111.407 1.00 85.07  ? 223 TYR S CD2 1 
ATOM   6564 C CE1 . TYR D 4 235 ? 131.230 162.353 110.711 1.00 83.47  ? 223 TYR S CE1 1 
ATOM   6565 C CE2 . TYR D 4 235 ? 132.619 160.420 110.885 1.00 89.88  ? 223 TYR S CE2 1 
ATOM   6566 C CZ  . TYR D 4 235 ? 131.427 160.999 110.538 1.00 88.23  ? 223 TYR S CZ  1 
ATOM   6567 O OH  . TYR D 4 235 ? 130.439 160.205 110.013 1.00 88.15  ? 223 TYR S OH  1 
ATOM   6568 N N   . PRO D 4 236 ? 135.324 166.504 110.987 1.00 74.79  ? 224 PRO S N   1 
ATOM   6569 C CA  . PRO D 4 236 ? 134.814 167.757 110.416 1.00 78.72  ? 224 PRO S CA  1 
ATOM   6570 C C   . PRO D 4 236 ? 135.013 167.779 108.909 1.00 90.14  ? 224 PRO S C   1 
ATOM   6571 O O   . PRO D 4 236 ? 135.910 168.451 108.390 1.00 94.36  ? 224 PRO S O   1 
ATOM   6572 C CB  . PRO D 4 236 ? 135.646 168.834 111.118 1.00 79.04  ? 224 PRO S CB  1 
ATOM   6573 C CG  . PRO D 4 236 ? 135.995 168.232 112.411 1.00 84.98  ? 224 PRO S CG  1 
ATOM   6574 C CD  . PRO D 4 236 ? 136.190 166.767 112.153 1.00 80.95  ? 224 PRO S CD  1 
ATOM   6575 N N   . LEU D 4 237 ? 134.166 167.021 108.210 1.00 90.86  ? 225 LEU S N   1 
ATOM   6576 C CA  . LEU D 4 237 ? 134.294 166.841 106.770 1.00 80.74  ? 225 LEU S CA  1 
ATOM   6577 C C   . LEU D 4 237 ? 134.168 168.175 106.054 1.00 87.13  ? 225 LEU S C   1 
ATOM   6578 O O   . LEU D 4 237 ? 133.270 168.968 106.345 1.00 95.55  ? 225 LEU S O   1 
ATOM   6579 C CB  . LEU D 4 237 ? 133.219 165.880 106.262 1.00 79.43  ? 225 LEU S CB  1 
ATOM   6580 C CG  . LEU D 4 237 ? 132.916 164.630 107.089 1.00 81.82  ? 225 LEU S CG  1 
ATOM   6581 C CD1 . LEU D 4 237 ? 131.644 163.963 106.599 1.00 82.55  ? 225 LEU S CD1 1 
ATOM   6582 C CD2 . LEU D 4 237 ? 134.079 163.659 107.060 1.00 82.72  ? 225 LEU S CD2 1 
ATOM   6583 N N   . THR D 4 238 ? 135.071 168.421 105.111 1.00 80.18  ? 226 THR S N   1 
ATOM   6584 C CA  . THR D 4 238 ? 135.064 169.654 104.339 1.00 86.79  ? 226 THR S CA  1 
ATOM   6585 C C   . THR D 4 238 ? 135.065 169.308 102.861 1.00 87.72  ? 226 THR S C   1 
ATOM   6586 O O   . THR D 4 238 ? 135.981 168.636 102.379 1.00 91.45  ? 226 THR S O   1 
ATOM   6587 C CB  . THR D 4 238 ? 136.266 170.531 104.689 1.00 92.91  ? 226 THR S CB  1 
ATOM   6588 O OG1 . THR D 4 238 ? 137.405 169.701 104.944 1.00 93.72  ? 226 THR S OG1 1 
ATOM   6589 C CG2 . THR D 4 238 ? 135.967 171.371 105.923 1.00 90.01  ? 226 THR S CG2 1 
ATOM   6590 N N   . PHE D 4 239 ? 134.040 169.764 102.151 1.00 81.25  ? 227 PHE S N   1 
ATOM   6591 C CA  . PHE D 4 239 ? 133.970 169.583 100.714 1.00 80.24  ? 227 PHE S CA  1 
ATOM   6592 C C   . PHE D 4 239 ? 134.858 170.604 100.011 1.00 83.10  ? 227 PHE S C   1 
ATOM   6593 O O   . PHE D 4 239 ? 135.242 171.630 100.577 1.00 87.76  ? 227 PHE S O   1 
ATOM   6594 C CB  . PHE D 4 239 ? 132.530 169.722 100.226 1.00 77.96  ? 227 PHE S CB  1 
ATOM   6595 C CG  . PHE D 4 239 ? 131.642 168.583 100.626 1.00 70.77  ? 227 PHE S CG  1 
ATOM   6596 C CD1 . PHE D 4 239 ? 131.077 168.539 101.886 1.00 75.57  ? 227 PHE S CD1 1 
ATOM   6597 C CD2 . PHE D 4 239 ? 131.364 167.562 99.739  1.00 74.64  ? 227 PHE S CD2 1 
ATOM   6598 C CE1 . PHE D 4 239 ? 130.258 167.496 102.253 1.00 81.48  ? 227 PHE S CE1 1 
ATOM   6599 C CE2 . PHE D 4 239 ? 130.547 166.518 100.103 1.00 79.07  ? 227 PHE S CE2 1 
ATOM   6600 C CZ  . PHE D 4 239 ? 129.992 166.485 101.359 1.00 81.74  ? 227 PHE S CZ  1 
ATOM   6601 N N   . GLY D 4 240 ? 135.187 170.308 98.758  1.00 83.38  ? 228 GLY S N   1 
ATOM   6602 C CA  . GLY D 4 240 ? 135.954 171.224 97.947  1.00 84.51  ? 228 GLY S CA  1 
ATOM   6603 C C   . GLY D 4 240 ? 135.097 172.337 97.385  1.00 87.03  ? 228 GLY S C   1 
ATOM   6604 O O   . GLY D 4 240 ? 133.881 172.391 97.569  1.00 87.81  ? 228 GLY S O   1 
ATOM   6605 N N   . ALA D 4 241 ? 135.761 173.258 96.686  1.00 87.91  ? 229 ALA S N   1 
ATOM   6606 C CA  . ALA D 4 241 ? 135.042 174.355 96.049  1.00 85.97  ? 229 ALA S CA  1 
ATOM   6607 C C   . ALA D 4 241 ? 134.109 173.842 94.961  1.00 85.27  ? 229 ALA S C   1 
ATOM   6608 O O   . ALA D 4 241 ? 132.977 174.321 94.825  1.00 80.84  ? 229 ALA S O   1 
ATOM   6609 C CB  . ALA D 4 241 ? 136.031 175.370 95.477  1.00 86.93  ? 229 ALA S CB  1 
ATOM   6610 N N   . GLY D 4 242 ? 134.564 172.869 94.179  1.00 101.81 ? 230 GLY S N   1 
ATOM   6611 C CA  . GLY D 4 242 ? 133.756 172.319 93.111  1.00 101.35 ? 230 GLY S CA  1 
ATOM   6612 C C   . GLY D 4 242 ? 134.161 172.831 91.746  1.00 103.90 ? 230 GLY S C   1 
ATOM   6613 O O   . GLY D 4 242 ? 134.020 174.023 91.458  1.00 108.82 ? 230 GLY S O   1 
ATOM   6614 N N   . THR D 4 243 ? 134.667 171.943 90.897  1.00 98.64  ? 231 THR S N   1 
ATOM   6615 C CA  . THR D 4 243 ? 135.080 172.301 89.548  1.00 98.28  ? 231 THR S CA  1 
ATOM   6616 C C   . THR D 4 243 ? 133.934 172.021 88.588  1.00 99.21  ? 231 THR S C   1 
ATOM   6617 O O   . THR D 4 243 ? 133.397 170.912 88.568  1.00 106.21 ? 231 THR S O   1 
ATOM   6618 C CB  . THR D 4 243 ? 136.320 171.516 89.126  1.00 104.92 ? 231 THR S CB  1 
ATOM   6619 O OG1 . THR D 4 243 ? 135.997 170.123 89.051  1.00 111.23 ? 231 THR S OG1 1 
ATOM   6620 C CG2 . THR D 4 243 ? 137.441 171.715 90.131  1.00 103.21 ? 231 THR S CG2 1 
ATOM   6621 N N   . LYS D 4 244 ? 133.560 173.022 87.801  1.00 100.16 ? 232 LYS S N   1 
ATOM   6622 C CA  . LYS D 4 244 ? 132.399 172.927 86.927  1.00 101.89 ? 232 LYS S CA  1 
ATOM   6623 C C   . LYS D 4 244 ? 132.861 172.643 85.503  1.00 105.08 ? 232 LYS S C   1 
ATOM   6624 O O   . LYS D 4 244 ? 133.644 173.412 84.935  1.00 110.34 ? 232 LYS S O   1 
ATOM   6625 C CB  . LYS D 4 244 ? 131.576 174.212 86.984  1.00 106.00 ? 232 LYS S CB  1 
ATOM   6626 C CG  . LYS D 4 244 ? 130.258 174.142 86.239  1.00 106.69 ? 232 LYS S CG  1 
ATOM   6627 C CD  . LYS D 4 244 ? 129.523 175.469 86.307  1.00 109.55 ? 232 LYS S CD  1 
ATOM   6628 C CE  . LYS D 4 244 ? 128.263 175.447 85.459  1.00 107.98 ? 232 LYS S CE  1 
ATOM   6629 N NZ  . LYS D 4 244 ? 127.568 176.763 85.467  1.00 106.16 ? 232 LYS S NZ  1 
ATOM   6630 N N   . LEU D 4 245 ? 132.378 171.542 84.933  1.00 110.70 ? 233 LEU S N   1 
ATOM   6631 C CA  . LEU D 4 245 ? 132.656 171.163 83.556  1.00 111.67 ? 233 LEU S CA  1 
ATOM   6632 C C   . LEU D 4 245 ? 131.414 171.442 82.724  1.00 114.64 ? 233 LEU S C   1 
ATOM   6633 O O   . LEU D 4 245 ? 130.325 170.948 83.046  1.00 115.81 ? 233 LEU S O   1 
ATOM   6634 C CB  . LEU D 4 245 ? 133.046 169.689 83.458  1.00 111.87 ? 233 LEU S CB  1 
ATOM   6635 C CG  . LEU D 4 245 ? 134.272 169.237 84.249  1.00 114.31 ? 233 LEU S CG  1 
ATOM   6636 C CD1 . LEU D 4 245 ? 134.735 167.871 83.774  1.00 113.96 ? 233 LEU S CD1 1 
ATOM   6637 C CD2 . LEU D 4 245 ? 135.395 170.253 84.136  1.00 115.74 ? 233 LEU S CD2 1 
ATOM   6638 N N   . GLU D 4 246 ? 131.580 172.240 81.670  1.00 127.76 ? 234 GLU S N   1 
ATOM   6639 C CA  . GLU D 4 246 ? 130.504 172.585 80.755  1.00 128.19 ? 234 GLU S CA  1 
ATOM   6640 C C   . GLU D 4 246 ? 131.029 172.541 79.326  1.00 126.74 ? 234 GLU S C   1 
ATOM   6641 O O   . GLU D 4 246 ? 132.234 172.641 79.081  1.00 124.57 ? 234 GLU S O   1 
ATOM   6642 C CB  . GLU D 4 246 ? 129.913 173.976 81.043  1.00 124.74 ? 234 GLU S CB  1 
ATOM   6643 C CG  . GLU D 4 246 ? 130.922 175.123 81.080  1.00 126.31 ? 234 GLU S CG  1 
ATOM   6644 C CD  . GLU D 4 246 ? 131.786 175.132 82.326  1.00 128.24 ? 234 GLU S CD  1 
ATOM   6645 O OE1 . GLU D 4 246 ? 131.464 174.397 83.282  1.00 127.22 ? 234 GLU S OE1 1 
ATOM   6646 O OE2 . GLU D 4 246 ? 132.789 175.875 82.348  1.00 130.21 ? 234 GLU S OE2 1 
ATOM   6647 N N   . LEU D 4 247 ? 130.105 172.395 78.383  1.00 116.22 ? 235 LEU S N   1 
ATOM   6648 C CA  . LEU D 4 247 ? 130.455 172.341 76.968  1.00 113.53 ? 235 LEU S CA  1 
ATOM   6649 C C   . LEU D 4 247 ? 131.020 173.673 76.487  1.00 112.96 ? 235 LEU S C   1 
ATOM   6650 O O   . LEU D 4 247 ? 131.073 173.937 75.286  1.00 111.65 ? 235 LEU S O   1 
ATOM   6651 C CB  . LEU D 4 247 ? 129.239 171.956 76.122  1.00 114.21 ? 235 LEU S CB  1 
ATOM   6652 C CG  . LEU D 4 247 ? 128.580 170.598 76.382  1.00 116.54 ? 235 LEU S CG  1 
ATOM   6653 C CD1 . LEU D 4 247 ? 129.621 169.544 76.734  1.00 116.45 ? 235 LEU S CD1 1 
ATOM   6654 C CD2 . LEU D 4 247 ? 127.509 170.694 77.461  1.00 114.68 ? 235 LEU S CD2 1 
ATOM   6655 N N   . ILE E 5 540 ? 147.758 125.695 178.439 1.00 127.19 ? 2   ILE R N   1 
ATOM   6656 C CA  . ILE E 5 540 ? 148.814 126.034 179.388 1.00 126.22 ? 2   ILE R CA  1 
ATOM   6657 C C   . ILE E 5 540 ? 150.135 125.294 179.099 1.00 125.35 ? 2   ILE R C   1 
ATOM   6658 O O   . ILE E 5 540 ? 151.178 125.943 179.024 1.00 124.39 ? 2   ILE R O   1 
ATOM   6659 C CB  . ILE E 5 540 ? 148.367 125.798 180.861 1.00 125.62 ? 2   ILE R CB  1 
ATOM   6660 C CG1 . ILE E 5 540 ? 146.931 126.282 181.101 1.00 125.32 ? 2   ILE R CG1 1 
ATOM   6661 C CG2 . ILE E 5 540 ? 149.328 126.478 181.822 1.00 125.02 ? 2   ILE R CG2 1 
ATOM   6662 C CD1 . ILE E 5 540 ? 145.855 125.235 180.855 1.00 123.55 ? 2   ILE R CD1 1 
ATOM   6663 N N   . PRO E 5 541 ? 150.121 123.966 178.947 1.00 129.34 ? 3   PRO R N   1 
ATOM   6664 C CA  . PRO E 5 541 ? 151.374 123.269 178.635 1.00 130.29 ? 3   PRO R CA  1 
ATOM   6665 C C   . PRO E 5 541 ? 151.942 123.708 177.295 1.00 130.36 ? 3   PRO R C   1 
ATOM   6666 O O   . PRO E 5 541 ? 151.214 123.976 176.337 1.00 129.30 ? 3   PRO R O   1 
ATOM   6667 C CB  . PRO E 5 541 ? 150.983 121.786 178.604 1.00 132.41 ? 3   PRO R CB  1 
ATOM   6668 C CG  . PRO E 5 541 ? 149.532 121.720 178.662 1.00 132.52 ? 3   PRO R CG  1 
ATOM   6669 C CD  . PRO E 5 541 ? 148.973 123.041 179.028 1.00 130.91 ? 3   PRO R CD  1 
ATOM   6670 N N   . ILE E 5 542 ? 153.273 123.773 177.241 1.00 132.93 ? 4   ILE R N   1 
ATOM   6671 C CA  . ILE E 5 542 ? 153.929 124.297 176.048 1.00 133.49 ? 4   ILE R CA  1 
ATOM   6672 C C   . ILE E 5 542 ? 153.850 123.317 174.880 1.00 132.69 ? 4   ILE R C   1 
ATOM   6673 O O   . ILE E 5 542 ? 153.871 123.736 173.715 1.00 131.79 ? 4   ILE R O   1 
ATOM   6674 C CB  . ILE E 5 542 ? 155.371 124.740 176.391 1.00 132.10 ? 4   ILE R CB  1 
ATOM   6675 C CG1 . ILE E 5 542 ? 156.283 123.614 176.929 1.00 133.17 ? 4   ILE R CG1 1 
ATOM   6676 C CG2 . ILE E 5 542 ? 155.343 125.899 177.381 1.00 131.53 ? 4   ILE R CG2 1 
ATOM   6677 C CD1 . ILE E 5 542 ? 156.665 122.480 175.989 1.00 132.58 ? 4   ILE R CD1 1 
ATOM   6678 N N   . GLN E 5 543 ? 153.742 122.014 175.154 1.00 141.09 ? 5   GLN R N   1 
ATOM   6679 C CA  . GLN E 5 543 ? 153.593 121.058 174.063 1.00 144.80 ? 5   GLN R CA  1 
ATOM   6680 C C   . GLN E 5 543 ? 152.258 121.233 173.354 1.00 145.41 ? 5   GLN R C   1 
ATOM   6681 O O   . GLN E 5 543 ? 152.196 121.146 172.123 1.00 145.78 ? 5   GLN R O   1 
ATOM   6682 C CB  . GLN E 5 543 ? 153.760 119.623 174.576 1.00 146.26 ? 5   GLN R CB  1 
ATOM   6683 C CG  . GLN E 5 543 ? 152.718 119.154 175.581 1.00 145.62 ? 5   GLN R CG  1 
ATOM   6684 C CD  . GLN E 5 543 ? 153.033 119.584 177.000 1.00 143.86 ? 5   GLN R CD  1 
ATOM   6685 O OE1 . GLN E 5 543 ? 153.669 120.614 177.225 1.00 142.30 ? 5   GLN R OE1 1 
ATOM   6686 N NE2 . GLN E 5 543 ? 152.588 118.792 177.969 1.00 143.63 ? 5   GLN R NE2 1 
ATOM   6687 N N   . LEU E 5 544 ? 151.189 121.504 174.105 1.00 136.47 ? 6   LEU R N   1 
ATOM   6688 C CA  . LEU E 5 544 ? 149.904 121.791 173.481 1.00 135.34 ? 6   LEU R CA  1 
ATOM   6689 C C   . LEU E 5 544 ? 149.992 123.034 172.606 1.00 132.55 ? 6   LEU R C   1 
ATOM   6690 O O   . LEU E 5 544 ? 149.471 123.052 171.485 1.00 132.79 ? 6   LEU R O   1 
ATOM   6691 C CB  . LEU E 5 544 ? 148.828 121.950 174.558 1.00 134.63 ? 6   LEU R CB  1 
ATOM   6692 C CG  . LEU E 5 544 ? 147.495 122.620 174.216 1.00 135.47 ? 6   LEU R CG  1 
ATOM   6693 C CD1 . LEU E 5 544 ? 146.366 121.945 174.975 1.00 134.15 ? 6   LEU R CD1 1 
ATOM   6694 C CD2 . LEU E 5 544 ? 147.530 124.105 174.550 1.00 135.62 ? 6   LEU R CD2 1 
ATOM   6695 N N   . THR E 5 545 ? 150.660 124.079 173.100 1.00 130.36 ? 7   THR R N   1 
ATOM   6696 C CA  . THR E 5 545 ? 150.784 125.311 172.329 1.00 134.12 ? 7   THR R CA  1 
ATOM   6697 C C   . THR E 5 545 ? 151.553 125.074 171.038 1.00 132.29 ? 7   THR R C   1 
ATOM   6698 O O   . THR E 5 545 ? 151.136 125.522 169.965 1.00 134.19 ? 7   THR R O   1 
ATOM   6699 C CB  . THR E 5 545 ? 151.471 126.392 173.163 1.00 137.71 ? 7   THR R CB  1 
ATOM   6700 O OG1 . THR E 5 545 ? 152.804 125.973 173.482 1.00 139.26 ? 7   THR R OG1 1 
ATOM   6701 C CG2 . THR E 5 545 ? 150.702 126.646 174.449 1.00 137.51 ? 7   THR R CG2 1 
ATOM   6702 N N   . VAL E 5 546 ? 152.680 124.363 171.117 1.00 128.65 ? 8   VAL R N   1 
ATOM   6703 C CA  . VAL E 5 546 ? 153.485 124.156 169.917 1.00 130.92 ? 8   VAL R CA  1 
ATOM   6704 C C   . VAL E 5 546 ? 152.763 123.237 168.937 1.00 132.45 ? 8   VAL R C   1 
ATOM   6705 O O   . VAL E 5 546 ? 152.861 123.415 167.717 1.00 129.91 ? 8   VAL R O   1 
ATOM   6706 C CB  . VAL E 5 546 ? 154.891 123.637 170.280 1.00 132.23 ? 8   VAL R CB  1 
ATOM   6707 C CG1 . VAL E 5 546 ? 154.847 122.213 170.810 1.00 133.40 ? 8   VAL R CG1 1 
ATOM   6708 C CG2 . VAL E 5 546 ? 155.815 123.737 169.075 1.00 132.30 ? 8   VAL R CG2 1 
ATOM   6709 N N   . PHE E 5 547 ? 152.011 122.256 169.444 1.00 137.73 ? 9   PHE R N   1 
ATOM   6710 C CA  . PHE E 5 547 ? 151.252 121.378 168.561 1.00 137.52 ? 9   PHE R CA  1 
ATOM   6711 C C   . PHE E 5 547 ? 150.156 122.149 167.837 1.00 135.92 ? 9   PHE R C   1 
ATOM   6712 O O   . PHE E 5 547 ? 150.006 122.045 166.615 1.00 137.43 ? 9   PHE R O   1 
ATOM   6713 C CB  . PHE E 5 547 ? 150.662 120.219 169.363 1.00 137.84 ? 9   PHE R CB  1 
ATOM   6714 C CG  . PHE E 5 547 ? 149.427 119.623 168.754 1.00 137.07 ? 9   PHE R CG  1 
ATOM   6715 C CD1 . PHE E 5 547 ? 149.522 118.754 167.682 1.00 137.04 ? 9   PHE R CD1 1 
ATOM   6716 C CD2 . PHE E 5 547 ? 148.172 119.931 169.252 1.00 136.62 ? 9   PHE R CD2 1 
ATOM   6717 C CE1 . PHE E 5 547 ? 148.391 118.198 167.119 1.00 135.98 ? 9   PHE R CE1 1 
ATOM   6718 C CE2 . PHE E 5 547 ? 147.035 119.382 168.690 1.00 137.05 ? 9   PHE R CE2 1 
ATOM   6719 C CZ  . PHE E 5 547 ? 147.146 118.513 167.623 1.00 136.35 ? 9   PHE R CZ  1 
ATOM   6720 N N   . PHE E 5 548 ? 149.376 122.936 168.574 1.00 120.44 ? 10  PHE R N   1 
ATOM   6721 C CA  . PHE E 5 548 ? 148.354 123.730 167.912 1.00 118.16 ? 10  PHE R CA  1 
ATOM   6722 C C   . PHE E 5 548 ? 148.964 124.744 166.955 1.00 120.41 ? 10  PHE R C   1 
ATOM   6723 O O   . PHE E 5 548 ? 148.371 125.040 165.915 1.00 120.47 ? 10  PHE R O   1 
ATOM   6724 C CB  . PHE E 5 548 ? 147.471 124.416 168.944 1.00 114.66 ? 10  PHE R CB  1 
ATOM   6725 C CG  . PHE E 5 548 ? 146.385 123.539 169.462 1.00 116.71 ? 10  PHE R CG  1 
ATOM   6726 C CD1 . PHE E 5 548 ? 145.216 123.381 168.745 1.00 118.52 ? 10  PHE R CD1 1 
ATOM   6727 C CD2 . PHE E 5 548 ? 146.536 122.859 170.654 1.00 118.53 ? 10  PHE R CD2 1 
ATOM   6728 C CE1 . PHE E 5 548 ? 144.212 122.568 169.211 1.00 118.83 ? 10  PHE R CE1 1 
ATOM   6729 C CE2 . PHE E 5 548 ? 145.535 122.049 171.130 1.00 120.42 ? 10  PHE R CE2 1 
ATOM   6730 C CZ  . PHE E 5 548 ? 144.371 121.901 170.408 1.00 120.97 ? 10  PHE R CZ  1 
ATOM   6731 N N   . MET E 5 549 ? 150.153 125.266 167.265 1.00 131.78 ? 11  MET R N   1 
ATOM   6732 C CA  . MET E 5 549 ? 150.777 126.239 166.373 1.00 132.31 ? 11  MET R CA  1 
ATOM   6733 C C   . MET E 5 549 ? 151.280 125.570 165.093 1.00 129.71 ? 11  MET R C   1 
ATOM   6734 O O   . MET E 5 549 ? 151.178 126.158 164.009 1.00 130.72 ? 11  MET R O   1 
ATOM   6735 C CB  . MET E 5 549 ? 151.881 127.000 167.135 1.00 130.69 ? 11  MET R CB  1 
ATOM   6736 C CG  . MET E 5 549 ? 152.897 127.897 166.366 1.00 128.58 ? 11  MET R CG  1 
ATOM   6737 S SD  . MET E 5 549 ? 153.848 127.334 164.941 1.00 138.01 ? 11  MET R SD  1 
ATOM   6738 C CE  . MET E 5 549 ? 154.818 126.054 165.721 1.00 133.14 ? 11  MET R CE  1 
ATOM   6739 N N   . ILE E 5 550 ? 151.816 124.347 165.178 1.00 123.09 ? 12  ILE R N   1 
ATOM   6740 C CA  . ILE E 5 550 ? 152.214 123.662 163.948 1.00 125.34 ? 12  ILE R CA  1 
ATOM   6741 C C   . ILE E 5 550 ? 150.988 123.308 163.111 1.00 127.09 ? 12  ILE R C   1 
ATOM   6742 O O   . ILE E 5 550 ? 151.014 123.406 161.875 1.00 126.76 ? 12  ILE R O   1 
ATOM   6743 C CB  . ILE E 5 550 ? 153.088 122.417 164.222 1.00 128.48 ? 12  ILE R CB  1 
ATOM   6744 C CG1 . ILE E 5 550 ? 152.428 121.438 165.182 1.00 128.49 ? 12  ILE R CG1 1 
ATOM   6745 C CG2 . ILE E 5 550 ? 154.462 122.794 164.722 1.00 127.01 ? 12  ILE R CG2 1 
ATOM   6746 C CD1 . ILE E 5 550 ? 153.123 120.115 165.242 1.00 126.28 ? 12  ILE R CD1 1 
ATOM   6747 N N   . ILE E 5 551 ? 149.892 122.890 163.754 1.00 127.99 ? 13  ILE R N   1 
ATOM   6748 C CA  . ILE E 5 551 ? 148.696 122.598 162.966 1.00 127.01 ? 13  ILE R CA  1 
ATOM   6749 C C   . ILE E 5 551 ? 148.139 123.875 162.347 1.00 122.84 ? 13  ILE R C   1 
ATOM   6750 O O   . ILE E 5 551 ? 147.646 123.862 161.214 1.00 125.20 ? 13  ILE R O   1 
ATOM   6751 C CB  . ILE E 5 551 ? 147.638 121.831 163.788 1.00 127.33 ? 13  ILE R CB  1 
ATOM   6752 C CG1 . ILE E 5 551 ? 146.734 122.772 164.589 1.00 126.18 ? 13  ILE R CG1 1 
ATOM   6753 C CG2 . ILE E 5 551 ? 148.271 120.717 164.619 1.00 127.32 ? 13  ILE R CG2 1 
ATOM   6754 C CD1 . ILE E 5 551 ? 145.411 122.152 164.967 1.00 124.17 ? 13  ILE R CD1 1 
ATOM   6755 N N   . TYR E 5 552 ? 148.245 125.006 163.050 1.00 110.76 ? 14  TYR R N   1 
ATOM   6756 C CA  . TYR E 5 552 ? 147.819 126.265 162.447 1.00 113.54 ? 14  TYR R CA  1 
ATOM   6757 C C   . TYR E 5 552 ? 148.675 126.616 161.241 1.00 114.30 ? 14  TYR R C   1 
ATOM   6758 O O   . TYR E 5 552 ? 148.151 127.043 160.210 1.00 115.19 ? 14  TYR R O   1 
ATOM   6759 C CB  . TYR E 5 552 ? 147.821 127.398 163.483 1.00 115.77 ? 14  TYR R CB  1 
ATOM   6760 C CG  . TYR E 5 552 ? 147.304 128.737 162.958 1.00 112.01 ? 14  TYR R CG  1 
ATOM   6761 C CD1 . TYR E 5 552 ? 147.935 129.398 161.907 1.00 109.09 ? 14  TYR R CD1 1 
ATOM   6762 C CD2 . TYR E 5 552 ? 146.137 129.291 163.450 1.00 111.66 ? 14  TYR R CD2 1 
ATOM   6763 C CE1 . TYR E 5 552 ? 147.461 130.583 161.411 1.00 110.92 ? 14  TYR R CE1 1 
ATOM   6764 C CE2 . TYR E 5 552 ? 145.651 130.481 162.948 1.00 110.64 ? 14  TYR R CE2 1 
ATOM   6765 C CZ  . TYR E 5 552 ? 146.315 131.122 161.934 1.00 112.25 ? 14  TYR R CZ  1 
ATOM   6766 O OH  . TYR E 5 552 ? 145.823 132.309 161.442 1.00 114.80 ? 14  TYR R OH  1 
ATOM   6767 N N   . VAL E 5 553 ? 149.997 126.486 161.355 1.00 122.35 ? 15  VAL R N   1 
ATOM   6768 C CA  . VAL E 5 553 ? 150.812 126.893 160.217 1.00 121.29 ? 15  VAL R CA  1 
ATOM   6769 C C   . VAL E 5 553 ? 150.542 125.977 159.031 1.00 120.93 ? 15  VAL R C   1 
ATOM   6770 O O   . VAL E 5 553 ? 150.509 126.437 157.882 1.00 122.17 ? 15  VAL R O   1 
ATOM   6771 C CB  . VAL E 5 553 ? 152.310 126.959 160.578 1.00 123.44 ? 15  VAL R CB  1 
ATOM   6772 C CG1 . VAL E 5 553 ? 152.808 125.654 161.126 1.00 125.31 ? 15  VAL R CG1 1 
ATOM   6773 C CG2 . VAL E 5 553 ? 153.132 127.383 159.373 1.00 123.03 ? 15  VAL R CG2 1 
ATOM   6774 N N   . LEU E 5 554 ? 150.308 124.682 159.276 1.00 124.90 ? 16  LEU R N   1 
ATOM   6775 C CA  . LEU E 5 554 ? 149.962 123.807 158.160 1.00 129.69 ? 16  LEU R CA  1 
ATOM   6776 C C   . LEU E 5 554 ? 148.618 124.191 157.542 1.00 129.73 ? 16  LEU R C   1 
ATOM   6777 O O   . LEU E 5 554 ? 148.493 124.227 156.312 1.00 129.99 ? 16  LEU R O   1 
ATOM   6778 C CB  . LEU E 5 554 ? 149.985 122.335 158.586 1.00 130.72 ? 16  LEU R CB  1 
ATOM   6779 C CG  . LEU E 5 554 ? 148.894 121.650 159.411 1.00 131.41 ? 16  LEU R CG  1 
ATOM   6780 C CD1 . LEU E 5 554 ? 147.786 121.111 158.519 1.00 128.76 ? 16  LEU R CD1 1 
ATOM   6781 C CD2 . LEU E 5 554 ? 149.508 120.515 160.223 1.00 128.86 ? 16  LEU R CD2 1 
ATOM   6782 N N   . GLU E 5 555 ? 147.605 124.496 158.365 1.00 117.35 ? 17  GLU R N   1 
ATOM   6783 C CA  . GLU E 5 555 ? 146.317 124.916 157.811 1.00 112.22 ? 17  GLU R CA  1 
ATOM   6784 C C   . GLU E 5 555 ? 146.451 126.210 157.020 1.00 112.66 ? 17  GLU R C   1 
ATOM   6785 O O   . GLU E 5 555 ? 145.863 126.358 155.942 1.00 113.44 ? 17  GLU R O   1 
ATOM   6786 C CB  . GLU E 5 555 ? 145.274 125.082 158.916 1.00 112.04 ? 17  GLU R CB  1 
ATOM   6787 C CG  . GLU E 5 555 ? 145.016 123.843 159.746 1.00 115.14 ? 17  GLU R CG  1 
ATOM   6788 C CD  . GLU E 5 555 ? 144.299 124.161 161.043 1.00 117.24 ? 17  GLU R CD  1 
ATOM   6789 O OE1 . GLU E 5 555 ? 143.301 124.907 161.001 1.00 119.54 ? 17  GLU R OE1 1 
ATOM   6790 O OE2 . GLU E 5 555 ? 144.734 123.670 162.106 1.00 116.09 ? 17  GLU R OE2 1 
ATOM   6791 N N   . SER E 5 556 ? 147.217 127.163 157.545 1.00 117.87 ? 18  SER R N   1 
ATOM   6792 C CA  . SER E 5 556 ? 147.408 128.429 156.853 1.00 120.77 ? 18  SER R CA  1 
ATOM   6793 C C   . SER E 5 556 ? 148.102 128.217 155.517 1.00 117.77 ? 18  SER R C   1 
ATOM   6794 O O   . SER E 5 556 ? 147.693 128.782 154.496 1.00 120.36 ? 18  SER R O   1 
ATOM   6795 C CB  . SER E 5 556 ? 148.206 129.388 157.734 1.00 121.93 ? 18  SER R CB  1 
ATOM   6796 O OG  . SER E 5 556 ? 149.559 128.980 157.830 1.00 124.45 ? 18  SER R OG  1 
ATOM   6797 N N   . LEU E 5 557 ? 149.146 127.386 155.495 1.00 109.21 ? 19  LEU R N   1 
ATOM   6798 C CA  . LEU E 5 557 ? 149.860 127.180 154.242 1.00 109.31 ? 19  LEU R CA  1 
ATOM   6799 C C   . LEU E 5 557 ? 148.992 126.454 153.223 1.00 112.43 ? 19  LEU R C   1 
ATOM   6800 O O   . LEU E 5 557 ? 149.033 126.786 152.033 1.00 111.50 ? 19  LEU R O   1 
ATOM   6801 C CB  . LEU E 5 557 ? 151.179 126.437 154.477 1.00 112.83 ? 19  LEU R CB  1 
ATOM   6802 C CG  . LEU E 5 557 ? 151.255 125.018 155.041 1.00 116.31 ? 19  LEU R CG  1 
ATOM   6803 C CD1 . LEU E 5 557 ? 151.148 123.968 153.943 1.00 113.92 ? 19  LEU R CD1 1 
ATOM   6804 C CD2 . LEU E 5 557 ? 152.549 124.840 155.821 1.00 114.03 ? 19  LEU R CD2 1 
ATOM   6805 N N   . THR E 5 558 ? 148.193 125.466 153.655 1.00 112.07 ? 20  THR R N   1 
ATOM   6806 C CA  . THR E 5 558 ? 147.356 124.779 152.672 1.00 110.40 ? 20  THR R CA  1 
ATOM   6807 C C   . THR E 5 558 ? 146.259 125.700 152.158 1.00 108.60 ? 20  THR R C   1 
ATOM   6808 O O   . THR E 5 558 ? 145.927 125.667 150.969 1.00 110.33 ? 20  THR R O   1 
ATOM   6809 C CB  . THR E 5 558 ? 146.747 123.484 153.220 1.00 111.29 ? 20  THR R CB  1 
ATOM   6810 O OG1 . THR E 5 558 ? 145.729 123.034 152.318 1.00 109.71 ? 20  THR R OG1 1 
ATOM   6811 C CG2 . THR E 5 558 ? 146.094 123.697 154.547 1.00 111.99 ? 20  THR R CG2 1 
ATOM   6812 N N   . ILE E 5 559 ? 145.705 126.550 153.027 1.00 102.33 ? 21  ILE R N   1 
ATOM   6813 C CA  . ILE E 5 559 ? 144.741 127.545 152.566 1.00 104.36 ? 21  ILE R CA  1 
ATOM   6814 C C   . ILE E 5 559 ? 145.382 128.457 151.529 1.00 107.30 ? 21  ILE R C   1 
ATOM   6815 O O   . ILE E 5 559 ? 144.787 128.752 150.484 1.00 109.62 ? 21  ILE R O   1 
ATOM   6816 C CB  . ILE E 5 559 ? 144.189 128.347 153.759 1.00 103.44 ? 21  ILE R CB  1 
ATOM   6817 C CG1 . ILE E 5 559 ? 143.109 127.552 154.489 1.00 105.71 ? 21  ILE R CG1 1 
ATOM   6818 C CG2 . ILE E 5 559 ? 143.634 129.684 153.294 1.00 102.20 ? 21  ILE R CG2 1 
ATOM   6819 C CD1 . ILE E 5 559 ? 141.745 127.666 153.859 1.00 105.02 ? 21  ILE R CD1 1 
ATOM   6820 N N   . ILE E 5 560 ? 146.614 128.902 151.792 1.00 109.43 ? 22  ILE R N   1 
ATOM   6821 C CA  . ILE E 5 560 ? 147.279 129.830 150.881 1.00 106.46 ? 22  ILE R CA  1 
ATOM   6822 C C   . ILE E 5 560 ? 147.534 129.172 149.531 1.00 109.55 ? 22  ILE R C   1 
ATOM   6823 O O   . ILE E 5 560 ? 147.269 129.764 148.479 1.00 114.61 ? 22  ILE R O   1 
ATOM   6824 C CB  . ILE E 5 560 ? 148.581 130.363 151.504 1.00 106.46 ? 22  ILE R CB  1 
ATOM   6825 C CG1 . ILE E 5 560 ? 148.268 131.223 152.726 1.00 110.22 ? 22  ILE R CG1 1 
ATOM   6826 C CG2 . ILE E 5 560 ? 149.367 131.169 150.485 1.00 106.38 ? 22  ILE R CG2 1 
ATOM   6827 C CD1 . ILE E 5 560 ? 147.518 132.486 152.394 1.00 108.00 ? 22  ILE R CD1 1 
ATOM   6828 N N   . VAL E 5 561 ? 148.056 127.942 149.532 1.00 109.82 ? 23  VAL R N   1 
ATOM   6829 C CA  . VAL E 5 561 ? 148.371 127.309 148.253 1.00 110.28 ? 23  VAL R CA  1 
ATOM   6830 C C   . VAL E 5 561 ? 147.087 126.986 147.499 1.00 110.93 ? 23  VAL R C   1 
ATOM   6831 O O   . VAL E 5 561 ? 147.021 127.126 146.273 1.00 112.97 ? 23  VAL R O   1 
ATOM   6832 C CB  . VAL E 5 561 ? 149.253 126.057 148.433 1.00 112.68 ? 23  VAL R CB  1 
ATOM   6833 C CG1 . VAL E 5 561 ? 148.722 125.159 149.514 1.00 113.53 ? 23  VAL R CG1 1 
ATOM   6834 C CG2 . VAL E 5 561 ? 149.391 125.296 147.119 1.00 113.57 ? 23  VAL R CG2 1 
ATOM   6835 N N   . GLN E 5 562 ? 146.042 126.573 148.218 1.00 111.08 ? 24  GLN R N   1 
ATOM   6836 C CA  . GLN E 5 562 ? 144.754 126.298 147.593 1.00 110.55 ? 24  GLN R CA  1 
ATOM   6837 C C   . GLN E 5 562 ? 144.212 127.543 146.903 1.00 111.26 ? 24  GLN R C   1 
ATOM   6838 O O   . GLN E 5 562 ? 143.823 127.509 145.725 1.00 112.75 ? 24  GLN R O   1 
ATOM   6839 C CB  . GLN E 5 562 ? 143.788 125.810 148.671 1.00 109.60 ? 24  GLN R CB  1 
ATOM   6840 C CG  . GLN E 5 562 ? 144.107 124.487 149.310 1.00 113.22 ? 24  GLN R CG  1 
ATOM   6841 C CD  . GLN E 5 562 ? 144.135 123.370 148.282 1.00 120.12 ? 24  GLN R CD  1 
ATOM   6842 O OE1 . GLN E 5 562 ? 143.303 123.332 147.376 1.00 118.04 ? 24  GLN R OE1 1 
ATOM   6843 N NE2 . GLN E 5 562 ? 145.104 122.472 148.400 1.00 120.27 ? 24  GLN R NE2 1 
ATOM   6844 N N   . SER E 5 563 ? 144.203 128.664 147.624 1.00 103.78 ? 25  SER R N   1 
ATOM   6845 C CA  . SER E 5 563 ? 143.681 129.903 147.065 1.00 105.33 ? 25  SER R CA  1 
ATOM   6846 C C   . SER E 5 563 ? 144.537 130.397 145.906 1.00 110.79 ? 25  SER R C   1 
ATOM   6847 O O   . SER E 5 563 ? 144.006 130.901 144.912 1.00 111.09 ? 25  SER R O   1 
ATOM   6848 C CB  . SER E 5 563 ? 143.584 130.964 148.155 1.00 106.49 ? 25  SER R CB  1 
ATOM   6849 O OG  . SER E 5 563 ? 143.172 132.194 147.602 1.00 109.93 ? 25  SER R OG  1 
ATOM   6850 N N   . SER E 5 564 ? 145.862 130.275 146.014 1.00 121.02 ? 26  SER R N   1 
ATOM   6851 C CA  . SER E 5 564 ? 146.727 130.717 144.926 1.00 119.34 ? 26  SER R CA  1 
ATOM   6852 C C   . SER E 5 564 ? 146.546 129.846 143.691 1.00 115.86 ? 26  SER R C   1 
ATOM   6853 O O   . SER E 5 564 ? 146.610 130.341 142.560 1.00 116.25 ? 26  SER R O   1 
ATOM   6854 C CB  . SER E 5 564 ? 148.187 130.714 145.376 1.00 117.77 ? 26  SER R CB  1 
ATOM   6855 O OG  . SER E 5 564 ? 148.549 129.461 145.924 1.00 118.33 ? 26  SER R OG  1 
ATOM   6856 N N   . LEU E 5 565 ? 146.330 128.544 143.885 1.00 105.44 ? 27  LEU R N   1 
ATOM   6857 C CA  . LEU E 5 565 ? 146.058 127.666 142.756 1.00 105.11 ? 27  LEU R CA  1 
ATOM   6858 C C   . LEU E 5 565 ? 144.760 128.057 142.068 1.00 107.83 ? 27  LEU R C   1 
ATOM   6859 O O   . LEU E 5 565 ? 144.685 128.074 140.833 1.00 113.17 ? 27  LEU R O   1 
ATOM   6860 C CB  . LEU E 5 565 ? 146.007 126.212 143.222 1.00 108.25 ? 27  LEU R CB  1 
ATOM   6861 C CG  . LEU E 5 565 ? 145.553 125.187 142.183 1.00 109.60 ? 27  LEU R CG  1 
ATOM   6862 C CD1 . LEU E 5 565 ? 146.518 125.158 141.010 1.00 110.47 ? 27  LEU R CD1 1 
ATOM   6863 C CD2 . LEU E 5 565 ? 145.429 123.810 142.812 1.00 108.38 ? 27  LEU R CD2 1 
ATOM   6864 N N   . ILE E 5 566 ? 143.726 128.376 142.851 1.00 100.01 ? 28  ILE R N   1 
ATOM   6865 C CA  . ILE E 5 566 ? 142.490 128.874 142.250 1.00 102.01 ? 28  ILE R CA  1 
ATOM   6866 C C   . ILE E 5 566 ? 142.736 130.177 141.507 1.00 102.99 ? 28  ILE R C   1 
ATOM   6867 O O   . ILE E 5 566 ? 142.241 130.371 140.391 1.00 101.22 ? 28  ILE R O   1 
ATOM   6868 C CB  . ILE E 5 566 ? 141.385 129.019 143.310 1.00 99.61  ? 28  ILE R CB  1 
ATOM   6869 C CG1 . ILE E 5 566 ? 141.169 127.677 143.990 1.00 100.12 ? 28  ILE R CG1 1 
ATOM   6870 C CG2 . ILE E 5 566 ? 140.095 129.494 142.673 1.00 99.46  ? 28  ILE R CG2 1 
ATOM   6871 C CD1 . ILE E 5 566 ? 140.775 126.606 143.001 1.00 99.97  ? 28  ILE R CD1 1 
ATOM   6872 N N   . VAL E 5 567 ? 143.516 131.080 142.100 1.00 110.58 ? 29  VAL R N   1 
ATOM   6873 C CA  . VAL E 5 567 ? 143.825 132.339 141.431 1.00 113.88 ? 29  VAL R CA  1 
ATOM   6874 C C   . VAL E 5 567 ? 144.450 132.063 140.072 1.00 115.16 ? 29  VAL R C   1 
ATOM   6875 O O   . VAL E 5 567 ? 143.977 132.552 139.041 1.00 112.81 ? 29  VAL R O   1 
ATOM   6876 C CB  . VAL E 5 567 ? 144.741 133.208 142.310 1.00 111.73 ? 29  VAL R CB  1 
ATOM   6877 C CG1 . VAL E 5 567 ? 145.367 134.320 141.483 1.00 110.73 ? 29  VAL R CG1 1 
ATOM   6878 C CG2 . VAL E 5 567 ? 143.959 133.784 143.479 1.00 108.11 ? 29  VAL R CG2 1 
ATOM   6879 N N   . ALA E 5 568 ? 145.472 131.207 140.048 1.00 108.06 ? 30  ALA R N   1 
ATOM   6880 C CA  . ALA E 5 568 ? 146.176 130.922 138.804 1.00 102.26 ? 30  ALA R CA  1 
ATOM   6881 C C   . ALA E 5 568 ? 145.246 130.302 137.769 1.00 104.51 ? 30  ALA R C   1 
ATOM   6882 O O   . ALA E 5 568 ? 145.131 130.805 136.645 1.00 108.27 ? 30  ALA R O   1 
ATOM   6883 C CB  . ALA E 5 568 ? 147.366 130.002 139.078 1.00 102.91 ? 30  ALA R CB  1 
ATOM   6884 N N   . VAL E 5 569 ? 144.545 129.227 138.138 1.00 100.06 ? 31  VAL R N   1 
ATOM   6885 C CA  . VAL E 5 569 ? 143.786 128.482 137.139 1.00 99.02  ? 31  VAL R CA  1 
ATOM   6886 C C   . VAL E 5 569 ? 142.593 129.293 136.642 1.00 103.02 ? 31  VAL R C   1 
ATOM   6887 O O   . VAL E 5 569 ? 142.332 129.358 135.433 1.00 109.57 ? 31  VAL R O   1 
ATOM   6888 C CB  . VAL E 5 569 ? 143.366 127.103 137.687 1.00 98.46  ? 31  VAL R CB  1 
ATOM   6889 C CG1 . VAL E 5 569 ? 142.421 127.231 138.869 1.00 100.98 ? 31  VAL R CG1 1 
ATOM   6890 C CG2 . VAL E 5 569 ? 142.733 126.271 136.589 1.00 103.05 ? 31  VAL R CG2 1 
ATOM   6891 N N   . LEU E 5 570 ? 141.865 129.951 137.549 1.00 100.13 ? 32  LEU R N   1 
ATOM   6892 C CA  . LEU E 5 570 ? 140.680 130.683 137.128 1.00 100.46 ? 32  LEU R CA  1 
ATOM   6893 C C   . LEU E 5 570 ? 141.050 131.963 136.392 1.00 105.92 ? 32  LEU R C   1 
ATOM   6894 O O   . LEU E 5 570 ? 140.356 132.356 135.450 1.00 108.21 ? 32  LEU R O   1 
ATOM   6895 C CB  . LEU E 5 570 ? 139.790 130.984 138.330 1.00 103.63 ? 32  LEU R CB  1 
ATOM   6896 C CG  . LEU E 5 570 ? 138.607 130.031 138.493 1.00 102.29 ? 32  LEU R CG  1 
ATOM   6897 C CD1 . LEU E 5 570 ? 137.795 130.020 137.221 1.00 99.97  ? 32  LEU R CD1 1 
ATOM   6898 C CD2 . LEU E 5 570 ? 139.072 128.632 138.845 1.00 102.03 ? 32  LEU R CD2 1 
ATOM   6899 N N   . GLY E 5 571 ? 142.140 132.627 136.788 1.00 108.96 ? 33  GLY R N   1 
ATOM   6900 C CA  . GLY E 5 571 ? 142.598 133.771 136.024 1.00 107.61 ? 33  GLY R CA  1 
ATOM   6901 C C   . GLY E 5 571 ? 143.058 133.383 134.634 1.00 107.02 ? 33  GLY R C   1 
ATOM   6902 O O   . GLY E 5 571 ? 142.800 134.098 133.665 1.00 107.33 ? 33  GLY R O   1 
ATOM   6903 N N   . ARG E 5 572 ? 143.741 132.241 134.515 1.00 103.50 ? 34  ARG R N   1 
ATOM   6904 C CA  . ARG E 5 572 ? 144.143 131.764 133.198 1.00 100.34 ? 34  ARG R CA  1 
ATOM   6905 C C   . ARG E 5 572 ? 142.928 131.468 132.330 1.00 100.67 ? 34  ARG R C   1 
ATOM   6906 O O   . ARG E 5 572 ? 142.889 131.848 131.153 1.00 107.36 ? 34  ARG R O   1 
ATOM   6907 C CB  . ARG E 5 572 ? 145.026 130.526 133.347 1.00 103.33 ? 34  ARG R CB  1 
ATOM   6908 C CG  . ARG E 5 572 ? 144.956 129.552 132.189 1.00 107.00 ? 34  ARG R CG  1 
ATOM   6909 C CD  . ARG E 5 572 ? 146.342 129.055 131.817 1.00 108.46 ? 34  ARG R CD  1 
ATOM   6910 N NE  . ARG E 5 572 ? 147.045 128.508 132.971 1.00 109.90 ? 34  ARG R NE  1 
ATOM   6911 C CZ  . ARG E 5 572 ? 146.987 127.239 133.351 1.00 109.54 ? 34  ARG R CZ  1 
ATOM   6912 N NH1 . ARG E 5 572 ? 146.264 126.351 132.688 1.00 104.33 ? 34  ARG R NH1 1 
ATOM   6913 N NH2 . ARG E 5 572 ? 147.671 126.851 134.423 1.00 106.86 ? 34  ARG R NH2 1 
ATOM   6914 N N   . GLU E 5 573 ? 141.914 130.810 132.899 1.00 105.03 ? 35  GLU R N   1 
ATOM   6915 C CA  . GLU E 5 573 ? 140.705 130.525 132.132 1.00 108.64 ? 35  GLU R CA  1 
ATOM   6916 C C   . GLU E 5 573 ? 139.984 131.806 131.731 1.00 110.72 ? 35  GLU R C   1 
ATOM   6917 O O   . GLU E 5 573 ? 139.500 131.928 130.600 1.00 112.75 ? 35  GLU R O   1 
ATOM   6918 C CB  . GLU E 5 573 ? 139.772 129.617 132.930 1.00 110.49 ? 35  GLU R CB  1 
ATOM   6919 C CG  . GLU E 5 573 ? 138.502 129.238 132.186 1.00 113.08 ? 35  GLU R CG  1 
ATOM   6920 C CD  . GLU E 5 573 ? 138.719 128.116 131.189 1.00 114.89 ? 35  GLU R CD  1 
ATOM   6921 O OE1 . GLU E 5 573 ? 139.832 127.550 131.157 1.00 116.10 ? 35  GLU R OE1 1 
ATOM   6922 O OE2 . GLU E 5 573 ? 137.775 127.801 130.434 1.00 114.43 ? 35  GLU R OE2 1 
ATOM   6923 N N   . TRP E 5 574 ? 139.898 132.773 132.648 1.00 106.47 ? 36  TRP R N   1 
ATOM   6924 C CA  . TRP E 5 574 ? 139.226 134.031 132.345 1.00 106.99 ? 36  TRP R CA  1 
ATOM   6925 C C   . TRP E 5 574 ? 139.965 134.803 131.263 1.00 110.13 ? 36  TRP R C   1 
ATOM   6926 O O   . TRP E 5 574 ? 139.341 135.407 130.385 1.00 112.31 ? 36  TRP R O   1 
ATOM   6927 C CB  . TRP E 5 574 ? 139.099 134.870 133.615 1.00 105.72 ? 36  TRP R CB  1 
ATOM   6928 C CG  . TRP E 5 574 ? 137.975 135.851 133.580 1.00 105.55 ? 36  TRP R CG  1 
ATOM   6929 C CD1 . TRP E 5 574 ? 137.232 136.207 132.494 1.00 108.10 ? 36  TRP R CD1 1 
ATOM   6930 C CD2 . TRP E 5 574 ? 137.457 136.600 134.684 1.00 107.25 ? 36  TRP R CD2 1 
ATOM   6931 N NE1 . TRP E 5 574 ? 136.285 137.134 132.852 1.00 108.45 ? 36  TRP R NE1 1 
ATOM   6932 C CE2 . TRP E 5 574 ? 136.402 137.392 134.192 1.00 108.95 ? 36  TRP R CE2 1 
ATOM   6933 C CE3 . TRP E 5 574 ? 137.784 136.679 136.040 1.00 107.82 ? 36  TRP R CE3 1 
ATOM   6934 C CZ2 . TRP E 5 574 ? 135.672 138.253 135.008 1.00 109.25 ? 36  TRP R CZ2 1 
ATOM   6935 C CZ3 . TRP E 5 574 ? 137.058 137.533 136.848 1.00 108.01 ? 36  TRP R CZ3 1 
ATOM   6936 C CH2 . TRP E 5 574 ? 136.015 138.308 136.330 1.00 109.57 ? 36  TRP R CH2 1 
ATOM   6937 N N   . LEU E 5 575 ? 141.297 134.807 131.316 1.00 109.90 ? 37  LEU R N   1 
ATOM   6938 C CA  . LEU E 5 575 ? 142.078 135.475 130.283 1.00 109.57 ? 37  LEU R CA  1 
ATOM   6939 C C   . LEU E 5 575 ? 141.912 134.788 128.934 1.00 110.54 ? 37  LEU R C   1 
ATOM   6940 O O   . LEU E 5 575 ? 141.804 135.457 127.900 1.00 110.12 ? 37  LEU R O   1 
ATOM   6941 C CB  . LEU E 5 575 ? 143.551 135.515 130.688 1.00 106.00 ? 37  LEU R CB  1 
ATOM   6942 C CG  . LEU E 5 575 ? 144.137 136.898 130.971 1.00 106.93 ? 37  LEU R CG  1 
ATOM   6943 C CD1 . LEU E 5 575 ? 145.643 136.814 131.152 1.00 107.53 ? 37  LEU R CD1 1 
ATOM   6944 C CD2 . LEU E 5 575 ? 143.781 137.868 129.859 1.00 107.63 ? 37  LEU R CD2 1 
ATOM   6945 N N   . GLN E 5 576 ? 141.890 133.453 128.922 1.00 109.07 ? 38  GLN R N   1 
ATOM   6946 C CA  . GLN E 5 576 ? 141.805 132.733 127.657 1.00 109.24 ? 38  GLN R CA  1 
ATOM   6947 C C   . GLN E 5 576 ? 140.422 132.852 127.028 1.00 111.67 ? 38  GLN R C   1 
ATOM   6948 O O   . GLN E 5 576 ? 140.301 132.952 125.802 1.00 115.71 ? 38  GLN R O   1 
ATOM   6949 C CB  . GLN E 5 576 ? 142.175 131.265 127.865 1.00 110.89 ? 38  GLN R CB  1 
ATOM   6950 C CG  . GLN E 5 576 ? 143.663 131.026 128.046 1.00 109.63 ? 38  GLN R CG  1 
ATOM   6951 C CD  . GLN E 5 576 ? 144.017 129.553 128.061 1.00 113.71 ? 38  GLN R CD  1 
ATOM   6952 O OE1 . GLN E 5 576 ? 144.557 129.043 129.041 1.00 113.21 ? 38  GLN R OE1 1 
ATOM   6953 N NE2 . GLN E 5 576 ? 143.712 128.861 126.970 1.00 114.05 ? 38  GLN R NE2 1 
ATOM   6954 N N   . VAL E 5 577 ? 139.369 132.844 127.841 1.00 108.59 ? 39  VAL R N   1 
ATOM   6955 C CA  . VAL E 5 577 ? 138.009 132.771 127.317 1.00 111.79 ? 39  VAL R CA  1 
ATOM   6956 C C   . VAL E 5 577 ? 137.400 134.166 127.240 1.00 112.15 ? 39  VAL R C   1 
ATOM   6957 O O   . VAL E 5 577 ? 136.562 134.442 126.373 1.00 113.85 ? 39  VAL R O   1 
ATOM   6958 C CB  . VAL E 5 577 ? 137.148 131.826 128.178 1.00 110.85 ? 39  VAL R CB  1 
ATOM   6959 C CG1 . VAL E 5 577 ? 135.664 131.986 127.870 1.00 109.48 ? 39  VAL R CG1 1 
ATOM   6960 C CG2 . VAL E 5 577 ? 137.585 130.384 127.974 1.00 109.62 ? 39  VAL R CG2 1 
ATOM   6961 N N   . ARG E 5 578 ? 137.834 135.059 128.132 1.00 106.57 ? 40  ARG R N   1 
ATOM   6962 C CA  . ARG E 5 578 ? 137.265 136.397 128.300 1.00 106.13 ? 40  ARG R CA  1 
ATOM   6963 C C   . ARG E 5 578 ? 135.817 136.345 128.772 1.00 106.72 ? 40  ARG R C   1 
ATOM   6964 O O   . ARG E 5 578 ? 135.077 137.324 128.638 1.00 106.75 ? 40  ARG R O   1 
ATOM   6965 C CB  . ARG E 5 578 ? 137.382 137.234 127.020 1.00 106.13 ? 40  ARG R CB  1 
ATOM   6966 C CG  . ARG E 5 578 ? 137.571 138.720 127.268 1.00 107.12 ? 40  ARG R CG  1 
ATOM   6967 C CD  . ARG E 5 578 ? 138.755 139.258 126.492 1.00 106.48 ? 40  ARG R CD  1 
ATOM   6968 N NE  . ARG E 5 578 ? 139.996 138.595 126.870 1.00 103.33 ? 40  ARG R NE  1 
ATOM   6969 C CZ  . ARG E 5 578 ? 141.201 138.993 126.487 1.00 105.28 ? 40  ARG R CZ  1 
ATOM   6970 N NH1 . ARG E 5 578 ? 141.366 140.055 125.717 1.00 109.06 ? 40  ARG R NH1 1 
ATOM   6971 N NH2 . ARG E 5 578 ? 142.268 138.306 126.886 1.00 104.14 ? 40  ARG R NH2 1 
ATOM   6972 N N   . ARG E 5 579 ? 135.404 135.208 129.323 1.00 113.16 ? 41  ARG R N   1 
ATOM   6973 C CA  . ARG E 5 579 ? 134.093 135.056 129.933 1.00 111.91 ? 41  ARG R CA  1 
ATOM   6974 C C   . ARG E 5 579 ? 134.187 133.940 130.960 1.00 111.45 ? 41  ARG R C   1 
ATOM   6975 O O   . ARG E 5 579 ? 135.023 133.043 130.830 1.00 114.28 ? 41  ARG R O   1 
ATOM   6976 C CB  . ARG E 5 579 ? 133.013 134.746 128.891 1.00 112.73 ? 41  ARG R CB  1 
ATOM   6977 C CG  . ARG E 5 579 ? 131.602 134.621 129.459 1.00 115.50 ? 41  ARG R CG  1 
ATOM   6978 C CD  . ARG E 5 579 ? 130.584 134.265 128.383 1.00 119.11 ? 41  ARG R CD  1 
ATOM   6979 N NE  . ARG E 5 579 ? 130.825 132.943 127.818 1.00 119.69 ? 41  ARG R NE  1 
ATOM   6980 C CZ  . ARG E 5 579 ? 130.330 132.518 126.664 1.00 114.95 ? 41  ARG R CZ  1 
ATOM   6981 N NH1 . ARG E 5 579 ? 129.558 133.288 125.916 1.00 114.57 ? 41  ARG R NH1 1 
ATOM   6982 N NH2 . ARG E 5 579 ? 130.618 131.287 126.247 1.00 111.25 ? 41  ARG R NH2 1 
ATOM   6983 N N   . LEU E 5 580 ? 133.339 134.006 131.981 1.00 104.03 ? 42  LEU R N   1 
ATOM   6984 C CA  . LEU E 5 580 ? 133.339 133.006 133.036 1.00 104.99 ? 42  LEU R CA  1 
ATOM   6985 C C   . LEU E 5 580 ? 131.933 132.866 133.593 1.00 106.63 ? 42  LEU R C   1 
ATOM   6986 O O   . LEU E 5 580 ? 131.218 133.860 133.746 1.00 108.92 ? 42  LEU R O   1 
ATOM   6987 C CB  . LEU E 5 580 ? 134.313 133.382 134.157 1.00 103.21 ? 42  LEU R CB  1 
ATOM   6988 C CG  . LEU E 5 580 ? 135.693 132.729 134.098 1.00 102.15 ? 42  LEU R CG  1 
ATOM   6989 C CD1 . LEU E 5 580 ? 136.427 132.912 135.413 1.00 104.74 ? 42  LEU R CD1 1 
ATOM   6990 C CD2 . LEU E 5 580 ? 135.574 131.258 133.744 1.00 99.44  ? 42  LEU R CD2 1 
ATOM   6991 N N   . MET E 5 581 ? 131.540 131.631 133.889 1.00 105.63 ? 43  MET R N   1 
ATOM   6992 C CA  . MET E 5 581 ? 130.272 131.412 134.559 1.00 104.08 ? 43  MET R CA  1 
ATOM   6993 C C   . MET E 5 581 ? 130.323 132.039 135.951 1.00 100.14 ? 43  MET R C   1 
ATOM   6994 O O   . MET E 5 581 ? 131.385 132.086 136.578 1.00 104.04 ? 43  MET R O   1 
ATOM   6995 C CB  . MET E 5 581 ? 129.956 129.920 134.652 1.00 106.82 ? 43  MET R CB  1 
ATOM   6996 C CG  . MET E 5 581 ? 131.107 129.061 135.136 1.00 107.18 ? 43  MET R CG  1 
ATOM   6997 S SD  . MET E 5 581 ? 132.567 129.252 134.101 1.00 115.45 ? 43  MET R SD  1 
ATOM   6998 C CE  . MET E 5 581 ? 132.203 128.089 132.789 1.00 108.07 ? 43  MET R CE  1 
ATOM   6999 N N   . PRO E 5 582 ? 129.192 132.537 136.453 1.00 91.52  ? 44  PRO R N   1 
ATOM   7000 C CA  . PRO E 5 582 ? 129.230 133.324 137.697 1.00 99.88  ? 44  PRO R CA  1 
ATOM   7001 C C   . PRO E 5 582 ? 129.811 132.574 138.882 1.00 101.82 ? 44  PRO R C   1 
ATOM   7002 O O   . PRO E 5 582 ? 130.407 133.206 139.765 1.00 105.98 ? 44  PRO R O   1 
ATOM   7003 C CB  . PRO E 5 582 ? 127.757 133.689 137.921 1.00 99.69  ? 44  PRO R CB  1 
ATOM   7004 C CG  . PRO E 5 582 ? 127.124 133.577 136.571 1.00 98.71  ? 44  PRO R CG  1 
ATOM   7005 C CD  . PRO E 5 582 ? 127.834 132.455 135.890 1.00 92.84  ? 44  PRO R CD  1 
ATOM   7006 N N   . VAL E 5 583 ? 129.663 131.248 138.931 1.00 94.90  ? 45  VAL R N   1 
ATOM   7007 C CA  . VAL E 5 583 ? 130.299 130.486 140.001 1.00 90.96  ? 45  VAL R CA  1 
ATOM   7008 C C   . VAL E 5 583 ? 131.810 130.641 139.937 1.00 88.92  ? 45  VAL R C   1 
ATOM   7009 O O   . VAL E 5 583 ? 132.477 130.702 140.974 1.00 95.41  ? 45  VAL R O   1 
ATOM   7010 C CB  . VAL E 5 583 ? 129.870 129.004 139.955 1.00 94.05  ? 45  VAL R CB  1 
ATOM   7011 C CG1 . VAL E 5 583 ? 130.626 128.235 138.886 1.00 102.85 ? 45  VAL R CG1 1 
ATOM   7012 C CG2 . VAL E 5 583 ? 130.067 128.360 141.315 1.00 88.31  ? 45  VAL R CG2 1 
ATOM   7013 N N   . ASP E 5 584 ? 132.372 130.748 138.733 1.00 98.02  ? 46  ASP R N   1 
ATOM   7014 C CA  . ASP E 5 584 ? 133.818 130.880 138.612 1.00 100.71 ? 46  ASP R CA  1 
ATOM   7015 C C   . ASP E 5 584 ? 134.294 132.249 139.080 1.00 105.44 ? 46  ASP R C   1 
ATOM   7016 O O   . ASP E 5 584 ? 135.329 132.356 139.747 1.00 104.51 ? 46  ASP R O   1 
ATOM   7017 C CB  . ASP E 5 584 ? 134.245 130.622 137.172 1.00 107.51 ? 46  ASP R CB  1 
ATOM   7018 C CG  . ASP E 5 584 ? 134.529 129.163 136.910 1.00 112.23 ? 46  ASP R CG  1 
ATOM   7019 O OD1 . ASP E 5 584 ? 134.235 128.332 137.795 1.00 107.10 ? 46  ASP R OD1 1 
ATOM   7020 O OD2 . ASP E 5 584 ? 135.060 128.851 135.827 1.00 117.62 ? 46  ASP R OD2 1 
ATOM   7021 N N   . MET E 5 585 ? 133.561 133.309 138.736 1.00 106.42 ? 47  MET R N   1 
ATOM   7022 C CA  . MET E 5 585 ? 133.925 134.638 139.218 1.00 106.68 ? 47  MET R CA  1 
ATOM   7023 C C   . MET E 5 585 ? 133.787 134.730 140.733 1.00 110.87 ? 47  MET R C   1 
ATOM   7024 O O   . MET E 5 585 ? 134.636 135.329 141.407 1.00 113.58 ? 47  MET R O   1 
ATOM   7025 C CB  . MET E 5 585 ? 133.069 135.698 138.528 1.00 103.79 ? 47  MET R CB  1 
ATOM   7026 C CG  . MET E 5 585 ? 133.187 135.689 137.014 1.00 105.03 ? 47  MET R CG  1 
ATOM   7027 S SD  . MET E 5 585 ? 132.192 136.960 136.215 1.00 108.56 ? 47  MET R SD  1 
ATOM   7028 C CE  . MET E 5 585 ? 130.988 137.297 137.492 1.00 105.25 ? 47  MET R CE  1 
ATOM   7029 N N   . ILE E 5 586 ? 132.725 134.142 141.286 1.00 93.84  ? 48  ILE R N   1 
ATOM   7030 C CA  . ILE E 5 586 ? 132.576 134.114 142.737 1.00 90.26  ? 48  ILE R CA  1 
ATOM   7031 C C   . ILE E 5 586 ? 133.731 133.355 143.373 1.00 88.48  ? 48  ILE R C   1 
ATOM   7032 O O   . ILE E 5 586 ? 134.298 133.789 144.382 1.00 93.51  ? 48  ILE R O   1 
ATOM   7033 C CB  . ILE E 5 586 ? 131.219 133.507 143.128 1.00 84.14  ? 48  ILE R CB  1 
ATOM   7034 C CG1 . ILE E 5 586 ? 130.126 134.561 143.021 1.00 83.51  ? 48  ILE R CG1 1 
ATOM   7035 C CG2 . ILE E 5 586 ? 131.278 132.981 144.538 1.00 87.19  ? 48  ILE R CG2 1 
ATOM   7036 C CD1 . ILE E 5 586 ? 130.283 135.669 144.021 1.00 86.34  ? 48  ILE R CD1 1 
ATOM   7037 N N   . LEU E 5 587 ? 134.103 132.215 142.790 1.00 88.65  ? 49  LEU R N   1 
ATOM   7038 C CA  . LEU E 5 587 ? 135.195 131.424 143.340 1.00 83.83  ? 49  LEU R CA  1 
ATOM   7039 C C   . LEU E 5 587 ? 136.516 132.172 143.263 1.00 89.49  ? 49  LEU R C   1 
ATOM   7040 O O   . LEU E 5 587 ? 137.333 132.079 144.179 1.00 96.80  ? 49  LEU R O   1 
ATOM   7041 C CB  . LEU E 5 587 ? 135.293 130.084 142.615 1.00 91.94  ? 49  LEU R CB  1 
ATOM   7042 C CG  . LEU E 5 587 ? 134.093 129.159 142.804 1.00 97.26  ? 49  LEU R CG  1 
ATOM   7043 C CD1 . LEU E 5 587 ? 134.233 127.929 141.926 1.00 96.08  ? 49  LEU R CD1 1 
ATOM   7044 C CD2 . LEU E 5 587 ? 133.945 128.765 144.263 1.00 97.01  ? 49  LEU R CD2 1 
ATOM   7045 N N   . ILE E 5 588 ? 136.748 132.922 142.185 1.00 88.34  ? 50  ILE R N   1 
ATOM   7046 C CA  . ILE E 5 588 ? 138.010 133.650 142.070 1.00 93.28  ? 50  ILE R CA  1 
ATOM   7047 C C   . ILE E 5 588 ? 138.066 134.801 143.071 1.00 93.25  ? 50  ILE R C   1 
ATOM   7048 O O   . ILE E 5 588 ? 139.093 135.018 143.734 1.00 93.92  ? 50  ILE R O   1 
ATOM   7049 C CB  . ILE E 5 588 ? 138.248 134.110 140.616 1.00 96.79  ? 50  ILE R CB  1 
ATOM   7050 C CG1 . ILE E 5 588 ? 139.738 134.318 140.379 1.00 98.79  ? 50  ILE R CG1 1 
ATOM   7051 C CG2 . ILE E 5 588 ? 137.485 135.375 140.262 1.00 98.67  ? 50  ILE R CG2 1 
ATOM   7052 C CD1 . ILE E 5 588 ? 140.567 133.205 140.918 1.00 97.86  ? 50  ILE R CD1 1 
ATOM   7053 N N   . SER E 5 589 ? 136.962 135.539 143.222 1.00 84.48  ? 51  SER R N   1 
ATOM   7054 C CA  . SER E 5 589 ? 136.940 136.613 144.206 1.00 86.23  ? 51  SER R CA  1 
ATOM   7055 C C   . SER E 5 589 ? 137.124 136.061 145.612 1.00 83.52  ? 51  SER R C   1 
ATOM   7056 O O   . SER E 5 589 ? 137.902 136.601 146.409 1.00 92.26  ? 51  SER R O   1 
ATOM   7057 C CB  . SER E 5 589 ? 135.632 137.394 144.095 1.00 85.38  ? 51  SER R CB  1 
ATOM   7058 O OG  . SER E 5 589 ? 134.518 136.539 144.274 1.00 88.13  ? 51  SER R OG  1 
ATOM   7059 N N   . LEU E 5 590 ? 136.442 134.960 145.923 1.00 78.12  ? 52  LEU R N   1 
ATOM   7060 C CA  . LEU E 5 590 ? 136.559 134.376 147.249 1.00 77.73  ? 52  LEU R CA  1 
ATOM   7061 C C   . LEU E 5 590 ? 137.926 133.746 147.458 1.00 75.93  ? 52  LEU R C   1 
ATOM   7062 O O   . LEU E 5 590 ? 138.416 133.705 148.587 1.00 87.55  ? 52  LEU R O   1 
ATOM   7063 C CB  . LEU E 5 590 ? 135.441 133.359 147.461 1.00 80.06  ? 52  LEU R CB  1 
ATOM   7064 C CG  . LEU E 5 590 ? 135.323 132.756 148.852 1.00 74.30  ? 52  LEU R CG  1 
ATOM   7065 C CD1 . LEU E 5 590 ? 135.409 133.857 149.876 1.00 83.86  ? 52  LEU R CD1 1 
ATOM   7066 C CD2 . LEU E 5 590 ? 133.994 132.063 148.967 1.00 75.84  ? 52  LEU R CD2 1 
ATOM   7067 N N   . GLY E 5 591 ? 138.565 133.271 146.389 1.00 75.17  ? 53  GLY R N   1 
ATOM   7068 C CA  . GLY E 5 591 ? 139.924 132.776 146.513 1.00 79.03  ? 53  GLY R CA  1 
ATOM   7069 C C   . GLY E 5 591 ? 140.907 133.871 146.878 1.00 86.26  ? 53  GLY R C   1 
ATOM   7070 O O   . GLY E 5 591 ? 141.734 133.700 147.779 1.00 93.08  ? 53  GLY R O   1 
ATOM   7071 N N   . ILE E 5 592 ? 140.832 135.012 146.188 1.00 87.47  ? 54  ILE R N   1 
ATOM   7072 C CA  . ILE E 5 592 ? 141.735 136.105 146.547 1.00 85.56  ? 54  ILE R CA  1 
ATOM   7073 C C   . ILE E 5 592 ? 141.425 136.600 147.956 1.00 84.76  ? 54  ILE R C   1 
ATOM   7074 O O   . ILE E 5 592 ? 142.338 136.930 148.731 1.00 88.71  ? 54  ILE R O   1 
ATOM   7075 C CB  . ILE E 5 592 ? 141.689 137.243 145.504 1.00 84.76  ? 54  ILE R CB  1 
ATOM   7076 C CG1 . ILE E 5 592 ? 140.469 138.146 145.691 1.00 82.49  ? 54  ILE R CG1 1 
ATOM   7077 C CG2 . ILE E 5 592 ? 141.739 136.684 144.092 1.00 90.16  ? 54  ILE R CG2 1 
ATOM   7078 C CD1 . ILE E 5 592 ? 140.327 139.208 144.626 1.00 86.43  ? 54  ILE R CD1 1 
ATOM   7079 N N   . SER E 5 593 ? 140.141 136.615 148.329 1.00 85.06  ? 55  SER R N   1 
ATOM   7080 C CA  . SER E 5 593 ? 139.767 137.027 149.677 1.00 86.77  ? 55  SER R CA  1 
ATOM   7081 C C   . SER E 5 593 ? 140.341 136.080 150.722 1.00 86.97  ? 55  SER R C   1 
ATOM   7082 O O   . SER E 5 593 ? 140.881 136.521 151.738 1.00 93.64  ? 55  SER R O   1 
ATOM   7083 C CB  . SER E 5 593 ? 138.249 137.107 149.796 1.00 85.28  ? 55  SER R CB  1 
ATOM   7084 O OG  . SER E 5 593 ? 137.738 138.139 148.975 1.00 94.24  ? 55  SER R OG  1 
ATOM   7085 N N   . ARG E 5 594 ? 140.235 134.772 150.487 1.00 84.34  ? 56  ARG R N   1 
ATOM   7086 C CA  . ARG E 5 594 ? 140.762 133.798 151.436 1.00 85.61  ? 56  ARG R CA  1 
ATOM   7087 C C   . ARG E 5 594 ? 142.276 133.889 151.540 1.00 86.96  ? 56  ARG R C   1 
ATOM   7088 O O   . ARG E 5 594 ? 142.829 133.815 152.643 1.00 92.43  ? 56  ARG R O   1 
ATOM   7089 C CB  . ARG E 5 594 ? 140.336 132.387 151.035 1.00 86.55  ? 56  ARG R CB  1 
ATOM   7090 C CG  . ARG E 5 594 ? 138.867 132.079 151.296 1.00 86.69  ? 56  ARG R CG  1 
ATOM   7091 C CD  . ARG E 5 594 ? 138.569 132.021 152.784 1.00 86.01  ? 56  ARG R CD  1 
ATOM   7092 N NE  . ARG E 5 594 ? 137.138 132.079 153.058 1.00 88.74  ? 56  ARG R NE  1 
ATOM   7093 C CZ  . ARG E 5 594 ? 136.292 131.077 152.866 1.00 85.29  ? 56  ARG R CZ  1 
ATOM   7094 N NH1 . ARG E 5 594 ? 136.697 129.907 152.399 1.00 90.21  ? 56  ARG R NH1 1 
ATOM   7095 N NH2 . ARG E 5 594 ? 135.005 131.252 153.150 1.00 82.91  ? 56  ARG R NH2 1 
ATOM   7096 N N   . PHE E 5 595 ? 142.965 134.059 150.408 1.00 90.73  ? 57  PHE R N   1 
ATOM   7097 C CA  . PHE E 5 595 ? 144.420 134.182 150.442 1.00 94.67  ? 57  PHE R CA  1 
ATOM   7098 C C   . PHE E 5 595 ? 144.838 135.381 151.279 1.00 96.09  ? 57  PHE R C   1 
ATOM   7099 O O   . PHE E 5 595 ? 145.660 135.265 152.200 1.00 97.17  ? 57  PHE R O   1 
ATOM   7100 C CB  . PHE E 5 595 ? 144.956 134.273 149.004 1.00 91.05  ? 57  PHE R CB  1 
ATOM   7101 C CG  . PHE E 5 595 ? 146.278 134.988 148.857 1.00 97.92  ? 57  PHE R CG  1 
ATOM   7102 C CD1 . PHE E 5 595 ? 146.339 136.367 148.770 1.00 98.12  ? 57  PHE R CD1 1 
ATOM   7103 C CD2 . PHE E 5 595 ? 147.454 134.267 148.711 1.00 100.73 ? 57  PHE R CD2 1 
ATOM   7104 C CE1 . PHE E 5 595 ? 147.543 137.018 148.613 1.00 98.04  ? 57  PHE R CE1 1 
ATOM   7105 C CE2 . PHE E 5 595 ? 148.666 134.914 148.549 1.00 102.22 ? 57  PHE R CE2 1 
ATOM   7106 C CZ  . PHE E 5 595 ? 148.708 136.291 148.498 1.00 99.59  ? 57  PHE R CZ  1 
ATOM   7107 N N   . CYS E 5 596 ? 144.251 136.542 150.994 1.00 102.34 ? 58  CYS R N   1 
ATOM   7108 C CA  . CYS E 5 596 ? 144.647 137.752 151.701 1.00 101.20 ? 58  CYS R CA  1 
ATOM   7109 C C   . CYS E 5 596 ? 144.239 137.698 153.171 1.00 99.48  ? 58  CYS R C   1 
ATOM   7110 O O   . CYS E 5 596 ? 144.996 138.135 154.048 1.00 104.18 ? 58  CYS R O   1 
ATOM   7111 C CB  . CYS E 5 596 ? 144.059 138.958 150.984 1.00 105.18 ? 58  CYS R CB  1 
ATOM   7112 S SG  . CYS E 5 596 ? 145.060 139.557 149.599 1.00 119.53 ? 58  CYS R SG  1 
ATOM   7113 N N   . LEU E 5 597 ? 143.059 137.142 153.460 1.00 91.38  ? 59  LEU R N   1 
ATOM   7114 C CA  . LEU E 5 597 ? 142.610 137.009 154.839 1.00 91.97  ? 59  LEU R CA  1 
ATOM   7115 C C   . LEU E 5 597 ? 143.523 136.085 155.627 1.00 93.33  ? 59  LEU R C   1 
ATOM   7116 O O   . LEU E 5 597 ? 143.829 136.356 156.790 1.00 97.59  ? 59  LEU R O   1 
ATOM   7117 C CB  . LEU E 5 597 ? 141.177 136.484 154.875 1.00 93.65  ? 59  LEU R CB  1 
ATOM   7118 C CG  . LEU E 5 597 ? 140.527 136.350 156.249 1.00 89.96  ? 59  LEU R CG  1 
ATOM   7119 C CD1 . LEU E 5 597 ? 140.320 137.724 156.868 1.00 91.83  ? 59  LEU R CD1 1 
ATOM   7120 C CD2 . LEU E 5 597 ? 139.215 135.590 156.134 1.00 92.23  ? 59  LEU R CD2 1 
ATOM   7121 N N   . GLN E 5 598 ? 143.960 134.980 155.019 1.00 96.91  ? 60  GLN R N   1 
ATOM   7122 C CA  . GLN E 5 598 ? 144.843 134.065 155.731 1.00 95.94  ? 60  GLN R CA  1 
ATOM   7123 C C   . GLN E 5 598 ? 146.207 134.694 155.975 1.00 103.63 ? 60  GLN R C   1 
ATOM   7124 O O   . GLN E 5 598 ? 146.795 134.511 157.049 1.00 106.69 ? 60  GLN R O   1 
ATOM   7125 C CB  . GLN E 5 598 ? 144.990 132.756 154.961 1.00 95.17  ? 60  GLN R CB  1 
ATOM   7126 C CG  . GLN E 5 598 ? 145.433 131.596 155.834 1.00 100.35 ? 60  GLN R CG  1 
ATOM   7127 C CD  . GLN E 5 598 ? 144.352 131.158 156.793 1.00 102.08 ? 60  GLN R CD  1 
ATOM   7128 O OE1 . GLN E 5 598 ? 143.170 131.415 156.566 1.00 103.87 ? 60  GLN R OE1 1 
ATOM   7129 N NE2 . GLN E 5 598 ? 144.747 130.498 157.876 1.00 101.49 ? 60  GLN R NE2 1 
ATOM   7130 N N   . TRP E 5 599 ? 146.731 135.434 154.994 1.00 106.30 ? 61  TRP R N   1 
ATOM   7131 C CA  . TRP E 5 599 ? 148.001 136.120 155.217 1.00 102.53 ? 61  TRP R CA  1 
ATOM   7132 C C   . TRP E 5 599 ? 147.881 137.136 156.346 1.00 101.08 ? 61  TRP R C   1 
ATOM   7133 O O   . TRP E 5 599 ? 148.749 137.207 157.231 1.00 101.36 ? 61  TRP R O   1 
ATOM   7134 C CB  . TRP E 5 599 ? 148.473 136.798 153.933 1.00 99.37  ? 61  TRP R CB  1 
ATOM   7135 C CG  . TRP E 5 599 ? 149.383 135.939 153.126 1.00 99.49  ? 61  TRP R CG  1 
ATOM   7136 C CD1 . TRP E 5 599 ? 149.131 135.411 151.898 1.00 101.75 ? 61  TRP R CD1 1 
ATOM   7137 C CD2 . TRP E 5 599 ? 150.693 135.497 153.494 1.00 100.90 ? 61  TRP R CD2 1 
ATOM   7138 N NE1 . TRP E 5 599 ? 150.203 134.665 151.475 1.00 102.34 ? 61  TRP R NE1 1 
ATOM   7139 C CE2 . TRP E 5 599 ? 151.176 134.703 152.437 1.00 98.68  ? 61  TRP R CE2 1 
ATOM   7140 C CE3 . TRP E 5 599 ? 151.505 135.698 154.612 1.00 106.07 ? 61  TRP R CE3 1 
ATOM   7141 C CZ2 . TRP E 5 599 ? 152.434 134.110 152.465 1.00 99.93  ? 61  TRP R CZ2 1 
ATOM   7142 C CZ3 . TRP E 5 599 ? 152.753 135.108 154.639 1.00 104.27 ? 61  TRP R CZ3 1 
ATOM   7143 C CH2 . TRP E 5 599 ? 153.205 134.323 153.573 1.00 101.95 ? 61  TRP R CH2 1 
ATOM   7144 N N   . ALA E 5 600 ? 146.799 137.917 156.343 1.00 106.21 ? 62  ALA R N   1 
ATOM   7145 C CA  . ALA E 5 600 ? 146.589 138.892 157.404 1.00 107.58 ? 62  ALA R CA  1 
ATOM   7146 C C   . ALA E 5 600 ? 146.442 138.209 158.755 1.00 106.43 ? 62  ALA R C   1 
ATOM   7147 O O   . ALA E 5 600 ? 146.976 138.688 159.760 1.00 112.18 ? 62  ALA R O   1 
ATOM   7148 C CB  . ALA E 5 600 ? 145.360 139.747 157.096 1.00 107.35 ? 62  ALA R CB  1 
ATOM   7149 N N   . SER E 5 601 ? 145.723 137.087 158.801 1.00 91.02  ? 63  SER R N   1 
ATOM   7150 C CA  . SER E 5 601 ? 145.546 136.377 160.060 1.00 92.78  ? 63  SER R CA  1 
ATOM   7151 C C   . SER E 5 601 ? 146.866 135.844 160.586 1.00 97.59  ? 63  SER R C   1 
ATOM   7152 O O   . SER E 5 601 ? 147.138 135.926 161.788 1.00 106.19 ? 63  SER R O   1 
ATOM   7153 C CB  . SER E 5 601 ? 144.556 135.234 159.887 1.00 98.49  ? 63  SER R CB  1 
ATOM   7154 O OG  . SER E 5 601 ? 144.190 134.715 161.153 1.00 104.50 ? 63  SER R OG  1 
ATOM   7155 N N   . MET E 5 602 ? 147.692 135.275 159.708 1.00 105.29 ? 64  MET R N   1 
ATOM   7156 C CA  . MET E 5 602 ? 148.990 134.780 160.148 1.00 110.52 ? 64  MET R CA  1 
ATOM   7157 C C   . MET E 5 602 ? 149.840 135.911 160.707 1.00 115.93 ? 64  MET R C   1 
ATOM   7158 O O   . MET E 5 602 ? 150.422 135.789 161.793 1.00 115.60 ? 64  MET R O   1 
ATOM   7159 C CB  . MET E 5 602 ? 149.711 134.080 158.997 1.00 106.30 ? 64  MET R CB  1 
ATOM   7160 C CG  . MET E 5 602 ? 149.608 132.569 159.041 1.00 112.69 ? 64  MET R CG  1 
ATOM   7161 S SD  . MET E 5 602 ? 150.803 131.764 157.962 1.00 122.58 ? 64  MET R SD  1 
ATOM   7162 C CE  . MET E 5 602 ? 150.828 132.905 156.588 1.00 111.83 ? 64  MET R CE  1 
ATOM   7163 N N   . LEU E 5 603 ? 149.899 137.037 159.990 1.00 118.34 ? 65  LEU R N   1 
ATOM   7164 C CA  . LEU E 5 603 ? 150.693 138.164 160.468 1.00 116.72 ? 65  LEU R CA  1 
ATOM   7165 C C   . LEU E 5 603 ? 150.177 138.664 161.813 1.00 115.88 ? 65  LEU R C   1 
ATOM   7166 O O   . LEU E 5 603 ? 150.957 138.891 162.748 1.00 121.24 ? 65  LEU R O   1 
ATOM   7167 C CB  . LEU E 5 603 ? 150.682 139.288 159.433 1.00 117.04 ? 65  LEU R CB  1 
ATOM   7168 C CG  . LEU E 5 603 ? 151.898 139.365 158.508 1.00 118.91 ? 65  LEU R CG  1 
ATOM   7169 C CD1 . LEU E 5 603 ? 151.839 140.618 157.649 1.00 118.17 ? 65  LEU R CD1 1 
ATOM   7170 C CD2 . LEU E 5 603 ? 153.188 139.323 159.312 1.00 118.72 ? 65  LEU R CD2 1 
ATOM   7171 N N   . ASN E 5 604 ? 148.857 138.813 161.935 1.00 105.58 ? 66  ASN R N   1 
ATOM   7172 C CA  . ASN E 5 604 ? 148.269 139.353 163.154 1.00 108.60 ? 66  ASN R CA  1 
ATOM   7173 C C   . ASN E 5 604 ? 148.505 138.427 164.338 1.00 105.90 ? 66  ASN R C   1 
ATOM   7174 O O   . ASN E 5 604 ? 148.906 138.872 165.419 1.00 109.93 ? 66  ASN R O   1 
ATOM   7175 C CB  . ASN E 5 604 ? 146.774 139.589 162.943 1.00 107.01 ? 66  ASN R CB  1 
ATOM   7176 C CG  . ASN E 5 604 ? 146.152 140.410 164.049 1.00 110.51 ? 66  ASN R CG  1 
ATOM   7177 O OD1 . ASN E 5 604 ? 146.804 141.262 164.648 1.00 111.23 ? 66  ASN R OD1 1 
ATOM   7178 N ND2 . ASN E 5 604 ? 144.878 140.156 164.328 1.00 113.14 ? 66  ASN R ND2 1 
ATOM   7179 N N   . ASN E 5 605 ? 148.258 137.129 164.153 1.00 100.32 ? 67  ASN R N   1 
ATOM   7180 C CA  . ASN E 5 605 ? 148.435 136.184 165.247 1.00 103.78 ? 67  ASN R CA  1 
ATOM   7181 C C   . ASN E 5 605 ? 149.894 136.088 165.662 1.00 109.69 ? 67  ASN R C   1 
ATOM   7182 O O   . ASN E 5 605 ? 150.198 136.021 166.860 1.00 116.99 ? 67  ASN R O   1 
ATOM   7183 C CB  . ASN E 5 605 ? 147.896 134.812 164.851 1.00 110.14 ? 67  ASN R CB  1 
ATOM   7184 C CG  . ASN E 5 605 ? 146.384 134.757 164.862 1.00 111.85 ? 67  ASN R CG  1 
ATOM   7185 O OD1 . ASN E 5 605 ? 145.749 135.084 165.863 1.00 110.26 ? 67  ASN R OD1 1 
ATOM   7186 N ND2 . ASN E 5 605 ? 145.798 134.340 163.746 1.00 111.99 ? 67  ASN R ND2 1 
ATOM   7187 N N   . PHE E 5 606 ? 150.816 136.075 164.695 1.00 118.14 ? 68  PHE R N   1 
ATOM   7188 C CA  . PHE E 5 606 ? 152.228 136.014 165.047 1.00 124.33 ? 68  PHE R CA  1 
ATOM   7189 C C   . PHE E 5 606 ? 152.655 137.256 165.817 1.00 124.94 ? 68  PHE R C   1 
ATOM   7190 O O   . PHE E 5 606 ? 153.342 137.153 166.842 1.00 122.83 ? 68  PHE R O   1 
ATOM   7191 C CB  . PHE E 5 606 ? 153.074 135.832 163.788 1.00 121.40 ? 68  PHE R CB  1 
ATOM   7192 C CG  . PHE E 5 606 ? 153.221 134.400 163.364 1.00 121.73 ? 68  PHE R CG  1 
ATOM   7193 C CD1 . PHE E 5 606 ? 152.773 133.376 164.180 1.00 120.29 ? 68  PHE R CD1 1 
ATOM   7194 C CD2 . PHE E 5 606 ? 153.807 134.077 162.152 1.00 124.38 ? 68  PHE R CD2 1 
ATOM   7195 C CE1 . PHE E 5 606 ? 152.904 132.057 163.797 1.00 120.72 ? 68  PHE R CE1 1 
ATOM   7196 C CE2 . PHE E 5 606 ? 153.942 132.758 161.763 1.00 125.98 ? 68  PHE R CE2 1 
ATOM   7197 C CZ  . PHE E 5 606 ? 153.490 131.747 162.586 1.00 123.45 ? 68  PHE R CZ  1 
ATOM   7198 N N   . CYS E 5 607 ? 152.234 138.439 165.359 1.00 129.62 ? 69  CYS R N   1 
ATOM   7199 C CA  . CYS E 5 607 ? 152.585 139.666 166.066 1.00 129.62 ? 69  CYS R CA  1 
ATOM   7200 C C   . CYS E 5 607 ? 151.997 139.680 167.471 1.00 129.09 ? 69  CYS R C   1 
ATOM   7201 O O   . CYS E 5 607 ? 152.657 140.111 168.424 1.00 131.46 ? 69  CYS R O   1 
ATOM   7202 C CB  . CYS E 5 607 ? 152.115 140.885 165.271 1.00 130.52 ? 69  CYS R CB  1 
ATOM   7203 S SG  . CYS E 5 607 ? 151.937 142.395 166.255 1.00 144.34 ? 69  CYS R SG  1 
ATOM   7204 N N   . SER E 5 608 ? 150.757 139.211 167.623 1.00 112.90 ? 70  SER R N   1 
ATOM   7205 C CA  . SER E 5 608 ? 150.112 139.244 168.931 1.00 113.36 ? 70  SER R CA  1 
ATOM   7206 C C   . SER E 5 608 ? 150.770 138.271 169.901 1.00 113.45 ? 70  SER R C   1 
ATOM   7207 O O   . SER E 5 608 ? 151.080 138.635 171.041 1.00 113.04 ? 70  SER R O   1 
ATOM   7208 C CB  . SER E 5 608 ? 148.623 138.934 168.790 1.00 117.44 ? 70  SER R CB  1 
ATOM   7209 O OG  . SER E 5 608 ? 148.011 138.822 170.062 1.00 119.52 ? 70  SER R OG  1 
ATOM   7210 N N   . TYR E 5 609 ? 150.990 137.027 169.473 1.00 119.65 ? 71  TYR R N   1 
ATOM   7211 C CA  . TYR E 5 609 ? 151.516 136.025 170.396 1.00 120.92 ? 71  TYR R CA  1 
ATOM   7212 C C   . TYR E 5 609 ? 152.991 136.257 170.689 1.00 121.77 ? 71  TYR R C   1 
ATOM   7213 O O   . TYR E 5 609 ? 153.465 135.967 171.794 1.00 123.94 ? 71  TYR R O   1 
ATOM   7214 C CB  . TYR E 5 609 ? 151.295 134.616 169.847 1.00 123.12 ? 71  TYR R CB  1 
ATOM   7215 C CG  . TYR E 5 609 ? 151.538 133.539 170.883 1.00 125.96 ? 71  TYR R CG  1 
ATOM   7216 C CD1 . TYR E 5 609 ? 152.803 132.996 171.067 1.00 124.47 ? 71  TYR R CD1 1 
ATOM   7217 C CD2 . TYR E 5 609 ? 150.505 133.081 171.691 1.00 127.17 ? 71  TYR R CD2 1 
ATOM   7218 C CE1 . TYR E 5 609 ? 153.031 132.020 172.016 1.00 123.90 ? 71  TYR R CE1 1 
ATOM   7219 C CE2 . TYR E 5 609 ? 150.724 132.105 172.644 1.00 126.83 ? 71  TYR R CE2 1 
ATOM   7220 C CZ  . TYR E 5 609 ? 151.988 131.578 172.802 1.00 124.98 ? 71  TYR R CZ  1 
ATOM   7221 O OH  . TYR E 5 609 ? 152.210 130.605 173.748 1.00 123.77 ? 71  TYR R OH  1 
ATOM   7222 N N   . PHE E 5 610 ? 153.743 136.765 169.713 1.00 123.62 ? 72  PHE R N   1 
ATOM   7223 C CA  . PHE E 5 610 ? 155.157 137.013 169.951 1.00 125.92 ? 72  PHE R CA  1 
ATOM   7224 C C   . PHE E 5 610 ? 155.423 138.386 170.549 1.00 126.94 ? 72  PHE R C   1 
ATOM   7225 O O   . PHE E 5 610 ? 156.579 138.692 170.859 1.00 128.78 ? 72  PHE R O   1 
ATOM   7226 C CB  . PHE E 5 610 ? 155.946 136.846 168.652 1.00 125.66 ? 72  PHE R CB  1 
ATOM   7227 C CG  . PHE E 5 610 ? 156.329 135.423 168.357 1.00 128.42 ? 72  PHE R CG  1 
ATOM   7228 C CD1 . PHE E 5 610 ? 155.651 134.372 168.953 1.00 127.74 ? 72  PHE R CD1 1 
ATOM   7229 C CD2 . PHE E 5 610 ? 157.368 135.136 167.488 1.00 128.69 ? 72  PHE R CD2 1 
ATOM   7230 C CE1 . PHE E 5 610 ? 156.000 133.063 168.687 1.00 127.81 ? 72  PHE R CE1 1 
ATOM   7231 C CE2 . PHE E 5 610 ? 157.722 133.829 167.217 1.00 129.31 ? 72  PHE R CE2 1 
ATOM   7232 C CZ  . PHE E 5 610 ? 157.037 132.791 167.818 1.00 129.37 ? 72  PHE R CZ  1 
ATOM   7233 N N   . ASN E 5 611 ? 154.385 139.209 170.721 1.00 130.28 ? 73  ASN R N   1 
ATOM   7234 C CA  . ASN E 5 611 ? 154.505 140.550 171.298 1.00 129.58 ? 73  ASN R CA  1 
ATOM   7235 C C   . ASN E 5 611 ? 155.551 141.394 170.577 1.00 130.25 ? 73  ASN R C   1 
ATOM   7236 O O   . ASN E 5 611 ? 156.133 142.311 171.160 1.00 130.41 ? 73  ASN R O   1 
ATOM   7237 C CB  . ASN E 5 611 ? 154.814 140.489 172.797 1.00 129.66 ? 73  ASN R CB  1 
ATOM   7238 C CG  . ASN E 5 611 ? 153.952 139.484 173.531 1.00 131.79 ? 73  ASN R CG  1 
ATOM   7239 O OD1 . ASN E 5 611 ? 153.666 138.403 173.019 1.00 133.72 ? 73  ASN R OD1 1 
ATOM   7240 N ND2 . ASN E 5 611 ? 153.532 139.836 174.740 1.00 130.99 ? 73  ASN R ND2 1 
ATOM   7241 N N   . LEU E 5 612 ? 155.798 141.095 169.305 1.00 132.80 ? 74  LEU R N   1 
ATOM   7242 C CA  . LEU E 5 612 ? 156.741 141.860 168.500 1.00 132.76 ? 74  LEU R CA  1 
ATOM   7243 C C   . LEU E 5 612 ? 155.962 142.998 167.853 1.00 131.37 ? 74  LEU R C   1 
ATOM   7244 O O   . LEU E 5 612 ? 155.185 142.778 166.919 1.00 132.30 ? 74  LEU R O   1 
ATOM   7245 C CB  . LEU E 5 612 ? 157.423 140.959 167.469 1.00 133.43 ? 74  LEU R CB  1 
ATOM   7246 C CG  . LEU E 5 612 ? 158.407 141.468 166.399 1.00 133.68 ? 74  LEU R CG  1 
ATOM   7247 C CD1 . LEU E 5 612 ? 157.770 142.270 165.263 1.00 131.47 ? 74  LEU R CD1 1 
ATOM   7248 C CD2 . LEU E 5 612 ? 159.517 142.276 167.060 1.00 133.87 ? 74  LEU R CD2 1 
ATOM   7249 N N   . ASN E 5 613 ? 156.143 144.208 168.371 1.00 128.22 ? 75  ASN R N   1 
ATOM   7250 C CA  . ASN E 5 613 ? 155.468 145.362 167.798 1.00 131.38 ? 75  ASN R CA  1 
ATOM   7251 C C   . ASN E 5 613 ? 156.079 145.707 166.448 1.00 130.59 ? 75  ASN R C   1 
ATOM   7252 O O   . ASN E 5 613 ? 157.297 145.638 166.261 1.00 130.64 ? 75  ASN R O   1 
ATOM   7253 C CB  . ASN E 5 613 ? 155.555 146.558 168.743 1.00 134.39 ? 75  ASN R CB  1 
ATOM   7254 C CG  . ASN E 5 613 ? 154.416 147.537 168.546 1.00 134.26 ? 75  ASN R CG  1 
ATOM   7255 O OD1 . ASN E 5 613 ? 153.938 147.734 167.429 1.00 131.11 ? 75  ASN R OD1 1 
ATOM   7256 N ND2 . ASN E 5 613 ? 153.971 148.155 169.634 1.00 134.00 ? 75  ASN R ND2 1 
ATOM   7257 N N   . TYR E 5 614 ? 155.223 146.077 165.501 1.00 135.11 ? 76  TYR R N   1 
ATOM   7258 C CA  . TYR E 5 614 ? 155.670 146.379 164.152 1.00 137.76 ? 76  TYR R CA  1 
ATOM   7259 C C   . TYR E 5 614 ? 154.661 147.312 163.502 1.00 139.35 ? 76  TYR R C   1 
ATOM   7260 O O   . TYR E 5 614 ? 153.529 147.459 163.969 1.00 139.91 ? 76  TYR R O   1 
ATOM   7261 C CB  . TYR E 5 614 ? 155.847 145.099 163.325 1.00 137.65 ? 76  TYR R CB  1 
ATOM   7262 C CG  . TYR E 5 614 ? 156.960 145.160 162.307 1.00 138.08 ? 76  TYR R CG  1 
ATOM   7263 C CD1 . TYR E 5 614 ? 156.736 145.658 161.031 1.00 136.99 ? 76  TYR R CD1 1 
ATOM   7264 C CD2 . TYR E 5 614 ? 158.236 144.713 162.621 1.00 138.29 ? 76  TYR R CD2 1 
ATOM   7265 C CE1 . TYR E 5 614 ? 157.752 145.712 160.097 1.00 137.50 ? 76  TYR R CE1 1 
ATOM   7266 C CE2 . TYR E 5 614 ? 159.259 144.763 161.694 1.00 140.52 ? 76  TYR R CE2 1 
ATOM   7267 C CZ  . TYR E 5 614 ? 159.011 145.264 160.434 1.00 140.06 ? 76  TYR R CZ  1 
ATOM   7268 O OH  . TYR E 5 614 ? 160.027 145.316 159.506 1.00 139.94 ? 76  TYR R OH  1 
ATOM   7269 N N   . VAL E 5 615 ? 155.094 147.953 162.415 1.00 143.45 ? 77  VAL R N   1 
ATOM   7270 C CA  . VAL E 5 615 ? 154.225 148.891 161.709 1.00 142.77 ? 77  VAL R CA  1 
ATOM   7271 C C   . VAL E 5 615 ? 153.032 148.164 161.103 1.00 141.66 ? 77  VAL R C   1 
ATOM   7272 O O   . VAL E 5 615 ? 151.899 148.658 161.145 1.00 142.25 ? 77  VAL R O   1 
ATOM   7273 C CB  . VAL E 5 615 ? 155.025 149.657 160.640 1.00 142.52 ? 77  VAL R CB  1 
ATOM   7274 C CG1 . VAL E 5 615 ? 154.204 150.813 160.090 1.00 141.19 ? 77  VAL R CG1 1 
ATOM   7275 C CG2 . VAL E 5 615 ? 156.341 150.156 161.218 1.00 140.85 ? 77  VAL R CG2 1 
ATOM   7276 N N   . LEU E 5 616 ? 153.263 146.982 160.532 1.00 135.94 ? 78  LEU R N   1 
ATOM   7277 C CA  . LEU E 5 616 ? 152.227 146.254 159.814 1.00 138.64 ? 78  LEU R CA  1 
ATOM   7278 C C   . LEU E 5 616 ? 151.802 144.961 160.497 1.00 137.84 ? 78  LEU R C   1 
ATOM   7279 O O   . LEU E 5 616 ? 150.916 144.272 159.979 1.00 137.73 ? 78  LEU R O   1 
ATOM   7280 C CB  . LEU E 5 616 ? 152.696 145.947 158.386 1.00 139.61 ? 78  LEU R CB  1 
ATOM   7281 C CG  . LEU E 5 616 ? 152.535 147.071 157.360 1.00 140.24 ? 78  LEU R CG  1 
ATOM   7282 C CD1 . LEU E 5 616 ? 153.740 148.001 157.380 1.00 138.69 ? 78  LEU R CD1 1 
ATOM   7283 C CD2 . LEU E 5 616 ? 152.317 146.500 155.967 1.00 138.45 ? 78  LEU R CD2 1 
ATOM   7284 N N   . CYS E 5 617 ? 152.404 144.603 161.634 1.00 125.88 ? 79  CYS R N   1 
ATOM   7285 C CA  . CYS E 5 617 ? 152.008 143.372 162.312 1.00 125.51 ? 79  CYS R CA  1 
ATOM   7286 C C   . CYS E 5 617 ? 150.571 143.452 162.809 1.00 123.18 ? 79  CYS R C   1 
ATOM   7287 O O   . CYS E 5 617 ? 149.808 142.489 162.677 1.00 124.93 ? 79  CYS R O   1 
ATOM   7288 C CB  . CYS E 5 617 ? 152.954 143.071 163.472 1.00 126.82 ? 79  CYS R CB  1 
ATOM   7289 S SG  . CYS E 5 617 ? 152.522 143.898 165.017 1.00 130.53 ? 79  CYS R SG  1 
ATOM   7290 N N   . ASN E 5 618 ? 150.183 144.589 163.379 1.00 99.30  ? 80  ASN R N   1 
ATOM   7291 C CA  . ASN E 5 618 ? 148.826 144.783 163.880 1.00 101.69 ? 80  ASN R CA  1 
ATOM   7292 C C   . ASN E 5 618 ? 147.989 145.362 162.748 1.00 103.52 ? 80  ASN R C   1 
ATOM   7293 O O   . ASN E 5 618 ? 148.048 146.561 162.465 1.00 106.19 ? 80  ASN R O   1 
ATOM   7294 C CB  . ASN E 5 618 ? 148.826 145.694 165.102 1.00 100.65 ? 80  ASN R CB  1 
ATOM   7295 C CG  . ASN E 5 618 ? 147.710 145.366 166.071 1.00 102.17 ? 80  ASN R CG  1 
ATOM   7296 O OD1 . ASN E 5 618 ? 146.951 144.420 165.863 1.00 103.08 ? 80  ASN R OD1 1 
ATOM   7297 N ND2 . ASN E 5 618 ? 147.603 146.148 167.138 1.00 100.58 ? 80  ASN R ND2 1 
ATOM   7298 N N   . LEU E 5 619 ? 147.207 144.508 162.096 1.00 94.05  ? 81  LEU R N   1 
ATOM   7299 C CA  . LEU E 5 619 ? 146.393 144.882 160.945 1.00 92.64  ? 81  LEU R CA  1 
ATOM   7300 C C   . LEU E 5 619 ? 144.973 144.355 161.101 1.00 89.84  ? 81  LEU R C   1 
ATOM   7301 O O   . LEU E 5 619 ? 144.382 143.788 160.180 1.00 88.39  ? 81  LEU R O   1 
ATOM   7302 C CB  . LEU E 5 619 ? 147.049 144.396 159.653 1.00 95.36  ? 81  LEU R CB  1 
ATOM   7303 C CG  . LEU E 5 619 ? 147.740 143.026 159.614 1.00 97.47  ? 81  LEU R CG  1 
ATOM   7304 C CD1 . LEU E 5 619 ? 146.798 141.862 159.884 1.00 96.51  ? 81  LEU R CD1 1 
ATOM   7305 C CD2 . LEU E 5 619 ? 148.448 142.839 158.280 1.00 97.82  ? 81  LEU R CD2 1 
ATOM   7306 N N   . THR E 5 620 ? 144.402 144.562 162.290 1.00 82.92  ? 82  THR R N   1 
ATOM   7307 C CA  . THR E 5 620 ? 143.063 144.059 162.573 1.00 80.92  ? 82  THR R CA  1 
ATOM   7308 C C   . THR E 5 620 ? 142.033 144.600 161.594 1.00 86.38  ? 82  THR R C   1 
ATOM   7309 O O   . THR E 5 620 ? 141.071 143.899 161.259 1.00 96.96  ? 82  THR R O   1 
ATOM   7310 C CB  . THR E 5 620 ? 142.653 144.418 163.999 1.00 81.42  ? 82  THR R CB  1 
ATOM   7311 O OG1 . THR E 5 620 ? 142.683 145.842 164.158 1.00 84.42  ? 82  THR R OG1 1 
ATOM   7312 C CG2 . THR E 5 620 ? 143.602 143.788 164.999 1.00 86.02  ? 82  THR R CG2 1 
ATOM   7313 N N   . ILE E 5 621 ? 142.204 145.839 161.131 1.00 89.07  ? 83  ILE R N   1 
ATOM   7314 C CA  . ILE E 5 621 ? 141.210 146.425 160.238 1.00 88.46  ? 83  ILE R CA  1 
ATOM   7315 C C   . ILE E 5 621 ? 141.230 145.724 158.884 1.00 95.22  ? 83  ILE R C   1 
ATOM   7316 O O   . ILE E 5 621 ? 140.178 145.513 158.265 1.00 104.91 ? 83  ILE R O   1 
ATOM   7317 C CB  . ILE E 5 621 ? 141.419 147.948 160.123 1.00 98.25  ? 83  ILE R CB  1 
ATOM   7318 C CG1 . ILE E 5 621 ? 140.067 148.653 160.036 1.00 101.18 ? 83  ILE R CG1 1 
ATOM   7319 C CG2 . ILE E 5 621 ? 142.289 148.324 158.929 1.00 101.79 ? 83  ILE R CG2 1 
ATOM   7320 C CD1 . ILE E 5 621 ? 139.186 148.397 161.230 1.00 100.92 ? 83  ILE R CD1 1 
ATOM   7321 N N   . THR E 5 622 ? 142.416 145.330 158.411 1.00 90.03  ? 84  THR R N   1 
ATOM   7322 C CA  . THR E 5 622 ? 142.489 144.580 157.163 1.00 93.32  ? 84  THR R CA  1 
ATOM   7323 C C   . THR E 5 622 ? 141.800 143.231 157.302 1.00 92.41  ? 84  THR R C   1 
ATOM   7324 O O   . THR E 5 622 ? 141.041 142.819 156.417 1.00 90.73  ? 84  THR R O   1 
ATOM   7325 C CB  . THR E 5 622 ? 143.945 144.398 156.740 1.00 91.23  ? 84  THR R CB  1 
ATOM   7326 O OG1 . THR E 5 622 ? 144.603 143.511 157.652 1.00 94.68  ? 84  THR R OG1 1 
ATOM   7327 C CG2 . THR E 5 622 ? 144.666 145.735 156.736 1.00 92.61  ? 84  THR R CG2 1 
ATOM   7328 N N   . TRP E 5 623 ? 142.039 142.540 158.418 1.00 92.45  ? 85  TRP R N   1 
ATOM   7329 C CA  . TRP E 5 623 ? 141.385 141.257 158.640 1.00 85.49  ? 85  TRP R CA  1 
ATOM   7330 C C   . TRP E 5 623 ? 139.876 141.422 158.703 1.00 82.22  ? 85  TRP R C   1 
ATOM   7331 O O   . TRP E 5 623 ? 139.136 140.599 158.162 1.00 90.44  ? 85  TRP R O   1 
ATOM   7332 C CB  . TRP E 5 623 ? 141.904 140.609 159.922 1.00 85.96  ? 85  TRP R CB  1 
ATOM   7333 C CG  . TRP E 5 623 ? 141.546 139.160 160.043 1.00 88.02  ? 85  TRP R CG  1 
ATOM   7334 C CD1 . TRP E 5 623 ? 142.352 138.099 159.766 1.00 95.91  ? 85  TRP R CD1 1 
ATOM   7335 C CD2 . TRP E 5 623 ? 140.293 138.610 160.471 1.00 88.62  ? 85  TRP R CD2 1 
ATOM   7336 N NE1 . TRP E 5 623 ? 141.683 136.923 159.994 1.00 100.00 ? 85  TRP R NE1 1 
ATOM   7337 C CE2 . TRP E 5 623 ? 140.417 137.210 160.428 1.00 93.20  ? 85  TRP R CE2 1 
ATOM   7338 C CE3 . TRP E 5 623 ? 139.082 139.164 160.890 1.00 91.88  ? 85  TRP R CE3 1 
ATOM   7339 C CZ2 . TRP E 5 623 ? 139.378 136.360 160.783 1.00 93.79  ? 85  TRP R CZ2 1 
ATOM   7340 C CZ3 . TRP E 5 623 ? 138.052 138.317 161.236 1.00 92.95  ? 85  TRP R CZ3 1 
ATOM   7341 C CH2 . TRP E 5 623 ? 138.206 136.931 161.185 1.00 93.83  ? 85  TRP R CH2 1 
ATOM   7342 N N   . GLU E 5 624 ? 139.399 142.475 159.369 1.00 81.17  ? 86  GLU R N   1 
ATOM   7343 C CA  . GLU E 5 624 ? 137.959 142.680 159.474 1.00 84.49  ? 86  GLU R CA  1 
ATOM   7344 C C   . GLU E 5 624 ? 137.340 142.963 158.113 1.00 88.94  ? 86  GLU R C   1 
ATOM   7345 O O   . GLU E 5 624 ? 136.297 142.394 157.766 1.00 101.46 ? 86  GLU R O   1 
ATOM   7346 C CB  . GLU E 5 624 ? 137.658 143.819 160.446 1.00 87.41  ? 86  GLU R CB  1 
ATOM   7347 C CG  . GLU E 5 624 ? 136.231 143.818 160.956 1.00 92.69  ? 86  GLU R CG  1 
ATOM   7348 C CD  . GLU E 5 624 ? 136.010 142.803 162.057 1.00 98.35  ? 86  GLU R CD  1 
ATOM   7349 O OE1 . GLU E 5 624 ? 137.003 142.209 162.524 1.00 95.90  ? 86  GLU R OE1 1 
ATOM   7350 O OE2 . GLU E 5 624 ? 134.842 142.594 162.449 1.00 100.35 ? 86  GLU R OE2 1 
ATOM   7351 N N   . PHE E 5 625 ? 137.977 143.827 157.320 1.00 83.39  ? 87  PHE R N   1 
ATOM   7352 C CA  . PHE E 5 625 ? 137.465 144.121 155.985 1.00 88.87  ? 87  PHE R CA  1 
ATOM   7353 C C   . PHE E 5 625 ? 137.458 142.874 155.114 1.00 96.36  ? 87  PHE R C   1 
ATOM   7354 O O   . PHE E 5 625 ? 136.514 142.639 154.353 1.00 101.01 ? 87  PHE R O   1 
ATOM   7355 C CB  . PHE E 5 625 ? 138.295 145.235 155.346 1.00 88.49  ? 87  PHE R CB  1 
ATOM   7356 C CG  . PHE E 5 625 ? 138.060 145.406 153.875 1.00 87.89  ? 87  PHE R CG  1 
ATOM   7357 C CD1 . PHE E 5 625 ? 136.906 146.005 153.409 1.00 91.20  ? 87  PHE R CD1 1 
ATOM   7358 C CD2 . PHE E 5 625 ? 139.018 145.014 152.960 1.00 86.60  ? 87  PHE R CD2 1 
ATOM   7359 C CE1 . PHE E 5 625 ? 136.695 146.172 152.058 1.00 89.21  ? 87  PHE R CE1 1 
ATOM   7360 C CE2 . PHE E 5 625 ? 138.814 145.185 151.608 1.00 95.20  ? 87  PHE R CE2 1 
ATOM   7361 C CZ  . PHE E 5 625 ? 137.650 145.764 151.157 1.00 93.72  ? 87  PHE R CZ  1 
ATOM   7362 N N   . PHE E 5 626 ? 138.491 142.048 155.233 1.00 90.23  ? 88  PHE R N   1 
ATOM   7363 C CA  . PHE E 5 626 ? 138.592 140.870 154.387 1.00 88.90  ? 88  PHE R CA  1 
ATOM   7364 C C   . PHE E 5 626 ? 137.632 139.777 154.840 1.00 78.88  ? 88  PHE R C   1 
ATOM   7365 O O   . PHE E 5 626 ? 137.123 139.014 154.013 1.00 76.51  ? 88  PHE R O   1 
ATOM   7366 C CB  . PHE E 5 626 ? 140.045 140.431 154.404 1.00 86.11  ? 88  PHE R CB  1 
ATOM   7367 C CG  . PHE E 5 626 ? 140.845 141.054 153.320 1.00 83.93  ? 88  PHE R CG  1 
ATOM   7368 C CD1 . PHE E 5 626 ? 140.250 141.945 152.452 1.00 81.02  ? 88  PHE R CD1 1 
ATOM   7369 C CD2 . PHE E 5 626 ? 142.212 140.919 153.287 1.00 87.50  ? 88  PHE R CD2 1 
ATOM   7370 C CE1 . PHE E 5 626 ? 140.977 142.568 151.475 1.00 80.29  ? 88  PHE R CE1 1 
ATOM   7371 C CE2 . PHE E 5 626 ? 142.949 141.577 152.334 1.00 87.29  ? 88  PHE R CE2 1 
ATOM   7372 C CZ  . PHE E 5 626 ? 142.334 142.386 151.416 1.00 83.81  ? 88  PHE R CZ  1 
ATOM   7373 N N   . ASN E 5 627 ? 137.351 139.712 156.141 1.00 71.97  ? 89  ASN R N   1 
ATOM   7374 C CA  . ASN E 5 627 ? 136.298 138.838 156.642 1.00 68.80  ? 89  ASN R CA  1 
ATOM   7375 C C   . ASN E 5 627 ? 134.934 139.269 156.128 1.00 69.01  ? 89  ASN R C   1 
ATOM   7376 O O   . ASN E 5 627 ? 134.112 138.431 155.738 1.00 86.80  ? 89  ASN R O   1 
ATOM   7377 C CB  . ASN E 5 627 ? 136.308 138.831 158.167 1.00 70.33  ? 89  ASN R CB  1 
ATOM   7378 C CG  . ASN E 5 627 ? 135.394 137.784 158.744 1.00 73.24  ? 89  ASN R CG  1 
ATOM   7379 O OD1 . ASN E 5 627 ? 134.965 136.867 158.048 1.00 73.30  ? 89  ASN R OD1 1 
ATOM   7380 N ND2 . ASN E 5 627 ? 135.071 137.924 160.021 1.00 79.79  ? 89  ASN R ND2 1 
ATOM   7381 N N   . ILE E 5 628 ? 134.664 140.574 156.128 1.00 59.82  ? 90  ILE R N   1 
ATOM   7382 C CA  . ILE E 5 628 ? 133.404 141.039 155.559 1.00 66.31  ? 90  ILE R CA  1 
ATOM   7383 C C   . ILE E 5 628 ? 133.349 140.703 154.076 1.00 79.72  ? 90  ILE R C   1 
ATOM   7384 O O   . ILE E 5 628 ? 132.293 140.338 153.544 1.00 92.36  ? 90  ILE R O   1 
ATOM   7385 C CB  . ILE E 5 628 ? 133.211 142.544 155.813 1.00 69.13  ? 90  ILE R CB  1 
ATOM   7386 C CG1 . ILE E 5 628 ? 133.313 142.847 157.303 1.00 79.09  ? 90  ILE R CG1 1 
ATOM   7387 C CG2 . ILE E 5 628 ? 131.854 142.992 155.317 1.00 68.85  ? 90  ILE R CG2 1 
ATOM   7388 C CD1 . ILE E 5 628 ? 132.305 142.108 158.131 1.00 77.63  ? 90  ILE R CD1 1 
ATOM   7389 N N   . LEU E 5 629 ? 134.489 140.800 153.390 1.00 79.88  ? 91  LEU R N   1 
ATOM   7390 C CA  . LEU E 5 629 ? 134.526 140.490 151.965 1.00 82.20  ? 91  LEU R CA  1 
ATOM   7391 C C   . LEU E 5 629 ? 134.216 139.020 151.706 1.00 86.66  ? 91  LEU R C   1 
ATOM   7392 O O   . LEU E 5 629 ? 133.427 138.692 150.813 1.00 91.09  ? 91  LEU R O   1 
ATOM   7393 C CB  . LEU E 5 629 ? 135.886 140.866 151.381 1.00 78.19  ? 91  LEU R CB  1 
ATOM   7394 C CG  . LEU E 5 629 ? 135.992 140.749 149.863 1.00 73.45  ? 91  LEU R CG  1 
ATOM   7395 C CD1 . LEU E 5 629 ? 134.855 141.504 149.209 1.00 75.27  ? 91  LEU R CD1 1 
ATOM   7396 C CD2 . LEU E 5 629 ? 137.328 141.286 149.386 1.00 82.17  ? 91  LEU R CD2 1 
ATOM   7397 N N   . THR E 5 630 ? 134.828 138.116 152.477 1.00 76.85  ? 92  THR R N   1 
ATOM   7398 C CA  . THR E 5 630 ? 134.549 136.698 152.268 1.00 54.20  ? 92  THR R CA  1 
ATOM   7399 C C   . THR E 5 630 ? 133.121 136.349 152.660 1.00 49.25  ? 92  THR R C   1 
ATOM   7400 O O   . THR E 5 630 ? 132.496 135.507 152.007 1.00 78.93  ? 92  THR R O   1 
ATOM   7401 C CB  . THR E 5 630 ? 135.545 135.812 153.022 1.00 56.71  ? 92  THR R CB  1 
ATOM   7402 O OG1 . THR E 5 630 ? 135.143 134.443 152.905 1.00 69.95  ? 92  THR R OG1 1 
ATOM   7403 C CG2 . THR E 5 630 ? 135.602 136.157 154.477 1.00 65.59  ? 92  THR R CG2 1 
ATOM   7404 N N   . PHE E 5 631 ? 132.575 136.996 153.692 1.00 58.66  ? 93  PHE R N   1 
ATOM   7405 C CA  . PHE E 5 631 ? 131.174 136.772 154.030 1.00 64.57  ? 93  PHE R CA  1 
ATOM   7406 C C   . PHE E 5 631 ? 130.257 137.211 152.897 1.00 72.29  ? 93  PHE R C   1 
ATOM   7407 O O   . PHE E 5 631 ? 129.315 136.493 152.536 1.00 94.17  ? 93  PHE R O   1 
ATOM   7408 C CB  . PHE E 5 631 ? 130.817 137.511 155.315 1.00 73.04  ? 93  PHE R CB  1 
ATOM   7409 C CG  . PHE E 5 631 ? 130.847 136.648 156.532 1.00 73.35  ? 93  PHE R CG  1 
ATOM   7410 C CD1 . PHE E 5 631 ? 132.046 136.184 157.035 1.00 74.68  ? 93  PHE R CD1 1 
ATOM   7411 C CD2 . PHE E 5 631 ? 129.676 136.291 157.167 1.00 77.56  ? 93  PHE R CD2 1 
ATOM   7412 C CE1 . PHE E 5 631 ? 132.077 135.387 158.154 1.00 79.43  ? 93  PHE R CE1 1 
ATOM   7413 C CE2 . PHE E 5 631 ? 129.701 135.493 158.285 1.00 86.36  ? 93  PHE R CE2 1 
ATOM   7414 C CZ  . PHE E 5 631 ? 130.903 135.040 158.781 1.00 86.40  ? 93  PHE R CZ  1 
ATOM   7415 N N   . TRP E 5 632 ? 130.518 138.384 152.320 1.00 69.30  ? 94  TRP R N   1 
ATOM   7416 C CA  . TRP E 5 632 ? 129.678 138.865 151.229 1.00 76.78  ? 94  TRP R CA  1 
ATOM   7417 C C   . TRP E 5 632 ? 129.810 137.979 149.999 1.00 79.80  ? 94  TRP R C   1 
ATOM   7418 O O   . TRP E 5 632 ? 128.817 137.713 149.312 1.00 87.65  ? 94  TRP R O   1 
ATOM   7419 C CB  . TRP E 5 632 ? 130.027 140.312 150.894 1.00 83.27  ? 94  TRP R CB  1 
ATOM   7420 C CG  . TRP E 5 632 ? 129.280 141.296 151.728 1.00 83.94  ? 94  TRP R CG  1 
ATOM   7421 C CD1 . TRP E 5 632 ? 129.801 142.145 152.654 1.00 88.52  ? 94  TRP R CD1 1 
ATOM   7422 C CD2 . TRP E 5 632 ? 127.869 141.532 151.715 1.00 79.72  ? 94  TRP R CD2 1 
ATOM   7423 N NE1 . TRP E 5 632 ? 128.804 142.897 153.221 1.00 86.23  ? 94  TRP R NE1 1 
ATOM   7424 C CE2 . TRP E 5 632 ? 127.607 142.541 152.659 1.00 79.32  ? 94  TRP R CE2 1 
ATOM   7425 C CE3 . TRP E 5 632 ? 126.803 140.991 150.994 1.00 82.80  ? 94  TRP R CE3 1 
ATOM   7426 C CZ2 . TRP E 5 632 ? 126.326 143.016 152.904 1.00 79.84  ? 94  TRP R CZ2 1 
ATOM   7427 C CZ3 . TRP E 5 632 ? 125.530 141.465 151.239 1.00 88.58  ? 94  TRP R CZ3 1 
ATOM   7428 C CH2 . TRP E 5 632 ? 125.302 142.468 152.185 1.00 85.02  ? 94  TRP R CH2 1 
ATOM   7429 N N   . LEU E 5 633 ? 131.022 137.510 149.706 1.00 69.19  ? 95  LEU R N   1 
ATOM   7430 C CA  . LEU E 5 633 ? 131.204 136.632 148.557 1.00 65.02  ? 95  LEU R CA  1 
ATOM   7431 C C   . LEU E 5 633 ? 130.511 135.293 148.766 1.00 67.33  ? 95  LEU R C   1 
ATOM   7432 O O   . LEU E 5 633 ? 129.929 134.741 147.828 1.00 75.96  ? 95  LEU R O   1 
ATOM   7433 C CB  . LEU E 5 633 ? 132.689 136.442 148.274 1.00 66.75  ? 95  LEU R CB  1 
ATOM   7434 C CG  . LEU E 5 633 ? 133.338 137.723 147.757 1.00 73.92  ? 95  LEU R CG  1 
ATOM   7435 C CD1 . LEU E 5 633 ? 134.834 137.559 147.638 1.00 70.59  ? 95  LEU R CD1 1 
ATOM   7436 C CD2 . LEU E 5 633 ? 132.729 138.134 146.430 1.00 77.02  ? 95  LEU R CD2 1 
ATOM   7437 N N   . ASN E 5 634 ? 130.556 134.754 149.986 1.00 66.57  ? 96  ASN R N   1 
ATOM   7438 C CA  . ASN E 5 634 ? 129.840 133.515 150.270 1.00 63.62  ? 96  ASN R CA  1 
ATOM   7439 C C   . ASN E 5 634 ? 128.332 133.707 150.152 1.00 64.59  ? 96  ASN R C   1 
ATOM   7440 O O   . ASN E 5 634 ? 127.627 132.840 149.617 1.00 71.42  ? 96  ASN R O   1 
ATOM   7441 C CB  . ASN E 5 634 ? 130.214 133.010 151.659 1.00 52.30  ? 96  ASN R CB  1 
ATOM   7442 C CG  . ASN E 5 634 ? 129.807 131.578 151.883 1.00 74.73  ? 96  ASN R CG  1 
ATOM   7443 O OD1 . ASN E 5 634 ? 130.126 130.698 151.085 1.00 80.01  ? 96  ASN R OD1 1 
ATOM   7444 N ND2 . ASN E 5 634 ? 129.099 131.330 152.976 1.00 81.37  ? 96  ASN R ND2 1 
ATOM   7445 N N   . SER E 5 635 ? 127.820 134.837 150.644 1.00 60.84  ? 97  SER R N   1 
ATOM   7446 C CA  . SER E 5 635 ? 126.396 135.119 150.502 1.00 62.04  ? 97  SER R CA  1 
ATOM   7447 C C   . SER E 5 635 ? 126.008 135.240 149.037 1.00 65.72  ? 97  SER R C   1 
ATOM   7448 O O   . SER E 5 635 ? 124.954 134.743 148.623 1.00 75.34  ? 97  SER R O   1 
ATOM   7449 C CB  . SER E 5 635 ? 126.031 136.393 151.260 1.00 73.28  ? 97  SER R CB  1 
ATOM   7450 O OG  . SER E 5 635 ? 126.335 136.269 152.638 1.00 85.83  ? 97  SER R OG  1 
ATOM   7451 N N   . LEU E 5 636 ? 126.847 135.895 148.233 1.00 77.73  ? 98  LEU R N   1 
ATOM   7452 C CA  . LEU E 5 636 ? 126.561 136.003 146.807 1.00 78.33  ? 98  LEU R CA  1 
ATOM   7453 C C   . LEU E 5 636 ? 126.628 134.642 146.129 1.00 81.74  ? 98  LEU R C   1 
ATOM   7454 O O   . LEU E 5 636 ? 125.849 134.364 145.214 1.00 85.25  ? 98  LEU R O   1 
ATOM   7455 C CB  . LEU E 5 636 ? 127.523 136.983 146.140 1.00 80.45  ? 98  LEU R CB  1 
ATOM   7456 C CG  . LEU E 5 636 ? 127.159 137.341 144.698 1.00 85.87  ? 98  LEU R CG  1 
ATOM   7457 C CD1 . LEU E 5 636 ? 125.688 137.706 144.593 1.00 88.41  ? 98  LEU R CD1 1 
ATOM   7458 C CD2 . LEU E 5 636 ? 128.029 138.475 144.187 1.00 88.51  ? 98  LEU R CD2 1 
ATOM   7459 N N   . LEU E 5 637 ? 127.550 133.783 146.564 1.00 75.86  ? 99  LEU R N   1 
ATOM   7460 C CA  . LEU E 5 637 ? 127.620 132.427 146.029 1.00 61.39  ? 99  LEU R CA  1 
ATOM   7461 C C   . LEU E 5 637 ? 126.332 131.669 146.304 1.00 52.54  ? 99  LEU R C   1 
ATOM   7462 O O   . LEU E 5 637 ? 125.797 130.983 145.426 1.00 65.54  ? 99  LEU R O   1 
ATOM   7463 C CB  . LEU E 5 637 ? 128.809 131.690 146.640 1.00 55.55  ? 99  LEU R CB  1 
ATOM   7464 C CG  . LEU E 5 637 ? 128.998 130.233 146.233 1.00 49.06  ? 99  LEU R CG  1 
ATOM   7465 C CD1 . LEU E 5 637 ? 129.144 130.123 144.732 1.00 61.09  ? 99  LEU R CD1 1 
ATOM   7466 C CD2 . LEU E 5 637 ? 130.207 129.649 146.929 1.00 61.15  ? 99  LEU R CD2 1 
ATOM   7467 N N   . THR E 5 638 ? 125.819 131.781 147.527 1.00 54.12  ? 100 THR R N   1 
ATOM   7468 C CA  . THR E 5 638 ? 124.591 131.071 147.861 1.00 57.14  ? 100 THR R CA  1 
ATOM   7469 C C   . THR E 5 638 ? 123.390 131.653 147.124 1.00 63.79  ? 100 THR R C   1 
ATOM   7470 O O   . THR E 5 638 ? 122.514 130.907 146.678 1.00 75.20  ? 100 THR R O   1 
ATOM   7471 C CB  . THR E 5 638 ? 124.361 131.086 149.364 1.00 65.80  ? 100 THR R CB  1 
ATOM   7472 O OG1 . THR E 5 638 ? 125.604 130.842 150.031 1.00 75.17  ? 100 THR R OG1 1 
ATOM   7473 C CG2 . THR E 5 638 ? 123.379 130.001 149.739 1.00 70.97  ? 100 THR R CG2 1 
ATOM   7474 N N   . VAL E 5 639 ? 123.334 132.979 146.973 1.00 62.77  ? 101 VAL R N   1 
ATOM   7475 C CA  . VAL E 5 639 ? 122.244 133.581 146.206 1.00 58.30  ? 101 VAL R CA  1 
ATOM   7476 C C   . VAL E 5 639 ? 122.340 133.191 144.735 1.00 66.46  ? 101 VAL R C   1 
ATOM   7477 O O   . VAL E 5 639 ? 121.319 133.045 144.052 1.00 76.39  ? 101 VAL R O   1 
ATOM   7478 C CB  . VAL E 5 639 ? 122.236 135.110 146.389 1.00 64.13  ? 101 VAL R CB  1 
ATOM   7479 C CG1 . VAL E 5 639 ? 121.175 135.751 145.513 1.00 66.20  ? 101 VAL R CG1 1 
ATOM   7480 C CG2 . VAL E 5 639 ? 121.989 135.467 147.841 1.00 70.28  ? 101 VAL R CG2 1 
ATOM   7481 N N   . PHE E 5 640 ? 123.554 133.012 144.218 1.00 62.89  ? 102 PHE R N   1 
ATOM   7482 C CA  . PHE E 5 640 ? 123.707 132.596 142.831 1.00 61.54  ? 102 PHE R CA  1 
ATOM   7483 C C   . PHE E 5 640 ? 123.283 131.145 142.639 1.00 67.79  ? 102 PHE R C   1 
ATOM   7484 O O   . PHE E 5 640 ? 122.637 130.809 141.638 1.00 79.97  ? 102 PHE R O   1 
ATOM   7485 C CB  . PHE E 5 640 ? 125.149 132.809 142.391 1.00 57.85  ? 102 PHE R CB  1 
ATOM   7486 C CG  . PHE E 5 640 ? 125.551 131.967 141.234 1.00 56.13  ? 102 PHE R CG  1 
ATOM   7487 C CD1 . PHE E 5 640 ? 125.071 132.237 139.969 1.00 68.68  ? 102 PHE R CD1 1 
ATOM   7488 C CD2 . PHE E 5 640 ? 126.407 130.902 141.408 1.00 63.70  ? 102 PHE R CD2 1 
ATOM   7489 C CE1 . PHE E 5 640 ? 125.439 131.458 138.902 1.00 78.13  ? 102 PHE R CE1 1 
ATOM   7490 C CE2 . PHE E 5 640 ? 126.775 130.123 140.347 1.00 68.30  ? 102 PHE R CE2 1 
ATOM   7491 C CZ  . PHE E 5 640 ? 126.299 130.401 139.091 1.00 73.48  ? 102 PHE R CZ  1 
ATOM   7492 N N   . TYR E 5 641 ? 123.647 130.269 143.581 1.00 69.16  ? 103 TYR R N   1 
ATOM   7493 C CA  . TYR E 5 641 ? 123.071 128.927 143.606 1.00 57.53  ? 103 TYR R CA  1 
ATOM   7494 C C   . TYR E 5 641 ? 121.554 129.004 143.614 1.00 53.71  ? 103 TYR R C   1 
ATOM   7495 O O   . TYR E 5 641 ? 120.874 128.285 142.872 1.00 71.08  ? 103 TYR R O   1 
ATOM   7496 C CB  . TYR E 5 641 ? 123.544 128.165 144.844 1.00 57.79  ? 103 TYR R CB  1 
ATOM   7497 C CG  . TYR E 5 641 ? 124.981 127.711 144.833 1.00 57.11  ? 103 TYR R CG  1 
ATOM   7498 C CD1 . TYR E 5 641 ? 125.793 127.924 143.735 1.00 63.08  ? 103 TYR R CD1 1 
ATOM   7499 C CD2 . TYR E 5 641 ? 125.527 127.072 145.937 1.00 59.93  ? 103 TYR R CD2 1 
ATOM   7500 C CE1 . TYR E 5 641 ? 127.106 127.506 143.732 1.00 68.71  ? 103 TYR R CE1 1 
ATOM   7501 C CE2 . TYR E 5 641 ? 126.834 126.657 145.945 1.00 62.81  ? 103 TYR R CE2 1 
ATOM   7502 C CZ  . TYR E 5 641 ? 127.621 126.875 144.841 1.00 69.27  ? 103 TYR R CZ  1 
ATOM   7503 O OH  . TYR E 5 641 ? 128.931 126.457 144.847 1.00 75.04  ? 103 TYR R OH  1 
ATOM   7504 N N   . CYS E 5 642 ? 121.014 129.885 144.456 1.00 53.78  ? 104 CYS R N   1 
ATOM   7505 C CA  . CYS E 5 642 ? 119.578 130.095 144.560 1.00 59.48  ? 104 CYS R CA  1 
ATOM   7506 C C   . CYS E 5 642 ? 118.959 130.404 143.205 1.00 66.76  ? 104 CYS R C   1 
ATOM   7507 O O   . CYS E 5 642 ? 117.982 129.771 142.793 1.00 78.03  ? 104 CYS R O   1 
ATOM   7508 C CB  . CYS E 5 642 ? 119.328 131.245 145.534 1.00 75.42  ? 104 CYS R CB  1 
ATOM   7509 S SG  . CYS E 5 642 ? 117.859 131.147 146.523 1.00 89.19  ? 104 CYS R SG  1 
ATOM   7510 N N   . ILE E 5 643 ? 119.517 131.387 142.500 1.00 67.52  ? 105 ILE R N   1 
ATOM   7511 C CA  . ILE E 5 643 ? 118.903 131.831 141.253 1.00 70.34  ? 105 ILE R CA  1 
ATOM   7512 C C   . ILE E 5 643 ? 119.073 130.784 140.157 1.00 77.88  ? 105 ILE R C   1 
ATOM   7513 O O   . ILE E 5 643 ? 118.142 130.529 139.384 1.00 87.77  ? 105 ILE R O   1 
ATOM   7514 C CB  . ILE E 5 643 ? 119.443 133.212 140.831 1.00 76.83  ? 105 ILE R CB  1 
ATOM   7515 C CG1 . ILE E 5 643 ? 120.911 133.145 140.406 1.00 82.29  ? 105 ILE R CG1 1 
ATOM   7516 C CG2 . ILE E 5 643 ? 119.238 134.229 141.942 1.00 78.23  ? 105 ILE R CG2 1 
ATOM   7517 C CD1 . ILE E 5 643 ? 121.288 134.161 139.352 1.00 82.54  ? 105 ILE R CD1 1 
ATOM   7518 N N   . LYS E 5 644 ? 120.248 130.154 140.063 1.00 56.50  ? 106 LYS R N   1 
ATOM   7519 C CA  . LYS E 5 644 ? 120.473 129.221 138.964 1.00 60.75  ? 106 LYS R CA  1 
ATOM   7520 C C   . LYS E 5 644 ? 119.692 127.926 139.154 1.00 61.35  ? 106 LYS R C   1 
ATOM   7521 O O   . LYS E 5 644 ? 119.038 127.445 138.222 1.00 64.79  ? 106 LYS R O   1 
ATOM   7522 C CB  . LYS E 5 644 ? 121.960 128.924 138.802 1.00 52.72  ? 106 LYS R CB  1 
ATOM   7523 C CG  . LYS E 5 644 ? 122.396 128.923 137.353 1.00 61.24  ? 106 LYS R CG  1 
ATOM   7524 C CD  . LYS E 5 644 ? 123.896 128.906 137.212 1.00 61.38  ? 106 LYS R CD  1 
ATOM   7525 C CE  . LYS E 5 644 ? 124.307 128.908 135.752 1.00 63.71  ? 106 LYS R CE  1 
ATOM   7526 N NZ  . LYS E 5 644 ? 123.237 128.362 134.874 1.00 66.18  ? 106 LYS R NZ  1 
ATOM   7527 N N   . VAL E 5 645 ? 119.751 127.342 140.352 1.00 65.55  ? 107 VAL R N   1 
ATOM   7528 C CA  . VAL E 5 645 ? 119.146 126.030 140.558 1.00 54.01  ? 107 VAL R CA  1 
ATOM   7529 C C   . VAL E 5 645 ? 117.628 126.116 140.484 1.00 45.48  ? 107 VAL R C   1 
ATOM   7530 O O   . VAL E 5 645 ? 116.968 125.210 139.961 1.00 63.82  ? 107 VAL R O   1 
ATOM   7531 C CB  . VAL E 5 645 ? 119.620 125.431 141.893 1.00 56.51  ? 107 VAL R CB  1 
ATOM   7532 C CG1 . VAL E 5 645 ? 118.913 124.119 142.170 1.00 60.72  ? 107 VAL R CG1 1 
ATOM   7533 C CG2 . VAL E 5 645 ? 121.124 125.232 141.869 1.00 60.50  ? 107 VAL R CG2 1 
ATOM   7534 N N   . SER E 5 646 ? 117.051 127.197 141.000 1.00 64.85  ? 108 SER R N   1 
ATOM   7535 C CA  . SER E 5 646 ? 115.601 127.343 140.997 1.00 75.70  ? 108 SER R CA  1 
ATOM   7536 C C   . SER E 5 646 ? 115.068 127.339 139.571 1.00 77.70  ? 108 SER R C   1 
ATOM   7537 O O   . SER E 5 646 ? 115.602 128.020 138.692 1.00 75.32  ? 108 SER R O   1 
ATOM   7538 C CB  . SER E 5 646 ? 115.198 128.634 141.708 1.00 83.24  ? 108 SER R CB  1 
ATOM   7539 O OG  . SER E 5 646 ? 114.923 129.662 140.774 1.00 87.57  ? 108 SER R OG  1 
ATOM   7540 N N   . SER E 5 647 ? 114.011 126.566 139.347 1.00 112.50 ? 109 SER R N   1 
ATOM   7541 C CA  . SER E 5 647 ? 113.419 126.387 138.027 1.00 114.25 ? 109 SER R CA  1 
ATOM   7542 C C   . SER E 5 647 ? 112.083 127.114 137.908 1.00 117.03 ? 109 SER R C   1 
ATOM   7543 O O   . SER E 5 647 ? 111.149 126.628 137.269 1.00 122.74 ? 109 SER R O   1 
ATOM   7544 C CB  . SER E 5 647 ? 113.247 124.904 137.710 1.00 115.90 ? 109 SER R CB  1 
ATOM   7545 O OG  . SER E 5 647 ? 112.416 124.271 138.667 1.00 114.91 ? 109 SER R OG  1 
ATOM   7546 N N   . PHE E 5 648 ? 111.978 128.285 138.530 1.00 122.81 ? 110 PHE R N   1 
ATOM   7547 C CA  . PHE E 5 648 ? 110.779 129.095 138.389 1.00 126.42 ? 110 PHE R CA  1 
ATOM   7548 C C   . PHE E 5 648 ? 110.640 129.581 136.951 1.00 129.44 ? 110 PHE R C   1 
ATOM   7549 O O   . PHE E 5 648 ? 111.607 129.616 136.188 1.00 128.29 ? 110 PHE R O   1 
ATOM   7550 C CB  . PHE E 5 648 ? 110.816 130.284 139.347 1.00 125.81 ? 110 PHE R CB  1 
ATOM   7551 C CG  . PHE E 5 648 ? 109.886 130.148 140.517 1.00 127.47 ? 110 PHE R CG  1 
ATOM   7552 C CD1 . PHE E 5 648 ? 110.019 129.096 141.407 1.00 127.78 ? 110 PHE R CD1 1 
ATOM   7553 C CD2 . PHE E 5 648 ? 108.875 131.072 140.727 1.00 126.55 ? 110 PHE R CD2 1 
ATOM   7554 C CE1 . PHE E 5 648 ? 109.163 128.967 142.485 1.00 126.61 ? 110 PHE R CE1 1 
ATOM   7555 C CE2 . PHE E 5 648 ? 108.016 130.950 141.803 1.00 127.10 ? 110 PHE R CE2 1 
ATOM   7556 C CZ  . PHE E 5 648 ? 108.160 129.896 142.683 1.00 126.72 ? 110 PHE R CZ  1 
ATOM   7557 N N   . THR E 5 649 ? 109.410 129.937 136.576 1.00 144.81 ? 111 THR R N   1 
ATOM   7558 C CA  . THR E 5 649 ? 109.108 130.383 135.221 1.00 144.12 ? 111 THR R CA  1 
ATOM   7559 C C   . THR E 5 649 ? 108.425 131.747 135.198 1.00 142.44 ? 111 THR R C   1 
ATOM   7560 O O   . THR E 5 649 ? 107.837 132.123 134.179 1.00 141.26 ? 111 THR R O   1 
ATOM   7561 C CB  . THR E 5 649 ? 108.241 129.351 134.495 1.00 145.06 ? 111 THR R CB  1 
ATOM   7562 O OG1 . THR E 5 649 ? 107.057 129.095 135.261 1.00 143.47 ? 111 THR R OG1 1 
ATOM   7563 C CG2 . THR E 5 649 ? 109.007 128.050 134.300 1.00 142.94 ? 111 THR R CG2 1 
ATOM   7564 N N   . HIS E 5 650 ? 108.486 132.494 136.297 1.00 149.89 ? 112 HIS R N   1 
ATOM   7565 C CA  . HIS E 5 650 ? 107.859 133.807 136.341 1.00 150.61 ? 112 HIS R CA  1 
ATOM   7566 C C   . HIS E 5 650 ? 108.595 134.779 135.426 1.00 151.28 ? 112 HIS R C   1 
ATOM   7567 O O   . HIS E 5 650 ? 109.828 134.805 135.384 1.00 151.53 ? 112 HIS R O   1 
ATOM   7568 C CB  . HIS E 5 650 ? 107.839 134.339 137.773 1.00 149.74 ? 112 HIS R CB  1 
ATOM   7569 C CG  . HIS E 5 650 ? 106.930 135.512 137.969 1.00 150.53 ? 112 HIS R CG  1 
ATOM   7570 N ND1 . HIS E 5 650 ? 107.371 136.816 137.905 1.00 150.07 ? 112 HIS R ND1 1 
ATOM   7571 C CD2 . HIS E 5 650 ? 105.603 135.577 138.231 1.00 150.83 ? 112 HIS R CD2 1 
ATOM   7572 C CE1 . HIS E 5 650 ? 106.355 137.633 138.119 1.00 149.25 ? 112 HIS R CE1 1 
ATOM   7573 N NE2 . HIS E 5 650 ? 105.271 136.906 138.319 1.00 150.63 ? 112 HIS R NE2 1 
ATOM   7574 N N   . HIS E 5 651 ? 107.826 135.580 134.686 1.00 157.24 ? 113 HIS R N   1 
ATOM   7575 C CA  . HIS E 5 651 ? 108.421 136.487 133.709 1.00 156.98 ? 113 HIS R CA  1 
ATOM   7576 C C   . HIS E 5 651 ? 109.305 137.529 134.385 1.00 153.76 ? 113 HIS R C   1 
ATOM   7577 O O   . HIS E 5 651 ? 110.429 137.784 133.942 1.00 150.09 ? 113 HIS R O   1 
ATOM   7578 C CB  . HIS E 5 651 ? 107.323 137.159 132.882 1.00 156.51 ? 113 HIS R CB  1 
ATOM   7579 C CG  . HIS E 5 651 ? 106.114 137.541 133.677 1.00 157.46 ? 113 HIS R CG  1 
ATOM   7580 N ND1 . HIS E 5 651 ? 105.947 138.796 134.222 1.00 157.45 ? 113 HIS R ND1 1 
ATOM   7581 C CD2 . HIS E 5 651 ? 105.009 136.835 134.014 1.00 155.81 ? 113 HIS R CD2 1 
ATOM   7582 C CE1 . HIS E 5 651 ? 104.793 138.846 134.863 1.00 157.80 ? 113 HIS R CE1 1 
ATOM   7583 N NE2 . HIS E 5 651 ? 104.204 137.668 134.752 1.00 156.97 ? 113 HIS R NE2 1 
ATOM   7584 N N   . ILE E 5 652 ? 108.814 138.141 135.464 1.00 147.11 ? 114 ILE R N   1 
ATOM   7585 C CA  . ILE E 5 652 ? 109.604 139.150 136.165 1.00 148.05 ? 114 ILE R CA  1 
ATOM   7586 C C   . ILE E 5 652 ? 110.776 138.502 136.894 1.00 148.22 ? 114 ILE R C   1 
ATOM   7587 O O   . ILE E 5 652 ? 111.887 139.051 136.930 1.00 149.02 ? 114 ILE R O   1 
ATOM   7588 C CB  . ILE E 5 652 ? 108.709 139.954 137.125 1.00 150.14 ? 114 ILE R CB  1 
ATOM   7589 C CG1 . ILE E 5 652 ? 107.664 140.747 136.337 1.00 150.15 ? 114 ILE R CG1 1 
ATOM   7590 C CG2 . ILE E 5 652 ? 109.543 140.889 137.988 1.00 149.91 ? 114 ILE R CG2 1 
ATOM   7591 C CD1 . ILE E 5 652 ? 106.662 141.472 137.208 1.00 150.19 ? 114 ILE R CD1 1 
ATOM   7592 N N   . PHE E 5 653 ? 110.550 137.331 137.493 1.00 146.77 ? 115 PHE R N   1 
ATOM   7593 C CA  . PHE E 5 653 ? 111.634 136.640 138.180 1.00 147.54 ? 115 PHE R CA  1 
ATOM   7594 C C   . PHE E 5 653 ? 112.739 136.249 137.208 1.00 145.44 ? 115 PHE R C   1 
ATOM   7595 O O   . PHE E 5 653 ? 113.923 136.435 137.499 1.00 144.23 ? 115 PHE R O   1 
ATOM   7596 C CB  . PHE E 5 653 ? 111.097 135.412 138.914 1.00 147.54 ? 115 PHE R CB  1 
ATOM   7597 C CG  . PHE E 5 653 ? 110.458 135.731 140.236 1.00 148.84 ? 115 PHE R CG  1 
ATOM   7598 C CD1 . PHE E 5 653 ? 110.696 136.945 140.860 1.00 145.41 ? 115 PHE R CD1 1 
ATOM   7599 C CD2 . PHE E 5 653 ? 109.618 134.819 140.854 1.00 147.69 ? 115 PHE R CD2 1 
ATOM   7600 C CE1 . PHE E 5 653 ? 110.110 137.244 142.076 1.00 143.42 ? 115 PHE R CE1 1 
ATOM   7601 C CE2 . PHE E 5 653 ? 109.029 135.113 142.071 1.00 147.61 ? 115 PHE R CE2 1 
ATOM   7602 C CZ  . PHE E 5 653 ? 109.276 136.326 142.682 1.00 145.52 ? 115 PHE R CZ  1 
ATOM   7603 N N   . LEU E 5 654 ? 112.371 135.731 136.035 1.00 139.91 ? 116 LEU R N   1 
ATOM   7604 C CA  . LEU E 5 654 ? 113.373 135.371 135.035 1.00 141.52 ? 116 LEU R CA  1 
ATOM   7605 C C   . LEU E 5 654 ? 114.048 136.611 134.456 1.00 137.49 ? 116 LEU R C   1 
ATOM   7606 O O   . LEU E 5 654 ? 115.241 136.584 134.124 1.00 136.13 ? 116 LEU R O   1 
ATOM   7607 C CB  . LEU E 5 654 ? 112.718 134.545 133.932 1.00 142.57 ? 116 LEU R CB  1 
ATOM   7608 C CG  . LEU E 5 654 ? 112.904 133.032 134.006 1.00 140.22 ? 116 LEU R CG  1 
ATOM   7609 C CD1 . LEU E 5 654 ? 112.150 132.490 135.199 1.00 139.36 ? 116 LEU R CD1 1 
ATOM   7610 C CD2 . LEU E 5 654 ? 112.426 132.372 132.724 1.00 137.69 ? 116 LEU R CD2 1 
ATOM   7611 N N   . TRP E 5 655 ? 113.279 137.686 134.285 1.00 136.60 ? 117 TRP R N   1 
ATOM   7612 C CA  . TRP E 5 655 ? 113.815 138.998 133.943 1.00 138.83 ? 117 TRP R CA  1 
ATOM   7613 C C   . TRP E 5 655 ? 114.987 139.344 134.854 1.00 139.09 ? 117 TRP R C   1 
ATOM   7614 O O   . TRP E 5 655 ? 116.139 139.506 134.412 1.00 138.42 ? 117 TRP R O   1 
ATOM   7615 C CB  . TRP E 5 655 ? 112.679 140.017 134.098 1.00 140.62 ? 117 TRP R CB  1 
ATOM   7616 C CG  . TRP E 5 655 ? 113.034 141.472 134.153 1.00 142.57 ? 117 TRP R CG  1 
ATOM   7617 C CD1 . TRP E 5 655 ? 112.379 142.433 134.868 1.00 142.02 ? 117 TRP R CD1 1 
ATOM   7618 C CD2 . TRP E 5 655 ? 113.978 142.170 133.330 1.00 142.76 ? 117 TRP R CD2 1 
ATOM   7619 N NE1 . TRP E 5 655 ? 112.929 143.665 134.629 1.00 141.89 ? 117 TRP R NE1 1 
ATOM   7620 C CE2 . TRP E 5 655 ? 113.905 143.534 133.677 1.00 142.70 ? 117 TRP R CE2 1 
ATOM   7621 C CE3 . TRP E 5 655 ? 114.907 141.770 132.367 1.00 141.05 ? 117 TRP R CE3 1 
ATOM   7622 C CZ2 . TRP E 5 655 ? 114.724 144.496 133.095 1.00 140.49 ? 117 TRP R CZ2 1 
ATOM   7623 C CZ3 . TRP E 5 655 ? 115.711 142.725 131.790 1.00 140.50 ? 117 TRP R CZ3 1 
ATOM   7624 C CH2 . TRP E 5 655 ? 115.622 144.072 132.158 1.00 140.31 ? 117 TRP R CH2 1 
ATOM   7625 N N   . LEU E 5 656 ? 114.695 139.418 136.155 1.00 140.00 ? 118 LEU R N   1 
ATOM   7626 C CA  . LEU E 5 656 ? 115.727 139.693 137.145 1.00 140.76 ? 118 LEU R CA  1 
ATOM   7627 C C   . LEU E 5 656 ? 116.848 138.668 137.067 1.00 140.28 ? 118 LEU R C   1 
ATOM   7628 O O   . LEU E 5 656 ? 118.020 139.015 137.229 1.00 140.53 ? 118 LEU R O   1 
ATOM   7629 C CB  . LEU E 5 656 ? 115.116 139.714 138.546 1.00 140.89 ? 118 LEU R CB  1 
ATOM   7630 C CG  . LEU E 5 656 ? 116.035 140.128 139.697 1.00 140.32 ? 118 LEU R CG  1 
ATOM   7631 C CD1 . LEU E 5 656 ? 116.519 141.558 139.514 1.00 139.32 ? 118 LEU R CD1 1 
ATOM   7632 C CD2 . LEU E 5 656 ? 115.322 139.965 141.031 1.00 140.30 ? 118 LEU R CD2 1 
ATOM   7633 N N   . ARG E 5 657 ? 116.508 137.404 136.807 1.00 127.00 ? 119 ARG R N   1 
ATOM   7634 C CA  . ARG E 5 657 ? 117.520 136.358 136.726 1.00 127.65 ? 119 ARG R CA  1 
ATOM   7635 C C   . ARG E 5 657 ? 118.567 136.696 135.674 1.00 127.07 ? 119 ARG R C   1 
ATOM   7636 O O   . ARG E 5 657 ? 119.744 136.902 135.998 1.00 126.96 ? 119 ARG R O   1 
ATOM   7637 C CB  . ARG E 5 657 ? 116.864 135.008 136.429 1.00 126.80 ? 119 ARG R CB  1 
ATOM   7638 C CG  . ARG E 5 657 ? 116.228 134.345 137.643 1.00 125.31 ? 119 ARG R CG  1 
ATOM   7639 C CD  . ARG E 5 657 ? 116.645 132.889 137.796 1.00 127.54 ? 119 ARG R CD  1 
ATOM   7640 N NE  . ARG E 5 657 ? 116.461 132.110 136.576 1.00 127.07 ? 119 ARG R NE  1 
ATOM   7641 C CZ  . ARG E 5 657 ? 117.449 131.707 135.788 1.00 125.72 ? 119 ARG R CZ  1 
ATOM   7642 N NH1 . ARG E 5 657 ? 118.710 132.005 136.053 1.00 126.88 ? 119 ARG R NH1 1 
ATOM   7643 N NH2 . ARG E 5 657 ? 117.164 130.987 134.708 1.00 124.11 ? 119 ARG R NH2 1 
ATOM   7644 N N   . TRP E 5 658 ? 118.151 136.800 134.407 1.00 139.72 ? 120 TRP R N   1 
ATOM   7645 C CA  . TRP E 5 658 ? 119.154 137.087 133.387 1.00 141.09 ? 120 TRP R CA  1 
ATOM   7646 C C   . TRP E 5 658 ? 119.833 138.424 133.626 1.00 139.98 ? 120 TRP R C   1 
ATOM   7647 O O   . TRP E 5 658 ? 120.960 138.618 133.159 1.00 139.40 ? 120 TRP R O   1 
ATOM   7648 C CB  . TRP E 5 658 ? 118.622 137.083 131.948 1.00 145.07 ? 120 TRP R CB  1 
ATOM   7649 C CG  . TRP E 5 658 ? 117.198 137.416 131.685 1.00 146.91 ? 120 TRP R CG  1 
ATOM   7650 C CD1 . TRP E 5 658 ? 116.678 138.660 131.479 1.00 144.60 ? 120 TRP R CD1 1 
ATOM   7651 C CD2 . TRP E 5 658 ? 116.141 136.492 131.413 1.00 148.15 ? 120 TRP R CD2 1 
ATOM   7652 N NE1 . TRP E 5 658 ? 115.342 138.571 131.180 1.00 147.07 ? 120 TRP R NE1 1 
ATOM   7653 C CE2 . TRP E 5 658 ? 114.986 137.249 131.133 1.00 148.58 ? 120 TRP R CE2 1 
ATOM   7654 C CE3 . TRP E 5 658 ? 116.044 135.098 131.434 1.00 144.71 ? 120 TRP R CE3 1 
ATOM   7655 C CZ2 . TRP E 5 658 ? 113.754 136.659 130.865 1.00 146.13 ? 120 TRP R CZ2 1 
ATOM   7656 C CZ3 . TRP E 5 658 ? 114.822 134.515 131.162 1.00 142.51 ? 120 TRP R CZ3 1 
ATOM   7657 C CH2 . TRP E 5 658 ? 113.694 135.294 130.877 1.00 143.95 ? 120 TRP R CH2 1 
ATOM   7658 N N   . ARG E 5 659 ? 119.196 139.347 134.350 1.00 136.69 ? 121 ARG R N   1 
ATOM   7659 C CA  . ARG E 5 659 ? 119.933 140.551 134.723 1.00 139.55 ? 121 ARG R CA  1 
ATOM   7660 C C   . ARG E 5 659 ? 121.052 140.252 135.719 1.00 138.44 ? 121 ARG R C   1 
ATOM   7661 O O   . ARG E 5 659 ? 122.114 140.882 135.664 1.00 140.05 ? 121 ARG R O   1 
ATOM   7662 C CB  . ARG E 5 659 ? 118.980 141.625 135.242 1.00 139.92 ? 121 ARG R CB  1 
ATOM   7663 C CG  . ARG E 5 659 ? 118.286 142.351 134.101 1.00 140.37 ? 121 ARG R CG  1 
ATOM   7664 C CD  . ARG E 5 659 ? 119.274 142.503 132.938 1.00 139.70 ? 121 ARG R CD  1 
ATOM   7665 N NE  . ARG E 5 659 ? 118.633 142.767 131.657 1.00 138.13 ? 121 ARG R NE  1 
ATOM   7666 C CZ  . ARG E 5 659 ? 119.257 142.745 130.488 1.00 138.13 ? 121 ARG R CZ  1 
ATOM   7667 N NH1 . ARG E 5 659 ? 120.550 142.487 130.400 1.00 138.42 ? 121 ARG R NH1 1 
ATOM   7668 N NH2 . ARG E 5 659 ? 118.564 142.985 129.379 1.00 138.68 ? 121 ARG R NH2 1 
ATOM   7669 N N   . ILE E 5 660 ? 120.845 139.303 136.636 1.00 128.99 ? 122 ILE R N   1 
ATOM   7670 C CA  . ILE E 5 660 ? 121.956 138.900 137.502 1.00 130.67 ? 122 ILE R CA  1 
ATOM   7671 C C   . ILE E 5 660 ? 123.049 138.204 136.698 1.00 131.87 ? 122 ILE R C   1 
ATOM   7672 O O   . ILE E 5 660 ? 124.239 138.482 136.887 1.00 130.20 ? 122 ILE R O   1 
ATOM   7673 C CB  . ILE E 5 660 ? 121.502 138.027 138.691 1.00 129.90 ? 122 ILE R CB  1 
ATOM   7674 C CG1 . ILE E 5 660 ? 120.083 138.342 139.157 1.00 127.70 ? 122 ILE R CG1 1 
ATOM   7675 C CG2 . ILE E 5 660 ? 122.477 138.170 139.850 1.00 131.02 ? 122 ILE R CG2 1 
ATOM   7676 C CD1 . ILE E 5 660 ? 119.871 139.798 139.559 1.00 128.72 ? 122 ILE R CD1 1 
ATOM   7677 N N   . LEU E 5 661 ? 122.677 137.283 135.803 1.00 122.70 ? 123 LEU R N   1 
ATOM   7678 C CA  . LEU E 5 661 ? 123.712 136.607 135.015 1.00 119.59 ? 123 LEU R CA  1 
ATOM   7679 C C   . LEU E 5 661 ? 124.498 137.585 134.146 1.00 117.81 ? 123 LEU R C   1 
ATOM   7680 O O   . LEU E 5 661 ? 125.722 137.463 134.023 1.00 114.97 ? 123 LEU R O   1 
ATOM   7681 C CB  . LEU E 5 661 ? 123.156 135.466 134.154 1.00 117.18 ? 123 LEU R CB  1 
ATOM   7682 C CG  . LEU E 5 661 ? 122.414 134.218 134.661 1.00 121.21 ? 123 LEU R CG  1 
ATOM   7683 C CD1 . LEU E 5 661 ? 123.286 133.470 135.671 1.00 121.68 ? 123 LEU R CD1 1 
ATOM   7684 C CD2 . LEU E 5 661 ? 121.030 134.430 135.203 1.00 120.33 ? 123 LEU R CD2 1 
ATOM   7685 N N   . ARG E 5 662 ? 123.822 138.554 133.529 1.00 128.79 ? 124 ARG R N   1 
ATOM   7686 C CA  . ARG E 5 662 ? 124.537 139.513 132.691 1.00 130.07 ? 124 ARG R CA  1 
ATOM   7687 C C   . ARG E 5 662 ? 125.405 140.449 133.523 1.00 134.19 ? 124 ARG R C   1 
ATOM   7688 O O   . ARG E 5 662 ? 126.583 140.660 133.210 1.00 138.81 ? 124 ARG R O   1 
ATOM   7689 C CB  . ARG E 5 662 ? 123.553 140.311 131.836 1.00 133.31 ? 124 ARG R CB  1 
ATOM   7690 C CG  . ARG E 5 662 ? 123.161 139.612 130.549 1.00 135.64 ? 124 ARG R CG  1 
ATOM   7691 C CD  . ARG E 5 662 ? 122.999 140.619 129.422 1.00 133.83 ? 124 ARG R CD  1 
ATOM   7692 N NE  . ARG E 5 662 ? 124.175 141.470 129.278 1.00 133.76 ? 124 ARG R NE  1 
ATOM   7693 C CZ  . ARG E 5 662 ? 125.327 141.084 128.745 1.00 133.85 ? 124 ARG R CZ  1 
ATOM   7694 N NH1 . ARG E 5 662 ? 125.498 139.857 128.281 1.00 133.76 ? 124 ARG R NH1 1 
ATOM   7695 N NH2 . ARG E 5 662 ? 126.332 141.951 128.675 1.00 132.76 ? 124 ARG R NH2 1 
ATOM   7696 N N   . LEU E 5 663 ? 124.846 141.021 134.589 1.00 132.68 ? 125 LEU R N   1 
ATOM   7697 C CA  . LEU E 5 663 ? 125.535 142.031 135.381 1.00 130.90 ? 125 LEU R CA  1 
ATOM   7698 C C   . LEU E 5 663 ? 126.212 141.452 136.618 1.00 127.65 ? 125 LEU R C   1 
ATOM   7699 O O   . LEU E 5 663 ? 126.403 142.171 137.603 1.00 129.56 ? 125 LEU R O   1 
ATOM   7700 C CB  . LEU E 5 663 ? 124.560 143.138 135.788 1.00 130.95 ? 125 LEU R CB  1 
ATOM   7701 C CG  . LEU E 5 663 ? 123.747 143.781 134.664 1.00 129.86 ? 125 LEU R CG  1 
ATOM   7702 C CD1 . LEU E 5 663 ? 122.808 144.839 135.221 1.00 128.37 ? 125 LEU R CD1 1 
ATOM   7703 C CD2 . LEU E 5 663 ? 124.664 144.376 133.606 1.00 128.40 ? 125 LEU R CD2 1 
ATOM   7704 N N   . PHE E 5 664 ? 126.575 140.171 136.588 1.00 104.23 ? 126 PHE R N   1 
ATOM   7705 C CA  . PHE E 5 664 ? 127.196 139.559 137.760 1.00 107.77 ? 126 PHE R CA  1 
ATOM   7706 C C   . PHE E 5 664 ? 128.516 140.206 138.170 1.00 108.08 ? 126 PHE R C   1 
ATOM   7707 O O   . PHE E 5 664 ? 128.729 140.372 139.384 1.00 107.04 ? 126 PHE R O   1 
ATOM   7708 C CB  . PHE E 5 664 ? 127.373 138.054 137.534 1.00 107.25 ? 126 PHE R CB  1 
ATOM   7709 C CG  . PHE E 5 664 ? 127.135 137.236 138.766 1.00 103.48 ? 126 PHE R CG  1 
ATOM   7710 C CD1 . PHE E 5 664 ? 125.849 136.980 139.203 1.00 104.86 ? 126 PHE R CD1 1 
ATOM   7711 C CD2 . PHE E 5 664 ? 128.196 136.741 139.500 1.00 104.44 ? 126 PHE R CD2 1 
ATOM   7712 C CE1 . PHE E 5 664 ? 125.626 136.236 140.340 1.00 107.78 ? 126 PHE R CE1 1 
ATOM   7713 C CE2 . PHE E 5 664 ? 127.979 135.996 140.637 1.00 106.67 ? 126 PHE R CE2 1 
ATOM   7714 C CZ  . PHE E 5 664 ? 126.692 135.744 141.058 1.00 107.08 ? 126 PHE R CZ  1 
ATOM   7715 N N   . PRO E 5 665 ? 129.441 140.552 137.266 1.00 100.94 ? 127 PRO R N   1 
ATOM   7716 C CA  . PRO E 5 665 ? 130.626 141.302 137.717 1.00 100.96 ? 127 PRO R CA  1 
ATOM   7717 C C   . PRO E 5 665 ? 130.276 142.623 138.377 1.00 105.13 ? 127 PRO R C   1 
ATOM   7718 O O   . PRO E 5 665 ? 130.970 143.050 139.311 1.00 107.64 ? 127 PRO R O   1 
ATOM   7719 C CB  . PRO E 5 665 ? 131.427 141.504 136.424 1.00 101.05 ? 127 PRO R CB  1 
ATOM   7720 C CG  . PRO E 5 665 ? 130.983 140.403 135.534 1.00 99.50  ? 127 PRO R CG  1 
ATOM   7721 C CD  . PRO E 5 665 ? 129.532 140.206 135.837 1.00 97.61  ? 127 PRO R CD  1 
ATOM   7722 N N   . TRP E 5 666 ? 129.207 143.283 137.927 1.00 112.90 ? 128 TRP R N   1 
ATOM   7723 C CA  . TRP E 5 666 ? 128.744 144.476 138.624 1.00 111.43 ? 128 TRP R CA  1 
ATOM   7724 C C   . TRP E 5 666 ? 128.221 144.140 140.013 1.00 111.74 ? 128 TRP R C   1 
ATOM   7725 O O   . TRP E 5 666 ? 128.378 144.939 140.939 1.00 109.54 ? 128 TRP R O   1 
ATOM   7726 C CB  . TRP E 5 666 ? 127.674 145.192 137.801 1.00 111.29 ? 128 TRP R CB  1 
ATOM   7727 C CG  . TRP E 5 666 ? 128.153 145.581 136.442 1.00 112.33 ? 128 TRP R CG  1 
ATOM   7728 C CD1 . TRP E 5 666 ? 127.763 145.046 135.251 1.00 113.83 ? 128 TRP R CD1 1 
ATOM   7729 C CD2 . TRP E 5 666 ? 129.130 146.580 136.133 1.00 106.64 ? 128 TRP R CD2 1 
ATOM   7730 N NE1 . TRP E 5 666 ? 128.430 145.657 134.217 1.00 113.46 ? 128 TRP R NE1 1 
ATOM   7731 C CE2 . TRP E 5 666 ? 129.276 146.602 134.733 1.00 107.74 ? 128 TRP R CE2 1 
ATOM   7732 C CE3 . TRP E 5 666 ? 129.892 147.461 136.904 1.00 107.98 ? 128 TRP R CE3 1 
ATOM   7733 C CZ2 . TRP E 5 666 ? 130.152 147.469 134.088 1.00 108.74 ? 128 TRP R CZ2 1 
ATOM   7734 C CZ3 . TRP E 5 666 ? 130.762 148.321 136.263 1.00 111.85 ? 128 TRP R CZ3 1 
ATOM   7735 C CH2 . TRP E 5 666 ? 130.885 148.319 134.869 1.00 111.97 ? 128 TRP R CH2 1 
ATOM   7736 N N   . ILE E 5 667 ? 127.619 142.962 140.187 1.00 102.18 ? 129 ILE R N   1 
ATOM   7737 C CA  . ILE E 5 667 ? 127.214 142.539 141.523 1.00 98.34  ? 129 ILE R CA  1 
ATOM   7738 C C   . ILE E 5 667 ? 128.437 142.287 142.397 1.00 103.09 ? 129 ILE R C   1 
ATOM   7739 O O   . ILE E 5 667 ? 128.425 142.571 143.599 1.00 107.40 ? 129 ILE R O   1 
ATOM   7740 C CB  . ILE E 5 667 ? 126.304 141.302 141.446 1.00 97.84  ? 129 ILE R CB  1 
ATOM   7741 C CG1 . ILE E 5 667 ? 125.174 141.535 140.447 1.00 103.21 ? 129 ILE R CG1 1 
ATOM   7742 C CG2 . ILE E 5 667 ? 125.723 140.989 142.810 1.00 99.73  ? 129 ILE R CG2 1 
ATOM   7743 C CD1 . ILE E 5 667 ? 124.204 142.612 140.872 1.00 102.27 ? 129 ILE R CD1 1 
ATOM   7744 N N   . LEU E 5 668 ? 129.508 141.745 141.814 1.00 100.28 ? 130 LEU R N   1 
ATOM   7745 C CA  . LEU E 5 668 ? 130.746 141.562 142.569 1.00 101.82 ? 130 LEU R CA  1 
ATOM   7746 C C   . LEU E 5 668 ? 131.331 142.902 143.005 1.00 104.74 ? 130 LEU R C   1 
ATOM   7747 O O   . LEU E 5 668 ? 131.770 143.060 144.153 1.00 104.20 ? 130 LEU R O   1 
ATOM   7748 C CB  . LEU E 5 668 ? 131.761 140.788 141.732 1.00 96.76  ? 130 LEU R CB  1 
ATOM   7749 C CG  . LEU E 5 668 ? 131.857 139.289 141.998 1.00 95.56  ? 130 LEU R CG  1 
ATOM   7750 C CD1 . LEU E 5 668 ? 130.628 138.580 141.466 1.00 100.08 ? 130 LEU R CD1 1 
ATOM   7751 C CD2 . LEU E 5 668 ? 133.119 138.722 141.377 1.00 98.62  ? 130 LEU R CD2 1 
ATOM   7752 N N   . LEU E 5 669 ? 131.351 143.877 142.095 1.00 110.92 ? 131 LEU R N   1 
ATOM   7753 C CA  . LEU E 5 669 ? 131.824 145.210 142.453 1.00 111.73 ? 131 LEU R CA  1 
ATOM   7754 C C   . LEU E 5 669 ? 130.934 145.834 143.521 1.00 113.79 ? 131 LEU R C   1 
ATOM   7755 O O   . LEU E 5 669 ? 131.422 146.522 144.426 1.00 116.04 ? 131 LEU R O   1 
ATOM   7756 C CB  . LEU E 5 669 ? 131.884 146.098 141.210 1.00 114.28 ? 131 LEU R CB  1 
ATOM   7757 C CG  . LEU E 5 669 ? 132.028 147.603 141.440 1.00 115.16 ? 131 LEU R CG  1 
ATOM   7758 C CD1 . LEU E 5 669 ? 133.383 147.926 142.052 1.00 113.39 ? 131 LEU R CD1 1 
ATOM   7759 C CD2 . LEU E 5 669 ? 131.828 148.365 140.139 1.00 111.82 ? 131 LEU R CD2 1 
ATOM   7760 N N   . GLY E 5 670 ? 129.622 145.608 143.427 1.00 113.55 ? 132 GLY R N   1 
ATOM   7761 C CA  . GLY E 5 670 ? 128.720 146.087 144.460 1.00 115.32 ? 132 GLY R CA  1 
ATOM   7762 C C   . GLY E 5 670 ? 128.998 145.454 145.808 1.00 114.36 ? 132 GLY R C   1 
ATOM   7763 O O   . GLY E 5 670 ? 128.927 146.118 146.843 1.00 119.84 ? 132 GLY R O   1 
ATOM   7764 N N   . CYS E 5 671 ? 129.314 144.159 145.814 1.00 105.15 ? 133 CYS R N   1 
ATOM   7765 C CA  . CYS E 5 671 ? 129.686 143.496 147.058 1.00 110.40 ? 133 CYS R CA  1 
ATOM   7766 C C   . CYS E 5 671 ? 130.958 144.099 147.638 1.00 115.07 ? 133 CYS R C   1 
ATOM   7767 O O   . CYS E 5 671 ? 131.049 144.332 148.848 1.00 117.20 ? 133 CYS R O   1 
ATOM   7768 C CB  . CYS E 5 671 ? 129.856 141.996 146.827 1.00 111.19 ? 133 CYS R CB  1 
ATOM   7769 S SG  . CYS E 5 671 ? 128.305 141.107 146.578 1.00 122.48 ? 133 CYS R SG  1 
ATOM   7770 N N   . LEU E 5 672 ? 131.945 144.376 146.786 1.00 103.02 ? 134 LEU R N   1 
ATOM   7771 C CA  . LEU E 5 672 ? 133.178 144.988 147.277 1.00 97.67  ? 134 LEU R CA  1 
ATOM   7772 C C   . LEU E 5 672 ? 132.916 146.373 147.861 1.00 90.32  ? 134 LEU R C   1 
ATOM   7773 O O   . LEU E 5 672 ? 133.438 146.717 148.931 1.00 92.85  ? 134 LEU R O   1 
ATOM   7774 C CB  . LEU E 5 672 ? 134.210 145.066 146.154 1.00 96.76  ? 134 LEU R CB  1 
ATOM   7775 C CG  . LEU E 5 672 ? 135.565 145.641 146.559 1.00 93.51  ? 134 LEU R CG  1 
ATOM   7776 C CD1 . LEU E 5 672 ? 136.177 144.810 147.669 1.00 94.25  ? 134 LEU R CD1 1 
ATOM   7777 C CD2 . LEU E 5 672 ? 136.497 145.707 145.364 1.00 96.72  ? 134 LEU R CD2 1 
ATOM   7778 N N   . MET E 5 673 ? 132.099 147.181 147.182 1.00 102.80 ? 135 MET R N   1 
ATOM   7779 C CA  . MET E 5 673 ? 131.879 148.541 147.663 1.00 106.09 ? 135 MET R CA  1 
ATOM   7780 C C   . MET E 5 673 ? 131.014 148.554 148.919 1.00 107.48 ? 135 MET R C   1 
ATOM   7781 O O   . MET E 5 673 ? 131.216 149.395 149.801 1.00 108.21 ? 135 MET R O   1 
ATOM   7782 C CB  . MET E 5 673 ? 131.265 149.416 146.567 1.00 107.21 ? 135 MET R CB  1 
ATOM   7783 C CG  . MET E 5 673 ? 129.934 148.946 146.028 1.00 109.26 ? 135 MET R CG  1 
ATOM   7784 S SD  . MET E 5 673 ? 128.535 149.765 146.816 1.00 119.01 ? 135 MET R SD  1 
ATOM   7785 C CE  . MET E 5 673 ? 127.216 149.358 145.675 1.00 106.79 ? 135 MET R CE  1 
ATOM   7786 N N   . ILE E 5 674 ? 130.051 147.632 149.032 1.00 101.21 ? 136 ILE R N   1 
ATOM   7787 C CA  . ILE E 5 674 ? 129.284 147.566 150.271 1.00 101.67 ? 136 ILE R CA  1 
ATOM   7788 C C   . ILE E 5 674 ? 130.162 147.046 151.399 1.00 103.51 ? 136 ILE R C   1 
ATOM   7789 O O   . ILE E 5 674 ? 129.998 147.451 152.555 1.00 107.70 ? 136 ILE R O   1 
ATOM   7790 C CB  . ILE E 5 674 ? 128.002 146.726 150.106 1.00 101.50 ? 136 ILE R CB  1 
ATOM   7791 C CG1 . ILE E 5 674 ? 127.138 146.822 151.363 1.00 105.39 ? 136 ILE R CG1 1 
ATOM   7792 C CG2 . ILE E 5 674 ? 128.317 145.274 149.852 1.00 102.57 ? 136 ILE R CG2 1 
ATOM   7793 C CD1 . ILE E 5 674 ? 125.657 146.871 151.081 1.00 106.42 ? 136 ILE R CD1 1 
ATOM   7794 N N   . THR E 5 675 ? 131.125 146.174 151.090 1.00 103.47 ? 137 THR R N   1 
ATOM   7795 C CA  . THR E 5 675 ? 132.096 145.763 152.096 1.00 106.10 ? 137 THR R CA  1 
ATOM   7796 C C   . THR E 5 675 ? 132.890 146.961 152.600 1.00 106.78 ? 137 THR R C   1 
ATOM   7797 O O   . THR E 5 675 ? 133.076 147.134 153.809 1.00 107.55 ? 137 THR R O   1 
ATOM   7798 C CB  . THR E 5 675 ? 133.034 144.703 151.517 1.00 108.79 ? 137 THR R CB  1 
ATOM   7799 O OG1 . THR E 5 675 ? 132.263 143.636 150.950 1.00 109.24 ? 137 THR R OG1 1 
ATOM   7800 C CG2 . THR E 5 675 ? 133.941 144.143 152.598 1.00 106.02 ? 137 THR R CG2 1 
ATOM   7801 N N   . CYS E 5 676 ? 133.350 147.813 151.681 1.00 107.38 ? 138 CYS R N   1 
ATOM   7802 C CA  . CYS E 5 676 ? 134.094 149.005 152.083 1.00 103.72 ? 138 CYS R CA  1 
ATOM   7803 C C   . CYS E 5 676 ? 133.227 149.944 152.918 1.00 105.36 ? 138 CYS R C   1 
ATOM   7804 O O   . CYS E 5 676 ? 133.662 150.456 153.960 1.00 108.46 ? 138 CYS R O   1 
ATOM   7805 C CB  . CYS E 5 676 ? 134.632 149.729 150.849 1.00 104.84 ? 138 CYS R CB  1 
ATOM   7806 S SG  . CYS E 5 676 ? 135.861 148.800 149.905 1.00 116.94 ? 138 CYS R SG  1 
ATOM   7807 N N   . VAL E 5 677 ? 131.990 150.176 152.474 1.00 103.24 ? 139 VAL R N   1 
ATOM   7808 C CA  . VAL E 5 677 ? 131.096 151.094 153.175 1.00 105.13 ? 139 VAL R CA  1 
ATOM   7809 C C   . VAL E 5 677 ? 130.804 150.585 154.579 1.00 103.80 ? 139 VAL R C   1 
ATOM   7810 O O   . VAL E 5 677 ? 130.800 151.353 155.549 1.00 109.44 ? 139 VAL R O   1 
ATOM   7811 C CB  . VAL E 5 677 ? 129.801 151.296 152.366 1.00 105.38 ? 139 VAL R CB  1 
ATOM   7812 C CG1 . VAL E 5 677 ? 128.708 151.888 153.241 1.00 103.67 ? 139 VAL R CG1 1 
ATOM   7813 C CG2 . VAL E 5 677 ? 130.064 152.183 151.162 1.00 106.81 ? 139 VAL R CG2 1 
ATOM   7814 N N   . THR E 5 678 ? 130.563 149.282 154.712 1.00 100.77 ? 140 THR R N   1 
ATOM   7815 C CA  . THR E 5 678 ? 130.247 148.708 156.011 1.00 100.03 ? 140 THR R CA  1 
ATOM   7816 C C   . THR E 5 678 ? 131.480 148.635 156.908 1.00 101.05 ? 140 THR R C   1 
ATOM   7817 O O   . THR E 5 678 ? 131.359 148.738 158.135 1.00 105.67 ? 140 THR R O   1 
ATOM   7818 C CB  . THR E 5 678 ? 129.612 147.330 155.799 1.00 107.97 ? 140 THR R CB  1 
ATOM   7819 O OG1 . THR E 5 678 ? 128.221 147.492 155.493 1.00 112.94 ? 140 THR R OG1 1 
ATOM   7820 C CG2 . THR E 5 678 ? 129.741 146.462 157.020 1.00 106.77 ? 140 THR R CG2 1 
ATOM   7821 N N   . ILE E 5 679 ? 132.672 148.492 156.326 1.00 94.96  ? 141 ILE R N   1 
ATOM   7822 C CA  . ILE E 5 679 ? 133.880 148.433 157.141 1.00 96.45  ? 141 ILE R CA  1 
ATOM   7823 C C   . ILE E 5 679 ? 134.373 149.812 157.554 1.00 101.40 ? 141 ILE R C   1 
ATOM   7824 O O   . ILE E 5 679 ? 135.193 149.913 158.476 1.00 101.28 ? 141 ILE R O   1 
ATOM   7825 C CB  . ILE E 5 679 ? 135.002 147.680 156.407 1.00 97.35  ? 141 ILE R CB  1 
ATOM   7826 C CG1 . ILE E 5 679 ? 135.914 146.990 157.416 1.00 98.76  ? 141 ILE R CG1 1 
ATOM   7827 C CG2 . ILE E 5 679 ? 135.808 148.624 155.533 1.00 98.77  ? 141 ILE R CG2 1 
ATOM   7828 C CD1 . ILE E 5 679 ? 135.175 146.110 158.392 1.00 98.95  ? 141 ILE R CD1 1 
ATOM   7829 N N   . ILE E 5 680 ? 133.914 150.877 156.889 1.00 109.09 ? 142 ILE R N   1 
ATOM   7830 C CA  . ILE E 5 680 ? 134.310 152.228 157.297 1.00 102.76 ? 142 ILE R CA  1 
ATOM   7831 C C   . ILE E 5 680 ? 134.014 152.507 158.770 1.00 98.71  ? 142 ILE R C   1 
ATOM   7832 O O   . ILE E 5 680 ? 134.885 153.067 159.454 1.00 103.61 ? 142 ILE R O   1 
ATOM   7833 C CB  . ILE E 5 680 ? 133.682 153.271 156.351 1.00 104.59 ? 142 ILE R CB  1 
ATOM   7834 C CG1 . ILE E 5 680 ? 134.552 153.447 155.106 1.00 104.02 ? 142 ILE R CG1 1 
ATOM   7835 C CG2 . ILE E 5 680 ? 133.486 154.599 157.063 1.00 104.59 ? 142 ILE R CG2 1 
ATOM   7836 C CD1 . ILE E 5 680 ? 133.936 154.344 154.056 1.00 103.69 ? 142 ILE R CD1 1 
ATOM   7837 N N   . PRO E 5 681 ? 132.838 152.169 159.319 1.00 90.07  ? 143 PRO R N   1 
ATOM   7838 C CA  . PRO E 5 681 ? 132.648 152.348 160.769 1.00 93.40  ? 143 PRO R CA  1 
ATOM   7839 C C   . PRO E 5 681 ? 133.664 151.600 161.611 1.00 94.64  ? 143 PRO R C   1 
ATOM   7840 O O   . PRO E 5 681 ? 134.107 152.117 162.643 1.00 101.36 ? 143 PRO R O   1 
ATOM   7841 C CB  . PRO E 5 681 ? 131.225 151.825 160.999 1.00 93.33  ? 143 PRO R CB  1 
ATOM   7842 C CG  . PRO E 5 681 ? 130.540 152.062 159.717 1.00 93.63  ? 143 PRO R CG  1 
ATOM   7843 C CD  . PRO E 5 681 ? 131.570 151.809 158.656 1.00 93.72  ? 143 PRO R CD  1 
ATOM   7844 N N   . SER E 5 682 ? 134.054 150.394 161.199 1.00 102.91 ? 144 SER R N   1 
ATOM   7845 C CA  . SER E 5 682 ? 135.094 149.677 161.928 1.00 105.90 ? 144 SER R CA  1 
ATOM   7846 C C   . SER E 5 682 ? 136.414 150.434 161.877 1.00 106.19 ? 144 SER R C   1 
ATOM   7847 O O   . SER E 5 682 ? 137.142 150.501 162.875 1.00 106.93 ? 144 SER R O   1 
ATOM   7848 C CB  . SER E 5 682 ? 135.255 148.268 161.360 1.00 109.80 ? 144 SER R CB  1 
ATOM   7849 O OG  . SER E 5 682 ? 136.230 147.535 162.081 1.00 111.18 ? 144 SER R OG  1 
ATOM   7850 N N   . ALA E 5 683 ? 136.740 151.011 160.718 1.00 109.83 ? 145 ALA R N   1 
ATOM   7851 C CA  . ALA E 5 683 ? 137.971 151.782 160.596 1.00 110.93 ? 145 ALA R CA  1 
ATOM   7852 C C   . ALA E 5 683 ? 137.956 153.002 161.508 1.00 113.75 ? 145 ALA R C   1 
ATOM   7853 O O   . ALA E 5 683 ? 138.952 153.295 162.179 1.00 111.11 ? 145 ALA R O   1 
ATOM   7854 C CB  . ALA E 5 683 ? 138.185 152.202 159.142 1.00 110.04 ? 145 ALA R CB  1 
ATOM   7855 N N   . ILE E 5 684 ? 136.835 153.727 161.551 1.00 121.11 ? 146 ILE R N   1 
ATOM   7856 C CA  . ILE E 5 684 ? 136.786 154.915 162.399 1.00 117.53 ? 146 ILE R CA  1 
ATOM   7857 C C   . ILE E 5 684 ? 136.806 154.520 163.872 1.00 114.95 ? 146 ILE R C   1 
ATOM   7858 O O   . ILE E 5 684 ? 137.381 155.226 164.708 1.00 118.58 ? 146 ILE R O   1 
ATOM   7859 C CB  . ILE E 5 684 ? 135.581 155.810 162.025 1.00 116.59 ? 146 ILE R CB  1 
ATOM   7860 C CG1 . ILE E 5 684 ? 134.218 155.200 162.384 1.00 116.36 ? 146 ILE R CG1 1 
ATOM   7861 C CG2 . ILE E 5 684 ? 135.622 156.158 160.543 1.00 116.66 ? 146 ILE R CG2 1 
ATOM   7862 C CD1 . ILE E 5 684 ? 133.754 155.404 163.822 1.00 114.66 ? 146 ILE R CD1 1 
ATOM   7863 N N   . GLY E 5 685 ? 136.196 153.382 164.214 1.00 118.44 ? 147 GLY R N   1 
ATOM   7864 C CA  . GLY E 5 685 ? 136.287 152.896 165.581 1.00 121.05 ? 147 GLY R CA  1 
ATOM   7865 C C   . GLY E 5 685 ? 137.710 152.552 165.976 1.00 124.09 ? 147 GLY R C   1 
ATOM   7866 O O   . GLY E 5 685 ? 138.157 152.877 167.079 1.00 126.75 ? 147 GLY R O   1 
ATOM   7867 N N   . ASN E 5 686 ? 138.445 151.896 165.076 1.00 123.90 ? 148 ASN R N   1 
ATOM   7868 C CA  . ASN E 5 686 ? 139.849 151.606 165.345 1.00 124.69 ? 148 ASN R CA  1 
ATOM   7869 C C   . ASN E 5 686 ? 140.655 152.891 165.479 1.00 127.91 ? 148 ASN R C   1 
ATOM   7870 O O   . ASN E 5 686 ? 141.554 152.986 166.323 1.00 128.13 ? 148 ASN R O   1 
ATOM   7871 C CB  . ASN E 5 686 ? 140.427 150.723 164.243 1.00 124.34 ? 148 ASN R CB  1 
ATOM   7872 C CG  . ASN E 5 686 ? 141.904 150.454 164.430 1.00 126.48 ? 148 ASN R CG  1 
ATOM   7873 O OD1 . ASN E 5 686 ? 142.307 149.768 165.369 1.00 125.75 ? 148 ASN R OD1 1 
ATOM   7874 N ND2 . ASN E 5 686 ? 142.723 150.997 163.538 1.00 126.91 ? 148 ASN R ND2 1 
ATOM   7875 N N   . TYR E 5 687 ? 140.347 153.893 164.654 1.00 138.37 ? 149 TYR R N   1 
ATOM   7876 C CA  . TYR E 5 687 ? 141.058 155.164 164.744 1.00 138.47 ? 149 TYR R CA  1 
ATOM   7877 C C   . TYR E 5 687 ? 140.811 155.839 166.088 1.00 136.64 ? 149 TYR R C   1 
ATOM   7878 O O   . TYR E 5 687 ? 141.744 156.334 166.727 1.00 133.76 ? 149 TYR R O   1 
ATOM   7879 C CB  . TYR E 5 687 ? 140.642 156.083 163.595 1.00 137.98 ? 149 TYR R CB  1 
ATOM   7880 C CG  . TYR E 5 687 ? 141.080 157.518 163.779 1.00 138.94 ? 149 TYR R CG  1 
ATOM   7881 C CD1 . TYR E 5 687 ? 142.387 157.904 163.512 1.00 140.18 ? 149 TYR R CD1 1 
ATOM   7882 C CD2 . TYR E 5 687 ? 140.187 158.488 164.218 1.00 138.47 ? 149 TYR R CD2 1 
ATOM   7883 C CE1 . TYR E 5 687 ? 142.793 159.214 163.679 1.00 141.31 ? 149 TYR R CE1 1 
ATOM   7884 C CE2 . TYR E 5 687 ? 140.585 159.800 164.388 1.00 140.80 ? 149 TYR R CE2 1 
ATOM   7885 C CZ  . TYR E 5 687 ? 141.889 160.158 164.116 1.00 140.92 ? 149 TYR R CZ  1 
ATOM   7886 O OH  . TYR E 5 687 ? 142.289 161.464 164.283 1.00 136.83 ? 149 TYR R OH  1 
ATOM   7887 N N   . ILE E 5 688 ? 139.555 155.867 166.538 1.00 134.23 ? 150 ILE R N   1 
ATOM   7888 C CA  . ILE E 5 688 ? 139.275 156.498 167.825 1.00 133.22 ? 150 ILE R CA  1 
ATOM   7889 C C   . ILE E 5 688 ? 139.891 155.697 168.967 1.00 131.76 ? 150 ILE R C   1 
ATOM   7890 O O   . ILE E 5 688 ? 140.356 156.277 169.956 1.00 133.57 ? 150 ILE R O   1 
ATOM   7891 C CB  . ILE E 5 688 ? 137.756 156.750 167.996 1.00 133.72 ? 150 ILE R CB  1 
ATOM   7892 C CG1 . ILE E 5 688 ? 136.930 155.479 168.274 1.00 132.93 ? 150 ILE R CG1 1 
ATOM   7893 C CG2 . ILE E 5 688 ? 137.204 157.524 166.804 1.00 132.45 ? 150 ILE R CG2 1 
ATOM   7894 C CD1 . ILE E 5 688 ? 136.921 154.972 169.714 1.00 129.05 ? 150 ILE R CD1 1 
ATOM   7895 N N   . GLN E 5 689 ? 139.931 154.366 168.855 1.00 136.38 ? 151 GLN R N   1 
ATOM   7896 C CA  . GLN E 5 689 ? 140.512 153.579 169.937 1.00 139.13 ? 151 GLN R CA  1 
ATOM   7897 C C   . GLN E 5 689 ? 142.029 153.716 169.980 1.00 139.67 ? 151 GLN R C   1 
ATOM   7898 O O   . GLN E 5 689 ? 142.625 153.617 171.058 1.00 139.25 ? 151 GLN R O   1 
ATOM   7899 C CB  . GLN E 5 689 ? 140.099 152.109 169.817 1.00 139.53 ? 151 GLN R CB  1 
ATOM   7900 C CG  . GLN E 5 689 ? 140.928 151.274 168.854 1.00 139.91 ? 151 GLN R CG  1 
ATOM   7901 C CD  . GLN E 5 689 ? 142.016 150.482 169.555 1.00 141.27 ? 151 GLN R CD  1 
ATOM   7902 O OE1 . GLN E 5 689 ? 142.168 150.558 170.774 1.00 141.14 ? 151 GLN R OE1 1 
ATOM   7903 N NE2 . GLN E 5 689 ? 142.781 149.717 168.784 1.00 141.45 ? 151 GLN R NE2 1 
ATOM   7904 N N   . ILE E 5 690 ? 142.675 153.943 168.832 1.00 136.49 ? 152 ILE R N   1 
ATOM   7905 C CA  . ILE E 5 690 ? 144.120 154.145 168.850 1.00 136.03 ? 152 ILE R CA  1 
ATOM   7906 C C   . ILE E 5 690 ? 144.453 155.571 169.278 1.00 137.91 ? 152 ILE R C   1 
ATOM   7907 O O   . ILE E 5 690 ? 145.509 155.824 169.869 1.00 138.28 ? 152 ILE R O   1 
ATOM   7908 C CB  . ILE E 5 690 ? 144.743 153.784 167.487 1.00 134.95 ? 152 ILE R CB  1 
ATOM   7909 C CG1 . ILE E 5 690 ? 146.267 153.722 167.597 1.00 135.85 ? 152 ILE R CG1 1 
ATOM   7910 C CG2 . ILE E 5 690 ? 144.352 154.780 166.416 1.00 134.24 ? 152 ILE R CG2 1 
ATOM   7911 C CD1 . ILE E 5 690 ? 146.762 152.723 168.616 1.00 134.76 ? 152 ILE R CD1 1 
ATOM   7912 N N   . GLN E 5 691 ? 143.560 156.526 168.992 1.00 141.48 ? 153 GLN R N   1 
ATOM   7913 C CA  . GLN E 5 691 ? 143.728 157.870 169.537 1.00 140.72 ? 153 GLN R CA  1 
ATOM   7914 C C   . GLN E 5 691 ? 143.587 157.868 171.053 1.00 139.43 ? 153 GLN R C   1 
ATOM   7915 O O   . GLN E 5 691 ? 144.327 158.569 171.754 1.00 139.52 ? 153 GLN R O   1 
ATOM   7916 C CB  . GLN E 5 691 ? 142.721 158.833 168.908 1.00 140.71 ? 153 GLN R CB  1 
ATOM   7917 C CG  . GLN E 5 691 ? 142.970 159.121 167.439 1.00 141.09 ? 153 GLN R CG  1 
ATOM   7918 C CD  . GLN E 5 691 ? 144.440 159.317 167.128 1.00 142.01 ? 153 GLN R CD  1 
ATOM   7919 O OE1 . GLN E 5 691 ? 145.065 160.267 167.602 1.00 143.61 ? 153 GLN R OE1 1 
ATOM   7920 N NE2 . GLN E 5 691 ? 145.001 158.418 166.329 1.00 140.69 ? 153 GLN R NE2 1 
ATOM   7921 N N   . LEU E 5 692 ? 142.636 157.092 171.578 1.00 138.07 ? 154 LEU R N   1 
ATOM   7922 C CA  . LEU E 5 692 ? 142.507 156.964 173.025 1.00 138.87 ? 154 LEU R CA  1 
ATOM   7923 C C   . LEU E 5 692 ? 143.761 156.338 173.623 1.00 138.71 ? 154 LEU R C   1 
ATOM   7924 O O   . LEU E 5 692 ? 144.232 156.763 174.684 1.00 136.38 ? 154 LEU R O   1 
ATOM   7925 C CB  . LEU E 5 692 ? 141.255 156.147 173.364 1.00 138.58 ? 154 LEU R CB  1 
ATOM   7926 C CG  . LEU E 5 692 ? 140.764 155.879 174.798 1.00 138.30 ? 154 LEU R CG  1 
ATOM   7927 C CD1 . LEU E 5 692 ? 141.672 154.966 175.623 1.00 138.60 ? 154 LEU R CD1 1 
ATOM   7928 C CD2 . LEU E 5 692 ? 140.538 157.200 175.525 1.00 137.84 ? 154 LEU R CD2 1 
ATOM   7929 N N   . LEU E 5 693 ? 144.315 155.332 172.955 1.00 147.42 ? 155 LEU R N   1 
ATOM   7930 C CA  . LEU E 5 693 ? 145.540 154.689 173.409 1.00 148.11 ? 155 LEU R CA  1 
ATOM   7931 C C   . LEU E 5 693 ? 146.724 155.643 173.291 1.00 146.14 ? 155 LEU R C   1 
ATOM   7932 O O   . LEU E 5 693 ? 147.447 155.873 174.260 1.00 144.82 ? 155 LEU R O   1 
ATOM   7933 C CB  . LEU E 5 693 ? 145.806 153.412 172.609 1.00 148.09 ? 155 LEU R CB  1 
ATOM   7934 C CG  . LEU E 5 693 ? 147.015 152.571 173.027 1.00 148.69 ? 155 LEU R CG  1 
ATOM   7935 C CD1 . LEU E 5 693 ? 146.635 151.101 173.117 1.00 146.21 ? 155 LEU R CD1 1 
ATOM   7936 C CD2 . LEU E 5 693 ? 148.175 152.768 172.063 1.00 148.08 ? 155 LEU R CD2 1 
ATOM   7937 N N   . GLU E 5 709 ? 133.749 152.093 177.034 1.00 172.47 ? 171 GLU R N   1 
ATOM   7938 C CA  . GLU E 5 709 ? 132.499 152.804 177.268 1.00 173.00 ? 171 GLU R CA  1 
ATOM   7939 C C   . GLU E 5 709 ? 131.598 152.740 176.039 1.00 173.62 ? 171 GLU R C   1 
ATOM   7940 O O   . GLU E 5 709 ? 131.474 151.691 175.405 1.00 171.97 ? 171 GLU R O   1 
ATOM   7941 C CB  . GLU E 5 709 ? 132.772 154.263 177.651 1.00 172.45 ? 171 GLU R CB  1 
ATOM   7942 C CG  . GLU E 5 709 ? 133.829 154.953 176.799 1.00 172.56 ? 171 GLU R CG  1 
ATOM   7943 C CD  . GLU E 5 709 ? 135.226 154.817 177.371 1.00 172.92 ? 171 GLU R CD  1 
ATOM   7944 O OE1 . GLU E 5 709 ? 135.433 153.948 178.244 1.00 172.97 ? 171 GLU R OE1 1 
ATOM   7945 O OE2 . GLU E 5 709 ? 136.119 155.581 176.948 1.00 172.54 ? 171 GLU R OE2 1 
ATOM   7946 N N   . ASN E 5 710 ? 130.965 153.870 175.711 1.00 168.95 ? 172 ASN R N   1 
ATOM   7947 C CA  . ASN E 5 710 ? 130.105 153.921 174.534 1.00 166.37 ? 172 ASN R CA  1 
ATOM   7948 C C   . ASN E 5 710 ? 130.886 153.642 173.257 1.00 166.20 ? 172 ASN R C   1 
ATOM   7949 O O   . ASN E 5 710 ? 130.330 153.100 172.297 1.00 165.42 ? 172 ASN R O   1 
ATOM   7950 C CB  . ASN E 5 710 ? 129.411 155.280 174.447 1.00 165.95 ? 172 ASN R CB  1 
ATOM   7951 C CG  . ASN E 5 710 ? 128.718 155.663 175.739 1.00 166.73 ? 172 ASN R CG  1 
ATOM   7952 O OD1 . ASN E 5 710 ? 128.707 154.897 176.702 1.00 167.02 ? 172 ASN R OD1 1 
ATOM   7953 N ND2 . ASN E 5 710 ? 128.134 156.856 175.766 1.00 166.67 ? 172 ASN R ND2 1 
ATOM   7954 N N   . PHE E 5 711 ? 132.170 154.009 173.223 1.00 167.55 ? 173 PHE R N   1 
ATOM   7955 C CA  . PHE E 5 711 ? 132.995 153.691 172.063 1.00 166.57 ? 173 PHE R CA  1 
ATOM   7956 C C   . PHE E 5 711 ? 133.151 152.185 171.895 1.00 166.47 ? 173 PHE R C   1 
ATOM   7957 O O   . PHE E 5 711 ? 133.073 151.666 170.776 1.00 168.18 ? 173 PHE R O   1 
ATOM   7958 C CB  . PHE E 5 711 ? 134.361 154.361 172.189 1.00 165.06 ? 173 PHE R CB  1 
ATOM   7959 C CG  . PHE E 5 711 ? 134.292 155.852 172.360 1.00 167.35 ? 173 PHE R CG  1 
ATOM   7960 C CD1 . PHE E 5 711 ? 134.015 156.675 171.281 1.00 166.98 ? 173 PHE R CD1 1 
ATOM   7961 C CD2 . PHE E 5 711 ? 134.506 156.431 173.600 1.00 167.74 ? 173 PHE R CD2 1 
ATOM   7962 C CE1 . PHE E 5 711 ? 133.951 158.047 171.435 1.00 168.16 ? 173 PHE R CE1 1 
ATOM   7963 C CE2 . PHE E 5 711 ? 134.443 157.802 173.761 1.00 167.11 ? 173 PHE R CE2 1 
ATOM   7964 C CZ  . PHE E 5 711 ? 134.166 158.611 172.677 1.00 168.03 ? 173 PHE R CZ  1 
ATOM   7965 N N   . HIS E 5 712 ? 133.372 151.467 172.999 1.00 150.38 ? 174 HIS R N   1 
ATOM   7966 C CA  . HIS E 5 712 ? 133.508 150.016 172.919 1.00 151.88 ? 174 HIS R CA  1 
ATOM   7967 C C   . HIS E 5 712 ? 132.214 149.365 172.445 1.00 154.23 ? 174 HIS R C   1 
ATOM   7968 O O   . HIS E 5 712 ? 132.237 148.459 171.603 1.00 154.22 ? 174 HIS R O   1 
ATOM   7969 C CB  . HIS E 5 712 ? 133.928 149.454 174.277 1.00 150.30 ? 174 HIS R CB  1 
ATOM   7970 C CG  . HIS E 5 712 ? 134.160 147.975 174.272 1.00 152.93 ? 174 HIS R CG  1 
ATOM   7971 N ND1 . HIS E 5 712 ? 133.171 147.065 174.577 1.00 152.83 ? 174 HIS R ND1 1 
ATOM   7972 C CD2 . HIS E 5 712 ? 135.269 147.247 173.999 1.00 153.22 ? 174 HIS R CD2 1 
ATOM   7973 C CE1 . HIS E 5 712 ? 133.660 145.841 174.492 1.00 151.22 ? 174 HIS R CE1 1 
ATOM   7974 N NE2 . HIS E 5 712 ? 134.931 145.924 174.143 1.00 151.05 ? 174 HIS R NE2 1 
ATOM   7975 N N   . GLN E 5 713 ? 131.073 149.818 172.970 1.00 158.72 ? 175 GLN R N   1 
ATOM   7976 C CA  . GLN E 5 713 ? 129.798 149.246 172.550 1.00 158.96 ? 175 GLN R CA  1 
ATOM   7977 C C   . GLN E 5 713 ? 129.501 149.580 171.093 1.00 158.14 ? 175 GLN R C   1 
ATOM   7978 O O   . GLN E 5 713 ? 128.948 148.750 170.363 1.00 158.51 ? 175 GLN R O   1 
ATOM   7979 C CB  . GLN E 5 713 ? 128.673 149.721 173.477 1.00 158.53 ? 175 GLN R CB  1 
ATOM   7980 C CG  . GLN E 5 713 ? 127.927 150.974 173.037 1.00 158.78 ? 175 GLN R CG  1 
ATOM   7981 C CD  . GLN E 5 713 ? 126.724 150.662 172.166 1.00 159.92 ? 175 GLN R CD  1 
ATOM   7982 O OE1 . GLN E 5 713 ? 125.963 149.736 172.446 1.00 159.74 ? 175 GLN R OE1 1 
ATOM   7983 N NE2 . GLN E 5 713 ? 126.550 151.435 171.099 1.00 159.25 ? 175 GLN R NE2 1 
ATOM   7984 N N   . TYR E 5 714 ? 129.872 150.783 170.646 1.00 149.09 ? 176 TYR R N   1 
ATOM   7985 C CA  . TYR E 5 714 ? 129.693 151.135 169.243 1.00 147.61 ? 176 TYR R CA  1 
ATOM   7986 C C   . TYR E 5 714 ? 130.558 150.261 168.347 1.00 148.35 ? 176 TYR R C   1 
ATOM   7987 O O   . TYR E 5 714 ? 130.107 149.807 167.289 1.00 151.31 ? 176 TYR R O   1 
ATOM   7988 C CB  . TYR E 5 714 ? 130.015 152.612 169.022 1.00 148.02 ? 176 TYR R CB  1 
ATOM   7989 C CG  . TYR E 5 714 ? 130.054 153.009 167.565 1.00 149.82 ? 176 TYR R CG  1 
ATOM   7990 C CD1 . TYR E 5 714 ? 128.883 153.230 166.854 1.00 150.80 ? 176 TYR R CD1 1 
ATOM   7991 C CD2 . TYR E 5 714 ? 131.263 153.161 166.900 1.00 150.62 ? 176 TYR R CD2 1 
ATOM   7992 C CE1 . TYR E 5 714 ? 128.915 153.592 165.520 1.00 152.28 ? 176 TYR R CE1 1 
ATOM   7993 C CE2 . TYR E 5 714 ? 131.305 153.522 165.568 1.00 151.25 ? 176 TYR R CE2 1 
ATOM   7994 C CZ  . TYR E 5 714 ? 130.129 153.737 164.882 1.00 152.29 ? 176 TYR R CZ  1 
ATOM   7995 O OH  . TYR E 5 714 ? 130.167 154.098 163.555 1.00 150.76 ? 176 TYR R OH  1 
ATOM   7996 N N   . GLN E 5 715 ? 131.807 150.020 168.752 1.00 134.94 ? 177 GLN R N   1 
ATOM   7997 C CA  . GLN E 5 715 ? 132.677 149.141 167.980 1.00 136.77 ? 177 GLN R CA  1 
ATOM   7998 C C   . GLN E 5 715 ? 132.103 147.733 167.907 1.00 138.39 ? 177 GLN R C   1 
ATOM   7999 O O   . GLN E 5 715 ? 132.091 147.112 166.835 1.00 137.70 ? 177 GLN R O   1 
ATOM   8000 C CB  . GLN E 5 715 ? 134.078 149.127 168.593 1.00 133.78 ? 177 GLN R CB  1 
ATOM   8001 C CG  . GLN E 5 715 ? 134.800 147.793 168.491 1.00 137.82 ? 177 GLN R CG  1 
ATOM   8002 C CD  . GLN E 5 715 ? 134.695 146.973 169.763 1.00 138.59 ? 177 GLN R CD  1 
ATOM   8003 O OE1 . GLN E 5 715 ? 134.775 147.508 170.868 1.00 136.39 ? 177 GLN R OE1 1 
ATOM   8004 N NE2 . GLN E 5 715 ? 134.512 145.667 169.611 1.00 139.93 ? 177 GLN R NE2 1 
ATOM   8005 N N   . PHE E 5 716 ? 131.612 147.216 169.036 1.00 129.21 ? 178 PHE R N   1 
ATOM   8006 C CA  . PHE E 5 716 ? 131.032 145.878 169.046 1.00 126.96 ? 178 PHE R CA  1 
ATOM   8007 C C   . PHE E 5 716 ? 129.815 145.800 168.135 1.00 126.19 ? 178 PHE R C   1 
ATOM   8008 O O   . PHE E 5 716 ? 129.671 144.855 167.352 1.00 128.43 ? 178 PHE R O   1 
ATOM   8009 C CB  . PHE E 5 716 ? 130.660 145.475 170.473 1.00 127.37 ? 178 PHE R CB  1 
ATOM   8010 C CG  . PHE E 5 716 ? 129.778 144.262 170.548 1.00 127.62 ? 178 PHE R CG  1 
ATOM   8011 C CD1 . PHE E 5 716 ? 130.322 142.992 170.491 1.00 128.71 ? 178 PHE R CD1 1 
ATOM   8012 C CD2 . PHE E 5 716 ? 128.405 144.390 170.680 1.00 127.27 ? 178 PHE R CD2 1 
ATOM   8013 C CE1 . PHE E 5 716 ? 129.516 141.875 170.558 1.00 127.43 ? 178 PHE R CE1 1 
ATOM   8014 C CE2 . PHE E 5 716 ? 127.595 143.275 170.748 1.00 128.07 ? 178 PHE R CE2 1 
ATOM   8015 C CZ  . PHE E 5 716 ? 128.152 142.017 170.687 1.00 126.54 ? 178 PHE R CZ  1 
ATOM   8016 N N   . GLN E 5 717 ? 128.923 146.789 168.229 1.00 126.90 ? 179 GLN R N   1 
ATOM   8017 C CA  . GLN E 5 717 ? 127.730 146.792 167.390 1.00 125.56 ? 179 GLN R CA  1 
ATOM   8018 C C   . GLN E 5 717 ? 128.093 146.872 165.915 1.00 123.24 ? 179 GLN R C   1 
ATOM   8019 O O   . GLN E 5 717 ? 127.529 146.145 165.090 1.00 125.89 ? 179 GLN R O   1 
ATOM   8020 C CB  . GLN E 5 717 ? 126.817 147.953 167.778 1.00 127.36 ? 179 GLN R CB  1 
ATOM   8021 C CG  . GLN E 5 717 ? 125.754 147.598 168.803 1.00 127.93 ? 179 GLN R CG  1 
ATOM   8022 C CD  . GLN E 5 717 ? 125.271 146.168 168.669 1.00 128.70 ? 179 GLN R CD  1 
ATOM   8023 O OE1 . GLN E 5 717 ? 125.608 145.309 169.483 1.00 127.87 ? 179 GLN R OE1 1 
ATOM   8024 N NE2 . GLN E 5 717 ? 124.475 145.906 167.639 1.00 126.71 ? 179 GLN R NE2 1 
ATOM   8025 N N   . ALA E 5 718 ? 129.037 147.748 165.564 1.00 114.59 ? 180 ALA R N   1 
ATOM   8026 C CA  . ALA E 5 718 ? 129.437 147.884 164.170 1.00 117.10 ? 180 ALA R CA  1 
ATOM   8027 C C   . ALA E 5 718 ? 130.014 146.580 163.640 1.00 119.52 ? 180 ALA R C   1 
ATOM   8028 O O   . ALA E 5 718 ? 129.629 146.110 162.564 1.00 123.62 ? 180 ALA R O   1 
ATOM   8029 C CB  . ALA E 5 718 ? 130.446 149.022 164.021 1.00 115.40 ? 180 ALA R CB  1 
ATOM   8030 N N   . HIS E 5 719 ? 130.921 145.964 164.402 1.00 103.86 ? 181 HIS R N   1 
ATOM   8031 C CA  . HIS E 5 719 ? 131.537 144.720 163.956 1.00 102.57 ? 181 HIS R CA  1 
ATOM   8032 C C   . HIS E 5 719 ? 130.504 143.606 163.811 1.00 103.28 ? 181 HIS R C   1 
ATOM   8033 O O   . HIS E 5 719 ? 130.498 142.878 162.808 1.00 103.07 ? 181 HIS R O   1 
ATOM   8034 C CB  . HIS E 5 719 ? 132.632 144.308 164.935 1.00 101.18 ? 181 HIS R CB  1 
ATOM   8035 C CG  . HIS E 5 719 ? 133.929 145.026 164.741 1.00 103.08 ? 181 HIS R CG  1 
ATOM   8036 N ND1 . HIS E 5 719 ? 134.992 144.884 165.606 1.00 99.88  ? 181 HIS R ND1 1 
ATOM   8037 C CD2 . HIS E 5 719 ? 134.337 145.888 163.781 1.00 107.55 ? 181 HIS R CD2 1 
ATOM   8038 C CE1 . HIS E 5 719 ? 135.999 145.629 165.189 1.00 104.67 ? 181 HIS R CE1 1 
ATOM   8039 N NE2 . HIS E 5 719 ? 135.628 146.249 164.083 1.00 111.80 ? 181 HIS R NE2 1 
ATOM   8040 N N   . THR E 5 720 ? 129.608 143.463 164.793 1.00 105.42 ? 182 THR R N   1 
ATOM   8041 C CA  . THR E 5 720 ? 128.663 142.352 164.754 1.00 102.85 ? 182 THR R CA  1 
ATOM   8042 C C   . THR E 5 720 ? 127.618 142.546 163.662 1.00 104.00 ? 182 THR R C   1 
ATOM   8043 O O   . THR E 5 720 ? 127.214 141.575 163.014 1.00 106.35 ? 182 THR R O   1 
ATOM   8044 C CB  . THR E 5 720 ? 128.004 142.151 166.123 1.00 109.11 ? 182 THR R CB  1 
ATOM   8045 O OG1 . THR E 5 720 ? 127.285 140.911 166.129 1.00 111.37 ? 182 THR R OG1 1 
ATOM   8046 C CG2 . THR E 5 720 ? 127.044 143.283 166.464 1.00 110.35 ? 182 THR R CG2 1 
ATOM   8047 N N   . VAL E 5 721 ? 127.181 143.784 163.419 1.00 98.38  ? 183 VAL R N   1 
ATOM   8048 C CA  . VAL E 5 721 ? 126.246 144.023 162.326 1.00 98.49  ? 183 VAL R CA  1 
ATOM   8049 C C   . VAL E 5 721 ? 126.935 143.799 160.987 1.00 99.43  ? 183 VAL R C   1 
ATOM   8050 O O   . VAL E 5 721 ? 126.353 143.219 160.060 1.00 102.31 ? 183 VAL R O   1 
ATOM   8051 C CB  . VAL E 5 721 ? 125.647 145.436 162.436 1.00 99.24  ? 183 VAL R CB  1 
ATOM   8052 C CG1 . VAL E 5 721 ? 125.005 145.852 161.123 1.00 100.25 ? 183 VAL R CG1 1 
ATOM   8053 C CG2 . VAL E 5 721 ? 124.631 145.486 163.565 1.00 99.55  ? 183 VAL R CG2 1 
ATOM   8054 N N   . ALA E 5 722 ? 128.195 144.230 160.874 1.00 94.26  ? 184 ALA R N   1 
ATOM   8055 C CA  . ALA E 5 722 ? 128.968 143.985 159.664 1.00 96.14  ? 184 ALA R CA  1 
ATOM   8056 C C   . ALA E 5 722 ? 129.056 142.498 159.360 1.00 100.01 ? 184 ALA R C   1 
ATOM   8057 O O   . ALA E 5 722 ? 128.928 142.082 158.203 1.00 98.18  ? 184 ALA R O   1 
ATOM   8058 C CB  . ALA E 5 722 ? 130.366 144.579 159.822 1.00 95.50  ? 184 ALA R CB  1 
ATOM   8059 N N   . LEU E 5 723 ? 129.287 141.681 160.387 1.00 100.00 ? 185 LEU R N   1 
ATOM   8060 C CA  . LEU E 5 723 ? 129.348 140.238 160.175 1.00 90.91  ? 185 LEU R CA  1 
ATOM   8061 C C   . LEU E 5 723 ? 127.977 139.651 159.859 1.00 86.99  ? 185 LEU R C   1 
ATOM   8062 O O   . LEU E 5 723 ? 127.853 138.799 158.972 1.00 91.70  ? 185 LEU R O   1 
ATOM   8063 C CB  . LEU E 5 723 ? 129.940 139.555 161.404 1.00 93.44  ? 185 LEU R CB  1 
ATOM   8064 C CG  . LEU E 5 723 ? 131.451 139.359 161.425 1.00 96.10  ? 185 LEU R CG  1 
ATOM   8065 C CD1 . LEU E 5 723 ? 131.770 138.179 162.307 1.00 96.47  ? 185 LEU R CD1 1 
ATOM   8066 C CD2 . LEU E 5 723 ? 131.969 139.119 160.023 1.00 96.48  ? 185 LEU R CD2 1 
ATOM   8067 N N   . VAL E 5 724 ? 126.936 140.094 160.566 1.00 82.93  ? 186 VAL R N   1 
ATOM   8068 C CA  . VAL E 5 724 ? 125.658 139.397 160.515 1.00 86.35  ? 186 VAL R CA  1 
ATOM   8069 C C   . VAL E 5 724 ? 124.804 139.798 159.319 1.00 86.49  ? 186 VAL R C   1 
ATOM   8070 O O   . VAL E 5 724 ? 123.893 139.047 158.949 1.00 88.21  ? 186 VAL R O   1 
ATOM   8071 C CB  . VAL E 5 724 ? 124.876 139.622 161.820 1.00 86.97  ? 186 VAL R CB  1 
ATOM   8072 C CG1 . VAL E 5 724 ? 124.132 140.946 161.783 1.00 85.85  ? 186 VAL R CG1 1 
ATOM   8073 C CG2 . VAL E 5 724 ? 123.919 138.470 162.078 1.00 89.15  ? 186 VAL R CG2 1 
ATOM   8074 N N   . ILE E 5 725 ? 125.056 140.955 158.702 1.00 89.33  ? 187 ILE R N   1 
ATOM   8075 C CA  . ILE E 5 725 ? 124.249 141.358 157.547 1.00 90.03  ? 187 ILE R CA  1 
ATOM   8076 C C   . ILE E 5 725 ? 124.394 140.387 156.381 1.00 93.82  ? 187 ILE R C   1 
ATOM   8077 O O   . ILE E 5 725 ? 123.363 139.943 155.846 1.00 101.77 ? 187 ILE R O   1 
ATOM   8078 C CB  . ILE E 5 725 ? 124.565 142.815 157.162 1.00 93.36  ? 187 ILE R CB  1 
ATOM   8079 C CG1 . ILE E 5 725 ? 124.114 143.763 158.274 1.00 93.44  ? 187 ILE R CG1 1 
ATOM   8080 C CG2 . ILE E 5 725 ? 123.880 143.180 155.859 1.00 91.67  ? 187 ILE R CG2 1 
ATOM   8081 C CD1 . ILE E 5 725 ? 124.617 145.180 158.104 1.00 93.91  ? 187 ILE R CD1 1 
ATOM   8082 N N   . PRO E 5 726 ? 125.600 140.011 155.935 1.00 84.98  ? 188 PRO R N   1 
ATOM   8083 C CA  . PRO E 5 726 ? 125.684 138.978 154.890 1.00 81.46  ? 188 PRO R CA  1 
ATOM   8084 C C   . PRO E 5 726 ? 125.197 137.619 155.350 1.00 81.09  ? 188 PRO R C   1 
ATOM   8085 O O   . PRO E 5 726 ? 124.717 136.828 154.527 1.00 87.80  ? 188 PRO R O   1 
ATOM   8086 C CB  . PRO E 5 726 ? 127.178 138.946 154.541 1.00 81.34  ? 188 PRO R CB  1 
ATOM   8087 C CG  . PRO E 5 726 ? 127.730 140.214 155.063 1.00 85.23  ? 188 PRO R CG  1 
ATOM   8088 C CD  . PRO E 5 726 ? 126.935 140.525 156.280 1.00 85.72  ? 188 PRO R CD  1 
ATOM   8089 N N   . PHE E 5 727 ? 125.319 137.319 156.645 1.00 83.86  ? 189 PHE R N   1 
ATOM   8090 C CA  . PHE E 5 727 ? 124.960 135.992 157.127 1.00 84.48  ? 189 PHE R CA  1 
ATOM   8091 C C   . PHE E 5 727 ? 123.462 135.749 157.051 1.00 85.02  ? 189 PHE R C   1 
ATOM   8092 O O   . PHE E 5 727 ? 123.038 134.614 156.823 1.00 85.17  ? 189 PHE R O   1 
ATOM   8093 C CB  . PHE E 5 727 ? 125.452 135.789 158.557 1.00 86.00  ? 189 PHE R CB  1 
ATOM   8094 C CG  . PHE E 5 727 ? 125.376 134.364 159.021 1.00 88.27  ? 189 PHE R CG  1 
ATOM   8095 C CD1 . PHE E 5 727 ? 126.393 133.474 158.731 1.00 87.13  ? 189 PHE R CD1 1 
ATOM   8096 C CD2 . PHE E 5 727 ? 124.284 133.914 159.740 1.00 92.10  ? 189 PHE R CD2 1 
ATOM   8097 C CE1 . PHE E 5 727 ? 126.325 132.163 159.152 1.00 87.85  ? 189 PHE R CE1 1 
ATOM   8098 C CE2 . PHE E 5 727 ? 124.211 132.605 160.164 1.00 91.47  ? 189 PHE R CE2 1 
ATOM   8099 C CZ  . PHE E 5 727 ? 125.233 131.728 159.870 1.00 88.68  ? 189 PHE R CZ  1 
ATOM   8100 N N   . ILE E 5 728 ? 122.646 136.785 157.246 1.00 83.80  ? 190 ILE R N   1 
ATOM   8101 C CA  . ILE E 5 728 ? 121.202 136.612 157.116 1.00 84.70  ? 190 ILE R CA  1 
ATOM   8102 C C   . ILE E 5 728 ? 120.847 136.216 155.689 1.00 86.11  ? 190 ILE R C   1 
ATOM   8103 O O   . ILE E 5 728 ? 120.062 135.288 155.458 1.00 89.18  ? 190 ILE R O   1 
ATOM   8104 C CB  . ILE E 5 728 ? 120.464 137.890 157.549 1.00 87.11  ? 190 ILE R CB  1 
ATOM   8105 C CG1 . ILE E 5 728 ? 120.659 138.133 159.045 1.00 88.87  ? 190 ILE R CG1 1 
ATOM   8106 C CG2 . ILE E 5 728 ? 118.986 137.787 157.221 1.00 87.51  ? 190 ILE R CG2 1 
ATOM   8107 C CD1 . ILE E 5 728 ? 120.221 136.974 159.910 1.00 88.19  ? 190 ILE R CD1 1 
ATOM   8108 N N   . LEU E 5 729 ? 121.437 136.906 154.709 1.00 81.26  ? 191 LEU R N   1 
ATOM   8109 C CA  . LEU E 5 729 ? 121.198 136.562 153.312 1.00 78.91  ? 191 LEU R CA  1 
ATOM   8110 C C   . LEU E 5 729 ? 121.683 135.153 153.001 1.00 77.19  ? 191 LEU R C   1 
ATOM   8111 O O   . LEU E 5 729 ? 120.986 134.382 152.330 1.00 78.45  ? 191 LEU R O   1 
ATOM   8112 C CB  . LEU E 5 729 ? 121.888 137.575 152.401 1.00 79.21  ? 191 LEU R CB  1 
ATOM   8113 C CG  . LEU E 5 729 ? 120.997 138.371 151.450 1.00 82.35  ? 191 LEU R CG  1 
ATOM   8114 C CD1 . LEU E 5 729 ? 121.846 139.217 150.517 1.00 83.30  ? 191 LEU R CD1 1 
ATOM   8115 C CD2 . LEU E 5 729 ? 120.093 137.440 150.660 1.00 79.40  ? 191 LEU R CD2 1 
ATOM   8116 N N   . PHE E 5 730 ? 122.876 134.800 153.485 1.00 74.99  ? 192 PHE R N   1 
ATOM   8117 C CA  . PHE E 5 730 ? 123.422 133.472 153.222 1.00 66.73  ? 192 PHE R CA  1 
ATOM   8118 C C   . PHE E 5 730 ? 122.534 132.387 153.814 1.00 75.59  ? 192 PHE R C   1 
ATOM   8119 O O   . PHE E 5 730 ? 122.235 131.383 153.155 1.00 84.86  ? 192 PHE R O   1 
ATOM   8120 C CB  . PHE E 5 730 ? 124.840 133.375 153.783 1.00 63.36  ? 192 PHE R CB  1 
ATOM   8121 C CG  . PHE E 5 730 ? 125.297 131.971 154.049 1.00 64.28  ? 192 PHE R CG  1 
ATOM   8122 C CD1 . PHE E 5 730 ? 125.840 131.205 153.039 1.00 70.78  ? 192 PHE R CD1 1 
ATOM   8123 C CD2 . PHE E 5 730 ? 125.199 131.424 155.314 1.00 73.41  ? 192 PHE R CD2 1 
ATOM   8124 C CE1 . PHE E 5 730 ? 126.265 129.918 153.280 1.00 71.54  ? 192 PHE R CE1 1 
ATOM   8125 C CE2 . PHE E 5 730 ? 125.622 130.137 155.559 1.00 79.85  ? 192 PHE R CE2 1 
ATOM   8126 C CZ  . PHE E 5 730 ? 126.157 129.385 154.541 1.00 73.92  ? 192 PHE R CZ  1 
ATOM   8127 N N   . LEU E 5 731 ? 122.099 132.574 155.062 1.00 79.21  ? 193 LEU R N   1 
ATOM   8128 C CA  . LEU E 5 731 ? 121.255 131.582 155.715 1.00 81.26  ? 193 LEU R CA  1 
ATOM   8129 C C   . LEU E 5 731 ? 119.908 131.464 155.020 1.00 81.76  ? 193 LEU R C   1 
ATOM   8130 O O   . LEU E 5 731 ? 119.406 130.354 154.822 1.00 83.02  ? 193 LEU R O   1 
ATOM   8131 C CB  . LEU E 5 731 ? 121.082 131.937 157.194 1.00 80.15  ? 193 LEU R CB  1 
ATOM   8132 C CG  . LEU E 5 731 ? 120.205 131.049 158.081 1.00 82.36  ? 193 LEU R CG  1 
ATOM   8133 C CD1 . LEU E 5 731 ? 120.748 131.046 159.498 1.00 81.90  ? 193 LEU R CD1 1 
ATOM   8134 C CD2 . LEU E 5 731 ? 118.758 131.523 158.090 1.00 81.29  ? 193 LEU R CD2 1 
ATOM   8135 N N   . ALA E 5 732 ? 119.305 132.593 154.642 1.00 76.56  ? 194 ALA R N   1 
ATOM   8136 C CA  . ALA E 5 732 ? 118.022 132.536 153.953 1.00 74.42  ? 194 ALA R CA  1 
ATOM   8137 C C   . ALA E 5 732 ? 118.146 131.815 152.618 1.00 81.39  ? 194 ALA R C   1 
ATOM   8138 O O   . ALA E 5 732 ? 117.309 130.966 152.279 1.00 88.13  ? 194 ALA R O   1 
ATOM   8139 C CB  . ALA E 5 732 ? 117.470 133.946 153.753 1.00 78.64  ? 194 ALA R CB  1 
ATOM   8140 N N   . SER E 5 733 ? 119.194 132.126 151.852 1.00 77.03  ? 195 SER R N   1 
ATOM   8141 C CA  . SER E 5 733 ? 119.377 131.484 150.556 1.00 68.41  ? 195 SER R CA  1 
ATOM   8142 C C   . SER E 5 733 ? 119.613 129.989 150.715 1.00 69.56  ? 195 SER R C   1 
ATOM   8143 O O   . SER E 5 733 ? 119.010 129.176 150.004 1.00 80.43  ? 195 SER R O   1 
ATOM   8144 C CB  . SER E 5 733 ? 120.535 132.141 149.809 1.00 68.01  ? 195 SER R CB  1 
ATOM   8145 O OG  . SER E 5 733 ? 120.345 133.540 149.728 1.00 80.28  ? 195 SER R OG  1 
ATOM   8146 N N   . THR E 5 734 ? 120.480 129.604 151.657 1.00 62.30  ? 196 THR R N   1 
ATOM   8147 C CA  . THR E 5 734 ? 120.734 128.186 151.878 1.00 61.73  ? 196 THR R CA  1 
ATOM   8148 C C   . THR E 5 734 ? 119.468 127.466 152.316 1.00 76.06  ? 196 THR R C   1 
ATOM   8149 O O   . THR E 5 734 ? 119.167 126.376 151.821 1.00 92.24  ? 196 THR R O   1 
ATOM   8150 C CB  . THR E 5 734 ? 121.833 127.993 152.922 1.00 70.75  ? 196 THR R CB  1 
ATOM   8151 O OG1 . THR E 5 734 ? 123.016 128.688 152.515 1.00 81.50  ? 196 THR R OG1 1 
ATOM   8152 C CG2 . THR E 5 734 ? 122.157 126.520 153.081 1.00 72.86  ? 196 THR R CG2 1 
ATOM   8153 N N   . ILE E 5 735 ? 118.707 128.068 153.231 1.00 85.78  ? 197 ILE R N   1 
ATOM   8154 C CA  . ILE E 5 735 ? 117.500 127.425 153.738 1.00 86.64  ? 197 ILE R CA  1 
ATOM   8155 C C   . ILE E 5 735 ? 116.489 127.228 152.620 1.00 90.96  ? 197 ILE R C   1 
ATOM   8156 O O   . ILE E 5 735 ? 115.881 126.157 152.499 1.00 94.10  ? 197 ILE R O   1 
ATOM   8157 C CB  . ILE E 5 735 ? 116.909 128.240 154.903 1.00 84.23  ? 197 ILE R CB  1 
ATOM   8158 C CG1 . ILE E 5 735 ? 117.692 127.973 156.188 1.00 88.82  ? 197 ILE R CG1 1 
ATOM   8159 C CG2 . ILE E 5 735 ? 115.436 127.920 155.097 1.00 83.67  ? 197 ILE R CG2 1 
ATOM   8160 C CD1 . ILE E 5 735 ? 117.838 126.505 156.517 1.00 90.13  ? 197 ILE R CD1 1 
ATOM   8161 N N   . PHE E 5 736 ? 116.295 128.244 151.775 1.00 83.78  ? 198 PHE R N   1 
ATOM   8162 C CA  . PHE E 5 736 ? 115.293 128.088 150.729 1.00 81.80  ? 198 PHE R CA  1 
ATOM   8163 C C   . PHE E 5 736 ? 115.772 127.107 149.665 1.00 80.52  ? 198 PHE R C   1 
ATOM   8164 O O   . PHE E 5 736 ? 114.961 126.395 149.065 1.00 84.04  ? 198 PHE R O   1 
ATOM   8165 C CB  . PHE E 5 736 ? 114.940 129.431 150.095 1.00 76.95  ? 198 PHE R CB  1 
ATOM   8166 C CG  . PHE E 5 736 ? 114.475 129.317 148.672 1.00 78.07  ? 198 PHE R CG  1 
ATOM   8167 C CD1 . PHE E 5 736 ? 113.175 128.935 148.391 1.00 83.04  ? 198 PHE R CD1 1 
ATOM   8168 C CD2 . PHE E 5 736 ? 115.321 129.591 147.622 1.00 77.61  ? 198 PHE R CD2 1 
ATOM   8169 C CE1 . PHE E 5 736 ? 112.734 128.826 147.087 1.00 84.69  ? 198 PHE R CE1 1 
ATOM   8170 C CE2 . PHE E 5 736 ? 114.889 129.483 146.314 1.00 84.46  ? 198 PHE R CE2 1 
ATOM   8171 C CZ  . PHE E 5 736 ? 113.594 129.101 146.047 1.00 86.42  ? 198 PHE R CZ  1 
ATOM   8172 N N   . LEU E 5 737 ? 117.084 127.053 149.414 1.00 75.84  ? 199 LEU R N   1 
ATOM   8173 C CA  . LEU E 5 737 ? 117.603 126.060 148.479 1.00 75.91  ? 199 LEU R CA  1 
ATOM   8174 C C   . LEU E 5 737 ? 117.388 124.646 149.001 1.00 83.98  ? 199 LEU R C   1 
ATOM   8175 O O   . LEU E 5 737 ? 116.998 123.749 148.242 1.00 98.22  ? 199 LEU R O   1 
ATOM   8176 C CB  . LEU E 5 737 ? 119.083 126.312 148.204 1.00 68.07  ? 199 LEU R CB  1 
ATOM   8177 C CG  . LEU E 5 737 ? 119.605 125.762 146.878 1.00 69.95  ? 199 LEU R CG  1 
ATOM   8178 C CD1 . LEU E 5 737 ? 118.671 126.131 145.744 1.00 76.75  ? 199 LEU R CD1 1 
ATOM   8179 C CD2 . LEU E 5 737 ? 120.995 126.287 146.605 1.00 77.41  ? 199 LEU R CD2 1 
ATOM   8180 N N   . MET E 5 738 ? 117.635 124.426 150.296 1.00 69.25  ? 200 MET R N   1 
ATOM   8181 C CA  . MET E 5 738 ? 117.331 123.128 150.888 1.00 73.97  ? 200 MET R CA  1 
ATOM   8182 C C   . MET E 5 738 ? 115.849 122.818 150.779 1.00 79.59  ? 200 MET R C   1 
ATOM   8183 O O   . MET E 5 738 ? 115.465 121.685 150.472 1.00 82.29  ? 200 MET R O   1 
ATOM   8184 C CB  . MET E 5 738 ? 117.755 123.083 152.355 1.00 79.23  ? 200 MET R CB  1 
ATOM   8185 C CG  . MET E 5 738 ? 119.153 123.549 152.638 1.00 83.43  ? 200 MET R CG  1 
ATOM   8186 S SD  . MET E 5 738 ? 119.897 122.677 154.018 1.00 103.20 ? 200 MET R SD  1 
ATOM   8187 C CE  . MET E 5 738 ? 121.591 122.672 153.479 1.00 84.46  ? 200 MET R CE  1 
ATOM   8188 N N   . ALA E 5 739 ? 114.999 123.812 151.042 1.00 83.04  ? 201 ALA R N   1 
ATOM   8189 C CA  . ALA E 5 739 ? 113.561 123.594 150.955 1.00 87.92  ? 201 ALA R CA  1 
ATOM   8190 C C   . ALA E 5 739 ? 113.153 123.194 149.546 1.00 90.85  ? 201 ALA R C   1 
ATOM   8191 O O   . ALA E 5 739 ? 112.377 122.252 149.363 1.00 91.72  ? 201 ALA R O   1 
ATOM   8192 C CB  . ALA E 5 739 ? 112.813 124.851 151.396 1.00 85.37  ? 201 ALA R CB  1 
ATOM   8193 N N   . SER E 5 740 ? 113.683 123.885 148.537 1.00 84.73  ? 202 SER R N   1 
ATOM   8194 C CA  . SER E 5 740 ? 113.334 123.577 147.155 1.00 79.40  ? 202 SER R CA  1 
ATOM   8195 C C   . SER E 5 740 ? 113.826 122.192 146.757 1.00 82.03  ? 202 SER R C   1 
ATOM   8196 O O   . SER E 5 740 ? 113.089 121.413 146.140 1.00 91.65  ? 202 SER R O   1 
ATOM   8197 C CB  . SER E 5 740 ? 113.907 124.643 146.222 1.00 81.63  ? 202 SER R CB  1 
ATOM   8198 O OG  . SER E 5 740 ? 113.634 124.334 144.868 1.00 89.06  ? 202 SER R OG  1 
ATOM   8199 N N   . LEU E 5 741 ? 115.072 121.862 147.104 1.00 64.28  ? 203 LEU R N   1 
ATOM   8200 C CA  . LEU E 5 741 ? 115.608 120.557 146.732 1.00 65.33  ? 203 LEU R CA  1 
ATOM   8201 C C   . LEU E 5 741 ? 114.860 119.427 147.430 1.00 78.65  ? 203 LEU R C   1 
ATOM   8202 O O   . LEU E 5 741 ? 114.544 118.409 146.804 1.00 85.68  ? 203 LEU R O   1 
ATOM   8203 C CB  . LEU E 5 741 ? 117.102 120.491 147.036 1.00 61.77  ? 203 LEU R CB  1 
ATOM   8204 C CG  . LEU E 5 741 ? 117.996 121.282 146.081 1.00 62.61  ? 203 LEU R CG  1 
ATOM   8205 C CD1 . LEU E 5 741 ? 119.444 120.855 146.227 1.00 66.76  ? 203 LEU R CD1 1 
ATOM   8206 C CD2 . LEU E 5 741 ? 117.532 121.116 144.650 1.00 68.85  ? 203 LEU R CD2 1 
ATOM   8207 N N   . THR E 5 742 ? 114.553 119.586 148.720 1.00 88.62  ? 204 THR R N   1 
ATOM   8208 C CA  . THR E 5 742 ? 113.806 118.551 149.427 1.00 92.31  ? 204 THR R CA  1 
ATOM   8209 C C   . THR E 5 742 ? 112.373 118.449 148.924 1.00 93.70  ? 204 THR R C   1 
ATOM   8210 O O   . THR E 5 742 ? 111.816 117.347 148.870 1.00 92.65  ? 204 THR R O   1 
ATOM   8211 C CB  . THR E 5 742 ? 113.822 118.820 150.930 1.00 91.86  ? 204 THR R CB  1 
ATOM   8212 O OG1 . THR E 5 742 ? 113.415 120.171 151.181 1.00 99.87  ? 204 THR R OG1 1 
ATOM   8213 C CG2 . THR E 5 742 ? 115.217 118.599 151.494 1.00 95.17  ? 204 THR R CG2 1 
ATOM   8214 N N   . LYS E 5 743 ? 111.759 119.576 148.558 1.00 90.58  ? 205 LYS R N   1 
ATOM   8215 C CA  . LYS E 5 743 ? 110.426 119.534 147.972 1.00 88.32  ? 205 LYS R CA  1 
ATOM   8216 C C   . LYS E 5 743 ? 110.439 118.783 146.650 1.00 89.62  ? 205 LYS R C   1 
ATOM   8217 O O   . LYS E 5 743 ? 109.524 118.007 146.361 1.00 99.10  ? 205 LYS R O   1 
ATOM   8218 C CB  . LYS E 5 743 ? 109.896 120.955 147.785 1.00 90.97  ? 205 LYS R CB  1 
ATOM   8219 C CG  . LYS E 5 743 ? 108.779 121.077 146.766 1.00 93.09  ? 205 LYS R CG  1 
ATOM   8220 C CD  . LYS E 5 743 ? 108.493 122.533 146.434 1.00 97.53  ? 205 LYS R CD  1 
ATOM   8221 C CE  . LYS E 5 743 ? 109.757 123.264 146.014 1.00 98.56  ? 205 LYS R CE  1 
ATOM   8222 N NZ  . LYS E 5 743 ? 110.413 122.616 144.845 1.00 97.25  ? 205 LYS R NZ  1 
ATOM   8223 N N   . GLN E 5 744 ? 111.471 119.000 145.834 1.00 82.41  ? 206 GLN R N   1 
ATOM   8224 C CA  . GLN E 5 744 ? 111.586 118.250 144.587 1.00 86.13  ? 206 GLN R CA  1 
ATOM   8225 C C   . GLN E 5 744 ? 111.829 116.770 144.852 1.00 88.28  ? 206 GLN R C   1 
ATOM   8226 O O   . GLN E 5 744 ? 111.321 115.912 144.121 1.00 89.84  ? 206 GLN R O   1 
ATOM   8227 C CB  . GLN E 5 744 ? 112.699 118.835 143.722 1.00 82.70  ? 206 GLN R CB  1 
ATOM   8228 C CG  . GLN E 5 744 ? 112.384 120.217 143.191 1.00 86.92  ? 206 GLN R CG  1 
ATOM   8229 C CD  . GLN E 5 744 ? 113.585 120.885 142.570 1.00 89.92  ? 206 GLN R CD  1 
ATOM   8230 O OE1 . GLN E 5 744 ? 114.630 120.262 142.390 1.00 93.34  ? 206 GLN R OE1 1 
ATOM   8231 N NE2 . GLN E 5 744 ? 113.448 122.162 142.243 1.00 86.14  ? 206 GLN R NE2 1 
ATOM   8232 N N   . ILE E 5 745 ? 112.610 116.452 145.886 1.00 88.82  ? 207 ILE R N   1 
ATOM   8233 C CA  . ILE E 5 745 ? 112.866 115.054 146.224 1.00 90.85  ? 207 ILE R CA  1 
ATOM   8234 C C   . ILE E 5 745 ? 111.572 114.361 146.635 1.00 94.60  ? 207 ILE R C   1 
ATOM   8235 O O   . ILE E 5 745 ? 111.262 113.256 146.174 1.00 99.41  ? 207 ILE R O   1 
ATOM   8236 C CB  . ILE E 5 745 ? 113.928 114.956 147.333 1.00 90.30  ? 207 ILE R CB  1 
ATOM   8237 C CG1 . ILE E 5 745 ? 115.314 115.302 146.787 1.00 93.56  ? 207 ILE R CG1 1 
ATOM   8238 C CG2 . ILE E 5 745 ? 113.927 113.568 147.950 1.00 90.65  ? 207 ILE R CG2 1 
ATOM   8239 C CD1 . ILE E 5 745 ? 115.971 114.181 146.027 1.00 95.62  ? 207 ILE R CD1 1 
ATOM   8240 N N   . GLN E 5 746 ? 110.793 115.006 147.503 1.00 107.19 ? 208 GLN R N   1 
ATOM   8241 C CA  . GLN E 5 746 ? 109.584 114.384 148.031 1.00 108.65 ? 208 GLN R CA  1 
ATOM   8242 C C   . GLN E 5 746 ? 108.441 114.382 147.024 1.00 110.97 ? 208 GLN R C   1 
ATOM   8243 O O   . GLN E 5 746 ? 107.608 113.470 147.045 1.00 111.54 ? 208 GLN R O   1 
ATOM   8244 C CB  . GLN E 5 746 ? 109.146 115.095 149.312 1.00 108.66 ? 208 GLN R CB  1 
ATOM   8245 C CG  . GLN E 5 746 ? 109.845 114.601 150.566 1.00 110.73 ? 208 GLN R CG  1 
ATOM   8246 C CD  . GLN E 5 746 ? 109.877 115.645 151.664 1.00 113.11 ? 208 GLN R CD  1 
ATOM   8247 O OE1 . GLN E 5 746 ? 109.902 116.846 151.394 1.00 112.67 ? 208 GLN R OE1 1 
ATOM   8248 N NE2 . GLN E 5 746 ? 109.875 115.192 152.912 1.00 111.94 ? 208 GLN R NE2 1 
ATOM   8249 N N   . HIS E 5 747 ? 108.381 115.384 146.146 1.00 116.42 ? 209 HIS R N   1 
ATOM   8250 C CA  . HIS E 5 747 ? 107.263 115.496 145.216 1.00 115.54 ? 209 HIS R CA  1 
ATOM   8251 C C   . HIS E 5 747 ? 107.285 114.392 144.170 1.00 115.07 ? 209 HIS R C   1 
ATOM   8252 O O   . HIS E 5 747 ? 106.236 114.053 143.610 1.00 114.29 ? 209 HIS R O   1 
ATOM   8253 C CB  . HIS E 5 747 ? 107.279 116.884 144.565 1.00 116.31 ? 209 HIS R CB  1 
ATOM   8254 C CG  . HIS E 5 747 ? 106.704 116.926 143.182 1.00 119.40 ? 209 HIS R CG  1 
ATOM   8255 N ND1 . HIS E 5 747 ? 107.361 116.417 142.082 1.00 120.91 ? 209 HIS R ND1 1 
ATOM   8256 C CD2 . HIS E 5 747 ? 105.531 117.422 142.722 1.00 119.49 ? 209 HIS R CD2 1 
ATOM   8257 C CE1 . HIS E 5 747 ? 106.617 116.596 141.005 1.00 118.57 ? 209 HIS R CE1 1 
ATOM   8258 N NE2 . HIS E 5 747 ? 105.501 117.203 141.366 1.00 120.15 ? 209 HIS R NE2 1 
ATOM   8259 N N   . HIS E 5 748 ? 108.455 113.822 143.893 1.00 119.41 ? 210 HIS R N   1 
ATOM   8260 C CA  . HIS E 5 748 ? 108.555 112.777 142.884 1.00 121.38 ? 210 HIS R CA  1 
ATOM   8261 C C   . HIS E 5 748 ? 107.708 111.573 143.279 1.00 125.68 ? 210 HIS R C   1 
ATOM   8262 O O   . HIS E 5 748 ? 107.727 111.130 144.432 1.00 126.30 ? 210 HIS R O   1 
ATOM   8263 C CB  . HIS E 5 748 ? 110.019 112.375 142.682 1.00 121.29 ? 210 HIS R CB  1 
ATOM   8264 C CG  . HIS E 5 748 ? 110.473 111.256 143.567 1.00 124.23 ? 210 HIS R CG  1 
ATOM   8265 N ND1 . HIS E 5 748 ? 110.345 111.292 144.939 1.00 125.12 ? 210 HIS R ND1 1 
ATOM   8266 C CD2 . HIS E 5 748 ? 111.057 110.069 143.276 1.00 123.01 ? 210 HIS R CD2 1 
ATOM   8267 C CE1 . HIS E 5 748 ? 110.828 110.176 145.454 1.00 122.80 ? 210 HIS R CE1 1 
ATOM   8268 N NE2 . HIS E 5 748 ? 111.267 109.417 144.466 1.00 121.59 ? 210 HIS R NE2 1 
ATOM   8269 N N   . SER E 5 749 ? 106.939 111.065 142.319 1.00 150.27 ? 211 SER R N   1 
ATOM   8270 C CA  . SER E 5 749 ? 106.069 109.914 142.548 1.00 150.75 ? 211 SER R CA  1 
ATOM   8271 C C   . SER E 5 749 ? 105.743 109.304 141.196 1.00 151.26 ? 211 SER R C   1 
ATOM   8272 O O   . SER E 5 749 ? 105.147 109.976 140.347 1.00 149.67 ? 211 SER R O   1 
ATOM   8273 C CB  . SER E 5 749 ? 104.793 110.326 143.282 1.00 150.02 ? 211 SER R CB  1 
ATOM   8274 O OG  . SER E 5 749 ? 103.928 109.218 143.464 1.00 149.73 ? 211 SER R OG  1 
ATOM   8275 N N   . THR E 5 750 ? 106.157 108.052 140.990 1.00 158.58 ? 212 THR R N   1 
ATOM   8276 C CA  . THR E 5 750 ? 106.024 107.278 139.757 1.00 158.56 ? 212 THR R CA  1 
ATOM   8277 C C   . THR E 5 750 ? 106.935 107.840 138.661 1.00 157.55 ? 212 THR R C   1 
ATOM   8278 O O   . THR E 5 750 ? 107.118 107.196 137.619 1.00 157.93 ? 212 THR R O   1 
ATOM   8279 C CB  . THR E 5 750 ? 104.555 107.211 139.288 1.00 158.25 ? 212 THR R CB  1 
ATOM   8280 O OG1 . THR E 5 750 ? 103.777 106.546 140.291 1.00 158.20 ? 212 THR R OG1 1 
ATOM   8281 C CG2 . THR E 5 750 ? 104.386 106.427 137.991 1.00 155.99 ? 212 THR R CG2 1 
ATOM   8282 N N   . GLY E 5 751 ? 107.587 108.973 138.903 1.00 131.93 ? 213 GLY R N   1 
ATOM   8283 C CA  . GLY E 5 751 ? 108.540 109.533 137.968 1.00 129.43 ? 213 GLY R CA  1 
ATOM   8284 C C   . GLY E 5 751 ? 109.947 109.470 138.519 1.00 127.66 ? 213 GLY R C   1 
ATOM   8285 O O   . GLY E 5 751 ? 110.706 110.437 138.419 1.00 124.35 ? 213 GLY R O   1 
ATOM   8286 N N   . HIS E 5 752 ? 110.290 108.337 139.129 1.00 130.44 ? 214 HIS R N   1 
ATOM   8287 C CA  . HIS E 5 752 ? 111.584 108.187 139.782 1.00 132.91 ? 214 HIS R CA  1 
ATOM   8288 C C   . HIS E 5 752 ? 112.713 108.356 138.773 1.00 134.10 ? 214 HIS R C   1 
ATOM   8289 O O   . HIS E 5 752 ? 112.685 107.775 137.684 1.00 132.97 ? 214 HIS R O   1 
ATOM   8290 C CB  . HIS E 5 752 ? 111.662 106.814 140.457 1.00 131.64 ? 214 HIS R CB  1 
ATOM   8291 C CG  . HIS E 5 752 ? 112.838 106.642 141.371 1.00 134.75 ? 214 HIS R CG  1 
ATOM   8292 N ND1 . HIS E 5 752 ? 114.106 107.079 141.056 1.00 136.31 ? 214 HIS R ND1 1 
ATOM   8293 C CD2 . HIS E 5 752 ? 112.931 106.076 142.598 1.00 133.23 ? 214 HIS R CD2 1 
ATOM   8294 C CE1 . HIS E 5 752 ? 114.929 106.791 142.049 1.00 134.46 ? 214 HIS R CE1 1 
ATOM   8295 N NE2 . HIS E 5 752 ? 114.241 106.182 142.996 1.00 132.65 ? 214 HIS R NE2 1 
ATOM   8296 N N   . CYS E 5 753 ? 113.711 109.159 139.143 1.00 118.96 ? 215 CYS R N   1 
ATOM   8297 C CA  . CYS E 5 753 ? 114.898 109.403 138.323 1.00 117.78 ? 215 CYS R CA  1 
ATOM   8298 C C   . CYS E 5 753 ? 116.115 109.195 139.222 1.00 113.69 ? 215 CYS R C   1 
ATOM   8299 O O   . CYS E 5 753 ? 116.562 110.125 139.898 1.00 108.40 ? 215 CYS R O   1 
ATOM   8300 C CB  . CYS E 5 753 ? 114.871 110.801 137.717 1.00 116.23 ? 215 CYS R CB  1 
ATOM   8301 S SG  . CYS E 5 753 ? 113.287 111.282 137.006 1.00 109.70 ? 215 CYS R SG  1 
ATOM   8302 N N   . ASN E 5 754 ? 116.651 107.975 139.223 1.00 119.46 ? 216 ASN R N   1 
ATOM   8303 C CA  . ASN E 5 754 ? 117.719 107.644 140.165 1.00 118.34 ? 216 ASN R CA  1 
ATOM   8304 C C   . ASN E 5 754 ? 118.967 108.500 139.975 1.00 118.14 ? 216 ASN R C   1 
ATOM   8305 O O   . ASN E 5 754 ? 119.487 109.011 140.981 1.00 122.38 ? 216 ASN R O   1 
ATOM   8306 C CB  . ASN E 5 754 ? 118.033 106.146 140.084 1.00 121.54 ? 216 ASN R CB  1 
ATOM   8307 C CG  . ASN E 5 754 ? 118.742 105.634 141.321 1.00 122.00 ? 216 ASN R CG  1 
ATOM   8308 O OD1 . ASN E 5 754 ? 119.874 106.023 141.608 1.00 119.97 ? 216 ASN R OD1 1 
ATOM   8309 N ND2 . ASN E 5 754 ? 118.077 104.758 142.063 1.00 122.95 ? 216 ASN R ND2 1 
ATOM   8310 N N   . PRO E 5 755 ? 119.509 108.690 138.764 1.00 116.24 ? 217 PRO R N   1 
ATOM   8311 C CA  . PRO E 5 755 ? 120.619 109.651 138.628 1.00 115.48 ? 217 PRO R CA  1 
ATOM   8312 C C   . PRO E 5 755 ? 120.259 111.068 139.048 1.00 114.49 ? 217 PRO R C   1 
ATOM   8313 O O   . PRO E 5 755 ? 121.080 111.753 139.671 1.00 113.14 ? 217 PRO R O   1 
ATOM   8314 C CB  . PRO E 5 755 ? 120.966 109.570 137.136 1.00 117.64 ? 217 PRO R CB  1 
ATOM   8315 C CG  . PRO E 5 755 ? 120.569 108.200 136.742 1.00 118.10 ? 217 PRO R CG  1 
ATOM   8316 C CD  . PRO E 5 755 ? 119.331 107.894 137.534 1.00 117.46 ? 217 PRO R CD  1 
ATOM   8317 N N   . SER E 5 756 ? 119.043 111.526 138.743 1.00 116.77 ? 218 SER R N   1 
ATOM   8318 C CA  . SER E 5 756 ? 118.679 112.903 139.065 1.00 114.67 ? 218 SER R CA  1 
ATOM   8319 C C   . SER E 5 756 ? 118.457 113.087 140.560 1.00 115.34 ? 218 SER R C   1 
ATOM   8320 O O   . SER E 5 756 ? 118.885 114.094 141.135 1.00 120.03 ? 218 SER R O   1 
ATOM   8321 C CB  . SER E 5 756 ? 117.434 113.314 138.286 1.00 113.45 ? 218 SER R CB  1 
ATOM   8322 O OG  . SER E 5 756 ? 117.667 113.254 136.890 1.00 117.43 ? 218 SER R OG  1 
ATOM   8323 N N   . MET E 5 757 ? 117.781 112.136 141.207 1.00 107.37 ? 219 MET R N   1 
ATOM   8324 C CA  . MET E 5 757 ? 117.674 112.184 142.660 1.00 106.99 ? 219 MET R CA  1 
ATOM   8325 C C   . MET E 5 757 ? 119.032 112.022 143.327 1.00 103.47 ? 219 MET R C   1 
ATOM   8326 O O   . MET E 5 757 ? 119.271 112.605 144.388 1.00 104.61 ? 219 MET R O   1 
ATOM   8327 C CB  . MET E 5 757 ? 116.688 111.126 143.160 1.00 105.56 ? 219 MET R CB  1 
ATOM   8328 C CG  . MET E 5 757 ? 115.312 111.660 143.574 1.00 104.79 ? 219 MET R CG  1 
ATOM   8329 S SD  . MET E 5 757 ? 114.467 112.912 142.579 1.00 113.15 ? 219 MET R SD  1 
ATOM   8330 C CE  . MET E 5 757 ? 114.597 112.267 140.920 1.00 106.49 ? 219 MET R CE  1 
ATOM   8331 N N   . LYS E 5 758 ? 119.938 111.254 142.720 1.00 91.63  ? 220 LYS R N   1 
ATOM   8332 C CA  . LYS E 5 758 ? 121.297 111.167 143.242 1.00 91.60  ? 220 LYS R CA  1 
ATOM   8333 C C   . LYS E 5 758 ? 121.994 112.520 143.181 1.00 96.95  ? 220 LYS R C   1 
ATOM   8334 O O   . LYS E 5 758 ? 122.646 112.937 144.146 1.00 100.54 ? 220 LYS R O   1 
ATOM   8335 C CB  . LYS E 5 758 ? 122.091 110.120 142.462 1.00 91.14  ? 220 LYS R CB  1 
ATOM   8336 C CG  . LYS E 5 758 ? 123.577 110.110 142.766 1.00 93.20  ? 220 LYS R CG  1 
ATOM   8337 C CD  . LYS E 5 758 ? 123.841 109.604 144.171 1.00 95.50  ? 220 LYS R CD  1 
ATOM   8338 C CE  . LYS E 5 758 ? 125.330 109.510 144.450 1.00 98.36  ? 220 LYS R CE  1 
ATOM   8339 N NZ  . LYS E 5 758 ? 126.027 108.668 143.441 1.00 98.43  ? 220 LYS R NZ  1 
ATOM   8340 N N   . ALA E 5 759 ? 121.861 113.221 142.054 1.00 85.72  ? 221 ALA R N   1 
ATOM   8341 C CA  . ALA E 5 759 ? 122.451 114.550 141.932 1.00 81.47  ? 221 ALA R CA  1 
ATOM   8342 C C   . ALA E 5 759 ? 121.825 115.523 142.923 1.00 77.85  ? 221 ALA R C   1 
ATOM   8343 O O   . ALA E 5 759 ? 122.526 116.345 143.526 1.00 83.61  ? 221 ALA R O   1 
ATOM   8344 C CB  . ALA E 5 759 ? 122.297 115.066 140.503 1.00 78.56  ? 221 ALA R CB  1 
ATOM   8345 N N   . ARG E 5 760 ? 120.506 115.449 143.101 1.00 61.09  ? 222 ARG R N   1 
ATOM   8346 C CA  . ARG E 5 760 ? 119.835 116.332 144.048 1.00 60.91  ? 222 ARG R CA  1 
ATOM   8347 C C   . ARG E 5 760 ? 120.294 116.064 145.476 1.00 76.08  ? 222 ARG R C   1 
ATOM   8348 O O   . ARG E 5 760 ? 120.526 117.001 146.248 1.00 91.74  ? 222 ARG R O   1 
ATOM   8349 C CB  . ARG E 5 760 ? 118.321 116.173 143.931 1.00 58.97  ? 222 ARG R CB  1 
ATOM   8350 C CG  . ARG E 5 760 ? 117.541 117.385 144.393 1.00 69.09  ? 222 ARG R CG  1 
ATOM   8351 C CD  . ARG E 5 760 ? 116.181 117.463 143.719 1.00 73.53  ? 222 ARG R CD  1 
ATOM   8352 N NE  . ARG E 5 760 ? 116.287 117.530 142.267 1.00 68.32  ? 222 ARG R NE  1 
ATOM   8353 C CZ  . ARG E 5 760 ? 115.737 116.656 141.437 1.00 72.43  ? 222 ARG R CZ  1 
ATOM   8354 N NH1 . ARG E 5 760 ? 115.029 115.632 141.881 1.00 78.27  ? 222 ARG R NH1 1 
ATOM   8355 N NH2 . ARG E 5 760 ? 115.900 116.815 140.127 1.00 72.95  ? 222 ARG R NH2 1 
ATOM   8356 N N   . PHE E 5 761 ? 120.433 114.789 145.846 1.00 77.51  ? 223 PHE R N   1 
ATOM   8357 C CA  . PHE E 5 761 ? 120.913 114.447 147.180 1.00 69.06  ? 223 PHE R CA  1 
ATOM   8358 C C   . PHE E 5 761 ? 122.355 114.891 147.379 1.00 64.45  ? 223 PHE R C   1 
ATOM   8359 O O   . PHE E 5 761 ? 122.720 115.360 148.462 1.00 74.83  ? 223 PHE R O   1 
ATOM   8360 C CB  . PHE E 5 761 ? 120.776 112.945 147.417 1.00 73.91  ? 223 PHE R CB  1 
ATOM   8361 C CG  . PHE E 5 761 ? 119.412 112.528 147.880 1.00 73.85  ? 223 PHE R CG  1 
ATOM   8362 C CD1 . PHE E 5 761 ? 118.651 113.365 148.676 1.00 76.80  ? 223 PHE R CD1 1 
ATOM   8363 C CD2 . PHE E 5 761 ? 118.890 111.299 147.518 1.00 71.85  ? 223 PHE R CD2 1 
ATOM   8364 C CE1 . PHE E 5 761 ? 117.397 112.985 149.101 1.00 75.25  ? 223 PHE R CE1 1 
ATOM   8365 C CE2 . PHE E 5 761 ? 117.636 110.914 147.941 1.00 76.61  ? 223 PHE R CE2 1 
ATOM   8366 C CZ  . PHE E 5 761 ? 116.889 111.757 148.734 1.00 78.92  ? 223 PHE R CZ  1 
ATOM   8367 N N   . THR E 5 762 ? 123.192 114.744 146.351 1.00 53.95  ? 224 THR R N   1 
ATOM   8368 C CA  . THR E 5 762 ? 124.567 115.221 146.447 1.00 59.66  ? 224 THR R CA  1 
ATOM   8369 C C   . THR E 5 762 ? 124.612 116.731 146.640 1.00 65.47  ? 224 THR R C   1 
ATOM   8370 O O   . THR E 5 762 ? 125.389 117.240 147.457 1.00 72.43  ? 224 THR R O   1 
ATOM   8371 C CB  . THR E 5 762 ? 125.349 114.820 145.199 1.00 62.34  ? 224 THR R CB  1 
ATOM   8372 O OG1 . THR E 5 762 ? 125.305 113.397 145.045 1.00 67.76  ? 224 THR R OG1 1 
ATOM   8373 C CG2 . THR E 5 762 ? 126.794 115.266 145.310 1.00 62.12  ? 224 THR R CG2 1 
ATOM   8374 N N   . ALA E 5 763 ? 123.780 117.464 145.897 1.00 63.67  ? 225 ALA R N   1 
ATOM   8375 C CA  . ALA E 5 763 ? 123.726 118.912 146.058 1.00 55.67  ? 225 ALA R CA  1 
ATOM   8376 C C   . ALA E 5 763 ? 123.249 119.293 147.452 1.00 60.58  ? 225 ALA R C   1 
ATOM   8377 O O   . ALA E 5 763 ? 123.781 120.225 148.066 1.00 78.67  ? 225 ALA R O   1 
ATOM   8378 C CB  . ALA E 5 763 ? 122.818 119.524 144.994 1.00 59.93  ? 225 ALA R CB  1 
ATOM   8379 N N   . LEU E 5 764 ? 122.244 118.584 147.967 1.00 50.87  ? 226 LEU R N   1 
ATOM   8380 C CA  . LEU E 5 764 ? 121.748 118.874 149.308 1.00 62.09  ? 226 LEU R CA  1 
ATOM   8381 C C   . LEU E 5 764 ? 122.814 118.596 150.361 1.00 69.25  ? 226 LEU R C   1 
ATOM   8382 O O   . LEU E 5 764 ? 122.966 119.363 151.317 1.00 67.90  ? 226 LEU R O   1 
ATOM   8383 C CB  . LEU E 5 764 ? 120.486 118.063 149.586 1.00 59.07  ? 226 LEU R CB  1 
ATOM   8384 C CG  . LEU E 5 764 ? 119.756 118.398 150.884 1.00 66.15  ? 226 LEU R CG  1 
ATOM   8385 C CD1 . LEU E 5 764 ? 119.096 119.759 150.779 1.00 67.32  ? 226 LEU R CD1 1 
ATOM   8386 C CD2 . LEU E 5 764 ? 118.731 117.327 151.208 1.00 69.13  ? 226 LEU R CD2 1 
ATOM   8387 N N   . ARG E 5 765 ? 123.566 117.506 150.200 1.00 63.86  ? 227 ARG R N   1 
ATOM   8388 C CA  . ARG E 5 765 ? 124.643 117.204 151.137 1.00 62.16  ? 227 ARG R CA  1 
ATOM   8389 C C   . ARG E 5 765 ? 125.737 118.263 151.085 1.00 69.95  ? 227 ARG R C   1 
ATOM   8390 O O   . ARG E 5 765 ? 126.264 118.674 152.126 1.00 81.72  ? 227 ARG R O   1 
ATOM   8391 C CB  . ARG E 5 765 ? 125.226 115.823 150.841 1.00 64.01  ? 227 ARG R CB  1 
ATOM   8392 C CG  . ARG E 5 765 ? 126.454 115.489 151.667 1.00 63.74  ? 227 ARG R CG  1 
ATOM   8393 C CD  . ARG E 5 765 ? 127.647 115.184 150.783 1.00 64.97  ? 227 ARG R CD  1 
ATOM   8394 N NE  . ARG E 5 765 ? 127.424 114.009 149.951 1.00 68.52  ? 227 ARG R NE  1 
ATOM   8395 C CZ  . ARG E 5 765 ? 128.269 113.578 149.026 1.00 70.24  ? 227 ARG R CZ  1 
ATOM   8396 N NH1 . ARG E 5 765 ? 129.405 114.209 148.779 1.00 70.82  ? 227 ARG R NH1 1 
ATOM   8397 N NH2 . ARG E 5 765 ? 127.966 112.486 148.330 1.00 69.02  ? 227 ARG R NH2 1 
ATOM   8398 N N   . SER E 5 766 ? 126.104 118.705 149.880 1.00 66.23  ? 228 SER R N   1 
ATOM   8399 C CA  . SER E 5 766 ? 127.121 119.744 149.760 1.00 67.04  ? 228 SER R CA  1 
ATOM   8400 C C   . SER E 5 766 ? 126.651 121.046 150.395 1.00 69.57  ? 228 SER R C   1 
ATOM   8401 O O   . SER E 5 766 ? 127.424 121.729 151.081 1.00 78.70  ? 228 SER R O   1 
ATOM   8402 C CB  . SER E 5 766 ? 127.483 119.958 148.292 1.00 65.76  ? 228 SER R CB  1 
ATOM   8403 O OG  . SER E 5 766 ? 128.509 120.923 148.159 1.00 72.58  ? 228 SER R OG  1 
ATOM   8404 N N   . LEU E 5 767 ? 125.383 121.403 150.185 1.00 62.91  ? 229 LEU R N   1 
ATOM   8405 C CA  . LEU E 5 767 ? 124.835 122.596 150.820 1.00 57.60  ? 229 LEU R CA  1 
ATOM   8406 C C   . LEU E 5 767 ? 124.826 122.458 152.334 1.00 67.15  ? 229 LEU R C   1 
ATOM   8407 O O   . LEU E 5 767 ? 125.083 123.429 153.050 1.00 83.70  ? 229 LEU R O   1 
ATOM   8408 C CB  . LEU E 5 767 ? 123.427 122.872 150.302 1.00 55.95  ? 229 LEU R CB  1 
ATOM   8409 C CG  . LEU E 5 767 ? 123.331 123.470 148.902 1.00 65.07  ? 229 LEU R CG  1 
ATOM   8410 C CD1 . LEU E 5 767 ? 121.931 123.279 148.356 1.00 71.96  ? 229 LEU R CD1 1 
ATOM   8411 C CD2 . LEU E 5 767 ? 123.706 124.940 148.926 1.00 70.04  ? 229 LEU R CD2 1 
ATOM   8412 N N   . ALA E 5 768 ? 124.514 121.264 152.843 1.00 64.45  ? 230 ALA R N   1 
ATOM   8413 C CA  . ALA E 5 768 ? 124.537 121.050 154.287 1.00 67.04  ? 230 ALA R CA  1 
ATOM   8414 C C   . ALA E 5 768 ? 125.942 121.216 154.845 1.00 70.26  ? 230 ALA R C   1 
ATOM   8415 O O   . ALA E 5 768 ? 126.132 121.848 155.892 1.00 73.40  ? 230 ALA R O   1 
ATOM   8416 C CB  . ALA E 5 768 ? 123.984 119.667 154.623 1.00 74.04  ? 230 ALA R CB  1 
ATOM   8417 N N   . VAL E 5 769 ? 126.938 120.657 154.157 1.00 66.37  ? 231 VAL R N   1 
ATOM   8418 C CA  . VAL E 5 769 ? 128.323 120.811 154.595 1.00 66.65  ? 231 VAL R CA  1 
ATOM   8419 C C   . VAL E 5 769 ? 128.705 122.284 154.621 1.00 69.35  ? 231 VAL R C   1 
ATOM   8420 O O   . VAL E 5 769 ? 129.271 122.783 155.603 1.00 70.68  ? 231 VAL R O   1 
ATOM   8421 C CB  . VAL E 5 769 ? 129.265 120.001 153.686 1.00 66.15  ? 231 VAL R CB  1 
ATOM   8422 C CG1 . VAL E 5 769 ? 130.676 120.556 153.751 1.00 65.54  ? 231 VAL R CG1 1 
ATOM   8423 C CG2 . VAL E 5 769 ? 129.247 118.534 154.080 1.00 66.45  ? 231 VAL R CG2 1 
ATOM   8424 N N   . LEU E 5 770 ? 128.379 123.007 153.546 1.00 72.45  ? 232 LEU R N   1 
ATOM   8425 C CA  . LEU E 5 770 ? 128.723 124.423 153.474 1.00 70.13  ? 232 LEU R CA  1 
ATOM   8426 C C   . LEU E 5 770 ? 128.030 125.220 154.570 1.00 68.32  ? 232 LEU R C   1 
ATOM   8427 O O   . LEU E 5 770 ? 128.655 126.064 155.221 1.00 76.39  ? 232 LEU R O   1 
ATOM   8428 C CB  . LEU E 5 770 ? 128.357 124.982 152.102 1.00 72.27  ? 232 LEU R CB  1 
ATOM   8429 C CG  . LEU E 5 770 ? 129.271 126.087 151.582 1.00 77.40  ? 232 LEU R CG  1 
ATOM   8430 C CD1 . LEU E 5 770 ? 130.652 125.530 151.303 1.00 81.20  ? 232 LEU R CD1 1 
ATOM   8431 C CD2 . LEU E 5 770 ? 128.683 126.722 150.336 1.00 80.64  ? 232 LEU R CD2 1 
ATOM   8432 N N   . PHE E 5 771 ? 126.740 124.964 154.792 1.00 57.94  ? 233 PHE R N   1 
ATOM   8433 C CA  . PHE E 5 771 ? 125.998 125.709 155.799 1.00 59.18  ? 233 PHE R CA  1 
ATOM   8434 C C   . PHE E 5 771 ? 126.545 125.446 157.192 1.00 76.71  ? 233 PHE R C   1 
ATOM   8435 O O   . PHE E 5 771 ? 126.735 126.378 157.978 1.00 83.81  ? 233 PHE R O   1 
ATOM   8436 C CB  . PHE E 5 771 ? 124.516 125.352 155.735 1.00 55.30  ? 233 PHE R CB  1 
ATOM   8437 C CG  . PHE E 5 771 ? 123.689 126.040 156.775 1.00 64.36  ? 233 PHE R CG  1 
ATOM   8438 C CD1 . PHE E 5 771 ? 123.216 127.321 156.563 1.00 72.02  ? 233 PHE R CD1 1 
ATOM   8439 C CD2 . PHE E 5 771 ? 123.383 125.407 157.965 1.00 66.89  ? 233 PHE R CD2 1 
ATOM   8440 C CE1 . PHE E 5 771 ? 122.455 127.958 157.519 1.00 73.07  ? 233 PHE R CE1 1 
ATOM   8441 C CE2 . PHE E 5 771 ? 122.622 126.039 158.923 1.00 71.15  ? 233 PHE R CE2 1 
ATOM   8442 C CZ  . PHE E 5 771 ? 122.157 127.315 158.700 1.00 73.22  ? 233 PHE R CZ  1 
ATOM   8443 N N   . ILE E 5 772 ? 126.805 124.178 157.520 1.00 75.82  ? 234 ILE R N   1 
ATOM   8444 C CA  . ILE E 5 772 ? 127.323 123.852 158.846 1.00 67.67  ? 234 ILE R CA  1 
ATOM   8445 C C   . ILE E 5 772 ? 128.688 124.493 159.053 1.00 67.38  ? 234 ILE R C   1 
ATOM   8446 O O   . ILE E 5 772 ? 128.948 125.121 160.087 1.00 73.77  ? 234 ILE R O   1 
ATOM   8447 C CB  . ILE E 5 772 ? 127.377 122.328 159.044 1.00 70.56  ? 234 ILE R CB  1 
ATOM   8448 C CG1 . ILE E 5 772 ? 125.967 121.769 159.223 1.00 74.31  ? 234 ILE R CG1 1 
ATOM   8449 C CG2 . ILE E 5 772 ? 128.242 121.976 160.242 1.00 71.38  ? 234 ILE R CG2 1 
ATOM   8450 C CD1 . ILE E 5 772 ? 125.203 122.411 160.358 1.00 75.49  ? 234 ILE R CD1 1 
ATOM   8451 N N   . VAL E 5 773 ? 129.570 124.373 158.059 1.00 59.62  ? 235 VAL R N   1 
ATOM   8452 C CA  . VAL E 5 773 ? 130.915 124.921 158.194 1.00 58.65  ? 235 VAL R CA  1 
ATOM   8453 C C   . VAL E 5 773 ? 130.863 126.436 158.355 1.00 64.39  ? 235 VAL R C   1 
ATOM   8454 O O   . VAL E 5 773 ? 131.526 127.010 159.229 1.00 80.60  ? 235 VAL R O   1 
ATOM   8455 C CB  . VAL E 5 773 ? 131.780 124.507 156.992 1.00 61.32  ? 235 VAL R CB  1 
ATOM   8456 C CG1 . VAL E 5 773 ? 132.989 125.400 156.883 1.00 66.08  ? 235 VAL R CG1 1 
ATOM   8457 C CG2 . VAL E 5 773 ? 132.200 123.056 157.124 1.00 64.05  ? 235 VAL R CG2 1 
ATOM   8458 N N   . PHE E 5 774 ? 130.058 127.109 157.530 1.00 72.17  ? 236 PHE R N   1 
ATOM   8459 C CA  . PHE E 5 774 ? 130.048 128.566 157.566 1.00 75.71  ? 236 PHE R CA  1 
ATOM   8460 C C   . PHE E 5 774 ? 129.344 129.093 158.807 1.00 76.07  ? 236 PHE R C   1 
ATOM   8461 O O   . PHE E 5 774 ? 129.751 130.120 159.360 1.00 87.68  ? 236 PHE R O   1 
ATOM   8462 C CB  . PHE E 5 774 ? 129.402 129.131 156.308 1.00 71.31  ? 236 PHE R CB  1 
ATOM   8463 C CG  . PHE E 5 774 ? 129.738 130.569 156.064 1.00 75.45  ? 236 PHE R CG  1 
ATOM   8464 C CD1 . PHE E 5 774 ? 131.023 130.938 155.709 1.00 78.09  ? 236 PHE R CD1 1 
ATOM   8465 C CD2 . PHE E 5 774 ? 128.778 131.553 156.205 1.00 80.81  ? 236 PHE R CD2 1 
ATOM   8466 C CE1 . PHE E 5 774 ? 131.341 132.257 155.489 1.00 83.12  ? 236 PHE R CE1 1 
ATOM   8467 C CE2 . PHE E 5 774 ? 129.090 132.876 155.986 1.00 84.70  ? 236 PHE R CE2 1 
ATOM   8468 C CZ  . PHE E 5 774 ? 130.373 133.229 155.627 1.00 84.80  ? 236 PHE R CZ  1 
ATOM   8469 N N   . THR E 5 775 ? 128.289 128.418 159.266 1.00 58.25  ? 237 THR R N   1 
ATOM   8470 C CA  . THR E 5 775 ? 127.652 128.862 160.497 1.00 67.53  ? 237 THR R CA  1 
ATOM   8471 C C   . THR E 5 775 ? 128.546 128.604 161.701 1.00 78.28  ? 237 THR R C   1 
ATOM   8472 O O   . THR E 5 775 ? 128.532 129.389 162.653 1.00 80.24  ? 237 THR R O   1 
ATOM   8473 C CB  . THR E 5 775 ? 126.284 128.198 160.670 1.00 75.01  ? 237 THR R CB  1 
ATOM   8474 O OG1 . THR E 5 775 ? 125.501 128.960 161.596 1.00 86.06  ? 237 THR R OG1 1 
ATOM   8475 C CG2 . THR E 5 775 ? 126.411 126.770 161.183 1.00 78.56  ? 237 THR R CG2 1 
ATOM   8476 N N   . SER E 5 776 ? 129.363 127.547 161.664 1.00 84.31  ? 238 SER R N   1 
ATOM   8477 C CA  . SER E 5 776 ? 130.336 127.342 162.731 1.00 84.39  ? 238 SER R CA  1 
ATOM   8478 C C   . SER E 5 776 ? 131.406 128.427 162.714 1.00 84.62  ? 238 SER R C   1 
ATOM   8479 O O   . SER E 5 776 ? 131.817 128.918 163.772 1.00 91.61  ? 238 SER R O   1 
ATOM   8480 C CB  . SER E 5 776 ? 130.968 125.960 162.601 1.00 78.44  ? 238 SER R CB  1 
ATOM   8481 O OG  . SER E 5 776 ? 131.961 125.953 161.593 1.00 80.53  ? 238 SER R OG  1 
ATOM   8482 N N   . TYR E 5 777 ? 131.869 128.810 161.522 1.00 70.66  ? 239 TYR R N   1 
ATOM   8483 C CA  . TYR E 5 777 ? 132.830 129.903 161.421 1.00 58.84  ? 239 TYR R CA  1 
ATOM   8484 C C   . TYR E 5 777 ? 132.234 131.210 161.930 1.00 64.91  ? 239 TYR R C   1 
ATOM   8485 O O   . TYR E 5 777 ? 132.892 131.965 162.657 1.00 81.72  ? 239 TYR R O   1 
ATOM   8486 C CB  . TYR E 5 777 ? 133.295 130.052 159.975 1.00 64.40  ? 239 TYR R CB  1 
ATOM   8487 C CG  . TYR E 5 777 ? 134.257 131.190 159.745 1.00 71.15  ? 239 TYR R CG  1 
ATOM   8488 C CD1 . TYR E 5 777 ? 135.618 131.021 159.933 1.00 70.55  ? 239 TYR R CD1 1 
ATOM   8489 C CD2 . TYR E 5 777 ? 133.806 132.431 159.324 1.00 74.81  ? 239 TYR R CD2 1 
ATOM   8490 C CE1 . TYR E 5 777 ? 136.500 132.055 159.719 1.00 70.97  ? 239 TYR R CE1 1 
ATOM   8491 C CE2 . TYR E 5 777 ? 134.682 133.470 159.110 1.00 77.51  ? 239 TYR R CE2 1 
ATOM   8492 C CZ  . TYR E 5 777 ? 136.027 133.277 159.308 1.00 77.37  ? 239 TYR R CZ  1 
ATOM   8493 O OH  . TYR E 5 777 ? 136.905 134.314 159.093 1.00 82.00  ? 239 TYR R OH  1 
ATOM   8494 N N   . PHE E 5 778 ? 130.987 131.494 161.559 1.00 56.78  ? 240 PHE R N   1 
ATOM   8495 C CA  . PHE E 5 778 ? 130.332 132.703 162.042 1.00 60.10  ? 240 PHE R CA  1 
ATOM   8496 C C   . PHE E 5 778 ? 130.179 132.670 163.554 1.00 70.98  ? 240 PHE R C   1 
ATOM   8497 O O   . PHE E 5 778 ? 130.401 133.681 164.228 1.00 84.20  ? 240 PHE R O   1 
ATOM   8498 C CB  . PHE E 5 778 ? 128.974 132.871 161.365 1.00 63.96  ? 240 PHE R CB  1 
ATOM   8499 C CG  . PHE E 5 778 ? 128.189 134.045 161.866 1.00 61.09  ? 240 PHE R CG  1 
ATOM   8500 C CD1 . PHE E 5 778 ? 128.442 135.314 161.387 1.00 67.42  ? 240 PHE R CD1 1 
ATOM   8501 C CD2 . PHE E 5 778 ? 127.192 133.877 162.806 1.00 68.94  ? 240 PHE R CD2 1 
ATOM   8502 C CE1 . PHE E 5 778 ? 127.722 136.395 161.841 1.00 78.95  ? 240 PHE R CE1 1 
ATOM   8503 C CE2 . PHE E 5 778 ? 126.468 134.955 163.265 1.00 75.43  ? 240 PHE R CE2 1 
ATOM   8504 C CZ  . PHE E 5 778 ? 126.734 136.216 162.781 1.00 79.37  ? 240 PHE R CZ  1 
ATOM   8505 N N   . LEU E 5 779 ? 129.813 131.513 164.108 1.00 73.32  ? 241 LEU R N   1 
ATOM   8506 C CA  . LEU E 5 779 ? 129.653 131.403 165.552 1.00 77.76  ? 241 LEU R CA  1 
ATOM   8507 C C   . LEU E 5 779 ? 130.978 131.597 166.276 1.00 76.26  ? 241 LEU R C   1 
ATOM   8508 O O   . LEU E 5 779 ? 131.028 132.261 167.316 1.00 83.10  ? 241 LEU R O   1 
ATOM   8509 C CB  . LEU E 5 779 ? 129.036 130.052 165.909 1.00 79.78  ? 241 LEU R CB  1 
ATOM   8510 C CG  . LEU E 5 779 ? 127.520 129.953 165.730 1.00 80.90  ? 241 LEU R CG  1 
ATOM   8511 C CD1 . LEU E 5 779 ? 127.021 128.576 166.137 1.00 77.44  ? 241 LEU R CD1 1 
ATOM   8512 C CD2 . LEU E 5 779 ? 126.814 131.040 166.521 1.00 79.89  ? 241 LEU R CD2 1 
ATOM   8513 N N   . THR E 5 780 ? 132.066 131.031 165.749 1.00 75.02  ? 242 THR R N   1 
ATOM   8514 C CA  . THR E 5 780 ? 133.345 131.173 166.437 1.00 78.41  ? 242 THR R CA  1 
ATOM   8515 C C   . THR E 5 780 ? 133.869 132.603 166.339 1.00 84.69  ? 242 THR R C   1 
ATOM   8516 O O   . THR E 5 780 ? 134.424 133.132 167.313 1.00 90.87  ? 242 THR R O   1 
ATOM   8517 C CB  . THR E 5 780 ? 134.363 130.156 165.905 1.00 79.62  ? 242 THR R CB  1 
ATOM   8518 O OG1 . THR E 5 780 ? 135.542 130.188 166.715 1.00 80.13  ? 242 THR R OG1 1 
ATOM   8519 C CG2 . THR E 5 780 ? 134.747 130.431 164.474 1.00 81.05  ? 242 THR R CG2 1 
ATOM   8520 N N   . ILE E 5 781 ? 133.665 133.269 165.198 1.00 87.99  ? 243 ILE R N   1 
ATOM   8521 C CA  . ILE E 5 781 ? 134.074 134.669 165.113 1.00 82.99  ? 243 ILE R CA  1 
ATOM   8522 C C   . ILE E 5 781 ? 133.194 135.542 166.001 1.00 77.37  ? 243 ILE R C   1 
ATOM   8523 O O   . ILE E 5 781 ? 133.667 136.530 166.571 1.00 87.75  ? 243 ILE R O   1 
ATOM   8524 C CB  . ILE E 5 781 ? 134.075 135.158 163.655 1.00 77.44  ? 243 ILE R CB  1 
ATOM   8525 C CG1 . ILE E 5 781 ? 135.001 134.292 162.808 1.00 80.12  ? 243 ILE R CG1 1 
ATOM   8526 C CG2 . ILE E 5 781 ? 134.579 136.577 163.582 1.00 79.72  ? 243 ILE R CG2 1 
ATOM   8527 C CD1 . ILE E 5 781 ? 136.419 134.268 163.307 1.00 84.87  ? 243 ILE R CD1 1 
ATOM   8528 N N   . LEU E 5 782 ? 131.912 135.199 166.145 1.00 69.12  ? 244 LEU R N   1 
ATOM   8529 C CA  . LEU E 5 782 ? 131.047 135.934 167.062 1.00 70.17  ? 244 LEU R CA  1 
ATOM   8530 C C   . LEU E 5 782 ? 131.490 135.747 168.511 1.00 75.47  ? 244 LEU R C   1 
ATOM   8531 O O   . LEU E 5 782 ? 131.485 136.706 169.292 1.00 81.92  ? 244 LEU R O   1 
ATOM   8532 C CB  . LEU E 5 782 ? 129.599 135.483 166.855 1.00 76.72  ? 244 LEU R CB  1 
ATOM   8533 C CG  . LEU E 5 782 ? 128.375 136.242 167.387 1.00 85.49  ? 244 LEU R CG  1 
ATOM   8534 C CD1 . LEU E 5 782 ? 128.332 136.385 168.901 1.00 85.95  ? 244 LEU R CD1 1 
ATOM   8535 C CD2 . LEU E 5 782 ? 128.293 137.607 166.718 1.00 81.43  ? 244 LEU R CD2 1 
ATOM   8536 N N   . ILE E 5 783 ? 131.879 134.531 168.890 1.00 85.80  ? 245 ILE R N   1 
ATOM   8537 C CA  . ILE E 5 783 ? 132.383 134.320 170.243 1.00 86.49  ? 245 ILE R CA  1 
ATOM   8538 C C   . ILE E 5 783 ? 133.664 135.118 170.454 1.00 89.64  ? 245 ILE R C   1 
ATOM   8539 O O   . ILE E 5 783 ? 133.879 135.705 171.522 1.00 98.55  ? 245 ILE R O   1 
ATOM   8540 C CB  . ILE E 5 783 ? 132.587 132.819 170.522 1.00 91.22  ? 245 ILE R CB  1 
ATOM   8541 C CG1 . ILE E 5 783 ? 131.324 132.190 171.118 1.00 95.06  ? 245 ILE R CG1 1 
ATOM   8542 C CG2 . ILE E 5 783 ? 133.712 132.616 171.514 1.00 88.70  ? 245 ILE R CG2 1 
ATOM   8543 C CD1 . ILE E 5 783 ? 130.043 132.445 170.351 1.00 90.02  ? 245 ILE R CD1 1 
ATOM   8544 N N   . THR E 5 784 ? 134.526 135.169 169.433 1.00 79.44  ? 246 THR R N   1 
ATOM   8545 C CA  . THR E 5 784 ? 135.720 136.007 169.513 1.00 74.90  ? 246 THR R CA  1 
ATOM   8546 C C   . THR E 5 784 ? 135.354 137.476 169.696 1.00 71.44  ? 246 THR R C   1 
ATOM   8547 O O   . THR E 5 784 ? 135.969 138.183 170.502 1.00 76.44  ? 246 THR R O   1 
ATOM   8548 C CB  . THR E 5 784 ? 136.573 135.821 168.258 1.00 76.31  ? 246 THR R CB  1 
ATOM   8549 O OG1 . THR E 5 784 ? 137.224 134.547 168.306 1.00 84.96  ? 246 THR R OG1 1 
ATOM   8550 C CG2 . THR E 5 784 ? 137.622 136.912 168.152 1.00 73.64  ? 246 THR R CG2 1 
ATOM   8551 N N   . ILE E 5 785 ? 134.345 137.948 168.961 1.00 74.57  ? 247 ILE R N   1 
ATOM   8552 C CA  . ILE E 5 785 ? 133.904 139.334 169.082 1.00 68.83  ? 247 ILE R CA  1 
ATOM   8553 C C   . ILE E 5 785 ? 133.365 139.599 170.479 1.00 77.41  ? 247 ILE R C   1 
ATOM   8554 O O   . ILE E 5 785 ? 133.427 140.730 170.974 1.00 80.67  ? 247 ILE R O   1 
ATOM   8555 C CB  . ILE E 5 785 ? 132.855 139.654 167.998 1.00 79.07  ? 247 ILE R CB  1 
ATOM   8556 C CG1 . ILE E 5 785 ? 133.468 139.599 166.611 1.00 81.85  ? 247 ILE R CG1 1 
ATOM   8557 C CG2 . ILE E 5 785 ? 132.302 141.056 168.152 1.00 86.60  ? 247 ILE R CG2 1 
ATOM   8558 C CD1 . ILE E 5 785 ? 132.412 139.645 165.546 1.00 86.02  ? 247 ILE R CD1 1 
ATOM   8559 N N   . ILE E 5 786 ? 132.833 138.572 171.136 1.00 110.33 ? 248 ILE R N   1 
ATOM   8560 C CA  . ILE E 5 786 ? 132.409 138.679 172.524 1.00 113.66 ? 248 ILE R CA  1 
ATOM   8561 C C   . ILE E 5 786 ? 133.496 138.129 173.459 1.00 116.58 ? 248 ILE R C   1 
ATOM   8562 O O   . ILE E 5 786 ? 133.236 137.821 174.622 1.00 116.63 ? 248 ILE R O   1 
ATOM   8563 C CB  . ILE E 5 786 ? 131.044 137.996 172.737 1.00 112.36 ? 248 ILE R CB  1 
ATOM   8564 C CG1 . ILE E 5 786 ? 129.988 138.703 171.894 1.00 110.73 ? 248 ILE R CG1 1 
ATOM   8565 C CG2 . ILE E 5 786 ? 130.509 138.170 174.152 1.00 114.11 ? 248 ILE R CG2 1 
ATOM   8566 C CD1 . ILE E 5 786 ? 128.600 138.120 172.038 1.00 110.20 ? 248 ILE R CD1 1 
ATOM   8567 N N   . GLY E 5 787 ? 134.732 138.030 172.966 1.00 126.42 ? 249 GLY R N   1 
ATOM   8568 C CA  . GLY E 5 787 ? 135.825 137.514 173.772 1.00 125.90 ? 249 GLY R CA  1 
ATOM   8569 C C   . GLY E 5 787 ? 136.105 138.329 175.015 1.00 123.13 ? 249 GLY R C   1 
ATOM   8570 O O   . GLY E 5 787 ? 136.752 137.829 175.941 1.00 123.30 ? 249 GLY R O   1 
ATOM   8571 N N   . THR E 5 788 ? 135.634 139.577 175.056 1.00 133.99 ? 250 THR R N   1 
ATOM   8572 C CA  . THR E 5 788 ? 135.756 140.375 176.270 1.00 139.16 ? 250 THR R CA  1 
ATOM   8573 C C   . THR E 5 788 ? 134.990 139.746 177.425 1.00 140.57 ? 250 THR R C   1 
ATOM   8574 O O   . THR E 5 788 ? 135.424 139.835 178.580 1.00 138.99 ? 250 THR R O   1 
ATOM   8575 C CB  . THR E 5 788 ? 135.256 141.797 176.018 1.00 139.73 ? 250 THR R CB  1 
ATOM   8576 O OG1 . THR E 5 788 ? 133.848 141.769 175.758 1.00 140.26 ? 250 THR R OG1 1 
ATOM   8577 C CG2 . THR E 5 788 ? 135.973 142.409 174.824 1.00 138.26 ? 250 THR R CG2 1 
ATOM   8578 N N   . LEU E 5 789 ? 133.854 139.110 177.138 1.00 141.27 ? 251 LEU R N   1 
ATOM   8579 C CA  . LEU E 5 789 ? 133.038 138.457 178.152 1.00 141.19 ? 251 LEU R CA  1 
ATOM   8580 C C   . LEU E 5 789 ? 133.113 136.937 178.063 1.00 137.57 ? 251 LEU R C   1 
ATOM   8581 O O   . LEU E 5 789 ? 132.264 136.245 178.631 1.00 139.22 ? 251 LEU R O   1 
ATOM   8582 C CB  . LEU E 5 789 ? 131.586 138.922 178.043 1.00 140.69 ? 251 LEU R CB  1 
ATOM   8583 C CG  . LEU E 5 789 ? 131.336 140.418 178.244 1.00 140.30 ? 251 LEU R CG  1 
ATOM   8584 C CD1 . LEU E 5 789 ? 129.868 140.752 178.023 1.00 138.68 ? 251 LEU R CD1 1 
ATOM   8585 C CD2 . LEU E 5 789 ? 131.787 140.858 179.629 1.00 138.41 ? 251 LEU R CD2 1 
ATOM   8586 N N   . PHE E 5 790 ? 134.135 136.411 177.399 1.00 117.50 ? 252 PHE R N   1 
ATOM   8587 C CA  . PHE E 5 790 ? 134.257 134.983 177.120 1.00 114.38 ? 252 PHE R CA  1 
ATOM   8588 C C   . PHE E 5 790 ? 135.705 134.585 177.382 1.00 114.60 ? 252 PHE R C   1 
ATOM   8589 O O   . PHE E 5 790 ? 136.455 135.305 178.050 1.00 117.03 ? 252 PHE R O   1 
ATOM   8590 C CB  . PHE E 5 790 ? 133.798 134.661 175.689 1.00 116.55 ? 252 PHE R CB  1 
ATOM   8591 C CG  . PHE E 5 790 ? 132.340 134.937 175.437 1.00 120.79 ? 252 PHE R CG  1 
ATOM   8592 C CD1 . PHE E 5 790 ? 131.449 135.056 176.486 1.00 120.62 ? 252 PHE R CD1 1 
ATOM   8593 C CD2 . PHE E 5 790 ? 131.865 135.084 174.145 1.00 121.57 ? 252 PHE R CD2 1 
ATOM   8594 C CE1 . PHE E 5 790 ? 130.111 135.311 176.257 1.00 121.69 ? 252 PHE R CE1 1 
ATOM   8595 C CE2 . PHE E 5 790 ? 130.527 135.340 173.908 1.00 121.18 ? 252 PHE R CE2 1 
ATOM   8596 C CZ  . PHE E 5 790 ? 129.649 135.453 174.966 1.00 120.99 ? 252 PHE R CZ  1 
ATOM   8597 N N   . ASP E 5 791 ? 136.098 133.419 176.873 1.00 100.24 ? 253 ASP R N   1 
ATOM   8598 C CA  . ASP E 5 791 ? 137.424 132.882 177.150 1.00 103.49 ? 253 ASP R CA  1 
ATOM   8599 C C   . ASP E 5 791 ? 138.515 133.865 176.741 1.00 110.22 ? 253 ASP R C   1 
ATOM   8600 O O   . ASP E 5 791 ? 138.432 134.523 175.701 1.00 113.05 ? 253 ASP R O   1 
ATOM   8601 C CB  . ASP E 5 791 ? 137.611 131.547 176.427 1.00 104.00 ? 253 ASP R CB  1 
ATOM   8602 C CG  . ASP E 5 791 ? 138.092 131.717 175.001 1.00 110.84 ? 253 ASP R CG  1 
ATOM   8603 O OD1 . ASP E 5 791 ? 137.250 131.985 174.119 1.00 114.94 ? 253 ASP R OD1 1 
ATOM   8604 O OD2 . ASP E 5 791 ? 139.310 131.586 174.762 1.00 110.31 ? 253 ASP R OD2 1 
ATOM   8605 N N   . LYS E 5 792 ? 139.534 133.975 177.589 1.00 127.03 ? 254 LYS R N   1 
ATOM   8606 C CA  . LYS E 5 792 ? 140.607 134.935 177.385 1.00 126.64 ? 254 LYS R CA  1 
ATOM   8607 C C   . LYS E 5 792 ? 141.511 134.397 176.280 1.00 128.01 ? 254 LYS R C   1 
ATOM   8608 O O   . LYS E 5 792 ? 141.788 133.196 176.215 1.00 127.34 ? 254 LYS R O   1 
ATOM   8609 C CB  . LYS E 5 792 ? 141.351 135.148 178.715 1.00 124.58 ? 254 LYS R CB  1 
ATOM   8610 C CG  . LYS E 5 792 ? 142.509 136.166 178.854 1.00 125.51 ? 254 LYS R CG  1 
ATOM   8611 C CD  . LYS E 5 792 ? 143.103 136.281 180.258 1.00 127.41 ? 254 LYS R CD  1 
ATOM   8612 C CE  . LYS E 5 792 ? 144.247 137.277 180.319 1.00 128.27 ? 254 LYS R CE  1 
ATOM   8613 N NZ  . LYS E 5 792 ? 144.811 137.374 181.696 1.00 127.91 ? 254 LYS R NZ  1 
ATOM   8614 N N   . ARG E 5 793 ? 141.973 135.296 175.411 1.00 126.08 ? 255 ARG R N   1 
ATOM   8615 C CA  . ARG E 5 793 ? 142.710 134.935 174.204 1.00 126.44 ? 255 ARG R CA  1 
ATOM   8616 C C   . ARG E 5 793 ? 144.058 134.276 174.484 1.00 127.85 ? 255 ARG R C   1 
ATOM   8617 O O   . ARG E 5 793 ? 144.835 134.044 173.552 1.00 128.70 ? 255 ARG R O   1 
ATOM   8618 C CB  . ARG E 5 793 ? 142.918 136.176 173.335 1.00 124.41 ? 255 ARG R CB  1 
ATOM   8619 C CG  . ARG E 5 793 ? 141.644 136.950 173.055 1.00 123.45 ? 255 ARG R CG  1 
ATOM   8620 C CD  . ARG E 5 793 ? 140.734 136.186 172.098 1.00 123.37 ? 255 ARG R CD  1 
ATOM   8621 N NE  . ARG E 5 793 ? 141.414 135.665 170.916 1.00 125.25 ? 255 ARG R NE  1 
ATOM   8622 C CZ  . ARG E 5 793 ? 142.139 136.379 170.062 1.00 127.98 ? 255 ARG R CZ  1 
ATOM   8623 N NH1 . ARG E 5 793 ? 142.258 137.692 170.175 1.00 128.38 ? 255 ARG R NH1 1 
ATOM   8624 N NH2 . ARG E 5 793 ? 142.743 135.760 169.051 1.00 128.94 ? 255 ARG R NH2 1 
ATOM   8625 N N   . CYS E 5 794 ? 144.360 133.993 175.755 1.00 132.58 ? 256 CYS R N   1 
ATOM   8626 C CA  . CYS E 5 794 ? 145.569 133.239 176.076 1.00 132.83 ? 256 CYS R CA  1 
ATOM   8627 C C   . CYS E 5 794 ? 145.595 131.897 175.357 1.00 134.94 ? 256 CYS R C   1 
ATOM   8628 O O   . CYS E 5 794 ? 146.671 131.405 174.998 1.00 136.18 ? 256 CYS R O   1 
ATOM   8629 C CB  . CYS E 5 794 ? 145.674 133.030 177.587 1.00 133.43 ? 256 CYS R CB  1 
ATOM   8630 S SG  . CYS E 5 794 ? 146.991 131.902 178.104 1.00 138.56 ? 256 CYS R SG  1 
ATOM   8631 N N   . TRP E 5 795 ? 144.427 131.298 175.129 1.00 118.43 ? 257 TRP R N   1 
ATOM   8632 C CA  . TRP E 5 795 ? 144.328 130.091 174.320 1.00 114.42 ? 257 TRP R CA  1 
ATOM   8633 C C   . TRP E 5 795 ? 144.327 130.478 172.848 1.00 114.64 ? 257 TRP R C   1 
ATOM   8634 O O   . TRP E 5 795 ? 143.439 130.068 172.094 1.00 118.41 ? 257 TRP R O   1 
ATOM   8635 C CB  . TRP E 5 795 ? 143.061 129.289 174.650 1.00 116.27 ? 257 TRP R CB  1 
ATOM   8636 C CG  . TRP E 5 795 ? 142.688 129.152 176.114 1.00 117.38 ? 257 TRP R CG  1 
ATOM   8637 C CD1 . TRP E 5 795 ? 143.311 129.716 177.191 1.00 116.24 ? 257 TRP R CD1 1 
ATOM   8638 C CD2 . TRP E 5 795 ? 141.579 128.410 176.643 1.00 117.45 ? 257 TRP R CD2 1 
ATOM   8639 N NE1 . TRP E 5 795 ? 142.669 129.363 178.351 1.00 117.37 ? 257 TRP R NE1 1 
ATOM   8640 C CE2 . TRP E 5 795 ? 141.601 128.563 178.043 1.00 118.01 ? 257 TRP R CE2 1 
ATOM   8641 C CE3 . TRP E 5 795 ? 140.572 127.629 176.068 1.00 116.95 ? 257 TRP R CE3 1 
ATOM   8642 C CZ2 . TRP E 5 795 ? 140.658 127.964 178.875 1.00 118.12 ? 257 TRP R CZ2 1 
ATOM   8643 C CZ3 . TRP E 5 795 ? 139.636 127.035 176.896 1.00 115.37 ? 257 TRP R CZ3 1 
ATOM   8644 C CH2 . TRP E 5 795 ? 139.686 127.206 178.284 1.00 116.46 ? 257 TRP R CH2 1 
ATOM   8645 N N   . LEU E 5 796 ? 145.319 131.270 172.434 1.00 116.29 ? 258 LEU R N   1 
ATOM   8646 C CA  . LEU E 5 796 ? 145.321 131.820 171.083 1.00 114.69 ? 258 LEU R CA  1 
ATOM   8647 C C   . LEU E 5 796 ? 145.450 130.723 170.038 1.00 113.10 ? 258 LEU R C   1 
ATOM   8648 O O   . LEU E 5 796 ? 144.667 130.663 169.083 1.00 119.66 ? 258 LEU R O   1 
ATOM   8649 C CB  . LEU E 5 796 ? 146.455 132.835 170.935 1.00 116.74 ? 258 LEU R CB  1 
ATOM   8650 C CG  . LEU E 5 796 ? 146.551 133.566 169.596 1.00 117.23 ? 258 LEU R CG  1 
ATOM   8651 C CD1 . LEU E 5 796 ? 146.818 135.046 169.811 1.00 116.93 ? 258 LEU R CD1 1 
ATOM   8652 C CD2 . LEU E 5 796 ? 147.641 132.946 168.738 1.00 117.06 ? 258 LEU R CD2 1 
ATOM   8653 N N   . TRP E 5 797 ? 146.434 129.840 170.207 1.00 107.83 ? 259 TRP R N   1 
ATOM   8654 C CA  . TRP E 5 797 ? 146.712 128.849 169.176 1.00 117.00 ? 259 TRP R CA  1 
ATOM   8655 C C   . TRP E 5 797 ? 145.534 127.904 168.971 1.00 119.78 ? 259 TRP R C   1 
ATOM   8656 O O   . TRP E 5 797 ? 145.168 127.606 167.829 1.00 119.94 ? 259 TRP R O   1 
ATOM   8657 C CB  . TRP E 5 797 ? 147.981 128.077 169.529 1.00 117.40 ? 259 TRP R CB  1 
ATOM   8658 C CG  . TRP E 5 797 ? 149.210 128.936 169.527 1.00 115.90 ? 259 TRP R CG  1 
ATOM   8659 C CD1 . TRP E 5 797 ? 150.089 129.109 170.556 1.00 118.03 ? 259 TRP R CD1 1 
ATOM   8660 C CD2 . TRP E 5 797 ? 149.706 129.726 168.438 1.00 113.47 ? 259 TRP R CD2 1 
ATOM   8661 N NE1 . TRP E 5 797 ? 151.097 129.964 170.178 1.00 119.70 ? 259 TRP R NE1 1 
ATOM   8662 C CE2 . TRP E 5 797 ? 150.885 130.355 168.882 1.00 118.14 ? 259 TRP R CE2 1 
ATOM   8663 C CE3 . TRP E 5 797 ? 149.269 129.962 167.132 1.00 113.32 ? 259 TRP R CE3 1 
ATOM   8664 C CZ2 . TRP E 5 797 ? 151.629 131.206 168.068 1.00 119.32 ? 259 TRP R CZ2 1 
ATOM   8665 C CZ3 . TRP E 5 797 ? 150.009 130.807 166.327 1.00 115.64 ? 259 TRP R CZ3 1 
ATOM   8666 C CH2 . TRP E 5 797 ? 151.175 131.418 166.796 1.00 118.74 ? 259 TRP R CH2 1 
ATOM   8667 N N   . VAL E 5 798 ? 144.912 127.439 170.056 1.00 112.62 ? 260 VAL R N   1 
ATOM   8668 C CA  . VAL E 5 798 ? 143.830 126.469 169.912 1.00 110.80 ? 260 VAL R CA  1 
ATOM   8669 C C   . VAL E 5 798 ? 142.614 127.106 169.241 1.00 107.11 ? 260 VAL R C   1 
ATOM   8670 O O   . VAL E 5 798 ? 142.008 126.514 168.337 1.00 109.30 ? 260 VAL R O   1 
ATOM   8671 C CB  . VAL E 5 798 ? 143.491 125.830 171.277 1.00 112.14 ? 260 VAL R CB  1 
ATOM   8672 C CG1 . VAL E 5 798 ? 144.765 125.465 172.014 1.00 112.25 ? 260 VAL R CG1 1 
ATOM   8673 C CG2 . VAL E 5 798 ? 142.638 126.742 172.146 1.00 111.20 ? 260 VAL R CG2 1 
ATOM   8674 N N   . TRP E 5 799 ? 142.254 128.328 169.642 1.00 83.64  ? 261 TRP R N   1 
ATOM   8675 C CA  . TRP E 5 799 ? 141.100 128.987 169.042 1.00 76.42  ? 261 TRP R CA  1 
ATOM   8676 C C   . TRP E 5 799 ? 141.349 129.312 167.579 1.00 82.22  ? 261 TRP R C   1 
ATOM   8677 O O   . TRP E 5 799 ? 140.467 129.122 166.732 1.00 98.84  ? 261 TRP R O   1 
ATOM   8678 C CB  . TRP E 5 799 ? 140.758 130.255 169.814 1.00 76.54  ? 261 TRP R CB  1 
ATOM   8679 C CG  . TRP E 5 799 ? 139.407 130.768 169.497 1.00 74.34  ? 261 TRP R CG  1 
ATOM   8680 C CD1 . TRP E 5 799 ? 139.102 131.820 168.692 1.00 81.34  ? 261 TRP R CD1 1 
ATOM   8681 C CD2 . TRP E 5 799 ? 138.163 130.242 169.962 1.00 83.66  ? 261 TRP R CD2 1 
ATOM   8682 N NE1 . TRP E 5 799 ? 137.743 131.992 168.632 1.00 86.17  ? 261 TRP R NE1 1 
ATOM   8683 C CE2 . TRP E 5 799 ? 137.143 131.033 169.406 1.00 83.62  ? 261 TRP R CE2 1 
ATOM   8684 C CE3 . TRP E 5 799 ? 137.812 129.181 170.802 1.00 92.62  ? 261 TRP R CE3 1 
ATOM   8685 C CZ2 . TRP E 5 799 ? 135.798 130.797 169.656 1.00 87.36  ? 261 TRP R CZ2 1 
ATOM   8686 C CZ3 . TRP E 5 799 ? 136.474 128.949 171.051 1.00 93.37  ? 261 TRP R CZ3 1 
ATOM   8687 C CH2 . TRP E 5 799 ? 135.483 129.754 170.481 1.00 92.59  ? 261 TRP R CH2 1 
ATOM   8688 N N   . GLU E 5 800 ? 142.544 129.811 167.267 1.00 103.90 ? 262 GLU R N   1 
ATOM   8689 C CA  . GLU E 5 800 ? 142.870 130.118 165.883 1.00 109.42 ? 262 GLU R CA  1 
ATOM   8690 C C   . GLU E 5 800 ? 142.865 128.855 165.028 1.00 115.88 ? 262 GLU R C   1 
ATOM   8691 O O   . GLU E 5 800 ? 142.379 128.866 163.890 1.00 117.70 ? 262 GLU R O   1 
ATOM   8692 C CB  . GLU E 5 800 ? 144.222 130.825 165.822 1.00 105.93 ? 262 GLU R CB  1 
ATOM   8693 C CG  . GLU E 5 800 ? 144.255 132.198 166.474 1.00 114.63 ? 262 GLU R CG  1 
ATOM   8694 C CD  . GLU E 5 800 ? 143.184 133.126 165.947 1.00 118.56 ? 262 GLU R CD  1 
ATOM   8695 O OE1 . GLU E 5 800 ? 142.960 133.133 164.719 1.00 115.11 ? 262 GLU R OE1 1 
ATOM   8696 O OE2 . GLU E 5 800 ? 142.567 133.851 166.758 1.00 122.11 ? 262 GLU R OE2 1 
ATOM   8697 N N   . ALA E 5 801 ? 143.387 127.749 165.568 1.00 106.58 ? 263 ALA R N   1 
ATOM   8698 C CA  . ALA E 5 801 ? 143.364 126.486 164.841 1.00 102.69 ? 263 ALA R CA  1 
ATOM   8699 C C   . ALA E 5 801 ? 141.937 126.020 164.593 1.00 98.78  ? 263 ALA R C   1 
ATOM   8700 O O   . ALA E 5 801 ? 141.622 125.525 163.509 1.00 100.43 ? 263 ALA R O   1 
ATOM   8701 C CB  . ALA E 5 801 ? 144.152 125.427 165.609 1.00 103.33 ? 263 ALA R CB  1 
ATOM   8702 N N   . PHE E 5 802 ? 141.059 126.174 165.584 1.00 87.24  ? 264 PHE R N   1 
ATOM   8703 C CA  . PHE E 5 802 ? 139.650 125.840 165.396 1.00 88.42  ? 264 PHE R CA  1 
ATOM   8704 C C   . PHE E 5 802 ? 139.036 126.655 164.260 1.00 93.56  ? 264 PHE R C   1 
ATOM   8705 O O   . PHE E 5 802 ? 138.433 126.101 163.324 1.00 97.24  ? 264 PHE R O   1 
ATOM   8706 C CB  . PHE E 5 802 ? 138.902 126.088 166.706 1.00 85.57  ? 264 PHE R CB  1 
ATOM   8707 C CG  . PHE E 5 802 ? 137.611 125.345 166.826 1.00 83.82  ? 264 PHE R CG  1 
ATOM   8708 C CD1 . PHE E 5 802 ? 137.577 123.968 166.731 1.00 91.07  ? 264 PHE R CD1 1 
ATOM   8709 C CD2 . PHE E 5 802 ? 136.432 126.026 167.066 1.00 85.02  ? 264 PHE R CD2 1 
ATOM   8710 C CE1 . PHE E 5 802 ? 136.386 123.283 166.850 1.00 94.17  ? 264 PHE R CE1 1 
ATOM   8711 C CE2 . PHE E 5 802 ? 135.241 125.349 167.190 1.00 91.22  ? 264 PHE R CE2 1 
ATOM   8712 C CZ  . PHE E 5 802 ? 135.216 123.975 167.081 1.00 95.23  ? 264 PHE R CZ  1 
ATOM   8713 N N   . VAL E 5 803 ? 139.202 127.978 164.320 1.00 84.65  ? 265 VAL R N   1 
ATOM   8714 C CA  . VAL E 5 803 ? 138.578 128.861 163.338 1.00 80.56  ? 265 VAL R CA  1 
ATOM   8715 C C   . VAL E 5 803 ? 139.075 128.535 161.938 1.00 91.30  ? 265 VAL R C   1 
ATOM   8716 O O   . VAL E 5 803 ? 138.294 128.421 160.982 1.00 101.52 ? 265 VAL R O   1 
ATOM   8717 C CB  . VAL E 5 803 ? 138.848 130.332 163.696 1.00 86.23  ? 265 VAL R CB  1 
ATOM   8718 C CG1 . VAL E 5 803 ? 138.288 131.244 162.627 1.00 90.36  ? 265 VAL R CG1 1 
ATOM   8719 C CG2 . VAL E 5 803 ? 138.258 130.669 165.048 1.00 95.91  ? 265 VAL R CG2 1 
ATOM   8720 N N   . TYR E 5 804 ? 140.381 128.363 161.789 1.00 91.95  ? 266 TYR R N   1 
ATOM   8721 C CA  . TYR E 5 804 ? 140.902 128.166 160.450 1.00 94.55  ? 266 TYR R CA  1 
ATOM   8722 C C   . TYR E 5 804 ? 140.847 126.717 159.992 1.00 98.36  ? 266 TYR R C   1 
ATOM   8723 O O   . TYR E 5 804 ? 140.955 126.470 158.792 1.00 99.15  ? 266 TYR R O   1 
ATOM   8724 C CB  . TYR E 5 804 ? 142.307 128.757 160.358 1.00 89.65  ? 266 TYR R CB  1 
ATOM   8725 C CG  . TYR E 5 804 ? 142.204 130.257 160.454 1.00 87.26  ? 266 TYR R CG  1 
ATOM   8726 C CD1 . TYR E 5 804 ? 141.900 131.018 159.339 1.00 91.00  ? 266 TYR R CD1 1 
ATOM   8727 C CD2 . TYR E 5 804 ? 142.320 130.902 161.671 1.00 95.05  ? 266 TYR R CD2 1 
ATOM   8728 C CE1 . TYR E 5 804 ? 141.766 132.382 159.424 1.00 95.63  ? 266 TYR R CE1 1 
ATOM   8729 C CE2 . TYR E 5 804 ? 142.187 132.264 161.768 1.00 98.68  ? 266 TYR R CE2 1 
ATOM   8730 C CZ  . TYR E 5 804 ? 141.907 132.999 160.643 1.00 99.56  ? 266 TYR R CZ  1 
ATOM   8731 O OH  . TYR E 5 804 ? 141.774 134.363 160.742 1.00 104.77 ? 266 TYR R OH  1 
ATOM   8732 N N   . ALA E 5 805 ? 140.577 125.766 160.886 1.00 94.66  ? 267 ALA R N   1 
ATOM   8733 C CA  . ALA E 5 805 ? 140.133 124.454 160.433 1.00 92.48  ? 267 ALA R CA  1 
ATOM   8734 C C   . ALA E 5 805 ? 138.743 124.543 159.822 1.00 88.38  ? 267 ALA R C   1 
ATOM   8735 O O   . ALA E 5 805 ? 138.469 123.919 158.787 1.00 93.13  ? 267 ALA R O   1 
ATOM   8736 C CB  . ALA E 5 805 ? 140.154 123.458 161.591 1.00 95.37  ? 267 ALA R CB  1 
ATOM   8737 N N   . PHE E 5 806 ? 137.855 125.326 160.440 1.00 74.30  ? 268 PHE R N   1 
ATOM   8738 C CA  . PHE E 5 806 ? 136.555 125.571 159.820 1.00 73.84  ? 268 PHE R CA  1 
ATOM   8739 C C   . PHE E 5 806 ? 136.721 126.210 158.445 1.00 83.28  ? 268 PHE R C   1 
ATOM   8740 O O   . PHE E 5 806 ? 136.091 125.789 157.464 1.00 96.00  ? 268 PHE R O   1 
ATOM   8741 C CB  . PHE E 5 806 ? 135.693 126.458 160.716 1.00 75.72  ? 268 PHE R CB  1 
ATOM   8742 C CG  . PHE E 5 806 ? 135.007 125.718 161.819 1.00 73.39  ? 268 PHE R CG  1 
ATOM   8743 C CD1 . PHE E 5 806 ? 134.652 124.395 161.663 1.00 73.70  ? 268 PHE R CD1 1 
ATOM   8744 C CD2 . PHE E 5 806 ? 134.714 126.347 163.013 1.00 79.07  ? 268 PHE R CD2 1 
ATOM   8745 C CE1 . PHE E 5 806 ? 134.020 123.710 162.676 1.00 80.40  ? 268 PHE R CE1 1 
ATOM   8746 C CE2 . PHE E 5 806 ? 134.083 125.668 164.030 1.00 80.29  ? 268 PHE R CE2 1 
ATOM   8747 C CZ  . PHE E 5 806 ? 133.736 124.347 163.861 1.00 81.69  ? 268 PHE R CZ  1 
ATOM   8748 N N   . ILE E 5 807 ? 137.580 127.228 158.353 1.00 84.01  ? 269 ILE R N   1 
ATOM   8749 C CA  . ILE E 5 807 ? 137.749 127.903 157.068 1.00 78.93  ? 269 ILE R CA  1 
ATOM   8750 C C   . ILE E 5 807 ? 138.435 126.986 156.055 1.00 84.60  ? 269 ILE R C   1 
ATOM   8751 O O   . ILE E 5 807 ? 138.173 127.081 154.850 1.00 91.02  ? 269 ILE R O   1 
ATOM   8752 C CB  . ILE E 5 807 ? 138.498 129.238 157.240 1.00 83.66  ? 269 ILE R CB  1 
ATOM   8753 C CG1 . ILE E 5 807 ? 138.038 130.237 156.182 1.00 88.83  ? 269 ILE R CG1 1 
ATOM   8754 C CG2 . ILE E 5 807 ? 139.993 129.054 157.105 1.00 90.11  ? 269 ILE R CG2 1 
ATOM   8755 C CD1 . ILE E 5 807 ? 138.427 131.662 156.485 1.00 91.62  ? 269 ILE R CD1 1 
ATOM   8756 N N   . LEU E 5 808 ? 139.304 126.079 156.513 1.00 85.45  ? 270 LEU R N   1 
ATOM   8757 C CA  . LEU E 5 808 ? 139.910 125.107 155.611 1.00 86.91  ? 270 LEU R CA  1 
ATOM   8758 C C   . LEU E 5 808 ? 138.868 124.152 155.050 1.00 87.11  ? 270 LEU R C   1 
ATOM   8759 O O   . LEU E 5 808 ? 138.899 123.820 153.859 1.00 86.18  ? 270 LEU R O   1 
ATOM   8760 C CB  . LEU E 5 808 ? 141.009 124.333 156.339 1.00 87.10  ? 270 LEU R CB  1 
ATOM   8761 C CG  . LEU E 5 808 ? 141.643 123.166 155.582 1.00 91.58  ? 270 LEU R CG  1 
ATOM   8762 C CD1 . LEU E 5 808 ? 142.186 123.619 154.237 1.00 90.52  ? 270 LEU R CD1 1 
ATOM   8763 C CD2 . LEU E 5 808 ? 142.738 122.521 156.415 1.00 91.29  ? 270 LEU R CD2 1 
ATOM   8764 N N   . MET E 5 809 ? 137.943 123.691 155.894 1.00 91.69  ? 271 MET R N   1 
ATOM   8765 C CA  . MET E 5 809 ? 136.866 122.842 155.394 1.00 91.11  ? 271 MET R CA  1 
ATOM   8766 C C   . MET E 5 809 ? 136.005 123.593 154.388 1.00 91.78  ? 271 MET R C   1 
ATOM   8767 O O   . MET E 5 809 ? 135.600 123.029 153.365 1.00 98.00  ? 271 MET R O   1 
ATOM   8768 C CB  . MET E 5 809 ? 136.015 122.318 156.549 1.00 92.10  ? 271 MET R CB  1 
ATOM   8769 C CG  . MET E 5 809 ? 136.412 120.927 157.013 1.00 101.22 ? 271 MET R CG  1 
ATOM   8770 S SD  . MET E 5 809 ? 135.506 120.371 158.467 1.00 116.43 ? 271 MET R SD  1 
ATOM   8771 C CE  . MET E 5 809 ? 135.270 121.920 159.328 1.00 99.33  ? 271 MET R CE  1 
ATOM   8772 N N   . HIS E 5 810 ? 135.724 124.869 154.657 1.00 83.39  ? 272 HIS R N   1 
ATOM   8773 C CA  . HIS E 5 810 ? 134.966 125.677 153.703 1.00 79.29  ? 272 HIS R CA  1 
ATOM   8774 C C   . HIS E 5 810 ? 135.694 125.783 152.365 1.00 84.44  ? 272 HIS R C   1 
ATOM   8775 O O   . HIS E 5 810 ? 135.092 125.617 151.293 1.00 94.74  ? 272 HIS R O   1 
ATOM   8776 C CB  . HIS E 5 810 ? 134.719 127.066 154.287 1.00 81.49  ? 272 HIS R CB  1 
ATOM   8777 C CG  . HIS E 5 810 ? 133.604 127.811 153.628 1.00 83.06  ? 272 HIS R CG  1 
ATOM   8778 N ND1 . HIS E 5 810 ? 133.779 128.547 152.477 1.00 87.61  ? 272 HIS R ND1 1 
ATOM   8779 C CD2 . HIS E 5 810 ? 132.300 127.943 153.964 1.00 85.83  ? 272 HIS R CD2 1 
ATOM   8780 C CE1 . HIS E 5 810 ? 132.631 129.097 152.130 1.00 89.85  ? 272 HIS R CE1 1 
ATOM   8781 N NE2 . HIS E 5 810 ? 131.716 128.746 153.015 1.00 89.44  ? 272 HIS R NE2 1 
ATOM   8782 N N   . SER E 5 811 ? 137.000 126.052 152.412 1.00 83.46  ? 273 SER R N   1 
ATOM   8783 C CA  . SER E 5 811 ? 137.769 126.219 151.184 1.00 80.66  ? 273 SER R CA  1 
ATOM   8784 C C   . SER E 5 811 ? 137.864 124.913 150.407 1.00 91.47  ? 273 SER R C   1 
ATOM   8785 O O   . SER E 5 811 ? 137.821 124.918 149.175 1.00 94.65  ? 273 SER R O   1 
ATOM   8786 C CB  . SER E 5 811 ? 139.160 126.757 151.502 1.00 83.01  ? 273 SER R CB  1 
ATOM   8787 O OG  . SER E 5 811 ? 139.909 126.954 150.317 1.00 80.24  ? 273 SER R OG  1 
ATOM   8788 N N   . THR E 5 812 ? 137.987 123.783 151.105 1.00 96.68  ? 274 THR R N   1 
ATOM   8789 C CA  . THR E 5 812 ? 138.023 122.494 150.419 1.00 89.47  ? 274 THR R CA  1 
ATOM   8790 C C   . THR E 5 812 ? 136.664 122.148 149.815 1.00 87.40  ? 274 THR R C   1 
ATOM   8791 O O   . THR E 5 812 ? 136.587 121.569 148.722 1.00 95.08  ? 274 THR R O   1 
ATOM   8792 C CB  . THR E 5 812 ? 138.488 121.406 151.389 1.00 97.59  ? 274 THR R CB  1 
ATOM   8793 O OG1 . THR E 5 812 ? 139.890 121.564 151.639 1.00 97.73  ? 274 THR R OG1 1 
ATOM   8794 C CG2 . THR E 5 812 ? 138.242 120.019 150.814 1.00 95.19  ? 274 THR R CG2 1 
ATOM   8795 N N   . SER E 5 813 ? 135.577 122.497 150.507 1.00 78.93  ? 275 SER R N   1 
ATOM   8796 C CA  . SER E 5 813 ? 134.253 122.287 149.936 1.00 79.70  ? 275 SER R CA  1 
ATOM   8797 C C   . SER E 5 813 ? 134.083 123.085 148.651 1.00 81.24  ? 275 SER R C   1 
ATOM   8798 O O   . SER E 5 813 ? 133.561 122.571 147.654 1.00 91.49  ? 275 SER R O   1 
ATOM   8799 C CB  . SER E 5 813 ? 133.177 122.666 150.952 1.00 81.36  ? 275 SER R CB  1 
ATOM   8800 O OG  . SER E 5 813 ? 131.894 122.679 150.354 1.00 85.29  ? 275 SER R OG  1 
ATOM   8801 N N   . LEU E 5 814 ? 134.535 124.340 148.647 1.00 77.81  ? 276 LEU R N   1 
ATOM   8802 C CA  . LEU E 5 814 ? 134.428 125.135 147.426 1.00 82.81  ? 276 LEU R CA  1 
ATOM   8803 C C   . LEU E 5 814 ? 135.435 124.692 146.369 1.00 82.00  ? 276 LEU R C   1 
ATOM   8804 O O   . LEU E 5 814 ? 135.222 124.926 145.174 1.00 86.19  ? 276 LEU R O   1 
ATOM   8805 C CB  . LEU E 5 814 ? 134.587 126.615 147.750 1.00 83.94  ? 276 LEU R CB  1 
ATOM   8806 C CG  . LEU E 5 814 ? 133.468 127.107 148.664 1.00 85.45  ? 276 LEU R CG  1 
ATOM   8807 C CD1 . LEU E 5 814 ? 133.544 128.600 148.835 1.00 86.47  ? 276 LEU R CD1 1 
ATOM   8808 C CD2 . LEU E 5 814 ? 132.114 126.699 148.111 1.00 85.98  ? 276 LEU R CD2 1 
ATOM   8809 N N   . MET E 5 815 ? 136.538 124.071 146.788 1.00 96.90  ? 277 MET R N   1 
ATOM   8810 C CA  . MET E 5 815 ? 137.401 123.350 145.858 1.00 100.85 ? 277 MET R CA  1 
ATOM   8811 C C   . MET E 5 815 ? 136.630 122.280 145.107 1.00 102.67 ? 277 MET R C   1 
ATOM   8812 O O   . MET E 5 815 ? 136.630 122.242 143.872 1.00 102.53 ? 277 MET R O   1 
ATOM   8813 C CB  . MET E 5 815 ? 138.565 122.718 146.628 1.00 106.09 ? 277 MET R CB  1 
ATOM   8814 C CG  . MET E 5 815 ? 139.856 123.518 146.774 1.00 105.14 ? 277 MET R CG  1 
ATOM   8815 S SD  . MET E 5 815 ? 140.410 124.685 145.512 1.00 116.82 ? 277 MET R SD  1 
ATOM   8816 C CE  . MET E 5 815 ? 139.951 123.858 143.984 1.00 101.52 ? 277 MET R CE  1 
ATOM   8817 N N   . LEU E 5 816 ? 135.958 121.403 145.845 1.00 105.35 ? 278 LEU R N   1 
ATOM   8818 C CA  . LEU E 5 816 ? 135.214 120.327 145.209 1.00 103.67 ? 278 LEU R CA  1 
ATOM   8819 C C   . LEU E 5 816 ? 133.959 120.823 144.505 1.00 101.79 ? 278 LEU R C   1 
ATOM   8820 O O   . LEU E 5 816 ? 133.383 120.080 143.704 1.00 105.72 ? 278 LEU R O   1 
ATOM   8821 C CB  . LEU E 5 816 ? 134.862 119.258 146.243 1.00 108.61 ? 278 LEU R CB  1 
ATOM   8822 C CG  . LEU E 5 816 ? 136.084 118.651 146.937 1.00 106.40 ? 278 LEU R CG  1 
ATOM   8823 C CD1 . LEU E 5 816 ? 135.685 117.471 147.811 1.00 106.84 ? 278 LEU R CD1 1 
ATOM   8824 C CD2 . LEU E 5 816 ? 137.149 118.251 145.923 1.00 102.46 ? 278 LEU R CD2 1 
ATOM   8825 N N   . SER E 5 817 ? 133.528 122.052 144.779 1.00 99.86  ? 279 SER R N   1 
ATOM   8826 C CA  . SER E 5 817 ? 132.362 122.635 144.132 1.00 102.19 ? 279 SER R CA  1 
ATOM   8827 C C   . SER E 5 817 ? 132.708 123.492 142.921 1.00 108.02 ? 279 SER R C   1 
ATOM   8828 O O   . SER E 5 817 ? 131.814 124.136 142.365 1.00 113.90 ? 279 SER R O   1 
ATOM   8829 C CB  . SER E 5 817 ? 131.568 123.475 145.138 1.00 105.12 ? 279 SER R CB  1 
ATOM   8830 O OG  . SER E 5 817 ? 131.858 124.854 144.991 1.00 108.06 ? 279 SER R OG  1 
ATOM   8831 N N   . SER E 5 818 ? 133.968 123.533 142.507 1.00 109.44 ? 280 SER R N   1 
ATOM   8832 C CA  . SER E 5 818 ? 134.356 124.361 141.370 1.00 110.74 ? 280 SER R CA  1 
ATOM   8833 C C   . SER E 5 818 ? 134.279 123.551 140.082 1.00 107.58 ? 280 SER R C   1 
ATOM   8834 O O   . SER E 5 818 ? 134.963 122.528 139.967 1.00 108.69 ? 280 SER R O   1 
ATOM   8835 C CB  . SER E 5 818 ? 135.764 124.906 141.559 1.00 111.21 ? 280 SER R CB  1 
ATOM   8836 O OG  . SER E 5 818 ? 136.396 125.114 140.309 1.00 111.69 ? 280 SER R OG  1 
ATOM   8837 N N   . PRO E 5 819 ? 133.477 123.964 139.099 1.00 110.88 ? 281 PRO R N   1 
ATOM   8838 C CA  . PRO E 5 819 ? 133.351 123.172 137.868 1.00 113.70 ? 281 PRO R CA  1 
ATOM   8839 C C   . PRO E 5 819 ? 134.564 123.284 136.960 1.00 112.51 ? 281 PRO R C   1 
ATOM   8840 O O   . PRO E 5 819 ? 134.970 122.301 136.331 1.00 114.52 ? 281 PRO R O   1 
ATOM   8841 C CB  . PRO E 5 819 ? 132.102 123.762 137.203 1.00 110.78 ? 281 PRO R CB  1 
ATOM   8842 C CG  . PRO E 5 819 ? 132.064 125.164 137.677 1.00 110.03 ? 281 PRO R CG  1 
ATOM   8843 C CD  . PRO E 5 819 ? 132.630 125.167 139.073 1.00 111.90 ? 281 PRO R CD  1 
ATOM   8844 N N   . THR E 5 820 ? 135.147 124.480 136.876 1.00 103.30 ? 282 THR R N   1 
ATOM   8845 C CA  . THR E 5 820 ? 136.298 124.675 136.001 1.00 102.80 ? 282 THR R CA  1 
ATOM   8846 C C   . THR E 5 820 ? 137.497 123.862 136.470 1.00 106.00 ? 282 THR R C   1 
ATOM   8847 O O   . THR E 5 820 ? 138.219 123.287 135.650 1.00 113.87 ? 282 THR R O   1 
ATOM   8848 C CB  . THR E 5 820 ? 136.650 126.158 135.920 1.00 103.28 ? 282 THR R CB  1 
ATOM   8849 O OG1 . THR E 5 820 ? 135.622 126.847 135.200 1.00 102.60 ? 282 THR R OG1 1 
ATOM   8850 C CG2 . THR E 5 820 ? 137.973 126.360 135.202 1.00 105.33 ? 282 THR R CG2 1 
ATOM   8851 N N   . LEU E 5 821 ? 137.727 123.801 137.783 1.00 97.16  ? 283 LEU R N   1 
ATOM   8852 C CA  . LEU E 5 821 ? 138.882 123.066 138.285 1.00 98.96  ? 283 LEU R CA  1 
ATOM   8853 C C   . LEU E 5 821 ? 138.766 121.580 137.966 1.00 105.03 ? 283 LEU R C   1 
ATOM   8854 O O   . LEU E 5 821 ? 139.736 120.961 137.513 1.00 110.41 ? 283 LEU R O   1 
ATOM   8855 C CB  . LEU E 5 821 ? 139.036 123.301 139.790 1.00 102.10 ? 283 LEU R CB  1 
ATOM   8856 C CG  . LEU E 5 821 ? 140.334 122.967 140.545 1.00 104.73 ? 283 LEU R CG  1 
ATOM   8857 C CD1 . LEU E 5 821 ? 140.743 121.496 140.504 1.00 101.95 ? 283 LEU R CD1 1 
ATOM   8858 C CD2 . LEU E 5 821 ? 141.469 123.845 140.038 1.00 106.53 ? 283 LEU R CD2 1 
ATOM   8859 N N   . LYS E 5 822 ? 137.589 120.989 138.182 1.00 105.09 ? 284 LYS R N   1 
ATOM   8860 C CA  . LYS E 5 822 ? 137.430 119.568 137.892 1.00 106.23 ? 284 LYS R CA  1 
ATOM   8861 C C   . LYS E 5 822 ? 137.433 119.308 136.391 1.00 107.80 ? 284 LYS R C   1 
ATOM   8862 O O   . LYS E 5 822 ? 137.936 118.273 135.938 1.00 108.60 ? 284 LYS R O   1 
ATOM   8863 C CB  . LYS E 5 822 ? 136.149 119.032 138.532 1.00 107.58 ? 284 LYS R CB  1 
ATOM   8864 C CG  . LYS E 5 822 ? 134.915 119.865 138.262 1.00 108.02 ? 284 LYS R CG  1 
ATOM   8865 C CD  . LYS E 5 822 ? 133.681 118.993 138.105 1.00 109.87 ? 284 LYS R CD  1 
ATOM   8866 C CE  . LYS E 5 822 ? 133.227 118.440 139.444 1.00 109.64 ? 284 LYS R CE  1 
ATOM   8867 N NZ  . LYS E 5 822 ? 133.051 119.520 140.451 1.00 109.91 ? 284 LYS R NZ  1 
ATOM   8868 N N   . ARG E 5 823 ? 136.875 120.231 135.603 1.00 113.89 ? 285 ARG R N   1 
ATOM   8869 C CA  . ARG E 5 823 ? 136.893 120.068 134.153 1.00 113.25 ? 285 ARG R CA  1 
ATOM   8870 C C   . ARG E 5 823 ? 138.317 120.105 133.613 1.00 111.74 ? 285 ARG R C   1 
ATOM   8871 O O   . ARG E 5 823 ? 138.683 119.300 132.749 1.00 116.21 ? 285 ARG R O   1 
ATOM   8872 C CB  . ARG E 5 823 ? 136.037 121.150 133.495 1.00 111.95 ? 285 ARG R CB  1 
ATOM   8873 C CG  . ARG E 5 823 ? 136.265 121.305 132.002 1.00 110.95 ? 285 ARG R CG  1 
ATOM   8874 C CD  . ARG E 5 823 ? 135.098 122.030 131.337 1.00 112.55 ? 285 ARG R CD  1 
ATOM   8875 N NE  . ARG E 5 823 ? 135.252 123.481 131.250 1.00 114.97 ? 285 ARG R NE  1 
ATOM   8876 C CZ  . ARG E 5 823 ? 136.308 124.126 130.767 1.00 116.46 ? 285 ARG R CZ  1 
ATOM   8877 N NH1 . ARG E 5 823 ? 137.329 123.484 130.220 1.00 116.45 ? 285 ARG R NH1 1 
ATOM   8878 N NH2 . ARG E 5 823 ? 136.329 125.455 130.808 1.00 115.91 ? 285 ARG R NH2 1 
ATOM   8879 N N   . ILE E 5 824 ? 139.136 121.031 134.112 1.00 101.47 ? 286 ILE R N   1 
ATOM   8880 C CA  . ILE E 5 824 ? 140.519 121.122 133.660 1.00 103.06 ? 286 ILE R CA  1 
ATOM   8881 C C   . ILE E 5 824 ? 141.324 119.930 134.162 1.00 104.91 ? 286 ILE R C   1 
ATOM   8882 O O   . ILE E 5 824 ? 142.096 119.323 133.410 1.00 111.26 ? 286 ILE R O   1 
ATOM   8883 C CB  . ILE E 5 824 ? 141.135 122.462 134.103 1.00 102.55 ? 286 ILE R CB  1 
ATOM   8884 C CG1 . ILE E 5 824 ? 140.821 123.550 133.075 1.00 105.82 ? 286 ILE R CG1 1 
ATOM   8885 C CG2 . ILE E 5 824 ? 142.637 122.335 134.282 1.00 99.56  ? 286 ILE R CG2 1 
ATOM   8886 C CD1 . ILE E 5 824 ? 141.371 124.911 133.434 1.00 106.92 ? 286 ILE R CD1 1 
ATOM   8887 N N   . LEU E 5 825 ? 141.150 119.567 135.428 1.00 96.54  ? 287 LEU R N   1 
ATOM   8888 C CA  . LEU E 5 825 ? 141.850 118.418 135.992 1.00 96.43  ? 287 LEU R CA  1 
ATOM   8889 C C   . LEU E 5 825 ? 141.147 117.118 135.619 1.00 96.99  ? 287 LEU R C   1 
ATOM   8890 O O   . LEU E 5 825 ? 140.276 117.100 134.750 1.00 95.30  ? 287 LEU R O   1 
ATOM   8891 C CB  . LEU E 5 825 ? 141.958 118.537 137.515 1.00 100.40 ? 287 LEU R CB  1 
ATOM   8892 C CG  . LEU E 5 825 ? 143.141 119.295 138.130 1.00 104.63 ? 287 LEU R CG  1 
ATOM   8893 C CD1 . LEU E 5 825 ? 144.340 118.367 138.284 1.00 102.90 ? 287 LEU R CD1 1 
ATOM   8894 C CD2 . LEU E 5 825 ? 143.521 120.534 137.333 1.00 102.49 ? 287 LEU R CD2 1 
HETATM 8895 C C1  . SA0 F 6 .   ? 140.421 138.550 164.314 1.00 98.47  ? 501 SA0 R C1  1 
HETATM 8896 O O1  . SA0 F 6 .   ? 140.067 139.752 164.967 1.00 101.30 ? 501 SA0 R O1  1 
HETATM 8897 C C2  . SA0 F 6 .   ? 141.926 138.574 164.108 1.00 97.20  ? 501 SA0 R C2  1 
HETATM 8898 O O2  . SA0 F 6 .   ? 142.288 139.676 163.281 1.00 104.78 ? 501 SA0 R O2  1 
HETATM 8899 C C3  . SA0 F 6 .   ? 142.356 137.266 163.482 1.00 87.37  ? 501 SA0 R C3  1 
HETATM 8900 O O3  . SA0 F 6 .   ? 143.777 137.231 163.362 1.00 91.50  ? 501 SA0 R O3  1 
HETATM 8901 C C4  . SA0 F 6 .   ? 141.868 136.098 164.316 1.00 90.90  ? 501 SA0 R C4  1 
HETATM 8902 O O4  . SA0 F 6 .   ? 142.174 134.872 163.663 1.00 97.10  ? 501 SA0 R O4  1 
HETATM 8903 C C5  . SA0 F 6 .   ? 140.364 136.189 164.519 1.00 95.80  ? 501 SA0 R C5  1 
HETATM 8904 O O5  . SA0 F 6 .   ? 140.041 137.456 165.124 1.00 99.72  ? 501 SA0 R O5  1 
HETATM 8905 C C6  . SA0 F 6 .   ? 139.832 135.115 165.438 1.00 101.69 ? 501 SA0 R C6  1 
HETATM 8906 O O6  . SA0 F 6 .   ? 140.427 135.201 166.730 1.00 105.47 ? 501 SA0 R O6  1 
HETATM 8907 O OAA . SA0 F 6 .   ? 140.478 141.280 166.908 1.00 101.47 ? 501 SA0 R OAA 1 
HETATM 8908 C CAF . SA0 F 6 .   ? 136.063 140.836 165.094 1.00 91.72  ? 501 SA0 R CAF 1 
HETATM 8909 C CAG . SA0 F 6 .   ? 136.448 139.719 164.391 1.00 89.01  ? 501 SA0 R CAG 1 
HETATM 8910 C CAH . SA0 F 6 .   ? 137.013 141.595 165.754 1.00 98.68  ? 501 SA0 R CAH 1 
HETATM 8911 C CAI . SA0 F 6 .   ? 137.777 139.349 164.345 1.00 87.67  ? 501 SA0 R CAI 1 
HETATM 8912 C CAJ . SA0 F 6 .   ? 139.393 142.072 166.446 1.00 102.06 ? 501 SA0 R CAJ 1 
HETATM 8913 C CAN . SA0 F 6 .   ? 138.362 141.246 165.723 1.00 99.58  ? 501 SA0 R CAN 1 
HETATM 8914 C CAO . SA0 F 6 .   ? 138.730 140.102 165.009 1.00 91.94  ? 501 SA0 R CAO 1 
# 
